BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9H227 (469 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3VKK-A nrPDB 977 0.0 3VIK-A nrPDB 424 e-119 5YJ7-A nrPDB 369 e-102 5CG0-A nrPDB 364 e-101 1WCG-A nrPDB 358 2e-99 3WBE-A nrPDB 342 3e-94 5W21-A nrPDB 341 4e-94 2RGL-A nrPDB 333 8e-92 4A3Y-A nrPDB 332 3e-91 2E40-A nrPDB 326 1e-89 4GXP-A nrPDB 326 1e-89 5WI9-A nrPDB 323 1e-88 3PTM-A nrPDB 323 1e-88 5VAQ-A nrPDB 321 5e-88 2CBU-A nrPDB 317 9e-87 4JIE-A nrPDB 316 1e-86 3ZJ8-A nrPDB 315 3e-86 3AIW-A nrPDB 311 3e-85 2DGA-A nrPDB 309 2e-84 3WQ4-A nrPDB 307 7e-84 1CBG-A nrPDB 306 1e-83 5IDI-A nrPDB 306 1e-83 1QOX-A nrPDB 296 1e-80 1V02-A nrPDB 295 2e-80 5JBO-A nrPDB 294 5e-80 4MDP-A nrPDB 293 9e-80 4HZ6-A nrPDB 293 9e-80 5OGZ-A nrPDB 290 1e-78 5BWF-A nrPDB 286 9e-78 3AHY-A nrPDB 283 8e-77 1BGG-A nrPDB 283 9e-77 1E55-A nrPDB 281 4e-76 4PTW-A nrPDB 269 2e-72 3AHX-A nrPDB 266 2e-71 5XGZ-A nrPDB 260 8e-70 5YHS-A nrPDB 257 6e-69 4ZEN-A nrPDB 254 4e-68 2Z1S-A nrPDB 248 3e-66 1W9D-M nrPDB 246 1e-65 1GNX-A nrPDB 242 2e-64 5GNX-A nrPDB 241 4e-64 5AYI-A nrPDB 241 6e-64 3W53-A nrPDB 228 3e-60 5NS7-A nrPDB 226 1e-59 5DT5-A nrPDB 219 2e-57 5WKA-A nrPDB 219 3e-57 3ZJK-A nrPDB 209 3e-54 1PBG-A nrPDB 208 5e-54 4F66-A nrPDB 180 1e-45 2XHY-A nrPDB 169 2e-42 4B3K-A nrPDB 165 5e-41 5NAV-A nrPDB 164 6e-41 1VFF-A nrPDB 160 1e-39 4GZE-A nrPDB 151 5e-37 4IPN-B nrPDB 150 9e-37 4R27-A nrPDB 124 7e-29 4HA4-A nrPDB 119 4e-27 1QVB-A nrPDB 111 8e-25 3WDP-P nrPDB 108 4e-24 1GOW-A nrPDB 98 7e-21 3NCO-A nrPDB 38 0.010 5H4R-A nrPDB 33 0.29 5GOQ-A nrPDB 31 0.90 3AZS-A nrPDB 30 2.2 3QR3-A nrPDB 30 2.2 3PDK-A nrPDB 29 4.4 1Y1U-A nrPDB 29 4.8 3AYR-A nrPDB 29 5.1 1XRE-A nrPDB 28 6.0 1CEO-A nrPDB 28 6.3 >3VKK-A nrPDB Length = 469 Score = 977 bits (2525), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/469 (99%), Positives = 469/469 (100%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITIN+ANVLSVMSYDLGMFP Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINQANVLSVMSYDLGMFP 180 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT Sbjct: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI Sbjct: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL Sbjct: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL Sbjct: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 >3VIK-A nrPDB Length = 487 Score = 424 bits (1091), Expect = e-119, Method: Compositional matrix adjust. Identities = 219/463 (47%), Positives = 298/463 (64%), Gaps = 9/463 (1%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F AATA+YQ+EG WD +GKGP +WDT TH+ + V TGD+A SY L++E Sbjct: 11 TFPDEFKLGAATASYQIEGAWDENGKGPNIWDTLTHEHPDYVVDGATGDIADDSYHLYKE 70 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+K +K+LG YRFS+SW+R+LP+G +NQ GIDYYN +I++LL NG+ P+VT+YH+ Sbjct: 71 DVKILKELGAQVYRFSISWARVLPEGHDNIVNQDGIDYYNNLINELLANGIEPMVTMYHW 130 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEA-NVLSVMSYDLGMFP 180 DLPQ L+D GGW + + + + YA+ F FGDRVK W+T N + + ++GM Sbjct: 131 DLPQALQDLGGWPNLVLAKYSENYARVLFKNFGDRVKLWLTFNSPLTFMDGYASEIGM-A 189 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 P I G G Y AAH +I AHAR +H YD FR +Q G V +SL W EPA NS D+ Sbjct: 190 PSINTPGIGDYLAAHTVIHAHARIYHLYDQEFRAEQGGKVGISLNINWCEPA-TNSAEDR 248 Query: 241 EAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKG 299 + + F+L L+A PIF +GDYP V+K +++ S +GY SRLP+FT EE + I+G Sbjct: 249 ASCENYQQFNLGLYAHPIFTEEGDYPAVLKDRVSRNSADEGYTDSRLPQFTAEEVEYIRG 308 Query: 300 TADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSW--KNVDWIYVVPWGVCKLL 357 T DF + +YT L K + E +D+ + D +W W+ VVPWG K L Sbjct: 309 THDFLGINFYTALLGK-SGVEGYEPSRYRDSGVILTQDAAWPISASSWLKVVPWGFRKEL 367 Query: 358 KYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 +IK+ YNNP ++ITENGF SD L+DT R Y+ + +E+ KAI D VN+ Y AW Sbjct: 368 NWIKNEYNNPPVFITENGF--SDYGGLNDTGRVHYYTEHLKEMLKAIHEDGVNVIGYTAW 425 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII 460 SL+DNFEW +GYS +FG++ VDFEDPARPR+P SAK A+I+ Sbjct: 426 SLMDNFEWLRGYSEKFGIYAVDFEDPARPRIPKESAKVLAEIM 468 >5YJ7-A nrPDB Length = 518 Score = 369 bits (947), Expect = e-102, Method: Compositional matrix adjust. Identities = 194/467 (41%), Positives = 277/467 (59%), Gaps = 24/467 (5%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 AFP GF W AATAAYQ+EG DG+GP +WDTF+ G ++ TGDVAC Y ++E Sbjct: 30 AFPEGFLWGAATAAYQIEGAAAEDGRGPSMWDTFSKIPG-KIDNGDTGDVACDHYHRYKE 88 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+K +K +GL YRFS+SWSR+LP+GT G IN KG+++Y + ++L+ NG+ P VTLYH+ Sbjct: 89 DVKLMKGMGLKSYRFSVSWSRVLPEGT-GAINPKGMEFYQNLTNELIANGIVPTVTLYHW 147 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLP+ L GGWL+E +F +YA F GDRVK W T+NE ++ Y G P Sbjct: 148 DLPEALSKNGGWLNEDTAVAFGQYADVMFQALGDRVKLWFTLNEPWTTAIAGYGQGGHAP 207 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G+ + Y A HN + HA + Y +++KQ G + L W EP ++ D++ Sbjct: 208 GLKNMAENPYMAGHNQLLGHAAAVKVYREKYQEKQGGKIGAVLSTEWKEPL-CHTQEDKD 266 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 AA+R++ ++L FA PI+ GDYPE +K ++ R+P FTE++K+ +KG+A Sbjct: 267 AAERSLIWYLAWFADPIY-KGDYPEEMKERVG----------DRMPAFTEQQKQDLKGSA 315 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKY 359 DFF + +Y T L++ K G D DP W + W+ VVPWG+ +LL++ Sbjct: 316 DFFGINHYATNLLQGPTEKIGAENYFSDLNGWIMMDPRWAVGDASWLSVVPWGMRRLLRW 375 Query: 360 IKDTYNNPVIYITENGF------PQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQV 413 IK Y++PV+Y+TENG + A L+D R +Y + E++KAI DKV + Sbjct: 376 IKHRYDDPVVYVTENGLSVPNESAMTPEAALNDKMRVDYLQGYVAEMWKAINYDKVKVAG 435 Query: 414 YCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII 460 Y WSLLDNFEW+ GY RFGL VD++ + R SAK Y +I Sbjct: 436 YYHWSLLDNFEWSDGYKVRFGLVQVDYK--TQKRTLKESAKVYKDMI 480 >5CG0-A nrPDB Length = 489 Score = 364 bits (935), Expect = e-101, Method: Compositional matrix adjust. Identities = 193/468 (41%), Positives = 275/468 (58%), Gaps = 11/468 (2%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + ATA+YQ+EG WD DGKG +WD H E + GD+A SY ++ D Sbjct: 5 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMVHNTPEVIRDLSNGDIAADSYHNYKRD 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +++LGL YRFSLSW+R+LP G +N GI +YN ID++LK +TP++TLYH+D Sbjct: 65 VEMMRELGLDAYRFSLSWARILPTGMANEVNPAGIAFYNNYIDEMLKYNITPLITLYHWD 124 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L++ GG+ + I + F+ YA+ F FGDRVK +IT NE + Y P Sbjct: 125 LPQKLQELGGFANPLISDWFEDYARVVFENFGDRVKMFITFNEPREICFEGYGSATKAPI 184 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + G Y A NL+ AHA++++ YD FR Q G +++ W PA P + D+ A Sbjct: 185 LNATAMGAYLCAKNLVTAHAKAYYLYDREFRPVQGGQCGITISVNWFGPATP-TPEDEMA 243 Query: 243 AKRAITFHLDLFAKPIF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 A+ ++A PIF +G +P+ + +IA S +QGYP SRLPEFTEEEK ++GT+ Sbjct: 244 AELRRQGEWGIYAHPIFSAEGGFPKELSDKIAEKSAQQGYPWSRLPEFTEEEKAFVRGTS 303 Query: 302 DFFAVQYYTTRLIKYQENKKGEL---GILQDAEIEFFPDPSW--KNVDWIYVVPWGVCKL 356 DFF V +YT L+ E +KG +L D + + D SW W+ + P + Sbjct: 304 DFFGVNHYTAFLVSATE-RKGPYPVPSLLDDVDTGSWADDSWLKSASAWLTLAPNSIHTA 362 Query: 357 LKYIKDTYNNPVIYITENGFP--QSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVY 414 L ++ + YN PV YITENG+ +S L D R +Y+R + + L + D +NL+ Y Sbjct: 363 LTHLNNLYNKPVFYITENGWSTDESRENSLIDDDRIQYYRASMESLLNCLD-DGINLKGY 421 Query: 415 CAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 AWSL+DNFEW +GY RFGL+ VDF DPAR R P +A Y II++ Sbjct: 422 MAWSLMDNFEWMEGYIERFGLYEVDFSDPARTRTPRKAAFVYKHIIKH 469 >1WCG-A nrPDB Length = 464 Score = 358 bits (919), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 182/461 (39%), Positives = 270/461 (58%), Gaps = 9/461 (1%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + +TA+YQ+EGGW+ DGKG +WD H E + GD+AC SY ++ED Sbjct: 5 FPKDFMFGTSTASYQIEGGWNEDGKGENIWDRLVHTSPEVIKDGTNGDIACDSYHKYKED 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + IK L L YRFS+SW+R+ P G + KGI YYN +I++L+KN + P+VT+YH+D Sbjct: 65 VAIIKDLNLKFYRFSISWARIAPSGVMNSLEPKGIAYYNNLINELIKNDIIPLVTMYHWD 124 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L+D GGW++ + + F +YA+ F+ FGDRVK WIT NE + Y + + P Sbjct: 125 LPQYLQDLGGWVNPIMSDYFKEYARVLFTYFGDRVKWWITFNEP-IAVCKGYSIKAYAPN 183 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + TG Y A H + AH +++ Y+ +F+ Q G +S+S+ V+ P + S D E Sbjct: 184 LNLKTTGHYLAGHTQLIAHGKAYRLYEEMFKPTQNGKISISISGVFFMPKNAESDDDIET 243 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A+RA F F P++ GDYP ++K + S+++G P S+LP+FT++E K++KGTAD Sbjct: 244 AERANQFERGWFGHPVY-KGDYPPIMKKWVDQKSKEEGLPWSKLPKFTKDEIKLLKGTAD 302 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSW---KNVDWIYVVPWGVCKLLKY 359 F+A+ +Y++RL+ + + DA D +W +I VP G+ KLL + Sbjct: 303 FYALNHYSSRLVTFGSDPNPNFN--PDASYVTSVDEAWLKPNETPYIIPVPEGLRKLLIW 360 Query: 360 IKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSL 419 +K+ Y NP + ITENG+ D LDD ++ Y + +A+ DK N+ Y WSL Sbjct: 361 LKNEYGNPQLLITENGY--GDDGQLDDFEKISYLKNYLNATLQAMYEDKCNVIGYTVWSL 418 Query: 420 LDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII 460 LDNFEW GYS FGL +DF DP R R S + ++ Sbjct: 419 LDNFEWFYGYSIHFGLVKIDFNDPQRTRTKRESYTYFKNVV 459 >3WBE-A nrPDB Length = 489 Score = 342 bits (876), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 192/487 (39%), Positives = 276/487 (56%), Gaps = 42/487 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 +FP GF + A+AAYQ EG DG+G +WDTF H G ++ DVA Y +EE Sbjct: 17 SFPEGFVFGTASAAYQYEGAVKEDGRGQTIWDTFAHTFG-KITDFSNADVAVDQYHRFEE 75 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ + +G+ YRFS++WSR+ P+G G +NQ GID+YNK+ID LL G+ P VTLYH+ Sbjct: 76 DIQLMADMGMDAYRFSIAWSRIYPNGV-GQVNQAGIDHYNKLIDALLAKGIQPYVTLYHW 134 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLPQ LED+ GWL I++ F YA+ CF FGDRVK WIT+N+ + +++ YD G+ Sbjct: 135 DLPQALEDKYKGWLDRQIVDDFAAYAETCFREFGDRVKHWITLNQPHTVAIQGYDAGLQA 194 Query: 181 PG----IPHF-------GTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 PG + H GT Y AH+ I AHA + Y + ++ Q G + ++ +W Sbjct: 195 PGRCSVLLHLYCKAGNSGTEPYVVAHHFILAHAAAASIYRTKYKATQNGQLGIAFDVMWF 254 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 EP N+ D EAAKRA F L FA P F GDYP +++++ RLP F Sbjct: 255 EPMS-NTTIDIEAAKRAQEFQLGWFADPFFF-GDYPATMRARVG----------ERLPRF 302 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLIKYQE-NKKGEL--GILQDAEIEFFPDPSWK----- 341 T +E ++KG DF + +YTT ++ N G L L D P + K Sbjct: 303 TADEAAVVKGALDFVGINHYTTYYTRHNNTNIIGTLLNNTLADTGTVSLPFKNGKPIGDR 362 Query: 342 -NVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD------PAPLDDTQRWEYFR 394 N W+Y+VP G+ L+ Y+K+ YN+P +YITENG S+ L D++R +Y Sbjct: 363 ANSIWLYIVPRGMRSLMNYVKERYNSPPVYITENGMDDSNNPFISIKDALKDSKRIKYHN 422 Query: 395 QTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 L +I+ D +++ Y AWSLLDN+EW GYSSRFGL+ VD++D + R P S + Sbjct: 423 DYLTNLAASIKEDGCDVRGYFAWSLLDNWEWAAGYSSRFGLYFVDYKDNLK-RYPKNSVQ 481 Query: 455 EYAKIIR 461 + +++ Sbjct: 482 WFKALLK 488 >5W21-A nrPDB Length = 981 Score = 341 bits (874), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 200/482 (41%), Positives = 278/482 (57%), Gaps = 53/482 (10%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQ---------------GGERVFKN 46 FP GF WA +AAYQ EGGW GKG +WDTFTH G + Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119 Query: 47 QTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDD 106 TGDVA SY D + +++LG+THYRFS+SW+R+LP+G+ G N++G+ YY ++++ Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179 Query: 107 LLKNGVTPIVTLYHFDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165 L + GV P+VTLYH+DLPQ L+D GGW + A+ + F YA+ CF FG +VK WITI+ Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239 Query: 166 ANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLF 225 V++ Y G PGI GY AHNL+ AHA+ WH Y++ FR Q G VS++L Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALS 299 Query: 226 AVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSR 285 + W+ P S +E K ++ F L FAKP+FIDGDYPE +K+ ++S+ Sbjct: 300 SHWINPRRMTDHSIKECQK-SLDFVLGWFAKPVFIDGDYPESMKNNLSSI---------- 348 Query: 286 LPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEF--FPDPSWKNV 343 LP+FTE EKK IKGTADFFA+ + T + +Q L D ++F P+ + Sbjct: 349 LPDFTESEKKFIKGTADFFALCFGPT--LSFQ---------LLDPHMKFRQLESPNLR-- 395 Query: 344 DWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKA 403 +LL +I +N+P I+I ENG+ S DD + Y ++ E KA Sbjct: 396 -----------QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKA 444 Query: 404 IQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 I+LD V++ Y AWSL+D FEW++GYS R GLF+VDF + +P +SA Y K+I N Sbjct: 445 IKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKN 504 Query: 464 GL 465 G Sbjct: 505 GF 506 Score = 228 bits (582), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 145/419 (34%), Positives = 215/419 (51%), Gaps = 43/419 (10%) Query: 53 CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112 C + + + ++++ +TH+RFSL W+ +LP G +N + YY + +L++ + Sbjct: 572 CVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNI 631 Query: 113 TPIVTLY-----HFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEAN 167 TP+V L+ + LP+ L QG W + +F +YA+ CF G VK WIT+NE Sbjct: 632 TPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNE-- 689 Query: 168 VLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAV 227 P+ Y A HNL+KAHA +WH Y+ FR Q G +S++L A Sbjct: 690 ----------------PYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQAD 733 Query: 228 WLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLP 287 W+EPA P S D+E A+R + F + A+PIF GDYP V++ ++Q+ + LP Sbjct: 734 WIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDW---LNQRNNF---LLP 787 Query: 288 EFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNV-DWI 346 FTE+EKK+I+GT DF A+ +YTT L+ K+ + E++ D +W N + Sbjct: 788 YFTEDEKKLIQGTFDFLALSHYTTILV--DSEKEDPIKYNDYLEVQEMTDITWLNSPSQV 845 Query: 347 YVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQL 406 VVPWG+ K+L ++K Y + +YI NG A DD R Y + E KA L Sbjct: 846 AVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAE-DDQLRVYYMQNYINEALKAHIL 904 Query: 407 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 D +NL Y A+S N + RFGL+ A P S K Y KII +NG Sbjct: 905 DGINLCGYFAYSF------NDRTAPRFGLYRY----AADQFEPKASMKHYRKIIDSNGF 953 >2RGL-A nrPDB Length = 481 Score = 333 bits (855), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 186/463 (40%), Positives = 264/463 (57%), Gaps = 34/463 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 AFP F + T+AYQVEG + G+GP +WD F H G V NQ GDVA Y ++E Sbjct: 19 AFPKRFVFGTVTSAYQVEGMAASGGRGPSIWDAFAHTPGN-VAGNQNGDVATDQYHRYKE 77 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+ +K L YRFS+SWSR+ PDG G +NQ+G+ YYN +I+ LL+ G+TP V LYH+ Sbjct: 78 DVNLMKSLNFDAYRFSISWSRIFPDGE-GRVNQEGVAYYNNLINYLLQKGITPYVNLYHY 136 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP LE + GGWL+ + + F +YA FCF TFG+RVK W T NE +++++ YD G P Sbjct: 137 DLPLALEKKYGGWLNAKMADLFTEYADFCFKTFGNRVKHWFTFNEPRIVALLGYDQGTNP 196 Query: 181 PG-IPHFGTGG------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPAD 233 P GG Y AHN + +HA + Y + ++ Q+G V + L W E A Sbjct: 197 PKRCTKCAAGGNSATEPYIVAHNFLLSHAAAVARYRTKYQAAQQGKVGIVLDFNWYE-AL 255 Query: 234 PNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEE 293 NS DQ AA+RA FH+ + P+ I+G YP++++ + RLP+FT E+ Sbjct: 256 SNSTEDQAAAQRARDFHIGWYLDPL-INGHYPQIMQDLV----------KDRLPKFTPEQ 304 Query: 294 KKMIKGTADFFAVQYYTTRLIKYQE-NKKGELGILQDAEIEFF------PDPSWKNVDWI 346 +++KG+AD+ + YT +K Q+ ++ D ++ + P N +W+ Sbjct: 305 ARLVKGSADYIGINQYTASYMKGQQLMQQTPTSYSADWQVTYVFAKNGKPIGPQANSNWL 364 Query: 347 YVVPWGVCKLLKYIKDTYNNPVIYITENGFPQ----SDPAPLDDTQRWEYFRQTFQELFK 402 Y+VPWG+ + YIK Y NP + ITENG Q S L DT R ++R +L K Sbjct: 365 YIVPWGMYGCVNYIKQKYGNPTVVITENGMDQPANLSRDQYLRDTTRVHFYRSYLTQLKK 424 Query: 403 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPAR 445 AI + N+ Y AWSLLDNFEW GY+S+FG+ +VDF R Sbjct: 425 AID-EGANVAGYFAWSLLDNFEWLSGYTSKFGIVYVDFNTLER 466 >4A3Y-A nrPDB Length = 540 Score = 332 bits (850), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 193/485 (39%), Positives = 273/485 (56%), Gaps = 57/485 (11%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FPA F ++AYQ+EGG G+GP +WDTFTH+ + + GDVA SY L++ED Sbjct: 22 FPADFIMGTGSSAYQIEGGARDGGRGPSIWDTFTHRRPDMIRGGTNGDVAVDSYHLYKED 81 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + +K LGL YRFS+SWSR+LP G +G +N++GI+YYN +ID LL NG+ P VTL+H+ Sbjct: 82 VNILKNLGLDAYRFSISWSRVLPGGRLSGGVNKEGINYYNNLIDGLLANGIKPFVTLFHW 141 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 D+PQ LED+ GG+LS I++ F +YA+ CF FGDRVK W+T+NE SV Y G++ Sbjct: 142 DVPQALEDEYGGFLSPRIVDDFCEYAELCFWEFGDRVKHWMTLNEPWTFSVHGYATGLYA 201 Query: 181 PG-------------IPHF---------------GTGGYQAAHNLIKAHARSWHSYDSLF 212 PG + H GT Y H+L+ AHA + Y + F Sbjct: 202 PGRGRTSPEHVNHPTVQHRCSTVAPQCICSTGNPGTEPYWVTHHLLLAHAAAVELYKNKF 261 Query: 213 RKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQI 272 ++ Q+G + +S W+EP D NS SD EAA RA+ F L F +PI GDYP+ +K + Sbjct: 262 QRGQEGQIGISHATQWMEPWDENSASDVEAAARALDFMLGWFMEPI-TSGDYPKSMKKFV 320 Query: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLI-KYQENKKG--------E 323 SRLP+F+ E+ KM+KG+ DF + YYT + N G + Sbjct: 321 G----------SRLPKFSPEQSKMLKGSYDFVGLNYYTASYVTNASTNSSGSNNFSYNTD 370 Query: 324 LGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP 383 + + + + P DW+ + P G+ K+L Y K TYN P+IY+TENG Sbjct: 371 IHVTYETDRNGVPIGPQSGSDWLLIYPEGIRKILVYTKKTYNVPLIYVTENGVDDVKNTN 430 Query: 384 L------DDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFH 437 L D+ R +Y + + +A+ D VN++ Y AWSLLDNFEW +GY RFG+ H Sbjct: 431 LTLSEARKDSMRLKYLQDHIFNVRQAMN-DGVNVKGYFAWSLLDNFEWGEGYGVRFGIIH 489 Query: 438 VDFED 442 +D+ D Sbjct: 490 IDYND 494 >2E40-A nrPDB Length = 465 Score = 326 bits (836), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 193/465 (41%), Positives = 269/465 (57%), Gaps = 33/465 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 P F W ATAAYQ+EG D DG+ P +WDTF G ++ +GDVA SY W ED Sbjct: 9 LPKSFVWGYATAAYQIEGSPDKDGREPSIWDTFCKAPG-KIADGSSGDVATDSYNRWRED 67 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDG-TTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 ++ +K G+ YRFSLSWSR++P G + +N GI +Y +I++L+K G+TP VTLYH+ Sbjct: 68 VQLLKSYGVKAYRFSLSWSRIIPKGGRSDPVNGAGIKHYRTLIEELVKEGITPFVTLYHW 127 Query: 122 DLPQTLEDQ-GGWLS-EAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 DLPQ L+D+ GGWL+ E I+ F YA+ CF +FGD V+ WIT NE V+SVM Y G+F Sbjct: 128 DLPQALDDRYGGWLNKEEAIQDFTNYAKLCFESFGDLVQNWITFNEPWVISVMGYGNGIF 187 Query: 180 PPGIPHFG-TGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVS 238 PG H T + +H++I AHA + Y F++KQ G + ++L + WL P D S Sbjct: 188 APG--HVSNTEPWIVSHHIILAHAHAVKLYRDEFKEKQGGQIGITLDSHWLIPYDDTDAS 245 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298 +EA RA+ F L FA PI+ G+YP +K + RLPEFT EE +++K Sbjct: 246 -KEATLRAMEFKLGRFANPIY-KGEYPPRIKKILGD----------RLPEFTPEEIELVK 293 Query: 299 GTADFFAVQYYTTRLIKYQENKKGEL-GILQDAEIEFFPDP--SWKNVDWIYVVPWGVCK 355 G++DFF + YTT L+ Q+ EL G ++ + ++ W+ G Sbjct: 294 GSSDFFGLNTYTTHLV--QDGGSDELAGFVKTGHTRADGTQLGTQSDMGWLQTYGPGFRW 351 Query: 356 LLKYIKDTYNNPVIYITENGFPQSDPAPL------DDTQRWEYFRQTFQELFKAIQLDKV 409 LL Y+ Y+ PV Y+TENGFP L DDT R Y+R + L +A+ D Sbjct: 352 LLNYLWKAYDKPV-YVTENGFPVKGENDLPVEQAVDDTDRQAYYRDYTEALLQAVTEDGA 410 Query: 410 NLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 +++ Y WSLLDNFEW +GY RFG+ HVD+E + R P SA+ Sbjct: 411 DVRGYFGWSLLDNFEWAEGYKVRFGVTHVDYE--TQKRTPKKSAE 453 >4GXP-A nrPDB Length = 467 Score = 326 bits (836), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 184/474 (38%), Positives = 271/474 (57%), Gaps = 30/474 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W ATA+YQ+EG ADG G +W TF+H G V TGDVAC Y W+ED Sbjct: 13 FPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGN-VKNGDTGDVACDHYNRWKED 71 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ I++LG+ YRFS+SW R+LP+GT G +NQKG+D+YN+IID LL+ G+TP VT++H+D Sbjct: 72 IEIIEKLGVKAYRFSISWPRILPEGT-GRVNQKGLDFYNRIIDTLLEKGITPFVTIFHWD 130 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LP L+ +GG L+ I + F +Y++ F FGDRVK WIT NE ++ Y G F PG Sbjct: 131 LPFALQLKGGLLNREIADWFAEYSRVLFENFGDRVKNWITFNEPLCSAIPGYGSGTFAPG 190 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + + HN++ AH R+ + + + G+V F + ADP +D+EA Sbjct: 191 -RQSTSEPWTVGHNILVAHGRAVKVFRETVKDGKIGIVLNGDFTYPWDAADP---ADKEA 246 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A+R + F FA PI++ GDYP ASM ++ G RLP FT EE+ ++ G+ D Sbjct: 247 AERRLEFFTAWFADPIYL-GDYP-------ASMRKQLG---DRLPTFTPEERALVHGSND 295 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPW------GVCKL 356 F+ + +YT+ I+++ + + + ++ F + + +PW G Sbjct: 296 FYGMNHYTSNYIRHRSSPASADDTVGNVDV-LFTNKQGNCIGPETAMPWLRPCAAGFRDF 354 Query: 357 LKYIKDTYNNPVIYITENGFPQSDPAPLD----DTQRWEYFRQTFQELFKAIQLDKVNLQ 412 L +I Y P IY+TENG D D D R +Y + + A++LD VN++ Sbjct: 355 LVWISKRYGYPPIYVTENGAAFDDVVSEDGRVHDQNRIDYLKAYIGAMVTAVELDGVNVK 414 Query: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 Y WSLLDNFEW +GYS RFG+ +VD+ + R+ S Y+ +++NNGLE Sbjct: 415 GYFVWSLLDNFEWAEGYSKRFGIVYVDYS--TQKRIVKDSGYWYSNVVKNNGLE 466 >5WI9-A nrPDB Length = 470 Score = 323 bits (827), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 177/466 (37%), Positives = 254/466 (54%), Gaps = 37/466 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F W T A QVEG W DGKGP +WD F H + V + + + SY E+ Sbjct: 29 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYIFLEK 85 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL + +G++ Y+FS+SW RL PDG N KG+ YY+ ++D L+ + PIVTLYH+ Sbjct: 86 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 145 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP L+++ GGW ++ II+ F+ YA +CF FGDRVK WITI+ +++ Y GM Sbjct: 146 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 205 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG Y HNLIKAH++ WH+Y++ FR QKG +S++L + W+EP + D Sbjct: 206 PGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDI 265 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 ++++ L FA PI DGDYPE ++ ++ S+ LP F+E EK ++GT Sbjct: 266 FKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGT 315 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADFFA + N ++G Q+ + + + L +I Sbjct: 316 ADFFAFSFGPNNFKPL--NTMAKMG--QNVSLN-------------------LREALNWI 352 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 K YNNP I I ENG+ +DT + ++ +AI+LD++ + Y AWSLL Sbjct: 353 KLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLL 412 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 D FEW Y+ R GLF+VDF + R P +SA Y +IIR NG E Sbjct: 413 DGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFE 458 >3PTM-A nrPDB Length = 505 Score = 323 bits (827), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 192/489 (39%), Positives = 272/489 (55%), Gaps = 48/489 (9%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 +FP GF + A+++YQ EGG G+GP +WDTFTHQ E++ GDVA SY L++E Sbjct: 33 SFPKGFIFGTASSSYQYEGGAAEGGRGPSIWDTFTHQHPEKIADRSNGDVASDSYHLYKE 92 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D++ +K +G+ YRFS+SW+R+LP+G+ G +N++GI YYN +I++LL GV P +TL+H Sbjct: 93 DVRLMKDMGMDAYRFSISWTRILPNGSLRGGVNKEGIKYYNNLINELLSKGVQPFITLFH 152 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 +D PQ LED+ G+LS II F YA+ CF FGDRVK WIT NE Y G+F Sbjct: 153 WDSPQALEDKYNGFLSPNIINDFKDYAEICFKEFGDRVKNWITFNEPWTFCSNGYATGLF 212 Query: 180 PPG-----------IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 PG + G Y A H+ + AHA + Y + ++ QKG + ++L + W Sbjct: 213 APGRCSPWEKGNCSVGDSGREPYTACHHQLLAHAETVRLYKAKYQALQKGKIGITLVSHW 272 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 P S S+ +AAKRAI F F P+ I GDYP ++ G +RLP+ Sbjct: 273 FVPFS-RSKSNNDAAKRAIDFMFGWFMDPL-IRGDYPLSMR----------GLVGNRLPQ 320 Query: 289 FTEEEKKMIKGTADFFAVQYYTTRLI-----------KYQENKKGELGILQDAEIEFFPD 337 FT+E+ K++KG DF + YYT Y + + L +++ I P Sbjct: 321 FTKEQSKLVKGAFDFIGLNYYTANYADNLPPSNGLNNSYTTDSRANLTGVRNG-IPIGPQ 379 Query: 338 PSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD------PAPLDDTQRWE 391 + W+YV P G LL Y+K+ Y NP +YITENG + + L D R E Sbjct: 380 AA---SPWLYVYPQGFRDLLLYVKENYGNPTVYITENGVDEFNNKTLPLQEALKDDARIE 436 Query: 392 YFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYT 451 Y+ + L AI+ D N++ Y AWSLLDNFEW+ GY+ RFG+ VD+ D R R P Sbjct: 437 YYHKHLLSLLSAIR-DGANVKGYFAWSLLDNFEWSNGYTVRFGINFVDYND-GRKRYPKN 494 Query: 452 SAKEYAKII 460 SA + K + Sbjct: 495 SAHWFKKFL 503 >5VAQ-A nrPDB Length = 954 Score = 321 bits (822), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 177/465 (38%), Positives = 253/465 (54%), Gaps = 37/465 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F W T A QVEG W DGKGP +WD F H + V + + + SY E+ Sbjct: 51 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYIFLEK 107 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL + +G++ Y+FS+SW RL PDG N KG+ YY+ ++D L+ + PIVTLYH+ Sbjct: 108 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 167 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP L+++ GGW ++ II+ F+ YA +CF FGDRVK WITI+ +++ Y GM Sbjct: 168 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 227 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG Y HNLIKAH++ WH+Y++ FR QKG +S++L + W+EP + D Sbjct: 228 PGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPQRSENTMDI 287 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 ++++ L FA PI DGDYPE ++ ++ S+ LP F+E EK ++GT Sbjct: 288 FKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGT 337 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADFFA + N ++G +NV + + L +I Sbjct: 338 ADFFAFSFGPNNFKPL--NTMAKMG---------------QNVS------LNLREALNWI 374 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 K YNNP I I ENG+ +DT + ++ +AI+LD++ + Y AWSLL Sbjct: 375 KLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLL 434 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 D FEW Y+ R GLF+VDF + R P +SA Y +IIR NG Sbjct: 435 DGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGF 479 Score = 266 bits (680), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 165/474 (34%), Positives = 250/474 (52%), Gaps = 38/474 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDA---DGKGPCVWDTFTHQGGERV--FKNQTGDVACGSYT 57 FP F W + + E + VW+ ++ RV + +T C + Sbjct: 492 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFV 551 Query: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117 ++ L+ + ++ +THYRF+L W+ +LP G +N++ + YY ++ + LK G++ +VT Sbjct: 552 NIKKQLEMLARMKVTHYRFALDWASVLPTGQLSAVNRQALRYYRCVVSEGLKLGISAMVT 611 Query: 118 LY-----HFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVM 172 LY H LP+ L GWL+ + E+F YA CF GD VK WITINE N LS + Sbjct: 612 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 671 Query: 173 SYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPA 232 Y+ G Y AAHNL+ AHA +W YD FR Q+G VSLSL A W EPA Sbjct: 672 -YNRS---------GNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPA 721 Query: 233 DPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEE 292 +P + S AA+R + F + FA+P+F GDYP ++ IAS ++G SS LP TE Sbjct: 722 NPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIAS-KHRRGLSSSALPRLTEA 780 Query: 293 EKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPS-WKNVDWIYVVPW 351 E++++KGT DF A+ ++TTR + +++ D +I+F D + + + V+PW Sbjct: 781 ERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYD--SDRDIQFLQDITRLSSPTRLAVIPW 838 Query: 352 GVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNL 411 GV KLL++++ Y + IYIT +G D A DD R Y + QE+ KA +DKV + Sbjct: 839 GVRKLLRWVRRNYGDMDIYITASGI--DDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRI 896 Query: 412 QVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 + Y A+ L + + RFG F DF+ +S + Y K+I + G Sbjct: 897 KGYYAFKLAE-----EKSKPRFGFFTSDFKAK-------SSIQFYNKVISSRGF 938 >2CBU-A nrPDB Length = 468 Score = 317 bits (811), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 184/473 (38%), Positives = 274/473 (57%), Gaps = 42/473 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W ATA+YQ+EG ADG G +W TF+H G V TGDVAC Y W+ED Sbjct: 28 FPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGN-VKNGDTGDVACDHYNRWKED 86 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ I++LG+ YRFS+SW R+LP+GT G +NQKG+D+YN+IID LL+ G+TP VT+YH+D Sbjct: 87 IEIIEKLGVKAYRFSISWPRILPEGT-GRVNQKGLDFYNRIIDTLLEKGITPFVTIYHWD 145 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LP L+ +GGW + I + F +Y++ F FGDRVK WIT+NE V++++ + G+ PG Sbjct: 146 LPFALQLKGGWANREIADWFAEYSRVLFENFGDRVKNWITLNEPWVVAIVGHLYGVHAPG 205 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQK-GMVSLSLFAVWLEPADPNSVSDQE 241 + ++A HNL++AHAR+ +FR+ K G + + + EPA S++E Sbjct: 206 MRDIYV-AFRAVHNLLRAHARA----VKVFRETVKDGKIGIVFNNGYFEPA-----SEKE 255 Query: 242 AAKRAITFHLDLFAKPIFID----GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMI 297 RA+ F P+F++ GDYPE+V + LPE +++ I Sbjct: 256 EDIRAVRFMHQFNNYPLFLNPIYRGDYPELVLE----------FAREYLPENYKDDMSEI 305 Query: 298 KGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLL 357 + DF + YY+ L+K+ + ++ ++ D + W +VP G+ +L Sbjct: 306 QEKIDFVGLNYYSGHLVKFDPDAPAKVSFVER-------DLPKTAMGW-EIVPEGIYWIL 357 Query: 358 KYIKDTYNNPVIYITENGFPQSDPAPLD----DTQRWEYFRQTFQELFKAIQLDKVNLQV 413 K +K+ YN P +YITENG D D D R +Y + + +KAIQ + V L+ Sbjct: 358 KKVKEEYNPPEVYITENGAAFDDVVSEDGRVHDQNRIDYLKAHIGQAWKAIQ-EGVPLKG 416 Query: 414 YCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 Y WSLLDNFEW +GYS RFG+ +VD+ + R+ S Y+ +++NNGLE Sbjct: 417 YFVWSLLDNFEWAEGYSKRFGIVYVDYS--TQKRIVKDSGYWYSNVVKNNGLE 467 >4JIE-A nrPDB Length = 503 Score = 316 bits (809), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 189/471 (40%), Positives = 263/471 (55%), Gaps = 50/471 (10%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 AFP GF + A +AYQVEG G+GP +WD F + G + N T DV Y ++E Sbjct: 37 AFPEGFVFGTAASAYQVEGMAKQGGRGPSIWDAFIEKPGT-IPNNATADVTVDEYHRYKE 95 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+ +K +G YRFS+SWSR+ P+GT G +NQ+G+DYYN++ID ++K G+ P LYH+ Sbjct: 96 DVNIMKNMGFDAYRFSISWSRIFPNGT-GMVNQEGVDYYNRLIDYMVKKGIKPYANLYHY 154 Query: 122 DLPQTLEDQG-GWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP L +Q GWLS I+E+F YA FCF TFGDRVK W T NE ++ + YD G Sbjct: 155 DLPLALHEQYLGWLSPNIVEAFADYADFCFQTFGDRVKDWFTFNEPRCVAALGYDNGFHA 214 Query: 181 PGIPHFGTGG-------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPAD 233 PG G Y AAH+LI +HA + Y ++ QKG + + L VW EP Sbjct: 215 PGRCSGCDAGGNSTTEPYLAAHHLILSHAAAVKRYREKYQLYQKGRIGILLDFVWYEPFS 274 Query: 234 PNSVSDQEAAKRAITFHLDLFAKPIFIDGDYP----EVVKSQIASMSQKQGYPSSRLPEF 289 +S +D+ AA+RA FHL F PI I G YP E+VK R+P F Sbjct: 275 -DSNADRAAAQRARDFHLGWFLDPI-IHGRYPYSMLEIVK--------------DRMPTF 318 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLIK-----------YQENKKGELGILQDAEIEFFPDP 338 ++EE +M+K + D+ + +YT+ +K YQ++ ++ P Sbjct: 319 SDEESRMVKDSIDYVGINHYTSFYMKDPGPWNLTPTSYQDDWHVGFAYERNG----VPIG 374 Query: 339 SWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQ----SDPAPLDDTQRWEYFR 394 + N W+Y+VPWG+ K + Y+K+TY NP + ++ENG Q S + DT R Y+R Sbjct: 375 AQANSYWLYIVPWGINKAVTYVKETYGNPTMILSENGMDQPGNVSITQGVHDTVRIRYYR 434 Query: 395 QTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPAR 445 EL KAI D + Y AWSLLDNFEW GY+SRFG+ +VD++ R Sbjct: 435 NYITELKKAID-DGAKVIGYFAWSLLDNFEWRLGYTSRFGIVYVDYKTLKR 484 >3ZJ8-A nrPDB Length = 532 Score = 315 bits (807), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 177/479 (36%), Positives = 272/479 (56%), Gaps = 36/479 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + A +AYQ EG ++ +GP +WDTFT + ++ G+ A Y +++ED Sbjct: 43 FPQDFIFGAGGSAYQCEGAYNEGNRGPSIWDTFTQRSPAKISDGSNGNQAINCYHMYKED 102 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 +K +KQ GL YRFS+SWSR+LP G +N+ G+ +Y+ ID+LL NG+ P VTL+H+ Sbjct: 103 IKIMKQTGLESYRFSISWSRVLPGGRLAAGVNKDGVKFYHDFIDELLANGIKPSVTLFHW 162 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLPQ LED+ GG+LS I++ F +YA+FCF FGD++K W T NE + +V Y LG F Sbjct: 163 DLPQALEDEYGGFLSHRIVDDFCEYAEFCFWEFGDKIKYWTTFNEPHTFAVNGYALGEFA 222 Query: 181 PGIPHFGTGG------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADP 234 PG G G Y HN++ AH + Y + F+K Q+G + + L ++W+EP Sbjct: 223 PGRGGKGDEGDPAIEPYVVTHNILLAHKAAVEEYRNKFQKCQEGEIGIVLNSMWMEPLS- 281 Query: 235 NSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294 + +D +A KRA+ F L F +P+ GDYP+ ++ + RLP+F+ ++ Sbjct: 282 DVQADIDAQKRALDFMLGWFLEPL-TTGDYPKSMRELV----------KGRLPKFSADDS 330 Query: 295 KMIKGTADFFAVQYYT-TRLIKYQENKKGELGILQDAEIEFFPDPSWKNV------DWIY 347 + +KG DF + YYT T + ++ +L D ++ + + K + W + Sbjct: 331 EKLKGCYDFIGMNYYTATYVTNAVKSNSEKLSYETDDQVTKTFERNQKPIGHALYGGWQH 390 Query: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPL------DDTQRWEYFRQTFQELF 401 VVPWG+ KLL Y K+TY+ PV+Y+TE+G + + + D +R +Y ++ + Sbjct: 391 VVPWGLYKLLVYTKETYHVPVLYVTESGMVEENKTKILLSEARRDAERTDYHQKHLASVR 450 Query: 402 KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII 460 AI D VN++ Y WS DNFEWN GY R+G+ HVD++ + R P SA Y I Sbjct: 451 DAID-DGVNVKGYFVWSFFDNFEWNLGYICRYGIIHVDYK--SFERYPKESAIWYKNFI 506 >3AIW-A nrPDB Length = 564 Score = 311 bits (798), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 176/482 (36%), Positives = 269/482 (55%), Gaps = 41/482 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 F F + A+T+AYQ+EG W+ DGKGP WD F H ER+ GDVA SY ++EED Sbjct: 74 FSKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHTYPERISDGTNGDVAANSYHMYEED 133 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 +K +K +G+ YRFS+SWSR+LP+G TG NQKGIDYYN +I+ L+++G+ P VT++H+D Sbjct: 134 VKALKDMGMKVYRFSISWSRILPNG-TGKPNQKGIDYYNNLINSLIRHGIVPYVTIWHWD 192 Query: 123 LPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 PQ LED+ GG+L + I+ + +A+ CF +FGDRVK W T NE + SY G+ P Sbjct: 193 TPQALEDKYGGFLDKQIVNDYKYFAELCFQSFGDRVKNWFTFNEPHTYCCFSYGEGIHAP 252 Query: 182 GIPHFGTGG-----------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLE 230 G G Y A H+++ AHA + + + + K + ++ + E Sbjct: 253 GRCSPGLDCAVPEGDSLREPYTAGHHILLAHAEAVELFKAHYNKHGDSKIGMAFDVMGYE 312 Query: 231 PADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFT 290 P +S D +A +R+I +++ F +P+ + GDYP ++S I RLP FT Sbjct: 313 PYQ-DSFLDDQARERSIDYNMGWFLEPV-VRGDYPFSMRSLIG----------DRLPMFT 360 Query: 291 EEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD------ 344 +EE++ + + D + YYT+R K+ + L + + + + + Sbjct: 361 KEEQEKLASSCDIMGLNYYTSRFSKHVDISSDYTPTLNTDDAYASSETTGSDGNEIGPIT 420 Query: 345 ---WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD-----PAPLDDTQRWEYFRQT 396 WIY+ P G+ LL +K+ Y NP I+ITENG + P PLDD +R +Y ++ Sbjct: 421 GTYWIYMYPKGLTDLLLIMKEKYGNPPIFITENGIADVEGDPEMPDPLDDWKRLDYLQRH 480 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 + AI +++ + W L+DNFEW GYSSRFGL ++D ED + ++ SAK + Sbjct: 481 ISAVKDAID-QGADVRGHFTWGLIDNFEWGSGYSSRFGLVYIDKEDGNKRKLK-KSAKWF 538 Query: 457 AK 458 AK Sbjct: 539 AK 540 >2DGA-A nrPDB Length = 565 Score = 309 bits (792), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 175/482 (36%), Positives = 269/482 (55%), Gaps = 41/482 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 F F + A+T+AYQ+EG W+ DGKGP WD F H ER+ GDVA SY L+EED Sbjct: 74 FDKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHTYPERISDMTNGDVAANSYHLYEED 133 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 +K +K +G+ YRFS+SWSR+LPDG TG +NQ GIDYYNK+I+ L+ N + P VT++H+D Sbjct: 134 VKALKDMGMKVYRFSISWSRILPDG-TGKVNQAGIDYYNKLINSLIDNDIVPYVTIWHWD 192 Query: 123 LPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 PQ LED+ GG+L+ I++ + ++A+ CF FGDRVK W T NE + SY G+ P Sbjct: 193 TPQALEDKYGGFLNRQIVDDYKQFAEVCFKNFGDRVKNWFTFNEPHTYCCFSYGEGIHAP 252 Query: 182 GIPHFGTGG-----------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLE 230 G G Y A H+++ AHA + + + + + ++ + E Sbjct: 253 GRCSPGMDCAVPEGDSLREPYTAGHHILLAHAEAVQLFKARYNMHGDSKIGMAFDVMGYE 312 Query: 231 PADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFT 290 P +S D +A +R+I +++ F +P+ + GDYP ++S I RLP FT Sbjct: 313 PYQ-DSFLDDQARERSIDYNMGWFLEPV-VRGDYPFSMRSLIG----------DRLPMFT 360 Query: 291 EEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD------ 344 +EE++ + + D + YYT+R K+ + L + + + + + Sbjct: 361 KEEQEKLASSCDIMGLNYYTSRFSKHVDMSPDFTPTLNTDDAYASSETTGSDGNDIGPIT 420 Query: 345 ---WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFP-----QSDPAPLDDTQRWEYFRQT 396 WIY+ P G+ LL +K+ Y NP ++ITENG +S P PLDD +R +Y ++ Sbjct: 421 GTYWIYMYPKGLTDLLLIMKEKYGNPPVFITENGIADVEGDESMPDPLDDWKRLDYLQRH 480 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 + AI +++ + W L+DNFEW+ GYSSRFGL ++D D + ++ SAK + Sbjct: 481 ISAVKDAID-QGADVRGHFTWGLIDNFEWSLGYSSRFGLVYIDKNDGNKRKLK-KSAKWF 538 Query: 457 AK 458 +K Sbjct: 539 SK 540 >3WQ4-A nrPDB Length = 507 Score = 307 bits (786), Expect = 7e-84, Method: Compositional matrix adjust. Identities = 180/485 (37%), Positives = 271/485 (55%), Gaps = 43/485 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 +FP GF + AA++AYQ EG GKGP +WDTFTH+ ++ TGDVA Y ++E Sbjct: 38 SFPDGFVFGAASSAYQFEGAAKEGGKGPNIWDTFTHEFPGKISNGSTGDVADDFYHRYKE 97 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D+K +K +GL +R S+SW+R+LP G +G +N++GI +YN +I+DLL G+ P +T++H Sbjct: 98 DVKVLKFIGLDGFRMSISWARVLPRGKLSGGVNKEGIAFYNNVINDLLSKGIQPFITIFH 157 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 +DLPQ LED+ GG+LS I+ F +A+ CF FGDRVK WIT+NE S YD G+ Sbjct: 158 WDLPQALEDEYGGFLSPHIVNDFRDFAELCFKEFGDRVKHWITMNEPWSYSYGGYDAGLL 217 Query: 180 PPG--------IP--HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 PG P + GT Y HNL+ +HA + Y ++ QKG + ++L W+ Sbjct: 218 APGRCSAFMAFCPKGNSGTEPYIVTHNLLLSHAAAVKLYKEKYQAYQKGQIGITLVTYWM 277 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 P NS +D++AA+RA+ F F +P+ G+YP+ ++ + RLP F Sbjct: 278 IPYS-NSKADKDAAQRALDFMYGWFIEPLSF-GEYPKSMRRLVG----------KRLPRF 325 Query: 290 TEEEKKMIKGTADFFAVQYYTTR-LIKYQENKKGELGILQDAEIEFFPDPSWKN------ 342 T+E+ ++KG+ DF + YY ++ + L D+ +++N Sbjct: 326 TKEQAMLVKGSFDFLGLNYYIANYVLNVPTSNSVNLSYTTDS---LSNQTAFRNGVAIGR 382 Query: 343 ---VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP----LDDTQRWEYFRQ 395 V ++ P G+ LL Y K+ YN+PVIYITENG ++ + D QR ++ Q Sbjct: 383 PTGVPAFFMYPKGLKDLLVYTKEKYNDPVIYITENGMGDNNNVTTEEGIKDPQRVYFYNQ 442 Query: 396 TFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 455 L AI V ++ Y W+ LDNFEW GY+ RFG+ +VDF+D + R P SA Sbjct: 443 HLLSLKNAIAAG-VKVKGYFTWAFLDNFEWLSGYTQRFGIVYVDFKDGLK-RYPKHSALW 500 Query: 456 YAKII 460 + K + Sbjct: 501 FKKFL 505 >1CBG-A nrPDB Length = 490 Score = 306 bits (785), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 188/486 (38%), Positives = 275/486 (56%), Gaps = 40/486 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 F GF + A++A+Q EG DGKGP +WDTFTH+ E++ GDVA Y ++E Sbjct: 18 CFAPGFVFGTASSAFQYEGAAFEDGKGPSIWDTFTHKYPEKIKDRTNGDVAIDEYHRYKE 77 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D+ +K + L YRFS+SW R+LP G +G +N++GI+YYN +I+++L NG+ P VTL+H Sbjct: 78 DIGIMKDMNLDAYRFSISWPRVLPKGKLSGGVNREGINYYNNLINEVLANGMQPYVTLFH 137 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 +D+PQ LED+ G+L I++ F YA+ CF FGDRVK WIT+NE +S+ +Y G F Sbjct: 138 WDVPQALEDEYRGFLGRNIVDDFRDYAELCFKEFGDRVKHWITLNEPWGVSMNAYAYGTF 197 Query: 180 PPG-----IPHFGTGG------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 PG + TGG Y AAH + AHA + Y + ++ Q G++ ++L + W Sbjct: 198 APGRCSDWLKLNCTGGDSGREPYLAAHYQLLAHAAAARLYKTKYQASQNGIIGITLVSHW 257 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 EPA +D +AAKR + F L F P+ G YPE ++ + RLP+ Sbjct: 258 FEPASKEK-ADVDAAKRGLDFMLGWFMHPL-TKGRYPESMRYLV----------RKRLPK 305 Query: 289 FTEEEKKMIKGTADFFAVQYYTTRL-IKYQENKKGELGILQDAEIEFFPDPSWKNV---- 343 F+ EE K + G+ DF + YY++ K I D+ I + + K + Sbjct: 306 FSTEESKELTGSFDFLGLNYYSSYYAAKAPRIPNARPAIQTDSLINATFEHNGKPLGPMA 365 Query: 344 --DWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQ-SDPA-----PLDDTQRWEYFRQ 395 W+ + P G+ KLL Y+K+ YNNPVIYITENG + +DP L DT R +Y+ + Sbjct: 366 ASSWLCIYPQGIRKLLLYVKNHYNNPVIYITENGRNEFNDPTLSLQESLLDTPRIDYYYR 425 Query: 396 TFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 455 + AI D VN++ Y AWSL DN EW+ GY+ RFGL VDF++ + R P SA Sbjct: 426 HLYYVLTAIG-DGVNVKGYFAWSLFDNMEWDSGYTVRFGLVFVDFKNNLK-RHPKLSAHW 483 Query: 456 YAKIIR 461 + ++ Sbjct: 484 FKSFLK 489 >5IDI-A nrPDB Length = 452 Score = 306 bits (784), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 178/472 (37%), Positives = 270/472 (57%), Gaps = 42/472 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W ATA+YQ+EG ADG G +W TF+H G V TGDVAC Y W+ED Sbjct: 4 FPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGN-VKNGDTGDVACDHYNRWKED 62 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ I+++G YRFS+SW R+LP+GT G +NQKG+D+YN+IID LL+ +TP +T+YH+D Sbjct: 63 IEIIEKIGAKAYRFSISWPRILPEGT-GKVNQKGLDFYNRIIDTLLEKNITPFITIYHWD 121 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LP +L+ +GGW + I + F +Y++ F FGDRVK WIT+NE V++++ + G+ PG Sbjct: 122 LPFSLQLKGGWANRDIADWFAEYSRVLFENFGDRVKHWITLNELWVVAIVGHLYGVHAPG 181 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQK-GMVSLSLFAVWLEPADPNSVSDQE 241 + + HNL++AHA+S +FR+ K G + + + EPA S++E Sbjct: 182 MKDIYV-AFHTVHNLLRAHAKS----VKVFRETVKDGKIGIVFNNGYFEPA-----SERE 231 Query: 242 AAKRAITFHLDLFAKPIFID----GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMI 297 RA F P+F++ G+YP++V + LP E++ + I Sbjct: 232 EDIRAARFMHQFNNYPLFLNPIYRGEYPDLVLE----------FAREYLPRNYEDDMEEI 281 Query: 298 KGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLL 357 K DF + YY+ ++KY N + ++ P + + W +VP G+ +L Sbjct: 282 KQEIDFVGLNYYSGHMVKYDPNSPARVSFVERN----LPKTA---MGW-EIVPEGIYWIL 333 Query: 358 KYIKDTYNNPVIYITENGFP----QSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQV 413 K +K+ YN +YIT NG S+ + D R +Y R +++++AIQ D V L+ Sbjct: 334 KGVKEEYNPQEVYITGNGAAFDDVVSEGGKVHDQNRIDYLRAHIEQVWRAIQ-DGVPLKG 392 Query: 414 YCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 Y WSLLDNFEW +GYS RFG+ +VD+ + R+ S Y+ +I+NNGL Sbjct: 393 YFVWSLLDNFEWAEGYSKRFGIVYVDYN--TQKRIIKDSGYWYSNVIKNNGL 442 >1QOX-A nrPDB Length = 449 Score = 296 bits (758), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 176/470 (37%), Positives = 259/470 (55%), Gaps = 32/470 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP+ F W ATAAYQ+EG ++ DG+G +WDTF H G +V G+VAC SY EED Sbjct: 5 FPSDFKWGVATAAYQIEGAYNEDGRGMSIWDTFAHTPG-KVKNGDNGNVACDSYHRVEED 63 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +K LG+ YRFS+SW R+LP GT G +N+ G+DYY++++D+LL NG+ P TLYH+D Sbjct: 64 VQLLKDLGVKVYRFSISWPRVLPQGT-GEVNRAGLDYYHRLVDELLANGIEPFCTLYHWD 122 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L+DQGGW S I++F +YA+ F G ++KQWIT NE ++ +S LG+ PG Sbjct: 123 LPQALQDQGGWGSRITIDAFAEYAELMFKELGGKIKQWITFNEPWCMAFLSNYLGVHAPG 182 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQ-KGMVSLSLFAVWLEPADPNSVSDQE 241 +H+L+ AH R+ +LFR+ G + ++ W P + D E Sbjct: 183 NKDLQL-AIDVSHHLLVAHGRA----VTLFRELGISGEIGIAPNTSWAVPYR-RTKEDME 236 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 A R + D + PI+ G+YP+ + ++ K P + + ++I Sbjct: 237 ACLRVNGWSGDWYLDPIYF-GEYPKFMLDWYENLGYK--------PPIVDGDMELIHQPI 287 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDW-IYVVPWGVCKLLKYI 360 DF + YYT+ + +Y + G G+L I + ++ W IY G+ LL+Y Sbjct: 288 DFIGINYYTSSMNRYNPGEAG--GMLSSEAISMGAPKT--DIGWEIYAE--GLYDLLRYT 341 Query: 361 KDTYNNPVIYITENGFPQSDPAPLD----DTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 D Y NP +YITENG +D LD D +R +Y + +AI+ D +NL+ Y Sbjct: 342 ADKYGNPTLYITENGACYNDGLSLDGRIHDQRRIDYLAMHLIQASRAIE-DGINLKGYME 400 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 WSL+DNFEW +GY RFGL HVD++ R P S Y +I L+ Sbjct: 401 WSLMDNFEWAEGYGMRFGLVHVDYDTLV--RTPKDSFYWYKGVISRGWLD 448 >1V02-A nrPDB Length = 565 Score = 295 bits (756), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 175/469 (37%), Positives = 258/469 (55%), Gaps = 44/469 (9%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + AAT+AYQ+EG W+ DGKGP WD F H E + GDVA SY ++ ED Sbjct: 76 FPPSFLFGAATSAYQIEGAWNEDGKGPSTWDHFCHNFPEWIVDRSNGDVAADSYHMYAED 135 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 ++ +K++G+ YRFS+SW R+LP GT G IN+K ++YYNK+ID LL+NG+ P +T++H+ Sbjct: 136 VRLLKEMGMDAYRFSISWPRILPKGTLAGGINEKRVEYYNKLIDLLLENGIEPYITIFHW 195 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 D PQ L D GG+L E II+ + +A+ CF FG VK W+T NE +SY G+ Sbjct: 196 DTPQALVDAYGGFLDERIIKDYTDFAKVCFEKFGKTVKNWLTFNEPETFCSVSYGTGVLA 255 Query: 181 PGIPHFG------TGG-----YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 PG G TG Y AHNL++AHA + Y+ + K G + L+L Sbjct: 256 PGRCSPGVSCAVPTGNSLSEPYIVAHNLLRAHAETVDIYNK-YHKGADGRIGLALNVFGR 314 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 P N+ DQ+A +R++ L F +P+ + GDYP ++ R+P F Sbjct: 315 VPYT-NTFLDQQAQERSMDKCLGWFLEPV-VRGDYPFSMRVSA----------RDRVPYF 362 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQD-----AEIEFFPD-----PS 339 E+E++ + G+ D + YYT+ K+ + +L ++ PD P Sbjct: 363 KEKEQEKLVGSYDMIGINYYTSTFSKHIDLSPNNSPVLNTDDAYASQETKGPDGNAIGPP 422 Query: 340 WKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD------PAPLDDTQRWEYF 393 N WI + P G+ +L +K+ Y NP +YITENG D P L+D R +Y Sbjct: 423 TGNA-WINMYPKGLHDILMTMKNKYGNPPMYITENGMGDIDKGDLPKPVALEDHTRLDYI 481 Query: 394 RQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFED 442 ++ L ++I L +++ Y AWSLLDNFEW+ GY+ RFG+ +VD E+ Sbjct: 482 QRHLSVLKQSIDLG-ADVRGYFAWSLLDNFEWSSGYTERFGIVYVDREN 529 >5JBO-A nrPDB Length = 485 Score = 294 bits (753), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 181/477 (37%), Positives = 252/477 (52%), Gaps = 38/477 (7%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 ++ P F W ATAAYQ+EG G+GP +WDT+ H R GDVAC Y ++ Sbjct: 6 LSLPKDFEWGFATAAYQIEGAVKEGGRGPSIWDTYCHLEPSRT-NGANGDVACDHYHRYD 64 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLP-DGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 ED + + G YRFSLSWSR++P G IN++GI +Y+ +ID LLK GVTP VTLY Sbjct: 65 EDFDLLTKYGAKAYRFSLSWSRIIPLGGRLDPINEEGIQFYSNLIDALLKRGVTPWVTLY 124 Query: 120 HFDLPQTLEDQ-GGWLSEAIIE-SFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLG 177 H+DLPQ L D+ GGWL+ ++ F++YA+ CF FGDRVK WITINE + S+ Y G Sbjct: 125 HWDLPQALHDRYGGWLNVKEVQLDFERYARLCFERFGDRVKNWITINEPWIQSIYGYATG 184 Query: 178 MFPPG---IPHFGTGG------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 PG I T G + A I +HAR+ Y FR QKG + +SL + Sbjct: 185 SNAPGRSSINKHSTEGDTTTEPWLAGKAQIMSHARAVAVYSKDFRASQKGQIGISLNGDY 244 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 EP D + D+EAA+R + FH+ +A PIF+ DYP ++ Q+ RLP Sbjct: 245 YEPWDSSDPRDKEAAERRMEFHIGWYANPIFLKKDYPASMRKQLG----------DRLPA 294 Query: 289 FTEEEKKMIK-GTADFFAVQYYTTRLIKYQEN---KKGELGILQDAE--IEFFPDPSWKN 342 T + ++ G DF+ + YYT++ ++ E K LG + + + + P Sbjct: 295 LTPADFAILNAGETDFYGMNYYTSQFARHYEGPVPKTDFLGAIHEHQENKDGSPVGEESG 354 Query: 343 VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFP------QSDPAPLDDTQRWEYFRQT 396 + W+ P K L + Y P IYITENG P + ++D R +YF Sbjct: 355 IFWLRSCPDMFRKHLARVHGLYGKP-IYITENGCPCPGEDKMTCEEAINDPFRIQYFDSH 413 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSA 453 + KAI D V ++ Y AW+LLDN EW+ GY RFG+ + D+ R P SA Sbjct: 414 LDSISKAISQDGVVVKGYFAWALLDNLEWSDGYGPRFGVTYTDYT--TLKRTPKKSA 468 >4MDP-A nrPDB Length = 499 Score = 293 bits (751), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 176/478 (36%), Positives = 258/478 (53%), Gaps = 39/478 (8%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 M+ P F W ATAAYQ+EG + DG+GP +WDTF G ++ +G VAC SY + Sbjct: 24 MSLPPDFKWGFATAAYQIEGSVNEDGRGPSIWDTFCAIPG-KIADGSSGAVACDSYKRTK 82 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLP-DGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 ED+ +K+LG YRFS+SWSR++P G INQKGID+Y K +DDL++ G+TP +TL+ Sbjct: 83 EDIALLKELGANSYRFSISWSRIIPLGGRNDPINQKGIDHYVKFVDDLIEAGITPFITLF 142 Query: 120 HFDLPQTLEDQ-GGWLS-EAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLG 177 H+DLP L+ + GG+L+ E F+ YA+ F + K WIT NE +++ Y+ G Sbjct: 143 HWDLPDALDKRYGGFLNKEEFAADFENYARIMFKAI-PKCKHWITFNEPWCSAILGYNTG 201 Query: 178 MFPPG---------IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 F PG + + HN++ AHAR+ +Y F+ Q G + ++L Sbjct: 202 YFAPGHTSDRSKSPVGDSAREPWIVGHNILIAHARAVKAYREDFKPTQGGEIGITLNGDA 261 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 P DP +D EA R I F + FA PI+ G YP+ ++ Q+ RLPE Sbjct: 262 TLPWDPEDPADIEACDRKIEFAISWFADPIYF-GKYPDSMRKQLGD----------RLPE 310 Query: 289 FTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPD------PSWKN 342 FT EE ++KG+ DF+ + +YT IK++ E L + E F+ P ++ Sbjct: 311 FTPEEVALVKGSNDFYGMNHYTANYIKHKTGVPPEDDFLGNLETLFYNKYGDCIGPETQS 370 Query: 343 VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENG--FPQSDPAPLD----DTQRWEYFRQT 396 W+ G LL ++ Y P IY+TENG + PL+ D R +YF Sbjct: 371 F-WLRPHAQGFRDLLNWLSKRYGYPKIYVTENGTSLKGENDMPLEQVLEDDFRVKYFNDY 429 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 + + A+ D N++ Y AWSLLDNFEW +GY +RFG+ +VD+ + + R P SAK Sbjct: 430 VRAMAAAVAEDGCNVRGYLAWSLLDNFEWAEGYETRFGVTYVDYANDQK-RYPKKSAK 486 >4HZ6-A nrPDB Length = 444 Score = 293 bits (751), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 176/469 (37%), Positives = 261/469 (55%), Gaps = 35/469 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W AAT++YQ+EG W+ DGKG +WD FT G ++ +GDVAC Y +E+D Sbjct: 5 FPEGFLWGAATSSYQIEGAWNEDGKGESIWDRFTRIPG-KIKNGDSGDVACDHYHRYEQD 63 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 L ++QLGL YRFS++W+R+ PD + INQ+G+D+Y ++++ L K + P+ TLYH+D Sbjct: 64 LDLMRQLGLKTYRFSIAWARIQPDSSRQ-INQRGLDFYRRLVEGLHKRDILPMATLYHWD 122 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ +ED+GGWLS F +Y + GD++ W+T NE V Y +G+F PG Sbjct: 123 LPQWVEDEGGWLSRESASRFAEYTHALVAALGDQIPLWVTHNEPMVTVWAGYHMGLFAPG 182 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + GG + AH+L+ +H ++ ++ +L + ++L+ ++ A+P +D EA Sbjct: 183 LKDPTLGG-RVAHHLLLSHGQALQAFRALSPAGSQMGITLNFNTIYPVSAEP---ADVEA 238 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF-TEEEKKMIKGTA 301 A+R +F +LF +P+ I G Y +Q M+ YP+ LPEF E+ + I Sbjct: 239 ARRMHSFQNELFLEPL-IRGQY-----NQATLMA----YPN--LPEFIAPEDMQTISAPI 286 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIK 361 DF V YY +K G + ++ + W+ + P G+ LL I Sbjct: 287 DFLGVNYYNPMRVKSSPQPPGIEVVQVESPVTAM---GWE------IAPEGLYDLLMGIT 337 Query: 362 DTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 TY IYITENG D ++D QR YF+ +A+ D V+L+ Y AW Sbjct: 338 RTYGKLPIYITENGAAFDDQPDQSGQVNDPQRVGYFQGHIGAARRALA-DGVDLRGYYAW 396 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 SLLDNFEW +GYS RFG+ +VDFE + R SA+ Y +I NNGLE Sbjct: 397 SLLDNFEWAEGYSKRFGIIYVDFE--TQQRTLKQSAQWYRDVIANNGLE 443 >5OGZ-A nrPDB Length = 456 Score = 290 bits (742), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 172/470 (36%), Positives = 263/470 (55%), Gaps = 30/470 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F W +ATAAYQ+EG ++ DGKG +WD F+H G + TGDVAC Y +E Sbjct: 4 ITFPKDFIWGSATAAYQIEGAYNEDGKGESIWDRFSHTPG-NIADGHTGDVACDHYHRYE 62 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED+K +K++G+ YRFS+SW R+ P+GT G +NQKG+D+Y ++ + LL+NG+ P +TLYH Sbjct: 63 EDIKIMKEIGIKSYRFSISWPRIFPEGT-GKLNQKGLDFYKRLTNLLLENGIMPAITLYH 121 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ L+D+GGW + + F +Y++ F GD V W T NE V+S++ + LG+ Sbjct: 122 WDLPQKLQDKGGWKNRDTTDYFTEYSEVIFKNLGDIVPIWFTHNEPGVVSLLGHFLGIHA 181 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQ-KGMVSLSLFAVWLEPADPNSVSD 239 PGI T + +HNL+ +H ++ LFR+ + ++L + PA + D Sbjct: 182 PGIKDLRT-SLEVSHNLLLSHGKAV----KLFREMNIDAQIGIALNLSYHYPASEKA-ED 235 Query: 240 QEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKG 299 EAA+ + + + P+ + G YPE + +K+G S F E++ K+I Sbjct: 236 IEAAELSFSLAGRWYLDPV-LKGRYPE----NALKLYKKKGIELS----FPEDDLKLISQ 286 Query: 300 TADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKY 359 DF A Y++ IKY + + ++ +E F ++ WI + P G+ LL Sbjct: 287 PIDFIAFNNYSSEFIKYDPSSESGFSP-ANSILEKFEK---TDMGWI-IYPEGLYDLLML 341 Query: 360 IKDTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYC 415 + Y P I I+ENG D ++DT+R +Y + + +AIQ D VNL+ Y Sbjct: 342 LDRDYGKPNIVISENGAAFKDEIGSNGKIEDTKRIQYLKDYLTQAHRAIQ-DGVNLKAYY 400 Query: 416 AWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 WSLLDNFEW GY+ RFG+ HV+F+ R S Y ++I+NNG Sbjct: 401 LWSLLDNFEWAYGYNKRFGIVHVNFD--TLERKIKDSGYWYKEVIKNNGF 448 >5BWF-A nrPDB Length = 485 Score = 286 bits (733), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 170/466 (36%), Positives = 249/466 (53%), Gaps = 29/466 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 P F W ATAAYQ+EG D DG+GP +WDTF G ++ +G AC SY ED Sbjct: 22 LPKDFQWGFATAAYQIEGAIDKDGRGPSIWDTFCAIPG-KIADGTSGVTACDSYNRTAED 80 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDG-TTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + +K LG YRFS+SWSR++P G +NQ GID+Y + +DDLL+ G+TP +TL+H+ Sbjct: 81 IALLKSLGAKSYRFSISWSRIIPKGGRDDPVNQLGIDHYAQFVDDLLEAGITPFITLFHW 140 Query: 122 DLPQTLEDQ-GGWLSEAIIE-SFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 DLP+ L + GG L+ F+ YA+ F +V+ WIT NE ++ Y G F Sbjct: 141 DLPEELHQRYGGLLNRTEFPLDFENYARVMFKAL-PKVRNWITFNEPLCSAIPGYGSGTF 199 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSD 239 PG T + HNL+ AH R+ Y F+ G + + L + P D + D Sbjct: 200 APG-RQSTTEPWIVGHNLLVAHGRAVKVYRDEFKDLNDGQIGIVLNGDFTYPWDSSDPLD 258 Query: 240 QEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKG 299 +EAA+R + F +A PI++ GDYP ++ Q+ RLPEFT EEK + G Sbjct: 259 REAAERRLEFFTAWYADPIYL-GDYPASMRKQLGD----------RLPEFTPEEKAFVLG 307 Query: 300 TADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSW-----KNVDWIYVVPWGVC 354 + DF+ + +YT+ I+++ + + + ++ F+ W+ P G Sbjct: 308 SNDFYGMNHYTSNYIRHRTSPATADDTVGNVDVLFYNKEGQCIGPETESSWLRPCPAGFR 367 Query: 355 KLLKYIKDTYNNPVIYITENG--FPQSDPAP----LDDTQRWEYFRQTFQELFKAIQLDK 408 L +I YN P IY+TENG + P L+D R Y+ + + +F A LD Sbjct: 368 DFLVWISKRYNYPKIYVTENGTSLKGENDLPKEKILEDDFRVNYYNEYIRAMFTAATLDG 427 Query: 409 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 VN++ Y AWSL+DNFEW GY +RFG+ +VD+E+ + R P SAK Sbjct: 428 VNVKGYFAWSLMDNFEWADGYVTRFGVTYVDYEN-GQQRFPKKSAK 472 >3AHY-A nrPDB Length = 473 Score = 283 bits (725), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 169/468 (36%), Positives = 255/468 (54%), Gaps = 32/468 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 P F W ATAAYQ+EG D DG+GP +WDTF Q G ++ +G AC SY ED Sbjct: 9 LPKDFQWGFATAAYQIEGAVDQDGRGPSIWDTFCAQPG-KIADGSSGVTACDSYNRTAED 67 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTG-FINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + +K LG YRFS+SWSR++P+G G +NQ GID+Y K +DDLL G+TP +TL+H+ Sbjct: 68 IALLKSLGAKSYRFSISWSRIIPEGGRGDAVNQAGIDHYVKFVDDLLDAGITPFITLFHW 127 Query: 122 DLPQTLEDQ-GGWLSEAIIE-SFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 DLP+ L + GG L+ F+ YA+ F +V+ WIT NE ++ Y G F Sbjct: 128 DLPEGLHQRYGGLLNRTEFPLDFENYARVMFRAL-PKVRNWITFNEPLCSAIPGYGSGTF 186 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQ-KGMVSLSLFAVWLEPADPNSVS 238 PG + + HN++ AH R+ +Y F+ G + + L + P D + Sbjct: 187 APGR-QSTSEPWTVGHNILVAHGRAVKAYRDDFKPASGDGQIGIVLNGDFTYPWDAADPA 245 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298 D+EAA+R + F FA PI++ GDYP ++ Q+ RLP FT EE+ ++ Sbjct: 246 DKEAAERRLEFFTAWFADPIYL-GDYPASMRKQLGD----------RLPTFTPEERALVH 294 Query: 299 GTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPD------PSWKNVDWIYVVPWG 352 G+ DF+ + +YT+ I+++ + + + ++ F P ++ W+ G Sbjct: 295 GSNDFYGMNHYTSNYIRHRSSPASADDTVGNVDVLFTNKQGNCIGPETQS-PWLRPCAAG 353 Query: 353 VCKLLKYIKDTYNNPVIYITENGFP---QSD---PAPLDDTQRWEYFRQTFQELFKAIQL 406 L +I Y P IY+TENG +SD L+D R +Y+ + + + A++L Sbjct: 354 FRDFLVWISKRYGYPPIYVTENGTSIKGESDLPKEKILEDDFRVKYYNEYIRAMVTAVEL 413 Query: 407 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 D VN++ Y AWSL+DNFEW GY +RFG+ +VD+E+ + R P SAK Sbjct: 414 DGVNVKGYFAWSLMDNFEWADGYVTRFGVTYVDYEN-GQKRFPKKSAK 460 >1BGG-A nrPDB Length = 448 Score = 283 bits (725), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 173/473 (36%), Positives = 258/473 (54%), Gaps = 40/473 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W ATAAYQ+EG + DG+G +WDTF H G +VF G+VAC SY +EED Sbjct: 6 FPQDFMWGTATAAYQIEGAYQEDGRGLSIWDTFAHTPG-KVFNGDNGNVACDSYHRYEED 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +K+LG+ YRFS+SW R+ P+G G +NQ+G+DYY++++D L NG+ P TLYH+D Sbjct: 65 IRLMKELGIRTYRFSVSWPRIFPNGD-GEVNQEGLDYYHRVVDLLNDNGIEPFCTLYHWD 123 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L+D GGW + I++F ++A+ F F +++ W+T NE ++ +S LG+ PG Sbjct: 124 LPQALQDAGGWGNRRTIQAFVQFAETMFREFHGKIQHWLTFNEPWCIAFLSNMLGVHAPG 183 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVS--DQ 240 + + T H+L+ AH S + L Q G+ +AV P S S D+ Sbjct: 184 LTNLQT-AIDVGHHLLVAHGLSVRRFRELGTSGQIGIAPNVSWAV------PYSTSEEDK 236 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 A R I+ H D F +PI+ G YP+ + A +QG + +P + + +I Sbjct: 237 AACARTISLHSDWFLQPIY-QGSYPQFLVDWFA----EQG---ATVP-IQDGDMDIIGEP 287 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEF---FPDPSWKNVDWIYVVPWGVCKLL 357 D + YY+ + ++ E G LQ EI D W V G+ ++L Sbjct: 288 IDMIGINYYSMSVNRFNP----EAGFLQSEEINMGLPVTDIGWP------VESRGLYEVL 337 Query: 358 KYIKDTYNNPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVY 414 Y++ Y N IYITENG +D + D +R Y +Q ++ + I D ++++ Y Sbjct: 338 HYLQ-KYGNIDIYITENGACINDEVVNGKVQDDRRISYMQQHLVQVHRTIH-DGLHVKGY 395 Query: 415 CAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 AWSLLDNFEW +GY+ RFG+ HVDF + R P S Y ++ NN LE Sbjct: 396 MAWSLLDNFEWAEGYNMRFGMIHVDFR--TQVRTPKESYYWYRNVVSNNWLET 446 >1E55-A nrPDB Length = 512 Score = 281 bits (720), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 170/470 (36%), Positives = 256/470 (54%), Gaps = 47/470 (10%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP+ F + AAT+AYQ+EG W+ DGKG WD F H ER+ D+ SY +++ D Sbjct: 24 FPSDFTFGAATSAYQIEGAWNEDGKGESNWDHFCHNHPERILDGSNSDIGANSYHMYKTD 83 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTT-GFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 ++ +K++G+ YRFS+SW R+LP GT G IN GI YY +I+ LL+NG+ P VT++H+ Sbjct: 84 VRLLKEMGMDAYRFSISWPRILPKGTKEGGINPDGIKYYRNLINLLLENGIEPYVTIFHW 143 Query: 122 DLPQTLEDQ-GGWLS---EAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLG 177 D+PQ LE++ GG+L ++I+E + +A+ CF FGD+VK W+T N+ + SY G Sbjct: 144 DVPQALEEKYGGFLDKSHKSIVEDYTYFAKVCFDNFGDKVKNWLTFNDPQTFTSFSYGTG 203 Query: 178 MFPPGIPHFG------TGG-----YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226 +F PG G TG Y A HN++ AHA + Y+ + K+ + L+ Sbjct: 204 VFAPGRCSPGLDCAYPTGNSLVEPYTAGHNILLAHAEAVDLYNKHY-KRDDTRIGLAFDV 262 Query: 227 VWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRL 286 + P S D++A +R+ +L F +P+ + GDYP ++S RL Sbjct: 263 MGRVPYG-TSFLDKQAEERSWDINLGWFLEPV-VRGDYPFSMRS----------LARERL 310 Query: 287 PEFTEEEKKMIKGTADFFAVQYYTTRL---IKYQENKKGELGILQDAEIEFFPDPSWKNV 343 P F +E+K+ + G+ + + YYT+R I N L + P K + Sbjct: 311 PFFKDEQKEKLAGSYNMLGLNYYTSRFSKNIDISPNYSPVLNTDDAYASQEVNGPDGKPI 370 Query: 344 D------WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD----PAP----LDDTQR 389 WIY+ P G+ LL +K+ Y NP IYITENG D P P L+D +R Sbjct: 371 GPPMGNPWIYMYPEGLKDLLMIMKNKYGNPPIYITENGIGDVDTKETPLPMEAALNDYKR 430 Query: 390 WEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVD 439 +Y ++ L ++I L N+Q Y AWSLLDNFEW G++ R+G+ +VD Sbjct: 431 LDYIQRHIATLKESIDLGS-NVQGYFAWSLLDNFEWFAGFTERYGIVYVD 479 >4PTW-A nrPDB Length = 452 Score = 269 bits (687), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 164/479 (34%), Positives = 259/479 (54%), Gaps = 42/479 (8%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F W AAT++YQ+EG ++ DGKG +WD F+H G ++ TGD+AC Y L+ Sbjct: 5 IIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPG-KIENGDTGDIACDHYHLYR 63 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ +K++G+ YRFS SW R+LP+G G +NQKG+D+Y +++D+LLK + P++TLYH Sbjct: 64 EDIELMKEIGIRSYRFSTSWPRILPEGK-GRVNQKGLDFYKRLVDNLLKANIRPMITLYH 122 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ L+D+GGW + + F +YA+ F F V W+T NE V++ + G Sbjct: 123 WDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDLWVTHNEPWVVAFEGHAFGNHA 182 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQ-KGMVSLSLFAVWLEPADP--NSV 237 PG F T Q AH+L+ +H + +FR++ G + ++L L PA P +S Sbjct: 183 PGTKDFKT-ALQVAHHLLLSHGMAV----DIFREEDLPGEIGITLN---LTPAYPAGDSE 234 Query: 238 SDQEAAKRAITFHLDLFAKPIFIDGDYPE----VVKSQIASMSQKQGYPSSRLPEFTEEE 293 D +AA + F P+F G YPE + + + + + + G + Sbjct: 235 KDVKAASLLDDYINAWFLSPVF-KGSYPEELHHIYEQNLGAFTTQPG------------D 281 Query: 294 KKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGV 353 +I DF + YY+ +++++ L +AE+ D + W + P G+ Sbjct: 282 MDIISRDIDFLGINYYSRMVVRHKPGDN-----LFNAEVVKMEDRPSTEMGW-EIYPQGL 335 Query: 354 CKLLKYIKDTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKAIQLDKV 409 +L + Y + +YITENG D + D +R Y F++ +KA++ D V Sbjct: 336 YDILVRVNKEYTDKPLYITENGAAFDDKLTEEGKIHDEKRINYLGDHFKQAYKALK-DGV 394 Query: 410 NLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 468 L+ Y WSL+DNFEW GYS RFGL +VD+E+ R R SA Y ++I +EA+ Sbjct: 395 PLRGYYVWSLMDNFEWAYGYSKRFGLIYVDYENGNR-RFLKDSALWYREVIEKGQVEAN 452 >3AHX-A nrPDB Length = 453 Score = 266 bits (679), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 172/471 (36%), Positives = 253/471 (53%), Gaps = 32/471 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F + ATAAYQ+EG + D KG +WD F+H G V K GD+AC Y ++ Sbjct: 4 LRFPKDFIFGTATAAYQIEGAYKEDEKGESIWDRFSHIPG-NVAKMHNGDIACDHYHRYK 62 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ +K LG+ YRFS++W R+ P G G INQKGI +Y +ID+L+KN + P +T+YH Sbjct: 63 EDVQLLKSLGIKSYRFSIAWPRIFPKGF-GEINQKGIQFYRDLIDELIKNDIEPAITIYH 121 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ L+D GGW + + + + YA F FGDRVK WIT NE V S + Y LG+ Sbjct: 122 WDLPQKLQDIGGWANPQVADYYVDYANLLFREFGDRVKTWITHNEPWVASYLGYALGVHA 181 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGI AAHN++ +H ++ +Y L + Q G ++L+L + AD ++ Sbjct: 182 PGIKDMKM-ALLAAHNILLSHFKAVKAYRELEQDGQIG-ITLNLSTCYSNSADEEDIA-- 237 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 AA R+ ++ F + G YPE I S ++ +PE +E + T Sbjct: 238 -AAHRSDGWNNRWFLDAA-LKGTYPE---DMIKIFSD-----TNIMPELPKELFTEVFET 287 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 +DF + YYT +++K N + +G AE +P + W + P G+ LL I Sbjct: 288 SDFLGINYYTRQVVK--NNSEAFIG----AESVAMDNPK-TEMGW-EIYPQGLYDLLTRI 339 Query: 361 KDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 Y N +YITENG +D ++D R +Y F AI+ V L+ Y Sbjct: 340 HRDYGNIDLYITENGAAFNDMVNRDGKVEDENRLDYLYTHFAAALSAIEA-GVPLKGYYI 398 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII-RNNGLE 466 WS +DNFEW +GY RFG+ HV+++ + R SA Y ++I R+N LE Sbjct: 399 WSFMDNFEWAEGYEKRFGIVHVNYK--TQERTIKKSAYWYKELIERSNKLE 447 >5XGZ-A nrPDB Length = 457 Score = 260 bits (665), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 160/470 (34%), Positives = 248/470 (52%), Gaps = 33/470 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W AT++YQ+EG +ADG+ P +WDTF + G + TG +A Y + ED Sbjct: 10 FPPDFQWGVATSSYQIEGAVEADGRSPSIWDTFCARPGA-IADGSTGAIANDHYHRYRED 68 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + +KQLG+ YRFS++W R+LPDG G +NQ G+D+Y +++D LL+ G+ P TLYH+D Sbjct: 69 IAIMKQLGVNAYRFSIAWPRILPDGR-GRVNQAGVDFYERLVDSLLEQGIEPYATLYHWD 127 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 +PQ D+ W ++++F +Y DRVK W+T+NE V+S + Y G PG Sbjct: 128 MPQVQHDRTPWYDRGVVDAFVEYTDVITRRLSDRVKYWMTLNEPWVISFLGYGAGEHAPG 187 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + +AAH+++ AH ++ + + K + L+L W+ A +S DQ A Sbjct: 188 L-RDKELYLRAAHHVLLAHGKAMPVIRANGNAQTKAGIVLNL--NWVNAAS-DSPEDQAA 243 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A+R F FA+P++ +G YPE + + Y +P + +I D Sbjct: 244 ARRYDQFFNRWFAEPLY-NGRYPEEL---------LEWYGRDLVP-VQPGDFDIITTPTD 292 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPS-WKNVDWIYVVPWGVCKLLKYIK 361 F AV YY +K +LQ ++F P + +DW V P G+ +L ++ Sbjct: 293 FLAVNYYARTTVKAGSTDP----MLQ---VDFVRPPGEYTAMDW-EVYPQGLYNILNWLH 344 Query: 362 DTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 Y P +Y+TENG D +DD QR Y F+ ++AIQ + L+ Y W Sbjct: 345 TDYAPPALYVTENGAAYDDQVSAAGEVDDPQRLAYLEGHFEAAYRAIQA-GIPLKGYFVW 403 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 SL+DNFEW +G+ RFG+ VD+ + R+ S K ++++ R NGL A Sbjct: 404 SLMDNFEWGRGFEKRFGIVFVDYA--TQQRIIKRSGKWFSQVTRANGLPA 451 >5YHS-A nrPDB Length = 475 Score = 257 bits (657), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 168/490 (34%), Positives = 257/490 (52%), Gaps = 46/490 (9%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 M FP F + AA+A+YQVEG W+ DGKG WD F+ G + + GD+A Y ++ Sbjct: 1 MKFPHDFLFGAASASYQVEGAWNEDGKGVTNWDEFSKIPG-KTYNGTNGDIAVDHYHRYK 59 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ + ++GL YRFS+SW+R+LP G G +N+KGI++YN +ID+ LK G+ P VTLYH Sbjct: 60 EDVRLMAEMGLESYRFSISWARILPTGD-GKVNEKGIEFYNNLIDECLKYGIVPFVTLYH 118 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLP LE GGW ++ E+F KYA+ CF FGDRVK WIT NE + + Y G P Sbjct: 119 WDLPLPLEKDGGWTNKRTAEAFVKYAETCFKAFGDRVKHWITFNETVMFCGLGYLKGAHP 178 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGI + +QA H + AHA++ Y L + + G+ + L A SV DQ Sbjct: 179 PGIQNDVPKYFQATHYVFYAHAKTVAVYKQLKQYGEIGITHVFLPAY--------SVDDQ 230 Query: 241 ----EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296 +AA A + + PI + G+YP V Q+ +++G+ P +T EE ++ Sbjct: 231 KENIQAANHANEYETYWYYDPI-LKGEYPSYVVQQL----KEKGW----TPNWTVEELEI 281 Query: 297 IKGTA---DFFAVQYYT-TRLIKYQENKKGELGILQDAEIE--------FF-----PDPS 339 IK A DF + YY R+ +Y + K E +++ + F+ D + Sbjct: 282 IKQNAEENDFIGLNYYQPIRVERYDMDIKSEEHSRENSTLAPGNPSFDGFYRTVKMDDKT 341 Query: 340 WKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDP---APLDDTQRWEYFRQT 396 + W + P G + L +K Y + +Y+TENG DP + D R ++ Sbjct: 342 YTKWGW-EISPEGFLEGLHMLKARYGDIKMYVTENGLGDEDPIIDGEIVDVPRIKFIEAH 400 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 + + +AI+ + +NL+ Y AWS++D W GY ++G VD D + R S Y Sbjct: 401 LKVMKRAIE-EGINLKGYYAWSVIDLLSWLNGYKKQYGFIFVDHNDNLK-RKKKLSFHWY 458 Query: 457 AKIIRNNGLE 466 +++ G E Sbjct: 459 KRVVETRGEE 468 >4ZEN-A nrPDB Length = 485 Score = 254 bits (650), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 170/489 (34%), Positives = 253/489 (51%), Gaps = 45/489 (9%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W AA+AAYQVEG W+ DGKG VWD F Q G R FK GDVA Y ++ED Sbjct: 16 FPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPG-RTFKGTNGDVAVDHYHRYQED 74 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + + ++GL YRFS+SWSR+ PDG G +N+KG+D+Y+++I++L +G+ PIVTLYH+D Sbjct: 75 VALMAEMGLKAYRFSVSWSRVFPDGN-GAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWD 133 Query: 123 LPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 +PQ L D G W S II+ FD+YA F FGDRVK W+T+NE N+ Y LG+ PP Sbjct: 134 VPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISFGYRLGLHPP 193 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADP---NSVS 238 G+ Y+A H A+A+ S+ G + S + P D N ++ Sbjct: 194 GVKDMKR-MYEANHIANLANAKVIQSFRHYV---PDGKIGPSFAYSPMYPYDSRPENVLA 249 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298 + A + + +D++A G YP+ + + S QG + P + + + Sbjct: 250 FENAEEFQNHWWMDVYAW-----GMYPQAAWNYLES----QGLEPTVAP---GDWELLQA 297 Query: 299 GTADFFAVQYYTTRLIKYQE---------NKKGELGILQDAEI----EFFPDPSWKNVDW 345 DF V YY T +++ N G+ G + I + +P +W Sbjct: 298 AKPDFMGVNYYQTTTVEHNPPDGVGEGVMNTTGKKGTSTSSGIPGLFKTVRNPHVDTTNW 357 Query: 346 IYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP----LDDTQRWEYFRQTFQEL 400 + + P G+ L+ I + Y P++ ITENG + D ++D R +Y R+ QE+ Sbjct: 358 DWAIDPVGLRIGLRRIANRYQLPIL-ITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEI 416 Query: 401 FKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP---RVPYTSAKEYA 457 +AI D V++ YCAWS D W GY R+G +V+ +D + R+ S Y Sbjct: 417 QRAIT-DGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQ 475 Query: 458 KIIRNNGLE 466 ++I NG E Sbjct: 476 RVIETNGAE 484 >2Z1S-A nrPDB Length = 454 Score = 248 bits (634), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 157/469 (33%), Positives = 242/469 (51%), Gaps = 34/469 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FPA F W +T++YQ+EGG D G+ P +WDTF G +V GDVAC + ++ED Sbjct: 14 FPATFMWGTSTSSYQIEGGTDEGGRTPSIWDTFCQIPG-KVIGGDCGDVACDHFHHFKED 72 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +KQLG HYRFS++W R++P G IN++G+ +Y ++D++ G+ P++TLYH+D Sbjct: 73 VQLMKQLGFLHYRFSVAWPRIMP--AAGIINEEGLLFYEHLLDEIELAGLIPMLTLYHWD 130 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ +ED+GGW I+ F YA FG+R+ W TINE S++ Y G PG Sbjct: 131 LPQWIEDEGGWTQRETIQHFKTYASVIMDRFGERINWWNTINEPYCASILGYGTGEHAPG 190 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSV--SDQ 240 ++ + AAH+++ H + + + K+KG+ + +E D S D Sbjct: 191 HENWRE-AFTAAHHILMCHGIASNLH------KEKGLTGKIGITLNMEHVDAASERPEDV 243 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 AA R F FA+P+F +G YPE M + G + L + ++I+ Sbjct: 244 AAAIRRDGFINRWFAEPLF-NGKYPE-------DMVEWYGTYLNGLDFVQPGDMELIQQP 295 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DF + YYT +I+ N L + Q E D W+ + P KLL I Sbjct: 296 GDFLGINYYTRSIIR-STNDASLLQVEQVHMEEPVTDMGWE------IHPESFYKLLTRI 348 Query: 361 KDTYNNPV-IYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 + ++ + I ITENG D ++DT R Y + + + I+ + L+ Y Sbjct: 349 EKDFSKGLPILITENGAAMRDELVNGQIEDTGRQRYIEEHLKACHRFIE-EGGQLKGYFV 407 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 WS LDNFEW GYS RFG+ H+++E + R P SA + +++ NG Sbjct: 408 WSFLDNFEWAWGYSKRFGIVHINYE--TQERTPKQSALWFKQMMAKNGF 454 >1W9D-M nrPDB Length = 501 Score = 246 bits (629), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 153/469 (32%), Positives = 238/469 (50%), Gaps = 54/469 (11%) Query: 10 AAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQ-TGDVACGSYTLWEEDLKCIKQ 68 A++AYQ+EG G+G +WD FTH+ + + GD C S++ W++D+ + + Sbjct: 32 GVASSAYQIEG---TIGRGLNIWDGFTHRYPNKSGPDHGNGDTTCDSFSYWQKDIDVLDE 88 Query: 69 LGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTL 127 L T YRFS++WSR++P G + +N+KGIDYY+ +I L+K G+TP VTL+H+DLPQTL Sbjct: 89 LNATGYRFSIAWSRIIPRGKRSRGVNEKGIDYYHGLISGLIKKGITPFVTLFHWDLPQTL 148 Query: 128 EDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG---- 182 +D+ G+L II+ F YA CF FGD VK W+TIN+ + Y + PG Sbjct: 149 QDEYEGFLDPQIIDDFKDYADLCFEEFGDSVKYWLTINQLYSVPTRGYGSALDAPGRCSP 208 Query: 183 -------IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKK---QKGMVSLSLFAVWLEPA 232 + T Y AH+ + AHA+ L+RK Q G + ++ W P Sbjct: 209 TVDPSCYAGNSSTEPYIVAHHQLLAHAKVV----DLYRKNYTHQGGKIGPTMITRWFLPY 264 Query: 233 DPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEE 292 + A +R F L F P+ +G YP+++ + RLP F+ E Sbjct: 265 NDTDRHSIAATERMKEFFLGWFMGPL-TNGTYPQIMIDTVG----------ERLPSFSPE 313 Query: 293 EKKMIKGTADFFAVQYYTTRLIKYQENKKGELG--ILQDAEIE-------------FFPD 337 E ++KG+ DF + YY T+ + N + DA + F Sbjct: 314 ESNLVKGSYDFLGLNYYFTQYAQPSPNPVNSTNHTAMMDAGAKLTYINASGHYIGPLFEK 373 Query: 338 PSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFP----QSDPAPLDDTQRWEYF 393 + D IY P G+ ++ Y K+ Y NP+IY+TENG ++ + D R +Y Sbjct: 374 DKADSTDNIYYYPKGIYSVMDYFKNKYYNPLIYVTENGISTPGDENRNQSMLDYTRIDYL 433 Query: 394 RQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFED 442 L K I+ VN++ Y AW+L DN+E+N+G++ RFGL ++D+ + Sbjct: 434 CSHLCFLNKVIKEKDVNVKGYLAWALGDNYEFNKGFTVRFGLSYIDWNN 482 >1GNX-A nrPDB Length = 479 Score = 242 bits (618), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 162/479 (33%), Positives = 236/479 (49%), Gaps = 32/479 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP GF W +ATA+YQ+EG DG+ P +WDT+ G RV TGDVA Y W Sbjct: 16 LTFPEGFLWGSATASYQIEGAAAEDGRTPSIWDTYARTPG-RVRNGDTGDVATDHYHRWR 74 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED+ + +LGL YRFSL+W R+ P G G QKG+D+Y ++ D+LL G+ P+ TLYH Sbjct: 75 EDVALMAELGLGAYRFSLAWPRIQPTGR-GPALQKGLDFYRRLADELLAKGIQPVATLYH 133 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ LE+ GGW A E F +YA GDRVK W T+NE + + Y G+ Sbjct: 134 WDLPQELENAGGWPERATAERFAEYAAIAADALGDRVKTWTTLNEPWCSAFLGYGSGVHA 193 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG +AAH+L H + + + V+L++ V P +S +D Sbjct: 194 PGRTD-PVAALRAAHHLNLGHGLAVQALRDRLPADAQCSVTLNIHHV--RPLT-DSDADA 249 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 +A +R +F P+ + G YPE + A ++ + R + +K+ Sbjct: 250 DAVRRIDALANRVFTGPM-LQGAYPEDLVKDTAGLTD---WSFVRDGDLRLAHQKL---- 301 Query: 301 ADFFAVQYYTTRLIKYQE-----NKKGELGILQDA-----EIEFFPDPSWKNVDWIYVVP 350 DF V YY+ L+ + N G + F P V P Sbjct: 302 -DFLGVNYYSPTLVSEADGSGTHNSDGHGRSAHSPWPGADRVAFHQPPGETTAMGWAVDP 360 Query: 351 WGVCKLLKYIKDTYNNPVIYITENG---FPQSDP-APLDDTQRWEYFRQTFQELFKAIQL 406 G+ +LL+ + + + ITENG +DP ++D +R Y R + +AI+ Sbjct: 361 SGLYELLRRLSSDFPALPLVITENGAAFHDYADPEGNVNDPERIAYVRDHLAAVHRAIK- 419 Query: 407 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 D +++ Y WSLLDNFEW GYS RFG +VD+ P R+P SA+ YA++ R L Sbjct: 420 DGSDVRGYFLWSLLDNFEWAHGYSKRFGAVYVDY--PTGTRIPKASARWYAEVARTGVL 476 >5GNX-A nrPDB Length = 467 Score = 241 bits (616), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 165/477 (34%), Positives = 243/477 (50%), Gaps = 52/477 (10%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W AATAAYQ+EG ADG G +WD F+H G + TGDVAC Y W ED Sbjct: 14 FPEGFLWGAATAAYQIEGSSMADGAGESIWDRFSHTPGN-MKDGDTGDVACDHYNRWRED 72 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +K+L L YRFS+SWSR++P G G IN KG+ +Y++++D LL+ G+ P+ TLYH+D Sbjct: 73 IELMKRLNLQAYRFSVSWSRVIPQGR-GAINPKGLAFYDRLVDGLLEAGIEPLATLYHWD 131 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LP L+D+GGWL+ I + F Y Q F F RVK W TIN+ V+ Y G PG Sbjct: 132 LPAALDDRGGWLNPDIADWFADYGQVLFEKFKGRVKTWGTINQPWVIVDGGYLHGALAPG 191 Query: 183 IPHFGTGGYQ---AAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNS-VS 238 Y+ A HN+++AH + FR+ +G + + L +EP P S Sbjct: 192 ----HRSAYEAVIAGHNVLRAHGAAVRR----FREVGEGQIGIVLN---IEPKYPASDKP 240 Query: 239 DQEAAKRAITFHLDL-FAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMI 297 + EAA+R ++ F P+ G YPE + + + EF +E+ ++I Sbjct: 241 EDEAARRRAEAQMNRWFLDPLMGRG-YPEELTDVYGAAWR----------EFPKEDFELI 289 Query: 298 KGTADFFAVQYYTTRLIKYQEN----KKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGV 353 D+ + +YT + + + + + Q A E W+ V P + Sbjct: 290 AEPTDWMGLNWYTRAVPENAPDAWPTRSRPVRQTQHAHTE----TGWE------VYPPAL 339 Query: 354 CKLLKYIKDTYNNPV-IYITENGFPQSDP-----APLDDTQRWEYFRQTFQELFKAIQLD 407 L ++ + + + +TENG DP + D R Y + + L AI Sbjct: 340 TDTLVWLSEQTGGKLPLMVTENGSAWYDPPHAIDGRIHDPMRVHYLQTHIKALHDAIG-K 398 Query: 408 KVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464 V+L+ Y AWSLLDN EW+ GYS RFG+ HV+F + R S YA++I+ +G Sbjct: 399 GVDLRGYMAWSLLDNLEWSLGYSKRFGIVHVNFA--TQERTIKDSGLLYAEVIKTHG 453 >5AYI-A nrPDB Length = 457 Score = 241 bits (614), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 158/444 (35%), Positives = 225/444 (50%), Gaps = 31/444 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FPA F W AATAAYQ+EG DG+G +WDTF+H G ++ TGDVAC SY + ED Sbjct: 6 FPADFVWGAATAAYQIEGAVREDGRGVSIWDTFSHTPG-KIADGTTGDVACDSYHRYGED 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + + LG+ YRFS++W R++P G G INQ G+D+Y++++D LL G+ P VTLYH+D Sbjct: 65 IGLLNALGMNAYRFSIAWPRIVPLGA-GPINQAGLDHYSRMVDALLGAGLQPFVTLYHWD 123 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ LED+ GW S A F +YA GDRV W T+NE +++ Y LG+ PG Sbjct: 124 LPQPLEDRLGWGSRATATVFAEYADIVVRQLGDRVTHWATLNEPWCSAMLGYYLGVHAPG 183 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 G +A+HNL+ H + + + + + + L L + PA +S D A Sbjct: 184 HTDLKR-GLEASHNLLLGHGLAVQAMRAAAPQPLQIGIVLQLTPTY--PAS-DSPEDVAA 239 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A+R F F P+ G YP+ + Y + P+ E+ I D Sbjct: 240 ARRFDGFVNRWFLDPLAGRG-YPQDMLD----------YYGAAAPQANPEDLTQIAAPLD 288 Query: 303 FFAVQYY-TTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIK 361 + V YY R + + + L D ++ D V P G+ +L + Sbjct: 289 WLGVNYYERMRAVDAPDASLPQAQRLDDPDLPHTADRE--------VYPEGLYDILLRLH 340 Query: 362 DTYNNPVIYITENGFPQSDPAPLD----DTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 + Y +YITENG D D D QR +F +L +A+ V L+ Y AW Sbjct: 341 NDYPFRPLYITENGCALHDEIAEDGGIHDGQRQAFFEAHLAQLQRALAA-GVPLKGYFAW 399 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFE 441 SLLDNFEW G S R+G+ + +FE Sbjct: 400 SLLDNFEWAMGLSMRYGICYTNFE 423 >3W53-A nrPDB Length = 506 Score = 228 bits (582), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 156/481 (32%), Positives = 235/481 (48%), Gaps = 41/481 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 A+P F W +ATAA Q+EG + GK VWD F + G + + +VA Y + E Sbjct: 44 AWPKEFLWGSATAAAQIEGAGHSYGKEDSVWDAFARKEGA-IAGGENLEVAVDHYHRYRE 102 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ +++LGL YRFS SW+R++P G T +N +G+D+Y++++D+LL+NG+ P +TLYH+ Sbjct: 103 DVQLMRELGLDSYRFSTSWARVVPGGRT--VNPEGLDFYSRLVDELLENGILPWLTLYHW 160 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLPQ LE++GGW + F +YA+ GDRVK W T NE S++ Y G P Sbjct: 161 DLPQALEERGGWTNRETSYKFLEYAETVHEKLGDRVKHWTTFNEPLCSSLIGYAAGEHAP 220 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G A H+ AH + + R+ + ++L P +P D E Sbjct: 221 GRQE-PQAALAAVHHQHLAHGLA----TARLRELGAEHIGITLNLTNAVPNNPGDPVDLE 275 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEE-EKKMIKGT 300 AA+R ++ P+ + G YPE + + + L E E + ++I Sbjct: 276 AARRVDALWNRMYLDPV-LRGSYPEDLLEDVQGLG---------LAEVIEAGDLEIISQP 325 Query: 301 ADFFAVQYYTTRLIKYQENKKGE-----------LGILQDAEIEFFP--DPSWKNVDWIY 347 DF V +Y + G+ +E FP D + W Sbjct: 326 IDFLGVNHYHDDNVSGHPLPAGQPQPVVPTDSPKSSPFVGSEYVTFPARDLPRTAMGW-E 384 Query: 348 VVPWGVCKLLKYIKDTYNN-PVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFK 402 V P G+ LL + Y N P +YITENG +D ++D +R EY + + Sbjct: 385 VNPEGLRVLLNRLNQDYANLPSLYITENGASYTDTVTEAGTVEDPEREEYILNHLDAVVR 444 Query: 403 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 AI D V+++ Y WSLLDNFEW GY+ RFG+ HVD++ + R S K YA +I Sbjct: 445 AIA-DGVDVRGYFVWSLLDNFEWAWGYAKRFGIIHVDYQ--TQVRTIKNSGKAYAGLIAA 501 Query: 463 N 463 N Sbjct: 502 N 502 >5NS7-A nrPDB Length = 454 Score = 226 bits (577), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 152/461 (32%), Positives = 235/461 (50%), Gaps = 33/461 (7%) Query: 7 FGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCI 66 F W +T++YQ+EG + G+GP +WDTF+ G V GDVAC Y + EDL + Sbjct: 23 FTWGVSTSSYQIEGAANQGGRGPSIWDTFSKIPGA-VANGDNGDVACDHYHRYNEDLDLM 81 Query: 67 KQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQT 126 K LG+ YRFS++W R++P G G +N++G+D+Y+++ID L+ G+TP TLYH+DLPQ+ Sbjct: 82 KWLGVGAYRFSIAWPRVIPSGY-GALNKEGMDFYDRLIDGALERGITPWPTLYHWDLPQS 140 Query: 127 LEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHF 186 L+D+GGW + F +Y+Q F DR+K WITINE + + + G+ PGI Sbjct: 141 LQDKGGWNNRDCAYWFAEYSQKMAEAFSDRLKNWITINEPFCSAWLGHLYGVMAPGIKDL 200 Query: 187 GTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRA 246 T G A+H+L+ H + + + + + G+ A+ L S D+ A + A Sbjct: 201 KT-GINASHHLLLGHGLATKAIREVSSELKVGITLNFTPAITLG----ESSEDKLAVELA 255 Query: 247 ITFHLDLFAKPIFIDGDYPE-VVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFA 305 F F P+F YPE +VK+ + G + ++I D+ Sbjct: 256 DGFDNRWFGDPVF-KAKYPEDIVKAFGKEVPIHPG------------DMEIISTPLDYLG 302 Query: 306 VQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYN 365 + YY + ++Y K L Q P+ + W V +LL+ + Y Sbjct: 303 LNYYFRQTVEYDATAK-PLPYKQVTA----PNVERTGMGW-EVHAQSFTELLERVSKEYK 356 Query: 366 NPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDN 422 I+ITENG D +DD R Y + +F A + V + Y AWSL+DN Sbjct: 357 PKEIFITENGSAWDDEVVDGKVDDPNRVSYLERHLDAMFAA-KNKGVPISGYFAWSLIDN 415 Query: 423 FEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 FEW GY+ RFG+ +VD++ + R+P +SA Y K I+ + Sbjct: 416 FEWAYGYAKRFGIIYVDYQ--TQKRIPKSSAYYYQKRIKES 454 >5DT5-A nrPDB Length = 471 Score = 219 bits (557), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 144/466 (30%), Positives = 229/466 (49%), Gaps = 29/466 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 M F F + AT++YQ+EG D G+ P +WDTF G +VF+ GDVAC Y +E Sbjct: 24 MKFAPNFVFGTATSSYQIEGAHDEGGRTPSIWDTFCDTDG-KVFEKHNGDVACDHYHRFE 82 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ IKQLG+ YRFS++W R+ P + G N +G+ +Y + L + G+ P VTLYH Sbjct: 83 EDIQHIKQLGVDTYRFSIAWPRIFP--SKGQFNPEGMAFYKTLATRLQEEGIKPAVTLYH 140 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLP ++GGW++ ++ F +A+ CF V WIT NE +SY LG Sbjct: 141 WDLPMWAHEEGGWVNRDSVDWFLDFARVCFEELDGIVDSWITHNEPWCAGFLSYHLGQHA 200 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG +A H+++ +H ++ F ++L+L + A +S++DQ Sbjct: 201 PGHTDMNE-AVRAVHHMLLSHGKAVEMLKGEFNSATPIGITLNLAPKY---AKTDSINDQ 256 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 A A + F PIF G YP + + + + + + I Sbjct: 257 IAMNNADGYANRWFLDPIF-KGQYPVDMMNLFSKYVHTYDFIHAG-------DLATISTP 308 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DFF + +Y+ L+++ + +DA + D + W + P L++ + Sbjct: 309 CDFFGINFYSRNLVEFSAASD---FLHKDA----YSDYDKTGMGWD-IAPSEFKDLIRRL 360 Query: 361 KDTYNNPVIYITENGFPQSD---PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 + Y + IYITENG D + D R +Y Q Q + + + +N+ Y W Sbjct: 361 RAEYTDLPIYITENGAAFDDQLVDGKIHDQNRIDYVAQHLQAV-SDLNDEGMNIAGYYLW 419 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 SLLDNFEW+ GY RFG+ +VDF+ + R+ SA YA +I+ + Sbjct: 420 SLLDNFEWSFGYDKRFGIIYVDFD--TQERIWKDSAHWYANVIQTH 463 >5WKA-A nrPDB Length = 473 Score = 219 bits (557), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 164/504 (32%), Positives = 223/504 (44%), Gaps = 73/504 (14%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W +TAAYQ+EG DG+ P +WDTF+ G +V TGDVAC Y WEED Sbjct: 2 FPDGFVWGTSTAAYQIEGAVAEDGRTPSIWDTFSRTKG-KVVNGDTGDVACDHYHRWEED 60 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 L + +LG+ YRFS++W R+ PD TG NQKG+D+Y ++ID L + P+ T+YH+D Sbjct: 61 LDLLAELGVQAYRFSVAWPRIHPD-VTGPANQKGLDFYQRLIDGLRDRNIIPLPTMYHWD 119 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ LED+GGW+ F YA D + +W T NE + + Y G PG Sbjct: 120 LPQALEDEGGWIVRDTALRFADYAATVLEKL-DGIDKWTTFNEPWTSAWLGYGYGHHAPG 178 Query: 183 IPHFGTG-------------GYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 G G QAA I+ H + L+L L Sbjct: 179 RTDIGAAAAATHHLLLAHGLGVQAAR-AIRPHVE----------------IGLTLNLGVL 221 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 P D EA RA ++ P+F G+YP A M + + Sbjct: 222 RPGTTED-QDVEATWRADGNQNRIWLDPLF-KGEYP-------ADMIEHYSRWTPGFHTV 272 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVV 349 + ++I DF V +Y + G + A P P + + + Sbjct: 273 QNGDLEIISSPIDFLGVNFYGPGTVM----NVGREDAARAAGFNVGPRPESDEDNHLRCI 328 Query: 350 ------------PWGV-----CKLLKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQ 388 W V +LL IK+ Y + +YITENG D + D + Sbjct: 329 GVETPGRPKTAMGWEVDATALRELLVRIKNEYTDIPLYITENGAAYHDYVNASGDVKDPE 388 Query: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448 R Y + AI D VNLQ Y WSLLDNFEW GYS RFG+ +D+ D R R+ Sbjct: 389 RITYLNDHLEACLGAID-DGVNLQGYFIWSLLDNFEWGFGYSRRFGIVWIDY-DTGR-RI 445 Query: 449 PYTSAKEYAKIIRNNG---LEAHL 469 P S + Y ++ NG L+ HL Sbjct: 446 PKASYRWYQGVVATNGLPDLDGHL 469 >3ZJK-A nrPDB Length = 431 Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 144/458 (31%), Positives = 224/458 (48%), Gaps = 43/458 (9%) Query: 7 FGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCI 66 F W AT+AYQ+EG DG+GP +WD F + G + TG+ AC Y +EED+ + Sbjct: 8 FLWGVATSAYQIEGATQEDGRGPSIWDAFAQRPGA-IRDGSTGEPACDHYRRYEEDIALM 66 Query: 67 KQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQT 126 + LG+ YRFS++W R+LP+G G IN KG+ +Y++++D LL +G+TP +TLYH+DLP Sbjct: 67 QSLGVRAYRFSVAWPRILPEGR-GRINPKGLAFYDRLVDRLLASGITPFLTLYHWDLPLA 125 Query: 127 LEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHF 186 LE++GGW S +F +YA+ DRV + T+NE + + + G PG+ + Sbjct: 126 LEERGGWRSRETAFAFAEYAEAVARALADRVPFFATLNEPWCSAFLGHWTGEHAPGLRNL 185 Query: 187 GTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRA 246 +AAH+L+ H + + + ++ +++ + P D EA A Sbjct: 186 -EAALRAAHHLLLGHGLAVEALRAAGARRVGIVLNFA----------PAYGEDPEAVDVA 234 Query: 247 ITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAV 306 +H F PI G YPE + P + +++ DF V Sbjct: 235 DRYHNRFFLDPILGKG-YPE------SPFRDPPPVP------ILSRDLELVARPLDFLGV 281 Query: 307 QYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNN 366 YY + G L + + P V P G+ LLK + Sbjct: 282 NYYAPVRVA---PGTGTL------PVRYLPPEGPATAMGWEVYPEGLHHLLKRLGREVPW 332 Query: 367 PVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDN 422 P +Y+TENG D A ++D +R Y + +A + + V+L+ Y WSL+DN Sbjct: 333 P-LYVTENGAAYPDLWTGEAVVEDPERVAYLEAHVEAALRARE-EGVDLRGYFVWSLMDN 390 Query: 423 FEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII 460 FEW GY+ R GL++VDF P++ R+P SA Y + I Sbjct: 391 FEWAFGYTRRSGLYYVDF--PSQRRIPKRSALWYRERI 426 >1PBG-A nrPDB Length = 468 Score = 208 bits (529), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 152/485 (31%), Positives = 226/485 (46%), Gaps = 40/485 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 P F + ATAAYQ EG DGKGP WD + T + A Y + Sbjct: 4 TLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDN-----YWYTAEPASDFYHKYPV 58 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL+ ++ G+ R S++WSR+ P G G +N+KG+++Y+K+ + K V P VTL+HF Sbjct: 59 DLELAEEYGVNGIRISIAWSRIFPTGY-GEVNEKGVEFYHKLFAECHKRHVEPFVTLHHF 117 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 D P+ L G +L+ IE F YA FCF F + V W T NE + Y +G FPP Sbjct: 118 DTPEALHSNGDFLNRENIEHFIDYAAFCFEEFPE-VNYWTTFNEIGPIGDGQYLVGKFPP 176 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 GI + +Q+ HN++ +HAR+ Y K KG + + P DP + +D Sbjct: 177 GIKYDLAKVFQSHHNMMVSHARAVKLYKD---KGYKGEIGVVHALPTKYPYDPENPADVR 233 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIAS-MSQKQGYPSSRLPEFTEEEKKMIKGT 300 AA+ H ++ G Y + + +++ G R +F + K Sbjct: 234 AAELEDIIHNKFILDATYL-GHYSDKTMEGVNHILAENGGELDLRDEDF--QALDAAKDL 290 Query: 301 ADFFAVQYYT----------TRLIKYQENKKGE-----LGILQDAEIEFFPDPSWKNVDW 345 DF + YY T +I + +KG G+ + ++ P W DW Sbjct: 291 NDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRVAPDYVPRTDW---DW 347 Query: 346 IYVVPWGVCKLLKYIKDTY-NNPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELF 401 I + P G+ + +K+ Y N IYITENG D + D R +Y +Q + L Sbjct: 348 I-IYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKQHLEVLS 406 Query: 402 KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 461 AI D N++ Y WSL+D F W+ GY R+GLF+VDF+ + R P SA Y K+ Sbjct: 407 DAIA-DGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFD--TQERYPKKSAHWYKKLAE 463 Query: 462 NNGLE 466 +E Sbjct: 464 TQVIE 468 >4F66-A nrPDB Length = 480 Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 138/489 (28%), Positives = 221/489 (45%), Gaps = 45/489 (9%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY------ 56 P F W A AA+Q+EGGW GKG V D T G V + T V G Y Sbjct: 7 LPENFLWGGAVAAHQLEGGWQEGGKGISVADVMT-AGRHGVAREITAGVLEGKYYPNHEA 65 Query: 57 ----TLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112 ++ED+K ++G +R S++W+R+ P G N+ G+ +Y+ + D+ LK G+ Sbjct: 66 IDFYHHYKEDVKLFAEMGFKCFRTSIAWTRIFPKGDEAEPNEAGLQFYDDLFDECLKYGI 125 Query: 113 TPIVTLYHFDLPQTL-EDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSV 171 P+VTL HF+LP L + GG+ + +I+ F +A+ CF + D+VK W+T NE N + Sbjct: 126 EPVVTLSHFELPYHLVTEYGGFTNRKVIDFFVHFAEVCFRRYKDKVKYWMTFNEINNQAN 185 Query: 172 MSYDLGMFPPGIPHFGTGG------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLF 225 D F + G YQAAH + A AR+ ++ G + +++ Sbjct: 186 YQEDFAPFTNSGIVYKEGDDREAIMYQAAHYELVASARAVKIGHAINPNLNIGCM-VAMC 244 Query: 226 AVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSR 285 ++ +P + + A + + D + + G YPE + + K Sbjct: 245 PIYPATCNPKDILMAQKAMQKRYYFAD-----VHVHGFYPEHIFKYWERKAIK------- 292 Query: 286 LPEFTEEEKK-MIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD 344 +FTE +KK + +GT D+ YY + +I L+ ++ +P K D Sbjct: 293 -VDFTERDKKDLFEGTVDYIGFSYYMSFVIDAHRENNPYYDYLETEDL--VKNPYVKASD 349 Query: 345 WIYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLD----DTQRWEYFRQTFQE 399 W + + P G+ L + D Y+ P ++I ENGF D D D R +Y +E Sbjct: 350 WDWQIDPQGLRYALNWFTDMYHLP-LFIVENGFGAIDQVEADGMVHDDYRIDYLGAHIKE 408 Query: 400 LFKAIQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPAR---PRVPYTSAKE 455 + KA+ D V L Y W +D G R+G +VD +D + R P S Sbjct: 409 MIKAVDEDGVELMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDEGKGTLKRSPKLSFNW 468 Query: 456 YAKIIRNNG 464 Y ++I +NG Sbjct: 469 YKEVIASNG 477 >2XHY-A nrPDB Length = 479 Score = 169 bits (429), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 130/491 (26%), Positives = 220/491 (44%), Gaps = 47/491 (9%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY---- 56 + P F W A AA+QVEGGW+ GKGP + D T G V + T +V G Y Sbjct: 6 LTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLT-GGAHGVPREITKEVLPGKYYPNH 64 Query: 57 ------TLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110 ++ED+K ++G +R S++W+R+ P G N++G+ +Y+ + D+LLK Sbjct: 65 EAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDELLKY 124 Query: 111 GVTPIVTLYHFDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVL 169 + P++TL HF++P L Q G W + +++ F ++A+ F + +VK W+T NE N Sbjct: 125 NIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNEINNQ 184 Query: 170 SVMSYDL-GMFPPGIPHFGTGG-----YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223 L G G+ + YQ H+ A A + + + + + G + L+ Sbjct: 185 RNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFVASALAVKAARRINPEMKVGCM-LA 243 Query: 224 LFAVWLEPADPNSVS-DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYP 282 + ++ +P+ V QE+ + F + + G YP V ++ Sbjct: 244 MVPLYPYSCNPDDVMFAQESMRERYVF------TDVQLRGYYPSYVLNEWERRGFNIKME 297 Query: 283 SSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKN 342 L E GT D+ YY T +K + + + + P+P K Sbjct: 298 DGDLDVLRE-------GTCDYLGFSYYMTNAVKAEGGTGDAISGFEGS----VPNPYVKA 346 Query: 343 VDWIYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTF 397 DW + + P G+ L + + Y P ++I ENGF D ++D R +Y R Sbjct: 347 SDWGWQIDPVGLRYALCELYERYQRP-LFIVENGFGAYDKVEEDGSINDDYRIDYLRAHI 405 Query: 398 QELFKAIQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPARPRVPYTSAKE- 455 +E+ KA+ D V+L Y W +D + G YS R+G +V+ D + + K Sbjct: 406 EEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSF 465 Query: 456 --YAKIIRNNG 464 Y ++I +NG Sbjct: 466 NWYKEVIASNG 476 >4B3K-A nrPDB Length = 479 Score = 165 bits (417), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 136/482 (28%), Positives = 223/482 (46%), Gaps = 38/482 (7%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 +AFP F W AT+ Q EG + + ++D + + + + D A +Y E Sbjct: 1 LAFPKEFWWGGATSGPQSEGRFAKQHRN--LFDYWYEEEPDLFYDYVGPDTASDAYHQIE 58 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 DL + LG YR S+ W+RL+ D IN G+ YYN++ID L NG+ P++ L+H Sbjct: 59 SDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRVIDACLANGIRPVINLHH 118 Query: 121 FDLPQTL-EDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 FDLP L + GGW S+ +++ F +++ CF FGDRVK W NE V+ SY + Sbjct: 119 FDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDWFVHNEPMVVVEGSYLMQFH 178 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVS- 238 P I G Q A+NL A A+ +Y + G + L L PA P S S Sbjct: 179 YPAIVD-GKKAVQVAYNLALATAKVIQAYRRGPAELSDGRIGTILN---LTPAYPASQSE 234 Query: 239 -DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMI 297 D AA A ++ DLF + + G +PE ++ ++ +K G P EE + Sbjct: 235 ADMAAAHFAELWNNDLFMEAA-VHGKFPE----ELVAVLKKDGVLWQSTP---EELALIA 286 Query: 298 KGTADFFAVQYYTTRLIKYQENKKGELGILQDA-EIEFFPDP-----SWKNVDWIY-VVP 350 + D+ + +Y + +K + + ++ + E++ DP NVD + + P Sbjct: 287 ENRVDYLGLNFYHPKRVKAPD----AIPVISPSWSPEWYYDPYLMPGRRMNVDKGWEIYP 342 Query: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQS-------DPAPLDDTQRWEYFRQTFQELFKA 403 V + ++D Y+N +++ENG S + + D R ++ ++ L K Sbjct: 343 EAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQFLKEHLTYLHKG 402 Query: 404 IQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 I+ N Y W+ +D + W Y +R+GL + + R P SA + K+ +N Sbjct: 403 IEAGS-NCFGYHVWTPIDGWSWLNAYKNRYGLVENNIH--TQVRRPKASAYWFKKVATHN 459 Query: 464 GL 465 L Sbjct: 460 RL 461 >5NAV-A nrPDB Length = 477 Score = 164 bits (416), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 138/478 (28%), Positives = 218/478 (45%), Gaps = 31/478 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP GF W AAT+ Q EG + + V+D + E+ D A Y ++ Sbjct: 18 VEFPEGFVWGAATSGPQTEGNFHKQHQN--VFDYWFATEPEQFDAGVGPDTASNFYNDYD 75 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 DL + Q G+ R S+ W+RL+ D T +N G+ +YN +ID +L + +TP + L+H Sbjct: 76 HDLALMAQAGVQGLRTSIQWTRLIDDFETASLNADGVAFYNHVIDSMLAHHITPYINLHH 135 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 FDLP L D+ GW S+ ++E F K+A+ CF FGDRV W T NE V+ Y G Sbjct: 136 FDLPVALYDKYHGWESKHVVELFVKFAEQCFKLFGDRVDHWYTFNEPKVVVDGQYLYGWH 195 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSL-FRKKQKGMVSLSLFAVWLEPADPNSVS 238 P + + G Q A+N+ A A++ + L R +Q+ + L+L + DP + Sbjct: 196 YPQVIN-GPKAVQVAYNMNLASAKTVARFHELSVRPEQQIGIILNLTPAYAASDDP---A 251 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298 D AA+ A + +LF P + G +PE + ++ L + T E +I Sbjct: 252 DLAAAEFAELWSNNLFLDPAVL-GHFPEKLVERLTM--------DGVLWDATPTELAIIA 302 Query: 299 GT-ADFFAVQYYTT-RLIKYQENKKGELGILQDAEIEFFPDPS-WKNVDWIY-VVPWGVC 354 D V YY R+ + + K + D + + P NVD + + P + Sbjct: 303 ANPVDSLGVNYYHPFRVQRPDISPKSLQPWMPDIYFKEYDMPGRMMNVDRGWEIYPQAMT 362 Query: 355 KLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ-------RWEYFRQTFQELFKAIQLD 407 + + I+ Y N I+ENG + D Q R ++ ++ L K I Sbjct: 363 DIARNIQKNYGNIPWMISENGMGVAGEERFLDKQGVVQDDYRIDFMKEHLTALAKGIAAG 422 Query: 408 KVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 N Q Y WS +D + WN Y +R+GL D + + SAK +A++ NG Sbjct: 423 S-NCQGYFVWSGIDCWSWNHAYHNRYGLIRNDIH--TQTKTLKKSAKWFAELGERNGF 477 >1VFF-A nrPDB Length = 423 Score = 160 bits (404), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 143/470 (30%), Positives = 225/470 (47%), Gaps = 61/470 (12%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F + AT+++Q+EG + + W + Q G+ +++ AC + L+ Sbjct: 3 LKFPEMFLFGTATSSHQIEG----NNRWNDWW--YYEQIGKLPYRSGK---ACNHWELYR 53 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 +D++ + LG YRFS+ WSRL P+ N+ Y +IID LL G+TP+VTL+H Sbjct: 54 DDIQLMTSLGYNAYRFSIEWSRLFPEENK--FNEDAFMKYREIIDLLLTRGITPLVTLHH 111 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 F P +GG+L E ++ ++KY + + ++VK T NE V +M Y +P Sbjct: 112 FTSPLWFMKKGGFLREENLKHWEKYIE-KVAELLEKVKLVATFNEPMVYVMMGYLTAYWP 170 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 P I ++ A NL+KAHA +Y+ L K + G+V + L +D D+ Sbjct: 171 PFIRS-PFKAFKVAANLLKAHAI---AYELLHGKFKVGIV--KNIPIILPASDKE--RDR 222 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 +AA++A D F+D I S + + + R+P+ Sbjct: 223 KAAEKA-----DNLFNWHFLDA---------IWSGKYRGVFKTYRIPQ----------SD 258 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEI-EFFPDPSWKNVDWIYVVPWGVCKLLKY 359 ADF V YYT +++ N ++ A+I E W V P G+ LK Sbjct: 259 ADFIGVNYYTASEVRHTWNPLKFFFEVKLADISERKTQMGWS------VYPKGIYMALK- 311 Query: 360 IKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSL 419 Y P +YITENG A LDD R E+ Q Q + KAI+ D ++++ Y WS Sbjct: 312 KASRYGRP-LYITENGI-----ATLDDEWRVEFIIQHLQYVHKAIE-DGLDVRGYFYWSF 364 Query: 420 LDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 +DN+EW +G+ RFGL VD++ R P SA Y +I R+ ++ L Sbjct: 365 MDNYEWKEGFGPRFGLVEVDYQ--TFERRPRKSAYVYGEIARSKEIKDEL 412 >4GZE-A nrPDB Length = 481 Score = 151 bits (382), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 139/490 (28%), Positives = 222/490 (45%), Gaps = 45/490 (9%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVA--------- 52 AFP GF W A AA+Q+EGG+ GKG D T ER + G VA Sbjct: 10 AFPEGFLWGGAVAAHQLEGGYKEGGKGLSTADIMTLGTNERPREITDGVVAGKYYPNHQA 69 Query: 53 CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112 Y + ED++ ++G +R S++W+R+ P+G N+ G+ +Y+ + D+ LKNG+ Sbjct: 70 IDFYHRYPEDIELFAEMGFKCFRTSIAWTRIFPNGDESEPNEAGLQFYDDLFDECLKNGI 129 Query: 113 TPIVTLYHFDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSV 171 P+VTL HF++P L Q GGW + +I+ + +A+ CF + D+V W+T NE N + Sbjct: 130 QPVVTLAHFEMPYHLVKQYGGWRNRKLIQFYLNFAKVCFERYRDKVTYWMTFNEINNQTN 189 Query: 172 MSYDLGMFP-PGIPHFGTGG-----YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLF 225 D M GI H YQAAH + A A + + Q G + +++ Sbjct: 190 FESDGAMLTDSGIIHQPGENRERWMYQAAHYELVASAAAVQLGHQINPDFQIGCM-IAMC 248 Query: 226 AVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSR 285 ++ A P +D A+RA+ + + +G YP+ ++++ S Sbjct: 249 PIYPLTAAP---ADVLFAQRAM--QTRFYFADVHCNGTYPQWLRNRFES-------EHFN 296 Query: 286 LPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDW 345 L E+ K + GT D+ YY + +K G+L + E + +P K DW Sbjct: 297 LDITAEDLKILQAGTVDYIGFSYYMSFTVK----DTGKLAY--NEEHDLVKNPYVKASDW 350 Query: 346 IYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLD----DTQRWEYFRQTFQEL 400 + V P G+ + + D Y+ P ++I ENG D D D R +Y +++ Sbjct: 351 GWQVDPVGLRYAMNWFTDRYHLP-LFIVENGLGAIDKKTADNQIHDDYRIDYLTDHLRQI 409 Query: 401 FKAIQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPAR---PRVPYTSAKEY 456 A+ D V+L Y W +D + G S R+G +VD D R S + Sbjct: 410 KLAVLEDGVDLIGYTPWGCIDLVAASTGQMSKRYGFIYVDENDDGSGSLKRYKKDSFTWF 469 Query: 457 AKIIRNNGLE 466 +I NG E Sbjct: 470 QHVIATNGAE 479 >4IPN-B nrPDB Length = 487 Score = 150 bits (380), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 131/485 (27%), Positives = 216/485 (44%), Gaps = 45/485 (9%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGD----VACGSYTL 58 FP F W A AA QVEG ++ DGKG V D G +N T D + Y Sbjct: 20 FPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEATENPTEDNLKLIGIDFYHK 79 Query: 59 WEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTL 118 ++ED+ ++G +R S++WSR+ P G N+ G+ YY+++ D+L +G+ P+VTL Sbjct: 80 YKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGLKYYDELFDELHAHGIEPLVTL 139 Query: 119 YHFDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEAN-VLSVMSYDL 176 H++ P L + GW+ +I ++K+A+ + D+VK W+T NE N VL + Sbjct: 140 SHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYKDKVKYWLTFNEVNSVLELPFTSG 199 Query: 177 GMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNS 236 G+ P YQA H+ + A + + + + G + L++ PA P + Sbjct: 200 GIDIPKENLSKQELYQAIHHELVASSLVTKIAREINSEFKVGCMVLAM------PAYPMT 253 Query: 237 VSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296 + ++ +L+ + + G YP K EF E+ ++ Sbjct: 254 PNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKENDIN--------IEFAAEDAEL 305 Query: 297 IKG-TADFFAVQYY---TTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVV-PW 351 +K T DF + YY T + Q N GE I I +P ++ +W + + P Sbjct: 306 LKNYTVDFLSFSYYMSVTQSALPTQYN-SGEGNI-----IGGLVNPYLESSEWGWQIDPI 359 Query: 352 GVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLD--------DTQRWEYFRQTFQELFKA 403 G+ +L D Y P ++I ENG D D D R +Y ++ ++ +A Sbjct: 360 GLRIILNRYYDRYQIP-LFIVENGLGAKDQLIKDELNNLTVQDDYRIQYMKEHLLQVAEA 418 Query: 404 IQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPAR---PRVPYTSAKEYAKI 459 +Q D V + Y +W +D + S R+GL +VD D R S Y ++ Sbjct: 419 LQ-DGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRYKKMSFTWYKEV 477 Query: 460 IRNNG 464 I +NG Sbjct: 478 IESNG 482 >4R27-A nrPDB Length = 434 Score = 124 bits (312), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 121/453 (26%), Positives = 187/453 (41%), Gaps = 57/453 (12%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W ATA +QVEG + VW F +F +GD A Y + ED Sbjct: 7 FPQDFLWGVATAGHQVEG----NNVNSDVW--FLEHLPGTIFAEPSGD-AVDHYHRYRED 59 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + I LG T YRFS+ W+R+ P+ G + +D+Y ++++ ++G+TP+VT +HF Sbjct: 60 IALIAGLGFTSYRFSVEWARIEPE--EGHFSVAALDHYKRVLEACREHGLTPVVTFHHFA 117 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 P L GGW E E F +Y + GD + T+NE N+ P Sbjct: 118 SPLWLLRSGGWEGERTPELFARYCGRVMAHLGDLIGVACTLNEPNL-----------PWL 166 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + FG GG +A N + W + + + E ++ +A Sbjct: 167 LESFGIGG-EAPEN--RGKVPMWAAAAQRLGVDASTVAPFQFCST--EAGFNVKLAAHKA 221 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A AI H +P G + S I S+ + + + E + +G D Sbjct: 222 ATEAIKAH-----RPDLRVGW--TLANSDIQSVPGGEEIAAQVRRDVNERFLEASRGD-D 273 Query: 303 FFAVQYYTTRLIKYQENKKGELGI-LQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIK 361 F +Q Y + + G+ + E +P + ++ W V + Sbjct: 274 FVGIQTYGRTVYGPDGHAPAPEGVAVNQMGEEIYP----QALEATIREAWRVAGI----- 324 Query: 362 DTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLD 421 PV+ +TENG A DDTQR Y R + + D ++++ Y AW+ D Sbjct: 325 -----PVM-VTENGL-----ATEDDTQRVAYLRTAVDGVASCLA-DGIDVRGYIAWTAFD 372 Query: 422 NFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 NFEW GY +FGL VD + R P SA+ Sbjct: 373 NFEWIFGYGPKFGLIAVDRS--TQERTPKESAR 403 >4HA4-A nrPDB Length = 489 Score = 119 bits (297), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 125/487 (25%), Positives = 196/487 (40%), Gaps = 90/487 (18%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F + + A +Q E G W + H +GD W Sbjct: 2 VTFPKDFLFGWSQAGFQSEMGTPGSEDPNSDWYAWVHDRENIAAGLVSGDFPENGPGYWG 61 Query: 61 EDLK---CIKQLGLTHYRFSLSWSRLLPDGT---------------------------TG 90 K + +GLT R + WSR+ P T Sbjct: 62 NYRKFHDAAQAMGLTAARIGVEWSRIFPRPTFDVKVDAEVKGDDVLSVYVSEGALEQLDK 121 Query: 91 FINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED-----------QGGWLSEAII 139 N+ I++Y ++ DL G+T I+ LYH+ LP L D GWL + Sbjct: 122 MANRDAINHYREMFSDLRSRGITFILNLYHWPLPLWLHDPIAIRRGNLSAPSGWLDVRTV 181 Query: 140 ESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDL--GMFPPGIPHFGTGGYQAAHNL 197 F K++ + D V + T+NE NV+ + Y FPPG G +A NL Sbjct: 182 IEFAKFSAYVAWKLDDLVYMYSTMNEPNVVWGLGYAAVKSGFPPGYLCLECAG-RAMKNL 240 Query: 198 IKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKP 257 ++AHAR++ + ++ +K + + S F P + +D+EAA+RA + Sbjct: 241 VQAHARAYDAVKAITKKPVGVIYANSDFT-------PLTDADREAAERA-----KFDNRW 288 Query: 258 IFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQ 317 F D VV+ Q+ ++ +KG D+ V YYT ++++ + Sbjct: 289 AFFDA----VVRGQLGGSTRDD-----------------LKGRLDWIGVNYYTRQVVRAR 327 Query: 318 ----ENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITE 373 E G + + P + W + P G+ +LK D Y+ P++ +TE Sbjct: 328 GSGYEIVPGYGHGCEPNGVSPAGRPC-SDFGWEF-YPEGLYNVLKEYWDRYHLPLL-VTE 384 Query: 374 NGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRF 433 NG A D QR Y ++ +A+Q D VN+ Y WSL DN+EW G+S RF Sbjct: 385 NGI-----ADEGDYQRPYYLVSHVYQVHRALQ-DGVNVIGYLHWSLADNYEWASGFSKRF 438 Query: 434 GLFHVDF 440 GL VD+ Sbjct: 439 GLLMVDY 445 >1QVB-A nrPDB Length = 481 Score = 111 bits (277), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 131/519 (25%), Positives = 209/519 (40%), Gaps = 95/519 (18%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV---ACGSYT 57 M FP F +++ +Q E G W + H +GD G + Sbjct: 1 MKFPKDFMIGYSSSPFQFEAGIPGSEDPNSDWWVWVHDPENTAAGLVSGDFPENGPGYWN 60 Query: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGT-----------TGFI-------------- 92 L + D ++LG+ R + WSR+ P T G I Sbjct: 61 LNQNDHDLAEKLGVNTIRVGVEWSRIFPKPTFNVKVPVERDENGSIVHVDVDDKAVERLD 120 Query: 93 ---NQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED------------QGGWLSEA 137 N++ +++Y ++ D ++ G I+ LYH+ LP L + GWL+E Sbjct: 121 ELANKEAVNHYVEMYKDWVERGRKLILNLYHWPLPLWLHNPIMVRRMGPDRAPSGWLNEE 180 Query: 138 IIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDL--GMFPPGIPHFGTGGYQAAH 195 + F KYA + G+ W T+NE NV+ Y G FPPG +A Sbjct: 181 SVVEFAKYAAYIAWKMGELPVMWSTMNEPNVVYEQGYMFVKGGFPPGYLSLEAAD-KARR 239 Query: 196 NLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPAD-PNSVSDQEAAKRAITFHLDLF 254 N+I+AHAR +YD++ R +K + + F W E + P V D+ + + F D+ Sbjct: 240 NMIQAHAR---AYDNIKRFSKKPVGLIYAFQ-WFELLEGPAEVFDKFKSSKLYYF-TDIV 294 Query: 255 AKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLI 314 +K S I ++ E ++ + D+ V YY+ + Sbjct: 295 SK------------GSSIINV----------------EYRRDLANRLDWLGVNYYSRLVY 326 Query: 315 KYQENK----KGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIY 370 K ++K G + I +P + W V P G+ LLK + + Y +I Sbjct: 327 KIVDDKPIILHGYGFLCTPGGISPAENPC-SDFGW-EVYPEGLYLLLKELYNRYGVDLI- 383 Query: 371 ITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYS 430 +TENG S D R Y ++KA + + ++ Y WSL DN+EW QG+ Sbjct: 384 VTENGVSDS-----RDALRPAYLVSHVYSVWKAAN-EGIPVKGYLHWSLTDNYEWAQGFR 437 Query: 431 SRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 +FGL VDF+ R P SA + +I +NG+ L Sbjct: 438 QKFGLVMVDFKTKKRYLRP--SALVFREIATHNGIPDEL 474 >3WDP-P nrPDB Length = 473 Score = 108 bits (271), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 125/493 (25%), Positives = 195/493 (39%), Gaps = 107/493 (21%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV---ACGSYTLW 59 FP F + + + +Q E G + W + H +GD+ + L+ Sbjct: 4 FPKNFMFGYSWSGFQFEMGLPG-SEVESDWWVWVHDKENIASGLVSGDLPENGPAYWHLY 62 Query: 60 EEDLKCIKQLGLTHYRFSLSWSRLLPDGT----------------------------TGF 91 ++D ++LG+ R + W+R+ P T Sbjct: 63 KQDHDIAEKLGMDCIRGGIEWARIFPKPTFDVKVDVEKDEEGNIISVDVPESTIKELEKI 122 Query: 92 INQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQ------------GGWLSEAII 139 N + +++Y KI D + G T I+ LYH+ LP + D GWL E + Sbjct: 123 ANMEALEHYRKIYSDWKERGKTFILNLYHWPLPLWIHDPIAVRKLGPDAAPAGWLDEKTV 182 Query: 140 ESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY-DLGM-FPPGIPHFGTGGYQAAHNL 197 F K+A F D V W T+NE NV+ Y +L FPPG F +A NL Sbjct: 183 VEFVKFAAFVAYHLDDLVDMWSTMNEPNVVYNQGYINLASGFPPGFLSF-EAAEKAKFNL 241 Query: 198 IKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKP 257 I+AH +YD++ +K + + FA W +P + E ++ Sbjct: 242 IQAHIG---AYDAIKEYSEKSVGVIYAFA-WHDPLAEEYKDEVEEIRKK----------- 286 Query: 258 IFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQ 317 D ++ ++ S KG D+ V YY +RL+ Sbjct: 287 ---DYEFVTILHS---------------------------KGKLDWIGVNYY-SRLV--Y 313 Query: 318 ENKKGELGILQD----AEIEFFPDPSWKNVDWIY-VVPWGVCKLLKYIKDTYNNPVIYIT 372 K G L L +E F D+ + + P G+ LLKY+ + Y P+I IT Sbjct: 314 GAKDGHLVPLPGYGFMSERGGFAKSGRPASDFGWEMYPEGLENLLKYLNNAYELPMI-IT 372 Query: 373 ENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSR 432 ENG A D R Y + ++ A++ + +++ Y WSL DN+EW QG+ R Sbjct: 373 ENGM-----ADAADRYRPHYLVSHLKAVYNAMK-EGADVRGYLHWSLTDNYEWAQGFRMR 426 Query: 433 FGLFHVDFEDPAR 445 FGL +VDFE R Sbjct: 427 FGLVYVDFETKKR 439 >1GOW-A nrPDB Length = 489 Score = 98.2 bits (243), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 117/488 (23%), Positives = 198/488 (40%), Gaps = 91/488 (18%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVA------CGS 55 +FP F + + A +Q E G W + H +GD+ G+ Sbjct: 3 SFPNSFRFGWSQAGFQSEMGTPGSEDPNTDWYKWVHDPENMAAGLVSGDLPENGPGYWGN 62 Query: 56 YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPD--------------------------GTT 89 Y + ++ +++GL R + WSR P+ Sbjct: 63 YKTFHDN---AQKMGLKIARLNSEWSRQFPNPLPRPQNFDESKQDVTEVEINENELKRLD 119 Query: 90 GFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQ-----------GGWLSEAI 138 + N+ +++Y +I DL G+ I +YH+ LP L D GWLS Sbjct: 120 EYANKDALNHYREIFKDLKSRGLYFIQNMYHWPLPLWLHDPIRVRRGDFTGPSGWLSTRT 179 Query: 139 IESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGM--FPPGIPHFGTGGYQAAHN 196 + F +++ + F D V ++ T+NE NV+ + Y FPPG F +A +N Sbjct: 180 VYEFARFSAYTAWKFDDLVDEYSTMNEPNVVGGLGYVGVKSGFPPGYLSFEL-SRRAMYN 238 Query: 197 LIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAK 256 +I+AHAR++ S+ +K + + S F P + D EA + A + F Sbjct: 239 IIQAHARAYDGIKSVSKKPVGIIYANSSF-------QPLTDKDMEAVEMAENDNRWWF-- 289 Query: 257 PIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316 + +++ +I ++K + +KG D+ V YYT ++K Sbjct: 290 -------FDAIIRGEITRGNEKI-------------VRDDLKGRLDWIGVNYYTRTVVKR 329 Query: 317 QENKKGELG----ILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYIT 372 E LG + + P+ + W + P G+ +L + Y + +Y+T Sbjct: 330 TEKGYVSLGGYGHGCERNSVSLAGLPT-SDFGWEF-FPEGLYDVLTKYWNRY-HLYMYVT 386 Query: 373 ENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSR 432 ENG +D A D QR Y ++ +AI +++ Y WSL DN+EW G+S R Sbjct: 387 ENGI--ADDA---DYQRPYYLVSHVYQVHRAIN-SGADVRGYLHWSLADNYEWASGFSMR 440 Query: 433 FGLFHVDF 440 FGL VD+ Sbjct: 441 FGLLKVDY 448 >3NCO-A nrPDB Length = 320 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Query: 54 GSYTLWEED--LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNG 111 GS+ ++ ED K IK+ G R + WS + + I++ +D ++D LKN Sbjct: 36 GSWGVYIEDEYFKIIKERGFDSVRIPIRWSAHISEKYPYEIDKFFLDRVKHVVDVALKND 95 Query: 112 VTPIVTLYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRV 157 + I+ +HF+ D+ G ++E + + AQ F + D++ Sbjct: 96 LVVIINCHHFEELYQAPDKYG---PVLVEIWKQVAQ-AFKDYPDKL 137 >5H4R-A nrPDB Length = 396 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 17/72 (23%), Positives = 38/72 (52%), Gaps = 2/72 (2%) Query: 53 CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112 CG T ++ + +K+ G R +SW + G+ I+++ +D +++D +KN + Sbjct: 77 CGVKTT-KQMIDTVKKAGFNTIRIPVSWHNHVT-GSNFTISKRWLDRVQQVVDYAMKNKM 134 Query: 113 TPIVTLYHFDLP 124 I+ ++H +P Sbjct: 135 YVIINIHHDIMP 146 >5GOQ-A nrPDB Length = 461 Score = 31.2 bits (69), Expect = 0.90, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 42 RVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGI 97 R ++ TGD+ ++ +K I L L H RFS+ + L+PDG + G+ Sbjct: 140 RAYEKATGDLTLAREPKFQAGIKLILDLCLAH-RFSMYPTMLVPDGAFMIDRRMGV 194 >3AZS-A nrPDB Length = 317 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 33/67 (49%), Gaps = 8/67 (11%) Query: 60 EEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL----LKNGVTPI 115 +E IK+ G +H R + WS F K +D + K +D++ LK G+ + Sbjct: 36 DEFFDIIKEAGFSHVRIPIRWS----THAYAFPPYKIMDRFFKRVDEVINGALKRGLAVV 91 Query: 116 VTLYHFD 122 + ++H++ Sbjct: 92 INIHHYE 98 >3QR3-A nrPDB Length = 340 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 12/56 (21%), Positives = 29/56 (51%) Query: 66 IKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + + G+T +R + W L+ + G ++ I Y++++ L G IV ++++ Sbjct: 52 VNEDGMTIFRLPVGWQYLVNNNLGGNLDSTSISKYDQLVQGCLSLGAYCIVDIHNY 107 >3PDK-A nrPDB Length = 469 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 30/59 (50%) Query: 305 AVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDT 363 ++++ + K + ++ E+ L D E++ P P+ N+ + G K L+YIK T Sbjct: 129 GIKFFGSDGFKLTDEQEAEIEALLDKEVDELPRPTGTNLGQVSDYFEGGQKYLQYIKQT 187 >1Y1U-A nrPDB Length = 585 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 6/60 (10%) Query: 272 IASMSQKQGYPSSRLPEF------TEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELG 325 + +MSQK + R E TE E K ++ T ++F +QY + I+ Q + G+L Sbjct: 7 VDAMSQKHLQINQRFEELRLITQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLGQLN 66 >3AYR-A nrPDB Length = 376 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 45 KNQTGDVAC-GSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKI 103 K+QT C G+ E+ K + +R +WS + I++K + +++ Sbjct: 49 KDQTASETCWGNPKTTEDMFKVLIDNQFNVFRIPTTWSGHFGEAPDYKIDEKWLKRVHEV 108 Query: 104 IDDLLKNGVTPIVTLYH 120 +D KNG I+ L+H Sbjct: 109 VDYPYKNGAFVILNLHH 125 >1XRE-A nrPDB Length = 217 Score = 28.5 bits (62), Expect = 6.0, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 4/61 (6%) Query: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDG---TTGFINQKGIDYYNKIIDD 106 ++ C TL +E + ++ G HY SL W + P G G + K IDYY D+ Sbjct: 66 ELLCNLETLPKEIVTAVRNNGGGHYCHSLFWEVMSPRGGGEPNGDV-AKVIDYYFNTFDN 124 Query: 107 L 107 L Sbjct: 125 L 125 >1CEO-A nrPDB Length = 343 Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust. Identities = 12/61 (19%), Positives = 29/61 (47%) Query: 60 EEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 E+D++ I + G H R + + D G + G+ Y ++ ++ K + ++ ++ Sbjct: 31 EKDIETIAEAGFDHVRLPFDYPIIESDDNVGEYKEDGLSYIDRCLEWCKKYNLGLVLDMH 90 Query: 120 H 120 H Sbjct: 91 H 91 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3VKK-A nrPDB 695 0.0 4GXP-A nrPDB 644 0.0 5YJ7-A nrPDB 612 e-176 2CBU-A nrPDB 602 e-172 2DGA-A nrPDB 597 e-171 3AIW-A nrPDB 595 e-170 3WBE-A nrPDB 594 e-170 3WQ4-A nrPDB 593 e-170 3PTM-A nrPDB 591 e-169 5OGZ-A nrPDB 590 e-169 4PTW-A nrPDB 590 e-169 3VIK-A nrPDB 589 e-169 3AHX-A nrPDB 589 e-169 3ZJ8-A nrPDB 588 e-168 1QOX-A nrPDB 587 e-168 4MDP-A nrPDB 584 e-167 1V02-A nrPDB 583 e-167 1WCG-A nrPDB 582 e-167 5IDI-A nrPDB 582 e-167 4A3Y-A nrPDB 582 e-166 5BWF-A nrPDB 579 e-165 3AHY-A nrPDB 579 e-165 2RGL-A nrPDB 578 e-165 1BGG-A nrPDB 576 e-164 4HZ6-A nrPDB 575 e-164 5CG0-A nrPDB 573 e-164 5JBO-A nrPDB 573 e-164 2E40-A nrPDB 571 e-163 1CBG-A nrPDB 564 e-161 1E55-A nrPDB 559 e-160 5XGZ-A nrPDB 559 e-159 5AYI-A nrPDB 553 e-158 2Z1S-A nrPDB 545 e-155 4JIE-A nrPDB 545 e-155 3W53-A nrPDB 544 e-155 1GNX-A nrPDB 540 e-154 5GNX-A nrPDB 538 e-153 5DT5-A nrPDB 534 e-152 5NS7-A nrPDB 530 e-151 5YHS-A nrPDB 525 e-149 5VAQ-A nrPDB 522 e-148 4ZEN-A nrPDB 520 e-148 5WKA-A nrPDB 511 e-145 5WI9-A nrPDB 510 e-145 5W21-A nrPDB 507 e-144 3ZJK-A nrPDB 503 e-143 1W9D-M nrPDB 488 e-138 1PBG-A nrPDB 475 e-134 2XHY-A nrPDB 471 e-133 4F66-A nrPDB 467 e-132 5NAV-A nrPDB 452 e-127 4B3K-A nrPDB 448 e-126 4GZE-A nrPDB 448 e-126 4IPN-B nrPDB 446 e-126 1VFF-A nrPDB 404 e-113 4HA4-A nrPDB 399 e-111 1QVB-A nrPDB 378 e-105 3WDP-P nrPDB 369 e-102 1GOW-A nrPDB 362 e-100 4R27-A nrPDB 350 9e-97 Sequences not found previously or not previously below threshold: 3NCO-A nrPDB 42 4e-04 4IM4-A nrPDB 37 0.012 4UCF-A nrPDB 37 0.017 5H4R-A nrPDB 35 0.063 1CEO-A nrPDB 34 0.12 4EKJ-A nrPDB 34 0.18 3AZS-A nrPDB 33 0.31 4UOQ-A nrPDB 32 0.48 3CMG-A nrPDB 32 0.63 4JKL-A nrPDB 31 0.92 5KH2-A nrPDB 31 0.94 3ZMS-C nrPDB 31 0.98 3NJ3-A nrPDB 31 1.0 6ETZ-A nrPDB 31 1.3 1W3H-A nrPDB 31 1.6 6GL0-A nrPDB 30 1.8 3S1J-A nrPDB 30 1.8 5E0C-A nrPDB 30 2.2 1OY5-A nrPDB 30 2.6 6ED2-A nrPDB 30 2.7 4V2X-A nrPDB 29 3.4 4XUF-A nrPDB 29 3.8 3WFX-A nrPDB 29 4.3 3ZPX-A nrPDB 29 4.4 1E3X-A nrPDB 29 4.5 3BH4-A nrPDB 29 4.6 6HA9-A nrPDB 29 4.8 3BES-R nrPDB 29 5.3 5X02-A nrPDB 29 5.6 5KZW-A nrPDB 29 6.3 4RT7-A nrPDB 28 7.5 1KWK-A nrPDB 28 7.9 3K4D-A nrPDB 28 8.2 3RXZ-A nrPDB 28 9.1 5T99-A nrPDB 28 9.4 >3VKK-A nrPDB Length = 469 Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats. Identities = 468/469 (99%), Positives = 469/469 (100%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITIN+ANVLSVMSYDLGMFP Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINQANVLSVMSYDLGMFP 180 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT Sbjct: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI Sbjct: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL Sbjct: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL Sbjct: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 >4GXP-A nrPDB Length = 467 Score = 644 bits (1663), Expect = 0.0, Method: Composition-based stats. Identities = 177/475 (37%), Positives = 264/475 (55%), Gaps = 28/475 (5%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP GF W ATA+YQ+EG ADG G +W TF+H G V TGDVAC Y W+E Sbjct: 12 KFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGN-VKNGDTGDVACDHYNRWKE 70 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ I++LG+ YRFS+SW R+LP+GT G +NQKG+D+YN+IID LL+ G+TP VT++H+ Sbjct: 71 DIEIIEKLGVKAYRFSISWPRILPEGT-GRVNQKGLDFYNRIIDTLLEKGITPFVTIFHW 129 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLP L+ +GG L+ I + F +Y++ F FGDRVK WIT NE ++ Y G F P Sbjct: 130 DLPFALQLKGGLLNREIADWFAEYSRVLFENFGDRVKNWITFNEPLCSAIPGYGSGTFAP 189 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G + HN++ AH R+ + + G + + L + P D +D+E Sbjct: 190 GRQSTS-EPWTVGHNILVAHGRAVKVFRETVK---DGKIGIVLNGDFTYPWDAADPADKE 245 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 AA+R + F FA PI++ GDYP ++ Q+ RLP FT EE+ ++ G+ Sbjct: 246 AAERRLEFFTAWFADPIYL-GDYPASMRKQLG----------DRLPTFTPEERALVHGSN 294 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPS-----WKNVDWIYVVPWGVCKL 356 DF+ + +YT+ I+++ + + + ++ F + W+ G Sbjct: 295 DFYGMNHYTSNYIRHRSSPASADDTVGNVDVLFTNKQGNCIGPETAMPWLRPCAAGFRDF 354 Query: 357 LKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412 L +I Y P IY+TENG D + D R +Y + + A++LD VN++ Sbjct: 355 LVWISKRYGYPPIYVTENGAAFDDVVSEDGRVHDQNRIDYLKAYIGAMVTAVELDGVNVK 414 Query: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 Y WSLLDNFEW +GYS RFG+ +VD+ + R+ S Y+ +++NNGLE Sbjct: 415 GYFVWSLLDNFEWAEGYSKRFGIVYVDYS--TQKRIVKDSGYWYSNVVKNNGLED 467 >5YJ7-A nrPDB Length = 518 Score = 612 bits (1580), Expect = e-176, Method: Composition-based stats. Identities = 194/469 (41%), Positives = 277/469 (59%), Gaps = 24/469 (5%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 AFP GF W AATAAYQ+EG DG+GP +WDTF+ G ++ TGDVAC Y ++E Sbjct: 30 AFPEGFLWGAATAAYQIEGAAAEDGRGPSMWDTFSKIPG-KIDNGDTGDVACDHYHRYKE 88 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+K +K +GL YRFS+SWSR+LP+GT G IN KG+++Y + ++L+ NG+ P VTLYH+ Sbjct: 89 DVKLMKGMGLKSYRFSVSWSRVLPEGT-GAINPKGMEFYQNLTNELIANGIVPTVTLYHW 147 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLP+ L GGWL+E +F +YA F GDRVK W T+NE ++ Y G P Sbjct: 148 DLPEALSKNGGWLNEDTAVAFGQYADVMFQALGDRVKLWFTLNEPWTTAIAGYGQGGHAP 207 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G+ + Y A HN + HA + Y +++KQ G + L W EP ++ D++ Sbjct: 208 GLKNMAENPYMAGHNQLLGHAAAVKVYREKYQEKQGGKIGAVLSTEWKEPL-CHTQEDKD 266 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 AA+R++ ++L FA PI+ GDYPE +K ++ R+P FTE++K+ +KG+A Sbjct: 267 AAERSLIWYLAWFADPIY-KGDYPEEMKERVG----------DRMPAFTEQQKQDLKGSA 315 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKY 359 DFF + +Y T L++ K G D DP W + W+ VVPWG+ +LL++ Sbjct: 316 DFFGINHYATNLLQGPTEKIGAENYFSDLNGWIMMDPRWAVGDASWLSVVPWGMRRLLRW 375 Query: 360 IKDTYNNPVIYITENGF------PQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQV 413 IK Y++PV+Y+TENG + A L+D R +Y + E++KAI DKV + Sbjct: 376 IKHRYDDPVVYVTENGLSVPNESAMTPEAALNDKMRVDYLQGYVAEMWKAINYDKVKVAG 435 Query: 414 YCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 Y WSLLDNFEW+ GY RFGL VD++ + R SAK Y +I Sbjct: 436 YYHWSLLDNFEWSDGYKVRFGLVQVDYK--TQKRTLKESAKVYKDMIAK 482 >2CBU-A nrPDB Length = 468 Score = 602 bits (1552), Expect = e-172, Method: Composition-based stats. Identities = 180/471 (38%), Positives = 268/471 (56%), Gaps = 34/471 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP GF W ATA+YQ+EG ADG G +W TF+H G V TGDVAC Y W+E Sbjct: 27 KFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGN-VKNGDTGDVACDHYNRWKE 85 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ I++LG+ YRFS+SW R+LP+GT G +NQKG+D+YN+IID LL+ G+TP VT+YH+ Sbjct: 86 DIEIIEKLGVKAYRFSISWPRILPEGT-GRVNQKGLDFYNRIIDTLLEKGITPFVTIYHW 144 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLP L+ +GGW + I + F +Y++ F FGDRVK WIT+NE V++++ + G+ P Sbjct: 145 DLPFALQLKGGWANREIADWFAEYSRVLFENFGDRVKNWITLNEPWVVAIVGHLYGVHAP 204 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G+ ++A HNL++AHAR+ + + G + + + EPA D Sbjct: 205 GMRDIYV-AFRAVHNLLRAHARAVKVFRETVK---DGKIGIVFNNGYFEPAS-EKEEDIR 259 Query: 242 AAKRAITFHLD-LFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 A + F+ LF PI+ GDYPE+V + LPE +++ I+ Sbjct: 260 AVRFMHQFNNYPLFLNPIY-RGDYPELVLE----------FAREYLPENYKDDMSEIQEK 308 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DF + YY+ L+K+ + ++ ++ D + W +VP G+ +LK + Sbjct: 309 IDFVGLNYYSGHLVKFDPDAPAKVSFVER-------DLPKTAMGW-EIVPEGIYWILKKV 360 Query: 361 KDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 K+ YN P +YITENG D + D R +Y + + +KAIQ + V L+ Y Sbjct: 361 KEEYNPPEVYITENGAAFDDVVSEDGRVHDQNRIDYLKAHIGQAWKAIQ-EGVPLKGYFV 419 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 WSLLDNFEW +GYS RFG+ +VD+ + R+ S Y+ +++NNGLE Sbjct: 420 WSLLDNFEWAEGYSKRFGIVYVDYS--TQKRIVKDSGYWYSNVVKNNGLED 468 >2DGA-A nrPDB Length = 565 Score = 597 bits (1540), Expect = e-171, Method: Composition-based stats. Identities = 176/483 (36%), Positives = 267/483 (55%), Gaps = 41/483 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 F F + A+T+AYQ+EG W+ DGKGP WD F H ER+ GDVA SY L+EED Sbjct: 74 FDKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHTYPERISDMTNGDVAANSYHLYEED 133 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 +K +K +G+ YRFS+SWSR+LPDGT G +NQ GIDYYNK+I+ L+ N + P VT++H+D Sbjct: 134 VKALKDMGMKVYRFSISWSRILPDGT-GKVNQAGIDYYNKLINSLIDNDIVPYVTIWHWD 192 Query: 123 LPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 PQ LED+ GG+L+ I++ + ++A+ CF FGDRVK W T NE + SY G+ P Sbjct: 193 TPQALEDKYGGFLNRQIVDDYKQFAEVCFKNFGDRVKNWFTFNEPHTYCCFSYGEGIHAP 252 Query: 182 GIPHFG-----------TGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLE 230 G G Y A H+++ AHA + + + + + ++ + E Sbjct: 253 GRCSPGMDCAVPEGDSLREPYTAGHHILLAHAEAVQLFKARYNMHGDSKIGMAFDVMGYE 312 Query: 231 PADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFT 290 P +S D +A +R+I +++ F +P+ + GDYP ++S I RLP FT Sbjct: 313 PYQ-DSFLDDQARERSIDYNMGWFLEPV-VRGDYPFSMRSLIG----------DRLPMFT 360 Query: 291 EEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD------ 344 +EE++ + + D + YYT+R K+ + L + + + + + Sbjct: 361 KEEQEKLASSCDIMGLNYYTSRFSKHVDMSPDFTPTLNTDDAYASSETTGSDGNDIGPIT 420 Query: 345 ---WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQ-----SDPAPLDDTQRWEYFRQT 396 WIY+ P G+ LL +K+ Y NP ++ITENG S P PLDD +R +Y ++ Sbjct: 421 GTYWIYMYPKGLTDLLLIMKEKYGNPPVFITENGIADVEGDESMPDPLDDWKRLDYLQRH 480 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 + AI +++ + W L+DNFEW+ GYSSRFGL ++D D + R SAK + Sbjct: 481 ISAVKDAIDQ-GADVRGHFTWGLIDNFEWSLGYSSRFGLVYIDKNDGNK-RKLKKSAKWF 538 Query: 457 AKI 459 +K Sbjct: 539 SKF 541 >3AIW-A nrPDB Length = 564 Score = 595 bits (1534), Expect = e-170, Method: Composition-based stats. Identities = 177/483 (36%), Positives = 268/483 (55%), Gaps = 41/483 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 F F + A+T+AYQ+EG W+ DGKGP WD F H ER+ GDVA SY ++EED Sbjct: 74 FSKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHTYPERISDGTNGDVAANSYHMYEED 133 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 +K +K +G+ YRFS+SWSR+LP+GT G NQKGIDYYN +I+ L+++G+ P VT++H+D Sbjct: 134 VKALKDMGMKVYRFSISWSRILPNGT-GKPNQKGIDYYNNLINSLIRHGIVPYVTIWHWD 192 Query: 123 LPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 PQ LED+ GG+L + I+ + +A+ CF +FGDRVK W T NE + SY G+ P Sbjct: 193 TPQALEDKYGGFLDKQIVNDYKYFAELCFQSFGDRVKNWFTFNEPHTYCCFSYGEGIHAP 252 Query: 182 GIPHFG-----------TGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLE 230 G G Y A H+++ AHA + + + + K + ++ + E Sbjct: 253 GRCSPGLDCAVPEGDSLREPYTAGHHILLAHAEAVELFKAHYNKHGDSKIGMAFDVMGYE 312 Query: 231 PADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFT 290 P +S D +A +R+I +++ F +P+ + GDYP ++S I RLP FT Sbjct: 313 PYQ-DSFLDDQARERSIDYNMGWFLEPV-VRGDYPFSMRSLIG----------DRLPMFT 360 Query: 291 EEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD------ 344 +EE++ + + D + YYT+R K+ + L + + + + + Sbjct: 361 KEEQEKLASSCDIMGLNYYTSRFSKHVDISSDYTPTLNTDDAYASSETTGSDGNEIGPIT 420 Query: 345 ---WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD-----PAPLDDTQRWEYFRQT 396 WIY+ P G+ LL +K+ Y NP I+ITENG + P PLDD +R +Y ++ Sbjct: 421 GTYWIYMYPKGLTDLLLIMKEKYGNPPIFITENGIADVEGDPEMPDPLDDWKRLDYLQRH 480 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 + AI +++ + W L+DNFEW GYSSRFGL ++D ED + R SAK + Sbjct: 481 ISAVKDAIDQ-GADVRGHFTWGLIDNFEWGSGYSSRFGLVYIDKEDGNK-RKLKKSAKWF 538 Query: 457 AKI 459 AK Sbjct: 539 AKF 541 >3WBE-A nrPDB Length = 489 Score = 594 bits (1531), Expect = e-170, Method: Composition-based stats. Identities = 187/488 (38%), Positives = 272/488 (55%), Gaps = 42/488 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 +FP GF + A+AAYQ EG DG+G +WDTF H G ++ DVA Y +EE Sbjct: 17 SFPEGFVFGTASAAYQYEGAVKEDGRGQTIWDTFAHTFG-KITDFSNADVAVDQYHRFEE 75 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ + +G+ YRFS++WSR+ P+G G +NQ GID+YNK+ID LL G+ P VTLYH+ Sbjct: 76 DIQLMADMGMDAYRFSIAWSRIYPNGV-GQVNQAGIDHYNKLIDALLAKGIQPYVTLYHW 134 Query: 122 DLPQTLEDQG-GWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLPQ LED+ GWL I++ F YA+ CF FGDRVK WIT+N+ + +++ YD G+ Sbjct: 135 DLPQALEDKYKGWLDRQIVDDFAAYAETCFREFGDRVKHWITLNQPHTVAIQGYDAGLQA 194 Query: 181 PGIP-----------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 PG + GT Y AH+ I AHA + Y + ++ Q G + ++ +W Sbjct: 195 PGRCSVLLHLYCKAGNSGTEPYVVAHHFILAHAAAASIYRTKYKATQNGQLGIAFDVMWF 254 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 EP N+ D EAAKRA F L FA P F GDYP +++++ RLP F Sbjct: 255 EPMS-NTTIDIEAAKRAQEFQLGWFADPFFF-GDYPATMRARVG----------ERLPRF 302 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLIKYQE---------NKKGELGILQDAEIEFFPDPSW 340 T +E ++KG DF + +YTT ++ N + G + P Sbjct: 303 TADEAAVVKGALDFVGINHYTTYYTRHNNTNIIGTLLNNTLADTGTVSLPFKNGKPIGDR 362 Query: 341 KNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD------PAPLDDTQRWEYFR 394 N W+Y+VP G+ L+ Y+K+ YN+P +YITENG S+ L D++R +Y Sbjct: 363 ANSIWLYIVPRGMRSLMNYVKERYNSPPVYITENGMDDSNNPFISIKDALKDSKRIKYHN 422 Query: 395 QTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 L +I+ D +++ Y AWSLLDN+EW GYSSRFGL+ VD++D + R P S + Sbjct: 423 DYLTNLAASIKEDGCDVRGYFAWSLLDNWEWAAGYSSRFGLYFVDYKDNLK-RYPKNSVQ 481 Query: 455 EYAKIIRN 462 + +++ Sbjct: 482 WFKALLKT 489 >3WQ4-A nrPDB Length = 507 Score = 593 bits (1530), Expect = e-170, Method: Composition-based stats. Identities = 178/482 (36%), Positives = 265/482 (54%), Gaps = 37/482 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 +FP GF + AA++AYQ EG GKGP +WDTFTH+ ++ TGDVA Y ++E Sbjct: 38 SFPDGFVFGAASSAYQFEGAAKEGGKGPNIWDTFTHEFPGKISNGSTGDVADDFYHRYKE 97 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D+K +K +GL +R S+SW+R+LP G +G +N++GI +YN +I+DLL G+ P +T++H Sbjct: 98 DVKVLKFIGLDGFRMSISWARVLPRGKLSGGVNKEGIAFYNNVINDLLSKGIQPFITIFH 157 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 +DLPQ LED+ GG+LS I+ F +A+ CF FGDRVK WIT+NE S YD G+ Sbjct: 158 WDLPQALEDEYGGFLSPHIVNDFRDFAELCFKEFGDRVKHWITMNEPWSYSYGGYDAGLL 217 Query: 180 PPGIP----------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 PG + GT Y HNL+ +HA + Y ++ QKG + ++L W+ Sbjct: 218 APGRCSAFMAFCPKGNSGTEPYIVTHNLLLSHAAAVKLYKEKYQAYQKGQIGITLVTYWM 277 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 P NS +D++AA+RA+ F F +P+ G+YP+ ++ + RLP F Sbjct: 278 IPYS-NSKADKDAAQRALDFMYGWFIEPLSF-GEYPKSMRRLVGK----------RLPRF 325 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLI-KYQENKKGELGILQDAE------IEFFPDPSWKN 342 T+E+ ++KG+ DF + YY + + L D+ Sbjct: 326 TKEQAMLVKGSFDFLGLNYYIANYVLNVPTSNSVNLSYTTDSLSNQTAFRNGVAIGRPTG 385 Query: 343 VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP----LDDTQRWEYFRQTFQ 398 V ++ P G+ LL Y K+ YN+PVIYITENG ++ + D QR ++ Q Sbjct: 386 VPAFFMYPKGLKDLLVYTKEKYNDPVIYITENGMGDNNNVTTEEGIKDPQRVYFYNQHLL 445 Query: 399 ELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAK 458 L AI V ++ Y W+ LDNFEW GY+ RFG+ +VDF+D + R P SA + K Sbjct: 446 SLKNAIAA-GVKVKGYFTWAFLDNFEWLSGYTQRFGIVYVDFKDGLK-RYPKHSALWFKK 503 Query: 459 II 460 + Sbjct: 504 FL 505 >3PTM-A nrPDB Length = 505 Score = 591 bits (1523), Expect = e-169, Method: Composition-based stats. Identities = 189/485 (38%), Positives = 263/485 (54%), Gaps = 40/485 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 +FP GF + A+++YQ EGG G+GP +WDTFTHQ E++ GDVA SY L++E Sbjct: 33 SFPKGFIFGTASSSYQYEGGAAEGGRGPSIWDTFTHQHPEKIADRSNGDVASDSYHLYKE 92 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D++ +K +G+ YRFS+SW+R+LP+G+ G +N++GI YYN +I++LL GV P +TL+H Sbjct: 93 DVRLMKDMGMDAYRFSISWTRILPNGSLRGGVNKEGIKYYNNLINELLSKGVQPFITLFH 152 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 +D PQ LED+ G+LS II F YA+ CF FGDRVK WIT NE Y G+F Sbjct: 153 WDSPQALEDKYNGFLSPNIINDFKDYAEICFKEFGDRVKNWITFNEPWTFCSNGYATGLF 212 Query: 180 PPGIP-----------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 PG G Y A H+ + AHA + Y + ++ QKG + ++L + W Sbjct: 213 APGRCSPWEKGNCSVGDSGREPYTACHHQLLAHAETVRLYKAKYQALQKGKIGITLVSHW 272 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 P S S+ +AAKRAI F F P+ I GDYP ++ + +RLP+ Sbjct: 273 FVPFS-RSKSNNDAAKRAIDFMFGWFMDPL-IRGDYPLSMRGLVG----------NRLPQ 320 Query: 289 FTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAE-------IEFFPDPSWK 341 FT+E+ K++KG DF + YYT G P Sbjct: 321 FTKEQSKLVKGAFDFIGLNYYTANYADNLPPSNGLNNSYTTDSRANLTGVRNGIPIGPQA 380 Query: 342 NVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP------LDDTQRWEYFRQ 395 W+YV P G LL Y+K+ Y NP +YITENG + + L D R EY+ + Sbjct: 381 ASPWLYVYPQGFRDLLLYVKENYGNPTVYITENGVDEFNNKTLPLQEALKDDARIEYYHK 440 Query: 396 TFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 455 L AI+ D N++ Y AWSLLDNFEW+ GY+ RFG+ VD+ D R R P SA Sbjct: 441 HLLSLLSAIR-DGANVKGYFAWSLLDNFEWSNGYTVRFGINFVDYND-GRKRYPKNSAHW 498 Query: 456 YAKII 460 + K + Sbjct: 499 FKKFL 503 >5OGZ-A nrPDB Length = 456 Score = 590 bits (1522), Expect = e-169, Method: Composition-based stats. Identities = 166/469 (35%), Positives = 253/469 (53%), Gaps = 28/469 (5%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F W +ATAAYQ+EG ++ DGKG +WD F+H G + TGDVAC Y +E Sbjct: 4 ITFPKDFIWGSATAAYQIEGAYNEDGKGESIWDRFSHTPGN-IADGHTGDVACDHYHRYE 62 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED+K +K++G+ YRFS+SW R+ P+GT G +NQKG+D+Y ++ + LL+NG+ P +TLYH Sbjct: 63 EDIKIMKEIGIKSYRFSISWPRIFPEGT-GKLNQKGLDFYKRLTNLLLENGIMPAITLYH 121 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ L+D+GGW + + F +Y++ F GD V W T NE V+S++ + LG+ Sbjct: 122 WDLPQKLQDKGGWKNRDTTDYFTEYSEVIFKNLGDIVPIWFTHNEPGVVSLLGHFLGIHA 181 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGI T + +HNL+ +H ++ + + Q + ++L + PA D Sbjct: 182 PGIKDLRT-SLEVSHNLLLSHGKAVKLFREMNIDAQ---IGIALNLSYHYPAS-EKAEDI 236 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 EAA+ + + + P+ + G YPE + F E++ K+I Sbjct: 237 EAAELSFSLAGRWYLDPV-LKGRYPENALKLYKKKGIELS--------FPEDDLKLISQP 287 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DF A Y++ IKY + + +F ++ WI + P G+ LL + Sbjct: 288 IDFIAFNNYSSEFIKYDPSSESGFSPANSILEKF----EKTDMGWI-IYPEGLYDLLMLL 342 Query: 361 KDTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 Y P I I+ENG D ++DT+R +Y + + +AIQ D VNL+ Y Sbjct: 343 DRDYGKPNIVISENGAAFKDEIGSNGKIEDTKRIQYLKDYLTQAHRAIQ-DGVNLKAYYL 401 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 WSLLDNFEW GY+ RFG+ HV+F+ R S Y ++I+NNG Sbjct: 402 WSLLDNFEWAYGYNKRFGIVHVNFD--TLERKIKDSGYWYKEVIKNNGF 448 >4PTW-A nrPDB Length = 452 Score = 590 bits (1522), Expect = e-169, Method: Composition-based stats. Identities = 159/472 (33%), Positives = 248/472 (52%), Gaps = 28/472 (5%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F W AAT++YQ+EG ++ DGKG +WD F+H G ++ TGD+AC Y L+ Sbjct: 5 IIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPG-KIENGDTGDIACDHYHLYR 63 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ +K++G+ YRFS SW R+LP+G G +NQKG+D+Y +++D+LLK + P++TLYH Sbjct: 64 EDIELMKEIGIRSYRFSTSWPRILPEG-KGRVNQKGLDFYKRLVDNLLKANIRPMITLYH 122 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ L+D+GGW + + F +YA+ F F V W+T NE V++ + G Sbjct: 123 WDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDLWVTHNEPWVVAFEGHAFGNHA 182 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG F T Q AH+L+ +H + + + G + ++L PA +S D Sbjct: 183 PGTKDFKT-ALQVAHHLLLSHGMAVDIFRE---EDLPGEIGITLNLTPAYPAG-DSEKDV 237 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 +AA + F P+F G YPE + + +I Sbjct: 238 KAASLLDDYINAWFLSPVF-KGSYPEELHHIYEQNLGAFTT--------QPGDMDIISRD 288 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DF + YY+ +++++ L +AE+ D + W + P G+ +L + Sbjct: 289 IDFLGINYYSRMVVRHKPGDN-----LFNAEVVKMEDRPSTEMGW-EIYPQGLYDILVRV 342 Query: 361 KDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 Y + +YITENG D + D +R Y F++ +KA++ D V L+ Y Sbjct: 343 NKEYTDKPLYITENGAAFDDKLTEEGKIHDEKRINYLGDHFKQAYKALK-DGVPLRGYYV 401 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 468 WSL+DNFEW GYS RFGL +VD+E+ R R SA Y ++I +EA+ Sbjct: 402 WSLMDNFEWAYGYSKRFGLIYVDYENGNR-RFLKDSALWYREVIEKGQVEAN 452 >3VIK-A nrPDB Length = 487 Score = 589 bits (1519), Expect = e-169, Method: Composition-based stats. Identities = 218/469 (46%), Positives = 296/469 (63%), Gaps = 9/469 (1%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F AATA+YQ+EG WD +GKGP +WDT TH+ + V TGD+A SY L++E Sbjct: 11 TFPDEFKLGAATASYQIEGAWDENGKGPNIWDTLTHEHPDYVVDGATGDIADDSYHLYKE 70 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+K +K+LG YRFS+SW+R+LP+G +NQ GIDYYN +I++LL NG+ P+VT+YH+ Sbjct: 71 DVKILKELGAQVYRFSISWARVLPEGHDNIVNQDGIDYYNNLINELLANGIEPMVTMYHW 130 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGM-FP 180 DLPQ L+D GGW + + + + YA+ F FGDRVK W+T N + Y + Sbjct: 131 DLPQALQDLGGWPNLVLAKYSENYARVLFKNFGDRVKLWLTFNSPLTF-MDGYASEIGMA 189 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 P I G G Y AAH +I AHAR +H YD FR +Q G V +SL W EPA NS D+ Sbjct: 190 PSINTPGIGDYLAAHTVIHAHARIYHLYDQEFRAEQGGKVGISLNINWCEPAT-NSAEDR 248 Query: 241 EAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKG 299 + + F+L L+A PIF +GDYP V+K +++ S +GY SRLP+FT EE + I+G Sbjct: 249 ASCENYQQFNLGLYAHPIFTEEGDYPAVLKDRVSRNSADEGYTDSRLPQFTAEEVEYIRG 308 Query: 300 TADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSW--KNVDWIYVVPWGVCKLL 357 T DF + +YT L K + E +D+ + D +W W+ VVPWG K L Sbjct: 309 THDFLGINFYTALLGK-SGVEGYEPSRYRDSGVILTQDAAWPISASSWLKVVPWGFRKEL 367 Query: 358 KYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 +IK+ YNNP ++ITENGF SD L+DT R Y+ + +E+ KAI D VN+ Y AW Sbjct: 368 NWIKNEYNNPPVFITENGF--SDYGGLNDTGRVHYYTEHLKEMLKAIHEDGVNVIGYTAW 425 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 SL+DNFEW +GYS +FG++ VDFEDPARPR+P SAK A+I+ + Sbjct: 426 SLMDNFEWLRGYSEKFGIYAVDFEDPARPRIPKESAKVLAEIMNTRKIP 474 >3AHX-A nrPDB Length = 453 Score = 589 bits (1519), Expect = e-169, Method: Composition-based stats. Identities = 166/471 (35%), Positives = 245/471 (52%), Gaps = 32/471 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F + ATAAYQ+EG + D KG +WD F+H G V K GD+AC Y ++ Sbjct: 4 LRFPKDFIFGTATAAYQIEGAYKEDEKGESIWDRFSHIPGN-VAKMHNGDIACDHYHRYK 62 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ +K LG+ YRFS++W R+ P G G INQKGI +Y +ID+L+KN + P +T+YH Sbjct: 63 EDVQLLKSLGIKSYRFSIAWPRIFPKGF-GEINQKGIQFYRDLIDELIKNDIEPAITIYH 121 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ L+D GGW + + + + YA F FGDRVK WIT NE V S + Y LG+ Sbjct: 122 WDLPQKLQDIGGWANPQVADYYVDYANLLFREFGDRVKTWITHNEPWVASYLGYALGVHA 181 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGI AAHN++ +H ++ +Y L +Q G + ++L + D Sbjct: 182 PGIKDMKM-ALLAAHNILLSHFKAVKAYREL---EQDGQIGITLNLSTCYS-NSADEEDI 236 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 AA R+ ++ F + G YPE + + ++ +PE +E + T Sbjct: 237 AAAHRSDGWNNRWFLDAA-LKGTYPEDMIKIFSD--------TNIMPELPKELFTEVFET 287 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 +DF + YYT +++K AE +P + W + P G+ LL I Sbjct: 288 SDFLGINYYTRQVVKNNSEA------FIGAESVAMDNP-KTEMGW-EIYPQGLYDLLTRI 339 Query: 361 KDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 Y N +YITENG +D ++D R +Y F AI+ V L+ Y Sbjct: 340 HRDYGNIDLYITENGAAFNDMVNRDGKVEDENRLDYLYTHFAAALSAIEA-GVPLKGYYI 398 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII-RNNGLE 466 WS +DNFEW +GY RFG+ HV+++ + R SA Y ++I R+N LE Sbjct: 399 WSFMDNFEWAEGYEKRFGIVHVNYK--TQERTIKKSAYWYKELIERSNKLE 447 >3ZJ8-A nrPDB Length = 532 Score = 588 bits (1516), Expect = e-168, Method: Composition-based stats. Identities = 174/480 (36%), Positives = 268/480 (55%), Gaps = 36/480 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + A +AYQ EG ++ +GP +WDTFT + ++ G+ A Y +++ED Sbjct: 43 FPQDFIFGAGGSAYQCEGAYNEGNRGPSIWDTFTQRSPAKISDGSNGNQAINCYHMYKED 102 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 +K +KQ GL YRFS+SWSR+LP G +N+ G+ +Y+ ID+LL NG+ P VTL+H+ Sbjct: 103 IKIMKQTGLESYRFSISWSRVLPGGRLAAGVNKDGVKFYHDFIDELLANGIKPSVTLFHW 162 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLPQ LED+ GG+LS I++ F +YA+FCF FGD++K W T NE + +V Y LG F Sbjct: 163 DLPQALEDEYGGFLSHRIVDDFCEYAEFCFWEFGDKIKYWTTFNEPHTFAVNGYALGEFA 222 Query: 181 PGI------PHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADP 234 PG Y HN++ AH + Y + F+K Q+G + + L ++W+EP Sbjct: 223 PGRGGKGDEGDPAIEPYVVTHNILLAHKAAVEEYRNKFQKCQEGEIGIVLNSMWMEPLS- 281 Query: 235 NSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294 + +D +A KRA+ F L F +P+ GDYP+ ++ + RLP+F+ ++ Sbjct: 282 DVQADIDAQKRALDFMLGWFLEPL-TTGDYPKSMRELV----------KGRLPKFSADDS 330 Query: 295 KMIKGTADFFAVQYYTTRLI-KYQENKKGELGILQDAEIEFFPDPSWKNV------DWIY 347 + +KG DF + YYT + ++ +L D ++ + + K + W + Sbjct: 331 EKLKGCYDFIGMNYYTATYVTNAVKSNSEKLSYETDDQVTKTFERNQKPIGHALYGGWQH 390 Query: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPL------DDTQRWEYFRQTFQELF 401 VVPWG+ KLL Y K+TY+ PV+Y+TE+G + + + D +R +Y ++ + Sbjct: 391 VVPWGLYKLLVYTKETYHVPVLYVTESGMVEENKTKILLSEARRDAERTDYHQKHLASVR 450 Query: 402 KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 461 AI D VN++ Y WS DNFEWN GY R+G+ HVD++ R P SA Y I Sbjct: 451 DAID-DGVNVKGYFVWSFFDNFEWNLGYICRYGIIHVDYKS--FERYPKESAIWYKNFIA 507 >1QOX-A nrPDB Length = 449 Score = 587 bits (1513), Expect = e-168, Method: Composition-based stats. Identities = 167/468 (35%), Positives = 252/468 (53%), Gaps = 28/468 (5%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP+ F W ATAAYQ+EG ++ DG+G +WDTF H G +V G+VAC SY EED Sbjct: 5 FPSDFKWGVATAAYQIEGAYNEDGRGMSIWDTFAHTPG-KVKNGDNGNVACDSYHRVEED 63 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +K LG+ YRFS+SW R+LP GT G +N+ G+DYY++++D+LL NG+ P TLYH+D Sbjct: 64 VQLLKDLGVKVYRFSISWPRVLPQGT-GEVNRAGLDYYHRLVDELLANGIEPFCTLYHWD 122 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L+DQGGW S I++F +YA+ F G ++KQWIT NE ++ +S LG+ PG Sbjct: 123 LPQALQDQGGWGSRITIDAFAEYAELMFKELGGKIKQWITFNEPWCMAFLSNYLGVHAPG 182 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 +H+L+ AH R+ + L G + ++ W P + D EA Sbjct: 183 NKDLQL-AIDVSHHLLVAHGRAVTLFREL---GISGEIGIAPNTSWAVPYR-RTKEDMEA 237 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 R + D + PI+ G+YP+ + ++ K P + + ++I D Sbjct: 238 CLRVNGWSGDWYLDPIYF-GEYPKFMLDWYENLGYK--------PPIVDGDMELIHQPID 288 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKD 362 F + YYT+ + +Y + G + + + ++ W + G+ LL+Y D Sbjct: 289 FIGINYYTSSMNRYNPGEAGGMLSSEAISMGA----PKTDIGW-EIYAEGLYDLLRYTAD 343 Query: 363 TYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWS 418 Y NP +YITENG +D + D +R +Y + +AI+ D +NL+ Y WS Sbjct: 344 KYGNPTLYITENGACYNDGLSLDGRIHDQRRIDYLAMHLIQASRAIE-DGINLKGYMEWS 402 Query: 419 LLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 L+DNFEW +GY RFGL HVD++ R P S Y +I L+ Sbjct: 403 LMDNFEWAEGYGMRFGLVHVDYD--TLVRTPKDSFYWYKGVISRGWLD 448 >4MDP-A nrPDB Length = 499 Score = 584 bits (1507), Expect = e-167, Method: Composition-based stats. Identities = 174/480 (36%), Positives = 252/480 (52%), Gaps = 37/480 (7%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 M+ P F W ATAAYQ+EG + DG+GP +WDTF G ++ +G VAC SY + Sbjct: 24 MSLPPDFKWGFATAAYQIEGSVNEDGRGPSIWDTFCAIPG-KIADGSSGAVACDSYKRTK 82 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLP-DGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 ED+ +K+LG YRFS+SWSR++P G INQKGID+Y K +DDL++ G+TP +TL+ Sbjct: 83 EDIALLKELGANSYRFSISWSRIIPLGGRNDPINQKGIDHYVKFVDDLIEAGITPFITLF 142 Query: 120 HFDLPQTLEDQ-GGWLS-EAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLG 177 H+DLP L+ + GG+L+ E F+ YA+ F + K WIT NE +++ Y+ G Sbjct: 143 HWDLPDALDKRYGGFLNKEEFAADFENYARIMFKAI-PKCKHWITFNEPWCSAILGYNTG 201 Query: 178 MFPPGIP---------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 F PG + HN++ AHAR+ +Y F+ Q G + ++L Sbjct: 202 YFAPGHTSDRSKSPVGDSAREPWIVGHNILIAHARAVKAYREDFKPTQGGEIGITLNGDA 261 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 P DP +D EA R I F + FA PI+ G YP+ ++ Q+ RLPE Sbjct: 262 TLPWDPEDPADIEACDRKIEFAISWFADPIYF-GKYPDSMRKQLG----------DRLPE 310 Query: 289 FTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPS-----WKNV 343 FT EE ++KG+ DF+ + +YT IK++ E L + E F+ Sbjct: 311 FTPEEVALVKGSNDFYGMNHYTANYIKHKTGVPPEDDFLGNLETLFYNKYGDCIGPETQS 370 Query: 344 DWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP------LDDTQRWEYFRQTF 397 W+ G LL ++ Y P IY+TENG L+D R +YF Sbjct: 371 FWLRPHAQGFRDLLNWLSKRYGYPKIYVTENGTSLKGENDMPLEQVLEDDFRVKYFNDYV 430 Query: 398 QELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYA 457 + + A+ D N++ Y AWSLLDNFEW +GY +RFG+ +VD+ + + R P SAK Sbjct: 431 RAMAAAVAEDGCNVRGYLAWSLLDNFEWAEGYETRFGVTYVDYAND-QKRYPKKSAKSLK 489 >1V02-A nrPDB Length = 565 Score = 583 bits (1503), Expect = e-167, Method: Composition-based stats. Identities = 171/485 (35%), Positives = 259/485 (53%), Gaps = 43/485 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + AAT+AYQ+EG W+ DGKGP WD F H E + GDVA SY ++ ED Sbjct: 76 FPPSFLFGAATSAYQIEGAWNEDGKGPSTWDHFCHNFPEWIVDRSNGDVAADSYHMYAED 135 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 ++ +K++G+ YRFS+SW R+LP GT G IN+K ++YYNK+ID LL+NG+ P +T++H+ Sbjct: 136 VRLLKEMGMDAYRFSISWPRILPKGTLAGGINEKRVEYYNKLIDLLLENGIEPYITIFHW 195 Query: 122 DLPQTLED-QGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 D PQ L D GG+L E II+ + +A+ CF FG VK W+T NE +SY G+ Sbjct: 196 DTPQALVDAYGGFLDERIIKDYTDFAKVCFEKFGKTVKNWLTFNEPETFCSVSYGTGVLA 255 Query: 181 PGIPHFG-----------TGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWL 229 PG G + Y AHNL++AHA + Y+ + K G + L+L Sbjct: 256 PGRCSPGVSCAVPTGNSLSEPYIVAHNLLRAHAETVDIYN-KYHKGADGRIGLALNVFGR 314 Query: 230 EPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF 289 P N+ DQ+A +R++ L F +P+ + GDYP ++ R+P F Sbjct: 315 VPYT-NTFLDQQAQERSMDKCLGWFLEPV-VRGDYPFSMR----------VSARDRVPYF 362 Query: 290 TEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD----- 344 E+E++ + G+ D + YYT+ K+ + +L + + + + Sbjct: 363 KEKEQEKLVGSYDMIGINYYTSTFSKHIDLSPNNSPVLNTDDAYASQETKGPDGNAIGPP 422 Query: 345 ----WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP------LDDTQRWEYFR 394 WI + P G+ +L +K+ Y NP +YITENG D L+D R +Y + Sbjct: 423 TGNAWINMYPKGLHDILMTMKNKYGNPPMYITENGMGDIDKGDLPKPVALEDHTRLDYIQ 482 Query: 395 QTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 454 + L ++I L +++ Y AWSLLDNFEW+ GY+ RFG+ +VD E+ R SA+ Sbjct: 483 RHLSVLKQSIDL-GADVRGYFAWSLLDNFEWSSGYTERFGIVYVDRENGC-ERTMKRSAR 540 Query: 455 EYAKI 459 + Sbjct: 541 WLQEF 545 >1WCG-A nrPDB Length = 464 Score = 582 bits (1502), Expect = e-167, Method: Composition-based stats. Identities = 182/465 (39%), Positives = 270/465 (58%), Gaps = 9/465 (1%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F + +TA+YQ+EGGW+ DGKG +WD H E + GD+AC SY ++E Sbjct: 4 KFPKDFMFGTSTASYQIEGGWNEDGKGENIWDRLVHTSPEVIKDGTNGDIACDSYHKYKE 63 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+ IK L L YRFS+SW+R+ P G + KGI YYN +I++L+KN + P+VT+YH+ Sbjct: 64 DVAIIKDLNLKFYRFSISWARIAPSGVMNSLEPKGIAYYNNLINELIKNDIIPLVTMYHW 123 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLPQ L+D GGW++ + + F +YA+ F+ FGDRVK WIT NE + Y + + P Sbjct: 124 DLPQYLQDLGGWVNPIMSDYFKEYARVLFTYFGDRVKWWITFNEP-IAVCKGYSIKAYAP 182 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 + TG Y A H + AH +++ Y+ +F+ Q G +S+S+ V+ P + S D E Sbjct: 183 NLNLKTTGHYLAGHTQLIAHGKAYRLYEEMFKPTQNGKISISISGVFFMPKNAESDDDIE 242 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 A+RA F F P++ GDYP ++K + S+++G P S+LP+FT++E K++KGTA Sbjct: 243 TAERANQFERGWFGHPVY-KGDYPPIMKKWVDQKSKEEGLPWSKLPKFTKDEIKLLKGTA 301 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSW---KNVDWIYVVPWGVCKLLK 358 DF+A+ +Y++RL+ + + DA D +W +I VP G+ KLL Sbjct: 302 DFYALNHYSSRLVTFGSDPNPNFN--PDASYVTSVDEAWLKPNETPYIIPVPEGLRKLLI 359 Query: 359 YIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWS 418 ++K+ Y NP + ITENG+ D LDD ++ Y + +A+ DK N+ Y WS Sbjct: 360 WLKNEYGNPQLLITENGYG--DDGQLDDFEKISYLKNYLNATLQAMYEDKCNVIGYTVWS 417 Query: 419 LLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 LLDNFEW GYS FGL +DF DP R R S + ++ Sbjct: 418 LLDNFEWFYGYSIHFGLVKIDFNDPQRTRTKRESYTYFKNVVSTG 462 >5IDI-A nrPDB Length = 452 Score = 582 bits (1502), Expect = e-167, Method: Composition-based stats. Identities = 175/471 (37%), Positives = 264/471 (56%), Gaps = 34/471 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP GF W ATA+YQ+EG ADG G +W TF+H G V TGDVAC Y W+E Sbjct: 3 KFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGN-VKNGDTGDVACDHYNRWKE 61 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ I+++G YRFS+SW R+LP+GT G +NQKG+D+YN+IID LL+ +TP +T+YH+ Sbjct: 62 DIEIIEKIGAKAYRFSISWPRILPEGT-GKVNQKGLDFYNRIIDTLLEKNITPFITIYHW 120 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLP +L+ +GGW + I + F +Y++ F FGDRVK WIT+NE V++++ + G+ P Sbjct: 121 DLPFSLQLKGGWANRDIADWFAEYSRVLFENFGDRVKHWITLNELWVVAIVGHLYGVHAP 180 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G+ + HNL++AHA+S + + G + + + EPA D Sbjct: 181 GMKDIYV-AFHTVHNLLRAHAKSVKVFRETVK---DGKIGIVFNNGYFEPAS-EREEDIR 235 Query: 242 AAKRAITFHLD-LFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 AA+ F+ LF PI+ G+YP++V + LP E++ + IK Sbjct: 236 AARFMHQFNNYPLFLNPIY-RGEYPDLVLE----------FAREYLPRNYEDDMEEIKQE 284 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DF + YY+ ++KY N + ++ + + W +VP G+ +LK + Sbjct: 285 IDFVGLNYYSGHMVKYDPNSPARVSFVER-------NLPKTAMGW-EIVPEGIYWILKGV 336 Query: 361 KDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 K+ YN +YIT NG D + D R +Y R +++++AIQ D V L+ Y Sbjct: 337 KEEYNPQEVYITGNGAAFDDVVSEGGKVHDQNRIDYLRAHIEQVWRAIQ-DGVPLKGYFV 395 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 WSLLDNFEW +GYS RFG+ +VD+ + R+ S Y+ +I+NNGL Sbjct: 396 WSLLDNFEWAEGYSKRFGIVYVDYN--TQKRIIKDSGYWYSNVIKNNGLTD 444 >4A3Y-A nrPDB Length = 540 Score = 582 bits (1501), Expect = e-166, Method: Composition-based stats. Identities = 197/498 (39%), Positives = 274/498 (55%), Gaps = 58/498 (11%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FPA F ++AYQ+EGG G+GP +WDTFTH+ + + GDVA SY L++ED Sbjct: 22 FPADFIMGTGSSAYQIEGGARDGGRGPSIWDTFTHRRPDMIRGGTNGDVAVDSYHLYKED 81 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + +K LGL YRFS+SWSR+LP G +G +N++GI+YYN +ID LL NG+ P VTL+H+ Sbjct: 82 VNILKNLGLDAYRFSISWSRVLPGGRLSGGVNKEGINYYNNLIDGLLANGIKPFVTLFHW 141 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 D+PQ LED+ GG+LS I++ F +YA+ CF FGDRVK W+T+NE SV Y G++ Sbjct: 142 DVPQALEDEYGGFLSPRIVDDFCEYAELCFWEFGDRVKHWMTLNEPWTFSVHGYATGLYA 201 Query: 181 PGI----------------------------PHFGTGGYQAAHNLIKAHARSWHSYDSLF 212 PG + GT Y H+L+ AHA + Y + F Sbjct: 202 PGRGRTSPEHVNHPTVQHRCSTVAPQCICSTGNPGTEPYWVTHHLLLAHAAAVELYKNKF 261 Query: 213 RKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQI 272 ++ Q+G + +S W+EP D NS SD EAA RA+ F L F +PI GDYP+ +K + Sbjct: 262 QRGQEGQIGISHATQWMEPWDENSASDVEAAARALDFMLGWFMEPI-TSGDYPKSMKKFV 320 Query: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLI-KYQENKKGELGILQDAE 331 S RLP+F+ E+ KM+KG+ DF + YYT + N G + + Sbjct: 321 GS----------RLPKFSPEQSKMLKGSYDFVGLNYYTASYVTNASTNSSGSNNFSYNTD 370 Query: 332 I--------EFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP 383 I P DW+ + P G+ K+L Y K TYN P+IY+TENG Sbjct: 371 IHVTYETDRNGVPIGPQSGSDWLLIYPEGIRKILVYTKKTYNVPLIYVTENGVDDVKNTN 430 Query: 384 L------DDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFH 437 L D+ R +Y + + +A+ D VN++ Y AWSLLDNFEW +GY RFG+ H Sbjct: 431 LTLSEARKDSMRLKYLQDHIFNVRQAMN-DGVNVKGYFAWSLLDNFEWGEGYGVRFGIIH 489 Query: 438 VDFEDPARPRVPYTSAKE 455 +D+ D R P SA Sbjct: 490 IDYNDN-FARYPKDSAVW 506 >5BWF-A nrPDB Length = 485 Score = 579 bits (1492), Expect = e-165, Method: Composition-based stats. Identities = 169/469 (36%), Positives = 247/469 (52%), Gaps = 29/469 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 P F W ATAAYQ+EG D DG+GP +WDTF G ++ +G AC SY ED Sbjct: 22 LPKDFQWGFATAAYQIEGAIDKDGRGPSIWDTFCAIPG-KIADGTSGVTACDSYNRTAED 80 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDG-TTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + +K LG YRFS+SWSR++P G +NQ GID+Y + +DDLL+ G+TP +TL+H+ Sbjct: 81 IALLKSLGAKSYRFSISWSRIIPKGGRDDPVNQLGIDHYAQFVDDLLEAGITPFITLFHW 140 Query: 122 DLPQTLEDQ-GGWLSE-AIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 DLP+ L + GG L+ F+ YA+ F +V+ WIT NE ++ Y G F Sbjct: 141 DLPEELHQRYGGLLNRTEFPLDFENYARVMFKAL-PKVRNWITFNEPLCSAIPGYGSGTF 199 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSD 239 PG T + HNL+ AH R+ Y F+ G + + L + P D + D Sbjct: 200 APGRQS-TTEPWIVGHNLLVAHGRAVKVYRDEFKDLNDGQIGIVLNGDFTYPWDSSDPLD 258 Query: 240 QEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKG 299 +EAA+R + F +A PI++ GDYP ++ Q+ RLPEFT EEK + G Sbjct: 259 REAAERRLEFFTAWYADPIYL-GDYPASMRKQLG----------DRLPEFTPEEKAFVLG 307 Query: 300 TADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSW-----KNVDWIYVVPWGVC 354 + DF+ + +YT+ I+++ + + + ++ F+ W+ P G Sbjct: 308 SNDFYGMNHYTSNYIRHRTSPATADDTVGNVDVLFYNKEGQCIGPETESSWLRPCPAGFR 367 Query: 355 KLLKYIKDTYNNPVIYITENGFPQSDPAPL------DDTQRWEYFRQTFQELFKAIQLDK 408 L +I YN P IY+TENG L +D R Y+ + + +F A LD Sbjct: 368 DFLVWISKRYNYPKIYVTENGTSLKGENDLPKEKILEDDFRVNYYNEYIRAMFTAATLDG 427 Query: 409 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYA 457 VN++ Y AWSL+DNFEW GY +RFG+ +VD+E+ + R P SAK Sbjct: 428 VNVKGYFAWSLMDNFEWADGYVTRFGVTYVDYEN-GQQRFPKKSAKSLK 475 >3AHY-A nrPDB Length = 473 Score = 579 bits (1492), Expect = e-165, Method: Composition-based stats. Identities = 166/470 (35%), Positives = 249/470 (52%), Gaps = 30/470 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 P F W ATAAYQ+EG D DG+GP +WDTF Q G ++ +G AC SY ED Sbjct: 9 LPKDFQWGFATAAYQIEGAVDQDGRGPSIWDTFCAQPG-KIADGSSGVTACDSYNRTAED 67 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTG-FINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 + +K LG YRFS+SWSR++P+G G +NQ GID+Y K +DDLL G+TP +TL+H+ Sbjct: 68 IALLKSLGAKSYRFSISWSRIIPEGGRGDAVNQAGIDHYVKFVDDLLDAGITPFITLFHW 127 Query: 122 DLPQTLEDQ-GGWLSE-AIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 DLP+ L + GG L+ F+ YA+ F +V+ WIT NE ++ Y G F Sbjct: 128 DLPEGLHQRYGGLLNRTEFPLDFENYARVMFRAL-PKVRNWITFNEPLCSAIPGYGSGTF 186 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRK-KQKGMVSLSLFAVWLEPADPNSVS 238 PG + HN++ AH R+ +Y F+ G + + L + P D + Sbjct: 187 APGRQSTS-EPWTVGHNILVAHGRAVKAYRDDFKPASGDGQIGIVLNGDFTYPWDAADPA 245 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298 D+EAA+R + F FA PI++ GDYP ++ Q+ RLP FT EE+ ++ Sbjct: 246 DKEAAERRLEFFTAWFADPIYL-GDYPASMRKQLG----------DRLPTFTPEERALVH 294 Query: 299 GTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPS-----WKNVDWIYVVPWGV 353 G+ DF+ + +YT+ I+++ + + + ++ F W+ G Sbjct: 295 GSNDFYGMNHYTSNYIRHRSSPASADDTVGNVDVLFTNKQGNCIGPETQSPWLRPCAAGF 354 Query: 354 CKLLKYIKDTYNNPVIYITENGFPQSDPAPL------DDTQRWEYFRQTFQELFKAIQLD 407 L +I Y P IY+TENG + L +D R +Y+ + + + A++LD Sbjct: 355 RDFLVWISKRYGYPPIYVTENGTSIKGESDLPKEKILEDDFRVKYYNEYIRAMVTAVELD 414 Query: 408 KVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYA 457 VN++ Y AWSL+DNFEW GY +RFG+ +VD+E+ + R P SAK Sbjct: 415 GVNVKGYFAWSLMDNFEWADGYVTRFGVTYVDYEN-GQKRFPKKSAKSLK 463 >2RGL-A nrPDB Length = 481 Score = 578 bits (1491), Expect = e-165, Method: Composition-based stats. Identities = 187/480 (38%), Positives = 271/480 (56%), Gaps = 36/480 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 AFP F + T+AYQVEG + G+GP +WD F H G V NQ GDVA Y ++E Sbjct: 19 AFPKRFVFGTVTSAYQVEGMAASGGRGPSIWDAFAHTPGN-VAGNQNGDVATDQYHRYKE 77 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+ +K L YRFS+SWSR+ PDG G +NQ+G+ YYN +I+ LL+ G+TP V LYH+ Sbjct: 78 DVNLMKSLNFDAYRFSISWSRIFPDG-EGRVNQEGVAYYNNLINYLLQKGITPYVNLYHY 136 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP LE + GGWL+ + + F +YA FCF TFG+RVK W T NE +++++ YD G P Sbjct: 137 DLPLALEKKYGGWLNAKMADLFTEYADFCFKTFGNRVKHWFTFNEPRIVALLGYDQGTNP 196 Query: 181 PGIP-------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPAD 233 P + T Y AHN + +HA + Y + ++ Q+G V + L W E Sbjct: 197 PKRCTKCAAGGNSATEPYIVAHNFLLSHAAAVARYRTKYQAAQQGKVGIVLDFNWYEALS 256 Query: 234 PNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEE 293 NS DQ AA+RA FH+ + P+ I+G YP++++ + RLP+FT E+ Sbjct: 257 -NSTEDQAAAQRARDFHIGWYLDPL-INGHYPQIMQDLV----------KDRLPKFTPEQ 304 Query: 294 KKMIKGTADFFAVQYYTTRLIKYQE-NKKGELGILQDAEIEFF------PDPSWKNVDWI 346 +++KG+AD+ + YT +K Q+ ++ D ++ + P N +W+ Sbjct: 305 ARLVKGSADYIGINQYTASYMKGQQLMQQTPTSYSADWQVTYVFAKNGKPIGPQANSNWL 364 Query: 347 YVVPWGVCKLLKYIKDTYNNPVIYITENGFPQ----SDPAPLDDTQRWEYFRQTFQELFK 402 Y+VPWG+ + YIK Y NP + ITENG Q S L DT R ++R +L K Sbjct: 365 YIVPWGMYGCVNYIKQKYGNPTVVITENGMDQPANLSRDQYLRDTTRVHFYRSYLTQLKK 424 Query: 403 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 AI + N+ Y AWSLLDNFEW GY+S+FG+ +VDF R P SA + ++++ Sbjct: 425 AID-EGANVAGYFAWSLLDNFEWLSGYTSKFGIVYVDFN--TLERHPKASAYWFRDMLKH 481 >1BGG-A nrPDB Length = 448 Score = 576 bits (1484), Expect = e-164, Method: Composition-based stats. Identities = 166/468 (35%), Positives = 251/468 (53%), Gaps = 30/468 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W ATAAYQ+EG + DG+G +WDTF H G +VF G+VAC SY +EED Sbjct: 6 FPQDFMWGTATAAYQIEGAYQEDGRGLSIWDTFAHTPG-KVFNGDNGNVACDSYHRYEED 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +K+LG+ YRFS+SW R+ P+G G +NQ+G+DYY++++D L NG+ P TLYH+D Sbjct: 65 IRLMKELGIRTYRFSVSWPRIFPNGD-GEVNQEGLDYYHRVVDLLNDNGIEPFCTLYHWD 123 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L+D GGW + I++F ++A+ F F +++ W+T NE ++ +S LG+ PG Sbjct: 124 LPQALQDAGGWGNRRTIQAFVQFAETMFREFHGKIQHWLTFNEPWCIAFLSNMLGVHAPG 183 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + + T H+L+ AH S + L G + ++ W P S D+ A Sbjct: 184 LTNLQT-AIDVGHHLLVAHGLSVRRFREL---GTSGQIGIAPNVSWAVPYS-TSEEDKAA 238 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 R I+ H D F +PI+ G YP+ + A + + +I D Sbjct: 239 CARTISLHSDWFLQPIY-QGSYPQFLVDWFAEQGATVP--------IQDGDMDIIGEPID 289 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKD 362 + YY+ + ++ E G LQ EI ++ W V G+ ++L Y++ Sbjct: 290 MIGINYYSMSVNRFNP----EAGFLQSEEINMG--LPVTDIGWP-VESRGLYEVLHYLQ- 341 Query: 363 TYNNPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSL 419 Y N IYITENG +D + D +R Y +Q ++ + I D ++++ Y AWSL Sbjct: 342 KYGNIDIYITENGACINDEVVNGKVQDDRRISYMQQHLVQVHRTIH-DGLHVKGYMAWSL 400 Query: 420 LDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 LDNFEW +GY+ RFG+ HVDF + R P S Y ++ NN LE Sbjct: 401 LDNFEWAEGYNMRFGMIHVDF--RTQVRTPKESYYWYRNVVSNNWLET 446 >4HZ6-A nrPDB Length = 444 Score = 575 bits (1483), Expect = e-164, Method: Composition-based stats. Identities = 173/471 (36%), Positives = 257/471 (54%), Gaps = 35/471 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP GF W AAT++YQ+EG W+ DGKG +WD FT G ++ +GDVAC Y +E+ Sbjct: 4 KFPEGFLWGAATSSYQIEGAWNEDGKGESIWDRFTRIPG-KIKNGDSGDVACDHYHRYEQ 62 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL ++QLGL YRFS++W+R+ PD ++ INQ+G+D+Y ++++ L K + P+ TLYH+ Sbjct: 63 DLDLMRQLGLKTYRFSIAWARIQPD-SSRQINQRGLDFYRRLVEGLHKRDILPMATLYHW 121 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLPQ +ED+GGWLS F +Y + GD++ W+T NE V Y +G+F P Sbjct: 122 DLPQWVEDEGGWLSRESASRFAEYTHALVAALGDQIPLWVTHNEPMVTVWAGYHMGLFAP 181 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G+ GG + AH+L+ +H ++ ++ +L + ++L+ ++ A+P +D E Sbjct: 182 GLKDPTLGG-RVAHHLLLSHGQALQAFRALSPAGSQMGITLNFNTIYPVSAEP---ADVE 237 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEF-TEEEKKMIKGT 300 AA+R +F +LF +P+ I G Y +Q LPEF E+ + I Sbjct: 238 AARRMHSFQNELFLEPL-IRGQY-----------NQATLMAYPNLPEFIAPEDMQTISAP 285 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DF V YY +K G + ++ + + W + P G+ LL I Sbjct: 286 IDFLGVNYYNPMRVKSSPQPPGIEVVQVESPV--------TAMGW-EIAPEGLYDLLMGI 336 Query: 361 KDTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 TY IYITENG D ++D QR YF+ +A+ D V+L+ Y A Sbjct: 337 TRTYGKLPIYITENGAAFDDQPDQSGQVNDPQRVGYFQGHIGAARRALA-DGVDLRGYYA 395 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 WSLLDNFEW +GYS RFG+ +VDFE + R SA+ Y +I NNGLE Sbjct: 396 WSLLDNFEWAEGYSKRFGIIYVDFE--TQQRTLKQSAQWYRDVIANNGLED 444 >5CG0-A nrPDB Length = 489 Score = 573 bits (1478), Expect = e-164, Method: Composition-based stats. Identities = 191/473 (40%), Positives = 274/473 (57%), Gaps = 9/473 (1%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F + ATA+YQ+EG WD DGKG +WD H E + GD+A SY ++ D Sbjct: 5 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMVHNTPEVIRDLSNGDIAADSYHNYKRD 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +++LGL YRFSLSW+R+LP G +N GI +YN ID++LK +TP++TLYH+D Sbjct: 65 VEMMRELGLDAYRFSLSWARILPTGMANEVNPAGIAFYNNYIDEMLKYNITPLITLYHWD 124 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ L++ GG+ + I + F+ YA+ F FGDRVK +IT NE + Y P Sbjct: 125 LPQKLQELGGFANPLISDWFEDYARVVFENFGDRVKMFITFNEPREICFEGYGSATKAPI 184 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + G Y A NL+ AHA++++ YD FR Q G +++ W PA P + D+ A Sbjct: 185 LNATAMGAYLCAKNLVTAHAKAYYLYDREFRPVQGGQCGITISVNWFGPATP-TPEDEMA 243 Query: 243 AKRAITFHLDLFAKPIF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 A+ ++A PIF +G +P+ + +IA S +QGYP SRLPEFTEEEK ++GT+ Sbjct: 244 AELRRQGEWGIYAHPIFSAEGGFPKELSDKIAEKSAQQGYPWSRLPEFTEEEKAFVRGTS 303 Query: 302 DFFAVQYYTTRLIKYQE--NKKGELGILQDAEIEFFPDPSW--KNVDWIYVVPWGVCKLL 357 DFF V +YT L+ E +L D + + D SW W+ + P + L Sbjct: 304 DFFGVNHYTAFLVSATERKGPYPVPSLLDDVDTGSWADDSWLKSASAWLTLAPNSIHTAL 363 Query: 358 KYIKDTYNNPVIYITENGF--PQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYC 415 ++ + YN PV YITENG+ +S L D R +Y+R + + L + D +NL+ Y Sbjct: 364 THLNNLYNKPVFYITENGWSTDESRENSLIDDDRIQYYRASMESLLNCLD-DGINLKGYM 422 Query: 416 AWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 468 AWSL+DNFEW +GY RFGL+ VDF DPAR R P +A Y II++ ++ Sbjct: 423 AWSLMDNFEWMEGYIERFGLYEVDFSDPARTRTPRKAAFVYKHIIKHRVVDYE 475 >5JBO-A nrPDB Length = 485 Score = 573 bits (1477), Expect = e-164, Method: Composition-based stats. Identities = 177/483 (36%), Positives = 247/483 (51%), Gaps = 38/483 (7%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 ++ P F W ATAAYQ+EG G+GP +WDT+ H R GDVAC Y ++ Sbjct: 6 LSLPKDFEWGFATAAYQIEGAVKEGGRGPSIWDTYCHLEPSRT-NGANGDVACDHYHRYD 64 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLP-DGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 ED + + G YRFSLSWSR++P G IN++GI +Y+ +ID LLK GVTP VTLY Sbjct: 65 EDFDLLTKYGAKAYRFSLSWSRIIPLGGRLDPINEEGIQFYSNLIDALLKRGVTPWVTLY 124 Query: 120 HFDLPQTLEDQ-GGWLSEAIIE-SFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLG 177 H+DLPQ L D+ GGWL+ ++ F++YA+ CF FGDRVK WITINE + S+ Y G Sbjct: 125 HWDLPQALHDRYGGWLNVKEVQLDFERYARLCFERFGDRVKNWITINEPWIQSIYGYATG 184 Query: 178 MFPPGI---------PHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 PG T + A I +HAR+ Y FR QKG + +SL + Sbjct: 185 SNAPGRSSINKHSTEGDTTTEPWLAGKAQIMSHARAVAVYSKDFRASQKGQIGISLNGDY 244 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 EP D + D+EAA+R + FH+ +A PIF+ DYP ++ Q+ RLP Sbjct: 245 YEPWDSSDPRDKEAAERRMEFHIGWYANPIFLKKDYPASMRKQLG----------DRLPA 294 Query: 289 FTEEEKKMI-KGTADFFAVQYYTTRLIKYQENKKGELGIL-----QDAEIEFFPDPSWKN 342 T + ++ G DF+ + YYT++ ++ E + L + P Sbjct: 295 LTPADFAILNAGETDFYGMNYYTSQFARHYEGPVPKTDFLGAIHEHQENKDGSPVGEESG 354 Query: 343 VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFP------QSDPAPLDDTQRWEYFRQT 396 + W+ P K L + Y P IYITENG P + ++D R +YF Sbjct: 355 IFWLRSCPDMFRKHLARVHGLYGKP-IYITENGCPCPGEDKMTCEEAINDPFRIQYFDSH 413 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 + KAI D V ++ Y AW+LLDN EW+ GY RFG+ + D+ R P SA Sbjct: 414 LDSISKAISQDGVVVKGYFAWALLDNLEWSDGYGPRFGVTYTDY--TTLKRTPKKSALVL 471 Query: 457 AKI 459 + Sbjct: 472 KDM 474 >2E40-A nrPDB Length = 465 Score = 571 bits (1473), Expect = e-163, Method: Composition-based stats. Identities = 187/475 (39%), Positives = 271/475 (57%), Gaps = 31/475 (6%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 P F W ATAAYQ+EG D DG+ P +WDTF G ++ +GDVA SY W E Sbjct: 8 KLPKSFVWGYATAAYQIEGSPDKDGREPSIWDTFCKAPG-KIADGSSGDVATDSYNRWRE 66 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDG-TTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D++ +K G+ YRFSLSWSR++P G + +N GI +Y +I++L+K G+TP VTLYH Sbjct: 67 DVQLLKSYGVKAYRFSLSWSRIIPKGGRSDPVNGAGIKHYRTLIEELVKEGITPFVTLYH 126 Query: 121 FDLPQTLEDQ-GGWLS-EAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGM 178 +DLPQ L+D+ GGWL+ E I+ F YA+ CF +FGD V+ WIT NE V+SVM Y G+ Sbjct: 127 WDLPQALDDRYGGWLNKEEAIQDFTNYAKLCFESFGDLVQNWITFNEPWVISVMGYGNGI 186 Query: 179 FPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVS 238 F PG T + +H++I AHA + Y F++KQ G + ++L + WL P D ++ + Sbjct: 187 FAPGHVSN-TEPWIVSHHIILAHAHAVKLYRDEFKEKQGGQIGITLDSHWLIPYD-DTDA 244 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298 +EA RA+ F L FA PI+ G+YP +K + RLPEFT EE +++K Sbjct: 245 SKEATLRAMEFKLGRFANPIY-KGEYPPRIKKILG----------DRLPEFTPEEIELVK 293 Query: 299 GTADFFAVQYYTTRLIKYQENKKGELGILQDAE-IEFFPDPSWKNVDWIYVVPWGVCKLL 357 G++DFF + YTT L++ + + + + + ++ W+ G LL Sbjct: 294 GSSDFFGLNTYTTHLVQDGGSDELAGFVKTGHTRADGTQLGTQSDMGWLQTYGPGFRWLL 353 Query: 358 KYIKDTYNNPVIYITENGFPQSDPAPL------DDTQRWEYFRQTFQELFKAIQLDKVNL 411 Y+ Y+ P +Y+TENGFP L DDT R Y+R + L +A+ D ++ Sbjct: 354 NYLWKAYDKP-VYVTENGFPVKGENDLPVEQAVDDTDRQAYYRDYTEALLQAVTEDGADV 412 Query: 412 QVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSA----KEYAKIIRN 462 + Y WSLLDNFEW +GY RFG+ HVD+E + R P SA + + + I Sbjct: 413 RGYFGWSLLDNFEWAEGYKVRFGVTHVDYE--TQKRTPKKSAEFLSRWFKEHIEE 465 >1CBG-A nrPDB Length = 490 Score = 564 bits (1455), Expect = e-161, Method: Composition-based stats. Identities = 184/487 (37%), Positives = 267/487 (54%), Gaps = 40/487 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 F GF + A++A+Q EG DGKGP +WDTFTH+ E++ GDVA Y ++E Sbjct: 18 CFAPGFVFGTASSAFQYEGAAFEDGKGPSIWDTFTHKYPEKIKDRTNGDVAIDEYHRYKE 77 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 D+ +K + L YRFS+SW R+LP G +G +N++GI+YYN +I+++L NG+ P VTL+H Sbjct: 78 DIGIMKDMNLDAYRFSISWPRVLPKGKLSGGVNREGINYYNNLINEVLANGMQPYVTLFH 137 Query: 121 FDLPQTLEDQG-GWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 +D+PQ LED+ G+L I++ F YA+ CF FGDRVK WIT+NE +S+ +Y G F Sbjct: 138 WDVPQALEDEYRGFLGRNIVDDFRDYAELCFKEFGDRVKHWITLNEPWGVSMNAYAYGTF 197 Query: 180 PPGIP-----------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVW 228 PG G Y AAH + AHA + Y + ++ Q G++ ++L + W Sbjct: 198 APGRCSDWLKLNCTGGDSGREPYLAAHYQLLAHAAAARLYKTKYQASQNGIIGITLVSHW 257 Query: 229 LEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPE 288 EPA +D +AAKR + F L F P+ G YPE ++ + RLP+ Sbjct: 258 FEPASKE-KADVDAAKRGLDFMLGWFMHPL-TKGRYPESMRYLV----------RKRLPK 305 Query: 289 FTEEEKKMIKGTADFFAVQYYTTRL-IKYQENKKGELGILQDAEIEFF------PDPSWK 341 F+ EE K + G+ DF + YY++ K I D+ I P Sbjct: 306 FSTEESKELTGSFDFLGLNYYSSYYAAKAPRIPNARPAIQTDSLINATFEHNGKPLGPMA 365 Query: 342 NVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDP------APLDDTQRWEYFRQ 395 W+ + P G+ KLL Y+K+ YNNPVIYITENG + + L DT R +Y+ + Sbjct: 366 ASSWLCIYPQGIRKLLLYVKNHYNNPVIYITENGRNEFNDPTLSLQESLLDTPRIDYYYR 425 Query: 396 TFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 455 + AI D VN++ Y AWSL DN EW+ GY+ RFGL VDF++ + R P SA Sbjct: 426 HLYYVLTAI-GDGVNVKGYFAWSLFDNMEWDSGYTVRFGLVFVDFKNNLK-RHPKLSAHW 483 Query: 456 YAKIIRN 462 + ++ Sbjct: 484 FKSFLKK 490 >1E55-A nrPDB Length = 512 Score = 559 bits (1442), Expect = e-160, Method: Composition-based stats. Identities = 168/490 (34%), Positives = 258/490 (52%), Gaps = 48/490 (9%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP+ F + AAT+AYQ+EG W+ DGKG WD F H ER+ D+ SY +++ D Sbjct: 24 FPSDFTFGAATSAYQIEGAWNEDGKGESNWDHFCHNHPERILDGSNSDIGANSYHMYKTD 83 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGT-TGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 ++ +K++G+ YRFS+SW R+LP GT G IN GI YY +I+ LL+NG+ P VT++H+ Sbjct: 84 VRLLKEMGMDAYRFSISWPRILPKGTKEGGINPDGIKYYRNLINLLLENGIEPYVTIFHW 143 Query: 122 DLPQTLEDQ-GGWLS---EAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLG 177 D+PQ LE++ GG+L ++I+E + +A+ CF FGD+VK W+T N+ + SY G Sbjct: 144 DVPQALEEKYGGFLDKSHKSIVEDYTYFAKVCFDNFGDKVKNWLTFNDPQTFTSFSYGTG 203 Query: 178 MFPPGIPHFG-----------TGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226 +F PG G Y A HN++ AHA + Y+ +++ + L+ Sbjct: 204 VFAPGRCSPGLDCAYPTGNSLVEPYTAGHNILLAHAEAVDLYNKHYKRD-DTRIGLAFDV 262 Query: 227 VWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRL 286 + P S D++A +R+ +L F +P+ + GDYP ++S RL Sbjct: 263 MGRVPYG-TSFLDKQAEERSWDINLGWFLEPV-VRGDYPFSMRS----------LARERL 310 Query: 287 PEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQD---------AEIEFFPD 337 P F +E+K+ + G+ + + YYT+R K + +L + P Sbjct: 311 PFFKDEQKEKLAGSYNMLGLNYYTSRFSKNIDISPNYSPVLNTDDAYASQEVNGPDGKPI 370 Query: 338 PSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSD--------PAPLDDTQR 389 WIY+ P G+ LL +K+ Y NP IYITENG D A L+D +R Sbjct: 371 GPPMGNPWIYMYPEGLKDLLMIMKNKYGNPPIYITENGIGDVDTKETPLPMEAALNDYKR 430 Query: 390 WEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVP 449 +Y ++ L ++I L N+Q Y AWSLLDNFEW G++ R+G+ +VD + R Sbjct: 431 LDYIQRHIATLKESIDL-GSNVQGYFAWSLLDNFEWFAGFTERYGIVYVDRNNNC-TRYM 488 Query: 450 YTSAKEYAKI 459 SAK + Sbjct: 489 KESAKWLKEF 498 >5XGZ-A nrPDB Length = 457 Score = 559 bits (1440), Expect = e-159, Method: Composition-based stats. Identities = 155/470 (32%), Positives = 240/470 (51%), Gaps = 33/470 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W AT++YQ+EG +ADG+ P +WDTF + G + TG +A Y + ED Sbjct: 10 FPPDFQWGVATSSYQIEGAVEADGRSPSIWDTFCARPGA-IADGSTGAIANDHYHRYRED 68 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + +KQLG+ YRFS++W R+LPDG G +NQ G+D+Y +++D LL+ G+ P TLYH+D Sbjct: 69 IAIMKQLGVNAYRFSIAWPRILPDGR-GRVNQAGVDFYERLVDSLLEQGIEPYATLYHWD 127 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 +PQ D+ W ++++F +Y DRVK W+T+NE V+S + Y G PG Sbjct: 128 MPQVQHDRTPWYDRGVVDAFVEYTDVITRRLSDRVKYWMTLNEPWVISFLGYGAGEHAPG 187 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 + +AAH+++ AH ++ + + + L W+ A +S DQ A Sbjct: 188 LRD-KELYLRAAHHVLLAHGKAMPVIRANGNA--QTKAGIVLNLNWVNAAS-DSPEDQAA 243 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A+R F FA+P++ +G YPE + L + +I D Sbjct: 244 ARRYDQFFNRWFAEPLY-NGRYPEELLEWYGR----------DLVPVQPGDFDIITTPTD 292 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPS-WKNVDWIYVVPWGVCKLLKYIK 361 F AV YY +K +++F P + +DW V P G+ +L ++ Sbjct: 293 FLAVNYYARTTVKAGSTDPML-------QVDFVRPPGEYTAMDW-EVYPQGLYNILNWLH 344 Query: 362 DTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 Y P +Y+TENG D +DD QR Y F+ ++AIQ + L+ Y W Sbjct: 345 TDYAPPALYVTENGAAYDDQVSAAGEVDDPQRLAYLEGHFEAAYRAIQA-GIPLKGYFVW 403 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEA 467 SL+DNFEW +G+ RFG+ VD+ + R+ S K ++++ R NGL A Sbjct: 404 SLMDNFEWGRGFEKRFGIVFVDY--ATQQRIIKRSGKWFSQVTRANGLPA 451 >5AYI-A nrPDB Length = 457 Score = 553 bits (1426), Expect = e-158, Method: Composition-based stats. Identities = 159/464 (34%), Positives = 226/464 (48%), Gaps = 33/464 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FPA F W AATAAYQ+EG DG+G +WDTF+H G ++ TGDVAC SY + ED Sbjct: 6 FPADFVWGAATAAYQIEGAVREDGRGVSIWDTFSHTPG-KIADGTTGDVACDSYHRYGED 64 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + + LG+ YRFS++W R++P G G INQ G+D+Y++++D LL G+ P VTLYH+D Sbjct: 65 IGLLNALGMNAYRFSIAWPRIVPLG-AGPINQAGLDHYSRMVDALLGAGLQPFVTLYHWD 123 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ LED+ GW S A F +YA GDRV W T+NE +++ Y LG+ PG Sbjct: 124 LPQPLEDRLGWGSRATATVFAEYADIVVRQLGDRVTHWATLNEPWCSAMLGYYLGVHAPG 183 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 G +A+HNL+ H + + + Q + + L PA +S D A Sbjct: 184 HTDLKR-GLEASHNLLLGHGLAVQAMRA--AAPQPLQIGIVLQLTPTYPAS-DSPEDVAA 239 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A+R F F P+ G YP+ + + + P+ E+ I D Sbjct: 240 ARRFDGFVNRWFLDPLAGRG-YPQDMLDYYGAAA----------PQANPEDLTQIAAPLD 288 Query: 303 FFAVQYYTT-RLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIK 361 + V YY R + + + L D ++ D V P G+ +L + Sbjct: 289 WLGVNYYERMRAVDAPDASLPQAQRLDDPDLPHTADR--------EVYPEGLYDILLRLH 340 Query: 362 DTYNNPVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 + Y +YITENG D + D QR +F +L +A+ V L+ Y AW Sbjct: 341 NDYPFRPLYITENGCALHDEIAEDGGIHDGQRQAFFEAHLAQLQRALAA-GVPLKGYFAW 399 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 461 SLLDNFEW G S R+G+ + +FE R S I Sbjct: 400 SLLDNFEWAMGLSMRYGICYTNFE--TLERRIKDSGYWLRDFIA 441 >2Z1S-A nrPDB Length = 454 Score = 545 bits (1406), Expect = e-155, Method: Composition-based stats. Identities = 154/467 (32%), Positives = 237/467 (50%), Gaps = 30/467 (6%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FPA F W +T++YQ+EGG D G+ P +WDTF G +V GDVAC + ++ED Sbjct: 14 FPATFMWGTSTSSYQIEGGTDEGGRTPSIWDTFCQIPG-KVIGGDCGDVACDHFHHFKED 72 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +KQLG HYRFS++W R++P G IN++G+ +Y ++D++ G+ P++TLYH+D Sbjct: 73 VQLMKQLGFLHYRFSVAWPRIMP--AAGIINEEGLLFYEHLLDEIELAGLIPMLTLYHWD 130 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ +ED+GGW I+ F YA FG+R+ W TINE S++ Y G PG Sbjct: 131 LPQWIEDEGGWTQRETIQHFKTYASVIMDRFGERINWWNTINEPYCASILGYGTGEHAPG 190 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 ++ + AAH+++ H + + + K G + ++L ++ A D A Sbjct: 191 HENW-REAFTAAHHILMCHGIASNLHKE---KGLTGKIGITLNMEHVDAAS-ERPEDVAA 245 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 A R F FA+P+F +G YPE + G + L + ++I+ D Sbjct: 246 AIRRDGFINRWFAEPLF-NGKYPEDMVEW-------YGTYLNGLDFVQPGDMELIQQPGD 297 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKD 362 F + YYT +I+ N L + Q E D W + P KLL I+ Sbjct: 298 FLGINYYTRSIIR-STNDASLLQVEQVHMEEPVTDMGW------EIHPESFYKLLTRIEK 350 Query: 363 TYNN-PVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWS 418 ++ I ITENG D ++DT R Y + + + I+ L+ Y WS Sbjct: 351 DFSKGLPILITENGAAMRDELVNGQIEDTGRQRYIEEHLKACHRFIEEGG-QLKGYFVWS 409 Query: 419 LLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 LDNFEW GYS RFG+ H+++E + R P SA + +++ NG Sbjct: 410 FLDNFEWAWGYSKRFGIVHINYE--TQERTPKQSALWFKQMMAKNGF 454 >4JIE-A nrPDB Length = 503 Score = 545 bits (1405), Expect = e-155, Method: Composition-based stats. Identities = 188/481 (39%), Positives = 265/481 (55%), Gaps = 36/481 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 AFP GF + A +AYQVEG G+GP +WD F + G + N T DV Y ++E Sbjct: 37 AFPEGFVFGTAASAYQVEGMAKQGGRGPSIWDAFIEKPG-TIPNNATADVTVDEYHRYKE 95 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D+ +K +G YRFS+SWSR+ P+GT G +NQ+G+DYYN++ID ++K G+ P LYH+ Sbjct: 96 DVNIMKNMGFDAYRFSISWSRIFPNGT-GMVNQEGVDYYNRLIDYMVKKGIKPYANLYHY 154 Query: 122 DLPQTLEDQG-GWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP L +Q GWLS I+E+F YA FCF TFGDRVK W T NE ++ + YD G Sbjct: 155 DLPLALHEQYLGWLSPNIVEAFADYADFCFQTFGDRVKDWFTFNEPRCVAALGYDNGFHA 214 Query: 181 PGIP-------HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPAD 233 PG + T Y AAH+LI +HA + Y ++ QKG + + L VW EP Sbjct: 215 PGRCSGCDAGGNSTTEPYLAAHHLILSHAAAVKRYREKYQLYQKGRIGILLDFVWYEPFS 274 Query: 234 PNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEE 293 +S +D+ AA+RA FHL F PI I G YP + + R+P F++EE Sbjct: 275 -DSNADRAAAQRARDFHLGWFLDPI-IHGRYPYSMLEIVK----------DRMPTFSDEE 322 Query: 294 KKMIKGTADFFAVQYYTTRLIK-YQENKKGELGILQDAEIEF------FPDPSWKNVDWI 346 +M+K + D+ + +YT+ +K D + F P + N W+ Sbjct: 323 SRMVKDSIDYVGINHYTSFYMKDPGPWNLTPTSYQDDWHVGFAYERNGVPIGAQANSYWL 382 Query: 347 YVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPL----DDTQRWEYFRQTFQELFK 402 Y+VPWG+ K + Y+K+TY NP + ++ENG Q + DT R Y+R EL K Sbjct: 383 YIVPWGINKAVTYVKETYGNPTMILSENGMDQPGNVSITQGVHDTVRIRYYRNYITELKK 442 Query: 403 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 AI D + Y AWSLLDNFEW GY+SRFG+ +VD++ R P SA + ++ + Sbjct: 443 AID-DGAKVIGYFAWSLLDNFEWRLGYTSRFGIVYVDYK--TLKRYPKDSAFWFKNMLSS 499 Query: 463 N 463 Sbjct: 500 K 500 >3W53-A nrPDB Length = 506 Score = 544 bits (1401), Expect = e-155, Method: Composition-based stats. Identities = 150/480 (31%), Positives = 230/480 (47%), Gaps = 39/480 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 A+P F W +ATAA Q+EG + GK VWD F + G + + +VA Y + E Sbjct: 44 AWPKEFLWGSATAAAQIEGAGHSYGKEDSVWDAFARKEGA-IAGGENLEVAVDHYHRYRE 102 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 D++ +++LGL YRFS SW+R++P G T +N +G+D+Y++++D+LL+NG+ P +TLYH+ Sbjct: 103 DVQLMRELGLDSYRFSTSWARVVPGGRT--VNPEGLDFYSRLVDELLENGILPWLTLYHW 160 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 DLPQ LE++GGW + F +YA+ GDRVK W T NE S++ Y G P Sbjct: 161 DLPQALEERGGWTNRETSYKFLEYAETVHEKLGDRVKHWTTFNEPLCSSLIGYAAGEHAP 220 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G A H+ AH + L + + ++L P +P D E Sbjct: 221 GRQE-PQAALAAVHHQHLAHGLATARLRELGAEH----IGITLNLTNAVPNNPGDPVDLE 275 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 AA+R ++ P+ + G YPE + + + + + ++I Sbjct: 276 AARRVDALWNRMYLDPV-LRGSYPEDLLEDVQGLGLAEVIE--------AGDLEIISQPI 326 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIE-------------FFPDPSWKNVDWIYV 348 DF V +Y + G+ + + D + W V Sbjct: 327 DFLGVNHYHDDNVSGHPLPAGQPQPVVPTDSPKSSPFVGSEYVTFPARDLPRTAMGW-EV 385 Query: 349 VPWGVCKLLKYIKDTYNN-PVIYITENGFPQSDP----APLDDTQRWEYFRQTFQELFKA 403 P G+ LL + Y N P +YITENG +D ++D +R EY + +A Sbjct: 386 NPEGLRVLLNRLNQDYANLPSLYITENGASYTDTVTEAGTVEDPEREEYILNHLDAVVRA 445 Query: 404 IQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 I D V+++ Y WSLLDNFEW GY+ RFG+ HVD++ + R S K YA +I N Sbjct: 446 IA-DGVDVRGYFVWSLLDNFEWAWGYAKRFGIIHVDYQ--TQVRTIKNSGKAYAGLIAAN 502 >1GNX-A nrPDB Length = 479 Score = 540 bits (1393), Expect = e-154, Method: Composition-based stats. Identities = 156/481 (32%), Positives = 228/481 (47%), Gaps = 32/481 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP GF W +ATA+YQ+EG DG+ P +WDT+ G RV TGDVA Y W Sbjct: 16 LTFPEGFLWGSATASYQIEGAAAEDGRTPSIWDTYARTPG-RVRNGDTGDVATDHYHRWR 74 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED+ + +LGL YRFSL+W R+ P G G QKG+D+Y ++ D+LL G+ P+ TLYH Sbjct: 75 EDVALMAELGLGAYRFSLAWPRIQPTGR-GPALQKGLDFYRRLADELLAKGIQPVATLYH 133 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLPQ LE+ GGW A E F +YA GDRVK W T+NE + + Y G+ Sbjct: 134 WDLPQELENAGGWPERATAERFAEYAAIAADALGDRVKTWTTLNEPWCSAFLGYGSGVHA 193 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG +AAH+L H + + S++L + P +S +D Sbjct: 194 PGRTD-PVAALRAAHHLNLGHGLAVQALRDRLPA--DAQCSVTLNIHHVRPLT-DSDADA 249 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 +A +R +F P+ + G YPE + A ++ + + ++ Sbjct: 250 DAVRRIDALANRVFTGPM-LQGAYPEDLVKDTAGLTDWS--------FVRDGDLRLAHQK 300 Query: 301 ADFFAVQYYTTRLIKYQENK----------KGELGILQDAEIEFFPDPSWKNVDWIYVVP 350 DF V YY+ L+ + + F P V P Sbjct: 301 LDFLGVNYYSPTLVSEADGSGTHNSDGHGRSAHSPWPGADRVAFHQPPGETTAMGWAVDP 360 Query: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQL 406 G+ +LL+ + + + ITENG D ++D +R Y R + +AI+ Sbjct: 361 SGLYELLRRLSSDFPALPLVITENGAAFHDYADPEGNVNDPERIAYVRDHLAAVHRAIK- 419 Query: 407 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 D +++ Y WSLLDNFEW GYS RFG +VD+ P R+P SA+ YA++ R L Sbjct: 420 DGSDVRGYFLWSLLDNFEWAHGYSKRFGAVYVDY--PTGTRIPKASARWYAEVARTGVLP 477 Query: 467 A 467 Sbjct: 478 T 478 >5GNX-A nrPDB Length = 467 Score = 538 bits (1387), Expect = e-153, Method: Composition-based stats. Identities = 159/468 (33%), Positives = 231/468 (49%), Gaps = 34/468 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W AATAAYQ+EG ADG G +WD F+H G TGDVAC Y W ED Sbjct: 14 FPEGFLWGAATAAYQIEGSSMADGAGESIWDRFSHTPGNM-KDGDTGDVACDHYNRWRED 72 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 ++ +K+L L YRFS+SWSR++P G G IN KG+ +Y++++D LL+ G+ P+ TLYH+D Sbjct: 73 IELMKRLNLQAYRFSVSWSRVIPQGR-GAINPKGLAFYDRLVDGLLEAGIEPLATLYHWD 131 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LP L+D+GGWL+ I + F Y Q F F RVK W TIN+ V+ Y G PG Sbjct: 132 LPAALDDRGGWLNPDIADWFADYGQVLFEKFKGRVKTWGTINQPWVIVDGGYLHGALAPG 191 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 A HN+++AH + FR+ +G + + L PA + D+ A Sbjct: 192 HRS-AYEAVIAGHNVLRAHGAAVR----RFREVGEGQIGIVLNIEPKYPAS-DKPEDEAA 245 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 +RA F P+ G YPE + + + EF +E+ ++I D Sbjct: 246 RRRAEAQMNRWFLDPLMGRG-YPEELTDVYGAAWR----------EFPKEDFELIAEPTD 294 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKD 362 + + +YT + + + + + W V P + L ++ + Sbjct: 295 WMGLNWYTRAVPENAPDA-----WPTRSRPVRQTQHAHTETGW-EVYPPALTDTLVWLSE 348 Query: 363 TY-NNPVIYITENGFPQSDP-----APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCA 416 + +TENG DP + D R Y + + L AI V+L+ Y A Sbjct: 349 QTGGKLPLMVTENGSAWYDPPHAIDGRIHDPMRVHYLQTHIKALHDAI-GKGVDLRGYMA 407 Query: 417 WSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464 WSLLDN EW+ GYS RFG+ HV+F + R S YA++I+ +G Sbjct: 408 WSLLDNLEWSLGYSKRFGIVHVNF--ATQERTIKDSGLLYAEVIKTHG 453 >5DT5-A nrPDB Length = 471 Score = 534 bits (1375), Expect = e-152, Method: Composition-based stats. Identities = 142/466 (30%), Positives = 226/466 (48%), Gaps = 29/466 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 M F F + AT++YQ+EG D G+ P +WDTF G +VF+ GDVAC Y +E Sbjct: 24 MKFAPNFVFGTATSSYQIEGAHDEGGRTPSIWDTFCDTDG-KVFEKHNGDVACDHYHRFE 82 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ IKQLG+ YRFS++W R+ P + G N +G+ +Y + L + G+ P VTLYH Sbjct: 83 EDIQHIKQLGVDTYRFSIAWPRIFP--SKGQFNPEGMAFYKTLATRLQEEGIKPAVTLYH 140 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLP ++GGW++ ++ F +A+ CF V WIT NE +SY LG Sbjct: 141 WDLPMWAHEEGGWVNRDSVDWFLDFARVCFEELDGIVDSWITHNEPWCAGFLSYHLGQHA 200 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG +A H+++ +H ++ F ++L+L + A +S++DQ Sbjct: 201 PGHTDMN-EAVRAVHHMLLSHGKAVEMLKGEFNSATPIGITLNLAPKY---AKTDSINDQ 256 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 A A + F PIF G YP + + + + + + I Sbjct: 257 IAMNNADGYANRWFLDPIF-KGQYPVDMMNLFSKYVHTYDFIHA-------GDLATISTP 308 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 DFF + +Y+ L+++ + + D + W + P L++ + Sbjct: 309 CDFFGINFYSRNLVEFSAASDFL-------HKDAYSDYDKTGMGWD-IAPSEFKDLIRRL 360 Query: 361 KDTYNNPVIYITENGFPQSD---PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAW 417 + Y + IYITENG D + D R +Y Q Q + + + +N+ Y W Sbjct: 361 RAEYTDLPIYITENGAAFDDQLVDGKIHDQNRIDYVAQHLQAVSD-LNDEGMNIAGYYLW 419 Query: 418 SLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 SLLDNFEW+ GY RFG+ +VDF+ + R+ SA YA +I+ + Sbjct: 420 SLLDNFEWSFGYDKRFGIIYVDFD--TQERIWKDSAHWYANVIQTH 463 >5NS7-A nrPDB Length = 454 Score = 530 bits (1367), Expect = e-151, Method: Composition-based stats. Identities = 146/461 (31%), Positives = 226/461 (49%), Gaps = 31/461 (6%) Query: 5 AGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLK 64 F W +T++YQ+EG + G+GP +WDTF+ G V GDVAC Y + EDL Sbjct: 21 DMFTWGVSTSSYQIEGAANQGGRGPSIWDTFSKIPGA-VANGDNGDVACDHYHRYNEDLD 79 Query: 65 CIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLP 124 +K LG+ YRFS++W R++P G G +N++G+D+Y+++ID L+ G+TP TLYH+DLP Sbjct: 80 LMKWLGVGAYRFSIAWPRVIPSGY-GALNKEGMDFYDRLIDGALERGITPWPTLYHWDLP 138 Query: 125 QTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIP 184 Q+L+D+GGW + F +Y+Q F DR+K WITINE + + + G+ PGI Sbjct: 139 QSLQDKGGWNNRDCAYWFAEYSQKMAEAFSDRLKNWITINEPFCSAWLGHLYGVMAPGIK 198 Query: 185 HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAK 244 T G A+H+L+ H + + + + V ++L S D+ A + Sbjct: 199 DLKT-GINASHHLLLGHGLATKAIREVSSEL---KVGITLNFTPAITLG-ESSEDKLAVE 253 Query: 245 RAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFF 304 A F F P+F YPE + + ++I D+ Sbjct: 254 LADGFDNRWFGDPVF-KAKYPEDIVKAFGKEVP-----------IHPGDMEIISTPLDYL 301 Query: 305 AVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTY 364 + YY + ++Y K + P+ + W V +LL+ + Y Sbjct: 302 GLNYYFRQTVEYDATAKPL-----PYKQVTAPNVERTGMGW-EVHAQSFTELLERVSKEY 355 Query: 365 NNPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLD 421 I+ITENG D +DD R Y + +F A + V + Y AWSL+D Sbjct: 356 KPKEIFITENGSAWDDEVVDGKVDDPNRVSYLERHLDAMFAA-KNKGVPISGYFAWSLID 414 Query: 422 NFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 NFEW GY+ RFG+ +VD++ + R+P +SA Y K I+ Sbjct: 415 NFEWAYGYAKRFGIIYVDYQ--TQKRIPKSSAYYYQKRIKE 453 >5YHS-A nrPDB Length = 475 Score = 525 bits (1352), Expect = e-149, Method: Composition-based stats. Identities = 161/486 (33%), Positives = 248/486 (51%), Gaps = 38/486 (7%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 M FP F + AA+A+YQVEG W+ DGKG WD F+ G + + GD+A Y ++ Sbjct: 1 MKFPHDFLFGAASASYQVEGAWNEDGKGVTNWDEFSKIPG-KTYNGTNGDIAVDHYHRYK 59 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 ED++ + ++GL YRFS+SW+R+LP G G +N+KGI++YN +ID+ LK G+ P VTLYH Sbjct: 60 EDVRLMAEMGLESYRFSISWARILPTGD-GKVNEKGIEFYNNLIDECLKYGIVPFVTLYH 118 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 +DLP LE GGW ++ E+F KYA+ CF FGDRVK WIT NE + + Y G P Sbjct: 119 WDLPLPLEKDGGWTNKRTAEAFVKYAETCFKAFGDRVKHWITFNETVMFCGLGYLKGAHP 178 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PGI + +QA H + AHA++ Y L + G + ++ + D + + Sbjct: 179 PGIQNDVPKYFQATHYVFYAHAKTVAVYKQLKQY---GEIGITHVFLPAYSVD-DQKENI 234 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 +AA A + + PI + G+YP V Q+ P +T EE ++IK Sbjct: 235 QAANHANEYETYWYYDPI-LKGEYPSYVVQQLKEKGW--------TPNWTVEELEIIKQN 285 Query: 301 A---DFFAVQYYTT-RLIKYQENKKGELGILQDAEIEF-------------FPDPSWKNV 343 A DF + YY R+ +Y + K E +++ + D ++ Sbjct: 286 AEENDFIGLNYYQPIRVERYDMDIKSEEHSRENSTLAPGNPSFDGFYRTVKMDDKTYTKW 345 Query: 344 DWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQEL 400 W + P G + L +K Y + +Y+TENG DP + D R ++ + + Sbjct: 346 GW-EISPEGFLEGLHMLKARYGDIKMYVTENGLGDEDPIIDGEIVDVPRIKFIEAHLKVM 404 Query: 401 FKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKII 460 +AI+ + +NL+ Y AWS++D W GY ++G VD D + R S Y +++ Sbjct: 405 KRAIE-EGINLKGYYAWSVIDLLSWLNGYKKQYGFIFVDHNDNLK-RKKKLSFHWYKRVV 462 Query: 461 RNNGLE 466 G E Sbjct: 463 ETRGEE 468 >5VAQ-A nrPDB Length = 954 Score = 522 bits (1346), Expect = e-148, Method: Composition-based stats. Identities = 174/465 (37%), Positives = 249/465 (53%), Gaps = 37/465 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F W T A QVEG W DGKGP +WD F H + V + + + SY E+ Sbjct: 51 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYIFLEK 107 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL + +G++ Y+FS+SW RL PDG N KG+ YY+ ++D L+ + PIVTLYH+ Sbjct: 108 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 167 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP L+++ GGW ++ II+ F+ YA +CF FGDRVK WITI+ +++ Y GM Sbjct: 168 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 227 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG Y HNLIKAH++ WH+Y++ FR QKG +S++L + W+EP + D Sbjct: 228 PGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPQRSENTMDI 287 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 ++++ L FA PI DGDYPE ++ ++ S+ LP F+E EK ++GT Sbjct: 288 FKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGT 337 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADFFA + K + + + + L +I Sbjct: 338 ADFFAFSFGPNNFKPLNTMAKMGQNVSLN-----------------------LREALNWI 374 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 K YNNP I I ENG+ +DT + ++ +AI+LD++ + Y AWSLL Sbjct: 375 KLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLL 434 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 D FEW Y+ R GLF+VDF + R P +SA Y +IIR NG Sbjct: 435 DGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGF 479 Score = 311 bits (798), Expect = 3e-85, Method: Composition-based stats. Identities = 150/414 (36%), Positives = 223/414 (53%), Gaps = 31/414 (7%) Query: 60 EEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 ++ L+ + ++ +THYRF+L W+ +LP G +N++ + YY ++ + LK G++ +VTLY Sbjct: 554 KKQLEMLARMKVTHYRFALDWASVLPTGQLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 613 Query: 120 -----HFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174 H LP+ L GWL+ + E+F YA CF GD VK WITINE N LS + Sbjct: 614 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI-- 671 Query: 175 DLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADP 234 G Y AAHNL+ AHA +W YD FR Q+G VSLSL A W EPA+P Sbjct: 672 --------YNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANP 723 Query: 235 NSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294 + S AA+R + F + FA+P+F GDYP ++ IAS ++G SS LP TE E+ Sbjct: 724 YADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASK-HRRGLSSSALPRLTEAER 782 Query: 295 KMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVC 354 +++KGT DF A+ ++TTR + +++ +D + + + V+PWGV Sbjct: 783 RLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQF-LQDITRLSSPTRLAVIPWGVR 841 Query: 355 KLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVY 414 KLL++++ Y + IYIT +G D A DD R Y + QE+ KA +DKV ++ Y Sbjct: 842 KLLRWVRRNYGDMDIYITASGI--DDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGY 899 Query: 415 CAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 468 A+ L + RFG F DF+ +S + Y K+I + G Sbjct: 900 YAFKLAEEKS-----KPRFGFFTSDFKA-------KSSIQFYNKVISSRGFPFE 941 >4ZEN-A nrPDB Length = 485 Score = 520 bits (1341), Expect = e-148, Method: Composition-based stats. Identities = 165/487 (33%), Positives = 244/487 (50%), Gaps = 41/487 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W AA+AAYQVEG W+ DGKG VWD F Q G R FK GDVA Y ++ED Sbjct: 16 FPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPG-RTFKGTNGDVAVDHYHRYQED 74 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + + ++GL YRFS+SWSR+ PDG G +N+KG+D+Y+++I++L +G+ PIVTLYH+D Sbjct: 75 VALMAEMGLKAYRFSVSWSRVFPDGN-GAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWD 133 Query: 123 LPQTLED-QGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 +PQ L D G W S II+ FD+YA F FGDRVK W+T+NE N+ Y LG+ PP Sbjct: 134 VPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISFGYRLGLHPP 193 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 G+ Y+A H A+A+ S+ G + S + P D + Sbjct: 194 GVKDMKR-MYEANHIANLANAKVIQSFRHYVP---DGKIGPSFAYSPMYPYDSR-PENVL 248 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMI-KGT 300 A + A F + ++ G YP+ + + S + P + +++ Sbjct: 249 AFENAEEFQNHWWMD-VYAWGMYPQAAWNYLESQGLE--------PTVAPGDWELLQAAK 299 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAE-------------IEFFPDPSWKNVDWIY 347 DF V YY T +++ G++ + +P +W + Sbjct: 300 PDFMGVNYYQTTTVEHNPPDGVGEGVMNTTGKKGTSTSSGIPGLFKTVRNPHVDTTNWDW 359 Query: 348 -VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAP----LDDTQRWEYFRQTFQELFK 402 + P G+ L+ I + Y P I ITENG + D ++D R +Y R+ QE+ + Sbjct: 360 AIDPVGLRIGLRRIANRYQLP-ILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQR 418 Query: 403 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP---RVPYTSAKEYAKI 459 AI D V++ YCAWS D W GY R+G +V+ +D + R+ S Y ++ Sbjct: 419 AIT-DGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRV 477 Query: 460 IRNNGLE 466 I NG E Sbjct: 478 IETNGAE 484 >5WKA-A nrPDB Length = 473 Score = 511 bits (1316), Expect = e-145, Method: Composition-based stats. Identities = 151/483 (31%), Positives = 214/483 (44%), Gaps = 38/483 (7%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP GF W +TAAYQ+EG DG+ P +WDTF+ G +V TGDVAC Y WEED Sbjct: 2 FPDGFVWGTSTAAYQIEGAVAEDGRTPSIWDTFSRTKG-KVVNGDTGDVACDHYHRWEED 60 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 L + +LG+ YRFS++W R+ PD TG NQKG+D+Y ++ID L + P+ T+YH+D Sbjct: 61 LDLLAELGVQAYRFSVAWPRIHPD-VTGPANQKGLDFYQRLIDGLRDRNIIPLPTMYHWD 119 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182 LPQ LED+GGW+ F YA D + +W T NE + + Y G PG Sbjct: 120 LPQALEDEGGWIVRDTALRFADYAATVLEKL-DGIDKWTTFNEPWTSAWLGYGYGHHAPG 178 Query: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242 G H L+ + ++ + + L+L L P D EA Sbjct: 179 RTDIGAAAAATHHLLLAH-GLGVQAARAIRPHVE---IGLTLNLGVLRPGTTEDQ-DVEA 233 Query: 243 AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302 RA ++ P+F G+YP + + + ++I D Sbjct: 234 TWRADGNQNRIWLDPLF-KGEYPADMIE-------HYSRWTPGFHTVQNGDLEIISSPID 285 Query: 303 FFAVQYYTTRLIKYQENKKGELGILQDAEIEF--------------FPDPSWKNVDWIYV 348 F V +Y + + + P + W V Sbjct: 286 FLGVNFYGPGTVMNVGREDAARAAGFNVGPRPESDEDNHLRCIGVETPGRPKTAMGW-EV 344 Query: 349 VPWGVCKLLKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAI 404 + +LL IK+ Y + +YITENG D + D +R Y + AI Sbjct: 345 DATALRELLVRIKNEYTDIPLYITENGAAYHDYVNASGDVKDPERITYLNDHLEACLGAI 404 Query: 405 QLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464 D VNLQ Y WSLLDNFEW GYS RFG+ +D++ R+P S + Y ++ NG Sbjct: 405 D-DGVNLQGYFIWSLLDNFEWGFGYSRRFGIVWIDYD--TGRRIPKASYRWYQGVVATNG 461 Query: 465 LEA 467 L Sbjct: 462 LPD 464 >5WI9-A nrPDB Length = 470 Score = 510 bits (1315), Expect = e-145, Method: Composition-based stats. Identities = 175/466 (37%), Positives = 250/466 (53%), Gaps = 37/466 (7%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 FP F W T A QVEG W DGKGP +WD F H + V + + + SY E+ Sbjct: 29 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYIFLEK 85 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL + +G++ Y+FS+SW RL PDG N KG+ YY+ ++D L+ + PIVTLYH+ Sbjct: 86 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 145 Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 DLP L+++ GGW ++ II+ F+ YA +CF FGDRVK WITI+ +++ Y GM Sbjct: 146 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 205 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 PG Y HNLIKAH++ WH+Y++ FR QKG +S++L + W+EP + D Sbjct: 206 PGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDI 265 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 ++++ L FA PI DGDYPE ++ ++ S+ LP F+E EK ++GT Sbjct: 266 FKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGT 315 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADFFA + K + + + + L +I Sbjct: 316 ADFFAFSFGPNNFKPLNTMAKMGQNVSLN-----------------------LREALNWI 352 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 K YNNP I I ENG+ +DT + ++ +AI+LD++ + Y AWSLL Sbjct: 353 KLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLL 412 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466 D FEW Y+ R GLF+VDF + R P +SA Y +IIR NG E Sbjct: 413 DGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFE 458 >5W21-A nrPDB Length = 981 Score = 507 bits (1305), Expect = e-144, Method: Composition-based stats. Identities = 196/481 (40%), Positives = 273/481 (56%), Gaps = 49/481 (10%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKN--------------- 46 FP GF WA +AAYQ EGGW GKG +WDTFTH + Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119 Query: 47 QTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDD 106 TGDVA SY D + +++LG+THYRFS+SW+R+LP+G+ G N++G+ YY ++++ Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179 Query: 107 LLKNGVTPIVTLYHFDLPQTLED-QGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165 L + GV P+VTLYH+DLPQ L+D GGW + A+ + F YA+ CF FG +VK WITI+ Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239 Query: 166 ANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLF 225 V++ Y G PGI GY AHNL+ AHA+ WH Y++ FR Q G VS++L Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALS 299 Query: 226 AVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSR 285 + W+ P S +E ++++ F L FAKP+FIDGDYPE +K+ ++S+ Sbjct: 300 SHWINPRRMTDHSIKE-CQKSLDFVLGWFAKPVFIDGDYPESMKNNLSSI---------- 348 Query: 286 LPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDW 345 LP+FTE EKK IKGTADFFA+ + L D ++F S Sbjct: 349 LPDFTESEKKFIKGTADFFALCF-----------GPTLSFQLLDPHMKFRQLESPN---- 393 Query: 346 IYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQ 405 + +LL +I +N+P I+I ENG+ S DD + Y ++ E KAI+ Sbjct: 394 -------LRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIK 446 Query: 406 LDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 LD V++ Y AWSL+D FEW++GYS R GLF+VDF + +P +SA Y K+I NG Sbjct: 447 LDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGF 506 Query: 466 E 466 Sbjct: 507 P 507 Score = 315 bits (809), Expect = 2e-86, Method: Composition-based stats. Identities = 153/482 (31%), Positives = 226/482 (46%), Gaps = 60/482 (12%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGK-GPCVWDTFTHQGGERVFKNQTG-------DVAC 53 FP F W QV+ +WD + +V T D A Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577 Query: 54 GSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVT 113 + + ++++ +TH+RFSL W+ +LP G +N + YY + +L++ +T Sbjct: 578 -----IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNIT 632 Query: 114 PIVTLYHFD-------LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEA 166 P+V L + LP+ L QG W + +F +YA+ CF G VK WIT+NE Sbjct: 633 PVVAL--WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690 Query: 167 NVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226 ++ Y A HNL+KAHA +WH Y+ FR Q G +S++L A Sbjct: 691 YTRNM------------------TYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQA 732 Query: 227 VWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRL 286 W+EPA P S D+E A+R + F + A+PIF GDYP V++ + + + L Sbjct: 733 DWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRN------NFLL 786 Query: 287 PEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD-W 345 P FTE+EKK+I+GT DF A+ +YTT L+ K+ + E++ D +W N Sbjct: 787 PYFTEDEKKLIQGTFDFLALSHYTTILV--DSEKEDPIKYNDYLEVQEMTDITWLNSPSQ 844 Query: 346 IYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQ 405 + VVPWG+ K+L ++K Y + +YI NG A DD R Y + E KA Sbjct: 845 VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAE-DDQLRVYYMQNYINEALKAHI 903 Query: 406 LDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 LD +NL Y A+S D + RFGL+ + P S K Y KII +NG Sbjct: 904 LDGINLCGYFAYSFNDRT------APRFGLYR--YAADQFE--PKASMKHYRKIIDSNGF 953 Query: 466 EA 467 Sbjct: 954 PG 955 >3ZJK-A nrPDB Length = 431 Score = 503 bits (1295), Expect = e-143, Method: Composition-based stats. Identities = 143/462 (30%), Positives = 219/462 (47%), Gaps = 43/462 (9%) Query: 5 AGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLK 64 F W AT+AYQ+EG DG+GP +WD F + G + TG+ AC Y +EED+ Sbjct: 6 EKFLWGVATSAYQIEGATQEDGRGPSIWDAFAQRPGA-IRDGSTGEPACDHYRRYEEDIA 64 Query: 65 CIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLP 124 ++ LG+ YRFS++W R+LP+G G IN KG+ +Y++++D LL +G+TP +TLYH+DLP Sbjct: 65 LMQSLGVRAYRFSVAWPRILPEGR-GRINPKGLAFYDRLVDRLLASGITPFLTLYHWDLP 123 Query: 125 QTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIP 184 LE++GGW S +F +YA+ DRV + T+NE + + + G PG+ Sbjct: 124 LALEERGGWRSRETAFAFAEYAEAVARALADRVPFFATLNEPWCSAFLGHWTGEHAPGLR 183 Query: 185 HFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAK 244 + +AAH+L+ H + + + + V + L P D EA Sbjct: 184 NL-EAALRAAHHLLLGHGLAVEALRAAGAR----RVGIVLN------FAPAYGEDPEAVD 232 Query: 245 RAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFF 304 A +H F PI G YPE + + +++ DF Sbjct: 233 VADRYHNRFFLDPILGKG-YPES------------PFRDPPPVPILSRDLELVARPLDFL 279 Query: 305 AVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTY 364 V YY + + + P V P G+ LLK + Sbjct: 280 GVNYYAPVRVAPGTGTLP---------VRYLPPEGPATAMGWEVYPEGLHHLLKRLGREV 330 Query: 365 NNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 P +Y+TENG D A ++D +R Y + +A + + V+L+ Y WSL+ Sbjct: 331 PWP-LYVTENGAAYPDLWTGEAVVEDPERVAYLEAHVEAALRA-REEGVDLRGYFVWSLM 388 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 462 DNFEW GY+ R GL++VDF P++ R+P SA Y + I Sbjct: 389 DNFEWAFGYTRRSGLYYVDF--PSQRRIPKRSALWYRERIAR 428 >1W9D-M nrPDB Length = 501 Score = 488 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 153/485 (31%), Positives = 237/485 (48%), Gaps = 49/485 (10%) Query: 10 AAATAAYQVEGGWDADGKGPCVWDTFTHQGGERV-FKNQTGDVACGSYTLWEEDLKCIKQ 68 A++AYQ+EG G+G +WD FTH+ + + GD C S++ W++D+ + + Sbjct: 32 GVASSAYQIEGTI---GRGLNIWDGFTHRYPNKSGPDHGNGDTTCDSFSYWQKDIDVLDE 88 Query: 69 LGLTHYRFSLSWSRLLPDG-TTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTL 127 L T YRFS++WSR++P G + +N+KGIDYY+ +I L+K G+TP VTL+H+DLPQTL Sbjct: 89 LNATGYRFSIAWSRIIPRGKRSRGVNEKGIDYYHGLISGLIKKGITPFVTLFHWDLPQTL 148 Query: 128 EDQG-GWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHF 186 +D+ G+L II+ F YA CF FGD VK W+TIN+ + Y + PG Sbjct: 149 QDEYEGFLDPQIIDDFKDYADLCFEEFGDSVKYWLTINQLYSVPTRGYGSALDAPGRCSP 208 Query: 187 G-----------TGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPN 235 T Y AH+ + AHA+ Y + Q G + ++ W P + Sbjct: 209 TVDPSCYAGNSSTEPYIVAHHQLLAHAKVVDLYRKNYT-HQGGKIGPTMITRWFLPYNDT 267 Query: 236 SVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKK 295 A +R F L F P+ +G YP+++ + RLP F+ EE Sbjct: 268 DRHSIAATERMKEFFLGWFMGPL-TNGTYPQIMIDTVG----------ERLPSFSPEESN 316 Query: 296 MIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIE---------------FFPDPSW 340 ++KG+ DF + YY T+ + N + F Sbjct: 317 LVKGSYDFLGLNYYFTQYAQPSPNPVNSTNHTAMMDAGAKLTYINASGHYIGPLFEKDKA 376 Query: 341 KNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFP----QSDPAPLDDTQRWEYFRQT 396 + D IY P G+ ++ Y K+ Y NP+IY+TENG ++ + D R +Y Sbjct: 377 DSTDNIYYYPKGIYSVMDYFKNKYYNPLIYVTENGISTPGDENRNQSMLDYTRIDYLCSH 436 Query: 397 FQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEY 456 L K I+ VN++ Y AW+L DN+E+N+G++ RFGL ++D+ + R S + Y Sbjct: 437 LCFLNKVIKEKDVNVKGYLAWALGDNYEFNKGFTVRFGLSYIDWNNVT-DRDLKKSGQWY 495 Query: 457 AKIIR 461 I Sbjct: 496 QSFIS 500 >1PBG-A nrPDB Length = 468 Score = 475 bits (1223), Expect = e-134, Method: Composition-based stats. Identities = 147/481 (30%), Positives = 219/481 (45%), Gaps = 32/481 (6%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEE 61 P F + ATAAYQ EG DGKGP WD + T + A Y + Sbjct: 4 TLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDN-----YWYTAEPASDFYHKYPV 58 Query: 62 DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121 DL+ ++ G+ R S++WSR+ P G G +N+KG+++Y+K+ + K V P VTL+HF Sbjct: 59 DLELAEEYGVNGIRISIAWSRIFPTGY-GEVNEKGVEFYHKLFAECHKRHVEPFVTLHHF 117 Query: 122 DLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPP 181 D P+ L G +L+ IE F YA FCF F + V W T NE + Y +G FPP Sbjct: 118 DTPEALHSNGDFLNRENIEHFIDYAAFCFEEFPE-VNYWTTFNEIGPIGDGQYLVGKFPP 176 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 GI + +Q+ HN++ +HAR+ Y K KG + + P DP + +D Sbjct: 177 GIKYDLAKVFQSHHNMMVSHARAVKLYKD---KGYKGEIGVVHALPTKYPYDPENPADVR 233 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIAS-MSQKQGYPSSRLPEFTEEEKKMIKGT 300 AA+ H ++ G Y + + +++ G R +F + K Sbjct: 234 AAELEDIIHNKFILDATYL-GHYSDKTMEGVNHILAENGGELDLRDEDFQALDAA--KDL 290 Query: 301 ADFFAVQYYTT----------RLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIY-VV 349 DF + YY + +I + +KG DW + + Sbjct: 291 NDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRVAPDYVPRTDWDWIIY 350 Query: 350 PWGVCKLLKYIKDTY-NNPVIYITENGFPQSDP---APLDDTQRWEYFRQTFQELFKAIQ 405 P G+ + +K+ Y N IYITENG D + D R +Y +Q + L AI Sbjct: 351 PEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKQHLEVLSDAIA 410 Query: 406 LDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 D N++ Y WSL+D F W+ GY R+GLF+VDF+ + R P SA Y K+ + Sbjct: 411 -DGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFD--TQERYPKKSAHWYKKLAETQVI 467 Query: 466 E 466 E Sbjct: 468 E 468 >2XHY-A nrPDB Length = 479 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 128/490 (26%), Positives = 217/490 (44%), Gaps = 45/490 (9%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV--------- 51 + P F W A AA+QVEGGW+ GKGP + D T G V + T +V Sbjct: 6 LTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLT-GGAHGVPREITKEVLPGKYYPNH 64 Query: 52 -ACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110 A Y ++ED+K ++G +R S++W+R+ P G N++G+ +Y+ + D+LLK Sbjct: 65 EAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDELLKY 124 Query: 111 GVTPIVTLYHFDLPQTL-EDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVL 169 + P++TL HF++P L + G W + +++ F ++A+ F + +VK W+T NE N Sbjct: 125 NIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNEINNQ 184 Query: 170 S-VMSYDLGMFPPG-----IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223 + G G + YQ H+ A A + + + + + G + L+ Sbjct: 185 RNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFVASALAVKAARRINPEMKVGCM-LA 243 Query: 224 LFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPS 283 + ++ +P+ V + + R D + + G YP V ++ Sbjct: 244 MVPLYPYSCNPDDVMFAQESMRERYVFTD-----VQLRGYYPSYVLNEWERRGFNIKMED 298 Query: 284 SRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNV 343 L E GT D+ YY T +K + + + + P+P K Sbjct: 299 GDLDVLRE-------GTCDYLGFSYYMTNAVKAEGGTGDAISGFEGS----VPNPYVKAS 347 Query: 344 DWIYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQ 398 DW + + P G+ L + + Y P ++I ENGF D ++D R +Y R + Sbjct: 348 DWGWQIDPVGLRYALCELYERYQRP-LFIVENGFGAYDKVEEDGSINDDYRIDYLRAHIE 406 Query: 399 ELFKAIQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPAR---PRVPYTSAK 454 E+ KA+ D V+L Y W +D + G YS R+G +V+ D R S Sbjct: 407 EMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFN 466 Query: 455 EYAKIIRNNG 464 Y ++I +NG Sbjct: 467 WYKEVIASNG 476 >4F66-A nrPDB Length = 480 Score = 467 bits (1202), Expect = e-132, Method: Composition-based stats. Identities = 133/489 (27%), Positives = 218/489 (44%), Gaps = 43/489 (8%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV---------A 52 P F W A AA+Q+EGGW GKG V D T + G + A Sbjct: 6 KLPENFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVAREITAGVLEGKYYPNHEA 65 Query: 53 CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112 Y ++ED+K ++G +R S++W+R+ P G N+ G+ +Y+ + D+ LK G+ Sbjct: 66 IDFYHHYKEDVKLFAEMGFKCFRTSIAWTRIFPKGDEAEPNEAGLQFYDDLFDECLKYGI 125 Query: 113 TPIVTLYHFDLPQTLE-DQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSV 171 P+VTL HF+LP L + GG+ + +I+ F +A+ CF + D+VK W+T NE N + Sbjct: 126 EPVVTLSHFELPYHLVTEYGGFTNRKVIDFFVHFAEVCFRRYKDKVKYWMTFNEINNQAN 185 Query: 172 MSYDLGMFPPGIPHFGTGG------YQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLF 225 D F + G YQAAH + A AR+ ++ G + +++ Sbjct: 186 YQEDFAPFTNSGIVYKEGDDREAIMYQAAHYELVASARAVKIGHAINPNLNIGCM-VAMC 244 Query: 226 AVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSR 285 ++ +P + + A + + + + G YPE + + K Sbjct: 245 PIYPATCNPKDILMAQKAMQK-----RYYFADVHVHGFYPEHIFKYWERKAIKV------ 293 Query: 286 LPEFTEEEKKMI-KGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD 344 +FTE +KK + +GT D+ YY + +I L+ ++ +P K D Sbjct: 294 --DFTERDKKDLFEGTVDYIGFSYYMSFVIDAHRENNPYYDYLETEDL--VKNPYVKASD 349 Query: 345 WIYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQE 399 W + + P G+ L + D Y+ P ++I ENGF D + D R +Y +E Sbjct: 350 WDWQIDPQGLRYALNWFTDMYHLP-LFIVENGFGAIDQVEADGMVHDDYRIDYLGAHIKE 408 Query: 400 LFKAIQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPAR---PRVPYTSAKE 455 + KA+ D V L Y W +D G R+G +VD +D + R P S Sbjct: 409 MIKAVDEDGVELMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDEGKGTLKRSPKLSFNW 468 Query: 456 YAKIIRNNG 464 Y ++I +NG Sbjct: 469 YKEVIASNG 477 >5NAV-A nrPDB Length = 477 Score = 452 bits (1163), Expect = e-127, Method: Composition-based stats. Identities = 133/479 (27%), Positives = 215/479 (44%), Gaps = 33/479 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP GF W AAT+ Q EG + + V+D + E+ D A Y ++ Sbjct: 18 VEFPEGFVWGAATSGPQTEGNFHKQHQ--NVFDYWFATEPEQFDAGVGPDTASNFYNDYD 75 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 DL + Q G+ R S+ W+RL+ D T +N G+ +YN +ID +L + +TP + L+H Sbjct: 76 HDLALMAQAGVQGLRTSIQWTRLIDDFETASLNADGVAFYNHVIDSMLAHHITPYINLHH 135 Query: 121 FDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 FDLP L D+ GW S+ ++E F K+A+ CF FGDRV W T NE V+ Y G Sbjct: 136 FDLPVALYDKYHGWESKHVVELFVKFAEQCFKLFGDRVDHWYTFNEPKVVVDGQYLYGWH 195 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLF-RKKQKGMVSLSLFAVWLEPADPNSVS 238 P + + G Q A+N+ A A++ + L R +Q+ + L+L + A + + Sbjct: 196 YPQVIN-GPKAVQVAYNMNLASAKTVARFHELSVRPEQQIGIILNLTPAY---AASDDPA 251 Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMI- 297 D AA+ A + +LF P + G +PE + ++ L + T E +I Sbjct: 252 DLAAAEFAELWSNNLFLDPAVL-GHFPEKLVERLTM--------DGVLWDATPTELAIIA 302 Query: 298 KGTADFFAVQYYTTRLI-KYQENKKGELGILQDAEIEFFPDPSWK---NVDWIYVVPWGV 353 D V YY + + + K + D + + P + W + P + Sbjct: 303 ANPVDSLGVNYYHPFRVQRPDISPKSLQPWMPDIYFKEYDMPGRMMNVDRGW-EIYPQAM 361 Query: 354 CKLLKYIKDTYNNPVIYITENGFPQSDP-------APLDDTQRWEYFRQTFQELFKAIQL 406 + + I+ Y N I+ENG + + D R ++ ++ L K I Sbjct: 362 TDIARNIQKNYGNIPWMISENGMGVAGEERFLDKQGVVQDDYRIDFMKEHLTALAKGIAA 421 Query: 407 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 N Q Y WS +D + WN Y +R+GL D + + SAK +A++ NG Sbjct: 422 -GSNCQGYFVWSGIDCWSWNHAYHNRYGLIRNDIH--TQTKTLKKSAKWFAELGERNGF 477 >4B3K-A nrPDB Length = 479 Score = 448 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 129/478 (26%), Positives = 212/478 (44%), Gaps = 30/478 (6%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 +AFP F W AT+ Q EG + + ++D + + + + D A +Y E Sbjct: 1 LAFPKEFWWGGATSGPQSEGRFAKQHR--NLFDYWYEEEPDLFYDYVGPDTASDAYHQIE 58 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 DL + LG YR S+ W+RL+ D IN G+ YYN++ID L NG+ P++ L+H Sbjct: 59 SDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRVIDACLANGIRPVINLHH 118 Query: 121 FDLPQTL-EDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMF 179 FDLP L + GGW S+ +++ F +++ CF FGDRVK W NE V+ SY + Sbjct: 119 FDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDWFVHNEPMVVVEGSYLMQFH 178 Query: 180 PPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSD 239 P I G Q A+NL A A+ +Y + G + L PA S +D Sbjct: 179 YPAIVD-GKKAVQVAYNLALATAKVIQAYRRGPAELSDGRIGTILNLTPAYPAS-QSEAD 236 Query: 240 QEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK- 298 AA A ++ DLF + + G +PE + + + L + T EE +I Sbjct: 237 MAAAHFAELWNNDLFMEAA-VHGKFPEELVAVLKK--------DGVLWQSTPEELALIAE 287 Query: 299 GTADFFAVQYYTTRLIKYQENKKG-ELGILQDAEIEFFPDPSWK---NVDWIYVVPWGVC 354 D+ + +Y + +K + + + + P + + W + P V Sbjct: 288 NRVDYLGLNFYHPKRVKAPDAIPVISPSWSPEWYYDPYLMPGRRMNVDKGW-EIYPEAVY 346 Query: 355 KLLKYIKDTYNNPVIYITENGFPQSDP-------APLDDTQRWEYFRQTFQELFKAIQLD 407 + ++D Y+N +++ENG S + D R ++ ++ L K I+ Sbjct: 347 DIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQFLKEHLTYLHKGIEA- 405 Query: 408 KVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465 N Y W+ +D + W Y +R+GL + + R P SA + K+ +N L Sbjct: 406 GSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIH--TQVRRPKASAYWFKKVATHNRL 461 >4GZE-A nrPDB Length = 481 Score = 448 bits (1152), Expect = e-126, Method: Composition-based stats. Identities = 137/493 (27%), Positives = 222/493 (45%), Gaps = 47/493 (9%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVA--------- 52 AFP GF W A AA+Q+EGG+ GKG D T ER + G VA Sbjct: 10 AFPEGFLWGGAVAAHQLEGGYKEGGKGLSTADIMTLGTNERPREITDGVVAGKYYPNHQA 69 Query: 53 CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112 Y + ED++ ++G +R S++W+R+ P+G N+ G+ +Y+ + D+ LKNG+ Sbjct: 70 IDFYHRYPEDIELFAEMGFKCFRTSIAWTRIFPNGDESEPNEAGLQFYDDLFDECLKNGI 129 Query: 113 TPIVTLYHFDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSV 171 P+VTL HF++P L Q GGW + +I+ + +A+ CF + D+V W+T NE N + Sbjct: 130 QPVVTLAHFEMPYHLVKQYGGWRNRKLIQFYLNFAKVCFERYRDKVTYWMTFNEINNQTN 189 Query: 172 MSYDLGM-------FPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224 D M PG + YQAAH + A A + + Q G + +++ Sbjct: 190 FESDGAMLTDSGIIHQPG-ENRERWMYQAAHYELVASAAAVQLGHQINPDFQIGCM-IAM 247 Query: 225 FAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSS 284 ++ A P +D A+RA+ + + +G YP+ ++++ S Sbjct: 248 CPIYPLTAAP---ADVLFAQRAM--QTRFYFADVHCNGTYPQWLRNRFES-------EHF 295 Query: 285 RLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVD 344 L E+ K + GT D+ YY + +K G+L + E + +P K D Sbjct: 296 NLDITAEDLKILQAGTVDYIGFSYYMSFTVK----DTGKLAY--NEEHDLVKNPYVKASD 349 Query: 345 WIYVV-PWGVCKLLKYIKDTYNNPVIYITENGFPQSD----PAPLDDTQRWEYFRQTFQE 399 W + V P G+ + + D Y+ P ++I ENG D + D R +Y ++ Sbjct: 350 WGWQVDPVGLRYAMNWFTDRYHLP-LFIVENGLGAIDKKTADNQIHDDYRIDYLTDHLRQ 408 Query: 400 LFKAIQLDKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDPAR---PRVPYTSAKE 455 + A+ D V+L Y W +D + G S R+G +VD D R S Sbjct: 409 IKLAVLEDGVDLIGYTPWGCIDLVAASTGQMSKRYGFIYVDENDDGSGSLKRYKKDSFTW 468 Query: 456 YAKIIRNNGLEAH 468 + +I NG E Sbjct: 469 FQHVIATNGAEIE 481 >4IPN-B nrPDB Length = 487 Score = 446 bits (1149), Expect = e-126, Method: Composition-based stats. Identities = 124/482 (25%), Positives = 212/482 (43%), Gaps = 39/482 (8%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGD----VACGSYTL 58 FP F W A AA QVEG ++ DGKG V D G +N T D + Y Sbjct: 20 FPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEATENPTEDNLKLIGIDFYHK 79 Query: 59 WEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTL 118 ++ED+ ++G +R S++WSR+ P G N+ G+ YY+++ D+L +G+ P+VTL Sbjct: 80 YKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGLKYYDELFDELHAHGIEPLVTL 139 Query: 119 YHFDLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEAN-VLSVMSYDL 176 H++ P L + GW+ +I ++K+A+ + D+VK W+T NE N VL + Sbjct: 140 SHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYKDKVKYWLTFNEVNSVLELPFTSG 199 Query: 177 GMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNS 236 G+ P YQA H+ + A + + + + G + L++ PA P + Sbjct: 200 GIDIPKENLSKQELYQAIHHELVASSLVTKIAREINSEFKVGCMVLAM------PAYPMT 253 Query: 237 VSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296 + ++ +L+ + + G YP K EF E+ ++ Sbjct: 254 PNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKENDINI--------EFAAEDAEL 305 Query: 297 IKG-TADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVV-PWGVC 354 +K T DF + YY + + + I +P ++ +W + + P G+ Sbjct: 306 LKNYTVDFLSFSYYMSVTQSALPT---QYNSGEGNIIGGLVNPYLESSEWGWQIDPIGLR 362 Query: 355 KLLKYIKDTYNNPVIYITENGFPQSDP--------APLDDTQRWEYFRQTFQELFKAIQL 406 +L D Y P ++I ENG D + D R +Y ++ ++ +A+Q Sbjct: 363 IILNRYYDRYQIP-LFIVENGLGAKDQLIKDELNNLTVQDDYRIQYMKEHLLQVAEALQ- 420 Query: 407 DKVNLQVYCAWSLLDNFEWNQG-YSSRFGLFHVDFEDP---ARPRVPYTSAKEYAKIIRN 462 D V + Y +W +D + S R+GL +VD D R S Y ++I + Sbjct: 421 DGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRYKKMSFTWYKEVIES 480 Query: 463 NG 464 NG Sbjct: 481 NG 482 >1VFF-A nrPDB Length = 423 Score = 404 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 136/469 (28%), Positives = 217/469 (46%), Gaps = 59/469 (12%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60 + FP F + AT+++Q+EG + + W + Q G+ +++ AC + L+ Sbjct: 3 LKFPEMFLFGTATSSHQIEG----NNRWNDWW--YYEQIGKLPYRSGK---ACNHWELYR 53 Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120 +D++ + LG YRFS+ WSRL P+ N+ Y +IID LL G+TP+VTL+H Sbjct: 54 DDIQLMTSLGYNAYRFSIEWSRLFPE--ENKFNEDAFMKYREIIDLLLTRGITPLVTLHH 111 Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180 F P +GG+L E ++ ++KY + ++VK T NE V +M Y +P Sbjct: 112 FTSPLWFMKKGGFLREENLKHWEKYIEKVAELL-EKVKLVATFNEPMVYVMMGYLTAYWP 170 Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240 P I ++ A NL+KAHA ++ F+ V + + PA + D+ Sbjct: 171 PFIRS-PFKAFKVAANLLKAHAIAYELLHGKFK------VGIVKNIPIILPAS-DKERDR 222 Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300 +AA++A F I S + + + R+P+ Sbjct: 223 KAAEKADNLFNWHFLDAI--------------WSGKYRGVFKTYRIPQ----------SD 258 Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360 ADF V YYT +++ N ++ A+I + W V P G+ LK Sbjct: 259 ADFIGVNYYTASEVRHTWNPLKFFFEVKLADIS----ERKTQMGWS-VYPKGIYMALKK- 312 Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420 Y P +YITENG LDD R E+ Q Q + KAI+ D ++++ Y WS + Sbjct: 313 ASRYGRP-LYITENGIA-----TLDDEWRVEFIIQHLQYVHKAIE-DGLDVRGYFYWSFM 365 Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 DN+EW +G+ RFGL VD++ R P SA Y +I R+ ++ L Sbjct: 366 DNYEWKEGFGPRFGLVEVDYQ--TFERRPRKSAYVYGEIARSKEIKDEL 412 >4HA4-A nrPDB Length = 489 Score = 399 bits (1026), Expect = e-111, Method: Composition-based stats. Identities = 125/516 (24%), Positives = 206/516 (39%), Gaps = 92/516 (17%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV---ACGSYT 57 + FP F + + A +Q E G W + H +GD G + Sbjct: 2 VTFPKDFLFGWSQAGFQSEMGTPGSEDPNSDWYAWVHDRENIAAGLVSGDFPENGPGYWG 61 Query: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGT---------------------------TG 90 + + + +GLT R + WSR+ P T Sbjct: 62 NYRKFHDAAQAMGLTAARIGVEWSRIFPRPTFDVKVDAEVKGDDVLSVYVSEGALEQLDK 121 Query: 91 FINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQ-----------GGWLSEAII 139 N+ I++Y ++ DL G+T I+ LYH+ LP L D GWL + Sbjct: 122 MANRDAINHYREMFSDLRSRGITFILNLYHWPLPLWLHDPIAIRRGNLSAPSGWLDVRTV 181 Query: 140 ESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDL--GMFPPGIPHFGTGGYQAAHNL 197 F K++ + D V + T+NE NV+ + Y FPPG G +A NL Sbjct: 182 IEFAKFSAYVAWKLDDLVYMYSTMNEPNVVWGLGYAAVKSGFPPGYLCLECAG-RAMKNL 240 Query: 198 IKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKP 257 ++AHAR++ + ++ +K + + S F P + +D+EAA+RA F Sbjct: 241 VQAHARAYDAVKAITKKPVGVIYANSDFT-------PLTDADREAAERA-KFDNRW---- 288 Query: 258 IFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQ 317 + VV+ Q+ + + +KG D+ V YYT ++++ + Sbjct: 289 ----AFFDAVVRGQLGGST-----------------RDDLKGRLDWIGVNYYTRQVVRAR 327 Query: 318 ENK----KGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITE 373 + G + + P + W + P G+ +LK D Y+ P++ +TE Sbjct: 328 GSGYEIVPGYGHGCEPNGVSPAGRPC-SDFGWEF-YPEGLYNVLKEYWDRYHLPLL-VTE 384 Query: 374 NGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRF 433 NG D QR Y ++ +A+Q D VN+ Y WSL DN+EW G+S RF Sbjct: 385 NGIADEG-----DYQRPYYLVSHVYQVHRALQ-DGVNVIGYLHWSLADNYEWASGFSKRF 438 Query: 434 GLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 GL VD+ + SA Y +I ++ + + Sbjct: 439 GLLMVDYS--TKRLHWRPSAFIYREIAKSRAITDEI 472 >1QVB-A nrPDB Length = 481 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 124/519 (23%), Positives = 197/519 (37%), Gaps = 95/519 (18%) Query: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV---ACGSYT 57 M FP F +++ +Q E G W + H +GD G + Sbjct: 1 MKFPKDFMIGYSSSPFQFEAGIPGSEDPNSDWWVWVHDPENTAAGLVSGDFPENGPGYWN 60 Query: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGT----------------------------T 89 L + D ++LG+ R + WSR+ P T Sbjct: 61 LNQNDHDLAEKLGVNTIRVGVEWSRIFPKPTFNVKVPVERDENGSIVHVDVDDKAVERLD 120 Query: 90 GFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED------------QGGWLSEA 137 N++ +++Y ++ D ++ G I+ LYH+ LP L + GWL+E Sbjct: 121 ELANKEAVNHYVEMYKDWVERGRKLILNLYHWPLPLWLHNPIMVRRMGPDRAPSGWLNEE 180 Query: 138 IIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDL--GMFPPGIPHFGTGGYQAAH 195 + F KYA + G+ W T+NE NV+ Y G FPPG +A Sbjct: 181 SVVEFAKYAAYIAWKMGELPVMWSTMNEPNVVYEQGYMFVKGGFPPGYLSLEAAD-KARR 239 Query: 196 NLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPAD-PNSVSDQEAAKRAITFHLDLF 254 N+I+AHAR++ + +K V L W E + P V D+ + + F Sbjct: 240 NMIQAHARAYDNIKRFSKKP----VGLIYAFQWFELLEGPAEVFDKFKSSKLYYF----- 290 Query: 255 AKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLI 314 I G E ++ + D+ V YY+ + Sbjct: 291 -TDIVSKGS-----------------------SIINVEYRRDLANRLDWLGVNYYSRLVY 326 Query: 315 KYQENKK----GELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIY 370 K ++K G + I +P + W V P G+ LLK + + Y +I Sbjct: 327 KIVDDKPIILHGYGFLCTPGGISPAENPC-SDFGW-EVYPEGLYLLLKELYNRYGVDLI- 383 Query: 371 ITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYS 430 +TENG S D R Y ++KA + + ++ Y WSL DN+EW QG+ Sbjct: 384 VTENGVSDS-----RDALRPAYLVSHVYSVWKA-ANEGIPVKGYLHWSLTDNYEWAQGFR 437 Query: 431 SRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 +FGL VDF+ + R SA + +I +NG+ L Sbjct: 438 QKFGLVMVDFK--TKKRYLRPSALVFREIATHNGIPDEL 474 >3WDP-P nrPDB Length = 473 Score = 369 bits (948), Expect = e-102, Method: Composition-based stats. Identities = 119/515 (23%), Positives = 192/515 (37%), Gaps = 103/515 (20%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACG---SYTL 58 FP F + + + +Q E G W + H +GD+ + L Sbjct: 3 KFPKNFMFGYSWSGFQFEMGLPGSEV-ESDWWVWVHDKENIASGLVSGDLPENGPAYWHL 61 Query: 59 WEEDLKCIKQLGLTHYRFSLSWSRLLPDGT----------------------------TG 90 +++D ++LG+ R + W+R+ P T Sbjct: 62 YKQDHDIAEKLGMDCIRGGIEWARIFPKPTFDVKVDVEKDEEGNIISVDVPESTIKELEK 121 Query: 91 FINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQ------------GGWLSEAI 138 N + +++Y KI D + G T I+ LYH+ LP + D GWL E Sbjct: 122 IANMEALEHYRKIYSDWKERGKTFILNLYHWPLPLWIHDPIAVRKLGPDAAPAGWLDEKT 181 Query: 139 IESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY--DLGMFPPGIPHFGTGGYQAAHN 196 + F K+A F D V W T+NE NV+ Y FPPG F +A N Sbjct: 182 VVEFVKFAAFVAYHLDDLVDMWSTMNEPNVVYNQGYINLASGFPPGFLSF-EAAEKAKFN 240 Query: 197 LIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAK 256 LI+AH ++ + K V + W +P + E ++ Sbjct: 241 LIQAHIGAYDAIKEYSEKS----VGVIYAFAWHDPLAEEYKDEVEEIRKKDY-------- 288 Query: 257 PIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316 ++ ++ S KG D+ V YY+ + Sbjct: 289 ------EFVTILHS---------------------------KGKLDWIGVNYYSRLVYGA 315 Query: 317 QENKKGEL-GILQDAEIEFFPDPSWKNVDWIY-VVPWGVCKLLKYIKDTYNNPVIYITEN 374 ++ L G +E F D+ + + P G+ LLKY+ + Y P+I ITEN Sbjct: 316 KDGHLVPLPGYGFMSERGGFAKSGRPASDFGWEMYPEGLENLLKYLNNAYELPMI-ITEN 374 Query: 375 GFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFG 434 G + D R Y + ++ A++ + +++ Y WSL DN+EW QG+ RFG Sbjct: 375 GMADA-----ADRYRPHYLVSHLKAVYNAMK-EGADVRGYLHWSLTDNYEWAQGFRMRFG 428 Query: 435 LFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 L +VDFE + R SA + +I + L Sbjct: 429 LVYVDFE--TKKRYLRPSALVFREIATQKEIPEEL 461 >1GOW-A nrPDB Length = 489 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 119/514 (23%), Positives = 200/514 (38%), Gaps = 87/514 (16%) Query: 2 AFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDV---ACGSYTL 58 +FP F + + A +Q E G W + H +GD+ G + Sbjct: 3 SFPNSFRFGWSQAGFQSEMGTPGSEDPNTDWYKWVHDPENMAAGLVSGDLPENGPGYWGN 62 Query: 59 WEEDLKCIKQLGLTHYRFSLSWSRLLPDGT--------------------------TGFI 92 ++ +++GL R + WSR P+ + Sbjct: 63 YKTFHDNAQKMGLKIARLNSEWSRQFPNPLPRPQNFDESKQDVTEVEINENELKRLDEYA 122 Query: 93 NQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQ-----------GGWLSEAIIES 141 N+ +++Y +I DL G+ I +YH+ LP L D GWLS + Sbjct: 123 NKDALNHYREIFKDLKSRGLYFIQNMYHWPLPLWLHDPIRVRRGDFTGPSGWLSTRTVYE 182 Query: 142 FDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDL--GMFPPGIPHFGTGGYQAAHNLIK 199 F +++ + F D V ++ T+NE NV+ + Y FPPG F +A +N+I+ Sbjct: 183 FARFSAYTAWKFDDLVDEYSTMNEPNVVGGLGYVGVKSGFPPGYLSFEL-SRRAMYNIIQ 241 Query: 200 AHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIF 259 AHAR++ S+ +K + + S F P + D EA + A + F I Sbjct: 242 AHARAYDGIKSVSKKPVGIIYANSSF-------QPLTDKDMEAVEMAENDNRWWFFDAI- 293 Query: 260 IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQEN 319 ++ +I ++K + +KG D+ V YYT ++K E Sbjct: 294 --------IRGEITRGNEKIV-------------RDDLKGRLDWIGVNYYTRTVVKRTEK 332 Query: 320 KK----GELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENG 375 G + + P+ + W + P G+ +L + Y+ +Y+TENG Sbjct: 333 GYVSLGGYGHGCERNSVSLAGLPT-SDFGWEF-FPEGLYDVLTKYWNRYHL-YMYVTENG 389 Query: 376 FPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGL 435 D QR Y ++ +AI +++ Y WSL DN+EW G+S RFGL Sbjct: 390 IADD-----ADYQRPYYLVSHVYQVHRAINS-GADVRGYLHWSLADNYEWASGFSMRFGL 443 Query: 436 FHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469 VD+ + SA Y +I N + + Sbjct: 444 LKVDYN--TKRLYWRPSALVYREIATNGAITDEI 475 >4R27-A nrPDB Length = 434 Score = 350 bits (898), Expect = 9e-97, Method: Composition-based stats. Identities = 115/460 (25%), Positives = 182/460 (39%), Gaps = 57/460 (12%) Query: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62 FP F W ATA +QVEG + VW F +F +GD A Y + ED Sbjct: 7 FPQDFLWGVATAGHQVEG----NNVNSDVW--FLEHLPGTIFAEPSGD-AVDHYHRYRED 59 Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + I LG T YRFS+ W+R+ P+ G + +D+Y ++++ ++G+TP+VT +HF Sbjct: 60 IALIAGLGFTSYRFSVEWARIEPE--EGHFSVAALDHYKRVLEACREHGLTPVVTFHHFA 117 Query: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVM-SYDLGMFPP 181 P L GGW E E F +Y + GD + T+NE N+ ++ S+ +G P Sbjct: 118 SPLWLLRSGGWEGERTPELFARYCGRVMAHLGDLIGVACTLNEPNLPWLLESFGIGGEAP 177 Query: 182 GIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241 + W + + + E ++ + Sbjct: 178 ---------------ENRGKVPMWAAAAQRLGVDASTVAPFQFCST--EAGFNVKLAAHK 220 Query: 242 AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 AA AI H +P G + S I S+ + + + E + +G Sbjct: 221 AATEAIKAH-----RPDLRVGW--TLANSDIQSVPGGEEIAAQVRRDVNERFLEASRGD- 272 Query: 302 DFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIK 361 DF +Q Y + + G+ + E + P + ++ Sbjct: 273 DFVGIQTYGRTVYGPDGHAPAPEGVAVNQMGE-------------EIYPQALEATIREAW 319 Query: 362 DTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLD 421 PV+ +TENG DDTQR Y R + + D ++++ Y AW+ D Sbjct: 320 RVAGIPVM-VTENGLA-----TEDDTQRVAYLRTAVDGVASCLA-DGIDVRGYIAWTAFD 372 Query: 422 NFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 461 NFEW GY +FGL VD + R P SA+ R Sbjct: 373 NFEWIFGYGPKFGLIAVDRS--TQERTPKESARWLGNFAR 410 >3NCO-A nrPDB Length = 320 Score = 42.5 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 19/121 (15%) Query: 54 GSYTLWEED--LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNG 111 GS+ ++ ED K IK+ G R + WS + + I++ +D ++D LKN Sbjct: 36 GSWGVYIEDEYFKIIKERGFDSVRIPIRWSAHISEKYPYEIDKFFLDRVKHVVDVALKND 95 Query: 112 VTPIVTLYHF-DLPQTLEDQGG-----WLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165 + I+ +HF +L Q + G W + + ++F Y F NE Sbjct: 96 LVVIINCHHFEELYQAPDKYGPVLVEIW--KQVAQAFKDYPDKLFFEI---------FNE 144 Query: 166 A 166 Sbjct: 145 P 145 >4IM4-A nrPDB Length = 336 Score = 37.5 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 50/127 (39%), Gaps = 25/127 (19%) Query: 63 LKCIKQLGLTHYRFSLSW-SRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH- 120 ++ ++++G R ++W + + P I++ ++ ++++ +L G+ I+ L+H Sbjct: 42 IEKVREMGFNAVRVPVTWDTHIGPAPDY-KIDEAWLNRVEEVVNYVLDCGMYAIINLHHD 100 Query: 121 --FDLPQTLEDQGG-------WLSEAIIESFDKYAQ-FCFSTFGDRVKQWITINEANVLS 170 + +P +Q W E I F Y F T+NE + Sbjct: 101 NTWIIPTYANEQRSKEKLVKVW--EQIATRFKDYDDHLLFE----------TMNEPREVG 148 Query: 171 VMSYDLG 177 +G Sbjct: 149 SPMEWMG 155 >4UCF-A nrPDB Length = 689 Score = 37.1 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 57/160 (35%), Gaps = 41/160 (25%) Query: 46 NQTGDVACGSY--TLWEEDLKCIKQLGLTHYRFSL-SWSRLLPDGTTGFINQKGIDYYNK 102 GD + +W++D++ +K+ G+ + SW+++ P+ D+ ++ Sbjct: 21 WYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDF-----DWLDR 75 Query: 103 IIDDLLKNGV---------TP--IVTLYHFDLPQTLEDQGG--WLS-----EAIIESFDK 144 ID L K G+ +P +T H ++ +++G W F + Sbjct: 76 AIDKLGKAGIAVDLASATASPPMWLTQAHPEV-LWKDERGDTVWPGAREHWRPTSPVFRE 134 Query: 145 YA----QFCFSTFGDRVKQWITINEANVLSVM-SYDLGMF 179 YA + + V++ S + G Sbjct: 135 YALNLCRRMAEHYKG---------NPYVVAWHVSNEYGCH 165 >5H4R-A nrPDB Length = 396 Score = 35.2 bits (80), Expect = 0.063, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 49/125 (39%), Gaps = 22/125 (17%) Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122 + +K+ G R +SW + G+ I+++ +D +++D +KN + I+ ++H Sbjct: 86 IDTVKKAGFNTIRIPVSWHNHV-TGSNFTISKRWLDRVQQVVDYAMKNKMYVIINIHHDI 144 Query: 123 LP-------QTLED-----QGGWLSEAIIESFDKYAQ-FCFSTF------GDRVKQWITI 163 +P Q L+ + W + F Y F G R + W+ + Sbjct: 145 MPGYYYPNSQHLQTSIKYVKSIWT--QVATRFKNYNDHLIFEAVNQPRLTGSRFEWWLDM 202 Query: 164 NEANV 168 N Sbjct: 203 NNPEC 207 >1CEO-A nrPDB Length = 343 Score = 34.0 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 29/61 (47%) Query: 60 EEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLY 119 E+D++ I + G H R + + D G + G+ Y ++ ++ K + ++ ++ Sbjct: 31 EKDIETIAEAGFDHVRLPFDYPIIESDDNVGEYKEDGLSYIDRCLEWCKKYNLGLVLDMH 90 Query: 120 H 120 H Sbjct: 91 H 91 >4EKJ-A nrPDB Length = 500 Score = 33.6 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 45/129 (34%), Gaps = 33/129 (25%) Query: 67 KQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYN-----KIIDDLLKNGVTPIV----- 116 +LG + RF + D Q G Y+ ++ D LL G+ P + Sbjct: 52 DELGFRYIRFHA----IFHDVLGTVKVQDGKIVYDWTKIDQLYDALLAKGIKPFIELGFT 107 Query: 117 ---------TLYHFDLPQTLEDQGGWLSEAIIESFDKY--AQFCFSTFGDRVKQWI--TI 163 T++++ + G W +I++F + A++ V+ W Sbjct: 108 PEAMKTSDQTIFYWKGNTSHPKLGPW--RDLIDAFVHHLRARYGVEE----VRTWFFEVW 161 Query: 164 NEANVLSVM 172 NE N+ Sbjct: 162 NEPNLDGFW 170 >3AZS-A nrPDB Length = 317 Score = 32.9 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 46/117 (39%), Gaps = 31/117 (26%) Query: 64 KCIKQLGLTHYRFSLSWS---------RLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTP 114 IK+ G +H R + WS +++ +++I+ LK G+ Sbjct: 40 DIIKEAGFSHVRIPIRWSTHAYAFPPYKIMDRFFKRV---------DEVINGALKRGLAV 90 Query: 115 IVTLYHFDL----PQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEAN 167 ++ ++H++ P+ +++ L + I + + Y + F +NE + Sbjct: 91 VINIHHYEELMNDPEEHKERFLALWKQIADRYKDYPETLFFEI---------LNEPH 138 >4UOQ-A nrPDB Length = 695 Score = 32.1 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 54/142 (38%), Gaps = 35/142 (24%) Query: 60 EEDLKCIKQLGLTHYRFSL-SWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV------ 112 +ED++ +KQ G+ ++ SW+ + + + G +D ++ID L K G+ Sbjct: 40 DEDIRLMKQAGVNIVSLAIFSWANI--ETSDGNFEFDWLD---RVIDKLYKAGIAVDLAS 94 Query: 113 ---TP--IVTLYHFDLPQTL-EDQGG---WLS-----EAIIESFDKYA----QFCFSTFG 154 +P +T H P+ L D+ G W +F YA + + Sbjct: 95 ATASPPMWLTSAH---PEVLRRDEQGHVIWPGARQHWRPTSPTFRTYALRLCREMAEHYK 151 Query: 155 DR--VKQWITINEANVLSVMSY 174 D + W NE + Y Sbjct: 152 DNPAIVSWHVGNEYGCHNYFDY 173 >3CMG-A nrPDB Length = 667 Score = 31.7 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 24/67 (35%), Gaps = 29/67 (43%) Query: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNK---IIDDLLKNGV-- 112 EED+ ++++G+ R + +Y + + D + K+G+ Sbjct: 305 HHEEDVALMREMGVNAIR---------------------LAHYPQATYMYDLMDKHGIVT 343 Query: 113 ---TPIV 116 P V Sbjct: 344 WAEIPFV 350 >4JKL-A nrPDB Length = 602 Score = 31.3 bits (70), Expect = 0.92, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 63/206 (30%), Gaps = 50/206 (24%) Query: 263 DYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKG 322 DY E + + ++ + ++ + D + Y + + + Sbjct: 421 DYFEPLVKLYKDLDPQKRPVTLVNILMATPDRDQVMDLVDVVCLNRYYGWYVDHGDLTNA 480 Query: 323 ELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPA 382 E+ G+ K L +D + + I ITE G Sbjct: 481 EV---------------------------GIRKELLEWQDKFPDKPIIITEYGADTLP-- 511 Query: 383 PLDDTQRWEYFRQT---FQELFKAIQLDKV-NLQVYCAWSLLDNFEWN------QGYSSR 432 L T Y + F E+ + D + NL W+ D FE N QG Sbjct: 512 GLHSTWNIPYTEEFQCDFYEMSHRV-FDGIPNLVGEQVWNFAD-FETNLMILRVQGNHK- 568 Query: 433 FGLFHVDFEDPARPRVPYTSAKEYAK 458 GLF +R R P KE+ K Sbjct: 569 -GLF-------SRNRQPKQVVKEFKK 586 Score = 28.6 bits (63), Expect = 6.3, Method: Composition-based stats. Identities = 6/16 (37%), Positives = 9/16 (56%) Query: 62 DLKCIKQLGLTHYRFS 77 DL +K +G +R S Sbjct: 316 DLNLLKDMGANSFRTS 331 >5KH2-A nrPDB Length = 272 Score = 31.3 bits (70), Expect = 0.94, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 6/54 (11%) Query: 64 KCIKQLGLTH---YRFSLS-WSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVT 113 K +LG+ Y FS W+R PD FI +++Y+ + +L N V Sbjct: 77 KAANKLGVKVITVYAFSTENWTR--PDQEVKFIMNLPVEFYDNYVPELHANNVK 128 >3ZMS-C nrPDB Length = 509 Score = 31.3 bits (70), Expect = 0.98, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 9/23 (39%) Query: 389 RWEYFRQTFQELFKAIQLDKVNL 411 R Y R+ +A+Q L Sbjct: 377 RQAYLRKHLLAHHQALQAKGAPL 399 >3NJ3-A nrPDB Length = 341 Score = 31.3 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 117 TL-YHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165 TL +H LP + + W E ++ + + + S F RVK W +NE Sbjct: 102 TLVWHNQLPGWITGRE-WTKEELLNVLEDHIKTVVSHFKGRVKIWDVVNE 150 Score = 30.2 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 32/101 (31%), Gaps = 17/101 (16%) Query: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFK--AIQLDKVNLQVYCAWSLLDNFEW 425 IYITE D Y ++ + K I LD ++ W D + W Sbjct: 251 QIYITEMDVRIPLSGSED-----YYLKKQAEICAKIFDICLDNPAVKAIQFWGFTDKYSW 305 Query: 426 NQGYSSRFG---LFHVDFEDPARPRVPYTSAKEYAKIIRNN 463 G+ +G LF ++ P +++ Sbjct: 306 VPGFFKGYGKALLFDENYN-------PKPCYYAIKEVLEKK 339 >6ETZ-A nrPDB Length = 989 Score = 30.9 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 49/258 (18%), Positives = 83/258 (32%), Gaps = 55/258 (21%) Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF- 121 L+ +KQ + R S P + +Y + DL +G + Sbjct: 332 LRLMKQHNINAIRTS-----HYPPHPQFLALADQLGFYVVLECDLETHGFESAG----WA 382 Query: 122 ----DLPQT---LEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANV---LSV 171 D PQ L D+ +E +A + G NEA L+ Sbjct: 383 QNPSDDPQWEDALVDR----MRRTVERDKNHASVVMWSLG---------NEAGTGRNLAA 429 Query: 172 MSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEP 231 MS P P G + + H Y ++ + + +L +EP Sbjct: 430 MSRWTKDRDPSRPIHYEGDWSSEH---------VDVYSRMYASQAET----ALIGQGIEP 476 Query: 232 ADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTE 291 A ++ D A +RA+ F L + + G+ P + A + + E+ Sbjct: 477 ALNDAALD--ARRRAMPFVLCEY---VHAMGNGPGGMSEYQALFEKYPRLMGGFVWEWL- 530 Query: 292 EEKKMIKGTADFFAVQYY 309 E + TAD V +Y Sbjct: 531 -EHGITVSTAD--GVDHY 545 >1W3H-A nrPDB Length = 359 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 22/52 (42%), Gaps = 7/52 (13%) Query: 117 TL-YH--FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165 TL +H + LP D + + F ++ + F +VK W +NE Sbjct: 92 TLVWHPSYQLPNWASDS----NANFRQDFARHIDTVAAHFAGQVKSWDVVNE 139 >6GL0-A nrPDB Length = 331 Score = 30.2 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 49/107 (45%), Gaps = 7/107 (6%) Query: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH-- 120 + I ++G R ++W + +G I +D I + L+N + I+ ++H Sbjct: 45 IDEIAKMGFKTLRLPVTWKFHIGEGPDYLIEANWLDKVEAIANFALENEMYVIINIHHDE 104 Query: 121 -FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEA 166 + LP ++ + + + + + + A F T+GD + + T+NE Sbjct: 105 TWILPTY--EKADEVKDELSKVWTQIANR-FKTYGDYL-IFETLNEP 147 >3S1J-A nrPDB Length = 139 Score = 30.2 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 14/28 (50%), Gaps = 5/28 (17%) Query: 79 SWSRLLPDGTTGFINQKGIDYYNKIIDD 106 SW R+ P+ N+ G+ +Y + + Sbjct: 13 SWKRIEPNK-----NEIGLLFYANLFKE 35 >5E0C-A nrPDB Length = 537 Score = 30.2 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNK---IIDD 106 + A G+ + E +K I G R ++W + + IN+ D++++ +ID Sbjct: 34 ETAWGNPRVTRELIKTIADEGYKSIRIPVTWENQMGNAPDYTINE---DFFSRVEQVIDW 90 Query: 107 LLKNGVTPIVTLYH 120 L+ + ++ L+H Sbjct: 91 ALEEDLYVMLNLHH 104 >1OY5-A nrPDB Length = 257 Score = 29.8 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 26/62 (41%) Query: 312 RLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYI 371 + IK + + + + + A D + + + + P + + Y+ + Y P + I Sbjct: 29 QAIKKGKVEVYPIDLREFAPKGQVDDVPYGGLPGMVLKPEPIYEAYDYVVENYGKPFVLI 88 Query: 372 TE 373 TE Sbjct: 89 TE 90 >6ED2-A nrPDB Length = 631 Score = 29.8 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 18/51 (35%), Gaps = 10/51 (19%) Query: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDP---ARPRVPYTSAKEYAK 458 +Q W+ D + + G+ VD R R P +A + K Sbjct: 574 VQGELVWNFAD-------FQTTEGILRVDGNKKGIFTRQRQPKDAAYLFRK 617 Score = 29.0 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 5/18 (27%), Positives = 10/18 (55%) Query: 60 EEDLKCIKQLGLTHYRFS 77 + D + +K +G +R S Sbjct: 338 KRDFELMKWIGANCFRTS 355 >4V2X-A nrPDB Length = 597 Score = 29.4 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 20/137 (14%), Positives = 47/137 (34%), Gaps = 26/137 (18%) Query: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109 + A G+ + E ++ I G R ++W + I+ + ++ ++++ L+ Sbjct: 82 ETAWGNPRVTRELIEQIADEGYKSIRIPVTWENRIGGAPDYPIDPQFLNRVDQVVQWALE 141 Query: 110 NGVTPIVTLYHFDLPQTL----EDQGG--------WLSEAIIESFDKY-AQFCFSTFGDR 156 + ++ L+H D + + G W E + F Y + F + Sbjct: 142 EDLYVMINLHH-DSWLWIYEMEHNYNGVMVKYRSLW--EQLSNHFKDYPTKLMFES---- 194 Query: 157 VKQWITINEANVLSVMS 173 +NE Sbjct: 195 ------VNEPKFSQNWG 205 >4XUF-A nrPDB Length = 297 Score = 29.4 bits (65), Expect = 3.8, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 38/118 (32%), Gaps = 12/118 (10%) Query: 192 QAAHNLIKAHARSWH-----SYDSLFRKKQKGMVSLS-LFAVWLEPADPNSVSDQEAAKR 245 AA N++ H + + + + L W+ P S+ + + Sbjct: 162 LAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAP---ESLFEGIYTIK 218 Query: 246 AITFHLDLFAKPIFIDG--DYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 + + + IF G YP + + G+ + P + EE +I + Sbjct: 219 SDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQ-PFYATEEIYIIMQSC 275 >3WFX-A nrPDB Length = 138 Score = 29.0 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 21/48 (43%), Gaps = 15/48 (31%) Query: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIID 105 + E++K I++ SW R++ + G+ +Y ++ D Sbjct: 1 MTREEIKMIQK----------SWLRVIDKMD-----EAGLLFYRRLFD 33 >3ZPX-A nrPDB Length = 458 Score = 29.0 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 16/51 (31%), Gaps = 1/51 (1%) Query: 169 LSVMSYDLGMFPPGIPHFGTGGYQAAHNLI-KAHARSWHSYDSLFRKKQKG 218 + Y G G G Y HN+I A+ S F KG Sbjct: 168 IGFYGYSGGAHATGWAANLAGSYAPEHNIIGAAYGGLPASARDTFNFLNKG 218 >1E3X-A nrPDB Length = 483 Score = 29.0 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 32/108 (29%), Gaps = 13/108 (12%) Query: 307 QYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNN 366 Y+ + + + F K DW G L Y Y++ Sbjct: 146 NTYSDFKWHWYHFDGADWDESRKISRIFKFRGEGKAWDWEVSSENGNYDYLMYADVDYDH 205 Query: 367 PVIYITEN---GFPQSDPAPLDDTQRWE--------YFRQTFQELFKA 403 P + + E G ++ L D R + + R Q + +A Sbjct: 206 PDV-VAETKKWGIWYANELSL-DGFRIDAAKHIKFSFLRDWVQAVRQA 251 >3BH4-A nrPDB Length = 483 Score = 29.0 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 32/108 (29%), Gaps = 13/108 (12%) Query: 307 QYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNN 366 Y+ + + + F K DW G L Y Y++ Sbjct: 146 NTYSDFKWHWYHFDGADWDESRKISRIFKFRGEGKAWDWEVSSENGNYDYLMYADVDYDH 205 Query: 367 PVIYITEN---GFPQSDPAPLDDTQRWE--------YFRQTFQELFKA 403 P + + E G ++ L D R + + R Q + +A Sbjct: 206 PDV-VAETKKWGIWYANELSL-DGFRIDAAKHIKFSFLRDWVQAVRQA 251 >6HA9-A nrPDB Length = 396 Score = 29.0 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 10/90 (11%) Query: 49 GDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLL 108 G+ A G+ + E LK +K G R ++W + + I+ ++ +++ + Sbjct: 67 GETAWGNPMVSNELLKLVKDSGFDAVRIPVAWD-QYANQESAEISAAWLNRVKQVVQMAI 125 Query: 109 KNGVTPIVTLYHFDLPQTLEDQGGWLSEAI 138 N + ++ + H+D GGWL I Sbjct: 126 DNELYVLINI-HWD--------GGWLENNI 146 >3BES-R nrPDB Length = 250 Score = 28.6 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 26/58 (44%), Gaps = 8/58 (13%) Query: 106 DLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGD-RVKQWIT 162 L G+ T+Y ++P+ D G+ + + + K+ Q GD +V ++ T Sbjct: 27 SLRNYGIKTWQTMYT-NVPEGTYDISGFPNNDFVSFWVKFEQ------GDYKVDKYCT 77 >5X02-A nrPDB Length = 347 Score = 28.6 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 38/118 (32%), Gaps = 12/118 (10%) Query: 192 QAAHNLIKAHARSWH-----SYDSLFRKKQKGMVSLS-LFAVWLEPADPNSVSDQEAAKR 245 AA N++ H + + + + L W+ P S+ + + Sbjct: 201 LAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAP---ESLFEGIYTIK 257 Query: 246 AITFHLDLFAKPIFIDG--DYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 + + + IF G YP + + G+ + P + EE +I + Sbjct: 258 SDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQ-PFYATEEIYIIMQSC 314 >5KZW-A nrPDB Length = 874 Score = 28.6 bits (63), Expect = 6.3, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 15/37 (40%), Gaps = 7/37 (18%) Query: 133 WLSEAIIESFDKYAQFCFSTFGDRVK---QWITINEA 166 + + + ++ + F D+V WI +NE Sbjct: 412 FTNPTALAWWED----MVAEFHDQVPFDGMWIDMNEP 444 >4RT7-A nrPDB Length = 415 Score = 28.2 bits (62), Expect = 7.5, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 38/118 (32%), Gaps = 12/118 (10%) Query: 192 QAAHNLIKAHARSWH-----SYDSLFRKKQKGMVSLS-LFAVWLEPADPNSVSDQEAAKR 245 AA N++ H + + + + L W+ P S+ + + Sbjct: 269 LAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAP---ESLFEGIYTIK 325 Query: 246 AITFHLDLFAKPIFIDG--DYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301 + + + IF G YP + + G+ + P + EE +I + Sbjct: 326 SDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQ-PFYATEEIYIIMQSC 382 >1KWK-A nrPDB Length = 645 Score = 28.2 bits (62), Expect = 7.9, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Query: 58 LWEEDLKCIKQLGLTHYRFS-LSWSRLLPDG 87 W+ED + +++ GL+H R +W+ L P+ Sbjct: 15 RWKEDARRMREAGLSHVRIGEFAWALLEPEP 45 >3K4D-A nrPDB Length = 605 Score = 28.2 bits (62), Expect = 8.2, Method: Composition-based stats. Identities = 5/17 (29%), Positives = 7/17 (41%) Query: 61 EDLKCIKQLGLTHYRFS 77 D + +G YR S Sbjct: 315 HDHALMDWIGANSYRTS 331 >3RXZ-A nrPDB Length = 300 Score = 27.9 bits (61), Expect = 9.1, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 11/34 (32%) Query: 163 INEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHN 196 N V Y P I G++ AH+ Sbjct: 74 FNVPGTFFVPGYTAHRHPEPIRSIARAGHEIAHH 107 >5T99-A nrPDB Length = 822 Score = 27.9 bits (61), Expect = 9.4, Method: Composition-based stats. Identities = 5/15 (33%), Positives = 10/15 (66%) Query: 63 LKCIKQLGLTHYRFS 77 L+ +K++G+ R S Sbjct: 334 LQIMKEMGVNAIRTS 348 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.159 0.574 Lambda K H 0.267 0.0487 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,811,806 Number of Sequences: 36641 Number of extensions: 1416278 Number of successful extensions: 4322 Number of sequences better than 10.0: 102 Number of HSP's better than 10.0 without gapping: 135 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 3264 Number of HSP's gapped (non-prelim): 215 length of query: 469 length of database: 10,336,785 effective HSP length: 101 effective length of query: 368 effective length of database: 6,636,044 effective search space: 2442064192 effective search space used: 2442064192 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 62 (28.2 bits)