BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9H1D0 (765 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6BOA-A nrPDB 1501 0.0 6E2G-A nrPDB 1336 0.0 6DMR-A nrPDB 1082 0.0 2RFA-A nrPDB 404 e-113 6BBJ-A nrPDB 280 2e-75 6C8G-A nrPDB 278 7e-75 5IRX-A nrPDB 249 2e-66 6DVZ-A nrPDB 243 2e-64 6MHW-A nrPDB 238 7e-63 5AN8-A nrPDB 206 2e-53 6OO7-A nrPDB 199 5e-51 5HI9-A nrPDB 194 1e-49 6BO5-A nrPDB 194 1e-49 2ETB-A nrPDB 114 2e-25 2NYJ-A nrPDB 109 5e-24 2F37-A nrPDB 105 5e-23 3W9G-A nrPDB 103 4e-22 4DX2-A nrPDB 102 6e-22 4N5Q-A nrPDB 97 3e-20 6MWQ-A nrPDB 64 3e-10 6AUN-A nrPDB 63 5e-10 5MIO-C nrPDB 62 7e-10 5H76-A nrPDB 52 7e-07 6FES-A nrPDB 52 8e-07 5AQ9-A nrPDB 52 1e-06 5AQA-A nrPDB 50 3e-06 5AQ7-A nrPDB 50 3e-06 5AQB-A nrPDB 49 1e-05 2DWZ-A nrPDB 46 7e-05 4NIK-A nrPDB 44 2e-04 6G1K-A nrPDB 44 3e-04 5CBO-A nrPDB 42 8e-04 4OT9-A nrPDB 42 0.001 5GP7-A nrPDB 42 0.001 3B7B-A nrPDB 41 0.002 5Z96-A nrPDB 41 0.002 4Z68-A nrPDB 40 0.003 4O1O-A nrPDB 40 0.004 6CUD-A nrPDB 39 0.007 6BY9-A nrPDB 38 0.014 6BWF-A nrPDB 38 0.014 5HKP-A nrPDB 37 0.034 5JHQ-A nrPDB 37 0.039 3UI2-A nrPDB 37 0.043 4OAU-C nrPDB 36 0.064 1BLX-B nrPDB 36 0.074 3DEO-A nrPDB 35 0.085 6BPQ-A nrPDB 35 0.12 6CV9-A nrPDB 35 0.16 5DND-A nrPDB 34 0.25 1WG0-A nrPDB 33 0.38 4FZS-A nrPDB 33 0.41 1G3N-B nrPDB 32 0.99 5UQE-A nrPDB 32 1.2 5OEO-C nrPDB 31 1.5 6DU8-A nrPDB 31 2.6 5ET1-A nrPDB 30 2.6 1BD8-A nrPDB 30 2.7 5E1J-A nrPDB 30 2.9 3ZKJ-A nrPDB 30 3.5 5U0K-A nrPDB 30 3.5 5SY1-A nrPDB 30 4.0 5MKE-A nrPDB 30 5.4 5D68-A nrPDB 29 6.4 6BWI-A nrPDB 29 6.6 6AYG-A nrPDB 29 8.3 5U0J-A nrPDB 29 8.4 4DXW-A nrPDB 29 8.5 >6BOA-A nrPDB Length = 742 Score = 1501 bits (3886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/725 (99%), Positives = 724/725 (99%) Query: 41 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 100 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60 Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240 Query: 281 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 340 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300 Query: 341 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 400 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360 Query: 401 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 460 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420 Query: 461 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 520 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFA GFQMLGPFTI Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAEGFQMLGPFTI 480 Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 580 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540 Query: 581 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 640 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600 Query: 641 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 700 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660 Query: 701 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES 760 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES Sbjct: 661 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES 720 Query: 761 WEYQI 765 WEYQI Sbjct: 721 WEYQI 725 >6E2G-A nrPDB Length = 727 Score = 1336 bits (3457), Expect = 0.0, Method: Compositional matrix adjust. Identities = 650/728 (89%), Positives = 692/728 (95%), Gaps = 4/728 (0%) Query: 41 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 100 MG SLPKEKGLILCLW+KFCRWF RRESWAQSRDEQNLLQQKRIWESPLLLAAK+N+VQA Sbjct: 1 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 60 Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L KLLK+E C+VHQ+GAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 LHIAV+NQN+NLVRALLAR ASVSARATG+ F P NLIY+GEHPLSFAACV SEEIVR Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD GDHL+ L+LVPN+QG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-GGDHLKSLELVPNNQG 239 Query: 281 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 340 LTPFKLAGVEGN VMFQHLMQKRKH QWTYGPLTSTLYDLTEIDSSGD+QSLLELI+TTK Sbjct: 240 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 299 Query: 341 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 400 KREARQILDQTPVKELVSLKWKRYGRPYFC+LGAIY+LYIICFTMCC+YRPLKPR NRT Sbjct: 300 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 359 Query: 401 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 460 +PRDNTLLQQKLLQEAY+TPKDD+RLVGELV+++GA+IILLVE+PDIFR+GVTRFFGQTI Sbjct: 360 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 419 Query: 461 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 520 LGGPFHV+I+TYAFMVLVTMVMRL ++ GEVVPMSFALVLGWCNVMYFARGFQMLGPFTI Sbjct: 420 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 479 Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 580 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDP+ELGHFYDYPMALFSTFELFLTI Sbjct: 480 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 539 Query: 581 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 640 IDGPANY+VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQ+VAT Sbjct: 540 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 599 Query: 641 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRG---SE 697 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRI+RYAQAF + SE Sbjct: 600 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 659 Query: 698 DLDKDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLED 757 DL+KDS EKLE+ PF +LS P PSVSRSTSRSS NW+RLRQG LR+DL+GIINRGLED Sbjct: 660 DLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLED 719 Query: 758 GESWEYQI 765 GE WEYQI Sbjct: 720 GEGWEYQI 727 >6DMR-A nrPDB Length = 730 Score = 1082 bits (2798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 539/726 (74%), Positives = 603/726 (83%), Gaps = 12/726 (1%) Query: 41 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 100 MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAK+ND++ Sbjct: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60 Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L LL + C QRGA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA Sbjct: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 LHIAV+NQN+NLVRALLAR ASVSARATG AFRRSP NLIY+GEHPLSFAACV SEEIVR Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD H DHLQ L+LVPNHQG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240 Query: 281 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 340 LTPFKLAGVEGNTVMFQHLMQKRKH QWT GPLTSTLYDLTEIDS G+E S LEL++++K Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300 Query: 341 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 400 KREARQIL+QTPVKELVS KWK+YGRPYFC+L ++Y+LY+ICFT CCIYRPLK R +NRT Sbjct: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360 Query: 401 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 460 PRD T+LQQKLLQEAY+T +D+IRLVGELVTV GA+IILL+E+PDIFR+G +R+FGQTI Sbjct: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420 Query: 461 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 520 LGGPFHV+IITYA +VL+TMVMRL + +GEVVP+SFALVLGWC+VMYFARGFQMLGPFTI Sbjct: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480 Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 580 MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP LG F DYP ALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540 Query: 581 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 640 IDGPANY+VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQ+VAT Sbjct: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600 Query: 641 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 700 TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF ED Sbjct: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660 Query: 701 KDSVEK----LELGCPFSPHLSLPMPSVSRSTSRSSAN---WERLRQGTLRRDLRGIINR 753 + EK +E G ++ PS+SR+TS+SS + WE LR+ TL G +N Sbjct: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL-----GHLNL 715 Query: 754 GLEDGE 759 GL+ GE Sbjct: 716 GLDLGE 721 >2RFA-A nrPDB Length = 232 Score = 404 bits (1038), Expect = e-113, Method: Compositional matrix adjust. Identities = 198/221 (89%), Positives = 209/221 (94%), Gaps = 1/221 (0%) Query: 84 IWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 143 IWESPLLLAAK+NDVQAL+KLLK+E C+VHQRGAMGETALHIAALYDNLEAAMVLMEAAP Sbjct: 2 IWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 61 Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 203 ELVFEPMTSELYEGQTALHIAV+NQN+NLVRALLAR ASVSARATG+ F P NLIY+G Sbjct: 62 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 121 Query: 204 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 EHPLSFAACV SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD Sbjct: 122 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 GDHL+ L+LVPN+QGLTPFKLAGVEGN VMFQHLMQKRK Sbjct: 182 G-GDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 221 >6BBJ-A nrPDB Length = 868 Score = 280 bits (715), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 186/579 (32%), Positives = 294/579 (50%), Gaps = 68/579 (11%) Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 202 E + P Y GQTALHIA+ + + V L+ + A V A+A G F+ + YF Sbjct: 221 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 280 Query: 203 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC N +IV L E+ ADIR QDS GNTVLH L+ + N F + Sbjct: 281 GELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTK 340 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ-----------KR 303 +Y+LL+ L+ + N+ ++P +A G +FQH+++ R Sbjct: 341 VYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSR 400 Query: 304 KHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWK 362 K W YGP+ S+LYDL+ +D+ G+E S+LE+++ K E R ++L P+ EL+ KW+ Sbjct: 401 KFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQ 460 Query: 363 RYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKD 422 ++G F + YL+ +I FT+ YRP+ + T P Y T D Sbjct: 461 KFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTMD 503 Query: 423 DIRLVGELVTVIGAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLVT 479 +RL GE+VT++ ++ + + D+F GV F + G F +L Y+ +V++T Sbjct: 504 YMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIIT 559 Query: 480 MVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAV 539 V+ L+ + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + + Sbjct: 560 AVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLL 619 Query: 540 VILGFASAFYIIFQTEDPEEL-------GHFYDYPMA---------LFSTFELFLTIIDG 583 ++G+ASA + +E +YP L F+L + + D Sbjct: 620 FMIGYASALVSLLNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDL 679 Query: 584 PANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVM 643 + P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T + Sbjct: 680 EMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILD 739 Query: 644 LERKLPRCLWP--RSG---ICGREY-GLGD-RWFLRVED 675 +ER P C+ RSG G+ G D RW RV++ Sbjct: 740 IERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 778 >6C8G-A nrPDB Length = 675 Score = 278 bits (711), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 186/579 (32%), Positives = 294/579 (50%), Gaps = 68/579 (11%) Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 202 E + P Y GQTALHIA+ + + V L+ + A V A+A G F+ + YF Sbjct: 90 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 149 Query: 203 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC N +IV L E+ ADIR QDS GNTVLH L+ + N F + Sbjct: 150 GELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTK 209 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ-----------KR 303 +Y+LL+ L+ + N+ ++P +A G +FQH+++ R Sbjct: 210 VYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSR 269 Query: 304 KHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWK 362 K W YGP+ S+LYDL+ +D+ G+E S+LE+++ K E R ++L P+ EL+ KW+ Sbjct: 270 KFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQ 329 Query: 363 RYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKD 422 ++G F + YL+ +I FT+ YRP+ + T P Y T D Sbjct: 330 KFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTMD 372 Query: 423 DIRLVGELVTVIGAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLVT 479 +RL GE+VT++ ++ + + D+F GV F + G F +L Y+ +V++T Sbjct: 373 YMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIIT 428 Query: 480 MVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAV 539 V+ L+ + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + + Sbjct: 429 AVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLL 488 Query: 540 VILGFASAFYIIFQTEDPEEL-------GHFYDYPMA---------LFSTFELFLTIIDG 583 ++G+ASA + +E +YP L F+L + + D Sbjct: 489 FMIGYASALVSLLNPCTSQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDL 548 Query: 584 PANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVM 643 + P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T + Sbjct: 549 EMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILD 608 Query: 644 LERKLPRCLWP--RSG---ICGREY-GLGD-RWFLRVED 675 +ER P C+ RSG G+ G D RW RV++ Sbjct: 609 IERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 647 >5IRX-A nrPDB Length = 636 Score = 249 bits (637), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 187/578 (32%), Positives = 290/578 (50%), Gaps = 80/578 (13%) Query: 140 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCN- 198 ++ + V T Y+GQTALHIA+ +NM LV L+ A V A A G F+++ Sbjct: 79 DSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRP 138 Query: 199 LIYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKT----- 250 YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ + T Sbjct: 139 GFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTK 198 Query: 251 FACQMYNLLLSYDRHGDHLQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----- 302 F MYN +L G L P L+ + N +GLTP LA G + +++Q+ Sbjct: 199 FVTSMYNEILIL---GAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEP 255 Query: 303 ------RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELII--TTKKREARQILDQTPVK 354 RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I +++ +L P+ Sbjct: 256 ECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLN 314 Query: 355 ELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQ 414 L+ KW R+ + F +Y LY+I FT YRP++ L KL Sbjct: 315 RLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEG------------LPPYKLKN 362 Query: 415 EAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQ------TILGGPFHVL 468 T D R+ GE+++V G + F G+ F + + +L Sbjct: 363 ----TVGDYFRVTGEILSVSGGVYF--------FFRGIQYFLQRRPSLKSLFVDSYSEIL 410 Query: 469 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 528 + +LV++V+ V M F+L +GW N++Y+ RGFQ +G + +MI+KMI Sbjct: 411 FFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILR 470 Query: 529 DLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFST-FELF-LTIIDGPAN 586 DL RF ++ V + GF++A ++ ED + Y+ +L+ST ELF TI G Sbjct: 471 DLCRFMFVYLVFLFGFSTA--VVTLIEDGK-----YN---SLYSTCLELFKFTIGMGDLE 520 Query: 587 Y--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVML 644 + N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E +W+ Q T + Sbjct: 521 FTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDT 580 Query: 645 ERKLPRCLWP--RSG----ICGREYGLGD-RWFLRVED 675 E+ +C+ RSG + G D RW RV++ Sbjct: 581 EKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDE 618 >6DVZ-A nrPDB Length = 791 Score = 243 bits (620), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 164/528 (31%), Positives = 278/528 (52%), Gaps = 45/528 (8%) Query: 151 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYFGEHPLSF 209 T E YEGQTAL+IA+ + ++ L+A A V+A A G F + YFGE PL+ Sbjct: 209 TEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLAL 268 Query: 210 AACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 263 AAC N EIV+LL+E+ DI +QDS GN +LH L+ + F +MY+++L Sbjct: 269 AACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILL-- 326 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHTQWTYGP 312 R G+ L+ + N+ GLTP +LA G + ++++ + RK T W YGP Sbjct: 327 RSGN--WELETMRNNDGLTPLQLAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGP 384 Query: 313 LTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCM 371 ++S+LYDLT +D++ D S+LE+I+ + R ++L P+ L+ KWK++ + F + Sbjct: 385 VSSSLYDLTNVDTTTD-NSVLEIIVYNTNIDNRHEMLTLEPLHTLLHTKWKKFAKYMFFL 443 Query: 372 LGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELV 431 Y Y I T+ YR PR++ L L M+ ++L+G + Sbjct: 444 SFCFYFFYNITLTLVSYYR-----------PREDEDLPHPLALTHKMSW---LQLLGRMF 489 Query: 432 TVIGAIIILLVEVPDIFRMGVTRFFGQTILGGP-FHVLIITYAFMVLVTMVMRLISASGE 490 +I A I + E IF + + Q+IL FH + A +V++++ + L + Sbjct: 490 VLIWATCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEY 547 Query: 491 VVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYI 550 + + A+ LGW N++ + RGFQ +G +++MIQK+I D+++F ++ + +LGF A Sbjct: 548 LACLVLAMALGWANMLAYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALAS 607 Query: 551 IFQ--TEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIATL 608 + + ++D ++ + + A+ F+L + + D N P ++ + I+ + Sbjct: 608 LIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFV 667 Query: 609 LMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWPRS 656 L+LN+LIA+MG+T V+ E + +WR Q T + E+ LP W RS Sbjct: 668 LLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPE--WLRS 713 >6MHW-A nrPDB Length = 826 Score = 238 bits (607), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 164/528 (31%), Positives = 276/528 (52%), Gaps = 45/528 (8%) Query: 151 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYFGEHPLSF 209 T E YEGQTAL+IA+ + ++ L+A A V+A A G F + YFGE PL+ Sbjct: 210 TEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLAL 269 Query: 210 AACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 263 AAC N EIV+LL+EH DI ++DS GN +LH L+ + F +MY+++L Sbjct: 270 AACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILL-- 327 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHTQWTYGP 312 R G+ L+ N+ GLTP +LA G + ++++ + RK T W YGP Sbjct: 328 RSGN--WELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGP 385 Query: 313 LTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCM 371 ++S+LYDLT +D++ D S+LE+ + + R ++L P+ L+ +KWK++ + F + Sbjct: 386 VSSSLYDLTNVDTTTD-NSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFL 444 Query: 372 LGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELV 431 Y Y I T+ YR PR+ + L A ++L+G + Sbjct: 445 SFCFYFFYNITLTLVSYYR-----------PREEEAIPHPL---ALTHKMGWLQLLGRMF 490 Query: 432 TVIGAIIILLVEVPDIFRMGVTRFFGQTILGGP-FHVLIITYAFMVLVTMVMRLISASGE 490 +I A+ I + E IF + + Q+IL FH + A +V++++ + L + Sbjct: 491 VLIWAMCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEY 548 Query: 491 VVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYI 550 + + A+ LGW N++Y+ RGFQ +G +++MIQK+I D+++F ++ V +LGF A Sbjct: 549 LACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALAS 608 Query: 551 IFQT--EDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIATL 608 + + +D ++ + + A+ F+L + + D N P ++ + I+ + Sbjct: 609 LIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFV 668 Query: 609 LMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWPRS 656 L+LN+LIA+MG+T V+ E + +WR Q T + E+ LP W RS Sbjct: 669 LLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPE--WLRS 714 >5AN8-A nrPDB Length = 613 Score = 206 bits (525), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 180/588 (30%), Positives = 302/588 (51%), Gaps = 59/588 (10%) Query: 98 VQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAAMV-LME-----AAPE-LVFE 148 ++ L + KY + G+ G+T L A L D + A + L+E P+ LV Sbjct: 19 LEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPLVNA 78 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 T E Y G +ALHIA+ +++ V+ L+ A+V A+A G F+++ YFGE PLS Sbjct: 79 QCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLS 138 Query: 209 FAACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLL 260 AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+ LL Sbjct: 139 LAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLL 198 Query: 261 SYDRHGDHLQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQ 307 + G L P L+ +PN +GLTP KLA EG +F+H++Q+ RK T+ Sbjct: 199 ---QAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 255 Query: 308 WTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGR 366 W YGP+ +LYDL +DS +E S+LE+I + R +++ P+ +L+ KW R Sbjct: 256 WCYGPVRVSLYDLASVDS-WEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRL-I 313 Query: 367 PYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRL 426 P FC YL+Y++ FT ++P L+++ T + + L Sbjct: 314 PRFCFNFLCYLVYMLIFTAVAYHQPA---------------LEKQGFPPLKATAGNSMLL 358 Query: 427 VGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLIS 486 +G ++ ++G + +LL ++ +R + F + + F +L + A + +++ V+ ++ Sbjct: 359 LGHILILLGGVYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLCFLA 416 Query: 487 ASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 546 + + +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA Sbjct: 417 IEWYLPLLVSSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAV 476 Query: 547 AFYIIFQTEDPEELGHFYDYPMALFSTFELF-LTIIDGPANYNVDLPF--MYSITYAAFA 603 A + + +E Y L ++ ELF TI G + L F + + A+ Sbjct: 477 ALVSLSREAQEDEAP---PYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYV 533 Query: 604 IIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRC 651 ++ +L+LN+LIA+M +T VA + +W+ Q + + +E C Sbjct: 534 LLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWC 581 >6OO7-A nrPDB Length = 786 Score = 199 bits (505), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 176/599 (29%), Positives = 301/599 (50%), Gaps = 73/599 (12%) Query: 98 VQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAAMV-LME-----AAPE-LVFE 148 ++ L + KY + G+ G+T L A L D + A + L+E P+ LV Sbjct: 94 LEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPLVNA 153 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 T E Y G +ALHIA+ +++ V+ L+ A+V A+A G F+++ YFGE PLS Sbjct: 154 QCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLS 213 Query: 209 FAACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLL 260 AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+ LL Sbjct: 214 LAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLL 273 Query: 261 SYDRHGDHLQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQ 307 + G L P L+ +PN +GLTP KLA EG +F+H++Q+ RK T+ Sbjct: 274 ---QAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 330 Query: 308 WTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGR 366 W YGP+ +LYDL +D S +E S+LE+I + R +++ P+ +L+ KW R Sbjct: 331 WCYGPVRVSLYDLASVD-SWEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRL-I 388 Query: 367 PYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRL 426 P FC YL+Y++ FT ++P L+++ T + + L Sbjct: 389 PRFCFNFLCYLVYMLIFTAVAYHQP---------------ALEKQGFPPLKATAGNSMLL 433 Query: 427 VGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLIS 486 +G ++ ++G + +LL ++ +R + F + + +L + A + +++ V+ ++ Sbjct: 434 LGHILILLGGVYLLLGQLWYFWRRRL--FIWISFMDSYSEILFLLQALLTVLSQVLCFLA 491 Query: 487 ASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 546 + + +L +GW N++Y+ RGFQ G +++MI+K+I DL+RF + V + GFA Sbjct: 492 IEWYLPLLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRDLLRFLLVYLVFLFGFAV 551 Query: 547 AFYIIFQTE---------DPEELGH--------FYDYPMALFSTFELF-LTIIDGPANYN 588 A + + + E+G Y L ++ ELF TI G + Sbjct: 552 ALVSLSREAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDASLELFKFTIGMGELAFQ 611 Query: 589 VDLPF--MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLE 645 L F + + A+ ++ +L+LN+LIA+M +T VA + +W+ Q + + +E Sbjct: 612 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEME 670 >5HI9-A nrPDB Length = 770 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 190/633 (30%), Positives = 302/633 (47%), Gaps = 90/633 (14%) Query: 106 KYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LVFEPMTSELYE 156 KY + G+ G+T L A L D + A M L++ + LV T E Y+ Sbjct: 104 KYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQ 163 Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE PLS AAC Sbjct: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 Query: 217 EIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDRHGDH 268 ++V L+E+ A + A DSLGNTVLH L++ N MY+ LL + G Sbjct: 224 DVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL---QMGAR 280 Query: 269 LQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQWTYGPLTS 315 L P L+ + NHQGLTP KLA EG +F+H++Q+ RK T+W YGP+ Sbjct: 281 LCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRV 340 Query: 316 TLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCMLGA 374 +LYDL+ +DS ++ S+LE+I K R +++ P+ +L+ KW R +F A Sbjct: 341 SLYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-A 398 Query: 375 IYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVI 434 YL+Y+ FT+ ++P L Q + + T + + L+G ++ ++ Sbjct: 399 CYLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILL 443 Query: 435 GAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVVPM 494 G I +LL ++ +R + F + + F +L + A + +++ V+R + + + Sbjct: 444 GGIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLL 501 Query: 495 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY----- 549 +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 502 VLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSRE 561 Query: 550 ------------------IIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDL 591 + Q E+P D + LF TI G + L Sbjct: 562 ARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQL 616 Query: 592 PF--MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLP 649 F + + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 617 RFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYW 676 Query: 650 RCLWP--RSG----ICGREYGLGD-RWFLRVED 675 C R G + R G D RW RVE+ Sbjct: 677 WCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 709 >6BO5-A nrPDB Length = 695 Score = 194 bits (493), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 190/633 (30%), Positives = 302/633 (47%), Gaps = 90/633 (14%) Query: 106 KYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LVFEPMTSELYE 156 KY + G+ G+T L A L D + A M L++ + LV T E Y+ Sbjct: 64 KYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQ 123 Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE PLS AAC Sbjct: 124 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 183 Query: 217 EIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDRHGDH 268 ++V L+E+ A + A DSLGNTVLH L++ N MY+ LL + G Sbjct: 184 DVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL---QMGAR 240 Query: 269 LQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQWTYGPLTS 315 L P L+ + NHQGLTP KLA EG +F+H++Q+ RK T+W YGP+ Sbjct: 241 LCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRV 300 Query: 316 TLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCMLGA 374 +LYDL+ +DS ++ S+LE+I K R +++ P+ +L+ KW R +F A Sbjct: 301 SLYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-A 358 Query: 375 IYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVI 434 YL+Y+ FT+ ++P L Q + + T + + L+G ++ ++ Sbjct: 359 CYLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILL 403 Query: 435 GAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVVPM 494 G I +LL ++ +R + F + + F +L + A + +++ V+R + + + Sbjct: 404 GGIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLL 461 Query: 495 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY----- 549 +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 462 VLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSRE 521 Query: 550 ------------------IIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDL 591 + Q E+P D + LF TI G + L Sbjct: 522 ARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQL 576 Query: 592 PF--MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLP 649 F + + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 577 RFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYW 636 Query: 650 RCLWP--RSG----ICGREYGLGD-RWFLRVED 675 C R G + R G D RW RVE+ Sbjct: 637 WCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 669 >2ETB-A nrPDB Length = 256 Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 80/218 (36%), Positives = 113/218 (51%), Gaps = 23/218 (10%) Query: 106 KYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LVFEPMTSELYE 156 KY + G+ G+T L A L D + A M L++ + LV T E Y+ Sbjct: 30 KYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQ 89 Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE PLS AAC Sbjct: 90 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 149 Query: 217 EIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDRHGDH 268 ++V L+E+ A + A DSLGNTVLH L++ N MY+ LL + G Sbjct: 150 DVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL---QMGAR 206 Query: 269 LQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 L P L+ + NHQGLTP KLA EG +F+H++Q+ Sbjct: 207 LCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 244 >2NYJ-A nrPDB Length = 273 Score = 109 bits (272), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 69/178 (38%), Positives = 96/178 (53%), Gaps = 15/178 (8%) Query: 140 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNL 199 ++ + V T Y+GQTALHIA+ +NM LV L+ A V A A G F+++ Sbjct: 84 DSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRP 143 Query: 200 -IYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKT----- 250 YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ + T Sbjct: 144 GFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTK 203 Query: 251 FACQMYNLLLSYDRHGDHLQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKH 305 F MYN +L G L P L+ + N +GLTP LA G + +++Q+ H Sbjct: 204 FVTSMYNEILIL---GAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIH 258 >2F37-A nrPDB Length = 251 Score = 105 bits (263), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 78/222 (35%), Positives = 115/222 (51%), Gaps = 23/222 (10%) Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAAMVLM------EAAPE-LVFEPMT 151 L+K KY + G+ G+T L A L D + A ++ + P+ LV T Sbjct: 30 LSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCT 89 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 + Y G +ALHIA+ +++ V+ L+ A+V ARA G F++ YFGE PLS AA Sbjct: 90 DDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAA 149 Query: 212 CVNSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYD 263 C ++V L+E+ A ++A DS GNTVLH L++ N MY+ LL Sbjct: 150 CTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLL--- 206 Query: 264 RHGDHLQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 + G L P L+ + N Q LTP KLA EG +F+H++Q+ Sbjct: 207 QAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248 >3W9G-A nrPDB Length = 260 Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 65/168 (38%), Positives = 90/168 (53%), Gaps = 9/168 (5%) Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 202 E + P Y GQTALHIA+ + + V L+ + A V A+A G F+ + YF Sbjct: 80 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 139 Query: 203 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC N IV L E+G AD+R QDS GNTVLH L+ + N F + Sbjct: 140 GELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTK 199 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 MY+LLL L+ + N+ GL+P +A G +FQH++++ Sbjct: 200 MYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRR 247 >4DX2-A nrPDB Length = 259 Score = 102 bits (254), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 66/168 (39%), Positives = 90/168 (53%), Gaps = 9/168 (5%) Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 202 E + P Y GQTALHIA+ + + V L+A+ A V A+A G F+ + YF Sbjct: 78 EFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF 137 Query: 203 GEHPLSFAACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC N IV L E+ AD+R QDS GNTVLH L+ + N F + Sbjct: 138 GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTK 197 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 MY+LLL L+ V N+ GL+P +A G +FQH++++ Sbjct: 198 MYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 245 >4N5Q-A nrPDB Length = 257 Score = 97.1 bits (240), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 60/159 (37%), Positives = 91/159 (57%), Gaps = 11/159 (6%) Query: 151 TSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYFGEHPLSF 209 T E YEGQTAL+IA+ + ++ L+A A V+A A G F + YFGE PL+ Sbjct: 93 TEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLAL 152 Query: 210 AACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 263 AAC N EIV+LL+E+ DI +QDS GN +LH L+ + F +MY+++L Sbjct: 153 AACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILL-- 210 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 R G+ L+ + N+ GLTP +LA G + ++++ + Sbjct: 211 RSGNW--ELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247 >6MWQ-A nrPDB Length = 493 Score = 63.9 bits (154), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 54/174 (31%), Positives = 81/174 (46%), Gaps = 22/174 (12%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A +D++V ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 15 AGQDDEV----RILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV----NA 66 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 ++L+ GQT LH+A ++ +V LL A V+A L G+ PL A Sbjct: 67 ADLW-GQTPLHLAATAGHLEIVEVLLKYGADVNA-------------LDLIGKTPLHLTA 112 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRH 265 EIV +L++HGAD+ AQD G T I I N+ A + L LS H Sbjct: 113 IDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDIAH 166 Score = 35.8 bits (81), Expect = 0.080, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 7/94 (7%) Query: 84 IW-ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAA 142 +W ++PL LAA ++ + LLKY V+ +G+T LH+ A+ +LE VL++ Sbjct: 69 LWGQTPLHLAATAGHLEIVEVLLKY-GADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHG 127 Query: 143 PELVFEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + + ++ G+TA I++ N N +L L Sbjct: 128 AD-----VNAQDKFGKTAFDISIDNGNEDLAEIL 156 Score = 29.3 bits (64), Expect = 6.2, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 11/92 (11%) Query: 210 AACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHL 269 AA ++ VR+L+ +GAD+ A D G T LH+ + + ++ +LL + G + Sbjct: 12 AARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGH----LEIVEVLL---KCGADV 64 Query: 270 QPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ 301 DL G TP LA G+ + + L++ Sbjct: 65 NAADL----WGQTPLHLAATAGHLEIVEVLLK 92 >6AUN-A nrPDB Length = 752 Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 39/235 (16%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LA + D + L +L++Y ++ GETA H A DN + +L + A Sbjct: 154 TPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASA-- 211 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA-------TGTAFRRSPCNL 199 + +G T LH+A +VR LL A + T F + C Sbjct: 212 --GLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAE 269 Query: 200 IY--------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILIL 245 + +G PL +A + E+ R+L++ G D+ + + GNT LH+ ++ Sbjct: 270 MIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALHVAVM 326 Query: 246 QPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLM 300 + F C M +LL+Y + P G TP LA + N M + L+ Sbjct: 327 R--NRFDCVM--VLLTYGANAG-------TPGEHGNTPLHLAISKDNMEMIKALI 370 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 8/96 (8%) Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 + ++L C V A G TALH+A + + + MVL+ + G T Sbjct: 299 MARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGAN-----AGTPGEHGNTP 353 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSP 196 LH+A+ NM +++AL+ A V T F +P Sbjct: 354 LHLAISKDNMEMIKALIVFGAEVD---TPNDFGETP 386 Score = 35.8 bits (81), Expect = 0.079, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 65/155 (41%), Gaps = 28/155 (18%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGA-MGETALHIAALYDNLEAAMVLMEAAPELV 146 P+ A K + ++ + ++H + G + LH A N E A +L++ ++ Sbjct: 255 PIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCDV- 310 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH- 205 S G TALH+AV+ + V LL A+ GT GEH Sbjct: 311 ----DSTSAAGNTALHVAVMRNRFDCVMVLLTYGANA-----GTP-----------GEHG 350 Query: 206 --PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNT 238 PL A ++ E+++ LI GA++ + G T Sbjct: 351 NTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGET 385 >5MIO-C nrPDB Length = 573 Score = 62.4 bits (150), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 48/161 (29%), Positives = 76/161 (47%), Gaps = 22/161 (13%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A +D++V ++L V+ A G T LH+AA Y +LE VL++ ++ + Sbjct: 420 AGQDDEV----RVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLM 475 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 G T LH+A + ++ +V LL A V+A T +G+ PL AA Sbjct: 476 -----GSTPLHLAALIGHLEIVEVLLKHGADVNAVDT-------------WGDTPLRLAA 517 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 252 + +IV L++HGAD+ AQD G T I ++ A Sbjct: 518 VMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLA 558 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 52/175 (29%), Positives = 82/175 (46%), Gaps = 31/175 (17%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G+ L A Q+ + VR L+A A V+A G PL AA Sbjct: 411 GKKLLEAARAGQD-DEVRVLMANGADVNATDAS-------------GLTPLHLAATYGHL 456 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVP 276 EIV +L++HGAD+ A D +G+T LH+ L + ++ +LL +HG + +D Sbjct: 457 EIVEVLLKHGADVSASDLMGSTPLHLAALIGH----LEIVEVLL---KHGADVNAVDT-- 507 Query: 277 NHQGLTPFKLAGVEGNTVMFQHLMQKRK--HTQWTYGPLTSTLYDLTEIDSSGDE 329 G TP +LA V G+ + + L++ + Q +G T YD T ID+ ++ Sbjct: 508 --WGDTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGK---TAYD-TSIDNGSED 556 >5H76-A nrPDB Length = 201 Score = 52.4 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 48/161 (29%), Positives = 74/161 (45%), Gaps = 23/161 (14%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A +D++V ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 16 AGQDDEV----RILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV----DA 67 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 S+++ G T LH+A ++ +V LL A V+A + G PL AA Sbjct: 68 SDVF-GYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTPLHLAA 113 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 252 EIV +L++HGA + AQD G T I I N+ A Sbjct: 114 KWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLA 153 Score = 35.0 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 11/92 (11%) Query: 210 AACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHL 269 AA ++ VR+L+ +GAD+ A D+ G T LH+ + ++ +LL +HG + Sbjct: 13 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGH----LEIVEVLL---KHGADV 65 Query: 270 QPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ 301 D+ G TP LA G+ + + L++ Sbjct: 66 DASDVF----GYTPLHLAAYWGHLEIVEVLLK 93 >6FES-A nrPDB Length = 367 Score = 52.4 bits (124), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 22/147 (14%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A +D++V ++L V+ G T LH+AA +L VL++ ++ Sbjct: 16 AGQDDEV----RILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV-----N 66 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 + G T LH+A ++ +V LL A V+A G PL AA Sbjct: 67 ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLHLAA 113 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNT 238 EEIV +L+++GAD RAQD G T Sbjct: 114 MWGHEEIVEVLLKNGADARAQDKFGKT 140 Score = 36.2 bits (82), Expect = 0.057, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 66/145 (45%), Gaps = 25/145 (17%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G+ L A Q+ + VR LLA A V+ A T F PL AA Sbjct: 7 GKKLLEAARAGQD-DEVRILLANGADVNT-ADETGFT------------PLHLAAWEGHL 52 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVP 276 IV +L+++GAD+ A D G+T LH+ T ++ +LL ++G + D++ Sbjct: 53 GIVEVLLKNGADVNANDERGHTPLHL----AAYTGHLEIVEVLL---KNGAGVNATDVI- 104 Query: 277 NHQGLTPFKLAGVEGNTVMFQHLMQ 301 G P LA + G+ + + L++ Sbjct: 105 ---GTAPLHLAAMWGHEEIVEVLLK 126 >5AQ9-A nrPDB Length = 422 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 45/136 (33%), Positives = 61/136 (44%), Gaps = 24/136 (17%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G T LH+A + ++ +V LL A V A FG PL AA Sbjct: 47 GTTPLHLAAYSGHLEIVEVLLKHGADVDASDV-------------FGYTPLHLAAYWGHL 93 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVP 276 EIV +L+++GAD+ A DS G T LH+ K ++ +LL +HG + D Sbjct: 94 EIVEVLLKNGADVNAMDSDGMTPLHLAA----KWGYLEIVEVLL---KHGADVNAQDKF- 145 Query: 277 NHQGLTPFKLAGVEGN 292 G TPF LA GN Sbjct: 146 ---GKTPFDLADDNGN 158 Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust. Identities = 46/156 (29%), Positives = 71/156 (45%), Gaps = 23/156 (14%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA ++ + LLK+ V G T LH+AA + +LE VL++ ++ Sbjct: 49 TPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADV- 106 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 M S+ G T LH+A + +V LL A V+A+ F ++P +L Sbjct: 107 -NAMDSD---GMTPLHLAAKWGYLEIVEVLLKHGADVNAQ---DKFGKTPFDL------- 152 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 A N + V L++ A A D LG V +I Sbjct: 153 ----ADDNGNDDVGTLLQVAA---AADQLGARVGYI 181 Score = 35.4 bits (80), Expect = 0.091, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 11/93 (11%) Query: 210 AACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHL 269 AA ++ VR+L+ +GAD+ A D+ G T LH+ + ++ +LL +HG + Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGH----LEIVEVLL---KHGADV 73 Query: 270 QPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 D+ G TP LA G+ + + L++ Sbjct: 74 DASDVF----GYTPLHLAAYWGHLEIVEVLLKN 102 >5AQA-A nrPDB Length = 418 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 22/164 (13%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A +D++V ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 24 AGQDDEV----RILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD----A 75 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 S+++ G T LH+A ++ +V LL A V+A + G PL AA Sbjct: 76 SDVF-GYTPLHLAAYWGHLEIVEVLLKNGADVNA-------------MDSDGMTPLHLAA 121 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 +EIV +L++ GAD+ AQD G L + Q + A ++ Sbjct: 122 KWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKL 165 Score = 35.8 bits (81), Expect = 0.068, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 11/93 (11%) Query: 210 AACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHL 269 AA ++ VR+L+ +GAD+ A D+ G T LH+ + ++ +LL +HG + Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGH----LEIVEVLL---KHGADV 73 Query: 270 QPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 D+ G TP LA G+ + + L++ Sbjct: 74 DASDVF----GYTPLHLAAYWGHLEIVEVLLKN 102 >5AQ7-A nrPDB Length = 418 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 22/164 (13%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A +D++V ++L V+ G T LH+AA +L VL++ ++ Sbjct: 24 AGQDDEV----RILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV-----N 74 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 + G T LH+A ++ +V LL A V+A G PL AA Sbjct: 75 ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLHLAA 121 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 +EIV +L++ GAD+ AQD G L + Q + A ++ Sbjct: 122 MWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKL 165 Score = 36.2 bits (82), Expect = 0.052, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 65/145 (44%), Gaps = 25/145 (17%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G+ L A Q+ + VR LLA A V+ A T F PL AA Sbjct: 15 GKKLLEAARAGQD-DEVRILLANGADVNT-ADETGFT------------PLHLAAWEGHL 60 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVP 276 IV +L+++GAD+ A D G+T LH+ T ++ +LL ++G + D++ Sbjct: 61 GIVEVLLKNGADVNANDERGHTPLHLAAY----TGHLEIVEVLL---KNGAGVNATDVI- 112 Query: 277 NHQGLTPFKLAGVEGNTVMFQHLMQ 301 G P LA + G + + L++ Sbjct: 113 ---GTAPLHLAAMWGYKEIVEVLLK 134 >5AQB-A nrPDB Length = 428 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 19/150 (12%) Query: 103 KLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALH 162 ++L V+ +G T LH+AA + +LE L++ ++ + +G T LH Sbjct: 31 RILMANGADVNALDEVGWTPLHLAA-WGHLEIVECLLKNGADV-----NAADIDGYTPLH 84 Query: 163 IAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLL 222 +A + ++ +V LL A V+A G PL AA EIV +L Sbjct: 85 LAAFSGHLEIVEVLLKYGADVNADDQA-------------GFTPLHLAAIFGHLEIVEVL 131 Query: 223 IEHGADIRAQDSLGNTVLHILILQPNKTFA 252 +++GAD+ AQD G T + I N+ A Sbjct: 132 LKNGADVNAQDKFGKTPRDLAIDNGNEDIA 161 Score = 31.6 bits (70), Expect = 1.5, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 12/92 (13%) Query: 210 AACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHL 269 AA ++ R+L+ +GAD+ A D +G T LH+ + C + N G + Sbjct: 21 AARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKN--------GADV 72 Query: 270 QPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ 301 D+ G TP LA G+ + + L++ Sbjct: 73 NAADI----DGYTPLHLAAFSGHLEIVEVLLK 100 >2DWZ-A nrPDB Length = 231 Score = 45.8 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 57/219 (26%), Positives = 93/219 (42%), Gaps = 36/219 (16%) Query: 121 TALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARR 180 TALH A + E L++ P+ + G + LHIA +V+ALL + Sbjct: 42 TALHWACSAGHTEIVEFLLQLGV-----PVNDKDDAGWSPLHIAASAGRDEIVKALLVKG 96 Query: 181 ASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 240 A V+A ++ C PL +AA N EI +L+E GA+ A+D T + Sbjct: 97 AHVNA------VNQNGCT-------PLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAM 143 Query: 241 HILILQPNKTFACQMYNLLLSY-------DRHGDHLQPLDLVPNHQGLTPFKLAGVEGNT 293 H + N +M ++LL Y D G+ PL L + + + K +G + Sbjct: 144 HRAAAKGN----LKMVHILLFYKASTNIQDTEGN--TPLHLACDEERVEEAKFLVTQGAS 197 Query: 294 VMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSL 332 + ++ +++ Q G L L L E G+E S+ Sbjct: 198 IYIEN-KEEKTPLQVAKGGLGLILKRLAE----GEEASM 231 Score = 40.8 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 46/159 (28%), Positives = 68/159 (42%), Gaps = 25/159 (15%) Query: 87 SPLLLAA---KDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 143 SPL +AA +D V+AL L+K V+ G T LH AA + E A++L+E Sbjct: 75 SPLHIAASAGRDEIVKAL--LVK--GAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA 130 Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 203 P + Y+ TA+H A N+ +V LL +AS + + T G Sbjct: 131 ----NPDAKDHYDA-TAMHRAAAKGNLKMVHILLFYKASTNIQDTE-------------G 172 Query: 204 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 PL A E + L+ GA I ++ T L + Sbjct: 173 NTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQV 211 Score = 31.2 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 13/86 (15%) Query: 156 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 215 + +TALH A + +V LL V+ + G PL AA Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 85 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLH 241 +EIV+ L+ GA + A + G T LH Sbjct: 86 DEIVKALLVKGAHVNAVNQNGCTPLH 111 >4NIK-A nrPDB Length = 230 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 43/156 (27%), Positives = 66/156 (42%), Gaps = 19/156 (12%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SPL +AA + + LL + +V+ G T LH AA + E A++L+E Sbjct: 79 SPLHIAASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA--- 134 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 P + YE TA+H A N+ ++ LL +AS + + T G P Sbjct: 135 -NPDAKDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTE-------------GNTP 179 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 L A E +LL+ GA I ++ T L + Sbjct: 180 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 215 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 40/155 (25%), Positives = 58/155 (37%), Gaps = 51/155 (32%) Query: 121 TALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARR 180 TALH A + E L++ P+ + G + LHIA +V+ALL + Sbjct: 46 TALHWACSAGHTEIVEFLLQLGV-----PVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 100 Query: 181 ASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRA--------- 231 A V+A ++ C PL +AA N EI +L+E GA+ A Sbjct: 101 AQVNA------VNQNGCT-------PLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAM 147 Query: 232 ------------------------QDSLGNTVLHI 242 QD+ GNT LH+ Sbjct: 148 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHL 182 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 13/86 (15%) Query: 156 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 215 + +TALH A + +V LL V+ + G PL AA Sbjct: 43 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 89 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLH 241 +EIV+ L+ GA + A + G T LH Sbjct: 90 DEIVKALLGKGAQVNAVNQNGCTPLH 115 >6G1K-A nrPDB Length = 921 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 70/136 (51%), Gaps = 17/136 (12%) Query: 515 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-YIIFQTEDPEEL---GHFYDYPMAL 570 LGP I + +M+ D+++F ++ +V+L FA+ + F E+ E + G + Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNA 560 Query: 571 FST-FE----LFLTIIDGPANYNVDLP-------FMYSITYAAFAIIATLLMLNLLIAMM 618 FST FE LF +I + Y ++ F+ + + + +I+ +++LN+LIAMM Sbjct: 561 FSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMM 620 Query: 619 GDTHWRVAHERDELWR 634 +++ +A D W+ Sbjct: 621 NNSYQHIADHADIEWK 636 >5CBO-A nrPDB Length = 176 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 13/96 (13%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G T LH+A + +V LL A V+A G+ PL AA Sbjct: 36 GVTPLHLAAYWGHFEIVEVLLKYGADVNASDAT-------------GDTPLHLAAKWGYL 82 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 252 IV +L+++GAD+ AQD G T I I N+ A Sbjct: 83 GIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLA 118 Score = 42.0 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 14/86 (16%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G+ L A Q+ + VR L+A A V+A FG PL AA Sbjct: 4 GKKLLEAAHAGQD-DEVRILMANGADVNAMDN-------------FGVTPLHLAAYWGHF 49 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHI 242 EIV +L+++GAD+ A D+ G+T LH+ Sbjct: 50 EIVEVLLKYGADVNASDATGDTPLHL 75 Score = 37.4 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 6/99 (6%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA + + LLKY V+ A G+T LH+AA + L VL++ ++ Sbjct: 38 TPLHLAAYWGHFEIVEVLLKY-GADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADV- 95 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA 185 ++ G+TA I++ N N +L L +A +A Sbjct: 96 ----NAQDKFGKTAFDISIDNGNEDLAEILCKNKAQQAA 130 >4OT9-A nrPDB Length = 359 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 14/83 (16%) Query: 152 SELYEGQTALHIAVVNQNMNLVRALLAR-RASVSARATGTAFRRSPCNLIYFGEHPLSFA 210 +E G+TALH+A + + LV L+ + RA+V+AR + G PL A Sbjct: 223 TERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR-------------TFAGNTPLHLA 269 Query: 211 ACVNSEEIVRLLIEHGADIRAQD 233 A + + RLL++ GADI A++ Sbjct: 270 AGLGYPTLTRLLLKAGADIHAEN 292 Score = 32.3 bits (72), Expect = 0.89, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 33/155 (21%) Query: 119 GETALHIAALYDN---LEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRA 175 G+T LH+A ++ +E + ++ A +L +T+ L+ QT LH+AV+ ++V Sbjct: 82 GDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLH--QTPLHLAVITGQTSVVSF 139 Query: 176 LL-------------------ARRASVSARATGTAFRRSPCNLI--------YFGEHPLS 208 LL A RA A A +S + + G +P+ Sbjct: 140 LLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVH 199 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGN-TVLHI 242 A S E + LL++ GA++ A + G T LH+ Sbjct: 200 LAVRARSPECLDLLVDSGAEVEATERQGGRTALHL 234 >5GP7-A nrPDB Length = 169 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 18/157 (11%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 ++ LL AAK + + KL E+ T LH+AA Y+NLE A L+E ++ Sbjct: 10 DAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADV 69 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 ++ G LH A ++++ L+ V+A AF Sbjct: 70 -----NAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNA-TDKWAFT------------ 111 Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 PL AA ++ LL+ HGAD ++ G T L + Sbjct: 112 PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 148 >3B7B-A nrPDB Length = 237 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 47/167 (28%), Positives = 76/167 (45%), Gaps = 31/167 (18%) Query: 80 QQKRIWESPLLLAAKDNDVQALNKLLK----YEDCKVHQRGAMGETALHIAALYDNLEAA 135 Q KR SPL AA+ V + L++ + C QR T L AA ++LEA Sbjct: 9 QNKR---SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQR-----TPLMEAAENNHLEAV 60 Query: 136 MVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLAR-RASVSARATGTAFRR 194 L++A + +P +E G T LH+A + +V+ LL+ + V+ + G Sbjct: 61 KYLIKAGA--LVDPKDAE---GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----- 110 Query: 195 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 241 G P+ +A ++V+LL+ G+DI +D+ N LH Sbjct: 111 --------GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLH 149 >5Z96-A nrPDB Length = 755 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/136 (24%), Positives = 64/136 (47%), Gaps = 17/136 (12%) Query: 515 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-YIIFQTEDPEELG-------HFYDY 566 LGP I + +M+ D+++F ++ +V+L FA+ + F E+ + L + Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNA 560 Query: 567 PMALFSTFELFLTIIDGPANYNVD--------LPFMYSITYAAFAIIATLLMLNLLIAMM 618 LF T + I G N V F+ + + + +I+ +++LN+LIAMM Sbjct: 561 FSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMM 620 Query: 619 GDTHWRVAHERDELWR 634 +++ +A D W+ Sbjct: 621 NNSYQLIADHADIEWK 636 >4Z68-A nrPDB Length = 155 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 18/155 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AAK DV+ + KL + T LH AA Y+ + L++ ++ Sbjct: 7 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV--- 63 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 ++ G LH A + + L+ A V+ +L F PL Sbjct: 64 --HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNV-----------ADLWKFT--PLH 108 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 AA EI +LL++HGAD ++ GNT L ++ Sbjct: 109 EAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV 143 >4O1O-A nrPDB Length = 717 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 18/175 (10%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLL-KYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM 139 +KR +P ++A +V+ L LL ED V++ G TA AA+Y +EA L Sbjct: 71 RKRNGATPFIIAGITGNVRLLQLLLPNVED--VNECDVNGFTAFMEAAVYGRVEALRFLY 128 Query: 140 EAAPELVFEPMTSELYE-----GQTALHIAVVNQNMNLVRALL-ARRASVSARATGTAFR 193 E ++ T + E G TAL A ++ +V LL A +A V AR Sbjct: 129 ENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDN---MG 185 Query: 194 RSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 248 R+ L+Y +P A + I RLL++HGAD+ + T L + + + N Sbjct: 186 RNA--LVYALLNPDDGKA----KAITRLLLDHGADVNVRGEGSKTPLILAVERKN 234 Score = 30.0 bits (66), Expect = 4.0, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 12/65 (18%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 AV ++ VR LL R A + F+ +G PL A ++SE++V LL+ Sbjct: 15 AVQEADIEQVRQLLERGADAN-------FQEEE-----WGWSPLHSAVQMDSEDLVALLL 62 Query: 224 EHGAD 228 +HGAD Sbjct: 63 KHGAD 67 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Query: 90 LLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL D +A+ +LL V+ RG +T L +A NL+ +L+E V + Sbjct: 193 LLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDT 252 Query: 150 MTSELYEGQTALHIAVVNQNMNLVRALLARRASVS-ARATGTAFRRSPCNLIYF 202 EG+TAL +AV + + + L R AS + A R +L+ F Sbjct: 253 DR----EGKTALLLAVELRLEEIAKLLCHRGASTNCGDLVAIARRNYDSDLVKF 302 Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 12/85 (14%) Query: 217 EIVRLLIEHGADIRAQDSL-GNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 275 E VR L+E GAD Q+ G + LH + ++ LLL +HG P + Sbjct: 22 EQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVA----LLL---KHG--ADPC--L 70 Query: 276 PNHQGLTPFKLAGVEGNTVMFQHLM 300 G TPF +AG+ GN + Q L+ Sbjct: 71 RKRNGATPFIIAGITGNVRLLQLLL 95 >6CUD-A nrPDB Length = 806 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 10/147 (6%) Query: 495 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQT 554 + A+VL + + Y + GP I + + + D+ +F L +V F +I++ Sbjct: 531 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSY 589 Query: 555 EDPEELGHFYDYPMALFSTFELFLTIIDGPANYNV----DLPFMYSITYAAFAI---IAT 607 ++ + F T LF +I +V D F+ +I Y + I Sbjct: 590 YLGAKVNAAFTTVEESFKT--LFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMV 647 Query: 608 LLMLNLLIAMMGDTHWRVAHERDELWR 634 +++LN+LIAM+ ++ + + D W+ Sbjct: 648 VVLLNMLIAMINSSYQEIEDDSDVEWK 674 >6BY9-A nrPDB Length = 328 Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 76/167 (45%), Gaps = 31/167 (18%) Query: 80 QQKRIWESPLLLAAKDNDVQALNKLLK----YEDCKVHQRGAMGETALHIAALYDNLEAA 135 Q KR SPL AA+ V + L++ + C QR T L AA ++LEA Sbjct: 100 QNKR---SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQR-----TPLMEAAENNHLEAV 151 Query: 136 MVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLAR-RASVSARATGTAFRR 194 L++A + +P +E G T LH+A + +V+ LL+ + V+ + G Sbjct: 152 KYLIKAG--ALVDPKDAE---GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----- 201 Query: 195 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 241 G P+ +A ++V+LL+ G+DI +D+ N LH Sbjct: 202 --------GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLH 240 >6BWF-A nrPDB Length = 954 Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust. Identities = 56/245 (22%), Positives = 101/245 (41%), Gaps = 42/245 (17%) Query: 498 LVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTED 556 ++ + ++ F Q GP+ +MI KM+ ++ +MA+V+L F I++ E+ Sbjct: 623 IIFWYVRLLDFLAVNQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILYPHEE 681 Query: 557 PE--------------ELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAF 602 P G Y Y + + + TI GP + PF+ A + Sbjct: 682 PSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTIC-GPGTWLT--PFLQ----AVY 734 Query: 603 AIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERK--LPRCLWPRSGI-- 658 + ++M+NLLIA + + +V + +W+ Q + K LP L S I Sbjct: 735 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS 794 Query: 659 -----CGR----EYGLGDRWFLRVEDRQ---DLNRQRIQRYAQAFHTR---GSEDLDKDS 703 C R + G + FL ED++ D Q ++ Y + GSE+ + + Sbjct: 795 LFCCVCKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFDEKDDKFNSGSEERIRVT 854 Query: 704 VEKLE 708 E++E Sbjct: 855 FERVE 859 >5HKP-A nrPDB Length = 351 Score = 37.0 bits (84), Expect = 0.034, Method: Compositional matrix adjust. Identities = 18/36 (50%), Positives = 23/36 (63%) Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 241 PL AA N IV+LL++HGAD+ A+D G LH Sbjct: 61 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLH 96 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 20/108 (18%) Query: 158 QTALHIAVVN---QNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVN 214 +TALH AV + + + LL + A+V+ + N + PL AA Sbjct: 212 ETALHCAVASLHPKRKQVAELLLRKGANVNEK-----------NKDFMT--PLHVAAERA 258 Query: 215 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 262 +++ +L +HGA + A DSLG T LH L + Q LLLSY Sbjct: 259 HNDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSY 302 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 5/69 (7%) Query: 73 RDEQNLLQQKRIWESPLLLAAK--DNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYD 130 R N+ ++ + + +PL +AA+ NDV ++L K++ ++G+TALH AAL Sbjct: 235 RKGANVNEKNKDFMTPLHVAAERAHNDVM---EVLHKHGAKMNALDSLGQTALHRAALAG 291 Query: 131 NLEAAMVLM 139 +L+ +L+ Sbjct: 292 HLQTCRLLL 300 >5JHQ-A nrPDB Length = 482 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 18/36 (50%), Positives = 23/36 (63%) Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 241 PL AA N IV+LL++HGAD+ A+D G LH Sbjct: 205 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLH 240 Score = 33.9 bits (76), Expect = 0.29, Method: Compositional matrix adjust. Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 4/57 (7%) Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 262 PL AA +++ +L +HGA + A D+LG T LH L + Q LLLSY Sbjct: 394 PLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH----LQTCRLLLSY 446 Score = 29.6 bits (65), Expect = 5.5, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 5/69 (7%) Query: 73 RDEQNLLQQKRIWESPLLLAAK--DNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYD 130 R N+ ++ + + +PL +AA+ NDV ++L K++ +G+TALH AAL Sbjct: 379 RKGANVNEKNKDFMTPLHVAAERAHNDVM---EVLHKHGAKMNALDTLGQTALHRAALAG 435 Query: 131 NLEAAMVLM 139 +L+ +L+ Sbjct: 436 HLQTCRLLL 444 Score = 28.9 bits (63), Expect = 8.7, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 22/36 (61%) Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 241 PL FAA +++V L++ GA++ A+D G LH Sbjct: 52 PLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLH 87 >3UI2-A nrPDB Length = 244 Score = 36.6 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 33/99 (33%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 85 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +E+P AA+ D QAL++LL ED V G TAL A + + +L EA + Sbjct: 45 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASV 183 L M G TALH+A +V AL+ A + Sbjct: 103 LDHRDMRG----GLTALHMAAGYVRPEVVEALVELGADI 137 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 203 GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGN-TVLHI 242 G L F A + S++ VRLL E GAD+ +D G T LH+ Sbjct: 77 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHM 117 >4OAU-C nrPDB Length = 699 Score = 35.8 bits (81), Expect = 0.064, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 14/165 (8%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME 140 +K+ +P +LAA V+ L KL + V++ G TA AA+Y ++A L + Sbjct: 68 RKKNGATPFILAAIAGSVKLL-KLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYK 126 Query: 141 AAPELVFEPMTSELYE-----GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRS 195 + T E E G TAL A ++ +++ LL + A R + Sbjct: 127 RGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGA-DVNACDNMGRNA 185 Query: 196 PCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 240 LI H L + + E I LL++HGAD+ + G T L Sbjct: 186 ---LI----HALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPL 223 Score = 32.3 bits (72), Expect = 0.86, Method: Compositional matrix adjust. Identities = 46/188 (24%), Positives = 79/188 (42%), Gaps = 24/188 (12%) Query: 155 YEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVN 214 + G TA A V + ++ L R A+V+ R + L G L AA Sbjct: 103 FYGFTAFMEAAVYGKVKALKFLYKRGANVNLR---RKTKEDQERLRKGGATALMDAAEKG 159 Query: 215 SEEIVRLLI-EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLD 273 E++++L+ E GAD+ A D++G L +L + + + +LLL HG + Sbjct: 160 HVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLD---HGADVN--- 213 Query: 274 LVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLL 333 V +G TP LA + + + Q L+++ ++ + DS G LL Sbjct: 214 -VRGERGKTPLILAVEKKHLGLVQRLLEQEH-------------IEINDTDSDGKTALLL 259 Query: 334 ELIITTKK 341 + + KK Sbjct: 260 AVELKLKK 267 Score = 32.0 bits (71), Expect = 0.97, Method: Compositional matrix adjust. Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 22/138 (15%) Query: 90 LLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL++ D+DV+A+ LL V+ RG G+T L +A +L L+E + + Sbjct: 190 LLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDT 249 Query: 150 MTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSF 209 + +G+TAL +AV + + L R AS RR+ +H L Sbjct: 250 DS----DGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRNY-------DHSL-- 296 Query: 210 AACVNSEEIVRLLIEHGA 227 V++L+ HGA Sbjct: 297 ---------VKVLLSHGA 305 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 12/65 (18%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 AV N++++LV+ LL A+V+ F+ G PL A ++ E+IV LL+ Sbjct: 12 AVQNEDVDLVQQLLEGGANVN-------FQEEEG-----GWTPLHNAVQMSREDIVELLL 59 Query: 224 EHGAD 228 HGAD Sbjct: 60 RHGAD 64 >1BLX-B nrPDB Length = 166 Score = 35.8 bits (81), Expect = 0.074, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 39/81 (48%) Query: 195 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 254 SP G P+ AA + +++L+EHGAD+ A DS G+ +H+ I + + + Sbjct: 66 SPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSF 125 Query: 255 MYNLLLSYDRHGDHLQPLDLV 275 + + R L PL+L Sbjct: 126 LAPESDLHHRDASGLTPLELA 146 >3DEO-A nrPDB Length = 183 Score = 35.4 bits (80), Expect = 0.085, Method: Compositional matrix adjust. Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 11/142 (7%) Query: 85 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +E+P AA+ D QAL++LL ED V G TAL A + + +L EA + Sbjct: 44 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA----TGTAFRRSPCNLI 200 L M G TALH+A +V AL+ A + T R Sbjct: 102 LDHRDMRG----GLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTT 157 Query: 201 YFGEHPLSFAACVNSEEIVRLL 222 G +P+ F + E+++ +L Sbjct: 158 PKG-NPMQFGRRIGLEKVINVL 178 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 203 GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGN-TVLHI 242 G L F A + S++ VRLL E GAD+ +D G T LH+ Sbjct: 76 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHM 116 >6BPQ-A nrPDB Length = 950 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 25/146 (17%) Query: 515 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTED------------------ 556 LGP IM+Q+M+ D+ F +L AV ++ F A I + + Sbjct: 727 LGPKIIMLQRMMI-DVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAM 785 Query: 557 ----PEEL-GHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIAT-LLM 610 P+++ G Y++ FS E ++ AN P +I +++T +L+ Sbjct: 786 FGQYPDDIDGTTYNFDHCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILL 845 Query: 611 LNLLIAMMGDTHWRVAHERDELWRAQ 636 +NLL+AM G T V D++W+ Q Sbjct: 846 VNLLVAMFGYTVGSVQENNDQVWKFQ 871 >6CV9-A nrPDB Length = 842 Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust. Identities = 27/148 (18%), Positives = 64/148 (43%), Gaps = 12/148 (8%) Query: 495 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIF-- 552 + A+VL + + Y + GP I + + + D+ +F + +V + F + ++ Sbjct: 511 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 569 Query: 553 -----QTEDPEELGH-FYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIA 606 Q E + F A+F E+ +I+ + ++ + + Y + + Sbjct: 570 YIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGY---VLYGVYNVTM 626 Query: 607 TLLMLNLLIAMMGDTHWRVAHERDELWR 634 +++LN+LIAM+ + + + D W+ Sbjct: 627 VIVLLNMLIAMINSSFQEIEDDADVEWK 654 >5DND-A nrPDB Length = 588 Score = 33.9 bits (76), Expect = 0.25, Method: Compositional matrix adjust. Identities = 41/138 (29%), Positives = 54/138 (39%), Gaps = 22/138 (15%) Query: 99 QALNKLLKYEDCKVH---QRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELY 155 Q + +L C+ Q M AL +A + LEA LME +L + Sbjct: 400 QGVARLFSLFGCQEEDSVQDAVMPSLALALAHAGE-LEALQALMELGSDLRLKD-----S 453 Query: 156 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 215 GQT LH+A N +V LL R V+AR G PL A Sbjct: 454 NGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRD-------------GLSPLLLAVQGRH 500 Query: 216 EEIVRLLIEHGADIRAQD 233 E +RLL + GA + QD Sbjct: 501 RECIRLLRKAGACLSPQD 518 Score = 29.6 bits (65), Expect = 5.6, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 20/26 (76%) Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHI 242 E ++ L+E G+D+R +DS G T+LH+ Sbjct: 436 EALQALMELGSDLRLKDSNGQTLLHV 461 >1WG0-A nrPDB Length = 243 Score = 33.5 bits (75), Expect = 0.38, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 76/205 (37%), Gaps = 23/205 (11%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 PL A +N+ + +LL + + Q+ G LH + + E L+ + Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 148 EPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPL 207 + + G T HIA N+ +V++L R + + G L Sbjct: 65 DDYPDD--SGWTPFHIACSVGNLEVVKSLYDR-----------PLKPDLNKITNQGVTCL 111 Query: 208 SFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGD 267 A E+ + LIE+GA +R +D LH + + ++ LL + Sbjct: 112 HLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLH----RAASVGSLKLIELLCGLGKSAV 167 Query: 268 HLQPLDLVPNHQGLTPFKLAGVEGN 292 + Q + QG TP A EG+ Sbjct: 168 NWQ------DKQGWTPLFHALAEGH 186 >4FZS-A nrPDB Length = 224 Score = 33.1 bits (74), Expect = 0.41, Method: Composition-based stats. Identities = 18/46 (39%), Positives = 31/46 (67%), Gaps = 1/46 (2%) Query: 64 QRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDV-QALNKLLKYE 108 QR ++W + +D Q LQ+KR E+ LL A K + + QA +++L++E Sbjct: 114 QRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWE 159 >1G3N-B nrPDB Length = 168 Score = 32.0 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 141 PL LAAK+ ++ + L+K+ V R G+TA +A LY E + LM+A Sbjct: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158 >5UQE-A nrPDB Length = 520 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 15/142 (10%) Query: 4 LQGDGGPALGGADVAPRLSPVRVWPRPQAPKEPALHPMGLSLPKEKGLILCL-WSKFCRW 62 L G A G V P + + W P L MG S+ KG+ C C + Sbjct: 342 LPAKSGVAGGILLVVPNVMGMMCW-------SPPLDKMGNSV---KGIHFCHDLVSLCNF 391 Query: 63 --FQRRESWAQSRDEQNLLQQKRIWES-PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMG 119 + +A+ D + +R+ LL AA DV AL + + QR Sbjct: 392 HNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRF-ALSAMDMEQRDYDS 450 Query: 120 ETALHIAALYDNLEAAMVLMEA 141 TALH+AA ++E L+EA Sbjct: 451 RTALHVAAAEGHVEVVKFLLEA 472 >5OEO-C nrPDB Length = 73 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 2/28 (7%) Query: 717 LSLPMPSVSRSTSRSSAN--WERLRQGT 742 L+LP S+SR+ S+SS++ WE LRQ T Sbjct: 29 LALPTSSLSRTASQSSSHRGWEILRQNT 56 >6DU8-A nrPDB Length = 805 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/108 (22%), Positives = 50/108 (46%), Gaps = 9/108 (8%) Query: 529 DLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYN 588 D++ F + +V +A Y++F T+ + +F + +F+ F + L D A N Sbjct: 476 DILGFAVMFFIVFFAYAQLGYLLFGTQ----VENFSTFIKCIFTQFRIILGDFDYNAIDN 531 Query: 589 VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE----RDEL 632 + + + + ++LN+ +A++ DT+ V E +DEL Sbjct: 532 AN-RILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDEL 578 >5ET1-A nrPDB Length = 353 Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust. Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 18/159 (11%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME 140 Q +PL LA ++ ++ L++ H R G T LH AA + +V + Sbjct: 169 QTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGH-NPVLVWLV 227 Query: 141 AAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLI 200 + ++ F + + ++G TA+H A + ++ LL A +S Sbjct: 228 SFADVSF---SEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQD-------------- 270 Query: 201 YFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTV 239 +G PL AA E ++L +GA + +D G T Sbjct: 271 LWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTA 309 >1BD8-A nrPDB Length = 156 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 33/72 (45%) Query: 203 GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 262 G P+ AA + +++L+EHGAD+ D G +H+ + + + + + Sbjct: 68 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLH 127 Query: 263 DRHGDHLQPLDL 274 R L PL+L Sbjct: 128 RRDARGLTPLEL 139 >5E1J-A nrPDB Length = 741 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 16/79 (20%) Query: 551 IFQTEDPEE---LGHFYDYPMALFSTFELFLTIIDGPANYNV------DLP-FMYSITY- 599 +F+TE E+ L +F DYP + + F L + N+ V DL +SITY Sbjct: 598 LFETELAEDDYLLFNFNDYPNGMVTLFNLLVM-----GNWQVWMESYKDLTGTWWSITYF 652 Query: 600 AAFAIIATLLMLNLLIAMM 618 +F +I LL+LNL++A + Sbjct: 653 VSFYVITILLLLNLVVAFV 671 >3ZKJ-A nrPDB Length = 261 Score = 30.0 bits (66), Expect = 3.5, Method: Compositional matrix adjust. Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 21/152 (13%) Query: 85 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 W +PL A +N LL++ V + + +H AA ++E L+ Sbjct: 69 WHTPLFNACVSGSWDCVNLLLQH-GASVQPESDLA-SPIHEAARRGHVECVNSLIAYGGN 126 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 204 + ++ T L++A NQ V+ LL A V+ + G + Sbjct: 127 I-----DHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQ-------------D 167 Query: 205 HPLSFAACVNSEEIVRLLIEHGADIRAQDSLG 236 PL A SEE+ LL++ GAD +A+++ G Sbjct: 168 SPLHAVARTASEELACLLMDFGADTQAKNAEG 199 >5U0K-A nrPDB Length = 141 Score = 30.0 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 141 LL AA DV AL + + Q+ TALH+AA ++E L+EA Sbjct: 29 LLFAAYSGDVSALRRF-ALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEA 80 >5SY1-A nrPDB Length = 670 Score = 30.0 bits (66), Expect = 4.0, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 29/64 (45%) Query: 142 APELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIY 201 AP V P EG + IA ++ + LV A+LARR +S G SP N + Sbjct: 23 APVEVIPPCDPTADEGLFHICIAAISLVVMLVLAILARRQKLSDNQRGLTGLLSPVNFLD 82 Query: 202 FGEH 205 +H Sbjct: 83 HTQH 86 >5MKE-A nrPDB Length = 968 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 5/100 (5%) Query: 529 DLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYN 588 DL F + ++ L +A Y++F T+ + F + +F+ F + L I+ A Sbjct: 596 DLFGFAIMFFIIFLAYAQLAYLVFGTQ----VDDFSTFQECIFTQFRIILGDINF-AEIE 650 Query: 589 VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE 628 + I + F ++LN+ +A++ DT+ V + Sbjct: 651 EANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 690 >5D68-A nrPDB Length = 486 Score = 29.3 bits (64), Expect = 6.4, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 65 RRESWAQSRDEQNLLQQKRIW--ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETA 122 ++E W +S ++R W + PL +A + D + L++LL E V+Q + Sbjct: 17 KQEKWQRSMSSVTE-DKERQWVDDFPLHRSACEGDSELLSRLLS-ERFSVNQLDSDHWAP 74 Query: 123 LHIAALYDNLEAAMVLMEAA---PELVFEPMTSELYEGQTALHIAVV 166 +H A Y +EA +L+E P L+ ++S L+ H +V Sbjct: 75 IHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIV 121 >6BWI-A nrPDB Length = 977 Score = 29.3 bits (64), Expect = 6.6, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 19/31 (61%) Query: 606 ATLLMLNLLIAMMGDTHWRVAHERDELWRAQ 636 A +L++NLLIAM T +V D W+AQ Sbjct: 832 ANILLVNLLIAMFSYTFGKVQGNSDLYWKAQ 862 >6AYG-A nrPDB Length = 558 Score = 28.9 bits (63), Expect = 8.3, Method: Compositional matrix adjust. Identities = 32/163 (19%), Positives = 72/163 (44%), Gaps = 18/163 (11%) Query: 497 ALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTED 556 + +L W V+ + F + +Q + +++RFC A++ LG+ +I+ Sbjct: 385 STMLVWLGVIRYLGFFAKYNLLILTLQAAL-PNVIRFCCCAAMIYLGYCFCGWIV----- 438 Query: 557 PEELGHFYDYPMALFSTFELFLTIIDGPANYNV--------DLPFMYSITY-AAFAIIAT 607 LG ++D +L E ++I+G + L +++S Y +F + Sbjct: 439 ---LGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFI 495 Query: 608 LLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPR 650 ++L+L IA++ DT+ + + + + + T + + LP Sbjct: 496 YMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPN 538 >5U0J-A nrPDB Length = 140 Score = 28.9 bits (63), Expect = 8.4, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 141 LL AA DV AL + + QR TALH+AA ++E L+EA Sbjct: 28 LLFAAYTGDVSALRRF-ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 79 >4DXW-A nrPDB Length = 229 Score = 28.9 bits (63), Expect = 8.5, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 12/90 (13%) Query: 536 LMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLP--- 592 L+ +++ +A+ I+F +DP G D ++L + F++ LT+ + V LP Sbjct: 139 LLFIILYIYATMGAILFGNDDPSRWG---DLGISLITLFQV-LTL---SSWETVMLPMQE 191 Query: 593 -FMYSITY-AAFAIIATLLMLNLLIAMMGD 620 + +S Y +F II ++ +LNL+IA++ D Sbjct: 192 IYWWSWVYFFSFIIICSITILNLVIAILVD 221 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6BOA-A nrPDB 1122 0.0 6E2G-A nrPDB 1073 0.0 6DMR-A nrPDB 983 0.0 6BBJ-A nrPDB 615 e-176 6C8G-A nrPDB 609 e-174 5IRX-A nrPDB 592 e-169 6OO7-A nrPDB 578 e-165 5AN8-A nrPDB 574 e-164 5HI9-A nrPDB 567 e-162 6DVZ-A nrPDB 566 e-161 6BO5-A nrPDB 563 e-160 6MHW-A nrPDB 544 e-155 2RFA-A nrPDB 296 2e-80 2ETB-A nrPDB 224 1e-58 2F37-A nrPDB 221 1e-57 3W9G-A nrPDB 206 4e-53 4DX2-A nrPDB 203 2e-52 2NYJ-A nrPDB 189 3e-48 4N5Q-A nrPDB 189 3e-48 6AUN-A nrPDB 189 5e-48 6MWQ-A nrPDB 181 1e-45 5AQ9-A nrPDB 180 2e-45 5AQA-A nrPDB 177 2e-44 5H76-A nrPDB 176 4e-44 5AQB-A nrPDB 173 2e-43 5AQ7-A nrPDB 173 2e-43 6G1K-A nrPDB 173 3e-43 5MIO-C nrPDB 173 3e-43 2DWZ-A nrPDB 169 4e-42 6FES-A nrPDB 168 7e-42 4NIK-A nrPDB 163 3e-40 5Z96-A nrPDB 162 5e-40 3B7B-A nrPDB 153 2e-37 5GP7-A nrPDB 150 2e-36 5CBO-A nrPDB 126 4e-29 4OT9-A nrPDB 92 7e-19 Sequences not found previously or not previously below threshold: 6BY9-A nrPDB 153 2e-37 4Z68-A nrPDB 134 1e-31 5JHQ-A nrPDB 128 7e-30 5HKP-A nrPDB 128 8e-30 5ET1-A nrPDB 104 1e-22 4OAU-C nrPDB 103 4e-22 4O1O-A nrPDB 98 1e-20 1WG0-A nrPDB 98 2e-20 3EU9-A nrPDB 96 5e-20 6CUD-A nrPDB 95 1e-19 3ZKJ-A nrPDB 87 3e-17 6CV9-A nrPDB 84 2e-16 1BD8-A nrPDB 82 6e-16 1G3N-B nrPDB 75 1e-13 1BLX-B nrPDB 74 2e-13 6EMK-G nrPDB 74 2e-13 3LJN-A nrPDB 72 6e-13 3EHQ-A nrPDB 72 8e-13 5DND-A nrPDB 72 8e-13 5D68-A nrPDB 71 2e-12 3UI2-A nrPDB 65 1e-10 3T9K-A nrPDB 64 2e-10 3DEO-A nrPDB 64 3e-10 2KXP-C nrPDB 63 5e-10 6BPQ-A nrPDB 59 6e-09 6BWF-A nrPDB 58 1e-08 6DJS-A nrPDB 56 6e-08 4BSZ-B nrPDB 56 7e-08 5U0K-A nrPDB 55 2e-07 1D9S-A nrPDB 54 4e-07 5OEO-C nrPDB 49 6e-06 1DCQ-A nrPDB 49 1e-05 3LVQ-E nrPDB 48 1e-05 2B0O-E nrPDB 48 1e-05 2A5E-A nrPDB 48 2e-05 5U0J-A nrPDB 46 7e-05 5Z1W-A nrPDB 45 1e-04 5UQE-A nrPDB 44 2e-04 6DU8-A nrPDB 44 2e-04 5UIL-A nrPDB 42 0.001 5T4D-A nrPDB 40 0.003 5EK0-A nrPDB 40 0.003 5WPT-A nrPDB 40 0.004 5MKE-A nrPDB 40 0.004 4XD0-A nrPDB 39 0.011 4DXW-A nrPDB 38 0.017 6D1W-A nrPDB 38 0.020 6E7Z-A nrPDB 37 0.032 6AYG-A nrPDB 37 0.034 4GX0-A nrPDB 37 0.041 3RVY-A nrPDB 36 0.060 6BWI-A nrPDB 35 0.12 6N4I-A nrPDB 35 0.17 4LTR-A nrPDB 33 0.44 3S0X-A nrPDB 33 0.64 5E1J-A nrPDB 31 2.0 3CO4-A nrPDB 31 2.1 2GBW-A nrPDB 31 2.3 5AEM-A nrPDB 30 3.0 4FZS-A nrPDB 30 3.3 5HKD-A nrPDB 30 4.2 4HBK-A nrPDB 29 6.5 2FT0-A nrPDB 29 6.9 1Y1U-A nrPDB 29 8.3 >6BOA-A nrPDB Length = 742 Score = 1122 bits (2902), Expect = 0.0, Method: Composition-based stats. Identities = 724/725 (99%), Positives = 724/725 (99%) Query: 41 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 100 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60 Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240 Query: 281 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 340 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300 Query: 341 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 400 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360 Query: 401 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 460 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420 Query: 461 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 520 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFA GFQMLGPFTI Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAEGFQMLGPFTI 480 Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 580 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540 Query: 581 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 640 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600 Query: 641 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 700 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660 Query: 701 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES 760 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES Sbjct: 661 KDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLEDGES 720 Query: 761 WEYQI 765 WEYQI Sbjct: 721 WEYQI 725 >6E2G-A nrPDB Length = 727 Score = 1073 bits (2775), Expect = 0.0, Method: Composition-based stats. Identities = 650/728 (89%), Positives = 692/728 (95%), Gaps = 4/728 (0%) Query: 41 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 100 MG SLPKEKGLILCLW+KFCRWF RRESWAQSRDEQNLLQQKRIWESPLLLAAK+N+VQA Sbjct: 1 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 60 Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L KLLK+E C+VHQ+GAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 LHIAV+NQN+NLVRALLAR ASVSARATG+ F P NLIY+GEHPLSFAACV SEEIVR Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD GDHL+ L+LVPN+QG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDG-GDHLKSLELVPNNQG 239 Query: 281 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 340 LTPFKLAGVEGN VMFQHLMQKRKH QWTYGPLTSTLYDLTEIDSSGD+QSLLELI+TTK Sbjct: 240 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 299 Query: 341 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 400 KREARQILDQTPVKELVSLKWKRYGRPYFC+LGAIY+LYIICFTMCC+YRPLKPR NRT Sbjct: 300 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 359 Query: 401 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 460 +PRDNTLLQQKLLQEAY+TPKDD+RLVGELV+++GA+IILLVE+PDIFR+GVTRFFGQTI Sbjct: 360 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 419 Query: 461 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 520 LGGPFHV+I+TYAFMVLVTMVMRL ++ GEVVPMSFALVLGWCNVMYFARGFQMLGPFTI Sbjct: 420 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 479 Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 580 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDP+ELGHFYDYPMALFSTFELFLTI Sbjct: 480 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 539 Query: 581 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 640 IDGPANY+VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQ+VAT Sbjct: 540 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 599 Query: 641 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRG---SE 697 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRI+RYAQAF + SE Sbjct: 600 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 659 Query: 698 DLDKDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLED 757 DL+KDS EKLE+ PF +LS P PSVSRSTSRSS NW+RLRQG LR+DL+GIINRGLED Sbjct: 660 DLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLED 719 Query: 758 GESWEYQI 765 GE WEYQI Sbjct: 720 GEGWEYQI 727 >6DMR-A nrPDB Length = 730 Score = 983 bits (2541), Expect = 0.0, Method: Composition-based stats. Identities = 539/727 (74%), Positives = 603/727 (82%), Gaps = 12/727 (1%) Query: 41 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 100 MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAK+ND++ Sbjct: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60 Query: 101 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L LL + C QRGA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA Sbjct: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120 Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 LHIAV+NQN+NLVRALLAR ASVSARATG AFRRSP NLIY+GEHPLSFAACV SEEIVR Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD H DHLQ L+LVPNHQG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240 Query: 281 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 340 LTPFKLAGVEGNTVMFQHLMQKRKH QWT GPLTSTLYDLTEIDS G+E S LEL++++K Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300 Query: 341 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 400 KREARQIL+QTPVKELVS KWK+YGRPYFC+L ++Y+LY+ICFT CCIYRPLK R +NRT Sbjct: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360 Query: 401 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 460 PRD T+LQQKLLQEAY+T +D+IRLVGELVTV GA+IILL+E+PDIFR+G +R+FGQTI Sbjct: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420 Query: 461 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 520 LGGPFHV+IITYA +VL+TMVMRL + +GEVVP+SFALVLGWC+VMYFARGFQMLGPFTI Sbjct: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480 Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 580 MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP LG F DYP ALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540 Query: 581 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 640 IDGPANY+VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQ+VAT Sbjct: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600 Query: 641 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 700 TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF ED Sbjct: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660 Query: 701 KDSVEK----LELGCPFSPHLSLPMPSVSRSTSRSSAN---WERLRQGTLRRDLRGIINR 753 + EK +E G ++ PS+SR+TS+SS + WE LR+ TL G +N Sbjct: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL-----GHLNL 715 Query: 754 GLEDGES 760 GL+ GE Sbjct: 716 GLDLGEG 722 >6BBJ-A nrPDB Length = 868 Score = 615 bits (1585), Expect = e-176, Method: Composition-based stats. Identities = 195/640 (30%), Positives = 314/640 (49%), Gaps = 77/640 (12%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALY---DNLEAAMVLMEAAP----- 143 A + + L K + + + G+T L A + + +L++ A Sbjct: 160 AELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLNGGKNDTIPMLIDIAEKTGNL 219 Query: 144 -ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIY 201 E + P Y GQTALHIA+ + + V L+ + A V A+A G F+ + Y Sbjct: 220 REFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFY 279 Query: 202 FGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFAC 253 FGE PLS AAC N +IV L E+ ADIR QDS GNTVLH L+ + N F Sbjct: 280 FGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVT 339 Query: 254 QMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ-----------K 302 ++Y+LL+ L+ + N+ ++P +A G +FQH+++ Sbjct: 340 KVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLS 399 Query: 303 RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKW 361 RK W YGP+ S+LYDL+ +D+ G+E S+LE+++ K E R ++L P+ EL+ KW Sbjct: 400 RKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKW 459 Query: 362 KRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPK 421 +++G F + YL+ +I FT+ YRP+ + T P Y T Sbjct: 460 QKFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTM 502 Query: 422 DDIRLVGELVTVIGAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLV 478 D +RL GE+VT++ ++ + + D+F GV F + G F +L Y+ +V++ Sbjct: 503 DYMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVII 558 Query: 479 TMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMA 538 T V+ L+ + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + Sbjct: 559 TAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYL 618 Query: 539 VVILGFASAFYIIFQTEDPEEL-------GHFYDYPMA---------LFSTFELFLTIID 582 + ++G+ASA + +E +YP L F+L + + D Sbjct: 619 LFMIGYASALVSLLNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGD 678 Query: 583 GPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTV 642 + P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T + Sbjct: 679 LEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTIL 738 Query: 643 MLERKLPRCLWP--RSG---ICGRE-YGLGD-RWFLRVED 675 +ER P C+ RSG G+ G D RW RV++ Sbjct: 739 DIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 778 >6C8G-A nrPDB Length = 675 Score = 609 bits (1569), Expect = e-174, Method: Composition-based stats. Identities = 195/640 (30%), Positives = 314/640 (49%), Gaps = 77/640 (12%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALY---DNLEAAMVLMEAAP----- 143 A + + L K + + + G+T L A + + +L++ A Sbjct: 29 AELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLNGGKNDTIPMLIDIAEKTGNL 88 Query: 144 -ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIY 201 E + P Y GQTALHIA+ + + V L+ + A V A+A G F+ + Y Sbjct: 89 REFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFY 148 Query: 202 FGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFAC 253 FGE PLS AAC N +IV L E+ ADIR QDS GNTVLH L+ + N F Sbjct: 149 FGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVT 208 Query: 254 QMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQ-----------K 302 ++Y+LL+ L+ + N+ ++P +A G +FQH+++ Sbjct: 209 KVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLS 268 Query: 303 RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKW 361 RK W YGP+ S+LYDL+ +D+ G+E S+LE+++ K E R ++L P+ EL+ KW Sbjct: 269 RKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKW 328 Query: 362 KRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPK 421 +++G F + YL+ +I FT+ YRP+ + T P Y T Sbjct: 329 QKFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTM 371 Query: 422 DDIRLVGELVTVIGAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLV 478 D +RL GE+VT++ ++ + + D+F GV F + G F +L Y+ +V++ Sbjct: 372 DYMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVII 427 Query: 479 TMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMA 538 T V+ L+ + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + Sbjct: 428 TAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYL 487 Query: 539 VVILGFASAFYIIFQTEDPEEL-------GHFYDYPMA---------LFSTFELFLTIID 582 + ++G+ASA + +E +YP L F+L + + D Sbjct: 488 LFMIGYASALVSLLNPCTSQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGD 547 Query: 583 GPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTV 642 + P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T + Sbjct: 548 LEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTIL 607 Query: 643 MLERKLPRCLWP--RSG---ICGRE-YGLGD-RWFLRVED 675 +ER P C+ RSG G+ G D RW RV++ Sbjct: 608 DIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 647 >5IRX-A nrPDB Length = 636 Score = 592 bits (1526), Expect = e-169, Method: Composition-based stats. Identities = 184/638 (28%), Positives = 297/638 (46%), Gaps = 65/638 (10%) Query: 78 LLQQKRIWESPLLLAAKDND--VQALNKLLKYEDCKVHQRGAMGETALHIAALY---DNL 132 L ++ I+++ ++ + + L + K + G+T L A L Sbjct: 6 LYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQN 65 Query: 133 EAAMVLMEAA------PELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSAR 186 + +L++ A + V T Y+GQTALHIA+ +NM LV L+ A V A Sbjct: 66 DTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAA 125 Query: 187 ATGTAFRRSPCN-LIYFGEHPLSFAACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHI 242 A G F+++ YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH Sbjct: 126 ANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHA 185 Query: 243 LILQP-----NKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQ 297 L+ N F MYN +L L+ + N +GLTP LA G + Sbjct: 186 LVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLA 245 Query: 298 HLMQK-----------RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK--KREA 344 +++Q+ RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I + Sbjct: 246 YILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNR 304 Query: 345 RQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRD 404 +L P+ L+ KW R+ + F +Y LY+I FT YRP++ Sbjct: 305 HDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEG---------- 354 Query: 405 NTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGP 464 L KL T D R+ GE+++V G + + + + + Sbjct: 355 --LPPYKLKN----TVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPS--LKSLFVDSY 406 Query: 465 FHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK 524 +L + +LV++V+ V M F+L +GW N++Y+ RGFQ +G + +MI+K Sbjct: 407 SEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEK 466 Query: 525 MIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGP 584 MI DL RF ++ V + GF++A + E G + F+ + + D Sbjct: 467 MILRDLCRFMFVYLVFLFGFSTAVVTLI------EDGKYNSLYSTCLELFKFTIGMGDLE 520 Query: 585 ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVML 644 N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E +W+ Q T + Sbjct: 521 FTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDT 580 Query: 645 ERKLPRCLWP--RSG----ICGREYGLGD-RWFLRVED 675 E+ +C+ RSG + G D RW RV++ Sbjct: 581 EKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDE 618 >6OO7-A nrPDB Length = 786 Score = 578 bits (1489), Expect = e-165, Method: Composition-based stats. Identities = 180/636 (28%), Positives = 303/636 (47%), Gaps = 74/636 (11%) Query: 95 DNDVQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------L 145 ++ L + KY + G+ G+T L A L D + A L+E + L Sbjct: 91 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 150 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 V T E Y G +ALHIA+ +++ V+ L+ A+V A+A G F+++ YFGE Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210 Query: 206 PLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 257 PLS AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+ Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270 Query: 258 LLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQ 307 LL L+ +PN +GLTP KLA EG +F+H++Q+ RK T+ Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 330 Query: 308 WTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGR 366 W YGP+ +LYDL +DS +E S+LE+I + R +++ P+ +L+ KW R Sbjct: 331 WCYGPVRVSLYDLASVDS-WEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLI- 388 Query: 367 PYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRL 426 P FC YL+Y++ FT ++P L+++ T + + L Sbjct: 389 PRFCFNFLCYLVYMLIFTAVAYHQPA---------------LEKQGFPPLKATAGNSMLL 433 Query: 427 VGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLIS 486 +G ++ ++G + +LL ++ +R + F + + +L + A + +++ V+ ++ Sbjct: 434 LGHILILLGGVYLLLGQLWYFWRRRL--FIWISFMDSYSEILFLLQALLTVLSQVLCFLA 491 Query: 487 ASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 546 + + +L +GW N++Y+ RGFQ G +++MI+K+I DL+RF + V + GFA Sbjct: 492 IEWYLPLLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRDLLRFLLVYLVFLFGFAV 551 Query: 547 AFYIIFQTEDPEELG-----------------HFYDYPMALFSTFELF-LTIIDGPANYN 588 A + + Y L ++ ELF TI G + Sbjct: 552 ALVSLSREAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDASLELFKFTIGMGELAFQ 611 Query: 589 VDLPFMY--SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLER 646 L F + A+ ++ +L+LN+LIA+M +T VA + +W+ Q + + +E Sbjct: 612 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMEN 671 Query: 647 KLPRCLWP--RSG----ICGREYGLGD-RWFLRVED 675 C R+G + R G D RW RV + Sbjct: 672 GYWWCRRKKQRAGVMLTVGTRPDGSPDERWCFRVGE 707 >5AN8-A nrPDB Length = 613 Score = 574 bits (1480), Expect = e-164, Method: Composition-based stats. Identities = 185/619 (29%), Positives = 307/619 (49%), Gaps = 60/619 (9%) Query: 95 DNDVQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------L 145 ++ L + KY + G+ G+T L A L D + A L+E + L Sbjct: 16 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 75 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 V T E Y G +ALHIA+ +++ V+ L+ A+V A+A G F+++ YFGE Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135 Query: 206 PLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 257 PLS AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+ Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195 Query: 258 LLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQ 307 LL L+ +PN +GLTP KLA EG +F+H++Q+ RK T+ Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 255 Query: 308 WTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGR 366 W YGP+ +LYDL +DS +E S+LE+I + R +++ P+ +L+ KW R Sbjct: 256 WCYGPVRVSLYDLASVDS-WEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLI- 313 Query: 367 PYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRL 426 P FC YL+Y++ FT ++P L+++ T + + L Sbjct: 314 PRFCFNFLCYLVYMLIFTAVAYHQPA---------------LEKQGFPPLKATAGNSMLL 358 Query: 427 VGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLIS 486 +G ++ ++G + +LL ++ +R + F + + F +L + A + +++ V+ ++ Sbjct: 359 LGHILILLGGVYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLCFLA 416 Query: 487 ASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 546 + + +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA Sbjct: 417 IEWYLPLLVSSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAV 476 Query: 547 AFYIIFQTEDPEELGHFYDYPMALFSTFELF-LTIIDGPANYNVDLPFMY--SITYAAFA 603 A + + +E Y L ++ ELF TI G + L F + A+ Sbjct: 477 ALVSLSREAQEDEA---PPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYV 533 Query: 604 IIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWP--RSG---- 657 ++ +L+LN+LIA+M +T VA + +W+ Q + + +E C R+G Sbjct: 534 LLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRRKKQRAGVMLT 593 Query: 658 ICGREYGLGD-RWFLRVED 675 + R G D RW RV + Sbjct: 594 VGTRPDGSPDERWCFRVGE 612 >5HI9-A nrPDB Length = 770 Score = 567 bits (1460), Expect = e-162, Method: Composition-based stats. Identities = 187/635 (29%), Positives = 301/635 (47%), Gaps = 74/635 (11%) Query: 96 NDVQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LV 146 ++ L KY + G+ G+T L A L D + A M L++ + LV Sbjct: 94 GLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLV 153 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 T E Y+G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE P Sbjct: 154 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 213 Query: 207 LSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNL 258 LS AAC ++V L+E+ A + A DSLGNTVLH L++ N MY+ Sbjct: 214 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 273 Query: 259 LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQW 308 LL L+ + NHQGLTP KLA EG +F+H++Q+ RK T+W Sbjct: 274 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEW 333 Query: 309 TYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRP 367 YGP+ +LYDL+ +DS ++ S+LE+I K R +++ P+ +L+ KW R Sbjct: 334 CYGPVRVSLYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSR 392 Query: 368 YFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLV 427 F A YL+Y+ FT+ ++P L Q + + T + + L+ Sbjct: 393 -FFFNFACYLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLL 436 Query: 428 GELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISA 487 G ++ ++G I +LL ++ +R + F + + F +L + A + +++ V+R + Sbjct: 437 GHILILLGGIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMET 494 Query: 488 SGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASA 547 + + +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 495 EWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVA 554 Query: 548 FYIIFQTEDPEELGHFYD-----------------YPMALFSTFELF-LTIIDGPANYNV 589 + + + + Y L ++ ELF TI G + Sbjct: 555 LVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQE 614 Query: 590 DLPFMY--SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERK 647 L F + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 615 QLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENG 674 Query: 648 LPRCLWP--RSG----ICGREYGLGD-RWFLRVED 675 C R G + R G D RW RVE+ Sbjct: 675 YWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 709 >6DVZ-A nrPDB Length = 791 Score = 566 bits (1459), Expect = e-161, Method: Composition-based stats. Identities = 179/635 (28%), Positives = 304/635 (47%), Gaps = 69/635 (10%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVH---------------QRGAMGETALHIAALY---D 130 + A + V+ L +LL+ G+T L A L + Sbjct: 123 IFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPN 182 Query: 131 NLEAAMVLMEAAPE------LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS 184 E +L+ A E + T E YEGQTAL+IA+ + ++ L+A A V+ Sbjct: 183 TKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVN 242 Query: 185 ARATGTAFR-RSPCNLIYFGEHPLSFAACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHI 242 A A G F + YFGE PL+ AAC N EIV+LL+E+ DI +QDS GN +LH Sbjct: 243 AHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHA 302 Query: 243 LI-----LQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQ 297 L+ + F +MY+++L + L+ + N+ GLTP +LA G + + Sbjct: 303 LVTVAEDFKTQNDFVKRMYDMILLRSGN----WELETMRNNDGLTPLQLAAKMGKAEILK 358 Query: 298 HLMQK-----------RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR- 345 +++ + RK T W YGP++S+LYDLT +D++ D S+LE+I+ + R Sbjct: 359 YILSREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTD-NSVLEIIVYNTNIDNRH 417 Query: 346 QILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDN 405 ++L P+ L+ KWK++ + F + Y Y I T+ YRP R++ Sbjct: 418 EMLTLEPLHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRP-----------RED 466 Query: 406 TLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTIL-GGP 464 L L M+ ++L+G + +I A I + E IF + + Q+IL Sbjct: 467 EDLPHPLALTHKMSW---LQLLGRMFVLIWATCISVKEGIAIFLLRPSDL--QSILSDAW 521 Query: 465 FHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK 524 FH + A +V++++ + L + + + A+ LGW N++ + RGFQ +G +++MIQK Sbjct: 522 FHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLAYTRGFQSMGMYSVMIQK 581 Query: 525 MIFGDLMRFCWLMAVVILGFASAFYIIFQTE--DPEELGHFYDYPMALFSTFELFLTIID 582 +I D+++F ++ + +LGF A + + D ++ + + A+ F+L + + D Sbjct: 582 VILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGD 641 Query: 583 GPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTV 642 N P ++ + I+ +L+LN+LIA+MG+T V+ E + +WR Q T + Sbjct: 642 LNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTIL 701 Query: 643 MLERKLPRCLWP--RSGICGREYGLGDRWFLRVED 675 E+ LP L R G + R LR+ + Sbjct: 702 EFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINE 736 >6BO5-A nrPDB Length = 695 Score = 563 bits (1451), Expect = e-160, Method: Composition-based stats. Identities = 187/635 (29%), Positives = 301/635 (47%), Gaps = 74/635 (11%) Query: 96 NDVQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LV 146 ++ L KY + G+ G+T L A L D + A M L++ + LV Sbjct: 54 GLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLV 113 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 T E Y+G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE P Sbjct: 114 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 173 Query: 207 LSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNL 258 LS AAC ++V L+E+ A + A DSLGNTVLH L++ N MY+ Sbjct: 174 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 233 Query: 259 LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQW 308 LL L+ + NHQGLTP KLA EG +F+H++Q+ RK T+W Sbjct: 234 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEW 293 Query: 309 TYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRP 367 YGP+ +LYDL+ +DS ++ S+LE+I K R +++ P+ +L+ KW R Sbjct: 294 CYGPVRVSLYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSR 352 Query: 368 YFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLV 427 F A YL+Y+ FT+ ++P L Q + + T + + L+ Sbjct: 353 -FFFNFACYLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLL 396 Query: 428 GELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISA 487 G ++ ++G I +LL ++ +R + F + + F +L + A + +++ V+R + Sbjct: 397 GHILILLGGIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMET 454 Query: 488 SGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASA 547 + + +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 455 EWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVA 514 Query: 548 FYIIFQTEDPEELGHFYD-----------------YPMALFSTFELF-LTIIDGPANYNV 589 + + + + Y L ++ ELF TI G + Sbjct: 515 LVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQE 574 Query: 590 DLPFMY--SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERK 647 L F + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 575 QLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENG 634 Query: 648 LPRCLWP--RSG----ICGREYGLGD-RWFLRVED 675 C R G + R G D RW RVE+ Sbjct: 635 YWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 669 >6MHW-A nrPDB Length = 826 Score = 544 bits (1401), Expect = e-155, Method: Composition-based stats. Identities = 174/595 (29%), Positives = 294/595 (49%), Gaps = 54/595 (9%) Query: 114 QRGAMGETALHIAALY---DNLEAAMVLMEAAPE------LVFEPMTSELYEGQTALHIA 164 G+T L A L + E +L+ A E + T E YEGQTAL+IA Sbjct: 164 TASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIA 223 Query: 165 VVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 + + ++ L+A A V+A A G F + YFGE PL+ AAC N EIV+LL+ Sbjct: 224 IERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLM 283 Query: 224 EH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPN 277 EH DI ++DS GN +LH L+ + F +MY+++L + L+ N Sbjct: 284 EHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGN----WELETTRN 339 Query: 278 HQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHTQWTYGPLTSTLYDLTEIDSS 326 + GLTP +LA G + ++++ + RK T W YGP++S+LYDLT +D++ Sbjct: 340 NDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTT 399 Query: 327 GDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTM 385 D S+LE+ + + R ++L P+ L+ +KWK++ + F + Y Y I T+ Sbjct: 400 TD-NSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTL 458 Query: 386 CCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVP 445 YRP R+ + L M ++L+G + +I A+ I + E Sbjct: 459 VSYYRP-----------REEEAIPHPLALTHKMGW---LQLLGRMFVLIWAMCISVKEGI 504 Query: 446 DIFRMGVTRFFGQTIL-GGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCN 504 IF + + Q+IL FH + A +V++++ + L + + + A+ LGW N Sbjct: 505 AIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWAN 562 Query: 505 VMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQ--TEDPEELGH 562 ++Y+ RGFQ +G +++MIQK+I D+++F ++ V +LGF A + + +D ++ Sbjct: 563 MLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSS 622 Query: 563 FYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTH 622 + + A+ F+L + + D N P ++ + I+ +L+LN+LIA+MG+T Sbjct: 623 YGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETV 682 Query: 623 WRVAHERDELWRAQIVATTVMLERKLPRCLWPRSGICGREYGLGD--RWFLRVED 675 V+ E + +WR Q T + E+ LP L R + D R LR+ + Sbjct: 683 ENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINE 737 >2RFA-A nrPDB Length = 232 Score = 296 bits (759), Expect = 2e-80, Method: Composition-based stats. Identities = 198/221 (89%), Positives = 209/221 (94%), Gaps = 1/221 (0%) Query: 84 IWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 143 IWESPLLLAAK+NDVQAL+KLLK+E C+VHQRGAMGETALHIAALYDNLEAAMVLMEAAP Sbjct: 2 IWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 61 Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFG 203 ELVFEPMTSELYEGQTALHIAV+NQN+NLVRALLAR ASVSARATG+ F P NLIY+G Sbjct: 62 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 121 Query: 204 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 EHPLSFAACV SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD Sbjct: 122 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 GDHL+ L+LVPN+QGLTPFKLAGVEGN VMFQHLMQKRK Sbjct: 182 G-GDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 221 >2ETB-A nrPDB Length = 256 Score = 224 bits (571), Expect = 1e-58, Method: Composition-based stats. Identities = 78/225 (34%), Positives = 112/225 (49%), Gaps = 17/225 (7%) Query: 96 NDVQALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LV 146 ++ L KY + G+ G+T L A L D + A M L++ + LV Sbjct: 20 GLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLV 79 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 T E Y+G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE P Sbjct: 80 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 139 Query: 207 LSFAACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNL 258 LS AAC ++V L+E+ A + A DSLGNTVLH L++ N MY+ Sbjct: 140 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 199 Query: 259 LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 LL L+ + NHQGLTP KLA EG +F+H++Q+ Sbjct: 200 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 244 >2F37-A nrPDB Length = 251 Score = 221 bits (563), Expect = 1e-57, Method: Composition-based stats. Identities = 75/222 (33%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 99 QALNKLLKYEDCKVHQRGAMGETALHIAAL--YDNLEAAMV-LMEAAPE------LVFEP 149 + L+K KY + G+ G+T L A L D + A ++ L++ + LV Sbjct: 28 EYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQ 87 Query: 150 MTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSF 209 T + Y G +ALHIA+ +++ V+ L+ A+V ARA G F++ YFGE PLS Sbjct: 88 CTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSL 147 Query: 210 AACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLS 261 AAC ++V L+E+ A ++A DS GNTVLH L++ N MY+ LL Sbjct: 148 AACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQ 207 Query: 262 YDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 L+ + N Q LTP KLA EG +F+H++Q+ Sbjct: 208 AGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQRE 249 >3W9G-A nrPDB Length = 260 Score = 206 bits (523), Expect = 4e-53, Method: Composition-based stats. Identities = 74/229 (32%), Positives = 109/229 (47%), Gaps = 18/229 (7%) Query: 93 AKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALY---DNLEAAMVLMEAAP------ 143 + + L K + + + G+T L A L + +L++ A Sbjct: 20 GLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRNDTIPILLDIAEKTGNMR 79 Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 202 E + P Y GQTALHIA+ + + V L+ + A V A+A G F+ + YF Sbjct: 80 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 139 Query: 203 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC N IV L E+G AD+R QDS GNTVLH L+ + N F + Sbjct: 140 GELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTK 199 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 MY+LLL L+ + N+ GL+P +A G +FQH++++ Sbjct: 200 MYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRRE 248 >4DX2-A nrPDB Length = 259 Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats. Identities = 78/230 (33%), Positives = 110/230 (47%), Gaps = 18/230 (7%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALY---DNLEAAMVLMEAAP----- 143 A D + L K + + + G+T L A L + VL++ A Sbjct: 17 ADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNM 76 Query: 144 -ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIY 201 E + P Y GQTALHIA+ + + V L+A+ A V A+A G F+ + Y Sbjct: 77 REFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFY 136 Query: 202 FGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFAC 253 FGE PLS AAC N IV L E+ AD+R QDS GNTVLH L+ + N F Sbjct: 137 FGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVT 196 Query: 254 QMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 +MY+LLL L+ V N+ GL+P +A G +FQH++++ Sbjct: 197 KMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRRE 246 >2NYJ-A nrPDB Length = 273 Score = 189 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 77/248 (31%), Positives = 117/248 (47%), Gaps = 20/248 (8%) Query: 78 LLQQKRIWESPLLLAAKDND--VQALNKLLKYEDCKVHQRGAMGETALHIAALY---DNL 132 L ++ I+++ ++ + + L + K + G+T L A L Sbjct: 11 LYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQN 70 Query: 133 EAAMVLMEAA------PELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSAR 186 + +L++ A + V T Y+GQTALHIA+ +NM LV L+ A V A Sbjct: 71 DTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAA 130 Query: 187 ATGTAFRRSPCN-LIYFGEHPLSFAACVNSEEIVRLLIEH---GADIRAQDSLGNTVLHI 242 A G F+++ YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH Sbjct: 131 ANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHA 190 Query: 243 LILQP-----NKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQ 297 L+ N F MYN +L L+ + N +GLTP LA G + Sbjct: 191 LVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLA 250 Query: 298 HLMQKRKH 305 +++Q+ H Sbjct: 251 YILQREIH 258 >4N5Q-A nrPDB Length = 257 Score = 189 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 72/246 (29%), Positives = 113/246 (45%), Gaps = 35/246 (14%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVH---------------QRGAMGETALHIAALY---D 130 + A + V+ L +LL+ G+T L A L + Sbjct: 7 IFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPN 66 Query: 131 NLEAAMVLMEAAPE------LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS 184 E +L+ A E + T E YEGQTAL+IA+ + ++ L+A A V+ Sbjct: 67 TKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVN 126 Query: 185 ARATGTAFR-RSPCNLIYFGEHPLSFAACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHI 242 A A G F + YFGE PL+ AAC N EIV+LL+E+ DI +QDS GN +LH Sbjct: 127 AHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHA 186 Query: 243 LI-----LQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQ 297 L+ + F +MY+++L + L+ + N+ GLTP +LA G + + Sbjct: 187 LVTVAEDFKTQNDFVKRMYDMILLRSGN----WELETMRNNDGLTPLQLAAKMGKAEILK 242 Query: 298 HLMQKR 303 +++ + Sbjct: 243 YILSRE 248 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 7/150 (4%) Query: 77 NLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM 136 N+ ++R + +L A DV A K + + H+ GET L +AA + E Sbjct: 104 NIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQ 163 Query: 137 VLMEAAPELVFEPMTSELYEGQTALH-IAVVNQNMNLVRALLARRASVSARATGTAFRRS 195 +LME +TS+ G LH + V ++ + R + +G + Sbjct: 164 LLMEN----EQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELET 219 Query: 196 PCNLIYFGEHPLSFAACVNSEEIVRLLIEH 225 N G PL AA + EI++ ++ Sbjct: 220 MRNND--GLTPLQLAAKMGKAEILKYILSR 247 >6AUN-A nrPDB Length = 752 Score = 189 bits (479), Expect = 5e-48, Method: Composition-based stats. Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 39/235 (16%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LA + D + L +L++Y ++ GETA H A DN + +L + A Sbjct: 154 TPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNAS--- 210 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA-------TGTAFRRSPCNL 199 + +G T LH+A +VR LL A + T F + C Sbjct: 211 -AGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAE 269 Query: 200 IY--------------FGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILIL 245 + +G PL +A + E+ R+L++ G D+ + + GNT LH+ ++ Sbjct: 270 MIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALHVAVM 326 Query: 246 QPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLM 300 + F C M +LL+Y + P G TP LA + N M + L+ Sbjct: 327 R--NRFDCVM--VLLTYGANAG-------TPGEHGNTPLHLAISKDNMEMIKALI 370 Score = 86.7 bits (213), Expect = 4e-17, Method: Composition-based stats. Identities = 46/215 (21%), Positives = 79/215 (36%), Gaps = 32/215 (14%) Query: 78 LLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMV 137 L Q + +PL LA + + + ++L + + + G G +H A + A + Sbjct: 213 LNQVNKQGLTPLHLACQMGKQEMV-RVLLLCNARCNVMGPSGF-PIHTAMKFSQKGCAEM 270 Query: 138 LMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPC 197 ++ + + G + LH A +N + R LL R V + + Sbjct: 271 IISMDSSQIHS---KDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAA-------- 316 Query: 198 NLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYN 257 G L A N + V +L+ +GA+ GNT LH+ I + N +M Sbjct: 317 -----GNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDN----MEMIK 367 Query: 258 LLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGN 292 L+ + D PN G TP +A Sbjct: 368 ALIVFGAEVD-------TPNDFGETPAFMASKISK 395 Score = 82.0 bits (201), Expect = 8e-16, Method: Composition-based stats. Identities = 51/256 (19%), Positives = 92/256 (35%), Gaps = 32/256 (12%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAM-GETALHIAALYDNLEAAMVLMEAAPELV 146 P+ A K + ++ + ++H + G + LH A N E A +L++ ++ Sbjct: 255 PIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVD 311 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 G TALH+AV+ + V LL A+ G P Sbjct: 312 STSAA-----GNTALHVAVMRNRFDCVMVLLTYGAN-------------AGTPGEHGNTP 353 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L A ++ E+++ LI GA++ + G T + + Q+ + L+ R Sbjct: 354 LHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMA-----SKISKQLQD-LMPISRAR 407 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSS 326 L + + + + L G ++Q + G T L+D S+ Sbjct: 408 KPAFILSSMRDEKRIHDHLLCLDGGGVKGL-VIIQLLIAIEKASGVATKDLFDWVAGTST 466 Query: 327 GDEQSLLELIITTKKR 342 G +L L I K Sbjct: 467 G---GILALAILHSKS 479 >6MWQ-A nrPDB Length = 493 Score = 181 bits (458), Expect = 1e-45, Method: Composition-based stats. Identities = 53/177 (29%), Positives = 77/177 (43%), Gaps = 19/177 (10%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 9 LLEAARAGQDDEV-RILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV--- 64 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + GQT LH+A ++ +V LL A V+A G+ PL Sbjct: 65 --NAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALD-------------LIGKTPLH 109 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRH 265 A EIV +L++HGAD+ AQD G T I I N+ A + L LS H Sbjct: 110 LTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDIAH 166 Score = 117 bits (293), Expect = 2e-26, Method: Composition-based stats. Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 30/170 (17%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR L+A A V+A FG PL AA EIV +L+ Sbjct: 12 AARAGQDDEVRILMANGADVNALDR-------------FGLTPLHLAAQRGHLEIVEVLL 58 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 + GAD+ A D G T LH+ + ++ +LL Y G + LDL+ G TP Sbjct: 59 KCGADVNAADLWGQTPLHLAATAGH----LEIVEVLLKY---GADVNALDLI----GKTP 107 Query: 284 FKLAGVEGNTVMFQHLMQKRK--HTQWTYGPLTSTLYDLTEIDSSGDEQS 331 L ++G+ + + L++ + Q +G T +D++ ID+ ++ + Sbjct: 108 LHLTAIDGHLEIVEVLLKHGADVNAQDKFGK---TAFDIS-IDNGNEDLA 153 Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 12/127 (9%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ A D G T LH+ + + ++ +LL + G Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGH----LEIVEVLL---KCG 61 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSS 326 + DL G TP LA G+ + + L++ + T LT ID Sbjct: 62 ADVNAADL----WGQTPLHLAATAGHLEIVEVLLKYGADVN-ALDLIGKTPLHLTAIDGH 116 Query: 327 GDEQSLL 333 + +L Sbjct: 117 LEIVEVL 123 >5AQ9-A nrPDB Length = 422 Score = 180 bits (456), Expect = 2e-45, Method: Composition-based stats. Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 20/189 (10%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 18 LLEAARAGQDDEV-RILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV--- 73 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A ++ +V LL A V+A + G PL Sbjct: 74 --DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTPLH 118 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 268 AA EIV +L++HGAD+ AQD G T + N + + + D+ G Sbjct: 119 LAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGT-LLQVAAAADQLGAR 177 Query: 269 LQPLDLVPN 277 + ++L N Sbjct: 178 VGYIELDLN 186 Score = 121 bits (303), Expect = 1e-27, Method: Composition-based stats. Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 20/143 (13%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA ++ + LLK+ V G T LH+AA + +LE VL++ ++ Sbjct: 49 TPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADV- 106 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + +G T LH+A + +V LL A V+A+ FG+ P Sbjct: 107 ----NAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDK-------------FGKTP 149 Query: 207 LSFAACVNSEEIVRLL-IEHGAD 228 A ++++ LL + AD Sbjct: 150 FDLADDNGNDDVGTLLQVAAAAD 172 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 48/184 (26%), Positives = 79/184 (42%), Gaps = 29/184 (15%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR L+A A V+A G PL AA EIV +L+ Sbjct: 21 AARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVEVLL 67 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD+ A D G T LH+ + ++ +LL ++G + +D G+TP Sbjct: 68 KHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLL---KNGADVNAMDS----DGMTP 116 Query: 284 FKLAGVEGNTVMFQHLMQKRK--HTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKK 341 LA G + + L++ + Q +G T +DL + + + D +LL++ + Sbjct: 117 LHLAAKWGYLEIVEVLLKHGADVNAQDKFGK---TPFDLADDNGNDDVGTLLQVAAAADQ 173 Query: 342 REAR 345 AR Sbjct: 174 LGAR 177 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 49/160 (30%), Gaps = 59/160 (36%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ A D Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAAD--------------------------------- 44 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQ----WTYGPLTSTLYDLTE 322 + G TP LA G+ + + L++ + Y PL Y Sbjct: 45 -----------NTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAY---- 89 Query: 323 IDSSGDEQSLLELIITT-KKREARQILDQTPVKELVSLKW 361 ++E+++ A TP+ ++ KW Sbjct: 90 ----WGHLEIVEVLLKNGADVNAMDSDGMTPLH--LAAKW 123 >5AQA-A nrPDB Length = 418 Score = 177 bits (449), Expect = 2e-44, Method: Composition-based stats. Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 19/168 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 18 LLEAARAGQDDEV-RILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV--- 73 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A ++ +V LL A V+A + G PL Sbjct: 74 --DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTPLH 118 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY 256 AA +EIV +L++ GAD+ AQD G L + Q + A ++ Sbjct: 119 LAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166 Score = 135 bits (339), Expect = 9e-32, Method: Composition-based stats. Identities = 49/188 (26%), Positives = 75/188 (39%), Gaps = 29/188 (15%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA + +LM ++ + G T LH+A + ++ +V LL A Sbjct: 18 LLEAARAGQDDEVRILMANGADV-----NAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 72 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V A FG PL AA EIV +L+++GAD+ A DS G T LH+ Sbjct: 73 VDASDV-------------FGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHL 119 Query: 243 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 K ++ +LL + G + D G P LA +G+ + L+ Sbjct: 120 AA----KWGYKEIVEVLL---KAGADVDAQDKF----GKRPLWLAADQGHAEIAAKLVAA 168 Query: 303 RKHTQWTY 310 R + Y Sbjct: 169 RLKARVGY 176 Score = 122 bits (305), Expect = 9e-28, Method: Composition-based stats. Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 19/138 (13%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA ++ + LLK+ V G T LH+AA + +LE VL++ ++ Sbjct: 49 TPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADV- 106 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + +G T LH+A +V LL A V A+ FG+ P Sbjct: 107 ----NAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVDAQDK-------------FGKRP 149 Query: 207 LSFAACVNSEEIVRLLIE 224 L AA EI L+ Sbjct: 150 LWLAADQGHAEIAAKLVA 167 Score = 107 bits (266), Expect = 2e-23, Method: Composition-based stats. Identities = 40/151 (26%), Positives = 62/151 (41%), Gaps = 26/151 (17%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR L+A A V+A G PL AA EIV +L+ Sbjct: 21 AARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVEVLL 67 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD+ A D G T LH+ + ++ +LL ++G + +D G+TP Sbjct: 68 KHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLL---KNGADVNAMDS----DGMTP 116 Query: 284 FKLAGVEGNTVMFQHLMQKRK--HTQWTYGP 312 LA G + + L++ Q +G Sbjct: 117 LHLAAKWGYKEIVEVLLKAGADVDAQDKFGK 147 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 141 +PL LAAK + + LLK V + G+ L +AA + E A L+ A Sbjct: 115 TPLHLAAKWGYKEIVEVLLKA-GADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 49/160 (30%), Gaps = 59/160 (36%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ A D Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAAD--------------------------------- 44 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQ----WTYGPLTSTLYDLTE 322 + G TP LA G+ + + L++ + Y PL Y Sbjct: 45 -----------NTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAY---- 89 Query: 323 IDSSGDEQSLLELIITT-KKREARQILDQTPVKELVSLKW 361 ++E+++ A TP+ ++ KW Sbjct: 90 ----WGHLEIVEVLLKNGADVNAMDSDGMTPLH--LAAKW 123 >5H76-A nrPDB Length = 201 Score = 176 bits (446), Expect = 4e-44, Method: Composition-based stats. Identities = 54/199 (27%), Positives = 84/199 (42%), Gaps = 26/199 (13%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ G T LH+AA +LE VL++ ++ Sbjct: 10 LLEAARAGQDDEV-RILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV--- 65 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A ++ +V LL A V+A + G PL Sbjct: 66 --DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTPLH 110 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM--YNLL----LSY 262 AA EIV +L++HGA + AQD G T I I N+ A + Y +L L+ Sbjct: 111 LAAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLAQILAFYEILHLPNLNE 169 Query: 263 DRHGDHLQPLDLVPNHQGL 281 ++ +Q L P+ Sbjct: 170 EQRNAFIQSLKDDPSQSAN 188 Score = 126 bits (316), Expect = 4e-29, Method: Composition-based stats. Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 30/177 (16%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA + +LM ++ + G T LH+A + ++ +V LL A Sbjct: 10 LLEAARAGQDDEVRILMANGADV-----NAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 64 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V A FG PL AA EIV +L+++GAD+ A DS G T LH+ Sbjct: 65 VDASDV-------------FGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHL 111 Query: 243 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHL 299 K ++ +LL +HG + D G T F ++ GN + Q L Sbjct: 112 AA----KWGYLEIVEVLL---KHGA-VNAQDKF----GKTAFDISIDNGNEDLAQIL 156 Score = 118 bits (295), Expect = 1e-26, Method: Composition-based stats. Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 37/193 (19%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR L+A A V+A G PL AA EIV +L+ Sbjct: 13 AARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVEVLL 59 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD+ A D G T LH+ + ++ +LL ++G + +D G+TP Sbjct: 60 KHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLL---KNGADVNAMDS----DGMTP 108 Query: 284 FKLAGVEGNTVMFQHLMQKRK-HTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKR 342 LA G + + L++ + Q +G T +D++ ID+ ++ L +++ Sbjct: 109 LHLAAKWGYLEIVEVLLKHGAVNAQDKFGK---TAFDIS-IDNGNED--LAQILAFY--- 159 Query: 343 EARQILDQTPVKE 355 +IL + E Sbjct: 160 ---EILHLPNLNE 169 Score = 110 bits (274), Expect = 3e-24, Method: Composition-based stats. Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 20/136 (14%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA ++ + LLK+ V G T LH+AA + +LE VL++ ++ Sbjct: 41 TPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADV- 98 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + +G T LH+A + +V LL A V+A+ FG+ Sbjct: 99 ----NAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VNAQDK-------------FGKTA 140 Query: 207 LSFAACVNSEEIVRLL 222 + +E++ ++L Sbjct: 141 FDISIDNGNEDLAQIL 156 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 49/160 (30%), Gaps = 59/160 (36%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ A D Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAAD--------------------------------- 36 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQ----WTYGPLTSTLYDLTE 322 + G TP LA G+ + + L++ + Y PL Y Sbjct: 37 -----------NTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAY---- 81 Query: 323 IDSSGDEQSLLELIITT-KKREARQILDQTPVKELVSLKW 361 ++E+++ A TP+ ++ KW Sbjct: 82 ----WGHLEIVEVLLKNGADVNAMDSDGMTPLH--LAAKW 115 >5AQB-A nrPDB Length = 428 Score = 173 bits (439), Expect = 2e-43, Method: Composition-based stats. Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 20/167 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ ++L V+ +G T LH+AA +LE L++ ++ Sbjct: 18 LLEAARAGQDDEC-RILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADV--- 72 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + +G T LH+A + ++ +V LL A V+A G PL Sbjct: 73 --NAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQA-------------GFTPLH 117 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 AA EIV +L+++GAD+ AQD G T + I N+ A + Sbjct: 118 LAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVL 164 Score = 125 bits (314), Expect = 7e-29, Method: Composition-based stats. Identities = 46/177 (25%), Positives = 72/177 (40%), Gaps = 30/177 (16%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA + +LM ++ + G T LH+A ++ +V LL A Sbjct: 18 LLEAARAGQDDECRILMANGADV-----NALDEVGWTPLHLAA-WGHLEIVECLLKNGAD 71 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V+A G PL AA EIV +L+++GAD+ A D G T LH+ Sbjct: 72 VNAAD-------------IDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHL 118 Query: 243 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHL 299 + + ++ +LL ++G + D G TP LA GN + + L Sbjct: 119 AAIFGH----LEIVEVLL---KNGADVNAQDKF----GKTPRDLAIDNGNEDIAEVL 164 Score = 105 bits (263), Expect = 6e-23, Method: Composition-based stats. Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 31/168 (18%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + R L+A A V+A G PL AA EIV L+ Sbjct: 21 AARAGQDDECRILMANGADVNALDE-------------VGWTPLHLAA-WGHLEIVECLL 66 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 ++GAD+ A D G T LH+ + ++ +LL Y G + D G TP Sbjct: 67 KNGADVNAADIDGYTPLHLAAFSGH----LEIVEVLLKY---GADVNADDQA----GFTP 115 Query: 284 FKLAGVEGNTVMFQHLMQKRK--HTQWTYGPLTSTLYDLTEIDSSGDE 329 LA + G+ + + L++ + Q +G T DL ID+ ++ Sbjct: 116 LHLAAIFGHLEIVEVLLKNGADVNAQDKFGK---TPRDLA-IDNGNED 159 Score = 88.6 bits (218), Expect = 8e-18, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 6/104 (5%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA ++ + LLKY V+ G T LH+AA++ +LE VL++ ++ Sbjct: 81 TPLHLAAFSGHLEIVEVLLKY-GADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADV- 138 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGT 190 ++ G+T +A+ N N ++ L V + Sbjct: 139 ----NAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAAD 178 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 16/115 (13%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ R+L+ +GAD+ A D +G T LH+ ++ LL ++G Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAA-----WGHLEIVECLL---KNG 69 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHT----QWTYGPLTSTL 317 + D+ G TP LA G+ + + L++ Q + PL Sbjct: 70 ADVNAADI----DGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAA 120 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA ++ + LLK V+ + G+T +A N + A VL +AA + Sbjct: 114 TPLHLAAIFGHLEIVEVLLK-NGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVK 172 Query: 147 FEPMTSEL 154 + +L Sbjct: 173 VKDAADQL 180 >5AQ7-A nrPDB Length = 418 Score = 173 bits (439), Expect = 2e-43, Method: Composition-based stats. Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 19/168 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ G T LH+AA +L VL++ ++ Sbjct: 18 LLEAARAGQDDEV-RILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV--- 73 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A ++ +V LL A V+A G PL Sbjct: 74 --NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLH 118 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY 256 AA +EIV +L++ GAD+ AQD G L + Q + A ++ Sbjct: 119 LAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166 Score = 123 bits (308), Expect = 3e-28, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 72/188 (38%), Gaps = 29/188 (15%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA + +L+ ++ + G T LH+A ++ +V LL A Sbjct: 18 LLEAARAGQDDEVRILLANGADV-----NTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 72 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V+A G PL AA EIV +L+++GA + A D +G LH+ Sbjct: 73 VNANDER-------------GHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHL 119 Query: 243 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 + ++ +LL + G + D G P LA +G+ + L+ Sbjct: 120 AAM----WGYKEIVEVLL---KAGADVDAQDKF----GKRPLWLAADQGHAEIAAKLVAA 168 Query: 303 RKHTQWTY 310 R + Y Sbjct: 169 RLKARVGY 176 Score = 116 bits (291), Expect = 3e-26, Method: Composition-based stats. Identities = 38/138 (27%), Positives = 55/138 (39%), Gaps = 19/138 (13%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA + + + LLK V+ G T LH+AA +LE VL++ + Sbjct: 49 TPLHLAAWEGHLGIVEVLLK-NGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGV- 106 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + G LH+A + +V LL A V A+ FG+ P Sbjct: 107 ----NATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVDAQDK-------------FGKRP 149 Query: 207 LSFAACVNSEEIVRLLIE 224 L AA EI L+ Sbjct: 150 LWLAADQGHAEIAAKLVA 167 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 37/151 (24%), Positives = 61/151 (40%), Gaps = 26/151 (17%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR LLA A V+ G PL AA IV +L+ Sbjct: 21 AARAGQDDEVRILLANGADVNTADET-------------GFTPLHLAAWEGHLGIVEVLL 67 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 ++GAD+ A D G+T LH+ + ++ +LL ++G + D++ G P Sbjct: 68 KNGADVNANDERGHTPLHLAAYTGH----LEIVEVLL---KNGAGVNATDVI----GTAP 116 Query: 284 FKLAGVEGNTVMFQHLMQKRK--HTQWTYGP 312 LA + G + + L++ Q +G Sbjct: 117 LHLAAMWGYKEIVEVLLKAGADVDAQDKFGK 147 Score = 43.5 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Query: 84 IWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 141 I +PL LAA + + LLK V + G+ L +AA + E A L+ A Sbjct: 112 IGTAPLHLAAMWGYKEIVEVLLKA-GADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 35.8 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 34/116 (29%), Gaps = 48/116 (41%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ D Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTAD--------------------------------- 44 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK--HTQWTYG--PLTSTLY 318 G TP LA EG+ + + L++ + G PL Y Sbjct: 45 -----------ETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAY 89 >6G1K-A nrPDB Length = 921 Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats. Identities = 101/656 (15%), Positives = 206/656 (31%), Gaps = 102/656 (15%) Query: 63 FQRRESWAQSRDEQNLL-----QQKRIWESPLLLAAKDNDVQALNKLLK----YEDCKVH 113 + RR + RD L + E L A + D ++ L+ Y ++ Sbjct: 5 YFRRTDNSSYRDRIPLRIVRAESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININ 64 Query: 114 QRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLV 173 +G TAL IA +NLE +L+ Y G LH A+ + + V Sbjct: 65 CIDPLGRTALLIAIENENLEIIELLLSFNV-----------YVGDALLH-AIRKEVVGAV 112 Query: 174 RALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQD 233 LL + + + P+ AA N+ EI+++L++ G + Sbjct: 113 ELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPH 172 Query: 234 SLGNTVLHILILQP-----NKTFACQMYNLLLS--YDRHGDHLQPLDLVPNHQGLTPFKL 286 + + + + +Y L S L L Sbjct: 173 EVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSK 232 Query: 287 AGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK------ 340 E + Q + + S+ +L I + D+ +LL+ + Sbjct: 233 VENEFKAEYEELSHQCKHFAKDLLDQTRSS-RELELILNFRDDMNLLQDEANNELARLKL 291 Query: 341 --KREARQILDQTPVKELVSLKWKR------------------YGRPYFCMLGAIYLLY- 379 K ++ + Q ++L++ +W + F +L YL+ Sbjct: 292 AIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAP 351 Query: 380 -----IIC----FTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGEL 430 + C + + Q T + + Sbjct: 352 KSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSNNPDRQGPKPTTVEWM------ 405 Query: 431 VTVIGAIIILLVEVPDIFRMGVTRFF--GQTILGGPFHVLIITYAFMVLVTMVMR----- 483 + + + E+ ++ G + ++ + L + + +V V Sbjct: 406 -ILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCKP 464 Query: 484 LISASGEVVPMSFALVLGWCNVMYFAR------GFQMLGPFTIMIQKMIFGDLMRFCWLM 537 + + V N+ R LGP I + +M+ D+++F ++ Sbjct: 465 RDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL-DILKFLFIY 523 Query: 538 AVVILGFASAF-YIIFQTEDPEE-------LGHFYDYPMALFSTFELFLTIIDGPANYNV 589 +V+L FA+ + F E+ E + LF T + I G + V Sbjct: 524 CLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNAFSTLFETLQSLFWSIFGLISLYV 583 Query: 590 D--------LPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQI 637 F+ + + + +I+ +++LN+LIAMM +++ +A D W+ Sbjct: 584 TNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFAR 639 >5MIO-C nrPDB Length = 573 Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats. Identities = 51/172 (29%), Positives = 79/172 (45%), Gaps = 19/172 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ A G T LH+AA Y +LE VL++ ++ Sbjct: 414 LLEAARAGQDDEV-RVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSAS 472 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A + ++ +V LL A V+A T +G+ PL Sbjct: 473 DLM-----GSTPLHLAALIGHLEIVEVLLKHGADVNAVDT-------------WGDTPLR 514 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 260 AA + +IV L++HGAD+ AQD G T I ++ A + L L Sbjct: 515 LAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQKLNL 566 Score = 127 bits (318), Expect = 2e-29, Method: Composition-based stats. Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 30/170 (17%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR L+A A V+A G PL AA EIV +L+ Sbjct: 417 AARAGQDDEVRVLMANGADVNATDAS-------------GLTPLHLAATYGHLEIVEVLL 463 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD+ A D +G+T LH+ L + ++ +LL +HG + +D G TP Sbjct: 464 KHGADVSASDLMGSTPLHLAALIGH----LEIVEVLL---KHGADVNAVDT----WGDTP 512 Query: 284 FKLAGVEGNTVMFQHLMQKRK--HTQWTYGPLTSTLYDLTEIDSSGDEQS 331 +LA V G+ + + L++ + Q +G T YD T ID+ ++ + Sbjct: 513 LRLAAVMGHLKIVEALLKHGADVNAQDKFGK---TAYD-TSIDNGSEDLA 558 Score = 37.4 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 ++PL LAA ++ + LLK+ V+ + G+TA + + + A +L + E Sbjct: 510 DTPLRLAAVMGHLKIVEALLKH-GADVNAQDKFGKTAYDTSIDNGSEDLAEILQKLNLE 567 >2DWZ-A nrPDB Length = 231 Score = 169 bits (428), Expect = 4e-42, Method: Composition-based stats. Identities = 57/245 (23%), Positives = 96/245 (39%), Gaps = 32/245 (13%) Query: 93 AKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTS 152 A + L + + + + TALH A + E L++ P+ Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV-----PVND 68 Query: 153 ELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAAC 212 + G + LHIA +V+ALL + A V+A G PL +AA Sbjct: 69 KDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQN-------------GCTPLHYAAS 115 Query: 213 VNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGD----- 267 N EI +L+E GA+ A+D T +H + N +M ++LL Y + Sbjct: 116 KNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGN----LKMVHILLFYKASTNIQDTE 171 Query: 268 HLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSG 327 PL L + + + K +G ++ ++ +++ Q G L L L E G Sbjct: 172 GNTPLHLACDEERVEEAKFLVTQGASIYIEN-KEEKTPLQVAKGGLGLILKRLAE----G 226 Query: 328 DEQSL 332 +E S+ Sbjct: 227 EEASM 231 Score = 137 bits (345), Expect = 2e-32, Method: Composition-based stats. Identities = 42/157 (26%), Positives = 64/157 (40%), Gaps = 19/157 (12%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SPL +AA + + LL + V+ G T LH AA + E A++L+E Sbjct: 75 SPLHIAASAGRDEIVKALL-VKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA--- 130 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 P + Y+ TA+H A N+ +V LL +AS + + T G P Sbjct: 131 -NPDAKDHYDA-TAMHRAAAKGNLKMVHILLFYKASTNIQDTE-------------GNTP 175 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 L A E + L+ GA I ++ T L + Sbjct: 176 LHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVA 212 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%), Gaps = 1/46 (2%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIA 126 Q +PL LA + V+ L+ + ++ +T L +A Sbjct: 168 QDTEGNTPLHLACDEERVEEAKFLVT-QGASIYIENKEEKTPLQVA 212 >6FES-A nrPDB Length = 367 Score = 168 bits (426), Expect = 7e-42, Method: Composition-based stats. Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 19/164 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + ++L V+ G T LH+AA +L VL++ ++ Sbjct: 10 LLEAARAGQDDEV-RILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV--- 65 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A ++ +V LL A V+A G PL Sbjct: 66 --NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLH 110 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 252 AA EEIV +L+++GAD RAQD G T + ++ A Sbjct: 111 LAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVA 154 Score = 112 bits (279), Expect = 7e-25, Method: Composition-based stats. Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 19/135 (14%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA + + + LLK V+ G T LH+AA +LE VL++ + Sbjct: 41 TPLHLAAWEGHLGIVEVLLK-NGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGV- 98 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + G LH+A + + +V LL A A+ FG+ P Sbjct: 99 ----NATDVIGTAPLHLAAMWGHEEIVEVLLKNGADARAQDK-------------FGKTP 141 Query: 207 LSFAACVNSEEIVRL 221 A E + RL Sbjct: 142 EDLARDNGYESVARL 156 Score = 100 bits (249), Expect = 2e-21, Method: Composition-based stats. Identities = 40/172 (23%), Positives = 68/172 (39%), Gaps = 30/172 (17%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + VR LLA A V+ G PL AA IV +L+ Sbjct: 13 AARAGQDDEVRILLANGADVNTADET-------------GFTPLHLAAWEGHLGIVEVLL 59 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 ++GAD+ A D G+T LH+ + ++ +LL ++G + D++ G P Sbjct: 60 KNGADVNANDERGHTPLHLAAYTGH----LEIVEVLL---KNGAGVNATDVI----GTAP 108 Query: 284 FKLAGVEGNTVMFQHLMQKRKH--TQWTYGPLTSTLYDLTEIDSSGDEQSLL 333 LA + G+ + + L++ Q +G L D+ + + L Sbjct: 109 LHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLAR----DNGYESVARL 156 Score = 65.5 bits (158), Expect = 9e-11, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 11/98 (11%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ D G T LH+ + + + +LL ++G Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGH----LGIVEVLL---KNG 62 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 + + +G TP LA G+ + + L++ Sbjct: 63 ADVNA----NDERGHTPLHLAAYTGHLEIVEVLLKNGA 96 Score = 35.8 bits (81), Expect = 0.076, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 20/54 (37%), Gaps = 1/54 (1%) Query: 84 IWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMV 137 I +PL LAA + + LLK + G+T +A A + Sbjct: 104 IGTAPLHLAAMWGHEEIVEVLLK-NGADARAQDKFGKTPEDLARDNGYESVARL 156 >4NIK-A nrPDB Length = 230 Score = 163 bits (412), Expect = 3e-40, Method: Composition-based stats. Identities = 54/235 (22%), Positives = 93/235 (39%), Gaps = 28/235 (11%) Query: 93 AKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTS 152 A ++ L + + + + TALH A + E L++ P+ Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV-----PVND 72 Query: 153 ELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAAC 212 + G + LHIA +V+ALL + A V+A G PL +AA Sbjct: 73 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTPLHYAAS 119 Query: 213 VNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGD----- 267 N EI +L+E GA+ A+D T +H + N +M ++LL Y + Sbjct: 120 KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGN----LKMIHILLYYKASTNIQDTE 175 Query: 268 HLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTE 322 PL L + + + KL +G ++ ++ +++ Q G L L + E Sbjct: 176 GNTPLHLACDEERVEEAKLLVSQGASIYIEN-KEEKTPLQVAKGGLGLILKRMVE 229 Score = 141 bits (356), Expect = 9e-34, Method: Composition-based stats. Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 19/157 (12%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SPL +AA + + LL + +V+ G T LH AA + E A++L+E Sbjct: 79 SPLHIAASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA--- 134 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 P + YE TA+H A N+ ++ LL +AS + + T G P Sbjct: 135 -NPDAKDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTE-------------GNTP 179 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 L A E +LL+ GA I ++ T L + Sbjct: 180 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 216 Score = 33.1 bits (74), Expect = 0.44, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIA 126 Q +PL LA + V+ KLL + ++ +T L +A Sbjct: 172 QDTEGNTPLHLACDEERVEE-AKLLVSQGASIYIENKEEKTPLQVA 216 >5Z96-A nrPDB Length = 755 Score = 162 bits (410), Expect = 5e-40, Method: Composition-based stats. Identities = 116/732 (15%), Positives = 235/732 (32%), Gaps = 124/732 (16%) Query: 59 FCRWFQRRESWAQSRDEQNLL-----QQKRIWESPLLLAAKDNDVQALNKLLK----YED 109 +++ +R A RD L + E L A + D ++ K L+ Y Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60 Query: 110 CKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQN 169 ++ +G TAL IA EL+ ++ +Y G LH A+ + Sbjct: 61 ININCIDPLGRTALLIAIEN-----------ENLELIELLLSFNVYVGDALLH-AIRKEV 108 Query: 170 MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADI 229 + V LL + + + P+ AA N+ EI++LL++ G + Sbjct: 109 VGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSV 168 Query: 230 RAQDSLGNTVLHILILQP-----NKTFACQMYNLLLS--YDRHGDHLQPLDLVPNHQGLT 282 + + + + +Y L S L L Sbjct: 169 PRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQ 228 Query: 283 PFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK-- 340 E + + Q ++ + S+ +L I + D+ SL+E Sbjct: 229 ELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSS-RELEIILNYRDDNSLIEEQSGNDLA 287 Query: 341 ------KREARQILDQTPVKELVSLKW-KRY-----------------GRPYFCMLGAIY 376 K ++ + Q ++L++ +W + F + Y Sbjct: 288 RLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCY 347 Query: 377 LLY---------------IICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPK 421 L+ IC T Y + D + L ++ + Sbjct: 348 LIAPKSPLGLFIRKPFIKFICHT--ASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWM 405 Query: 422 DDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFF--GQTILGGPFHVLIITYAFMVLVT 479 + + + E+ ++ G+ + ++ + L + + +V Sbjct: 406 ----------ILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVA 455 Query: 480 MVMRLI-----SASGEVVPMSFALVLGWCNVMYFAR------GFQMLGPFTIMIQKMIFG 528 V S + + N+ R LGP I + +M+ Sbjct: 456 FVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL- 514 Query: 529 DLMRFCWLMAVVILGFASAF-YIIFQTEDPEELG-------HFYDYPMALFSTFELFLTI 580 D+++F ++ +V+L FA+ + F E+ + L + LF T + Sbjct: 515 DILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETLQSLFWS 574 Query: 581 IDGPANYNVD--------LPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDEL 632 I G N V F+ + + + +I+ +++LN+LIAMM +++ +A D Sbjct: 575 IFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIE 634 Query: 633 WRAQIVATTVMLERKLPRCLWPRSGICGREYGL----GDRWFLRVEDRQDLNRQRIQRYA 688 W+ KL + G + + W+L L +++++R Sbjct: 635 WKFART--------KLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMRRKP 686 Query: 689 QAFHTRGSEDLD 700 ++F T G D Sbjct: 687 ESFGTIGRRAAD 698 >6BY9-A nrPDB Length = 328 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 54/224 (24%), Positives = 87/224 (38%), Gaps = 34/224 (15%) Query: 80 QQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM 139 Q KR SPL AA+ V + L++ + T L AA ++LEA L+ Sbjct: 100 QNKR---SPLHAAAEAGHVDICHMLVQA-GANIDTCSEDQRTPLMEAAENNHLEAVKYLI 155 Query: 140 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARR-ASVSARATGTAFRRSPCN 198 +A + +P +E G T LH+A + +V+ LL+ V+ + G Sbjct: 156 KAGA--LVDPKDAE---GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG--------- 201 Query: 199 LIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL 258 G P+ +A ++V+LL+ G+DI +D+ N LH A + Sbjct: 202 ----GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA----EI 253 Query: 259 LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 LL L V N G +P +A E + + Sbjct: 254 LL------AAKCDLHAV-NIHGDSPLHIAARENRYDCVVLFLSR 290 Score = 119 bits (298), Expect = 5e-27, Method: Composition-based stats. Identities = 44/193 (22%), Positives = 78/193 (40%), Gaps = 25/193 (12%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL+ AA++N ++A+ L+K V + A G T LH+AA + E L+ Sbjct: 137 TPLMEAAENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG---- 191 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGT---------------- 190 + + G T + A ++++LV+ LL++ + ++ R Sbjct: 192 QMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA 251 Query: 191 ----AFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 246 A + + G+ PL AA N + V L + +D+ ++ G T L L Sbjct: 252 EILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLN 311 Query: 247 PNKTFACQMYNLL 259 A QM L Sbjct: 312 SQVWSALQMSKAL 324 Score = 79.7 bits (195), Expect = 4e-15, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 68/182 (37%), Gaps = 26/182 (14%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L+ +A L+ ++++ + + E ++ LH A ++++ L+ A+ Sbjct: 71 LYFSARQGELQKVLLML---VDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGAN 127 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 + PL AA N E V+ LI+ GA + +D+ G+T LH+ Sbjct: 128 ID-------------TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHL 174 Query: 243 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 + + Y ++ +G + G TP A + + + L+ K Sbjct: 175 AAKKGH-------YEVVQYLLSNGQMDVNCQ---DDGGWTPMIWATEYKHVDLVKLLLSK 224 Query: 303 RK 304 Sbjct: 225 GS 226 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +SPL +AA++N L D V + GET L A+L + +A+ + +A + Sbjct: 269 DSPLHIAARENRYD-CVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQD 326 >3B7B-A nrPDB Length = 237 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 54/224 (24%), Positives = 87/224 (38%), Gaps = 34/224 (15%) Query: 80 QQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM 139 Q KR SPL AA+ V + L++ + T L AA ++LEA L+ Sbjct: 9 QNKR---SPLHAAAEAGHVDICHMLVQA-GANIDTCSEDQRTPLMEAAENNHLEAVKYLI 64 Query: 140 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARR-ASVSARATGTAFRRSPCN 198 +A + +P +E G T LH+A + +V+ LL+ V+ + G Sbjct: 65 KAGA--LVDPKDAE---GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG--------- 110 Query: 199 LIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL 258 G P+ +A ++V+LL+ G+DI +D+ N LH A + Sbjct: 111 ----GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA----EI 162 Query: 259 LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 LL L V N G +P +A E + + Sbjct: 163 LL------AAKCDLHAV-NIHGDSPLHIAARENRYDCVVLFLSR 199 Score = 119 bits (298), Expect = 5e-27, Method: Composition-based stats. Identities = 44/193 (22%), Positives = 78/193 (40%), Gaps = 25/193 (12%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL+ AA++N ++A+ L+K V + A G T LH+AA + E L+ Sbjct: 46 TPLMEAAENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG---- 100 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGT---------------- 190 + + G T + A ++++LV+ LL++ + ++ R Sbjct: 101 QMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA 160 Query: 191 ----AFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 246 A + + G+ PL AA N + V L + +D+ ++ G T L L Sbjct: 161 EILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLN 220 Query: 247 PNKTFACQMYNLL 259 A QM L Sbjct: 221 SQVWSALQMSKAL 233 Score = 75.1 bits (183), Expect = 1e-13, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 56/152 (36%), Gaps = 23/152 (15%) Query: 153 ELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAAC 212 E ++ LH A ++++ L+ A++ PL AA Sbjct: 7 EHQNKRSPLHAAAEAGHVDICHMLVQAGANID-------------TCSEDQRTPLMEAAE 53 Query: 213 VNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPL 272 N E V+ LI+ GA + +D+ G+T LH+ + + Y ++ +G Sbjct: 54 NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGH-------YEVVQYLLSNGQMDVNC 106 Query: 273 DLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 + G TP A + + + L+ K Sbjct: 107 Q---DDGGWTPMIWATEYKHVDLVKLLLSKGS 135 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +SPL +AA++N L D V + GET L A+L + +A+ + +A + Sbjct: 178 DSPLHIAARENRYD-CVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQD 235 >5GP7-A nrPDB Length = 169 Score = 150 bits (378), Expect = 2e-36, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 18/158 (11%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 ++ LL AAK + + KL E+ T LH+AA Y+NLE A L+E ++ Sbjct: 10 DAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADV 69 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 ++ G LH A ++++ L+ V+A Sbjct: 70 -----NAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAF-------------T 111 Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL AA ++ LL+ HGAD ++ G T L + Sbjct: 112 PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149 Score = 78.2 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 38/153 (24%), Positives = 56/153 (36%), Gaps = 23/153 (15%) Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 S+L G AL A + V+ L +++ R T PL AA Sbjct: 4 SDLLRGDAALLDAAKKGCLARVQKLCTPE-NINCRDTQGRNS-----------TPLHLAA 51 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQP 271 N+ E+ L+EHGAD+ AQD G LH + A LL+ Y+ + Sbjct: 52 GYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA----LLIKYNTCVN---- 103 Query: 272 LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 + TP A +G T + L+ Sbjct: 104 ---ATDKWAFTPLHEAAQKGRTQLCALLLAHGA 133 Score = 36.6 bits (83), Expect = 0.042, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL AA+ Q LL + G+T L +A D +L++A PE Sbjct: 111 TPLHEAAQKGRTQLC-ALLLAHGADPTMKNQEGQTPLDLATADD---IRALLIDAMPE 164 >4Z68-A nrPDB Length = 155 Score = 134 bits (337), Expect = 1e-31, Method: Composition-based stats. Identities = 42/174 (24%), Positives = 67/174 (38%), Gaps = 23/174 (13%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + LL AAK DV+ + KL + T LH AA Y+ + L++ ++ Sbjct: 4 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 ++ G LH A + + L+ A V+ Sbjct: 64 -----HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKF-------------T 105 Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLL 259 PL AA EI +LL++HGAD ++ GNT L ++ K + +LL Sbjct: 106 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-----KDGDTDIQDLL 154 Score = 76.7 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 33/141 (23%), Positives = 52/141 (36%), Gaps = 23/141 (16%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A ++ V+ L + SV+ R PL FAA N +V L+ Sbjct: 10 AAKAGDVETVKKLCTVQ-SVNCRDIEGRQS-----------TPLHFAAGYNRVSVVEYLL 57 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD+ A+D G LH + Y + +HG + V + TP Sbjct: 58 QHGADVHAKDKGGLVPLHNACSYGH-------YEVAELLVKHGAVVN----VADLWKFTP 106 Query: 284 FKLAGVEGNTVMFQHLMQKRK 304 A +G + + L+Q Sbjct: 107 LHEAAAKGKYEICKLLLQHGA 127 >5JHQ-A nrPDB Length = 482 Score = 128 bits (322), Expect = 7e-30, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 18/159 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + + L LL + H T LH+AA Y+ + +L++ ++ Sbjct: 172 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADV--- 228 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 ++ G LH A + + LL A V+A PL Sbjct: 229 --HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQF-------------TPLH 273 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP 247 AA N E+ LL+ HGAD + G + + + Sbjct: 274 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPE 312 Score = 126 bits (317), Expect = 3e-29, Method: Composition-based stats. Identities = 61/286 (21%), Positives = 104/286 (36%), Gaps = 49/286 (17%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL A ++ DV + +L+ + + LH AA + + L++ + Sbjct: 19 LLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV--- 75 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G LH A + +V LL + A +AR + PL Sbjct: 76 --HARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN-------------WNYTPLH 120 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY--NLLLSYDRHG 266 AA ++ +L++HGAD +++ G + L L K Y + LL R G Sbjct: 121 EAAIKGKIDVCIVLLQHGADPNIRNTDGKSALD-LADPSAKAVLTGEYKKDELLEAARSG 179 Query: 267 DH------LQPLDLVP---NHQGLTPFKLAGVEGNTVMFQHLMQKRK--HTQWTYG--PL 313 + L PL++ + + TP LA + Q L+Q H + G PL Sbjct: 180 NEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPL 239 Query: 314 TSTL----YDLTEIDSSGDEQSLLELIITTKKREARQILDQTPVKE 355 + Y++TE+ L+ A + TP+ E Sbjct: 240 HNACSYGHYEVTEL-----------LLKHGACVNAMDLWQFTPLHE 274 Score = 119 bits (298), Expect = 4e-27, Method: Composition-based stats. Identities = 53/259 (20%), Positives = 81/259 (31%), Gaps = 58/259 (22%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SPL AA + LL+ VH R G LH A + + E +L+ + Sbjct: 51 SPLHFAAGFGRKDVVEHLLQ-MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD-- 107 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTA--------------- 191 P + + T LH A + +++ LL A + R T Sbjct: 108 --PNARDNWN-YTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLT 164 Query: 192 --------------------------FRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEH 225 + PL AA N IV+LL++H Sbjct: 165 GEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 224 Query: 226 GADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFK 285 GAD+ A+D G LH + Y + +HG + +DL TP Sbjct: 225 GADVHAKDKGGLVPLHNACSYGH-------YEVTELLLKHGACVNAMDL----WQFTPLH 273 Query: 286 LAGVEGNTVMFQHLMQKRK 304 A + + L+ Sbjct: 274 EAASKNRVEVCSLLLSHGA 292 Score = 105 bits (262), Expect = 7e-23, Method: Composition-based stats. Identities = 47/259 (18%), Positives = 84/259 (32%), Gaps = 61/259 (23%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA N V+ + LL++ VH + G LH A Y + E +L++ + Sbjct: 204 TPLHLAAGYNRVRIVQLLLQH-GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV- 261 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS---VSARATGTAFR------RSPC 197 + T LH A + + LL+ A V+ R Sbjct: 262 ----NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 317 Query: 198 NLIYFG--------------------------------EHPLSFAACV---NSEEIVRLL 222 + G E L A +++ LL Sbjct: 318 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELL 377 Query: 223 IEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLT 282 + GA++ ++ T LH+ + + ++ +HG + LD + G T Sbjct: 378 LRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLH-------KHGAKMNALDTL----GQT 426 Query: 283 PFKLAGVEGNTVMFQHLMQ 301 A + G+ + L+ Sbjct: 427 ALHRAALAGHLQTCRLLLS 445 Score = 90.5 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 54/272 (19%), Positives = 86/272 (31%), Gaps = 82/272 (30%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 PL A + LLK+ V+ T LH AA + +E +L+ + Sbjct: 238 PLHNACSYGHYEVTELLLKH-GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 296 Query: 148 EPMTSE-----------------LYEGQ-------------------------------- 158 + ++G Sbjct: 297 VNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHE 356 Query: 159 TALHIAVVNQN---MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 215 TALH AV + + + LL + A+V+ + PL AA Sbjct: 357 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDF-------------MTPLHVAAERAH 403 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 275 +++ +L +HGA + A D+LG T LH L + Q LLLSY + Sbjct: 404 NDVMEVLHKHGAKMNALDTLGQTALHRAALAGH----LQTCRLLLSYGSD-------PSI 452 Query: 276 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQ 307 + QG T A GN Q ++ + + Sbjct: 453 ISLQGFT----AAQMGN-EAVQQILSESTPIR 479 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 10/104 (9%) Query: 73 RDEQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNL 132 R N+ ++ + + +PL +AA+ + ++L K++ +G+TALH AAL +L Sbjct: 379 RKGANVNEKNKDFMTPLHVAAERAHNDVM-EVLHKHGAKMNALDTLGQTALHRAALAGHL 437 Query: 133 EAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + +L+ + + +G T A N + + L Sbjct: 438 QTCRLLLSYGSDPSIISL-----QGFT----AAQMGNEAVQQIL 472 >5HKP-A nrPDB Length = 351 Score = 128 bits (322), Expect = 8e-30, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 18/159 (11%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ + + L LL + H T LH+AA Y+ + +L++ ++ Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADV--- 84 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 ++ G LH A + + LL A V+A PL Sbjct: 85 --HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQF-------------TPLH 129 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP 247 AA N E+ LL+ HGAD + G + + + Sbjct: 130 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPE 168 Score = 105 bits (262), Expect = 8e-23, Method: Composition-based stats. Identities = 47/259 (18%), Positives = 84/259 (32%), Gaps = 61/259 (23%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA N V+ + LL++ VH + G LH A Y + E +L++ + Sbjct: 60 TPLHLAAGYNRVRIVQLLLQH-GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV- 117 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS---VSARATGTAFR------RSPC 197 + T LH A + + LL+ A V+ R Sbjct: 118 ----NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 173 Query: 198 NLIYFG--------------------------------EHPLSFAACV---NSEEIVRLL 222 + G E L A +++ LL Sbjct: 174 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELL 233 Query: 223 IEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLT 282 + GA++ ++ T LH+ + + ++ +HG + LD + G T Sbjct: 234 LRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLH-------KHGAKMNALDSL----GQT 282 Query: 283 PFKLAGVEGNTVMFQHLMQ 301 A + G+ + L+ Sbjct: 283 ALHRAALAGHLQTCRLLLS 301 Score = 91.7 bits (226), Expect = 1e-18, Method: Composition-based stats. Identities = 60/293 (20%), Positives = 93/293 (31%), Gaps = 87/293 (29%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 PL A + LLK+ V+ T LH AA + +E +L+ + Sbjct: 94 PLHNACSYGHYEVTELLLKH-GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 152 Query: 148 EPMTSE-----------------LYEGQ-------------------------------- 158 + ++G Sbjct: 153 VNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHE 212 Query: 159 TALHIAVVNQN---MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 215 TALH AV + + + LL + A+V+ + PL AA Sbjct: 213 TALHCAVASLHPKRKQVAELLLRKGANVNEKNKDF-------------MTPLHVAAERAH 259 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 275 +++ +L +HGA + A DSLG T LH L + Q LLLSY + Sbjct: 260 NDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSYGSD-------PSI 308 Query: 276 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGD 328 + QG T A GN Q ++ + + + Y L E +GD Sbjct: 309 ISLQGFT----AAQMGN-EAVQQILSESTPMR-----TSDVDYRLLEASKAGD 351 Score = 72.4 bits (176), Expect = 7e-13, Method: Composition-based stats. Identities = 34/141 (24%), Positives = 52/141 (36%), Gaps = 23/141 (16%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A + N + ALL +V+ A+ PL AA N IV+LL+ Sbjct: 31 AARSGNEEKLMALLTP-LNVNCHASDGRKS-----------TPLHLAAGYNRVRIVQLLL 78 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD+ A+D G LH + Y + +HG + +DL TP Sbjct: 79 QHGADVHAKDKGGLVPLHNACSYGH-------YEVTELLLKHGACVNAMDL----WQFTP 127 Query: 284 FKLAGVEGNTVMFQHLMQKRK 304 A + + L+ Sbjct: 128 LHEAASKNRVEVCSLLLSHGA 148 Score = 56.6 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 48/104 (46%), Gaps = 10/104 (9%) Query: 73 RDEQNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNL 132 R N+ ++ + + +PL +AA+ + ++L K++ ++G+TALH AAL +L Sbjct: 235 RKGANVNEKNKDFMTPLHVAAERAHNDVM-EVLHKHGAKMNALDSLGQTALHRAALAGHL 293 Query: 133 EAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + +L+ + + +G T A N + + L Sbjct: 294 QTCRLLLSYGSDPSIISL-----QGFT----AAQMGNEAVQQIL 328 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 48/135 (35%), Gaps = 15/135 (11%) Query: 184 SARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 SA ++ Y + L A N E+++ LL + A D +T LH+ Sbjct: 6 SALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLA 65 Query: 244 ILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 ++ LLL +HG + D GL P A G+ + + L++ Sbjct: 66 A--GYNR--VRIVQLLL---QHGADVHAKDK----GGLVPLHNACSYGHYEVTELLLKHG 114 Query: 304 KHTQ----WTYGPLT 314 W + PL Sbjct: 115 ACVNAMDLWQFTPLH 129 >5CBO-A nrPDB Length = 176 Score = 126 bits (316), Expect = 4e-29, Method: Composition-based stats. Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 18/133 (13%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA + +LM ++ + G T LH+A + +V LL A Sbjct: 7 LLEAAHAGQDDEVRILMANGADV-----NAMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V+A G+ PL AA IV +L+++GAD+ AQD G T I Sbjct: 62 VNASDAT-------------GDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDI 108 Query: 243 LILQPNKTFACQM 255 I N+ A + Sbjct: 109 SIDNGNEDLAEIL 121 Score = 113 bits (283), Expect = 3e-25, Method: Composition-based stats. Identities = 31/139 (22%), Positives = 56/139 (40%), Gaps = 19/139 (13%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA + ++L V+ G T LH+AA + + E VL++ ++ Sbjct: 7 LLEAAHAGQDDEV-RILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADV--- 62 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G T LH+A + +V LL A V+A+ FG+ Sbjct: 63 --NASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDK-------------FGKTAFD 107 Query: 209 FAACVNSEEIVRLLIEHGA 227 + +E++ +L ++ A Sbjct: 108 ISIDNGNEDLAEILCKNKA 126 Score = 83.2 bits (204), Expect = 4e-16, Method: Composition-based stats. Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 6/95 (6%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA + + LLKY V+ A G+T LH+AA + L VL++ ++ Sbjct: 38 TPLHLAAYWGHFEIVEVLLKY-GADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADV- 95 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA 181 ++ G+TA I++ N N +L L +A Sbjct: 96 ----NAQDKFGKTAFDISIDNGNEDLAEILCKNKA 126 Score = 78.2 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 19/140 (13%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L AA ++ VR+L+ +GAD+ A D+ G T LH+ + ++ +LL Y G Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGH----FEIVEVLLKY---G 59 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK--HTQWTYGPLTSTLYDLTEID 324 + D G TP LA G + + L++ + Q +G T +D++ ID Sbjct: 60 ADVNASDAT----GDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGK---TAFDIS-ID 111 Query: 325 SSGDEQSLLELIITTKKREA 344 + ++ L E++ K ++A Sbjct: 112 NGNED--LAEILCKNKAQQA 129 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 ++PL LAAK + + LLKY V+ + G+TA I+ N + A +L + + Sbjct: 70 DTPLHLAAKWGYLGIVEVLLKY-GADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKAQ 127 >5ET1-A nrPDB Length = 353 Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats. Identities = 48/248 (19%), Positives = 86/248 (34%), Gaps = 34/248 (13%) Query: 79 LQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVL 138 + + R +P AA + L LL C+V ++ G T LH+AA + + + L Sbjct: 65 VSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWL 124 Query: 139 M-EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALL-ARRASVSARATGTAFRRSP 196 + + T G +H A ++ ++ L+ V+A+ Sbjct: 125 LYQGGANSAITTDT-----GALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNN------- 172 Query: 197 CNLIYFGEHPLSFAACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHILILQPNKTFACQM 255 G PL A E+ + L++ AD + G T LH + Sbjct: 173 ------GATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNP----- 221 Query: 256 YNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHT-QWTYGPLT 314 +L + + + +H G T A G+T + L+ Q +G Sbjct: 222 ---VLVWLVSFADVSFSEQ--DHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWG--G 274 Query: 315 STLYDLTE 322 + L+D E Sbjct: 275 TPLHDAAE 282 Score = 102 bits (254), Expect = 7e-22, Method: Composition-based stats. Identities = 35/163 (21%), Positives = 62/163 (38%), Gaps = 18/163 (11%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LA ++ ++ L++ H R G T LH AA + + L+ Sbjct: 175 TPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVS----FA 230 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + + ++G TA+H A + ++ LL A +S +G P Sbjct: 231 DVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS--------------QDLWGGTP 276 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNK 249 L AA E ++L +GA + +D G T + + Sbjct: 277 LHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHT 319 Score = 97.1 bits (240), Expect = 3e-20, Method: Composition-based stats. Identities = 45/216 (20%), Positives = 76/216 (35%), Gaps = 33/216 (15%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 + L LAA+ + LL G +H AA +L + +L+ PE V Sbjct: 107 TVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGV 166 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALL-ARRASVSARATGTAFRRSPCNLIYFGEH 205 + G T L++A ++ + + L+ A RA G Sbjct: 167 NAQTNN----GATPLYLACQEGHLEVTKYLVQECSADPHLRAQD-------------GMT 209 Query: 206 PLSFAACVNSEEIVRLLIEHGADI--RAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 PL AA + ++ L+ AD+ QD G T +H + + ++ + LL + Sbjct: 210 PLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGH----TKVLSWLLLHG 264 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHL 299 ++ + G TP A G Q L Sbjct: 265 A--------EISQDLWGGTPLHDAAENGELECCQIL 292 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 45/136 (33%), Gaps = 19/136 (13%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL AA+ L L+ + D ++ G TA+H AA + + L+ E+ Sbjct: 209 TPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEI- 267 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 S+ G T LH A N + + L A + R + G Sbjct: 268 -----SQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRD-------------HDGYTA 309 Query: 207 LSFAACVNSEEIVRLL 222 A R L Sbjct: 310 ADLAEFNGHTHCSRYL 325 Score = 37.0 bits (84), Expect = 0.033, Method: Composition-based stats. Identities = 33/198 (16%), Positives = 57/198 (28%), Gaps = 71/198 (35%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A +++++R+L A P P+ AA +R L+ Sbjct: 10 AARRGDLDVLRSLHAAG------------LLGPSLRDSLDALPVHHAARSGKLHCLRYLV 57 Query: 224 E-----------------------------------HGADIRAQDSLGNTVLHILILQPN 248 E G ++ +D+ G TVLH+ + Sbjct: 58 EEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGH 117 Query: 249 KTFACQMY--------------NLLLSYDRHGDHLQPLDLVPNH----------QGLTPF 284 + L + Y L L L+ H G TP Sbjct: 118 PDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPL 177 Query: 285 KLAGVEGNTVMFQHLMQK 302 LA EG+ + ++L+Q+ Sbjct: 178 YLACQEGHLEVTKYLVQE 195 >4OAU-C nrPDB Length = 699 Score = 103 bits (256), Expect = 4e-22, Method: Composition-based stats. Identities = 54/245 (22%), Positives = 94/245 (38%), Gaps = 41/245 (16%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVH-QRGAMGETALHIAALYDNLEAAMVLMEAAPELV- 146 L+ A ++ DV + +LL+ V+ Q G T LH A + +L+ + V Sbjct: 9 LIKAVQNEDVDLVQQLLEG-GANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVL 67 Query: 147 ---------------------------FEPMTSELYEGQTALHIAVVNQNMNLVRALLAR 179 + + G TA A V + ++ L R Sbjct: 68 RKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKR 127 Query: 180 RASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI-EHGADIRAQDSLGNT 238 A+V+ R + L G L AA E++++L+ E GAD+ A D++G Sbjct: 128 GANVNLR---RKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRN 184 Query: 239 VLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQH 298 L +L + + + +LLL HG + V +G TP LA + + + Q Sbjct: 185 ALIHALLSSDDSDVEAITHLLL---DHGADVN----VRGERGKTPLILAVEKKHLGLVQR 237 Query: 299 LMQKR 303 L+++ Sbjct: 238 LLEQE 242 Score = 78.6 bits (192), Expect = 1e-14, Method: Composition-based stats. Identities = 52/257 (20%), Positives = 96/257 (37%), Gaps = 42/257 (16%) Query: 81 QKRIWE---SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM- 136 Q+R+ + + L+ AA+ V+ L LL V+ MG AL A L + Sbjct: 141 QERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEA 200 Query: 137 ---VLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR 193 +L++ ++ G+T L +AV +++ LV+ LL + + T + Sbjct: 201 ITHLLLDHGADVNVRG-----ERGKTPLILAVEKKHLGLVQRLLE-QEHIEINDTDS--- 251 Query: 194 RSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFAC 253 G+ L A + ++I LL + GA D L++ + + Sbjct: 252 --------DGKTALLLAVELKLKKIAELLCKRGASTDCGD---------LVMTARRNYDH 294 Query: 254 QMYNLLLSYDRHGDHLQPLDL---VPNHQGLTPFKL----AGVEGNTVMFQHLMQKRKHT 306 + +LLS+ D P + +H G L + G F + +K K Sbjct: 295 SLVKVLLSHGAKEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFF--IDEKYKIA 352 Query: 307 QWTYGPLTSTLYDLTEI 323 + G + Y+ E+ Sbjct: 353 DTSEGGIYLGFYEKQEV 369 Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 58/143 (40%), Gaps = 23/143 (16%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 AV N++++LV+ LL A+V+ F+ G PL A ++ E+IV LL+ Sbjct: 12 AVQNEDVDLVQQLLEGGANVN-------FQEEEG-----GWTPLHNAVQMSREDIVELLL 59 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 HGAD + G T + + + LL + G + + G T Sbjct: 60 RHGADPVLRKKNGATPFILAAIAGS-------VKLLKLFLSKGADVNE----CDFYGFTA 108 Query: 284 FKLAGVEGNTVMFQHLMQKRKHT 306 F A V G + L ++ + Sbjct: 109 FMEAAVYGKVKALKFLYKRGANV 131 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 12/107 (11%) Query: 204 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGN-TVLHILILQPNKTFACQMYNLLLSY 262 H L A ++V+ L+E GA++ Q+ G T LH + + LLL Sbjct: 6 NHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV----ELLL-- 59 Query: 263 DRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWT 309 RHG ++ G TPF LA + G+ + + + K Sbjct: 60 -RHGADP----VLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNEC 101 >4O1O-A nrPDB Length = 717 Score = 98.2 bits (243), Expect = 1e-20, Method: Composition-based stats. Identities = 52/227 (22%), Positives = 85/227 (37%), Gaps = 17/227 (7%) Query: 79 LQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVL 138 Q++ SPL A + D + L LL R G T IA + N+ +L Sbjct: 36 FQEEEWGWSPLHSAVQM-DSEDLVALLLKHGADPCLRKRNGATPFIIAGITGNVRLLQLL 94 Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCN 198 + ++ G TA A V + +R L A V+ ++ Sbjct: 95 LPNVEDV-----NECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMH---RKTKQDQER 146 Query: 199 LIYFGEHPLSFAACVNSEEIVRLLIEH-GADIRAQDSLGNTVLHILILQPNKTFACQMYN 257 + G L AA +V +L+ A++ A+D++G L +L P+ A + Sbjct: 147 IRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITR 206 Query: 258 LLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 LLL HG + V TP LA N + Q L+++ + Sbjct: 207 LLL---DHGADVN----VRGEGSKTPLILAVERKNLDLVQMLLEQEQ 246 Score = 97.1 bits (240), Expect = 3e-20, Method: Composition-based stats. Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 26/232 (11%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME 140 +KR +P ++A +V+ L LL V++ G TA AA+Y +EA L E Sbjct: 71 RKRNGATPFIIAGITGNVRLLQ-LLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYE 129 Query: 141 AAPELVFEPMTSELYE-----GQTALHIAVVNQNMNLVRALL-ARRASVSARATGTAFRR 194 ++ T + E G TAL A ++ +V LL A +A V AR Sbjct: 130 NGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARD-----NM 184 Query: 195 SPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 254 L+Y +P ++ I RLL++HGAD+ + T L + + + N Sbjct: 185 GRNALVYALLNP----DDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLV-- 238 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHT 306 +LL ++ + + +G T LA + + L + T Sbjct: 239 --QMLLEQEQIEVNDT------DREGKTALLLAVELRLEEIAKLLCHRGAST 282 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 4/98 (4%) Query: 90 LLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL D +A+ +LL V+ RG +T L +A NL+ +L+E Sbjct: 193 LLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQ----EQIE 248 Query: 150 MTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA 187 + EG+TAL +AV + + + L R AS + Sbjct: 249 VNDTDREGKTALLLAVELRLEEIAKLLCHRGASTNCGD 286 Score = 63.2 bits (152), Expect = 5e-10, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 53/141 (37%), Gaps = 23/141 (16%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 AV ++ VR LL R A + + G PL A ++SE++V LL+ Sbjct: 15 AVQEADIEQVRQLLERGADANFQEEEW------------GWSPLHSAVQMDSEDLVALLL 62 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 +HGAD + G T I + N ++ LLL + + G T Sbjct: 63 KHGADPCLRKRNGATPFIIAGITGN----VRLLQLLLPNVEDVNE-------CDVNGFTA 111 Query: 284 FKLAGVEGNTVMFQHLMQKRK 304 F A V G + L + Sbjct: 112 FMEAAVYGRVEALRFLYENGA 132 >1WG0-A nrPDB Length = 243 Score = 97.8 bits (242), Expect = 2e-20, Method: Composition-based stats. Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 23/205 (11%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 PL A +N+ + +LL + + Q+ G LH + + E L+ + Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 148 EPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPL 207 + + G T HIA N+ +V++L + + G L Sbjct: 65 DDYPDD--SGWTPFHIACSVGNLEVVKSLY-----------DRPLKPDLNKITNQGVTCL 111 Query: 208 SFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGD 267 A E+ + LIE+GA +R +D LH + ++ LL + Sbjct: 112 HLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGS----LKLIELLCGLGKSAV 167 Query: 268 HLQPLDLVPNHQGLTPFKLAGVEGN 292 + Q + QG TP A EG+ Sbjct: 168 NWQ------DKQGWTPLFHALAEGH 186 Score = 82.4 bits (202), Expect = 7e-16, Method: Composition-based stats. Identities = 44/183 (24%), Positives = 70/183 (38%), Gaps = 19/183 (10%) Query: 78 LLQQKRIWESPLLLAAKDNDVQALNKLL-KYEDCKVHQ-RGAMGETALHIAALYDNLEAA 135 LLQ+ + PL + + + LL K E+ + G T HIA NLE Sbjct: 29 LLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVV 88 Query: 136 MVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRS 195 L + + + +G T LH+AV + + + L+ ASV + Sbjct: 89 KSLYD---RPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDK------- 138 Query: 196 PCNLIYFGEHPLSFAACVNSEEIVRLLIEHGAD-IRAQDSLGNTVLHILILQPNKTFACQ 254 F + PL AA V S +++ LL G + QD G T L + + + A Sbjct: 139 ------FNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVL 192 Query: 255 MYN 257 + Sbjct: 193 LVE 195 Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 17/134 (12%), Positives = 38/134 (28%), Gaps = 31/134 (23%) Query: 87 SPLLLAAKDNDVQALNKLL-KYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 +P +A +++ + L + +++ G T LH+A E + L+E + Sbjct: 74 TPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASV 133 Query: 146 V-----------------------------FEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + + +G T L A+ + + L Sbjct: 134 RIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLL 193 Query: 177 L-ARRASVSARATG 189 + A Sbjct: 194 VEKYGAEYDLVDNK 207 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 9/100 (9%) Query: 204 EHPLSFAACVNSE-EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 262 +PL A N ++ LL + + +D G LH + A ++ + LLS Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQ----AHEITSFLLSK 58 Query: 263 DRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 + + LD P+ G TPF +A GN + + L + Sbjct: 59 MENVN----LDDYPDDSGWTPFHIACSVGNLEVVKSLYDR 94 >3EU9-A nrPDB Length = 240 Score = 96.3 bits (238), Expect = 5e-20, Method: Composition-based stats. Identities = 33/172 (19%), Positives = 63/172 (36%), Gaps = 19/172 (11%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL A + + + +L+KY G + +H+AA + + L+ ++ Sbjct: 78 TPLHWATRQGHLSMVVQLMKY-GADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 136 Query: 147 FEPMTSELYEGQTALHIAVVNQN-MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 G T L A + ++ R LL SV+ Y Sbjct: 137 MMDQN-----GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDK------------YHKNT 179 Query: 206 PLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYN 257 L +A + ++ LL+E GA++ AQ+ G + L + + N + Sbjct: 180 ALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQE 231 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 54/228 (23%), Positives = 84/228 (36%), Gaps = 33/228 (14%) Query: 80 QQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGA-MGETALHIAALYDNLEAAMVL 138 Q + + L AA +N + L K + V Q G + T LH A +L + L Sbjct: 37 QPDKENVTLLHWAAINNRID-LVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQL 95 Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCN 198 M+ + EG + +H+A + ++V L+A+ V Sbjct: 96 MKYGADPSL-----IDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN--------- 141 Query: 199 LIYFGEHPLSFAACVNS-EEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNKTFACQMY 256 G PL +AA + RLL+ + D NT LH +L N T + Sbjct: 142 ----GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTT----VI 193 Query: 257 NLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 +LLL + D N +G + LA N M HL + R+ Sbjct: 194 SLLLEAGANVD-------AQNIKGESALDLAKQRKNVWMINHLQEARQ 234 Score = 89.0 bits (219), Expect = 7e-18, Method: Composition-based stats. Identities = 40/216 (18%), Positives = 72/216 (33%), Gaps = 27/216 (12%) Query: 92 AAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 A + + +L++ V Q T LH AA+ + ++ + + Sbjct: 16 ATQYGIYERCRELVEA-GYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGD 74 Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 T LH A ++++V L+ A S G + AA Sbjct: 75 LN----STPLHWATRQGHLSMVVQLMKYGADPSLIDGE-------------GCSCIHLAA 117 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQP 271 IV LI G D+ D G T L + + + LLL+++ Sbjct: 118 QFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTR---LLLTFNV------S 168 Query: 272 LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQ 307 ++L + T A + GNT + L++ + Sbjct: 169 VNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVD 204 Score = 68.6 bits (166), Expect = 1e-11, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 57/164 (34%), Gaps = 28/164 (17%) Query: 125 IAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVS 184 A Y E L+EA ++ E T LH A +N ++LV+ +++ A V Sbjct: 15 KATQYGIYERCRELVEAGYDV-----RQPDKENVTLLHWAAINNRIDLVKYYISKGAIVD 69 Query: 185 ARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILI 244 PL +A +V L+++GAD D G + +H+ Sbjct: 70 ------------QLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAA 117 Query: 245 LQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAG 288 + + + G + + + G+TP A Sbjct: 118 QFGHTSIVAYL-------IAKGQDV----DMMDQNGMTPLMWAA 150 >6CUD-A nrPDB Length = 806 Score = 94.8 bits (234), Expect = 1e-19, Method: Composition-based stats. Identities = 97/679 (14%), Positives = 201/679 (29%), Gaps = 154/679 (22%) Query: 86 ESPLLLAAKDNDVQALNKLLK-YEDCKVHQRGAMGETALHIAALYDNLEAAMVLME---- 140 E L AA+ ++ + K+L+ + V+ MG+ AL +A ++LE +L++ Sbjct: 28 EERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENL 87 Query: 141 -----------------------------AAPELVFEPMTSE---------LYEGQ---- 158 A+ L P E +G Sbjct: 88 ARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSP 147 Query: 159 --TALHIAVVNQNMNLVRALLARRASVSAR-----ATGTAFRRSPCNLI---------YF 202 T + +A Q +V LL + A + G + + Y Sbjct: 148 DITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYK 207 Query: 203 G-EHPLSFAACVNSEEIVRLLIEHG-ADIRAQDSLGNTVLHILILQPNKTFACQMYNL-- 258 G P + + L + + A + + L +Q K F + +L Sbjct: 208 GLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQC-KDFVVGVLDLCR 266 Query: 259 -------LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHL-MQKRKHTQWTY 310 +L+ D PL++ + L+ KLA H Q++ T W Sbjct: 267 DSEEVEAILNGDLESAE--PLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIW-- 322 Query: 311 GPLTSTLYDLTEIDSSGDEQSLLELIITTKKREARQILDQ----TPVKELVSLKWKRYGR 366 + ++ ++ ++ L P L + + + Sbjct: 323 ---------YENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMK 373 Query: 367 PYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRL 426 I L ++ F + + N + + + K Q + Sbjct: 374 FVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWT-------- 425 Query: 427 VGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVL-IITYAFMVLVTMVMRLI 485 E++ ++ + ++ E +++ G + Q F +L I AF ++ Sbjct: 426 --EMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQAT 483 Query: 486 SASGEVVPMS--------------------------------------FALVLGWCNVMY 507 A V A+VL + + Y Sbjct: 484 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 543 Query: 508 FARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYP 567 + GP I + + + D+ +F L +V F +I++ Sbjct: 544 ILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSYYLGA---KVNAAF 599 Query: 568 MALFSTFELFLTIIDGPAN-----YNVDLPFM---YSITYAAFAIIATLLMLNLLIAMMG 619 + +F+ I G + D F+ + Y + + +++LN+LIAM+ Sbjct: 600 TTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMIN 659 Query: 620 DTHWRVAHERDELWRAQIV 638 ++ + + D W+ Sbjct: 660 SSYQEIEDDSDVEWKFARS 678 >4OT9-A nrPDB Length = 359 Score = 92.5 bits (228), Expect = 7e-19, Method: Composition-based stats. Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 24/165 (14%) Query: 83 RIWESPLLLA--AKDNDVQALNKLLKYEDCKV----HQRGAMGETALHIAALYDNLEAAM 136 R +S + LA A + L LL+ V H G +H+A + E Sbjct: 152 RHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLD 211 Query: 137 VLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLAR-RASVSARATGTAFRRS 195 +L+++ E+ +E G+TALH+A + + LV L+ + RA+V+AR Sbjct: 212 LLVDSGAEVE----ATERQGGRTALHLATEMEELGLVTHLVTKLRANVNART-------- 259 Query: 196 PCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL 240 + G PL AA + + RLL++ GADI A++ L Sbjct: 260 -----FAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 45/235 (19%), Positives = 80/235 (34%), Gaps = 31/235 (13%) Query: 78 LLQQKRIWESPLLLAAKDNDVQALNKLL-KYEDCK----VHQRGAMGETALHIAALYDNL 132 L Q ++PL LA + +++ + V+ + +T LH+A + Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134 Query: 133 EAAMVLMEAAPELVFEPMTSELYEGQTALHIA--VVNQNMNLVRALLARRASVSARATGT 190 L+ + G +A+H+A L+RALL A Sbjct: 135 SVVSFLLRVGADPALL-----DRHGDSAMHLALRAGAGAPELLRALLQSGA--------P 181 Query: 191 AFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNK 249 A + + G +P+ A S E + LL++ GA++ A + G T LH+ Sbjct: 182 AVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEEL 241 Query: 250 TFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 + L+ G TP LA G + + L++ Sbjct: 242 GLVTHLV----------TKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGA 286 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 41/208 (19%), Positives = 78/208 (37%), Gaps = 18/208 (8%) Query: 150 MTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSF 209 +T++ G T LH+A+++ +++ ++ A+ G + + + PL Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVY--VIHHAQDLGVVNLTNHLH-----QTPLHL 127 Query: 210 AACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHL 269 A +V L+ GAD D G++ +H+ + LL + + G Sbjct: 128 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA-----PELLRALLQSGAPA 182 Query: 270 QP-LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGD 328 P L +P+ +GL P LA + L+ + T T L + + Sbjct: 183 VPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLA---TEME 239 Query: 329 EQSLLELIITT--KKREARQILDQTPVK 354 E L+ ++T AR TP+ Sbjct: 240 ELGLVTHLVTKLRANVNARTFAGNTPLH 267 Score = 52.4 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 44/142 (30%), Gaps = 19/142 (13%) Query: 173 VRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR---LLIEHGAD- 228 RALL + ARA R G+ PL A ++ +I H D Sbjct: 52 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 111 Query: 229 --IRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKL 286 + + L T LH+ ++ + R G LD G + L Sbjct: 112 GVVNLTNHLHQTPLHLAVITGQTSVVS-------FLLRVGADPALLD----RHGDSAMHL 160 Query: 287 A--GVEGNTVMFQHLMQKRKHT 306 A G + + L+Q Sbjct: 161 ALRAGAGAPELLRALLQSGAPA 182 >3ZKJ-A nrPDB Length = 261 Score = 86.7 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 40/189 (21%), Positives = 69/189 (36%), Gaps = 20/189 (10%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SP+ AA Q + L + V+ A + LH A L +L +L++ ++ Sbjct: 5 SPMHEAAIHGH-QLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQV- 62 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 +T++ T L A V+ + + V LL ASV + P Sbjct: 63 -NGVTADW---HTPLFNACVSGSWDCVNLLLQHGASVQPESDL--------------ASP 104 Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 + AA E V LI +G +I + S T L++ + ++ ++ Sbjct: 105 IHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQGK 164 Query: 267 DHLQPLDLV 275 PL V Sbjct: 165 GQDSPLHAV 173 Score = 80.5 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 68/183 (37%), Gaps = 42/183 (22%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL- 145 SPL A + + LLK+ +V+ A T L A + + + +L++ + Sbjct: 38 SPLHEACLGGHLSCVKILLKH-GAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ 96 Query: 146 ----VFEPMTSELYEGQ----------------------TALHIAVVNQNMNLVRALLAR 179 + P+ G T L++A NQ V+ LL Sbjct: 97 PESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLES 156 Query: 180 RASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTV 239 A V+ + G + PL A SEE+ LL++ GAD +A+++ G Sbjct: 157 GADVN-QGKGQ-------------DSPLHAVARTASEELACLLMDFGADTQAKNAEGKRP 202 Query: 240 LHI 242 + + Sbjct: 203 VEL 205 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 58/161 (36%), Gaps = 25/161 (15%) Query: 158 QTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEE 217 + +H A ++ + +R L+++ +V+ PL A Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHV-------------SPLHEACLGGHLS 50 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPN 277 V++L++HGA + + +T L + + NLLL +HG +QP + Sbjct: 51 CVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCV----NLLL---QHGASVQPESDLA- 102 Query: 278 HQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLY 318 +P A G+ L+ + L + LY Sbjct: 103 ----SPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLY 139 Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 7/108 (6%) Query: 79 LQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVL 138 +Q + SP+ AA+ V+ +N L+ Y H+ +G T L++A L Sbjct: 95 VQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLG-TPLYLACENQQRACVKKL 153 Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSAR 186 +E+ ++ + LH + L L+ A A+ Sbjct: 154 LESGADVNQGKGQD------SPLHAVARTASEELACLLMDFGADTQAK 195 Score = 37.8 bits (86), Expect = 0.021, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 49/150 (32%), Gaps = 15/150 (10%) Query: 204 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 P+ AA + +R LI G + + + LH L + +LL Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGH----LSCVKILL--- 56 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEI 323 +HG + + TP A V G+ L+Q Q P + + E Sbjct: 57 KHGAQVNGVTA----DWHTPLFNACVSGSWDCVNLLLQHGASVQ----PESDLASPIHEA 108 Query: 324 DSSGDEQSLLELIITTKKREARQILDQTPV 353 G + + LI + + TP+ Sbjct: 109 ARRGHVECVNSLIAYGGNIDHKISHLGTPL 138 >6CV9-A nrPDB Length = 842 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 60/152 (39%), Gaps = 12/152 (7%) Query: 495 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQT 554 + A+VL + + Y + GP I + + + D+ +F + +V + F + ++ Sbjct: 511 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 569 Query: 555 EDPEELGHFYDYPMALFSTFELFLTIIDGPAN-----YNVDLPFM---YSITYAAFAIIA 606 + + +F+ I G + N + F+ + Y + + Sbjct: 570 YIGA---KQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTM 626 Query: 607 TLLMLNLLIAMMGDTHWRVAHERDELWRAQIV 638 +++LN+LIAM+ + + + D W+ Sbjct: 627 VIVLLNMLIAMINSSFQEIEDDADVEWKFARA 658 Score = 58.9 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 56/161 (34%), Gaps = 23/161 (14%) Query: 84 IWESPLLLAAKDNDVQALNKLLKYEDC-KVHQRGAMGETALHIAALYDNLEAAMVLMEAA 142 I E L AA+ ++ + K+L+ V+ MG+ AL +A ++LE +L++ Sbjct: 8 IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK-- 65 Query: 143 PELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA------------SVSARATGT 190 L AL +A+ + +V A+L A + Sbjct: 66 --------KENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 117 Query: 191 AFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRA 231 P+ AA EIV L+ GA I Sbjct: 118 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIER 158 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 56/182 (30%), Gaps = 40/182 (21%) Query: 126 AALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA 185 AA Y N+ ++E E + Y GQ AL +AV N+++ + LL + + Sbjct: 16 AAEYGNIPVVRKMLE---ECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE---NL 69 Query: 186 RATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILIL 245 G A L A IV ++ H A + G + Sbjct: 70 SRVGDA---------------LLLAISKGYVRIVEAILNHPAF-----AEGKR---LATS 106 Query: 246 QPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKH 305 + +YD G +TP LA + L++K Sbjct: 107 PSQSELQ---QDDFYAYDEDGTRFS--------HDVTPIILAAHCQEYEIVHTLLRKGAR 155 Query: 306 TQ 307 + Sbjct: 156 IE 157 >1BD8-A nrPDB Length = 156 Score = 82.4 bits (202), Expect = 6e-16, Method: Composition-based stats. Identities = 31/164 (18%), Positives = 60/164 (36%), Gaps = 20/164 (12%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 L AA DVQ + +LL E G+TAL + ++ + A+ L++ Sbjct: 6 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGA----- 59 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G + +H A ++ ++ L+ A V+ G P+ Sbjct: 60 SPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT-------------GALPIH 106 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 252 A +V L +D+ +D+ G T L + + + + Sbjct: 107 LAVQEGHTAVVSFL-AAESDLHRRDARGLTPLELALQRGAQDLV 149 Score = 62.8 bits (151), Expect = 6e-10, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 67/171 (39%), Gaps = 30/171 (17%) Query: 126 AALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA 185 AA +++ L+ + P + G+TAL + ++ + + LL + AS + Sbjct: 9 AAARGDVQEVRRLLH---RELVHPDALNRF-GKTALQV-MMFGSTAIALELLKQGASPNV 63 Query: 186 RATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILIL 245 + T G P+ AA + +++L+EHGAD+ D G +H+ + Sbjct: 64 QDTS-------------GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQ 110 Query: 246 QPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMF 296 + + S+ L + +GLTP +LA G + Sbjct: 111 EGHTAVV--------SFLAAESDLHR----RDARGLTPLELALQRGAQDLV 149 Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 32/90 (35%), Gaps = 7/90 (7%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SP+ AA+ + L L+++ V+ G +H+A + L Sbjct: 70 SPVHDAARTGFLDTLKVLVEH-GADVNVPDGTGALPIHLAVQEGHTAVVSFL------AA 122 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + G T L +A+ +LV L Sbjct: 123 ESDLHRRDARGLTPLELALQRGAQDLVDIL 152 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 38/159 (23%), Positives = 53/159 (33%), Gaps = 27/159 (16%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A ++ VR LL R P L FG+ L S I L+ Sbjct: 9 AAARGDVQEVRRLLHRE------------LVHPDALNRFGKTALQV-MMFGSTAIALELL 55 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 + GA QD+ G + +H + L HG + VP+ G P Sbjct: 56 KQGASPNVQDTSGTSPVHDAARTG-------FLDTLKVLVEHGADVN----VPDGTGALP 104 Query: 284 FKLAGVEGNTVMFQHL-MQKRKHTQWTYG--PLTSTLYD 319 LA EG+T + L + H + G PL L Sbjct: 105 IHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQR 143 >1G3N-B nrPDB Length = 168 Score = 75.1 bits (183), Expect = 1e-13, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 62/173 (35%), Gaps = 21/173 (12%) Query: 85 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 W + L AA D++ L LL+ Q G G TAL + L N E A L+ Sbjct: 5 WGNELASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVMKL-GNPEIARRLLLRGAN 62 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 204 + T G +H A ++ ++ LL +A V+ G Sbjct: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE-------------GN 104 Query: 205 HPLSFAACVNSEEIVRLLIEHGAD-IRAQDSLGNTVLHILILQPNKTFACQMY 256 PL AA +V L++H A + ++ G+T + L M Sbjct: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 49/138 (35%), Gaps = 18/138 (13%) Query: 90 LLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 L K + + +LL + G +H AA L+ L+E ++ Sbjct: 42 LQVMKLGNPEIARRLLL-RGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV---- 96 Query: 150 MTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSF 209 E EG LH+A ++ +V L+ AS + + + G+ Sbjct: 97 -NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS------------NVGHRNHKGDTACDL 143 Query: 210 AACVNSEEIVRLLIEHGA 227 A E+V L+ +GA Sbjct: 144 ARLYGRNEVVSLMQANGA 161 Score = 62.4 bits (150), Expect = 7e-10, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 41/101 (40%), Gaps = 5/101 (4%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME 140 + R + + AA+ + L LL+++ V+ G LH+AA +L L++ Sbjct: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 Query: 141 AAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA 181 V ++G TA +A + +V + A A Sbjct: 125 HTASNVGH----RNHKGDTACDLARLYGRNEVVSLMQANGA 161 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 37/174 (21%), Positives = 63/174 (36%), Gaps = 29/174 (16%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA +LE L++ + + G+TAL + + N + R LL R A+ Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-----FGRTALQV-MKLGNPEIARRLLLRGAN 62 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 + G + AA + ++ L+E AD+ +D+ GN LH+ Sbjct: 63 PDLKDRT-------------GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHL 109 Query: 243 LILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMF 296 + + + S H NH+G T LA + G + Sbjct: 110 AAKEGHLRVVEFLVKHTASNVGH----------RNHKGDTACDLARLYGRNEVV 153 Score = 49.7 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 56/171 (32%), Gaps = 25/171 (14%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A ++ + +LL + FG L + + EI R L+ Sbjct: 12 AAARGDLEQLTSLLQN-------------NVNVNAQNGFGRTALQV-MKLGNPEIARRLL 57 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 GA+ +D G V+H + L + + + +++G P Sbjct: 58 LRGANPDLKDRTGFAVIHDAARAG-------FLDTLQTLLEFQADVN----IEDNEGNLP 106 Query: 284 FKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLE 334 LA EG+ + + L++ T DL + + SL++ Sbjct: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 >1BLX-B nrPDB Length = 166 Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 58/163 (35%), Gaps = 20/163 (12%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 L AA DVQ + +LL E G+TAL + A +L + A Sbjct: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASP---- 67 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLS 208 + G + +H A ++ ++ L+ A V+A + G P+ Sbjct: 68 --NVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDST-------------GSLPIH 112 Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTF 251 A +V L +D+ +D+ G T L + + + Sbjct: 113 LAIREGHSSVVSFLAPE-SDLHHRDASGLTPLELARQRGAQNL 154 Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 32/90 (35%), Gaps = 7/90 (7%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SP+ AA+ + L L+++ V+ + G +H+A + L Sbjct: 76 SPVHDAARTGFLDTLKVLVEH-GADVNALDSTGSLPIHLAIREGHSSVVSFL------AP 128 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + G T L +A NL+ L Sbjct: 129 ESDLHHRDASGLTPLELARQRGAQNLMDIL 158 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 45/136 (33%), Gaps = 24/136 (17%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A ++ VR LL R P L FG+ L S + L+ Sbjct: 15 AAARGDVQEVRRLLHRE------------LVHPDALNRFGKTALQV-MMFGSPAVALELL 61 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 + GA QD+ G + +H + L HG + LD G P Sbjct: 62 KQGASPNVQDASGTSPVHDAARTG-------FLDTLKVLVEHGADVNALDST----GSLP 110 Query: 284 FKLAGVEGNTVMFQHL 299 LA EG++ + L Sbjct: 111 IHLAIREGHSSVVSFL 126 >6EMK-G nrPDB Length = 426 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 68/161 (42%), Gaps = 16/161 (9%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGA-MGETALHIAALYDNLEAAMVLMEAAPELVF 147 L A + ++ + +LL+ + + G ++LH A+ + + L++ + Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHE 68 Query: 148 EPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPL 207 T ++G T +H+A++ + + LL + F R + G P+ Sbjct: 69 LIKT---FKGNTCVHLALMKGHEQTLHLLLQQ------------FPRFINHRGENGRAPI 113 Query: 208 SFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 248 A + + + LLI GAD+ D+ G+T LH+ + + Sbjct: 114 HIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGS 154 Score = 62.0 bits (149), Expect = 9e-10, Method: Composition-based stats. Identities = 27/161 (16%), Positives = 54/161 (33%), Gaps = 21/161 (13%) Query: 87 SPLLLAAKDNDVQALNKLLKYEDCK-VHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 S L A+ L++ K + G T +H+A + + + +L++ P Sbjct: 42 SSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRF 101 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 + G+ +HIA +N + L+ A + T G+ Sbjct: 102 INH----RGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTN-------------GDT 144 Query: 206 PLSFAACVNSEEIVRLLIEHGA---DIRAQDSLGNTVLHIL 243 PL S +++L+ G D +D + + Sbjct: 145 PLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVA 185 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 44/122 (36%), Gaps = 8/122 (6%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + + LA Q L+ LL+ ++ RG G +HIA + D + +L+ +L Sbjct: 76 NTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADL 135 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA---SVSARATGTAFRRSPCNLIYF 202 G T LH+ + +++ ++ LL + R G Sbjct: 136 WVMDTN-----GDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEV 190 Query: 203 GE 204 G Sbjct: 191 GN 192 Score = 42.8 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 54/172 (31%), Gaps = 44/172 (25%) Query: 161 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 220 L A++ N+ +V+ LL R + G L +A+ I Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSEN-----------GWSSLHYASYHGRYLICV 57 Query: 221 LLIEHGADIR--AQDSLGNTVLHILILQPNKT-------------------------FAC 253 LI+ G D + GNT +H+ +++ ++ AC Sbjct: 58 YLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIAC 117 Query: 254 --QMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 303 Y L G L +D G TP + G+ + L+ + Sbjct: 118 MNDYYQCLSLLIGVGADLWVMDT----NGDTPLHVCLEYGSISCMKMLLNEG 165 >3LJN-A nrPDB Length = 364 Score = 72.4 bits (176), Expect = 6e-13, Method: Composition-based stats. Identities = 39/211 (18%), Positives = 74/211 (35%), Gaps = 26/211 (12%) Query: 89 LLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 + +AA+ + +L++ + G TALH+A + ++ A L Sbjct: 24 IHVAARKGQTDEVRRLIE-TGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG------ 76 Query: 149 PMTSELYEGQTALHIAVVNQNMNLVRALLARRAS---------VSARATGTAFRRSPCNL 199 L+ GQ +H+AV+ +LV AL+ A ++ Sbjct: 77 -EVHSLWHGQKPIHLAVMANKTDLVVALVE-GAKERGQMPESLLNECDEREVNEIGSHVK 134 Query: 200 IYFGEHPLSFAACVN--SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYN 257 G+ L + + E++++L++ GA A+D T L + N+ M + Sbjct: 135 HCKGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMD 194 Query: 258 LLLSYDRHGDHLQPLDLVPNHQGLTPFKLAG 288 + S N QG + A Sbjct: 195 TVPSKSSLRLD------YANKQGNSHLHWAI 219 Score = 60.5 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 41/209 (19%), Positives = 75/209 (35%), Gaps = 50/209 (23%) Query: 81 QKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAM--GETALHIAALYDNLEAAMVL 138 Q R + L LA K V L V + ++ G+ +H+A + + + + L Sbjct: 49 QNRFGCTALHLACKFGCVDTAKYL-----ASVGEVHSLWHGQKPIHLAVMANKTDLVVAL 103 Query: 139 MEAAPELVFEPMT----------------SELYEGQTALHIAVVNQ--NMNLVRALLARR 180 +E A E P + + +GQTALH V + +++ L+ Sbjct: 104 VEGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPEYLEMIKILVQLG 163 Query: 181 ASVSARATGT----------------------AFRRSPCNLIYF---GEHPLSFAACVNS 215 AS +A+ +S L Y G L +A +N Sbjct: 164 ASPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQGNSHLHWAILINW 223 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLHILI 244 E++ +E G D+ +D+ L++ + Sbjct: 224 EDVAMRFVEMGIDVNMEDNEHTVPLYLSV 252 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 32/98 (32%), Gaps = 13/98 (13%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 + AA + VR LIE G Q+ G T LH+ A Y Sbjct: 24 IHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAK--------YLASV 75 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 + L G P LA + T + L++ K Sbjct: 76 GEVHSL-----WHGQKPIHLAVMANKTDLVVALVEGAK 108 >3EHQ-A nrPDB Length = 222 Score = 72.4 bits (176), Expect = 8e-13, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 5/107 (4%) Query: 80 QQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLM 139 +Q ++PL AAK ++ L + V+ G TAL+ A + + +L Sbjct: 68 EQAESIDNPLHEAAKRGNLSWLRE-CLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLF 126 Query: 140 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSAR 186 + + G TALH A ++V+ LLA+ A R Sbjct: 127 TQ----PNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLR 169 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 38/122 (31%), Gaps = 17/122 (13%) Query: 122 ALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA 181 LH AA NL ++ + G TAL+ A + ++V L + Sbjct: 76 PLHEAAKRGNLSWLRECLDN-----RVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQ-- 128 Query: 182 SVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLH 241 G+ L AA +IV+LL+ GA ++ Sbjct: 129 ----------PNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFD 178 Query: 242 IL 243 + Sbjct: 179 MA 180 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 37/104 (35%), Gaps = 10/104 (9%) Query: 204 EHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 ++PL AA + +R +++ + D G+T L+ +K + + Sbjct: 74 DNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVE------MLFT 127 Query: 264 RHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQ 307 + L N G T A +G + Q L+ K T Sbjct: 128 QPNIELNQQ----NKLGDTALHAAAWKGYADIVQLLLAKGARTD 167 >5DND-A nrPDB Length = 588 Score = 72.0 bits (175), Expect = 8e-13, Method: Composition-based stats. Identities = 52/204 (25%), Positives = 73/204 (35%), Gaps = 32/204 (15%) Query: 99 QALNKLLKYEDCKVHQRGAMGETA-LHIA-ALYDNLEAAMVLMEAAPELVFEPMTSELYE 156 Q + +L C+ L +A A LEA LME +L + Sbjct: 400 QGVARLFSLFGCQEEDSVQDAVMPSLALALAHAGELEALQALMELGSDLRLKDSN----- 454 Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 GQT LH+A N +V LL R V+AR G PL A Sbjct: 455 GQTLLHVAARNGRDGVVTMLLHRGMDVNARDRD-------------GLSPLLLAVQGRHR 501 Query: 217 EIVRLLIEHGADIRAQD-SLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLV 275 E +RLL + GA + QD T L L + + L ++ + G LQ Sbjct: 502 ECIRLLRKAGACLSPQDLKDAGTELCRLASRAD-------MEGLQAWGQAGADLQQ---- 550 Query: 276 PNHQGLTPFKLAGVEGNTVMFQHL 299 P + G + +A GN + L Sbjct: 551 PGYDGRSALCVAEAAGNQEVLALL 574 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 50/137 (36%), Gaps = 18/137 (13%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 ++ L +AA++ + LL + V+ R G + L +A + E +L +A L Sbjct: 456 QTLLHVAARNGRDGVVTMLL-HRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGACL 514 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEH 205 +L + T L +M ++A A + Y G Sbjct: 515 SP----QDLKDAGTELCRLASRADMEGLQAWGQAGADLQ-------------QPGYDGRS 557 Query: 206 PLSFAACVNSEEIVRLL 222 L A ++E++ LL Sbjct: 558 ALCVAEAAGNQEVLALL 574 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 39/99 (39%), Gaps = 12/99 (12%) Query: 207 LSFA-ACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRH 265 L+ A A E ++ L+E G+D+R +DS G T+LH+ + + Sbjct: 425 LALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLH-------R 477 Query: 266 GDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 304 G + + GL+P LA + + L + Sbjct: 478 GMDVNA----RDRDGLSPLLLAVQGRHRECIRLLRKAGA 512 >5D68-A nrPDB Length = 486 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 60/166 (36%), Gaps = 26/166 (15%) Query: 65 RRESWAQSRDEQNLLQQKRIW--ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETA 122 ++E W +S ++R W + PL +A + D + L++LL E V+Q + Sbjct: 17 KQEKWQRSMSSVTE-DKERQWVDDFPLHRSACEGDSELLSRLL-SERFSVNQLDSDHWAP 74 Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQ--TALHIAVVNQNMNLVRALLARR 180 +H A Y +EA +L+E L GQ + LH A + +V+ LL Sbjct: 75 IHYACWYGKVEATRILLEKGK------CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH- 127 Query: 181 ASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS--EEIVRLLIE 224 G PL+ E L++ Sbjct: 128 -----------PETDRHITDQQGRSPLNICEENKQNNWEEAAKLLK 162 Score = 59.7 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 43/129 (33%), Gaps = 18/129 (13%) Query: 122 ALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA 181 LH +A + E L+ + S+ + +H A + R LL + Sbjct: 41 PLHRSACEGDSELLSRLLS--ERFSVNQLDSDHWA---PIHYACWYGKVEATRILLEKGK 95 Query: 182 SVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHG-ADIRAQDSLGNTVL 240 +P L PL FAA EIV++L+ H D D G + L Sbjct: 96 C------------NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 143 Query: 241 HILILQPNK 249 +I Sbjct: 144 NICEENKQN 152 >3UI2-A nrPDB Length = 244 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 18/124 (14%) Query: 120 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLAR 179 ET AA + +A L+E + + G+TAL + VR L Sbjct: 46 ETPWWTAARKADEQALSQLLE------DRDVDAVDENGRTALLFVAGLGSDKCVRLLAEA 99 Query: 180 RASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTV 239 A + R + G L AA E+V L+E GADI +D G T Sbjct: 100 GADLDHRD------------MRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTA 147 Query: 240 LHIL 243 L + Sbjct: 148 LELA 151 Score = 63.2 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 6/103 (5%) Query: 85 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +E+P AA+ D QAL++LL ED V G TAL A + + +L EA + Sbjct: 45 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA 187 L M G TALH+A +V AL+ A + Sbjct: 103 LDHRDMR----GGLTALHMAAGYVRPEVVEALVELGADIEVED 141 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 30/110 (27%), Positives = 40/110 (36%), Gaps = 18/110 (16%) Query: 69 WAQSR--DEQNLLQQKRIWE---------SPLLLAAKDNDVQALNKLLKYEDCKVHQRGA 117 W +R DEQ L Q + + LL A +LL + R Sbjct: 50 WTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLG-SDKCVRLLAEAGADLDHRDM 108 Query: 118 MG-ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVV 166 G TALH+AA Y E L+E ++ E G TAL +A Sbjct: 109 RGGLTALHMAAGYVRPEVVEALVELGADIEV-----EDERGLTALELARE 153 >3T9K-A nrPDB Length = 390 Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 64/160 (40%), Gaps = 15/160 (9%) Query: 17 VAPRLSPVRVWPRPQAPKEPALHPMGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQ 76 + PR +R P P + +LHP G L + G L ++ A D Sbjct: 176 IRPRPGDLRSKPEPPSEDLGSLHP-GALLFRASGHPPSL-------PTMADALAHGAD-V 226 Query: 77 NLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM 136 N + + +PL+ A N + A LL+ V+Q + G LH A + + A Sbjct: 227 NWVNGGQDNATPLIQATAANSLLACEFLLQ-NGANVNQADSAGRGPLHHATILGHTGLAC 285 Query: 137 VLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + ++ +L + EG+ L IA+ N ++V L Sbjct: 286 LFLKRGADLG-----ARDSEGRDPLTIAMETANADIVTLL 320 Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 40/117 (34%), Gaps = 16/117 (13%) Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCN 198 + ++ + + T L A ++ LL A+V+ + Sbjct: 220 LAHGADVNWVNGGQDN---ATPLIQATAANSLLACEFLLQNGANVNQADSA--------- 267 Query: 199 LIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 G PL A + + L ++ GAD+ A+DS G L I + N + Sbjct: 268 ----GRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320 Score = 53.2 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 47/143 (32%), Gaps = 23/143 (16%) Query: 177 LARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLG 236 LA A V+ G PL A NS L+++GA++ DS G Sbjct: 220 LAHGADVNWVNGGQ-----------DNATPLIQATAANSLLACEFLLQNGANVNQADSAG 268 Query: 237 NTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMF 296 LH + + AC + + G L + +G P +A N + Sbjct: 269 RGPLHHATILGHTGLAC-------LFLKRGADL----GARDSEGRDPLTIAMETANADIV 317 Query: 297 QHL-MQKRKHTQWTYGPLTSTLY 318 L + K + + G Y Sbjct: 318 TLLRLAKMREAEAAQGQAGDETY 340 >3DEO-A nrPDB Length = 183 Score = 63.9 bits (154), Expect = 3e-10, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 18/124 (14%) Query: 120 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLAR 179 ET AA + +A L+E + + G+TAL + VR L Sbjct: 45 ETPWWTAARKADEQALSQLLE------DRDVDAVDENGRTALLFVAGLGSDKCVRLLAEA 98 Query: 180 RASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTV 239 A + R + G L AA E+V L+E GADI +D G T Sbjct: 99 GADLDHRD------------MRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTA 146 Query: 240 LHIL 243 L + Sbjct: 147 LELA 150 Score = 62.4 bits (150), Expect = 7e-10, Method: Composition-based stats. Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 6/103 (5%) Query: 85 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +E+P AA+ D QAL++LL ED V G TAL A + + +L EA + Sbjct: 44 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA 187 L M G TALH+A +V AL+ A + Sbjct: 102 LDHRDMR----GGLTALHMAAGYVRPEVVEALVELGADIEVED 140 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 30/110 (27%), Positives = 40/110 (36%), Gaps = 18/110 (16%) Query: 69 WAQSR--DEQNLLQQKRIWE---------SPLLLAAKDNDVQALNKLLKYEDCKVHQRGA 117 W +R DEQ L Q + + LL A +LL + R Sbjct: 49 WTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLG-SDKCVRLLAEAGADLDHRDM 107 Query: 118 MG-ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVV 166 G TALH+AA Y E L+E ++ E G TAL +A Sbjct: 108 RGGLTALHMAAGYVRPEVVEALVELGADIEV-----EDERGLTALELARE 152 >2KXP-C nrPDB Length = 118 Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 38/120 (31%), Gaps = 18/120 (15%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 A +L+ + ++ L G+ LH A + ++ LL + A Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDV-----NRTLEGGRKPLHYAADCGQLEILEFLLLKGAD 60 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 ++A PL A V+LL+ GAD + G T L Sbjct: 61 INAPDKHHI-------------TPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEA 107 Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 39/97 (40%), Gaps = 6/97 (6%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + + A K+ D+ + + + V++ G LH AA LE L+ ++ Sbjct: 3 DKEFMWALKNGDLDEVKDYV-AKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADI 61 Query: 146 VFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 + T L AV +++ V+ LL++ A Sbjct: 62 -----NAPDKHHITPLLSAVYEGHVSCVKLLLSKGAD 93 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 50/138 (36%), Gaps = 28/138 (20%) Query: 164 AVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 A+ N +++ V+ +A+ V+ G G PL +AA EI+ L+ Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEG-------------GRKPLHYAADCGQLEILEFLL 55 Query: 224 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTP 283 GADI A D T L + + + LLLS V GLT Sbjct: 56 LKGADINAPDKHHITPLLSAVYEGH----VSCVKLLLSKGAD-------KTVKGPDGLTA 104 Query: 284 FKLAGVEGNTVMFQHLMQ 301 + + + L+Q Sbjct: 105 LEATDNQA----IKALLQ 118 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 37/114 (32%), Gaps = 12/114 (10%) Query: 209 FAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDH 268 +A + V+ + G D+ G LH ++ LL G Sbjct: 8 WALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQ----LEILEFLLLK---GAD 60 Query: 269 LQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTE 322 + P+ +TP A EG+ + L+ K GP T + T+ Sbjct: 61 INA----PDKHHITPLLSAVYEGHVSCVKLLLSKGADKTV-KGPDGLTALEATD 109 >6BPQ-A nrPDB Length = 950 Score = 59.3 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 46/235 (19%), Positives = 90/235 (38%), Gaps = 31/235 (13%) Query: 429 ELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISAS 488 E++ + I+L EV + G F + + + + +S Sbjct: 643 EIILYVLVFILLCDEVRQWYMNGSKYFSDLWNVMDTLAIFYFIAGIVFR----LHSDESS 698 Query: 489 GEVVPMSFAL--VLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 546 + F L ++ +++ + LGP IM+Q+M+ D+ F +L AV ++ F Sbjct: 699 WYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMI-DVFFFLFLFAVWMVAFGV 757 Query: 547 AFYIIFQTED----------------------PEEL-GHFYDYPMALFSTFELFLTIIDG 583 A I + + P+++ G Y++ FS E ++ Sbjct: 758 ARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDIDGTTYNFDHCTFSGNESKPLCVEL 817 Query: 584 PANYNVDLP-FMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQI 637 AN P ++ + + +L++NLL+AM G T V D++W+ Q Sbjct: 818 DANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQR 872 >6BWF-A nrPDB Length = 954 Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 61/156 (39%), Gaps = 21/156 (13%) Query: 496 FALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTE 555 ++ + ++ F Q GP+ +MI KM+ ++ +MA+V+L F I Sbjct: 621 LNIIFWYVRLLDFLAVNQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILYPH 679 Query: 556 DPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDL--------------PFMYSITYAA 601 + + +A F + I Y +D+ ++ A Sbjct: 680 EE------PSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAV 733 Query: 602 FAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQI 637 + + ++M+NLLIA + + +V + +W+ Q Sbjct: 734 YLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQR 769 >6DJS-A nrPDB Length = 676 Score = 55.9 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 56/159 (35%), Gaps = 23/159 (14%) Query: 86 ESPLLLAAKDNDVQALNKLLK-YEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 144 E L AA+ ++ + K+L+ + V+ MG+ AL +A ++LE +L++ Sbjct: 45 EERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLK---- 100 Query: 145 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRA------------SVSARATGTAF 192 L AL +A+ + +V A+L + Sbjct: 101 ------KENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYA 154 Query: 193 RRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRA 231 P+ AA E+V +L+ GA I Sbjct: 155 YDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIER 193 >4BSZ-B nrPDB Length = 202 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 E TALH+A N ++ VR +L + ++ AF G L +A+ Sbjct: 47 KESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKT---GNTALHWAS 103 Query: 212 CVNSEEIVRLLI-EHGADIRAQDSLGNTVLHILILQPNKT 250 ++V+LL E+ AD ++ G H I + + Sbjct: 104 LNGKLDVVKLLCDEYEADPFIRNKFG----HDAIFEAENS 139 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 10/104 (9%) Query: 89 LLLAAKDNDVQALN----KLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME---- 140 ++L A+ D+ +L L+ E + TALH+AA ++E ++E Sbjct: 18 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSR 77 Query: 141 -AAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALL-ARRAS 182 + E + + G TALH A +N +++V+ L A Sbjct: 78 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEAD 121 Score = 37.8 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 34/108 (31%), Gaps = 20/108 (18%) Query: 205 HPLSFAACVNSEEIVRLLIE-----HGAD-----IRAQDSLGNTVLHILILQPNKTFACQ 254 L AA E VR ++E + A+ + + GNT LH L Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK- 112 Query: 255 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 302 LL + D + N G A G + + ++K Sbjct: 113 ----LLCDEYEADPF-----IRNKFGHDAIFEAENSGKEEVETYFLKK 151 >5U0K-A nrPDB Length = 141 Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 5/105 (4%) Query: 76 QNLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAA 135 +NL Q LL AA DV AL + + Q+ TALH+AA ++E Sbjct: 16 ENLYFQSMKTVVNLLFAAYSGDVSALRRFAL-SAMDMEQKDYDSRTALHVAAAEGHIEVV 74 Query: 136 MVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARR 180 L+EA P + + G L AV ++ +V+ L + Sbjct: 75 KFLIEACK---VNPFAKDRW-GNIPLDDAVQFNHLEVVKLLQDYQ 115 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 17/100 (17%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA ++ A L M + Y+ +TALH+A ++ +V+ L+ Sbjct: 29 LLFAAYSGDVSALRRF-----ALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE---- 79 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLL 222 A + +P +G PL A N E+V+LL Sbjct: 80 --------ACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 32/95 (33%), Gaps = 3/95 (3%) Query: 166 VNQNMNLVRALL--ARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI 223 Q+M V LL A VSA Y L AA E+V+ LI Sbjct: 19 YFQSMKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLI 78 Query: 224 EH-GADIRAQDSLGNTVLHILILQPNKTFACQMYN 257 E + A+D GN L + + + + Sbjct: 79 EACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQD 113 >1D9S-A nrPDB Length = 136 Score = 53.5 bits (127), Expect = 4e-07, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 49/141 (34%), Gaps = 18/141 (12%) Query: 112 VHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMN 171 +H G + L AA +E L+EA + + G+ + + ++ + Sbjct: 5 IHMLGGSSDAGLATAAARGQVETVRQLLEAGADP-----NALNRFGRRPIQV-MMMGSAQ 58 Query: 172 LVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRA 231 + LL A + T R P+ AA + + +L GA + Sbjct: 59 VAELLLLHGAEPNCADPATLTR------------PVHDAAREGFLDTLVVLHRAGARLDV 106 Query: 232 QDSLGNTVLHILILQPNKTFA 252 D+ G + + Q ++ A Sbjct: 107 CDAWGRLPVDLAEEQGHRDIA 127 Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 37/103 (35%), Gaps = 11/103 (10%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L+ AA E VR L+E GAD A + G + ++++ + Q+ LLL + Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMM-----GSAQVAELLLLHGAEP 70 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWT 309 + P L P A EG L + Sbjct: 71 NCADPATLTR------PVHDAAREGFLDTLVVLHRAGARLDVC 107 Score = 32.7 bits (73), Expect = 0.67, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVL 138 P+ AA++ + L L + ++ A G + +A + + A L Sbjct: 81 PVHDAAREGFLDTLVVLHRA-GARLDVCDAWGRLPVDLAEEQGHRDIARYL 130 >5OEO-C nrPDB Length = 73 Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 6/54 (11%) Query: 695 GSEDLDKDSVEK----LELGCPFSPHLSLPMPSVSRSTSRSSAN--WERLRQGT 742 ED + EK E G L+LP S+SR+ S+SS++ WE LRQ T Sbjct: 3 DKEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSSSHRGWEILRQNT 56 >1DCQ-A nrPDB Length = 278 Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 7/93 (7%) Query: 86 ESPLLLAAKDNDVQALNKL--LKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 143 E+ L LA + D +L+ + L + ++ G TALH L DN E +L+ Sbjct: 170 ETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKA 229 Query: 144 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRAL 176 + G+T L IA ++ + L Sbjct: 230 SIEIA-----NESGETPLDIAKRLKHEHCEELL 257 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 45/113 (39%), Gaps = 20/113 (17%) Query: 138 LMEAAPELV----FEPMTSELYEGQTALHIAV---VNQNMNLVRALLARRASVSARATGT 190 L++A + V P+ + +TALH+AV ++++V L+ ++ + Sbjct: 146 LLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGK- 204 Query: 191 AFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 G L + ++ E ++LL+ A I + G T L I Sbjct: 205 ------------GSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIA 245 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 49/138 (35%), Gaps = 27/138 (19%) Query: 90 LLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAAL---YDNLEAAMVLMEAAPELV 146 LL A + V K+ + ETALH+A +L L++ + L Sbjct: 146 LLQAYADGVDLTEKIPLANGHEPD------ETALHLAVRSVDRTSLHIVDFLVQNSGNL- 198 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 206 + +G TALH + N ++ LL +AS+ GE P Sbjct: 199 ----DKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANES-------------GETP 241 Query: 207 LSFAACVNSEEIVRLLIE 224 L A + E LL + Sbjct: 242 LDIAKRLKHEHCEELLTQ 259 Score = 36.2 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 30/87 (34%), Gaps = 14/87 (16%) Query: 204 EHPLSFAA---CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 260 E L A S IV L+++ ++ Q G+T LH L N LL Sbjct: 170 ETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLK-----LL 224 Query: 261 SYDRHGDHLQPLDLVPNHQGLTPFKLA 287 + + N G TP +A Sbjct: 225 LRGKASI------EIANESGETPLDIA 245 Score = 30.8 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 1/78 (1%) Query: 77 NLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM 136 NL +Q + L ++ + L LL+ + + GET L IA + Sbjct: 197 NLDKQTGKGSTALHYCCLTDNAECLKLLLRGK-ASIEIANESGETPLDIAKRLKHEHCEE 255 Query: 137 VLMEAAPELVFEPMTSEL 154 +L +A + E Sbjct: 256 LLTQALSGRFNSHVHVEY 273 >3LVQ-E nrPDB Length = 497 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 44/116 (37%), Gaps = 21/116 (18%) Query: 161 LHIAVVNQN---MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEE 217 LH+AV N + LV ++ + A+A G L +AA N + Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYNQPD 221 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLD 273 ++LL++ A + + G T L I + +K LL + G PL Sbjct: 222 CLKLLLKGRALVGTVNEAGETALDIARKKHHKE-----CEELLEQAQAGTFAFPLH 272 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 7/99 (7%) Query: 89 LLLAAKDNDVQALNKL--LKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 L LA K + +L + + + + A G TALH AALY+ + +L++ + Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA 185 + G+TAL IA + L +A A Sbjct: 235 -----TVNEAGETALDIARKKHHKECEELLEQAQAGTFA 268 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 1/69 (1%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + L AA N L LLK V GETAL IA + E +L +A Sbjct: 208 NTALHYAALYNQPDCLKLLLKGR-ALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT 266 Query: 146 VFEPMTSEL 154 P+ + Sbjct: 267 FAFPLHVDY 275 >2B0O-E nrPDB Length = 301 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 44/116 (37%), Gaps = 21/116 (18%) Query: 161 LHIAVVNQN---MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEE 217 LH+AV N + LV ++ + A+A G L +AA N + Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYNQPD 240 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLD 273 ++LL++ A + + G T L I + +K LL + G PL Sbjct: 241 CLKLLLKGRALVGTVNEAGETALDIARKKHHKE-----CEELLEQAQAGTFAFPLH 291 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 7/99 (7%) Query: 89 LLLAAKDNDVQALNKL--LKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 L LA K + +L + + + + A G TALH AALY+ + +L++ + Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253 Query: 147 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSA 185 + G+TAL IA + L +A A Sbjct: 254 -----TVNEAGETALDIARKKHHKECEELLEQAQAGTFA 287 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 1/69 (1%) Query: 86 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + L AA N L LLK V GETAL IA + E +L +A Sbjct: 227 NTALHYAALYNQPDCLKLLLKGR-ALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT 285 Query: 146 VFEPMTSEL 154 P+ + Sbjct: 286 FAFPLHVDY 294 >2A5E-A nrPDB Length = 156 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 46/130 (35%), Gaps = 18/130 (13%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA +E L+EA L P + G+ + + ++ + + LL A Sbjct: 16 LATAAARGRVEEVRALLEAGA-LPNAPNS----YGRRPIQV-MMMGSARVAELLLLHGAE 69 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 + T R P+ AA + + +L GA + +D+ G + + Sbjct: 70 PNCADPATLTR------------PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 Query: 243 LILQPNKTFA 252 ++ A Sbjct: 118 AEELGHRDVA 127 Score = 42.8 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 53/145 (36%), Gaps = 16/145 (11%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L+ AA E VR L+E GA A +S G + ++++ + ++ LLL + Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-----GSARVAELLLLHGAEP 70 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEG--NTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEID 324 + P L P A EG +T++ H R + +G L DL E Sbjct: 71 NCADPATLTR------PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPV---DLAEEL 121 Query: 325 SSGDEQSLLELIITTKKREARQILD 349 D L + +D Sbjct: 122 GHRDVARYLRAAAGGTRGSNHARID 146 Score = 32.4 bits (72), Expect = 0.87, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 88 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVL 138 P+ AA++ + L L + ++ R A G + +A + + A L Sbjct: 81 PVHDAAREGFLDTLVVLHRA-GARLDVRDAWGRLPVDLAEELGHRDVARYL 130 >5U0J-A nrPDB Length = 140 Score = 45.8 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 32/108 (29%), Gaps = 1/108 (0%) Query: 175 ALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEH-GADIRAQD 233 A VSA Y L AA E+V+ L+E + +D Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 88 Query: 234 SLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGL 281 NT + + + + + Y GD + H+ L Sbjct: 89 RWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNL 136 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 32/83 (38%) Query: 77 NLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM 136 ++ Q+ + L +AA + V+ + LL+ + T + A + + + Sbjct: 49 DMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFK 108 Query: 137 VLMEAAPELVFEPMTSELYEGQT 159 +L E + + + E QT Sbjct: 109 ILQEYQVQYTPQGDSDNGKENQT 131 Score = 43.1 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 41/115 (35%), Gaps = 17/115 (14%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA ++ A L M Y+ +TALH+A ++ +V+ LL Sbjct: 28 LLFAAYTGDVSALRRF-----ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE---- 78 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGN 237 A + +P + P+ A ++ ++L E+ Q N Sbjct: 79 --------ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 125 Score = 33.9 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 46/126 (36%), Gaps = 21/126 (16%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L FAA +R D+ +D T LH+ + + ++ LL + Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGH----VEVVKFLLEACK-- 81 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSS 326 + P + TP A G+ +F+ ++Q+ Q Y P + D+ Sbjct: 82 --VNPFPK--DRWNNTPMDEALHFGHHDVFK-ILQE---YQVQYTPQGDS-------DNG 126 Query: 327 GDEQSL 332 + Q++ Sbjct: 127 KENQTV 132 >5Z1W-A nrPDB Length = 566 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 46/308 (14%), Positives = 107/308 (34%), Gaps = 34/308 (11%) Query: 343 EARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSP 402 + ++ L W G + ++Y I F CI R + + Sbjct: 212 PGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLF---CILRLVVEFPATGGTI 268 Query: 403 RDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRF------- 455 + KL++ Y+ D + E+V + ++ E+ +I + Sbjct: 269 PSWQIRTVKLIR--YVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNIL 326 Query: 456 ----FGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSF-----------ALVL 500 +I+ FH+ T L+ +++ + ++F L Sbjct: 327 DLVVILLSIVAVGFHI-FRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFF 385 Query: 501 GWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEEL 560 W + + + + + + + D++ F + +V +A Y++F T+ Sbjct: 386 AWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAIMFFIVFFAYAQLGYLLFGTQVEN-- 442 Query: 561 GHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGD 620 F + +F+ F + L D A N + + + + + ++LN+ +A++ D Sbjct: 443 --FSTFVKCIFTQFRIILGDFDYNAIDNAN-RILGPVYFVTYVFFVFFVLLNMFLAIIND 499 Query: 621 THWRVAHE 628 T+ V E Sbjct: 500 TYSEVKEE 507 >5UQE-A nrPDB Length = 520 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 28/97 (28%), Gaps = 1/97 (1%) Query: 175 ALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEH-GADIRAQD 233 A VSA Y L AA E+V+ L+E + +D Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 481 Query: 234 SLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQ 270 NT + + + + + Y GD Sbjct: 482 RWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 518 Score = 43.1 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 41/115 (35%), Gaps = 17/115 (14%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 182 L AA ++ A L M Y+ +TALH+A ++ +V+ LL Sbjct: 421 LLFAAYTGDVSALRRF-----ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE---- 471 Query: 183 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGN 237 A + +P + P+ A ++ ++L E+ Q N Sbjct: 472 --------ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 518 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 29/77 (37%) Query: 77 NLLQQKRIWESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAM 136 ++ Q+ + L +AA + V+ + LL+ + T + A + + + Sbjct: 442 DMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFK 501 Query: 137 VLMEAAPELVFEPMTSE 153 +L E + + + Sbjct: 502 ILQEYQVQYTPQGDSDN 518 Score = 33.1 bits (74), Expect = 0.51, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 40/110 (36%), Gaps = 14/110 (12%) Query: 207 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 266 L FAA +R D+ +D T LH+ + + ++ LL + Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGH----VEVVKFLLEACK-- 474 Query: 267 DHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTST 316 + P + TP A G+ +F+ ++Q+ Q Y P + Sbjct: 475 --VNPFPK--DRWNNTPMDEALHFGHHDVFK-ILQE---YQVQYTPQGDS 516 >6DU8-A nrPDB Length = 805 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 51/352 (14%), Positives = 119/352 (33%), Gaps = 39/352 (11%) Query: 304 KHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK-----KREARQILDQTPVKELVS 358 K Q +GP T + D G L + + ++ L Sbjct: 231 KEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQE 290 Query: 359 LKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYM 418 W G + ++Y I F C+ R + + + KL++ Y+ Sbjct: 291 GLWLDRGTRVVFIDFSVYNANINLF---CVLRLVVEFPATGGAIPSWQIRTVKLIR--YV 345 Query: 419 TPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRF-----------FGQTILGGPFHV 467 + D + E++ + ++ E+ ++ + +I+ FH+ Sbjct: 346 SNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHI 405 Query: 468 LIITYAFMVLVTMVMRLISASGEVVPMSF-----------ALVLGWCNVMYFARGFQMLG 516 T L+ +++ + + ++F L W + + + + Sbjct: 406 -FRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMT 464 Query: 517 PFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFEL 576 + + + D++ F + +V +A Y++F T+ F + +F+ F + Sbjct: 465 QLSSTLARCA-KDILGFAVMFFIVFFAYAQLGYLLFGTQVEN----FSTFIKCIFTQFRI 519 Query: 577 FLTIIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE 628 L D A N + + + + ++LN+ +A++ DT+ V E Sbjct: 520 ILGDFDYNAIDNAN-RILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEE 570 >5UIL-A nrPDB Length = 405 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 43/99 (43%), Gaps = 9/99 (9%) Query: 157 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 216 G + + +A + N+ L++ L+++ A+++ R + +YF ++ L Sbjct: 311 GWSPVIVAAYHGNIELIKWLVSKGANINDRN-----YKGTTVAMYFKDYML----KSGDY 361 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 +++LI+ G D+ D TV L NK M Sbjct: 362 SGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQYM 400 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 47/116 (40%), Gaps = 12/116 (10%) Query: 185 ARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILI 244 RA F ++ +G P+ AA + E+++ L+ GA+I ++ G TV + Sbjct: 298 IRAKSILFEKN-----IYGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKGTTV---AM 349 Query: 245 LQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLM 300 + Y+ L G L + +++ T F GN + Q++M Sbjct: 350 YFKDYMLKSGDYSGLKMLIDLGLDLT----LTDYKDYTVFDYLEKSGNKNLLQYMM 401 >5T4D-A nrPDB Length = 510 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 12/130 (9%) Query: 502 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELG 561 W + F + + + + + DL F + ++ L +A Y++F T+ + Sbjct: 378 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAYAQLAYLVFGTQVDD--- 433 Query: 562 HFYDYPMALFSTFELFLTIIDGPANY---NVDLPFMYSITYAAFAIIATLLMLNLLIAMM 618 F + +F+ F II G N+ + I + F ++LN+ +A++ Sbjct: 434 -FSTFQECIFTQFR----IILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAII 488 Query: 619 GDTHWRVAHE 628 DT+ V + Sbjct: 489 NDTYSEVKSD 498 >5EK0-A nrPDB Length = 296 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 37/207 (17%), Positives = 78/207 (37%), Gaps = 11/207 (5%) Query: 429 ELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISAS 488 E++ I + I+L + I R+ V R + P+ + + +V M + + + Sbjct: 60 EVLYWINVVFIILFTIEIILRIYVHR---ISFFKDPWSLFDFVVVIISIVGMFLADLIET 116 Query: 489 GEVVPMSFALV----LGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGF 544 V P F ++ +G + QM + +I + ++ LM + F Sbjct: 117 YFVSPTLFRVIRLARIGRI-LRLVTAVPQMRKIVSALIS--VIPGMLSVIALMTLFFYIF 173 Query: 545 ASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAI 604 A +F PE G + LF L + P+ + + F Sbjct: 174 AIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVF-FIPFIF 232 Query: 605 IATLLMLNLLIAMMGDTHWRVAHERDE 631 + T +M+NL++A++ D + + ++ Sbjct: 233 VVTFVMINLVVAIIVDAMAILNQKEEQ 259 >5WPT-A nrPDB Length = 592 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 87/211 (41%), Gaps = 18/211 (8%) Query: 432 TVIGAIIILLVEVPDIFRMG---VTRFFGQTILGGPFHVLIITYAFMVLVTMVMR----- 483 +++ ++ V ++R ++ + + G + +L++T + + VM+ Sbjct: 319 SLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWY-ILLVTSDVLTISGTVMKIGIEA 377 Query: 484 --LISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVI 541 L S + + + +L W V+ + F I ++ +MRFC +AV+ Sbjct: 378 KNLASYDVCSILLGTSTLLVWVGVIRYLTFFHKYNIL-IATLRVALPSVMRFCCCVAVIY 436 Query: 542 LGFASAFYIIFQTEDPEELGHFYDYPMALFSTF---ELFLTIIDGPANY-NVDLPFMYSI 597 LG+ +I+ + LFS ++F+T A + L +++S Sbjct: 437 LGYCFCGWIVLGPYHVK-FRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQ 495 Query: 598 TYA-AFAIIATLLMLNLLIAMMGDTHWRVAH 627 Y +F + ++L+L IA++ + + H Sbjct: 496 LYLYSFISLFIYMVLSLFIALITGAYDTIKH 526 >5MKE-A nrPDB Length = 968 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 12/130 (9%) Query: 502 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELG 561 W + F + + + + + DL F + ++ L +A Y++F T+ + Sbjct: 570 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAYAQLAYLVFGTQVDD--- 625 Query: 562 HFYDYPMALFSTFELFLTIIDGPANY---NVDLPFMYSITYAAFAIIATLLMLNLLIAMM 618 F + +F+ F II G N+ + I + F ++LN+ +A++ Sbjct: 626 -FSTFQECIFTQFR----IILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAII 680 Query: 619 GDTHWRVAHE 628 DT+ V + Sbjct: 681 NDTYSEVKSD 690 >4XD0-A nrPDB Length = 417 Score = 38.5 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 44/104 (42%), Gaps = 9/104 (8%) Query: 152 SELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAA 211 + + G + + IA + NM+++ L+++ +++ R + +YF ++ L Sbjct: 319 EKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRN-----YKGTTVAMYFKDYMLRSGN 373 Query: 212 CVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 E ++ L G D+ +D+ G +V + N M Sbjct: 374 YTGLENLINL----GLDLFLKDNEGLSVFDYMRKNKNIELFNFM 413 Score = 36.6 bits (83), Expect = 0.041, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 39/101 (38%), Gaps = 15/101 (14%) Query: 203 GEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVL----HILILQPNKTFACQMYNL 258 G P+ AA + +++ L+ G +I ++ G TV ++ N T + NL Sbjct: 324 GWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINL 383 Query: 259 LLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHL 299 L + +++GL+ F N +F + Sbjct: 384 GLDL-----------FLKDNEGLSVFDYMRKNKNIELFNFM 413 >4DXW-A nrPDB Length = 229 Score = 37.8 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 9/103 (8%) Query: 521 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELF-LT 579 ++++ F L+ F L +A+ I+F +DP G + LF L Sbjct: 129 SVRRVFFVSLLLFIILYI-----YATMGAILFGNDDPSRWGDLGISLITLFQVLTLSSWE 183 Query: 580 IIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTH 622 + P ++Y + +F II ++ +LNL+IA++ D Sbjct: 184 TVMLPMQEIYWWSWVY---FFSFIIICSITILNLVIAILVDVV 223 >6D1W-A nrPDB Length = 740 Score = 37.8 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 12/130 (9%) Query: 502 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELG 561 W + F + + + + + DL F + ++ L +A Y++F T+ + Sbjct: 518 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMPFIIFLAYAQLAYLVFGTQVDD--- 573 Query: 562 HFYDYPMALFSTFELFLTIIDGPANY---NVDLPFMYSITYAAFAIIATLLMLNLLIAMM 618 F + +F+ F II G N+ + I + F ++LN+ +A++ Sbjct: 574 -FSTFQECIFTQFR----IILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAII 628 Query: 619 GDTHWRVAHE 628 DT+ V + Sbjct: 629 NDTYSEVKSD 638 >6E7Z-A nrPDB Length = 580 Score = 37.0 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 36/191 (18%), Positives = 77/191 (40%), Gaps = 14/191 (7%) Query: 449 RMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMR-------LISASGEVVPMSFALVLG 501 R V + + +++L++T + + +M+ L S + + + +L Sbjct: 338 RGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLV 397 Query: 502 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELG 561 W V+ + F I ++ +MRFC +AV+ LG+ +I+ + Sbjct: 398 WVGVIRYLTFFHNYNIL-IATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVK-FR 455 Query: 562 HFYDYPMALFSTF---ELFLTIIDGPANY-NVDLPFMYSITYA-AFAIIATLLMLNLLIA 616 LFS ++F+T A L +++S Y +F + ++L+L IA Sbjct: 456 SLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIA 515 Query: 617 MMGDTHWRVAH 627 ++ + + H Sbjct: 516 LITGAYDTIKH 526 >6AYG-A nrPDB Length = 558 Score = 37.0 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 31/164 (18%), Positives = 68/164 (41%), Gaps = 18/164 (10%) Query: 473 AFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMR 532 + + + L S + + + +L W V+ + F + +Q +++R Sbjct: 361 SILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAA-LPNVIR 419 Query: 533 FCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGP-------- 584 FC A++ LG+ +I+ LG ++D +L E ++I+G Sbjct: 420 FCCCAAMIYLGYCFCGWIV--------LGPYHDKFRSLNMVSECLFSLINGDDMFATFAK 471 Query: 585 ANYNVDLPFMYSITYA-AFAIIATLLMLNLLIAMMGDTHWRVAH 627 L +++S Y +F + ++L+L IA++ DT+ + Sbjct: 472 MQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQ 515 >4GX0-A nrPDB Length = 565 Score = 36.6 bits (83), Expect = 0.041, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 31/81 (38%) Query: 531 MRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVD 590 ++ L +L A+ IF+ G Y + ++ T + T+ G + D Sbjct: 17 LKVLLLYCAFLLVMLLAYASIFRYLMWHLEGRAYSFMAGIYWTITVMTTLGFGDITFESD 76 Query: 591 LPFMYSITYAAFAIIATLLML 611 ++++ +I ++L Sbjct: 77 AGYLFASIVTVSGVIFLDIIL 97 >3RVY-A nrPDB Length = 285 Score = 36.2 bits (82), Expect = 0.060, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 69/199 (34%), Gaps = 15/199 (7%) Query: 419 TPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLV 478 T K ++ G T+ I+I + + I R+ V R + P+ + F+V + Sbjct: 51 TSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHR---ISFFKDPWSLFDF---FVVAI 104 Query: 479 TMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMA 538 ++V V L QM + +I + ++ LM Sbjct: 105 SLVPTSSGFEILRVLRVLRL------FRLVTAVPQMRKIVSALIS--VIPGMLSVIALMT 156 Query: 539 VVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSIT 598 + FA +F PE G + LF L + P+ + Sbjct: 157 LFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVF- 215 Query: 599 YAAFAIIATLLMLNLLIAM 617 + F + T +M+NL++A+ Sbjct: 216 FIPFIFVVTFVMINLVVAI 234 >6BWI-A nrPDB Length = 977 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 59/164 (35%), Gaps = 40/164 (24%) Query: 513 QMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFS 572 + LGP +++ KM+ D+ F + + V ++ + A + + D D+P L Sbjct: 715 KQLGPKIVIVSKMM-KDVFFFLFFLGVWLVAYGVATEGLLRPRDS-------DFPSILRR 766 Query: 573 TF-ELFLTIIDGPANYNVDLPFM-------------------------------YSITYA 600 F +L I ++D+ M + Sbjct: 767 VFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLV 826 Query: 601 AFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVML 644 F ++A +L++NLLIAM T +V D W+AQ Sbjct: 827 IFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREF 870 >6N4I-A nrPDB Length = 288 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 56/146 (38%), Gaps = 7/146 (4%) Query: 473 AFMVLVTMV-MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLM 531 + +V +++V + L G V SF L+ + V QM + +I + ++ Sbjct: 98 SLIVTLSLVELFLADVEGLSVLRSFRLLRVFRLVTAVP---QMRKIVSALIS--VIPGML 152 Query: 532 RFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDL 591 LM + FA +F PE G + LF L + Sbjct: 153 SVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVY 212 Query: 592 PFMYSITYAAFAIIATLLMLNLLIAM 617 P+ + + F + T +M+NL++A+ Sbjct: 213 PYAWVF-FIPFIFVVTFVMINLVVAI 237 >4LTR-A nrPDB Length = 152 Score = 33.1 bits (74), Expect = 0.44, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 48/126 (38%), Gaps = 5/126 (3%) Query: 516 GPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFE 575 GP + + + I G + L+ V+ FA +F PE G LF Sbjct: 1 GPSSPSLLRAIPG-IAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMT 59 Query: 576 LFLTIIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRV---AHERDEL 632 L + P+ + I + +F ++++ +LNL I ++ ++ A + + Sbjct: 60 LESWSMGIARPVIEAYPWAW-IYFVSFILVSSFTVLNLFIGIIIESMQSAGWEAEDAKRI 118 Query: 633 WRAQIV 638 + Q Sbjct: 119 EQEQRA 124 >3S0X-A nrPDB Length = 237 Score = 32.7 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 433 VIGAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVV 492 +IGA+ +++ V D + + + F VL Y+ + L+ + + S SG V+ Sbjct: 12 IIGALGLIIASVQDFRSREIEDYIWIFL--AVFGVLFAIYSSITLLDYSILINSISGFVI 69 Query: 493 PMSFALVL 500 ++ Sbjct: 70 CFILGYMM 77 >5E1J-A nrPDB Length = 741 Score = 31.2 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 7/104 (6%) Query: 526 IFGDLMRFCWLMAVVILGFASA----FYIIFQTEDPEELGHFYDYPMALFSTFELFL--- 578 IF L +C + V G +A + ED L +F DYP + + F L + Sbjct: 572 IFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGN 631 Query: 579 TIIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTH 622 + + ++ + + +F +I LL+LNL++A + + Sbjct: 632 WQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAF 675 >3CO4-A nrPDB Length = 312 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 11/100 (11%) Query: 42 GLSLPKEKGLIL-CLWSKFCRWFQRRESWAQSRDEQNLLQQKR--IWESPLLLAAKDNDV 98 GL L KEK +++ C + RW W Q D NL+ R + P+ A+ D+ V Sbjct: 132 GLYLAKEKNMLMTCAVNS--RWLNYGTEWEQYFDYINLMSYDRGAFTDKPVQHASYDDFV 189 Query: 99 QALNKLLKYEDCKVHQRGAM--GETALHIAALYDNLEAAM 136 K LKY + + + G + + ++L+ A+ Sbjct: 190 ----KDLKYWNEQCRASKSKIVGGLPFYGYSWEESLQGAV 225 >2GBW-A nrPDB Length = 454 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 37/194 (19%), Positives = 60/194 (30%), Gaps = 35/194 (18%) Query: 182 SVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGAD------IRAQDSL 235 V A F R+ L + P ++++ H +D I + Sbjct: 24 DVYALEIERIFSRAWLMLGHESLVPKPGDFITTYMAEDKVILSHQSDGTFRAFINSCSHR 83 Query: 236 GNTVLHILILQPN-KTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTV 294 GN + H N K F C Y+ + PL+ H L KLA Sbjct: 84 GNQICHA--DSGNAKAFVCN-YHGWVFGQDGSLVDVPLESRCYHNSLDKQKLAAKSVRVE 140 Query: 295 MFQHLMQKRKHTQWTYGPLTSTLYD-LTE----IDSSGDEQ-SLLELIITTKKREARQIL 348 ++ + P +L D L E +D+ + +EL+ Sbjct: 141 TYK------GFIFGCHDPEAPSLEDYLGEFRYYLDTIWEGAGGGMELLG----------- 183 Query: 349 DQTPVKELVSLKWK 362 P+K L+ WK Sbjct: 184 --PPMKSLLQCNWK 195 >5AEM-A nrPDB Length = 447 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 32/144 (22%), Positives = 46/144 (31%), Gaps = 9/144 (6%) Query: 57 SKFCRWFQRRES---WAQSRDEQNLLQQKRIWES---PLLLAAKDNDVQALNKLLKYEDC 110 K RW QRRES W D+ +R S LL A K+ + Sbjct: 263 KKCARWIQRRESQTFWDHVPDDSE-FDNRRFKNSTFDSLLAAEKEKSYNIPIDIRVRLGL 321 Query: 111 KVHQRGAMGETALHIAALYDNL--EAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQ 168 + E H LYD + A + EAA L E + T L + Sbjct: 322 LRLNTDNLVEALNHFQCLYDETFSDVADLYFEAATALTRAEKYKEAIDFFTPLLSLEEWR 381 Query: 169 NMNLVRALLARRASVSARATGTAF 192 ++ + L + + T F Sbjct: 382 TTDVFKPLARCYKEIESYETAKEF 405 >4FZS-A nrPDB Length = 224 Score = 30.4 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 15/36 (41%), Positives = 23/36 (63%) Query: 64 QRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQ 99 QR ++W + +D Q LQ+KR E+ LL A K + +Q Sbjct: 114 QRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQ 149 >5HKD-A nrPDB Length = 152 Score = 30.0 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 2/109 (1%) Query: 516 GPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFE 575 GP + + + I G + L+ V+ FA +F PE G LF Sbjct: 1 GPSSPSLLRAIPG-IAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMT 59 Query: 576 LFLTIIDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWR 624 L + P+ + I + +F ++++ +LNL I ++ ++ Sbjct: 60 LESWSMGIARPVIEAYPWAW-IYFVSFILVSSFTVLNLFIGIIIESMQS 107 >4HBK-A nrPDB Length = 344 Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 48/132 (36%), Gaps = 8/132 (6%) Query: 223 IEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQ--PLDLVPNHQG 280 ++HG D+ DS G L + + ++ + L + + + H Sbjct: 149 LKHGGDLFPTDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCR 208 Query: 281 LTPFKLA----GVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELI 336 + P L N + ++ Q T Y PL S + +++ + +LE+ Sbjct: 209 IKPANLQIEIHANFPNIKLVEYA-QSVGLTVTAYAPLGSPAHSPGKVNLLT-KPCVLEIA 266 Query: 337 ITTKKREARQIL 348 KK A+ +L Sbjct: 267 HRHKKTPAQVLL 278 >2FT0-A nrPDB Length = 235 Score = 29.3 bits (64), Expect = 6.9, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 20/47 (42%) Query: 141 AAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARA 187 A EL+ + G+T L +A N ++ + A+V + A Sbjct: 184 AGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTA 230 >1Y1U-A nrPDB Length = 585 Score = 28.9 bits (63), Expect = 8.3, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 4/69 (5%) Query: 622 HWRVAHERDELWRAQIVATTVMLERKLPRCLWPR-SGICGREYGLGD---RWFLRVEDRQ 677 + L + T ++ + + + +G G G D W ++ + Sbjct: 100 VELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEII 159 Query: 678 DLNRQRIQR 686 NRQ+I+R Sbjct: 160 WQNRQQIRR 168 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.317 0.132 0.360 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,300,276 Number of Sequences: 36641 Number of extensions: 1102194 Number of successful extensions: 4592 Number of sequences better than 10.0: 103 Number of HSP's better than 10.0 without gapping: 134 Number of HSP's successfully gapped in prelim test: 46 Number of HSP's that attempted gapping in prelim test: 3130 Number of HSP's gapped (non-prelim): 486 length of query: 765 length of database: 10,336,785 effective HSP length: 105 effective length of query: 660 effective length of database: 6,489,480 effective search space: 4283056800 effective search space used: 4283056800 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.2 bits) S2: 63 (28.9 bits)