BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9FWR4 (213 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5ELG-A nrPDB 433 e-122 5LOL-A nrPDB 338 1e-93 5N9U-A nrPDB 322 1e-88 5IQY-A nrPDB 289 5e-79 5D9W-A nrPDB 282 8e-77 2R5G-A nrPDB 89 1e-18 5Y7I-A nrPDB 87 4e-18 4K0G-A nrPDB 86 1e-17 2D2Z-A nrPDB 80 7e-16 3FY7-A nrPDB 73 1e-13 2YV7-A nrPDB 64 3e-11 4PQI-A nrPDB 63 9e-11 3LFL-A nrPDB 62 2e-10 3WD6-A nrPDB 59 2e-09 4QQ7-A nrPDB 59 2e-09 3RBT-A nrPDB 57 5e-09 3QAG-A nrPDB 57 5e-09 1FW1-A nrPDB 52 2e-07 5J5N-A nrPDB 50 7e-07 2CZ2-A nrPDB 50 8e-07 3UAR-A nrPDB 48 3e-06 4AGS-A nrPDB 47 6e-06 1E6B-A nrPDB 46 9e-06 4J2F-A nrPDB 44 6e-05 4CHS-A nrPDB 42 2e-04 2VO4-A nrPDB 42 2e-04 5ECL-B nrPDB 42 2e-04 3UBL-A nrPDB 42 3e-04 3NIV-A nrPDB 41 3e-04 4MPF-A nrPDB 41 4e-04 4YH2-A nrPDB 40 6e-04 3PR8-A nrPDB 38 0.003 2PMT-A nrPDB 38 0.004 2YV9-A nrPDB 37 0.008 3BBY-A nrPDB 37 0.008 4IGJ-A nrPDB 37 0.009 3VWX-A nrPDB 36 0.011 2GDR-A nrPDB 35 0.016 5ZWP-A nrPDB 35 0.018 6EP7-A nrPDB 34 0.037 3R2Q-A nrPDB 33 0.062 5F06-A nrPDB 33 0.094 4EAH-A nrPDB 33 0.11 4RI7-A nrPDB 33 0.13 5NR1-A nrPDB 32 0.16 4OXR-A nrPDB 32 0.19 6F05-A nrPDB 32 0.23 1JLV-A nrPDB 32 0.26 2JL4-A nrPDB 32 0.27 4PXO-A nrPDB 32 0.27 5EY6-A nrPDB 31 0.30 3QMX-A nrPDB 31 0.39 4PNG-A nrPDB 31 0.45 3TOT-A nrPDB 30 0.57 3M8N-A nrPDB 30 0.76 4B7G-A nrPDB 30 0.82 5F07-A nrPDB 30 1.0 1AW9-A nrPDB 29 1.4 1PN9-A nrPDB 29 1.6 2VCV-A nrPDB 29 1.7 3QH2-A nrPDB 29 1.7 3GH6-A nrPDB 28 1.9 3MAK-A nrPDB 28 2.1 3IBH-A nrPDB 28 2.3 2VCT-A nrPDB 28 2.7 3I6A-A nrPDB 28 2.9 1PL2-A nrPDB 28 3.0 1F2E-A nrPDB 28 3.0 4USS-A nrPDB 28 3.7 4IKH-A nrPDB 28 4.0 4M2B-A nrPDB 27 4.7 6BYC-A nrPDB 27 4.8 1F3B-A nrPDB 27 4.8 5F05-A nrPDB 27 8.4 2C3Q-A nrPDB 27 8.7 2IL3-A nrPDB 27 9.1 5F0G-A nrPDB 26 10.0 >5ELG-A nrPDB Length = 221 Score = 433 bits (1113), Expect = e-122, Method: Compositional matrix adjust. Identities = 213/213 (100%), Positives = 213/213 (100%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV Sbjct: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 Query: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE Sbjct: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 Query: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV Sbjct: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 Query: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP 213 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP Sbjct: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP 213 >5LOL-A nrPDB Length = 215 Score = 338 bits (867), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 161/212 (75%), Positives = 184/212 (86%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MAL+ICVK AVGAPD LGDCPFSQR LLTLEEK L YK HLIN+SDKPQWFLDISP+GKV Sbjct: 3 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 62 Query: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 PV+K+D KWV DSDVIVG+LEEKYP+P LKTP EFASVGS IFG F TFLKSKD+NDGSE Sbjct: 63 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 122 Query: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 AL+ ELEALENHLK+H GPF+AGE+++AVDLSLAPKLYHL+VALGH+K+WSVPES V Sbjct: 123 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 182 Query: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 NY K LFS +SFE TK +++ V++GW KVN Sbjct: 183 RNYAKALFSRESFENTKAKKEIVVAGWESKVN 214 >5N9U-A nrPDB Length = 218 Score = 322 bits (824), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 156/212 (73%), Positives = 182/212 (85%), Gaps = 1/212 (0%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MALEICVKAAVGAP+ LGDCPF QR LL+LEEK + YK HLINL DKPQWFL+ISP+GKV Sbjct: 1 MALEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKV 60 Query: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 PV+KIDDKWV DSDVIVGILEEK P+PPL TP EFASVGS IF +F FLKSKD NDG+E Sbjct: 61 PVVKIDDKWVADSDVIVGILEEKNPEPPLATPPEFASVGSKIFPSFVKFLKSKDPNDGTE 120 Query: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 ALL EL+AL+ HLK H GPFIAGE+++AVDLSLAPKLYHL+VALGHFK+W +P++ HV Sbjct: 121 QALLEELKALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHV 179 Query: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 NY+K LFS +SF+KT+ E++VI+GW PKVN Sbjct: 180 LNYIKLLFSRESFKKTRAAEEHVIAGWEPKVN 211 >5IQY-A nrPDB Length = 216 Score = 289 bits (740), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 141/213 (66%), Positives = 171/213 (80%), Gaps = 2/213 (0%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MA+E+CVKAAVGAPD LGDCPFSQR LLTLEEK +TY++ L++LS+KP+WFL ISP+GKV Sbjct: 4 MAVEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKV 63 Query: 61 PVLKIDD-KWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGS 119 PV D KW+ DSDVI ++EEK+P P L TP E+ASVGS IF +F FLKSKD++DGS Sbjct: 64 PVFNSGDGKWIADSDVITQVIEEKFPTPSLVTPPEYASVGSKIFPSFVKFLKSKDASDGS 123 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E ALL EL+AL+ HLK+H GP+I+GE VSA DLSL PKL+HLQVAL HFK W +PE+ Sbjct: 124 EKALLDELQALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTS 182 Query: 180 VHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 VH Y K LFS +SF KTK +Y+I+GWAPKVN Sbjct: 183 VHAYTKALFSRESFVKTKPANQYLIAGWAPKVN 215 >5D9W-A nrPDB Length = 230 Score = 282 bits (721), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 139/213 (65%), Positives = 165/213 (77%), Gaps = 2/213 (0%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 M +E+CVKAAVG PD LGD PFSQR LLTLEEK + Y++ LI++ +KP WFL ISP+GKV Sbjct: 18 MGVEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKV 77 Query: 61 PVLKIDD-KWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGS 119 PV D KW+ DSDVI ++EEKYP P L TP E+ASVGS IF F TFLKSKD NDGS Sbjct: 78 PVFNGGDGKWIPDSDVITQVIEEKYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDPNDGS 137 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E ALL EL+ALE HLK+H GPFI G+ +SA DLSLAPKLYHLQVAL HFK W +PE + Sbjct: 138 EKALLTELQALEEHLKAH-GPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTN 196 Query: 180 VHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 VH Y + LFS +SF KTK ++++I+GWAPKVN Sbjct: 197 VHAYTEALFSRESFIKTKAAKEHLIAGWAPKVN 229 >2R5G-A nrPDB Length = 247 Score = 89.0 bits (219), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 62/229 (27%), Positives = 113/229 (49%), Gaps = 25/229 (10%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 +E+ VKA + +G+CPF QR + L K + + + ++++ KP+ D++P P Sbjct: 14 IELFVKAGSDG-ESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPF 72 Query: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKS--KDS 115 L + + TD I LE+ +YP K F VG N+F F ++K+ K++ Sbjct: 73 LVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESF-DVGCNLFAKFSAYIKNTQKEA 131 Query: 116 NDGSEHALLVELEALENHLK----------SHDGP------FIAGERVSAVDLSLAPKLY 159 N E +LL E + L+++L S + P F+ G++++ D SL PKL Sbjct: 132 NKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLN 191 Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWA 208 ++VA ++ + +P F V Y+ ++ + F T E+K + + +A Sbjct: 192 IIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYA 240 >5Y7I-A nrPDB Length = 261 Score = 87.4 bits (215), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 59/215 (27%), Positives = 105/215 (48%), Gaps = 21/215 (9%) Query: 2 ALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVP 61 ++E+ +KA +++G+CPF QR + L K + + + +++ KP D++P P Sbjct: 29 SIELFIKAGHDG-ENVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAPGTNPP 87 Query: 62 VLKIDDKWVTDSDVIVGILEEKYPDP--PLKTPA--EFASVGSNIFGTFGTFLKSKDSND 117 L + TD I LE+ P P +P E VG++IF F F+K+ +N Sbjct: 88 FLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNSPNNP 147 Query: 118 GSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLYHL 161 E LL E + L+++L S + F+ G+R++ D +L PKL+ + Sbjct: 148 LQEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVI 207 Query: 162 QVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKT 196 +VA + ++ +P+ F V Y+K D F++T Sbjct: 208 RVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQT 242 >4K0G-A nrPDB Length = 251 Score = 85.5 bits (210), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 58/217 (26%), Positives = 102/217 (47%), Gaps = 25/217 (11%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 +E+ VKA +G+ PFSQR + L K +T+ + ++ + + + P G++P Sbjct: 18 VELFVKAGSDGA-KIGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 76 Query: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDS-- 115 L + TD++ I LE +YP P E + G +IF F ++K+ + Sbjct: 77 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPAL 135 Query: 116 NDGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLY 159 ND E LL L+ L+N+L S F+ G ++ D +L PKL+ Sbjct: 136 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 195 Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKT 196 +QV ++ +++PE+F VH Y+ ++ + F T Sbjct: 196 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAST 232 >2D2Z-A nrPDB Length = 261 Score = 80.1 bits (196), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 58/224 (25%), Positives = 104/224 (46%), Gaps = 25/224 (11%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 +E+ VKA + +G+CPFSQR + L K + + + ++L KP +++P P Sbjct: 19 IELFVKAGSDG-ESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 Query: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSK--DS 115 + + + TD + I LEE KY K P E + G +IF F ++K+ ++ Sbjct: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEA 136 Query: 116 NDGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLY 159 N+ E LL L+ L+ +L S F+ G ++ D +L PKL+ Sbjct: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLH 196 Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYV 203 ++V ++++ +P+ + Y+ +S D F T +K V Sbjct: 197 IVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 >3FY7-A nrPDB Length = 250 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 55/225 (24%), Positives = 100/225 (44%), Gaps = 21/225 (9%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 L++ VKA+ + +G CP QR + L K + + + ++ P D +P ++P+ Sbjct: 26 LQLFVKASEDG-ESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPI 84 Query: 63 LKIDDKWVTDSDVIVGILEEKY--PDPPLKTP--AEFASVGSNIFGTFGTFLKS--KDSN 116 L D TD+ I LEE PD P P E + G+++F F F+K+ + Sbjct: 85 LLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQD 144 Query: 117 DGSEHALLVELEALENHLKS---HD-----------GPFIAGERVSAVDLSLAPKLYHLQ 162 + LL L L+++L++ H+ F+ G+R++ D SL PKL+ + Sbjct: 145 EALYQQLLRALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVD 204 Query: 163 VALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW 207 HF+ +P V Y+ + F+ T +++ + Sbjct: 205 TVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >2YV7-A nrPDB Length = 260 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 46/211 (21%), Positives = 96/211 (45%), Gaps = 8/211 (3%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTL----EEKSLTYKIHLINLSDKPQWFLDISPQG 58 +E+ +KA+ G C F Q + L E K+++ K+ +++ P F Sbjct: 23 IELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEAT 82 Query: 59 KVPVLKIDDKWVTDSDVIVGILEEKYPD--PPLKTPAEFASVGSNIFGTFGTFLKSKDSN 116 P+L + + +++ I + + P E A++ N++ L KD Sbjct: 83 HPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIENLYVKLKLMLVKKD-- 140 Query: 117 DGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES 176 + +ALL L + +HL + + F+ G+ + D L P+L H++VA +F + +P Sbjct: 141 EAKNNALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTH 200 Query: 177 FPHVHNYMKTLFSLDSFEKTKTEEKYVISGW 207 + YM ++ LD+F ++ ++ +I+ + Sbjct: 201 LTALWRYMYHMYQLDAFTQSCPADQDIINHY 231 >4PQI-A nrPDB Length = 241 Score = 63.2 bits (152), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 57/203 (28%), Positives = 98/203 (48%), Gaps = 23/203 (11%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINL--SDKPQWFLD-ISPQGKVPVLKIDDKWVTDSDVI 76 CPF+QR +T K L +I L+ L ++P W+ + + P KVP L+ + K +S + Sbjct: 41 CPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLDL 100 Query: 77 VGILEEKYPDPPL--KTPA--EFA----SVGSNIFGTFGTFLK---SKDSNDGSEHALLV 125 + LE + P L K PA EFA S GT T K +K++ +H Sbjct: 101 IKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAKEAGPAFDH---- 156 Query: 126 ELEALENHL-KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 LEN L K DGPF G+ S VD++ P + L + L + + + ++ Sbjct: 157 ----LENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWI 212 Query: 185 KTLFSLDSFEKTKTEEKYVISGW 207 + + ++++++TKT+ K ++ + Sbjct: 213 EEVNKIEAYKQTKTDPKELVEFY 235 >3LFL-A nrPDB Length = 240 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 12/155 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-KWVTDSDVIVG 78 CPF++R L L+ K + +++ INL +KP+WF +P G VPVL+ + + +S + Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 79 ILEEKY------PDPPLKTPAE--FASVGSNIFGTFGTFLKSKDSND--GSEHALLVELE 128 L+E Y PD P + + + S + G+F++S++ D G + E Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV 163 LE L + F G +S +D + P L+ Sbjct: 152 KLE-VLTNKKTTFFGGNSISMIDYLIWPWFERLEA 185 >3WD6-A nrPDB Length = 256 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 48/158 (30%), Positives = 74/158 (46%), Gaps = 11/158 (6%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CP++QR +L L K + Y++ I+L DKP+W S KVP ++I +D + +S V V Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAIEIAEDVTIYESLVTVE 97 Query: 79 ILEEKYPDPPL--KTPAEFA------SVGSNIFGTFGTFLKSKDS-NDGSEHALLVELEA 129 L+E YP PL + P + A + I F LK D+ N+ A L+ Sbjct: 98 YLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQSLFIKILKFSDTVNEEHVAAYHKALDF 157 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGH 167 ++ LK+ F+ G D + P L+ A H Sbjct: 158 IQEQLKNRGTVFLDGSEPGYADYMIWPWFERLR-AFAH 194 >4QQ7-A nrPDB Length = 207 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 45/159 (28%), Positives = 77/159 (48%), Gaps = 22/159 (13%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 CPFSQR L L EK + ++I ++L +KP+ ++P G+VP+L D + +S++I Sbjct: 14 CPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINEY 73 Query: 80 LEEKYPDPPLKTPAE----------FASVGSNIFGTFGTF--LKSKDSNDGSEHALLVEL 127 ++E++P P L PA+ + +F T K K + E A L Sbjct: 74 IDERFPHPQL-MPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARL--- 129 Query: 128 EALENHLKSH-----DGPFIAGERVSAVDLSLAPKLYHL 161 A+ + L ++ GE S +D+++AP L+ L Sbjct: 130 -AIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRL 167 >3RBT-A nrPDB Length = 246 Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 15/163 (9%) Query: 16 HLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI----DDKWVT 71 H+ P+ R LL LE K + Y+++ ++ P+WF +P+ K+PVL+I D+++ Sbjct: 31 HVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLF 90 Query: 72 DSDVIVGILEEKYPDPPLKTPAEFASVGSNIF-GTFGTFLKSK----DSN--DGSEHALL 124 +S VI L+EKY L + + + F +K D+N GSE ++ Sbjct: 91 ESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLECFDTNFAFGSEQ-II 149 Query: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAP---KLYHLQVA 164 LE E L + + G R +D + P +LY L+ Sbjct: 150 QTLEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLRCV 192 >3QAG-A nrPDB Length = 239 Score = 57.0 bits (136), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 12/156 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CP+S R L L+ K + +++ INL +KP+W+ P G +PVL+ + + +S + Sbjct: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESVIACE 91 Query: 79 ILEEKYPDPPL-----------KTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 L++ YP L K E S ++ L+S + + AL E Sbjct: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRESTNLKAALRQEF 151 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV 163 LE L+ + F G +S +D L P L V Sbjct: 152 SNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDV 187 >1FW1-A nrPDB Length = 216 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 24/190 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINL-SDKPQWFLD----ISPQGKVPVLKIDDKWVTDSDVIV 77 S R + L K + YK INL D Q F ++P +VP LKID + S I+ Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 78 GILEEKYPDPPL--KTPAEFASV---------GSNIFGTFGTFLKSKDSNDGS--EHALL 124 LEE P P L + P + ASV G + + + ++A+ Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAIT 136 Query: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 ALE L+S G + G+ V+ DL L P++ + + FK P +P + + Sbjct: 137 CGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAE----RFKVDLTP--YPTISSIN 190 Query: 185 KTLFSLDSFE 194 K L L++F+ Sbjct: 191 KRLLVLEAFQ 200 >5J5N-A nrPDB Length = 231 Score = 50.1 bits (118), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 79/188 (42%), Gaps = 15/188 (7%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGK-VPVLKIDDKWVTDSDVIVGI 79 PF R L L EK + Y+ +L +K L ++P K +PVL + K V +S +IV Sbjct: 26 PFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQY 85 Query: 80 LEEKYPD-PPLKTPAEFASVGSNIFGTF----------GTFLKSKDSNDGSEHALLVELE 128 ++E + D PL + S + F + K + + ++ + L+ Sbjct: 86 IDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDSLK 145 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 +E L D P+ GE + VD++L P Y A ++++ P + Y K Sbjct: 146 LMEGEL--GDKPYFGGETIGYVDIALVP-FYSWFYAYETIGNFNIEAECPKMIAYCKRCL 202 Query: 189 SLDSFEKT 196 ++ K Sbjct: 203 QKETVSKA 210 >2CZ2-A nrPDB Length = 223 Score = 50.1 bits (118), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 24/188 (12%) Query: 25 RALLTLEEKSLTYKIHLINL-SDKPQWFLD----ISPQGKVPVLKIDDKWVTDSDVIVGI 79 R + L K + Y+I INL D Q F + ++P +VP LKID + S I+ Sbjct: 26 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 85 Query: 80 LEEKYPDPPL-----------KTPAEFASVGSNIFGTFGTFLKSKDSNDG--SEHALLVE 126 LEE P P L + ++ + G + N ++ + Sbjct: 86 LEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSG 145 Query: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKT 186 ALE L+S G + G+ VS D+ L P++ + + FK P +P + + K Sbjct: 146 FNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE----RFKVDLSP--YPTISHINKE 199 Query: 187 LFSLDSFE 194 L +L+ F+ Sbjct: 200 LLALEVFQ 207 >3UAR-A nrPDB Length = 227 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 19/149 (12%) Query: 28 LTLEEKSLTYKIHLINLSDKPQW----FLDISPQGKVPVLKIDDKWV-TDSDVIVGILEE 82 + L E L +++ ++L K FL ++P+G VP L++DD V T+ VI+ L + Sbjct: 18 IVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLDDGQVLTEDQVILQYLAD 77 Query: 83 KYPDPPLKTPAE----------FASVGSNIFGTFGTFLKSKDSNDGSEHALLV---ELEA 129 P+ L P+ A + + I TFG F + + AL + L+ Sbjct: 78 LKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFWNPESPEASKQIALGLLSRRLDY 137 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKL 158 +E+ L++ GP++ G+R S D L+ L Sbjct: 138 VEDRLEA-GGPWLMGDRYSVADAYLSTVL 165 >4AGS-A nrPDB Length = 471 Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 20/171 (11%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDK-PQWFLDISPQGKVPVLKI---DDKWVTDSDV 75 CPF R + EK ++Y + L ++ PQW+ I+P+ VP L++ D +++ +S + Sbjct: 35 CPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADKRFMFESML 94 Query: 76 IVGILEEK-YPDPPL-------KTPAEF--ASVGSNIFGTFGTFLKSKDSNDGSEHALLV 125 I L+ P L + EF A VG I G +D G + + Sbjct: 95 IAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLL---RDPLSGEKRKAMD 151 Query: 126 ELEALENHLKSHD---GPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSV 173 + A + L + + GP+ + D++L P L L+ AL ++ + V Sbjct: 152 DNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDV 202 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 14/162 (8%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CPF RA L E + I + L +P+W+ I+P+ VP L + V +S +IV Sbjct: 261 CPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQ 320 Query: 79 ILE-------EKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELEA-- 129 ++ P + E N G F L S G + ++ A Sbjct: 321 YIDCVATKGSALVPRGDAEKEYEVGFFVENA-GYFVGGLMSWIIRGGEDAKAELQWAAGE 379 Query: 130 LENHLKSH---DGPFIAGERVSAVDLSLAPKLYHLQVALGHF 168 LE L H +GPF G+R++A D+++ P L + + F Sbjct: 380 LEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEF 421 >1E6B-A nrPDB Length = 221 Score = 46.2 bits (108), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 49/199 (24%), Positives = 85/199 (42%), Gaps = 25/199 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 + R + L K L Y+ +NL Q+ F I+P G VP L D + DS I+ Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMY 79 Query: 80 LEEKYPDPPL------KTPAEFASVGSNIFG-------TFGTFLKSK----DSNDGSEHA 122 L+EKYP+PPL K + ++ + G +++ K + +A Sbjct: 80 LDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAWVNNA 139 Query: 123 LLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHN 182 + ALE L + G G+ + DL LAP+++ A+ F+ P +P + Sbjct: 140 ITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHG---AINRFQINMEP--YPTLAK 194 Query: 183 YMKTLFSLDSFEKTKTEEK 201 ++ L +F+ E++ Sbjct: 195 CYESYNELPAFQNALPEKQ 213 >4J2F-A nrPDB Length = 223 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 47/183 (25%), Positives = 82/183 (44%), Gaps = 20/183 (10%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGI 79 PFS R + L+ K + Y+ +L +K L +P K+PVL K + +S +I+ Sbjct: 14 PFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILEY 73 Query: 80 LEEKYPDPPL--KTPAEFASV----------GSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 L+E +P+ PL P E A G+ I+ F T K ++ ++ L V L Sbjct: 74 LDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRT--KGEELEKAVKNCLEV-L 130 Query: 128 EALENH-LKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES--FPHVHNYM 184 + +E H + D + G+++ VD++ + H + V ES FP +H + Sbjct: 131 KTIEEHAMGVSDDKYFGGDKIGIVDIAFC-GIAHWLGVIEEVAGVKVLESQKFPRLHAWT 189 Query: 185 KTL 187 + Sbjct: 190 ENF 192 >4CHS-A nrPDB Length = 219 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 44/194 (22%), Positives = 80/194 (41%), Gaps = 27/194 (13%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGI 79 PF R + L EK + Y+ +L +K L ++P K+PVL + K +++S + V Sbjct: 14 PFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISESLIAVQY 73 Query: 80 LEEKY--------PDPPLKTPAEFAS---------VGSNIFGTFGTFLKSKDSNDGSEHA 122 +EE + DP + A F + +G I+ + G + + ++ Sbjct: 74 IEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKG------EEKEAAKKE 127 Query: 123 LLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHN 182 + L+ LE L D + G+ + VD++L P Y F S ++ P Sbjct: 128 FIEALKLLEEQL--GDKTYFGGDNIGFVDIALVP-FYTWFKVYETFGSLNIENECPRFVA 184 Query: 183 YMKTLFSLDSFEKT 196 + K +S K+ Sbjct: 185 WAKRCLQKESVAKS 198 >2VO4-A nrPDB Length = 219 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 45/195 (23%), Positives = 82/195 (42%), Gaps = 15/195 (7%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGI 79 PF R + L EK + Y+ +L +K L ++P K+PVL + K + +S + V Sbjct: 14 PFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICESLIAVQY 73 Query: 80 LEEKY--------PDPPLKTPAEFAS--VGSNIFGTFGTFLKSK-DSNDGSEHALLVELE 128 +EE + DP + F + V I+ SK + + ++ + L+ Sbjct: 74 IEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAKKEFIEALK 133 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 LE L D + G+ + VD++L P Y A F + ++ P + K Sbjct: 134 LLEEQL--GDKTYFGGDNLGFVDIALVP-FYTWFKAYETFGTLNIESECPKFIAWAKRCL 190 Query: 189 SLDSFEKTKTEEKYV 203 +S K+ +++ V Sbjct: 191 QKESVAKSLPDQQKV 205 >5ECL-B nrPDB Length = 223 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/196 (23%), Positives = 84/196 (42%), Gaps = 15/196 (7%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGIL 80 F RA + L EK + ++ + S+K L +P K+PVL + K V +S +V + Sbjct: 21 FGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYV 80 Query: 81 EEKYP--------DPPLKTPAEF-ASVGSNIF--GTFGTFLKSKDSNDGSEHALLVELEA 129 +E +P DP + A F A F F + K + + + + ++ Sbjct: 81 DEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKI 140 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 LE+ L D P+ G+ VD+SL Q A F ++S+ P + + K Sbjct: 141 LESEL--GDKPYFGGDSFGYVDISLITFSSWFQ-AYEKFGNFSIESESPKLIAWAKRCME 197 Query: 190 LDSFEKTKTEEKYVIS 205 +S K+ + + +++ Sbjct: 198 KESVSKSLPDSEKIVA 213 >3UBL-A nrPDB Length = 242 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 1/71 (1%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 + + L + EK L Y+ I S + + FL ISP GK+PVL++D K++ +S I+ L+ Sbjct: 14 YVNKVKLGILEKGLEYEQIRIAPSQE-EDFLKISPMGKIPVLEMDGKFIFESGAILEFLD 72 Query: 82 EKYPDPPLKTP 92 +P P P Sbjct: 73 TIFPQTPKLIP 83 >3NIV-A nrPDB Length = 222 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 43/176 (24%), Positives = 71/176 (40%), Gaps = 28/176 (15%) Query: 25 RALLTLEEKSLTYK---IHLINLSDKPQ--WFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 R + L K + Y+ +HL+N + + I+PQ VP L I+ + ++ S I+ Sbjct: 16 RVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQILSQSMAIIDY 75 Query: 80 LEEKYPDPP-----------LKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE-------- 120 LEE +P+ P LK+ A + + + K+ + +E Sbjct: 76 LEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQFNANEEQVLEWYH 135 Query: 121 HALLVELEALENHLKS--HDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVP 174 H L +A E L + D P G V D+ L P++Y+ HF S P Sbjct: 136 HWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHRF--HFDMASYP 189 >4MPF-A nrPDB Length = 266 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 43/151 (28%), Positives = 66/151 (43%), Gaps = 24/151 (15%) Query: 39 IHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASV 98 + L+ K + FL I+ GK+P LK D +T+S I+ L KY P P++ + Sbjct: 55 VDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQAR 114 Query: 99 GS----------NIFGTFGTFL------------KSKDSNDGSEHALLVELEALENHLKS 136 I GTFG L K+ + + A+ L+ LE+ Sbjct: 115 ARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLG 174 Query: 137 HDGPFIAGERVSAVDLSLAPKLYHLQVALGH 167 D PF+AG++V+ DL +L VALG+ Sbjct: 175 -DRPFLAGQQVTLADLMALEELMQ-PVALGY 203 >4YH2-A nrPDB Length = 222 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 48/190 (25%), Positives = 83/190 (43%), Gaps = 31/190 (16%) Query: 28 LTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVTDSDVIVGILEEK- 83 LTL +LTY+ +++ + Q +L+ +PQ VP L+ D ++ DS I+ L K Sbjct: 20 LTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKY 79 Query: 84 ------YPDPPLKTPA-------EFASVGSNIFGTF--GTFLKSKDSNDGSEHALLVEL- 127 YP PLK E V +N + + + + ++E+ Sbjct: 80 ADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIY 139 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ--VALGHFKSWSVPESFPHVHNYMK 185 + +E LK D +IAG +++ D SL + L+ VAL K +P + ++K Sbjct: 140 DFVETFLKGQD--YIAGNQLTIADFSLVSSVASLEAFVALDTTK-------YPRIGAWIK 190 Query: 186 TLFSLDSFEK 195 L L +E+ Sbjct: 191 KLEQLPYYEE 200 >3PR8-A nrPDB Length = 229 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Query: 28 LTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEE 82 L L EK LT++ PQ L++SP+GKVPVL+ + +++++ VI+ +E+ Sbjct: 19 LALLEKGLTFEEVTFYGGQAPQA-LEVSPRGKVPVLETEHGFLSETSVILDYIEQ 72 >2PMT-A nrPDB Length = 203 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 7/80 (8%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSDKP----QWFLDISPQGKVPVLKIDD-KWVTD 72 G C S + L E L + I I+L K + FL I+P+G+VPVL++D+ +T+ Sbjct: 8 GSCSLSPH--IVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTE 65 Query: 73 SDVIVGILEEKYPDPPLKTP 92 IV L + PD L P Sbjct: 66 GVAIVQYLADLKPDRNLIAP 85 >2YV9-A nrPDB Length = 291 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/129 (17%), Positives = 56/129 (43%), Gaps = 17/129 (13%) Query: 101 NIFGTFGTFLKSKDSNDGSE-----------------HALLVELEALENHLKSHDGPFIA 143 N++ F FL++K D + + + +L ++ L ++ Sbjct: 125 NLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKSRYLL 184 Query: 144 GERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYV 203 G ++ D L P+L+H+++ + +P +F H+ Y+ T + +F ++ ++ + Sbjct: 185 GNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPADQDI 244 Query: 204 ISGWAPKVN 212 I + ++N Sbjct: 245 IHHYKEQMN 253 >3BBY-A nrPDB Length = 215 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 5/72 (6%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSD----KPQWFLDISPQGKVPVLKIDDKWVTDSDV 75 P+ A + L+EK L++ I I+L +P W +VP+L+IDD +++S Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTW-QGYGQTRRVPLLQIDDFELSESSA 75 Query: 76 IVGILEEKYPDP 87 I LE+++ P Sbjct: 76 IAEYLEDRFAPP 87 >4IGJ-A nrPDB Length = 242 Score = 36.6 bits (83), Expect = 0.009, Method: Compositional matrix adjust. Identities = 40/167 (23%), Positives = 71/167 (42%), Gaps = 39/167 (23%) Query: 25 RALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVT----DSDVIV 77 R L L K L Y+ ++L + Q+ +P +VPVL++++ T S I+ Sbjct: 38 RVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMAIL 97 Query: 78 GILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE---HALLVE-------- 126 LEE++P+P L P +++G ++ N G++ +AL++ Sbjct: 98 EWLEERHPEPALLPP--------DLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPG 149 Query: 127 -------------LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYH 160 L ALE ++ G F G+ + D L P+LY+ Sbjct: 150 WDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYN 196 >3VWX-A nrPDB Length = 222 Score = 36.2 bits (82), Expect = 0.011, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 85/197 (43%), Gaps = 27/197 (13%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDSDVI 76 P + LLTL+ +L ++ ++NL K + +L +PQ VP L+ D + DS I Sbjct: 12 SPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDSHAI 71 Query: 77 VGILEEKYPDPPLKTPAEF---ASVGSNIFGTFGTFLKS-----------KDSNDGSEHA 122 + L KY P + A V ++ G + ++ +H Sbjct: 72 MAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIPQHQ 131 Query: 123 LLVELEA---LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 + +E+ LE+ LK++ ++AG+ ++ D S+ + L VA FP Sbjct: 132 IDSIVESYGFLESFLKNNK--YMAGDHLTIADFSIVTSVTSL-VAFAEIDQ----SKFPK 184 Query: 180 VHNYMKTLFSLDSFEKT 196 + ++K+L SL +E+ Sbjct: 185 LSAWLKSLQSLPFYEEA 201 >2GDR-A nrPDB Length = 202 Score = 35.4 bits (80), Expect = 0.016, Method: Compositional matrix adjust. Identities = 35/156 (22%), Positives = 68/156 (43%), Gaps = 24/156 (15%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSDKP----QWFLDISPQGKVPVLKIDD-KWVTD 72 G C S + L E L +++ ++L+ K Q +L+++P G VP L++DD + +T+ Sbjct: 8 GACSLSPH--IALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTE 65 Query: 73 SDVIVGILEEKYPDPPLKTPAE-----------FASVGSNIFGTFGTFLKSKDSN---DG 118 IV + ++ P L PA + S + +F S+ + Sbjct: 66 GPAIVQYVADQVPGKQL-APANGSFERYHLQQWLNFISSELHKSFSPLFNPASSDEWKNA 124 Query: 119 SEHALLVELEALENHLKSHDGPFIAGERVSAVDLSL 154 +L L + L+ P++ G+++S D+ L Sbjct: 125 VRQSLNTRLGQVARQLE--HAPYLLGDQLSVADIYL 158 >5ZWP-A nrPDB Length = 208 Score = 35.4 bits (80), Expect = 0.018, Method: Compositional matrix adjust. Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 23/166 (13%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSD----KPQWFLDISPQGKVPVLKIDDKWVTDS 73 G P + L+T + + L+NL KP+ FL I+PQ +P L D + +S Sbjct: 8 GSAP-CRSVLMTAKALGIELNKKLLNLQAGEHLKPE-FLKINPQHTIPTLVDGDFALWES 65 Query: 74 DVIVGILEEKYPDPPL---KTPAEFASVGSNIFGTFGTFLKSKD--------SNDGSEHA 122 I+ L EKY K P + A + ++ GT KS + ++ Sbjct: 66 RAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPADPE 125 Query: 123 LLVELEA----LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVA 164 L ++E L LK H+ + AG+ ++ DL+L + +VA Sbjct: 126 LFKKIETAFDFLNTFLKGHE--YAAGDSLTVADLALLASVSTFEVA 169 >6EP7-A nrPDB Length = 220 Score = 34.3 bits (77), Expect = 0.037, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGIL 80 + R + LEEK + Y+ +LS+K L ++P K+PVL + K + +S + V + Sbjct: 15 YGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVLIHEGKPICESIIQVQYI 74 Query: 81 EEKYPD 86 +E +PD Sbjct: 75 DELWPD 80 >3R2Q-A nrPDB Length = 202 Score = 33.5 bits (75), Expect = 0.062, Method: Compositional matrix adjust. Identities = 48/196 (24%), Positives = 85/196 (43%), Gaps = 26/196 (13%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDK--WVTDSDVIVG 78 PF ++ + L EK +T++ + +P GKVPVL ++ W DS +I Sbjct: 10 PFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWF-DSPIIAE 68 Query: 79 ILE------EKYPDPPLKT----PAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELE 128 +E P PL++ E + G G +++ + SE LL + E Sbjct: 69 YIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQRE 128 Query: 129 ALENHLKSHDGPFIAG----ERVSAVDLSLAPKLYHL---QVALGHFKSWSVPESFPHVH 181 + L +G + G + V+ +++A + +L +VA G W V PH+ Sbjct: 129 KINRSLDVLEGYLVDGTLKTDTVNLATIAIACAVGYLNFRRVAPG----WCVDR--PHLV 182 Query: 182 NYMKTLFSLDSFEKTK 197 ++ LFS +SF +T+ Sbjct: 183 KLVENLFSRESFARTE 198 >5F06-A nrPDB Length = 216 Score = 33.1 bits (74), Expect = 0.094, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%) Query: 12 GAPDHLGDCPFSQRALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQGKVPVLKIDDK 68 GAP + C + R L L EK+L +++ ++L K FL +P G++P L+ DD Sbjct: 6 GAP--MSTC--TSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 69 WVTDSDVIVGILEEKY 84 + +S I + EK+ Sbjct: 62 TLFESRAITSYIAEKF 77 >4EAH-A nrPDB Length = 402 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 32/59 (54%) Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 AL N++ S + G ++ ++DL L K ++ L HF + +V E +P + N+ + L Sbjct: 220 ALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQEL 278 >4RI7-A nrPDB Length = 215 Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust. Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSD----KPQWFLDISPQGKVPVLKIDDKWVTDSDV 75 C R L TL EK + + + I+LS KP+ +L I P G+VP K + + +S Sbjct: 13 CTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPE-YLKIQPFGQVPAFKDESITLFESRA 71 Query: 76 IVGILEEKYPD 86 I + +KY D Sbjct: 72 ICRYICDKYAD 82 >5NR1-A nrPDB Length = 228 Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust. Identities = 44/168 (26%), Positives = 70/168 (41%), Gaps = 35/168 (20%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKW-----VTDSDV 75 P S++ L L EK L + + + P F ++P G PVL ++ K + ++ Sbjct: 14 PASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVL-VETKHQRNLVICETRA 72 Query: 76 IVGILEEKYPDPPL--KTPAEFASVGSNIFGTF---------GTFLKSKDS--------- 115 I+ +EE +PPL + PAE A + F G L K Sbjct: 73 ILEHIEETETEPPLLGRDPAERAE-ARRLLQWFDRKFDNEVNGFLLHEKMEKRLLRMGAP 131 Query: 116 -----NDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKL 158 G E AL + L +E+ L++ D ++AG R+S D + A L Sbjct: 132 DLAALRQGRE-ALRMHLGYIESLLQTRD--WLAGRRMSLADFAAAAHL 176 >4OXR-A nrPDB Length = 285 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 3/114 (2%) Query: 13 APDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTD 72 + D D P +R ++T E + Y ++ W ++ QG +K +V + Sbjct: 164 SKDKFNDIPKEKRVMIT-SEGAFKYFAQQFDVKPGYIWEINTENQGTPEQMKQAVDFVKE 222 Query: 73 SDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVE 126 + + +LE D +K+ E G+ I+GT T K +DG + ++E Sbjct: 223 NHIKNLLLETSVSDKSMKSLGE--ETGAKIYGTVYTDSIGKKGSDGDSYYKMME 274 >6F05-A nrPDB Length = 215 Score = 31.6 bits (70), Expect = 0.23, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 28/159 (17%) Query: 24 QRALLTLEEKSLTYK---IHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGIL 80 +RAL+TL EK + ++ + L+ K +L + P G VP + D + +S ++ + Sbjct: 14 KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYV 73 Query: 81 EEKY----PDPPLKTPAEFASVGS-------------------NIFGTFGTFLKSKDSND 117 EKY PD KT + V +F + F + Sbjct: 74 AEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIK 133 Query: 118 GSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAP 156 SE L L+ E HL ++AG+ VS DL+ P Sbjct: 134 ESEEKLAGVLDVYEAHLSK--SKYLAGDFVSLADLAHLP 170 >1JLV-A nrPDB Length = 209 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 18/123 (14%) Query: 47 KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKY-PDPPL--KTPAEFASVGSNIF 103 KP+ FL I+PQ +P L + + +S I L EKY D L K P + A V ++ Sbjct: 40 KPE-FLKINPQHCIPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLY 98 Query: 104 GTFGTFLKS------------KDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVD 151 GT + + +N +E + ++ L L H ++AG+ ++ D Sbjct: 99 FDMGTLYQRFADYYYPQIFAKQPANAENEKKMKDAVDFLNTFLDGHK--YVAGDSLTIAD 156 Query: 152 LSL 154 L++ Sbjct: 157 LTV 159 >2JL4-A nrPDB Length = 213 Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 23 SQRALLTLEEKSLTYK---IHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 S R + L K + Y+ +HL F ++PQ VP L + + S I+ Sbjct: 13 SHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQVLIQSPAIIEW 72 Query: 80 LEEKYPDPPL 89 LEE+YP P L Sbjct: 73 LEEQYPTPAL 82 >4PXO-A nrPDB Length = 238 Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust. Identities = 49/198 (24%), Positives = 76/198 (38%), Gaps = 35/198 (17%) Query: 25 RALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVL-KIDDKWVTDSDVIVGIL 80 R + L K + Y+ ++L Q FL I+PQG VP L D +T S I+ L Sbjct: 37 RVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALFDGDGPPLTQSLAILDYL 96 Query: 81 EEKYPDPPL---------------------KTPAEFASVGSNIFGTFGTFLKSKDSNDGS 119 EE PL P V + + +G L + + Sbjct: 97 EETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMENYG--LPRERMLEFL 154 Query: 120 EHALLVELEALENHL--KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESF 177 +A + L+ LE L ++ G F G+ VS DL L L V G F + ++ Sbjct: 155 RNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLC----LISLWVGTGIFGIDTA--AY 208 Query: 178 PHVHNYMKTLFSLDSFEK 195 P V + + +LD+ + Sbjct: 209 PTVKRISEEVLALDAVAR 226 >5EY6-A nrPDB Length = 217 Score = 31.2 bits (69), Expect = 0.30, Method: Compositional matrix adjust. Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 10/83 (12%) Query: 25 RALLTLEEKSLTYKIHLINLSD----KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGIL 80 R L+TL EK + ++I +++S KP +L I P G+VP + + + +S I + Sbjct: 17 RVLVTLLEKDVPFQIIPVDMSKGEHKKPD-YLKIQPFGQVPAFQDESISLFESRSICRYV 75 Query: 81 EEKYPDPPLK-----TPAEFASV 98 EKY D K P E AS+ Sbjct: 76 CEKYADRGDKGLYGTNPLERASI 98 >3QMX-A nrPDB Length = 99 Score = 30.8 bits (68), Expect = 0.39, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGK--VPVLKIDDKWVTDSDVIV 77 CPF RAL L+ K + ++ + I+ ++ + + GK +P + IDD+ + D I Sbjct: 26 CPFCMRALALLKRKGVEFQEYCIDGDNEAREAMAARANGKRSLPQIFIDDQHIGGCDDIY 85 Query: 78 GILEEKYPDPPLKT 91 + DP L + Sbjct: 86 ALDGAGKLDPLLHS 99 >4PNG-A nrPDB Length = 229 Score = 30.8 bits (68), Expect = 0.45, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 28 LTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKY 84 LTL + Y+ +N K + FL +PQ VP L+ D ++ DS I+ L KY Sbjct: 26 LTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKY 85 >3TOT-A nrPDB Length = 226 Score = 30.4 bits (67), Expect = 0.57, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 26/47 (55%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD 67 P++++ + L EK + Y+ L ++ + +P GKVP L +DD Sbjct: 12 PYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDD 58 >3M8N-A nrPDB Length = 225 Score = 30.0 bits (66), Expect = 0.76, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 20/122 (16%) Query: 51 FLDISPQGKVPVLKID-DKWVTDSDVIVGILE---EKYPDPPLKTPA-------EFASVG 99 FL +P G+VP+L+ +++ +S+ I+ L PD + E ++ Sbjct: 46 FLAKNPSGQVPLLETAPGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALE 105 Query: 100 SNIFGTFGTFLKSKDSNDGSEHAL-------LVELEALENHLKSHDGPFIAGERVSAVDL 152 NI + K D HAL L+ +ENHLK++D + A +++ D+ Sbjct: 106 PNIGSAYFWLCLVKGGRDLQTHALEDWLERGYAALQVMENHLKTND--YFAAGQLTIADI 163 Query: 153 SL 154 +L Sbjct: 164 AL 165 >4B7G-A nrPDB Length = 515 Score = 30.0 bits (66), Expect = 0.82, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLY---HLQVALGHFKSWSVPESFPHV 180 L + H+G + E +SA P + HL L HF +VPE PH Sbjct: 18 LSGNTTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHA 71 >5F07-A nrPDB Length = 213 Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust. Identities = 46/177 (25%), Positives = 69/177 (38%), Gaps = 32/177 (18%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQ---WFLDISPQGKVPVLKIDDKWVTDSDVI 76 CP QR + L EK + + + ++L Q FL P G+VPV++ D + +S I Sbjct: 12 CP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAI 69 Query: 77 VGILEEKYPD--PPL--KTPAEFASVGS--------------NIFGTFGTFLKSKDSNDG 118 + KY D P L T E A V NI F + + G Sbjct: 70 IRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNI--VFQVVILPRIGQQG 127 Query: 119 SEHALLVELEALENHLKSHD-----GPFIAGERVSAVDLSLAPKLYHL--QVALGHF 168 + E LE L ++ ++AG+ + DLS P +L + LGH Sbjct: 128 DSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLPATRYLVNEAGLGHL 184 >1AW9-A nrPDB Length = 216 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 13 APDHLGDCPFSQ---RALLTLEEKSLTYKIHLINLSD---KPQWFLDISPQGKVPVLKID 66 AP L P S R L EK L ++I ++L+ K FL ++P G++P L Sbjct: 1 APLKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDG 60 Query: 67 DKWVTDSDVIVGILEEKY 84 D+ + +S I + KY Sbjct: 61 DEVLFESRAINRYIASKY 78 >1PN9-A nrPDB Length = 209 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 18/133 (13%) Query: 47 KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKY-PDPPL--KTPAEFASVGSNIF 103 KP+ FL ++PQ +P L + + +S I L EKY D L K P + A V ++ Sbjct: 40 KPE-FLKLNPQHCIPTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLY 98 Query: 104 GTFGTFLKS------------KDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVD 151 GT + + +N +E + + L L+ + + AG ++ D Sbjct: 99 FDMGTLYQRFADYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQE--YAAGNDLTIAD 156 Query: 152 LSLAPKLYHLQVA 164 LSLA + +VA Sbjct: 157 LSLAATIATYEVA 169 >2VCV-A nrPDB Length = 222 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 A E L+SH ++ G ++S D+SL LY+++ Sbjct: 135 AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVE 168 >3QH2-A nrPDB Length = 221 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Query: 150 VDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL-DSFEKTKTEEKYVISG 206 VD++L ++ +Q+ G F + FPH+H +++ SL ++ + K + YV+ G Sbjct: 81 VDIALFSTIHRVQLPSGSFSPKQIRARFPHLH-IGRSVHSLEEAVQAEKEDADYVLFG 137 >3GH6-A nrPDB Length = 210 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 20/153 (13%) Query: 38 KIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKY-PDPPL--KT 91 K +IN + Q+ +L I+PQ +P L + +S I+ L EKY D L K Sbjct: 28 KKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWESRAIMVYLVEKYGKDDKLFPKD 87 Query: 92 PAEFASVGSNIFGTFGTFLKS------------KDSNDGSEHALLVELEALENHLKSHDG 139 + A + ++ GT KS K +N+ + + V E L L+ Sbjct: 88 VQKQALINQRLYFDMGTLYKSFSEYYYPQIFLKKPANEENYKKIEVAFEFLNTFLEGQ-- 145 Query: 140 PFIAGERVSAVDLSLAPKLYHLQVALGHFKSWS 172 + AG S D++ + VA FK ++ Sbjct: 146 TYSAGGDYSLADIAFLATVSTFDVAGFDFKRYA 178 >3MAK-A nrPDB Length = 209 Score = 28.5 bits (62), Expect = 2.1, Method: Compositional matrix adjust. Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 23/166 (13%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSD----KPQWFLDISPQGKVPVLKIDDKWVTDS 73 G P + ++T + + L+NL KP+ FL I+PQ +P L + + +S Sbjct: 9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPE-FLKINPQHTIPTLVDNGFALWES 66 Query: 74 DVIVGILEEKYPDPPL---KTPAEFASVGSNIFGTFGTFLKS------------KDSNDG 118 I L EKY K P + A + ++ GT +S ++ Sbjct: 67 RAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPE 126 Query: 119 SEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVA 164 + + E L L+ D + AG+ ++ D++L + +VA Sbjct: 127 AFKKIEAAFEFLNTFLEGQD--YAAGDSLTVADIALVATVSTFEVA 170 >3IBH-A nrPDB Length = 233 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 7/53 (13%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLS------DKPQWFLDISPQGKVPVLKIDD 67 P+ R + L EK++ + + ++ KP+ FL + G VPVL++DD Sbjct: 28 PYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPE-FLAKNYSGTVPVLELDD 79 >2VCT-A nrPDB Length = 222 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 A E LKSH ++ G ++S D+ L LY+++ Sbjct: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >3I6A-A nrPDB Length = 222 Score = 28.1 bits (61), Expect = 2.9, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 A E LKSH ++ G ++S D+ L LY+++ Sbjct: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >1PL2-A nrPDB Length = 222 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 A E LKSH ++ G ++S D+ L LY+++ Sbjct: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >1F2E-A nrPDB Length = 201 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 17/100 (17%) Query: 51 FLDISPQGKVPVLKIDD-KWVTDSDVIVGILEEKYPDPPLKTPAE-----------FASV 98 FL ++P GKVP L +D + +T++ I+ + ++ P L PAE + + Sbjct: 43 FLTVNPSGKVPALTLDSGETLTENPAILLYIADQNPASGL-APAEGSLDRYRLLSRLSFL 101 Query: 99 GSNIFGTFGTFLKSKDSNDGSEHALLVELEALENHLKSHD 138 GS F S++ A E+++NHL + D Sbjct: 102 GSEFHKAFVPLFAPATSDEAKAAA----AESVKNHLAALD 137 >4USS-A nrPDB Length = 325 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 4/77 (5%) Query: 141 FIAGERVSAVDLSLAPKLYHL-QVALGHFK-SWSVPESFPHVHNYMKTLFSLDSFEKTKT 198 +I G +S D+ L L +V HFK + + +P++ NY K +F + T Sbjct: 226 YICGNTLSEADIKLFVTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMSSTVN 285 Query: 199 EE--KYVISGWAPKVNP 213 + K G P VNP Sbjct: 286 MQHIKRHYYGSHPTVNP 302 >4IKH-A nrPDB Length = 244 Score = 27.7 bits (60), Expect = 4.0, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 23/47 (48%), Gaps = 3/47 (6%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVL 63 P + + LEE L Y+ H ++ + Q FL +SP K+P + Sbjct: 30 TPNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAI 76 >4M2B-A nrPDB Length = 505 Score = 27.3 bits (59), Expect = 4.7, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 23/44 (52%) Query: 123 LLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALG 166 L V LE ++ H + P I E+ S +PK+Y L+ A+G Sbjct: 314 LPVLLETMQEHGGTLPLPVIRNEKTVDSSNSASPKVYQLETAMG 357 >6BYC-A nrPDB Length = 862 Score = 27.3 bits (59), Expect = 4.8, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 8/73 (10%) Query: 8 KAAVGA--PDHLGDCPFSQRALLTLEEKSLTYKIHLI----NLSDKPQWFLDISPQGKVP 61 KA+V A H+G+ FS + LL + TY + + L + F + Q +P Sbjct: 719 KASVNALSSQHVGN--FSDKQLLGSADPKRTYAVFELLDGDTLLSREVVFFAPAKQLALP 776 Query: 62 VLKIDDKWVTDSD 74 KID +W D D Sbjct: 777 AAKIDSQWRADGD 789 >1F3B-A nrPDB Length = 222 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 L A E LKSH ++ G R++ VD+ L L +++ Sbjct: 132 LPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVE 167 >5F05-A nrPDB Length = 212 Score = 26.6 bits (57), Expect = 8.4, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 23 SQRALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 +QR L TL EK + +++ +NL K + + ++P G+VP D + +S I Sbjct: 14 TQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQY 73 Query: 80 LEEKY 84 + +Y Sbjct: 74 VAHQY 78 >2C3Q-A nrPDB Length = 247 Score = 26.6 bits (57), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 20/37 (54%) Query: 51 FLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYPDP 87 F ++P KVP LK D +T+S I+ L KY P Sbjct: 52 FAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKVP 88 >2IL3-A nrPDB Length = 221 Score = 26.6 bits (57), Expect = 9.1, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 7/78 (8%) Query: 28 LTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKY-PD 86 L LE+K+ I+L+ F+ ++PQ +PVL + +T+S I+ L KY D Sbjct: 27 LELEQKT----INLLTGDHLKPEFVKLNPQHTIPVLDDNGTIITESHAIMIYLVTKYGKD 82 Query: 87 PPL--KTPAEFASVGSNI 102 L K P + A V S + Sbjct: 83 DSLYPKDPVKQARVNSAL 100 >5F0G-A nrPDB Length = 215 Score = 26.2 bits (56), Expect = 10.0, Method: Compositional matrix adjust. Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 18/141 (12%) Query: 47 KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKY-PDPPL--KTPAEFASVGSNIF 103 KP+ F+ ++PQ +P L + + +S I L EKY D L P + A + ++ Sbjct: 40 KPE-FVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLY 98 Query: 104 GTFGT------------FLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVD 151 GT F K +D + L+ L+ + ++AG++++ D Sbjct: 99 FDMGTLYESFAKYYYPLFRTGKPGSDEDLKRIETAFGFLDTFLEGQE--YVAGDQLTVAD 156 Query: 152 LSLAPKLYHLQVALGHFKSWS 172 +++ + +V+ F +S Sbjct: 157 IAILSTVSTFEVSEFDFSKYS 177 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5ELG-A nrPDB 295 8e-81 5IQY-A nrPDB 272 9e-74 5D9W-A nrPDB 269 7e-73 5LOL-A nrPDB 269 7e-73 5N9U-A nrPDB 264 1e-71 5Y7I-A nrPDB 226 7e-60 2R5G-A nrPDB 217 4e-57 2D2Z-A nrPDB 212 9e-56 4K0G-A nrPDB 209 9e-55 2YV7-A nrPDB 200 4e-52 3FY7-A nrPDB 196 5e-51 5J5N-A nrPDB 179 9e-46 2VO4-A nrPDB 178 1e-45 4CHS-A nrPDB 174 2e-44 5ECL-B nrPDB 170 4e-43 3QAG-A nrPDB 152 8e-38 4J2F-A nrPDB 150 3e-37 2CZ2-A nrPDB 150 4e-37 1FW1-A nrPDB 148 1e-36 3LFL-A nrPDB 147 4e-36 1E6B-A nrPDB 146 7e-36 4PQI-A nrPDB 145 9e-36 3WD6-A nrPDB 145 1e-35 3RBT-A nrPDB 141 3e-34 4QQ7-A nrPDB 140 3e-34 4AGS-A nrPDB 135 9e-33 3NIV-A nrPDB 125 1e-29 3UAR-A nrPDB 110 4e-25 4MPF-A nrPDB 109 9e-25 4YH2-A nrPDB 108 1e-24 3UBL-A nrPDB 88 3e-18 Sequences not found previously or not previously below threshold: 5G5A-A nrPDB 161 2e-40 6EP7-A nrPDB 149 6e-37 1OYJ-A nrPDB 120 4e-28 2YV9-A nrPDB 110 5e-25 4IGJ-A nrPDB 107 4e-24 1GWC-A nrPDB 102 1e-22 2JL4-A nrPDB 99 1e-21 4PNG-A nrPDB 98 2e-21 4PXO-A nrPDB 97 6e-21 3TOT-A nrPDB 95 2e-20 3VWX-A nrPDB 95 2e-20 1AW9-A nrPDB 93 8e-20 3LG6-A nrPDB 92 1e-19 6JWK-A nrPDB 85 2e-17 5F06-A nrPDB 83 6e-17 1JLV-A nrPDB 83 6e-17 3IBH-A nrPDB 83 6e-17 4MK3-A nrPDB 83 8e-17 1PN9-A nrPDB 83 9e-17 5ZWP-A nrPDB 82 1e-16 2IL3-A nrPDB 80 5e-16 5EY6-A nrPDB 80 1e-15 1F2E-A nrPDB 78 2e-15 3MAK-A nrPDB 78 2e-15 2PMT-A nrPDB 78 2e-15 2GDR-A nrPDB 78 3e-15 5F07-A nrPDB 77 4e-15 5A5K-A nrPDB 77 5e-15 3GH6-A nrPDB 77 8e-15 1V2A-A nrPDB 76 1e-14 5F0G-A nrPDB 74 4e-14 6F05-A nrPDB 74 5e-14 1N2A-A nrPDB 73 1e-13 3M3M-A nrPDB 73 1e-13 5NR1-A nrPDB 73 1e-13 2C3Q-A nrPDB 72 1e-13 3PR8-A nrPDB 72 2e-13 4RI7-A nrPDB 72 2e-13 1AXD-A nrPDB 72 2e-13 3R2Q-A nrPDB 70 9e-13 5F05-A nrPDB 70 1e-12 3M8N-A nrPDB 69 1e-12 3GX0-A nrPDB 69 2e-12 3C8E-A nrPDB 65 2e-11 4FQU-A nrPDB 65 2e-11 1U3I-A nrPDB 64 4e-11 3LSZ-A nrPDB 64 5e-11 4IKH-A nrPDB 63 6e-11 1YQ1-A nrPDB 63 1e-10 3M1G-A nrPDB 62 1e-10 2CA8-A nrPDB 62 2e-10 2GLR-A nrPDB 60 6e-10 6GZF-A nrPDB 60 9e-10 4Q5F-A nrPDB 59 1e-09 1G6W-A nrPDB 58 3e-09 4MDC-A nrPDB 57 4e-09 1VF1-A nrPDB 56 1e-08 2PVQ-A nrPDB 55 2e-08 3BBY-A nrPDB 55 3e-08 18GS-A nrPDB 54 4e-08 1F3B-A nrPDB 54 4e-08 3PPU-A nrPDB 53 8e-08 4PTS-A nrPDB 53 8e-08 1B48-A nrPDB 52 1e-07 2VCV-A nrPDB 52 1e-07 1GUL-A nrPDB 52 2e-07 6GCB-A nrPDB 52 3e-07 5AN1-A nrPDB 51 5e-07 2VCT-A nrPDB 50 9e-07 3KXO-A nrPDB 49 1e-06 4LMW-A nrPDB 49 2e-06 3I6A-A nrPDB 49 2e-06 6GC9-A nrPDB 49 2e-06 2FHE-A nrPDB 48 2e-06 1ZL9-A nrPDB 48 3e-06 1PL2-A nrPDB 48 3e-06 1EV4-A nrPDB 47 4e-06 2AAW-A nrPDB 47 5e-06 4G0L-A nrPDB 47 5e-06 5Y9Z-A nrPDB 47 5e-06 2HNL-A nrPDB 47 8e-06 5LCZ-A nrPDB 46 1e-05 1G7O-A nrPDB 46 1e-05 4USS-A nrPDB 46 2e-05 5F8B-A nrPDB 45 3e-05 5FWG-A nrPDB 43 1e-04 1TU7-A nrPDB 43 1e-04 1B4P-A nrPDB 42 2e-04 1GSQ-A nrPDB 42 2e-04 3IR4-A nrPDB 42 2e-04 2PBJ-A nrPDB 41 3e-04 4Q5R-A nrPDB 41 3e-04 2DC5-A nrPDB 41 4e-04 1HNA-A nrPDB 41 4e-04 1FHE-A nrPDB 41 5e-04 5LKB-A nrPDB 39 0.001 1XWK-A nrPDB 39 0.002 4LMV-A nrPDB 38 0.002 4LA1-A nrPDB 38 0.002 4GTU-A nrPDB 38 0.003 1M0U-A nrPDB 37 0.005 4BVY-B nrPDB 37 0.005 2WRT-A nrPDB 36 0.013 3GRX-A nrPDB 35 0.024 2KLX-A nrPDB 35 0.036 1NM3-A nrPDB 33 0.074 3GTU-B nrPDB 33 0.074 3QMX-A nrPDB 33 0.090 1GSU-A nrPDB 32 0.24 1Z7R-A nrPDB 31 0.32 5W1J-A nrPDB 30 0.68 3UIW-A nrPDB 30 0.87 5CAX-A nrPDB 30 1.2 4ES6-A nrPDB 29 1.3 3IC4-A nrPDB 29 1.3 3C1S-A nrPDB 29 1.7 2MZC-A nrPDB 28 2.1 6JR6-A nrPDB 28 2.3 1H75-A nrPDB 28 2.7 3OPB-A nrPDB 28 4.4 5DXT-A nrPDB 28 4.6 2WYO-A nrPDB 27 6.9 3PJP-A nrPDB 26 8.5 >5ELG-A nrPDB Length = 221 Score = 295 bits (756), Expect = 8e-81, Method: Composition-based stats. Identities = 213/213 (100%), Positives = 213/213 (100%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV Sbjct: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 Query: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE Sbjct: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 Query: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV Sbjct: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 Query: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP 213 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP Sbjct: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP 213 >5IQY-A nrPDB Length = 216 Score = 272 bits (695), Expect = 9e-74, Method: Composition-based stats. Identities = 141/213 (66%), Positives = 171/213 (80%), Gaps = 2/213 (0%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MA+E+CVKAAVGAPD LGDCPFSQR LLTLEEK +TY++ L++LS+KP+WFL ISP+GKV Sbjct: 4 MAVEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKV 63 Query: 61 PVLKI-DDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGS 119 PV D KW+ DSDVI ++EEK+P P L TP E+ASVGS IF +F FLKSKD++DGS Sbjct: 64 PVFNSGDGKWIADSDVITQVIEEKFPTPSLVTPPEYASVGSKIFPSFVKFLKSKDASDGS 123 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E ALL EL+AL+ HLK+H GP+I+GE VSA DLSL PKL+HLQVAL HFK W +PE+ Sbjct: 124 EKALLDELQALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTS 182 Query: 180 VHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 VH Y K LFS +SF KTK +Y+I+GWAPKVN Sbjct: 183 VHAYTKALFSRESFVKTKPANQYLIAGWAPKVN 215 >5D9W-A nrPDB Length = 230 Score = 269 bits (688), Expect = 7e-73, Method: Composition-based stats. Identities = 139/213 (65%), Positives = 165/213 (77%), Gaps = 2/213 (0%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 M +E+CVKAAVG PD LGD PFSQR LLTLEEK + Y++ LI++ +KP WFL ISP+GKV Sbjct: 18 MGVEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKV 77 Query: 61 PVLKI-DDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGS 119 PV D KW+ DSDVI ++EEKYP P L TP E+ASVGS IF F TFLKSKD NDGS Sbjct: 78 PVFNGGDGKWIPDSDVITQVIEEKYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDPNDGS 137 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E ALL EL+ALE HLK+H GPFI G+ +SA DLSLAPKLYHLQVAL HFK W +PE + Sbjct: 138 EKALLTELQALEEHLKAH-GPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTN 196 Query: 180 VHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 VH Y + LFS +SF KTK ++++I+GWAPKVN Sbjct: 197 VHAYTEALFSRESFIKTKAAKEHLIAGWAPKVN 229 >5LOL-A nrPDB Length = 215 Score = 269 bits (687), Expect = 7e-73, Method: Composition-based stats. Identities = 161/212 (75%), Positives = 184/212 (86%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MAL+ICVK AVGAPD LGDCPFSQR LLTLEEK L YK HLIN+SDKPQWFLDISP+GKV Sbjct: 3 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 62 Query: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 PV+K+D KWV DSDVIVG+LEEKYP+P LKTP EFASVGS IFG F TFLKSKD+NDGSE Sbjct: 63 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 122 Query: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 AL+ ELEALENHLK+H GPF+AGE+++AVDLSLAPKLYHL+VALGH+K+WSVPES V Sbjct: 123 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 182 Query: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 NY K LFS +SFE TK +++ V++GW KVN Sbjct: 183 RNYAKALFSRESFENTKAKKEIVVAGWESKVN 214 >5N9U-A nrPDB Length = 218 Score = 264 bits (676), Expect = 1e-71, Method: Composition-based stats. Identities = 156/212 (73%), Positives = 182/212 (85%), Gaps = 1/212 (0%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 MALEICVKAAVGAP+ LGDCPF QR LL+LEEK + YK HLINL DKPQWFL+ISP+GKV Sbjct: 1 MALEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKV 60 Query: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 PV+KIDDKWV DSDVIVGILEEK P+PPL TP EFASVGS IF +F FLKSKD NDG+E Sbjct: 61 PVVKIDDKWVADSDVIVGILEEKNPEPPLATPPEFASVGSKIFPSFVKFLKSKDPNDGTE 120 Query: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 ALL EL+AL+ HLK H GPFIAGE+++AVDLSLAPKLYHL+VALGHFK+W +P++ HV Sbjct: 121 QALLEELKALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHV 179 Query: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 NY+K LFS +SF+KT+ E++VI+GW PKVN Sbjct: 180 LNYIKLLFSRESFKKTRAAEEHVIAGWEPKVN 211 >5Y7I-A nrPDB Length = 261 Score = 226 bits (576), Expect = 7e-60, Method: Composition-based stats. Identities = 60/231 (25%), Positives = 109/231 (47%), Gaps = 21/231 (9%) Query: 2 ALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVP 61 ++E+ +KA +++G+CPF QR + L K + + + +++ KP D++P P Sbjct: 29 SIELFIKAGHDG-ENVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAPGTNPP 87 Query: 62 VLKIDDKWVTDSDVIVGILEEKY--PDPPLKTPA--EFASVGSNIFGTFGTFLKSKDSND 117 L + TD I LE+ P P +P E VG++IF F F+K+ +N Sbjct: 88 FLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNSPNNP 147 Query: 118 GSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLYHL 161 E LL E + L+++L S + F+ G+R++ D +L PKL+ + Sbjct: 148 LQEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVI 207 Query: 162 QVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 +VA + ++ +P+ F V Y+K D F++T + + + N Sbjct: 208 RVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVAN 258 >2R5G-A nrPDB Length = 247 Score = 217 bits (552), Expect = 4e-57, Method: Composition-based stats. Identities = 60/228 (26%), Positives = 111/228 (48%), Gaps = 23/228 (10%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 +E+ VKA + +G+CPF QR + L K + + + ++++ KP+ D++P P Sbjct: 14 IELFVKAGSDG-ESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPF 72 Query: 63 LKIDDKWVTDSDVIVGILEEKY--PDPPLKTP--AEFASVGSNIFGTFGTFLKS--KDSN 116 L + + TD I LE+ P P +P E VG N+F F ++K+ K++N Sbjct: 73 LVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEAN 132 Query: 117 DGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLYH 160 E +LL E + L+++L + F+ G++++ D SL PKL Sbjct: 133 KNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNI 192 Query: 161 LQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWA 208 ++VA ++ + +P F V Y+ ++ + F T E+K + + +A Sbjct: 193 IKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYA 240 >2D2Z-A nrPDB Length = 261 Score = 212 bits (540), Expect = 9e-56, Method: Composition-based stats. Identities = 58/229 (25%), Positives = 106/229 (46%), Gaps = 25/229 (10%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 +E+ VKA + +G+CPFSQR + L K + + + ++L KP +++P P Sbjct: 19 IELFVKAGSDG-ESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 Query: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSK--DS 115 + + + TD + I LEE KY K P E + G +IF F ++K+ ++ Sbjct: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEA 136 Query: 116 NDGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLY 159 N+ E LL L+ L+ +L S F+ G ++ D +L PKL+ Sbjct: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLH 196 Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWA 208 ++V ++++ +P+ + Y+ +S D F T +K V ++ Sbjct: 197 IVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 >4K0G-A nrPDB Length = 251 Score = 209 bits (531), Expect = 9e-55, Method: Composition-based stats. Identities = 58/229 (25%), Positives = 107/229 (46%), Gaps = 25/229 (10%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 +E+ VKA +G+ PFSQR + L K +T+ + ++ + + + P G++P Sbjct: 18 VELFVKAGSDGA-KIGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 76 Query: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDS-- 115 L + TD++ I LE +YP P E + G +IF F ++K+ + Sbjct: 77 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPAL 135 Query: 116 NDGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLY 159 ND E LL L+ L+N+L S F+ G ++ D +L PKL+ Sbjct: 136 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 195 Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWA 208 +QV ++ +++PE+F VH Y+ ++ + F T +++ + + Sbjct: 196 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYE 244 >2YV7-A nrPDB Length = 260 Score = 200 bits (508), Expect = 4e-52, Method: Composition-based stats. Identities = 46/211 (21%), Positives = 96/211 (45%), Gaps = 8/211 (3%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTL----EEKSLTYKIHLINLSDKPQWFLDISPQG 58 +E+ +KA+ G C F Q + L E K+++ K+ +++ P F Sbjct: 23 IELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEAT 82 Query: 59 KVPVLKIDDKWVTDSDVIVGILEEKYPDPP--LKTPAEFASVGSNIFGTFGTFLKSKDSN 116 P+L + + +++ I + + P E A++ N++ L KD Sbjct: 83 HPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIENLYVKLKLMLVKKD-- 140 Query: 117 DGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES 176 + +ALL L + +HL + + F+ G+ + D L P+L H++VA +F + +P Sbjct: 141 EAKNNALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTH 200 Query: 177 FPHVHNYMKTLFSLDSFEKTKTEEKYVISGW 207 + YM ++ LD+F ++ ++ +I+ + Sbjct: 201 LTALWRYMYHMYQLDAFTQSCPADQDIINHY 231 >3FY7-A nrPDB Length = 250 Score = 196 bits (499), Expect = 5e-51, Method: Composition-based stats. Identities = 54/225 (24%), Positives = 98/225 (43%), Gaps = 21/225 (9%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 L++ VKA+ + +G CP QR + L K + + + ++ P D +P ++P+ Sbjct: 26 LQLFVKASEDG-ESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPI 84 Query: 63 LKIDDKWVTDSDVIVGILEEKY--PDPPLKTP--AEFASVGSNIFGTFGTFLKS--KDSN 116 L D TD+ I LEE PD P P E + G+++F F F+K+ + Sbjct: 85 LLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQD 144 Query: 117 DGSEHALLVELEALENHLKS--------------HDGPFIAGERVSAVDLSLAPKLYHLQ 162 + LL L L+++L++ F+ G+R++ D SL PKL+ + Sbjct: 145 EALYQQLLRALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVD 204 Query: 163 VALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW 207 HF+ +P V Y+ + F+ T +++ + Sbjct: 205 TVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >5J5N-A nrPDB Length = 231 Score = 179 bits (454), Expect = 9e-46, Method: Composition-based stats. Identities = 46/199 (23%), Positives = 82/199 (41%), Gaps = 15/199 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGK-VPVLKIDDKWVTDSDVIVG 78 PF R L L EK + Y+ +L +K L ++P K +PVL + K V +S +IV Sbjct: 25 SPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQ 84 Query: 79 ILEEKYPDP-PLKTPAEFASVGSNIFGTF----------GTFLKSKDSNDGSEHALLVEL 127 ++E + D PL + S + F + K + + ++ + L Sbjct: 85 YIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDSL 144 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 + +E L D P+ GE + VD++L P Y A ++++ P + Y K Sbjct: 145 KLMEGEL--GDKPYFGGETIGYVDIALVP-FYSWFYAYETIGNFNIEAECPKMIAYCKRC 201 Query: 188 FSLDSFEKTKTEEKYVISG 206 ++ K + + V Sbjct: 202 LQKETVSKALEDPQKVYDF 220 >2VO4-A nrPDB Length = 219 Score = 178 bits (452), Expect = 1e-45, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 80/199 (40%), Gaps = 15/199 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVG 78 PF R + L EK + Y+ +L +K L ++P K+PVL + K + +S + V Sbjct: 13 SPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICESLIAVQ 72 Query: 79 ILEEKYPD-PPLKTPAEFASVGSNIFGTF----------GTFLKSKDSNDGSEHALLVEL 127 +EE + D PL + + + + + + + ++ + L Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAKKEFIEAL 132 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 + LE L D + G+ + VD++L P Y A F + ++ P + K Sbjct: 133 KLLEEQL--GDKTYFGGDNLGFVDIALVP-FYTWFKAYETFGTLNIESECPKFIAWAKRC 189 Query: 188 FSLDSFEKTKTEEKYVISG 206 +S K+ +++ V Sbjct: 190 LQKESVAKSLPDQQKVYEF 208 >4CHS-A nrPDB Length = 219 Score = 174 bits (442), Expect = 2e-44, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 79/199 (39%), Gaps = 15/199 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVG 78 PF R + L EK + Y+ +L +K L ++P K+PVL + K +++S + V Sbjct: 13 SPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISESLIAVQ 72 Query: 79 ILEEKYPD-PPLKTPAEFASVGSNIFGTF----------GTFLKSKDSNDGSEHALLVEL 127 +EE + D PL + + + + + + + ++ + L Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEKEAAKKEFIEAL 132 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 + LE L D + G+ + VD++L P Y F S ++ P + K Sbjct: 133 KLLEEQL--GDKTYFGGDNIGFVDIALVP-FYTWFKVYETFGSLNIENECPRFVAWAKRC 189 Query: 188 FSLDSFEKTKTEEKYVISG 206 +S K+ ++ V Sbjct: 190 LQKESVAKSLPDQHKVYEF 208 >5ECL-B nrPDB Length = 223 Score = 170 bits (431), Expect = 4e-43, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 82/199 (41%), Gaps = 15/199 (7%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGIL 80 F RA + L EK + ++ + S+K L +P K+PVL + K V +S +V + Sbjct: 21 FGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYV 80 Query: 81 EEKYPD-PPLKTPAEFASVGSNIFG----------TFGTFLKSKDSNDGSEHALLVELEA 129 +E +P+ P + + + F + K + + + + ++ Sbjct: 81 DEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKI 140 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 LE+ L D P+ G+ VD+SL A F ++S+ P + + K Sbjct: 141 LESEL--GDKPYFGGDSFGYVDISLIT-FSSWFQAYEKFGNFSIESESPKLIAWAKRCME 197 Query: 190 LDSFEKTKTEEKYVISGWA 208 +S K+ + + +++ A Sbjct: 198 KESVSKSLPDSEKIVAYAA 216 >5G5A-A nrPDB Length = 221 Score = 161 bits (408), Expect = 2e-40, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 82/197 (41%), Gaps = 15/197 (7%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGIL 80 F R + LEEK++ + +L +K L+++P K+PVL + V +S + + + Sbjct: 15 FGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVLIHNGNPVCESLIQIEYI 74 Query: 81 EEKYP-DPPLKTPAEFASVGSNIFGTFG----------TFLKSKDSNDGSEHALLVELEA 129 +E +P PL + + +G F + + ++ + + L+ Sbjct: 75 DEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEEHEAGKKEFIEILKT 134 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 LE+ L D + GE VD++L Y A F S+S+ P + + K Sbjct: 135 LESEL--GDKTYFGGETFGYVDIALI-GFYSWFEAYEKFGSFSIEAECPKLIAWGKRCVE 191 Query: 190 LDSFEKTKTEEKYVISG 206 +S K+ + + +I Sbjct: 192 RESVAKSLPDSEKIIKF 208 >3QAG-A nrPDB Length = 239 Score = 152 bits (385), Expect = 8e-38, Method: Composition-based stats. Identities = 43/180 (23%), Positives = 74/180 (41%), Gaps = 16/180 (8%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CP+S R L L+ K + +++ INL +KP+W+ P G +PVL+ + + +S + Sbjct: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESVIACE 91 Query: 79 ILEEKYPDPPL-----------KTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 L++ YP L K E S ++ L+S + + AL E Sbjct: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRESTNLKAALRQEF 151 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 LE L+ + F G +S +D L P L V + P + ++ + Sbjct: 152 SNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDV----YGILDCVSHTPALRLWISAM 207 >4J2F-A nrPDB Length = 223 Score = 150 bits (380), Expect = 3e-37, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 80/201 (39%), Gaps = 14/201 (6%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVG 78 PFS R + L+ K + Y+ +L +K L +P K+PVL K + +S +I+ Sbjct: 13 SPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILE 72 Query: 79 ILEEKYPDPPLKTPAEFASVGSNIFGTF---------GTFLKSKDSNDGSEHALLVELEA 129 L+E +P+ PL + + F F + + + L L+ Sbjct: 73 YLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEELEKAVKNCLEVLKT 132 Query: 130 LENH-LKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES--FPHVHNYMKT 186 +E H + D + G+++ VD++ + H + V ES FP +H + + Sbjct: 133 IEEHAMGVSDDKYFGGDKIGIVDIAFC-GIAHWLGVIEEVAGVKVLESQKFPRLHAWTEN 191 Query: 187 LFSLDSFEKTKTEEKYVISGW 207 ++ + + + + Sbjct: 192 FKEAPIIKENLPDRDQMTAFF 212 >2CZ2-A nrPDB Length = 223 Score = 150 bits (379), Expect = 4e-37, Method: Composition-based stats. Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 24/197 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINL-----SDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIV 77 S R + L K + Y+I INL + F ++P +VP LKID + S I+ Sbjct: 24 SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIM 83 Query: 78 GILEEKYPDPPLKTP-----------AEFASVGSNIFGTFGTFLKSKDSN--DGSEHALL 124 LEE P P L ++ + G + N ++ + Sbjct: 84 EYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVIT 143 Query: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 ALE L+S G + G+ VS D+ L P++ + FK P +P + + Sbjct: 144 SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA----ERFKVDLSP--YPTISHIN 197 Query: 185 KTLFSLDSFEKTKTEEK 201 K L +L+ F+ + + Sbjct: 198 KELLALEVFQVSHPRRQ 214 >6EP7-A nrPDB Length = 220 Score = 149 bits (377), Expect = 6e-37, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 79/195 (40%), Gaps = 15/195 (7%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVGIL 80 + R + LEEK + Y+ +LS+K L ++P K+PVL + K + +S + V + Sbjct: 15 YGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVLIHEGKPICESIIQVQYI 74 Query: 81 EEKYPD-PPLKTPAEFASVGSNIFGTFG----------TFLKSKDSNDGSEHALLVELEA 129 +E +PD P+ + + + + + +S + + ++ + L+ Sbjct: 75 DELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKALWSESGEKQEAAKIEFIEVLKT 134 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 L++ L D + G VD++ Y + S+ FP + + + Sbjct: 135 LDSEL--GDKYYFGGNEFGLVDIAFI-GFYSWFRTYEEVANLSIVLEFPKLMAWAQRCLK 191 Query: 190 LDSFEKTKTEEKYVI 204 +S K + V+ Sbjct: 192 RESVAKALPDSDKVL 206 >1FW1-A nrPDB Length = 216 Score = 148 bits (374), Expect = 1e-36, Method: Composition-based stats. Identities = 47/197 (23%), Positives = 79/197 (40%), Gaps = 24/197 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINL-----SDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIV 77 S R + L K + YK INL + F ++P +VP LKID + S I+ Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 78 GILEEKYPDPPLKTP-----------AEFASVGSNIFGTFGTFLKSKDSND--GSEHALL 124 LEE P P L ++ + G + + +++A+ Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAIT 136 Query: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 ALE L+S G + G+ V+ DL L P++ + FK P +P + + Sbjct: 137 CGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANA----ERFKVDLTP--YPTISSIN 190 Query: 185 KTLFSLDSFEKTKTEEK 201 K L L++F+ + + Sbjct: 191 KRLLVLEAFQVSHPCRQ 207 >3LFL-A nrPDB Length = 240 Score = 147 bits (371), Expect = 4e-36, Method: Composition-based stats. Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 16/194 (8%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CPF++R L L+ K + +++ INL +KP+WF +P G VPVL+ + + +S + Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 79 ILEEKYPDPPLKTPAEF--------ASVGSNIFGTFGTFLKSKDSND--GSEHALLVELE 128 L+E YP L + + S + G+F++S++ D G + E Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 LE L + F G +S +D + P L+ K + P + +M + Sbjct: 152 KLE-VLTNKKTTFFGGNSISMIDYLIWPWFERLEA----MKLNECVDHTPKLKLWMAAMK 206 Query: 189 SLDSFEKTKTEEKY 202 + T EK Sbjct: 207 EDPTVSALLTSEKD 220 >1E6B-A nrPDB Length = 221 Score = 146 bits (368), Expect = 7e-36, Method: Composition-based stats. Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 25/199 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQ---WFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 + R + L K L Y+ +NL Q F I+P G VP L D + DS I+ Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMY 79 Query: 80 LEEKYPDPPL------KTPAEFASV-----GSNIFGTFGTF------LKSKDSNDGSEHA 122 L+EKYP+PPL K + ++ G + ++ +A Sbjct: 80 LDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAWVNNA 139 Query: 123 LLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHN 182 + ALE L + G G+ + DL LAP+++ A+ F+ P +P + Sbjct: 140 ITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIH---GAINRFQINMEP--YPTLAK 194 Query: 183 YMKTLFSLDSFEKTKTEEK 201 ++ L +F+ E++ Sbjct: 195 CYESYNELPAFQNALPEKQ 213 >4PQI-A nrPDB Length = 241 Score = 145 bits (367), Expect = 9e-36, Method: Composition-based stats. Identities = 50/203 (24%), Positives = 90/203 (44%), Gaps = 17/203 (8%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINL--SDKPQWFL-DISPQGKVPVLKIDDKWVTDSDVI 76 CPF+QR +T K L +I L+ L ++P W+ + P KVP L+ + K +S + Sbjct: 41 CPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLDL 100 Query: 77 VGILEEKYPDPPLKT--------PAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELE 128 + LE + P L E S GT T K + + + Sbjct: 101 IKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAKEAG-----PAFD 155 Query: 129 ALENHL-KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 LEN L K DGPF G+ S VD++ P + L + L + + + +++ + Sbjct: 156 HLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEEV 215 Query: 188 FSLDSFEKTKTEEKYVISGWAPK 210 ++++++TKT+ K ++ + + Sbjct: 216 NKIEAYKQTKTDPKELVEFYKKR 238 >3WD6-A nrPDB Length = 256 Score = 145 bits (366), Expect = 1e-35, Method: Composition-based stats. Identities = 46/186 (24%), Positives = 77/186 (41%), Gaps = 10/186 (5%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CP++QR +L L K + Y++ I+L DKP+W S KVP ++I +D + +S V V Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAIEIAEDVTIYESLVTVE 97 Query: 79 ILEEKYPDPPLKTPAEF--------ASVGSNIFGTFGTFLKSKDS-NDGSEHALLVELEA 129 L+E YP PL + I F LK D+ N+ A L+ Sbjct: 98 YLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQSLFIKILKFSDTVNEEHVAAYHKALDF 157 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 ++ LK+ F+ G D + P L+ + P + + Y+ + Sbjct: 158 IQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDERVRLEPSKYSLLLEYIDNMLK 217 Query: 190 LDSFEK 195 + + Sbjct: 218 DSAVSQ 223 >3RBT-A nrPDB Length = 246 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 47/205 (22%), Positives = 84/205 (40%), Gaps = 14/205 (6%) Query: 16 HLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI----DDKWVT 71 H+ P+ R LL LE K + Y+++ ++ P+WF +P+ K+PVL+I D+++ Sbjct: 31 HVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLF 90 Query: 72 DSDVIVGILEEKYPDPPLKTPAEFASVGSNIF-GTFGTFLKSK----DSNDGS-EHALLV 125 +S VI L+EKY L + + + F +K D+N ++ Sbjct: 91 ESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLECFDTNFAFGSEQIIQ 150 Query: 126 ELEALENHLKSHDGPFIAGERVSAVDLSLAPK---LYHLQVALGHFKSWSVPESFPHVHN 182 LE E L + + G R +D + P LY L+ K FP+ + Sbjct: 151 TLEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLRCVNDR-KFVEKKSLFPNFAD 209 Query: 183 YMKTLFSLDSFEKTKTEEKYVISGW 207 + + D +K + + Sbjct: 210 WGDQMQLDDIVKKHAHSPQEYFDYY 234 >4QQ7-A nrPDB Length = 207 Score = 140 bits (354), Expect = 3e-34, Method: Composition-based stats. Identities = 50/201 (24%), Positives = 91/201 (45%), Gaps = 25/201 (12%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 CPFSQR L L EK + ++I ++L +KP+ ++P G+VP+L D + +S++I Sbjct: 14 CPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINEY 73 Query: 80 LEEKYPDPPLKTPAEFA---------SVGSNIFGTFGTF--LKSKDSNDGSEHALLVELE 128 ++E++P P L + +F T K K + E A L Sbjct: 74 IDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARL---- 129 Query: 129 ALENHLKSH-----DGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNY 183 A+ + L ++ GE S +D+++AP L+ L H+ + P + Y Sbjct: 130 AIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLD----HYGIELSKNAAP-LMKY 184 Query: 184 MKTLFSLDSFEKTKTEEKYVI 204 + +FS ++ + T + V+ Sbjct: 185 AERIFSRPAYIEALTPSEKVM 205 >4AGS-A nrPDB Length = 471 Score = 135 bits (341), Expect = 9e-33, Method: Composition-based stats. Identities = 47/205 (22%), Positives = 83/205 (40%), Gaps = 20/205 (9%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDK-PQWFLDISPQGKVPVLKI---DDKWVTDSDV 75 CPF R + EK ++Y + L ++ PQW+ I+P+ VP L++ D +++ +S + Sbjct: 35 CPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADKRFMFESML 94 Query: 76 IVGILEEK-YPDPPL-------KTPAEF--ASVGSNIFGTFGTFLKSKDSNDGSEHALLV 125 I L+ P L + EF A VG I G +D G + + Sbjct: 95 IAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLL---RDPLSGEKRKAMD 151 Query: 126 ELEALENHLKSHD---GPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHN 182 + A + L + + GP+ + D++L P L L+ AL ++ + V P + Sbjct: 152 DNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDVFCKAPRMKA 211 Query: 183 YMKTLFSLDSFEKTKTEEKYVISGW 207 S +T I + Sbjct: 212 LWAAAAQRASVRETSPTAAQCIENY 236 Score = 92.4 bits (228), Expect = 1e-19, Method: Composition-based stats. Identities = 41/189 (21%), Positives = 72/189 (38%), Gaps = 19/189 (10%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 CPF RA L E + I + L +P+W+ I+P+ VP L + V +S +IV Sbjct: 261 CPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQ 320 Query: 79 ILEEKYPDPPLKTPAEFAS-----------VGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 ++ P A G + G ++ + E Sbjct: 321 YIDCVATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQWAAGE- 379 Query: 128 EALENHLKSH---DGPFIAGERVSAVDLSLAPKLYHLQVALGHF-KSWSVPESFPHVHNY 183 LE L H +GPF G+R++A D+++ P L + + F + + FP ++ Sbjct: 380 --LEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGYDLFAHFPLLNGL 437 Query: 184 MKTLFSLDS 192 + + Sbjct: 438 AEAGMATPE 446 >3NIV-A nrPDB Length = 222 Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats. Identities = 45/203 (22%), Positives = 78/203 (38%), Gaps = 32/203 (15%) Query: 23 SQRALLTLEEKSLTYK---IHLINLSDKPQ--WFLDISPQGKVPVLKIDDKWVTDSDVIV 77 R + L K + Y+ +HL+N + + I+PQ VP L I+ + ++ S I+ Sbjct: 14 CYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQILSQSMAII 73 Query: 78 GILEEKYPDPPLKTPAEF-----------ASVGSNIFGTFGTFLKSKDSNDGSE------ 120 LEE +P+ PL F + + + K+ + +E Sbjct: 74 DYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQFNANEEQVLEW 133 Query: 121 --HALLVELEALENHLKS--HDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES 176 H L +A E L + D P G V D+ L P++Y+ HF S Sbjct: 134 YHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHRF--HFDM----AS 187 Query: 177 FPHVHNYMKTLFSLDSFEKTKTE 199 +P ++ + +L +F E Sbjct: 188 YPIINEINEYCLTLPAFHDAAPE 210 >1OYJ-A nrPDB Length = 231 Score = 120 bits (302), Expect = 4e-28, Method: Composition-based stats. Identities = 43/207 (20%), Positives = 76/207 (36%), Gaps = 21/207 (10%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKIDDKWVTDSDVIVG 78 PF QR + + EK L ++ +L +K L +P K+PVL + V++S VI+ Sbjct: 15 SPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLHAGRPVSESLVILQ 74 Query: 79 ILEEKYPDPPLKTPA---------------EFAS--VGSNIFGTFGTFLK-SKDSNDGSE 120 L++ +P P P F + V ++ + + + Sbjct: 75 YLDDAFPGTPHLLPPANSGDADAAYARATARFWADYVDRKLYDCGSRLWRLKGEPQAAAG 134 Query: 121 HALLVELEALENHLKSHD-GPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 + L LE L + G R+ VD++L P + +SV E P Sbjct: 135 REMAEILRTLEAELGDREFFGGGGGGRLGFVDVALVPFTA-WFYSYERCGGFSVEEVAPR 193 Query: 180 VHNYMKTLFSLDSFEKTKTEEKYVISG 206 + + + +DS K + V Sbjct: 194 LAAWARRCGRIDSVVKHLPSPEKVYDF 220 >3UAR-A nrPDB Length = 227 Score = 110 bits (276), Expect = 4e-25, Method: Composition-based stats. Identities = 43/196 (21%), Positives = 83/196 (42%), Gaps = 25/196 (12%) Query: 28 LTLEEKSLTYKIHLINLSDKP----QWFLDISPQGKVPVLK-IDDKWVTDSDVIVGILEE 82 + L E L +++ ++L K FL ++P+G VP L+ D + +T+ VI+ L + Sbjct: 18 IVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLDDGQVLTEDQVILQYLAD 77 Query: 83 KYPDPPLKTPAE----------FASVGSNIFGTFGTFLKSKDSNDGSEHALL---VELEA 129 P+ L P+ A + + I TFG F + + AL L+ Sbjct: 78 LKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFWNPESPEASKQIALGLLSRRLDY 137 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 +E+ L++ GP++ G+R S D L+ L + K +P + Y++ + Sbjct: 138 VEDRLEA-GGPWLMGDRYSVADAYLSTVLGW----CEYLKIDL--SKWPRILAYLERNQA 190 Query: 190 LDSFEKTKTEEKYVIS 205 + + E + + Sbjct: 191 RPAVQAAMKAEGLIQA 206 >2YV9-A nrPDB Length = 291 Score = 110 bits (274), Expect = 5e-25, Method: Composition-based stats. Identities = 42/236 (17%), Positives = 97/236 (41%), Gaps = 28/236 (11%) Query: 3 LEICVKAAVGAPDHLGDCPFSQRALL---TLEEKSL-TYKIHLINLSDKPQWFLDISPQG 58 LE+ VKA+ +G F Q + L E + ++ +N++ + F Sbjct: 20 LELYVKASGIDARRIGADLFCQEFWMELYALYEIGVARVEVKTVNVN--SEAFKKNFLGA 77 Query: 59 KVPVLKIDDKWVT--DSDVIVG---ILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSK 113 + P++ ++K +T D+ I G L +++ P + N++ F FL++K Sbjct: 78 QPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVPLFEKDPSAEKRIENLYRNFKLFLRAK 137 Query: 114 DSNDGSEHA-----------------LLVELEALENHLKSHDGPFIAGERVSAVDLSLAP 156 D + + +L ++ L ++ G ++ D L P Sbjct: 138 VEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMP 197 Query: 157 KLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 +L+H+++ + +P +F H+ Y+ T + +F ++ ++ +I + ++N Sbjct: 198 RLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPADQDIIHHYKEQMN 253 >4MPF-A nrPDB Length = 266 Score = 109 bits (272), Expect = 9e-25, Method: Composition-based stats. Identities = 47/208 (22%), Positives = 81/208 (38%), Gaps = 40/208 (19%) Query: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQ 57 M LE+ + + ++ + ++ ++L K + FL I+ Sbjct: 23 MGLELFLDLVSQPSRA---------VYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSL 73 Query: 58 GKVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASV----------GSNIFGTFG 107 GK+P LK D +T+S I+ L KY P P++ + I GTFG Sbjct: 74 GKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFG 133 Query: 108 TFL------------KSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLA 155 L K+ + + A+ L+ LE+ D PF+AG++V+ DL Sbjct: 134 IPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLG-DRPFLAGQQVTLADLMAL 192 Query: 156 PKLYHLQVALGHFKSWSVPESFPHVHNY 183 +L VAL + + E P + + Sbjct: 193 EELMQ-PVAL----GYELFEGRPRLAAW 215 >4YH2-A nrPDB Length = 222 Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 31/202 (15%) Query: 17 LGDCPFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDS 73 L P + LTL +LTY+ +++ + +L+ +PQ VP L+ D ++ DS Sbjct: 9 LDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDS 68 Query: 74 DVIVGIL-------EEKYPDPPLKTPA-------EFASVGSNIFGTF--GTFLKSKDSND 117 I+ L + YP PLK E V +N + + + Sbjct: 69 HAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVP 128 Query: 118 GSEHALLVEL-EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ--VALGHFKSWSVP 174 + ++E+ + +E LK D +IAG +++ D SL + L+ VAL K Sbjct: 129 KERYDAIIEIYDFVETFLKGQD--YIAGNQLTIADFSLVSSVASLEAFVALDTTK----- 181 Query: 175 ESFPHVHNYMKTLFSLDSFEKT 196 +P + ++K L L +E+ Sbjct: 182 --YPRIGAWIKKLEQLPYYEEA 201 >4IGJ-A nrPDB Length = 242 Score = 107 bits (267), Expect = 4e-24, Method: Composition-based stats. Identities = 43/202 (21%), Positives = 79/202 (39%), Gaps = 29/202 (14%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKID----DKWVTDSDV 75 + R L L K L Y+ ++L + Q+ +P +VPVL+++ + S Sbjct: 36 AWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMA 95 Query: 76 IVGILEEKYPDPPLKTP-----------AEFASVGSNIFGTFGTFLKSKDSNDGSEHA-- 122 I+ LEE++P+P L P AE + G+ ++ G + Sbjct: 96 ILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPGWDREWA 155 Query: 123 ---LLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 + L ALE ++ G F G+ + D L P+LY+ + F P +P Sbjct: 156 RFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNAR----RFGLDLEP--YPT 209 Query: 180 VHNYMKTLFSLDSFEKTKTEEK 201 + + +L F+ + + Sbjct: 210 LRRVDEACAALAPFQAAHPDRQ 231 >1GWC-A nrPDB Length = 230 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 48/218 (22%), Positives = 84/218 (38%), Gaps = 21/218 (9%) Query: 9 AAVGAPDHLGD--CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISP-QGKVPVLKI 65 A LG PF R L L K L+Y+ +L K + L +P K+PVL Sbjct: 2 AGGDDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVLIH 61 Query: 66 DDKWVTDSDVIVGILEEKY--PDPPLKTPAEF---------ASVGSNIFGTFGTFLKSKD 114 + V +S +I+ ++E + P L + A V + + +L+ K Sbjct: 62 NGAPVCESMIILQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKT 121 Query: 115 SNDGSE--HALLVELEALENHLKSHDG--PFIAGERVSAVDLSLAPKLYHLQV--ALGHF 168 + SE + LE L+ F G+ V VD++L L ++V AL Sbjct: 122 EEEKSEGKKQAFAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEALSGD 181 Query: 169 KSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISG 206 K + P + +++ LD+ + + ++ Sbjct: 182 KIFDA-AKTPLLAAWVERFIELDAAKAALPDVGRLLEF 218 >2JL4-A nrPDB Length = 213 Score = 99.3 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 42/203 (20%), Positives = 71/203 (34%), Gaps = 30/203 (14%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 S R + L K + Y+ ++L + F ++PQ VP L + + S I+ Sbjct: 13 SHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQVLIQSPAIIEW 72 Query: 80 LEEKYPDPPLKTP---------AEFASVGSNIFG----TFGTFLKS------KDSNDGSE 120 LEE+YP P L A A VG +I +L+ N Sbjct: 73 LEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKTFGADEAAINAWCG 132 Query: 121 HALLVELEALENHLKS--HDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFP 178 + +A E L G + G+ + D L P++ + F+ P +P Sbjct: 133 TWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESAR----RFQVDLTP--YP 186 Query: 179 HVHNYMKTLFSLDSFEKTKTEEK 201 + LD+F + + Sbjct: 187 LIRAVDAACGELDAFRRAAPAAQ 209 >4PNG-A nrPDB Length = 229 Score = 98.1 bits (243), Expect = 2e-21, Method: Composition-based stats. Identities = 41/200 (20%), Positives = 73/200 (36%), Gaps = 27/200 (13%) Query: 17 LGDCPFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDS 73 L P + LTL + Y+ +N K + FL +PQ VP L+ D ++ DS Sbjct: 15 LEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDS 74 Query: 74 DVIVGILEEKYPDPPLKTPAEFAS---------------VGSNIFGTFGTFLKSKDSNDG 118 I+ L KY P + + + K + Sbjct: 75 HAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIP 134 Query: 119 SEH--ALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES 176 E A++ + LE L +D ++AG +++ D S+ + L+V + Sbjct: 135 KERYDAIIEVYDFLEKFLAGND--YVAGNQLTIADFSIISTVSSLEVFVK-----VDTTK 187 Query: 177 FPHVHNYMKTLFSLDSFEKT 196 +P + + K L L +E+ Sbjct: 188 YPRIAAWFKRLQKLPYYEEA 207 >4PXO-A nrPDB Length = 238 Score = 96.6 bits (239), Expect = 6e-21, Method: Composition-based stats. Identities = 50/203 (24%), Positives = 78/203 (38%), Gaps = 33/203 (16%) Query: 25 RALLTLEEKSLTYKIHLINL----SDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVGI 79 R + L K + Y+ ++L KP FL I+PQG VP L D +T S I+ Sbjct: 37 RVRIALNLKGIAYEEVFLDLDAGDQHKP-DFLAINPQGAVPALFDGDGPPLTQSLAILDY 95 Query: 80 LEEKYPDPPLKTP-----------AEFASVGSNIF--GTFGTFLKS------KDSNDGSE 120 LEE PL A+ + ++ TFL + + Sbjct: 96 LEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMENYGLPRERMLEFLR 155 Query: 121 HALLVELEALENHL--KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFP 178 +A + L+ LE L ++ G F G+ VS DL L L V G F ++P Sbjct: 156 NAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLI----SLWVGTGIFGID--TAAYP 209 Query: 179 HVHNYMKTLFSLDSFEKTKTEEK 201 V + + +LD+ + + Sbjct: 210 TVKRISEEVLALDAVARAHPLRQ 232 >3TOT-A nrPDB Length = 226 Score = 95.0 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 71/202 (35%), Gaps = 20/202 (9%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLK-IDDKWVTDSDVIV 77 P++++ + L EK + Y+ L ++ + +P GKVP L D + DS VI Sbjct: 10 ASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIA 69 Query: 78 GILEEKYPDPPLKTPAEFASVGSNIFG-----------TFGTFLKSKDSNDGSEHALLVE 126 + P L P+ V + + SE + + Sbjct: 70 EYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSESWITRQ 129 Query: 127 LEALENHLKS-----HDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVH 181 ++ LK+ D + G ++ D+++ L +L E ++ Sbjct: 130 HHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDF---RQPQVDWREQHANLA 186 Query: 182 NYMKTLFSLDSFEKTKTEEKYV 203 + + SF +T+ + + + Sbjct: 187 AFYTRIEKRPSFLETQPQAENL 208 >3VWX-A nrPDB Length = 222 Score = 95.0 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 27/200 (13%) Query: 17 LGDCPFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDS 73 + P + LLTL+ +L ++ ++NL K + +L +PQ VP L+ D + DS Sbjct: 9 IDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDS 68 Query: 74 DVIVGILEEKYPDPPLKTPAE-----------FASVGSNIFGTFG-----TFLKSKDSND 117 I+ L KY P + + G G F +++ Sbjct: 69 HAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIP 128 Query: 118 GSEHA-LLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES 176 + ++ LE+ LK + ++AG+ ++ D S+ + L VA Sbjct: 129 QHQIDSIVESYGFLESFLK--NNKYMAGDHLTIADFSIVTSVTSL-VAFAEIDQ----SK 181 Query: 177 FPHVHNYMKTLFSLDSFEKT 196 FP + ++K+L SL +E+ Sbjct: 182 FPKLSAWLKSLQSLPFYEEA 201 >1AW9-A nrPDB Length = 216 Score = 93.1 bits (230), Expect = 8e-20, Method: Composition-based stats. Identities = 41/205 (20%), Positives = 72/205 (35%), Gaps = 31/205 (15%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKIDDKWVTDSDVI 76 P R L EK L ++I ++L+ K FL ++P G++P L D+ + +S I Sbjct: 11 SPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAI 70 Query: 77 VGILEEKY--------PDPPLKTPAEFA----------SVGSNIFGTFGTFLKSKDSNDG 118 + KY P E + +F L + Sbjct: 71 NRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRPLLGGAPDAA 130 Query: 119 ----SEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVP 174 L L+ E HL ++AG+ + D + A L + L + Sbjct: 131 VVDKHAEQLAKVLDVYEAHL--ARNKYLAGDEFTLADANHASYL----LYLSKTPKAGLV 184 Query: 175 ESFPHVHNYMKTLFSLDSFEKTKTE 199 + PHV + + + + +F+KT Sbjct: 185 AARPHVKAWWEAIVARPAFQKTVAA 209 >3LG6-A nrPDB Length = 235 Score = 92.4 bits (228), Expect = 1e-19, Method: Composition-based stats. Identities = 33/211 (15%), Positives = 64/211 (30%), Gaps = 39/211 (18%) Query: 25 RALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKID-----------DKWV 70 R + KS+ Y H +NL + ++P VP+L + + Sbjct: 23 RLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNTVSPSSASFSI 82 Query: 71 TDSDVIVGILEEKYPDP--PLKTP-------------AEFASVGSNIFGTFGTFLKSK-- 113 S + LEE P PL P + K K Sbjct: 83 GQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQPVTNLKIQKKVKAL 142 Query: 114 --DSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSW 171 D S A+E L+ G F G+ ++ D+ L P ++ + + Sbjct: 143 DGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAAERVGMDLARF 202 Query: 172 SVPESFPHVHNYMKTLFSLDSFEKTKTEEKY 202 + + + + ++ +K +++ Sbjct: 203 PITK------RVFEEMLKEEAVQKAHWQKQE 227 >3UBL-A nrPDB Length = 242 Score = 87.7 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 22/172 (12%) Query: 22 FSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 + + L + EK L Y+ I S + + FL ISP GK+PVL++D K++ +S I+ L+ Sbjct: 14 YVNKVKLGILEKGLEYEQIRIAPSQE-EDFLKISPMGKIPVLEMDGKFIFESGAILEFLD 72 Query: 82 EKYPDPPLKTPAEFASVGS--NIFGTFGTFL-------------KSKDSNDGSEHALLVE 126 +P P P + I T+L S + + L+ Sbjct: 73 TIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEIVEEVHSTLVKG 132 Query: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFP 178 ++AL+ ++ P+IAG + D S HL V + + P + P Sbjct: 133 IKALQRVVRFS--PYIAGNVFTLADCS---GFAHLSVLDEELRPF-YPNNHP 178 >6JWK-A nrPDB Length = 222 Score = 85.0 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 69/204 (33%), Gaps = 32/204 (15%) Query: 23 SQRALLTLEEKSLTYKIHLINLSD----KPQWFLDISPQGKVPVLKI-DDKWVTDSDVIV 77 S R + L K L Y++ +NL +P +P G +P L D + + S I+ Sbjct: 12 SYRVRIALALKGLDYQVVPVNLRQGEQLRPAD-RQRNPMGALPTLVDADGRRFSQSLAII 70 Query: 78 GILEEKYPDPPLKTPAE-----------FASVGSNIFGTFGTF--------LKSKDSNDG 118 L+ P+P L + + + ++D Sbjct: 71 DYLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVLGIDAEDRQRW 130 Query: 119 SEHALLVELEALENHLKSHDG-PFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESF 177 H + L A E L H F AG V+ L P+L + + P + Sbjct: 131 YAHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANAR----RMGCDLAP--Y 184 Query: 178 PHVHNYMKTLFSLDSFEKTKTEEK 201 P + +L++F++ E + Sbjct: 185 PALLELEGRCLALEAFQRASPERQ 208 >5F06-A nrPDB Length = 216 Score = 83.5 bits (205), Expect = 6e-17, Method: Composition-based stats. Identities = 48/198 (24%), Positives = 78/198 (39%), Gaps = 33/198 (16%) Query: 25 RALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 R L L EK+L +++ ++L K FL +P G++P L+ DD + +S I + Sbjct: 15 RVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIA 74 Query: 82 EKYPDP-----PLKTPAEFASV---------------GSNIFGTFGTFLKSKDSN----D 117 EK+ + E ASV +F L+ + D Sbjct: 75 EKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMVAPLRGNSPDQTIID 134 Query: 118 GSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESF 177 + L L+ E L S ++AG+ S DL P Y+L + SV Sbjct: 135 DNVEKLGKVLDIYEAKLSS--TKYLAGDFYSLADLHHLPYTYYL----MKTPAASVVNER 188 Query: 178 PHVHNYMKTLFSLDSFEK 195 PHV + + + S +F+K Sbjct: 189 PHVKAWWEDISSRPAFKK 206 >1JLV-A nrPDB Length = 209 Score = 83.5 bits (205), Expect = 6e-17, Method: Composition-based stats. Identities = 39/187 (20%), Positives = 69/187 (36%), Gaps = 27/187 (14%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQGKVPVLKIDDKWVTDSD 74 G P + +T + + L NL FL I+PQ +P L + + +S Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLVDNGFALWESR 66 Query: 75 VIVGILEEKY---PDPPLKTPAEFASVGSNIFGTFGTFLK------------SKDSNDGS 119 I L EKY K P + A V ++ GT + + +N + Sbjct: 67 AICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAKQPANAEN 126 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E + ++ L L H ++AG+ ++ DL++ + VA +PH Sbjct: 127 EKKMKDAVDFLNTFLDGH--KYVAGDSLTIADLTVLATVSTYDVAGFEL------AKYPH 178 Query: 180 VHNYMKT 186 V + + Sbjct: 179 VAAWYER 185 >3IBH-A nrPDB Length = 233 Score = 83.5 bits (205), Expect = 6e-17, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 69/204 (33%), Gaps = 36/204 (17%) Query: 21 PFSQRALLTLEEKSL--TYKIHLINLS---DKPQWFLDISPQGKVPVLK-IDDKWVTDSD 74 P+ R + L EK++ + + INL K FL + G VPVL+ D + + Sbjct: 28 PYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECT 87 Query: 75 VIVGILE--EKYPDPPLKTPAEFAS-------VGSNIFGTFGTFL--------------K 111 I ++ + P KTP E + + + Sbjct: 88 AITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQ 147 Query: 112 SKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSW 171 +K+ L + + L + P++AG+ S D+++ L Sbjct: 148 NKEWGLRQRDKALHGMHYFDTVL--RERPYVAGDSFSMADITVIAGL-----IFAAIVKL 200 Query: 172 SVPESFPHVHNYMKTLFSLDSFEK 195 VPE + + K + S +K Sbjct: 201 QVPEECEALRAWYKRMQQRPSVKK 224 >4MK3-A nrPDB Length = 226 Score = 83.1 bits (204), Expect = 8e-17, Method: Composition-based stats. Identities = 33/196 (16%), Positives = 70/196 (35%), Gaps = 20/196 (10%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 P++++ + L EK + Y++ N+ +P GKVP L + D V DS VI Sbjct: 31 SPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAVFDSRVIAE 90 Query: 79 ILEEKYPDPPLKTPAEFASVGSNIFG-----------TFGTFLKSKDSNDGSEHALLVEL 127 + P L + + + + ++ SE + + Sbjct: 91 YADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESERSESWVQRQR 150 Query: 128 EALENHLKS-----HDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHN 182 ++ L + D + G + D+++ L +L F + + P++ Sbjct: 151 SKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLDF---RFPDIAWRDRHPNLVA 207 Query: 183 YMKTLFSLDSFEKTKT 198 + + + SF T+ Sbjct: 208 FQEKIEKRQSFIDTEP 223 >1PN9-A nrPDB Length = 209 Score = 83.1 bits (204), Expect = 9e-17, Method: Composition-based stats. Identities = 39/188 (20%), Positives = 69/188 (36%), Gaps = 27/188 (14%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDSD 74 G P + +T + + L +L FL ++PQ +P L + + +S Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLVDNGFALWESR 66 Query: 75 VIVGILEEKY---PDPPLKTPAEFASVGSNIFGTFGTFLK------------SKDSNDGS 119 I L EKY K P + A V ++ GT + + +N + Sbjct: 67 AIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAKQPANPEN 126 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E + + L L+ + + AG ++ DLSLA + +VA F +P+ Sbjct: 127 EKKMKDAVGFLNTFLEGQE--YAAGNDLTIADLSLAATIATYEVAGFDF------APYPN 178 Query: 180 VHNYMKTL 187 V + Sbjct: 179 VAAWFARC 186 >5ZWP-A nrPDB Length = 208 Score = 82.3 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 41/183 (22%), Positives = 72/183 (39%), Gaps = 26/183 (14%) Query: 23 SQRALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 + L+T + + L+NL FL I+PQ +P L D + +S I+ Sbjct: 12 CRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGDFALWESRAIMVY 71 Query: 80 LEEKYPDPP---LKTPAEFASVGSNIFGTFGTFLKS------------KDSNDGSEHALL 124 L EKY K P + A + ++ GT KS ++ + Sbjct: 72 LVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPADPELFKKIE 131 Query: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 + L LK H+ + AG+ ++ DL+L + +VA S+ + +P+V + Sbjct: 132 TAFDFLNTFLKGHE--YAAGDSLTVADLALLASVSTFEVA-----SFDI-SKYPNVAKWY 183 Query: 185 KTL 187 L Sbjct: 184 ANL 186 >2IL3-A nrPDB Length = 221 Score = 80.4 bits (197), Expect = 5e-16, Method: Composition-based stats. Identities = 40/197 (20%), Positives = 68/197 (34%), Gaps = 29/197 (14%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDSDVI 76 P + LT + L + INL F+ ++PQ +PVL + +T+S I Sbjct: 12 SPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVLDDNGTIITESHAI 71 Query: 77 VGILEEKYPDPPLKTPAE-----------------FASVGSNIFGTFGTFLKSKDSNDGS 119 + L KY P + + IF F KS D Sbjct: 72 MIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPEDRV 131 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 E+ + E LE+ L F+AG ++ D S + + + P Sbjct: 132 EY-VQKSYELLEDTLVDD---FVAGPTMTIADFSCISTISSIMGVVP-----LEQSKHPR 182 Query: 180 VHNYMKTLFSLDSFEKT 196 ++ ++ L L +E+ Sbjct: 183 IYAWIDRLKQLPYYEEA 199 >5EY6-A nrPDB Length = 217 Score = 79.6 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 32/198 (16%) Query: 25 RALLTLEEKSLTYKIHLINLSD---KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 R L+TL EK + ++I +++S K +L I P G+VP + + + +S I + Sbjct: 17 RVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESISLFESRSICRYVC 76 Query: 82 EKYPDPPLK-----TPAEFASVGSNIFGTFGTFLKSKDSN-------------------D 117 EKY D K P E AS+ + +F S + Sbjct: 77 EKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVIK 136 Query: 118 GSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESF 177 +E L L+ E L + F+AG+ + DLS P +L A + S Sbjct: 137 QNEEKLGKVLDIYEQRL--GESRFLAGDEFTFADLSHLPNGDYLVNATDKGHLF---TSR 191 Query: 178 PHVHNYMKTLFSLDSFEK 195 +V + + +S++K Sbjct: 192 ENVGRWWNEISDRESWKK 209 >1F2E-A nrPDB Length = 201 Score = 78.5 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 36/196 (18%), Positives = 68/196 (34%), Gaps = 36/196 (18%) Query: 28 LTLEEKSLTYKIHLINLSDKP----QWFLDISPQGKVPVLKID-DKWVTDSDVIVGILEE 82 + L E ++ ++L+ + + FL ++P GKVP L +D + +T++ I+ + + Sbjct: 16 IALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIAD 75 Query: 83 KYPDPPLKTP----------AEFASVGSNIFGTFGTFLKSKDSNDGSEHALLV---ELEA 129 + P L + + +GS F S++ A L A Sbjct: 76 QNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNHLAA 135 Query: 130 LENHLKSHDGPFIAGERVSAVDLSL-----APKLYHLQVALGHFKSWSVPESFPHVHNYM 184 L+ L D AG S D+ L P + +A +P + Y Sbjct: 136 LDKELAGRD--HYAGNAFSVADIYLYVMLGWPAYVGIDMAA-----------YPALGAYA 182 Query: 185 KTLFSLDSFEKTKTEE 200 + + E Sbjct: 183 GKIAQRPAVGAALKAE 198 >3MAK-A nrPDB Length = 209 Score = 78.5 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 36/188 (19%), Positives = 72/188 (38%), Gaps = 27/188 (14%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKIDDKWVTDSD 74 G P + ++T + + L+NL FL I+PQ +P L + + +S Sbjct: 9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDNGFALWESR 67 Query: 75 VIVGILEEKYPD---PPLKTPAEFASVGSNIFGTFGTFLKS------------KDSNDGS 119 I L EKY K P + A + ++ GT +S ++ + Sbjct: 68 AIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPEA 127 Query: 120 EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPH 179 + E L L+ D + AG+ ++ D++L + +VA + + + + Sbjct: 128 FKKIEAAFEFLNTFLEGQD--YAAGDSLTVADIALVATVSTFEVA-----KFEI-SKYAN 179 Query: 180 VHNYMKTL 187 V+ + + Sbjct: 180 VNRWYENA 187 >2PMT-A nrPDB Length = 203 Score = 78.1 bits (191), Expect = 2e-15, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 65/189 (34%), Gaps = 28/189 (14%) Query: 28 LTLEEKSLTYKIHLINLSDKP----QWFLDISPQGKVPVLK-IDDKWVTDSDVIVGILEE 82 + L E L + I I+L K + FL I+P+G+VPVL+ + +T+ IV L + Sbjct: 16 IVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTEGVAIVQYLAD 75 Query: 83 KYPDPPLKTPAE----------FASVGSNIFGTFGTFLKSKDSN---DGSEHALLVELEA 129 PD L P + + S + + S ++ L + Sbjct: 76 LKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSSDTPESYLPVVKNKLKSKFVY 135 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHL-QVALGHFKSWSVPESFPHVHNYMKTLF 188 + + L + G+ + D L VAL H+ +Y+ + Sbjct: 136 INDVL--SKQKCVCGDHFTVADAYLFTLSQWAPHVALD-------LTDLSHLQDYLARIA 186 Query: 189 SLDSFEKTK 197 + Sbjct: 187 QRPNVHSAL 195 >2GDR-A nrPDB Length = 202 Score = 78.1 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 34/192 (17%), Positives = 75/192 (39%), Gaps = 28/192 (14%) Query: 28 LTLEEKSLTYKIHLINLSDKP----QWFLDISPQGKVPVLK-IDDKWVTDSDVIVGILEE 82 + L E L +++ ++L+ K Q +L+++P G VP L+ D + +T+ IV + + Sbjct: 16 IALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTEGPAIVQYVAD 75 Query: 83 KYPDPPLKTPAE----------FASVGSNIFGTFGTFLKSKDSNDGS---EHALLVELEA 129 + P L + S + +F S++ +L L Sbjct: 76 QVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPLFNPASSDEWKNAVRQSLNTRLGQ 135 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSV-PESFPHVHNYMKTLF 188 + L+ P++ G+++S D+ L V LG ++ +P + + + Sbjct: 136 VARQLEHA--PYLLGDQLSVADIYL-------FVVLGWSAYVNIDLSPWPSLQAFQGRVG 186 Query: 189 SLDSFEKTKTEE 200 ++ + E Sbjct: 187 GREAVQSALRAE 198 >5F07-A nrPDB Length = 213 Score = 77.3 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 71/205 (34%), Gaps = 33/205 (16%) Query: 17 LGDCPFSQRALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQGKVPVLKIDDKWVTDS 73 + CP QR + L EK + + + ++L K FL P G+VPV++ D + +S Sbjct: 9 VAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFES 66 Query: 74 DVIVGILEEKYPDPPL------------------KTPAEFASVGSNIFGTFGTFLKSKDS 115 I+ KY D F + NI + Sbjct: 67 RAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQ 126 Query: 116 NDGS-----EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKS 170 D E L L+ E L ++AG+ + DLS P + + Sbjct: 127 GDSELVRTYEEKLEKVLDVYEKRL--SKSKYLAGDSFTLADLSHLPA---TRYLVNEAGL 181 Query: 171 WSVPESFPHVHNYMKTLFSLDSFEK 195 + + ++ + + + S +++K Sbjct: 182 GHLVKDRKKLNAWWEDISSRPAWKK 206 >5A5K-A nrPDB Length = 212 Score = 76.9 bits (188), Expect = 5e-15, Method: Composition-based stats. Identities = 39/200 (19%), Positives = 69/200 (34%), Gaps = 35/200 (17%) Query: 25 RALLTLEEKSLTYKIHLINLSD---KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 R L+ L EK+L +++ + L D K + FL +P G+VP + D + +S I + Sbjct: 17 RVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIA 76 Query: 82 EKYP--------------------------DPPLKTPAEFASVGSNIFGTFGTFLKSKDS 115 +Y + P IF + + Sbjct: 77 HRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAV 136 Query: 116 NDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPE 175 E L L+ E LK + ++AGE + DL P + +L + Sbjct: 137 VAEEEAKLAKVLDVYEARLK--EFKYLAGETFTLTDLHHIPAIQYLLGTPTK----KLFT 190 Query: 176 SFPHVHNYMKTLFSLDSFEK 195 P V+ ++ + + EK Sbjct: 191 ERPRVNEWVAEITKRPASEK 210 >3GH6-A nrPDB Length = 210 Score = 76.6 bits (187), Expect = 8e-15, Method: Composition-based stats. Identities = 37/193 (19%), Positives = 70/193 (36%), Gaps = 30/193 (15%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLI-NLSDK---PQWFLDISPQGKVPVLKIDDKWVTDS 73 G P + L+T + + + I N + +L I+PQ +P L + +S Sbjct: 8 GSAP-CRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWES 66 Query: 74 DVIVGILEEKYPDPPLKTPAE-----------FASVGSNIFGTFGTF-----LKSKDSND 117 I+ L EKY P + + +G+ ++ +F + K +N+ Sbjct: 67 RAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGT-LYKSFSEYYYPQIFLKKPANE 125 Query: 118 GSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESF 177 + + V E L L+ + AG S D++ + VA FK + Sbjct: 126 ENYKKIEVAFEFLNTFLEGQ--TYSAGGDYSLADIAFLATVSTFDVAGFDFK------RY 177 Query: 178 PHVHNYMKTLFSL 190 +V + + L Sbjct: 178 ANVARWYENAKKL 190 >1V2A-A nrPDB Length = 210 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 38/201 (18%), Positives = 74/201 (36%), Gaps = 28/201 (13%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQ--WFLDISPQGKVPVLKIDDKWVTDSDVIV 77 P Q A+L ++ +T + N+ D + ++PQ +P L + V +S IV Sbjct: 9 SPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLVDNGHVVWESYAIV 68 Query: 78 GILEEKYPDPPLKTPA--------------EFASVGSNIFGTFGTFLKSKDSNDGSEHAL 123 L E Y P + ++ I +K + +D L Sbjct: 69 LYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQPSDEQMEKL 128 Query: 124 LVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNY 183 L+ LE + + + A + ++ D+ L + AL K P FPH+ + Sbjct: 129 KGALDLLEQFVT--ERAYAAADHLTVADICLLGTV----TALNWLKHDLEP--FPHIRAW 180 Query: 184 MKTLFSL----DSFEKTKTEE 200 ++ + + + F K ++ Sbjct: 181 LERVRAEMPDYEEFSKQVADD 201 >5F0G-A nrPDB Length = 215 Score = 74.2 bits (181), Expect = 4e-14, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 66/183 (36%), Gaps = 26/183 (14%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 + ++ + L L+N + F+ ++PQ +P L + + +S I Sbjct: 12 CRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVY 71 Query: 80 LEEKYPDPPLK---TPAEFASVGSNIFGTFGTFLK------------SKDSNDGSEHALL 124 L EKY P + A + ++ GT + K +D + Sbjct: 72 LVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTGKPGSDEDLKRIE 131 Query: 125 VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYM 184 L+ L+ + ++AG++++ D+++ + +V+ F + +V + Sbjct: 132 TAFGFLDTFLEGQE--YVAGDQLTVADIAILSTVSTFEVSEFDF------SKYSNVSRWY 183 Query: 185 KTL 187 Sbjct: 184 DNA 186 >6F05-A nrPDB Length = 215 Score = 73.9 bits (180), Expect = 5e-14, Method: Composition-based stats. Identities = 45/201 (22%), Positives = 82/201 (40%), Gaps = 31/201 (15%) Query: 25 RALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 RAL+TL EK + ++ ++L K +L + P G VP + D + +S ++ + Sbjct: 15 RALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYVA 74 Query: 82 EKY--PDPPLK--------------------TPAEFASVGSNI-FGTFGTFLKSKDSNDG 118 EKY P L ++ +I F + F + Sbjct: 75 EKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIKE 134 Query: 119 SEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFP 178 SE L L+ E HL ++AG+ VS DL+ P +L +G K++ + + Sbjct: 135 SEEKLAGVLDVYEAHL--SKSKYLAGDFVSLADLAHLPFTDYLVGPIG--KAYMI-KDRK 189 Query: 179 HVHNYMKTLFSLDSFEKTKTE 199 HV + + S ++++T + Sbjct: 190 HVSAWWDDISSRPAWKETVAK 210 >1N2A-A nrPDB Length = 201 Score = 72.7 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 68/191 (35%), Gaps = 26/191 (13%) Query: 28 LTLEEKSLTYKIHLINLSDK----PQWFLDISPQGKVPVLKIDDKWVT-DSDVIVGILEE 82 +TL E + + ++L K + ++P+G+VP L +DD + + I+ L + Sbjct: 16 ITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDDGTLLTEGVAIMQYLAD 75 Query: 83 KYPDPPLKTPAEFAS----------VGSNIFGTFGTFLKSKDSND---GSEHALLVELEA 129 PD L P S + + + F + + L +L+ Sbjct: 76 SVPDRQLLAPVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQY 135 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 + LK D +I G+R + D L L + E H+ +M+ + Sbjct: 136 VNEALK--DEHWICGQRFTIADAYLFTVLRWA------YAVKLNLEGLEHIAAFMQRMAE 187 Query: 190 LDSFEKTKTEE 200 + + E Sbjct: 188 RPEVQDALSAE 198 >3M3M-A nrPDB Length = 210 Score = 72.7 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 34/189 (17%), Positives = 71/189 (37%), Gaps = 28/189 (14%) Query: 23 SQRALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKI-DDKWVTDSDVIVG 78 + L L L Y+ +++ + + FL +P GK+PVL++ D + +S+ I+ Sbjct: 15 CYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDGTCLWESNAILN 74 Query: 79 ILEEKYP----DPPLKTPAEFASVGS----NIFGTFGTFLKSKD--SNDGSEHALL---- 124 L + +P L+T + F++ + + E L Sbjct: 75 FLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGLPEERREEYLKLHKR 134 Query: 125 --VELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHN 182 L+ +E L P++ GE S D++L + + + +P + Sbjct: 135 GYKALDVMEKQL--SRTPYLVGEHYSIADIALYAYTHVADE-----GGFDL-SRYPGIQA 186 Query: 183 YMKTLFSLD 191 +M+ + S Sbjct: 187 WMQRVQSHP 195 >5NR1-A nrPDB Length = 228 Score = 72.7 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 36/207 (17%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDK----WVTDSDVI 76 P S++ L L EK L + + + P F ++P G PVL + ++ I Sbjct: 14 PASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRAI 73 Query: 77 VGILEEKYPDPPL--KTPAEFASVGSNIFGTF------------------GTFLKSKDSN 116 + +EE +PPL + PAE A + F L+ + Sbjct: 74 LEHIEETETEPPLLGRDPAERAEA-RRLLQWFDRKFDNEVNGFLLHEKMEKRLLRMGAPD 132 Query: 117 DGS----EHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWS 172 + AL + L +E+ L++ D ++AG R+S D + A L + +F Sbjct: 133 LAALRQGREALRMHLGYIESLLQTRD--WLAGRRMSLADFAAAAHLS----VIDYFGDVP 186 Query: 173 VPESFPHVHNYMKTLFSLDSFEKTKTE 199 + F + L S F + Sbjct: 187 W-KDFQAAKTWYMKLKSRPCFRPILAD 212 >2C3Q-A nrPDB Length = 247 Score = 72.3 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 36/193 (18%), Positives = 68/193 (35%), Gaps = 32/193 (16%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDKWVTDSDVIVGI 79 + + ++ + +++ +++L F ++P KVP LK D +T+S I+ Sbjct: 21 CRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLY 80 Query: 80 LEEKYPDPPLKTPAEFASVG-----------------------SNIFGTFGTFLKSKDSN 116 L KY P P + + +F F S + Sbjct: 81 LTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTL 140 Query: 117 DGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPES 176 + L V L+ LE+ + F+ G +S DL +L H A V E Sbjct: 141 AATLAELDVTLQLLEDKFL-QNKAFLTGPHISLADLVAITELMHPVGA-----GCQVFEG 194 Query: 177 FPHVHNYMKTLFS 189 P + + + + + Sbjct: 195 RPKLATWRQRVEA 207 >3PR8-A nrPDB Length = 229 Score = 72.3 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 33/193 (17%), Positives = 70/193 (36%), Gaps = 20/193 (10%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYP 85 L L EK LT++ PQ L++SP+GKVPVL+ + +++++ VI+ +E+ Sbjct: 17 VKLALLEKGLTFEEVTFYGGQAPQA-LEVSPRGKVPVLETEHGFLSETSVILDYIEQTQG 75 Query: 86 DPPLKTPAEF-ASVGSNIFGTFGTFLKSKDS----------------NDGSEHALLVELE 128 L F + + +++ + + LL Sbjct: 76 GKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVEPLIKEKARADLLAGFA 135 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 L+ P++AGE+++ DL + + FP ++ + Sbjct: 136 TLKR--NGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDFLADFPQAKALLQLMG 193 Query: 189 SLDSFEKTKTEEK 201 + +++ Sbjct: 194 ENPHMPRILADKE 206 >4RI7-A nrPDB Length = 215 Score = 71.9 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 43/207 (20%), Positives = 74/207 (35%), Gaps = 39/207 (18%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSD---KPQWFLDISPQGKVPVLKIDDKWVTDSDVI 76 C R L TL EK + + + I+LS K +L I P G+VP K + + +S I Sbjct: 13 CTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAI 72 Query: 77 VGILEEKYPDPPLKTPAEFASVGSNIFGT--------------------------FGTFL 110 + +KY D K+ G++I F + Sbjct: 73 CRYICDKYADKGNKSL-----YGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSSVP 127 Query: 111 KSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKS 170 + + L L+ E L F+AG+ S DLS P + + Sbjct: 128 VDEALIKKNVDKLAKVLDIYEQKL--GQTRFLAGDEFSFADLSHLP---NGDYLVNSTDK 182 Query: 171 WSVPESFPHVHNYMKTLFSLDSFEKTK 197 + S +V+ + + + +S++K Sbjct: 183 GYLFTSRKNVNRWWTEISNRESWKKVL 209 >1AXD-A nrPDB Length = 209 Score = 71.5 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 72/195 (36%), Gaps = 30/195 (15%) Query: 25 RALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILE 81 R LEE Y+I IN K L +P G+VP L+ D ++ +S I Sbjct: 16 RCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGDLYLFESRAICKYAA 75 Query: 82 EKYPDPPLKTPAEFASVGSNIFGT--------------FGTFLKSKDSNDGSEHALLVEL 127 K L+ + +++ F + + + L Sbjct: 76 RKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDENL 135 Query: 128 EALENHLKSHDG-----PFIAGERVSAVDLSLAPKLYHLQVALGHFKS--WSVPESFPHV 180 E L+ L+ ++ ++AG+ +S D L H+ V L F + SV +++PHV Sbjct: 136 EKLKKVLEVYEARLTKCKYLAGDFLSLAD------LNHVSVTLCLFATPYASVLDAYPHV 189 Query: 181 HNYMKTLFSLDSFEK 195 + L S +K Sbjct: 190 KAWWSGLMERPSVQK 204 >3R2Q-A nrPDB Length = 202 Score = 69.6 bits (169), Expect = 9e-13, Method: Composition-based stats. Identities = 45/201 (22%), Positives = 80/201 (39%), Gaps = 26/201 (12%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLK-IDDKWVTDSDVIVG 78 PF ++ + L EK +T++ + +P GKVPVL + + DS +I Sbjct: 9 SPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAE 68 Query: 79 ILE--EKYPDPPLKTPAEFASV--------GSNIFGTFGTFLKSKDSNDGSEHALLVELE 128 +E P + P E V G G +++ + SE LL + E Sbjct: 69 YIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQRE 128 Query: 129 ALENHLKSHDGPFIAG----ERVSAVDLSLAPKLYHLQVALGHFK----SWSVPESFPHV 180 + L +G + G + V+ +++A V +F+ W V PH+ Sbjct: 129 KINRSLDVLEGYLVDGTLKTDTVNLATIAIA-----CAVGYLNFRRVAPGWCV--DRPHL 181 Query: 181 HNYMKTLFSLDSFEKTKTEEK 201 ++ LFS +SF +T+ + Sbjct: 182 VKLVENLFSRESFARTEPPKA 202 >5F05-A nrPDB Length = 212 Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 70/200 (35%), Gaps = 31/200 (15%) Query: 24 QRALLTLEEKSLTYKIHLINLS---DKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGIL 80 QR L TL EK + +++ +NL K + + ++P G+VP D + +S I + Sbjct: 15 QRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYV 74 Query: 81 EEKYP----------------------DPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDG 118 +Y + P+ V +F Sbjct: 75 AHQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKPVFGLPTDAALVAE 134 Query: 119 SEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFP 178 +E L L+ E L ++A + + DL P + AL S + +S P Sbjct: 135 TEVTLGKVLDVYEARLSQS--KYLASDSFTLADLHHLPNIQ----ALLGTPSKKLFDSRP 188 Query: 179 HVHNYMKTLFSLDSFEKTKT 198 HV ++ ++ ++ K Sbjct: 189 HVSAWVASITGRPAWGKVLA 208 >3M8N-A nrPDB Length = 225 Score = 69.2 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 76/192 (39%), Gaps = 29/192 (15%) Query: 23 SQRALLTLEEKSLTYKIHLINLSD---KPQWFLDISPQGKVPVLKID-DKWVTDSDVIVG 78 S + L L Y+ +++ + FL +P G+VP+L+ +++ +S+ I+ Sbjct: 15 SYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAPGRYLAESNAILW 74 Query: 79 ILE---EKYPDPPLKTPAEFA-------SVGSNIFGTFGTFLKSKDSNDGSEHALLV--- 125 L PD + ++ NI + K D HAL Sbjct: 75 YLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQTHALEDWLE 134 Query: 126 ----ELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVH 181 L+ +ENHLK++D + A +++ D++L + + + +FP V+ Sbjct: 135 RGYAALQVMENHLKTND--YFAAGQLTIADIALYGYTHVADQ-----CDFDL-STFPAVN 186 Query: 182 NYMKTLFSLDSF 193 +++ + F Sbjct: 187 AWLRRVEQTPGF 198 >3GX0-A nrPDB Length = 215 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 40/206 (19%), Positives = 70/206 (33%), Gaps = 33/206 (16%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDKPQ---WFLDISPQGKVPVLKI-----DDKWV-- 70 P + L LEE L Y++ ++L Q FL ISP K+P + + + Sbjct: 10 PNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPADGGEPLSL 69 Query: 71 TDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELEA- 129 +S I+ L EK E A+ +F G N HA + Sbjct: 70 FESGAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQTIPYA 129 Query: 130 --------------LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPE 175 L L++ P++ GE S D++ P + + Sbjct: 130 IERYQVETQRLYHVLNKRLENS--PWLGGENYSIADIACWPWVNAW------TRQRIDLA 181 Query: 176 SFPHVHNYMKTLFSLDSFEKTKTEEK 201 +P V N+ + + S + + + + Sbjct: 182 MYPAVKNWHERIRSRPATGQALLKAQ 207 >3C8E-A nrPDB Length = 288 Score = 65.4 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 40/204 (19%), Positives = 79/204 (38%), Gaps = 31/204 (15%) Query: 21 PFSQRALLTLEEK------SLTYKIHLINLSDKPQW---FLDISPQGKVPVLKIDDK--- 68 P Q+ + LEE Y LI + D Q+ F++++P K+P L+ Sbjct: 53 PNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPP 112 Query: 69 -WVTDSDVIVGILEEKYPDPPLKTPAE----------FASVGSNIFGTFGTF-----LKS 112 V +S I+ L EK+ + A+ + G FG F +K Sbjct: 113 IRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKI 172 Query: 113 KDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGH-FKSW 171 + + + L+ L+ L H F+AG+ + D+++ P ++ + + + Sbjct: 173 EYAINRFTMEAKRLLDVLDKQLAQH--KFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEF 230 Query: 172 SVPESFPHVHNYMKTLFSLDSFEK 195 S+ HV + K + + ++ Sbjct: 231 LDAGSYKHVQRWAKEVGERPAVKR 254 >4FQU-A nrPDB Length = 313 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 47/247 (19%), Positives = 87/247 (35%), Gaps = 56/247 (22%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLI----------------------NLSDKPQWFLDISP 56 CP++ R L+ K L ++ + + + + + Sbjct: 52 ACPWAHRVLIMRALKGLE-EMISVSMVNAYMGENGWTFLPGDDVVPDSINGADYLYQVYT 110 Query: 57 QG--------KVPVL--KIDDKWVT-DSDVIVGILEEKYPD----PPLKTPAEFASVGSN 101 +P+L K++ + + +S I+ IL + D P PAEF Sbjct: 111 AADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDR 170 Query: 102 IFGTFGTFLKSK-------DSNDGSEHA---LLVELEALENHLKSHDGPFIAGERVSAVD 151 I L + + + E A L L+ LE HL + ++ G+R++ D Sbjct: 171 INARVYETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLTGRE--WLVGDRLTEAD 228 Query: 152 LSLAPKLYHLQVAL-GHFK-SWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW-- 207 + L P L GHFK + +P++ + L S + T ++ + + Sbjct: 229 IRLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLASHERVAPTI-NLRHAKAHYYG 287 Query: 208 -APKVNP 213 P VNP Sbjct: 288 SHPSVNP 294 >1U3I-A nrPDB Length = 211 Score = 64.2 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 38/184 (20%), Positives = 73/184 (39%), Gaps = 23/184 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-----KWVTDSDVIV 77 ++ +TL + Y+ I+ D P+ I P G++P +K+ D KW+ +S I Sbjct: 17 AESIRMTLVAAGVDYEDERISFQDWPKIKPTI-PGGRLPAVKVTDDHGHVKWMLESLAIA 75 Query: 78 GILEEKYPDPPLKTPAEFASVGSNIFGT-------FGTFLKSKDSNDGSEHALLVE---- 126 + +K+ +T E+ SV I T +K ++ + +L Sbjct: 76 RYMAKKH-HMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITKEILNGKVPV 134 Query: 127 -LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMK 185 + LK G G++V+ DL L + H+ F + +P +H + + Sbjct: 135 LFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGF----LTGKYPEIHKHRE 190 Query: 186 TLFS 189 L + Sbjct: 191 NLLA 194 >3LSZ-A nrPDB Length = 225 Score = 63.8 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 71/204 (34%), Gaps = 41/204 (20%) Query: 23 SQRALLTLEEKSLTYKIHLI--------------NLSDKPQWFLDISPQGKVPVLKIDDK 68 + R L L E L ++ + L+ +L ++P G++P L+ + Sbjct: 13 ASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQIPCLEEEGL 72 Query: 69 WVTDSDVIVGILEEKY---------PDPPLKTP-AEFASVGSNIFGTFGTFLK------- 111 +T+S I + P+ L + FA+ ++ Sbjct: 73 ILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQRSGGGTS 132 Query: 112 --SKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFK 169 + + + L L LE H + D ++ G R + DL+LA L+ H Sbjct: 133 PEGQAAIAIAAERLRRPLARLERHFAAED--YLVGGRFTVADLNLA---ETLRYGQAHPA 187 Query: 170 SWSVPESFPHVHNYMKTLFSLDSF 193 + E FP V ++ S +F Sbjct: 188 ---LLEPFPAVAAWLDRCQSRPAF 208 >4IKH-A nrPDB Length = 244 Score = 63.5 bits (153), Expect = 6e-11, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 75/210 (35%), Gaps = 35/210 (16%) Query: 21 PFSQRALLTLEEKSLTYKIHLINLSDK---PQWFLDISPQGKVPVLKI----DDKWV--T 71 P + + LEE L Y+ H ++ + FL +SP K+P + D+ + Sbjct: 31 PNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALF 90 Query: 72 DSDVIVGILEEKYPDPPLKTPAEFASVGSNI-------------FGTFGTFLKS------ 112 +S I+ L +K E A+ I FG G F K Sbjct: 91 ESGAILIYLADK---SGQLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFNKFAGREYE 147 Query: 113 -KDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSW 171 K + + L L+ HL + +I GER + D++ P + +L + Sbjct: 148 DKRPLERYVNEAKRLLGVLDKHLGGRE--WIMGERYTIADIATFPWIRNLIGFYEAGELV 205 Query: 172 SVPESFPHVHNYMKTLFSLDSFEKTKTEEK 201 + ++FP V + + + + K Sbjct: 206 GI-DNFPEVKRVLAKFVARPAVIRGLEIPK 234 >1YQ1-A nrPDB Length = 208 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 32/187 (17%), Positives = 60/187 (32%), Gaps = 23/187 (12%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYP 85 L + ++ +N D +P ++PVL ID + S I+ L K+ Sbjct: 18 IRLLFHLAGVQFEEVRMNPDQTWLDIKDSTPMKQLPVLNIDGFELPQSGAILRYLARKF- 76 Query: 86 DPPLKTPAEFA------SVGSNIFGTFGTF------LKSKDSNDGSEHALL-----VELE 128 KTP E A + + F F KS + + Sbjct: 77 GFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSAEEVEKFRSEFFLPARNTYFN 136 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 L L+ + F+ G ++ DL + L L ++ + F + + + Sbjct: 137 ILNGLLEKSNSGFLIGSDITFADLVVVDNLLTL----KNYGLFD-ESEFTKLAALREKVN 191 Query: 189 SLDSFEK 195 S ++ Sbjct: 192 SYPGIKE 198 >3M1G-A nrPDB Length = 362 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 55/247 (22%), Positives = 89/247 (36%), Gaps = 56/247 (22%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLINLSDKPQ----WFLDISPQGKVPVLKI--------- 65 CP++ R ++T L + + L+ W D+ P PVL+I Sbjct: 69 ACPWAHRTVITRRLLGLE-NVISLGLTGPTHDVRSWTFDLDPNHLDPVLQIPRLQDAYFN 127 Query: 66 ------------------DDKWVTD---SDVIVGILEEK---YPDPPLKTPAEF----AS 97 K VT+ S I LE K P PAE A Sbjct: 128 RFPDYPRGITVPALVEESSKKVVTNDYPSITIDFNLEWKQFHREGAPNLYPAELREEMAP 187 Query: 98 VGSNIFGTFGT------FLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVD 151 V IF F S+++++ + L V L+ LE+ L ++ G+ ++ D Sbjct: 188 VMKRIFTEVNNGVYRTGFAGSQEAHNEAYKRLWVALDWLEDRL--STRRYLMGDHITEAD 245 Query: 152 LSLAPKLYHLQVAL-GHFK-SWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW-- 207 + L P L GHFK + P++ Y++ LF F T T+ + + Sbjct: 246 IRLYPTLVRFDAVYHGHFKCGRNKITEMPNLWGYLRDLFQTPGFGDT-TDFTEIKQHYYI 304 Query: 208 -APKVNP 213 ++NP Sbjct: 305 THAEINP 311 >2CA8-A nrPDB Length = 211 Score = 62.3 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 39/184 (21%), Positives = 75/184 (40%), Gaps = 23/184 (12%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-----KWVTDSDVIV 77 ++ +TL + Y+ I+ D P+ I P G++P +KI D KW+ +S I Sbjct: 17 AESIRMTLVAAGVNYEDERISFQDWPKIKPTI-PGGRLPAVKITDNHGHVKWMVESLAIA 75 Query: 78 GILEEKYPDPPLKTPAEFASVGSNIFGT-------FGTFLKSKDSNDGSEHALLVE---- 126 + +K+ T E+ +V I + T +K ++ +L Sbjct: 76 RYMAKKH-HMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQKIIKEILNGKVPV 134 Query: 127 -LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMK 185 L+ + LK+ G G++V+ DL L + H+ F + +P +H + + Sbjct: 135 LLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEF----LTGKYPEIHKHRE 190 Query: 186 TLFS 189 L + Sbjct: 191 NLLA 194 >2GLR-A nrPDB Length = 209 Score = 60.4 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 33/193 (17%), Positives = 71/193 (36%), Gaps = 19/193 (9%) Query: 23 SQRALLTLEEKSLTY--KIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGIL 80 + + L ++ ++ ++ I+ + G++P + D + S+ I+ L Sbjct: 14 CEAMRMLLADQGQSWKEEVVTIDTWMQG-LLKPTCLYGQLPKFEDGDLTLYQSNAILRHL 72 Query: 81 EEKYPDPPLKTPAEFASVGS------NIFGTFGTFLKSKDSNDGSE--HALLVELEALEN 132 K E A + ++ G + T + + N ++ AL L+ E Sbjct: 73 GRSL-GLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPGHLKPFET 131 Query: 133 HL--KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL 190 L FI G+++S D +L L QV ++FP + Y+ L + Sbjct: 132 LLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAP-----GCLDNFPLLSAYVARLSAR 186 Query: 191 DSFEKTKTEEKYV 203 + + ++V Sbjct: 187 PKIKAFLSSPEHV 199 >6GZF-A nrPDB Length = 341 Score = 59.6 bits (143), Expect = 9e-10, Method: Composition-based stats. Identities = 39/249 (15%), Positives = 84/249 (33%), Gaps = 59/249 (23%) Query: 19 DCPFSQRALLTLEEKSLTY----------------------------KIHLINLSDKPQW 50 CP++ R L+T K L +H ++ + Sbjct: 63 ACPWAHRTLVTRTLKGLEDAISVSVVDPYRAEDGWQFTPEKEGCTHDHVHDVDYLR--EL 120 Query: 51 FLDISP----QGKVPVL---KIDDKWVTDSDVIVGILEEKYPDPPL----KTPAEFASVG 99 ++ +P + VPVL + D +S+ I+ + + ++ + P + Sbjct: 121 YVRAAPDVTCRVTVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYPEGYQEKV 180 Query: 100 SNIFGTFGTFLKSK----------DSNDGSEHALLVELEALENHLKSHDGPFIAGERVSA 149 I + + + D + L L ++ L D ++AG+R++ Sbjct: 181 DQIIDNIYEPINNGVYRAGFATEQEPYDEAVAELFGALAHWDDVL--ADQRYLAGDRLTE 238 Query: 150 VDLSLAPKLYHLQVAL-GHF-KSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW 207 D+++ L HF + F ++ Y++ L+ +T E ++ + Sbjct: 239 ADIAMFTTLVRFDNVYHTHFMCNVQYIREFDNLWPYLRDLYQTHGIAETV-EMDHITEHY 297 Query: 208 ---APKVNP 213 P VNP Sbjct: 298 YTTHPDVNP 306 >4Q5F-A nrPDB Length = 218 Score = 59.2 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 37/186 (19%), Positives = 68/186 (36%), Gaps = 25/186 (13%) Query: 27 LLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYPD 86 L + + ++ + + D P +P G++P+L++D + + S I L ++ Sbjct: 31 RLIFHQAGVKFEDNRLKREDWPA-LKPKTPFGQLPLLEVDGEVLAQSAAIYRYLGRQF-G 88 Query: 87 PPLKTPAEFASVGSNIFGTFGTF-------------LKSKDSNDGSEH----ALLVELEA 129 KTP E A V S IF F F + D + A L Sbjct: 89 LAGKTPMEEAQVDS-IFDQFKDFMAELRPCFRVLAGFEEGDKEKVLKEVAVPARDKHLPL 147 Query: 130 LENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFS 189 LE L ++ G+ V+ DL + L + + F + Y++ + Sbjct: 148 LEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDF-----LSGHLQLKKYIEHVRE 202 Query: 190 LDSFEK 195 L + +K Sbjct: 203 LPNIKK 208 >1G6W-A nrPDB Length = 261 Score = 58.1 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 38/245 (15%), Positives = 71/245 (28%), Gaps = 71/245 (28%) Query: 18 GDCPFSQR-------ALLTLEEKSLTYKIHLINL---SDKPQWFLDISPQGKVPVLKI-- 65 G FS R + L E Y ++ + F+ ++P +VP L Sbjct: 20 GYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHG 79 Query: 66 -DDKWVTDSDVIVGILEEKY---PDPPLKTPAEFASVGS--------------------- 100 D+ + +S I+ L KY PL + A Sbjct: 80 MDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALH 139 Query: 101 -------NIFGTF--------GTFLKSKDSNDGSEHALLVELEALENHLKSHDGP----- 140 I + + + AL++EL+ EN G Sbjct: 140 FRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDT-ENAAAYSAGTTPMSQ 198 Query: 141 --------FIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDS 192 ++ G++++ DL+ P + ++ FP V+ + K + + Sbjct: 199 SRFFDYPVWLVGDKLTIADLAFVPWNNVVDRI-----GINIKIEFPEVYKWTKHMMRRPA 253 Query: 193 FEKTK 197 K Sbjct: 254 VIKAL 258 >4MDC-A nrPDB Length = 252 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 42/213 (19%), Positives = 68/213 (31%), Gaps = 39/213 (18%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-KWVTDSDVIV 77 P S+ L L E ++ + + FL ++P G +PV D + + + +I Sbjct: 31 MSPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCGATIIS 90 Query: 78 GILEEK----YPDPPLKTPAEFASVG----------------------SNIFGTFGTFLK 111 L+E D L F IF T + Sbjct: 91 EYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRERIFKLQMTPDQ 150 Query: 112 SKDSNDGSEHALLVELEALENHLK-----SHDGPFIAGERVSAVDLSLAPKLYHLQVALG 166 + D L + H+K + P++AG+R+S DL+ A + L Sbjct: 151 GGGAPDS--KILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAAAISVLDYLGE 208 Query: 167 HFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTE 199 WS P + + L S SF E Sbjct: 209 --IDWS---DAPTAKEWYQRLKSRPSFRPLLAE 236 >1VF1-A nrPDB Length = 229 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 36/184 (19%), Positives = 66/184 (35%), Gaps = 20/184 (10%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLD--ISPQGKVPVLKIDDKWVTDSDVIVGILEEK 83 L + ++ + ++ + L I +VP+++ID + + I+ + K Sbjct: 19 IRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEIDGMKLVQTRAILNYIAGK 78 Query: 84 YPDPPLKTPAEFASVGSNIFGT------------FGTFLKSKDSNDGSEHALLVELEALE 131 Y + K E A + + GT K K E A A E Sbjct: 79 Y-NLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQCAFVVEKATSRYFPAYE 137 Query: 132 NHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLD 191 LK H F+ G R+S D+ L + ++ K FP + + K + S+ Sbjct: 138 KVLKDHGQDFLVGNRLSWADIHLLEAILMVEE-----KKSDALSGFPLLQAFKKRISSIP 192 Query: 192 SFEK 195 + +K Sbjct: 193 TIKK 196 >2PVQ-A nrPDB Length = 201 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 67/190 (35%), Gaps = 24/190 (12%) Query: 28 LTLEEKSLTYKIHLINLSDKPQ----WFLDISPQGKVPVLKID-DKWVTDSDVIVGIL-- 80 + L E L Y++ ++L K + ++P+G VP L++ +T + I+ + Sbjct: 16 IILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPGTVITQNAAILQYIGD 75 Query: 81 -EEKYPDPPLKTPAEFASVG------SNIFGTFGTFLKS---KDSNDGSEHALLVELEAL 130 + P E A + S++ F +++ G + L L Sbjct: 76 HSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANINRRLGQL 135 Query: 131 ENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL 190 E L + + G+ + D + A + V ++P + + + Sbjct: 136 EAMLSDKNA-YWLGDDFTQPD-AYASVIIGWGV-----GQKLDLSAYPKALKLRERVLAR 188 Query: 191 DSFEKTKTEE 200 + +K EE Sbjct: 189 PNVQKAFKEE 198 >3BBY-A nrPDB Length = 215 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 57/164 (34%), Gaps = 23/164 (14%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGK---VPVLKIDDKWVTDSDVI 76 P+ A + L+EK L++ I I+L G+ VP+L+IDD +++S I Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAI 76 Query: 77 VGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKS-------------------KDSND 117 LE+++ P + +L+S K Sbjct: 77 AEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGAKKAPLT 136 Query: 118 GSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHL 161 A +L A+ HL P + G D LA + L Sbjct: 137 AEGKASAEKLFAMAEHLLVLGQPNLFG-EWCIADTDLALMINRL 179 >18GS-A nrPDB Length = 210 Score = 54.2 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 31/193 (16%), Positives = 66/193 (34%), Gaps = 19/193 (9%) Query: 23 SQRALLTLEEKSLTY--KIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGIL 80 + L ++ ++ ++ + + G++P + D + S+ I+ L Sbjct: 15 CAALRMLLADQGQSWKEEVVTVETWQEGS-LKASCLYGQLPKFQDGDLTLYQSNTILRHL 73 Query: 81 EEKYPDPPLKTPAEFASVGS------NIFGTFGTFL--KSKDSNDGSEHALLVELEALEN 132 K E A V ++ + + + + D AL +L+ E Sbjct: 74 GRTL-GLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFET 132 Query: 133 HL--KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL 190 L FI G+++S D +L L +V ++FP + Y+ L + Sbjct: 133 LLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAP-----GCLDAFPLLSAYVGRLSAR 187 Query: 191 DSFEKTKTEEKYV 203 + +YV Sbjct: 188 PKLKAFLASPEYV 200 >1F3B-A nrPDB Length = 222 Score = 54.2 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 70/187 (37%), Gaps = 26/187 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG-----KVPVLKIDDKWVTDSDVIVGIL 80 L + ++ P+ + G +VP+++ID + + I+ + Sbjct: 18 IRWLLAAAGVEFE---EKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYI 74 Query: 81 EEKYPDPPLKTPAEFASVGS------NIFGTFGTFLKSKDSNDGSEHALLVE------LE 128 KY D K E A + ++ G + ++ AL + L Sbjct: 75 ATKY-DLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRYLP 133 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 A E LKSH ++ G R++ VD+ L L +++ S+ FP + + + Sbjct: 134 AFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEF-----DASLLTPFPLLKAFKSRIS 188 Query: 189 SLDSFEK 195 SL + +K Sbjct: 189 SLPNVKK 195 >3PPU-A nrPDB Length = 352 Score = 53.4 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 36/245 (14%), Positives = 84/245 (34%), Gaps = 59/245 (24%) Query: 19 DCPFSQRALLTLEEKSLT----------------YKIHLINL------------SDKPQW 50 CP++ R L+ + K L + ++ Sbjct: 85 ACPWATRTLIVRKLKGLEDFIGVTVVSPRMGSNGWPFANVDPFPAADSDPLNNAQHVKDL 144 Query: 51 FLDISP----QGKVPVL--KIDDKWVT-DSDVIVGILEEKYPDPPLKTPAEFASVGSNIF 103 +L + P + VPVL K V +S I+ + + + A+ ++ Sbjct: 145 YLKVKPDYDGRFTVPVLWDKHTGTIVNNESSEIIRMFNTAFNHLLPEDKAKLDLYPESLR 204 Query: 104 GTF-----------------GTFLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGER 146 F ++ + + + L L+ LE L+ D ++ G + Sbjct: 205 AKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIPLFESLDRLEKMLEGQD--YLIGGQ 262 Query: 147 VSAVDLSLAPKLYHLQVAL-GHFKSW--SVPESFPHVHNYMKTLF-SLDSFEKTKTEEKY 202 ++ D+ L + HFK ++ + +P++H +M+ L+ +F+ T ++ Sbjct: 263 LTEADIRLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWMRKLYWGNPAFKDTC-NFEH 321 Query: 203 VISGW 207 + + + Sbjct: 322 IKTHY 326 >4PTS-A nrPDB Length = 348 Score = 53.1 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 51/247 (20%), Positives = 79/247 (31%), Gaps = 56/247 (22%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLINL----SDKPQWFLDISPQGKVPVLKI--------- 65 CP++ R L+ L + + L DK W D+ P G PVL I Sbjct: 55 ACPWANRTLIVRRLLGLE-NVLSLGLCGPTHDKNSWTFDLDPGGVDPVLGIPRLKDAYEK 113 Query: 66 ------DDKWVTDSDVIV--GILEEKYP----------------DPPLKTP----AEFAS 97 V I ++ +P P P AE Sbjct: 114 RFPGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAPQLYPEHLRAEIDE 173 Query: 98 VGSNIFGTFGT------FLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVD 151 V I+ F S+D+ D + L +L+ L L ++ G+ ++ D Sbjct: 174 VSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQ--RYLVGDTITEAD 231 Query: 152 LSLAPKLYHLQVAL-GHFK-SWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW-- 207 + L L GHFK + S P + Y + LF F T T+ + + Sbjct: 232 VRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGFGDT-TDFTQIKQHYYI 290 Query: 208 -APKVNP 213 +NP Sbjct: 291 VHSDINP 297 >1B48-A nrPDB Length = 221 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 32/184 (17%), Positives = 65/184 (35%), Gaps = 20/184 (10%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISP--QGKVPVLKIDDKWVTDSDVIVGILEEK 83 L + ++ + ++ + G+VP+++ID +T + I+ L K Sbjct: 18 IRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEIDGMMLTQTRAILSYLAAK 77 Query: 84 YPDPPLKTPAEFASVGSNIFGT--------FGTFLKSKDSNDGSE----HALLVELEALE 131 Y + K E + GT F K+ + + A E Sbjct: 78 Y-NLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESYDLILSRAKTRYFPVFE 136 Query: 132 NHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLD 191 LK H F+ G ++S D+ L + ++ S V FP + + + ++ Sbjct: 137 KILKDHGEAFLVGNQLSWADIQLLEAILMVEEL-----SAPVLSDFPLLQAFKTRISNIP 191 Query: 192 SFEK 195 + +K Sbjct: 192 TIKK 195 >2VCV-A nrPDB Length = 222 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 69/189 (36%), Gaps = 30/189 (15%) Query: 26 ALLTLEEKSLTYKIHLI-------NLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVG 78 L + ++ I L + +VP+++ID + + I+ Sbjct: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQ-----QVPMVEIDGMKLVQTRAILN 73 Query: 79 ILEEKYPDPPLKTPAEFASVGS------NIFGTFGTFLKSKDSNDGSEHALLVE------ 126 + KY + K E A + ++ + ++ AL+ E Sbjct: 74 YIASKY-NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRY 132 Query: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKT 186 A E L+SH ++ G ++S D+SL LY+++ S+ +FP + Sbjct: 133 FPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-----DSSLISNFPLLKALKTR 187 Query: 187 LFSLDSFEK 195 + +L + +K Sbjct: 188 ISNLPTVKK 196 >1GUL-A nrPDB Length = 222 Score = 52.3 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 30/199 (15%), Positives = 72/199 (36%), Gaps = 27/199 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISP--QGKVPVLKIDDKWVTDSDVIVGILEEK 83 L + + + ++ D + +VP+++ID + + I+ + +K Sbjct: 19 VRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADK 78 Query: 84 YPDPPLKTPAEFASVGSNIFGTFGTFL------------KSKDSNDGSEHALLVELEALE 131 + + K E + + GT + K+ + ++ A++ E Sbjct: 79 H-NLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFE 137 Query: 132 NHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLD 191 L+ H F+ G ++S D+ L + L+ K ++ +FP + Y L ++ Sbjct: 138 KILRGHGQSFLVGNQLSLADVILLQTILALEE-----KIPNILSAFPFLQEYTVKLSNIP 192 Query: 192 SFE-------KTKTEEKYV 203 + + K K + Sbjct: 193 TIKRFLEPGSKKKPPPDEI 211 >6GCB-A nrPDB Length = 325 Score = 51.5 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 7/110 (6%) Query: 109 FLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVAL-GH 167 F ++ + + + L L+ LE L D ++ G++++ D+ L + A GH Sbjct: 197 FATTQQAYEAAVIPLFESLDRLEKILTGKD--YLVGDQLTEADVRLFVTIIRFDPAYVGH 254 Query: 168 FKSW--SVPESFPHVHNYMKTLF-SLDSFEKTKTEEKYVISGWAPK-VNP 213 FK ++ + +P +H +++ L+ + +F +T + S +A K VNP Sbjct: 255 FKCNLRTIRDGYPAIHLWLRKLYWNNSAFSETCKFDHIKASYYAQKNVNP 304 >5AN1-A nrPDB Length = 219 Score = 50.7 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 71/196 (36%), Gaps = 22/196 (11%) Query: 23 SQRALLTLEEKSLTYKIHLINLSD-----KPQWFLDISPQG----KVPVLKIDDKWVTDS 73 Q L L ++ + D K +W G +P D +T S Sbjct: 14 CQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYYIDGDVKITQS 73 Query: 74 DVIVGILEEKY------PDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 I+ L K+ P+ ++T + F + + D +L +L Sbjct: 74 KAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQKDAYTASLPAKL 133 Query: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 + L S P+ AG++++ +D LA +++ ++L + F ++ + K Sbjct: 134 RQYSDFLGS--RPWFAGDKLTYIDF-LAYEIFDQHLSLDRTC----LDGFKNLQAFQKRF 186 Query: 188 FSLDSFEKTKTEEKYV 203 L++ +K K++ Sbjct: 187 EDLEAIKKYMASPKFL 202 >2VCT-A nrPDB Length = 222 Score = 49.6 bits (117), Expect = 9e-07, Method: Composition-based stats. Identities = 34/187 (18%), Positives = 67/187 (35%), Gaps = 26/187 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG-----KVPVLKIDDKWVTDSDVIVGIL 80 L + ++ + + G +VP+++ID + + I+ + Sbjct: 19 IRWLLAAAGVEFE---EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 Query: 81 EEKYPDPPLKTPAEFASVGSNIFG--------TFGTFLKSKDSNDGS----EHALLVELE 128 KY + K E A + I G F + ++ + E Sbjct: 76 ASKY-NLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAKLALIQEKTKNRYFP 134 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 A E LKSH ++ G ++S D+ L LY+++ S+ SFP + + Sbjct: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-----DSSLISSFPLLKALKTRIS 189 Query: 189 SLDSFEK 195 +L + +K Sbjct: 190 NLPTVKK 196 >3KXO-A nrPDB Length = 202 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 26/173 (15%), Positives = 61/173 (35%), Gaps = 22/173 (12%) Query: 35 LTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEK-----YPDPPL 89 + Y+ H I +D P+ + P GK+P+L++D + S I L + + Sbjct: 30 IQYEDHRIEQADWPEIKSTL-PFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQ 88 Query: 90 KTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVE-----LEALENHLKSHDGPFIAG 144 + F K +D + + LL ++ L+ +L + ++ G Sbjct: 89 CHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGRE--WLIG 146 Query: 145 ERVSAVDLSLAPKLYHLQVALGHFKSW--SVPESFPHVHNYMKTLFSLDSFEK 195 V+ D ++ + + ++ P + K + ++ + Sbjct: 147 NSVTWADFY-------WEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVAN 192 >4LMW-A nrPDB Length = 251 Score = 48.8 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 53/248 (21%), Positives = 81/248 (32%), Gaps = 55/248 (22%) Query: 1 MALE--ICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDI-SPQ 57 M+LE I P + P + + L K L Y+ + D I +P Sbjct: 1 MSLEPIIFYDIPANEPRQMAWGPNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPA 60 Query: 58 G----------KVPVLKI--DDKWVTDSDVIVGILEEKYPDPPLKTPAE----------- 94 +PV++ V DSD I LE YPD P P Sbjct: 61 TEKKPDGRDHYTLPVIQDPNTKAVVADSDAIAKYLESTYPDTPRLFPEGTRAFQHAFYQL 120 Query: 95 ---------FASVGSNIFGTFGT------------FLKSKDSNDGSE---HALLVELEAL 130 F V + ++ L K GSE +AL L + Sbjct: 121 ARPSVLMPIFNIVVARVWKLLRPRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARI 180 Query: 131 ENHLK---SHDGPFIAGERVSAVDLSLAPKLYHLQV-ALGHFKSWSVPESFPHVHNYMKT 186 ++ L+ + + G+RV+ DL LA L+V A + W S H + K Sbjct: 181 KSSLEANGAGKDLLLMGDRVTFADLQLASLFIWLRVSAGEESEDWKRFLSL-HEGKWAKF 239 Query: 187 LFSLDSFE 194 + ++E Sbjct: 240 MQQFAAYE 247 >3I6A-A nrPDB Length = 222 Score = 48.8 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 69/187 (36%), Gaps = 26/187 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG-----KVPVLKIDDKWVTDSDVIVGIL 80 L + ++ + + G +VP+++ID + + I+ + Sbjct: 19 TRWLLAAAGVEFE---EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 Query: 81 EEKYPDPPLKTPAEFASVGSNI-----FGTFGTFLKSKDSNDG-SEHALLVE------LE 128 KY + K E A + I G L + ++ AL+ E Sbjct: 76 ASKY-NLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKDAKLALIKEKIKNRYFP 134 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 A E LKSH ++ G ++S D+ L LY+++ S+ SFP + + Sbjct: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-----DSSLISSFPLLKALKTRIS 189 Query: 189 SLDSFEK 195 +L + +K Sbjct: 190 NLPTVKK 196 >6GC9-A nrPDB Length = 327 Score = 48.8 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 10/114 (8%) Query: 107 GTFLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVAL- 165 F S+ + + + L L+ LE L D ++ G++++ D+ L + Sbjct: 196 SGFATSQKAYEAAVVPLFESLDRLEKILTGKD--YLVGDQLTEADIRLFVTIVRFDPVYV 253 Query: 166 GHFKSW--SVPESFPHVHNYMKTLF-SLDSFEKTKTEEKYVISGW---APKVNP 213 GHFK ++ + +P + +M+ L+ + +F T +++ + + P++NP Sbjct: 254 GHFKCNIRTIRDGYPAIDLWMRKLYWNNSAFSSTC-NFEHIKTHYYWSHPQINP 306 >2FHE-A nrPDB Length = 216 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 71/199 (35%), Gaps = 22/199 (11%) Query: 24 QRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG----KVPVLKIDDKWVTDSDVIVGI 79 Q L LE Y+ + D +WF G +P D +T S I+ Sbjct: 14 QPVRLLLEYLGEKYEEQIYERDDGEKWFSKKFELGLDLPNLPYYIDDKCKLTQSLAILRY 73 Query: 80 LEEKY-------PDPPLKTPAEFASVG-SNIFGTFGTFLKSKDSNDGSEHALLVELEALE 131 + +K+ + + E A+V K + +G L ++ Sbjct: 74 IADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFEQLKEGYLKDLPTTMKMWS 133 Query: 132 NHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLD 191 + L P++ G VS VD + L ++ H + FP++ +M + +L Sbjct: 134 DFL--GKNPYLRGTSVSHVDFMVYEALDAIRYLEPH-----CLDHFPNLQQFMSRIEALP 186 Query: 192 SFEKTKTEEKYV---ISGW 207 S + +++ ++GW Sbjct: 187 SIKAYMESNRFIKWPLNGW 205 >1ZL9-A nrPDB Length = 207 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 56/156 (35%), Gaps = 21/156 (13%) Query: 55 SPQGKVPVLKIDDKWVTDSDVIVGILE-----------EKYPDPPLKTPAEFASVGSNIF 103 +P G++P L++D K + S I L E+ L + S + + Sbjct: 48 APFGQLPFLEVDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPY 107 Query: 104 GTFGTFLKSKDSNDGSEHALLVELE----ALENHLKSHDGPFIAGERVSAVDLSLAPKLY 159 D + L E L N LK+ F+ G+ ++ +DL++A Sbjct: 108 FYAVMGFGPGDVETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSA 167 Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEK 195 L G F FP + + + + ++ +K Sbjct: 168 DLIAKGGDF------SKFPELKAHAEKIQAIPQIKK 197 >1PL2-A nrPDB Length = 222 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 33/187 (17%), Positives = 66/187 (35%), Gaps = 26/187 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG-----KVPVLKIDDKWVTDSDVIVGIL 80 L + ++ + + G +VP+++ID + I+ + Sbjct: 19 TRWLLAAAGVEFE---EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQERAILNYI 75 Query: 81 EEKYPDPPLKTPAEFASVGS------NIFGTFGTFLKSKDSNDGSEHALLVE------LE 128 KY + K E A + ++ ++ AL+ E Sbjct: 76 ASKY-NLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFP 134 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 A E LKSH ++ G ++S D+ L LY+++ S+ SFP + + Sbjct: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-----DSSLISSFPLLKALKTRIS 189 Query: 189 SLDSFEK 195 +L + +K Sbjct: 190 NLPTVKK 196 >1EV4-A nrPDB Length = 221 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 33/187 (17%), Positives = 61/187 (32%), Gaps = 26/187 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG-----KVPVLKIDDKWVTDSDVIVGIL 80 L + + P+ + G +VP+++ID + + I+ + Sbjct: 18 IRFLLAAAGVEFD---EKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYI 74 Query: 81 EEKYPDPPLKTPAEFA----------SVGSNIFGTFGTFLKSKDSNDGSEHALLVE--LE 128 KY D K E A + I K++ L Sbjct: 75 ATKY-DLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKTALAKDRTKNRYLP 133 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 A E LKSH ++ G +++ VD+ + S+ SFP + + + Sbjct: 134 AFEKVLKSHGQDYLVGNKLTRVDIH-----LLELLLYVEEFDASLLTSFPLLKAFKSRIS 188 Query: 189 SLDSFEK 195 SL + +K Sbjct: 189 SLPNVKK 195 >2AAW-A nrPDB Length = 222 Score = 47.3 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 40/111 (36%), Gaps = 12/111 (10%) Query: 56 PQGKVPVLKIDDKWVTDSDVIVGILEEKY-----PDPPLKTPAEFASVGSNIFGTF-GTF 109 P +VP+L+I D + S IV L +KY + +I F T Sbjct: 66 PFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTN 125 Query: 110 LKSKDSNDGSEHALLVELEALENHLK------SHDGPFIAGERVSAVDLSL 154 L ++ L E LK ++D + G ++ DL++ Sbjct: 126 LFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAV 176 >4G0L-A nrPDB Length = 328 Score = 47.3 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 36/247 (14%), Positives = 79/247 (31%), Gaps = 55/247 (22%) Query: 19 DCPFSQRALLTLEEKS----LTYKIHLINLSDKPQWFLDISPQGK--------------- 59 CP++ R L+ + K ++ + + + F D P Sbjct: 62 ACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNEFLYQLYL 121 Query: 60 -----------VPVL---KIDDKWVTDSDVIVGILEEKYPDPPLK----TPAEFASVGSN 101 VPVL K +S I+ + + K P + Sbjct: 122 HADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDE 181 Query: 102 IFGTFGT----------FLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVD 151 + G F S+++ D + + L LE L H ++ G +++ D Sbjct: 182 LNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQH--RYLTGNQLTEAD 239 Query: 152 LSLAPKLYHLQVAL-GHFKSWSVP-ESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW-- 207 + L L HFK + +++ +++ ++ + +T + ++ + + Sbjct: 240 IRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFD-HIRNHYFR 298 Query: 208 -APKVNP 213 +NP Sbjct: 299 SHKTINP 305 >5Y9Z-A nrPDB Length = 199 Score = 47.3 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 15/130 (11%) Query: 35 LTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAE 94 + Y+ H I +D P+ + P GK+PVL+++ + S I L K D KT E Sbjct: 27 IKYEDHRIEQADWPKIKPTL-PFGKIPVLEVEGLTLHQSLAIARYL-TKNTDLAGKTELE 84 Query: 95 FASVG------SNIFGTFGTFLKSKDSNDGSEHALLVE-----LEALENHLKSHDGPFIA 143 V + F +++D + + + LL L+ L+ +L D + Sbjct: 85 QCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYL--GDKEWFI 142 Query: 144 GERVSAVDLS 153 G V+ D Sbjct: 143 GNYVTWADFY 152 >2HNL-A nrPDB Length = 225 Score = 46.5 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 35/179 (19%), Positives = 66/179 (36%), Gaps = 19/179 (10%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYP 85 L +++Y+ + I D+ ++ +P G VP+L + + +S I +L ++ Sbjct: 42 IRLLFALANVSYEDNRI-TRDEWKYLKPRTPFGHVPMLNVSGNVLGESHAIELLLGGRFG 100 Query: 86 DPPL--KTPAEFASVGSNIFGTFGTFLK-SKDSNDGSEHALLVELE---------ALENH 133 A+ +V NI F + + + N + L L E Sbjct: 101 LLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTKKAELFRNLSESDVMPFLGRYEKF 160 Query: 134 LKSHDGPFIAGERVSAVDLSLAPKLYHL--QVALGHFKSW----SVPESFPHVHNYMKT 186 LK I G +VS DL++ L L +V L + + P + ++K Sbjct: 161 LKESTTGHIVGNKVSVADLTVFNMLMTLDDEVKLEEYPQLASFVNKIGQMPGIKEWIKK 219 >5LCZ-A nrPDB Length = 222 Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 61/187 (32%), Gaps = 26/187 (13%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQG-----KVPVLKIDDKWVTDSDVIVGIL 80 L + ++ + + G +VP+++ID + + I+ + Sbjct: 19 TRWLLAAAGVEFE---EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 Query: 81 EEKYPDPPLKTPAEFA----------SVGSNIFGTFGTFLKSKDSNDGSEHALLVE--LE 128 KY + K E A + I +++ L Sbjct: 76 ASKY-NLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAKTALAKDRTKNRYLP 134 Query: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 A E LKSH ++ G R++ VD+ + S+ SFP + + + Sbjct: 135 AFEKVLKSHGQDYLVGNRLTRVDIH-----LLELLLYVEEFDASLLTSFPLLKAFKSRIS 189 Query: 189 SLDSFEK 195 SL + +K Sbjct: 190 SLPNVKK 196 >1G7O-A nrPDB Length = 215 Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 34/182 (18%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVL-KIDDKWVTDSDVI 76 CP+ +A + K++ ++H + L+D + + Q +VP+L K D +++ +S I Sbjct: 7 DHCPYCLKARMIFGLKNIPVELH-VLLNDDAETPTRMVGQKQVPILQKDDSRYMPESMDI 65 Query: 77 VGILEEKYPDPPL---KTPA---------------EFASVGSNIFGTFGT------FLKS 112 V +++ P L ++PA + F F T F+ Sbjct: 66 VHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFSTPAARKYFVDK 125 Query: 113 KDSNDGSEHALLVE----LEALENHLKSHD----GPFIAGERVSAVDLSLAPKLYHLQVA 164 K+++ G+ LL ++ + + L++ D P +S D+ L P L +L + Sbjct: 126 KEASAGNFADLLAHSDGLIKNISDDLRALDKLIVKPNAVNGELSEDDIQLFPLLRNLTLV 185 Query: 165 LG 166 G Sbjct: 186 AG 187 >4USS-A nrPDB Length = 325 Score = 45.7 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 8/110 (7%) Query: 109 FLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALG-H 167 F + + + + L L+ E L +I G +S D+ L L H Sbjct: 196 FARKQGPYEEAAIQLYEALDKCEEILGRQ--RYICGNTLSEADIKLFVTLIRFDEVYAVH 253 Query: 168 FK-SWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGW---APKVNP 213 FK + + +P++ NY K +F + T +++ + P VNP Sbjct: 254 FKCNKKLLRDYPNMFNYTKDIFQIPGMSSTV-NMQHIKRHYYGSHPTVNP 302 >5F8B-A nrPDB Length = 244 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 29/184 (15%), Positives = 61/184 (33%), Gaps = 26/184 (14%) Query: 29 TLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKW-VTDSDVIVGILEEKYPDP 87 + L I + L IS GKVP + D + + + I + + Sbjct: 22 VAKANGLDLDIRETP---RTPDHLSISKLGKVPAFQGADSFKLFECMAIALYITSQNEQT 78 Query: 88 PL--KTPAEFASVGS---------------NIFGTFGTFLKSKDSNDGSEHALLVELEAL 130 L K E+A + + G +D + + ++ + Sbjct: 79 TLLGKDKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGVIPYDRDQVEFFANMTQRSVDVV 138 Query: 131 ENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL 190 E +L D F+ G+++S DL A ++ + F + + P+V + + + Sbjct: 139 EEYL--QDRTFLVGDQLSLADLFCA---GNISLGFQFFYGKAWRQQNPNVSRWYEMVCHQ 193 Query: 191 DSFE 194 + Sbjct: 194 PIYA 197 >5FWG-A nrPDB Length = 217 Score = 43.0 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 63/199 (31%), Gaps = 29/199 (14%) Query: 24 QRALLTLEEKSLTYKIHLINLSDKP-----QWFLDISPQG----KVPVLKIDDKWVTDSD 74 L LE +Y+ + D P QW + G +P L + +T S+ Sbjct: 14 HPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSN 73 Query: 75 VIVGILEEKY------PDPPLKTPAEFASVGSNIFGTFGTFLKS--KDSNDGSEHALLVE 126 I+ L K+ + ++ V N + + + Sbjct: 74 AIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEK 133 Query: 127 LEALENHLKSHDGPFIAGERVSAVD---LSLAPKLYHLQV----ALGHFKSWSVP-ESFP 178 ++ L P+ AG++V+ VD + + + + A + K + E Sbjct: 134 MKLYSEFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLK 191 Query: 179 HVHNYMK--TLFSLDSFEK 195 + YMK S F K Sbjct: 192 KISAYMKSSRYLSTPIFSK 210 >1TU7-A nrPDB Length = 208 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 59/176 (33%), Gaps = 18/176 (10%) Query: 35 LTYKIHLINLSDKPQWFLDISPQ---GKVPVLKIDDKWVTDSDVIVGILEEKYP-----D 86 + I I+ F I Q G++P L D+ + S I+ L KY + Sbjct: 22 VDQDIKFIDDRIAKDDFSSIKSQFQFGQLPCLYDGDQQIVQSGAILRHLARKYNLNGENE 81 Query: 87 PPLKTPAEFASVGSNIFGTFGTFLK---SKDSNDGSEHALLVELEALENHLKSHD--GPF 141 F ++ + + + + + L EL E L + Sbjct: 82 METTYIDMFCEGVRDLHVKYTRMIYMAYETEKDPYIKSILPGELAKFEKLLATRGNGRNL 141 Query: 142 IAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTK 197 I G+++S D +L +L Q+ H + FP + + + + ++ Sbjct: 142 ILGDKISYADYALFEELDVHQILDPH-----CLDKFPLLKVFHQRMKDRPKLKEYC 192 >1B4P-A nrPDB Length = 217 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 38/217 (17%), Positives = 69/217 (31%), Gaps = 43/217 (19%) Query: 24 QRALLTLEEKSLTYKIHLINLSDKP-----QWFLDISPQG----KVPVLKIDDKWVTDSD 74 L LE +Y+ + D P QW + G +P L + +T S+ Sbjct: 14 HPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSN 73 Query: 75 VIVGILE-------EKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 I+ L E + E ++ + + + + + L L Sbjct: 74 AIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCY---SPDFERKKPEYLEGL 130 Query: 128 ----EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV-------ALGHFKSWSVP-E 175 + L P+ AG +++ VD + L ++ A + K + E Sbjct: 131 PEKMKLYSEFL--GKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNLKDFVARFE 188 Query: 176 SFPHVHNYMK--TLFSLDSFEKTKTEEKYVISGWAPK 210 + +YMK S F K ++ W PK Sbjct: 189 GLKKISDYMKSGRFLSKPIFAK--------MAFWNPK 217 >1GSQ-A nrPDB Length = 202 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 31/185 (16%), Positives = 53/185 (28%), Gaps = 29/185 (15%) Query: 26 ALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYP 85 L + ++ ++D P + +PVL ID ++ S I L ++ Sbjct: 17 CRFVLAAHGEEFTDRVVEMADWPNLKATMYS-NAMPVLDIDGTKMSQSMCIARHLAREF- 74 Query: 86 DPPLKTPAEFASVGS------NIFGTFGTF-LKSKDSNDGSEHALLVELEALENHL---- 134 KT E V +IF + + + + + L L Sbjct: 75 GLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQQNYEKSCKRLAPFLEGLL 134 Query: 135 --KSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSW--SVP---------ESFPHVH 181 F G ++ DL L+V L H P P + Sbjct: 135 VSNGGGDGFFVGNSMTLADLHC---YVALEVPLKHTPELLKDCPKIVALRKRVAECPKIA 191 Query: 182 NYMKT 186 Y+K Sbjct: 192 AYLKK 196 >3IR4-A nrPDB Length = 218 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 18 GDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVL-KIDDKWVTDSDVI 76 CPF +A + K++ +++++ D+ I Q VP+L K D +++ +S I Sbjct: 10 DHCPFCVKARMIFGLKNIPVELNVLQNDDEATPTRMIG-QKMVPILQKDDSRYLPESMDI 68 Query: 77 VGILEEKYPDPPL 89 V ++ P L Sbjct: 69 VHYVDNLDGKPLL 81 >2PBJ-A nrPDB Length = 290 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 47/127 (37%), Gaps = 19/127 (14%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLK----IDDKWVTDSDV 75 CPF + L+ +L Y++ +N + + + S KVP+L + + DS V Sbjct: 23 CPFCSKVRAFLDFHALPYQVVEVNPVLRAE--IKFSSYRKVPILVAQEGESSQQLNDSSV 80 Query: 76 IV----------GILEEKYP-DPPLKTPAEFASVGSNIFGTFGTFLKSKDSND--GSEHA 122 I+ LEE P +K + + + L K++ + A Sbjct: 81 IISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGNKYWLMLNEKEAQQVYSGKEA 140 Query: 123 LLVELEA 129 E++ Sbjct: 141 RTEEMKW 147 Score = 27.6 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 8/64 (12%), Positives = 23/64 (35%), Gaps = 6/64 (9%) Query: 136 SHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEK 195 D PF+ G++ + DL+ +Y + + ++ H+ + + + + Sbjct: 232 GKDRPFMGGQKPNLADLA----VYGVLRVMEGLDAFDDLMQHTHIQPWYLRVER--AITE 285 Query: 196 TKTE 199 Sbjct: 286 ASPA 289 >4Q5R-A nrPDB Length = 204 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 19/152 (12%) Query: 56 PQGKVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAE------FASVGSNIFGTFGTF 109 P GK PVL+ID K S I L +++ K E S+ + Sbjct: 48 PFGKTPVLEIDGKQTHQSVAISRYLGKQF-GLSGKDDWENLEIDMIVDTISDFRAAIANY 106 Query: 110 LKSKDSNDGSEHA--LLVE-----LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 D N + L E + + +K++ G ++A +++ D L +L Sbjct: 107 HYDADENSKQKKWDPLKKETIPYYTKKFDEVVKANGG-YLAAGKLTWADFYFVAILDYL- 164 Query: 163 VALGHFKSWSVPESFPHVHNYMKTLFSLDSFE 194 H + + P++ + + L + + Sbjct: 165 ---NHMAKEDLVANQPNLKALREKVLGLPAIK 193 >2DC5-A nrPDB Length = 231 Score = 40.7 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 37/217 (17%), Positives = 65/217 (29%), Gaps = 35/217 (16%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKP-----QWFLDISPQG----KVPVLKIDDKWVTDS 73 + L LE +Y+ + D P QW + G +P L +T S Sbjct: 21 AHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQS 80 Query: 74 DVIVGIL-------EEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVE 126 + I+ L E + E + + + + + L Sbjct: 81 NAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPGYLEQLPG 140 Query: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV-------ALGHFKSWSVP-ESFP 178 + L + P+ AG++++ VD L QV A + K + E Sbjct: 141 MMRLYSEFLG-KRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPNLKDFIARFEGLK 199 Query: 179 HVHNYMK--TLFSLDSFEKTKTEEKYVISGWAPKVNP 213 + +YMK F K ++ W P Sbjct: 200 KISDYMKTSRFLPRPMFTK--------MATWGSNSGP 228 >1HNA-A nrPDB Length = 217 Score = 40.7 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 67/201 (33%), Gaps = 31/201 (15%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKP-----QWFLDISPQG----KVPVLKIDDKWVTDS 73 + L LE +Y+ + D P QW + G +P L +T S Sbjct: 13 AHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQS 72 Query: 74 DVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDS----NDGSEHALLVELEA 129 + I+ + K+ L +E + +I + + + + E L+A Sbjct: 73 NAILRYIARKH---NLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQA 129 Query: 130 LENHLK-----SHDGPFIAGERVSAVDLSLAPKLYHLQV-------ALGHFKSW-SVPES 176 L LK P+ G++++ VD L QV A + K + S E Sbjct: 130 LPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEG 189 Query: 177 FPHVHNYMK--TLFSLDSFEK 195 + YMK F K Sbjct: 190 LEKISAYMKSSRFLPRPVFTK 210 >1FHE-A nrPDB Length = 217 Score = 40.7 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 35/178 (19%), Positives = 69/178 (38%), Gaps = 22/178 (12%) Query: 46 DKPQWFLDISPQG----KVPVLKIDDKWVTDSDVIVGILEEKY-------PDPPLKTPAE 94 D+ +W + G +P D +T S I+ + +K+ + + E Sbjct: 36 DREKWMSEKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIE 95 Query: 95 FASVGSNI-FGTFGTFLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLS 153 A++ I FG K ++ + L L+ + L D ++ G VS VD Sbjct: 96 GAAMDLRIGFGRVCYNPKFEEVKEEYVKELPKTLKMWSDFL--GDRHYLTGSSVSHVDFM 153 Query: 154 LAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLD---SFEKTKTEEKYVISGWA 208 L L ++ H + FP + + + +L ++ ++K K+ ++GWA Sbjct: 154 LYETLDSIRYLAPH-----CLDEFPKLKEFKSRIEALPKIKAYMESKRFIKWPLNGWA 206 >5LKB-A nrPDB Length = 378 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 37/238 (15%), Positives = 79/238 (33%), Gaps = 52/238 (21%) Query: 23 SQRALLTLEEKSLTYKIHLI-NLSDKPQWFLDISPQGKVPVL---KIDDKWVTDSDVIV- 77 SQR + Y I +L K S + VPVL + +S I+ Sbjct: 123 SQR-FMVDATNEPHYGYKRISDLYYKSD--PQYSARFTVPVLWDLETQTIVNNESSEIIR 179 Query: 78 --------GILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSK----------DSNDGS 119 +++ + L PA+ + + + + + + Sbjct: 180 ILNSSAFDEFVDDDHKKTDLV-PAQLKTQIDDFNSWVYDSINNGVYKTGFAEKAEVYESE 238 Query: 120 EHALLVELEALENHLKSHDGP-----------------FIAGERVSAVDLSLAPKLYHLQ 162 + + L+ +E L F G++++ D+ L + Sbjct: 239 VNNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFD 298 Query: 163 VAL-GHFKSW--SVPESFPHVHNYMKTLF-SLDSFEKTKTEEKYVISGWA---PKVNP 213 HFK S+ +P +H +++ L+ + D+F T T+ ++ + ++NP Sbjct: 299 PVYVQHFKCNFTSIRAGYPFIHLWVRNLYWNYDAFRYT-TDFDHIKLHYTRSHTRINP 355 Score = 27.6 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 11/18 (61%) Query: 19 DCPFSQRALLTLEEKSLT 36 CP++ R L+T K LT Sbjct: 45 ACPWAHRTLITRALKGLT 62 >1XWK-A nrPDB Length = 218 Score = 38.8 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 34/200 (17%), Positives = 64/200 (32%), Gaps = 29/200 (14%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKP-----QWFLDISPQG----KVPVLKIDDKWVTDS 73 + L LE +Y+ + D P QW + G +P L +T S Sbjct: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 Query: 74 DVIVGILE-------EKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE-HALLV 125 + I+ + E + E ++ +++ + + L Sbjct: 74 NAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPE 133 Query: 126 ELEALENHLKSHDGPFIAGERVSAVDLSL--APKLYHLQV-----ALGHFKSW-SVPESF 177 +L+ L P+ AG +++ VD + L+ + A + K + S E Sbjct: 134 KLKLYSEFL--GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGL 191 Query: 178 PHVHNYMK--TLFSLDSFEK 195 + YMK F K Sbjct: 192 EKISAYMKSSRFLPRPVFSK 211 >4LMV-A nrPDB Length = 252 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 35/99 (35%), Gaps = 16/99 (16%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDI--SPQGK---------VPVLKI-DD 67 P + + L K + YK + D + P GK VPV+ + Sbjct: 21 SPNTWKIRYALNIKGIKYKTEWVEYPDIEDVVKKLGGKPTGKKPDGRDHYTVPVIYDPNT 80 Query: 68 KWVTDS-DVIVGILEEKYPDPPLKTPAE---FASVGSNI 102 K V + I L++ YPD P PA F + + Sbjct: 81 KTVVEDGIKIAKYLDDAYPDTPRLFPAGTDAFQAAFDDF 119 >4LA1-A nrPDB Length = 602 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 28/64 (43%), Gaps = 4/64 (6%) Query: 20 CPFSQRALLTLEEKSLTYKIHLIN-LSDKP---QWFLDISPQGKVPVLKIDDKWVTDSDV 75 CPF ++ L E + + ++ LS+ + + S VP + + K++ DS Sbjct: 34 CPFCKKLKDVLAEAKIKHATIELDQLSNGSVIQKALSNFSKIETVPQMFVRGKFIGDSKA 93 Query: 76 IVGI 79 ++ Sbjct: 94 VLNY 97 >4GTU-A nrPDB Length = 217 Score = 38.0 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 62/185 (33%), Gaps = 22/185 (11%) Query: 23 SQRALLTLEEKSLTYKIHLINLSDKP-----QWFLDISPQG----KVPVLKIDDKWVTDS 73 + L LE +Y+ + D P QW + G +P L +T S Sbjct: 13 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 72 Query: 74 DVIVGILEEKY-----PDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELE 128 + I+ + K+ + + ++ S D + + L EL Sbjct: 73 NAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD-FEKLKPEYLEELP 131 Query: 129 ALENHLKS--HDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKT 186 + H P+ G++++ VD L L + ++FP++ +++ Sbjct: 132 TMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLD-----LHRIFEPNCLDAFPNLKDFISR 186 Query: 187 LFSLD 191 L+ Sbjct: 187 FEGLE 191 >1M0U-A nrPDB Length = 249 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 60/171 (35%), Gaps = 18/171 (10%) Query: 36 TYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEK--YPDPPLKTPA 93 Y+ + D+ P G++PVL++D K V S + L + Sbjct: 74 EYEDVRV-TRDEWPALKPTMPMGQMPVLEVDGKRVHQSISMARFLAKTVGLCGATPWEDL 132 Query: 94 EFASVGSNIFG-TFGTFLKSKDSNDGSEHALLVELEA---------LENHLKSHDGPFIA 143 + V I + S + D + LV L A LE +K +DG Sbjct: 133 QIDIVVDTINDFRLKIAVVSYEPEDEIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLAL 192 Query: 144 GERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFE 194 G +++ D+ + + + + E +P + + + +L+ + Sbjct: 193 G-KLTWADVY----FAGITDYMNYMVKRDLLEPYPALRGVVDAVNALEPIK 238 >4BVY-B nrPDB Length = 186 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 51/129 (39%), Gaps = 9/129 (6%) Query: 59 KVPVLKIDDKW-VTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSND 117 ++PVL+ +D +T I L ++ L + I + + ++ Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLL---GSTAEEKAIVQQWLEYRVTQVDGH 97 Query: 118 GSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV---ALGHFKSWSVP 174 S++ + L+ L ++L+ D ++ G + D+ L L+ V K +V Sbjct: 98 SSKNDIHTLLKDLNSYLE--DKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVS 155 Query: 175 ESFPHVHNY 183 F H+ +Y Sbjct: 156 RWFSHIQHY 164 >2WRT-A nrPDB Length = 218 Score = 36.1 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 37/164 (22%), Positives = 55/164 (33%), Gaps = 28/164 (17%) Query: 46 DKPQWFLDISPQG----KVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGS- 100 D+ +W D G +P D +T S I+ + +K+ TP E A + Sbjct: 37 DREKWLGDKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADKH-GMLGSTPEERARISMI 95 Query: 101 --------NIFGTFGTFLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDL 152 F K ++ L L+ N L D ++ G VS VD Sbjct: 96 EGAAMDLRMGFVRVCYNPKFEEVKGDYLKELPTTLKMWSNFL--GDRHYLTGSSVSHVDF 153 Query: 153 S----------LAPKLYHLQVALGHFKSWSVPESFPHVHNYMKT 186 LAP+ L FKS E P + YM++ Sbjct: 154 MVYEALDCIRYLAPQCLEDFPKLKEFKSRI--EDLPKIKAYMES 195 >3GRX-A nrPDB Length = 82 Score = 35.0 bits (79), Expect = 0.024, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 20 CPFSQRALLTLEEKSLTYKIHLIN-LSDKPQWFLDISPQGKVPVLKIDDKWV 70 CP+S RA L K ++++ I+ + K + + S + VP + ID + + Sbjct: 11 CPYSHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFIDAQHI 62 >2KLX-A nrPDB Length = 89 Score = 34.6 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD 67 +CP+ +RA L++K + Y + S + + + + P + I D Sbjct: 15 NCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFPQIFIGD 63 >1NM3-A nrPDB Length = 241 Score = 33.4 bits (75), Expect = 0.074, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 30/78 (38%), Gaps = 9/78 (11%) Query: 2 ALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVP 61 ++ I K CPF +A L +K L+++ ++ +S + VP Sbjct: 171 SISIFTKPG---------CPFCAKAKQLLHDKGLSFEEIILGHDATIVSVRAVSGRTTVP 221 Query: 62 VLKIDDKWVTDSDVIVGI 79 + I K + SD + Sbjct: 222 QVFIGGKHIGGSDDLEKY 239 >3GTU-B nrPDB Length = 224 Score = 33.4 bits (75), Expect = 0.074, Method: Composition-based stats. Identities = 32/194 (16%), Positives = 57/194 (29%), Gaps = 20/194 (10%) Query: 23 SQRALLTLEEKSLTYKIHLINLS-----DKPQWFLDISP----QGKVPVLKIDDKWVTDS 73 + L LE +Y+ D+ QW +P L +T S Sbjct: 17 AHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQS 76 Query: 74 DVIVGILEEKY----PDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELEA 129 + I+ + K+ K + F T L ++ + L EL Sbjct: 77 NAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPG 136 Query: 130 LENHLKSHDGPF--IAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 G F AGE+++ VD L + FP++ +M Sbjct: 137 QLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQ-----NRIFDPKCLDEFPNLKAFMCRF 191 Query: 188 FSLDSFEKTKTEEK 201 +L+ ++ Sbjct: 192 EALEKIAAYLQSDQ 205 >3QMX-A nrPDB Length = 99 Score = 33.0 bits (74), Expect = 0.090, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 2/53 (3%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGK--VPVLKIDDKWV 70 CPF RAL L+ K + ++ + I+ ++ + + GK +P + IDD+ + Sbjct: 26 CPFCMRALALLKRKGVEFQEYCIDGDNEAREAMAARANGKRSLPQIFIDDQHI 78 >1GSU-A nrPDB Length = 219 Score = 31.9 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 54/143 (37%), Gaps = 19/143 (13%) Query: 59 KVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVG------SNIFGTFGTFLKS 112 +P L D +T S+ I+ + K+ + +T E V ++ F S Sbjct: 58 NLPYLIDGDVKLTQSNAILRYIARKH-NMCGETEVEKQRVDVLENHLMDLRMAFARLCYS 116 Query: 113 KDSNDGSEHALLVE----LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHF 168 D + + A L + L L L S + G++++ VD L ++ + Sbjct: 117 PD-FEKLKPAYLEQLPGKLRQLSRFLGSRS--WFVGDKLTFVDFLAYDVLDQQRMFVP-- 171 Query: 169 KSWSVPESFPHVHNYMKTLFSLD 191 PE ++ +++ +L+ Sbjct: 172 ---DCPELQGNLSQFLQRFEALE 191 >1Z7R-A nrPDB Length = 117 Score = 31.1 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 36/88 (40%), Gaps = 12/88 (13%) Query: 20 CPFSQRALLTLEEKSLTYKIHLIN-LSDKPQWFLDIS---PQGKVPVLKIDDKWV--TDS 73 C + R L + +YK+ ++ LSD Q ++ +G VP + I K + D+ Sbjct: 31 CGYCNRVKQLLTQVGASYKVVELDELSDGSQLQSALAHWTGRGTVPNVFIGGKQIGGCDT 90 Query: 74 DVIVGILEEKYPDPPLKTPAEFASVGSN 101 V EK+ L + A+ + Sbjct: 91 VV------EKHQRNELLPLLQDAAATAK 112 >5W1J-A nrPDB Length = 584 Score = 30.3 bits (67), Expect = 0.68, Method: Composition-based stats. Identities = 6/55 (10%), Positives = 21/55 (38%), Gaps = 4/55 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLD----ISPQGKVPVLKIDDKWV 70 CP+ ++ + + + ++L + I+ + VP + +++ Sbjct: 25 CPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFI 79 >3UIW-A nrPDB Length = 154 Score = 29.9 bits (66), Expect = 0.87, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 23/55 (41%), Gaps = 4/55 (7%) Query: 20 CPFSQRALLTLEEKSLTYKIHLI----NLSDKPQWFLDISPQGKVPVLKIDDKWV 70 CP+ + A E TYK+ + + + +++ VP + I+ + + Sbjct: 57 CPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCI 111 >5CAX-A nrPDB Length = 101 Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 7/58 (12%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 17 LGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQ------WFLDISPQGKVPVLKIDDK 68 L C + ++ L + + ++ ++L ++ + +P P ++D+ Sbjct: 27 LSTCVWCKKTKKLLTDLGVDFEYVFVDLLEEEEKSNAIKQVSRFNPSVSFPTTILNDE 84 >4ES6-A nrPDB Length = 254 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 77 VGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELEALENHLKS 136 + L+ +P PP +T + + I +G + + D SE L+ L A ++ L+ Sbjct: 74 LERLDRYWPQPPQQTWCSVGAATAAILEAYGLDVTYPEQGDDSE--ALLALPAFQDSLRV 131 Query: 137 HDGPFI 142 HD + Sbjct: 132 HDPKVL 137 >3IC4-A nrPDB Length = 92 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 17 LGDCPFSQRALLTLEEKSLTYKIHLINLSDKP------QWFLDISPQGKVPVLKIDDKWV 70 L CP +R L L+ + + +++ I+ + + IS VPV+ DK V Sbjct: 19 LSTCPHCKRTLEFLKREGVDFEVIWIDKLEGEERKKVIEKVHSISGSYSVPVVVKGDKHV 78 Query: 71 TDSDVIVGILEEKYPD 86 +G EEK + Sbjct: 79 ------LGYNEEKLKE 88 >3C1S-A nrPDB Length = 118 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 26/59 (44%), Gaps = 8/59 (13%) Query: 20 CPFSQRALLTLEEK-SLTYKIHLI----NLSDKPQW---FLDISPQGKVPVLKIDDKWV 70 CP+ AL TL EK + L+ ++ + +I+ Q VP + I+ K + Sbjct: 35 CPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHI 93 >2MZC-A nrPDB Length = 92 Score = 28.4 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQ---WFLDISPQGKVPVLKIDDKWVTDSDVI 76 CP+ RA L K + I+ S P+ + S + P + I V SD + Sbjct: 16 CPYCARAKALLARKGAEFN--EIDASATPELRAEMQERSGRNTFPQIFIGSVHVGGSDDL 73 Query: 77 VGILEEKYPDPPLKT 91 + +E D LKT Sbjct: 74 YALEDEGKLDSLLKT 88 >6JR6-A nrPDB Length = 838 Score = 28.4 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 16/39 (41%), Gaps = 3/39 (7%) Query: 49 QWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEK--YP 85 QW +P +PV + ++ ++EK YP Sbjct: 667 QWITVDAPLNTIPVFVKKGSIIPQ-MPVMQYIDEKKVYP 704 >1H75-A nrPDB Length = 81 Score = 28.0 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 7/49 (14%), Positives = 18/49 (36%) Query: 19 DCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD 67 DC +E + +++ ++ + L ++PV+ D Sbjct: 10 DCVQCHATKRAMENRGFDFEMINVDRVPEAAEALRAQGFRQLPVVIAGD 58 >3OPB-A nrPDB Length = 778 Score = 27.6 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 14/39 (35%) Query: 50 WFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYPDPP 88 S GK+P + + + D I IL Y D Sbjct: 50 QLRQKSESGKMPADLTNSEALKDRQKIEEILTRSYQDHS 88 >5DXT-A nrPDB Length = 962 Score = 27.6 bits (60), Expect = 4.6, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 26/68 (38%) Query: 24 QRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEK 83 Q+ L + + ++ + K + L S Q K+ VL+ K++ EK Sbjct: 99 QKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEK 158 Query: 84 YPDPPLKT 91 YP K Sbjct: 159 YPLSQYKY 166 >2WYO-A nrPDB Length = 562 Score = 26.9 bits (58), Expect = 6.9, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 16/40 (40%) Query: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTE 199 H +A+ +F+S VPE FP + L S Sbjct: 322 HYPIAVAYFRSTYVPEDFPTDATWAARLSLERSSAIKCPS 361 >3PJP-A nrPDB Length = 199 Score = 26.5 bits (57), Expect = 8.5, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 43/134 (32%), Gaps = 14/134 (10%) Query: 49 QWFLDISPQGKVPVLKIDDKWVTD-SDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFG 107 Q +P VL ++ + D +IV L+ K T E G+ Sbjct: 62 QELEKENPLALGKVLVVEGQRYHDLDQIIVEYLQNKIRLLNELTSNEKFKAGTK--KEVV 119 Query: 108 TFLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGH 167 F++ + + L ++ ++ L+ KLY V L H Sbjct: 120 KFIEDYSKVNPKKSVYYFSLNY-----ENPGWFYL------IFKLNAESKLYIWNVKLTH 168 Query: 168 FKSWSVPESFPHVH 181 + V ++P V Sbjct: 169 TGFFLVNYNYPTVI 182 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.142 0.376 Lambda K H 0.267 0.0431 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,515,208 Number of Sequences: 36641 Number of extensions: 339721 Number of successful extensions: 1247 Number of sequences better than 10.0: 154 Number of HSP's better than 10.0 without gapping: 176 Number of HSP's successfully gapped in prelim test: 62 Number of HSP's that attempted gapping in prelim test: 850 Number of HSP's gapped (non-prelim): 258 length of query: 213 length of database: 10,336,785 effective HSP length: 93 effective length of query: 120 effective length of database: 6,929,172 effective search space: 831500640 effective search space used: 831500640 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.5 bits)