BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9FUP0 (391 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2G5W-A nrPDB 813 0.0 2HS8-A nrPDB 618 e-177 5DXY-A nrPDB 561 e-160 2Q3R-A nrPDB 395 e-110 1ICQ-A nrPDB 387 e-108 4JIP-A nrPDB 281 3e-76 3GX9-A nrPDB 279 2e-75 4AEO-A nrPDB 275 3e-74 3WJS-A nrPDB 270 6e-73 4AWT-A nrPDB 270 1e-72 3GKA-A nrPDB 270 1e-72 5EPD-A nrPDB 269 2e-72 4QNW-A nrPDB 252 2e-67 4A3U-A nrPDB 249 2e-66 6GI9-A nrPDB 244 3e-65 5K1Q-A nrPDB 227 7e-60 5V4P-A nrPDB 218 4e-57 4E2D-A nrPDB 214 5e-56 4GBU-A nrPDB 213 2e-55 4TMB-A nrPDB 201 4e-52 4QAI-A nrPDB 197 8e-51 4RNU-A nrPDB 184 7e-47 4RNX-A nrPDB 138 5e-33 3KRZ-A nrPDB 124 6e-29 5OCS-A nrPDB 117 1e-26 5CPN-A nrPDB 115 3e-26 3GR7-A nrPDB 114 9e-26 1Z48-A nrPDB 108 4e-24 1PS9-A nrPDB 107 1e-23 3HF3-A nrPDB 102 3e-22 3L5A-A nrPDB 80 1e-15 3K30-A nrPDB 73 2e-13 2TMD-A nrPDB 70 1e-12 4LT6-A nrPDB 37 0.021 6D8Z-A nrPDB 34 0.11 5GJL-A nrPDB 34 0.13 5G6R-A nrPDB 32 0.53 3GOC-A nrPDB 30 1.3 3ZE8-A nrPDB 28 4.9 5JSK-A nrPDB 28 5.2 5EGJ-A nrPDB 28 5.6 4PEY-A nrPDB 28 6.1 6CI2-A nrPDB 28 6.6 6CI4-A nrPDB 28 6.8 3I6D-A nrPDB 28 8.4 5UPU-A nrPDB 28 9.0 1ECX-A nrPDB 28 9.7 >2G5W-A nrPDB Length = 391 Score = 813 bits (2100), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/391 (100%), Positives = 391/391 (100%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL Sbjct: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP Sbjct: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 Query: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF Sbjct: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 Query: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS Sbjct: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE Sbjct: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG Sbjct: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 Query: 361 ELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 ELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL Sbjct: 361 ELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 >2HS8-A nrPDB Length = 402 Score = 618 bits (1594), Expect = e-177, Method: Compositional matrix adjust. Identities = 294/397 (74%), Positives = 336/397 (84%), Gaps = 7/397 (1%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 M ++ + N LFS YKMG+F+LSHRVVLAPMTRCRALN +P AAL EYY QR T GGFL Sbjct: 7 MASSAQDGNNPLFSPYKMGKFNLSHRVVLAPMTRCRALNNIPQAALGEYYEQRATAGGFL 66 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 I+EGTM+SP SAGFPHVPGI++ EQV WK++V+ VHAKG IFCQLWHVGRASH VYQP Sbjct: 67 ITEGTMISPTSAGFPHVPGIFTKEQVREWKKIVDVVHAKGAVIFCQLWHVGRASHEVYQP 126 Query: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 G +PISST KPIS NRWR+L+PDG+H YPKPRA+ EI +VVEDY SALNAI AGF Sbjct: 127 AGAAPISSTEKPIS-NRWRILMPDGTHGIYPKPRAIGTYEISQVVEDYRRSALNAIEAGF 185 Query: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 DGIEIHGAHGYLIDQFLKDGINDRTD+YGGS+ANRC+F+ QVV+ VVSAIGA +VGVRVS Sbjct: 186 DGIEIHGAHGYLIDQFLKDGINDRTDEYGGSLANRCKFITQVVQAVVSAIGADRVGVRVS 245 Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 PAIDHLDA DS+PLSLGLAVV LNK+Q +GSKLAYLHVTQPRY AYGQTE+GR GS+E Sbjct: 246 PAIDHLDAMDSNPLSLGLAVVERLNKIQLHSGSKLAYLHVTQPRYVAYGQTEAGRLGSEE 305 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 EEA+LM++LR AY GTF+ SGG+ +ELG++AV QGDADLVSYGRLFI+NPDLV R K++ Sbjct: 306 EEARLMRTLRNAYQGTFICSGGYTRELGIEAVAQGDADLVSYGRLFISNPDLVMRIKLNA 365 Query: 361 ELNKYNRKTFYTQDPVVGYTDYPFL------APFSRL 391 LNK+NRKTFYTQDPVVGYTDYPFL P SRL Sbjct: 366 PLNKFNRKTFYTQDPVVGYTDYPFLQGNGSNGPLSRL 402 >5DXY-A nrPDB Length = 387 Score = 561 bits (1446), Expect = e-160, Method: Compositional matrix adjust. Identities = 260/377 (68%), Positives = 316/377 (83%), Gaps = 3/377 (0%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPG 70 TLFS+YKMG+F+LSHRVVLAP+TRCRA+N +PN AL EYY QR+T GGFLI+EGTM+SP Sbjct: 6 TLFSAYKMGKFNLSHRVVLAPLTRCRAINAIPNEALVEYYRQRSTAGGFLITEGTMISPS 65 Query: 71 SAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTN 130 SAGFPHVPGI++ EQVE WK+VV+A H +G IFCQLWHVGRASH VYQP G +PISST+ Sbjct: 66 SAGFPHVPGIFTKEQVEGWKKVVDAAHKEGAVIFCQLWHVGRASHQVYQPGGAAPISSTS 125 Query: 131 KPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHG 190 KPIS+ +W +LLPD ++ YP+PR L A+EI VVEDY ++A+NAI AGFDGIEIHGAHG Sbjct: 126 KPISK-KWEILLPDATYGTYPEPRPLAANEILEVVEDYRVAAINAIEAGFDGIEIHGAHG 184 Query: 191 YLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDATD 250 YL+DQF+KDGINDRTD+YGGS+ NRC+F+ QVV+ V +AIG +VG+R+SPAIDH DA D Sbjct: 185 YLLDQFMKDGINDRTDEYGGSLENRCKFILQVVQAVSAAIGTDRVGIRISPAIDHTDAMD 244 Query: 251 SDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHA--YGQTESGRQGSDEEEAKLMKS 308 SDP SLGLAV+ LNKLQ GS+LAYLHVTQPRY A +GQTE+G GS+EE A+LMK+ Sbjct: 245 SDPRSLGLAVIERLNKLQFKLGSRLAYLHVTQPRYTADGHGQTEAGANGSEEEVAQLMKT 304 Query: 309 LRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYNRK 368 R AY GTF+ GG+ +ELG+QAV QGDADLV++GR F++NPDLV R K++ LN+Y+R Sbjct: 305 WRGAYVGTFICCGGYTRELGLQAVAQGDADLVAFGRYFVSNPDLVLRLKLNAPLNRYDRA 364 Query: 369 TFYTQDPVVGYTDYPFL 385 TFYT DPVVGYTDYP L Sbjct: 365 TFYTHDPVVGYTDYPSL 381 >2Q3R-A nrPDB Length = 372 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 193/386 (50%), Positives = 260/386 (67%), Gaps = 19/386 (4%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 M + + L + YKMGRF+LSHRVVLAP+TR R+ VP A YY+QRTTPGGFL Sbjct: 1 MENGEAKQSVPLLTPYKMGRFNLSHRVVLAPLTRQRSYGNVPQPHAAIYYSQRTTPGGFL 60 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 I+E T VS + G+ PGI++ E VEAWK +V+AVHAKGG FCQ+WHVGR S++ +QP Sbjct: 61 ITEATGVSDTAQGYQDTPGIWTKEHVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNSGFQP 120 Query: 121 NGGSPISSTNKPISENRWRVLLPDG-SHVKYPKPRALEASEIPRVVEDYCLSALNAIRAG 179 NG +PIS ++KP+ + +G + PR L EIP +V D+ L+A NA+ AG Sbjct: 121 NGKAPISCSDKPLMPQ----IRSNGIDEALFTPPRRLGIEEIPGIVNDFRLAARNAMEAG 176 Query: 180 FDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRV 239 FDG+EIHGA+GYLIDQF+KD +NDRTD+YGGS+ NRC+F ++V+ V IG +VG+R+ Sbjct: 177 FDGVEIHGANGYLIDQFMKDTVNDRTDEYGGSLQNRCKFPLEIVDAVAKEIGPDRVGIRL 236 Query: 240 SPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSD 299 SP D++++ D++P +LGL + LNK + Y HV + R G+ + Sbjct: 237 SPFADYMESGDTNPGALGLYMAESLNKY------GILYCHVIEARMKTMGEVHAC----- 285 Query: 300 EEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKID 359 + +R A+ GTF+S+GGF +E G +AV +G DLV+YGR F+ANPDL RF++D Sbjct: 286 ---PHTLMPMRKAFKGTFISAGGFTREDGNEAVSKGRTDLVAYGRWFLANPDLPKRFQVD 342 Query: 360 GELNKYNRKTFYTQDPVVGYTDYPFL 385 LNKY+R TFYT DPVVGYTDYPFL Sbjct: 343 APLNKYDRPTFYTSDPVVGYTDYPFL 368 >1ICQ-A nrPDB Length = 376 Score = 387 bits (994), Expect = e-108, Method: Compositional matrix adjust. Identities = 188/376 (50%), Positives = 261/376 (69%), Gaps = 21/376 (5%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPGS 71 L S KMG+F+L HRVVLAP+TR R+ +P +Y+QR+T GG LI E T++S Sbjct: 16 LMSPCKMGKFELCHRVVLAPLTRQRSYGYIPQPHAILHYSQRSTNGGLLIGEATVISETG 75 Query: 72 AGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTNK 131 G+ VPGI++ EQVEAWK +V+AVHAKGG FCQ+WHVGR S+ +QPNG PIS T++ Sbjct: 76 IGYKDVPGIWTKEQVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNKDFQPNGEDPISCTDR 135 Query: 132 PISENRWRVLLPDGSHV-KYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHG 190 ++ ++ +G + + +PR L EIP++V ++ ++A NAI AGFDG+EIHGAHG Sbjct: 136 GLTPQ----IMSNGIDIAHFTRPRRLTTDEIPQIVNEFRVAARNAIEAGFDGVEIHGAHG 191 Query: 191 YLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDATD 250 YLIDQF+KD +NDR+D+YGGS+ NRCRF ++VE V + IG+ +VG+R+SP + +A D Sbjct: 192 YLIDQFMKDQVNDRSDKYGGSLENRCRFALEIVEAVANEIGSDRVGIRISPFAHYNEAGD 251 Query: 251 SDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYH-AYGQTESGRQGSDEEEAKLMKSL 309 ++P +LGL +V LNK LAY HV +PR A+ + E + + + Sbjct: 252 TNPTALGLYMVESLNKYD------LAYCHVVEPRMKTAWEKIEC---------TESLVPM 296 Query: 310 RMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYNRKT 369 R AY GTF+ +GG+++E G +A+ + ADLV+YGRLFI+NPDL RF+++ LNKYNR T Sbjct: 297 RKAYKGTFIVAGGYDREDGNRALIEDRADLVAYGRLFISNPDLPKRFELNAPLNKYNRDT 356 Query: 370 FYTQDPVVGYTDYPFL 385 FYT DP+VGYTDYPFL Sbjct: 357 FYTSDPIVGYTDYPFL 372 >4JIP-A nrPDB Length = 377 Score = 281 bits (719), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 156/384 (40%), Positives = 222/384 (57%), Gaps = 24/384 (6%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPG 70 +LF + G L++R+V+AP+TR R+ +PN A YY QR T G +++EGT +S Sbjct: 3 SLFEPAQAGDIALANRIVMAPLTRNRSPGAIPNNLNATYYEQRAT-AGLIVTEGTPISQQ 61 Query: 71 SAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTN 130 G+ VPG+Y E +E WK++ + VH+ GG I Q+WHVGR SH QP+GG P++ + Sbjct: 62 GQGYADVPGLYKREAIEGWKKITDGVHSAGGKIVAQIWHVGRISHTSLQPHGGQPVAPS- 120 Query: 131 KPISENRWRVLLPD---GSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHG 187 I+ ++ D G+ + +PRAL +I ++EDY A A+ AGFDG+EIH Sbjct: 121 -AITAKSKTYIINDDGTGAFAETSEPRALTIDDIGLILEDYRSGARAALEAGFDGVEIHA 179 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLD 247 A+GYLI+QFLK N RTD YGGSI NR RFL +VV+ V IGA + G+R+SP D Sbjct: 180 ANGYLIEQFLKSSTNQRTDDYGGSIENRARFLLEVVDAVAEEIGAGRTGIRLSPVTPAND 239 Query: 248 ATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMK 307 ++DP L VV L K LA++HV + G T R ++ Sbjct: 240 IFEADPQPLYNYVVEQLGK------RNLAFIHVVE------GATGGPRDFKQGDKPFDYA 287 Query: 308 SLRMAY-----NGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGEL 362 S + AY G ++++ G++++ ++AV+ G D V++G+ FIANPDLV R K D L Sbjct: 288 SFKAAYRNAGGKGLWIANNGYDRQSAIEAVESGKVDAVAFGKAFIANPDLVRRLKNDAPL 347 Query: 363 NKYNRKTFYTQDPVVGYTDYPFLA 386 N N+ TFY GYTDYP LA Sbjct: 348 NAPNQPTFYGGG-AEGYTDYPALA 370 >3GX9-A nrPDB Length = 377 Score = 279 bits (713), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 154/380 (40%), Positives = 211/380 (55%), Gaps = 19/380 (5%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMV 67 SN LF+ ++G L +RV++AP+TR R + VP YY QR + G +ISE T + Sbjct: 7 SNPGLFTPLQLGSLSLPNRVIMAPLTRSRTPDSVPGRLQQIYYGQRAS-AGLIISEATNI 65 Query: 68 SPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPIS 127 SP + G+ + PGI++D Q WK VVEAVHAKGG I QLWHVGR SH + QP+G P++ Sbjct: 66 SPTARGYVYTPGIWTDAQEAGWKGVVEAVHAKGGRIALQLWHVGRVSHELVQPDGQQPVA 125 Query: 128 STNKPISENRWRVLLPDGSHVKYPK--PRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 + V DG+ +P PRALE EIP +VEDY +A A RAGFD +E+ Sbjct: 126 PSALKAEGAECFVEFEDGTAGLHPTSTPRALETDEIPGIVEDYRQAAQRAKRAGFDMVEV 185 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 H A L +QFL G N RTDQYGGSI NR RF +VV+ V G +VG+R++P ++ Sbjct: 186 HAAAACLPNQFLATGTNRRTDQYGGSIENRARFPLEVVDAVAEVFGPERVGIRLTPFLEL 245 Query: 246 LDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKL 305 TD +P ++ + G L++ LAYLH +P + G Sbjct: 246 FGLTDDEPEAMAFYLAGELDR------RGLAYLHFNEPDWIG---------GDITYPEGF 290 Query: 306 MKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKY 365 + +R + G + G ++ + AD V++GR FIANPDL RF++ LN+ Sbjct: 291 REQMRQRFKGGLIYCGNYDAGRAQARLDDNTADAVAFGRPFIANPDLPERFRLGAALNEP 350 Query: 366 NRKTFYTQDPVVGYTDYPFL 385 + TFY VGYTDYPFL Sbjct: 351 DPSTFYG-GAEVGYTDYPFL 369 >4AEO-A nrPDB Length = 362 Score = 275 bits (703), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 163/383 (42%), Positives = 215/383 (56%), Gaps = 44/383 (11%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGFLISEGTMVSP 69 TLF K+G L +R+++AP+TRCRA G VPNA +AEYY QR + G ++SE T VSP Sbjct: 3 TLFDPIKLGDLQLPNRIIMAPLTRCRADEGRVPNALMAEYYVQRAS-AGLILSEATSVSP 61 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 G+P PGI++DEQV W V +AVHA GG IF QLWHVGR SH Y NG P++ + Sbjct: 62 MGVGYPDTPGIWNDEQVRGWNNVTKAVHAAGGRIFLQLWHVGRISHPSYL-NGELPVAPS 120 Query: 130 NKPISENRWRVLLPDGSHVK-------YPKPRALEASEIPRVVEDYCLSALNAIRAGFDG 182 + P G HV YP PRALE EI +VE Y A NA AGFDG Sbjct: 121 ----------AIQPKG-HVSLVRPLSDYPTPRALETEEINDIVEAYRSGAENAKAAGFDG 169 Query: 183 IEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPA 242 +EIHGA+GYL+DQFL+ N RTD+YGGS+ NR R L +V + + GA +VGV ++P Sbjct: 170 VEIHGANGYLLDQFLQSSTNQRTDRYGGSLENRARLLLEVTDAAIEVWGAQRVGVHLAPR 229 Query: 243 IDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEE 302 D D D+D V L K +A++ S + +D+ Sbjct: 230 ADAHDMGDADRAETFTYVARELGK------RGIAFIC-------------SREREADDSI 270 Query: 303 AKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGEL 362 L+K A+ G ++ + F+K A+ G AD V++G FIANPDL +R D L Sbjct: 271 GPLIKE---AFGGPYIVNERFDKASANAALASGKADAVAFGVPFIANPDLPARLAADAPL 327 Query: 363 NKYNRKTFYTQDPVVGYTDYPFL 385 N+ + +TFY + P VGY DYP L Sbjct: 328 NEAHPETFYGKGP-VGYIDYPRL 349 >3WJS-A nrPDB Length = 361 Score = 270 bits (691), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 155/377 (41%), Positives = 221/377 (58%), Gaps = 29/377 (7%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPGGFLISEGTMVSP 69 TLF G +R+V++P+TR RA VP +AEYYAQR + G +I+E T +S Sbjct: 3 TLFDPIDFGPIHAKNRIVMSPLTRGRADKEAVPTPIMAEYYAQRAS-AGLIITEATGISR 61 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS- 128 G+P PGI+SD QVEAWK +V VHAKGG I CQLWH+GR H+ G P+SS Sbjct: 62 EGLGWPFAPGIWSDAQVEAWKPIVAGVHAKGGKIVCQLWHMGRMVHSSV--TGTQPVSSS 119 Query: 129 -TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHG 187 T P + + P + + RA++A++I R++ DY +A NAIRAGFDG++IH Sbjct: 120 ATTAPGEVHTYEGKKP------FEQARAIDAADISRILNDYENAARNAIRAGFDGVQIHA 173 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLD 247 A+GYLID+FL++G N RTD+YGG NR RFLK+V E V++AIGA + GVR+SP D Sbjct: 174 ANGYLIDEFLRNGTNHRTDEYGGVPENRIRFLKEVTERVIAAIGADRTGVRLSPNGDTQG 233 Query: 248 ATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYH-AYGQTESGRQGSDEEEAKLM 306 DS P ++ + +L L +A+L + +P + +G+T ++ KL Sbjct: 234 CIDSAPETVFVPAAKLLQDL------GVAWLELREPGPNGTFGKT---------DQPKLS 278 Query: 307 KSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYN 366 +R + + + + E A+ +G AD +++GR FI+NPDL RF L + Sbjct: 279 PQIRKVFLRPLVLNQDYTFEAAQTALAEGKADAIAFGRKFISNPDLPERFARGIALQPDD 338 Query: 367 RKTFYTQDPVVGYTDYP 383 KT+Y+Q P GYTDYP Sbjct: 339 MKTWYSQGP-EGYTDYP 354 >4AWT-A nrPDB Length = 365 Score = 270 bits (689), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 151/380 (39%), Positives = 218/380 (57%), Gaps = 27/380 (7%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALAEYYAQRTTPGGFLISEGTMV 67 ++LF +G L +R+V+ P+TR RA V N +A YYAQR + G ++SEGT + Sbjct: 3 QSLFQPITLGALTLKNRIVMPPLTRSRASQPGDVANHMMAIYYAQRAS-AGLIVSEGTQI 61 Query: 68 SPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPIS 127 SP + G+ PGIY+ EQ+ W+ V EAVHAKG IF QLWHVGR +H +G PIS Sbjct: 62 SPTAKGYAWTPGIYTPEQIAGWRIVTEAVHAKGCAIFAQLWHVGRVTHP-DNIDGQQPIS 120 Query: 128 STNKPISENRWRVLLPDGSH----VKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGI 183 S+ + +V + +GS V PRA+ ++I +V+ DY +ALNA+ AGFDGI Sbjct: 121 SST--LKAENVKVFVDNGSDEPGFVDVAVPRAMTKADIAQVIADYRQAALNAMEAGFDGI 178 Query: 184 EIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAI 243 E+H A+GYLI+QF+ N+R+D+YGGS+ NR RFL +VV +V AIGA +VGVR++P Sbjct: 179 ELHAANGYLINQFIDSEANNRSDEYGGSLENRLRFLDEVVAALVDAIGAERVGVRLAPLT 238 Query: 244 DHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEA 303 D+DP+ A +LNK ++ YLH+ + + + + Sbjct: 239 TLNGTVDADPILTYTAAAALLNK------HRIVYLHIAEVDW----------DDAPDTPV 282 Query: 304 KLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELN 363 ++LR AY G + +G +N E QA+ G AD++ +GR FIANPDL R + L Sbjct: 283 SFKRALREAYQGVLIYAGRYNAEKAEQAINDGLADMIGFGRPFIANPDLPERLRHGYPLA 342 Query: 364 KYNRKTFYTQDPVVGYTDYP 383 ++ T + G TDYP Sbjct: 343 EHVPATLFGGGE-KGLTDYP 361 >3GKA-A nrPDB Length = 361 Score = 270 bits (689), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 159/383 (41%), Positives = 218/383 (56%), Gaps = 44/383 (11%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGFLISEGTMVSP 69 +LF +G L++R+++AP+TR RA + PNA +A YYA+R + G +ISE T V+P Sbjct: 11 SLFDPLTIGDLTLANRIIMAPLTRARAGDTRTPNALMARYYAERAS-AGLIISEATSVTP 69 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 G+ PGI+S EQV+ W+ V +AVHA GG IF QLWHVGR S V+ +G P++ + Sbjct: 70 QGVGYASTPGIWSPEQVDGWRLVTDAVHAAGGRIFLQLWHVGRVSDPVFL-DGALPVAPS 128 Query: 130 NKPISENRWRVLLPDGSHVK-------YPKPRALEASEIPRVVEDYCLSALNAIRAGFDG 182 + G HV Y PRALE EIP VV + A NA AGFDG Sbjct: 129 A-----------IAPGGHVSLVRPQRPYVTPRALELDEIPGVVAAFRRGAENARAAGFDG 177 Query: 183 IEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPA 242 +E+HGA+GYL+DQFL+D N RTD YGGSI NR R L +VV+ + A++VGV ++P Sbjct: 178 VEVHGANGYLLDQFLQDSANRRTDAYGGSIENRARLLLEVVDAAIDVWSAARVGVHLAPR 237 Query: 243 IDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEE 302 D DSDP A G + + G ++A+L + ++G G+Q Sbjct: 238 GDAHTMGDSDP----AATFGHVARELGRR--RIAFLFARE----SFGGDAIGQQ------ 281 Query: 303 AKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGEL 362 L+ A+ G F+ + F + A+ G AD V++G+LFIANPDL RFK++ L Sbjct: 282 ------LKAAFGGPFIVNENFTLDSAQAALDAGQADAVAWGKLFIANPDLPRRFKLNAPL 335 Query: 363 NKYNRKTFYTQDPVVGYTDYPFL 385 N+ N TFY Q VGYTDYP L Sbjct: 336 NEPNAATFYAQGE-VGYTDYPAL 357 >5EPD-A nrPDB Length = 385 Score = 269 bits (687), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 152/378 (40%), Positives = 212/378 (56%), Gaps = 25/378 (6%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGFLISEGTM 66 + TLF +G L++R+V+AP+TR RA G VP A YYAQR + G +ISE T Sbjct: 22 TKTTLFQPTSLGAITLANRIVMAPLTRNRAGAGFVPGELTAGYYAQRAS-AGLIISEATQ 80 Query: 67 VSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPI 126 +S G+ PGIY+ Q++ WK+V AVH KGG I QLWHVGR SH QPNGG+P+ Sbjct: 81 ISQQGQGYQDTPGIYTQAQIDGWKKVTAAVHKKGGRIVLQLWHVGRISHVNLQPNGGAPV 140 Query: 127 SSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIH 186 + P + + V +PRALE E+ +V+D+ +A N+I AGFDG+E+H Sbjct: 141 A----PSAIRAEVKTFVNNGFVDVSEPRALELEELAGIVDDFRKAAANSIEAGFDGVEVH 196 Query: 187 GAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHL 246 GA+GYL++QF KDG N RTD YGGS+ NR R + +V V IG + G+R+SP Sbjct: 197 GANGYLLEQFAKDGANMRTDTYGGSVENRARLMLEVTAAVAQEIGPERTGIRISPVSPAN 256 Query: 247 DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKL- 305 + SDP + +V L+ L +AY+HV + G G + A Sbjct: 257 GISCSDPQTQYDYIVDKLDAL------GIAYIHVVE-----------GATGGPRDVAPFD 299 Query: 306 MKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKY 365 SLR ++ T++++ GF+ EL + G ADL+++GR FIANPDLV R + L + Sbjct: 300 YGSLRRRFSRTYIANNGFDLELATSHLADGRADLIAFGRPFIANPDLVERLQSGAPLAEV 359 Query: 366 NRKTFYTQDPVVGYTDYP 383 N + GYTDYP Sbjct: 360 NAAKIFGGS-AAGYTDYP 376 >4QNW-A nrPDB Length = 392 Score = 252 bits (643), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 147/392 (37%), Positives = 212/392 (54%), Gaps = 34/392 (8%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRAL-NGVPNAALAEYYAQR-TTPGGFLISEGT 65 S+ LF K+GR L HR+++AP TR RA GVP + EYY QR + PG LI+E T Sbjct: 6 SSAQLFKPLKVGRCHLQHRMIMAPTTRFRADGQGVPLPFVQEYYGQRASVPGTLLITEAT 65 Query: 66 MVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSP 125 ++P + G+ HVPGI+S+ Q EAW+++V VH+K FIFCQLW GRA+ + Sbjct: 66 DITPKAMGYKHVPGIWSEPQREAWREIVSRVHSKKCFIFCQLWATGRAADPDVLADMKDL 125 Query: 126 ISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 ISS+ P+ E K P PRAL EI + + D+ +A NAI AGFDG+EI Sbjct: 126 ISSSAVPVEE-------------KGPLPRALTEDEIQQCIADFAQAARNAINAGFDGVEI 172 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 HGA+GYLIDQF + N R D++GGSI NR RF +V V+ A+GA +VGV++SP + Sbjct: 173 HGANGYLIDQFTQKSCNHRQDRWGGSIENRARFAVEVTRAVIEAVGADRVGVKLSPYSQY 232 Query: 246 LDATDSDPLSLGLA-VVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAK 304 L D L ++ + +L +AYLH+ R+ + + D Sbjct: 233 LGMGTMDELVPQFEYLIAQMRRLD------VAYLHLANSRW-----LDEEKPHPDPNHEV 281 Query: 305 LMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADL-----VSYGRLFIANPDLVSRFKID 359 ++ + + +GG++ + +Q A +++GR FI+ PDL R Sbjct: 282 FVRV--WGQSSPILLAGGYDAASAEKVTEQMAAATYTNVAIAFGRYFISTPDLPFRVMAG 339 Query: 360 GELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 +L KY+R +FY+ GY DYPF A + L Sbjct: 340 IQLQKYDRASFYSTLSREGYLDYPFSAEYMAL 371 >4A3U-A nrPDB Length = 358 Score = 249 bits (636), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 148/380 (38%), Positives = 211/380 (55%), Gaps = 31/380 (8%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRAL-NGVPNAALAEYYAQRTTPGGFLISEGTMVSP 69 +LF + G F +R+ +AP+TR RA + VP +AEYYAQR + G +ISE T +S Sbjct: 3 SLFDPIRFGAFTAKNRIWMAPLTRGRATRDHVPTEIMAEYYAQRAS-AGLIISEATGISQ 61 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPI--S 127 G+P+ PGI+SD QVEAW + +AVH GG IF QLWH+GR + +G P+ S Sbjct: 62 EGLGWPYAPGIWSDAQVEAWLPITQAVHDAGGLIFAQLWHMGRMVPS--NVSGMQPVAPS 119 Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHG 187 ++ P + + DG Y RAL EIPR+++DY +A +A++AGFDG++IH Sbjct: 120 ASQAPGLGHTY-----DGKK-PYDVARALRLDEIPRLLDDYEKAARHALKAGFDGVQIHA 173 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLD 247 A+GYLID+F++D N R D+YGG++ NR R LK V E V++ IG + VR+SP + Sbjct: 174 ANGYLIDEFIRDSTNHRHDEYGGAVENRIRLLKDVTERVIATIGKERTAVRLSPNGEIQG 233 Query: 248 ATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGS--DEEEAKL 305 DS P + + ML+ L +A+L G E G+ ++ KL Sbjct: 234 TVDSHPEQVFIPAAKMLSDLD------IAFL----------GMREGAVDGTFGKTDQPKL 277 Query: 306 MKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKY 365 +R + + + + E A+ G AD +S+GR FI NPDL RF L K Sbjct: 278 SPEIRKVFKPPLVLNQDYTFETAQAALDSGVADAISFGRPFIGNPDLPRRFFEKAPLTKD 337 Query: 366 NRKTFYTQDPVVGYTDYPFL 385 +T+YTQ P GYTDYP L Sbjct: 338 VIETWYTQTP-KGYTDYPLL 356 >6GI9-A nrPDB Length = 373 Score = 244 bits (624), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 144/384 (37%), Positives = 210/384 (54%), Gaps = 26/384 (6%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALAEYYAQRTTPGGFLISEGT 65 S E LF+ K+G +RV +AP+TR R++ +P + EYY QR + G +ISE T Sbjct: 2 SAEKLFTPLKVGAVTAPNRVFMAPLTRLRSIEPGDIPTPLMGEYYRQRAS-AGLIISEAT 60 Query: 66 MVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSP 125 +S + G+ PG++S EQ+ AWK++ VHA+ G I QLWH GR SH+ QP G +P Sbjct: 61 QISAQAKGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQLWHTGRLSHSSIQPGGQAP 120 Query: 126 ISSTNKPISENRWRVLLPDGS----HVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFD 181 +S++ ++ N R L D + V PRALE EIP +V D+ + NA AGFD Sbjct: 121 VSAS--ALNANT-RTSLRDENGNAIRVDTTTPRALELDEIPGIVNDFRQAVANAREAGFD 177 Query: 182 GIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSP 241 +E+H AHGYL+ QFL N RTDQYGGS+ NR R + +VV+ V + A ++G+RVSP Sbjct: 178 LVELHSAHGYLLHQFLSPSSNQRTDQYGGSVENRARLVLEVVDAVCNEWSADRIGIRVSP 237 Query: 242 AIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEE 301 I D+ P A L ++ + +AYLH+ +E+ G Sbjct: 238 -IGTFQNVDNGPNEEADA----LYLIEELAKRGIAYLHM----------SETDLAGGKPY 282 Query: 302 EAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGE 361 + +R ++G + +G + E + +G D V++GR +IANPDLV+R + E Sbjct: 283 SEAFRQKVRERFHGVIIGAGAYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAE 342 Query: 362 LNKYNRKTFYTQDPVVGYTDYPFL 385 LN ++FY GYTDYP L Sbjct: 343 LNPQRPESFYGGG-AEGYTDYPSL 365 >5K1Q-A nrPDB Length = 355 Score = 227 bits (578), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 132/366 (36%), Positives = 200/366 (54%), Gaps = 32/366 (8%) Query: 7 NSNETLFSSYKMG-RFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPGGFLISEG 64 NS E LF +YK+ L +R+++AP+TRC A N VP + YYA+R G +ISE Sbjct: 8 NSVENLFDTYKLNDTITLKNRILMAPLTRCMADANLVPTDDMVAYYARRA-EAGLIISEA 66 Query: 65 TMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGS 124 T++ P + G+P+ PGI++ Q+ W++V +AVHA GG IF QLWH GR +H + GG Sbjct: 67 TIIRPDAQGYPNTPGIFTQAQIAGWRKVTDAVHANGGKIFVQLWHTGRVAHPHFF-GGGD 125 Query: 125 PISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 ++ + + I + +P + Y P+A+ +I +V DY +A N I AGFDG+E Sbjct: 126 VLAPSAQKIEGS-----VPRMRELTYVTPKAVTVEDIQGLVRDYAKAAENVIEAGFDGVE 180 Query: 185 IHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAID 244 IHGA+GYLIDQFL N RTD+YGG+ N RF +VV+ +++ IG + G+R+SP Sbjct: 181 IHGANGYLIDQFLHHDSNRRTDEYGGTPVNMSRFALEVVDAIIARIGHDRTGLRISPGAY 240 Query: 245 HLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHV----TQPRYHAYGQTESGRQGSDE 300 A+DS + ++ L K LA++H+ + G T S Sbjct: 241 FNMASDSRDRVVFDYLLPELEK------RDLAFVHIGIFDDSIEFDYLGGTAS------- 287 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 +R Y T + G ++ E +A+ + DL++ GR FIANPD V++ + Sbjct: 288 ------SYVRAHYGKTLVGVGSYSAETASKAIAEDKFDLIAIGRPFIANPDYVAKVRNSE 341 Query: 361 ELNKYN 366 EL Y+ Sbjct: 342 ELVAYS 347 >5V4P-A nrPDB Length = 400 Score = 218 bits (554), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 139/386 (36%), Positives = 211/386 (54%), Gaps = 23/386 (5%) Query: 9 NETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALAE-YYAQRTT-PGGFLISEG 64 + LF K+G L+HR V+ P+TR RA + +PN A YY QR PG +I+EG Sbjct: 14 DTNLFEPIKIGNTQLAHRAVMPPLTRMRATHPGNIPNKEWAAVYYGQRAQRPGTMIITEG 73 Query: 65 TMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHA-VYQPNGG 123 T +SP + G+ + PGI+SDEQV WK + A+H F + QLW +G AS V +G Sbjct: 74 TFISPQAGGYDNAPGIWSDEQVAEWKNIFLAIHDCQSFAWVQLWSLGWASFPDVLARDGL 133 Query: 124 SPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGI 183 ++++ + D +++++ +L +I + ++DY +A N+I AG DG+ Sbjct: 134 RYDCASDRVYMNATLQEKAKDANNLEH----SLTKDDIKQYIKDYIHAAKNSIAAGADGV 189 Query: 184 EIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSP-- 241 EIH A+GYL++QFL N RTD+YGG+I NR RF +VV+ ++ IG +VG+R+SP Sbjct: 190 EIHSANGYLLNQFLDPHSNKRTDEYGGTIENRARFTLEVVDALIETIGPERVGLRLSPYG 249 Query: 242 AIDHLD-ATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 + + + ++ V+G L K + G +LA++H+ +PR S +G E Sbjct: 250 TFNSMSGGAEPGIIAQYSYVLGELEK-RAKAGKRLAFVHLVEPRV----TDPSLVEGEGE 304 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD---LVSYGRLFIANPDLVSRFK 357 + G + +G N L + V++ D L+ YGR FI+NPDLV R + Sbjct: 305 YSEGTNDFAYSIWKGPIIRAG--NYALHPEVVREQVKDPRTLIGYGRFFISNPDLVYRLE 362 Query: 358 IDGELNKYNRKTFYTQDPVVGYTDYP 383 LNKY+R TFYT GYTDYP Sbjct: 363 EGLPLNKYDRSTFYTMS-AEGYTDYP 387 >4E2D-A nrPDB Length = 382 Score = 214 bits (545), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 139/389 (35%), Positives = 211/389 (54%), Gaps = 37/389 (9%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRALNG--VPNA-ALAEYYAQRTTPGGFLISEGTMVS 68 L K+GR+ L +R+++AP+TRC+A VP ++ +YY R + G +I+E TMV Sbjct: 10 LLRPLKLGRYTLRNRIIMAPLTRCQATEDGHVPRTESMLKYYEDRAS-AGLIIAEATMVQ 68 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRA---SHAVYQPN---- 121 P GF PGIYSD Q+E W+++V+AVH KGG IF QL H GRA + QP Sbjct: 69 PNYTGFLTEPGIYSDAQIEEWRKIVDAVHKKGGLIFLQLIHAGRAGIPEKILQQPKSDQD 128 Query: 122 --GGSPISSTNKPISENRWRVLL-PDGSHVKYPKPRALEASEIPR-VVEDYCLSALNAI- 176 G ++++ PI ++R G Y P L E+ ++ + A NAI Sbjct: 129 PLAGRLLAASAIPIKDHRIPAYFAASGEKETYGVPEELTDDEVRNGIIPLFVEGAKNAIF 188 Query: 177 RAGFDGIEIHGAHGYLIDQFLKDGINDR-TDQYGG-SIANRCRFLKQVVEGVVSAIGASK 234 +AGFDG+EIHGA+GYL+D F ++ N R + Y G +I RC+ + V + V A+G+ + Sbjct: 189 KAGFDGVEIHGANGYLLDAFFRESSNKRQSGPYAGTTIDTRCQLIYDVTKSVCDAVGSDR 248 Query: 235 VGVRVSPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESG 294 VG+R+SP DS+P +L + + L LAYLH + G + Sbjct: 249 VGLRISPLNGVHGMIDSNPEALTKHLCKKIEPLS------LAYLHYLR------GDMVNQ 296 Query: 295 RQGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVS 354 + G ++ +R +Y+G +S+ ++ E Q +++G D V++G FIANPDLV Sbjct: 297 QIGD------VVAWVRGSYSGVKISNLRYDFEEADQQIREGKVDAVAFGAKFIANPDLVE 350 Query: 355 RFKIDGELNKYNRKTFYTQDPVVGYTDYP 383 R + D LN+ +T+YT+ VGY DYP Sbjct: 351 RAQHDWPLNEPRPETYYTRT-AVGYNDYP 378 >4GBU-A nrPDB Length = 400 Score = 213 bits (541), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 145/391 (37%), Positives = 213/391 (54%), Gaps = 25/391 (6%) Query: 4 AQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALA-EYYAQRTT-PGGF 59 A G++N LF K+G +L HR V+ P+TR RAL+ +PN A EYY QR PG Sbjct: 11 ALGDTN--LFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTM 68 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQ 119 +I+EG +SP + G+ + PG++S+EQ+ W ++ A+H K F++ QL +G A+ Sbjct: 69 IITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLAVLGWAAFPDNL 128 Query: 120 PNGGSPISSTNKPISENRWRVLLPDGSHVKYPKPR-ALEASEIPRVVEDYCLSALNAIRA 178 G S S+N + + K P+ +L EI + +++Y +A N+I A Sbjct: 129 ARDGLRYDSA----SDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEYVQAAKNSIAA 184 Query: 179 GFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVR 238 G DG+EIH A+GYL++QFL N RTD+YGGSI NR RF +VV+ +V AIG KVG+R Sbjct: 185 GADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIENRARFTLEVVDALVEAIGHEKVGLR 244 Query: 239 VSP--AIDHLDATDSDPLSLGLA-VVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGR 295 +SP + + + A V G L K + G +LA++H+ +PR TE Sbjct: 245 LSPYGVFNSMSGGAETGIVAQYAYVAGELEK-RAKAGKRLAFVHLVEPRVTNPFLTEGEG 303 Query: 296 QGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD---LVSYGRLFIANPDL 352 + + S+ + G + +G F L + V++ D L+ YGR FI+NPDL Sbjct: 304 EYEGGSN-DFVYSI---WKGPVIRAGNF--ALHPEVVREEVKDKRTLIGYGRFFISNPDL 357 Query: 353 VSRFKIDGELNKYNRKTFYTQDPVVGYTDYP 383 V R + LNKY+R TFY Q GY DYP Sbjct: 358 VDRLEKGLPLNKYDRDTFY-QMSAHGYIDYP 387 >4TMB-A nrPDB Length = 403 Score = 201 bits (512), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 143/392 (36%), Positives = 214/392 (54%), Gaps = 31/392 (7%) Query: 6 GNSNETLFSSYKMGRFDLSHRVVLAPMTRCRAL--NGVPNAALAE-YYAQRTT-PGGFLI 61 G++N +F K+G +L HRVV+ +TR RA+ +PN AE YY QR+ PG +I Sbjct: 12 GDTN--IFKPIKIGNNELKHRVVMPALTRMRAIAPGNIPNTEWAEEYYRQRSQYPGTLII 69 Query: 62 SEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGR-ASHAVYQP 120 +EGT S S G+P+VPGI+S EQ+ WK++ A+H F++ QLW +GR A V + Sbjct: 70 TEGTFPSAQSGGYPNVPGIWSKEQLAEWKKIFNAIHENKSFVWVQLWVLGRQAWPEVLKK 129 Query: 121 NGGSPISSTNKPI--SENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRA 178 G S+T+ E + R L + + EI + +++Y +A AI A Sbjct: 130 EGLRYDSATDDLYMGEEEKERALKANNPQ------HGITKEEIKQYIKEYVDAAKKAIDA 183 Query: 179 GFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVR 238 G DG++IH A+GYL++QFL N+RTD+YGGSI NR RF +VV+ VV A+GA + +R Sbjct: 184 GADGVQIHSANGYLLNQFLDPISNNRTDEYGGSIENRARFTLEVVDAVVDAVGAERTSIR 243 Query: 239 VSP--AIDHLDATDSDPLSLGLA-VVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGR 295 SP + ++ + A V+G L K + G +LA++ + +PR E + Sbjct: 244 FSPYGTFGTMSGGENPGIVAQYAYVIGELEK-RARAGKRLAFIDLVEPRVTDPFLPEFEK 302 Query: 296 ---QGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD-LVSYGRLFIANPD 351 +G++E + S+ + G + G + + + + L+ YGR FIANPD Sbjct: 303 WFKEGTNE----FIYSI---WKGPVLRVGNYALDPDQATLDSKKPNTLIGYGRSFIANPD 355 Query: 352 LVSRFKIDGELNKYNRKTFYTQDPVVGYTDYP 383 LV R + LNKY+R TFYT GYTDYP Sbjct: 356 LVYRLEKGLPLNKYDRNTFYTFTK-EGYTDYP 386 >4QAI-A nrPDB Length = 407 Score = 197 bits (500), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 134/386 (34%), Positives = 209/386 (54%), Gaps = 32/386 (8%) Query: 13 FSSYKMGRFDLSHRVVLAPMTRCRAL-NGVPNAALAEYYAQRTT-PGGFLISEGTMVSPG 70 F S K+G L ++V P TR RAL + P+ +YY R+T PG LI+E T VSP Sbjct: 15 FQSIKVGNNTLQTKIVYPPTTRFRALEDHTPSDLQLQYYGDRSTFPGTLLITEATFVSPQ 74 Query: 71 SAGFP-HVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGR-ASHAVYQPNGGSPISS 128 ++G+ PGI++D+ +AWK + + VHA G F+ QL +GR A AV + G +P+S+ Sbjct: 75 ASGWEGAAPGIWTDKHAKAWKVITDKVHANGSFVSTQLIFLGRVADPAVMKTRGLNPVSA 134 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVV-EDYCLSALNAIRAGFDGIEIHG 187 + S+ G+ V RAL E+ +V E Y +A A+ AGFD IE+H Sbjct: 135 SATYESDAAKEAAEAVGNPV-----RALTTQEVKDLVYEAYTNAAQKAMDAGFDYIELHA 189 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAID--- 244 AHGYL+DQFL+ N RTD+YGGSI NR R + ++++ + + +GA K+G+R+SP Sbjct: 190 AHGYLLDQFLQPCTNQRTDEYGGSIENRARLILELIDHLSTIVGADKIGIRISPWATFQN 249 Query: 245 ---HLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHA-YGQTESGRQGSDE 300 H D PL+ +V L + + G +AY+ V +PR +E + G +E Sbjct: 250 MKAHKDTV--HPLTTFSYLVHELQQ-RADKGQGIAYISVVEPRVSGNVDVSEEDQAGDNE 306 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKEL-GMQAVQQGDAD---LVSYGRLFIANPDLVSRF 356 +K+ K G + +G ++ + + +++ AD LV + R F +NP+LV + Sbjct: 307 FVSKIWK-------GVILKAGNYSYDAPEFKTLKEDIADKRTLVGFSRYFTSNPNLVWKL 359 Query: 357 KIDGELNKYNRKTFYTQDPVVGYTDY 382 + +L Y+R TFY+ D GY + Sbjct: 360 RDGIDLVPYDRNTFYS-DNNYGYNTF 384 >4RNU-A nrPDB Length = 400 Score = 184 bits (466), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 111/289 (38%), Positives = 166/289 (57%), Gaps = 15/289 (5%) Query: 4 AQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALA-EYYAQRTT-PGGF 59 A G++N LF K+G +L HR V+ P+TR RAL+ +PN A EYY QR PG Sbjct: 109 ALGDTN--LFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTM 166 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQ 119 +I+EG +SP + G+ + PG++S+EQ+ W ++ A+H K F++ QLW +G A+ Sbjct: 167 IITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLWVLGWAAFPDNL 226 Query: 120 PNGGSPISSTNKPISENRWRVLLPDGSHVKYPKPR-ALEASEIPRVVEDYCLSALNAIRA 178 G S S+N + + K P+ +L EI + +++Y +A N+I A Sbjct: 227 ARDGLRYDSA----SDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEYVQAAKNSIAA 282 Query: 179 GFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVR 238 G DG+EIH A+GYL++QFL N RTD+YGGSI NR RF +VV+ +V AIG KVG+R Sbjct: 283 GADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIENRARFTLEVVDALVEAIGHEKVGLR 342 Query: 239 VSP--AIDHLDATDSDPLSLGLA-VVGMLNKLQGVNGSKLAYLHVTQPR 284 +SP + + + A V G L K + G +LA++H+ +PR Sbjct: 343 LSPYGVFNSMSGGAETGIVAQYAYVAGELEK-RAKAGKRLAFVHLVEPR 390 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 32/74 (43%), Positives = 42/74 (56%), Gaps = 6/74 (8%) Query: 313 YNGTFMSSGGFNKELGMQAVQQGDAD---LVSYGRLFIANPDLVSRFKIDGELNKYNRKT 369 + G + +G F L + V++ D L+ YGR FI+NPDLV R + LNKY+R T Sbjct: 16 WKGPVIRAGNF--ALHPEVVREEVKDKRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDT 73 Query: 370 FYTQDPVVGYTDYP 383 FY Q GY DYP Sbjct: 74 FY-QMSAHGYIDYP 86 >4RNX-A nrPDB Length = 400 Score = 138 bits (347), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 92/235 (39%), Positives = 131/235 (55%), Gaps = 14/235 (5%) Query: 155 ALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIAN 214 +L EI + +++Y +A N+I AG DG+EIH A+GYL++QFL N RTD+YGGSI N Sbjct: 9 SLTKDEIKQYIKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIEN 68 Query: 215 RCRFLKQVVEGVVSAIGASKVGVRVSP--AIDHLDATDSDPLSLGLA-VVGMLNKLQGVN 271 R RF +VV+ +V AIG KVG+R+SP + + + A V G L K + Sbjct: 69 RARFTLEVVDALVEAIGHEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVAGELEK-RAKA 127 Query: 272 GSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQA 331 G +LA++H+ +PR TE + + S+ + G + +G F L + Sbjct: 128 GKRLAFVHLVEPRVTNPFLTEGEGEYEGGSN-DFVYSI---WKGPVIRAGNF--ALHPEV 181 Query: 332 VQQGDAD---LVSYGRLFIANPDLVSRFKIDGELNKYNRKTFYTQDPVVGYTDYP 383 V++ D L+ YGR FI+NPDLV R + LNKY+R TFY Q GY DYP Sbjct: 182 VREEVKDKRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFY-QMSAHGYIDYP 235 Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 48/115 (41%), Positives = 73/115 (63%), Gaps = 6/115 (5%) Query: 4 AQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALA-EYYAQRTT-PGGF 59 A G++N LF K+G +L HR V+ P+TR RAL+ +PN A EYY QR PG Sbjct: 258 ALGDTN--LFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTM 315 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRAS 114 +I+EG +SP + G+ + PG++S+EQ+ W ++ A+H K F++ QLW +G A+ Sbjct: 316 IITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLWVLGWAA 370 >3KRZ-A nrPDB Length = 337 Score = 124 bits (312), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 102/345 (29%), Positives = 164/345 (47%), Gaps = 40/345 (11%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPG-GFLISEGTMVSP 69 L K+ + +R++++PM A +G+PN +YA R G G ++ E T V Sbjct: 4 LHMPLKIKDITIKNRIMMSPMCMYSASTDGMPNDWHIVHYATRAIGGVGLIMQEATAVES 63 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPN-GGSPISS 128 H GI++DEQV+ K++V+ A G + QL H GR + Y+ G SPI + Sbjct: 64 RGRITDHDLGIWNDEQVKELKKIVDICKANGAVMGIQLAHAGRKCNISYEDVVGPSPIKA 123 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 ++ Y PR L EI +V+ + +A A AG+D +EIH A Sbjct: 124 GDR------------------YKLPRELSVEEIKSIVKAFGEAAKRANLAGYDVVEIHAA 165 Query: 189 HGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASK-VGVRVSPAIDHLD 247 HGYLI +FL N R D+YG SI NR RFL +V++ V +K + VRVS A D+++ Sbjct: 166 HGYLIHEFLSPLSNKRKDEYGNSIENRARFLIEVIDEVRKNWPENKPIFVRVS-ADDYME 224 Query: 248 ATDSDPLSLGLAVVGML-NKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 + + + + + M+ +K+ ++ S L+V Y Y + K Sbjct: 225 GGIN--IDMMVEYINMIKDKVDLIDVSSGGLLNVDINLYPGY-------------QVKYA 269 Query: 307 KSLRMAYNGTFMSSGGF-NKELGMQAVQQGDADLVSYGRLFIANP 350 ++++ N + G +EL + + ADLV+ GR + NP Sbjct: 270 ETIKKRCNIKTSAVGLITTQELAEEILSNERADLVALGRELLRNP 314 >5OCS-A nrPDB Length = 371 Score = 117 bits (293), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 83/236 (35%), Positives = 120/236 (50%), Gaps = 13/236 (5%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPG-GFLISEGTMVSPG 70 LF Y++G +L++R+ +APM + A G + Q G G LI E T VSP Sbjct: 4 LFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAVSPE 63 Query: 71 SAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGF-IFCQLWHVGRASHAVYQPNGGSPISST 129 P G+Y+D A +V+ AV + QL H GR + + +GG I Sbjct: 64 GRITPTDLGLYNDANEAALGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQI--- 120 Query: 130 NKPISENRWRVLLPDGSHVKYPK----PRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 +P W+ P S V + P AL+ + + ++ +D+ +A A R G +GIE+ Sbjct: 121 -RPDQPRGWQTFAP--SAVPHAAGEVPPAALDKAGMKKIRDDFVAAAKRAARLGIEGIEV 177 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASK-VGVRVS 240 HGAHGYL+ QFL N RTD+YGGS+ NR RF +V + V A A + V +RVS Sbjct: 178 HGAHGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVS 233 >5CPN-A nrPDB Length = 371 Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 103/351 (29%), Positives = 153/351 (43%), Gaps = 32/351 (9%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPG-GFLISEGTMVSP 69 LF Y + L +R+ + PM + A +G+ N +YA G G L+ E T V+P Sbjct: 3 ALFEPYTLKDVTLRNRIAIPPMCQYMAEDGLINDWHQVHYASMARGGAGLLVVEATAVAP 62 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 P GI+SD +A+ VV+A+ A G Q+ H GR + A G I + Sbjct: 63 EGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIGAD 122 Query: 130 NKPISENRWRVLLPD----GSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 + W + P G+H+ PRA+ +I RV +D+ +A A AGF+ IE+ Sbjct: 123 DA----RGWETIAPSAIAFGAHLPN-VPRAMTLDDIARVKQDFVDAARRARDAGFEWIEL 177 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 H AHGYL F + N RTD YGGS NR RFL + + V + + + + Sbjct: 178 HFAHGYLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETL-AAVREVWPENLPLTARFGVLE 236 Query: 246 LDATDSDPL--SLGLA---VVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 D D L S+ LA G L+ L G + ++ +G G Sbjct: 237 YDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPETNIP------WGPAFMG------ 284 Query: 301 EEAKLMKSLRMAYNGTFMSSGGF-NKELGMQAVQQGDADLVSYGRLFIANP 350 + + +R S+ GF +L A+Q DLVS GR +A+P Sbjct: 285 ---PIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADP 332 >3GR7-A nrPDB Length = 340 Score = 114 bits (284), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 104/348 (29%), Positives = 152/348 (43%), Gaps = 41/348 (11%) Query: 9 NETLFSSYKMGRFDLSHRVVLAPMT--RCRALNGVPNAALAEYYAQRTT-PGGFLISEGT 65 N LFS Y + L +R+V++PM C +G +Y R G +I E T Sbjct: 2 NTMLFSPYTIRGLTLKNRIVMSPMCMYSCDTKDGAVRTWHKIHYPARAVGQVGLIIVEAT 61 Query: 66 MVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSP 125 V+P GI+SD+ + +++V V G I QL H GR S G Sbjct: 62 GVTPQGRISERDLGIWSDDHIAGLRELVGLVKEHGAAIGIQLAHAGRKSQV-----PGEI 116 Query: 126 ISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 I+ + P ++ P P+ + ++I V+ + A A AGFD IEI Sbjct: 117 IAPSAVPFDDSS-------------PTPKEMTKADIEETVQAFQNGARRAKEAGFDVIEI 163 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 H AHGYLI++FL N R D+YGGS NR RFL +V++ V + + VR+S + H Sbjct: 164 HAAHGYLINEFLSPLSNRRQDEYGGSPENRYRFLGEVIDA-VREVWDGPLFVRISASDYH 222 Query: 246 ---LDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEE 302 L A D P + + K QGV+ ++ + R + Y G Q E Sbjct: 223 PDGLTAKDYVPYAKRM-------KEQGVDLVDVSSGAIVPARMNVY----PGYQVPFAEL 271 Query: 303 AKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANP 350 + + G S G+ E + +Q G ADLV GR + NP Sbjct: 272 IRREADIPTGAVGLITS--GWQAE---EILQNGRADLVFLGRELLRNP 314 >1Z48-A nrPDB Length = 338 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 96/347 (27%), Positives = 154/347 (44%), Gaps = 45/347 (12%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAAL-----AEYYAQRTTPGGFLISEGTM 66 LF+ + L +R+V++PM C + + L A Y ++ G +I E + Sbjct: 5 LFTPITIKDMTLKNRIVMSPM--CMYSSHEKDGKLTPFHMAHYISRAIGQVGLIIVEASA 62 Query: 67 VSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHA---VYQPNGG 123 V+P GI+SDE +E + ++ E V +G I QL H GR + ++ P+ Sbjct: 63 VNPQGRITDQDLGIWSDEHIEGFAKLTEQVKEQGSKIGIQLAHAGRKAELEGDIFAPSAI 122 Query: 124 SPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGI 183 + + P+ + A ++ V+++ +A A AGFD I Sbjct: 123 AFDEQSATPVE---------------------MSAEKVKETVQEFKQAAARAKEAGFDVI 161 Query: 184 EIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAI 243 EIH AHGYLI +FL N RTD+YGGS NR RFL+++++ V + + VRVS A Sbjct: 162 EIHAAHGYLIHEFLSPLSNHRTDEYGGSPENRYRFLREIIDE-VKQVWDGPLFVRVS-AS 219 Query: 244 DHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEA 303 D+ D +G A + ++ S A +H + Y Q S E Sbjct: 220 DYTDKGLDIADHIGFAKWMKEQGVDLIDCSSGALVHADINVFPGY-------QVSFAE-- 270 Query: 304 KLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANP 350 K+ + MA M + G + + +Q G ADL+ GR + +P Sbjct: 271 KIREQADMATGAVGMITDG---SMAEEILQNGRADLIFIGRELLRDP 314 >1PS9-A nrPDB Length = 671 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 98/356 (27%), Positives = 171/356 (48%), Gaps = 48/356 (13%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAA--LAEYYAQRTTPGGFLISEGTMVS 68 +LF+ +G L +RV++ M L P+ A LA +YA+R G LI G ++ Sbjct: 4 SLFAPLDLGFTTLKNRVLMGSMHT--GLEEYPDGAERLAAFYAERARHGVALIVSGG-IA 60 Query: 69 PGSAGFPHVPGIYSDE--QVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPI 126 P G G ++ Q+ + + EAVH +GG I Q+ H GR S YQP+ +P Sbjct: 61 PDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQILHTGRYS---YQPHLVAP- 116 Query: 127 SSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIH 186 S+ PI NR+ P L EI ++++++ A A AG+DG+E+ Sbjct: 117 SALQAPI--NRF-------------VPHELSHEEILQLIDNFARCAQLAREAGYDGVEVM 161 Query: 187 GAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHL 246 G+ GYLI++FL N R+DQ+GG NR RF +VV V +G + + +D + Sbjct: 162 GSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSMLDLV 221 Query: 247 D--ATDSDPLSLGLAV----VGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 + T ++ + L A+ ++N G + +++ + PR A+ Sbjct: 222 EDGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPR-GAF------------ 268 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNK-ELGMQAVQQGDADLVSYGRLFIANPDLVSR 355 + + + L+ + +++ N ++ + +GDAD+VS R F+A+ +L+S+ Sbjct: 269 --SWVTRKLKGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSK 322 >3HF3-A nrPDB Length = 349 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 78/243 (32%), Positives = 114/243 (46%), Gaps = 20/243 (8%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPG-GFLISEGTMVSP 69 LF+ ++G L +R+ ++PM + A L G +Y R G G ++ E T V P Sbjct: 4 LFTPLELGGLRLKNRLAMSPMCQYSATLEGEVTDWHLLHYPTRALGGVGLILVEATAVEP 63 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 P+ GI+S++ + K++ + G QL H GR + GG P+ Sbjct: 64 LGRISPYDLGIWSEDHLPGLKELARRIREAGAVPGIQLAHAGRKAGTARPWEGGKPLG-- 121 Query: 130 NKPISENRWRVLLPDGSHVK--YPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHG 187 WRV+ P YP P L+ + + R+++ + A A+RAGF IE+H Sbjct: 122 --------WRVVGPSPIPFDEGYPVPEPLDEAGMERILQAFVEGARRALRAGFQVIELHM 173 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLD 247 AHGYL+ FL N RTD YGGS+ NR RF QV + V +V R P + Sbjct: 174 AHGYLLSSFLSPLSNQRTDAYGGSLENRMRFPLQVAQAV------REVVPRELPLFVRVS 227 Query: 248 ATD 250 ATD Sbjct: 228 ATD 230 >3L5A-A nrPDB Length = 419 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 93/351 (26%), Positives = 138/351 (39%), Gaps = 47/351 (13%) Query: 23 LSHRVVLAPMT-RCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPGSAGFPHVPGIY 81 +S+R VL+PMT G A Y A+R+ G ++ + P F + I Sbjct: 39 ISNRFVLSPMTVNASTKEGYITKADLAYAARRSNSAGMQVTGAAYIEPYGKLFEYGFNID 98 Query: 82 SDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASH-------AVYQPNGGSPISSTNKPIS 134 D + + + G QL H GR S+ VY P SP++ + PI Sbjct: 99 HDACIPGLTNMASTMKQHGSLAIIQLAHAGRFSNQAILNFGKVYGP---SPMT-LHSPIE 154 Query: 135 ENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHGYLID 194 HV A+ +I +++ Y + L AI+AGFDG+EI A LI Sbjct: 155 ------------HVVI----AMSHEKINSIIQQYRDATLRAIKAGFDGVEISIAQRLLIQ 198 Query: 195 QFLKDGINDRTDQYGG-SIANRCRFLKQVVEGVVSAIGASK-----VGVRVSPAIDHLDA 248 F N RTD YG S+ NR R +V+ V I +G R +P + Sbjct: 199 TFFSTFSNRRTDHYGADSLKNRARLCLEVMRAVQEVIDKEAPDNFILGFRATPE----ET 254 Query: 249 TDSDPLSLGLAVVGMLNKLQG--VNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 SD LG + N+L ++ S + YL + H Y T + Sbjct: 255 RGSD---LGY-TIDEFNQLIDWVMDVSNIQYLAIASWGRHIYQNTSRTPGDHFGRPVNQI 310 Query: 307 KSLRMAYNGTFMSSGGFNK-ELGMQAVQQGDADLVSYGRLFIANPDLVSRF 356 +A ++SGG N E + A+Q AD+V F+ PD V + Sbjct: 311 VYEHLAGRIPLIASGGINSPESALDALQH--ADMVGMSSPFVTEPDFVHKL 359 >3K30-A nrPDB Length = 690 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 72/287 (25%), Positives = 128/287 (44%), Gaps = 28/287 (9%) Query: 80 IYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTNKPISENRWR 139 I+ D+ + A K++ +A+H GG +L H G +A Q + +P+ + P++ Sbjct: 82 IWDDQDLPALKRIADAIHEGGGLAGIELAHNG--MNAPNQLSRETPLGPGHLPVA----- 134 Query: 140 VLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHGYL-IDQFLK 198 PD + + RA+ +I + + + +I AG+D + ++GAHGY + FL Sbjct: 135 ---PD--TIAPIQARAMTKQDIDDLRRWHRNAVRRSIEAGYDIVYVYGAHGYSGVHHFLS 189 Query: 199 DGINDRTDQYGGSIANRCRFLKQVVEGVV-SAIGASKVGVRVSPAIDHLDATDSDPLSLG 257 N RTD+YGGS+ NR R L++++E + G + V R++ + + + Sbjct: 190 KRYNQRTDEYGGSLENRMRLLRELLEDTLDECAGRAAVACRITVEEEIDGGITREDIEGV 249 Query: 258 LAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSLRMAYNGTF 317 L +G L L VT R+ G+ E + + L+ Sbjct: 250 LRELGELPDLWDFAMGSWEGDSVTS-RFAPEGRQE-----------EFVAGLKKLTTKPV 297 Query: 318 MSSGGFNKELGM-QAVQQGDADLVSYGRLFIANPDLVSRFKIDGELN 363 + G F M + ++ G DL+ R IA+P L ++ + DG LN Sbjct: 298 VGVGRFTSPDAMVRQIKAGILDLIGAARPSIADPFLPNKIR-DGRLN 343 >2TMD-A nrPDB Length = 729 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 14/153 (9%) Query: 80 IYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTNKPISENRWR 139 I+ + V K + + VH G +LW+ G +HA PN + S P +++ Sbjct: 77 IWDEGDVRNLKAMTDEVHKYGALAGVELWYGG--AHA---PN----MESRATPRGPSQYA 127 Query: 140 VLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHGYLIDQFLKD 199 S+ K ++ S+I +V + Y +A + AGFD + ++GAH YL QFL Sbjct: 128 SEFETLSYCK-----EMDLSDIAQVQQFYVDAAKRSRDAGFDIVYVYGAHSYLPLQFLNP 182 Query: 200 GINDRTDQYGGSIANRCRFLKQVVEGVVSAIGA 232 N RTD+YGGS+ NR RF + +E V A+G+ Sbjct: 183 YYNKRTDKYGGSLENRARFWLETLEKVKHAVGS 215 >4LT6-A nrPDB Length = 514 Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 18/116 (15%) Query: 163 RVVEDYCLSALNAIRAGFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQV 222 R VED + + I+ FDGIEI L Q + D ++ R D S+ RC Sbjct: 152 RAVED---AFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRC------ 202 Query: 223 VEGVVSAIGASKVGVRVSPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYL 278 + ++ G RV+ I HL + + L L V + K +G+ + L +L Sbjct: 203 ----IRSLN----GCRVTDEILHL-VPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 249 >6D8Z-A nrPDB Length = 319 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 17/95 (17%) Query: 131 KPISE-NRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCL------SALNAIR-AGFDG 182 KP+ ++++LL D +KY K +L+ SE+ R VE C+ +N R GFDG Sbjct: 143 KPVQRIMKYQLLLKD--FLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDG 200 Query: 183 IEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCR 217 + L D FL TDQ G + RCR Sbjct: 201 KIVAQGKLLLQDTFLV------TDQDAGLLP-RCR 228 >5GJL-A nrPDB Length = 98 Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 9/70 (12%) Query: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCL---SALNAIR 177 NG SP+++ + I + +V PDG+ V + R +++ +++E YC ++ A+R Sbjct: 11 NGSSPVNNQGEHI---QVKVRSPDGAEVFFKIKRK---TKLEKLMEVYCNRLGQSMEAVR 64 Query: 178 AGFDGIEIHG 187 +DG IHG Sbjct: 65 FLYDGDRIHG 74 >5G6R-A nrPDB Length = 295 Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 5/62 (8%) Query: 33 TRCRALNGVPNAA--LAEYYAQRTTPGGFLISEGTMVSPGSAGFPHVPGIYSDEQVEAWK 90 T NG PN A LA++ T+ G I G M P G PH +YS E +E ++ Sbjct: 87 TIVNLTNGTPNQARKLADFV---TSHGARYIHGGIMAVPTMIGSPHAVLLYSGESLELFQ 143 Query: 91 QV 92 + Sbjct: 144 SI 145 >3GOC-A nrPDB Length = 237 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 8/62 (12%) Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHV------GRA 113 +++E T V G FP+VPG+ + ++ ++A+ G I C + V G A Sbjct: 70 VVAEATAV--GEVSFPYVPGLLAFREIPTVLAALDALPCPPGLIVCDGYGVAHPRRFGLA 127 Query: 114 SH 115 SH Sbjct: 128 SH 129 >3ZE8-A nrPDB Length = 283 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 180 FDGIEIHGAHGYLIDQF-LKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVR 238 D I+ +G G L + + D T +G +I C +L + EGV+SA KVG R Sbjct: 174 LDAIKKNGLEGGLAEVVKVLDSDGRPTPFFGRNIHENCPYLDKYDEGVMSATFTDKVGCR 233 >5JSK-A nrPDB Length = 317 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 173 LNAIRAGFDGIEIHGAHGYLIDQF-LKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIG 231 + + D I+ +G G L + + D T +G +I C +L + EGV+SA Sbjct: 201 VGTVVLALDAIKKNGLEGGLAEVVKVLDSDGRPTPFFGRNIHENCPYLDKYDEGVMSATF 260 Query: 232 ASKVGVR 238 KVG R Sbjct: 261 TDKVGCR 267 >5EGJ-A nrPDB Length = 179 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 1/30 (3%) Query: 61 ISEGTMVSPGSAGFP-HVPGIYSDEQVEAW 89 +S T V+ G P HVPG+Y ++ VE W Sbjct: 116 LSYLTFVALDDEGKPKHVPGVYPEDDVEKW 145 >4PEY-A nrPDB Length = 561 Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 19/26 (73%) Query: 353 VSRFKIDGELNKYNRKTFYTQDPVVG 378 ++ KIDGE+ Y+++ +YT+D VG Sbjct: 158 IADSKIDGEVGPYSQQQWYTRDSSVG 183 >6CI2-A nrPDB Length = 192 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 10/19 (52%), Positives = 15/19 (78%) Query: 339 LVSYGRLFIANPDLVSRFK 357 ++SYG +I +PD+V RFK Sbjct: 44 IISYGYRYIIHPDIVERFK 62 >6CI4-A nrPDB Length = 217 Score = 28.1 bits (61), Expect = 6.8, Method: Compositional matrix adjust. Identities = 10/19 (52%), Positives = 15/19 (78%) Query: 339 LVSYGRLFIANPDLVSRFK 357 ++SYG +I +PD+V RFK Sbjct: 69 IISYGYRYIIHPDIVERFK 87 >3I6D-A nrPDB Length = 470 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 19/104 (18%) Query: 246 LDATDSDPLSLGLAVVGMLNKLQGVNG----SKLAYLHVTQPRYHAYGQTESGRQGSDEE 301 +D +D+D +++ V+ L K+ +NG + + H + P+YH G + Sbjct: 376 VDLSDNDIINI---VLEDLKKVMNINGEPEMTCVTRWHESMPQYHV---------GHKQR 423 Query: 302 EAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDA---DLVSY 342 +L ++L AY G +M+ F + QG A D ++Y Sbjct: 424 IKELREALASAYPGVYMTGASFEGVGIPDCIDQGKAAVSDALTY 467 >5UPU-A nrPDB Length = 407 Score = 27.7 bits (60), Expect = 9.0, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Query: 167 DYCLSALNAIRAGFDGIEIHGAHGY---LIDQF--LKDGINDRTDQYGGSIANR 215 D + A+ + AG D + + AH + ++D LK + DR + GG++A R Sbjct: 142 DAWVRAMMLVDAGVDVLVVDTAHAHNRLVLDMVGKLKSEVGDRVEVVGGNVATR 195 >1ECX-A nrPDB Length = 384 Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Query: 168 YCLSALNAIRAGFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVV 227 + L L A F + HG G I +++ G+ R +GG R Q V G+V Sbjct: 187 FSLEKLEVDYASFSAHKFHGPKGVGI-TYIRKGVPIRPLIHGGGQERGLRSGTQNVPGIV 245 Query: 228 SAIGASKVGV-RVSPAIDHLDATDSDPLSLGLAVVG 262 A A ++ V +S A H++ S +S GL +G Sbjct: 246 GAARAMEIAVEELSEAAKHMEKLRSKLVS-GLMNLG 280 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2G5W-A nrPDB 565 e-161 2HS8-A nrPDB 533 e-152 5DXY-A nrPDB 510 e-145 2Q3R-A nrPDB 483 e-137 1ICQ-A nrPDB 475 e-134 3GX9-A nrPDB 447 e-126 5V4P-A nrPDB 422 e-118 4GBU-A nrPDB 418 e-117 4JIP-A nrPDB 416 e-117 4AWT-A nrPDB 412 e-116 5EPD-A nrPDB 412 e-115 4AEO-A nrPDB 412 e-115 3WJS-A nrPDB 410 e-115 6GI9-A nrPDB 410 e-115 4QNW-A nrPDB 409 e-115 4A3U-A nrPDB 402 e-112 3GKA-A nrPDB 397 e-111 4TMB-A nrPDB 387 e-108 5K1Q-A nrPDB 378 e-105 4QAI-A nrPDB 372 e-103 4E2D-A nrPDB 369 e-102 4RNU-A nrPDB 333 8e-92 3KRZ-A nrPDB 318 3e-87 3GR7-A nrPDB 305 2e-83 1Z48-A nrPDB 304 3e-83 5CPN-A nrPDB 304 5e-83 5OCS-A nrPDB 284 4e-77 1PS9-A nrPDB 273 9e-74 4RNX-A nrPDB 267 6e-72 3L5A-A nrPDB 261 3e-70 3HF3-A nrPDB 259 1e-69 3K30-A nrPDB 244 4e-65 2TMD-A nrPDB 217 7e-57 Sequences not found previously or not previously below threshold: 1VC4-A nrPDB 33 0.28 4BF9-A nrPDB 32 0.35 6BYC-A nrPDB 32 0.51 2IBG-E nrPDB 32 0.66 3BHF-A nrPDB 31 0.77 1OK6-A nrPDB 31 0.95 2WG3-A nrPDB 31 0.98 3N1G-B nrPDB 31 1.1 5OTA-A nrPDB 30 1.2 1Y0E-A nrPDB 30 1.4 3O15-A nrPDB 30 1.4 4U3W-A nrPDB 30 1.5 4B3J-A nrPDB 30 1.8 3L1R-A nrPDB 29 2.7 3K7I-B nrPDB 29 2.7 2BAA-A nrPDB 29 2.7 3IWR-A nrPDB 29 2.8 6DVI-A nrPDB 29 3.4 6DMY-B nrPDB 29 3.9 4DYG-A nrPDB 28 5.8 3F4N-A nrPDB 28 5.9 2Z1Q-A nrPDB 28 6.8 CONVERGED! >2G5W-A nrPDB Length = 391 Score = 565 bits (1456), Expect = e-161, Method: Composition-based stats. Identities = 391/391 (100%), Positives = 391/391 (100%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL Sbjct: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP Sbjct: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 Query: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF Sbjct: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 Query: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS Sbjct: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE Sbjct: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG Sbjct: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 Query: 361 ELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 ELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL Sbjct: 361 ELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 >2HS8-A nrPDB Length = 402 Score = 533 bits (1374), Expect = e-152, Method: Composition-based stats. Identities = 294/397 (74%), Positives = 336/397 (84%), Gaps = 7/397 (1%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 M ++ + N LFS YKMG+F+LSHRVVLAPMTRCRALN +P AAL EYY QR T GGFL Sbjct: 7 MASSAQDGNNPLFSPYKMGKFNLSHRVVLAPMTRCRALNNIPQAALGEYYEQRATAGGFL 66 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 I+EGTM+SP SAGFPHVPGI++ EQV WK++V+ VHAKG IFCQLWHVGRASH VYQP Sbjct: 67 ITEGTMISPTSAGFPHVPGIFTKEQVREWKKIVDVVHAKGAVIFCQLWHVGRASHEVYQP 126 Query: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 G +PISST KPIS NRWR+L+PDG+H YPKPRA+ EI +VVEDY SALNAI AGF Sbjct: 127 AGAAPISSTEKPIS-NRWRILMPDGTHGIYPKPRAIGTYEISQVVEDYRRSALNAIEAGF 185 Query: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 DGIEIHGAHGYLIDQFLKDGINDRTD+YGGS+ANRC+F+ QVV+ VVSAIGA +VGVRVS Sbjct: 186 DGIEIHGAHGYLIDQFLKDGINDRTDEYGGSLANRCKFITQVVQAVVSAIGADRVGVRVS 245 Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 PAIDHLDA DS+PLSLGLAVV LNK+Q +GSKLAYLHVTQPRY AYGQTE+GR GS+E Sbjct: 246 PAIDHLDAMDSNPLSLGLAVVERLNKIQLHSGSKLAYLHVTQPRYVAYGQTEAGRLGSEE 305 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 EEA+LM++LR AY GTF+ SGG+ +ELG++AV QGDADLVSYGRLFI+NPDLV R K++ Sbjct: 306 EEARLMRTLRNAYQGTFICSGGYTRELGIEAVAQGDADLVSYGRLFISNPDLVMRIKLNA 365 Query: 361 ELNKYNRKTFYTQDPVVGYTDYPFL------APFSRL 391 LNK+NRKTFYTQDPVVGYTDYPFL P SRL Sbjct: 366 PLNKFNRKTFYTQDPVVGYTDYPFLQGNGSNGPLSRL 402 >5DXY-A nrPDB Length = 387 Score = 510 bits (1314), Expect = e-145, Method: Composition-based stats. Identities = 259/379 (68%), Positives = 314/379 (82%), Gaps = 3/379 (0%) Query: 9 NETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVS 68 TLFS+YKMG+F+LSHRVVLAP+TRCRA+N +PN AL EYY QR+T GGFLI+EGTM+S Sbjct: 4 KPTLFSAYKMGKFNLSHRVVLAPLTRCRAINAIPNEALVEYYRQRSTAGGFLITEGTMIS 63 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 P SAGFPHVPGI++ EQVE WK+VV+A H +G IFCQLWHVGRASH VYQP G +PISS Sbjct: 64 PSSAGFPHVPGIFTKEQVEGWKKVVDAAHKEGAVIFCQLWHVGRASHQVYQPGGAAPISS 123 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 T+KPIS +W +LLPD ++ YP+PR L A+EI VVEDY ++A+NAI AGFDGIEIHGA Sbjct: 124 TSKPIS-KKWEILLPDATYGTYPEPRPLAANEILEVVEDYRVAAINAIEAGFDGIEIHGA 182 Query: 189 HGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDA 248 HGYL+DQF+KDGINDRTD+YGGS+ NRC+F+ QVV+ V +AIG +VG+R+SPAIDH DA Sbjct: 183 HGYLLDQFMKDGINDRTDEYGGSLENRCKFILQVVQAVSAAIGTDRVGIRISPAIDHTDA 242 Query: 249 TDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYH--AYGQTESGRQGSDEEEAKLM 306 DSDP SLGLAV+ LNKLQ GS+LAYLHVTQPRY +GQTE+G GS+EE A+LM Sbjct: 243 MDSDPRSLGLAVIERLNKLQFKLGSRLAYLHVTQPRYTADGHGQTEAGANGSEEEVAQLM 302 Query: 307 KSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYN 366 K+ R AY GTF+ GG+ +ELG+QAV QGDADLV++GR F++NPDLV R K++ LN+Y+ Sbjct: 303 KTWRGAYVGTFICCGGYTRELGLQAVAQGDADLVAFGRYFVSNPDLVLRLKLNAPLNRYD 362 Query: 367 RKTFYTQDPVVGYTDYPFL 385 R TFYT DPVVGYTDYP L Sbjct: 363 RATFYTHDPVVGYTDYPSL 381 >2Q3R-A nrPDB Length = 372 Score = 483 bits (1243), Expect = e-137, Method: Composition-based stats. Identities = 192/385 (49%), Positives = 259/385 (67%), Gaps = 17/385 (4%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFL 60 M + + L + YKMGRF+LSHRVVLAP+TR R+ VP A YY+QRTTPGGFL Sbjct: 1 MENGEAKQSVPLLTPYKMGRFNLSHRVVLAPLTRQRSYGNVPQPHAAIYYSQRTTPGGFL 60 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP 120 I+E T VS + G+ PGI++ E VEAWK +V+AVHAKGG FCQ+WHVGR S++ +QP Sbjct: 61 ITEATGVSDTAQGYQDTPGIWTKEHVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNSGFQP 120 Query: 121 NGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGF 180 NG +PIS ++KP+ + + + PR L EIP +V D+ L+A NA+ AGF Sbjct: 121 NGKAPISCSDKPLMPQIRSNGIDEA---LFTPPRRLGIEEIPGIVNDFRLAARNAMEAGF 177 Query: 181 DGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVS 240 DG+EIHGA+GYLIDQF+KD +NDRTD+YGGS+ NRC+F ++V+ V IG +VG+R+S Sbjct: 178 DGVEIHGANGYLIDQFMKDTVNDRTDEYGGSLQNRCKFPLEIVDAVAKEIGPDRVGIRLS 237 Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 P D++++ D++P +LGL + LNK + Y HV + R G+ + Sbjct: 238 PFADYMESGDTNPGALGLYMAESLNKY------GILYCHVIEARMKTMGEVHAC------ 285 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDG 360 + +R A+ GTF+S+GGF +E G +AV +G DLV+YGR F+ANPDL RF++D Sbjct: 286 --PHTLMPMRKAFKGTFISAGGFTREDGNEAVSKGRTDLVAYGRWFLANPDLPKRFQVDA 343 Query: 361 ELNKYNRKTFYTQDPVVGYTDYPFL 385 LNKY+R TFYT DPVVGYTDYPFL Sbjct: 344 PLNKYDRPTFYTSDPVVGYTDYPFL 368 >1ICQ-A nrPDB Length = 376 Score = 475 bits (1223), Expect = e-134, Method: Composition-based stats. Identities = 187/376 (49%), Positives = 258/376 (68%), Gaps = 19/376 (5%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPG 70 L S KMG+F+L HRVVLAP+TR R+ +P +Y+QR+T GG LI E T++S Sbjct: 15 PLMSPCKMGKFELCHRVVLAPLTRQRSYGYIPQPHAILHYSQRSTNGGLLIGEATVISET 74 Query: 71 SAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTN 130 G+ VPGI++ EQVEAWK +V+AVHAKGG FCQ+WHVGR S+ +QPNG PIS T+ Sbjct: 75 GIGYKDVPGIWTKEQVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNKDFQPNGEDPISCTD 134 Query: 131 KPISENRWRVLLPDGSHVKY-PKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAH 189 + ++ ++ +G + + +PR L EIP++V ++ ++A NAI AGFDG+EIHGAH Sbjct: 135 RGLTPQ----IMSNGIDIAHFTRPRRLTTDEIPQIVNEFRVAARNAIEAGFDGVEIHGAH 190 Query: 190 GYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDAT 249 GYLIDQF+KD +NDR+D+YGGS+ NRCRF ++VE V + IG+ +VG+R+SP + +A Sbjct: 191 GYLIDQFMKDQVNDRSDKYGGSLENRCRFALEIVEAVANEIGSDRVGIRISPFAHYNEAG 250 Query: 250 DSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSL 309 D++P +LGL +V LNK LAY HV +PR E + + + Sbjct: 251 DTNPTALGLYMVESLNKYD------LAYCHVVEPRMKT--------AWEKIECTESLVPM 296 Query: 310 RMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYNRKT 369 R AY GTF+ +GG+++E G +A+ + ADLV+YGRLFI+NPDL RF+++ LNKYNR T Sbjct: 297 RKAYKGTFIVAGGYDREDGNRALIEDRADLVAYGRLFISNPDLPKRFELNAPLNKYNRDT 356 Query: 370 FYTQDPVVGYTDYPFL 385 FYT DP+VGYTDYPFL Sbjct: 357 FYTSDPIVGYTDYPFL 372 >3GX9-A nrPDB Length = 377 Score = 447 bits (1150), Expect = e-126, Method: Composition-based stats. Identities = 154/380 (40%), Positives = 211/380 (55%), Gaps = 19/380 (5%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMV 67 SN LF+ ++G L +RV++AP+TR R + VP YY QR + G +ISE T + Sbjct: 7 SNPGLFTPLQLGSLSLPNRVIMAPLTRSRTPDSVPGRLQQIYYGQRAS-AGLIISEATNI 65 Query: 68 SPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPIS 127 SP + G+ + PGI++D Q WK VVEAVHAKGG I QLWHVGR SH + QP+G P++ Sbjct: 66 SPTARGYVYTPGIWTDAQEAGWKGVVEAVHAKGGRIALQLWHVGRVSHELVQPDGQQPVA 125 Query: 128 STNKPISENRWRVLLPDGSHVKYPK--PRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 + V DG+ +P PRALE EIP +VEDY +A A RAGFD +E+ Sbjct: 126 PSALKAEGAECFVEFEDGTAGLHPTSTPRALETDEIPGIVEDYRQAAQRAKRAGFDMVEV 185 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 H A L +QFL G N RTDQYGGSI NR RF +VV+ V G +VG+R++P ++ Sbjct: 186 HAAAACLPNQFLATGTNRRTDQYGGSIENRARFPLEVVDAVAEVFGPERVGIRLTPFLEL 245 Query: 246 LDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKL 305 TD +P ++ + G L++ LAYLH +P + G Sbjct: 246 FGLTDDEPEAMAFYLAGELDR------RGLAYLHFNEPDWIG---------GDITYPEGF 290 Query: 306 MKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKY 365 + +R + G + G ++ + AD V++GR FIANPDL RF++ LN+ Sbjct: 291 REQMRQRFKGGLIYCGNYDAGRAQARLDDNTADAVAFGRPFIANPDLPERFRLGAALNEP 350 Query: 366 NRKTFYTQDPVVGYTDYPFL 385 + TFY VGYTDYPFL Sbjct: 351 DPSTFYG-GAEVGYTDYPFL 369 >5V4P-A nrPDB Length = 400 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 137/386 (35%), Positives = 207/386 (53%), Gaps = 23/386 (5%) Query: 9 NETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALAE-YYAQRTT-PGGFLISEG 64 + LF K+G L+HR V+ P+TR RA + +PN A YY QR PG +I+EG Sbjct: 14 DTNLFEPIKIGNTQLAHRAVMPPLTRMRATHPGNIPNKEWAAVYYGQRAQRPGTMIITEG 73 Query: 65 TMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQP-NGG 123 T +SP + G+ + PGI+SDEQV WK + A+H F + QLW +G AS +G Sbjct: 74 TFISPQAGGYDNAPGIWSDEQVAEWKNIFLAIHDCQSFAWVQLWSLGWASFPDVLARDGL 133 Query: 124 SPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGI 183 ++++ + D +++++ +L +I + ++DY +A N+I AG DG+ Sbjct: 134 RYDCASDRVYMNATLQEKAKDANNLEH----SLTKDDIKQYIKDYIHAAKNSIAAGADGV 189 Query: 184 EIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAI 243 EIH A+GYL++QFL N RTD+YGG+I NR RF +VV+ ++ IG +VG+R+SP Sbjct: 190 EIHSANGYLLNQFLDPHSNKRTDEYGGTIENRARFTLEVVDALIETIGPERVGLRLSPYG 249 Query: 244 DHL---DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 + ++ V+G L K + G +LA++H+ +PR E G E Sbjct: 250 TFNSMSGGAEPGIIAQYSYVLGELEK-RAKAGKRLAFVHLVEPRVTDPSLVE----GEGE 304 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD---LVSYGRLFIANPDLVSRFK 357 + G + +G + L + V++ D L+ YGR FI+NPDLV R + Sbjct: 305 YSEGTNDFAYSIWKGPIIRAGNY--ALHPEVVREQVKDPRTLIGYGRFFISNPDLVYRLE 362 Query: 358 IDGELNKYNRKTFYTQDPVVGYTDYP 383 LNKY+R TFYT GYTDYP Sbjct: 363 EGLPLNKYDRSTFYT-MSAEGYTDYP 387 >4GBU-A nrPDB Length = 400 Score = 418 bits (1073), Expect = e-117, Method: Composition-based stats. Identities = 144/399 (36%), Positives = 212/399 (53%), Gaps = 25/399 (6%) Query: 4 AQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALA-EYYAQRTT-PGGF 59 A G++N LF K+G +L HR V+ P+TR RAL+ +PN A EYY QR PG Sbjct: 11 ALGDTN--LFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTM 68 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQ 119 +I+EG +SP + G+ + PG++S+EQ+ W ++ A+H K F++ QL +G A+ Sbjct: 69 IITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLAVLGWAAFPDNL 128 Query: 120 PNGGSPISSTNKPISENRWRVLLPDGSHVKYPKP-RALEASEIPRVVEDYCLSALNAIRA 178 G S S+N + + K P +L EI + +++Y +A N+I A Sbjct: 129 ARDGLRYDSA----SDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEYVQAAKNSIAA 184 Query: 179 GFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVR 238 G DG+EIH A+GYL++QFL N RTD+YGGSI NR RF +VV+ +V AIG KVG+R Sbjct: 185 GADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIENRARFTLEVVDALVEAIGHEKVGLR 244 Query: 239 VSPAIDHL---DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGR 295 +SP ++ ++ V G L K + G +LA++H+ +PR TE Sbjct: 245 LSPYGVFNSMSGGAETGIVAQYAYVAGELEK-RAKAGKRLAFVHLVEPRVTNPFLTEGEG 303 Query: 296 QGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD---LVSYGRLFIANPDL 352 + + + G + +G F L + V++ D L+ YGR FI+NPDL Sbjct: 304 EYEGGSN----DFVYSIWKGPVIRAGNF--ALHPEVVREEVKDKRTLIGYGRFFISNPDL 357 Query: 353 VSRFKIDGELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 V R + LNKY+R TFY Q GY DYP +L Sbjct: 358 VDRLEKGLPLNKYDRDTFY-QMSAHGYIDYPTYEEALKL 395 >4JIP-A nrPDB Length = 377 Score = 416 bits (1069), Expect = e-117, Method: Composition-based stats. Identities = 148/379 (39%), Positives = 213/379 (56%), Gaps = 10/379 (2%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSP 69 +LF + G L++R+V+AP+TR R+ +PN A YY QR T G +++EGT +S Sbjct: 2 TSLFEPAQAGDIALANRIVMAPLTRNRSPGAIPNNLNATYYEQRAT-AGLIVTEGTPISQ 60 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 G+ VPG+Y E +E WK++ + VH+ GG I Q+WHVGR SH QP+GG P++ + Sbjct: 61 QGQGYADVPGLYKREAIEGWKKITDGVHSAGGKIVAQIWHVGRISHTSLQPHGGQPVAPS 120 Query: 130 NKPISENRWRVLLP-DGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 + + G+ + +PRAL +I ++EDY A A+ AGFDG+EIH A Sbjct: 121 AITAKSKTYIINDDGTGAFAETSEPRALTIDDIGLILEDYRSGARAALEAGFDGVEIHAA 180 Query: 189 HGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDA 248 +GYLI+QFLK N RTD YGGSI NR RFL +VV+ V IGA + G+R+SP D Sbjct: 181 NGYLIEQFLKSSTNQRTDDYGGSIENRARFLLEVVDAVAEEIGAGRTGIRLSPVTPANDI 240 Query: 249 TDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKS 308 ++DP L VV L K LA++HV + + + + Sbjct: 241 FEADPQPLYNYVVEQLGK------RNLAFIHVVEGATGGP-RDFKQGDKPFDYASFKAAY 293 Query: 309 LRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYNRK 368 G ++++ G++++ ++AV+ G D V++G+ FIANPDLV R K D LN N+ Sbjct: 294 RNAGGKGLWIANNGYDRQSAIEAVESGKVDAVAFGKAFIANPDLVRRLKNDAPLNAPNQP 353 Query: 369 TFYTQDPVVGYTDYPFLAP 387 TFY GYTDYP LA Sbjct: 354 TFYGGG-AEGYTDYPALAQ 371 >4AWT-A nrPDB Length = 365 Score = 412 bits (1060), Expect = e-116, Method: Composition-based stats. Identities = 149/378 (39%), Positives = 214/378 (56%), Gaps = 23/378 (6%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALAEYYAQRTTPGGFLISEGTMV 67 ++LF +G L +R+V+ P+TR RA V N +A YYAQR + G ++SEGT + Sbjct: 3 QSLFQPITLGALTLKNRIVMPPLTRSRASQPGDVANHMMAIYYAQRAS-AGLIVSEGTQI 61 Query: 68 SPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPIS 127 SP + G+ PGIY+ EQ+ W+ V EAVHAKG IF QLWHVGR +H +G PIS Sbjct: 62 SPTAKGYAWTPGIYTPEQIAGWRIVTEAVHAKGCAIFAQLWHVGRVTHPDN-IDGQQPIS 120 Query: 128 STNKPISENRWRVL--LPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 S+ + V + V PRA+ ++I +V+ DY +ALNA+ AGFDGIE+ Sbjct: 121 SSTLKAENVKVFVDNGSDEPGFVDVAVPRAMTKADIAQVIADYRQAALNAMEAGFDGIEL 180 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 H A+GYLI+QF+ N+R+D+YGGS+ NR RFL +VV +V AIGA +VGVR++P Sbjct: 181 HAANGYLINQFIDSEANNRSDEYGGSLENRLRFLDEVVAALVDAIGAERVGVRLAPLTTL 240 Query: 246 LDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKL 305 D+DP+ A +LNK ++ YLH+ + + + + Sbjct: 241 NGTVDADPILTYTAAAALLNK------HRIVYLHIAEVDW----------DDAPDTPVSF 284 Query: 306 MKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKY 365 ++LR AY G + +G +N E QA+ G AD++ +GR FIANPDL R + L ++ Sbjct: 285 KRALREAYQGVLIYAGRYNAEKAEQAINDGLADMIGFGRPFIANPDLPERLRHGYPLAEH 344 Query: 366 NRKTFYTQDPVVGYTDYP 383 T + G TDYP Sbjct: 345 VPATLFGGGE-KGLTDYP 361 >5EPD-A nrPDB Length = 385 Score = 412 bits (1060), Expect = e-115, Method: Composition-based stats. Identities = 149/381 (39%), Positives = 211/381 (55%), Gaps = 23/381 (6%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGFLISEGTM 66 + TLF +G L++R+V+AP+TR RA G VP A YYAQR + G +ISE T Sbjct: 22 TKTTLFQPTSLGAITLANRIVMAPLTRNRAGAGFVPGELTAGYYAQRAS-AGLIISEATQ 80 Query: 67 VSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPI 126 +S G+ PGIY+ Q++ WK+V AVH KGG I QLWHVGR SH QPNGG+P+ Sbjct: 81 ISQQGQGYQDTPGIYTQAQIDGWKKVTAAVHKKGGRIVLQLWHVGRISHVNLQPNGGAPV 140 Query: 127 SSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIH 186 + + + + V +PRALE E+ +V+D+ +A N+I AGFDG+E+H Sbjct: 141 APSAIRAEVKTFV----NNGFVDVSEPRALELEELAGIVDDFRKAAANSIEAGFDGVEVH 196 Query: 187 GAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHL 246 GA+GYL++QF KDG N RTD YGGS+ NR R + +V V IG + G+R+SP Sbjct: 197 GANGYLLEQFAKDGANMRTDTYGGSVENRARLMLEVTAAVAQEIGPERTGIRISPVSPAN 256 Query: 247 DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 + SDP + +V L+ L +AY+HV + G + Sbjct: 257 GISCSDPQTQYDYIVDKLDAL------GIAYIHVVE----------GATGGPRDVAPFDY 300 Query: 307 KSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYN 366 SLR ++ T++++ GF+ EL + G ADL+++GR FIANPDLV R + L + N Sbjct: 301 GSLRRRFSRTYIANNGFDLELATSHLADGRADLIAFGRPFIANPDLVERLQSGAPLAEVN 360 Query: 367 RKTFYTQDPVVGYTDYPFLAP 387 + GYTDYP + Sbjct: 361 AAKIFG-GSAAGYTDYPRFSE 380 >4AEO-A nrPDB Length = 362 Score = 412 bits (1059), Expect = e-115, Method: Composition-based stats. Identities = 158/383 (41%), Positives = 212/383 (55%), Gaps = 30/383 (7%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGFLISEGTMVS 68 TLF K+G L +R+++AP+TRCRA G VPNA +AEYY QR + G ++SE T VS Sbjct: 2 TTLFDPIKLGDLQLPNRIIMAPLTRCRADEGRVPNALMAEYYVQRAS-AGLILSEATSVS 60 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 P G+P PGI++DEQV W V +AVHA GG IF QLWHVGR SH Y NG P++ Sbjct: 61 PMGVGYPDTPGIWNDEQVRGWNNVTKAVHAAGGRIFLQLWHVGRISHPSYL-NGELPVAP 119 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 + + V YP PRALE EI +VE Y A NA AGFDG+EIHGA Sbjct: 120 SAIQPKGHVSLVRPLS----DYPTPRALETEEINDIVEAYRSGAENAKAAGFDGVEIHGA 175 Query: 189 HGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDA 248 +GYL+DQFL+ N RTD+YGGS+ NR R L +V + + GA +VGV ++P D D Sbjct: 176 NGYLLDQFLQSSTNQRTDRYGGSLENRARLLLEVTDAAIEVWGAQRVGVHLAPRADAHDM 235 Query: 249 TDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKS 308 D+D V L K +A++ + E + + Sbjct: 236 GDADRAETFTYVARELGK------RGIAFICSRE----------------READDSIGPL 273 Query: 309 LRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYNRK 368 ++ A+ G ++ + F+K A+ G AD V++G FIANPDL +R D LN+ + + Sbjct: 274 IKEAFGGPYIVNERFDKASANAALASGKADAVAFGVPFIANPDLPARLAADAPLNEAHPE 333 Query: 369 TFYTQDPVVGYTDYPFLAPFSRL 391 TFY + P VGY DYP L + L Sbjct: 334 TFYGKGP-VGYIDYPRLKLAAAL 355 >3WJS-A nrPDB Length = 361 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 152/378 (40%), Positives = 217/378 (57%), Gaps = 27/378 (7%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPGGFLISEGTMVS 68 TLF G +R+V++P+TR RA VP +AEYYAQR + G +I+E T +S Sbjct: 2 PTLFDPIDFGPIHAKNRIVMSPLTRGRADKEAVPTPIMAEYYAQRAS-AGLIITEATGIS 60 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 G+P PGI+SD QVEAWK +V VHAKGG I CQLWH+GR H+ G P+SS Sbjct: 61 REGLGWPFAPGIWSDAQVEAWKPIVAGVHAKGGKIVCQLWHMGRMVHSSV--TGTQPVSS 118 Query: 129 TNK--PISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIH 186 + P + + P + + RA++A++I R++ DY +A NAIRAGFDG++IH Sbjct: 119 SATTAPGEVHTYEGKKP------FEQARAIDAADISRILNDYENAARNAIRAGFDGVQIH 172 Query: 187 GAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHL 246 A+GYLID+FL++G N RTD+YGG NR RFLK+V E V++AIGA + GVR+SP D Sbjct: 173 AANGYLIDEFLRNGTNHRTDEYGGVPENRIRFLKEVTERVIAAIGADRTGVRLSPNGDTQ 232 Query: 247 DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 DS P ++ + +L L +A+L + +P + ++ KL Sbjct: 233 GCIDSAPETVFVPAAKLLQDL------GVAWLELREPGPNG--------TFGKTDQPKLS 278 Query: 307 KSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYN 366 +R + + + + E A+ +G AD +++GR FI+NPDL RF L + Sbjct: 279 PQIRKVFLRPLVLNQDYTFEAAQTALAEGKADAIAFGRKFISNPDLPERFARGIALQPDD 338 Query: 367 RKTFYTQDPVVGYTDYPF 384 KT+Y+Q P GYTDYP Sbjct: 339 MKTWYSQGP-EGYTDYPS 355 >6GI9-A nrPDB Length = 373 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 141/381 (37%), Positives = 206/381 (54%), Gaps = 20/381 (5%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALAEYYAQRTTPGGFLISEGT 65 S E LF+ K+G +RV +AP+TR R++ +P + EYY QR + G +ISE T Sbjct: 2 SAEKLFTPLKVGAVTAPNRVFMAPLTRLRSIEPGDIPTPLMGEYYRQRAS-AGLIISEAT 60 Query: 66 MVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSP 125 +S + G+ PG++S EQ+ AWK++ VHA+ G I QLWH GR SH+ QP G +P Sbjct: 61 QISAQAKGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQLWHTGRLSHSSIQPGGQAP 120 Query: 126 ISSTNKPISENR-WRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 +S++ + R + V PRALE EIP +V D+ + NA AGFD +E Sbjct: 121 VSASALNANTRTSLRDENGNAIRVDTTTPRALELDEIPGIVNDFRQAVANAREAGFDLVE 180 Query: 185 IHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAID 244 +H AHGYL+ QFL N RTDQYGGS+ NR R + +VV+ V + A ++G+RVSP I Sbjct: 181 LHSAHGYLLHQFLSPSSNQRTDQYGGSVENRARLVLEVVDAVCNEWSADRIGIRVSP-IG 239 Query: 245 HLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAK 304 D+ P A L ++ + +AYLH+ +E+ G Sbjct: 240 TFQNVDNGPNEEADA----LYLIEELAKRGIAYLHM----------SETDLAGGKPYSEA 285 Query: 305 LMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNK 364 + +R ++G + +G + E + +G D V++GR +IANPDLV+R + ELN Sbjct: 286 FRQKVRERFHGVIIGAGAYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAELNP 345 Query: 365 YNRKTFYTQDPVVGYTDYPFL 385 ++FY GYTDYP L Sbjct: 346 QRPESFYGGG-AEGYTDYPSL 365 >4QNW-A nrPDB Length = 392 Score = 409 bits (1052), Expect = e-115, Method: Composition-based stats. Identities = 146/392 (37%), Positives = 211/392 (53%), Gaps = 34/392 (8%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRAL-NGVPNAALAEYYAQRTT-PGGFLISEGT 65 S+ LF K+GR L HR+++AP TR RA GVP + EYY QR + PG LI+E T Sbjct: 6 SSAQLFKPLKVGRCHLQHRMIMAPTTRFRADGQGVPLPFVQEYYGQRASVPGTLLITEAT 65 Query: 66 MVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSP 125 ++P + G+ HVPGI+S+ Q EAW+++V VH+K FIFCQLW GRA+ + Sbjct: 66 DITPKAMGYKHVPGIWSEPQREAWREIVSRVHSKKCFIFCQLWATGRAADPDVLADMKDL 125 Query: 126 ISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 ISS+ P+ E P PRAL EI + + D+ +A NAI AGFDG+EI Sbjct: 126 ISSSAVPVEEKG-------------PLPRALTEDEIQQCIADFAQAARNAINAGFDGVEI 172 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 HGA+GYLIDQF + N R D++GGSI NR RF +V V+ A+GA +VGV++SP + Sbjct: 173 HGANGYLIDQFTQKSCNHRQDRWGGSIENRARFAVEVTRAVIEAVGADRVGVKLSPYSQY 232 Query: 246 LDATDSDPLSLGL-AVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAK 304 L D L ++ + +L +AYLH+ R+ + + D Sbjct: 233 LGMGTMDELVPQFEYLIAQMRRLD------VAYLHLANSRW-----LDEEKPHPDPNHEV 281 Query: 305 LMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD-----LVSYGRLFIANPDLVSRFKID 359 ++ + + +GG++ + +Q A +++GR FI+ PDL R Sbjct: 282 FVRV--WGQSSPILLAGGYDAASAEKVTEQMAAATYTNVAIAFGRYFISTPDLPFRVMAG 339 Query: 360 GELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 +L KY+R +FY+ GY DYPF A + L Sbjct: 340 IQLQKYDRASFYSTLSREGYLDYPFSAEYMAL 371 >4A3U-A nrPDB Length = 358 Score = 402 bits (1033), Expect = e-112, Method: Composition-based stats. Identities = 143/381 (37%), Positives = 207/381 (54%), Gaps = 27/381 (7%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRAL-NGVPNAALAEYYAQRTTPGGFLISEGTMVS 68 +LF + G F +R+ +AP+TR RA + VP +AEYYAQR + G +ISE T +S Sbjct: 2 PSLFDPIRFGAFTAKNRIWMAPLTRGRATRDHVPTEIMAEYYAQRAS-AGLIISEATGIS 60 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 G+P+ PGI+SD QVEAW + +AVH GG IF QLWH+GR + +G P++ Sbjct: 61 QEGLGWPYAPGIWSDAQVEAWLPITQAVHDAGGLIFAQLWHMGRMVPSNV--SGMQPVAP 118 Query: 129 TN--KPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIH 186 + P + + P Y RAL EIPR+++DY +A +A++AGFDG++IH Sbjct: 119 SASQAPGLGHTYDGKKP------YDVARALRLDEIPRLLDDYEKAARHALKAGFDGVQIH 172 Query: 187 GAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHL 246 A+GYLID+F++D N R D+YGG++ NR R LK V E V++ IG + VR+SP + Sbjct: 173 AANGYLIDEFIRDSTNHRHDEYGGAVENRIRLLKDVTERVIATIGKERTAVRLSPNGEIQ 232 Query: 247 DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 DS P + + ML+ L +A+L + + ++ KL Sbjct: 233 GTVDSHPEQVFIPAAKMLSDLD------IAFLGMREGAVDG--------TFGKTDQPKLS 278 Query: 307 KSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYN 366 +R + + + + E A+ G AD +S+GR FI NPDL RF L K Sbjct: 279 PEIRKVFKPPLVLNQDYTFETAQAALDSGVADAISFGRPFIGNPDLPRRFFEKAPLTKDV 338 Query: 367 RKTFYTQDPVVGYTDYPFLAP 387 +T+YTQ P GYTDYP L Sbjct: 339 IETWYTQTP-KGYTDYPLLGD 358 >3GKA-A nrPDB Length = 361 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 157/386 (40%), Positives = 217/386 (56%), Gaps = 30/386 (7%) Query: 1 MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGF 59 M + +LF +G L++R+++AP+TR RA + PNA +A YYA+R + G Sbjct: 1 MAHHHHHHMPSLFDPLTIGDLTLANRIIMAPLTRARAGDTRTPNALMARYYAERAS-AGL 59 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQ 119 +ISE T V+P G+ PGI+S EQV+ W+ V +AVHA GG IF QLWHVGR S V+ Sbjct: 60 IISEATSVTPQGVGYASTPGIWSPEQVDGWRLVTDAVHAAGGRIFLQLWHVGRVSDPVFL 119 Query: 120 PNGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAG 179 +G P++ + + V Y PRALE EIP VV + A NA AG Sbjct: 120 -DGALPVAPSAIAPGGHVSLVRPQR----PYVTPRALELDEIPGVVAAFRRGAENARAAG 174 Query: 180 FDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRV 239 FDG+E+HGA+GYL+DQFL+D N RTD YGGSI NR R L +VV+ + A++VGV + Sbjct: 175 FDGVEVHGANGYLLDQFLQDSANRRTDAYGGSIENRARLLLEVVDAAIDVWSAARVGVHL 234 Query: 240 SPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSD 299 +P D DSDP + V L + ++A+L + ++G G+Q Sbjct: 235 APRGDAHTMGDSDPAATFGHVARELGR------RRIAFLFARE----SFGGDAIGQQ--- 281 Query: 300 EEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKID 359 L+ A+ G F+ + F + A+ G AD V++G+LFIANPDL RFK++ Sbjct: 282 ---------LKAAFGGPFIVNENFTLDSAQAALDAGQADAVAWGKLFIANPDLPRRFKLN 332 Query: 360 GELNKYNRKTFYTQDPVVGYTDYPFL 385 LN+ N TFY Q VGYTDYP L Sbjct: 333 APLNEPNAATFYAQGE-VGYTDYPAL 357 >4TMB-A nrPDB Length = 403 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 136/392 (34%), Positives = 207/392 (52%), Gaps = 21/392 (5%) Query: 5 QGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRA--LNGVPNAALAE-YYAQRTT-PGGFL 60 G++N +F K+G +L HRVV+ +TR RA +PN AE YY QR+ PG + Sbjct: 11 LGDTN--IFKPIKIGNNELKHRVVMPALTRMRAIAPGNIPNTEWAEEYYRQRSQYPGTLI 68 Query: 61 ISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGR-ASHAVYQ 119 I+EGT S S G+P+VPGI+S EQ+ WK++ A+H F++ QLW +GR A V + Sbjct: 69 ITEGTFPSAQSGGYPNVPGIWSKEQLAEWKKIFNAIHENKSFVWVQLWVLGRQAWPEVLK 128 Query: 120 PNGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAG 179 G S+T+ + ++ ++ + EI + +++Y +A AI AG Sbjct: 129 KEGLRYDSATDDLYMGEEEKERALKANNPQHG----ITKEEIKQYIKEYVDAAKKAIDAG 184 Query: 180 FDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRV 239 DG++IH A+GYL++QFL N+RTD+YGGSI NR RF +VV+ VV A+GA + +R Sbjct: 185 ADGVQIHSANGYLLNQFLDPISNNRTDEYGGSIENRARFTLEVVDAVVDAVGAERTSIRF 244 Query: 240 SPA--IDHLDATDSDPLSLGL-AVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQ 296 SP + ++ + V+G L K + G +LA++ + +PR E + Sbjct: 245 SPYGTFGTMSGGENPGIVAQYAYVIGELEK-RARAGKRLAFIDLVEPRVTDPFLPEFEKW 303 Query: 297 GSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD-LVSYGRLFIANPDLVSR 355 + + + + G + G + + + + L+ YGR FIANPDLV R Sbjct: 304 FKEGTN----EFIYSIWKGPVLRVGNYALDPDQATLDSKKPNTLIGYGRSFIANPDLVYR 359 Query: 356 FKIDGELNKYNRKTFYTQDPVVGYTDYPFLAP 387 + LNKY+R TFYT GYTDYP Sbjct: 360 LEKGLPLNKYDRNTFYTFTK-EGYTDYPSYEE 390 >5K1Q-A nrPDB Length = 355 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 130/362 (35%), Positives = 197/362 (54%), Gaps = 24/362 (6%) Query: 7 NSNETLFSSYKMGR-FDLSHRVVLAPMTRCRALNG-VPNAALAEYYAQRTTPGGFLISEG 64 NS E LF +YK+ L +R+++AP+TRC A VP + YYA+R G +ISE Sbjct: 8 NSVENLFDTYKLNDTITLKNRILMAPLTRCMADANLVPTDDMVAYYARRA-EAGLIISEA 66 Query: 65 TMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGS 124 T++ P + G+P+ PGI++ Q+ W++V +AVHA GG IF QLWH GR +H + GG Sbjct: 67 TIIRPDAQGYPNTPGIFTQAQIAGWRKVTDAVHANGGKIFVQLWHTGRVAHPHFF-GGGD 125 Query: 125 PISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 ++ + + I + +P + Y P+A+ +I +V DY +A N I AGFDG+E Sbjct: 126 VLAPSAQKIEGS-----VPRMRELTYVTPKAVTVEDIQGLVRDYAKAAENVIEAGFDGVE 180 Query: 185 IHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAID 244 IHGA+GYLIDQFL N RTD+YGG+ N RF +VV+ +++ IG + G+R+SP Sbjct: 181 IHGANGYLIDQFLHHDSNRRTDEYGGTPVNMSRFALEVVDAIIARIGHDRTGLRISPGAY 240 Query: 245 HLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAK 304 A+DS + ++ L K LA++H+ G S Sbjct: 241 FNMASDSRDRVVFDYLLPELEK------RDLAFVHIGIFDDSIEFDYLGGTASS------ 288 Query: 305 LMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNK 364 +R Y T + G ++ E +A+ + DL++ GR FIANPD V++ + EL Sbjct: 289 ---YVRAHYGKTLVGVGSYSAETASKAIAEDKFDLIAIGRPFIANPDYVAKVRNSEELVA 345 Query: 365 YN 366 Y+ Sbjct: 346 YS 347 >4QAI-A nrPDB Length = 407 Score = 372 bits (956), Expect = e-103, Method: Composition-based stats. Identities = 128/383 (33%), Positives = 205/383 (53%), Gaps = 26/383 (6%) Query: 13 FSSYKMGRFDLSHRVVLAPMTRCRALN-GVPNAALAEYYAQRTT-PGGFLISEGTMVSPG 70 F S K+G L ++V P TR RAL P+ +YY R+T PG LI+E T VSP Sbjct: 15 FQSIKVGNNTLQTKIVYPPTTRFRALEDHTPSDLQLQYYGDRSTFPGTLLITEATFVSPQ 74 Query: 71 SAGFPHV-PGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHA-VYQPNGGSPISS 128 ++G+ PGI++D+ +AWK + + VHA G F+ QL +GR + V + G +P+S+ Sbjct: 75 ASGWEGAAPGIWTDKHAKAWKVITDKVHANGSFVSTQLIFLGRVADPAVMKTRGLNPVSA 134 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVV-EDYCLSALNAIRAGFDGIEIHG 187 + S+ G+ V RAL E+ +V E Y +A A+ AGFD IE+H Sbjct: 135 SATYESDAAKEAAEAVGNPV-----RALTTQEVKDLVYEAYTNAAQKAMDAGFDYIELHA 189 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLD 247 AHGYL+DQFL+ N RTD+YGGSI NR R + ++++ + + +GA K+G+R+SP + Sbjct: 190 AHGYLLDQFLQPCTNQRTDEYGGSIENRARLILELIDHLSTIVGADKIGIRISPWATFQN 249 Query: 248 AT----DSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEA 303 PL+ +V L + + G +AY+ V +PR S+E++A Sbjct: 250 MKAHKDTVHPLTTFSYLVHELQQ-RADKGQGIAYISVVEPRVSG------NVDVSEEDQA 302 Query: 304 KLMKSLRMAYNGTFMSSGGFNKELGM-QAVQQGDAD---LVSYGRLFIANPDLVSRFKID 359 + + + G + +G ++ + + +++ AD LV + R F +NP+LV + + Sbjct: 303 GDNEFVSKIWKGVILKAGNYSYDAPEFKTLKEDIADKRTLVGFSRYFTSNPNLVWKLRDG 362 Query: 360 GELNKYNRKTFYTQDPVVGYTDY 382 +L Y+R TFY+ D GY + Sbjct: 363 IDLVPYDRNTFYS-DNNYGYNTF 384 >4E2D-A nrPDB Length = 382 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 136/393 (34%), Positives = 210/393 (53%), Gaps = 37/393 (9%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVP-NAALAEYYAQRTTPGGFLISEG 64 + L K+GR+ L +R+++AP+TRC+A VP ++ +YY R + G +I+E Sbjct: 6 TFPELLRPLKLGRYTLRNRIIMAPLTRCQATEDGHVPRTESMLKYYEDRAS-AGLIIAEA 64 Query: 65 TMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRAS---------H 115 TMV P GF PGIYSD Q+E W+++V+AVH KGG IF QL H GRA Sbjct: 65 TMVQPNYTGFLTEPGIYSDAQIEEWRKIVDAVHKKGGLIFLQLIHAGRAGIPEKILQQPK 124 Query: 116 AVYQPNGGSPISSTNKPISENRWRVLL-PDGSHVKYPKPRALEASEIP-RVVEDYCLSAL 173 + P G ++++ PI ++R G Y P L E+ ++ + A Sbjct: 125 SDQDPLAGRLLAASAIPIKDHRIPAYFAASGEKETYGVPEELTDDEVRNGIIPLFVEGAK 184 Query: 174 NAI-RAGFDGIEIHGAHGYLIDQFLKDGINDR-TDQYGG-SIANRCRFLKQVVEGVVSAI 230 NAI +AGFDG+EIHGA+GYL+D F ++ N R + Y G +I RC+ + V + V A+ Sbjct: 185 NAIFKAGFDGVEIHGANGYLLDAFFRESSNKRQSGPYAGTTIDTRCQLIYDVTKSVCDAV 244 Query: 231 GASKVGVRVSPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQ 290 G+ +VG+R+SP DS+P +L + + L LAYLH + Sbjct: 245 GSDRVGLRISPLNGVHGMIDSNPEALTKHLCKKIEPL------SLAYLHYLRGDMV---- 294 Query: 291 TESGRQGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANP 350 +++ ++ +R +Y+G +S+ ++ E Q +++G D V++G FIANP Sbjct: 295 --------NQQIGDVVAWVRGSYSGVKISNLRYDFEEADQQIREGKVDAVAFGAKFIANP 346 Query: 351 DLVSRFKIDGELNKYNRKTFYTQDPVVGYTDYP 383 DLV R + D LN+ +T+YT+ VGY DYP Sbjct: 347 DLVERAQHDWPLNEPRPETYYTRT-AVGYNDYP 378 >4RNU-A nrPDB Length = 400 Score = 333 bits (854), Expect = 8e-92, Method: Composition-based stats. Identities = 112/299 (37%), Positives = 167/299 (55%), Gaps = 15/299 (5%) Query: 4 AQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALA-EYYAQRTT-PGGF 59 A G++N LF K+G +L HR V+ P+TR RAL+ +PN A EYY QR PG Sbjct: 109 ALGDTN--LFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTM 166 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQ 119 +I+EG +SP + G+ + PG++S+EQ+ W ++ A+H K F++ QLW +G A+ Sbjct: 167 IITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLWVLGWAAFPDNL 226 Query: 120 PNGGSPISSTNKPISENRWRVLLPDGSHVKYPKP-RALEASEIPRVVEDYCLSALNAIRA 178 G S S+N + + K P +L EI + +++Y +A N+I A Sbjct: 227 ARDGLRYDSA----SDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEYVQAAKNSIAA 282 Query: 179 GFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVR 238 G DG+EIH A+GYL++QFL N RTD+YGGSI NR RF +VV+ +V AIG KVG+R Sbjct: 283 GADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIENRARFTLEVVDALVEAIGHEKVGLR 342 Query: 239 VSPAIDHL---DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESG 294 +SP ++ ++ V G L K + G +LA++H+ +PR TE Sbjct: 343 LSPYGVFNSMSGGAETGIVAQYAYVAGELEK-RAKAGKRLAFVHLVEPRVTNPFLTEGE 400 Score = 99.4 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 35/96 (36%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Query: 299 DEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD---LVSYGRLFIANPDLVSR 355 E E + + G + +G F L + V++ D L+ YGR FI+NPDLV R Sbjct: 2 GEYEGGSNDFVYSIWKGPVIRAGNF--ALHPEVVREEVKDKRTLIGYGRFFISNPDLVDR 59 Query: 356 FKIDGELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL 391 + LNKY+R TFY Q GY DYP +L Sbjct: 60 LEKGLPLNKYDRDTFY-QMSAHGYIDYPTYEEALKL 94 >3KRZ-A nrPDB Length = 337 Score = 318 bits (814), Expect = 3e-87, Method: Composition-based stats. Identities = 102/345 (29%), Positives = 164/345 (47%), Gaps = 40/345 (11%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPG-GFLISEGTMVSP 69 L K+ + +R++++PM A +G+PN +YA R G G ++ E T V Sbjct: 4 LHMPLKIKDITIKNRIMMSPMCMYSASTDGMPNDWHIVHYATRAIGGVGLIMQEATAVES 63 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPN-GGSPISS 128 H GI++DEQV+ K++V+ A G + QL H GR + Y+ G SPI + Sbjct: 64 RGRITDHDLGIWNDEQVKELKKIVDICKANGAVMGIQLAHAGRKCNISYEDVVGPSPIKA 123 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 ++ Y PR L EI +V+ + +A A AG+D +EIH A Sbjct: 124 GDR------------------YKLPRELSVEEIKSIVKAFGEAAKRANLAGYDVVEIHAA 165 Query: 189 HGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASK-VGVRVSPAIDHLD 247 HGYLI +FL N R D+YG SI NR RFL +V++ V +K + VRVS A D+++ Sbjct: 166 HGYLIHEFLSPLSNKRKDEYGNSIENRARFLIEVIDEVRKNWPENKPIFVRVS-ADDYME 224 Query: 248 ATDSDPLSLGLAVVGML-NKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 + + + + + M+ +K+ ++ S L+V Y Y + K Sbjct: 225 GGIN--IDMMVEYINMIKDKVDLIDVSSGGLLNVDINLYPGY-------------QVKYA 269 Query: 307 KSLRMAYNGTFMSSGGF-NKELGMQAVQQGDADLVSYGRLFIANP 350 ++++ N + G +EL + + ADLV+ GR + NP Sbjct: 270 ETIKKRCNIKTSAVGLITTQELAEEILSNERADLVALGRELLRNP 314 >3GR7-A nrPDB Length = 340 Score = 305 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 95/350 (27%), Positives = 145/350 (41%), Gaps = 37/350 (10%) Query: 9 NETLFSSYKMGRFDLSHRVVLAPMTR--CRALNGVPNAALAEYYAQRTTP-GGFLISEGT 65 N LFS Y + L +R+V++PM C +G +Y R G +I E T Sbjct: 2 NTMLFSPYTIRGLTLKNRIVMSPMCMYSCDTKDGAVRTWHKIHYPARAVGQVGLIIVEAT 61 Query: 66 MVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSP 125 V+P GI+SD+ + +++V V G I QL H GR S G Sbjct: 62 GVTPQGRISERDLGIWSDDHIAGLRELVGLVKEHGAAIGIQLAHAGRKSQVP-----GEI 116 Query: 126 ISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 I+ + P ++ P P+ + ++I V+ + A A AGFD IEI Sbjct: 117 IAPSAVPFDDSS-------------PTPKEMTKADIEETVQAFQNGARRAKEAGFDVIEI 163 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDH 245 H AHGYLI++FL N R D+YGGS NR RFL +V++ V + + VR+S + H Sbjct: 164 HAAHGYLINEFLSPLSNRRQDEYGGSPENRYRFLGEVIDAVRE-VWDGPLFVRISASDYH 222 Query: 246 LDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKL 305 D + + QGV+ ++ + R + Y + Sbjct: 223 PDGLTAKDYVPYAKRMKE----QGVDLVDVSSGAIVPARMNVY----------PGYQVPF 268 Query: 306 MKSLRMAYNGTFMSSGGFNKE-LGMQAVQQGDADLVSYGRLFIANPDLVS 354 + +R + + G + +Q G ADLV GR + NP Sbjct: 269 AELIRREADIPTGAVGLITSGWQAEEILQNGRADLVFLGRELLRNPYWPY 318 >1Z48-A nrPDB Length = 338 Score = 304 bits (779), Expect = 3e-83, Method: Composition-based stats. Identities = 93/345 (26%), Positives = 148/345 (42%), Gaps = 35/345 (10%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRA--LNGVPNAALAEYYAQRT-TPGGFLISEGTMV 67 LF+ + L +R+V++PM + +G +Y R G +I E + V Sbjct: 4 KLFTPITIKDMTLKNRIVMSPMCMYSSHEKDGKLTPFHMAHYISRAIGQVGLIIVEASAV 63 Query: 68 SPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPIS 127 +P GI+SDE +E + ++ E V +G I QL H GR + G + Sbjct: 64 NPQGRITDQDLGIWSDEHIEGFAKLTEQVKEQGSKIGIQLAHAGRKAELE-----GDIFA 118 Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHG 187 + E P + A ++ V+++ +A A AGFD IEIH Sbjct: 119 PSAIAFDEQS-------------ATPVEMSAEKVKETVQEFKQAAARAKEAGFDVIEIHA 165 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLD 247 AHGYLI +FL N RTD+YGGS NR RFL+++++ V + + VRVS A D+ D Sbjct: 166 AHGYLIHEFLSPLSNHRTDEYGGSPENRYRFLREIIDEV-KQVWDGPLFVRVS-ASDYTD 223 Query: 248 ATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMK 307 +G A + ++ S A +H + Y + + K+ + Sbjct: 224 KGLDIADHIGFAKWMKEQGVDLIDCSSGALVHADINVFPGYQVSFA---------EKIRE 274 Query: 308 SLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDL 352 MA M + G + + +Q G ADL+ GR + +P Sbjct: 275 QADMATGAVGMITDG---SMAEEILQNGRADLIFIGRELLRDPFF 316 >5CPN-A nrPDB Length = 371 Score = 304 bits (778), Expect = 5e-83, Method: Composition-based stats. Identities = 99/348 (28%), Positives = 150/348 (43%), Gaps = 24/348 (6%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPG-GFLISEGTMVS 68 LF Y + L +R+ + PM + A +G+ N +YA G G L+ E T V+ Sbjct: 2 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGLINDWHQVHYASMARGGAGLLVVEATAVA 61 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 P P GI+SD +A+ VV+A+ A G Q+ H GR + A G I + Sbjct: 62 PEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIGA 121 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 + E + G+H+ PRA+ +I RV +D+ +A A AGF+ IE+H A Sbjct: 122 DDARGWETIAPSAIAFGAHLP-NVPRAMTLDDIARVKQDFVDAARRARDAGFEWIELHFA 180 Query: 189 HGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDA 248 HGYL F + N RTD YGGS NR RFL + + V + + + + D Sbjct: 181 HGYLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVRE-VWPENLPLTARFGVLEYDG 239 Query: 249 TDSDPLSLGLAV-----VGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEA 303 D L + + G L+ L G + ++ +G G Sbjct: 240 RDEQTLEESIELARRFKAGGLDLLSVSVGFTIPETNIP------WGPAFMG--------- 284 Query: 304 KLMKSLRMAYNGTFMSSGGF-NKELGMQAVQQGDADLVSYGRLFIANP 350 + + +R S+ GF +L A+Q DLVS GR +A+P Sbjct: 285 PIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADP 332 >5OCS-A nrPDB Length = 371 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 97/364 (26%), Positives = 155/364 (42%), Gaps = 25/364 (6%) Query: 10 ETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRT-TPGGFLISEGTMVS 68 LF Y++G +L++R+ +APM + A G + Q + G LI E T VS Sbjct: 2 PHLFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAVS 61 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGF-IFCQLWHVGRASHAVYQPNGGSPIS 127 P P G+Y+D A +V+ AV + QL H GR + + +GG I Sbjct: 62 PEGRITPTDLGLYNDANEAALGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQI- 120 Query: 128 STNKPISENRWRVLLPDGSHVKYPK--PRALEASEIPRVVEDYCLSALNAIRAGFDGIEI 185 +P W+ P + P AL+ + + ++ +D+ +A A R G +GIE+ Sbjct: 121 ---RPDQPRGWQTFAPSAVPHAAGEVPPAALDKAGMKKIRDDFVAAAKRAARLGIEGIEV 177 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASK-VGVRVSPAID 244 HGAHGYL+ QFL N RTD+YGGS+ NR RF +V + V A A + V +RVS Sbjct: 178 HGAHGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVSATDW 237 Query: 245 HLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAK 304 + D + +A+ L A +HV+ + G + Sbjct: 238 VPNGWD---IEGTIALSHEL------KARGSAAVHVSTGGVSPQQAIKIGP----GYQVP 284 Query: 305 LMKSLRMAYNGTFMSSGGFN-KELGMQAVQQGDADLVSYGRLFIANPDLVSR--FKIDGE 361 + ++ M+ G E + +AD++S R + +P K+ Sbjct: 285 YAQRVKAEVGLPTMAVGLITEAEQAEAIIANNEADIISIARAMLYDPRWPWHAAAKLGAS 344 Query: 362 LNKY 365 +N Sbjct: 345 VNAP 348 >1PS9-A nrPDB Length = 671 Score = 273 bits (698), Expect = 9e-74, Method: Composition-based stats. Identities = 95/363 (26%), Positives = 168/363 (46%), Gaps = 48/363 (13%) Query: 8 SNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAA--LAEYYAQRTTPGGFLISEGT 65 S +LF+ +G L +RV++ M L P+ A LA +YA+R G LI G Sbjct: 1 SYPSLFAPLDLGFTTLKNRVLMGSMHT--GLEEYPDGAERLAAFYAERARHGVALIVSG- 57 Query: 66 MVSPGSAGFPHVPGIYSDE--QVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGG 123 ++P G G ++ Q+ + + EAVH +GG I Q+ H GR S YQP+ Sbjct: 58 GIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQILHTGRYS---YQPHLV 114 Query: 124 SPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGI 183 +P S+ PI+ P L EI ++++++ A A AG+DG+ Sbjct: 115 AP-SALQAPINR---------------FVPHELSHEEILQLIDNFARCAQLAREAGYDGV 158 Query: 184 EIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAI 243 E+ G+ GYLI++FL N R+DQ+GG NR RF +VV V +G + + + Sbjct: 159 EVMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSML 218 Query: 244 DHL--DATDSDPLSLGLAV----VGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQG 297 D + T ++ + L A+ ++N G + +++ + PR Sbjct: 219 DLVEDGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPR------------- 265 Query: 298 SDEEEAKLMKSLRMAYNGTFMSSGGF-NKELGMQAVQQGDADLVSYGRLFIANPDLVSRF 356 + + + L+ + +++ + ++ + +GDAD+VS R F+A+ +L+S+ Sbjct: 266 --GAFSWVTRKLKGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKA 323 Query: 357 KID 359 + Sbjct: 324 QSG 326 >4RNX-A nrPDB Length = 400 Score = 267 bits (682), Expect = 6e-72, Method: Composition-based stats. Identities = 91/244 (37%), Positives = 131/244 (53%), Gaps = 14/244 (5%) Query: 154 RALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIA 213 +L EI + +++Y +A N+I AG DG+EIH A+GYL++QFL N RTD+YGGSI Sbjct: 8 HSLTKDEIKQYIKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIE 67 Query: 214 NRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHL---DATDSDPLSLGLAVVGMLNKLQGV 270 NR RF +VV+ +V AIG KVG+R+SP ++ ++ V G L K + Sbjct: 68 NRARFTLEVVDALVEAIGHEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVAGELEK-RAK 126 Query: 271 NGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQ 330 G +LA++H+ +PR TE + + + G + +G F L + Sbjct: 127 AGKRLAFVHLVEPRVTNPFLTEGEGEYEGGSN----DFVYSIWKGPVIRAGNF--ALHPE 180 Query: 331 AVQQGDAD---LVSYGRLFIANPDLVSRFKIDGELNKYNRKTFYTQDPVVGYTDYPFLAP 387 V++ D L+ YGR FI+NPDLV R + LNKY+R TFY Q GY DYP Sbjct: 181 VVREEVKDKRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFY-QMSAHGYIDYPTYEE 239 Query: 388 FSRL 391 +L Sbjct: 240 ALKL 243 Score = 162 bits (411), Expect = 2e-40, Method: Composition-based stats. Identities = 50/145 (34%), Positives = 80/145 (55%), Gaps = 7/145 (4%) Query: 4 AQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALN--GVPNAALA-EYYAQRTT-PGGF 59 A G++N LF K+G +L HR V+ P+TR RAL+ +PN A EYY QR PG Sbjct: 258 ALGDTN--LFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTM 315 Query: 60 LISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQ 119 +I+EG +SP + G+ + PG++S+EQ+ W ++ A+H K F++ QLW +G A+ Sbjct: 316 IITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLWVLGWAAFPDNL 375 Query: 120 P-NGGSPISSTNKPISENRWRVLLP 143 +G S+++ + Sbjct: 376 ARDGLRYDSASDNVFMDAEQEAKAK 400 >3L5A-A nrPDB Length = 419 Score = 261 bits (668), Expect = 3e-70, Method: Composition-based stats. Identities = 87/362 (24%), Positives = 133/362 (36%), Gaps = 34/362 (9%) Query: 11 TLFSSYKM-GRFDLSHRVVLAPMT-RCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVS 68 L S + +S+R VL+PMT G A Y A+R+ G ++ + Sbjct: 26 PLLQSIHLPNGIKISNRFVLSPMTVNASTKEGYITKADLAYAARRSNSAGMQVTGAAYIE 85 Query: 69 PGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 P F + I D + + + G QL H GR S+ N G Sbjct: 86 PYGKLFEYGFNIDHDACIPGLTNMASTMKQHGSLAIIQLAHAGRFSNQAIL-NFGKVYGP 144 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 + + V++ A+ +I +++ Y + L AI+AGFDG+EI A Sbjct: 145 SPMTLHSPIEHVVI------------AMSHEKINSIIQQYRDATLRAIKAGFDGVEISIA 192 Query: 189 HGYLIDQFLKDGINDRTDQYGG-SIANRCRFLKQVVEGVVSAIGASK-----VGVRVSPA 242 LI F N RTD YG S+ NR R +V+ V I +G R +P Sbjct: 193 QRLLIQTFFSTFSNRRTDHYGADSLKNRARLCLEVMRAVQEVIDKEAPDNFILGFRATPE 252 Query: 243 IDHLDATDSDPLSLGLAVVGMLNKLQGV--NGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 + SD + N+L + S + YL + H Y T Sbjct: 253 ----ETRGSD----LGYTIDEFNQLIDWVMDVSNIQYLAIASWGRHIYQNTSRTPGDHFG 304 Query: 301 EEAKLMKSLRMAYNGTFMSSGGFNK-ELGMQAVQQGDADLVSYGRLFIANPDLVSRFKID 359 + +A ++SGG N E + A+Q AD+V F+ PD V + Sbjct: 305 RPVNQIVYEHLAGRIPLIASGGINSPESALDALQH--ADMVGMSSPFVTEPDFVHKLAEQ 362 Query: 360 GE 361 Sbjct: 363 RP 364 >3HF3-A nrPDB Length = 349 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 96/364 (26%), Positives = 143/364 (39%), Gaps = 27/364 (7%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRA-LNGVPNAALAEYYAQRTTPG-GFLISEGTMVSP 69 LF+ ++G L +R+ ++PM + A L G +Y R G G ++ E T V P Sbjct: 4 LFTPLELGGLRLKNRLAMSPMCQYSATLEGEVTDWHLLHYPTRALGGVGLILVEATAVEP 63 Query: 70 GSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 P+ GI+S++ + K++ + G QL H GR + GG P+ Sbjct: 64 LGRISPYDLGIWSEDHLPGLKELARRIREAGAVPGIQLAHAGRKAGTARPWEGGKPLG-- 121 Query: 130 NKPISENRWRVLLPDGSHVK--YPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHG 187 WRV+ P YP P L+ + + R+++ + A A+RAGF IE+H Sbjct: 122 --------WRVVGPSPIPFDEGYPVPEPLDEAGMERILQAFVEGARRALRAGFQVIELHM 173 Query: 188 AHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGAS-KVGVRVSPAIDHL 246 AHGYL+ FL N RTD YGGS+ NR RF QV + V + + VRVS Sbjct: 174 AHGYLLSSFLSPLSNQRTDAYGGSLENRMRFPLQVAQAVREVVPRELPLFVRVSATDWGE 233 Query: 247 DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 + + L S L V P + Q + + Sbjct: 234 GGWSLEDTLAFARRLKELGVDLLDCSSGGVVLRVRIPLAPGF-------QVPFADAVRKR 286 Query: 307 KSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYN 366 LR G E +Q G ADLV GR+ + +P R + Sbjct: 287 VGLRTGAVGLIT-----TPEQAETLLQAGSADLVLLGRVLLRDPYFPLRAAKALGVAPEV 341 Query: 367 RKTF 370 + Sbjct: 342 PPQY 345 >3K30-A nrPDB Length = 690 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 78/354 (22%), Positives = 144/354 (40%), Gaps = 33/354 (9%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGG--FLISEGTMVSP 69 LF ++G F +R P G + + + GG + +E + Sbjct: 14 LFEPVQIGPFTTKNRFYQVPHCNGM---GYRDPSAQASMRKIKAEGGWSAVCTEQVEIHA 70 Query: 70 GSAGFPH-VPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISS 128 S P I+ D+ + A K++ +A+H GG +L H G +A Q + +P+ Sbjct: 71 TSDIAPFIELRIWDDQDLPALKRIADAIHEGGGLAGIELAHNG--MNAPNQLSRETPLGP 128 Query: 129 TNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGA 188 + P++ + + + RA+ +I + + + +I AG+D + ++GA Sbjct: 129 GHLPVAPDT----------IAPIQARAMTKQDIDDLRRWHRNAVRRSIEAGYDIVYVYGA 178 Query: 189 HGYL-IDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVV-SAIGASKVGVRVSPAIDHL 246 HGY + FL N RTD+YGGS+ NR R L++++E + G + V R++ + Sbjct: 179 HGYSGVHHFLSKRYNQRTDEYGGSLENRMRLLRELLEDTLDECAGRAAVACRITVEEEID 238 Query: 247 DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLM 306 + + L +G L L VT R+ G+ E + + Sbjct: 239 GGITREDIEGVLRELGELPDLWDFAMGSWEGDSVTS-RFAPEGRQE-----------EFV 286 Query: 307 KSLRMAYNGTFMSSGGFNKELGM-QAVQQGDADLVSYGRLFIANPDLVSRFKID 359 L+ + G F M + ++ G DL+ R IA+P L ++ + Sbjct: 287 AGLKKLTTKPVVGVGRFTSPDAMVRQIKAGILDLIGAARPSIADPFLPNKIRDG 340 >2TMD-A nrPDB Length = 729 Score = 217 bits (552), Expect = 7e-57, Method: Composition-based stats. Identities = 74/355 (20%), Positives = 138/355 (38%), Gaps = 33/355 (9%) Query: 12 LFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPG-GFLISEGTMVSPG 70 LF ++G L +R P + + + + + G L +E ++P Sbjct: 9 LFEPIQIGPKTLRNRFYQVPHCIGAGSD--KPGFQSAHRSVKAEGGWAALNTEYCSINPE 66 Query: 71 SAGFPH-VPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISST 129 S I+ + V K + + VH G +LW+ G +HA + S Sbjct: 67 SDDTHRLSARIWDEGDVRNLKAMTDEVHKYGALAGVELWYGG--AHAPN-------MESR 117 Query: 130 NKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAH 189 P +++ S+ + ++ S+I +V + Y +A + AGFD + ++GAH Sbjct: 118 ATPRGPSQYASEFETLSYC-----KEMDLSDIAQVQQFYVDAAKRSRDAGFDIVYVYGAH 172 Query: 190 GYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGAS-KVGVRVSPAIDHLDA 248 YL QFL N RTD+YGGS+ NR RF + +E V A+G+ + R + Sbjct: 173 SYLPLQFLNPYYNKRTDKYGGSLENRARFWLETLEKVKHAVGSDCAIATRFGVDTVYGPG 232 Query: 249 TDSDPLSL--GLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQ-GSDEEEAKL 305 + + + L + + +A +G+ + Sbjct: 233 QIEAEVDGQKFVEMADSLVDMWDITIGDIAE----------WGEDAGPSRFYQQGHTIPW 282 Query: 306 MKSLRMAYNGTFMSSGGFN-KELGMQAVQQGDADLVSYGRLFIANPDLVSRFKID 359 +K ++ + G + E ++ V +G AD++ R IA+P L + + Sbjct: 283 VKLVKQVSKKPVLGVGRYTDPEKMIEIVTKGYADIIGCARPSIADPFLPQKVEQG 337 >1VC4-A nrPDB Length = 254 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 25/49 (51%), Gaps = 1/49 (2%) Query: 310 RMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKI 358 + + G ++ G++++ ++A+ +G D V G + PDL + + Sbjct: 204 KRGFGGVLVAESGYSRKEELKAL-EGLFDAVLIGTSLMRAPDLEAALRE 251 >4BF9-A nrPDB Length = 338 Score = 32.4 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 56/171 (32%), Gaps = 33/171 (19%) Query: 209 GGSIANRCRFLKQVVEGVVSAIGAS-KVGVRVSPAIDHLDATDSDPLSLGLAVVGMLNKL 267 G ++ + Q + + A+ A V V+V D + ++ A L Sbjct: 132 GATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATEL--- 188 Query: 268 QGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSLRMAYNGTFMSSGG-FNKE 326 +G+T+ ++ + + + +R N +++G ++ + Sbjct: 189 ------------------VVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQ 230 Query: 327 LGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGE----------LNKYNR 367 Q + D V GR + P+L K + L KY R Sbjct: 231 SAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTR 281 >6BYC-A nrPDB Length = 862 Score = 32.0 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 44/131 (33%), Gaps = 28/131 (21%) Query: 11 TLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPG 70 L+S K + L+ + P A P A + Y ++ P Sbjct: 137 KLYSPIKKIQPWLAKQPYALPGAYDSAFGDEPEARHSSTYVRKA--------------PY 182 Query: 71 SAGFPHVP-----GIYSDEQVEAWKQV-VEAVH-------AKGGFIFCQL-WHVGRASHA 116 + G+ P GI+ D +VEAW V V+ +H A + QL GR+ Sbjct: 183 NFGWDWGPRMVNAGIWKDVRVEAWDAVRVDGLHIAQQRVDAHSAQVQAQLDLQAGRSGPV 242 Query: 117 VYQPNGGSPIS 127 + P Sbjct: 243 QVTLDVLGPDG 253 >2IBG-E nrPDB Length = 150 Score = 31.6 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 21/56 (37%) Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGI 183 + + W G + + RA+ + R Y + A A+ AGFD + Sbjct: 80 PGIRLLVTESWDEDYHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWV 135 >3BHF-A nrPDB Length = 390 Score = 31.3 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 54/155 (34%), Gaps = 22/155 (14%) Query: 240 SPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSD 299 + + ++A L++ L +NK + + V + Y+A + SG S+ Sbjct: 100 AFVAETMEAAKEHSLTVDLLEGDEINK-------RWPGITVPEN-YNAIFEPNSGVLFSE 151 Query: 300 EEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDAD--------LVSYGRLFIANPD 351 + + + ++ +V+ A+ +VS G N Sbjct: 152 NCIRAYRELAEARGAKVLTHTRVEDFDISPDSVKIETANGSYTADKLIVSMGAW---NSK 208 Query: 352 LVSRFKIDGELNKYNRKTFYTQDPVVGY---TDYP 383 L+S+ +D L Y + + + Y D+P Sbjct: 209 LLSKLNLDIPLQPYRQVVGFFESDESKYSNDIDFP 243 >1OK6-A nrPDB Length = 263 Score = 30.9 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 37/189 (19%), Positives = 65/189 (34%), Gaps = 21/189 (11%) Query: 173 LNAIRAGFDGI--EIHGAHGYLIDQF-LKDGINDRTDQYGGSIANRCRFLKQVVEGVVSA 229 A AGFDG+ + A Y L +N +T Y G + + E V + Sbjct: 48 RLARDAGFDGVVFQRGIAEKYYDGSVPLILKLNGKTTLYNGEPVSVANCSVE--EAV--S 103 Query: 230 IGASKVGVRVSPAIDHL-DATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAY 288 +GAS VG + P + AV L + ++ T P AY Sbjct: 104 LGASAVGYTIYPGSGFEWKMFEELARIKRDAVKFDLPLVVWSYPRGGKVVNETAPEIVAY 163 Query: 289 GQTESGRQGSD-------EEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQ--QGDADL 339 + G+D + ++++A + SGG + ++ +G + Sbjct: 164 AARIALELGADAMKIKYTGDPKTFSWAVKVAGKVPVLMSGGPKTKTEEDFLKQVEGVLEA 223 Query: 340 ----VSYGR 344 ++ GR Sbjct: 224 GALGIAVGR 232 >2WG3-A nrPDB Length = 164 Score = 30.9 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 20/57 (35%) Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 + W + + RAL+ + R Y L A A+ AGFD + Sbjct: 81 PGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVY 137 >3N1G-B nrPDB Length = 170 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 20/57 (35%) Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 + W + + RAL+ + R Y L A A+ AGFD + Sbjct: 100 PGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVY 156 >5OTA-A nrPDB Length = 265 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 23/46 (50%), Gaps = 2/46 (4%) Query: 307 KSLRMAYNG--TFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANP 350 K + A++G +++G ++ + +Q ++++ R ++ P Sbjct: 47 KFVEQAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYLLTP 92 >1Y0E-A nrPDB Length = 223 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 41/108 (37%), Gaps = 21/108 (19%) Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFD--GIEI 185 + + + + L S+++ P ++I V E A NA R GFD G + Sbjct: 93 ALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATVEE-----AKNAARLGFDYIGTTL 147 Query: 186 HGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGAS 233 HG Y Q L N +FLK V++ V + + A Sbjct: 148 HGYTSYTQGQLL--------------YQNDFQFLKDVLQSVDAKVIAE 181 >3O15-A nrPDB Length = 235 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 20/141 (14%), Positives = 43/141 (30%), Gaps = 13/141 (9%) Query: 213 ANRCRFLKQVVEGVVSAIG-------ASKVGVRVSPAIDHLDATDSDPLSLGLAVVGMLN 265 R +F + + G ++ + + H+ D++ + A+ M+ Sbjct: 69 EARIKFA-EKAQAACREAGVPFIVNDDVELALNLKADGIHIGQEDANAKEVRAAIGDMIL 127 Query: 266 KLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSL----RMAYNGTFMSSG 321 + S++ Y G D + + + R + + G Sbjct: 128 GVSAHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGVSLIEAVRRQGISIPIVGIG 187 Query: 322 GFNKELGMQAVQQGDADLVSY 342 G + +Q G AD VS Sbjct: 188 GITIDNAAPVIQAG-ADGVSM 207 >4U3W-A nrPDB Length = 505 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 14/105 (13%), Positives = 31/105 (29%), Gaps = 5/105 (4%) Query: 90 KQVVEAVHAKGGFI--FCQLWHVGRASH--AVYQPNGGSPISSTNKPISENRWRVLLPDG 145 +++ + A + Q H + + + + I + + Sbjct: 48 RKLADVCEADAALVDSAVQAAHAAQKAGWRDTTPAQRAAWLHKIADGIEARFDEFVAAEV 107 Query: 146 SHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHG 190 + P +A I R + ++ A A + E H A G Sbjct: 108 ADTGRPVAQARTLD-IARGIANFRTFADLVRTASGEYFETHAADG 151 >4B3J-A nrPDB Length = 736 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 33/92 (35%), Gaps = 6/92 (6%) Query: 83 DEQVEAWKQ-VVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTNKPISENRWRVL 141 +E V A K + E + A Q W Y+ GG+P S I + L Sbjct: 211 EELVPAAKAWIKEELKANPDGAGVQPW-----DKKGYKMPGGTPSSPGLAAILPSFPSNL 265 Query: 142 LPDGSHVKYPKPRALEASEIPRVVEDYCLSAL 173 P PRA+ A+ + D+ ++ Sbjct: 266 RKQLKGAPMPAPRAILAAAVEGAQVDFDTASR 297 >3L1R-A nrPDB Length = 478 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 45/258 (17%), Positives = 81/258 (31%), Gaps = 36/258 (13%) Query: 74 FPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVY--------QPNGGS- 124 + G+Y ++ V+ ++ ++V G + L GR ++ QPNG + Sbjct: 97 YKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPAT 156 Query: 125 PISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 P+ + P + ++ P A S+ + Y ++ A + Sbjct: 157 PVDMVVDYYKFDYEFAEPPRVTSLQNTVPLA-TFSDFGD--DVYFVADQRGYEA---VVY 210 Query: 185 IHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAID 244 YL Q+LK D+ G + R + VV I S GV V + Sbjct: 211 ------YLAGQYLKTD-----DKSGKIVDPRLQL-----NKVVREIKYSPGGVTVKTEDN 254 Query: 245 HLDATDSDPLS-----LGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSD 299 + + D +S L ++ KL + + Sbjct: 255 SVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTMIFLKFPRKFWPEGK 314 Query: 300 EEEAKLMKSLRMAYNGTF 317 E L S R Y G + Sbjct: 315 GREFFLYASSRRGYYGVW 332 >3K7I-B nrPDB Length = 187 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 20/57 (35%) Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 K W + + RA++ + R Y L A A+ AGFD + Sbjct: 108 PGVKLRVTKGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVY 164 >2BAA-A nrPDB Length = 243 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 30/117 (25%), Gaps = 17/117 (14%) Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 P + D+ V L + A + + E G Sbjct: 42 PGFGTTGSADAQKRE----VAAFLAQTSHETTGGWATAPDGAFAWGYCFKQERGASSDYC 97 Query: 301 EEAKLMK---SLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVS 354 + R G S +N +A+ G +ANPDLV+ Sbjct: 98 TPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAI----------GVDLLANPDLVA 144 >3IWR-A nrPDB Length = 309 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 26/110 (23%), Gaps = 13/110 (11%) Query: 248 ATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMK 307 + + V L + + + E + + Sbjct: 101 GGTGNTETRKREVAAFLGQTSHETTGGWPTAPDGPFSWGYCFKQEQNPPSDYCQPSPEWP 160 Query: 308 SLRMA---YNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVS 354 G S FN +A+ G ++NPDLV+ Sbjct: 161 CAPGRKYYGRGPIQLSFNFNYGPAGRAI----------GVDLLSNPDLVA 200 >6DVI-A nrPDB Length = 394 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 27/96 (28%), Gaps = 15/96 (15%) Query: 105 CQLWHVGRASHAVYQPNGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEI--- 161 +LW A+ + P G + + + + G +I Sbjct: 83 VELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKH 142 Query: 162 ----PRVVEDY----CLSA----LNAIRAGFDGIEI 185 P + Y A A AG+DG+ I Sbjct: 143 AGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVI 178 >6DMY-B nrPDB Length = 177 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 20/57 (35%) Query: 128 STNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIE 184 K W + + RA++ + R Y + A A+ AGFD + Sbjct: 98 PGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVY 154 >4DYG-A nrPDB Length = 244 Score = 28.2 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 30/117 (25%), Gaps = 17/117 (14%) Query: 241 PAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDE 300 P +TD+ V L + A + + E G Sbjct: 43 PGFGATGSTDARKRD----VAAFLAQTSHETTGGWATAPDGAFAWGYCFKQERGAAADYC 98 Query: 301 EEAKLMK---SLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVS 354 + R G S +N +A+ G + NPDLV+ Sbjct: 99 TPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAI----------GVDLLRNPDLVA 145 >3F4N-A nrPDB Length = 246 Score = 28.2 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 39/116 (33%), Gaps = 22/116 (18%) Query: 164 VVEDYCLSALNAIRAGFDGIEIHGAHGYLIDQFLKDGINDRTDQ----YGGSIANRCRFL 219 + D +A A +AG DGI +H L++ TD+ +I R Sbjct: 26 IYPDPVQAAFIAEQAGADGITVH----------LREDRRHITDRDVRILRQTIQTRMNLE 75 Query: 220 KQVVEGVVSAIGASKVGVRVSPAI--DHLDATDSDPLSLGLAVVGMLNKLQGVNGS 273 V + +V + + P + GL V G ++K+ G Sbjct: 76 MAVTDEMVD------IACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLAVGR 125 >2Z1Q-A nrPDB Length = 577 Score = 28.2 bits (61), Expect = 6.8, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 17/41 (41%) Query: 139 RVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAG 179 R++ D + V Y R L E +V +A + AG Sbjct: 531 RLVEGDEARVVYSAARRLTKREPGDLVALRRQAAEAVLEAG 571 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.127 0.351 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,048,144 Number of Sequences: 36641 Number of extensions: 630854 Number of successful extensions: 2137 Number of sequences better than 10.0: 60 Number of HSP's better than 10.0 without gapping: 82 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 1809 Number of HSP's gapped (non-prelim): 127 length of query: 391 length of database: 10,336,785 effective HSP length: 99 effective length of query: 292 effective length of database: 6,709,326 effective search space: 1959123192 effective search space used: 1959123192 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)