BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9FRL8 (213 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5LOL-A nrPDB 428 e-121 5N9U-A nrPDB 343 4e-95 5ELG-A nrPDB 338 7e-94 5IQY-A nrPDB 304 2e-83 5D9W-A nrPDB 301 2e-82 2D2Z-A nrPDB 87 8e-18 2R5G-A nrPDB 84 4e-17 5Y7I-A nrPDB 84 6e-17 4K0G-A nrPDB 80 7e-16 3FY7-A nrPDB 72 1e-13 4QQ7-A nrPDB 61 3e-10 3LFL-A nrPDB 58 4e-09 5J5N-A nrPDB 56 1e-08 4PQI-A nrPDB 55 2e-08 3QAG-A nrPDB 54 5e-08 3RBT-A nrPDB 53 1e-07 3WD6-A nrPDB 52 1e-07 1FW1-A nrPDB 52 1e-07 4AGS-A nrPDB 51 4e-07 2YV7-A nrPDB 50 5e-07 2CZ2-A nrPDB 47 7e-06 4J2F-A nrPDB 46 1e-05 1E6B-A nrPDB 44 4e-05 3UBL-A nrPDB 44 7e-05 5ECL-B nrPDB 43 1e-04 4CHS-A nrPDB 43 1e-04 2VO4-A nrPDB 42 1e-04 4IGJ-A nrPDB 39 0.002 6EP7-A nrPDB 39 0.002 4PNG-A nrPDB 39 0.002 4YH2-A nrPDB 38 0.003 1JLV-A nrPDB 37 0.006 3UAR-A nrPDB 36 0.009 2PMT-A nrPDB 36 0.010 1OYJ-A nrPDB 36 0.013 3VWX-A nrPDB 35 0.019 3NIV-A nrPDB 35 0.020 3PR8-A nrPDB 34 0.040 1PN9-A nrPDB 34 0.048 2JL4-A nrPDB 34 0.050 4RI7-A nrPDB 33 0.074 3M8N-A nrPDB 33 0.083 4MPF-A nrPDB 33 0.095 3TOT-A nrPDB 33 0.096 5EY6-A nrPDB 33 0.11 5ZWP-A nrPDB 33 0.13 4IKH-A nrPDB 32 0.14 2VCT-A nrPDB 32 0.15 3M3M-A nrPDB 32 0.16 2VCV-A nrPDB 32 0.21 3I6A-A nrPDB 32 0.28 6F05-A nrPDB 31 0.32 2YV9-A nrPDB 31 0.35 4MK3-A nrPDB 31 0.39 4M2B-A nrPDB 31 0.41 5NR1-A nrPDB 31 0.47 2GDR-A nrPDB 31 0.49 1PL2-A nrPDB 31 0.50 1F3B-A nrPDB 30 0.66 1F2E-A nrPDB 30 0.76 1KHW-A nrPDB 30 1.1 3MAK-A nrPDB 29 1.7 5F06-A nrPDB 29 1.7 1EXZ-A nrPDB 28 2.2 2CA8-A nrPDB 28 2.3 3R2Q-A nrPDB 28 2.4 1SCF-A nrPDB 28 2.5 1CEM-A nrPDB 28 2.7 3UAN-A nrPDB 28 3.1 6JWK-A nrPDB 28 3.7 3GH6-A nrPDB 28 4.1 5N8X-A nrPDB 28 4.3 4D10-E nrPDB 27 4.8 3QMX-A nrPDB 27 5.2 4F7O-A nrPDB 27 5.6 2IL3-A nrPDB 27 5.6 1U3I-A nrPDB 27 5.6 1YQ1-A nrPDB 27 6.2 2O26-A nrPDB 27 7.0 1ZRH-A nrPDB 27 8.7 5YHP-A nrPDB 27 8.7 1WP9-A nrPDB 27 9.0 >5LOL-A nrPDB Length = 215 Score = 428 bits (1101), Expect = e-121, Method: Compositional matrix adjust. Identities = 213/213 (100%), Positives = 213/213 (100%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV Sbjct: 3 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 62 Query: 61 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 120 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE Sbjct: 63 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 122 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV Sbjct: 123 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 182 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA Sbjct: 183 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA 215 >5N9U-A nrPDB Length = 218 Score = 343 bits (879), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 165/213 (77%), Positives = 191/213 (89%), Gaps = 1/213 (0%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MAL+ICVK AVGAP++LGDCPF QRVLL+LEEKK+PYK+HLIN+ DKPQWFL+ISPEGKV Sbjct: 1 MALEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKV 60 Query: 61 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 120 PVVK+D KWVADSDVIVG+LEEK PEP L TPPEFASVGSKIF +FV FLKSKD NDG+E Sbjct: 61 PVVKIDDKWVADSDVIVGILEEKNPEPPLATPPEFASVGSKIFPSFVKFLKSKDPNDGTE 120 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 +AL++EL+AL+ HLK H GPF+AGEKITAVDLSLAPKLYHLEVALGH+KNW +P++LT V Sbjct: 121 QALLEELKALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHV 179 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 NY K LFSRESF+ T+A +E V+AGWE KVNA Sbjct: 180 LNYIKLLFSRESFKKTRAAEEHVIAGWEPKVNA 212 >5ELG-A nrPDB Length = 221 Score = 338 bits (868), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 161/212 (75%), Positives = 184/212 (86%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MAL+ICVK AVGAPD LGDCPFSQR LLTLEEK L YK HLIN+SDKPQWFLDISP+GKV Sbjct: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 Query: 61 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 120 PV+K+D KWV DSDVIVG+LEEKYP+P LKTP EFASVGS IFG F TFLKSKD+NDGSE Sbjct: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 AL+ ELEALENHLK+H GPF+AGE+++AVDLSLAPKLYHL+VALGH+K+WSVPES V Sbjct: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 NY K LFS +SFE TK +++ V++GW KVN Sbjct: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 >5IQY-A nrPDB Length = 216 Score = 304 bits (779), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 145/214 (67%), Positives = 179/214 (83%), Gaps = 2/214 (0%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MA+++CVK AVGAPD+LGDCPFSQRVLLTLEEKK+ Y+ L+++S+KP+WFL ISPEGKV Sbjct: 4 MAVEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKV 63 Query: 61 PVVKL-DGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGS 119 PV DGKW+ADSDVI ++EEK+P PSL TPPE+ASVGSKIF +FV FLKSKDA+DGS Sbjct: 64 PVFNSGDGKWIADSDVITQVIEEKFPTPSLVTPPEYASVGSKIFPSFVKFLKSKDASDGS 123 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 EKAL+DEL+AL+ HLK H GP+++GE ++A DLSL PKL+HL+VAL H+K W +PE+LTS Sbjct: 124 EKALLDELQALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTS 182 Query: 180 VRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 V Y KALFSRESF TK + ++AGW KVNA Sbjct: 183 VHAYTKALFSRESFVKTKPANQYLIAGWAPKVNA 216 >5D9W-A nrPDB Length = 230 Score = 301 bits (770), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 148/214 (69%), Positives = 171/214 (79%), Gaps = 2/214 (0%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 M +++CVK AVG PD LGD PFSQRVLLTLEEKK+PY+ LI+V +KP WFL ISPEGKV Sbjct: 18 MGVEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKV 77 Query: 61 PVVKL-DGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGS 119 PV DGKW+ DSDVI ++EEKYP PSL TPPE+ASVGSKIF F TFLKSKD NDGS Sbjct: 78 PVFNGGDGKWIPDSDVITQVIEEKYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDPNDGS 137 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 EKAL+ EL+ALE HLK H GPF+ G+ I+A DLSLAPKLYHL+VAL H+K W +PE LT+ Sbjct: 138 EKALLTELQALEEHLKAH-GPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTN 196 Query: 180 VRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 V Y +ALFSRESF TKA KE ++AGW KVNA Sbjct: 197 VHAYTEALFSRESFIKTKAAKEHLIAGWAPKVNA 230 >2D2Z-A nrPDB Length = 261 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 59/213 (27%), Positives = 106/213 (49%), Gaps = 25/213 (11%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 +G+CPFSQR+ + L K + + +++ KP +++P P + + + D + I Sbjct: 32 IGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKI 91 Query: 77 VGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSK--DANDGSEKALVDELEA 129 LEE KY + S K P E + G IF F ++K+ +AN+ E+ L+ L+ Sbjct: 92 EEFLEEVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 Query: 130 LENHL----------------KTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV 173 L+ +L K + F+ G ++T D +L PKL+ ++V Y+N+ + Sbjct: 151 LDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 Query: 174 PESLTSVRNYAKALFSRESFENT-KAKKEIVVA 205 P+ +T + Y +SR+ F NT + KE+ +A Sbjct: 211 PKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIA 243 >2R5G-A nrPDB Length = 247 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 56/203 (27%), Positives = 99/203 (48%), Gaps = 24/203 (11%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 +G+CPF QR+ + L K + + ++++ KP+ D++P P + + + D I Sbjct: 27 IGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKI 86 Query: 77 VGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKS--KDANDGSEKALVDELEA 129 LE+ +YP S K F VG +F F ++K+ K+AN EK+L+ E + Sbjct: 87 EEFLEQTLAPPRYPHLSPKYKESF-DVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKR 145 Query: 130 LENHLKT----------------HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV 173 L+++L T F+ G+++T D SL PKL ++VA Y+++ + Sbjct: 146 LDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDI 205 Query: 174 PESLTSVRNYAKALFSRESFENT 196 P + V Y ++RE F +T Sbjct: 206 PAEFSGVWRYLHNAYAREEFTHT 228 >5Y7I-A nrPDB Length = 261 Score = 83.6 bits (205), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 93/201 (46%), Gaps = 22/201 (10%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 +G+CPF QR+ + L K + + +++ KP D++P P + +G D I Sbjct: 43 VGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAPGTNPPFLLYNGTLKTDFIKI 102 Query: 77 VGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSEKALVDELEALE 131 LE+ +YP S F VG+ IF F F+K+ N EK L+ E + L+ Sbjct: 103 EEFLEQTLAPPRYPHLSPVNKESF-DVGADIFAKFSAFIKNSPNNPLQEKNLLREFKRLD 161 Query: 132 NHLKT----------------HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPE 175 ++L + + F+ G+++T D +L PKL+ + VA Y N+ +P+ Sbjct: 162 DYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRVAAKKYCNFEIPD 221 Query: 176 SLTSVRNYAKALFSRESFENT 196 T V Y K R+ F+ T Sbjct: 222 HFTGVWRYLKNADERDEFKQT 242 >4K0G-A nrPDB Length = 251 Score = 80.1 bits (196), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 54/220 (24%), Positives = 101/220 (45%), Gaps = 24/220 (10%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 +G+ PFSQR+ + L K + + ++ + + + P G++P + + D++ I Sbjct: 31 IGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKI 90 Query: 77 VGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDA--NDGSEKALVDELEA 129 LE +YP+ + P E + G IF F ++K+ + ND EK L+ L+ Sbjct: 91 EEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKV 149 Query: 130 LENHLKT----------------HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV 173 L+N+L + F+ G ++T D +L PKL+ ++V Y+ +++ Sbjct: 150 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTI 209 Query: 174 PESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 PE+ V Y ++RE F +T E + +E A Sbjct: 210 PEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 249 >3FY7-A nrPDB Length = 250 Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 32/218 (14%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 +G CP QR+ + L K +P+ ++ P D +P ++P++ D D+ I Sbjct: 39 VGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPILLYDSDAKTDTLQI 98 Query: 77 VGLLEEKYPEPSLKTPPEFASV----------GSKIFGAFVTFLKSK--DANDGSEKALV 124 LEE PP+F S+ G+ +F F F+K+ ++ + L+ Sbjct: 99 EDFLEETL------GPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLL 152 Query: 125 DELEALENHLKT--------------HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKN 170 L L+++L+ F+ G+++T D SL PKL+ ++ H++ Sbjct: 153 RALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQ 212 Query: 171 WSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWE 208 +P L VR Y + + F+ T ++A + Sbjct: 213 APIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAYR 250 >4QQ7-A nrPDB Length = 207 Score = 61.2 bits (147), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 49/190 (25%), Positives = 94/190 (49%), Gaps = 25/190 (13%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGL 79 CPFSQR L L EK + ++ +++ +KP+ ++P G+VP++ + +S++I Sbjct: 14 CPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINEY 73 Query: 80 LEEKYPEPSLKTPPEFASVGSKIF--------GAFVTFL---KSKDANDGSEKALVDELE 128 ++E++P P L +++F V+ L K K A EKA + Sbjct: 74 IDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARL---- 129 Query: 129 ALENHLKTHSGPFVA-----GEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNY 183 A+ + L + FV GE+ + +D+++AP L+ L+ HY + ++ + Y Sbjct: 130 AIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLD----HY-GIELSKNAAPLMKY 184 Query: 184 AKALFSRESF 193 A+ +FSR ++ Sbjct: 185 AERIFSRPAY 194 >3LFL-A nrPDB Length = 240 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 45/154 (29%), Positives = 74/154 (48%), Gaps = 12/154 (7%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVK-LDGKWVADSDVIVG 78 CPF++R L L+ K + ++ IN+ +KP+WF +P G VPV++ G+ + +S + Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 79 LLEEKYPEPSL--KTPPEFAS------VGSKIFGAFVTFLKSKDAND--GSEKALVDELE 128 L+E YP L P E A + SK+ +F++S++ D G ++ E Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 Query: 129 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 LE L F G I+ +D + P LE Sbjct: 152 KLE-VLTNKKTTFFGGNSISMIDYLIWPWFERLE 184 >5J5N-A nrPDB Length = 231 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 48/185 (25%), Positives = 85/185 (45%), Gaps = 17/185 (9%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGK-VPVVKLDGKWVADSDVIVGL 79 PF RV L L EK + Y+ ++ +K L ++P K +PV+ +GK V +S +IV Sbjct: 26 PFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQY 85 Query: 80 LEEKYPE--PSLKTPPEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDEL 127 ++E + + P L + P + S+ + FV + K + + ++K +D L Sbjct: 86 IDEVWKDSAPLLPSDP-YQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDSL 144 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 + +E L P+ GE I VD++L P Y A N+++ + Y K Sbjct: 145 KLMEGELGDK--PYFGGETIGYVDIALVP-FYSWFYAYETIGNFNIEAECPKMIAYCKRC 201 Query: 188 FSRES 192 +E+ Sbjct: 202 LQKET 206 >4PQI-A nrPDB Length = 241 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 54/206 (26%), Positives = 94/206 (45%), Gaps = 17/206 (8%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINV--SDKPQWFLD-ISPEGKVPVVKLDGKWVADSDVI 76 CPF+QRV +T K L + L+ + ++P W+ + + P KVP ++ +GK +S + Sbjct: 41 CPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLDL 100 Query: 77 VGLLEEKYPEPSL--KTPP--EFA----SVGSKIFGAFVTFLKSKDANDGSEKALVDELE 128 + LE + PSL K P EFA S K G T K A + + Sbjct: 101 IKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAKEAGPA-----FD 155 Query: 129 ALENHL-KTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 LEN L K GPF G++ + VD++ P + L + L + + + + + + Sbjct: 156 HLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEEV 215 Query: 188 FSRESFENTKAKKEIVVAGWESKVNA 213 E+++ TK + +V ++ + A Sbjct: 216 NKIEAYKQTKTDPKELVEFYKKRFLA 241 >3QAG-A nrPDB Length = 239 Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 40/156 (25%), Positives = 68/156 (43%), Gaps = 12/156 (7%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 78 CP+S R L L+ K + ++ IN+ +KP+W+ P G +PV++ + + +S + Sbjct: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESVIACE 91 Query: 79 LLEEKYPEPSL-----------KTPPEFASVGSKIFGAFVTFLKSKDANDGSEKALVDEL 127 L++ YP L K E S + + L+S + + AL E Sbjct: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRESTNLKAALRQEF 151 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEV 163 LE L+ + F G I+ +D L P L+V Sbjct: 152 SNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDV 187 >3RBT-A nrPDB Length = 246 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 74/158 (46%), Gaps = 15/158 (9%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL----DGKWVADSDVI 76 P+ RVLL LE K++ Y+ + ++ P+WF +P K+PV+++ +++ +S VI Sbjct: 36 PYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLFESVVI 95 Query: 77 VGLLEEKYPEPSLKTPPEFASVGSKI----FGAFVT-FLKSKDAN--DGSEKALVDELEA 129 L+EKY +L + + ++ F + L+ D N GSE+ ++ LE Sbjct: 96 CDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLECFDTNFAFGSEQ-IIQTLEI 154 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAP---KLYHLEVA 164 E L + G + +D + P +LY L Sbjct: 155 FEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLRCV 192 >3WD6-A nrPDB Length = 256 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 11/158 (6%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 78 CP++QR +L L K++ Y+ I++ DKP+W S KVP +++ + + +S V V Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAIEIAEDVTIYESLVTVE 97 Query: 79 LLEEKYPE-PSLKTPPEFASVGSKIFGA-------FVTFLKSKDA-NDGSEKALVDELEA 129 L+E YP+ P L P ++ I A F+ LK D N+ A L+ Sbjct: 98 YLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQSLFIKILKFSDTVNEEHVAAYHKALDF 157 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGH 167 ++ LK F+ G + D + P L A H Sbjct: 158 IQEQLKNRGTVFLDGSEPGYADYMIWPWFERLR-AFAH 194 >1FW1-A nrPDB Length = 216 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 47/158 (29%), Positives = 77/158 (48%), Gaps = 18/158 (11%) Query: 23 SQRVLLTLEEKKLPYKTHLIN-VSDKPQWFLD----ISPEGKVPVVKLDGKWVADSDVIV 77 S RV + L K + YKT IN + D Q F ++P +VP +K+DG + S I+ Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 78 GLLEEKYPEPSL--KTPPEFASVG--SKIFGAFVTFLKS----KDANDG-----SEKALV 124 LEE P P L + P + ASV S + + L++ K + ++ A+ Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAIT 136 Query: 125 DELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 ALE L++ +G + G+++T DL L P++ + E Sbjct: 137 CGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAE 174 >4AGS-A nrPDB Length = 471 Score = 50.8 bits (120), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 20/175 (11%) Query: 16 VLGDCPFSQRVLLTLEEKKLPYKTHLINVSDK-PQWFLDISPEGKVPVVKL---DGKWVA 71 V CPF RV + EK++ Y + + ++ PQW+ I+P VP +++ D +++ Sbjct: 31 VSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADKRFMF 90 Query: 72 DSDVIVGLLEEK-YPEPSL-------KTPPEF--ASVGSKIFGAFVTFLKSKDANDGSEK 121 +S +I L+ P +L + EF A VG I GA L+ D G ++ Sbjct: 91 ESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFI-GAAHGLLR--DPLSGEKR 147 Query: 122 ALVDELEALENHL---KTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV 173 +D+ A + L +GP+ + T D++L P L L+ AL +Y + V Sbjct: 148 KAMDDNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDV 202 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 16/153 (10%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINV--SDKPQWFLDISPEGKVPVVKL-DGKWVADSDVI 76 CPF R L E +K ++ H++ V +P+W+ I+P VP + G+ V +S +I Sbjct: 261 CPFVDRARLASELRK--FQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLI 318 Query: 77 VGLLEEKYPEPSLKTPPEFA----SVGSKI--FGAFVTFLKSKDANDGSEKALVDELEA- 129 V ++ + S P A VG + G FV L S G + + A Sbjct: 319 VQYIDCVATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQWAAG 378 Query: 130 -LENHLKTH---SGPFVAGEKITAVDLSLAPKL 158 LE L H GPF G+++ A D+++ P L Sbjct: 379 ELEQQLAKHPFGEGPFFGGKRMNAGDVAILPFL 411 >2YV7-A nrPDB Length = 260 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 26/111 (23%), Positives = 56/111 (50%), Gaps = 3/111 (2%) Query: 94 EFASVGSKIFGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLS 153 E A++ ++ L KD + AL+ L + +HL + F+ G+ + D Sbjct: 120 EVATLIENLYVKLKLMLVKKD--EAKNNALLSHLRKINDHLSARNTRFLTGDTMCCFDCE 177 Query: 154 LAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFSRESF-ENTKAKKEIV 203 L P+L H+ VA ++ ++ +P LT++ Y ++ ++F ++ A ++I+ Sbjct: 178 LMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDII 228 >2CZ2-A nrPDB Length = 223 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 47/198 (23%), Positives = 92/198 (46%), Gaps = 30/198 (15%) Query: 25 RVLLTLEEKKLPYKTHLIN-VSDKPQWFLD----ISPEGKVPVVKLDGKWVADSDVIVGL 79 RV + L K + Y+ IN + D Q F + ++P +VP +K+DG + S I+ Sbjct: 26 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 85 Query: 80 LEEKYPEPSL--KTPPEFASVG--SKIFGAFVTFLKS---------KDANDGSEKALVDE 126 LEE P P L + P + A V S + + + L++ ++ ++K + Sbjct: 86 LEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSG 145 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE---VALGHYKNWSVPESLTSVRNY 183 ALE L++ +G + G++++ D+ L P++ + E V L Y ++ + Sbjct: 146 FNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY---------PTISHI 196 Query: 184 AKALFSRESFENTKAKKE 201 K L + E F+ + +++ Sbjct: 197 NKELLALEVFQVSHPRRQ 214 >4J2F-A nrPDB Length = 223 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 23/152 (15%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGL 79 PFS RV+ L+ K +PY+ ++ +K L +P K+PV+ GK + +S +I+ Sbjct: 14 PFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILEY 73 Query: 80 LEEKYPE-PSLKTPPEFASV-----------GSKIFGAFVTFLKSKDANDGSEKALVDEL 127 L+E +PE P L + P +V G+ I+ F T + EKA+ + L Sbjct: 74 LDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRT------KGEELEKAVKNCL 127 Query: 128 EAL----ENHLKTHSGPFVAGEKITAVDLSLA 155 E L E+ + + G+KI VD++ Sbjct: 128 EVLKTIEEHAMGVSDDKYFGGDKIGIVDIAFC 159 >1E6B-A nrPDB Length = 221 Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 22/158 (13%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVA-DSDVIVG 78 + RV + L K L Y+ +N+ Q+ F I+P G VP + +DG V DS I+ Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPAL-VDGDVVINDSFAIIM 78 Query: 79 LLEEKYPEPSL------KTPPEFASVGSKIFG-------AFVTFLKSK----DANDGSEK 121 L+EKYPEP L K + ++ + G A + +++ K + Sbjct: 79 YLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAWVNN 138 Query: 122 ALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLY 159 A+ ALE L +G G++I DL LAP+++ Sbjct: 139 AITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIH 176 >3UBL-A nrPDB Length = 242 Score = 43.5 bits (101), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 18/147 (12%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 + +V L + EK L Y+ I S + + FL ISP GK+PV+++DGK++ +S I+ L+ Sbjct: 14 YVNKVKLGILEKGLEYEQIRIAPSQE-EDFLKISPMGKIPVLEMDGKFIFESGAILEFLD 72 Query: 82 EKYPEPSLKTP--PEFASVGSKIFGAFVTFLK-------------SKDANDGSEKALVDE 126 +P+ P P A+ +I T+L S + + LV Sbjct: 73 TIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEIVEEVHSTLVKG 132 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLS 153 ++AL+ ++ P++AG T D S Sbjct: 133 IKALQRVVRF--SPYIAGNVFTLADCS 157 >5ECL-B nrPDB Length = 223 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 15/196 (7%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGLL 80 F R + L EK + ++ + S+K L +P K+PV+ +GK V +S +V + Sbjct: 21 FGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYV 80 Query: 81 EEKYPEPSLKTPPE-FASVGSKIFGAFV----------TFLKSKDANDGSEKALVDELEA 129 +E +PE + P + + ++ + FV + K + + +K ++ ++ Sbjct: 81 DEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKI 140 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 LE+ L P+ G+ VD+SL + A + N+S+ + +AK Sbjct: 141 LESELGDK--PYFGGDSFGYVDISLITFSSWFQ-AYEKFGNFSIESESPKLIAWAKRCME 197 Query: 190 RESFENTKAKKEIVVA 205 +ES + E +VA Sbjct: 198 KESVSKSLPDSEKIVA 213 >4CHS-A nrPDB Length = 219 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 38/151 (25%), Positives = 74/151 (49%), Gaps = 20/151 (13%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGL 79 PF RV + L EK + Y+ ++ +K L ++P K+PV+ +GK +++S + V Sbjct: 14 PFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISESLIAVQY 73 Query: 80 LEEKYPE--PSLKTPPEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDEL 127 +EE + + P L + P + ++ + +V + + + ++K ++ L Sbjct: 74 IEEVWNDRNPLLPSDP-YQRAQARFWADYVDIKIHDLGKKIWTSKGEEKEAAKKEFIEAL 132 Query: 128 EALENHL--KTHSGPFVAGEKITAVDLSLAP 156 + LE L KT+ G G+ I VD++L P Sbjct: 133 KLLEEQLGDKTYFG----GDNIGFVDIALVP 159 >2VO4-A nrPDB Length = 219 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 15/184 (8%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGL 79 PF RV + L EK + Y+ ++ +K L ++P K+PV+ +GK + +S + V Sbjct: 14 PFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICESLIAVQY 73 Query: 80 LEEKY--------PEPSLKTPPEFAS--VGSKIFGAFVTFLKSK-DANDGSEKALVDELE 128 +EE + +P + F + V KI+ SK + + ++K ++ L+ Sbjct: 74 IEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAKKEFIEALK 133 Query: 129 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 LE L + + G+ + VD++L P Y A + ++ +AK Sbjct: 134 LLEEQLGDKT--YFGGDNLGFVDIALVP-FYTWFKAYETFGTLNIESECPKFIAWAKRCL 190 Query: 189 SRES 192 +ES Sbjct: 191 QKES 194 >4IGJ-A nrPDB Length = 242 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 23/159 (14%) Query: 25 RVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKL--DGK--WVADSDVIV 77 RV L L K L Y+ +++ + Q+ +P +VPV+++ DG+ + S I+ Sbjct: 38 RVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMAIL 97 Query: 78 GLLEEKYPEPSLKTPPEFASVGSKIFGAFVT-------------FLKSKDANDGSEKA-- 122 LEE++PEP+L P + + V L+ K E A Sbjct: 98 EWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPGWDREWARF 157 Query: 123 -LVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYH 160 + L ALE ++ +G F G+ T D L P+LY+ Sbjct: 158 FIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYN 196 >6EP7-A nrPDB Length = 220 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 41/183 (22%), Positives = 85/183 (46%), Gaps = 15/183 (8%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGLL 80 + R + LEEKK+ Y+ ++S+K L ++P K+PV+ +GK + +S + V + Sbjct: 15 YGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVLIHEGKPICESIIQVQYI 74 Query: 81 EEKYPE--PSLKTPPEFASVGSKIFGAFV---TFLKSK----DANDGSEKALVDELEALE 131 +E +P+ P L + P + ++ + ++ T++ K ++ + E A ++ +E L+ Sbjct: 75 DELWPDTNPILPSDP-YQRAQARFWADYIDKKTYVPCKALWSESGEKQEAAKIEFIEVLK 133 Query: 132 NHLKTHSGP--FVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 L + G + G + VD++ Y N S+ + +A+ Sbjct: 134 T-LDSELGDKYYFGGNEFGLVDIAFI-GFYSWFRTYEEVANLSIVLEFPKLMAWAQRCLK 191 Query: 190 RES 192 RES Sbjct: 192 RES 194 >4PNG-A nrPDB Length = 229 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 22/167 (13%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADS 73 L P + V LTL ++PY+ +N K + FL +P+ VP ++ DG ++ DS Sbjct: 15 LEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDS 74 Query: 74 DVIVGLLEEKYPEPSLKTPPEF---ASVGSKI-FGAFVTF---LKS--------KDANDG 118 I+ L KY + P + A V ++ F + V F L+S K Sbjct: 75 HAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIP 134 Query: 119 SEK--ALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEV 163 E+ A+++ + LE L + +VAG ++T D S+ + LEV Sbjct: 135 KERYDAIIEVYDFLEKFLAGND--YVAGNQLTIADFSIISTVSSLEV 179 >4YH2-A nrPDB Length = 222 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 22/166 (13%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADS 73 L P + V LTL L Y+ +++ + Q +L+ +P+ VP ++ DG ++ DS Sbjct: 9 LDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDS 68 Query: 74 DVIVGLLEEKYPEPSL---KTPPEFASVGSKI-FGAFVTF---LKSKDAN---DGSEK-- 121 I+ L KY + K P + A V ++ F + V F ++S + G K Sbjct: 69 HAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVP 128 Query: 122 -----ALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 A+++ + +E LK ++AG ++T D SL + LE Sbjct: 129 KERYDAIIEIYDFVETFLKGQD--YIAGNQLTIADFSLVSSVASLE 172 >1JLV-A nrPDB Length = 209 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 18/133 (13%) Query: 47 KPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSL---KTPPEFASVGSKIF 103 KP+ FL I+P+ +P + +G + +S I L EKY + K P + A V +++ Sbjct: 40 KPE-FLKINPQHCIPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLY 98 Query: 104 GAFVTFLKS------------KDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVD 151 T + + AN +EK + D ++ L L H +VAG+ +T D Sbjct: 99 FDMGTLYQRFADYYYPQIFAKQPANAENEKKMKDAVDFLNTFLDGHK--YVAGDSLTIAD 156 Query: 152 LSLAPKLYHLEVA 164 L++ + +VA Sbjct: 157 LTVLATVSTYDVA 169 >3UAR-A nrPDB Length = 227 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 15/119 (12%) Query: 51 FLDISPEGKVPVVKL-DGKWVADSDVIVGLLEEKYPEPSLKTPPE----------FASVG 99 FL ++P+G VP ++L DG+ + + VI+ L + PE L P A + Sbjct: 45 FLQVNPKGYVPALQLDDGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFIS 104 Query: 100 SKIFGAFVTFLKSKDANDGSEKA---LVDELEALENHLKTHSGPFVAGEKITAVDLSLA 155 ++I F F + + A L L+ +E+ L+ GP++ G++ + D L+ Sbjct: 105 TEIHKTFGPFWNPESPEASKQIALGLLSRRLDYVEDRLEA-GGPWLMGDRYSVADAYLS 162 >2PMT-A nrPDB Length = 203 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 7/82 (8%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSDKP----QWFLDISPEGKVPVVKLD-GKWVAD 72 G C S ++L E L + I++ K + FL I+P+G+VPV++LD G + + Sbjct: 8 GSCSLSPHIVL--RETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTE 65 Query: 73 SDVIVGLLEEKYPEPSLKTPPE 94 IV L + P+ +L PP+ Sbjct: 66 GVAIVQYLADLKPDRNLIAPPK 87 >1OYJ-A nrPDB Length = 231 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGL 79 PF QR + + EK L ++ ++ +K L +P K+PV+ G+ V++S VI+ Sbjct: 16 PFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLHAGRPVSESLVILQY 75 Query: 80 LEEKYPEPSLKTPP 93 L++ +P PP Sbjct: 76 LDDAFPGTPHLLPP 89 >3VWX-A nrPDB Length = 222 Score = 35.4 bits (80), Expect = 0.019, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 22/155 (14%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADSDVI 76 P + LLTL+ LP++ ++N+ K +L +P+ VP ++ DG + DS I Sbjct: 12 SPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDSHAI 71 Query: 77 VGLLEEKYPEPSLKTPPEF---ASVGSKIF--------------GAFVTFLKSKDANDGS 119 + L KY + P + A V +++ A + F Sbjct: 72 MAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIPQHQ 131 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSL 154 ++V+ LE+ LK + ++AG+ +T D S+ Sbjct: 132 IDSIVESYGFLESFLKNNK--YMAGDHLTIADFSI 164 >3NIV-A nrPDB Length = 222 Score = 35.4 bits (80), Expect = 0.020, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 5/70 (7%) Query: 25 RVLLTLEEKKLPYK---THLINVSDKPQ--WFLDISPEGKVPVVKLDGKWVADSDVIVGL 79 RV + L KK+ Y+ HL+N + + I+P+ VP + ++G+ ++ S I+ Sbjct: 16 RVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQILSQSMAIIDY 75 Query: 80 LEEKYPEPSL 89 LEE +PE L Sbjct: 76 LEEIHPEMPL 85 >3PR8-A nrPDB Length = 229 Score = 34.3 bits (77), Expect = 0.040, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 + V L L EK L ++ PQ L++SP GKVPV++ + +++++ VI+ +E Sbjct: 13 YYNMVKLALLEKGLTFEEVTFYGGQAPQA-LEVSPRGKVPVLETEHGFLSETSVILDYIE 71 Query: 82 E 82 + Sbjct: 72 Q 72 >1PN9-A nrPDB Length = 209 Score = 33.9 bits (76), Expect = 0.048, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 18/133 (13%) Query: 47 KPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSL---KTPPEFASVGSKIF 103 KP+ FL ++P+ +P + +G + +S I L EKY + K P + A V +++ Sbjct: 40 KPE-FLKLNPQHCIPTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLY 98 Query: 104 GAFVTFLKS------------KDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVD 151 T + + AN +EK + D + L L+ + AG +T D Sbjct: 99 FDMGTLYQRFADYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQE--YAAGNDLTIAD 156 Query: 152 LSLAPKLYHLEVA 164 LSLA + EVA Sbjct: 157 LSLAATIATYEVA 169 >2JL4-A nrPDB Length = 213 Score = 33.9 bits (76), Expect = 0.050, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 23 SQRVLLTLEEKKLPYK---THLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGL 79 S R+ + L K +PY+ HL F ++P+ VP + + + S I+ Sbjct: 13 SHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQVLIQSPAIIEW 72 Query: 80 LEEKYPEPSL 89 LEE+YP P+L Sbjct: 73 LEEQYPTPAL 82 >4RI7-A nrPDB Length = 215 Score = 33.5 bits (75), Expect = 0.074, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 9/78 (11%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINV------SDKPQWFLDISPEGKVPVVKLDGKWVADS 73 C RVL TL EK +P+ HLI + KP+ +L I P G+VP K + + +S Sbjct: 13 CTAVSRVLATLIEKDVPF--HLIPIDLSKGEQKKPE-YLKIQPFGQVPAFKDESITLFES 69 Query: 74 DVIVGLLEEKYPEPSLKT 91 I + +KY + K+ Sbjct: 70 RAICRYICDKYADKGNKS 87 >3M8N-A nrPDB Length = 225 Score = 33.1 bits (74), Expect = 0.083, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 25/154 (16%) Query: 23 SQRVLLTLEEKKLPYKTHLINV----SDKPQWFLDISPEGKVPVVKLD-GKWVADSDVIV 77 S +V L L PY+ +++ S P FL +P G+VP+++ G+++A+S+ I+ Sbjct: 15 SYKVRLALALLDAPYRAVEVDILRGESRTPD-FLAKNPSGQVPLLETAPGRYLAESNAIL 73 Query: 78 GLL---EEKYPEPSLKTPP-------EFASVGSKIFGAFVTFLKSKDANDGSEKALVDEL 127 L P+ + E ++ I A+ K D AL D L Sbjct: 74 WYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQTHALEDWL 133 Query: 128 E-------ALENHLKTHSGPFVAGEKITAVDLSL 154 E +ENHLKT+ + A ++T D++L Sbjct: 134 ERGYAALQVMENHLKTND--YFAAGQLTIADIAL 165 >4MPF-A nrPDB Length = 266 Score = 33.1 bits (74), Expect = 0.095, Method: Compositional matrix adjust. Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 26/150 (17%) Query: 41 LINVSDKPQWFLDISPEGKVPVVKLDGKWV-ADSDVIVGLLEEKYPEPSLKTPPEFASVG 99 L+ K + FL I+ GK+P +K DG ++ +S I+ L KY P P + + Sbjct: 57 LVKGQHKSKEFLQINSLGKLPTLK-DGDFILTESSAILIYLSCKYQTPDHWYPSDLQARA 115 Query: 100 S----------------------KIFGAFVTFLKSKDANDGSEKALVDELEALENHLKTH 137 ++ G + K+ + + A+ L+ LE+ Sbjct: 116 RVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKF-LG 174 Query: 138 SGPFVAGEKITAVDLSLAPKLYHLEVALGH 167 PF+AG+++T DL +L VALG+ Sbjct: 175 DRPFLAGQQVTLADLMALEELMQ-PVALGY 203 >3TOT-A nrPDB Length = 226 Score = 33.1 bits (74), Expect = 0.096, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVGL 79 P++++V + L EKK+ Y+ L +V + +P GKVP + + DG + DS VI Sbjct: 12 PYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIAEY 71 Query: 80 LEEKYPEPSLKTP 92 + P L P Sbjct: 72 ADTLSPVARLIPP 84 >5EY6-A nrPDB Length = 217 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 31/165 (18%) Query: 25 RVLLTLEEKKLPYKTHLINVS----DKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLL 80 RVL+TL EK +P++ +++S KP +L I P G+VP + + + +S I + Sbjct: 17 RVLVTLLEKDVPFQIIPVDMSKGEHKKPD-YLKIQPFGQVPAFQDESISLFESRSICRYV 75 Query: 81 EEKYPEPSLK-----TPPEFASVGSKIFGAFVTFLKSKDA---------------NDG-- 118 EKY + K P E AS+ + +F S A + G Sbjct: 76 CEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVI 135 Query: 119 --SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHL 161 +E+ L L+ E L F+AG++ T DLS P +L Sbjct: 136 KQNEEKLGKVLDIYEQRLGESR--FLAGDEFTFADLSHLPNGDYL 178 >5ZWP-A nrPDB Length = 208 Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust. Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 25/167 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSD----KPQWFLDISPEGKVPVVKLDGKW-VAD 72 G P + VL+T + + L+N+ KP+ FL I+P+ +P + +DG + + + Sbjct: 8 GSAP-CRSVLMTAKALGIELNKKLLNLQAGEHLKPE-FLKINPQHTIPTL-VDGDFALWE 64 Query: 73 SDVIVGLLEEKYPEP-SL--KTPPEFASVGSKIFGAFVTFLKS------------KDAND 117 S I+ L EKY + SL K P + A + +++ T KS A+ Sbjct: 65 SRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPADP 124 Query: 118 GSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVA 164 K + + L LK H + AG+ +T DL+L + EVA Sbjct: 125 ELFKKIETAFDFLNTFLKGHE--YAAGDSLTVADLALLASVSTFEVA 169 >4IKH-A nrPDB Length = 244 Score = 32.3 bits (72), Expect = 0.14, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 3/47 (6%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVV 63 P +V + LEE LPY+ H ++ + Q FL +SP K+P + Sbjct: 30 TPNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAI 76 >2VCT-A nrPDB Length = 222 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 11/115 (9%) Query: 59 KVPVVKLDGKWVADSDVIVGLLEEKY----PEPSLKTPPEFASVGSKIFGAFVTFLKSKD 114 +VP+V++DG + + I+ + KY + K + G G + L Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQ 113 Query: 115 ANDGSEK-ALVDE------LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 + K AL+ E A E LK+H ++ G K++ D+ L LY++E Sbjct: 114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >3M3M-A nrPDB Length = 210 Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust. Identities = 37/157 (23%), Positives = 70/157 (44%), Gaps = 25/157 (15%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINV---SDKPQWFLDISPEGKVPVVKL-DGKWVADS 73 G+C ++ L L LPY+ +++ + + FL +P GK+PV++L DG + +S Sbjct: 13 GNC---YKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDGTCLWES 69 Query: 74 DVIVGLLEEKYP----EPSLKTP----PEFASVGSKIFGAFVTFLKSKDA--NDGSEKAL 123 + I+ L + EP L+T F + + A F++ + + E+ L Sbjct: 70 NAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGLPEERREEYL 129 Query: 124 ------VDELEALENHLKTHSGPFVAGEKITAVDLSL 154 L+ +E L P++ GE + D++L Sbjct: 130 KLHKRGYKALDVMEKQLS--RTPYLVGEHYSIADIAL 164 >2VCV-A nrPDB Length = 222 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 11/115 (9%) Query: 59 KVPVVKLDGKWVADSDVIVGLLEEKY----PEPSLKTPPEFASVGSKIFGAFVTFL---- 110 +VP+V++DG + + I+ + KY + + + + G + L Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCR 113 Query: 111 -KSKDANDG--SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 + KDA EK A E L++H ++ G K++ D+SL LY++E Sbjct: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVE 168 >3I6A-A nrPDB Length = 222 Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust. Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 13/116 (11%) Query: 59 KVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKI-----FGAFVTFL--- 110 +VP+V++DG + + I+ + KY K E A + I G + L Sbjct: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYG-KDIKERALIDMYIEGIADLGEMIIMLPFC 112 Query: 111 --KSKDANDG--SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 + KDA EK A E LK+H ++ G K++ D+ L LY++E Sbjct: 113 PPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >6F05-A nrPDB Length = 215 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 30/160 (18%) Query: 24 QRVLLTLEEKKLPYKT---HLINVSDKPQWFLDISPEGKVPVVKLDGKW-VADSDVIVGL 79 +R L+TL EK + ++T L+ K +L + P G VP V +DG + + +S ++ Sbjct: 14 KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAV-VDGDYKIFESRAVMRY 72 Query: 80 LEEKYP-----------------------EPSLKTPPEFASVGSKIFGAFVTFLKSKDAN 116 + EKY E + PP +F + + F + Sbjct: 73 VAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLI 132 Query: 117 DGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAP 156 SE+ L L+ E HL ++AG+ ++ DL+ P Sbjct: 133 KESEEKLAGVLDVYEAHLS--KSKYLAGDFVSLADLAHLP 170 >2YV9-A nrPDB Length = 291 Score = 31.2 bits (69), Expect = 0.35, Method: Compositional matrix adjust. Identities = 14/90 (15%), Positives = 40/90 (44%) Query: 123 LVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRN 182 + ++L ++ L ++ G +T D L P+L+H+ + + +P + T + Sbjct: 164 VCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWA 223 Query: 183 YAKALFSRESFENTKAKKEIVVAGWESKVN 212 Y + +F + + ++ ++ ++N Sbjct: 224 YILTAYRTAAFIESCPADQDIIHHYKEQMN 253 >4MK3-A nrPDB Length = 226 Score = 31.2 bits (69), Expect = 0.39, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVI 76 P++++V + L EKK+ Y+ NV +P GKVP + + DG V DS VI Sbjct: 32 PYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAVFDSRVI 88 >4M2B-A nrPDB Length = 505 Score = 30.8 bits (68), Expect = 0.41, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%) Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALG 166 LE ++ H T P + EK S +PK+Y LE A+G Sbjct: 318 LETMQEHGGTLPLPVIRNEKTVDSSNSASPKVYQLETAMG 357 >5NR1-A nrPDB Length = 228 Score = 30.8 bits (68), Expect = 0.47, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 4/73 (5%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVV----KLDGKWVADSDVI 76 P S++V L L EK+LP+ + + P F ++P G PV+ + ++ I Sbjct: 14 PASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRAI 73 Query: 77 VGLLEEKYPEPSL 89 + +EE EP L Sbjct: 74 LEHIEETETEPPL 86 >2GDR-A nrPDB Length = 202 Score = 30.8 bits (68), Expect = 0.49, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 22/155 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSDKP----QWFLDISPEGKVPVVKL-DGKWVAD 72 G C S + L E L ++ ++++ K Q +L+++P G VP ++L DG+ + + Sbjct: 8 GACSLSPHI--ALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTE 65 Query: 73 SDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGS---EKALVDELE- 128 IV + ++ P L P S ++ F+ S+ S A DE + Sbjct: 66 GPAIVQYVADQVPGKQLA--PANGSFERYHLQQWLNFISSELHKSFSPLFNPASSDEWKN 123 Query: 129 ALENHLKTHSG---------PFVAGEKITAVDLSL 154 A+ L T G P++ G++++ D+ L Sbjct: 124 AVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYL 158 >1PL2-A nrPDB Length = 222 Score = 30.8 bits (68), Expect = 0.50, Method: Compositional matrix adjust. Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 13/116 (11%) Query: 59 KVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKI-----FGAFVTFL--- 110 +VP+V++DG + I+ + KY K E A + I G + L Sbjct: 54 QVPMVEIDGMKLVQERAILNYIASKYNLYG-KDIKERALIDMYIEGIADLGEMILLLPVC 112 Query: 111 --KSKDANDG--SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 + KDA EK A E LK+H ++ G K++ D+ L LY++E Sbjct: 113 PPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >1F3B-A nrPDB Length = 222 Score = 30.4 bits (67), Expect = 0.66, Method: Compositional matrix adjust. Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 15/117 (12%) Query: 59 KVPVVKLDGKWVADSDVIVGLLEEKY----PEPSLKTPPEFASVG----SKIFGAFVTFL 110 +VP+V++DG +A + I+ + KY + + + S G +++ G V L Sbjct: 53 QVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLV--L 110 Query: 111 KSKDANDGSEKALVDE-----LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 D + D L A E LK+H ++ G ++T VD+ L L ++E Sbjct: 111 CPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVE 167 >1F2E-A nrPDB Length = 201 Score = 30.0 bits (66), Expect = 0.76, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 18/119 (15%) Query: 51 FLDISPEGKVPVVKLD-GKWVADSDVIVGLLEEKYPEPSLKTPPE-----------FASV 98 FL ++P GKVP + LD G+ + ++ I+ + ++ P L P E + + Sbjct: 43 FLTVNPSGKVPALTLDSGETLTENPAILLYIADQNPASGL-APAEGSLDRYRLLSRLSFL 101 Query: 99 GSKIFGAFVTFL---KSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSL 154 GS+ AFV S +A + +++ + L AL+ L AG + D+ L Sbjct: 102 GSEFHKAFVPLFAPATSDEAKAAAAESVKNHLAALDKELAGRD--HYAGNAFSVADIYL 158 >1KHW-A nrPDB Length = 516 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 10/104 (9%) Query: 74 DVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFL-KSKDANDGSEKALVDELEALEN 132 ++ V L+ EP L EF + ++ FL K + + + KA + L+ Sbjct: 66 NIAVKNLQVYQQEPKLDKVDEFIERAAADVLGYLRFLTKGERQANLNFKAAFNTLD---- 121 Query: 133 HLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPES 176 L T GPFV G+KI V + ++ +A YK WSV S Sbjct: 122 -LSTSCGPFVPGKKIDHVKDGVMDQV----LAKHLYKCWSVANS 160 >3MAK-A nrPDB Length = 209 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 40/166 (24%), Positives = 72/166 (43%), Gaps = 23/166 (13%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSD----KPQWFLDISPEGKVPVVKLDGKWVADS 73 G P + V++T + + L+N+ KP+ FL I+P+ +P + +G + +S Sbjct: 9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPE-FLKINPQHTIPTLVDNGFALWES 66 Query: 74 DVIVGLLEEKYPEP-SL--KTPPEFASVGSKIFGAFVTFLKS------------KDANDG 118 I L EKY + SL K P + A + +++ T +S A+ Sbjct: 67 RAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPE 126 Query: 119 SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVA 164 + K + E L L+ + AG+ +T D++L + EVA Sbjct: 127 AFKKIEAAFEFLNTFLEGQD--YAAGDSLTVADIALVATVSTFEVA 170 >5F06-A nrPDB Length = 216 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 7/76 (9%) Query: 12 GAPDVLGDCPFSQRVLLTLEEKKLPYK---THLINVSDKPQWFLDISPEGKVPVVKLDGK 68 GAP + C + RVL L EK L ++ L K FL +P G++P ++ D Sbjct: 6 GAP--MSTC--TSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 69 WVADSDVIVGLLEEKY 84 + +S I + EK+ Sbjct: 62 TLFESRAITSYIAEKF 77 >1EXZ-A nrPDB Length = 141 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 20/35 (57%) Query: 83 KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAND 117 K PEP L TP EF + ++ AF F+ + + +D Sbjct: 103 KSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSD 137 >2CA8-A nrPDB Length = 211 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 21/157 (13%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG-----KWVADSDVIV 77 ++ + +TL + Y+ I+ D P+ I P G++P VK+ KW+ +S I Sbjct: 17 AESIRMTLVAAGVNYEDERISFQDWPKIKPTI-PGGRLPAVKITDNHGHVKWMVESLAIA 75 Query: 78 GLLEEKYPEPSLKTPPEFASVGSKIFGA--------FVTFLKSKDANDGSEKALVDE--- 126 + +K+ T E+ +V K+ G + T +K ++ K +++ Sbjct: 76 RYMAKKHHMMG-GTEEEYYNV-EKLIGQAEDLEHEYYKTLMKPEEEKQKIIKEILNGKVP 133 Query: 127 --LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHL 161 L+ + LK +G G+K+T DL L + H+ Sbjct: 134 VLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHV 170 >3R2Q-A nrPDB Length = 202 Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 44/208 (21%) Query: 21 PFSQRVLLTLEEK--------KLPYKTHLINVSDKPQWFLDISPEGKVPV-VKLDGKWVA 71 PF +++ + L EK +LPY N + F +P GKVPV V +G+ Sbjct: 10 PFVRKLSILLLEKGITFEFINELPY-----NADNGVAQF---NPLGKVPVLVTEEGECWF 61 Query: 72 DSDVIVGLLEEKYPEPSL--KTPPE------FASVGSKIFGAFVTFLK--SKDANDGSEK 121 DS +I +E P++ + P E ++ I A + ++ ++ A SE Sbjct: 62 DSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSED 121 Query: 122 ALVDELEALENHLKTHSGPFVAGE-KITAVDLSLAPKLYHLEVALGHYK------NWSV- 173 L+ + E + L G V G K V+L+ + A+G+ W V Sbjct: 122 ELLRQREKINRSLDVLEGYLVDGTLKTDTVNLAT----IAIACAVGYLNFRRVAPGWCVD 177 Query: 174 -PESLTSVRNYAKALFSRESFENTKAKK 200 P + V N LFSRESF T+ K Sbjct: 178 RPHLVKLVEN----LFSRESFARTEPPK 201 >1SCF-A nrPDB Length = 273 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 20/35 (57%) Query: 83 KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAND 117 K PEP L TP EF + ++ AF F+ + + +D Sbjct: 128 KSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSD 162 >1CEM-A nrPDB Length = 363 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 13/92 (14%) Query: 90 KTPPEFASVGSKIFGAFVTFLKSKDANDGSEKALVDEL-----EALENHLKTHSGPFVAG 144 +T +++ G + A L A DG+ K +VD + NH + GP VA Sbjct: 253 RTAVDYSWFGDQRAKANCDMLTKFFARDGA-KGIVDGYTIQGSKISNNHNASFIGP-VAA 310 Query: 145 EKITAVDLSLAPKLYHLEVAL------GHYKN 170 +T DL+ A +LY VA+ G+Y N Sbjct: 311 ASMTGYDLNFAKELYRETVAVKDSEYYGYYGN 342 >3UAN-A nrPDB Length = 269 Score = 28.1 bits (61), Expect = 3.1, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 5/86 (5%) Query: 90 KTPPEFAS--VGSKIFGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKI 147 KTP F S V +I T D SE+ L D + L NHL+ H P+ E + Sbjct: 81 KTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHK-PYPPIEDL 139 Query: 148 TAVD--LSLAPKLYHLEVALGHYKNW 171 D L+L K + + H NW Sbjct: 140 LMRDGRLNLDYKALNRSLYHAHMLNW 165 >6JWK-A nrPDB Length = 222 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQWF---LDISPEGKVP-VVKLDGKWVADSDVIVG 78 S RV + L K L Y+ +N+ Q +P G +P +V DG+ + S I+ Sbjct: 12 SYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSLAIID 71 Query: 79 LLEEKYPEPSL 89 L+ PEP L Sbjct: 72 YLDAVQPEPRL 82 >3GH6-A nrPDB Length = 210 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 38/174 (21%), Positives = 74/174 (42%), Gaps = 22/174 (12%) Query: 18 GDCPFSQRVLLTLEEKKLPY-KTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADS 73 G P + VL+T + + + K +IN + Q+ +L I+P+ +P + G + +S Sbjct: 8 GSAP-CRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWES 66 Query: 74 DVIVGLLEEKYPEPSLKTPPEF---ASVGSKIFGAFVTFLKS------------KDANDG 118 I+ L EKY + P + A + +++ T KS K AN+ Sbjct: 67 RAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFLKKPANEE 126 Query: 119 SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWS 172 + K + E L L+ + + AG + D++ + +VA +K ++ Sbjct: 127 NYKKIEVAFEFLNTFLEGQT--YSAGGDYSLADIAFLATVSTFDVAGFDFKRYA 178 >5N8X-A nrPDB Length = 481 Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 20/91 (21%) Query: 126 ELEALENHLKT----------HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPE 175 + EAL+ H K+ FV G IT D++ + +H++ G YK + Sbjct: 349 DFEALKPHFKSLGQTITPADKSDKGFVLGHSIT--DVTFLKRHFHMDYGTGFYKPVMASK 406 Query: 176 SLTSVRNYAKALFSRESFENTKAKKEIVVAG 206 +L ++ ++A+ T +K I VAG Sbjct: 407 TLEAILSFAR--------RGTIQEKLISVAG 429 >4D10-E nrPDB Length = 334 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 3/48 (6%) Query: 67 GKWVADSDVIVGLLEEKYPEPSLKT---PPEFASVGSKIFGAFVTFLK 111 G W++ DV +L +++ EP + P S G GAF T+ K Sbjct: 144 GCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPK 191 >3QMX-A nrPDB Length = 99 Score = 27.3 bits (59), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGK--VPVVKLDGKWVADSDVIV 77 CPF R L L+ K + ++ + I+ ++ + + GK +P + +D + + D I Sbjct: 26 CPFCMRALALLKRKGVEFQEYCIDGDNEAREAMAARANGKRSLPQIFIDDQHIGGCDDIY 85 Query: 78 GL 79 L Sbjct: 86 AL 87 >4F7O-A nrPDB Length = 257 Score = 27.3 bits (59), Expect = 5.6, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 3/48 (6%) Query: 67 GKWVADSDVIVGLLEEKYPEPSLKT---PPEFASVGSKIFGAFVTFLK 111 G W++ DV +L +++ EP + P S G GAF T+ K Sbjct: 144 GCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPK 191 >2IL3-A nrPDB Length = 221 Score = 27.3 bits (59), Expect = 5.6, Method: Compositional matrix adjust. Identities = 44/145 (30%), Positives = 63/145 (43%), Gaps = 29/145 (20%) Query: 28 LTLEEKKLPYKT--HLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKY- 84 L LE+K + T HL KP+ F+ ++P+ +PV+ +G + +S I+ L KY Sbjct: 27 LELEQKTINLLTGDHL-----KPE-FVKLNPQHTIPVLDDNGTIITESHAIMIYLVTKYG 80 Query: 85 PEPSL--KTPPEFASVGSK--------------IFGAFVTFLKSKDANDGSEKALVDELE 128 + SL K P + A V S IF + F KS D E + E Sbjct: 81 KDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPEDRVE-YVQKSYE 139 Query: 129 ALENHLKTHSGPFVAGEKITAVDLS 153 LE+ L FVAG +T D S Sbjct: 140 LLEDTL---VDDFVAGPTMTIADFS 161 >1U3I-A nrPDB Length = 211 Score = 27.3 bits (59), Expect = 5.6, Method: Compositional matrix adjust. Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 21/157 (13%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG-----KWVADSDVIV 77 ++ + +TL + Y+ I+ D P+ I P G++P VK+ KW+ +S I Sbjct: 17 AESIRMTLVAAGVDYEDERISFQDWPKIKPTI-PGGRLPAVKVTDDHGHVKWMLESLAIA 75 Query: 78 GLLEEKYPEPSLKTPPEFASVGSKIFGA--------FVTFLKSKDANDGSEKALVDE--- 126 + +K+ +T E+ SV K+ G T +K ++ + K +++ Sbjct: 76 RYMAKKHHMMG-ETDEEYYSV-EKLIGQAEDVEHEYHKTLMKPQEEKEKITKEILNGKVP 133 Query: 127 --LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHL 161 + LK +G G+K+T DL L + H+ Sbjct: 134 VLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHV 170 >1YQ1-A nrPDB Length = 208 Score = 26.9 bits (58), Expect = 6.2, Method: Compositional matrix adjust. Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 25/136 (18%) Query: 49 QWFLDI---SPEGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGS--KIF 103 Q +LDI +P ++PV+ +DG + S I+ L K+ KTP E A V + +F Sbjct: 38 QTWLDIKDSTPMKQLPVLNIDGFELPQSGAILRYLARKFGFAG-KTPEEEAWVDAVHDLF 96 Query: 104 GAFVTFLKSKDANDGSEKALVDELEALENHL-----------------KTHSGPFVAGEK 146 F+ K A S K+ +E+E + K++SG F+ G Sbjct: 97 KDFLAEFKKFAAERRSGKS-AEEVEKFRSEFFLPARNTYFNILNGLLEKSNSG-FLIGSD 154 Query: 147 ITAVDLSLAPKLYHLE 162 IT DL + L L+ Sbjct: 155 ITFADLVVVDNLLTLK 170 >2O26-A nrPDB Length = 145 Score = 26.9 bits (58), Expect = 7.0, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 19/35 (54%) Query: 83 KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAND 117 K PE TP EF S+ ++ AF F+ + D +D Sbjct: 101 KRPETRSFTPEEFFSIFNRSIDAFKDFMVASDTSD 135 >1ZRH-A nrPDB Length = 274 Score = 26.6 bits (57), Expect = 8.7, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 15/91 (16%) Query: 90 KTPPEFAS--VGSKIFGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKI 147 KTP F S V +++ + D SE+ L D + NH++ H P+ + E+ Sbjct: 86 KTPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHK-PYPSIEEF 144 Query: 148 TAVD-------LSLAPKLYHLEVALGHYKNW 171 D +L LYH+ H +NW Sbjct: 145 LVRDGRLNVDYKALNRSLYHV-----HMQNW 170 >5YHP-A nrPDB Length = 355 Score = 26.6 bits (57), Expect = 8.7, Method: Compositional matrix adjust. Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 10/51 (19%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDI----SPEGKVPVVKLDG 67 PF+ L + PYKTHL+ VS P L I +P+GK PVV L G Sbjct: 34 PFTMTSLFAAIQ---PYKTHLLRVS--PLHRLSIKEYGNPQGK-PVVFLHG 78 >1WP9-A nrPDB Length = 494 Score = 26.6 bits (57), Expect = 9.0, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Query: 158 LYH-LEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEI 202 LYH + + L H + L+++R Y K L+ +TKA KEI Sbjct: 274 LYHAMALKLHHAIELLETQGLSALRAYIKKLYEEAKAGSTKASKEI 319 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5LOL-A nrPDB 298 2e-81 5ELG-A nrPDB 296 6e-81 5IQY-A nrPDB 291 1e-79 5D9W-A nrPDB 288 1e-78 5N9U-A nrPDB 286 6e-78 5Y7I-A nrPDB 215 1e-56 2R5G-A nrPDB 207 3e-54 4K0G-A nrPDB 206 6e-54 2D2Z-A nrPDB 206 9e-54 2VO4-A nrPDB 197 2e-51 5J5N-A nrPDB 196 6e-51 4CHS-A nrPDB 191 2e-49 5ECL-B nrPDB 188 1e-48 3FY7-A nrPDB 188 2e-48 3QAG-A nrPDB 171 2e-43 4PQI-A nrPDB 167 3e-42 4QQ7-A nrPDB 167 5e-42 2CZ2-A nrPDB 164 3e-41 4J2F-A nrPDB 161 2e-40 3LFL-A nrPDB 160 5e-40 1FW1-A nrPDB 156 5e-39 3WD6-A nrPDB 155 2e-38 2YV7-A nrPDB 154 2e-38 4IGJ-A nrPDB 148 2e-36 4AGS-A nrPDB 148 2e-36 3RBT-A nrPDB 145 1e-35 1E6B-A nrPDB 142 9e-35 3UBL-A nrPDB 116 1e-26 Sequences not found previously or not previously below threshold: 5G5A-A nrPDB 175 1e-44 6EP7-A nrPDB 165 2e-41 1OYJ-A nrPDB 124 3e-29 1GWC-A nrPDB 115 1e-26 2JL4-A nrPDB 105 1e-23 3NIV-A nrPDB 104 4e-23 3LG6-A nrPDB 100 8e-22 4PXO-A nrPDB 94 6e-20 2YV9-A nrPDB 90 5e-19 3TOT-A nrPDB 90 8e-19 1AW9-A nrPDB 89 2e-18 6JWK-A nrPDB 88 3e-18 5F06-A nrPDB 85 2e-17 3IBH-A nrPDB 83 1e-16 4MK3-A nrPDB 81 4e-16 3VWX-A nrPDB 80 7e-16 3PR8-A nrPDB 79 2e-15 3R2Q-A nrPDB 77 5e-15 4YH2-A nrPDB 77 5e-15 5EY6-A nrPDB 77 5e-15 4PNG-A nrPDB 77 6e-15 3UAR-A nrPDB 76 1e-14 6F05-A nrPDB 76 1e-14 5F07-A nrPDB 76 1e-14 5A5K-A nrPDB 76 1e-14 4RI7-A nrPDB 73 7e-14 3M3M-A nrPDB 72 2e-13 2PMT-A nrPDB 72 2e-13 1JLV-A nrPDB 72 2e-13 1V2A-A nrPDB 70 5e-13 1AXD-A nrPDB 70 5e-13 1F2E-A nrPDB 70 8e-13 2IL3-A nrPDB 69 1e-12 1PN9-A nrPDB 69 2e-12 3M8N-A nrPDB 69 2e-12 5NR1-A nrPDB 69 2e-12 2GDR-A nrPDB 68 2e-12 3MAK-A nrPDB 67 7e-12 3GH6-A nrPDB 66 1e-11 5ZWP-A nrPDB 66 1e-11 1YQ1-A nrPDB 66 1e-11 4MPF-A nrPDB 65 3e-11 5F05-A nrPDB 64 4e-11 3C8E-A nrPDB 63 1e-10 5F0G-A nrPDB 63 1e-10 3GX0-A nrPDB 62 1e-10 4Q5F-A nrPDB 60 7e-10 1U3I-A nrPDB 60 7e-10 3LSZ-A nrPDB 60 9e-10 1N2A-A nrPDB 59 1e-09 4MDC-A nrPDB 58 3e-09 1B48-A nrPDB 58 4e-09 2CA8-A nrPDB 58 4e-09 4FQU-A nrPDB 56 9e-09 3M1G-A nrPDB 56 1e-08 2C3Q-A nrPDB 56 1e-08 1GUL-A nrPDB 56 1e-08 1VF1-A nrPDB 55 2e-08 6GZF-A nrPDB 55 2e-08 2GLR-A nrPDB 55 2e-08 3BBY-A nrPDB 55 2e-08 1G6W-A nrPDB 55 2e-08 4IKH-A nrPDB 55 3e-08 2VCV-A nrPDB 55 3e-08 2PVQ-A nrPDB 54 4e-08 4PTS-A nrPDB 52 1e-07 1F3B-A nrPDB 52 1e-07 3I6A-A nrPDB 51 3e-07 4G0L-A nrPDB 51 3e-07 3PPU-A nrPDB 51 4e-07 18GS-A nrPDB 50 6e-07 1PL2-A nrPDB 50 8e-07 2VCT-A nrPDB 50 9e-07 4LMW-A nrPDB 50 1e-06 2HNL-A nrPDB 49 1e-06 1EV4-A nrPDB 48 3e-06 1ZL9-A nrPDB 48 3e-06 5Y9Z-A nrPDB 47 5e-06 5LCZ-A nrPDB 47 5e-06 3KXO-A nrPDB 47 8e-06 2AAW-A nrPDB 47 9e-06 2WDU-A nrPDB 46 1e-05 1G7O-A nrPDB 46 1e-05 4Q5R-A nrPDB 46 1e-05 6GCB-A nrPDB 45 2e-05 1GSQ-A nrPDB 45 3e-05 2X8H-A nrPDB 43 1e-04 3IR4-A nrPDB 43 1e-04 5LKB-A nrPDB 43 1e-04 4LA1-A nrPDB 42 1e-04 1M0U-A nrPDB 42 2e-04 4USS-A nrPDB 42 2e-04 5AN1-A nrPDB 42 3e-04 4LMV-A nrPDB 41 3e-04 5F8B-A nrPDB 40 5e-04 2PBJ-A nrPDB 40 6e-04 5FWG-A nrPDB 40 0.001 6GC9-A nrPDB 39 0.001 1B4P-A nrPDB 38 0.003 1HNA-A nrPDB 38 0.004 3GRX-A nrPDB 38 0.004 1TU7-A nrPDB 37 0.007 4BVY-B nrPDB 36 0.013 2DC5-A nrPDB 36 0.013 2KLX-A nrPDB 36 0.016 3QMX-A nrPDB 35 0.036 1NM3-A nrPDB 34 0.043 4GTU-A nrPDB 34 0.057 1XWK-A nrPDB 33 0.064 1FHE-A nrPDB 33 0.12 1Z7R-A nrPDB 33 0.12 6JR6-A nrPDB 32 0.14 3IC4-A nrPDB 32 0.14 5CAX-A nrPDB 32 0.23 2MZC-A nrPDB 32 0.27 5W1J-A nrPDB 32 0.29 2WRT-A nrPDB 32 0.29 2X75-A nrPDB 31 0.36 3A58-B nrPDB 30 0.74 3H4X-A nrPDB 30 0.87 5Y4U-A nrPDB 30 0.90 3UIW-A nrPDB 29 1.4 3C1S-A nrPDB 29 1.7 2JAD-A nrPDB 28 3.4 3DAD-A nrPDB 28 3.4 3CG1-A nrPDB 28 3.5 2ATX-A nrPDB 28 3.5 5DXT-A nrPDB 28 3.6 4TR1-A nrPDB 28 3.8 1H75-A nrPDB 27 4.7 3AII-A nrPDB 27 5.2 3RE1-A nrPDB 27 5.3 >5LOL-A nrPDB Length = 215 Score = 298 bits (762), Expect = 2e-81, Method: Composition-based stats. Identities = 213/213 (100%), Positives = 213/213 (100%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV Sbjct: 3 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 62 Query: 61 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 120 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE Sbjct: 63 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 122 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV Sbjct: 123 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 182 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA Sbjct: 183 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA 215 >5ELG-A nrPDB Length = 221 Score = 296 bits (757), Expect = 6e-81, Method: Composition-based stats. Identities = 161/212 (75%), Positives = 184/212 (86%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MAL+ICVK AVGAPD LGDCPFSQR LLTLEEK L YK HLIN+SDKPQWFLDISP+GKV Sbjct: 1 MALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKV 60 Query: 61 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 120 PV+K+D KWV DSDVIVG+LEEKYP+P LKTP EFASVGS IFG F TFLKSKD+NDGSE Sbjct: 61 PVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSE 120 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 AL+ ELEALENHLK+H GPF+AGE+++AVDLSLAPKLYHL+VALGH+K+WSVPES V Sbjct: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 NY K LFS +SFE TK +++ V++GW KVN Sbjct: 181 HNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 >5IQY-A nrPDB Length = 216 Score = 291 bits (745), Expect = 1e-79, Method: Composition-based stats. Identities = 145/214 (67%), Positives = 179/214 (83%), Gaps = 2/214 (0%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MA+++CVK AVGAPD+LGDCPFSQRVLLTLEEKK+ Y+ L+++S+KP+WFL ISPEGKV Sbjct: 4 MAVEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKV 63 Query: 61 PVVKL-DGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGS 119 PV DGKW+ADSDVI ++EEK+P PSL TPPE+ASVGSKIF +FV FLKSKDA+DGS Sbjct: 64 PVFNSGDGKWIADSDVITQVIEEKFPTPSLVTPPEYASVGSKIFPSFVKFLKSKDASDGS 123 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 EKAL+DEL+AL+ HLK H GP+++GE ++A DLSL PKL+HL+VAL H+K W +PE+LTS Sbjct: 124 EKALLDELQALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTS 182 Query: 180 VRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 V Y KALFSRESF TK + ++AGW KVNA Sbjct: 183 VHAYTKALFSRESFVKTKPANQYLIAGWAPKVNA 216 >5D9W-A nrPDB Length = 230 Score = 288 bits (737), Expect = 1e-78, Method: Composition-based stats. Identities = 148/214 (69%), Positives = 171/214 (79%), Gaps = 2/214 (0%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 M +++CVK AVG PD LGD PFSQRVLLTLEEKK+PY+ LI+V +KP WFL ISPEGKV Sbjct: 18 MGVEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKV 77 Query: 61 PVVK-LDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGS 119 PV DGKW+ DSDVI ++EEKYP PSL TPPE+ASVGSKIF F TFLKSKD NDGS Sbjct: 78 PVFNGGDGKWIPDSDVITQVIEEKYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDPNDGS 137 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 EKAL+ EL+ALE HLK H GPF+ G+ I+A DLSLAPKLYHL+VAL H+K W +PE LT+ Sbjct: 138 EKALLTELQALEEHLKAH-GPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTN 196 Query: 180 VRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 V Y +ALFSRESF TKA KE ++AGW KVNA Sbjct: 197 VHAYTEALFSRESFIKTKAAKEHLIAGWAPKVNA 230 >5N9U-A nrPDB Length = 218 Score = 286 bits (731), Expect = 6e-78, Method: Composition-based stats. Identities = 165/213 (77%), Positives = 191/213 (89%), Gaps = 1/213 (0%) Query: 1 MALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV 60 MAL+ICVK AVGAP++LGDCPF QRVLL+LEEKK+PYK+HLIN+ DKPQWFL+ISPEGKV Sbjct: 1 MALEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKV 60 Query: 61 PVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE 120 PVVK+D KWVADSDVIVG+LEEK PEP L TPPEFASVGSKIF +FV FLKSKD NDG+E Sbjct: 61 PVVKIDDKWVADSDVIVGILEEKNPEPPLATPPEFASVGSKIFPSFVKFLKSKDPNDGTE 120 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 +AL++EL+AL+ HLK H GPF+AGEKITAVDLSLAPKLYHLEVALGH+KNW +P++LT V Sbjct: 121 QALLEELKALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHV 179 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 NY K LFSRESF+ T+A +E V+AGWE KVNA Sbjct: 180 LNYIKLLFSRESFKKTRAAEEHVIAGWEPKVNA 212 >5Y7I-A nrPDB Length = 261 Score = 215 bits (548), Expect = 1e-56, Method: Composition-based stats. Identities = 60/232 (25%), Positives = 104/232 (44%), Gaps = 23/232 (9%) Query: 2 ALDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVP 61 ++++ +K +V G+CPF QR+ + L K + + +++ KP D++P P Sbjct: 29 SIELFIKAGHDGENV-GNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAPGTNPP 87 Query: 62 VVKLDGKWVADSDVIVGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAN 116 + +G D I LE+ +YP S F VG+ IF F F+K+ N Sbjct: 88 FLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESF-DVGADIFAKFSAFIKNSPNN 146 Query: 117 DGSEKALVDELEALENHLKT----------------HSGPFVAGEKITAVDLSLAPKLYH 160 EK L+ E + L+++L + + F+ G+++T D +L PKL+ Sbjct: 147 PLQEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHV 206 Query: 161 LEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 + VA Y N+ +P+ T V Y K R+ F+ T + + S N Sbjct: 207 IRVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVAN 258 >2R5G-A nrPDB Length = 247 Score = 207 bits (527), Expect = 3e-54, Method: Composition-based stats. Identities = 58/233 (24%), Positives = 110/233 (47%), Gaps = 25/233 (10%) Query: 3 LDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV 62 +++ VK + +G+CPF QR+ + L K + + ++++ KP+ D++P P Sbjct: 14 IELFVKAGSDG-ESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPF 72 Query: 63 VKLDGKWVADSDVIVGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKS--KDA 115 + + + D I LE+ +YP S K F VG +F F ++K+ K+A Sbjct: 73 LVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESF-DVGCNLFAKFSAYIKNTQKEA 131 Query: 116 NDGSEKALVDELEALENHLKT----------------HSGPFVAGEKITAVDLSLAPKLY 159 N EK+L+ E + L+++L T F+ G+++T D SL PKL Sbjct: 132 NKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLN 191 Query: 160 HLEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 ++VA Y+++ +P + V Y ++RE F +T + + + + + Sbjct: 192 IIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAK 244 >4K0G-A nrPDB Length = 251 Score = 206 bits (524), Expect = 6e-54, Method: Composition-based stats. Identities = 56/234 (23%), Positives = 106/234 (45%), Gaps = 25/234 (10%) Query: 3 LDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV 62 +++ VK + G+ PFSQR+ + L K + + ++ + + + P G++P Sbjct: 18 VELFVKAGSDGAKI-GNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 76 Query: 63 VKLDGKWVADSDVIVGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDA-- 115 + + D++ I LE +YP+ + P E + G IF F ++K+ + Sbjct: 77 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPAL 135 Query: 116 NDGSEKALVDELEALENHLKT----------------HSGPFVAGEKITAVDLSLAPKLY 159 ND EK L+ L+ L+N+L + F+ G ++T D +L PKL+ Sbjct: 136 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 195 Query: 160 HLEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 213 ++V Y+ +++PE+ V Y ++RE F +T E + +E A Sbjct: 196 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 249 >2D2Z-A nrPDB Length = 261 Score = 206 bits (523), Expect = 9e-54, Method: Composition-based stats. Identities = 59/233 (25%), Positives = 109/233 (46%), Gaps = 25/233 (10%) Query: 3 LDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV 62 +++ VK + +G+CPFSQR+ + L K + + +++ KP +++P P Sbjct: 19 IELFVKAGSDG-ESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 Query: 63 VKLDGKWVADSDVIVGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKS--KDA 115 + + + D + I LEE KY + S K P E + G IF F ++K+ +A Sbjct: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEA 136 Query: 116 NDGSEKALVDELEALENHL----------------KTHSGPFVAGEKITAVDLSLAPKLY 159 N+ E+ L+ L+ L+ +L K + F+ G ++T D +L PKL+ Sbjct: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLH 196 Query: 160 HLEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 ++V Y+N+ +P+ +T + Y +SR+ F NT + V + Sbjct: 197 IVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAK 249 >2VO4-A nrPDB Length = 219 Score = 197 bits (502), Expect = 2e-51, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 83/199 (41%), Gaps = 15/199 (7%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVG 78 PF RV + L EK + Y+ ++ +K L ++P K+PV+ +GK + +S + V Sbjct: 13 SPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICESLIAVQ 72 Query: 79 LLEEKYPEP-SLKTPPEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDEL 127 +EE + + L + ++ + +V + + + ++K ++ L Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAKKEFIEAL 132 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 + LE L + + G+ + VD++L P Y A + ++ +AK Sbjct: 133 KLLEEQLGDKT--YFGGDNLGFVDIALVP-FYTWFKAYETFGTLNIESECPKFIAWAKRC 189 Query: 188 FSRESFENTKAKKEIVVAG 206 +ES + ++ V Sbjct: 190 LQKESVAKSLPDQQKVYEF 208 >5J5N-A nrPDB Length = 231 Score = 196 bits (498), Expect = 6e-51, Method: Composition-based stats. Identities = 47/196 (23%), Positives = 85/196 (43%), Gaps = 15/196 (7%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGK-VPVVKLDGKWVADSDVIVG 78 PF RV L L EK + Y+ ++ +K L ++P K +PV+ +GK V +S +IV Sbjct: 25 SPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQ 84 Query: 79 LLEEKYPEPSLKTP-PEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDEL 127 ++E + + + P + S+ + FV + K + + ++K +D L Sbjct: 85 YIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDSL 144 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 + +E L P+ GE I VD++L P Y A N+++ + Y K Sbjct: 145 KLMEGELGDK--PYFGGETIGYVDIALVP-FYSWFYAYETIGNFNIEAECPKMIAYCKRC 201 Query: 188 FSRESFENTKAKKEIV 203 +E+ + V Sbjct: 202 LQKETVSKALEDPQKV 217 >4CHS-A nrPDB Length = 219 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 83/199 (41%), Gaps = 15/199 (7%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVG 78 PF RV + L EK + Y+ ++ +K L ++P K+PV+ +GK +++S + V Sbjct: 13 SPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISESLIAVQ 72 Query: 79 LLEEKYPEP-SLKTPPEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDEL 127 +EE + + L + ++ + +V + + + ++K ++ L Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEKEAAKKEFIEAL 132 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 + LE L + + G+ I VD++L P Y + + ++ +AK Sbjct: 133 KLLEEQLGDKT--YFGGDNIGFVDIALVP-FYTWFKVYETFGSLNIENECPRFVAWAKRC 189 Query: 188 FSRESFENTKAKKEIVVAG 206 +ES + + V Sbjct: 190 LQKESVAKSLPDQHKVYEF 208 >5ECL-B nrPDB Length = 223 Score = 188 bits (478), Expect = 1e-48, Method: Composition-based stats. Identities = 44/196 (22%), Positives = 85/196 (43%), Gaps = 15/196 (7%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGLL 80 F R + L EK + ++ + S+K L +P K+PV+ +GK V +S +V + Sbjct: 21 FGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLVHNGKPVCESLNVVQYV 80 Query: 81 EEKYPEPSLKTP-PEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDELEA 129 +E +PE + P + ++ + FV + K + + +K ++ ++ Sbjct: 81 DEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKGEEQEAGKKEFIEAVKI 140 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 LE+ L P+ G+ VD+SL + A + N+S+ + +AK Sbjct: 141 LESELGDK--PYFGGDSFGYVDISLITFSSWFQ-AYEKFGNFSIESESPKLIAWAKRCME 197 Query: 190 RESFENTKAKKEIVVA 205 +ES + E +VA Sbjct: 198 KESVSKSLPDSEKIVA 213 >3FY7-A nrPDB Length = 250 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 50/227 (22%), Positives = 98/227 (43%), Gaps = 23/227 (10%) Query: 3 LDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV 62 L + VK + + +G CP QR+ + L K +P+ ++ P D +P ++P+ Sbjct: 26 LQLFVKASEDG-ESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPI 84 Query: 63 VKLDGKWVADSDVIVGLLEEK-----YPEPSLKTPPEFASVGSKIFGAFVTFLKSKDA-- 115 + D D+ I LEE +P + + E + G+ +F F F+K+ Sbjct: 85 LLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRY-RESNTAGNDVFHKFSAFIKNPVPAQ 143 Query: 116 NDGSEKALVDELEALENHLKT--------------HSGPFVAGEKITAVDLSLAPKLYHL 161 ++ + L+ L L+++L+ F+ G+++T D SL PKL+ + Sbjct: 144 DEALYQQLLRALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIV 203 Query: 162 EVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWE 208 + H++ +P L VR Y + + F+ T ++A + Sbjct: 204 DTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAYR 250 >5G5A-A nrPDB Length = 221 Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 84/197 (42%), Gaps = 15/197 (7%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGLL 80 F R + LEEK + + ++ +K L+++P K+PV+ +G V +S + + + Sbjct: 15 FGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVLIHNGNPVCESLIQIEYI 74 Query: 81 EEKYP-EPSLKTPPEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDELEA 129 +E +P + L + +K +G F+ + + ++ +K ++ L+ Sbjct: 75 DEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEEHEAGKKEFIEILKT 134 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 LE+ L + + GE VD++L Y A + ++S+ + + K Sbjct: 135 LESELGDKT--YFGGETFGYVDIALI-GFYSWFEAYEKFGSFSIEAECPKLIAWGKRCVE 191 Query: 190 RESFENTKAKKEIVVAG 206 RES + E ++ Sbjct: 192 RESVAKSLPDSEKIIKF 208 >3QAG-A nrPDB Length = 239 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 40/180 (22%), Positives = 73/180 (40%), Gaps = 16/180 (8%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 78 CP+S R L L+ K + ++ IN+ +KP+W+ P G +PV++ + + +S + Sbjct: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESVIACE 91 Query: 79 LLEEKYPEPSLKTPPEFASVG-----------SKIFGAFVTFLKSKDANDGSEKALVDEL 127 L++ YP L + + + L+S + + AL E Sbjct: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRESTNLKAALRQEF 151 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 LE L+ + F G I+ +D L P L+V Y ++R + A+ Sbjct: 152 SNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDV----YGILDCVSHTPALRLWISAM 207 >4PQI-A nrPDB Length = 241 Score = 167 bits (423), Expect = 3e-42, Method: Composition-based stats. Identities = 50/207 (24%), Positives = 89/207 (42%), Gaps = 17/207 (8%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINV--SDKPQWFL-DISPEGKVPVVKLDGKWVADSDV 75 CPF+QRV +T K L + L+ + ++P W+ + P KVP ++ +GK +S Sbjct: 40 TCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLD 99 Query: 76 IVGLLEEKYPEPSLKTPP--------EFASVGSKIFGAFVTFLKSKDANDGSEKALVDEL 127 ++ LE + PSL E S K G T K A + Sbjct: 100 LIKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAKEAGP-----AF 154 Query: 128 EALENHL-KTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKA 186 + LEN L K GPF G++ + VD++ P + L + L + + + + + Sbjct: 155 DHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEE 214 Query: 187 LFSRESFENTKAKKEIVVAGWESKVNA 213 + E+++ TK + +V ++ + A Sbjct: 215 VNKIEAYKQTKTDPKELVEFYKKRFLA 241 >4QQ7-A nrPDB Length = 207 Score = 167 bits (422), Expect = 5e-42, Method: Composition-based stats. Identities = 45/199 (22%), Positives = 96/199 (48%), Gaps = 19/199 (9%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVG 78 CPFSQR L L EK + ++ +++ +KP+ ++P G+VP++ + +S++I Sbjct: 13 TCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINE 72 Query: 79 LLEEKYPEPSLKTPPEFASVGSKIF--------GAFVTFLKSKDANDGSEKALVDELEAL 130 ++E++P P L +++F V+ L++ + +EK A+ Sbjct: 73 YIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLEN-EKGKAAEKNHEKARLAI 131 Query: 131 ENHLKTHSG-----PFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAK 185 + L + ++ GE+ + +D+++AP L+ L+ HY + ++ + YA+ Sbjct: 132 RDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLD----HY-GIELSKNAAPLMKYAE 186 Query: 186 ALFSRESFENTKAKKEIVV 204 +FSR ++ E V+ Sbjct: 187 RIFSRPAYIEALTPSEKVM 205 >6EP7-A nrPDB Length = 220 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 83/195 (42%), Gaps = 15/195 (7%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVGLL 80 + R + LEEKK+ Y+ ++S+K L ++P K+PV+ +GK + +S + V + Sbjct: 15 YGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVLIHEGKPICESIIQVQYI 74 Query: 81 EEKYPEPSLKTP-PEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVDELEA 129 +E +P+ + P + ++ + ++ + +S + + ++ ++ L+ Sbjct: 75 DELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKALWSESGEKQEAAKIEFIEVLKT 134 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 L++ L + G + VD++ Y N S+ + +A+ Sbjct: 135 LDSELGDKY--YFGGNEFGLVDIAFI-GFYSWFRTYEEVANLSIVLEFPKLMAWAQRCLK 191 Query: 190 RESFENTKAKKEIVV 204 RES + V+ Sbjct: 192 RESVAKALPDSDKVL 206 >2CZ2-A nrPDB Length = 223 Score = 164 bits (414), Expect = 3e-41, Method: Composition-based stats. Identities = 42/200 (21%), Positives = 85/200 (42%), Gaps = 30/200 (15%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEGKVPVVKLDGKWVADSDVIV 77 S RV + L K + Y+ IN+ + F ++P +VP +K+DG + S I+ Sbjct: 24 SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIM 83 Query: 78 GLLEEKYPEPSLKTPPEFASV----GSKIFGAFVTFLKS---------KDANDGSEKALV 124 LEE P P L S + + + L++ ++ ++K + Sbjct: 84 EYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVIT 143 Query: 125 DELEALENHLKTHSGPFVAGEKITAVDLSLAPKL---YHLEVALGHYKNWSVPESLTSVR 181 ALE L++ +G + G++++ D+ L P++ +V L Y ++ Sbjct: 144 SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY---------PTIS 194 Query: 182 NYAKALFSRESFENTKAKKE 201 + K L + E F+ + +++ Sbjct: 195 HINKELLALEVFQVSHPRRQ 214 >4J2F-A nrPDB Length = 223 Score = 161 bits (407), Expect = 2e-40, Method: Composition-based stats. Identities = 40/204 (19%), Positives = 84/204 (41%), Gaps = 14/204 (6%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVG 78 PFS RV+ L+ K +PY+ ++ +K L +P K+PV+ GK + +S +I+ Sbjct: 13 SPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILE 72 Query: 79 LLEEKYPEPSLKTPPEFASVGSKIFGAFV------TFLKSKDANDGSEKALVDELEAL-- 130 L+E +PE L ++ + F+ + + + EKA+ + LE L Sbjct: 73 YLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEELEKAVKNCLEVLKT 132 Query: 131 --ENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV--PESLTSVRNYAKA 186 E+ + + G+KI VD++ + H + V + + + + Sbjct: 133 IEEHAMGVSDDKYFGGDKIGIVDIAFC-GIAHWLGVIEEVAGVKVLESQKFPRLHAWTEN 191 Query: 187 LFSRESFENTKAKKEIVVAGWESK 210 + ++ + A ++ + Sbjct: 192 FKEAPIIKENLPDRDQMTAFFKRR 215 >3LFL-A nrPDB Length = 240 Score = 160 bits (404), Expect = 5e-40, Method: Composition-based stats. Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 16/193 (8%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVK-LDGKWVADSDVIVG 78 CPF++R L L+ K + ++ IN+ +KP+WF +P G VPV++ G+ + +S + Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 79 LLEEKYPEPSLKTPPEFASV--------GSKIFGAFVTFLKSKDAND--GSEKALVDELE 128 L+E YP L + SK+ +F++S++ D G ++ E Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFT 151 Query: 129 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 LE L F G I+ +D + P LE + + ++ + A+ Sbjct: 152 KLE-VLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN----ECVDHTPKLKLWMAAMK 206 Query: 189 SRESFENTKAKKE 201 + ++ Sbjct: 207 EDPTVSALLTSEK 219 >1FW1-A nrPDB Length = 216 Score = 156 bits (395), Expect = 5e-39, Method: Composition-based stats. Identities = 47/200 (23%), Positives = 84/200 (42%), Gaps = 30/200 (15%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDK-----PQWFLDISPEGKVPVVKLDGKWVADSDVIV 77 S RV + L K + YKT IN+ + F ++P +VP +K+DG + S I+ Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 78 GLLEEKYPEPSLKTPPEFASVG----SKIFGAFVTFLKS----KDAND-----GSEKALV 124 LEE P P L S + + L++ K + ++ A+ Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAIT 136 Query: 125 DELEALENHLKTHSGPFVAGEKITAVDLSLAPKL---YHLEVALGHYKNWSVPESLTSVR 181 ALE L++ +G + G+++T DL L P++ +V L Y ++ Sbjct: 137 CGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPY---------PTIS 187 Query: 182 NYAKALFSRESFENTKAKKE 201 + K L E+F+ + ++ Sbjct: 188 SINKRLLVLEAFQVSHPCRQ 207 >3WD6-A nrPDB Length = 256 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 46/199 (23%), Positives = 77/199 (38%), Gaps = 10/199 (5%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 78 CP++QR +L L K++ Y+ I++ DKP+W S KVP +++ + + +S V V Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAIEIAEDVTIYESLVTVE 97 Query: 79 LLEEKYPEPSLKTPPEFASVGSKIFGA--------FVTFLKSKDA-NDGSEKALVDELEA 129 L+E YP+ L KI F+ LK D N+ A L+ Sbjct: 98 YLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQSLFIKILKFSDTVNEEHVAAYHKALDF 157 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 ++ LK F+ G + D + P L + P + + Y + Sbjct: 158 IQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDERVRLEPSKYSLLLEYIDNMLK 217 Query: 190 RESFENTKAKKEIVVAGWE 208 + EI+ E Sbjct: 218 DSAVSQYLIPLEILAKFHE 236 >2YV7-A nrPDB Length = 260 Score = 154 bits (389), Expect = 2e-38, Method: Composition-based stats. Identities = 39/212 (18%), Positives = 89/212 (41%), Gaps = 8/212 (3%) Query: 3 LDICVKVAVGAPDVLGDCPFSQRVLLTL----EEKKLPYKTHLINVSDKPQWFLDISPEG 58 +++ +K + G C F Q + L E K + K +++ P F Sbjct: 23 IELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEAT 82 Query: 59 KVPVVKLDGKWVADSDVIVGLLEEKYPEP--SLKTPPEFASVGSKIFGAFVTFLKSKDAN 116 P++ +G + +++ I + + P E A++ ++ L KD Sbjct: 83 HPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIENLYVKLKLMLVKKD-- 140 Query: 117 DGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPES 176 + AL+ L + +HL + F+ G+ + D L P+L H+ VA ++ ++ +P Sbjct: 141 EAKNNALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTH 200 Query: 177 LTSVRNYAKALFSRESFENTKAKKEIVVAGWE 208 LT++ Y ++ ++F + + ++ ++ Sbjct: 201 LTALWRYMYHMYQLDAFTQSCPADQDIINHYK 232 >4IGJ-A nrPDB Length = 242 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 29/202 (14%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKL--DGK--WVADSDV 75 + RV L L K L Y+ +++ + Q+ +P +VPV+++ DG+ + S Sbjct: 36 AWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMA 95 Query: 76 IVGLLEEKYPEPSLKTPPEFASVGSKIFGAFV-------------TFLKSKDANDGSEKA 122 I+ LEE++PEP+L P + + V L+ K E A Sbjct: 96 ILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPGWDREWA 155 Query: 123 ---LVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 + L ALE ++ +G F G+ T D L P+LY+ + + + Sbjct: 156 RFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLDLEPY------PT 209 Query: 180 VRNYAKALFSRESFENTKAKKE 201 +R +A + F+ ++ Sbjct: 210 LRRVDEACAALAPFQAAHPDRQ 231 >4AGS-A nrPDB Length = 471 Score = 148 bits (373), Expect = 2e-36, Method: Composition-based stats. Identities = 49/212 (23%), Positives = 87/212 (41%), Gaps = 18/212 (8%) Query: 16 VLGDCPFSQRVLLTLEEKKLPYKTHLINVSDK-PQWFLDISPEGKVPVVKL---DGKWVA 71 V CPF RV + EK++ Y + + ++ PQW+ I+P VP +++ D +++ Sbjct: 31 VSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADKRFMF 90 Query: 72 DSDVIVGLLEEK-YPEPSL-------KTPPEFASVGS-KIFGAFVTFLKSKDANDGSEKA 122 +S +I L+ P +L + EF GA L+ D G ++ Sbjct: 91 ESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLLR--DPLSGEKRK 148 Query: 123 LVDELEALENHL---KTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 +D+ A + L +GP+ + T D++L P L L+ AL +Y + V Sbjct: 149 AMDDNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDVFCKAPR 208 Query: 180 VRNYAKALFSRESFENTKAKKEIVVAGWESKV 211 ++ A R S T + + V Sbjct: 209 MKALWAAAAQRASVRETSPTAAQCIENYRHLV 240 Score = 93.9 bits (232), Expect = 4e-20, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 70/189 (37%), Gaps = 13/189 (6%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 78 CPF R L E +K + + +P+W+ I+P VP + G+ V +S +IV Sbjct: 261 CPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQ 320 Query: 79 LLEEKYPEPSLKTP--PEFASVGSKIFGAFVTFLKSK------DANDGSEKALVDELEAL 130 ++ + S P F + + ++ L L Sbjct: 321 YIDCVATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQWAAGEL 380 Query: 131 ENHLKTH---SGPFVAGEKITAVDLSLAPKLYHLEVALGHY-KNWSVPESLTSVRNYAKA 186 E L H GPF G+++ A D+++ P L + + + + + + A+A Sbjct: 381 EQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGYDLFAHFPLLNGLAEA 440 Query: 187 LFSRESFEN 195 + ++ Sbjct: 441 GMATPEAKS 449 >3RBT-A nrPDB Length = 246 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 38/205 (18%), Positives = 80/205 (39%), Gaps = 13/205 (6%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL----DGKWVADSDVI 76 P+ RVLL LE K++ Y+ + ++ P+WF +P K+PV+++ +++ +S VI Sbjct: 36 PYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLFESVVI 95 Query: 77 VGLLEEKYPEPSLKTPPEFASVGSKI----FGAFVT-FLKSKDANDG-SEKALVDELEAL 130 L+EKY +L + + ++ F + L+ D N + ++ LE Sbjct: 96 CDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLECFDTNFAFGSEQIIQTLEIF 155 Query: 131 ENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVA-LGHYKNW-SVPESLTSVRNYAKALF 188 E L + G + +D + P + L + + + + + ++ Sbjct: 156 EKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLRCVNDRKFVEKKSLFPNFADWGDQ-M 214 Query: 189 SRESFENTKAKKEIVVAGWESKVNA 213 + A + A Sbjct: 215 QLDDIVKKHAHSPQEYFDYYKNARA 239 >1E6B-A nrPDB Length = 221 Score = 142 bits (359), Expect = 9e-35, Method: Composition-based stats. Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 33/203 (16%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADSDVIVGL 79 + RV + L K L Y+ +N+ Q+ F I+P G VP + + DS I+ Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMY 79 Query: 80 LEEKYPEPSLKTPP------EFASVGSKIFG-------AFVTFLKSK----DANDGSEKA 122 L+EKYPEP L + ++ + G A + +++ K + A Sbjct: 80 LDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAWVNNA 139 Query: 123 LVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLY----HLEVALGHYKNWSVPESLT 178 + ALE L +G G++I DL LAP+++ ++ + Y Sbjct: 140 ITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQINMEPY---------P 190 Query: 179 SVRNYAKALFSRESFENTKAKKE 201 ++ ++ +F+N +K+ Sbjct: 191 TLAKCYESYNELPAFQNALPEKQ 213 >1OYJ-A nrPDB Length = 231 Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 76/204 (37%), Gaps = 21/204 (10%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVG 78 PF QR + + EK L ++ ++ +K L +P K+PV+ G+ V++S VI+ Sbjct: 15 SPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLHAGRPVSESLVILQ 74 Query: 79 LLEEKYPE-PSLKTPPEFAS----------------VGSKIFGAFVTFLK-SKDANDGSE 120 L++ +P P L P V K++ + + + Sbjct: 75 YLDDAFPGTPHLLPPANSGDADAAYARATARFWADYVDRKLYDCGSRLWRLKGEPQAAAG 134 Query: 121 KALVDELEALENHLKTH-SGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 + + + L LE L G ++ VD++L P + +SV E Sbjct: 135 REMAEILRTLEAELGDREFFGGGGGGRLGFVDVALVPFTA-WFYSYERCGGFSVEEVAPR 193 Query: 180 VRNYAKALFSRESFENTKAKKEIV 203 + +A+ +S E V Sbjct: 194 LAAWARRCGRIDSVVKHLPSPEKV 217 >3UBL-A nrPDB Length = 242 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 18/176 (10%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 + +V L + EK L Y+ I S + + FL ISP GK+PV+++DGK++ +S I+ L+ Sbjct: 14 YVNKVKLGILEKGLEYEQIRIAPSQE-EDFLKISPMGKIPVLEMDGKFIFESGAILEFLD 72 Query: 82 EKYPEPSLKTP--PEFASVGSKIFGAFVTFLK-------------SKDANDGSEKALVDE 126 +P+ P P A+ +I T+L S + + LV Sbjct: 73 TIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEIVEEVHSTLVKG 132 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRN 182 ++AL+ ++ P++AG T D S L L+ L + + P L + Sbjct: 133 IKALQRVVRFS--PYIAGNVFTLADCSGFAHLSVLDEELRPFYPNNHPLDLLNGWK 186 >1GWC-A nrPDB Length = 230 Score = 115 bits (288), Expect = 1e-26, Method: Composition-based stats. Identities = 42/205 (20%), Positives = 83/205 (40%), Gaps = 19/205 (9%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISP-EGKVPVVKLDGKWVADSDVIVG 78 PF RV L L K L Y+ ++ K + L +P K+PV+ +G V +S +I+ Sbjct: 15 SPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVLIHNGAPVCESMIILQ 74 Query: 79 LLEEKY--PEPSLKTPPEFASVGSKIFGAFV---------TFLKSK--DANDGSEKALVD 125 ++E + PSL + ++ + A+V +L+ K + +K Sbjct: 75 YIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEEEKSEGKKQAFA 134 Query: 126 ELEALENHLK--THSGPFVAGEKITAVDLSLAPKLYHLEV--ALGHYKNWSVPESLTSVR 181 + LE L+ + G F G+ + VD++L L ++V AL K + + Sbjct: 135 AVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEALSGDKIFD-AAKTPLLA 193 Query: 182 NYAKALFSRESFENTKAKKEIVVAG 206 + + ++ + ++ Sbjct: 194 AWVERFIELDAAKAALPDVGRLLEF 218 >2JL4-A nrPDB Length = 213 Score = 105 bits (263), Expect = 1e-23, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 73/206 (35%), Gaps = 36/206 (17%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADSDVIVGL 79 S R+ + L K +PY+ +++ + F ++P+ VP + + + S I+ Sbjct: 13 SHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQVLIQSPAIIEW 72 Query: 80 LEEKYPEPSLKTPPEFASVGSKIFGAFV----------TFLKSKDANDGSEKALVD---- 125 LEE+YP P+L + A V L+ G+++A ++ Sbjct: 73 LEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKTFGADEAAINAWCG 132 Query: 126 -----ELEALENHLKT--HSGPFVAGEKITAVDLSLAPKLY---HLEVALGHYKNWSVPE 175 +A E L G + G+ T D L P++ +V L Y Sbjct: 133 TWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARRFQVDLTPY------- 185 Query: 176 SLTSVRNYAKALFSRESFENTKAKKE 201 +R A ++F + Sbjct: 186 --PLIRAVDAACGELDAFRRAAPAAQ 209 >3NIV-A nrPDB Length = 222 Score = 104 bits (259), Expect = 4e-23, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 73/203 (35%), Gaps = 32/203 (15%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDK-----PQWFLDISPEGKVPVVKLDGKWVADSDVIV 77 RV + L KK+ Y+ +++ + + I+P+ VP + ++G+ ++ S I+ Sbjct: 14 CYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQILSQSMAII 73 Query: 78 GLLEEKYPEPSLKTPPEFASVGSKIFGAFVTF-------------LKSK------DANDG 118 LEE +PE L F K V LK + + Sbjct: 74 DYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQFNANEEQVLEW 133 Query: 119 SEKALVDELEALENHLKT--HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPES 176 L +A E L P G ++ D+ L P++Y+ H ++ + S Sbjct: 134 YHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYN-----AHRFHFDM-AS 187 Query: 177 LTSVRNYAKALFSRESFENTKAK 199 + + + +F + + Sbjct: 188 YPIINEINEYCLTLPAFHDAAPE 210 >3LG6-A nrPDB Length = 235 Score = 99.7 bits (247), Expect = 8e-22, Method: Composition-based stats. Identities = 37/211 (17%), Positives = 71/211 (33%), Gaps = 39/211 (18%) Query: 25 RVLLTLEEKKLPYKTHLINVSDKPQ---WFLDISPEGKVPVVKLDGK-----------WV 70 R+ + K +PY H +N+ Q + ++P VP++ + + Sbjct: 23 RLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNTVSPSSASFSI 82 Query: 71 ADSDVIVGLLEEKYPE------PSLKTPPEFASVGS--KIFGAFVTFLKS---------- 112 S + LEE P P + P A V + I V + + Sbjct: 83 GQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQPVTNLKIQKKVKAL 142 Query: 113 -KDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNW 171 D S A+E L+ +G F G++IT D+ L P ++ E + Sbjct: 143 DGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAAERVGMDLARF 202 Query: 172 SVPESLTSVRNYAKALFSRESFENTKAKKEI 202 + + + + E+ + +K+ Sbjct: 203 PITK------RVFEEMLKEEAVQKAHWQKQE 227 >4PXO-A nrPDB Length = 238 Score = 93.5 bits (231), Expect = 6e-20, Method: Composition-based stats. Identities = 37/204 (18%), Positives = 71/204 (34%), Gaps = 35/204 (17%) Query: 25 RVLLTLEEKKLPYKTHLINVSDKPQ---WFLDISPEGKVPVV-KLDGKWVADSDVIVGLL 80 RV + L K + Y+ +++ Q FL I+P+G VP + DG + S I+ L Sbjct: 37 RVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALFDGDGPPLTQSLAILDYL 96 Query: 81 EEKYPEPSLK---------------------TPPEFASVGSKIFGAFVTFLKSKDANDGS 119 EE L P V + + + L + + Sbjct: 97 EETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMENYG--LPRERMLEFL 154 Query: 120 EKALVDELEALENHLKTHS--GPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESL 177 A + L+ LE L + G F G+ ++ DL L L+ + Sbjct: 155 RNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLI-SLW----VGTGIFGID-TAAY 208 Query: 178 TSVRNYAKALFSRESFENTKAKKE 201 +V+ ++ + + ++ ++ Sbjct: 209 PTVKRISEEVLALDAVARAHPLRQ 232 >2YV9-A nrPDB Length = 291 Score = 90.4 bits (223), Expect = 5e-19, Method: Composition-based stats. Identities = 39/236 (16%), Positives = 88/236 (37%), Gaps = 28/236 (11%) Query: 3 LDICVKVAVGAPDVLGDCPFSQRVLL---TLEEKKL-PYKTHLINVSDKPQWFLDISPEG 58 L++ VK + +G F Q + L E + + +NV + F Sbjct: 20 LELYVKASGIDARRIGADLFCQEFWMELYALYEIGVARVEVKTVNV--NSEAFKKNFLGA 77 Query: 59 KVPVVKLDGK--WVADSDVIVG---LLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSK 113 + P++ + K D+ I G L +++ P + P ++ F FL++K Sbjct: 78 QPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVPLFEKDPSAEKRIENLYRNFKLFLRAK 137 Query: 114 DANDGSEKA-----------------LVDELEALENHLKTHSGPFVAGEKITAVDLSLAP 156 D +K + ++L ++ L ++ G +T D L P Sbjct: 138 VEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMP 197 Query: 157 KLYHLEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 +L+H+ + + +P + T + Y + +F + + ++ ++ ++N Sbjct: 198 RLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPADQDIIHHYKEQMN 253 >3TOT-A nrPDB Length = 226 Score = 89.7 bits (221), Expect = 8e-19, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 78/201 (38%), Gaps = 20/201 (9%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 78 P++++V + L EKK+ Y+ L +V + +P GKVP + + DG + DS VI Sbjct: 11 SPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIAE 70 Query: 79 LLEEKYPEPSLKTPPEFASVGSKIFGAFVTFL-----------KSKDANDGSEKALVDEL 127 + P L P V + + A L + SE + + Sbjct: 71 YADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSESWITRQH 130 Query: 128 EALENHLKT-----HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRN 182 ++ LK + G +T D+++ L +L+ +W E ++ Sbjct: 131 HKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLD-FRQPQVDWR--EQHANLAA 187 Query: 183 YAKALFSRESFENTKAKKEIV 203 + + R SF T+ + E + Sbjct: 188 FYTRIEKRPSFLETQPQAENL 208 >1AW9-A nrPDB Length = 216 Score = 88.5 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 40/205 (19%), Positives = 77/205 (37%), Gaps = 31/205 (15%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVS---DKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 P RV L EK L ++ ++++ K FL ++P G++P + + + +S I Sbjct: 11 SPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAI 70 Query: 77 VGLLEEKY--------PEPSLKTPPE----------FASVGSKIFGAFVTFLKSKDANDG 118 + KY P + E + + +F V L + Sbjct: 71 NRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRPLLGGAPDAA 130 Query: 119 ----SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVP 174 + L L+ E HL ++AG++ T D + A L + L + Sbjct: 131 VVDKHAEQLAKVLDVYEAHL--ARNKYLAGDEFTLADANHASYL----LYLSKTPKAGLV 184 Query: 175 ESLTSVRNYAKALFSRESFENTKAK 199 + V+ + +A+ +R +F+ T A Sbjct: 185 AARPHVKAWWEAIVARPAFQKTVAA 209 >6JWK-A nrPDB Length = 222 Score = 88.1 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 67/206 (32%), Gaps = 36/206 (17%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQWFL---DISPEGKVPVVK-LDGKWVADSDVIVG 78 S RV + L K L Y+ +N+ Q +P G +P + DG+ + S I+ Sbjct: 12 SYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSLAIID 71 Query: 79 LLEEKYPEPSLKTPPEFASVGSKIFGAFVTF-------------------LKSKDANDGS 119 L+ PEP L + V + ++D Sbjct: 72 YLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVLGIDAEDRQRWY 131 Query: 120 EKALVDELEALENHLKTHSG-PFVAGEKITAVDLSLAPKLYHLE---VALGHYKNWSVPE 175 + + L A E L H F AG V+ L P+L + L Y Sbjct: 132 AHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCDLAPY------- 184 Query: 176 SLTSVRNYAKALFSRESFENTKAKKE 201 ++ + E+F+ +++ Sbjct: 185 --PALLELEGRCLALEAFQRASPERQ 208 >5F06-A nrPDB Length = 216 Score = 85.1 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 44/211 (20%), Positives = 81/211 (38%), Gaps = 37/211 (17%) Query: 12 GAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVS---DKPQWFLDISPEGKVPVVKLDGK 68 GAP + C + RVL L EK L ++ +++ K FL +P G++P ++ D Sbjct: 6 GAP--MSTC--TSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 69 WVADSDVIVGLLEEKYPEP---SLKTPPEFASVGSKIFGAF-----------------VT 108 + +S I + EK+ ++ + K++ V Sbjct: 62 TLFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMVA 121 Query: 109 FLKSKDAN----DGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVA 164 L+ + D + + L L+ E L S ++AG+ + DL P Y+L Sbjct: 122 PLRGNSPDQTIIDDNVEKLGKVLDIYEAKL--SSTKYLAGDFYSLADLHHLPYTYYL--- 176 Query: 165 LGHYKNWSVPESLTSVRNYAKALFSRESFEN 195 SV V+ + + + SR +F+ Sbjct: 177 -MKTPAASVVNERPHVKAWWEDISSRPAFKK 206 >3IBH-A nrPDB Length = 233 Score = 82.7 bits (203), Expect = 1e-16, Method: Composition-based stats. Identities = 44/204 (21%), Positives = 74/204 (36%), Gaps = 36/204 (17%) Query: 21 PFSQRVLLTLEEKKL--PYKTHLINVSD---KPQWFLDISPEGKVPVVKLD-GKWVADSD 74 P+ RV + L EK + + IN+ K FL + G VPV++LD G +A+ Sbjct: 28 PYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECT 87 Query: 75 VIVGLLEEKYPEPSL--KTPPEFA-------SVGSKIFGAFVTFLKSKDAN--------D 117 I ++ P+L KTP E ++ + Sbjct: 88 AITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQ 147 Query: 118 GSEKALVDELEAL------ENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNW 171 E L +AL + L+ P+VAG+ + D+++ L Sbjct: 148 NKEWGLRQRDKALHGMHYFDTVLRER--PYVAGDSFSMADITVIAGL-----IFAAIVKL 200 Query: 172 SVPESLTSVRNYAKALFSRESFEN 195 VPE ++R + K + R S + Sbjct: 201 QVPEECEALRAWYKRMQQRPSVKK 224 >4MK3-A nrPDB Length = 226 Score = 80.8 bits (198), Expect = 4e-16, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 78/199 (39%), Gaps = 20/199 (10%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIV 77 P++++V + L EKK+ Y+ NV +P GKVP + + DG V DS VI Sbjct: 30 TSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAVFDSRVIA 89 Query: 78 GLLEEKYPEPSLKTPPEFASVGSKIFGAFVTF-----------LKSKDANDGSEKALVDE 126 + P L + + + A + + ++ SE + + Sbjct: 90 EYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESERSESWVQRQ 149 Query: 127 LEALENHLKTHSG-----PFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVR 181 ++ L S + G T D+++ L +L+ + + + + ++ Sbjct: 150 RSKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLDF---RFPDIAWRDRHPNLV 206 Query: 182 NYAKALFSRESFENTKAKK 200 + + + R+SF +T+ + Sbjct: 207 AFQEKIEKRQSFIDTEPPR 225 >3VWX-A nrPDB Length = 222 Score = 80.0 bits (196), Expect = 7e-16, Method: Composition-based stats. Identities = 47/206 (22%), Positives = 86/206 (41%), Gaps = 28/206 (13%) Query: 26 VLLTLEEKKLPYKTHLINVSDK---PQWFLDISPEGKVPVVKLDGKWVADSDVIVGLL-- 80 LLTL+ LP++ ++N+ K + +L +P+ VP ++ DG + DS I+ L Sbjct: 18 CLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDSHAIMAYLVS 77 Query: 81 -----EEKYPEPSLK----TPPEFASVGSKIFGAFVT-----FLKSKDANDGSE-KALVD 125 + YP+ LK + G G F +++ + ++V+ Sbjct: 78 KYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIPQHQIDSIVE 137 Query: 126 ELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAK 185 LE+ LK + ++AG+ +T D S+ + L VA + + K Sbjct: 138 SYGFLESFLKNN--KYMAGDHLTIADFSIVTSVTSL-VAFAEIDQ----SKFPKLSAWLK 190 Query: 186 ALFSRESFENTK-AKKEIVVAGWESK 210 +L S +E A + +VA +SK Sbjct: 191 SLQSLPFYEEANGAGAKQLVAMVKSK 216 >3PR8-A nrPDB Length = 229 Score = 78.9 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 34/205 (16%), Positives = 70/205 (34%), Gaps = 20/205 (9%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYP 85 V L L EK L ++ PQ ++SP GKVPV++ + +++++ VI+ +E+ Sbjct: 17 VKLALLEKGLTFEEVTFYGGQAPQAL-EVSPRGKVPVLETEHGFLSETSVILDYIEQTQG 75 Query: 86 EPSLKTPPEFASVGSK-IFGAFVTFLK----------------SKDANDGSEKALVDELE 128 +L F + + +++ + + L+ Sbjct: 76 GKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVEPLIKEKARADLLAGFA 135 Query: 129 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 L+ P+VAGE++T DL + N + + + Sbjct: 136 TLKR--NGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDFLADFPQAKALLQLMG 193 Query: 189 SRESFENTKAKKEIVVAGWESKVNA 213 A KE + + + + Sbjct: 194 ENPHMPRILADKEASMPAFMEMIRS 218 >3R2Q-A nrPDB Length = 202 Score = 77.4 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 44/202 (21%), Positives = 77/202 (38%), Gaps = 26/202 (12%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIV 77 PF +++ + L EK + ++ + +P GKVPV+ +G+ DS +I Sbjct: 8 TSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIA 67 Query: 78 GLLE--EKYPEPSLKTPPEFASVG------SKIFGAFVTFLKSKD--ANDGSEKALVDEL 127 +E P + P E V I A + ++ + A SE L+ + Sbjct: 68 EYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQR 127 Query: 128 EALENHLKTHSGPFVAG----EKITAVDLSLAPKLYHLEVALGHYK----NWSVPESLTS 179 E + L G V G + + +++A V +++ W V Sbjct: 128 EKINRSLDVLEGYLVDGTLKTDTVNLATIAIA-----CAVGYLNFRRVAPGWCV--DRPH 180 Query: 180 VRNYAKALFSRESFENTKAKKE 201 + + LFSRESF T+ K Sbjct: 181 LVKLVENLFSRESFARTEPPKA 202 >4YH2-A nrPDB Length = 222 Score = 77.4 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 74/190 (38%), Gaps = 27/190 (14%) Query: 26 VLLTLEEKKLPYKTHLINVSDK---PQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEE 82 V LTL L Y+ +++ + +L+ +P+ VP ++ DG ++ DS I+ L Sbjct: 18 VKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVS 77 Query: 83 KYPE---PSLKTPPEFASVGSKI-------FGAFVTFLKSKDANDGSEK-------ALVD 125 KY + K P + A V ++ F + + G K A+++ Sbjct: 78 KYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIE 137 Query: 126 ELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAK 185 + +E LK ++AG ++T D SL + LE + + + K Sbjct: 138 IYDFVETFLKGQD--YIAGNQLTIADFSLVSSVASLEA----FVALD-TTKYPRIGAWIK 190 Query: 186 ALFSRESFEN 195 L +E Sbjct: 191 KLEQLPYYEE 200 >5EY6-A nrPDB Length = 217 Score = 77.4 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 32/198 (16%) Query: 25 RVLLTLEEKKLPYKTHLINVSD---KPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 RVL+TL EK +P++ +++S K +L I P G+VP + + + +S I + Sbjct: 17 RVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESISLFESRSICRYVC 76 Query: 82 EKYPEPSLK-----TPPEFASVGSKIFGAFVTFLKSKDAN-------------------D 117 EKY + K P E AS+ + +F S A Sbjct: 77 EKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVIK 136 Query: 118 GSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESL 177 +E+ L L+ E L F+AG++ T DLS P +L A + S Sbjct: 137 QNEEKLGKVLDIYEQRLGES--RFLAGDEFTFADLSHLPNGDYLVNATDKGHLF---TSR 191 Query: 178 TSVRNYAKALFSRESFEN 195 +V + + RES++ Sbjct: 192 ENVGRWWNEISDRESWKK 209 >4PNG-A nrPDB Length = 229 Score = 77.0 bits (188), Expect = 6e-15, Method: Composition-based stats. Identities = 41/190 (21%), Positives = 75/190 (39%), Gaps = 27/190 (14%) Query: 26 VLLTLEEKKLPYKTHLINVSDK---PQWFLDISPEGKVPVVKLDGKWVADSDVIVGLL-- 80 V LTL ++PY+ +N K + FL +P+ VP ++ DG ++ DS I+ L Sbjct: 24 VKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVS 83 Query: 81 -----EEKYPEPSLKTPPEFASVGSKIFGAFVTFLKS-KDANDGSEK---------ALVD 125 + YP+ L+ + + F L+S ++ A+++ Sbjct: 84 KYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKERYDAIIE 143 Query: 126 ELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAK 185 + LE L + +VAG ++T D S+ + LEV + + + K Sbjct: 144 VYDFLEKFLAGND--YVAGNQLTIADFSIISTVSSLEV----FVKVD-TTKYPRIAAWFK 196 Query: 186 ALFSRESFEN 195 L +E Sbjct: 197 RLQKLPYYEE 206 >3UAR-A nrPDB Length = 227 Score = 76.2 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 27/197 (13%) Query: 28 LTLEEKKLPYKTHLINVSDK----PQWFLDISPEGKVPVVKL-DGKWVADSDVIVGLLEE 82 + L E L ++ +++ K FL ++P+G VP ++L DG+ + + VI+ L + Sbjct: 18 IVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLDDGQVLTEDQVILQYLAD 77 Query: 83 KYPEPSLKTP----------PEFASVGSKIFGAFVTFLKSKDANDGSEKALV----DELE 128 PE L P A + ++I F F + ++ + S++ + L+ Sbjct: 78 LKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFW-NPESPEASKQIALGLLSRRLD 136 Query: 129 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 +E+ L+ GP++ G++ + D L+ L E Y + + + Y + Sbjct: 137 YVEDRLEA-GGPWLMGDRYSVADAYLSTVLGWCE-----YLKIDLSK-WPRILAYLERNQ 189 Query: 189 SRESFENTKAKKEIVVA 205 +R + + + ++ A Sbjct: 190 ARPAVQAAMKAEGLIQA 206 >6F05-A nrPDB Length = 215 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 43/201 (21%), Positives = 78/201 (38%), Gaps = 31/201 (15%) Query: 25 RVLLTLEEKKLPYKTHLINVSD---KPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 R L+TL EK + ++T +++ K +L + P G VP V + +S ++ + Sbjct: 15 RALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYVA 74 Query: 82 EKY--PEPSLK---------------------TPPEFASVGSKIFGAFVTFLKSKDANDG 118 EKY P L PP +F + + F + Sbjct: 75 EKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIKE 134 Query: 119 SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLT 178 SE+ L L+ E HL ++AG+ ++ DL+ P + +G + + Sbjct: 135 SEEKLAGVLDVYEAHL--SKSKYLAGDFVSLADLAHLPF---TDYLVGPIGKAYMIKDRK 189 Query: 179 SVRNYAKALFSRESFENTKAK 199 V + + SR +++ T AK Sbjct: 190 HVSAWWDDISSRPAWKETVAK 210 >5F07-A nrPDB Length = 213 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 46/207 (22%), Positives = 77/207 (37%), Gaps = 37/207 (17%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINV---SDKPQWFLDISPEGKVPVVKLDGKWVADS 73 + CP QRV+ L EK + + +++ K FL P G+VPVV+ + +S Sbjct: 9 VAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFES 66 Query: 74 DVIVGLLEEKYPE--PSLKT----------------PPEFASVGSKIFGAFVTFLKSKDA 115 I+ KY + P+L F + I V + Sbjct: 67 RAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQ 126 Query: 116 NDGS-----EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHL--EVALGHY 168 D E+ L L+ E L ++AG+ T DLS P +L E LGH Sbjct: 127 GDSELVRTYEEKLEKVLDVYEKRL--SKSKYLAGDSFTLADLSHLPATRYLVNEAGLGH- 183 Query: 169 KNWSVPESLTSVRNYAKALFSRESFEN 195 + + + + + + SR +++ Sbjct: 184 ----LVKDRKKLNAWWEDISSRPAWKK 206 >5A5K-A nrPDB Length = 212 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 41/213 (19%), Positives = 68/213 (31%), Gaps = 39/213 (18%) Query: 12 GAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSD---KPQWFLDISPEGKVPVVKLDGK 68 G P + +RVL+ L EK L ++ + + D K + FL +P G+VP + Sbjct: 8 GHPASIAT----RRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 Query: 69 WVADSDVIVGLLEEKYP--------------------------EPSLKTPPEFASVGSKI 102 + +S I + +Y E P +I Sbjct: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 Query: 103 FGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 F + + E L L+ E LK ++AGE T DL P + +L Sbjct: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYLL 181 Query: 163 VALGHYKNWSVPESLTSVRNYAKALFSRESFEN 195 + V + + R + E Sbjct: 182 GTPTK----KLFTERPRVNEWVAEITKRPASEK 210 >4RI7-A nrPDB Length = 215 Score = 73.5 bits (179), Expect = 7e-14, Method: Composition-based stats. Identities = 46/200 (23%), Positives = 75/200 (37%), Gaps = 29/200 (14%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSD---KPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 C RVL TL EK +P+ I++S K +L I P G+VP K + + +S I Sbjct: 13 CTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAI 72 Query: 77 VGLLEEKYPE---PSLKTPPEFASVGSKIFGA-------------FVTFLKSKDANDGS- 119 + +KY + SL + + L S D + Sbjct: 73 CRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVDEAL 132 Query: 120 ----EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPE 175 L L+ E L F+AG++ + DLS P +L K + + Sbjct: 133 IKKNVDKLAKVLDIYEQKLGQ--TRFLAGDEFSFADLSHLPNGDYL--VNSTDKGY-LFT 187 Query: 176 SLTSVRNYAKALFSRESFEN 195 S +V + + +RES++ Sbjct: 188 SRKNVNRWWTEISNRESWKK 207 >3M3M-A nrPDB Length = 210 Score = 72.0 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 80/195 (41%), Gaps = 31/195 (15%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVS---DKPQWFLDISPEGKVPVVKL-DGKWVAD 72 G+C ++ L L LPY+ +++ + + FL +P GK+PV++L DG + + Sbjct: 12 SGNC---YKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDGTCLWE 68 Query: 73 SDVIVGLL---EEKYP-EPSLKTPPE----FASVGSKIFGAFVTFLK--SKDANDGSEKA 122 S+ I+ L + P EP L+T F + + A F++ + E+ Sbjct: 69 SNAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGLPEERREEY 128 Query: 123 LV------DELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPES 176 L L+ +E L P++ GE + D++L + + + + Sbjct: 129 LKLHKRGYKALDVMEKQL--SRTPYLVGEHYSIADIALYAYTHVADE-----GGFDL-SR 180 Query: 177 LTSVRNYAKALFSRE 191 ++ + + + S Sbjct: 181 YPGIQAWMQRVQSHP 195 >2PMT-A nrPDB Length = 203 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 37/182 (20%), Positives = 70/182 (38%), Gaps = 26/182 (14%) Query: 28 LTLEEKKLPYKTHLINVSDK----PQWFLDISPEGKVPVVKLD-GKWVADSDVIVGLLEE 82 + L E L + I++ K + FL I+P+G+VPV++LD G + + IV L + Sbjct: 16 IVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTEGVAIVQYLAD 75 Query: 83 KYPEPSLKTPP---------EFASVGSKIFGAFVTFLKSKDANDG----SEKALVDELEA 129 P+ +L PP E+ + + + L S D + + L + Sbjct: 76 LKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSSDTPESYLPVVKNKLKSKFVY 135 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 + + L V G+ T D L + + + L+ +++Y + Sbjct: 136 INDVL--SKQKCVCGDHFTVADAYLFTLSQW-----APHVALDLTD-LSHLQDYLARIAQ 187 Query: 190 RE 191 R Sbjct: 188 RP 189 >1JLV-A nrPDB Length = 209 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 40/187 (21%), Positives = 73/187 (39%), Gaps = 27/187 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSDKP---QWFLDISPEGKVPVVKLDGKWVADSD 74 G P + V +T + L N+ FL I+P+ +P + +G + +S Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLVDNGFALWESR 66 Query: 75 VIVGLLEEKY---PEPSLKTPPEFASVGSKIFGAFVTFLK------------SKDANDGS 119 I L EKY + K P + A V +++ T + + AN + Sbjct: 67 AICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAKQPANAEN 126 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 EK + D ++ L L H +VAG+ +T DL++ + +VA + + Sbjct: 127 EKKMKDAVDFLNTFLDGH--KYVAGDSLTIADLTVLATVSTYDVA-----GFEL-AKYPH 178 Query: 180 VRNYAKA 186 V + + Sbjct: 179 VAAWYER 185 >1V2A-A nrPDB Length = 210 Score = 70.4 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 72/204 (35%), Gaps = 34/204 (16%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSD--KPQWFLDISPEGKVPVVKLDGKWVADSDVIV 77 P Q +L ++ + NV D + ++P+ +P + +G V +S IV Sbjct: 9 SPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLVDNGHVVWESYAIV 68 Query: 78 GLLEEKYPE---PSLKTPPEFASVGSKIFGAFVTF-----------LKSKDANDGSEKAL 123 L E Y + K P + V ++F T +K + +D + L Sbjct: 69 LYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQPSDEQMEKL 128 Query: 124 VDELEALENHLKTHSGPFVAGEKITAVDLSL---APKLYHLEVALGHYKNWSVPESLTSV 180 L+ LE + + + A + +T D+ L L L+ L + + Sbjct: 129 KGALDLLEQFVTERA--YAAADHLTVADICLLGTVTALNWLKHDLEPF---------PHI 177 Query: 181 RNYAKALFSR----ESFENTKAKK 200 R + + + + E F A Sbjct: 178 RAWLERVRAEMPDYEEFSKQVADD 201 >1AXD-A nrPDB Length = 209 Score = 70.4 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 42/198 (21%), Positives = 67/198 (33%), Gaps = 36/198 (18%) Query: 25 RVLLTLEEKKLPYKTHLINV---SDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 R LEE Y+ IN K L +P G+VP ++ ++ +S I Sbjct: 16 RCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGDLYLFESRAICKYAA 75 Query: 82 EKY-PEPSLKTPPEFASVGSK---------------------IFGAFVTFLKSKDANDGS 119 K PE + E A++ I K ++ Sbjct: 76 RKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDENL 135 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKN--WSVPESL 177 EK L LE E L ++AG+ ++ D L H+ V L + SV ++ Sbjct: 136 EK-LKKVLEVYEARLTKC--KYLAGDFLSLAD------LNHVSVTLCLFATPYASVLDAY 186 Query: 178 TSVRNYAKALFSRESFEN 195 V+ + L R S + Sbjct: 187 PHVKAWWSGLMERPSVQK 204 >1F2E-A nrPDB Length = 201 Score = 70.0 bits (170), Expect = 8e-13, Method: Composition-based stats. Identities = 33/184 (17%), Positives = 72/184 (39%), Gaps = 26/184 (14%) Query: 28 LTLEEKKLPYKTHLINV----SDKPQWFLDISPEGKVPVVKLD-GKWVADSDVIVGLLEE 82 + L E ++ +++ ++ + FL ++P GKVP + LD G+ + ++ I+ + + Sbjct: 16 IALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIAD 75 Query: 83 KYPEPSLKTPP---EFASVGSKIFGAFVTFLK----------SKDANDGSEKALVDELEA 129 + P L + + S++ F K S +A + +++ + L A Sbjct: 76 QNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNHLAA 135 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 L+ L AG + D+ L L Y + + ++ YA + Sbjct: 136 LDKELAGRD--HYAGNAFSVADIYLYVMLGW-----PAYVGIDM-AAYPALGAYAGKIAQ 187 Query: 190 RESF 193 R + Sbjct: 188 RPAV 191 >2IL3-A nrPDB Length = 221 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 65/195 (33%), Gaps = 27/195 (13%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKP---QWFLDISPEGKVPVVKLDGKWVADSDVI 76 P + V LT + L + IN+ F+ ++P+ +PV+ +G + +S I Sbjct: 12 SPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVLDDNGTIITESHAI 71 Query: 77 VGLLEEKYPE---PSLKTPPEFASV-------------GSKIFGAFVTFLKSKDANDGSE 120 + L KY + K P + A V + + F D + Sbjct: 72 MIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPEDRV 131 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 + + E LE+ L FVAG +T D S + + + + Sbjct: 132 EYVQKSYELLEDTLVDD---FVAGPTMTIADFSCISTISSI----MGVVPLEQSKH-PRI 183 Query: 181 RNYAKALFSRESFEN 195 + L +E Sbjct: 184 YAWIDRLKQLPYYEE 198 >1PN9-A nrPDB Length = 209 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 27/188 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSDKP---QWFLDISPEGKVPVVKLDGKWVADSD 74 G P + V +T + L ++ FL ++P+ +P + +G + +S Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLVDNGFALWESR 66 Query: 75 VIVGLLEEKY---PEPSLKTPPEFASVGSKIFGAFVTFLK------------SKDANDGS 119 I L EKY + K P + A V +++ T + + AN + Sbjct: 67 AIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAKQPANPEN 126 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 EK + D + L L+ + AG +T DLSLA + EVA + + + Sbjct: 127 EKKMKDAVGFLNTFLEGQE--YAAGNDLTIADLSLAATIATYEVAGFDFAPY------PN 178 Query: 180 VRNYAKAL 187 V + Sbjct: 179 VAAWFARC 186 >3M8N-A nrPDB Length = 225 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 38/205 (18%), Positives = 80/205 (39%), Gaps = 31/205 (15%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSD---KPQWFLDISPEGKVPVVKLD-GKWVADSDVIVG 78 S +V L L PY+ +++ + FL +P G+VP+++ G+++A+S+ I+ Sbjct: 15 SYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAPGRYLAESNAILW 74 Query: 79 LL---EEKYPEPSLKTPP-------EFASVGSKI--------FGAFVTFLKSKDANDGSE 120 L P+ + E ++ I L++ D E Sbjct: 75 YLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQTHALEDWLE 134 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 + L+ +ENHLKT+ + A ++T D++L + + ++ + +V Sbjct: 135 RGYA-ALQVMENHLKTND--YFAAGQLTIADIALYGYTHVADQ-----CDFDLST-FPAV 185 Query: 181 RNYAKALFSRESFENTKAKKEIVVA 205 + + + F E + A Sbjct: 186 NAWLRRVEQTPGFITMDWTPETIAA 210 >5NR1-A nrPDB Length = 228 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 77/207 (37%), Gaps = 34/207 (16%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL----DGKWVADSDVI 76 P S++V L L EK+LP+ + + P F ++P G PV+ + ++ I Sbjct: 14 PASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRAI 73 Query: 77 VGLLEEKYPEPSL--KTPPEFASVGSKIFGAFVTFLKSKDANDGSE-------------- 120 + +EE EP L + P E A ++ F ++ Sbjct: 74 LEHIEETETEPPLLGRDPAERAEAR-RLLQWFDRKFDNEVNGFLLHEKMEKRLLRMGAPD 132 Query: 121 -KALVDELEALENHLKT-----HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVP 174 AL EAL HL + ++AG +++ D + A L ++ VP Sbjct: 133 LAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHLSVIDYFG------DVP 186 Query: 175 -ESLTSVRNYAKALFSRESFENTKAKK 200 + + + + L SR F A + Sbjct: 187 WKDFQAAKTWYMKLKSRPCFRPILADR 213 >2GDR-A nrPDB Length = 202 Score = 68.5 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 33/195 (16%), Positives = 77/195 (39%), Gaps = 28/195 (14%) Query: 28 LTLEEKKLPYKTHLINVSDK----PQWFLDISPEGKVPVVKL-DGKWVADSDVIVGLLEE 82 + L E L ++ ++++ K Q +L+++P G VP ++L DG+ + + IV + + Sbjct: 16 IALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTEGPAIVQYVAD 75 Query: 83 KYPEPSLKTP------PEFASVGSKIFGAFVT---FLKSKDANDGSEKALVDELEALENH 133 + P L + I L + ++D + A+ L Sbjct: 76 QVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPLFNPASSDEWKNAVRQS---LNTR 132 Query: 134 LKTHSG-----PFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 L + P++ G++++ D+ L L Y N + S++ + + Sbjct: 133 LGQVARQLEHAPYLLGDQLSVADIYLFVVLGW-----SAYVNIDL-SPWPSLQAFQGRVG 186 Query: 189 SRESFENTKAKKEIV 203 RE+ ++ + ++ Sbjct: 187 GREAVQSALRAEGLI 201 >3MAK-A nrPDB Length = 209 Score = 66.6 bits (161), Expect = 7e-12, Method: Composition-based stats. Identities = 37/188 (19%), Positives = 74/188 (39%), Gaps = 27/188 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSDKP---QWFLDISPEGKVPVVKLDGKWVADSD 74 G P + V++T + + L+N+ FL I+P+ +P + +G + +S Sbjct: 9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDNGFALWESR 67 Query: 75 VIVGLLEEKYPE---PSLKTPPEFASVGSKIFGAFVTFLKSKD------------ANDGS 119 I L EKY + K P + A + +++ T +S A+ + Sbjct: 68 AIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPEA 127 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 K + E L L+ + AG+ +T D++L + EVA + + + + Sbjct: 128 FKKIEAAFEFLNTFLEGQD--YAAGDSLTVADIALVATVSTFEVA-----KFEISK-YAN 179 Query: 180 VRNYAKAL 187 V + + Sbjct: 180 VNRWYENA 187 >3GH6-A nrPDB Length = 210 Score = 66.2 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 73/192 (38%), Gaps = 28/192 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLI-NVSDKPQW---FLDISPEGKVPVVKLDGKWVADS 73 G P + VL+T + + + I N + Q+ +L I+P+ +P + G + +S Sbjct: 8 GSAP-CRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWES 66 Query: 74 DVIVGLLEEKYPEPSLKTPPEFAS---VGSKIFGAFVTFLKS------------KDANDG 118 I+ L EKY + P + + +++ T KS K AN+ Sbjct: 67 RAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFLKKPANEE 126 Query: 119 SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLT 178 + K + E L L+ + AG + D++ + +VA +K + Sbjct: 127 NYKKIEVAFEFLNTFLE--GQTYSAGGDYSLADIAFLATVSTFDVAGFDFKRY------A 178 Query: 179 SVRNYAKALFSR 190 +V + + Sbjct: 179 NVARWYENAKKL 190 >5ZWP-A nrPDB Length = 208 Score = 66.2 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 74/188 (39%), Gaps = 27/188 (14%) Query: 18 GDCPFSQRVLLTLEEKKLPYKTHLINVSDKP---QWFLDISPEGKVPVVKLDGKWVADSD 74 G P + VL+T + + L+N+ FL I+P+ +P + + +S Sbjct: 8 GSAP-CRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGDFALWESR 66 Query: 75 VIVGLLEEKYPEPS---LKTPPEFASVGSKIFGAFVTFLKSKD------------ANDGS 119 I+ L EKY + K P + A + +++ T KS A+ Sbjct: 67 AIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPADPEL 126 Query: 120 EKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTS 179 K + + L LK H + AG+ +T DL+L + EVA ++ + + + Sbjct: 127 FKKIETAFDFLNTFLKGHE--YAAGDSLTVADLALLASVSTFEVA-----SFDISK-YPN 178 Query: 180 VRNYAKAL 187 V + L Sbjct: 179 VAKWYANL 186 >1YQ1-A nrPDB Length = 208 Score = 65.8 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 70/197 (35%), Gaps = 26/197 (13%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYP 85 + L + ++ +N D +P ++PV+ +DG + S I+ L K+ Sbjct: 18 IRLLFHLAGVQFEEVRMNPDQTWLDIKDSTPMKQLPVLNIDGFELPQSGAILRYLARKF- 76 Query: 86 EPSLKTPPEFASVGS--KIFGAFVTFLKSKDAN-------DGSEK--------ALVDELE 128 + KTP E A V + +F F+ K A + EK A Sbjct: 77 GFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSAEEVEKFRSEFFLPARNTYFN 136 Query: 129 ALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 L L+ + F+ G IT DL + L + L +Y + T + + + Sbjct: 137 ILNGLLEKSNSGFLIGSDITFADLVVVDNL----LTLKNYGLFD-ESEFTKLAALREKVN 191 Query: 189 S---RESFENTKAKKEI 202 S + + + E Sbjct: 192 SYPGIKEYIAKRPVTEY 208 >4MPF-A nrPDB Length = 266 Score = 64.6 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 79/212 (37%), Gaps = 31/212 (14%) Query: 26 VLLTLEEKKLPYKTHLINV---SDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEE 82 V + ++ +P + +++ K + FL I+ GK+P +K + +S I+ L Sbjct: 39 VYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSC 98 Query: 83 KYPEPSLKTPPEFASV------------------GSKIFGAFVTFLKS----KDANDGSE 120 KY P P + + G ++ + L K+ + + Sbjct: 99 KYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNR 158 Query: 121 KALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 A+ L+ LE+ PF+AG+++T DL +L ++ + + E + Sbjct: 159 TAMDQALQWLEDKF-LGDRPFLAGQQVTLADLMALEEL--MQPVAL---GYELFEGRPRL 212 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGWESKVN 212 + + + E + I+++ E Sbjct: 213 AAWRGRVEAFLGAELCQEAHSIILSILEQAAK 244 >5F05-A nrPDB Length = 212 Score = 64.3 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 68/200 (34%), Gaps = 31/200 (15%) Query: 24 QRVLLTLEEKKLPYKTHLINV---SDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLL 80 QRVL TL EK++ ++ +N+ K + + ++P G+VP + +S I + Sbjct: 15 QRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYV 74 Query: 81 EEKYP----------------------EPSLKTPPEFASVGSKIFGAFVTFLKSKDANDG 118 +Y E P V ++F Sbjct: 75 AHQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKPVFGLPTDAALVAE 134 Query: 119 SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLT 178 +E L L+ E L ++A + T DL P + AL + + +S Sbjct: 135 TEVTLGKVLDVYEARLSQS--KYLASDSFTLADLHHLPNIQ----ALLGTPSKKLFDSRP 188 Query: 179 SVRNYAKALFSRESFENTKA 198 V + ++ R ++ A Sbjct: 189 HVSAWVASITGRPAWGKVLA 208 >3C8E-A nrPDB Length = 288 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 77/204 (37%), Gaps = 31/204 (15%) Query: 21 PFSQRVLLTLEE------KKLPYKTHLINVSDKPQW---FLDISPEGKVPVV---KLDGK 68 P Q+V + LEE Y LI + D Q+ F++++P K+P + + Sbjct: 53 PNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPP 112 Query: 69 W-VADSDVIVGLLEEKYPEPSLKTPP----------EFASVGSKIFGAFVTFLK-SKDAN 116 V +S I+ L EK+ + + G F F + Sbjct: 113 IRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKI 172 Query: 117 DGSEKALVDE----LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGH-YKNW 171 + + E L+ L+ L H FVAG++ T D+++ P ++ + + + Sbjct: 173 EYAINRFTMEAKRLLDVLDKQLAQH--KFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEF 230 Query: 172 SVPESLTSVRNYAKALFSRESFEN 195 S V+ +AK + R + + Sbjct: 231 LDAGSYKHVQRWAKEVGERPAVKR 254 >5F0G-A nrPDB Length = 215 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 74/183 (40%), Gaps = 26/183 (14%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADSDVIVGL 79 + V++ + L L+N + Q F+ ++P+ +P + +G + +S I Sbjct: 12 CRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVY 71 Query: 80 LEEKY--PEPSLKTPPEFASVGSK--------IFGAFVTFL-----KSKDANDGSEKALV 124 L EKY + L P+ +V ++ ++ +F + K +D K + Sbjct: 72 LVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTGKPGSDEDLKRIE 131 Query: 125 DELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYA 184 L+ L+ +VAG+++T D+++ + EV+ + +S +V + Sbjct: 132 TAFGFLDTFLEGQE--YVAGDQLTVADIAILSTVSTFEVSEFDFSKYS------NVSRWY 183 Query: 185 KAL 187 Sbjct: 184 DNA 186 >3GX0-A nrPDB Length = 215 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 76/199 (38%), Gaps = 37/199 (18%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVK-----LDGKW--V 70 P ++ L LEE +L Y+ +++ Q+ FL ISP K+P + G+ + Sbjct: 10 PNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPADGGEPLSL 69 Query: 71 ADSDVIVGLLEEKYPEPSLKTPPEFASVGS-----KIFGAFVTFLKSKDANDGSEKALVD 125 +S I+ L EK L + ++ G ++ N + + + Sbjct: 70 FESGAILLYLAEK-TGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQTIPY 128 Query: 126 ELEALE-------NHLKTH--SGPFVAGEKITAVDLSLAPKLYHL---EVALGHYKNWSV 173 +E + + L + P++ GE + D++ P + + L Y Sbjct: 129 AIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAWTRQRIDLAMY----- 183 Query: 174 PESLTSVRNYAKALFSRES 192 +V+N+ + + SR + Sbjct: 184 ----PAVKNWHERIRSRPA 198 >4Q5F-A nrPDB Length = 218 Score = 60.0 bits (144), Expect = 7e-10, Method: Composition-based stats. Identities = 38/190 (20%), Positives = 75/190 (39%), Gaps = 23/190 (12%) Query: 27 LLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYPE 86 L + + ++ + + D P +P G++P++++DG+ +A S I L ++ Sbjct: 31 RLIFHQAGVKFEDNRLKREDWPA-LKPKTPFGQLPLLEVDGEVLAQSAAIYRYLGRQF-G 88 Query: 87 PSLKTPPEFASVGSKI--FGAFVTFL--------------KSKDANDGSEKALVDELEAL 130 + KTP E A V S F F+ L K K + + A L L Sbjct: 89 LAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKEKVLKEVAVPARDKHLPLL 148 Query: 131 ENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFSR 190 E L ++ G+ +T DL + L E + + + L ++ Y + + Sbjct: 149 EKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDF----LSGHLQ-LKKYIEHVREL 203 Query: 191 ESFENTKAKK 200 + + A++ Sbjct: 204 PNIKKWIAER 213 >1U3I-A nrPDB Length = 211 Score = 60.0 bits (144), Expect = 7e-10, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 74/184 (40%), Gaps = 23/184 (12%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG-----KWVADSDVIV 77 ++ + +TL + Y+ I+ D P+ I P G++P VK+ KW+ +S I Sbjct: 17 AESIRMTLVAAGVDYEDERISFQDWPKIKPTI-PGGRLPAVKVTDDHGHVKWMLESLAIA 75 Query: 78 GLLEEKYPEPSLKTPPEFASVGSKIFGA-------FVTFLKSKDANDGSEKALVDE---- 126 + +K+ +T E+ SV I A T +K ++ + K +++ Sbjct: 76 RYMAKKH-HMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITKEILNGKVPV 134 Query: 127 -LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAK 185 + LK +G G+K+T DL L + H+ + + + + + Sbjct: 135 LFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGF----LTGKYPEIHKHRE 190 Query: 186 ALFS 189 L + Sbjct: 191 NLLA 194 >3LSZ-A nrPDB Length = 225 Score = 59.6 bits (143), Expect = 9e-10, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 65/206 (31%), Gaps = 43/206 (20%) Query: 23 SQRVLLTLEEKKLPYKTHLI--------------NVSDKPQWFLDISPEGKVPVVKLDGK 68 + R L L E LP++ + ++ +L ++P G++P ++ +G Sbjct: 13 ASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQIPCLEEEGL 72 Query: 69 WVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAND----------- 117 + +S I + + L E + F A + Sbjct: 73 ILTESLAITLHI-ARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQRSGGGT 131 Query: 118 --GSEKA-------LVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHY 168 + A L L LE H ++ G + T DL+LA L H Sbjct: 132 SPEGQAAIAIAAERLRRPLARLERHFAAED--YLVGGRFTVADLNLA---ETLRYGQAHP 186 Query: 169 KNWSVPESLTSVRNYAKALFSRESFE 194 + E +V + SR +F Sbjct: 187 A---LLEPFPAVAAWLDRCQSRPAFR 209 >1N2A-A nrPDB Length = 201 Score = 59.2 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 33/191 (17%), Positives = 66/191 (34%), Gaps = 26/191 (13%) Query: 28 LTLEEKKLPYKTHLINVSDK----PQWFLDISPEGKVPV-VKLDGKWVADSDVIVGLLEE 82 +TL E + +++ K + ++P+G+VP + DG + + I+ L + Sbjct: 16 ITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDDGTLLTEGVAIMQYLAD 75 Query: 83 KYPEPSLKTPPEFASVGSKI---------FGAFVTFLKSKDANDGSE----KALVDELEA 129 P+ L P S I T L D + + L +L+ Sbjct: 76 SVPDRQLLAPVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQY 135 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 + LK ++ G++ T D L L A N L + + + + Sbjct: 136 VNEALKDEH--WICGQRFTIADAYL---FTVLRWAYAVKLNLE---GLEHIAAFMQRMAE 187 Query: 190 RESFENTKAKK 200 R ++ + + Sbjct: 188 RPEVQDALSAE 198 >4MDC-A nrPDB Length = 252 Score = 58.1 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 44/213 (20%), Positives = 77/213 (36%), Gaps = 39/213 (18%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG-KWVADSDVIVG 78 P S+ V L L E + + + FL ++P G +PV D + + + +I Sbjct: 32 SPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCGATIISE 91 Query: 79 LLEEK----YPEPSLKTPPEFAS----------------------VGSKIFGAFVTFLKS 112 L+E + L F V +IF +T + Sbjct: 92 YLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRERIFKLQMTPDQG 151 Query: 113 KDANDGSEKALVDELEALENHLKT-----HSGPFVAGEKITAVDLSLAPKLYHLEVALGH 167 A D K L + H+K S P++AG++I+ DL+ A + L+ Sbjct: 152 GGAPDS--KILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAAAISVLDYLGE- 208 Query: 168 YKNWSVPESLTSVRNYAKALFSRESFENTKAKK 200 +W + + + + L SR SF A++ Sbjct: 209 -IDW---SDAPTAKEWYQRLKSRPSFRPLLAER 237 >1B48-A nrPDB Length = 221 Score = 57.7 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 51/146 (34%), Gaps = 19/146 (13%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISP--EGKVPVVKLDGKWVADSDVIVGLLEEK 83 + L + ++ + ++ + G+VP+V++DG + + I+ L K Sbjct: 18 IRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEIDGMMLTQTRAILSYLAAK 77 Query: 84 YPEPSLKTPPEFASVGSKIFGAF---------VTFLKSKDANDGSE-----KALVDELEA 129 Y +L V ++ V K+ + S +A Sbjct: 78 Y---NLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESYDLILSRAKTRYFPV 134 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLA 155 E LK H F+ G +++ D+ L Sbjct: 135 FEKILKDHGEAFLVGNQLSWADIQLL 160 >2CA8-A nrPDB Length = 211 Score = 57.7 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 70/189 (37%), Gaps = 33/189 (17%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG-----KWVADSDVIV 77 ++ + +TL + Y+ I+ D P+ I P G++P VK+ KW+ +S I Sbjct: 17 AESIRMTLVAAGVNYEDERISFQDWPKIKPTI-PGGRLPAVKITDNHGHVKWMVESLAIA 75 Query: 78 GLL-----------EEKYPEPSLKTPPEFASVGSKIFGAFVTFL-KSKDANDGSEKALVD 125 + EE Y L E + + L K ++ K +++ Sbjct: 76 RYMAKKHHMMGGTEEEYYNVEKLIGQAE------DLEHEYYKTLMKPEEEKQKIIKEILN 129 Query: 126 E-----LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSV 180 L+ + LK +G G+K+T DL L + H+ + + + Sbjct: 130 GKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEF----LTGKYPEI 185 Query: 181 RNYAKALFS 189 + + L + Sbjct: 186 HKHRENLLA 194 >4FQU-A nrPDB Length = 313 Score = 56.2 bits (134), Expect = 9e-09, Method: Composition-based stats. Identities = 41/226 (18%), Positives = 77/226 (34%), Gaps = 52/226 (23%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLI----------------------NVSDKPQWFLDIS-- 55 CP++ RVL+ K L + + + + + + Sbjct: 53 CPWAHRVLIMRALKGLE-EMISVSMVNAYMGENGWTFLPGDDVVPDSINGADYLYQVYTA 111 Query: 56 --P----EGKVPVV--KLDGKWVA-DSDVIVGLLEEKYPE----PSLKTPPEFASVGSKI 102 P +P++ K++ + + +S I+ +L + + P P EF +I Sbjct: 112 ADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRI 171 Query: 103 FGAFVTFLKSKD-------ANDGSEKAL---VDELEALENHLKTHSGPFVAGEKITAVDL 152 L + + E+A D L+ LE HL ++ G+++T D+ Sbjct: 172 NARVYETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLT--GREWLVGDRLTEADI 229 Query: 153 SLAPKLYHLEVAL-GHYK-NWSVPESLTSVRNYAKALFSRESFENT 196 L P L + GH+K N ++ L S E T Sbjct: 230 RLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLASHERVAPT 275 >3M1G-A nrPDB Length = 362 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 46/226 (20%), Positives = 78/226 (34%), Gaps = 52/226 (23%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVS----DKPQWFLDISP------------------- 56 CP++ R ++T L + ++ D W D+ P Sbjct: 70 CPWAHRTVITRRLLGLE-NVISLGLTGPTHDVRSWTFDLDPNHLDPVLQIPRLQDAYFNR 128 Query: 57 ------EGKVPVV--KLDGKWVAD---SDVIV------GLLEEKYPEPSLKTP-PEFASV 98 VP + + K V + S I E P E A V Sbjct: 129 FPDYPRGITVPALVEESSKKVVTNDYPSITIDFNLEWKQFHREGAPNLYPAELREEMAPV 188 Query: 99 GSKIFGAF------VTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDL 152 +IF F S++A++ + K L L+ LE+ L + ++ G+ IT D+ Sbjct: 189 MKRIFTEVNNGVYRTGFAGSQEAHNEAYKRLWVALDWLEDRL--STRRYLMGDHITEADI 246 Query: 153 SLAPKLYHLEVAL-GHYK-NWSVPESLTSVRNYAKALFSRESFENT 196 L P L + GH+K + + ++ Y + LF F +T Sbjct: 247 RLYPTLVRFDAVYHGHFKCGRNKITEMPNLWGYLRDLFQTPGFGDT 292 >2C3Q-A nrPDB Length = 247 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 69/205 (33%), Gaps = 37/205 (18%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDK---PQWFLDISPEGKVPVVKLDGKWVADSDVIVGL 79 + V + ++ +P++ ++++ F ++P KVP +K + +S I+ Sbjct: 21 CRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLY 80 Query: 80 LEEKYPEPSLKTPPEFASVG-----------------------SKIFGAFVTFLKSKDAN 116 L KY P P + + +F F+ S Sbjct: 81 LTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTL 140 Query: 117 DGSEKALVDELEALEN-HLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPE 175 + L L+ LE+ L+ + F+ G I+ DL +L H A V E Sbjct: 141 AATLAELDVTLQLLEDKFLQNKA--FLTGPHISLADLVAITELMHPVGA-----GCQVFE 193 Query: 176 SLTSVRNY---AKALFSRESFENTK 197 + + +A + F+ Sbjct: 194 GRPKLATWRQRVEAAVGEDLFQEAH 218 >1GUL-A nrPDB Length = 222 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 33/207 (15%), Positives = 68/207 (32%), Gaps = 33/207 (15%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISP--EGKVPVVKLDGKWVADSDVIVGLLEEK 83 V L + + + ++ D + +VP+V++DG + + I+ + +K Sbjct: 19 VRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADK 78 Query: 84 YP-------EPSLKTPPEFASVGSKIFGAFVTFLKSKDANDG----SEKALVDELEALEN 132 + E +L ++ FLK D ++KA++ E Sbjct: 79 HNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEK 138 Query: 133 HLKTHSGPFVAGEKITAVDLSL----------APKLYHLEVALGHY--KNWSVPESLTSV 180 L+ H F+ G +++ D+ L P + L Y K ++P Sbjct: 139 ILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPT----- 193 Query: 181 RNYAKALFSRESFENTKAKKEIVVAGW 207 K S + + V + Sbjct: 194 ---IKRFLEPGSKKKPPPDEIYVRTVY 217 >1VF1-A nrPDB Length = 229 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 31/186 (16%), Positives = 65/186 (34%), Gaps = 24/186 (12%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLD--ISPEGKVPVVKLDGKWVADSDVIVGLLEEK 83 + L + ++ + ++ + L I +VP+V++DG + + I+ + K Sbjct: 19 IRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEIDGMKLVQTRAILNYIAGK 78 Query: 84 YPEPSLKTPPEFASVGSKIFGAFVT----------FLKSKDANDG----SEKALVDELEA 129 Y +L ++ FL ++D EKA A Sbjct: 79 Y---NLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQCAFVVEKATSRYFPA 135 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 E LK H F+ G +++ D+ L + +E K ++ + K + S Sbjct: 136 YEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEE-----KKSDALSGFPLLQAFKKRISS 190 Query: 190 RESFEN 195 + + Sbjct: 191 IPTIKK 196 >6GZF-A nrPDB Length = 341 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 32/226 (14%), Positives = 74/226 (32%), Gaps = 51/226 (22%) Query: 20 CPFSQRVLLTLEEKKLPY--KTHLINVSDKP------------------------QWFLD 53 CP++ R L+T K L +++ + ++ Sbjct: 64 CPWAHRTLVTRTLKGLEDAISVSVVDPYRAEDGWQFTPEKEGCTHDHVHDVDYLRELYVR 123 Query: 54 ISP----EGKVPVV---KLDGKWVADSDVIVGLLEEKYPEPSLKT----PPEFASVGSKI 102 +P VPV+ + D +S+ I+ + + ++ E + T P + +I Sbjct: 124 AAPDVTCRVTVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYPEGYQEKVDQI 183 Query: 103 FGAFVTFLKSK----------DANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDL 152 + + + D + L L ++ L ++AG+++T D+ Sbjct: 184 IDNIYEPINNGVYRAGFATEQEPYDEAVAELFGALAHWDDVLADQ--RYLAGDRLTEADI 241 Query: 153 SLAPKLYHLEVAL-GHY-KNWSVPESLTSVRNYAKALFSRESFENT 196 ++ L + H+ N ++ Y + L+ T Sbjct: 242 AMFTTLVRFDNVYHTHFMCNVQYIREFDNLWPYLRDLYQTHGIAET 287 >2GLR-A nrPDB Length = 209 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 68/200 (34%), Gaps = 22/200 (11%) Query: 16 VLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDV 75 V G C + R+LL + + + I+ + G++P + + S+ Sbjct: 10 VRGRCE-AMRMLLADQGQSWKEEVVTIDTWMQG-LLKPTCLYGQLPKFEDGDLTLYQSNA 67 Query: 76 IVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSK----------DANDGSEKALVD 125 I+ L L + + + V L+ K + + KAL Sbjct: 68 ILRHLGRS---LGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPG 124 Query: 126 ELEALENHLKTHSG--PFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNY 183 L+ E L + G F+ G++I+ D +L L +V ++ + Y Sbjct: 125 HLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAP-----GCLDNFPLLSAY 179 Query: 184 AKALFSRESFENTKAKKEIV 203 L +R + + E V Sbjct: 180 VARLSARPKIKAFLSSPEHV 199 >3BBY-A nrPDB Length = 215 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 55/164 (33%), Gaps = 23/164 (14%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGK---VPVVKLDGKWVADSDVI 76 P+ + L+EK L + I++ G+ VP++++D +++S I Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAI 76 Query: 77 VGLLEEKYPEPS-----LKTPPEFASV--------------GSKIFGAFVTFLKSKDAND 117 LE+++ P+ A + V K Sbjct: 77 AEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGAKKAPLT 136 Query: 118 GSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHL 161 KA ++L A+ HL P + G + D LA + L Sbjct: 137 AEGKASAEKLFAMAEHLLVLGQPNLFG-EWCIADTDLALMINRL 179 >1G6W-A nrPDB Length = 261 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 39/238 (16%), Positives = 69/238 (28%), Gaps = 69/238 (28%) Query: 22 FSQR-------VLLTLEEKKLPYKTHLINV---SDKPQWFLDISPEGKVPVVK---LDGK 68 FS R V + L E Y T ++ + F+ ++P +VP + +D Sbjct: 24 FSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNL 83 Query: 69 WVADSDVIVGLLEEKYPE----PSLKTPPEFASVGSKIF--------------GAFVTFL 110 + +S I+ L KY + P L + + + Sbjct: 84 SIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYF 143 Query: 111 KSKDANDGSEK--------------ALVDELEALENHLKT-------------HSGPFVA 143 S+ E+ AL + EAL L T F Sbjct: 144 HSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFD 203 Query: 144 ------GEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFSRESFEN 195 G+K+T DL+ P ++ ++ V + K + R + Sbjct: 204 YPVWLVGDKLTIADLAFVPWNNVVDRI-----GINIKIEFPEVYKWTKHMMRRPAVIK 256 >4IKH-A nrPDB Length = 244 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 39/201 (19%), Positives = 72/201 (35%), Gaps = 33/201 (16%) Query: 21 PFSQRVLLTLEEKKLPYKTHLINVSDKPQ---WFLDISPEGKVPVVKL----DGKWV--A 71 P +V + LEE LPY+ H ++ + Q FL +SP K+P + + + Sbjct: 31 PNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALF 90 Query: 72 DSDVIVGLLEEKYPEPSLKTP------------------PEFASVGSKIFGAF-VTFLKS 112 +S I+ L +K + + P F VG F F + Sbjct: 91 ESGAILIYLADKSGQLLAQESAARYETIQWLMFQMGGIGPMFGQVG--FFNKFAGREYED 148 Query: 113 KDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWS 172 K + L L+ HL ++ GE+ T D++ P + +L + Sbjct: 149 KRPLERYVNEAKRLLGVLDKHLG--GREWIMGERYTIADIATFPWIRNLIGFYEAGELVG 206 Query: 173 VPESLTSVRNYAKALFSRESF 193 + ++ V+ +R + Sbjct: 207 I-DNFPEVKRVLAKFVARPAV 226 >2VCV-A nrPDB Length = 222 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 28/191 (14%), Positives = 68/191 (35%), Gaps = 34/191 (17%) Query: 26 VLLTLEEKKLPYKTHLIN-------VSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVG 78 + L + ++ I + + +VP+V++DG + + I+ Sbjct: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQ-----QVPMVEIDGMKLVQTRAILN 73 Query: 79 LLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLK--------SKDANDGSEKALVDE---- 126 + KY +L ++ + L + ++ AL+ E Sbjct: 74 YIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKS 130 Query: 127 --LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYA 184 A E L++H ++ G K++ D+SL LY++E + S+ + ++ Sbjct: 131 RYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-----DSSLISNFPLLKALK 185 Query: 185 KALFSRESFEN 195 + + + + Sbjct: 186 TRISNLPTVKK 196 >2PVQ-A nrPDB Length = 201 Score = 54.2 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 51/141 (36%), Gaps = 18/141 (12%) Query: 28 LTLEEKKLPYKTHLINVSDK----PQWFLDISPEGKVPVVKLD-GKWVADSDVIVGLL-- 80 + L E LPY+ +++ K + ++P G VP +++ G + + I+ + Sbjct: 16 IILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPGTVITQNAAILQYIGD 75 Query: 81 -EEKYPEPSLKTPPEFASVG------SKIFGAFVTFLK---SKDANDGSEKALVDELEAL 130 + E A + S + AF S++A G + L L Sbjct: 76 HSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANINRRLGQL 135 Query: 131 ENHLKTHSGPFVAGEKITAVD 151 E L + + G+ T D Sbjct: 136 EAMLSDKNA-YWLGDDFTQPD 155 >4PTS-A nrPDB Length = 348 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 45/226 (19%), Positives = 73/226 (32%), Gaps = 52/226 (23%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINV----SDKPQWFLDISPEGKVPVVKL---------- 65 CP++ R L+ L + + DK W D+ P G PV+ + Sbjct: 56 CPWANRTLIVRRLLGLE-NVLSLGLCGPTHDKNSWTFDLDPGGVDPVLGIPRLKDAYEKR 114 Query: 66 -----DGKWVADSDVIV--GLLEEKYP----------------EPSLKTPPEFASVGSKI 102 G V I ++ +P P + ++ Sbjct: 115 FPGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAPQLYPEHLRAEIDEV 174 Query: 103 FGAFVT----------FLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDL 152 T F S+DA D + L +L+ L L ++ G+ IT D+ Sbjct: 175 SKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQ--RYLVGDTITEADV 232 Query: 153 SLAPKLYHLEVAL-GHYK-NWSVPESLTSVRNYAKALFSRESFENT 196 L L + GH+K N S + + YA+ LF F +T Sbjct: 233 RLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGFGDT 278 >1F3B-A nrPDB Length = 222 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 69/189 (36%), Gaps = 30/189 (15%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEG-----KVPVVKLDGKWVADSDVIVGLL 80 + L + ++ I P+ + +G +VP+V++DG +A + I+ + Sbjct: 18 IRWLLAAAGVEFEEKFI---QSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYI 74 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFLK--------SKDANDGSEKALVDE------ 126 KY L ++ + L ++ AL + Sbjct: 75 ATKY---DLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRY 131 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKA 186 L A E LK+H ++ G ++T VD+ L L ++E + S+ ++ + Sbjct: 132 LPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEE-----FDASLLTPFPLLKAFKSR 186 Query: 187 LFSRESFEN 195 + S + + Sbjct: 187 ISSLPNVKK 195 >3I6A-A nrPDB Length = 222 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 57/156 (36%), Gaps = 25/156 (16%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEG-----KVPVVKLDGKWVADSDVIVGLL 80 L + ++ I + + +G +VP+V++DG + + I+ + Sbjct: 19 TRWLLAAAGVEFEEKFI---KSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFLK--------SKDANDGSEKALVDE------ 126 KY +L ++ + L ++ AL+ E Sbjct: 76 ASKY---NLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKDAKLALIKEKIKNRY 132 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 A E LK+H ++ G K++ D+ L LY++E Sbjct: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >4G0L-A nrPDB Length = 328 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 35/228 (15%), Positives = 75/228 (32%), Gaps = 55/228 (24%) Query: 20 CPFSQRVLLTLEEKKL-PYKTHLI---------------------NVSDKPQWFLDIS-- 55 CP++ R L+ + K L P+ + + + + ++ + Sbjct: 63 CPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNEFLYQLYLH 122 Query: 56 --PE----GKVPVVKLDGKWVA----DSDVIVGLLEEKYPEPSLK----TPPEFASVGSK 101 P VPV+ D K +S I+ + + K PP + + Sbjct: 123 ADPHYSGRVTVPVL-WDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDE 181 Query: 102 IFGAFV----------TFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVD 151 + G F S++A D + + + L LE L H ++ G ++T D Sbjct: 182 LNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQH--RYLTGNQLTEAD 239 Query: 152 LSLAPKLYHLEVALGHYKNWS---VPESLTSVRNYAKALFSRESFENT 196 + L L + + + + L ++ + + ++ T Sbjct: 240 IRLWTTLVRFDPVYVTHFKCDKHRISDYL-NLYGFLRDIYQMPGIAET 286 >3PPU-A nrPDB Length = 352 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 32/234 (13%), Positives = 76/234 (32%), Gaps = 58/234 (24%) Query: 20 CPFSQRVLLTLEEKKL------------------------PYKTHLINVSDKPQ----WF 51 CP++ R L+ + K L P+ + + Q + Sbjct: 86 CPWATRTLIVRKLKGLEDFIGVTVVSPRMGSNGWPFANVDPFPAADSDPLNNAQHVKDLY 145 Query: 52 LDISP----EGKVPVV--KLDGKWV-ADSDVIVGLLEEKYPEPSLKT-------PPEFAS 97 L + P VPV+ K G V +S I+ + + + P + Sbjct: 146 LKVKPDYDGRFTVPVLWDKHTGTIVNNESSEIIRMFNTAFNHLLPEDKAKLDLYPESLRA 205 Query: 98 VGSKIFGAFVTFLKSK-------DANDGSEKALV---DELEALENHLKTHSGPFVAGEKI 147 ++ + + E A++ + L+ LE L+ ++ G ++ Sbjct: 206 KIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIPLFESLDRLEKMLEGQD--YLIGGQL 263 Query: 148 TAVDLSLAPKLYHLEVALGHYKNWS---VPESLTSVRNYAKALF-SRESFENTK 197 T D+ L + + + + + + ++ + + L+ +F++T Sbjct: 264 TEADIRLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWMRKLYWGNPAFKDTC 317 >18GS-A nrPDB Length = 210 Score = 50.4 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 32/195 (16%), Positives = 63/195 (32%), Gaps = 23/195 (11%) Query: 23 SQRVLLTLEEKKLPY--KTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLL 80 + + L ++ + + + + G++P + + S+ I+ L Sbjct: 15 CAALRMLLADQGQSWKEEVVTVETWQEGS-LKASCLYGQLPKFQDGDLTLYQSNTILRHL 73 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSK----------DANDGSEKALVDELEAL 130 L + + + V L+ K D KAL +L+ Sbjct: 74 GRT---LGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPF 130 Query: 131 ENHLKTHSG--PFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALF 188 E L + G F+ G++I+ D +L L EV ++ + Y L Sbjct: 131 ETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAP-----GCLDAFPLLSAYVGRLS 185 Query: 189 SRESFENTKAKKEIV 203 +R + A E V Sbjct: 186 ARPKLKAFLASPEYV 200 >1PL2-A nrPDB Length = 222 Score = 50.0 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 56/156 (35%), Gaps = 25/156 (16%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEG-----KVPVVKLDGKWVADSDVIVGLL 80 L + ++ I + + +G +VP+V++DG + I+ + Sbjct: 19 TRWLLAAAGVEFEEKFI---KSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQERAILNYI 75 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFL--------KSKDANDGSEKALVDE------ 126 KY +L ++ + L ++ AL+ E Sbjct: 76 ASKY---NLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRY 132 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 A E LK+H ++ G K++ D+ L LY++E Sbjct: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >2VCT-A nrPDB Length = 222 Score = 49.6 bits (117), Expect = 9e-07, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 59/156 (37%), Gaps = 25/156 (16%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEG-----KVPVVKLDGKWVADSDVIVGLL 80 + L + ++ I + + +G +VP+V++DG + + I+ + Sbjct: 19 IRWLLAAAGVEFEEKFI---KSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFLKS--------KDANDGSEKALVDE------ 126 KY +L ++ + L + ++ AL+ E Sbjct: 76 ASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAKLALIQEKTKNRY 132 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 162 A E LK+H ++ G K++ D+ L LY++E Sbjct: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 >4LMW-A nrPDB Length = 251 Score = 49.6 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 66/205 (32%), Gaps = 51/205 (24%) Query: 14 PDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDI-SP----------EGKVPV 62 P + P + + L K L Y+T + D I +P +PV Sbjct: 16 PRQMAWGPNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYTLPV 75 Query: 63 VK--LDGKWVADSDVIVGLLEEKYPEPSLKTP--------------------PEFASVGS 100 ++ VADSD I LE YP+ P P F V + Sbjct: 76 IQDPNTKAVVADSDAIAKYLESTYPDTPRLFPEGTRAFQHAFYQLARPSVLMPIFNIVVA 135 Query: 101 KIFGAFV------------TFLKSKDANDGSE---KALVDELEALENHL---KTHSGPFV 142 +++ L K GSE AL L +++ L + Sbjct: 136 RVWKLLRPRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLL 195 Query: 143 AGEKITAVDLSLAPKLYHLEVALGH 167 G+++T DL LA L V+ G Sbjct: 196 MGDRVTFADLQLASLFIWLRVSAGE 220 >2HNL-A nrPDB Length = 225 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 66/180 (36%), Gaps = 21/180 (11%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYP 85 + L + Y+ + I D+ ++ +P G VP++ + G + +S I LL Sbjct: 42 IRLLFALANVSYEDNRI-TRDEWKYLKPRTPFGHVPMLNVSGNVLGESHAI-ELLLGGRF 99 Query: 86 EPSLKTPPEFASV------GSKIFGAFVTFLKSKDANDGS-------EKALVDELEALEN 132 E A + ++F + + K+ + E ++ L E Sbjct: 100 GLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTKKAELFRNLSESDVMPFLGRYEK 159 Query: 133 HLKTHSGPFVAGEKITAVDLSLAPKLYHL--EVALGHYKNW----SVPESLTSVRNYAKA 186 LK + + G K++ DL++ L L EV L Y + + ++ + K Sbjct: 160 FLKESTTGHIVGNKVSVADLTVFNMLMTLDDEVKLEEYPQLASFVNKIGQMPGIKEWIKK 219 >1EV4-A nrPDB Length = 221 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 53/146 (36%), Gaps = 25/146 (17%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEG-----KVPVVKLDGKWVADSDVIVGLL 80 + L + + I P+ + +G +VP+V++DG +A + I+ + Sbjct: 18 IRFLLAAAGVEFDEKFI---QSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYI 74 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFLK--------SKDANDGSEKALVDE------ 126 KY L ++ + L ++ AL + Sbjct: 75 ATKY---DLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKTALAKDRTKNRY 131 Query: 127 LEALENHLKTHSGPFVAGEKITAVDL 152 L A E LK+H ++ G K+T VD+ Sbjct: 132 LPAFEKVLKSHGQDYLVGNKLTRVDI 157 >1ZL9-A nrPDB Length = 207 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 60/156 (38%), Gaps = 21/156 (13%) Query: 55 SPEGKVPVVKLDGKWVADSDVIVGLL--------EEKYPEP---SLKTPPEFASVGSKIF 103 +P G++P +++DGK +A S I L + + E SL + S ++ + Sbjct: 48 APFGQLPFLEVDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPY 107 Query: 104 GAFVTFLKSKDANDGSEKALVDELEA----LENHLKTHSGPFVAGEKITAVDLSLAPKLY 159 V D + + E L N LK F+ G+ +T +DL++A Sbjct: 108 FYAVMGFGPGDVETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSA 167 Query: 160 HLEVALGHYKNWSVPESLTSVRNYAKALFSRESFEN 195 L G + + ++ +A+ + + + Sbjct: 168 DLIAKGGDFSKF------PELKAHAEKIQAIPQIKK 197 >5Y9Z-A nrPDB Length = 199 Score = 47.3 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 15/128 (11%) Query: 35 LPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPE 94 + Y+ H I +D P+ + P GK+PV++++G + S I L K + + KT E Sbjct: 27 IKYEDHRIEQADWPKIKPTL-PFGKIPVLEVEGLTLHQSLAIARYL-TKNTDLAGKTELE 84 Query: 95 FASVGSKI-----------FGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVA 143 V + + + LK + ND + L+ L+ +L + Sbjct: 85 QCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKE--WFI 142 Query: 144 GEKITAVD 151 G +T D Sbjct: 143 GNYVTWAD 150 >5LCZ-A nrPDB Length = 222 Score = 47.3 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 52/146 (35%), Gaps = 25/146 (17%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEG-----KVPVVKLDGKWVADSDVIVGLL 80 L + ++ I + + +G +VP+V++DG + + I+ + Sbjct: 19 TRWLLAAAGVEFEEKFI---KSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 Query: 81 EEKYPEPSLKTPPEFASVGSKIFGAFVTFLK--------SKDANDGSEKALVDE------ 126 KY +L ++ + L ++ AL + Sbjct: 76 ASKY---NLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAKTALAKDRTKNRY 132 Query: 127 LEALENHLKTHSGPFVAGEKITAVDL 152 L A E LK+H ++ G ++T VD+ Sbjct: 133 LPAFEKVLKSHGQDYLVGNRLTRVDI 158 >3KXO-A nrPDB Length = 202 Score = 46.5 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 52/144 (36%), Gaps = 16/144 (11%) Query: 22 FSQR-----VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 76 F+ R + + Y+ H I +D P+ + P GK+P++++DG + S I Sbjct: 12 FNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTL-PFGKIPILEVDGLTLHQSLAI 70 Query: 77 VGLLEEKYPEPSLKTPPE--FASVGSKIFGAFVTFLKSKDANDGSEKALVDELEALEN-H 133 L K + + T E F++ + ++ + +EL H Sbjct: 71 ARYL-TKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPH 129 Query: 134 LKTHSGPFVA------GEKITAVD 151 L ++ G +T D Sbjct: 130 LMQDLDTYLGGREWLIGNSVTWAD 153 >2AAW-A nrPDB Length = 222 Score = 46.5 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 31/188 (16%), Positives = 59/188 (31%), Gaps = 28/188 (14%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDIS-------PEGKVPVVKLDGKWVADSDVIVG 78 + L + Y V + + + P +VP++++ +A S IV Sbjct: 30 IRLIFAYLGIEYTDKRFGV-NGDAFVEFKNFKKEKDTPFEQVPILQIGDLILAQSQAIVR 88 Query: 79 LLEEKY-----PEPSLKTPPEFASVGSKIFGAFVTF-LKSKDANDGSEKALVDELEALEN 132 L +KY E + I F L ++ + L E Sbjct: 89 YLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEK 148 Query: 133 HLK------THSGPFVAGEKITAVDLSLAPKLYHLEVAL-GHYKNWSV-------PESLT 178 LK + + G +T DL++ +E KN+ + +L Sbjct: 149 LLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLP 208 Query: 179 SVRNYAKA 186 +++NY Sbjct: 209 NIKNYITN 216 >2WDU-A nrPDB Length = 211 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 31/178 (17%), Positives = 64/178 (35%), Gaps = 21/178 (11%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL---DGKWV--ADSDVIVGLL 80 + L L + ++ + + P + P G+VP++ + DGK +S I LL Sbjct: 20 IRLLLTCAGVKFEDYQFTMDQWPTIKPTL-PGGRVPLLDVTGPDGKLRRYQESMAIARLL 78 Query: 81 EEKYPEPSLKTPPEFASVG-----SKIFGAFVTFLKSKD-ANDGSEKALVDE-----LEA 129 ++ + ++ T ++ + K + L+ Sbjct: 79 ARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGEKEAKIKEFKENNGPTLLKL 138 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 187 + L++ G VAG +IT DL L L H + + + + + + K+L Sbjct: 139 VSESLESSGGKHVAGNRITLGDLFLFTTLTH---VMETVPGF-LEQKFPKLHEFHKSL 192 >1G7O-A nrPDB Length = 215 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG-KWVADSDVIV 77 CP+ + + K +P + H + ++D + + + +VP+++ D +++ +S IV Sbjct: 8 HCPYCLKARMIFGLKNIPVELH-VLLNDDAETPTRMVGQKQVPILQKDDSRYMPESMDIV 66 Query: 78 GLLEEKYPEPSL 89 +++ +P L Sbjct: 67 HYVDKLDGKPLL 78 >4Q5R-A nrPDB Length = 204 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 35/185 (18%), Positives = 70/185 (37%), Gaps = 26/185 (14%) Query: 25 RVLLTLEEKKLPYKTHLINVSDKPQW--FLDISPEGKVPVVKLDGKWVADSDVIVGLLEE 82 R LL+ EK ++ + + W P GK PV+++DGK S I L + Sbjct: 20 RFLLSYGEK--DFEDYR---FQEGDWPNLKPSMPFGKTPVLEIDGKQTHQSVAISRYLGK 74 Query: 83 KYPEPSLKTPPE--FASVGSKIFGAFVTFLKS--KDANDGSEKALVDEL---------EA 129 ++ S K E + F + + DA++ S++ D L + Sbjct: 75 QF-GLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDPLKKETIPYYTKK 133 Query: 130 LENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFS 189 + +K + G ++A K+T D L +L H + + +++ + + Sbjct: 134 FDEVVKANGG-YLAAGKLTWADFYFVAILDYLN----HMAKEDLVANQPNLKALREKVLG 188 Query: 190 RESFE 194 + + Sbjct: 189 LPAIK 193 >6GCB-A nrPDB Length = 325 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 40/249 (16%), Positives = 82/249 (32%), Gaps = 60/249 (24%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLI----NVSDKPQW-FLDISPEG--------------- 58 CP++ R L+ + K L + + + W F D+SP Sbjct: 55 SCPWATRTLIVRKIKGLE-EIVGVTIVSPLFSAHGWPFGDVSPFPGAEADPFYNAQYVRD 113 Query: 59 -------------KVPVV---KLDGKWVADSDVIVGLLEEKYPEPSLKT-------PPEF 95 VPV+ K + +S I+ + + E P Sbjct: 114 LYLRADPKYEGRFTVPVLWDKKTETVVNNESSEIIRIFNTAFNEFLPADKAAIHLYPEAL 173 Query: 96 ASVGSKIFGAFVTFLKSKD-------ANDGSEKALV---DELEALENHLKTHSGPFVAGE 145 S +I + + E A++ + L+ LE L ++ G+ Sbjct: 174 KSEIDEINEWVYDTVNNGVYKAGFATTQQAYEAAVIPLFESLDRLEKILTGKD--YLVGD 231 Query: 146 KITAVDLSLAPKLYHLEVAL-GHYKN--WSVPESLTSVRNYAKALF-SRESFENTKAKKE 201 ++T D+ L + + A GH+K ++ + ++ + + L+ + +F T Sbjct: 232 QLTEADVRLFVTIIRFDPAYVGHFKCNLRTIRDGYPAIHLWLRKLYWNNSAFSETCKFDH 291 Query: 202 IVVAGWESK 210 I + + K Sbjct: 292 IKASYYAQK 300 >1GSQ-A nrPDB Length = 202 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 33/194 (17%), Positives = 63/194 (32%), Gaps = 27/194 (13%) Query: 26 VLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYP 85 L + ++ ++D P + +PV+ +DG ++ S I L ++ Sbjct: 17 CRFVLAAHGEEFTDRVVEMADWPNLKATMY-SNAMPVLDIDGTKMSQSMCIARHLAREF- 74 Query: 86 EPSLKTPPEFASVGS------KIFGAFVTF-LKSKDANDGSEKALVDELEAL----ENHL 134 KT E V IF V + A + ++ + L E L Sbjct: 75 GLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQQNYEKSCKRLAPFLEGLL 134 Query: 135 KTHSGP--FVAGEKITAVD--LSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKA---L 187 ++ G F G +T D +A LEV L H + + + K Sbjct: 135 VSNGGGDGFFVGNSMTLADLHCYVA-----LEVPLKH--TPELLKDCPKIVALRKRVAEC 187 Query: 188 FSRESFENTKAKKE 201 ++ + ++ Sbjct: 188 PKIAAYLKKRPVRD 201 >2X8H-A nrPDB Length = 598 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLIN-VSDKPQWFLDISPEGK---VPVVKLDGKWVADSD 74 CP+ ++V L E K+ + T ++ +S+ ++ K VP + + GK++ DS Sbjct: 27 TCPYCKKVKDVLAEAKIKHATIELDQLSNGSAIQKCLASFSKIETVPQMFVRGKFIGDSQ 86 Query: 75 VIVGL 79 ++ Sbjct: 87 TVLKY 91 >3IR4-A nrPDB Length = 218 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 65/185 (35%), Gaps = 42/185 (22%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGK-VPVVKLDG-KWVADSDVI 76 CPF + + K +P + ++ + + + K VP+++ D +++ +S I Sbjct: 11 HCPFCVKARMIFGLKNIPVELNV--LQNDDEATPTRMIGQKMVPILQKDDSRYLPESMDI 68 Query: 77 VGLLEEKYPEPSL------------------KTPPEFASVGSKIFGAFVT------FLKS 112 V ++ +P L F F T F++ Sbjct: 69 VHYVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLLPRFAKSAFDEFSTPAARQYFIRK 128 Query: 113 KDAND-----------GSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHL 161 K+A+ G K + D+L L+ + P +++ D+ L P L +L Sbjct: 129 KEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQ---PNAVNGELSEDDIHLFPLLRNL 185 Query: 162 EVALG 166 + G Sbjct: 186 TLVAG 190 >5LKB-A nrPDB Length = 378 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 30/228 (13%), Positives = 70/228 (30%), Gaps = 47/228 (20%) Query: 23 SQRVLLTLEEKKLPYKTHLI-NVSDKPQWFLDISPEGKVPVV---KLDGKWVADSDVIV- 77 SQR + + Y I ++ K S VPV+ + +S I+ Sbjct: 123 SQR-FMVDATNEPHYGYKRISDLYYKSD--PQYSARFTVPVLWDLETQTIVNNESSEIIR 179 Query: 78 --------GLLEEKYPEPSLKTPPEFASVGSK-------IFGAFVT--FLKSKDANDGSE 120 +++ + + L + I F + + + Sbjct: 180 ILNSSAFDEFVDDDHKKTDLVPAQLKTQIDDFNSWVYDSINNGVYKTGFAEKAEVYESEV 239 Query: 121 KALVDELEALENHLKTHSGP-----------------FVAGEKITAVDLSLAPKLYHLEV 163 + + L+ +E L F G+++T D+ L + + Sbjct: 240 NNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFDP 299 Query: 164 AL-GHYK-NW-SVPESLTSVRNYAKALF-SRESFENTKAKKEIVVAGW 207 H+K N+ S+ + + + L+ + ++F T + + + Sbjct: 300 VYVQHFKCNFTSIRAGYPFIHLWVRNLYWNYDAFRYT-TDFDHIKLHY 346 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 7/17 (41%), Positives = 10/17 (58%) Query: 20 CPFSQRVLLTLEEKKLP 36 CP++ R L+T K L Sbjct: 46 CPWAHRTLITRALKGLT 62 >4LA1-A nrPDB Length = 602 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLIN-VSDKPQWFLDISPEGK---VPVVKLDGKWVADSD 74 CPF +++ L E K+ + T ++ +S+ +S K VP + + GK++ DS Sbjct: 33 TCPFCKKLKDVLAEAKIKHATIELDQLSNGSVIQKALSNFSKIETVPQMFVRGKFIGDSK 92 Query: 75 VIVGL 79 ++ Sbjct: 93 AVLNY 97 >1M0U-A nrPDB Length = 249 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 48/135 (35%), Gaps = 20/135 (14%) Query: 36 PYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEF 95 Y+ + D+ P G++PV+++DGK V S + L L + Sbjct: 74 EYEDVRV-TRDEWPALKPTMPMGQMPVLEVDGKRVHQSISMARFL---AKTVGLCGATPW 129 Query: 96 ASVGSKIFGAFVTFLKSK------DANDGSEKALVDELEA---------LENHLKTHSGP 140 + I + + K + D ++ + L A LE +K + G Sbjct: 130 EDLQIDIVVDTINDFRLKIAVVSYEPEDEIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGH 189 Query: 141 FVAGEKITAVDLSLA 155 G K+T D+ A Sbjct: 190 LALG-KLTWADVYFA 203 >4USS-A nrPDB Length = 325 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 35/90 (38%), Gaps = 4/90 (4%) Query: 109 FLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALG-H 167 F + + + + L + L+ E L ++ G ++ D+ L L + H Sbjct: 196 FARKQGPYEEAAIQLYEALDKCEEILGRQ--RYICGNTLSEADIKLFVTLIRFDEVYAVH 253 Query: 168 YK-NWSVPESLTSVRNYAKALFSRESFENT 196 +K N + ++ NY K +F +T Sbjct: 254 FKCNKKLLRDYPNMFNYTKDIFQIPGMSST 283 >5AN1-A nrPDB Length = 219 Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 32/197 (16%), Positives = 65/197 (32%), Gaps = 24/197 (12%) Query: 23 SQRVLLTLEEKKLPYKTHLINV-----SDKPQWFLDISPEG----KVPVVKLDGKWVADS 73 Q + L L ++ V DK +W G +P + S Sbjct: 14 CQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYYIDGDVKITQS 73 Query: 74 DVIVGLLEEKY------PEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSEKALVDEL 127 I+ L K+ PE ++T + F + + D +L +L Sbjct: 74 KAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQKDAYTASLPAKL 133 Query: 128 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYK-NWSVPESLTSVRNYAKA 186 + L + P+ AG+K+T +D E+ H + + + +++ + K Sbjct: 134 RQYSDFLGSR--PWFAGDKLTYID------FLAYEIFDQHLSLDRTCLDGFKNLQAFQKR 185 Query: 187 LFSRESFENTKAKKEIV 203 E+ + A + + Sbjct: 186 FEDLEAIKKYMASPKFL 202 >4LMV-A nrPDB Length = 252 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 38/107 (35%), Gaps = 19/107 (17%) Query: 15 DVLGDCPFS---QRVLLTLEEKKLPYKTHLINVSDKPQWFLDI--SPEGK---------V 60 D L P+S ++ L K + YKT + D + P GK V Sbjct: 13 DTLKQSPWSPNTWKIRYALNIKGIKYKTEWVEYPDIEDVVKKLGGKPTGKKPDGRDHYTV 72 Query: 61 PVV-KLDGKWVADSDV-IVGLLEEKYPEPSLKTP---PEFASVGSKI 102 PV+ + K V + + I L++ YP+ P F + Sbjct: 73 PVIYDPNTKTVVEDGIKIAKYLDDAYPDTPRLFPAGTDAFQAAFDDF 119 >5F8B-A nrPDB Length = 244 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 24/183 (13%), Positives = 63/183 (34%), Gaps = 26/183 (14%) Query: 29 TLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKW-VADSDVIVGLLEEKYPEP 87 + L + L IS GKVP + + + + I + + + Sbjct: 22 VAKANGLDLDIRETP---RTPDHLSISKLGKVPAFQGADSFKLFECMAIALYITSQNEQT 78 Query: 88 SL--KTPPEFASVGS--KIFGAFVTFLKSK-------------DANDGSEKALVDELEAL 130 +L K E+A + F + L ++ D + ++ + Sbjct: 79 TLLGKDKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGVIPYDRDQVEFFANMTQRSVDVV 138 Query: 131 ENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFSR 190 E +L+ + F+ G++++ DL A ++ + + + + +V + + + + Sbjct: 139 EEYLQDRT--FLVGDQLSLADLFCA---GNISLGFQFFYGKAWRQQNPNVSRWYEMVCHQ 193 Query: 191 ESF 193 + Sbjct: 194 PIY 196 >2PBJ-A nrPDB Length = 290 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 19/127 (14%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLD----GKWVADSD 74 CPF +V L+ LPY+ +N + + + S KVP++ + + DS Sbjct: 22 TCPFCSKVRAFLDFHALPYQVVEVNPVLRAE--IKFSSYRKVPILVAQEGESSQQLNDSS 79 Query: 75 VIV----------GLLEEKYP-EPSLKTPPEFASVGSKIFGAFVTFLKSKDAND--GSEK 121 VI+ LEE P++K + ++ + L K+A ++ Sbjct: 80 VIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGNKYWLMLNEKEAQQVYSGKE 139 Query: 122 ALVDELE 128 A +E++ Sbjct: 140 ARTEEMK 146 >5FWG-A nrPDB Length = 217 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 66/202 (32%), Gaps = 35/202 (17%) Query: 24 QRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEG----KVPVVKLDGKWVADSD 74 + L LE Y+ + D P QW + G +P + + + S+ Sbjct: 14 HPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSN 73 Query: 75 VIVGLLEEKYPEPSLKTPPEFASVGSKIFG--------AFVTFLKSKD---ANDGSEKAL 123 I+ L K+ L E + + I + + D K + Sbjct: 74 AIMRYLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTI 130 Query: 124 VDELEALENHLKTHSGPFVAGEKITAVD---LSLAPKLYHLEV----ALGHYKNWSVP-E 175 ++++ L P+ AG+K+T VD + + + E A + K++ E Sbjct: 131 PEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFE 188 Query: 176 SLTSVRNYAK--ALFSRESFEN 195 L + Y K S F Sbjct: 189 GLKKISAYMKSSRYLSTPIFSK 210 >6GC9-A nrPDB Length = 327 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 31/235 (13%), Positives = 76/235 (32%), Gaps = 60/235 (25%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLI-------------------------NVSDKPQ----W 50 CP++ R L+ + K L + + + + Sbjct: 57 CPWATRTLIVRKIKGLE-EFIDVSVVSPRMGAHGWPFANVDAFPGADADPLFGAEHVKDL 115 Query: 51 FLDISP----EGKVPVV---KLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIF 103 ++ ++P VP++ K +S I+ + + + + Sbjct: 116 YMRVNPDYEGRFTVPILWDKKTSAIVNNESSEIIRMFNTAFNDQLPSDKAAIDLYPEALR 175 Query: 104 GAF-----------------VTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEK 146 G F S+ A + + L + L+ LE L ++ G++ Sbjct: 176 GEIDGINEWVYDTVNNGVYKSGFATSQKAYEAAVVPLFESLDRLEKILTGKD--YLVGDQ 233 Query: 147 ITAVDLSLAPKLYHLEVAL-GHYKN--WSVPESLTSVRNYAKALF-SRESFENTK 197 +T D+ L + + GH+K ++ + ++ + + L+ + +F +T Sbjct: 234 LTEADIRLFVTIVRFDPVYVGHFKCNIRTIRDGYPAIDLWMRKLYWNNSAFSSTC 288 >1B4P-A nrPDB Length = 217 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 40/216 (18%), Positives = 69/216 (31%), Gaps = 41/216 (18%) Query: 24 QRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEG----KVPVVKLDGKWVADSD 74 + L LE Y+ + D P QW + G +P + + + S+ Sbjct: 14 HPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSN 73 Query: 75 VIVGLLE-------EKYPEPSLKTPPEFASVGSKIFGAFVTFL-KSKDANDGSEKALVDE 126 I+ L E E E ++ +++ A V + + + L ++ Sbjct: 74 AIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFERKKPEYLEGLPEK 133 Query: 127 LEALENHLKTHSGPFVAGEKITAVDLSLA----------PKLYHLEVALGHYKNWSVPES 176 ++ L P+ AG KIT VD + PK L + E Sbjct: 134 MKLYSEFLGKQ--PWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNLKDFVARF--EG 189 Query: 177 LTSVRNYAK--ALFSRESFENTKAKKEIVVAGWESK 210 L + +Y K S+ F +A W K Sbjct: 190 LKKISDYMKSGRFLSKPIFAK--------MAFWNPK 217 >1HNA-A nrPDB Length = 217 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 44/201 (21%), Positives = 69/201 (34%), Gaps = 31/201 (15%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEG----KVPVVKLDGKWVADS 73 + + L LE Y+ + D P QW + G +P + + S Sbjct: 13 AHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQS 72 Query: 74 DVIVGLLEEKYPEPSLKTPPEFASVGSKI----FGAFVTFLKSKDANDGSEKALVDELEA 129 + I+ + K+ +L E + I F L + EK + L+A Sbjct: 73 NAILRYIARKH---NLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQA 129 Query: 130 LENHLKTHSG-----PFVAGEKITAVDLSLAPKLYHLEV-------ALGHYKNW-SVPES 176 L LK +S P+ G+KIT VD L +V A + K++ S E Sbjct: 130 LPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEG 189 Query: 177 LTSVRNYAK--ALFSRESFEN 195 L + Y K R F Sbjct: 190 LEKISAYMKSSRFLPRPVFTK 210 >3GRX-A nrPDB Length = 82 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLIN-VSDKPQWFLDISPEGKVPVVKLDGKWV 70 CP+S R L K + ++ I+ + K + + S VP + +D + + Sbjct: 10 TCPYSHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFIDAQHI 62 >1TU7-A nrPDB Length = 208 Score = 36.9 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 29/145 (20%), Positives = 48/145 (33%), Gaps = 22/145 (15%) Query: 35 LPYKTHLINVSDKPQWFLDISP---EGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKT 91 + I+ F I G++P + + + S I+ L KY +L Sbjct: 22 VDQDIKFIDDRIAKDDFSSIKSQFQFGQLPCLYDGDQQIVQSGAILRHLARKY---NLNG 78 Query: 92 PPEFASVGSKIFGAFVTFLKSK-----------DANDGSEKALVDELEALENHLKTHS-- 138 E + +F V L K + + + L EL E L T Sbjct: 79 ENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEKDPYIKSILPGELAKFEKLLATRGNG 138 Query: 139 GPFVAGEKITAVDLSLAPKLYHLEV 163 + G+KI+ D +L L+V Sbjct: 139 RNLILGDKISYADYAL---FEELDV 160 >4BVY-B nrPDB Length = 186 Score = 35.7 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 53/130 (40%), Gaps = 11/130 (8%) Query: 59 KVPVVKLDG--KWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAN 116 ++PV++ + + + L+++ E L + E + I ++ + ++ Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKA----IVQQWLEYRVTQVDG 96 Query: 117 DGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVAL---GHYKNWSV 173 S+ + L+ L ++L+ ++ G T D+ L L+ V L K +V Sbjct: 97 HSSKNDIHTLLKDLNSYLEDK--VYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNV 154 Query: 174 PESLTSVRNY 183 + +++Y Sbjct: 155 SRWFSHIQHY 164 >2DC5-A nrPDB Length = 231 Score = 35.7 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 65/203 (32%), Gaps = 35/203 (17%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEG----KVPVVKLDGKWVADS 73 + + L LE Y+ + D P QW + G +P + + S Sbjct: 21 AHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQS 80 Query: 74 DVIVGLLEEKYPEPSLKTPPEFASVGSKIFG-------AFVTFLKSKDANDGSEKALVDE 126 + I+ L K+ +L E + I + L + + +++ Sbjct: 81 NAILRYLGRKH---NLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPGYLEQ 137 Query: 127 L----EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEV-------ALGHYKNWSVP- 174 L L P+ AG+KIT VD L +V A + K++ Sbjct: 138 LPGMMRLYSEFLG--KRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPNLKDFIARF 195 Query: 175 ESLTSVRNYAK--ALFSRESFEN 195 E L + +Y K R F Sbjct: 196 EGLKKISDYMKTSRFLPRPMFTK 218 >2KLX-A nrPDB Length = 89 Score = 35.7 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 20/49 (40%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG 67 +CP+ +R L++K + Y + S + + + P + + Sbjct: 15 NCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFPQIFIGD 63 >3QMX-A nrPDB Length = 99 Score = 34.6 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLIN 43 CPF R L L+ K + ++ + I+ Sbjct: 25 TCPFCMRALALLKRKGVEFQEYCID 49 >1NM3-A nrPDB Length = 241 Score = 34.2 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 24/60 (40%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGL 79 CPF + L +K L ++ ++ +S VP V + GK + SD + Sbjct: 180 CPFCAKAKQLLHDKGLSFEEIILGHDATIVSVRAVSGRTTVPQVFIGGKHIGGSDDLEKY 239 >4GTU-A nrPDB Length = 217 Score = 33.8 bits (76), Expect = 0.057, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 51/147 (34%), Gaps = 21/147 (14%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEG----KVPVVKLDGKWVADS 73 + + L LE Y+ + D P QW + G +P + + S Sbjct: 13 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 72 Query: 74 DVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDAN-------DGSEKALVDE 126 + I+ + K+ +L E + I + ++ A + + ++E Sbjct: 73 NAILCYIARKH---NLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLKPEYLEE 129 Query: 127 LEALENHLKT--HSGPFVAGEKITAVD 151 L + H P+ G+KIT VD Sbjct: 130 LPTMMQHFSQFLGKRPWFVGDKITFVD 156 >1XWK-A nrPDB Length = 218 Score = 33.4 bits (75), Expect = 0.064, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 66/200 (33%), Gaps = 29/200 (14%) Query: 23 SQRVLLTLEEKKLPYKTHLINVSDKP-----QWFLDISPEG----KVPVVKLDGKWVADS 73 + + L LE Y+ + D P QW + G +P + + S Sbjct: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 Query: 74 DVIVGLLE-------EKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSE-KALVD 125 + I+ + E E E ++ + + + + + + L + Sbjct: 74 NAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPE 133 Query: 126 ELEALENHLKTHSGPFVAGEKITAVDLSL--APKLYHLEV-----ALGHYKNW-SVPESL 177 +L+ L P+ AG KIT VD + L+ + A + K++ S E L Sbjct: 134 KLKLYSEFLG--KRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGL 191 Query: 178 TSVRNYAK--ALFSRESFEN 195 + Y K R F Sbjct: 192 EKISAYMKSSRFLPRPVFSK 211 >1FHE-A nrPDB Length = 217 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 31/185 (16%), Positives = 60/185 (32%), Gaps = 26/185 (14%) Query: 46 DKPQWFLDISPEG----KVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSK 101 D+ +W + G +P D + S I+ + +K L T PE + S Sbjct: 36 DREKWMSEKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADK--HGMLGTTPEERARISM 93 Query: 102 I----------FGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVD 151 I FG K ++ + K L L+ + L ++ G ++ VD Sbjct: 94 IEGAAMDLRIGFGRVCYNPKFEEVKEEYVKELPKTLKMWSDFLGDRH--YLTGSSVSHVD 151 Query: 152 LSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIV---VAGWE 208 L L + H + ++ + + + + K + + GW Sbjct: 152 FMLYETLDSIRYLAPHCLD-----EFPKLKEFKSRIEALPKIKAYMESKRFIKWPLNGWA 206 Query: 209 SKVNA 213 + A Sbjct: 207 ASFGA 211 >1Z7R-A nrPDB Length = 117 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 7/84 (8%) Query: 2 ALDICVKVAVGAPDVLGD---CPFSQRVLLTLEEKKLPYKTHLIN-VSDKPQWFLDIS-- 55 AL ++A AP V+ C + RV L + YK ++ +SD Q ++ Sbjct: 10 ALKKAKELASSAPVVVFSKTYCGYCNRVKQLLTQVGASYKVVELDELSDGSQLQSALAHW 69 Query: 56 -PEGKVPVVKLDGKWVADSDVIVG 78 G VP V + GK + D +V Sbjct: 70 TGRGTVPNVFIGGKQIGGCDTVVE 93 >6JR6-A nrPDB Length = 838 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 17/42 (40%), Gaps = 3/42 (7%) Query: 46 DKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEK--YP 85 QW +P +PV G + ++ ++EK YP Sbjct: 664 KGEQWITVDAPLNTIPVFVKKGSIIPQ-MPVMQYIDEKKVYP 704 >3IC4-A nrPDB Length = 92 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 12/77 (15%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFL------DISPEGKVPVVKLDGKWV 70 L CP +R L L+ + + ++ I+ + + IS VPVV K V Sbjct: 19 LSTCPHCKRTLEFLKREGVDFEVIWIDKLEGEERKKVIEKVHSISGSYSVPVVVKGDKHV 78 Query: 71 ADSDVIVGLLEEKYPEP 87 +G EEK E Sbjct: 79 ------LGYNEEKLKEL 89 >5CAX-A nrPDB Length = 101 Score = 31.9 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 27/69 (39%), Gaps = 7/69 (10%) Query: 17 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKV----PVVKLDGKWVAD 72 L C + ++ L + + ++ +++ ++ + + +V P V + D Sbjct: 27 LSTCVWCKKTKKLLTDLGVDFEYVFVDLLEEEE---KSNAIKQVSRFNPSVSFPTTILND 83 Query: 73 SDVIVGLLE 81 IVG E Sbjct: 84 EKAIVGFKE 92 >2MZC-A nrPDB Length = 92 Score = 31.5 bits (70), Expect = 0.27, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 28/75 (37%), Gaps = 5/75 (6%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQW---FLDISPEGKVPVVKLDGKWVADSDVI 76 CP+ R L K + I+ S P+ + S P + + V SD + Sbjct: 16 CPYCARAKALLARKGAEFN--EIDASATPELRAEMQERSGRNTFPQIFIGSVHVGGSDDL 73 Query: 77 VGLLEEKYPEPSLKT 91 L +E + LKT Sbjct: 74 YALEDEGKLDSLLKT 88 >5W1J-A nrPDB Length = 584 Score = 31.5 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 17/110 (15%), Positives = 46/110 (41%), Gaps = 5/110 (4%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDI----SPEGKVPVVKLDGKWVADSDV 75 CP+ ++V+ K+P+ +++ + + + VP V G+++ D Sbjct: 25 CPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFIGGCDD 84 Query: 76 IVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSEKALVD 125 ++ + ++ + + + ++ V + K A G++ AL+D Sbjct: 85 VMAIDDDTIVKKANEMKYDYDMVIIGGGSGGLALAKES-AKSGAKVALLD 133 >2WRT-A nrPDB Length = 218 Score = 31.5 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 57/165 (34%), Gaps = 30/165 (18%) Query: 46 DKPQWFLDISPEG----KVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSK 101 D+ +W D G +P D + S I+ + +K L + PE + S Sbjct: 37 DREKWLGDKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADK--HGMLGSTPEERARISM 94 Query: 102 IFGAFVTFL----------KSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVD 151 I GA + K ++ K L L+ N L ++ G ++ VD Sbjct: 95 IEGAAMDLRMGFVRVCYNPKFEEVKGDYLKELPTTLKMWSNFLGDRH--YLTGSSVSHVD 152 Query: 152 LS----------LAPKLYHLEVALGHYKNWSVPESLTSVRNYAKA 186 LAP+ L +K S E L ++ Y ++ Sbjct: 153 FMVYEALDCIRYLAPQCLEDFPKLKEFK--SRIEDLPKIKAYMES 195 >2X75-A nrPDB Length = 431 Score = 31.1 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV--VKLDGKWVADSDVIVGL 79 FSQRVLL L K + DK Q IS E K P + + + S + Sbjct: 353 FSQRVLLALINKGM----VREEAYDKVQPKAMISWETKTPFRELIEQDESIT-SVLTKEE 407 Query: 80 LEEKY-PEPSL 89 L+E + P+ L Sbjct: 408 LDECFDPKHHL 418 >3A58-B nrPDB Length = 188 Score = 30.0 bits (66), Expect = 0.74, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 7/60 (11%) Query: 22 FSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 F Q V + L +++ + PQ + EG+ PV +G+ VAD G E Sbjct: 111 FCQGVPIILV--GCK-----VDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYE 163 >3H4X-A nrPDB Length = 339 Score = 30.0 bits (66), Expect = 0.87, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 31/97 (31%), Gaps = 10/97 (10%) Query: 98 VGSKIFGAFVTFLKSKDA-----NDGSEKALVDELEALENHLKTHSGPFVAGEKIT---- 148 G +F ++ K+ D + +L A ++ + P V G Sbjct: 186 AGKFLFELIPGTVEEKNPFDKLWTDVEYAGHLKDLAAQGKLAQSTAFPAVHGAAPGDPRE 245 Query: 149 -AVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYA 184 D +L P + Y N S+ S R+Y Sbjct: 246 RYADPALRPWFVVFDGDAATYLNGSIDTSWYDTRHYL 282 >5Y4U-A nrPDB Length = 115 Score = 30.0 bits (66), Expect = 0.90, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKP--QWFLDISPEGKVPVVKLDGKWVADSDVIV 77 C FS++++ L E ++ + I + D+ Q S P + ++G++ D+I Sbjct: 33 CGFSRQLVGILREHQVRFGFFDI-LRDESVRQNLKKFSEWPTFPQLYINGEFQGGLDIIK 91 Query: 78 GLLEE 82 LEE Sbjct: 92 ESLEE 96 >3UIW-A nrPDB Length = 154 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 21/56 (37%), Gaps = 4/56 (7%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINV----SDKPQWFLDISPEGKVPVVKLDGKWV 70 CP+ + E YK ++ + +++ VP V ++G+ + Sbjct: 56 TCPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCI 111 >3C1S-A nrPDB Length = 118 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 28/59 (47%), Gaps = 8/59 (13%) Query: 20 CPFSQRVLLTLEEK-KLPYKTHLI----NVSDKPQW---FLDISPEGKVPVVKLDGKWV 70 CP+ L TL EK K+P L+ ++ + +I+ + VP + ++GK + Sbjct: 35 CPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHI 93 >2JAD-A nrPDB Length = 364 Score = 28.0 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 8/59 (13%) Query: 20 CPFSQRVLLTLEEK-KLPYKTHLI----NVSDKPQW---FLDISPEGKVPVVKLDGKWV 70 CP+S L TL EK K+P L+ ++ + +I+ + VP + ++GK + Sbjct: 273 CPYSHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHI 331 >3DAD-A nrPDB Length = 339 Score = 28.0 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 30/84 (35%), Gaps = 4/84 (4%) Query: 66 DGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSEKALVD 125 DG+ V+ V V LE+ P S P + + GA L + L Sbjct: 9 DGEPVSVVTVRVQYLEDTDPFASANFPEPRRAPTCSLDGA----LPLGAQIPAVHRLLGA 64 Query: 126 ELEALENHLKTHSGPFVAGEKITA 149 L+ ++ L+ + +++ Sbjct: 65 PLKLEDSALQVSPSGYYLDTELSL 88 >3CG1-A nrPDB Length = 296 Score = 27.7 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 9/66 (13%), Positives = 19/66 (28%), Gaps = 9/66 (13%) Query: 145 EKITAVDLSLAPKLYHLEV--ALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEI 202 + I D +L P+L + + + T Y + + + K Sbjct: 62 DVIGVADYTLIPQLLIPNYTDFYVLFATNEIVIAFTDKSRYVEEM-------KSNPDKWY 114 Query: 203 VVAGWE 208 + E Sbjct: 115 EILARE 120 >2ATX-A nrPDB Length = 194 Score = 27.7 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 17/42 (40%) Query: 40 HLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLE 81 I++ D P+ ++ + P+ G+ +A +E Sbjct: 130 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVE 171 >5DXT-A nrPDB Length = 962 Score = 27.7 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 22/51 (43%) Query: 35 LPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYP 85 +P + + K + L S + K+ V++ GK++ EKYP Sbjct: 110 VPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYP 160 >4TR1-A nrPDB Length = 92 Score = 27.7 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 20 CPFSQRVLLTLEEKKLPYKTHLINVSDKP-QWFLDISPEGKVPVVKLDGKWVADSDVI 76 CP+S++ + L K + +K + K + + + VP V +D +++ D I Sbjct: 12 CPYSKKAVSLLSSKGVDFKEVDVTHDSKAFEDVMAKTGWDTVPQVFVDEEFLGGCDDI 69 >1H75-A nrPDB Length = 81 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 7/49 (14%), Positives = 16/49 (32%) Query: 19 DCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDG 67 DC +E + ++ ++ + L ++PVV Sbjct: 10 DCVQCHATKRAMENRGFDFEMINVDRVPEAAEALRAQGFRQLPVVIAGD 58 >3AII-A nrPDB Length = 553 Score = 27.3 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 7/99 (7%) Query: 97 SVGSKIFGAFVTFLKSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAP 156 +V + G L+ KD EK E L HL F+ ++ D++L+ Sbjct: 279 AVDDHLLGVTHV-LRGKDHLANREKQ-----EYLYRHLGWEPPEFIHYGRLKMDDVALST 332 Query: 157 KLYHLEVALGHYKNWSVPESLTSVRNYAKALFSRESFEN 195 + G Y W P L ++R A+ E+ Sbjct: 333 SGAREGILRGEYSGWDDPR-LGTLRAIARRGIRPEAIRK 370 >3RE1-A nrPDB Length = 269 Score = 27.3 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 21/49 (42%) Query: 75 VIVGLLEEKYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDANDGSEKAL 123 + + L++E +P+P ++ S +I + + D SE L Sbjct: 80 LAIELIDEVWPQPPMQPWFSVGSATGQILLDYGLDASWPEQGDDSEALL 128 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.140 0.374 Lambda K H 0.267 0.0438 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,486,196 Number of Sequences: 36641 Number of extensions: 349542 Number of successful extensions: 1204 Number of sequences better than 10.0: 161 Number of HSP's better than 10.0 without gapping: 164 Number of HSP's successfully gapped in prelim test: 90 Number of HSP's that attempted gapping in prelim test: 807 Number of HSP's gapped (non-prelim): 272 length of query: 213 length of database: 10,336,785 effective HSP length: 93 effective length of query: 120 effective length of database: 6,929,172 effective search space: 831500640 effective search space used: 831500640 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 57 (26.5 bits)