BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9ERD7 (450 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5IJ0-B nrPDB 899 0.0 6GJ4-B nrPDB 833 0.0 6E88-B nrPDB 795 0.0 5UCY-B nrPDB 780 0.0 5MLV-I nrPDB 697 0.0 4FFB-B nrPDB 696 0.0 6E88-A nrPDB 369 e-102 5UBQ-C nrPDB 367 e-102 5MLV-E nrPDB 362 e-100 2XRP-B nrPDB 356 1e-98 5W3H-A nrPDB 353 9e-98 5ND4-A nrPDB 341 3e-94 2BTQ-B nrPDB 307 6e-84 1Z5V-A nrPDB 295 3e-80 2BTQ-A nrPDB 288 2e-78 5FM1-C nrPDB 208 3e-54 3ZID-A nrPDB 33 0.18 4XCQ-A nrPDB 32 0.45 3V3T-A nrPDB 30 2.0 5CKV-A nrPDB 30 2.6 5HUD-A nrPDB 29 4.1 2OZX-A nrPDB 29 4.1 5IM3-A nrPDB 29 4.7 2HW4-A nrPDB 29 5.1 3R44-A nrPDB 28 7.9 >5IJ0-B nrPDB Length = 426 Score = 899 bits (2324), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/426 (100%), Positives = 426/426 (100%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV Sbjct: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV Sbjct: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL Sbjct: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM Sbjct: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG Sbjct: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQ 426 EYQQYQ Sbjct: 421 EYQQYQ 426 >6GJ4-B nrPDB Length = 445 Score = 833 bits (2151), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/430 (93%), Positives = 420/430 (97%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDP+G+Y GDSDLQLERI+VYYNEA+ +KYV Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRAILVDLEPGTMDSVRSG FG +FRPDNF+FGQSGAGNNWAKGHYTEGAELVDSVLDVV Sbjct: 61 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKE E+CDCLQGFQLTHSLGGGTGSGMGTLLISK+REEYPDRIMNTFSV+PSPKVSDTVV Sbjct: 121 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVENTDETYCIDNEALYDICFRTLKL TPTYGDLNHLVSATMSGVTT L Sbjct: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLT+RGSQQYRALTVPELTQQMFD+KNMM Sbjct: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AACDPRHGRYLTVA +FRGRMSMKEVDEQML +Q+KNSSYFVEWIPNNVK AVCDIPPRG Sbjct: 301 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKMS+TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQDATA 430 EYQQYQDATA Sbjct: 421 EYQQYQDATA 430 >6E88-B nrPDB Length = 426 Score = 795 bits (2052), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/426 (89%), Positives = 407/426 (95%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVH+QAGQCGNQIG+KFWEVISDEHGI P G + G++DLQLERI VYYNEA++ KYV Sbjct: 1 MREIVHVQAGQCGNQIGSKFWEVISDEHGIQPDGTFKGETDLQLERIDVYYNEANNGKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRA+LVDLEPGTMDSVRSG FG LFRPDNF+FGQSGAGNNWAKGHYTEGAELVD+VLDV+ Sbjct: 61 PRAVLVDLEPGTMDSVRSGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVLDVI 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKE E CDCLQGFQLTHSLGGGTGSGMGTLLISK+REEYPDRIM++FSVVPSPKVSDTVV Sbjct: 121 RKEAEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMSSFSVVPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVENTDETYCIDNEALYDIC+RTLKL PTYGDLNHLVS TMSGVTT L Sbjct: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICYRTLKLTNPTYGDLNHLVSLTMSGVTTCL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPL+A+G+Q YRALTV ELTQQMFDAKNMM Sbjct: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLSAKGTQAYRALTVAELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AACDPRHGRYLTVA +FRGRMSM+EVDEQML +Q+KNSSYFVEWIPNNVK AVCDIPPRG Sbjct: 301 AACDPRHGRYLTVAAMFRGRMSMREVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKM++TF+GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDL+S Sbjct: 361 LKMAATFVGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLIS 420 Query: 421 EYQQYQ 426 EYQQYQ Sbjct: 421 EYQQYQ 426 >5UCY-B nrPDB Length = 429 Score = 780 bits (2013), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/429 (87%), Positives = 402/429 (93%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQ GQCGNQIGAKFWEVISDEHGIDP+G Y GDSDLQLERI+VYYNEA+ +YV Sbjct: 1 MREIVHIQGGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGRYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRAIL+DLEPGTMDSVR+G FG LFRPDNF+FGQ+GAGNNWAKGHYTEGAEL+DSVLDVV Sbjct: 61 PRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKE E CDCLQGFQ+THSLGGGTGSGMGTLLISKVREEYPDRIM TFSVVPSPKVSDTVV Sbjct: 121 RKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVVPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVEN DE IDNEALYDICFRTLKL TPTYGDLNHLVSA MSGVT L Sbjct: 181 EPYNATLSVHQLVENADECMVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLN+DLRKLAVN++PFPRLHFFM GFAPLT+RGSQQYRALTVPELTQQMFDAKNMM Sbjct: 241 RFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 A DPRHGRYLT + +FRGRMS KEVDEQML +Q+KNSSYFVEWIPNN+K ++CDIPP+G Sbjct: 301 CAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSICDIPPKG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKM+ TF+GNSTAIQE+FKR++EQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMAVTFVGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQDAT 429 EYQQYQDAT Sbjct: 421 EYQQYQDAT 429 >5MLV-I nrPDB Length = 448 Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/428 (77%), Positives = 383/428 (89%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQAGQCGNQ+GA FW I+DEHG+D +G Y G S+ Q ER++VY+NEA+ KYV Sbjct: 1 MREIVHIQAGQCGNQVGAAFWSTIADEHGLDSAGIYHGTSEAQHERLNVYFNEAAGGKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRA+LVDLEPGTMD+V+SG FG+LFRPDN I+GQSGAGN WAKGHYTEGAEL D+VLDVV Sbjct: 61 PRAVLVDLEPGTMDAVKSGKFGNLFRPDNIIYGQSGAGNIWAKGHYTEGAELADAVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 R+E E CD LQGFQLTHSLGGGTGSGMGTLL+SK+REEYPDR+M TFSV P+PK SDTVV Sbjct: 121 RREAEACDALQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRMMATFSVAPAPKSSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVEN+DET+CIDNEAL I TLK+ +P+Y DLNHLVSA M+GVTTS Sbjct: 181 EPYNATLSMHQLVENSDETFCIDNEALSSIFANTLKIKSPSYDDLNHLVSAVMAGVTTSF 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPG+LN+DLRKLAVNMVPFPRLHFFM GFAPL A GS ++A++VPELTQQMFDA NMM Sbjct: 241 RFPGELNSDLRKLAVNMVPFPRLHFFMVGFAPLAAIGSSSFQAVSVPELTQQMFDANNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 A DPRHGRYLTVA +FRG++SMKEVDEQ+ ++Q+KNS+YFVEWIP+NV AVC +PP+ Sbjct: 301 VAADPRHGRYLTVAALFRGKVSMKEVDEQIRSVQTKNSAYFVEWIPDNVLKAVCSVPPKD 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKMS+TFIGNST+IQE+F+R+ +QF+AMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMSATFIGNSTSIQEIFRRLGDQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQDA 428 EYQQYQ+A Sbjct: 421 EYQQYQEA 428 >4FFB-B nrPDB Length = 463 Score = 696 bits (1796), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/441 (75%), Positives = 393/441 (89%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREI+HI GQCGNQIGA FWE I EHG+D +G Y G D+Q ER++VY+NEASS K+V Sbjct: 1 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PR+I VDLEPGT+D+VR+ A G+LFRPDN+IFGQS AGN WAKGHYTEGAELVDSV+DV+ Sbjct: 61 PRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVI 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 R+E E CD LQGFQ+THSLGGGTGSGMGTLLISK+REE+PDR+M TFSV+PSPK SDT V Sbjct: 121 RREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKRSDTRV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVE++DET+CIDNEALYDIC RTLKL P+YGDLN+LVS+ MSGVTTSL Sbjct: 181 EPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 R+PGQLN+DLRKLAVN+VPFPRLHFFM G+APLTA GSQ +R+LTVPELTQQMFDAKNMM Sbjct: 241 RYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AA DPR+GRYLTVA FRG++S+KEV+++M +QSKNS YFVEWIPNNV+ AVC + P+G Sbjct: 301 AAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 L M++TFI NST+IQELFKR+ +QF+AMF+RKAFLHWYT EGMDE+EF+EAESNMNDLVS Sbjct: 361 LDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVS 420 Query: 421 EYQQYQDATAEEEGEMYEDDD 441 EYQQYQ+AT E++ E+ E+ D Sbjct: 421 EYQQYQEATVEDDEEVDENGD 441 >6E88-A nrPDB Length = 434 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 179/432 (41%), Positives = 270/432 (62%), Gaps = 8/432 (1%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MRE++ I GQ G QIG WE+ EHGI P G S + E + ++++ S +YV Sbjct: 1 MREVISIHVGQAGVQIGNACWELYCLEHGIQPDGTMPTQSTNEGESFTTFFSDTGSGRYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PR+I VDLEP +D +R+G + LF P+ I G+ A NN+A+GHYT G EL+D+VLD + Sbjct: 61 PRSIFVDLEPTVVDEIRTGTYKKLFHPEQMITGKEDAANNYARGHYTVGKELIDTVLDRI 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 R+ +NC LQGF + HS GGGTGSG +LL+ ++ +Y + FS+ P+P+VS VV Sbjct: 121 RRLADNCSGLQGFFVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYN+ L+ H +E++D + +DNEA+YDIC R L + P+Y +LN ++S +S +T SL Sbjct: 181 EPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDVERPSYTNLNRIISQVVSSITASL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RF G LN DL + N+VP+PR+HF + + PL + + AL+V ++T F+ N M Sbjct: 241 RFDGALNVDLNEFQTNLVPYPRIHFPLAAYTPLISAEKAYHEALSVSDITNSCFEPANQM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR- 359 CDPRHG+Y+ V ++RG + K+V+ + AI++K + FV+W P KV + PP Sbjct: 301 VKCDPRHGKYMAVCLLYRGDVVPKDVNTAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTV 360 Query: 360 -------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAE 412 + + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EFTEA Sbjct: 361 VPGGDLAKVPRAVCMLSNTTAIAEAWSRLDYKFDLMYAKRAFVHWYVGEGMEEGEFTEAR 420 Query: 413 SNMNDLVSEYQQ 424 ++ L +Y++ Sbjct: 421 EDLAALEKDYEE 432 >5UBQ-C nrPDB Length = 441 Score = 367 bits (942), Expect = e-102, Method: Compositional matrix adjust. Identities = 185/441 (41%), Positives = 276/441 (62%), Gaps = 10/441 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQL--ERISVYYNEASSHK 58 MRE++ I GQ G Q+G WE+ EHGI P G D + + + +++E + K Sbjct: 1 MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGK 60 Query: 59 YVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLD 118 +VPRA+ +DLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E+VD LD Sbjct: 61 HVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLD 120 Query: 119 VVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDT 178 +RK +NC LQGF + +S+GGGTGSG+G+LL+ ++ +Y + F++ PSP+VS Sbjct: 121 RIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTA 180 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VVEPYN+ LS H L+E+TD +DNEA+YDIC R L + PTY +LN L++ +S +T Sbjct: 181 VVEPYNSILSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTA 240 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKN 298 SLRF G LN D+ + N+VP+PR+HF + +AP+ + + L+V E+T F+ N Sbjct: 241 SLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPAN 300 Query: 299 MMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP 358 MMA CDPRHG+Y+ + ++RG + K+V+ + I++K + FV+W P KV + PP Sbjct: 301 MMAKCDPRHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQPP 360 Query: 359 R--------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTE 410 + + I NSTAI E+F R+ +F M+ ++AF+HWY GEGM+E EF+E Sbjct: 361 TVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 420 Query: 411 AESNMNDLVSEYQQYQDATAE 431 A ++ L +Y++ TAE Sbjct: 421 AREDLAALEKDYEEVGIETAE 441 >5MLV-E nrPDB Length = 455 Score = 362 bits (929), Expect = e-100, Method: Compositional matrix adjust. Identities = 184/457 (40%), Positives = 282/457 (61%), Gaps = 18/457 (3%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLER------ISVYYNEA 54 MRE++ + GQ G QIG WE+ EHGI P G +S++ +++E Sbjct: 1 MREVISVHVGQAGVQIGNACWELYCLEHGIGPDGFPTENSEVHKNNSYLNDGFGTFFSET 60 Query: 55 SSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVD 114 K+VPR+I VDLEP +D VR+G + LF P+ + G+ A NN+A+GHYT G E++D Sbjct: 61 GQGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKEDASNNYARGHYTVGKEMID 120 Query: 115 SVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPK 174 SVL+ +R+ +NC LQGF + HS GGGTGSG+G LL+ ++ EY + FSV P+P+ Sbjct: 121 SVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSVYPAPQ 180 Query: 175 VSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMS 234 VS +VVEPYN+ L+ H ++N+D T+ +DNEA YDIC R L + PTY +LN L++ +S Sbjct: 181 VSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRLIAQVVS 240 Query: 235 GVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMF 294 +T SLRF G LN DL + N+VP+PR+HF + ++P+ + + + +V E+T Q F Sbjct: 241 SITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVSAAKAFHESNSVQEITNQCF 300 Query: 295 DAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVC 354 + N M CDPR GRY+ ++RG + ++V + +I+S+ + FV+W P K+ +C Sbjct: 301 EPYNQMVKCDPRTGRYMATCLLYRGDVIPRDVQAAVTSIKSRRTIQFVDWCPTGFKIGIC 360 Query: 355 DIPPRGLKMSS--------TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEM 406 PP+ + S + N+T+I E + R+ +F M+ ++AF+HWY GEGM+E Sbjct: 361 YEPPQHVPGSGIAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEG 420 Query: 407 EFTEAESNMNDLVSEYQQY-QDATAEEEGEMYEDDDE 442 EF+EA ++ L +Y++ QD+ + EMYE D+E Sbjct: 421 EFSEAREDLAALERDYEEVGQDSM---DNEMYEADEE 454 >2XRP-B nrPDB Length = 452 Score = 356 bits (913), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 177/434 (40%), Positives = 264/434 (60%), Gaps = 10/434 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQL--ERISVYYNEASSHK 58 MRE + I GQ G QIG WE+ EHGI P G D + + + +++E + K Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60 Query: 59 YVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLD 118 +VPRA+ VDLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E++D VLD Sbjct: 61 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 120 Query: 119 VVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDT 178 +RK + C LQGF + HS GGGTGSG +LL+ ++ +Y + FS+ P+P+VS Sbjct: 121 RIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 180 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T Sbjct: 181 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 240 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKN 298 SLRF G LN DL + N+VP+PR HF + +AP+ + + L+V E+T F+ N Sbjct: 241 SLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 300 Query: 299 MMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP 358 M CDPRHG+Y+ ++RG + K+V+ + I++K + FV+W P KV + PP Sbjct: 301 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPP 360 Query: 359 R--------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTE 410 ++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+E Sbjct: 361 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 420 Query: 411 AESNMNDLVSEYQQ 424 A +M L +Y++ Sbjct: 421 AREDMAALEKDYEE 434 >5W3H-A nrPDB Length = 447 Score = 353 bits (906), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 184/445 (41%), Positives = 274/445 (61%), Gaps = 12/445 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNY---VGDSDLQLERISVYYNEASSH 57 MRE++ I GQ G QIG WE+ S EHGI P G+ + E S +++E Sbjct: 1 MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYG 60 Query: 58 KYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVL 117 K+VPRAI VDLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E++ VL Sbjct: 61 KFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVL 120 Query: 118 DVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSD 177 D +RK + CD LQGF THSLGGGTGSG+G+LL+ ++ EY + F+V P+P+VS Sbjct: 121 DRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVST 180 Query: 178 TVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVT 237 +VVEPYN L+ H +E+ D T+ +DNEA+YD+C R L + P++ +LN+L++ +S VT Sbjct: 181 SVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVT 240 Query: 238 TSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAK 297 SLRF G LN DL + N+VP+PR+HF + ++P+ ++ + + +V E+T F+ Sbjct: 241 ASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPG 300 Query: 298 NMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIP 357 N M CDPR G+Y+ ++RG + ++V + +++K + V+W P K+ +C P Sbjct: 301 NQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEP 360 Query: 358 PRGLKMSS--------TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 409 P S + N+T+I E +KRI +F M+ ++AF+HWY GEGM+E EFT Sbjct: 361 PTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFT 420 Query: 410 EAESNMNDLVSEYQQY-QDATAEEE 433 EA ++ L +Y + D+ AEEE Sbjct: 421 EAREDLAALERDYIEVGADSYAEEE 445 >5ND4-A nrPDB Length = 412 Score = 341 bits (875), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 173/431 (40%), Positives = 253/431 (58%), Gaps = 32/431 (7%) Query: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVP 61 RE + I GQ G QIG WE+ EHGI P G +VP Sbjct: 1 RECISIHVGQAGVQIGNACWELYCLEHGIQPDG------------------------HVP 36 Query: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVR 121 RA+ VDLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E++D VLD +R Sbjct: 37 RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIR 96 Query: 122 KECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVE 181 K + C LQGF + HS GGGTGSG +LL+ ++ +Y + FS+ P+P+VS VVE Sbjct: 97 KLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVE 156 Query: 182 PYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLR 241 PYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T SLR Sbjct: 157 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLR 216 Query: 242 FPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMA 301 F G LN DL + N+VP+PR HF + +AP+ + + L+V E+T F+ N M Sbjct: 217 FDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV 276 Query: 302 ACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR-- 359 CDPRHG+Y+ ++RG + K+V+ + I++K + FV+W P KV + PP Sbjct: 277 KCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVV 336 Query: 360 ------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAES 413 ++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA Sbjct: 337 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE 396 Query: 414 NMNDLVSEYQQ 424 +M L +Y++ Sbjct: 397 DMAALEKDYEE 407 >2BTQ-B nrPDB Length = 426 Score = 307 bits (786), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 165/432 (38%), Positives = 249/432 (57%), Gaps = 9/432 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYV-GDSDLQLERISVYYNEASSHKY 59 +REI+ I GQCGNQI FW + EHG+ +G G + + V++++ KY Sbjct: 1 VREILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKEGSNAAANSNMEVFFHKVRDGKY 60 Query: 60 VPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDV 119 VPRA+LVDLEPG + + G LF + + GA NNWA+G+ EG +++D +++V Sbjct: 61 VPRAVLVDLEPGVIARIEGGDMSQLFDESSIVRKIPGAANNWARGYNVEGEKVIDQIMNV 120 Query: 120 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTV 179 + E LQGF +THS+GGG+GSG+G+L++ ++R+ YP + + TFSVVPSP +SD+ Sbjct: 121 IDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSPLISDSA 180 Query: 180 VEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTS 239 VEPYNA L++ ++++N D +DNEAL+ I L +P Y DLN++++ +S VT S Sbjct: 181 VEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLN-RSPNYMDLNNIIALIVSSVTAS 239 Query: 240 LRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNM 299 LRFPG+LN DL + N+VPFP HF FAP+ G + P+L ++ F N Sbjct: 240 LRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMRGAGQEGQVRTNFPDLARETFAQDNF 299 Query: 300 MAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIP--NNVKVAVCDIP 357 AA D + G YL + +FRG + K+VDE M I + S + ++P +K+ + Sbjct: 300 TAAIDWQQGVYLAASALFRGDVKAKDVDENMATI--RKSLNYASYMPASGGLKLGYAETA 357 Query: 358 PRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMND 417 P G S + N T I +F+R+ QF MF A+ HWY G+ +A N Sbjct: 358 PEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSRDMMAKAR---NQ 414 Query: 418 LVSEYQQYQDAT 429 + + Q Y+DA+ Sbjct: 415 IATLAQSYRDAS 426 >1Z5V-A nrPDB Length = 474 Score = 295 bits (754), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 150/439 (34%), Positives = 253/439 (57%), Gaps = 22/439 (5%) Query: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVP 61 REI+ +Q GQCGNQIG +FW+ + EHGI P + +R V++ +A Y+P Sbjct: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEAIVEEFATEGTDRKDVFFYQADDEHYIP 62 Query: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 119 RA+L+DLEP + S+ + + L+ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 Query: 120 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSP-KVSDT 178 + +E + D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ T+SV P+ ++SD Sbjct: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT Sbjct: 182 VVQPYNSLLTLKRLTQNADCLVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGS-QQYRALTVPELTQQMFDAK 297 +LR+PG +N DL L +++P PRLHF M G+ PLT S R TV ++ +++ K Sbjct: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 Query: 298 NMMAACDPRHGR-------YLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVK 350 N+M + GR Y+ + + +G + +V + + I+ + + F+ W P +++ Sbjct: 302 NVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQ 357 Query: 351 VAVCDIP---PRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEME 407 VA+ P ++S + N T+I LF+R Q+ + +R+AFL + E M + Sbjct: 358 VALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDN 417 Query: 408 FTEAESN---MNDLVSEYQ 423 F E +++ + L+ EY Sbjct: 418 FDEMDTSREIVQQLIDEYH 436 >2BTQ-A nrPDB Length = 473 Score = 288 bits (738), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 159/434 (36%), Positives = 244/434 (56%), Gaps = 7/434 (1%) Query: 5 VHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYN---EASSHKYVP 61 + + GQ GNQI A FW+ + EHGIDP S +++ E+SS YVP Sbjct: 7 IVVSIGQAGNQIAASFWKTVCLEHGIDPLTGQTAPGVAPRGNWSSFFSKLGESSSGSYVP 66 Query: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVR 121 RAI+VDLEP +D+V++ + G LF P N I GAG N+A G+ G E++ V+ + Sbjct: 67 RAIMVDLEPSVIDNVKATS-GSLFNPANLISRTEGAGGNFAVGYLGAGREVLPEVMSRLD 125 Query: 122 KECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVE 181 E + CD + G + H++GGGTGSG G LLI ++E+Y + + + +V+PSP+VS V E Sbjct: 126 YEIDKCDNVGGIIVLHAIGGGTGSGFGALLIESLKEKYGEIPVLSCAVLPSPQVSSVVTE 185 Query: 182 PYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLR 241 PYN +++ L + D DNEAL+D+ R + +PT DLN L++ ++G+T S+R Sbjct: 186 PYNTVFALNTLRRSADACLIFDNEALFDLAHRKWNIESPTVDDLNLLITEALAGITASMR 245 Query: 242 FPGQLNAD--LRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNM 299 F G L + LR+L N+VP P LHF M FAPLT ++ L + E+ + +FD ++ Sbjct: 246 FSGFLTVEISLRELLTNLVPQPSLHFLMCAFAPLTPPDRSKFEELGIEEMIKSLFDNGSV 305 Query: 300 MAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR 359 AAC P GR+L+ A ++RG M K + + LA + WIP K+ + P Sbjct: 306 FAACSPMEGRFLSTAVLYRGIMEDKPLADAALAAM-REKLPLTYWIPTAFKIGYVEQPGI 364 Query: 360 GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLV 419 + S + N+T I + RI F +++RKAF +WY EGM E + ++ +LV Sbjct: 365 SHRKSMVLLANNTEIARVLDRICHNFDKLWQRKAFANWYLNEGMSEEQINVLRASAQELV 424 Query: 420 SEYQQYQDATAEEE 433 YQ +++ A+ + Sbjct: 425 QSYQVAEESGAKAK 438 >5FM1-C nrPDB Length = 473 Score = 208 bits (530), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 136/470 (28%), Positives = 232/470 (49%), Gaps = 29/470 (6%) Query: 3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPSG-NYVGDSDLQLER-ISVYYNEASSHKYV 60 EI+ +QAGQCGN +G W ++ EH I G + + DS + + ++ E S +K+ Sbjct: 4 EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRNKFT 63 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGA--GNNWAKGHYTEGAELVDSVLD 118 PRAI++D EP + V + F F P N GA GN+WA G Y G D +L+ Sbjct: 64 PRAIMMDSEPSVIADVEN-TFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILN 121 Query: 119 VVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDT 178 + KE ++ D +GFQL HS+ GGTGSG+G+ L+ + + YP +I+ T+SV P+ + S+ Sbjct: 122 KIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPA-RSSEV 180 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VV+ YN L++ +L+E++D T DN +L +I + + N L+S +S VT Sbjct: 181 VVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISSVTN 240 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTA---RGSQQYRALTVPELTQQMFD 295 S+RFP + + + + ++P P LHF P F P T+ ++ + ++ + D Sbjct: 241 SIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLD 300 Query: 296 AKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAV-- 353 N + + + Y V G + +++ M +Q + F W + + V + Sbjct: 301 PSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRAMTKLQQR--IKFPSWSSSAMHVNIGR 358 Query: 354 ----CDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY-TGEGMDEM-- 406 + P ++S + N + + +F+ F +F + AFL+ Y G+ M Sbjct: 359 RSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQN 418 Query: 407 ---EFTEA----ESNMNDLV-SEYQQYQDATAEEEGEMYEDDDEESEAQG 448 EF E+ +S M D V +E Y D ++ M + +E+ +A G Sbjct: 419 VQDEFAESREVVQSLMEDYVAAEQDSYLDDVLVDDENMVGELEEDLDADG 468 >3ZID-A nrPDB Length = 373 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 43/166 (25%), Positives = 75/166 (45%), Gaps = 19/166 (11%) Query: 96 GAGNNWAKGH--YTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLIS 153 G G N +KG + E E++ L+ + K + D + F +T S+ GGTGS L+I Sbjct: 74 GVGANRSKGKQGFWENQEMI---LEEIEKRG-DFDLI--FVMT-SVSGGTGSSFSPLMIH 126 Query: 154 KVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVE-NTDETYCIDNEALY---- 208 ++++ Y + + +V+P + + + NA + +++E D +DN+ L Sbjct: 127 ELKKRYKNATIVPIAVLPFRE--EGTIYLQNAAFCLREMIEVEADGMILVDNQYLKRFSG 184 Query: 209 DICFRTLKLATPTYGDLNHLVSAT---MSGVTTSLRFPGQLNADLR 251 DI ++ T L L+ A M VT F +N LR Sbjct: 185 DIASAYDRINTMVAQRLLFLIEALDSEMLSVTDLGDFKTVMNGGLR 230 >4XCQ-A nrPDB Length = 318 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 7/72 (9%) Query: 138 SLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTD 197 ++ GGTGSG+ ++ ++ YP++ V+ PK ++ + E NA + ++ +T+ Sbjct: 97 TMAGGTGSGITPPILGLAKQMYPNKHFGFVGVL--PKATEDIDEHMNAIACWNDIMRSTN 154 Query: 198 E-----TYCIDN 204 E Y +DN Sbjct: 155 EGKDISIYLLDN 166 >3V3T-A nrPDB Length = 360 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 37/72 (51%), Gaps = 7/72 (9%) Query: 138 SLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTD 197 ++ GG GSG+ ++ ++ YP++ V+ PK ++ + E NA + ++ +T+ Sbjct: 97 TMAGGAGSGITPPILGLAKQMYPNKHFGFVGVL--PKATEDIDEHMNAIACWNDIMRSTN 154 Query: 198 E-----TYCIDN 204 E Y +DN Sbjct: 155 EGKDISIYLLDN 166 >5CKV-A nrPDB Length = 472 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 8/85 (9%) Query: 252 KLAVNMVPFPRLHFF-------MPGFAPLTAR-GSQQYRALTVPELTQQMFDAKNMMAAC 303 KL NM P + + PG L +R G+ + R L P + + ++ C Sbjct: 316 KLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQC 375 Query: 304 DPRHGRYLTVATVFRGRMSMKEVDE 328 DP HG +T F+ R + VDE Sbjct: 376 DPMHGNTHESSTGFKTRHFDRIVDE 400 >5HUD-A nrPDB Length = 472 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 10/129 (7%) Query: 204 NEALYDICFRTLKLATPTYG-DLNHLVSATMSGVTTSLRF-PGQLNADLRKLAVNMVPFP 261 NE LYD+ L + T G D H+ A+M ++ PG + A + P Sbjct: 278 NEELYDLSAHQLWIGERTRGMDDFHVNFASMISNPIGIKIGPGITPEEAVAYADKLDPN- 336 Query: 262 RLHFFMPGFAPLTAR-GSQQYRALTVPELTQQM-FDAKNMMAACDPRHGRYLTVATVFRG 319 F PG + AR G + R++ +P + Q + ++ DP HG T + ++ Sbjct: 337 ----FEPGRLTIVARMGHDKVRSV-LPGVIQAVEASGHKVIWQSDPMHGNTFTASNGYKT 391 Query: 320 RMSMKEVDE 328 R K +DE Sbjct: 392 RHFDKVIDE 400 >2OZX-A nrPDB Length = 125 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 33/74 (44%), Gaps = 14/74 (18%) Query: 98 GNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHS----------LGGGTGSGM 147 G WA+ H A++ D V ++K+ +C+CL G +++H G Sbjct: 46 GYKWAEYH----ADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQ 101 Query: 148 GTLLISKVREEYPD 161 + K++ +YPD Sbjct: 102 HAISTEKIKAKYPD 115 >5IM3-A nrPDB Length = 963 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 6/66 (9%) Query: 371 STAIQELFKRISEQFTAMFRRK----AFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 426 S+ I + +R++EQ TA F+R+ +H E D++E + + +Y Y+ Sbjct: 68 SSRIHDTVRRLTEQVTATFKRRMPSGGTIH--IEEIQDQVELALMRAGEQKVARDYVIYR 125 Query: 427 DATAEE 432 +A A E Sbjct: 126 EARAAE 131 >2HW4-A nrPDB Length = 144 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 33/74 (44%), Gaps = 14/74 (18%) Query: 98 GNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHS----------LGGGTGSGM 147 G WA+ H A++ D V ++K+ +C+CL G +++H G Sbjct: 65 GYKWAEYH----ADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQ 120 Query: 148 GTLLISKVREEYPD 161 + K++ +YPD Sbjct: 121 HAISTEKIKAKYPD 134 >3R44-A nrPDB Length = 517 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 23/37 (62%), Gaps = 2/37 (5%) Query: 107 TEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGT 143 T GA + ++++ + +N + +QG+ LT S GGGT Sbjct: 291 TGGAPMPEALIKIY--AAKNIEVVQGYALTESCGGGT 325 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5IJ0-B nrPDB 722 0.0 6GJ4-B nrPDB 697 0.0 5UCY-B nrPDB 690 0.0 6E88-B nrPDB 686 0.0 4FFB-B nrPDB 662 0.0 6E88-A nrPDB 659 0.0 2XRP-B nrPDB 659 0.0 5MLV-E nrPDB 650 0.0 5MLV-I nrPDB 648 0.0 5UBQ-C nrPDB 643 0.0 5W3H-A nrPDB 630 0.0 5ND4-A nrPDB 619 e-178 1Z5V-A nrPDB 549 e-156 2BTQ-A nrPDB 536 e-153 2BTQ-B nrPDB 524 e-149 5FM1-C nrPDB 504 e-143 Sequences not found previously or not previously below threshold: 3ZID-A nrPDB 67 2e-11 2R6R-1 nrPDB 39 0.004 4XCQ-A nrPDB 38 0.008 3V3T-A nrPDB 35 0.055 6G58-A nrPDB 35 0.077 2VAP-A nrPDB 34 0.12 4XD9-B nrPDB 33 0.23 6G4W-q nrPDB 32 0.72 6GI9-A nrPDB 31 1.4 2VVG-A nrPDB 30 1.6 5IM3-A nrPDB 30 1.8 1BWR-A nrPDB 30 2.1 1MDA-H nrPDB 30 2.4 5T6E-A nrPDB 29 3.3 5HY3-B nrPDB 29 3.3 >5IJ0-B nrPDB Length = 426 Score = 722 bits (1864), Expect = 0.0, Method: Composition-based stats. Identities = 426/426 (100%), Positives = 426/426 (100%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV Sbjct: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV Sbjct: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL Sbjct: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM Sbjct: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG Sbjct: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQ 426 EYQQYQ Sbjct: 421 EYQQYQ 426 >6GJ4-B nrPDB Length = 445 Score = 697 bits (1798), Expect = 0.0, Method: Composition-based stats. Identities = 403/430 (93%), Positives = 420/430 (97%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDP+G+Y GDSDLQLERI+VYYNEA+ +KYV Sbjct: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRAILVDLEPGTMDSVRSG FG +FRPDNF+FGQSGAGNNWAKGHYTEGAELVDSVLDVV Sbjct: 61 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKE E+CDCLQGFQLTHSLGGGTGSGMGTLLISK+REEYPDRIMNTFSV+PSPKVSDTVV Sbjct: 121 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVENTDETYCIDNEALYDICFRTLKL TPTYGDLNHLVSATMSGVTT L Sbjct: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLT+RGSQQYRALTVPELTQQMFD+KNMM Sbjct: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AACDPRHGRYLTVA +FRGRMSMKEVDEQML +Q+KNSSYFVEWIPNNVK AVCDIPPRG Sbjct: 301 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKMS+TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQDATA 430 EYQQYQDATA Sbjct: 421 EYQQYQDATA 430 >5UCY-B nrPDB Length = 429 Score = 690 bits (1780), Expect = 0.0, Method: Composition-based stats. Identities = 374/429 (87%), Positives = 402/429 (93%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQ GQCGNQIGAKFWEVISDEHGIDP+G Y GDSDLQLERI+VYYNEA+ +YV Sbjct: 1 MREIVHIQGGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGRYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRAIL+DLEPGTMDSVR+G FG LFRPDNF+FGQ+GAGNNWAKGHYTEGAEL+DSVLDVV Sbjct: 61 PRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKE E CDCLQGFQ+THSLGGGTGSGMGTLLISKVREEYPDRIM TFSVVPSPKVSDTVV Sbjct: 121 RKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVVPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVEN DE IDNEALYDICFRTLKL TPTYGDLNHLVSA MSGVT L Sbjct: 181 EPYNATLSVHQLVENADECMVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLN+DLRKLAVN++PFPRLHFFM GFAPLT+RGSQQYRALTVPELTQQMFDAKNMM Sbjct: 241 RFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 A DPRHGRYLT + +FRGRMS KEVDEQML +Q+KNSSYFVEWIPNN+K ++CDIPP+G Sbjct: 301 CAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSICDIPPKG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKM+ TF+GNSTAIQE+FKR++EQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMAVTFVGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQDAT 429 EYQQYQDAT Sbjct: 421 EYQQYQDAT 429 >6E88-B nrPDB Length = 426 Score = 686 bits (1771), Expect = 0.0, Method: Composition-based stats. Identities = 380/426 (89%), Positives = 407/426 (95%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVH+QAGQCGNQIG+KFWEVISDEHGI P G + G++DLQLERI VYYNEA++ KYV Sbjct: 1 MREIVHVQAGQCGNQIGSKFWEVISDEHGIQPDGTFKGETDLQLERIDVYYNEANNGKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRA+LVDLEPGTMDSVRSG FG LFRPDNF+FGQSGAGNNWAKGHYTEGAELVD+VLDV+ Sbjct: 61 PRAVLVDLEPGTMDSVRSGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVLDVI 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 RKE E CDCLQGFQLTHSLGGGTGSGMGTLLISK+REEYPDRIM++FSVVPSPKVSDTVV Sbjct: 121 RKEAEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMSSFSVVPSPKVSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVENTDETYCIDNEALYDIC+RTLKL PTYGDLNHLVS TMSGVTT L Sbjct: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICYRTLKLTNPTYGDLNHLVSLTMSGVTTCL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPL+A+G+Q YRALTV ELTQQMFDAKNMM Sbjct: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLSAKGTQAYRALTVAELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AACDPRHGRYLTVA +FRGRMSM+EVDEQML +Q+KNSSYFVEWIPNNVK AVCDIPPRG Sbjct: 301 AACDPRHGRYLTVAAMFRGRMSMREVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKM++TF+GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDL+S Sbjct: 361 LKMAATFVGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLIS 420 Query: 421 EYQQYQ 426 EYQQYQ Sbjct: 421 EYQQYQ 426 >4FFB-B nrPDB Length = 463 Score = 662 bits (1709), Expect = 0.0, Method: Composition-based stats. Identities = 333/441 (75%), Positives = 393/441 (89%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREI+HI GQCGNQIGA FWE I EHG+D +G Y G D+Q ER++VY+NEASS K+V Sbjct: 1 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PR+I VDLEPGT+D+VR+ A G+LFRPDN+IFGQS AGN WAKGHYTEGAELVDSV+DV+ Sbjct: 61 PRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVI 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 R+E E CD LQGFQ+THSLGGGTGSGMGTLLISK+REE+PDR+M TFSV+PSPK SDT V Sbjct: 121 RREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKRSDTRV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVE++DET+CIDNEALYDIC RTLKL P+YGDLN+LVS+ MSGVTTSL Sbjct: 181 EPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 R+PGQLN+DLRKLAVN+VPFPRLHFFM G+APLTA GSQ +R+LTVPELTQQMFDAKNMM Sbjct: 241 RYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 AA DPR+GRYLTVA FRG++S+KEV+++M +QSKNS YFVEWIPNNV+ AVC + P+G Sbjct: 301 AAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQG 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 L M++TFI NST+IQELFKR+ +QF+AMF+RKAFLHWYT EGMDE+EF+EAESNMNDLVS Sbjct: 361 LDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVS 420 Query: 421 EYQQYQDATAEEEGEMYEDDD 441 EYQQYQ+AT E++ E+ E+ D Sbjct: 421 EYQQYQEATVEDDEEVDENGD 441 >6E88-A nrPDB Length = 434 Score = 659 bits (1700), Expect = 0.0, Method: Composition-based stats. Identities = 179/434 (41%), Positives = 270/434 (62%), Gaps = 8/434 (1%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MRE++ I GQ G QIG WE+ EHGI P G S + E + ++++ S +YV Sbjct: 1 MREVISIHVGQAGVQIGNACWELYCLEHGIQPDGTMPTQSTNEGESFTTFFSDTGSGRYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PR+I VDLEP +D +R+G + LF P+ I G+ A NN+A+GHYT G EL+D+VLD + Sbjct: 61 PRSIFVDLEPTVVDEIRTGTYKKLFHPEQMITGKEDAANNYARGHYTVGKELIDTVLDRI 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 R+ +NC LQGF + HS GGGTGSG +LL+ ++ +Y + FS+ P+P+VS VV Sbjct: 121 RRLADNCSGLQGFFVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYN+ L+ H +E++D + +DNEA+YDIC R L + P+Y +LN ++S +S +T SL Sbjct: 181 EPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDVERPSYTNLNRIISQVVSSITASL 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RF G LN DL + N+VP+PR+HF + + PL + + AL+V ++T F+ N M Sbjct: 241 RFDGALNVDLNEFQTNLVPYPRIHFPLAAYTPLISAEKAYHEALSVSDITNSCFEPANQM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR- 359 CDPRHG+Y+ V ++RG + K+V+ + AI++K + FV+W P KV + PP Sbjct: 301 VKCDPRHGKYMAVCLLYRGDVVPKDVNTAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTV 360 Query: 360 -------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAE 412 + + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EFTEA Sbjct: 361 VPGGDLAKVPRAVCMLSNTTAIAEAWSRLDYKFDLMYAKRAFVHWYVGEGMEEGEFTEAR 420 Query: 413 SNMNDLVSEYQQYQ 426 ++ L +Y++ Sbjct: 421 EDLAALEKDYEEVG 434 >2XRP-B nrPDB Length = 452 Score = 659 bits (1699), Expect = 0.0, Method: Composition-based stats. Identities = 177/440 (40%), Positives = 265/440 (60%), Gaps = 10/440 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQL--ERISVYYNEASSHK 58 MRE + I GQ G QIG WE+ EHGI P G D + + + +++E + K Sbjct: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60 Query: 59 YVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLD 118 +VPRA+ VDLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E++D VLD Sbjct: 61 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 120 Query: 119 VVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDT 178 +RK + C LQGF + HS GGGTGSG +LL+ ++ +Y + FS+ P+P+VS Sbjct: 121 RIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 180 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T Sbjct: 181 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 240 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKN 298 SLRF G LN DL + N+VP+PR HF + +AP+ + + L+V E+T F+ N Sbjct: 241 SLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 300 Query: 299 MMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP 358 M CDPRHG+Y+ ++RG + K+V+ + I++K + FV+W P KV + PP Sbjct: 301 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPP 360 Query: 359 R--------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTE 410 ++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+E Sbjct: 361 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 420 Query: 411 AESNMNDLVSEYQQYQDATA 430 A +M L +Y++ + Sbjct: 421 AREDMAALEKDYEEVGVDSV 440 >5MLV-E nrPDB Length = 455 Score = 650 bits (1678), Expect = 0.0, Method: Composition-based stats. Identities = 182/456 (39%), Positives = 280/456 (61%), Gaps = 16/456 (3%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLER------ISVYYNEA 54 MRE++ + GQ G QIG WE+ EHGI P G +S++ +++E Sbjct: 1 MREVISVHVGQAGVQIGNACWELYCLEHGIGPDGFPTENSEVHKNNSYLNDGFGTFFSET 60 Query: 55 SSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVD 114 K+VPR+I VDLEP +D VR+G + LF P+ + G+ A NN+A+GHYT G E++D Sbjct: 61 GQGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKEDASNNYARGHYTVGKEMID 120 Query: 115 SVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPK 174 SVL+ +R+ +NC LQGF + HS GGGTGSG+G LL+ ++ EY + FSV P+P+ Sbjct: 121 SVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSVYPAPQ 180 Query: 175 VSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMS 234 VS +VVEPYN+ L+ H ++N+D T+ +DNEA YDIC R L + PTY +LN L++ +S Sbjct: 181 VSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRLIAQVVS 240 Query: 235 GVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMF 294 +T SLRF G LN DL + N+VP+PR+HF + ++P+ + + + +V E+T Q F Sbjct: 241 SITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVSAAKAFHESNSVQEITNQCF 300 Query: 295 DAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVC 354 + N M CDPR GRY+ ++RG + ++V + +I+S+ + FV+W P K+ +C Sbjct: 301 EPYNQMVKCDPRTGRYMATCLLYRGDVIPRDVQAAVTSIKSRRTIQFVDWCPTGFKIGIC 360 Query: 355 DIPPRGLKMSS--------TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEM 406 PP+ + S + N+T+I E + R+ +F M+ ++AF+HWY GEGM+E Sbjct: 361 YEPPQHVPGSGIAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEG 420 Query: 407 EFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDDE 442 EF+EA ++ L +Y++ + + EMYE D+E Sbjct: 421 EFSEAREDLAALERDYEEVGQDSM--DNEMYEADEE 454 >5MLV-I nrPDB Length = 448 Score = 648 bits (1672), Expect = 0.0, Method: Composition-based stats. Identities = 331/430 (76%), Positives = 383/430 (89%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 MREIVHIQAGQCGNQ+GA FW I+DEHG+D +G Y G S+ Q ER++VY+NEA+ KYV Sbjct: 1 MREIVHIQAGQCGNQVGAAFWSTIADEHGLDSAGIYHGTSEAQHERLNVYFNEAAGGKYV 60 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 PRA+LVDLEPGTMD+V+SG FG+LFRPDN I+GQSGAGN WAKGHYTEGAEL D+VLDVV Sbjct: 61 PRAVLVDLEPGTMDAVKSGKFGNLFRPDNIIYGQSGAGNIWAKGHYTEGAELADAVLDVV 120 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 R+E E CD LQGFQLTHSLGGGTGSGMGTLL+SK+REEYPDR+M TFSV P+PK SDTVV Sbjct: 121 RREAEACDALQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRMMATFSVAPAPKSSDTVV 180 Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240 EPYNATLS+HQLVEN+DET+CIDNEAL I TLK+ +P+Y DLNHLVSA M+GVTTS Sbjct: 181 EPYNATLSMHQLVENSDETFCIDNEALSSIFANTLKIKSPSYDDLNHLVSAVMAGVTTSF 240 Query: 241 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 300 RFPG+LN+DLRKLAVNMVPFPRLHFFM GFAPL A GS ++A++VPELTQQMFDA NMM Sbjct: 241 RFPGELNSDLRKLAVNMVPFPRLHFFMVGFAPLAAIGSSSFQAVSVPELTQQMFDANNMM 300 Query: 301 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 360 A DPRHGRYLTVA +FRG++SMKEVDEQ+ ++Q+KNS+YFVEWIP+NV AVC +PP+ Sbjct: 301 VAADPRHGRYLTVAALFRGKVSMKEVDEQIRSVQTKNSAYFVEWIPDNVLKAVCSVPPKD 360 Query: 361 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 LKMS+TFIGNST+IQE+F+R+ +QF+AMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS Sbjct: 361 LKMSATFIGNSTSIQEIFRRLGDQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 420 Query: 421 EYQQYQDATA 430 EYQQYQ+A Sbjct: 421 EYQQYQEAGI 430 >5UBQ-C nrPDB Length = 441 Score = 643 bits (1659), Expect = 0.0, Method: Composition-based stats. Identities = 185/441 (41%), Positives = 276/441 (62%), Gaps = 10/441 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQL--ERISVYYNEASSHK 58 MRE++ I GQ G Q+G WE+ EHGI P G D + + + +++E + K Sbjct: 1 MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGK 60 Query: 59 YVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLD 118 +VPRA+ +DLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E+VD LD Sbjct: 61 HVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLD 120 Query: 119 VVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDT 178 +RK +NC LQGF + +S+GGGTGSG+G+LL+ ++ +Y + F++ PSP+VS Sbjct: 121 RIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTA 180 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VVEPYN+ LS H L+E+TD +DNEA+YDIC R L + PTY +LN L++ +S +T Sbjct: 181 VVEPYNSILSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTA 240 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKN 298 SLRF G LN D+ + N+VP+PR+HF + +AP+ + + L+V E+T F+ N Sbjct: 241 SLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPAN 300 Query: 299 MMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP 358 MMA CDPRHG+Y+ + ++RG + K+V+ + I++K + FV+W P KV + PP Sbjct: 301 MMAKCDPRHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQPP 360 Query: 359 R--------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTE 410 + + I NSTAI E+F R+ +F M+ ++AF+HWY GEGM+E EF+E Sbjct: 361 TVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 420 Query: 411 AESNMNDLVSEYQQYQDATAE 431 A ++ L +Y++ TAE Sbjct: 421 AREDLAALEKDYEEVGIETAE 441 >5W3H-A nrPDB Length = 447 Score = 630 bits (1624), Expect = 0.0, Method: Composition-based stats. Identities = 183/446 (41%), Positives = 273/446 (61%), Gaps = 12/446 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYV---GDSDLQLERISVYYNEASSH 57 MRE++ I GQ G QIG WE+ S EHGI P G+ E S +++E Sbjct: 1 MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYG 60 Query: 58 KYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVL 117 K+VPRAI VDLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E++ VL Sbjct: 61 KFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVL 120 Query: 118 DVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSD 177 D +RK + CD LQGF THSLGGGTGSG+G+LL+ ++ EY + F+V P+P+VS Sbjct: 121 DRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVST 180 Query: 178 TVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVT 237 +VVEPYN L+ H +E+ D T+ +DNEA+YD+C R L + P++ +LN+L++ +S VT Sbjct: 181 SVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVT 240 Query: 238 TSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAK 297 SLRF G LN DL + N+VP+PR+HF + ++P+ ++ + + +V E+T F+ Sbjct: 241 ASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPG 300 Query: 298 NMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIP 357 N M CDPR G+Y+ ++RG + ++V + +++K + V+W P K+ +C P Sbjct: 301 NQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEP 360 Query: 358 PRGLK--------MSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 409 P + + N+T+I E +KRI +F M+ ++AF+HWY GEGM+E EFT Sbjct: 361 PTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFT 420 Query: 410 EAESNMNDLVSEYQQYQ-DATAEEEG 434 EA ++ L +Y + D+ AEEE Sbjct: 421 EAREDLAALERDYIEVGADSYAEEEE 446 >5ND4-A nrPDB Length = 412 Score = 619 bits (1596), Expect = e-178, Method: Composition-based stats. Identities = 173/436 (39%), Positives = 254/436 (58%), Gaps = 32/436 (7%) Query: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVP 61 RE + I GQ G QIG WE+ EHGI P G +VP Sbjct: 1 RECISIHVGQAGVQIGNACWELYCLEHGIQPDG------------------------HVP 36 Query: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVR 121 RA+ VDLEP +D VR+G + LF P+ I G+ A NN+A+GHYT G E++D VLD +R Sbjct: 37 RAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIR 96 Query: 122 KECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVE 181 K + C LQGF + HS GGGTGSG +LL+ ++ +Y + FS+ P+P+VS VVE Sbjct: 97 KLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVE 156 Query: 182 PYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLR 241 PYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T SLR Sbjct: 157 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLR 216 Query: 242 FPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMA 301 F G LN DL + N+VP+PR HF + +AP+ + + L+V E+T F+ N M Sbjct: 217 FDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV 276 Query: 302 ACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR-- 359 CDPRHG+Y+ ++RG + K+V+ + I++K + FV+W P KV + PP Sbjct: 277 KCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVV 336 Query: 360 ------GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAES 413 ++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA Sbjct: 337 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE 396 Query: 414 NMNDLVSEYQQYQDAT 429 +M L +Y++ + Sbjct: 397 DMAALEKDYEEVGVDS 412 >1Z5V-A nrPDB Length = 474 Score = 549 bits (1414), Expect = e-156, Method: Composition-based stats. Identities = 148/437 (33%), Positives = 248/437 (56%), Gaps = 14/437 (3%) Query: 2 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVP 61 REI+ +Q GQCGNQIG +FW+ + EHGI P + +R V++ +A Y+P Sbjct: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEAIVEEFATEGTDRKDVFFYQADDEHYIP 62 Query: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 119 RA+L+DLEP + S+ + + L+ P+N + GAGNNWA G +++G ++ + + D+ Sbjct: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121 Query: 120 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSP-KVSDT 178 + +E + D L+GF L HS+ GGTGSG+G+ L+ ++ + YP +++ T+SV P+ ++SD Sbjct: 122 IDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDV 181 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT Sbjct: 182 VVQPYNSLLTLKRLTQNADCLVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGS-QQYRALTVPELTQQMFDAK 297 +LR+PG +N DL L +++P PRLHF M G+ PLT S R TV ++ +++ K Sbjct: 242 TLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPK 301 Query: 298 NMMAACDPRHGR---YLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVC 354 N+M + Y+ + + +G + +V + + I+ + + F+ W P +++VA+ Sbjct: 302 NVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALS 361 Query: 355 DIPP---RGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEA 411 P ++S + N T+I LF+R Q+ + +R+AFL + E M + F E Sbjct: 362 RKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEM 421 Query: 412 ---ESNMNDLVSEYQQY 425 + L+ EY Sbjct: 422 DTSREIVQQLIDEYHAA 438 >2BTQ-A nrPDB Length = 473 Score = 536 bits (1382), Expect = e-153, Method: Composition-based stats. Identities = 159/434 (36%), Positives = 244/434 (56%), Gaps = 7/434 (1%) Query: 5 VHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYN---EASSHKYVP 61 + + GQ GNQI A FW+ + EHGIDP S +++ E+SS YVP Sbjct: 7 IVVSIGQAGNQIAASFWKTVCLEHGIDPLTGQTAPGVAPRGNWSSFFSKLGESSSGSYVP 66 Query: 62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVR 121 RAI+VDLEP +D+V++ + G LF P N I GAG N+A G+ G E++ V+ + Sbjct: 67 RAIMVDLEPSVIDNVKATS-GSLFNPANLISRTEGAGGNFAVGYLGAGREVLPEVMSRLD 125 Query: 122 KECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVE 181 E + CD + G + H++GGGTGSG G LLI ++E+Y + + + +V+PSP+VS V E Sbjct: 126 YEIDKCDNVGGIIVLHAIGGGTGSGFGALLIESLKEKYGEIPVLSCAVLPSPQVSSVVTE 185 Query: 182 PYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLR 241 PYN +++ L + D DNEAL+D+ R + +PT DLN L++ ++G+T S+R Sbjct: 186 PYNTVFALNTLRRSADACLIFDNEALFDLAHRKWNIESPTVDDLNLLITEALAGITASMR 245 Query: 242 FPGQLNAD--LRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNM 299 F G L + LR+L N+VP P LHF M FAPLT ++ L + E+ + +FD ++ Sbjct: 246 FSGFLTVEISLRELLTNLVPQPSLHFLMCAFAPLTPPDRSKFEELGIEEMIKSLFDNGSV 305 Query: 300 MAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR 359 AAC P GR+L+ A ++RG M K + + LA + WIP K+ + P Sbjct: 306 FAACSPMEGRFLSTAVLYRGIMEDKPLADAALAAM-REKLPLTYWIPTAFKIGYVEQPGI 364 Query: 360 GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLV 419 + S + N+T I + RI F +++RKAF +WY EGM E + ++ +LV Sbjct: 365 SHRKSMVLLANNTEIARVLDRICHNFDKLWQRKAFANWYLNEGMSEEQINVLRASAQELV 424 Query: 420 SEYQQYQDATAEEE 433 YQ +++ A+ + Sbjct: 425 QSYQVAEESGAKAK 438 >2BTQ-B nrPDB Length = 426 Score = 524 bits (1349), Expect = e-149, Method: Composition-based stats. Identities = 165/432 (38%), Positives = 249/432 (57%), Gaps = 9/432 (2%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYV-GDSDLQLERISVYYNEASSHKY 59 +REI+ I GQCGNQI FW + EHG+ +G G + + V++++ KY Sbjct: 1 VREILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKEGSNAAANSNMEVFFHKVRDGKY 60 Query: 60 VPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDV 119 VPRA+LVDLEPG + + G LF + + GA NNWA+G+ EG +++D +++V Sbjct: 61 VPRAVLVDLEPGVIARIEGGDMSQLFDESSIVRKIPGAANNWARGYNVEGEKVIDQIMNV 120 Query: 120 VRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTV 179 + E LQGF +THS+GGG+GSG+G+L++ ++R+ YP + + TFSVVPSP +SD+ Sbjct: 121 IDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSPLISDSA 180 Query: 180 VEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTS 239 VEPYNA L++ ++++N D +DNEAL+ I L +P Y DLN++++ +S VT S Sbjct: 181 VEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLN-RSPNYMDLNNIIALIVSSVTAS 239 Query: 240 LRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNM 299 LRFPG+LN DL + N+VPFP HF FAP+ G + P+L ++ F N Sbjct: 240 LRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMRGAGQEGQVRTNFPDLARETFAQDNF 299 Query: 300 MAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIP--NNVKVAVCDIP 357 AA D + G YL + +FRG + K+VDE M I + S + ++P +K+ + Sbjct: 300 TAAIDWQQGVYLAASALFRGDVKAKDVDENMATI--RKSLNYASYMPASGGLKLGYAETA 357 Query: 358 PRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMND 417 P G S + N T I +F+R+ QF MF A+ HWY G+ +A N Sbjct: 358 PEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSRDMMAKAR---NQ 414 Query: 418 LVSEYQQYQDAT 429 + + Q Y+DA+ Sbjct: 415 IATLAQSYRDAS 426 >5FM1-C nrPDB Length = 473 Score = 504 bits (1298), Expect = e-143, Method: Composition-based stats. Identities = 133/470 (28%), Positives = 230/470 (48%), Gaps = 29/470 (6%) Query: 3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPSG-NYVGDSDLQLER-ISVYYNEASSHKYV 60 EI+ +QAGQCGN +G W ++ EH I G + + DS + + ++ E S +K+ Sbjct: 4 EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRNKFT 63 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGA--GNNWAKGHYTEGAELVDSVLD 118 PRAI++D EP + V + F F P N GA GN+WA G Y G D +L+ Sbjct: 64 PRAIMMDSEPSVIADVEN-TFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILN 121 Query: 119 VVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDT 178 + KE ++ D +GFQL HS+ GGTGSG+G+ L+ + + YP +I+ T+SV P+ + S+ Sbjct: 122 KIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPA-RSSEV 180 Query: 179 VVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTT 238 VV+ YN L++ +L+E++D T DN +L +I + + N L+S +S VT Sbjct: 181 VVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISSVTN 240 Query: 239 SLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTA---RGSQQYRALTVPELTQQMFD 295 S+RFP + + + + ++P P LHF P F P T+ ++ + ++ + D Sbjct: 241 SIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLD 300 Query: 296 AKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAV-- 353 N + + + Y V G + +++ M +Q + F W + + V + Sbjct: 301 PSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRAMTKLQQR--IKFPSWSSSAMHVNIGR 358 Query: 354 ----CDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY-TGEGMDEM-- 406 + P ++S + N + + +F+ F +F + AFL+ Y G+ M Sbjct: 359 RSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQN 418 Query: 407 ---EFTEAESNMNDLVSEY-----QQYQDATAEEEGEMYEDDDEESEAQG 448 EF E+ + L+ +Y Y D ++ M + +E+ +A G Sbjct: 419 VQDEFAESREVVQSLMEDYVAAEQDSYLDDVLVDDENMVGELEEDLDADG 468 >3ZID-A nrPDB Length = 373 Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 73/423 (17%), Positives = 140/423 (33%), Gaps = 57/423 (13%) Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60 M ++ + GQCGN+I R++ YY++ V Sbjct: 1 MLNVLMLGVGQCGNRILDAVNRQ-----------------AFGGSRLAKYYSKQRFPSRV 43 Query: 61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120 I ++ + ++ A N G G N +KG E + +L+ + Sbjct: 44 -ETIAINTAINDLKELKFTAAKDRLHVPNL----HGVGANRSKGKQGF-WENQEMILEEI 97 Query: 121 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 180 K + + S+ GGTGS L+I ++++ Y + + +V+P + + Sbjct: 98 EKRGD----FDLIFVMTSVSGGTGSSFSPLMIHELKKRYKNATIVPIAVLPFREEGTIYL 153 Query: 181 EPYNATLSIHQLVE-NTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTS 239 + NA + +++E D +DN+ L Y +N +V+ + + + Sbjct: 154 Q--NAAFCLREMIEVEADGMILVDNQYLKRFSGDI----ASAYDRINTMVAQRLLFLIEA 207 Query: 240 LRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNM 299 L DL M R+ A + + ++ E+ + N+ Sbjct: 208 LDSEMLSVTDLGDFKTVMNGGLRMGTLGYYQADKKSPSIRAAIKNSLREV--GLLYPANV 265 Query: 300 MAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR 359 A R V +G VDE +K E I + K + Sbjct: 266 DAGEAGR------AMIVIQGSREYLNVDE-----ITKEIESLTETIGHVFK-GIVIKKGE 313 Query: 360 GLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLV 419 +S + + + EL+++ + A + E EA +NDL Sbjct: 314 PRVLSVLSLERAPGLVELYEK---------AKWAIQEERERKDRARSELYEAFEQINDLE 364 Query: 420 SEY 422 Y Sbjct: 365 EIY 367 >2R6R-1 nrPDB Length = 338 Score = 39.2 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 185 ATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPG 244 A + +L E++D I N+ + ++ RTL + + +++ ++S + G+T+ + P Sbjct: 143 ALKGLEKLKESSDAYIVIHNDKIKELSNRTLTIKD-AFKEVDSVLSKAVRGITSIVVTPA 201 Query: 245 QLNADLRKLAVNM 257 +N D + + Sbjct: 202 VINVDFADVRTTL 214 >4XCQ-A nrPDB Length = 318 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 53/109 (48%), Gaps = 17/109 (15%) Query: 101 WAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYP 160 +A+ +Y +++ +++ +CD + ++ GGTGSG+ ++ ++ YP Sbjct: 70 YAQTYY---KQIIAQIMEKF----SSCDIV---IFVATMAGGTGSGITPPILGLAKQMYP 119 Query: 161 DRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDE-----TYCIDN 204 ++ V+P K ++ + E NA + ++ +T+E Y +DN Sbjct: 120 NKHFGFVGVLP--KATEDIDEHMNAIACWNDIMRSTNEGKDISIYLLDN 166 >3V3T-A nrPDB Length = 360 Score = 35.4 bits (80), Expect = 0.055, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 52/109 (47%), Gaps = 17/109 (15%) Query: 101 WAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYP 160 +A+ +Y +++ +++ +CD + ++ GG GSG+ ++ ++ YP Sbjct: 70 YAQTYY---KQIIAQIMEKF----SSCDIV---IFVATMAGGAGSGITPPILGLAKQMYP 119 Query: 161 DRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDE-----TYCIDN 204 ++ V+P K ++ + E NA + ++ +T+E Y +DN Sbjct: 120 NKHFGFVGVLP--KATEDIDEHMNAIACWNDIMRSTNEGKDISIYLLDN 166 >6G58-A nrPDB Length = 404 Score = 35.0 bits (79), Expect = 0.077, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 71/206 (34%), Gaps = 36/206 (17%) Query: 243 PGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAA 302 +N DL +A N F LH P + + Y L ++ + + + A Sbjct: 30 SAYMNVDLNAVASNFKVFSTLH---PNKTVMAVVKANAY-GLGSVKVARHLMENGATFFA 85 Query: 303 CDP--------RHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVC 354 HG +T + G + K++D+ + + + +W+ +K + Sbjct: 86 VATLDEAIELRMHG--ITAKILVLGVLPAKDIDKAIQH-RVALTVPSKQWLKEAIK-NIS 141 Query: 355 DIPPRGL--------KMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEM 406 + L M I ++ QE+ + I +Q+ + F H Sbjct: 142 GEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIE-IIQQYEQLVFEGVFTH---------- 190 Query: 407 EFTEAESNMNDLVSEYQQYQDATAEE 432 F A+ + +YQ+++D E Sbjct: 191 -FACADEPGDMTTEQYQRFKDMVNEA 215 >2VAP-A nrPDB Length = 364 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 4/98 (4%) Query: 161 DRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRT-LKLAT 219 T +VV P V + V NA + +L ++TD I NE L++I LKL Sbjct: 149 KIGALTVAVVTLPFVMEGKVRMKNAMEGLERLKQHTDTLVVIPNEKLFEIVPNMPLKL-- 206 Query: 220 PTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNM 257 + + ++ + G+ + G +N D + M Sbjct: 207 -AFKVADEVLINAVKGLVELITKDGLINVDFADVKAVM 243 >4XD9-B nrPDB Length = 221 Score = 33.4 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 21 WEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVPR 62 WE+ + + GI N G + ER + S ++VPR Sbjct: 113 WELFARKKGIGKYSNKPGAALADKERRKKLVYDEESGEWVPR 154 >6G4W-q nrPDB Length = 281 Score = 31.5 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 13/88 (14%) Query: 48 SVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNF------IFGQSGAGNNW 101 ++Y+E + KYV + ++D++ + A L+ P+N I +G ++ Sbjct: 15 ELFYDETEARKYVRNSRMIDIQ----TRMAGRALELLYLPENKPCYLLDIGCGTGLSGSY 70 Query: 102 AK--GHYTEGAELVDSVLD-VVRKECEN 126 GHY G ++ ++LD V +E E Sbjct: 71 LSDEGHYWVGLDISPAMLDEAVDREIEG 98 >6GI9-A nrPDB Length = 373 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 23/69 (33%), Gaps = 6/69 (8%) Query: 15 QIGAKFWEVISDEHG-IDPSGNYVGDSDLQLERISVYYNEASSHKY-----VPRAILVDL 68 +I + W H I P G + + + + PRA+ +D Sbjct: 97 RIAVQLWHTGRLSHSSIQPGGQAPVSASALNANTRTSLRDENGNAIRVDTTTPRALELDE 156 Query: 69 EPGTMDSVR 77 PG ++ R Sbjct: 157 IPGIVNDFR 165 >2VVG-A nrPDB Length = 350 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 47/131 (35%), Gaps = 20/131 (15%) Query: 73 MDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQG 132 +D+V G F F +GQ+GAG W G E + + + + Q Sbjct: 82 IDAVLEG-----FNSTIFAYGQTGAGKTWTMGGNKEEPGAIPNSFKHLFDAINSSSSNQN 136 Query: 133 FQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQL 192 F + +G+ L EE D I N + P D Y LS+H++ Sbjct: 137 FLV-----------IGSYL-ELYNEEIRDLIKNNTKL---PLKEDKTRGIYVDGLSMHRV 181 Query: 193 VENTDETYCID 203 + + +D Sbjct: 182 TTAAELSALMD 192 >5IM3-A nrPDB Length = 963 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 45/110 (40%), Gaps = 9/110 (8%) Query: 336 KNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRK--- 392 K + V + + + VA+ L + S+ I + +R++EQ TA F+R+ Sbjct: 36 KRNGTVVPYTDDKITVAITK---AFLAVEGGTAAASSRIHDTVRRLTEQVTATFKRRMPS 92 Query: 393 -AFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDD 441 +H E D++E + + +Y Y++A A E D Sbjct: 93 GGTIH--IEEIQDQVELALMRAGEQKVARDYVIYREARAAERKNAGAASD 140 >1BWR-A nrPDB Length = 233 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 25/58 (43%), Gaps = 2/58 (3%) Query: 29 GIDPSGNYVGDSDLQLERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFR 86 G+ P G + + R++ A + PRA +D +PG + S + + ++ Sbjct: 137 GLLPRGQHPNPLREKNRRVNELVRAALAGH--PRAHFLDADPGFVHSDGTISHHDMYD 192 >1MDA-H nrPDB Length = 368 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 18/37 (48%), Gaps = 3/37 (8%) Query: 78 SGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVD 114 SG + D I Q GA +N+A + G E++D Sbjct: 307 SGPISNGHDSDAIIAAQDGASDNYAN---SAGTEVLD 340 >5T6E-A nrPDB Length = 411 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 7/46 (15%) Query: 359 RGLKMSSTFIGNSTAIQELFKRISEQF----TAMFR---RKAFLHW 397 G + ++ + N T +QEL+ ++ + AMFR ++FLHW Sbjct: 40 EGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHW 85 >5HY3-B nrPDB Length = 60 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAE---EEGEMYEDD 440 + F+ W+ E M E T + ++ ++Y + A + ++ ++ E D Sbjct: 5 KVVFMGWFKNESMFTKEITMMKDDVQWATTQYAEVNKALVKAFIDDKKVCEVD 57 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.140 0.385 Lambda K H 0.267 0.0425 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,754,038 Number of Sequences: 36641 Number of extensions: 726705 Number of successful extensions: 2321 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 45 Number of HSP's that attempted gapping in prelim test: 2163 Number of HSP's gapped (non-prelim): 128 length of query: 450 length of database: 10,336,785 effective HSP length: 100 effective length of query: 350 effective length of database: 6,672,685 effective search space: 2335439750 effective search space used: 2335439750 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.1 bits)