BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9DC50 (612 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1XMD-A nrPDB 1283 0.0 1T7N-A nrPDB 315 4e-86 1S5O-A nrPDB 296 2e-80 1T1U-A nrPDB 263 1e-70 2FY4-A nrPDB 254 1e-67 2FYO-A nrPDB 241 9e-64 1LBZ-A nrPDB 31 1.4 6HIV-A2 nrPDB 30 3.1 5W94-A nrPDB 29 5.1 1UA4-A nrPDB 29 6.9 5FAJ-A nrPDB 29 7.0 4KXA-A nrPDB 28 9.8 >1XMD-A nrPDB Length = 612 Score = 1283 bits (3319), Expect = 0.0, Method: Compositional matrix adjust. Identities = 611/612 (99%), Positives = 612/612 (100%) Query: 1 MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE 60 MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE Sbjct: 1 MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE 60 Query: 61 GAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGT 120 GAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGT Sbjct: 61 GAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGT 120 Query: 121 QLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF 180 QLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF Sbjct: 121 QLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF 180 Query: 181 KTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAAL 240 KTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAAL Sbjct: 181 KTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAAL 240 Query: 241 TSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG 300 TSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG Sbjct: 241 TSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG 300 Query: 301 DPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVR 360 DPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMV+VNIAHYVDERVLETEGRWKGSEKVR Sbjct: 301 DPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVVVNIAHYVDERVLETEGRWKGSEKVR 360 Query: 361 DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFI 420 DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFI Sbjct: 361 DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFI 420 Query: 421 QLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQ 480 QLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQ Sbjct: 421 QLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQ 480 Query: 481 QKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV 540 QKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV Sbjct: 481 QKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV 540 Query: 541 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF 600 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF Sbjct: 541 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF 600 Query: 601 HDMIQLMNTAHL 612 HDMIQLMNTAHL Sbjct: 601 HDMIQLMNTAHL 612 >1T7N-A nrPDB Length = 618 Score = 315 bits (807), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 206/611 (33%), Positives = 316/611 (51%), Gaps = 38/611 (6%) Query: 16 YQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLER 73 +QD+LP LPVP L++SL YL++++P +E+E+ T+++V +FQ G G+RL + L R Sbjct: 23 HQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERR 82 Query: 74 ARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNL 133 A+ NWL EWWL AYL R P V + P QL + ++ L Sbjct: 83 AKKMENWLSEWWLKTAYLQFRQPV---VIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVL 139 Query: 134 NYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIA 193 ++ ++ E LPV G PL MNQ+ + S+C+VPG +DS++N+ K++ PTHI Sbjct: 140 DFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRP---PTHIT 196 Query: 194 VLCRGRAFVFDVLH-EGCLITPPELLRQLTYIHK---KCSNEPVGPSIAALTSEERTRWA 249 V+ + F DV H +G +T ++ QL I + + EPVG LTS R WA Sbjct: 197 VVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVG----ILTSNHRNTWA 252 Query: 250 KAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQ--VFEMLLGG----DPS 303 KA LI D N + IQ S+F ++ P + + Y +ML GG + Sbjct: 253 KAYNNLIK-DKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSG 311 Query: 304 VRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRD-- 361 RW DK+ I +G G +HA + +V + +V E K E VR Sbjct: 312 NRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYT-------KKPELVRSPM 364 Query: 362 --IPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTF 419 +P+P++L F + +I ND+ +AK DL I TF FGK K E L PD F Sbjct: 365 VPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAF 424 Query: 420 IQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLER 479 IQ+ALQLAYYR++G+ YE+A R F+ GRT+T+RS +++++ + + M D + ++ Sbjct: 425 IQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQK 484 Query: 480 QQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNF 539 + + +A H G+ FDRHLLGL L A E+ + +P++F D ++ + +F Sbjct: 485 VELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHF 541 Query: 540 VLSTSLV-GYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFH 598 LSTS V G P+V +GYG Y+ + + S++ SC ET+A ++ + Sbjct: 542 NLSTSQVPAKTDCVGFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEK 601 Query: 599 AFHDMIQLMNT 609 A DM L+ Sbjct: 602 ALLDMRTLLQN 612 >1S5O-A nrPDB Length = 616 Score = 296 bits (757), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 199/599 (33%), Positives = 308/599 (51%), Gaps = 40/599 (6%) Query: 29 EESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLERARGKRNWLEEWWL 86 ++SL YL++++P +E+E+ T+++V +FQ G G+RL + L RAR NWL EWWL Sbjct: 23 QQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWL 82 Query: 87 NVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQLLRREKLPV 146 AYL R P V + P QL + ++ L++ ++ E LPV Sbjct: 83 KTAYLQYRQPV---VIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPV 139 Query: 147 HKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL 206 G PL MNQ+ + S+C+VPG +D++ N+ KT+ PTHI V+ + F DV Sbjct: 140 EYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKP---PTHITVVHNYQFFELDVY 196 Query: 207 H-EGCLITPPELLRQLTYIHK---KCSNEPVGPSIAALTSEERTRWAKAREYLISLDPEN 262 H +G +T ++ QL I + + EPVG LTS R WAKA LI D N Sbjct: 197 HSDGTPLTADQIFVQLEKIWNSSLQTNKEPVG----ILTSNHRNSWAKAYNTLIK-DKVN 251 Query: 263 LTLLEKIQTSLFVYSIEDSSPHATPEEYSQ--VFEMLLGGDPSV----RWGDKSYNLISF 316 + IQ S+F ++ + P + + Y +ML GG + RW DK+ I Sbjct: 252 RDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVA 311 Query: 317 ANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRD----IPLPEELVFTV 372 +G G +HA + +V + YV E K E VR +P+P++L F + Sbjct: 312 EDGSCGLVYEHAAAEGPPIVTLLDYVIEYT-------KKPELVRSPMVPLPMPKKLRFNI 364 Query: 373 DEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAYYRLH 432 +I +D+ +AK DL I F FGK K E L PD FIQ+ALQLAYYR++ Sbjct: 365 TPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIY 424 Query: 433 GRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLEAFAKHNK 492 G+ YE+A R F+ GRT+T+RS +++++ + ++M D S + ++ + + +A H Sbjct: 425 GQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRG 484 Query: 493 MMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQ 552 G+ FDRHLLGL L A E+ + P++F D ++ + +F LSTS V + Sbjct: 485 YTDRAIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDTSYAIA---MHFHLSTSQVP-AKTD 540 Query: 553 GVVV--PMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHDMIQLMNT 609 V+ P+V +GYG Y+ + + S++ SC ET+A +L + A DM L+ + Sbjct: 541 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS 599 >1T1U-A nrPDB Length = 639 Score = 263 bits (673), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 184/607 (30%), Positives = 303/607 (49%), Gaps = 30/607 (4%) Query: 20 LPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLERARGK 77 LP LPVP L+++L YL+ ++ E++++K++ IV++F G G+ L +KLLER Sbjct: 22 LPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKT 81 Query: 78 RNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQ 137 NW+ E+WLN YL+ R+ +N + P F QL + ++ L+Y Sbjct: 82 ANWVSEYWLNDMYLNNRLALPVNSS---PAVIFARQHFQDTNDQLRFAACLISGVLSYKT 138 Query: 138 LLRREKLPVH----KSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIA 193 LL LP + PL M Q+ LFS+ ++PG T+D+++ + S P H+ Sbjct: 139 LLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVA--QKSSIMPEPEHVI 196 Query: 194 VLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVG-PSIAALTSEERTRWAKAR 252 V C + FV DV+ ++ +L QL I K SNE P I LTS+ R+ WAKAR Sbjct: 197 VACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKAR 256 Query: 253 EYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGGDPSV----RWGD 308 L+ D N L+ I+ + + + D + + ++L GG S+ RW D Sbjct: 257 TVLLK-DSTNRDSLDMIERCICLVCL-DGPGTGELSDTHRALQLLHGGGCSLNGANRWYD 314 Query: 309 KSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEEL 368 KS + +G G C+H+P+D +V+V ++ + ++ + + ++ V ++P P L Sbjct: 315 KSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRL 374 Query: 369 VFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAY 428 + + ++ + + + +L F ++GK K++ PD FIQ+ALQLAY Sbjct: 375 RWKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAY 434 Query: 429 YRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQD-----PSASLLERQQKM 483 YRL+ R YE+A R F GR + +RS T EA+ + Q+M D P++ L+ Q Sbjct: 435 YRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTA 494 Query: 484 LEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLST 543 ++A ++ M G D HLL L +A++ PE+F D + S FVLST Sbjct: 495 MQAQTEYTVM---AITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMS---NRFVLST 548 Query: 544 SLV-GYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHD 602 S V + + P+V NGYG Y+ + + SS+ SC ET + + + + + D Sbjct: 549 SQVPTTMEMFCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVD 608 Query: 603 MIQLMNT 609 M L ++ Sbjct: 609 MRDLCSS 615 >2FY4-A nrPDB Length = 612 Score = 254 bits (648), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 180/604 (29%), Positives = 298/604 (49%), Gaps = 27/604 (4%) Query: 17 QDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLERA 74 + LP LPVP L+++L YL+ ++ +E++++K++ IVQ+F G G+ L QKLLER Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69 Query: 75 RGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLN 134 NW+ E+WLN YL+ R+ L VN ++P + QL + ++ L+ Sbjct: 70 EKTANWVSEYWLNDMYLNNRL--ALPVNSSPAVIFARQHFPGTDD-QLRFAASLISGVLS 126 Query: 135 YWQLLRREKLPVH----KSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPT 190 Y LL +P + PL M Q+ LFS+ ++PG T+D+++ + S P Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184 Query: 191 HIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVG-PSIAALTSEERTRWA 249 H+ V C + FV DV+ ++ +L QL I K SN P I LTS+ R+ WA Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNAAARLPPIGLLTSDGRSEWA 244 Query: 250 KAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG----DPSVR 305 +AR L+ D N L+ I+ + + + D+ + + ++L GG + + R Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302 Query: 306 WGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLP 365 W DKS + +G G C+H+P+D +V+V ++ + + + E + +P P Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQPE---LVRSPMVPLPAP 359 Query: 366 EELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQ 425 L + +I ++ + + + +L F ++GK K++ PD FIQ+ALQ Sbjct: 360 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 419 Query: 426 LAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKML- 484 LA+YRLH R YE+A R F GR + +RS T EA+ + +++ D A++ ++ +L Sbjct: 420 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 479 Query: 485 -EAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLST 543 +A G D HLL L +A+ +PE+F D + S FVLST Sbjct: 480 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCAALPEMFMDETYLMS---NRFVLST 536 Query: 544 SLV-GYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHD 602 S V + P+V NGYG Y+ + + + SS+ SC T + K + + + D Sbjct: 537 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCAATSSSKFAKAVEESLID 596 Query: 603 MIQL 606 M L Sbjct: 597 MRDL 600 >2FYO-A nrPDB Length = 653 Score = 241 bits (614), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 180/606 (29%), Positives = 287/606 (47%), Gaps = 56/606 (9%) Query: 13 TFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLE 72 T YQDSLP LP+P LE+++K+YL + KP ++ ++++TE + + F+ G GK LH LL Sbjct: 37 TMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFETGVGKELHAHLLA 96 Query: 73 RARGKR--NWLEEWWLNVAYLDVRIPSQLNVN---FVGPCPHFEHYWPAREGTQLERGSM 127 + + + +++ W ++ YL R LN N P P E+ T L ++ Sbjct: 97 QDKQNKHTSYISGPWFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAV 155 Query: 128 MLWHNLNYWQLLRREKLPVHKSGNT--------------------------PLDMNQFRM 161 L LL E ++ S + PLDM+Q+ Sbjct: 156 RFLKTLQAG-LLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 214 Query: 162 LFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL-HEGCLITPPELLRQ 220 LF++ ++P RD + K H+ VL +G +VFDVL +G ++ P E+ Sbjct: 215 LFNSTRIPRPNRDELFTDTKAR-------HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAH 267 Query: 221 LTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIED 280 L YI S P P +A LTSE R WA+ R+ LI N L+K+ +++F ++D Sbjct: 268 LKYILSDSSPVPEFP-VAYLTSENRDVWAELRQKLIF--DGNEETLKKVDSAVFCLCLDD 324 Query: 281 SSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAH 340 ++ + +L GD + RW DKS+NLI +G +H+ D + ++ + Sbjct: 325 ----FPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFN 380 Query: 341 YVDERVLETEGRWKGSE--KVRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAA 398 V +T S+ E L F + + ++ AK + L I + Sbjct: 381 EVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDS 440 Query: 399 STFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSC 458 F GK+ K++ L PD QLA Q+A+ R +G+ YE+ T F HGRTET+R Sbjct: 441 IQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPA 500 Query: 459 TVEAVRWCQS-MQDPSA-SLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKE 516 ++ R ++ ++DPS S+ E Q M E H ++ K+ + G+GFDRHL L +A Sbjct: 501 SIFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATA 560 Query: 517 EGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQ-GVVVPMVHNGYGFFYHIRDDRFV 575 GL +PEL+ DP + + +LSTS + V G P+V +G+G Y + DD Sbjct: 561 RGLNLPELYLDPAYQQMNHN---ILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIG 617 Query: 576 VACSSW 581 SS+ Sbjct: 618 CNVSSY 623 >1LBZ-A nrPDB Length = 252 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 6/59 (10%) Query: 306 WGDKSYNLISFANGIFGCCCDHAP------YDAMVMVNIAHYVDERVLETEGRWKGSEK 358 +G + L FA+G F C D P YDA V IA +V E +G G++K Sbjct: 169 FGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKK 227 >6HIV-A2 nrPDB Length = 471 Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust. Identities = 14/59 (23%), Positives = 33/59 (55%) Query: 2 ENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE 60 E + KS++E ++Q+ L ++P P+ + + + + ++K E + + T V+ F+E Sbjct: 57 ERNMLKSMKEHYLRHQEELGAMPAPSRLKMIDESMRNIKRVVKERDEEATARAVEIFKE 115 >5W94-A nrPDB Length = 624 Score = 29.3 bits (64), Expect = 5.1, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 14/105 (13%) Query: 70 LLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMML 129 LL + R K W +W+LN+ Y++ LN F P P E T+L L Sbjct: 184 LLSQCREKSQW--KWFLNLCYVNYL----LNERF--PIP--EDALQELRSTELHTVGPEL 233 Query: 130 WHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRD 174 + W+L + + K GN +N+F+ F T K +T + Sbjct: 234 YA----WKLALEMVIQLCKDGNITDHLNEFKNFFDTNKQSLVTNE 274 >1UA4-A nrPDB Length = 455 Score = 28.9 bits (63), Expect = 6.9, Method: Compositional matrix adjust. Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 8/95 (8%) Query: 360 RDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTF 419 R+IP+ E FT DEK+ ++ + AS G+K +E L D Sbjct: 259 REIPVHLEFAFTPDEKVREEILNVLGMFYSVGLNEVELASIMEILGEKKLAKELLAHDPV 318 Query: 420 IQLALQLAYYRLHGRPGC--------CYETAMTRY 446 +A+ A +L + G Y A+T Y Sbjct: 319 DPIAVTEAMLKLAKKTGVKRIHFHTYGYYLALTEY 353 >5FAJ-A nrPDB Length = 410 Score = 28.9 bits (63), Expect = 7.0, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 11/80 (13%) Query: 223 YIHKKCSNEPVGPSIAALTS--EERTRWAKAREYL-----ISLDPENLTL----LEKIQT 271 + H C++EP PSIAA + E T +A+ R I+ P LTL + ++ Sbjct: 198 WSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRP 257 Query: 272 SLFVYSIEDSSPHATPEEYS 291 + +Y + S TP ++ Sbjct: 258 GIAMYGVSPSPEIGTPADFG 277 >4KXA-A nrPDB Length = 888 Score = 28.5 bits (62), Expect = 9.8, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 31 SLKKYLESVKPFANEDEYKKTEEIVQKF-QEGAGKRLHQKLLERARGKRNWLE------- 82 +L + + +PF E + + E K+ Q GAG++ +++LE + WL+ Sbjct: 813 NLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIR 872 Query: 83 EWWLNV 88 EW+ N+ Sbjct: 873 EWFFNL 878 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1XMD-A nrPDB 973 0.0 1T7N-A nrPDB 838 0.0 1T1U-A nrPDB 826 0.0 2FY4-A nrPDB 823 0.0 1S5O-A nrPDB 802 0.0 2FYO-A nrPDB 708 0.0 Sequences not found previously or not previously below threshold: 6HIV-A2 nrPDB 33 0.31 5CW3-A nrPDB 32 0.96 4DJE-A nrPDB 30 2.1 1K3V-A nrPDB 29 7.7 CONVERGED! >1XMD-A nrPDB Length = 612 Score = 973 bits (2516), Expect = 0.0, Method: Composition-based stats. Identities = 611/612 (99%), Positives = 612/612 (100%) Query: 1 MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE 60 MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE Sbjct: 1 MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE 60 Query: 61 GAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGT 120 GAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGT Sbjct: 61 GAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGT 120 Query: 121 QLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF 180 QLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF Sbjct: 121 QLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYF 180 Query: 181 KTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAAL 240 KTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAAL Sbjct: 181 KTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAAL 240 Query: 241 TSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG 300 TSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG Sbjct: 241 TSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG 300 Query: 301 DPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVR 360 DPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMV+VNIAHYVDERVLETEGRWKGSEKVR Sbjct: 301 DPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVVVNIAHYVDERVLETEGRWKGSEKVR 360 Query: 361 DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFI 420 DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFI Sbjct: 361 DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFI 420 Query: 421 QLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQ 480 QLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQ Sbjct: 421 QLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQ 480 Query: 481 QKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV 540 QKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV Sbjct: 481 QKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV 540 Query: 541 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF 600 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF Sbjct: 541 LSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF 600 Query: 601 HDMIQLMNTAHL 612 HDMIQLMNTAHL Sbjct: 601 HDMIQLMNTAHL 612 >1T7N-A nrPDB Length = 618 Score = 838 bits (2165), Expect = 0.0, Method: Composition-based stats. Identities = 203/609 (33%), Positives = 315/609 (51%), Gaps = 30/609 (4%) Query: 14 FQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLL 71 +QD+LP LPVP L++SL YL++++P +E+E+ T+++V +FQ G G+RL + L Sbjct: 21 MAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLE 80 Query: 72 ERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWH 131 RA+ NWL EWWL AYL R P V + P QL + ++ Sbjct: 81 RRAKKMENWLSEWWLKTAYLQFRQPV---VIYSSPGVILPKQDFVDLQGQLRFAAKLIEG 137 Query: 132 NLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTH 191 L++ ++ E LPV G PL MNQ+ + S+C+VPG +DS++N+ K++ PTH Sbjct: 138 VLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRP---PTH 194 Query: 192 IAVLCRGRAFVFDVLH-EGCLITPPELLRQLTYIHK---KCSNEPVGPSIAALTSEERTR 247 I V+ + F DV H +G +T ++ QL I + + EPVG LTS R Sbjct: 195 ITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVG----ILTSNHRNT 250 Query: 248 WAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQ--VFEMLLGG----D 301 WAKA LI D N + IQ S+F ++ P + + Y +ML GG + Sbjct: 251 WAKAYNNLIK-DKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFN 309 Query: 302 PSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRD 361 RW DK+ I +G G +HA + +V + +V E + E + Sbjct: 310 SGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPE---LVRSPMVP 366 Query: 362 IPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQ 421 +P+P++L F + +I ND+ +AK DL I TF FGK K E L PD FIQ Sbjct: 367 LPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQ 426 Query: 422 LALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQ 481 +ALQLAYYR++G+ YE+A R F+ GRT+T+RS +++++ + + M D + ++ + Sbjct: 427 VALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVE 486 Query: 482 KMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVL 541 + +A H G+ FDRHLLGL L A E+ + +P++F D ++ + +F L Sbjct: 487 LLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHFNL 543 Query: 542 STSLVG-YLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF 600 STS V G P+V +GYG Y+ + + S++ SC ET+A ++ + A Sbjct: 544 STSQVPAKTDCVGFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKAL 603 Query: 601 HDMIQLMNT 609 DM L+ Sbjct: 604 LDMRTLLQN 612 >1T1U-A nrPDB Length = 639 Score = 826 bits (2134), Expect = 0.0, Method: Composition-based stats. Identities = 183/604 (30%), Positives = 298/604 (49%), Gaps = 24/604 (3%) Query: 20 LPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLERARGK 77 LP LPVP L+++L YL+ ++ E++++K++ IV++F G G+ L +KLLER Sbjct: 22 LPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKT 81 Query: 78 RNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQ 137 NW+ E+WLN YL+ R+ +N P F QL + ++ L+Y Sbjct: 82 ANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFQDTNDQLRFAACLISGVLSYKT 138 Query: 138 LLRREKLPVH----KSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIA 193 LL LP + PL M Q+ LFS+ ++PG T+D+++ + S P H+ Sbjct: 139 LLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVA--QKSSIMPEPEHVI 196 Query: 194 VLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVG-PSIAALTSEERTRWAKAR 252 V C + FV DV+ ++ +L QL I K SNE P I LTS+ R+ WAKAR Sbjct: 197 VACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKAR 256 Query: 253 EYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGGDPS----VRWGD 308 L+ D N L+ I+ + + + D + + ++L GG S RW D Sbjct: 257 TVLLK-DSTNRDSLDMIERCICLVCL-DGPGTGELSDTHRALQLLHGGGCSLNGANRWYD 314 Query: 309 KSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEEL 368 KS + +G G C+H+P+D +V+V ++ + ++ + + ++ V ++P P L Sbjct: 315 KSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRL 374 Query: 369 VFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAY 428 + + ++ + + + +L F ++GK K++ PD FIQ+ALQLAY Sbjct: 375 RWKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAY 434 Query: 429 YRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLL--ERQQKMLEA 486 YRL+ R YE+A R F GR + +RS T EA+ + Q+M D A++ E+ Q + A Sbjct: 435 YRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTA 494 Query: 487 FAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLV 546 + G D HLL L +A++ PE+F D + S FVLSTS V Sbjct: 495 MQAQTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMS---NRFVLSTSQV 551 Query: 547 G-YLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHDMIQ 605 + + P+V NGYG Y+ + + SS+ SC ET + + + + + DM Sbjct: 552 PTTMEMFCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRD 611 Query: 606 LMNT 609 L ++ Sbjct: 612 LCSS 615 >2FY4-A nrPDB Length = 612 Score = 823 bits (2127), Expect = 0.0, Method: Composition-based stats. Identities = 179/606 (29%), Positives = 296/606 (48%), Gaps = 27/606 (4%) Query: 17 QDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLERA 74 + LP LPVP L+++L YL+ ++ +E++++K++ IVQ+F G G+ L QKLLER Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQ 69 Query: 75 RGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLN 134 NW+ E+WLN YL+ R+ +N P F QL + ++ L+ Sbjct: 70 EKTANWVSEYWLNDMYLNNRLALPVN---SSPAVIFARQHFPGTDDQLRFAASLISGVLS 126 Query: 135 YWQLLRREKLPVH----KSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPT 190 Y LL +P + PL M Q+ LFS+ ++PG T+D+++ + S P Sbjct: 127 YKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVA--QNSSIMPEPE 184 Query: 191 HIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVG-PSIAALTSEERTRWA 249 H+ V C + FV DV+ ++ +L QL I K SN P I LTS+ R+ WA Sbjct: 185 HVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNAAARLPPIGLLTSDGRSEWA 244 Query: 250 KAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGG----DPSVR 305 +AR L+ D N L+ I+ + + + D+ + + ++L GG + + R Sbjct: 245 EARTVLVK-DSTNRDSLDMIERCICLVCL-DAPGGVELSDTHRALQLLHGGGYSKNGANR 302 Query: 306 WGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLP 365 W DKS + +G G C+H+P+D +V+V ++ + + + E + +P P Sbjct: 303 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQPE---LVRSPMVPLPAP 359 Query: 366 EELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQ 425 L + +I ++ + + + +L F ++GK K++ PD FIQ+ALQ Sbjct: 360 RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ 419 Query: 426 LAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKML- 484 LA+YRLH R YE+A R F GR + +RS T EA+ + +++ D A++ ++ +L Sbjct: 420 LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL 479 Query: 485 -EAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLST 543 +A G D HLL L +A+ +PE+F D + S FVLST Sbjct: 480 KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCAALPEMFMDETYLMS---NRFVLST 536 Query: 544 SLVG-YLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHD 602 S V + P+V NGYG Y+ + + + SS+ SC T + K + + + D Sbjct: 537 SQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCAATSSSKFAKAVEESLID 596 Query: 603 MIQLMN 608 M L + Sbjct: 597 MRDLCS 602 >1S5O-A nrPDB Length = 616 Score = 802 bits (2071), Expect = 0.0, Method: Composition-based stats. Identities = 195/594 (32%), Positives = 304/594 (51%), Gaps = 30/594 (5%) Query: 29 EESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLERARGKRNWLEEWWL 86 ++SL YL++++P +E+E+ T+++V +FQ G G+RL + L RAR NWL EWWL Sbjct: 23 QQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWL 82 Query: 87 NVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQLLRREKLPV 146 AYL R P V + P QL + ++ L++ ++ E LPV Sbjct: 83 KTAYLQYRQPV---VIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPV 139 Query: 147 HKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL 206 G PL MNQ+ + S+C+VPG +D++ N+ KT+ PTHI V+ + F DV Sbjct: 140 EYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKP---PTHITVVHNYQFFELDVY 196 Query: 207 H-EGCLITPPELLRQLTYIHK---KCSNEPVGPSIAALTSEERTRWAKAREYLISLDPEN 262 H +G +T ++ QL I + + EPVG LTS R WAKA LI D N Sbjct: 197 HSDGTPLTADQIFVQLEKIWNSSLQTNKEPVG----ILTSNHRNSWAKAYNTLIK-DKVN 251 Query: 263 LTLLEKIQTSLFVYSIEDSSPHATPEEYSQ--VFEMLLGG----DPSVRWGDKSYNLISF 316 + IQ S+F ++ + P + + Y +ML GG + RW DK+ I Sbjct: 252 RDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVA 311 Query: 317 ANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEELVFTVDEKI 376 +G G +HA + +V + YV E + E + +P+P++L F + +I Sbjct: 312 EDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPE---LVRSPMVPLPMPKKLRFNITPEI 368 Query: 377 LNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPG 436 +D+ +AK DL I F FGK K E L PD FIQ+ALQLAYYR++G+ Sbjct: 369 KSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQAC 428 Query: 437 CCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLEAFAKHNKMMKD 496 YE+A R F+ GRT+T+RS +++++ + ++M D S + ++ + + +A H Sbjct: 429 ATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDR 488 Query: 497 CSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVG-YLRVQGVV 555 G+ FDRHLLGL L A E+ + P++F D ++ + +F LSTS V Sbjct: 489 AIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDTSYAIA---MHFHLSTSQVPAKTDCVMFF 545 Query: 556 VPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHDMIQLMNT 609 P+V +GYG Y+ + + S++ SC ET+A +L + A DM L+ + Sbjct: 546 GPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS 599 >2FYO-A nrPDB Length = 653 Score = 708 bits (1828), Expect = 0.0, Method: Composition-based stats. Identities = 182/633 (28%), Positives = 294/633 (46%), Gaps = 59/633 (9%) Query: 13 TFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLE 72 T YQDSLP LP+P LE+++K+YL + KP ++ ++++TE + + F+ G GK LH LL Sbjct: 37 TMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFETGVGKELHAHLLA 96 Query: 73 RARGKR--NWLEEWWLNVAYLDVRIPSQLNVN---FVGPCPHFEHYWPAREGTQLERGSM 127 + + + +++ W + YL R LN N P P E+ T L ++ Sbjct: 97 QDKQNKHTSYISGPWFD-MYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAV 155 Query: 128 MLWHNLNYWQLLRREKLPVHKSGNT--------------------------PLDMNQFRM 161 L LL E ++ S + PLDM+Q+ Sbjct: 156 RFLKTLQAG-LLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 214 Query: 162 LFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL-HEGCLITPPELLRQ 220 LF++ ++P RD + K H+ VL +G +VFDVL +G ++ P E+ Sbjct: 215 LFNSTRIPRPNRDELFTDTKAR-------HLLVLRKGHFYVFDVLDQDGNIVNPLEIQAH 267 Query: 221 LTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIED 280 L YI S P P +A LTSE R WA+ R+ LI N L+K+ +++F ++D Sbjct: 268 LKYILSDSSPVPEFP-VAYLTSENRDVWAELRQKLIF--DGNEETLKKVDSAVFCLCLDD 324 Query: 281 SSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAH 340 ++ + +L GD + RW DKS+NLI +G +H+ D + ++ + Sbjct: 325 ----FPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFN 380 Query: 341 YVDERVLETEGRWKGSEK--VRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAA 398 V +T S+ E L F + + ++ AK + L I + Sbjct: 381 EVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDS 440 Query: 399 STFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSC 458 F GK+ K++ L PD QLA Q+A+ R +G+ YE+ T F HGRTET+R Sbjct: 441 IQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPA 500 Query: 459 TVEAVRWCQS-MQDPSA-SLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKE 516 ++ R ++ ++DPS S+ E Q M E H ++ K+ + G+GFDRHL L +A Sbjct: 501 SIFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATA 560 Query: 517 EGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQ-GVVVPMVHNGYGFFYHIRDDRFV 575 GL +PEL+ DP + + +LSTS + V G P+V +G+G Y + DD Sbjct: 561 RGLNLPELYLDPAYQQMNHN---ILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIG 617 Query: 576 VACSSWRSCPETDAEKLVQMIFHAFHDMIQLMN 608 SS+ +A + + + D+ + Sbjct: 618 CNVSSYSG---RNAREFLHCVQKCLEDIFDALE 647 >6HIV-A2 nrPDB Length = 471 Score = 33.2 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 2 ENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEG 61 E + KS++E ++Q+ L ++P P+ + + + + ++K E + + T V+ F+ Sbjct: 57 ERNMLKSMKEHYLRHQEELGAMPAPSRLKMIDESMRNIKRVVKERDEEATARAVEIFK-- 114 Query: 62 AGKRLHQKLLE 72 +RL + + Sbjct: 115 --ERLKRGIYR 123 >5CW3-A nrPDB Length = 255 Score = 31.6 bits (70), Expect = 0.96, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 3/77 (3%) Query: 27 ALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLERARGKRNWL---EE 83 +E Y+ ++ + + ++ ++ F G K +L R K++ + E Sbjct: 10 KVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRVEISSE 69 Query: 84 WWLNVAYLDVRIPSQLN 100 L A R+ +LN Sbjct: 70 QLLKAAAEAERLTVELN 86 >4DJE-A nrPDB Length = 262 Score = 30.5 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 32/76 (42%), Gaps = 8/76 (10%) Query: 467 QSMQDPSASLLERQQKMLEAFAKHNK------MMKDCSHGKGFDRHLLGLLLIAKEE--G 518 ++M + + + E+ +K+ +H M K R + L+A + G Sbjct: 92 RAMINSTNAEREKVEKLFPLAVEHGAALIGLTMNKTGIPKDSDTRLAFAMELVAAADEFG 151 Query: 519 LPVPELFEDPLFSRSG 534 LP+ +L+ DPL + Sbjct: 152 LPMEDLYIDPLILPAN 167 >1K3V-A nrPDB Length = 579 Score = 28.6 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 16/42 (38%), Gaps = 2/42 (4%) Query: 21 PSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGA 62 P LP + + YL ++ ++++I Q G Sbjct: 199 PWLPTKPTQ--YRYYLSCIRNLNPPTYTGQSQQITDSIQTGL 238 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.128 0.330 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,188,123 Number of Sequences: 36641 Number of extensions: 809462 Number of successful extensions: 2237 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 15 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 2130 Number of HSP's gapped (non-prelim): 26 length of query: 612 length of database: 10,336,785 effective HSP length: 103 effective length of query: 509 effective length of database: 6,562,762 effective search space: 3340445858 effective search space used: 3340445858 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)