BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9CA40 (147 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6DBY-A nrPDB 302 3e-83 5LPG-A nrPDB 109 4e-25 1VK6-A nrPDB 51 2e-07 6EHH-A nrPDB 49 1e-06 6GLL-A nrPDB 47 3e-06 5ANS-A nrPDB 45 1e-05 5WS7-A nrPDB 45 2e-05 5MZF-A nrPDB 44 2e-05 5OTN-A nrPDB 43 6e-05 2QJT-B nrPDB 42 8e-05 5YGU-B nrPDB 39 6e-04 2QJO-A nrPDB 38 0.002 1VC9-A nrPDB 38 0.002 1SZ3-A nrPDB 38 0.002 5C8L-A nrPDB 37 0.003 3SHD-A nrPDB 36 0.005 3EEU-A nrPDB 36 0.006 3A6V-A nrPDB 36 0.006 5I8U-G nrPDB 36 0.008 4V14-A nrPDB 35 0.008 2B0V-A nrPDB 35 0.009 5LF8-A nrPDB 35 0.017 5CFI-A nrPDB 34 0.025 3I7U-A nrPDB 33 0.046 2DSC-A nrPDB 33 0.050 1GA7-A nrPDB 32 0.14 3N77-A nrPDB 31 0.18 3OGA-A nrPDB 31 0.20 2A6T-A nrPDB 31 0.21 1RYA-A nrPDB 31 0.23 5J3Y-B nrPDB 31 0.23 1VHG-A nrPDB 30 0.28 3HHJ-A nrPDB 30 0.32 2I8U-A nrPDB 30 0.40 6DT3-A nrPDB 30 0.42 3BPT-A nrPDB 28 1.5 5LON-A nrPDB 28 1.6 5LTU-A nrPDB 28 1.8 4ZBP-A nrPDB 28 1.9 2FVV-A nrPDB 28 1.9 4IJX-A nrPDB 27 3.7 3V7N-A nrPDB 27 3.7 1R67-A nrPDB 26 6.4 6ARG-A nrPDB 26 7.4 >6DBY-A nrPDB Length = 150 Score = 302 bits (774), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 147/147 (100%), Positives = 147/147 (100%) Query: 1 MSTGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEE 60 MSTGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEE Sbjct: 4 MSTGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEE 63 Query: 61 TGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE 120 TGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE Sbjct: 64 TGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE 123 Query: 121 NLPKPLFWPLEKLFGSGFNPFTHGGGD 147 NLPKPLFWPLEKLFGSGFNPFTHGGGD Sbjct: 124 NLPKPLFWPLEKLFGSGFNPFTHGGGD 150 >5LPG-A nrPDB Length = 164 Score = 109 bits (273), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 56/123 (45%), Positives = 78/123 (63%), Gaps = 5/123 (4%) Query: 22 ILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEA 81 +LLG+R+ S+G +F LPGGHLEFGE++EECA RE EE L ++ + +V N+ ++ Sbjct: 29 VLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKE 88 Query: 82 PTPSHYVSVSIRA-VLVDPSQEPKNMEPEKCEGWDWYDWENLP--KPLFWPLEKLFGSGF 138 HYV++ ++ V V EPKN+EPEK E W+W WE LP LFW L L G+ Sbjct: 89 NY--HYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGY 146 Query: 139 NPF 141 +PF Sbjct: 147 DPF 149 >1VK6-A nrPDB Length = 269 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 31/118 (26%), Positives = 61/118 (51%), Gaps = 12/118 (10%) Query: 8 PRVA--VVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 P++A ++V I +SILL + + N + G +E GE+ E+ AREVMEE+G+K+ Sbjct: 137 PQIAPCIIVAIRRDDSILLAQH-TRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKV 195 Query: 66 EKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLP 123 + ++ +T F ++ + +++DP + + +WY +++LP Sbjct: 196 KNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEA---------NWYRYDDLP 244 >6EHH-A nrPDB Length = 176 Score = 48.5 bits (114), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%) Query: 6 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 + R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE++EE+GL + Sbjct: 22 STSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLSV 81 Query: 66 EKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKP 125 + + + + F +P S V P+ E + M P+ W+ + +P Sbjct: 82 DTLHKVGHISFEFVGSPELMDVHIFSADHVHGTPT-ESEEMRPQ------WFQLDQIPFA 134 Query: 126 LFWP 129 WP Sbjct: 135 DMWP 138 >6GLL-A nrPDB Length = 182 Score = 47.0 bits (110), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 R+ +V +L +LLG ++ G +A GG ++ GE+ E+ A RE+ EE+GL ++ + Sbjct: 31 RLYTLVLVLQPQRVLLGMKKRGFGAGRWAGFGGKVQEGETIEDGARRELQEESGLTVDAL 90 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENLPK 124 V VF+ P + + D Q E M P C W+ + +P Sbjct: 91 H--KVGQIVFEFVGEPE---LMDVHVFCTDSIQGTPVESDEMRP--C----WFQLDQIPF 139 Query: 125 PLFWP 129 WP Sbjct: 140 KDMWP 144 >5ANS-A nrPDB Length = 175 Score = 45.1 bits (105), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 15/125 (12%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE+ EE+GL ++ + Sbjct: 24 RLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDAL 83 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENLPK 124 V VF+ P + + D Q E M P C W+ + +P Sbjct: 84 H--KVGQIVFEFVGEPE---LMDVHVFCTDSIQGTPVESDEMRP--C----WFQLDQIPF 132 Query: 125 PLFWP 129 WP Sbjct: 133 KDMWP 137 >5WS7-A nrPDB Length = 156 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 15/125 (12%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE+ EE+GL ++ + Sbjct: 5 RLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDAL 64 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENLPK 124 V VF+ P + + D Q E M P W+ + +P Sbjct: 65 H--KVGQIVFEFVGEPE---LMDVHVFATDSIQGTPVESDEMRPS------WFQLDQIPF 113 Query: 125 PLFWP 129 WP Sbjct: 114 KDMWP 118 >5MZF-A nrPDB Length = 176 Score = 43.9 bits (102), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 15/125 (12%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE+ EE+GL ++ + Sbjct: 25 RLYTLVLVLQPERVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELREESGLTVDTL 84 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENLPK 124 V +F+ P + + D Q E M P+ W+ + +P Sbjct: 85 H--KVGQIMFEFVGEPE---LMDVHIFCTDSVQGTPVESDEMRPQ------WFQLDQIPF 133 Query: 125 PLFWP 129 WP Sbjct: 134 TDMWP 138 >5OTN-A nrPDB Length = 159 Score = 42.7 bits (99), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 11/123 (8%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 ++ +V ++ +LLG ++ G + GG ++ GE+ E+ A RE++EE+GL ++ Sbjct: 8 KLLTLVLVVQPGRVLLGMKKRGFGAGKWNGFGGKVQTGETIEQAARRELLEESGLTVDT- 66 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSI-RAVLVDPS-QEPKNMEPEKCEGWDWYDWENLPKPL 126 L N+ E + + V I RA + E M P+ W+D + +P Sbjct: 67 --LHKIGNIKFEFIGETELMDVHIFRADNYEGEPAESDEMRPQ------WFDIDKIPFSQ 118 Query: 127 FWP 129 W Sbjct: 119 MWA 121 >2QJT-B nrPDB Length = 352 Score = 42.4 bits (98), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 34/61 (55%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMK 69 V V ++ + IL+ +R++ G +ALPGG LE E+ + RE+ EET + + + Sbjct: 209 VTVDALVIVNDHILMVQRKAHPGKDLWALPGGFLECDETIAQAIIRELFEETNINLTHEQ 268 Query: 70 L 70 L Sbjct: 269 L 269 >5YGU-B nrPDB Length = 168 Score = 39.3 bits (90), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 P V +V+ G ++ RR G ++ P G + GES E+ RE+ EE GL + Sbjct: 9 PNVGIVISNRQGQ-VMWARR---FGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKD 64 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQE 102 +++L T N + P V + V + Q+ Sbjct: 65 VRILASTRNWLR-YKLPKRLVRWDTKPVCIGQKQK 98 >2QJO-A nrPDB Length = 341 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 29/50 (58%) Query: 16 ILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 ++ +L+ RR++ G ALPGG ++ E+ E RE+ EET LK+ Sbjct: 210 VVQAGHVLMVRRQAKPGLGLIALPGGFIKQNETLVEGMLRELKEETRLKV 259 >1VC9-A nrPDB Length = 126 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/65 (43%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query: 13 VVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLT 72 VVF +LL R +G F P GH E GES EE A REV E+TG++ E + L Sbjct: 8 VVFNAKREVLLL---RDRMGFWVF--PKGHPEPGESLEEAAVREVWEQTGVRAEVLLPLY 62 Query: 73 VTNNV 77 T V Sbjct: 63 PTRYV 67 >1SZ3-A nrPDB Length = 159 Score = 37.7 bits (86), Expect = 0.002, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFA----LPGGHLEFGESFEECAAREVMEETGLK 64 R A VV + ILL + + G+ A +P G +E GE+ ++ A RE EETGL+ Sbjct: 14 RAAGVVLLNERGDILLVQEKGIPGHPEKAGLWHIPSGAVEDGENPQDAAVREACEETGLR 73 Query: 65 IEKMKLL 71 + +K L Sbjct: 74 VRPVKFL 80 >5C8L-A nrPDB Length = 182 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 8 PRVAVVVFIL-NGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIE 66 P A+++ +L NGN +++ + R ++ P G + E A RE++EETG + + Sbjct: 43 PGAAMMIPLLPNGNVVMIHQYRHAVKKVFLEFPAGKRDHNEETLLTAKRELLEETGYEAK 102 Query: 67 KMKLLTVTNNVF 78 K LT + V Sbjct: 103 DWKFLTTIHPVI 114 >3SHD-A nrPDB Length = 153 Score = 36.2 bits (82), Expect = 0.005, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 63/154 (40%), Gaps = 23/154 (14%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 P V V +++ L + G + + P GHLE E+ E AARE+ EETG+ + Sbjct: 4 PHVTVAC-VVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQP 62 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE------N 121 + + + + TP +I + P+Q P + + + C W E N Sbjct: 63 QHFIRMHQWIAPDK-TPFLRFLFAIELEQICPTQ-PHDSDIDCCR---WVSAEEILQASN 117 Query: 122 LPKPLFWPLEKLFGSG----------FN-PFTHG 144 L PL + + SG FN PFT G Sbjct: 118 LRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKG 151 >3EEU-A nrPDB Length = 153 Score = 36.2 bits (82), Expect = 0.006, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 7/69 (10%) Query: 1 MSTGEAIPRVAVVVFILNGNSILLGRR---RSSIGNSTFALPGGHLEFGESFEECAAREV 57 + G IP VA F+ IL+G+R S G F PGG +E GE+ EE ARE+ Sbjct: 16 IRKGHWIPVVAG--FLRKDGKILVGQRPENNSLAGQWEF--PGGKIENGETPEEALAREL 71 Query: 58 MEETGLKIE 66 EE G++ E Sbjct: 72 NEELGIEAE 80 >3A6V-A nrPDB Length = 129 Score = 36.2 bits (82), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNST-FALPGGHLEFGESFEECAAREVMEETGLKIEK 67 ++AV + N I + RR + + PGG +E GE+ E+ RE+ EE G+ + Sbjct: 5 QIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGETPEQAVVRELQEEVGITPQH 64 Query: 68 MKLL 71 L Sbjct: 65 FSLF 68 >5I8U-G nrPDB Length = 207 Score = 35.8 bits (81), Expect = 0.008, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEF-GESFEECAAREVMEETGLKIEKM 68 VA+V NGN ++ + R + G + LP G L+ GE AARE+ EE GL+ Sbjct: 46 VAIVAMDDNGNIPMVYQYRHTYGRRLWELPAGLLDVAGEPPHLTAARELREEVGLQASTW 105 Query: 69 KLL 71 ++L Sbjct: 106 QVL 108 >4V14-A nrPDB Length = 138 Score = 35.4 bits (80), Expect = 0.008, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Query: 7 IPRVAVVVFILNGNSILLGRRRSSIGNSTF-ALPGGHLEFGESFEECAAREVMEETGLKI 65 I VA ++F + + I + +R + F PGG +E GES E+ RE+ EE G+ + Sbjct: 10 IHIVAGIIFNSDQSEIFITKRPDHLHKGGFWEFPGGKVEAGESREQAMVRELEEEIGITV 69 Query: 66 EKMKLL 71 + + Sbjct: 70 TEQQAF 75 >2B0V-A nrPDB Length = 153 Score = 35.4 bits (80), Expect = 0.009, Method: Compositional matrix adjust. Identities = 21/55 (38%), Positives = 25/55 (45%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETG 62 P V V I + LL P GHLE GES + +REV+EETG Sbjct: 7 PNVTVAAVIEQDDKYLLVEEIPRGTAIKLNQPAGHLEPGESIIQACSREVLEETG 61 >5LF8-A nrPDB Length = 328 Score = 34.7 bits (78), Expect = 0.017, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 12 VVVFILNGNSILLGRRRS--SIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 V+ + ++LL RR S+ + + PGGH+E E + RE+ EE+GL + + Sbjct: 96 AVILQSSDKTVLLTRRARTLSVSPNLWVPPGGHVELEEELLDGGLRELWEESGLHLPQ 153 >5CFI-A nrPDB Length = 152 Score = 33.9 bits (76), Expect = 0.025, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 28 RSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLL----TVTNNVFKEAPT 83 ++S + + P G E ES E A RE +EETG+ +K KLL T+ NV + Sbjct: 36 KASYADKHWTPPKGLHENNESGLETAVRETLEETGINKDKYKLLNYQKTLKYNVKDKPKE 95 Query: 84 PSHYVSV 90 ++Y+++ Sbjct: 96 TTYYLAM 102 >3I7U-A nrPDB Length = 134 Score = 33.1 bits (74), Expect = 0.046, Method: Compositional matrix adjust. Identities = 17/34 (50%), Positives = 24/34 (70%) Query: 33 NSTFALPGGHLEFGESFEECAAREVMEETGLKIE 66 ++ ++ P G++E GE EE A REV EETG+K E Sbjct: 24 SNVWSFPKGNIEPGEKPEETAVREVWEETGVKGE 57 >2DSC-A nrPDB Length = 212 Score = 33.1 bits (74), Expect = 0.050, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 2 STGEAIPRVAVVVFILNGNSILLGRR-RSSIGNSTFALPGGHLEFGESFEECAAREVMEE 60 T + + + V+ L+ I+L ++ R +G P G ++ GE+ E A RE+ EE Sbjct: 59 QTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEE 118 Query: 61 TGLK 64 TG K Sbjct: 119 TGYK 122 >1GA7-A nrPDB Length = 209 Score = 31.6 bits (70), Expect = 0.14, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 21/32 (65%) Query: 38 LPGGHLEFGESFEECAAREVMEETGLKIEKMK 69 + G +E GES E+ A RE +EE GL +++ K Sbjct: 94 MVAGMIEEGESVEDVARREAIEEAGLIVKRTK 125 >3N77-A nrPDB Length = 144 Score = 31.2 bits (69), Expect = 0.18, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN--STFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R V I N LL + + G +AL GG +E GE EE RE+ EE G E Sbjct: 7 RTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELG---E 63 Query: 67 KMKLLTVTNNVFKEAPTPSHYVS 89 ++ L +T F++ Y Sbjct: 64 QLILSDITPWTFRDDIRIKTYAD 86 >3OGA-A nrPDB Length = 165 Score = 30.8 bits (68), Expect = 0.20, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN--STFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R V I N LL + + G +AL GG +E GE EE RE+ EE G E Sbjct: 28 RTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELG---E 84 Query: 67 KMKLLTVTNNVFKEAPTPSHYVS 89 ++ L +T F++ Y Sbjct: 85 QLILSDITPWTFRDDIRIKTYAD 107 >2A6T-A nrPDB Length = 271 Score = 30.8 bits (68), Expect = 0.21, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 32 GNSTFALPGGHLEFGESFEECAAREVMEETGL 63 +S + P G ++ ES +CA REV EETG Sbjct: 124 ASSGWGFPKGKIDKDESDVDCAIREVYEETGF 155 >1RYA-A nrPDB Length = 160 Score = 30.8 bits (68), Expect = 0.23, Method: Compositional matrix adjust. Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 10/119 (8%) Query: 5 EAIPRVAVVVFILNGN-SILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGL 63 + P V++ + N LLG+R + + +PGG ++ E+ E R M E GL Sbjct: 14 RSTPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGL 73 Query: 64 K--IEKMKLLTV----TNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDW 116 + I + V ++ F +HYV + R + S+E + E+ + + W Sbjct: 74 RLPITAGQFYGVWQHFYDDNFSGTDFTTHYVVLGFRFRV---SEEELLLPDEQHDDYRW 129 >5J3Y-B nrPDB Length = 242 Score = 30.8 bits (68), Expect = 0.23, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 32 GNSTFALPGGHLEFGESFEECAAREVMEETGL 63 +S + P G ++ ES +CA REV EETG Sbjct: 119 ASSGWGFPKGKIDKDESDVDCAIREVYEETGF 150 >1VHG-A nrPDB Length = 198 Score = 30.4 bits (67), Expect = 0.28, Method: Compositional matrix adjust. Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 27/129 (20%) Query: 11 AVVVFILNGNSILLGRRRSSIGNSTFAL--PGGHLEFGESFEECAAREVMEETGLKIEKM 68 ++V I++ + IL+ R ++G ++ L G ++ GES E A RE+ EE G + Sbjct: 52 VMIVPIVDDHLILI--REYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGFGANDL 109 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPL-- 126 L K + PS Y S + V+ +++ PE EG + P+PL Sbjct: 110 TFLK------KLSMAPS-YFSSKMNIVVA------QDLYPESLEG-------DEPEPLPQ 149 Query: 127 -FWPLEKLF 134 WPL + Sbjct: 150 VRWPLAHMM 158 >3HHJ-A nrPDB Length = 158 Score = 30.4 bits (67), Expect = 0.32, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 5/68 (7%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFAL---PGGHLEFGESFEECAAREVMEETGLKIE 66 V + N +LL +R G S L PGG +E GE+ E RE+ EE G+ ++ Sbjct: 31 VVACALLDQDNRVLLTQRPE--GKSLAGLWEFPGGKVEQGETPEASLIRELEEELGVHVQ 88 Query: 67 KMKLLTVT 74 L +T Sbjct: 89 ADNLFPLT 96 >2I8U-A nrPDB Length = 167 Score = 30.0 bits (66), Expect = 0.40, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 6 AIPRVAVVVFILNGN-SILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLK 64 + P V++ + N LLG+R + + +PGG ++ E+ E R M E GL+ Sbjct: 15 STPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLR 74 Query: 65 I 65 + Sbjct: 75 L 75 >6DT3-A nrPDB Length = 144 Score = 30.0 bits (66), Expect = 0.42, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN--STFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R V I N LL + + G +AL GG +E GE EE RE+ EE G E Sbjct: 7 RTIVCPLIENEGHYLLCKMAADRGVFPGQWALSGGGVEPGERIEEALRREIREELG---E 63 Query: 67 KMKLLTVTNNVFKEAPTPSHY 87 K+ L + F++ Y Sbjct: 64 KLILTHIAPWCFRDDTRVKTY 84 >3BPT-A nrPDB Length = 363 Score = 28.1 bits (61), Expect = 1.5, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 12/71 (16%) Query: 46 GESF--EECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVS----------IR 93 G SF E+ M T LKI +L+ ++ +E T + +S + +R Sbjct: 258 GSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVR 317 Query: 94 AVLVDPSQEPK 104 AVL+D Q PK Sbjct: 318 AVLIDKDQSPK 328 >5LON-A nrPDB Length = 281 Score = 28.1 bits (61), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 5 EAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLK 64 + IP +F + + ILL R I + ++ P G + E C REV EETG Sbjct: 100 KTIPVRGAAIFNDSLSKILLLR---GINSKHWSFPRGKIGKDEDDVACCIREVKEETGFD 156 Query: 65 I 65 + Sbjct: 157 L 157 >5LTU-A nrPDB Length = 180 Score = 27.7 bits (60), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 30/54 (55%) Query: 38 LPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVS 91 +PGG +E E A REV EE G+K + +LL + N ++ T + ++V+ Sbjct: 48 VPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGIFENQDRKHRTYVYVLTVT 101 >4ZBP-A nrPDB Length = 310 Score = 27.7 bits (60), Expect = 1.9, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 4/61 (6%) Query: 15 FILNGNS--ILLGRRRSSI--GNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKL 70 ++N N+ +L+ + RS + + LP G + GE AREV EETG+ + +++ Sbjct: 137 LVINKNTKEVLVVQERSGFFKDKNVWKLPTGVINEGEDIWTGVAREVEEETGIIADFVEV 196 Query: 71 L 71 L Sbjct: 197 L 197 >2FVV-A nrPDB Length = 194 Score = 27.7 bits (60), Expect = 1.9, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 38 LPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLV 97 +PGG +E E A REV EE G+K +L+ + N ++ T YV V I ++ Sbjct: 70 VPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRT---YVYVLIVTEVL 126 Query: 98 DPSQEPKNMEPEKCEGWDWYDWENLPKPLFW 128 + ++ N+ ++ +W+ E+ K L + Sbjct: 127 EDWEDSVNIGRKR----EWFKIEDAIKVLQY 153 >4IJX-A nrPDB Length = 155 Score = 26.9 bits (58), Expect = 3.7, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 29/55 (52%) Query: 17 LNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLL 71 ++ N+I ++S G + P GH+E GE E A R EE G++ ++ ++ Sbjct: 19 VDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRATQEEAGIEAGQLTII 73 >3V7N-A nrPDB Length = 487 Score = 26.9 bits (58), Expect = 3.7, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 9/71 (12%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMK 69 VA VV+ G RS+ +F +P G +F A + GL IEK+ Sbjct: 246 VAQVVYYFKG---YFAATRSNDERVSFTVPSG------NFGNVCAGHIARMMGLPIEKLV 296 Query: 70 LLTVTNNVFKE 80 + T N+V E Sbjct: 297 VATNENDVLDE 307 >1R67-A nrPDB Length = 190 Score = 25.8 bits (55), Expect = 6.4, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 38/105 (36%), Gaps = 27/105 (25%) Query: 3 TGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPG-------GHLEFGESFEECAAR 55 T + +A ++ N LL RR+ S A PG GH + GES E+ R Sbjct: 26 TADTRLHLAFSSWLFNAKGQLLVTRRAL---SKKAWPGVWTNSVCGHPQLGESNEDAVIR 82 Query: 56 EVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPS 100 E G++I TP + RA DPS Sbjct: 83 RCRYELGVEI-----------------TPPESIYPDFRARATDPS 110 >6ARG-A nrPDB Length = 399 Score = 25.8 bits (55), Expect = 7.4, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 33/91 (36%), Gaps = 15/91 (16%) Query: 45 FGESFEECA-----AREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIR-AVLVD 98 G EECA +RE +E ++ + +F E P + V V Sbjct: 162 MGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVT 221 Query: 99 PSQEPKNMEPEKCEGWDWYDWENLPKPLFWP 129 +EPKN+ PEK KP F P Sbjct: 222 QDEEPKNLNPEKLRAI---------KPAFIP 243 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6DBY-A nrPDB 220 2e-58 5LPG-A nrPDB 148 8e-37 6EHH-A nrPDB 141 8e-35 5MZF-A nrPDB 132 5e-32 6GLL-A nrPDB 132 6e-32 5ANS-A nrPDB 131 2e-31 5WS7-A nrPDB 129 5e-31 5OTN-A nrPDB 124 1e-29 1VK6-A nrPDB 113 3e-26 5YGU-B nrPDB 101 1e-22 2QJT-B nrPDB 81 2e-16 1SZ3-A nrPDB 76 5e-15 2QJO-A nrPDB 72 8e-14 1VC9-A nrPDB 67 3e-12 Sequences not found previously or not previously below threshold: 3SHD-A nrPDB 67 4e-12 2B0V-A nrPDB 61 1e-10 3HHJ-A nrPDB 57 3e-09 3EEU-A nrPDB 54 3e-08 4V14-A nrPDB 53 4e-08 3I7U-A nrPDB 53 5e-08 2RRK-A nrPDB 53 6e-08 2FVV-A nrPDB 50 3e-07 6DT3-A nrPDB 50 4e-07 1KTG-A nrPDB 50 4e-07 3OGA-A nrPDB 49 5e-07 3N77-A nrPDB 49 5e-07 2I8U-A nrPDB 49 6e-07 3A6V-A nrPDB 49 7e-07 1RYA-A nrPDB 49 7e-07 4ZBP-A nrPDB 49 9e-07 5LTU-A nrPDB 47 3e-06 5U7F-A nrPDB 47 4e-06 2DSC-A nrPDB 46 4e-06 3GZ5-A nrPDB 46 9e-06 5LF8-A nrPDB 45 1e-05 1VHG-A nrPDB 45 1e-05 5I8U-G nrPDB 42 9e-05 1GA7-A nrPDB 42 1e-04 5J3Y-B nrPDB 42 1e-04 2A6T-A nrPDB 42 1e-04 4IJX-A nrPDB 41 2e-04 5CFI-A nrPDB 40 4e-04 5LON-A nrPDB 39 6e-04 3HYQ-A nrPDB 39 6e-04 5C8L-A nrPDB 38 0.001 1QVJ-A nrPDB 35 0.010 1R67-A nrPDB 35 0.014 2A8R-A nrPDB 33 0.055 5AJ4-Bj nrPDB 32 0.081 3BHO-A nrPDB 31 0.24 5OOL-e nrPDB 31 0.25 3Q91-A nrPDB 30 0.41 6ARG-A nrPDB 30 0.43 1VRQ-A nrPDB 28 1.3 2GAG-A nrPDB 28 1.4 2CBU-A nrPDB 28 1.9 6ENZ-A nrPDB 27 2.0 3FDG-A nrPDB 27 3.6 5T3P-A nrPDB 27 4.4 5QHA-A nrPDB 27 4.4 1HXP-A nrPDB 26 4.7 5IDI-A nrPDB 26 5.6 >6DBY-A nrPDB Length = 150 Score = 220 bits (561), Expect = 2e-58, Method: Composition-based stats. Identities = 147/147 (100%), Positives = 147/147 (100%) Query: 1 MSTGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEE 60 MSTGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEE Sbjct: 4 MSTGEAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEE 63 Query: 61 TGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE 120 TGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE Sbjct: 64 TGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWE 123 Query: 121 NLPKPLFWPLEKLFGSGFNPFTHGGGD 147 NLPKPLFWPLEKLFGSGFNPFTHGGGD Sbjct: 124 NLPKPLFWPLEKLFGSGFNPFTHGGGD 150 >5LPG-A nrPDB Length = 164 Score = 148 bits (373), Expect = 8e-37, Method: Composition-based stats. Identities = 56/126 (44%), Positives = 78/126 (61%), Gaps = 5/126 (3%) Query: 19 GNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVF 78 +LLG+R+ S+G +F LPGGHLEFGE++EECA RE EE L ++ + +V N+ Sbjct: 26 PRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFI 85 Query: 79 KEAPTPSHYVSVSIRA-VLVDPSQEPKNMEPEKCEGWDWYDWENLP--KPLFWPLEKLFG 135 ++ HYV++ ++ V V EPKN+EPEK E W+W WE LP LFW L L Sbjct: 86 EKENY--HYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKE 143 Query: 136 SGFNPF 141 G++PF Sbjct: 144 QGYDPF 149 >6EHH-A nrPDB Length = 176 Score = 141 bits (356), Expect = 8e-35, Method: Composition-based stats. Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%) Query: 6 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 + R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE++EE+GL + Sbjct: 22 STSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLSV 81 Query: 66 EKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKP 125 + + + + F +P S V P+ E + M P+ W+ + +P Sbjct: 82 DTLHKVGHISFEFVGSPELMDVHIFSADHVHGTPT-ESEEMRPQ------WFQLDQIPFA 134 Query: 126 LFWP 129 WP Sbjct: 135 DMWP 138 >5MZF-A nrPDB Length = 176 Score = 132 bits (332), Expect = 5e-32, Method: Composition-based stats. Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 15/127 (11%) Query: 7 IPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE+ EE+GL ++ Sbjct: 23 TSRLYTLVLVLQPERVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELREESGLTVD 82 Query: 67 KMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENL 122 + V +F+ P + + D Q E M P+ W+ + + Sbjct: 83 TLH--KVGQIMFEFVGEPE---LMDVHIFCTDSVQGTPVESDEMRPQ------WFQLDQI 131 Query: 123 PKPLFWP 129 P WP Sbjct: 132 PFTDMWP 138 >6GLL-A nrPDB Length = 182 Score = 132 bits (332), Expect = 6e-32, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 15/126 (11%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 R+ +V +L +LLG ++ G +A GG ++ GE+ E+ A RE+ EE+GL ++ Sbjct: 30 SRLYTLVLVLQPQRVLLGMKKRGFGAGRWAGFGGKVQEGETIEDGARRELQEESGLTVDA 89 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENLP 123 + V VF+ P + + D Q E M P W+ + +P Sbjct: 90 LH--KVGQIVFEFVGEPE---LMDVHVFCTDSIQGTPVESDEMRP------CWFQLDQIP 138 Query: 124 KPLFWP 129 WP Sbjct: 139 FKDMWP 144 >5ANS-A nrPDB Length = 175 Score = 131 bits (328), Expect = 2e-31, Method: Composition-based stats. Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 15/126 (11%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE+ EE+GL ++ Sbjct: 23 SRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDA 82 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQ----EPKNMEPEKCEGWDWYDWENLP 123 + V VF+ P + + D Q E M P W+ + +P Sbjct: 83 LH--KVGQIVFEFVGEPE---LMDVHVFCTDSIQGTPVESDEMRP------CWFQLDQIP 131 Query: 124 KPLFWP 129 WP Sbjct: 132 FKDMWP 137 >5WS7-A nrPDB Length = 156 Score = 129 bits (323), Expect = 5e-31, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 7/122 (5%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 R+ +V +L +LLG ++ G + GG ++ GE+ E+ A RE+ EE+GL ++ Sbjct: 4 SRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDA 63 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLF 127 + + F P + ++ P E M P W+ + +P Sbjct: 64 LHKVGQIVFEFVGEPELMDVHVFATDSIQGTPV-ESDEMRP------SWFQLDQIPFKDM 116 Query: 128 WP 129 WP Sbjct: 117 WP 118 >5OTN-A nrPDB Length = 159 Score = 124 bits (311), Expect = 1e-29, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 7/123 (5%) Query: 7 IPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIE 66 ++ +V ++ +LLG ++ G + GG ++ GE+ E+ A RE++EE+GL ++ Sbjct: 6 TSKLLTLVLVVQPGRVLLGMKKRGFGAGKWNGFGGKVQTGETIEQAARRELLEESGLTVD 65 Query: 67 KMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPL 126 + + F +P E M P+ W+D + +P Sbjct: 66 TLHKIGNIKFEFIGETELMDVHIFRADNYEGEP-AESDEMRPQ------WFDIDKIPFSQ 118 Query: 127 FWP 129 W Sbjct: 119 MWA 121 >1VK6-A nrPDB Length = 269 Score = 113 bits (282), Expect = 3e-26, Method: Composition-based stats. Identities = 31/118 (26%), Positives = 61/118 (51%), Gaps = 12/118 (10%) Query: 8 PRVA--VVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 P++A ++V I +SILL + + N + G +E GE+ E+ AREVMEE+G+K+ Sbjct: 137 PQIAPCIIVAIRRDDSILLAQH-TRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKV 195 Query: 66 EKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLP 123 + ++ +T F ++ + +++DP + + +WY +++LP Sbjct: 196 KNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEA---------NWYRYDDLP 244 >5YGU-B nrPDB Length = 168 Score = 101 bits (252), Expect = 1e-22, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 P V +V+ G ++ RR G ++ P G + GES E+ RE+ EE GL + Sbjct: 9 PNVGIVISNRQGQ-VMWARR---FGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKD 64 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQE 102 +++L T N + P V + V + Q+ Sbjct: 65 VRILASTRNWLR-YKLPKRLVRWDTKPVCIGQKQK 98 >2QJT-B nrPDB Length = 352 Score = 80.6 bits (197), Expect = 2e-16, Method: Composition-based stats. Identities = 20/66 (30%), Positives = 34/66 (51%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMK 69 V V ++ + IL+ +R++ G +ALPGG LE E+ + RE+ EET + + + Sbjct: 209 VTVDALVIVNDHILMVQRKAHPGKDLWALPGGFLECDETIAQAIIRELFEETNINLTHEQ 268 Query: 70 LLTVTN 75 L Sbjct: 269 LAIAKR 274 >1SZ3-A nrPDB Length = 159 Score = 76.0 bits (185), Expect = 5e-15, Method: Composition-based stats. Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN----STFALPGGHLEFGESFEECAAREVMEETGLK 64 R A VV + ILL + + G+ + +P G +E GE+ ++ A RE EETGL+ Sbjct: 14 RAAGVVLLNERGDILLVQEKGIPGHPEKAGLWHIPSGAVEDGENPQDAAVREACEETGLR 73 Query: 65 IEKMKLLT 72 + +K L Sbjct: 74 VRPVKFLG 81 >2QJO-A nrPDB Length = 341 Score = 72.2 bits (175), Expect = 8e-14, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 30/56 (53%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 + ++ +L+ RR++ G ALPGG ++ E+ E RE+ EET LK+ Sbjct: 204 ITTDAVVVQAGHVLMVRRQAKPGLGLIALPGGFIKQNETLVEGMLRELKEETRLKV 259 >1VC9-A nrPDB Length = 126 Score = 66.8 bits (161), Expect = 3e-12, Method: Composition-based stats. Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMK 69 VVF +LL R +G F P GH E GES EE A REV E+TG++ E + Sbjct: 5 AGGVVFNAKREVLLL---RDRMGFWVF--PKGHPEPGESLEEAAVREVWEQTGVRAEVLL 59 Query: 70 LLTVTNNVFKE 80 L T V + Sbjct: 60 PLYPTRYVNPK 70 >3SHD-A nrPDB Length = 153 Score = 66.8 bits (161), Expect = 4e-12, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 42/112 (37%), Gaps = 7/112 (6%) Query: 12 VVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLL 71 V +++ L + G + + P GHLE E+ E AARE+ EETG+ + + Sbjct: 7 TVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFI 66 Query: 72 TVTNNVFK-EAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENL 122 + + + P ++ + + + + W E + Sbjct: 67 RMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSD------IDCCRWVSAEEI 112 >2B0V-A nrPDB Length = 153 Score = 61.4 bits (147), Expect = 1e-10, Method: Composition-based stats. Identities = 28/115 (24%), Positives = 41/115 (35%), Gaps = 4/115 (3%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 P V V I + LL P GHLE GES + +REV+EETG Sbjct: 7 PNVTVAAVIEQDDKYLLVEEIPRGTAIKLNQPAGHLEPGESIIQACSREVLEETGHSFLP 66 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENL 122 L + + T + S + V DP ++ W+ + + Sbjct: 67 EVLTGIYHWTCASNGTTYLRFTFSGQVVSFDPDRKLD----TGIVRAAWFSIDEI 117 >3HHJ-A nrPDB Length = 158 Score = 57.1 bits (136), Expect = 3e-09, Method: Composition-based stats. Identities = 29/128 (22%), Positives = 49/128 (38%), Gaps = 4/128 (3%) Query: 10 VAVVVFILNGNSILLGRR-RSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI--E 66 V + N +LL +R + PGG +E GE+ E RE+ EE G+ + + Sbjct: 31 VVACALLDQDNRVLLTQRPEGKSLAGLWEFPGGKVEQGETPEASLIRELEEELGVHVQAD 90 Query: 67 KMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPL 126 + LT ++ ++ V +E +N++ D Y KPL Sbjct: 91 NLFPLTFASHGYETFHLLMPLY-FCSHYKGVAQGREGQNLKWIFINDLDKYPMPEADKPL 149 Query: 127 FWPLEKLF 134 L+ F Sbjct: 150 VQVLKNFF 157 >3EEU-A nrPDB Length = 153 Score = 53.7 bits (127), Expect = 3e-08, Method: Composition-based stats. Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 4 GEAIPRVAVVVFILNGNSILLGRRRSSIG-NSTFALPGGHLEFGESFEECAAREVMEETG 62 G IP VA F+ IL+G+R + + PGG +E GE+ EE ARE+ EE G Sbjct: 19 GHWIPVVAG--FLRKDGKILVGQRPENNSLAGQWEFPGGKIENGETPEEALARELNEELG 76 Query: 63 LKIE 66 ++ E Sbjct: 77 IEAE 80 >4V14-A nrPDB Length = 138 Score = 53.3 bits (126), Expect = 4e-08, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%) Query: 10 VAVVVFILNGNSILLGRRRSS-IGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 VA ++F + + I + +R + PGG +E GES E+ RE+ EE G+ + + Sbjct: 13 VAGIIFNSDQSEIFITKRPDHLHKGGFWEFPGGKVEAGESREQAMVRELEEEIGITVTEQ 72 Query: 69 K 69 + Sbjct: 73 Q 73 >3I7U-A nrPDB Length = 134 Score = 52.9 bits (125), Expect = 5e-08, Method: Composition-based stats. Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Query: 18 NGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNV 77 +LL + S+ ++ P G++E GE EE A REV EETG+K E + + + Sbjct: 13 KDGEVLLIKTPSN----VWSFPKGNIEPGEKPEETAVREVWEETGVKGEILDYIGEIHYW 68 Query: 78 F 78 + Sbjct: 69 Y 69 >2RRK-A nrPDB Length = 140 Score = 52.5 bits (124), Expect = 6e-08, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 32/88 (36%), Gaps = 3/88 (3%) Query: 12 VVVFILNGNSILLGRRRS-SIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKL 70 V I ILL +R + S + GG +E ES + RE+ EE G++ + Sbjct: 12 VAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDESQRQALVRELREELGIEATVGEY 71 Query: 71 LTVTNNVFKEAPTPSHYVSVSIRAVLVD 98 + + + H + + Sbjct: 72 VASHQR--EVSGRIIHLHAWHVPDFHGT 97 >2FVV-A nrPDB Length = 194 Score = 50.2 bits (118), Expect = 3e-07, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 35/102 (34%), Gaps = 9/102 (8%) Query: 20 NSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFK 79 +LL + +PGG +E E A REV EE G+K +L+ + N Sbjct: 54 EEVLLVSSSRHP--DRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFEN--- 108 Query: 80 EAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWEN 121 + ++V E +W+ E+ Sbjct: 109 ----QERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWFKIED 146 >6DT3-A nrPDB Length = 144 Score = 49.8 bits (117), Expect = 4e-07, Method: Composition-based stats. Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN--STFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R V I N LL + + G +AL GG +E GE EE RE+ EE G E Sbjct: 7 RTIVCPLIENEGHYLLCKMAADRGVFPGQWALSGGGVEPGERIEEALRREIREELG---E 63 Query: 67 KMKLLTVTNNVFK 79 K+ L + F+ Sbjct: 64 KLILTHIAPWCFR 76 >1KTG-A nrPDB Length = 138 Score = 49.8 bits (117), Expect = 4e-07, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 37/114 (32%), Gaps = 7/114 (6%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIE--K 67 +V++ I ++S + P GH++ GE + A RE EE + E Sbjct: 6 AGLVIYRKLAGKIEFLLLQASYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLT 65 Query: 68 MKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWEN 121 + ++ P + D Q + W W + E+ Sbjct: 66 IHEDCHETLFYEAKGKPKSVKYWLAKLNNPDDVQLSHE-----HQNWKWCELED 114 >3OGA-A nrPDB Length = 165 Score = 49.4 bits (116), Expect = 5e-07, Method: Composition-based stats. Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN--STFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R V I N LL + + G +AL GG +E GE EE RE+ EE G E Sbjct: 28 RTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELG---E 84 Query: 67 KMKLLTVTNNVFKEAPTPSHYVS 89 ++ L +T F++ Y Sbjct: 85 QLILSDITPWTFRDDIRIKTYAD 107 >3N77-A nrPDB Length = 144 Score = 49.4 bits (116), Expect = 5e-07, Method: Composition-based stats. Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGN--STFALPGGHLEFGESFEECAAREVMEETGLKIE 66 R V I N LL + + G +AL GG +E GE EE RE+ EE G E Sbjct: 7 RTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELG---E 63 Query: 67 KMKLLTVTNNVFKEAPTPSHYVS 89 ++ L +T F++ Y Sbjct: 64 QLILSDITPWTFRDDIRIKTYAD 86 >2I8U-A nrPDB Length = 167 Score = 49.4 bits (116), Expect = 6e-07, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 6 AIPRVAVVVFI-LNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLK 64 + P V++ + + LLG+R + + +PGG ++ E+ E R M E GL+ Sbjct: 15 STPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLR 74 Query: 65 I 65 + Sbjct: 75 L 75 >3A6V-A nrPDB Length = 129 Score = 49.1 bits (115), Expect = 7e-07, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 9 RVAVVVFILNGNSILLGRRR-SSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEK 67 ++AV + N I + RR + + PGG +E GE+ E+ RE+ EE G+ + Sbjct: 5 QIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGETPEQAVVRELQEEVGITPQH 64 Query: 68 MKLLTVTNNVFK 79 L F Sbjct: 65 FSLFEKLEYEFP 76 >1RYA-A nrPDB Length = 160 Score = 49.1 bits (115), Expect = 7e-07, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 6 AIPRVAVVVFI-LNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLK 64 + P V++ + + LLG+R + + +PGG ++ E+ E R M E GL+ Sbjct: 15 STPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLR 74 Query: 65 I 65 + Sbjct: 75 L 75 >4ZBP-A nrPDB Length = 310 Score = 48.7 bits (114), Expect = 9e-07, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 46/114 (40%), Gaps = 6/114 (5%) Query: 10 VAVVVFILNGNSILLGRRRSSI--GNSTFALPGGHLEFGESFEECAAREVMEETGLK--- 64 +V N +L+ + RS + + LP G + GE AREV EETG+ Sbjct: 134 AGALVINKNTKEVLVVQERSGFFKDKNVWKLPTGVINEGEDIWTGVAREVEEETGIIADF 193 Query: 65 IEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYD 118 +E + + K+ +S R+ + Q+ + ++ + ++ D Sbjct: 194 VEVLAFRQSHKAILKKKTDMFFLCVLSPRSYDIT-EQKSEILQAKWMPIQEYVD 246 >5LTU-A nrPDB Length = 180 Score = 47.1 bits (110), Expect = 3e-06, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 36/104 (34%), Gaps = 9/104 (8%) Query: 18 NGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNV 77 + +LL + +PGG +E E A REV EE G+K + +LL + N Sbjct: 30 QEDEVLLVSSSRYP--DQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGIFEN- 86 Query: 78 FKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWEN 121 + + V E +W+ E+ Sbjct: 87 ------QDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVED 124 >5U7F-A nrPDB Length = 150 Score = 46.7 bits (109), Expect = 4e-06, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMK 69 + VV++ + +L+ +RR + G +E GE+ + A REV EE + + + Sbjct: 12 ILVVIYAQDTKRVLMLQRRDDPDF--WQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQ 69 Query: 70 L 70 L Sbjct: 70 L 70 >2DSC-A nrPDB Length = 212 Score = 46.4 bits (108), Expect = 4e-06, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 7/107 (6%) Query: 22 ILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEA 81 +L+ + R +G P G ++ GE+ E A RE+ EETG K + + + Sbjct: 80 VLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLS 139 Query: 82 PTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEG-WDWYDWENLPKPLF 127 H V+V+I +N P+ G ++ + +LPK Sbjct: 140 NCTIHIVTVTINGDD------AENARPKPKPGDGEFVEVISLPKNDL 180 >3GZ5-A nrPDB Length = 240 Score = 45.6 bits (106), Expect = 9e-06, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Query: 18 NGNSILLGRRRSSIGNSTFALPGGHLE--FGESFEECAAREVMEETGL 63 +LL +R + + LPGG ++ ES E+ R++ E+T + Sbjct: 35 QQLKVLLVQRSNHPFLGLWGLPGGFIDETCDESLEQTVLRKLAEKTAV 82 >5LF8-A nrPDB Length = 328 Score = 45.2 bits (105), Expect = 1e-05, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Query: 13 VVFILNGNSILLGRRRS--SIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 V+ + ++LL RR S+ + + PGGH+E E + RE+ EE+GL + Sbjct: 97 VILQSSDKTVLLTRRARTLSVSPNLWVPPGGHVELEEELLDGGLRELWEESGLHL 151 >1VHG-A nrPDB Length = 198 Score = 45.2 bits (105), Expect = 1e-05, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 45/123 (36%), Gaps = 5/123 (4%) Query: 7 IPRVAVVVFILNGNSILLGRRRS-SIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 R AV++ + + ++L R + + G ++ GES E A RE+ EE G Sbjct: 47 TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGFGA 106 Query: 66 EKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDW-YDWENLPK 124 + L + + + V + L S E EP W + + L Sbjct: 107 NDLTFLKKLSMAPSYFSSKMNIV---VAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLED 163 Query: 125 PLF 127 P F Sbjct: 164 PDF 166 >5I8U-G nrPDB Length = 207 Score = 42.1 bits (97), Expect = 9e-05, Method: Composition-based stats. Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 11/116 (9%) Query: 10 VAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEF-GESFEECAAREVMEETGLKIEKM 68 VA+V NGN ++ + R + G + LP G L+ GE AARE+ EE GL+ Sbjct: 46 VAIVAMDDNGNIPMVYQYRHTYGRRLWELPAGLLDVAGEPPHLTAARELREEVGLQASTW 105 Query: 69 KLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQE---PKNMEPEKCEGWDWYDWEN 121 + V + T + S+R L +E P+ + WY Sbjct: 106 Q-------VLVDLDTAPGFSDESVRVYLATGLREVGRPEAHHEQADMTMGWYPIAE 154 >1GA7-A nrPDB Length = 209 Score = 41.7 bits (96), Expect = 1e-04, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 34/93 (36%), Gaps = 10/93 (10%) Query: 34 STFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIR 93 + G +E GES E+ A RE +EE GL +++ K + S S+ + Sbjct: 90 WLLEMVAGMIEEGESVEDVARREAIEEAGLIVKRTKPVLS---FLASPGGTSERSSIMVG 146 Query: 94 AVLVDPSQ-------EPKNMEPEKCEGWDWYDW 119 V + E +++ Y W Sbjct: 147 EVDATTASGIHGLADENEDIRVHVVSREQAYQW 179 >5J3Y-B nrPDB Length = 242 Score = 41.7 bits (96), Expect = 1e-04, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 10/116 (8%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 R A+++ + +L+ ++S G + P G ++ ES +CA REV EETG Sbjct: 99 RGAIMLDMSMQQCVLVKGWKASSG---WGFPKGKIDKDESDVDCAIREVYEETGFDCSS- 154 Query: 69 KLLTVTNNVFKEAPTPSHYVS-VSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLP 123 + N F + V I + +D E + + + +W++ +LP Sbjct: 155 ---RINPNEFIDMTIRGQNVRLYIIPGISLDTRFESRTRK--EISKIEWHNLMDLP 205 >2A6T-A nrPDB Length = 271 Score = 41.7 bits (96), Expect = 1e-04, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 10/116 (8%) Query: 9 RVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 R A+++ + +L+ ++S G + P G ++ ES +CA REV EETG Sbjct: 104 RGAIMLDMSMQQCVLVKGWKASSG---WGFPKGKIDKDESDVDCAIREVYEETGFDCSS- 159 Query: 69 KLLTVTNNVFKEAPTPSHYVS-VSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLP 123 + N F + V I + +D E + + + +W++ +LP Sbjct: 160 ---RINPNEFIDMTIRGQNVRLYIIPGISLDTRFESRTRK--EISKIEWHNLMDLP 210 >4IJX-A nrPDB Length = 155 Score = 41.0 bits (94), Expect = 2e-04, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Query: 28 RSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLL----TVTNNVFKEAPT 83 ++S G + P GH+E GE E A R EE G++ ++ ++ N V + P Sbjct: 30 QASDGIHHWTPPKGHVEPGEDDLETALRATQEEAGIEAGQLTIIEGFKRELNYVARNKPK 89 Query: 84 PSHYVSVSIRAVLVD 98 Y ++ V+ Sbjct: 90 TVIYWLAEVKDYDVE 104 >5CFI-A nrPDB Length = 152 Score = 39.8 bits (91), Expect = 4e-04, Method: Composition-based stats. Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Query: 28 RSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTN----NVFKEAPT 83 ++S + + P G E ES E A RE +EETG+ +K KLL NV + Sbjct: 36 KASYADKHWTPPKGLHENNESGLETAVRETLEETGINKDKYKLLNYQKTLKYNVKDKPKE 95 Query: 84 PSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPL 126 ++Y+++ + + K G D NLP+ L Sbjct: 96 TTYYLAMLLN--NEENVILSDEHTDYKWIGSHESDTYNLPESL 136 >5LON-A nrPDB Length = 281 Score = 39.4 bits (90), Expect = 6e-04, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 48/124 (38%), Gaps = 14/124 (11%) Query: 5 EAIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLK 64 + IP +F + + ILL R I + ++ P G + E C REV EETG Sbjct: 100 KTIPVRGAAIFNDSLSKILLLR---GINSKHWSFPRGKIGKDEDDVACCIREVKEETGFD 156 Query: 65 IEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPE---KCEGWDWYDWEN 121 + + V + + + LV E +PE + + +W D++ Sbjct: 157 LTG--FIDADQYVERNMNGKNF------KIFLVKGVPEDFEFKPEHKNEIQAIEWKDFKK 208 Query: 122 LPKP 125 L K Sbjct: 209 LSKA 212 >3HYQ-A nrPDB Length = 184 Score = 39.4 bits (90), Expect = 6e-04, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 47/117 (40%), Gaps = 7/117 (5%) Query: 15 FILNGNSILLGRR----RSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKL 70 +L+ RR ++ G T ++ GH + GE+ EE R E G++I + Sbjct: 42 LFNEDGQLLVTRRSLSKKAWPGVWTNSV-CGHPQQGETTEEAIIRRCRFELGVEITDLTP 100 Query: 71 LTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLF 127 + + A P+ V + V + + E+ + W +++++ K L Sbjct: 101 VYP--HFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLL 155 >5C8L-A nrPDB Length = 182 Score = 38.3 bits (87), Expect = 0.001, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 37/89 (41%), Gaps = 3/89 (3%) Query: 8 PRVAVVVFILNGNSILLGRRRSSIGNSTF-ALPGGHLEFGESFEECAAREVMEETGLKIE 66 P A+++ +L ++++ + F P G + E A RE++EETG + + Sbjct: 43 PGAAMMIPLLPNGNVVMIHQYRHAVKKVFLEFPAGKRDHNEETLLTAKRELLEETGYEAK 102 Query: 67 KMKLLTVTNNVFKEAPTPSHYVSVSIRAV 95 K LT + V + H R + Sbjct: 103 DWKFLTTIHPVIGYSNE--HIDLYLARDL 129 >1QVJ-A nrPDB Length = 292 Score = 35.2 bits (79), Expect = 0.010, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 19/45 (42%) Query: 17 LNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEET 61 ++G IL +A+PGG ++ GE RE EE Sbjct: 133 VSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEA 177 >1R67-A nrPDB Length = 190 Score = 34.8 bits (78), Expect = 0.014, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 43/112 (38%), Gaps = 7/112 (6%) Query: 15 FILNGNSILLGRR----RSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKL 70 +L+ RR ++ G T ++ GH + GES E+ R E G++I + Sbjct: 39 LFNAKGQLLVTRRALSKKAWPGVWTNSV-CGHPQLGESNEDAVIRRCRYELGVEITPPES 97 Query: 71 LTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENL 122 + + A PS V + V + + ++ + W D ++ Sbjct: 98 IYP--DFRARATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADV 147 >2A8R-A nrPDB Length = 212 Score = 32.9 bits (73), Expect = 0.055, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 21/51 (41%), Gaps = 5/51 (9%) Query: 19 GNSILLGRRRSSIGNSTFALPGGHLEFGE-SFEECAAREVMEETGLKIEKM 68 +L+ R PGG ++ + S EE RE+ EE G + + Sbjct: 55 RRVLLMMMRFD----GRLGFPGGFVDTRDISLEEGLKRELEEELGPALATV 101 >5AJ4-Bj nrPDB Length = 279 Score = 32.1 bits (71), Expect = 0.081, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 3/66 (4%) Query: 17 LNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREV--MEETGLKIEKMKLLTVT 74 L+ N ILL R + + LP + GE+ + A R + + E ++ + + Sbjct: 153 LDRNLILLVREKLG-DQDIWMLPQSDWQPGETLRQTAERTLATLSENNMEAKFLGNAPCG 211 Query: 75 NNVFKE 80 + FK Sbjct: 212 HYKFKF 217 >3BHO-A nrPDB Length = 208 Score = 30.6 bits (67), Expect = 0.24, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 8/70 (11%) Query: 21 SILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVME----ETGLKIEKMKLLTVTNN 76 +LL + +G + F LPGG L GE E R + E + G+ + + + N Sbjct: 74 HVLLLQ----LGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNW 129 Query: 77 VFKEAPTPSH 86 P + Sbjct: 130 WRPNFEPPQY 139 >5OOL-e nrPDB Length = 279 Score = 30.6 bits (67), Expect = 0.25, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 17 LNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREV--MEETGLKIEKMKLLTVT 74 L+ N +LL R + + LP + GE+ A R + + E ++ + + Sbjct: 153 LDRNLVLLVREKFG-DQDVWILPQAEWQPGETLRGTAERTLATLSENNMEAKFLGNAPCG 211 Query: 75 NNVFKE 80 + FK Sbjct: 212 HYTFKF 217 >3Q91-A nrPDB Length = 218 Score = 29.8 bits (65), Expect = 0.41, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 14/34 (41%) Query: 44 EFGESFEECAAREVMEETGLKIEKMKLLTVTNNV 77 + G S EE A +E EE G + L V Sbjct: 106 QPGLSLEEVACKEAWEECGYHLAPSDLRRVATYW 139 >6ARG-A nrPDB Length = 399 Score = 29.8 bits (65), Expect = 0.43, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 6/71 (8%) Query: 46 GESFEECAA-----REVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRA-VLVDP 99 G EECA RE +E ++ + +F E P + V V Sbjct: 163 GLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQ 222 Query: 100 SQEPKNMEPEK 110 +EPKN+ PEK Sbjct: 223 DEEPKNLNPEK 233 >1VRQ-A nrPDB Length = 964 Score = 28.3 bits (61), Expect = 1.3, Method: Composition-based stats. Identities = 7/23 (30%), Positives = 11/23 (47%) Query: 34 STFALPGGHLEFGESFEECAARE 56 + P + + GES +E RE Sbjct: 593 GQWKRPWYYPQDGESMDEAVYRE 615 >2GAG-A nrPDB Length = 965 Score = 28.3 bits (61), Expect = 1.4, Method: Composition-based stats. Identities = 5/23 (21%), Positives = 11/23 (47%) Query: 34 STFALPGGHLEFGESFEECAARE 56 + P + + GE+ ++ RE Sbjct: 594 GQWKRPWYYPQAGETMDQAVYRE 616 >2CBU-A nrPDB Length = 468 Score = 27.9 bits (60), Expect = 1.9, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 90 VSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNP 140 S V DP K E+ WE +P+ ++W L+K+ +NP Sbjct: 317 YSGHLVKFDPDAPAKVSFVERDLPKTAMGWEIVPEGIYWILKKVKEE-YNP 366 >6ENZ-A nrPDB Length = 530 Score = 27.5 bits (59), Expect = 2.0, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%) Query: 35 TFALPGGHLEFGESFEECAAREVMEETGLKIEKM 68 P ++ GE F E A R +MEE LK + Sbjct: 43 VLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDV 76 >3FDG-A nrPDB Length = 355 Score = 26.7 bits (57), Expect = 3.6, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 15/39 (38%) Query: 27 RRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKI 65 R + G+ G + GE E R V E LKI Sbjct: 166 RPTVFGHGVPFRFPGSPDTGEGLTEAGRRLVAECNRLKI 204 >5T3P-A nrPDB Length = 236 Score = 26.7 bits (57), Expect = 4.4, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 27 RRSSIGNSTFALPGGHLEFGESFEEC-AAREVMEETGLKIEKMKLL 71 + PGG + + + A RE EE GL+ +++++ Sbjct: 63 EKLRRAPGEVCFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVV 108 >5QHA-A nrPDB Length = 196 Score = 26.7 bits (57), Expect = 4.4, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 27 RRSSIGNSTFALPGGHLEFGESFEEC-AAREVMEETGLKIEKMKLL 71 + PGG + + + A RE EE GL+ +++++ Sbjct: 49 EKLRRAPGEVCFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVV 94 >1HXP-A nrPDB Length = 348 Score = 26.3 bits (56), Expect = 4.7, Method: Composition-based stats. Identities = 11/84 (13%), Positives = 24/84 (28%), Gaps = 5/84 (5%) Query: 49 FEECAAREVMEETGLKIEKMKLLTVTNNV----FKEAPTPSHYVSVSIRAVLVDPSQEPK 104 + RE+ + + +E L V F+ P +V S Sbjct: 198 LVDYVQRELADGSRTVVETEHWLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLAL 257 Query: 105 NMEPEKCEGWDWYDWENLPKPLFW 128 ++ + + + P + W Sbjct: 258 ALKKLTSRYDNLFQC-SFPYSMGW 280 >5IDI-A nrPDB Length = 452 Score = 26.3 bits (56), Expect = 5.6, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 90 VSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNP 140 S V DP+ + E+ WE +P+ ++W L+ + +NP Sbjct: 293 YSGHMVKYDPNSPARVSFVERNLPKTAMGWEIVPEGIYWILKGVKEE-YNP 342 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.303 0.121 0.321 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,473,802 Number of Sequences: 36641 Number of extensions: 192678 Number of successful extensions: 643 Number of sequences better than 10.0: 64 Number of HSP's better than 10.0 without gapping: 99 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 527 Number of HSP's gapped (non-prelim): 119 length of query: 147 length of database: 10,336,785 effective HSP length: 88 effective length of query: 59 effective length of database: 7,112,377 effective search space: 419630243 effective search space used: 419630243 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 54 (25.5 bits)