BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9C168 (736 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1SY7-A nrPDB 1493 0.0 3TTT-A nrPDB 604 e-173 4BIM-A nrPDB 488 e-138 4B7A-A nrPDB 477 e-134 2IUF-A nrPDB 470 e-133 2IQF-A nrPDB 384 e-107 4QOP-A nrPDB 370 e-102 2J2M-A nrPDB 360 1e-99 1SI8-A nrPDB 359 2e-99 2ISA-A nrPDB 350 1e-96 1M7S-A nrPDB 349 2e-96 3HB6-A nrPDB 344 8e-95 4CAB-A nrPDB 338 6e-93 1QQW-A nrPDB 331 8e-91 4E37-A nrPDB 328 6e-90 2XQ1-A nrPDB 327 2e-89 5GKN-A nrPDB 325 5e-89 4B7G-A nrPDB 311 9e-85 1GWF-A nrPDB 310 2e-84 1A4E-A nrPDB 288 6e-78 1YE9-A nrPDB 276 2e-74 1YE9-E nrPDB 272 3e-73 3E4Y-A nrPDB 73 4e-13 2VRN-A nrPDB 35 0.17 3L18-A nrPDB 33 0.60 4TYM-A nrPDB 32 0.95 1YXA-A nrPDB 31 1.5 3KBG-A nrPDB 29 9.1 >1SY7-A nrPDB Length = 715 Score = 1493 bits (3866), Expect = 0.0, Method: Compositional matrix adjust. Identities = 715/715 (100%), Positives = 715/715 (100%) Query: 22 SKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRF 81 SKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRF Sbjct: 1 SKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRF 60 Query: 82 DHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSAD 141 DHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSAD Sbjct: 61 DHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSAD 120 Query: 142 TVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHN 201 TVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHN Sbjct: 121 TVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHN 180 Query: 202 NFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPEL 261 NFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPEL Sbjct: 181 NFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPEL 240 Query: 262 GVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDAT 321 GVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDAT Sbjct: 241 GVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDAT 300 Query: 322 KIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFD 381 KIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFD Sbjct: 301 KIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFD 360 Query: 382 TQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGY 441 TQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGY Sbjct: 361 TQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGY 420 Query: 442 LEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGR 501 LEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGR Sbjct: 421 LEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGR 480 Query: 502 MVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII 561 MVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII Sbjct: 481 MVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII 540 Query: 562 IADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIF 621 IADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIF Sbjct: 541 IADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIF 600 Query: 622 IPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHE 681 IPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHE Sbjct: 601 IPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHE 660 Query: 682 SYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY 736 SYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY Sbjct: 661 SYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY 715 >3TTT-A nrPDB Length = 753 Score = 604 bits (1557), Expect = e-173, Method: Compositional matrix adjust. Identities = 341/730 (46%), Positives = 438/730 (60%), Gaps = 51/730 (6%) Query: 15 ALTSAPSSKKVDDLKNEFKETDKSAR-------LTTDYGVKQTTADDWLRIVSDDKIGPS 67 A +AP S K D +NE + + R LTT+ GV+ + LR S GP+ Sbjct: 47 AQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSR---GPT 103 Query: 68 LLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVF 127 LLED RE+I FDHERIPER+VHARGS A G F+ Y+S SD+T A L+D ++ TPVF Sbjct: 104 LLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVF 163 Query: 128 VRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKP 187 VRFSTV G GSADTVRD+RGFA KFYTEEG +DLVGNN P+FFIQDA KFPD +HA KP Sbjct: 164 VRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKP 223 Query: 188 EPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQ 247 EPH +PQ QSAH+ FWD+ E H WAMSDR IPRS R M+GFG++T+ LINA+ Sbjct: 224 EPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAE 283 Query: 248 GKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAE 307 GK FV+FHW P G SLVWDEA KL G+DPDFHR++LWEAIE G +P+++ G Q I E Sbjct: 284 GKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPE 343 Query: 308 EDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFS 367 EDE KFDFD+LD TK+ PE+LVPV+ +G+M LNRNPD FF + EQ AF H+V G+ F+ Sbjct: 344 EDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFT 403 Query: 368 DDPLLQGRNFSYFDTQISRL-GVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPN 426 +DPLLQGR +SY DTQISRL G NF E+PINRP CP NF RDG R I NY PN Sbjct: 404 NDPLLQGRLYSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPN 463 Query: 427 RF-DACP---PASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHM 482 D P P K GG+ Y ++V G K R RS F E++S +LF+ S +P E++H+ Sbjct: 464 SINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHI 523 Query: 483 INAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMVGGEAP------TTTNHPNHGR 536 ++ F FEL P + R+V +LA IDL LAQ +A+ +G E T N + Sbjct: 524 VDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIELTDDQLNITPPPDVNGLK 583 Query: 537 KTINLSQTEFPPATPTIKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVT 596 K +LS P +K R VAI++ D + A A+ A ++ R +VT Sbjct: 584 KDPSLSLYAIPDG--DVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVT 641 Query: 597 AANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATG 656 A +G+ + G S VDA+ +P G A ++ NG A +++ EA+ HLK I G Sbjct: 642 ADDGTVLPIAATFAGAPSLTVDAVIVPCGNIA--DIADNGDANYYLMEAYKHLKPIALAG 699 Query: 657 EAVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAG-FLGEFFY 715 +A A + ++ + E G+V A A G F+ E Sbjct: 700 DARKFKAT------IKIADQGE----EGIVE---------------ADSADGSFMDELLT 734 Query: 716 AIAQHRNWDR 725 +A HR W R Sbjct: 735 LMAAHRVWSR 744 >4BIM-A nrPDB Length = 746 Score = 488 bits (1257), Expect = e-138, Method: Compositional matrix adjust. Identities = 247/543 (45%), Positives = 347/543 (63%), Gaps = 14/543 (2%) Query: 27 DLKNEFKET---DKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDH 83 D + KE D +TTD+G ++ + + + G +LLED R+++ FDH Sbjct: 65 DARQRLKEVEVDDNGQFMTTDFG---GNIEEQFSLKAGGR-GSTLLEDFIFRQKLQHFDH 120 Query: 84 ERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTV 143 ERIPERVVHARG+GA G F Y S++T A L ++TPVFVRFSTV GSRGSADT Sbjct: 121 ERIPERVVHARGAGAHGIFTSYGDWSNITAASFLGAKDKQTPVFVRFSTVAGSRGSADTA 180 Query: 144 RDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNF 203 RDV GFA +FYT+EGN+D+VGNNIPVFFIQDAI+FPD+IH+ KP P NEVPQA +AH++ Sbjct: 181 RDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIRFPDLIHSVKPSPDNEVPQAATAHDSA 240 Query: 204 WDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGV 263 WDF + A H WAMS IPRS R M GFG++T+ L+ GK VK+HW + G Sbjct: 241 WDFFSSQPSALHTLFWAMSGNGIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGK 300 Query: 264 HSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKI 323 +LVW+EA LAG++ DFHR+DLW+AIE+G P W+ +Q I E+ + FD+LD TK Sbjct: 301 AALVWEEAQVLAGKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKF 360 Query: 324 WPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQ 383 PE+ P++ +GEM LNRNP +F +TEQI+F H+V G+ F++DPLLQGR +SY DTQ Sbjct: 361 LPEEFAPLQVLGEMTLNRNPMNYFAETEQISFQPGHIVRGVDFTEDPLLQGRLYSYLDTQ 420 Query: 384 ISR-LGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPA----SLKE 438 ++R G NF++LPINRPV V N +RDG + I + +Y P+ + PA ++ Sbjct: 421 LNRHRGPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNIHHYSPSYLNKGYPAQANQTVGR 480 Query: 439 GGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVV 498 G + + +G+ R SA F +H++Q +LF+NS++P+E+Q +INA FE H + V Sbjct: 481 GFFTTPGRTASGVLNRELSATFDDHYTQPRLFFNSLTPVEQQFVINAIRFEASHVTNEQV 540 Query: 499 YGRMVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRV 558 ++++L I +A+ +A +G EAP P + + + F + PTI + RV Sbjct: 541 KKNVLEQLNKISNDVAKRVAVALGLEAPQPD--PTYYHNNVTRGVSIFNESLPTIATLRV 598 Query: 559 AII 561 ++ Sbjct: 599 GVL 601 >4B7A-A nrPDB Length = 719 Score = 477 bits (1227), Expect = e-134, Method: Compositional matrix adjust. Identities = 267/653 (40%), Positives = 372/653 (56%), Gaps = 29/653 (4%) Query: 32 FKETDKSARLTTDYG---VKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPE 88 ++ D + LT+D G QT+ +R GP+LLED R++I FDHER+PE Sbjct: 47 YEVDDSTGYLTSDVGGPIQDQTSLKAGIR-------GPTLLEDFMFRQKIQHFDHERVPE 99 Query: 89 RVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRG 148 R VHARG+GA G F Y S++T A L T ++TPVFVRFSTV GSRGSADT RDV G Sbjct: 100 RAVHARGAGAHGTFTSYADWSNITAASFLNATGKQTPVFVRFSTVAGSRGSADTARDVHG 159 Query: 149 FAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQF 208 FA +FYT+EGN+D+VGNNIPVFFIQDAI+FPD+IH+ KP P NE+PQA +AH++ WDF Sbjct: 160 FATRFYTDEGNFDIVGNNIPVFFIQDAIQFPDLIHSVKPRPDNEIPQAATAHDSAWDFFS 219 Query: 209 NHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVW 268 H WAMS IPRS R M GFGV+T+ + G +K+H+ G SLVW Sbjct: 220 QQPSTMHTLFWAMSGHGIPRSYRHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVW 279 Query: 269 DEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDL 328 +EA L+G++ DFHR+DLW+AIE+G P+W +Q + E F FD+LD TKI PE+ Sbjct: 280 EEAQVLSGKNADFHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEY 339 Query: 329 VPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL- 387 P+ +G ++L+RNP +F +TEQ+ F H+V GI F++DPLLQGR FSY DTQ++R Sbjct: 340 APLTKLGLLKLDRNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYLDTQLNRNG 399 Query: 388 GVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKE----GGYLE 443 G NF++LPIN P P+ N NRDGA + I R Y PN ++ P + G + Sbjct: 400 GPNFEQLPINMPRVPIHNNNRDGAGQMFIHRNKYPYTPNTLNSGYPRQANQNAGRGFFTA 459 Query: 444 YAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMV 503 + +G R S F +H+SQ +LF+NS++P+E+Q ++NA FE+ + V ++ Sbjct: 460 PGRTASGALVREVSPTFNDHWSQPRLFFNSLTPVEQQFLVNAMRFEISLVKSEEVKKNVL 519 Query: 504 QRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAIIIA 563 +L + +A +A +G AP + H KT +S P PTIK+ RV I+A Sbjct: 520 TQLNRVSHDVAVRVAAAIGLGAPDADDTYYHNNKTAGVSIVGSGP-LPTIKTLRVG-ILA 577 Query: 564 DGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIFIP 623 ++ A D A + + LV+ + T +T D + + Sbjct: 578 TTSESSALDQAAQLRTRLEKDGLVVTVVAETLREGVDQTYSTAD------ATGFDGVVVV 631 Query: 624 GGA------KAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQ 670 GA A+ L GR L +A+ K +G G V A +P+ Sbjct: 632 DGAAALFASTASSPLFPTGRPLQIFVDAYRWGKPVGVCGGKSSEVLDAADVPE 684 >2IUF-A nrPDB Length = 688 Score = 470 bits (1210), Expect = e-133, Method: Compositional matrix adjust. Identities = 281/718 (39%), Positives = 391/718 (54%), Gaps = 72/718 (10%) Query: 30 NEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPER 89 ++F D+ LT++ G + +S + G +LL+D RE+I RFDHER+PER Sbjct: 5 SQFYLNDQDVYLTSNVGGPIQDENS----LSAGQRGATLLQDFIFREKIQRFDHERVPER 60 Query: 90 VVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGF 149 VHARG+GA G F Y S+LT A L+ +ETP+F RFSTV GSRGSADT RDV GF Sbjct: 61 AVHARGTGAHGTFTSYGDWSNLTAASFLSAEGKETPMFTRFSTVAGSRGSADTARDVHGF 120 Query: 150 AVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFN 209 A +FYT+EGN+D+VGNNIPVFFIQDAI FPD+IHA KP N++PQA +AH++ WDF Sbjct: 121 ATRFYTDEGNFDIVGNNIPVFFIQDAILFPDLIHAVKPRGDNQIPQAATAHDSAWDFFSQ 180 Query: 210 HTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWD 269 H WAM+ IPRS R + GFGV+T+ L+ GK VKFHW G S VW+ Sbjct: 181 QPSVLHTLLWAMAGHGIPRSFRHVNGFGVHTFRLVTDDGKTKLVKFHWKGLQGKASFVWE 240 Query: 270 EALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLV 329 EA + AG++ DF R+DL+++I+ G +P+W+ G+Q + E+D+ KF FD+LD TKI PE+LV Sbjct: 241 EAQQTAGKNADFMRQDLFQSIQAGRFPEWELGVQIMQEQDQLKFGFDLLDPTKIVPEELV 300 Query: 330 PVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLG- 388 PV +G+M+LNRNP +F +TEQ+ F H+V G+ F++DPLLQGR FSY DTQ++R G Sbjct: 301 PVTILGKMQLNRNPMNYFAETEQVMFQPGHIVRGVDFTEDPLLQGRLFSYLDTQLNRHGG 360 Query: 389 VNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKE---GGYLEYA 445 NF++LPINRP P+ N NRDGA + I Y PN + P E G+ Sbjct: 361 PNFEQLPINRPRAPIHNNNRDGAGQMFIPLDPNAYSPNTENKGSPKQANETVGKGFFTAP 420 Query: 446 QKVA-GIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQ 504 ++ A G R S F+ ++SQ +LF+NS+ +K+ +++A FE + VV ++ Sbjct: 421 ERTASGKLQRTLSTTFENNWSQPRLFWNSLVNAQKEFIVDAMRFETSNVSSSVVRDDVII 480 Query: 505 RLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII--- 561 +L I LA +A +G EAP + H T ++ F + +V ++ Sbjct: 481 QLNRISDNLATRVASAIGVEAPKPNSSFYHDNTTAHIG--AFGEKLAKLDGLKVGLLASV 538 Query: 562 -----IADGY---------------------DNVAYDAAYAAISANQAIPLVIGPRRSKV 595 IA G +NV D Y+A A Q +V+ + Sbjct: 539 NKPASIAQGAKLQVALSSVGVDVVVVAERMANNV--DETYSASDAVQFDAVVVADGAEGL 596 Query: 596 TAANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGAT 655 A+ TV+P A TL GR L+ + +AF K +GA Sbjct: 597 FGADSFTVEPS------------------AGSGASTLYPAGRPLNILLDAFRFGKTVGAL 638 Query: 656 GEAVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAGFLGEF 713 G D AL +SSE + GV T K ++F +K FL F Sbjct: 639 GSGSD------ALESGQISSERQ-----GVYTGKNAG-DAFAKDIKSGLSTFKFLDRF 684 >2IQF-A nrPDB Length = 505 Score = 384 bits (987), Expect = e-107, Method: Compositional matrix adjust. Identities = 205/483 (42%), Positives = 290/483 (60%), Gaps = 13/483 (2%) Query: 47 VKQTTA------DDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFG 100 VKQTTA DD +++ GP LL+ + E++ FD ERIPERVVHA+GSGA+G Sbjct: 6 VKQTTAFGAPVWDD-NNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGSGAYG 64 Query: 101 KFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNW 160 F V + + T A + + ++T F RFSTV G RGSAD VRD RGFA+K+YTEEGNW Sbjct: 65 TFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYYTEEGNW 124 Query: 161 DLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWA 220 DLVGNN PVFFI+DAIKFPD IH K +P +P H+ WDF N E+ + TW Sbjct: 125 DLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPN----HDMVWDFWSNVPESLYQVTWV 180 Query: 221 MSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPD 280 MSDR IP+S R M GFG +T++LINA+G+R +VKFH+ GV L +EA ++ DPD Sbjct: 181 MSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEIRKHDPD 240 Query: 281 FHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELN 340 +++DL++AI G YPKWK IQ + EED K+ F D TKIW P+ +G +ELN Sbjct: 241 SNQRDLFDAIARGDYPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYTQDYPLMEVGIVELN 300 Query: 341 RNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPV 400 +NP+ +F + EQ AF ++VV GIG+S D +LQGR FSY DT RLGVN+ ++P+N+P Sbjct: 301 KNPENYFAEVEQAAFTPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQIPVNKPR 360 Query: 401 CPVMNFNRDGAMRHTISRGTVNYYPNRFDACPP-ASLKEGGY-LEYAQKVAGIKARARSA 458 CP + +RDG M++ NY P+ S ++ + L + +K + A Sbjct: 361 CPFHSSSRDGYMQNGYYGSLQNYTPSSLPGYKEDKSARDPKFNLAHIEKEFEVWNWDYRA 420 Query: 459 KFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIA 518 ++++Q +Y S+ EK+ + + G L H + + ++ D A+ + Sbjct: 421 DDSDYYTQPGDYYRSLPADEKERLHDTIGESLAHVTHKEIVDKQLEHFKKADPKYAEGVK 480 Query: 519 EMV 521 + + Sbjct: 481 KAL 483 >4QOP-A nrPDB Length = 491 Score = 370 bits (949), Expect = e-102, Method: Compositional matrix adjust. Identities = 192/427 (44%), Positives = 262/427 (61%), Gaps = 9/427 (2%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GPS L+D E++ FD ERIPERVVHARG+GA+G F+V S T A L++ ++T Sbjct: 30 GPSFLDDYHLIEKLAHFDRERIPERVVHARGAGAYGVFEVENSMEKHTRAAFLSEEGKQT 89 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 VFVRFSTV+ +GS +T+RD RGFAVKFYTEEGN+DLVGNN+P+FFI+DA+KFPD++H+ Sbjct: 90 DVFVRFSTVIHPKGSPETLRDPRGFAVKFYTEEGNYDLVGNNLPIFFIRDALKFPDMVHS 149 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLI 244 KP+P + + +WDF E+THM TW SD IP + M+G GV+T+ + Sbjct: 150 LKPDPVTNIQDP----DRYWDFMTLTPESTHMLTWLFSDEGIPANYAEMRGSGVHTFRWV 205 Query: 245 NAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQA 304 N G+ +VK+HW P G+ +L +EA ++ D +DL++ IE G YP W +Q Sbjct: 206 NKYGETKYVKYHWRPSEGIRNLSMEEAAEIQANDFQHATRDLYDRIEKGNYPAWDLYVQL 265 Query: 305 IAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGI 364 + D + D+D D TK W E+ P++ +G M LNRNP+ FF +TEQ AF S +V GI Sbjct: 266 MPLSDYDELDYDPCDPTKTWSEEDYPLQKVGRMTLNRNPENFFAETEQAAFTPSALVPGI 325 Query: 365 GFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYY 424 S+D LLQGR FSY DTQ RLG N+ +P+N P PV N +DG M T G +NY Sbjct: 326 EASEDKLLQGRLFSYPDTQRHRLGANYMRIPVNCPYAPVHNNQQDGFMTTTRPSGHINYE 385 Query: 425 PNRFDACPPASLKEGGYLEYAQKVA-GIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMI 483 PNR+D P KE + + ++ V G + + + F QA Y S S EKQ +I Sbjct: 386 PNRYDDQP----KENPHYKESEPVLHGDRMVRQKIEKPNDFKQAGEKYRSYSEEEKQALI 441 Query: 484 NAFGFEL 490 +L Sbjct: 442 KNLTADL 448 >2J2M-A nrPDB Length = 491 Score = 360 bits (924), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 203/481 (42%), Positives = 277/481 (57%), Gaps = 14/481 (2%) Query: 35 TDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHAR 94 + +LTT+ GV D + + GP+LLED E+I FD ER+PERVVHAR Sbjct: 2 NENEKKLTTNQGVP---IGDNQNSRTAGRRGPTLLEDYQLIEKIAHFDRERVPERVVHAR 58 Query: 95 GSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFY 154 G GA G FKV S T A L + E PVF RFSTV+ S +T+RD RGF+VKFY Sbjct: 59 GFGAHGVFKVKNSMKKYTKAAFLQEEGTEVPVFARFSTVIHGTHSPETLRDPRGFSVKFY 118 Query: 155 TEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEAT 214 TEEGNWD VGNN+PVFFI+DA+KFPD++H+ KP+P + + +WDF E+T Sbjct: 119 TEEGNWDFVGNNLPVFFIRDAMKFPDMVHSLKPDPRTNIQDP----DRYWDFMTLRPEST 174 Query: 215 HMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKL 274 +M +D IP S R M+G V+++ +NA G ++K W P+ GVH+L DEA ++ Sbjct: 175 NMLMHIFTDEGIPASYRKMRGSSVHSFKWVNAHGNTVYIKLRWVPKEGVHNLSADEATEV 234 Query: 275 AGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYI 334 G+D + D ++AIENG +P+W +Q + D FDFD LDATK W ED++P +++ Sbjct: 235 QGKDFNHASNDTFQAIENGDFPEWDLFVQVLDPADVENFDFDPLDATKDWFEDVIPFQHV 294 Query: 335 GEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQEL 394 G M LN+N D +F +TE + F +V G+ S+D LLQGR FSY DTQ R+G N+Q+L Sbjct: 295 GTMTLNKNVDNYFAETESVGFNPGVLVPGMLPSEDKLLQGRLFSYSDTQRHRIGPNYQQL 354 Query: 395 PINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKV-AGIKA 453 PIN P V N+ RDGAM +VNY PNR+ P + + Y E Q + I Sbjct: 355 PINCPFAQVNNYQRDGAMPFKQQTSSVNYEPNRYQDEPKQTPE---YTEDTQPLHDDIHG 411 Query: 454 RARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHC--EDPVVYGRMVQRLADIDL 511 R K +F QA Y M+ E+ ++N +L E+ V+ AD L Sbjct: 412 RLEIEK-TNNFGQAGEVYRRMTEEEQMALLNNLVNDLQQVRHENTVLLAICNFYRADASL 470 Query: 512 G 512 G Sbjct: 471 G 471 >1SI8-A nrPDB Length = 484 Score = 359 bits (922), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 193/494 (39%), Positives = 278/494 (56%), Gaps = 22/494 (4%) Query: 37 KSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGS 96 K+ LTT G + D ++ + GP L++D E++ F+ ER+PERVVHA+G+ Sbjct: 2 KNQHLTTSQG---SPVGDNQNSLTAGEFGPVLIQDVHLLEKLAHFNRERVPERVVHAKGA 58 Query: 97 GAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTE 156 GA G FKV +S + T A L++ +ETP+F RFSTV G GS+DT+RD RGFA+KFYT+ Sbjct: 59 GAHGIFKVSQSMAQYTKADFLSEVGKETPLFARFSTVAGELGSSDTLRDPRGFALKFYTD 118 Query: 157 EGNWDLVGNNIPVFFIQDAIKFPDVIHAGK--PEPHNEVPQAQSAHNNFWDFQFNHTEAT 214 EGN+DLVGNN P+FFI+DAIKFPD IH+ K P H + P+A WDF + E+ Sbjct: 119 EGNYDLVGNNTPIFFIRDAIKFPDFIHSQKRNPRTHLKSPEA------VWDFWSHSPESL 172 Query: 215 HMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKL 274 H T MSDR IP S R M GFG +T+ +NA G+ FVK+H+ G+ +L A ++ Sbjct: 173 HQVTILMSDRGIPLSFRHMHGFGSHTFKWVNAAGEVFFVKYHFKTNQGIKNLESQLAEEI 232 Query: 275 AGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYI 334 AG++PDFH +DL AIEN +P W +Q I D + D TK + P+ + Sbjct: 233 AGKNPDFHIEDLHNAIENQEFPSWTLSVQIIPYADALTMKETLFDVTKTVSQKEYPLIEV 292 Query: 335 GEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQEL 394 G M LNRNP+ +F + EQ+ F + V GI S D LLQGR F+Y D R+G N +L Sbjct: 293 GTMTLNRNPENYFAEVEQVTFSPGNFVPGIEASPDKLLQGRLFAYGDAHRHRVGANSHQL 352 Query: 395 PINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKAR 454 PIN+ PV N+ +DG MR +NY PN + P KE + K++ + Sbjct: 353 PINQAKAPVNNYQKDGNMRFNNGNSEINYEPNSYTETP----KE----DPTAKISSFEVE 404 Query: 455 ARSAKF---KEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDL 511 + ++HF+QA YN + EK+++IN L ++ + R + ++ Sbjct: 405 GNVGNYSYNQDHFTQANALYNLLPSEEKENLINNIAASLGQVKNQEIIARQIDLFTRVNP 464 Query: 512 GLAQTIAEMVGGEA 525 +A+ + +A Sbjct: 465 EYGARVAQAIKQQA 478 >2ISA-A nrPDB Length = 483 Score = 350 bits (898), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 175/365 (47%), Positives = 240/365 (65%), Gaps = 5/365 (1%) Query: 63 KIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSR 122 K GP LL+D + E++ FD E IPER +HA+GSGA+G F V + T A + +D + Sbjct: 24 KRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITKYTKAKIFSDIGK 83 Query: 123 ETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVI 182 +T +F RFSTV G RG+AD RD+RGF++KFYTEEGNWDL GNN PVFF++D +KFPD+ Sbjct: 84 KTDMFARFSTVAGERGAADAERDIRGFSLKFYTEEGNWDLAGNNTPVFFLRDPLKFPDLN 143 Query: 183 HAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYT 242 HA K +P + +SA NN WDF + EA H T MSDR IP + R M GFG +T++ Sbjct: 144 HAVKRDPRTNM---RSAKNN-WDFWTSLPEALHQVTIVMSDRGIPATYRHMHGFGSHTFS 199 Query: 243 LINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGI 302 IN+ +R++VKFH+ + G+ +L EA +L G D + H++DL ++I+N +PKW + Sbjct: 200 FINSDNERYWVKFHFVSQQGIKNLSDAEAGELVGNDRESHQRDLLDSIDNQDFPKWTLKV 259 Query: 303 QAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVN 362 Q + E D ++ D TK+WP P+ +GE ELNRNP +F + EQ AF ++VV Sbjct: 260 QIMPEADAATVPYNPFDLTKVWPHKDYPLIEVGEFELNRNPQNYFAEVEQAAFNPANVVP 319 Query: 363 GIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRG-TV 421 GI FS D +LQGR F+Y D Q RLGVN Q +P+N P CPV +++RDGAMR + G T+ Sbjct: 320 GISFSPDKMLQGRLFAYGDAQRYRLGVNHQHIPVNAPRCPVHSYHRDGAMRVDGNFGSTL 379 Query: 422 NYYPN 426 Y PN Sbjct: 380 GYEPN 384 >1M7S-A nrPDB Length = 484 Score = 349 bits (896), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 202/469 (43%), Positives = 274/469 (58%), Gaps = 29/469 (6%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GP LL+D +++ RFD ERIPERVVHARG+G G+F SDL+ A V + +T Sbjct: 25 GPVLLQDVQLLQKLQRFDRERIPERVVHARGTGVKGEFTASADISDLSKATVFK-SGEKT 83 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 PVFVRFS+V+ S +T+RD GFA KFYT +GNWDLVGNN P FFI+DAIKFPD++HA Sbjct: 84 PVFVRFSSVVHGNHSPETLRDPHGFATKFYTADGNWDLVGNNFPTFFIRDAIKFPDMVHA 143 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFNHT-EATHMFTWAMSDRAIPRSLRMMQGFGVNTYTL 243 KP+P + + +DF F+H EAT T S+ P R M G GV+ Y L Sbjct: 144 FKPDPRTNL----DNDSRRFDF-FSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKL 198 Query: 244 INAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQ 303 +NA+G+ H+VKFHW G+ +L E ++ +D DL AI+ G +PKW +Q Sbjct: 199 VNAKGEVHYVKFHWKSLQGIKNLDPKEVAQVQSKDYSHLTNDLVGAIKKGDFPKWDLYVQ 258 Query: 304 AIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNG 363 + E+ KFDFD LDATKIWP+ VP + IG+M LN+N D FF +TEQ+A +++V G Sbjct: 259 VLKPEELAKFDFDPLDATKIWPD--VPEKKIGQMVLNKNVDNFFQETEQVAMAPANLVPG 316 Query: 364 IGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNY 423 I S+D LLQGR FSY DTQ+ RLG N LP+N+P V N N+DGA+ + VNY Sbjct: 317 IEPSEDRLLQGRVFSYADTQMYRLGANGLSLPVNQPKVAVNNGNQDGALNTGHTTSGVNY 376 Query: 424 YPNRFDACPPASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMI 483 P+R + P + Y E ++G +A+ + +++F QA Y S S EK ++ Sbjct: 377 EPSRLEPRPADD--KARYSELP--LSGTTQQAKITR-EQNFKQAGDLYRSYSAKEKTDLV 431 Query: 484 NAFGFELD--------------HCEDPVVYGRMVQRLADIDLGLAQTIA 518 FG L + EDP YG V +A DL +++A Sbjct: 432 QKFGESLADTLTESKNIMLSYLYKEDP-NYGTRVAEVAKGDLSKVKSLA 479 >3HB6-A nrPDB Length = 484 Score = 344 bits (883), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 182/433 (42%), Positives = 253/433 (58%), Gaps = 15/433 (3%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GP LL+D + E++ FD E IPER + A+GSGAFG F V + T A + ++ ++T Sbjct: 27 GPMLLQDVWFLEKLAHFDREVIPERRMFAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKT 86 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 +F RFSTV G RG+AD RD+RGFA+KFYTEEGNWD+VGNN PVF+++D +KFPD+ H Sbjct: 87 EMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFYLRDPLKFPDLNHI 146 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLI 244 K +P + WDF + E+ H T MSDR +P S R + GFG +TY+ I Sbjct: 147 VKRDPRTNMRNMAYK----WDFFSHLPESLHQLTIDMSDRGLPLSYRFVHGFGSHTYSFI 202 Query: 245 NAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQA 304 N +R +VKFH+ + G+ +L+ DEA L G+D + ++DL+EAIE G YP+WK IQ Sbjct: 203 NKDNERFWVKFHFRCQQGIKNLMDDEAEALVGKDRESSQRDLFEAIERGDYPRWKLQIQI 262 Query: 305 IAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGI 364 + E++ ++ D TK+WP P+ +G ELNRNPD +F EQ AF +++V GI Sbjct: 263 MPEKEASTVPYNPFDLTKVWPHADYPLMDVGYFELNRNPDNYFSDVEQAAFSPANIVPGI 322 Query: 365 GFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGT-VNY 423 FS D +LQGR FSY D RLGVN ++P+N P CP N++RDGAMR + G + Y Sbjct: 323 SFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAPKCPFHNYHRDGAMRVDGNSGNGITY 382 Query: 424 YPNR---FDACPPASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQ 480 PN F P + E + G + +++FSQ + Y +S E Q Sbjct: 383 EPNSGGVFQEQP-------DFKEPPLSIEGAADHWNHREDEDYFSQPRALYELLSDDEHQ 435 Query: 481 HMINAFGFELDHC 493 M EL Sbjct: 436 RMFARIAGELSQA 448 >4CAB-A nrPDB Length = 536 Score = 338 bits (866), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 197/468 (42%), Positives = 266/468 (56%), Gaps = 21/468 (4%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVY-----ESASDLTMAPVLTD 119 GP LE+ E++ FD ERIPERVVHARG GA G F+ E S T A + + Sbjct: 54 GPMTLENYQFIEKLSHFDRERIPERVVHARGVGAHGVFRATGKVGDEPVSKYTRAKLFQE 113 Query: 120 TSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFP 179 +ETPVFVRFSTV S +T+RD RGFAVKFYTE+GNWDLVGNN+ +FFI+DA+KFP Sbjct: 114 DGKETPVFVRFSTVGHGTHSPETLRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDALKFP 173 Query: 180 DVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVN 239 D+IH+ KP P + + +DF EATHM T S IP S R MQG GVN Sbjct: 174 DLIHSQKPSPTTNI----QSQERIFDFFAGSPEATHMITLLYSPWGIPASYRFMQGSGVN 229 Query: 240 TYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWK 299 TY +N QG+ VK+HW P GV +L +A ++ + + +DL +AIE G +P+W Sbjct: 230 TYKWVNDQGEGVLVKYHWEPVQGVRNLTQMQADEVQATNFNHATQDLHDAIERGDFPQWD 289 Query: 300 FGIQAIAEEDEH-KFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTS 358 +Q I E+ EH + DFD LD TKIWP + P R++G+M LNRNP+ F +TEQ AF T Sbjct: 290 LFVQ-IMEDGEHPELDFDPLDDTKIWPREQFPWRHVGQMTLNRNPENVFAETEQAAFGTG 348 Query: 359 HVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISR 418 +V+G+ FSDD +LQGR FSY DTQ R+G N+ +LPIN P V RDG M + + Sbjct: 349 VLVDGLDFSDDKMLQGRTFSYSDTQRYRVGPNYLQLPINAPKKHVATNQRDGQMAYRVDT 408 Query: 419 -----GTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNS 473 VNY P+ A + E+ +V G RA + + F QA + Y + Sbjct: 409 FEGQDQRVNYEPSLLSGPKEAPRRA---PEHTPRVEGNLVRA-AIERPNPFGQAGMQYRN 464 Query: 474 MSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMV 521 + E+ +++ L D + +M++ D Q + E + Sbjct: 465 FADWERDELVSNLSGALAGV-DKRIQDKMLEYFTAADADYGQRVREGI 511 >1QQW-A nrPDB Length = 527 Score = 331 bits (848), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 187/457 (40%), Positives = 263/457 (57%), Gaps = 21/457 (4%) Query: 20 PSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIM 79 P+S ++ K E + K+ LTT G D L +++ GP L++D + + Sbjct: 7 PASDQMQHWK-EQRAAQKADVLTTGAG---NPVGDKLNVITVGPRGPLLVQDVVFTDEMA 62 Query: 80 RFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGS 139 FD ERIPERVVHA+G+GAFG F+V + + A V ++TP+ VRFSTV G GS Sbjct: 63 HFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGS 122 Query: 140 ADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSA 199 ADTVRD RGFAVKFYTE+GNWDLVGNN P+FFI+D I FP IH+ K P + Sbjct: 123 ADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMV 182 Query: 200 HNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTP 259 WDF E+ H ++ SDR IP R M G+G +T+ L+NA G+ + KFH+ Sbjct: 183 ----WDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKT 238 Query: 260 ELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILD 319 + G+ +L ++A +L+ +DPD+ +DL+ AI G YP W F IQ + F F+ D Sbjct: 239 DQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFD 298 Query: 320 ATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSY 379 TK+WP P+ +G++ LNRNP +F + EQIAF S++ GI S D +LQGR F+Y Sbjct: 299 LTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAY 358 Query: 380 FDTQISRLGVNFQELPINRPVCP----VMNFNRDGAMRHTISRGTV-NYYPNRFDACPPA 434 DT RLG N+ +P+N CP V N+ RDG M ++G NYYPN F A Sbjct: 359 PDTHRHRLGPNYLHIPVN---CPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFG----A 411 Query: 435 SLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFY 471 ++ LE++ + +G R +A ++ +Q + FY Sbjct: 412 PEQQPSALEHSIQYSGEVRRFNTAN-DDNVTQVRAFY 447 >4E37-A nrPDB Length = 484 Score = 328 bits (841), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 175/468 (37%), Positives = 268/468 (57%), Gaps = 27/468 (5%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GP LL+D + E++ FD E IPER +HA+GS A+G F V + T A + + ++T Sbjct: 26 GPMLLQDVWFLEKLAHFDREVIPERRMHAKGSAAYGTFTVTHDITPYTRAKIFSQVGKKT 85 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 +F+RFSTV G RG+AD RD+RGF+++FYTE+GNWDLVGNN PVF+++D +KFPD+ H Sbjct: 86 DMFLRFSTVAGERGAADAERDIRGFSMRFYTEQGNWDLVGNNTPVFYLRDPLKFPDLNHV 145 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLI 244 K +P + A WDF + E+ H T SDR +P+S R + GFG +T++ I Sbjct: 146 VKRDPRTNLRNATFK----WDFFSHLPESLHQLTIDFSDRGLPKSYRHIHGFGSHTFSFI 201 Query: 245 NAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQA 304 NA +R +VKFH+ + G+ +L EA ++ QD + ++DL+E+IE G +P+WK +Q Sbjct: 202 NANNERFWVKFHFKTQQGIENLTNAEAAEVIAQDRESSQRDLYESIEKGDFPRWKMYVQI 261 Query: 305 IAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGI 364 + E++ + ++ D TK+WP P+ +G ELNRNPD +F + EQ AF ++VV GI Sbjct: 262 MPEKEAATYRYNPFDLTKVWPHGDYPLIEVGFFELNRNPDNYFAEVEQAAFTPANVVPGI 321 Query: 365 GFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMR--HTISRGTVN 422 GFS D +LQGR FSY D RLGVN ++P+N CP ++RDG MR + V Sbjct: 322 GFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAARCPHQVYHRDGGMRVDGNNAHQRVT 381 Query: 423 YYPNRFD--------ACPPASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSM 474 Y PN F+ + PP SL EG + +V +++SQ ++ Sbjct: 382 YEPNSFNQWQEQPDFSEPPLSL-EGAADHWNHRVD-----------DDYYSQPAALFHLF 429 Query: 475 SPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMVG 522 + +KQ + ++ + + R + +D + +A+ +G Sbjct: 430 TDEQKQRLFANIAEDIRDVPEQ-IQRRQIGLFLKVDPAYGKGVADALG 476 >2XQ1-A nrPDB Length = 509 Score = 327 bits (837), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 169/374 (45%), Positives = 227/374 (60%), Gaps = 13/374 (3%) Query: 64 IGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRE 123 IGP LL+D + + FD ERIPERVVHA+G+GA+G F+V + +D+ A L ++ Sbjct: 39 IGPLLLQDFKLIDTLSHFDRERIPERVVHAKGAGAYGVFEVTDDITDVCSAKFLDTVGKK 98 Query: 124 TPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIH 183 T +F RFSTV G +GSADT RD RGFA KFYTE+GN DLV NN P+FFI+D IKFP IH Sbjct: 99 TRIFTRFSTVGGEKGSADTARDPRGFATKFYTEDGNLDLVYNNTPIFFIRDPIKFPHFIH 158 Query: 184 AGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTL 243 K P + N FWD+ + E+ H + S+R P S R M G+ +TY Sbjct: 159 TQKRNPATNLKDP----NMFWDYLTANDESLHQVMYLFSNRGTPASYRTMNGYSGHTYKW 214 Query: 244 INAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQ 303 N++G+ +V+ H+ GVH+L+ +EA +LAG+DPD +DLWEAIE G YP W+ IQ Sbjct: 215 YNSKGEWVYVQVHFIANQGVHNLLDEEAGRLAGEDPDHSTRDLWEAIEKGDYPSWECYIQ 274 Query: 304 AIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNG 363 + E K F + D TK+WP P+R+ G LN NP ++ +TEQIAF SH V G Sbjct: 275 TMTLEQSKKLPFSVFDLTKVWPHKDFPLRHFGRFTLNENPKNYYAETEQIAFSPSHTVPG 334 Query: 364 IGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMN-----FNRDGAMRHTISR 418 + S+DP+LQ R FSY DT RLG N+ ++P+N CP+ + NRDG M + Sbjct: 335 MEPSNDPVLQSRLFSYPDTHRHRLGPNYHQIPVN---CPLKSGSFNPINRDGPMCVDGNL 391 Query: 419 GTVNYYPNRFDACP 432 G Y N ++ CP Sbjct: 392 GGTPNYANAYN-CP 404 >5GKN-A nrPDB Length = 527 Score = 325 bits (832), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 187/457 (40%), Positives = 259/457 (56%), Gaps = 21/457 (4%) Query: 20 PSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIM 79 P+S ++ K E + K LTT G D L ++ GP L++D + + Sbjct: 7 PASDQMKHWK-EQRAAQKPDVLTTGGG---NPVGDKLNSLTVGPRGPLLVQDVVFTDEMA 62 Query: 80 RFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGS 139 FD ERIPERVVHA+G+GAFG F+V + + A V + TP+ VRFSTV G GS Sbjct: 63 HFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGS 122 Query: 140 ADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSA 199 ADTVRD RGFAVKFYTE+GNWDLVGNN P+FFI+DA+ FP IH+ K P + Sbjct: 123 ADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMV 182 Query: 200 HNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTP 259 WDF E+ H ++ SDR IP R M G+G +T+ L+NA G+ + KFH+ Sbjct: 183 ----WDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKT 238 Query: 260 ELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILD 319 + G+ +L ++A +LA +DPD+ +DL+ AI G YP W IQ + + F F+ D Sbjct: 239 DQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFD 298 Query: 320 ATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSY 379 TK+WP P+ +G++ LNRNP +F + EQ+AF S++ GI S D +LQGR F+Y Sbjct: 299 LTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAY 358 Query: 380 FDTQISRLGVNFQELPINRPVCP----VMNFNRDGAMRHTISRGTV-NYYPNRFDACPPA 434 DT RLG N+ ++P+N CP V N+ RDG M ++G NYYPN F A Sbjct: 359 PDTHRHRLGPNYLQIPVN---CPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFS----A 411 Query: 435 SLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFY 471 + LE+ +G R SA ++ +Q + FY Sbjct: 412 PEHQPSALEHRTHFSGDVQRFNSAN-DDNVTQVRTFY 447 >4B7G-A nrPDB Length = 515 Score = 311 bits (796), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 160/380 (42%), Positives = 230/380 (60%), Gaps = 13/380 (3%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GP++L D E++ F+ E +PER+ HA+G GAFG+ + E S+ T A + + T Sbjct: 43 GPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGELHITEDVSEYTKADLFQ-PGKVT 101 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 P+ VRFSTV G +GS DT RDV GFA++FYTEEGN+D+VGNN P FF++D +KFPD IH+ Sbjct: 102 PLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIVGNNTPTFFLRDGMKFPDFIHS 161 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLI 244 K N + A WDF E+ H T+ M DR P++ R GFG +T+ I Sbjct: 162 QKRLNKNGLRDADMQ----WDFWTRAPESAHQVTYLMGDRGTPKTSRHQDGFGSHTFQWI 217 Query: 245 NAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQA 304 NA+GK +VK+H+ G EA K+AG++ D+ R+DL+ AIENG +P W +Q Sbjct: 218 NAEGKPVWVKYHFKTRQGWDCFTDAEAAKVAGENADYQREDLYNAIENGDFPIWDVKVQI 277 Query: 305 IAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGI 364 + ED + ++ D TK W + P+ +G LNRNP FF Q EQIA ++V G+ Sbjct: 278 MPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPRNFFAQIEQIALDPGNIVPGV 337 Query: 365 GFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTI-SRGTVNY 423 G S D +LQ R F+Y D Q R+G N+++LP+NRP+ V ++R+G+M++ + G +Y Sbjct: 338 GLSPDRMLQARIFAYADQQRYRIGANYRDLPVNRPINEVNTYSREGSMQYIFDAEGEPSY 397 Query: 424 YPNRFDACPPASLKEGGYLE 443 PNR+D K GYL+ Sbjct: 398 SPNRYD-------KGAGYLD 410 >1GWF-A nrPDB Length = 503 Score = 310 bits (793), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 166/364 (45%), Positives = 223/364 (61%), Gaps = 9/364 (2%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GP +L D E F+ IPER HA+GSGAFG+F+V E S T A V ++ T Sbjct: 34 GPIVLHDTHLLETHQHFNRMNIPERRPHAKGSGAFGEFEVTEDVSKYTKALVFQPGTK-T 92 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 +RFSTV G GS DT RDVRGFA++FYTEEGN+DLVGNN P+FF++D +KF I + Sbjct: 93 ETLLRFSTVAGELGSPDTWRDVRGFALRFYTEEGNYDLVGNNTPIFFLRDPMKFTHFIRS 152 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLI 244 K P + + A WDF N+ E+ H T+ M R +PR+ R M G+G +TY + Sbjct: 153 QKRLPDSGLRDATMQ----WDFWTNNPESAHQVTYLMGPRGLPRTWREMNGYGSHTYLWV 208 Query: 245 NAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQA 304 NAQG++H+VK+H+ + GVH+L DEA K+AG++ DFHR+DL+E+I G +PKW IQA Sbjct: 209 NAQGEKHWVKYHFISQQGVHNLSNDEATKIAGENADFHRQDLFESIAKGDHPKWDLYIQA 268 Query: 305 IAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGI 364 I E+ + F+ D TK + P +G + LNRNP+ F Q E AF S+ V GI Sbjct: 269 IPYEEGKTYRFNPFDLTKTISQKDYPRIKVGTLTLNRNPENHFAQIESAAFSPSNTVPGI 328 Query: 365 GFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAM--RHTISRGTVN 422 G S D +L GR F+Y D Q+ R+G + +LP+NRP V N+ +G M HT R T Sbjct: 329 GLSPDRMLLGRAFAYHDAQLYRVGAHVNQLPVNRPKNAVHNYAFEGQMWYDHTGDRST-- 386 Query: 423 YYPN 426 Y PN Sbjct: 387 YVPN 390 >1A4E-A nrPDB Length = 488 Score = 288 bits (737), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 177/475 (37%), Positives = 248/475 (52%), Gaps = 36/475 (7%) Query: 65 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 124 GP LL+D + + F+ E IP+R HA GSGAFG F+V + +D+ + + + + T Sbjct: 29 GPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRT 88 Query: 125 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 184 RFSTV G +GSADTVRD RGFA KFYTEEGN D V NN PVFFI+D KFP IH Sbjct: 89 KCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHT 148 Query: 185 GKPEPHNEVPQAQSAHNNFWDFQFN--HTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYT 242 K P + A + FWDF + A H SDR P + R M G+ +TY Sbjct: 149 QKRNPQTNLRDA----DMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYK 204 Query: 243 LINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGI 302 N G H+V+ H + G+ +L +EA K+AG +PD+ ++DL+EAI+NG YP W I Sbjct: 205 WSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYI 264 Query: 303 QAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVN 362 Q + E D K F + D TK+WP+ P+R +G++ LN NP FF Q EQ AF S V Sbjct: 265 QTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVP 324 Query: 363 GIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMN--FN---RDGAMRHTIS 417 S DP+LQ R FSY D RLG NF ++P+N CP + FN RDG M + Sbjct: 325 YQEASADPVLQARLFSYADAHRYRLGPNFHQIPVN---CPYASKFFNPAIRDGPMNVNGN 381 Query: 418 RGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARARSAKFKEH---------FSQAQ 468 G+ Y A+ K Y++ + + + H F QA+ Sbjct: 382 FGSEPTY--------LANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVDFVQAR 433 Query: 469 LFYNSM--SPIEKQHMINAFGFELD-HCEDPVVYGRMVQRLADIDLGLAQTIAEM 520 Y + P +++++ G ++ C P + R+ A +D GL++ I ++ Sbjct: 434 NLYRVLGKQPGQQKNLAYNIGIHVEGAC--PQIQQRVYDMFARVDKGLSEAIKKV 486 >1YE9-A nrPDB Length = 226 Score = 276 bits (706), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 137/222 (61%), Positives = 162/222 (72%), Gaps = 3/222 (1%) Query: 41 LTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFG 100 LTT+ GV+ + LR S GP+LLED RE+I FDHERIPER+VHARGS A G Sbjct: 6 LTTNQGVRIADDQNSLRAGSR---GPTLLEDFILREKITHFDHERIPERIVHARGSAAHG 62 Query: 101 KFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNW 160 F+ Y+S SD+T A L+D ++ TPVFVRFSTV G GSADTVRD+RGFA KFYTEEG + Sbjct: 63 YFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIF 122 Query: 161 DLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWA 220 DLVGNN P+FFIQDA KFPD +HA KPEPH +PQ QSAH+ FWD+ E H WA Sbjct: 123 DLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWA 182 Query: 221 MSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELG 262 MSDR IPRS R M+GFG++T+ LINA+GK FV+FHW P G Sbjct: 183 MSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAG 224 >1YE9-E nrPDB Length = 259 Score = 272 bits (696), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 136/257 (52%), Positives = 174/257 (67%), Gaps = 5/257 (1%) Query: 273 KLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVR 332 KL G+DPDFHR++LWEAIE G +P+++ G Q I EEDE KFDFD+LD TK+ PE+LVPV+ Sbjct: 1 KLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQ 60 Query: 333 YIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL-GVNF 391 +G+M LNRNPD FF + EQ AF H+V G+ F++DPLLQGR FSY DTQISRL G NF Sbjct: 61 RVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNF 120 Query: 392 QELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRF-DACP---PASLKEGGYLEYAQK 447 E+PINRP CP NF RDG R I NY PN D P P K GG+ Y ++ Sbjct: 121 HEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQER 180 Query: 448 VAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLA 507 V G K R RS F E++S +LF+ S +P E++H+++ F FEL P + R+V +LA Sbjct: 181 VEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLA 240 Query: 508 DIDLGLAQTIAEMVGGE 524 IDL LAQ +A+ +G E Sbjct: 241 HIDLTLAQAVAKNLGIE 257 >3E4Y-A nrPDB Length = 320 Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 74/303 (24%), Positives = 118/303 (38%), Gaps = 23/303 (7%) Query: 89 RVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRG 148 R +HA+G+ G F A L+ AP L ++ P +RFS G+ D VRG Sbjct: 32 RALHAKGTLYRGTFTATRDAVMLSAAPHLDGST--VPALIRFSNGSGNPKQRDGAPGVRG 89 Query: 149 FAVKFYTEEGNWDLVGNNIPVFFIQDAIK-FPDVIHAGKPEPHNEVPQAQSAHNNFWDFQ 207 AVKF +G+ V + + F D++ A + P P + H Sbjct: 90 MAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMR--PGLTTPLRLATH------L 141 Query: 208 FNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLV 267 H IP S + G++ + I A G FV++H P L Sbjct: 142 LTHPRLLGALPLLREANRIPASYATTEYHGLHAFRWIAADGSARFVRYHLVPTAAEEYLS 201 Query: 268 WDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPED 327 +A G+DPDF +L +++G ++ F +Q D +D + W Sbjct: 202 ASDA---RGKDPDFLTDELAARLQDGPV-RFDFRVQIAGPTDS------TVDPSSAWQS- 250 Query: 328 LVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL 387 + +G + + E + + F V +GI SDDP+L+ R Y + R Sbjct: 251 -TQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRT 309 Query: 388 GVN 390 GV+ Sbjct: 310 GVD 312 >2VRN-A nrPDB Length = 190 Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust. Identities = 23/108 (21%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 553 IKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPH------ 606 + +++AI+ ADG + + + AAI A +I ++ + G ++P Sbjct: 7 LTGKKIAILAADGVEEIELTSPRAAIEAAGGTTELISLEPGEIQSMKGD-IEPQEKYRVD 65 Query: 607 HHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGA 654 H + + + D + +PGG + L A+ ++R+ + K I A Sbjct: 66 HVVSEVQVSDYDGLLLPGGTVNPDKLRLEEGAMKFVRDMYDAGKPIAA 113 >3L18-A nrPDB Length = 168 Score = 32.7 bits (73), Expect = 0.60, Method: Compositional matrix adjust. Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 1/114 (0%) Query: 555 SRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRS 614 S +V + ADG++++ I V +R K+T +G +V E Sbjct: 2 SMKVLFLSADGFEDLELIYPLHRIKEEGHEVYVASFQRGKITGKHGYSVNVDLTFEEVDP 61 Query: 615 TMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIAL 668 DA+ +PGG KA E + N +A+ R F K + + ++ A L Sbjct: 62 DEFDALVLPGG-KAPEIVRLNEKAVMITRRMFEDDKPVASICHGPQILISAKVL 114 >4TYM-A nrPDB Length = 258 Score = 32.0 bits (71), Expect = 0.95, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 608 HLEGFRSTMVDAIFIPGGAKAAETLSKN----GRALHWIREAFGHLKAIGATGEAVDLVA 663 H+E + + D I +PG A+ +++N + +R FG+ G V ++ Sbjct: 26 HIEAKQGEIADKILLPGDPLRAKFIAENFLEDAVCFNTVRNMFGYTGTY--KGHRVSVMG 83 Query: 664 KAIALPQVTVSSEAEVHESYGVVTLKKV 691 + +P +++ + E+ YGV TL +V Sbjct: 84 TGMGMPSISIYAR-ELIVDYGVKTLIRV 110 >1YXA-A nrPDB Length = 398 Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 38/62 (61%), Gaps = 4/62 (6%) Query: 649 LKAIGATGEAVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAG 708 L ++GA G ++ + + + +T +SEA++H+ +G + + +P+ D V+I+ G+A Sbjct: 64 LVSLGAKGNTLEEILEGLKF-NLTETSEADIHQGFGHLLQRLNQPK---DQVQISTGSAL 119 Query: 709 FL 710 F+ Sbjct: 120 FI 121 >3KBG-A nrPDB Length = 213 Score = 28.9 bits (63), Expect = 9.1, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 593 SKVTAANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLS 633 SK+ A GS+ H EGF ST+ D +F+ G +K + LS Sbjct: 160 SKIEAKEGSSANLVHFQEGF-STIKDHVFMIGSSKFSFVLS 199 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1SY7-A nrPDB 1069 0.0 3TTT-A nrPDB 923 0.0 4B7A-A nrPDB 861 0.0 2IUF-A nrPDB 837 0.0 4BIM-A nrPDB 815 0.0 2IQF-A nrPDB 711 0.0 1SI8-A nrPDB 698 0.0 5GKN-A nrPDB 696 0.0 3HB6-A nrPDB 693 0.0 1QQW-A nrPDB 693 0.0 4E37-A nrPDB 691 0.0 4QOP-A nrPDB 683 0.0 2ISA-A nrPDB 678 0.0 2J2M-A nrPDB 668 0.0 4CAB-A nrPDB 636 0.0 2XQ1-A nrPDB 631 0.0 1A4E-A nrPDB 607 e-174 1M7S-A nrPDB 605 e-173 4B7G-A nrPDB 592 e-169 1GWF-A nrPDB 582 e-166 1YE9-A nrPDB 364 e-101 1YE9-E nrPDB 361 e-100 3E4Y-A nrPDB 306 2e-83 Sequences not found previously or not previously below threshold: 1U5U-A nrPDB 60 4e-09 2VRN-A nrPDB 44 3e-04 1G2I-A nrPDB 42 0.001 3L18-A nrPDB 41 0.003 2W8Z-A nrPDB 35 0.097 4K2H-A nrPDB 34 0.18 4O8M-A nrPDB 34 0.27 3NVQ-A nrPDB 34 0.28 5U5I-A nrPDB 32 0.64 1Y11-A nrPDB 32 0.67 4OUA-B nrPDB 32 0.71 1QMG-A nrPDB 32 1.2 6BHF-A nrPDB 32 1.3 5EZ1-A nrPDB 32 1.3 2J63-A nrPDB 32 1.3 1U10-A nrPDB 31 1.5 2DIE-A nrPDB 31 2.7 3FAW-A nrPDB 30 4.0 >1SY7-A nrPDB Length = 715 Score = 1069 bits (2763), Expect = 0.0, Method: Composition-based stats. Identities = 715/715 (100%), Positives = 715/715 (100%) Query: 22 SKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRF 81 SKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRF Sbjct: 1 SKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRF 60 Query: 82 DHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSAD 141 DHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSAD Sbjct: 61 DHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSAD 120 Query: 142 TVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHN 201 TVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHN Sbjct: 121 TVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHN 180 Query: 202 NFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPEL 261 NFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPEL Sbjct: 181 NFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPEL 240 Query: 262 GVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDAT 321 GVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDAT Sbjct: 241 GVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDAT 300 Query: 322 KIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFD 381 KIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFD Sbjct: 301 KIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFD 360 Query: 382 TQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGY 441 TQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGY Sbjct: 361 TQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGY 420 Query: 442 LEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGR 501 LEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGR Sbjct: 421 LEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGR 480 Query: 502 MVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII 561 MVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII Sbjct: 481 MVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII 540 Query: 562 IADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIF 621 IADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIF Sbjct: 541 IADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIF 600 Query: 622 IPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHE 681 IPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHE Sbjct: 601 IPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHE 660 Query: 682 SYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY 736 SYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY Sbjct: 661 SYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY 715 >3TTT-A nrPDB Length = 753 Score = 923 bits (2386), Expect = 0.0, Method: Composition-based stats. Identities = 338/730 (46%), Positives = 436/730 (59%), Gaps = 51/730 (6%) Query: 15 ALTSAPSSKKVDDLKNEFKETDKSAR-------LTTDYGVKQTTADDWLRIVSDDKIGPS 67 A +AP S K D +NE + + R LTT+ GV+ + LR GP+ Sbjct: 47 AQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLR---AGSRGPT 103 Query: 68 LLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVF 127 LLED RE+I FDHERIPER+VHARGS A G F+ Y+S SD+T A L+D ++ TPVF Sbjct: 104 LLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVF 163 Query: 128 VRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKP 187 VRFSTV G GSADTVRD+RGFA KFYTEEG +DLVGNN P+FFIQDA KFPD +HA KP Sbjct: 164 VRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKP 223 Query: 188 EPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQ 247 EPH +PQ QSAH+ FWD+ E H WAMSDR IPRS R M+GFG++T+ LINA+ Sbjct: 224 EPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAE 283 Query: 248 GKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAE 307 GK FV+FHW P G SLVWDEA KL G+DPDFHR++LWEAIE G +P+++ G Q I E Sbjct: 284 GKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPE 343 Query: 308 EDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFS 367 EDE KFDFD+LD TK+ PE+LVPV+ +G+M LNRNPD FF + EQ AF H+V G+ F+ Sbjct: 344 EDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFT 403 Query: 368 DDPLLQGRNFSYFDTQISRL-GVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPN 426 +DPLLQGR +SY DTQISRL G NF E+PINRP CP NF RDG R I NY PN Sbjct: 404 NDPLLQGRLYSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPN 463 Query: 427 RFDA----CPPASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHM 482 + P K GG+ Y ++V G K R RS F E++S +LF+ S +P E++H+ Sbjct: 464 SINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHI 523 Query: 483 INAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMVGGEAP------TTTNHPNHGR 536 ++ F FEL P + R+V +LA IDL LAQ +A+ +G E T N + Sbjct: 524 VDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIELTDDQLNITPPPDVNGLK 583 Query: 537 KTINLSQTEFPPATPTIKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVT 596 K +LS P +K R VAI++ D + A A+ A ++ R +VT Sbjct: 584 KDPSLSLYAIPDG--DVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVT 641 Query: 597 AANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATG 656 A +G+ + G S VDA+ +P G A ++ NG A +++ EA+ HLK I G Sbjct: 642 ADDGTVLPIAATFAGAPSLTVDAVIVPCGNIA--DIADNGDANYYLMEAYKHLKPIALAG 699 Query: 657 EAVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAG-FLGEFFY 715 +A A + ++ + E G+V A A G F+ E Sbjct: 700 DARKFKAT------IKIADQGE----EGIVE---------------ADSADGSFMDELLT 734 Query: 716 AIAQHRNWDR 725 +A HR W R Sbjct: 735 LMAAHRVWSR 744 >4B7A-A nrPDB Length = 719 Score = 861 bits (2223), Expect = 0.0, Method: Composition-based stats. Identities = 270/693 (38%), Positives = 380/693 (54%), Gaps = 35/693 (5%) Query: 32 FKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVV 91 ++ D + LT+D G + GP+LLED R++I FDHER+PER V Sbjct: 47 YEVDDSTGYLTSDVGGPIQD----QTSLKAGIRGPTLLEDFMFRQKIQHFDHERVPERAV 102 Query: 92 HARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAV 151 HARG+GA G F Y S++T A L T ++TPVFVRFSTV GSRGSADT RDV GFA Sbjct: 103 HARGAGAHGTFTSYADWSNITAASFLNATGKQTPVFVRFSTVAGSRGSADTARDVHGFAT 162 Query: 152 KFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHT 211 +FYT+EGN+D+VGNNIPVFFIQDAI+FPD+IH+ KP P NE+PQA +AH++ WDF Sbjct: 163 RFYTDEGNFDIVGNNIPVFFIQDAIQFPDLIHSVKPRPDNEIPQAATAHDSAWDFFSQQP 222 Query: 212 EATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEA 271 H WAMS IPRS R M GFGV+T+ + G +K+H+ G SLVW+EA Sbjct: 223 STMHTLFWAMSGHGIPRSYRHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEA 282 Query: 272 LKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPV 331 L+G++ DFHR+DLW+AIE+G P+W +Q + E F FD+LD TKI PE+ P+ Sbjct: 283 QVLSGKNADFHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAPL 342 Query: 332 RYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL-GVN 390 +G ++L+RNP +F +TEQ+ F H+V GI F++DPLLQGR FSY DTQ++R G N Sbjct: 343 TKLGLLKLDRNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYLDTQLNRNGGPN 402 Query: 391 FQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKE----GGYLEYAQ 446 F++LPIN P P+ N NRDGA + I R Y PN ++ P + G + + Sbjct: 403 FEQLPINMPRVPIHNNNRDGAGQMFIHRNKYPYTPNTLNSGYPRQANQNAGRGFFTAPGR 462 Query: 447 KVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRL 506 +G R S F +H+SQ +LF+NS++P+E+Q ++NA FE+ + V ++ +L Sbjct: 463 TASGALVREVSPTFNDHWSQPRLFFNSLTPVEQQFLVNAMRFEISLVKSEEVKKNVLTQL 522 Query: 507 ADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAIIIADGY 566 + +A +A +G AP + H KT +S P PTIK+ RV I+ A Sbjct: 523 NRVSHDVAVRVAAAIGLGAPDADDTYYHNNKTAGVSIVGSGP-LPTIKTLRVGIL-ATTS 580 Query: 567 DNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIFIPGGA 626 ++ A D A + + LV+ + T +T D + + GA Sbjct: 581 ESSALDQAAQLRTRLEKDGLVVTVVAETLREGVDQTYSTAD------ATGFDGVVVVDGA 634 Query: 627 ------KAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVH 680 A+ L GR L +A+ K +G G V A +P+ Sbjct: 635 AALFASTASSPLFPTGRPLQIFVDAYRWGKPVGVCGGKSSEVLDAADVPE---------- 684 Query: 681 ESYGVVTLKKVKPESFTDAVKIAKGAAGFLGEF 713 + GV + + V + F + + F F Sbjct: 685 DGDGVYSEESV--DMFVEEFEKGLATFRFTDRF 715 >2IUF-A nrPDB Length = 688 Score = 837 bits (2161), Expect = 0.0, Method: Composition-based stats. Identities = 278/716 (38%), Positives = 386/716 (53%), Gaps = 68/716 (9%) Query: 30 NEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPER 89 ++F D+ LT++ G +S + G +LL+D RE+I RFDHER+PER Sbjct: 5 SQFYLNDQDVYLTSNVGGPIQDE----NSLSAGQRGATLLQDFIFREKIQRFDHERVPER 60 Query: 90 VVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGF 149 VHARG+GA G F Y S+LT A L+ +ETP+F RFSTV GSRGSADT RDV GF Sbjct: 61 AVHARGTGAHGTFTSYGDWSNLTAASFLSAEGKETPMFTRFSTVAGSRGSADTARDVHGF 120 Query: 150 AVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFN 209 A +FYT+EGN+D+VGNNIPVFFIQDAI FPD+IHA KP N++PQA +AH++ WDF Sbjct: 121 ATRFYTDEGNFDIVGNNIPVFFIQDAILFPDLIHAVKPRGDNQIPQAATAHDSAWDFFSQ 180 Query: 210 HTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWD 269 H WAM+ IPRS R + GFGV+T+ L+ GK VKFHW G S VW+ Sbjct: 181 QPSVLHTLLWAMAGHGIPRSFRHVNGFGVHTFRLVTDDGKTKLVKFHWKGLQGKASFVWE 240 Query: 270 EALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLV 329 EA + AG++ DF R+DL+++I+ G +P+W+ G+Q + E+D+ KF FD+LD TKI PE+LV Sbjct: 241 EAQQTAGKNADFMRQDLFQSIQAGRFPEWELGVQIMQEQDQLKFGFDLLDPTKIVPEELV 300 Query: 330 PVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL-G 388 PV +G+M+LNRNP +F +TEQ+ F H+V G+ F++DPLLQGR FSY DTQ++R G Sbjct: 301 PVTILGKMQLNRNPMNYFAETEQVMFQPGHIVRGVDFTEDPLLQGRLFSYLDTQLNRHGG 360 Query: 389 VNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKE----GGYLEY 444 NF++LPINRP P+ N NRDGA + I Y PN + P E G + Sbjct: 361 PNFEQLPINRPRAPIHNNNRDGAGQMFIPLDPNAYSPNTENKGSPKQANETVGKGFFTAP 420 Query: 445 AQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQ 504 + +G R S F+ ++SQ +LF+NS+ +K+ +++A FE + VV ++ Sbjct: 421 ERTASGKLQRTLSTTFENNWSQPRLFWNSLVNAQKEFIVDAMRFETSNVSSSVVRDDVII 480 Query: 505 RLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAII--- 561 +L I LA +A +G EAP + H T ++ F + +V ++ Sbjct: 481 QLNRISDNLATRVASAIGVEAPKPNSSFYHDNTTAHIG--AFGEKLAKLDGLKVGLLASV 538 Query: 562 -----IADGYD-------------------NVAYDAAYAAISANQAIPLVIGPRRSKVTA 597 IA G D Y+A A Q +V+ + Sbjct: 539 NKPASIAQGAKLQVALSSVGVDVVVVAERMANNVDETYSASDAVQFDAVVVADGAEGLFG 598 Query: 598 ANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGE 657 A+ TV+P A TL GR L+ + +AF K +GA G Sbjct: 599 ADSFTVEPS------------------AGSGASTLYPAGRPLNILLDAFRFGKTVGALGS 640 Query: 658 AVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAGFLGEF 713 D AL +SSE + GV T K ++F +K FL F Sbjct: 641 GSD------ALESGQISSERQ-----GVYTGKNAG-DAFAKDIKSGLSTFKFLDRF 684 >4BIM-A nrPDB Length = 746 Score = 815 bits (2106), Expect = 0.0, Method: Composition-based stats. Identities = 280/731 (38%), Positives = 396/731 (54%), Gaps = 46/731 (6%) Query: 1 MSNIISQAGQKAKEALTSAPSSKKVD---DLKNEFKE---TDKSARLTTDYGVKQTTADD 54 +S +I A A SA + D + KE D +TTD+G + Sbjct: 36 LSGLIGTALAACPFADPSALGRRAEGGEVDARQRLKEVEVDDNGQFMTTDFGGNI----E 91 Query: 55 WLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMA 114 + G +LLED R+++ FDHERIPERVVHARG+GA G F Y S++T A Sbjct: 92 EQFSLKAGGRGSTLLEDFIFRQKLQHFDHERIPERVVHARGAGAHGIFTSYGDWSNITAA 151 Query: 115 PVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQD 174 L ++TPVFVRFSTV GSRGSADT RDV GFA +FYT+EGN+D+VGNNIPVFFIQD Sbjct: 152 SFLGAKDKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQD 211 Query: 175 AIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQ 234 AI+FPD+IH+ KP P NEVPQA +AH++ WDF + A H WAMS IPRS R M Sbjct: 212 AIRFPDLIHSVKPSPDNEVPQAATAHDSAWDFFSSQPSALHTLFWAMSGNGIPRSYRHMD 271 Query: 235 GFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGA 294 GFG++T+ L+ GK VK+HW + G +LVW+EA LAG++ DFHR+DLW+AIE+G Sbjct: 272 GFGIHTFRLVTEDGKSKLVKWHWKTKQGKAALVWEEAQVLAGKNADFHRQDLWDAIESGN 331 Query: 295 YPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIA 354 P W+ +Q I E+ + FD+LD TK PE+ P++ +GEM LNRNP +F +TEQI+ Sbjct: 332 APSWELAVQLIDEDKAQAYGFDLLDPTKFLPEEFAPLQVLGEMTLNRNPMNYFAETEQIS 391 Query: 355 FCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL-GVNFQELPINRPVCPVMNFNRDGAMR 413 F H+V G+ F++DPLLQGR +SY DTQ++R G NF++LPINRPV V N +RDG + Sbjct: 392 FQPGHIVRGVDFTEDPLLQGRLYSYLDTQLNRHRGPNFEQLPINRPVSGVHNNHRDGQGQ 451 Query: 414 HTISRGTVNYYPNRFDACPPASLKE----GGYLEYAQKVAGIKARARSAKFKEHFSQAQL 469 I + +Y P+ + PA + G + + +G+ R SA F +H++Q +L Sbjct: 452 AWIHKNIHHYSPSYLNKGYPAQANQTVGRGFFTTPGRTASGVLNRELSATFDDHYTQPRL 511 Query: 470 FYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMVGGEAPTTT 529 F+NS++P+E+Q +INA FE H + V ++++L I +A+ +A +G EAP Sbjct: 512 FFNSLTPVEQQFVINAIRFEASHVTNEQVKKNVLEQLNKISNDVAKRVAVALGLEAPQPD 571 Query: 530 NHPNHGRKTINLSQTEFPPATPTIKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIG 589 H + + F + PTI + RV ++ + D A A + L + Sbjct: 572 PTYYHNN--VTRGVSIFNESLPTIATLRVGVL--STTKGGSLDKAKALKEQLEKDGLKVT 627 Query: 590 PRRSKVTAANGSTVQPHHHLEGFRSTMVDAIFIPGGAK-------AAETLSKNGRALHWI 642 + + T +T DA+ + GA+ A L GR + Sbjct: 628 VIAEYLASGVDQTYSAAD------ATAFDAVVVAEGAERVFSGKGAMSPLFPAGRPSQIL 681 Query: 643 REAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKI 702 + + K + A G A AL + V + GV + + V+ Sbjct: 682 TDGYRWGKPVAAVGSAKK------ALQSIGVEEK-----EAGVYAGAQ---DEVIKGVEE 727 Query: 703 AKGAAGFLGEF 713 FL F Sbjct: 728 GLKVFKFLERF 738 >2IQF-A nrPDB Length = 505 Score = 711 bits (1836), Expect = 0.0, Method: Composition-based stats. Identities = 202/489 (41%), Positives = 290/489 (59%), Gaps = 9/489 (1%) Query: 35 TDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHAR 94 +K + TT +G D +++ GP LL+ + E++ FD ERIPERVVHA+ Sbjct: 2 VNKDVKQTTAFG---APVWDDNNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAK 58 Query: 95 GSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFY 154 GSGA+G F V + + T A + + ++T F RFSTV G RGSAD VRD RGFA+K+Y Sbjct: 59 GSGAYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYY 118 Query: 155 TEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEAT 214 TEEGNWDLVGNN PVFFI+DAIKFPD IH K +P +P H+ WDF N E+ Sbjct: 119 TEEGNWDLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPN----HDMVWDFWSNVPESL 174 Query: 215 HMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKL 274 + TW MSDR IP+S R M GFG +T++LINA+G+R +VKFH+ GV L +EA ++ Sbjct: 175 YQVTWVMSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEI 234 Query: 275 AGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYI 334 DPD +++DL++AI G YPKWK IQ + EED K+ F D TKIW P+ + Sbjct: 235 RKHDPDSNQRDLFDAIARGDYPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYTQDYPLMEV 294 Query: 335 GEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQEL 394 G +ELN+NP+ +F + EQ AF ++VV GIG+S D +LQGR FSY DT RLGVN+ ++ Sbjct: 295 GIVELNKNPENYFAEVEQAAFTPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQI 354 Query: 395 PINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPP-ASLKEGGY-LEYAQKVAGIK 452 P+N+P CP + +RDG M++ NY P+ S ++ + L + +K + Sbjct: 355 PVNKPRCPFHSSSRDGYMQNGYYGSLQNYTPSSLPGYKEDKSARDPKFNLAHIEKEFEVW 414 Query: 453 ARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLG 512 A ++++Q +Y S+ EK+ + + G L H + + ++ D Sbjct: 415 NWDYRADDSDYYTQPGDYYRSLPADEKERLHDTIGESLAHVTHKEIVDKQLEHFKKADPK 474 Query: 513 LAQTIAEMV 521 A+ + + + Sbjct: 475 YAEGVKKAL 483 >1SI8-A nrPDB Length = 484 Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats. Identities = 188/492 (38%), Positives = 274/492 (55%), Gaps = 18/492 (3%) Query: 37 KSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGS 96 K+ LTT G + D ++ + GP L++D E++ F+ ER+PERVVHA+G+ Sbjct: 2 KNQHLTTSQG---SPVGDNQNSLTAGEFGPVLIQDVHLLEKLAHFNRERVPERVVHAKGA 58 Query: 97 GAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTE 156 GA G FKV +S + T A L++ +ETP+F RFSTV G GS+DT+RD RGFA+KFYT+ Sbjct: 59 GAHGIFKVSQSMAQYTKADFLSEVGKETPLFARFSTVAGELGSSDTLRDPRGFALKFYTD 118 Query: 157 EGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHM 216 EGN+DLVGNN P+FFI+DAIKFPD IH+ K P + ++ WDF + E+ H Sbjct: 119 EGNYDLVGNNTPIFFIRDAIKFPDFIHSQKRNPRTHLKSPEA----VWDFWSHSPESLHQ 174 Query: 217 FTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAG 276 T MSDR IP S R M GFG +T+ +NA G+ FVK+H+ G+ +L A ++AG Sbjct: 175 VTILMSDRGIPLSFRHMHGFGSHTFKWVNAAGEVFFVKYHFKTNQGIKNLESQLAEEIAG 234 Query: 277 QDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGE 336 ++PDFH +DL AIEN +P W +Q I D + D TK + P+ +G Sbjct: 235 KNPDFHIEDLHNAIENQEFPSWTLSVQIIPYADALTMKETLFDVTKTVSQKEYPLIEVGT 294 Query: 337 MELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPI 396 M LNRNP+ +F + EQ+ F + V GI S D LLQGR F+Y D R+G N +LPI Sbjct: 295 MTLNRNPENYFAEVEQVTFSPGNFVPGIEASPDKLLQGRLFAYGDAHRHRVGANSHQLPI 354 Query: 397 NRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARAR 456 N+ PV N+ +DG MR +NY PN + P + K++ + Sbjct: 355 NQAKAPVNNYQKDGNMRFNNGNSEINYEPNSYTETPK--------EDPTAKISSFEVEGN 406 Query: 457 SAKF---KEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGL 513 + ++HF+QA YN + EK+++IN L ++ + R + ++ Sbjct: 407 VGNYSYNQDHFTQANALYNLLPSEEKENLINNIAASLGQVKNQEIIARQIDLFTRVNPEY 466 Query: 514 AQTIAEMVGGEA 525 +A+ + +A Sbjct: 467 GARVAQAIKQQA 478 >5GKN-A nrPDB Length = 527 Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats. Identities = 190/505 (37%), Positives = 277/505 (54%), Gaps = 17/505 (3%) Query: 20 PSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIM 79 P+S ++ K E + K LTT G D L ++ GP L++D + + Sbjct: 7 PASDQMKHWK-EQRAAQKPDVLTTGGG---NPVGDKLNSLTVGPRGPLLVQDVVFTDEMA 62 Query: 80 RFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGS 139 FD ERIPERVVHA+G+GAFG F+V + + A V + TP+ VRFSTV G GS Sbjct: 63 HFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGS 122 Query: 140 ADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSA 199 ADTVRD RGFAVKFYTE+GNWDLVGNN P+FFI+DA+ FP IH+ K P + Sbjct: 123 ADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDP--- 179 Query: 200 HNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTP 259 + WDF E+ H ++ SDR IP R M G+G +T+ L+NA G+ + KFH+ Sbjct: 180 -DMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKT 238 Query: 260 ELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILD 319 + G+ +L ++A +LA +DPD+ +DL+ AI G YP W IQ + + F F+ D Sbjct: 239 DQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFD 298 Query: 320 ATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSY 379 TK+WP P+ +G++ LNRNP +F + EQ+AF S++ GI S D +LQGR F+Y Sbjct: 299 LTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAY 358 Query: 380 FDTQISRLGVNFQELPINRP-VCPVMNFNRDGAMRHTISRGTV-NYYPNRFDACPPASLK 437 DT RLG N+ ++P+N P V N+ RDG M ++G NYYPN F A Sbjct: 359 PDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFS----APEH 414 Query: 438 EGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFY-NSMSPIEKQHMINAFGFELDHCEDP 496 + LE+ +G R SA ++ +Q + FY ++ +++ + L + Sbjct: 415 QPSALEHRTHFSGDVQRFNSAN-DDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQL- 472 Query: 497 VVYGRMVQRLADIDLGLAQTIAEMV 521 + + V+ +D+ I ++ Sbjct: 473 FIQKKAVKNFSDVHPEYGSRIQALL 497 >3HB6-A nrPDB Length = 484 Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats. Identities = 186/488 (38%), Positives = 269/488 (55%), Gaps = 13/488 (2%) Query: 37 KSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGS 96 + +LTT G D +++ GP LL+D + E++ FD E IPER + A+GS Sbjct: 2 EKKKLTTAAG---APVVDNNNVITAGPRGPMLLQDVWFLEKLAHFDREVIPERRMFAKGS 58 Query: 97 GAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTE 156 GAFG F V + T A + ++ ++T +F RFSTV G RG+AD RD+RGFA+KFYTE Sbjct: 59 GAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTE 118 Query: 157 EGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHM 216 EGNWD+VGNN PVF+++D +KFPD+ H K +P + WDF + E+ H Sbjct: 119 EGNWDMVGNNTPVFYLRDPLKFPDLNHIVKRDPRTNMRNMAYK----WDFFSHLPESLHQ 174 Query: 217 FTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAG 276 T MSDR +P S R + GFG +TY+ IN +R +VKFH+ + G+ +L+ DEA L G Sbjct: 175 LTIDMSDRGLPLSYRFVHGFGSHTYSFINKDNERFWVKFHFRCQQGIKNLMDDEAEALVG 234 Query: 277 QDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGE 336 +D + ++DL+EAIE G YP+WK IQ + E++ ++ D TK+WP P+ +G Sbjct: 235 KDRESSQRDLFEAIERGDYPRWKLQIQIMPEKEASTVPYNPFDLTKVWPHADYPLMDVGY 294 Query: 337 MELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPI 396 ELNRNPD +F EQ AF +++V GI FS D +LQGR FSY D RLGVN ++P+ Sbjct: 295 FELNRNPDNYFSDVEQAAFSPANIVPGISFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPV 354 Query: 397 NRPVCPVMNFNRDGAMRHTISRG-TVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARA 455 N P CP N++RDGAMR + G + Y PN ++ + E + G Sbjct: 355 NAPKCPFHNYHRDGAMRVDGNSGNGITYEPNS----GGVFQEQPDFKEPPLSIEGAADHW 410 Query: 456 RSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQ 515 + +++FSQ + Y +S E Q M EL R + + Sbjct: 411 NHREDEDYFSQPRALYELLSDDEHQRMFARIAGELSQA-SKETQQRQIDLFTKVHPEYGA 469 Query: 516 TIAEMVGG 523 + + + Sbjct: 470 GVEKAIKV 477 >1QQW-A nrPDB Length = 527 Score = 693 bits (1788), Expect = 0.0, Method: Composition-based stats. Identities = 193/523 (36%), Positives = 286/523 (54%), Gaps = 18/523 (3%) Query: 15 ALTSAPSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFA 74 A + P+S ++ K E + K+ LTT G D L +++ GP L++D Sbjct: 2 ADSRDPASDQMQHWK-EQRAAQKADVLTTGAG---NPVGDKLNVITVGPRGPLLVQDVVF 57 Query: 75 RERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVL 134 + + FD ERIPERVVHA+G+GAFG F+V + + A V ++TP+ VRFSTV Sbjct: 58 TDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVA 117 Query: 135 GSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVP 194 G GSADTVRD RGFAVKFYTE+GNWDLVGNN P+FFI+D I FP IH+ K P + Sbjct: 118 GESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLK 177 Query: 195 QAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVK 254 + WDF E+ H ++ SDR IP R M G+G +T+ L+NA G+ + K Sbjct: 178 DP----DMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCK 233 Query: 255 FHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFD 314 FH+ + G+ +L ++A +L+ +DPD+ +DL+ AI G YP W F IQ + F Sbjct: 234 FHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFP 293 Query: 315 FDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQG 374 F+ D TK+WP P+ +G++ LNRNP +F + EQIAF S++ GI S D +LQG Sbjct: 294 FNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQG 353 Query: 375 RNFSYFDTQISRLGVNFQELPINRP-VCPVMNFNRDGAMRHTISRGTV-NYYPNRFDACP 432 R F+Y DT RLG N+ +P+N P V N+ RDG M ++G NYYPN F Sbjct: 354 RLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFG--- 410 Query: 433 PASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFY-NSMSPIEKQHMINAFGFELD 491 A ++ LE++ + +G R +A ++ +Q + FY N ++ +++ + L Sbjct: 411 -APEQQPSALEHSIQYSGEVRRFNTAN-DDNVTQVRAFYVNVLNEEQRKRLCENIAGHLK 468 Query: 492 HCEDPVVYGRMVQRLADIDLGLAQTIAEMV-GGEAPTTTNHPN 533 + + + V+ ++ I ++ A N + Sbjct: 469 DAQI-FIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIH 510 >4E37-A nrPDB Length = 484 Score = 691 bits (1783), Expect = 0.0, Method: Composition-based stats. Identities = 176/491 (35%), Positives = 273/491 (55%), Gaps = 14/491 (2%) Query: 37 KSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGS 96 + RLTT G D + + GP LL+D + E++ FD E IPER +HA+GS Sbjct: 1 EKTRLTTAAG---APVVDNQNVQTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS 57 Query: 97 GAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTE 156 A+G F V + T A + + ++T +F+RFSTV G RG+AD RD+RGF+++FYTE Sbjct: 58 AAYGTFTVTHDITPYTRAKIFSQVGKKTDMFLRFSTVAGERGAADAERDIRGFSMRFYTE 117 Query: 157 EGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHM 216 +GNWDLVGNN PVF+++D +KFPD+ H K +P + A WDF + E+ H Sbjct: 118 QGNWDLVGNNTPVFYLRDPLKFPDLNHVVKRDPRTNLRNATFK----WDFFSHLPESLHQ 173 Query: 217 FTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAG 276 T SDR +P+S R + GFG +T++ INA +R +VKFH+ + G+ +L EA ++ Sbjct: 174 LTIDFSDRGLPKSYRHIHGFGSHTFSFINANNERFWVKFHFKTQQGIENLTNAEAAEVIA 233 Query: 277 QDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGE 336 QD + ++DL+E+IE G +P+WK +Q + E++ + ++ D TK+WP P+ +G Sbjct: 234 QDRESSQRDLYESIEKGDFPRWKMYVQIMPEKEAATYRYNPFDLTKVWPHGDYPLIEVGF 293 Query: 337 MELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPI 396 ELNRNPD +F + EQ AF ++VV GIGFS D +LQGR FSY D RLGVN ++P+ Sbjct: 294 FELNRNPDNYFAEVEQAAFTPANVVPGIGFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPV 353 Query: 397 NRPVCPVMNFNRDGAMRHTIS--RGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKAR 454 N CP ++RDG MR + V Y PN F+ ++ + E + G Sbjct: 354 NAARCPHQVYHRDGGMRVDGNNAHQRVTYEPNSFNQW----QEQPDFSEPPLSLEGAADH 409 Query: 455 ARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLA 514 +++SQ ++ + +KQ + ++ + R + +D Sbjct: 410 WNHRVDDDYYSQPAALFHLFTDEQKQRLFANIAEDIRDVP-EQIQRRQIGLFLKVDPAYG 468 Query: 515 QTIAEMVGGEA 525 + +A+ +G + Sbjct: 469 KGVADALGLKL 479 >4QOP-A nrPDB Length = 491 Score = 683 bits (1762), Expect = 0.0, Method: Composition-based stats. Identities = 201/490 (41%), Positives = 277/490 (56%), Gaps = 11/490 (2%) Query: 35 TDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHAR 94 LTT+ GV D + GPS L+D E++ FD ERIPERVVHAR Sbjct: 3 NSNHKNLTTNQGV---PVGDNQNSRTAGHRGPSFLDDYHLIEKLAHFDRERIPERVVHAR 59 Query: 95 GSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFY 154 G+GA+G F+V S T A L++ ++T VFVRFSTV+ +GS +T+RD RGFAVKFY Sbjct: 60 GAGAYGVFEVENSMEKHTRAAFLSEEGKQTDVFVRFSTVIHPKGSPETLRDPRGFAVKFY 119 Query: 155 TEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEAT 214 TEEGN+DLVGNN+P+FFI+DA+KFPD++H+ KP+P + + +WDF E+T Sbjct: 120 TEEGNYDLVGNNLPIFFIRDALKFPDMVHSLKPDPVTNIQDP----DRYWDFMTLTPEST 175 Query: 215 HMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKL 274 HM TW SD IP + M+G GV+T+ +N G+ +VK+HW P G+ +L +EA ++ Sbjct: 176 HMLTWLFSDEGIPANYAEMRGSGVHTFRWVNKYGETKYVKYHWRPSEGIRNLSMEEAAEI 235 Query: 275 AGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYI 334 D +DL++ IE G YP W +Q + D + D+D D TK W E+ P++ + Sbjct: 236 QANDFQHATRDLYDRIEKGNYPAWDLYVQLMPLSDYDELDYDPCDPTKTWSEEDYPLQKV 295 Query: 335 GEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQEL 394 G M LNRNP+ FF +TEQ AF S +V GI S+D LLQGR FSY DTQ RLG N+ + Sbjct: 296 GRMTLNRNPENFFAETEQAAFTPSALVPGIEASEDKLLQGRLFSYPDTQRHRLGANYMRI 355 Query: 395 PINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKAR 454 P+N P PV N +DG M T G +NY PNR+D P + Y E + G + Sbjct: 356 PVNCPYAPVHNNQQDGFMTTTRPSGHINYEPNRYDDQPKENPH---YKESEPVLHGDRMV 412 Query: 455 ARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLA 514 + + F QA Y S S EKQ +I +L + + D Sbjct: 413 RQKIEKPNDFKQAGEKYRSYSEEEKQALIKNLTADLKGV-NEKTKLLAICNFYRADEDYG 471 Query: 515 QTIAEMVGGE 524 Q +A+ +G + Sbjct: 472 QRLADSLGVD 481 >2ISA-A nrPDB Length = 483 Score = 678 bits (1748), Expect = 0.0, Method: Composition-based stats. Identities = 190/494 (38%), Positives = 281/494 (56%), Gaps = 13/494 (2%) Query: 38 SARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSG 97 S +LTT G + + K GP LL+D + E++ FD E IPER +HA+GSG Sbjct: 2 SKKLTTAAGC---PVAHNQNVQTAGKRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSG 58 Query: 98 AFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEE 157 A+G F V + T A + +D ++T +F RFSTV G RG+AD RD+RGF++KFYTEE Sbjct: 59 AYGTFTVTHDITKYTKAKIFSDIGKKTDMFARFSTVAGERGAADAERDIRGFSLKFYTEE 118 Query: 158 GNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMF 217 GNWDL GNN PVFF++D +KFPD+ HA K +P + A++ WDF + EA H Sbjct: 119 GNWDLAGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAKNN----WDFWTSLPEALHQV 174 Query: 218 TWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQ 277 T MSDR IP + R M GFG +T++ IN+ +R++VKFH+ + G+ +L EA +L G Sbjct: 175 TIVMSDRGIPATYRHMHGFGSHTFSFINSDNERYWVKFHFVSQQGIKNLSDAEAGELVGN 234 Query: 278 DPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEM 337 D + H++DL ++I+N +PKW +Q + E D ++ D TK+WP P+ +GE Sbjct: 235 DRESHQRDLLDSIDNQDFPKWTLKVQIMPEADAATVPYNPFDLTKVWPHKDYPLIEVGEF 294 Query: 338 ELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPIN 397 ELNRNP +F + EQ AF ++VV GI FS D +LQGR F+Y D Q RLGVN Q +P+N Sbjct: 295 ELNRNPQNYFAEVEQAAFNPANVVPGISFSPDKMLQGRLFAYGDAQRYRLGVNHQHIPVN 354 Query: 398 RPVCPVMNFNRDGAMRHTISRG-TVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARAR 456 P CPV +++RDGAMR + G T+ Y PN ++ + E + G A Sbjct: 355 APRCPVHSYHRDGAMRVDGNFGSTLGYEPNDQGQW----AEQPDFSEPPLNLDGAAAHWD 410 Query: 457 SAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQT 516 + +++FSQ + M+ ++ + + L+ + R V D + Sbjct: 411 HREDEDYFSQPGDLFGLMTAEKQAILFDNTARNLNGVP-KEIQLRHVTHCYKADPAYGEG 469 Query: 517 IAEMVGGEAPTTTN 530 I +++G + + Sbjct: 470 IGKLLGFDISEYNS 483 >2J2M-A nrPDB Length = 491 Score = 668 bits (1722), Expect = 0.0, Method: Composition-based stats. Identities = 197/490 (40%), Positives = 276/490 (56%), Gaps = 10/490 (2%) Query: 35 TDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHAR 94 + +LTT+ GV D + + GP+LLED E+I FD ER+PERVVHAR Sbjct: 2 NENEKKLTTNQGV---PIGDNQNSRTAGRRGPTLLEDYQLIEKIAHFDRERVPERVVHAR 58 Query: 95 GSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFY 154 G GA G FKV S T A L + E PVF RFSTV+ S +T+RD RGF+VKFY Sbjct: 59 GFGAHGVFKVKNSMKKYTKAAFLQEEGTEVPVFARFSTVIHGTHSPETLRDPRGFSVKFY 118 Query: 155 TEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEAT 214 TEEGNWD VGNN+PVFFI+DA+KFPD++H+ KP+P + + +WDF E+T Sbjct: 119 TEEGNWDFVGNNLPVFFIRDAMKFPDMVHSLKPDPRTNIQDP----DRYWDFMTLRPEST 174 Query: 215 HMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKL 274 +M +D IP S R M+G V+++ +NA G ++K W P+ GVH+L DEA ++ Sbjct: 175 NMLMHIFTDEGIPASYRKMRGSSVHSFKWVNAHGNTVYIKLRWVPKEGVHNLSADEATEV 234 Query: 275 AGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYI 334 G+D + D ++AIENG +P+W +Q + D FDFD LDATK W ED++P +++ Sbjct: 235 QGKDFNHASNDTFQAIENGDFPEWDLFVQVLDPADVENFDFDPLDATKDWFEDVIPFQHV 294 Query: 335 GEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQEL 394 G M LN+N D +F +TE + F +V G+ S+D LLQGR FSY DTQ R+G N+Q+L Sbjct: 295 GTMTLNKNVDNYFAETESVGFNPGVLVPGMLPSEDKLLQGRLFSYSDTQRHRIGPNYQQL 354 Query: 395 PINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKAR 454 PIN P V N+ RDGAM +VNY PNR+ P + + Y E Q + Sbjct: 355 PINCPFAQVNNYQRDGAMPFKQQTSSVNYEPNRYQDEPKQTPE---YTEDTQPLHDDIHG 411 Query: 455 ARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLA 514 + +F QA Y M+ E+ ++N +L + D L Sbjct: 412 RLEIEKTNNFGQAGEVYRRMTEEEQMALLNNLVNDLQQVRHENTVLLAICNFYRADASLG 471 Query: 515 QTIAEMVGGE 524 + ++E + + Sbjct: 472 EKLSEALNVD 481 >4CAB-A nrPDB Length = 536 Score = 636 bits (1641), Expect = 0.0, Method: Composition-based stats. Identities = 198/496 (39%), Positives = 272/496 (54%), Gaps = 22/496 (4%) Query: 36 DKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARG 95 ++ LTT G D + GP LE+ E++ FD ERIPERVVHARG Sbjct: 28 EQGTTLTTRQG---HPVHDNQNSRTVGSRGPMTLENYQFIEKLSHFDRERIPERVVHARG 84 Query: 96 SGAFGKFKVY-----ESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFA 150 GA G F+ E S T A + + +ETPVFVRFSTV S +T+RD RGFA Sbjct: 85 VGAHGVFRATGKVGDEPVSKYTRAKLFQEDGKETPVFVRFSTVGHGTHSPETLRDPRGFA 144 Query: 151 VKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNH 210 VKFYTE+GNWDLVGNN+ +FFI+DA+KFPD+IH+ KP P + + +DF Sbjct: 145 VKFYTEDGNWDLVGNNLKIFFIRDALKFPDLIHSQKPSPTTNIQ----SQERIFDFFAGS 200 Query: 211 TEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDE 270 EATHM T S IP S R MQG GVNTY +N QG+ VK+HW P GV +L + Sbjct: 201 PEATHMITLLYSPWGIPASYRFMQGSGVNTYKWVNDQGEGVLVKYHWEPVQGVRNLTQMQ 260 Query: 271 ALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVP 330 A ++ + + +DL +AIE G +P+W +Q + + + + DFD LD TKIWP + P Sbjct: 261 ADEVQATNFNHATQDLHDAIERGDFPQWDLFVQIMEDGEHPELDFDPLDDTKIWPREQFP 320 Query: 331 VRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVN 390 R++G+M LNRNP+ F +TEQ AF T +V+G+ FSDD +LQGR FSY DTQ R+G N Sbjct: 321 WRHVGQMTLNRNPENVFAETEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGPN 380 Query: 391 FQELPINRPVCPVMNFNRDGAMRHTISR-----GTVNYYPNRFDACPPASLKEGGYLEYA 445 + +LPIN P V RDG M + + VNY P+ A + E+ Sbjct: 381 YLQLPINAPKKHVATNQRDGQMAYRVDTFEGQDQRVNYEPSLLSGPKEAPRRAP---EHT 437 Query: 446 QKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQR 505 +V G RA + + F QA + Y + + E+ +++ L D + +M++ Sbjct: 438 PRVEGNLVRA-AIERPNPFGQAGMQYRNFADWERDELVSNLSGALAGV-DKRIQDKMLEY 495 Query: 506 LADIDLGLAQTIAEMV 521 D Q + E + Sbjct: 496 FTAADADYGQRVREGI 511 >2XQ1-A nrPDB Length = 509 Score = 631 bits (1627), Expect = 0.0, Method: Composition-based stats. Identities = 185/510 (36%), Positives = 265/510 (51%), Gaps = 20/510 (3%) Query: 37 KSARLTTDYGVKQTTADDWLRI-------VSDDKIGPSLLEDPFARERIMRFDHERIPER 89 TT G + RI IGP LL+D + + FD ERIPER Sbjct: 5 NPPVFTTSQGCPVSDPFTTQRIPLDSTGYKYAPPIGPLLLQDFKLIDTLSHFDRERIPER 64 Query: 90 VVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGF 149 VVHA+G+GA+G F+V + +D+ A L ++T +F RFSTV G +GSADT RD RGF Sbjct: 65 VVHAKGAGAYGVFEVTDDITDVCSAKFLDTVGKKTRIFTRFSTVGGEKGSADTARDPRGF 124 Query: 150 AVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFN 209 A KFYTE+GN DLV NN P+FFI+D IKFP IH K P + N FWD+ Sbjct: 125 ATKFYTEDGNLDLVYNNTPIFFIRDPIKFPHFIHTQKRNPATNLKDP----NMFWDYLTA 180 Query: 210 HTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWD 269 + E+ H + S+R P S R M G+ +TY N++G+ +V+ H+ GVH+L+ + Sbjct: 181 NDESLHQVMYLFSNRGTPASYRTMNGYSGHTYKWYNSKGEWVYVQVHFIANQGVHNLLDE 240 Query: 270 EALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLV 329 EA +LAG+DPD +DLWEAIE G YP W+ IQ + E K F + D TK+WP Sbjct: 241 EAGRLAGEDPDHSTRDLWEAIEKGDYPSWECYIQTMTLEQSKKLPFSVFDLTKVWPHKDF 300 Query: 330 PVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGV 389 P+R+ G LN NP ++ +TEQIAF SH V G+ S+DP+LQ R FSY DT RLG Sbjct: 301 PLRHFGRFTLNENPKNYYAETEQIAFSPSHTVPGMEPSNDPVLQSRLFSYPDTHRHRLGP 360 Query: 390 NFQELPINRPVC--PVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYL--EYA 445 N+ ++P+N P+ NRDG M + G Y N ++ CP + Sbjct: 361 NYHQIPVNCPLKSGSFNPINRDGPMCVDGNLGGTPNYANAYN-CPIQYAVSPKASGNKPD 419 Query: 446 QKVAGIKARARSAKFKEHFSQAQLFYNSM--SPIEKQHMINAFGFELDHCEDPVVYGRMV 503 +K G + Q ++F+ + +P E++ ++ + D + R+ Sbjct: 420 EKYTGEVVPYHWEHTDYDYFQPKMFWKVLGRTPGEQESLVKNVANHVSAA-DEFIQDRVY 478 Query: 504 QRLADIDLGLAQTIAEMVGGEAPTTTNHPN 533 + + + + I + V E + P+ Sbjct: 479 EYFSKAEPIIGDLIRKKV-QELKRKASSPS 507 >1A4E-A nrPDB Length = 488 Score = 607 bits (1564), Expect = e-174, Method: Composition-based stats. Identities = 175/499 (35%), Positives = 250/499 (50%), Gaps = 31/499 (6%) Query: 37 KSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGS 96 + +T G ++ + GP LL+D + + F+ E IP+R HA GS Sbjct: 4 EDRVVTNSTG---NPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS 60 Query: 97 GAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTE 156 GAFG F+V + +D+ + + + + T RFSTV G +GSADTVRD RGFA KFYTE Sbjct: 61 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE 120 Query: 157 EGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFN--HTEAT 214 EGN D V NN PVFFI+D KFP IH K P + A + FWDF + A Sbjct: 121 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTPENQVAI 176 Query: 215 HMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKL 274 H SDR P + R M G+ +TY N G H+V+ H + G+ +L +EA K+ Sbjct: 177 HQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKI 236 Query: 275 AGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYI 334 AG +PD+ ++DL+EAI+NG YP W IQ + E D K F + D TK+WP+ P+R + Sbjct: 237 AGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRV 296 Query: 335 GEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQEL 394 G++ LN NP FF Q EQ AF S V S DP+LQ R FSY D RLG NF ++ Sbjct: 297 GKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQI 356 Query: 395 PINRPVCP--VMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIK 452 P+N P RDG M + G+ Y A+ K Y++ + + + Sbjct: 357 PVNCPYASKFFNPAIRDGPMNVNGNFGSEPTY--------LANDKSYTYIQQDRPIQQHQ 408 Query: 453 ARARSAKFKEH---------FSQAQLFYNSM--SPIEKQHMINAFGFELDHCEDPVVYGR 501 H F QA+ Y + P +++++ G ++ P + R Sbjct: 409 EVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGAC-PQIQQR 467 Query: 502 MVQRLADIDLGLAQTIAEM 520 + A +D GL++ I ++ Sbjct: 468 VYDMFARVDKGLSEAIKKV 486 >1M7S-A nrPDB Length = 484 Score = 605 bits (1559), Expect = e-173, Method: Composition-based stats. Identities = 200/490 (40%), Positives = 271/490 (55%), Gaps = 16/490 (3%) Query: 38 SARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSG 97 + LT D G D + GP LL+D +++ RFD ERIPERVVHARG+G Sbjct: 1 TDTLTRDNG---AVVGDNQNSQTAGAQGPVLLQDVQLLQKLQRFDRERIPERVVHARGTG 57 Query: 98 AFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEE 157 G+F SDL+ A V + +TPVFVRFS+V+ S +T+RD GFA KFYT + Sbjct: 58 VKGEFTASADISDLSKATVF-KSGEKTPVFVRFSSVVHGNHSPETLRDPHGFATKFYTAD 116 Query: 158 GNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMF 217 GNWDLVGNN P FFI+DAIKFPD++HA KP+P + + +DF + EAT Sbjct: 117 GNWDLVGNNFPTFFIRDAIKFPDMVHAFKPDPRTNL----DNDSRRFDFFSHVPEATRTL 172 Query: 218 TWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQ 277 T S+ P R M G GV+ Y L+NA+G+ H+VKFHW G+ +L E ++ + Sbjct: 173 TLLYSNEGTPAGYRFMDGNGVHAYKLVNAKGEVHYVKFHWKSLQGIKNLDPKEVAQVQSK 232 Query: 278 DPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEM 337 D DL AI+ G +PKW +Q + E+ KFDFD LDATKIWP VP + IG+M Sbjct: 233 DYSHLTNDLVGAIKKGDFPKWDLYVQVLKPEELAKFDFDPLDATKIWP--DVPEKKIGQM 290 Query: 338 ELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPIN 397 LN+N D FF +TEQ+A +++V GI S+D LLQGR FSY DTQ+ RLG N LP+N Sbjct: 291 VLNKNVDNFFQETEQVAMAPANLVPGIEPSEDRLLQGRVFSYADTQMYRLGANGLSLPVN 350 Query: 398 RPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARARS 457 +P V N N+DGA+ + VNY P+R + P L ++G +A+ Sbjct: 351 QPKVAVNNGNQDGALNTGHTTSGVNYEPSRLEPRPADDKARYSEL----PLSGTTQQAKI 406 Query: 458 AKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTI 517 + +++F QA Y S S EK ++ FG L M+ L D + Sbjct: 407 TR-EQNFKQAGDLYRSYSAKEKTDLVQKFGESLAD-TLTESKNIMLSYLYKEDPNYGTRV 464 Query: 518 AEMVGGEAPT 527 AE+ G+ Sbjct: 465 AEVAKGDLSK 474 >4B7G-A nrPDB Length = 515 Score = 592 bits (1526), Expect = e-169, Method: Composition-based stats. Identities = 166/487 (34%), Positives = 250/487 (51%), Gaps = 23/487 (4%) Query: 50 TTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESAS 109 + GP++L D E++ F+ E +PER+ HA+G GAFG+ + E S Sbjct: 28 APVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGELHITEDVS 87 Query: 110 DLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPV 169 + T A + + TP+ VRFSTV G +GS DT RDV GFA++FYTEEGN+D+VGNN P Sbjct: 88 EYTKADLFQ-PGKVTPLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIVGNNTPT 146 Query: 170 FFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRS 229 FF++D +KFPD IH+ K N + A + WDF E+ H T+ M DR P++ Sbjct: 147 FFLRDGMKFPDFIHSQKRLNKNGLRDA----DMQWDFWTRAPESAHQVTYLMGDRGTPKT 202 Query: 230 LRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEA 289 R GFG +T+ INA+GK +VK+H+ G EA K+AG++ D+ R+DL+ A Sbjct: 203 SRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCFTDAEAAKVAGENADYQREDLYNA 262 Query: 290 IENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQ 349 IENG +P W +Q + ED + ++ D TK W + P+ +G LNRNP FF Q Sbjct: 263 IENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPRNFFAQ 322 Query: 350 TEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRD 409 EQIA ++V G+G S D +LQ R F+Y D Q R+G N+++LP+NRP+ V ++R+ Sbjct: 323 IEQIALDPGNIVPGVGLSPDRMLQARIFAYADQQRYRIGANYRDLPVNRPINEVNTYSRE 382 Query: 410 GAMRHTIS-RGTVNYYPNRFDACPPASLKEGGYLE---------------YAQKVAGIKA 453 G+M++ G +Y PNR+D ++A Sbjct: 383 GSMQYIFDAEGEPSYSPNRYDKGAGYLDNGTDSSSNHTSYGQADDIYVNPDPHGTDLVRA 442 Query: 454 RARSAKFKEHFSQAQLFYN-SMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLG 512 + + F Q + Y + EK+ + + + R+ ++D Sbjct: 443 AYVKHQDDDDFIQPGILYREVLDEGEKERLADNISNAMQGI-SEATEPRVYDYWNNVDEN 501 Query: 513 LAQTIAE 519 L + E Sbjct: 502 LGARVKE 508 >1GWF-A nrPDB Length = 503 Score = 582 bits (1499), Expect = e-166, Method: Composition-based stats. Identities = 181/486 (37%), Positives = 253/486 (52%), Gaps = 12/486 (2%) Query: 40 RLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAF 99 T A + ++ GP +L D E F+ IPER HA+GSGAF Sbjct: 9 HATGSTRQNGAPAVSDRQSLTVGSEGPIVLHDTHLLETHQHFNRMNIPERRPHAKGSGAF 68 Query: 100 GKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGN 159 G+F+V E S T A V +T +RFSTV G GS DT RDVRGFA++FYTEEGN Sbjct: 69 GEFEVTEDVSKYTKALVFQ-PGTKTETLLRFSTVAGELGSPDTWRDVRGFALRFYTEEGN 127 Query: 160 WDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTW 219 +DLVGNN P+FF++D +KF I + K P + + A WDF N+ E+ H T+ Sbjct: 128 YDLVGNNTPIFFLRDPMKFTHFIRSQKRLPDSGLRDATMQ----WDFWTNNPESAHQVTY 183 Query: 220 AMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDP 279 M R +PR+ R M G+G +TY +NAQG++H+VK+H+ + GVH+L DEA K+AG++ Sbjct: 184 LMGPRGLPRTWREMNGYGSHTYLWVNAQGEKHWVKYHFISQQGVHNLSNDEATKIAGENA 243 Query: 280 DFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMEL 339 DFHR+DL+E+I G +PKW IQAI E+ + F+ D TK + P +G + L Sbjct: 244 DFHRQDLFESIAKGDHPKWDLYIQAIPYEEGKTYRFNPFDLTKTISQKDYPRIKVGTLTL 303 Query: 340 NRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRP 399 NRNP+ F Q E AF S+ V GIG S D +L GR F+Y D Q+ R+G + +LP+NRP Sbjct: 304 NRNPENHFAQIESAAFSPSNTVPGIGLSPDRMLLGRAFAYHDAQLYRVGAHVNQLPVNRP 363 Query: 400 VCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARARSA- 458 V N+ +G M + + Y PN E G ++ + G R A Sbjct: 364 KNAVHNYAFEGQMWYDHTGDRSTYVPNSNGDSWSD---ETGPVDDGWEADGTLTREAQAL 420 Query: 459 -KFKEHFSQAQLFYN-SMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQT 516 + F QA S E+ + L V R + ++D + Q Sbjct: 421 RADDDDFGQAGTLVREVFSDQERDDFVETVAGALKGV-RQDVQARAFEYWKNVDATIGQR 479 Query: 517 IAEMVG 522 I + V Sbjct: 480 IEDEVK 485 >1YE9-A nrPDB Length = 226 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 136/224 (60%), Positives = 161/224 (71%), Gaps = 3/224 (1%) Query: 41 LTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFG 100 LTT+ GV+ + LR GP+LLED RE+I FDHERIPER+VHARGS A G Sbjct: 6 LTTNQGVRIADDQNSLR---AGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHG 62 Query: 101 KFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNW 160 F+ Y+S SD+T A L+D ++ TPVFVRFSTV G GSADTVRD+RGFA KFYTEEG + Sbjct: 63 YFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIF 122 Query: 161 DLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWA 220 DLVGNN P+FFIQDA KFPD +HA KPEPH +PQ QSAH+ FWD+ E H WA Sbjct: 123 DLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWA 182 Query: 221 MSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVH 264 MSDR IPRS R M+GFG++T+ LINA+GK FV+FHW P G Sbjct: 183 MSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKA 226 >1YE9-E nrPDB Length = 259 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 134/259 (51%), Positives = 173/259 (66%), Gaps = 5/259 (1%) Query: 273 KLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVR 332 KL G+DPDFHR++LWEAIE G +P+++ G Q I EEDE KFDFD+LD TK+ PE+LVPV+ Sbjct: 1 KLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQ 60 Query: 333 YIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL-GVNF 391 +G+M LNRNPD FF + EQ AF H+V G+ F++DPLLQGR FSY DTQISRL G NF Sbjct: 61 RVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNF 120 Query: 392 QELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDA----CPPASLKEGGYLEYAQK 447 E+PINRP CP NF RDG R I NY PN + P K GG+ Y ++ Sbjct: 121 HEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQER 180 Query: 448 VAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLA 507 V G K R RS F E++S +LF+ S +P E++H+++ F FEL P + R+V +LA Sbjct: 181 VEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLA 240 Query: 508 DIDLGLAQTIAEMVGGEAP 526 IDL LAQ +A+ +G E Sbjct: 241 HIDLTLAQAVAKNLGIELT 259 >3E4Y-A nrPDB Length = 320 Score = 306 bits (784), Expect = 2e-83, Method: Composition-based stats. Identities = 74/303 (24%), Positives = 118/303 (38%), Gaps = 23/303 (7%) Query: 89 RVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRG 148 R +HA+G+ G F A L+ AP L ++ P +RFS G+ D VRG Sbjct: 32 RALHAKGTLYRGTFTATRDAVMLSAAPHLDGST--VPALIRFSNGSGNPKQRDGAPGVRG 89 Query: 149 FAVKFYTEEGNWDLVGNNIPVFFIQDAIK-FPDVIHAGKPEPHNEVPQAQSAHNNFWDFQ 207 AVKF +G+ V + + F D++ A + P P + H Sbjct: 90 MAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMR--PGLTTPLRLATH------L 141 Query: 208 FNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLV 267 H IP S + G++ + I A G FV++H P L Sbjct: 142 LTHPRLLGALPLLREANRIPASYATTEYHGLHAFRWIAADGSARFVRYHLVPTAAEEYLS 201 Query: 268 WDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPED 327 +A G+DPDF +L +++G ++ F +Q D +D + W Sbjct: 202 ASDA---RGKDPDFLTDELAARLQDGPV-RFDFRVQIAGPTDS------TVDPSSAWQS- 250 Query: 328 LVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRL 387 + +G + + E + + F V +GI SDDP+L+ R Y + R Sbjct: 251 -TQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRT 309 Query: 388 GVN 390 GV+ Sbjct: 310 GVD 312 >1U5U-A nrPDB Length = 374 Score = 59.8 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 51/293 (17%), Positives = 95/293 (32%), Gaps = 46/293 (15%) Query: 89 RVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRG 148 R H G+G G+ + T R P +R + + + D D R Sbjct: 64 RATHTVGTGGIGEITIVND-PKFPEHEFFTA-GRTFPARLRHANL---KYPDDAGADARS 118 Query: 149 FAVKF--YTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDF 206 F++KF +G D+V N ++ D + P E A+ + Sbjct: 119 FSIKFADSDSDGPLDIVMNTGEANIFWNSPSLEDFV------PVEEGDAAEEYVYKNPYY 172 Query: 207 QFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFH-------WTP 259 +N EA R P + + + T GK + ++ Sbjct: 173 YYNLVEAL---------RRAPDTFAHLYYYSQVTMPFKAKDGKVRYCRYRALPGDVDIKE 223 Query: 260 ELGVHSLVWDEALKL----AGQDP----DFHRKDLWEAIENGAYPKWKFGIQA--IAEED 309 E L +E K+ ++ D+ RK+ E ++ G ++ IQ + +D Sbjct: 224 EDESGRLTEEEQRKIWIFSRHENEKRPDDYLRKEYVERLQKGPV-NYRLQIQIHEASPDD 282 Query: 310 EHKFDFDILDATKIWPEDLVPVRYIGEMELNRN--PDEFFPQTEQIAFCTSHV 360 I A +W ++ P + ++ + PD IA + + Sbjct: 283 TAT----IFHAGILWDKETHPWFDLAKVSIKTPLSPDVLEKTAFNIANQPASL 331 >2VRN-A nrPDB Length = 190 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Query: 552 TIKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGST-----VQPH 606 + +++AI+ ADG + + + AAI A +I ++ + G + Sbjct: 6 DLTGKKIAILAADGVEEIELTSPRAAIEAAGGTTELISLEPGEIQSMKGDIEPQEKYRVD 65 Query: 607 HHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGA 654 H + + + D + +PGG + L A+ ++R+ + K I A Sbjct: 66 HVVSEVQVSDYDGLLLPGGTVNPDKLRLEEGAMKFVRDMYDAGKPIAA 113 >1G2I-A nrPDB Length = 166 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 45/113 (39%), Gaps = 1/113 (0%) Query: 556 RRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRST 615 +V + A+ +++V Y + + R +T +G +V+ + Sbjct: 1 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPE 60 Query: 616 MVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIAL 668 DA+ +P G +A E + N +A+ R+ F K + + ++ A L Sbjct: 61 EFDALVLP-GGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVL 112 >3L18-A nrPDB Length = 168 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 46/115 (40%), Gaps = 1/115 (0%) Query: 554 KSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFR 613 S +V + ADG++++ I V +R K+T +G +V E Sbjct: 1 ASMKVLFLSADGFEDLELIYPLHRIKEEGHEVYVASFQRGKITGKHGYSVNVDLTFEEVD 60 Query: 614 STMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIAL 668 DA+ +P G KA E + N +A+ R F K + + ++ A L Sbjct: 61 PDEFDALVLP-GGKAPEIVRLNEKAVMITRRMFEDDKPVASICHGPQILISAKVL 114 >2W8Z-A nrPDB Length = 470 Score = 35.1 bits (79), Expect = 0.097, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 43/129 (33%), Gaps = 30/129 (23%) Query: 147 RGFA-VKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGK----PEPHNEVPQAQSAHN 201 +GFA +K +EE NW+L +I + F I + K +P + Sbjct: 337 QGFAQMKAASEEYNWNLRYGDIAMIFRGGCIIRAQFLQKIKEAYDRDPALS---NLLLDS 393 Query: 202 NFWDFQFNHTEATHMFTWAMSDRAIP-----------RSLRMM-----------QGFGVN 239 F D + +A + R IP S R FG + Sbjct: 394 YFKDIVERYQDALREIVATAAMRGIPVPGSASALAYYDSYRTAVLPANLIQAQRDYFGAH 453 Query: 240 TYTLINAQG 248 TY ++ +G Sbjct: 454 TYERVDKEG 462 >4K2H-A nrPDB Length = 188 Score = 34.4 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 27/168 (16%), Positives = 55/168 (32%), Gaps = 7/168 (4%) Query: 556 RRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSK-VTAANGSTVQPHHHLEGFRS 614 ++VA+++A G++ + + S+ V + + + L + Sbjct: 5 KKVAVLLAPGFEEAEAIVTLDILRRLHIDVETLACAESRAVVSYHDIPMVADSTLSERQQ 64 Query: 615 TMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVT-- 672 + DA+ +PGG + + L+ N + ++ K I A V A L + Sbjct: 65 ALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPIASAAARVLGAHGLLKGRRY 124 Query: 673 -VSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQ 719 S + GV V + + KG A+ Sbjct: 125 VCSGDLWKAVPEGVYVDAPVVEDG---NLISGKGLGHVFDFALTLSAR 169 >4O8M-A nrPDB Length = 346 Score = 34.0 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 15/113 (13%), Positives = 41/113 (36%), Gaps = 13/113 (11%) Query: 448 VAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFE-------LDHCEDP--VV 498 VA K F F+N+++P +++ +++A ++ E+ Sbjct: 223 VAKNLNLTAHTKHMSPFVAGTAFWNNLTPEQQKIIVDASREMVTYGGGLIEQAENEALEN 282 Query: 499 YGRMVQRLADID-LGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPAT 550 + + D+D ++A+++ P + + K + ++F Sbjct: 283 LKKAGVTVNDVDLPAFEASVADVISTGFPEWSPNLY---KNVQEKLSQFAENL 332 >3NVQ-A nrPDB Length = 590 Score = 33.6 bits (75), Expect = 0.28, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 60/205 (29%), Gaps = 27/205 (13%) Query: 70 EDPFARERIMRFDHERIPERVVHA-----------RG-SGAFGKFKVYESASDLTMAPVL 117 +D ++I F E P++ A RG G V + + A ++ Sbjct: 188 QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSK-WNTFLKAMLV 246 Query: 118 TDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLV-----GNNIPVFFI 172 + F R V + RD R + V ++ N+ V G+ VF Sbjct: 247 CSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGV--FSNPWNYSAVCVYSLGDIDKVFRT 304 Query: 173 QDAIKFPDVIHAGKPEPHNE--VPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSL 230 + H+ P P +P Q + H E M P Sbjct: 305 SSLKGY----HSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVE-PMGPLKTPLFH 359 Query: 231 RMMQGFGVNTYTLINAQGKRHFVKF 255 V + + + G+ V + Sbjct: 360 SKYHYQKVAVHRMQASHGETFHVLY 384 >5U5I-A nrPDB Length = 278 Score = 32.4 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 19/48 (39%), Gaps = 2/48 (4%) Query: 205 DFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHF 252 DF+ E M+ +P + + G +TY +I+ G F Sbjct: 185 DFKDEQVELVRDPKEQMTRMGVPE--QHLNGHAFHTYKIISPDGTVFF 230 >1Y11-A nrPDB Length = 407 Score = 32.4 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 41/150 (27%), Gaps = 8/150 (5%) Query: 496 PVVYGRMVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKT---INLSQTEFPPATPT 552 V R + +DL L Q + VG + H R +Q Sbjct: 65 TYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEAAARAQRFVELGLNP 124 Query: 553 IKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQ-----PHH 607 + V ++A+G + A Y A+ A A V Sbjct: 125 DQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATELDIAKGSQALVSQIVPLLGPMIQD 184 Query: 608 HLEGFRSTMVDAIFIPGGAKAAETLSKNGR 637 L M++ + G +AA R Sbjct: 185 MLFMQLRHMMETEAVNAGERAAGKPLPGAR 214 >4OUA-B nrPDB Length = 557 Score = 32.4 bits (72), Expect = 0.71, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 53/159 (33%), Gaps = 26/159 (16%) Query: 171 FIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSL 230 F++D F I A + + + + + H + A P+ Sbjct: 21 FVRDEKFFTLYIRALQ-----AIQDKDQSDYSSFFQLSG----IHGLP--FTPWAKPKDT 69 Query: 231 RMM---QGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLW 287 + G+ ++ + F +H + ++ + EA K + H+K+ Sbjct: 70 PTVPYESGYCTHS--------QVLFPTWH-RVYVSIYEQILQEAAKGIAKKFTVHKKEWA 120 Query: 288 EAIENGAYPKWKFGIQAIAEED---EHKFDFDILDATKI 323 +A E+ P W G + ++ + D TKI Sbjct: 121 QAAEDLRQPYWDTGFALVPPDEIIKLEQVKITNYDGTKI 159 >1QMG-A nrPDB Length = 524 Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 38/109 (34%), Gaps = 2/109 (1%) Query: 605 PHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIR-EAFGHLKAIGATGEAVDLVA 663 P F S++ + E + + GR L + +AF +K IG G A Sbjct: 10 PSATTFDFDSSVFKKEKVTLSGH-DEYIVRGGRNLFPLLPDAFKGIKQIGVIGWGSQAPA 68 Query: 664 KAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAGFLGE 712 +A L ++++V G+ E+ G G + E Sbjct: 69 QAQNLKDSLTEAKSDVVVKIGLRKGSNSFAEARAAGFSEENGTLGDMWE 117 >6BHF-A nrPDB Length = 299 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 5/125 (4%) Query: 8 AGQKAKEALTSAPSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPS 67 A ++A+E K++ D N K+ + + T D+ RI+S+ P Sbjct: 123 AKKQAEEVKKVQIPEKEMQDFYNANKDQLFVKQEAHARHILVKTEDEAKRIISEIDKQPK 182 Query: 68 LLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTS--RETP 125 ++ E + + + I +A+ G GKF+ + A D + A +TP Sbjct: 183 AKKEAKFIE-LA--NRDTIDPNSKNAQNGGDLGKFQKNQMAPDFSKAAFALTPGDYTKTP 239 Query: 126 VFVRF 130 V F Sbjct: 240 VKTEF 244 >5EZ1-A nrPDB Length = 277 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 5/125 (4%) Query: 8 AGQKAKEALTSAPSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPS 67 A ++A+E K++ D N K+ + + T D+ RI+S+ P Sbjct: 93 AKKQAEEVKKVQIPEKEMQDFYNANKDQLFVKQEAHARHILVKTEDEAKRIISEIDKQPK 152 Query: 68 LLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTS--RETP 125 ++ E + + + I +A+ G GKF+ + A D + A +TP Sbjct: 153 AKKEAKFIE-LA--NRDTIDPNSKNAQNGGDLGKFQKNQMAPDFSKAAFALTPGDYTKTP 209 Query: 126 VFVRF 130 V F Sbjct: 210 VKTEF 214 >2J63-A nrPDB Length = 467 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 35/100 (35%), Gaps = 6/100 (6%) Query: 212 EATHMF-TWAMSDRAIPRSLRMMQGFGVNTYTLINAQG--KRHFVKFH---WTPELGVHS 265 E H TWA + A+P + M G + + +R + +++ + Sbjct: 320 EYLHRLDTWATENAAVPSAAAMGSGSSPHGFIWAGDLNVAERDYDRYYAGTFKSMQECSG 379 Query: 266 LVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAI 305 +E + + D++ + A P + F Q I Sbjct: 380 FAPEERMSFRETMQRTNSVDIFRQLYPQAGPVYSFWSQRI 419 >1U10-A nrPDB Length = 255 Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 25/81 (30%), Gaps = 5/81 (6%) Query: 207 QFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSL 266 + M T + D +P R G + L + K WT L Sbjct: 62 LSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGL-DVDIFLQLPKTRWTSAQ----L 116 Query: 267 VWDEALKLAGQDPDFHRKDLW 287 + +AL L +D LW Sbjct: 117 LRPQALDLVSRDGKHVVSTLW 137 >2DIE-A nrPDB Length = 485 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 16/39 (41%), Gaps = 4/39 (10%) Query: 357 TSHVVNGIGFSDDPLLQGR-NFSYFDTQISRLGVNFQEL 394 +H V + DPLLQ R ++Y + ++ Sbjct: 375 PTHGVPSMKSKIDPLLQARQTYAYGTQHDY---FDHHDI 410 >3FAW-A nrPDB Length = 877 Score = 30.1 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 46/139 (33%), Gaps = 8/139 (5%) Query: 567 DNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIFIPGGA 626 D A + AY A ++IG G V+P + +ST +F Sbjct: 463 DAAAIELAYKEAKAINPNMIMIGEGWRTFQGDQGKPVKPADQ-DWMKSTDTVGVFSDDIR 521 Query: 627 KAAETLSKN-GRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHESYGV 685 + ++ N G AF G ++ A+ + + ++ Sbjct: 522 NSLKSGFPNEGTP------AFITGGPQSLQGIFKNIKAQPGNFEADSPGDVVQYIAAHDN 575 Query: 686 VTLKKVKPESFTDAVKIAK 704 +TL V +S K+A+ Sbjct: 576 LTLHDVIAKSINKDPKVAE 594 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.124 0.329 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,384,900 Number of Sequences: 36641 Number of extensions: 1091411 Number of successful extensions: 2748 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 2570 Number of HSP's gapped (non-prelim): 75 length of query: 736 length of database: 10,336,785 effective HSP length: 104 effective length of query: 632 effective length of database: 6,526,121 effective search space: 4124508472 effective search space used: 4124508472 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 63 (29.0 bits)