BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BY49 (303 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1YXM-A nrPDB 622 e-179 4FC7-A nrPDB 158 3e-39 4RZH-A nrPDB 152 2e-37 2HQ1-A nrPDB 150 5e-37 2UVD-A nrPDB 143 1e-34 3FTP-A nrPDB 143 1e-34 3RSH-A nrPDB 140 8e-34 1W73-A nrPDB 137 4e-33 3WOH-A nrPDB 135 2e-32 1GEE-A nrPDB 134 3e-32 5ITV-A nrPDB 132 2e-31 3AUT-A nrPDB 131 4e-31 3F9I-A nrPDB 130 8e-31 2PNF-A nrPDB 130 1e-30 1AE1-A nrPDB 128 2e-30 4JRO-A nrPDB 128 2e-30 3OSU-A nrPDB 127 8e-30 5CDY-A nrPDB 122 1e-28 3EMK-A nrPDB 122 3e-28 4KMS-A nrPDB 122 3e-28 5T5Q-A nrPDB 121 4e-28 5OJG-A nrPDB 120 6e-28 4DBZ-A nrPDB 119 2e-27 1Q7C-A nrPDB 119 2e-27 4DMM-A nrPDB 116 1e-26 2CDH-G nrPDB 116 1e-26 3O4R-A nrPDB 115 3e-26 2EW8-A nrPDB 114 6e-26 2C07-A nrPDB 114 7e-26 2AE2-A nrPDB 114 7e-26 4K6F-A nrPDB 112 1e-25 2ZAT-A nrPDB 112 2e-25 4NBT-A nrPDB 111 4e-25 2PH3-A nrPDB 110 5e-25 5VT6-A nrPDB 110 6e-25 4CQM-B nrPDB 110 9e-25 5U9P-A nrPDB 110 1e-24 2HSD-A nrPDB 110 1e-24 6CI9-A nrPDB 108 2e-24 3LYL-A nrPDB 108 4e-24 1K2W-A nrPDB 107 9e-24 3GRP-A nrPDB 106 1e-23 4M8S-A nrPDB 106 1e-23 2CFC-A nrPDB 106 1e-23 4MOW-A nrPDB 105 2e-23 4CR6-A nrPDB 105 2e-23 4Z9Y-A nrPDB 105 3e-23 4BO1-A nrPDB 103 7e-23 3UF0-A nrPDB 103 8e-23 1X1T-A nrPDB 102 2e-22 1H5Q-A nrPDB 102 2e-22 4E6P-A nrPDB 102 2e-22 3WTC-A nrPDB 102 2e-22 4IIN-A nrPDB 101 3e-22 3OEC-A nrPDB 101 4e-22 4RZI-B nrPDB 101 5e-22 5OVL-A nrPDB 99 2e-21 5OVJ-A nrPDB 98 3e-21 3WYE-A nrPDB 98 4e-21 2NM0-A nrPDB 98 5e-21 4NBV-A nrPDB 98 5e-21 3UN1-A nrPDB 98 5e-21 3V2H-A nrPDB 97 6e-21 1GEG-A nrPDB 97 6e-21 3W8F-A nrPDB 97 1e-20 2B4Q-A nrPDB 97 1e-20 4HP8-A nrPDB 96 2e-20 6NRP-A nrPDB 96 2e-20 1AHH-A nrPDB 96 2e-20 1NFF-A nrPDB 94 5e-20 4IS3-A nrPDB 94 5e-20 3OIC-A nrPDB 94 7e-20 3VZS-A nrPDB 94 7e-20 3RWB-A nrPDB 94 9e-20 4AVY-A nrPDB 94 1e-19 3V2G-A nrPDB 93 1e-19 5JS6-A nrPDB 93 2e-19 3EZL-A nrPDB 91 5e-19 5B1Y-A nrPDB 91 6e-19 1UZM-A nrPDB 91 8e-19 4IIV-A nrPDB 89 3e-18 1O5I-A nrPDB 88 4e-18 3GDF-A nrPDB 88 4e-18 3U5T-A nrPDB 88 5e-18 1DOH-A nrPDB 87 8e-18 3U4C-A nrPDB 86 2e-17 5YSS-A nrPDB 86 2e-17 2Q2Q-A nrPDB 86 3e-17 4CQL-A nrPDB 86 3e-17 3PPI-A nrPDB 84 6e-17 1HXH-A nrPDB 84 7e-17 3R3S-A nrPDB 84 1e-16 3A28-C nrPDB 83 1e-16 4TRR-A nrPDB 82 2e-16 2NWQ-A nrPDB 80 7e-16 5EJ2-A nrPDB 80 8e-16 5JY1-A nrPDB 80 9e-16 2FWM-X nrPDB 80 1e-15 2GDZ-A nrPDB 79 2e-15 4EGF-A nrPDB 79 2e-15 3RKU-A nrPDB 79 3e-15 5O3Z-A nrPDB 78 4e-15 3UVE-A nrPDB 76 1e-14 2X9N-A nrPDB 75 2e-14 3T7C-A nrPDB 73 1e-13 3V8B-A nrPDB 72 3e-13 4GKB-A nrPDB 71 5e-13 1P33-A nrPDB 71 6e-13 4DA9-A nrPDB 70 1e-12 1CYD-A nrPDB 70 1e-12 2BGM-A nrPDB 69 3e-12 3D3W-A nrPDB 69 4e-12 3ZV3-A nrPDB 68 4e-12 2BFA-A nrPDB 68 5e-12 2AG5-A nrPDB 68 5e-12 2QHX-A nrPDB 68 6e-12 2YW9-A nrPDB 67 1e-11 1BDB-A nrPDB 64 1e-10 5ILO-A nrPDB 60 2e-09 1E3W-A nrPDB 59 2e-09 5YCX-A nrPDB 59 3e-09 4RGB-A nrPDB 58 5e-09 5IZ4-A nrPDB 58 7e-09 4DRY-A nrPDB 57 1e-08 3OIG-A nrPDB 57 1e-08 2HRB-A nrPDB 56 2e-08 2O23-A nrPDB 54 7e-08 3BHI-A nrPDB 54 8e-08 2NTV-A nrPDB 53 1e-07 1FJH-A nrPDB 53 2e-07 2DKN-A nrPDB 53 2e-07 1ENP-A nrPDB 52 3e-07 2P91-A nrPDB 52 3e-07 2O2S-A nrPDB 52 3e-07 4ALL-A nrPDB 51 5e-07 3OML-A nrPDB 50 1e-06 4M89-A nrPDB 50 2e-06 4Q9N-A nrPDB 49 3e-06 3PXX-A nrPDB 49 3e-06 1N5D-A nrPDB 48 5e-06 5L51-A nrPDB 47 1e-05 5KOI-A nrPDB 46 2e-05 2PTG-A nrPDB 45 4e-05 3GRK-A nrPDB 45 4e-05 6CGE-A nrPDB 45 5e-05 1MG5-A nrPDB 45 5e-05 1A27-A nrPDB 44 6e-05 5I9N-A nrPDB 44 7e-05 4J3F-A nrPDB 44 7e-05 3U9L-A nrPDB 44 9e-05 5TF4-A nrPDB 44 1e-04 5CFZ-A nrPDB 44 1e-04 4JQC-A nrPDB 43 2e-04 4ZJU-A nrPDB 43 2e-04 4OYR-A nrPDB 43 2e-04 3F4B-A nrPDB 43 2e-04 3DWF-A nrPDB 42 2e-04 3UCF-A nrPDB 42 3e-04 3K2E-A nrPDB 42 3e-04 5LCX-A nrPDB 42 4e-04 3KZV-A nrPDB 42 4e-04 4HBG-A nrPDB 40 0.001 5PGZ-A nrPDB 39 0.002 4NK4-A nrPDB 39 0.003 3O26-A nrPDB 39 0.004 2O2Y-A nrPDB 37 0.008 4NR0-A nrPDB 37 0.013 3E9N-A nrPDB 36 0.019 1JPH-A nrPDB 36 0.024 1B15-A nrPDB 36 0.024 4LEC-A nrPDB 35 0.033 1BXK-A nrPDB 32 0.29 5CHL-B nrPDB 31 0.51 1OAA-A nrPDB 31 0.76 2F6M-B nrPDB 30 0.94 2CAZ-B nrPDB 30 1.6 5VEY-A nrPDB 30 1.7 1LU9-A nrPDB 30 1.8 3X0V-A nrPDB 29 2.2 1Z45-A nrPDB 29 2.3 2GN9-A nrPDB 29 2.4 2A9F-A nrPDB 29 2.4 2F8N-K nrPDB 29 2.8 2XQL-A nrPDB 29 2.8 5GT0-C nrPDB 29 3.1 2Q1T-A nrPDB 28 3.7 3C8O-A nrPDB 28 4.6 5Z23-C nrPDB 28 5.0 6DZT-C nrPDB 28 5.8 4B4O-A nrPDB 28 5.8 4NFT-A nrPDB 28 6.0 3LZ1-C nrPDB 28 6.2 1KEU-A nrPDB 28 6.5 4EJ0-A nrPDB 28 6.7 4X23-C nrPDB 28 6.8 4J2Q-A nrPDB 27 7.3 >1YXM-A nrPDB Length = 303 Score = 622 bits (1604), Expect = e-179, Method: Compositional matrix adjust. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD Sbjct: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS Sbjct: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 Query: 121 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN 180 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN Sbjct: 121 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN 180 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS 240 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS Sbjct: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS 240 Query: 241 SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK 300 SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK Sbjct: 241 SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK 300 Query: 301 AKL 303 AKL Sbjct: 301 AKL 303 >4FC7-A nrPDB Length = 277 Score = 158 bits (399), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 90/258 (34%), Positives = 137/258 (53%), Gaps = 6/258 (2%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 R P LL+ +VA +TGG +GIG I + + G + VIASR L R+ +AA +L Sbjct: 17 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG--- 73 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 R +P+ ++R V V L FG+I+ L+N G FL PA +S + V Sbjct: 74 -ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 132 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLA 186 ++ + +GTF + + +Y + ++HGG IVNI G L VH+G+A+A V +T+ LA Sbjct: 133 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 192 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 +EW IR+N +APG I + G Q+ P +R+G E++ V +L Sbjct: 193 VEWGPQNIRVNSLAPGPISGTEGLRRLGGP-QASLSTKVTASPLQRLGNKTEIAHSVLYL 251 Query: 247 LSPAASFITGQSVDVDGG 264 SP AS++TG + DGG Sbjct: 252 ASPLASYVTGAVLVADGG 269 >4RZH-A nrPDB Length = 247 Score = 152 bits (383), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 99/255 (38%), Positives = 139/255 (54%), Gaps = 13/255 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L QVA+VTG + GIGKA L G VV+ + +AAD + A + I Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVV---NYAQSSTAADAVVAEIIA-NGGEAI 59 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +Q N+ N +EV+ L+K+TLD F +I+ LVNN G + + + W AV++ NLTG Sbjct: 60 AVQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGV 119 Query: 136 FYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F KAV +K+ G I+NI V G P + AA+AGV TK++A E A G+ Sbjct: 120 FLCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGV 179 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS-PAASF 253 +N VAPG I + EN + E Q IP R G PEEV+ + FL + PAA++ Sbjct: 180 TVNAVAPGFIATDM-TENLNA------EPILQFIPLARYGQPEEVAGTIRFLATDPAAAY 232 Query: 254 ITGQSVDVDGGRSLY 268 ITGQ+ +VDGG ++ Sbjct: 233 ITGQTFNVDGGMVMF 247 >2HQ1-A nrPDB Length = 247 Score = 150 bits (380), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 93/251 (37%), Positives = 139/251 (55%), Gaps = 11/251 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVI-ASRKLERLKSAADELQANLPPTKQARV 74 L+G+ AIVTG + G+GKAI +L +G+N+V+ S L + A+E +A V Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKA-----AGINV 57 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + + +++N E+V N+VK+ +D FG+I+ LVNN G + +S K W VL TNL Sbjct: 58 VVAKGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKS 117 Query: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 + KAV +K+ G I+NI + G + A++AG+ TKS+A E+A G Sbjct: 118 AYLCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKG 177 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I N VAPG+I + E IP KR G PEEV++VV FL S +++ Sbjct: 178 IYCNAVAPGIIKTDMT----DVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 254 ITGQSVDVDGG 264 ITGQ +++DGG Sbjct: 234 ITGQVINIDGG 244 >2UVD-A nrPDB Length = 246 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 90/255 (35%), Positives = 141/255 (55%), Gaps = 17/255 (6%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN--LPPTKQ- 71 +L+G+VA+VTG + GIG+AI +L + G+NVV+ A +E +AN + K+ Sbjct: 1 MLKGKVALVTGASRGIGRAIAIDLAKQGANVVV--------NYAGNEQKANEVVDEIKKL 52 Query: 72 -ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 + I ++ ++ N E+V N+VK T+D FG+++ LVNN G + + + W V+ T Sbjct: 53 GSDAIAVRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINT 112 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 NL G F KAV M++ G IVNI V G P + AA+AGV LTK+ A E Sbjct: 113 NLKGVFLCTKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKEL 172 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 A I +N +APG I A + ++ + IPA + G +++++ V F S Sbjct: 173 ASRNITVNAIAPGFI----ATDMTDVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASD 228 Query: 250 AASFITGQSVDVDGG 264 + +ITGQ+++VDGG Sbjct: 229 QSKYITGQTLNVDGG 243 >3FTP-A nrPDB Length = 270 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 99/252 (39%), Positives = 137/252 (54%), Gaps = 14/252 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV- 74 L QVAIVTG + GIG+AI EL G+ +VI + E + A+ + A KQA + Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGA-MVIGTATTE---AGAEGIGAAF---KQAGLE 78 Query: 75 -IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 N+ + V+ LV+STL FG +N LVNN G A + W AV++TNL Sbjct: 79 GRGAVLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLK 138 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 F + +AV MK GG IVNI V AG P V+ AA+AGV +T++LA E Sbjct: 139 AVFRLSRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSR 198 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 GI +NCVAPG I + + Q+ + +IP R+G PE+++ V FL SP A Sbjct: 199 GITVNCVAPGFIDTDM-TKGLPQEQQTALK---TQIPLGRLGSPEDIAHAVAFLASPQAG 254 Query: 253 FITGQSVDVDGG 264 +ITG ++ V+GG Sbjct: 255 YITGTTLHVNGG 266 >3RSH-A nrPDB Length = 251 Score = 140 bits (352), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 87/251 (34%), Positives = 136/251 (54%), Gaps = 15/251 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+VA+VTG + GIGKAI + L E G+ V+ + ++ +D L N Sbjct: 10 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKG------- 62 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ N E + ++K+ D FG ++ LVNN G + + + W ++ETNLT Sbjct: 63 -MALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSI 121 Query: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + KAV MK+ G I+N+ +V T A ++ AA+AGV TKS+A E A G Sbjct: 122 FRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYA-AAKAGVIGFTKSMAREVASRG 180 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 + +N VAPG I + + + ++PA R+G P E++S V FL SP A++ Sbjct: 181 VTVNTVAPGFIETDMT----KALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAY 236 Query: 254 ITGQSVDVDGG 264 ITG+++ V+GG Sbjct: 237 ITGETLHVNGG 247 >1W73-A nrPDB Length = 302 Score = 137 bits (346), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 92/264 (34%), Positives = 142/264 (53%), Gaps = 11/264 (4%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 ++ L P QG+VA +TGG TG+GK + L LG+ VIASRK++ LK+ A+++ + Sbjct: 16 KAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQ-- 73 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 +V IQC++R+ + V N V + G N ++NN G F+SP E +S W + Sbjct: 74 --TGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTI 131 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGG----SIVNIIVPTKAGFPLAVHSGAARAGVYNLTK 183 + L GT ++ + +K G SI I T +GF V S +A+AGV ++K Sbjct: 132 TDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGF--VVPSASAKAGVEAMSK 189 Query: 184 SLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVV 243 SLA EW G+R N + PG I ++ A G +F + +IP R+G EE++++ Sbjct: 190 SLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTG-TFEKEMIGRIPCGRLGTVEELANLA 248 Query: 244 CFLLSPAASFITGQSVDVDGGRSL 267 FL S AS+I G + DGG + Sbjct: 249 AFLCSDYASWINGAVIKFDGGEEV 272 >3WOH-A nrPDB Length = 251 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 92/263 (34%), Positives = 136/263 (51%), Gaps = 17/263 (6%) Query: 9 SYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 S PG L G+VA+VTGG+ G+G+A+ L G+ V I + S+A E Q + Sbjct: 2 SMTGPGALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDD---SSAKETQGEIER 58 Query: 69 TK-QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 AR +C++ + E+V VK+ G ++ LVNN G A I + + AV Sbjct: 59 LGGTAR--SYRCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAV 116 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLA 186 + TNL G F KA Y ++++ GSI+NI V G + +A+AG+ LTKS+A Sbjct: 117 MNTNLKGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIA 176 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGS--FQKIPAKRIGVPEEVSSVVC 244 E A +R N VAPG+I + Q + S +P +R G P+EV+ +V Sbjct: 177 KELAERNVRCNAVAPGLIATDMT--------QDLVDDSKRLDPVPMRRFGRPDEVAGLVA 228 Query: 245 FLLSPAASFITGQSVDVDGGRSL 267 FL +S+ITGQ V VDGG ++ Sbjct: 229 FLAGDESSYITGQVVCVDGGMAM 251 >1GEE-A nrPDB Length = 261 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 84/257 (32%), Positives = 142/257 (55%), Gaps = 12/257 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA--R 73 L+G+V ++TG +TG+GK++ + VV+ R E DE + L K+ Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKE------DEANSVLEEIKKVGGE 58 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 I ++ ++ E +V NLV+S + FGK++ ++NN G + + +S W+ V++TNLT Sbjct: 59 AIAVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLT 118 Query: 134 GTFYMCKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 G F + +++ G+++N+ V K +PL VH A++ G+ +T++LALE+A Sbjct: 119 GAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAP 178 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 GIR+N + PG I + E + Q S IP IG PEE+++V +L S A Sbjct: 179 KGIRVNNIGPGAINTPINAEKFADPEQRADVESM--IPMGYIGEPEEIAAVAAWLASSEA 236 Query: 252 SFITGQSVDVDGGRSLY 268 S++TG ++ DGG +LY Sbjct: 237 SYVTGITLFADGGMTLY 253 >5ITV-A nrPDB Length = 255 Score = 132 bits (332), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 86/266 (32%), Positives = 140/266 (52%), Gaps = 32/266 (12%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQ--ANLPPTKQAR 73 L + ++TGGA+GIG A V+ L +NVV+A DE Q A + R Sbjct: 5 LTDKTVLITGGASGIGYAAVQAFLGQQANVVVAD---------IDEAQGEAMVRKENNDR 55 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 + +Q +I +E + V+S + TFG ++ L+NN G + ++P + W+ VL+ NLT Sbjct: 56 LHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLT 115 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 G F M K + G+I+N V +P A++ GV LTKS+A+++A Sbjct: 116 GMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKH 175 Query: 193 GIRINCVAPGVIYS----QTAVENYGSWGQSFFEGSFQKI--------PAKRIGVPEEVS 240 IR+NCV PG+I + ++ +EN EG+ ++I P R+G PEE++ Sbjct: 176 QIRVNCVCPGIIDTPLNEKSFLENN--------EGTLEEIKKEKAKVNPLLRLGKPEEIA 227 Query: 241 SVVCFLLSPAASFITGQSVDVDGGRS 266 +V+ FL S +S++TG ++ DGG + Sbjct: 228 NVMLFLASDLSSYMTGSAITADGGYT 253 >3AUT-A nrPDB Length = 269 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 82/261 (31%), Positives = 145/261 (55%), Gaps = 20/261 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIA--SRKLERLKSAADELQANLPPTKQAR 73 L+ +V ++TGG+TG+G+A+ + + VVI + + E L + + +A + Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAG------GQ 66 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 I +Q ++ EE+V NLV++ + FG ++ ++NN G + P+ +S W+ V++TNLT Sbjct: 67 AIIVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLT 126 Query: 134 GTFYMCKAVYSSWMKEH-GGSIVNI-----IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 G F + +++ G+++N+ ++P +PL VH A++ G+ +T++LAL Sbjct: 127 GAFLGSREAIKYFVENDIKGNVINMSSVHEMIP----WPLFVHYAASKGGMKLMTETLAL 182 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E+A GIR+N + PG + + E + Q S IP IG PEEV++V FL Sbjct: 183 EYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESM--IPMGYIGKPEEVAAVAAFLA 240 Query: 248 SPAASFITGQSVDVDGGRSLY 268 S AS++TG ++ DGG + Y Sbjct: 241 SSQASYVTGITLFADGGMTKY 261 >3F9I-A nrPDB Length = 249 Score = 130 bits (326), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 88/251 (35%), Positives = 135/251 (53%), Gaps = 19/251 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ +++TG ++GIG AI + L +LGS V+I+ E+LKS + L+ N I Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYT-------I 64 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + CN+ N+EE +NL+ T ++ LV N G + A + + + V++ NL Sbjct: 65 EV-CNLANKEECSNLISKT----SNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKAN 119 Query: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + + +++ G I+NI IV AG P + A++AG+ +TKSL+ E A G Sbjct: 120 FILNREAIKKMIQKRYGRIINISSIVGI-AGNPGQANYCASKAGLIGMTKSLSYEVATRG 178 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N VAPG I S + E QKIP G+PE+V+ V FL S AS+ Sbjct: 179 ITVNAVAPGFIKSDMT----DKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASY 234 Query: 254 ITGQSVDVDGG 264 ITGQ++ V+GG Sbjct: 235 ITGQTLHVNGG 245 >2PNF-A nrPDB Length = 248 Score = 130 bits (326), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 93/252 (36%), Positives = 131/252 (51%), Gaps = 13/252 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+V++VTG GIG+AI ++L GS V+I ER K+ A+E+ AN K V Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEI-ANKYGVKAHGV- 62 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ +EE +N + + I+ LVNN G +S W VL+ NLTGT Sbjct: 63 --EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGT 120 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFP---LAVHSGAARAGVYNLTKSLALEWACS 192 F + + +K+ G IVNI + GF V+ +AG+ TKSLA E A Sbjct: 121 FLVTQNSLRKMIKQRWGRIVNI--SSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPR 178 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 + +N VAPG I + Q + E +IP R G PEEV++VV FL S AS Sbjct: 179 NVLVNAVAPGFIETDMTAVLSEEIKQKYKE----QIPLGRFGSPEEVANVVLFLCSELAS 234 Query: 253 FITGQSVDVDGG 264 +ITG+ + V+GG Sbjct: 235 YITGEVIHVNGG 246 >1AE1-A nrPDB Length = 273 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 87/256 (33%), Positives = 134/256 (52%), Gaps = 15/256 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G A+VTGG+ GIG AIV+EL LG+ V SR + L + + K V Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLE-----IWREKGLNVE 73 Query: 76 PIQCNIRNEEEVNNLVKSTLDTF-GKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 C++ + E + L+++ F GK+N LVNN G A+ + K ++ ++ TN Sbjct: 74 GSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEA 133 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF---PLAVHSGAARAGVYNLTKSLALEWAC 191 +++ + Y G++ I + + AGF P A++ + +TKSLA EWA Sbjct: 134 AYHLSQIAYPLLKASQNGNV--IFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAK 191 Query: 192 SGIRINCVAPGVIYS---QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 IR+N VAPGVI + +TA++ + + K P R G P+EVS+++ FL Sbjct: 192 DNIRVNSVAPGVILTPLVETAIKKNPHQKEEI-DNFIVKTPMGRAGKPQEVSALIAFLCF 250 Query: 249 PAASFITGQSVDVDGG 264 PAAS+ITGQ + DGG Sbjct: 251 PAASYITGQIIWADGG 266 >4JRO-A nrPDB Length = 271 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 86/250 (34%), Positives = 127/250 (50%), Gaps = 9/250 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+VA+VTGG+ GIG+ I L + G+N+ AA+E A L V Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFF---NYNGSPEAAEE-TAKLVAEHGVEVE 82 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ N+ E+V+ K ++ FG+++ LVNN G + + W V+ NL GT Sbjct: 83 AMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGT 142 Query: 136 FYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F KAV + MK+ G I+N+ V G + A++AGV LTK+ A E A GI Sbjct: 143 FLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGI 202 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + + E +IP G E++++ V FL S A+ +I Sbjct: 203 NVNAVAPGFITTDMT----DKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYI 258 Query: 255 TGQSVDVDGG 264 TGQ++ VDGG Sbjct: 259 TGQTLSVDGG 268 >3OSU-A nrPDB Length = 246 Score = 127 bits (318), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 82/247 (33%), Positives = 127/247 (51%), Gaps = 13/247 (5%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVI--ASRKLERLKSAADELQANLPPTKQARVIPIQ 78 A+VTG + GIG++I +L E G NV + A K E+ ++ +E++A K IQ Sbjct: 7 ALVTGASRGIGRSIALQLAEEGYNVAVNYAGSK-EKAEAVVEEIKA-----KGVDSFAIQ 60 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 N+ + +EV ++K + FG ++ LVNN G + + + W V++TNL G F Sbjct: 61 ANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNC 120 Query: 139 CKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 + +++ G+I+N+ V G P + A +AGV LTKS A E A GI +N Sbjct: 121 IQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVN 180 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 VAPG I S + E +IP R G ++++ V FL S A +ITGQ Sbjct: 181 AVAPGFIVSDMT----DALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQ 236 Query: 258 SVDVDGG 264 ++ V+GG Sbjct: 237 TIHVNGG 243 >5CDY-A nrPDB Length = 244 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 84/251 (33%), Positives = 138/251 (54%), Gaps = 15/251 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 +G++A+VTG + GIG+AI + L+E G+ VI + E+ A+ + A L + Sbjct: 3 FEGKIALVTGASRGIGRAIAELLVERGA-CVIGTATSEK---GAEAISAYLGENGKG--- 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ + ++ ++ + FG+++ LVNN G + + W +++TNLT Sbjct: 56 -LMLNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSV 114 Query: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + KAV + MK+ G I+ I +V T G V+ AA+AGV +KSLA E A G Sbjct: 115 FRLSKAVMRAMMKKRFGRIITIGSVVGTM-GNAGQVNYAAAKAGVIGFSKSLAREVASRG 173 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N VAPG I +T + + Q G ++PA R+G +E++S V FL S AS+ Sbjct: 174 ITVNVVAPGFI--ETDMTRTLTDDQR--AGILAQVPANRLGDAKEIASAVAFLASDEASY 229 Query: 254 ITGQSVDVDGG 264 I+G+++ V+GG Sbjct: 230 ISGETLHVNGG 240 >3EMK-A nrPDB Length = 246 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 130/257 (50%), Gaps = 21/257 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG G+G+AI + L G+ V + + E+LK A EL R+ Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGE--------RIF 56 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG----GQFLSPAEHISSKGWHAVLETN 131 N+ + E V L + + G ++ LVNN G G F+ +S + W AVL N Sbjct: 57 VFPANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFV----RMSDEDWDAVLTVN 112 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 LT F + + + M+ G I+NI + G P + A++AG+ +KSLA E A Sbjct: 113 LTSVFNLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIA 172 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 + +NC+APG I S G + + IP KR+GV ++++ V +L S Sbjct: 173 SRNVTVNCIAPGFIESAMT----GKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDE 228 Query: 251 ASFITGQSVDVDGGRSL 267 A+++TGQ++ V+GG ++ Sbjct: 229 AAYVTGQTLHVNGGMAM 245 >4KMS-A nrPDB Length = 249 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 86/252 (34%), Positives = 123/252 (48%), Gaps = 17/252 (6%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 ++AIVTGG GIGKA EL G VV AA E++ I + Sbjct: 11 EIAIVTGGTRGIGKATALELKNKGLTVV---ANFFSNYDAAKEMEEKYG-------IKTK 60 Query: 79 C-NIRNEEEVNNLVKSTLDTFGK-INFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 C N+ + EE VK + F K ++ LVNN G +S + W+ V+ NL F Sbjct: 61 CWNVADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCF 120 Query: 137 YMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 M +V + G IVNI + +AG + AA+AG+ TK+LA E A I Sbjct: 121 NMSSSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNIT 180 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +NC+APG I A E G+ + IP KR+G PEE++ V FL+ A FIT Sbjct: 181 VNCIAPGYI----ATEMVGAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFIT 236 Query: 256 GQSVDVDGGRSL 267 G+++ ++GG ++ Sbjct: 237 GETISINGGHNM 248 >5T5Q-A nrPDB Length = 247 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 127/249 (51%), Gaps = 12/249 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + + ++TG GIG+AI + G+N+V+ E L + A L + R+ Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGS------PERIA 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 I+ + + ++ V ++ FG I+FLV + G P +S WH + NL G Sbjct: 61 TIKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGV 120 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 FY+CK + +KE + + G + H GA + + ++T++L+ E A R Sbjct: 121 FYLCKRALPA-LKEDSSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TR 178 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +N V+PG+I + E ++ + + + P KR+G P E++SV+ FL SPAASF+T Sbjct: 179 VNGVSPGIIETPMTSELL----KTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVT 234 Query: 256 GQSVDVDGG 264 G+++ V+GG Sbjct: 235 GETIQVNGG 243 >5OJG-A nrPDB Length = 260 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 89/263 (33%), Positives = 135/263 (51%), Gaps = 29/263 (11%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 +G+VAIVT GIG AI + LL+ G++VVI SR + + A + L+ N TK V Sbjct: 8 FEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLK-NKGLTK---VA 63 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA----EHISSKGWHAVLETN 131 I +I + ++ LV TL FGKIN LVNN G ++PA +S + W + E N Sbjct: 64 GIAGHIASTDDQKKLVDFTLQKFGKINILVNNHG---INPAFGHILEVSDQVWDKLFEVN 120 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 + F M K V+ KE GG+I+ N P G + + LT++LA+ A Sbjct: 121 VKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLA 180 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEG---------SFQKIPAKRIGVPEEVSS 241 IR+N +APGVI ++ + Q ++G Q+I R+GVP++ + Sbjct: 181 KDNIRVNGIAPGVIKTKMS--------QVLWDGGEDAEKELTDIQEIALGRLGVPDDCAG 232 Query: 242 VVCFLLSPAASFITGQSVDVDGG 264 V +L S +S+ITG+ + + GG Sbjct: 233 TVAYLASDDSSYITGEMIIIAGG 255 >4DBZ-A nrPDB Length = 281 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 87/261 (33%), Positives = 136/261 (52%), Gaps = 17/261 (6%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 77 +VA+VTG +GIG I + L + G V + +R E L++ EL +A + + Sbjct: 27 EVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRT----- 81 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 C++R+ E+ LV + ++ +G ++ LVNN G ++ + W V+ETNLTG F Sbjct: 82 -CDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFR 140 Query: 138 MCKAVY-SSWMKEHG-GSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 + K V + M E G G IVNI K G A A++ GV TK+L LE A +GI Sbjct: 141 VTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGI 200 Query: 195 RINCVAPGVIYSQTAV---ENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLL 247 +N V PG + + A E+Y + E +F +I A+ R P EV+ +V +L+ Sbjct: 201 TVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLI 260 Query: 248 SPAASFITGQSVDVDGGRSLY 268 P A+ +T Q+++V GG Y Sbjct: 261 GPGAAAVTAQALNVCGGLGNY 281 >1Q7C-A nrPDB Length = 244 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 80/251 (31%), Positives = 136/251 (54%), Gaps = 15/251 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 +G++A+VTG + GIG+AI + L G+ V+ + ++ +D L AN Sbjct: 3 FEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKG------- 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ + + ++++ FG+++ LVNN G + + + W+ ++ETNL+ Sbjct: 56 -LMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSV 114 Query: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + KAV + MK+ G I+ I +V T A + AA+AG+ +KSLA E A G Sbjct: 115 FRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQA-NFAAAKAGLIGFSKSLAREVASRG 173 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N VAPG I +T + S Q G ++PA R+G +E+++ V FL S A++ Sbjct: 174 ITVNVVAPGFI--ETDMTRALSDDQR--AGILAQVPAGRLGGAQEIANAVAFLASDEAAY 229 Query: 254 ITGQSVDVDGG 264 ITG+++ V+GG Sbjct: 230 ITGETLHVNGG 240 >4DMM-A nrPDB Length = 269 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/251 (32%), Positives = 125/251 (49%), Gaps = 13/251 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L ++A+VTG + GIG+AI EL G+ V + + A + Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYAS----SAGAADEVVAAIAAAGGEAF 81 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ ++ E EV L + ++ +G+++ LVNN G + + W +VL+ NL G Sbjct: 82 AVKADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGV 141 Query: 136 FYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F +A +K+ G I+NI V + G P + AA+AGV LTK++A E A GI Sbjct: 142 FLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGI 201 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS-PAASF 253 +N VAPG I + E E + IP R G EV+ VV FL + PAA++ Sbjct: 202 TVNAVAPGFIATDMTSELAA-------EKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAY 254 Query: 254 ITGQSVDVDGG 264 ITGQ +++DGG Sbjct: 255 ITGQVINIDGG 265 >2CDH-G nrPDB Length = 244 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 125/250 (50%), Gaps = 10/250 (4%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V +VTG + GIGKAI L + G V++ R AA+E+ + + I Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLV---NYARSAKAAEEVSKQIEAYG-GQAITFGG 58 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 ++ E +V ++K+ +D +G I+ +VNN G + + W V++ NLTG F Sbjct: 59 DVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCT 118 Query: 140 KAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 +A MK+ G I+NI V G + AA+AGV +K+ A E A I +N Sbjct: 119 QAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNV 178 Query: 199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL-LSPAASFITGQ 257 V PG I S + G+ + IP R G PE V+ +V FL LSPAAS+ITGQ Sbjct: 179 VCPGFIASDMTAK----LGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQ 234 Query: 258 SVDVDGGRSL 267 + +DGG ++ Sbjct: 235 AFTIDGGIAI 244 >3O4R-A nrPDB Length = 261 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 128/253 (50%), Gaps = 13/253 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L +VA+VT GIG AI + L + G++VV++SRK + + A LQ + V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG-----EGLSVT 67 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLETNLTG 134 C++ E+ LV + + G I+ LV+N F ++ + W L+ N+ Sbjct: 68 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 127 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF---PLAVHSGAARAGVYNLTKSLALEWAC 191 M KAV K GGS+V IV + A F P ++ + LTK+LA+E A Sbjct: 128 PALMTKAVVPEMEKRGGGSVV--IVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 185 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 IR+NC+APG+I +T+ + E + + +R+G PE+ + +V FL S A Sbjct: 186 RNIRVNCLAPGLI--KTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA 243 Query: 252 SFITGQSVDVDGG 264 S+ITG++V V GG Sbjct: 244 SYITGETVVVGGG 256 >2EW8-A nrPDB Length = 249 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 78/251 (31%), Positives = 126/251 (50%), Gaps = 12/251 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+ ++A++TGGA GIG+AI + G+++ IA A E +A + + RV+ Sbjct: 5 LKDKLAVITGGANGIGRAIAERFAVEGADIAIADL------VPAPEAEAAIRNLGR-RVL 57 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++C++ +V K + TFG+ + LVNN G L P + ++ + W E N+ Sbjct: 58 TVKCDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSG 117 Query: 136 FYMCKAVYSSWMKEHG-GSIVNIIVPTK-AGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F M KA + MK +G G I+N+ T H + +A T++LA + G Sbjct: 118 FLMAKA-FVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDG 176 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N +AP ++ + T + S Q IP R+ VP +++ FL S ASF Sbjct: 177 ITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASF 234 Query: 254 ITGQSVDVDGG 264 ITGQ++ VDGG Sbjct: 235 ITGQTLAVDGG 245 >2C07-A nrPDB Length = 285 Score = 114 bits (284), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 83/269 (30%), Positives = 130/269 (48%), Gaps = 16/269 (5%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 + S K +Y G + +VA+VTG GIG+ I K L + S+V+ SR + S D Sbjct: 29 LLSENKKENYYYCG--ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVD 86 Query: 61 ELQA-NLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI 119 E+++ + A ++ +EE++ ++ L ++ LVNN G + + Sbjct: 87 EIKSFGYESSGYA------GDVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRM 140 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAG 177 + W VL TNL FY+ + + + G I+NI IV A +S +++AG Sbjct: 141 KNDEWEDVLRTNLNSLFYITQPISKRMINNRYGRIINISSIVGLTGNVGQANYS-SSKAG 199 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPE 237 V TKSLA E A I +N +APG I S + + IPA R+G PE Sbjct: 200 VIGFTKSLAKELASRNITVNAIAPGFISSDMT----DKISEQIKKNIISNIPAGRMGTPE 255 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDGGRS 266 EV+++ CFL S + +I G+ +DGG S Sbjct: 256 EVANLACFLSSDKSGYINGRVFVIDGGLS 284 >2AE2-A nrPDB Length = 260 Score = 114 bits (284), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 77/252 (30%), Positives = 124/252 (49%), Gaps = 8/252 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G A+VTGG+ GIG IV+EL LG++V SR + L + + +K +V Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWR-----SKGFKVE 61 Query: 76 PIQCNIRNEEEVNNLVKSTLDTF-GKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 C++ + E L+ + + F GK+N LVNN G A+ + + + ++ N Sbjct: 62 ASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEA 121 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEWACSG 193 +++ + G++V I + A P GA + + LT+ LA EWA Sbjct: 122 AYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDN 181 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQ-SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 IR+N V PGVI + Q + +R+G P+E++++V FL PAAS Sbjct: 182 IRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAAS 241 Query: 253 FITGQSVDVDGG 264 ++TGQ + VDGG Sbjct: 242 YVTGQIIYVDGG 253 >4K6F-A nrPDB Length = 255 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 80/262 (30%), Positives = 130/262 (49%), Gaps = 30/262 (11%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVI--------ASRKLERLKSAADELQANLPPTK 70 ++A+VTGG G+G+A+ L + G VV+ A R L + +A E A Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHA------ 65 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 P+ ++ + + ++ + G ++ LVNN G + W AV+ T Sbjct: 66 ----YPV--DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRT 119 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 NL F M K V ++ G IVNI V G + AA+AG++ TKSLALE Sbjct: 120 NLDSVFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEI 179 Query: 190 ACSGIRINCVAPGVIYSQ--TAVENYGSWGQSFFEGS-FQKIPAKRIGVPEEVSSVVCFL 246 A G+ +N V+PG + ++ TA+ Q + +IPA R+G PEEV+++V +L Sbjct: 180 ARKGVTVNTVSPGYLATKMVTAIP------QDILDTKILPQIPAGRLGKPEEVAALVAYL 233 Query: 247 LSPAASFITGQSVDVDGGRSLY 268 S A F+TG ++ ++GG+ ++ Sbjct: 234 CSEEAGFVTGSNIAINGGQHMH 255 >2ZAT-A nrPDB Length = 260 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 128/257 (49%), Gaps = 21/257 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+ +VA+VT GIG AI + L + G++VV++SRK E + LQ + V Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQG-----EGLSVT 66 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-----GQFLSPAEHISSKGWHAVLET 130 C++ E+ LV ++ G ++ LV+N G + E + W +L Sbjct: 67 GTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEV----WDKILHV 122 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAG---FPLAVHSGAARAGVYNLTKSLAL 187 N+ T M KAV K GGS+ +IV + FP ++ + LTK+LA+ Sbjct: 123 NVKATVLMTKAVVPEMEKRGGGSV--LIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAV 180 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E A IR+NC+APG+I +T ++ E + + +R+G PE+ + +V FL Sbjct: 181 ELAPRNIRVNCLAPGLI--KTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLC 238 Query: 248 SPAASFITGQSVDVDGG 264 S AS+ITG++V V GG Sbjct: 239 SEDASYITGETVVVGGG 255 >4NBT-A nrPDB Length = 240 Score = 111 bits (278), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 82/258 (31%), Positives = 128/258 (49%), Gaps = 27/258 (10%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD--ELQANLPPTKQAR 73 L+G+VA++TGGA G+G+AI E G+ V+ A D +L + P Sbjct: 4 LEGKVAVITGGAKGLGQAIALAYAEEGAKVI-----------AGDLGDLTYSHP-----N 47 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 V + N+ + V +S +D +GKI+ LVNN G + ++ W AV++ NL Sbjct: 48 VEGMYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLK 107 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 G F + + V GSI+NI +V A ++ A +AGV LT + A E+A Sbjct: 108 GVFNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYA-ATKAGVIGLTMTWAKEFAL 166 Query: 192 SG--IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 G +R+N +APG I + + Q + R+G PEE++ V FL S Sbjct: 167 KGANVRVNAIAPGYIMTDI----LKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASD 222 Query: 250 AASFITGQSVDVDGGRSL 267 AS++TGQ+++V+GG L Sbjct: 223 DASYVTGQTINVNGGMRL 240 >2PH3-A nrPDB Length = 245 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 85/246 (34%), Positives = 122/246 (49%), Gaps = 10/246 (4%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIA-SRKLERLKSAADELQANLPPTKQARVIPIQC 79 A++TG + GIG+AI L E G + I + E+ + A+E + P V + Sbjct: 4 ALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPL----VAVLGA 59 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 N+ E LV + G ++ LVNN G + + + W AVLE NL+ F Sbjct: 60 NLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTT 119 Query: 140 KAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 + MK G IVNI V G P + A++AG+ T+++A E+A GI +N Sbjct: 120 REAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNA 179 Query: 199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQS 258 VAPG I + E Q E ++IPA R G PEEV+ V FL+S A +ITGQ+ Sbjct: 180 VAPGFIET----EMTERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQT 235 Query: 259 VDVDGG 264 + VDGG Sbjct: 236 LCVDGG 241 >5VT6-A nrPDB Length = 269 Score = 110 bits (276), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 79/259 (30%), Positives = 132/259 (50%), Gaps = 13/259 (5%) Query: 13 PGLLQG-QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 PG +Q +VA VTGG G+G AI + L + G V ++ ER + L + Sbjct: 19 PGSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHS--ERNDHVSTWLMHERDAGRD 76 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETN 131 + + ++ + E + L FGK++ L+NN G + ++ W AV+ T+ Sbjct: 77 FKAYAV--DVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTD 134 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 L F + K + ++ G IVNI + ++ F A ++ +A+AG++ TK+LALE Sbjct: 135 LDAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYA-SAKAGIHGFTKTLALET 193 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGS-FQKIPAKRIGVPEEVSSVVCFLLS 248 A GI +N V+PG Y TA+ + Q E +IP R+G P+EV++++ FL S Sbjct: 194 AKRGITVNTVSPG--YLATAMVE--AVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCS 249 Query: 249 PAASFITGQSVDVDGGRSL 267 A F+TG + ++GG + Sbjct: 250 DDAGFVTGADLAINGGMHM 268 >4CQM-B nrPDB Length = 244 Score = 110 bits (274), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 81/253 (32%), Positives = 126/253 (49%), Gaps = 24/253 (9%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +V V GG+ GIG+A+ + + G + + +R LE K+AA +L + + Sbjct: 10 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH--------LAFS 61 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 C++ E +V N + G++NFLVN G ++ + L TNL G+ Sbjct: 62 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 121 Query: 139 CKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 CKA + +++ GGSIVN+ IV K +V+S A++ G+ +++LA E A IR+ Sbjct: 122 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYS-ASKGGLVGFSRALAKEVARKKIRV 180 Query: 197 NCVAPGVIYSQTAVENYGSWGQSFFEGSFQK-IPAKRIGVPEEVSSVVCFLL-SPAASFI 254 N VAPG +++ + E +K IP R G EV+ V FLL SP +I Sbjct: 181 NVVAPGFVHTDMT--------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YI 229 Query: 255 TGQSVDVDGGRSL 267 TG + VDGG L Sbjct: 230 TGHVLVVDGGLQL 242 >5U9P-A nrPDB Length = 265 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 121/254 (47%), Gaps = 16/254 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A++TG GIG + + L E G+ +VI R E+ + A + A V Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHA-VF 76 Query: 76 PIQCNIRNEEEVNNLVKSTLDTF----GKINFLVNNGGGQFLSPAEHISSKGWHAVLETN 131 + + + V++ +D F G I+ LVNN G Q +P + WHA++ N Sbjct: 77 DVAEHAQ--------VRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVN 128 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 L G F + +AV + G I+NI V ++ P A + V LTK + +WA Sbjct: 129 LDGVFNVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWA 188 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 GI+ N +APG Y +T + +F + ++ PA R G +E+ FL S A Sbjct: 189 RYGIQANGLAPG--YFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAA 246 Query: 251 ASFITGQSVDVDGG 264 + F+ GQ++ VDGG Sbjct: 247 SDFVNGQTLFVDGG 260 >2HSD-A nrPDB Length = 253 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 88/253 (34%), Positives = 123/253 (48%), Gaps = 19/253 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ I+TGGA G+G ++ + G+ VV+A E + A EL AR Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELG------DAARYQ 56 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG---GQFLSPAEHISSKGWHAVLETNL 132 + I EE+ +V + FG ++ LVNN G G FL E S + + V+E NL Sbjct: 57 HLDVTI--EEDWQRVVAYAREEFGSVDGLVNNAGISTGMFL---ETESVERFRKVVEINL 111 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNIIVPTK-AGFPLAVHSGAARAGVYNLTKSLALEWAC 191 TG F K V + GGSIVNI G L GA++ GV L+K A+E Sbjct: 112 TGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGT 171 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 IR+N V PG+ Y+ E G EG++ P R+G P E++ V LLS + Sbjct: 172 DRIRVNSVHPGMTYTPMTAET----GIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTS 227 Query: 252 SFITGQSVDVDGG 264 S++TG + VDGG Sbjct: 228 SYVTGAELAVDGG 240 >6CI9-A nrPDB Length = 259 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 74/254 (29%), Positives = 121/254 (47%), Gaps = 11/254 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ AIVTGG+ GIG+ I + G +VVI R + L D A+L T+ +V Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDL----DRTVADLSGTR-GKVT 61 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ ++ + E+ V T+ G ++ + N G E ++ VL N GT Sbjct: 62 AVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGT 121 Query: 136 FYMCKAVYSSWMKEHGGSIV--NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 Y+ +A + G +V + I G+P H GA++A ++ A+E A Sbjct: 122 VYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKK 181 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I IN V PG I + E GQ + + IPA R+G ++ + F + A++ Sbjct: 182 ITINAVLPGNIMT----EGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAY 237 Query: 254 ITGQSVDVDGGRSL 267 +TGQ++ VDGG+ L Sbjct: 238 VTGQTLVVDGGQVL 251 >3LYL-A nrPDB Length = 247 Score = 108 bits (269), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 82/250 (32%), Positives = 125/250 (50%), Gaps = 10/250 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L +VA+VTG + GIG + L G+ VV + +++A++ + N K + Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATS----QASAEKFE-NSMKEKGFKAR 57 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + NI + E + N I+ LVNN G + +S W +V+ TNL+ Sbjct: 58 GLVLNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSI 117 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F M K MK+ G I++I V AG P + AA+AGV +KSLA E A I Sbjct: 118 FRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNI 177 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + + +SF KIP+ +IG P+++++ V FL S A +I Sbjct: 178 TVNVVAPGFIATDM-TDKLTDEQKSFIA---TKIPSGQIGEPKDIAAAVAFLASEEAKYI 233 Query: 255 TGQSVDVDGG 264 TGQ++ V+GG Sbjct: 234 TGQTLHVNGG 243 >1K2W-A nrPDB Length = 256 Score = 107 bits (266), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 130/258 (50%), Gaps = 17/258 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A++TG A GIG+A + + G+ V IA LE ++ A A + P A Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATA----AEIGPAACA--- 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 I ++ ++ ++ V LD +G I+ LVNN L+P I+ + + + N++GT Sbjct: 56 -IALDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGT 114 Query: 136 FYMCKAVYSSWMK-EHGGSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 +M +AV + + GG I+N+ + G L A +A V +LT+S L G Sbjct: 115 LFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHG 174 Query: 194 IRINCVAPGVIYSQ--TAVENYGSWGQSFFEGSFQK-----IPAKRIGVPEEVSSVVCFL 246 I +N +APGV+ + V+ + ++ G ++ +P R+G E+++ + FL Sbjct: 175 INVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFL 234 Query: 247 LSPAASFITGQSVDVDGG 264 +P A +I Q+ +VDGG Sbjct: 235 ATPEADYIVAQTYNVDGG 252 >3GRP-A nrPDB Length = 266 Score = 106 bits (265), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 77/257 (29%), Positives = 127/257 (49%), Gaps = 21/257 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG GIG+AI + G+ V + + ++LK A +L + V Sbjct: 25 LTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKD--------VF 76 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG----GQFLSPAEHISSKGWHAVLETN 131 N+ + + + L + I+ LVNN G G F+ + + W VL N Sbjct: 77 VFSANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFV----RMQDQDWDDVLAVN 132 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 LT + + + S M+ G I+NI + G P + AA+AG+ +K+LA E A Sbjct: 133 LTAASTLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIA 192 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 I +NC+APG I S A+ + + Q E IP KR+G+ EE++ +L S Sbjct: 193 SRNITVNCIAPGFIKS--AMTDKLNEKQK--EAIMAMIPMKRMGIGEEIAFATVYLASDE 248 Query: 251 ASFITGQSVDVDGGRSL 267 A+++TGQ++ ++GG ++ Sbjct: 249 AAYLTGQTLHINGGMAM 265 >4M8S-A nrPDB Length = 248 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 82/255 (32%), Positives = 123/255 (48%), Gaps = 22/255 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP-TKQARV 74 L G++A+VTG + GIG AI L G+ V+ + +S A + L + RV Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATS----ESGAAAISERLAQWGGEGRV 61 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + N E V NL+ TFGK++ LVNN G + + + W +++ NL Sbjct: 62 L----NSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKS 117 Query: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F KAV MK+ G I+NI V G + AA+AG+ +KS+A E G Sbjct: 118 VFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRG 177 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLSP 249 I +NCVAPG I + ++ E + Q A+ R G ++++ V FL S Sbjct: 178 ITVNCVAPGFIDTDMT--------RALPEETRQTFTAQTALGRFGDAQDIADAVLFLASD 229 Query: 250 AASFITGQSVDVDGG 264 A +ITGQ++ V+GG Sbjct: 230 QAKYITGQTLHVNGG 244 >2CFC-A nrPDB Length = 250 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/249 (30%), Positives = 123/249 (49%), Gaps = 10/249 (4%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VAIVTG ++G G AI L G V E L+ A +V+ ++ Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYAD----KVLRVR 58 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGG--GQFLSPAEHISS-KGWHAVLETNLTGT 135 ++ +E +VN + +T++ FG I+ LVNN G G + H + + + V+ N+ G Sbjct: 59 ADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGI 118 Query: 136 FYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F C+AV + + G IVNI V + FP ++ V LTKS+A+++A SGI Sbjct: 119 FLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGI 178 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R N V PG+I +T + + + +IP K IG +V+ V FL A+++ Sbjct: 179 RCNAVCPGMI--ETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYV 236 Query: 255 TGQSVDVDG 263 G ++ +DG Sbjct: 237 NGAALVMDG 245 >4MOW-A nrPDB Length = 256 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 127/251 (50%), Gaps = 10/251 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+VAIVTG + GIG AI K L + G+ VV+ K+ AD + + + R + Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVV---NYASSKAGADAVVSAITEAG-GRAV 67 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ + +V + ++T+G+++ LVNN G +P E I+ + + +TN+ G Sbjct: 68 AVGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGV 127 Query: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 +A + G SI+NI +V + AV+SG + V +T LALE Sbjct: 128 LLTTQAAVKHLGE--GASIINISSVVTSITPPASAVYSG-TKGAVDAITGVLALELGPRK 184 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+N + PG+I ++ + G G + P R+G P +++SV FL S A + Sbjct: 185 IRVNAINPGMIVTE-GTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARW 243 Query: 254 ITGQSVDVDGG 264 +TG+ + V GG Sbjct: 244 MTGEHLVVSGG 254 >4CR6-A nrPDB Length = 271 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 83/268 (30%), Positives = 129/268 (48%), Gaps = 32/268 (11%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK-- 70 PG L G+ AIVTG A GIG+A V+ L G++VV A +L L T+ Sbjct: 10 PGRLAGKAAIVTGAAGGIGRATVEAYLREGASVV------------AMDLAPRLAATRYE 57 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-----GQFLSPAEHISSKGWH 125 + IPI C++ + ++ + + G ++ LV G G FL +S W Sbjct: 58 EPGAIPIACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFL----DLSDADWD 113 Query: 126 AVLETNLTGTFYMCKA----VYSSWMKEHGGSIVNIIVPTKAGF---PLAVHSGAARAGV 178 ++ N+TGTF C+A + ++ + G S I + + F P A AA+ GV Sbjct: 114 RYVDVNMTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGV 173 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 LT+++A++ A GI +N +APG + N G E ++ R G+PEE Sbjct: 174 AMLTRAMAVDLARHGILVNMIAPGPV--DVTGNNTGYSEPRLAEQVLDEVALGRPGLPEE 231 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRS 266 V++ FL +SFITG ++ +DGG S Sbjct: 232 VATAAVFLAEDGSSFITGSTITIDGGLS 259 >4Z9Y-A nrPDB Length = 253 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 72/257 (28%), Positives = 129/257 (50%), Gaps = 23/257 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLE-----LGSNVVIASRKLERLKSAADELQANLPPTK 70 LQG+VA++TG TG+G+ + L + +G N+V +E++ + Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALG----------- 56 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 R + + ++ N LV+ + FG ++ LVNN G A S K W V+ Sbjct: 57 -RRFLSLTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNL 115 Query: 131 NLTGTFYMCKAVYSSWMKE-HGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 N+ F+M + V ++K+ GG I+NI ++ + G + ++ A+++ V +T+ +A Sbjct: 116 NIKSVFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYT-ASKSAVMGVTRLMAN 174 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 EWA GI +N +APG + + + +S + +IPA R G+P+++ FL Sbjct: 175 EWAKHGINVNAIAPGYMATNNTQQLRADEERS--KEILDRIPAGRWGLPQDLMGPSVFLA 232 Query: 248 SPAASFITGQSVDVDGG 264 S A+ +I G ++ VDGG Sbjct: 233 SSASDYINGYTIAVDGG 249 >4BO1-A nrPDB Length = 269 Score = 103 bits (258), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 80/250 (32%), Positives = 125/250 (50%), Gaps = 10/250 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+VA+VTG + GIG+AI EL LG+ V+ + + A+ L+AN + A ++ Sbjct: 25 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKAN--GVEGAGLV 82 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ ++E V ++ G+ +VNN G + + W V+ TNL Sbjct: 83 ---LDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSL 139 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 + + KAV K G I+NI V G + AA+AG+ T++LA E I Sbjct: 140 YRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAI 199 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + E ++ E +IP R+G EE++ VV FL S A+++ Sbjct: 200 TVNAVAPGFIDTDMTRE----LPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYV 255 Query: 255 TGQSVDVDGG 264 TG +V V+GG Sbjct: 256 TGATVPVNGG 265 >3UF0-A nrPDB Length = 273 Score = 103 bits (257), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 80/260 (30%), Positives = 135/260 (51%), Gaps = 14/260 (5%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 +S P L G+ A+VTG +GIG+AI G++V +A + + +K ADE+ A+ Sbjct: 21 QSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHV-LAWGRTDGVKEVADEI-ADGG 78 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 + +A + ++ + E N+ + T +++ LVNN G +PAE +S W V Sbjct: 79 GSAEA----VVADLADLEGAANVAEELAATR-RVDVLVNNAGIIARAPAEEVSLGRWREV 133 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSL 185 L NL + + ++ ++ + G IV I ++ + G +A ++ A++ V LT++L Sbjct: 134 LTVNLDAAWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYA-ASKHAVVGLTRAL 192 Query: 186 ALEWACSGIRINCVAPG-VIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 A EWA G+ +N +APG V+ + TA + +IPA R PE++ Sbjct: 193 ASEWAGRGVGVNALAPGYVVTANTAALRADDERAAEIT---ARIPAGRWATPEDMVGPAV 249 Query: 245 FLLSPAASFITGQSVDVDGG 264 FL S AAS++ GQ + VDGG Sbjct: 250 FLASDAASYVHGQVLAVDGG 269 >1X1T-A nrPDB Length = 260 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 82/263 (31%), Positives = 125/263 (47%), Gaps = 20/263 (7%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD--ELQANLPPTKQA 72 +L+G+VA+VTG +GIG I L G+++V L AA+ +++A L Sbjct: 1 MLKGKVAVVTGSTSGIGLGIATALAAQGADIV-----LNGFGDAAEIEKVRAGLAAQHGV 55 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 +V+ ++ E V LV + + G+I+ LVNN G Q + E ++ W A+L NL Sbjct: 56 KVLYDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNL 115 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSG---AARAGVYNLTKSLALEW 189 + F+ A K+ G I+NI + G + + AA+ GV TK ALE Sbjct: 116 SAVFHGTAAALPHMKKQGFGRIINI--ASAHGLVASANKSAYVAAKHGVVGFTKVTALET 173 Query: 190 ACSGIRINCVAPGVI--------YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSS 241 A GI N + PG + S A +N + E +K P+ + PE++ Sbjct: 174 AGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGG 233 Query: 242 VVCFLLSPAASFITGQSVDVDGG 264 FL S AA+ ITG +V VDGG Sbjct: 234 TAVFLASDAAAQITGTTVSVDGG 256 >1H5Q-A nrPDB Length = 265 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 83/275 (30%), Positives = 132/275 (48%), Gaps = 26/275 (9%) Query: 9 SYLAPGL---LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 S++APG + IVTGG GIG A + + G+NV + R SAAD ++ Sbjct: 2 SHMAPGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYR------SAADAVEVT 55 Query: 66 LPPTKQ--ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG 123 K+ + QC++ N + V ++ G I+ L+ N G + PA ++ + Sbjct: 56 EKVGKEFGVKTKAYQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHED 115 Query: 124 WHAVLETNLTGTFYMCKAVYSSWM-KEHGGSIV-------NIIVPTKAGFPLA-VHSGAA 174 + V + N+ G F C+AV W+ K+ GSIV II + L V ++ Sbjct: 116 FAFVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSS 175 Query: 175 RAGVYNLTKSLALEWACSGIRINCVAPGVIYS-QTAVENYGSWGQSFFEGSFQKIPAKRI 233 +A NL K LA EWA +GIR+N ++PG + + QTA + + IP R Sbjct: 176 KAACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTA-----HMDKKIRDHQASNIPLNRF 230 Query: 234 GVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLY 268 PEE++ LLS A+++TG +DGG+ ++ Sbjct: 231 AQPEEMTGQAILLLSDHATYMTGGEYFIDGGQLIW 265 >4E6P-A nrPDB Length = 259 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 70/260 (26%), Positives = 127/260 (48%), Gaps = 21/260 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ A++TG A GIG+A + + G+ V IA +ER + AA A + P A Sbjct: 6 LEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAA----AEIGPAAYA--- 58 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +Q ++ ++ ++ + +T++ G ++ LVNN L+P I+ + + + N+ GT Sbjct: 59 -VQMDVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGT 117 Query: 136 FYMCKAVYSSWMKE-HGGSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 + +A + + GG I+N+ + G L A +A V +LT+S L+ Sbjct: 118 LFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHR 177 Query: 194 IRINCVAPGVIYSQ---------TAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 I +N +APGV+ + EN + G + +P R+G E+++ + Sbjct: 178 INVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVG--EAVPFGRMGTAEDLTGMAI 235 Query: 245 FLLSPAASFITGQSVDVDGG 264 FL S + +I Q+ +VDGG Sbjct: 236 FLASAESDYIVSQTYNVDGG 255 >3WTC-A nrPDB Length = 262 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 124/259 (47%), Gaps = 16/259 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G++A VTG A GIGKAI L + G++V++ K + L A E++A R + Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEA-----LGRRAV 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + +I N ++ + + T G ++ +VNN G + P I + N+ G Sbjct: 61 ALTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGV 120 Query: 136 FYMCKAVYSSWMKEHG--GSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 + +A ++ KE G G I+N + G+PL A + V LT+S A E A S Sbjct: 121 LWGMQAA-ATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASS 179 Query: 193 GIRINCVAPGVI-------YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 GI +N PG++ + E G+ + ++ + I R+ ++V+ V + Sbjct: 180 GITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAY 239 Query: 246 LLSPAASFITGQSVDVDGG 264 L S A ++TGQSV +DGG Sbjct: 240 LSSSDADYMTGQSVLIDGG 258 >4IIN-A nrPDB Length = 271 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 125/259 (48%), Gaps = 13/259 (5%) Query: 10 YLAPGLLQ--GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 Y +Q G+ ++TG + GIG I K L +G V I R + AD L+ L Sbjct: 19 YFQSNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEV---ADALKNELE 75 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 K + I+ + +E + +++ + + G +++LVNN G A + ++ +H V Sbjct: 76 E-KGYKAAVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHV 134 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSL 185 ++ NLT F C+ K GS+VN+ I+ + +S A++ G+ ++KS Sbjct: 135 IDNNLTSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYS-ASKGGMIAMSKSF 193 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 A E A IR N V PG I + + + IP R+G +EV+ V F Sbjct: 194 AYEGALRNIRFNSVTPGFIETDMNANLKDELKADY----VKNIPLNRLGSAKEVAEAVAF 249 Query: 246 LLSPAASFITGQSVDVDGG 264 LLS +S+ITG+++ V+GG Sbjct: 250 LLSDHSSYITGETLKVNGG 268 >3OEC-A nrPDB Length = 317 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 82/275 (29%), Positives = 132/275 (48%), Gaps = 30/275 (10%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVI-----ASRKLERLKSAADELQ--ANLPP 68 LQG+VA +TG A G G+ L + G+++V L+ + + +EL+ L Sbjct: 44 LQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVE 103 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 + R+I Q ++R+ + +V L FG I+ LV+N G ++ + W +L Sbjct: 104 EQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDIL 163 Query: 129 ETNLTGTFYMCKAVYSSWMKE-HGGSIVNIIVPTKAGF---PLAVHSGAARAGVYNLTKS 184 +TNL G ++ C+AV S ++ GGS+ I V + G P H A++ GV L S Sbjct: 164 QTNLIGAWHACRAVLPSMIERGQGGSV--IFVSSTVGLRGAPGQSHYAASKHGVQGLMLS 221 Query: 185 LALEWACSGIRINCVAPGVIYSQTA------------VEN--YGSWGQSFFEGSFQKIPA 230 LA E IR+N V PG + ++ A +EN + F + + IP Sbjct: 222 LANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIPW 281 Query: 231 KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265 PE+VS+ V +L S A +I G ++ VDGG+ Sbjct: 282 VE---PEDVSNAVAWLASDEARYIHGAAIPVDGGQ 313 >4RZI-B nrPDB Length = 240 Score = 101 bits (251), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 85/256 (33%), Positives = 124/256 (48%), Gaps = 33/256 (12%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+ +V +VTGG GIG AIVK L E+G+ V A +L + T+ V+ Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKV------------AFTDLATDGGNTEALGVV 53 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG---GQF---LSPAEHISSKGWHAVLE 129 N+ + E + D G + +V N G F L+PA+ W AVL Sbjct: 54 ---ANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPAD------WDAVLN 104 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 NL G Y K + GSIV I + + G + A +AGV + KSLA E Sbjct: 105 VNLKGVAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLARE 164 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 A G+R N VAPG I ++ + + + E ++IP +R G PEE++ V FLLS Sbjct: 165 GARYGVRANAVAPGFIDTEMTL----AIREDIREKITKEIPFRRFGKPEEIAWAVAFLLS 220 Query: 249 P-AASFITGQSVDVDG 263 P A+S++TG+ + V+G Sbjct: 221 PVASSYVTGEVLRVNG 236 >5OVL-A nrPDB Length = 300 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 74/247 (29%), Positives = 114/247 (46%), Gaps = 21/247 (8%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +VTGG GIG AI + L G V + R A D+L +QC++ Sbjct: 72 LVTGGNRGIGLAIARRLAADGHKVAVTHRG----SGAPDDL------------FGVQCDV 115 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 + V+ K + G + LV N G + ++ + + V+ TNLTG F + Sbjct: 116 TDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQR 175 Query: 142 VYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVA 200 + ++ G I+ I V G + AA+AG+ + +S++ E A +G+ N VA Sbjct: 176 ASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVA 235 Query: 201 PGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVD 260 PG I + E + + G+ IPAKR+G EEV+ V FL S AS+I G + Sbjct: 236 PGYIDT----EMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 291 Query: 261 VDGGRSL 267 VDGG + Sbjct: 292 VDGGMGM 298 >5OVJ-A nrPDB Length = 256 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 74/247 (29%), Positives = 114/247 (46%), Gaps = 21/247 (8%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +VTGG GIG AI + L G V + R A D+L +QC++ Sbjct: 28 LVTGGNRGIGLAIARRLAADGHKVAVTHRG----SGAPDDL------------FGVQCDV 71 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 + V+ K + G + LV N G + ++ + + V+ TNLTG F + Sbjct: 72 TDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQR 131 Query: 142 VYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVA 200 + ++ G I+ I V G + AA+AG+ + +S++ E A +G+ N VA Sbjct: 132 ASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVA 191 Query: 201 PGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVD 260 PG I + E + + G+ IPAKR+G EEV+ V FL S AS+I G + Sbjct: 192 PGYIDT----EMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 247 Query: 261 VDGGRSL 267 VDGG + Sbjct: 248 VDGGMGM 254 >3WYE-A nrPDB Length = 256 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 78/257 (30%), Positives = 125/257 (48%), Gaps = 18/257 (7%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 77 +VA+VTG GIGKAI L++ G V IA K+ A E+ QA + + Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAG------GHAVAV 56 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 + ++ + ++V V+ T G + +VNN G + P ++ + + N+ F+ Sbjct: 57 KVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFF 116 Query: 138 MCKAVYSSWMKE-HGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 +A ++ KE HGG I+N GFP+ + V LT++ A + A GI Sbjct: 117 GIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGIT 176 Query: 196 INCVAPGVI----YSQTAVE----NYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 +N PG++ + Q E N G++F E S I R VPE+V+ +V FL Sbjct: 177 VNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYS-SSIALGRPSVPEDVAGLVSFLA 235 Query: 248 SPAASFITGQSVDVDGG 264 SP + ++TGQS+ +DGG Sbjct: 236 SPDSDYMTGQSLLIDGG 252 >2NM0-A nrPDB Length = 253 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 77/255 (30%), Positives = 115/255 (45%), Gaps = 21/255 (8%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 L P + +VTGG GIG AI + + G V I R E PP Sbjct: 14 LVPRSHMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGE-------------PPEG 60 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 + ++C+I + E+V K +T G + L+ N G +S + + +V+ET Sbjct: 61 ---FLAVKCDITDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVET 117 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 NLTGTF + K + ++ G +V I V G + A++AG+ +SLA E Sbjct: 118 NLTGTFRVVKRANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLAREL 177 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 I N VAPG + T + + Q ++P R PEE+++ V FL S Sbjct: 178 GSRNITFNVVAPG--FVDTDMTKVLTDEQR--ANIVSQVPLGRYARPEEIAATVRFLASD 233 Query: 250 AASFITGQSVDVDGG 264 AS+ITG + VDGG Sbjct: 234 DASYITGAVIPVDGG 248 >4NBV-A nrPDB Length = 246 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 78/255 (30%), Positives = 125/255 (49%), Gaps = 14/255 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+VAI+TG A GIG A + E G+ VV+ + R++ AA L A RV Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRV- 61 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ +EV+ +V + L +++ LVNN G + ++ + AV++ NL G Sbjct: 62 ----DVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGV 117 Query: 136 FYMCKAVYSSWMKEHG-GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 F +AV + M E G G I+N +V F + A++ GV TK+ A E Sbjct: 118 FNCAQAV-AGLMTEQGKGVILNASSVVGLYGNFG-QTNYAASKFGVIGFTKTWARELGPK 175 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 G+R+N V PG + + E + +G +R+ P E++S+ FL S AS Sbjct: 176 GVRVNAVCPGFVNT----EILQTVPDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDAS 231 Query: 253 FITGQSVDVDGGRSL 267 ++ G +++ GG SL Sbjct: 232 YVNGVAIEASGGMSL 246 >3UN1-A nrPDB Length = 260 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 70/254 (27%), Positives = 124/254 (48%), Gaps = 28/254 (11%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 Q +V ++TG + GIG +V+ + VV SR ++ P+ + Sbjct: 27 QQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIK--------------PSADPDIHT 72 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 + +I E + +V+ ++ FG+I+ LVNN G P ++ + + L N+ G F Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFF 132 Query: 137 YMCKAVYSSWMKEHGGSIVNI----IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 ++ + + +K+ G IV+I + G P A+ S + G+ +T+SLA+E++ S Sbjct: 133 HITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALAS-LTKGGLNAVTRSLAMEFSRS 191 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 G+R+N V+PGVI + + + S G P R+G +V V +L A Sbjct: 192 GVRVNAVSPGVIKTPM----HPAETHSTLAGLH---PVGRMGEIRDVVDAVLYL--EHAG 242 Query: 253 FITGQSVDVDGGRS 266 FITG+ + VDGG++ Sbjct: 243 FITGEILHVDGGQN 256 >3V2H-A nrPDB Length = 281 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 121/261 (46%), Gaps = 18/261 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKL-ERLKSAADELQANLPPTKQARV 74 + + A++TG +GIG AI + L + G+N+V+ + +++ DE+ V Sbjct: 23 MMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAG----LSSGTV 78 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++ E+ +++ D FG + LVNN G QF+ E + W ++ NL+ Sbjct: 79 LHHPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSS 138 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF---PLAVHSGAARAGVYNLTKSLALEWAC 191 +F+ + K+ G I+NI + G P AA+ G+ LTK++ALE A Sbjct: 139 SFHTIRGAIPPMKKKGWGRIINI--ASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAE 196 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWG--------QSFFEGSFQKIPAKRIGVPEEVSSVV 243 SG+ +N + PG + + + Q E + P K+ E+V+S+ Sbjct: 197 SGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLA 256 Query: 244 CFLLSPAASFITGQSVDVDGG 264 +L A+ ITG V +DGG Sbjct: 257 LYLAGDDAAQITGTHVSMDGG 277 >1GEG-A nrPDB Length = 256 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 78/262 (29%), Positives = 132/262 (50%), Gaps = 28/262 (10%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA+VTG GIGKAI L++ G V IA K+ A E+ + ++ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEIN-----QAGGHAVAVK 57 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ + ++V V+ T G + +VNN G +P E I+ + V N+ G + Sbjct: 58 VDVSDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWG 117 Query: 139 CKAVYSSWMKE-HGGSIVNIIVPTKAGF----PLAVHSGAARAGVYNLTKSLALEWACSG 193 +A ++ KE HGG I+N ++AG LAV+S +++ V LT++ A + A G Sbjct: 118 IQAAVEAFKKEGHGGKIINAC--SQAGHVGNPELAVYS-SSKFAVRGLTQTAARDLAPLG 174 Query: 194 IRINCVAPGVI-----------YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSV 242 I +N PG++ S+ A + G +G + F ++I R+ PE+V++ Sbjct: 175 ITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLG-YGTAEFA---KRITLGRLSEPEDVAAC 230 Query: 243 VCFLLSPAASFITGQSVDVDGG 264 V +L SP + ++TGQS+ +DGG Sbjct: 231 VSYLASPDSDYMTGQSLLIDGG 252 >3W8F-A nrPDB Length = 260 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 74/265 (27%), Positives = 123/265 (46%), Gaps = 24/265 (9%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVI----ASRKLERLKSAADELQANLPPTK 70 +L+G+ A+VTG +GIG A+ EL + G++VVI +ER +S L Sbjct: 1 MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERS-------TLESKF 53 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 + + ++ + + + + + G ++ LVNN G Q +P E W+A++ Sbjct: 54 GVKAYYLNADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIAL 113 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSG---AARAGVYNLTKSLAL 187 NL+ F+ A K+ G I+NI + G +V+ AA+ GV LTK AL Sbjct: 114 NLSAVFHGTAAALPIMQKQGWGRIINI--ASAHGLVASVNKSAYVAAKHGVVGLTKVTAL 171 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQ--------SFFEGSFQKIPAKRIGVPEEV 239 E A GI N + PG + + + + Q + E +K P+ + PE++ Sbjct: 172 ENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQL 231 Query: 240 SSVVCFLLSPAASFITGQSVDVDGG 264 FL S AA +TG ++ +DGG Sbjct: 232 GGAAVFLSSAAADQMTGTTLSLDGG 256 >2B4Q-A nrPDB Length = 276 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 122/258 (47%), Gaps = 14/258 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G++A+VTGG+ GIG+ I + LLE G+ V I +R E A L A + I Sbjct: 27 LAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSA----YGDCQAI 82 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 P ++ +E L ++ + +++ LVNN G + + E GW V++ N+T Sbjct: 83 P--ADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSV 140 Query: 136 F----YMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 F + + S E+ ++NI + A A G ++A ++ L++ LA E Sbjct: 141 FSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKEL 200 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 I +N +APG S+ + + + E IP R G PEE++++ L Sbjct: 201 VGEHINVNVIAPGRFPSR--MTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGT 258 Query: 250 AASFITGQSVDVDGGRSL 267 A +++TG + +DGG L Sbjct: 259 AGAYMTGNVIPIDGGFHL 276 >4HP8-A nrPDB Length = 247 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 122/258 (47%), Gaps = 24/258 (9%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE-LQANLPPTKQ 71 P L+G+ A+VTG TG+G+AI L G+ VV A+R+ A DE L Sbjct: 4 PFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARR------APDETLDIIAKDGGN 57 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETN 131 A + I + L T + LVNN G + + S W V++ N Sbjct: 58 ASALLIDF-------ADPLAAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVN 110 Query: 132 LTGTFYMCKAVYSSWM-KEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 L F+ +A + K G +VNI ++ + G + ++ AA+ GV LTK LA E Sbjct: 111 LKALFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYT-AAKHGVAGLTKLLANE 169 Query: 189 WACSGIRINCVAPGVIYSQT--AVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 WA GI +N +APG I + A+ + ++ E +IPA R G E+++ FL Sbjct: 170 WAAKGINVNAIAPGYIETNNTEALRADAARNKAILE----RIPAGRWGHSEDIAGAAVFL 225 Query: 247 LSPAASFITGQSVDVDGG 264 S AA ++ G ++VDGG Sbjct: 226 SSAAADYVHGAILNVDGG 243 >6NRP-A nrPDB Length = 263 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 75/245 (30%), Positives = 122/245 (49%), Gaps = 13/245 (5%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +VTG + GIGKAI +L + G +V + +R R A +Q + + + N Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARS--RQAEAEQVVQEIQALGQNSHYLMFDVNE 85 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 R + V +++ ++ G +V N G ++ + W V+ T+L G + + K Sbjct: 86 R--QTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKP 143 Query: 142 VYSSWMK-EHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCV 199 + + GG IV + V G V+ AA+AG+ TK+LALE A I +NCV Sbjct: 144 LIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCV 203 Query: 200 APGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSV 259 APG+I ++ + E + + IP +R+G +EV+SVV FL S AS++T Q + Sbjct: 204 APGLIETEMVTDEVK-------EHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVI 256 Query: 260 DVDGG 264 V+GG Sbjct: 257 SVNGG 261 >1AHH-A nrPDB Length = 255 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 123/250 (49%), Gaps = 10/250 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ AI+TG GIGK I G++VV++ + DE+Q + Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-----QLGGQAF 63 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +C+I +E+E++ L + GK++ LVNN GG P + + + E N+ Sbjct: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSF 122 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAV-HSGAARAGVYNLTKSLALEWACSGI 194 F++ + V K GG I+ I + + +++A +L +++A + I Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R+N +APG I + A+++ + + Q P +R+G P+++++ FL SPAAS++ Sbjct: 183 RVNGIAPGAILTD-ALKSVIT--PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 Query: 255 TGQSVDVDGG 264 +GQ + V GG Sbjct: 240 SGQILTVSGG 249 >1NFF-A nrPDB Length = 260 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 81/253 (32%), Positives = 120/253 (47%), Gaps = 20/253 (7%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 G L G+VA+V+GGA G+G + V+ ++ G+ VV DE + Sbjct: 3 GRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGD--------ILDEEGKAMAAELADA 54 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 + ++ + V + + FG ++ LVNN G + E + W +L+ NLT Sbjct: 55 ARYVHLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLT 114 Query: 134 GTFYMCKAVYSSWMKEHG-GSIVNIIVPTKAGFPLAVHS-GAARAGVYNLTKSLALEWAC 191 G F +AV MKE G GSI+NI +A H A + V LTKS ALE Sbjct: 115 GVFLGIRAVVKP-MKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGP 173 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 SGIR+N + PG++ +T + ++ E FQ R P EVS++V +L S + Sbjct: 174 SGIRVNSIHPGLV--KTPMTDW------VPEDIFQT-ALGRAAEPVEVSNLVVYLASDES 224 Query: 252 SFITGQSVDVDGG 264 S+ TG VDGG Sbjct: 225 SYSTGAEFVVDGG 237 >4IS3-A nrPDB Length = 268 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 117/256 (45%), Gaps = 20/256 (7%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+Q +V I+TGG GIG A K ++ G+ V I E + +A +L+ P + V Sbjct: 22 LVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYP---EEEV 78 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++ + + V V +G+++ ++NN G + +S + + +++ N+TG Sbjct: 79 LGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTG 138 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTK-------AGFPLAVHSGAARAGVYNLTKSLAL 187 F Y G I+N T G+P A++A V LT L Sbjct: 139 VFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYP------ASKASVIGLTHGLGR 192 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E IR+ VAPGV+ + N EG + +P KR+ PEE+++V FL Sbjct: 193 EIIRKNIRVVGVAPGVVNTDMTNGN----PPEIMEGYLKALPMKRMLEPEEIANVYLFLA 248 Query: 248 SPAASFITGQSVDVDG 263 S AS IT +V VDG Sbjct: 249 SDLASGITATTVSVDG 264 >3OIC-A nrPDB Length = 258 Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 122/255 (47%), Gaps = 13/255 (5%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 Q + A+VTG + G+GKA L E G N+VI R K AA E + +V+ Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVI---NYARSKKAALETAEEIEKLG-VKVLV 58 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 ++ N+ ++ + + +TFG+++ VNN L P + W + N Sbjct: 59 VKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALL 118 Query: 137 YMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS----GAARAGVYNLTKSLALEWACS 192 + + K GG IV+I + G + + G ++A + LT+ LA+E + Sbjct: 119 FCAQEAAKLMEKNGGGHIVSI---SSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPK 175 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 I +N V+ G I + A++++ + + E + Q PA R+ +++ V FL+S A Sbjct: 176 QIIVNAVSGGAIDTD-ALKHFPNR-EDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKAD 233 Query: 253 FITGQSVDVDGGRSL 267 I GQ++ VDGGRSL Sbjct: 234 MIRGQTIIVDGGRSL 248 >3VZS-A nrPDB Length = 257 Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 113/248 (45%), Gaps = 11/248 (4%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 ++A VTGG GIG AI + L + G VV + E Q L I + Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALG----FDFIASE 70 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 N+ + + G+++ L+NN G ++ W AV++TNLT F + Sbjct: 71 GNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNV 130 Query: 139 CKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 K V G IVNI + K F +S A+AG++ T +LA E A G+ + Sbjct: 131 TKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYS-TAKAGLHGFTMALAQEVATKGVTV 189 Query: 197 NCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITG 256 N V+PG I A + + Q + IP KR+G+PEE++S+ +L S + F TG Sbjct: 190 NTVSPGYI----ATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTG 245 Query: 257 QSVDVDGG 264 ++GG Sbjct: 246 ADFSLNGG 253 >3RWB-A nrPDB Length = 247 Score = 93.6 bits (231), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 84/252 (33%), Positives = 121/252 (48%), Gaps = 15/252 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG A GIGKAI L G+ V+++ E K+AA + K+AR I Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIG------KKARAI 57 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +I + V L G I+ LVNN + + W +++ NLTGT Sbjct: 58 A--ADISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGT 115 Query: 136 FYMCKAVYSSWMKEHG--GSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 F + +A + M+ G G +++I T AG P AA+ GV T++LA E Sbjct: 116 FIVTRA-GTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKY 174 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 I N V PG+I S + + F E Q + K G PE ++ VV FL S A Sbjct: 175 NITANAVTPGLIESDGVKASPHNEAFGFVE-MLQAMKGK--GQPEHIADVVSFLASDDAR 231 Query: 253 FITGQSVDVDGG 264 +ITGQ+++VD G Sbjct: 232 WITGQTLNVDAG 243 >4AVY-A nrPDB Length = 242 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 119/252 (47%), Gaps = 29/252 (11%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 GQ +VTGG++GIG AI + ELG+ VV L AD + A P R+ Sbjct: 11 GQQVLVTGGSSGIGAAIAMQFAELGAEVVA-------LGLDADGVHAPRHP----RIRRE 59 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 + +I + + + L + +++ LVNN G E + VL NL+ Sbjct: 60 ELDITDSQRLQRL----FEALPRLDVLVNNAG--ISRDREEYDLATFERVLRLNLSAAM- 112 Query: 138 MCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 + + + + GGSI+NI + T +S A++ + LT+SLA E+A IR Sbjct: 113 LASQLARPLLAQRGGSILNIASMYSTFGSADRPAYS-ASKGAIVQLTRSLACEYAAERIR 171 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGS---FQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 +N +APG I + G+ ++ E + Q+ P R G EV+S FL P AS Sbjct: 172 VNAIAPGWIDTP-----LGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGAS 226 Query: 253 FITGQSVDVDGG 264 F+TG + VDGG Sbjct: 227 FVTGAVLAVDGG 238 >3V2G-A nrPDB Length = 271 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 72/257 (28%), Positives = 120/257 (46%), Gaps = 25/257 (9%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA--R 73 L G+ A VTGG+ GIG AI K L G+ V + +AA+ QA + +QA R Sbjct: 29 LAGKTAFVTGGSRGIGAAIAKRLALEGAAVALT------YVNAAERAQAVVSEIEQAGGR 82 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 + I+ + R+ E + ++ T++ G ++ LVN+ G +P E + + V+ N Sbjct: 83 AVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFR 142 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI------IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 F ++ +S GG I+ I +VP +P A++A + LTK LA Sbjct: 143 APFVAIRS--ASRHLGDGGRIITIGSNLAELVP----WPGISLYSASKAALAGLTKGLAR 196 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 + GI +N V PG + + E ++I G P++++ +V +L Sbjct: 197 DLGPRGITVNIVHPGSTDT-----DMNPADGDHAEAQRERIATGSYGEPQDIAGLVAWLA 251 Query: 248 SPAASFITGQSVDVDGG 264 P F+TG S+ +DGG Sbjct: 252 GPQGKFVTGASLTIDGG 268 >5JS6-A nrPDB Length = 274 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 120/239 (50%), Gaps = 19/239 (7%) Query: 35 VKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKST 94 V+ + G+ VVI + +S L+ LP + I C++ E++V LV T Sbjct: 28 VRAFVNSGARVVICDKD----ESGGRALEQELP-----GAVFILCDVTQEDDVKTLVSET 78 Query: 95 LDTFGKINFLVNNGGGQFLSP--AEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGG 152 + FG+++ +VNN G P E S++G+ +LE NL GT+ + K ++++ G Sbjct: 79 IRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALP-YLRKSQG 136 Query: 153 SIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYS---QT 208 +++NI A G AV A + V +TK+LAL+ + G+R+NC++PG I++ + Sbjct: 137 NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEE 196 Query: 209 AVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 + EG + P R+G P EV + FL S A+F TG + V GG L Sbjct: 197 LAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 253 >3EZL-A nrPDB Length = 256 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 115/254 (45%), Gaps = 15/254 (5%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS--RKLERLKSAADELQANLPPTKQA 72 ++ ++A VTGG GIG +I + L + G VV R+K D+ Sbjct: 10 VMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFD----- 64 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 + N+ + + G+I+ LVNN G ++ + W AV++TNL Sbjct: 65 -FYASEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNL 123 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 T F + K V ++ G I+NI + K F +S A+AG++ T SLA E A Sbjct: 124 TSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYS-TAKAGIHGFTMSLAQEVA 182 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 G+ +N V+PG I + + E IP +R+G P+E+ S+V +L S Sbjct: 183 TKGVTVNTVSPGYI----GTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEE 238 Query: 251 ASFITGQSVDVDGG 264 + F TG ++GG Sbjct: 239 SGFSTGADFSLNGG 252 >5B1Y-A nrPDB Length = 270 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 78/261 (29%), Positives = 116/261 (44%), Gaps = 24/261 (9%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERL--KSAADELQANLPPTKQAR 73 ++ A+VTGG+ GIG+A V G +VVIA + L K+A + + P R Sbjct: 21 METTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVR 80 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 V ++ + + V + + +N LVN G L E S W L NLT Sbjct: 81 V-----DVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLT 135 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 G + + K + K SIVN+ I V A++AGV LTK LA++ A Sbjct: 136 GVYLVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAG 195 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK------IPAKRIGVPEEVSSVVCF 245 GIR+N VAP + + +SF + ++ P K I PE+V+ + F Sbjct: 196 YGIRVNAVAPSFVETDMT--------RSFLDTPEKRERIASLHPLKIILKPEDVAEAILF 247 Query: 246 LLSPAASF-ITGQSVDVDGGR 265 L P S ITG + ++ GR Sbjct: 248 LADPRRSRGITGHVLSINAGR 268 >1UZM-A nrPDB Length = 247 Score = 90.5 bits (223), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 68/247 (27%), Positives = 114/247 (46%), Gaps = 21/247 (8%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +VTGG GIG AI + L G V + R K + ++ ++ Sbjct: 19 LVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKG----------------LFGVEVDV 62 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 + + V+ + + G + LV+N G + ++ + + V+ NLTG F + + Sbjct: 63 TDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQR 122 Query: 142 VYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVA 200 S + G ++ I V G + A++AGV + +S+A E + + + N VA Sbjct: 123 ASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVA 182 Query: 201 PGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVD 260 PG I + + + +G+ Q IPAKR+G P EV+ VV FL S AS+I+G + Sbjct: 183 PGYIDTDMTR----ALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIP 238 Query: 261 VDGGRSL 267 VDGG + Sbjct: 239 VDGGMGM 245 >4IIV-A nrPDB Length = 267 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 121/246 (49%), Gaps = 13/246 (5%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE-LQANLPPTKQARVIPIQCN 80 +VTG + GIG+AI ++L G N+ + R + A E L A + R++ + Sbjct: 30 LVTGASKGIGRAIARQLAADGFNIGV---HYHRDAAGAQETLNAIVANGGNGRLLSF--D 84 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCK 140 + N E+ +++ + G +V+N G + +S+ W AV+ TNL + + + Sbjct: 85 VANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQ 144 Query: 141 AVYSSWM-KEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 + GG I+ + V G V+ AA+AG+ TK+LA+E A I +NC Sbjct: 145 PCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNC 204 Query: 199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQS 258 +APG+I + +S + + IP KR+G EEV+ + +L+S A ++T Q Sbjct: 205 IAPGLIDTGMI-----EMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQV 259 Query: 259 VDVDGG 264 + ++GG Sbjct: 260 ISINGG 265 >1O5I-A nrPDB Length = 249 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 120/253 (47%), Gaps = 34/253 (13%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +V + GIG+A+ L + G+ V I +R E LK + + C++ Sbjct: 23 LVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSGHRY--------------VVCDL 68 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 R + ++ + +++ LV N GG + ++++ + +++ + + Sbjct: 69 RKDLDL------LFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRN 122 Query: 142 VYSSWMKEHG-GSIV-----NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 Y MKE G G IV ++I P + + S +AR + K+L+ E A GI Sbjct: 123 -YLPAMKEKGWGRIVAITSFSVISPIENLY----TSNSARMALTGFLKTLSFEVAPYGIT 177 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +NCVAPG ++ E + E +IP +R+ PEE++SVV FL S AS++T Sbjct: 178 VNCVAPGWTETERVKELLSEEKKKQVES---QIPMRRMAKPEEIASVVAFLCSEKASYLT 234 Query: 256 GQSVDVDGGRSLY 268 GQ++ VDGG S + Sbjct: 235 GQTIVVDGGLSKF 247 >3GDF-A nrPDB Length = 267 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 79/268 (29%), Positives = 125/268 (46%), Gaps = 21/268 (7%) Query: 6 KGRSYLAPGLLQGQVAIVTG--GATGIGKAIVKELLELGSNVVI--ASRKLERLKSAADE 61 K S L L+G+V +VTG G G+G + E+G+ V I ASR A+E Sbjct: 8 KHESLLDQLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRA-----QGAEE 62 Query: 62 LQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISS 121 L T + +C + + E LVK + FG+I+ + N G S S Sbjct: 63 NVKELEKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSV 122 Query: 122 KGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAG----FPLAVHS-GAARA 176 + W+ V++ +L GTF+ KAV + + GS+V I + +G FP S A+A Sbjct: 123 EAWNHVVQVDLNGTFHCAKAVGHHFKERGTGSLV--ITASMSGHIANFPQEQTSYNVAKA 180 Query: 177 GVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVP 236 G ++ +SLA EW R+N ++PG Y T + ++ S IP R G+ Sbjct: 181 GCIHMARSLANEWR-DFARVNSISPG--YIDTGLSDFVPKETQQLWHSM--IPMGRDGLA 235 Query: 237 EEVSSVVCFLLSPAASFITGQSVDVDGG 264 +E+ + S A+++ TG + +DGG Sbjct: 236 KELKGAYVYFASDASTYTTGADLLIDGG 263 >3U5T-A nrPDB Length = 267 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/249 (29%), Positives = 114/249 (45%), Gaps = 14/249 (5%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VAIVTG + GIG AI L G VVI K+AA E A + + Q Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVINYAG----KAAAAEEVAGKIEAAGGKALTAQ 83 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ + V L + + FG ++ LVNN G L+ + V+ NL GTF Sbjct: 84 ADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNT 143 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGF--PLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 + ++ GG I+N + ++ G P AA+AGV +T L+ E I + Sbjct: 144 LR--EAAQRLRVGGRIIN-MSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDITV 200 Query: 197 NCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI-PAKRIGVPEEVSSVVCFLLSPAASFIT 255 N VAPG TA + + F K+ P +R+G P++++ V FL P +++ Sbjct: 201 NAVAPG----PTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVN 256 Query: 256 GQSVDVDGG 264 GQ + +GG Sbjct: 257 GQVLRANGG 265 >1DOH-A nrPDB Length = 283 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 66/264 (25%), Positives = 125/264 (47%), Gaps = 19/264 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+VA+VTG GIG+ + EL G V++ +A+E+ A + Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIV---NYANSTESAEEVVAAIKKNGSDAAC 83 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ N+ E++ + + + FGK++ + +N G + ++ + + V N G Sbjct: 84 -VKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQ 142 Query: 136 FYMCKAVYSSWMKEHGGSIV---NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 F++ + Y E GG ++ +I KA AV+SG+ + + + +A++ A Sbjct: 143 FFVAREAYKHL--EIGGRLILMGSITGQAKAVPKHAVYSGS-KGAIETFARCMAIDMADK 199 Query: 193 GIRINCVAPGVIYS---QTAVENYGSWGQSFFE------GSFQKIPAKRIGVPEEVSSVV 243 I +N VAPG I + Y G++ + Q P +R+G+P +++ VV Sbjct: 200 KITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVV 259 Query: 244 CFLLSPAASFITGQSVDVDGGRSL 267 CFL S ++TG+ + +DGG + Sbjct: 260 CFLASNDGGWVTGKVIGIDGGACM 283 >3U4C-A nrPDB Length = 281 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 74/270 (27%), Positives = 133/270 (49%), Gaps = 37/270 (13%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + + A V G + GIGKAI +L + ++VI SR L+ ++S +++ A P +A VI Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHP---EASVI 77 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ ++ + + G+++ L+NN G ++ + + ++T T Sbjct: 78 VLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIE--------DMTAT 129 Query: 136 FYMCKAVY-------SSWMKEHG-GSIVNII--VPTKAGFPLAVHSGAARAGVYNLTKSL 185 F Y SS MK++ G I+NI+ + + G + +S A + N +K++ Sbjct: 130 FTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNS-MMNAALINASKNI 188 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEG---SFQK--------IPAKRIG 234 +++ A I +NC+ PG I A + Y + ++ + S QK IP KR+G Sbjct: 189 SIQLAPHNITVNCLNPGFI----ATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVG 244 Query: 235 VPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 EE +++ FL S AS+ITGQ + DGG Sbjct: 245 SAEETAALAAFLASEEASYITGQQISADGG 274 >5YSS-A nrPDB Length = 256 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/265 (25%), Positives = 124/265 (46%), Gaps = 31/265 (11%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARV 74 L G+ A+VTG +GIG I + L + G+ +++ + +A D + Q P Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQAGATLIL--NGFGDVDAAKDAVAQYGKTPGYHG-- 58 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 ++ +E ++ ++++ FG ++ L+NN G Q +SP E W+A++ NL+ Sbjct: 59 ----ADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSS 114 Query: 135 TFYMCKAVYSSWMKEHGGSIVNI-----IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 F+ + + G I+NI +V +K AA+ GV LTK++ALE Sbjct: 115 VFHTTRLALPGMRARNWGRIINIASVHGLVASKEKSAYV----AAKHGVVGLTKTIALET 170 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGS----------FQKIPAKRIGVPEEV 239 A + I N + PG + + + + EG+ +K P++ PE++ Sbjct: 171 AQTEITCNALCPGWVLTPLVQQQI---DKRIAEGAEPEAARDALLAEKQPSREFVTPEQL 227 Query: 240 SSVVCFLLSPAASFITGQSVDVDGG 264 ++ FL S A+ + G + ++DGG Sbjct: 228 GNLALFLCSDGAAQVRGVAWNMDGG 252 >2Q2Q-A nrPDB Length = 255 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 116/258 (44%), Gaps = 17/258 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA-RV 74 L+G+ A+VTG +GIG I + L G+N+V L D A + + Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIV--------LNGFGDPAPALAEIARHGVKA 53 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++ + ++ L FG ++ LVNN G Q ++P E + W ++ NL+ Sbjct: 54 VHHPADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSA 113 Query: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F+ + + G I+NI V G AA+ GV LTK + LE A S Sbjct: 114 VFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSN 173 Query: 194 IRINCVAPGVIYS---QTAVENYGSWG----QSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 + N + PG + + Q +++ + G Q+ + +K P+ PE + +V FL Sbjct: 174 VTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFL 233 Query: 247 LSPAASFITGQSVDVDGG 264 S A S + G + +VDGG Sbjct: 234 CSEAGSQVRGAAWNVDGG 251 >4CQL-A nrPDB Length = 261 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 85/276 (30%), Positives = 127/276 (46%), Gaps = 30/276 (10%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 MAS + R L+ +A+VTG +GIG+A+ L G +A+ L+R +AA Sbjct: 1 MASQLQNR-------LRSALALVTGAGSGIGRAVSVRLA--GEGATVAACDLDR--AAAQ 49 Query: 61 ELQANL--PPTKQA----RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG---- 110 E L P +K+ Q ++ L++ F + +V + G Sbjct: 50 ETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD 109 Query: 111 QFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG-GSIVNII-VPTKAGFPLA 168 +FL H+S W V+ NL GTF + +A + + GSI+NI + K G Sbjct: 110 EFLL---HMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQ 166 Query: 169 VHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI 228 + A++AGV LT++ A E GIR N V PG I A Q + + I Sbjct: 167 TNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFI----ATPMTQKVPQKVVDKITEMI 222 Query: 229 PAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 P +G PE+V+ VV FL S + +ITG SV+V GG Sbjct: 223 PMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 >3PPI-A nrPDB Length = 281 Score = 84.3 bits (207), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 75/264 (28%), Positives = 130/264 (49%), Gaps = 33/264 (12%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 +G AIV+GGA G+G+A V+ L G VVIA E+ K+ ADEL R Sbjct: 28 FEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADEL--------GNRAE 79 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK--------GWHAV 127 + N+ +E+ V +++ + G++ + V GG A+ I + G+ Sbjct: 80 FVSTNVTSEDSVLAAIEAA-NQLGRLRYAVVAHGG--FGVAQRIVQRDGSPADMGGFTKT 136 Query: 128 LETNLTGTFYMCKAVYSSWM----KEHGGSIVNIIVPTKAGFPLAVHS---GAARAGVYN 180 ++ L GT+ + + V +S +E+G ++ + AG+ + AA+AGV Sbjct: 137 IDLYLNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIG 196 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEV 239 LT + A + + +GIR+N +APG + + +E+ G + F + IP KR+G P+E Sbjct: 197 LTIAAARDLSSAGIRVNTIAPGTMKTPI-MESVGEEALAKFAAN---IPFPKRLGTPDEF 252 Query: 240 SSVVCFLLSPAASFITGQSVDVDG 263 + FLL+ +I G+ + +DG Sbjct: 253 ADAAAFLLTN--GYINGEVMRLDG 274 >1HXH-A nrPDB Length = 253 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 73/254 (28%), Positives = 126/254 (49%), Gaps = 19/254 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+VA+VTGGA+G+G +VK LL G+ V + ++A +L A L R + Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDIN----EAAGQQLAAELGE----RSM 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ ++ +E + ++ + G +N LVNN G E + + +L+ N Sbjct: 56 FVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESV 115 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSG--AARAGVYNLTKSLALEWACSG 193 F C+ ++ MKE GGSI+N + + P+ ++G A++A V LT++ AL G Sbjct: 116 FIGCQQGIAA-MKETGGSIIN-MASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQG 173 Query: 194 --IRINCVAPGVIYS---QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 IR+N + P IY+ Q ++ S + + A R +PE ++ +V FL S Sbjct: 174 YAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNR--AGRAYMPERIAQLVLFLAS 231 Query: 249 PAASFITGQSVDVD 262 +S ++G + D Sbjct: 232 DESSVMSGSELHAD 245 >3R3S-A nrPDB Length = 294 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 124/262 (47%), Gaps = 9/262 (3%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 +SY+ G L+ + A+VTGG +GIG+A G++V I L + A +++A + Sbjct: 39 KSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAI--NYLPAEEEDAQQVKALIE 96 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA-EHISSKGWHA 126 + V+ + ++ +E +LV + G ++ L G Q P + ++S+ + Sbjct: 97 ECGRKAVL-LPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQ 155 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSL 185 N+ F++ + K G SI+ + P + A +A + N ++ L Sbjct: 156 TFAVNVFALFWITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGL 213 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 A + A GIR+N VAPG I+ TA++ G Q Q+ P KR G P E++ V + Sbjct: 214 AKQVAEKGIRVNIVAPGPIW--TALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVY 271 Query: 246 LLSPAASFITGQSVDVDGGRSL 267 L S +S++T + V GG L Sbjct: 272 LASQESSYVTAEVHGVCGGEHL 293 >3A28-C nrPDB Length = 258 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 14/256 (5%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA+VTGGA GIG+ I ++L G ++ +A ++ + AA+ ++ L + + + Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLP-QQEEQAAETIK--LIEAADQKAVFVG 59 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ ++ ++ + + G + LVNN G + P ++ + + N+ F+ Sbjct: 60 LDVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFG 119 Query: 139 CKAVYSSW--MKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 +A + + G I + GFP+ + V LT++ A E A G + Sbjct: 120 IQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTV 179 Query: 197 NCVAPGVI----YSQTAVE----NYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 N APG++ + Q E N G++F E S I R VPE+V+ +V FL S Sbjct: 180 NAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYS-SSIALGRPSVPEDVAGLVSFLAS 238 Query: 249 PAASFITGQSVDVDGG 264 ++++TGQ + VDGG Sbjct: 239 ENSNYVTGQVMLVDGG 254 >4TRR-A nrPDB Length = 269 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 15/259 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG A+GIGK I EL + G+ V IA + + ADE+ + I Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEIN-----KAGGKAI 66 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ NEE VN + + FG ++ LV+N G Q ++P E+ S W + ++ G Sbjct: 67 GVAMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGA 126 Query: 136 FYMCKAVYSSWMKEHGGSIVNII--VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F KA K+ G +V + V + PL A+ G+ L + LA E A Sbjct: 127 FLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHN 186 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIG--------VPEEVSSVVCF 245 +R + V PG + + + + + I +G ++V+ V F Sbjct: 187 VRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLF 246 Query: 246 LLSPAASFITGQSVDVDGG 264 L + ++ +TGQS V G Sbjct: 247 LSAFPSAALTGQSFIVSHG 265 >2NWQ-A nrPDB Length = 272 Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 55/235 (23%), Positives = 115/235 (48%), Gaps = 13/235 (5%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +TG +G G+A + E G ++V+ R+ ERL++ A EL A + RV+P+ ++ Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSA------KTRVLPLTLDV 78 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQF-LSPAEHISSKGWHAVLETNLTGTFYMCK 140 R+ ++ V + + F + L+NN G PA+ W +++TN+ G Y + Sbjct: 79 RDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTR 138 Query: 141 AVYSSWMKE-HGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 + + G SIVN+ V K +P + G +A V + +L + +G+R+ Sbjct: 139 LLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTN 198 Query: 199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 + PG+ S+ ++ +G Q+ ++ ++ + PE+++ + ++++ A Sbjct: 199 LEPGLCESEFSLVRFGG-DQARYDKTYAGAHPIQ---PEDIAETIFWIMNQPAHL 249 >5EJ2-A nrPDB Length = 308 Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 74/276 (26%), Positives = 125/276 (45%), Gaps = 23/276 (8%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS-----RKLERLKSAADEL--QANL 66 G + G+VA ++G A G G++ L + G++++ L S ++L A+L Sbjct: 33 GRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADL 92 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWH 125 R++ Q ++R+ E + + V S ++ G+++ +V N G G I W Sbjct: 93 VKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQ 152 Query: 126 AVLETNLTGTFYMCKA-VYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTK 183 +++ NLTG ++ KA V GGSIV V + +P H AA+ GV L + Sbjct: 153 DMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMR 212 Query: 184 SLALEWACSGIRINCVAPG------VIYSQT------AVENYGSWGQSFFEGSFQKIPAK 231 + A+E IR+N V P V+ QT +EN G + +P Sbjct: 213 AFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP 272 Query: 232 RIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 + ++S+ V FL S + ++TG S+ VD G L Sbjct: 273 WVDA-SDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >5JY1-A nrPDB Length = 274 Score = 80.5 bits (197), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 76/280 (27%), Positives = 128/280 (45%), Gaps = 31/280 (11%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 GLL+ +VA+VTG GIG+ + + G+ V+IA + E++ R Sbjct: 10 GLLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIR-----EMGGR 64 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA-----EHISSKGWHAVL 128 + ++ ++ ++ + V+S ++ FG ++ LVNN P E + + L Sbjct: 65 SLFVKTDVTSKASIEAAVRSAVEQFGSLDILVNNA----FVPTPNVLLEEKTDEMLEQTL 120 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 T+L T++ +A + + G IVN + T+ G L A+AG+ LT+S A Sbjct: 121 TTSLWATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAAS 180 Query: 188 EWACSGIRINCVAP---GVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPE-EVSSVV 243 EW I +N +AP G + + A +N F E S P R G PE ++ Sbjct: 181 EWGRFNITVNAIAPTAMGATFFELAAKN-----PEFAERSAAARPLGRSGDPEQDIGPAA 235 Query: 244 CFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 283 F S + F+TG+++ VDGG L P +++ P G Sbjct: 236 VFFASEMSRFVTGETLHVDGGLHL-------PGYNSRPAG 268 >2FWM-X nrPDB Length = 250 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 111/256 (43%), Gaps = 30/256 (11%) Query: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIR 82 VTG GIG A +E G+ V + Q P + ++ Sbjct: 12 VTGAGKGIGYATALAFVEAGAKVTGFDQAFT---------QEQYPFATEV------MDVA 56 Query: 83 NEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAV 142 + +V + + L +++ LVN G + + +S + W N+ G F + + Sbjct: 57 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 116 Query: 143 YSSWMKEHGGSIVNIIVPTKAGFPLAVHS-GAARAGVYNLTKSLALEWACSGIRINCVAP 201 + + ++ GG+IV + + + + GA++A + +L S+ LE A SG+R N V+P Sbjct: 117 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 176 Query: 202 GV----------IYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 G + + +G+ F G IP +I P+E+++ + FL S A Sbjct: 177 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLG----IPLGKIARPQEIANTILFLASDLA 232 Query: 252 SFITGQSVDVDGGRSL 267 S IT Q + VDGG +L Sbjct: 233 SHITLQDIVVDGGSTL 248 >2GDZ-A nrPDB Length = 267 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 62/215 (28%), Positives = 101/215 (46%), Gaps = 26/215 (12%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 ++ G+VA+VTG A GIG+A + LL G+ V + LE L P K Sbjct: 4 MVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQK---T 60 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + IQC++ +++++ + + +D FG+++ LVNN G + K W L+ NL Sbjct: 61 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVS 112 Query: 135 TF---YMCKAVYSSWMKEHGGSIVNIIVPTKAGF-PLAVHS--GAARAGVYNLTKS--LA 186 Y+ S GG I+N+ + AG P+A A++ G+ T+S LA Sbjct: 113 VISGTYLGLDYMSKQNGGEGGIIINM--SSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 170 Query: 187 LEWACSGIRINCVAPG-----VIYSQTAVENYGSW 216 SG+R+N + PG ++ S EN G + Sbjct: 171 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQY 205 >4EGF-A nrPDB Length = 266 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 69/254 (27%), Positives = 111/254 (43%), Gaps = 8/254 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A++TG GIG I + G+ +V++ R + L +A L V Sbjct: 18 LDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQF----GTDVH 73 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ + L + + FG ++ LVNN G P + + A + NL Sbjct: 74 TVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAP 133 Query: 136 FYMCKAVYSSWMKE-HGGSIVNIIVPTKAGFPLAVHS-GAARAGVYNLTKSLALEWACSG 193 + AV + + GG+I+ + ++ ++AG+ TK LA E G Sbjct: 134 ALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHG 193 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR N V P V+ ++ +G +S +IP R VP EVS V +L S AAS Sbjct: 194 IRANSVCPTVVLTEMGQRVWGDEAKS--APMIARIPLGRFAVPHEVSDAVVWLASDAASM 251 Query: 254 ITGQSVDVDGGRSL 267 I G + VDGG ++ Sbjct: 252 INGVDIPVDGGYTM 265 >3RKU-A nrPDB Length = 287 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 105/215 (48%), Gaps = 10/215 (4%) Query: 4 WAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGS---NVVIASRKLERLKSAAD 60 ++GR A L + ++TG + GIGKA E LE + +++A+R+LE+L+ Sbjct: 21 MSQGRK--AAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKK 78 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP-AEHI 119 + P A+V Q +I E++ +++ F I+ LVNN G S I Sbjct: 79 TIDQEFP---NAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQI 135 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGV 178 +++ V +TN+T + +AV + ++ G IVN+ + + +P A++ V Sbjct: 136 ATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAV 195 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENY 213 T SL E + IR+ +APG++ ++ ++ Y Sbjct: 196 GAFTDSLRKELINTKIRVILIAPGLVETEFSLVRY 230 >5O3Z-A nrPDB Length = 263 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 70/263 (26%), Positives = 122/263 (46%), Gaps = 19/263 (7%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 QVA+V GG +G + + L + G +V +A AD + + R + Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGA---GRAYGFK 63 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 + +E V L ++ +TFG+ + LV + G +P + L+ NL G +++ Sbjct: 64 VDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVG-YFL 122 Query: 139 CKAVYSSWMKEHG--GSIVNIIVPTKAGFPLAVHSG---AARAGVYNLTKSLALEWACSG 193 C +S M G G I+ I +K+G + H+ AA+ G LT+SLAL+ A G Sbjct: 123 CSREFSKLMIRDGIKGRIIQI--NSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYG 180 Query: 194 IRINCVAPGVIYS----QTAVENY----GSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 I ++ + G + Q+ + Y G + K+P KR ++V +V+ F Sbjct: 181 ITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLF 240 Query: 246 LLSPAASFITGQSVDVDGGRSLY 268 S A++ TGQS++V GG+ ++ Sbjct: 241 YASDKAAYCTGQSINVTGGQVMF 263 >3UVE-A nrPDB Length = 286 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/287 (23%), Positives = 126/287 (43%), Gaps = 41/287 (14%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVV----------------IASRKLERLKS 57 G ++G+VA VTG A G G++ L + G++++ I + E L Sbjct: 7 GRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAE 66 Query: 58 AADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPA 116 AD ++ + R++ + ++R+ + + V S ++ G+++ +V N G G Sbjct: 67 TADLVKGH-----NRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTL 121 Query: 117 EHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAG----FPLAVHSG 172 + S + W +++ NL G + KA + GG +II+ + G +P H Sbjct: 122 DKTSEEDWTEMIDINLAGVWKTVKAGVPHMIA--GGRGGSIILTSSVGGLKAYPHTGHYV 179 Query: 173 AARAGVYNLTKSLALEWACSGIRINCVAPGVIYS------------QTAVENYGSWGQSF 220 AA+ GV L ++ +E IR+N V P + + + +EN G + Sbjct: 180 AAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAP 239 Query: 221 FEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 F +P + P ++S+ V F S A +ITG ++ +D G L Sbjct: 240 ICQMFHTLPIPWV-EPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >2X9N-A nrPDB Length = 288 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 85/285 (29%), Positives = 123/285 (43%), Gaps = 53/285 (18%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIA-SRKLERLKSAADEL-----------Q 63 ++ A+VTG A IG+AI +L + G VVI E S ADEL Q Sbjct: 21 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQ 80 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP---AEHIS 120 A+L + V+P C EE+ + S FG+ + LVNN + +P +H Sbjct: 81 ADL---TNSNVLPASC-----EEI---INSCFRAFGRCDVLVNNASAFYPTPLVQGDHED 129 Query: 121 SK-------------GWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPL 167 + G +A+ LT +F + + SIVN+ P Sbjct: 130 NSNGKTVETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNL-CDAMVDQPC 188 Query: 168 AVHS--GAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAV--ENYGSWGQSFFEG 223 S + + LT+S ALE A GIR+N VAPGV A+ E W Sbjct: 189 MAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKW------- 241 Query: 224 SFQKIP-AKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 +K+P +R E+++ V FL+S +A +ITG + VDGG SL Sbjct: 242 -RRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >3T7C-A nrPDB Length = 299 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/277 (23%), Positives = 132/277 (47%), Gaps = 31/277 (11%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS--RKLERLK---SAADELQANLPP 68 G ++G+VA +TG A G G++ L G++++ ++L+ +K S D+L + Sbjct: 24 GKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQ 83 Query: 69 TKQ--ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG----GQFLSPAEHISSK 122 + R+I Q ++R+ + + V + G+++ ++ N G L+ + K Sbjct: 84 VEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLN---RMDPK 140 Query: 123 GWHAVLETNLTGTFYMCKAVYSSWMK-EHGGSIVNIIVPTKAGFPLAVHSG---AARAGV 178 W +++ NL G + + M + GGSIV + G A + G A++ G+ Sbjct: 141 TWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIV--FTSSIGGLRGAENIGNYIASKHGL 198 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVE--NYGSWGQSFFEGSFQ--KIPAKRIG 234 + L +++ALE IR+N V P + + + Y + + + ++ ++++ Sbjct: 199 HGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMH 258 Query: 235 V-------PEEVSSVVCFLLSPAASFITGQSVDVDGG 264 V P ++S+ + FL+S A +ITG S+ VDGG Sbjct: 259 VLPIPYVEPADISNAILFLVSDDARYITGVSLPVDGG 295 >3V8B-A nrPDB Length = 283 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 70/267 (26%), Positives = 118/267 (44%), Gaps = 32/267 (11%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA++TG +GIG+A L G V R ++ ADE+ + I ++ Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVG-----AGGQAIALEA 84 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ +E ++ N V+ + FG ++ +V N G +P + + W + NL GTF Sbjct: 85 DVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLT 144 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGF-----PLAVHSGAARAGVYNLTKSLALEWACSG 193 + ++K+ GG + ++V + G P A A +A + + LALE Sbjct: 145 LH-LTVPYLKQRGGGAI-VVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHH 202 Query: 194 IRINCVAPGVIYS------------QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSS 241 IR+N V PG I + +TA+ GQ I + G E+V+ Sbjct: 203 IRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQV-------PITDGQPGRSEDVAE 255 Query: 242 VVCFLLSPAASFITGQSVDVDGGRSLY 268 ++ FL+S A +TG V +DGG+ L Sbjct: 256 LIRFLVSERARHVTGSPVWIDGGQGLL 282 >4GKB-A nrPDB Length = 258 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 85/273 (31%), Positives = 123/273 (45%), Gaps = 43/273 (15%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQ +V IVTGGA+GIG AI L E + V+ +R A D + +Q R Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARH------APDGAFLDALAQRQPRAT 58 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG---GQFLSPAEHISSKGWHAVLETNL 132 + ++++ + + V T+ TFG+++ LVNN G G L + A LE NL Sbjct: 59 YLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGR----DAFVASLERNL 114 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTK----SLALE 188 + M +K G+IVNI T +G Y +K +L E Sbjct: 115 IHYYAMAHYCVPH-LKATRGAIVNISSKTAV-------TGQGNTSGYCASKGAQLALTRE 166 Query: 189 WACS----GIRINCVAPGVIYSQTAVENYGSWGQSFF--EGSFQKIPAK-----RIGVPE 237 WA + G+R+N V P + + Y +W +F E +I AK R P+ Sbjct: 167 WAVALREHGVRVNAVIPAEVMTPL----YRNWIATFEDPEAKLAEIAAKVPLGRRFTTPD 222 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDGGRSLYTH 270 E++ FLLSP AS TG+ + VDGG YTH Sbjct: 223 EIADTAVFLLSPRASHTTGEWLFVDGG---YTH 252 >1P33-A nrPDB Length = 289 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 87/290 (30%), Positives = 128/290 (44%), Gaps = 54/290 (18%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD--ELQANLPPTKQARVIPI 77 VA+VTG A +G +I + L G V L +SAAD L A L + I + Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVC-----LHYHRSAADASTLAATLNARRPNSAITV 63 Query: 78 QCNIRNE-----------------EEVNNLVKSTLDTFGKINFLVNNGGGQFLSP----- 115 Q ++ N + LV + +G+ + LVNN + +P Sbjct: 64 QADLSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKD 123 Query: 116 -AEHISSKGWHAVLE--------TNLTGTFYMCKA----VYSSWMKEHGGS--IVNIIVP 160 E SS G LE +N +++ KA V + ++ G S IVN+ V Sbjct: 124 AGEGGSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNM-VD 182 Query: 161 TKAGFPLAVHS--GAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQ 218 PL ++ A+ + LT+S ALE A IR+N V+PG+ + + + + Sbjct: 183 AMTSQPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL----SVLPDDMPF-- 236 Query: 219 SFFEGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 S E +K+P +R EEVS VV FL SP A +ITG + VDGG SL Sbjct: 237 SVQEDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >4DA9-A nrPDB Length = 280 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 55/202 (27%), Positives = 93/202 (46%), Gaps = 9/202 (4%) Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK--GWHAVLE 129 ARVI ++ ++ + V + + FG+I+ LVNN G + + + K + ++ Sbjct: 79 ARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVG 138 Query: 130 TNLTGTFYMCKAVYSSWMKEHGG---SIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSL 185 NL GT + +AV + + SI+NI V P + ++AG+ ++ L Sbjct: 139 VNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGL 198 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 AL A +GI + V PG+I S G + E +P +R G PE++ ++V Sbjct: 199 ALRLAETGIAVFEVRPGIIRSDMTAAVSGKY-DGLIESGL--VPMRRWGEPEDIGNIVAG 255 Query: 246 LLSPAASFITGQSVDVDGGRSL 267 L F TG + DGG S+ Sbjct: 256 LAGGQFGFATGSVIQADGGLSI 277 >1CYD-A nrPDB Length = 244 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 63/251 (25%), Positives = 107/251 (42%), Gaps = 17/251 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G A+VTG GIG+ VK L G+ VV +R L S A E + Sbjct: 5 FSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG---------IE 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 P+ ++ + + + L G ++ LVNN + P ++ + + NL Sbjct: 56 PVCVDLGDWDA----TEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSV 111 Query: 136 FYMCKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + + V + GSIVN+ + FP + + + + LTK++A+E Sbjct: 112 FQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHK 171 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+N V P V+ T + S F ++ P ++ E+V + + FLLS ++ Sbjct: 172 IRVNSVNPTVVL--TDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSAS 229 Query: 254 ITGQSVDVDGG 264 +G + VD G Sbjct: 230 TSGGGILVDAG 240 >2BGM-A nrPDB Length = 278 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 62/235 (26%), Positives = 105/235 (44%), Gaps = 13/235 (5%) Query: 36 KELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP-IQCNIRNEEEVNNLVKST 94 K + G+ VVIA A D Q VI + C++ +E+V NLV +T Sbjct: 34 KLFVRYGAKVVIAD-------IADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTT 86 Query: 95 LDTFGKINFLVNNGGGQFLSPAEHISS--KGWHAVLETNLTGTFYMCKAVYSSWMKEHGG 152 + GK++ + N G +P + + + + V++ N+ G F + K + G Sbjct: 87 IAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKG 146 Query: 153 SIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAV 210 SIV I AG ++ A + V LT SL E GIR+NCV+P ++ S Sbjct: 147 SIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLT 206 Query: 211 ENYGSWGQSFFEGSFQKIPAK-RIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 + +G E + Q K + E+V+ V +L + +++G ++ +DGG Sbjct: 207 DVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGG 261 >3D3W-A nrPDB Length = 244 Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 63/253 (24%), Positives = 109/253 (43%), Gaps = 19/253 (7%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L G+ +VTG GIG+ V+ L G+ VV SR L S E + Sbjct: 4 FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG---------I 54 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 P+ ++ + E + L + G ++ LVNN L P ++ + + E NL Sbjct: 55 EPVCVDLGDWEA----TERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRA 110 Query: 135 TFYMCKAVYSSWM-KEHGGSIVNII--VPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 + + V + + G+IVN+ +A +V+ + + + LTK +ALE Sbjct: 111 VIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYC-STKGALDMLTKVMALELGP 169 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 IR+N V P V+ + + ++ + +IP + E V + + FLLS + Sbjct: 170 HKIRVNAVNPTVVMTSMGQATWSDPHKA--KTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227 Query: 252 SFITGQSVDVDGG 264 TG ++ V+GG Sbjct: 228 GMTTGSTLPVEGG 240 >3ZV3-A nrPDB Length = 281 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 71/271 (26%), Positives = 115/271 (42%), Gaps = 41/271 (15%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+VA++TGGA+G+G+A+V + G+ V + + ERL+ EL+ + Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLR----ELEV----AHGGNAV 54 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA-----EHISSKGWHAVLET 130 + ++R+ ++ + L FGKI+ L+ N G S A E + + Sbjct: 55 GVVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHV 114 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF------PLAVHSGAARAGVYNLTKS 184 N+ G + KA + + G + I + AGF PL A + V L + Sbjct: 115 NVKGYIHAVKACLPALVSSRGSVVFTI---SNAGFYPNGGGPLYT---ATKHAVVGLVRQ 168 Query: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----------RIG 234 +A E A +R+N VAPG + T + S G S E S +P R+ Sbjct: 169 MAFELAPH-VRVNGVAPGGM--NTDLRGPSSLGLS--EQSISSVPLADMLKSVLPIGRMP 223 Query: 235 VPEEVSSVVCFLLSPAASF-ITGQSVDVDGG 264 EE + F + S TG ++ DGG Sbjct: 224 ALEEYTGAYVFFATRGDSLPATGALLNYDGG 254 >2BFA-A nrPDB Length = 288 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 82/288 (28%), Positives = 121/288 (42%), Gaps = 50/288 (17%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA+VTG A +G++I + L G V + R + A+ L A L + I +Q Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCL---HYHRSAAEANALSATLNARRPNSAITVQA 64 Query: 80 NIRNE-----------------EEVNNLVKSTLDTFGKINFLVNNGGGQFLSP------A 116 ++ N LV + +G+ + LVNN + +P Sbjct: 65 DLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDED 124 Query: 117 EHISSKGWHAVLET--------NLTGTFYMCKA----VYSSWMKEHGG--SIVNIIVPTK 162 H G +ET N +++ KA V + K G SI+N+ V Sbjct: 125 GHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINM-VDAM 183 Query: 163 AGFPLAVHS--GAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSF 220 PL ++ A+ + LT+S ALE A IR+N V PG+ V++ + Sbjct: 184 TNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL---SVLVDD---MPPAV 237 Query: 221 FEGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 +EG K+P +R EVS VV FL S A +ITG V VDGG SL Sbjct: 238 WEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >2AG5-A nrPDB Length = 246 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 8/184 (4%) Query: 92 KSTLDTFG----KINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWM 147 K +D F +++ L N G K W + N+ + M KA + Sbjct: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 Query: 148 KEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIY 205 + G+I+N+ + + G +A V LTKS+A ++ GIR NCV PG + Sbjct: 122 AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVD 181 Query: 206 SQTAVENYGSWG--QSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDG 263 + + E + G + ++ R EE++ + +L S ++++TG V +DG Sbjct: 182 TPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDG 241 Query: 264 GRSL 267 G SL Sbjct: 242 GWSL 245 >2QHX-A nrPDB Length = 328 Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 82/288 (28%), Positives = 121/288 (42%), Gaps = 50/288 (17%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA+VTG A +G++I + L G V + R + A+ L A L + I +Q Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCL---HYHRSAAEANALSATLNARRPNSAITVQA 104 Query: 80 NIRNE-----------------EEVNNLVKSTLDTFGKINFLVNNGGGQFLSP------A 116 ++ N LV + +G+ + LVNN + +P Sbjct: 105 DLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDED 164 Query: 117 EHISSKGWHAVLET--------NLTGTFYMCKA----VYSSWMKEHGG--SIVNIIVPTK 162 H G +ET N +++ KA V + K G SI+N+ V Sbjct: 165 GHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINM-VDAM 223 Query: 163 AGFPLAVHS--GAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSF 220 PL ++ A+ + LT+S ALE A IR+N V PG+ V++ + Sbjct: 224 TNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL---SVLVDD---MPPAV 277 Query: 221 FEGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 +EG K+P +R EVS VV FL S A +ITG V VDGG SL Sbjct: 278 WEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2YW9-A nrPDB Length = 261 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 66/258 (25%), Positives = 114/258 (44%), Gaps = 21/258 (8%) Query: 16 LQGQVAIVTG--GATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L G+ A+V G +G AI +L E G+ V + S + ERL+ A++L L Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVAL-SYQAERLRPEAEKLAEAL-----GG 59 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK-------GWHA 126 + + ++ +EE++ L + FG +++LV+ +P E + + W Sbjct: 60 ALLFRADVTQDEELDALFAGVKEAFGGLDYLVH---AIAFAPREAMEGRYIDTRRQDWLL 116 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 LE + + + ++E GG + ++ P A+A + + LA Sbjct: 117 ALEVSAYSLVAVARRA-EPLLREGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLA 175 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 E G+R+N ++ G + + A G ++ Q P +R EEV ++ FL Sbjct: 176 YELGPKGVRVNAISAGPVRTVAARSIPGF--TKMYDRVAQTAPLRRNITQEEVGNLGLFL 233 Query: 247 LSPAASFITGQSVDVDGG 264 LSP AS ITG+ V VD G Sbjct: 234 LSPLASGITGEVVYVDAG 251 >1BDB-A nrPDB Length = 277 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 26/203 (12%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ ++TGGA+G+G+A+V + G+ V + + ERL A L V+ Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERL--------AELETDHGDNVL 54 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-----GQFLSPAEHISSKGWHAVLET 130 I ++R+ E+ + FGKI+ L+ N G + E + V Sbjct: 55 GIVGDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHI 114 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF------PLAVHSGAARAGVYNLTKS 184 N+ G + KA + + G I I + AGF PL AA+ + L + Sbjct: 115 NVKGYIHAVKACLPALVASRGNVIFTI---SNAGFYPNGGGPLYT---AAKHAIVGLVRE 168 Query: 185 LALEWACSGIRINCVAPGVIYSQ 207 LA E A +R+N V G I S Sbjct: 169 LAFELAPY-VRVNGVGSGGINSD 190 >5ILO-A nrPDB Length = 271 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 99/225 (44%), Gaps = 47/225 (20%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR-- 73 +G+ A+VTGGA GIG + K+LL G+ K A +LQ NL + R Sbjct: 13 FRGKNAVVTGGAGGIGLQVSKQLLAAGA-----------AKVAIIDLQDNLEEFVKLRAA 61 Query: 74 -----VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 V+ I+ ++ N++ V + TFG I+ +VN G + K L Sbjct: 62 HPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAG--------IFNDKDVQRTL 113 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGS---IVNI--IVPTKAGFPLAVHSGAARAGVYNLTK 183 NL G + K++GG +VN+ +V F + V+ GA +AG+ N T+ Sbjct: 114 LVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVY-GATKAGIINFTR 172 Query: 184 SLALE--WACSGIRINCVAPG-------------VIYSQTAVENY 213 LA E + SGI+ V PG +I+ +T+ E Y Sbjct: 173 CLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETY 217 >1E3W-A nrPDB Length = 261 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/264 (24%), Positives = 117/264 (44%), Gaps = 32/264 (12%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 ++G VA++TGGA+G+G + K L+ G+ V+ ++ A +L N I Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN--------CI 59 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA------VLE 129 N+ +E+EV + + FG+I+ VN G H H V+ Sbjct: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 Query: 130 TNLTGTFYMCKAVYSSWMK---EHGGS---IVNIIVPTKAGFPLAVHSG---AARAGVYN 180 NL GTF + + V + + GG I+N + A F V A++ G+ Sbjct: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIIN--TASVAAFEGQVGQAAYSASKGGIVG 177 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEV 239 +T +A + A GIR+ +APG +++ + ++F ++P R+G P E Sbjct: 178 MTLPIARDLAPIGIRVVTIAPG-LFATPLLTTLPDTVRNFLA---SQVPFPSRLGDPAEY 233 Query: 240 SSVVCFLLSPAASFITGQSVDVDG 263 + +V ++ F+ G+ + +DG Sbjct: 234 AHLVQMVIE--NPFLNGEVIRLDG 255 >5YCX-A nrPDB Length = 266 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 69/267 (25%), Positives = 120/267 (44%), Gaps = 35/267 (13%) Query: 15 LLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVI--ASRKLER-LKSAADELQANLPPT 69 LLQG+ +V G A I I + L G+ ++ A +LER ++ AD L+ Sbjct: 5 LLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEG----- 59 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLV--------NNGGGQFLSPAEHISS 121 +++ V+P C++ N+EE+ ++ G I+ + ++ G+F+ S Sbjct: 60 QESLVLP--CDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDT----SR 113 Query: 122 KGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS----GAARAG 177 G+ +L N++ A + + GG NI+ T G V + G A+A Sbjct: 114 DGF--LLAQNISAFSLTAVAREAKKVMTEGG---NILTLTYLGGERVVKNYNVMGVAKAS 168 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPE 237 + K LA + GIR+N ++ G I + +A + G + S ++ P +R E Sbjct: 169 LEASVKYLANDLGQHGIRVNAISAGPIRTLSA-KGVGDF-NSILREIEERAPLRRTTTQE 226 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDGG 264 EV FL S A +TG+++ VD G Sbjct: 227 EVGDTAVFLFSDLARGVTGENIHVDSG 253 >4RGB-A nrPDB Length = 294 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 66/273 (24%), Positives = 111/273 (40%), Gaps = 26/273 (9%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVV---------IASRKLERLKSAADELQA 64 G L G+V +TG A G G++ E G+N+V I KL + E A Sbjct: 21 GSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEEL--EETA 78 Query: 65 NLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGW 124 L ++ + ++R++ + + + ++ FG I+ ++ N G +P E +S+ Sbjct: 79 RLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEAL 138 Query: 125 HAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSG--------AARA 176 L+ L G + + V MKE G N+I + L + G ++ Sbjct: 139 RLGLDIMLIGVWNTFQ-VAIPHMKERGQG-GNLIATSSMIALLDLTDGRGGTDAYLTSKL 196 Query: 177 GVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSW-----GQSFFEGSFQKIPAK 231 + L +S AL A IR+N VAP + EN + +P Sbjct: 197 AITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDF 256 Query: 232 RIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 + P +VS+ + FL+S A TG + VD G Sbjct: 257 PMIEPRDVSNAILFLISDAGRSFTGSVLKVDAG 289 >5IZ4-A nrPDB Length = 271 Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 64/259 (24%), Positives = 116/259 (44%), Gaps = 23/259 (8%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V ++TG A+GIG A + G +V I + + + AA ++A L A+ + Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFD-DSTRDAASTVEA-LCRDAGAQTLIFDA 73 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA---EHISSKGWHAVLETNLTGTF 136 ++ + + + V + +I+ L+N G + P + I + V NL G + Sbjct: 74 DVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLY 133 Query: 137 YMCKA----VYSSWMKEHGGSIVNIIVPTKAGFP---LAVHSGAARAGVYNLTKSLALEW 189 M +A + S S+VN V + AG ++ A++ V LT SLA Sbjct: 134 QMTRAAVPLLRESASATRSTSVVN--VSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNL 191 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI----PAKRIGVPEEVSSVVCF 245 A IR+N +APG++ + + + ++G ++ P KR+ P E++ + F Sbjct: 192 A-PHIRVNALAPGMVDDGLLLRVLDA---AAYDGVLSRMTESAPLKRVSRPAEIAELAWF 247 Query: 246 LLSPAASFITGQSVDVDGG 264 L + A + ITGQ + + G Sbjct: 248 LTAHAPA-ITGQVIAAENG 265 >4DRY-A nrPDB Length = 281 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 58/190 (30%), Positives = 94/190 (49%), Gaps = 15/190 (7%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 +G++A+VTGG TG+G+ I + L G +VVI R+ + L +AA E+ +A V Sbjct: 32 EGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVV-- 89 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS-PAEHISSKGWHAVLETNLTGT 135 C++ + ++V L + F +++ LVNN G P E ++ + W+ ++ NLTG Sbjct: 90 --CDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGA 147 Query: 136 FYMCKAVYSSWMKEH---GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLAL---- 187 F +C MK GG I+N + + P + A + + LTKS AL Sbjct: 148 F-LCTQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRM 206 Query: 188 -EWACSGIRI 196 + AC I I Sbjct: 207 HDIACGQIDI 216 >3OIG-A nrPDB Length = 266 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 71/274 (25%), Positives = 114/274 (41%), Gaps = 51/274 (18%) Query: 16 LQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L+G+ +V G A I I + L E G+ ++ + ERL+ + EL L Sbjct: 5 LEGRNIVVMGVANKRSIAWGIARSLHEAGARLIF-TYAGERLEKSVHELAGTLDRNDS-- 61 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKIN-----------------FLVNNGGGQFLSPA 116 I + C++ N+ E+ S + G I+ +L N G L A Sbjct: 62 -IILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLL--A 118 Query: 117 EHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS----G 172 +ISS AV++ + M GGSIV + T G L + + G Sbjct: 119 HNISSYSLTAVVKA-------------ARPMMTEGGSIVTL---TYLGGELVMPNYNVMG 162 Query: 173 AARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPA 230 A+A + K LA + IR+N ++ G I + +A + ++ S + E + P Sbjct: 163 VAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEE----RAPL 218 Query: 231 KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 +R PEEV FL S + ITG+++ VD G Sbjct: 219 RRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSG 252 >2HRB-A nrPDB Length = 274 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 46/141 (32%), Positives = 66/141 (46%), Gaps = 10/141 (7%) Query: 19 QVAIVTGGATGIGKAIVKELL-ELGSNVVIASRKLERLKSAADELQAN-LPPTKQARVIP 76 +VA+VTG GIG AI +EL + +VV+ +R + R ++A +LQA L P Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFH----- 57 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 Q +I + + + L +G +N LVNN F S L+TN T Sbjct: 58 -QLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATR 116 Query: 137 YMCKAVYSSWMKEHGGSIVNI 157 MC + MK H G +VNI Sbjct: 117 NMCNELL-PIMKPH-GRVVNI 135 >2O23-A nrPDB Length = 265 Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 62/262 (23%), Positives = 118/262 (45%), Gaps = 28/262 (10%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 ++G VA++TGGA+G+G A + L+ G++ V+ ++ A +L N + Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN--------CV 61 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA------VLE 129 ++ +E++V + FG+++ VN G S ++ H VL+ Sbjct: 62 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 121 Query: 130 TNLTGTFYMCKAVYSSWMK---EHGGSIVNII-VPTKAGFPLAVHSG---AARAGVYNLT 182 NL GTF + + V + + GG II + A F V A++ G+ +T Sbjct: 122 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 181 Query: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEVSS 241 +A + A GIR+ +APG ++ + + +F ++P R+G P E + Sbjct: 182 LPIARDLAPIGIRVMTIAPG-LFGTPLLTSLPEKVCNFLA---SQVPFPSRLGDPAEYAH 237 Query: 242 VVCFLLSPAASFITGQSVDVDG 263 +V ++ F+ G+ + +DG Sbjct: 238 LVQAIIE--NPFLNGEVIRLDG 257 >3BHI-A nrPDB Length = 276 Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 16/144 (11%) Query: 19 QVAIVTGGATGIGKAIVKELLELGS-NVVIASRKLERLKSAADELQAN-LPPTKQARVIP 76 VA+VTGG GIG AIV++L L S +VV+ +R + R ++A +LQA L P Sbjct: 5 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFH----- 59 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQF--LSPAE-HISSKGWHAVLETNLT 133 Q +I + + + L +G ++ LVNN G F P HI ++ ++TN Sbjct: 60 -QLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAE---VTMKTNFF 115 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI 157 GT +C + + + G +VN+ Sbjct: 116 GTRDVCTELLP--LIKPQGRVVNV 137 >2NTV-A nrPDB Length = 268 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 40/278 (14%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIAS-RKLERLKSAADELQANLPPTK 70 GLL+G+ +V+G T I I K E G+ +V+ +L ++ AD L P Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPL-- 59 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGK----------INFLVNNGGG--QFLSPAEH 118 I+ +++NEE + L + G+ I F+ G G QF Sbjct: 60 ------IELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYE 113 Query: 119 ISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAG 177 SKG H ++ Y A + GGSIV + PT+A P A++ Sbjct: 114 DVSKGIH------ISTYSYASLAKALLLIMNSGGSIVGMDFDPTRA-MPAYNWMTVAKSA 166 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVI--YSQTAV------ENYGSWGQSFFEGSFQKIP 229 + ++ + +A E G+R N VA G I + +A+ E G+ Q EG Q+ P Sbjct: 167 LESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAP 226 Query: 230 AK-RIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRS 266 + P V+ VC LLS TG + DGG S Sbjct: 227 IGWNMKDPTPVAKTVCALLSEWLPATTGSIIYADGGAS 264 >1FJH-A nrPDB Length = 257 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Query: 182 TKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK-RIGVPEEVS 240 + A W +G+R+N +APG ++T + G + E + +P R P E++ Sbjct: 166 VRKRAAAWGEAGVRLNTIAPGA--TETPLLQAGLQDPRYGESIAKFVPPMGRRAEPSEMA 223 Query: 241 SVVCFLLSPAASFITGQSVDVDGG 264 SV+ FL+SPAAS++ G + +DGG Sbjct: 224 SVIAFLMSPAASYVHGAQIVIDGG 247 >2DKN-A nrPDB Length = 255 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 11/92 (11%) Query: 178 VYNLTKSLALEWACSGIRINCVAPG-----VIYSQTAVENYGSWGQSFFEGSFQKIPAKR 232 V L + ++WA G+R+N VAPG ++ + A YG + F P R Sbjct: 160 VTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVA------PLGR 213 Query: 233 IGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 P EV+ + FLL P ASFI G + VDGG Sbjct: 214 GSEPREVAEAIAFLLGPQASFIHGSVLFVDGG 245 >1ENP-A nrPDB Length = 312 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 68/285 (23%), Positives = 118/285 (41%), Gaps = 36/285 (12%) Query: 13 PGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIAS---------RKLERLKSAADE 61 P L+G+ A + G A G G A+ K L G+ +++ + L R K Sbjct: 13 PIDLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSR 72 Query: 62 LQANLPPTKQARVIPIQCNIRNEEEVNNLVKST------------------LDTFGKINF 103 + + + +V P+ N E+V VK+ FG I+ Sbjct: 73 VLPDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDI 132 Query: 104 LVNN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPT 161 LV++ G + P S KG+ A + + + +F + + M G SI + + Sbjct: 133 LVHSLANGPEVSKPLLETSRKGYLAAISAS-SYSFVSLLSHFLPIMNPGGASISLTYIAS 191 Query: 162 KAGFP-LAVHSGAARAGVYNLTKSLALEWAC-SGIRINCVAPGVIYSQTAVENYGSWGQS 219 + P +A+A + + T+ LA E IR+N ++ G + S+ A + + Sbjct: 192 ERIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAA--KAIGFIDT 249 Query: 220 FFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 E S+ P ++ +EV + FL+SP AS ITG ++ VD G Sbjct: 250 MIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNG 294 >2P91-A nrPDB Length = 285 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 65/271 (23%), Positives = 121/271 (44%), Gaps = 28/271 (10%) Query: 6 KGRSYLAPGLLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLE-RLKSA 58 KG ++ GLL+G+ A++TG A GI K+ +E +L A+ KLE R++ Sbjct: 11 KGEVFM--GLLEGKRALITGVANERSIAYGIAKSFHREGAQLA--FTYATPKLEKRVREI 66 Query: 59 ADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG----GQFLS 114 A ++L ++C++ +E++ NL K + +G ++ +V++ +F Sbjct: 67 AKGFGSDLV---------VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKG 117 Query: 115 PAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGA 173 S +G+ ++ ++ + + + M+ G+IV + + P G Sbjct: 118 GVIDTSREGFKIAMDISVYSLIALTRELLP-LMEGRNGAIVTLSYYGAEKVVPHYNVMGI 176 Query: 174 ARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRI 233 A+A + + + LA + A G RIN ++ G + + A G E + + P + Sbjct: 177 AKAALESTVRYLAYDIAKHGHRINAISAGPVKTLAAYSITGF--HLLMEHTTKVNPFGKP 234 Query: 234 GVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 E+V FL S A ITG+ V VD G Sbjct: 235 ITIEDVGDTAVFLCSDWARAITGEVVHVDNG 265 >2O2S-A nrPDB Length = 315 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 74/292 (25%), Positives = 120/292 (41%), Gaps = 50/292 (17%) Query: 16 LQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIAS---------RKLERLKSAADELQA 64 L+GQ A V G A G G AI K L G+ V + + + L+ + D Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 65 NLPPTKQARVIPIQCNIRNEEEVNNLVKST-----LDTF-------------GKINFLVN 106 + + A V P+ E+V +K +D + G I+ LV+ Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH 126 Query: 107 N--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI------- 157 + G + P S KG+ A +N +F + M E GGS V + Sbjct: 127 SLANGPEVTKPLLETSRKGYLAA-SSNSAYSFVSLLQHFGPIMNE-GGSAVTLSYLAAER 184 Query: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS-GIRINCVAPGVIYSQTAVENYGSW 216 +VP G +A+A + + T++LA E G+R+N ++ G + S+ A S Sbjct: 185 VVPGYGG-----GMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSG 239 Query: 217 GQSFFEG----SFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 +SF + S+ P +R ++V FLLSP A ++G ++ VD G Sbjct: 240 EKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNG 291 >4ALL-A nrPDB Length = 277 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 69/266 (25%), Positives = 117/266 (43%), Gaps = 35/266 (13%) Query: 16 LQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L+ + ++ G A I + K L +LG+ +V RK ER + EL+ L Q Sbjct: 25 LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRK-ERSRK---ELEKLLEQLNQPE 80 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA-----------EHISSK 122 Q +++++EEV ++ F +I V N G + S A S + Sbjct: 81 AHLYQIDVQSDEEV-------INGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSRE 133 Query: 123 GWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS----GAARAGV 178 G+ +L +++ A + + GGSIV T G AV + G A+A + Sbjct: 134 GF--LLAQDISSYSLTIVAHEAKKLMPEGGSIV---ATTYLGGEFAVQNYNVMGVAKASL 188 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 K LAL+ IR+N ++ G I + +A + G + + + ++ P KR E Sbjct: 189 EANVKYLALDLGPDNIRVNAISAGPIRTLSA-KGVGGF-NTILKEIEERAPLKRNVDQVE 246 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGG 264 V +LLS +S +TG+++ VD G Sbjct: 247 VGKTAAYLLSDLSSGVTGENIHVDSG 272 >3OML-A nrPDB Length = 613 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 44/190 (23%), Positives = 86/190 (45%), Gaps = 8/190 (4%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G+VA+VTG G+G+ E G+ VV+ A + A++ + R Sbjct: 18 DGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADI-VVDEIRKAG 76 Query: 77 IQCNIRNEEEVN--NLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++ ++++ + FG+++ LVNN G S + W+ V + +L G Sbjct: 77 GEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKG 136 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFP---LAVHSGAARAGVYNLTKSLALEWAC 191 +F +A + K++ G I I+ + +G V+ AA+ G+ L ++A+E A Sbjct: 137 SFKCTQAAFPYMKKQNYGRI--IMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 192 SGIRINCVAP 201 + + N + P Sbjct: 195 NNVLCNVIVP 204 >4M89-A nrPDB Length = 261 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 72/278 (25%), Positives = 119/278 (42%), Gaps = 37/278 (13%) Query: 14 GLLQGQVAIVTGG------ATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 G LQG+ ++TG A GI KA ++ EL V+ + ER++ A EL + L Sbjct: 2 GFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVV-DKLEERVRKMAAELDSELV 60 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG--------GQFLSPAEHI 119 +C++ +++E+N + + ++ LV++ G G FL + I Sbjct: 61 ---------FRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFL---DSI 108 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGV 178 S + ++ E + + KA M+ +IV + + P G A+A Sbjct: 109 SREAFNTAHEISAYSLPALAKAA-RPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKA-- 165 Query: 179 YNLTKSLALEWAC---SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV 235 +L + AC GIR N ++ G I + A +G+ + P +R Sbjct: 166 -SLEAGIRFTAACLGKEGIRCNGISAGPIKT-LAASGIADFGKLLGHVAAHN-PLRRNVT 222 Query: 236 PEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYE 273 EEV + FLLS +S ITG+ VDGG S+ S E Sbjct: 223 IEEVGNTAAFLLSDLSSGITGEITYVDGGYSINALSTE 260 >4Q9N-A nrPDB Length = 298 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 69/291 (23%), Positives = 115/291 (39%), Gaps = 54/291 (18%) Query: 16 LQGQVAIVTG--GATGIGKAIVKELLELGSNVVIA---------SRKLERLKSAADELQA 64 L G++A + G G G I K L E G+ +++ S+ LE K A + Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 65 NLPPTKQARVIPIQCNIRNEEE------------------VNNLVKSTLDTFGKINFLVN 106 N A++ P+ + E+ V+ +V+ FG I+ LV+ Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 107 N--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAG 164 + + P S KG+ A L T+ + +F + + M +I + + Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTS-SYSFISLLSHFGPIMNAGASTISLTYLASMRA 184 Query: 165 FP-LAVHSGAARAGVYNLTKSLALEWACS-GIRINCVAPGVIYSQTA---------VENY 213 P AA+A + + TK LA E G+R+N ++ G + S+ V+ Y Sbjct: 185 VPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGFIERMVDYY 244 Query: 214 GSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 W P E+V + FL+SP AS ITG+++ VD G Sbjct: 245 QDWA-----------PLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHG 284 >3PXX-A nrPDB Length = 287 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 63/286 (22%), Positives = 114/286 (39%), Gaps = 38/286 (13%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS--RKLER----LKSAADELQANLP 67 G +Q +V +VTGGA G G++ +L E G+++++ +E L ++ D +A L Sbjct: 6 GRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLE 65 Query: 68 PTKQAR-VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP-AEHISSKGWH 125 K R + ++R+ V+ + + + FGK++ +V N G + P H+ + + Sbjct: 66 VEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAG---ICPLGAHLPVQAFA 122 Query: 126 AVLETNLTGTFYMCKAVYSSWMKEHG----GSIVNIIVPTKAGFPLAVHSGA------AR 175 + + G A GS+ +I + A+ Sbjct: 123 DAFDVDFVGVINTVHAALPYLTSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAK 182 Query: 176 AGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSF---FEG--------- 223 V + T LA + A IR N + P + T + N + F E Sbjct: 183 QLVDSYTLQLAAQLAPQSIRANVIHPTNV--NTDMLNSAPMYRQFRPDLEAPSRADALLA 240 Query: 224 --SFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 + Q +P + ++S+ VCFL S + ++TG VD G L Sbjct: 241 FPAMQAMPTPYVEA-SDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >1N5D-A nrPDB Length = 288 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 42/144 (29%), Positives = 72/144 (50%), Gaps = 16/144 (11%) Query: 19 QVAIVTGGATGIGKAIVKELL-ELGSNVVIASRKLERLKSAADELQAN-LPPTKQARVIP 76 +VA+VTG GIG AIV++L + +VV+ +R + R ++A +LQA L P Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFH----- 59 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNG--GGQFLSPAE-HISSKGWHAVLETNLT 133 Q +I + + + L +G ++ LVNN Q +P HI ++ ++TN Sbjct: 60 -QLDIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAE---LTMKTNFM 115 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI 157 GT +C + + + G +VN+ Sbjct: 116 GTRNVCTELLP--LIKPQGRVVNV 137 >5L51-A nrPDB Length = 324 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/91 (34%), Positives = 44/91 (48%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + A+VTG GIG I K+L G V++ASR +R A + L L V+ Q Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGG 109 ++ + V LV FG ++ LVNN G Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAG 106 >5KOI-A nrPDB Length = 293 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/269 (22%), Positives = 121/269 (44%), Gaps = 32/269 (11%) Query: 14 GLLQGQVAIVTGGATGIGKA--IVKELLELGSNVVIASRKL---ERLKSAADELQANLPP 68 GL+QG+ ++ G A A I K+L G+ + + +R+K A+++ ++ Sbjct: 24 GLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDF-- 81 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 V+P C++ + V+ + + +G ++FLV+ + ++ KG +A + Sbjct: 82 -----VLP--CDVEDIATVDAVFEEIEKKWGGLDFLVHA-----IGFSDKTELKGRYADV 129 Query: 129 ETNLTGTFYMCKAVYS---------SWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGV 178 T + M + YS MK+ GGSI+ + + P G A+A + Sbjct: 130 TTRENFSRTMVISAYSFTEVAQRAEKLMKD-GGSILTLTYGGSTRTIPNYNVMGVAKAAL 188 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 + + LA ++ GIR+N ++ G + + A G ++ F + P +R ++ Sbjct: 189 EAMVRYLAADYGPQGIRVNAISAGPVRT-LAGAGIGD-ARAIFSYQRRNSPLRRTVDIDD 246 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSL 267 V +LLS +S +TG+ VD G ++ Sbjct: 247 VGKSAVYLLSDLSSGVTGEIHFVDSGYNI 275 >2PTG-A nrPDB Length = 319 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 67/303 (22%), Positives = 122/303 (40%), Gaps = 53/303 (17%) Query: 13 PGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIAS---------RKLERLKSAADE 61 P L+G+ A V G A G G AI K L G+ V++ + + LE + D Sbjct: 4 PVDLRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDS 63 Query: 62 LQANLPPTKQA-------------RVIPIQCNIRNEEEV------------------NNL 90 A P +K A ++ P+ ++V + + Sbjct: 64 FYAQEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEV 123 Query: 91 VKSTLDTFGKINFLVNN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMK 148 ++ G+I+ LV++ G + P S KG+ A + ++ + + + MK Sbjct: 124 AEAVRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQH-FLPLMK 182 Query: 149 EHGGSIVNIIVPTKAGFP-LAVHSGAARAGVYNLTKSLALEWA-CSGIRINCVAPGVIYS 206 E G ++ + ++ P +A+A + + ++LA E +R+NC++ G + S Sbjct: 183 EGGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKS 242 Query: 207 QTAVENYGSWGQSFF-----EGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDV 261 + A G G F + S P ++ ++V FLLSP A +TG ++ V Sbjct: 243 RAA-SAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYV 301 Query: 262 DGG 264 D G Sbjct: 302 DNG 304 >3GRK-A nrPDB Length = 293 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 60/264 (22%), Positives = 110/264 (41%), Gaps = 29/264 (10%) Query: 14 GLLQGQVAIVTGGATG--IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 GLLQG+ ++ G A I I K E G+ + + D L+ + P + Sbjct: 27 GLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQ--------GDALKKRVEPLAE 78 Query: 72 --ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 + C++ + ++ + ++ +GK++FLV+ G S + ++ + + E Sbjct: 79 ELGAFVAGHCDVADAASIDAVFETLEKKWGKLDFLVHAIG---FSDKDELTGR-YIDTSE 134 Query: 130 TNLTGTFYMCKAVYS--------SWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYN 180 N T T M +VYS + GGSI+ + + P G A+A + Sbjct: 135 ANFTNT--MLISVYSLTAVSRRAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALEA 192 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS 240 K LA++ IR+N ++ G I + A G + + + + P +R +EV Sbjct: 193 SVKYLAVDLGPQNIRVNAISAGPIKT-LAASGIGDF-RYILKWNEYNAPLRRTVTIDEVG 250 Query: 241 SVVCFLLSPAASFITGQSVDVDGG 264 V + LS + +TG+ D G Sbjct: 251 DVGLYFLSDLSRSVTGEVHHADSG 274 >6CGE-A nrPDB Length = 328 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 34/227 (14%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP--- 76 V ++TG ++GIG + L S L LK+ Q L +A P Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKT-----QGRLWEAARALACPPGS 59 Query: 77 ---IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 +Q ++R+ + V + T G+++ LV N G L P E + +VL+ N+ Sbjct: 60 LETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 Query: 134 GTFYMCKAVYSSWMKEHGGSI-VNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 GT M +A + G + V V G P A++ + L +SLA+ Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 G+ ++ + G +++ +F E K +G PEEV Sbjct: 178 GVHLSLIECGPVHT------------AFME--------KVLGSPEEV 204 >1MG5-A nrPDB Length = 255 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 24/209 (11%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLK--SAADELQANLPPTKQA 72 L + I G GIG KELL+ N+VI L+R++ +A EL+A + P Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVI----LDRIENPAAIAELKA-INPKVTV 58 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 P + E L+K+ ++ L+N G + + N Sbjct: 59 TFYPYDVTVP-IAETTKLLKTIFAQLKTVDVLINGAG--------ILDDHQIERTIAVNY 109 Query: 133 TGTFYMCKAVYSSWMKEHGGS---IVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 TG A+ W K GG I NI + A + + V+SG +A V N T SLA Sbjct: 110 TGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGT-KAAVVNFTSSLAK 168 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSW 216 +G+ V PG I T V + SW Sbjct: 169 LAPITGVTAYTVNPG-ITRTTLVHKFNSW 196 >1A27-A nrPDB Length = 289 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 34/227 (14%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP--- 76 V ++TG ++GIG + L S L LK+ Q L +A P Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKT-----QGRLWEAARALACPPGS 58 Query: 77 ---IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 +Q ++R+ + V + T G+++ LV N G L P E + +VL+ N+ Sbjct: 59 LETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 116 Query: 134 GTFYMCKAVYSSWMKEHGGSI-VNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 GT M +A + G + V V G P A++ + L +SLA+ Sbjct: 117 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 176 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 G+ ++ + G +++ +F E K +G PEEV Sbjct: 177 GVHLSLIECGPVHT------------AFME--------KVLGSPEEV 203 >5I9N-A nrPDB Length = 276 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 64/266 (24%), Positives = 113/266 (42%), Gaps = 32/266 (12%) Query: 14 GLLQGQVAIVTGG------ATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 G L G+ ++TG A GI KA +E EL V R +R+ A E + L Sbjct: 2 GFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYV-GDRFKDRITEFAAEFGSEL- 59 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 V P C++ ++ +++ L S + ++ LV++ G +P E I+ + Sbjct: 60 ------VFP--CDVADDAQIDALFASLKTHWDSLDGLVHSIG---FAPREAIAGDFLDGL 108 Query: 128 LETN------LTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYN 180 N ++ + A + M S++ + + + P G A+A + Sbjct: 109 TRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEA 168 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 + LA+ G+R+N ++ G I + A ++++G F E P KR E+ Sbjct: 169 SVRYLAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKI-LDFVE---SNSPLKRNVTIEQ 224 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGG 264 V + FLLS AS +T + + VD G Sbjct: 225 VGNAGAFLLSDLASGVTAEVMHVDSG 250 >4J3F-A nrPDB Length = 280 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 64/268 (23%), Positives = 115/268 (42%), Gaps = 36/268 (13%) Query: 14 GLLQGQVAIVTGG------ATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 G L G+ ++TG A GI KA+ +E EL V + K ++L A Sbjct: 22 GFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYV------GQFKDRVEKLCAEFN 75 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG--------GQFLSPAEHI 119 P A V+P C++ +++E+ +L + ++ +V++ G F+ + + Sbjct: 76 P---AAVLP--CDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFI---DCV 127 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGV 178 + +G+ + + +F S MK S+V + + + P G A+A + Sbjct: 128 TREGFSIAHDISAY-SFAALAKEGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASL 186 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIGVP 236 + AL GI++N V+ G I + A + N+ + + + P K+ Sbjct: 187 EATVRYTALALGEDGIKVNAVSAGPIKTLAASGISNF----KKMLDYNAMVSPLKKNVDI 242 Query: 237 EEVSSVVCFLLSPAASFITGQSVDVDGG 264 EV + V FL S A+ ITG+ V VD G Sbjct: 243 MEVGNTVAFLCSDMATGITGEVVHVDAG 270 >3U9L-A nrPDB Length = 324 Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 26/150 (17%), Positives = 68/150 (45%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 ++ ++ ++TG ++G G+ + L G V + R + ++ E A + Sbjct: 2 VMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDL 61 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 ++ +++++ V+ + + G+I+ L++N G PAE + + + + + N+ Sbjct: 62 RTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVLS 121 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAG 164 T + +A ++ G ++ I + AG Sbjct: 122 TQRVNRAALPHMRRQKHGLLIWISSSSSAG 151 >5TF4-A nrPDB Length = 274 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 50/209 (23%), Positives = 91/209 (43%), Gaps = 18/209 (8%) Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 C++ + ++ + + +GK++FLV+ G S E +S + + + E+N T Sbjct: 68 HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIG---FSDKEELSGR-YVDISESNFMMT-- 121 Query: 138 MCKAVYS--------SWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALE 188 M +VYS + GGSI+ + + P G A+A + K LA++ Sbjct: 122 MNISVYSLTALTKRAEKLMSDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVD 181 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 IR+N ++ G I A G + + + + P +R EEV +LLS Sbjct: 182 LGPKHIRVNAISAGPI-KTLAASGIGDF-RYILKWNEYNAPLRRTVTIEEVGDSALYLLS 239 Query: 249 PAASFITGQSVDVDGGRSLY-THSYEVPD 276 + +TG+ VD G ++ + + PD Sbjct: 240 DLSRSVTGEVHHVDSGYNIIGMKAVDAPD 268 >5CFZ-A nrPDB Length = 305 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 56/269 (20%), Positives = 116/269 (43%), Gaps = 32/269 (11%) Query: 14 GLLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 G L G+ +VTG A+ GI +A+ +E EL + + ++LK +E A L Sbjct: 45 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAF-----TYQNDKLKGRVEEFAAQLG 99 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 I +QC++ + ++ + + K + V++ G +P + + +AV Sbjct: 100 SD-----IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAV 151 Query: 128 ------LETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYN 180 + +++ ++ A M G +++ + + + P G A+A + Sbjct: 152 TREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEA 211 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 + +A G+R+N ++ G I + A ++++ + P +R E+ Sbjct: 212 NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDF----RKMLAHCEAVTPIRRTVTIED 267 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSL 267 V + FL S ++ I+G+ V VDGG S+ Sbjct: 268 VGNSAAFLCSDLSAGISGEVVHVDGGFSI 296 >4JQC-A nrPDB Length = 282 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 56/269 (20%), Positives = 116/269 (43%), Gaps = 32/269 (11%) Query: 14 GLLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 G L G+ +VTG A+ GI +A+ +E EL + + ++LK +E A L Sbjct: 22 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAF-----TYQNDKLKGRVEEFAAQLG 76 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 I +QC++ + ++ + + K + V++ G +P + + +AV Sbjct: 77 SD-----IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAV 128 Query: 128 ------LETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYN 180 + +++ ++ A M G +++ + + + P G A+A + Sbjct: 129 TREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEA 188 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 + +A G+R+N ++ G I + A ++++ + P +R E+ Sbjct: 189 NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDF----RKMLAHCEAVTPIRRTVTIED 244 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSL 267 V + FL S ++ I+G+ V VDGG S+ Sbjct: 245 VGNSAAFLCSDLSAGISGEVVHVDGGFSI 273 >4ZJU-A nrPDB Length = 275 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 64/284 (22%), Positives = 113/284 (39%), Gaps = 33/284 (11%) Query: 11 LAPGLLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLERLKSAADELQA 64 + GLL G+ ++ G A+ GI +A+ +E EL + E+LK DE Sbjct: 9 MTQGLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAF-----TYPNEKLKKRVDEFAE 63 Query: 65 NLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG--------GQFLSPA 116 V P C++ + E++N + ++ +V++ G G F Sbjct: 64 QF---GSKLVFP--CDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVT 118 Query: 117 EHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARA 176 + K H + + M +A G + ++ P G A+A Sbjct: 119 DRDGFKIAHDISAYSFVA---MARAAKPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKA 175 Query: 177 GVYNLTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIG 234 + + LA GIR+N ++ G I + A ++++ + + + + P KR Sbjct: 176 SLEAGVRYLASSLGVDGIRVNAISAGPIRTLAASGIKSF----RKMLDANEKVAPLKRNV 231 Query: 235 VPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHD 278 EEV + FL SP AS ITG+ + VD G + S + D + Sbjct: 232 TIEEVGNAALFLCSPWASGITGEILYVDAGFNTVGMSQSMMDDE 275 >4OYR-A nrPDB Length = 289 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 112/276 (40%), Gaps = 40/276 (14%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIAS-RKLERLKSAADELQANLPPTK 70 GLL G+ +V+G T I I + E G+ +V+ +L ++ D L A P Sbjct: 23 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPL-- 80 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFG----------KINFLVNNGGGQ---FLSPAE 117 ++ +++NEE + +L + G I F+ G G F +P Sbjct: 81 ------LELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYA 134 Query: 118 HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAG 177 +S KG H + + M KA+ + GGSIV + P A++ Sbjct: 135 DVS-KGIHISAYSYAS----MAKALLP--IMNPGGSIVGMDFDPSRAMPAYNWMTVAKSA 187 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVI--YSQTAV------ENYGSWGQSFFEGSFQKIP 229 + ++ + +A E G+R N VA G I + +A+ E G+ Q EG Q+ P Sbjct: 188 LESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAP 247 Query: 230 AK-RIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 + V+ VC LLS TG + DGG Sbjct: 248 IGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGG 283 >3F4B-A nrPDB Length = 323 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 57/221 (25%), Positives = 98/221 (44%), Gaps = 44/221 (19%) Query: 80 NIRNE--EEVNNLVKSTLDTFGKINFLVNN--GGGQFLSPAEHISSKGWHAVLETNLTGT 135 N++N EEV NL+ + +GKI+ LV++ G + S G+ + + Sbjct: 101 NLKNYSIEEVANLI---YNKYGKISMLVHSLANGREVQKSLLDTSRDGYLDAISKSSYSL 157 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-------IVPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 +CK + +M GGS+V++ +VP G +A+A + + T+ LA Sbjct: 158 ISLCKH-FCKFMNS-GGSVVSLTYQASQKVVPGYGG-----GMSSAKAALESDTRVLAYY 210 Query: 189 WACS-GIRINCVAPGVIYSQTAV---------------------ENYGSWGQSFFEGSFQ 226 IRIN ++ G + S+ A +NY S+ + S + Sbjct: 211 LGRKYNIRINTISAGPLKSRAATAINKFNNNQKNNMNSSGETDKQNY-SFIDYAIDYSEK 269 Query: 227 KIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 P K+ + +V SV FLLS +S +TGQ++ VD G ++ Sbjct: 270 YAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIYVDNGLNI 310 >3DWF-A nrPDB Length = 276 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 45/202 (22%), Positives = 83/202 (41%), Gaps = 8/202 (3%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA 72 P +LQG+ IVTG + GIG+ I L ++G++VV+ +R K A ++ A A Sbjct: 6 PEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARS----KEALQKVVARCLELGAA 61 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 I ++ + V + G ++ L+ N H +E N Sbjct: 62 SAHYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNF 121 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 + A M+ G V V K +PL A++ + +L E+ + Sbjct: 122 HSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVN 181 Query: 193 GIRIN---CVAPGVIYSQTAVE 211 + ++ C+ G+I ++TA++ Sbjct: 182 KVNVSITLCIL-GLIDTETAIK 202 >3UCF-A nrPDB Length = 223 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 64/266 (24%), Positives = 107/266 (40%), Gaps = 69/266 (25%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V +V GG +GIG + K+L + V +ASR+ Sbjct: 8 VYVVLGGTSGIGAELAKQLESEHTIVHVASRQ-------------------------TGL 42 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI------------SSKGWHAV 127 +I +E+ V + +T G + L+ G +PA + +K W AV Sbjct: 43 DISDEKSVYHY----FETIGAFDHLIVTAGS--YAPAGKVVDVEVTQAKYAFDTKFWGAV 96 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIV--NIIVPTKAGFPLAVHSGAARAGVYNLTKSL 185 L G Y+ + GGSI + ++ K V + A A + TK L Sbjct: 97 LAAK-HGARYL----------KQGGSITLTSGMLSRKVVANTYVKA-AINAAIEATTKVL 144 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK----IPAKRIGVPEEVSS 241 A E A IR+N ++PG+ T E Y + +Q+ +P ++G +++ Sbjct: 145 AKELAP--IRVNAISPGL----TKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIA- 197 Query: 242 VVCFLLSPAASFITGQSVDVDGGRSL 267 + +L + S++TG +DVDGG L Sbjct: 198 -MAYLFAIQNSYMTGTVIDVDGGALL 222 >3K2E-A nrPDB Length = 296 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 63/279 (22%), Positives = 109/279 (39%), Gaps = 36/279 (12%) Query: 15 LLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 L++G+ ++ G A GI KA+ + G+ V + E K D L +L Sbjct: 27 LMEGKKGVIIGVANDKSLAWGIAKAVCAQ----GAEVALTYLS-ETFKKRVDPLAESLGV 81 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 + + C++ + E V+N+ K + +G ++F+V+ S + + L Sbjct: 82 K-----LTVPCDVSDAESVDNMFKVLAEEWGSLDFVVH---AVAFSDKNELKGRYVDTSL 133 Query: 129 ETNLTGTFYMCK-----AVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLT 182 LT C A + + +GGSI+ + + P G +A + Sbjct: 134 GNFLTSMHISCYSFTYIASKAEPLMTNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASV 193 Query: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQ----KIPAKRIGVPEE 238 K LA++ IR+N ++ G V S G S F P +R ++ Sbjct: 194 KYLAVDLGKQQIRVNAISAG------PVRTLASSGISDFHYILTWNKYNSPLRRNTTLDD 247 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSLY-THSYEVPD 276 V +LLS TG++V VD G + S + PD Sbjct: 248 VGGAALYLLSDLGRGTTGETVHVDCGYHVVGMKSVDAPD 286 >5LCX-A nrPDB Length = 316 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + A+VTG GIG I ++L E G V++ SR +R A +L L + R++ Q Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKEL-NVSENRLVFHQ 66 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGG 109 ++ + V + FGK++ LVNN G Sbjct: 67 LDVTDLASVAAVAVFIKSKFGKLDILVNNAG 97 >3KZV-A nrPDB Length = 254 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 49/212 (23%), Positives = 89/212 (41%), Gaps = 34/212 (16%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVI-----ASRKLERLKSAADELQANLPPTKQA 72 G+V +VTG + GIGK+IV L L + V+ + L++LK + Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGD----------- 50 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISS---KGWHAVLE 129 R + +I + + LV + + GKI+ LV N G L P ++++ W + + Sbjct: 51 RFFYVVGDITEDSVLKQLVNAAVKGHGKIDSLVANAG--VLEPVQNVNEIDVNAWKKLYD 108 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS----GAARAGVYNLTKSL 185 N + K +G N++ + + S G+++A + + +L Sbjct: 109 INFFSIVSLVGIALPELKKTNG----NVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTL 164 Query: 186 ALEWACSGIRINCVAPGVIYSQTAV---ENYG 214 A E ++ VAPG++ + V EN G Sbjct: 165 ANEE--RQVKAIAVAPGIVDTDMQVNIRENVG 194 >4HBG-A nrPDB Length = 286 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 63/277 (22%), Positives = 100/277 (36%), Gaps = 52/277 (18%) Query: 20 VAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAAD--ELQANLPPTKQARVIP 76 VAIVTG GIGKAI ++L + G S +++ S K ++A D +LQ+ L +Q I Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC-AIA 64 Query: 77 IQCN----------------IRNEEEVNNLVKSTLDTFGK---------INFLVNNGGGQ 111 I ++ + + D K +N L+N G Sbjct: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 Query: 112 FLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMK------EHGGSIVNIIVPTKAGF 165 S + ++ ++ N M MK E G PT Sbjct: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSAR---PTIVNI 181 Query: 166 PLAVHSG-----------AARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYG 214 +HSG A++A + T+ LA E IR ++PG++ ++N Sbjct: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 Query: 215 SWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 + E + I A P E++ V L S A Sbjct: 242 VEAKEMLE---RTIGASGTSAPAEIAEEVWSLYSRTA 275 >5PGZ-A nrPDB Length = 276 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/44 (40%), Positives = 30/44 (68%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLK 56 P +LQG+ IVTG + GIG+ + L ++G++VV+ +R E L+ Sbjct: 13 PEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQ 56 >4NK4-A nrPDB Length = 301 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 23/203 (11%) Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNN----GGGQFLSPAEHISSKGWHAVLETNL 132 I CN+ + ++ L + + + ++F+V++ + P + S + ++T L Sbjct: 96 IPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNF---IQTML 152 Query: 133 TGTFYMCKAVY-SSWMKEHGGSIVNI-------IVPTKAGFPLAVHSGAARAGVYNLTKS 184 F + V ++ + HGG+++ + +VP A++ + + TK Sbjct: 153 VSCFSFTEIVRRAAQLMPHGGAMITLTYGGSMRVVPNYNAM------APAKSALESSTKY 206 Query: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 LA ++ IRIN ++ G + +T S G+ S + P KR E++ + Sbjct: 207 LACDYGGMNIRINAISAGPV--RTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSAL 264 Query: 245 FLLSPAASFITGQSVDVDGGRSL 267 +LLS ++ +TG+ VD G ++ Sbjct: 265 YLLSYLSNGVTGEIHYVDCGYNI 287 >3O26-A nrPDB Length = 311 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + A+VTGG GIG I K+L G VV+ R + + A ++L+ + + + Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGG 109 I + + +K+ FGK++ LVNN G Sbjct: 73 DPIATMSSLADFIKT---HFGKLDILVNNAG 100 >2O2Y-A nrPDB Length = 349 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 53/239 (22%), Positives = 89/239 (37%), Gaps = 71/239 (29%) Query: 85 EEVNNLVKSTLDTFGKINFLVNN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAV 142 E+V NL+ +GKIN LV++ + + S KG+ L + +CK Sbjct: 113 EDVANLIHQK---YGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKY- 168 Query: 143 YSSWMKEHGGSIVNIIVPTKAGFPLAVHSG------------AARAGVYNLTKSLALEWA 190 VNI+ P + L H+ +A+A + + T+ LA Sbjct: 169 -----------FVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG 217 Query: 191 CS-GIRINCVAPGVIYSQTAV-------------------------------------EN 212 + IRIN ++ G + S+ A +N Sbjct: 218 RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN 277 Query: 213 YGSWGQSFF----EGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 S +F E S + P ++ + ++ SV FLLS + ITGQ++ VD G ++ Sbjct: 278 SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNI 336 >4NR0-A nrPDB Length = 273 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 54/268 (20%), Positives = 116/268 (43%), Gaps = 33/268 (12%) Query: 14 GLLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 G L G+ A++ G A+ GI A+ +E EL + + ++L+ +E + Sbjct: 2 GFLTGKRALIVGVASKLSIASGIAAAMHREGAELAF-----TYQNDKLRGRVEEFASGWG 56 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI-------- 119 + + C++ ++ ++ + + + ++ +V++ G +P + + Sbjct: 57 SRPE---LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVG---FAPGDQLDGDFTAVT 110 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGV 178 + +G+ + + + KA MK GS++ + + + P G A+A + Sbjct: 111 TREGFRIAHDISAYSFIALAKA-GREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASL 169 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIGVP 236 + LA G R+N V+ G I + A ++++ + + ++ P +R Sbjct: 170 EAGVRYLAGSLGAEGTRVNAVSAGPIRTLAASGIKSF----RKMLAANERQTPLRRNVTI 225 Query: 237 EEVSSVVCFLLSPAASFITGQSVDVDGG 264 EEV + FL S AS I+G+ + VDGG Sbjct: 226 EEVGNAGAFLCSDLASGISGEILYVDGG 253 >3E9N-A nrPDB Length = 245 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 59/253 (23%), Positives = 107/253 (42%), Gaps = 35/253 (13%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIA-SRKLERLKSAADELQANLPPTKQARV 74 L+ ++A+VTG G+G IVK+L ++V A R E L + A E++ V Sbjct: 3 LKKKIAVVTGATGGMGIEIVKDLSR--DHIVYALGRNPEHLAALA-EIEG---------V 50 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 PI+ +I E V L ++ LV+ + E S WHA L+ N+ Sbjct: 51 EPIESDIVKEVLEEGGVDK-LKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIV 109 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSG-----AARAGVYNLTKSLALEW 189 + + + + ++ G ++ I +G H G A++ + L + E Sbjct: 110 PAELSRQLLPA-LRAASGCVIYI----NSGAGNGPHPGNTIYAASKHALRGLADAFRKEE 164 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 A +GIR++ V+PG + S G +F + + P+E+++ + F++ Sbjct: 165 ANNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEIYIE--------PKEIANAIRFVIDA 216 Query: 250 AASFITGQSVDVD 262 T Q +VD Sbjct: 217 GE---TTQITNVD 226 >1JPH-A nrPDB Length = 388 Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 19/99 (19%) Query: 31 GKAIVKELLELGSNVV-----IASRKLERLKSAADELQANLPPTKQARVIPIQCNIR-NE 84 G ++EL + G VV +A +K LQ NL P C + +E Sbjct: 286 GHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDP----------CALYASE 335 Query: 85 EEVNNLVKSTLDTFGKINFLVNNGGGQF--LSPAEHISS 121 EE+ LVK LD FG ++ N G G + + P EH+ + Sbjct: 336 EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDP-EHVGA 373 >1B15-A nrPDB Length = 254 Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust. Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 19/138 (13%) Query: 86 EVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSS 145 E L+K D ++ L+N G + + N TG A+ Sbjct: 70 ESKKLLKKIFDQLKTVDILINGAGI--------LDDHQIERTIAINFTGLVNTTTAILDF 121 Query: 146 WMKEHGGS---IVNIIVPTKAGFPLAVHS----GAARAGVYNLTKSLALEWACSGIRINC 198 W K GG I NI T GF A+H A++A V + T SLA +G+ Sbjct: 122 WDKRKGGPGGIIANICSVT--GFN-AIHQVPVYSASKAAVVSFTNSLAKLAPITGVTAYS 178 Query: 199 VAPGVIYSQTAVENYGSW 216 + PG+ + V + SW Sbjct: 179 INPGITRTP-LVHTFNSW 195 >4LEC-A nrPDB Length = 212 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 10/71 (14%) Query: 9 SYLAPGL--LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRK--LERLKSAADELQA 64 +YL G L+G+ A+ G TG+ IV LL G++V I RK LE LKS +QA Sbjct: 49 TYLEMGAVELRGRSAVELGAGTGL-VGIVAALL--GAHVTITDRKVALEFLKS---NVQA 102 Query: 65 NLPPTKQARVI 75 NLPP Q + + Sbjct: 103 NLPPHIQTKTV 113 >1BXK-A nrPDB Length = 355 Score = 32.3 bits (72), Expect = 0.29, Method: Compositional matrix adjust. Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 17/127 (13%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 ++TGGA IG A+V+ ++ S+ V+ KL + A L + P + R + +I Sbjct: 5 LITGGAGFIGSALVRYIINETSDAVVVVDKL----TYAGNLMSLAPVAQSERFAFEKVDI 60 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI--SSKGWHAVLETNLTGTFYMC 139 + E+ + T + + +++ L+ H+ S G A +ETN+ GT+ + Sbjct: 61 CDRAELARVF-----TEHQPDCVMH------LAAESHVDRSIDGPAAFIETNIVGTYTLL 109 Query: 140 KAVYSSW 146 +A + W Sbjct: 110 EAARAYW 116 >5CHL-B nrPDB Length = 193 Score = 31.2 bits (69), Expect = 0.51, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 3/60 (5%) Query: 52 LERLKSAADELQANLPPT-KQARVIP--IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNG 108 LE L + EL N K R+ P +Q IR +EE+++L+K+T+ G I LV G Sbjct: 132 LEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHLVPRG 191 >1OAA-A nrPDB Length = 259 Score = 30.8 bits (68), Expect = 0.76, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 3/54 (5%) Query: 20 VAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAADELQANLPPTK 70 V ++TG + G G+A+ +L L GS +++++R L+ +EL A P K Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLK 61 >2F6M-B nrPDB Length = 109 Score = 30.4 bits (67), Expect = 0.94, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLER--LKSAADELQANLPPTKQA 72 L +V + T K +++ L E+ S +VI +E+ LK + D+ Q K Sbjct: 8 LFHDEVPLFDNSITSKDKEVIETLSEIYS-IVITLDHVEKAYLKDSIDDTQYTNTVDKLL 66 Query: 73 RVIPIQCNIRNEEEVNNLVKS 93 + + N +N+EE+N +S Sbjct: 67 KQFKVYLNSQNKEEINKHFQS 87 >2CAZ-B nrPDB Length = 155 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLER--LKSAADELQANLPPTKQA 72 L +V + T K +++ L E+ S +VI +E+ LK + D+ Q K Sbjct: 25 LFHDEVPLFDNSITSKDKEVIETLSEIYS-IVITLDHVEKAYLKDSIDDTQYTNTVDKLL 83 Query: 73 RVIPIQCNIRNEEEVNNLVKS 93 + + N +N+EE+N +S Sbjct: 84 KQFKVYLNSQNKEEINKHFQS 104 >5VEY-A nrPDB Length = 194 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 52 LERLKSAADELQANLP-PTKQARVIP--IQCNIRNEEEVNNLV 91 LE L + EL N K+ R+IP +Q IRN+EE+N L+ Sbjct: 144 LEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL 186 >1LU9-A nrPDB Length = 287 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 29/52 (55%) Query: 12 APGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQ 63 A G ++G+ A+V G +G L G+ VV+ RKL++ ++AAD + Sbjct: 113 AGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVN 164 >3X0V-A nrPDB Length = 541 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 1/59 (1%) Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETF 297 ++ ++ L P ++ +S GGR LYTH + HD + GA + MK TF Sbjct: 22 IAMILDDLKIPNLTYDIFESSSRTGGR-LYTHHFTDAKHDYYDIGAMRYPDIPSMKRTF 79 >1Z45-A nrPDB Length = 699 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 20/31 (64%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIAS 49 ++ +VTGGA IG V EL+E G + V+A Sbjct: 12 KIVLVTGGAGYIGSHTVVELIENGYDCVVAD 42 >2GN9-A nrPDB Length = 344 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 9/77 (11%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLEL--GSNVVIASRKLERLKSAADELQANLPPTKQ 71 +L Q ++TGG GK V+++L+ +++ SR + LK + ++ N P Sbjct: 17 NMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSR--DELKQSEMAMEFNDP---- 70 Query: 72 ARVIPIQCNIRNEEEVN 88 R+ ++R+ E +N Sbjct: 71 -RMRFFIGDVRDLERLN 86 >2A9F-A nrPDB Length = 398 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINF 103 IPI + ++ EE+ ++VK+ TFG IN Sbjct: 108 IPIVLDTKDTEEIISIVKALAPTFGGINL 136 >2F8N-K nrPDB Length = 149 Score = 28.9 bits (63), Expect = 2.8, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 52 LERLKSAADELQANLP-PTKQARVIP--IQCNIRNEEEVNNLV 91 LE L + EL N K+ R+IP +Q IRN+EE+N L+ Sbjct: 75 LEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL 117 >2XQL-A nrPDB Length = 91 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 4/53 (7%) Query: 42 GSNVVIASRKLERLKSAADELQANLP-PTKQARVIP--IQCNIRNEEEVNNLV 91 G+ V +A+ LE L + EL N K+ R+IP +Q IRN+EE+N L+ Sbjct: 32 GAPVYLAA-VLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL 83 >5GT0-C nrPDB Length = 130 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 52 LERLKSAADELQANLP-PTKQARVIP--IQCNIRNEEEVNNLV 91 LE L + EL N K+ R+IP +Q IRN+EE+N L+ Sbjct: 55 LEYLTAEILELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLL 97 >2Q1T-A nrPDB Length = 377 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 14/25 (56%), Positives = 17/25 (68%) Query: 22 IVTGGATGIGKAIVKELLELGSNVV 46 +V GGA +G +VK LLELG N V Sbjct: 36 MVVGGAGFVGSNLVKRLLELGVNQV 60 >3C8O-A nrPDB Length = 162 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 11/63 (17%) Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP------AEHISSKGWH 125 ++ I+C E N+LVK +D GK LV +GGG AE + GW Sbjct: 34 GEIVTIKCF-----EDNSLVKEQVDKDGKGKVLVVDGGGSLRRALLGDMLAEKAAKNGWE 88 Query: 126 AVL 128 ++ Sbjct: 89 GIV 91 >5Z23-C nrPDB Length = 167 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 18/25 (72%), Gaps = 2/25 (8%) Query: 69 TKQARVIP--IQCNIRNEEEVNNLV 91 K+ R+IP +Q IRN+EE+N L+ Sbjct: 77 NKKTRIIPRHLQLAIRNDEEMNKLL 101 >6DZT-C nrPDB Length = 124 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 18/25 (72%), Gaps = 2/25 (8%) Query: 69 TKQARVIP--IQCNIRNEEEVNNLV 91 K+ R+IP +Q IRN+EE+N L+ Sbjct: 73 NKKTRIIPRHLQLAIRNDEELNKLL 97 >4B4O-A nrPDB Length = 298 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Query: 22 IVTGGATG-IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 ++ GG TG IG A+ + L G V + SRK + DEL A+ P+ A V N Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAV-----N 57 Query: 81 IRNEEEVNNLVKSTLDTFGK 100 + E +N L + +TF K Sbjct: 58 LAGENILNPLRRWN-ETFQK 76 >4NFT-A nrPDB Length = 209 Score = 27.7 bits (60), Expect = 6.0, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 3/47 (6%) Query: 52 LERLKSAADELQANLPPT-KQARVIP--IQCNIRNEEEVNNLVKSTL 95 LE L + EL N K R+ P +Q IR +EE+++L+K+T+ Sbjct: 141 LEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATI 187 >3LZ1-C nrPDB Length = 119 Score = 27.7 bits (60), Expect = 6.2, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 52 LERLKSAADELQANLP-PTKQARVIP--IQCNIRNEEEVNNLV 91 LE L + EL N K+ R+IP +Q +RN+EE+N L+ Sbjct: 55 LEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLL 97 >1KEU-A nrPDB Length = 361 Score = 27.7 bits (60), Expect = 6.5, Method: Compositional matrix adjust. Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 23/130 (17%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLE---RLKSAADELQANLPPTKQARVIPIQ 78 ++TGGA IG A+V+ +++ + V+ KL L+S +D ++N + A Sbjct: 4 LITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHA------ 57 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI--SSKGWHAVLETNLTGTF 136 +I + E+ + + L+ H+ S G A +ETN+ GT+ Sbjct: 58 -DICDSAEITRIFEQ-----------YQPDAVMHLAAESHVDRSITGPAAFIETNIVGTY 105 Query: 137 YMCKAVYSSW 146 + + W Sbjct: 106 ALLEVARKYW 115 >4EJ0-A nrPDB Length = 342 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 16/88 (18%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 IVTG A IG +VK L E G +IA L R AD+ + NL + C I Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTR----ADKFK-NL----------VDCEI 60 Query: 82 RNEEEVNNLV-KSTLDTFGKINFLVNNG 108 + + V + FGK+ + + G Sbjct: 61 DDYLDKTEFVERFARGDFGKVRAVFHEG 88 >4X23-C nrPDB Length = 102 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 18/25 (72%), Gaps = 2/25 (8%) Query: 69 TKQARVIP--IQCNIRNEEEVNNLV 91 K+ R+IP +Q IRN+EE+N L+ Sbjct: 58 NKKTRIIPRHLQLAIRNDEELNKLL 82 >4J2Q-A nrPDB Length = 380 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 16/90 (17%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP----TKQARVI 75 VA+ + K +K L+E +NVV+ S AA+E Q +PP TK ++ Sbjct: 234 VAVTNSTEKTVKK--IKVLVEQVTNVVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLV 291 Query: 76 PIQCNIRN----------EEEVNNLVKSTL 95 P+ N R + E NL ST+ Sbjct: 292 PLLANNRERRGIALDGKIKHEDTNLASSTI 321 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1YXM-A nrPDB 417 e-117 2PNF-A nrPDB 284 5e-77 2C07-A nrPDB 274 3e-74 4JRO-A nrPDB 271 3e-73 2UVD-A nrPDB 269 1e-72 2HQ1-A nrPDB 267 4e-72 3EMK-A nrPDB 266 8e-72 3OSU-A nrPDB 266 1e-71 3RSH-A nrPDB 263 6e-71 3WOH-A nrPDB 263 7e-71 3FTP-A nrPDB 257 6e-69 1Q7C-A nrPDB 256 6e-69 3F9I-A nrPDB 255 2e-68 5CDY-A nrPDB 254 3e-68 3LYL-A nrPDB 254 4e-68 4BO1-A nrPDB 252 9e-68 3GRP-A nrPDB 252 1e-67 2PH3-A nrPDB 250 6e-67 4DMM-A nrPDB 248 2e-66 5ITV-A nrPDB 247 6e-66 4M8S-A nrPDB 246 7e-66 2EW8-A nrPDB 244 5e-65 4RZH-A nrPDB 244 5e-65 3O4R-A nrPDB 241 2e-64 4K6F-A nrPDB 239 1e-63 2CDH-G nrPDB 239 1e-63 2ZAT-A nrPDB 239 1e-63 4FC7-A nrPDB 239 1e-63 4NBT-A nrPDB 238 2e-63 6NRP-A nrPDB 238 2e-63 3AUT-A nrPDB 238 2e-63 3EZL-A nrPDB 237 4e-63 2NM0-A nrPDB 237 5e-63 1GEE-A nrPDB 235 1e-62 5VT6-A nrPDB 235 2e-62 5U9P-A nrPDB 235 2e-62 3OEC-A nrPDB 234 4e-62 6CI9-A nrPDB 233 8e-62 4IIN-A nrPDB 232 1e-61 5OVL-A nrPDB 232 2e-61 3VZS-A nrPDB 232 2e-61 2AE2-A nrPDB 232 2e-61 4KMS-A nrPDB 232 2e-61 4NBV-A nrPDB 231 2e-61 4CQL-A nrPDB 231 4e-61 1AE1-A nrPDB 230 4e-61 5OJG-A nrPDB 228 2e-60 5OVJ-A nrPDB 227 3e-60 4CQM-B nrPDB 226 9e-60 4IIV-A nrPDB 226 1e-59 3V2H-A nrPDB 226 1e-59 5T5Q-A nrPDB 225 1e-59 3W8F-A nrPDB 225 2e-59 1X1T-A nrPDB 224 3e-59 1GEG-A nrPDB 224 4e-59 2Q2Q-A nrPDB 222 1e-58 3UVE-A nrPDB 222 1e-58 4RZI-B nrPDB 222 2e-58 4IS3-A nrPDB 220 4e-58 1UZM-A nrPDB 220 4e-58 4DBZ-A nrPDB 220 5e-58 3WYE-A nrPDB 220 6e-58 3R3S-A nrPDB 220 8e-58 3U5T-A nrPDB 219 1e-57 3OIC-A nrPDB 219 1e-57 4Z9Y-A nrPDB 219 1e-57 3V2G-A nrPDB 219 1e-57 1NFF-A nrPDB 218 3e-57 5YSS-A nrPDB 215 2e-56 4MOW-A nrPDB 215 2e-56 1AHH-A nrPDB 214 4e-56 3RWB-A nrPDB 214 5e-56 1K2W-A nrPDB 212 2e-55 5EJ2-A nrPDB 212 2e-55 3WTC-A nrPDB 212 2e-55 2CFC-A nrPDB 211 2e-55 3UF0-A nrPDB 211 3e-55 2P91-A nrPDB 211 3e-55 3T7C-A nrPDB 210 5e-55 1W73-A nrPDB 210 6e-55 4HP8-A nrPDB 208 3e-54 4ZJU-A nrPDB 207 5e-54 2B4Q-A nrPDB 207 5e-54 1DOH-A nrPDB 207 5e-54 4E6P-A nrPDB 206 9e-54 3D3W-A nrPDB 205 2e-53 3A28-C nrPDB 205 2e-53 1O5I-A nrPDB 205 2e-53 5JY1-A nrPDB 204 4e-53 1H5Q-A nrPDB 202 1e-52 2HSD-A nrPDB 202 1e-52 5B1Y-A nrPDB 202 2e-52 3GDF-A nrPDB 201 3e-52 3OIG-A nrPDB 198 2e-51 2AG5-A nrPDB 198 2e-51 3UN1-A nrPDB 198 3e-51 4AVY-A nrPDB 197 5e-51 3U4C-A nrPDB 196 9e-51 2YW9-A nrPDB 196 1e-50 5YCX-A nrPDB 195 2e-50 1CYD-A nrPDB 195 2e-50 2FWM-X nrPDB 193 5e-50 4EGF-A nrPDB 193 6e-50 5O3Z-A nrPDB 192 2e-49 4TRR-A nrPDB 192 2e-49 1HXH-A nrPDB 190 5e-49 5TF4-A nrPDB 190 5e-49 3V8B-A nrPDB 190 9e-49 5JS6-A nrPDB 189 1e-48 5KOI-A nrPDB 188 2e-48 3GRK-A nrPDB 187 5e-48 5CFZ-A nrPDB 186 1e-47 4M89-A nrPDB 185 2e-47 4JQC-A nrPDB 185 3e-47 3K2E-A nrPDB 184 4e-47 4ALL-A nrPDB 183 5e-47 2X9N-A nrPDB 182 1e-46 4RGB-A nrPDB 182 2e-46 4CR6-A nrPDB 182 2e-46 2BGM-A nrPDB 181 3e-46 3ZV3-A nrPDB 178 3e-45 2QHX-A nrPDB 177 6e-45 2BFA-A nrPDB 177 8e-45 1P33-A nrPDB 175 2e-44 1BDB-A nrPDB 175 2e-44 5IZ4-A nrPDB 175 3e-44 1ENP-A nrPDB 175 3e-44 4J3F-A nrPDB 173 5e-44 2GDZ-A nrPDB 173 6e-44 5I9N-A nrPDB 173 7e-44 3RKU-A nrPDB 172 2e-43 4DA9-A nrPDB 171 3e-43 2O23-A nrPDB 170 8e-43 2NWQ-A nrPDB 170 9e-43 4GKB-A nrPDB 168 2e-42 4Q9N-A nrPDB 168 2e-42 2O2S-A nrPDB 167 4e-42 3PXX-A nrPDB 167 5e-42 1E3W-A nrPDB 167 6e-42 3OML-A nrPDB 162 2e-40 2NTV-A nrPDB 154 4e-38 4OYR-A nrPDB 152 1e-37 2PTG-A nrPDB 151 3e-37 3PPI-A nrPDB 150 6e-37 1A27-A nrPDB 149 1e-36 6CGE-A nrPDB 148 3e-36 3DWF-A nrPDB 146 8e-36 4DRY-A nrPDB 145 2e-35 4HBG-A nrPDB 143 8e-35 5ILO-A nrPDB 135 3e-32 3F4B-A nrPDB 135 3e-32 2HRB-A nrPDB 128 3e-30 5L51-A nrPDB 125 3e-29 3U9L-A nrPDB 123 7e-29 3KZV-A nrPDB 122 2e-28 1N5D-A nrPDB 117 5e-27 3UCF-A nrPDB 116 8e-27 2DKN-A nrPDB 116 1e-26 3BHI-A nrPDB 115 3e-26 5LCX-A nrPDB 106 1e-23 1FJH-A nrPDB 101 4e-22 1MG5-A nrPDB 98 6e-21 Sequences not found previously or not previously below threshold: 4NR0-A nrPDB 182 1e-46 4NK4-A nrPDB 172 2e-43 2PD3-A nrPDB 146 1e-35 5PGZ-A nrPDB 137 5e-33 3E9N-A nrPDB 119 1e-27 2O2Y-A nrPDB 118 3e-27 3O26-A nrPDB 109 1e-24 1B15-A nrPDB 103 1e-22 1SNY-A nrPDB 90 1e-18 5TQV-A nrPDB 82 4e-16 4Z3K-A nrPDB 80 9e-16 4HWK-A nrPDB 80 1e-15 1OAA-A nrPDB 79 3e-15 5WQO-A nrPDB 79 3e-15 3SLK-A nrPDB 68 4e-12 4LIS-A nrPDB 64 6e-11 2PK3-A nrPDB 57 9e-09 3ORF-A nrPDB 53 1e-07 2GN9-A nrPDB 52 3e-07 1I3M-A nrPDB 51 8e-07 1UDA-A nrPDB 51 8e-07 1Z45-A nrPDB 50 2e-06 6ACF-A nrPDB 49 3e-06 6BWL-A nrPDB 48 4e-06 3ENK-A nrPDB 47 8e-06 4G5H-A nrPDB 46 1e-05 2Q1W-A nrPDB 46 2e-05 1OOE-A nrPDB 46 2e-05 3RFT-A nrPDB 45 4e-05 1GY8-A nrPDB 45 5e-05 5N2I-A nrPDB 44 1e-04 1DIR-A nrPDB 43 1e-04 2PZM-A nrPDB 43 2e-04 1LU9-A nrPDB 42 3e-04 4R1T-A nrPDB 42 3e-04 2NNL-D nrPDB 42 4e-04 4J2O-A nrPDB 42 4e-04 3VPX-A nrPDB 41 5e-04 5B6K-A nrPDB 41 8e-04 1OC2-A nrPDB 40 0.002 3PVZ-A nrPDB 40 0.002 3SXP-A nrPDB 40 0.002 1VL0-A nrPDB 39 0.002 1GPJ-A nrPDB 39 0.002 1ZZE-A nrPDB 39 0.003 4K28-A nrPDB 38 0.004 4PVC-A nrPDB 38 0.004 6GCS-E nrPDB 38 0.004 5INT-A nrPDB 38 0.004 5K1S-A nrPDB 38 0.004 3OND-A nrPDB 38 0.005 6DEB-A nrPDB 38 0.005 2Z95-A nrPDB 38 0.005 1RKX-A nrPDB 38 0.006 3LK7-A nrPDB 38 0.007 1BXK-A nrPDB 38 0.007 4KTT-E nrPDB 37 0.008 4EUF-A nrPDB 37 0.008 2C20-A nrPDB 37 0.011 1R66-A nrPDB 37 0.012 1KEU-A nrPDB 36 0.018 3NJ4-A nrPDB 36 0.020 3ZU2-A nrPDB 36 0.023 1DB3-A nrPDB 36 0.028 4J6F-A nrPDB 35 0.033 3X2F-A nrPDB 35 0.041 3HFS-A nrPDB 35 0.043 3DMF-A nrPDB 35 0.052 6ACQ-A nrPDB 35 0.054 4B4O-A nrPDB 35 0.059 3SC6-A nrPDB 35 0.060 3RUE-A nrPDB 35 0.060 2DFV-A nrPDB 34 0.073 4KUG-A nrPDB 34 0.086 6C55-A nrPDB 34 0.094 1RPN-A nrPDB 34 0.095 2EXX-A nrPDB 34 0.099 6GBN-A nrPDB 34 0.100 3H9U-A nrPDB 34 0.10 4EJ6-A nrPDB 33 0.12 3N58-A nrPDB 33 0.12 1ZDL-A nrPDB 33 0.12 7REQ-A nrPDB 33 0.13 4J90-A nrPDB 33 0.13 5JXW-A nrPDB 33 0.13 4KDR-A nrPDB 33 0.15 4EJ0-A nrPDB 33 0.16 1JAY-A nrPDB 33 0.16 5UOG-A nrPDB 33 0.16 4KDC-A nrPDB 33 0.17 3DC2-A nrPDB 33 0.17 1O89-A nrPDB 33 0.17 5TC4-A nrPDB 33 0.21 3HZZ-A nrPDB 33 0.22 5UZH-A nrPDB 33 0.23 5F5N-A nrPDB 33 0.24 3BIC-A nrPDB 33 0.25 2WEK-A nrPDB 33 0.25 3EDC-A nrPDB 32 0.27 6G2J-P nrPDB 32 0.29 2GAS-A nrPDB 32 0.30 3GFB-A nrPDB 32 0.31 1WVG-A nrPDB 32 0.31 1BW9-B nrPDB 32 0.33 3DFZ-A nrPDB 32 0.34 3CT4-A nrPDB 32 0.34 2HK7-A nrPDB 32 0.34 3H0K-A nrPDB 32 0.36 6BII-A nrPDB 31 0.46 5GUP-L nrPDB 31 0.55 4WPG-A nrPDB 31 0.56 4A10-A nrPDB 31 0.60 4BKP-A nrPDB 31 0.63 1F14-A nrPDB 31 0.70 4LSW-A nrPDB 31 0.71 2ZJ8-A nrPDB 31 0.72 4OFX-A nrPDB 31 0.73 3S8M-A nrPDB 31 0.73 2OWO-A nrPDB 31 0.74 4G2N-A nrPDB 31 0.78 3D64-A nrPDB 31 0.78 2C54-A nrPDB 31 0.78 3HDH-A nrPDB 31 0.80 5ENV-A nrPDB 31 0.83 2GGS-A nrPDB 31 0.87 4HTF-A nrPDB 31 0.89 4LEC-A nrPDB 30 1.0 3ORR-A nrPDB 30 1.0 3DQQ-A nrPDB 30 1.0 4PZE-A nrPDB 30 1.1 3G1U-A nrPDB 30 1.1 5YWN-A nrPDB 30 1.1 4WOK-A nrPDB 30 1.1 4DGK-A nrPDB 30 1.1 3PEF-A nrPDB 30 1.1 4B4V-A nrPDB 30 1.1 1C0L-A nrPDB 30 1.2 5M65-A nrPDB 30 1.2 3L07-A nrPDB 30 1.2 3R9I-A nrPDB 30 1.3 2EER-A nrPDB 30 1.3 2VN8-A nrPDB 30 1.4 4E0B-A nrPDB 30 1.4 5EGS-A nrPDB 30 1.4 3FBG-A nrPDB 30 1.6 3TLM-A nrPDB 30 1.6 1U3W-A nrPDB 30 1.6 1YXY-A nrPDB 30 1.7 6H5E-B nrPDB 30 1.7 2BIS-A nrPDB 30 1.8 5LV5-A nrPDB 30 1.9 1YB5-A nrPDB 30 1.9 3IP1-A nrPDB 30 2.0 3TQH-A nrPDB 30 2.0 6DKH-A nrPDB 30 2.0 5GXF-A nrPDB 30 2.0 5MH6-A nrPDB 30 2.1 4B3J-A nrPDB 29 2.1 2WWR-A nrPDB 29 2.2 3QWB-A nrPDB 29 2.3 1VIM-A nrPDB 29 2.6 4GBJ-A nrPDB 29 2.8 3HG7-A nrPDB 29 2.9 6GPK-A nrPDB 29 3.0 4UUP-A nrPDB 29 3.1 3ABT-A nrPDB 29 3.2 5Y2D-A nrPDB 29 3.4 4TSK-A nrPDB 29 3.4 3WR5-A nrPDB 29 3.5 5C1C-A nrPDB 29 3.6 4KMI-A nrPDB 28 3.7 4GGP-A nrPDB 28 3.7 2D0I-A nrPDB 28 4.0 5U9C-A nrPDB 28 4.1 5L3D-A nrPDB 28 4.1 6BMQ-A nrPDB 28 4.3 4A5O-A nrPDB 28 4.3 4XRR-A nrPDB 28 4.4 5NUE-A nrPDB 28 4.4 3HQ1-A nrPDB 28 4.5 1H5Y-A nrPDB 28 4.6 5O2A-B nrPDB 28 4.7 5OHX-A nrPDB 28 4.7 1JPH-A nrPDB 28 4.7 3UOG-A nrPDB 28 4.8 1ZCJ-A nrPDB 28 5.2 3VR3-A nrPDB 28 5.3 4Y4M-A nrPDB 28 5.3 5OCM-A nrPDB 28 5.4 1HYE-A nrPDB 28 5.4 1PGJ-A nrPDB 28 5.6 2IVE-A nrPDB 28 5.6 2DQ4-A nrPDB 28 5.9 1QYC-A nrPDB 28 5.9 5YBH-A nrPDB 28 5.9 1MLD-A nrPDB 28 5.9 1NHQ-A nrPDB 28 6.0 4W5U-B nrPDB 28 6.3 4QPN-A nrPDB 28 6.4 2RIR-A nrPDB 28 6.5 4A26-A nrPDB 28 6.6 3ZWA-A nrPDB 28 6.6 2X86-A nrPDB 28 6.6 5B1I-A nrPDB 28 6.6 5ZF1-A nrPDB 28 6.7 1HRD-A nrPDB 28 6.9 4I1I-A nrPDB 28 7.2 2Q4B-A nrPDB 28 7.3 1F3L-A nrPDB 28 7.5 4WLE-A nrPDB 28 7.6 1UN9-A nrPDB 27 8.7 4J0E-A nrPDB 27 8.7 3K30-A nrPDB 27 8.7 1HE4-A nrPDB 27 8.8 1IE3-A nrPDB 27 8.9 5A3V-A nrPDB 27 9.0 2Z0M-A nrPDB 27 9.3 2ZJ1-A nrPDB 27 9.8 >1YXM-A nrPDB Length = 303 Score = 417 bits (1073), Expect = e-117, Method: Composition-based stats. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD Sbjct: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS Sbjct: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 Query: 121 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN 180 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN Sbjct: 121 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN 180 Query: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS 240 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS Sbjct: 181 LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS 240 Query: 241 SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK 300 SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK Sbjct: 241 SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK 300 Query: 301 AKL 303 AKL Sbjct: 301 AKL 303 >2PNF-A nrPDB Length = 248 Score = 284 bits (726), Expect = 5e-77, Method: Composition-based stats. Identities = 89/251 (35%), Positives = 128/251 (50%), Gaps = 9/251 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+V++VTG GIG+AI ++L GS V+I ER K+ A+E+ + Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIA----NKYGVKAH 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ N+ +EE +N + + I+ LVNN G +S W VL+ NLTGT Sbjct: 61 GVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGT 120 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + + +K+ G IVNI V G V+ +AG+ TKSLA E A + Sbjct: 121 FLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNV 180 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + Q + E +IP R G PEEV++VV FL S AS+I Sbjct: 181 LVNAVAPGFIETDMTAVLSEEIKQKYKE----QIPLGRFGSPEEVANVVLFLCSELASYI 236 Query: 255 TGQSVDVDGGR 265 TG+ + V+GG Sbjct: 237 TGEVIHVNGGM 247 >2C07-A nrPDB Length = 285 Score = 274 bits (702), Expect = 3e-74, Method: Composition-based stats. Identities = 79/267 (29%), Positives = 127/267 (47%), Gaps = 12/267 (4%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 + S K +Y G + +VA+VTG GIG+ I K L + S+V+ SR + S D Sbjct: 29 LLSENKKENYYYCG--ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVD 86 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 E+++ + ++ +EE++ ++ L ++ LVNN G + + Sbjct: 87 EIKSFGYESSG-----YAGDVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMK 141 Query: 121 SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVY 179 + W VL TNL FY+ + + + G I+NI + G + +++AGV Sbjct: 142 NDEWEDVLRTNLNSLFYITQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVI 201 Query: 180 NLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 TKSLA E A I +N +APG I S + + IPA R+G PEEV Sbjct: 202 GFTKSLAKELASRNITVNAIAPGFISSDMT----DKISEQIKKNIISNIPAGRMGTPEEV 257 Query: 240 SSVVCFLLSPAASFITGQSVDVDGGRS 266 +++ CFL S + +I G+ +DGG S Sbjct: 258 ANLACFLSSDKSGYINGRVFVIDGGLS 284 >4JRO-A nrPDB Length = 271 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 85/253 (33%), Positives = 126/253 (49%), Gaps = 9/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+VA+VTGG+ GIG+ I L + G+N+ A E A L V Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPE----AAEETAKLVAEHGVEVE 82 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ N+ E+V+ K ++ FG+++ LVNN G + + W V+ NL GT Sbjct: 83 AMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGT 142 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F KAV + MK+ G I+N+ V G + A++AGV LTK+ A E A GI Sbjct: 143 FLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGI 202 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + + E +IP G E++++ V FL S A+ +I Sbjct: 203 NVNAVAPGFITTDMT----DKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYI 258 Query: 255 TGQSVDVDGGRSL 267 TGQ++ VDGG + Sbjct: 259 TGQTLSVDGGMVM 271 >2UVD-A nrPDB Length = 246 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 86/255 (33%), Positives = 138/255 (54%), Gaps = 11/255 (4%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASR-KLERLKSAADELQANLPPTKQAR 73 +L+G+VA+VTG + GIG+AI +L + G+NVV+ ++ DE++ + Sbjct: 1 MLKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKL-----GSD 55 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 I ++ ++ N E+V N+VK T+D FG+++ LVNN G + + + W V+ TNL Sbjct: 56 AIAVRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLK 115 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 G F KAV M++ G IVNI V G P + AA+AGV LTK+ A E A Sbjct: 116 GVFLCTKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASR 175 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 I +N +APG I + ++ + IPA + G +++++ V F S + Sbjct: 176 NITVNAIAPGFIATDMT----DVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSK 231 Query: 253 FITGQSVDVDGGRSL 267 +ITGQ+++VDGG + Sbjct: 232 YITGQTLNVDGGMVM 246 >2HQ1-A nrPDB Length = 247 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 92/254 (36%), Positives = 139/254 (54%), Gaps = 11/254 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLER-LKSAADELQANLPPTKQARV 74 L+G+ AIVTG + G+GKAI +L +G+N+V+ L + A+E +A V Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKA-----AGINV 57 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + + +++N E+V N+VK+ +D FG+I+ LVNN G + +S K W VL TNL Sbjct: 58 VVAKGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKS 117 Query: 135 TFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 + KAV +K+ G I+NI + G + A++AG+ TKS+A E+A G Sbjct: 118 AYLCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKG 177 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I N VAPG+I + E IP KR G PEEV++VV FL S +++ Sbjct: 178 IYCNAVAPGIIKTDMT----DVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 254 ITGQSVDVDGGRSL 267 ITGQ +++DGG + Sbjct: 234 ITGQVINIDGGLVM 247 >3EMK-A nrPDB Length = 246 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 79/254 (31%), Positives = 127/254 (50%), Gaps = 13/254 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG G+G+AI + L G+ V + + E+LK A EL R+ Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGE--------RIF 56 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 N+ + E V L + + G ++ LVNN G +S + W AVL NLT Sbjct: 57 VFPANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSV 116 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + + + M+ G I+NI + G P + A++AG+ +KSLA E A + Sbjct: 117 FNLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNV 176 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +NC+APG I S G + + IP KR+GV ++++ V +L S A+++ Sbjct: 177 TVNCIAPGFIESAMT----GKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYV 232 Query: 255 TGQSVDVDGGRSLY 268 TGQ++ V+GG ++ Sbjct: 233 TGQTLHVNGGMAMI 246 >3OSU-A nrPDB Length = 246 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 127/251 (50%), Gaps = 11/251 (4%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASR-KLERLKSAADELQANLPPTKQARVIPI 77 + A+VTG + GIG++I +L E G NV + E+ ++ +E++A K I Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKA-----KGVDSFAI 59 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 Q N+ + +EV ++K + FG ++ LVNN G + + + W V++TNL G F Sbjct: 60 QANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFN 119 Query: 138 MCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 + +++ G+I+N+ V G P + A +AGV LTKS A E A GI + Sbjct: 120 CIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITV 179 Query: 197 NCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITG 256 N VAPG I S + E +IP R G ++++ V FL S A +ITG Sbjct: 180 NAVAPGFIVSDMT----DALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITG 235 Query: 257 QSVDVDGGRSL 267 Q++ V+GG + Sbjct: 236 QTIHVNGGMYM 246 >3RSH-A nrPDB Length = 251 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 86/254 (33%), Positives = 134/254 (52%), Gaps = 13/254 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+VA+VTG + GIGKAI + L E G+ V+ + ++ +D L N Sbjct: 10 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK-------- 61 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ N E + ++K+ D FG ++ LVNN G + + + W ++ETNLT Sbjct: 62 GMALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSI 121 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + KAV MK+ G I+N+ V G + AA+AGV TKS+A E A G+ Sbjct: 122 FRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGV 181 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + + + ++PA R+G P E++S V FL SP A++I Sbjct: 182 TVNTVAPGFIETDMT----KALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYI 237 Query: 255 TGQSVDVDGGRSLY 268 TG+++ V+GG + Sbjct: 238 TGETLHVNGGMYMI 251 >3WOH-A nrPDB Length = 251 Score = 263 bits (672), Expect = 7e-71, Method: Composition-based stats. Identities = 88/260 (33%), Positives = 133/260 (51%), Gaps = 11/260 (4%) Query: 9 SYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 S PG L G+VA+VTGG+ G+G+A+ L G+ V I + S+A E Q + Sbjct: 2 SMTGPGALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDD---SSAKETQGEIER 58 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 +C++ + E+V VK+ G ++ LVNN G A I + + AV+ Sbjct: 59 L-GGTARSYRCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVM 117 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 TNL G F KA Y ++++ GSI+NI V G + +A+AG+ LTKS+A Sbjct: 118 NTNLKGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAK 177 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E A +R N VAPG+I + + + +P +R G P+EV+ +V FL Sbjct: 178 ELAERNVRCNAVAPGLIATDMTQDLVDDSKR------LDPVPMRRFGRPDEVAGLVAFLA 231 Query: 248 SPAASFITGQSVDVDGGRSL 267 +S+ITGQ V VDGG ++ Sbjct: 232 GDESSYITGQVVCVDGGMAM 251 >3FTP-A nrPDB Length = 270 Score = 257 bits (656), Expect = 6e-69, Method: Composition-based stats. Identities = 93/253 (36%), Positives = 128/253 (50%), Gaps = 10/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L QVAIVTG + GIG+AI EL G+ V+ + + + + A Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGA--- 82 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 N+ + V+ LV+STL FG +N LVNN G A + W AV++TNL Sbjct: 83 --VLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAV 140 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + +AV MK GG IVNI V AG P V+ AA+AGV +T++LA E GI Sbjct: 141 FRLSRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGI 200 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +NCVAPG I + Q +IP R+G PE+++ V FL SP A +I Sbjct: 201 TVNCVAPGFIDTDMT----KGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYI 256 Query: 255 TGQSVDVDGGRSL 267 TG ++ V+GG + Sbjct: 257 TGTTLHVNGGMFM 269 >1Q7C-A nrPDB Length = 244 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 132/254 (51%), Gaps = 13/254 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 +G++A+VTG + GIG+AI + L G+ V+ + ++ +D L AN Sbjct: 3 FEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGK-------- 54 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ + + ++++ FG+++ LVNN G + + + W+ ++ETNL+ Sbjct: 55 GLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSV 114 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + KAV + MK+ G I+ I V G + AA+AG+ +KSLA E A GI Sbjct: 115 FRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGI 174 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I + + G ++PA R+G +E+++ V FL S A++I Sbjct: 175 TVNVVAPGFIETDMT----RALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYI 230 Query: 255 TGQSVDVDGGRSLY 268 TG+++ V+GG + Sbjct: 231 TGETLHVNGGMYMV 244 >3F9I-A nrPDB Length = 249 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 85/254 (33%), Positives = 134/254 (52%), Gaps = 17/254 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ +++TG ++GIG AI + L +LGS V+I+ E+LKS + L+ N Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIE------ 65 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 CN+ N+EE +NL+ T + ++ LV N G + A + + + V++ NL Sbjct: 66 --VCNLANKEECSNLISKTSN----LDILVCNAGITSDTLAIRMKDQDFDKVIDINLKAN 119 Query: 136 FYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + + +++ G I+NI + AG P + A++AG+ +TKSL+ E A GI Sbjct: 120 FILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGI 179 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N VAPG I S + E QKIP G+PE+V+ V FL S AS+I Sbjct: 180 TVNAVAPGFIKSDMT----DKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYI 235 Query: 255 TGQSVDVDGGRSLY 268 TGQ++ V+GG + Sbjct: 236 TGQTLHVNGGMLMV 249 >5CDY-A nrPDB Length = 244 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 132/255 (51%), Gaps = 13/255 (5%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 +G++A+VTG + GIG+AI + L+E G+ V+ + + ++ + L N Sbjct: 2 SFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGK------- 54 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + N+ + ++ ++ + FG+++ LVNN G + + W +++TNLT Sbjct: 55 -GLMLNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTS 113 Query: 135 TFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + KAV + MK+ G I+ I V G V+ AA+AGV +KSLA E A G Sbjct: 114 VFRLSKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRG 173 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N VAPG I + + G ++PA R+G +E++S V FL S AS+ Sbjct: 174 ITVNVVAPGFIETDMT----RTLTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASY 229 Query: 254 ITGQSVDVDGGRSLY 268 I+G+++ V+GG + Sbjct: 230 ISGETLHVNGGMYMI 244 >3LYL-A nrPDB Length = 247 Score = 254 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 81/254 (31%), Positives = 118/254 (46%), Gaps = 10/254 (3%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L +VA+VTG + GIG + L G+ VV + A+ E N K + Sbjct: 2 SLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQ-----ASAEKFENSMKEKGFKA 56 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + NI + E + N I+ LVNN G + +S W +V+ TNL+ Sbjct: 57 RGLVLNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSS 116 Query: 135 TFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F M K MK+ G I++I V AG P + AA+AGV +KSLA E A Sbjct: 117 IFRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRN 176 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N VAPG I + KIP+ +IG P+++++ V FL S A + Sbjct: 177 ITVNVVAPGFIATDMT----DKLTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKY 232 Query: 254 ITGQSVDVDGGRSL 267 ITGQ++ V+GG + Sbjct: 233 ITGQTLHVNGGMYM 246 >4BO1-A nrPDB Length = 269 Score = 252 bits (645), Expect = 9e-68, Method: Composition-based stats. Identities = 80/259 (30%), Positives = 124/259 (47%), Gaps = 10/259 (3%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 Y LQG+VA+VTG + GIG+AI EL LG+ V+ + + A+ L+AN Sbjct: 19 YFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEG 78 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 + ++ ++E V ++ G+ +VNN G + + W V+ Sbjct: 79 AG-----LVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVN 133 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 TNL + + KAV K G I+NI V G + AA+AG+ T++LA E Sbjct: 134 TNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALARE 193 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 I +N VAPG I + E ++ E +IP R+G EE++ VV FL S Sbjct: 194 VGSRAITVNAVAPGFIDTDMTRE----LPEAQREALLGQIPLGRLGQAEEIAKVVGFLAS 249 Query: 249 PAASFITGQSVDVDGGRSL 267 A+++TG +V V+GG + Sbjct: 250 DGAAYVTGATVPVNGGMYM 268 >3GRP-A nrPDB Length = 266 Score = 252 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 75/261 (28%), Positives = 122/261 (46%), Gaps = 16/261 (6%) Query: 12 APGL---LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 PG L G+ A+VTG GIG+AI + G+ V + + ++LK A +L + Sbjct: 18 GPGSMFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKD--- 74 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 V N+ + + + L + I+ LVNN G + + W VL Sbjct: 75 -----VFVFSANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVL 129 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 NLT + + + S M+ G I+NI + G P + AA+AG+ +K+LA Sbjct: 130 AVNLTAASTLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQ 189 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E A I +NC+APG I S + E IP KR+G+ EE++ +L Sbjct: 190 EIASRNITVNCIAPGFIKSAMT----DKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLA 245 Query: 248 SPAASFITGQSVDVDGGRSLY 268 S A+++TGQ++ ++GG ++ Sbjct: 246 SDEAAYLTGQTLHINGGMAMI 266 >2PH3-A nrPDB Length = 245 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 80/249 (32%), Positives = 116/249 (46%), Gaps = 8/249 (3%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + A++TG + GIG+AI L E G + I + V + Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEV---AEEARRRGSPLVAVLG 58 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 N+ E LV + G ++ LVNN G + + + W AVLE NL+ F Sbjct: 59 ANLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRT 118 Query: 139 CKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 + MK G IVNI V G P + A++AG+ T+++A E+A GI +N Sbjct: 119 TREAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVN 178 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 VAPG I ++ Q E ++IPA R G PEEV+ V FL+S A +ITGQ Sbjct: 179 AVAPGFIETEMTER----LPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQ 234 Query: 258 SVDVDGGRS 266 ++ VDGG + Sbjct: 235 TLCVDGGLT 243 >4DMM-A nrPDB Length = 269 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 81/261 (31%), Positives = 125/261 (47%), Gaps = 13/261 (4%) Query: 9 SYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 S++ L ++A+VTG + GIG+AI EL G+ V + Sbjct: 19 SHMTALPLTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEV----VAAIA 74 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 ++ ++ E EV L + ++ +G+++ LVNN G + + W +VL Sbjct: 75 AAGGEAFAVKADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVL 134 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 + NL G F +A +K+ G I+NI V + G P + AA+AGV LTK++A Sbjct: 135 DLNLGGVFLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAK 194 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E A GI +N VAPG I + E E + IP R G EV+ VV FL Sbjct: 195 ELASRGITVNAVAPGFIATDMTSELAA-------EKLLEVIPLGRYGEAAEVAGVVRFLA 247 Query: 248 SP-AASFITGQSVDVDGGRSL 267 + AA++ITGQ +++DGG + Sbjct: 248 ADPAAAYITGQVINIDGGLVM 268 >5ITV-A nrPDB Length = 255 Score = 247 bits (630), Expect = 6e-66, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 135/256 (52%), Gaps = 12/256 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L + ++TGGA+GIG A V+ L +NVV+A + ++ + R+ Sbjct: 5 LTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRK-------ENNDRLH 57 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +Q +I +E + V+S + TFG ++ L+NN G + ++P + W+ VL+ NLTG Sbjct: 58 FVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGM 117 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F M K + G+I+N V +P A++ GV LTKS+A+++A I Sbjct: 118 FLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQI 177 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK----IPAKRIGVPEEVSSVVCFLLSPA 250 R+NCV PG+I + +++ + E ++ P R+G PEE+++V+ FL S Sbjct: 178 RVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDL 237 Query: 251 ASFITGQSVDVDGGRS 266 +S++TG ++ DGG + Sbjct: 238 SSYMTGSAITADGGYT 253 >4M8S-A nrPDB Length = 248 Score = 246 bits (629), Expect = 7e-66, Method: Composition-based stats. Identities = 77/253 (30%), Positives = 117/253 (46%), Gaps = 12/253 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G++A+VTG + GIG AI L G+ V+ + + ++ L + Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGR----- 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 N E V NL+ TFGK++ LVNN G + + + W +++ NL Sbjct: 61 --VLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSV 118 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F KAV MK+ G I+NI V G + AA+AG+ +KS+A E GI Sbjct: 119 FRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGI 178 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +NCVAPG I + Q+F + R G ++++ V FL S A +I Sbjct: 179 TVNCVAPGFIDTDMTRALPEETRQTF----TAQTALGRFGDAQDIADAVLFLASDQAKYI 234 Query: 255 TGQSVDVDGGRSL 267 TGQ++ V+GG + Sbjct: 235 TGQTLHVNGGMLM 247 >2EW8-A nrPDB Length = 249 Score = 244 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 118/252 (46%), Gaps = 10/252 (3%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+ ++A++TGGA GIG+AI + G+++ IA AA RV Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAA-------IRNLGRRV 56 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++C++ +V K + TFG+ + LVNN G L P + ++ + W E N+ Sbjct: 57 LTVKCDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDS 116 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F M KA + G I+N+ T H + +A T++LA + G Sbjct: 117 GFLMAKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDG 176 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 I +N +AP ++ + T + S Q IP R+ VP +++ FL S ASF Sbjct: 177 ITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASF 234 Query: 254 ITGQSVDVDGGR 265 ITGQ++ VDGG Sbjct: 235 ITGQTLAVDGGM 246 >4RZH-A nrPDB Length = 247 Score = 244 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 96/255 (37%), Positives = 135/255 (52%), Gaps = 13/255 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L QVA+VTG + GIGKA L G VV+ + +AAD + A + I Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVV---NYAQSSTAADAVVAEIIA-NGGEAI 59 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +Q N+ N +EV+ L+K+TLD F +I+ LVNN G + + + W AV++ NLTG Sbjct: 60 AVQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGV 119 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F KAV +K+ G I+NI V G P + AA+AGV TK++A E A G+ Sbjct: 120 FLCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGV 179 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP-AASF 253 +N VAPG I + E Q IP R G PEEV+ + FL + AA++ Sbjct: 180 TVNAVAPGFIATDMTENLNA-------EPILQFIPLARYGQPEEVAGTIRFLATDPAAAY 232 Query: 254 ITGQSVDVDGGRSLY 268 ITGQ+ +VDGG ++ Sbjct: 233 ITGQTFNVDGGMVMF 247 >3O4R-A nrPDB Length = 261 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 9/251 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L +VA+VT GIG AI + L + G++VV++SRK + + A LQ V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGE-----GLSVT 67 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ-FLSPAEHISSKGWHAVLETNLTG 134 C++ E+ LV + + G I+ LV+N F ++ + W L+ N+ Sbjct: 68 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 127 Query: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 M KAV K GGS+V + + + P ++ + LTK+LA+E A Sbjct: 128 PALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRN 187 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+NC+APG+I + + + E + + +R+G PE+ + +V FL S AS+ Sbjct: 188 IRVNCLAPGLIKT--SFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASY 245 Query: 254 ITGQSVDVDGG 264 ITG++V V GG Sbjct: 246 ITGETVVVGGG 256 >4K6F-A nrPDB Length = 255 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 123/255 (48%), Gaps = 10/255 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + ++A+VTGG G+G+A+ L + G VV+ + AD + Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPN---NTGADRWLTEMHAA-GREFH 64 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ + + ++ + G ++ LVNN G + W AV+ TNL Sbjct: 65 AYPVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSV 124 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F M K V ++ G IVNI V G + AA+AG++ TKSLALE A G+ Sbjct: 125 FNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGV 184 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFE-GSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 +N V+PG + ++ + Q + +IPA R+G PEEV+++V +L S A F Sbjct: 185 TVNTVSPGYLATKMVT----AIPQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGF 240 Query: 254 ITGQSVDVDGGRSLY 268 +TG ++ ++GG+ ++ Sbjct: 241 VTGSNIAINGGQHMH 255 >2CDH-G nrPDB Length = 244 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 83/250 (33%), Positives = 124/250 (49%), Gaps = 10/250 (4%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V +VTG + GIGKAI L + G V++ R AA+E+ + + I Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLV---NYARSAKAAEEVSKQIEA-YGGQAITFGG 58 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 ++ E +V ++K+ +D +G I+ +VNN G + + W V++ NLTG F Sbjct: 59 DVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCT 118 Query: 140 KAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 +A MK+ G I+NI V G + AA+AGV +K+ A E A I +N Sbjct: 119 QAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNV 178 Query: 199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL-SPAASFITGQ 257 V PG I S + G+ + IP R G PE V+ +V FL SPAAS+ITGQ Sbjct: 179 VCPGFIASDMTAK----LGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQ 234 Query: 258 SVDVDGGRSL 267 + +DGG ++ Sbjct: 235 AFTIDGGIAI 244 >2ZAT-A nrPDB Length = 260 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 78/251 (31%), Positives = 123/251 (49%), Gaps = 9/251 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+ +VA+VT GIG AI + L + G++VV++SRK E + LQ V Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGE-----GLSVT 66 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ-FLSPAEHISSKGWHAVLETNLTG 134 C++ E+ LV ++ G ++ LV+N F + + W +L N+ Sbjct: 67 GTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKA 126 Query: 135 TFYMCKAVYSSWMKEHGGSI-VNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 T M KAV K GGS+ + V FP ++ + LTK+LA+E A Sbjct: 127 TVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRN 186 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+NC+APG+I + ++ E + + +R+G PE+ + +V FL S AS+ Sbjct: 187 IRVNCLAPGLIKTN--FSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASY 244 Query: 254 ITGQSVDVDGG 264 ITG++V V GG Sbjct: 245 ITGETVVVGGG 255 >4FC7-A nrPDB Length = 277 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 91/261 (34%), Positives = 138/261 (52%), Gaps = 6/261 (2%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 R P LL+ +VA +TGG +GIG I + + G + VIASR L R+ +AA +L Sbjct: 17 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG--- 73 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 R +P+ ++R V V L FG+I+ L+N G FL PA +S + V Sbjct: 74 -ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 132 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLA 186 ++ + +GTF + + +Y + ++HGG IVNI G L VH+G+A+A V +T+ LA Sbjct: 133 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 192 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 +EW IR+N +APG I + G Q+ P +R+G E++ V +L Sbjct: 193 VEWGPQNIRVNSLAPGPISGTEGLRRLGG-PQASLSTKVTASPLQRLGNKTEIAHSVLYL 251 Query: 247 LSPAASFITGQSVDVDGGRSL 267 SP AS++TG + DGG L Sbjct: 252 ASPLASYVTGAVLVADGGAWL 272 >4NBT-A nrPDB Length = 240 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 120/255 (47%), Gaps = 21/255 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+VA++TGGA G+G+AI E G+ V+ V Sbjct: 4 LEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD--------------LTYSHPNVE 49 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ + V +S +D +GKI+ LVNN G + ++ W AV++ NL G Sbjct: 50 GMYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGV 109 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG- 193 F + + V GSI+NI V G + A +AGV LT + A E+A G Sbjct: 110 FNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGA 169 Query: 194 -IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 +R+N +APG I + + Q + R+G PEE++ V FL S AS Sbjct: 170 NVRVNAIAPGYIMTDI----LKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDAS 225 Query: 253 FITGQSVDVDGGRSL 267 ++TGQ+++V+GG L Sbjct: 226 YVTGQTINVNGGMRL 240 >6NRP-A nrPDB Length = 263 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 73/250 (29%), Positives = 122/250 (48%), Gaps = 15/250 (6%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRK-LERLKSAADELQANLPPTKQARVIPI 77 + +VTG + GIGKAI +L + G +V + +R + E+QA + Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQAL-----GQNSHYL 79 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 ++ + V +++ ++ G +V N G ++ + W V+ T+L G + Sbjct: 80 MFDVNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYN 139 Query: 138 MCKAVYSSWM-KEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 + K + + GG IV + V G V+ AA+AG+ TK+LALE A I Sbjct: 140 VLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKIT 199 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +NCVAPG+I ++ + E + + IP +R+G +EV+SVV FL S AS++T Sbjct: 200 VNCVAPGLIETEMVTD-------EVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVT 252 Query: 256 GQSVDVDGGR 265 Q + V+GG Sbjct: 253 RQVISVNGGL 262 >3AUT-A nrPDB Length = 269 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 80/255 (31%), Positives = 137/255 (53%), Gaps = 8/255 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+ +V ++TGG+TG+G+A+ + + VVI E A + + I Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEE----AGGQAI 68 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 +Q ++ EE+V NLV++ + FG ++ ++NN G + P+ +S W+ V++TNLTG Sbjct: 69 IVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGA 128 Query: 136 FYMCKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + +++ G+++N+ V +PL VH A++ G+ +T++LALE+A G Sbjct: 129 FLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKG 188 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+N + PG + + E + Q IP IG PEEV++V FL S AS+ Sbjct: 189 IRVNNIGPGAMNTPINAEKFADPVQR--ADVESMIPMGYIGKPEEVAAVAAFLASSQASY 246 Query: 254 ITGQSVDVDGGRSLY 268 +TG ++ DGG + Y Sbjct: 247 VTGITLFADGGMTKY 261 >3EZL-A nrPDB Length = 256 Score = 237 bits (606), Expect = 4e-63, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 113/253 (44%), Gaps = 9/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + ++A VTGG GIG +I + L + G VV + E Q L Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKAL----GFDFY 66 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ + + G+I+ LVNN G ++ + W AV++TNLT Sbjct: 67 ASEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSL 126 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F + K V ++ G I+NI V + G + A+AG++ T SLA E A G+ Sbjct: 127 FNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGV 186 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 +N V+PG I + + E IP +R+G P+E+ S+V +L S + F Sbjct: 187 TVNTVSPGYIGTDMV----KAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFS 242 Query: 255 TGQSVDVDGGRSL 267 TG ++GG + Sbjct: 243 TGADFSLNGGLHM 255 >2NM0-A nrPDB Length = 253 Score = 237 bits (605), Expect = 5e-63, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 112/258 (43%), Gaps = 21/258 (8%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 L P + +VTGG GIG AI + + G V I R E + Sbjct: 14 LVPRSHMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPE-------------- 59 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 + ++C+I + E+V K +T G + L+ N G +S + + +V+ET Sbjct: 60 --GFLAVKCDITDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVET 117 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 NLTGTF + K + ++ G +V I V G + A++AG+ +SLA E Sbjct: 118 NLTGTFRVVKRANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLAREL 177 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 I N VAPG + + ++P R PEE+++ V FL S Sbjct: 178 GSRNITFNVVAPGFVDTDMT----KVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASD 233 Query: 250 AASFITGQSVDVDGGRSL 267 AS+ITG + VDGG + Sbjct: 234 DASYITGAVIPVDGGLGM 251 >1GEE-A nrPDB Length = 261 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 80/255 (31%), Positives = 139/255 (54%), Gaps = 8/255 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+V ++TG +TG+GK++ + VV+ R E ++ E + I Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKV----GGEAI 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ ++ E +V NLV+S + FGK++ ++NN G + + +S W+ V++TNLTG Sbjct: 61 AVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGA 120 Query: 136 FYMCKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + +++ G+++N+ V K +PL VH A++ G+ +T++LALE+A G Sbjct: 121 FLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKG 180 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+N + PG I + E + Q IP IG PEE+++V +L S AS+ Sbjct: 181 IRVNNIGPGAINTPINAEKFADPEQR--ADVESMIPMGYIGEPEEIAAVAAWLASSEASY 238 Query: 254 ITGQSVDVDGGRSLY 268 +TG ++ DGG +LY Sbjct: 239 VTGITLFADGGMTLY 253 >5VT6-A nrPDB Length = 269 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 123/258 (47%), Gaps = 9/258 (3%) Query: 12 APGLLQGQ-VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 PG +Q + VA VTGG G+G AI + L + G V ++ ER + L + Sbjct: 18 GPGSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVS--HSERNDHVSTWLMHERDAGR 75 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 + + ++ + E + L FGK++ L+NN G + ++ W AV+ T Sbjct: 76 DFKAYAV--DVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRT 133 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 +L F + K + ++ G IVNI V G + +A+AG++ TK+LALE Sbjct: 134 DLDAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALET 193 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 A GI +N V+PG + + +IP R+G P+EV++++ FL S Sbjct: 194 AKRGITVNTVSPGYLATAMVEAVPQDV---LEAKILPQIPVGRLGRPDEVAALIAFLCSD 250 Query: 250 AASFITGQSVDVDGGRSL 267 A F+TG + ++GG + Sbjct: 251 DAGFVTGADLAINGGMHM 268 >5U9P-A nrPDB Length = 265 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 73/259 (28%), Positives = 117/259 (45%), Gaps = 8/259 (3%) Query: 9 SYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 L L G+ A++TG GIG + + L E G+ +VI R E+ + A + Sbjct: 11 HALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFA 70 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 A ++ +V + G I+ LVNN G Q +P + WHA++ Sbjct: 71 ADHA-----VFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALM 125 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 NL G F + +AV + G I+NI V ++ P A + V LTK + Sbjct: 126 RVNLDGVFNVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCA 185 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 +WA GI+ N +APG ++ + +F + ++ PA R G +E+ FL Sbjct: 186 DWARYGIQANGLAPGYFETE--LNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLA 243 Query: 248 SPAASFITGQSVDVDGGRS 266 S A+ F+ GQ++ VDGG + Sbjct: 244 SAASDFVNGQTLFVDGGLT 262 >3OEC-A nrPDB Length = 317 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 78/273 (28%), Positives = 128/273 (46%), Gaps = 22/273 (8%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASR-----KLERLKSAADELQA--NL 66 LQG+VA +TG A G G+ L + G+++V L+ + + +EL+ L Sbjct: 42 NRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRL 101 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA 126 + R+I Q ++R+ + +V L FG I+ LV+N G ++ + W Sbjct: 102 VEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSD 161 Query: 127 VLETNLTGTFYMCKAVYSSWMKE-HGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKS 184 +L+TNL G ++ C+AV S ++ GGS++ + G P H A++ GV L S Sbjct: 162 ILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLS 221 Query: 185 LALEWACSGIRINCVAPGVIYSQTA------------VENYGSWGQSFFEGSFQKIPAKR 232 LA E IR+N V PG + ++ A +EN + +P Sbjct: 222 LANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP- 280 Query: 233 IGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265 PE+VS+ V +L S A +I G ++ VDGG+ Sbjct: 281 WVEPEDVSNAVAWLASDEARYIHGAAIPVDGGQ 313 >6CI9-A nrPDB Length = 259 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 71/255 (27%), Positives = 118/255 (46%), Gaps = 11/255 (4%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+G+ AIVTGG+ GIG+ I + G +VVI R + L +L + +V Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGT-----RGKV 60 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 ++ ++ + E+ V T+ G ++ + N G E ++ VL N G Sbjct: 61 TAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKG 120 Query: 135 TFYMCKAVYSSWMKEHGGSIV--NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 T Y+ +A + G +V + I G+P H GA++A ++ A+E A Sbjct: 121 TVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPK 180 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 I IN V PG I + E GQ + + IPA R+G ++ + F + A+ Sbjct: 181 KITINAVLPGNIMT----EGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAA 236 Query: 253 FITGQSVDVDGGRSL 267 ++TGQ++ VDGG+ L Sbjct: 237 YVTGQTLVVDGGQVL 251 >4IIN-A nrPDB Length = 271 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 72/253 (28%), Positives = 121/253 (47%), Gaps = 9/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G+ ++TG + GIG I K L +G V I R AD L+ L K + Sbjct: 27 FTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNA---EVADALKNELEE-KGYKAA 82 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 I+ + +E + +++ + + G +++LVNN G A + ++ +H V++ NLT Sbjct: 83 VIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSA 142 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F C+ K GS+VN+ + + G + A++ G+ ++KS A E A I Sbjct: 143 FIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNI 202 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R N V PG I + + + IP R+G +EV+ V FLLS +S+I Sbjct: 203 RFNSVTPGFIETDMNA----NLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYI 258 Query: 255 TGQSVDVDGGRSL 267 TG+++ V+GG + Sbjct: 259 TGETLKVNGGLYM 271 >5OVL-A nrPDB Length = 300 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 112/250 (44%), Gaps = 21/250 (8%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + +VTGG GIG AI + L G V + R + +Q Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHR----------------GSGAPDDLFGVQ 112 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 C++ + V+ K + G + LV N G + ++ + + V+ TNLTG F Sbjct: 113 CDVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRC 172 Query: 139 CKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 + + ++ G I+ I V G + AA+AG+ + +S++ E A +G+ N Sbjct: 173 AQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTAN 232 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 VAPG I ++ + + G+ IPAKR+G EEV+ V FL S AS+I G Sbjct: 233 VVAPGYIDTEMT----RALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGA 288 Query: 258 SVDVDGGRSL 267 + VDGG + Sbjct: 289 VIPVDGGMGM 298 >3VZS-A nrPDB Length = 257 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 112/250 (44%), Gaps = 9/250 (3%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 ++A VTGG GIG AI + L + G VV + E Q L I + Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKAL----GFDFIASE 70 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 N+ + + G+++ L+NN G ++ W AV++TNLT F + Sbjct: 71 GNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNV 130 Query: 139 CKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 K V G IVNI V + G + A+AG++ T +LA E A G+ +N Sbjct: 131 TKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVN 190 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 V+PG I + + Q + IP KR+G+PEE++S+ +L S + F TG Sbjct: 191 TVSPGYIATDMV----KAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGA 246 Query: 258 SVDVDGGRSL 267 ++GG + Sbjct: 247 DFSLNGGLHM 256 >2AE2-A nrPDB Length = 260 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 77/253 (30%), Positives = 122/253 (48%), Gaps = 8/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G A+VTGG+ GIG IV+EL LG++V SR + L + +K +V Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQ-----WRSKGFKVE 61 Query: 76 PIQCNIRNEEEVNNLVKSTLDTF-GKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 C++ + E L+ + + F GK+N LVNN G A+ + + + ++ N Sbjct: 62 ASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEA 121 Query: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 +++ + G++V I V P GA + + LT+ LA EWA Sbjct: 122 AYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDN 181 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSF-FEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 IR+N V PGVI + Q + +R+G P+E++++V FL PAAS Sbjct: 182 IRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAAS 241 Query: 253 FITGQSVDVDGGR 265 ++TGQ + VDGG Sbjct: 242 YVTGQIIYVDGGL 254 >4KMS-A nrPDB Length = 249 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 82/251 (32%), Positives = 120/251 (47%), Gaps = 15/251 (5%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +AIVTGG GIGKA EL G VV AA E++ + Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVA---NFFSNYDAAKEMEEKYGIKTKCW------ 62 Query: 80 NIRNEEEVNNLVKSTLDTFGK-INFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 N+ + EE VK + F K ++ LVNN G +S + W+ V+ NL F M Sbjct: 63 NVADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNM 122 Query: 139 CKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 +V + G IVNI + +AG + AA+AG+ TK+LA E A I +N Sbjct: 123 SSSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVN 182 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 C+APG I ++ G+ + IP KR+G PEE++ V FL+ A FITG+ Sbjct: 183 CIAPGYIATEMV----GAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGE 238 Query: 258 SVDVDGGRSLY 268 ++ ++GG ++ Sbjct: 239 TISINGGHNMI 249 >4NBV-A nrPDB Length = 246 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 72/253 (28%), Positives = 120/253 (47%), Gaps = 10/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+VAI+TG A GIG A + E G+ VV+ + R++ AA A V Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAA-----ARLAATGATVS 57 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ +EV+ +V + L +++ LVNN G + ++ + AV++ NL G Sbjct: 58 AYRVDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGV 117 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F +AV ++ G I+N V G + A++ GV TK+ A E G+ Sbjct: 118 FNCAQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGV 177 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R+N V PG + ++ +G +R+ P E++S+ FL S AS++ Sbjct: 178 RVNAVCPGFVNTEILQTV----PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYV 233 Query: 255 TGQSVDVDGGRSL 267 G +++ GG SL Sbjct: 234 NGVAIEASGGMSL 246 >4CQL-A nrPDB Length = 261 Score = 231 bits (589), Expect = 4e-61, Method: Composition-based stats. Identities = 76/272 (27%), Positives = 117/272 (43%), Gaps = 16/272 (5%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 MAS + R L+ +A+VTG +GIG+A+ L G+ V + Sbjct: 1 MASQLQNR-------LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVR 53 Query: 61 ELQANLPPTKQAR--VIPIQCNIRNEEEVNNLVKSTLDTFGKI-NFLVNNGGGQFLSPAE 117 L R Q ++ L++ F + + +V+ G Sbjct: 54 LLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLL 113 Query: 118 HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEH-GGSIVNII-VPTKAGFPLAVHSGAAR 175 H+S W V+ NL GTF + +A + + GSI+NI + K G + A++ Sbjct: 114 HMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASK 173 Query: 176 AGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV 235 AGV LT++ A E GIR N V PG I + + Q + + IP +G Sbjct: 174 AGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV----PQKVVDKITEMIPMGHLGD 229 Query: 236 PEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 PE+V+ VV FL S + +ITG SV+V GG + Sbjct: 230 PEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 >1AE1-A nrPDB Length = 273 Score = 230 bits (588), Expect = 4e-61, Method: Composition-based stats. Identities = 81/256 (31%), Positives = 128/256 (50%), Gaps = 9/256 (3%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+G A+VTGG+ GIG AIV+EL LG+ V SR + L + + K V Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLE-----IWREKGLNV 72 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTF-GKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 C++ + E + L+++ F GK+N LVNN G A+ + K ++ ++ TN Sbjct: 73 EGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFE 132 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 +++ + Y G+++ + + + P A++ + +TKSLA EWA Sbjct: 133 AAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKD 192 Query: 193 GIRINCVAPGVIYSQTAVENYGSWG--QSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 IR+N VAPGVI + + + K P R G P+EVS+++ FL PA Sbjct: 193 NIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPA 252 Query: 251 ASFITGQSVDVDGGRS 266 AS+ITGQ + DGG + Sbjct: 253 ASYITGQIIWADGGFT 268 >5OJG-A nrPDB Length = 260 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 83/255 (32%), Positives = 129/255 (50%), Gaps = 7/255 (2%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA 72 +G+VAIVT GIG AI + LL+ G++VVI SR + + A + L+ Sbjct: 5 CRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLK----NKGLT 60 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ-FLSPAEHISSKGWHAVLETN 131 +V I +I + ++ LV TL FGKIN LVNN G +S + W + E N Sbjct: 61 KVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVN 120 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 + F M K V+ KE GG+I+ N P G + + LT++LA+ A Sbjct: 121 VKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLA 180 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGS-FQKIPAKRIGVPEEVSSVVCFLLSP 249 IR+N +APGVI ++ + + + E + Q+I R+GVP++ + V +L S Sbjct: 181 KDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASD 240 Query: 250 AASFITGQSVDVDGG 264 +S+ITG+ + + GG Sbjct: 241 DSSYITGEMIIIAGG 255 >5OVJ-A nrPDB Length = 256 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 112/250 (44%), Gaps = 21/250 (8%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + +VTGG GIG AI + L G V + R + +Q Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHR----------------GSGAPDDLFGVQ 68 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 C++ + V+ K + G + LV N G + ++ + + V+ TNLTG F Sbjct: 69 CDVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRC 128 Query: 139 CKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 + + ++ G I+ I V G + AA+AG+ + +S++ E A +G+ N Sbjct: 129 AQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTAN 188 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 VAPG I ++ + + G+ IPAKR+G EEV+ V FL S AS+I G Sbjct: 189 VVAPGYIDTEMT----RALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGA 244 Query: 258 SVDVDGGRSL 267 + VDGG + Sbjct: 245 VIPVDGGMGM 254 >4CQM-B nrPDB Length = 244 Score = 226 bits (577), Expect = 9e-60, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 118/252 (46%), Gaps = 18/252 (7%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 +V V GG+ GIG+A+ + + G + + +R LE K+AA +L + Sbjct: 9 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL--------GGDHLAF 60 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 C++ E +V N + G++NFLVN G ++ + L TNL G+ Sbjct: 61 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 120 Query: 138 MCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 CKA + +++ GGSIVN+ + G A++ G+ +++LA E A IR+ Sbjct: 121 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 180 Query: 197 NCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITG 256 N VAPG +++ + E + IP R G EV+ V FLL + +ITG Sbjct: 181 NVVAPGFVHTDMTKDLK-------EEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITG 231 Query: 257 QSVDVDGGRSLY 268 + VDGG L Sbjct: 232 HVLVVDGGLQLI 243 >4IIV-A nrPDB Length = 267 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 68/258 (26%), Positives = 123/258 (47%), Gaps = 12/258 (4%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 Y + + +VTG + GIG+AI ++L G N+ + + A + L A + Sbjct: 19 YFQSNAMS-RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAG--AQETLNAIVANG 75 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 R++ ++ N E+ +++ + G +V+N G + +S+ W AV+ Sbjct: 76 GNGRLLSF--DVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIH 133 Query: 130 TNLTGTFYMCKAVYSSWM-KEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 TNL + + + + GG I+ + V G V+ AA+AG+ TK+LA+ Sbjct: 134 TNLDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAI 193 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E A I +NC+APG+I + +S + + IP KR+G EEV+ + +L+ Sbjct: 194 ELAKRKITVNCIAPGLIDTGM-----IEMEESALKEAMSMIPMKRMGQAEEVAGLASYLM 248 Query: 248 SPAASFITGQSVDVDGGR 265 S A ++T Q + ++GG Sbjct: 249 SDIAGYVTRQVISINGGM 266 >3V2H-A nrPDB Length = 281 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 68/262 (25%), Positives = 120/262 (45%), Gaps = 14/262 (5%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKL-ERLKSAADELQANLPPTKQAR 73 + + A++TG +GIG AI + L + G+N+V+ + +++ DE+ Sbjct: 22 SMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAG----LSSGT 77 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 V+ ++ E+ +++ D FG + LVNN G QF+ E + W ++ NL+ Sbjct: 78 VLHHPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLS 137 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 +F+ + K+ G I+NI P AA+ G+ LTK++ALE A S Sbjct: 138 SSFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAES 197 Query: 193 GIRINCVAPGVIYSQTAVENYGSW--------GQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 G+ +N + PG + + + Q E + P K+ E+V+S+ Sbjct: 198 GVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLAL 257 Query: 245 FLLSPAASFITGQSVDVDGGRS 266 +L A+ ITG V +DGG + Sbjct: 258 YLAGDDAAQITGTHVSMDGGWT 279 >5T5Q-A nrPDB Length = 247 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 130/253 (51%), Gaps = 14/253 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + + ++TG GIG+AI + G+N+V+ E L + A L + R+ Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGS------PERIA 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 I+ + + ++ V ++ FG I+FLV + G P +S WH + NL G Sbjct: 61 TIKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGV 120 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 FY+CK + ++ SIV + + G + H GA + + ++T++L+ E A Sbjct: 121 FYLCKRALPALKED--SSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-T 177 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R+N V+PG+I + E ++ + + + P KR+G P E++SV+ FL SPAASF+ Sbjct: 178 RVNGVSPGIIETPMTSELL----KTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFV 233 Query: 255 TGQSVDVDGGRSL 267 TG+++ V+GG + Sbjct: 234 TGETIQVNGGIYM 246 >3W8F-A nrPDB Length = 260 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 69/261 (26%), Positives = 117/261 (44%), Gaps = 12/261 (4%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 +L+G+ A+VTG +GIG A+ EL + G++VVI + ++ L + Sbjct: 1 MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQP---EDIERERSTLESKFGVKA 57 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++ + + + + + G ++ LVNN G Q +P E W+A++ NL+ Sbjct: 58 YYLNADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSA 117 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F+ A K+ G I+NI AA+ GV LTK ALE A G Sbjct: 118 VFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKG 177 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQ--------SFFEGSFQKIPAKRIGVPEEVSSVVCF 245 I N + PG + + + + Q + E +K P+ + PE++ F Sbjct: 178 ITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVF 237 Query: 246 LLSPAASFITGQSVDVDGGRS 266 L S AA +TG ++ +DGG + Sbjct: 238 LSSAAADQMTGTTLSLDGGWT 258 >1X1T-A nrPDB Length = 260 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 77/261 (29%), Positives = 121/261 (46%), Gaps = 12/261 (4%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 +L+G+VA+VTG +GIG I L G+++V+ + ++++A L +V Sbjct: 1 MLKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDA---AEIEKVRAGLAAQHGVKV 57 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + ++ E V LV + + G+I+ LVNN G Q + E ++ W A+L NL+ Sbjct: 58 LYDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSA 117 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F+ A K+ G I+NI AA+ GV TK ALE A G Sbjct: 118 VFHGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQG 177 Query: 194 IRINCVAPGVIYSQ--------TAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 I N + PG + + A +N + E +K P+ + PE++ F Sbjct: 178 ITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVF 237 Query: 246 LLSPAASFITGQSVDVDGGRS 266 L S AA+ ITG +V VDGG + Sbjct: 238 LASDAAAQITGTTVSVDGGWT 258 >1GEG-A nrPDB Length = 256 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 120/256 (46%), Gaps = 14/256 (5%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA+VTG GIGKAI L++ G V IA K+ A E+ + ++ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEI-----NQAGGHAVAVK 57 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ + ++V V+ T G + +VNN G +P E I+ + V N+ G + Sbjct: 58 VDVSDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWG 117 Query: 139 CKAVYSSWMKEH-GGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 +A ++ KE GG I+N G P +++ V LT++ A + A GI + Sbjct: 118 IQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITV 177 Query: 197 NCVAPGVIYSQTAVENYGSWGQSFFE-------GSFQKIPAKRIGVPEEVSSVVCFLLSP 249 N PG++ + E ++ + ++I R+ PE+V++ V +L SP Sbjct: 178 NGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASP 237 Query: 250 AASFITGQSVDVDGGR 265 + ++TGQS+ +DGG Sbjct: 238 DSDYMTGQSLLIDGGM 253 >2Q2Q-A nrPDB Length = 255 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 68/258 (26%), Positives = 114/258 (44%), Gaps = 15/258 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ A+VTG +GIG I + L G+N+V+ + + A+ + + Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFG-DPAPALAE------IARHGVKAV 54 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ + ++ L FG ++ LVNN G Q ++P E + W ++ NL+ Sbjct: 55 HHPADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAV 114 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F+ + + G I+NI V G AA+ GV LTK + LE A S + Sbjct: 115 FHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNV 174 Query: 195 RINCVAPGVIYSQTAVE-------NYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 N + PG + + + N G Q+ + +K P+ PE + +V FL Sbjct: 175 TCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLC 234 Query: 248 SPAASFITGQSVDVDGGR 265 S A S + G + +VDGG Sbjct: 235 SEAGSQVRGAAWNVDGGW 252 >3UVE-A nrPDB Length = 286 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 66/280 (23%), Positives = 119/280 (42%), Gaps = 27/280 (9%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASR---------KLERLKSAADELQ- 63 G ++G+VA VTG A G G++ L + G++++ S ++L Sbjct: 7 GRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAE 66 Query: 64 -ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG-QFLSPAEHISS 121 A+L R++ + ++R+ + + V S ++ G+++ +V N G + S Sbjct: 67 TADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSE 126 Query: 122 KGWHAVLETNLTGTFYMCKAVYSSWMKE-HGGSIV-NIIVPTKAGFPLAVHSGAARAGVY 179 + W +++ NL G + KA + GGSI+ V +P H AA+ GV Sbjct: 127 EDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVV 186 Query: 180 NLTKSLALEWACSGIRINCVAPGVIYSQT------------AVENYGSWGQSFFEGSFQK 227 L ++ +E IR+N V P + + +EN G + F Sbjct: 187 GLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHT 246 Query: 228 IPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 +P P ++S+ V F S A +ITG ++ +D G L Sbjct: 247 LPIP-WVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >4RZI-B nrPDB Length = 240 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 78/250 (31%), Positives = 118/250 (47%), Gaps = 21/250 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+ +V +VTGG GIG AIVK L E+G+ V + + A + Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA---------------L 50 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + N+ + E + D G + +V N G + ++ W AVL NL G Sbjct: 51 GVVANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGV 110 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 Y K + GSIV I + + G + A +AGV + KSLA E A G+ Sbjct: 111 AYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGV 170 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP-AASF 253 R N VAPG I ++ + + + E ++IP +R G PEE++ V FLLSP A+S+ Sbjct: 171 RANAVAPGFIDTEMTL----AIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSY 226 Query: 254 ITGQSVDVDG 263 +TG+ + V+G Sbjct: 227 VTGEVLRVNG 236 >4IS3-A nrPDB Length = 268 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 72/255 (28%), Positives = 115/255 (45%), Gaps = 8/255 (3%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 + L+Q +V I+TGG GIG A K ++ G+ V I E + +A +L+ P Sbjct: 17 FQGMNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEE 76 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 V+ ++ + + V V +G+++ ++NN G + +S + + +++ Sbjct: 77 ---EVLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMD 133 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 N+TG F Y G I+N V G V A++A V LT L E Sbjct: 134 INVTGVFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGRE 193 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 IR+ VAPGV+ + EG + +P KR+ PEE+++V FL S Sbjct: 194 IIRKNIRVVGVAPGVVNTDMT----NGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLAS 249 Query: 249 PAASFITGQSVDVDG 263 AS IT +V VDG Sbjct: 250 DLASGITATTVSVDG 264 >1UZM-A nrPDB Length = 247 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 67/250 (26%), Positives = 114/250 (45%), Gaps = 21/250 (8%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + +VTGG GIG AI + L G V + R + ++ Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHR----------------GSGAPKGLFGVE 59 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ + + V+ + + G + LV+N G + ++ + + V+ NLTG F + Sbjct: 60 VDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRV 119 Query: 139 CKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 + S + G ++ I V G + A++AGV + +S+A E + + + N Sbjct: 120 AQRASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTAN 179 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 VAPG I + + + +G+ Q IPAKR+G P EV+ VV FL S AS+I+G Sbjct: 180 VVAPGYIDTDMT----RALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGA 235 Query: 258 SVDVDGGRSL 267 + VDGG + Sbjct: 236 VIPVDGGMGM 245 >4DBZ-A nrPDB Length = 281 Score = 220 bits (562), Expect = 5e-58, Method: Composition-based stats. Identities = 79/259 (30%), Positives = 128/259 (49%), Gaps = 15/259 (5%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA+VTG +GIG I + L + G V + +R E L++ EL+ C Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRT-----C 82 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 ++R+ E+ LV + ++ +G ++ LVNN G ++ + W V+ETNLTG F + Sbjct: 83 DVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVT 142 Query: 140 KAVYSS--WMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 K V + ++ G IVNI K G A A++ GV TK+L LE A +GI + Sbjct: 143 KQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITV 202 Query: 197 NCVAPGVIYSQTAV-------ENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 N V PG + + A + + + F+ ++P R P EV+ +V +L+ P Sbjct: 203 NAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGP 262 Query: 250 AASFITGQSVDVDGGRSLY 268 A+ +T Q+++V GG Y Sbjct: 263 GAAAVTAQALNVCGGLGNY 281 >3WYE-A nrPDB Length = 256 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 71/257 (27%), Positives = 119/257 (46%), Gaps = 16/257 (6%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA+VTG GIGKAI L++ G V IA K+ A E+ + ++ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEI-----NQAGGHAVAVK 57 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ + ++V V+ T G + +VNN G + P ++ + + N+ F+ Sbjct: 58 VDVSDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFG 117 Query: 139 CKAVYSSWMKEHGG--SIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 +A ++ KE G I + GFP+ + V LT++ A + A GI + Sbjct: 118 IQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITV 177 Query: 197 NCVAPGVIYSQTAVE--------NYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 N PG++ + + N G++F E S I R VPE+V+ +V FL S Sbjct: 178 NGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYS-SSIALGRPSVPEDVAGLVSFLAS 236 Query: 249 PAASFITGQSVDVDGGR 265 P + ++TGQS+ +DGG Sbjct: 237 PDSDYMTGQSLLIDGGM 253 >3R3S-A nrPDB Length = 294 Score = 220 bits (560), Expect = 8e-58, Method: Composition-based stats. Identities = 69/262 (26%), Positives = 123/262 (46%), Gaps = 9/262 (3%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 +SY+ G L+ + A+VTGG +GIG+A G++V I E + A +++A + Sbjct: 39 KSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAE--EEDAQQVKALIE 96 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP-AEHISSKGWHA 126 + + + ++ +E +LV + G ++ L G Q P + ++S+ + Sbjct: 97 EC-GRKAVLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQ 155 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSL 185 N+ F++ + K G SI+ + P + A +A + N ++ L Sbjct: 156 TFAVNVFALFWITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGL 213 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 A + A GIR+N VAPG I++ A++ G Q Q+ P KR G P E++ V + Sbjct: 214 AKQVAEKGIRVNIVAPGPIWT--ALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVY 271 Query: 246 LLSPAASFITGQSVDVDGGRSL 267 L S +S++T + V GG L Sbjct: 272 LASQESSYVTAEVHGVCGGEHL 293 >3U5T-A nrPDB Length = 267 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 109/256 (42%), Gaps = 10/256 (3%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 Y + +VAIVTG + GIG AI L G VVI K+AA E A Sbjct: 19 YFQSMMETNKVAIVTGASRGIGAAIAARLASDGFTVVINY----AGKAAAAEEVAGKIEA 74 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 + + Q ++ + V L + + FG ++ LVNN G L+ + V+ Sbjct: 75 AGGKALTAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIA 134 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGF-PLAVHSGAARAGVYNLTKSLALE 188 NL GTF + GG I+N+ P AA+AGV +T L+ E Sbjct: 135 VNLKGTFNTLREAAQRL--RVGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKE 192 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 I +N VAPG + +E + + P +R+G P++++ V FL Sbjct: 193 LRGRDITVNAVAPGPTATDLFLE---GKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAG 249 Query: 249 PAASFITGQSVDVDGG 264 P +++ GQ + +GG Sbjct: 250 PDGAWVNGQVLRANGG 265 >3OIC-A nrPDB Length = 258 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 7/255 (2%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 Q + A+VTG + G+GKA L E G N+VI R K AA E + +V+ Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVI---NYARSKKAALETAEEIEKL-GVKVLV 58 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 ++ N+ ++ + + +TFG+++ VNN L P + W + N Sbjct: 59 VKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALL 118 Query: 137 YMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 + + K GG IV+I + G ++A + LT+ LA+E + I Sbjct: 119 FCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQII 178 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +N V+ G I + + + E + Q PA R+ +++ V FL+S A I Sbjct: 179 VNAVSGGAIDTDAL--KHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIR 236 Query: 256 GQSVDVDGGRSLYTH 270 GQ++ VDGGRSL Sbjct: 237 GQTIIVDGGRSLLVL 251 >4Z9Y-A nrPDB Length = 253 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 126/257 (49%), Gaps = 11/257 (4%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 L LQG+VA++TG TG+G+ + L + G ++V + K +++ A Sbjct: 3 LNSFDLQGKVALITGCDTGLGQGMAIGLAQAGCDIV--GVNIVEPKDTIEKVTAL----- 55 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 R + + ++ N LV+ + FG ++ LVNN G A S K W V+ Sbjct: 56 GRRFLSLTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNL 115 Query: 131 NLTGTFYMCKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 N+ F+M + V ++K+ GG I+NI + + G A+++ V +T+ +A E Sbjct: 116 NIKSVFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANE 175 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 WA GI +N +APG + + + +S + +IPA R G+P+++ FL S Sbjct: 176 WAKHGINVNAIAPGYMATNNTQQLRADEERS--KEILDRIPAGRWGLPQDLMGPSVFLAS 233 Query: 249 PAASFITGQSVDVDGGR 265 A+ +I G ++ VDGG Sbjct: 234 SASDYINGYTIAVDGGW 250 >3V2G-A nrPDB Length = 271 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 67/262 (25%), Positives = 115/262 (43%), Gaps = 15/262 (5%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKL-ERLKSAADELQANL 66 +S + L G+ A VTGG+ GIG AI K L G+ V + ER ++ E+ Sbjct: 21 QSMMTSISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEI---- 76 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA 126 R + I+ + R+ E + ++ T++ G ++ LVN+ G +P E + + Sbjct: 77 -EQAGGRAVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDE 135 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKS 184 V+ N F ++ GG I+ I + +P A++A + LTK Sbjct: 136 VMAVNFRAPFVAIRSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKG 193 Query: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 LA + GI +N V PG + E ++I G P++++ +V Sbjct: 194 LARDLGPRGITVNIVHPGSTDTDM-----NPADGDHAEAQRERIATGSYGEPQDIAGLVA 248 Query: 245 FLLSPAASFITGQSVDVDGGRS 266 +L P F+TG S+ +DGG + Sbjct: 249 WLAGPQGKFVTGASLTIDGGAN 270 >1NFF-A nrPDB Length = 260 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 112/253 (44%), Gaps = 18/253 (7%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA 72 G L G+VA+V+GGA G+G + V+ ++ G+ VV DE + Sbjct: 2 SGRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGD--------ILDEEGKAMAAELAD 53 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 + ++ + V + + FG ++ LVNN G + E + W +L+ NL Sbjct: 54 AARYVHLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNL 113 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 TG F +AV + GSI+NI + AG A + V LTKS ALE Sbjct: 114 TGVFLGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGP 173 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 SGIR+N + PG++ + + + R P EVS++V +L S + Sbjct: 174 SGIRVNSIHPGLVKTPMT---------DWVPEDIFQTALGRAAEPVEVSNLVVYLASDES 224 Query: 252 SFITGQSVDVDGG 264 S+ TG VDGG Sbjct: 225 SYSTGAEFVVDGG 237 >5YSS-A nrPDB Length = 256 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 65/258 (25%), Positives = 120/258 (46%), Gaps = 15/258 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG +GIG I + L + G+ +++ AA + A T Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGD---VDAAKDAVAQYGKTPG---- 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ +E ++ ++++ FG ++ L+NN G Q +SP E W+A++ NL+ Sbjct: 56 YHGADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSV 115 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F+ + + G I+NI V AA+ GV LTK++ALE A + I Sbjct: 116 FHTTRLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEI 175 Query: 195 RINCVAPGVIYSQTAVENY------GSWGQSFFEGSF-QKIPAKRIGVPEEVSSVVCFLL 247 N + PG + + + G+ ++ + +K P++ PE++ ++ FL Sbjct: 176 TCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLC 235 Query: 248 SPAASFITGQSVDVDGGR 265 S A+ + G + ++DGG Sbjct: 236 SDGAAQVRGVAWNMDGGW 253 >4MOW-A nrPDB Length = 256 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 8/252 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+VAIVTG + GIG AI K L + G+ VV+ K+ AD + + + R + Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVV---NYASSKAGADAVVSAITEA-GGRAV 67 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ + +V + ++T+G+++ LVNN G +P E I+ + + +TN+ G Sbjct: 68 AVGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGV 127 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 +A G SI+NI V T P + + V +T LALE I Sbjct: 128 LLTTQAAVKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKI 185 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R+N + PG+I ++ + G G + P R+G P +++SV FL S A ++ Sbjct: 186 RVNAINPGMIVTE-GTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARWM 244 Query: 255 TGQSVDVDGGRS 266 TG+ + V GG + Sbjct: 245 TGEHLVVSGGLN 256 >1AHH-A nrPDB Length = 255 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 67/251 (26%), Positives = 116/251 (46%), Gaps = 10/251 (3%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L G+ AI+TG GIGK I G++VV++ + DE+Q + Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-----QLGGQA 62 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 +C+I +E+E++ L + GK++ LVNN GG P + + E N+ Sbjct: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFS 121 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F++ + V K GG I+ I + +++A +L +++A + Sbjct: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+N +APG I + + Q P +R+G P+++++ FL SPAAS+ Sbjct: 182 IRVNGIAPGAILTDALKSVI---TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 Query: 254 ITGQSVDVDGG 264 ++GQ + V GG Sbjct: 239 VSGQILTVSGG 249 >3RWB-A nrPDB Length = 247 Score = 214 bits (545), Expect = 5e-56, Method: Composition-based stats. Identities = 78/254 (30%), Positives = 112/254 (44%), Gaps = 13/254 (5%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L G+ A+VTG A GIGKAI L G+ V+++ E K+AA + + Sbjct: 2 ERLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI--------GKK 53 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 I +I + V L G I+ LVNN + + W +++ NLT Sbjct: 54 ARAIAADISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLT 113 Query: 134 GTFYMCKAVYSSWMKEHG-GSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 GTF + +A G +++I T AG P AA+ GV T++LA E Sbjct: 114 GTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGK 173 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 I N V PG+I S + + F E K G PE ++ VV FL S A Sbjct: 174 YNITANAVTPGLIESDGVKASPHNEAFGFVEMLQA---MKGKGQPEHIADVVSFLASDDA 230 Query: 252 SFITGQSVDVDGGR 265 +ITGQ+++VD G Sbjct: 231 RWITGQTLNVDAGM 244 >1K2W-A nrPDB Length = 256 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 73/261 (27%), Positives = 123/261 (47%), Gaps = 21/261 (8%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L G+ A++TG A GIG+A + + G+ V IA LE ++ A E+ Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEI--------GPAA 53 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 I ++ ++ ++ V LD +G I+ LVNN L+P I+ + + + N++G Sbjct: 54 CAIALDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSG 113 Query: 135 TFYMCKAVYSSWMK-EHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 T +M +AV + + GG I+N+ + G L A +A V +LT+S L Sbjct: 114 TLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRH 173 Query: 193 GIRINCVAPGVIYSQ---------TAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVV 243 GI +N +APGV+ + EN + +P R+G E+++ + Sbjct: 174 GINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKR--QVGAAVPFGRMGRAEDLTGMA 231 Query: 244 CFLLSPAASFITGQSVDVDGG 264 FL +P A +I Q+ +VDGG Sbjct: 232 IFLATPEADYIVAQTYNVDGG 252 >5EJ2-A nrPDB Length = 308 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 69/276 (25%), Positives = 120/276 (43%), Gaps = 23/276 (8%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS-----RKLERLKSAADELQ--ANL 66 G + G+VA ++G A G G++ L + G++++ L S ++L A+L Sbjct: 33 GRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADL 92 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS-PAEHISSKGWH 125 R++ Q ++R+ E + + V S ++ G+++ +V N G I W Sbjct: 93 VKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQ 152 Query: 126 AVLETNLTGTFYMCKAVYSS-WMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTK 183 +++ NLTG ++ KA GGSIV V + +P H AA+ GV L + Sbjct: 153 DMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMR 212 Query: 184 SLALEWACSGIRINCVAPGVIYSQTAV------------ENYGSWGQSFFEGSFQKIPAK 231 + A+E IR+N V P + + + EN G + +P Sbjct: 213 AFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP 272 Query: 232 RIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 ++S+ V FL S + ++TG S+ VD G L Sbjct: 273 -WVDASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >3WTC-A nrPDB Length = 262 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 72/260 (27%), Positives = 123/260 (47%), Gaps = 14/260 (5%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L G++A VTG A GIGKAI L + G++V++ K + L A E++A R Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEAL-----GRRA 59 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + + +I N ++ + + T G ++ +VNN G + P I + N+ G Sbjct: 60 VALTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQG 119 Query: 135 TFYMCKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 + +A + + ++ G I+N + G+PL A + V LT+S A E A S Sbjct: 120 VLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASS 179 Query: 193 GIRINCVAPGVIYSQT-------AVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 GI +N PG++ + E G+ + ++ + I R+ ++V+ V + Sbjct: 180 GITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAY 239 Query: 246 LLSPAASFITGQSVDVDGGR 265 L S A ++TGQSV +DGG Sbjct: 240 LSSSDADYMTGQSVLIDGGL 259 >2CFC-A nrPDB Length = 250 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 118/252 (46%), Gaps = 10/252 (3%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VAIVTG ++G G AI L G V E L+ A +V+ ++ Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETART----HWHAYADKVLRVR 58 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQF---LSPAEHISSKGWHAVLETNLTGT 135 ++ +E +VN + +T++ FG I+ LVNN G + + V+ N+ G Sbjct: 59 ADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGI 118 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F C+AV + + G IVNI V + FP ++ V LTKS+A+++A SGI Sbjct: 119 FLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGI 178 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R N V PG+I + + + +IP K IG +V+ V FL A+++ Sbjct: 179 RCNAVCPGMIETPMT--QWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYV 236 Query: 255 TGQSVDVDGGRS 266 G ++ +DG + Sbjct: 237 NGAALVMDGAYT 248 >3UF0-A nrPDB Length = 273 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 122/259 (47%), Gaps = 10/259 (3%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 +S P L G+ A+VTG +GIG+AI G++V+ R + +K ADE+ Sbjct: 21 QSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-DGVKEVADEIA---- 75 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 + ++ + E N+ + T +++ LVNN G +PAE +S W V Sbjct: 76 -DGGGSAEAVVADLADLEGAANVAEELAATR-RVDVLVNNAGIIARAPAEEVSLGRWREV 133 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 L NL + + ++ ++ + G IV I + + G A++ V LT++LA Sbjct: 134 LTVNLDAAWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALA 193 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 EWA G+ +N +APG + + ++ +IPA R PE++ FL Sbjct: 194 SEWAGRGVGVNALAPGYVVTANTAALRADDERA--AEITARIPAGRWATPEDMVGPAVFL 251 Query: 247 LSPAASFITGQSVDVDGGR 265 S AAS++ GQ + VDGG Sbjct: 252 ASDAASYVHGQVLAVDGGW 270 >2P91-A nrPDB Length = 285 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 59/272 (21%), Positives = 114/272 (41%), Gaps = 18/272 (6%) Query: 5 AKGRSYLAPGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADEL 62 KG ++ GLL+G+ A++TG A I I K G+ + +L+ E+ Sbjct: 10 NKGEVFM--GLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATP-KLEKRVREI 66 Query: 63 QANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG----GQFLSPAEH 118 + ++C++ +E++ NL K + +G ++ +V++ +F Sbjct: 67 AKGFGSD-----LVVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVID 121 Query: 119 ISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAG 177 S +G+ ++ ++ + + + M+ G+IV + + P G A+A Sbjct: 122 TSREGFKIAMDISVYSLIALTRELLP-LMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAA 180 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPE 237 + + + LA + A G RIN ++ G + + A G E + + P + E Sbjct: 181 LESTVRYLAYDIAKHGHRINAISAGPVKTLAAYSITGF--HLLMEHTTKVNPFGKPITIE 238 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDGGRSLYT 269 +V FL S A ITG+ V VD G + Sbjct: 239 DVGDTAVFLCSDWARAITGEVVHVDNGYHIMG 270 >3T7C-A nrPDB Length = 299 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 66/289 (22%), Positives = 127/289 (43%), Gaps = 24/289 (8%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS--RKLERLK-- 56 + + +G +A G ++G+VA +TG A G G++ L G++++ ++L+ +K Sbjct: 12 LEAQTQGPGSMA-GKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLP 70 Query: 57 -SAADELQANLPPTK--QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFL 113 S D+L + + R+I Q ++R+ + + V + G+++ ++ N Sbjct: 71 MSTPDDLAETVRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASE 130 Query: 114 SP-AEHISSKGWHAVLETNLTGTFYMCKAVYSSWMK-EHGGSIV-NIIVPTKAGFPLAVH 170 + K W +++ NL G + + M + GGSIV + G + Sbjct: 131 GTRLNRMDPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGN 190 Query: 171 SGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQT------------AVENYGSWGQ 218 A++ G++ L +++ALE IR+N V P + + +EN Sbjct: 191 YIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDF 250 Query: 219 SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 +P P ++S+ + FL+S A +ITG S+ VDGG L Sbjct: 251 QVASRQMHVLPIP-YVEPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >1W73-A nrPDB Length = 302 Score = 210 bits (535), Expect = 6e-55, Method: Composition-based stats. Identities = 90/265 (33%), Positives = 140/265 (52%), Gaps = 11/265 (4%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 ++ L P QG+VA +TGG TG+GK + L LG+ VIASRK++ LK+ A+++ + Sbjct: 16 KAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQ-- 73 Query: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 +V IQC++R+ + V N V + G N ++NN G F+SP E +S W + Sbjct: 74 --TGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTI 131 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGG----SIVNIIVPTKAGFPLAVHSGAARAGVYNLTK 183 + L GT ++ + +K G SI I + G V S +A+AGV ++K Sbjct: 132 TDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIY--AETGSGFVVPSASAKAGVEAMSK 189 Query: 184 SLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVV 243 SLA EW G+R N + PG I ++ A G +F + +IP R+G EE++++ Sbjct: 190 SLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTG-TFEKEMIGRIPCGRLGTVEELANLA 248 Query: 244 CFLLSPAASFITGQSVDVDGGRSLY 268 FL S AS+I G + DGG + Sbjct: 249 AFLCSDYASWINGAVIKFDGGEEVL 273 >4HP8-A nrPDB Length = 247 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 72/258 (27%), Positives = 114/258 (44%), Gaps = 16/258 (6%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 P L+G+ A+VTG TG+G+AI L G+ VV A+R+ A + ++ Sbjct: 1 MKNPFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARR-------APDETLDIIAK 53 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 + + + + + LVNN G + + S W V++ Sbjct: 54 DGGNASALLIDFADPLAAKDSFTDA-----GFDILVNNAGIIRRADSVEFSELDWDEVMD 108 Query: 130 TNLTGTFYMCKAVYSSWM-KEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLAL 187 NL F+ +A + K G +VNI + + G AA+ GV LTK LA Sbjct: 109 VNLKALFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLAN 168 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 EWA GI +N +APG I + ++ + ++IPA R G E+++ FL Sbjct: 169 EWAAKGINVNAIAPGYIETNNTEALRADAARN--KAILERIPAGRWGHSEDIAGAAVFLS 226 Query: 248 SPAASFITGQSVDVDGGR 265 S AA ++ G ++VDGG Sbjct: 227 SAAADYVHGAILNVDGGW 244 >4ZJU-A nrPDB Length = 275 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 57/275 (20%), Positives = 105/275 (38%), Gaps = 15/275 (5%) Query: 11 LAPGLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 + GLL G+ ++ G A+ I I + L G+ + E+LK DE Sbjct: 9 MTQGLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPN-EKLKKRVDEFAEQFGS 67 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG----QFLSPAEHISS-KG 123 + C++ + E++N + ++ +V++ G ++ G Sbjct: 68 K-----LVFPCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDG 122 Query: 124 WHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTK 183 + + + M +A G + ++ P G A+A + + Sbjct: 123 FKIAHDISAYSFVAMARAAKPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVR 182 Query: 184 SLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVV 243 LA GIR+N ++ G I + A + + + + + P KR EEV + Sbjct: 183 YLASSLGVDGIRVNAISAGPIRTLAA--SGIKSFRKMLDANEKVAPLKRNVTIEEVGNAA 240 Query: 244 CFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHD 278 FL SP AS ITG+ + VD G + S + D + Sbjct: 241 LFLCSPWASGITGEILYVDAGFNTVGMSQSMMDDE 275 >2B4Q-A nrPDB Length = 276 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 70/268 (26%), Positives = 121/268 (45%), Gaps = 14/268 (5%) Query: 6 KGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 +G L G++A+VTGG+ GIG+ I + LLE G+ V I +R E A L A Sbjct: 17 RGSHMHPYFSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSA- 75 Query: 66 LPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWH 125 I ++ +E L ++ + +++ LVNN G + + E GW Sbjct: 76 -----YGDCQAIPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWE 130 Query: 126 AVLETNLTGTFYMCKAVYSSWMK----EHGGSIVNI-IVPTKAGFPLAVH-SGAARAGVY 179 V++ N+T F + + + E+ ++NI V + + G ++A ++ Sbjct: 131 KVMQLNVTSVFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALH 190 Query: 180 NLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 L++ LA E I +N +APG S+ + + E IP R G PEE+ Sbjct: 191 QLSRMLAKELVGEHINVNVIAPGRFPSRMT--RHIANDPQALEADSASIPMGRWGRPEEM 248 Query: 240 SSVVCFLLSPAASFITGQSVDVDGGRSL 267 +++ L A +++TG + +DGG L Sbjct: 249 AALAISLAGTAGAYMTGNVIPIDGGFHL 276 >1DOH-A nrPDB Length = 283 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 61/264 (23%), Positives = 119/264 (45%), Gaps = 17/264 (6%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+G+VA+VTG GIG+ + EL G V++ +A+E+ A + Sbjct: 26 SLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYAN---STESAEEVVAAIKKNGSDAA 82 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 ++ N+ E++ + + + FGK++ + +N G + ++ + + V N G Sbjct: 83 C-VKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRG 141 Query: 135 TFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 F++ + Y E GG ++ + I P ++ + + +A++ A Sbjct: 142 QFFVAREAYKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADK 199 Query: 193 GIRINCVAPGVIYSQT---AVENYGSWGQSFFE------GSFQKIPAKRIGVPEEVSSVV 243 I +N VAPG I + Y G++ + Q P +R+G+P +++ VV Sbjct: 200 KITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVV 259 Query: 244 CFLLSPAASFITGQSVDVDGGRSL 267 CFL S ++TG+ + +DGG + Sbjct: 260 CFLASNDGGWVTGKVIGIDGGACM 283 >4E6P-A nrPDB Length = 259 Score = 206 bits (525), Expect = 9e-54, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 124/259 (47%), Gaps = 17/259 (6%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+G+ A++TG A GIG+A + + G+ V IA +ER + AA E+ Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEI--------GPAA 56 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 +Q ++ ++ ++ + +T++ G ++ LVNN L+P I+ + + + N+ G Sbjct: 57 YAVQMDVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAG 116 Query: 135 TFYMCKAVYSSWMKE-HGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 T + +A + + GG I+N+ + G L A +A V +LT+S L+ Sbjct: 117 TLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKH 176 Query: 193 GIRINCVAPGVIYS------QTAVENYGSWGQSFFEGSF-QKIPAKRIGVPEEVSSVVCF 245 I +N +APGV+ Y + + + + +P R+G E+++ + F Sbjct: 177 RINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIF 236 Query: 246 LLSPAASFITGQSVDVDGG 264 L S + +I Q+ +VDGG Sbjct: 237 LASAESDYIVSQTYNVDGG 255 >3D3W-A nrPDB Length = 244 Score = 205 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 61/253 (24%), Positives = 104/253 (41%), Gaps = 17/253 (6%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L G+ +VTG GIG+ V+ L G+ VV SR L S E + Sbjct: 4 FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG---------I 54 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 P+ ++ + E + S G ++ LVNN L P ++ + + E NL Sbjct: 55 EPVCVDLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRA 110 Query: 135 TFYMCKAVYSSWMKEH-GGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 + + V + G+IVN+ ++ + + + LTK +ALE Sbjct: 111 VIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPH 170 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 IR+N V P V+ + + ++ + +IP + E V + + FLLS + Sbjct: 171 KIRVNAVNPTVVMTSMGQATWSDPHKA--KTMLNRIPLGKFAEVEHVVNAILFLLSDRSG 228 Query: 253 FITGQSVDVDGGR 265 TG ++ V+GG Sbjct: 229 MTTGSTLPVEGGF 241 >3A28-C nrPDB Length = 258 Score = 205 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 65/257 (25%), Positives = 120/257 (46%), Gaps = 14/257 (5%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA+VTGGA GIG+ I ++L G ++ +A + + AA+ ++ L + + + Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQE-EQAAETIK--LIEAADQKAVFVG 59 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ ++ ++ + + G + LVNN G + P ++ + + N+ F+ Sbjct: 60 LDVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFG 119 Query: 139 CKAVYSSW--MKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 +A + + G I + GFP+ + V LT++ A E A G + Sbjct: 120 IQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTV 179 Query: 197 NCVAPGVIYSQTAVE--------NYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 N APG++ + + N G++F E S I R VPE+V+ +V FL S Sbjct: 180 NAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYS-SSIALGRPSVPEDVAGLVSFLAS 238 Query: 249 PAASFITGQSVDVDGGR 265 ++++TGQ + VDGG Sbjct: 239 ENSNYVTGQVMLVDGGM 255 >1O5I-A nrPDB Length = 249 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 64/253 (25%), Positives = 117/253 (46%), Gaps = 24/253 (9%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 + + +V + GIG+A+ L + G+ V I +R E LK + Sbjct: 18 RDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSGHR--------------Y 63 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 + C++R +++ L + + ++ LV N GG + ++++ + +++ Sbjct: 64 VVCDLRK--DLDLLFEKVKE----VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMI 117 Query: 137 YMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 + + + ++ G IV I + S +AR + K+L+ E A GI Sbjct: 118 KIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGIT 177 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +NCVAPG ++ E + E +IP +R+ PEE++SVV FL S AS++T Sbjct: 178 VNCVAPGWTETERVKELLSEEKKKQVE---SQIPMRRMAKPEEIASVVAFLCSEKASYLT 234 Query: 256 GQSVDVDGGRSLY 268 GQ++ VDGG S + Sbjct: 235 GQTIVVDGGLSKF 247 >5JY1-A nrPDB Length = 274 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 72/273 (26%), Positives = 124/273 (45%), Gaps = 17/273 (6%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 GLL+ +VA+VTG GIG+ + + G+ V+IA + E++ R Sbjct: 10 GLLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIRE-----MGGR 64 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS-PAEHISSKGWHAVLETNL 132 + ++ ++ ++ + V+S ++ FG ++ LVNN + E + + L T+L Sbjct: 65 SLFVKTDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSL 124 Query: 133 TGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 T++ +A + + G IVN + T+ G L A+AG+ LT+S A EW Sbjct: 125 WATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGR 184 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPE-EVSSVVCFLLSPA 250 I +N +AP + + F E S P R G PE ++ F S Sbjct: 185 FNITVNAIAPTAM--GATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEM 242 Query: 251 ASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 283 + F+TG+++ VDGG L P +++ P G Sbjct: 243 SRFVTGETLHVDGGLHL-------PGYNSRPAG 268 >1H5Q-A nrPDB Length = 265 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 75/272 (27%), Positives = 124/272 (45%), Gaps = 20/272 (7%) Query: 9 SYLAPGL---LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 S++APG + IVTGG GIG A + + G+NV + R + A E+ Sbjct: 2 SHMAPGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSA----ADAVEVTEK 57 Query: 66 LPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWH 125 + + QC++ N + V ++ G I+ L+ N G + PA ++ + + Sbjct: 58 VGKEFGVKTKAYQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFA 117 Query: 126 AVLETNLTGTFYMCKAVYSSWM-KEHGGSIVNIIV--------PTKAGFPLAVHSGAARA 176 V + N+ G F C+AV W+ K+ GSIV + G V +++A Sbjct: 118 FVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKA 177 Query: 177 GVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVP 236 NL K LA EWA +GIR+N ++PG + + + + IP R P Sbjct: 178 ACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTAH----MDKKIRDHQASNIPLNRFAQP 233 Query: 237 EEVSSVVCFLLSPAASFITGQSVDVDGGRSLY 268 EE++ LLS A+++TG +DGG+ ++ Sbjct: 234 EEMTGQAILLLSDHATYMTGGEYFIDGGQLIW 265 >2HSD-A nrPDB Length = 253 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 82/254 (32%), Positives = 119/254 (46%), Gaps = 13/254 (5%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L G+ I+TGGA G+G ++ + G+ VV+A E + A EL Sbjct: 1 NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL--------GDA 52 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 ++ EE+ +V + FG ++ LVNN G E S + + V+E NLT Sbjct: 53 ARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLT 112 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 G F K V + GGSIVNI G L GA++ GV L+K A+E Sbjct: 113 GVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTD 172 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 IR+N V PG+ Y+ E G EG++ P R+G P E++ V LLS +S Sbjct: 173 RIRVNSVHPGMTYTPMTAET----GIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSS 228 Query: 253 FITGQSVDVDGGRS 266 ++TG + VDGG + Sbjct: 229 YVTGAELAVDGGWT 242 >5B1Y-A nrPDB Length = 270 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 114/253 (45%), Gaps = 8/253 (3%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 ++ A+VTGG+ GIG+A V G +VVIA + L A++ Sbjct: 21 METTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADL---AEKTAEEARRLGSPEAY 77 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ ++ + + V + + +N LVN G L E S W L NLTG Sbjct: 78 TVRVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGV 137 Query: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLA-VHSGAARAGVYNLTKSLALEWACSG 193 + + K + K SIVN+ + + G +A V A++AGV LTK LA++ A G Sbjct: 138 YLVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYG 197 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP-AAS 252 IR+N VAP + + + + E P K I PE+V+ + FL P + Sbjct: 198 IRVNAVAPSFVETDMTRSFLDTPEKR--ERIASLHPLKIILKPEDVAEAILFLADPRRSR 255 Query: 253 FITGQSVDVDGGR 265 ITG + ++ GR Sbjct: 256 GITGHVLSINAGR 268 >3GDF-A nrPDB Length = 267 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 72/267 (26%), Positives = 120/267 (44%), Gaps = 13/267 (4%) Query: 5 AKGRSYLAPGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADEL 62 K S L L+G+V +VTG + G+G + E+G+ V I + A+E Sbjct: 7 TKHESLLDQLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQG---AEEN 63 Query: 63 QANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK 122 L T + +C + + E LVK + FG+I+ + N G S S + Sbjct: 64 VKELEKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVE 123 Query: 123 GWHAVLETNLTGTFYMCKAVYSSWMKEHGGS--IVNIIVPTKAGFPL-AVHSGAARAGVY 179 W+ V++ +L GTF+ KAV + + GS I + A FP A+AG Sbjct: 124 AWNHVVQVDLNGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCI 183 Query: 180 NLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 ++ +SLA EW R+N ++PG I + + ++ S IP R G+ +E+ Sbjct: 184 HMARSLANEW-RDFARVNSISPGYIDT--GLSDFVPKETQQLWHSM--IPMGRDGLAKEL 238 Query: 240 SSVVCFLLSPAASFITGQSVDVDGGRS 266 + S A+++ TG + +DGG + Sbjct: 239 KGAYVYFASDASTYTTGADLLIDGGYT 265 >3OIG-A nrPDB Length = 266 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 62/261 (23%), Positives = 109/261 (41%), Gaps = 15/261 (5%) Query: 14 GLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 L+G+ +V G A I I + L E G+ ++ ERL+ + EL L Sbjct: 3 FSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAG-ERLEKSVHELAGTLDRNDS 61 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG----QFLSPAEHISSKGWHAV 127 I + C++ N+ E+ S + G I+ + + + + + + G+ + Sbjct: 62 ---IILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGF--L 116 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 L N++ + M GGSIV + + + P G A+A + K LA Sbjct: 117 LAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLA 176 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 + IR+N ++ G I + +A S S + ++ P +R PEEV FL Sbjct: 177 ADLGKENIRVNSISAGPIRTLSA--KGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFL 234 Query: 247 LSPAASFITGQSVDVDGGRSL 267 S + ITG+++ VD G + Sbjct: 235 FSDMSRGITGENLHVDSGFHI 255 >2AG5-A nrPDB Length = 246 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 57/258 (22%), Positives = 104/258 (40%), Gaps = 18/258 (6%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 G L G+V I+T A GIG+A G+ V+ +L+ K Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----------EKYPG 51 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 + ++ +++++ +++ L N G K W + N+ Sbjct: 52 IQTRVLDVTKKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNIIV--PTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 + M KA + + G+I+N+ + G +A V LTKS+A ++ Sbjct: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 Query: 192 SGIRINCVAPGVIYSQTAVENYGS--WGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 GIR NCV PG + + + E + + ++ R EE++ + +L S Sbjct: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 Query: 250 AASFITGQSVDVDGGRSL 267 ++++TG V +DGG SL Sbjct: 228 ESAYVTGNPVIIDGGWSL 245 >3UN1-A nrPDB Length = 260 Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats. Identities = 68/254 (26%), Positives = 118/254 (46%), Gaps = 28/254 (11%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 Q +V ++TG + GIG +V+ + VV SR + P+ + Sbjct: 27 QQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRS--------------IKPSADPDIHT 72 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 + +I E + +V+ ++ FG+I+ LVNN G P ++ + + L N+ G F Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFF 132 Query: 137 YMCKAVYSSWMKEHGGSIVNIIVP----TKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 ++ + + +K+ G IV+I G P A+ S + G+ +T+SLA+E++ S Sbjct: 133 HITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALAS-LTKGGLNAVTRSLAMEFSRS 191 Query: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 G+R+N V+PGVI + P R+G +V V +L A Sbjct: 192 GVRVNAVSPGVIKTPM-------HPAETHSTLAGLHPVGRMGEIRDVVDAVLYL--EHAG 242 Query: 253 FITGQSVDVDGGRS 266 FITG+ + VDGG++ Sbjct: 243 FITGEILHVDGGQN 256 >4AVY-A nrPDB Length = 242 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 110/250 (44%), Gaps = 21/250 (8%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 GQ +VTGG++GIG AI + ELG+ VV + + + + R+ Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHA-----------PRHPRIRR 58 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 + +I + + + L ++ +++ LVNN G E + VL NL+ Sbjct: 59 EELDITDSQRLQRLFEALP----RLDVLVNNAGISRDR--EEYDLATFERVLRLNLSAAM 112 Query: 137 YMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 + + + GGSI+NI + G A++ + LT+SLA E+A IR Sbjct: 113 LASQLA-RPLLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIR 171 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFIT 255 +N +APG I + + Q+ P R G EV+S FL P ASF+T Sbjct: 172 VNAIAPGWIDTPLGAGLKADVEATRR--IMQRTPLARWGEAPEVASAAAFLCGPGASFVT 229 Query: 256 GQSVDVDGGR 265 G + VDGG Sbjct: 230 GAVLAVDGGY 239 >3U4C-A nrPDB Length = 281 Score = 196 bits (499), Expect = 9e-51, Method: Composition-based stats. Identities = 67/258 (25%), Positives = 116/258 (44%), Gaps = 13/258 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + + A V G + GIGKAI +L + ++VI SR L+ ++S +++ A P A VI Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPE---ASVI 77 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ ++ + + G+++ L+NN G ++ + + A Sbjct: 78 VLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAY 137 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAV--HSGAARAGVYNLTKSLALEWACSG 193 K S + G I+NI V P A + A + N +K+++++ A Sbjct: 138 IDAIKRASSLMKQNEFGRIINI-VGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHN 196 Query: 194 IRINCVAPGVIYSQT-------AVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 I +NC+ PG I + ++ Q E IP KR+G EE +++ FL Sbjct: 197 ITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFL 256 Query: 247 LSPAASFITGQSVDVDGG 264 S AS+ITGQ + DGG Sbjct: 257 ASEEASYITGQQISADGG 274 >2YW9-A nrPDB Length = 261 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 15/264 (5%) Query: 16 LQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L G+ A+V G +G AI +L E G+ V ++ + ERL+ A++L L Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSY-QAERLRPEAEKLAEAL-----GG 59 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE----HISSKGWHAVLE 129 + + ++ +EE++ L + FG +++LV+ E + W LE Sbjct: 60 ALLFRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALE 119 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 + + + ++E GG + ++ P A+A + + LA E Sbjct: 120 VSAYSLVAVARRAEP-LLREGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYEL 178 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 G+R+N ++ G + + A G ++ Q P +R EEV ++ FLLSP Sbjct: 179 GPKGVRVNAISAGPVRTVAARSIPGFT--KMYDRVAQTAPLRRNITQEEVGNLGLFLLSP 236 Query: 250 AASFITGQSVDVDGGRSLYTHSYE 273 AS ITG+ V VD G + E Sbjct: 237 LASGITGEVVYVDAGYHIMGMELE 260 >5YCX-A nrPDB Length = 266 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 15/264 (5%) Query: 14 GLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 LLQG+ +V G A I I + L G+ ++ ERL+ EL L Sbjct: 4 ELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAG-ERLERNVRELADTLE---G 59 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP----AEHISSKGWHAV 127 + + C++ N+EE+ ++ G I+ + + S G+ + Sbjct: 60 QESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGF--L 117 Query: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 L N++ A + + GG+I+ + + + G A+A + K LA Sbjct: 118 LAQNISAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLA 177 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 + GIR+N ++ G I + + + G + S ++ P +R EEV FL Sbjct: 178 NDLGQHGIRVNAISAGPIRT-LSAKGVGDFN-SILREIEERAPLRRTTTQEEVGDTAVFL 235 Query: 247 LSPAASFITGQSVDVDGGRSLYTH 270 S A +TG+++ VD G + Sbjct: 236 FSDLARGVTGENIHVDSGYHILGL 259 >1CYD-A nrPDB Length = 244 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 62/252 (24%), Positives = 106/252 (42%), Gaps = 17/252 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G A+VTG GIG+ VK L G+ VV +R L S A E + Sbjct: 5 FSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG---------IE 55 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 P+ ++ + + + L G ++ LVNN + P ++ + + NL Sbjct: 56 PVCVDLGDWD----ATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSV 111 Query: 136 FYMCKAVYSSWMKEH-GGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F + + V + GSIVN+ FP + + + + LTK++A+E Sbjct: 112 FQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHK 171 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASF 253 IR+N V P V+ + + S F ++ P ++ E+V + + FLLS ++ Sbjct: 172 IRVNSVNPTVVLTDMGKKV--SADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSAS 229 Query: 254 ITGQSVDVDGGR 265 +G + VD G Sbjct: 230 TSGGGILVDAGY 241 >2FWM-X nrPDB Length = 250 Score = 193 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 63/259 (24%), Positives = 107/259 (41%), Gaps = 22/259 (8%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G+ VTG GIG A +E G+ V + +Q Sbjct: 5 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFT---------------QEQYPFA 49 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ + +V + + L +++ LVN G + + +S + W N+ G Sbjct: 50 TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 109 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFP-LAVHSGAARAGVYNLTKSLALEWACSGI 194 F + + + + ++ GG+IV + GA++A + +L S+ LE A SG+ Sbjct: 110 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 169 Query: 195 RINCVAPGVIYSQTAVENYGSWGQS------FFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 R N V+PG + + S F E IP +I P+E+++ + FL S Sbjct: 170 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 229 Query: 249 PAASFITGQSVDVDGGRSL 267 AS IT Q + VDGG +L Sbjct: 230 DLASHITLQDIVVDGGSTL 248 >4EGF-A nrPDB Length = 266 Score = 193 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 70/260 (26%), Positives = 111/260 (42%), Gaps = 8/260 (3%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 Y L G+ A++TG GIG I + G+ +V++ R + L +A L Sbjct: 12 YAGVLRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQF--- 68 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 V + ++ + L + + FG ++ LVNN G P + + A + Sbjct: 69 -GTDVHTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIA 127 Query: 130 TNLTGTFYMCKAVYSSWMKEH-GGSIVNIIVPTKAGFPLAVH-SGAARAGVYNLTKSLAL 187 NL + AV + + GG+I+ + + ++AG+ TK LA Sbjct: 128 VNLRAPALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLAR 187 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 E GIR N V P V+ ++ +G +S +IP R VP EVS V +L Sbjct: 188 ELGPHGIRANSVCPTVVLTEMGQRVWGDEAKS--APMIARIPLGRFAVPHEVSDAVVWLA 245 Query: 248 SPAASFITGQSVDVDGGRSL 267 S AAS I G + VDGG ++ Sbjct: 246 SDAASMINGVDIPVDGGYTM 265 >5O3Z-A nrPDB Length = 263 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 113/260 (43%), Gaps = 13/260 (5%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 QVA+V GG +G + + L + G +V +A AD + + R + Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGA---GRAYGFK 63 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 + +E V L ++ +TFG+ + LV + G +P + L+ NL G F Sbjct: 64 VDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLC 123 Query: 139 CKAVYSSWMKEH-GGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 + +++ G I+ I K G AA+ G LT+SLAL+ A GI + Sbjct: 124 SREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITV 183 Query: 197 NCVAPG-VIYSQTA-------VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 + + G ++ S E G + K+P KR ++V +V+ F S Sbjct: 184 HSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYAS 243 Query: 249 PAASFITGQSVDVDGGRSLY 268 A++ TGQS++V GG+ ++ Sbjct: 244 DKAAYCTGQSINVTGGQVMF 263 >4TRR-A nrPDB Length = 269 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 71/262 (27%), Positives = 118/262 (45%), Gaps = 15/262 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+ A+VTG A+GIGK I EL + G+ V IA + + ADE+ + I Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEI-----NKAGGKAI 66 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++ NEE VN + + FG ++ LV+N G Q ++P E+ S W + ++ G Sbjct: 67 GVAMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGA 126 Query: 136 FYMCKAVYSSWMK-EHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 F KA K + GG ++ + V + PL A+ G+ L + LA E A Sbjct: 127 FLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHN 186 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSF---FEGSFQKIPAKR-----IGVPEEVSSVVCF 245 +R + V PG + + + + E +K+ ++V+ V F Sbjct: 187 VRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLF 246 Query: 246 LLSPAASFITGQSVDVDGGRSL 267 L + ++ +TGQS V G + Sbjct: 247 LSAFPSAALTGQSFIVSHGWFM 268 >1HXH-A nrPDB Length = 253 Score = 190 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 20/263 (7%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 LQG+VA+VTGGA+G+G +VK LL G+ V + + A EL R Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGE--------R 53 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 + ++ ++ +E + ++ + G +N LVNN G E + + +L+ N Sbjct: 54 SMFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTE 113 Query: 134 GTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 F C+ ++ KE GGSI+N+ V + A++A V LT++ AL Sbjct: 114 SVFIGCQQGIAAM-KETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQ 172 Query: 193 G--IRINCVAPGVIYSQT---AVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247 G IR+N + P IY+ ++ S + + A R +PE ++ +V FL Sbjct: 173 GYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNR--AGRAYMPERIAQLVLFLA 230 Query: 248 SPAASFITGQSVDVDG---GRSL 267 S +S ++G + D G L Sbjct: 231 SDESSVMSGSELHADNSILGMGL 253 >5TF4-A nrPDB Length = 274 Score = 190 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 60/282 (21%), Positives = 110/282 (39%), Gaps = 23/282 (8%) Query: 3 SWAKGRSYLAPGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 S AKG GLL G+ ++ G A I I K G+ + + E +K + Sbjct: 2 SMAKGN-----GLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQG-EAMKKRVE 55 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG----QFLSPA 116 L + C++ + ++ + + +GK++FLV+ G + Sbjct: 56 PLAEEVKGFVCGH-----CDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRY 110 Query: 117 EHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAAR 175 IS + + ++ + K GGSI+ + + P G A+ Sbjct: 111 VDISESNFMMTMNISVYSLTALTKRAEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAK 168 Query: 176 AGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV 235 A + K LA++ IR+N ++ G I + A G + + + + P +R Sbjct: 169 AALEASVKYLAVDLGPKHIRVNAISAGPIKT-LAASGIGDF-RYILKWNEYNAPLRRTVT 226 Query: 236 PEEVSSVVCFLLSPAASFITGQSVDVDGGRSLY-THSYEVPD 276 EEV +LLS + +TG+ VD G ++ + + PD Sbjct: 227 IEEVGDSALYLLSDLSRSVTGEVHHVDSGYNIIGMKAVDAPD 268 >3V8B-A nrPDB Length = 283 Score = 190 bits (482), Expect = 9e-49, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 114/260 (43%), Gaps = 18/260 (6%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA++TG +GIG+A L G V R ++ ADE+ + I ++ Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVG-----AGGQAIALEA 84 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ-FLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ +E ++ N V+ + FG ++ +V N G +P + + W + NL GTF Sbjct: 85 DVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLT 144 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGF-----PLAVHSGAARAGVYNLTKSLALEWACSG 193 + GG+IV +V + G P A A +A + + LALE Sbjct: 145 LHLTVPYLKQRGGGAIV--VVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHH 202 Query: 194 IRINCVAPGVIYSQTAVENYGSWGQSF---FEGSFQKIPA--KRIGVPEEVSSVVCFLLS 248 IR+N V PG I + + + E ++P + G E+V+ ++ FL+S Sbjct: 203 IRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVS 262 Query: 249 PAASFITGQSVDVDGGRSLY 268 A +TG V +DGG+ L Sbjct: 263 ERARHVTGSPVWIDGGQGLL 282 >5JS6-A nrPDB Length = 274 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 109/237 (45%), Gaps = 15/237 (6%) Query: 35 VKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKST 94 V+ + G+ VVI + ++ EL + I C++ E++V LV T Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPG---------AVFILCDVTQEDDVKTLVSET 78 Query: 95 LDTFGKINFLVNNGGG-QFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGS 153 + FG+++ +VNN G E S++G+ +LE NL GT+ + K K G Sbjct: 79 IRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNV 138 Query: 154 IVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQT---AV 210 I + G AV A + V +TK+LAL+ + G+R+NC++PG I++ Sbjct: 139 INISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELA 198 Query: 211 ENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 + EG + P R+G P EV + FL S A+F TG + V GG L Sbjct: 199 ALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 253 >5KOI-A nrPDB Length = 293 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 48/270 (17%), Positives = 112/270 (41%), Gaps = 24/270 (8%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKL---ERLKSAADELQANLPP 68 GL+QG+ ++ G A + I K+L G+ + + +R+K A+++ ++ Sbjct: 24 GLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDF-- 81 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA-----EHISSKG 123 + C++ + V+ + + +G ++FLV+ G + + + + Sbjct: 82 -------VLPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTREN 134 Query: 124 WHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLT 182 + + + + + + GGSI+ + + P G A+A + + Sbjct: 135 FSRTMVISAYSFTEVAQRAEKLM--KDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMV 192 Query: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSV 242 + LA ++ GIR+N ++ G + + ++ F + P +R ++V Sbjct: 193 RYLAADYGPQGIRVNAISAGPVRTLAGA--GIGDARAIFSYQRRNSPLRRTVDIDDVGKS 250 Query: 243 VCFLLSPAASFITGQSVDVDGGRSLYTHSY 272 +LLS +S +TG+ VD G ++ + Sbjct: 251 AVYLLSDLSSGVTGEIHFVDSGYNIVSMPT 280 >3GRK-A nrPDB Length = 293 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 56/282 (19%), Positives = 109/282 (38%), Gaps = 18/282 (6%) Query: 3 SWAKGRSYLAPGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 + G GLLQG+ ++ G A I I K E G+ + + + LK + Sbjct: 16 TQGPGSMTAQSGLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQG-DALKKRVE 74 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG----QFLSPA 116 L L + C++ + ++ + ++ +GK++FLV+ G + Sbjct: 75 PLAEELGA-----FVAGHCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRY 129 Query: 117 EHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAAR 175 S + + ++ + + GGSI+ + + P G A+ Sbjct: 130 IDTSEANFTNTMLISVYSLTAVSRRAEKLM--ADGGSILTLTYYGAEKVMPNYNVMGVAK 187 Query: 176 AGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV 235 A + K LA++ IR+N ++ G I + A G + + + + P +R Sbjct: 188 AALEASVKYLAVDLGPQNIRVNAISAGPIKT-LAASGIGDF-RYILKWNEYNAPLRRTVT 245 Query: 236 PEEVSSVVCFLLSPAASFITGQSVDVDGGRSLY-THSYEVPD 276 +EV V + LS + +TG+ D G + + + PD Sbjct: 246 IDEVGDVGLYFLSDLSRSVTGEVHHADSGYHVIGMKAVDAPD 287 >5CFZ-A nrPDB Length = 305 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 52/265 (19%), Positives = 105/265 (39%), Gaps = 16/265 (6%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 G L G+ +VTG A+ I I + + G+ + + ++LK +E A L Sbjct: 45 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSD-- 101 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-----HISSKGWHA 126 I +QC++ + ++ + + K + V++ G + ++ +G+ Sbjct: 102 ---IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKI 158 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 + + M KA S + + + + P G A+A + + +A Sbjct: 159 AHDISSYSFVAMAKAC-RSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 217 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 G+R+N ++ G I + A + + P +R E+V + FL Sbjct: 218 NAMGPEGVRVNAISAGPIRTLAA--SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 275 Query: 247 LSPAASFITGQSVDVDGGRSLYTHS 271 S ++ I+G+ V VDGG S+ + Sbjct: 276 CSDLSAGISGEVVHVDGGFSIAAMN 300 >4M89-A nrPDB Length = 261 Score = 185 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 64/271 (23%), Positives = 109/271 (40%), Gaps = 23/271 (8%) Query: 14 GLLQGQVAIVTG--GATGIGKAIVKELLELGSNVVIA---SRKLERLKSAADELQANLPP 68 G LQG+ ++TG I I K E G+ + + ER++ A EL + L Sbjct: 2 GFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSEL-- 59 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ-----FLSPAEHISSKG 123 +C++ +++E+N + + ++ LV++ G + IS + Sbjct: 60 -------VFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREA 112 Query: 124 WHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLT 182 ++ E + + KA M+ +IV + P G A+A + Sbjct: 113 FNTAHEISAYSLPALAKAA-RPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGI 171 Query: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSV 242 + A GIR N ++ G I + A +G+ + P +R EEV + Sbjct: 172 RFTAACLGKEGIRCNGISAGPIKT-LAASGIADFGKLLGHVAAHN-PLRRNVTIEEVGNT 229 Query: 243 VCFLLSPAASFITGQSVDVDGGRSLYTHSYE 273 FLLS +S ITG+ VDGG S+ S E Sbjct: 230 AAFLLSDLSSGITGEITYVDGGYSINALSTE 260 >4JQC-A nrPDB Length = 282 Score = 185 bits (469), Expect = 3e-47, Method: Composition-based stats. Identities = 52/265 (19%), Positives = 105/265 (39%), Gaps = 16/265 (6%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 G L G+ +VTG A+ I I + + G+ + + ++LK +E A L Sbjct: 22 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSD-- 78 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE-----HISSKGWHA 126 I +QC++ + ++ + + K + V++ G + ++ +G+ Sbjct: 79 ---IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKI 135 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 + + M KA S + + + + P G A+A + + +A Sbjct: 136 AHDISSYSFVAMAKAC-RSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 194 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 G+R+N ++ G I + A + + P +R E+V + FL Sbjct: 195 NAMGPEGVRVNAISAGPIRTLAA--SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 252 Query: 247 LSPAASFITGQSVDVDGGRSLYTHS 271 S ++ I+G+ V VDGG S+ + Sbjct: 253 CSDLSAGISGEVVHVDGGFSIAAMN 277 >3K2E-A nrPDB Length = 296 Score = 184 bits (468), Expect = 4e-47, Method: Composition-based stats. Identities = 55/285 (19%), Positives = 110/285 (38%), Gaps = 19/285 (6%) Query: 1 MASWAKGRSYLAPGLL-QGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKS 57 + + +G + G+L +G+ ++ G A + I K + G+ V + E K Sbjct: 12 LEAQTQGPGSMRTGMLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLS-ETFKK 70 Query: 58 AADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG----QFL 113 D L +L + + C++ + E V+N+ K + +G ++F+V+ + Sbjct: 71 RVDPLAESLGVK-----LTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELK 125 Query: 114 SPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSG 172 S + + + Y+ +GGSI+ + + P G Sbjct: 126 GRYVDTSLGNFLTSMHISCYSFTYIASKAEPLM--TNGGSILTLSYYGAEKVVPHYNVMG 183 Query: 173 AARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKR 232 +A + K LA++ IR+N ++ G + + + S + P +R Sbjct: 184 VCKAALEASVKYLAVDLGKQQIRVNAISAGPVRT--LASSGISDFHYILTWNKYNSPLRR 241 Query: 233 IGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLY-THSYEVPD 276 ++V +LLS TG++V VD G + S + PD Sbjct: 242 NTTLDDVGGAALYLLSDLGRGTTGETVHVDCGYHVVGMKSVDAPD 286 >4ALL-A nrPDB Length = 277 Score = 183 bits (466), Expect = 5e-47, Method: Composition-based stats. Identities = 63/268 (23%), Positives = 112/268 (41%), Gaps = 18/268 (6%) Query: 6 KGRSYLAPGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADELQ 63 +GR L L+ + ++ G A I + K L +LG+ +V RK K EL+ Sbjct: 18 EGRHMLN---LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRK----ELE 70 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP----AEHI 119 L Q Q +++++EEV N + G I+ + ++ + Sbjct: 71 KLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSET 130 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGV 178 S +G+ +L +++ A + + GGSIV + + G A+A + Sbjct: 131 SREGF--LLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASL 188 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 K LAL+ IR+N ++ G I + +A G + + ++ P KR E Sbjct: 189 EANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFN--TILKEIEERAPLKRNVDQVE 246 Query: 239 VSSVVCFLLSPAASFITGQSVDVDGGRS 266 V +LLS +S +TG+++ VD G Sbjct: 247 VGKTAAYLLSDLSSGVTGENIHVDSGFH 274 >2X9N-A nrPDB Length = 288 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 72/276 (26%), Positives = 111/276 (40%), Gaps = 33/276 (11%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 ++ A+VTG A IG+AI +L + G VVI AA L L + + Sbjct: 21 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHN---SAEAAVSLADELNKERSNTAV 77 Query: 76 PIQCNIRN----EEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG-------- 123 Q ++ N ++ S FG+ + LVNN + +P + Sbjct: 78 VCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVE 137 Query: 124 --WHAVLETNLTGTFYMC------KAVYSSWMKEHGGSIVNIIVPTKAGFPLAVH--SGA 173 ++ TN F + + + SIVN+ P Sbjct: 138 TQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNL-CDAMVDQPCMAFSLYNM 196 Query: 174 ARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK-R 232 + + LT+S ALE A GIR+N VAPGV A+ G+ + +K+P R Sbjct: 197 GKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAM------GEEEKDKWRRKVPLGRR 250 Query: 233 IGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLY 268 E+++ V FL+S +A +ITG + VDGG SL Sbjct: 251 EASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLV 286 >4NR0-A nrPDB Length = 273 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 50/265 (18%), Positives = 107/265 (40%), Gaps = 15/265 (5%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 G L G+ A++ G A+ I I + G+ + + ++L+ +E + + Sbjct: 2 GFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQN-DKLRGRVEEFASGWGSRPE 60 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEH-----ISSKGWHA 126 + C++ ++ ++ + + + ++ +V++ G + + +G+ Sbjct: 61 ---LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRI 117 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSL 185 + + + KA MK GS++ + + P G A+A + + L Sbjct: 118 AHDISAYSFIALAKA-GREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYL 176 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 A G R+N V+ G I + A + + + ++ P +R EEV + F Sbjct: 177 AGSLGAEGTRVNAVSAGPIRTLAA--SGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAF 234 Query: 246 LLSPAASFITGQSVDVDGGRSLYTH 270 L S AS I+G+ + VDGG + Sbjct: 235 LCSDLASGISGEILYVDGGFNTTAM 259 >4RGB-A nrPDB Length = 294 Score = 182 bits (462), Expect = 2e-46, Method: Composition-based stats. Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 18/273 (6%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASR-------KLERLKSAADELQ 63 G L G+V +TG A G G++ E G+N+V + E Sbjct: 18 YGMGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEET 77 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG 123 A L ++ + ++R++ + + + ++ FG I+ ++ N G +P E +S+ Sbjct: 78 ARLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEA 137 Query: 124 WHAVLETNLTGTFYMCKAVYSSWMKE-HGGSIVNIIV-----PTKAGFPLAVHSGAARAG 177 L+ L G + + + GG+++ G ++ Sbjct: 138 LRLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLA 197 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYG-----SWGQSFFEGSFQKIPAKR 232 + L +S AL A IR+N VAP + EN +P Sbjct: 198 ITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFP 257 Query: 233 IGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265 + P +VS+ + FL+S A TG + VD G Sbjct: 258 MIEPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >4CR6-A nrPDB Length = 271 Score = 182 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 78/264 (29%), Positives = 121/264 (45%), Gaps = 24/264 (9%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA 72 PG L G+ AIVTG A GIG+A V+ L G++VV + +E Sbjct: 10 PGRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEE----------P 59 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQF---LSPAEHISSKGWHAVLE 129 IPI C++ + ++ + + G ++ LV GG +S W ++ Sbjct: 60 GAIPIACDLADRAAIDAAMADAVARLGGLDILV--AGGALKGGTGNFLDLSDADWDRYVD 117 Query: 130 TNLTGTFYMCKAVYSSWMKEHGG------SIVNI-IVPTKAGFPLAVHSGAARAGVYNLT 182 N+TGTF C+A + + G I+ I V + P A AA+ GV LT Sbjct: 118 VNMTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLT 177 Query: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSV 242 +++A++ A GI +N +APG + N G E ++ R G+PEEV++ Sbjct: 178 RAMAVDLARHGILVNMIAPGPV--DVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATA 235 Query: 243 VCFLLSPAASFITGQSVDVDGGRS 266 FL +SFITG ++ +DGG S Sbjct: 236 AVFLAEDGSSFITGSTITIDGGLS 259 >2BGM-A nrPDB Length = 278 Score = 181 bits (460), Expect = 3e-46, Method: Composition-based stats. Identities = 58/238 (24%), Positives = 103/238 (43%), Gaps = 13/238 (5%) Query: 35 VKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI-PIQCNIRNEEEVNNLVKS 93 K + G+ VVIA + + VI + C++ +E+V NLV + Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKV-------CNNIGSPDVISFVHCDVTKDEDVRNLVDT 85 Query: 94 TLDTFGKINFLVNNGGGQFLSP--AEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG 151 T+ GK++ + N G +P ++ + V++ N+ G F + K + Sbjct: 86 TIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKK 145 Query: 152 GSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTA 209 GSIV I AG ++ A + V LT SL E GIR+NCV+P ++ S Sbjct: 146 GSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLL 205 Query: 210 VENYGSWGQSFFEGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRS 266 + +G E + Q + E+V+ V +L + +++G ++ +DGG + Sbjct: 206 TDVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYT 263 >3ZV3-A nrPDB Length = 281 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 59/275 (21%), Positives = 106/275 (38%), Gaps = 21/275 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L G+VA++TGGA+G+G+A+V + G+ V + + ERL+ L + Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRE--------LEVAHGGNAV 54 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG-----WHAVLET 130 + ++R+ ++ + L FGKI+ L+ N G S A + + + Sbjct: 55 GVVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHV 114 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 N+ G + KA + + G + I A + V L + +A E A Sbjct: 115 NVKGYIHAVKACLPALVSSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELA 174 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQS------FFEGSFQKIPAKRIGVPEEVSSVVC 244 +R+N VAPG + + + + + +P R+ EE + Sbjct: 175 PH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYV 233 Query: 245 FLLSPAASF-ITGQSVDVDGGRSLYTHSYEVPDHD 278 F + S TG ++ DGG + D Sbjct: 234 FFATRGDSLPATGALLNYDGGMGVRGFLTAAGGAD 268 >2QHX-A nrPDB Length = 328 Score = 177 bits (449), Expect = 6e-45, Method: Composition-based stats. Identities = 80/302 (26%), Positives = 118/302 (39%), Gaps = 53/302 (17%) Query: 6 KGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 +G AP + VA+VTG A +G++I + L G V + R + A+ L A Sbjct: 37 RGSHMTAPTV---PVALVTGAAKRLGRSIAEGLHAEGYAVCLHY---HRSAAEANALSAT 90 Query: 66 LPPTKQARVIPIQCNIRNEEE-----------------VNNLVKSTLDTFGKINFLVNNG 108 L + I +Q ++ N LV + +G+ + LVNN Sbjct: 91 LNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNA 150 Query: 109 GGQFLSPAEHISSKGWH--------------AVLETNLTGTFYMCKA----VYSSWMKEH 150 + +P G + +N +++ KA V + K Sbjct: 151 SSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHR 210 Query: 151 GG--SIVNIIVPTKAGFP--LAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYS 206 G SI+N+ V P A+ + LT+S ALE A IR+N V PG+ Sbjct: 211 GTNYSIINM-VDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--- 266 Query: 207 QTAVENYGSWGQSFFEGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265 + +EG K+P +R EVS VV FL S A +ITG V VDGG Sbjct: 267 ---SVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGY 323 Query: 266 SL 267 SL Sbjct: 324 SL 325 >2BFA-A nrPDB Length = 288 Score = 177 bits (448), Expect = 8e-45, Method: Composition-based stats. Identities = 77/288 (26%), Positives = 113/288 (39%), Gaps = 50/288 (17%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA+VTG A +G++I + L G V + R + A+ L A L + I +Q Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHY---HRSAAEANALSATLNARRPNSAITVQA 64 Query: 80 NIRNEEE-----------------VNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK 122 ++ N LV + +G+ + LVNN + +P Sbjct: 65 DLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDED 124 Query: 123 GWH--------------AVLETNLTGTFYMCKA----VYSSWMKEHGG--SIVNIIVPTK 162 G + +N +++ KA V + K G SI+N+ V Sbjct: 125 GHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINM-VDAM 183 Query: 163 AGFP--LAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSF 220 P A+ + LT+S ALE A IR+N V PG+ + Sbjct: 184 TNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL------SVLVDDMPPAV 237 Query: 221 FEGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 +EG K+P +R EVS VV FL S A +ITG V VDGG SL Sbjct: 238 WEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >1P33-A nrPDB Length = 289 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 76/287 (26%), Positives = 114/287 (39%), Gaps = 48/287 (16%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA+VTG A +G +I + L G V + R + A L A L + I +Q Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHY---HRSAADASTLAATLNARRPNSAITVQA 65 Query: 80 NIRNEEE-----------------VNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS-- 120 ++ N + LV + +G+ + LVNN + +P Sbjct: 66 DLSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAG 125 Query: 121 ------------SKGWHAVLETNLTGTFYMCKA----VYSSWMKEHGGS--IVNIIVP-T 161 + +N +++ KA V + ++ G S IVN++ T Sbjct: 126 EGGSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMT 185 Query: 162 KAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFF 221 A+ + LT+S ALE A IR+N V+PG+ S Sbjct: 186 SQPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL------SVLPDDMPFSVQ 239 Query: 222 EGSFQKIPA-KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 E +K+P +R EEVS VV FL SP A +ITG + VDGG SL Sbjct: 240 EDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >1BDB-A nrPDB Length = 277 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 63/275 (22%), Positives = 105/275 (38%), Gaps = 21/275 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ ++TGGA+G+G+A+V + G+ V + + ERL A L V+ Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERL--------AELETDHGDNVL 54 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG-----QFLSPAEHISSKGWHAVLET 130 I ++R+ E+ + FGKI+ L+ N G + E + V Sbjct: 55 GIVGDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHI 114 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 N+ G + KA + + G I I AA+ + L + LA E A Sbjct: 115 NVKGYIHAVKACLPALVASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELA 174 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQS------FFEGSFQKIPAKRIGVPEEVSSVVC 244 +R+N V G I S + G + +P R+ EE + Sbjct: 175 PY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYV 233 Query: 245 FLLSP-AASFITGQSVDVDGGRSLYTHSYEVPDHD 278 F + A+ TG ++ DGG + +D Sbjct: 234 FFATRGDAAPATGALLNYDGGLGVRGFFSGAGGND 268 >5IZ4-A nrPDB Length = 271 Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats. Identities = 59/257 (22%), Positives = 101/257 (39%), Gaps = 13/257 (5%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V ++TG A+GIG A + G +V I + A L A+ + Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIG--NFDDSTRDAASTVEALCRDAGAQTLIFDA 73 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP---AEHISSKGWHAVLETNLTGTF 136 ++ + + + V + +I+ L+N G + P + I + V NL G + Sbjct: 74 DVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLY 133 Query: 137 YMCKAVYSSWM----KEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 M +A S+VN+ G ++ A++ V LT SLA A Sbjct: 134 QMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLAP 193 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQS-FFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 IR+N +APG++ + + + P KR+ P E++ + FL + Sbjct: 194 H-IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL-TAH 251 Query: 251 ASFITGQSVDVDGGRSL 267 A ITGQ + + G L Sbjct: 252 APAITGQVIAAENGLLL 268 >1ENP-A nrPDB Length = 312 Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats. Identities = 67/296 (22%), Positives = 118/296 (39%), Gaps = 36/296 (12%) Query: 13 PGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIAS---------RKLERLKSAADE 61 P L+G+ A + G A G G A+ K L G+ +++ + L R K Sbjct: 13 PIDLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSR 72 Query: 62 LQANLPPTKQARVIPIQCNIRNEEEV------------------NNLVKSTLDTFGKINF 103 + + + +V P+ N E+V + FG I+ Sbjct: 73 VLPDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDI 132 Query: 104 LVNN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPT 161 LV++ G + P S KG+ A + + F + + M G SI + + Sbjct: 133 LVHSLANGPEVSKPLLETSRKGYLAAISASSYS-FVSLLSHFLPIMNPGGASISLTYIAS 191 Query: 162 KAGFPLAVH-SGAARAGVYNLTKSLALEWACS-GIRINCVAPGVIYSQTAVENYGSWGQS 219 + P +A+A + + T+ LA E IR+N ++ G + S+ A + + Sbjct: 192 ERIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAA--KAIGFIDT 249 Query: 220 FFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVP 275 E S+ P ++ +EV + FL+SP AS ITG ++ VD G + + + P Sbjct: 250 MIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLNSMGVALDSP 305 >4J3F-A nrPDB Length = 280 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 54/265 (20%), Positives = 104/265 (39%), Gaps = 18/265 (6%) Query: 14 GLLQGQVAIVTG--GATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 G L G+ ++TG I I K + G+ + K ++L A P Sbjct: 22 GFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQ--FKDRVEKLCAEFNP--- 76 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS-----PAEHISSKGWHA 126 + C++ +++E+ +L + ++ +V++ + ++ +G+ Sbjct: 77 --AAVLPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSI 134 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSL 185 + + + K S MK S+V + + + P G A+A + + Sbjct: 135 AHDISAYSFAALAKE-GRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYT 193 Query: 186 ALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCF 245 AL GI++N V+ G I + A + S + + + P K+ EV + V F Sbjct: 194 ALALGEDGIKVNAVSAGPIKTLAA--SGISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAF 251 Query: 246 LLSPAASFITGQSVDVDGGRSLYTH 270 L S A+ ITG+ V VD G + Sbjct: 252 LCSDMATGITGEVVHVDAGYHCVSM 276 >2GDZ-A nrPDB Length = 267 Score = 173 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 58/257 (22%), Positives = 106/257 (41%), Gaps = 23/257 (8%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 ++ G+VA+VTG A GIG+A + LL G+ V + LE L P + Sbjct: 4 MVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQ---KT 60 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 + IQC++ +++++ + + +D FG+++ LVNN G + K W L+ NL Sbjct: 61 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVS 112 Query: 135 TFYMCKAVYSSWMKEH---GGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKS--LALE 188 K++ GG I+N+ A++ G+ T+S LA Sbjct: 113 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 172 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQ----SFFEGSFQKIPAKRIGVPEEVSSVVC 244 SG+R+N + PG + + + + I I P +++ + Sbjct: 173 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 232 Query: 245 FLLSPAASFITGQSVDV 261 L+ A + G + + Sbjct: 233 TLIEDDA--LNGAIMKI 247 >5I9N-A nrPDB Length = 276 Score = 173 bits (440), Expect = 7e-44, Method: Composition-based stats. Identities = 50/260 (19%), Positives = 100/260 (38%), Gaps = 16/260 (6%) Query: 14 GLLQGQVAIVTG--GATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 G L G+ ++TG I I K G+ + +R K E A Sbjct: 2 GFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVG-DRFKDRITEFAAEFGSE-- 58 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-----GQFLSPAEHISSKGWHA 126 + C++ ++ +++ L S + ++ LV++ G + ++ + + Sbjct: 59 ---LVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRI 115 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLA 186 + + + KA + + + + + P G A+A + + LA Sbjct: 116 AHDISAYSFPALAKAALP-MLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLA 174 Query: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 + G+R+N ++ G I + A S+G+ + P KR E+V + FL Sbjct: 175 VSLGAKGVRVNAISAGPIKT-LAASGIKSFGK-ILDFVESNSPLKRNVTIEQVGNAGAFL 232 Query: 247 LSPAASFITGQSVDVDGGRS 266 LS AS +T + + VD G + Sbjct: 233 LSDLASGVTAEVMHVDSGFN 252 >4NK4-A nrPDB Length = 301 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 55/289 (19%), Positives = 118/289 (40%), Gaps = 28/289 (9%) Query: 1 MASWAKGRSY-LAPGLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKL---ER 54 MAS G+ +L+G+ ++ G A I I K L G+ + + + +R Sbjct: 23 MASMTGGQQMGRMINILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKR 82 Query: 55 LKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG---- 110 LK A + ++ I CN+ + ++ L + + + ++F+V++ Sbjct: 83 LKPLALTVDSDF---------MIPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKN 133 Query: 111 QFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVP-TKAGFPLAV 169 + P + S + + + + + HGG+++ + + P Sbjct: 134 ELRGPYYNTSRDNFIQTMLVSCFSFTEIVRRAAQLM--PHGGAMITLTYGGSMRVVPNYN 191 Query: 170 HSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP 229 A++ + + TK LA ++ IRIN ++ G + + S G+ S + P Sbjct: 192 AMAPAKSALESSTKYLACDYGGMNIRINAISAGPVRTLAGASI--SNGRDIAAWSKENSP 249 Query: 230 AKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHD 278 KR E++ + +LLS ++ +TG+ VD G ++ +P ++ Sbjct: 250 LKRTVSLEDIGNSALYLLSYLSNGVTGEIHYVDCGYNIVA----MPSYN 294 >3RKU-A nrPDB Length = 287 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 59/247 (23%), Positives = 114/247 (46%), Gaps = 14/247 (5%) Query: 4 WAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAAD 60 ++GR A L + ++TG + GIGKA E LE +++A+R+LE+L+ Sbjct: 21 MSQGRK--AAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKK 78 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP-AEHI 119 + P A+V Q +I E++ +++ F I+ LVNN G S I Sbjct: 79 TIDQEFP---NAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQI 135 Query: 120 SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGV 178 +++ V +TN+T + +AV + ++ G IVN+ + + +P A++ V Sbjct: 136 ATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAV 195 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 T SL E + IR+ +APG++ ++ ++ Y + P + ++ Sbjct: 196 GAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPL----MADD 251 Query: 239 VSSVVCF 245 V+ ++ + Sbjct: 252 VADLIVY 258 >4DA9-A nrPDB Length = 280 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 71/270 (26%), Positives = 117/270 (43%), Gaps = 18/270 (6%) Query: 8 RSYLAPGLLQGQ---VAIVTGGATGIGKAIVKELLELGSNVVIASR-KLERLKSAADELQ 63 + ++ + VAIVTGG GIG I + L G ++ I E + EL Sbjct: 16 ENLYFQSMMTQKARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELS 75 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFL--SPAEHISS 121 ARVI ++ ++ + V + + FG+I+ LVNN G + + Sbjct: 76 GL-----GARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKP 130 Query: 122 KGWHAVLETNLTGTFYMCKAVYSSWMKEH---GGSIVNI-IVPTKAGFPLAVHSGAARAG 177 + + ++ NL GT + +AV + + SI+NI V P + ++AG Sbjct: 131 ENFDTIVGVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAG 190 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPE 237 + ++ LAL A +GI + V PG+I S G + G +P +R G PE Sbjct: 191 LAAFSQGLALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGL---VPMRRWGEPE 247 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 ++ ++V L F TG + DGG S+ Sbjct: 248 DIGNIVAGLAGGQFGFATGSVIQADGGLSI 277 >2O23-A nrPDB Length = 265 Score = 170 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 58/266 (21%), Positives = 114/266 (42%), Gaps = 28/266 (10%) Query: 12 APGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 A ++G VA++TGGA+G+G A + L+ G++ V+ ++ A +L Sbjct: 6 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL--------G 57 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI------SSKGWH 125 + ++ +E++V + FG+++ VN G S ++ + + + Sbjct: 58 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 117 Query: 126 AVLETNLTGTFYMCKAVYSSWMKE------HGGSIVNI-IVPTKAGFPLAVHSGAARAGV 178 VL+ NL GTF + + V + G I+N V G A++ G+ Sbjct: 118 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 177 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK-RIGVPE 237 +T +A + A GIR+ +APG+ + + ++P R+G P Sbjct: 178 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTS----LPEKVCNFLASQVPFPSRLGDPA 233 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDG 263 E + +V ++ F+ G+ + +DG Sbjct: 234 EYAHLVQAII--ENPFLNGEVIRLDG 257 >2NWQ-A nrPDB Length = 272 Score = 170 bits (430), Expect = 9e-43, Method: Composition-based stats. Identities = 55/234 (23%), Positives = 110/234 (47%), Gaps = 13/234 (5%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +TG +G G+A + E G ++V+ R+ ERL++ A EL A RV+P+ ++ Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAK------TRVLPLTLDV 78 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQF-LSPAEHISSKGWHAVLETNLTGTFYMCK 140 R+ ++ V + + F + L+NN G PA+ W +++TN+ G Y + Sbjct: 79 RDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTR 138 Query: 141 AVYSSWMKEHGG-SIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 + + G SIVN+ V K +P + G +A V + +L + +G+R+ Sbjct: 139 LLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTN 198 Query: 199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 + PG+ S+ ++ +G + + P PE+++ + ++++ A Sbjct: 199 LEPGLCESEFSLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFWIMNQPAH 248 >4GKB-A nrPDB Length = 258 Score = 168 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 71/255 (27%), Positives = 109/255 (42%), Gaps = 12/255 (4%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQ +V IVTGGA+GIG AI L E + V+ +R A D + +Q R Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARH------APDGAFLDALAQRQPRAT 58 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + ++++ + + V T+ TFG+++ LVNN G + A LE NL Sbjct: 59 YLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVN-DGIGLDAGRDAFVASLERNLIHY 117 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 + M G+IVNI G A++ LT+ A+ G+ Sbjct: 118 YAMAHYCVPHLKATR-GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGV 176 Query: 195 RINCVAPGVIYSQTAVENYG--SWGQSFFEGSFQKIPAK-RIGVPEEVSSVVCFLLSPAA 251 R+N V P + + ++ K+P R P+E++ FLLSP A Sbjct: 177 RVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRA 236 Query: 252 SFITGQSVDVDGGRS 266 S TG+ + VDGG + Sbjct: 237 SHTTGEWLFVDGGYT 251 >4Q9N-A nrPDB Length = 298 Score = 168 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 67/292 (22%), Positives = 116/292 (39%), Gaps = 36/292 (12%) Query: 16 LQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIA---------SRKLERLKSAADELQA 64 L G++A + G G G I K L E G+ +++ S+ LE K A + Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 65 NLPPTKQARVIPIQCNIRNEEE------------------VNNLVKSTLDTFGKINFLVN 106 N A++ P+ + E+ V+ +V+ FG I+ LV+ Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 107 NGG--GQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAG 164 + + P S KG+ A L T+ F + + M +I + + Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYS-FISLLSHFGPIMNAGASTISLTYLASMRA 184 Query: 165 FPLAVH-SGAARAGVYNLTKSLALEWACS-GIRINCVAPGVIYSQTAVENYGSWGQSFFE 222 P AA+A + + TK LA E G+R+N ++ G + S+ + + + Sbjct: 185 VPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAG--KAIGFIERMVD 242 Query: 223 GSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEV 274 P E+V + FL+SP AS ITG+++ VD G ++ E+ Sbjct: 243 YYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGANVMGIGPEM 294 >2O2S-A nrPDB Length = 315 Score = 167 bits (424), Expect = 4e-42, Method: Composition-based stats. Identities = 68/299 (22%), Positives = 114/299 (38%), Gaps = 40/299 (13%) Query: 13 PGLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIAS---------RKLERLKSAADE 61 P L+GQ A V G A G G AI K L G+ V + + + L+ + D Sbjct: 4 PIDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDR 63 Query: 62 LQANLPPTKQARVIPIQCNIRNEEEVNNLVK------------------STLDTFGKINF 103 + + A V P+ E+V +K G I+ Sbjct: 64 KLPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDI 123 Query: 104 LVNN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIV-P 160 LV++ G + P S KG+ A + + + GGS V + Sbjct: 124 LVHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM--NEGGSAVTLSYLA 181 Query: 161 TKAGFPLAVH-SGAARAGVYNLTKSLALEWA-CSGIRINCVAPGVIYSQTAVENYGSWGQ 218 + P +A+A + + T++LA E G+R+N ++ G + S+ A S + Sbjct: 182 AERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEK 241 Query: 219 SFFEG----SFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYE 273 SF + S+ P +R ++V FLLSP A ++G ++ VD G + + Sbjct: 242 SFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQAVD 300 >3PXX-A nrPDB Length = 287 Score = 167 bits (423), Expect = 5e-42, Method: Composition-based stats. Identities = 61/285 (21%), Positives = 107/285 (37%), Gaps = 36/285 (12%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS------RKLERLKSAADELQANLP 67 G +Q +V +VTGGA G G++ +L E G+++++ L ++ D +A L Sbjct: 6 GRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLE 65 Query: 68 PTKQAR-VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA 126 K R + ++R+ V+ + + + FGK++ +V N G L H+ + + Sbjct: 66 VEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGA--HLPVQAFAD 123 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPT------------KAGFPLAVHSGAA 174 + + G A G SI+ P A Sbjct: 124 AFDVDFVGVINTVHAALPYL--TSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYA 181 Query: 175 RAGVYNLTKSLALEWACSGIRINCVAPGVIYSQT--AVENYGSWGQSFFEGS-------- 224 + V + T LA + A IR N + P + + + Y + S Sbjct: 182 KQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAF 241 Query: 225 --FQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 Q +P ++S+ VCFL S + ++TG VD G L Sbjct: 242 PAMQAMPTP-YVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >1E3W-A nrPDB Length = 261 Score = 167 bits (423), Expect = 6e-42, Method: Composition-based stats. Identities = 60/263 (22%), Positives = 110/263 (41%), Gaps = 28/263 (10%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 ++G VA++TGGA+G+G + K L+ G+ V+ ++ A +L Sbjct: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL--------GGNC 58 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI------SSKGWHAVL 128 I N+ +E+EV + + FG+I+ VN G H + + + V+ Sbjct: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 Query: 129 ETNLTGTFYMCKAVYSSWMKE------HGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNL 181 NL GTF + + V + G I+N V G A++ G+ + Sbjct: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 Query: 182 TKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK-RIGVPEEVS 240 T +A + A GIR+ +APG+ + + ++P R+G P E + Sbjct: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTT----LPDTVRNFLASQVPFPSRLGDPAEYA 234 Query: 241 SVVCFLLSPAASFITGQSVDVDG 263 +V ++ F+ G+ + +DG Sbjct: 235 HLVQMVI--ENPFLNGEVIRLDG 255 >3OML-A nrPDB Length = 613 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 48/244 (19%), Positives = 96/244 (39%), Gaps = 20/244 (8%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G+VA+VTG G+G+ E G+ VV+ A + A++ + + Sbjct: 18 DGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGG 77 Query: 77 -IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + + + ++++ + FG+++ LVNN G S + W+ V + +L G+ Sbjct: 78 EAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGS 137 Query: 136 FYMCKAVYSSWMKEHGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 F +A + K++ G I+ G V+ AA+ G+ L ++A+E A + + Sbjct: 138 FKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNV 197 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL----LSPA 250 N + P S+ + + ++ VV +L Sbjct: 198 LCNVIVPTA-ASRMTEGILPDILFNELKPKL-------------IAPVVAYLCHESCEDN 243 Query: 251 ASFI 254 S+I Sbjct: 244 GSYI 247 >2NTV-A nrPDB Length = 268 Score = 154 bits (389), Expect = 4e-38, Method: Composition-based stats. Identities = 66/273 (24%), Positives = 108/273 (39%), Gaps = 30/273 (10%) Query: 14 GLLQGQVAIVTGG--ATGIGKAIVKELLELGSNVVIASRKLERL-KSAADELQANLPPTK 70 GLL+G+ +V+G + I I K E G+ +V+ RL + AD L P Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPL-- 59 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFG---KINFLVNNGG-----GQFLSPAEHISSK 122 I+ +++NEE + L + G K++ +V++ G G + + Sbjct: 60 ------IELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYE 113 Query: 123 GWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLT 182 + + + KA+ + GGSIV + P A++ + ++ Sbjct: 114 DVSKGIHISTYSYASLAKALL--LIMNSGGSIVGMDFDPTRAMPAYNWMTVAKSALESVN 171 Query: 183 KSLALEWACSGIRINCVAPGVIYSQTAV--------ENYGSWGQSFFEGSFQKIPAKR-I 233 + +A E G+R N VA G I + E G+ Q EG Q+ P + Sbjct: 172 RFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNM 231 Query: 234 GVPEEVSSVVCFLLSPAASFITGQSVDVDGGRS 266 P V+ VC LLS TG + DGG S Sbjct: 232 KDPTPVAKTVCALLSEWLPATTGSIIYADGGAS 264 >4OYR-A nrPDB Length = 289 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 61/272 (22%), Positives = 104/272 (38%), Gaps = 28/272 (10%) Query: 14 GLLQGQVAIVTGG--ATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 GLL G+ +V+G + I I + E G+ +V+ R L + Sbjct: 23 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLR-------LIQRITDRLP 75 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFG---KINFLVNNGG-----GQFLSPAEHISSKG 123 A+ ++ +++NEE + +L + G K++ +V++ G G ++P Sbjct: 76 AKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYAD 135 Query: 124 WHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTK 183 + + M KA+ GGSIV + P A++ + ++ + Sbjct: 136 VSKGIHISAYSYASMAKALLPIM--NPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNR 193 Query: 184 SLALEWACSGIRINCVAPGVIYSQTAV--------ENYGSWGQSFFEGSFQKIPAKR-IG 234 +A E G+R N VA G I + E G+ Q EG Q+ P + Sbjct: 194 FVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMK 253 Query: 235 VPEEVSSVVCFLLSPAASFITGQSVDVDGGRS 266 V+ VC LLS TG + DGG Sbjct: 254 DATPVAKTVCALLSDWLPATTGDIIYADGGAH 285 >2PTG-A nrPDB Length = 319 Score = 151 bits (383), Expect = 3e-37, Method: Composition-based stats. Identities = 61/311 (19%), Positives = 117/311 (37%), Gaps = 51/311 (16%) Query: 13 PGLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIAS--------------------- 49 P L+G+ A V G A G G AI K L G+ V++ + Sbjct: 4 PVDLRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDS 63 Query: 50 -RKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEV------------------NNL 90 E A E ++ P+ ++V + + Sbjct: 64 FYAQEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEV 123 Query: 91 VKSTLDTFGKINFLVNN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMK 148 ++ G+I+ LV++ G + P S KG+ A + ++ + + MK Sbjct: 124 AEAVRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLP-LMK 182 Query: 149 EHGGSIVNIIVPTKAGFPLAVH-SGAARAGVYNLTKSLALEWAC-SGIRINCVAPGVIYS 206 E G ++ + ++ P +A+A + + ++LA E +R+NC++ G + S Sbjct: 183 EGGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKS 242 Query: 207 QTAVENYGSWGQSFFE----GSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVD 262 + A + ++F + S P ++ ++V FLLSP A +TG ++ VD Sbjct: 243 RAASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVD 302 Query: 263 GGRSLYTHSYE 273 G + + Sbjct: 303 NGLHAMGQALD 313 >3PPI-A nrPDB Length = 281 Score = 150 bits (380), Expect = 6e-37, Method: Composition-based stats. Identities = 71/269 (26%), Positives = 120/269 (44%), Gaps = 29/269 (10%) Query: 9 SYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 S + +G AIV+GGA G+G+A V+ L G VVIA E+ K+ ADEL Sbjct: 21 SMVTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADEL------ 74 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS------PAEHISSK 122 R + N+ +E+ V +++ + G++ + V GG ++ Sbjct: 75 --GNRAEFVSTNVTSEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMG 131 Query: 123 GWHAVLETNLTGTFYMCKAVYSSWMK-------EHGGSIVNIIVPTKAGFPLAVHSGAAR 175 G+ ++ L GT+ + + V +S E G ++ + G AA+ Sbjct: 132 GFTKTIDLYLNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAK 191 Query: 176 AGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIG 234 AGV LT + A + + +GIR+N +APG + + G+ IP KR+G Sbjct: 192 AGVIGLTIAAARDLSSAGIRVNTIAPGTMKTPIMESV----GEEALAKFAANIPFPKRLG 247 Query: 235 VPEEVSSVVCFLLSPAASFITGQSVDVDG 263 P+E + FLL+ +I G+ + +DG Sbjct: 248 TPDEFADAAAFLLT--NGYINGEVMRLDG 274 >1A27-A nrPDB Length = 289 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 52/246 (21%), Positives = 93/246 (37%), Gaps = 27/246 (10%) Query: 20 VAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 V ++TG ++GIG + L V R L+ + +A P + Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACP--PGSLET 61 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 +Q ++R+ + V + + G+++ LV N G L P E + +VL+ N+ GT Sbjct: 62 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 119 Query: 137 YMCKAVYSSWMKEHGGSI-VNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 M +A + G + V V G P A++ + L +SLA+ G+ Sbjct: 120 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 179 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV---------------PEEVS 240 ++ + G +++ + GS + R PEEV+ Sbjct: 180 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFH--RFYQYLAHSKQVFREAAQNPEEVA 237 Query: 241 SVVCFL 246 V FL Sbjct: 238 EV--FL 241 >6CGE-A nrPDB Length = 328 Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats. Identities = 52/246 (21%), Positives = 93/246 (37%), Gaps = 27/246 (10%) Query: 20 VAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 V ++TG ++GIG + L V R L+ + +A P + Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACP--PGSLET 62 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 +Q ++R+ + V + + G+++ LV N G L P E + +VL+ N+ GT Sbjct: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 Query: 137 YMCKAVYSSWMKEHGGSI-VNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIR 195 M +A + G + V V G P A++ + L +SLA+ G+ Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 Query: 196 INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV---------------PEEVS 240 ++ + G +++ + GS + R PEEV+ Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFH--RFYQYLAHSKQVFREAAQNPEEVA 238 Query: 241 SVVCFL 246 V FL Sbjct: 239 EV--FL 242 >3DWF-A nrPDB Length = 276 Score = 146 bits (370), Expect = 8e-36, Method: Composition-based stats. Identities = 44/203 (21%), Positives = 81/203 (39%), Gaps = 6/203 (2%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 P +LQG+ IVTG + GIG+ I L ++G++VV+ +R K A ++ A Sbjct: 4 FRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARS----KEALQKVVARCLELG 59 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 A I ++ + V + G ++ L+ N H +E Sbjct: 60 AASAHYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEV 119 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWA 190 N + A M+ G V V K +PL A++ + +L E+ Sbjct: 120 NFHSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFL 179 Query: 191 CSGIRINCVAP--GVIYSQTAVE 211 + + ++ G+I ++TA++ Sbjct: 180 VNKVNVSITLCILGLIDTETAIK 202 >2PD3-A nrPDB Length = 275 Score = 146 bits (369), Expect = 1e-35, Method: Composition-based stats. Identities = 46/275 (16%), Positives = 103/275 (37%), Gaps = 23/275 (8%) Query: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKL---ERLKSAADELQANLPP 68 G L+G+ ++ G A I I + G+ + +R++ A EL + Sbjct: 2 GFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSP--- 58 Query: 69 TKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAE----HISSKGW 124 + ++ EE +L S G ++F+V++ E S + Sbjct: 59 ------YVYELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAF 112 Query: 125 HAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTK 183 + +E ++ + + +G S++ + + G A+A + + + Sbjct: 113 NTAMEISVYSLIELTNTLKPLL--NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVR 170 Query: 184 SLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVV 243 LA++ IR+N ++ G I + + + + + + P ++ EEV + Sbjct: 171 YLAVDLGKHHIRVNALSAGPIRT--LASSGIADFRMILKWNEINAPLRKNVSLEEVGNAG 228 Query: 244 CFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHD 278 +LLS +S ++G+ VD G + + Sbjct: 229 MYLLSSLSSGVSGEVHFVDAGYHVMGMGAVEEKDN 263 >4DRY-A nrPDB Length = 281 Score = 145 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 62/248 (25%), Positives = 111/248 (44%), Gaps = 17/248 (6%) Query: 8 RSYLAPG--LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 +S +A G +G++A+VTGG TG+G+ I + L G +VVI R+ + L +AA E+ Sbjct: 21 QSMMAQGKGSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGR 80 Query: 66 LPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQF-LSPAEHISSKGW 124 V + C++ + ++V L + F +++ LVNN G P E ++ + W Sbjct: 81 ----TGNIVRAVVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQW 136 Query: 125 HAVLETNLTGTFYMCKAVYSSWMKE--HGGSIV-NIIVPTKAGFPLAVHSGAARAGVYNL 181 + ++ NLTG F + + + GG I+ N + + P + A + + L Sbjct: 137 NGIVAANLTGAFLCTQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGL 196 Query: 182 TKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQ-KIPAKRIGVPEEVS 240 TKS AL+ I + G + Q+ E + + IP E ++ Sbjct: 197 TKSTALDGRMHDIACGQIDIGNAATDMTARMSTGVLQANGEVAAEPTIPI------EHIA 250 Query: 241 SVVCFLLS 248 V ++ S Sbjct: 251 EAVVYMAS 258 >4HBG-A nrPDB Length = 286 Score = 143 bits (361), Expect = 8e-35, Method: Composition-based stats. Identities = 57/273 (20%), Positives = 91/273 (33%), Gaps = 44/273 (16%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VAIVTG GIGKAI ++L + G + +I E ++ A + R I Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 80 NIR------------------NEEEVNNLVKSTLDTFGK---------INFLVNNGGGQF 112 + + + + + D K +N L+N G Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 113 LSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEH------GGS-----IVNIIV-- 159 S + ++ ++ N M MK G IVNI Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 160 -PTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQ 218 K P A++A + T+ LA E IR ++PG++ ++N + Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 Query: 219 SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 E + I A P E++ V L S A Sbjct: 246 EMLE---RTIGASGTSAPAEIAEEVWSLYSRTA 275 >5PGZ-A nrPDB Length = 276 Score = 137 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 43/206 (20%), Positives = 81/206 (39%), Gaps = 8/206 (3%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 P +LQG+ IVTG + GIG+ + L ++G++VV+ +R E L ++ + Sbjct: 11 FRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGL----QKVVSRCLELG 66 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 A I + + + G ++ L+ N Q H V+E Sbjct: 67 AASAHYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEV 126 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 N M A +K+ GSI I K P+ A++ + ++ E Sbjct: 127 NFLSYVVMSTAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 Query: 190 ACSGIRINCVAP--GVIYSQTAVENY 213 + + ++ G+I ++TA++ Sbjct: 186 YITKVNVSITLCVLGLIDTETAMKEI 211 >5ILO-A nrPDB Length = 271 Score = 135 bits (340), Expect = 3e-32, Method: Composition-based stats. Identities = 55/201 (27%), Positives = 85/201 (42%), Gaps = 20/201 (9%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGS-NVVIASRKLERLKSAADELQANLPPTKQAR 73 +G+ A+VTGGA GIG + K+LL G+ V I L+ +E Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIID-----LQDNLEEFVKLRAAHPTQS 66 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 V+ I+ ++ N++ V + TFG I+ +VN G + K L NL Sbjct: 67 VMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGI--------FNDKDVQRTLLVNLG 118 Query: 134 GTFYMCKAVYSSWMKEHGGS---IVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALE- 188 G + K++GG +VN+ V + GA +AG+ N T+ LA E Sbjct: 119 GIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEK 178 Query: 189 -WACSGIRINCVAPGVIYSQT 208 + SGI+ V PG + Sbjct: 179 YYQRSGIKFVTVCPGATMTDM 199 >3F4B-A nrPDB Length = 323 Score = 135 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 62/307 (20%), Positives = 115/307 (37%), Gaps = 58/307 (18%) Query: 17 QGQVAIVTGG--ATGIGKAIVKELLELGSNVV---------IASRKLERLKSAADEL--Q 63 + ++ + G + G G I KEL + V+ I + LE K D + Sbjct: 6 ENEICFIAGVGDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINN 65 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNN------------------LVKSTLDTFGKINFLV 105 N + V+P+ N ++++ + + +GKI+ LV Sbjct: 66 DNSKRMQILDVLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLV 125 Query: 106 NN--GGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIV-PTK 162 ++ G + S G+ + + +CK GGS+V++ ++ Sbjct: 126 HSLANGREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM--NSGGSVVSLTYQASQ 183 Query: 163 AGFPLAVH-SGAARAGVYNLTKSLALEWA-CSGIRINCVAPGVIYSQTAVENYG------ 214 P +A+A + + T+ LA IRIN ++ G + S+ A Sbjct: 184 KVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQK 243 Query: 215 --------------SWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVD 260 S+ + S + P K+ + +V SV FLLS +S +TGQ++ Sbjct: 244 NNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIY 303 Query: 261 VDGGRSL 267 VD G ++ Sbjct: 304 VDNGLNI 310 >2HRB-A nrPDB Length = 274 Score = 128 bits (322), Expect = 3e-30, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 89/252 (35%), Gaps = 56/252 (22%) Query: 19 QVAIVTGGATGIGKAIVKELLELGS-NVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 +VA+VTG GIG AI +EL S +VV+ +R + R ++A +LQA + Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPR-----FH 57 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 Q +I + + + L +G +N LVNN F S L+TN T Sbjct: 58 QLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRN 117 Query: 138 MCKAVYSSWMKEHGGSIVNII--------------------------------------- 158 MC + + G +VNI Sbjct: 118 MCNELLPIM--KPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVED 175 Query: 159 ----VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS----GIRINCVAPGVIYSQTAV 210 V + G+P G ++ GV L++ LA I +N PG + + Sbjct: 176 TKNEVHEREGWPN-SPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDG 234 Query: 211 ENYGSWGQSFFE 222 ++ + E Sbjct: 235 KDSIRTVEEGAE 246 >5L51-A nrPDB Length = 324 Score = 125 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 51/288 (17%), Positives = 87/288 (30%), Gaps = 80/288 (27%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 + A+VTG GIG I K+L G V++ASR +R A + L L V+ Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ------------------------- 111 Q ++ + V LV FG ++ LVNN G Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSG 133 Query: 112 -------FLSPAEHI--SSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIV--- 159 + + + +ETN G+ + +A+ + IVN+ Sbjct: 134 AAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLS 193 Query: 160 --------------PTKAGF---------------------------PLAVHSGAARAGV 178 ++ G P ++A + Sbjct: 194 SLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAAL 253 Query: 179 YNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQ 226 T+ +A ++ RIN V PG + + + E + Sbjct: 254 NAYTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQFTDAEAAEAPVK 299 >3U9L-A nrPDB Length = 324 Score = 123 bits (310), Expect = 7e-29, Method: Composition-based stats. Identities = 45/240 (18%), Positives = 100/240 (41%), Gaps = 5/240 (2%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + ++ ++TG ++G G+ + L G V + R + ++ E A + Sbjct: 3 MSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLR 62 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ +++++ V+ + + G+I+ L++N G PAE + + + + + N+ T Sbjct: 63 TLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVLST 122 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGF--PLAVHSGAARAGVYNLTKSLALEWACSG 193 + +A ++ G ++ I + AG P AA+A + + A E + G Sbjct: 123 QRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRWG 182 Query: 194 IRINCVAPGVIYSQTA-VENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 I + + PG S T + G + ++ P +G EE+ ++ P A Sbjct: 183 IETSIIVPGAFTSGTNHFAHSGVPDDHARQAEYEAGPNAGLG--EEIKKAFAAIVPPDAD 240 >3KZV-A nrPDB Length = 254 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 45/203 (22%), Positives = 82/203 (40%), Gaps = 9/203 (4%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 G+V +VTG + GIGK+IV L L + V+ + R ++ +L+ R + Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVV--YGVARSEAPLKKLKEKY----GDRFFYV 55 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG-QFLSPAEHISSKGWHAVLETNLTGTF 136 +I + + LV + + GKI+ LV N G + + I W + + N Sbjct: 56 VGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIV 115 Query: 137 YMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 + K +G + F G+++A + + +LA E ++ Sbjct: 116 SLVGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKA 173 Query: 197 NCVAPGVIYSQTAVENYGSWGQS 219 VAPG++ + V + G S Sbjct: 174 IAVAPGIVDTDMQVNIRENVGPS 196 >3E9N-A nrPDB Length = 245 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 55/248 (22%), Positives = 95/248 (38%), Gaps = 23/248 (9%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 L+ ++A+VTG G+G IVK+L V R E L + A+ V Sbjct: 2 SLKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAE----------IEGV 50 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 PI+ +I E V + ++ LV+ + E S WHA L+ N+ Sbjct: 51 EPIESDIVKEVLEEGGVDKLKN-LDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIV 109 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 + + + + G I P A++ + L + E A +GI Sbjct: 110 PAELSRQLLPALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGI 169 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 R++ V+PG + S G +F + P+E+++ + F++ A Sbjct: 170 RVSTVSPGPTNTPMLQGLMDSQGTNFRPEIY--------IEPKEIANAIRFVI--DAGET 219 Query: 255 TGQSVDVD 262 T Q +VD Sbjct: 220 T-QITNVD 226 >2O2Y-A nrPDB Length = 349 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 58/327 (17%), Positives = 108/327 (33%), Gaps = 73/327 (22%) Query: 25 GGATGIGKAIVKELLELGSNVV---------IASRKLERLKSAADELQANLPPTKQARVI 75 G G G I KEL + ++ I + + K D + ++ Sbjct: 23 GDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDML 82 Query: 76 PIQCNIRNEEEVNN------------------LVKSTLDTFGKINFLVNN--GGGQFLSP 115 P + +++ + +GKIN LV++ + Sbjct: 83 PFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKD 142 Query: 116 AEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVH-SGAA 174 + S KG+ L + +CK + MK I ++ P +A Sbjct: 143 LLNTSRKGYLDALSKSSYSLISLCKYFVN-IMKPQSSIISLTYHASQKVVPGYGGGMSSA 201 Query: 175 RAGVYNLTKSLALEWAC-SGIRINCVAPGVIYSQTA------------------------ 209 +A + + T+ LA IRIN ++ G + S+ A Sbjct: 202 KAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHD 261 Query: 210 ----VENYGSWGQS-------------FFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAAS 252 + N G + E S + P ++ + ++ SV FLLS + Sbjct: 262 VHNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESR 321 Query: 253 FITGQSVDVDGGRSLYTHSYEVPDHDN 279 ITGQ++ VD G ++ ++ ++N Sbjct: 322 AITGQTIYVDNGLNIMFLPDDIYRNEN 348 >1N5D-A nrPDB Length = 288 Score = 117 bits (294), Expect = 5e-27, Method: Composition-based stats. Identities = 47/247 (19%), Positives = 82/247 (33%), Gaps = 54/247 (21%) Query: 19 QVAIVTGGATGIGKAIVKELLELGS-NVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 +VA+VTG GIG AIV++L + +VV+ +R + R ++A +LQA + Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPR-----FH 59 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 Q +I + + + L +G ++ LVNN F ++TN GT Sbjct: 60 QLDIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRN 119 Query: 138 MCKAVYSSWMKEHGGSIVNIIVP-TKAGFP------------------------------ 166 +C + + G +VN+ Sbjct: 120 VCTELLPLIKPQ--GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVED 177 Query: 167 -----------LAVHSGAARAGVYNLTKSLALEW----ACSGIRINCVAPGVIYSQTAVE 211 G + GV L++ A + A I +N PG + + Sbjct: 178 TKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDMGGP 237 Query: 212 NYGSWGQ 218 + Sbjct: 238 KAPKSPE 244 >3UCF-A nrPDB Length = 223 Score = 116 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 96/250 (38%), Gaps = 37/250 (14%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V +V GG +GIG + K+L + V +ASR+ Sbjct: 8 VYVVLGGTSGIGAELAKQLESEHTIVHVASRQ-------------------------TGL 42 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS-PAEHISSKGWHAVLETNLTGTFYM 138 +I +E+ V + ++ G + L+ G + + +T G Sbjct: 43 DISDEKSVYHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLA 98 Query: 139 CKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 K + GGSI + ++ A A + TK LA E A IR+N Sbjct: 99 AKHGARYL--KQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVN 154 Query: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQ 257 ++PG+ ++ + ++ + +P ++G +++ + +L + S++TG Sbjct: 155 AISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIA--MAYLFAIQNSYMTGT 212 Query: 258 SVDVDGGRSL 267 +DVDGG L Sbjct: 213 VIDVDGGALL 222 >2DKN-A nrPDB Length = 255 Score = 116 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 58/281 (20%), Positives = 96/281 (34%), Gaps = 60/281 (21%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V +TG A+GIG A+ + L G V+ R I+ Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQAD----------------------IEA 40 Query: 80 NIRNEEEVNNLVKSTLDTFGK-INFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ V + LD G ++ LV G + + V+ N G + Sbjct: 41 DLSTPGGRETAVAAVLDRCGGVLDGLVCCAGVGVTAANSGL-------VVAVNYFGVSAL 93 Query: 139 CKAVYSSWMK--EHGGSIVNIIVPTKAGFP-------------------------LAVHS 171 + + + + IV I T+ G + Sbjct: 94 LDGLAEALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAY 153 Query: 172 GAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI-PA 230 ++ V L + ++WA G+R+N VAPG + + + E + + + P Sbjct: 154 AGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLL--QASKADPRYGESTRRFVAPL 211 Query: 231 KRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHS 271 R P EV+ + FLL P ASFI G + VDGG + Sbjct: 212 GRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGMDALMRA 252 >3BHI-A nrPDB Length = 276 Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 56/251 (22%), Positives = 92/251 (36%), Gaps = 56/251 (22%) Query: 20 VAIVTGGATGIGKAIVKELLELGS-NVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 VA+VTGG GIG AIV++L L S +VV+ +R + R ++A +LQA + Q Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPR-----FHQ 60 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 +I + + + L +G ++ LVNN G F ++TN GT + Sbjct: 61 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDV 120 Query: 139 CKAVYSSWMKEHGGSIVNII---------------------------------------- 158 C + + G +VN+ Sbjct: 121 CTELLPLIKPQ--GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDT 178 Query: 159 ---VPTKAGFPLAVHSGAARAGVYNLTKSLALEWA----CSGIRINCVAPGVIYSQTAVE 211 V K G+P + G + GV L++ A + + I +N PG + + A Sbjct: 179 KKGVHQKEGWPSSA-YGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGP 237 Query: 212 NYGSWGQSFFE 222 + E Sbjct: 238 KATKSPEEGAE 248 >3O26-A nrPDB Length = 311 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 49/292 (16%), Positives = 89/292 (30%), Gaps = 82/292 (28%) Query: 11 LAPGLLQGQV-AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 P + + A+VTGG GIG I K+L G VV+ R + + A ++L+ + Sbjct: 4 TCPNTVTKRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLK----NS 59 Query: 70 KQARVIPIQCNIRNE-EEVNNLVKSTLDTFGKINFLVNNGGGQFLSP------------- 115 V+ Q ++ + +++L FGK++ LVNN G S Sbjct: 60 NHENVVFHQLDVTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIG 119 Query: 116 -----------------AEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNII 158 + + L+ N G + + + IVN+ Sbjct: 120 EDSEELVKIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVS 179 Query: 159 VPT-------------------------------------------KAGFPLA-VHSGAA 174 T G+P + Sbjct: 180 SSTGSLKYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTS 239 Query: 175 RAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQ 226 +A + T+ LA + +NCV PG++ ++ + E + Sbjct: 240 KACLNAYTRVLANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVR 289 >5LCX-A nrPDB Length = 316 Score = 106 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 48/274 (17%), Positives = 82/274 (29%), Gaps = 84/274 (30%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + A+VTG GIG I ++L E G V++ SR +R A +L L ++ R++ Q Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSEN-RLVFHQ 66 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS------SKGWHAVLE--- 129 ++ + V + FGK++ LVNN G + +S + A+ Sbjct: 67 LDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEA 126 Query: 130 ----------------------------TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPT 161 TN G + +A+ IVN+ Sbjct: 127 GAKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSF 186 Query: 162 KAGF--------------------------------------------PLAVHSGAARAG 177 + P ++A Sbjct: 187 GSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAA 246 Query: 178 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVE 211 + TK A ++ RIN + PG + Sbjct: 247 LNAYTKIAAKKYPSF--RINAICPGYAKTDITFH 278 >1B15-A nrPDB Length = 254 Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 41/217 (18%), Positives = 69/217 (31%), Gaps = 17/217 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L + I GIG +EL++ + ++E + A+ + P Sbjct: 3 LTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAE--LKAINPKVNITFH 60 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 + E L+K D ++ L+N G + + N TG Sbjct: 61 TYDVTVPVAES-KKLLKKIFDQLKTVDILINGAGI--------LDDHQIERTIAINFTGL 111 Query: 136 FYMCKAVYSSWMKEHGG---SIVNIIVPTKAGFPLAV-HSGAARAGVYNLTKSLALEWAC 191 A+ W K GG I NI T V A++A V + T SLA Sbjct: 112 VNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPI 171 Query: 192 SGIRINCVAPGVIYSQT--AVENYGSWGQSFFEGSFQ 226 +G+ + PG+ + ++ E Sbjct: 172 TGVTAYSINPGITRTPLVHTFNSWLDVEPRVAELLLS 208 >1FJH-A nrPDB Length = 257 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 53/285 (18%), Positives = 94/285 (32%), Gaps = 62/285 (21%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 + +++G ATGIG A K L G +V + + Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE----------------------VIA 40 Query: 80 NIRNEEEVNNLVKSTLDTFG-KINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ E + L ++ LV G + V+ N G + Sbjct: 41 DLSTAEGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVL-------GNVVSVNYFGATEL 93 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGFP-----------------------------LAV 169 A + K H + V I A + Sbjct: 94 MDAFLPALKKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNL 153 Query: 170 HSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP 229 ++ + + A W +G+R+N +APG ++T + G + E + +P Sbjct: 154 AYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPG--ATETPLLQAGLQDPRYGESIAKFVP 211 Query: 230 -AKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYE 273 R P E++SV+ FL+SPAAS++ G + +DGG + Sbjct: 212 PMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGIDAVMRPTQ 256 >1MG5-A nrPDB Length = 255 Score = 97.7 bits (242), Expect = 6e-21, Method: Composition-based stats. Identities = 49/219 (22%), Positives = 71/219 (32%), Gaps = 21/219 (9%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSN-VVIASRKLERLKSAADELQANLPPTKQARV 74 L + I G GIG KELL+ +VI R +A EL+A P V Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENP--AAIAELKAINPKVT---V 58 Query: 75 IPIQCNIRNE-EEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 ++ E L+K+ ++ L+N G + + N T Sbjct: 59 TFYPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGI--------LDDHQIERTIAVNYT 110 Query: 134 GTFYMCKAVYSSWMKEHGG---SIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 G A+ W K GG I NI V +A V N T SLA Sbjct: 111 GLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLA 170 Query: 190 ACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQ 226 +G+ V PG+ + ++ E Sbjct: 171 PITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLA 209 >1SNY-A nrPDB Length = 267 Score = 90.0 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 79/229 (34%), Gaps = 27/229 (11%) Query: 21 AIVTGGATGIGKAIVKELLELGS---NVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 ++TG G+G +VK LL L ++ R E+ K D + + + Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELED------LAKNHSNIHIL 77 Query: 78 QCNIRNEEEVNNLVKST--LDTFGKINFLVNNGGGQFLSP-AEHISSKGWHAVLETNLTG 134 + ++RN + + LV + +N L NN G S + S+ L+TN Sbjct: 78 EIDLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVV 137 Query: 135 TFYMCKAVYSSWMKE-----------HGGSIVNIIV--PTKAGF--PLAVHSGAARAGVY 179 + KA K +I+N+ + G +++ + Sbjct: 138 PIMLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALN 197 Query: 180 NLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI 228 TKSL+++ I + PG + + + + Q I Sbjct: 198 AATKSLSVDLYPQRIMCVSLHPGWVKTDMGGSSAPLDVPTSTGQIVQTI 246 >5TQV-A nrPDB Length = 233 Score = 81.5 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 32/218 (14%), Positives = 71/218 (32%), Gaps = 26/218 (11%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + ++ G + G+G+ V++ G NV+ +R A+L + Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDD-----------ASLAALRALGAHAHA 58 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP--AEHISSKGWHAVLETNLTGTF 136 +I E++ L +++ V G E I+S + V+ TN+ G Sbjct: 59 LDITQPEQIAALGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPM 116 Query: 137 YMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVH------SGAARAGVYNLTKSLALEWA 190 + + G V +V ++ G A++A + ++ + + Sbjct: 117 QLLPILLPLVEDARG---VLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIAS--LQ 171 Query: 191 CSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI 228 + PG + + + G + I Sbjct: 172 TRHAACISLHPGWVRTDMGGAQAALDPATSVTGMRRVI 209 >4Z3K-A nrPDB Length = 275 Score = 80.3 bits (197), Expect = 9e-16, Method: Composition-based stats. Identities = 51/254 (20%), Positives = 95/254 (37%), Gaps = 26/254 (10%) Query: 1 MASWAKGRSYLAPGLLQG----QVAIVTGGATGIGK---AIVKELLELGSNVVIASRKLE 53 M + G ++G V ++TG + G G+ ++ LL GS +V+++R E Sbjct: 1 MHHHHHHENLYFQG-MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDE 59 Query: 54 RLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLD-----TFGKINFLVNNG 108 L+ EL A RV+ + ++ E + L+ + + ++ L+NN Sbjct: 60 ALRQLEAELGAE---RSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNA 115 Query: 109 G--GQFLSPAEHISSK-GWHAVLETNLTGTFYMCKAVYSSWMKEHG--GSIVNIIVP-TK 162 G G +S + NLT + +V ++ G ++VNI Sbjct: 116 GSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCAL 175 Query: 163 AGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQT-AVENYGSWGQSFF 221 F A +A L + LALE +R+ APG + + + S Sbjct: 176 QPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMR 233 Query: 222 EGSFQKIPAKRIGV 235 +G + ++ Sbjct: 234 KGLQELKAKGKLVD 247 >4HWK-A nrPDB Length = 288 Score = 80.0 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 48/231 (20%), Positives = 89/231 (38%), Gaps = 21/231 (9%) Query: 20 VAIVTGGATGIGK---AIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 V ++TG + G G+ ++ LL GS +V+++R E L+ EL A RV+ Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAE---RSGLRVVR 92 Query: 77 IQCNIRNEEEVNNLVKSTLD-----TFGKINFLVNNGG--GQFLSPAEHISSK-GWHAVL 128 + ++ E + L+ + + ++ L+NN G G +S + Sbjct: 93 VPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYW 151 Query: 129 ETNLTGTFYMCKAVYSSWMKEHG--GSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSL 185 NLT + +V ++ G ++VNI F A +A L + L Sbjct: 152 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 211 Query: 186 ALEWACSGIRINCVAPGVIYSQT-AVENYGSWGQSFFEGSFQKIPAKRIGV 235 ALE +R+ APG + + + S +G + ++ Sbjct: 212 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 260 >1OAA-A nrPDB Length = 259 Score = 78.8 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 42/203 (20%), Positives = 79/203 (38%), Gaps = 20/203 (9%) Query: 20 VAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 V ++TG + G G+A+ +L L GS +++++R L+ +EL A P +V+ Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDL---KVVL 64 Query: 77 IQCNIRNEEEVNNLVKSTL-----DTFGKINFLVNNGGGQFLSPAEHISSKGWHAV---L 128 ++ E V L+ + + ++ L+NN ++ V Sbjct: 65 AAADLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYW 123 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGS--IVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSL 185 NLT + +++ G S +VNI + A +A L + L Sbjct: 124 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 183 Query: 186 ALEWACSGIRINCVAPGVIYSQT 208 A E +R+ APG + + Sbjct: 184 AAE--EPSVRVLSYAPGPLDNDM 204 >5WQO-A nrPDB Length = 234 Score = 78.8 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 29/214 (13%), Positives = 72/214 (33%), Gaps = 15/214 (7%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 ++ G + GIG + L+ G+ V +R+ + L R+ + + Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGL-----QALAERAGERLQAVTGD 63 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFL--SPAEHISSKGWHAVLETNLTGTFYM 138 + + + + + +I+ L+ N G I ++ + TN + Sbjct: 64 LNQHDCAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRL 121 Query: 139 CKAVYSSWMKEHGGSIVNIIVP----TKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 +A+ GG + + GA++A + +L +S E+ Sbjct: 122 ARALSGRV--SRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPF 179 Query: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI 228 + + PG + ++ ++ + G + Sbjct: 180 SLLLLHPGWVRTEMGGDSAPLSVEESAAGLVAAV 213 >3SLK-A nrPDB Length = 795 Score = 68.4 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 38/187 (20%), Positives = 69/187 (36%), Gaps = 19/187 (10%) Query: 20 VAIVTGGATGIGKAIVKELL-ELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VTGG +G + + L+ E G ++ + S A EL A L A V Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTA-YGAEVSLQA 590 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 C++ + E + ++ S D + +V+ G +E ++ + VL + G + Sbjct: 591 CDVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNL 649 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNL----------TKSLALE 188 + ++ V G + AA + + L T+SLA Sbjct: 650 L-----ELIDPDVALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLAWG 704 Query: 189 -WACSGI 194 WA G+ Sbjct: 705 PWAEHGM 711 >4LIS-A nrPDB Length = 371 Score = 64.2 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 25/178 (14%), Positives = 53/178 (29%), Gaps = 38/178 (21%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 +VTGG IG LLE G VV+A A + + + Q + Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRI----ELISGKKAEFAQLD 61 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCK 140 + +E + I+ +++ + + + +H N+ GT + + Sbjct: 62 VTDE----AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYH----VNVYGTICLLR 113 Query: 141 AVYSSWMKEHGGSIVNIIVPTKAGFPL-------------------AVHSGAARAGVY 179 ++ ++ NI+ + A G + + Sbjct: 114 SMVRH-------NVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >2PK3-A nrPDB Length = 321 Score = 57.2 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 47/271 (17%), Positives = 80/271 (29%), Gaps = 59/271 (21%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 A++TG A +GK + L E V SR E K V I Sbjct: 14 RALITGVAGFVGKYLANHLTEQNVEVFGTSRNNE---------------AKLPNVEMISL 58 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGW---HAVLETNLTGTF 136 +I + + V ++ K +++ + + W TN+ GT Sbjct: 59 DIMDSQRVKKVISDI-----KPDYIFHLAAKSSVK-------DSWLNKKGTFSTNVFGTL 106 Query: 137 YMCKAVYSSWMKEHGGSIVNIIVPTKAGFPL--------------AVHSGAARAGVYNLT 182 ++ AV S + I+ I + G L G ++A V L Sbjct: 107 HVLDAVRDSNLD---CRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLA 163 Query: 183 KSLALEWACSGI---RINCVAPG---VIYSQTAVENYGSWGQSFFEGSFQKIPA---KRI 233 + + I N + PG +Q + E + + Sbjct: 164 RQYVKAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDF 223 Query: 234 GVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 ++ +LLS TG +V G Sbjct: 224 TDVRDIVQAY-WLLSQYGK--TGDVYNVCSG 251 >3ORF-A nrPDB Length = 251 Score = 53.0 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 30/213 (14%), Positives = 65/213 (30%), Gaps = 21/213 (9%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 + G + +V GG+ +G +VK N + + Sbjct: 14 LVPRGSHMSKNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNAD------------ 61 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS-PAEHISSKGWHAVL 128 EEE+ ++++ K++ V GG + K ++ Sbjct: 62 -----HSFTIKDSGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMI 116 Query: 129 ETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALE 188 + NL F + + + + G ++ + GA +A +++ K LA E Sbjct: 117 DMNLYSAFASA-HIGAKLLNQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASE 175 Query: 189 WA--CSGIRINCVAPGVIYSQTAVENYGSWGQS 219 +G + P + + T + Sbjct: 176 NGGLPAGSTSLGILPVTLDTPTNRKYMSDANFD 208 >2GN9-A nrPDB Length = 344 Score = 52.2 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 60/165 (36%), Gaps = 26/165 (15%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLE--LGSNVVIASRKLERLKSAADELQANLPPTK 70 +L Q ++TGG GK V+++L+ +++ SR + A E Sbjct: 16 QNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEF-------N 68 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 R+ ++R+ E +N ++ ++ ++ + + P + ++T Sbjct: 69 DPRMRFFIGDVRDLERLNYALE-------GVDICIHAAALKHV-PIAEYNP---LECIKT 117 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAAR 175 N+ G + A + + + I + T GA + Sbjct: 118 NIMGASNVINACLKNAISQ------VIALSTDKAANPINLYGATK 156 >1I3M-A nrPDB Length = 348 Score = 50.7 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 60/182 (32%), Gaps = 28/182 (15%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASR--KLERLKSAADELQANLPPTKQARVIPI 77 +VTGGA IG V ELLE G V+ R + E + V Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 + +I ++ + L K +++ G + + + + NLTGT Sbjct: 64 EMDILDQGALQRLFKKY-----SFMAVIHFAGLKAMGESVQKPLDYYR----VNLTGTIQ 114 Query: 138 MCKAVYSSWMKEHGGSIVNIIVPTKAGFPLA-------------VHSGAARAGVYNLTKS 184 + + + + +K +V T G P G ++ + + + Sbjct: 115 LLEIMKAHGVKN----LVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRD 170 Query: 185 LA 186 L Sbjct: 171 LC 172 >1UDA-A nrPDB Length = 338 Score = 50.7 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 56/130 (43%), Gaps = 13/130 (10%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +VTGG+ IG +LL+ G +V+I L+ L ++ + + ++ Sbjct: 2 RVLVTGGSGYIGSHTCVQLLQNGHDVII----LDNLCNSKRSVLPVIERLGGKHPTFVEG 57 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 +IRNE L+ L I+ +++ G + + + + + N+ GT + Sbjct: 58 DIRNE----ALMTEILHDH-AIDTVIHFAGLKAVGESVQKPLEYYDN----NVNGTLRLI 108 Query: 140 KAVYSSWMKE 149 A+ ++ +K Sbjct: 109 SAMRAANVKN 118 >1Z45-A nrPDB Length = 699 Score = 49.5 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 56/139 (40%), Gaps = 20/139 (14%) Query: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 M + + S ++ +VTGGA IG V EL+E G + V+A + Sbjct: 1 MTAQLQSES-------TSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSV- 52 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 A L + + + ++ + + + + K KI+ +++ G + + + I Sbjct: 53 ---ARLEVLTKHHIPFYEVDLCDRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIP 104 Query: 121 SKGWHAVLETNLTGTFYMC 139 + +H N+ GT + Sbjct: 105 LRYYHN----NILGTVVLL 119 >6ACF-A nrPDB Length = 367 Score = 49.1 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 + L+G+V V G + + + L E G+ +++ E + A +E A Sbjct: 163 KEAFGSDSLEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAK-- 219 Query: 68 PTKQARVIPIQCNI 81 + ++C+I Sbjct: 220 AVDPNDIYGVECDI 233 >6BWL-A nrPDB Length = 328 Score = 48.4 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 48/270 (17%), Positives = 88/270 (32%), Gaps = 45/270 (16%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +VTGGA IG+ +VK LL+ V I + E +L + IQ Sbjct: 2 KILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQC-----IQG 56 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 +I++++ V L ++ ++F L + S A E + GTF + Sbjct: 57 DIKDKKLVAQLFEN--NSFDLCYHLAASINV-------QDSIDDARATFENDTIGTFNLL 107 Query: 140 KAVYSS----------WMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKS--LAL 187 + + + + +I I A ++ N+ S A Sbjct: 108 EQCLNYDVKMVFMSTCMVYDKATNIQGIS--ELDPIKPASPYAGSKIAAENMVLSYYYAY 165 Query: 188 EWACSGIR-INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV---------PE 237 + IR N P + +T E G F +P G E Sbjct: 166 KLPVVVIRPFNTYGP---FQKTGGE--GGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVE 220 Query: 238 EVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 + + V + ++ G ++ G+ + Sbjct: 221 DCADFVV--AAGYSAKANGHIINAGTGQDI 248 >3ENK-A nrPDB Length = 341 Score = 47.2 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +VTGGA IG ELL G +VVIA + + A A + + Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAI----ARIEKITGKTPAFHET 62 Query: 80 NIRNEEEVNNLVKS 93 ++ +E + + + Sbjct: 63 DVSDERALARIFDA 76 >4G5H-A nrPDB Length = 363 Score = 46.5 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 22/162 (13%), Positives = 60/162 (37%), Gaps = 25/162 (15%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSN-VVIASRKLERLKSAADELQANLPPTKQARV 74 ++ ++TGG G A++K L+ + I SR ++ + +++ Sbjct: 23 FDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKK-------YNNSKL 75 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 ++R+ + V ++ +++ + + + E + ++TN+ G Sbjct: 76 KFYIGDVRDSQSVETAMRDV-------DYVFHAAALKQVPSCEFFPVE----AVKTNIIG 124 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARA 176 T + ++ +K+ I + T G ++A Sbjct: 125 TENVLQSAIHQNVKK------VICLSTDKAAYPINAMGISKA 160 >2Q1W-A nrPDB Length = 333 Score = 46.1 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 38/126 (30%), Gaps = 21/126 (16%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + +TG IG I + LLE G VV + + ++ Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRRE---------HLKDHPNLTFVE 72 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 +I + VN L+ + + +V+ W+ TN G + Sbjct: 73 GSIADHALVNQLIGDL-----QPDAVVHTAASYKD-------PDDWYNDTLTNCVGGSNV 120 Query: 139 CKAVYS 144 +A Sbjct: 121 VQAAKK 126 >1OOE-A nrPDB Length = 236 Score = 46.1 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 73/211 (34%), Gaps = 28/211 (13%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G+V IV GG +G AI++ + G V+ + I Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLS---------------ANDQADSNIL 46 Query: 77 IQCNIRNEEEVNNLVKSTLDTF--GKINFLVNNGGGQFLSPAEHISSKGW----HAVLET 130 + N E+ ++++ T + +++ + GG A SSK + +++ Sbjct: 47 VDGNKNWTEQEQSILEQTASSLQGSQVDGVFCVAGGWAGGSA---SSKDFVKNADLMIKQ 103 Query: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLAL--E 188 ++ + K + K G + P + G A+A V++LT SLA Sbjct: 104 SVWSSAIAAKLATTHL-KPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDS 162 Query: 189 WACSGIRINCVAPGVIYSQTAVENYGSWGQS 219 + + P + + + + S Sbjct: 163 GLPDNSAVLTIMPVTLDTPMNRKWMPNADHS 193 >3RFT-A nrPDB Length = 267 Score = 45.3 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 27/178 (15%), Positives = 57/178 (32%), Gaps = 46/178 (25%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + +VTG A +G+ + + L + + +A +E +Q Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSPLDPAGPNEEC--------------VQ 49 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 C++ + VN +V + +V+ GG P + +L+ N+ G + + Sbjct: 50 CDLADANAVNAMVA-------GCDGIVHLGGISVEKP--------FEQILQGNIIGLYNL 94 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVH-------------SGAARAGVYNLTK 183 +A + IV G+ G ++ NL + Sbjct: 95 YEAARAH----GQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLAR 148 >1GY8-A nrPDB Length = 397 Score = 44.5 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 55/160 (34%), Gaps = 25/160 (15%) Query: 20 VAIVTGGATGIGKAIVKELLEL-GSNVVIAS---------RKLERLKSAADELQ---ANL 66 +V GGA IG V+ LL +VVI +E ++ A +LQ Sbjct: 4 RVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPK 63 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA 126 PP ++RNE+ +N + G I+ +V+ + + K + Sbjct: 64 PPWADRYAALEVGDVRNEDFLNGVF----TRHGPIDAVVHMCAFLAVGESVRDPLKYYDN 119 Query: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFP 166 N+ G + +A + I+ G P Sbjct: 120 ----NVVGILRLLQA----MLLHKCDKIIFSSSAAIFGNP 151 >5N2I-A nrPDB Length = 232 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 25/64 (39%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 + G V GG G+ + + G V++ SR ER ++ A EL LP Sbjct: 17 VSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAG 76 Query: 76 PIQC 79 + Sbjct: 77 AAEA 80 >1DIR-A nrPDB Length = 241 Score = 43.4 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 32/210 (15%), Positives = 64/210 (30%), Gaps = 29/210 (13%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 + + +V GG +G V+ V + + + + Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASID---------------VVENEEASASVI 50 Query: 77 IQCNIRNEEEVNNLVKSTLDTFG--KINFLVNNGGGQFLSPAEHIS-----SKGWHAVLE 129 ++ E+ + + G K++ ++ GG A+ S W + Sbjct: 51 VKMTDSFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIW 110 Query: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLA--L 187 T+ + K +KE G + G P + G A+ V+ L +SLA Sbjct: 111 TSTISSHLATKH-----LKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKN 165 Query: 188 EWACSGIRINCVAPGVIYSQTAVENYGSWG 217 SG V P + + ++ Sbjct: 166 SGMPSGAAAIAVLPVTLDTPMNRKSMPEAD 195 >2PZM-A nrPDB Length = 330 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 25/170 (14%), Positives = 53/170 (31%), Gaps = 29/170 (17%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 ++TGGA +G +++ L G +++ + LPP VI + Sbjct: 22 RILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREV-------LPPVAGLSVI--EG 72 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 ++ + + S T +V++ W TN+ G+ + Sbjct: 73 SVTDAGLLERAFDSFKPTH-----VVHSAAAYKD-------PDDWAEDAATNVQGSINVA 120 Query: 140 KAVYSSWMKEH--------GGSIVNIIVPTKAGFPLAVHSGAARAGVYNL 181 KA + +K G + +P + G ++ Sbjct: 121 KAASKAGVKRLLNFQTALCYGRPATVPIPIDSPTAPFTSYGISKTAGEAF 170 >1LU9-A nrPDB Length = 287 Score = 42.2 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 6/85 (7%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 G ++G+ A+V G +G L G+ VV+ RKL++ ++AAD + + Sbjct: 115 GSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRF------K 168 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTF 98 V ++ VK F Sbjct: 169 VNVTAAETADDASRAEAVKGAHFVF 193 >4R1T-A nrPDB Length = 337 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 28/220 (12%), Positives = 64/220 (29%), Gaps = 25/220 (11%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 + GQV VTG I +VK LLE G V R + K+ + R+ Sbjct: 7 SVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNG----HLRELEGAKERL 62 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHI------SSKGWHAVL 128 + ++ + + + + + + + P + + + +A Sbjct: 63 TLCKADLLDYQSLREAIN-------GCDGVFHTASPVTDDPEQMVEPAVIGTKNVINAAA 115 Query: 129 ETNLTGTFYMCKAVYSSW-MKEHGGSIVNIIVPTKAGF--PLAVHSGAARAGVYNLTKSL 185 E N+ + ++V+ + F + + + Sbjct: 116 EANVRRVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGK----MVAEQA 171 Query: 186 ALEWAC-SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGS 224 A E A G+ + + P ++ + + Sbjct: 172 AWEEAKEKGVDLVVINPVLVQGPLLQTTVNASVLHILKYL 211 >2NNL-D nrPDB Length = 337 Score = 41.8 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 40/268 (14%), Positives = 85/268 (31%), Gaps = 49/268 (18%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 Q + VTG + IG +V LLE G V R +K L P + + Sbjct: 4 QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLD---LPKAETHLTL 60 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG-WHAVLETNLTGT 135 + ++ +E + +K G ++ SK + V++ + G Sbjct: 61 WKADLADEGSFDEAIKGCT-------------GVFHVATPMDFESKDPENEVIKPTIEGM 107 Query: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGF-----PLAVHSG--------AAR--AGVYN 180 + K+ ++ +V P+ S A + A +Y Sbjct: 108 LGIMKSCAAAKTVR---RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYF 164 Query: 181 LTKSLALEWA-----CSGIRINCVAPGVIYSQTAVENYGSWGQSFF------EGSFQKIP 229 ++K+LA + A + I + P ++ + + + E + I Sbjct: 165 VSKTLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIR 224 Query: 230 AKRIGVPEEVSSVVCFLLSP---AASFI 254 + +++ + +L +I Sbjct: 225 QGQFVHLDDLCNAHIYLFENPKAEGRYI 252 >4J2O-A nrPDB Length = 363 Score = 41.8 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 40/242 (16%), Positives = 91/242 (37%), Gaps = 42/242 (17%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ-AR 73 + + +V ++TGG G A++K LE K R+ S ++ Q ++ A+ Sbjct: 20 MFKDKVLLITGGTGSFGNAVLKRFLE-------TDIKEIRIFSRDEKKQDDMRKKYHSAK 72 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWH--AVLETN 131 + ++R+ + N + ++++ + + + S +H ++TN Sbjct: 73 LKFYIGDVRDYNSILNATR-------GVDYIYHAAA------LKQVPSCEFHPMEAVKTN 119 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 + GT + +A + +K +V + KA +P G ++A + + + + Sbjct: 120 VLGTENVLEAAIQNHVK----RVVCLSTD-KAVYP-INAMGISKAMMEKVMVAKSRNLEG 173 Query: 192 SGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPA--------KRIGVPEEVSSVV 243 ++ V G Y GS F + Q P + + E+ +V Sbjct: 174 ----LDTVICGTRYGNVMASR-GSVIPLFVDQIRQGKPLTITDPNMTRFMMTLEDAVDLV 228 Query: 244 CF 245 + Sbjct: 229 LY 230 >3VPX-A nrPDB Length = 364 Score = 41.4 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 3/74 (4%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 + L G+ V G + A+ + L E G+ ++I E ++ A D A Sbjct: 163 KEAFGDDSLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAV 221 Query: 68 PTKQARVIPIQCNI 81 + + + +I Sbjct: 222 GINE--IYSQEADI 233 >5B6K-A nrPDB Length = 366 Score = 40.7 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 36/103 (34%), Gaps = 10/103 (9%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 V+G I + +V++LL+ V+ + R E+ D L+ + ++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKG----DHLKNVIFKGGDFNYEIVK- 77 Query: 80 NIRNEEEVNNLVKSTLDTFGK-INFLVNNGGGQFLSPAEHISS 121 +I + + GK I +++ + + Sbjct: 78 DISDP----TAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKD 116 >1OC2-A nrPDB Length = 348 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 32/199 (16%), Positives = 58/199 (29%), Gaps = 34/199 (17%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + IVTGGA IG V + +V + K +ANL RV + Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLD----KLTYAGNKANLEAILGDRVELVV 60 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 +I + E V+ L + +V+ S + TN GT+ + Sbjct: 61 GDIADAELVDKLAAKA-------DAIVHYAAESH----NDNSLNDPSPFIHTNFIGTYTL 109 Query: 139 CKAVYSSWMK-------------------EHGGSIVNIIVPTKAGFPLAVHSGAARAGVY 179 +A ++ G + + + + +A Sbjct: 110 LEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASD 169 Query: 180 NLTKSLALEWACSGIRINC 198 + K+ + NC Sbjct: 170 LIVKAWVRSFGVKATISNC 188 >3PVZ-A nrPDB Length = 399 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 26/182 (14%), Positives = 60/182 (32%), Gaps = 15/182 (8%) Query: 20 VAIVTGGATGIGKAIVKE-LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +V GGA IG+A+ KE + + + +++++ Sbjct: 37 RFLVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYI-NGDFQTFA 95 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 +I + E + + G+ ++++N + + +++ N+ T Sbjct: 96 LDIGSIE-----YDAFIKADGQYDYVLNLSALKHVR--SEKDPFTLMRMIDVNVFNTDKT 148 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 + + K++ V T GA++ + + E A S R Sbjct: 149 IQQSIDAGAKKYF------CVSTDKAANPVNMMGASKRIMEMFLMRKSEEIAISTARFAN 202 Query: 199 VA 200 VA Sbjct: 203 VA 204 >3SXP-A nrPDB Length = 362 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 32/197 (16%), Positives = 61/197 (30%), Gaps = 23/197 (11%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELG--SNVVIAS--RKLERLKSAADELQANLPPTKQ 71 L+ Q ++TGGA +G + E + VV+ R + + Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETN 131 + I +I N ++ L K ++L + + V++TN Sbjct: 68 FKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQ------ELVMKTN 115 Query: 132 LTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLA------VHSGAARAGVYNLTKSL 185 + + S K S + TKA + G ++ + S Sbjct: 116 YQAFLNLLEIARSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMDEFVLSH 175 Query: 186 ALEWACSGIR-INCVAP 201 + + G+R N P Sbjct: 176 SNDNVQVGLRYFNVYGP 192 >1VL0-A nrPDB Length = 292 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 49/178 (27%), Gaps = 52/178 (29%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 ++TG +G+ I K+L V+ + Sbjct: 14 KILITGANGQLGREIQKQLKGKNVEVIPTDVQ--------------------------DL 47 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 +I N VN K N ++N + E + + + N G + Sbjct: 48 DITNVLAVNKFFNE-----KKPNVVINCAAHTAVDKCE----EQYDLAYKINAIGPKNLA 98 Query: 140 KAVYSSWMKEHGGSIVNIIV----PTKAGFPL--------AVHSGAARAGVYNLTKSL 185 A YS G IV I +A P+ G + N K+L Sbjct: 99 AAAYSV-----GAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >1GPJ-A nrPDB Length = 404 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 30/69 (43%), Gaps = 2/69 (2%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSN-VVIASRKLERLKSAADELQANLPPTKQA 72 G L + +V G +GK + K L++ G V++A+R ER A +L + Sbjct: 163 GSLHDKTVLVVGAGE-MGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFDEL 221 Query: 73 RVIPIQCNI 81 + ++ Sbjct: 222 VDHLARSDV 230 >1ZZE-A nrPDB Length = 342 Score = 38.7 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 49/128 (38%), Gaps = 17/128 (13%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 +G + +VTG + +V++LLE G V +R +L + A P + V+ Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVE 69 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 ++ + + ++K G ++ S+K + V+ + GT Sbjct: 70 ---DMLKQGAYDEVIKGA-------------AGVAHIASVVSFSNK-YDEVVTPAIGGTL 112 Query: 137 YMCKAVYS 144 +A + Sbjct: 113 NALRAAAA 120 >4K28-A nrPDB Length = 269 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 5 AKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQ 63 A + P G+ A+V G G+G AI L E G +++ + R+ + + L Sbjct: 115 AAHKHGFEP---AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLG 170 Query: 64 ANLPP 68 P Sbjct: 171 NGFPG 175 >4PVC-A nrPDB Length = 342 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 44/127 (34%), Gaps = 16/127 (12%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 V+G I + IV LL+ V+ ++R E+ ++ + N P V+P + Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNN--PKFSMEVVP---D 57 Query: 81 IRNEEEVNNLVKSTLDTFGK-INFLVNNGGGQFLSPAEHISSKGWHAVL-ETN-LTGTFY 137 I + GK I +++ I+ ++ N + G + Sbjct: 58 ISKLD----AFDHVFQKHGKDIKIVLHTASPFCF----DITDSERDLLIPAVNGVKGILH 109 Query: 138 MCKAVYS 144 K + Sbjct: 110 SIKKYAA 116 >6GCS-E nrPDB Length = 375 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 50/135 (37%), Gaps = 26/135 (19%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ--ARV 74 G A V G +G + +L + G+ VV+ R +E+ V Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYR---------EEMAKRHLKVTGDLGVV 102 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 ++ ++RN E ++ V+ + + +VN G +K ++ + ++ G Sbjct: 103 NFLEMDLRNLESIDEAVRHS-------DIVVNLIG-------REYETKNFN-YYDVHVEG 147 Query: 135 TFYMCKAVYSSWMKE 149 + +AV + Sbjct: 148 ARRIAEAVKKHNIAR 162 >5INT-A nrPDB Length = 220 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 19/139 (13%), Positives = 46/139 (33%), Gaps = 43/139 (30%) Query: 13 PGLLQGQVAIVTGG---------------ATG-IGKAIVKELLELGSNVVIASRKLERLK 56 LQG+ ++T G ++G +G AI + + LG+ V++ S Sbjct: 1 SNALQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS------- 53 Query: 57 SAADELQANLPPTKQARVIPIQCNIR--NEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS 114 + ++ E +++++ + + ++ ++ Sbjct: 54 --------------GPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVADYR 99 Query: 115 PAE----HISSKGWHAVLE 129 P + K AV+E Sbjct: 100 PKYVHDNKMKKKNGDAVIE 118 >5K1S-A nrPDB Length = 362 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 35/84 (41%), Gaps = 4/84 (4%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G+ ++TG + G+G + V+ G+ V+ + ++++ + A +R + Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKE---AGADEVIVSRGLD 239 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGK 100 ++R + V ++ G Sbjct: 240 FASDVRKRTQ-GAGVDVAVEIVGS 262 >3OND-A nrPDB Length = 488 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 34/73 (46%), Gaps = 11/73 (15%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 ++ G+VA+V G +GK L + G+ V++ D + A + +V Sbjct: 262 MIAGKVAVVAGYGD-VGKGCAAALKQAGARVIVT---------EIDPICALQATMEGLQV 311 Query: 75 IPIQCNIRNEEEV 87 + ++ ++ +E ++ Sbjct: 312 LTLE-DVVSEADI 323 >6DEB-A nrPDB Length = 285 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 42/112 (37%), Gaps = 19/112 (16%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ A++ G + +G+ + LL G+ V + K + L + QA+L V Sbjct: 158 LEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDL--SLYTRQADLIIVAAGCVN 215 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 ++ ++ E +V + G L + + + V Sbjct: 216 LLRSDMVKE-----------------GVIVVDVGINRLESGKIVGDVDFEEV 250 >2Z95-A nrPDB Length = 345 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 7/81 (8%) Query: 16 LQGQVAIVTGGATGI-GKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 + G+ A++TG G G + K LLE G V A R R A L ++ Sbjct: 1 MSGKRALITGI-RGQDGAYLAKLLLEKGYEVYGADR---RSGEFASWRLKELGIENDVKI 56 Query: 75 IPIQCNIRNEEEVNNLVKSTL 95 I ++ + ++ Sbjct: 57 I--HMDLLEFSNIIRTIEKVQ 75 >1RKX-A nrPDB Length = 357 Score = 38.0 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 41/237 (17%), Positives = 74/237 (31%), Gaps = 47/237 (19%) Query: 17 QGQVAIVTG--GATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 QG+ VTG G G G + L +G+ V + A + + + A Sbjct: 8 QGKRVFVTGHTGFKG-GW-LSLWLQTMGATV-------KGYSLTAPTVPSLFETARVAD- 57 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 +Q I + + N L++S + + + + P +S TN+ G Sbjct: 58 -GMQSEIGDIRDQNKLLESIREF--QPEIVFHMAA----QPLVRLSYSEPVETYSTNVMG 110 Query: 135 TFYMCKAVYSSWMKEHGG--SIVNIIVP-------------TKAGFPLAVHSGAARAGVY 179 T Y+ +A ++ GG ++VNI ++ Sbjct: 111 TVYLLEA-----IRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAE 165 Query: 180 NLTKSLAL------EWACSGIRINCVAPGVIY--SQTAVENYGSWGQSFFEGSFQKI 228 +T S + G + V G + A++ FE S I Sbjct: 166 LVTSSYRNSFFNPANYGQHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVI 222 >3LK7-A nrPDB Length = 451 Score = 37.6 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 20/51 (39%), Gaps = 1/51 (1%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANL 66 + + +V G A G+A + L +LG+ V + K A L Sbjct: 7 FENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEG 56 >1BXK-A nrPDB Length = 355 Score = 37.6 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 72/191 (37%), Gaps = 32/191 (16%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + ++TGGA IG A+V+ ++ S+ V+ KL A L + P + R + Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTY----AGNLMSLAPVAQSERFAFEK 57 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 +I + E+ + + + +++ + S G A +ETN+ GT+ + Sbjct: 58 VDICDRAELARVFTEH-----QPDCVMHLAAESHVDR----SIDGPAAFIETNIVGTYTL 108 Query: 139 CKAVYSSW--MKEHGGSIVN---IIVPTKAG--------------FPLAVHSGAARAGVY 179 +A + W + E S I G + + A++A Sbjct: 109 LEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSD 168 Query: 180 NLTKSLALEWA 190 +L ++ + Sbjct: 169 HLVRAWLRTYG 179 >4KTT-E nrPDB Length = 327 Score = 37.2 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 43/127 (33%), Gaps = 28/127 (22%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 + +VTG +G+A+ KE + + V + R K Sbjct: 21 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK-------------------FE 61 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137 Q N+ + +N V + F + + +V+ + E+ A + N+ + Sbjct: 62 QVNLLD----SNAVHHIIHDF-QPHVIVHCAAERRPDVVENQP----DAASQLNVDASGN 112 Query: 138 MCKAVYS 144 + K + Sbjct: 113 LAKEAAA 119 >4EUF-A nrPDB Length = 418 Score = 37.2 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 32/96 (33%), Gaps = 9/96 (9%) Query: 19 QVAIVTGGATGIGKA--IVKELLELGSNVV-------IASRKLERLKSAADELQANLPPT 69 + ++ G ++G G A I ++ + R++ + Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLV 105 K + + E + ++K D FGKI+ V Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >2C20-A nrPDB Length = 330 Score = 36.8 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 61/161 (37%), Gaps = 12/161 (7%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 ++ GGA IG VK+L++ G +VV+ + A E + + + Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLR--D 61 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCK 140 + +E + ++ + LV G P ++ ++ + A+ + F + K Sbjct: 62 VFTQENIEAVMHFAA------DSLV---GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDK 112 Query: 141 AVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNL 181 ++SS +G V++I P G + + + Sbjct: 113 FIFSSTAATYGEVDVDLITEETMTNP-TNTYGETKLAIEKM 152 >1R66-A nrPDB Length = 337 Score = 36.8 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 43/273 (15%), Positives = 86/273 (31%), Gaps = 55/273 (20%) Query: 22 IVTGGATGIGKAIVKELLELGS--------NVVIASRKLERLKSAADELQANLPPTKQAR 73 +VTGGA IG V++LL G+ +V+ S ++ + A+ R Sbjct: 4 LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNRANLAPVDAD------PR 56 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 + + +IR+ ++ +V+ + S G ETN+ Sbjct: 57 LRFVHGDIRD-------AGLLARELRGVDAIVHFAAESHVDR----SIAGASVFTETNVQ 105 Query: 134 GTFYMCKAVYSSWMKE--------HGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSL 185 GT + + + + GSI + + A++AG + ++ Sbjct: 106 GTQTLLQCAVDAGVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAY 165 Query: 186 ALEWACS-GIR--INCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPA--------KRIG 234 + I N P Q + + + +G +P + + Sbjct: 166 HRTYGLDVRITRCCNNYGPY----QHPEKLIPLFVTNLLDG--GTLPLYGDGANVREWVH 219 Query: 235 VPEEVSSVVCFLLSPAASFITGQSVDVDGGRSL 267 + + L A G+ + GG L Sbjct: 220 TDDHCRGIALVLAGGRA----GEIYHIGGGLEL 248 >1KEU-A nrPDB Length = 361 Score = 36.1 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 31/206 (15%), Positives = 72/206 (34%), Gaps = 40/206 (19%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 ++TGGA IG A+V+ +++ + V+ KL A L++ ++ R Sbjct: 2 KILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTY----AGNLESLSDISESNRYNFEHA 57 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 +I + E+ + + + + +++ + + + +ETN+ GT+ + Sbjct: 58 DICDSAEITRIFEQY-----QPDAVMHLAAESHVDRSI-TGPAAF---IETNIVGTYALL 108 Query: 140 KAVYSSWMK-----------------EHGG----------SIVNIIVPTKAGFPLAVHSG 172 + W E G S+ + + + Sbjct: 109 EVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYS 168 Query: 173 AARAGVYNLTKSLALEWACSGIRINC 198 A++A +L ++ + I NC Sbjct: 169 ASKASSDHLVRAWRRTYGLPTIVTNC 194 >3NJ4-A nrPDB Length = 435 Score = 36.1 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE 61 ++ G+VA+V G +GK + L G+ V+I AA E Sbjct: 213 MIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAME 258 >3ZU2-A nrPDB Length = 422 Score = 35.7 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 41/131 (31%), Gaps = 17/131 (12%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNV----VIASRKLERLKSAA-----DELQANLPPT 69 + +V G +TG G A + G V R E K Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL- 128 K I + ++E + + G+++ ++ + + + + + +++ L Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLASPRRTHPK--TGEVFNSALK 181 Query: 129 ----ETNLTGT 135 NL G Sbjct: 182 PIGNAVNLRGL 192 >1DB3-A nrPDB Length = 372 Score = 35.7 bits (81), Expect = 0.028, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 41/123 (33%), Gaps = 9/123 (7%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA++TG G + + LLE G V R+ + + P T + Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ + + +++ V N G S + + + GT + Sbjct: 62 GDLSDTSNLTRILREVQPDE------VYNLGAMSHVAVSFESPEY---TADVDAMGTLRL 112 Query: 139 CKA 141 +A Sbjct: 113 LEA 115 >4J6F-A nrPDB Length = 382 Score = 35.3 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 30/78 (38%), Gaps = 1/78 (1%) Query: 3 SWAKGRSYLAPGLLQ-GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE 61 ++ G L L G+ +VTG + G+G AI++ G+ + + + Sbjct: 191 AYLTGERMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDIG 250 Query: 62 LQANLPPTKQARVIPIQC 79 QA + + ++ Sbjct: 251 AQAVVTRGQGDLAEAVEA 268 >3X2F-A nrPDB Length = 411 Score = 34.9 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 58/157 (36%), Gaps = 27/157 (17%) Query: 15 LLQGQVAIVTGGATG-IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 L+ G+ +V G G G+ I LG+ V++ + A + +P + + Sbjct: 194 LVAGKNVVVAG--YGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAVK 251 Query: 74 VIPIQC------NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQF----LSPAEHISSKG 123 + ++ ++E++ +L ++ N G + E I+ + Sbjct: 252 IADFVITASGNTDVLSKEDILSLKDGA---------VLANAGHFNVEIPVRVLEEIAVEK 302 Query: 124 WHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVP 160 + A N+TG + + + E G +VN+ Sbjct: 303 FEA--RPNVTG-YTLENGKTVFLLAE--GRLVNLAAG 334 >3HFS-A nrPDB Length = 338 Score = 34.9 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 21/154 (13%), Positives = 50/154 (32%), Gaps = 19/154 (12%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + A V GG + +VK LL+ G V R + K ++ L + + + Sbjct: 10 KTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQK----KVSHLLELQELGDLKIFR 65 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 ++ +E + +F+ + +P S + +++ + G + Sbjct: 66 ADLTDELSFEAPIA-------GCDFVFHVA-----TPVHFASEDPENDMIKPAIQGVVNV 113 Query: 139 CKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSG 172 KA + + ++ +G Sbjct: 114 MKACTRAKSVK---RVILTSSAAAVTINQLDGTG 144 >3DMF-A nrPDB Length = 381 Score = 34.5 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 53/160 (33%), Gaps = 23/160 (14%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 L P ++G+ + G G A+ L +G+ VV D+L + L K Sbjct: 227 LGPEGVRGRQVLDLGAGYG---ALTLPLARMGAEVV----------GVEDDLASVLSLQK 273 Query: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130 ++ + +++ V L + + +V N ++ + V Sbjct: 274 GLEANALKA-----QALHSDVDEALTEEARFDIIVTNPPFHVGGAVILDVAQAFVNVAAA 328 Query: 131 NLT--GTFYMCK---AVYSSWMKEHGGSIVNIIVPTKAGF 165 L G F++ Y ++E G+ + V Sbjct: 329 RLRPGGVFFLVSNPFLKYEPLLEEKFGAFQTLKVAEYKVL 368 >6ACQ-A nrPDB Length = 302 Score = 34.5 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 35/101 (34%), Gaps = 14/101 (13%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 + G +V ++ GA +G I + G VV+ K E + D + NL Sbjct: 14 LVPRGSHMKKVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKL 71 Query: 70 KQARV------------IPIQCNIRNEEEVNNLVKSTLDTF 98 + I ++ + + ++++ ++ Sbjct: 72 VKKGKIEEATKVEILTRISGTVDLNMAADCDLVIEAAVERM 112 >4B4O-A nrPDB Length = 298 Score = 34.5 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 22/65 (33%), Positives = 29/65 (44%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +V GG IG A+ + L G V + SRK + DEL A+ P+ A V Sbjct: 2 RVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGE 61 Query: 80 NIRNE 84 NI N Sbjct: 62 NILNP 66 >3SC6-A nrPDB Length = 287 Score = 34.5 bits (78), Expect = 0.060, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 50/178 (28%), Gaps = 52/178 (29%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 I+TG +GK + +EL ++ +KL Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKL--------------------------L 40 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 +I N +V +V+ + + +++ + AE K N G + Sbjct: 41 DITNISQVQQVVQEI-----RPHIIIHCAAYTKVDQAE----KERDLAYVINAIGARNV- 90 Query: 140 KAVYSSWMKEHGGSIVNII------------VPTKAGFPLAVHSGAARAGVYNLTKSL 185 AV S + G +V I GA++ K L Sbjct: 91 -AVASQLV---GAKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >3RUE-A nrPDB Length = 351 Score = 34.5 bits (78), Expect = 0.060, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 57/141 (40%), Gaps = 15/141 (10%) Query: 4 WAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQ 63 ++ + + ++TG A IG ++++LL+L V+ + DE++ Sbjct: 11 MSRYEEITQQLIFSPKTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVK 70 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNG--GGQFLSPAEHISS 121 + + +R I+ +IR+ ++K ++ +++ G S + I++ Sbjct: 71 TLVSTEQWSRFCFIEGDIRDLTTCEQVMK-------GVDHVLHQAALGSVPRSIVDPITT 123 Query: 122 KGWHAVLETNLTGTFYMCKAV 142 TN+TG + A Sbjct: 124 N------ATNITGFLNILHAA 138 >2DFV-A nrPDB Length = 347 Score = 34.1 bits (77), Expect = 0.073, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 35/82 (42%), Gaps = 6/82 (7%) Query: 14 GLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP-PTK 70 G + G+ ++TG +G A+ K G+ VI S + + A ++ A+ Sbjct: 163 GPISGKSVLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSDFRRELAKKVGADYVINPF 219 Query: 71 QARVIPIQCNIRNEEEVNNLVK 92 + V+ +I + V+ ++ Sbjct: 220 EEDVVKEVMDITDGNGVDVFLE 241 >4KUG-A nrPDB Length = 290 Score = 33.7 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 31/90 (34%), Gaps = 13/90 (14%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + V G T +G IV+ G V++ K E + + +L I Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 79 ------------CNIRNEEEVNNLVKSTLD 96 +++ + + +V++ ++ Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIE 90 >6C55-A nrPDB Length = 340 Score = 33.7 bits (76), Expect = 0.094, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 27/66 (40%), Gaps = 5/66 (7%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 LQG+ V G + G A + L + G +VVI R A ++ P + + Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVK-- 71 Query: 76 PIQCNI 81 Q ++ Sbjct: 72 --QADV 75 >1RPN-A nrPDB Length = 335 Score = 33.7 bits (76), Expect = 0.095, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 29/79 (36%), Gaps = 8/79 (10%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVV-IASRKLERLKSAADELQANLPPTKQA 72 G + + A+VTG G + K LLE G V + +R+ + EL + Sbjct: 11 GSMT-RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYE- 68 Query: 73 RVIPIQCNIRNEEEVNNLV 91 ++ + V V Sbjct: 69 -----DGDMADACSVQRAV 82 >2EXX-A nrPDB Length = 306 Score = 33.7 bits (76), Expect = 0.099, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 10/85 (11%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQAR 73 ++ ++ +V GG G ++ + LLE G V + +R K AA EL+ Sbjct: 8 MVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPR--KKAAKELRLQ-------G 58 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTF 98 +Q + ++ + + TF Sbjct: 59 AEVVQGDQDDQVIMELALNGAYATF 83 >6GBN-A nrPDB Length = 438 Score = 33.7 bits (76), Expect = 0.100, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIA 48 ++ G+VA+V G +GK L G+ V++ Sbjct: 216 MMAGKVAVVAGYGD-VGKGSAASLRGAGARVIVT 248 >3H9U-A nrPDB Length = 436 Score = 33.7 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 38/98 (38%), Gaps = 10/98 (10%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRK-LERLKSAADELQANLPPTKQAR 73 ++ G+ A V G +GK L G+ VV+ + L++A + Q L Sbjct: 208 MIAGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEE 266 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKI--NFLVNNGG 109 N++ + + + F ++ + +V N G Sbjct: 267 AHIFVTTTGNDDIITS------EHFPRMRDDAIVCNIG 298 >4EJ6-A nrPDB Length = 370 Score = 33.4 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 35/99 (35%), Gaps = 12/99 (12%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQA 72 G+ G + GG IG V+ G+ VI S + + A+E+ A A Sbjct: 178 SGIKAGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGAT------A 230 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQ 111 V P ++ V + G ++ ++ G Sbjct: 231 TVDPSAGDV-----VEAIAGPVGLVPGGVDVVIECAGVA 264 >3N58-A nrPDB Length = 464 Score = 33.4 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIA 48 ++ G+VA+V G +GK + L G+ V + Sbjct: 244 MMAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVT 276 >1ZDL-A nrPDB Length = 517 Score = 33.4 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 1/29 (3%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASR 50 +V GG +G G A KE +LG V +A Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADY 63 >7REQ-A nrPDB Length = 727 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 13/95 (13%), Positives = 33/95 (34%), Gaps = 6/95 (6%) Query: 34 IVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKS 93 I +LG +V + ++A ++A++ + + + ++ Sbjct: 616 IATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHL------TLVPALRK 669 Query: 94 TLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 LD G+ + L+ GG + + G + Sbjct: 670 ELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIY 704 >4J90-A nrPDB Length = 222 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 31/84 (36%), Gaps = 1/84 (1%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 G ++ + V G G +I KEL +G V+ E++ + A + Sbjct: 2 GRIKNKQFAVIGLGR-FGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEE 60 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDT 97 + IRN E V + + + Sbjct: 61 NELLSLGIRNFEYVIVAIGANIQA 84 >5JXW-A nrPDB Length = 498 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 32/73 (43%), Gaps = 11/73 (15%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 +L G+ +V G +GK + L +G+ V++ D + A + +V Sbjct: 268 MLAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVT---------EIDPICALQASMEGYQV 317 Query: 75 IPIQCNIRNEEEV 87 ++ ++ +E ++ Sbjct: 318 SVLE-DVVSEADI 329 >4KDR-A nrPDB Length = 223 Score = 33.0 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 15/106 (14%), Positives = 30/106 (28%), Gaps = 21/106 (19%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA-------------AD 60 G L G+ + G GI + + + G+ V E L+ A Sbjct: 59 GGLFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ 115 Query: 61 ELQANLPPTKQARVIPIQC-----NIRNEEEVNNLVKSTLDTFGKI 101 E + + C ++ + + V + G + Sbjct: 116 ETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDV 161 >4EJ0-A nrPDB Length = 342 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 27/162 (16%), Positives = 45/162 (27%), Gaps = 28/162 (17%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 IVTG A IG +VK L E G +IA L R + + C I Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKN---------------LVDCEI 60 Query: 82 RNEEEVNNLVKS-TLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCK 140 + + V+ FGK+ +++ N + + Sbjct: 61 DDYLDKTEFVERFARGDFGKV------RAVFHEGACSDTMETDGRYMMDNNFRYSRAVLD 114 Query: 141 AVYSSWMKEHGGSIVNIIVPTKA------GFPLAVHSGAARA 176 A + + S I + G ++ Sbjct: 115 ACLAQGAQFLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >1JAY-A nrPDB Length = 212 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRK 51 +VA++ GG +GK + L LG +V+ SR+ Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRR 33 >5UOG-A nrPDB Length = 344 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 34/97 (35%), Gaps = 5/97 (5%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRK-LERLKSAADELQANLPPT 69 L+P L+G+ + G IG AI + L G ++ +R E L + Sbjct: 157 LSPLSLRGRTVGLFGLGR-IGLAIARRLEAFGVSIAYHTRTPREGLGFTYHPTLVGMAEA 215 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVN 106 ++ + + VN L G L+N Sbjct: 216 VDTLIVIVPGTASTLKAVNA---DVLSALGPKGVLIN 249 >4KDC-A nrPDB Length = 246 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 15/106 (14%), Positives = 30/106 (28%), Gaps = 21/106 (19%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA-------------AD 60 G L G+ + G GI + + + G+ V E L+ A Sbjct: 59 GGLFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ 115 Query: 61 ELQANLPPTKQARVIPIQC-----NIRNEEEVNNLVKSTLDTFGKI 101 E + + C ++ + + V + G + Sbjct: 116 ETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDV 161 >3DC2-A nrPDB Length = 529 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 32/92 (34%), Gaps = 1/92 (1%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 G+ V G IG+ + + + G+ VV + ++A ++ AR I Sbjct: 142 GKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFI 200 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG 109 ++ E L+ K ++ N Sbjct: 201 SVHLPKTPETAGLIDKEALAKTKPGVIIVNAA 232 >1O89-A nrPDB Length = 345 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLK 56 +VTG + G+G V L +LG VV S + + Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHE 206 >5TC4-A nrPDB Length = 316 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 32/92 (34%), Gaps = 10/92 (10%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 G+ +V G + +G I L G++ A + P +Q + I Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH-------ERPGGDATVTISHRYTPKEQLKKHTI 211 Query: 78 QCN-IRNEEEVNNLV--KSTLDTFGKINFLVN 106 + + + + NL+ + I+ +N Sbjct: 212 LADIVISAAGIPNLITADMIKEGAAVIDVGIN 243 >3HZZ-A nrPDB Length = 467 Score = 32.6 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 44/113 (38%), Gaps = 9/113 (7%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSN----VVIASRKLERLKSAADELQANLPPTKQA 72 QG ++ G + G+G + + G VV + +K E +S E A + + Sbjct: 246 QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAE--AIIDRNAEG 302 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGK--INFLVNNGGGQFLSPAEHISSKG 123 + ++ +E K + G I+ + + G + + +++ KG Sbjct: 303 YKFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGRETFGASVYVTRKG 355 >5UZH-A nrPDB Length = 345 Score = 32.6 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 30/77 (38%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA++TG G + + LLE G V R+ + E +A+ + Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLLY 61 Query: 79 CNIRNEEEVNNLVKSTL 95 ++ + + +++ Sbjct: 62 GDLTDTGNLISIIAKIK 78 >5F5N-A nrPDB Length = 289 Score = 32.6 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 24/81 (29%), Gaps = 9/81 (11%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 + +VTG G A V+ LL G V R A V + Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGT---------DAARALAAAGVSLV 51 Query: 78 QCNIRNEEEVNNLVKSTLDTF 98 ++ ++ + + F Sbjct: 52 TGDLNDQASLRAAMADVHGVF 72 >3BIC-A nrPDB Length = 762 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 40/112 (35%), Gaps = 15/112 (13%) Query: 25 GGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNE 84 G G K I +LG +V I + A + A++ + + + Sbjct: 616 GHDRG-AKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTL--- 671 Query: 85 EEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 V L+K ++ G+ + LV GG I + + + E ++ F Sbjct: 672 --VPELIKEL-NSLGRPDILVMCGGV--------IPPQDYEFLFEVGVSNVF 712 >2WEK-A nrPDB Length = 341 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 31/81 (38%), Gaps = 1/81 (1%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 GL +G+ +VT A G G+ +L + VI + + + L + P + Sbjct: 139 GLSEGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTE 197 Query: 74 VIPIQCNIRNEEEVNNLVKST 94 + E V+ + +S Sbjct: 198 PVGTVLKQEYPEGVDVVYESV 218 >3EDC-A nrPDB Length = 360 Score = 32.2 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 35/92 (38%), Gaps = 9/92 (9%) Query: 16 LQGQVAIVTGGATG---------IGKAIVKELLELGSNVVIASRKLERLKSAADELQANL 66 L G+ +++ G AT I AI +LG++VV++ + +++ + L Sbjct: 56 LAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLL 115 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTF 98 +I + ++ V + F Sbjct: 116 AQRVSGLIINYPLDDQDAIAVEAACTNVPALF 147 >6G2J-P nrPDB Length = 377 Score = 32.2 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 46/118 (38%), Gaps = 19/118 (16%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 + G VA V G +G+ +V L +GS V+I R ++ ++ Sbjct: 50 SVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYR------CDVYDIMHLRLMGDLGQL 103 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 ++ + R+++ + V+ + N ++N G ++ + + V N+ Sbjct: 104 TFLEWDARDKDSIRKAVQHS-------NVVINLIGREW-----ETRNFDFEDVF-VNI 148 >2GAS-A nrPDB Length = 307 Score = 32.2 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 34/90 (37%), Gaps = 8/90 (8%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 ++ G IG+ IV ++ G N A + + + + + + VI ++ Sbjct: 4 KILILGPTGAIGRHIVWASIKAG-NPTYALVRKTITAANPETKEELIDNYQSLGVILLEG 62 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGG 109 +I + E + +K + ++ G Sbjct: 63 DINDHETLVKAIKQV-------DIVICAAG 85 >3GFB-A nrPDB Length = 350 Score = 32.2 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 33/82 (40%), Gaps = 6/82 (7%) Query: 14 GLLQGQVAIVTGGA--TGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP-PTK 70 G + G+ ++TG +G A+ K G+ VI S E + A ++ A+ Sbjct: 164 GPIAGRSTLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSEFRRKLAKKVGADYVVNPF 220 Query: 71 QARVIPIQCNIRNEEEVNNLVK 92 + + +I + V ++ Sbjct: 221 EEDPVKFVMDITDGAGVEVFLE 242 >1WVG-A nrPDB Length = 359 Score = 32.2 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 44/123 (35%), Gaps = 15/123 (12%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 QG+ VTG G + L E+G+ V + + S + ++ N Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHI---- 63 Query: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 +IR+ E++ + + K + + P +S + TN+ GT Sbjct: 64 --GDIRDFEKLRSSIAEF-----KPEIVFHMAA----QPLVRLSYEQPIKTYSTNVMGTV 112 Query: 137 YMC 139 ++ Sbjct: 113 HLL 115 >1BW9-B nrPDB Length = 356 Score = 31.8 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 9 SYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 ++ G L G +V G +G ++ E G+ +++A ER+ A + Sbjct: 167 AHRGLGSLDGLTVLVQGLGA-VGGSLASLAAEAGAQLLVADTDTERV---AHAVALGHTA 222 Query: 69 TKQARVIPIQCNI 81 V+ C++ Sbjct: 223 VALEDVLSTPCDV 235 >3DFZ-A nrPDB Length = 223 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 42/115 (36%), Gaps = 11/115 (9%) Query: 6 KGRSYLAPGL-LQGQVAIVTGGATGIGKAIVKELLELGS--NVVIASRKLERLKSAAD-- 60 +GR L L+G+ +V GG T I +K L+ G+ VV + E + A Sbjct: 18 EGRHMYTVMLDLKGRSVLVVGGGT-IATRRIKGFLQEGAAITVVAPTVSAEINEWEAKGQ 76 Query: 61 -ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS 114 ++ + + N++ VN VK + + LVN Sbjct: 77 LRVKRKKVGEEDLLNVFFIVVATNDQAVNKFVKQHIKN----DQLVNMASSFSDG 127 >3CT4-A nrPDB Length = 332 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 34/99 (34%), Gaps = 9/99 (9%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELG---SNVVIASRKLERLKSAADELQANLPPTKQAR 73 G+VA+V+GG +G A + G + V A + +++ Sbjct: 45 SGKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLL 103 Query: 74 VIP-IQCNIRNEEEVNNLVKSTLDTFGKI----NFLVNN 107 +I ++ N E + + +I + V N Sbjct: 104 IIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVEN 142 >2HK7-A nrPDB Length = 269 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 29/63 (46%), Gaps = 1/63 (1%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + +V G G +A++ L++ G+ V + +R E+ A + + + + + +Q Sbjct: 124 KSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKVQ 182 Query: 79 CNI 81 + Sbjct: 183 VIV 185 >3H0K-A nrPDB Length = 178 Score = 31.8 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 41/100 (41%), Gaps = 20/100 (20%) Query: 19 QVAIVTGGATGIGK-AIVKELLELGSNVV-----------IASRKLERLKSAADELQANL 66 +V ++TG G GK K L E G+ V+ I ++ ERL A L+ Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFAKRLREIY 59 Query: 67 PPTKQARVIPIQC-----NIRNEEEVNNLVKSTLDTFGKI 101 AR+ + ++ + V +L + ++ F ++ Sbjct: 60 GDGVVARLCVEELGTSNHDLVVFDGVRSLAE--VEEFKRL 97 >6BII-A nrPDB Length = 333 Score = 31.4 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 G+ + G IG+AI K G ++ +R R A EL A P ++ Sbjct: 150 GKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARS--RKPEAEKELGAEFKPLEE 200 >5GUP-L nrPDB Length = 377 Score = 31.4 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 41/114 (35%), Gaps = 18/114 (15%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 + G VA V G +G+ +V L +GS V++ R + P ++ Sbjct: 50 SVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPY------DTMHLRPMGDLGQI 103 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 I ++ N ++++ + +V+ +N + + + V Sbjct: 104 IFMEWNGKDKDSIRKVVEH------------SNVVINLVGREWETKNFDFEDVF 145 >4WPG-A nrPDB Length = 289 Score = 31.0 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 36/125 (28%), Gaps = 34/125 (27%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 ++TG +G + L E G + V + + Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVD--------------------------VAEMD 40 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCK 140 I NE++V + T LV + A K + N+TG+ + K Sbjct: 41 ITNEDKVEAVFAQVKPT------LVYHCAAYTAVDAAEDEGKALNE--AINVTGSENIAK 92 Query: 141 AVYSS 145 A Sbjct: 93 ACGKY 97 >4A10-A nrPDB Length = 447 Score = 31.0 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 48/113 (42%), Gaps = 9/113 (7%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 QG + ++ G + G+G + + ++ G + +A + ++A L +L + + Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAE--LG 276 Query: 77 IQCNIRNE-----EEVNNLVKSTLDTFGK-INFLVNNGGGQFLSPAEHISSKG 123 I +I ++ E L K ++ G+ + + + G + ++ +G Sbjct: 277 ITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGRVTFGLSVIVARRG 329 >4BKP-A nrPDB Length = 336 Score = 31.0 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 19/121 (15%), Positives = 37/121 (30%), Gaps = 31/121 (25%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +VTGG+ +GKAI ++++ G+ LP V Sbjct: 24 RILVTGGSGLVGKAI-QKVVADGA---------------------GLPGEDWVFVSSKDA 61 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVN-NGGGQFLSPAEHISSKGWHAVLETN---LTGT 135 ++ + + L + T +++ L + W + N L Sbjct: 62 DLTDTAQTRALFEKVQPTH-----VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSA 116 Query: 136 F 136 F Sbjct: 117 F 117 >1F14-A nrPDB Length = 310 Score = 31.0 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 29/77 (37%), Gaps = 7/77 (9%) Query: 23 VTGGATGI-GKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 VT G+ G I + G VV+ + + L + ++ +L + + Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFA------ 71 Query: 82 RNEEEVNNLVKSTLDTF 98 N + + V+ TL T Sbjct: 72 ENPKAGDECVEKTLSTI 88 >4LSW-A nrPDB Length = 318 Score = 31.0 bits (69), Expect = 0.71, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 32/90 (35%), Gaps = 4/90 (4%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 G+ A V G IG + + L G ++ I+ + A D T V + Sbjct: 145 GRRAGVLGLGR-IGFEVARRLA--GFDMQISYSDIAPKSYAPDWTFVEDAVTLARDVDFL 201 Query: 78 QCNIRNEEEVNNLV-KSTLDTFGKINFLVN 106 + ++V + ++ G L+N Sbjct: 202 FVTLAASAATRHIVGRDVIEALGPEGMLIN 231 >2ZJ8-A nrPDB Length = 720 Score = 31.0 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 37/102 (36%), Gaps = 13/102 (12%) Query: 11 LAPGLLQGQVAIV---TGGATGIGKAIV---KELLELGSNVVIASRKLERLKSAADELQA 64 L G+L+G+ A++ T + I + L + G V I LK+ A+E Sbjct: 32 LKSGILEGKNALISIPTASGKTLIAEIAMVHRILTQGGKAVYIVP-----LKALAEEKFQ 86 Query: 65 NL--PPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFL 104 RV + +++E + T K + L Sbjct: 87 EFQDWEKIGLRVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128 >4OFX-A nrPDB Length = 319 Score = 30.7 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 31/115 (26%), Gaps = 10/115 (8%) Query: 24 TGGATGIGKAIVKELLELGSNVVIA--SRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 T G TGIG I G V+I + + + L A + T Sbjct: 73 TSGNTGIG--IALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAAY------ 124 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136 + E +L K L + + + + NL+ Sbjct: 125 DDPESHISLAKRLNQEIPNSYILDQYSNAENPDIHYQTTGQEILDDMGENLSMVV 179 >3S8M-A nrPDB Length = 422 Score = 30.7 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 13/97 (13%), Positives = 31/97 (31%), Gaps = 11/97 (11%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNV----VIASRKLERLKSAADELQANLPPTKQARV 74 + +V G ++G G A + G V + K+ + K A+ Sbjct: 62 KKVLVIGASSGYGLA-SRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKA 120 Query: 75 IP-----IQCNIRNEEEVNNLVKSTLDTFGK-INFLV 105 I + ++ +++ G ++ +V Sbjct: 121 AGLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVV 157 >2OWO-A nrPDB Length = 671 Score = 30.7 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 16 LQGQVAIVTGGATGIGKAIVK-ELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 G+ ++TG + + + K L+ELG+ V + K L A + + L ++ + Sbjct: 598 FAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGI 657 Query: 75 IPIQ 78 I Sbjct: 658 EVID 661 >4G2N-A nrPDB Length = 345 Score = 30.7 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 18/46 (39%), Gaps = 3/46 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE 61 L G+ + G IG+AI G + I RL A +E Sbjct: 171 LTGRRLGIFGMGR-IGRAIATR--ARGFGLAIHYHNRTRLSHALEE 213 >3D64-A nrPDB Length = 494 Score = 30.7 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE 61 ++ G++A+V G +GK + L LG+ V + AA E Sbjct: 274 MIAGKIAVVAGYGD-VGKGCAQSLRGLGATVWVTEIDPICALQAAME 319 >2C54-A nrPDB Length = 379 Score = 30.7 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 21/139 (15%), Positives = 46/139 (33%), Gaps = 24/139 (17%) Query: 4 WAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQ 63 + Y L+ +TG I I + L G V+ + K + + +++ Sbjct: 18 ELEREQYWPSENLK---ISITGAGGFIASHIARRLKHEGHYVIASDWK--KNEHMTEDMF 72 Query: 64 ANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG 123 + RV+ + E V+++ + G + F+ +N Sbjct: 73 CDEFHLVDLRVMENCLKVT--EGVDHVF-NLAADMGGMGFIQSNHSV------------- 116 Query: 124 WHAVLETNLTGTFYMCKAV 142 ++ N +F M +A Sbjct: 117 ---IMYNNTMISFNMIEAA 132 >3HDH-A nrPDB Length = 302 Score = 30.7 bits (68), Expect = 0.80, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 21/53 (39%), Gaps = 1/53 (1%) Query: 23 VTGGATGI-GKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74 VT G+ G I + G VV+ + + L + ++ +L + + Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF 70 >5ENV-A nrPDB Length = 347 Score = 30.7 bits (68), Expect = 0.83, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 39/114 (34%), Gaps = 16/114 (14%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLEL-GSNVVIASRKLERLKSAADELQANL 66 ++ + L+ G ++G A G+G ++ + + G V+ E + L Sbjct: 160 KALKSANLMAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGID---------GGEGKEEL 209 Query: 67 PPTKQARVIPIQCNIRNEEEVNNLVKSTLD--TFGKINFLVNNGGGQFLSPAEH 118 + V + E+++ V D G IN V+ + + Sbjct: 210 FRSIGGEVFI---DFTKEKDIVGAVLKATDGGAHGVINVSVSEAAIEASTRYVR 260 >2GGS-A nrPDB Length = 273 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 12/120 (10%), Positives = 35/120 (29%), Gaps = 29/120 (24%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 ++TG + +G + + L E V+ E + ++ Sbjct: 4 LITGASGQLGIELSRLLSER-HEVIKVYNSSEIQG-------------------GYKLDL 43 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 + + + + + + ++N + E K + N ++ +A Sbjct: 44 TDFPRLEDFIIK-----KRPDVIINAAAMTDVDKCEIEKEKAYK----INAEAVRHIVRA 94 >4HTF-A nrPDB Length = 285 Score = 30.7 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 23/73 (31%), Gaps = 6/73 (8%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 + P L + GG G ++ E G V++ + + A +A Sbjct: 65 MGPQKL---RVLDAGGGEGQ---TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDN 118 Query: 71 QARVIPIQCNIRN 83 + ++ + Sbjct: 119 MQFIHCAAQDVAS 131 >4LEC-A nrPDB Length = 212 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 29/127 (22%), Positives = 51/127 (40%), Gaps = 18/127 (14%) Query: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70 + L+G+ A+ G TG+ IV L LG++V I RK+ L+ +QANLPP Sbjct: 53 MGAVELRGRSAVELGAGTGL-VGIVAAL--LGAHVTITDRKVA-LEFLKSNVQANLPPHI 108 Query: 71 QARVI--------------PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPA 116 Q + + P + ++ ++ L ++ D + L +N L+ Sbjct: 109 QTKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLACR 168 Query: 117 EHISSKG 123 Sbjct: 169 IRYERDN 175 >3ORR-A nrPDB Length = 377 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%), Gaps = 2/54 (3%) Query: 30 IGKAIVKELLELGSNVVIASRKLE-RLKSAADE-LQANLPPTKQARVIPIQCNI 81 +GK + + ++G VV+ + + A E +QA K + +C++ Sbjct: 23 LGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLGQKCDV 76 >3DQQ-A nrPDB Length = 421 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 31/183 (16%), Positives = 55/183 (30%), Gaps = 41/183 (22%) Query: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 +VTGG+ G+ + ++ + G + A P + +A V+ C Sbjct: 219 LVTGGS-GLAMGLARQWAKHG---------------VSQARSAGYPLSGRAVVLSGSC-- 260 Query: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKA 141 + N V + V + + + L + + + Sbjct: 261 --SQMTNQQVAFYRQHAPTRDVDVARC-------LSSETREAYAEALAQ-----WVLSQD 306 Query: 142 VYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGA--ARAGVYNLTKSLALEWACSGIRINCV 199 + M ++ T+A + GA A V L LA A GI V Sbjct: 307 SELAPM-------ISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIV 359 Query: 200 APG 202 A G Sbjct: 360 AGG 362 >4PZE-A nrPDB Length = 284 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 25/230 (10%), Positives = 64/230 (27%), Gaps = 28/230 (12%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + + G T +G I + +G NVV+ ++ + ++L + + Sbjct: 4 RTVGIVGAGT-MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 + ++ D + ++ + + + K ++ N+ Sbjct: 63 DKASALARIKG--STSYDDLKATDIVIEAATENYDLKVKIL--KQIDGIVGENVIIASNT 118 Query: 139 CKAVYSSWMK--EHGGSIVNI-------IVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189 + + + ++ S A V L+K + Sbjct: 119 SSISITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSK----QL 174 Query: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 I + +PG + ++ EG + PEE+ Sbjct: 175 GKYPITVKN-SPGFVVNRILCPMINEAFCVLGEG---------LASPEEI 214 >3G1U-A nrPDB Length = 437 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 37/98 (37%), Gaps = 10/98 (10%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRK-LERLKSAADELQANLPPTKQAR 73 ++ G+ V G +GK L G+ VV+ + L+++ + Q L A Sbjct: 209 MIAGKTCCVCGYGD-VGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVALVEDVMAD 267 Query: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKI--NFLVNNGG 109 N++ + + D F + + +V N G Sbjct: 268 AHIFVTTTGNDDIITS------DHFPHMRDDAIVCNIG 299 >5YWN-A nrPDB Length = 334 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 24/156 (15%), Positives = 45/156 (28%), Gaps = 16/156 (10%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80 V+G + + I+ +L G VV + R E+ + + Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYE----------- 53 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETN-LTGTFYMC 139 + E L ++ ++ + K + N Sbjct: 54 VVKVLEQKGAFDEALKKHPEVTIFLHTASPVTFE--VEDTEKEI-LIPAINGTKYVLQSI 110 Query: 140 KAVYSSWMKEHG-GSIVNIIVPTKAGFPLAVHSGAA 174 K V + S+V + VP + G P V S A+ Sbjct: 111 KDVAPQITRVVYTSSVVAMSVPEELGSPDVVLSEAS 146 >4WOK-A nrPDB Length = 336 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 16/45 (35%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 + +V GGA IG K L G V+ +SA Sbjct: 9 MSANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVR 53 >4DGK-A nrPDB Length = 501 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 12/76 (15%), Positives = 20/76 (26%), Gaps = 7/76 (9%) Query: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIR 82 V G G G A+ L G V++ ++ + A VI Sbjct: 6 VIGAGFG-GLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVI------T 58 Query: 83 NEEEVNNLVKSTLDTF 98 + + L Sbjct: 59 DPSAIEELFALAGKQL 74 >3PEF-A nrPDB Length = 287 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 28/77 (36%), Gaps = 2/77 (2%) Query: 29 GI-GKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEV 87 GI G A+ K L++ G +V I +R E+ + A L A T V + Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELA-ALGAERAATPCEVVESCPVTFAMLADP 68 Query: 88 NNLVKSTLDTFGKINFL 104 + G + + Sbjct: 69 AAAEEVCFGKHGVLEGI 85 >4B4V-A nrPDB Length = 303 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G+ A+V G + +GK + LL+ + V I + + L QA++ + Sbjct: 178 AGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVK--QADIIVGAVGKAEL 235 Query: 77 IQCN 80 IQ + Sbjct: 236 IQKD 239 >1C0L-A nrPDB Length = 363 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKL 52 + +V G IG + L G +V I +R L Sbjct: 7 KRVVVLGSGV-IGLSSALILARKGYSVHILARDL 39 >5M65-A nrPDB Length = 479 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE 61 +L G+VA+V G +GK L + G V+++ AA E Sbjct: 257 MLSGKVAMVAGFGD-VGKGSAASLRQAGCRVMVSEVDPICALQAAME 302 >3L07-A nrPDB Length = 285 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 +G A+V G + +GK + + LL + V R LKS +A++ + Sbjct: 160 EGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKS--HTTKADILIVAVGKPNF 217 Query: 77 IQCNIRNEEEV 87 I ++ E V Sbjct: 218 ITADMVKEGAV 228 >3R9I-A nrPDB Length = 260 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 10/75 (13%) Query: 19 QVAIVTGGATGIGK-----AIVKELLELGSNVVIAS-----RKLERLKSAADELQANLPP 68 ++ +VT G G+GK AI L + G V+ R L+ + + + Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFAIGLRNLDLIMGCERRVVYDFVN 62 Query: 69 TKQARVIPIQCNIRN 83 Q Q I++ Sbjct: 63 VIQGDATLNQALIKD 77 >2EER-A nrPDB Length = 347 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 21/45 (46%), Gaps = 3/45 (6%) Query: 19 QVAIVTGGATGIGKAIVKELLEL--GSNVVIASRKLERLKSAADE 61 + +V G G+G + ++ + G+ ++ + E L++A Sbjct: 172 KTLVVIGAGGGLG-TMAIQIAKAVSGATIIGVDVREEALEAAKRA 215 >2VN8-A nrPDB Length = 375 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 51/158 (32%), Gaps = 26/158 (16%) Query: 17 QGQVAIVTGGATGIG-KAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G+ ++ G + G+G AI + S+ A EL L Sbjct: 183 TGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQD-------ASELVRKLGAD------ 229 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 ++ + + V+ L + +F+++N GG + A K W L Sbjct: 230 ----DVIDYKS--GSVEEQLKSLKPFDFILDNVGGSTETWAPDF-LKKWSGATYVTLVTP 282 Query: 136 F--YMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS 171 F M + + M + G V + F VH Sbjct: 283 FLLNMDRLGIADGMLQTG---VTVGSKALKHFWKGVHY 317 >4E0B-A nrPDB Length = 313 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 4/45 (8%) Query: 19 QVAIVTGGATGIGKAIVKELLE---LGSNVVIASRKLERLKSAAD 60 +VA++ G A GIG+A+ L GS++ + AAD Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAAD 48 >5EGS-A nrPDB Length = 376 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 5/79 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ + G TGI + + G+ V A + + A E+ + V+ Sbjct: 82 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYA-VEASAIWQQAREVVRFNGLEDRVHVL 137 Query: 76 PIQCN-IRNEEEVNNLVKS 93 P + E+V+ +V Sbjct: 138 PGPVETVELPEQVDAIVSE 156 >3FBG-A nrPDB Length = 346 Score = 29.9 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 17 QGQVAIVTGGATGIGKAIVKELLEL-GSNVVIASRKLERLK 56 +G+ ++ GA G+G +I ++ + G V+ + + E ++ Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIE 189 >3TLM-A nrPDB Length = 992 Score = 29.9 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 29/170 (17%), Positives = 51/170 (30%), Gaps = 27/170 (15%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKS----AADELQANLPPTKQARV 74 +V ++TG G AI + + G N +A R + A++ +A ARV Sbjct: 619 RVIMITGDNKGTAIAICRRIGIFGENEDVADRAYTGREFDDLPLAEQREACRRACCFARV 678 Query: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNG--------------GGQFLSPAEHI- 119 P E G + VN+ G A + Sbjct: 679 EPTHK--SKIVEYLQSFDEITAMTG--DG-VNDAPALKKAEIGIAMGSGTAVAKTASEMV 733 Query: 120 -SSKGWHAVLETNLTG--TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFP 166 + + ++ G + K + + G +V I + G P Sbjct: 734 LADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLP 783 >1U3W-A nrPDB Length = 374 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 14/115 (12%) Query: 2 ASWAKGRSYLAPGLLQG-----QVAIVTGGAT-------GIGKAIVKELLELGSNVVIAS 49 AS + + G G +VA VT G+T G+G ++V G+ +IA Sbjct: 163 ASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAV 222 Query: 50 RKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFL 104 + + A EL A Q PIQ + +E + V + + G+++ + Sbjct: 223 DINKDKFAKAKELGATECINPQDYKKPIQEVL--KEMTDGGVDFSFEVIGQLDTM 275 >1YXY-A nrPDB Length = 234 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 22/55 (40%), Gaps = 5/55 (9%) Query: 145 SWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCV 199 M++ G I+ + G PL +G G+ L A E GIR N V Sbjct: 9 KLMEQLKGGII-VSCQALPGEPLYSETG----GIMPLMAKAAQEAGAVGIRANSV 58 >6H5E-B nrPDB Length = 437 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 29/80 (36%) Query: 40 ELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFG 99 G+N+ ++S A + + + ++ + N + +D FG Sbjct: 81 NEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFG 140 Query: 100 KINFLVNNGGGQFLSPAEHI 119 +I+ +VNN + + Sbjct: 141 EIDIMVNNIAETISNKGIKL 160 >2BIS-A nrPDB Length = 440 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 43/113 (38%), Gaps = 18/113 (15%) Query: 33 AIVKELLELGSNVVIASRKLER--------LKSAADELQAN--LPPTKQARVIPIQCNIR 82 AI + L LG V++ + R ++ +E+Q R+ I + Sbjct: 27 AISEALASLGHEVLVFTPSHGRFQGEEIGKIRVFGEEVQVKVSYEERGNLRIYRIGGGLL 86 Query: 83 NEEEV-----NNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS-SKGWHAVLE 129 + E+V + L++ + TFG+ + L+ N P + WH V Sbjct: 87 DSEDVYGPGWDGLIRKAV-TFGRASVLLLN-DLLREEPLPDVVHFHDWHTVFA 137 >5LV5-A nrPDB Length = 403 Score = 29.5 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 30/79 (37%), Gaps = 5/79 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 L+G+ + G TGI + + G+ V A + + A E+ + V+ Sbjct: 109 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYA-VEASAIWQQAREVVRLNGLEDRVHVL 164 Query: 76 PIQCN-IRNEEEVNNLVKS 93 P + E V+ +V Sbjct: 165 PGPVETVELPERVDAIVSE 183 >1YB5-A nrPDB Length = 351 Score = 29.5 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 46/122 (37%), Gaps = 22/122 (18%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA----------------AD 60 G+ +V G + G+G A + G ++ + E K D Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYID 229 Query: 61 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 +++ + +I + N+ +++ S L G++ +V + G ++P + ++ Sbjct: 230 KIKKYVGEKGIDIIIEMLANVNLSKDL-----SLLSHGGRV-IVVGSRGTIEINPRDTMA 283 Query: 121 SK 122 + Sbjct: 284 KE 285 >3IP1-A nrPDB Length = 404 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 G ++ GG IG A V L G++ VI S E ++ A EL A+ Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGAD 260 >3TQH-A nrPDB Length = 321 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Query: 17 QGQVAIVTGGATGIGKAIVKELLEL-GSNVVIAS--RKLERLKSAADELQANLPPTKQAR 73 QG V ++ GA G+G + +L + G+ V+ + R LK+ E N Sbjct: 152 QGDVVLIHAGAGGVG-HLAIQLAKQKGTTVITTASKRNHAFLKALGAEQCINYHEEDFLL 210 Query: 74 VIPIQCN 80 I + Sbjct: 211 AISTPVD 217 >6DKH-A nrPDB Length = 346 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 50/139 (35%), Gaps = 20/139 (14%) Query: 12 APGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANL----- 66 G LQG+ ++G IG IV + LG+ ++ + R S E+ A++ Sbjct: 167 QAGELQGKRVFISGVGP-IGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQ 225 Query: 67 -PPTKQARVIPIQCNIR-----NEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS 120 + ++ + VN ++ T +V G G ++ ++ Sbjct: 226 NDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRAR----GVMVQVGMGGAMAEFPMMT 281 Query: 121 SKGWHAVLETNLTGTFYMC 139 G E +L G+F Sbjct: 282 LIG----KEISLRGSFRFT 296 >5GXF-A nrPDB Length = 330 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 15/36 (41%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLERLK 56 +VTG A G+G L LG V + + E Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >5MH6-A nrPDB Length = 308 Score = 29.5 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 35/100 (35%), Gaps = 2/100 (2%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPT 69 Y P L G+ V G T +G+ +V LG VV R + + + + + Sbjct: 127 YEEPFTLAGERVCVVGLGT-LGRGVVDRAAALGMEVVGVRRSGDPVDNVSTVYTPDRLHE 185 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINF-LVNNG 108 A + +E +V + + + LVN Sbjct: 186 AIADARFVVLATPLTDETEGMVAAPEFETMREDASLVNVA 225 >4B3J-A nrPDB Length = 736 Score = 29.1 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 38/110 (34%), Gaps = 21/110 (19%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA--------ADELQANLPPTK 70 + V G +G I + G VV+ LE A L+ + Sbjct: 342 KRIGVLGAGM-MGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQE 400 Query: 71 QARVIPIQ----CNIRNEEEVNNLVKSTLD-------TFGKI-NFLVNNG 108 ++ + + + + + V+ ++++ + FG+I + + N Sbjct: 401 RSDALLARITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNA 450 >2WWR-A nrPDB Length = 330 Score = 29.1 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD---ELQANLPPTKQA 72 L + G IG+AI + L G + + + R + AA+ E + Q+ Sbjct: 153 LTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQS 211 Query: 73 RVIPIQCNIR 82 I + C++ Sbjct: 212 DFIVVACSLT 221 >3QWB-A nrPDB Length = 334 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 31/80 (38%) Query: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 +G ++ A G+G + + L G++ + + E+LK A + L + ++ Sbjct: 148 KGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVASTDEKLKIAKEYGAEYLINASKEDILR 207 Query: 77 IQCNIRNEEEVNNLVKSTLD 96 N + V+ S Sbjct: 208 QVLKFTNGKGVDASFDSVGK 227 >1VIM-A nrPDB Length = 200 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 20/61 (32%), Gaps = 2/61 (3%) Query: 19 QVAIVTGGATG--IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 + V G I KA L+ LG V + + + D L + V+ Sbjct: 48 RSIFVIGAGRSGYIAKAFAMRLMHLGYTVYVVGETVTPRITDQDVLVGISGSGETTSVVN 107 Query: 77 I 77 I Sbjct: 108 I 108 >4GBJ-A nrPDB Length = 297 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 33/92 (35%), Gaps = 7/92 (7%) Query: 13 PGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVI---ASRKLERLKSAADELQANLPPT 69 + ++A + G +G I + LLE G +V+ + K E L + N Sbjct: 1 SNAMSEKIAFL--GLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDA 58 Query: 70 KQARVIPIQCNIRNEEEVNNLVK-STLDTFGK 100 I + ++ V L ++ GK Sbjct: 59 ITPGGIVFSV-LADDAAVEELFSMELVEKLGK 89 >3HG7-A nrPDB Length = 324 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL 62 +S+ G L+G+ ++ G IG+ I G V+ SR R ++ D++ Sbjct: 131 QSHPYQG-LKGRTLLILG-TGSIGQHIAHTGKHFGMKVLGVSRSG-RERAGFDQV 182 >6GPK-A nrPDB Length = 373 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 28/77 (36%), Gaps = 1/77 (1%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA-ADELQANLPPTKQARVIPIQ 78 VA++TG G + + LLE G V R+ + + L N + + Sbjct: 26 VALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHY 85 Query: 79 CNIRNEEEVNNLVKSTL 95 ++ + + ++ Sbjct: 86 GDLTDSTCLVKIINEVK 102 >4UUP-A nrPDB Length = 341 Score = 28.7 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 32/105 (30%), Gaps = 13/105 (12%) Query: 21 AIVTGGATGIGKAIVKELLELGS----NVVIASRKLERLKSAADELQANLPPTKQARVIP 76 ++TG A IG A+ + + VV+ ++ A + + L + Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 77 IQCNIRNEEEVNNLVKST--------LDTFGKINFLVNNGGGQFL 113 + + EE V + + L N G + Sbjct: 67 VVAT-DDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKV 110 >3ABT-A nrPDB Length = 662 Score = 28.7 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 39/119 (32%), Gaps = 15/119 (12%) Query: 17 QGQVAIV-TGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G+V I+ +G + G A ++L G +V + + A + N A V+ Sbjct: 107 TGKVIIIGSGVS---GLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVV 163 Query: 76 PI-----QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 + +VN + L G + + + ++ +LE Sbjct: 164 TGLGGNPMAVVSK--QVNMELAKIKQKCP----LYEANGQAVPKEKDEMVEQEFNRLLE 216 >5Y2D-A nrPDB Length = 465 Score = 28.7 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 25/163 (15%), Positives = 50/163 (30%), Gaps = 23/163 (14%) Query: 20 VAIV--TGGATGIGKAIVKELLELGSNVVIASRKLER--LKSAADELQANLPPTKQARVI 75 AI+ TGG GIG AI +++ +I + K+ER L +L +L + + Sbjct: 227 TAIISKTGGNHGIGFAIPSNMVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQNSYDNKEG 286 Query: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET-NLTG 134 + ++ + G ++ K E NL G Sbjct: 287 AVVISVEKDSPAKK------------------AGILVWDLITEVNGKKVKNTNELRNLIG 328 Query: 135 TFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAG 177 + + V +++ + + + A Sbjct: 329 SMLPNQRVTLKVIRDKKERAFTLTLAERKNPNKKETISAQNGA 371 >4TSK-A nrPDB Length = 350 Score = 28.7 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 4/65 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLER-LKSAAD--ELQANLPPTKQA 72 L + V G + G A + L + G +VVI R K+ AD + A +++ Sbjct: 15 LADKRIAVIGYGS-QGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADGFRVMAVGEAVEES 73 Query: 73 RVIPI 77 VI I Sbjct: 74 DVIMI 78 >3WR5-A nrPDB Length = 406 Score = 28.7 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 26 GATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP----IQCNI 81 A IG A+++ L +V + RL A ++ + + + P + N+ Sbjct: 204 AAGRIGLAVLRRLAP--FDVKLHYTDRHRLPEAVEKELGLVWHDTREDMYPHCDVVTLNV 261 Query: 82 RNEEEVNNLV-KSTLDTFGKINFLVNNG 108 E +++ TL F + ++VN Sbjct: 262 PLHPETEHMINDETLKLFKRGAYIVNTA 289 >5C1C-A nrPDB Length = 299 Score = 28.7 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 22/56 (39%) Query: 84 EEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMC 139 E V+ + FG+ + + N G S E S GW+A+ N+ + Sbjct: 157 EGAVDYIFGDASVWFGECDIVSNGAGAITASSRETSSDSGWYAIDNCNIKAASGVS 212 >4KMI-A nrPDB Length = 390 Score = 28.3 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 15/38 (39%), Gaps = 9/38 (23%) Query: 6 KGRSYLAPGLLQGQVAIVT---------GGATGIGKAI 34 + L P + G+ A+ T G GIG A+ Sbjct: 190 QRNVVLHPEFVDGKYALYTRPQDGFIDTGSGGGIGWAL 227 >4GGP-A nrPDB Length = 401 Score = 28.3 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 13/107 (12%), Positives = 29/107 (27%), Gaps = 11/107 (10%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE---------LQANLPPT 69 + +V G + G G A + G E+ S Sbjct: 51 KNVLVLGCSNGYGLA-SRITAAFGYGAATIGVSFEKAGSETKYGTPGWYNNLAFDEAAKR 109 Query: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNN-GGGQFLSP 115 + + I + ++E +++ K + +V + P Sbjct: 110 EGLYSVTIDGDAFSDEIKAQVIEEAKKKGIKFDLIVYSLASPVRTDP 156 >2D0I-A nrPDB Length = 333 Score = 28.3 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 3/58 (5%) Query: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 L G+ + G IGKAI + L+ G V + R + EL+A + Sbjct: 142 ESLYGKKVGILGMGA-IGKAIARRLIPFG--VKLYYWSRHRKVNVEKELKARYMDIDE 196 >5U9C-A nrPDB Length = 292 Score = 28.3 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 25/74 (33%), Gaps = 3/74 (4%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASR---KLERLKSAADELQANLPPTKQARVI 75 + ++TGG +G + L + NV++ R L ++ + A P Sbjct: 6 RKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHFAA 65 Query: 76 PIQCNIRNEEEVNN 89 ++ E Sbjct: 66 ETDVDLCEREPARA 79 >5L3D-A nrPDB Length = 852 Score = 28.3 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 24/61 (39%), Gaps = 4/61 (6%) Query: 17 QGQVAIV-TGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 G+V I+ +G + G A ++L G +V + + A + N A V+ Sbjct: 278 TGKVIIIGSGVS---GLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 Query: 76 P 76 Sbjct: 335 T 335 >6BMQ-A nrPDB Length = 523 Score = 28.3 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 14/26 (53%) Query: 40 ELGSNVVIASRKLERLKSAADELQAN 65 E G+ VVIA+R ER A+ + Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGK 410 >4A5O-A nrPDB Length = 286 Score = 28.3 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 16/30 (53%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASR 50 A+V G + +G+ + ELL G V + R Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHR 193 >4XRR-A nrPDB Length = 456 Score = 28.3 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 12/103 (11%), Positives = 33/103 (32%), Gaps = 7/103 (6%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 ++ G +G + L G+ VV +L+A + + Sbjct: 17 KVVIAGAGY-VGTCLAVTLAGRGAEVVAVDSDP----GTVADLRAGRCRLPEPGLAGAVR 71 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK 122 ++ + ++ D G + ++ G + E ++ + Sbjct: 72 DLAATGRLTA--STSYDPVGAADVVIVTVGTPTDAGHEMVTDQ 112 >5NUE-A nrPDB Length = 332 Score = 28.3 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 29/76 (38%), Gaps = 8/76 (10%) Query: 20 VAIVTGGATGIGKAIVKELLE---LGSN--VVIASRKLERLKSAADELQANLPPTKQARV 74 +VTG A IG A+V + LG++ V++ + AA+ L A Sbjct: 7 RVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIP---PAAEALNGVKMELIDAAF 63 Query: 75 IPIQCNIRNEEEVNNL 90 ++ + + V Sbjct: 64 PLLKGVVATTDAVEGC 79 >3HQ1-A nrPDB Length = 644 Score = 28.3 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 19/56 (33%) Query: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 ++G G A V L ++G +V + + + D A P Q Sbjct: 527 ISGSGNGPLAAFVHALADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQ 582 >1H5Y-A nrPDB Length = 253 Score = 28.3 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 24/154 (15%), Positives = 47/154 (30%), Gaps = 10/154 (6%) Query: 42 GSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFG-- 99 G+ VV+ + ++ D ++ + ++ +I E ++ Sbjct: 16 GAKVVVKGVNFQGIREVGDPVEMAVRYEEEGADEIAILDITAAPEGRATFIDSVKRVAEA 75 Query: 100 -KINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNII 158 I LV GG + L A + G V N + + +E G + Sbjct: 76 VSIPVLVG-GGVRSLEDATTLFRAGADKV-SVNTAAVRNP--QLVALLAREFGSQSTVVA 131 Query: 159 VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 + K + G T A++WA Sbjct: 132 IDAKWNGEYYEVYV--KGGREA-TGLDAVKWAKE 162 >5O2A-B nrPDB Length = 289 Score = 28.3 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 24/59 (40%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G A+V G + +G+ + ELL G + R + L+ + + + IP Sbjct: 160 GLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIP 218 >5OHX-A nrPDB Length = 504 Score = 28.0 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 37/112 (33%), Gaps = 29/112 (25%) Query: 24 TGGATGIGKAIVKE---------------------LLELGSNVV-----IASRKLERLKS 57 T G TGIG A+ L LG+ ++ + E S Sbjct: 105 TSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHIS 164 Query: 58 AADELQANLPPTKQARVIPIQCN-IRNEEEVNNLVKSTLDTFGKINFLVNNG 108 A +LQ +P + N + + + ++ GKI++LV Sbjct: 165 VAQKLQKEIPNSIILDQYTNPGNPLAHYD--QTAIEIWKQCEGKIDYLVAGA 214 >1JPH-A nrPDB Length = 388 Score = 28.0 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 35/94 (37%), Gaps = 8/94 (8%) Query: 36 KELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTL 95 +EL + G VV + K A + + + + +EEE+ LVK L Sbjct: 291 EELAQAGYEVVGLDWTVA-PKKARECVGKTVTLQGNLDPCALYA---SEEEIGQLVKQML 346 Query: 96 DTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129 D FG + + N G + + A ++ Sbjct: 347 DDFGP-HRYIANLG---HGLYPDMDPEHVGAFVD 376 >3UOG-A nrPDB Length = 363 Score = 28.0 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 26/70 (37%), Gaps = 9/70 (12%) Query: 17 QGQVAIV--TGGATGIGKAIVKELLELGSNVVIASRKLERLKSA----ADELQANLPPTK 70 G +V TGG G I K G+ V++ S E+L A AD L Sbjct: 189 AGDRVVVQGTGGVALFGLQIAK---ATGAEVIVTSSSREKLDRAFALGADHGINRLEEDW 245 Query: 71 QARVIPIQCN 80 RV + + Sbjct: 246 VERVYALTGD 255 >1ZCJ-A nrPDB Length = 463 Score = 28.0 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 24/76 (31%), Gaps = 4/76 (5%) Query: 30 IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNN 89 +G+ I +G +VV ++L +A + L Q + Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQA----SAKPKL 103 Query: 90 LVKSTLDTFGKINFLV 105 S+ ++ +V Sbjct: 104 RFSSSTKELSTVDLVV 119 >3VR3-A nrPDB Length = 600 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 16/46 (34%) Query: 31 GKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76 G I + ++G +V I + R A E+ L P Sbjct: 317 GITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEEMPGDEGYP 362 >4Y4M-A nrPDB Length = 290 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIASRKLE 53 ++ G G + L + G VV+ R L Sbjct: 62 VVIVGAGPS-GLTCARYLAKEGFKVVVLERHLA 93 >5OCM-A nrPDB Length = 291 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 32/80 (40%), Gaps = 5/80 (6%) Query: 30 IGKAIVKELLELGSNVVIASRKLERLKSAADE---LQANLPPTKQARVIPIQCNIRNEEE 86 +G+A+ L+ G + +R + A++ L ++ +A + + C + + Sbjct: 14 MGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVVVC-VSDHAA 72 Query: 87 VNNLVKSTLDTFGKINFLVN 106 V ++ D LVN Sbjct: 73 VRAVLDPLGDVLAG-RVLVN 91 >1HYE-A nrPDB Length = 313 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 41/103 (39%), Gaps = 11/103 (10%) Query: 19 QVAIVTGGATGIGKAIVKELLELGS--NVVIASR--KLERLKSAADELQANLPPTKQARV 74 +V I+ G + +G A L + ++V+ R + +L+ +++ L T+ Sbjct: 2 KVTII-GASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60 Query: 75 IPIQCN----IRNEEEVNNLVKST--LDTFGKINFLVNNGGGQ 111 I ++ + I +E +V + + +++ N Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIV 103 >1PGJ-A nrPDB Length = 478 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 11/85 (12%), Positives = 26/85 (30%), Gaps = 13/85 (15%) Query: 34 IVKELLELGSNVVIASRKLERLKS-----AADELQANLPPTKQARVIPIQCN-------- 80 + + E G V + +R + + A+ NL + Sbjct: 16 LALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALIL 75 Query: 81 IRNEEEVNNLVKSTLDTFGKINFLV 105 ++ ++ ++ F K + LV Sbjct: 76 VQAGAATDSTIEQLKKVFEKGDILV 100 >2IVE-A nrPDB Length = 478 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 29/82 (35%), Gaps = 8/82 (9%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 VA+V GG +G+ A+ L G++ V+ + A + Sbjct: 19 VAVVGGGISGL--AVAHHLRSRGTDAVLLESSARLGGAVGTHALAGYLVEQGPNSFL--- 73 Query: 80 NIRNEEEVNNLVKSTLDTFGKI 101 + E + + L+ G+I Sbjct: 74 ---DREPATRALAAALNLEGRI 92 >2DQ4-A nrPDB Length = 343 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 25/76 (32%), Gaps = 2/76 (2%) Query: 7 GRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANL 66 Y G + G+ ++TG IG + G+ ++ S + A L Sbjct: 155 HTVYAGSG-VSGKSVLITGAGP-IGLMAAMVVRASGAGPILVSDPNPYRLAFARPYADRL 212 Query: 67 PPTKQARVIPIQCNIR 82 + ++ + + Sbjct: 213 VNPLEEDLLEVVRRVT 228 >1QYC-A nrPDB Length = 308 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 34/90 (37%), Gaps = 9/90 (10%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 ++ G IG+ + K L+LG + R E S+ E L K + + Sbjct: 6 RILLIGATGYIGRHVAKASLDLGHPTFLLVR--ESTASSNSEKAQLLESFKASGANIVHG 63 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLVNNGG 109 +I + + VK ++ +++ G Sbjct: 64 SIDDHASLVEAVK-------NVDVVISTVG 86 >5YBH-A nrPDB Length = 368 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 21/64 (32%), Gaps = 4/64 (6%) Query: 30 IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNN 89 I AI + G V + L R A ++ + R P + + + Sbjct: 167 IATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYP----VSVFDSLPR 222 Query: 90 LVKS 93 L++ Sbjct: 223 LLER 226 >1MLD-A nrPDB Length = 314 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 34/132 (25%), Gaps = 31/132 (23%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA V G + GIG+ + L L + L A + Sbjct: 2 KVA-VLGASGGIGQPLSLLLKN-------------------SPLVSRLTLYDIAHTPGVA 41 Query: 79 CNIRNEEEVNNLV-----KSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 ++ + E + + D + +V G + TN T Sbjct: 42 ADLSHIETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNAT 95 Query: 134 GTFYMCKAVYSS 145 + A Sbjct: 96 IVATLTAACAQH 107 >1NHQ-A nrPDB Length = 447 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 10/29 (34%), Gaps = 1/29 (3%) Query: 21 AIVTGGATGIGKAIVKELLELGSNVVIAS 49 +V G IG + + G V + Sbjct: 152 VVVIGSGY-IGIEAAEAFAKAGKKVTVID 179 >4W5U-B nrPDB Length = 408 Score = 27.6 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 25/74 (33%), Gaps = 11/74 (14%) Query: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSK--------- 122 + C+ + NL+ + TFG + LV +P I + Sbjct: 185 PNACGLTCDSSGPDAFRNLMAALRSTFG--DELVTAAVTADGTPGGKIEATDYAGAAQYV 242 Query: 123 GWHAVLETNLTGTF 136 W+ V+ + G + Sbjct: 243 DWYNVMTYDFFGAW 256 >4QPN-A nrPDB Length = 227 Score = 27.6 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 +G+ I G TGI + G +V I L L+ +QAN+P QA+V Sbjct: 75 FRGKKVIELGAGTGI---VGILAALQGGDVTITDLPLA-LEQIQGNVQANVPAGGQAQVR 130 Query: 76 PI 77 + Sbjct: 131 AL 132 >2RIR-A nrPDB Length = 300 Score = 27.6 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%), Gaps = 3/35 (8%) Query: 29 GIGKA---IVKELLELGSNVVIASRKLERLKSAAD 60 G+G+ I + LG+NV + +R L + Sbjct: 164 GLGRTGMTIARTFAALGANVKVGARSSAHLARITE 198 >4A26-A nrPDB Length = 300 Score = 27.6 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 17/34 (50%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIAS 49 + G+ A+V G + +G + L++ + V I Sbjct: 163 MAGKRAVVLGRSNIVGAPVAALLMKENATVTIVH 196 >3ZWA-A nrPDB Length = 742 Score = 27.6 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 24/76 (31%), Gaps = 4/76 (5%) Query: 30 IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNN 89 +G+ I +G +VV ++L +A + L Q + Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQA----SAKPKL 382 Query: 90 LVKSTLDTFGKINFLV 105 S+ ++ +V Sbjct: 383 RFSSSTKELSTVDLVV 398 >2X86-A nrPDB Length = 357 Score = 27.6 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 13/24 (54%), Positives = 16/24 (66%) Query: 19 QVAIVTGGATGIGKAIVKELLELG 42 ++ IVTGGA IG IVK L + G Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKG 70 >5B1I-A nrPDB Length = 311 Score = 27.6 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 32/84 (38%), Gaps = 4/84 (4%) Query: 11 LAPGLLQGQVAIV--TGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPP 68 L G + + I+ T G TGIG A+ + L + +V+ + + L A + Sbjct: 54 LQRGRVNAKTTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEI-- 111 Query: 69 TKQARVIPIQCNIRNEEEVNNLVK 92 I+ IR E + + Sbjct: 112 VHTPSEEGIKGAIRKAEALAATIS 135 >5ZF1-A nrPDB Length = 301 Score = 27.6 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 26/76 (34%), Gaps = 9/76 (11%) Query: 18 GQVAIVTGGATGIGKAIVKELLEL---------GSNVVIASRKLERLKSAADELQANLPP 68 G+ A+V G + +G I L + V I R + K A A++ Sbjct: 158 GRNAVVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKDKLEAYCRNADIII 217 Query: 69 TKQARVIPIQCNIRNE 84 T I+ ++ Sbjct: 218 TATGLPKLIKADMVKP 233 >1HRD-A nrPDB Length = 449 Score = 27.6 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 16/163 (9%), Positives = 46/163 (28%), Gaps = 21/163 (12%) Query: 16 LQGQVAIVTGGATGIGKAIVKELLELGSN-VVIASRKLERLKSAADELQANLPPTKQARV 74 L G+ + G + K+L ELG+ V ++ + + + R Sbjct: 228 LVGKTVALAGFGN-VAWGAAKKLAELGAKAVTLSGPDGYIYDPEGITTEEKINYMLEMRA 286 Query: 75 IPIQCNIRNEEEVNNL-VKSTLDTFG-KINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 +++ + + +G K++ ++ + + ++ N+ Sbjct: 287 SGRN-KVQDYADKFGVQFFPGEKPWGQKVDIIMPCA------TQNDVDLEQAKKIVANNV 339 Query: 133 TGTFYM-----CKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVH 170 + M++ N++V Sbjct: 340 KYYIEVANMPTTNEALRFLMQQP-----NMVVAPSKAVNAGGV 377 >4I1I-A nrPDB Length = 345 Score = 27.6 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 24/68 (35%), Gaps = 1/68 (1%) Query: 12 APGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 PG + VTG A IG A+V L+ G+ + + RL L+A + Sbjct: 18 GPGSMSAVKVAVTGAAGQIGYALV-PLIARGALLGPTTPVELRLLDIEPALKALAGVEAE 76 Query: 72 ARVIPIQC 79 Sbjct: 77 LEDCAFPL 84 >2Q4B-A nrPDB Length = 253 Score = 27.6 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 29/86 (33%), Gaps = 17/86 (19%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 +VTG + G+ + K+L + GS ++ + A Sbjct: 6 TVLVTGASGRTGQIVYKKL-KEGS---------DKFVAKGLVRSAQGKEKIGGEADVFIG 55 Query: 80 NIRNEEEVNNLVKSTLDTFGKINFLV 105 +I + + +N + I+ LV Sbjct: 56 DITDADSINPAFQ-------GIDALV 74 >1F3L-A nrPDB Length = 321 Score = 27.6 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 3/51 (5%) Query: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 Y P + + +V + G TGI + + G+ VIA + E L A D Sbjct: 38 YQNPHIFKDKVVLDVGCGTGI---LSMFAAKAGAKKVIAVDQSEILYQAMD 85 >4WLE-A nrPDB Length = 340 Score = 27.6 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 34/132 (25%), Gaps = 31/132 (23%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 +VA V G + GIG+ + L L + L A + Sbjct: 28 KVA-VLGASGGIGQPLSLLLKN-------------------SPLVSRLTLYDIAHTPGVA 67 Query: 79 CNIRNEEEVNNLV-----KSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 ++ + E + + D + +V G + TN T Sbjct: 68 ADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNAT 121 Query: 134 GTFYMCKAVYSS 145 + A Sbjct: 122 IVATLTAACAQH 133 >1UN9-A nrPDB Length = 552 Score = 27.2 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 39/110 (35%), Gaps = 13/110 (11%) Query: 26 GATGIGKAIVKELLELGSN------VVIASRKLERLKSAADELQ---ANLPPTKQARVIP 76 G A V + ++ V ++S L + AA A L Sbjct: 166 AERGYNLATVLREAQYAASNTFSLGVALSSCHLPQETDAAPRHHPGHAELGMGIHGEPGA 225 Query: 77 IQCNIRNEEEVNNL-VKSTLDTF---GKINFLVNNGGGQFLSPAEHISSK 122 + +N +V NL V L G++ ++NN GG ++ I+ + Sbjct: 226 SVIDTQNSAQVVNLMVDKLLAALPETGRLAVMINNLGGVSVAEMAIITRE 275 >4J0E-A nrPDB Length = 320 Score = 27.2 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 49/140 (35%), Gaps = 10/140 (7%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA-------ADELQANLPPTKQA 72 VAIV G+ +G I + G NV++A + L A L T + Sbjct: 17 VAIV--GSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGTDKE 74 Query: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 + + + + NN+ + D I + N + A+ S ++L TN Sbjct: 75 KSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTN- 133 Query: 133 TGTFYMCKAVYSSWMKEHGG 152 T +F + K G Sbjct: 134 TSSFLLEDVAKGLQDKTRFG 153 >3K30-A nrPDB Length = 690 Score = 27.2 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 14/42 (33%), Gaps = 1/42 (2%) Query: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADE 61 +V G G + L G +VV+A + E Sbjct: 393 RVLVVGAGPS-GLEAARALGVRGYDVVLAEAGRDLGGRVTQE 433 >1HE4-A nrPDB Length = 206 Score = 27.2 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 22/74 (29%), Gaps = 11/74 (14%) Query: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 + + G G + + ++ G V + R R LP + Sbjct: 4 KKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSR-----------LPSEGPRPAHVVV 52 Query: 79 CNIRNEEEVNNLVK 92 ++ +V+ V Sbjct: 53 GDVLQAADVDKTVA 66 >1IE3-A nrPDB Length = 312 Score = 27.2 bits (59), Expect = 8.9, Method: Composition-based stats. Identities = 10/20 (50%), Positives = 13/20 (65%), Gaps = 1/20 (5%) Query: 19 QVAIVTGGATGIGKAIVKEL 38 +VA V G A GIG+A+ L Sbjct: 2 KVA-VLGAAGGIGQALALLL 20 >5A3V-A nrPDB Length = 329 Score = 27.2 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 27/61 (44%), Gaps = 6/61 (9%) Query: 17 QGQVA--IVTGGATGIGKAIVKELLE-LGSNVVIA--SRKLERLKSAADELQANLPPTKQ 71 G+ A +VT + G+G +L + ++V +R +E +KS + + + Sbjct: 153 TGKKANILVTAASGGVG-HYAVQLAKLANAHVTATCGARNIEFVKSLGADEVLDYKTPEG 211 Query: 72 A 72 A Sbjct: 212 A 212 >2Z0M-A nrPDB Length = 337 Score = 27.2 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 42/99 (42%), Gaps = 8/99 (8%) Query: 8 RSYLAPGLLQGQVAIV---TGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQA 64 +S P +LQG+ +V TG A +LELG ++ + E + A ++ Sbjct: 21 QSKTIPLMLQGKNVVVRAKTGSGKT--AAYAIPILELGMKSLVVTPTRELTRQVASHIR- 77 Query: 65 NLPPTKQARVIPIQCNIRNEEEVNNL--VKSTLDTFGKI 101 ++ +V + + + ++N + + T G++ Sbjct: 78 DIGRYMDTKVAEVYGGMPYKAQINRVRNADIVVATPGRL 116 >2ZJ1-A nrPDB Length = 495 Score = 27.2 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 16/111 (14%), Positives = 37/111 (33%), Gaps = 27/111 (24%) Query: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 G+ ++ G +GK + + G+ V + + P + + Sbjct: 275 GKKVLICGYGD-VGKGCAEAMKGQGARVSVT----------------EIDPINALQAMME 317 Query: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVL 128 ++ + + G + +V G + + EHI + HA+L Sbjct: 318 GFDV----------VTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAIL 358 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.148 0.410 Lambda K H 0.267 0.0454 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,079,495 Number of Sequences: 36641 Number of extensions: 580055 Number of successful extensions: 3705 Number of sequences better than 10.0: 448 Number of HSP's better than 10.0 without gapping: 424 Number of HSP's successfully gapped in prelim test: 231 Number of HSP's that attempted gapping in prelim test: 2235 Number of HSP's gapped (non-prelim): 699 length of query: 303 length of database: 10,336,785 effective HSP length: 97 effective length of query: 206 effective length of database: 6,782,608 effective search space: 1397217248 effective search space used: 1397217248 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.2 bits)