BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BXJ9 (866 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6C95-A nrPDB 1790 0.0 5NNP-A nrPDB 509 e-144 4KVO-A nrPDB 462 e-130 4HNX-A nrPDB 316 2e-86 5DSE-A nrPDB 35 0.096 5LVV-A nrPDB 34 0.21 3EFZ-A nrPDB 33 0.61 3TMG-A nrPDB 32 0.96 2OKV-A nrPDB 32 1.1 5UDI-A nrPDB 31 2.4 2EB5-A nrPDB 31 2.6 6EM5-I nrPDB 30 3.4 6B2W-A nrPDB 30 3.9 2GW1-A nrPDB 30 4.7 2YXE-A nrPDB 30 4.8 4WSE-A nrPDB 30 6.6 5XJC-J nrPDB 29 7.5 >6C95-A nrPDB Length = 866 Score = 1790 bits (4635), Expect = 0.0, Method: Compositional matrix adjust. Identities = 866/866 (100%), Positives = 866/866 (100%) Query: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG Sbjct: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 Query: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL Sbjct: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 Query: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT Sbjct: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 Query: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL Sbjct: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 Query: 241 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF 300 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF Sbjct: 241 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF 300 Query: 301 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN 360 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN Sbjct: 301 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN 360 Query: 361 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH 420 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH Sbjct: 361 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH 420 Query: 421 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN 480 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN Sbjct: 421 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN 480 Query: 481 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD 540 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD Sbjct: 481 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD 540 Query: 541 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR 600 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR Sbjct: 541 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR 600 Query: 601 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF 660 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF Sbjct: 601 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF 660 Query: 661 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV 720 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV Sbjct: 661 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV 720 Query: 721 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ 780 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ Sbjct: 721 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ 780 Query: 781 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP 840 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP Sbjct: 781 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP 840 Query: 841 PGYEEDMKITVNGDSSAEAEELANEI 866 PGYEEDMKITVNGDSSAEAEELANEI Sbjct: 841 PGYEEDMKITVNGDSSAEAEELANEI 866 >5NNP-A nrPDB Length = 745 Score = 509 bits (1310), Expect = e-144, Method: Compositional matrix adjust. Identities = 300/756 (39%), Positives = 440/756 (58%), Gaps = 23/756 (3%) Query: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILS-NPKFAEHGETLAMKGLTLNCL 59 M L +E LF+ ++R YE KQY+ GLK +QIL NPK HG+T++MK L LN Sbjct: 1 MGPQPLSTREANLFRTVIRHYEDKQYKRGLKAAEQILKKNPK---HGDTMSMKALILNAQ 57 Query: 60 GKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRD 119 GK EEA+ L + L D+KS++CWHVYG+L R++K +DEAIK Y+ ALK + ++ QI RD Sbjct: 58 GKTEEAFALAKEALTIDMKSYICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRD 117 Query: 120 LSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQ 179 L++LQIQMRD GY ++R +L+ RP R +W AIAYHL + E A IL + K+ Sbjct: 118 LAVLQIQMRDYAGYVQSRLNMLKARPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLT 177 Query: 180 TSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCR 239 T P K D E+SE LLY+N ++ E G AL+HL T K D+LAV E + L +L R Sbjct: 178 TPPPKTDLEHSEALLYKNTIIAERGDIERALQHLETDCKHCLDRLAVMELRASYLSKLAR 237 Query: 240 LEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLK--IYEEAWTKYPRGLVPRRLP 297 ++AA YR L +RNPE+ YYKGL AL + E + +Y+E KYPR +RLP Sbjct: 238 KDEAAKAYRALLDRNPEHMDYYKGLISALDISADDEEAQKAVYDEYAAKYPRSDAAKRLP 297 Query: 298 LNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCR 357 LNFLSGE+F+ +L + F KG P F L+ LY D K + L Y + R Sbjct: 298 LNFLSGERFRTTAKAYLTLMFDKGVPSTFANLKHLYSDSFKKETLASLAEEYLNEYVNAR 357 Query: 358 LFNPND-----DGKEEPPTTLLWVQYYLAQHYDKIGQPSI--ALEYINTAIESTPTLIEL 410 P+D DG + L YYLAQHY+ + ALEY+ AIE P ++ Sbjct: 358 ---PSDNQADGDGSKGKGAAL----YYLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDF 410 Query: 411 FLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR 470 + KA+I+KH G++ +AA MD A++LD DR+INSK AKY L+ N ++A FTR Sbjct: 411 HMTKARIFKHQGDLAKAAETMDYARSLDPKDRYINSKAAKYQLRNNENEKALATMGLFTR 470 Query: 471 EGTSA--VENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTY 528 T+ + +L +MQC+WF TE +A++ ALK+ H + F +DQFDFH++ Sbjct: 471 AETAGGPLADLTDMQCIWFLTEDGEAWQRRGNTALALKRYHTVFSIFDTWQEDQFDFHSF 530 Query: 529 CMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMS 588 +RK +R+YVD+++ ED LR+HPFYF+AA A+ +YL ++D P + N + + AN + Sbjct: 531 SLRKGQIRAYVDMVRWEDRLREHPFYFRAALDAVNLYLSMYDKPQS-ANGANGTEAANPN 589 Query: 589 DKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLA 648 ++ + + ++A+K+AQ E + KQ N+ + +E+I ++ EKLA Sbjct: 590 GEDAAEKKKAAKKARKEAQKAEREAAERAAKQDPNKPGAQKGKEEDIKKKDDDPNGEKLA 649 Query: 649 KVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWL 708 + PL +A+KFL + I+ + FE+Y RK+K+LL L+ +K A AID +HP + Sbjct: 650 ATKDPLGDAMKFLNYILQFSPKNIDGQIAGFEVYIRKKKYLLALRCLKAASAIDKNHPKV 709 Query: 709 HECMIRLFNTAVCESKDLSDTVRTVLKQEMNRLFGA 744 E +L ++ +R V++ E+ + GA Sbjct: 710 LEQAAKLRKIVSSALDSMAPKLREVIQAELVGVPGA 745 >4KVO-A nrPDB Length = 731 Score = 462 bits (1189), Expect = e-130, Method: Compositional matrix adjust. Identities = 272/701 (38%), Positives = 401/701 (57%), Gaps = 21/701 (2%) Query: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 M V L PKE LF+ L+CYE KQY+ GLK + +L + EHGE+LA+KG+ L+ LG Sbjct: 1 MAKVQLSPKEITLFRTALKCYETKQYKKGLKAIEPLLE--RHPEHGESLAIKGILLHSLG 58 Query: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 +E Y+ VR GLRND+ S VCWH++GL+ R+DK Y +A KCY NA K +K+N +LRDL Sbjct: 59 NTKEGYDNVRLGLRNDVGSGVCWHIFGLISRADKDYVQAAKCYINAHKLEKNNSSLLRDL 118 Query: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 +LLQ Q+R + +TR LLQ P RA+W A+A L +Y A KI++ F T Sbjct: 119 ALLQSQLRQYKALADTRNALLQDNPGVRANWSALAVAQFLRGEYASAYKIVDAFESTINQ 178 Query: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 E SE +L+ N V+ + +A +HL + EK++ D++A ET+ E L L ++ Sbjct: 179 GVPVDTQEESEAMLFMNLVILKKDGVEDAYKHLLSIEKKVLDRVAFLETRAEYELYLSKM 238 Query: 241 EDAADVYRGLQERNPENWAYYKGLEKAL-------KPANMLERLKIYEEAWTKYPRGLVP 293 E+A L +RNP+N YY L++A K + E L +Y + +YP+ P Sbjct: 239 EEAKSTIYLLLDRNPDNHQYYYNLQRAYGYEDASGKVLDSAEWLNLYSQLAKRYPKSECP 298 Query: 294 RRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSL 353 RLPL L G++F +D +LR +G P VF ++SLYKD +K ++E+LV Y +SL Sbjct: 299 TRLPLEKLEGDEFLTHVDLYLRKKLKRGIPSVFVDVKSLYKDTKKCKVVEDLVSKYASSL 358 Query: 354 KSCRLFNPNDDGKE-EPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFL 412 + F+ +DD + E PTTLLW Y+LAQH+D +G+ A +Y++ AI+ TPTL+ELF+ Sbjct: 359 STTNKFSEDDDNSQIEIPTTLLWTYYFLAQHFDHVGELEKAEKYVDLAIDHTPTLVELFM 418 Query: 413 VKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREG 472 KA+I KH G ++ A MD A+ LD DRFIN KCAKYML+ + + A + S FTR Sbjct: 419 TKARISKHKGELQTAMEIMDHARKLDLQDRFINGKCAKYMLRNDENELAAKTVSLFTRNE 478 Query: 473 T--SAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCM 530 AV +L +MQC+W+ E +++ KF ALK+ + + F DDQFDFH + Sbjct: 479 AVGGAVGDLADMQCLWYMLEDGKSFARQKKFALALKRFSTVFKIFDTWADDQFDFHFFAF 538 Query: 531 RKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDK 590 RK +LR+Y+DL+ ED + P + +AA+ +IEIY L D P + + D +S Sbjct: 539 RKGSLRTYLDLMSWEDSVYDDPSFREAAQGSIEIYFALFDLPFAKYSPKL-PDFEKLSSG 597 Query: 591 ELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGP---KEELIPEKL 647 E+ + K+ + K + + + AEK K+ + K +D G P E+ + E L Sbjct: 598 EINEEEEKKIYKKLKKDLSKRLERAEKLKEADKSRAKSED-----GMPVKYDEDPLGENL 652 Query: 648 AKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKF 688 PL+EA K L L ++ A ++Y R + F Sbjct: 653 VATSEPLKEAQKCLEKLLPYGDKNPSAYILAAQLYTRLKNF 693 >4HNX-A nrPDB Length = 863 Score = 316 bits (810), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 231/744 (31%), Positives = 380/744 (51%), Gaps = 81/744 (10%) Query: 9 KENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEL 68 KEN F L+ YE KQY+ LK IL K H ++LA+KGL L +G+K++A Sbjct: 19 KENDQFLEALKLYEGKQYKKSLKLLDAILK--KDGSHVDSLALKGLDLYSVGEKDDAASY 76 Query: 69 VRRGLR---NDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQI 125 V +R S +C HV G+ R+ K+Y E+IK + AL N QI RDL+ LQ Sbjct: 77 VANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQS 136 Query: 126 QMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTS-PDK 184 Q+ D + +R + + RA+W A+A + + + A L +F K + D Sbjct: 137 QIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDS 196 Query: 185 VDYEYSELLLYQNQVLREAGL-----YREALEHLCTYEKQICDKLAVEETKGELLLQLCR 239 YE+SE L+Y+N ++ +A + L+HL E + DK + E K + ++L + Sbjct: 197 EKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQ 256 Query: 240 LEDAADVYRGLQERNPENWAYYKGLEKAL--KPANMLERLKIYEEAWTKYPRGLVPRRLP 297 L+DA+ VYR L +RNP+N+ YYK LE +L + N L++ +Y + YPR P+ +P Sbjct: 257 LKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKK-ALYGKLEQFYPRCEPPKFIP 315 Query: 298 LNFLSG-EKFKECLDKFLRMNFSKGCPPVFNTLRSLY-KDKEKVA-IIEELVVGYETSLK 354 L FL E+ + L +++ +G P F+ ++ LY + K KV+ ++E++V+ Y + L Sbjct: 316 LTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGL- 374 Query: 355 SCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVK 414 +P D P +W YYL+QH+ + A EYI+ A++ TPTL+E +++K Sbjct: 375 -----DPTQD-----PIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILK 424 Query: 415 AKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR--EG 472 A+I KH G + AA ++E + LD DRFIN K KY L+AN I +A E+ S FT+ + Sbjct: 425 ARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDS 484 Query: 473 TSAVENLNEMQCMWFQTECAQAYKAM--------------------------------NK 500 + +++L+ ++ WF E A+AY + N+ Sbjct: 485 VNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQ 544 Query: 501 F------GEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFY 554 + G ALK+ + I + + + DDQ DFH+YCMRK T R+Y+++L+ L P Y Sbjct: 545 WLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMY 604 Query: 555 FKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKN 614 +A + A ++Y ++HD+ L + ++D+ + + E++ +KKA+ E N Sbjct: 605 VRAMKEASKLYFQMHDDRL-----KRKSDSLDENSDEIQNNGQNSSSQKKKAKKEAAAMN 659 Query: 615 AEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIE 673 KE + ++ D D ++ G EKL + TP+E+ A +F V+ Sbjct: 660 KRKETEAKSVAAYPSDQDNDVFG-------EKLIETSTPMEDFATEFYNNYSMQVREDER 712 Query: 674 THLFAFEIYFRKEKFLLMLQSVKR 697 ++ FE +R K L S+ + Sbjct: 713 DYILDFEFNYRIGKLALCFASLNK 736 >5DSE-A nrPDB Length = 837 Score = 35.4 bits (80), Expect = 0.096, Method: Compositional matrix adjust. Identities = 31/143 (21%), Positives = 62/143 (43%), Gaps = 11/143 (7%) Query: 331 SLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQP 390 S++ + +E+ + +SL+S + G P TL + + A+ Y IG+P Sbjct: 651 SVHATSVAASRVEQALSEVASSLQS----SAPKQGPLHPWMTLAQIWLHAAEVYIGIGKP 706 Query: 391 SIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTAD-------RF 443 + A A P + ++ +I + G++ EA RW +EA A+ Sbjct: 707 AEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLAL 766 Query: 444 INSKCAKYMLKANLIKEAEEMCS 466 I + +Y L ++++A ++ S Sbjct: 767 ILHQLGRYSLAEKILRDAVQVNS 789 >5LVV-A nrPDB Length = 749 Score = 34.3 bits (77), Expect = 0.21, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 127 MRDLEGY-RETRYQLLQLRPAQ-RASWIGY-AIAYHLLEDYEMAAKILEEFRKTQQTSPD 183 + ++ GY + R +L LRPA +A W+GY + L DY + Q+TSP Sbjct: 339 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIIT---------DQETSPA 389 Query: 184 KVDYEYSELLLY 195 +V +YSE L Y Sbjct: 390 EVAEQYSEKLAY 401 >3EFZ-A nrPDB Length = 268 Score = 32.7 bits (73), Expect = 0.61, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 9/76 (11%) Query: 332 LYKDKEKVAIIEELVVGYETSLKSCRLF---NPNDDGKEEPPTTLLWVQYYLAQHYDKIG 388 + KD+EK I++ V YE +L+ R F P+D P L + Y YD +G Sbjct: 158 ILKDEEKNQCIKQAVEFYEDALQRERSFLEKYPSD------PLYLATILNYTILKYDLLG 211 Query: 389 QPSIALEYINTAIEST 404 P A+++ N AI++ Sbjct: 212 NPEGAMKFANRAIQAA 227 >3TMG-A nrPDB Length = 280 Score = 32.3 bits (72), Expect = 0.96, Method: Composition-based stats. Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 6/66 (9%) Query: 59 LGKKEEAYELVRRGLRND------LKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKD 112 +G E + LVR GL ND + H W +L DK E K YRNA+++ + Sbjct: 203 MGGIESVHTLVRLGLENDDFDAYYVFDHFYWSDDLILPLMDKNDKEPGKEYRNAVEFVEK 262 Query: 113 NLQILR 118 N +I++ Sbjct: 263 NKEIVK 268 >2OKV-A nrPDB Length = 209 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 8/68 (11%) Query: 565 YLKLH---DNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQ 621 Y+++H D P+T E + TA K+L KL +Q+R +K K + ++ Sbjct: 130 YMQVHIQNDGPVTIELESPAPGTATSDPKQLSKLEKQQQRKEKT-----RAKGPSESSKE 184 Query: 622 RNQKKKKD 629 RN +K+D Sbjct: 185 RNTPRKED 192 >5UDI-A nrPDB Length = 479 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 371 TTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYK-HAGNIKEAAR 429 ++ +V Y A+ Y + G ALE + A++ TPT + L YK IKEA + Sbjct: 249 SSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATK 308 Query: 430 WMDEAQALDTADRFINS 446 Q + D+ I S Sbjct: 309 GQPRGQNREKLDKMIRS 325 >2EB5-A nrPDB Length = 267 Score = 30.8 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 3/57 (5%) Query: 182 PDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLA---VEETKGELLL 235 PD++D + L+Y+N V+ E G+ L H + +KLA V+ G+++L Sbjct: 180 PDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIIL 236 >6EM5-I nrPDB Length = 663 Score = 30.4 bits (67), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/50 (46%), Positives = 33/50 (66%), Gaps = 10/50 (20%) Query: 585 ANMSDKELKK-----LRNKQRRAQKKA-QIEEEKKNAEK----EKQQRNQ 624 N+S +LKK L KQR+A+K+ QIEEE +NAE+ E+++RNQ Sbjct: 354 GNVSAPKLKKKDRVHLSKKQRKARKEMQQIEEEMRNAEQAVSAEERERNQ 403 >6B2W-A nrPDB Length = 333 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/62 (25%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 127 MRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVD 186 ++ + + E Y +L L P +++ W Y +L+ Y+ K++ EF+K +P + D Sbjct: 10 IKSIPEWSEQEYLMLSL-PHEKSDWNPYL--EEILQSYKEFVKVVSEFQKVLLIAPKQSD 66 Query: 187 YE 188 +E Sbjct: 67 FE 68 >2GW1-A nrPDB Length = 514 Score = 30.0 bits (66), Expect = 4.7, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 93 DKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRP 145 +KKYD+AIK Y AL+ +D + +LS + + DL+ E + L+L+P Sbjct: 19 NKKYDDAIKYYNWALELKEDPV-FYSNLSACYVSVGDLKKVVEMSTKALELKP 70 >2YXE-A nrPDB Length = 215 Score = 30.0 bits (66), Expect = 4.8, Method: Composition-based stats. Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Query: 608 IEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKL---AKVETPLE 655 +EE+KK ++ + K K D + P+EE +PE L A V+TPLE Sbjct: 3 LEEQKKAVIEKLIREGYIKSKRVIDALLKVPREEFLPEHLKEYAYVDTPLE 53 >4WSE-A nrPDB Length = 584 Score = 29.6 bits (65), Expect = 6.6, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 8/60 (13%) Query: 299 NFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEEL----VVGYETSLK 354 NF++ F E + +N+ + +N LR + +DKEK+++ E GY T +K Sbjct: 279 NFIANVPFSELI----SVNYREDVKNTYNFLRMIVEDKEKISVDEYFPLFQFTGYSTVIK 334 >5XJC-J nrPDB Length = 848 Score = 29.3 bits (64), Expect = 7.5, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 123 LQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILE-EFRKTQQTS 181 L++Q+R+ + R+ + L+ P SWI +A +L D + A I E + + Sbjct: 615 LELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDM 674 Query: 182 PDKVDYEYSELLLYQNQVLREAGLYREALE 211 P+ + Y + + Q + R LYR L+ Sbjct: 675 PEVLWKSYIDFEIEQEETERTRNLYRRLLQ 704 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6C95-A nrPDB 1366 0.0 5NNP-A nrPDB 1003 0.0 4KVO-A nrPDB 946 0.0 4HNX-A nrPDB 847 0.0 Sequences not found previously or not previously below threshold: 1W3B-A nrPDB 53 6e-07 5G04-F nrPDB 44 4e-04 5LVV-A nrPDB 42 8e-04 5OJF-A nrPDB 41 0.002 5WQL-B nrPDB 41 0.002 6AHD-N nrPDB 41 0.003 5DSE-A nrPDB 41 0.003 2GW1-A nrPDB 40 0.005 4JA9-A nrPDB 40 0.005 5OJ8-A nrPDB 39 0.008 6B85-J nrPDB 39 0.009 5MGX-E nrPDB 39 0.010 2Y4T-A nrPDB 39 0.012 3NF1-A nrPDB 39 0.012 6ICZ-I nrPDB 38 0.014 3ZFW-A nrPDB 37 0.024 5ZVW-A nrPDB 37 0.038 6FUZ-A nrPDB 37 0.043 5UDI-A nrPDB 36 0.052 5FZQ-A nrPDB 36 0.054 6FRK-r nrPDB 36 0.072 1IHG-A nrPDB 36 0.11 5G04-X nrPDB 35 0.17 5YFP-B nrPDB 34 0.20 5JJT-A nrPDB 34 0.24 3GDB-A nrPDB 34 0.28 5XJC-J nrPDB 34 0.34 3JCM-G nrPDB 32 0.79 1F5N-A nrPDB 32 0.90 5G05-C nrPDB 31 2.1 6AF0-A nrPDB 31 2.3 6F91-A nrPDB 31 3.5 3ATP-A nrPDB 31 3.5 6FAI-j nrPDB 31 3.5 6GMH-U nrPDB 31 3.6 6FES-A nrPDB 30 4.0 5LJ5-s nrPDB 30 4.8 6FO1-G nrPDB 30 5.4 4HOQ-A nrPDB 29 6.6 5EFR-A nrPDB 29 6.8 1VPM-A nrPDB 29 8.0 1A17-A nrPDB 29 8.0 5JWG-A nrPDB 29 9.5 >6C95-A nrPDB Length = 866 Score = 1366 bits (3535), Expect = 0.0, Method: Composition-based stats. Identities = 866/866 (100%), Positives = 866/866 (100%) Query: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG Sbjct: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 Query: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL Sbjct: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 Query: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT Sbjct: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 Query: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL Sbjct: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 Query: 241 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF 300 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF Sbjct: 241 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF 300 Query: 301 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN 360 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN Sbjct: 301 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN 360 Query: 361 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH 420 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH Sbjct: 361 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH 420 Query: 421 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN 480 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN Sbjct: 421 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN 480 Query: 481 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD 540 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD Sbjct: 481 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD 540 Query: 541 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR 600 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR Sbjct: 541 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR 600 Query: 601 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF 660 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF Sbjct: 601 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF 660 Query: 661 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV 720 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV Sbjct: 661 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV 720 Query: 721 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ 780 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ Sbjct: 721 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ 780 Query: 781 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP 840 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP Sbjct: 781 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP 840 Query: 841 PGYEEDMKITVNGDSSAEAEELANEI 866 PGYEEDMKITVNGDSSAEAEELANEI Sbjct: 841 PGYEEDMKITVNGDSSAEAEELANEI 866 >5NNP-A nrPDB Length = 745 Score = 1003 bits (2594), Expect = 0.0, Method: Composition-based stats. Identities = 296/752 (39%), Positives = 438/752 (58%), Gaps = 15/752 (1%) Query: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 M L +E LF+ ++R YE KQY+ GLK +QIL K +HG+T++MK L LN G Sbjct: 1 MGPQPLSTREANLFRTVIRHYEDKQYKRGLKAAEQILK--KNPKHGDTMSMKALILNAQG 58 Query: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 K EEA+ L + L D+KS++CWHVYG+L R++K +DEAIK Y+ ALK + ++ QI RDL Sbjct: 59 KTEEAFALAKEALTIDMKSYICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDL 118 Query: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 ++LQIQMRD GY ++R +L+ RP R +W AIAYHL + E A IL + K+ T Sbjct: 119 AVLQIQMRDYAGYVQSRLNMLKARPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTT 178 Query: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 P K D E+SE LLY+N ++ E G AL+HL T K D+LAV E + L +L R Sbjct: 179 PPPKTDLEHSEALLYKNTIIAERGDIERALQHLETDCKHCLDRLAVMELRASYLSKLARK 238 Query: 241 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLK--IYEEAWTKYPRGLVPRRLPL 298 ++AA YR L +RNPE+ YYKGL AL + E + +Y+E KYPR +RLPL Sbjct: 239 DEAAKAYRALLDRNPEHMDYYKGLISALDISADDEEAQKAVYDEYAAKYPRSDAAKRLPL 298 Query: 299 NFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRL 358 NFLSGE+F+ +L + F KG P F L+ LY D K + L Y + R Sbjct: 299 NFLSGERFRTTAKAYLTLMFDKGVPSTFANLKHLYSDSFKKETLASLAEEYLNEYVNARP 358 Query: 359 FN--PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSI--ALEYINTAIESTPTLIELFLVK 414 + + DG + L YYLAQHY+ + ALEY+ AIE P ++ + K Sbjct: 359 SDNQADGDGSKGKGAAL----YYLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDFHMTK 414 Query: 415 AKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTS 474 A+I+KH G++ +AA MD A++LD DR+INSK AKY L+ N ++A FTR T+ Sbjct: 415 ARIFKHQGDLAKAAETMDYARSLDPKDRYINSKAAKYQLRNNENEKALATMGLFTRAETA 474 Query: 475 A--VENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRK 532 + +L +MQC+WF TE +A++ ALK+ H + F +DQFDFH++ +RK Sbjct: 475 GGPLADLTDMQCIWFLTEDGEAWQRRGNTALALKRYHTVFSIFDTWQEDQFDFHSFSLRK 534 Query: 533 ITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKEL 592 +R+YVD+++ ED LR+HPFYF+AA A+ +YL ++D P + N + + AN + ++ Sbjct: 535 GQIRAYVDMVRWEDRLREHPFYFRAALDAVNLYLSMYDKPQS-ANGANGTEAANPNGEDA 593 Query: 593 KKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVET 652 + + ++A+K+AQ E + KQ N+ + +E+I ++ EKLA + Sbjct: 594 AEKKKAAKKARKEAQKAEREAAERAAKQDPNKPGAQKGKEEDIKKKDDDPNGEKLAATKD 653 Query: 653 PLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECM 712 PL +A+KFL + I+ + FE+Y RK+K+LL L+ +K A AID +HP + E Sbjct: 654 PLGDAMKFLNYILQFSPKNIDGQIAGFEVYIRKKKYLLALRCLKAASAIDKNHPKVLEQA 713 Query: 713 IRLFNTAVCESKDLSDTVRTVLKQEMNRLFGA 744 +L ++ +R V++ E+ + GA Sbjct: 714 AKLRKIVSSALDSMAPKLREVIQAELVGVPGA 745 >4KVO-A nrPDB Length = 731 Score = 946 bits (2445), Expect = 0.0, Method: Composition-based stats. Identities = 274/714 (38%), Positives = 407/714 (57%), Gaps = 21/714 (2%) Query: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 M V L PKE LF+ L+CYE KQY+ GLK + +L + EHGE+LA+KG+ L+ LG Sbjct: 1 MAKVQLSPKEITLFRTALKCYETKQYKKGLKAIEPLLE--RHPEHGESLAIKGILLHSLG 58 Query: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 +E Y+ VR GLRND+ S VCWH++GL+ R+DK Y +A KCY NA K +K+N +LRDL Sbjct: 59 NTKEGYDNVRLGLRNDVGSGVCWHIFGLISRADKDYVQAAKCYINAHKLEKNNSSLLRDL 118 Query: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 +LLQ Q+R + +TR LLQ P RA+W A+A L +Y A KI++ F T Sbjct: 119 ALLQSQLRQYKALADTRNALLQDNPGVRANWSALAVAQFLRGEYASAYKIVDAFESTINQ 178 Query: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 E SE +L+ N V+ + +A +HL + EK++ D++A ET+ E L L ++ Sbjct: 179 GVPVDTQEESEAMLFMNLVILKKDGVEDAYKHLLSIEKKVLDRVAFLETRAEYELYLSKM 238 Query: 241 EDAADVYRGLQERNPENWAYYKGLEKAL-------KPANMLERLKIYEEAWTKYPRGLVP 293 E+A L +RNP+N YY L++A K + E L +Y + +YP+ P Sbjct: 239 EEAKSTIYLLLDRNPDNHQYYYNLQRAYGYEDASGKVLDSAEWLNLYSQLAKRYPKSECP 298 Query: 294 RRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSL 353 RLPL L G++F +D +LR +G P VF ++SLYKD +K ++E+LV Y +SL Sbjct: 299 TRLPLEKLEGDEFLTHVDLYLRKKLKRGIPSVFVDVKSLYKDTKKCKVVEDLVSKYASSL 358 Query: 354 KSCRLFNPNDDGKE-EPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFL 412 + F+ +DD + E PTTLLW Y+LAQH+D +G+ A +Y++ AI+ TPTL+ELF+ Sbjct: 359 STTNKFSEDDDNSQIEIPTTLLWTYYFLAQHFDHVGELEKAEKYVDLAIDHTPTLVELFM 418 Query: 413 VKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREG 472 KA+I KH G ++ A MD A+ LD DRFIN KCAKYML+ + + A + S FTR Sbjct: 419 TKARISKHKGELQTAMEIMDHARKLDLQDRFINGKCAKYMLRNDENELAAKTVSLFTRNE 478 Query: 473 T--SAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCM 530 AV +L +MQC+W+ E +++ KF ALK+ + + F DDQFDFH + Sbjct: 479 AVGGAVGDLADMQCLWYMLEDGKSFARQKKFALALKRFSTVFKIFDTWADDQFDFHFFAF 538 Query: 531 RKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDK 590 RK +LR+Y+DL+ ED + P + +AA+ +IEIY L D P + + D +S Sbjct: 539 RKGSLRTYLDLMSWEDSVYDDPSFREAAQGSIEIYFALFDLPFAKYSPKL-PDFEKLSSG 597 Query: 591 ELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGP---KEELIPEKL 647 E+ + K+ + K + + + AEK K+ + K +D G P E+ + E L Sbjct: 598 EINEEEEKKIYKKLKKDLSKRLERAEKLKEADKSRAKSED-----GMPVKYDEDPLGENL 652 Query: 648 AKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAI 701 PL+EA K L L ++ A ++Y R + F + +++A I Sbjct: 653 VATSEPLKEAQKCLEKLLPYGDKNPSAYILAAQLYTRLKNFDTASKYLEQAKVI 706 >4HNX-A nrPDB Length = 863 Score = 847 bits (2188), Expect = 0.0, Method: Composition-based stats. Identities = 236/796 (29%), Positives = 394/796 (49%), Gaps = 81/796 (10%) Query: 9 KENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEL 68 KEN F L+ YE KQY+ LK IL K H ++LA+KGL L +G+K++A Sbjct: 19 KENDQFLEALKLYEGKQYKKSLKLLDAILK--KDGSHVDSLALKGLDLYSVGEKDDAASY 76 Query: 69 VRRGLR---NDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQI 125 V +R S +C HV G+ R+ K+Y E+IK + AL N QI RDL+ LQ Sbjct: 77 VANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQS 136 Query: 126 QMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTS-PDK 184 Q+ D + +R + + RA+W A+A + + + A L +F K + D Sbjct: 137 QIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDS 196 Query: 185 VDYEYSELLLYQNQVLREAGL-----YREALEHLCTYEKQICDKLAVEETKGELLLQLCR 239 YE+SE L+Y+N ++ +A + L+HL E + DK + E K + ++L + Sbjct: 197 EKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQ 256 Query: 240 LEDAADVYRGLQERNPENWAYYKGLEKAL--KPANMLERLKIYEEAWTKYPRGLVPRRLP 297 L+DA+ VYR L +RNP+N+ YYK LE +L + N L++ +Y + YPR P+ +P Sbjct: 257 LKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKK-ALYGKLEQFYPRCEPPKFIP 315 Query: 298 LNFLSG-EKFKECLDKFLRMNFSKGCPPVFNTLRSLY-KDKEKVA-IIEELVVGYETSLK 354 L FL E+ + L +++ +G P F+ ++ LY + K KV+ ++E++V+ Y + L Sbjct: 316 LTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGL- 374 Query: 355 SCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVK 414 +P D P +W YYL+QH+ + A EYI+ A++ TPTL+E +++K Sbjct: 375 -----DPTQD-----PIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILK 424 Query: 415 AKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR--EG 472 A+I KH G + AA ++E + LD DRFIN K KY L+AN I +A E+ S FT+ + Sbjct: 425 ARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDS 484 Query: 473 TSAVENLNEMQCMWFQTECAQAYKAM--------------------------------NK 500 + +++L+ ++ WF E A+AY + N+ Sbjct: 485 VNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQ 544 Query: 501 F------GEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFY 554 + G ALK+ + I + + + DDQ DFH+YCMRK T R+Y+++L+ L P Y Sbjct: 545 WLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMY 604 Query: 555 FKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKN 614 +A + A ++Y ++HD+ L + ++D+ + + E++ +KKA+ E N Sbjct: 605 VRAMKEASKLYFQMHDDRL-----KRKSDSLDENSDEIQNNGQNSSSQKKKAKKEAAAMN 659 Query: 615 AEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIE 673 KE + ++ D D ++ EKL + TP+E+ A +F V+ Sbjct: 660 KRKETEAKSVAAYPSDQDNDVF-------GEKLIETSTPMEDFATEFYNNYSMQVREDER 712 Query: 674 THLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCESKDLSDTVRTV 733 ++ FE +R K L S+ + + L M + A ++ V Sbjct: 713 DYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHATRNDTPFDPILKKV 772 Query: 734 LKQEMNRLFGATNPKN 749 + + + + + P N Sbjct: 773 VTKSLEKEYSENFPLN 788 >1W3B-A nrPDB Length = 388 Score = 52.8 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 42/234 (17%), Positives = 81/234 (34%), Gaps = 8/234 (3%) Query: 53 GLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKD 112 G L LG+ EEA + + V W G + + + AI + A+ D + Sbjct: 142 GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN 201 Query: 113 NLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILE 172 L +L + + R + + L L P A Y+ ++A ++ Sbjct: 202 FLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLA---ID 258 Query: 173 EFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGE 232 +R+ + P + + L+E G EA + T + Sbjct: 259 TYRRAIELQP-----HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLAN 313 Query: 233 LLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTK 286 + + +E+A +YR E PE A + L L+ L+ ++ + + Sbjct: 314 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 367 Score = 49.4 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 77/374 (20%), Positives = 130/374 (34%), Gaps = 34/374 (9%) Query: 95 KYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGY 154 ++ A + + + DN +L LS + Q R L+ ++ P ++ Sbjct: 14 DFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNL 73 Query: 155 AIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQV--LREAGLYREALEH 212 Y + A +E +R + PD +D Y N L AG A++ Sbjct: 74 GNVYKERGQLQEA---IEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQA 123 Query: 213 LCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPAN 272 + + D V G LL L RLE+A Y E P + L Sbjct: 124 YVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 183 Query: 273 MLERLKI--YEEAWTKYPRGLVPRRLPLNFLSGEK-FKECLDKFLR-MNFSKGCPPVFNT 328 + L I +E+A T P L N L + F + +LR ++ S V Sbjct: 184 EI-WLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN 242 Query: 329 LRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIG 388 L +Y ++ + +L + + P+ LA + G Sbjct: 243 LACVYYEQG----LIDLAIDTYRRAIELQPHFPD-------------AYCNLANALKEKG 285 Query: 389 QPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKC 448 + A + NTA+ PT + A I + GNI+EA R +A + +S Sbjct: 286 SVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNL 345 Query: 449 AKYMLKANLIKEAE 462 A + + ++EA Sbjct: 346 ASVLQQQGKLQEAL 359 >5G04-F nrPDB Length = 824 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 32/215 (14%), Positives = 80/215 (37%), Gaps = 10/215 (4%) Query: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 + + A + +R ++ D + + G ++ D+A+ C+RNA++ + + L Sbjct: 582 EHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGL 641 Query: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 ++ + + L + P + H + + K L+ K Sbjct: 642 GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA---LKKSEKALDTLNKAI-- 696 Query: 181 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 240 +D + ++ VL Y+ AL+ L ++ + + V G++ +L + Sbjct: 697 ---VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 Query: 241 EDAADVYRGLQERNPE--NWAYYKGLEKALKPANM 273 A + + +P+ N + ++K P + Sbjct: 754 HLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDE 788 Score = 32.4 bits (72), Expect = 0.87, Method: Composition-based stats. Identities = 31/148 (20%), Positives = 61/148 (41%), Gaps = 20/148 (13%) Query: 53 GLTLNCLGKKEEAYELVRRGLRNDLKSHVC-WHVYGLLQRSDKKYDEAIKCYRNALKWDK 111 G+ + L K E+A + + + + D K+ +C +H +L ++K Y++AL+ + Sbjct: 676 GVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEK--------YKSALQELE 727 Query: 112 DNLQILRDLSLLQIQMRD-LEGYRETRYQL------LQLRPAQRASWIGYAIAYHLLEDY 164 + QI+ SL+ + + +T L + L P + I AI L D Sbjct: 728 ELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDD 787 Query: 165 E----MAAKILEEFRKTQQTSPDKVDYE 188 E +I+ + + D D + Sbjct: 788 EEPITQEEQIMGTDESQESSMTDADDTQ 815 >5LVV-A nrPDB Length = 749 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 32/183 (17%), Positives = 66/183 (36%), Gaps = 9/183 (4%) Query: 43 AEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKC 102 H ++L G EEA L R+ L + + + K EA+ Sbjct: 27 GTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH 86 Query: 103 YRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLE 162 Y+ A++ ++ +M+D++G + + +Q+ PA + A + Sbjct: 87 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSG 146 Query: 163 DYEMAAKILEEFRKTQQTSPDKVDY--EYSELLLYQNQVLREAGLYREALEHLCTYEKQI 220 + A + +R + PD D + L Q++ + Y E ++ L + Sbjct: 147 NIPEA---IASYRTALKLKPDFPDAYCNLAHCL----QIVCDWTDYDERMKKLVSIVADQ 199 Query: 221 CDK 223 +K Sbjct: 200 LEK 202 Score = 35.5 bits (80), Expect = 0.093, Method: Composition-based stats. Identities = 26/169 (15%), Positives = 57/169 (33%), Gaps = 18/169 (10%) Query: 117 LRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRK 176 L +L+ ++ + ++E + L++ P A+ A + A L +++ Sbjct: 33 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA---LMHYKE 89 Query: 177 TQQTSPDKVDYEYSELLLYQNQVLREAGLYREALE---HLCTYEKQICDKLAVEETKGEL 233 + SP +++ L+E + AL+ D + + Sbjct: 90 AIRISP-----TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNL---ASI 141 Query: 234 LLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKP----ANMLERLK 278 + +A YR + P+ Y L L+ + ER+K Sbjct: 142 HKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMK 190 Score = 35.1 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 23/147 (15%), Positives = 49/147 (33%), Gaps = 14/147 (9%) Query: 9 KENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYEL 68 +E + +R Y R L+ F E + L GK +EA Sbjct: 41 REQGNIEEAVRLY-----RKALEV---------FPEFAAAHSNLASVLQQQGKLQEALMH 86 Query: 69 VRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMR 128 + +R + G + + A++CY A++ + +L+ + Sbjct: 87 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSG 146 Query: 129 DLEGYRETRYQLLQLRPAQRASWIGYA 155 ++ + L+L+P ++ A Sbjct: 147 NIPEAIASYRTALKLKPDFPDAYCNLA 173 Score = 29.0 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 49/132 (37%), Gaps = 6/132 (4%) Query: 231 GELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKI-YEEAWTKYPR 289 + + +E+A +YR E PE A + L L+ L+ + Y+EA P Sbjct: 37 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 96 Query: 290 -GLVPRRLPLNFLSGEKFKECLDKFLR-MNFSKGCPPVFNTLRSLYKDKEKVAIIEELVV 347 + + + L + R + + + L S++KD I E + Sbjct: 97 FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGN---IPEAIA 153 Query: 348 GYETSLKSCRLF 359 Y T+LK F Sbjct: 154 SYRTALKLKPDF 165 >5OJF-A nrPDB Length = 314 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 46/244 (18%), Positives = 78/244 (31%), Gaps = 37/244 (15%) Query: 84 HVYGLLQRSDKKYDEAIKCYRNALK-WDKDNLQILRDLSLL----------QIQMRDLE- 131 H + S +Y+ A+ + AL+ +K + D++ + Q + +D Sbjct: 32 HNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAH 91 Query: 132 ----GYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAA----KILEEFRKTQQT-SP 182 L + PA A+ A+ Y Y+ A + LE K P Sbjct: 92 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP 151 Query: 183 DKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQIC--DKLAVEETK---GELLLQL 237 D + LL QNQ +A D V +TK L+ Sbjct: 152 DVAKQLSNLALLCQNQ--GKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQ 209 Query: 238 CRLEDAADVYRGLQER---------NPENWAYYKGLEKALKPANMLERLKIYEEAWTKYP 288 + +DA +Y+ + R N EN + E+ + + Y E + Y Sbjct: 210 GKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYK 269 Query: 289 RGLV 292 V Sbjct: 270 ACKV 273 >5WQL-B nrPDB Length = 278 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 47/257 (18%), Positives = 97/257 (37%), Gaps = 24/257 (9%) Query: 30 LKFCKQILSNP--KFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYG 87 L +QIL++ E + L +G+ + LG + A + L ++ G Sbjct: 28 LARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLG 87 Query: 88 LLQRSDKKYDEAIKCYRNALKWDK--DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRP 145 + +D A + + + L+ D + + R ++L + ++ Q P Sbjct: 88 IYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYG--GRDKLAQDDLLAFYQDDP 145 Query: 146 A--QRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREA 203 R+ W +A L++ + + + F K+ DK + ++ + Y + E Sbjct: 146 NDPFRSLW--LYLAEQKLDEKQAKEVLKQHFEKS-----DKEQWGWNIVEFYLGNI-SEQ 197 Query: 204 GLYREALEHLCTYEKQICDKLAVEETK---GELLLQLCRLEDAADVYRGLQERNPENW-- 258 L L+ T + + L+ ET G+ L L L+ A +++ N N+ Sbjct: 198 TLMER-LKADATDNTSLAEHLS--ETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVE 254 Query: 259 AYYKGLEKALKPANMLE 275 Y LE +L + + Sbjct: 255 HRYALLELSLLGQDQDD 271 >6AHD-N nrPDB Length = 941 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 63/411 (15%), Positives = 137/411 (33%), Gaps = 77/411 (18%) Query: 387 IGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINS 446 + +P A ++ A+E PT +EL+L A++ + + A + +++A+ DR I Sbjct: 413 LEEPEDARIMLSRAVECCPTSVELWLALARLETY----ENARKVLNKARENIPTDRHIWI 468 Query: 447 KCAKYMLKANLIKEAEEMCSK-FTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEAL 505 AK + E++ + T + VE +N Q W + A+ Sbjct: 469 TAAKLEEANGNTQMVEKIIDRAITSLRANGVE-INREQ--W--IQDAEECDRAGSVATCQ 523 Query: 506 KKCHEIERHFIEITDDQFDFHTY--------------CMRKITLRSY-VDLLKLEDVLRQ 550 + IE D + HT+ C R + +Y + + + + Sbjct: 524 AVMRAVIGIGIEEEDRK---HTWMEDADSCVAHNALECAR--AIYAYALQVFPSKKSVWL 578 Query: 551 HPFYFK---AARIAIEIYLKLH----------------------DNPLTDENKEHEADTA 585 YF+ R ++E L+ D P A Sbjct: 579 RAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQ-A 637 Query: 586 NMSDKEL--------KKLRNKQRRAQKKAQIEEEKKNAEK-------EKQQRNQKKKKDD 630 N + +E+ + +R + A+ A E Q N + +D Sbjct: 638 NPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDL 697 Query: 631 DDEEIGGPKEEL----IPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKE 686 +E + ++ + ++ + + +E+A + + L + + Sbjct: 698 CEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIG 757 Query: 687 KFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCESKDLSDTVRTVLKQE 737 + ++++ + +P L +RL A K++++T+ QE Sbjct: 758 QLTRARAILEKSRLKNPKNPGLWLESVRLEYRA--GLKNIANTLMAKALQE 806 Score = 38.2 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 61/163 (37%), Gaps = 10/163 (6%) Query: 128 RDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDY 187 D+ R Q P W+ ++YE A ++L + R + +V Sbjct: 622 GDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSA--PTARVFM 679 Query: 188 EYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVY 247 + +L Q+ + L EAL H + K + KG++ Q +E A + Y Sbjct: 680 KSVKLEWVQDNIRAAQDLCEEALRHYEDFPK-------LWMMKGQIEEQKEMMEKAREAY 732 Query: 248 RGLQERNPENWAYYKGLEKALKPANMLERL-KIYEEAWTKYPR 289 ++ P + + L + + L R I E++ K P+ Sbjct: 733 NQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPK 775 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 53/166 (31%), Gaps = 21/166 (12%) Query: 378 YYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQAL 437 Y+ H G + A+ P L+L+ AK AG++ A + A Sbjct: 582 YFEKNH----GTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQA 637 Query: 438 DTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKA 497 + I K + + + A + +K +A + ++ W Sbjct: 638 NPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWV---------- 687 Query: 498 MNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLK 543 + A C E RH+ DF M K + ++++ Sbjct: 688 QDNIRAAQDLCEEALRHYE-------DFPKLWMMKGQIEEQKEMME 726 >5DSE-A nrPDB Length = 837 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 36/74 (48%) Query: 43 AEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKC 102 H +++ L L+ LG+ A +++R ++ + +H W+ G + ++ A +C Sbjct: 755 PTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATEC 814 Query: 103 YRNALKWDKDNLQI 116 + AL+ + + + Sbjct: 815 FLTALELEASSPAV 828 Score = 39.4 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 49/151 (32%), Gaps = 7/151 (4%) Query: 38 SNPKFAEHGETLAMKGLTLNC------LGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQR 91 S PK + + + L+ +GK EA + SH ++ G + Sbjct: 676 SAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAE 735 Query: 92 SDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASW 151 DEA + Y AL +++ ++ L+L+ Q+ + +Q+ W Sbjct: 736 LRGSMDEARRWYEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVW 795 Query: 152 IGYAIAYHLLEDYEMAAK-ILEEFRKTQQTS 181 G + A + L + Sbjct: 796 NGLGEVLQAQGNDAAATECFLTALELEASSP 826 >2GW1-A nrPDB Length = 514 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 93/505 (18%), Positives = 185/505 (36%), Gaps = 40/505 (7%) Query: 93 DKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWI 152 +KKYD+AIK Y AL+ K++ +LS + + DL+ E + L+L+P + Sbjct: 19 NKKYDDAIKYYNWALEL-KEDPVFYSNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLL 77 Query: 153 GYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEH 212 A A L + A L + + E + E L ++A+ Sbjct: 78 RRASANEGLGKFADAMFDLSVL--SLNGDFNDASIEP----------MLERNLNKQAMSK 125 Query: 213 LCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPE--NWAYYKGLEK-ALK 269 L +K +T +L A + QE P + A + G+ K L Sbjct: 126 LK-------EKFGDIDTATATPTELS--TQPAKERKDKQENLPSVTSMASFFGIFKPELT 176 Query: 270 PANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTL 329 AN E + +E + +R P ++ ++ + K N Sbjct: 177 FANYDESNEADKELMNGL--SNLYKRSPESYDKADESFTKAARLFEEQLDK------NNE 228 Query: 330 RSLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQ 389 K+K +++ + + LK+ L D K + Y+A Sbjct: 229 DEKLKEKLAISLEHTGIFKF---LKNDPLGAHEDIKKAIELFPRVNSYIYMALIMADRND 285 Query: 390 PSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCA 449 + Y + A++ ++ + ++ N +A + D+A+ LD + F + A Sbjct: 286 STEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLA 345 Query: 450 KYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCH 509 + N + E + S+ R+ A E N + T+ KA+ ++ A++ + Sbjct: 346 CLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEI--LTDKNDFDKALKQYDLAIELEN 403 Query: 510 EIERHFIEITDDQFDFHTYCMRKITLRSYVDLLK-LEDVLRQHPFYFKAARIAIEIYLKL 568 +++ ++ I T R T+ ++++ LE + P +A ++ L+ Sbjct: 404 KLDGIYVGIAP-LVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQ 462 Query: 569 HDNPLTDENKEHEADTANMSDKELK 593 D E AD A +++L+ Sbjct: 463 EDIDEAITLFEESADLARTMEEKLQ 487 Score = 30.9 bits (68), Expect = 2.7, Method: Composition-based stats. Identities = 50/314 (15%), Positives = 122/314 (38%), Gaps = 19/314 (6%) Query: 11 NALFKRILRCYE--HKQYRNGLKFCK-QILSNPKFAEHGETLAMK----GLTLNCLGKKE 63 + L+KR Y+ + + + + Q+ N + + E LA+ G+ Sbjct: 195 SNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPL 254 Query: 64 EAYELVRRGLRN--DLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLS 121 A+E +++ + + S++ L+ E + ALK D +N + Sbjct: 255 GAHEDIKKAIELFPRVNSYI---YMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRG 311 Query: 122 LLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTS 181 + +++ + + + +L P +I A + ++ + E ++ + Sbjct: 312 QMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEA 371 Query: 182 PDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLE 241 P+ ++ ++E+L +N + Y A+E L I +A K LL + +E Sbjct: 372 PEVPNF-FAEILTDKNDFDKALKQYDLAIE-LENKLDGIYVGIAPLVGKATLLTRNPTVE 429 Query: 242 ---DAADVYRGLQERNPENWAYYKGL-EKALKPANMLERLKIYEEAWTKYPRGLVPRRLP 297 +A ++ + +P + GL + L+ ++ E + ++EE+ R + + Sbjct: 430 NFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESAD-LARTMEEKLQA 488 Query: 298 LNFLSGEKFKECLD 311 + F K ++ + Sbjct: 489 ITFAEAAKVQQRIR 502 >4JA9-A nrPDB Length = 488 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 41/221 (18%), Positives = 76/221 (34%), Gaps = 36/221 (16%) Query: 546 DVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKK 605 D +Y +A A + L L D + +DK+ K + Sbjct: 81 DKKYIKGYYRRA---ASNMALGKFRAALRDYETVVK---VKPNDKDAKMKYQECS----- 129 Query: 606 AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAK---VETPLEEAIKFLT 662 +I ++K +++ D D E ++E KL T +++ +++ Sbjct: 130 -KIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYK 188 Query: 663 PLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCE 722 K L + A++I + ++ L L ++ + + VC Sbjct: 189 DQKKLHRK------CAYQILVQVKEVLCKLSTL------------VETTLKETEKITVCG 230 Query: 723 SKDLSDTVRTVLKQ-EMNRLFGATNPKNFNETFLKRNSDSL 762 D +L E+N L TNP FN F+ R S S+ Sbjct: 231 --DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSV 269 Score = 37.8 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 69/197 (35%), Gaps = 32/197 (16%) Query: 94 KKYDEAIKCYRNALKWDKDNLQIL--RDLSLLQIQ-----MRDLEGYRETRYQLLQLRPA 146 K Y+ AIK Y A++ + N R L+ L+ + + D E + ++ Sbjct: 31 KDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYR 90 Query: 147 QRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKV-DYEYSELLLYQNQVLREAGL 205 + AS + L DYE K+ DK +Y E + + Sbjct: 91 RAASNMALGKFRAALRDYETVVKV---------KPNDKDAKMKYQEC-----SKIVKQKA 136 Query: 206 YREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLE 265 + A+ + + + D L +E E +LED +++ +YK + Sbjct: 137 FERAIAG-DEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDL----MQWYKDQK 191 Query: 266 K-----ALKPANMLERL 277 K A + ++ + Sbjct: 192 KLHRKCAYQILVQVKEV 208 >5OJ8-A nrPDB Length = 255 Score = 39.4 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 43/196 (21%), Positives = 71/196 (36%), Gaps = 28/196 (14%) Query: 84 HVYGLLQRSDKKYDEAIKCYRNALK-WDKDNLQILRDLSLL----------QIQMRDLEG 132 H + S +Y+ A+ + AL+ +K + D++ + Q + +D Sbjct: 54 HNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAN 113 Query: 133 YRET-----RYQLLQLRPAQRASWIGYAIAYHLLEDYEMAA----KILEEFRKTQ-QTSP 182 L + PA A+ A+ Y Y+ A + LE K + P Sbjct: 114 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHP 173 Query: 183 DKVDYEYSELLLYQNQVLREAGL--YREALEHLCTYEKQICDKLAVEETK---GELLLQL 237 D + LL QNQ E Y+ ALE T K D V +TK L+ Sbjct: 174 DVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT--KLGPDDPNVAKTKNNLASCYLKQ 231 Query: 238 CRLEDAADVYRGLQER 253 + + A +Y+ + R Sbjct: 232 GKFKQAETLYKEILTR 247 >6B85-J nrPDB Length = 223 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 42/104 (40%), Gaps = 12/104 (11%) Query: 340 AIIEEL--VVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYI 397 +++E+L + + K PND W + L + +K+G+ A E Sbjct: 123 SVLEKLKRLDEAAEAYKKAIELKPNDASA--------WKE--LGKVLEKLGRLDEAAEAY 172 Query: 398 NTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTAD 441 AIE P E + K+ + G + EAA +A LD D Sbjct: 173 KKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 42/93 (45%) Query: 53 GLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKD 112 G L L + +EA E ++ + W G + + DEA + Y+ A++ D + Sbjct: 122 GSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPE 181 Query: 113 NLQILRDLSLLQIQMRDLEGYRETRYQLLQLRP 145 + + ++L + ++ L+ E + ++L P Sbjct: 182 DAEAWKELGKVLEKLGRLDEAAEAYKKAIELDP 214 Score = 37.4 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 9/183 (4%) Query: 99 AIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYA--I 156 AI Y+ D + L + LL I + + Q Q+ + R A + Sbjct: 27 AIIWYQITTNPDTSQIATLLSMQLLLIALMLVVIALLLSRQTEQVAESIRRDVSALAYVM 86 Query: 157 AYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALE-HLCT 215 LL + E ++K + P+ + L VL + EA E + Sbjct: 87 LGLLLSLLNRLSLAAEAYKKAIELDPN-----DALAWLLLGSVLEKLKRLDEAAEAYKKA 141 Query: 216 YEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLE 275 E + D A +E G++L +L RL++AA+ Y+ E +PE+ +K L K L+ L+ Sbjct: 142 IELKPNDASAWKEL-GKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLD 200 Query: 276 RLK 278 Sbjct: 201 EAA 203 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 32/63 (50%) Query: 53 GLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKD 112 G L LG+ +EA E ++ + D + W G + + DEA + Y+ A++ D + Sbjct: 156 GKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPN 215 Query: 113 NLQ 115 +L+ Sbjct: 216 DLE 218 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 77/195 (39%), Gaps = 43/195 (22%) Query: 67 ELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQ 126 E V +R D+ S + + + GLL + A + Y+ A++ D ++ L + + Sbjct: 69 EQVAESIRRDV-SALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEK 127 Query: 127 MRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVD 186 ++ L+ E + ++L+P ++W L + AA E ++K + P+ Sbjct: 128 LKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAA---EAYKKAIELDPEDA- 183 Query: 187 YEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADV 246 EA + L G++L +L RL++AA+ Sbjct: 184 ---------------------EAWKEL-----------------GKVLEKLGRLDEAAEA 205 Query: 247 YRGLQERNPENWAYY 261 Y+ E +P + ++ Sbjct: 206 YKKAIELDPNDLEHH 220 Score = 32.8 bits (73), Expect = 0.59, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 43/125 (34%), Gaps = 16/125 (12%) Query: 393 ALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYM 452 A E AIE P +L+ + + + EAA +A L D + K + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 453 LKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIE 512 K + EA E K + E A+A+K + K E L + E Sbjct: 160 EKLGRLDEAAEAYKK----------------AIELDPEDAEAWKELGKVLEKLGRLDEAA 203 Query: 513 RHFIE 517 + + Sbjct: 204 EAYKK 208 >5MGX-E nrPDB Length = 290 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 1/86 (1%) Query: 380 LAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDT 439 LA K+ AL + +E P I+ K K+ G EA + A L+ Sbjct: 188 LAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEP 247 Query: 440 ADRFINSKCAKYMLKANLIKEAEEMC 465 +++ I+++ +K ++K + + + E Sbjct: 248 SNKTIHAELSK-LVKKHAAQRSTETA 272 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 36/128 (28%), Positives = 47/128 (36%), Gaps = 18/128 (14%) Query: 32 FCKQILSNPK----FAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHV-- 85 K I S+ K F E + L +K LN L + + R LR S V H Sbjct: 157 AIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALR--SCSLVLEHQPD 214 Query: 86 -YGLLQRSDK------KYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRY 138 L R K +Y EAI R ALK + N I +LS L ++ R T Sbjct: 215 NIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL---VKKHAAQRSTET 271 Query: 139 QLLQLRPA 146 L + Sbjct: 272 ALYRKMLG 279 >2Y4T-A nrPDB Length = 450 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 68/202 (33%), Gaps = 18/202 (8%) Query: 98 EAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIA 157 +AI + A K DN + +S L Q+ D E + L+L + + Y Sbjct: 195 KAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQV 254 Query: 158 YHLLEDYEMAAKIL---------EEFRKTQQTSPDKVDY----EYSELLLYQNQVLREAG 204 L + E A +++ ++ +T P +Y + + + Sbjct: 255 KKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKD--EKPV 312 Query: 205 LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGL 264 + E D + + + E L ++A Y QE N + +GL Sbjct: 313 EAIRVCSEVLQMEP---DNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGL 369 Query: 265 EKALKPANMLERLKIYEEAWTK 286 EKA + ++ Y+ K Sbjct: 370 EKAQRLLKQSQKRDYYKILGVK 391 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 49/307 (15%), Positives = 97/307 (31%), Gaps = 38/307 (12%) Query: 166 MAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLA 225 A L +F PD Y V G + AL L + D A Sbjct: 41 QLADALSQFHAAVDGDPDNYIAYYRRA-----TVFLAMGKSKAALPDLTKVIQLKMDFTA 95 Query: 226 VEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWT 285 +G LLL+ +L++A D ++ + + NP E + E ++ +A Sbjct: 96 ARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEK---EAQSQLIKSDEMQRLRSQALN 152 Query: 286 KYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEEL 345 + G FL LR L + + I E Sbjct: 153 AFGSGD---------------YTAAIAFLDKILEVCVWD--AELREL---RAECFIKEGE 192 Query: 346 VVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTP 405 + LK+ +D E Y ++ Y ++G ++L + ++ Sbjct: 193 PRKAISDLKAASKLK--NDNTE--------AFYKISTLYYQLGDHELSLSEVRECLKLDQ 242 Query: 406 TLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMC 465 F ++ K I+ A + + + D ++ + + + ++ E +C Sbjct: 243 DHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERIC 302 Query: 466 SKFTREG 472 F+++ Sbjct: 303 HCFSKDE 309 >3NF1-A nrPDB Length = 311 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 43/196 (21%), Positives = 71/196 (36%), Gaps = 28/196 (14%) Query: 84 HVYGLLQRSDKKYDEAIKCYRNALK-WDKDNLQILRDLSLL----------QIQMRDLEG 132 H + S +Y+ A+ + AL+ +K + D++ + Q + +D Sbjct: 31 HNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAN 90 Query: 133 YRET-----RYQLLQLRPAQRASWIGYAIAYHLLEDYEMAA----KILEEFRKTQ-QTSP 182 L + PA A+ A+ Y Y+ A + LE K + P Sbjct: 91 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHP 150 Query: 183 DKVDYEYSELLLYQNQVLREAGL--YREALEHLCTYEKQICDKLAVEETK---GELLLQL 237 D + LL QNQ E Y+ ALE T K D V +TK L+ Sbjct: 151 DVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQT--KLGPDDPNVAKTKNNLASCYLKQ 208 Query: 238 CRLEDAADVYRGLQER 253 + + A +Y+ + R Sbjct: 209 GKFKQAETLYKEILTR 224 >6ICZ-I nrPDB Length = 855 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 43/344 (12%), Positives = 116/344 (33%), Gaps = 44/344 (12%) Query: 325 VFNTLRSLYKDKEKVAIIE-ELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQY----- 378 F + +++Y + I ++V+ Y L+ + F + E + W Sbjct: 499 TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWS 558 Query: 379 -YLAQHYDKIG--QPSIALEYINTAIESTPTLI--ELFLVKAKIYKHAGNIKEAARWMDE 433 YL + + G + A + A++ P L+L+ A++ + G + A + Sbjct: 559 TYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYER 618 Query: 434 A-QALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVEN---------LNEMQ 483 A +A++ A ++ Y+ +A I + + + + +M+ Sbjct: 619 ATRAVEPAQQYDMFNI--YIKRAAEIYGVTHTRGIYQKA-IEVLSDEHAREMCLRFADME 675 Query: 484 CMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLK 543 C + + A+A F + + D + +R Sbjct: 676 CKLGEIDRARAIY---SFCSQICDPRTTGAFWQTWKD-------FEVRHGN--------- 716 Query: 544 LEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQ 603 ED +++ ++ + + + + + ++++ + K + Sbjct: 717 -EDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQR 775 Query: 604 KKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKL 647 + E +++ Q + + D EE+ +++ PE++ Sbjct: 776 AEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEI 819 >3ZFW-A nrPDB Length = 263 Score = 37.4 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 36/180 (20%), Positives = 55/180 (30%), Gaps = 21/180 (11%) Query: 132 GYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAA----KILEEFRKTQQT-SPDKVD 186 L + PA A+ A+ Y Y+ A + LE K PD Sbjct: 49 ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAK 108 Query: 187 YEYSELLLYQNQVLREAGLYREALEHLCTYEKQIC--DKLAVEETK---GELLLQLCRLE 241 + LL QNQ +A D V +TK L+ + + Sbjct: 109 QLSNLALLCQNQ--GKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQ 166 Query: 242 DAADVYRGLQER---------NPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLV 292 DA +Y+ + R N EN + E+ + + Y E + Y V Sbjct: 167 DAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKV 226 >5ZVW-A nrPDB Length = 378 Score = 37.1 bits (84), Expect = 0.038, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 23/175 (13%) Query: 64 EAYELVRRGLRNDLKSHVCWHVYGLLQRSD--KKYDEAIKCYRNALKWDKDN-LQILRD- 119 EA + R + N + +C+ Y + + + YDEA K Y K+ K+ Q + D Sbjct: 205 EARQHSNRAIENSNVNRICFFAYLTIGNTLIFEDYDEAKKAYIKGQKYAKNPVHQEMLDG 264 Query: 120 ----LSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFR 175 LS + + Y + LQLR A Y + E A +IL+E Sbjct: 265 ALCFLSNIWKKENQWVNYNSDNIKYLQLR----------AFYYINQGNIEEATEILDEL- 313 Query: 176 KTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETK 230 +S D+ + E Y+ + ++ Y +++ + + + +L + + + Sbjct: 314 ----SSRDQDENELGFYYYYKGLISQDKTDYAKSIRYFKKSDDKYFIQLPLLQLE 364 >6FUZ-A nrPDB Length = 337 Score = 36.7 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 36/196 (18%), Positives = 66/196 (33%), Gaps = 28/196 (14%) Query: 84 HVYGLLQRSDKKYDEAIKCYRNALK-WDKDNLQILRDLSLL----------QIQMRDLEG 132 H + S +Y+ A+ + AL+ +K + D++ + Q + +D Sbjct: 17 HNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAN 76 Query: 133 YRETRYQLLQ-----LRPAQRASWIGYAIAYHLLEDYEMAA----KILEEFRKTQ-QTSP 182 + + PA A+ A+ Y Y+ A + LE K + P Sbjct: 77 LLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHP 136 Query: 183 DKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQIC--DKLAVEETK---GELLLQL 237 D + LL QNQ E + + D V +TK L+ Sbjct: 137 DVAKQLNNLALLCQNQGKYEE--VEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQ 194 Query: 238 CRLEDAADVYRGLQER 253 + + A +Y+ + R Sbjct: 195 GKFKQAETLYKEILTR 210 >5UDI-A nrPDB Length = 479 Score = 36.3 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 74/356 (20%), Positives = 121/356 (33%), Gaps = 62/356 (17%) Query: 111 KDNLQILR-----DLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYE 165 KD+L+ LR +LS+ +M DLE + + L + + A HL E Sbjct: 12 KDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIH-NLLAYVKHLKGQNE 70 Query: 166 MAAKILEEFRKTQQTSPDKVDYEYSEL----LLYQNQVLREAGLYREALEHLCTYEKQI- 220 A K L+E Q D S + + + + L+ + K++ Sbjct: 71 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 130 Query: 221 --------CDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGL-EKALKPA 271 C ++ EE L E A + + E +PEN G A + Sbjct: 131 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 190 Query: 272 NMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRS 331 + TK + LPL + +R+N G V L+ Sbjct: 191 GF--------KLATKNHK--PFSLLPL------------RQAVRLNPDNGYIKVLLALK- 227 Query: 332 LYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPS 391 +D+ + A E+ + ++ S +V Y A+ Y + G Sbjct: 228 -LQDEGQEAEGEKYIEEALANMSSQT-----------------YVFRYAAKFYRRKGSVD 269 Query: 392 IALEYINTAIESTPTLIELFLVKAKIYKHAG-NIKEAARWMDEAQALDTADRFINS 446 ALE + A++ TPT + L YK IKEA + Q + D+ I S Sbjct: 270 KALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRS 325 >5FZQ-A nrPDB Length = 131 Score = 36.3 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 42/106 (39%) Query: 97 DEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAI 156 +EAIK R A+ D +N++ L +L+ L Q E + + + L P + A+ Sbjct: 22 EEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAV 81 Query: 157 AYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLRE 202 E A K + + + + +++++R+ Sbjct: 82 LLAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAAARRKSRLMRK 127 Score = 33.2 bits (74), Expect = 0.50, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 36/80 (45%) Query: 388 GQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSK 447 G+ A++Y+ A+ P I+ A + G +EA ++M +A +LD + S Sbjct: 19 GKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSN 78 Query: 448 CAKYMLKANLIKEAEEMCSK 467 A + + +EA + K Sbjct: 79 LAVLLAQEGKAEEAIKYMRK 98 >6FRK-r nrPDB Length = 605 Score = 35.9 bits (81), Expect = 0.072, Method: Composition-based stats. Identities = 27/198 (13%), Positives = 66/198 (33%), Gaps = 14/198 (7%) Query: 16 RILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLN-CLGKKEEAYELVRRGLR 74 + + KQ+ ++ ++ + + E+ + + L G +A ++R Sbjct: 344 QAAQLCREKQHTKAIELLQEF--SDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEE 401 Query: 75 NDLKSHVCWHVYGLLQRSD------KKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMR 128 K + + + + + + +AI+ Y+N +L ++R+ + +++ Sbjct: 402 LKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSSAHLSLIREAANFKLKYG 461 Query: 129 DLEGYRETRYQLLQLRPAQRASWIGYAIAYHL-LEDYEMAAKILEEFRKTQQTSPDKVDY 187 + QL + P + AY L + A + D Sbjct: 462 RKKEAISDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEAL 521 Query: 188 EYSELLLYQNQVLREAGL 205 E S Y +R+ G Sbjct: 522 ENSPGATY----IRKKGG 535 >1IHG-A nrPDB Length = 370 Score = 35.5 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 54/146 (36%), Gaps = 6/146 (4%) Query: 328 TLRSLYKDKEKVAIIEELVVGYETSLK---SCRLFNPNDDGKEEPPTTLLWVQYYLAQHY 384 L+++ K E + Y L+ R + DG + P L V + Sbjct: 225 DLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCV-LNIGACK 283 Query: 385 DKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFI 444 K+ A++ A+E P+ + +A+ ++ +A + +AQ + D+ I Sbjct: 284 LKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAI 343 Query: 445 NSKC--AKYMLKANLIKEAEEMCSKF 468 ++ K +KA KE F Sbjct: 344 QAELLKVKQKIKAQKDKEKAAYAKMF 369 >5G04-X nrPDB Length = 599 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 1/86 (1%) Query: 41 KFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAI 100 + ++ + + K L+ K E+ L+R L N V + G + +Y EA+ Sbjct: 471 QRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDC-VLHRILGDFLVAVNEYQEAM 529 Query: 101 KCYRNALKWDKDNLQILRDLSLLQIQ 126 Y AL D ++ + L + ++ + Sbjct: 530 DQYSIALSLDPNDQKSLEGMQKMEKE 555 >5YFP-B nrPDB Length = 971 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 45/246 (18%), Positives = 81/246 (32%), Gaps = 37/246 (15%) Query: 165 EMAAKILEEFRKTQQTSPDKVD--YEYSELLLYQNQVLREAGLYREALEHLCTYEKQICD 222 E + IL++F+ Q S DK Y E L Y L + L+HL ++ Sbjct: 46 ETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPL-NGQEMSKELQHLPNDSMRLNY 104 Query: 223 KLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEE 282 + ++ + L+ +D+ + +R + K L N + +KI + Sbjct: 105 LVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVKIKNK 164 Query: 283 AWTKYP----------RGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCP--------- 323 Y + P+ N ++ E + +D+ +R K P Sbjct: 165 LDQIYKEFDEKTNEKNQCDSPKE---NQINVESLNKKVDEVIRTTTFKLKPLMDNYQKIL 221 Query: 324 -----PVFNTLRSLY----KDKEKVAI---IEELVVGYETSLKSCRLFNPNDDGKEEPPT 371 F L Y K ++ E ++ Y L R FN + D + Sbjct: 222 NYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDASQSLVI 281 Query: 372 TLLWVQ 377 +W Q Sbjct: 282 KRIWTQ 287 >5JJT-A nrPDB Length = 479 Score = 34.4 bits (77), Expect = 0.24, Method: Composition-based stats. Identities = 39/223 (17%), Positives = 70/223 (31%), Gaps = 39/223 (17%) Query: 546 DVLRQHPFYFKAARIAIEIYLKL--HDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQ 603 D +Y + A YL + + L D + + +D + + + +A Sbjct: 73 DSRYSKGYYRRGAA-----YLAMGKFKDALKDFQQVKR---LSPNDPDATRKLKECEKAV 124 Query: 604 KKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTP 663 K + EE E+ + + D + + ++ E L+ + Sbjct: 125 MKLKFEEAISVPVSER-----RSVAESIDFHTIEVEPQYSGARIEGEEVTLDFVKTMMED 179 Query: 664 LKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSH----PWLHECMIRLFNTA 719 KN +A++I + + LL L S+ H +H L N Sbjct: 180 FKNQKTLHKR---YAYQIVLQTRQILLALPSLVDISVPHGKHITVCGDVHGQFYDLLNIF 236 Query: 720 VCESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSL 762 E+N L NP FN F+ R S S+ Sbjct: 237 -----------------ELNGLPSEENPYLFNGDFVDRGSFSV 262 >3GDB-A nrPDB Length = 937 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 36/112 (32%), Gaps = 4/112 (3%) Query: 572 PLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDD 631 K TA+ + A+ + + E+K +E + + + K D Sbjct: 58 RENKLEKAEGVATASETASPASNEAATTETAEAASAAKPEEKASEVVAETPSAEAKPKSD 117 Query: 632 DEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYF 683 E P+ ++ P EA K ++ V E L EI F Sbjct: 118 KETEAKPEATNQGDE----SKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKF 165 >5XJC-J nrPDB Length = 848 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 35/223 (15%), Positives = 82/223 (36%), Gaps = 22/223 (9%) Query: 86 YGLLQRSDKKYDEAIKCYRNALK--WDKDNLQILRDLSLLQIQMRDLEGYRE-----TRY 138 + + + K+++ Y+ AL +D ++ ++ ++ + + D G + R+ Sbjct: 419 FAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRF 478 Query: 139 QLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQ-- 196 Q + A ++ + L+E A + E + + P + + + +Y Sbjct: 479 QYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWI 538 Query: 197 NQVLRE----------AGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADV 246 N L E +Y+ +LE L ++K K+ + + ++ L A Sbjct: 539 NYALYEELEAKDPERTRQVYQASLE-LIPHKKFTFAKMWIL--YAQFEIRQKNLSLARRA 595 Query: 247 YRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPR 289 + P+N + +E L+ K+YE+ P Sbjct: 596 LGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPE 638 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 12/172 (6%) Query: 151 WIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREA--GLYRE 208 WI YA+ L + + + + ++ + + P K +LY +R+ L R Sbjct: 537 WINYALYEEL--EAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARR 594 Query: 209 ALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKAL 268 AL + K +KL + EL LQL + +Y E PEN + + Sbjct: 595 ALG--TSIGKCPKNKL--FKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELE 650 Query: 269 KPANMLERLKIYEEAWTKYPRGLVPRRLPLNF----LSGEKFKECLDKFLRM 316 ++R + E PR +P L ++ + E+ + + + R+ Sbjct: 651 TILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRL 702 >3JCM-G nrPDB Length = 899 Score = 32.4 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 72/395 (18%), Positives = 127/395 (32%), Gaps = 69/395 (17%) Query: 138 YQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDY-----EYSEL 192 +L+Q P W +A E Y ++L F++ + + D E S Sbjct: 503 KKLIQWDPCDTVLWSRLKMA---TESYHKIEELLAFFQELLFQTKNSDDIRANMREKSPG 559 Query: 193 LLYQNQVLR---EAGLYREAL---EHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADV 246 LL + G R+ L + + + D + K +LL + +L++ D Sbjct: 560 LLMMYVSEYWKAQKGDTRQTLVLIDQIIDFAPHNLD---LRFFKIKLLGRSLQLDELRDF 616 Query: 247 YRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKF 306 ++ + + LE KI Y +NFL + Sbjct: 617 FQ--------------------QTFSSLEDFKISGTERLYYKY--------VNFLRYQDL 648 Query: 307 KECLDKFLRMNFSKGCP---PVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPND 363 E KFL K P F L +Y + + E T L RL Sbjct: 649 NEEAIKFLNERCLKSFPICHKFFLQLGQIYHSMGNIEMSRE------TYLSGTRLV---- 698 Query: 364 DGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGN 423 P LLWV D + P A ++ + P + ++ K ++ GN Sbjct: 699 -----PNCPLLWVSLSKIDEID-LKNPVRARSILDRGLLKNPDDVLFYIAKIQMEIRLGN 752 Query: 424 IKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQ 483 + +A + +A ++ + + K N + + R + L E+ Sbjct: 753 LDQAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQDALRRTQNDHRVLLEIG 812 Query: 484 CMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEI 518 ++ AQ ++ ALKKC R+ Sbjct: 813 VSFY--AEAQYETSLKWLERALKKCS---RYGDTW 842 >1F5N-A nrPDB Length = 592 Score = 32.4 bits (72), Expect = 0.90, Method: Composition-based stats. Identities = 37/240 (15%), Positives = 92/240 (38%), Gaps = 13/240 (5%) Query: 453 LKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIE 512 L + +EA E+ F R V++L + + + + N+ + +C + Sbjct: 356 LHRDSEREAIEV---FIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASS-DRCSGLL 411 Query: 513 RHFIEITDDQFDFHTYCMRKITLRSYVDLLK-LEDVLRQHPFYFKAARIAIEIYLKLHDN 571 + +++ Y + R +V L+ L+ + P A ++ YLK + Sbjct: 412 QVIFSPLEEEVKAGIYS-KPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLK---S 467 Query: 572 PLTDENKEHEAD-TANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDD 630 + + + D T +KE++ R K AQ A++ E + ++ ++ ++ ++ Sbjct: 468 KESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLHEMQRKNEQMMEQKERSYQEH 527 Query: 631 DDEEIGGPKEE---LIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEK 687 + + + L+ E+ + L+E + L ++ + + R+ K Sbjct: 528 LKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587 >5G05-C nrPDB Length = 597 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 45/244 (18%), Positives = 79/244 (32%), Gaps = 56/244 (22%) Query: 84 HVYGLLQRSDKKYDEAIKCYRNA-----LKWDK--------DNLQILRDLSLLQIQMRDL 130 ++YG++ R EAI + A L W + ++L+ LSL M++ Sbjct: 173 YLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEF 232 Query: 131 -EGYRETRYQLLQLRPAQRASW------------IGYAIAYHLLEDYEMAAKILEEFRKT 177 + T QL++ + + A+AYH + D + A I E RK Sbjct: 233 FLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRK- 291 Query: 178 QQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTY--EKQIC-----------DKL 224 Q + + LLY + E L + Y E +K Sbjct: 292 -QDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKA 350 Query: 225 AVEETKG---------------ELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALK 269 A+ + +++ A YR E N ++ + GL + + Sbjct: 351 ALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYE 410 Query: 270 PANM 273 M Sbjct: 411 ILKM 414 >6AF0-A nrPDB Length = 939 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 15/86 (17%) Query: 236 QLCRLEDAADVYRGLQERNPEN------WAYYKGLEKALKPANMLERLKIYEEAWTKYPR 289 QL +DA + E NP++ Y P N E +++Y++A T+Y + Sbjct: 241 QLGFKDDAKIAWERCLEINPDSKHANILLGLYYLDASGHVPTNSPEFIRLYKKAMTEYTQ 300 Query: 290 G--LVPRRLPLN-------FLSGEKF 306 + + LPL FLS ++F Sbjct: 301 KSFKLDKNLPLTCATFAGYFLSRKQF 326 >6F91-A nrPDB Length = 764 Score = 30.5 bits (67), Expect = 3.5, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 66/192 (34%), Gaps = 27/192 (14%) Query: 339 VAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIG--QPSIALEY 396 V+++ +++V R + E TT + Y Y ++G E Sbjct: 399 VSVLADMIVKEVKGFDYERAY-------EAMKTTAMNSNYDCLPEYREMGYVPFDKEAES 451 Query: 397 INTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQA----LDTADRFINSKCAKYM 452 ++ +E + + + A+ K G + +++ A + +D +++ + +K Sbjct: 452 VSKTLEYA---YDDYCI-AQAAKKLGKEDDYHYFLNRALSYQTLIDPETKYMRGRDSKGD 507 Query: 453 LKANLIKEAEEMCSKFTREGTSAVENLNE---MQCMWFQTECAQAYKAMNKFGEALKKCH 509 + A + ++ E MQ W+ + Q Y K+ Sbjct: 508 WRTPFTPVAYQGPG-----SVHGWGDITEGFTMQYTWYVPQDVQGYINEAGKELFRKRLD 562 Query: 510 EIERHFIEITDD 521 E+ E+ DD Sbjct: 563 ELFTV--ELPDD 572 >3ATP-A nrPDB Length = 170 Score = 30.5 bits (67), Expect = 3.5, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 103 YRNALKWDKDNLQILRDLSLLQIQM-RDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLL 161 + NALK DK+N +L+ + Q + +TR L + + Sbjct: 9 FFNALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVA 68 Query: 162 EDYEMAAKILEEFRK 176 E E A+ L++ K Sbjct: 69 ELMESASISLKQAEK 83 >6FAI-j nrPDB Length = 463 Score = 30.5 bits (67), Expect = 3.5, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 48/130 (36%), Gaps = 16/130 (12%) Query: 542 LKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANM-SDKELKKLRNKQR 600 L+ +DV P +A +Y D+ D + + + + + N+Q+ Sbjct: 50 LRKKDVSSTKPKGRRAHVGEAALYGINFDDSEYDYTQHLKPIGLDPENSIFIASKGNEQK 109 Query: 601 RAQKKAQ---IEEEKKNAEKEKQQ-----------RNQKKKKDDDDEEIGGPKEELIPEK 646 +K + IE + + E EK + D +EI G K ++ P Sbjct: 110 VEKKNIEDLFIEPKYRRDEIEKDDALPVFQRGMAKPEYLLHQQDTTDEIRGFKPDMNP-A 168 Query: 647 LAKVETPLEE 656 L +V LE+ Sbjct: 169 LREVLEALED 178 >6GMH-U nrPDB Length = 776 Score = 30.5 bits (67), Expect = 3.6, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 34/110 (30%), Gaps = 9/110 (8%) Query: 532 KITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKE 591 + + +++ D K + + + + + E N D E Sbjct: 243 EGSEKAHSDDEKWGREDKSDQSDDEKIQNS---------DDEERAQGSDEDKLQNSDDDE 293 Query: 592 LKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEE 641 + + + R Q ++ EK + D+DDE+ EE Sbjct: 294 KMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEE 343 >6FES-A nrPDB Length = 367 Score = 30.1 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 19/125 (15%), Positives = 47/125 (37%), Gaps = 7/125 (5%) Query: 168 AKILEEFRKTQQTSPDKVDYEYSELL--LYQNQVLREAGLYREALEHLCTYEKQICDKLA 225 ++E +T SP + E +L L N ++ +A++ + ++ D + Sbjct: 200 VHTMKEITETMGFSPVALVLEAIMMLVKLMLNSEIKITSDLIDAVKKMLDMVTRLLDLMV 259 Query: 226 VEETKGELLLQ-----LCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIY 280 E ++ L L +A +V + E+NPE+ ++ + + + + + Sbjct: 260 DPNLNEEQYIKMVVDALKILIEAVNVLIKMVEKNPEDMEFWNLIYRLVHVMKEVTETMGF 319 Query: 281 EEAWT 285 Sbjct: 320 SSVAK 324 >5LJ5-s nrPDB Length = 175 Score = 29.7 bits (65), Expect = 4.8, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 29/79 (36%), Gaps = 6/79 (7%) Query: 272 NMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMN---FSKGCPPVFNT 328 N + EE KYPR R +P N S +D +L+ P + Sbjct: 80 NDDDDTLFLEEYRRKYPRIDTSRYIP-NESSEVSLLGIVDSYLKHQEIVLDTLLPQTVSN 138 Query: 329 LRSLYKD--KEKVAIIEEL 345 + D ++ I+EE+ Sbjct: 139 QWRINNDYIRQTCTIVEEM 157 >6FO1-G nrPDB Length = 665 Score = 29.7 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 39/112 (34%), Gaps = 3/112 (2%) Query: 71 RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDL 130 G+ D + + G KYDEAI CY + D N + + + +++ Sbjct: 124 DGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF 183 Query: 131 EGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSP 182 + L + ++ A L+ E A K ++ + + P Sbjct: 184 AVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK---DYERVLELEP 232 >4HOQ-A nrPDB Length = 482 Score = 29.4 bits (64), Expect = 6.6, Method: Composition-based stats. Identities = 78/411 (18%), Positives = 131/411 (31%), Gaps = 75/411 (18%) Query: 154 YAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQ--VLREAGLYREALE 211 A HL + A + LE+ + Q E L+ + N V EA + Sbjct: 57 LAYVKHLKGQNKDALECLEQAEEIIQQE-HSDKEEVRSLVTWGNYAWVYYHMDQLEEAQK 115 Query: 212 H---LCTYEKQICD----KLAVEET---KGELLLQLCRL--EDAADVYRGLQERNPENWA 259 + + K++ KL ET KG LL+ + A + E P+N Sbjct: 116 YTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPE 175 Query: 260 YYKGL-EKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNF 318 + G + + + L P R + + + FL + Sbjct: 176 FNIGYAITVYRLDDSDREGSVKS-------FSLGPLRKAVTLNPDNSY---IKVFLALKL 225 Query: 319 SKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQY 378 + ++ + E IEE++ D P +V Sbjct: 226 -----------QDVHAEAEGEKYIEEIL-----------------DQISSQP----YVLR 253 Query: 379 YLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAG-NIKEAARWMDEAQAL 437 Y A+ Y + + ALE + A+E TPT L Y+ IK+A + + Sbjct: 254 YAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDK 313 Query: 438 DTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKA 497 D I+S + K A E S F A +L M Q A+ Sbjct: 314 LKVDELISSAIFHF-------KAAMERDSMF----AFAYTDLANMYAEGGQYSNAEDIFR 362 Query: 498 MNKFGEALKKCHEIERHFIEITDDQF-DFHTYCMRKITLRSYVDLLKLEDV 547 L+ + +H I +F +FH + Y++ LK++D Sbjct: 363 K---ALRLENITDDHKHQIHYHYGRFQEFHRKS-ENTAIHHYLEALKVKDR 409 >5EFR-A nrPDB Length = 446 Score = 29.4 bits (64), Expect = 6.8, Method: Composition-based stats. Identities = 37/230 (16%), Positives = 71/230 (30%), Gaps = 36/230 (15%) Query: 381 AQHYDKIGQPSIALEYINTAIESTPT-----LIELFLVKAKIYKHAGNIKEAARWMDEAQ 435 A + G+ A+EY T + +L +A Y++ + A+ + Q Sbjct: 207 AMEFYNQGKYDRAIEYFKAVFTYGRTHEWAADAQFYLARA-YYQNKEYLLAASEYERFIQ 265 Query: 436 --ALDT---ADRFINSKC-----AKYMLKANLIKEAEEMCSKF---------TREGTSAV 476 +D + + C Y L ++A E F + T + Sbjct: 266 IYQIDPRVPQAEYERAMCYYKLSPPYELDQTDTRKAIEAFQLFIDRYPNHELVDDATQKI 325 Query: 477 ENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIE--ITDDQFDFHTYCMRKIT 534 L + Q E A+ Y+ + A + + + DD Sbjct: 326 RELR-AKLARKQYEAARLYERRELYEAAAVTYEAVFDAYPDTPWADDAL--------VGA 376 Query: 535 LRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADT 584 +R+Y+ + RQ Y +A + + D+PL +E Sbjct: 377 MRAYIAYAEQSVRARQPERYRRAVELYERLLQIFPDSPLLRTAEELYTRA 426 >1VPM-A nrPDB Length = 169 Score = 29.4 bits (64), Expect = 8.0, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 31/84 (36%), Gaps = 13/84 (15%) Query: 545 EDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADT------ANMSDK-------E 591 D L F R ++E+Y+++H N L + ++ + S K E Sbjct: 83 GDALELEGFVTHTGRTSMEVYVRVHSNNLLTGERTLTTESFLTMVAVDESGKPKPVPQVE 142 Query: 592 LKKLRNKQRRAQKKAQIEEEKKNA 615 + K+ A+ E KK A Sbjct: 143 PQTEEEKRLYETAPARKENRKKRA 166 >1A17-A nrPDB Length = 166 Score = 29.4 bits (64), Expect = 8.0, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 7/84 (8%) Query: 94 KKYDEAIKCYRNALKWDKDNLQIL--RDLSLLQIQ-----MRDLEGYRETRYQLLQLRPA 146 K Y+ AIK Y A++ + N R L+ L+ + + D E + ++ Sbjct: 27 KDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYR 86 Query: 147 QRASWIGYAIAYHLLEDYEMAAKI 170 + AS + L DYE K+ Sbjct: 87 RAASNMALGKFRAALRDYETVVKV 110 >5JWG-A nrPDB Length = 703 Score = 29.0 bits (63), Expect = 9.5, Method: Composition-based stats. Identities = 10/86 (11%), Positives = 31/86 (36%) Query: 269 KPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNT 328 + +E+ ++ T+Y + + P++ G ++ M F K Sbjct: 424 DYSPEVEKDQLAIALLTRYAERIPAEKQPISIREGIAEYGSAKAYVEMIFDKSIYASRER 483 Query: 329 LRSLYKDKEKVAIIEELVVGYETSLK 354 K+ ++ ++ + + + S+ Sbjct: 484 FEEFMKNPDRDRLLRDPMSRFAASVA 509 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.126 0.322 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,638,792 Number of Sequences: 36641 Number of extensions: 1136422 Number of successful extensions: 5287 Number of sequences better than 10.0: 79 Number of HSP's better than 10.0 without gapping: 81 Number of HSP's successfully gapped in prelim test: 116 Number of HSP's that attempted gapping in prelim test: 4462 Number of HSP's gapped (non-prelim): 661 length of query: 866 length of database: 10,336,785 effective HSP length: 106 effective length of query: 760 effective length of database: 6,452,839 effective search space: 4904157640 effective search space used: 4904157640 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 63 (28.9 bits)