BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BXD5 (320 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6ARH-A nrPDB 652 0.0 5AFD-A nrPDB 206 1e-53 4N4Q-A nrPDB 129 1e-30 3LCG-A nrPDB 127 8e-30 5LKY-A nrPDB 107 5e-24 5ZKA-A nrPDB 107 5e-24 4WOQ-A nrPDB 107 6e-24 4IMD-A nrPDB 107 8e-24 1F73-A nrPDB 105 2e-23 5J5D-A nrPDB 105 2e-23 5UD6-A nrPDB 104 4e-23 1XKY-A nrPDB 101 4e-22 5KTL-A nrPDB 101 4e-22 3PUD-A nrPDB 100 8e-22 2EHH-A nrPDB 97 1e-20 4PTN-A nrPDB 95 4e-20 3N2X-A nrPDB 94 6e-20 3CPR-A nrPDB 93 2e-19 3FLU-A nrPDB 91 7e-19 2YXG-A nrPDB 90 1e-18 3S5N-A nrPDB 87 7e-18 6MQH-A nrPDB 86 1e-17 4I7U-A nrPDB 86 2e-17 1W37-A nrPDB 85 4e-17 2NUX-A nrPDB 85 4e-17 4FHA-A nrPDB 85 5e-17 2VC6-A nrPDB 84 8e-17 2R91-A nrPDB 80 1e-15 3IRD-A nrPDB 76 2e-14 4PFM-A nrPDB 75 4e-14 3DI0-A nrPDB 75 4e-14 2RFG-A nrPDB 75 5e-14 3NA8-A nrPDB 74 1e-13 4MLJ-A nrPDB 72 2e-13 3G0S-A nrPDB 72 5e-13 3SI9-A nrPDB 71 5e-13 3PS7-A nrPDB 71 6e-13 6NVA-A nrPDB 70 1e-12 4UXD-A nrPDB 69 2e-12 3PB0-A nrPDB 69 2e-12 5C54-A nrPDB 67 1e-11 4NQ1-A nrPDB 67 1e-11 4XKY-B nrPDB 59 2e-09 5UI3-D nrPDB 58 6e-09 3D0C-A nrPDB 52 3e-07 3TUU-A nrPDB 49 3e-06 4DPQ-A nrPDB 47 1e-05 2HMC-A nrPDB 43 2e-04 4DVY-P nrPDB 33 0.18 4UR8-A nrPDB 32 0.51 5CM5-A nrPDB 31 0.74 2FD5-A nrPDB 28 4.3 >6ARH-A nrPDB Length = 338 Score = 652 bits (1682), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/320 (100%), Positives = 320/320 (100%) Query: 1 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 60 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV Sbjct: 19 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 78 Query: 61 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 120 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT Sbjct: 79 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 138 Query: 121 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 180 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL Sbjct: 139 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 198 Query: 181 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 240 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS Sbjct: 199 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 258 Query: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL Sbjct: 259 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 318 Query: 301 KSLDFLSFTDLKDGNLEAGS 320 KSLDFLSFTDLKDGNLEAGS Sbjct: 319 KSLDFLSFTDLKDGNLEAGS 338 >5AFD-A nrPDB Length = 300 Score = 206 bits (524), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 120/301 (39%), Positives = 169/301 (56%), Gaps = 6/301 (1%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 KKL GL+AA TP + +NF I + +L+ + GVK I+V GTTGEG+ SV ER+ Sbjct: 2 KKLTGLIAAPHTPFDSSSNVNFEEIDKIAKHLIND-GVKGIYVCGTTGEGIHCSVEERKA 60 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 +AE WV+ KLD +I+H GALS+ ++ EL +HA + + I P F KP + L+ Sbjct: 61 IAERWVSACNHKLD-IIVHTGALSIVDTLELTRHADTLDILATSAIGPCFFKPGSVSDLV 119 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 + +AAAAP+ FYYYH ++GV + EE L +IP GLKF+ DL ++ +C Sbjct: 120 EYCATIAAAAPSKGFYYYH-SGMSGVNLNMEEFLIQADKRIPNLSGLKFNSGDLYEYQRC 178 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + + +F FGVDE L AL +GA AVGSTYNY N ++EAF + D N Sbjct: 179 L-RACDGKFDVPFGVDEFLPGALAVGAKSAVGSTYNYAAPHFNSIIEAFNKGDHDAVFNK 237 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDF 305 + I +V+ G GV+ K M L I G PRLPL S E + K+++ +F Sbjct: 238 MTNVIELIRVLVEFG-GVAAGKIAMEL-HDINAGDPRLPLMPLSAEQKLTVVEKMRAANF 295 Query: 306 L 306 L Sbjct: 296 L 296 >4N4Q-A nrPDB Length = 296 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 85/285 (29%), Positives = 155/285 (54%), Gaps = 9/285 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 K +GL A +TP T++G+++ + + + V++LV++Q V I++ G+TGE L LS ++++V Sbjct: 6 KFKGLFPAMVTPFTKDGKLHKAGVKEVVNFLVEKQKVDGIYITGSTGEFLLLSFEDKKEV 65 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + V + +I +G+L+++E++ELA+ A E+ D I+ I P++ ++ + + Sbjct: 66 M-KLVAEANAGRVTLIAQIGSLNIEETKELAKLAKELKYDAISAITPYYYN-FSFNETHH 123 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 + +E++ AA +P Y++P L G K+ ++ G L +I G K+ TDL F + + Sbjct: 124 YYEEISKAAD-IPMLIYYLPQLAGQKVSTDQF--GKLLEIKNVIGSKYGATDLFAFERLM 180 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + + F+F DE L L MGA G +GSTYN K N +++A+E D + Sbjct: 181 SKYPDK--LFMFAWDEALAMGLTMGAKGFIGSTYNVNAKGANAIIKAWEANDKEAVMKLT 238 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASRE 291 ++ ++ G + KAIM L G+ G R P + E Sbjct: 239 HTYNDYVLDLISKGL-MQSLKAIMRL-HGVDAGYTRKPFWRYEDE 281 >3LCG-A nrPDB Length = 319 Score = 127 bits (318), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 85/279 (30%), Positives = 144/279 (51%), Gaps = 13/279 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 L+G++AA +TP + ++ + + + V + + +QG+ ++V G+TGE S+SER QV Sbjct: 27 LRGVMAALLTPFDQQQALDKASLRRLVQFNI-QQGIDGLYVGGSTGEAFVQSLSEREQVL 85 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 E + K K+ ++I HVG +S ESQ+LA A G D ++ + PF+ P++ + + Sbjct: 86 EIVAEEAKGKI-KLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYY-PFSFEEHCDH 143 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + + +A LP Y+IPAL+GVK+ +++ L +P LK + DL Q Sbjct: 144 YRAIIDSADGLPMVVYNIPALSGVKLTLDQI--NTLVTLPGVGALKQTSGDLYQMEQI-- 199 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQF 247 + G DE S L+ GA G +GSTYN +G + +++A ++ D A Q Sbjct: 200 RREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQT 259 Query: 248 CIQRFINFVVKLGF--GVSQTKAIMTLVS----GIPMGP 280 + I+ ++K G G+ M +VS P GP Sbjct: 260 ECNKVIDLLIKTGLFRGLKTVLHYMDVVSVPLCRKPFGP 298 >5LKY-A nrPDB Length = 300 Score = 107 bits (268), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 87/302 (28%), Positives = 148/302 (49%), Gaps = 22/302 (7%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 K L+GL AA + P ENG++N + Q ++ + + ++VNG++GE L+ +++Q Sbjct: 10 KDLKGLYAALLVPFDENGQVNEQGLKQIAQNAIETEELDGLYVNGSSGENFLLNTEQKKQ 69 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 V + DK+ ++I VG+L L E+ EL ++A E+G D ++ + PF+ P+T + + Sbjct: 70 VFKVAKEAVGDKV-KLIAQVGSLDLNEAIELGKYATELGYDALSAVTPFYY-PFTFEEIR 127 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 ++ ++ A Y IP LTGV I E+ + L G+K++ + Sbjct: 128 DYYFDIIEATQN-NMIIYAIPDLTGVNISIEQFSE--LFNHEKIVGVKYTAPNFF----L 180 Query: 186 VDQNRQQQFAF-----LFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 240 +++ R+ AF L G DE L+ A + G GA+GSTYN G++ ++ + Q Sbjct: 181 LERIRK---AFPDKLILSGCDEMLVQATISGVDGAIGSTYNVNGRRARKIFDLARQGQIQ 237 Query: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQ---KASREFTDSAE 297 A Q I V L G+ T + GI G P+ P + +A R+ D Sbjct: 238 EAYQLQHDSNDIIETV--LSMGIYPTLKEILRHRGIDAGLPKRPFKPFNEAHRQTLDQLI 295 Query: 298 AK 299 AK Sbjct: 296 AK 297 >5ZKA-A nrPDB Length = 307 Score = 107 bits (268), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 81/287 (28%), Positives = 140/287 (48%), Gaps = 15/287 (5%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 ++G+ +A + P E+G IN + + + Y + + V ++V G+TGE +S E+++V Sbjct: 18 MKGIYSALMVPYNEDGSINEKGLREIIRYNIDKMKVDGLYVGGSTGENFMISTEEKKRVF 77 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLK---PWTKDIL 124 E + + KD ++ +I VG+++L E+ EL ++ ++G ++ + PF+ K KD Sbjct: 78 EIAIDEAKDSVN-LIAQVGSINLNEAVELGKYVTKLGYKCLSAVTPFYYKFDFSEIKDYY 136 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 ++E Y IP LTGV + + G L + G+KF+ D + Sbjct: 137 ETIVRETGNYMII-----YSIPFLTGVNMSLSQF--GELFENEKIIGVKFTAGDFYLL-E 188 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 V + + F G DE LL A V+G GA+GSTYN G + Q+ E + AL Sbjct: 189 RVRKAFPDKLIFA-GFDEMLLPATVLGVDGAIGSTYNINGIRAKQIFELAKNSKIDEALK 247 Query: 245 YQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASRE 291 Q I + L G+ QT + + G+ G R P++K S++ Sbjct: 248 IQHTTNDLIEGI--LSNGLYQTIKEILKLEGVDAGYCRKPMKKISQK 292 >4WOQ-A nrPDB Length = 302 Score = 107 bits (268), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 83/292 (28%), Positives = 148/292 (50%), Gaps = 13/292 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 ++G+ +A + + G IN + Q + + + V ++V G+TGE LS E++++ Sbjct: 15 MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGSTGENFMLSTDEKKRIF 74 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 E + K+++ ++I VG+++LKE+ ELA+ ++G D I+ + PF+ K ++I + Sbjct: 75 EIAKDEVKEEI-KLIAQVGSVNLKEAVELAKFTTDLGYDAISAVTPFYYKFDFEEIKHYY 133 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTD--LLDFGQC 185 + + L Y IP LTGV + ++ G L + G+KF+ D LL+ + Sbjct: 134 NTIINSVDNRLIIY--SIPFLTGVDMSLDQF--GELFENEKIIGVKFTAADFYLLERMRK 189 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 N+ G DE +L A V+G GA+GST+N G + Q+ E + + S AL Sbjct: 190 TFPNK----LIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFELTKNEKISEALEV 245 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAE 297 Q I + LG G+ QT ++ G+ G R P+++A+ E A+ Sbjct: 246 QHVTNDLITDI--LGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEMKSRAK 295 >4IMD-A nrPDB Length = 293 Score = 107 bits (266), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 86/300 (28%), Positives = 144/300 (48%), Gaps = 11/300 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 K L+G+ +A + +G IN + Q V Y + + V ++V G+TGE LS E+++ Sbjct: 2 KNLKGIFSALLVSFNADGSINEKGLRQIVRYNIDKMKVDGLYVGGSTGENFMLSTEEKKE 61 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + + KD++ +I VG+++L+E+ EL ++A E+G D ++ + PF+ K +I Sbjct: 62 IFRIAKDEAKDEI-ALIAQVGSVNLQEAIELGKYATELGYDSLSAVTPFYYKFSFPEIKH 120 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 + + A + Y IP LTGV I E+ G L K P G+KF+ D + Sbjct: 121 YYDSIIEATGNYMIV--YSIPFLTGVNIGVEQF--GELYKNPKVLGVKFTAGDFYLLERL 176 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + G DE +L A +G GA+GST+N G + Q+ E + AL Sbjct: 177 --KKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTQAGKLKEALEI 234 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQK--ASREFTDSAEAKLKSL 303 Q I ++ G ++ K ++ L G+ G R P+ K +S + + E K K L Sbjct: 235 QHVTNDLIEGILANGLYLT-IKELLKL-DGVEAGYCREPMTKELSSEKVAFAKELKAKYL 292 >1F73-A nrPDB Length = 293 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 88/306 (28%), Positives = 146/306 (47%), Gaps = 18/306 (5%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 + L+G+ +A + E+G IN + Q + + + + V ++V G+TGE LS E+++ Sbjct: 2 RDLKGIFSALLVSFNEDGTINEKGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTEEKKE 61 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLK---PWTKD 122 + + KD++ +I VG+++LKE+ EL ++A E+G D ++ + PF+ K P K Sbjct: 62 IFRIAKDEAKDQI-ALIAQVGSVNLKEAVELGKYATELGYDCLSAVTPFYYKFSFPEIKH 120 Query: 123 ILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDF 182 + E + Y IP LTGV + E+ G L K P G+KF+ D Sbjct: 121 YYDTIIAETGS-----NMIVYSIPFLTGVNMGIEQF--GELYKNPKVLGVKFTAGDFYLL 173 Query: 183 GQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA 242 + + G DE +L A +G GA+GST+N G + Q+ E + A Sbjct: 174 ERL--KKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTKAGKLKEA 231 Query: 243 LNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPL-QKASREFTDSAEAKLK 301 L Q I ++ G ++ K ++ L G+ G R P+ KA+ E A+AK Sbjct: 232 LEIQHVTNDLIEGILANGLYLT-IKELLKL-EGVDAGYCREPMTSKATAE--QVAKAKDL 287 Query: 302 SLDFLS 307 FLS Sbjct: 288 KAKFLS 293 >5J5D-A nrPDB Length = 300 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 84/300 (28%), Positives = 139/300 (46%), Gaps = 11/300 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +L L+ A +TP + +G ++ + + ++LV +QG + V+GTTGE + + E+ ++ Sbjct: 11 RLGTLLTAMVTPFSGDGSLDTATAARLANHLV-DQGCDGLVVSGTTGESPTTTDGEKIEL 69 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + D+ +VI G S LA+ A GA G+ V+ P++ KP + + + Sbjct: 70 LRAVLEAVGDRA-RVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAH 128 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F A A LP Y IP + V I + + L P G+K + DL Q + Sbjct: 129 F--TAVADATELPMLLYDIPGRSAVPIEPDTIR--ALASHPNIVGVKDAKADLHSGAQIM 184 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 A+ G D L L MGATG + + + ++L AF D + A Sbjct: 185 ADT---GLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKIN 241 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 + N + +LG GV+ +KA + L GI +G PRLP A+ E D+ A +++ L Sbjct: 242 IAVAPLCNAMSRLG-GVTLSKAGLRL-QGIDVGDPRLPQVAATPEQIDALAADMRAASVL 299 >5UD6-A nrPDB Length = 327 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 85/304 (27%), Positives = 142/304 (46%), Gaps = 20/304 (6%) Query: 4 PKKKLQGLVAATITPMTENG-EINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSE 62 PK ++ A +TP G E+++ V +L E G I V GTTGE +L+ SE Sbjct: 24 PKHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLA-ENGSDAIIVAGTTGESATLTWSE 82 Query: 63 RRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKD 122 ++ + +VI G+ S +E+ E + +A++G DG + P++ KP + Sbjct: 83 EYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQG 142 Query: 123 ILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDF 182 I+ +F + +A AAP LP Y+IP TG+ + AE + + + P LK + +L F Sbjct: 143 IMAHF-RAIANAAPDLPMMLYNIPGRTGINMTAETSIK-LAEMCPNIVALKEASGNLEQF 200 Query: 183 GQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAF-----EQK 237 + + + FA G D L L +G G V +++G + +M+E F ++ Sbjct: 201 AR-IRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEE 259 Query: 238 DFSLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAE 297 F + Y + + KA + L+ G P+GP RLPL + T SAE Sbjct: 260 AFRIHCRYMDLFEALFVMANPI-----PAKAALRLL-GWPVGPTRLPLT----DITASAE 309 Query: 298 AKLK 301 +L+ Sbjct: 310 QQLR 313 >1XKY-A nrPDB Length = 301 Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 82/294 (27%), Positives = 143/294 (48%), Gaps = 11/294 (3%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 + A +TP NG I+F+ + V+YL+ + G I V GTTGE +L+ SE + Sbjct: 16 IATAMVTPFDINGNIDFAKTTKLVNYLI-DNGTTAIVVGGTTGESPTLT-SEEKVALYRH 73 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 V DK VI G+ + S +L + A E+G D + ++AP++ KP + + +F K Sbjct: 74 VVSVVDKRVPVIAGTGSNNTHASIDLTKKATEVGVDAVMLVAPYYNKPSQEGMYQHF-KA 132 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 +A + P LP Y++P + V+I + ++ L +I +K + D+L + +++ Sbjct: 133 IAESTP-LPVMLYNVPGRSIVQISVDTVVR--LSEIENIVAIKDAGGDVLTMTEIIEKT- 188 Query: 191 QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQ 250 FA G D L A+ +GA G V + +G + +M+ AF+ +F A Q Q Sbjct: 189 ADDFAVYSGDDGLTLPAMAVGAKGIVSVASHVIGNEMQEMIAAFQAGEFKKA---QKLHQ 245 Query: 251 RFINFVVKLGFGVSQTKAIMTL-VSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + L S T L + G+ +G RLPL + E + ++ ++S+ Sbjct: 246 LLVRVTDSLFMAPSPTPVKTALQMVGLDVGSVRLPLLPLTEEERVTLQSVMQSI 299 >5KTL-A nrPDB Length = 330 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 83/300 (27%), Positives = 138/300 (46%), Gaps = 16/300 (5%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE- 69 ++ A ITP +G +N++V + +LV + G + V GTTGE +LS E + E Sbjct: 43 VLTAMITPFKADGSVNYAVAAELAAHLV-DNGTDTLVVCGTTGESPTLSWDEEYNLFVEV 101 Query: 70 -WVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 GK K VI G+ S KE+ Q AA+IG G + P++ KP + +F Sbjct: 102 LQTVAGKAK---VIAGCGSNSTKEAIAATQKAAKIGVHGTLQVVPYYNKPPQAGLYQHF- 157 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQ 188 + +A A P LP Y++P TG + E ++ L +I G+K + +L G+ + + Sbjct: 158 QAIAQACPDLPLLLYNVPGRTGQNLSPETVVR--LAEIDNIIGVKEASGNLDQAGE-IRR 214 Query: 189 NRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFC 248 + ++F G D L L +GA G V + +G + QM++AF ++A + Sbjct: 215 STPKEFQIYAGDDSLTLPLLAIGAKGVVSVASHLVGNQLQQMIQAFNSGQVTVASDIHLR 274 Query: 249 IQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 + F+ + Q + G +G R PL A E + EA +K L+ + Sbjct: 275 LLPLFKALFITTNPIPIKQALKL----QGWEVGSTRPPLSDADAEVSQKLEAVMKHLNLI 330 >3PUD-A nrPDB Length = 291 Score = 100 bits (249), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 85/297 (28%), Positives = 144/297 (48%), Gaps = 15/297 (5%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 +QG + A +TPM ++G +++ + + V++ + EQG +I GTTGE +LS+ E QV Sbjct: 2 IQGSIVAIVTPMLKDGGVDWKSLEKLVEWHI-EQGTNSIVAVGTTGEASTLSMEEHTQVI 60 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 +E + + +K +I GA S +E+ EL + A ++GAD ++ P++ KP T++ L Sbjct: 61 KE-IIRVANKRIPIIAGTGANSTREAIELTKAAKDLGADAALLVTPYYNKP-TQEGLYQH 118 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 K +A A LP Y++P TGV + + + L +IP G+K + D + G+ + Sbjct: 119 YKAIAEAV-ELPLILYNVPGRTGVDLSNDTAVR--LAEIPNIVGIKDATGD-VPRGKALI 174 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA--LNY 245 + A G DE +++GA G + T N K +++ KD A LN Sbjct: 175 DALNGKMAVYSGDDETAWELMLLGADGNISVTANIAPKAMSEVCAVAIAKDEQQAKTLNN 234 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLV-SGIPMGPPRLPLQKASREFTDSAEAKLK 301 + I F V M L+ +GI RLPL + ++ + LK Sbjct: 235 KIANLHNILFCESNPIPVKWALHEMGLIDTGI-----RLPLTPLAEQYREPLRNALK 286 >2EHH-A nrPDB Length = 294 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 78/299 (26%), Positives = 139/299 (46%), Gaps = 13/299 (4%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 QG + A ITP E GE+++ +G +++ V + G I V GTTGE +L+ E +V E Sbjct: 3 QGSIVALITPFKE-GEVDYEALGNLIEFHV-DNGTDAILVCGTTGESPTLTFEEHEKVIE 60 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 V + ++ +VI G + E+ L HA E+GADG V+ P++ KP + + +F Sbjct: 61 FAVKRAAGRI-KVIAGTGGNATHEAVHLTAHAKEVGADGALVVVPYYNKPTQRGLYEHF- 118 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQ 188 + A +P Y+IP+ T V+I + + + + K S ++ + V + Sbjct: 119 -KTVAQEVDIPIIIYNIPSRTCVEISVDTMFK-LASECENIVASKESTPNMDRISEIV-K 175 Query: 189 NRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFC 248 + F+ L G D L + +GA G + N + ++ +++ A + DF A Sbjct: 176 RLGESFSVLSGDDSLTLPMMALGAKGVISVANNVMPREVKELIRAALEGDFRRARE---- 231 Query: 249 IQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPP--RLPLQKASREFTDSAEAKLKSLDF 305 I +++ + K+ F + + T + M RLPL + S E + LK + Sbjct: 232 IHYYLHDLFKVLFIETNPIPVKTACWMLGMCEKEFRLPLTEMSPENENKLREVLKKYNL 290 >4PTN-A nrPDB Length = 343 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 118/239 (49%), Gaps = 7/239 (2%) Query: 10 GLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE 69 G++ T T +G+++ +D L+K GV +F G+ GE L ER+ +A Sbjct: 34 GIIPPVSTIFTADGQLDKPGTAALIDDLIKA-GVDGLFFLGSGGEFSQLGAEERKAIAR- 91 Query: 70 WVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLK 129 + D+ V+I G + +E+ EL+QHA + GADGI VI P++ K ++ LI + + Sbjct: 92 FAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWK-VSEANLIRYFE 150 Query: 130 EVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD-- 187 +VA + LP Y+ PALTG + L+ + D G+K + + + Sbjct: 151 QVADSV-TLPVMLYNFPALTGQDL-TPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTV 208 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F L G D+ L + L++G GA+ ++ N+ + + +L+A+ D + A Y Sbjct: 209 KGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYH 267 >3N2X-A nrPDB Length = 298 Score = 94.4 bits (233), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 118/239 (49%), Gaps = 7/239 (2%) Query: 10 GLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE 69 G++ T T +G+++ +D L+K GV +F G+ GE L ER+ +A Sbjct: 5 GIIPPVSTIFTADGQLDKPGTAALIDDLIKA-GVDGLFFLGSGGEFSQLGAEERKAIAR- 62 Query: 70 WVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLK 129 + D+ V+I G + +E+ EL+QHA + GADGI VI P++ K ++ LI + + Sbjct: 63 FAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWK-VSEANLIRYFE 121 Query: 130 EVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD-- 187 +VA + LP Y+ PALTG + L+ + D G+K + + + Sbjct: 122 QVADSV-TLPVMLYNFPALTGQDL-TPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTV 179 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F L G D+ L + L++G GA+ ++ N+ + + +L+A+ D + A Y Sbjct: 180 KGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYH 238 >3CPR-A nrPDB Length = 304 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 80/293 (27%), Positives = 147/293 (50%), Gaps = 11/293 (3%) Query: 14 ATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTK 73 A +TP TE+G+I+ + + YLV ++G+ ++ + GTTGE + + +E+ ++ + + Sbjct: 23 AMVTPFTESGDIDIAAGREVAAYLV-DKGLDSLVLAGTTGESPTTTAAEKLELLKAVREE 81 Query: 74 GKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKEVAA 133 D+ ++I VG + + S ELA+ AA GADG+ V+ P++ KP + +L +F A Sbjct: 82 VGDRA-KLIAGVGTNNTRTSVELAEAAASAGADGLLVVTPYYSKPSQEGLLAHF--GAIA 138 Query: 134 AAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNRQQQ 193 AA +P Y IP +G+ I ++ + L ++PT +K + DL+ + ++ Sbjct: 139 AATEVPICLYDIPGRSGIPIESDTMRR--LSELPTILAVKDAKGDLVAATSLI---KETG 193 Query: 194 FAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQRFI 253 A+ G D L L +G +G + + ++ +FE+ D A + + Sbjct: 194 LAWYSGDDPLNLVWLALGGSGFISVIGHAAPTALRELYTSFEEGDLVRAREINAKLSPLV 253 Query: 254 NFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 +LG GVS KA + L GI +G PRLP+ + + ++ +K L Sbjct: 254 AAQGRLG-GVSLAKAALRL-QGINVGDPRLPIMAPNEQELEALREDMKKAGVL 304 >3FLU-A nrPDB Length = 297 Score = 90.9 bits (224), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 114/239 (47%), Gaps = 7/239 (2%) Query: 4 PKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER 63 P LQG + A ITPM ++G I++ + +D+ + E G I GTTGE +LSV E Sbjct: 4 PFTMLQGSLVALITPMNQDGSIHYEQLRDLIDWHI-ENGTDGIVAVGTTGESATLSVEEH 62 Query: 64 RQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDI 123 V E V K K VI GA + E+ L+Q A + GAD + P++ KP + I Sbjct: 63 TAVIEA-VVKHVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGI 121 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 +F + A A ++P Y++P T V + + +L L +IP G+K + ++ Sbjct: 122 YQHF--KTIAEATSIPMIIYNVPGRTVVSMTNDTILR--LAEIPNIVGVKEASGNIGSNI 177 Query: 184 QCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA 242 + +++ + F L G D L ++ G G + N K M A Q D +LA Sbjct: 178 ELINR-APEGFVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMCRAALQGDIALA 235 >2YXG-A nrPDB Length = 289 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 80/300 (26%), Positives = 141/300 (47%), Gaps = 15/300 (5%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 +G+ A ITP +N E++F + + +++L+ E GV I GTTGE +LS E ++V E Sbjct: 3 KGVYPAIITPF-KNKEVDFDGLEENINFLI-ENGVSGIVAVGTTGESPTLSHEEHKKVIE 60 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 + V ++ QVI G+ +E+ EL+ A ++GAD + I P++ KP + + +F Sbjct: 61 KVVDVVNGRV-QVIAGAGSNCTEEAIELSVFAEDVGADAVLSITPYYNKPTQEGLRKHFG 119 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQ 188 K A + LP Y++P+ T V + + + + ++ +K ++ +L + + Sbjct: 120 K--VAESINLPIVLYNVPSRTAVNLEP-KTVKLLAEEYSNISAVKEANPNLSQVSELI-- 174 Query: 189 NRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA--LNYQ 246 + L G DE L + +G G + N + K+ +M+ + DF A ++Y+ Sbjct: 175 -HDAKITVLSGNDELTLPIIALGGKGVISVVANIVPKEFVEMVNYALEGDFEKAREIHYK 233 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 F+ V +M G P G RLPL + S E E LK L + Sbjct: 234 LFPLMKAMFIETNPIPVKTALNMM----GRPAGELRLPLCEMSEEHKKILENVLKDLGLI 289 >3S5N-A nrPDB Length = 304 Score = 87.4 bits (215), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 84/306 (27%), Positives = 135/306 (44%), Gaps = 17/306 (5%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K + G+ TP T E+++ + + + L + V G+ GE L+ SER Sbjct: 9 KVDIAGIYPPVTTPFTATAEVDYGKLEENLHKL-GTFPFRGFVVQGSNGEFPFLTSSERL 67 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLK-PWTKDI 123 +V V + K ++ G S + + E+ A++GAD V+ P + + + Sbjct: 68 EVVSR-VRQAMPKNRLLLAGSGCESTQATVEMTVSMAQVGADAAMVVTPCYYRGRMSSAA 126 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 LI+ +VA +P +P Y +PA TG+ + + ++ L + P G+K S D+ G Sbjct: 127 LIHHYTKVADLSP-IPVVLYSVPANTGLDLPVDAVV--TLSQHPNIVGMKDSGGDVTRIG 183 Query: 184 QCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243 V + R+Q F L G L+++ +GA G V + N LG + Q+ + A Sbjct: 184 LIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVCALANVLGAQVCQLERLCCTGQWEDAQ 243 Query: 244 NYQFCIQRFI--NFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLK 301 Q R I N V FG+ K IM G GP R PLQ+ S AE + Sbjct: 244 KLQ---HRLIEPNAAVTRRFGIPGLKKIMDWF-GYYGGPCRAPLQELS-----PAEEEAL 294 Query: 302 SLDFLS 307 +DF S Sbjct: 295 RMDFTS 300 >6MQH-A nrPDB Length = 308 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 62/236 (26%), Positives = 115/236 (48%), Gaps = 7/236 (2%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +++G V A +TPM E+G ++ + + +D+ + E+G + V GT+GE +LSV E + Sbjct: 18 QIRGSVPAIVTPMLEDGGLDLAAFRKLIDWHI-EEGTDALVVVGTSGESATLSVDEHVLM 76 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 E V ++ ++ G S E+ EL++HA +GAD + P++ KP + I + Sbjct: 77 IETAVKHAAKRI-PIVAGAGGNSTTEAIELSKHAKAVGADATLQVVPYYNKPTQEGIYRH 135 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F K +A A LP Y++P T + E L L ++P G+K + ++ Q + Sbjct: 136 F-KAIAEAVD-LPVILYNVPGRTVADMSNETTLR--LAQVPGIIGVKDATGNIDRAAQLI 191 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA 242 + F+ G D ++ +++G G + T N + +++ A D A Sbjct: 192 -KAAPAHFSIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAALAADVKTA 246 >4I7U-A nrPDB Length = 308 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 115/245 (46%), Gaps = 12/245 (4%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 +K +G + A ITP T+NG ++ +V++ + E G + GTTGE +LS E + Sbjct: 13 EKMFKGSIPALITPFTDNGAVDEQAFAAHVEWQIAE-GSNGLVPVGTTGESPTLSHDEHK 71 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 +V E + ++ VI G+ + E+ ELA HA + GAD + V+ P++ KP K + Sbjct: 72 RVVELCIEVAAKRV-PVIAGAGSNNTDEAIELALHAQDAGADALLVVTPYYNKPTQKGLF 130 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 +F A A LP Y+IP + V + + E + ++ G+K + T LD Sbjct: 131 AHF--SAVAEAVKLPIVIYNIPPRSVVDM-SPETMGALVKAHKNIVGVKDA-TGKLDR-- 184 Query: 185 CVDQNR---QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSL 241 V + R + F L G D L G G + + N + ++ A D++ Sbjct: 185 -VSEQRISCGKDFIQLSGEDSTALGFNAHGGVGCISVSANVAPRLCSEFQAAMLAGDYAK 243 Query: 242 ALNYQ 246 AL YQ Sbjct: 244 ALEYQ 248 >1W37-A nrPDB Length = 294 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 128/276 (46%), Gaps = 16/276 (5%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 ++ ITP T++ I+ + + + L++ +G+ +FVNGTTG G SLS E+ E Sbjct: 4 IITPIITPFTKDNRIDKEKLKIHAENLIR-KGIDKLFVNGTTGLGPSLSPEEKL----EN 58 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 + D +++I VG L+L ++ LA+ + + GIA AP++ ++ L+ + K Sbjct: 59 LKAVYDVTNKIIFQVGGLNLDDAIRLAKLSKDFDIVGIASYAPYYYPRMSEKHLVKYFKT 118 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 + +P P Y Y+ P TG I A+ + +I F G+K + +++ +D R Sbjct: 119 LCEVSPH-PVYLYNYPTATGKDIDAK-----VAKEIGCFTGVKDTIENII---HTLDYKR 169 Query: 191 QQQFAFLFGVDEQLLSALV-MGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCI 249 ++ + L++ + G G V + NYL + T + + ++ AL QF Sbjct: 170 LNPNMLVYSGSDMLIATVASTGLDGNVAAGSNYLPEVTVTIKKLAMERKIDEALKLQFLH 229 Query: 250 QRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPL 285 I G +S + G +G PR P+ Sbjct: 230 DEVIEASRIFG-SLSSNYVLTKYFQGYDLGYPRPPI 264 >2NUX-A nrPDB Length = 288 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 69/275 (25%), Positives = 127/275 (46%), Gaps = 16/275 (5%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 +++ ITP + G++N + + L+ E+G+ IFVNGTTG G +LS E+RQ Sbjct: 3 IISPIITPFDKQGKVNVDALKTHAKNLL-EKGIDAIFVNGTTGLGPALSKDEKRQNLNAL 61 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 D ++I VG+L+L + EL + + E+ G++ +P++ + L + +E Sbjct: 62 Y----DVTHKLIFQVGSLNLNDVMELVKFSNEMDILGVSSHSPYYFPRLPEKFLAKYYEE 117 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 +A + + Y Y+ PA TG I IL +P +G+K ++ DL ++ Sbjct: 118 IARIS-SHSLYIYNYPAATGYDIPP-----SILKSLPV-KGIKDTNQDL---AHSLEYKL 167 Query: 191 QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQ 250 ++ L+ ++ G V S N++ + + + +Q AL Q I Sbjct: 168 NLPGVKVYNGSNTLIYYSLLSLDGVVASFTNFIPEVIVKQRDLIKQGKLDDALRLQELIN 227 Query: 251 RFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPL 285 R + + K G +S ++ G +G PR P+ Sbjct: 228 RLADILRKYG-SISAIYVLVNEFQGYDVGYPRPPI 261 >4FHA-A nrPDB Length = 311 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 86/298 (28%), Positives = 140/298 (46%), Gaps = 23/298 (7%) Query: 1 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 60 M++ K ++ A ITP E+G INF I +++L+ I + GTT E +L+ Sbjct: 1 MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHH-TDGILLAGTTAESPTLTH 59 Query: 61 SERRQV--AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIG--ADGIAVIAPFFL 116 E ++ A + V G+ L I VG ++S E + AE G A G+A++ P++ Sbjct: 60 DEELELFAAVQKVVNGRVPL---IAGVGTNDTRDSIEFVKEVAEFGGFAAGLAIV-PYYN 115 Query: 117 KPWTKDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSD 176 KP + + +F K +A A+ LP Y+IP V++ E +L L P G+K Sbjct: 116 KPSQEGMYQHF-KAIADAS-DLPIIIYNIPGRVVVELTPETMLR--LADHPNIIGVK-EC 170 Query: 177 TDLLDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQ 236 T L + + +++ ++F G D A+ +GA G + + G + ++M A + Sbjct: 171 TSLANMAYLI-EHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFTAIAE 229 Query: 237 KDFSLALNYQFCIQRFINFVVKLGFGV---SQTKAIMTLVSGIPMGPPRLPLQKASRE 291 D A Q ++FI V L F + KAI+ + G GP RLPL A E Sbjct: 230 SDMKKAAAIQ---RKFIPKVNAL-FSYPSPAPVKAILNYM-GFEAGPTRLPLVPAPEE 282 >2VC6-A nrPDB Length = 292 Score = 84.0 bits (206), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 111/242 (45%), Gaps = 15/242 (6%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 +G + A +TP ++ I+ + V++ + E+G + GTTGE +LS SE QV E Sbjct: 3 EGSITALVTPFADD-RIDEVALHDLVEWQI-EEGSFGLVPCGTTGESPTLSKSEHEQVVE 60 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 + ++ VI G+ S E+ +HA GADG+ +++P++ KP + I +F Sbjct: 61 ITIKTANGRV-PVIAGAGSNSTAEAIAFVRHAQNAGADGVLIVSPYYNKPTQEGIYQHF- 118 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDL----LDFGQ 184 + AA +P Y+IP + ++I E L I + P +G+K + +L L+ Sbjct: 119 -KAIDAASTIPIIVYNIPGRSAIEIHVETLAR-IFEDCPNVKGVKDATGNLLRPSLERMA 176 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 C + F L G D L + G G + T N +A DF+ AL Sbjct: 177 C-----GEDFNLLTGEDGTALGYMAHGGHGCISVTANVAPALCADFQQACLNGDFAAALK 231 Query: 245 YQ 246 Q Sbjct: 232 LQ 233 >2R91-A nrPDB Length = 286 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 72/300 (24%), Positives = 141/300 (47%), Gaps = 28/300 (9%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 +VA IT G ++ + +V + +GV +FV GTTG G +LS+ E+ ++ + Sbjct: 3 IVAPVITTF-RGGRLDPELFANHVKN-ITSKGVDVVFVAGTTGLGPALSLQEKMELTDAA 60 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 + + +VI+ V +L+ E+ LA++A GA+ +A + P++ ++ + + ++ Sbjct: 61 TSAAR----RVIVQVASLNADEAIALAKYAESRGAEAVASLPPYYFPRLSERQIAKYFRD 116 Query: 131 VAAAAPALPFYYYHIPALTG--VKIRAEELLDGILDKIPTFQGLKFSDTDL---LDFGQC 185 + +A ++P + Y+ PA G V RA + L I +G+K ++ L L + + Sbjct: 117 LCSAV-SIPVFLYNYPAAVGRDVDARAAKELGCI-------RGVKDTNESLAHTLAYKRY 168 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + Q R G D + ++ + G V S+ NYL + + +A D A + Sbjct: 169 LPQARVYN-----GSDSLVFASFAVRLDGVVASSANYLPELLAGIRDAVAAGDIERARSL 223 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPR---LPLQKASREFTDSAEAKLKS 302 QF + + +G+ + + ++ + G G PR PL + + +A AK KS Sbjct: 224 QFLLDEIVESARHIGYAAAVYE-LVEIFQGYEAGEPRGPVYPLDPEEKAWLRAAVAKAKS 282 >3IRD-A nrPDB Length = 291 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 72/304 (23%), Positives = 136/304 (44%), Gaps = 22/304 (7%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 +G A ITP T G ++F + + +++ +K + I V GTTGE +++ +ER++ + Sbjct: 4 KGSGVAIITPFTNTG-VDFDKLSELIEWHIKSK-TDAIIVCGTTGEATTMTETERKETIK 61 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 +V +K VI G+ + S +++ A IG DG+ VI P++ K K ++ +F Sbjct: 62 -FVIDKVNKRIPVIAGTGSNNTAASIAMSKWAESIGVDGLLVITPYYNKTTQKGLVKHF- 119 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ---- 184 + + A + P Y++P TG+ I L + DK +K + ++ Q Sbjct: 120 -KAVSDAVSTPIIIYNVPGRTGLNITPGTLKELCEDK--NIVAVKEASGNISQIAQIKAL 176 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 C D + G D+Q++ L +G G + N + + + M E + + AL Sbjct: 177 CGD-----KLDIYSGNDDQIIPILALGGIGVISVLANVIPEDVHNMCELYLNGKVNEALK 231 Query: 245 YQFCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKS 302 Q N F+ V +M + +G RLPL + + + + +LK+ Sbjct: 232 IQLDSLALTNALFIETNPIPVKTAMNLMNM----KVGDLRLPLCEMNENNLEILKKELKA 287 Query: 303 LDFL 306 + + Sbjct: 288 YNLM 291 >4PFM-A nrPDB Length = 295 Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 74/287 (25%), Positives = 125/287 (43%), Gaps = 12/287 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 + G + A ITP+ +G ++++ + + V+Y + E G I GTTGE +L +SE V Sbjct: 3 INGSIVALITPLNSDGTVDYTSLEKLVEYHITE-GTDAIVAVGTTGESATLPISEHIAVV 61 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + V ++ VI GA + E+ EL + ++G + + P++ KP K ++ ++ Sbjct: 62 GQTVKFASGRI-PVIGGNGANATAEAIELTKAQNKLGVAAMLGVTPYYNKPSPKGLIAHY 120 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 AA+ +P Y++P T V + E + L ++P G+K + D+ Q D Sbjct: 121 --TAVAASTDIPQILYNVPGRTAVDMLPETIAQ--LVEVPNIIGVKDATGDVARVKQLRD 176 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQF 247 F G D L +G G + N + K M +A D A+ + Sbjct: 177 LC-GNDFLLYSGDDATAREFLTLGGDGVISVANNIVPKLFKLMCDAALAGDTQAAMAAED 235 Query: 248 CIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREF 292 I+ + F V M L+S G RLPL + S EF Sbjct: 236 QIKGLFSALFCEANPIPVKWAAHKMGLIS---QGDIRLPLTELSTEF 279 >3DI0-A nrPDB Length = 295 Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 63/228 (27%), Positives = 109/228 (47%), Gaps = 13/228 (5%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 +G+ A TP T N ++N + +V++L+ E + I VNGTT E +L+ E+ ++ + Sbjct: 6 EGVGVALTTPFT-NNKVNIEALKTHVNFLL-ENNAQAIIVNGTTAESPTLTTDEKERILK 63 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 V DK VI G ++S + + A +GAD I +I P++ K + ++ +F Sbjct: 64 -TVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKHF- 121 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTD---LLDFGQC 185 E A A LP Y++P+ T + I E + IL + P LK + D L + + Sbjct: 122 -EAIADAVKLPVVLYNVPSRTNMTIEPETV--EILSQHPYIVALKDATNDFEYLEEVKKR 178 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEA 233 +D N FA G D+ ++ G G + N + K+ + +A Sbjct: 179 IDTN---SFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDA 223 >2RFG-A nrPDB Length = 297 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 65/239 (27%), Positives = 111/239 (46%), Gaps = 14/239 (5%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 +G + A ITP NG+++ + VD+ +K G + GTTGE +L+ E ++V Sbjct: 3 RGSLIAMITPFI-NGQVDEKALAGLVDWQIK-HGAHGLVPVGTTGESPTLTEEEHKRVVA 60 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 + + ++ VI G+ + E+ AQHA + GAD + +A ++ +P + + +F Sbjct: 61 LVAEQAQGRVP-VIAGAGSNNPVEAVRYAQHAQQAGADAVLCVAGYYNRPSQEGLYQHF- 118 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQ 188 ++ A +P Y+IP V I+ E + L +P G+K + TDL + + Sbjct: 119 -KMVHDAIDIPIIVYNIPPRAVVDIKPETMAR--LAALPRIVGVKDATTDLAR----ISR 171 Query: 189 NR---QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 R + F+FL G D ++ G G + + N QM A Q DF AL Sbjct: 172 ERMLINKPFSFLSGDDMTAIAYNASGGQGCISVSANIAPALYGQMQTATLQGDFREALR 230 >3NA8-A nrPDB Length = 315 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 75/308 (24%), Positives = 136/308 (44%), Gaps = 30/308 (9%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 + G++ TITP +G ++ +G+ ++ L+ + GV I G+TGEG LS E +V Sbjct: 24 SIHGIIGYTITPFAADGGLDLPALGRSIERLI-DGGVHAIAPLGSTGEGAYLSDPEWDEV 82 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 ++ K I+ V L+ ++ AQ A +GA+ + V+ + K ++ + Sbjct: 83 V-DFTLKTVAHRVPTIVSVSDLTTAKTVRRAQFAESLGAEAVMVLPISYWKLNEAEVFQH 141 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 + A +P Y+ P +G+ + E +L I+ ++ +K S D+ Q + Sbjct: 142 Y--RAVGEAIGVPVMLYNNPGTSGIDMSVELILR-IVREVDNVTMVKESTGDI----QRM 194 Query: 187 DQNR---QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDF--SL 241 + R + + F G + L A V GA G + N + Q+ +A D + Sbjct: 195 HKLRLLGEGRVPFYNGCNPLALEAFVAGAKGWCSAAPNLIPTLNGQLYQAVLDGDLEKAR 254 Query: 242 ALNYQ------FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDS 295 AL Y+ F ++R + +K G G +SG+ +G PRLP+Q E Sbjct: 255 ALFYRQLPLLDFILRRGLPTTIKAGLG----------LSGLEVGAPRLPVQALDTEGCRY 304 Query: 296 AEAKLKSL 303 + L+ L Sbjct: 305 LQGLLEEL 312 >4MLJ-A nrPDB Length = 306 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 85/310 (27%), Positives = 133/310 (42%), Gaps = 20/310 (6%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K + G + A ITP +NG+++ + + + E G+ + GTTGE +L+ E R Sbjct: 11 KNIIIGAMTALITPF-KNGKVDEQSYARLIKRQI-ENGIDAVVPVGTTGESATLTHEEHR 68 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 E V K +V+ G+ + E+ LA+ A E GADGI +APF+ KP T+ L Sbjct: 69 TCIEIAVETCKGTKVKVLAGAGSNATHEAVGLAKFAKEHGADGILSVAPFYNKP-TQQGL 127 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 K +A + +P Y++P TG +I + ++ D G+K + ++ + Sbjct: 128 YEHYKAIAQSVD-IPVLLYNVPGRTGCEISTDTIIKLFRD-CENIYGVKEASGNI---DK 182 Query: 185 CVD-QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243 CVD + + + G D L G G + T N L M+ A F+L Sbjct: 183 CVDLLAHEPRMMLISGEDAINYPILSNGGKGVISVTSNLLP----DMISALTH--FALDE 236 Query: 244 NYQFC--IQRFINFVVKLGFGVSQ---TKAIMTLVSGIPMGPPRLPLQKASREFTDSAEA 298 NY+ I + + K+ F S K M L I RLPL S+E E Sbjct: 237 NYKEAKKINDELYNINKILFCESNPIPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEE 296 Query: 299 KLKSLDFLSF 308 +K F Sbjct: 297 VMKKYKIKGF 306 >3G0S-A nrPDB Length = 316 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 67/245 (27%), Positives = 105/245 (42%), Gaps = 15/245 (6%) Query: 10 GLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE 69 G + A +TPM E G ++ S + + +DY V G I GTTGE +LS E V Sbjct: 28 GSIVALVTPMDEKGNVSRSCLKKLIDYHVA-NGTSAIVSVGTTGESATLSHDEHGDVVMM 86 Query: 70 WVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLK 129 + ++ VI GA + E+ L Q + G G + P++ +P T++ L K Sbjct: 87 TLELADGRI-PVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRP-TQEGLFQHFK 144 Query: 130 EVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQN 189 +A LP Y++P+ TG + E + G L +I +K + +L Q + + Sbjct: 145 AIAEHTD-LPQILYNVPSRTGCDMLPETV--GRLAEIKNIIAIKEATGNLTRVHQ-IKEL 200 Query: 190 RQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCI 249 F L G D L + +G G + T N ++ M + LA QF Sbjct: 201 VSDDFILLSGDDASALDFMQLGGHGVISVTANVAAREMADMCK--------LAAEGQFAE 252 Query: 250 QRFIN 254 R IN Sbjct: 253 ARAIN 257 >3SI9-A nrPDB Length = 315 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 39/124 (31%), Positives = 69/124 (55%), Gaps = 2/124 (1%) Query: 4 PKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER 63 P L+G V A ITP +NG I+ +V++ + QG+ + GTTGE +L+ E Sbjct: 19 PGSMLKGAVTALITPFDDNGAIDEKAFCNFVEWQIT-QGINGVSPVGTTGESPTLTHEEH 77 Query: 64 RQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDI 123 +++ E V + ++ V+ G+ S E+ ELA+HA + GAD + V+ P++ +P + + Sbjct: 78 KRIIELCVEQVAKRV-PVVAGAGSNSTSEAVELAKHAEKAGADAVLVVTPYYNRPNQRGL 136 Query: 124 LINF 127 +F Sbjct: 137 YTHF 140 >3PS7-A nrPDB Length = 292 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 58/214 (27%), Positives = 104/214 (48%), Gaps = 7/214 (3%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 + G + A +TP G +++ + + VD+ +++ G I GTTGE +L V E QV Sbjct: 2 IAGSMVALVTPFDAQGRLDWDSLAKLVDFHLQD-GTNAIVAVGTTGESATLDVEEHIQVV 60 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 V + K ++ VI GA S +E+ L + A GAD ++ P++ KP T++ + Sbjct: 61 RRVVDQVKGRI-PVIAGTGANSTREAVALTEAAKSGGADACLLVTPYYNKP-TQEGMYQH 118 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + +A A A+P Y++P T + E + L K+P G+K + DL + ++ Sbjct: 119 FRHIAEAV-AIPQILYNVPGRTSCDMLPETVER--LSKVPNIIGIKEATGDLQRAKEVIE 175 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYN 221 + + F G D + +++G G + T N Sbjct: 176 R-VGKDFLVYSGDDATAVELMLLGGKGNISVTAN 208 >6NVA-A nrPDB Length = 294 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 75/308 (24%), Positives = 125/308 (40%), Gaps = 31/308 (10%) Query: 10 GLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE 69 G + A +TPM E G + + + + +DY V G I GTTGE +L+ E V Sbjct: 6 GSIVAIVTPMDEKGNVCRASLKKLIDYHVA-SGTSAIVSVGTTGESATLNHDEHADVVMM 64 Query: 70 WVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLK 129 + ++ VI GA + E+ L Q + G G + P++ +P + + +F Sbjct: 65 TLDLADGRI-PVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHF-- 121 Query: 130 EVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQN 189 + A LP Y++P+ TG + E + G L K+ G+ + +L Q + + Sbjct: 122 KAIAEHTDLPQILYNVPSRTGCDLLPETV--GRLAKVKNIIGIXEATGNLTRVNQ-IKEL 178 Query: 190 RQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCI 249 F L G D L + +G G + T N + QM + LA F Sbjct: 179 VSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCK--------LAAEGHFAE 230 Query: 250 QRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFLSFT 309 R IN + +M L + + + P +P++ A +E A L+ L T Sbjct: 231 ARVIN------------QRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLR----LPMT 274 Query: 310 DLKDGNLE 317 + D E Sbjct: 275 PITDSGRE 282 >4UXD-A nrPDB Length = 297 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 55/218 (25%), Positives = 111/218 (50%), Gaps = 9/218 (4%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K +G+V ITP+ +G I+++ + YL + V +F G+TG ++ ER+ Sbjct: 22 KHMYKGIVCPMITPLDAHGNIDYNATNILIKYL-EGINVDYLFPMGSTGVFPYFTLKERK 80 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 + +V + K ++ VG+ S+ E EL + + +IG + ++ P+++K ++ + Sbjct: 81 DFLK-FVRENSKK--PIMAGVGSSSINEVNELMKFSMDIGIEAAVLMPPYYIK-LNQEAI 136 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 ++ KE+ ++ + Y+IP T KI E + + + + +G+K S D+ F + Sbjct: 137 YHYYKEILSSN-DMDLLIYNIPQFTN-KIDPET-VKNLKSEFSSVKGVKDSSADIRGFME 193 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNY 222 + + FA G D+ L ++L +GA+G V T N+ Sbjct: 194 MLSLS-DDDFAVFQGQDDLLFTSLELGASGGVCGTTNF 230 >3PB0-A nrPDB Length = 300 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 82/311 (26%), Positives = 141/311 (45%), Gaps = 22/311 (7%) Query: 4 PKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER 63 P +G+ A +TP +NGE++ + V Y + E GV + V GTTGE +++ ER Sbjct: 4 PFTMFRGVGTAIVTPF-KNGELDLESYERLVRYQL-ENGVNALIVLGTTGESPTVNEDER 61 Query: 64 RQVAEEWVTKGKDKLD---QVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 120 E+ V++ + +D VI+ G S +++ +L + A ++GA+G+ V+ P++ KP T Sbjct: 62 ----EKLVSRTLEIVDGKIPVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTPYYNKP-T 116 Query: 121 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 180 ++ L K ++ L Y++P TGV + E I + G+K ++ Sbjct: 117 QEGLYQHYKYISERT-DLGIVVYNVPGRTGVNVLPETAAR-IAADLKNVVGIKEANPAAA 174 Query: 181 DFGQCVDQNRQQQFAFLF--GVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKD 238 + V +Q + F+ G D++ L G G + N K QM+E + Sbjct: 175 QIDRTVSLTKQARSDFMVWSGNDDRTFYLLCAGGDGVISVVSNVAPK---QMVELCAEY- 230 Query: 239 FSLALNYQFCIQRFINFVVKLGFGVSQ---TKAIMTLVSGIPMGPPRLPLQKASREFTDS 295 FS L + R + ++K F + KA + L+ G RLPL AS + + Sbjct: 231 FSGNLEKSREVHRKLRPLMKALFVETNPIPVKAALNLM-GFIENELRLPLVPASEKTVEL 289 Query: 296 AEAKLKSLDFL 306 LK L Sbjct: 290 LRNVLKESGLL 300 >5C54-A nrPDB Length = 312 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 15/214 (7%) Query: 10 GLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE 69 G++ +TP+ +G ++ + + VD+L+ GV +F G++GE L+ ++R+ Sbjct: 8 GVIPPVMTPLHADGSVDVESLRKLVDHLIN-GGVDGLFALGSSGEAAFLTRAQRKLALTT 66 Query: 70 WVTKGKDKLDQVIIHVGALSLKESQ--ELAQHAAEIGADGIAVIAPFFLKPWTKDILI-N 126 + + +V + G + ++ EL + A E GA+G+ APF+ + T D+ I Sbjct: 67 II---EHTAGRVPVTAGVIETTTARVIELVEDALEAGAEGLVATAPFYTR--THDVEIEE 121 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELL----DGILDKIPTFQGLKFSDTDLLDF 182 +++ AAAP LP + Y+IP + LL DG+L G + L++ Sbjct: 122 HFRKIHAAAPELPLFAYNIPVSVHSNLNPVMLLTLAKDGVLAGTKDSSGNDGAIRSLIEA 181 Query: 183 GQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAV 216 D +QF L G + + A + GA G V Sbjct: 182 RD--DAGLTEQFKILTGSETTVDFAYLAGADGVV 213 >4NQ1-A nrPDB Length = 290 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 72/299 (24%), Positives = 129/299 (43%), Gaps = 14/299 (4%) Query: 10 GLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEE 69 G + A +TPM N ++ + + V++ + +G + GTTGE +LS SE+ V + Sbjct: 4 GSIVALVTPM-RNDSVDVHHLRELVEFHIA-KGTHALVAAGTTGEAGTLSHSEKLLVIKT 61 Query: 70 WVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLK 129 + + K+++ VI + K+ EL Q A E GA ++ P ++KP + + +++ Sbjct: 62 VIEQAKERVP-VIAGTAMNATKDCIELTQQAMEYGAHAALIMTPAYIKPTQEGLYLHYSH 120 Query: 130 EVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQN 189 A + A+P Y++P T + E + L KI G+K + + Q + + Sbjct: 121 --IAQSVAIPIILYNVPGRTACDMLPETV--ARLAKISNIIGIKEATGQMTRLQQ-ILRL 175 Query: 190 RQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS--LALNYQF 247 + G D L+ GA G + T N K +M + D + L + Q Sbjct: 176 CEGSIDVYSGDDLTAAQWLLSGAKGVISVTANVAAKLMAKMCDLAMDDDQAGCLRIQEQL 235 Query: 248 CIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 + FV V M L+ G RLP+ + S + + E LK+L+ + Sbjct: 236 MPLHELLFVESNPIPVKWAMKKMGLIG----GELRLPMTELSEKHHQALEKVLKNLELI 290 >4XKY-B nrPDB Length = 300 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 103/215 (47%), Gaps = 7/215 (3%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 L G++ +TP+ ++ ++ + + +++L+ GV +FV GTTGE SLS R ++ Sbjct: 5 LSGIIPPLVTPLLDDDVLDVEGLQRLIEHLIA-GGVHALFVLGTTGESQSLSYKLRMEMI 63 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + K +L V++ + S+ ES LA AA+ GAD + P++ + LI F Sbjct: 64 KNTCRIAKGRL-PVLVCISDTSIVESVNLACLAADHGADAVVSAPPYYFATGQPE-LIEF 121 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + + LP + Y++P T V A + I + P G K S + + F + Sbjct: 122 YEHLLPQL-PLPLFLYNMPTHTKVNF-APATIQRIAEN-PGVIGFKDSSANTVYFQSVMY 178 Query: 188 QNRQQ-QFAFLFGVDEQLLSALVMGATGAVGSTYN 221 + F+ L G +E + ++++GA G V N Sbjct: 179 AMKDNPDFSMLVGPEEIMAESVLLGAHGGVNGGAN 213 >5UI3-D nrPDB Length = 341 Score = 57.8 bits (138), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 68/296 (22%), Positives = 118/296 (39%), Gaps = 38/296 (12%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 KKL+ L+ A TP NG+ + V + + E GV+ + V GTTGEG +S E Sbjct: 41 KKLR-LITAIKTPYLANGKFDLPAYDALVSHQI-ENGVEGLIVGGTTGEGHLMSWDEHVM 98 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + V DK VI + G+ S +E+ + +G I P++ K +K L+ Sbjct: 99 LIAHTVNAFGDK-TAVIGNTGSNSTREALHATEQGFAVGMHASLQINPYYGKT-SKAGLL 156 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 N V PA+ Y++P TG +++ D ++ +I ++ L +C Sbjct: 157 NHFNAVLNEGPAV---VYNVPGRTG-----QDIPDDVVMEI-------CQHSNFLGMKEC 201 Query: 186 VDQNRQQQF------AFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFE---- 235 +R + + + DE + GA G + T N + ++++ Sbjct: 202 TGNSRIKNYTSKGVNCWSGNDDESHDARHSNGAVGVISVTSNVIPGLMHKLMHGSPDPQL 261 Query: 236 QKDFSLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASRE 291 D + + FC I+ L + + L P +PL +A RE Sbjct: 262 NADLKELMAWMFCEPNPISLNTALAM-CGLARPVFRL--------PYVPLSRAQRE 308 >3D0C-A nrPDB Length = 314 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 58/235 (24%), Positives = 106/235 (45%), Gaps = 16/235 (6%) Query: 6 KKLQGLVAATITPMTE-NGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K+ + I P E EI++ + V++L+ + G++ I NG TGE +L++ E + Sbjct: 10 KRFSTISGINIVPFLEGTREIDWKGLDDNVEFLL-QNGIEVIVPNGNTGEFYALTIEEAK 68 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDI- 123 QVA VT+ + V+ +G S+ + EL + A + GAD + + P + P+ D Sbjct: 69 QVATR-VTELVNGRATVVAGIG-YSVDTAIELGKSAIDSGADCVMIHQP--VHPYITDAG 124 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 + + + + A A Y+ L+ I+ LD ++ G+K++ D+ Sbjct: 125 AVEYYRNIIEALDAPSIIYFKDAHLSDDVIKELAPLDKLV-------GIKYAINDIQRVT 177 Query: 184 QCVDQ-NRQQQFAFLFGVDEQLLSALVM-GATGAVGSTYNYLGKKTNQMLEAFEQ 236 Q + + AF+ G E+ GA G N +K+ +LEA E+ Sbjct: 178 QVMRAVPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEE 232 >3TUU-A nrPDB Length = 346 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 58/240 (24%), Positives = 101/240 (42%), Gaps = 32/240 (13%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQ---GVKNIFVNGTTGEGLSLSVSERRQVA 67 L+ A TP +G + + D LV Q G + + V GTTGEG +S E + Sbjct: 49 LITAIKTPYLPDGRFDL----EAYDALVNMQIVDGAEGVIVGGTTGEGQLMSWDEHIMLI 104 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 V + +VI + G+ S +E+ + +G I P++ K + ++ +F Sbjct: 105 GHTVNCFGGSI-KVIGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSLEGLVSHF 163 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + P P Y++P+ TG +++ G++ + +L +CV Sbjct: 164 ----ESVLPMGPTVIYNVPSRTG-----QDIPPGVIHTVA-------QSANLAGVKECVG 207 Query: 188 QNRQQQFA-----FLFGVDEQLLSA-LVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSL 241 +R +Q+ G D+Q A GATG + T N + Q+L F+ K+ SL Sbjct: 208 NDRIKQYTDNRIVVWSGNDDQCHDAKWDYGATGVISVTSNLIPGLMRQLL--FKGKNPSL 265 >4DPQ-A nrPDB Length = 360 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 53/237 (22%), Positives = 97/237 (40%), Gaps = 26/237 (10%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 ++ A TP +G + V+ + + G + + V GTTGEG +S E + Sbjct: 63 VITAIKTPYLPDGRFDLEAYDDLVNIQI-QNGAEGVIVGGTTGEGQLMSWDEHIMLIGHT 121 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 V + +VI + G+ S +E+ + +G I P++ K + ++ +F + Sbjct: 122 VNCFGGSI-KVIGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSIEGLIAHF-QS 179 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 V P + Y++P TG I + L + P G+K +CV R Sbjct: 180 VLHMGPTI---IYNVPGRTGQDIPPRAIFK--LSQNPNLAGVK----------ECVGNKR 224 Query: 191 QQQFA------FLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSL 241 +++ + DE S GATG + T N + +++ FE ++ SL Sbjct: 225 VEEYTENGVVVWSGNDDECHDSRWDYGATGVISVTSNLVPGLMRKLM--FEGRNSSL 279 >2HMC-A nrPDB Length = 344 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/237 (23%), Positives = 98/237 (41%), Gaps = 29/237 (12%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 G++ A +TP ++ +F + + L+ + G+ + G+ G+ L+ +R + Sbjct: 27 FSGVIPALMTPCRQDRTPDFDALVRKGKELIAD-GMSAVVYCGSMGDWPLLTDEQRMEGV 85 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 E V G VI+ GA++ + A HA ++GA G+ VI + Sbjct: 86 ERLVKAGI----PVIVGTGAVNTASAVAHAVHAQKVGAKGLMVIPRVLSRGSVIAAQKAH 141 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL---DFGQ 184 K + +AAP +P Y+ P G RA+ F L+ +L+ +FG Sbjct: 142 FKAILSAAPEIPAVIYNSP-YYGFATRAD-----------LFFALRAEHKNLVGFKEFGG 189 Query: 185 CVDQ--------NRQQQFAFLFGVDEQLLSALV-MGATGAVGSTYNYLGKKTNQMLE 232 D +R + + GVD ++ V GATGA+ N L K+ + + Sbjct: 190 PADMRYAAENITSRDDEVTLMIGVDTAVVHGFVNCGATGAITGIGNVLPKEVIHLCK 246 >4DVY-P nrPDB Length = 876 Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust. Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 16/145 (11%) Query: 77 KLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPF-FLKPWTKDILINFLKEVAAAA 135 + DQ + V SLKE QE ++ G D + + F F K + D+ KE Sbjct: 182 RTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFIFNKKQSSDV-----KEAINQE 236 Query: 136 PALPFYYYHIPALT----GVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNRQ 191 P +P I T G+ A +L LD+ F D ++LD D + Sbjct: 237 P-VPHVQPDIATTTTDIQGLPPEARDL----LDERGNFSKFTMGDMEMLDVEGVADIDPN 291 Query: 192 QQFAFLFGVDEQLLSALVMGATGAV 216 +F L + LS+++MG+ + Sbjct: 292 YKFNQLL-IHNNALSSVLMGSHNGI 315 >4UR8-A nrPDB Length = 311 Score = 31.6 bits (70), Expect = 0.51, Method: Compositional matrix adjust. Identities = 64/291 (21%), Positives = 118/291 (40%), Gaps = 23/291 (7%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 GL++ +T G ++V++L + +F G TGE SL E + Sbjct: 12 SGLLSFPVTHFDAEGRFAADSYREHVEWLAGYK-APVLFAAGGTGEFFSLKPDEIPTI-- 68 Query: 69 EWVTKGKDKLDQVIIHVGALSLKE-SQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 V K+ + I G E + ++A+ ++GADGI ++ P +L ++ L Sbjct: 69 --VAAAKEVAGETAIVSGCGYGTEIAVDIARSVEKVGADGI-LLLPHYLIDAPQEGLYAH 125 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 +K+V + Y ++ ++A+ L + D+ P G K D+ Q + Sbjct: 126 IKKVCQSVGIGVMVYNRDNSV----LQADTLAR-LCDECPNLVGFKDGTGDIGLVRQ-IT 179 Query: 188 QNRQQQFAFLFGV-DEQLLSALVMGA--TGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 + +L G+ +L + +GA T + +N++ N+ A + A Sbjct: 180 AKMGDRLMYLGGMPTAELFAEAYLGAGFTTYSSAVFNFVPGLANEFYAALRAGE--RATC 237 Query: 245 YQFCIQRFINFVV----KLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASRE 291 + + F F+ G+ VS KA + L G GP R PL+ + E Sbjct: 238 ERILVDFFYPFMAIRNRAKGYAVSAVKAGVRL-QGFNAGPVRAPLKDLTNE 287 >5CM5-A nrPDB Length = 277 Score = 30.8 bits (68), Expect = 0.74, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 11/89 (12%) Query: 43 VKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQE---LAQH 99 VKN NG G S ++SE + AEE+ + ++I++G L+ + Q+ +AQ Sbjct: 22 VKNFTANGLLSIGASPAMSEAPEEAEEFYKVAQ----ALLINIGTLTAQNEQDIIAIAQT 77 Query: 100 AAEIGA----DGIAVIAPFFLKPWTKDIL 124 A E G D +AV A + K + K +L Sbjct: 78 ANEAGLPIVFDPVAVGASTYRKQFCKLLL 106 >2FD5-A nrPDB Length = 180 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 16/29 (55%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 209 VMGATG-AVGSTYNYLGKKTNQMLEAFEQ 236 VMGA G VG Y + K MLEAFEQ Sbjct: 33 VMGAAGLTVGGFYAHFQSKDALMLEAFEQ 61 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6ARH-A nrPDB 387 e-108 2EHH-A nrPDB 309 9e-85 3PUD-A nrPDB 305 1e-83 5KTL-A nrPDB 304 3e-83 2YXG-A nrPDB 304 4e-83 6MQH-A nrPDB 299 1e-81 3FLU-A nrPDB 297 5e-81 3IRD-A nrPDB 294 3e-80 4NQ1-A nrPDB 293 7e-80 4PFM-A nrPDB 293 1e-79 2VC6-A nrPDB 292 1e-79 1XKY-A nrPDB 291 2e-79 5UD6-A nrPDB 291 3e-79 3G0S-A nrPDB 291 3e-79 4WOQ-A nrPDB 289 1e-78 1F73-A nrPDB 288 2e-78 6NVA-A nrPDB 288 2e-78 4I7U-A nrPDB 287 3e-78 3PS7-A nrPDB 287 5e-78 4MLJ-A nrPDB 283 5e-77 4IMD-A nrPDB 283 6e-77 3PB0-A nrPDB 283 7e-77 2RFG-A nrPDB 280 9e-76 5ZKA-A nrPDB 278 3e-75 5J5D-A nrPDB 274 4e-74 5LKY-A nrPDB 271 4e-73 4FHA-A nrPDB 269 1e-72 5AFD-A nrPDB 269 2e-72 3S5N-A nrPDB 264 4e-71 3LCG-A nrPDB 263 6e-71 4N4Q-A nrPDB 259 1e-69 3CPR-A nrPDB 259 2e-69 3SI9-A nrPDB 258 4e-69 3NA8-A nrPDB 245 2e-65 3DI0-A nrPDB 243 9e-65 1W37-A nrPDB 239 1e-63 4PTN-A nrPDB 234 4e-62 3N2X-A nrPDB 233 1e-61 2NUX-A nrPDB 231 4e-61 5UI3-D nrPDB 225 2e-59 2R91-A nrPDB 224 3e-59 4DPQ-A nrPDB 221 4e-58 3TUU-A nrPDB 218 3e-57 4UXD-A nrPDB 207 6e-54 4XKY-B nrPDB 206 1e-53 5C54-A nrPDB 193 8e-50 3D0C-A nrPDB 183 1e-46 2HMC-A nrPDB 174 6e-44 Sequences not found previously or not previously below threshold: 3E96-A nrPDB 157 6e-39 4UR8-A nrPDB 130 8e-31 3FKK-A nrPDB 110 7e-25 6DAO-B nrPDB 101 4e-22 4OQY-A nrPDB 35 0.038 6EQN-B nrPDB 34 0.067 4FQ5-B nrPDB 33 0.23 2ZVI-A nrPDB 32 0.29 1M1B-A nrPDB 32 0.32 4ZM6-A nrPDB 31 0.56 1YIX-A nrPDB 31 0.56 3L5A-A nrPDB 31 0.69 2LM5-A nrPDB 31 0.71 1DGU-A nrPDB 31 0.71 1XZP-A nrPDB 30 1.0 3S5S-A nrPDB 30 1.3 1NMO-A nrPDB 30 1.3 3R12-A nrPDB 30 1.7 3KT6-A nrPDB 29 2.2 1TYG-A nrPDB 29 2.2 1PN3-A nrPDB 29 2.6 4HWF-A nrPDB 29 2.7 3ZIU-A nrPDB 29 2.8 3H4T-A nrPDB 29 2.8 1OYR-A nrPDB 29 2.9 4CAZ-A nrPDB 29 3.4 1M3S-A nrPDB 29 3.4 2ABQ-A nrPDB 29 3.5 6G72-D nrPDB 29 3.5 3QN3-A nrPDB 28 4.6 4GX0-A nrPDB 28 4.7 4GVL-A nrPDB 28 5.0 4KB5-A nrPDB 28 5.1 3I9V-3 nrPDB 28 5.3 2ZHG-A nrPDB 28 5.8 2CZE-A nrPDB 28 6.0 4QDI-A nrPDB 28 6.1 5UJU-A nrPDB 28 6.4 2FSI-A nrPDB 27 8.0 >6ARH-A nrPDB Length = 338 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 320/320 (100%), Positives = 320/320 (100%) Query: 1 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 60 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV Sbjct: 19 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 78 Query: 61 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 120 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT Sbjct: 79 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 138 Query: 121 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 180 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL Sbjct: 139 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 198 Query: 181 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 240 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS Sbjct: 199 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 258 Query: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL Sbjct: 259 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 318 Query: 301 KSLDFLSFTDLKDGNLEAGS 320 KSLDFLSFTDLKDGNLEAGS Sbjct: 319 KSLDFLSFTDLKDGNLEAGS 338 >2EHH-A nrPDB Length = 294 Score = 309 bits (792), Expect = 9e-85, Method: Composition-based stats. Identities = 75/301 (24%), Positives = 135/301 (44%), Gaps = 13/301 (4%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 QG + A ITP E GE+++ +G +++ V + G I V GTTGE +L+ E +V Sbjct: 1 MFQGSIVALITPFKE-GEVDYEALGNLIEFHV-DNGTDAILVCGTTGESPTLTFEEHEKV 58 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 E V + ++ +VI G + E+ L HA E+GADG V+ P++ KP + + + Sbjct: 59 IEFAVKRAAGRI-KVIAGTGGNATHEAVHLTAHAKEVGADGALVVVPYYNKPTQRGLYEH 117 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F + A +P Y+IP+ T V+I + + + + K S ++ + V Sbjct: 118 F--KTVAQEVDIPIIIYNIPSRTCVEISVDTMFK-LASECENIVASKESTPNMDRISEIV 174 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + + F+ L G D L + +GA G + N + ++ +++ A + DF A Sbjct: 175 KR-LGESFSVLSGDDSLTLPMMALGAKGVISVANNVMPREVKELIRAALEGDFRRAREIH 233 Query: 247 FCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + + + F+ V ++ + RLPL + S E + LK + Sbjct: 234 YYLHDLFKVLFIETNPIPVKTACWMLGMCEK----EFRLPLTEMSPENENKLREVLKKYN 289 Query: 305 F 305 Sbjct: 290 L 290 >3PUD-A nrPDB Length = 291 Score = 305 bits (782), Expect = 1e-83, Method: Composition-based stats. Identities = 82/301 (27%), Positives = 140/301 (46%), Gaps = 13/301 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 +QG + A +TPM ++G +++ + + V++ + EQG +I GTTGE +LS+ E QV Sbjct: 2 IQGSIVAIVTPMLKDGGVDWKSLEKLVEWHI-EQGTNSIVAVGTTGEASTLSMEEHTQVI 60 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 +E + +K +I GA S +E+ EL + A ++GAD ++ P++ KP + + ++ Sbjct: 61 KEIIR-VANKRIPIIAGTGANSTREAIELTKAAKDLGADAALLVTPYYNKPTQEGLYQHY 119 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + A A LP Y++P TGV + + + L +IP G+K + D+ +D Sbjct: 120 --KAIAEAVELPLILYNVPGRTGVDLSNDTAVR--LAEIPNIVGIKDATGDVPRGKALID 175 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA--LNY 245 + A G DE +++GA G + T N K +++ KD A LN Sbjct: 176 -ALNGKMAVYSGDDETAWELMLLGADGNISVTANIAPKAMSEVCAVAIAKDEQQAKTLNN 234 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDF 305 + I F V M L I G RLPL + ++ + LK Sbjct: 235 KIANLHNILFCESNPIPVKWALHEMGL---IDTG-IRLPLTPLAEQYREPLRNALKDAGI 290 Query: 306 L 306 + Sbjct: 291 I 291 >5KTL-A nrPDB Length = 330 Score = 304 bits (779), Expect = 3e-83, Method: Composition-based stats. Identities = 81/302 (26%), Positives = 138/302 (45%), Gaps = 12/302 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 ++ A ITP +G +N++V + +LV + G + V GTTGE +LS E + Sbjct: 39 DFGTVLTAMITPFKADGSVNYAVAAELAAHLV-DNGTDTLVVCGTTGESPTLSWDEEYNL 97 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 E + K +VI G+ S KE+ Q AA+IG G + P++ KP + + Sbjct: 98 FVEVLQTVAGK-AKVIAGCGSNSTKEAIAATQKAAKIGVHGTLQVVPYYNKPPQAGLYQH 156 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F + +A A P LP Y++P TG + E ++ L +I G+K + +L G+ + Sbjct: 157 F-QAIAQACPDLPLLLYNVPGRTGQNLSPETVVR--LAEIDNIIGVKEASGNLDQAGE-I 212 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 ++ ++F G D L L +GA G V + +G + QM++AF ++A + Sbjct: 213 RRSTPKEFQIYAGDDSLTLPLLAIGAKGVVSVASHLVGNQLQQMIQAFNSGQVTVASDIH 272 Query: 247 FCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + F+ + Q + G +G R PL A E + EA +K L+ Sbjct: 273 LRLLPLFKALFITTNPIPIKQALKL----QGWEVGSTRPPLSDADAEVSQKLEAVMKHLN 328 Query: 305 FL 306 + Sbjct: 329 LI 330 >2YXG-A nrPDB Length = 289 Score = 304 bits (778), Expect = 4e-83, Method: Composition-based stats. Identities = 79/302 (26%), Positives = 140/302 (46%), Gaps = 15/302 (4%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +G+ A ITP +N E++F + + +++L+ E GV I GTTGE +LS E ++V Sbjct: 1 MFKGVYPAIITPF-KNKEVDFDGLEENINFLI-ENGVSGIVAVGTTGESPTLSHEEHKKV 58 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 E+ V ++ QVI G+ +E+ EL+ A ++GAD + I P++ KP + + + Sbjct: 59 IEKVVDVVNGRV-QVIAGAGSNCTEEAIELSVFAEDVGADAVLSITPYYNKPTQEGLRKH 117 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F K A + LP Y++P+ T V + + + + ++ +K ++ +L + + Sbjct: 118 FGK--VAESINLPIVLYNVPSRTAVNLEPKTV-KLLAEEYSNISAVKEANPNLSQVSELI 174 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + L G DE L + +G G + N + K+ +M+ + DF A Sbjct: 175 H---DAKITVLSGNDELTLPIIALGGKGVISVVANIVPKEFVEMVNYALEGDFEKAREIH 231 Query: 247 FCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + + + F+ V +M G P G RLPL + S E E LK L Sbjct: 232 YKLFPLMKAMFIETNPIPVKTALNMM----GRPAGELRLPLCEMSEEHKKILENVLKDLG 287 Query: 305 FL 306 + Sbjct: 288 LI 289 >6MQH-A nrPDB Length = 308 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 72/302 (23%), Positives = 129/302 (42%), Gaps = 13/302 (4%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +++G V A +TPM E+G ++ + + +D+ ++E G + V GT+GE +LSV E + Sbjct: 18 QIRGSVPAIVTPMLEDGGLDLAAFRKLIDWHIEE-GTDALVVVGTSGESATLSVDEHVLM 76 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 E V ++ ++ G S E+ EL++HA +GAD + P++ KP + I + Sbjct: 77 IETAVKHAAKRI-PIVAGAGGNSTTEAIELSKHAKAVGADATLQVVPYYNKPTQEGIYRH 135 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F + A A LP Y++P T + E L L ++P G+K + ++ Q + Sbjct: 136 F--KAIAEAVDLPVILYNVPGRTVADMSNETTLR--LAQVPGIIGVKDATGNIDRAAQLI 191 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F+ G D ++ +++G G + T N + +++ A D A Sbjct: 192 -KAAPAHFSIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAALAADVKTAREIH 250 Query: 247 --FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 F+ V M G G RLPL ++ L+ Sbjct: 251 MKLLSLHKHLFIEANPIPVKWALQQM----GKIAGGIRLPLTPLDERCHETVRGALREAG 306 Query: 305 FL 306 L Sbjct: 307 LL 308 >3FLU-A nrPDB Length = 297 Score = 297 bits (760), Expect = 5e-81, Method: Composition-based stats. Identities = 83/303 (27%), Positives = 131/303 (43%), Gaps = 9/303 (2%) Query: 4 PKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER 63 P LQG + A ITPM ++G I++ + +D+ + E G I GTTGE +LSV E Sbjct: 4 PFTMLQGSLVALITPMNQDGSIHYEQLRDLIDWHI-ENGTDGIVAVGTTGESATLSVEEH 62 Query: 64 RQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDI 123 V E V K VI GA + E+ L+Q A + GAD + P++ KP + I Sbjct: 63 TAVIEAVVK-HVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGI 121 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 +F + A A ++P Y++P T V + + +L L +IP G+K + ++ Sbjct: 122 YQHF--KTIAEATSIPMIIYNVPGRTVVSMTNDTILR--LAEIPNIVGVKEASGNIGSNI 177 Query: 184 QCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243 + +++ + F L G D L ++ G G + N K M A Q D +LA Sbjct: 178 ELINRA-PEGFVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMCRAALQGDIALAR 236 Query: 244 NYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + + + + A+ L G RLPL + A LK+ Sbjct: 237 ELNDRLIPIYDTMFCEPSPAAPKWAVSAL--GRCEPHVRLPLVPLTENGQAKVRAALKAS 294 Query: 304 DFL 306 L Sbjct: 295 GQL 297 >3IRD-A nrPDB Length = 291 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 69/301 (22%), Positives = 134/301 (44%), Gaps = 14/301 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 +G A ITP T G ++F + + +++ +K + I V GTTGE +++ +ER++ Sbjct: 3 FKGSGVAIITPFTNTG-VDFDKLSELIEWHIKSK-TDAIIVCGTTGEATTMTETERKETI 60 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + +V +K VI G+ + S +++ A IG DG+ VI P++ K K ++ +F Sbjct: 61 K-FVIDKVNKRIPVIAGTGSNNTAASIAMSKWAESIGVDGLLVITPYYNKTTQKGLVKHF 119 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + + A + P Y++P TG+ I L L + +K + ++ Q + Sbjct: 120 --KAVSDAVSTPIIIYNVPGRTGLNITPGTL--KELCEDKNIVAVKEASGNISQIAQ-IK 174 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQF 247 + G D+Q++ L +G G + N + + + M E + + AL Q Sbjct: 175 ALCGDKLDIYSGNDDQIIPILALGGIGVISVLANVIPEDVHNMCELYLNGKVNEALKIQL 234 Query: 248 CIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDF 305 N F+ V +M + +G RLPL + + + + +LK+ + Sbjct: 235 DSLALTNALFIETNPIPVKTAMNLMNM----KVGDLRLPLCEMNENNLEILKKELKAYNL 290 Query: 306 L 306 + Sbjct: 291 M 291 >4NQ1-A nrPDB Length = 290 Score = 293 bits (750), Expect = 7e-80, Method: Composition-based stats. Identities = 71/302 (23%), Positives = 129/302 (42%), Gaps = 14/302 (4%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 G + A +TPM + ++ + + V++ + +G + GTTGE +LS SE+ V Sbjct: 1 MFSGSIVALVTPMRND-SVDVHHLRELVEFHIA-KGTHALVAAGTTGEAGTLSHSEKLLV 58 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + + + K+++ VI + K+ EL Q A E GA ++ P ++KP + + ++ Sbjct: 59 IKTVIEQAKERV-PVIAGTAMNATKDCIELTQQAMEYGAHAALIMTPAYIKPTQEGLYLH 117 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 + A + A+P Y++P T + E + L KI G+K + + Q + Sbjct: 118 YSH--IAQSVAIPIILYNVPGRTACDMLPETVAR--LAKISNIIGIKEATGQMTRLQQIL 173 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + + G D L+ GA G + T N K +M + D + L Q Sbjct: 174 -RLCEGSIDVYSGDDLTAAQWLLSGAKGVISVTANVAAKLMAKMCDLAMDDDQAGCLRIQ 232 Query: 247 FCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + + FV V M L+ G RLP+ + S + + E LK+L+ Sbjct: 233 EQLMPLHELLFVESNPIPVKWAMKKMGLIG----GELRLPMTELSEKHHQALEKVLKNLE 288 Query: 305 FL 306 + Sbjct: 289 LI 290 >4PFM-A nrPDB Length = 295 Score = 293 bits (749), Expect = 1e-79, Method: Composition-based stats. Identities = 74/302 (24%), Positives = 128/302 (42%), Gaps = 12/302 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 + G + A ITP+ +G ++++ + + V+Y + E G I GTTGE +L +SE Sbjct: 1 HMINGSIVALITPLNSDGTVDYTSLEKLVEYHITE-GTDAIVAVGTTGESATLPISEHIA 59 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 V + V ++ VI GA + E+ EL + ++G + + P++ KP K ++ Sbjct: 60 VVGQTVKFASGRI-PVIGGNGANATAEAIELTKAQNKLGVAAMLGVTPYYNKPSPKGLIA 118 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 ++ AA+ +P Y++P T V + E + L ++P G+K + D+ Q Sbjct: 119 HY--TAVAASTDIPQILYNVPGRTAVDMLPETIAQ--LVEVPNIIGVKDATGDVARVKQ- 173 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + F G D L +G G + N + K M +A D A+ Sbjct: 174 LRDLCGNDFLLYSGDDATAREFLTLGGDGVISVANNIVPKLFKLMCDAALAGDTQAAMAA 233 Query: 246 QFCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + I+ + F V M L+S G RLPL + S EF +K+ Sbjct: 234 EDQIKGLFSALFCEANPIPVKWAAHKMGLIS---QGDIRLPLTELSTEFHGLLLDAMKNA 290 Query: 304 DF 305 Sbjct: 291 RI 292 >2VC6-A nrPDB Length = 292 Score = 292 bits (747), Expect = 1e-79, Method: Composition-based stats. Identities = 76/302 (25%), Positives = 126/302 (41%), Gaps = 13/302 (4%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +G + A +TP + I+ + V++ ++E G + GTTGE +LS SE QV Sbjct: 1 MFEGSITALVTPF-ADDRIDEVALHDLVEWQIEE-GSFGLVPCGTTGESPTLSKSEHEQV 58 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 E + ++ VI G+ S E+ +HA GADG+ +++P++ KP + I + Sbjct: 59 VEITIKTANGRV-PVIAGAGSNSTAEAIAFVRHAQNAGADGVLIVSPYYNKPTQEGIYQH 117 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F + AA +P Y+IP + ++I E L I + P +G+K + +LL Sbjct: 118 F--KAIDAASTIPIIVYNIPGRSAIEIHVETLAR-IFEDCPNVKGVKDATGNLLR-PSLE 173 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F L G D L + G G + T N +A DF+ AL Q Sbjct: 174 RMACGEDFNLLTGEDGTALGYMAHGGHGCISVTANVAPALCADFQQACLNGDFAAALKLQ 233 Query: 247 FCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + F+ G + + G RLPL S F + + ++ Sbjct: 234 DRLMPLHRALFLETNPAGAKYALQRLGRMR----GDLRLPLVTISPSFQEEIDDAMRHAG 289 Query: 305 FL 306 L Sbjct: 290 IL 291 >1XKY-A nrPDB Length = 301 Score = 291 bits (745), Expect = 2e-79, Method: Composition-based stats. Identities = 76/297 (25%), Positives = 143/297 (48%), Gaps = 9/297 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 + A +TP NG I+F+ + V+YL+ + G I V GTTGE +L+ E+ + Sbjct: 12 DFGTIATAMVTPFDINGNIDFAKTTKLVNYLI-DNGTTAIVVGGTTGESPTLTSEEKVAL 70 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 V+ DK VI G+ + S +L + A E+G D + ++AP++ KP + + + Sbjct: 71 YRHVVS-VVDKRVPVIAGTGSNNTHASIDLTKKATEVGVDAVMLVAPYYNKPSQEGMYQH 129 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F + A + LP Y++P + V+I + ++ L +I +K + D+L + + Sbjct: 130 F--KAIAESTPLPVMLYNVPGRSIVQISVDTVVR--LSEIENIVAIKDAGGDVLTMTEII 185 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 ++ FA G D L A+ +GA G V + +G + +M+ AF+ +F A Sbjct: 186 EKTAD-DFAVYSGDDGLTLPAMAVGAKGIVSVASHVIGNEMQEMIAAFQAGEFKKAQKLH 244 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + R + + + K + +V G+ +G RLPL + E + ++ ++S+ Sbjct: 245 QLLVRVTDSLFMAPSP-TPVKTALQMV-GLDVGSVRLPLLPLTEEERVTLQSVMQSI 299 >5UD6-A nrPDB Length = 327 Score = 291 bits (745), Expect = 3e-79, Method: Composition-based stats. Identities = 81/306 (26%), Positives = 137/306 (44%), Gaps = 8/306 (2%) Query: 4 PKKKLQGLVAATITPMTENG-EINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSE 62 PK ++ A +TP G E+++ V +L E G I V GTTGE +L+ SE Sbjct: 24 PKHFFGRVITALVTPFKLTGVEVDYGVAESLAAHL-AENGSDAIIVAGTTGESATLTWSE 82 Query: 63 RRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKD 122 ++ + +VI G+ S +E+ E + +A++G DG + P++ KP + Sbjct: 83 EYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQG 142 Query: 123 ILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDF 182 I+ +F + +A AAP LP Y+IP TG+ + AE + + + P LK + +L F Sbjct: 143 IMAHF-RAIANAAPDLPMMLYNIPGRTGINMTAETSIK-LAEMCPNIVALKEASGNLEQF 200 Query: 183 GQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQ-KDFSL 241 + + + FA G D L L +G G V +++G + +M+E F + Sbjct: 201 AR-IRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEE 259 Query: 242 ALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLK 301 A + + + KA + L+ G P+GP RLPL + + Sbjct: 260 AFRIHCRYMDLFEALFVMANPI-PAKAALRLL-GWPVGPTRLPLTDITASAEQQLRQAMI 317 Query: 302 SLDFLS 307 + LS Sbjct: 318 AAGLLS 323 >3G0S-A nrPDB Length = 316 Score = 291 bits (744), Expect = 3e-79, Method: Composition-based stats. Identities = 72/302 (23%), Positives = 120/302 (39%), Gaps = 12/302 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 G + A +TPM E G ++ S + + +DY V G I GTTGE +LS E V Sbjct: 25 MFTGSIVALVTPMDEKGNVSRSCLKKLIDYHVA-NGTSAIVSVGTTGESATLSHDEHGDV 83 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + ++ VI GA + E+ L Q + G G + P++ +P + + + Sbjct: 84 VMMTLELADGRI-PVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPTQEGLFQH 142 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F + A LP Y++P+ TG + E + G L +I +K + +L Q + Sbjct: 143 F--KAIAEHTDLPQILYNVPSRTGCDMLPETV--GRLAEIKNIIAIKEATGNLTRVHQ-I 197 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F L G D L + +G G + T N ++ M + + F+ A Sbjct: 198 KELVSDDFILLSGDDASALDFMQLGGHGVISVTANVAAREMADMCKLAAEGQFAEARAIN 257 Query: 247 FCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + N FV V + L + RLP+ + D +A L+ Sbjct: 258 QRLMPLHNKLFVEPNPIPVKWACKALGL---VATDTLRLPMTPITDHGRDIVKAALQHAG 314 Query: 305 FL 306 L Sbjct: 315 LL 316 >4WOQ-A nrPDB Length = 302 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 78/298 (26%), Positives = 145/298 (48%), Gaps = 9/298 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 ++G+ +A + + G IN + Q + + + V ++V G+TGE LS E+++ Sbjct: 13 TDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGSTGENFMLSTDEKKR 72 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + E + K+++ ++I VG+++LKE+ ELA+ ++G D I+ + PF+ K ++ + Sbjct: 73 IFEIAKDEVKEEI-KLIAQVGSVNLKEAVELAKFTTDLGYDAISAVTPFYYKFDFEE-IK 130 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 ++ + + Y IP LTGV + ++ G L + G+KF+ D + Sbjct: 131 HYYNTIINSVDNR-LIIYSIPFLTGVDMSLDQF--GELFENEKIIGVKFTAADFYLLERM 187 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + G DE +L A V+G GA+GST+N G + Q+ E + + S AL Sbjct: 188 --RKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFELTKNEKISEALEV 245 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 Q I + LG G+ QT ++ G+ G R P+++A+ E A+ + Sbjct: 246 QHVTNDLITDI--LGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEMKSRAKEIYRKY 301 >1F73-A nrPDB Length = 293 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 84/303 (27%), Positives = 146/303 (48%), Gaps = 12/303 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 + L+G+ +A + E+G IN + Q + + + + V ++V G+TGE LS E+++ Sbjct: 2 RDLKGIFSALLVSFNEDGTINEKGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTEEKKE 61 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + + KD++ +I VG+++LKE+ EL ++A E+G D ++ + PF+ K + + Sbjct: 62 IFRIAKDEAKDQIA-LIAQVGSVNLKEAVELGKYATELGYDCLSAVTPFYYKFSFPE-IK 119 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 ++ + A + Y IP LTGV + E+ G L K P G+KF+ D + Sbjct: 120 HYYDTIIAETGS-NMIVYSIPFLTGVNMGIEQF--GELYKNPKVLGVKFTAGDFYLLERL 176 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + G DE +L A +G GA+GST+N G + Q+ E + AL Sbjct: 177 --KKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTKAGKLKEALEI 234 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQ-KASREFTDSAEAKLKSLD 304 Q I ++ G ++ + + G+ G R P+ KA+ E A+AK Sbjct: 235 QHVTNDLIEGILANGLYLT--IKELLKLEGVDAGYCREPMTSKATAE--QVAKAKDLKAK 290 Query: 305 FLS 307 FLS Sbjct: 291 FLS 293 >6NVA-A nrPDB Length = 294 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 71/303 (23%), Positives = 119/303 (39%), Gaps = 12/303 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 G + A +TPM E G + + + + +DY V G I GTTGE +L+ E Sbjct: 2 HMFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVAS-GTSAIVSVGTTGESATLNHDEHAD 60 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 V + ++ VI GA + E+ L Q + G G + P++ +P + + Sbjct: 61 VVMMTLDLADGRI-PVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQ 119 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 +F + A LP Y++P+ TG + E + G L K+ G+ + +L Q Sbjct: 120 HF--KAIAEHTDLPQILYNVPSRTGCDLLPETV--GRLAKVKNIIGIXEATGNLTRVNQ- 174 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + + F L G D L + +G G + T N + QM + + F+ A Sbjct: 175 IKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVI 234 Query: 246 QFCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + N FV V + L + RLP+ + ++ A LK Sbjct: 235 NQRLMPLHNKLFVEPNPIPVKWACKELGL---VATDTLRLPMTPITDSGRETVRAALKHA 291 Query: 304 DFL 306 L Sbjct: 292 GLL 294 >4I7U-A nrPDB Length = 308 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 78/303 (25%), Positives = 129/303 (42%), Gaps = 9/303 (2%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 +K +G + A ITP T+NG ++ +V++ + E G + GTTGE +LS E + Sbjct: 13 EKMFKGSIPALITPFTDNGAVDEQAFAAHVEWQIAE-GSNGLVPVGTTGESPTLSHDEHK 71 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 +V E + + K VI G+ + E+ ELA HA + GAD + V+ P++ KP K + Sbjct: 72 RVVELCI-EVAAKRVPVIAGAGSNNTDEAIELALHAQDAGADALLVVTPYYNKPTQKGLF 130 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 +F A A LP Y+IP + V + E + ++ G+K + L + Sbjct: 131 AHF--SAVAEAVKLPIVIYNIPPRSVVDMSPETM-GALVKAHKNIVGVKDATGKLDRVSE 187 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 + + F L G D L G G + + N + ++ A D++ AL Sbjct: 188 Q-RISCGKDFIQLSGEDSTALGFNAHGGVGCISVSANVAPRLCSEFQAAMLAGDYAKALE 246 Query: 245 YQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQK-ASREFTDSAEAKLKSL 303 YQ + + GV TK ++ G R PL + +A LK Sbjct: 247 YQDRLMPLHRAIFMEP-GVCGTKYALSKTRGCNR-KVRSPLMSTLEPATEAAIDAALKHA 304 Query: 304 DFL 306 + Sbjct: 305 GLM 307 >3PS7-A nrPDB Length = 292 Score = 287 bits (734), Expect = 5e-78, Method: Composition-based stats. Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 13/303 (4%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 + G + A +TP G +++ + + VD+ +++ G I GTTGE +L V E QV Sbjct: 1 MIAGSMVALVTPFDAQGRLDWDSLAKLVDFHLQD-GTNAIVAVGTTGESATLDVEEHIQV 59 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 V + K ++ VI GA S +E+ L + A GAD ++ P++ KP + + + Sbjct: 60 VRRVVDQVKGRI-PVIAGTGANSTREAVALTEAAKSGGADACLLVTPYYNKPTQEGMYQH 118 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F A A A+P Y++P T + E + L K+P G+K + DL + + Sbjct: 119 FRH--IAEAVAIPQILYNVPGRTSCDMLPETVER--LSKVPNIIGIKEATGDLQRAKEVI 174 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 ++ + F G D + +++G G + T N + + + A + D + A Sbjct: 175 ER-VGKDFLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAAAARAIN 233 Query: 247 FCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 + F+ V M L IP G RLPL S D ++ Sbjct: 234 DRLMPLHKALFIESNPIPVKWALHEMGL---IPEG-IRLPLTWLSPHCHDPLRQAMRQTG 289 Query: 305 FLS 307 L+ Sbjct: 290 VLA 292 >4MLJ-A nrPDB Length = 306 Score = 283 bits (725), Expect = 5e-77, Method: Composition-based stats. Identities = 70/309 (22%), Positives = 124/309 (40%), Gaps = 12/309 (3%) Query: 2 AFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVS 61 + K + G + A ITP +NG+++ + + + E G+ + GTTGE +L+ Sbjct: 8 SMDKNIIIGAMTALITPF-KNGKVDEQSYARLIKRQI-ENGIDAVVPVGTTGESATLTHE 65 Query: 62 ERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTK 121 E R E V K +V+ G+ + E+ LA+ A E GADGI +APF+ KP + Sbjct: 66 EHRTCIEIAVETCKGTKVKVLAGAGSNATHEAVGLAKFAKEHGADGILSVAPFYNKPTQQ 125 Query: 122 DILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLD 181 + ++ + A + +P Y++P TG +I + ++ + G+K + ++ Sbjct: 126 GLYEHY--KAIAQSVDIPVLLYNVPGRTGCEISTDTIIK-LFRDCENIYGVKEASGNIDK 182 Query: 182 FGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSL 241 + + + + G D L G G + T N L + + +++ Sbjct: 183 CVDLL--AHEPRMMLISGEDAINYPILSNGGKGVISVTSNLLPDMISALTHFALDENYKE 240 Query: 242 ALNYQFCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAK 299 A + I F + M L I RLPL S+E E Sbjct: 241 AKKINDELYNINKILFCESNPIPIKTA---MYLAGLIESLEFRLPLCSPSKENFAKIEEV 297 Query: 300 LKSLDFLSF 308 +K F Sbjct: 298 MKKYKIKGF 306 >4IMD-A nrPDB Length = 293 Score = 283 bits (725), Expect = 6e-77, Method: Composition-based stats. Identities = 83/301 (27%), Positives = 141/301 (46%), Gaps = 11/301 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 K L+G+ +A + +G IN + Q V Y + + V ++V G+TGE LS E+++ Sbjct: 2 KNLKGIFSALLVSFNADGSINEKGLRQIVRYNIDKMKVDGLYVGGSTGENFMLSTEEKKE 61 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + + KD++ +I VG+++L+E+ EL ++A E+G D ++ + PF+ K + + Sbjct: 62 IFRIAKDEAKDEIA-LIAQVGSVNLQEAIELGKYATELGYDSLSAVTPFYYKFSFPE-IK 119 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 ++ + A Y IP LTGV I E+ G L K P G+KF+ D + Sbjct: 120 HYYDSIIEATGNY-MIVYSIPFLTGVNIGVEQF--GELYKNPKVLGVKFTAGDFYLLERL 176 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + G DE +L A +G GA+GST+N G + Q+ E + AL Sbjct: 177 --KKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTQAGKLKEALEI 234 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKA--SREFTDSAEAKLKSL 303 Q I ++ G ++ + + G+ G R P+ K S + + E K K L Sbjct: 235 QHVTNDLIEGILANGLYLT--IKELLKLDGVEAGYCREPMTKELSSEKVAFAKELKAKYL 292 Query: 304 D 304 Sbjct: 293 S 293 >3PB0-A nrPDB Length = 300 Score = 283 bits (724), Expect = 7e-77, Method: Composition-based stats. Identities = 69/307 (22%), Positives = 128/307 (41%), Gaps = 14/307 (4%) Query: 4 PKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER 63 P +G+ A +TP +NGE++ + V Y + E GV + V GTTGE +++ ER Sbjct: 4 PFTMFRGVGTAIVTPF-KNGELDLESYERLVRYQL-ENGVNALIVLGTTGESPTVNEDER 61 Query: 64 RQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDI 123 ++ + K+ VI+ G S +++ +L + A ++GA+G+ V+ P++ KP + + Sbjct: 62 EKLVSRTLEIVDGKI-PVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTPYYNKPTQEGL 120 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 ++ + + L Y++P TGV + E I + G+K ++ Sbjct: 121 YQHY--KYISERTDLGIVVYNVPGRTGVNVLPETAAR-IAADLKNVVGIKEANPAAAQID 177 Query: 184 QCVDQNRQ--QQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSL 241 + V +Q F G D++ L G G + N K+ ++ + + Sbjct: 178 RTVSLTKQARSDFMVWSGNDDRTFYLLCAGGDGVISVVSNVAPKQMVELCAEYFSGNLEK 237 Query: 242 ALNYQFCIQRFIN--FVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAK 299 + ++ + FV V +M G RLPL AS + + Sbjct: 238 SREVHRKLRPLMKALFVETNPIPVKAALNLM----GFIENELRLPLVPASEKTVELLRNV 293 Query: 300 LKSLDFL 306 LK L Sbjct: 294 LKESGLL 300 >2RFG-A nrPDB Length = 297 Score = 280 bits (715), Expect = 9e-76, Method: Composition-based stats. Identities = 72/297 (24%), Positives = 125/297 (42%), Gaps = 10/297 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +G + A ITP NG+++ + VD+ +K G + GTTGE +L+ E ++V Sbjct: 1 MFRGSLIAMITPFI-NGQVDEKALAGLVDWQIK-HGAHGLVPVGTTGESPTLTEEEHKRV 58 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + + ++ VI G+ + E+ AQHA + GAD + +A ++ +P + + + Sbjct: 59 VALVAEQAQGRV-PVIAGAGSNNPVEAVRYAQHAQQAGADAVLCVAGYYNRPSQEGLYQH 117 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F ++ A +P Y+IP V I+ E + L +P G+K + TDL + Sbjct: 118 F--KMVHDAIDIPIIVYNIPPRAVVDIKPETMAR--LAALPRIVGVKDATTDLARISRE- 172 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F+FL G D ++ G G + + N QM A Q DF AL Sbjct: 173 RMLINKPFSFLSGDDMTAIAYNASGGQGCISVSANIAPALYGQMQTATLQGDFREALRIH 232 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + + + A L G+ RLP+ S + + + L Sbjct: 233 DLLAPLHEALFREPSPAGAKYAASLL--GLCNEECRLPIVPLSEQTKSDIKNIINEL 287 >5ZKA-A nrPDB Length = 307 Score = 278 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 77/296 (26%), Positives = 141/296 (47%), Gaps = 9/296 (3%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 ++G+ +A + P E+G IN + + + Y + + V ++V G+TGE +S E+++V Sbjct: 18 MKGIYSALMVPYNEDGSINEKGLREIIRYNIDKMKVDGLYVGGSTGENFMISTEEKKRVF 77 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 E + + KD ++ +I VG+++L E+ EL ++ ++G ++ + PF+ K + + ++ Sbjct: 78 EIAIDEAKDSVN-LIAQVGSINLNEAVELGKYVTKLGYKCLSAVTPFYYKFDFSE-IKDY 135 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + + Y IP LTGV + + G L + G+KF+ D + Sbjct: 136 YETIVRETGNY-MIIYSIPFLTGVNMSLSQF--GELFENEKIIGVKFTAGDFYLLERV-- 190 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQF 247 + G DE LL A V+G GA+GSTYN G + Q+ E + AL Q Sbjct: 191 RKAFPDKLIFAGFDEMLLPATVLGVDGAIGSTYNINGIRAKQIFELAKNSKIDEALKIQH 250 Query: 248 CIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 I ++ G QT + + G+ G R P++K S++ + A+ K Sbjct: 251 TTNDLIEGILSNGL--YQTIKEILKLEGVDAGYCRKPMKKISQKQIEFAKELHKKF 304 >5J5D-A nrPDB Length = 300 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 84/300 (28%), Positives = 139/300 (46%), Gaps = 11/300 (3%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 +L L+ A +TP + +G ++ + + ++LV +QG + V+GTTGE + + E+ ++ Sbjct: 11 RLGTLLTAMVTPFSGDGSLDTATAARLANHLV-DQGCDGLVVSGTTGESPTTTDGEKIEL 69 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + D+ +VI G S LA+ A GA G+ V+ P++ KP + + + Sbjct: 70 LRAVLEAVGDR-ARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAH 128 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 F A A LP Y IP + V I + + L P G+K + DL Q + Sbjct: 129 F--TAVADATELPMLLYDIPGRSAVPIEPDTI--RALASHPNIVGVKDAKADLHSGAQIM 184 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 A+ G D L L MGATG + + + ++L AF D + A Sbjct: 185 ---ADTGLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKIN 241 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 + N + +LG GV+ +KA + L GI +G PRLP A+ E D+ A +++ L Sbjct: 242 IAVAPLCNAMSRLG-GVTLSKAGLRL-QGIDVGDPRLPQVAATPEQIDALAADMRAASVL 299 >5LKY-A nrPDB Length = 300 Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 80/300 (26%), Positives = 140/300 (46%), Gaps = 9/300 (3%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 K L+GL AA + P ENG++N + Q ++ + + ++VNG++GE L+ +++Q Sbjct: 10 KDLKGLYAALLVPFDENGQVNEQGLKQIAQNAIETEELDGLYVNGSSGENFLLNTEQKKQ 69 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 V + DK+ ++I VG+L L E+ EL ++A E+G D ++ + PF+ P+T + + Sbjct: 70 VFKVAKEAVGDKV-KLIAQVGSLDLNEAIELGKYATELGYDALSAVTPFYY-PFTFEEIR 127 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 ++ ++ A Y IP LTGV I E+ L G+K++ + + Sbjct: 128 DYYFDIIEATQN-NMIIYAIPDLTGVNISIEQF--SELFNHEKIVGVKYTAPNFFLLERI 184 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + L G DE L+ A + G GA+GSTYN G++ ++ + Q A Sbjct: 185 --RKAFPDKLILSGCDEMLVQATISGVDGAIGSTYNVNGRRARKIFDLARQGQIQEAYQL 242 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDF 305 Q I V L G+ T + GI G P+ P + + + + + D Sbjct: 243 QHDSNDIIETV--LSMGIYPTLKEILRHRGIDAGLPKRPFKPFNEAHRQTLDQLIAKYDL 300 >4FHA-A nrPDB Length = 311 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 77/300 (25%), Positives = 127/300 (42%), Gaps = 11/300 (3%) Query: 1 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 60 M++ K ++ A ITP E+G INF I +++L+ I + GTT E +L+ Sbjct: 1 MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHH-TDGILLAGTTAESPTLTH 59 Query: 61 SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIG-ADGIAVIAPFFLKPW 119 E ++ V K + +I VG ++S E + AE G I P++ KP Sbjct: 60 DEELELF-AAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPS 118 Query: 120 TKDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDL 179 + + +F + A A LP Y+IP V++ E +L L P G+K T L Sbjct: 119 QEGMYQHF--KAIADASDLPIIIYNIPGRVVVELTPETMLR--LADHPNIIGVKE-CTSL 173 Query: 180 LDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDF 239 + ++ ++ ++F G D A+ +GA G + + G + ++M A + D Sbjct: 174 ANMAYLIE-HKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFTAIAESDM 232 Query: 240 SLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAK 299 A Q +N + + KAI+ + G GP RLPL A E Sbjct: 233 KKAAAIQRKFIPKVNALFSYPSP-APVKAILNYM-GFEAGPTRLPLVPAPEEDVKRIIKV 290 >5AFD-A nrPDB Length = 300 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 120/301 (39%), Positives = 169/301 (56%), Gaps = 6/301 (1%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 KKL GL+AA TP + +NF I + +L+ + GVK I+V GTTGEG+ SV ER+ Sbjct: 2 KKLTGLIAAPHTPFDSSSNVNFEEIDKIAKHLIND-GVKGIYVCGTTGEGIHCSVEERKA 60 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 +AE WV+ KLD +I+H GALS+ ++ EL +HA + + I P F KP + L+ Sbjct: 61 IAERWVSACNHKLD-IIVHTGALSIVDTLELTRHADTLDILATSAIGPCFFKPGSVSDLV 119 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 + +AAAAP+ FYYYH ++GV + EE L +IP GLKF+ DL ++ +C Sbjct: 120 EYCATIAAAAPSKGFYYYH-SGMSGVNLNMEEFLIQADKRIPNLSGLKFNSGDLYEYQRC 178 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + + +F FGVDE L AL +GA AVGSTYNY N ++EAF + D N Sbjct: 179 L-RACDGKFDVPFGVDEFLPGALAVGAKSAVGSTYNYAAPHFNSIIEAFNKGDHDAVFNK 237 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDF 305 + I +V+ G GV+ K M L I G PRLPL S E + K+++ +F Sbjct: 238 MTNVIELIRVLVEFG-GVAAGKIAMEL-HDINAGDPRLPLMPLSAEQKLTVVEKMRAANF 295 Query: 306 L 306 L Sbjct: 296 L 296 >3S5N-A nrPDB Length = 304 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 81/304 (26%), Positives = 135/304 (44%), Gaps = 13/304 (4%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K + G+ TP T E+++ + + + + + + V G+ GE L+ SER Sbjct: 9 KVDIAGIYPPVTTPFTATAEVDYGKLEENL-HKLGTFPFRGFVVQGSNGEFPFLTSSERL 67 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLK-PWTKDI 123 +V V + K ++ G S + + E+ A++GAD V+ P + + + Sbjct: 68 EVVSR-VRQAMPKNRLLLAGSGCESTQATVEMTVSMAQVGADAAMVVTPCYYRGRMSSAA 126 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 LI+ +VA +P +P Y +PA TG+ + + ++ L + P G+K S D+ G Sbjct: 127 LIHHYTKVADLSP-IPVVLYSVPANTGLDLPVDAVV--TLSQHPNIVGMKDSGGDVTRIG 183 Query: 184 QCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243 V + R+Q F L G L+++ +GA G V + N LG + Q+ + A Sbjct: 184 LIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVCALANVLGAQVCQLERLCCTGQWEDAQ 243 Query: 244 NYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 Q + N V FG+ K IM G GP R PLQ+ S AE + + Sbjct: 244 KLQHRLIEP-NAAVTRRFGIPGLKKIMDWF-GYYGGPCRAPLQELS-----PAEEEALRM 296 Query: 304 DFLS 307 DF S Sbjct: 297 DFTS 300 >3LCG-A nrPDB Length = 319 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 86/300 (28%), Positives = 150/300 (50%), Gaps = 12/300 (4%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 L+G++AA +TP + ++ + + + V + + +QG+ ++V G+TGE S+SER Q Sbjct: 25 TNLRGVMAALLTPFDQQQALDKASLRRLVQFNI-QQGIDGLYVGGSTGEAFVQSLSEREQ 83 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 V E + K K+ ++I HVG +S ESQ+LA A G D ++ + PF+ P++ + Sbjct: 84 VLEIVAEEAKGKI-KLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYY-PFSFEEHC 141 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 + + + +A LP Y+IPAL+GVK+ +++ L +P LK + DL Q Sbjct: 142 DHYRAIIDSADGLPMVVYNIPALSGVKLTLDQI--NTLVTLPGVGALKQTSGDLYQMEQI 199 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + G DE S L+ GA G +GSTYN +G + +++A ++ D A Sbjct: 200 --RREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKL 257 Query: 246 QFCIQRFINFVVKLGF--GVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 Q + I+ ++K G G+ M +VS + R P ++ +A + L Sbjct: 258 QTECNKVIDLLIKTGLFRGLKTVLHYMDVVS---VPLCRKPFGPVDEKYLPELKALAQQL 314 >4N4Q-A nrPDB Length = 296 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 85/291 (29%), Positives = 155/291 (53%), Gaps = 9/291 (3%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K +GL A +TP T++G+++ + + + V++LV++Q V I++ G+TGE L LS +++ Sbjct: 4 FDKFKGLFPAMVTPFTKDGKLHKAGVKEVVNFLVEKQKVDGIYITGSTGEFLLLSFEDKK 63 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 +V + V + +I +G+L+++E++ELA+ A E+ D I+ I P++ ++ + Sbjct: 64 EVMK-LVAEANAGRVTLIAQIGSLNIEETKELAKLAKELKYDAISAITPYYYN-FSFNET 121 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 ++ +E++ AA +P Y++P L G K+ ++ G L +I G K+ TDL F + Sbjct: 122 HHYYEEISKAA-DIPMLIYYLPQLAGQKVSTDQF--GKLLEIKNVIGSKYGATDLFAFER 178 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 + + + F+F DE L L MGA G +GSTYN K N +++A+E D + Sbjct: 179 LMSKYPDK--LFMFAWDEALAMGLTMGAKGFIGSTYNVNAKGANAIIKAWEANDKEAVMK 236 Query: 245 YQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDS 295 ++ ++ G + KAIM L G+ G R P + E Sbjct: 237 LTHTYNDYVLDLISKGL-MQSLKAIMRL-HGVDAGYTRKPFWRYEDEEIKK 285 >3CPR-A nrPDB Length = 304 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 80/299 (26%), Positives = 148/299 (49%), Gaps = 11/299 (3%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 + A +TP TE+G+I+ + + YLV ++G+ ++ + GTTGE + + +E+ ++ Sbjct: 17 FGTVGVAMVTPFTESGDIDIAAGREVAAYLV-DKGLDSLVLAGTTGESPTTTAAEKLELL 75 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + + D+ ++I VG + + S ELA+ AA GADG+ V+ P++ KP + +L +F Sbjct: 76 KAVREEVGDR-AKLIAGVGTNNTRTSVELAEAAASAGADGLLVVTPYYSKPSQEGLLAHF 134 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 AAA +P Y IP +G+ I ++ + L ++PT +K + DL+ + Sbjct: 135 --GAIAAATEVPICLYDIPGRSGIPIESDTMRR--LSELPTILAVKDAKGDLVAATSLI- 189 Query: 188 QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQF 247 ++ A+ G D L L +G +G + + ++ +FE+ D A Sbjct: 190 --KETGLAWYSGDDPLNLVWLALGGSGFISVIGHAAPTALRELYTSFEEGDLVRAREINA 247 Query: 248 CIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFL 306 + + +LG GVS KA + L GI +G PRLP+ + + ++ +K L Sbjct: 248 KLSPLVAAQGRLG-GVSLAKAALRL-QGINVGDPRLPIMAPNEQELEALREDMKKAGVL 304 >3SI9-A nrPDB Length = 315 Score = 258 bits (658), Expect = 4e-69, Method: Composition-based stats. Identities = 73/305 (23%), Positives = 126/305 (41%), Gaps = 12/305 (3%) Query: 4 PKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER 63 P L+G V A ITP +NG I+ +V++ + QG+ + GTTGE +L+ E Sbjct: 19 PGSMLKGAVTALITPFDDNGAIDEKAFCNFVEWQIT-QGINGVSPVGTTGESPTLTHEEH 77 Query: 64 RQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDI 123 +++ E V + K V+ G+ S E+ ELA+HA + GAD + V+ P++ +P + + Sbjct: 78 KRIIELCVEQV-AKRVPVVAGAGSNSTSEAVELAKHAEKAGADAVLVVTPYYNRPNQRGL 136 Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183 +F A A ++P Y+IP+ + + + E + + G+K + + Sbjct: 137 YTHFSS--IAKAISIPIIIYNIPSRSVIDMAVETM-RDLCRDFKNIIGVKDATGKIERAS 193 Query: 184 QCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243 + + + F L G D L G G + + N K Q+ A D+ AL Sbjct: 194 EQ-REKCGKDFVQLSGDDCTALGFNAHGGVGCISVSSNVAPKLCAQLHAACLCSDYKTAL 252 Query: 244 NYQFCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLK 301 + F+ G+ A + L I R P+ S + L Sbjct: 253 KLNDLLMPLNRAVFIEPSPAGIKYAAAKLGLCGTI----VRSPIVPLSDTTKKIIDEALY 308 Query: 302 SLDFL 306 L Sbjct: 309 HAGLL 313 >3NA8-A nrPDB Length = 315 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 70/297 (23%), Positives = 133/297 (44%), Gaps = 8/297 (2%) Query: 7 KLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQV 66 + G++ TITP +G ++ +G+ ++ L+ + GV I G+TGEG LS E +V Sbjct: 24 SIHGIIGYTITPFAADGGLDLPALGRSIERLI-DGGVHAIAPLGSTGEGAYLSDPEWDEV 82 Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + + ++ I+ V L+ ++ AQ A +GA+ + V+ + K ++ + Sbjct: 83 VDFTLKTVAHRV-PTIVSVSDLTTAKTVRRAQFAESLGAEAVMVLPISYWKLNEAEVFQH 141 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV 186 + A +P Y+ P +G+ + E +L I+ ++ +K S D+ + Sbjct: 142 Y--RAVGEAIGVPVMLYNNPGTSGIDMSVELILR-IVREVDNVTMVKESTGDIQRM-HKL 197 Query: 187 DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + + F G + L A V GA G + N + Q+ +A D A Sbjct: 198 RLLGEGRVPFYNGCNPLALEAFVAGAKGWCSAAPNLIPTLNGQLYQAVLDGDLEKARALF 257 Query: 247 FCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSL 303 + ++F+++ G + KA + L SG+ +G PRLP+Q E + L+ L Sbjct: 258 YRQLPLLDFILRRGLP-TTIKAGLGL-SGLEVGAPRLPVQALDTEGCRYLQGLLEEL 312 >3DI0-A nrPDB Length = 295 Score = 243 bits (620), Expect = 9e-65, Method: Composition-based stats. Identities = 70/295 (23%), Positives = 122/295 (41%), Gaps = 13/295 (4%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 +G+ A TP T N ++N + +V++L+ E + I VNGTT E +L+ E+ + Sbjct: 3 HLFEGVGVALTTPFT-NNKVNIEALKTHVNFLL-ENNAQAIIVNGTTAESPTLTTDEKER 60 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + + V DK VI G ++S + + A +GAD I +I P++ K + ++ Sbjct: 61 ILK-TVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVK 119 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 +F E A A LP Y++P+ T + I E + IL + P LK + D + Sbjct: 120 HF--EAIADAVKLPVVLYNVPSRTNMTIEPETV--EILSQHPYIVALKDATNDFEYLEEV 175 Query: 186 VDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + FA G D+ ++ G G + N + K+ + +A + L+ Sbjct: 176 KKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSG-----LDI 230 Query: 246 QFCIQRFINFVVKLGFGVSQT-KAIMTLVSGIPMGPPRLPLQKASREFTDSAEAK 299 Q + + L ++ +T G RLPL T Sbjct: 231 QDQFKPIGTLLSALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRET 285 >1W37-A nrPDB Length = 294 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 70/291 (24%), Positives = 126/291 (43%), Gaps = 14/291 (4%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 ++ ITP T++ I+ + + + L++ +G+ +FVNGTTG G SLS E+ + + Sbjct: 4 IITPIITPFTKDNRIDKEKLKIHAENLIR-KGIDKLFVNGTTGLGPSLSPEEKLENLK-- 60 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 D +++I VG L+L ++ LA+ + + GIA AP++ ++ L+ + K Sbjct: 61 --AVYDVTNKIIFQVGGLNLDDAIRLAKLSKDFDIVGIASYAPYYYPRMSEKHLVKYFKT 118 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 + +P P Y Y+ P TG I A + +I F G+K + +++ + Sbjct: 119 LCEVSPH-PVYLYNYPTATGKDIDA-----KVAKEIGCFTGVKDTIENIIHTLD--YKRL 170 Query: 191 QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQ 250 G D + + G G V + NYL + T + + ++ AL QF Sbjct: 171 NPNMLVYSGSDMLIATVASTGLDGNVAAGSNYLPEVTVTIKKLAMERKIDEALKLQFLHD 230 Query: 251 RFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLK 301 I G +S + G +G PR P+ E K++ Sbjct: 231 EVIEASRIFG-SLSSNYVLTKYFQGYDLGYPRPPIFPLDDEEERQLIKKVE 280 >4PTN-A nrPDB Length = 343 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 75/289 (25%), Positives = 135/289 (46%), Gaps = 12/289 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 G++ T T +G+++ +D L+K GV +F G+ GE L ER+ +A Sbjct: 32 FTGIIPPVSTIFTADGQLDKPGTAALIDDLIKA-GVDGLFFLGSGGEFSQLGAEERKAIA 90 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + D+ V+I G + +E+ EL+QHA + GADGI VI P++ K ++ LI + Sbjct: 91 RFAID-HVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWK-VSEANLIRY 148 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 ++VA + LP Y+ PALTG + L+ + D G+K + + + Sbjct: 149 FEQVAD-SVTLPVMLYNFPALTGQDLTP-ALVKTLADSRSNIIGIKDTIDSVAHLRSMIH 206 Query: 188 --QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + F L G D+ L + L++G GA+ ++ N+ + + +L+A+ D + A Y Sbjct: 207 TVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGY 266 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMG----PPRLPLQKASR 290 + + I + +L ++ G P+ PP PL + + Sbjct: 267 HQTLLQ-IPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRK 314 >3N2X-A nrPDB Length = 298 Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 75/289 (25%), Positives = 135/289 (46%), Gaps = 12/289 (4%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 G++ T T +G+++ +D L+K GV +F G+ GE L ER+ +A Sbjct: 3 FTGIIPPVSTIFTADGQLDKPGTAALIDDLIKA-GVDGLFFLGSGGEFSQLGAEERKAIA 61 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + D+ V+I G + +E+ EL+QHA + GADGI VI P++ K ++ LI + Sbjct: 62 RFAID-HVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWK-VSEANLIRY 119 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 ++VA + LP Y+ PALTG + L+ + D G+K + + + Sbjct: 120 FEQVAD-SVTLPVMLYNFPALTGQDLTP-ALVKTLADSRSNIIGIKDTIDSVAHLRSMIH 177 Query: 188 --QNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + F L G D+ L + L++G GA+ ++ N+ + + +L+A+ D + A Y Sbjct: 178 TVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGY 237 Query: 246 QFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMG----PPRLPLQKASR 290 + + I + +L ++ G P+ PP PL + + Sbjct: 238 HQTLLQ-IPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRK 285 >2NUX-A nrPDB Length = 288 Score = 231 bits (588), Expect = 4e-61, Method: Composition-based stats. Identities = 73/294 (24%), Positives = 135/294 (45%), Gaps = 16/294 (5%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 +++ ITP + G++N + + L+ E+G+ IFVNGTTG G +LS E+RQ Sbjct: 3 IISPIITPFDKQGKVNVDALKTHAKNLL-EKGIDAIFVNGTTGLGPALSKDEKRQNL--- 58 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 D ++I VG+L+L + EL + + E+ G++ +P++ + L + +E Sbjct: 59 -NALYDVTHKLIFQVGSLNLNDVMELVKFSNEMDILGVSSHSPYYFPRLPEKFLAKYYEE 117 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 +A + + Y Y+ PA TG I IL +P +G+K ++ DL + + Sbjct: 118 IARIS-SHSLYIYNYPAATGYDIPP-----SILKSLP-VKGIKDTNQDLAHSLE--YKLN 168 Query: 191 QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQ 250 G + L+ ++ G V S N++ + + + +Q AL Q I Sbjct: 169 LPGVKVYNGSN-TLIYYSLLSLDGVVASFTNFIPEVIVKQRDLIKQGKLDDALRLQELIN 227 Query: 251 RFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLD 304 R + + K G +S ++ G +G PR P+ + E S + +++ L Sbjct: 228 RLADILRKYG-SISAIYVLVNEFQGYDVGYPRPPIFPLTDEEALSLKREIEPLK 280 >5UI3-D nrPDB Length = 341 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 67/302 (22%), Positives = 114/302 (37%), Gaps = 28/302 (9%) Query: 6 KKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 KKL+ L+ A TP NG+ + V + + E GV+ + V GTTGEG +S E Sbjct: 41 KKLR-LITAIKTPYLANGKFDLPAYDALVSHQI-ENGVEGLIVGGTTGEGHLMSWDEHVM 98 Query: 66 VAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILI 125 + V DK VI + G+ S +E+ + +G I P++ K +L Sbjct: 99 LIAHTVNAFGDKTA-VIGNTGSNSTREALHATEQGFAVGMHASLQINPYYGKTSKAGLLN 157 Query: 126 NFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQC 185 +F A P Y++P TG I + +++ + F G+K + Sbjct: 158 HFN----AVLNEGPAVVYNVPGRTGQDIPDDVVMEIC--QHSNFLGMKECTGN-----SR 206 Query: 186 VDQNRQQQFAFLFG-VDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAF----EQKDFS 240 + + G DE + GA G + T N + ++++ D Sbjct: 207 IKNYTSKGVNCWSGNDDESHDARHSNGAVGVISVTSNVIPGLMHKLMHGSPDPQLNADLK 266 Query: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300 + + FC I+ L + + L P +PL +A RE K+ Sbjct: 267 ELMAWMFCEPNPISLNTALAM-CGLARPVFRL--------PYVPLSRAQREKGAVLLNKV 317 Query: 301 KS 302 + Sbjct: 318 QE 319 >2R91-A nrPDB Length = 286 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 66/295 (22%), Positives = 134/295 (45%), Gaps = 18/295 (6%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 +VA IT G ++ + +V + +GV +FV GTTG G +LS+ E+ ++ + Sbjct: 3 IVAPVITTF-RGGRLDPELFANHVKN-ITSKGVDVVFVAGTTGLGPALSLQEKMELTDAA 60 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 + + +VI+ V +L+ E+ LA++A GA+ +A + P++ ++ + + ++ Sbjct: 61 TSAAR----RVIVQVASLNADEAIALAKYAESRGAEAVASLPPYYFPRLSERQIAKYFRD 116 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 + +A ++P + Y+ PA G + A ++ +G+K ++ L + Sbjct: 117 LCSAV-SIPVFLYNYPAAVGRDVDARA-----AKELGCIRGVKDTNESLAHT--LAYKRY 168 Query: 191 QQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQ 250 Q G D + ++ + G V S+ NYL + + +A D A + QF + Sbjct: 169 LPQARVYNGSDSLVFASFAVRLDGVVASSANYLPELLAGIRDAVAAGDIERARSLQFLLD 228 Query: 251 RFINFVVKLGFGVSQTKAIMTLVSGIPMGPPR---LPLQKASREFTDSAEAKLKS 302 + +G+ + ++ + G G PR PL + + +A AK KS Sbjct: 229 EIVESARHIGYA-AAVYELVEIFQGYEAGEPRGPVYPLDPEEKAWLRAAVAKAKS 282 >4DPQ-A nrPDB Length = 360 Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 62/304 (20%), Positives = 113/304 (37%), Gaps = 22/304 (7%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 ++ A TP +G + V+ + + G + + V GTTGEG +S E + Sbjct: 63 VITAIKTPYLPDGRFDLEAYDDLVNIQI-QNGAEGVIVGGTTGEGQLMSWDEHIMLIGHT 121 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 V + +VI + G+ S +E+ + +G I P++ K + ++ +F Sbjct: 122 VNCFGGSI-KVIGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSIEGLIAHFQ-- 178 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 + P Y++P TG I + L + P G+K + + V++ Sbjct: 179 --SVLHMGPTIIYNVPGRTGQDIPPRAIFK--LSQNPNLAGVKECVGN-----KRVEEYT 229 Query: 191 QQQFAFLFG-VDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCI 249 + G DE S GATG + T N + +++ FE ++ S LN + Sbjct: 230 ENGVVVWSGNDDECHDSRWDYGATGVISVTSNLVPGLMRKLM--FEGRNSS--LNSKLLP 285 Query: 250 QRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFLSFT 309 F G++ A + + + RLP +K + F Sbjct: 286 LMAWLFHEPNPIGINTALAQLGVSRPVF----RLPYVPLPLSKRLEFVKLVKEIGREHFV 341 Query: 310 DLKD 313 KD Sbjct: 342 GEKD 345 >3TUU-A nrPDB Length = 346 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 60/299 (20%), Positives = 110/299 (36%), Gaps = 22/299 (7%) Query: 11 LVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEW 70 L+ A TP +G + V+ + + G + + V GTTGEG +S E + Sbjct: 49 LITAIKTPYLPDGRFDLEAYDALVNMQIVD-GAEGVIVGGTTGEGQLMSWDEHIMLIGHT 107 Query: 71 VTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 V + +VI + G+ S +E+ + +G I P++ K + ++ +F Sbjct: 108 VNCFGGSI-KVIGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSLEGLVSHF--- 163 Query: 131 VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNR 190 + P P Y++P+ TG I + + + G+K + + Q Sbjct: 164 -ESVLPMGPTVIYNVPSRTGQDIPPGVI--HTVAQSANLAGVKECVGN-----DRIKQYT 215 Query: 191 QQQFAFLFGVDEQLLSA-LVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCI 249 + G D+Q A GATG + T N + Q+ F+ K+ SL + Sbjct: 216 DNRIVVWSGNDDQCHDAKWDYGATGVISVTSNLIPGLMRQL--LFKGKNPSLNAKIMPLV 273 Query: 250 QRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKSLDFLSF 308 G++ A + +V + RLP +K + +F Sbjct: 274 NWLFE--EPNPIGLNTALAQLGVVRPVF----RLPYVPLPLAKRVEFVNIVKEIGRENF 326 >4UXD-A nrPDB Length = 297 Score = 207 bits (527), Expect = 6e-54, Method: Composition-based stats. Identities = 64/283 (22%), Positives = 130/283 (45%), Gaps = 16/283 (5%) Query: 5 KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K +G+V ITP+ +G I+++ + YL + V +F G+TG ++ ER+ Sbjct: 22 KHMYKGIVCPMITPLDAHGNIDYNATNILIKYL-EGINVDYLFPMGSTGVFPYFTLKERK 80 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 + +V + K ++ VG+ S+ E EL + + +IG + ++ P+++K + I Sbjct: 81 DFLK-FVRENSKK--PIMAGVGSSSINEVNELMKFSMDIGIEAAVLMPPYYIKLNQEAIY 137 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 ++ KE+ + + + Y+IP T KI E + + + + +G+K S D+ F + Sbjct: 138 -HYYKEILS-SNDMDLLIYNIPQFTN-KIDPETV-KNLKSEFSSVKGVKDSSADIRGFME 193 Query: 185 CVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALN 244 + + FA G D+ L ++L +GA+G V T N+ ++ ++ + + + + Sbjct: 194 MLSLS-DDDFAVFQGQDDLLFTSLELGASGGVCGTTNF----SDGIVRLYHEYKNNREMA 248 Query: 245 YQFCIQRFINFVVKLGFGVSQ--TKAIMTLVSGIPMGPPRLPL 285 + I + KLG + I G R P+ Sbjct: 249 LKIEKNDVIPLMKKLGKYQFPNAYYEYFYKKNNINGGY-RPPM 290 >4XKY-B nrPDB Length = 300 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 66/303 (21%), Positives = 127/303 (41%), Gaps = 12/303 (3%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 L G++ +TP+ ++ ++ + + +++L+ GV +FV GTTGE SLS R ++ Sbjct: 5 LSGIIPPLVTPLLDDDVLDVEGLQRLIEHLIA-GGVHALFVLGTTGESQSLSYKLRMEMI 63 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + K +L V++ + S+ ES LA AA+ GAD + P++ + LI F Sbjct: 64 KNTCRIAKGRL-PVLVCISDTSIVESVNLACLAADHGADAVVSAPPYYFATGQPE-LIEF 121 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 + + P + Y++P T V + + + P G K S + + F + Sbjct: 122 YEHLLPQLPLP-LFLYNMPTHTKVNFAPATIQR--IAENPGVIGFKDSSANTVYFQSVMY 178 Query: 188 QNRQ-QQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQ 246 + F+ L G +E + ++++GA G V N + + A + D Q Sbjct: 179 AMKDNPDFSMLVGPEEIMAESVLLGAHGGVNGGANMFPELYVSLYNAAKNADMEEVRRLQ 238 Query: 247 FCIQRFINFVVKLG----FGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLKS 302 + + + +G + K ++L+ GI P K + L++ Sbjct: 239 EKVMQISATIYTVGQHGSSYLKGLKCALSLL-GICSDYVAAPFHKFEQRERGKIWKALQN 297 Query: 303 LDF 305 L Sbjct: 298 LGV 300 >5C54-A nrPDB Length = 312 Score = 193 bits (491), Expect = 8e-50, Method: Composition-based stats. Identities = 69/303 (22%), Positives = 119/303 (39%), Gaps = 17/303 (5%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 G++ +TP+ +G ++ + + VD+L+ GV +F G++GE L+ ++R+ Sbjct: 6 FTGVIPPVMTPLHADGSVDVESLRKLVDHLIN-GGVDGLFALGSSGEAAFLTRAQRKLAL 64 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 + ++ V V + EL + A E GA+G+ APF+ + +I +F Sbjct: 65 TTIIEHTAGRV-PVTAGVIETTTARVIELVEDALEAGAEGLVATAPFYTRTHDVEIEEHF 123 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCV- 186 +++ AAAP LP + Y+IP + LL L K G K S + + Sbjct: 124 -RKIHAAAPELPLFAYNIPVSVHSNLNPVMLL--TLAKDGVLAGTKDSSGNDGAIRSLIE 180 Query: 187 ---DQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243 D +QF L G + + A + GA G V N + + ++ A Sbjct: 181 ARDDAGLTEQFKILTGSETTVDFAYLAGADGVVPGLGNVDPAAYAALAKLCLDGKWAEAA 240 Query: 244 NYQFCIQRFINFV--------VKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDS 295 Q I + V G+ K + + I +P Q S E T Sbjct: 241 ALQKRINHLFHIVFVGDTSHMSGSSAGLGGFKTALAHLGIIESNAMAVPHQSLSDEETAR 300 Query: 296 AEA 298 A Sbjct: 301 IHA 303 >3D0C-A nrPDB Length = 314 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 68/304 (22%), Positives = 120/304 (39%), Gaps = 17/304 (5%) Query: 6 KKLQGLVAATITPMTE-NGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K+ + I P E EI++ + V++L+ + G++ I NG TGE +L++ E + Sbjct: 10 KRFSTISGINIVPFLEGTREIDWKGLDDNVEFLL-QNGIEVIVPNGNTGEFYALTIEEAK 68 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 QVA + V+ +G S+ + EL + A + GAD + + P T Sbjct: 69 QVATRVTELVNGR-ATVVAGIG-YSVDTAIELGKSAIDSGADCVMIHQPVH-PYITDAGA 125 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 + + + + A A Y+ L+ I+ L + G+K++ D+ Q Sbjct: 126 VEYYRNIIEALDAPSIIYFKDAHLSDDVIK-------ELAPLDKLVGIKYAINDIQRVTQ 178 Query: 185 CVDQ-NRQQQFAFLFGVDEQLLSALVM-GATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA 242 + + AF+ G E+ GA G N +K+ +LEA E+ + Sbjct: 179 VMRAVPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEEGNQEKI 238 Query: 243 LNYQFCIQRF--INFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300 + + F + G V K M + G+ G R P+ S E L Sbjct: 239 WDVWEDVVPFEDLRAKHNNGNNVVIIKEAMEQL-GLRAGVTREPVNPLSPNDRLELEELL 297 Query: 301 KSLD 304 KS + Sbjct: 298 KSWN 301 >2HMC-A nrPDB Length = 344 Score = 174 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 58/275 (21%), Positives = 108/275 (39%), Gaps = 15/275 (5%) Query: 8 LQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVA 67 G++ A +TP ++ +F + + L+ + G+ + G+ G+ L+ +R + Sbjct: 27 FSGVIPALMTPCRQDRTPDFDALVRKGKELIAD-GMSAVVYCGSMGDWPLLTDEQRMEGV 85 Query: 68 EEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINF 127 E V G VI+ GA++ + A HA ++GA G+ VI + Sbjct: 86 ERLVKAG----IPVIVGTGAVNTASAVAHAVHAQKVGAKGLMVIPRVLSRGSVIAAQKAH 141 Query: 128 LKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDT--DLLDFGQC 185 K + +AAP +P Y+ P G RA+ + + G K D+ + Sbjct: 142 FKAILSAAPEIPAVIYNSP-YYGFATRADLFF-ALRAEHKNLVGFKEFGGPADMRYAAEN 199 Query: 186 VDQNRQQQFAFLFGVDEQLLSALV-MGATGAVGSTYNYLGKKTNQMLE---AFEQKDFS- 240 + +R + + GVD ++ V GATGA+ N L K+ + + A + D Sbjct: 200 I-TSRDDEVTLMIGVDTAVVHGFVNCGATGAITGIGNVLPKEVIHLCKLSQAAAKGDADA 258 Query: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSG 275 A + + G + M ++ G Sbjct: 259 RARALELEQALAVLSSFDEGPDLVLYFKYMMVLKG 293 >3E96-A nrPDB Length = 316 Score = 157 bits (397), Expect = 6e-39, Method: Composition-based stats. Identities = 72/309 (23%), Positives = 118/309 (38%), Gaps = 17/309 (5%) Query: 6 KKLQGLVAATITPMTE-NGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64 K L+ + ITP + +G I++ + VD + + G+ I G T E +LS+ E + Sbjct: 10 KALETISGIPITPFRKSDGSIDWHHYKETVDR-IVDNGIDVIVPCGNTSEFYALSLEEAK 68 Query: 65 QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDIL 124 + V + V+ +G + + EL A GAD + + P T + Sbjct: 69 EEVRRTVEYVHGRAL-VVAGIG-YATSTAIELGNAAKAAGADAVMIHMPIH-PYVTAGGV 125 Query: 125 INFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQ 184 + +++ A Y+ P +I L+D L + G+K++ DL F + Sbjct: 126 YAYFRDIIEALDFPSLVYFKDP-----EISDRVLVD--LAPLQNLVGVKYAINDLPRFAK 178 Query: 185 CVDQNRQQ-QFAFLFGVDEQLLSALVM-GATGAVGSTYNYLGKKTNQMLEAFEQKDFSLA 242 V ++ Q A++ G E+ GA G N L +K +MLEA D Sbjct: 179 VVRSIPEEHQIAWICGTAEKWAPFFWHAGAKGFTSGLVNLLPQKAVEMLEALRNNDNDAV 238 Query: 243 LNYQFCIQRFINFVVKL--GFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300 I F + K G V K M ++ G R P+ + S E L Sbjct: 239 WRIWEDIVPFEDLRGKYNQGNNVVVIKEAMEMLRQ-NAGVTRAPVNELSNEDKQLVTELL 297 Query: 301 KSLDFLSFT 309 S L T Sbjct: 298 SSWKLLQPT 306 >4UR8-A nrPDB Length = 311 Score = 130 bits (327), Expect = 8e-31, Method: Composition-based stats. Identities = 54/295 (18%), Positives = 104/295 (35%), Gaps = 17/295 (5%) Query: 9 QGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAE 68 GL++ +T G ++V++L +F G TGE SL E + Sbjct: 12 SGLLSFPVTHFDAEGRFAADSYREHVEWL-AGYKAPVLFAAGGTGEFFSLKPDEIPTIVA 70 Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFL 128 + ++ G + + ++A+ ++GADGI ++ + + + + + Sbjct: 71 AAKEVAGETA--IVSGCG-YGTEIAVDIARSVEKVGADGILLLPHYLIDAPQEGLYAHIK 127 Query: 129 KEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQ 188 K + + Y+ ++A+ L D+ P G K D+ Q + Sbjct: 128 K--VCQSVGIGVMVYN---RDNSVLQADTLARLC-DECPNLVGFKDGTGDIGLVRQITAK 181 Query: 189 NRQQQFAFLFGVDEQLLSALVMGATGAV---GSTYNYLGKKTNQMLEAFEQKDFSLALNY 245 + +L G+ L A G + +N++ N+ A + + Sbjct: 182 M-GDRLMYLGGMPTAELFAEAYLGAGFTTYSSAVFNFVPGLANEFYAALRAGERATCERI 240 Query: 246 QFCIQRFINFV--VKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEA 298 + G+ VS KA + L G GP R PL+ + E EA Sbjct: 241 LVDFFYPFMAIRNRAKGYAVSAVKAGVRL-QGFNAGPVRAPLKDLTNEEIGMLEA 294 >3FKK-A nrPDB Length = 309 Score = 110 bits (276), Expect = 7e-25, Method: Composition-based stats. Identities = 51/308 (16%), Positives = 106/308 (34%), Gaps = 12/308 (3%) Query: 2 AFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVS 61 + P+ +G+ T + G+++ + + VD+++ + G + + E +++ Sbjct: 5 STPRH--RGIFPVVPTTFADTGDLDLASQKRAVDFMI-DAGSDGLCILANFSEQFAITDD 61 Query: 62 ERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPW-- 119 ER V + + VI+ S + + A ++GA + + P+ + Sbjct: 62 ER-DVLTRTILEHVAGRVPVIVTTSHYSTQVCAARSLRAQQLGAAMVMAMPPYHGATFRV 120 Query: 120 TKDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLK-FSDTD 178 + + F V + A A+P PA +G + A L + +I K + Sbjct: 121 PEAQIFEFYARV-SDAIAIPIMVQDAPA-SGTALSAP-FLARMAREIEQVAYFKIETPGA 177 Query: 179 LLDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKD 238 + + G + L A + + + +LEA+ + Sbjct: 178 ANKLRELIRLGGDAIEGPWDGEEAITLLADLHAGATGAMTGGGF-PDGIRPILEAWREGR 236 Query: 239 FSLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEA 298 A IN + G+ KA+M I PR P+ + + A Sbjct: 237 HDDAYARYQAWLPLINHENRQS-GILTAKALMREGGVIASERPRHPMPELHPDTRAELLA 295 Query: 299 KLKSLDFL 306 + LD L Sbjct: 296 IARRLDPL 303 >6DAO-B nrPDB Length = 331 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 58/317 (18%), Positives = 106/317 (33%), Gaps = 31/317 (9%) Query: 7 KLQGLVAATITPMTENGE-------INFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLS 59 + G TP T + ++ + V+ L+ GV I GT GE +L+ Sbjct: 15 DINGAWTIMPTPSTPDASDWRSTNTVDLDETARIVEELIAA-GVNGILSMGTFGECATLT 73 Query: 60 VSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPW 119 E+R V + ++ AL+ +E + +IGA+G + P ++K Sbjct: 74 WEEKRDYVSTVVETIRGRV-PYFCGTTALNTREVIRQTRELIDIGANGTMLGVPMWVKMD 132 Query: 120 TKDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDL 179 + F ++VA A P Y P + KIP K+ L Sbjct: 133 LPTAVQ-FYRDVAGAVPEAAIAIYANPEAFKFDFP--RPFWAEMSKIPQVVTAKY----L 185 Query: 180 LDFGQCVDQNRQQQFAFLFGVDEQLLSA-------LVMGATGAVGSTYNYLGKKTNQMLE 232 +D FL D+ +A ++GA+ + +++ Sbjct: 186 GIGMLDLDLKLAPNIRFLPHEDDYYAAARINPERITAFWSSGAMCGPATAI-MLRDEVER 244 Query: 233 AFEQKDFSLALNYQFCIQRFINFVVKLG-------FGVSQTKAIMTLVSGIPMGPPRLPL 285 A D+ A ++ + + G + + KA M + GP R P Sbjct: 245 AKSTGDWIKAKAISDDMRAADSTLFPRGDFSEFSKYNIGLEKARMDAAGWLKAGPCRPPY 304 Query: 286 QKASREFTDSAEAKLKS 302 ++ A+ K+ Sbjct: 305 NLVPEDYLVGAQKSGKA 321 >4OQY-A nrPDB Length = 290 Score = 35.0 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 49/142 (34%), Gaps = 25/142 (17%) Query: 1 MAFPKKKLQGLVA---ATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNG------- 50 M+ + GL A + +NG + + + + G Sbjct: 1 MSKQSVTVIGLGPMGQAMVNTFLDNG-------HEVTVWNRTASKAEALVARGAVLAPTV 53 Query: 51 ----TTGEGLSLSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGAD 106 + E + LS+++ V +VI ++ + + +++E A+ AA+ GA Sbjct: 54 EDALSANELIVLSLTDYDAVYAILEPVTGSLSGKVIANLSSDTPDKAREAAKWAAKHGAK 113 Query: 107 ----GIAVIAPFFLKPWTKDIL 124 G+ V P KP + Sbjct: 114 HLTGGVQVPPPLIGKPESSTYY 135 >6EQN-B nrPDB Length = 425 Score = 34.3 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 60/199 (30%), Gaps = 25/199 (12%) Query: 54 EGLSLSVSERRQVAEEWVTKGK-DKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIA 112 E + + S + A V K D V GA S LA + A V Sbjct: 99 ESYTYTGSHKINSALAHVYYAKLDNAKFVTTETGAGQWGSSVALASALFRMKAHIFMVRT 158 Query: 113 PFFLKPWTKDILINFLKEVAAAAPALPFY-------YYHIPALTGVKIRAEELLDGILDK 165 ++ KP+ K ++ + EV + L + + P G+ I D + Sbjct: 159 SYYAKPYRKYMMQMYGAEVHPSPSDLTEFGRQLLAKDSNHPGSLGIAIS-----DAVEYA 213 Query: 166 IPTFQGLKFSDTDLLD---FGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNY 222 G K+ +++ + + ++ L G D + G VG NY Sbjct: 214 HKN--GGKYVVGSVVNSDIMFKTIAGMEAKKQMELIGEDPDYI-------IGVVGGGSNY 264 Query: 223 LGKKTNQMLEAFEQKDFSL 241 + + Sbjct: 265 AALAYPFLGDELRSGKVRR 283 >4FQ5-B nrPDB Length = 281 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 47/109 (43%), Gaps = 15/109 (13%) Query: 22 NGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQV 81 +G+ + + + D V G + + G G +ER VT+ D + Sbjct: 81 DGDSDRCAL-ELSDARVDVMGYACLVAIMSMGHGYHRVSAERL----RNVTENNDAATPI 135 Query: 82 IIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE 130 I GAL + +GA +AV+ P ++KP T+ +++++++ Sbjct: 136 ITSAGAL--IDGIR------ALGAKRVAVVTP-YMKPLTE-LVVDYIRH 174 >2ZVI-A nrPDB Length = 425 Score = 32.3 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 52 TGEGLSLS-VSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAV 110 TG + ++E +Q+ +E + K + G + ++ A+ AAE+GAD + Sbjct: 195 TGLAPFETRIAEGKQILKETYEQTGHKTLYAVNLTG--RTADLKDKARRAAELGADALLF 252 Query: 111 IAPFFLKPWTKDILINFLKEVAAAAPALPFYYYHIPALTG 150 + + + A P +P PA++G Sbjct: 253 NVFAYGLDVMQGL---------AEDPEIPVPIMAHPAVSG 283 >1M1B-A nrPDB Length = 295 Score = 32.0 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 40/117 (34%), Gaps = 9/117 (7%) Query: 73 KGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKEVA 132 +++ I G L E+ + A+ GAD I + + K + F+K Sbjct: 155 CIVARVEAFIAGWG---LDEALKRAEAYRNAGADAILMHS----KKADPSDIEAFMKAWN 207 Query: 133 AAAP--ALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVD 187 P +P YY P + ++ + + ++ + + D V+ Sbjct: 208 NQGPVVIVPTKYYKTPTDHFRDMGVSMVIWANHNLRASVSAIQQTTKQIYDDQSLVN 264 >4ZM6-A nrPDB Length = 858 Score = 31.2 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 16/128 (12%), Positives = 35/128 (27%), Gaps = 18/128 (14%) Query: 154 RAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNRQQQFAFLFGVDEQLLSA-LVMGA 212 +++ K P F + + + G L + +GA Sbjct: 61 SLQQIARNAGHKRPLFIAVDQENGVVRRL----------------GDSGTYLPGNMALGA 104 Query: 213 TGAVGSTYNYLGKKTNQMLEAFEQKDFSLALNYQFCIQRFINFVVKLGF-GVSQTKAIMT 271 G+ + N + ++L + + L+ + V G + + Sbjct: 105 LGSSTAARNVAMAISKELLTLGMNWNLAPVLDVNNNPLNPVIGVRSYGQDPELVARMGLA 164 Query: 272 LVSGIPMG 279 V G G Sbjct: 165 QVEGYQRG 172 >1YIX-A nrPDB Length = 265 Score = 31.2 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 9/71 (12%), Positives = 24/71 (33%), Gaps = 10/71 (14%) Query: 18 PMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSER---RQVAEEWVTKG 74 P+ +N + + + + + G TG + + ++ + G Sbjct: 68 PLNQNDPYDVEDLRRLAAE-------EGVVALGETGLDYYYTPETKVRQQESFIHHIQIG 120 Query: 75 KDKLDQVIIHV 85 ++ VI+H Sbjct: 121 RELNKPVIVHT 131 >3L5A-A nrPDB Length = 419 Score = 31.2 bits (69), Expect = 0.69, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 41/115 (35%), Gaps = 13/115 (11%) Query: 67 AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILIN 126 + V + +I G S + + + QHA +G +PF +P + Sbjct: 307 VNQIVYEHLAGRIPLIASGGINSPESALDALQHADMVGMS-----SPFVTEP-------D 354 Query: 127 FLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLD 181 F+ ++A P + + L + I I+ + +GLK D L Sbjct: 355 FVHKLAEQRPHDINLEFSMADLEDLAI-PHAAFKDIVKMMDYGEGLKKHTRDALR 408 >2LM5-A nrPDB Length = 214 Score = 31.2 bits (69), Expect = 0.71, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 25/64 (39%), Gaps = 12/64 (18%) Query: 19 MTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKL 78 ++G +N + + V+ L E GE LS SE +Q+ + + + Sbjct: 140 FDDDGTLNREDLSRLVNCLTGE------------GEDTRLSASEMKQLIDNILEESDIDR 187 Query: 79 DQVI 82 D I Sbjct: 188 DGTI 191 >1DGU-A nrPDB Length = 183 Score = 31.2 bits (69), Expect = 0.71, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 25/64 (39%), Gaps = 12/64 (18%) Query: 19 MTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKL 78 ++G +N + + V+ L E GE LS SE +Q+ + + + Sbjct: 109 FDDDGTLNREDLSRLVNCLTGE------------GEDTRLSASEMKQLIDNILEESDIDR 156 Query: 79 DQVI 82 D I Sbjct: 157 DGTI 160 >1XZP-A nrPDB Length = 482 Score = 30.4 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 141 YYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDF 182 IP T I E ++ GIL +I G++ DL++ Sbjct: 270 IVTDIPGTTRDVISEEIVIRGILFRIVDTAGVRSETNDLVER 311 >3S5S-A nrPDB Length = 389 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 18/45 (40%) Query: 69 EWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAP 113 E + ++ G L+ E+ L HA +GAD + P Sbjct: 180 EAIHAAAPGASLILDGNGGLTAGEALALVAHARRLGADVALLEQP 224 >1NMO-A nrPDB Length = 247 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 10/77 (12%) Query: 73 KGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLK---PWTKDILINFLK 129 +GK+ + +++ V SQ L A +GAD + V +F K P + + N LK Sbjct: 30 EGKETVQKIVTGV-----TASQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLK 84 Query: 130 EVAAAAPALPFYYYHIP 146 + A + Y +H+P Sbjct: 85 TLL--ANDINLYGWHLP 99 >3R12-A nrPDB Length = 260 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 17/53 (32%), Gaps = 3/53 (5%) Query: 57 SLSVSERRQV---AEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGAD 106 L E V V K K+ +VII L +E + GA Sbjct: 136 MLKAKEWEYVYEDIRSVVESVKGKVVKVIIETCYLDTEEKIAACVISKLAGAH 188 >3KT6-A nrPDB Length = 438 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 2/32 (6%) Query: 15 TITPMTENGEINFSVIGQYVDY--LVKEQGVK 44 +TP G ++ Q +DY L+K+ G K Sbjct: 26 VVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTK 57 >1TYG-A nrPDB Length = 253 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 37/101 (36%), Gaps = 23/101 (22%) Query: 15 TITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGT---TGEGLSLSVSERRQVAEEWV 71 + P T + + + + GV I + +G+G+ + Sbjct: 126 IVLPYTSDDVVLARKLEEL--------GVHAIMPGASPIGSGQGIL-----NPLNLSFII 172 Query: 72 TKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIA 112 + K VI+ G S K++ +A E+GADG+ + Sbjct: 173 EQAK---VPVIVDAGIGSPKDA----AYAMELGADGVLLNT 206 >1PN3-A nrPDB Length = 404 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 15/36 (41%), Gaps = 1/36 (2%) Query: 81 VIIHVGAL-SLKESQELAQHAAEIGADGIAVIAPFF 115 +I G+ + LA E+GAD + P + Sbjct: 4 LITGCGSRGDTEPLVALAARLRELGADARMCLPPDY 39 >4HWF-A nrPDB Length = 88 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 1 MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKE-QGVKNIFVNG 50 ++F +L G V+A T + + G++ + ++ L+ + + I +G Sbjct: 10 ISFEVDRLAGQVSAFETVINKGGKVEEKSLVNLIEMLMNQLLRLDAIIADG 60 >3ZIU-A nrPDB Length = 637 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 7/47 (14%) Query: 19 MTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQ 65 E+ + +D LV+ ++NI +G TGEG + +E Q Sbjct: 264 FDEDNNV------YLIDELVELPHMENIMPSG-TGEGPLATNTEWVQ 303 >3H4T-A nrPDB Length = 404 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 15/36 (41%), Gaps = 1/36 (2%) Query: 81 VIIHVGAL-SLKESQELAQHAAEIGADGIAVIAPFF 115 +I G+ + LA E+GAD + P + Sbjct: 4 LITGCGSRGDTEPLVALAARLRELGADARMCLPPDY 39 >1OYR-A nrPDB Length = 245 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 201 DEQLLSALVMGATGAVGSTYNYLGKKTNQ--MLEAFEQKDFSLALNYQFCIQRFINFVVK 258 ++++ L G G + + Y+ L + TNQ + E+ + K + Q I R + VV Sbjct: 44 EDRVPPFLRGGGKGWITAEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVVD 103 Query: 259 L 259 L Sbjct: 104 L 104 >4CAZ-A nrPDB Length = 490 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 21/162 (12%), Positives = 49/162 (30%), Gaps = 30/162 (18%) Query: 18 PMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDK 77 P+ E ++ ++Y + E Q+ + + Sbjct: 97 PLAETRSVDIVTGADVLEYYA------GLVPA-----------IEGEQIPLRETSFVYTR 139 Query: 78 LDQ--VIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKEVAAAA 135 + V+ +GA + L + A + A + P + P T L E Sbjct: 140 REPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYTEA---- 195 Query: 136 PALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDT 177 +P +++ +G + + L + P + + F+ Sbjct: 196 -GVPDGVFNVLTGSGRE------VGQWLTEHPLIEKISFTGG 230 >1M3S-A nrPDB Length = 186 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 12/34 (35%), Gaps = 1/34 (2%) Query: 81 VIIHVGALSLKESQELAQHAAEI-GADGIAVIAP 113 VII G+ K A A + G I P Sbjct: 83 VIIGSGSGETKSLIHTAAKAKSLHGIVAALTINP 116 >2ABQ-A nrPDB Length = 306 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 35/95 (36%), Gaps = 13/95 (13%) Query: 58 LSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQ--ELAQHAAEIGA---------- 105 L E Q E +T+ + V+ ++ ++ + Q A E GA Sbjct: 107 LIKKEHVQALLEQLTELEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDTSGEA 166 Query: 106 -DGIAVIAPFFLKPWTKDILINFLKEVAAAAPALP 139 + P F+KP ++ K +A+ A+P Sbjct: 167 LHEVLAAKPSFIKPNHHELSELVSKPIASIEDAIP 201 >6G72-D nrPDB Length = 463 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 48/139 (34%), Gaps = 12/139 (8%) Query: 79 DQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKEVAAAAPAL 138 +V+ L + HA +IGA + PFF ++ + F + V+ A Sbjct: 170 IRVLFGEITRILNHIMAVTTHALDIGA-----MTPFFWMFEEREKMFEFYERVSGARMHA 224 Query: 139 PFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNRQQQFAFLF 198 Y P + LLD I + F ++L + + +NR + Sbjct: 225 ---AYIRPGGVHQDL-PLGLLDDIYEFSKNFSLRIDEVEEMLTNNR-IWRNRTVDIGVVT 279 Query: 199 GVDEQL--LSALVMGATGA 215 D S +++ +G Sbjct: 280 AEDALNYGFSGVMLRGSGI 298 >3QN3-A nrPDB Length = 417 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 25/88 (28%), Gaps = 12/88 (13%) Query: 211 GATGAVGSTYNYLGKKTNQM--LEAFEQKDFSLALNYQFCIQRFINFVVKLGFGVS---- 264 G G + + N +++ L+AF Q L + N GVS Sbjct: 62 GGKGVLKAVANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATA 121 Query: 265 ------QTKAIMTLVSGIPMGPPRLPLQ 286 + + G +P+ Sbjct: 122 RAAAAALGMPLYRYLGGANASILPVPMC 149 >4GX0-A nrPDB Length = 565 Score = 28.1 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 17/71 (23%), Gaps = 3/71 (4%) Query: 169 FQGLKFSDTDLLDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAV---GSTYNYLGK 225 T++ C + + +E + GA V N LG Sbjct: 413 IVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGN 472 Query: 226 KTNQMLEAFEQ 236 AF Sbjct: 473 LLEHKESAFLS 483 >4GVL-A nrPDB Length = 462 Score = 28.1 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 17/71 (23%), Gaps = 3/71 (4%) Query: 169 FQGLKFSDTDLLDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAV---GSTYNYLGK 225 T++ C + + +E + GA V N LG Sbjct: 310 IVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGN 369 Query: 226 KTNQMLEAFEQ 236 AF Sbjct: 370 LLEHKESAFLS 380 >4KB5-A nrPDB Length = 408 Score = 28.1 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 15/35 (42%) Query: 19 MTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTG 53 I+ + +G ++Y V +G + G TG Sbjct: 185 YKVTRRIDETSLGAAINYAVNVKGAVIVVAAGNTG 219 >3I9V-3 nrPDB Length = 783 Score = 28.1 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 22/70 (31%), Gaps = 3/70 (4%) Query: 56 LSLSVSERRQVAEEWVTKGKDKLDQV-IIHVGAL-SLKESQELAQHAAEIGADGIAVIAP 113 L E ++ + + + V I+ G L ++ A GA + + P Sbjct: 479 ALLGDKEGSEMVAKAKEAWEKAKNPVLILGAGVLQDTVAAERARLLAERKGAK-VLAMTP 537 Query: 114 FFLKPWTKDI 123 + + Sbjct: 538 AANARGLEAM 547 >2ZHG-A nrPDB Length = 154 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 20/45 (44%), Gaps = 9/45 (20%) Query: 54 EGLSLSVSERRQVAEEWVTKGKDKLDQVII---------HVGALS 89 EG +LS E +Q++ +W + ++ ++ G LS Sbjct: 82 EGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLS 126 >2CZE-A nrPDB Length = 208 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 25/73 (34%), Gaps = 8/73 (10%) Query: 59 SVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKP 118 + ER + + +G L I G A+ A + GAD I V + P Sbjct: 141 TRPERIGYIRDRLKEGIKILAPGIGAQGGK--------AKDAVKAGADYIIVGRAIYNAP 192 Query: 119 WTKDILINFLKEV 131 ++ E+ Sbjct: 193 NPREAAKAIYDEI 205 >4QDI-A nrPDB Length = 472 Score = 27.7 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 27/79 (34%), Gaps = 8/79 (10%) Query: 20 TENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLD 79 + N + + L+++ G+K + V G GE S E + + D + Sbjct: 346 DDTYNANPTSMRAAAQVLLQQNGIK-VMVMGDIGELGDSSWQEHHDLGRDLAELPLDHIV 404 Query: 80 QV-------IIHVGALSLK 91 V + G S K Sbjct: 405 AVGQFASAALEGAGLHSTK 423 >5UJU-A nrPDB Length = 576 Score = 27.7 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 22/81 (27%) Query: 156 EELLDGILDKIPTFQGLKFSDTDLLDFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGA 215 E+ I + L G+ ++ + D+ + +A G Sbjct: 450 EKFTQEWFGPISFVIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGG 509 Query: 216 VGSTYNYLGKKTNQMLEAFEQ 236 V + N G AF Sbjct: 510 VALSINLTGGVFVNQSAAFSD 530 >2FSI-A nrPDB Length = 853 Score = 27.3 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 21/49 (42%), Gaps = 2/49 (4%) Query: 57 SLSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKE--SQELAQHAAEI 103 ++ +E+ Q E + + K V++ ++ E S EL + + Sbjct: 420 YMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKH 468 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.134 0.347 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,566,170 Number of Sequences: 36641 Number of extensions: 453894 Number of successful extensions: 2051 Number of sequences better than 10.0: 99 Number of HSP's better than 10.0 without gapping: 103 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 1577 Number of HSP's gapped (non-prelim): 165 length of query: 320 length of database: 10,336,785 effective HSP length: 97 effective length of query: 223 effective length of database: 6,782,608 effective search space: 1512521584 effective search space used: 1512521584 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)