BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BV20 (369 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4LDQ-A nrPDB 745 0.0 2A0U-A nrPDB 289 1e-78 1T9K-A nrPDB 242 2e-64 1T5O-A nrPDB 221 4e-58 6A34-A nrPDB 221 4e-58 2YRF-A nrPDB 217 5e-57 3A9C-A nrPDB 118 5e-27 5YG5-A nrPDB 111 5e-25 1VB5-A nrPDB 76 2e-14 5B04-A nrPDB 72 3e-13 6O85-G nrPDB 67 1e-11 6O85-E nrPDB 66 2e-11 6I3M-A nrPDB 59 4e-09 6O81-C nrPDB 59 5e-09 6JLZ-C nrPDB 49 3e-06 5B04-G nrPDB 38 0.006 4Q60-A nrPDB 32 0.31 6I7T-C nrPDB 32 0.50 4J9X-A nrPDB 30 1.1 6I3M-E nrPDB 30 1.4 3RJM-A nrPDB 30 2.3 1XET-A nrPDB 29 3.1 6IXF-A nrPDB 29 4.0 3A5R-A nrPDB 28 4.8 4JCI-A nrPDB 28 5.2 3TSY-A nrPDB 28 5.4 >4LDQ-A nrPDB Length = 369 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/369 (100%), Positives = 369/369 (100%) Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA Sbjct: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA Sbjct: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT Sbjct: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV Sbjct: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER Sbjct: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR Sbjct: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360 Query: 361 DGTLDGPQM 369 DGTLDGPQM Sbjct: 361 DGTLDGPQM 369 >2A0U-A nrPDB Length = 383 Score = 289 bits (740), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 164/353 (46%), Positives = 221/353 (62%), Gaps = 10/353 (2%) Query: 2 TLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAV 61 TLE+I+Y+ GSL++LDQ LP ++ ++ V +V W AI+ M+VRGAPAIA+ L +AV Sbjct: 17 TLESIKYTPGSLRLLDQRKLPLETVFDDVLTVEDIWSAIKEMRVRGAPAIAVSAALGIAV 76 Query: 62 ELQAGAGGPGLAA---LVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATE 118 Q A L + + F+ F++T+RPTAVN+ RDL + + A E Sbjct: 77 ATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNLFNCLRDLKAQVDKLDPTKAAAE 136 Query: 119 EAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSG-GKVTVLTHCNTGALATAG 177 V + + E + D+ N I GA H+L G KV++LT CNTGALAT+ Sbjct: 137 --VAQAFVELAEAVYTNDVAFNEGIMRHGAAHILAAAKAEGRDKVSILTICNTGALATSR 194 Query: 178 YGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAH 237 YGTALGV+R L G+LE + ETRP+NQGARLT +E V E IP TLI D ++ M + Sbjct: 195 YGTALGVVRQLFYDGKLERVYACETRPWNQGARLTVYECVQEDIPCTLICDGAASSLMLN 254 Query: 238 RGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIII 297 R + AVVVGADR+ NGDTANK+GTY LA+ AK HG+ YVAAP+++ D++ +G + I Sbjct: 255 RKIDAVVVGADRICQNGDTANKIGTYNLAVSAKFHGVKLYVAAPTTTLDVKTASGNHVEI 314 Query: 298 EERPGQELTD--VNGVRIAA--PGIGVWNPAFDVTPHDLITGGIITELGVFAP 346 EER E+T V R+ A P + +WNP FD+TP +LITGGIITE GV AP Sbjct: 315 EEREPTEITTNLVTKQRVVADGPHLSIWNPVFDITPSELITGGIITEKGVQAP 367 >1T9K-A nrPDB Length = 347 Score = 242 bits (617), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 149/346 (43%), Positives = 198/346 (57%), Gaps = 17/346 (4%) Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 + + + +S SL++LDQ LP Y + + AI+ M VRGAPAI + Sbjct: 5 LKTKTMEWSGNSLKLLDQRKLPFIEEYVECKTHEEVAHAIKEMIVRGAPAIGVAAAFGYV 64 Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 + L+ G +L +++ L RPTAVN+ A + V A+RE E Sbjct: 65 LGLRDYKTG----SLTDWMKQVKETLARTRPTAVNLFWALNRMEKVFFENADRENLFEIL 120 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 E + M +D+ N++IG GA+ + + T+LTHCN GALAT YGT Sbjct: 121 ENEAL-----KMAYEDIEVNKAIGKNGAQLIKD-------GSTILTHCNAGALATVDYGT 168 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 ALGVIR+ G+ F ETRPY QGARLTA+EL+ + I +ITD+M M + Sbjct: 169 ALGVIRAAVESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKRGLI 228 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 AVVVGADR+ NGDTANK+GTY LA++AK + IPFYVAAP S+ D + +G+EI IEER Sbjct: 229 DAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEER 288 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAP 346 +E+T G RIA G+ V NPAFDVT + LIT IITE GV P Sbjct: 289 RPEEVTHCGGNRIAPEGVKVLNPAFDVTENTLIT-AIITEKGVIRP 333 >1T5O-A nrPDB Length = 351 Score = 221 bits (563), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 140/346 (40%), Positives = 199/346 (57%), Gaps = 17/346 (4%) Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 M+L +I + G L+++DQ LP++ +V + +AI+ + VRGAPA+ G +A Sbjct: 1 MSLRSIFWDDG-LKLIDQTKLPEKLEVIECRNVEELADAIKKLAVRGAPALEAAGAYGIA 59 Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 + + + L ++ FL + RPTAVN+ + A + G + E Sbjct: 60 LAAREREFA-DVDELKEHLKKAADFLASTRPTAVNLFVGIERALNAALK-----GESVEE 113 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 V+E + E + E+D+ NR +G+ GA LLE G V VLT+CN G LAT +GT Sbjct: 114 VKELALREAEKLAEEDVERNRKMGEYGA-ELLE-----DGDV-VLTYCNAGRLATVDWGT 166 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 ALGV+RS G+ ETRP NQG+RLT +EL+ + I TLITDSMV M V Sbjct: 167 ALGVVRSAVEQGKEIRVIACETRPLNQGSRLTCWELMEDGIDVTLITDSMVGIVMQKGMV 226 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 V+VGADR+V + NK+GTY +++VAKHH IPFYVAAP ++ D T K+++IEER Sbjct: 227 DKVIVGADRIVRDA-VFNKIGTYTVSVVAKHHNIPFYVAAPKATFDWE-RTAKDVVIEER 284 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAP 346 P +EL +IA + V+NPAFD TP + +T +ITE GV P Sbjct: 285 PREELIFCGKRQIAPLNVKVYNPAFDPTPLENVT-ALITEYGVIYP 329 >6A34-A nrPDB Length = 364 Score = 221 bits (563), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 139/341 (40%), Positives = 193/341 (56%), Gaps = 14/341 (4%) Query: 6 IRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQA 65 + Y S+ +++Q LLPK+ + E V + EAI+ M VRGAPAI LA+ + Sbjct: 17 VEYKNKSVYMINQRLLPKEFKVEKFSKVEEVAEAIKNMTVRGAPAIGAAAGFGLALYAET 76 Query: 66 GAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERV 125 L F + L RPTAVN+ A + + E E +E ++ + Sbjct: 77 SKAKTKEEFLDGFEK-AYEILKNTRPTAVNLFWALNRIKKLV--EEHSEDPLDE-IKRLI 132 Query: 126 ICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVI 185 + + ++D+ N +G GA V P G +LTHCN G+LAT GT V+ Sbjct: 133 VQEAYKIADEDVEANLRMGHYGAE-----VLPEGN---ILTHCNAGSLATVHLGTVGSVV 184 Query: 186 RSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVV 245 R +H G L+ + ETRP QGARL+A+E Y+ + LI D+ A M V A++V Sbjct: 185 RVMHKDGSLKLLWLDETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQGFVDAIIV 244 Query: 246 GADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQEL 305 GADR+VANGD ANK+GTY LA++A+ HGIPF+ AP SS D+ L++GK+I IEER +E+ Sbjct: 245 GADRIVANGDFANKIGTYMLAVLAREHGIPFFAVAPLSSIDMELKSGKDIPIEERSPEEV 304 Query: 306 TDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAP 346 G RIA P + V+NPAFDVTPH +T GIIT+ GV P Sbjct: 305 LTCGGCRIA-PDVPVYNPAFDVTPHKYLT-GIITDRGVVWP 343 >2YRF-A nrPDB Length = 374 Score = 217 bits (553), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 137/345 (39%), Positives = 195/345 (56%), Gaps = 24/345 (6%) Query: 5 AIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQ 64 ++ + ++ IL+Q LP ++ Y + + ++AI +KVRGAPAI + LA+ Sbjct: 31 SVEWKETAITILNQQKLPDETEYLELTTKEDVFDAIVTLKVRGAPAIGITAAFGLAL--- 87 Query: 65 AGAGGPGLAALVAFVR---DKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAV 121 A + F R D +L ++RPTA+N++ A L+ A V Sbjct: 88 -AAKDIETDNVTEFRRRLEDIKQYLNSSRPTAINLSWALERLSHSVENAISVNEAKTNLV 146 Query: 122 RERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTA 181 E + ED R IG A L ++ G ++ +T CN G++AT+ YGTA Sbjct: 147 HEAIQIQVEDE-----ETCRLIGQ-NALQLFKK----GDRI--MTICNAGSIATSRYGTA 194 Query: 182 LG--VIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRG 239 L + LG H + ETRP QG+RLTA+EL+ I TLITDSM A M + Sbjct: 195 LAPFYLAKQKDLGL--HIYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQ 252 Query: 240 VSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEE 299 +SAV+VGADR+ NGDTANK+GTY LAI+A IPF+VAAP S+ D +++ G +I IEE Sbjct: 253 ISAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEE 312 Query: 300 RPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVF 344 R +E+ ++GVR A + V+NPAFD+TPHDLI+ GIITE G+ Sbjct: 313 RDPEEVRQISGVRTAPSNVPVFNPAFDITPHDLIS-GIITEKGIM 356 >3A9C-A nrPDB Length = 338 Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 95/310 (30%), Positives = 147/310 (47%), Gaps = 23/310 (7%) Query: 38 EAIRAMKVRGAPAIALVGCLSLAVELQA-GAGGPGLAALVAFVRDKLSFLVTARPTAVNM 96 E I+ M++RGA IA +L +LQA + + ++ L RPTAV++ Sbjct: 28 EKIKNMEIRGAGKIARSAAYAL--QLQAEKSKATNVDEFWKEMKQAAKILFETRPTAVSL 85 Query: 97 ARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVA 156 A R + + A GA E +R +I ++ + + IG+ GA+ + Sbjct: 86 PNALRYVMH-RGKIAYSSGADLEQLRFVIINAAKEFIHNSEKALERIGEFGAKRI----- 139 Query: 157 PSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFEL 216 G V ++THC++ A A+ V+++ G+ TETRP QG ++TA EL Sbjct: 140 -EDGDV-IMTHCHSKA--------AISVMKTAWEQGKDIKVIVTETRPKWQG-KITAKEL 188 Query: 217 VYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPF 276 IP + DS AA + VV+GAD + NG NK+GT +A+ AK H + Sbjct: 189 ASYGIPVIYVVDS--AARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTAKEHRVWT 246 Query: 277 YVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGG 336 +AA + G+ + IE R E+ + ++ I VWNPAFDVTP + + Sbjct: 247 MIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNPAFDVTPPEYV-DV 305 Query: 337 IITELGVFAP 346 IITE G+ P Sbjct: 306 IITERGIIPP 315 >5YG5-A nrPDB Length = 324 Score = 111 bits (278), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 86/263 (32%), Positives = 125/263 (47%), Gaps = 20/263 (7%) Query: 84 SFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSI 143 L RPTAV++ A R + + A GA E +R I ++ + + I Sbjct: 59 KILYNTRPTAVSLPNALRYVMH-RVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERI 117 Query: 144 GDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETR 203 G++GA+ + G + ++THC++ A A+ V++ G+ TETR Sbjct: 118 GEIGAKRI------EDGDI-IMTHCHSKA--------AISVMKKAFEQGKNIKVIVTETR 162 Query: 204 PYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTY 263 P QG ++TA EL IP I DS AA + VV+GAD + ANG NK+GT Sbjct: 163 PKWQG-KITAKELASYGIPVIYIVDS--AARHYMKMTDKVVMGADSITANGAVINKIGTS 219 Query: 264 QLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNP 323 +A+ AK H + +AA + G+ + IE R E+ +R I VWNP Sbjct: 220 LIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNP 279 Query: 324 AFDVTPHDLITGGIITELGVFAP 346 AFDVTP + I IITE G+ P Sbjct: 280 AFDVTPPEYI-DVIITERGIIPP 301 >1VB5-A nrPDB Length = 276 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 59/168 (35%), Positives = 84/168 (50%), Gaps = 16/168 (9%) Query: 179 GTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHR 238 T L +IR+ + TE+ P +G L A EL + I +ITD+ + + R Sbjct: 120 STVLEIIRTAKERKKRFKVILTESSPDYEGLHL-ARELEFSGIEFEVITDAQMG--LFCR 176 Query: 239 GVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIE 298 S +VGAD + +G NK GTY LA+ + IPFYVAA + L++G +++E Sbjct: 177 EASIAIVGADMITKDGYVVNKAGTYLLALACHENAIPFYVAAETYKFHPTLKSGDVMLME 236 Query: 299 ERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAP 346 ++L N VRI N FDVTP + GIITELG+ P Sbjct: 237 ----RDLIRGN-VRIR-------NVLFDVTPWKYVR-GIITELGIVIP 271 >5B04-A nrPDB Length = 341 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 55/167 (32%), Positives = 77/167 (46%), Gaps = 27/167 (16%) Query: 198 FCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTA 257 F TE+RP G +T L IP ++ DS V+ M V V+VGA+ VV NG Sbjct: 165 FVTESRPSGSGCLMTR-TLKNACIPTCMVLDSAVSFTMNR--VDLVLVGAEGVVENGGLI 221 Query: 258 NKVGTYQLAIVAKHHGIPFYVAA---------PSSSCDLRLETGKEIIIEERPGQELTDV 308 N++GT+QLA+ AKH PFY A P S D+ + I+ + P E Sbjct: 222 NQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIPF--SRPILEFDDPSPETVHP 279 Query: 309 NGVRIAAPGIGVW------------NPAFDVTPHDLITGGIITELGV 343 I P + NP DVTP + ++ G+IT+LG+ Sbjct: 280 EPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVS-GLITDLGI 325 >6O85-G nrPDB Length = 305 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 59/202 (29%), Positives = 97/202 (48%), Gaps = 14/202 (6%) Query: 151 LLERVAPSGGKVTVLTHC---NTGALATAGYG-TALGVIRSLHSLGRLEHAFCTETRPYN 206 L R++ S K+ L H + + T Y L V+ + + + + TE++P Sbjct: 100 FLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDL 159 Query: 207 QGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLA 266 G ++ A L + +P T++ D+ V M + V+VGA+ VV NG NK+GT Q+A Sbjct: 160 SGKKM-AKALCHLNVPVTVVLDAAVGYIMEKADL--VIVGAEGVVENGGIINKIGTNQMA 216 Query: 267 IVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPG--IGVWNPA 324 + AK PFYV A S +RL + ++ P + + +++A G + +P Sbjct: 217 VCAKAQNKPFYVVAESFKF-VRLFPLNQ---QDVPDKFKYKADTLKVAQTGQDLKEEHPW 272 Query: 325 FDVTPHDLITGGIITELGVFAP 346 D T LIT + T+LGV P Sbjct: 273 VDYTAPSLIT-LLFTDLGVLTP 293 >6O85-E nrPDB Length = 523 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 70/289 (24%), Positives = 130/289 (44%), Gaps = 52/289 (17%) Query: 75 LVAFVRDKLSFLVTARPTAVNMARA----ARDLADVAAREAEREGATE------EAVRER 124 LV ++ +SFL RP + +M A +++ V + + E E +E V+E+ Sbjct: 252 LVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEK 311 Query: 125 VICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGV 184 ++ + + +R +++ S G V ++ C++ + Sbjct: 312 IVLAAQAI---------------SRFAYQKI--SNGDVILVYGCSS---------LVSRI 345 Query: 185 IRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVV 244 ++ + GR ++RP+ +G R T LV+ +PA+ + + AA+ VS V+ Sbjct: 346 LQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASYVLPEVSKVL 402 Query: 245 VGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQE 304 +GA ++ANG ++VGT QLA+VA+ H +P V + R++T + E + Sbjct: 403 LGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDD 462 Query: 305 LTDVNGVRIAAPGIGVW---------NPAFDVTPHDLITGGIITELGVF 344 L G +A + W N +DVTP +L+ +ITELG+ Sbjct: 463 LQCKRGEHVA---LANWQNHASLRLLNLVYDVTPPELV-DLVITELGMI 507 >6I3M-A nrPDB Length = 305 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 59/181 (32%), Positives = 81/181 (44%), Gaps = 29/181 (16%) Query: 177 GYGTALGVIRSLHSLGRLEHAFC--TETRPYNQGARLTAFELVYEQIPATLITDSMVAAA 234 GY A+ + + H+ + C TE+RP QG +L L + IP TLI DS V A Sbjct: 130 GYSRAVFSLLN-HAANKFIRFRCVVTESRPSKQGNQLYTL-LEQKGIPVTLIVDSAVGAV 187 Query: 235 MAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAA---------PSSSC 285 + V V VGA+ V +G N VGTY + ++A + PFYV P SS Sbjct: 188 IDK--VDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSD 245 Query: 286 DLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFA 345 DL + G + R +L D + P D T + IT +IT+LGV Sbjct: 246 DLPM-AGPPLDFTRR-TDDLED-----------ALRGPTIDYTAQEYIT-ALITDLGVLT 291 Query: 346 P 346 P Sbjct: 292 P 292 >6O81-C nrPDB Length = 368 Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 6/201 (2%) Query: 165 LTHCNTG-ALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPA 223 L H ++ + T G+ + + R H E P+ QG + A L I Sbjct: 173 LEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIET 231 Query: 224 TLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSS 283 T++TD+ + A M+ V+ V++G ++ANG GT+ LA+ AKHH P V AP Sbjct: 232 TVMTDAAIFAVMSR--VNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMF 289 Query: 284 SCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGV 343 + ++ + +E+ I + V P FD P +LIT I+ +G Sbjct: 290 KLSPQFPNEEDSFHKFVAPEEVLPFTEGDILE-KVSVHCPVFDYVPPELIT-LFISNIGG 347 Query: 344 FAPEELRTALTTTISSRDGTL 364 AP + ++ D L Sbjct: 348 NAPSYIYRLMSELYHPDDHVL 368 >6JLZ-C nrPDB Length = 399 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 17/171 (9%) Query: 201 ETRPYNQ-GARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANK 259 E P NQ G+ A L I T+I+D+ + A M+ V+ V++G ++ NG Sbjct: 239 EGFPNNQKGSHAMAKRLAQAGIDTTVISDATIFAIMSR--VNKVILGTHAILGNGGLVTY 296 Query: 260 VGTYQLAIVAKHHGIP------FYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRI 313 G +A A+HH P Y +P DL + II P + ++ G I Sbjct: 297 SGAQLVAQAARHHATPVVVCSGIYKLSPVYPYDL-----ESIIQLSSPDKIMSFNEGDLI 351 Query: 314 AAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTL 364 + I NP +D P DL+ IT LG + P L + T + D L Sbjct: 352 SRAEI--LNPYYDYIPPDLV-DLFITNLGGYPPSYLYRIMNDTYDASDTIL 399 >5B04-G nrPDB Length = 467 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 61/293 (20%), Positives = 118/293 (40%), Gaps = 55/293 (18%) Query: 75 LVAFVRDKLSFLVTARPTAVNMARAAR-----------DLADVAAREAEREGATEEAVRE 123 L + ++++LV+ RP +++M A R DL D +E E + +R+ Sbjct: 190 LTTHINSQIAYLVSTRPLSISMGNAIRFLKLEISVLDIDLTDDEGKELLLE-KIDSYIRD 248 Query: 124 RVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALG 183 R+I G + + E++ G V +LT+ ++ T Sbjct: 249 RIIIA---------------GQVIVQAATEKI--QDGDV-ILTYLHSS--------TVND 282 Query: 184 VIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAV 243 V+ ++G+ ++RP +G R+ L I T + S ++ M + V+ + Sbjct: 283 VLIHAKNVGKKFRVVVVDSRPEFEG-RVCLKLLTEHGIECTYVMISALSYIM--QEVTKI 339 Query: 244 VVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQ 303 +G +++NG ++ GT ++++ +P S R++ + E PG Sbjct: 340 FLGGHAMLSNGALYSRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGD 399 Query: 304 ELTDVNGVRIAAPGIGV---WNPA---------FDVTPHDLITGGIITELGVF 344 +L ++ GV GV W +DVTP LIT + E+G+ Sbjct: 400 QLVNM-GVDDFEEKPGVLANWKSVKNLKLLSLKYDVTPPRLIT-VCVCEMGLL 450 >4Q60-A nrPDB Length = 332 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 2/44 (4%) Query: 151 LLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRL 194 L E V+P V+ N+G L G+GT +GV+R+LH +GR+ Sbjct: 86 LCEPVSPDA-AAGVIFFNNSGYLGMCGHGT-IGVVRTLHHMGRI 127 >6I7T-C nrPDB Length = 651 Score = 32.0 bits (71), Expect = 0.50, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 240 VSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEE 299 V V +GA +++NG ++ GT LA+ AK IP V C L+ + + ++ Sbjct: 467 VDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLV------CCESLKFSQRVQLDS 520 Query: 300 RPGQELTDVNGV 311 EL D N + Sbjct: 521 VTFNELADPNDL 532 >4J9X-A nrPDB Length = 332 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 23/34 (67%), Gaps = 1/34 (2%) Query: 164 VLTHCNTGALATAGYGTALGVIRSLHSLGRLEHA 197 V+ N+G L G+GT +G++RSL+ LGR++ Sbjct: 98 VIFFNNSGYLGMCGHGT-IGLVRSLYHLGRIDQG 130 >6I3M-E nrPDB Length = 381 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 75/335 (22%), Positives = 125/335 (37%), Gaps = 52/335 (15%) Query: 40 IRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARA 99 ++ +V+G+ AIAL L L + + A + L+ +RD + L A PTA + Sbjct: 29 LKRRQVQGSYAIAL-ETLQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGNV 87 Query: 100 ARDLADVAAREAEREGATEEAVR----ERVICCTEDMLEKDLR----------------- 138 R + V E E + + E +I ++L+K + Sbjct: 88 IRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGSSSMKTK 147 Query: 139 -DNRSIGDLGARHLLERVAPSGGKVTV----LTHCNTGALA-TAGYGTALG-VIRSLHSL 191 D R + G + L++ + + L H + L T T L +I + Sbjct: 148 TDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLITARERS 207 Query: 192 GRLEHAFCTETRPYN-QGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRV 250 R TE P N + A A +L I ++ DS V A M+ G V++G V Sbjct: 208 NRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSRVG--KVIIGTKAV 265 Query: 251 VANGDT-ANKVGTYQLAIVAKHHGIP------FYVAAPSSSCDLR--LETG--KEIIIEE 299 NG T ++ G + A+ P Y +P D+ +E G + I+ Sbjct: 266 FVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRM 325 Query: 300 RPGQELTDVNGVRIAAP---------GIGVWNPAF 325 P + L VN + P +G +NP+F Sbjct: 326 DPRKRLDTVNQITDYVPPENIDIYITNVGGFNPSF 360 >3RJM-A nrPDB Length = 169 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 6/58 (10%) Query: 191 LGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGAD 248 LG H C +T Q +L F Q+PA +TDS + A ++H GV + G D Sbjct: 72 LGYDVHVLCDQTAQEMQ-EKLQNFA----QLPAHRVTDSCIVALLSH-GVEGAIYGVD 123 >1XET-A nrPDB Length = 413 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 45/185 (24%), Positives = 74/185 (40%), Gaps = 41/185 (22%) Query: 102 DLADVAAREAEREGATEEAVRERVICCTEDMLEK--DLRDNRSIGDLGARHLL------- 152 +L D R ER A+++R + TE++L+K D+ + L AR + Sbjct: 73 ELKDKFKRICERS-----AIKQRYMYLTEEILKKNPDVCAFVEVPSLDARQAMLAMEVPR 127 Query: 153 ----------ERVAPSGGKVTVLTHCNTGA--LATAGYGTA--LGVIRSLHSLGRLEHA- 197 + S +T L C+T L A + A LG+ S+ +G +H Sbjct: 128 LAKEAAEKAIQEWGQSKSGITHLIFCSTTTPDLPGADFEVAKLLGLHPSVKRVGVFQHGC 187 Query: 198 --------FCTETRPYNQGARLTAF----ELVYEQIPATLITDSMVAAAMAHRGVSAVVV 245 + N+GAR+ V + P+ DS+V A+ G SA++V Sbjct: 188 FAGGTVLRMAKDLAENNRGARVLVICSETTAVTFRGPSETHLDSLVGQALFGDGASALIV 247 Query: 246 GADRV 250 GAD + Sbjct: 248 GADPI 252 >6IXF-A nrPDB Length = 228 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 9/115 (7%) Query: 93 AVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLL 152 A +AR A+ A A ++ +R A +E + + +LE D R S H Sbjct: 66 ARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHAT 125 Query: 153 ERVAPSGGKVT--VLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPY 205 +RVA + T L H T A Y A+G +R L +L+ A +++PY Sbjct: 126 QRVAEAEQTKTRSELVHKETA----ARYNAAMGRMRQLE--KKLKRA-INKSKPY 173 >3A5R-A nrPDB Length = 387 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 51/223 (22%), Positives = 82/223 (36%), Gaps = 24/223 (10%) Query: 49 PAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAA 108 P +A LA + G P A D F VT +N+ + + L + + Sbjct: 2 PGMATEEMKKLATVMAIGTANPPNCYYQADFPD-FYFRVTNSDHLINLKQKFKRLCENSR 60 Query: 109 REAEREGATEEAVRERVICCTEDMLEKDLRDN---RSIGDLGARHLLERVAPSG---GKV 162 E TEE ++E + ++R + + +LG L+ + G K+ Sbjct: 61 IEKRYLHVTEEILKENPNIAAYEATSLNVRHKMQVKGVAELGKEAALKAIKEWGQPKSKI 120 Query: 163 TVLTHCNTGALATAGYGTALGVIRSLH-SLGRL--EHAFC----------TETRPYNQGA 209 T L C + G L + L S+ R H C + N+GA Sbjct: 121 THLIVCCLAGVDMPGADYQLTKLLDLDPSVKRFMFYHLGCYAGGTVLRLAKDIAENNKGA 180 Query: 210 R--LTAFELVYEQI--PATLITDSMVAAAMAHRGVSAVVVGAD 248 R + E+ P+ DSM+ A+ G +AV+VGAD Sbjct: 181 RVLIVCSEMTTTCFRGPSETHLDSMIGQAILGDGAAAVIVGAD 223 >4JCI-A nrPDB Length = 333 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 1/37 (2%) Query: 158 SGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRL 194 S V+ N+G L G+GT +G++ SLH LG+L Sbjct: 92 SDASCGVIFFNNSGYLGMCGHGT-IGLVASLHHLGQL 127 >3TSY-A nrPDB Length = 979 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 39/163 (23%), Positives = 62/163 (38%), Gaps = 35/163 (21%) Query: 121 VRERVICCTEDMLEK------------DLRDN------RSIGDLGARHLLERVAPSGGKV 162 +++R I TE+MLE+ ++R +G A L+ K+ Sbjct: 652 IKKRYIHLTEEMLEEHPNIGAYMAPSLNIRQEIITAEVPKLGKEAALKALKEWGQPKSKI 711 Query: 163 TVLTHCNTGALATAGYGTALGVIRSLHSLGR---LEHAFC----------TETRPYNQGA 209 T L C T + G L + L R L H C + N GA Sbjct: 712 THLVFCTTSGVEMPGADYKLANLLGLEPSVRRVMLYHQGCYAGGTVLRTAKDLAENNAGA 771 Query: 210 RL----TAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGAD 248 R+ + +V + P+ DS+V A+ G +AV+VG+D Sbjct: 772 RVLVVCSEITVVTFRGPSEDALDSLVGQALFGDGSAAVIVGSD 814 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4LDQ-A nrPDB 468 e-132 1T9K-A nrPDB 400 e-112 2A0U-A nrPDB 386 e-108 1T5O-A nrPDB 381 e-106 6A34-A nrPDB 357 3e-99 2YRF-A nrPDB 356 1e-98 3A9C-A nrPDB 325 2e-89 5YG5-A nrPDB 291 3e-79 6O81-C nrPDB 225 2e-59 6O85-E nrPDB 220 7e-58 6O85-G nrPDB 200 6e-52 6JLZ-C nrPDB 188 2e-48 1VB5-A nrPDB 175 3e-44 5B04-A nrPDB 167 7e-42 6I3M-A nrPDB 160 1e-39 Sequences not found previously or not previously below threshold: 5B04-G nrPDB 131 6e-31 6I3M-E nrPDB 123 1e-28 6I7T-C nrPDB 106 2e-23 5DBO-A nrPDB 78 8e-15 3RFT-A nrPDB 34 0.085 3L12-A nrPDB 31 0.84 6C4N-A nrPDB 30 1.7 2WX2-A nrPDB 30 2.1 6IOZ-A nrPDB 30 2.2 6EOT-A nrPDB 28 7.3 4HDT-A nrPDB 28 7.5 >4LDQ-A nrPDB Length = 369 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 369/369 (100%), Positives = 369/369 (100%) Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA Sbjct: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA Sbjct: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT Sbjct: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV Sbjct: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER Sbjct: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR Sbjct: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360 Query: 361 DGTLDGPQM 369 DGTLDGPQM Sbjct: 361 DGTLDGPQM 369 >1T9K-A nrPDB Length = 347 Score = 400 bits (1028), Expect = e-112, Method: Composition-based stats. Identities = 149/348 (42%), Positives = 197/348 (56%), Gaps = 17/348 (4%) Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 + + + +S SL++LDQ LP Y + + AI+ M VRGAPAI + Sbjct: 5 LKTKTMEWSGNSLKLLDQRKLPFIEEYVECKTHEEVAHAIKEMIVRGAPAIGVAAAFGYV 64 Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 + L+ G +L +++ L RPTAVN+ A + V A+RE E Sbjct: 65 LGLRDYKTG----SLTDWMKQVKETLARTRPTAVNLFWALNRMEKVFFENADRENLFEIL 120 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 E + M +D+ N++IG GA+ + T+LTHCN GALAT YGT Sbjct: 121 ENEAL-----KMAYEDIEVNKAIGKNGAQLIK-------DGSTILTHCNAGALATVDYGT 168 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 ALGVIR+ G+ F ETRPY QGARLTA+EL+ + I +ITD+M M + Sbjct: 169 ALGVIRAAVESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKRGLI 228 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 AVVVGADR+ NGDTANK+GTY LA++AK + IPFYVAAP S+ D + +G+EI IEER Sbjct: 229 DAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEER 288 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEE 348 +E+T G RIA G+ V NPAFDVT + LIT IITE GV P Sbjct: 289 RPEEVTHCGGNRIAPEGVKVLNPAFDVTENTLIT-AIITEKGVIRPPF 335 >2A0U-A nrPDB Length = 383 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 163/354 (46%), Positives = 219/354 (61%), Gaps = 10/354 (2%) Query: 2 TLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAV 61 TLE+I+Y+ GSL++LDQ LP ++ ++ V +V W AI+ M+VRGAPAIA+ L +AV Sbjct: 17 TLESIKYTPGSLRLLDQRKLPLETVFDDVLTVEDIWSAIKEMRVRGAPAIAVSAALGIAV 76 Query: 62 ELQAGAGGPGLA---ALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATE 118 Q A L + F+ F++T+RPTAVN+ RDL + + A E Sbjct: 77 ATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNLFNCLRDLKAQVDKLDPTKAAAE 136 Query: 119 EAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSG-GKVTVLTHCNTGALATAG 177 V + + E + D+ N I GA H+L G KV++LT CNTGALAT+ Sbjct: 137 --VAQAFVELAEAVYTNDVAFNEGIMRHGAAHILAAAKAEGRDKVSILTICNTGALATSR 194 Query: 178 YGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAH 237 YGTALGV+R L G+LE + ETRP+NQGARLT +E V E IP TLI D ++ M + Sbjct: 195 YGTALGVVRQLFYDGKLERVYACETRPWNQGARLTVYECVQEDIPCTLICDGAASSLMLN 254 Query: 238 RGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIII 297 R + AVVVGADR+ NGDTANK+GTY LA+ AK HG+ YVAAP+++ D++ +G + I Sbjct: 255 RKIDAVVVGADRICQNGDTANKIGTYNLAVSAKFHGVKLYVAAPTTTLDVKTASGNHVEI 314 Query: 298 EERPGQELTDV--NGVRIAA--PGIGVWNPAFDVTPHDLITGGIITELGVFAPE 347 EER E+T R+ A P + +WNP FD+TP +LITGGIITE GV AP Sbjct: 315 EEREPTEITTNLVTKQRVVADGPHLSIWNPVFDITPSELITGGIITEKGVQAPA 368 >1T5O-A nrPDB Length = 351 Score = 381 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 138/348 (39%), Positives = 197/348 (56%), Gaps = 17/348 (4%) Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60 M+L +I + G L+++DQ LP++ +V + +AI+ + VRGAPA+ G +A Sbjct: 1 MSLRSIFWDDG-LKLIDQTKLPEKLEVIECRNVEELADAIKKLAVRGAPALEAAGAYGIA 59 Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 + + + L ++ FL + RPTAVN+ + A + G + E Sbjct: 60 LAAREREFA-DVDELKEHLKKAADFLASTRPTAVNLFVGIERALNAALK-----GESVEE 113 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 V+E + E + E+D+ NR +G+ GA L G V VLT+CN G LAT +GT Sbjct: 114 VKELALREAEKLAEEDVERNRKMGEYGAELL------EDGDV-VLTYCNAGRLATVDWGT 166 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 ALGV+RS G+ ETRP NQG+RLT +EL+ + I TLITDSMV M V Sbjct: 167 ALGVVRSAVEQGKEIRVIACETRPLNQGSRLTCWELMEDGIDVTLITDSMVGIVMQKGMV 226 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 V+VGADR+V + NK+GTY +++VAKHH IPFYVAAP ++ D T K+++IEER Sbjct: 227 DKVIVGADRIVRD-AVFNKIGTYTVSVVAKHHNIPFYVAAPKATFDWE-RTAKDVVIEER 284 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEE 348 P +EL +IA + V+NPAFD TP + +T +ITE GV P Sbjct: 285 PREELIFCGKRQIAPLNVKVYNPAFDPTPLENVT-ALITEYGVIYPPY 331 >6A34-A nrPDB Length = 364 Score = 357 bits (917), Expect = 3e-99, Method: Composition-based stats. Identities = 139/349 (39%), Positives = 193/349 (55%), Gaps = 14/349 (4%) Query: 4 EAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVEL 63 + Y S+ +++Q LLPK+ + E V + EAI+ M VRGAPAI LA+ Sbjct: 15 RTVEYKNKSVYMINQRLLPKEFKVEKFSKVEEVAEAIKNMTVRGAPAIGAAAGFGLALYA 74 Query: 64 QAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRE 123 + L F + L RPTAVN+ A + + E E +E ++ Sbjct: 75 ETSKAKTKEEFLDGFEK-AYEILKNTRPTAVNLFWALNRIKKLV--EEHSEDPLDE-IKR 130 Query: 124 RVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALG 183 ++ + ++D+ N +G GA V P G +LTHCN G+LAT GT Sbjct: 131 LIVQEAYKIADEDVEANLRMGHYGAE-----VLPEGN---ILTHCNAGSLATVHLGTVGS 182 Query: 184 VIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAV 243 V+R +H G L+ + ETRP QGARL+A+E Y+ + LI D+ A M V A+ Sbjct: 183 VVRVMHKDGSLKLLWLDETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQGFVDAI 242 Query: 244 VVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQ 303 +VGADR+VANGD ANK+GTY LA++A+ HGIPF+ AP SS D+ L++GK+I IEER + Sbjct: 243 IVGADRIVANGDFANKIGTYMLAVLAREHGIPFFAVAPLSSIDMELKSGKDIPIEERSPE 302 Query: 304 ELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTA 352 E+ G RIA + V+NPAFDVTPH +T GIIT+ GV P R Sbjct: 303 EVLTCGGCRIAP-DVPVYNPAFDVTPHKYLT-GIITDRGVVWPPFKRNL 349 >2YRF-A nrPDB Length = 374 Score = 356 bits (912), Expect = 1e-98, Method: Composition-based stats. Identities = 132/348 (37%), Positives = 188/348 (54%), Gaps = 20/348 (5%) Query: 4 EAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVEL 63 ++ + ++ IL+Q LP ++ Y + + ++AI +KVRGAPAI + LA+ Sbjct: 30 RSVEWKETAITILNQQKLPDETEYLELTTKEDVFDAIVTLKVRGAPAIGITAAFGLALA- 88 Query: 64 QAGAGGPGLAALVAFVR---DKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120 A + F R D +L ++RPTA+N++ A L+ A Sbjct: 89 ---AKDIETDNVTEFRRRLEDIKQYLNSSRPTAINLSWALERLSHSVENAISVNEAKTNL 145 Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180 V E + E D R IG + + ++T CN G++AT+ YGT Sbjct: 146 VHEAIQIQVE-----DEETCRLIGQNALQLFKKGDR-------IMTICNAGSIATSRYGT 193 Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240 AL H + ETRP QG+RLTA+EL+ I TLITDSM A M + + Sbjct: 194 ALAPFYLAKQKDLGLHIYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQI 253 Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300 SAV+VGADR+ NGDTANK+GTY LAI+A IPF+VAAP S+ D +++ G +I IEER Sbjct: 254 SAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEER 313 Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEE 348 +E+ ++GVR A + V+NPAFD+TPHDLI+ GIITE G+ Sbjct: 314 DPEEVRQISGVRTAPSNVPVFNPAFDITPHDLIS-GIITEKGIMTGNY 360 >3A9C-A nrPDB Length = 338 Score = 325 bits (832), Expect = 2e-89, Method: Composition-based stats. Identities = 93/317 (29%), Positives = 148/317 (46%), Gaps = 21/317 (6%) Query: 30 VGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTA 89 V V + E I+ M++RGA IA +L ++ + + + ++ L Sbjct: 20 VKEVLEIAEKIKNMEIRGAGKIARSAAYALQLQAE-KSKATNVDEFWKEMKQAAKILFET 78 Query: 90 RPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGAR 149 RPTAV++ A R + + A GA E +R +I ++ + + IG+ GA+ Sbjct: 79 RPTAVSLPNALRYVMH-RGKIAYSSGADLEQLRFVIINAAKEFIHNSEKALERIGEFGAK 137 Query: 150 HLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGA 209 + G V ++THC++ A A+ V+++ G+ TETRP QG Sbjct: 138 RI------EDGDV-IMTHCHSKA--------AISVMKTAWEQGKDIKVIVTETRPKWQG- 181 Query: 210 RLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVA 269 ++TA EL IP + DS A + VV+GAD + NG NK+GT +A+ A Sbjct: 182 KITAKELASYGIPVIYVVDSA--ARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTA 239 Query: 270 KHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTP 329 K H + +AA + G+ + IE R E+ + ++ I VWNPAFDVTP Sbjct: 240 KEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNPAFDVTP 299 Query: 330 HDLITGGIITELGVFAP 346 + + IITE G+ P Sbjct: 300 PEYV-DVIITERGIIPP 315 >5YG5-A nrPDB Length = 324 Score = 291 bits (744), Expect = 3e-79, Method: Composition-based stats. Identities = 97/317 (30%), Positives = 149/317 (47%), Gaps = 21/317 (6%) Query: 30 VGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTA 89 V V++ E I++M++RGA IA +L ++ + + L ++ L Sbjct: 6 VKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAE-KSKAKEPEELWNELKVASKILYNT 64 Query: 90 RPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGAR 149 RPTAV++ A R + + A GA E +R I ++ + + IG++GA+ Sbjct: 65 RPTAVSLPNALRYVMH-RVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAK 123 Query: 150 HLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGA 209 + G + ++THC++ A A+ V++ G+ TETRP QG Sbjct: 124 RI------EDGDI-IMTHCHSKA--------AISVMKKAFEQGKNIKVIVTETRPKWQG- 167 Query: 210 RLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVA 269 ++TA EL IP I DS A + VV+GAD + ANG NK+GT +A+ A Sbjct: 168 KITAKELASYGIPVIYIVDSA--ARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTA 225 Query: 270 KHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTP 329 K H + +AA + G+ + IE R E+ +R I VWNPAFDVTP Sbjct: 226 KEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTP 285 Query: 330 HDLITGGIITELGVFAP 346 + I IITE G+ P Sbjct: 286 PEYI-DVIITERGIIPP 301 >6O81-C nrPDB Length = 368 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 68/345 (19%), Positives = 125/345 (36%), Gaps = 20/345 (5%) Query: 34 HQAWEAIRAMKVRGAPAIALVGC---LSLAVELQAGAGGPGLAALVAFVRDKLSFLVTAR 90 + + +K G P + L L ++ L+ +R + + A+ Sbjct: 30 ERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQ 89 Query: 91 PTAVNMARAARDLADVAARE------AEREGATEEAVRERV----ICCTEDMLEKDLRDN 140 P+ + R + + E E +E++ + + + L+ N Sbjct: 90 PSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSN 149 Query: 141 RSIGDLGARHLLERVAPSGGKVTVLTHCNTG-ALATAGYGTALGVIRSLHSLGRLEHAFC 199 I + + L H ++ + T G+ + + R H Sbjct: 150 -IIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIV 208 Query: 200 TETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANK 259 E P+ QG + A L I T++TD+ + A M+ V+ V++G ++ANG Sbjct: 209 AECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--VNKVIIGTKTILANGALRAV 265 Query: 260 VGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIG 319 GT+ LA+ AKHH P V AP + ++ + +E+ I + Sbjct: 266 TGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEK-VS 324 Query: 320 VWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTL 364 V P FD P +LIT I+ +G AP + ++ D L Sbjct: 325 VHCPVFDYVPPELIT-LFISNIGGNAPSYIYRLMSELYHPDDHVL 368 >6O85-E nrPDB Length = 523 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 75/320 (23%), Positives = 140/320 (43%), Gaps = 49/320 (15%) Query: 45 VRGAPAIALVGCLSLAVELQAGAGGPGLA---ALVAFVRDKLSFLVTARPTAVNMARA-- 99 V G+ A + +L +Q P LV ++ +SFL RP + +M A Sbjct: 219 VSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIK 278 Query: 100 --ARDLADVAAREAEREGATE------EAVRERVICCTEDMLEKDLRDNRSIGDLGARHL 151 +++ V + + E E +E V+E+++ + + +R Sbjct: 279 FLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAI---------------SRFA 323 Query: 152 LERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARL 211 +++ S G V ++ C++ +++ + GR ++RP+ +G R Sbjct: 324 YQKI--SNGDVILVYGCSS---------LVSRILQEAWTEGRRFRVVVVDSRPWLEG-RH 371 Query: 212 TAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKH 271 T LV+ +PA+ + + AA+ VS V++GA ++ANG ++VGT QLA+VA+ Sbjct: 372 TLRSLVHAGVPASYLL--IPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARA 429 Query: 272 HGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPG------IGVWNPAF 325 H +P V + R++T + E +L G +A + + N + Sbjct: 430 HNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVY 489 Query: 326 DVTPHDLITGGIITELGVFA 345 DVTP +L+ +ITELG+ Sbjct: 490 DVTPPELV-DLVITELGMIP 508 >6O85-G nrPDB Length = 305 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 79/302 (26%), Positives = 127/302 (42%), Gaps = 23/302 (7%) Query: 67 AGGPGLAALVAFVRDKLSFLVTARPTAV-----NMARAARDLADVAAREAEREGATEEAV 121 P +A+ VA +R L FL + + N+ A L V + A G E + Sbjct: 15 KEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGG-ELFL 73 Query: 122 RERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHC---NTGALATAGY 178 R + E D + I L R++ S K+ L H + + T Y Sbjct: 74 RFISLASLE---YSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAY 130 Query: 179 GTA-LGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAH 237 L V+ + + + + TE++P G ++ A L + +P T++ D+ V M Sbjct: 131 SRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKM-AKALCHLNVPVTVVLDAAVGYIMEK 189 Query: 238 RGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIII 297 V+VGA+ VV NG NK+GT Q+A+ AK PFYV A S +RL + Sbjct: 190 A--DLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKF-VRLFPLNQ--- 243 Query: 298 EERPGQELTDVNGVRIAAPG--IGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTT 355 ++ P + + +++A G + +P D T LIT + T+LGV P + L Sbjct: 244 QDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTAPSLIT-LLFTDLGVLTPSAVSDELIK 302 Query: 356 TI 357 Sbjct: 303 LY 304 >6JLZ-C nrPDB Length = 399 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 51/207 (24%), Positives = 82/207 (39%), Gaps = 8/207 (3%) Query: 161 KVTVLTHCNTG-ALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQ-GARLTAFELVY 218 +V + H ++ + T G + + R E P NQ G+ A L Sbjct: 198 EVQSMDHLHSNEIILTQGCSKTVEAFLRFAAKKRKFSVIVAEGFPNNQKGSHAMAKRLAQ 257 Query: 219 EQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYV 278 I T+I+D+ + A M+ V+ V++G ++ NG G +A A+HH P V Sbjct: 258 AGIDTTVISDATIFAIMSR--VNKVILGTHAILGNGGLVTYSGAQLVAQAARHHATPVVV 315 Query: 279 AAPSSSCDLRLETG-KEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGI 337 + + II P + ++ G I+ I NP +D P DL+ Sbjct: 316 CSGIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISRAEI--LNPYYDYIPPDLV-DLF 372 Query: 338 ITELGVFAPEELRTALTTTISSRDGTL 364 IT LG + P L + T + D L Sbjct: 373 ITNLGGYPPSYLYRIMNDTYDASDTIL 399 >1VB5-A nrPDB Length = 276 Score = 175 bits (444), Expect = 3e-44, Method: Composition-based stats. Identities = 75/316 (23%), Positives = 124/316 (39%), Gaps = 51/316 (16%) Query: 34 HQAWEAIRAMK---VRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTAR 90 + E +R MK ++GA +A G + + A++ + + Sbjct: 4 ERVLEILREMKRERIKGASWLAKKGAEAFLTLAEELDESLLEDAIMELREEVVKV----N 59 Query: 91 PTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARH 150 P+ ++ V R + E +R R + +GA+ Sbjct: 60 PSMASLYN-LARFIPVTNRRDILKSRALEFLRRM------------EEAKRELASIGAQL 106 Query: 151 LLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGAR 210 + G V ++TH + T L +IR+ + TE+ P +G Sbjct: 107 I------DDGDV-IITHSFS--------STVLEIIRTAKERKKRFKVILTESSPDYEGLH 151 Query: 211 LTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAK 270 L A EL + I +ITD+ + + R S +VGAD + +G NK GTY LA+ Sbjct: 152 L-ARELEFSGIEFEVITDAQMG--LFCREASIAIVGADMITKDGYVVNKAGTYLLALACH 208 Query: 271 HHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPH 330 + IPFYVAA + L++G +++E + + + N FDVTP Sbjct: 209 ENAIPFYVAAETYKFHPTLKSGDVMLMERD------------LIRGNVRIRNVLFDVTPW 256 Query: 331 DLITGGIITELGVFAP 346 + GIITELG+ P Sbjct: 257 KYVR-GIITELGIVIP 271 >5B04-A nrPDB Length = 341 Score = 167 bits (422), Expect = 7e-42, Method: Composition-based stats. Identities = 68/313 (21%), Positives = 119/313 (38%), Gaps = 45/313 (14%) Query: 54 VGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAER 113 V + V+L + + ++ + +++ + L ++++ R Sbjct: 37 VAAIEALVQLLSRSQAKTISEFMDILQNGSNTLKEGVQNNISLSAGCDIFQRFVTRSLHD 96 Query: 114 EGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGAL 173 G E + ++ + +++ + I LG + + + Sbjct: 97 VG-DFEQCKRHLVENGKLFIQRARACRQRIAHLGYPLIR----------------DGSVI 139 Query: 174 ATAGYGT-ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVA 232 T G+ V+ + F TE+RP G +T L IP ++ DS V+ Sbjct: 140 LTHGFSRGVAAVLLAAAKRHVRFKVFVTESRPSGSGCLMT-RTLKNACIPTCMVLDSAVS 198 Query: 233 AAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAA---------PSS 283 M V V+VGA+ VV NG N++GT+QLA+ AKH PFY A P S Sbjct: 199 FTMNR--VDLVLVGAEGVVENGGLINQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLS 256 Query: 284 SCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVW------------NPAFDVTPHD 331 D+ + I+ + P E I P + NP DVTP + Sbjct: 257 QYDIPF--SRPILEFDDPSPETVHPEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPE 314 Query: 332 LITGGIITELGVF 344 ++ G+IT+LG+ Sbjct: 315 FVS-GLITDLGII 326 >6I3M-A nrPDB Length = 305 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 65/295 (22%), Positives = 111/295 (37%), Gaps = 28/295 (9%) Query: 55 GCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAERE 114 + V L A ++ ++ L+ + P +V++ R Sbjct: 25 AAIEALVTLLRIKTPETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLY 84 Query: 115 GATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALA 174 G E ++ +I + + + + I ++G + + + ++ Sbjct: 85 G-DWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFI------ADDDIILV--------- 128 Query: 175 TAGYGTALGVIRSLHSLGR--LEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVA 232 GY A+ + + H+ + TE+RP QG +L L + IP TLI DS V Sbjct: 129 -HGYSRAVFSLLN-HAANKFIRFRCVVTESRPSKQGNQLYTL-LEQKGIPVTLIVDSAVG 185 Query: 233 AAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETG 292 A + V V VGA+ V +G N VGTY + ++A + PFYV S Sbjct: 186 AVIDK--VDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLS 243 Query: 293 KEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPE 347 + + P + T R + P D T + IT +IT+LGV P Sbjct: 244 SDDLPMAGPPLDFTR----RTDDLEDALRGPTIDYTAQEYIT-ALITDLGVLTPS 293 >5B04-G nrPDB Length = 467 Score = 131 bits (328), Expect = 6e-31, Method: Composition-based stats. Identities = 52/305 (17%), Positives = 110/305 (36%), Gaps = 35/305 (11%) Query: 64 QAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAAR--DLADVAAREAEREGATEEAV 121 Q G L + ++++LV+ RP +++M A R L + +E + Sbjct: 179 QTPYGTTLSRHLTTHINSQIAYLVSTRPLSISMGNAIRFLKLEISVLDIDLTDDEGKELL 238 Query: 122 RERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTA 181 E++ D I G + +LT+ ++ T Sbjct: 239 LEKI----------DSYIRDRIIIAGQVIVQAATEKIQDGDVILTYLHS--------STV 280 Query: 182 LGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVS 241 V+ ++G+ ++RP +G R+ L I T + S ++ M V+ Sbjct: 281 NDVLIHAKNVGKKFRVVVVDSRPEFEG-RVCLKLLTEHGIECTYVMISALSYIMQ--EVT 337 Query: 242 AVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERP 301 + +G +++NG ++ GT ++++ +P S R++ + E P Sbjct: 338 KIFLGGHAMLSNGALYSRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAP 397 Query: 302 GQELTDVNGVRIAA-----------PGIGVWNPAFDVTPHDLITGGIITELGVFAPEELR 350 G +L ++ + + + +DVTP LIT + E+G+ + Sbjct: 398 GDQLVNMGVDDFEEKPGVLANWKSVKNLKLLSLKYDVTPPRLIT-VCVCEMGLLPSTSVP 456 Query: 351 TALTT 355 + Sbjct: 457 AIINE 461 >6I3M-E nrPDB Length = 381 Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats. Identities = 73/364 (20%), Positives = 118/364 (32%), Gaps = 37/364 (10%) Query: 32 SVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARP 91 ++ ++ +V+G+ AIAL L L + + A + L+ +RD + L A P Sbjct: 21 TIDTFVAKLKRRQVQGSYAIALE-TLQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHP 79 Query: 92 TAVNMARAARDLADVAAREAEREGATE----------------------EAVRERVICCT 129 TA + R + V E E + + E + + Sbjct: 80 TAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSS 139 Query: 130 EDMLEKDLRDNRSIGDLGARHLLERVAPSGGKV----TVLTHCNTGALA-TAGYGTALGV 184 K D R + G + L++ + + L H + L T T L Sbjct: 140 GSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKF 199 Query: 185 IRSLHSL-GRLEHAFCTETRPYN-QGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSA 242 + + R TE P N + A A +L I ++ DS V A M+ V Sbjct: 200 LITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSR--VGK 257 Query: 243 VVVGADRVVANGDTANK-VGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERP 301 V++G V NG T + G + A+ P + A E +E Sbjct: 258 VIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGG 317 Query: 302 GQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRD 361 Q + + N D P + I IT +G F P + D Sbjct: 318 SQRILPRMD---PRKRLDTVNQITDYVPPENI-DIYITNVGGFNPSFIYRIAWDNYKQID 373 Query: 362 GTLD 365 LD Sbjct: 374 VHLD 377 >6I7T-C nrPDB Length = 651 Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 21/248 (8%) Query: 64 QAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAER--EGATEEAV 121 Q G L +++ ++ L ARP +V M A R L + + A ++ + Sbjct: 308 QTPKGTTLSRNLTSYLSHQIDLLKKARPLSVTMGNAIRWLKQEISLIDPSTPDKAAKKDL 367 Query: 122 RERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTA 181 E++ ++ +E ++ I D + + E T++T+ ++ L Sbjct: 368 CEKIGQFAKEKIEL---ADQLIIDNASTQIEEST-------TIVTYGSSKVLTEL----- 412 Query: 182 LGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVS 241 ++ + SL + ++RP +G ++ A L + + + V Sbjct: 413 --LLHNAISLKKNIKVIVVDSRPLFEGRKM-AETLRNAGVNVMYALITSLDTIFNM-DVD 468 Query: 242 AVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERP 301 V +GA +++NG ++ GT LA+ AK IP V S R++ E Sbjct: 469 YVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLDSVTFNELAD 528 Query: 302 GQELTDVN 309 +L +++ Sbjct: 529 PNDLVNID 536 Score = 37.9 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 316 PGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTT 355 P + + N +D+TP + I +ITE G P + L Sbjct: 608 PSLNIVNILYDLTPPEYIKK-VITEFGALPPSSVPVILRE 646 >5DBO-A nrPDB Length = 466 Score = 77.5 bits (189), Expect = 8e-15, Method: Composition-based stats. Identities = 44/273 (16%), Positives = 87/273 (31%), Gaps = 33/273 (12%) Query: 79 VRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLR 138 + ++ +L RP M A R L + E+ +E ++ + ++ + + Sbjct: 209 LNPQIEYLTECRPMCFAMGNAIRLLKAKVNKFDI--NTPEDEAKEGLLEWIDFLINERIT 266 Query: 139 DNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAF 198 + A + + G V + + G+ + Sbjct: 267 LAEYVIARNAAQ-----SINDGDTIVTYG---------RHRLVEKTLLRARKEGKSFNVT 312 Query: 199 CTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTAN 258 + +G L A L + IP + ++ S V +G + + ANG Sbjct: 313 VLDDPYVGEGKEL-AKVLRHAGIPVLY-SPNLGGLRSKVPAASNVFLGGEAIFANGSLHA 370 Query: 259 KVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGI 318 GT +A+ A + G V + + D + + E + Sbjct: 371 PSGTADVAMAATNAGAKVIVLCETINFDRERVSVDALTYNEIDPE-----------RNTG 419 Query: 319 GVWNPAFDVTPHDLITGGIITEL---GVFAPEE 348 + FD T IT G+ITE+ G +P + Sbjct: 420 DCFRLLFDNTHERYIT-GVITEIEFGGGNSPAQ 451 >3RFT-A nrPDB Length = 267 Score = 34.4 bits (77), Expect = 0.085, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 45/140 (32%), Gaps = 27/140 (19%) Query: 240 VSAVVVGADRVVANGDTA-----------NKVGTYQLAIVAKHHGIPFYVAAP---SSSC 285 V+A+V G D +V G + N +G Y L A+ HG P V A + Sbjct: 58 VNAMVAGCDGIVHLGGISVEKPFEQILQGNIIGLYNLYEAARAHGQPRIVFASSNHTIGY 117 Query: 286 DLRL-ETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVF 344 + G ++ ++ G +A FD + +G Sbjct: 118 YPQTERLGPDVPARPDGLYGVSKCFGENLARM-------YFD----KFGQETALVRIGSC 166 Query: 345 APE-ELRTALTTTISSRDGT 363 PE L+T S D Sbjct: 167 TPEPNNYRMLSTWFSHDDFV 186 >3L12-A nrPDB Length = 313 Score = 30.9 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 10/84 (11%) Query: 281 PSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAF-DVTPHDLIT----- 334 P ++ D ++ K + + E +A+ G +W P F DVTP +L+ Sbjct: 212 PENADDPGEDSAKPVGPDYDRMTESLP---QAVASAGGQLWCPYFLDVTP-ELVAEAHDL 267 Query: 335 GGIITELGVFAPEELRTALTTTIS 358 G I+ V PE++R TT + Sbjct: 268 GLIVLTWTVNEPEDIRRMATTGVD 291 >6C4N-A nrPDB Length = 449 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/129 (13%), Positives = 34/129 (26%), Gaps = 10/129 (7%) Query: 105 DVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGG---- 160 + A ++ A + ++ C D+ LG L V+ G Sbjct: 88 NAALDVFHQDPAELRDDWQTLVLCVPADSYLDVVRGLPWERLGGVRTLLLVSAFIGANLL 147 Query: 161 -KVTVLTHCNTGALATAGYGTALGVI-----RSLHSLGRLEHAFCTETRPYNQGARLTAF 214 + + C L+ + Y A VI + + +RP Sbjct: 148 VRSALPAGCQATVLSLSSYYAATKVIDETQPLRALTKAVKRRVYLGSSRPDCPARETWRR 207 Query: 215 ELVYEQIPA 223 L + Sbjct: 208 VLAGSGVEV 216 >2WX2-A nrPDB Length = 473 Score = 29.8 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 32/78 (41%), Gaps = 5/78 (6%) Query: 91 PTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARH 150 P AV M R +AR E ++ + E ++ ++ KD + +G Sbjct: 196 PAAVFMPWLLRLPLPQSARCREARAELQKILGEIIVAREKEEASKDNNTSDLLGG----- 250 Query: 151 LLERVAPSGGKVTVLTHC 168 LL+ V G ++++ C Sbjct: 251 LLKAVYRDGTRMSLHEVC 268 >6IOZ-A nrPDB Length = 517 Score = 29.8 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 30/98 (30%), Gaps = 4/98 (4%) Query: 270 KHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIG--VWNPAFDV 327 K PF++A + ++ E + G+ +NP D+ Sbjct: 180 KTSASPFFLAVGYHKPHIPFRY--PKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDI 237 Query: 328 TPHDLITGGIITELGVFAPEELRTALTTTISSRDGTLD 365 + + I+ P + + + + + LD Sbjct: 238 RQREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLD 275 >6EOT-A nrPDB Length = 898 Score = 27.9 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 6/53 (11%), Positives = 15/53 (28%) Query: 282 SSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLIT 334 S + + + ++ A + P D TP ++ + Sbjct: 585 ISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFS 637 >4HDT-A nrPDB Length = 353 Score = 27.9 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 24/66 (36%), Gaps = 7/66 (10%) Query: 27 YEAVGSVHQAWEAIRAMKVRGAPAIALVGCL-------SLAVELQAGAGGPGLAALVAFV 79 + + + I A++ APA L +L+V L++ L +L + Sbjct: 230 IDECYTGDTVADIIAALRAHDAPAAGEAADLIATRSPIALSVTLESVRRAAKLQSLEDTL 289 Query: 80 RDKLSF 85 R + Sbjct: 290 RQEYRV 295 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.122 0.295 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,781,886 Number of Sequences: 36641 Number of extensions: 423003 Number of successful extensions: 1417 Number of sequences better than 10.0: 31 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1283 Number of HSP's gapped (non-prelim): 73 length of query: 369 length of database: 10,336,785 effective HSP length: 98 effective length of query: 271 effective length of database: 6,745,967 effective search space: 1828157057 effective search space used: 1828157057 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.5 bits)