BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BUT1 (245 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2AG5-A nrPDB 507 e-144 4M8S-A nrPDB 146 6e-36 4NBT-A nrPDB 142 1e-34 3WOH-A nrPDB 142 1e-34 2HQ1-A nrPDB 139 1e-33 5ITV-A nrPDB 137 3e-33 3RSH-A nrPDB 133 5e-32 2CFC-A nrPDB 133 8e-32 3FTP-A nrPDB 129 9e-31 1X1T-A nrPDB 129 9e-31 4Z9Y-A nrPDB 128 3e-30 1NFF-A nrPDB 126 7e-30 1Q7C-A nrPDB 126 9e-30 4JRO-A nrPDB 124 6e-29 4BO1-A nrPDB 122 1e-28 2FWM-X nrPDB 121 3e-28 3GRP-A nrPDB 120 4e-28 2Q2Q-A nrPDB 120 5e-28 4AVY-A nrPDB 120 7e-28 5YSS-A nrPDB 119 2e-27 4NBV-A nrPDB 117 4e-27 3OSU-A nrPDB 117 4e-27 2PNF-A nrPDB 117 4e-27 3UF0-A nrPDB 117 5e-27 1AE1-A nrPDB 117 5e-27 1K2W-A nrPDB 117 6e-27 4E6P-A nrPDB 117 6e-27 2UVD-A nrPDB 117 7e-27 2C07-A nrPDB 116 1e-26 3V2H-A nrPDB 115 2e-26 3W8F-A nrPDB 115 2e-26 3EMK-A nrPDB 113 7e-26 5CDY-A nrPDB 113 1e-25 4DMM-A nrPDB 113 1e-25 4HP8-A nrPDB 112 1e-25 5U9P-A nrPDB 110 8e-25 3F9I-A nrPDB 110 8e-25 4CQL-A nrPDB 109 1e-24 4KMS-A nrPDB 108 3e-24 3LYL-A nrPDB 107 6e-24 5OJG-A nrPDB 106 1e-23 1GEE-A nrPDB 105 1e-23 3WTC-A nrPDB 105 1e-23 1GEG-A nrPDB 105 2e-23 4RZH-A nrPDB 104 3e-23 2PH3-A nrPDB 104 4e-23 2ZAT-A nrPDB 102 1e-22 3O4R-A nrPDB 102 1e-22 2EW8-A nrPDB 102 2e-22 2BGM-A nrPDB 102 2e-22 4CR6-A nrPDB 101 3e-22 3WYE-A nrPDB 101 3e-22 4IS3-A nrPDB 101 4e-22 4RZI-B nrPDB 100 7e-22 5JS6-A nrPDB 99 1e-21 1HXH-A nrPDB 99 1e-21 3V2G-A nrPDB 99 2e-21 4K6F-A nrPDB 99 2e-21 2NM0-A nrPDB 98 3e-21 2CDH-G nrPDB 98 4e-21 6NRP-A nrPDB 97 5e-21 5B1Y-A nrPDB 97 8e-21 1O5I-A nrPDB 96 1e-20 1CYD-A nrPDB 96 1e-20 3UN1-A nrPDB 96 2e-20 6CI9-A nrPDB 96 2e-20 4CQM-B nrPDB 95 3e-20 5VT6-A nrPDB 95 3e-20 3T7C-A nrPDB 95 3e-20 5OVL-A nrPDB 94 4e-20 5OVJ-A nrPDB 94 4e-20 2AE2-A nrPDB 94 6e-20 3UVE-A nrPDB 94 7e-20 3D3W-A nrPDB 94 8e-20 4DBZ-A nrPDB 93 9e-20 3RWB-A nrPDB 93 1e-19 4EGF-A nrPDB 92 2e-19 4IIV-A nrPDB 92 2e-19 3VZS-A nrPDB 91 5e-19 3AUT-A nrPDB 91 6e-19 4TRR-A nrPDB 91 7e-19 2GDZ-A nrPDB 90 8e-19 3OEC-A nrPDB 90 9e-19 3A28-C nrPDB 89 1e-18 4MOW-A nrPDB 89 2e-18 2HSD-A nrPDB 88 4e-18 2B4Q-A nrPDB 88 4e-18 3OIC-A nrPDB 87 1e-17 1UZM-A nrPDB 86 1e-17 1AHH-A nrPDB 86 2e-17 5T5Q-A nrPDB 86 2e-17 3EZL-A nrPDB 84 4e-17 5EJ2-A nrPDB 84 7e-17 4IIN-A nrPDB 84 8e-17 3RKU-A nrPDB 82 2e-16 5JY1-A nrPDB 82 3e-16 3OML-A nrPDB 81 4e-16 4GKB-A nrPDB 80 6e-16 1DOH-A nrPDB 79 1e-15 1YXM-A nrPDB 79 1e-15 3GDF-A nrPDB 78 3e-15 3V8B-A nrPDB 77 6e-15 3R3S-A nrPDB 76 2e-14 5IZ4-A nrPDB 74 5e-14 4FC7-A nrPDB 72 2e-13 2NWQ-A nrPDB 72 2e-13 1H5Q-A nrPDB 71 5e-13 5O3Z-A nrPDB 70 1e-12 3ZV3-A nrPDB 68 4e-12 3U5T-A nrPDB 67 9e-12 1BDB-A nrPDB 65 3e-11 2P91-A nrPDB 64 5e-11 2X9N-A nrPDB 64 5e-11 3PXX-A nrPDB 63 1e-10 3U4C-A nrPDB 62 2e-10 4RGB-A nrPDB 60 6e-10 2O23-A nrPDB 60 9e-10 1W73-A nrPDB 60 1e-09 1P33-A nrPDB 59 2e-09 1E3W-A nrPDB 59 2e-09 1FJH-A nrPDB 59 3e-09 3E9N-A nrPDB 57 6e-09 3PPI-A nrPDB 56 1e-08 2YW9-A nrPDB 55 4e-08 3OIG-A nrPDB 54 5e-08 6CGE-A nrPDB 54 5e-08 1A27-A nrPDB 54 5e-08 5KOI-A nrPDB 54 6e-08 4M89-A nrPDB 54 7e-08 5TF4-A nrPDB 54 9e-08 4DA9-A nrPDB 52 2e-07 3UCF-A nrPDB 52 2e-07 5ILO-A nrPDB 52 3e-07 5TQV-A nrPDB 52 3e-07 5YCX-A nrPDB 51 4e-07 2QHX-A nrPDB 51 4e-07 2BFA-A nrPDB 51 5e-07 1SNY-A nrPDB 50 9e-07 2DKN-A nrPDB 49 2e-06 3DWF-A nrPDB 48 3e-06 3U9L-A nrPDB 48 4e-06 4JQC-A nrPDB 48 5e-06 5CFZ-A nrPDB 47 6e-06 4ALL-A nrPDB 47 7e-06 5I9N-A nrPDB 46 1e-05 4NR0-A nrPDB 46 2e-05 4DRY-A nrPDB 45 2e-05 1B15-A nrPDB 42 2e-04 3K2E-A nrPDB 42 3e-04 3KZV-A nrPDB 42 4e-04 2PD3-A nrPDB 41 4e-04 4HBG-A nrPDB 41 5e-04 4ZJU-A nrPDB 40 0.001 5PGZ-A nrPDB 40 0.001 3GRK-A nrPDB 39 0.002 1MG5-A nrPDB 34 0.054 5WQO-A nrPDB 32 0.26 4NK4-A nrPDB 31 0.46 4J3F-A nrPDB 31 0.48 5K1S-A nrPDB 30 0.71 1OAA-A nrPDB 30 1.1 3VPX-A nrPDB 30 1.2 3OJO-A nrPDB 30 1.2 4IZE-A nrPDB 30 1.3 2CVJ-A nrPDB 29 2.3 3O26-A nrPDB 28 2.7 6ACF-A nrPDB 28 3.8 1EDZ-A nrPDB 27 6.1 4XT6-A nrPDB 27 7.7 5JE5-A nrPDB 27 7.9 >2AG5-A nrPDB Length = 246 Score = 507 bits (1306), Expect = e-144, Method: Compositional matrix adjust. Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM Sbjct: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV Sbjct: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID Sbjct: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 Query: 241 GGWSL 245 GGWSL Sbjct: 241 GGWSL 245 >4M8S-A nrPDB Length = 248 Score = 146 bits (369), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 88/247 (35%), Positives = 141/247 (57%), Gaps = 16/247 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQTRVLDV 59 L GK+ ++T A++GIG A A A GAKVI T +ES + L ++ G + RVL+ Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGG-EGRVLNS 64 Query: 60 TKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + ++ ++E+ LD+L N AG ++ +E++WD M +N++S++ KA Sbjct: 65 AEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKA 124 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 L M+ Q++G IIN++SV V G + Y+ KA +IG +KS+A + +GI NCV Sbjct: 125 VLRGMMKQRAGRIINITSVV-GVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCV 183 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG +DT R PEE R F + GRF A++IA ++LASD++ Y+TG Sbjct: 184 APGFIDTD------MTRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQ 237 Query: 236 PVIIDGG 242 + ++GG Sbjct: 238 TLHVNGG 244 >4NBT-A nrPDB Length = 240 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 85/251 (33%), Positives = 138/251 (54%), Gaps = 17/251 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 M +L+GKV ++T A+G+GQA ALA+A EGAKVIA D+ + +P ++ L+VT Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYS----HPNVEGMYLNVT 56 Query: 61 KKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 +++F V ++D+L N AG E WD +++N++ ++ + + Sbjct: 57 DVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLV 116 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG--IRCNC 174 P+M G+IIN+SSV V G + + Y+ TKA VIGLT + A +F +G +R N Sbjct: 117 GPQMQTNGYGSIINISSVV-GVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNA 175 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + T L+ P++ + F R EEIA + ++LASD+++YVTG Sbjct: 176 IAPGYIMTDILKTV------PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTG 229 Query: 235 NPVIIDGGWSL 245 + ++GG L Sbjct: 230 QTINVNGGMRL 240 >3WOH-A nrPDB Length = 251 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 89/256 (34%), Positives = 144/256 (56%), Gaps = 23/256 (8%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKV----IATDINESKLQ-ELEKYPGI-QTR 55 G L GKV ++T ++G+G+A AL AR+GA V ++ D + + Q E+E+ G ++ Sbjct: 7 GALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSY 66 Query: 56 VLDVTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV+ +Q+ + V +D+L N AG + G +++D+D MN N++ +L Sbjct: 67 RCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFL 126 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 IKA + ++SG+IIN+SSV S V G + Y++ KA +IGLTKS+A + ++ +R Sbjct: 127 FIKACYFGFIRKRSGSIINISSV-SGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVR 185 Query: 172 CNCVCPGTVDTPSLQERI--QARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 CN V PG + T Q+ + R +P R RF +E+A L +LA DES Sbjct: 186 CNAVAPGLIATDMTQDLVDDSKRLDPVPMR----------RFGRPDEVAGLVAFLAGDES 235 Query: 230 AYVTGNPVIIDGGWSL 245 +Y+TG V +DGG ++ Sbjct: 236 SYITGQVVCVDGGMAM 251 >2HQ1-A nrPDB Length = 247 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 88/251 (35%), Positives = 136/251 (54%), Gaps = 19/251 (7%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKYPGIQTRVL 57 +L GK I+T +++G+G+A A GA ++ A+ ++ +E K GI V Sbjct: 2 QLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEF-KAAGINVVVA 60 Query: 58 --DVTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV + ++ + R+D+L N AG +L EKDWD +N N++S YL Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYL 120 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 KA ML QKSG IIN++S+A + G + Y+ +KA +IG TKS+A +F +GI Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGII-GNAGQANYAASKAGLIGFTKSIAKEFAAKGIY 179 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 CN V PG + T + + + P++ + +L RF T EE+A + +LASD+S Y Sbjct: 180 CNAVAPGIIKT-DMTDVL-----PDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 232 VTGNPVIIDGG 242 +TG + IDGG Sbjct: 234 ITGQVINIDGG 244 >5ITV-A nrPDB Length = 255 Score = 137 bits (346), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 88/252 (34%), Positives = 133/252 (52%), Gaps = 12/252 (4%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL------EKYPGIQTRV 56 L K +++T A GIG AA AF + A V+ DI+E++ + + ++ +QT + Sbjct: 4 NLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDI 63 Query: 57 LDVTK-KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 D + ++ + LDVL N AG + + E DW+ + +N+ M+LM K Sbjct: 64 TDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKH 123 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 L MLA GNIIN SV V + Y+ +K V+ LTKS+A D+ + IR NCV Sbjct: 124 ALKHMLAAGKGNIINTCSVGGLV-AWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCV 182 Query: 176 CPGTVDTPSLQERI---QARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 CPG +DTP L E+ G EE + + K R EEIA + ++LASD S+Y+ Sbjct: 183 CPGIIDTP-LNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYM 241 Query: 233 TGNPVIIDGGWS 244 TG+ + DGG++ Sbjct: 242 TGSAITADGGYT 253 >3RSH-A nrPDB Length = 251 Score = 133 bits (335), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 83/248 (33%), Positives = 131/248 (52%), Gaps = 13/248 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDVTK 61 L+GKV ++T A++GIG+A A A GAKVI T +ES Q + Y G + L+VT Sbjct: 10 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTN 69 Query: 62 KKQID----QFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + I+ +E +D+L N AG ++ +E++W M N+ S++ + KA L Sbjct: 70 PESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKAVL 129 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G IIN+ SV ++ G + Y+ KA VIG TKS+A + +G+ N V P Sbjct: 130 RGMMKKRQGRIINVGSVVGTM-GNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAP 188 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G ++T + +E R L + GR EIA +LAS E+AY+TG + Sbjct: 189 GFIETD------MTKALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGETL 242 Query: 238 IIDGGWSL 245 ++GG + Sbjct: 243 HVNGGMYM 250 >2CFC-A nrPDB Length = 250 Score = 133 bits (334), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 88/251 (35%), Positives = 137/251 (54%), Gaps = 18/251 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK--YPGIQTRVL----DVT 60 +V I+T A+ G G A A F G +V A D++ L+E + + +VL DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 61 KKKQIDQ-FANEVER---LDVLFNVAGFVHH---GTVLDCEEKDWDFSMNLNVRSMYLMI 113 + ++ A +E+ +DVL N AG + G + + +D M +NVR ++L Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 +A LP ML Q +G I+N++SVAS V R Y+T+K AV+ LTKSVA D+ GIRCN Sbjct: 123 RAVLPHMLLQGAGVIVNIASVASLVA-FPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCN 181 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 VCPG ++TP Q R+ + E R+ L R TA ++A ++LA +++ YV Sbjct: 182 AVCPGMIETPMTQWRL----DQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVN 237 Query: 234 GNPVIIDGGWS 244 G +++DG ++ Sbjct: 238 GAALVMDGAYT 248 >3FTP-A nrPDB Length = 270 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 132/248 (53%), Gaps = 16/248 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---KYPGIQTR--VLD 58 LD +V I+T A++GIG+A AL AR GA VI T E+ + + K G++ R VL+ Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLN 85 Query: 59 VTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V +D E L+VL N AG + ++ +WD ++ N+++++ + + Sbjct: 86 VNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRLSR 145 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 A L M+ + G I+N++SV S G + Y+ KA V G+T+++A + +GI NC Sbjct: 146 AVLRPMMKARGGRIVNITSVVGSA-GNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNC 204 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG +DT +G P+E + + GR + E+IA +LAS ++ Y+TG Sbjct: 205 VAPGFIDTD------MTKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITG 258 Query: 235 NPVIIDGG 242 + ++GG Sbjct: 259 TTLHVNGG 266 >1X1T-A nrPDB Length = 260 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 86/260 (33%), Positives = 135/260 (51%), Gaps = 22/260 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY-PGIQT----RVL- 57 L GKV ++T + GIG A A A +GA ++ ++ E+EK G+ +VL Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAA--EIEKVRAGLAAQHGVKVLY 59 Query: 58 ---DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 D++K + +D ++ R+D+L N AG H + D + WD + LN+ +++ Sbjct: 60 DGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVF 119 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 A LP M Q G IIN++S A + N+ Y K V+G TK A + QGI Sbjct: 120 HGTAAALPHMKKQGFGRIINIAS-AHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGI 178 Query: 171 RCNCVCPGTVDTPSLQERIQA----RGNPEE--ARNDFLKRQKTGRFATAEEIAMLCVYL 224 N +CPG V TP ++++I A G +E AR ++Q + +F T E++ V+L Sbjct: 179 TANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFL 238 Query: 225 ASDESAYVTGNPVIIDGGWS 244 ASD +A +TG V +DGGW+ Sbjct: 239 ASDAAAQITGTTVSVDGGWT 258 >4Z9Y-A nrPDB Length = 253 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 76/249 (30%), Positives = 134/249 (53%), Gaps = 15/249 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT--- 60 L GKV ++T G+GQ A+ A+ G ++ +I E K +EK + R L +T Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPK-DTIEKVTALGRRFLSLTADM 66 Query: 61 -----KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + +++ E +D+L N AG + ++ EK+WD MNLN++S++ M + Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQT 126 Query: 116 FLPKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + + Q K G IIN++S+ S +G + Y+ +K+AV+G+T+ +A ++ + GI N Sbjct: 127 VARQFIKQGKGGKIINIASML-SFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNA 185 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + T + Q Q R + E ++ + L R GR+ +++ V+LAS S Y+ G Sbjct: 186 IAPGYMATNNTQ---QLRADEERSK-EILDRIPAGRWGLPQDLMGPSVFLASSASDYING 241 Query: 235 NPVIIDGGW 243 + +DGGW Sbjct: 242 YTIAVDGGW 250 >1NFF-A nrPDB Length = 260 Score = 126 bits (317), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 90/247 (36%), Positives = 130/247 (52%), Gaps = 18/247 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI--NESKLQELEKYPGIQTRVLDV 59 GRL GKV +++ A+G+G + A EGAKV+ DI E K E + LDV Sbjct: 3 GRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDV 62 Query: 60 TKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T+ Q +D L VL N AG ++ GT+ D +W +++N+ ++L I+A Sbjct: 63 TQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRA 122 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + M G+IIN+SS+ + G V Y+ TK AV GLTKS A + GIR N + Sbjct: 123 VVKPMKEAGRGSIINISSI-EGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSI 181 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG V TP + + + PE+ + + GR A E++ L VYLASDES+Y TG Sbjct: 182 HPGLVKTP-MTDWV-----PED-----IFQTALGRAAEPVEVSNLVVYLASDESSYSTGA 230 Query: 236 PVIIDGG 242 ++DGG Sbjct: 231 EFVVDGG 237 >1Q7C-A nrPDB Length = 244 Score = 126 bits (316), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 133/248 (53%), Gaps = 13/248 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDVTK 61 +GK+ ++T A++GIG+A A A GAKVI T +E+ Q + Y G + +L+VT Sbjct: 3 FEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTD 62 Query: 62 KKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 I+ ++ +D+L N AG ++ ++++W+ + N+ S++ + KA + Sbjct: 63 PASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVM 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G II + SV ++ G + ++ KA +IG +KS+A + +GI N V P Sbjct: 123 RAMMKKRHGRIITIGSVVGTM-GNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVAP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G ++T R ++ R L + GR A+EIA +LASDE+AY+TG + Sbjct: 182 GFIETD------MTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETL 235 Query: 238 IIDGGWSL 245 ++GG + Sbjct: 236 HVNGGMYM 243 >4JRO-A nrPDB Length = 271 Score = 124 bits (310), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 134/253 (52%), Gaps = 19/253 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES-----KLQELEKYPGIQTRVL- 57 L GKV ++T ++GIG+ A+ A+EGA + + N S + +L G++ + Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIF-FNYNGSPEAAEETAKLVAEHGVEVEAMK 85 Query: 58 -DVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +V + +D F + R+D+L N AG ++ +E +WD +N+N++ +L Sbjct: 86 ANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFLC 145 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 KA M+ Q++G IINM+SV + G + Y +KA VIGLTK+ A + +GI Sbjct: 146 TKAVSRTMMKQRAGKIINMASVVGLI-GNAGQANYVASKAGVIGLTKTTARELAPRGINV 204 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N V PG + T + +++ E+ + L + G + T E+IA ++LASD S Y+ Sbjct: 205 NAVAPGFI-TTDMTDKLD-----EKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYI 258 Query: 233 TGNPVIIDGGWSL 245 TG + +DGG + Sbjct: 259 TGQTLSVDGGMVM 271 >4BO1-A nrPDB Length = 269 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 84/248 (33%), Positives = 129/248 (52%), Gaps = 16/248 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES---KLQELEKYPGIQTR--VLD 58 L GKV ++T A++GIGQA AL R GA VI T + S K+ E K G++ VLD Sbjct: 25 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLD 84 Query: 59 VTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V+ + + + + + ++ N AG ++ ++ +W +N N+ S+Y + K Sbjct: 85 VSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSK 144 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 A L M + G IIN+ SV ++ G + Y+ KA + G T+++A + + I N Sbjct: 145 AVLRGMTKARWGRIINIGSVVGAM-GNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNA 203 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG +DT +E PE R L + GR AEEIA + +LASD +AYVTG Sbjct: 204 VAPGFIDTDMTREL------PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTG 257 Query: 235 NPVIIDGG 242 V ++GG Sbjct: 258 ATVPVNGG 265 >2FWM-X nrPDB Length = 250 Score = 121 bits (303), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 129/255 (50%), Gaps = 18/255 (7%) Query: 2 GRLD--GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDV 59 G +D GK + +T A +GIG A ALAF GAKV T +++ QE +YP T V+DV Sbjct: 1 GHMDFSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQE--QYP-FATEVMDV 55 Query: 60 TKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 Q+ Q E ERLD L N AG + G ++DW + +NV + + + Sbjct: 56 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 115 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + + Q+ G I+ ++S A+ + Y +KAA+ L SV + G+RCN V Sbjct: 116 TMNQFRRQRGGAIVTVASDAAHTP-RIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 174 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQ-----KTGRFATAEEIAMLCVYLASDESA 230 PG+ DT +Q + + EE R Q G+ A +EIA ++LASD ++ Sbjct: 175 SPGSTDT-DMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 233 Query: 231 YVTGNPVIIDGGWSL 245 ++T +++DGG +L Sbjct: 234 HITLQDIVVDGGSTL 248 >3GRP-A nrPDB Length = 266 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 132/251 (52%), Gaps = 13/251 (5%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--D 58 M +L G+ ++T A GIG+A A F +GA V E KL+E+ G V + Sbjct: 22 MFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSAN 81 Query: 59 VTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ +K I Q A E+E +D+L N AG G + +++DWD + +N+ + + + Sbjct: 82 LSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTR 141 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + M+ ++ G IIN++S+ V G + Y KA +IG +K++A + + I NC Sbjct: 142 ELIHSMMRRRYGRIINITSIVGVV-GNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNC 200 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + + ++ +++ E+ + + R EEIA VYLASDE+AY+TG Sbjct: 201 IAPGFIKS-AMTDKLN-----EKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTG 254 Query: 235 NPVIIDGGWSL 245 + I+GG ++ Sbjct: 255 QTLHINGGMAM 265 >2Q2Q-A nrPDB Length = 255 Score = 120 bits (301), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 127/253 (50%), Gaps = 15/253 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK--LQELEKYPGIQT--RVLDV 59 L GK ++T + GIG A AR GA ++ + L E+ ++ G++ D+ Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARH-GVKAVHHPADL 60 Query: 60 TKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + QI+ ER +D+L N AG H V + WD + LN+ +++ + Sbjct: 61 SDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRL 120 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 LP M A+ G IIN++SV V G + Y K V+GLTK V + + CN + Sbjct: 121 ALPGMRARNWGRIINIASVHGLV-GSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAI 179 Query: 176 CPGTVDTPSLQERIQAR----GNPEEARNDFL-KRQKTGRFATAEEIAMLCVYLASDESA 230 CPG V TP +Q++I R G+P +A++D L ++Q + F T E + L ++L S+ + Sbjct: 180 CPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGS 239 Query: 231 YVTGNPVIIDGGW 243 V G +DGGW Sbjct: 240 QVRGAAWNVDGGW 252 >4AVY-A nrPDB Length = 242 Score = 120 bits (300), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 134/241 (55%), Gaps = 15/241 (6%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 G+ +++T + GIG A A+ FA GA+V+A ++ + ++P I+ LD+T +++ Sbjct: 11 GQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHA-PRHPRIRREELDITDSQRL 69 Query: 66 DQFANEVERLDVLFNVAGFVHHGTVLDCEEKD---WDFSMNLNVRSMYLMIKAFLPKMLA 122 + + RLDVL N AG D EE D ++ + LN+ + L + P +LA Sbjct: 70 QRLFEALPRLDVLVNNAGISR-----DREEYDLATFERVLRLNLSAAMLASQLARP-LLA 123 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 Q+ G+I+N++S+ S+ G +R YS +K A++ LT+S+A ++ + IR N + PG +DT Sbjct: 124 QRGGSILNIASMYSTF-GSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDT 182 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 P L ++A EA ++R R+ A E+A +L +++VTG + +DGG Sbjct: 183 P-LGAGLKA---DVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGG 238 Query: 243 W 243 + Sbjct: 239 Y 239 >5YSS-A nrPDB Length = 256 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 82/254 (32%), Positives = 127/254 (50%), Gaps = 17/254 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIAT---DINESK--LQELEKYPGIQTRVLD 58 L GK ++T + GIG A A+ GA +I D++ +K + + K PG D Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGA--D 60 Query: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ + QI E +D+L N AG H + W+ + +N+ S++ + Sbjct: 61 LSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTR 120 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 LP M A+ G IIN++SV V + Y K V+GLTK++A + Q I CN Sbjct: 121 LALPGMRARNWGRIINIASVHGLVASK-EKSAYVAAKHGVVGLTKTIALETAQTEITCNA 179 Query: 175 VCPGTVDTPSLQERIQAR----GNPEEARNDFL-KRQKTGRFATAEEIAMLCVYLASDES 229 +CPG V TP +Q++I R PE AR+ L ++Q + F T E++ L ++L SD + Sbjct: 180 LCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGA 239 Query: 230 AYVTGNPVIIDGGW 243 A V G +DGGW Sbjct: 240 AQVRGVAWNMDGGW 253 >4NBV-A nrPDB Length = 246 Score = 117 bits (293), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 80/252 (31%), Positives = 128/252 (50%), Gaps = 16/252 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG-----IQTRVL 57 +L G+V I+T AA GIG A A FA +GA V+ D+ E++++E + + Sbjct: 2 KLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRV 61 Query: 58 DVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DVT++ ++D V +R+D+L N AG + E +D +++N++ ++ Sbjct: 62 DVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNCA 121 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 +A M Q G I+N SSV + G + Y+ +K VIG TK+ A + +G+R N Sbjct: 122 QAVAGLMTEQGKGVILNASSVV-GLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVN 180 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 VCPG V+T LQ P++ + R A EIA + +LASD+++YV Sbjct: 181 AVCPGFVNTEILQTV------PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVN 234 Query: 234 GNPVIIDGGWSL 245 G + GG SL Sbjct: 235 GVAIEASGGMSL 246 >3OSU-A nrPDB Length = 246 Score = 117 bits (293), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 129/250 (51%), Gaps = 19/250 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATD----------INESKLQELEKYPGIQTRV 56 K ++T A++GIG++ AL A EG V + E K + ++ + IQ V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFA-IQANV 63 Query: 57 LDVTK-KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 D + K I + ++ LDVL N AG ++ +E++WD ++ N++ ++ I+ Sbjct: 64 ADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQK 123 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 P+ML Q+SG IIN+SSV +V G + Y TKA VIGLTKS A + +GI N V Sbjct: 124 ATPQMLRQRSGAIINLSSVVGAV-GNPGQANYVATKAGVIGLTKSAARELASRGITVNAV 182 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG + + + + +E + L + RF +IA +LASD++ Y+TG Sbjct: 183 APGFI-VSDMTDAL-----SDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQ 236 Query: 236 PVIIDGGWSL 245 + ++GG + Sbjct: 237 TIHVNGGMYM 246 >2PNF-A nrPDB Length = 248 Score = 117 bits (293), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 131/250 (52%), Gaps = 17/250 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---------KYPGIQ 53 +L GKV ++T + +GIG+A A A G+ VI T + + + + K G++ Sbjct: 4 KLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVE 63 Query: 54 TRVL-DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +L + + K ++ N V+ +D+L N AG L DW+ + +N+ +L+ Sbjct: 64 MNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLV 123 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + L KM+ Q+ G I+N+SSV G V + YSTTKA +IG TKS+A + + + Sbjct: 124 TQNSLRKMIKQRWGRIVNISSVV-GFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N V PG ++T EE + + ++ GRF + EE+A + ++L S+ ++Y+ Sbjct: 183 NAVAPGFIETDMTAVL------SEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYI 236 Query: 233 TGNPVIIDGG 242 TG + ++GG Sbjct: 237 TGEVIHVNGG 246 >3UF0-A nrPDB Length = 273 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 132/250 (52%), Gaps = 18/250 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIA---TDINESKLQELEKYPG-IQTRVLDV 59 L G+ ++T A GIG+A A +AR GA V+A TD + E+ G + V D+ Sbjct: 29 LAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVADL 88 Query: 60 TKKKQIDQFANEV---ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + A E+ R+DVL N AG + + W + +N+ + +++ ++F Sbjct: 89 ADLEGAANVAEELAATRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLSRSF 148 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 MLA SG I+ ++S+ S +G N Y+ +K AV+GLT+++A+++ +G+ N + Sbjct: 149 GTAMLAHGSGRIVTIASMLS-FQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNALA 207 Query: 177 PG---TVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 PG T +T +L R + E A + R GR+AT E++ V+LASD ++YV Sbjct: 208 PGYVVTANTAAL------RADDERA-AEITARIPAGRWATPEDMVGPAVFLASDAASYVH 260 Query: 234 GNPVIIDGGW 243 G + +DGGW Sbjct: 261 GQVLAVDGGW 270 >1AE1-A nrPDB Length = 273 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 129/251 (51%), Gaps = 11/251 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGIQTRVLD 58 L G ++T ++GIG A A GA+V NE +L E EK ++ V D Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCD 78 Query: 59 VTKKKQIDQFANEVE-----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + + + D+ V +L++L N AG V H D EKD++ M N + Y + Sbjct: 79 LLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLS 138 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 + P + A ++GN+I +SS+A + + +YS +K A+ +TKS+A ++ + IR N Sbjct: 139 QIAYPLLKASQNGNVIFLSSIAG-FSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVN 197 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + TP ++ I+ + +E ++F+ + GR +E++ L +L ++Y+T Sbjct: 198 SVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYIT 257 Query: 234 GNPVIIDGGWS 244 G + DGG++ Sbjct: 258 GQIIWADGGFT 268 >1K2W-A nrPDB Length = 256 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 84/254 (33%), Positives = 124/254 (48%), Gaps = 14/254 (5%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN--ESKLQELEKYPGIQTRVLDVT 60 RLDGK ++T +A+GIG+A A A+ REGA+V DIN ++ E P LDVT Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVT 61 Query: 61 KKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + ID+ E+ +D+L N A +++ + +D +NV M++A Sbjct: 62 DQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQAV 121 Query: 117 LPKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 M+A + G IINM+S A +G VY TKAAVI LT+S + I+ GI N + Sbjct: 122 ARAMIAGGRGGKIINMASQAGR-RGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAI 180 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQ-----KTGRFATAEEIAMLCVYLASDESA 230 PG VD + E KRQ GR AE++ + ++LA+ E+ Sbjct: 181 APGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEAD 240 Query: 231 YVTGNPVIIDGG-W 243 Y+ +DGG W Sbjct: 241 YIVAQTYNVDGGNW 254 >4E6P-A nrPDB Length = 259 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 87/257 (33%), Positives = 131/257 (50%), Gaps = 16/257 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL--EKYPGIQTRVLD 58 M RL+GK ++T +A+GIG+A A A+ REGA V DI+ + ++ E P +D Sbjct: 3 MKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMD 62 Query: 59 VTKKKQIDQ-FANEVER---LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 VT++ ID A VE LD+L N A +++ + ++ +NV ++ Sbjct: 63 VTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQ 122 Query: 115 AFLPKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 A +M+AQ + G IINM+S A +G +Y TKAAVI LT+S D I+ I N Sbjct: 123 AAARQMIAQGRGGKIINMASQAGR-RGEALVAIYCATKAAVISLTQSAGLDLIKHRINVN 181 Query: 174 CVCPGTVD------TPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 + PG VD +L R + R E+ R + GR TAE++ + ++LAS Sbjct: 182 AIAPGVVDGEHWDGVDALFARYENRPRGEKKRL-VGEAVPFGRMGTAEDLTGMAIFLASA 240 Query: 228 ESAYVTGNPVIIDGG-W 243 ES Y+ +DGG W Sbjct: 241 ESDYIVSQTYNVDGGNW 257 >2UVD-A nrPDB Length = 246 Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 85/259 (32%), Positives = 134/259 (51%), Gaps = 31/259 (11%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-NESK----LQELEKY--PGIQTRV 56 L GKV ++T A++GIG+A A+ A++GA V+ NE K + E++K I R Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 57 -----LDVTK--KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSM 109 DVT K+ +D F ++D+L N AG ++ +E++WD +N N++ + Sbjct: 62 DVANAEDVTNMVKQTVDVFG----QVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGV 117 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 +L KA M+ Q+ G I+N++SV V G + Y KA VIGLTK+ A + + Sbjct: 118 FLCTKAVSRFMMRQRHGRIVNIASVV-GVTGNPGQANYVAAKAGVIGLTKTSAKELASRN 176 Query: 170 IRCNCVCPGTVDTPS---LQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 I N + PG + T L E I+A + LK +F A++IA + AS Sbjct: 177 ITVNAIAPGFIATDMTDVLDENIKA---------EMLKLIPAAQFGEAQDIANAVTFFAS 227 Query: 227 DESAYVTGNPVIIDGGWSL 245 D+S Y+TG + +DGG + Sbjct: 228 DQSKYITGQTLNVDGGMVM 246 >2C07-A nrPDB Length = 285 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 133/250 (53%), Gaps = 18/250 (7%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE----SKLQELEKYPGIQTRVL--D 58 + KV ++T A +GIG+ A A+ + VI + S + E++ + G ++ D Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSF-GYESSGYAGD 101 Query: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V+KK++I + N++ + +D+L N AG L + +W+ + N+ S++ + + Sbjct: 102 VSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQ 161 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 +M+ + G IIN+SS+ + G V + YS++KA VIG TKS+A + + I N Sbjct: 162 PISKRMINNRYGRIINISSIVG-LTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNA 220 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + + + ++I E+ + + + GR T EE+A L +L+SD+S Y+ G Sbjct: 221 IAPGFI-SSDMTDKIS-----EQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYING 274 Query: 235 NPVIIDGGWS 244 +IDGG S Sbjct: 275 RVFVIDGGLS 284 >3V2H-A nrPDB Length = 281 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 84/259 (32%), Positives = 129/259 (49%), Gaps = 26/259 (10%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKYPG--IQTRVLDV 59 K ++T + GIG A A A+ GA ++ A D + E+ + D+ Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 85 Query: 60 TKKKQI-DQFANEVERL---DVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 TK +I D A +R D+L N AG + D + WD + +N+ S + I+ Sbjct: 86 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 145 Query: 116 FLPKMLAQKSGNIINMSS----VASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 +P M + G IIN++S VAS K Y K ++GLTK+VA + + G+ Sbjct: 146 AIPPMKKKGWGRIINIASAHGLVASPFK-----SAYVAAKHGIMGLTKTVALEVAESGVT 200 Query: 172 CNCVCPGTVDTPSLQERI----QARGNPEEA--RNDFLKRQKTGRFATAEEIAMLCVYLA 225 N +CPG V TP ++++I + RG EE LK Q T +F T E++A L +YLA Sbjct: 201 VNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLA 260 Query: 226 SDESAYVTGNPVIIDGGWS 244 D++A +TG V +DGGW+ Sbjct: 261 GDDAAQITGTHVSMDGGWT 279 >3W8F-A nrPDB Length = 260 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 127/258 (49%), Gaps = 18/258 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTRVL- 57 L GK ++T + GIG A A A+ GA V+ E + LE G++ L Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 58 -DVTKKKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 D++ + F A + LD+L N AG H + + W+ + LN+ +++ Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 A LP M Q G IIN++S A + VN+ Y K V+GLTK A + +GI C Sbjct: 122 TAAALPIMQKQGWGRIINIAS-AHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITC 180 Query: 173 NCVCPGTVDTPSLQERIQARGNPE------EARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 N +CPG V TP ++++I+A + AR ++Q + +F T E++ V+L+S Sbjct: 181 NAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS 240 Query: 227 DESAYVTGNPVIIDGGWS 244 + +TG + +DGGW+ Sbjct: 241 AAADQMTGTTLSLDGGWT 258 >3EMK-A nrPDB Length = 246 Score = 113 bits (283), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 130/248 (52%), Gaps = 13/248 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVTK 61 L G+ ++T A G+G+A A A +GA V E KL+EL G + V +++ Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSD 64 Query: 62 KKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 ++ + + E +D+L N AG G + ++DWD + +N+ S++ + + Sbjct: 65 REAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTRELT 124 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ +++G IIN++S+ V G + Y +KA +IG +KS+A + + + NC+ P Sbjct: 125 HPMMRRRNGRIINITSIV-GVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAP 183 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G +++ ++ ++ E+ ++ + R +IA VYLASDE+AYVTG + Sbjct: 184 GFIES-AMTGKLN-----EKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTL 237 Query: 238 IIDGGWSL 245 ++GG ++ Sbjct: 238 HVNGGMAM 245 >5CDY-A nrPDB Length = 244 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 126/248 (50%), Gaps = 13/248 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDVTK 61 +GK+ ++T A++GIG+A A GA VI T +E + + Y G + +L+V Sbjct: 3 FEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVD 62 Query: 62 KKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 ID E +D+L N AG ++ ++ +W ++ N+ S++ + KA + Sbjct: 63 PTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVM 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G II + SV ++ G + Y+ KA VIG +KS+A + +GI N V P Sbjct: 123 RAMMKKRFGRIITIGSVVGTM-GNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVAP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G ++T R ++ R L + R A+EIA +LASDE++Y++G + Sbjct: 182 GFIETD------MTRTLTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGETL 235 Query: 238 IIDGGWSL 245 ++GG + Sbjct: 236 HVNGGMYM 243 >4DMM-A nrPDB Length = 269 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 83/250 (33%), Positives = 121/250 (48%), Gaps = 21/250 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L ++ ++T A++GIG+A AL A GAKV + + + K Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKA 85 Query: 64 QIDQ-------FANEVER---LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + Q FA +ER LDVL N AG +L + DW ++LN+ ++L Sbjct: 86 DVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCS 145 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 +A ML Q+SG IIN++SV + G + YS KA VIGLTK+VA + +GI N Sbjct: 146 RAAAKIMLKQRSGRIINIASVVGEM-GNPGQANYSAAKAGVIGLTKTVAKELASRGITVN 204 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE-SAYV 232 V PG + T E A L+ GR+ A E+A + +LA+D +AY+ Sbjct: 205 AVAPGFIATDM---------TSELAAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYI 255 Query: 233 TGNPVIIDGG 242 TG + IDGG Sbjct: 256 TGQVINIDGG 265 >4HP8-A nrPDB Length = 247 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 136/248 (54%), Gaps = 18/248 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVI--ATDINESKLQELEKYPGIQTRVL---- 57 L+G+ ++T A G+GQA A+ A GA+V+ A + L + K G + +L Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFA 66 Query: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 D K D F + D+L N AG + ++ E DWD M++N+++++ +AF Sbjct: 67 DPLAAK--DSFTDA--GFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFA 122 Query: 118 PKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 ++LA+ +SG ++N++S+ S +G + Y+ K V GLTK +A ++ +GI N + Sbjct: 123 KELLAKGRSGKVVNIASLL-SFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIA 181 Query: 177 PGTVDTPSLQERIQARGNPEEARND-FLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG ++T + E ++A + ARN L+R GR+ +E+IA V+L+S + YV G Sbjct: 182 PGYIETNN-TEALRA----DAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGA 236 Query: 236 PVIIDGGW 243 + +DGGW Sbjct: 237 ILNVDGGW 244 >5U9P-A nrPDB Length = 265 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 79/251 (31%), Positives = 122/251 (48%), Gaps = 18/251 (7%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL------EKYPGIQTRV 56 RLDG+ ++T + +GIG A A GA ++ D NE K L E + V Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHA-V 75 Query: 57 LDVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 DV + Q ID+F V +D+L N AG + E DW M +N+ ++ + Sbjct: 76 FDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNV 135 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 +A M+A+ G IIN+ SV S + Y+ TK AV LTK + AD+ + GI+ Sbjct: 136 AQAVARHMIARGHGKIINICSVQSEL-ARPTIAPYAATKGAVRMLTKGMCADWARYGIQA 194 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFL-KRQKTGRFATAEEIAMLCVYLASDESAY 231 N + PG +T + + + A +D+L KR GR+ +E+ ++LAS S + Sbjct: 195 NGLAPGYFETELNRALVD-----DAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDF 249 Query: 232 VTGNPVIIDGG 242 V G + +DGG Sbjct: 250 VNGQTLFVDGG 260 >3F9I-A nrPDB Length = 249 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 132/245 (53%), Gaps = 15/245 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGIQTRVLD 58 L GK ++T A+ GIG A A + G+KVI + NE KL+ L + Y V + Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYT---IEVCN 68 Query: 59 VTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 + K++ ++ LD+L AG + +++D+D +++N+++ +++ + + Sbjct: 69 LANKEECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIK 128 Query: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPG 178 KM+ ++ G IIN+SS+ + G + Y +KA +IG+TKS++ + +GI N V PG Sbjct: 129 KMIQKRYGRIINISSIV-GIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPG 187 Query: 179 TVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVI 238 + + + +++ E+ R +++ G + E++A +LAS+ ++Y+TG + Sbjct: 188 FIKS-DMTDKLN-----EKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTLH 241 Query: 239 IDGGW 243 ++GG Sbjct: 242 VNGGM 246 >4CQL-A nrPDB Length = 261 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 129/258 (50%), Gaps = 25/258 (9%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE---LEKYPGIQTRV--- 56 RL + ++T A GIG+A ++ A EGA V A D++ + QE L PG + Sbjct: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 Query: 57 ------LDVTKKKQIDQFANEVERL-----DVLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105 DV++ + +V+ V+ + AG +L E DWD + +N Sbjct: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 Query: 106 VRSMYLMIKAFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 ++ +L+ +A +++ G+IIN+SS+ V G V + Y+ +KA VIGLT++ A + Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-GNVGQTNYAASKAGVIGLTQTAARE 186 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 + GIRCN V PG + TP Q+ P++ + + G E++A + +L Sbjct: 187 LGRHGIRCNSVLPGFIATPMTQKV------PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 Query: 225 ASDESAYVTGNPVIIDGG 242 AS++S Y+TG V + GG Sbjct: 241 ASEDSGYITGTSVEVTGG 258 >4KMS-A nrPDB Length = 249 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 122/245 (49%), Gaps = 13/245 (5%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDI-NESKLQELEKYPGIQTRVLDVTKKKQI 65 ++ I+T +GIG+A AL +G V+A N +E+E+ GI+T+ +V ++ Sbjct: 11 EIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCWNVADFEEC 70 Query: 66 DQFANEVER-----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 Q E+E + +L N AG + +DW+ +N+N+ S + M + + +M Sbjct: 71 RQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQM 130 Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 Q G I+N+SS+ + G V + YS KA +IG TK++A + + I NC+ PG + Sbjct: 131 RNQDYGRIVNISSINAQA-GQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYI 189 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 T E + A PE+ + R EEIA +L + + ++TG + I+ Sbjct: 190 AT----EMVGAV--PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISIN 243 Query: 241 GGWSL 245 GG ++ Sbjct: 244 GGHNM 248 >3LYL-A nrPDB Length = 247 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 131/248 (52%), Gaps = 16/248 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---KYPGIQTR--VLD 58 L+ KV ++T A++GIG A A A +GA V+ T +++ ++ E K G + R VL+ Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLN 62 Query: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ + I F E++ +D+L N AG ++ E +W +N N+ S++ M K Sbjct: 63 ISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSK 122 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + M+ ++ G II++ SV S G + Y KA VIG +KS+A + + I N Sbjct: 123 ECVRGMMKKRWGRIISIGSVVGSA-GNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNV 181 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG + T + +++ +E ++ + +G+ ++IA +LAS+E+ Y+TG Sbjct: 182 VAPGFIAT-DMTDKL-----TDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITG 235 Query: 235 NPVIIDGG 242 + ++GG Sbjct: 236 QTLHVNGG 243 >5OJG-A nrPDB Length = 260 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 121/251 (48%), Gaps = 13/251 (5%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE---------LEKYPGIQ 53 R +GKV I+TAA +GIG A A EGA V+ N+ + E L K GI Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 54 TRVLDVTKKKQIDQFA-NEVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMYL 111 + +K++ F + ++++L N G G +L+ ++ WD +NV++ + Sbjct: 67 GHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQ 126 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 M K P +A++ G I ++ S+ K Y TK ++GLT+++A + IR Sbjct: 127 MTKLVHPH-IAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIR 185 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 N + PG + T Q + E+ D ++ GR ++ A YLASD+S+Y Sbjct: 186 VNGIAPGVIKTKMSQVLWDGGEDAEKELTD-IQEIALGRLGVPDDCAGTVAYLASDDSSY 244 Query: 232 VTGNPVIIDGG 242 +TG +II GG Sbjct: 245 ITGEMIIIAGG 255 >1GEE-A nrPDB Length = 261 Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 132/256 (51%), Gaps = 22/256 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIAT-----DINESKLQELEKYPGIQTRVL- 57 L+GKV+++T ++ G+G++ A+ FA E AKV+ D S L+E++K G V Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 58 DVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL-- 111 DVT + + E +LDV+ N AG + + + DW+ ++ N+ +L Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 112 --MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 IK F+ + G +INMSSV + + Y+ +K + +T+++A ++ +G Sbjct: 125 REAIKYFVENDI---KGTVINMSSVHEKIPWPL-FVHYAASKGGMKLMTETLALEYAPKG 180 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 IR N + PG ++TP E+ +PE+ R D G EEIA + +LAS E+ Sbjct: 181 IRVNNIGPGAINTPINAEKF---ADPEQ-RADVESMIPMGYIGEPEEIAAVAAWLASSEA 236 Query: 230 AYVTGNPVIIDGGWSL 245 +YVTG + DGG +L Sbjct: 237 SYVTGITLFADGGMTL 252 >3WTC-A nrPDB Length = 262 Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 126/255 (49%), Gaps = 18/255 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK-YPGIQTRVLDVTKK 62 L GK+ +T AAQGIG+A AL A++GA VI D+ + L E K + R + +T Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTAD 65 Query: 63 -KQIDQF-------ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 DQF A + LD++ N AG +LD E + + ++NV+ + ++ Sbjct: 66 ISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLWGMQ 125 Query: 115 AFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 A + +K G IIN S+A +G YS TK AV LT+S A + GI Sbjct: 126 A-AATLFKEKGTKGKIINACSIAGH-EGYPLLGAYSATKFAVRALTQSAAKELASSGITV 183 Query: 173 NCVCPGTVDTP---SLQERIQARGNPE--EARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 N CPG V T ++ +R+ E +++ GR TA+++A YL+S Sbjct: 184 NSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLSSS 243 Query: 228 ESAYVTGNPVIIDGG 242 ++ Y+TG V+IDGG Sbjct: 244 DADYMTGQSVLIDGG 258 >1GEG-A nrPDB Length = 256 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 84/251 (33%), Positives = 122/251 (48%), Gaps = 16/251 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTRV-LDVTK 61 KV ++T A QGIG+A AL ++G V D N++ + E+ + G V +DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 62 KKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + Q+ +Q + DV+ N AG + + D N+NV+ + I+A + Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAAV 122 Query: 118 PKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 + G IIN S A V G VYS++K AV GLT++ A D GI N C Sbjct: 123 EAFKKEGHGGKIINACSQAGHV-GNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 177 PGTVDTPSLQE----RIQARGNP-EEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 PG V TP E +A G P +F KR GR + E++A YLAS +S Y Sbjct: 182 PGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDY 241 Query: 232 VTGNPVIIDGG 242 +TG ++IDGG Sbjct: 242 MTGQSLLIDGG 252 >4RZH-A nrPDB Length = 247 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 84/253 (33%), Positives = 130/253 (51%), Gaps = 21/253 (8%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKYPGIQTR 55 M L +V ++T A++GIG+A ALA A G KV+ ++ ++ + E+ G Sbjct: 1 MTALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIA 60 Query: 56 V-LDVTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 V +V ++DQ ++ R+DVL N AG +L + +DW ++LN+ ++ Sbjct: 61 VQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVF 120 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 L KA ML QKSG IIN++SVA + G + YS KA VIG TK+VA + +G+ Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVA-GMMGNPGQANYSAAKAGVIGFTKTVAKELASRGV 179 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE-S 229 N V PG + T + E + A L+ R+ EE+A +LA+D + Sbjct: 180 TVNAVAPGFIAT-DMTENLNAE--------PILQFIPLARYGQPEEVAGTIRFLATDPAA 230 Query: 230 AYVTGNPVIIDGG 242 AY+TG +DGG Sbjct: 231 AYITGQTFNVDGG 243 >2PH3-A nrPDB Length = 245 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 54/180 (30%), Positives = 100/180 (55%), Gaps = 7/180 (3%) Query: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124 + Q A + LD L N AG ++ +++DW+ + N+ +++ + + M+ + Sbjct: 71 VHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTREAVKLMMKAR 130 Query: 125 SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPS 184 G I+N++SV + G + Y +KA +IG T++VA ++ Q+GI N V PG ++T Sbjct: 131 FGRIVNITSVVG-ILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVAPGFIET-E 188 Query: 185 LQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWS 244 + ER+ P+E + +LK+ GRF EE+A +L S+++ Y+TG + +DGG + Sbjct: 189 MTERL-----PQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCVDGGLT 243 >2ZAT-A nrPDB Length = 260 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 129/252 (51%), Gaps = 21/252 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L+ KV ++TA+ GIG A A A++GA V+ + + + +Q L VT Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDR--TVATLQGEGLSVTGTV 69 Query: 64 QIDQFANEVERL-----------DVLF-NVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 A + ERL D+L N A G ++D E+ WD +++NV++ L Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVL 129 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 M KA +P+M + G+++ +SSV + N Y+ +K A++GLTK++A + + IR Sbjct: 130 MTKAVVPEMEKRGGGSVLIVSSVG-AYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIR 188 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQ-KTGRFATAEEIAMLCVYLASDESA 230 NC+ PG + T Q ++AR +++K + R E+ A + +L S++++ Sbjct: 189 VNCLAPGLIKTNFSQVLWM-----DKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDAS 243 Query: 231 YVTGNPVIIDGG 242 Y+TG V++ GG Sbjct: 244 YITGETVVVGGG 255 >3O4R-A nrPDB Length = 261 Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 135/254 (53%), Gaps = 25/254 (9%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK-YPGIQTRVLDVTKK 62 L KV ++TA+ GIG A A A++GA V+ ++ K Q +++ +Q L VT Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVV---VSSRKQQNVDQAVATLQGEGLSVTGT 69 Query: 63 KQIDQFANEVERL-----------DVLF-NVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 A + ERL D+L N A G+++D E+ WD ++++NV++ Sbjct: 70 VCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPA 129 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVA--SSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 LM KA +P+M + G+++ +SS+A S G Y+ +K A++GLTK++A + + Sbjct: 130 LMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF---SPYNVSKTALLGLTKTLAIELAPR 186 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 IR NC+ PG + T S + EE+ + L+ ++ G E+ A + +L S++ Sbjct: 187 NIRVNCLAPGLIKT-SFSRMLWMDKEKEESMKETLRIRRLGE---PEDCAGIVSFLCSED 242 Query: 229 SAYVTGNPVIIDGG 242 ++Y+TG V++ GG Sbjct: 243 ASYITGETVVVGGG 256 >2EW8-A nrPDB Length = 249 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 123/251 (49%), Gaps = 20/251 (7%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-----NESKLQELEKYPGIQTRVL 57 RL K+ ++T A GIG+A A FA EGA + D+ E+ ++ L + + T Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRR--VLTVKC 61 Query: 58 DVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DV++ ++ F +V R D+L N AG + + W + +NV S +LM Sbjct: 62 DVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMA 121 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 KAF+P M G IIN++S +K + Y +TKAA IG T+++A+D + GI N Sbjct: 122 KAFVPGMKRNGWGRIINLTSTTYWLK-IEAYTHYISTKAANIGFTRALASDLGKDGITVN 180 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKR--QKTGRFATAEEIAMLCVYLASDESAY 231 + P V T + + + A D L Q R ++ +LASD++++ Sbjct: 181 AIAPSLVRTATTE------ASALSAMFDVLPNMLQAIPRLQVPLDLTGAAAFLASDDASF 234 Query: 232 VTGNPVIIDGG 242 +TG + +DGG Sbjct: 235 ITGQTLAVDGG 245 >2BGM-A nrPDB Length = 278 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 129/255 (50%), Gaps = 17/255 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG----IQTRVLD 58 RL KV I+T A GIG+ A F R GAKV+ DI + Q++ G I D Sbjct: 13 RLQDKVAIITGGAGGIGETTAKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCD 72 Query: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHHG--TVLDCEEKDWDFSMNLNVRSMYLM 112 VTK + + + +LD++F G + ++L+ +D+ M++NV +L+ Sbjct: 73 VTKDEDVRNLVDTTIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLV 132 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 K M+ K G+I+ +S++S G VY+ TK AV+GLT S+ + + GIR Sbjct: 133 AKHAARVMIPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRV 192 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKT---GRFATAEEIAMLCVYLASDES 229 NCV P V +P L + + +R + L Q G AE++A YLA DES Sbjct: 193 NCVSPYIVASPLLTDVFGV----DSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDES 248 Query: 230 AYVTGNPVIIDGGWS 244 YV+G ++IDGG++ Sbjct: 249 KYVSGLNLVIDGGYT 263 >4CR6-A nrPDB Length = 271 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 80/264 (30%), Positives = 117/264 (44%), Gaps = 36/264 (13%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE----SKLQELEKYPGIQTRVL 57 GRL GK I+T AA GIG+A A+ REGA V+A D+ ++ +E P Sbjct: 11 GRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGAIPIACDLAD 70 Query: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGT--VLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + LD+L G + GT LD + DWD +++N+ +L +A Sbjct: 71 RAAIDAAMADAVARLGGLDILV-AGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRA 129 Query: 116 FLPKMLAQKSGN------IINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 M+A +G II + SV +S Y K V LT+++A D + G Sbjct: 130 GARAMVAAGAGKDGRSARIITIGSV-NSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHG 188 Query: 170 IRCNCVCPGTVDT---------PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAML 220 I N + PG VD P L E++ L GR EE+A Sbjct: 189 ILVNMIAPGPVDVTGNNTGYSEPRLAEQV-------------LDEVALGRPGLPEEVATA 235 Query: 221 CVYLASDESAYVTGNPVIIDGGWS 244 V+LA D S+++TG+ + IDGG S Sbjct: 236 AVFLAEDGSSFITGSTITIDGGLS 259 >3WYE-A nrPDB Length = 256 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 80/251 (31%), Positives = 127/251 (50%), Gaps = 16/251 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTRV-LDVTK 61 KV ++T A QGIG+A AL ++G V D N++ + E+ + G V +DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 62 KKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + Q+ +Q + DV+ N AG +L+ E+D ++NV S++ I+A + Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAAV 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 + G I ++ ++++G YSTTK AV GLT++ A D GI N CP Sbjct: 123 EAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYCP 182 Query: 178 GTVDTPSLQERIQAR-----GNP-EEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 G V T + E+I A G P E ++ GR + E++A L +LAS +S Y Sbjct: 183 GIVGT-GMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSDY 241 Query: 232 VTGNPVIIDGG 242 +TG ++IDGG Sbjct: 242 MTGQSLLIDGG 252 >4IS3-A nrPDB Length = 268 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 81/256 (31%), Positives = 123/256 (48%), Gaps = 22/256 (8%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKV-----IATDINESKLQELEKYPGIQTR 55 M + KV I+T +GIG AAA F GAKV +++ + Q E YP + Sbjct: 20 MNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYP--EEE 77 Query: 56 VL----DVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 VL D+T + + Q A + RLDV+ N AG + E+++ M++NV Sbjct: 78 VLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVT 137 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 ++ M K G IIN +SV + + G ++ Y +KA+VIGLT + + I+ Sbjct: 138 GVFNGAWCAYQCMKDAKKGVIINTASV-TGIFGSLSGVGYPASKASVIGLTHGLGREIIR 196 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 + IR V PG V+T GNP E +LK R EEIA + ++LASD Sbjct: 197 KNIRVVGVAPGVVNTD------MTNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASD 250 Query: 228 ESAYVTGNPVIIDGGW 243 ++ +T V +DG + Sbjct: 251 LASGITATTVSVDGAY 266 >4RZI-B nrPDB Length = 240 Score = 100 bits (248), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 81/248 (32%), Positives = 121/248 (48%), Gaps = 27/248 (10%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL----DV 59 L+ KVI++T +GIG A GAKV TD+ G T L +V Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATD---------GGNTEALGVVANV 56 Query: 60 TKKKQIDQFANEV-ERLDVLFNV---AGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T + + A E+ ++L ++ V AG DWD +N+N++ + IK Sbjct: 57 TDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKP 116 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 F+ M +K+G+I+ +SS+ S +G V + YS TKA VIG+ KS+A + + G+R N V Sbjct: 117 FIEGMYERKAGSIVAISSI-SGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAV 175 Query: 176 CPGTVDTP-SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD-ESAYVT 233 PG +DT +L R E+ R K RF EEIA +L S S+YVT Sbjct: 176 APGFIDTEMTLAIR-------EDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVT 228 Query: 234 GNPVIIDG 241 G + ++G Sbjct: 229 GEVLRVNG 236 >5JS6-A nrPDB Length = 274 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 73/229 (31%), Positives = 112/229 (48%), Gaps = 13/229 (5%) Query: 25 AFAREGAKVIATDINESKLQELEK-YPGIQTRVLDVTKKKQIDQFANEV----ERLDVLF 79 AF GA+V+ D +ES + LE+ PG + DVT++ + +E RLD + Sbjct: 30 AFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVV 89 Query: 80 NVAGFVHHGTVLDCEE---KDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136 N AG HH EE + + + LN+ Y + K LP L + GN+IN+SS+ Sbjct: 90 NNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALP-YLRKSQGNVINISSLVG 146 Query: 137 SVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPE 196 ++ G Y TK AV +TK++A D G+R NC+ PG + TP +E +P Sbjct: 147 AI-GQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPR 205 Query: 197 EARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + Q GR E+ V+LAS E+ + TG +++ GG L Sbjct: 206 ATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 253 >1HXH-A nrPDB Length = 253 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 79/246 (32%), Positives = 127/246 (51%), Gaps = 11/246 (4%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVT 60 RL GKV ++T A G+G EGAKV +DINE+ Q+L G ++ + DV+ Sbjct: 3 RLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVS 62 Query: 61 KKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + V+R L+VL N AG + G + +D+ + +N S+++ + Sbjct: 63 SEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQG 122 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG--IRCNC 174 + M + G+IINM+SV+S + + YS +KAAV LT++ A +QG IR N Sbjct: 123 IAAM-KETGGSIINMASVSSWLP-IEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNS 180 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + P + TP +Q + + E +D K + GR E IA L ++LASDES+ ++G Sbjct: 181 IHPDGIYTPMMQASLPKGVSKEMVLHDP-KLNRAGRAYMPERIAQLVLFLASDESSVMSG 239 Query: 235 NPVIID 240 + + D Sbjct: 240 SELHAD 245 >3V2G-A nrPDB Length = 271 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 122/249 (48%), Gaps = 19/249 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-----LQELEKYPGIQTRV-L 57 L GK +T ++GIG A A A EGA V T +N ++ + E+E+ G + Sbjct: 29 LAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIRA 88 Query: 58 DVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 D + I+Q E + LD+L N AG H + + D+D M +N R+ ++ I Sbjct: 89 DNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFVAI 148 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 ++ + G II + S + + +YS +KAA+ GLTK +A D +GI N Sbjct: 149 RSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGITVN 206 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG+ DT + A G+ EA+ + R TG + ++IA L +LA + +VT Sbjct: 207 IVHPGSTDT----DMNPADGDHAEAQRE---RIATGSYGEPQDIAGLVAWLAGPQGKFVT 259 Query: 234 GNPVIIDGG 242 G + IDGG Sbjct: 260 GASLTIDGG 268 >4K6F-A nrPDB Length = 255 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 71/249 (28%), Positives = 120/249 (48%), Gaps = 22/249 (8%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIAT-DINESKL-----------QELEKYPGIQT 54 ++ ++T G+G+A ++ G +V+ T N + +E YP Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYP---V 68 Query: 55 RVLDVTKKKQ-IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 V D +Q I++ +V +D+L N AG T+ ++ +WD + N+ S++ M Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT 128 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 K M+ + G I+N+SSV S KG V + Y+ KA + G TKS+A + ++G+ N Sbjct: 129 KPVCDGMVERGWGRIVNISSVNGS-KGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVN 187 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + T + Q + L + GR EE+A L YL S+E+ +VT Sbjct: 188 TVSPGYLATKMVTAIPQ-----DILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVT 242 Query: 234 GNPVIIDGG 242 G+ + I+GG Sbjct: 243 GSNIAINGG 251 >2NM0-A nrPDB Length = 253 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 70/243 (28%), Positives = 119/243 (48%), Gaps = 17/243 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A AFA G KV T + E G D+T +Q++ Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAIT------YRSGEPPEGFLAVKCDITDTEQVE 75 Query: 67 QFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 Q E+E ++VL AG ++ E+D+ + N+ + ++K ML Sbjct: 76 QAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLR 135 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 K G ++ +SSV + G + Y+ +KA ++G +S+A + + I N V PG VDT Sbjct: 136 AKKGRVVLISSVVG-LLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVDT 194 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + +E R + + + GR+A EEIA +LASD+++Y+TG + +DGG Sbjct: 195 DMTKVLT------DEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGG 248 Query: 243 WSL 245 + Sbjct: 249 LGM 251 >2CDH-G nrPDB Length = 244 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 71/249 (28%), Positives = 122/249 (48%), Gaps = 18/249 (7%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQ-TRVLDVTK 61 V+++T A++GIG+A AL+ + G KV+ +K E +E Y G T DV+K Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + ++ +DV+ N AG ++ ++ WD ++LN+ ++L +A Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G IIN++SV + G + + Y+ KA VIG +K+ A + + I N VCP Sbjct: 123 KIMMKKRKGRIINIASVVGLI-GNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA-SDESAYVTGNP 236 G + + + E+ L GR E +A L +LA S ++Y+TG Sbjct: 182 GFIASDMTAKL------GEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQA 235 Query: 237 VIIDGGWSL 245 IDGG ++ Sbjct: 236 FTIDGGIAI 244 >6NRP-A nrPDB Length = 263 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 125/246 (50%), Gaps = 23/246 (9%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTRVL--DVTK 61 I++T +++GIG+A AL A+ G V + E +QE++ G + L DV + Sbjct: 27 ILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQAL-GQNSHYLMFDVNE 85 Query: 62 KKQIDQ-FANEVERLDVLFNV---AGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF- 116 ++ + Q +VE+ + V AG H G ++DWD ++ ++ Y ++K Sbjct: 86 RQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPLI 145 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 +P + +K G I+ +SSV S + G + YS KA +IG TK++A + ++ I NCV Sbjct: 146 MPMIHLRKGGRIVTLSSV-SGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 PG ++T + +E + LK R +E+A + +L SDE++YVT Sbjct: 205 PGLIETEMV---------TDEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQV 255 Query: 237 VIIDGG 242 + ++GG Sbjct: 256 ISVNGG 261 >5B1Y-A nrPDB Length = 270 Score = 96.7 bits (239), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 65/202 (32%), Positives = 101/202 (50%), Gaps = 20/202 (9%) Query: 10 ILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKY--PGIQTRVLDVTKK 62 ++T ++GIG+A L FAREG V+ D+ E +E + P T +DV Sbjct: 27 LVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGDP 86 Query: 63 KQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 + + ++ V L+VL N AG + G + + +W+ ++ +N+ +YL+ K LP Sbjct: 87 DSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTKLLLP 146 Query: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPG 178 + K +I+N++S+A VV YS +KA VIGLTK +A GIR N V P Sbjct: 147 LLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAPS 206 Query: 179 TV---------DTPSLQERIQA 191 V DTP +ERI + Sbjct: 207 FVETDMTRSFLDTPEKRERIAS 228 >1O5I-A nrPDB Length = 249 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 70/244 (28%), Positives = 128/244 (52%), Gaps = 13/244 (5%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 +G D V++L AA++GIG+A A ++EGA+V NE EL K G + V D+ Sbjct: 15 LGIRDKGVLVL-AASRGIGRAVADVLSQEGAEVTICARNE----ELLKRSGHRYVVCDL- 68 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 +K +D +V+ +D+L AG G + +D+ +++ +M +++ +LP M Sbjct: 69 -RKDLDLLFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPAM 127 Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 + G I+ ++S S + + N ++ + A+ G K+++ + GI NCV PG Sbjct: 128 KEKGWGRIVAITSF-SVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWT 186 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 +T ++E + EE + + R A EEIA + +L S++++Y+TG +++D Sbjct: 187 ETERVKELLS-----EEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVD 241 Query: 241 GGWS 244 GG S Sbjct: 242 GGLS 245 >1CYD-A nrPDB Length = 244 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 123/236 (52%), Gaps = 7/236 (2%) Query: 10 ILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY-PGIQTRVLDVTKKKQIDQF 68 ++T A +GIG+ A GAKV+A S L L K PGI+ +D+ ++ Sbjct: 11 LVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDATEKA 70 Query: 69 ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK-SGN 127 + +D+L N A V L+ ++ +D S ++N+RS++ + + M+ + G+ Sbjct: 71 LGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRGVPGS 130 Query: 128 IINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQE 187 I+N+SS+ + V N YS+TK A+ LTK++A + IR N V P V T + + Sbjct: 131 IVNVSSMVAHVT-FPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLT-DMGK 188 Query: 188 RIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGW 243 ++ A +PE AR +R +FA E++ ++L SD SA +G +++D G+ Sbjct: 189 KVSA--DPEFARK-LKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAGY 241 >3UN1-A nrPDB Length = 260 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 66/248 (26%), Positives = 121/248 (48%), Gaps = 22/248 (8%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 M R KV+++T A+QGIG A+ +V+AT S+ + P I T D++ Sbjct: 23 MMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVAT----SRSIKPSADPDIHTVAGDIS 78 Query: 61 KKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 K + D+ E R+D L N AG ++ ++D+D ++ +NV + + + Sbjct: 79 KPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRA 138 Query: 117 LPKMLAQKSGNIINMSS--VASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 +ML Q SG+I+++++ V + G+ + + S TK + +T+S+A +F + G+R N Sbjct: 139 AAEMLKQGSGHIVSITTSLVDQPMVGMPS-ALASLTKGGLNAVTRSLAMEFSRSGVRVNA 197 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG + TP +P E + GR ++ +YL + + ++TG Sbjct: 198 VSPGVIKTPM---------HPAETHSTLAGLHPVGRMGEIRDVVDAVLYL--EHAGFITG 246 Query: 235 NPVIIDGG 242 + +DGG Sbjct: 247 EILHVDGG 254 >6CI9-A nrPDB Length = 259 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 70/255 (27%), Positives = 118/255 (46%), Gaps = 23/255 (9%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL-QELEKYPGIQTRVL----D 58 L+G+ I+T ++GIG+ A FA G V+ T N+ L + + G + +V D Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRAD 66 Query: 59 VTKKKQIDQ-FANEVER---LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 VT + + A V R LD++ AG G + D D + + +N + +++ Sbjct: 67 VTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQ 126 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 A L + A G ++ SS+ + G Y +KAA +G ++ A + + I N Sbjct: 127 AALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINA 186 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKT----GRFATAEEIAMLCVYLASDESA 230 V PG + T L E Q D+L + + GR + +I ++ A+DE+A Sbjct: 187 VLPGNIMTEGLDEMGQ----------DYLDQMASAIPAGRLGSVADIGNAALFFATDEAA 236 Query: 231 YVTGNPVIIDGGWSL 245 YVTG +++DGG L Sbjct: 237 YVTGQTLVVDGGQVL 251 >4CQM-B nrPDB Length = 244 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 70/246 (28%), Positives = 123/246 (50%), Gaps = 20/246 (8%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAK--VIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 KV + ++GIG+A A AR+G + VIA ++ +K + DV K+ Sbjct: 10 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 69 Query: 65 IDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 + E+E R++ L N AG G ++ + +D ++ N+ L KA + M Sbjct: 70 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 129 Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 + Q+ G+I+N+ S+ +KG + VYS +K ++G ++++A + ++ IR N V PG V Sbjct: 130 IQQQGGSIVNVGSIVG-LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 188 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQ-KTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 T ++ + + LK+ GRF E+A V+L ES Y+TG+ +++ Sbjct: 189 HTDM----------TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 236 Query: 240 DGGWSL 245 DGG L Sbjct: 237 DGGLQL 242 >5VT6-A nrPDB Length = 269 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 54/172 (31%), Positives = 94/172 (54%), Gaps = 6/172 (3%) Query: 74 RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSS 133 ++DVL N AG T + + DWD M ++ +M+ + K F+ M+ ++ G I+N+ S Sbjct: 103 KVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQFIAGMVERRFGRIVNIGS 162 Query: 134 VASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARG 193 V S +G + Y++ KA + G TK++A + ++GI N V PG + T ++ Q Sbjct: 163 VNGS-RGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTVSPGYLATAMVEAVPQ--- 218 Query: 194 NPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + EA+ L + GR +E+A L +L SD++ +VTG + I+GG + Sbjct: 219 DVLEAK--ILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLAINGGMHM 268 >3T7C-A nrPDB Length = 299 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 70/272 (25%), Positives = 126/272 (46%), Gaps = 31/272 (11%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-------------NESKLQELEK 48 G+++GKV +T AA+G G++ A+ AREGA +IA D+ + + + + Sbjct: 24 GKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQ 83 Query: 49 YPGIQTRVL----DV----TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLD-CEEKDWD 99 + R++ DV + +D ++ RLD++ A GT L+ + K W Sbjct: 84 VEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWR 143 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159 +++N+ ++ + +P ++A K G I +S ++G N Y +K + GL + Sbjct: 144 DMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMR 203 Query: 160 SVAADFIQQGIRCNCVCPGTVDTPSLQERIQAR------GNPEEARNDFLKRQK---TGR 210 ++A + + IR N VCP +V TP L R NP RQ Sbjct: 204 TMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIP 263 Query: 211 FATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + +I+ ++L SD++ Y+TG + +DGG Sbjct: 264 YVEPADISNAILFLVSDDARYITGVSLPVDGG 295 >5OVL-A nrPDB Length = 300 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 72/246 (29%), Positives = 123/246 (50%), Gaps = 23/246 (9%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A A +G KV T +L G+Q DVT +D Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLF---GVQ---CDVTDSAAVD 122 Query: 67 QFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + EVE ++VL AG ++ E+ ++ +N N+ + + M Sbjct: 123 RAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQR 182 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 ++ G II + SV S + G+ N+ Y+ KA +IG+ +S++ + + G+ N V PG +DT Sbjct: 183 KRFGRIIFIGSV-SGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDT 241 Query: 183 P---SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 +L ERIQA DF+ ++ G TAEE+A +LAS++++Y+ G + + Sbjct: 242 EMTRALDERIQA------GALDFIPAKRVG---TAEEVAGAVSFLASEDASYIAGAVIPV 292 Query: 240 DGGWSL 245 DGG + Sbjct: 293 DGGMGM 298 >5OVJ-A nrPDB Length = 256 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 72/246 (29%), Positives = 123/246 (50%), Gaps = 23/246 (9%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A A +G KV T +L G+Q DVT +D Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLF---GVQ---CDVTDSAAVD 78 Query: 67 QFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + EVE ++VL AG ++ E+ ++ +N N+ + + M Sbjct: 79 RAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQR 138 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 ++ G II + SV S + G+ N+ Y+ KA +IG+ +S++ + + G+ N V PG +DT Sbjct: 139 KRFGRIIFIGSV-SGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDT 197 Query: 183 P---SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 +L ERIQA DF+ ++ G TAEE+A +LAS++++Y+ G + + Sbjct: 198 EMTRALDERIQA------GALDFIPAKRVG---TAEEVAGAVSFLASEDASYIAGAVIPV 248 Query: 240 DGGWSL 245 DGG + Sbjct: 249 DGGMGM 254 >2AE2-A nrPDB Length = 260 Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 121/251 (48%), Gaps = 16/251 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL-----QELEKYPGIQTRVLD 58 L+G ++T ++GIG A GA V N+ +L Q K ++ V D Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCD 66 Query: 59 VTKKKQIDQFANEVE-----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 ++ + + + N V +L++L N AG V + D +D+ M++N + Y + Sbjct: 67 LSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLS 126 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 P + A + GN++ +SSV+ ++ V VY TK A+ LT+ +A ++ + IR N Sbjct: 127 VLAHPFLKASERGNVVFISSVSGAL-AVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVN 185 Query: 174 CVCPGTVDTPSLQERIQARGNPE--EARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 V PG + T ++ IQ +PE E N + R R +E+A + +L ++Y Sbjct: 186 GVGPGVIATSLVEMTIQ---DPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASY 242 Query: 232 VTGNPVIIDGG 242 VTG + +DGG Sbjct: 243 VTGQIIYVDGG 253 >3UVE-A nrPDB Length = 286 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 76/279 (27%), Positives = 125/279 (44%), Gaps = 35/279 (12%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-----------------NESKLQ 44 GR++GKV +T AA+G G++ A+ A+EGA +IA DI E + Sbjct: 7 GRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAE 66 Query: 45 ELEKYPGIQTRVL----DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLD-CEE 95 + G R++ DV K +D ++ RLD++ AG + G LD E Sbjct: 67 TADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSE 126 Query: 96 KDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVI 155 +DW +++N+ ++ +KA +P M+A G I ++S +K + Y K V+ Sbjct: 127 EDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVV 186 Query: 156 GLTKSVAADFIQQGIRCNCVCPGTVDTPSLQER---------IQARGNPEEARNDFLKRQ 206 GL ++ + Q IR N V P V TP L ++ G + A + Sbjct: 187 GLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHT 246 Query: 207 KTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + +I+ ++ ASDE+ Y+TG + ID G L Sbjct: 247 LPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >3D3W-A nrPDB Length = 244 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 70/242 (28%), Positives = 121/242 (50%), Gaps = 7/242 (2%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-EKYPGIQTRVLDVTKK 62 L G+ +++T A +GIG+ A GA+V+A ++ L L + PGI+ +D+ Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDW 64 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + ++ V +D+L N A L+ ++ +D S +N+R++ + + ++A Sbjct: 65 EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIA 124 Query: 123 QK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVD 181 + G I+N+SS S + V N VY +TK A+ LTK +A + IR N V P V Sbjct: 125 RGVPGAIVNVSSQCSQ-RAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVM 183 Query: 182 TPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDG 241 T Q +P +A+ L R G+FA E + ++L SD S TG+ + ++G Sbjct: 184 TSMGQ---ATWSDPHKAKT-MLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEG 239 Query: 242 GW 243 G+ Sbjct: 240 GF 241 >4DBZ-A nrPDB Length = 281 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 124/259 (47%), Gaps = 19/259 (7%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE----SKLQELEKYPGIQT-- 54 M D +V ++T A GIG A +EG +V E + L+EL + G++ Sbjct: 21 MATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKEL-REAGVEADG 79 Query: 55 RVLDVTKKKQIDQF-ANEVER---LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 R DV +I+ A VER +DVL N AG G + ++ W + N+ ++ Sbjct: 80 RTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVF 139 Query: 111 LMIKAFLPK--MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 + K L ML + +G I+N++S +G+V+ YS +K V+G TK++ + + Sbjct: 140 RVTKQVLKAGGMLERGTGRIVNIASTGGK-QGLVHAAPYSASKHGVVGFTKALGLELART 198 Query: 169 GIRCNCVCPGTVDTP---SLQERIQA--RGNPEEARNDFLKRQKTGRFATAEEIAMLCVY 223 GI N VCPG V+TP S++E + EEA + R GR+ E+A + Y Sbjct: 199 GITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAY 258 Query: 224 LASDESAYVTGNPVIIDGG 242 L +A VT + + GG Sbjct: 259 LIGPGAAAVTAQALNVCGG 277 >3RWB-A nrPDB Length = 247 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 120/248 (48%), Gaps = 15/248 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVT 60 RL GK ++T AAQGIG+A A A +GA VI +DIN + G + R + D++ Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADIS 62 Query: 61 KKKQIDQFANEVERL----DVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + E++ L D+L N A V D + W +++N+ +++ +A Sbjct: 63 DPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRAG 122 Query: 117 LPKM-LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +M A K+G +I+++S + G N Y K VIG T+++A + + I N V Sbjct: 123 TDQMRAAGKAGRVISIAS-NTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAV 181 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKR-QKTGRFATAEEIAMLCVYLASDESAYVTG 234 PG +++ + + +P F++ Q E IA + +LASD++ ++TG Sbjct: 182 TPGLIESDGV------KASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARWITG 235 Query: 235 NPVIIDGG 242 + +D G Sbjct: 236 QTLNVDAG 243 >4EGF-A nrPDB Length = 266 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/254 (29%), Positives = 131/254 (51%), Gaps = 16/254 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG------IQTRV 56 RLDGK ++T A +GIG A AFA GA+++ + + S+L + G + T Sbjct: 17 RLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVA 76 Query: 57 LDVTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +D+ + + A LDVL N AG H V+D + + +D ++ +N+R+ L+ Sbjct: 77 IDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALL 136 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 A M+A G I + A+++ + + Y T+KA ++ TK +A + GIR Sbjct: 137 ASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRA 196 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARN-DFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 N VCP V T + +R+ +EA++ + R GRFA E++ V+LASD ++ Sbjct: 197 NSVCPTVVLT-EMGQRVWG----DEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASM 251 Query: 232 VTGNPVIIDGGWSL 245 + G + +DGG+++ Sbjct: 252 INGVDIPVDGGYTM 265 >4IIV-A nrPDB Length = 267 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/247 (29%), Positives = 120/247 (48%), Gaps = 19/247 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKV-IATDINESKLQELEKY---PGIQTRVL--DVT 60 + +++T A++GIG+A A A +G + + + + QE G R+L DV Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVA 86 Query: 61 KKKQIDQ-FANEVERLDVLFNV---AGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA- 115 ++Q + +E+ + + V AG DWD ++ N+ S Y +I+ Sbjct: 87 NREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQPC 146 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +P + A++ G II +SSV S V G + YS KA +IG TK++A + ++ I NC+ Sbjct: 147 IMPMIGARQGGRIITLSSV-SGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCI 205 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG +DT ++ E A + + R AEE+A L YL SD + YVT Sbjct: 206 APGLIDTGMIEME-------ESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQ 258 Query: 236 PVIIDGG 242 + I+GG Sbjct: 259 VISINGG 265 >3VZS-A nrPDB Length = 257 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 113/246 (45%), Gaps = 17/246 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA----TDINESKLQELEKYPGI-----QTRVL 57 ++ +T GIG A A++G +V+A K E +K G + V Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 58 DV-TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 D + K D+ +EV +DVL N AG DWD ++ N+ S++ + K Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQV 134 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 + M + G I+N+SSV + KG + YST KA + G T ++A + +G+ N V Sbjct: 135 IDGMADRGWGRIVNISSV-NGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVS 193 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 PG + T ++ Q + + + R EEIA +C +L+S+ES + TG Sbjct: 194 PGYIATDMVKAIRQ------DVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGAD 247 Query: 237 VIIDGG 242 ++GG Sbjct: 248 FSLNGG 253 >3AUT-A nrPDB Length = 269 Score = 90.5 bits (223), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 75/255 (29%), Positives = 128/255 (50%), Gaps = 22/255 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN--ESKL---QELEKYPGIQTRVL- 57 L KV+++T + G+G+A A+ F +E AKV+ N E L +E+E+ G V Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQG 72 Query: 58 DVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL-- 111 DVTK++ + E LDV+ N AG + + +W+ ++ N+ +L Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGS 132 Query: 112 --MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 IK F+ + GN+INMSSV + + Y+ +K + +T+++A ++ +G Sbjct: 133 REAIKYFVENDI---KGNVINMSSVHEMIPWPL-FVHYAASKGGMKLMTETLALEYAPKG 188 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 IR N + PG ++TP E+ +P + R D G EE+A + +LAS ++ Sbjct: 189 IRVNNIGPGAMNTPINAEKF---ADPVQ-RADVESMIPMGYIGKPEEVAAVAAFLASSQA 244 Query: 230 AYVTGNPVIIDGGWS 244 +YVTG + DGG + Sbjct: 245 SYVTGITLFADGGMT 259 >4TRR-A nrPDB Length = 269 Score = 90.5 bits (223), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 76/264 (28%), Positives = 125/264 (47%), Gaps = 27/264 (10%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTRV 56 M L+GK ++T AA GIG+ AL A+ GA V D+N+ E+ K G V Sbjct: 9 MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGV 68 Query: 57 -LDVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 +DVT ++ ID+ A +D+L + AG + + DW ++V +L Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFL 128 Query: 112 MIKAFLPKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 KA L M + G +I M SV S + + Y T K ++GL + +A + + + Sbjct: 129 TTKAALKHMYKDDRGGVVIYMGSVHSHEASPL-KSAYVTAKHGLLGLARVLAKEGAKHNV 187 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKT-----------GRFATAEEIAM 219 R + VCPG V TP + ++I PE+A+ + ++ G F T +++A Sbjct: 188 RSHVVCPGFVRTPLVDKQI-----PEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQ 242 Query: 220 LCVYLASDESAYVTGNPVIIDGGW 243 ++L++ SA +TG I+ GW Sbjct: 243 TVLFLSAFPSAALTGQSFIVSHGW 266 >2GDZ-A nrPDB Length = 267 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 72/204 (35%), Positives = 109/204 (53%), Gaps = 35/204 (17%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQ---------ELEKYPGIQ 53 ++GKV ++T AAQGIG+A A A +GAKV D N E+ +Q E +K IQ Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 54 TRVLDV-----TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRS 108 V D T +K +D F RLD+L N AG EK+W+ ++ +N+ S Sbjct: 65 CDVADQQQLRDTFRKVVDHFG----RLDILVNNAGV--------NNEKNWEKTLQINLVS 112 Query: 109 M----YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS--VA 162 + YL + ++ K + G IINMSS+A + V + VY +K ++G T+S +A Sbjct: 113 VISGTYLGLD-YMSKQNGGEGGIIINMSSLAGLMP-VAQQPVYCASKHGIVGFTRSAALA 170 Query: 163 ADFIQQGIRCNCVCPGTVDTPSLQ 186 A+ + G+R N +CPG V+T L+ Sbjct: 171 ANLMNSGVRLNAICPGFVNTAILE 194 >3OEC-A nrPDB Length = 317 Score = 89.7 bits (221), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 73/272 (26%), Positives = 125/272 (45%), Gaps = 30/272 (11%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI------------NESKLQEL-- 46 M RL GKV +T AA+G G+ A+ A++GA ++A D+ + +L+E Sbjct: 41 MNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVR 100 Query: 47 ---EKYPGIQTRVLDV----TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD 99 E+ I R DV + + +D+ E +D+L + G + G V+ ++ W Sbjct: 101 LVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWS 160 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159 + N+ + +A LP M+ + G + S ++G + Y+ +K V GL Sbjct: 161 DILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLML 220 Query: 160 SVAADFIQQGIRCNCVCPGTVDTP-SLQER-----IQARGNPEEARNDFLKRQKTG---R 210 S+A + + IR N V PG V+T +L E+ + NP L Q T Sbjct: 221 SLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP 280 Query: 211 FATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + E+++ +LASDE+ Y+ G + +DGG Sbjct: 281 WVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >3A28-C nrPDB Length = 258 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 78/253 (30%), Positives = 121/253 (47%), Gaps = 18/253 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR-------VLDV 59 KV ++T AQGIG+ + A +G + D+ + + Q E I+ LDV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 60 TKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T K ID+ A ++ DVL N AG +L+ E+D ++NV S++ I+A Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 K I ++ ++++G YSTTK AV GLT++ A + +G N Sbjct: 123 ASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAY 182 Query: 176 CPGTVDTPSLQERIQAR-----GNP-EEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 PG V T + E+I A G P E ++ GR + E++A L +LAS+ S Sbjct: 183 APGIVGT-GMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENS 241 Query: 230 AYVTGNPVIIDGG 242 YVTG +++DGG Sbjct: 242 NYVTGQVMLVDGG 254 >4MOW-A nrPDB Length = 256 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 127/252 (50%), Gaps = 16/252 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTR 55 M +L GKV I+T A++GIG A A A A EGA V+ + ++ + + + G Sbjct: 9 MSKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVA 68 Query: 56 V-LDVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 V DV+K ++ +D RLDVL N +G + E+ + + NV + Sbjct: 69 VGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVL 128 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 L +A + K L + + +IIN+SSV +S+ + VYS TK AV +T +A + + I Sbjct: 129 LTTQAAV-KHLGEGA-SIINISSVVTSITPPAS-AVYSGTKGAVDAITGVLALELGPRKI 185 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESA 230 R N + PG + T G+ EA+ L + GR +IA + V+LASD++ Sbjct: 186 RVNAINPGMIVTEGTHSA-GIIGSDLEAQ--VLGQTPLGRLGEPNDIASVAVFLASDDAR 242 Query: 231 YVTGNPVIIDGG 242 ++TG +++ GG Sbjct: 243 WMTGEHLVVSGG 254 >2HSD-A nrPDB Length = 253 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 116/250 (46%), Gaps = 19/250 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV--LDVTK 61 L GK +I+T A+G+G AA GA+V+ D+ + + + G R LDVT Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTI 62 Query: 62 KKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKD-WDFSMNLNVRSMYLMIKAF 116 ++ + E +D L N AG + G L+ E + + + +N+ +++ +K Sbjct: 63 EEDWQRVVAYAREEFGSVDGLVNNAG-ISTGMFLETESVERFRKVVEINLTGVFIGMKTV 121 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 +P M G+I+N+SS A+ + G+ Y +K V GL+K A + IR N V Sbjct: 122 IPAMKDAGGGSIVNISS-AAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVH 180 Query: 177 PGTVDTPSLQER--IQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 PG TP E Q GN GR EIA V L SD S+YVTG Sbjct: 181 PGMTYTPMTAETGIRQGEGN--------YPNTPMGRVGEPGEIAGAVVKLLSDTSSYVTG 232 Query: 235 NPVIIDGGWS 244 + +DGGW+ Sbjct: 233 AELAVDGGWT 242 >2B4Q-A nrPDB Length = 276 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 116/254 (45%), Gaps = 16/254 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVI--ATDINE--SKLQELEKYPGIQTRVLDV 59 L G++ ++T ++GIGQ A GA+V A D L Y Q D+ Sbjct: 27 LAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADL 86 Query: 60 TKK---KQIDQFANEVE-RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + +++ Q E+ RLD+L N AG + W+ M LNV S++ I+ Sbjct: 87 SSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQQ 146 Query: 116 FLPKML----AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 LP + A+ +IN+ SVA Y +KAA+ L++ +A + + + I Sbjct: 147 LLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVGEHIN 206 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 N + PG PS R A +P+ D GR+ EE+A L + LA AY Sbjct: 207 VNVIAPGRF--PSRMTRHIAN-DPQALEADS-ASIPMGRWGRPEEMAALAISLAGTAGAY 262 Query: 232 VTGNPVIIDGGWSL 245 +TGN + IDGG+ L Sbjct: 263 MTGNVIPIDGGFHL 276 >3OIC-A nrPDB Length = 258 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/249 (25%), Positives = 122/249 (48%), Gaps = 15/249 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESK--LQELEKYPGIQTRVL----DVT 60 K ++T +++G+G+AAA+ A G ++ K L+ E+ + +VL +V Sbjct: 5 KCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANVG 64 Query: 61 KKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + +I + +++ RLDV N A V++ EE WD++MN+N +++ + Sbjct: 65 QPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEA 124 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 M G+I+++SS+ S++ + N +KAA+ LT+ +A + + I N V Sbjct: 125 AKLMEKNGGGHIVSISSLG-SIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVS 183 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 G +DT +L+ N E+ D + GR +++ +L S ++ + G Sbjct: 184 GGAIDTDALKH----FPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQT 239 Query: 237 VIIDGGWSL 245 +I+DGG SL Sbjct: 240 IIVDGGRSL 248 >1UZM-A nrPDB Length = 247 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 67/246 (27%), Positives = 123/246 (50%), Gaps = 23/246 (9%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A A +G KV T + L G++ +DVT +D Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLF---GVE---VDVTDSDAVD 69 Query: 67 QFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + VE ++VL + AG ++ E+ ++ +N N+ + + + M Sbjct: 70 RAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQR 129 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 K G +I + SV S + G+ N+ Y+ +KA VIG+ +S+A + + + N V PG +DT Sbjct: 130 NKFGRMIFIGSV-SGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDT 188 Query: 183 P---SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 +L ERIQ + F+ ++ G T E+A + +LAS++++Y++G + + Sbjct: 189 DMTRALDERIQ------QGALQFIPAKRVG---TPAEVAGVVSFLASEDASYISGAVIPV 239 Query: 240 DGGWSL 245 DGG + Sbjct: 240 DGGMGM 245 >1AHH-A nrPDB Length = 255 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 126/250 (50%), Gaps = 18/250 (7%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK----LQELEKYPG--IQTRV 56 RLDGK I+T A GIG+ A+ FA GA V+ +DIN + E+++ G R Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 Query: 57 LDVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 D+T ++++ A+ ++ ++D+L N AG D D+ + LNV S + + Sbjct: 68 -DITSEQELSALADFAISKLGKVDILVNNAGG-GGPKPFDMPMADFRRAYELNVFSFFHL 125 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + P+M G I+ ++S+A+ K +N Y+++KAA L +++A D ++ IR Sbjct: 126 SQLVAPEMEKNGGGVILTITSMAAENKN-INMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N + PG + T +L+ I E L+ R ++IA ++L S +++V Sbjct: 185 NGIAPGAILTDALKSVIT-----PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 Query: 233 TGNPVIIDGG 242 +G + + GG Sbjct: 240 SGQILTVSGG 249 >5T5Q-A nrPDB Length = 247 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 119/247 (48%), Gaps = 18/247 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV----LDV 59 + + ++LT A GIG+A A F GA ++ TD++ L G R+ D Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 66 Query: 60 TKKKQIDQ-FANEVER---LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + ++ A +ER +D L AG + + DW ++++N+ ++ + K Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCKR 126 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 LP + ++ +I+ ++S+A+ VN Y TK A++ +T++++ + + R N V Sbjct: 127 ALPAL--KEDSSIVTLASLAAYRGAYVN-AHYGATKGAMVSMTRALSRELAPK-TRVNGV 182 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG ++TP E ++ R ++ + + R EIA + +L S +++VTG Sbjct: 183 SPGIIETPMTSELLKTR------MDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGE 236 Query: 236 PVIIDGG 242 + ++GG Sbjct: 237 TIQVNGG 243 >3EZL-A nrPDB Length = 256 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 69/250 (27%), Positives = 112/250 (44%), Gaps = 25/250 (10%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA----TDINESKLQELEKYPGI-----QTRVL 57 ++ +T GIG + ++G +V+A K E +K G + V Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVG 73 Query: 58 DVTKKKQ-IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 D KQ D+ EV +DVL N AG +DW ++ N+ S++ + K Sbjct: 74 DWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQV 133 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 + M+ + G IIN+SSV + KG + YST KA + G T S+A + +G+ N V Sbjct: 134 IDGMVERGWGRIINISSV-NGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVS 192 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKR----QKTGRFATAEEIAMLCVYLASDESAYV 232 PG + T ++ R D L++ R + +EI + +LAS+ES + Sbjct: 193 PGYIGTDMVK----------AIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFS 242 Query: 233 TGNPVIIDGG 242 TG ++GG Sbjct: 243 TGADFSLNGG 252 >5EJ2-A nrPDB Length = 308 Score = 83.6 bits (205), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 76/276 (27%), Positives = 122/276 (44%), Gaps = 39/276 (14%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-------------------NESK 42 GR+ GKV ++ AA+G G++ A+ A+EGA +IA DI Sbjct: 33 GRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADL 92 Query: 43 LQELEKYPGIQTRVLDVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLD-CEEKD 97 +++L++ I T +DV K +D ++ RLD++ AG G L + Sbjct: 93 VKDLDRR--IVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNV 150 Query: 98 WDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGL 157 W +++N+ ++ +KA +P +L+ G I ++S K N Y K VIGL Sbjct: 151 WQDMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGL 210 Query: 158 TKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQAR------GNPEEARNDF-----LKRQ 206 ++ A + IR N V P V T + R NP +DF + Sbjct: 211 MRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENP--GPDDFAPISQMMHT 268 Query: 207 KTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + A +I+ ++LASDES YVTG + +D G Sbjct: 269 LPVPWVDASDISNAVLFLASDESRYVTGVSLPVDAG 304 >4IIN-A nrPDB Length = 271 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 125/255 (49%), Gaps = 27/255 (10%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIAT-----DINESKLQELEKYPGIQTRVL 57 + GK +++T A++GIG A A G KV ++ ++ ELE+ G + V+ Sbjct: 26 QFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEE-KGYKAAVI 84 Query: 58 DVTKKKQIDQFANEVER-------LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 + D F ++ L L N AG V + + +D+ ++ N+ S + Sbjct: 85 KFDAASESD-FIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAF 143 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 + + L M + G+++N++S+ +G + + YS +K +I ++KS A + + I Sbjct: 144 IGCREALKVMSKSRFGSVVNVASIIGE-RGNMGQTNYSASKGGMIAMSKSFAYEGALRNI 202 Query: 171 RCNCVCPGTVDT---PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 R N V PG ++T +L++ ++A D++K R +A+E+A +L SD Sbjct: 203 RFNSVTPGFIETDMNANLKDELKA---------DYVKNIPLNRLGSAKEVAEAVAFLLSD 253 Query: 228 ESAYVTGNPVIIDGG 242 S+Y+TG + ++GG Sbjct: 254 HSSYITGETLKVNGG 268 >3RKU-A nrPDB Length = 287 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/252 (30%), Positives = 124/252 (49%), Gaps = 24/252 (9%) Query: 3 RLDGKVIILTAAAQGIGQAAALAF--AREG-AKVIATDINESKLQELEK-----YPGIQT 54 RL K +++T A+ GIG+A AL + A G K+I KL+EL+K +P + Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 55 RV--LDVTKKKQIDQF----ANEVERLDVLFNVAG-FVHHGTVLDCEEKDWDFSMNLNVR 107 V LD+T+ ++I F E + +D+L N AG + V +D + NV Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 ++ + +A LP A+ SG+I+N+ S+A +Y +K AV T S+ + I Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGR-DAYPTGSIYCASKFAVGAFTDSLRKELIN 208 Query: 168 QGIRCNCVCPGTVDTP-SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 IR + PG V+T SL ++ RGN E+A+N + K A+++A L VY S Sbjct: 209 TKIRVILIAPGLVETEFSL---VRYRGNEEQAKNVY----KDTTPLMADDVADLIVYATS 261 Query: 227 DESAYVTGNPVI 238 + V + +I Sbjct: 262 RKQNTVIADTLI 273 >5JY1-A nrPDB Length = 274 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 86/262 (32%), Positives = 124/262 (47%), Gaps = 28/262 (10%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK----LQELEKYPGIQTRV 56 MG L+ +V ++T A GIG+ A +F EGA VI +INES QE+ + G V Sbjct: 9 MGLLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFV 68 Query: 57 -LDVTKKKQI--------DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 DVT K I +QF + LD+L N A FV VL E+ D L Sbjct: 69 KTDVTSKASIEAAVRSAVEQFGS----LDILVNNA-FVPTPNVLLEEKTDEMLEQTLTTS 123 Query: 108 ---SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 + + M AF+P M ++ G I+N S+ + G Y+T KA ++GLT+S A++ Sbjct: 124 LWATWWAMRAAFVP-MRERRWGRIVNFYSIDTET-GAWLHGDYNTAKAGIVGLTRSAASE 181 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEE-IAMLCVY 223 + + I N + P + + A NPE A R GR E+ I V+ Sbjct: 182 WGRFNITVNAIAPTAMGATFFE---LAAKNPEFAERSAAAR-PLGRSGDPEQDIGPAAVF 237 Query: 224 LASDESAYVTGNPVIIDGGWSL 245 AS+ S +VTG + +DGG L Sbjct: 238 FASEMSRFVTGETLHVDGGLHL 259 >3OML-A nrPDB Length = 613 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 52/190 (27%), Positives = 90/190 (47%), Gaps = 16/190 (8%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-------------LQELEKY 49 R DG+V ++T A G+G+ AL FA GAKV+ D+ + + E+ K Sbjct: 16 RYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 50 PGIQTRVLD--VTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 G + + K I+ R+D+L N AG + +++ E+DW+ +++++ Sbjct: 76 GGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLK 135 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 + +A P M Q G II M+S S + G + Y+ K +IGL +VA + + Sbjct: 136 GSFKCTQAAFPYMKKQNYGRII-MTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 168 QGIRCNCVCP 177 + CN + P Sbjct: 195 NNVLCNVIVP 204 >4GKB-A nrPDB Length = 258 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 57/172 (33%), Positives = 86/172 (50%), Gaps = 4/172 (2%) Query: 74 RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSS 133 RLD L N AG V+ G LD + S+ N+ Y M +P + A + G I+N+SS Sbjct: 83 RLDGLVNNAG-VNDGIGLDAGRDAFVASLERNLIHYYAMAHYCVPHLKATR-GAIVNISS 140 Query: 134 VASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARG 193 ++V G N Y +K A + LT+ A + G+R N V P V TP + I Sbjct: 141 -KTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATFE 199 Query: 194 NPEEARNDFLKRQKTG-RFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWS 244 +PE + + G RF T +EIA V+L S +++ TG + +DGG++ Sbjct: 200 DPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTGEWLFVDGGYT 251 >1DOH-A nrPDB Length = 283 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 114/257 (44%), Gaps = 21/257 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L+GKV ++T A +GIG+ A+ R G KVI N ++ E E I+ D K Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAE-EVVAAIKKNGSDAACVK 85 Query: 64 Q--------IDQFANEVE---RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 + F V+ +LD++ + +G V G V D +++D +N R + + Sbjct: 86 ANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFV 145 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + + + G +I M S+ K V VYS +K A+ + +A D + I Sbjct: 146 AREAYKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITV 203 Query: 173 NCVCPGTVDTPSLQ----ERIQARGN-PEEARNDFLKRQKTG--RFATAEEIAMLCVYLA 225 N V PG + T E I N E +++ Q + R +IA + +LA Sbjct: 204 NVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLA 263 Query: 226 SDESAYVTGNPVIIDGG 242 S++ +VTG + IDGG Sbjct: 264 SNDGGWVTGKVIGIDGG 280 >1YXM-A nrPDB Length = 303 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/265 (25%), Positives = 110/265 (41%), Gaps = 32/265 (12%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY---------PGI 52 G L G+V I+T A GIG+A G+ V+ I KL+ L+ P Sbjct: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVV---IASRKLERLKSAADELQANLPPTK 70 Query: 53 QTRVLDVT------------KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDF 100 Q RV+ + K +D F +++ L N G K W Sbjct: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFG----KINFLVNNGGGQFLSPAEHISSKGWHA 126 Query: 101 SMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS 160 + N+ + M KA + + G+I+N+ + + G +A V LTKS Sbjct: 127 VLETNLTGTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKS 184 Query: 161 VAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAML 220 +A ++ GIR NCV PG + + + E + G + ++ R EE++ + Sbjct: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWG--QSFFEGSFQKIPAKRIGVPEEVSSV 242 Query: 221 CVYLASDESAYVTGNPVIIDGGWSL 245 +L S ++++TG V +DGG SL Sbjct: 243 VCFLLSPAASFITGQSVDVDGGRSL 267 >3GDF-A nrPDB Length = 267 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 67/259 (25%), Positives = 122/259 (47%), Gaps = 29/259 (11%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTRV 56 L GKV+++T A+ +G+G AA A GA V T + E ++ELEK GI+ + Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKA 77 Query: 57 LDVTKKKQIDQFAN----------EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNV 106 K Q+D + + + ++D AG +LD + W+ + +++ Sbjct: 78 Y----KCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDL 133 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVN-RCVYSTTKAAVIGLTKSVAADF 165 + KA + +G+++ +S++ + + Y+ KA I + +S+A ++ Sbjct: 134 NGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW 193 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 + R N + PG +DT L + + P+E + + GR A+E+ VY A Sbjct: 194 -RDFARVNSISPGYIDT-GLSDFV-----PKETQQLWHSMIPMGRDGLAKELKGAYVYFA 246 Query: 226 SDESAYVTGNPVIIDGGWS 244 SD S Y TG ++IDGG++ Sbjct: 247 SDASTYTTGADLLIDGGYT 265 >3V8B-A nrPDB Length = 283 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 68/256 (26%), Positives = 124/256 (48%), Gaps = 22/256 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY---PGIQTRVL--DVTKK 62 V ++T A GIG+A ALA A +G V A ++++E+ G Q L DV+ + Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 63 KQIDQFANEV----ERLDVLFNVAGFVH-HGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 Q+ ++ LD++ AG + D + +WD ++ +N+R +L + + Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTV 149 Query: 118 PKMLAQKSGNIINMSSVASS----VKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 P + + G I+ +SS+ + G + A++ + +A + + IR N Sbjct: 150 PYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIV---QQLALELGKHHIRVN 206 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARN-DFLKRQ---KTGRFATAEEIAMLCVYLASDES 229 VCPG ++T ++ + + R E A ++ K Q G+ +E++A L +L S+ + Sbjct: 207 AVCPGAIET-NISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERA 265 Query: 230 AYVTGNPVIIDGGWSL 245 +VTG+PV IDGG L Sbjct: 266 RHVTGSPVWIDGGQGL 281 >3R3S-A nrPDB Length = 294 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 74/256 (28%), Positives = 128/256 (50%), Gaps = 19/256 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKYPGIQTRV 56 GRL + ++T GIG+AAA+A+AREGA V A + + +++ L + G + + Sbjct: 45 GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVL 104 Query: 57 L-----DVTKKKQIDQFANE-VERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSM 109 L D + + + A E + LD+L VAG + D + + + +NV ++ Sbjct: 105 LPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFAL 164 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + + + +P L K +II SS+ + + + Y+ TKAA++ ++ +A ++G Sbjct: 165 FWITQEAIP--LLPKGASIITTSSI-QAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKG 221 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 IR N V PG + T +LQ + G ++ F ++ R E+A + VYLAS ES Sbjct: 222 IRVNIVAPGPIWT-ALQ---ISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQES 277 Query: 230 AYVTGNPVIIDGGWSL 245 +YVT + GG L Sbjct: 278 SYVTAEVHGVCGGEHL 293 >5IZ4-A nrPDB Length = 271 Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 119/258 (46%), Gaps = 31/258 (12%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINE------SKLQELEKYPGIQTRVLDVTK 61 V ++T +A GIG A AL FA+ G V + ++ S ++ L + G QT + D Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 62 KKQ------IDQFANEVERLDVLFNVAG---FVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 K +D A+ +R+D L N AG + H ++ +++ +N+ +Y M Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 113 IKAFLPKML----AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 +A +P + A +S +++N+SS+A + G + Y+ +K AV LT S+A + Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLA-GLNGTGSSIAYAASKGAVNTLTLSLARNLAPH 194 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG----RFATAEEIAMLCVYL 224 IR N + PG VD L + A A + L R R + EIA L +L Sbjct: 195 -IRVNALAPGMVDDGLLLRVLDA-----AAYDGVLSRMTESAPLKRVSRPAEIAELAWFL 248 Query: 225 ASDESAYVTGNPVIIDGG 242 + A +TG + + G Sbjct: 249 TAHAPA-ITGQVIAAENG 265 >4FC7-A nrPDB Length = 277 Score = 72.0 bits (175), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 70/256 (27%), Positives = 109/256 (42%), Gaps = 25/256 (9%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAK-VIATDINESKLQELEKYPGIQTR-----VL 57 L KV +T GIG A F R G VIA+ L K G R + Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 84 Query: 58 DVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFS-----MNLNVRS 108 DV + DQ E R+D+L N A G L C F+ M+++ Sbjct: 85 DVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFL-CPAGALSFNAFKTVMDIDTSG 139 Query: 109 MYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 + + + K G I+N+++ + +G + + KAAV +T+ +A ++ Q Sbjct: 140 TFNVSRVLYEKFFRDHGGVIVNITATLGN-RGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 198 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 IR N + PG + S E ++ G P+ + + + R EIA +YLAS Sbjct: 199 NIRVNSLAPGPI---SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 255 Query: 229 SAYVTGNPVIIDGG-W 243 ++YVTG ++ DGG W Sbjct: 256 ASYVTGAVLVADGGAW 271 >2NWQ-A nrPDB Length = 272 Score = 72.0 bits (175), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 11/186 (5%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT------ 60 + +T A G G+A A FA G ++ T E +LQ L +TRVL +T Sbjct: 22 STLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDR 81 Query: 61 --KKKQIDQFANEVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 +D E L L N AG + C+ DWD ++ N++ + + L Sbjct: 82 AAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLL 141 Query: 118 PKMLAQKSG-NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 P+++A +G +I+N+ SVA VY TKA V + ++ D G+R + Sbjct: 142 PRLIAHGAGASIVNLGSVAGKWP-YPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLE 200 Query: 177 PGTVDT 182 PG ++ Sbjct: 201 PGLCES 206 >1H5Q-A nrPDB Length = 265 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 73/258 (28%), Positives = 116/258 (44%), Gaps = 33/258 (12%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVI---------ATDINESKLQELEKYPGIQTRVL 57 K II+T +GIG LAF R A A D E +++ K G++T+ Sbjct: 15 KTIIVTGGNRGIG----LAFTRAVAAAGANVAVIYRSAADAVEVT-EKVGKEFGVKTKAY 69 Query: 58 --DVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV+ K I Q ++ + L AG + +D+ F ++NV ++ Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFN 129 Query: 112 MIKAFLPKML-AQKSGNIINMSSVAS------SVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 +A L Q+ G+I+ SS++S S+ G + + Y+++KAA L K +AA+ Sbjct: 130 TCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAE 189 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 + GIR N + PG V+T Q ++ R+ RFA EE+ + L Sbjct: 190 WASAGIRVNALSPGYVNTD------QTAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILL 243 Query: 225 ASDESAYVTGNPVIIDGG 242 SD + Y+TG IDGG Sbjct: 244 LSDHATYMTGGEYFIDGG 261 >5O3Z-A nrPDB Length = 263 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 62/256 (24%), Positives = 109/256 (42%), Gaps = 23/256 (8%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV---------L 57 +V ++ Q +G A+ G V D+NES L I +R + Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADT--INSRYGAGRAYGFKV 64 Query: 58 DVTKKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 D T + ++ A V+ R D+L AG + D+D S+ +N+ +L Sbjct: 65 DATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCS 124 Query: 114 KAFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + F M+ G II ++S + V G + YS K +GLT+S+A D + GI Sbjct: 125 REFSKLMIRDGIKGRIIQINSKSGKV-GSKHNSGYSAAKFGGVGLTQSLALDLAEYGITV 183 Query: 173 NCVCPGT-VDTPSLQERIQARG-----NPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 + + G + +P Q + PEE ++ + R +++ + ++ AS Sbjct: 184 HSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYAS 243 Query: 227 DESAYVTGNPVIIDGG 242 D++AY TG + + GG Sbjct: 244 DKAAYCTGQSINVTGG 259 >3ZV3-A nrPDB Length = 281 Score = 67.8 bits (164), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 73/261 (27%), Positives = 118/261 (45%), Gaps = 23/261 (8%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTK 61 +L G+V ++T A G+G+A F EGA+V D + +L+ELE + G V+ + Sbjct: 2 KLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVR 61 Query: 62 KKQIDQFANE-----VERLDVLFNVAGFVHHGTVL-DCEEKDWDFS----MNLNVRSMYL 111 Q + A E ++D L AG + T L D E D + ++NV+ Sbjct: 62 SLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYIH 121 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 +KA LP +++ + + +S+ G +Y+ TK AV+GL + +A + +R Sbjct: 122 AVKACLPALVSSRGSVVFTISNAGFYPNG--GGPLYTATKHAVVGLVRQMAFELAPH-VR 178 Query: 172 CNCVCPGTVDT-----PSLQERIQARGNPEEARNDFLKR-QKTGRFATAEEIAMLCVYLA 225 N V PG ++T SL Q+ + A D LK GR EE V+ A Sbjct: 179 VNGVAPGGMNTDLRGPSSLGLSEQSISSVPLA--DMLKSVLPIGRMPALEEYTGAYVFFA 236 Query: 226 S-DESAYVTGNPVIIDGGWSL 245 + +S TG + DGG + Sbjct: 237 TRGDSLPATGALLNYDGGMGV 257 >3U5T-A nrPDB Length = 267 Score = 66.6 bits (161), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 66/248 (26%), Positives = 113/248 (45%), Gaps = 22/248 (8%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPG----IQTRVL 57 KV I+T A++GIG A A A +G V+ ++ E +E G Q V Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQADVS 87 Query: 58 DVTKKKQIDQFANEV-ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 D +++ A E +DVL N AG + T+ + + +D + +N++ + ++ Sbjct: 88 DPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNTLREA 147 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRC--VYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 ++ + G IINMS+ S G+++ +Y+ KA V +T ++ + + I N Sbjct: 148 AQRL--RVGGRIINMST---SQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDITVNA 202 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG T E G +E R+ F K R T ++IA +LA + A+V G Sbjct: 203 VAPGPTATDLFLE-----GKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNG 257 Query: 235 NPVIIDGG 242 + +GG Sbjct: 258 QVLRANGG 265 >1BDB-A nrPDB Length = 277 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 70/260 (26%), Positives = 116/260 (44%), Gaps = 21/260 (8%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG--IQTRVLDVT 60 +L G+ +++T A G+G+A F EGAKV D + +L ELE G + V DV Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVR 61 Query: 61 KKKQIDQFAN----EVERLDVLFNVAGFVHHGTVL-DCEEKDWDFSMN----LNVRSMYL 111 + Q A+ ++D L AG + T L D E+ D + + +NV+ Sbjct: 62 SLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIH 121 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 +KA LP ++A + I +S+ G +Y+ K A++GL + +A + +R Sbjct: 122 AVKACLPALVASRGNVIFTISNAGFYPNG--GGPLYTAAKHAIVGLVRELAFELAPY-VR 178 Query: 172 CNCVCPGTVDT----PSLQERIQARGNPEEARNDFLKR-QKTGRFATAEEIAMLCVYLAS 226 N V G +++ PS + ++ D LK GR EE V+ A+ Sbjct: 179 VNGVGSGGINSDLRGPS-SLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFAT 237 Query: 227 -DESAYVTGNPVIIDGGWSL 245 ++A TG + DGG + Sbjct: 238 RGDAAPATGALLNYDGGLGV 257 >2P91-A nrPDB Length = 285 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 66/259 (25%), Positives = 117/259 (45%), Gaps = 20/259 (7%) Query: 1 MGRLDGKVIILTAAA--QGIGQAAALAFAREGAKV---IATDINESKLQELEKYPGIQTR 55 MG L+GK ++T A + I A +F REGA++ AT E +++E+ K G Sbjct: 16 MGLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLV 75 Query: 56 V-LDVTKKKQIDQFANEVER----LDVLFNVAGFV----HHGTVLDCEEKDWDFSMNLNV 106 V DV+ + I +E LD++ + + G V+D + + +M+++V Sbjct: 76 VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISV 135 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 S+ + + LP ++ ++G I+ +S + K V + V KAA+ + +A D Sbjct: 136 YSLIALTRELLP-LMEGRNGAIVTLSYYGAE-KVVPHYNVMGIAKAALESTVRYLAYDIA 193 Query: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 + G R N + G V T + E K G+ T E++ V+L S Sbjct: 194 KHGHRINAISAGPVKTLAAYSITGFHLLMEHTT----KVNPFGKPITIEDVGDTAVFLCS 249 Query: 227 DESAYVTGNPVIIDGGWSL 245 D + +TG V +D G+ + Sbjct: 250 DWARAITGEVVHVDNGYHI 268 >2X9N-A nrPDB Length = 288 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 70/275 (25%), Positives = 121/275 (44%), Gaps = 41/275 (14%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL-----QELEKYPG------ 51 ++ ++T AA+ IG+A A+ + G +V+ N ++ EL K Sbjct: 20 HMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVC 79 Query: 52 ----IQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 + VL + ++ I+ R DVL N A + ++ + +D + + Sbjct: 80 QADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQ 139 Query: 108 SMYLM----IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRC------------VYSTTK 151 L+ I FL M + N + +S++ +VN C +Y+ K Sbjct: 140 VAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLS-IVNLCDAMVDQPCMAFSLYNMGK 198 Query: 152 AAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRF 211 A++GLT+S A + GIR N V PG P A G EE ++ + ++ GR Sbjct: 199 HALVGLTQSAALELAPYGIRVNGVAPGVSLLPV------AMG--EEEKDKWRRKVPLGRR 250 Query: 212 -ATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 A+AE+IA ++L S + Y+TG+ + +DGG SL Sbjct: 251 EASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >3PXX-A nrPDB Length = 287 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 84/290 (28%), Positives = 121/290 (41%), Gaps = 54/290 (18%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI------NESKL---QELEKYPG 51 MGR+ KV+++T A+G G++ A+ A EGA +I DI NE L ++LE+ G Sbjct: 5 MGRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEE-AG 63 Query: 52 IQ---------TRVLDVTKKKQID-QFAN---EVERLDVLFNVAGFVHHGTVLD----CE 94 ++ T +DV + + + AN E +LDV+ AG G L + Sbjct: 64 LEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLPVQAFAD 123 Query: 95 EKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSV----------KGVVNR 144 D DF +N + A LP + + S II SVA + Sbjct: 124 AFDVDFVGVINT------VHAALPYLTSGAS--IITTGSVAGLIAAAQPPGAGGPQGPGG 175 Query: 145 CVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARG-NPE---EARN 200 YS K V T +AA Q IR N + P V+T L R P+ +R Sbjct: 176 AGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRA 235 Query: 201 DFL-----KRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 D L + + A +I+ +LASDES YVTG +D G L Sbjct: 236 DALLAFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >3U4C-A nrPDB Length = 281 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 63/261 (24%), Positives = 105/261 (40%), Gaps = 27/261 (10%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQTRVL 57 + + + A+QGIG+A AL A + ++ N ++ L K+P VL Sbjct: 20 HMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVL 79 Query: 58 ------DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 T+ + ++ RLDVL N T +C +D + + Sbjct: 80 AGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYID 139 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 IK M + G IIN+ G N S AA+I +K+++ I Sbjct: 140 AIKRASSLMKQNEFGRIINIVGNLWKEPGA-NMFTNSMMNAALINASKNISIQLAPHNIT 198 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKT----------GRFATAEEIAMLC 221 NC+ PG + T + ++ + + + +QK R +AEE A L Sbjct: 199 VNCLNPGFIATDRYHQFVE-----NVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALA 253 Query: 222 VYLASDESAYVTGNPVIIDGG 242 +LAS+E++Y+TG + DGG Sbjct: 254 AFLASEEASYITGQQISADGG 274 >4RGB-A nrPDB Length = 294 Score = 60.5 bits (145), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 33/216 (15%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE---------SKLQELEKYPG 51 MG LDG+V+ +T AA+G G++ A+ A +GA ++ DI E +ELE+ Sbjct: 20 MGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEE--- 76 Query: 52 IQTRVLDVTKKKQIDQFANEVER--LDVLFN--VAGFVHHGTVL--------DCEEKDWD 99 R+++ T ++ + + A+ ++ L +F+ V F H TV+ + +E+D Sbjct: 77 -TARLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDAS 135 Query: 100 FSMNLNVRSMYLMI----KAFLPKMLAQ-KSGNIINMSSVASSVKGVVNRC---VYSTTK 151 ++ L + M + + + +P M + + GN+I SS+ + + R Y T+K Sbjct: 136 EALRLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSK 195 Query: 152 AAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQE 187 A+ GL +S A IR N V P TP + E Sbjct: 196 LAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITE 231 >2O23-A nrPDB Length = 265 Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 66/258 (25%), Positives = 109/258 (42%), Gaps = 30/258 (11%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT--RVLDVTK 61 + G V ++T A G+G A A +GA + D+ S + K G DVT Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 69 Query: 62 KKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEE------KDWDFSMNLNVRSMYL 111 +K + + R+DV N AG + ++ +D+ +++N+ + Sbjct: 70 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 129 Query: 112 MIKAFLPKM------LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 +I+ +M + G IIN +SVA+ +G V + YS +K ++G+T +A D Sbjct: 130 VIRLVAGEMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPIARDL 188 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK--TGRFATAEEIAMLCVY 223 GIR + PG TP L PE+ N FL Q R E A L Sbjct: 189 APIGIRVMTIAPGLFGTPLLTSL------PEKVCN-FLASQVPFPSRLGDPAEYAHLVQA 241 Query: 224 LASDESAYVTGNPVIIDG 241 + E+ ++ G + +DG Sbjct: 242 II--ENPFLNGEVIRLDG 257 >1W73-A nrPDB Length = 302 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 37/122 (30%), Positives = 66/122 (54%), Gaps = 6/122 (4%) Query: 122 AQKSGNIINMSSV-ASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 AQK ++++++ A + G V ++ KA V ++KS+AA++ + G+R N + PG + Sbjct: 153 AQKGAAFLSITTIYAETGSGFV--VPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPI 210 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 T R+ G E+ + + R GR T EE+A L +L SD ++++ G + D Sbjct: 211 KTKGAFSRLDPTGTFEK---EMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFD 267 Query: 241 GG 242 GG Sbjct: 268 GG 269 >1P33-A nrPDB Length = 289 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 47/152 (30%), Positives = 79/152 (51%), Gaps = 24/152 (15%) Query: 105 NVRSMYLMIKAFLPKML---AQKSG---NIINMSSVASSVKGVVNRCVYSTTKAAVIGLT 158 N + Y +IKAF ++ A++ G +I+NM +S + ++ +Y+ K A+ GLT Sbjct: 148 NAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTS-QPLLGYTMYTMAKEALEGLT 206 Query: 159 KSVAADFIQQGIRCNCVCPGTVDTP-----SLQERIQARGNPEEARNDFLKRQKTGRFAT 213 +S A + IR N V PG P S+QE + R P RN ++ Sbjct: 207 RSAALELASLQIRVNGVSPGLSVLPDDMPFSVQEDYR-RKVPLYQRN-----------SS 254 Query: 214 AEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 AEE++ + ++L S ++ Y+TG + +DGG+SL Sbjct: 255 AEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >1E3W-A nrPDB Length = 261 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/259 (26%), Positives = 112/259 (43%), Gaps = 32/259 (12%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT--RVLDVTK 61 + G V ++T A G+G + A +GA + D+ S+ + K G +VT Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 Query: 62 KKQID---QFANE-VERLDVLFNVAGFV------HHGTVLDCEEKDWDFSMNLNVRSMYL 111 +K++ A E R+DV N AG H +D+ +N+N+ + Sbjct: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 Query: 112 MIKAFLPKMLAQ-------KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 +I+ + ++ Q + G IIN +SVA+ +G V + YS +K ++G+T +A D Sbjct: 128 VIR-LVAGVMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPIARD 185 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK--TGRFATAEEIAMLCV 222 GIR + PG TP L P+ RN FL Q R E A L Sbjct: 186 LAPIGIRVVTIAPGLFATPLLTTL------PDTVRN-FLASQVPFPSRLGDPAEYAHLVQ 238 Query: 223 YLASDESAYVTGNPVIIDG 241 + E+ ++ G + +DG Sbjct: 239 MVI--ENPFLNGEVIRLDG 255 >1FJH-A nrPDB Length = 257 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 61/263 (23%), Positives = 108/263 (41%), Gaps = 46/263 (17%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESK-LQELEKYPGIQTRVLDVTKKKQID 66 +I+++ A GIG A G +++ DI +++ + +L G + + DV K Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAEVIADLSTAEGRKQAIADVLAKCS-- 60 Query: 67 QFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSG 126 + +D L AG L + K +++N ++ AFLP + Sbjct: 61 ------KGMDGLVLCAG-------LGPQTKVLGNVVSVNYFGATELMDAFLPALKKGHQP 107 Query: 127 NIINMSSVASS--------------------VKGVVNRC-------VYSTTKAAVIGLTK 159 + +SSVAS+ + +V Y+ +K A+ + Sbjct: 108 AAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVR 167 Query: 160 SVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAM 219 AA + + G+R N + PG +TP LQ +Q +P + GR A E+A Sbjct: 168 KRAAAWGEAGVRLNTIAPGATETPLLQAGLQ---DPRYGESIAKFVPPMGRRAEPSEMAS 224 Query: 220 LCVYLASDESAYVTGNPVIIDGG 242 + +L S ++YV G ++IDGG Sbjct: 225 VIAFLMSPAASYVHGAQIVIDGG 247 >3E9N-A nrPDB Length = 245 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 8/194 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKK- 62 L K+ ++T A G+G +R+ V A N L L + G++ D+ K+ Sbjct: 3 LKKKIAVVTGATGGMGIEIVKDLSRDHI-VYALGRNPEHLAALAEIEGVEPIESDIVKEV 61 Query: 63 ---KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 +D+ N ++ +D L + A T+ +W ++LNV + + LP Sbjct: 62 LEEGGVDKLKN-LDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLPA 120 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 + A SG +I ++S A + N +Y+ +K A+ GL + + GIR + V PG Sbjct: 121 LRAA-SGCVIYINSGAGNGPHPGN-TIYAASKHALRGLADAFRKEEANNGIRVSTVSPGP 178 Query: 180 VDTPSLQERIQARG 193 +TP LQ + ++G Sbjct: 179 TNTPMLQGLMDSQG 192 >3PPI-A nrPDB Length = 281 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 69/258 (26%), Positives = 114/258 (44%), Gaps = 29/258 (11%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVT 60 + +G I++ A G+G+A +G V+ D+ K + L G + + +VT Sbjct: 27 QFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVT 86 Query: 61 KKKQI---DQFANEVERLDVL------FNVAGFV--HHGTVLDCE--EKDWDFSMN--LN 105 + + + AN++ RL F VA + G+ D K D +N N Sbjct: 87 SEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNGTYN 146 Query: 106 V-RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 V R + I A P+ ++ G ++ +S+A +G + + Y+ KA VIGLT + A D Sbjct: 147 VARLVAASIAAAEPRENGER-GALVLTASIAG-YEGQIGQTAYAAAKAGVIGLTIAAARD 204 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK-TGRFATAEEIAMLCVY 223 GIR N + PGT+ TP + E + EEA F R T +E A + Sbjct: 205 LSSAGIRVNTIAPGTMKTP-IMESVG-----EEALAKFAANIPFPKRLGTPDEFADAAAF 258 Query: 224 LASDESAYVTGNPVIIDG 241 L ++ Y+ G + +DG Sbjct: 259 LLTN--GYINGEVMRLDG 274 >2YW9-A nrPDB Length = 261 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 19/198 (9%) Query: 58 DVTKKKQIDQFANEVER----LDVLFNVAGFV----HHGTVLDCEEKDWDFSMNLNVRSM 109 DVT+ +++D V+ LD L + F G +D +DW ++ ++ S+ Sbjct: 66 DVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYSL 125 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + + P L ++ G I+ ++ AS K V V + KAA+ + +A + +G Sbjct: 126 VAVARRAEP--LLREGGGIVTLTYYASE-KVVPKYNVMAIAKAALEASVRYLAYELGPKG 182 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNP--EEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 +R N + G V T + AR P + + + R T EE+ L ++L S Sbjct: 183 VRVNAISAGPVRT------VAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSP 236 Query: 228 ESAYVTGNPVIIDGGWSL 245 ++ +TG V +D G+ + Sbjct: 237 LASGITGEVVYVDAGYHI 254 >3OIG-A nrPDB Length = 266 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 63/260 (24%), Positives = 117/260 (45%), Gaps = 27/260 (10%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR----VL 57 L+G+ I++ A + I A + GA++I T E + + + G R +L Sbjct: 5 LEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIIL 64 Query: 58 --DVTKKKQIDQ-FANEVERLDVLFNVA---GFVHH----GTVLDCEEKDWDFSMNLNVR 107 DVT +I+ FA+ E++ V+ +A F + G L+ + + N++ Sbjct: 65 PCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSY 124 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 S+ ++KA P M + G+I+ ++ + + + N V KA++ K +AAD + Sbjct: 125 SLTAVVKAARPMM--TEGGSIVTLTYLGGELV-MPNYNVMGVAKASLDASVKYLAADLGK 181 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARG--NPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 + IR N + G + T + A+G + D +R R T EE+ +L Sbjct: 182 ENIRVNSISAGPIRT------LSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLF 235 Query: 226 SDESAYVTGNPVIIDGGWSL 245 SD S +TG + +D G+ + Sbjct: 236 SDMSRGITGENLHVDSGFHI 255 >6CGE-A nrPDB Length = 328 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 17/203 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGA---KVIAT--DI-NESKLQE----LEKYPG-IQTRV 56 V+++T + GIG A+ A + + KV AT D+ + +L E L PG ++T Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 57 LDVTKKKQIDQFANEVE--RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 LDV K + V R+DVL AG G + E +++NV M++ Sbjct: 65 LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 AFLP M + SG ++ SV + G+ VY +K A+ GL +S+A + G+ + Sbjct: 125 AFLPDMKRRGSGRVLVTGSVG-GLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Query: 175 VCPGTVDTPSLQERIQARGNPEE 197 + G V T +++ + G+PEE Sbjct: 184 IECGPVHTAFMEKVL---GSPEE 203 >1A27-A nrPDB Length = 289 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 17/203 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGA---KVIAT--DI-NESKLQE----LEKYPG-IQTRV 56 V+++T + GIG A+ A + + KV AT D+ + +L E L PG ++T Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 57 LDVTKKKQIDQFANEVE--RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 LDV K + V R+DVL AG G + E +++NV M++ Sbjct: 64 LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 123 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 AFLP M + SG ++ SV + G+ VY +K A+ GL +S+A + G+ + Sbjct: 124 AFLPDMKRRGSGRVLVTGSVG-GLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 182 Query: 175 VCPGTVDTPSLQERIQARGNPEE 197 + G V T +++ + G+PEE Sbjct: 183 IECGPVHTAFMEKVL---GSPEE 202 >5KOI-A nrPDB Length = 293 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 51/199 (25%), Positives = 87/199 (43%), Gaps = 20/199 (10%) Query: 58 DVTKKKQIDQFANEVER----LDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVRSM 109 DV +D E+E+ LD L + GF G D ++ +FS + + + Sbjct: 86 DVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRE-NFSRTMVISAY 144 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 A + L + G+I+ ++ S + + N V KAA+ + + +AAD+ QG Sbjct: 145 SFTEVAQRAEKLMKDGGSILTLT-YGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQG 203 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG---RFATAEEIAMLCVYLAS 226 IR N + G V R A +AR F +++ R +++ VYL S Sbjct: 204 IRVNAISAGPV-------RTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLS 256 Query: 227 DESAYVTGNPVIIDGGWSL 245 D S+ VTG +D G+++ Sbjct: 257 DLSSGVTGEIHFVDSGYNI 275 >4M89-A nrPDB Length = 261 Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 67/262 (25%), Positives = 116/262 (44%), Gaps = 25/262 (9%) Query: 1 MGRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL- 57 MG L GK I++T + + I A A +GA++ T + + + + K L Sbjct: 1 MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELV 60 Query: 58 ---DVTKKKQIDQ-FAN---EVERLDVLFNVAGFVHH----GTVLDCEEKD-WDFSMNLN 105 DV +I+Q FA+ + LD L + GF G LD ++ ++ + ++ Sbjct: 61 FRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEIS 120 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S+ + KA P M + S I+ +S + + V+ + N V KA++ + AA Sbjct: 121 AYSLPALAKAARPMMRGRNSA-IVALSYLGA-VRAIPNYNVMGMAKASLEAGIRFTAACL 178 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEAR--NDFLKRQKTGRFATAEEIAMLCVY 223 ++GIRCN + G + T + A G + + R T EE+ + Sbjct: 179 GKEGIRCNGISAGPIKT------LAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAF 232 Query: 224 LASDESAYVTGNPVIIDGGWSL 245 L SD S+ +TG +DGG+S+ Sbjct: 233 LLSDLSSGITGEITYVDGGYSI 254 >5TF4-A nrPDB Length = 274 Score = 53.5 bits (127), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 108/250 (43%), Gaps = 40/250 (16%) Query: 12 TAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-EKYPGIQTRVLDVTKKKQIDQFAN 70 TA++ G A LAF +G + + +++ L E+ G DV+ ID N Sbjct: 33 TASSAG----AELAFTYQGEAM------KKRVEPLAEEVKGFVCGHCDVSDSASIDAVFN 82 Query: 71 EVER----LDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 +E+ LD L + GF G +D E ++ +MN++V S+ + K + L Sbjct: 83 TIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSLTALTKR--AEKLM 140 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 G+I+ ++ + K V N V KAA+ K +A D + IR N + G + T Sbjct: 141 SDGGSILTLTYYGAE-KVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAISAGPIKT 199 Query: 183 PSLQERIQARGNPEEARNDF---LKRQKTG----RFATAEEIAMLCVYLASDESAYVTGN 235 + A G DF LK + R T EE+ +YL SD S VTG Sbjct: 200 ------LAASG-----IGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSVTGE 248 Query: 236 PVIIDGGWSL 245 +D G+++ Sbjct: 249 VHHVDSGYNI 258 >4DA9-A nrPDB Length = 280 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 64/253 (25%), Positives = 111/253 (43%), Gaps = 21/253 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESK--LQELEKYPGIQTRVLDV------ 59 V I+T +GIG A A A G + T I +++ + + G+ RV+ + Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 60 --TKKKQIDQFANEVERLDVLFNVAGF--VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + +D E R+D L N AG + LD + +++D + +N+R +A Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQA 150 Query: 116 FLPKMLA---QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 L MLA + S +IIN++SV S+V R Y +KA + ++ +A + GI Sbjct: 151 VLKAMLASDARASRSIINITSV-SAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAV 209 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 V PG + + G + L + R+ E+I + LA + + Sbjct: 210 FEVRPGIIRS---DMTAAVSGKYDGLIESGLVPMR--RWGEPEDIGNIVAGLAGGQFGFA 264 Query: 233 TGNPVIIDGGWSL 245 TG+ + DGG S+ Sbjct: 265 TGSVIQADGGLSI 277 >3UCF-A nrPDB Length = 223 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 49/191 (25%), Positives = 84/191 (43%), Gaps = 18/191 (9%) Query: 57 LDVTKKKQIDQFANEVERLDVLFNVAG-FVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 LD++ +K + + + D L AG + G V+D E ++ + L K Sbjct: 42 LDISDEKSVYHYFETIGAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKH 101 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + K G I ++S S K V N V + AA+ TK +A + IR N + Sbjct: 102 GARYL---KQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAI 156 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKT----GRFATAEEIAMLCVYLASDESAY 231 PG T + +G + R+ +R ++ G+ A +IAM YL + +++Y Sbjct: 157 SPGLTKTEAY------KGMNADDRDAMYQRTQSHLPVGKVGEASDIAM--AYLFAIQNSY 208 Query: 232 VTGNPVIIDGG 242 +TG + +DGG Sbjct: 209 MTGTVIDVDGG 219 >5ILO-A nrPDB Length = 271 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 53/192 (27%), Positives = 88/192 (45%), Gaps = 24/192 (12%) Query: 6 GKVIILTAAAQGIG-QAAALAFAREGAKVIATDINES-----KLQELEKYPGIQTRVLDV 59 GK ++T A GIG Q + A AKV D+ ++ KL+ + +DV Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDV 74 Query: 60 TKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 KK ++ E+ + +D++ NVAG + +KD ++ +N+ + + Sbjct: 75 ANKKGVEATYEEIAKTFGNIDIVVNVAGIFN--------DKDVQRTLLVNLGGIINSTLS 126 Query: 116 FLPKMLAQ---KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQGI 170 LP M K G ++NMSSV + + VY TKA +I T+ +A + + + GI Sbjct: 127 ALPYMGKDNGGKGGIVVNMSSVV-GLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGI 185 Query: 171 RCNCVCPGTVDT 182 + VCPG T Sbjct: 186 KFVTVCPGATMT 197 >5TQV-A nrPDB Length = 233 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/182 (26%), Positives = 83/182 (45%), Gaps = 10/182 (5%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 K +++ A++G+G+ + R+G VIAT +++ L L G LD+T+ +QI Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL-GAHAHALDITQPEQIA 68 Query: 67 QFANEV--ERLDVLFNVAGFVHHGT--VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 ++ ERLDV V+G T V D+D M+ NVR ++ LP ++ Sbjct: 69 ALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLP-LVE 127 Query: 123 QKSGNIINMSSVASSVKGVVNRC--VYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 G + +SS S+ +Y +KAA+ + + A + C + PG V Sbjct: 128 DARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLR--IASLQTRHAACISLHPGWV 185 Query: 181 DT 182 T Sbjct: 186 RT 187 >5YCX-A nrPDB Length = 266 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 63/261 (24%), Positives = 112/261 (42%), Gaps = 23/261 (8%) Query: 1 MGRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINES---KLQEL-EKYPGIQT 54 M L GK ++ A + I A + GAK+I T E ++EL + G ++ Sbjct: 3 MELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQES 62 Query: 55 RVL--DVTKKKQI----DQFANEVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNL 104 VL DVT +++ + EV + + + F + G +D + + N+ Sbjct: 63 LVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNI 122 Query: 105 NVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 + S+ + + K + + GNI+ ++ + + V N V KA++ K +A D Sbjct: 123 SAFSLTAVARE--AKKVMTEGGNILTLTYLGGE-RVVKNYNVMGVAKASLEASVKYLAND 179 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 Q GIR N + G + T S + G+ + +R R T EE+ V+L Sbjct: 180 LGQHGIRVNAISAGPIRTLS----AKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFL 235 Query: 225 ASDESAYVTGNPVIIDGGWSL 245 SD + VTG + +D G+ + Sbjct: 236 FSDLARGVTGENIHVDSGYHI 256 >2QHX-A nrPDB Length = 328 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 16/148 (10%) Query: 105 NVRSMYLMIKAFLPKML---AQKSG---NIINMSSVASSVKGVVNRCVYSTTKAAVIGLT 158 N + Y +IKAF ++ A+ G +IINM A + + ++ +Y+ K A+ GLT Sbjct: 187 NAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVD-AMTNQPLLGYTIYTMAKGALEGLT 245 Query: 159 KSVAADFIQQGIRCNCVCPG-TVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEI 217 +S A + IR N V PG +V + + E R+ Q R ++A E+ Sbjct: 246 RSAALELAPLQIRVNGVGPGLSVLVDDMPPAVW-----EGHRSKVPLYQ---RDSSAAEV 297 Query: 218 AMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + ++L S ++ Y+TG V +DGG+SL Sbjct: 298 SDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2BFA-A nrPDB Length = 288 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 16/148 (10%) Query: 105 NVRSMYLMIKAFLPKML---AQKSG---NIINMSSVASSVKGVVNRCVYSTTKAAVIGLT 158 N + Y +IKAF ++ A+ G +IINM A + + ++ +Y+ K A+ GLT Sbjct: 147 NAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVD-AMTNQPLLGYTIYTMAKGALEGLT 205 Query: 159 KSVAADFIQQGIRCNCVCPG-TVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEI 217 +S A + IR N V PG +V + + E R+ Q R ++A E+ Sbjct: 206 RSAALELAPLQIRVNGVGPGLSVLVDDMPPAVW-----EGHRSKVPLYQ---RDSSAAEV 257 Query: 218 AMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + ++L S ++ Y+TG V +DGG+SL Sbjct: 258 SDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >1SNY-A nrPDB Length = 267 Score = 50.1 bits (118), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 27/201 (13%) Query: 9 IILTAAAQGIGQA---AALAFAREGAKVIATDINESKLQELE----KYPGIQTRVLDVTK 61 I++T +G+G A L + + T N + +ELE + I +D+ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRN 83 Query: 62 KKQIDQFANEVER------LDVLFNVAGFVHHGT-VLDCEEKDWDFSMNLNVRSMYLMIK 114 D+ ++E L+VLFN AG + ++ ++ N ++ K Sbjct: 84 FDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAK 143 Query: 115 AFLPKMLAQKSGN-----------IINMSSVASSVKGVVNRCVYS--TTKAAVIGLTKSV 161 A LP + N IINMSS+ S++G + +Y+ T+K+A+ TKS+ Sbjct: 144 ACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSL 203 Query: 162 AADFIQQGIRCNCVCPGTVDT 182 + D Q I C + PG V T Sbjct: 204 SVDLYPQRIMCVSLHPGWVKT 224 >2DKN-A nrPDB Length = 255 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 3/96 (3%) Query: 147 YSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQ 206 Y+ +K AV L + D+ +G+R N V PG V+TP LQ ++ +P + Sbjct: 153 YAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQ---ASKADPRYGESTRRFVA 209 Query: 207 KTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 GR + E+A +L +++++ G+ + +DGG Sbjct: 210 PLGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGG 245 >3DWF-A nrPDB Length = 276 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 54/198 (27%), Positives = 95/198 (47%), Gaps = 28/198 (14%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL---------EKYPGIQT 54 L GK +I+T A++GIG+ A A+ GA V+ T ++ LQ++ I Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 55 RVLDVTKKKQ-IDQFANEVERLD------VLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 + D+T ++ + + N + LD VL+N F HG + + + SM +N Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFF-HGEIDNVRK-----SMEVNFH 122 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 S ++ A +P ML Q G+I +SSVA + + YS +K A+ G ++ ++F+ Sbjct: 123 SFVVLSVAAMP-MLMQSQGSIAVVSSVAGKITYPL-IAPYSASKFALDGFFSTLRSEFLV 180 Query: 168 QGIRCN---CVCPGTVDT 182 + + C+ G +DT Sbjct: 181 NKVNVSITLCIL-GLIDT 197 >3U9L-A nrPDB Length = 324 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 54/186 (29%), Positives = 85/186 (45%), Gaps = 14/186 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIAT--DINESKLQELEKYPG--------IQTRV 56 K+I++T A+ G G+ A A A G +V A+ DI +E G ++T Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLE 65 Query: 57 LDVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 LDV + + IDQ E R+DVL + AG + G + + ++NV S + Sbjct: 66 LDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVLSTQRV 125 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 +A LP M QK G +I +SS +S+ Y KAA+ + A + + GI Sbjct: 126 NRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRWGIET 185 Query: 173 NCVCPG 178 + + PG Sbjct: 186 SIIVPG 191 >4JQC-A nrPDB Length = 282 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 36/267 (13%) Query: 1 MGRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINESKLQELEKYPG-IQTRVL 57 MG L GK I++T A I A A REGA++ T N+ +E++ + + ++ Sbjct: 21 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 80 Query: 58 ---DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD---------FSMNLN 105 DV + ID E+ ++ F+ GFVH ++ D D F + + Sbjct: 81 LQCDVAEDASIDTMFAELGKVWPKFD--GFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 138 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 + S + A + + ++ +S + + + + N V KA++ + +A Sbjct: 139 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAE-RAIPNYNVMGLAKASLEANVRYMANAM 197 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKR-------QKTGRFATAEEIA 218 +G+R N + G + T + A G DF K R T E++ Sbjct: 198 GPEGVRVNAISAGPIRT------LAASG-----IKDFRKMLAHCEAVTPIRRTVTIEDVG 246 Query: 219 MLCVYLASDESAYVTGNPVIIDGGWSL 245 +L SD SA ++G V +DGG+S+ Sbjct: 247 NSAAFLCSDLSAGISGEVVHVDGGFSI 273 >5CFZ-A nrPDB Length = 305 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 36/267 (13%) Query: 1 MGRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINESKLQELEKYPG-IQTRVL 57 MG L GK I++T A I A A REGA++ T N+ +E++ + + ++ Sbjct: 44 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 103 Query: 58 ---DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD---------FSMNLN 105 DV + ID E+ ++ F+ GFVH ++ D D F + + Sbjct: 104 LQCDVAEDASIDTMFAELGKVWPKFD--GFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 161 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 + S + A + + ++ +S + + + + N V KA++ + +A Sbjct: 162 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAE-RAIPNYNVMGLAKASLEANVRYMANAM 220 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKR-------QKTGRFATAEEIA 218 +G+R N + G + T + A G DF K R T E++ Sbjct: 221 GPEGVRVNAISAGPIRT------LAASG-----IKDFRKMLAHCEAVTPIRRTVTIEDVG 269 Query: 219 MLCVYLASDESAYVTGNPVIIDGGWSL 245 +L SD SA ++G V +DGG+S+ Sbjct: 270 NSAAFLCSDLSAGISGEVVHVDGGFSI 296 >4ALL-A nrPDB Length = 277 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 59/248 (23%), Positives = 98/248 (39%), Gaps = 17/248 (6%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY------PGIQTRVLDVTK 61 VI+ A + I A + GAK++ T E +ELEK P +DV Sbjct: 31 VIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQS 90 Query: 62 KKQI----DQFANEVERLDVLFNVAGFVHHGTVLD--CEEKDWDFSMNLNVRSMYLMIKA 115 +++ +Q +V +D +++ F + + E F + ++ S L I A Sbjct: 91 DEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVA 150 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 K L + G+I+ + + V N V KA++ K +A D IR N + Sbjct: 151 HEAKKLMPEGGSIVATTYLGGEF-AVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAI 209 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 G + T S + G + +R R E+ YL SD S+ VTG Sbjct: 210 SAGPIRTLS----AKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGE 265 Query: 236 PVIIDGGW 243 + +D G+ Sbjct: 266 NIHVDSGF 273 >5I9N-A nrPDB Length = 276 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 118/261 (45%), Gaps = 26/261 (9%) Query: 1 MGRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINE---SKLQELEKYPGIQTR 55 MG LDGK I+LT + + I A A REGA++ T + + ++ E G + Sbjct: 1 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELV 60 Query: 56 V-LDVTKKKQIDQ-FAN---EVERLDVLFNVAGFVHH----GTVLD-CEEKDWDFSMNLN 105 DV QID FA+ + LD L + GF G LD +++ + +++ Sbjct: 61 FPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDIS 120 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S + KA LP ML+ + +++ +S + + + + N KAA+ + +A Sbjct: 121 AYSFPALAKAALP-MLSDDA-SLLTLSYLGAE-RAIPNYNTMGLAKAALEASVRYLAVSL 177 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEE--ARNDFLKRQKTGRFATAEEIAMLCVY 223 +G+R N + G + T + I++ G + N LKR T E++ + Sbjct: 178 GAKGVRVNAISAGPIKTLA-ASGIKSFGKILDFVESNSPLKRN-----VTIEQVGNAGAF 231 Query: 224 LASDESAYVTGNPVIIDGGWS 244 L SD ++ VT + +D G++ Sbjct: 232 LLSDLASGVTAEVMHVDSGFN 252 >4NR0-A nrPDB Length = 273 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 62/268 (23%), Positives = 117/268 (43%), Gaps = 37/268 (13%) Query: 1 MGRLDGK--VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY-PGIQTRV- 56 MG L GK +I+ A+ I A A REGA++ T N+ +E++ G +R Sbjct: 1 MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPE 60 Query: 57 ----LDVTKKKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCE------EKDWDFSM 102 DV QI+ + LD++ + GF G LD + + + + Sbjct: 61 LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAP-GDQLDGDFTAVTTREGFRIAH 119 Query: 103 NLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA 162 +++ S + KA +M+ ++G+++ +S + + + + N V KA++ + +A Sbjct: 120 DISAYSFIALAKAG-REMMKGRNGSLLTLSYLGAE-RTMPNYNVMGMAKASLEAGVRYLA 177 Query: 163 ADFIQQGIRCNCVCPGTVDT------PSLQERIQARGNPEEARNDFLKRQKTGRFATAEE 216 +G R N V G + T S ++ + A R L+R T EE Sbjct: 178 GSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAA-----NERQTPLRRN-----VTIEE 227 Query: 217 IAMLCVYLASDESAYVTGNPVIIDGGWS 244 + +L SD ++ ++G + +DGG++ Sbjct: 228 VGNAGAFLCSDLASGISGEILYVDGGFN 255 >4DRY-A nrPDB Length = 281 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 103/249 (41%), Gaps = 43/249 (17%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIAT----DINESKLQELEKYPG--IQTR 55 G +G++ ++T G+G+ A A + EG V+ T D+ ++ E+ G ++ Sbjct: 29 GSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAV 88 Query: 56 VLDVTKKKQIDQ-FAN---EVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMY 110 V DV Q+ FA E RLD+L N AG V + + + W+ + N+ + Sbjct: 89 VCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAF 148 Query: 111 LMIKAFLPKMLAQ--KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 L + M AQ + G IIN S+++ N Y+ TK A+ GLTKS A D Sbjct: 149 LCTQHAFRMMKAQTPRGGRIINNGSISAQTP-RPNSAPYTATKHAITGLTKSTALDGRMH 207 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFAT-----------AEEI 217 I C G +D GN A D R TG E I Sbjct: 208 DIAC-----GQIDI----------GN---AATDMTARMSTGVLQANGEVAAEPTIPIEHI 249 Query: 218 AMLCVYLAS 226 A VY+AS Sbjct: 250 AEAVVYMAS 258 >1B15-A nrPDB Length = 254 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 52/192 (27%), Positives = 81/192 (42%), Gaps = 19/192 (9%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAK--VIATDI-NESKLQELEKYP---GIQTRVL 57 L K +I AA GIG + + K VI + N + L EL+ I Sbjct: 3 LTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHTY 62 Query: 58 DVT-----KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLN-VRSMYL 111 DVT KK + + ++++ +D+L N AG +LD + + ++N + + Sbjct: 63 DVTVPVAESKKLLKKIFDQLKTVDILINGAG------ILDDHQIERTIAINFTGLVNTTT 116 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 I F K G I N+ SV + + VYS +KAAV+ T S+A G+ Sbjct: 117 AILDFWDKRKGGPGGIIANICSV-TGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGVT 175 Query: 172 CNCVCPGTVDTP 183 + PG TP Sbjct: 176 AYSINPGITRTP 187 >3K2E-A nrPDB Length = 296 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 66/264 (25%), Positives = 113/264 (42%), Gaps = 37/264 (14%) Query: 4 LDGK--VIILTAAAQGIGQAAALAFAREGAKVIATDINES---KLQELEKYPGIQTRV-L 57 ++GK VII A + + A A +GA+V T ++E+ ++ L + G++ V Sbjct: 28 MEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVKLTVPC 87 Query: 58 DVTKKKQIDQ----FANEVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVRSM 109 DV+ + +D A E LD + + F G +D ++ SM+++ S Sbjct: 88 DVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCYSF 147 Query: 110 -YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 Y+ KA + L G+I+ +S + K V + V KAA+ K +A D +Q Sbjct: 148 TYIASKA---EPLMTNGGSILTLSYYGAE-KVVPHYNVMGVCKAALEASVKYLAVDLGKQ 203 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPE-------EARNDFLKRQKTGRFATAEEIAMLC 221 IR N + G V T + + G + N L+R T +++ Sbjct: 204 QIRVNAISAGPVRT------LASSGISDFHYILTWNKYNSPLRRN-----TTLDDVGGAA 252 Query: 222 VYLASDESAYVTGNPVIIDGGWSL 245 +YL SD TG V +D G+ + Sbjct: 253 LYLLSDLGRGTTGETVHVDCGYHV 276 >3KZV-A nrPDB Length = 254 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 55/210 (26%), Positives = 104/210 (49%), Gaps = 18/210 (8%) Query: 6 GKVIILTAAAQGIGQAAA-LAFAREGAKVI-ATDINESKLQEL-EKYPGIQTRVL-DVTK 61 GKVI++T ++GIG++ + F+ + V+ +E+ L++L EKY V+ D+T+ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKD---WDFSMNLNVRSMYLMIK 114 + Q N ++D L AG + V + E D W ++N S+ ++ Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLE--PVQNVNEIDVNAWKKLYDINFFSIVSLVG 119 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 LP+ L + +GN++ +SS A ++ + Y ++KAA+ ++A + ++ ++ Sbjct: 120 IALPE-LKKTNGNVVFVSSDACNMY-FSSWGAYGSSKAALNHFAMTLANE--ERQVKAIA 175 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLK 204 V PG VDT +Q I+ P + LK Sbjct: 176 VAPGIVDT-DMQVNIRENVGPSSMSAEQLK 204 >2PD3-A nrPDB Length = 275 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 63/266 (23%), Positives = 116/266 (43%), Gaps = 35/266 (13%) Query: 1 MGRLDGK--VIILTAAAQGIGQAAALAFAREGAKVIATDINESK-------LQELEKYPG 51 MG L GK +I+ A + I A + +GA + T +NES QEL P Sbjct: 1 MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNS-PY 59 Query: 52 IQTRVLDVTKKKQIDQFANEVER----LDVLFNVAGFVH----HGTVLDCEEKDWDFSMN 103 + LDV+K++ N V++ LD + + F G++L+ + ++ +M Sbjct: 60 VYE--LDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAME 117 Query: 104 LNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163 ++V S+ + P L +++ +S + S+ K + + V KAA+ + +A Sbjct: 118 ISVYSLIELTNTLKP--LLNNGASVLTLSYLGST-KYMAHYNVMGLAKAALESAVRYLAV 174 Query: 164 DFIQQGIRCNCVCPGTVDTPSLQE----RIQARGNPEEARNDFLKRQKTGRFATAEEIAM 219 D + IR N + G + T + R+ + N A L++ + EE+ Sbjct: 175 DLGKHHIRVNALSAGPIRTLASSGIADFRMILKWNEINAP---LRKN-----VSLEEVGN 226 Query: 220 LCVYLASDESAYVTGNPVIIDGGWSL 245 +YL S S+ V+G +D G+ + Sbjct: 227 AGMYLLSSLSSGVSGEVHFVDAGYHV 252 >4HBG-A nrPDB Length = 286 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 26/182 (14%) Query: 22 AALAFAREGAKVIATDINE-SKLQELEKYPGIQTRVLDVTKKKQ--------IDQFANEV 72 + L++ R+ A IA D + + E Y GI+ D KQ ++++N Sbjct: 53 SGLSYQRQCA--IAIDFKKWPHWLDYESYDGIEY-FKDRPPLKQKYSTLFDPCNKWSNNE 109 Query: 73 ER--LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM----IKAFL------PKM 120 R +++L N AG + MN+N S M IK + P++ Sbjct: 110 RRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 Query: 121 LAQKS-GNIINMSSVASSVK-GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPG 178 Q + I+N+SS+ S K V VYS +KAA+ T+ +AA+ + IRC + PG Sbjct: 170 SGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 Query: 179 TV 180 V Sbjct: 230 LV 231 >4ZJU-A nrPDB Length = 275 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 107/264 (40%), Gaps = 33/264 (12%) Query: 2 GRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINES---KLQEL-EKYPGIQTR 55 G L GK ++ A I A A REGA++ T NE ++ E E++ Sbjct: 12 GLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVF 71 Query: 56 VLDVTKKKQIDQ-FANEVERLDVLFNVAGFVHH----------GTVLDCEEKD-WDFSMN 103 DV +ID FA + D V G VH G D ++D + + + Sbjct: 72 PCDVAVDAEIDNAFAELAKHWD---GVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHD 128 Query: 104 LNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163 ++ S M +A P +L + G ++ ++ S + + N V KA++ + +A+ Sbjct: 129 ISAYSFVAMARAAKP-LLQARQGCLLTLTYQGSE-RVMPNYNVMGMAKASLEAGVRYLAS 186 Query: 164 DFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG---RFATAEEIAML 220 GIR N + G + R A + R +K R T EE+ Sbjct: 187 SLGVDGIRVNAISAGPI-------RTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNA 239 Query: 221 CVYLASDESAYVTGNPVIIDGGWS 244 ++L S ++ +TG + +D G++ Sbjct: 240 ALFLCSPWASGITGEILYVDAGFN 263 >5PGZ-A nrPDB Length = 276 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 58/219 (26%), Positives = 99/219 (45%), Gaps = 36/219 (16%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL---------EKYPGIQT 54 L GK +I+T A++GIG+ A ++ GA V+ T +E LQ++ I Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 55 RVLDVTKKKQ-IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFS-----MNLNVRS 108 + D+T +Q I + + LD+L ++H T D M +N S Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDML-----ILNHITQTSLSLFHDDIHSVRRVMEVNFLS 130 Query: 109 MYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCV---YSTTKAAVIGLTKSVAADF 165 +M A LP ML Q +G+I +V SS+ G + + + YS +K A+ G ++ + Sbjct: 131 YVVMSTAALP-MLKQSNGSI----AVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 Query: 166 IQQGIRCN---CVCPGTVDTPSLQERIQ----ARGNPEE 197 + + CV G +DT + + I A+ +P+E Sbjct: 186 YITKVNVSITLCVL-GLIDTETAMKEISGIINAQASPKE 223 >3GRK-A nrPDB Length = 293 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 53/203 (26%), Positives = 84/203 (41%), Gaps = 29/203 (14%) Query: 58 DVTKKKQIDQFANEVER----LDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVRSM 109 DV ID +E+ LD L + GF G +D E ++ +M ++V S+ Sbjct: 89 DVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYSL 148 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + K++A G+I+ ++ + K + N V KAA+ K +A D Q Sbjct: 149 -TAVSRRAEKLMAD-GGSILTLTYYGAE-KVMPNYNVMGVAKAALEASVKYLAVDLGPQN 205 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDF---LKRQKTG----RFATAEEIAMLCV 222 IR N + G + T + A G DF LK + R T +E+ + + Sbjct: 206 IRVNAISAGPIKT------LAASG-----IGDFRYILKWNEYNAPLRRTVTIDEVGDVGL 254 Query: 223 YLASDESAYVTGNPVIIDGGWSL 245 Y SD S VTG D G+ + Sbjct: 255 YFLSDLSRSVTGEVHHADSGYHV 277 >1MG5-A nrPDB Length = 255 Score = 34.3 bits (77), Expect = 0.054, Method: Compositional matrix adjust. Identities = 54/192 (28%), Positives = 78/192 (40%), Gaps = 21/192 (10%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAK--VIATDI-NESKLQELEK---------YPG 51 L K +I A GIG + + K VI I N + + EL+ YP Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPY 63 Query: 52 IQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLN-VRSMY 110 T + T K FA +++ +DVL N AG +LD + + ++N + + Sbjct: 64 DVTVPIAETTKLLKTIFA-QLKTVDVLINGAG------ILDDHQIERTIAVNYTGLVNTT 116 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 I F K G I N+ SV + + VYS TKAAV+ T S+A G+ Sbjct: 117 TAILDFWDKRKGGPGGIICNIGSV-TGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGV 175 Query: 171 RCNCVCPGTVDT 182 V PG T Sbjct: 176 TAYTVNPGITRT 187 >5WQO-A nrPDB Length = 234 Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 25/191 (13%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIAT---DINESKLQELEKYPG--IQTRVLDVTKK- 62 +++ A++GIG A AF + GA+V A LQ L + G +Q D+ + Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 Query: 63 --KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 ++I + E R+D L AG ++ D E D + + L + A P Sbjct: 69 CAERIGEMLGE-RRIDRLIVNAG-IYGPQQQDVAEIDAEQTAQL------FLTNAIAPLR 120 Query: 121 LAQ-------KSGNIINMSS-VASSVKGV-VNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 LA+ + G + MSS +AS G+ +Y +KAA+ L +S +F + Sbjct: 121 LARALSGRVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFS 180 Query: 172 CNCVCPGTVDT 182 + PG V T Sbjct: 181 LLLLHPGWVRT 191 >4NK4-A nrPDB Length = 301 Score = 31.2 bits (69), Expect = 0.46, Method: Compositional matrix adjust. Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 7/126 (5%) Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 L G +I ++ S++ V N + K+A+ TK +A D+ IR N + G V Sbjct: 168 LMPHGGAMITLT-YGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNIRINAISAGPV 226 Query: 181 DTPSLQERIQARGNPEEAR-NDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 T + R ++ N LKR + E+I +YL S S VTG + Sbjct: 227 RTLAGASISNGRDIAAWSKENSPLKRT-----VSLEDIGNSALYLLSYLSNGVTGEIHYV 281 Query: 240 DGGWSL 245 D G+++ Sbjct: 282 DCGYNI 287 >4J3F-A nrPDB Length = 280 Score = 31.2 bits (69), Expect = 0.48, Method: Compositional matrix adjust. Identities = 55/266 (20%), Positives = 111/266 (41%), Gaps = 38/266 (14%) Query: 1 MGRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKLQELEK----YPGIQT 54 MG L GK I++T + + I A A REGA++ T + + K +EK + Sbjct: 21 MGFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFK-DRVEKLCAEFNPAAV 79 Query: 55 RVLDVTKKKQIDQFANEVER----LDVLFNVAGFVH----HGTVLDCEEKD-WDFSMNLN 105 DV ++I E+ + LD + + F G +DC ++ + + +++ Sbjct: 80 LPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDIS 139 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S + K M+ ++ +++ ++ + + K + + KA++ + A Sbjct: 140 AYSFAALAKEG-RSMMKNRNASMVALTYIGAE-KAMPSYNTMGVAKASLEATVRYTALAL 197 Query: 166 IQQGIRCNCVCPGTVDT------PSLQERI--QARGNPEEARNDFLKRQKTGRFATAEEI 217 + GI+ N V G + T + ++ + A +P + D ++ T + Sbjct: 198 GEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNT--------V 249 Query: 218 AMLCVYLASDESAYVTGNPVIIDGGW 243 A LC SD + +TG V +D G+ Sbjct: 250 AFLC----SDMATGITGEVVHVDAGY 271 >5K1S-A nrPDB Length = 362 Score = 30.4 bits (67), Expect = 0.71, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 29/43 (67%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK 48 G+ +++T A+ G+G ++ +GA+VIA +E+K+Q L++ Sbjct: 184 GETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKE 226 >1OAA-A nrPDB Length = 259 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 53/214 (24%), Positives = 95/214 (44%), Gaps = 30/214 (14%) Query: 8 VIILTAAAQGIGQAAALAFAR---EGAKVIATDINESKLQELEKYPGIQTRVL------- 57 V +LT A++G G+A A AR G+ ++ + +ES L++L++ G Q L Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 58 DVTKKKQIDQFANEV---------ERLDVLFNVA--GFVHHG--TVLDCEEKDWDFSMNL 104 D+ + + + + V +RL ++ N A G V G V D E + +++NL Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 127 Query: 105 NVRSMYLMIKAFLPKMLAQK--SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA 162 SM + L S ++N+SS+ +++ +Y KAA L + +A Sbjct: 128 T--SMLCLTSGTLNAFQDSPGLSKTVVNISSLC-ALQPYKGWGLYCAGKAARDMLYQVLA 184 Query: 163 ADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPE 196 A+ + +R PG +D Q + +PE Sbjct: 185 AE--EPSVRVLSYAPGPLDNDMQQLARETSKDPE 216 >3VPX-A nrPDB Length = 364 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 3/36 (8%) Query: 12 TAAAQGIGQAA-ALA--FAREGAKVIATDINESKLQ 44 T A QG+G A AL EGAK+I TDINE +Q Sbjct: 175 TVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQ 210 >3OJO-A nrPDB Length = 431 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 7/50 (14%) Query: 11 LTAAAQG-IGQAAALAFAREGAKVIATDINESKLQELE------KYPGIQ 53 LT G IG ++ FA+ G V+ DIN+ + +L+ + PG+Q Sbjct: 14 LTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQ 63 >4IZE-A nrPDB Length = 152 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%) Query: 176 CPGTVDTPSLQERIQA----RGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 C + P+LQ + Q G PE + R KTGR +T E +A ++AS + Sbjct: 71 CEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFIASSK 127 >2CVJ-A nrPDB Length = 180 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGI 52 VI++ G+ +AAL AR G KV+ D SK++ + + YPG+ Sbjct: 4 VIVVGGGPSGL--SAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGL 49 >3O26-A nrPDB Length = 311 Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Query: 147 YSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 Y+T+KA + T+ +A + + NCVCPG V T Sbjct: 236 YTTSKACLNAYTRVLANKIPK--FQVNCVCPGLVKT 269 >6ACF-A nrPDB Length = 367 Score = 28.1 bits (61), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 7/40 (17%) Query: 4 LDGKVIILTAAAQGIGQAA---ALAFAREGAKVIATDINE 40 L+GKV+ A QG+G A EGAK+I TDIN+ Sbjct: 171 LEGKVV----AVQGVGNVAYHLCRHLHEEGAKLIVTDINK 206 >1EDZ-A nrPDB Length = 320 Score = 27.3 bits (59), Expect = 6.1, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN 39 RL GK I+ ++ +G+ A A +GA V + D+N Sbjct: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 >4XT6-A nrPDB Length = 258 Score = 26.9 bits (58), Expect = 7.7, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%) Query: 143 NRCVYSTTKAAVIGLTKSVAADFIQQG-------IRCNCVCPGTVDTPSLQERIQARG 193 + V++ T+ A + LT + AD +Q I C+ PGTVD L ++ ARG Sbjct: 129 DMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARG 186 >5JE5-A nrPDB Length = 247 Score = 26.9 bits (58), Expect = 7.9, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 18/97 (18%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKY-PGIQTR 55 +G + GK ++ A G G + R AKV+ DI+E + +E KY ++ Sbjct: 37 IGDVSGKSVLDLAC--GFGFFGREIYRRGAAKVVGVDISEKMIELAREESRKYGDPLEFH 94 Query: 56 VLDVTKKKQIDQF-----------ANEVERLDVLFNV 81 V DV + + QF A+ VE L +F V Sbjct: 95 VRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKV 131 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2AG5-A nrPDB 320 3e-88 2PNF-A nrPDB 266 5e-72 3RSH-A nrPDB 257 3e-69 4JRO-A nrPDB 257 4e-69 2HQ1-A nrPDB 253 5e-68 2UVD-A nrPDB 253 7e-68 3F9I-A nrPDB 253 7e-68 3EMK-A nrPDB 252 7e-68 1Q7C-A nrPDB 250 3e-67 4M8S-A nrPDB 249 7e-67 2C07-A nrPDB 249 8e-67 3LYL-A nrPDB 249 1e-66 3OSU-A nrPDB 248 2e-66 5CDY-A nrPDB 247 2e-66 5ITV-A nrPDB 247 3e-66 3GRP-A nrPDB 247 4e-66 1AE1-A nrPDB 246 5e-66 3FTP-A nrPDB 245 2e-65 3WOH-A nrPDB 244 2e-65 4NBT-A nrPDB 243 6e-65 4BO1-A nrPDB 236 9e-63 2NM0-A nrPDB 233 7e-62 4NBV-A nrPDB 233 7e-62 2PH3-A nrPDB 232 9e-62 4DMM-A nrPDB 232 9e-62 4KMS-A nrPDB 232 1e-61 2EW8-A nrPDB 229 9e-61 2AE2-A nrPDB 228 2e-60 3OEC-A nrPDB 228 2e-60 1GEE-A nrPDB 228 2e-60 4K6F-A nrPDB 226 5e-60 5U9P-A nrPDB 226 6e-60 4IIN-A nrPDB 226 6e-60 4RZH-A nrPDB 226 7e-60 2Q2Q-A nrPDB 226 7e-60 3AUT-A nrPDB 225 2e-59 3O4R-A nrPDB 225 2e-59 1YXM-A nrPDB 224 3e-59 5OVL-A nrPDB 223 4e-59 5YSS-A nrPDB 223 6e-59 3W8F-A nrPDB 223 7e-59 1NFF-A nrPDB 222 8e-59 2ZAT-A nrPDB 222 1e-58 1O5I-A nrPDB 222 1e-58 1X1T-A nrPDB 222 1e-58 4CQL-A nrPDB 221 1e-58 1GEG-A nrPDB 221 2e-58 6CI9-A nrPDB 220 3e-58 5OJG-A nrPDB 220 3e-58 3EZL-A nrPDB 220 4e-58 5VT6-A nrPDB 220 4e-58 2CDH-G nrPDB 220 4e-58 4Z9Y-A nrPDB 220 5e-58 3UVE-A nrPDB 220 6e-58 5OVJ-A nrPDB 218 1e-57 3WYE-A nrPDB 218 2e-57 3VZS-A nrPDB 216 5e-57 3D3W-A nrPDB 216 6e-57 5T5Q-A nrPDB 216 8e-57 6NRP-A nrPDB 214 3e-56 4AVY-A nrPDB 212 8e-56 1UZM-A nrPDB 212 1e-55 3V2H-A nrPDB 212 1e-55 4CQM-B nrPDB 211 2e-55 1AHH-A nrPDB 211 2e-55 4RZI-B nrPDB 211 3e-55 3V2G-A nrPDB 210 4e-55 1K2W-A nrPDB 210 4e-55 4IS3-A nrPDB 210 6e-55 3OIC-A nrPDB 207 3e-54 3RWB-A nrPDB 207 3e-54 4HP8-A nrPDB 206 5e-54 4MOW-A nrPDB 206 6e-54 4DBZ-A nrPDB 206 7e-54 3A28-C nrPDB 205 1e-53 2CFC-A nrPDB 205 2e-53 3UF0-A nrPDB 204 3e-53 4E6P-A nrPDB 204 3e-53 2P91-A nrPDB 203 5e-53 4IIV-A nrPDB 203 8e-53 3WTC-A nrPDB 202 9e-53 3R3S-A nrPDB 202 1e-52 1DOH-A nrPDB 202 1e-52 1CYD-A nrPDB 202 1e-52 3T7C-A nrPDB 202 1e-52 5EJ2-A nrPDB 201 2e-52 2FWM-X nrPDB 200 3e-52 1HXH-A nrPDB 200 5e-52 2B4Q-A nrPDB 199 9e-52 3U5T-A nrPDB 199 1e-51 3GDF-A nrPDB 198 3e-51 2HSD-A nrPDB 197 3e-51 5JS6-A nrPDB 197 4e-51 3UN1-A nrPDB 196 7e-51 5B1Y-A nrPDB 196 1e-50 4FC7-A nrPDB 195 2e-50 3U4C-A nrPDB 189 1e-48 4TRR-A nrPDB 189 1e-48 3V8B-A nrPDB 187 3e-48 4EGF-A nrPDB 185 1e-47 2BGM-A nrPDB 185 1e-47 5O3Z-A nrPDB 185 2e-47 4M89-A nrPDB 184 3e-47 3OIG-A nrPDB 182 9e-47 1H5Q-A nrPDB 182 1e-46 4ZJU-A nrPDB 182 1e-46 5CFZ-A nrPDB 182 1e-46 5JY1-A nrPDB 181 3e-46 4JQC-A nrPDB 180 6e-46 5TF4-A nrPDB 179 1e-45 4NR0-A nrPDB 178 1e-45 3PXX-A nrPDB 178 2e-45 4CR6-A nrPDB 178 2e-45 5YCX-A nrPDB 178 2e-45 2YW9-A nrPDB 177 4e-45 3ZV3-A nrPDB 176 7e-45 4RGB-A nrPDB 176 8e-45 1BDB-A nrPDB 174 2e-44 5KOI-A nrPDB 174 3e-44 2X9N-A nrPDB 173 5e-44 4GKB-A nrPDB 173 6e-44 5I9N-A nrPDB 173 8e-44 3GRK-A nrPDB 171 2e-43 2O23-A nrPDB 170 5e-43 4ALL-A nrPDB 169 1e-42 3OML-A nrPDB 168 1e-42 3K2E-A nrPDB 166 5e-42 3RKU-A nrPDB 166 1e-41 1E3W-A nrPDB 164 2e-41 5IZ4-A nrPDB 163 8e-41 2GDZ-A nrPDB 163 9e-41 4DA9-A nrPDB 159 8e-40 1W73-A nrPDB 156 1e-38 2NWQ-A nrPDB 153 5e-38 1A27-A nrPDB 153 5e-38 1P33-A nrPDB 153 6e-38 6CGE-A nrPDB 152 1e-37 2PD3-A nrPDB 150 5e-37 2QHX-A nrPDB 148 2e-36 2BFA-A nrPDB 148 2e-36 3E9N-A nrPDB 143 9e-35 3PPI-A nrPDB 139 9e-34 4DRY-A nrPDB 137 4e-33 5PGZ-A nrPDB 135 2e-32 3DWF-A nrPDB 135 2e-32 2DKN-A nrPDB 133 6e-32 1FJH-A nrPDB 133 8e-32 5ILO-A nrPDB 131 4e-31 4HBG-A nrPDB 128 2e-30 3UCF-A nrPDB 128 3e-30 3U9L-A nrPDB 126 9e-30 1SNY-A nrPDB 123 7e-29 5TQV-A nrPDB 118 2e-27 3KZV-A nrPDB 118 2e-27 1B15-A nrPDB 111 4e-25 Sequences not found previously or not previously below threshold: 4J3F-A nrPDB 165 1e-41 4NK4-A nrPDB 150 4e-37 2O2S-A nrPDB 120 5e-28 4Q9N-A nrPDB 119 1e-27 1ENP-A nrPDB 117 5e-27 2NTV-A nrPDB 110 5e-25 2HRB-A nrPDB 110 5e-25 4OYR-A nrPDB 110 7e-25 5L51-A nrPDB 105 2e-23 2PTG-A nrPDB 104 3e-23 3BHI-A nrPDB 102 1e-22 1N5D-A nrPDB 101 2e-22 3F4B-A nrPDB 99 2e-21 1MG5-A nrPDB 99 2e-21 3O26-A nrPDB 97 5e-21 5LCX-A nrPDB 94 4e-20 5WQO-A nrPDB 90 1e-18 2O2Y-A nrPDB 89 1e-18 4Z3K-A nrPDB 86 2e-17 4HWK-A nrPDB 86 2e-17 1OAA-A nrPDB 79 2e-15 2PK3-A nrPDB 64 5e-11 4LIS-A nrPDB 64 5e-11 1DIR-A nrPDB 61 6e-10 3ORF-A nrPDB 58 5e-09 1OOE-A nrPDB 57 6e-09 1Z45-A nrPDB 53 9e-08 3SLK-A nrPDB 53 9e-08 1VL0-A nrPDB 52 3e-07 2Q1W-A nrPDB 52 3e-07 6BWL-A nrPDB 51 6e-07 2NNL-D nrPDB 50 8e-07 1UDA-A nrPDB 49 1e-06 3RFT-A nrPDB 49 2e-06 1I3M-A nrPDB 49 2e-06 4G5H-A nrPDB 48 3e-06 2GN9-A nrPDB 47 8e-06 1ZZE-A nrPDB 45 2e-05 5K1S-A nrPDB 45 4e-05 4PVC-A nrPDB 45 4e-05 3ENK-A nrPDB 44 4e-05 1RKX-A nrPDB 44 6e-05 5B6K-A nrPDB 43 9e-05 1R66-A nrPDB 42 2e-04 3SXP-A nrPDB 42 2e-04 2PZM-A nrPDB 42 2e-04 1GY8-A nrPDB 42 3e-04 4J90-A nrPDB 41 4e-04 3SC6-A nrPDB 41 4e-04 4K28-A nrPDB 41 6e-04 4R1T-A nrPDB 41 7e-04 5BUT-A nrPDB 41 7e-04 2HMT-A nrPDB 40 8e-04 4KDR-A nrPDB 40 0.001 1GPJ-A nrPDB 40 0.001 2HUN-A nrPDB 40 0.001 6ACF-A nrPDB 40 0.001 3OND-A nrPDB 40 0.001 6GCS-E nrPDB 40 0.001 1WVG-A nrPDB 40 0.001 4KDC-A nrPDB 40 0.001 1OC2-A nrPDB 40 0.001 4KTT-E nrPDB 40 0.001 3NJ4-A nrPDB 39 0.001 1BXK-A nrPDB 39 0.001 4J2O-A nrPDB 39 0.001 3VPX-A nrPDB 39 0.002 1KEU-A nrPDB 39 0.003 2Z95-A nrPDB 39 0.003 1LU9-A nrPDB 39 0.003 3HFS-A nrPDB 38 0.003 5JXW-A nrPDB 38 0.003 2C54-A nrPDB 38 0.004 6GBN-A nrPDB 37 0.005 4WPG-A nrPDB 37 0.005 5N2I-A nrPDB 37 0.006 1O89-A nrPDB 36 0.011 6G2J-P nrPDB 36 0.017 4EUF-A nrPDB 36 0.017 3PVZ-A nrPDB 35 0.025 6DEB-A nrPDB 35 0.026 5INT-A nrPDB 35 0.027 4A10-A nrPDB 35 0.037 3WMX-A nrPDB 35 0.037 4EJ6-A nrPDB 34 0.041 2EER-A nrPDB 34 0.041 2C20-A nrPDB 34 0.044 6ACQ-A nrPDB 34 0.045 3DFZ-A nrPDB 34 0.049 1E3J-A nrPDB 34 0.052 4KUG-A nrPDB 34 0.053 4YUC-A nrPDB 34 0.057 4EJ0-A nrPDB 34 0.063 3N58-A nrPDB 34 0.063 4WLE-A nrPDB 34 0.069 2BKA-A nrPDB 34 0.083 2HK7-A nrPDB 34 0.087 5F5N-A nrPDB 33 0.095 1RPN-A nrPDB 33 0.096 3H9U-A nrPDB 33 0.097 4XRR-A nrPDB 33 0.097 2GAS-A nrPDB 33 0.10 4J6F-A nrPDB 33 0.11 5EGS-A nrPDB 33 0.12 2GGS-A nrPDB 33 0.12 2EXX-A nrPDB 33 0.13 4PZE-A nrPDB 33 0.15 3R0Q-C nrPDB 32 0.16 2VN8-A nrPDB 32 0.16 4N18-A nrPDB 32 0.18 1MLD-A nrPDB 32 0.19 5M65-A nrPDB 32 0.20 7REQ-A nrPDB 32 0.21 3LK7-A nrPDB 32 0.21 1F3L-A nrPDB 32 0.21 4BKP-A nrPDB 32 0.23 3PEF-A nrPDB 32 0.23 3F6S-A nrPDB 32 0.29 6CU3-A nrPDB 32 0.30 5GXF-A nrPDB 32 0.30 3RI6-A nrPDB 32 0.31 3DMF-A nrPDB 32 0.33 5GUP-L nrPDB 31 0.35 3X2F-A nrPDB 31 0.35 4A6N-B nrPDB 31 0.37 4E0B-A nrPDB 31 0.38 5LV5-A nrPDB 31 0.38 6C55-A nrPDB 31 0.39 2Q4B-A nrPDB 31 0.40 2RIR-A nrPDB 31 0.40 2X86-A nrPDB 31 0.48 3G1U-A nrPDB 31 0.50 2WEK-A nrPDB 31 0.54 1YB5-A nrPDB 31 0.55 5ENV-A nrPDB 31 0.57 1V8B-A nrPDB 31 0.60 1EDZ-A nrPDB 31 0.61 1EQ2-A nrPDB 31 0.64 1ZCJ-A nrPDB 31 0.65 6BI4-A nrPDB 31 0.69 4WEQ-A nrPDB 31 0.70 5YWN-A nrPDB 31 0.73 3BIC-A nrPDB 30 0.80 2DFV-A nrPDB 30 0.81 6BII-A nrPDB 30 0.84 3FBG-A nrPDB 30 0.85 5A3V-A nrPDB 30 0.88 4WOK-A nrPDB 30 0.89 4OM8-A nrPDB 30 0.89 3ZWA-A nrPDB 30 0.90 4DZR-A nrPDB 30 0.97 1NHQ-A nrPDB 30 1.0 5ZZM-A nrPDB 30 1.1 3PII-A nrPDB 30 1.1 1UUF-A nrPDB 30 1.1 3H0K-A nrPDB 30 1.2 1C0L-A nrPDB 30 1.2 3IP1-A nrPDB 30 1.2 6APH-A nrPDB 29 1.3 1XDW-A nrPDB 29 1.3 5NUE-A nrPDB 29 1.4 1ZDL-A nrPDB 29 1.5 4TSK-A nrPDB 29 1.6 1IE3-A nrPDB 29 1.6 3TQH-A nrPDB 29 1.7 4B4V-A nrPDB 29 1.7 5KIA-A nrPDB 29 1.8 6H0D-A nrPDB 29 1.9 2YQ5-A nrPDB 29 2.0 3R9I-A nrPDB 29 2.1 4MOP-A nrPDB 29 2.1 3D64-A nrPDB 29 2.2 1JAY-A nrPDB 29 2.3 1NLM-A nrPDB 29 2.4 6CAU-A nrPDB 29 2.4 2BC1-A nrPDB 29 2.5 1LLU-A nrPDB 29 2.5 3HDH-A nrPDB 29 2.8 5TC4-A nrPDB 29 2.9 1F14-A nrPDB 28 3.1 1PGJ-A nrPDB 28 3.3 4R16-A nrPDB 28 3.7 1NPY-A nrPDB 28 3.8 6C6P-A nrPDB 28 3.9 1DB3-A nrPDB 28 3.9 3DQQ-A nrPDB 28 4.1 1X74-A nrPDB 28 4.2 4H05-A nrPDB 28 4.5 3K96-A nrPDB 28 4.5 4UUP-A nrPDB 28 4.9 4DVJ-A nrPDB 27 5.0 6DKH-A nrPDB 27 5.1 1YXY-A nrPDB 27 5.2 1QYC-A nrPDB 27 5.7 3F6T-A nrPDB 27 6.0 2QVR-A nrPDB 27 6.1 4EEZ-A nrPDB 27 6.3 2ZJ1-A nrPDB 27 6.7 3K30-A nrPDB 27 6.8 1EZ1-A nrPDB 27 6.8 3ORR-A nrPDB 27 7.9 5E9F-A nrPDB 27 7.9 4B3J-A nrPDB 27 7.9 2XHZ-A nrPDB 27 8.4 2MSW-A nrPDB 27 8.4 4A5O-A nrPDB 27 8.8 5ZKP-A nrPDB 27 8.9 5U9C-A nrPDB 27 9.0 3AOE-A nrPDB 27 9.5 5G6R-A nrPDB 27 9.6 >2AG5-A nrPDB Length = 246 Score = 320 bits (821), Expect = 3e-88, Method: Composition-based stats. Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM Sbjct: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV Sbjct: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID Sbjct: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 Query: 241 GGWSL 245 GGWSL Sbjct: 241 GGWSL 245 >2PNF-A nrPDB Length = 248 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 129/251 (51%), Gaps = 17/251 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG------IQTRV 56 +L GKV ++T + +GIG+A A A G+ VI T + + + + + Sbjct: 4 KLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVE 63 Query: 57 LDVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +++ ++ I++ E V+ +D+L N AG L DW+ + +N+ +L+ Sbjct: 64 MNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLV 123 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + L KM+ Q+ G I+N+SSV G V + YSTTKA +IG TKS+A + + + Sbjct: 124 TQNSLRKMIKQRWGRIVNISSVVG-FTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N V PG ++T EE + + ++ GRF + EE+A + ++L S+ ++Y+ Sbjct: 183 NAVAPGFIETDMTAVL------SEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYI 236 Query: 233 TGNPVIIDGGW 243 TG + ++GG Sbjct: 237 TGEVIHVNGGM 247 >3RSH-A nrPDB Length = 251 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 83/250 (33%), Positives = 130/250 (52%), Gaps = 13/250 (5%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDV 59 L+GKV ++T A++GIG+A A A GAKVI T +ES Q + Y G + L+V Sbjct: 8 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNV 67 Query: 60 TKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T + I+ E +D+L N AG ++ +E++W M N+ S++ + KA Sbjct: 68 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 127 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 L M+ ++ G IIN+ SV ++ G + Y+ KA VIG TKS+A + +G+ N V Sbjct: 128 VLRGMMKKRQGRIINVGSVVGTM-GNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTV 186 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG ++T + +E R L + GR EIA +LAS E+AY+TG Sbjct: 187 APGFIETDM------TKALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGE 240 Query: 236 PVIIDGGWSL 245 + ++GG + Sbjct: 241 TLHVNGGMYM 250 >4JRO-A nrPDB Length = 271 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 78/252 (30%), Positives = 128/252 (50%), Gaps = 17/252 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE----LEKYPGIQTRVL-- 57 L GKV ++T ++GIG+ A+ A+EGA + + E L G++ + Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAMKA 86 Query: 58 DVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 +V + +D F + R+D+L N AG ++ +E +WD +N+N++ +L Sbjct: 87 NVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFLCT 146 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 KA M+ Q++G IINM+SV + G + Y +KA VIGLTK+ A + +GI N Sbjct: 147 KAVSRTMMKQRAGKIINMASVVGLI-GNAGQANYVASKAGVIGLTKTTARELAPRGINVN 205 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + T + E+ + L + G + T E+IA ++LASD S Y+T Sbjct: 206 AVAPGFITTDMTDKL------DEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYIT 259 Query: 234 GNPVIIDGGWSL 245 G + +DGG + Sbjct: 260 GQTLSVDGGMVM 271 >2HQ1-A nrPDB Length = 247 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 87/254 (34%), Positives = 128/254 (50%), Gaps = 17/254 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE----SKLQELEKYPGIQTRVL 57 +L GK I+T +++G+G+A A GA ++ E K GI V Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 58 --DVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV + ++ R+D+L N AG +L EKDWD +N N++S YL Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYL 120 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 KA ML QKSG IIN++S+A + G + Y+ +KA +IG TKS+A +F +GI Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGII-GNAGQANYAASKAGLIGFTKSIAKEFAAKGIY 179 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 CN V PG + T P++ + +L RF T EE+A + +LASD+S Y Sbjct: 180 CNAVAPGIIKTDMTDVL------PDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 232 VTGNPVIIDGGWSL 245 +TG + IDGG + Sbjct: 234 ITGQVINIDGGLVM 247 >2UVD-A nrPDB Length = 246 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 125/252 (49%), Gaps = 17/252 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-----LQELEKYPGIQTRV-L 57 L GKV ++T A++GIG+A A+ A++GA V+ + + E++K V Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 58 DVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DV + + + ++D+L N AG ++ +E++WD +N N++ ++L Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLCT 121 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 KA M+ Q+ G I+N++SV V G + Y KA VIGLTK+ A + + I N Sbjct: 122 KAVSRFMMRQRHGRIVNIASVVG-VTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVN 180 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 + PG + T E + + LK +F A++IA + ASD+S Y+T Sbjct: 181 AIAPGFIATDMTDVL------DENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYIT 234 Query: 234 GNPVIIDGGWSL 245 G + +DGG + Sbjct: 235 GQTLNVDGGMVM 246 >3F9I-A nrPDB Length = 249 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 66/247 (26%), Positives = 129/247 (52%), Gaps = 9/247 (3%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYP--GIQTRVLD 58 M L GK ++T A+ GIG A A + G+KVI + NE KL+ L V + Sbjct: 9 MIDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCN 68 Query: 59 VTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 + K++ ++ LD+L AG + +++D+D +++N+++ +++ + + Sbjct: 69 LANKEECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIK 128 Query: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPG 178 KM+ ++ G IIN+SS+ + G + Y +KA +IG+TKS++ + +GI N V PG Sbjct: 129 KMIQKRYGRIINISSIVG-IAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPG 187 Query: 179 TVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVI 238 + + + E+ R +++ G + E++A +LAS+ ++Y+TG + Sbjct: 188 FIKSDMTDKL------NEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTLH 241 Query: 239 IDGGWSL 245 ++GG + Sbjct: 242 VNGGMLM 248 >3EMK-A nrPDB Length = 246 Score = 252 bits (645), Expect = 7e-68, Method: Composition-based stats. Identities = 70/251 (27%), Positives = 128/251 (50%), Gaps = 13/251 (5%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV--LD 58 M L G+ ++T A G+G+A A A +GA V E KL+EL G + V + Sbjct: 2 MFDLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPAN 61 Query: 59 VTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ ++ + E+ +D+L N AG G + ++DWD + +N+ S++ + + Sbjct: 62 LSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTR 121 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 M+ +++G IIN++S+ V G + Y +KA +IG +KS+A + + + NC Sbjct: 122 ELTHPMMRRRNGRIINITSIVG-VTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNC 180 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG +++ + E+ ++ + R +IA VYLASDE+AYVTG Sbjct: 181 IAPGFIESAMTGKL------NEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTG 234 Query: 235 NPVIIDGGWSL 245 + ++GG ++ Sbjct: 235 QTLHVNGGMAM 245 >1Q7C-A nrPDB Length = 244 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 76/248 (30%), Positives = 132/248 (53%), Gaps = 13/248 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDVTK 61 +GK+ ++T A++GIG+A A A GAKVI T +E+ Q + Y G + +L+VT Sbjct: 3 FEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTD 62 Query: 62 KKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 I+ E +D+L N AG ++ ++++W+ + N+ S++ + KA + Sbjct: 63 PASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVM 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G II + SV ++ G + ++ KA +IG +KS+A + +GI N V P Sbjct: 123 RAMMKKRHGRIITIGSVVGTM-GNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVAP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G ++T R ++ R L + GR A+EIA +LASDE+AY+TG + Sbjct: 182 GFIETDM------TRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETL 235 Query: 238 IIDGGWSL 245 ++GG + Sbjct: 236 HVNGGMYM 243 >4M8S-A nrPDB Length = 248 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 86/249 (34%), Positives = 137/249 (55%), Gaps = 14/249 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYP---GIQTRVLDVT 60 L GK+ ++T A++GIG A A A GAKVI T +ES + + G + RVL+ Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSA 65 Query: 61 KKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + + ++ +LD+L N AG ++ +E++WD M +N++S++ KA Sbjct: 66 EPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKAV 125 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 L M+ Q++G IIN++SV V G + Y+ KA +IG +KS+A + +GI NCV Sbjct: 126 LRGMMKQRAGRIINITSVVG-VMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCVA 184 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 PG +DT R PEE R F + GRF A++IA ++LASD++ Y+TG Sbjct: 185 PGFIDTDM------TRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQT 238 Query: 237 VIIDGGWSL 245 + ++GG + Sbjct: 239 LHVNGGMLM 247 >2C07-A nrPDB Length = 285 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 128/249 (51%), Gaps = 16/249 (6%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN----ESKLQELEKYPGIQTRVL-DV 59 + KV ++T A +GIG+ A A+ + VI +S + E++ + + DV Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 60 TKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 +KK++I + N++ + +D+L N AG L + +W+ + N+ S++ + + Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQP 162 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +M+ + G IIN+SS+ + G V + YS++KA VIG TKS+A + + I N + Sbjct: 163 ISKRMINNRYGRIINISSIVG-LTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAI 221 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG + + + E+ + + + GR T EE+A L +L+SD+S Y+ G Sbjct: 222 APGFISSDMTDKI------SEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGR 275 Query: 236 PVIIDGGWS 244 +IDGG S Sbjct: 276 VFVIDGGLS 284 >3LYL-A nrPDB Length = 247 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 129/251 (51%), Gaps = 16/251 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---KYPGIQTR--VLD 58 L+ KV ++T A++GIG A A A +GA V+ T +++ ++ E K G + R VL+ Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLN 62 Query: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ + I F E++ +D+L N AG ++ E +W +N N+ S++ M K Sbjct: 63 ISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSK 122 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + M+ ++ G II++ SV S G + Y KA VIG +KS+A + + I N Sbjct: 123 ECVRGMMKKRWGRIISIGSVVGS-AGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNV 181 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG + T + +E ++ + +G+ ++IA +LAS+E+ Y+TG Sbjct: 182 VAPGFIATDMTDKLT------DEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITG 235 Query: 235 NPVIIDGGWSL 245 + ++GG + Sbjct: 236 QTLHVNGGMYM 246 >3OSU-A nrPDB Length = 246 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 118/249 (47%), Gaps = 17/249 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL------EKYPGIQTRVLDVT 60 K ++T A++GIG++ AL A EG V + E K +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 61 KKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 ++ E LDVL N AG ++ +E++WD ++ N++ ++ I+ Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 P+ML Q+SG IIN+SSV +V G + Y TKA VIGLTKS A + +GI N V Sbjct: 125 TPQMLRQRSGAIINLSSVVGAV-GNPGQANYVATKAGVIGLTKSAARELASRGITVNAVA 183 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 PG + + +E + L + RF +IA +LASD++ Y+TG Sbjct: 184 PGFIVSDMTDAL------SDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQT 237 Query: 237 VIIDGGWSL 245 + ++GG + Sbjct: 238 IHVNGGMYM 246 >5CDY-A nrPDB Length = 244 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 126/248 (50%), Gaps = 13/248 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDVTK 61 +GK+ ++T A++GIG+A A GA VI T +E + + Y G + +L+V Sbjct: 3 FEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVD 62 Query: 62 KKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 ID E +D+L N AG ++ ++ +W ++ N+ S++ + KA + Sbjct: 63 PTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVM 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G II + SV ++ G + Y+ KA VIG +KS+A + +GI N V P Sbjct: 123 RAMMKKRFGRIITIGSVVGTM-GNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVAP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G ++T + ++ R L + R A+EIA +LASDE++Y++G + Sbjct: 182 GFIETDMTRTLT------DDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGETL 235 Query: 238 IIDGGWSL 245 ++GG + Sbjct: 236 HVNGGMYM 243 >5ITV-A nrPDB Length = 255 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 85/252 (33%), Positives = 130/252 (51%), Gaps = 10/252 (3%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL---EKYPGIQTRVLD 58 L K +++T A GIG AA AF + A V+ DI+E++ + + E + D Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTD 62 Query: 59 VTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 +T + ++ + LDVL N AG + + E DW+ + +N+ M+LM K Sbjct: 63 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 122 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 L MLA GNIIN SV + + Y+ +K V+ LTKS+A D+ + IR NC Sbjct: 123 HALKHMLAAGKGNIINTCSV-GGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNC 181 Query: 175 VCPGTVDTPSLQERI--QARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 VCPG +DTP ++ G EE + + K R EEIA + ++LASD S+Y+ Sbjct: 182 VCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYM 241 Query: 233 TGNPVIIDGGWS 244 TG+ + DGG++ Sbjct: 242 TGSAITADGGYT 253 >3GRP-A nrPDB Length = 266 Score = 247 bits (630), Expect = 4e-66, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 128/251 (50%), Gaps = 13/251 (5%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV--LD 58 M +L G+ ++T A GIG+A A F +GA V E KL+E+ G V + Sbjct: 22 MFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSAN 81 Query: 59 VTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ +K I Q A E+E +D+L N AG G + +++DWD + +N+ + + + Sbjct: 82 LSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTR 141 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + M+ ++ G IIN++S+ V G + Y KA +IG +K++A + + I NC Sbjct: 142 ELIHSMMRRRYGRIINITSIVG-VVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNC 200 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + + + E+ + + R EEIA VYLASDE+AY+TG Sbjct: 201 IAPGFIKSAMTDKL------NEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTG 254 Query: 235 NPVIIDGGWSL 245 + I+GG ++ Sbjct: 255 QTLHINGGMAM 265 >1AE1-A nrPDB Length = 273 Score = 246 bits (629), Expect = 5e-66, Method: Composition-based stats. Identities = 73/251 (29%), Positives = 129/251 (51%), Gaps = 11/251 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGIQTRVLD 58 L G ++T ++GIG A A GA+V NE +L E EK ++ V D Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCD 78 Query: 59 VTKKKQIDQFANEV-----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + + + D+ V +L++L N AG V H D EKD++ M N + Y + Sbjct: 79 LLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLS 138 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 + P + A ++GN+I +SS+A + + +YS +K A+ +TKS+A ++ + IR N Sbjct: 139 QIAYPLLKASQNGNVIFLSSIAG-FSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVN 197 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + TP ++ I+ + +E ++F+ + GR +E++ L +L ++Y+T Sbjct: 198 SVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYIT 257 Query: 234 GNPVIIDGGWS 244 G + DGG++ Sbjct: 258 GQIIWADGGFT 268 >3FTP-A nrPDB Length = 270 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 79/251 (31%), Positives = 133/251 (52%), Gaps = 16/251 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---KYPGIQTR--VLD 58 LD +V I+T A++GIG+A AL AR GA VI T E+ + + K G++ R VL+ Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLN 85 Query: 59 VTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V +D E L+VL N AG + ++ +WD ++ N+++++ + + Sbjct: 86 VNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRLSR 145 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 A L M+ + G I+N++SV S G + Y+ KA V G+T+++A + +GI NC Sbjct: 146 AVLRPMMKARGGRIVNITSVVGS-AGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNC 204 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG +DT +G P+E + + GR + E+IA +LAS ++ Y+TG Sbjct: 205 VAPGFIDTDM------TKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITG 258 Query: 235 NPVIIDGGWSL 245 + ++GG + Sbjct: 259 TTLHVNGGMFM 269 >3WOH-A nrPDB Length = 251 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 83/254 (32%), Positives = 139/254 (54%), Gaps = 19/254 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ-----ELEKYPG-IQTR 55 G L GKV ++T ++G+G+A AL AR+GA V +++ E+E+ G ++ Sbjct: 7 GALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSY 66 Query: 56 VLDVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV+ +Q+ ++ +D+L N AG + G +++D+D MN N++ +L Sbjct: 67 RCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFL 126 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 IKA + ++SG+IIN+SSV+ V G + Y++ KA +IGLTKS+A + ++ +R Sbjct: 127 FIKACYFGFIRKRSGSIINISSVSG-VFGSAGQANYASAKAGLIGLTKSIAKELAERNVR 185 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 CN V PG + T Q+ + + L RF +E+A L +LA DES+Y Sbjct: 186 CNAVAPGLIATDMTQDLVDD--------SKRLDPVPMRRFGRPDEVAGLVAFLAGDESSY 237 Query: 232 VTGNPVIIDGGWSL 245 +TG V +DGG ++ Sbjct: 238 ITGQVVCVDGGMAM 251 >4NBT-A nrPDB Length = 240 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 85/251 (33%), Positives = 138/251 (54%), Gaps = 17/251 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 M +L+GKV ++T A+G+GQA ALA+A EGAKVIA D+ + +P ++ L+VT Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTY----SHPNVEGMYLNVT 56 Query: 61 KKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 +++F V ++D+L N AG E WD +++N++ ++ + + Sbjct: 57 DVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLV 116 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG--IRCNC 174 P+M G+IIN+SSV V G + + Y+ TKA VIGLT + A +F +G +R N Sbjct: 117 GPQMQTNGYGSIINISSVVG-VFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNA 175 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + T L+ P++ + F R EEIA + ++LASD+++YVTG Sbjct: 176 IAPGYIMTDILKTV------PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTG 229 Query: 235 NPVIIDGGWSL 245 + ++GG L Sbjct: 230 QTINVNGGMRL 240 >4BO1-A nrPDB Length = 269 Score = 236 bits (602), Expect = 9e-63, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 127/251 (50%), Gaps = 16/251 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR-----VLD 58 L GKV ++T A++GIGQA AL R GA VI T + S +++ + VLD Sbjct: 25 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLD 84 Query: 59 VTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V+ + + + + + ++ N AG ++ ++ +W +N N+ S+Y + K Sbjct: 85 VSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSK 144 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 A L M + G IIN+ SV ++ G + Y+ KA + G T+++A + + I N Sbjct: 145 AVLRGMTKARWGRIINIGSVVGAM-GNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNA 203 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG +DT +E PE R L + GR AEEIA + +LASD +AYVTG Sbjct: 204 VAPGFIDTDMTREL------PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTG 257 Query: 235 NPVIIDGGWSL 245 V ++GG + Sbjct: 258 ATVPVNGGMYM 268 >2NM0-A nrPDB Length = 253 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 68/243 (27%), Positives = 118/243 (48%), Gaps = 17/243 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A AFA G KV T + + G D+T +Q++ Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPE------GFLAVKCDITDTEQVE 75 Query: 67 QFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 Q E+ ++VL AG ++ E+D+ + N+ + ++K ML Sbjct: 76 QAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLR 135 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 K G ++ +SSV + G + Y+ +KA ++G +S+A + + I N V PG VDT Sbjct: 136 AKKGRVVLISSVVGLL-GSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVDT 194 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + +E R + + + GR+A EEIA +LASD+++Y+TG + +DGG Sbjct: 195 DMTKVLT------DEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGG 248 Query: 243 WSL 245 + Sbjct: 249 LGM 251 >4NBV-A nrPDB Length = 246 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 80/253 (31%), Positives = 128/253 (50%), Gaps = 16/253 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG-----IQTRV 56 +L G+V I+T AA GIG A A FA +GA V+ D+ E++++E + Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 57 LDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +DVT++ ++D V +R+D+L N AG + E +D +++N++ ++ Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNC 120 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 +A M Q G I+N SSV + G + Y+ +K VIG TK+ A + +G+R Sbjct: 121 AQAVAGLMTEQGKGVILNASSVVG-LYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRV 179 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N VCPG V+T LQ P++ + R A EIA + +LASD+++YV Sbjct: 180 NAVCPGFVNTEILQTV------PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYV 233 Query: 233 TGNPVIIDGGWSL 245 G + GG SL Sbjct: 234 NGVAIEASGGMSL 246 >2PH3-A nrPDB Length = 245 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 63/249 (25%), Positives = 123/249 (49%), Gaps = 18/249 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATD-------INESKLQELEKYPGIQTRVLDV 59 + ++T A++GIG+A AL A +G + ++ P + ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 60 TKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + + Q A + LD L N AG ++ +++DW+ + N+ +++ + Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + M+ + G I+N++SV + G + Y +KA +IG T++VA ++ Q+GI N V Sbjct: 122 AVKLMMKARFGRIVNITSVVG-ILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAV 180 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG ++T + P+E + +LK+ GRF EE+A +L S+++ Y+TG Sbjct: 181 APGFIETEMTERL------PQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQ 234 Query: 236 PVIIDGGWS 244 + +DGG + Sbjct: 235 TLCVDGGLT 243 >4DMM-A nrPDB Length = 269 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 80/253 (31%), Positives = 123/253 (48%), Gaps = 21/253 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV------L 57 L ++ ++T A++GIG+A AL A GAKV + + + Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKA 85 Query: 58 DVTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DV+++ +++ RLDVL N AG +L + DW ++LN+ ++L Sbjct: 86 DVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCS 145 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 +A ML Q+SG IIN++SV + G + YS KA VIGLTK+VA + +GI N Sbjct: 146 RAAAKIMLKQRSGRIINIASVVGEM-GNPGQANYSAAKAGVIGLTKTVAKELASRGITVN 204 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD-ESAYV 232 V PG + T E A L+ GR+ A E+A + +LA+D +AY+ Sbjct: 205 AVAPGFIATDMTSEL---------AAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYI 255 Query: 233 TGNPVIIDGGWSL 245 TG + IDGG + Sbjct: 256 TGQVINIDGGLVM 268 >4KMS-A nrPDB Length = 249 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 68/244 (27%), Positives = 119/244 (48%), Gaps = 13/244 (5%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDI-NESKLQELEKYPGIQTRVLDVTKKKQID 66 + I+T +GIG+A AL +G V+A N +E+E+ GI+T+ +V ++ Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCWNVADFEECR 71 Query: 67 QFANEVER-----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 Q E+E + +L N AG + +DW+ +N+N+ S + M + + +M Sbjct: 72 QAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQMR 131 Query: 122 AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVD 181 Q G I+N+SS+ + G V + YS KA +IG TK++A + + I NC+ PG + Sbjct: 132 NQDYGRIVNISSINAQ-AGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYIA 190 Query: 182 TPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDG 241 T + PE+ + R EEIA +L + + ++TG + I+G Sbjct: 191 TEMV------GAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISING 244 Query: 242 GWSL 245 G ++ Sbjct: 245 GHNM 248 >2EW8-A nrPDB Length = 249 Score = 229 bits (584), Expect = 9e-61, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 120/248 (48%), Gaps = 12/248 (4%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQ--TRVLDV 59 RL K+ ++T A GIG+A A FA EGA + D+ + E + G + T DV Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDV 63 Query: 60 TKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 ++ ++ F + R D+L N AG + + W + +NV S +LM KA Sbjct: 64 SQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMAKA 123 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 F+P M G IIN++S +K + Y +TKAA IG T+++A+D + GI N + Sbjct: 124 FVPGMKRNGWGRIINLTSTTYWLK-IEAYTHYISTKAANIGFTRALASDLGKDGITVNAI 182 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 P V T + + A + + L+ R ++ +LASD+++++TG Sbjct: 183 APSLVRTATTEA--SALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASFITGQ 238 Query: 236 PVIIDGGW 243 + +DGG Sbjct: 239 TLAVDGGM 246 >2AE2-A nrPDB Length = 260 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 67/250 (26%), Positives = 118/250 (47%), Gaps = 12/250 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGIQTRVLD 58 L+G ++T ++GIG A GA V N+ +L + K ++ V D Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCD 66 Query: 59 VTKKKQIDQFANEV-----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 ++ + + + N V +L++L N AG V + D +D+ M++N + Y + Sbjct: 67 LSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLS 126 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 P + A + GN++ +SSV+ ++ V VY TK A+ LT+ +A ++ + IR N Sbjct: 127 VLAHPFLKASERGNVVFISSVSGAL-AVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVN 185 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + T ++ IQ E N + R R +E+A + +L ++YVT Sbjct: 186 GVGPGVIATSLVEMTIQDPEQKEN-LNKLIDRCALRRMGEPKELAAMVAFLCFPAASYVT 244 Query: 234 GNPVIIDGGW 243 G + +DGG Sbjct: 245 GQIIYVDGGL 254 >3OEC-A nrPDB Length = 317 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 71/272 (26%), Positives = 121/272 (44%), Gaps = 30/272 (11%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI------------NESKLQEL-- 46 M RL GKV +T AA+G G+ A+ A++GA ++A D+ + +L+E Sbjct: 41 MNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVR 100 Query: 47 ---EKYPGIQTRVLDVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD 99 E+ I R DV + +D+ E +D+L + G + G V+ ++ W Sbjct: 101 LVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWS 160 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159 + N+ + +A LP M+ + G + S ++G + Y+ +K V GL Sbjct: 161 DILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLML 220 Query: 160 SVAADFIQQGIRCNCVCPGTVDTPS------LQERIQARGNPEEARNDFLKRQ---KTGR 210 S+A + + IR N V PG V+T L+ + NP L Q Sbjct: 221 SLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP 280 Query: 211 FATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + E+++ +LASDE+ Y+ G + +DGG Sbjct: 281 WVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >1GEE-A nrPDB Length = 261 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 126/253 (49%), Gaps = 16/253 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-----LQELEKYPGIQTRV-L 57 L+GKV+++T ++ G+G++ A+ FA E AKV+ ++ L+E++K G V Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 58 DVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DVT + + E +LDV+ N AG + + + DW+ ++ N+ +L Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 114 KAFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + + + G +INMSSV + Y+ +K + +T+++A ++ +GIR Sbjct: 125 REAIKYFVENDIKGTVINMSSVHEKIPW-PLFVHYAASKGGMKLMTETLALEYAPKGIRV 183 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N + PG ++TP E+ E R D G EEIA + +LAS E++YV Sbjct: 184 NNIGPGAINTPINAEKFA----DPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEASYV 239 Query: 233 TGNPVIIDGGWSL 245 TG + DGG +L Sbjct: 240 TGITLFADGGMTL 252 >4K6F-A nrPDB Length = 255 Score = 226 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 66/252 (26%), Positives = 117/252 (46%), Gaps = 16/252 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL------EKYPGIQTRVL 57 + ++ ++T G+G+A ++ G +V+ T + + + Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPV 68 Query: 58 DVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DV I++ +V +D+L N AG T+ ++ +WD + N+ S++ M Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT 128 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 K M+ + G I+N+SSV S KG V + Y+ KA + G TKS+A + ++G+ N Sbjct: 129 KPVCDGMVERGWGRIVNISSVNGS-KGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVN 187 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + T + Q + L + GR EE+A L YL S+E+ +VT Sbjct: 188 TVSPGYLATKMVTAIPQDILD-----TKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVT 242 Query: 234 GNPVIIDGGWSL 245 G+ + I+GG + Sbjct: 243 GSNIAINGGQHM 254 >5U9P-A nrPDB Length = 265 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 120/252 (47%), Gaps = 16/252 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK- 61 RLDG+ ++T + +GIG A A GA ++ D NE K L + + D Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF 76 Query: 62 --------KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + ID+F V +D+L N AG + E DW M +N+ ++ + Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVA 136 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 +A M+A+ G IIN+ SV S + Y+ TK AV LTK + AD+ + GI+ N Sbjct: 137 QAVARHMIARGHGKIINICSVQSEL-ARPTIAPYAATKGAVRMLTKGMCADWARYGIQAN 195 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFL-KRQKTGRFATAEEIAMLCVYLASDESAYV 232 + PG +T + + + A +D+L KR GR+ +E+ ++LAS S +V Sbjct: 196 GLAPGYFETELNRALVD-----DAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFV 250 Query: 233 TGNPVIIDGGWS 244 G + +DGG + Sbjct: 251 NGQTLFVDGGLT 262 >4IIN-A nrPDB Length = 271 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 62/254 (24%), Positives = 118/254 (46%), Gaps = 17/254 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ-----ELEKYPGIQTRV 56 + GK +++T A++GIG A A G KV + +++ ELE+ + Sbjct: 25 MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI 84 Query: 57 -LDVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 D + + I L L N AG V + + +D+ ++ N+ S ++ Sbjct: 85 KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI 144 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 + L M + G+++N++S+ +G + + YS +K +I ++KS A + + IR Sbjct: 145 GCREALKVMSKSRFGSVVNVASIIGE-RGNMGQTNYSASKGGMIAMSKSFAYEGALRNIR 203 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 N V PG ++T +E + D++K R +A+E+A +L SD S+Y Sbjct: 204 FNSVTPGFIETDMNANL------KDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSY 257 Query: 232 VTGNPVIIDGGWSL 245 +TG + ++GG + Sbjct: 258 ITGETLKVNGGLYM 271 >4RZH-A nrPDB Length = 247 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 82/256 (32%), Positives = 125/256 (48%), Gaps = 21/256 (8%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-----NESKLQELEKYPGIQTR 55 M L +V ++T A++GIG+A ALA A G KV+ ++ + E+ G Sbjct: 1 MTALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIA 60 Query: 56 V-LDVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 V +V ++DQ + R+DVL N AG +L + +DW ++LN+ ++ Sbjct: 61 VQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVF 120 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 L KA ML QKSG IIN++SVA + G + YS KA VIG TK+VA + +G+ Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVAG-MMGNPGQANYSAAKAGVIGFTKTVAKELASRGV 179 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD-ES 229 N V PG + T + L+ R+ EE+A +LA+D + Sbjct: 180 TVNAVAPGFIATDMTENLNA---------EPILQFIPLARYGQPEEVAGTIRFLATDPAA 230 Query: 230 AYVTGNPVIIDGGWSL 245 AY+TG +DGG + Sbjct: 231 AYITGQTFNVDGGMVM 246 >2Q2Q-A nrPDB Length = 255 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 77/252 (30%), Positives = 122/252 (48%), Gaps = 13/252 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK--LQELEKYPGIQTR-VLDVT 60 L GK ++T + GIG A AR GA ++ + L E+ ++ D++ Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLS 61 Query: 61 KKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 QI+ E +D+L N AG H V + WD + LN+ +++ + Sbjct: 62 DVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLA 121 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 LP M A+ G IIN++SV + G + Y K V+GLTK V + + CN +C Sbjct: 122 LPGMRARNWGRIINIASVHG-LVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAIC 180 Query: 177 PGTVDTPSLQERIQAR----GNPEEARNDFLK-RQKTGRFATAEEIAMLCVYLASDESAY 231 PG V TP +Q++I R G+P +A++D L +Q + F T E + L ++L S+ + Sbjct: 181 PGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQ 240 Query: 232 VTGNPVIIDGGW 243 V G +DGGW Sbjct: 241 VRGAAWNVDGGW 252 >3AUT-A nrPDB Length = 269 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 121/252 (48%), Gaps = 16/252 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL-----QELEKYPGIQTRV-L 57 L KV+++T + G+G+A A+ F +E AKV+ N + +E+E+ G V Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQG 72 Query: 58 DVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DVTK++ + E LDV+ N AG + + +W+ ++ N+ +L Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGS 132 Query: 114 KAFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + + + GN+INMSSV + Y+ +K + +T+++A ++ +GIR Sbjct: 133 REAIKYFVENDIKGNVINMSSVHEMIPW-PLFVHYAASKGGMKLMTETLALEYAPKGIRV 191 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N + PG ++TP E+ R D G EE+A + +LAS +++YV Sbjct: 192 NNIGPGAMNTPINAEKFA----DPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYV 247 Query: 233 TGNPVIIDGGWS 244 TG + DGG + Sbjct: 248 TGITLFADGGMT 259 >3O4R-A nrPDB Length = 261 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 125/249 (50%), Gaps = 15/249 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGIQTRVLD 58 L KV ++TA+ GIG A A A++GA V+ + + + + + + V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHH-GTVLDCEEKDWDFSMNLNVRSMYLMI 113 V K + ++ +D+L + A G+++D E+ WD ++++NV++ LM Sbjct: 73 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 132 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 KA +P+M + G+++ +SS+A+ Y+ +K A++GLTK++A + + IR N Sbjct: 133 KAVVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 191 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 C+ PG + T + + E + + R E+ A + +L S++++Y+T Sbjct: 192 CLAPGLIKTSFSRMLWMDKEKEESMKETL----RIRRLGEPEDCAGIVSFLCSEDASYIT 247 Query: 234 GNPVIIDGG 242 G V++ GG Sbjct: 248 GETVVVGGG 256 >1YXM-A nrPDB Length = 303 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 61/258 (23%), Positives = 108/258 (41%), Gaps = 18/258 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY------PGIQTR 55 G L G+V I+T A GIG+A G+ V+ +L+ P Q R Sbjct: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 Query: 56 V----LDVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 V ++ +++++ +++ L N G K W + N+ Sbjct: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 + M KA + + G+I+N+ + + G +A V LTKS+A ++ Sbjct: 134 GTFYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWAC 191 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 GIR NCV PG + + + E + G + ++ R EE++ + +L S Sbjct: 192 SGIRINCVAPGVIYSQTAVENYGSWG--QSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 Query: 228 ESAYVTGNPVIIDGGWSL 245 ++++TG V +DGG SL Sbjct: 250 AASFITGQSVDVDGGRSL 267 >5OVL-A nrPDB Length = 300 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 63/243 (25%), Positives = 111/243 (45%), Gaps = 17/243 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A A +G KV T +L DVT +D Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL------FGVQCDVTDSAAVD 122 Query: 67 QFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + EV ++VL AG ++ E+ ++ +N N+ + + M Sbjct: 123 RAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQR 182 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 ++ G II + SV+ + G+ N+ Y+ KA +IG+ +S++ + + G+ N V PG +DT Sbjct: 183 KRFGRIIFIGSVSG-MWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDT 241 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 R E + L R TAEE+A +LAS++++Y+ G + +DGG Sbjct: 242 EM------TRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGG 295 Query: 243 WSL 245 + Sbjct: 296 MGM 298 >5YSS-A nrPDB Length = 256 Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats. Identities = 80/256 (31%), Positives = 123/256 (48%), Gaps = 17/256 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIAT-----DINESKLQELEKYPGIQTRV 56 L GK ++T + GIG A A+ GA +I D + + + K PG Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGA- 59 Query: 57 LDVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 D++ + QI E +D+L N AG H + W+ + +N+ S++ Sbjct: 60 -DLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHT 118 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + LP M A+ G IIN++SV + + Y K V+GLTK++A + Q I C Sbjct: 119 TRLALPGMRARNWGRIINIASVHG-LVASKEKSAYVAAKHGVVGLTKTIALETAQTEITC 177 Query: 173 NCVCPGTVDTPSLQERIQAR----GNPEEARNDFLK-RQKTGRFATAEEIAMLCVYLASD 227 N +CPG V TP +Q++I R PE AR+ L +Q + F T E++ L ++L SD Sbjct: 178 NALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSD 237 Query: 228 ESAYVTGNPVIIDGGW 243 +A V G +DGGW Sbjct: 238 GAAQVRGVAWNMDGGW 253 >3W8F-A nrPDB Length = 260 Score = 223 bits (568), Expect = 7e-59, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 128/258 (49%), Gaps = 18/258 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTRVL- 57 L GK ++T + GIG A A A+ GA V+ E + LE G++ L Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 58 -DVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 D++ + I + A + LD+L N AG H + + W+ + LN+ +++ Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 A LP M Q G IIN++S A + VN+ Y K V+GLTK A + +GI C Sbjct: 122 TAAALPIMQKQGWGRIINIAS-AHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITC 180 Query: 173 NCVCPGTVDTPSLQERIQARGNPE------EARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 N +CPG V TP ++++I+A + AR ++Q + +F T E++ V+L+S Sbjct: 181 NAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS 240 Query: 227 DESAYVTGNPVIIDGGWS 244 + +TG + +DGGW+ Sbjct: 241 AAADQMTGTTLSLDGGWT 258 >1NFF-A nrPDB Length = 260 Score = 222 bits (567), Expect = 8e-59, Method: Composition-based stats. Identities = 86/247 (34%), Positives = 126/247 (51%), Gaps = 18/247 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV--LDV 59 GRL GKV +++ A+G+G + A EGAKV+ DI + + + + R LDV Sbjct: 3 GRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDV 62 Query: 60 TKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T+ Q +D L VL N AG ++ GT+ D +W +++N+ ++L I+A Sbjct: 63 TQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRA 122 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + M G+IIN+SS+ + G V Y+ TK AV GLTKS A + GIR N + Sbjct: 123 VVKPMKEAGRGSIINISSIEG-LAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSI 181 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG V TP + + + GR A E++ L VYLASDES+Y TG Sbjct: 182 HPGLVKTPMTDWV-----------PEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGA 230 Query: 236 PVIIDGG 242 ++DGG Sbjct: 231 EFVVDGG 237 >2ZAT-A nrPDB Length = 260 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 67/249 (26%), Positives = 123/249 (49%), Gaps = 15/249 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGIQTRVLD 58 L+ KV ++TA+ GIG A A A++GA V+ + + + + + V Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71 Query: 59 VTKKKQ----IDQFANEVERLDVLFNVAGFVHH-GTVLDCEEKDWDFSMNLNVRSMYLMI 113 V K + + N +D+L + A G ++D E+ WD +++NV++ LM Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 KA +P+M + G+++ +SSV + N Y+ +K A++GLTK++A + + IR N Sbjct: 132 KAVVPEMEKRGGGSVLIVSSV-GAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVN 190 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 C+ PG + T Q + E + + R E+ A + +L S++++Y+T Sbjct: 191 CLAPGLIKTNFSQVLWMDKARKEYMKESL----RIRRLGNPEDCAGIVSFLCSEDASYIT 246 Query: 234 GNPVIIDGG 242 G V++ GG Sbjct: 247 GETVVVGGG 255 >1O5I-A nrPDB Length = 249 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 67/239 (28%), Positives = 125/239 (52%), Gaps = 12/239 (5%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 K +++ AA++GIG+A A ++EGA+V NE EL K G + V D+ +K + Sbjct: 19 DKGVLVLAASRGIGRAVADVLSQEGAEVTICARNE----ELLKRSGHRYVVCDL--RKDL 72 Query: 66 DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS 125 D +V+ +D+L AG G + +D+ +++ +M +++ +LP M + Sbjct: 73 DLLFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPAMKEKGW 132 Query: 126 GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSL 185 G I+ ++S S + + N ++ + A+ G K+++ + GI NCV PG +T + Sbjct: 133 GRIVAITSF-SVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWTETERV 191 Query: 186 QERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWS 244 +E + EE + + R A EEIA + +L S++++Y+TG +++DGG S Sbjct: 192 KELLS-----EEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVDGGLS 245 >1X1T-A nrPDB Length = 260 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 81/258 (31%), Positives = 128/258 (49%), Gaps = 18/258 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQTRV-- 56 L GKV ++T + GIG A A A +GA ++ ++ E L G++ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 57 LDVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 D++K + + D ++ R+D+L N AG H + D + WD + LN+ +++ Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHG 121 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 A LP M Q G IIN++S A + N+ Y K V+G TK A + QGI Sbjct: 122 TAAALPHMKKQGFGRIINIAS-AHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITA 180 Query: 173 NCVCPGTVDTPSLQERIQARGNPE------EARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 N +CPG V TP ++++I A AR ++Q + +F T E++ V+LAS Sbjct: 181 NAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLAS 240 Query: 227 DESAYVTGNPVIIDGGWS 244 D +A +TG V +DGGW+ Sbjct: 241 DAAAQITGTTVSVDGGWT 258 >4CQL-A nrPDB Length = 261 Score = 221 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 75/262 (28%), Positives = 128/262 (48%), Gaps = 25/262 (9%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG---------- 51 RL + ++T A GIG+A ++ A EGA V A D++ + QE + G Sbjct: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 Query: 52 --IQTRVLDVTKKKQIDQFANEVERL-----DVLFNVAGFVHHGTVLDCEEKDWDFSMNL 104 DV++ + +V+ V+ + AG +L E DWD + + Sbjct: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 Query: 105 NVRSMYLMIKAFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163 N++ +L+ +A +++ G+IIN+SS+ V G V + Y+ +KA VIGLT++ A Sbjct: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-GNVGQTNYAASKAGVIGLTQTAAR 185 Query: 164 DFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVY 223 + + GIRCN V PG + TP Q+ P++ + + G E++A + + Sbjct: 186 ELGRHGIRCNSVLPGFIATPMTQKV------PQKVVDKITEMIPMGHLGDPEDVADVVAF 239 Query: 224 LASDESAYVTGNPVIIDGGWSL 245 LAS++S Y+TG V + GG + Sbjct: 240 LASEDSGYITGTSVEVTGGLFM 261 >1GEG-A nrPDB Length = 256 Score = 221 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 81/253 (32%), Positives = 119/253 (47%), Gaps = 16/253 (6%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTRV-LDVT 60 KV ++T A QGIG+A AL ++G V D N++ + E+ + G V +DV+ Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVS 61 Query: 61 KKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + Q+ +Q + DV+ N AG + + D N+NV+ + I+A Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAA 121 Query: 117 LPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + + G IIN S A V G VYS++K AV GLT++ A D GI N Sbjct: 122 VEAFKKEGHGGKIINACSQAGHV-GNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 176 CPGTVDTPSLQERIQARGNPE-----EARNDFLKRQKTGRFATAEEIAMLCVYLASDESA 230 CPG V TP E + +F KR GR + E++A YLAS +S Sbjct: 181 CPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSD 240 Query: 231 YVTGNPVIIDGGW 243 Y+TG ++IDGG Sbjct: 241 YMTGQSLLIDGGM 253 >6CI9-A nrPDB Length = 259 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 64/251 (25%), Positives = 113/251 (45%), Gaps = 15/251 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-LEKYPGIQTRV----LD 58 L+G+ I+T ++GIG+ A FA G V+ T N+ L + G + +V D Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRAD 66 Query: 59 VTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 VT + + + + LD++ AG G + D D + + +N + +++ Sbjct: 67 VTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQ 126 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 A L + A G ++ SS+ + G Y +KAA +G ++ A + + I N Sbjct: 127 AALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINA 186 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG + T L E ++ + GR + +I ++ A+DE+AYVTG Sbjct: 187 VLPGNIMTEGLDEM------GQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTG 240 Query: 235 NPVIIDGGWSL 245 +++DGG L Sbjct: 241 QTLVVDGGQVL 251 >5OJG-A nrPDB Length = 260 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 75/251 (29%), Positives = 119/251 (47%), Gaps = 13/251 (5%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE---------LEKYPGIQ 53 R +GKV I+TAA +GIG A A EGA V+ N+ + E L K GI Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 54 TRVLDVTKKKQ-IDQFANEVERLDVLFNVAGFVH-HGTVLDCEEKDWDFSMNLNVRSMYL 111 + +K+ +D + ++++L N G G +L+ ++ WD +NV++ + Sbjct: 67 GHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQ 126 Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 M K P + + G II +S S+ K Y TK ++GLT+++A + IR Sbjct: 127 MTKLVHPHIAKEGGGAIIFNASY-SAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIR 185 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 N + PG + T Q + E+ D + GR ++ A YLASD+S+Y Sbjct: 186 VNGIAPGVIKTKMSQVLWDGGEDAEKELTDI-QEIALGRLGVPDDCAGTVAYLASDDSSY 244 Query: 232 VTGNPVIIDGG 242 +TG +II GG Sbjct: 245 ITGEMIIIAGG 255 >3EZL-A nrPDB Length = 256 Score = 220 bits (561), Expect = 4e-58, Method: Composition-based stats. Identities = 66/252 (26%), Positives = 110/252 (43%), Gaps = 17/252 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIA----TDINESKLQELEKYPGI-----QT 54 + ++ +T GIG + ++G +V+A K E +K G + Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEG 70 Query: 55 RVLDVTKKKQ-IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 V D KQ D+ EV +DVL N AG +DW ++ N+ S++ + Sbjct: 71 NVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVT 130 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 K + M+ + G IIN+SSV KG + YST KA + G T S+A + +G+ N Sbjct: 131 KQVIDGMVERGWGRIINISSVNGQ-KGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVN 189 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG + T ++ + + R + +EI + +LAS+ES + T Sbjct: 190 TVSPGYIGTDMVKAIRP------DVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFST 243 Query: 234 GNPVIIDGGWSL 245 G ++GG + Sbjct: 244 GADFSLNGGLHM 255 >5VT6-A nrPDB Length = 269 Score = 220 bits (561), Expect = 4e-58, Method: Composition-based stats. Identities = 63/251 (25%), Positives = 116/251 (46%), Gaps = 16/251 (6%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES------KLQELEKYPGIQTRVLD 58 +V +T G+G A + G V + + + E + + +D Sbjct: 24 AKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVD 83 Query: 59 VTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V + ++ A + ++DVL N AG T + + DWD M ++ +M+ + K Sbjct: 84 VADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTK 143 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 F+ M+ ++ G I+N+ SV S +G + Y++ KA + G TK++A + ++GI N Sbjct: 144 QFIAGMVERRFGRIVNIGSVNGS-RGAFGQANYASAKAGIHGFTKTLALETAKRGITVNT 202 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG + T ++ Q + L + GR +E+A L +L SD++ +VTG Sbjct: 203 VSPGYLATAMVEAVPQ-----DVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTG 257 Query: 235 NPVIIDGGWSL 245 + I+GG + Sbjct: 258 ADLAINGGMHM 268 >2CDH-G nrPDB Length = 244 Score = 220 bits (561), Expect = 4e-58, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 122/249 (48%), Gaps = 18/249 (7%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQ-TRVLDVTK 61 V+++T A++GIG+A AL+ + G KV+ +K E +E Y G T DV+K Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 62 KKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + ++ +DV+ N AG ++ ++ WD ++LN+ ++L +A Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 M+ ++ G IIN++SV + G + + Y+ KA VIG +K+ A + + I N VCP Sbjct: 123 KIMMKKRKGRIINIASVVGLI-GNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA-SDESAYVTGNP 236 G + + + E+ L GR E +A L +LA S ++Y+TG Sbjct: 182 GFIASDMTAKL------GEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQA 235 Query: 237 VIIDGGWSL 245 IDGG ++ Sbjct: 236 FTIDGGIAI 244 >4Z9Y-A nrPDB Length = 253 Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats. Identities = 74/249 (29%), Positives = 130/249 (52%), Gaps = 15/249 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKK- 62 L GKV ++T G+GQ A+ A+ G ++ +I E K +EK + R L +T Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPK-DTIEKVTALGRRFLSLTADM 66 Query: 63 -------KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + +++ E +D+L N AG + ++ EK+WD MNLN++S++ M + Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQT 126 Query: 116 FLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + + Q G IIN++S+ S +G + Y+ +K+AV+G+T+ +A ++ + GI N Sbjct: 127 VARQFIKQGKGGKIINIASMLS-FQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNA 185 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 + PG + T + Q+ EE + L R GR+ +++ V+LAS S Y+ G Sbjct: 186 IAPGYMATNNTQQLRA----DEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYING 241 Query: 235 NPVIIDGGW 243 + +DGGW Sbjct: 242 YTIAVDGGW 250 >3UVE-A nrPDB Length = 286 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 76/279 (27%), Positives = 125/279 (44%), Gaps = 35/279 (12%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-----------------NESKLQ 44 GR++GKV +T AA+G G++ A+ A+EGA +IA DI E + Sbjct: 7 GRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAE 66 Query: 45 ELEKYPGIQTRVL----DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLD-CEE 95 + G R++ DV K +D ++ RLD++ AG + G LD E Sbjct: 67 TADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSE 126 Query: 96 KDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVI 155 +DW +++N+ ++ +KA +P M+A G I ++S +K + Y K V+ Sbjct: 127 EDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVV 186 Query: 156 GLTKSVAADFIQQGIRCNCVCPGTVDTPSLQER---------IQARGNPEEARNDFLKRQ 206 GL ++ + Q IR N V P V TP L ++ G + A + Sbjct: 187 GLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHT 246 Query: 207 KTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + +I+ ++ ASDE+ Y+TG + ID G L Sbjct: 247 LPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >5OVJ-A nrPDB Length = 256 Score = 218 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 63/243 (25%), Positives = 111/243 (45%), Gaps = 17/243 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A A +G KV T +L DVT +D Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL------FGVQCDVTDSAAVD 78 Query: 67 QFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + EV ++VL AG ++ E+ ++ +N N+ + + M Sbjct: 79 RAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQR 138 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 ++ G II + SV+ + G+ N+ Y+ KA +IG+ +S++ + + G+ N V PG +DT Sbjct: 139 KRFGRIIFIGSVSG-MWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDT 197 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 R E + L R TAEE+A +LAS++++Y+ G + +DGG Sbjct: 198 EM------TRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGG 251 Query: 243 WSL 245 + Sbjct: 252 MGM 254 >3WYE-A nrPDB Length = 256 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 122/252 (48%), Gaps = 14/252 (5%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTRV-LDVT 60 KV ++T A QGIG+A AL ++G V D N++ + E+ + G V +DV+ Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVS 61 Query: 61 KKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + Q+ +Q + DV+ N AG +L+ E+D ++NV S++ I+A Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAA 121 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 + + G I ++ ++++G YSTTK AV GLT++ A D GI N C Sbjct: 122 VEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 177 PGTVDTPSLQERIQARGNPE-----EARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 PG V T ++ E ++ GR + E++A L +LAS +S Y Sbjct: 182 PGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSDY 241 Query: 232 VTGNPVIIDGGW 243 +TG ++IDGG Sbjct: 242 MTGQSLLIDGGM 253 >3VZS-A nrPDB Length = 257 Score = 216 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 68/251 (27%), Positives = 112/251 (44%), Gaps = 17/251 (6%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIA----TDINESKLQELEKYPGI-----QTR 55 ++ +T GIG A A++G +V+A K E +K G + Sbjct: 13 TQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGN 72 Query: 56 VLDVTKKK-QIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V D K D+ +EV +DVL N AG DWD ++ N+ S++ + K Sbjct: 73 VADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTK 132 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 + M + G I+N+SSV KG + YST KA + G T ++A + +G+ N Sbjct: 133 QVIDGMADRGWGRIVNISSVNGQ-KGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT 191 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG + T + + ++ + + R EEIA +C +L+S+ES + TG Sbjct: 192 VSPGYIATDMV------KAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTG 245 Query: 235 NPVIIDGGWSL 245 ++GG + Sbjct: 246 ADFSLNGGLHM 256 >3D3W-A nrPDB Length = 244 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 70/243 (28%), Positives = 121/243 (49%), Gaps = 7/243 (2%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-EKYPGIQTRVLDVTK 61 L G+ +++T A +GIG+ A GA+V+A ++ L L + PGI+ +D+ Sbjct: 4 FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGD 63 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 + ++ V +D+L N A L+ ++ +D S +N+R++ + + ++ Sbjct: 64 WEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLI 123 Query: 122 AQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 A+ G I+N+SS S + V N VY +TK A+ LTK +A + IR N V P V Sbjct: 124 ARGVPGAIVNVSSQCSQ-RAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVV 182 Query: 181 DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIID 240 T Q +P +A+ L R G+FA E + ++L SD S TG+ + ++ Sbjct: 183 MTSMGQ---ATWSDPHKAKT-MLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVE 238 Query: 241 GGW 243 GG+ Sbjct: 239 GGF 241 >5T5Q-A nrPDB Length = 247 Score = 216 bits (550), Expect = 8e-57, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 114/250 (45%), Gaps = 18/250 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG----IQTRVLDV 59 + + ++LT A GIG+A A F GA ++ TD++ L G I T D Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 66 Query: 60 TKKKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + ++ +D L AG + + DW ++++N+ ++ + K Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCKR 126 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 LP + +I+ ++S+A+ VN Y TK A++ +T++++ + + R N V Sbjct: 127 ALPALKEDS--SIVTLASLAAYRGAYVN-AHYGATKGAMVSMTRALSRELAPK-TRVNGV 182 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG ++TP E ++ R ++ + + R EIA + +L S +++VTG Sbjct: 183 SPGIIETPMTSELLKTR------MDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGE 236 Query: 236 PVIIDGGWSL 245 + ++GG + Sbjct: 237 TIQVNGGIYM 246 >6NRP-A nrPDB Length = 263 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 65/248 (26%), Positives = 120/248 (48%), Gaps = 21/248 (8%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYP-GIQTRVLDVT 60 + I++T +++GIG+A AL A+ G V + E +QE++ + DV Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 61 KKKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 +++ + Q + + AG H G ++DWD ++ ++ Y ++K Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPL 144 Query: 117 -LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +P + +K G I+ +SSV+ + G + YS KA +IG TK++A + ++ I NCV Sbjct: 145 IMPMIHLRKGGRIVTLSSVSG-IMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCV 203 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG ++T + +E + LK R +E+A + +L SDE++YVT Sbjct: 204 APGLIETEMVT---------DEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQ 254 Query: 236 PVIIDGGW 243 + ++GG Sbjct: 255 VISVNGGL 262 >4AVY-A nrPDB Length = 242 Score = 212 bits (541), Expect = 8e-56, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 128/239 (53%), Gaps = 9/239 (3%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 G+ +++T + GIG A A+ FA GA+V+A ++ + ++P I+ LD+T ++ Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAP-RHPRIRREELDITDSQR 68 Query: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124 + + + RLDVL N AG + + ++ + LN+ + L + P +LAQ+ Sbjct: 69 LQRLFEALPRLDVLVNNAGISRDR--EEYDLATFERVLRLNLSAAMLASQLARP-LLAQR 125 Query: 125 SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPS 184 G+I+N++S+ S+ G +R YS +K A++ LT+S+A ++ + IR N + PG +DTP Sbjct: 126 GGSILNIASMYSTF-GSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDTPL 184 Query: 185 LQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGW 243 EA ++R R+ A E+A +L +++VTG + +DGG+ Sbjct: 185 GAGLKADV----EATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGGY 239 >1UZM-A nrPDB Length = 247 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 61/243 (25%), Positives = 114/243 (46%), Gaps = 17/243 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 + +++T +GIG A A A +G KV T + G+ +DVT +D Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPK------GLFGVEVDVTDSDAVD 69 Query: 67 QFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + V ++VL + AG ++ E+ ++ +N N+ + + + M Sbjct: 70 RAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQR 129 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 K G +I + SV+ + G+ N+ Y+ +KA VIG+ +S+A + + + N V PG +DT Sbjct: 130 NKFGRMIFIGSVSG-LWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDT 188 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 R E + L+ R T E+A + +LAS++++Y++G + +DGG Sbjct: 189 DM------TRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGG 242 Query: 243 WSL 245 + Sbjct: 243 MGM 245 >3V2H-A nrPDB Length = 281 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 121/255 (47%), Gaps = 18/255 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINE-----SKLQELE--KYPGIQTRVLDV 59 K ++T + GIG A A A+ GA ++ + E+ + D+ Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 85 Query: 60 TKKKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 TK +I A+ D+L N AG + D + WD + +N+ S + I+ Sbjct: 86 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 145 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +P M + G IIN++S A + + Y K ++GLTK+VA + + G+ N + Sbjct: 146 AIPPMKKKGWGRIINIAS-AHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSI 204 Query: 176 CPGTVDTPSLQERIQARGNPEEARND------FLKRQKTGRFATAEEIAMLCVYLASDES 229 CPG V TP ++++I + + LK Q T +F T E++A L +YLA D++ Sbjct: 205 CPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDDA 264 Query: 230 AYVTGNPVIIDGGWS 244 A +TG V +DGGW+ Sbjct: 265 AQITGTHVSMDGGWT 279 >4CQM-B nrPDB Length = 244 Score = 211 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 114/246 (46%), Gaps = 18/246 (7%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG--IQTRVLDVTKKK 63 KV + ++GIG+A A AR+G ++ N + G DV K+ Sbjct: 9 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 68 Query: 64 QIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 + E+ R++ L N AG G ++ + +D ++ N+ L KA + Sbjct: 69 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 128 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 M+ Q+ G+I+N+ S+ +KG + VYS +K ++G ++++A + ++ IR N V PG Sbjct: 129 MIQQQGGSIVNVGSIVG-LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 187 Query: 180 VDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 V T ++ K GRF E+A V+L ES Y+TG+ +++ Sbjct: 188 VHTDMTKDL---------KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 236 Query: 240 DGGWSL 245 DGG L Sbjct: 237 DGGLQL 242 >1AHH-A nrPDB Length = 255 Score = 211 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 124/249 (49%), Gaps = 16/249 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQTRV-L 57 RLDGK I+T A GIG+ A+ FA GA V+ +DIN E+++ G Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 Query: 58 DVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 D+T ++++ A+ ++ ++D+L N AG D D+ + LNV S + + Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 + P+M G I+ ++S+A+ K +N Y+++KAA L +++A D ++ IR N Sbjct: 127 QLVAPEMEKNGGGVILTITSMAAENK-NINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 + PG + T +L+ I E L+ R ++IA ++L S +++V+ Sbjct: 186 GIAPGAILTDALKSVITP-----EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 Query: 234 GNPVIIDGG 242 G + + GG Sbjct: 241 GQILTVSGG 249 >4RZI-B nrPDB Length = 240 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 72/243 (29%), Positives = 114/243 (46%), Gaps = 11/243 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDV-TKK 62 L+ KVI++T +GIG A GAKV TD+ + G+ V D+ + Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT--EALGVVANVTDLESMT 63 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 + +++ + + AG DWD +N+N++ + IK F+ M Sbjct: 64 AAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEGMYE 123 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDT 182 +K+G+I+ +SS++ +G V + YS TKA VIG+ KS+A + + G+R N V PG +DT Sbjct: 124 RKAGSIVAISSISGE-RGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFIDT 182 Query: 183 PSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD-ESAYVTGNPVIIDG 241 E+ R K RF EEIA +L S S+YVTG + ++G Sbjct: 183 EM------TLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVNG 236 Query: 242 GWS 244 Sbjct: 237 AHH 239 >3V2G-A nrPDB Length = 271 Score = 210 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 77/249 (30%), Positives = 120/249 (48%), Gaps = 19/249 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-----LQELEKYPGIQTRV-L 57 L GK +T ++GIG A A A EGA V T +N ++ + E+E+ G + Sbjct: 29 LAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIRA 88 Query: 58 DVTKKKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 D + I+Q + LD+L N AG H + + D+D M +N R+ ++ I Sbjct: 89 DNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFVAI 148 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 ++ + G II + S + + +YS +KAA+ GLTK +A D +GI N Sbjct: 149 RSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGITVN 206 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 V PG+ DT A G+ EA+ + R TG + ++IA L +LA + +VT Sbjct: 207 IVHPGSTDTDMN----PADGDHAEAQRE---RIATGSYGEPQDIAGLVAWLAGPQGKFVT 259 Query: 234 GNPVIIDGG 242 G + IDGG Sbjct: 260 GASLTIDGG 268 >1K2W-A nrPDB Length = 256 Score = 210 bits (535), Expect = 4e-55, Method: Composition-based stats. Identities = 82/253 (32%), Positives = 119/253 (47%), Gaps = 13/253 (5%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG--IQTRVLDV 59 RLDGK ++T +A+GIG+A A A+ REGA+V DIN + G LDV Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDV 60 Query: 60 TKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T + ID+ E +D+L N A +++ + +D +NV M++A Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120 Query: 116 FLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 M+A G IINM+S A +G VY TKAAVI LT+S + I+ GI N Sbjct: 121 VARAMIAGGRGGKIINMASQAGR-RGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNA 179 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQ-----KTGRFATAEEIAMLCVYLASDES 229 + PG VD + E KRQ GR AE++ + ++LA+ E+ Sbjct: 180 IAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEA 239 Query: 230 AYVTGNPVIIDGG 242 Y+ +DGG Sbjct: 240 DYIVAQTYNVDGG 252 >4IS3-A nrPDB Length = 268 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 79/254 (31%), Positives = 119/254 (46%), Gaps = 18/254 (7%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIA-------TDINESKLQELEKYPGIQ 53 M + KV I+T +GIG AAA F GAKV D ++L+EL + Sbjct: 20 MNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVL 79 Query: 54 TRVLDVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSM 109 D+T + + Q A + RLDV+ N AG + E+++ M++NV + Sbjct: 80 GFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGV 139 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + M K G IIN +SV + G ++ Y +KA+VIGLT + + I++ Sbjct: 140 FNGAWCAYQCMKDAKKGVIINTASVTG-IFGSLSGVGYPASKASVIGLTHGLGREIIRKN 198 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 IR V PG V+T GNP E +LK R EEIA + ++LASD + Sbjct: 199 IRVVGVAPGVVNTDM------TNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASDLA 252 Query: 230 AYVTGNPVIIDGGW 243 + +T V +DG + Sbjct: 253 SGITATTVSVDGAY 266 >3OIC-A nrPDB Length = 258 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 62/251 (24%), Positives = 117/251 (46%), Gaps = 15/251 (5%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE-----SKLQELEKYP-GIQTRVLD 58 K ++T +++G+G+AAA+ A G ++ +E+EK + + Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 59 VTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V + +I + + RLDV N A V++ EE WD++MN+N +++ + Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQ 122 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 M G+I+++SS+ S++ + N +KAA+ LT+ +A + + I N Sbjct: 123 EAAKLMEKNGGGHIVSISSL-GSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNA 181 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V G +DT +L+ N E+ D + GR +++ +L S ++ + G Sbjct: 182 VSGGAIDTDALKH----FPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRG 237 Query: 235 NPVIIDGGWSL 245 +I+DGG SL Sbjct: 238 QTIIVDGGRSL 248 >3RWB-A nrPDB Length = 247 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 67/248 (27%), Positives = 114/248 (45%), Gaps = 13/248 (5%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVT 60 RL GK ++T AAQGIG+A A A +GA VI +DIN + G + R + D++ Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADIS 62 Query: 61 KKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + E+ +D+L N A V D + W +++N+ +++ +A Sbjct: 63 DPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRAG 122 Query: 117 LPKMLAQKS-GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +M A G +I+++S + G N Y K VIG T+++A + + I N V Sbjct: 123 TDQMRAAGKAGRVISIAS-NTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAV 181 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG +++ ++ EA Q E IA + +LASD++ ++TG Sbjct: 182 TPGLIESDGVKASP-----HNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARWITGQ 236 Query: 236 PVIIDGGW 243 + +D G Sbjct: 237 TLNVDAGM 244 >4HP8-A nrPDB Length = 247 Score = 206 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 69/244 (28%), Positives = 124/244 (50%), Gaps = 10/244 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN--ESKLQELEKYPGIQTRVL-DVT 60 L+G+ ++T A G+GQA A+ A GA+V+ + L + K G + +L D Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFA 66 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 + D+L N AG + ++ E DWD M++N+++++ +AF ++ Sbjct: 67 DPLAAKDSFTDAG-FDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKEL 125 Query: 121 LAQKS-GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 LA+ G ++N++S+ S +G + Y+ K V GLTK +A ++ +GI N + PG Sbjct: 126 LAKGRSGKVVNIASLLS-FQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGY 184 Query: 180 VDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 ++T + + + L+R GR+ +E+IA V+L+S + YV G + + Sbjct: 185 IETNNTEALRADAARNKA----ILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILNV 240 Query: 240 DGGW 243 DGGW Sbjct: 241 DGGW 244 >4MOW-A nrPDB Length = 256 Score = 206 bits (525), Expect = 6e-54, Method: Composition-based stats. Identities = 74/254 (29%), Positives = 120/254 (47%), Gaps = 16/254 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTR 55 M +L GKV I+T A++GIG A A A A EGA V+ + ++ + + + G Sbjct: 9 MSKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVA 68 Query: 56 V-LDVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 V DV+K +D RLDVL N +G + E+ + + NV + Sbjct: 69 VGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVL 128 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 L +A + + + +IIN+SSV +S+ VYS TK AV +T +A + + I Sbjct: 129 LTTQAAVKHL--GEGASIINISSVVTSIT-PPASAVYSGTKGAVDAITGVLALELGPRKI 185 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESA 230 R N + PG + T + E L + GR +IA + V+LASD++ Sbjct: 186 RVNAINPGMIVTEGTHSAGIIGSDLE---AQVLGQTPLGRLGEPNDIASVAVFLASDDAR 242 Query: 231 YVTGNPVIIDGGWS 244 ++TG +++ GG + Sbjct: 243 WMTGEHLVVSGGLN 256 >4DBZ-A nrPDB Length = 281 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 70/260 (26%), Positives = 112/260 (43%), Gaps = 17/260 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES----KLQELEKYP-GIQTR 55 M D +V ++T A GIG A +EG +V E L+EL + R Sbjct: 21 MATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGR 80 Query: 56 VLDVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV + + +DVL N AG G + ++ W + N+ ++ Sbjct: 81 TCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFR 140 Query: 112 MIKAFLPK--MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + K L ML + +G I+N++S +G+V+ YS +K V+G TK++ + + G Sbjct: 141 VTKQVLKAGGMLERGTGRIVNIASTGGK-QGLVHAAPYSASKHGVVGFTKALGLELARTG 199 Query: 170 IRCNCVCPGTVDTPSLQERIQARGN-----PEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 I N VCPG V+TP + + EEA + R GR+ E+A + YL Sbjct: 200 ITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYL 259 Query: 225 ASDESAYVTGNPVIIDGGWS 244 +A VT + + GG Sbjct: 260 IGPGAAAVTAQALNVCGGLG 279 >3A28-C nrPDB Length = 258 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 76/253 (30%), Positives = 119/253 (47%), Gaps = 16/253 (6%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT-------RVLDV 59 KV ++T AQGIG+ + A +G + D+ + + Q E I+ LDV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 60 TKKK----QIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T K ID+ A ++ DVL N AG +L+ E+D ++NV S++ I+A Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 K I ++ ++++G YSTTK AV GLT++ A + +G N Sbjct: 123 ASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAY 182 Query: 176 CPGTVDTPSLQ----ERIQARGNP-EEARNDFLKRQKTGRFATAEEIAMLCVYLASDESA 230 PG V T + E + G P E ++ GR + E++A L +LAS+ S Sbjct: 183 APGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENSN 242 Query: 231 YVTGNPVIIDGGW 243 YVTG +++DGG Sbjct: 243 YVTGQVMLVDGGM 255 >2CFC-A nrPDB Length = 250 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 83/251 (33%), Positives = 130/251 (51%), Gaps = 18/251 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYP------GIQTRVLDVT 60 +V I+T A+ G G A A F G +V A D++ L+E + + DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 61 KKKQIDQF----ANEVERLDVLFNVAGFVH---HGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + ++ + +DVL N AG G + + +D M +NVR ++L Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 +A LP ML Q +G I+N++SVAS + R Y+T+K AV+ LTKSVA D+ GIRCN Sbjct: 123 RAVLPHMLLQGAGVIVNIASVAS-LVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCN 181 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 VCPG ++TP Q R+ + E R+ L R TA ++A ++LA +++ YV Sbjct: 182 AVCPGMIETPMTQWRL----DQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVN 237 Query: 234 GNPVIIDGGWS 244 G +++DG ++ Sbjct: 238 GAALVMDGAYT 248 >3UF0-A nrPDB Length = 273 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 76/247 (30%), Positives = 128/247 (51%), Gaps = 12/247 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIA---TDINESKLQELEKYPG-IQTRVLDV 59 L G+ ++T A GIG+A A +AR GA V+A TD + E+ G + V D+ Sbjct: 29 LAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVADL 88 Query: 60 TKKKQIDQFANEVE---RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + A E+ R+DVL N AG + + W + +N+ + +++ ++F Sbjct: 89 ADLEGAANVAEELAATRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLSRSF 148 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 MLA SG I+ ++S+ S +G N Y+ +K AV+GLT+++A+++ +G+ N + Sbjct: 149 GTAMLAHGSGRIVTIASMLS-FQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNALA 207 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 PG V T + +E + R GR+AT E++ V+LASD ++YV G Sbjct: 208 PGYVVTANTAALRA----DDERAAEITARIPAGRWATPEDMVGPAVFLASDAASYVHGQV 263 Query: 237 VIIDGGW 243 + +DGGW Sbjct: 264 LAVDGGW 270 >4E6P-A nrPDB Length = 259 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 80/254 (31%), Positives = 119/254 (46%), Gaps = 13/254 (5%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG--IQTRVLD 58 M RL+GK ++T +A+GIG+A A A+ REGA V DI+ + ++ G +D Sbjct: 3 MKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMD 62 Query: 59 VTKKKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 VT++ ID LD+L N A +++ + ++ +NV ++ Sbjct: 63 VTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQ 122 Query: 115 AFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 A +M+AQ G IINM+S A +G +Y TKAAVI LT+S D I+ I N Sbjct: 123 AAARQMIAQGRGGKIINMASQAGR-RGEALVAIYCATKAAVISLTQSAGLDLIKHRINVN 181 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKR-----QKTGRFATAEEIAMLCVYLASDE 228 + PG VD E KR GR TAE++ + ++LAS E Sbjct: 182 AIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAE 241 Query: 229 SAYVTGNPVIIDGG 242 S Y+ +DGG Sbjct: 242 SDYIVSQTYNVDGG 255 >2P91-A nrPDB Length = 285 Score = 203 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 65/259 (25%), Positives = 113/259 (43%), Gaps = 20/259 (7%) Query: 1 MGRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDIN---ESKLQELEKYPGIQTR 55 MG L+GK ++T A + I A +F REGA++ T E +++E+ K G Sbjct: 16 MGLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLV 75 Query: 56 V-LDVTKKKQIDQF----ANEVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNV 106 V DV+ + I LD++ + + G V+D + + +M+++V Sbjct: 76 VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISV 135 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 S+ + + LP M ++G I+ +S + K V + V KAA+ + +A D Sbjct: 136 YSLIALTRELLPLM-EGRNGAIVTLSYYGAE-KVVPHYNVMGIAKAALESTVRYLAYDIA 193 Query: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 + G R N + G V T + E K G+ T E++ V+L S Sbjct: 194 KHGHRINAISAGPVKTLAAYSITGFHLLMEHT----TKVNPFGKPITIEDVGDTAVFLCS 249 Query: 227 DESAYVTGNPVIIDGGWSL 245 D + +TG V +D G+ + Sbjct: 250 DWARAITGEVVHVDNGYHI 268 >4IIV-A nrPDB Length = 267 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 67/248 (27%), Positives = 114/248 (45%), Gaps = 19/248 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATD-INESKLQE-----LEKYPGIQTRVLDVT 60 + +++T A++GIG+A A A +G + + + QE + + DV Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVA 86 Query: 61 KKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 ++Q + + + + AG DWD ++ N+ S Y +I+ Sbjct: 87 NREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQPC 146 Query: 117 LPKML-AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 + M+ A++ G II +SSV+ V G + YS KA +IG TK++A + ++ I NC+ Sbjct: 147 IMPMIGARQGGRIITLSSVSG-VMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCI 205 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG +DT ++ E A + + R AEE+A L YL SD + YVT Sbjct: 206 APGLIDTGMIE-------MEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQ 258 Query: 236 PVIIDGGW 243 + I+GG Sbjct: 259 VISINGGM 266 >3WTC-A nrPDB Length = 262 Score = 202 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 79/255 (30%), Positives = 120/255 (47%), Gaps = 16/255 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL--D 58 L GK+ +T AAQGIG+A AL A++GA VI D+ + L E K G + L D Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTAD 65 Query: 59 VTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 ++ + Q + A + LD++ N AG +LD E + + ++NV+ + ++ Sbjct: 66 ISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLWGMQ 125 Query: 115 AFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 A + G IIN S+A +G YS TK AV LT+S A + GI N Sbjct: 126 AAATLFKEKGTKGKIINACSIAGH-EGYPLLGAYSATKFAVRALTQSAAKELASSGITVN 184 Query: 174 CVCPGTVDTPSLQERIQARGNPE-----EARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 CPG V T + +++ GR TA+++A YL+S + Sbjct: 185 SYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLSSSD 244 Query: 229 SAYVTGNPVIIDGGW 243 + Y+TG V+IDGG Sbjct: 245 ADYMTGQSVLIDGGL 259 >3R3S-A nrPDB Length = 294 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 123/256 (48%), Gaps = 19/256 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-----LQELEKYPGIQTRV 56 GRL + ++T GIG+AAA+A+AREGA V + + ++ L + G + + Sbjct: 45 GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVL 104 Query: 57 L--DVTKKK----QIDQFANEVERLDVLFNVAGFVHHGT-VLDCEEKDWDFSMNLNVRSM 109 L D++ + + + + LD+L VAG + D + + + +NV ++ Sbjct: 105 LPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFAL 164 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + + + +P + K +II SS+ + + + Y+ TKAA++ ++ +A ++G Sbjct: 165 FWITQEAIPLL--PKGASIITTSSIQA-YQPSPHLLDYAATKAAILNYSRGLAKQVAEKG 221 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 IR N V PG + T + G ++ F ++ R E+A + VYLAS ES Sbjct: 222 IRVNIVAPGPIWTAL----QISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQES 277 Query: 230 AYVTGNPVIIDGGWSL 245 +YVT + GG L Sbjct: 278 SYVTAEVHGVCGGEHL 293 >1DOH-A nrPDB Length = 283 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 65/259 (25%), Positives = 110/259 (42%), Gaps = 19/259 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPG-IQTRVL 57 L+GKV ++T A +GIG+ A+ R G KVI N E + ++K Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKA 86 Query: 58 DVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 +V + I + E +LD++ + +G V G V D +++D +N R + + Sbjct: 87 NVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVA 146 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 + + + G +I M S+ K V VYS +K A+ + +A D + I N Sbjct: 147 REAYKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITVN 204 Query: 174 CVCPGTVDTPSLQERIQAR-------GNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 V PG + T + N E ++ R +IA + +LAS Sbjct: 205 VVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLAS 264 Query: 227 DESAYVTGNPVIIDGGWSL 245 ++ +VTG + IDGG + Sbjct: 265 NDGGWVTGKVIGIDGGACM 283 >1CYD-A nrPDB Length = 244 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 71/242 (29%), Positives = 121/242 (50%), Gaps = 7/242 (2%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY-PGIQTRVLDVTKK 62 G ++T A +GIG+ A GAKV+A S L L K PGI+ +D+ Sbjct: 5 FSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDW 64 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 ++ + +D+L N A V L+ ++ +D S ++N+RS++ + + M+ Sbjct: 65 DATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMIN 124 Query: 123 QK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVD 181 + G+I+N+SS+ + V N YS+TK A+ LTK++A + IR N V P V Sbjct: 125 RGVPGSIVNVSSMVAHVT-FPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVL 183 Query: 182 TPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDG 241 T ++ +PE AR +R +FA E++ ++L SD SA +G +++D Sbjct: 184 TDMGKKV---SADPEFARK-LKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDA 239 Query: 242 GW 243 G+ Sbjct: 240 GY 241 >3T7C-A nrPDB Length = 299 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 69/272 (25%), Positives = 125/272 (45%), Gaps = 31/272 (11%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDI-------------NESKLQELEK 48 G+++GKV +T AA+G G++ A+ AREGA +IA D+ + + + + Sbjct: 24 GKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQ 83 Query: 49 YPGIQTRV----LDVTK----KKQIDQFANEVERLDVLFNVAGFVHHGT-VLDCEEKDWD 99 + R+ +DV + +D ++ RLD++ A GT + + K W Sbjct: 84 VEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWR 143 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159 +++N+ ++ + +P ++A K G I +S ++G N Y +K + GL + Sbjct: 144 DMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMR 203 Query: 160 SVAADFIQQGIRCNCVCPGTVDTPSLQERIQAR------GNPEEARNDFLKRQK---TGR 210 ++A + + IR N VCP +V TP L R NP RQ Sbjct: 204 TMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIP 263 Query: 211 FATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + +I+ ++L SD++ Y+TG + +DGG Sbjct: 264 YVEPADISNAILFLVSDDARYITGVSLPVDGG 295 >5EJ2-A nrPDB Length = 308 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 73/272 (26%), Positives = 120/272 (44%), Gaps = 31/272 (11%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE---------SKLQELEKYPG- 51 GR+ GKV ++ AA+G G++ A+ A+EGA +IA DI S ++L + Sbjct: 33 GRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADL 92 Query: 52 -------IQTRVLDVTK----KKQIDQFANEVERLDVLFNVAGFVHHGT-VLDCEEKDWD 99 I T +DV K +D ++ RLD++ AG G + + W Sbjct: 93 VKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQ 152 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159 +++N+ ++ +KA +P +L+ G I ++S K N Y K VIGL + Sbjct: 153 DMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMR 212 Query: 160 SVAADFIQQGIRCNCVCPGTVDTPSLQE---------RIQARGNPEEARNDFLKRQKTGR 210 + A + IR N V P V T + ++ G + A + Sbjct: 213 AFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP 272 Query: 211 FATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 + A +I+ ++LASDES YVTG + +D G Sbjct: 273 WVDASDISNAVLFLASDESRYVTGVSLPVDAG 304 >2FWM-X nrPDB Length = 250 Score = 200 bits (510), Expect = 3e-52, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 122/250 (48%), Gaps = 14/250 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 GK + +T A +GIG A ALAF GAKV T +++ QE T V+DV Sbjct: 5 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQE---QYPFATEVMDVADAA 59 Query: 64 QIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 Q+ Q E ERLD L N AG + G ++DW + +NV + + + + + Sbjct: 60 QVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 119 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 Q+ G I+ ++S A+ + Y +KAA+ L SV + G+RCN V PG+ Sbjct: 120 FRRQRGGAIVTVASDAAHTP-RIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGS 178 Query: 180 VDTPSLQERIQARGNPEEARNDFLKR----QKTGRFATAEEIAMLCVYLASDESAYVTGN 235 DT + + E+ F ++ G+ A +EIA ++LASD ++++T Sbjct: 179 TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQ 238 Query: 236 PVIIDGGWSL 245 +++DGG +L Sbjct: 239 DIVVDGGSTL 248 >1HXH-A nrPDB Length = 253 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 79/255 (30%), Positives = 127/255 (49%), Gaps = 14/255 (5%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DV 59 RL GKV ++T A G+G EGAKV +DINE+ Q+L G ++ + DV Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDV 61 Query: 60 TKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + + + L+VL N AG + G + +D+ + +N S+++ + Sbjct: 62 SSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQ 121 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG--IRCN 173 + M G+IINM+SV+S + + YS +KAAV LT++ A +QG IR N Sbjct: 122 GIAAMKET-GGSIINMASVSSWLP-IEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVN 179 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 + P + TP +Q + + E +D K + GR E IA L ++LASDES+ ++ Sbjct: 180 SIHPDGIYTPMMQASLPKGVSKEMVLHDP-KLNRAGRAYMPERIAQLVLFLASDESSVMS 238 Query: 234 GNPVIIDG---GWSL 245 G+ + D G L Sbjct: 239 GSELHADNSILGMGL 253 >2B4Q-A nrPDB Length = 276 Score = 199 bits (507), Expect = 9e-52, Method: Composition-based stats. Identities = 68/254 (26%), Positives = 109/254 (42%), Gaps = 16/254 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES----KLQELEKYPGIQTRVLDV 59 L G++ ++T ++GIGQ A GA+V + L Y Q D+ Sbjct: 27 LAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADL 86 Query: 60 TKKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + + + A + RLD+L N AG + W+ M LNV S++ I+ Sbjct: 87 SSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQQ 146 Query: 116 FLPKML----AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 LP + A+ +IN+ SVA Y +KAA+ L++ +A + + + I Sbjct: 147 LLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVGEHIN 206 Query: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 N + PG + + N +A GR+ EE+A L + LA AY Sbjct: 207 VNVIAPGRFPSRMTRHI----ANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAGAY 262 Query: 232 VTGNPVIIDGGWSL 245 +TGN + IDGG+ L Sbjct: 263 MTGNVIPIDGGFHL 276 >3U5T-A nrPDB Length = 267 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 62/248 (25%), Positives = 108/248 (43%), Gaps = 18/248 (7%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQ-TRVLD 58 KV I+T A++GIG A A A +G V+ ++ E +E G T D Sbjct: 26 TNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQAD 85 Query: 59 VTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 V+ + + +DVL N AG + T+ + + +D + +N++ + ++ Sbjct: 86 VSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNTLR 145 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 ++ + G IINMS+ + + +Y+ KA V +T ++ + + I N Sbjct: 146 EAAQRL--RVGGRIINMSTSQVGLLH-PSYGIYAAAKAGVEAMTHVLSKELRGRDITVNA 202 Query: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 V PG T E G +E R+ F K R T ++IA +LA + A+V G Sbjct: 203 VAPGPTATDLFLE-----GKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNG 257 Query: 235 NPVIIDGG 242 + +GG Sbjct: 258 QVLRANGG 265 >3GDF-A nrPDB Length = 267 Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats. Identities = 65/255 (25%), Positives = 118/255 (46%), Gaps = 21/255 (8%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDIN-----ESKLQELEKYPGIQTRV 56 L GKV+++T A+ +G+G AA A GA V T + E ++ELEK GI+ + Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKA 77 Query: 57 --LDV----TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 V + +K + + ++D AG +LD + W+ + +++ + Sbjct: 78 YKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNGTF 137 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVN-RCVYSTTKAAVIGLTKSVAADFIQQG 169 KA + +G+++ +S++ + + Y+ KA I + +S+A ++ + Sbjct: 138 HCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW-RDF 196 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 R N + PG +DT P+E + + GR A+E+ VY ASD S Sbjct: 197 ARVNSISPGYIDTGLSDFV------PKETQQLWHSMIPMGRDGLAKELKGAYVYFASDAS 250 Query: 230 AYVTGNPVIIDGGWS 244 Y TG ++IDGG++ Sbjct: 251 TYTTGADLLIDGGYT 265 >2HSD-A nrPDB Length = 253 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 72/247 (29%), Positives = 111/247 (44%), Gaps = 13/247 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV--LDVTK 61 L GK +I+T A+G+G AA GA+V+ D+ + + + G R LDVT Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTI 62 Query: 62 KKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 ++ + E +D L N AG + + + + +N+ +++ +K + Sbjct: 63 EEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVI 122 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 P M G+I+N+SS A+ + G+ Y +K V GL+K A + IR N V P Sbjct: 123 PAMKDAGGGSIVNISS-AAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHP 181 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPV 237 G TP E +G GR EIA V L SD S+YVTG + Sbjct: 182 GMTYTPMTAETGIRQGEGNY------PNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGAEL 235 Query: 238 IIDGGWS 244 +DGGW+ Sbjct: 236 AVDGGWT 242 >5JS6-A nrPDB Length = 274 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 68/229 (29%), Positives = 109/229 (47%), Gaps = 9/229 (3%) Query: 23 ALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQIDQFANE----VERLDV 77 AF GA+V+ D +ES + LE + PG + DVT++ + +E RLD Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDC 87 Query: 78 LFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136 + N AG + + + + LN+ Y + K LP + + GN+IN+SS+ Sbjct: 88 VVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-GNVINISSLVG 146 Query: 137 SVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPE 196 ++ G Y TK AV +TK++A D G+R NC+ PG + TP +E +P Sbjct: 147 AI-GQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPR 205 Query: 197 EARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + Q GR E+ V+LAS E+ + TG +++ GG L Sbjct: 206 ATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 253 >3UN1-A nrPDB Length = 260 Score = 196 bits (499), Expect = 7e-51, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 117/249 (46%), Gaps = 20/249 (8%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 M R KV+++T A+QGIG A+ +V+AT + P I T D++ Sbjct: 23 MMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKP----SADPDIHTVAGDIS 78 Query: 61 KKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 K + D+ E R+D L N AG ++ ++D+D ++ +NV + + + Sbjct: 79 KPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRA 138 Query: 117 LPKMLAQKSGNIINM-SSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +ML Q SG+I+++ +S+ + + S TK + +T+S+A +F + G+R N V Sbjct: 139 AAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNAV 198 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGN 235 PG + TP +P E + GR ++ +YL + + ++TG Sbjct: 199 SPGVIKTPM---------HPAETHSTLAGLHPVGRMGEIRDVVDAVLYL--EHAGFITGE 247 Query: 236 PVIIDGGWS 244 + +DGG + Sbjct: 248 ILHVDGGQN 256 >5B1Y-A nrPDB Length = 270 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 70/246 (28%), Positives = 115/246 (46%), Gaps = 16/246 (6%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY-------PGIQTRVLDVTK 61 ++T ++GIG+A L FAREG V+ + + L E P T +DV Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGD 85 Query: 62 KKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + + ++ V L+VL N AG + G + + +W+ ++ +N+ +YL+ K L Sbjct: 86 PDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTKLLL 145 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 P + K +I+N++S+A VV YS +KA VIGLTK +A GIR N V P Sbjct: 146 PLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAP 205 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD-ESAYVTGNP 236 V+T + + + E R E++A ++LA S +TG+ Sbjct: 206 SFVETDMTRSFL----DTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITGHV 261 Query: 237 VIIDGG 242 + I+ G Sbjct: 262 LSINAG 267 >4FC7-A nrPDB Length = 277 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 62/250 (24%), Positives = 101/250 (40%), Gaps = 14/250 (5%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKYPGIQTRVL---- 57 L KV +T GIG A F R G + + L K G R Sbjct: 24 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 83 Query: 58 -DVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 DV +DQ E R+D+L N A + M+++ + + Sbjct: 84 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 143 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 + K G I+N+++ + +G + + KAAV +T+ +A ++ Q IR Sbjct: 144 SRVLYEKFFRDHGGVIVNITATLGN-RGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 202 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N + PG + S E ++ G P+ + + + R EIA +YLAS ++YV Sbjct: 203 NSLAPGPI---SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 259 Query: 233 TGNPVIIDGG 242 TG ++ DGG Sbjct: 260 TGAVLVADGG 269 >3U4C-A nrPDB Length = 281 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 62/257 (24%), Positives = 105/257 (40%), Gaps = 17/257 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQTRV 56 + + + A+QGIG+A AL A + ++ N ++ L K+P V Sbjct: 19 SHMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIV 78 Query: 57 L--DVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 L D++ + + ++ RLDVL N T +C +D + + Sbjct: 79 LAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYI 138 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 IK M + G IIN+ G N S AA+I +K+++ I Sbjct: 139 DAIKRASSLMKQNEFGRIINIVGNLWKEPG-ANMFTNSMMNAALINASKNISIQLAPHNI 197 Query: 171 RCNCVCPGTVDTPSLQERI-----QARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 NC+ PG + T + + + + ++A R +AEE A L +LA Sbjct: 198 TVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLA 257 Query: 226 SDESAYVTGNPVIIDGG 242 S+E++Y+TG + DGG Sbjct: 258 SEEASYITGQQISADGG 274 >4TRR-A nrPDB Length = 269 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 73/261 (27%), Positives = 121/261 (46%), Gaps = 17/261 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQ-TR 55 M L+GK ++T AA GIG+ AL A+ GA V D+N+ E+ K G Sbjct: 9 MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGV 68 Query: 56 VLDVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 +DVT ++ + D+ A +D+L + AG + + DW ++V +L Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFL 128 Query: 112 MIKAFLPKMLA-QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 KA L M + G +I M SV S + + Y T K ++GL + +A + + + Sbjct: 129 TTKAALKHMYKDDRGGVVIYMGSVHSH-EASPLKSAYVTAKHGLLGLARVLAKEGAKHNV 187 Query: 171 RCNCVCPGTVDTPSLQERIQARG------NPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 R + VCPG V TP + ++I + E + L G F T +++A ++L Sbjct: 188 RSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFL 247 Query: 225 ASDESAYVTGNPVIIDGGWSL 245 ++ SA +TG I+ GW + Sbjct: 248 SAFPSAALTGQSFIVSHGWFM 268 >3V8B-A nrPDB Length = 283 Score = 187 bits (476), Expect = 3e-48, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 119/252 (47%), Gaps = 14/252 (5%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY---PGIQTRVL--DVTKK 62 V ++T A GIG+A ALA A +G V A ++++E+ G Q L DV+ + Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 63 KQIDQFAN----EVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 Q+ + LD++ AG + D + +WD ++ +N+R +L + + Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTV 149 Query: 118 PKMLAQKSGNIINMSSVASSVK-GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 P + + G I+ +SS+ + Y+ TKAA + + + +A + + IR N VC Sbjct: 150 PYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNAVC 209 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKT---GRFATAEEIAMLCVYLASDESAYVT 233 PG ++T ++ K Q G+ +E++A L +L S+ + +VT Sbjct: 210 PGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARHVT 269 Query: 234 GNPVIIDGGWSL 245 G+PV IDGG L Sbjct: 270 GSPVWIDGGQGL 281 >4EGF-A nrPDB Length = 266 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 75/253 (29%), Positives = 124/253 (49%), Gaps = 14/253 (5%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG------IQTRV 56 RLDGK ++T A +GIG A AFA GA+++ + + S+L + G + T Sbjct: 17 RLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVA 76 Query: 57 LDVTKKKQ----IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +D+ + + A LDVL N AG H V+D + + +D ++ +N+R+ L+ Sbjct: 77 IDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALL 136 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 A M+A G I + A+++ + + Y T+KA ++ TK +A + GIR Sbjct: 137 ASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRA 196 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 N VCP V T Q E + R GRFA E++ V+LASD ++ + Sbjct: 197 NSVCPTVVLTEMGQRVWG----DEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMI 252 Query: 233 TGNPVIIDGGWSL 245 G + +DGG+++ Sbjct: 253 NGVDIPVDGGYTM 265 >2BGM-A nrPDB Length = 278 Score = 185 bits (470), Expect = 1e-47, Method: Composition-based stats. Identities = 73/232 (31%), Positives = 113/232 (48%), Gaps = 11/232 (4%) Query: 23 ALAFAREGAKVIATDINESKLQELEKYPG----IQTRVLDVTKKKQIDQFANEV----ER 74 A F R GAKV+ DI + Q++ G I DVTK + + + + Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 75 LDVLFNVAGFVHHGT--VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMS 132 LD++F G + +L+ +D+ M++NV +L+ K M+ K G+I+ + Sbjct: 93 LDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTA 152 Query: 133 SVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQAR 192 S++S G VY+ TK AV+GLT S+ + + GIR NCV P V +P L + Sbjct: 153 SISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGVD 212 Query: 193 GNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWS 244 + E K G AE++A YLA DES YV+G ++IDGG++ Sbjct: 213 SSRVEELAHQAANLK-GTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYT 263 >5O3Z-A nrPDB Length = 263 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 59/257 (22%), Positives = 105/257 (40%), Gaps = 19/257 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK-------YPGIQTRVLDV 59 +V ++ Q +G A+ G V D+NES L +D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 60 TKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 T + ++ A R D+L AG + D+D S+ +N+ +L + Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSRE 126 Query: 116 FLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 F M+ G II ++S + V G + YS K +GLT+S+A D + GI + Sbjct: 127 FSKLMIRDGIKGRIIQINSKSGKV-GSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHS 185 Query: 175 VCPG-TVDTPSLQERIQARGN-----PEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 + G + +P Q + PEE ++ + R +++ + ++ ASD+ Sbjct: 186 LMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDK 245 Query: 229 SAYVTGNPVIIDGGWSL 245 +AY TG + + GG + Sbjct: 246 AAYCTGQSINVTGGQVM 262 >4M89-A nrPDB Length = 261 Score = 184 bits (468), Expect = 3e-47, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 112/260 (43%), Gaps = 21/260 (8%) Query: 1 MGRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQ----T 54 MG L GK I++T + + I A A +GA++ T + + + + K Sbjct: 1 MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELV 60 Query: 55 RVLDVTKKKQIDQFANEVER----LDVLFNVAGFVHH----GTVLD-CEEKDWDFSMNLN 105 DV +I+Q ++ + LD L + GF G LD + ++ + ++ Sbjct: 61 FRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEIS 120 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S+ + KA P M+ ++ I+ +S + +V+ + N V KA++ + AA Sbjct: 121 AYSLPALAKAARP-MMRGRNSAIVALSYL-GAVRAIPNYNVMGMAKASLEAGIRFTAACL 178 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 ++GIRCN + G + T + + + R T EE+ +L Sbjct: 179 GKEGIRCNGISAGPIKTLAAS----GIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLL 234 Query: 226 SDESAYVTGNPVIIDGGWSL 245 SD S+ +TG +DGG+S+ Sbjct: 235 SDLSSGITGEITYVDGGYSI 254 >3OIG-A nrPDB Length = 266 Score = 182 bits (463), Expect = 9e-47, Method: Composition-based stats. Identities = 57/258 (22%), Positives = 107/258 (41%), Gaps = 23/258 (8%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR------ 55 L+G+ I++ A + I A + GA++I T E + + + G R Sbjct: 5 LEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIIL 64 Query: 56 VLDVTKKKQIDQFA----NEVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVR 107 DVT +I+ +V + + + F + G L+ + + N++ Sbjct: 65 PCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSY 124 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 S+ ++KA P M G+I+ ++ + + + N V KA++ K +AAD + Sbjct: 125 SLTAVVKAARPMMTE--GGSIVTLTYLGGEL-VMPNYNVMGVAKASLDASVKYLAADLGK 181 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 + IR N + G + T S + + D +R R T EE+ +L SD Sbjct: 182 ENIRVNSISAGPIRTLSAK----GISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSD 237 Query: 228 ESAYVTGNPVIIDGGWSL 245 S +TG + +D G+ + Sbjct: 238 MSRGITGENLHVDSGFHI 255 >1H5Q-A nrPDB Length = 265 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 70/254 (27%), Positives = 113/254 (44%), Gaps = 23/254 (9%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV------LDV 59 K II+T +GIG A A A GA V + + E+ + G + V DV Sbjct: 14 NKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDV 73 Query: 60 TKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + K I Q ++ + L AG + +D+ F ++NV ++ +A Sbjct: 74 SNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRA 133 Query: 116 FLPK-MLAQKSGNIINMSSVA------SSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 + Q+ G+I+ SS++ SS+ G + + Y+++KAA L K +AA++ Sbjct: 134 VAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEWASA 193 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 GIR N + PG V+T Q ++ R+ RFA EE+ + L SD Sbjct: 194 GIRVNALSPGYVNTD------QTAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDH 247 Query: 229 SAYVTGNPVIIDGG 242 + Y+TG IDGG Sbjct: 248 ATYMTGGEYFIDGG 261 >4ZJU-A nrPDB Length = 275 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 107/258 (41%), Gaps = 21/258 (8%) Query: 2 GRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINES---KLQELEKYPGIQ-TR 55 G L GK ++ A I A A REGA++ T NE ++ E + G + Sbjct: 12 GLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVF 71 Query: 56 VLDVTKKKQIDQFANE----VERLDVLFNVAGFVH----HGTVLDCEEKD-WDFSMNLNV 106 DV +ID E + +D + + GF G D ++D + + +++ Sbjct: 72 PCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISA 131 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 S M +A P +L + G ++ ++ S + + N V KA++ + +A+ Sbjct: 132 YSFVAMARAAKP-LLQARQGCLLTLTYQGSE-RVMPNYNVMGMAKASLEAGVRYLASSLG 189 Query: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 GIR N + G + T + R + + K R T EE+ ++L S Sbjct: 190 VDGIRVNAISAGPIRTLAASGIKSFR----KMLDANEKVAPLKRNVTIEEVGNAALFLCS 245 Query: 227 DESAYVTGNPVIIDGGWS 244 ++ +TG + +D G++ Sbjct: 246 PWASGITGEILYVDAGFN 263 >5CFZ-A nrPDB Length = 305 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 57/260 (21%), Positives = 102/260 (39%), Gaps = 22/260 (8%) Query: 1 MGRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINES---KLQELEKYPGIQTR 55 MG L GK I++T A I A A REGA++ T N+ +++E G Sbjct: 44 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 103 Query: 56 -VLDVTKKKQIDQFANEVERL----DVLFNVAGFVHHGTVL-----DCEEKDWDFSMNLN 105 DV + ID E+ ++ D + GF + + + + +++ Sbjct: 104 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 163 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S M KA + G+ + S + + + N V KA++ + +A Sbjct: 164 SYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 220 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 +G+R N + G + T + + + R T E++ +L Sbjct: 221 GPEGVRVNAISAGPIRTLAAS----GIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 276 Query: 226 SDESAYVTGNPVIIDGGWSL 245 SD SA ++G V +DGG+S+ Sbjct: 277 SDLSAGISGEVVHVDGGFSI 296 >5JY1-A nrPDB Length = 274 Score = 181 bits (460), Expect = 3e-46, Method: Composition-based stats. Identities = 70/256 (27%), Positives = 118/256 (46%), Gaps = 16/256 (6%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQTRV 56 MG L+ +V ++T A GIG+ A +F EGA VI +INES QE+ + G V Sbjct: 9 MGLLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFV 68 Query: 57 -LDVTKKKQIDQ----FANEVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMY 110 DVT K I+ + LD+L N A + + + ++ + ++ ++ + + Sbjct: 69 KTDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATW 128 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 ++A M ++ G I+N S+ + G Y+T KA ++GLT+S A+++ + I Sbjct: 129 WAMRAAFVPMRERRWGRIVNFYSIDTET-GAWLHGDYNTAKAGIVGLTRSAASEWGRFNI 187 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAE-EIAMLCVYLASDES 229 N + P T + E + GR E +I V+ AS+ S Sbjct: 188 TVNAIAP----TAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEMS 243 Query: 230 AYVTGNPVIIDGGWSL 245 +VTG + +DGG L Sbjct: 244 RFVTGETLHVDGGLHL 259 >4JQC-A nrPDB Length = 282 Score = 180 bits (456), Expect = 6e-46, Method: Composition-based stats. Identities = 57/260 (21%), Positives = 102/260 (39%), Gaps = 22/260 (8%) Query: 1 MGRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINES---KLQELEKYPGIQTR 55 MG L GK I++T A I A A REGA++ T N+ +++E G Sbjct: 21 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 80 Query: 56 -VLDVTKKKQIDQFANEVERL----DVLFNVAGFVHHGTVL-----DCEEKDWDFSMNLN 105 DV + ID E+ ++ D + GF + + + + +++ Sbjct: 81 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 140 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S M KA + G+ + S + + + N V KA++ + +A Sbjct: 141 SYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 197 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 +G+R N + G + T + + + R T E++ +L Sbjct: 198 GPEGVRVNAISAGPIRTLAAS----GIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 253 Query: 226 SDESAYVTGNPVIIDGGWSL 245 SD SA ++G V +DGG+S+ Sbjct: 254 SDLSAGISGEVVHVDGGFSI 273 >5TF4-A nrPDB Length = 274 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 63/258 (24%), Positives = 103/258 (39%), Gaps = 21/258 (8%) Query: 2 GRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKLQELE----KYPGIQTR 55 G L GK ++ + I A + GA++ T E+ + +E + G Sbjct: 8 GLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCG 67 Query: 56 VLDVTKKKQIDQFAN----EVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVR 107 DV+ ID N + +LD L + GF G +D E ++ +MN++V Sbjct: 68 HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVY 127 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 S+ + K M G+I+ ++ + K V N V KAA+ K +A D Sbjct: 128 SLTALTKRAEKLM--SDGGSILTLTYYGAE-KVVPNYNVMGVAKAALEASVKYLAVDLGP 184 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 + IR N + G + T + G+ R T EE+ +YL SD Sbjct: 185 KHIRVNAISAGPIKTLAAS----GIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSD 240 Query: 228 ESAYVTGNPVIIDGGWSL 245 S VTG +D G+++ Sbjct: 241 LSRSVTGEVHHVDSGYNI 258 >4NR0-A nrPDB Length = 273 Score = 178 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 55/261 (21%), Positives = 109/261 (41%), Gaps = 23/261 (8%) Query: 1 MGRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINES---KLQELEKYPGIQ-- 53 MG L GK ++ A I A A REGA++ T N+ +++E G + Sbjct: 1 MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPE 60 Query: 54 -TRVLDVTKKKQIDQFANEVER----LDVLFNVAGFVH----HGTVLDCE-EKDWDFSMN 103 DV QI+ + + LD++ + GF G + + + + Sbjct: 61 LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHD 120 Query: 104 LNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163 ++ S + KA +M+ ++G+++ +S + + + + N V KA++ + +A Sbjct: 121 ISAYSFIALAKAG-REMMKGRNGSLLTLSYLGAE-RTMPNYNVMGMAKASLEAGVRYLAG 178 Query: 164 DFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVY 223 +G R N V G + T + R + ++ R T EE+ + Sbjct: 179 SLGAEGTRVNAVSAGPIRTLAASGIKSFR----KMLAANERQTPLRRNVTIEEVGNAGAF 234 Query: 224 LASDESAYVTGNPVIIDGGWS 244 L SD ++ ++G + +DGG++ Sbjct: 235 LCSDLASGISGEILYVDGGFN 255 >3PXX-A nrPDB Length = 287 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 71/285 (24%), Positives = 110/285 (38%), Gaps = 44/285 (15%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN----------------ESKLQ 44 MGR+ KV+++T A+G G++ A+ A EGA +I DI E Sbjct: 5 MGRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGL 64 Query: 45 ELEKYPGIQ-TRVLDVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD 99 E+EK T +DV + + E +LDV+ AG G L + + Sbjct: 65 EVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLPV--QAFA 122 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSV----------KGVVNRCVYST 149 + +++ + + A LP + + +II SVA + YS Sbjct: 123 DAFDVDFVGVINTVHAALPYLTS--GASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSY 180 Query: 150 TKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQER---------IQARGNPEEARN 200 K V T +AA Q IR N + P V+T L ++A + Sbjct: 181 AKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLA 240 Query: 201 DFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + A +I+ +LASDES YVTG +D G L Sbjct: 241 FPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >4CR6-A nrPDB Length = 271 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 109/254 (42%), Gaps = 16/254 (6%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL---- 57 GRL GK I+T AA GIG+A A+ REGA V+A D+ + PG Sbjct: 11 GRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGAIPIACDLAD 70 Query: 58 DVTKKKQIDQFANEVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + + LD+L G LD + DWD +++N+ +L +A Sbjct: 71 RAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAG 130 Query: 117 LPKMLAQKSG------NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 M+A +G II + SV S Y K V LT+++A D + GI Sbjct: 131 ARAMVAAGAGKDGRSARIITIGSVNS-FMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGI 189 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESA 230 N + PG VD E+ ++ GR EE+A V+LA D S+ Sbjct: 190 LVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVA----LGRPGLPEEVATAAVFLAEDGSS 245 Query: 231 YVTGNPVIIDGGWS 244 ++TG+ + IDGG S Sbjct: 246 FITGSTITIDGGLS 259 >5YCX-A nrPDB Length = 266 Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats. Identities = 60/261 (22%), Positives = 106/261 (40%), Gaps = 23/261 (8%) Query: 1 MGRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELEKYP----GIQT 54 M L GK ++ A + I A + GAK+I T E + + + G ++ Sbjct: 3 MELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQES 62 Query: 55 RV--LDVTKKKQIDQFAN----EVERLDVLFNVAGFVH----HGTVLDCEEKDWDFSMNL 104 V DVT +++ EV + + + F + G +D + + N+ Sbjct: 63 LVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNI 122 Query: 105 NVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 + S+ + + M GNI+ ++ + + V N V KA++ K +A D Sbjct: 123 SAFSLTAVAREAKKVMTE--GGNILTLTYLGGE-RVVKNYNVMGVAKASLEASVKYLAND 179 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 Q GIR N + G + T S + G+ + +R R T EE+ V+L Sbjct: 180 LGQHGIRVNAISAGPIRTLSAKGV----GDFNSILREIEERAPLRRTTTQEEVGDTAVFL 235 Query: 225 ASDESAYVTGNPVIIDGGWSL 245 SD + VTG + +D G+ + Sbjct: 236 FSDLARGVTGENIHVDSGYHI 256 >2YW9-A nrPDB Length = 261 Score = 177 bits (450), Expect = 4e-45, Method: Composition-based stats. Identities = 57/256 (22%), Positives = 105/256 (41%), Gaps = 21/256 (8%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELEKY----PGIQTRVL 57 L GK ++ + +G A A GA+V + E E EK G Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLFRA 65 Query: 58 DVTKKKQIDQFA----NEVERLDVLFNVAGFVH----HGTVLDCEEKDWDFSMNLNVRSM 109 DVT+ +++D LD L + F G +D +DW ++ ++ S+ Sbjct: 66 DVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYSL 125 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + + P + ++ G I+ ++ AS K V V + KAA+ + +A + +G Sbjct: 126 VAVARRAEPLL--REGGGIVTLTYYASE-KVVPKYNVMAIAKAALEASVRYLAYELGPKG 182 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 +R N + G V T + + + + + R T EE+ L ++L S + Sbjct: 183 VRVNAISAGPVRTVAARSIPGFT----KMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLA 238 Query: 230 AYVTGNPVIIDGGWSL 245 + +TG V +D G+ + Sbjct: 239 SGITGEVVYVDAGYHI 254 >3ZV3-A nrPDB Length = 281 Score = 176 bits (447), Expect = 7e-45, Method: Composition-based stats. Identities = 67/260 (25%), Positives = 112/260 (43%), Gaps = 19/260 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT--RVLDV 59 +L G+V ++T A G+G+A F EGA+V D + +L+ELE G V DV Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDV 60 Query: 60 TK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKD-----WDFSMNLNVRSMY 110 K+ ++ ++D L AG + T L +D +D ++NV+ Sbjct: 61 RSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYI 120 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 +KA LP +++ + + +S + +Y+ TK AV+GL + +A + + Sbjct: 121 HAVKACLPALVSSRGSVVFTIS--NAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH-V 177 Query: 171 RCNCVCPGTVDTPS---LQERIQARGNPEEARNDFLKRQ-KTGRFATAEEIAMLCVYLAS 226 R N V PG ++T + + D LK GR EE V+ A+ Sbjct: 178 RVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFAT 237 Query: 227 -DESAYVTGNPVIIDGGWSL 245 +S TG + DGG + Sbjct: 238 RGDSLPATGALLNYDGGMGV 257 >4RGB-A nrPDB Length = 294 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 63/271 (23%), Positives = 107/271 (39%), Gaps = 28/271 (10%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES---------KLQELEKYPG 51 MG LDG+V+ +T AA+G G++ A+ A +GA ++ DI E +ELE+ Sbjct: 20 MGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETAR 79 Query: 52 I--------QTRVLDVTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWD 99 + R DV K + + + +D + AG V + Sbjct: 80 LVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALR 139 Query: 100 FSMNLNVRSMYLMIKAFLPKMLAQK-SGNIINMSSVASSV---KGVVNRCVYSTTKAAVI 155 +++ + ++ + +P M + GN+I SS+ + + G Y T+K A+ Sbjct: 140 LGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAIT 199 Query: 156 GLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEAR---NDFLKRQKTGRFA 212 GL +S A IR N V P TP + E EE N Sbjct: 200 GLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMI 259 Query: 213 TAEEIAMLCVYLASDESAYVTGNPVIIDGGW 243 +++ ++L SD TG+ + +D G Sbjct: 260 EPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >1BDB-A nrPDB Length = 277 Score = 174 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 113/260 (43%), Gaps = 19/260 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG--IQTRVLDV 59 +L G+ +++T A G+G+A F EGAKV D + +L ELE G + V DV Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDV 60 Query: 60 TKKKQIDQFA----NEVERLDVLFNVAGFVHHGT-VLDCEEK----DWDFSMNLNVRSMY 110 + Q A ++D L AG + T ++D E+ +D ++NV+ Sbjct: 61 RSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYI 120 Query: 111 LMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 +KA LP ++A + I +S + +Y+ K A++GL + +A + + Sbjct: 121 HAVKACLPALVASRGNVIFTIS--NAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-V 177 Query: 171 RCNCVCPGTVDTPS---LQERIQARGNPEEARNDFLKRQ-KTGRFATAEEIAMLCVYLAS 226 R N V G +++ + ++ D LK GR EE V+ A+ Sbjct: 178 RVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFAT 237 Query: 227 -DESAYVTGNPVIIDGGWSL 245 ++A TG + DGG + Sbjct: 238 RGDAAPATGALLNYDGGLGV 257 >5KOI-A nrPDB Length = 293 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 56/259 (21%), Positives = 100/259 (38%), Gaps = 22/259 (8%) Query: 2 GRLDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTR 55 G + GK ++ A + A A +GA++ T ++ + + E+ Sbjct: 24 GLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVL 83 Query: 56 VLDVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTV-----LDCEEKDWDFSMNLNV 106 DV +D E LD L + GF + +++ +M ++ Sbjct: 84 PCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISA 143 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 S + + M G+I+ ++ S + + N V KAA+ + + +AAD+ Sbjct: 144 YSFTEVAQRAEKLMK--DGGSILTLTY-GGSTRTIPNYNVMGVAKAALEAMVRYLAADYG 200 Query: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 QGIR N + G V T + AR R R +++ VYL S Sbjct: 201 PQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRR----NSPLRRTVDIDDVGKSAVYLLS 256 Query: 227 DESAYVTGNPVIIDGGWSL 245 D S+ VTG +D G+++ Sbjct: 257 DLSSGVTGEIHFVDSGYNI 275 >2X9N-A nrPDB Length = 288 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 63/276 (22%), Positives = 115/276 (41%), Gaps = 41/276 (14%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL-----QELEKYPGIQTRV 56 ++ ++T AA+ IG+A A+ + G +V+ N ++ EL K V Sbjct: 19 SHMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVV 78 Query: 57 L--DVTK--------KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD------- 99 D+T ++ I+ R DVL N A + ++ + +D Sbjct: 79 CQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVET 138 Query: 100 ---FSMNLNVRSMYLMIKAFLPKMLAQKSG------NIINMSSVASSVKGVVNRCVYSTT 150 + N + +L+ +F + +I+N+ + +Y+ Sbjct: 139 QVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMA-FSLYNMG 197 Query: 151 KAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGR 210 K A++GLT+S A + GIR N V PG + EE ++ + ++ GR Sbjct: 198 KHALVGLTQSAALELAPYGIRVNGVAPGV--------SLLPVAMGEEEKDKWRRKVPLGR 249 Query: 211 F-ATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 A+AE+IA ++L S + Y+TG+ + +DGG SL Sbjct: 250 REASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >4GKB-A nrPDB Length = 258 Score = 173 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 74/250 (29%), Positives = 112/250 (44%), Gaps = 12/250 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL------ 57 L KV+I+T A GIG A ++ A E A + + L+ Q R Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVEL 64 Query: 58 --DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 D + + Q RLD L N AG + G LD + S+ N+ Y M Sbjct: 65 QDDAQCRDAVAQTIATFGRLDGLVNNAGV-NDGIGLDAGRDAFVASLERNLIHYYAMAHY 123 Query: 116 FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCV 175 +P + A + G I+N+SS ++V G N Y +K A + LT+ A + G+R N V Sbjct: 124 CVPHLKATR-GAIVNISS-KTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAV 181 Query: 176 CPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG-RFATAEEIAMLCVYLASDESAYVTG 234 P V TP + I +PE + + G RF T +EIA V+L S +++ TG Sbjct: 182 IPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTG 241 Query: 235 NPVIIDGGWS 244 + +DGG++ Sbjct: 242 EWLFVDGGYT 251 >5I9N-A nrPDB Length = 276 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 56/259 (21%), Positives = 105/259 (40%), Gaps = 22/259 (8%) Query: 1 MGRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQT 54 MG LDGK I+LT + + I A A REGA++ T + + + ++ Sbjct: 1 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELV 60 Query: 55 RVLDVTKKKQIDQFAN----EVERLDVLFNVAGFVHH----GTVLD-CEEKDWDFSMNLN 105 DV QID + LD L + GF G LD +++ + +++ Sbjct: 61 FPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDIS 120 Query: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 S + KA LP + +++ +S + + + + N KAA+ + +A Sbjct: 121 AYSFPALAKAALPMLSDD--ASLLTLSYLGAE-RAIPNYNTMGLAKAALEASVRYLAVSL 177 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 +G+R N + G + T + + + + R T E++ +L Sbjct: 178 GAKGVRVNAISAGPIKTLAAS----GIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLL 233 Query: 226 SDESAYVTGNPVIIDGGWS 244 SD ++ VT + +D G++ Sbjct: 234 SDLASGVTAEVMHVDSGFN 252 >3GRK-A nrPDB Length = 293 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 98/258 (37%), Gaps = 21/258 (8%) Query: 2 GRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELE----KYPGIQTR 55 G L GK ++ A + I A A GA++ T ++ + +E + Sbjct: 27 GLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAG 86 Query: 56 VLDVTKKKQIDQFAN----EVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVR 107 DV ID + +LD L + GF G +D E ++ +M ++V Sbjct: 87 HCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVY 146 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 S+ + + M G+I+ ++ + K + N V KAA+ K +A D Sbjct: 147 SLTAVSRRAEKLM--ADGGSILTLTYYGAE-KVMPNYNVMGVAKAALEASVKYLAVDLGP 203 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 Q IR N + G + T + G+ R T +E+ + +Y SD Sbjct: 204 QNIRVNAISAGPIKTLAAS----GIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSD 259 Query: 228 ESAYVTGNPVIIDGGWSL 245 S VTG D G+ + Sbjct: 260 LSRSVTGEVHHADSGYHV 277 >2O23-A nrPDB Length = 265 Score = 170 bits (431), Expect = 5e-43, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 105/257 (40%), Gaps = 28/257 (10%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--VLDVTK 61 + G V ++T A G+G A A +GA + D+ S + K G DVT Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 69 Query: 62 KKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDC------EEKDWDFSMNLNVRSMYL 111 +K + + R+DV N AG + +D+ +++N+ + Sbjct: 70 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 129 Query: 112 MIKAFLPKM------LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 +I+ +M + G IIN +SVA+ +G V + YS +K ++G+T +A D Sbjct: 130 VIRLVAGEMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPIARDL 188 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK-TGRFATAEEIAMLCVYL 224 GIR + PG TP L PE+ N + R E A L Sbjct: 189 APIGIRVMTIAPGLFGTPLLTSL------PEKVCNFLASQVPFPSRLGDPAEYAHLVQ-- 240 Query: 225 ASDESAYVTGNPVIIDG 241 A E+ ++ G + +DG Sbjct: 241 AIIENPFLNGEVIRLDG 257 >4ALL-A nrPDB Length = 277 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 55/260 (21%), Positives = 102/260 (39%), Gaps = 23/260 (8%) Query: 1 MGRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELEKY------PGI 52 M L+ K ++ A + I A + GAK++ T E +ELEK P Sbjct: 22 MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA 81 Query: 53 QTRVLDVTKKKQI----DQFANEVERLDVLFNVAGFVH----HGTVLDCEEKDWDFSMNL 104 +DV +++ +Q +V +D +++ F + G + + + + ++ Sbjct: 82 HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI 141 Query: 105 NVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 + S+ ++ M + G+I+ + + V N V KA++ K +A D Sbjct: 142 SSYSLTIVAHEAKKLM--PEGGSIVATTYLGGEF-AVQNYNVMGVAKASLEANVKYLALD 198 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 IR N + G + T S + G + +R R E+ YL Sbjct: 199 LGPDNIRVNAISAGPIRTLSAKGV----GGFNTILKEIEERAPLKRNVDQVEVGKTAAYL 254 Query: 225 ASDESAYVTGNPVIIDGGWS 244 SD S+ VTG + +D G+ Sbjct: 255 LSDLSSGVTGENIHVDSGFH 274 >3OML-A nrPDB Length = 613 Score = 168 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 62/249 (24%), Positives = 105/249 (42%), Gaps = 36/249 (14%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-------------LQELEKY 49 R DG+V ++T A G+G+ AL FA GAKV+ D+ + + E+ K Sbjct: 16 RYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 50 PGIQTRVLD--VTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 G + + K I+ R+D+L N AG + +++ E+DW+ +++++ Sbjct: 76 GGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLK 135 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 + +A P M Q G II M+S S + G + Y+ K +IGL +VA + + Sbjct: 136 GSFKCTQAAFPYMKKQNYGRII-MTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL--- 224 + CN + P A E D L + + IA + YL Sbjct: 195 NNVLCNVIVP-----------TAASRMTEGILPDILFNE-----LKPKLIAPVVAYLCHE 238 Query: 225 -ASDESAYV 232 D +Y+ Sbjct: 239 SCEDNGSYI 247 >3K2E-A nrPDB Length = 296 Score = 166 bits (422), Expect = 5e-42, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 103/258 (39%), Gaps = 21/258 (8%) Query: 2 GRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINE---SKLQELEKYPGIQ-TR 55 ++GK ++ A + + A A +GA+V T ++E ++ L + G++ T Sbjct: 26 MLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVKLTV 85 Query: 56 VLDVTKKKQIDQ----FANEVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNVR 107 DV+ + +D A E LD + + F G +D ++ SM+++ Sbjct: 86 PCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCY 145 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 S + P M G+I+ +S + K V + V KAA+ K +A D + Sbjct: 146 SFTYIASKAEPLMT--NGGSILTLSYYGAE-KVVPHYNVMGVCKAALEASVKYLAVDLGK 202 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 Q IR N + G V T + + R T +++ +YL SD Sbjct: 203 QQIRVNAISAGPVRTLASS----GISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSD 258 Query: 228 ESAYVTGNPVIIDGGWSL 245 TG V +D G+ + Sbjct: 259 LGRGTTGETVHVDCGYHV 276 >3RKU-A nrPDB Length = 287 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 117/250 (46%), Gaps = 22/250 (8%) Query: 3 RLDGKVIILTAAAQGIGQAAALAF--AREG-AKVIATDINESKLQELEKY-------PGI 52 RL K +++T A+ GIG+A AL + A G K+I KL+EL+K + Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 53 QTRVLDVTKKKQI----DQFANEVERLDVLFNVAG-FVHHGTVLDCEEKDWDFSMNLNVR 107 LD+T+ ++I + E + +D+L N AG + V +D + NV Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 ++ + +A LP A+ SG+I+N+ S+A +Y +K AV T S+ + I Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGR-DAYPTGSIYCASKFAVGAFTDSLRKELIN 208 Query: 168 QGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD 227 IR + PG V+T ++ RGN E+A+N + A+++A L VY S Sbjct: 209 TKIRVILIAPGLVETEF--SLVRYRGNEEQAKNVYKDTTPL----MADDVADLIVYATSR 262 Query: 228 ESAYVTGNPV 237 + V + + Sbjct: 263 KQNTVIADTL 272 >4J3F-A nrPDB Length = 280 Score = 165 bits (419), Expect = 1e-41, Method: Composition-based stats. Identities = 46/258 (17%), Positives = 101/258 (39%), Gaps = 20/258 (7%) Query: 1 MGRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINE--SKLQELEKYPG-IQTR 55 MG L GK I++T + + I A A REGA++ T + + ++++L Sbjct: 21 MGFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEFNPAAVL 80 Query: 56 VLDVTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLD-----CEEKDWDFSMNLNV 106 DV ++I E+ + LD + + F + + + + +++ Sbjct: 81 PCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDISA 140 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 S + K M+ ++ +++ ++ + + K + + KA++ + A Sbjct: 141 YSFAALAKEG-RSMMKNRNASMVALTYIGAE-KAMPSYNTMGVAKASLEATVRYTALALG 198 Query: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 + GI+ N V G + T + N ++ + + E+ +L S Sbjct: 199 EDGIKVNAVSAGPIKTLAAS----GISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAFLCS 254 Query: 227 DESAYVTGNPVIIDGGWS 244 D + +TG V +D G+ Sbjct: 255 DMATGITGEVVHVDAGYH 272 >1E3W-A nrPDB Length = 261 Score = 164 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 63/257 (24%), Positives = 106/257 (41%), Gaps = 28/257 (10%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT--RVLDVTK 61 + G V ++T A G+G + A +GA + D+ S+ + K G +VT Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 Query: 62 KKQIDQFA----NEVERLDVLFNVAGFV------HHGTVLDCEEKDWDFSMNLNVRSMYL 111 +K++ + R+DV N AG H +D+ +N+N+ + Sbjct: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 Query: 112 MIKAFLPKM------LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 +I+ M + G IIN +SVA+ +G V + YS +K ++G+T +A D Sbjct: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPIARDL 186 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK-TGRFATAEEIAMLCVYL 224 GIR + PG TP L P+ RN + R E A L + Sbjct: 187 APIGIRVVTIAPGLFATPLLTTL------PDTVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 Query: 225 ASDESAYVTGNPVIIDG 241 E+ ++ G + +DG Sbjct: 241 I--ENPFLNGEVIRLDG 255 >5IZ4-A nrPDB Length = 271 Score = 163 bits (412), Expect = 8e-41, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 119/257 (46%), Gaps = 23/257 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINE------SKLQELEKYPGIQTRVL---- 57 V ++T +A GIG A AL FA+ G V + ++ S ++ L + G QT + Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 58 --DVTKKKQIDQFANEVERLDVLFNVAG---FVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 D + +D A+ +R+D L N AG + H ++ +++ +N+ +Y M Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 113 IKAFLPKML----AQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 +A +P + A +S +++N+SS+A + G + Y+ +K AV LT S+A + Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLAG-LNGTGSSIAYAASKGAVNTLTLSLARNLAPH 194 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDE 228 IR N + PG VD L + A + + + R + EIA L +L + Sbjct: 195 -IRVNALAPGMVDDGLLLRVLDAAA-YDGVLSRMTESAPLKRVSRPAEIAELAWFL-TAH 251 Query: 229 SAYVTGNPVIIDGGWSL 245 + +TG + + G L Sbjct: 252 APAITGQVIAAENGLLL 268 >2GDZ-A nrPDB Length = 267 Score = 163 bits (412), Expect = 9e-41, Method: Composition-based stats. Identities = 76/258 (29%), Positives = 122/258 (47%), Gaps = 30/258 (11%) Query: 1 MGRL-DGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-------ESKLQELEKYPGI 52 M + +GKV ++T AAQGIG+A A A +GAKV D N ++ L E + Sbjct: 1 MAHMVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKT 60 Query: 53 QTRVLDVTKKKQI----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRS 108 DV ++Q+ + + RLD+L N AG + EK+W+ ++ +N+ S Sbjct: 61 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVS 112 Query: 109 MYLMIKAFLPKMLAQK---SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS--VAA 163 + L M Q G IINMSS+A + V + VY +K ++G T+S +AA Sbjct: 113 VISGTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQPVYCASKHGIVGFTRSAALAA 171 Query: 164 DFIQQGIRCNCVCPGTVDTPSLQ--ERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLC 221 + + G+R N +CPG V+T L+ E+ + G E ++ K IA Sbjct: 172 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 231 Query: 222 VYLASDESAYVTGNPVII 239 + L D++ + G + I Sbjct: 232 ITLIEDDA--LNGAIMKI 247 >4DA9-A nrPDB Length = 280 Score = 159 bits (404), Expect = 8e-40, Method: Composition-based stats. Identities = 65/253 (25%), Positives = 109/253 (43%), Gaps = 21/253 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE--LEKYPGIQTRVL----DVTK 61 V I+T +GIG A A A G + T I +++ + + G+ RV+ D+ Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 62 ----KKQIDQFANEVERLDVLFNVAGFVH--HGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + +D E R+D L N AG LD + +++D + +N+R +A Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQA 150 Query: 116 FLPKMLA---QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 L MLA + S +IIN++SV S+V R Y +KA + ++ +A + GI Sbjct: 151 VLKAMLASDARASRSIINITSV-SAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAV 209 Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 V PG + + G + L R+ E+I + LA + + Sbjct: 210 FEVRPGIIRSDMTA---AVSGKYDGLIESGL--VPMRRWGEPEDIGNIVAGLAGGQFGFA 264 Query: 233 TGNPVIIDGGWSL 245 TG+ + DGG S+ Sbjct: 265 TGSVIQADGGLSI 277 >1W73-A nrPDB Length = 302 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 48/252 (19%), Positives = 99/252 (39%), Gaps = 15/252 (5%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK------YPGIQTR 55 GKV +T G+G+ + GA+ + L+ + + Sbjct: 22 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAI 81 Query: 56 VLDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 DV + +E+ +++ N A W ++ + Sbjct: 82 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 141 Query: 112 MIKAFLPKMLAQKSGN-IINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGI 170 + +++ + G ++++++ + G ++ KA V ++KS+AA++ + G+ Sbjct: 142 VTLEIGKQLIKAQKGAAFLSITTIYAET-GSGFVVPSASAKAGVEAMSKSLAAEWGKYGM 200 Query: 171 RCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESA 230 R N + PG + T R+ G E + + R GR T EE+A L +L SD ++ Sbjct: 201 RFNVIQPGPIKTKGAFSRLDPTGTFE---KEMIGRIPCGRLGTVEELANLAAFLCSDYAS 257 Query: 231 YVTGNPVIIDGG 242 ++ G + DGG Sbjct: 258 WINGAVIKFDGG 269 >2NWQ-A nrPDB Length = 272 Score = 153 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 56/226 (24%), Positives = 92/226 (40%), Gaps = 17/226 (7%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL----DVTKKK 63 + +T A G G+A A FA G ++ T E +LQ L +TRVL DV + Sbjct: 23 TLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRA 82 Query: 64 Q----IDQFANEVERLDVLFNVAGFV-HHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 +D E L L N AG C+ DWD ++ N++ + + LP Sbjct: 83 AMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLLP 142 Query: 119 KMLAQKSG-NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177 +++A +G +I+N+ SVA VY TKA V + ++ D G+R + P Sbjct: 143 RLIAHGAGASIVNLGSVAGKWP-YPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEP 201 Query: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVY 223 G ++ ++ G+ + E+IA + Sbjct: 202 GLCESEF--SLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFW 241 >1A27-A nrPDB Length = 289 Score = 153 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 57/206 (27%), Positives = 94/206 (45%), Gaps = 17/206 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREG---AKVIATDINE-------SKLQELEKYPG-IQTRV 56 V+++T + GIG A+ A + KV AT + + L PG ++T Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 57 LDVTKKKQIDQFANEV--ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 LDV K + V R+DVL AG G + E +++NV M++ Sbjct: 64 LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 123 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 AFLP M + SG ++ SV + G+ VY +K A+ GL +S+A + G+ + Sbjct: 124 AFLPDMKRRGSGRVLVTGSV-GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 182 Query: 175 VCPGTVDTPSLQERIQARGNPEEARN 200 + G V T +++ + G+PEE + Sbjct: 183 IECGPVHTAFMEKVL---GSPEEVLD 205 >1P33-A nrPDB Length = 289 Score = 153 bits (388), Expect = 6e-38, Method: Composition-based stats. Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 58/287 (20%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATD-INESKLQELEKYPGIQ------TRVLDVT 60 V ++T AA+ +G + A A EG V + + L + T D++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 61 KKKQ---------------------IDQFANEVERLDVLFNVAGFVHHGTVLD------C 93 +D R DVL N A + +L Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 94 EEKDWDFSMNL--------NVRSMYLMIKAFLPKM---LAQKSG---NIINMSSVASSVK 139 S+ + N + Y +IKAF ++ A++ G +I+NM +S + Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTS-Q 187 Query: 140 GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEAR 199 ++ +Y+ K A+ GLT+S A + IR N V PG + P + Sbjct: 188 PLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL--------SVLPDDMPFSVQ 239 Query: 200 NDFLKRQKT-GRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 D+ ++ R ++AEE++ + ++L S ++ Y+TG + +DGG+SL Sbjct: 240 EDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >6CGE-A nrPDB Length = 328 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 57/206 (27%), Positives = 94/206 (45%), Gaps = 17/206 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREG---AKVIATDINE-------SKLQELEKYPG-IQTRV 56 V+++T + GIG A+ A + KV AT + + L PG ++T Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 57 LDVTKKKQIDQFANEV--ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 LDV K + V R+DVL AG G + E +++NV M++ Sbjct: 65 LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 AFLP M + SG ++ SV + G+ VY +K A+ GL +S+A + G+ + Sbjct: 125 AFLPDMKRRGSGRVLVTGSV-GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Query: 175 VCPGTVDTPSLQERIQARGNPEEARN 200 + G V T +++ + G+PEE + Sbjct: 184 IECGPVHTAFMEKVL---GSPEEVLD 206 >4NK4-A nrPDB Length = 301 Score = 150 bits (380), Expect = 4e-37, Method: Composition-based stats. Identities = 54/263 (20%), Positives = 96/263 (36%), Gaps = 25/263 (9%) Query: 1 MGR----LDGKVIILTAAAQ--GIGQAAALAFAREGAKVIATDINESKLQELEKYP---- 50 MGR L GK ++ A I A GA++ + ES + L+ Sbjct: 32 MGRMINILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVD 91 Query: 51 GIQTRVLDVTKKKQIDQFANE----VERLDVLFNVAGFVHH----GTVLDCEEKDWDFSM 102 +V +D E LD + + F G + ++ +M Sbjct: 92 SDFMIPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTM 151 Query: 103 NLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA 162 ++ S +++ M G +I ++ S++ V N + K+A+ TK +A Sbjct: 152 LVSCFSFTEIVRRAAQLM--PHGGAMITLTY-GGSMRVVPNYNAMAPAKSALESSTKYLA 208 Query: 163 ADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCV 222 D+ IR N + G V T + + N + + R + E+I + Sbjct: 209 CDYGGMNIRINAISAGPVRTLAG----ASISNGRDIAAWSKENSPLKRTVSLEDIGNSAL 264 Query: 223 YLASDESAYVTGNPVIIDGGWSL 245 YL S S VTG +D G+++ Sbjct: 265 YLLSYLSNGVTGEIHYVDCGYNI 287 >2PD3-A nrPDB Length = 275 Score = 150 bits (380), Expect = 5e-37, Method: Composition-based stats. Identities = 53/259 (20%), Positives = 103/259 (39%), Gaps = 21/259 (8%) Query: 1 MGRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELE----KYPGIQT 54 MG L GK ++ A + I A + +GA + T +NES + + + Sbjct: 1 MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYV 60 Query: 55 RVLDVTKKKQIDQFAN----EVERLDVLFNVAGFVHH----GTVLDCEEKDWDFSMNLNV 106 LDV+K++ N ++ LD + + F G++L+ + ++ +M ++V Sbjct: 61 YELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISV 120 Query: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 S+ + P + +G + S S K + + V KAA+ + +A D Sbjct: 121 YSLIELTNTLKPLL---NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLG 177 Query: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 + IR N + G + T + + + + EE+ +YL S Sbjct: 178 KHHIRVNALSAGPIRTLASS----GIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLS 233 Query: 227 DESAYVTGNPVIIDGGWSL 245 S+ V+G +D G+ + Sbjct: 234 SLSSGVSGEVHFVDAGYHV 252 >2QHX-A nrPDB Length = 328 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 62/287 (21%), Positives = 110/287 (38%), Gaps = 58/287 (20%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATD-INESKLQELEKYPGIQ------TRVLDVT 60 V ++T AA+ +G++ A EG V + ++ L + T D++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 61 K---------------------KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKD-- 97 + + R DVL N A + +L +E Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 98 ----WDFSMNL--------NVRSMYLMIKAFLPKML---AQKSG---NIINMSSVASSVK 139 +M N + Y +IKAF ++ A+ G +IINM ++ + Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTN-Q 226 Query: 140 GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEAR 199 ++ +Y+ K A+ GLT+S A + IR N V PG + P Sbjct: 227 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--------SVLVDDMPPAVW 278 Query: 200 NDFLKRQKT-GRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + R ++A E++ + ++L S ++ Y+TG V +DGG+SL Sbjct: 279 EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2BFA-A nrPDB Length = 288 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 62/287 (21%), Positives = 110/287 (38%), Gaps = 58/287 (20%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATD-INESKLQELEKYPGIQ------TRVLDVT 60 V ++T AA+ +G++ A EG V + ++ L + T D++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 61 K---------------------KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKD-- 97 + + R DVL N A + +L +E Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 98 ----WDFSMNL--------NVRSMYLMIKAFLPKML---AQKSG---NIINMSSVASSVK 139 +M N + Y +IKAF ++ A+ G +IINM ++ + Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTN-Q 186 Query: 140 GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEAR 199 ++ +Y+ K A+ GLT+S A + IR N V PG + P Sbjct: 187 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--------SVLVDDMPPAVW 238 Query: 200 NDFLKRQKT-GRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + R ++A E++ + ++L S ++ Y+TG V +DGG+SL Sbjct: 239 EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >3E9N-A nrPDB Length = 245 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 53/224 (23%), Positives = 96/224 (42%), Gaps = 18/224 (8%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD----V 59 L K+ ++T A G+G +R+ V A N L L + G++ D V Sbjct: 3 LKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEGVEPIESDIVKEV 61 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 ++ +D+ N ++ +D L + A T+ +W ++LNV + + LP Sbjct: 62 LEEGGVDKLKN-LDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLPA 120 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 + A SG +I ++S A + +Y+ +K A+ GL + + GIR + V PG Sbjct: 121 LRAA-SGCVIYINSGAGNGPH-PGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGP 178 Query: 180 VDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVY 223 +TP LQ + ++G R + + +EIA + Sbjct: 179 TNTPMLQGLMDSQGT--NFRPEI--------YIEPKEIANAIRF 212 >3PPI-A nrPDB Length = 281 Score = 139 bits (352), Expect = 9e-34, Method: Composition-based stats. Identities = 60/257 (23%), Positives = 106/257 (41%), Gaps = 27/257 (10%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVT 60 + +G I++ A G+G+A +G V+ D+ K + L G + + +VT Sbjct: 27 QFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVT 86 Query: 61 KKKQI---DQFANEVERLDVLFNVAG---FVHHGTVLDCEEKD---WDFSMNLNVRSMYL 111 + + + AN++ RL G D D + +++L + Y Sbjct: 87 SEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNGTYN 146 Query: 112 MIK------AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 + + A + G ++ +S+A +G + + Y+ KA VIGLT + A D Sbjct: 147 VARLVAASIAAAEPRENGERGALVLTASIAG-YEGQIGQTAYAAAKAGVIGLTIAAARDL 205 Query: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK-TGRFATAEEIAMLCVYL 224 GIR N + PGT+ TP ++ EEA F R T +E A +L Sbjct: 206 SSAGIRVNTIAPGTMKTPIMESV------GEEALAKFAANIPFPKRLGTPDEFADAAAFL 259 Query: 225 ASDESAYVTGNPVIIDG 241 + + Y+ G + +DG Sbjct: 260 LT--NGYINGEVMRLDG 274 >4DRY-A nrPDB Length = 281 Score = 137 bits (346), Expect = 4e-33, Method: Composition-based stats. Identities = 61/238 (25%), Positives = 91/238 (38%), Gaps = 21/238 (8%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG------IQTR 55 G +G++ ++T G+G+ A A + EG V+ T L G ++ Sbjct: 29 GSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAV 88 Query: 56 VLDVTKKKQIDQFA----NEVERLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMY 110 V DV Q+ E RLD+L N AG V + + + W+ + N+ + Sbjct: 89 VCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAF 148 Query: 111 LMIKAFLPKMLAQ--KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 L + M AQ + G IIN S+++ N Y+ TK A+ GLTKS A D Sbjct: 149 LCTQHAFRMMKAQTPRGGRIINNGSISAQTP-RPNSAPYTATKHAITGLTKSTALDGRMH 207 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLAS 226 I C + G T R+ E IA VY+AS Sbjct: 208 DIACGQIDIGNAATDM-TARMSTGVLQANGEVAAEPTIP------IEHIAEAVVYMAS 258 >5PGZ-A nrPDB Length = 276 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 50/210 (23%), Positives = 90/210 (42%), Gaps = 14/210 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL---------EKYPGIQT 54 L GK +I+T A++GIG+ A ++ GA V+ T +E LQ++ I Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 55 RVLDVTKKKQ-IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + D+T +Q I + + LD+L ++ + M +N S +M Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMS 135 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 A LP ML Q +G+I +SS+A + YS +K A+ G ++ + + + Sbjct: 136 TAALP-MLKQSNGSIAVISSLAGKMT-QPMIAPYSASKFALDGFFSTIRTELYITKVNVS 193 Query: 174 CVCP--GTVDTPSLQERIQARGNPEEARND 201 G +DT + + I N + + + Sbjct: 194 ITLCVLGLIDTETAMKEISGIINAQASPKE 223 >3DWF-A nrPDB Length = 276 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 50/193 (25%), Positives = 89/193 (46%), Gaps = 14/193 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL---------EKYPGIQT 54 L GK +I+T A++GIG+ A A+ GA V+ T ++ LQ++ I Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 55 RVLDVTKKKQ-IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + D+T ++ + + N + LD+L + T E + SM +N S ++ Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLS 128 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 A +P ML Q G+I +SSVA + YS +K A+ G ++ ++F+ + + Sbjct: 129 VAAMP-MLMQSQGSIAVVSSVAGKIT-YPLIAPYSASKFALDGFFSTLRSEFLVNKVNVS 186 Query: 174 CVCP--GTVDTPS 184 G +DT + Sbjct: 187 ITLCILGLIDTET 199 >2DKN-A nrPDB Length = 255 Score = 133 bits (336), Expect = 6e-32, Method: Composition-based stats. Identities = 55/262 (20%), Positives = 98/262 (37%), Gaps = 44/262 (16%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-LEKYPGIQTRVLDVTKKKQID 66 VI +T +A GIG A AR G VI D ++ ++ L G +T V V + Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGRETAVAAVLDRCG-- 60 Query: 67 QFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSG 126 LD L AG + + +N + ++ + + Sbjct: 61 ------GVLDGLVCCAGVG-------VTAANSGLVVAVNYFGVSALLDGLAEALSRGQQP 107 Query: 127 NIINMSSVASSVKGVVNRC-------------------------VYSTTKAAVIGLTKSV 161 + + S+A++ G Y+ +K AV L + Sbjct: 108 AAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVTCLARRN 167 Query: 162 AADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLC 221 D+ +G+R N V PG V+TP LQ ++ +P + GR + E+A Sbjct: 168 VVDWAGRGVRLNVVAPGAVETPLLQ---ASKADPRYGESTRRFVAPLGRGSEPREVAEAI 224 Query: 222 VYLASDESAYVTGNPVIIDGGW 243 +L +++++ G+ + +DGG Sbjct: 225 AFLLGPQASFIHGSVLFVDGGM 246 >1FJH-A nrPDB Length = 257 Score = 133 bits (335), Expect = 8e-32, Method: Composition-based stats. Identities = 60/263 (22%), Positives = 104/263 (39%), Gaps = 46/263 (17%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKL-QELEKYPGIQTRVLDVTKKKQID 66 +I+++ A GIG A G +++ DI ++++ +L G + + DV K Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAEVIADLSTAEGRKQAIADVLAKCS-- 60 Query: 67 QFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSG 126 + +D L AG VL +++N ++ AFLP + Sbjct: 61 ------KGMDGLVLCAGLGPQTKVLG-------NVVSVNYFGATELMDAFLPALKKGHQP 107 Query: 127 NIINMSSVASSVKGV---------------------------VNRCVYSTTKAAVIGLTK 159 + +SSVAS+ Y+ +K A+ + Sbjct: 108 AAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVR 167 Query: 160 SVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAM 219 AA + + G+R N + PG +TP LQ +Q +P + GR A E+A Sbjct: 168 KRAAAWGEAGVRLNTIAPGATETPLLQAGLQ---DPRYGESIAKFVPPMGRRAEPSEMAS 224 Query: 220 LCVYLASDESAYVTGNPVIIDGG 242 + +L S ++YV G ++IDGG Sbjct: 225 VIAFLMSPAASYVHGAQIVIDGG 247 >5ILO-A nrPDB Length = 271 Score = 131 bits (329), Expect = 4e-31, Method: Composition-based stats. Identities = 53/214 (24%), Positives = 88/214 (41%), Gaps = 24/214 (11%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGA-KVIATDINES-----KLQELEKYPGIQTRVL 57 GK ++T A GIG + GA KV D+ ++ KL+ + + Sbjct: 13 FRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKM 72 Query: 58 DVTKKKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 DV KK ++ A +D++ NVAG + KD ++ +N+ + Sbjct: 73 DVANKKGVEATYEEIAKTFGNIDIVVNVAGIFND--------KDVQRTLLVNLGGIINST 124 Query: 114 KAFLPKMLAQKSGN---IINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQ 168 + LP M G ++NMSSV + + VY TKA +I T+ +A + + + Sbjct: 125 LSALPYMGKDNGGKGGIVVNMSSVVG-LDPMFIIPVYGATKAGIINFTRCLANEKYYQRS 183 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDF 202 GI+ VCPG T + PE + + Sbjct: 184 GIKFVTVCPGATMTDMFTNFTEKIIFPETSDETY 217 >4HBG-A nrPDB Length = 286 Score = 128 bits (322), Expect = 2e-30, Method: Composition-based stats. Identities = 54/276 (19%), Positives = 88/276 (31%), Gaps = 60/276 (21%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 V I+T A +GIG+A ++G I + ++ G L ++ I Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 68 FANEVER-----------------------------------------LDVLFNVAGFVH 86 + +++L N AG Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 87 HGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS-----------GNIINMSSV- 134 + MN+N S M + M+ + I+N+SS+ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 135 ASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVD-TPSLQERIQARG 193 S V VYS +KAA+ T+ +AA+ + IRC + PG V T +Q Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL----- 240 Query: 194 NPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 P EA+ + + EIA L S + Sbjct: 241 -PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 >3UCF-A nrPDB Length = 223 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 53/244 (21%), Positives = 89/244 (36%), Gaps = 28/244 (11%) Query: 1 MGRLDGKVI-ILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDV 59 MG K + ++ GIG A E V LD+ Sbjct: 2 MG--SDKTVYVVLGGTSGIGAELAKQLESEHTIVHVASRQ---------------TGLDI 44 Query: 60 TKKKQIDQFANEVERLDVLFNVAG-FVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 + +K + + + D L AG + G V+D E ++ + L K Sbjct: 45 SDEKSVYHYFETIGAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGAR 104 Query: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPG 178 + G I ++S S K V N V + AA+ TK +A + IR N + PG Sbjct: 105 YLKQ---GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAISPG 159 Query: 179 TVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVI 238 T + + + R G+ A +IAM ++ + +++Y+TG + Sbjct: 160 LTKTEAYKGMNADDRDAMYQRTQ--SHLPVGKVGEASDIAMAYLF--AIQNSYMTGTVID 215 Query: 239 IDGG 242 +DGG Sbjct: 216 VDGG 219 >3U9L-A nrPDB Length = 324 Score = 126 bits (317), Expect = 9e-30, Method: Composition-based stats. Identities = 54/241 (22%), Positives = 98/241 (40%), Gaps = 17/241 (7%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKYP-----GIQ 53 + K+I++T A+ G G+ A A A G +V N S ++ + + ++ Sbjct: 3 MSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLR 62 Query: 54 TRVLDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSM 109 T LDV + +D+ +++ R+DVL + AG + G + + ++NV S Sbjct: 63 TLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVLST 122 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 + +A LP M QK G +I +SS +S+ Y KAA+ + A + + G Sbjct: 123 QRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRWG 182 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229 I + + PG T + + AR + EEI + ++ Sbjct: 183 IETSIIVPGAF-TSGTNHFAHSGVPDDHARQAEYEAGPNAGLG--EEIKKAFAAIVPPDA 239 Query: 230 A 230 Sbjct: 240 D 240 >1SNY-A nrPDB Length = 267 Score = 123 bits (310), Expect = 7e-29, Method: Composition-based stats. Identities = 49/203 (24%), Positives = 80/203 (39%), Gaps = 27/203 (13%) Query: 9 IILTAAAQGIGQAAALAFA---REGAKVIATDINESKLQELEKYP----GIQTRVLDVTK 61 I++T +G+G A + + T N + +ELE I +D+ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRN 83 Query: 62 KKQIDQFANEVER------LDVLFNVAGFVHH-GTVLDCEEKDWDFSMNLNVRSMYLMIK 114 D+ ++E L+VLFN AG + ++ ++ N ++ K Sbjct: 84 FDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAK 143 Query: 115 AFLPKMLAQ-----------KSGNIINMSSVASSVKGVV--NRCVYSTTKAAVIGLTKSV 161 A LP + IINMSS+ S++G Y T+K+A+ TKS+ Sbjct: 144 ACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSL 203 Query: 162 AADFIQQGIRCNCVCPGTVDTPS 184 + D Q I C + PG V T Sbjct: 204 SVDLYPQRIMCVSLHPGWVKTDM 226 >2O2S-A nrPDB Length = 315 Score = 120 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 48/289 (16%), Positives = 101/289 (34%), Gaps = 50/289 (17%) Query: 4 LDGKVIILTAAAQ--GIGQAAALAFAREGAKVIAT-----------DINESKLQELEKYP 50 L G+ + A G G A A A GA+V + +L E K P Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 51 G------IQTRVLDV------------------------TKKKQIDQFANEVERLDVLFN 80 LD T K+ + ++ +D+L + Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH 126 Query: 81 VAGFVHH--GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSV 138 +L+ K + + + + S +++ F P M + G+ + +S +A+ Sbjct: 127 SLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM--NEGGSAVTLSYLAAER 184 Query: 139 KGVVNRCVYSTTKAAVIGLTKSVAADFI-QQGIRCNCVCPGTVDTPSLQERIQARGNP-- 195 S+ KAA+ T+++A + + G+R N + G + + + ++ Sbjct: 185 VVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFI 244 Query: 196 EEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWS 244 + A + R ++++ ++L S + V+G + +D G Sbjct: 245 DYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLH 293 >4Q9N-A nrPDB Length = 298 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 49/288 (17%), Positives = 99/288 (34%), Gaps = 52/288 (18%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKVIA-------------------------- 35 L GK+ + G G A A GA ++ Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 36 ------------TDINESKLQELEKYPGIQTRVLDV---TKKKQIDQFANEVERLDVLFN 80 D + +++ + R D+ T + ++Q +D+L + Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 81 VAGFVHH--GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSV 138 +LD K + +++ + S ++ F P M A + I+++ +AS Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNA--GASTISLTYLASMR 183 Query: 139 KGVVNRCVYSTTKAAVIGLTKSVAADFIQQ-GIRCNCVCPGTVDTPSLQERIQARGNPEE 197 + KAA+ TK +A + ++ G+R N + G P +A G E Sbjct: 184 AVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAG----PLASRAGKAIGFIER 239 Query: 198 ARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + AE++ +L S ++ +TG + +D G ++ Sbjct: 240 MVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGANV 287 >5TQV-A nrPDB Length = 233 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 49/184 (26%), Positives = 83/184 (45%), Gaps = 10/184 (5%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 K +++ A++G+G+ + R+G VIAT +++ L L G LD+T+ +QI Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL-GAHAHALDITQPEQIA 68 Query: 67 QFANEV--ERLDVLFNVAGFVHHGT--VLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 ++ ERLDV V+G T V D+D M+ NVR ++ LP ++ Sbjct: 69 ALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLP-LVE 127 Query: 123 QKSGNIINMSSVASSVKGVVNRC--VYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 180 G + +SS S+ +Y +KAA+ + + A + C + PG V Sbjct: 128 DARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLR--IASLQTRHAACISLHPGWV 185 Query: 181 DTPS 184 T Sbjct: 186 RTDM 189 >3KZV-A nrPDB Length = 254 Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats. Identities = 50/209 (23%), Positives = 100/209 (47%), Gaps = 14/209 (6%) Query: 6 GKVIILTAAAQGIGQAAA-LAFAREGAKVI-ATDINESKLQELEKYPGIQ--TRVLDVTK 61 GKVI++T ++GIG++ + F+ + V+ +E+ L++L++ G + V D+T+ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 62 KKQIDQFANEV----ERLDVLFNVAGFV-HHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + Q N ++D L AG + V + + W ++N S+ ++ Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIA 121 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 LP++ GN++ +SS A ++ + Y ++KAA+ ++A + ++ ++ V Sbjct: 122 LPELKKTN-GNVVFVSSDACNM-YFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVA 177 Query: 177 PGTVDTPSLQERIQARGNPEEARNDFLKR 205 PG VDT Q I+ P + LK Sbjct: 178 PGIVDTDM-QVNIRENVGPSSMSAEQLKM 205 >1ENP-A nrPDB Length = 312 Score = 117 bits (293), Expect = 5e-27, Method: Composition-based stats. Identities = 50/287 (17%), Positives = 102/287 (35%), Gaps = 52/287 (18%) Query: 4 LDGKVIILTAAA--QGIGQAAALAFAREGAKV-------------------------IAT 36 L GK + A G G A A + A GA++ + Sbjct: 16 LRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLP 75 Query: 37 DINESKLQELEKYPGIQTRVLDV----------------TKKKQIDQFANEVERLDVLFN 80 D + +++++ + DV T ++ + + +D+L + Sbjct: 76 DGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILVH 135 Query: 81 VAGFVHH--GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSV 138 +L+ K + +++ + S ++ FLP M G I+++ +AS Sbjct: 136 SLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM--NPGGASISLTYIASER 193 Query: 139 KGVVNRCVYSTTKAAVIGLTKSVAADFIQQ-GIRCNCVCPGTVDTPSLQERIQARGNPEE 197 S+ KAA+ T+ +A + ++ IR N + G P +A G + Sbjct: 194 IIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAG----PLGSRAAKAIGFIDT 249 Query: 198 ARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWS 244 + TA+E+ +L S ++ +TG + +D G + Sbjct: 250 MIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLN 296 >1B15-A nrPDB Length = 254 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 49/218 (22%), Positives = 84/218 (38%), Gaps = 24/218 (11%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAK-VIATDINE-----SKLQELEKYPGIQTRVL 57 L K +I AA GIG + + K + D E ++L+ + I Sbjct: 3 LTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHTY 62 Query: 58 DVT-----KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 DVT KK + + ++++ +D+L N AG ++ + ++ +N + Sbjct: 63 DVTVPVAESKKLLKKIFDQLKTVDILINGAGI--------LDDHQIERTIAINFTGLVNT 114 Query: 113 IKAFLPKMLAQKSG---NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 A L +K G I N+ SV + VYS +KAAV+ T S+A G Sbjct: 115 TTAILDFWDKRKGGPGGIIANICSVTG-FNAIHQVPVYSASKAAVVSFTNSLAKLAPITG 173 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK 207 + + PG TP + + + E + L Sbjct: 174 VTAYSINPGITRTPLVHT-FNSWLDVEPRVAELLLSHP 210 >2NTV-A nrPDB Length = 268 Score = 110 bits (276), Expect = 5e-25, Method: Composition-based stats. Identities = 52/267 (19%), Positives = 100/267 (37%), Gaps = 28/267 (10%) Query: 2 GRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKL-QELEKYPGIQT--RV 56 G L+GK I+++ I A GA+++ T + +L Q + + Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIE 61 Query: 57 LDVTKKKQIDQFANEVE-------RLDVLFNVAGFVH-----HGTVLDCEEKDWDFSMNL 104 LDV ++ + A V +LD + + GF+ D +D +++ Sbjct: 62 LDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGIHI 121 Query: 105 NVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 + S + KA L ++ G+I+ M + + + K+A+ + + VA + Sbjct: 122 STYSYASLAKALL--LIMNSGGSIVGM--DFDPTRAMPAYNWMTVAKSALESVNRFVARE 177 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEA------RNDFLKRQKTG-RFATAEEI 217 + G+R N V G + T ++ + E + +R G + Sbjct: 178 AGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPV 237 Query: 218 AMLCVYLASDESAYVTGNPVIIDGGWS 244 A L S+ TG+ + DGG S Sbjct: 238 AKTVCALLSEWLPATTGSIIYADGGAS 264 >2HRB-A nrPDB Length = 274 Score = 110 bits (276), Expect = 5e-25, Method: Composition-based stats. Identities = 49/260 (18%), Positives = 77/260 (29%), Gaps = 64/260 (24%) Query: 7 KVIILTAAAQGIGQAAALAFARE--GAKVIATDINESKLQEL-----EKYPGIQTRVLDV 59 +V ++T A +GIG A A R+ G V+ T + ++ Q + + LD+ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSG-DVVLTARDVARGQAAVQQLQAEGLSPRFHQLDI 61 Query: 60 TKKKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMN--LNVRSMYLMI 113 + I E L+VL N A D D M N + M Sbjct: 62 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKS--DDPMPFDIKAEMTLKTNFFATRNMC 119 Query: 114 KAFLPKMLAQKSGNIINMSSV--------------------------------------- 134 LP M G ++N+SS+ Sbjct: 120 NELLPIMK--PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTK 177 Query: 135 --ASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ----GIRCNCVCPGTVDTPSLQER 188 +G N Y +K V L++ +A ++ I N CPG V T + Sbjct: 178 NEVHEREGWPN-SPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKD 236 Query: 189 IQARGNPEEARNDFLKRQKT 208 +L Sbjct: 237 SIRTVEEGAETPVYLALLPP 256 >4OYR-A nrPDB Length = 289 Score = 110 bits (275), Expect = 7e-25, Method: Composition-based stats. Identities = 57/267 (21%), Positives = 100/267 (37%), Gaps = 28/267 (10%) Query: 2 GRLDGKVIILTA--AAQGIGQAAALAFAREGAKVIATDINESKL-QELEKYPGIQT--RV 56 G LDGK I+++ I A +GA+++ T + +L Q + + Sbjct: 23 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLE 82 Query: 57 LDVTKKKQIDQFANEVE-------RLDVLFNVAGFVH-----HGTVLDCEEKDWDFSMNL 104 LDV ++ + A V +LD + + GF+ D D +++ Sbjct: 83 LDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHI 142 Query: 105 NVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 + S M KA LP M G+I+ M + + + K+A+ + + VA + Sbjct: 143 SAYSYASMAKALLPIM--NPGGSIVGM--DFDPSRAMPAYNWMTVAKSALESVNRFVARE 198 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEA------RNDFLKRQKTG-RFATAEEI 217 + G+R N V G + T ++ + E + +R G A + Sbjct: 199 AGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPV 258 Query: 218 AMLCVYLASDESAYVTGNPVIIDGGWS 244 A L SD TG+ + DGG Sbjct: 259 AKTVCALLSDWLPATTGDIIYADGGAH 285 >5L51-A nrPDB Length = 324 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 49/296 (16%), Positives = 84/296 (28%), Gaps = 94/296 (31%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK--------LQELEKYPG--IQT 54 + ++T A +GIG A +G VI +E + ++EL G + + Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 55 RVLDVTKKKQIDQFAN----EVERLDVLFNVAGFVH------------------------ 86 + LDV + + + LD+L N AG Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSG 133 Query: 87 -----------HGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVA 135 G +++ + + N + +A +P + S I+N+SS Sbjct: 134 AAKTEPYHPKATGRLVE-TVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTL 192 Query: 136 SSV------------------------------------------KGVVNRCVYSTTKAA 153 SS+ + + Y +KAA Sbjct: 193 SSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAA 252 Query: 154 VIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209 + T+ +A + R N VCPG T Q L G Sbjct: 253 LNAYTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQFTDAEAAEAPVKLALLPQG 306 >2PTG-A nrPDB Length = 319 Score = 104 bits (261), Expect = 3e-23, Method: Composition-based stats. Identities = 47/302 (15%), Positives = 100/302 (33%), Gaps = 63/302 (20%) Query: 4 LDGKVIILTAA--AQGIGQAAALAFAREGAKV--------------------------IA 35 L GK + + G G A GA+V A Sbjct: 7 LRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 36 TDINESKLQELEKYP------------GIQTRVLDV----------------TKKKQIDQ 67 + + E + P + DV T + + Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEA 126 Query: 68 FANEVERLDVLFNVAGFVHH--GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS 125 +V ++D+L + +L K + +++ + S +++ FLP M Sbjct: 127 VRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE--G 184 Query: 126 GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ-QGIRCNCVCPGTVDTPS 184 G+ + +S +AS S+ KAA+ +++A + + + +R NC+ G + + + Sbjct: 185 GSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSRA 244 Query: 185 LQERIQARGNP--EEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGG 242 +A + A + + ++++ ++L S + VTG + +D G Sbjct: 245 ASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDNG 304 Query: 243 WS 244 Sbjct: 305 LH 306 >3BHI-A nrPDB Length = 276 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 51/258 (19%), Positives = 77/258 (29%), Gaps = 62/258 (24%) Query: 8 VIILTAAAQGIGQAAALAFAR--EGAKVIATDINESKLQEL-----EKYPGIQTRVLDVT 60 V ++T +GIG A R G V+ T + ++ Q + + LD+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSG-DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 64 Query: 61 KKKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDF--SMNLNVRSMYLMIK 114 + I E LDVL N AG V D +M N + Sbjct: 65 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFK--VADPTPFHIQAEVTMKTNFFGTRDVCT 122 Query: 115 AFLPKMLAQKSGNIINMSSVAS-----------------------SVKGVVN-------- 143 LP + Q G ++N+SS+ S + G++N Sbjct: 123 ELLPLIKPQ--GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKK 180 Query: 144 ---------RCVYSTTKAAVIGLTKSVAADFIQQ----GIRCNCVCPGTVDTPSLQERIQ 190 Y TK V L++ A +Q I N CPG V T + Sbjct: 181 GVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKAT 240 Query: 191 ARGNPEEARNDFLKRQKT 208 +L Sbjct: 241 KSPEEGAETPVYLALLPP 258 >1N5D-A nrPDB Length = 288 Score = 101 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 47/257 (18%), Positives = 76/257 (29%), Gaps = 60/257 (23%) Query: 7 KVIILTAAAQGIGQAAALAFAREGA-KVIATDINESKLQEL-----EKYPGIQTRVLDVT 60 +V ++T A +GIG A R+ A V+ T + ++ Q + + LD+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 61 KKKQIDQ----FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDF--SMNLNVRSMYLMIK 114 + I E LDVL N A + + +M N + Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAFQ--LDNPTPFHIQAELTMKTNFMGTRNVCT 122 Query: 115 AFLPKMLAQKSGNIINMSSVAS-----------------------SVKGVVNR------- 144 LP + Q G ++N+SS + G++N+ Sbjct: 123 ELLPLIKPQ--GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTKN 180 Query: 145 ----------CVYSTTKAAVIGLTKSVAADF----IQQGIRCNCVCPGTVDTPSLQERIQ 190 Y TK V L++ A I N CPG V T + Sbjct: 181 GVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDMGGPKAP 240 Query: 191 ARGNPEEARNDFLKRQK 207 +L Sbjct: 241 KSPEVGAETPVYLALLP 257 >3F4B-A nrPDB Length = 323 Score = 99.1 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 81/207 (39%), Gaps = 23/207 (11%) Query: 60 TKKKQIDQFANEVERLDVLFNVA--GFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 + ++ + N+ ++ +L + G ++LD + +++ + S+ + K F Sbjct: 106 SIEEVANLIYNKYGKISMLVHSLANGREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFC 165 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI-QQGIRCNCVC 176 M G++++++ AS S+ KAA+ T+ +A + IR N + Sbjct: 166 KFM--NSGGSVVSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTIS 223 Query: 177 PGTVDTPSLQERIQARGNP------------------EEARNDFLKRQKTGRFATAEEIA 218 G + + + + N + A + K + + ++ Sbjct: 224 AGPLKSRAATAINKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVG 283 Query: 219 MLCVYLASDESAYVTGNPVIIDGGWSL 245 + +L S ES+ VTG + +D G ++ Sbjct: 284 SVASFLLSKESSAVTGQTIYVDNGLNI 310 >1MG5-A nrPDB Length = 255 Score = 98.7 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 47/216 (21%), Positives = 78/216 (36%), Gaps = 23/216 (10%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAK-VIATDINE-----SKLQELEKYPGIQTRVL 57 L K +I A GIG + + K ++ D E ++L+ + + Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPY 63 Query: 58 DVTKK-----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 DVT K + +++ +DVL N AG ++ + ++ +N + Sbjct: 64 DVTVPIAETTKLLKTIFAQLKTVDVLINGAGI--------LDDHQIERTIAVNYTGLVNT 115 Query: 113 IKAFLPKMLAQKSG---NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQG 169 A L +K G I N+ SV + VYS TKAAV+ T S+A G Sbjct: 116 TTAILDFWDKRKGGPGGIICNIGSVTG-FNAIYQVPVYSGTKAAVVNFTSSLAKLAPITG 174 Query: 170 IRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKR 205 + V PG T + + + L Sbjct: 175 VTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAH 210 >3O26-A nrPDB Length = 311 Score = 97.2 bits (241), Expect = 5e-21, Method: Composition-based stats. Identities = 47/261 (18%), Positives = 78/261 (29%), Gaps = 85/261 (32%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL------EKYPGIQTRVLDVT 60 + ++T +GIG + G V+ T + +K E + + LDVT Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 61 KK----KQIDQFANE-VERLDVLFNVAGFVHH--------GTVLDCEEKDWDFS------ 101 + F +LD+L N AG + D E + Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYEKP 132 Query: 102 ----------------MNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVN-- 143 + +N + + + +P + S I+N+SS S+K V N Sbjct: 133 EAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVSNET 192 Query: 144 ----------------------------------------RCVYSTTKAAVIGLTKSVAA 163 Y+T+KA + T+ +A Sbjct: 193 ALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRVLAN 252 Query: 164 DFIQQGIRCNCVCPGTVDTPS 184 + NCVCPG V T Sbjct: 253 KIPKFQ--VNCVCPGLVKTEM 271 >5LCX-A nrPDB Length = 316 Score = 94.5 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 51/295 (17%), Positives = 77/295 (26%), Gaps = 94/295 (31%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV---------L 57 + ++T A +GIG A +G VI T NE + E + + V L Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 58 DVTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCE------EKDWDFSMN---- 103 DVT + A ++ +LD+L N AG V D E D+ Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAG 127 Query: 104 ---------------------------LNVRSMYLMIKAFLPKMLAQKSGNIINMSSVAS 136 N + +A +P + S I+N+SS Sbjct: 128 AKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSFG 187 Query: 137 ------------------------------------------SVKGVVNRCVYSTTKAAV 154 + + +KAA+ Sbjct: 188 SLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAAL 247 Query: 155 IGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTG 209 TK A + R N +CPG T L G Sbjct: 248 NAYTKIAAKKYPSF--RINAICPGYAKTDITFHAGPLSVAEAAQVPVKLALLPDG 300 >5WQO-A nrPDB Length = 234 Score = 89.9 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 75/188 (39%), Gaps = 13/188 (6%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINES---KLQELEKYPG--IQTRVLDVTKK 62 +++ A++GIG A AF + GA+V A LQ L + G +Q D+ + Sbjct: 8 NVLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQH 67 Query: 63 KQIDQFANEVE--RLDVLFNVAGFVHH--GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 ++ + R+D L AG V + + + N + + +A Sbjct: 68 DCAERIGEMLGERRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARALSG 127 Query: 119 KMLAQKSGNIINMSSVASSVK--GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 ++ + G + MSS +S+ +Y +KAA+ L +S +F + + Sbjct: 128 RV--SRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLLH 185 Query: 177 PGTVDTPS 184 PG V T Sbjct: 186 PGWVRTEM 193 >2O2Y-A nrPDB Length = 349 Score = 89.5 bits (221), Expect = 1e-18, Method: Composition-based stats. Identities = 35/226 (15%), Positives = 80/226 (35%), Gaps = 45/226 (19%) Query: 63 KQIDQFA-NEVERLDVLFNVAGFVHH--GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 + + + ++++L + +L+ K + +++ + S+ + K F+ Sbjct: 113 EDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNI 172 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ-QGIRCNCVCPG 178 M Q +II+++ AS S+ KAA+ T+ +A + IR N + G Sbjct: 173 MKPQS--SIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAG 230 Query: 179 TVDTPS-------------------------LQERIQARGNPEEARNDFLKR-------- 205 + + + + + G EE +N + Sbjct: 231 PLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFIDYAI 290 Query: 206 ------QKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 + + +I + +L S ES +TG + +D G ++ Sbjct: 291 EYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNI 336 >4Z3K-A nrPDB Length = 275 Score = 85.6 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 83/212 (39%), Gaps = 26/212 (12%) Query: 8 VIILTAAAQGIGQ---AAALAFAREGAKVIATDINESKLQELEKYPGIQT-------RVL 57 V +LT A++G G+ + G+ ++ + N+ L++LE G + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 58 DVTKKKQIDQFANEVERLD--------VLFNVAGFVHH--GTVLDCEEK-DWDFSMNLNV 106 D+ + + Q + L +L N AG + +D + + LN+ Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 142 Query: 107 RSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 SM + + L ++N+SS+ + ++ +Y KAA L + +A + Sbjct: 143 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCA-LQPFKGWALYCAGKAARDMLFQVLALE 201 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPE 196 + +R PG +DT Q + +P+ Sbjct: 202 --EPNVRVLNYAPGPLDTDMQQLARETSVDPD 231 >4HWK-A nrPDB Length = 288 Score = 85.6 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 83/212 (39%), Gaps = 26/212 (12%) Query: 8 VIILTAAAQGIGQ---AAALAFAREGAKVIATDINESKLQELEKYPGIQT-------RVL 57 V +LT A++G G+ + G+ ++ + N+ L++LE G + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 58 DVTKKKQIDQFANEVERLD--------VLFNVAGFVHH--GTVLDCEEK-DWDFSMNLNV 106 D+ + + Q + L +L N AG + +D + + LN+ Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 155 Query: 107 RSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 SM + + L ++N+SS+ + ++ +Y KAA L + +A + Sbjct: 156 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCA-LQPFKGWALYCAGKAARDMLFQVLALE 214 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPE 196 + +R PG +DT Q + +P+ Sbjct: 215 --EPNVRVLNYAPGPLDTDMQQLARETSVDPD 244 >1OAA-A nrPDB Length = 259 Score = 78.7 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 48/212 (22%), Positives = 90/212 (42%), Gaps = 26/212 (12%) Query: 8 VIILTAAAQGIGQAAALAFARE---GAKVIATDINESKLQELEKYPGIQ-------TRVL 57 V +LT A++G G+A A AR G+ ++ + +ES L++L++ G Q Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 58 DVTKKKQIDQFANEVERLD--------VLFNVA---GFVHHGTVLDCEEKDWDFSMNLNV 106 D+ + + + + V L +L N A G V G + + + + LN+ Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 127 Query: 107 RSMYLMIKAFLPKMLAQKSGN--IINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 SM + L + ++N+SS+ + ++ +Y KAA L + +AA+ Sbjct: 128 TSMLCLTSGTLNAFQDSPGLSKTVVNISSLCA-LQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPE 196 + +R PG +D Q + +PE Sbjct: 187 --EPSVRVLSYAPGPLDNDMQQLARETSKDPE 216 >2PK3-A nrPDB Length = 321 Score = 64.1 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 39/257 (15%), Positives = 81/257 (31%), Gaps = 41/257 (15%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 ++T A +G+ A + +V T N K P ++ LD+ +++ + Sbjct: 14 RALITGVAGFVGKYLANHLTEQNVEVFGTSRNNE-----AKLPNVEMISLDIMDSQRVKK 68 Query: 68 FANEVERLDVLFNVAGFVHHGTVLDCEEKDW---DFSMNLNVRSMYLMIKAFLPKMLAQK 124 ++++ D +F++A + W + + NV ++ A L Sbjct: 69 VISDIKP-DYIFHLAAKSSV-------KDSWLNKKGTFSTNVFGTLHVLDAVRDSNLDC- 119 Query: 125 SGNIINMSSVASSVKGVVN------------RCVYSTTKAAVIGLTKSVAADFIQQGI-- 170 I+ + S + Y +KA+V L + + I Sbjct: 120 --RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDIIHT 177 Query: 171 -RCNCVCP----GTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 N + P G V ++ + +E + F +I +L Sbjct: 178 RTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAY-WLL 236 Query: 226 SDESAYVTGNPVIIDGG 242 S TG+ + G Sbjct: 237 SQYGK--TGDVYNVCSG 251 >4LIS-A nrPDB Length = 371 Score = 64.1 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 33/167 (19%), Positives = 53/167 (31%), Gaps = 28/167 (16%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATD----INESKLQELEKYPGIQT--RVLDVTKK 62 +++T IG LA G KV+ D + L +E G + LDVT + Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 D+ +D + + A G + ++NV + L M+ Sbjct: 66 AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLD----YYHVNVYGTICL----LRSMVR 117 Query: 123 QKSGNIINMSS--VASSVKGVVNR------------CVYSTTKAAVI 155 NI+ SS V + Y TK A+ Sbjct: 118 HNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >1DIR-A nrPDB Length = 241 Score = 60.6 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 75/199 (37%), Gaps = 25/199 (12%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 + + +++ +G AF V + D+ E++ E + ++ D + +Q Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENE----EASASVIVKMTD-SFTEQ 60 Query: 65 IDQFANEVERL------DVLFNVAGFVHHGTVLDCEEKD-----WDFSMNLNVRSMYLMI 113 DQ EV +L D + VAG G W S+ + S +L Sbjct: 61 ADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLAT 120 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA--ADFIQQGIR 171 K K G ++ ++ +++ G Y K AV L +S+A + G Sbjct: 121 KHL-------KEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAA 173 Query: 172 CNCVCPGTVDTPSLQERIQ 190 V P T+DTP ++ + Sbjct: 174 AIAVLPVTLDTPMNRKSMP 192 >3ORF-A nrPDB Length = 251 Score = 57.5 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 28/194 (14%), Positives = 70/194 (36%), Gaps = 23/194 (11%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 K I++ + +G F + I+ D E + + + +++I Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDFRE-------NPNADHSFTIKDSGEEEIK 75 Query: 67 QFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDF----SMNLNVRSMYLMIKAFLP 118 ++ ++D AG G + ++ +++N+ S + Sbjct: 76 SVIEKINSKSIKVDTFVCAAGGWSGG---NASSDEFLKSVKGMIDMNLYSAFASAHIGAK 132 Query: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI--QQGIRCNCVC 176 + G + ++ ++++ Y TKAA + K +A++ G + Sbjct: 133 LL---NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGIL 189 Query: 177 PGTVDTPSLQERIQ 190 P T+DTP+ ++ + Sbjct: 190 PVTLDTPTNRKYMS 203 >1OOE-A nrPDB Length = 236 Score = 57.1 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 43/197 (21%), Positives = 83/197 (42%), Gaps = 20/197 (10%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 GKV I+ +G A F + G V+ D++ + + + T+++Q Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLS---ANDQADSNILVDGNKNWTEQEQ 58 Query: 65 --IDQFANEVER--LDVLFNVAGFVHHGTVLDCEEKDW----DFSMNLNVRSMYLMIKAF 116 ++Q A+ ++ +D +F VAG G+ KD+ D + +V S + K Sbjct: 59 SILEQTASSLQGSQVDGVFCVAGGWAGGSA---SSKDFVKNADLMIKQSVWSSAIAAKLA 115 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA--DFIQQGIRCNC 174 + G ++ ++ A+++ + Y KAAV LT S+AA + Sbjct: 116 TTHLK---PGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNSAVLT 172 Query: 175 VCPGTVDTPSLQERIQA 191 + P T+DTP ++ + Sbjct: 173 IMPVTLDTPMNRKWMPN 189 >1Z45-A nrPDB Length = 699 Score = 53.3 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 28/175 (16%), Positives = 57/175 (32%), Gaps = 29/175 (16%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAK-VIATDINESKLQELEKY-----PGIQTRVLDVT 60 K++++T A IG + G V+A +++ S + + I +D+ Sbjct: 12 KIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLC 71 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 +K +++ E ++D + + AG G + N+ ++ L M Sbjct: 72 DRKGLEKVFKEY-KIDSVIHFAGLKAVGESTQIPL----RYYHNNILGTVVL----LELM 122 Query: 121 LAQKSGNIINMSS--VASSVKGVVNR------------CVYSTTKAAVIGLTKSV 161 + SS V N Y TK A+ + + Sbjct: 123 QQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDL 177 >3SLK-A nrPDB Length = 795 Score = 53.3 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 19/166 (11%), Positives = 52/166 (31%), Gaps = 20/166 (12%) Query: 8 VIILTAAAQGIGQAAALAFA-REGAK-VIATDINESKLQELEKY--------PGIQTRVL 57 +++T +G A G + ++ + + + Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 58 DVTKKKQIDQFANEVE---RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114 DV ++ + + + L + + AG + G + D + V +++ Sbjct: 592 DVADRETLAKVLASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLLE 651 Query: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS 160 P + ++ SSV+ + G + Y+ + + L + Sbjct: 652 LIDPDV------ALVLFSSVSGVL-GSGGQGNYAAANSFLDALAQQ 690 Score = 27.1 bits (59), Expect = 6.9, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 20/117 (17%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFARE-GAKVIATDINES-KLQELEKYPGIQTRVLDV 59 G G+ +++ +AA G+G A A+ AR GA+V AT + + EL + +R D Sbjct: 342 GLRPGESLLVHSAAGGVGMA-AIQLARHLGAEVYATASEDKWQAVELSREHLASSRTCDF 400 Query: 60 TKKKQIDQFANEVE--RLDVLFNV-AG---------FVHHGTVLDCEEKDWDFSMNL 104 QF +DV+ N AG G L+ + D + + Sbjct: 401 E-----QQFLGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFLELGKTDVRDPVEV 452 >1VL0-A nrPDB Length = 292 Score = 51.7 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 29/163 (17%), Positives = 58/163 (35%), Gaps = 36/163 (22%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQF 68 I++T A +G+ + +VI TD+ + LD+T +++F Sbjct: 15 ILITGANGQLGREIQKQLKGKNVEVIPTDVQD----------------LDITNVLAVNKF 58 Query: 69 ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNI 128 NE ++ +V+ N A +D E+ +D + +N + A I Sbjct: 59 FNE-KKPNVVINCAAHT----AVDKCEEQYDLAYKINAIGPKNLAAAAYSV-----GAEI 108 Query: 129 INMSSV----------ASSVKGVVNRCVYSTTKAAVIGLTKSV 161 + +S+ + V + Y TK K++ Sbjct: 109 VQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >2Q1W-A nrPDB Length = 333 Score = 51.7 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 32/191 (16%), Positives = 61/191 (31%), Gaps = 26/191 (13%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-LEKYPGIQTRVLDVTKKKQI 65 K + +T IG A G KV+ D + +E L+ +P + + + Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSIADHALV 81 Query: 66 DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS 125 +Q +++ D + + A DW N +++A Sbjct: 82 NQLIGDLQP-DAVVHTAASYKD-------PDDWYNDTLTNCVGGSNVVQAA----KKNNV 129 Query: 126 GNIINM-SSVASSVKG-----------VVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 G + +++ VK Y+ +K+A + DF+ + N Sbjct: 130 GRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGLDFVTFRL-AN 188 Query: 174 CVCPGTVDTPS 184 V P V P Sbjct: 189 VVGPRNVSGPL 199 >6BWL-A nrPDB Length = 328 Score = 50.6 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 37/262 (14%), Positives = 84/262 (32%), Gaps = 43/262 (16%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATD--INESKLQELEKYPGIQTRVL---DVTKKK 63 I++T A IG+ ++ +V D N + E + + D+ KK Sbjct: 3 ILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDKK 62 Query: 64 QIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK---- 119 + Q D+ +++A ++ + D + + + +++ L Sbjct: 63 LVAQLFEN-NSFDLCYHLAASIN----VQDSIDDARATFENDTIGTFNLLEQCLNYDVKM 117 Query: 120 ------MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 M+ K+ NI +S + + Y+ +K A + S + + Sbjct: 118 VFMSTCMVYDKATNIQGIS----ELDPIKPASPYAGSKIAAENMVLSY---YYAYKLPVV 170 Query: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFAT---------AEEIAM--LCV 222 + P P Q+ G N+ L + E+ A + Sbjct: 171 VIRPFNTYGP-FQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCADFVVAA 229 Query: 223 YLASDESAYV----TGNPVIID 240 ++ + ++ TG + I+ Sbjct: 230 GYSAKANGHIINAGTGQDISIN 251 >2NNL-D nrPDB Length = 337 Score = 50.2 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 42/265 (15%), Positives = 88/265 (33%), Gaps = 46/265 (17%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE---KYPGIQTRV- 56 MG + + +T A+ IG + G V AT + + +++++ P +T + Sbjct: 1 MGS-QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLT 59 Query: 57 ---LDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKD-WDFSMNLNVRSMYLM 112 D+ + D+ G H T +D E KD + + + M + Sbjct: 60 LWKADLADEGSFDEAIK---------GCTGVFHVATPMDFESKDPENEVIKPTIEGMLGI 110 Query: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVY----------STTK---AAVIGLTK 159 +K+ + ++ SS + VY K A + ++K Sbjct: 111 MKSCAAAKTVR---RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSK 167 Query: 160 SVAADFI-----QQGIRCNCVCPGTVDTPSLQERIQ----ARGNPEEARNDFLKRQKTGR 210 ++A + I + P V P + + +P + G+ Sbjct: 168 TLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQ 227 Query: 211 FATAEEIAMLCVYLASD---ESAYV 232 F +++ +YL + E Y+ Sbjct: 228 FVHLDDLCNAHIYLFENPKAEGRYI 252 >1UDA-A nrPDB Length = 338 Score = 49.4 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 56/167 (33%), Gaps = 26/167 (15%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATD----INESKLQELEKYPGIQTRVL--DVTK 61 +++T + IG + + G VI D S L +E+ G + D+ Sbjct: 2 RVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRN 61 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 + + + ++ +D + + AG G + + +D NV +I A M Sbjct: 62 EALMTEILHDHA-IDTVIHFAGLKAVGESVQKPLEYYDN----NVNGTLRLISA----MR 112 Query: 122 AQKSGNIINMSS-----------VASSVKGVVNRCVYSTTKAAVIGL 157 A N I SS S + Y +K V + Sbjct: 113 AANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQI 159 >3RFT-A nrPDB Length = 267 Score = 49.0 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 22/165 (13%), Positives = 50/165 (30%), Gaps = 32/165 (19%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQID 66 K +++T AA +G+ A + D++ P + D+ ++ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSPLDP----AGPNEECVQCDLADANAVN 59 Query: 67 QFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSG 126 D + ++ G ++ + N+ +Y + +A A Sbjct: 60 AMVA---GCDGIVHLGGISVEKP--------FEQILQGNIIGLYNLYEAA----RAHGQP 104 Query: 127 NIINMSS------------VASSVKGVVNRCVYSTTKAAVIGLTK 159 I+ SS + V + +Y +K L + Sbjct: 105 RIVFASSNHTIGYYPQTERLGPDVPARPD-GLYGVSKCFGENLAR 148 >1I3M-A nrPDB Length = 348 Score = 48.6 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 23/178 (12%), Positives = 56/178 (31%), Gaps = 36/178 (20%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATD----------INESKLQELEKYPG--IQTRV 56 +++T A IG L G + D L+ +++ G ++ Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64 Query: 57 LDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 +D+ + + + + + + + AG G + +N+ + Sbjct: 65 MDILDQGALQRLFKKYSFM-AVIHFAGLKAMGESVQKPLD----YYRVNLTGTIQL---- 115 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNR-------------CVYSTTKAAVIGLTKSV 161 L M A N++ S +++V G Y +K + + + + Sbjct: 116 LEIMKAHGVKNLVF--SSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDL 171 >4G5H-A nrPDB Length = 363 Score = 48.3 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 22/159 (13%), Positives = 60/159 (37%), Gaps = 20/159 (12%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAK-VIATDINESKLQELEKYPG---IQTRV 56 MG D K++++T G A F K + +E K ++ K ++ + Sbjct: 21 MGF-DDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYI 79 Query: 57 LDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 DV + ++ + +D +F+ A + + ++ N+ ++++ Sbjct: 80 GDVRDSQSVETAMRD---VDYVFHAAALKQVPSCEFFPVE----AVKTNIIGTENVLQSA 132 Query: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVI 155 + + + + +I +S+ ++ +KA + Sbjct: 133 IHQNVKK----VICLSTDKAAYP----INAMGISKAMME 163 >2GN9-A nrPDB Length = 344 Score = 46.7 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 55/150 (36%), Gaps = 14/150 (9%) Query: 4 LDGKVIILTAAAQGIGQAAALA-FAREGA-KVIATDINESKLQELEKYPGIQTRVLDVTK 61 LD + I++T G+ A K+I +E K E+ + Sbjct: 19 LDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRFFIGD 78 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 + +++ +E +D+ + A H + + + + N+ +I A L + Sbjct: 79 VRDLERLNYALEGVDICIHAAAL-KHVPIAEYNPLE---CIKTNIMGASNVINACLKNAI 134 Query: 122 AQKSGNIINMSSVASSVKGVVNRCVYSTTK 151 +Q +I +S+ ++ +Y TK Sbjct: 135 SQ----VIALSTDKAANP----INLYGATK 156 >1ZZE-A nrPDB Length = 342 Score = 45.2 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 52/146 (35%), Gaps = 20/146 (13%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL-----EKYPGI--QTRVL 57 +G ++++T A + G KV T + SKL L KYPG V Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVE 69 Query: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 D+ K+ D+ AG H +V+ K +D + + ++A Sbjct: 70 DMLKQGAYDEVIK---------GAAGVAHIASVVSFSNK-YDEVVTPAIGGTLNALRAAA 119 Query: 118 PKMLAQKSGNIINMSSVASSVKGVVN 143 ++ + SS S++ N Sbjct: 120 ATPSVKRF---VLTSSTVSALIPKPN 142 >5K1S-A nrPDB Length = 362 Score = 44.8 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 36/75 (48%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 G+ +++T A+ G+G ++ +GA+VIA +E+K+Q L++ + V Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFAS 242 Query: 65 IDQFANEVERLDVLF 79 + + +DV Sbjct: 243 DVRKRTQGAGVDVAV 257 >4PVC-A nrPDB Length = 342 Score = 44.8 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 24/136 (17%), Positives = 52/136 (38%), Gaps = 16/136 (11%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT-----RVLDVTKKK 63 + ++ A I Q +E KVI + ++ K + L + G V D++K Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 64 QIDQFANEVER-LDVLFNVAGFVHHGTVLDCEEKDWDFSM-NLN-VRSMYLMIKAFLPKM 120 D + + + ++ + A D + + D + +N V+ + IK + Sbjct: 63 AFDHVFQKHGKDIKIVLHTA----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 Query: 121 LAQKSGNIINMSSVAS 136 + ++ SS A+ Sbjct: 119 VE----RVVLTSSYAA 130 >3ENK-A nrPDB Length = 341 Score = 44.4 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATD----INESKLQELEKYPGI--QTRVLDVTK 61 I++T A IG A+ G V+ D + +EK G DV+ Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSD 66 Query: 62 KKQIDQFANE 71 ++ + + + Sbjct: 67 ERALARIFDA 76 >1RKX-A nrPDB Length = 357 Score = 44.0 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 32/199 (16%), Positives = 71/199 (35%), Gaps = 33/199 (16%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYP----GIQTRVLDVT 60 GK + +T G +L GA V + + L + G+Q+ + D+ Sbjct: 8 QGKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVADGMQSEIGDIR 67 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 + ++ + E + +++F++A ++ + + + NV +++A Sbjct: 68 DQNKLLESIREFQP-EIVFHMAA----QPLVRLSYSEPVETYSTNVMGTVYLLEA----- 117 Query: 121 LAQKSG--NIINMSSVAS-----------SVKGVVNRCVYSTTKAAVIGLTKSVA----- 162 + G ++N++S + + YS +K +T S Sbjct: 118 IRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRNSFFN 177 Query: 163 -ADFIQQGIRCNCVCPGTV 180 A++ Q G V G V Sbjct: 178 PANYGQHGTAVATVRAGNV 196 >5B6K-A nrPDB Length = 366 Score = 43.3 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 48/149 (32%), Gaps = 10/149 (6%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT-----RVLDVTKK 62 + ++ A I Q + KVI + + K L+ V D++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 D + + D+ +H + D + + + + I + K A Sbjct: 83 TAFDHVFEKHGK-DIKV----VLHTASPFHFNTTDIEKDLLIPAVNGTKGILESIKKYAA 137 Query: 123 QKSGNIINMSSVASSVKGVVNRCVYSTTK 151 Q ++ SS A++ V ++K Sbjct: 138 QTVERVVVTSSFAANTSTVDMFYAKDSSK 166 >1R66-A nrPDB Length = 337 Score = 42.5 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 41/263 (15%), Positives = 77/263 (29%), Gaps = 45/263 (17%) Query: 10 ILTAAAQGIGQAAALAFAREGA-------KVIATDI-----NESKLQELEKYPGIQTRVL 57 ++T A IG GA +VI D N + L ++ P ++ Sbjct: 4 LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHG 62 Query: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 D+ A E+ +D + + A H +D NV+ +++ + Sbjct: 63 DIRDAGL---LARELRGVDAIVHFAAESH----VDRSIAGASVFTETNVQGTQTLLQCAV 115 Query: 118 PKMLAQKSGNIINMS-----------SVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 G ++++S S S N Y+ +KA + ++ + Sbjct: 116 DA----GVGRVVHVSTDEVYGSIDSGSWTESSPLEPN-SPYAASKAGSDLVARAYHRTYG 170 Query: 167 QQ-GIR--CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEE-IAMLCV 222 I CN P L + + ++ + + Sbjct: 171 LDVRITRCCNNYGP-YQHPEKLIPLFVTNLLDGGTLPLYGDGANVREWVHTDDHCRGIAL 229 Query: 223 YLASDESAYVTGNPVIIDGGWSL 245 LA + G I GG L Sbjct: 230 VLAGGRA----GEIYHIGGGLEL 248 >3SXP-A nrPDB Length = 362 Score = 42.1 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 44/241 (18%), Positives = 80/241 (33%), Gaps = 40/241 (16%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREG--AKVIATDI----------NESKLQELEKYPG 51 L+ + I++T A +G A F AKV+ D S L + G Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 52 IQTRVL--DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSM 109 + V+ D+ + + D LF+ A D + + M N ++ Sbjct: 68 FKGEVIAADINNPLDLRRLEKL--HFDYLFHQAAVS------DTTMLNQELVMKTNYQAF 119 Query: 110 YLMIKAFLPKMLAQKSGNIINMSSVA----SSVKGVVNR-----CVYSTTKAAVIGLTKS 160 +++ K +I SS + VV + VY +K + S Sbjct: 120 LNLLEIA-----RSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMDEFVLS 174 Query: 161 VAADFIQQGIR-CNCVCPGTV---DTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEE 216 + D +Q G+R N P T S+ ++ + F ++ F E+ Sbjct: 175 HSNDNVQVGLRYFNVYGPREFYKEKTASMVLQLALGAMAFKEVKLFEFGEQLRDFVYIED 234 Query: 217 I 217 + Sbjct: 235 V 235 >2PZM-A nrPDB Length = 330 Score = 42.1 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 40/117 (34%), Gaps = 9/117 (7%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-LEKYPGIQTRVLDVTKKKQID 66 I++T A +G + +G +++ D + +E L G+ VT ++ Sbjct: 22 RILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGLSVIEGSVTDAGLLE 81 Query: 67 QFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQ 123 + + + V + A DW NV+ + KA + + Sbjct: 82 RAFDSFKPTHV-VHSAAAYKD-------PDDWAEDAATNVQGSINVAKAASKAGVKR 130 >1GY8-A nrPDB Length = 397 Score = 41.7 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 32/205 (15%), Positives = 65/205 (31%), Gaps = 52/205 (25%) Query: 8 VIILTAAAQGIGQAAALAFARE-GAKVIATD-------------INESKLQELEKYPG-- 51 +++ A IG A R+ V+ D E+ ++L++ G Sbjct: 4 RVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPK 63 Query: 52 -------IQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNL 104 V DV + ++ +D + ++ F+ G +D + Sbjct: 64 PPWADRYAALEVGDVRNEDFLNGVFTRHGPIDAVVHMCAFLAVGE----SVRDPLKYYDN 119 Query: 105 NVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNR-------------------C 145 NV + +++A ML K II S ++++ G Sbjct: 120 NVVGILRLLQA----MLLHKCDKIIF--SSSAAIFGNPTMGSVSTNAEPIDINAKKSPES 173 Query: 146 VYSTTKAAVIGLTKSVAADFIQQGI 170 Y +K + + A + +GI Sbjct: 174 PYGESKLIAERMIRDCAEAYGIKGI 198 >4J90-A nrPDB Length = 222 Score = 41.3 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 MGR+ K + + G + R G +V+A DINE K+ Y + + T Sbjct: 1 MGRIKNKQFAVIGLGR-FGGSICKELHRMGHEVLAVDINEEKVNAYASYA-THAVIANAT 58 Query: 61 KKKQI 65 ++ ++ Sbjct: 59 EENEL 63 >3SC6-A nrPDB Length = 287 Score = 41.3 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 54/164 (32%), Gaps = 36/164 (21%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 +I+T A +G+ E + D ++LD+T Q+ Q Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDK----------------KLLDITNISQVQQ 50 Query: 68 FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGN 127 E+ R ++ + A + +D EK+ D + +N + A +++ Sbjct: 51 VVQEI-RPHIIIHCAAYTK----VDQAEKERDLAYVINAIGARNV--AVASQLV---GAK 100 Query: 128 IINMSS----------VASSVKGVVNRCVYSTTKAAVIGLTKSV 161 ++ +S+ +Y +K A K + Sbjct: 101 LVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >4K28-A nrPDB Length = 269 Score = 40.6 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 36/91 (39%), Gaps = 9/91 (9%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREG-AKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 GK ++ G+G A A A A G A + D + +++ + + G L V+ + Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVSTQ- 181 Query: 64 QIDQFANEVERLDVLFNVAGFVHHGTVLDCE 94 + +E D L A V GT + Sbjct: 182 -----FSGLEDFD-LVANASPVGMGTRAELP 206 >4R1T-A nrPDB Length = 337 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 40/141 (28%), Gaps = 20/141 (14%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES-----KLQELEKYPGIQTR 55 M + G+V+ +T A I +G V T N L+ELE T Sbjct: 5 MRSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTL 64 Query: 56 VLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + D +F+ A V E V +I A Sbjct: 65 CK--ADLLDYQSLREAINGCDGVFHTASPVTDDPEQMVEPA---------VIGTKNVINA 113 Query: 116 FLPKMLAQKSGNIINMSSVAS 136 + ++ SS+ + Sbjct: 114 AAEANVR----RVVFTSSIGA 130 >5BUT-A nrPDB Length = 288 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 MGR+ K + + G + R G +V+A DINE K+ Y + + T Sbjct: 1 MGRIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNAYASYA-THAVIANAT 58 Query: 61 KKKQI 65 ++ ++ Sbjct: 59 EENEL 63 Score = 33.6 bits (76), Expect = 0.079, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 17 GIGQ---AAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 G+G+ + R G +V+A DINE K+ Y + + T++ ++ Sbjct: 155 GLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYA-THAVIANATEENEL 205 >2HMT-A nrPDB Length = 144 Score = 40.2 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 MGR+ K + + G + R G +V+A DINE K+ Y + + T Sbjct: 1 MGRIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNAYASYA-THAVIANAT 58 Query: 61 KKKQI 65 ++ ++ Sbjct: 59 EENEL 63 >4KDR-A nrPDB Length = 223 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK 61 G L GK ++ GI A + AREGA V D+ LQ + + +D + Sbjct: 59 GGLFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ 115 Query: 62 KKQIDQFANEVERLDVL 78 + + A + DV+ Sbjct: 116 ETVEEHAAKHAGQYDVV 132 >1GPJ-A nrPDB Length = 404 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 37/93 (39%), Gaps = 10/93 (10%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAK-VIATDINESKLQELEKYPGIQTRVLDV 59 +G L K +++ A + +G+ A + G + V+ + + EL + G + D Sbjct: 162 LGSLHDKTVLVVGAGE-MGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFD- 219 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLD 92 + + + R DV+ + H +D Sbjct: 220 -------ELVDHLARSDVVVSATAAPHPVIHVD 245 >2HUN-A nrPDB Length = 336 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 32/172 (18%), Positives = 66/172 (38%), Gaps = 29/172 (16%) Query: 10 ILTAAAQGIGQAAALAFAREG--AKVIATDI-----NESKLQELEKYPGIQTRVLDVTKK 62 ++T IG + +VI D N + L++LE P DV Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVKGDVADY 66 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK-------- 114 + + + ++D + ++A H + + + ++ NV Y +++ Sbjct: 67 ELVKELVR---KVDGVVHLAAESHVDRSIS-SPEIF---LHSNVIGTYTLLESIRRENPE 119 Query: 115 -AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAA----VIGLTKSV 161 F+ + G+I+ S + + + + YS TKAA V+G T++ Sbjct: 120 VRFVHVSTDEVYGDILK-GSFTENDRLMPS-SPYSATKAASDMLVLGWTRTY 169 >6ACF-A nrPDB Length = 367 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 33/93 (35%), Gaps = 13/93 (13%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L+GKV+ + + EGAK+I TDIN+ + + G + Sbjct: 171 LEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAV-----DPN 224 Query: 64 QIDQFANEVERLDVLFNVA--GFVHHGTVLDCE 94 I D+ A G ++ T+ + Sbjct: 225 DIYGV-----ECDIFAPCALGGIINDQTIPQLK 252 >3OND-A nrPDB Length = 488 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 35/96 (36%), Gaps = 11/96 (11%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 GKV ++ +G+ A A + GA+VI T+I+ + + DV + Sbjct: 264 AGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLEDVVSEAD 322 Query: 65 IDQFANEVERLDVLF--------NVAGFVHHGTVLD 92 I F D++ N A + G + Sbjct: 323 I--FVTTTGNKDIIMLDHMKKMKNNAIVCNIGHFDN 356 >6GCS-E nrPDB Length = 375 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 19/122 (15%), Positives = 44/122 (36%), Gaps = 14/122 (11%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINE---SKLQELEKYPGIQTRVLDVTK 61 G + A +G A+ G V+ E L+ + +D+ Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREEMAKRHLKVTGDLGVVNFLEMDLRN 111 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 + ID+ D++ N+ G + E K++++ +++V + +A + Sbjct: 112 LESIDEAVRHS---DIVVNLIG-------REYETKNFNY-YDVHVEGARRIAEAVKKHNI 160 Query: 122 AQ 123 A+ Sbjct: 161 AR 162 >1WVG-A nrPDB Length = 359 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 24/166 (14%), Positives = 60/166 (36%), Gaps = 29/166 (17%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGI----QTRVLDVT 60 GK + +T G +L GA V ++ + L + + ++ + D+ Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHIGDIR 67 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 +++ E + +++F++A ++ + + + NV +++ Sbjct: 68 DFEKLRSSIAEFKP-EIVFHMAA----QPLVRLSYEQPIKTYSTNVMGTVHLLETV---- 118 Query: 121 LAQKSGNI---INMSS---------VASSVKGVV--NRCVYSTTKA 152 ++ GNI +N++S V + YS +K Sbjct: 119 --KQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >4KDC-A nrPDB Length = 246 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK 61 G L GK ++ GI A + AREGA V D+ LQ + + +D + Sbjct: 59 GGLFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ 115 Query: 62 KKQIDQFANEVERLDVL 78 + + A + DV+ Sbjct: 116 ETVEEHAAKHAGQYDVV 132 >1OC2-A nrPDB Length = 348 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 34/195 (17%), Positives = 62/195 (31%), Gaps = 38/195 (19%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDIN----ESKLQELEKYPG--IQTRVLDVT 60 K II+T A IG V T ++ LE G ++ V D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVH-HGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 + +D+ A + D + + A H ++ D ++ N Y +++A Sbjct: 65 DAELVDKLAAKA---DAIVHYAAESHNDNSLNDPSPF-----IHTNFIGTYTLLEAARKY 116 Query: 120 MLAQKSGNIINMSSVASSVK---GVVNR-----------------CVYSTTKAAVIGLTK 159 + ++ V + + YS+TKAA + K Sbjct: 117 DIRFHH---VSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASDLIVK 173 Query: 160 SVAADFIQQGIRCNC 174 + F + NC Sbjct: 174 AWVRSFGVKATISNC 188 >4KTT-E nrPDB Length = 327 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 17/128 (13%), Positives = 43/128 (33%), Gaps = 19/128 (14%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 + +++T A +G+A F + + ++ + +++ + Sbjct: 21 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK---------FEQVNLLDSNAV 71 Query: 66 DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS 125 ++ + V+ + A V + D + LNV + + K A Sbjct: 72 HHIIHDFQP-HVIVHCAAERRPDVVENQP----DAASQLNVDASGNLAKEA-----AAVG 121 Query: 126 GNIINMSS 133 +I +SS Sbjct: 122 AFLIYISS 129 >3NJ4-A nrPDB Length = 435 Score = 39.4 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 47/145 (32%), Gaps = 15/145 (10%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 GKV ++ +G+ A A GA+VI T+I+ + G + +D ++ Sbjct: 215 AGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQ-AAMEGYEVTTMDEACQEG 272 Query: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNL-----NVRSMYLMIKAFLPK 119 + F +D++ + C +D +++ N + Sbjct: 273 -NIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 331 Query: 120 MLAQKS-------GNIINMSSVASS 137 L G ++N+ Sbjct: 332 RLKNGRRIILLAEGRLVNLGCAMGH 356 >1BXK-A nrPDB Length = 355 Score = 39.4 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 27/178 (15%), Positives = 59/178 (33%), Gaps = 28/178 (15%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAK-VIATDI-----NESKLQELEKYPGIQTRVLDVT 60 + I++T A IG A E + V+ D N L + + +D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 + ++ + E + D + ++A H +D + N+ Y +++A Sbjct: 62 DRAELARVFTEHQP-DCVMHLAAESHVDRSIDGPA----AFIETNIVGTYTLLEAARAYW 116 Query: 121 LA-----------------QKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSV 161 A + G++ + + YS +KA+ L ++ Sbjct: 117 NALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAW 174 >4J2O-A nrPDB Length = 363 Score = 39.4 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 19/155 (12%), Positives = 50/155 (32%), Gaps = 17/155 (10%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAK-VIATDINESKLQELEKYPGIQTRVLDVTKK 62 KV+++T G A F K + +E K ++ K + Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYIGDV 80 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD--FSMNLNVRSMYLMIKAFLPKM 120 + + N +D +++ A + ++ ++ NV +++A + Sbjct: 81 RDYNSILNATRGVDYIYHAAA------LKQVPSCEFHPMEAVKTNVLGTENVLEAAIQNH 134 Query: 121 LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVI 155 + ++ +S+ + +KA + Sbjct: 135 VK----RVVCLSTDKAVYP----INAMGISKAMME 161 >3VPX-A nrPDB Length = 364 Score = 39.0 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD 58 L GK + + + A EGAK+I TDINE +Q G ++ Sbjct: 171 LAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGIN 224 >1KEU-A nrPDB Length = 361 Score = 38.6 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 27/197 (13%), Positives = 55/197 (27%), Gaps = 36/197 (18%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIAT------DINESKLQELEKYPGIQTRVLDVTKK 62 I++T A IG A + + N L ++ + D+ Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDS 62 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLA 122 +I + + + D + ++A H + + N+ Y +++ A Sbjct: 63 AEITRIFEQYQP-DAVMHLAAESHVDRSITGPA----AFIETNIVGTYALLEVARKYWSA 117 Query: 123 QKSGNIINM---------------------SSVA----SSVKGVVNRCVYSTTKAAVIGL 157 N +SV + YS +KA+ L Sbjct: 118 LGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHL 177 Query: 158 TKSVAADFIQQGIRCNC 174 ++ + I NC Sbjct: 178 VRAWRRTYGLPTIVTNC 194 >2Z95-A nrPDB Length = 345 Score = 38.6 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 41/104 (39%), Gaps = 13/104 (12%) Query: 4 LDGKVIILTAAAQGI-GQAAALAFAREGAKVIATDINES-----KLQELEKYPGIQTRVL 57 + GK ++T +G G A +G +V D +L+EL ++ + Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHM 59 Query: 58 DVTKKKQIDQFANEVERLDVLFNVA-----GFVHHGTVLDCEEK 96 D+ + I + +V+ D ++N+A G +L E Sbjct: 60 DLLEFSNIIRTIEKVQP-DEVYNLAAQSFVGVSFEQPILTAEVD 102 >1LU9-A nrPDB Length = 287 Score = 38.6 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK 61 G + GK ++ A +G +A A EGA+V+ K Q + +V +VT Sbjct: 115 GSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKV-NVTA 173 Query: 62 KKQIDQFANE 71 + D + Sbjct: 174 AETADDASRA 183 >3HFS-A nrPDB Length = 338 Score = 38.2 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 47/137 (34%), Gaps = 17/137 (12%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ------ELEKYPGIQTRVLDV 59 K + + ++G V T + + EL++ ++ D+ Sbjct: 9 KKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADL 68 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 T + + + D +F+VA V E + + ++ + ++KA Sbjct: 69 TDELSFEA---PIAGCDFVFHVA-----TPVHFASEDPENDMIKPAIQGVVNVMKACTR- 119 Query: 120 MLAQKSGNIINMSSVAS 136 A+ +I SS A+ Sbjct: 120 --AKSVKRVILTSSAAA 134 >5JXW-A nrPDB Length = 498 Score = 38.2 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 11/97 (11%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L GK I++ + +G+ A + GA+VI T+I+ + + + DV + Sbjct: 269 LAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEA 327 Query: 64 QIDQFANEVERLDVLFN--------VAGFVHHGTVLD 92 I F DV+ A + G D Sbjct: 328 DI--FITATGNKDVITVEHMRKMKENAYIANIGHFDD 362 >2C54-A nrPDB Length = 379 Score = 37.9 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 38/106 (35%), Gaps = 7/106 (6%) Query: 11 LTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFAN 70 +T A I A EG VIA+D + E + ++D+ ++ Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDW-KKNEHMTEDMFCDEFHLVDLR---VMENCLK 89 Query: 71 EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 E +D +FN+A + + M N + MI+A Sbjct: 90 VTEGVDHVFNLAADMGGMGFIQSNHSV---IMYNNTMISFNMIEAA 132 >6GBN-A nrPDB Length = 438 Score = 37.5 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 36/80 (45%), Gaps = 13/80 (16%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 + GKV ++ +G+ +A + GA+VI T E++ +Q + Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVT--------EIDPICALQAAM----DGY 263 Query: 64 QIDQFANEVERLDVLFNVAG 83 ++ + A+ V+R D++ G Sbjct: 264 EVKKMADAVKRADIVVTATG 283 >4WPG-A nrPDB Length = 289 Score = 37.5 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 16/111 (14%), Positives = 39/111 (35%), Gaps = 20/111 (18%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQF 68 I++T + +G G +A D+ E +D+T + +++ Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVDVAE----------------MDITNEDKVEAV 50 Query: 69 ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 +V+ ++++ A + D + + +NV + KA Sbjct: 51 FAQVKPT-LVYHCAAYTAVDAAEDEGKALNE---AINVTGSENIAKACGKY 97 >5N2I-A nrPDB Length = 232 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG 51 + G I + G+ A FA G +VI + + Q + G Sbjct: 17 VSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELG 64 >1O89-A nrPDB Length = 345 Score = 36.3 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD 58 I++T A+ G+G A + G +V+A ES + L+ + D Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRD 220 >6G2J-P nrPDB Length = 377 Score = 35.9 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 40/118 (33%), Gaps = 14/118 (11%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES----KLQELEKYPGIQTRVLDV 59 + G V + A +G+ R G++VI + L+ + + D Sbjct: 51 VSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQLTFLEWDA 110 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNV-RSMYLMIKAF 116 K I + +V+ N+ G + D++ +N+ R++ K Sbjct: 111 RDKDSIRKAVQHS---NVVINLIGREW-----ETRNFDFEDVF-VNIPRAIAQASKEA 159 >4EUF-A nrPDB Length = 418 Score = 35.9 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 23/96 (23%) Query: 7 KVIILTAAAQGIGQA--AALAFAREGAKVI-------ATDINESKL--------QELEKY 49 K +++ A+ G G A ++AF A I ATD +E K Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 50 PG------IQTRVLDVTKKKQIDQFANEVERLDVLF 79 G I+ + TK K I +E ++D+ Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >3PVZ-A nrPDB Length = 399 Score = 35.2 bits (80), Expect = 0.025, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 59/177 (33%), Gaps = 21/177 (11%) Query: 10 ILTAAAQGIGQAAALA-FAREGAKVIATDINE----SKLQELEKYPG-----IQTRVLDV 59 ++ A IGQA F R K+ DI+E ++++ G QT LD+ Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFALDI 98 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 + D F + D + N++ H + + + +++NV + I+ + Sbjct: 99 GSIE-YDAFIKADGQYDYVLNLSALKHVRS--EKDPFTLMRMIDVNVFNTDKTIQQSIDA 155 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 + V++ + +K + + + R V Sbjct: 156 GAKKYF-------CVSTDKAANP-VNMMGASKRIMEMFLMRKSEEIAISTARFANVA 204 >6DEB-A nrPDB Length = 285 Score = 35.2 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 36/100 (36%), Gaps = 9/100 (9%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD--VTK 61 L+GK ++ A+ +G+ A GA V I K + TR D + Sbjct: 158 LEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIK-------TKDLSLYTRQADLIIVA 210 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFS 101 ++ +++ + V+ G + + D++ Sbjct: 211 AGCVNLLRSDMVKEGVIVVDVGINRLESGKIVGDVDFEEV 250 >5INT-A nrPDB Length = 220 Score = 35.2 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 36/102 (35%), Gaps = 21/102 (20%) Query: 4 LDGKVIILTAA---------------AQG-IGQAAALAFAREGAKVIATDINESKLQELE 47 L GK I++TA + G +G A A GA+VI S L Sbjct: 4 LQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILV----SGPTALN 59 Query: 48 KYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGT 89 + T ++ + + ++ + +DV+ A + Sbjct: 60 PPLHVTTVQVE-SAQDMLEAVIQHYQNVDVVIKTAAVADYRP 100 >4A10-A nrPDB Length = 447 Score = 34.8 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 22/152 (14%), Positives = 55/152 (36%), Gaps = 33/152 (21%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREG----AKVIATDINESKLQEL-------EKYPGIQ 53 G ++++ A+ G+G + A+ F + G V+++ E+ ++ L GI Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 54 TRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 + D +++ + ++ +L + AG + Sbjct: 279 DDIAD--DPRRVVETGRKLAKL--VVEKAGREPDIVFEHTGRVTF--------------- 319 Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRC 145 L ++A++ G ++ S + + NR Sbjct: 320 --GLSVIVARRGGTVVTCGSSSGYLHTFDNRY 349 >3WMX-A nrPDB Length = 358 Score = 34.8 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 39/196 (19%), Positives = 66/196 (33%), Gaps = 35/196 (17%) Query: 5 DGK-VIILTAAAQGIGQAAALAFARE-G-AKVIATDINESKLQELEKYPGIQTRVLDVTK 61 GK I++ A IG ALA A G VI +D+ + ++ + +L+ T Sbjct: 23 AGKPKILIVGANGQIGSELALALAERYGRTNVITSDVVPTG-----RHVHLTHEMLNATD 77 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKML 121 + ++ V A G EK ++ NLN+ S+ +++ Sbjct: 78 RGELATVVERHGITQVYLLAAALSATG------EKAPQWAWNLNMTSLLNVLELA----R 127 Query: 122 AQKSGNIINMSSVASSVKGVVN-----------RCVYSTTKAAVIGLTKSVAADFIQQGI 170 + SS+A+ VY +K A G + G+ Sbjct: 128 QTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWCRWY---HANHGV 184 Query: 171 RCNCVC-PGTV--DTP 183 V PG + TP Sbjct: 185 DVRSVRYPGLISHKTP 200 >4EJ6-A nrPDB Length = 370 Score = 34.4 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 27/85 (31%), Gaps = 6/85 (7%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 G + + IG GA + ++ + L + G V D + Sbjct: 182 AGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATV-DPSAGDV 239 Query: 65 IDQFANEV----ERLDVLFNVAGFV 85 ++ A V +DV+ AG Sbjct: 240 VEAIAGPVGLVPGGVDVVIECAGVA 264 >2EER-A nrPDB Length = 347 Score = 34.4 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Query: 7 KVIILTAAAQGIGQ-AAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 K +++ A G+G A +A A GA +I D+ E L+ ++ V++ + + + Sbjct: 172 KTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAG--ADYVINASSQDPV 229 Query: 66 DQF 68 + Sbjct: 230 SEI 232 >2C20-A nrPDB Length = 330 Score = 34.4 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 52/161 (32%), Gaps = 24/161 (14%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQF 68 I++ A IG A EG V+ D N E G + D+ K + Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVD-NLQTGHEDAITEGAKFYNGDLRDKAFLRDV 62 Query: 69 ANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNI 128 + E ++ + + A +++ + N NV L + + + K Sbjct: 63 FTQ-ENIEAVMHFAA----DSLVGVSMEKPLQYYNNNVYGA-LCLLEVMDEFKVDKF--- 113 Query: 129 INMSSVASSVKGVVN------------RCVYSTTKAAVIGL 157 + S ++ G V+ Y TK A+ + Sbjct: 114 --IFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKM 152 >6ACQ-A nrPDB Length = 302 Score = 34.4 bits (78), Expect = 0.045, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE 45 K + + A +G A AFA +G +V+ DI + + Sbjct: 22 KKVCVIGAGT-MGSGIAQAFAAKGFEVVLRDIKDEFVDR 59 >3DFZ-A nrPDB Length = 223 Score = 34.4 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 41/105 (39%), Gaps = 16/105 (15%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKV------IATDINESKLQELEKYPGIQT 54 M L G+ +++ I F +EGA + ++ +INE + + + + Sbjct: 26 MLDLKGRSVLVVGGGT-IATRRIKGFLQEGAAITVVAPTVSAEINEWEAKGQLRVKRKKV 84 Query: 55 RVLDV---------TKKKQIDQFANEVERLDVLFNVAGFVHHGTV 90 D+ T + +++F + + D L N+A G + Sbjct: 85 GEEDLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMASSFSDGNI 129 >1E3J-A nrPDB Length = 352 Score = 34.4 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 39/82 (47%), Gaps = 5/82 (6%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ- 64 G +++ A IG + LA GA V+ T + +L+ + T V+D K+++ Sbjct: 169 GTTVLVIGAGP-IGLVSVLAAKAYGAFVVCTARSPRRLEVAKNCGADVTLVVDPAKEEES 227 Query: 65 --IDQFANEVERL-DVLFNVAG 83 I++ + + L +V + +G Sbjct: 228 SIIERIRSAIGDLPNVTIDCSG 249 >4KUG-A nrPDB Length = 290 Score = 34.4 bits (78), Expect = 0.053, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE 45 K + + A +G AFA +G +VI DI E + Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEEFVDR 39 >4YUC-A nrPDB Length = 335 Score = 34.0 bits (77), Expect = 0.057, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 68/204 (33%), Gaps = 38/204 (18%) Query: 30 GAKVIATDINESKL--QELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAG---- 83 G V I E + E + G + K+ + ++E +D++ N +G Sbjct: 39 GWCVEKQGIRERRWVKDETASFMGAEAA------KEAVRDAGLKLEDIDLIINASGSPEQ 92 Query: 84 -FVHHGTVLDCEEKDWDF---SMNLNVR--SMYLMIKAFLPKMLAQKSGNIIN----MSS 133 G ++ E S+ +N S ++ + + ++ I+ +SS Sbjct: 93 AVPDGGPLVQRELGLGRSGVPSITVNASCLSFFVALDVAANYLNMRRYKRILIVSSDISS 152 Query: 134 VASSVKGVVNRCVYS-TTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQAR 192 VA + N ++ AAV+ L + ++ +C+ V T Sbjct: 153 VALDFRKPENFTLFGDAAAAAVVTL-----PEPGEK----SCIHASQVRT------YGYG 197 Query: 193 GNPEEARNDFLKRQKTGRFATAEE 216 +R G+ T E+ Sbjct: 198 AEFSMVPGGGSRRHPNGKNTTPED 221 >4EJ0-A nrPDB Length = 342 Score = 34.0 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 45/119 (37%), Gaps = 14/119 (11%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT-RVLDVTKKKQID 66 +I+T AA IG A G I N ++ + + + LD T + ++ Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKT--EFVE 71 Query: 67 QFAN-EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124 +FA + ++ H G D E D + M+ N + +A L LAQ Sbjct: 72 RFARGDFGKVR------AVFHEGACSDTMETDGRYMMDNN----FRYSRAVLDACLAQG 120 >3N58-A nrPDB Length = 464 Score = 34.0 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 + GKV ++ +G+ +A + A GA+V T+++ + + D Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTA 303 Query: 64 QI 65 I Sbjct: 304 DI 305 >4WLE-A nrPDB Length = 340 Score = 33.6 bits (76), Expect = 0.069, Method: Composition-based stats. Identities = 35/218 (16%), Positives = 67/218 (30%), Gaps = 31/218 (14%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI- 65 KV +L A+ GIGQ +L ++ L ++ PG+ + + K + Sbjct: 28 KVAVL-GASGGIGQPLSLLLKNSPL------VSRLTLYDIAHTPGVAADLSHIETKAAVK 80 Query: 66 -----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKM 120 +Q + ++ DV+ AG + D N N + + A Sbjct: 81 GYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNATIVATLTAACAQHC 134 Query: 121 LAQKSGNIIN--MSSVASSVKGVVNRCVYSTTK-AAVIGL----TKSVAADF-----IQQ 168 I N S++ + + VY+ K V L + A+ + Sbjct: 135 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARV 194 Query: 169 GIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQ 206 + G P + + P++ R Sbjct: 195 NVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRI 232 >2BKA-A nrPDB Length = 242 Score = 33.6 bits (76), Expect = 0.083, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 34/86 (39%), Gaps = 6/86 (6%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREG--AKVIATDINESKLQELEKYPGIQTRVLDVT 60 R+ K + + A+ G+ +G +KV + E E Y + V+D Sbjct: 15 RMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDE-EAYKNVNQEVVDF- 72 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVH 86 +++D +A+ + DV F G Sbjct: 73 --EKLDDYASAFQGHDVGFCCLGTTR 96 >2HK7-A nrPDB Length = 269 Score = 33.6 bits (76), Expect = 0.087, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 35/77 (45%), Gaps = 11/77 (14%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 + K I++ A G +A A +EGAKV + + K +L + ++ V + Sbjct: 121 VKEKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEV----VNSPE 175 Query: 64 QIDQFANEVERLDVLFN 80 ++ ++++ V+ N Sbjct: 176 EV------IDKVQVIVN 186 >5F5N-A nrPDB Length = 289 Score = 33.2 bits (75), Expect = 0.095, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 22/71 (30%), Gaps = 1/71 (1%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK-LQELEKYPGIQTRVLDVTKKKQ 64 + I++T A G A A G V A + G+ D+ + Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQAS 60 Query: 65 IDQFANEVERL 75 + +V + Sbjct: 61 LRAAMADVHGV 71 >1RPN-A nrPDB Length = 335 Score = 33.2 bits (75), Expect = 0.096, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 26/68 (38%), Gaps = 5/68 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKV---IATDINES--KLQELEKYPGIQTRVLDVTK 61 + ++T G A +G +V +A +++ +L+EL IQ D+ Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDGDMAD 74 Query: 62 KKQIDQFA 69 + + Sbjct: 75 ACSVQRAV 82 >3H9U-A nrPDB Length = 436 Score = 33.2 bits (75), Expect = 0.097, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 28/74 (37%), Gaps = 3/74 (4%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 GK + +G+ A A GA+V+ T+++ + V DV ++ Sbjct: 210 AGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEEAH 268 Query: 65 IDQFANEVERLDVL 78 I F D++ Sbjct: 269 I--FVTTTGNDDII 280 >4XRR-A nrPDB Length = 456 Score = 33.2 bits (75), Expect = 0.097, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 36/95 (37%), Gaps = 8/95 (8%) Query: 10 ILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK------YPGIQTRVLDV--TK 61 ++ A A +G A+ A GA+V+A D + + +L PG+ V D+ T Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAATG 77 Query: 62 KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEK 96 + + V DV+ G ++ Sbjct: 78 RLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQ 112 >2GAS-A nrPDB Length = 307 Score = 33.2 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 28/81 (34%), Gaps = 6/81 (7%) Query: 9 IILTAAAQGIGQAAALAFAREG---AKVI---ATDINESKLQELEKYPGIQTRVLDVTKK 62 I++ IG+ A + G ++ T N +EL +L Sbjct: 5 ILILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLGVILLEGDI 64 Query: 63 KQIDQFANEVERLDVLFNVAG 83 + ++++D++ AG Sbjct: 65 NDHETLVKAIKQVDIVICAAG 85 >4J6F-A nrPDB Length = 382 Score = 33.2 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 11/61 (18%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 G+ +++T A+ G+G A GA IA PG + +LD+ + Sbjct: 206 AGETVLVTGASGGVGSAIIQLARARGAVPIAV-----------AGPGKEAAMLDIGAQAV 254 Query: 65 I 65 + Sbjct: 255 V 255 >5EGS-A nrPDB Length = 376 Score = 32.9 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 13/79 (16%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGA-KVIATDINE--SKLQELEKYPGIQTR----- 55 L GK ++ A GI ++ A+ GA +V A + + + +E+ ++ G++ R Sbjct: 82 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLP 138 Query: 56 --VLDVTKKKQIDQFANEV 72 V V +Q+D +E Sbjct: 139 GPVETVELPEQVDAIVSEW 157 >2GGS-A nrPDB Length = 273 Score = 32.9 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 47/106 (44%), Gaps = 15/106 (14%) Query: 10 ILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFA 69 ++T A+ +G + + +VI N S++Q LD+T +++ F Sbjct: 4 LITGASGQLGIELSRLLSER-HEVIKVY-NSSEIQ--------GGYKLDLTDFPRLEDFI 53 Query: 70 NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKA 115 + +R DV+ N A +D E + + + +N ++ +++A Sbjct: 54 IK-KRPDVIINAAAMTD----VDKCEIEKEKAYKINAEAVRHIVRA 94 >2EXX-A nrPDB Length = 306 Score = 32.9 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREG---AKVIATDINESKLQELEKYPGIQTRVLDVT 60 +D K++++ G + A +G +V+ + + +EL + G + D Sbjct: 9 VDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKEL-RLQGAEVVQGDQD 67 Query: 61 KK 62 + Sbjct: 68 DQ 69 >4PZE-A nrPDB Length = 284 Score = 32.9 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 76/225 (33%), Gaps = 29/225 (12%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE----LEKYPGIQTRVLDVTKK 62 + + + A +G A A A G V+ DI+++ +Q+ + + +T+ Sbjct: 4 RTVGIVGAGT-MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 63 KQIDQFAN--------EVERLDVLFNVAGFVHHGTVLDCEEKD----WDFSMNLNVRSMY 110 + A +++ D++ A + V ++ D + + N S Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSS-I 121 Query: 111 LMIKAFLPKMLAQK--SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQ 168 + K A + + N V + V+ + TT AAV L+K + Sbjct: 122 SITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSK----QLGKY 177 Query: 169 GIRCNCVCPGT----VDTPSLQERIQARGNPEEARNDFLKRQKTG 209 I PG + P + E G + + + K G Sbjct: 178 PITVKN-SPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGMKLG 221 >3R0Q-C nrPDB Length = 376 Score = 32.5 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 32/80 (40%), Gaps = 13/80 (16%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGA-KVIATDIN--ESKLQELEKYPG-------I 52 +GK ++ GI A+ A+ GA KV A + + L K I Sbjct: 61 HFEGKTVLDVGTGSGI---LAIWSAQAGARKVYAVEATKMADHARALVKANNLDHIVEVI 117 Query: 53 QTRVLDVTKKKQIDQFANEV 72 + V D++ +++D +E Sbjct: 118 EGSVEDISLPEKVDVIISEW 137 >2VN8-A nrPDB Length = 375 Score = 32.5 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 40/110 (36%), Gaps = 9/110 (8%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK--K 62 GK +++ A+ G+G A A V T + EL + G DV Sbjct: 183 TGKRVLILGASGGVGTFAIQVMKAWDAHV--TAVCSQDASELVRKLGAD----DVIDYKS 236 Query: 63 KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 +++ ++ D + + G D K W + + + + +L+ Sbjct: 237 GSVEEQLKSLKPFDFILDNVGGSTETWAPDF-LKKWSGATYVTLVTPFLL 285 >4N18-A nrPDB Length = 332 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 13/63 (20%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDV 77 IG A AR G +V +E +L + Y G ++ +D F + LD Sbjct: 167 IGGYIADQLARLGYRVSGWSRSEKQLAGVTCYRG----------EEALDHF---LGSLDG 213 Query: 78 LFN 80 L N Sbjct: 214 LIN 216 >1MLD-A nrPDB Length = 314 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 41/119 (34%), Gaps = 19/119 (15%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI- 65 KV +L A+ GIGQ +L ++ L ++ PG+ + + + + Sbjct: 2 KVAVL-GASGGIGQPLSLLLKNSPL------VSRLTLYDIAHTPGVAADLSHIETRATVK 54 Query: 66 -----DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 +Q + ++ DV+ AG + D N N + + A Sbjct: 55 GYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNATIVATLTAACAQH 107 >5M65-A nrPDB Length = 479 Score = 32.5 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 30/75 (40%), Gaps = 3/75 (4%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L GKV ++ +G+ +A + + G +V+ ++++ + + D + Sbjct: 258 LSGKVAMVAGFGD-VGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRA 316 Query: 64 QIDQFANEVERLDVL 78 I F D++ Sbjct: 317 DI--FVTATGNKDII 329 >7REQ-A nrPDB Length = 727 Score = 32.1 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 32/92 (34%), Gaps = 9/92 (9%) Query: 13 AAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK--------Q 64 +G + A A+A G V + ++ + + V+ V+ Sbjct: 608 GHDRGQ-KVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPA 666 Query: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEK 96 + + +++ R D+L V G + + + Sbjct: 667 LRKELDKLGRPDILITVGGVIPEQDFDELRKD 698 >3LK7-A nrPDB Length = 451 Score = 32.1 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATD 37 + K +++ A+ G+AAA A+ GA V D Sbjct: 7 FENKKVLVLGLARS-GEAAARLLAKLGAIVTVND 39 >1F3L-A nrPDB Length = 321 Score = 32.1 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGA-KVIATDINESKLQELEKYPGIQTRVLDVTKK 62 KV++ GI A A+ GA KVIA D +E Q ++ + V K Sbjct: 44 FKDKVVLDVGCGTGILSMFA---AKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIK 100 Query: 63 KQIDQFANEVERLDVLF 79 +I++ + VE++DV+ Sbjct: 101 GKIEEVSLPVEKVDVII 117 >4BKP-A nrPDB Length = 336 Score = 32.1 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 16/108 (14%), Positives = 38/108 (35%), Gaps = 15/108 (13%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 I++T + +G+A +GA + D + ++ D+T Q Sbjct: 24 RILVTGGSGLVGKAI-QKVVADGAGLPGEDWV-----------FVSSKDADLTDTAQTRA 71 Query: 68 FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLN---VRSMYLM 112 +V+ V+ A + W ++++N + S + + Sbjct: 72 LFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 119 >3PEF-A nrPDB Length = 287 Score = 32.1 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 27/92 (29%), Gaps = 14/92 (15%) Query: 17 GI-GQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV-------LDVTKKKQIDQF 68 GI G A A + G V + + K +EL + VT D Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAMLADPA 69 Query: 69 ANE---VERLDVLFNVAGFVHHGTVLDCEEKD 97 A E + VL G +D D Sbjct: 70 AAEEVCFGKHGVL---EGIGEGRGYVDMSTVD 98 >3F6S-A nrPDB Length = 148 Score = 31.7 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 27/79 (34%), Gaps = 10/79 (12%) Query: 7 KVIILTAAAQGIGQAAALAF----AREGAKVIATDINESKLQELEKYPGIQTRVL----- 57 KV+I+ ++ G ++ A A G +V + ++ + L Sbjct: 3 KVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLADGYDAVLFGCSAWGM 62 Query: 58 -DVTKKKQIDQFANEVERL 75 D+ + E +R+ Sbjct: 63 EDLEMQDDFLSLFEEFDRI 81 >6CU3-A nrPDB Length = 336 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIA----TDINESKLQELEKYPGIQTRVLD 58 KV++ GI L A+ GAK + +DI + Q + L Sbjct: 49 LFKDKVVLDIGCGTGI---LCLFAAKAGAKRVIGIDMSDIIDKARQIVSDNGYSHVIELI 105 Query: 59 VTKKKQIDQFANEVERLDVLF 79 K + I Q +E++D++ Sbjct: 106 KGKVEDIAQLPFGIEKVDIII 126 >5GXF-A nrPDB Length = 330 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 18/50 (36%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD 58 +++T AA G+G A A G +V A L Q D Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGATQIVARD 202 >3RI6-A nrPDB Length = 430 Score = 31.7 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 12/79 (15%) Query: 12 TAAAQ--GIGQAAA------LAFAREGAKVIATDI----NESKLQELEKYPGIQTRVLDV 59 T A +G A L AR G V+ TD S Q+ GI+ R +DV Sbjct: 95 TGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFVDV 154 Query: 60 TKKKQIDQFANEVERLDVL 78 ++ +E +L L Sbjct: 155 MDSLAVEHACDETTKLLFL 173 >3DMF-A nrPDB Length = 381 Score = 31.7 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 31/78 (39%), Gaps = 4/78 (5%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 + G+ ++ A G A L AR GA+V+ + + + + L+K Sbjct: 232 VRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQ-ALHS 287 Query: 64 QIDQFANEVERLDVLFNV 81 +D+ E R D++ Sbjct: 288 DVDEALTEEARFDIIVTN 305 >5GUP-L nrPDB Length = 377 Score = 31.3 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 45/153 (29%), Gaps = 22/153 (14%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES----KLQELEKYPGIQTRVLDV 59 + G V + A +G+ R G++VI E L+ + I + Sbjct: 51 VSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFMEWNG 110 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 K I + + G + + D++ + A Sbjct: 111 KDKDSIRKVVEH--------SNVVINLVGREWETKNFDFEDVF-------VKIPHAIAQV 155 Query: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKA 152 +I++S + + +K Y +KA Sbjct: 156 SKEAGVEKLIHISHLNADIKSP---SRYLRSKA 185 >3X2F-A nrPDB Length = 411 Score = 31.3 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE 45 + GK +++ G+ AL A GA+VI T+++ K E Sbjct: 194 LVAGKNVVVAGYGW-CGRGIALRAAGLGARVIVTEVDPVKAVE 235 >4A6N-B nrPDB Length = 398 Score = 31.3 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 15/46 (32%), Gaps = 1/46 (2%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL 46 M L K + + +G A + G V + + + + Sbjct: 21 MNLLSDKNVAIIGGGP-VGLTMAKLLQQNGIDVSVYERDNDREARI 65 >4E0B-A nrPDB Length = 313 Score = 31.3 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 39/104 (37%), Gaps = 16/104 (15%) Query: 7 KVIILTAAAQGIGQAAALAFAR---EGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 KV ++ AA GIGQA AL G+ + DI PG+ + + Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIAPVT-------PGVAADLSHIPTHV 56 Query: 64 QIDQFANE-----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSM 102 I +A E +E DV+ AG + + + + + Sbjct: 57 SIKGYAGEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGI 100 >5LV5-A nrPDB Length = 403 Score = 31.3 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 36/79 (45%), Gaps = 13/79 (16%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGA-KVIATDINE--SKLQELEKYPGIQTR----- 55 L GK ++ A GI ++ A+ GA +V A + + + +E+ + G++ R Sbjct: 109 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLP 165 Query: 56 --VLDVTKKKQIDQFANEV 72 V V +++D +E Sbjct: 166 GPVETVELPERVDAIVSEW 184 >6C55-A nrPDB Length = 340 Score = 31.3 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 19/62 (30%), Gaps = 1/62 (1%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L GK I + G A A G V+ + ++ V + K+ Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQA 73 Query: 64 QI 65 + Sbjct: 74 DV 75 >2Q4B-A nrPDB Length = 253 Score = 31.3 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 25/73 (34%), Gaps = 5/73 (6%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL-DVTKKKQID 66 +++T A+ GQ +EG+ Q EK G + D+T I+ Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGSDKFVAKGLVRSAQGKEKIGGEADVFIGDITDADSIN 64 Query: 67 QFANEVERLDVLF 79 +D L Sbjct: 65 PAFQ---GIDALV 74 >2RIR-A nrPDB Length = 300 Score = 31.3 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 24/67 (35%), Gaps = 12/67 (17%) Query: 17 GIGQA---AALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVE 73 G+G+ A FA GA V + + L + + + D+ V+ Sbjct: 164 GLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHT---------DELKEHVK 214 Query: 74 RLDVLFN 80 +D+ N Sbjct: 215 DIDICIN 221 >2X86-A nrPDB Length = 357 Score = 30.9 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 31/100 (31%), Gaps = 7/100 (7%) Query: 7 KVIILTAAAQGIGQAAALAFAREGA-KVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 ++II+T A IG A +G ++ D + + + +D Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQ 106 Query: 66 DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105 E ++ H G E D + M+ N Sbjct: 107 IMAGEEFGDVE------AIFHEGACSSTTEWDGKYMMDNN 140 >3G1U-A nrPDB Length = 437 Score = 30.9 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 26/74 (35%), Gaps = 3/74 (4%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 GK + +G+ A A GA+V+ T+++ + V DV Sbjct: 211 AGKTCCVCGYGD-VGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVALVEDVMADAH 269 Query: 65 IDQFANEVERLDVL 78 I F D++ Sbjct: 270 I--FVTTTGNDDII 281 >2WEK-A nrPDB Length = 341 Score = 30.9 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 24/49 (48%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYP 50 G +GK +++TAAA G GQ A + VI T ++ K L+ Sbjct: 139 GLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLG 187 >1YB5-A nrPDB Length = 351 Score = 30.9 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 G+ +++ A+ G+G AA G K++ T E + + + + V + + Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHE--VFNHREVNY 227 Query: 65 IDQFANEVE--RLDVLF 79 ID+ V +D++ Sbjct: 228 IDKIKKYVGEKGIDIII 244 >5ENV-A nrPDB Length = 347 Score = 30.9 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFARE-GAKVIATDINESKLQELEKYPGIQTRVLDVT 60 + G + ++ AA G+G + A+ +A+ G +V+ D E K + G +D T Sbjct: 166 NLMAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGE--VFIDFT 222 Query: 61 KKKQIDQFA--NEVERLDVLFNV 81 K+K I + NV Sbjct: 223 KEKDIVGAVLKATDGGAHGVINV 245 >1V8B-A nrPDB Length = 479 Score = 30.5 bits (68), Expect = 0.60, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 40/100 (40%), Gaps = 19/100 (19%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINES-KLQELEKYPGIQTRVLDVTKKK 63 GK++++ +G+ A + GA+V T+I+ +Q + + + VT + Sbjct: 256 SGKIVVICGYGD-VGKGCASSMKGLGARVYITEIDPICAIQAVMEGFNV------VTLDE 308 Query: 64 QIDQ---FANEVERLDV--------LFNVAGFVHHGTVLD 92 +D+ F +DV + N A + G D Sbjct: 309 IVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDD 348 >1EDZ-A nrPDB Length = 320 Score = 30.5 bits (68), Expect = 0.61, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN 39 RL GK I+ ++ +G+ A A +GA V + D+N Sbjct: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 >1EQ2-A nrPDB Length = 310 Score = 30.5 bits (68), Expect = 0.64, Method: Composition-based stats. Identities = 27/166 (16%), Positives = 45/166 (27%), Gaps = 26/166 (15%) Query: 9 IILTAAAQGIGQAAALAFAREGA-KVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 II+T A IG A +G ++ D + + + +D Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIM 61 Query: 68 FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK--- 124 E ++ H G E D + M+ N Y K L L ++ Sbjct: 62 AGEEFGDVE------AIFHEGACSSTTEWDGKYMMDNN----YQYSKELLHYCLEREIPF 111 Query: 125 ---------SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSV 161 G S S + VY +K + + Sbjct: 112 LYASSAATYGGR---TSDFIESREYEKPLNVYGYSKFLFDEYVRQI 154 >1ZCJ-A nrPDB Length = 463 Score = 30.5 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 19/32 (59%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEKY 49 +G+ A++FAR G V+A + + +L +K Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKKI 79 >6BI4-A nrPDB Length = 346 Score = 30.5 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 26/161 (16%), Positives = 58/161 (36%), Gaps = 21/161 (13%) Query: 8 VIILTAAAQGIGQAAALAFAR--EGAKVIATDI-----NESKLQELEKYPGIQTRVLDVT 60 I++T A IG + E K+I D N + ++ ++ +P ++ Sbjct: 26 NILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGEIQ 85 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF--LP 118 + ++ E + + V+ N A H +D ++ + NV +++ P Sbjct: 86 NGELLEHVIKERD-VQVIVNFAAESH----VDRSIENPIPFYDTNVIGTVTLLELVKKYP 140 Query: 119 KML------AQKSGNIINMSSVASSVKGVVNRCVYSTTKAA 153 + + G++ N YS++KA+ Sbjct: 141 HIKLVQVSTDEVYGSLGKTGRFTEETPLAPN-SPYSSSKAS 180 >4WEQ-A nrPDB Length = 341 Score = 30.5 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 24/62 (38%), Gaps = 14/62 (22%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDV 77 +GQ AA A G KVI ++ ++ +E Y +D F + R D Sbjct: 172 LGQDAARKLAAMGFKVIGWSRSKRVIEGVETY-----------DAAGLDAF---LGRTDF 217 Query: 78 LF 79 L Sbjct: 218 LV 219 >5YWN-A nrPDB Length = 334 Score = 30.5 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 50/132 (37%), Gaps = 12/132 (9%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPG--IQTRVLDVTKKK-QI 65 + ++ A + Q +G KV+ + +E K L+K G V+ V ++K Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYEVVKVLEQKGAF 64 Query: 66 DQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLN-VRSMYLMIKAFLPKMLAQK 124 D+ + + + + A T + + +N + + IK P++ Sbjct: 65 DEALKKHPEVTIFLHTA---SPVTFEVEDTEKEILIPAINGTKYVLQSIKDVAPQIT--- 118 Query: 125 SGNIINMSSVAS 136 ++ SSV + Sbjct: 119 --RVVYTSSVVA 128 >3BIC-A nrPDB Length = 762 Score = 30.2 bits (67), Expect = 0.80, Method: Composition-based stats. Identities = 15/106 (14%), Positives = 37/106 (34%), Gaps = 17/106 (16%) Query: 13 AAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ-----IDQ 67 +G + A FA G V + ++ + ++ + V+ + + Sbjct: 616 GHDRG-AKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPE 674 Query: 68 FANEV---ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMY 110 E+ R D+L G + +D++F + V +++ Sbjct: 675 LIKELNSLGRPDILVMCGGVIPP--------QDYEFLFEVGVSNVF 712 >2DFV-A nrPDB Length = 347 Score = 30.2 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 30/82 (36%), Gaps = 16/82 (19%) Query: 2 GRLDGKVIILTAAA--QGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR---- 55 G + GK +++T A +G A A A GA + +EL K G Sbjct: 163 GPISGKSVLITGAGPLGLLGIAVAKA---SGAYPVIVSEPSDFRRELAKKVGADYVINPF 219 Query: 56 -------VLDVTKKKQIDQFAN 70 V+D+T +D F Sbjct: 220 EEDVVKEVMDITDGNGVDVFLE 241 >6BII-A nrPDB Length = 333 Score = 30.2 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 3/52 (5%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL 57 GK I + + IGQA A +G + S+ E EK G + + L Sbjct: 150 GKTIGIVGFGR-IGQAIAKR--AKGFGMRILYTARSRKPEAEKELGAEFKPL 198 >3FBG-A nrPDB Length = 346 Score = 30.2 bits (67), Expect = 0.85, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 23/48 (47%), Gaps = 2/48 (4%) Query: 5 DGKVIILTAAAQGIGQAAALAFARE-GAKVIATDINESKLQELEKYPG 51 +GK +++ A G+G + A A+ G +VI T ++ +K Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIEWTKKMGA 196 >5A3V-A nrPDB Length = 329 Score = 30.2 bits (67), Expect = 0.88, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 40/105 (38%), Gaps = 12/105 (11%) Query: 5 DGKVI--ILTAAAQGIGQAAALAFAR-EGAKVIAT--DINESKLQELEKYPGIQTRVLDV 59 GK ++TAA+ G+G A+ A+ A V AT N ++ L VLD Sbjct: 153 TGKKANILVTAASGGVG-HYAVQLAKLANAHVTATCGARNIEFVKSLGAD-----EVLDY 206 Query: 60 TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNL 104 + + ++ D + + A + + + +++ Sbjct: 207 KTPEGAALKSPSGKKYDAVVHCANGIPFSVF-EPNLSENGKVIDI 250 >4WOK-A nrPDB Length = 336 Score = 30.2 bits (67), Expect = 0.89, Method: Composition-based stats. Identities = 15/109 (13%), Positives = 36/109 (33%), Gaps = 7/109 (6%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 +++ A IG A A +G + D + Q ++ D+ + ++ + Sbjct: 13 NVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDF--VEGDILDQARLVE 70 Query: 68 FANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 + + + + A + G +D NV ++ A Sbjct: 71 TMEKYAPV-AVIHFAASAYVGE----SVEDPAKYYRNNVGGTQSLLDAC 114 >4OM8-A nrPDB Length = 309 Score = 30.2 bits (67), Expect = 0.89, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 19/41 (46%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD 58 +G A AR G +V+A D+ + ++ + VLD Sbjct: 13 MGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLD 53 >3ZWA-A nrPDB Length = 742 Score = 30.2 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 19/32 (59%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEKY 49 +G+ A++FAR G V+A + + +L +K Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKKI 358 >4DZR-A nrPDB Length = 215 Score = 30.2 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 44/134 (32%), Gaps = 12/134 (8%) Query: 5 DGKVIILTAAAQG-IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 G +I G I + ALA G V A D++ L + V+D Sbjct: 30 SGTRVIDVGTGSGCIAVSIALAC--PGVSVTAVDLSMDALAVARRNAERFGAVVDWAAAD 87 Query: 64 QIDQFANEVER---LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRS------MYLMIK 114 I+ ER + + ++ G + E D+ L + Y + Sbjct: 88 GIEWLIERAERGRPWHAIVSNPPYIPTGEIDQLEPSVRDYEPRLALDGGEDGLQFYRRMA 147 Query: 115 AFLPKMLAQKSGNI 128 A P +LA+ + Sbjct: 148 ALPPYVLARGRAGV 161 >1NHQ-A nrPDB Length = 447 Score = 29.8 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 6/47 (12%) Query: 3 RLDGKVI------ILTAAAQGIGQAAALAFAREGAKVIATDINESKL 43 +L K + ++ + IG AA AFA+ G KV DI + L Sbjct: 139 KLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPL 185 >5ZZM-A nrPDB Length = 426 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 10/61 (16%) Query: 10 ILTAAAQ--------GIGQA--AALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDV 59 ++T + + G G+A A A GA V+ D S QE + RV+D Sbjct: 44 VITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDR 103 Query: 60 T 60 T Sbjct: 104 T 104 >3PII-A nrPDB Length = 339 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 12/82 (14%) Query: 11 LTAAAQG-------IGQ--AAALAFARE-GAKVIATDINESKLQELEKYPGIQTRVLDVT 60 +T A G IG A+ +A+ G V+A DI + KL EL K G V++ Sbjct: 159 VTGAKPGEWVAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEKL-ELAKELG-ADLVVNPL 216 Query: 61 KKKQIDQFANEVERLDVLFNVA 82 K+ +V + A Sbjct: 217 KEDAAKFMKEKVGGVHAAVVTA 238 >1UUF-A nrPDB Length = 369 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Query: 17 GIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLD 76 GI A A GA V+A +E+K +E K G V + D+ A ++ D Sbjct: 210 GIKLAHA-----MGAHVVAFTTSEAK-REAAKALGADEVV----NSRNADEMAAHLKSFD 259 Query: 77 VLFN 80 + N Sbjct: 260 FILN 263 >3H0K-A nrPDB Length = 178 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 21/48 (43%), Gaps = 2/48 (4%) Query: 7 KVIILTAAAQGIGQ-AAALAFAREGAKVIATDINESKLQELEKYPGIQ 53 KVI++T G G+ A GAKVI K +E PG + Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGER 47 >1C0L-A nrPDB Length = 363 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Query: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN 39 M +V++L + IG ++AL AR+G V + Sbjct: 2 MMHSQKRVVVL--GSGVIGLSSALILARKGYSVHILARD 38 >3IP1-A nrPDB Length = 404 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 2/70 (2%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI 65 G +++ IG AA GA + + L K G V+D TK+ + Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELG-ADHVIDPTKENFV 271 Query: 66 DQFANEVERL 75 + + L Sbjct: 272 EAVLDYTNGL 281 >6APH-A nrPDB Length = 445 Score = 29.4 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 34/103 (33%), Gaps = 30/103 (29%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L GK +++ +G+ A +F G+ V T+I+ + Sbjct: 224 LAGKRVVVCGFGD-VGKGTAASFRGAGSIVTVTEIDPICALQAAMEGY------------ 270 Query: 64 QIDQFANEVERLDVLFNVA----------GFVHHGTVLDCEEK 96 EV++LD + + A G V ++K Sbjct: 271 -------EVKQLDTVVDNADIIITTTGNFGIVRGEHFEKMKDK 306 >1XDW-A nrPDB Length = 331 Score = 29.4 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 24/57 (42%), Gaps = 9/57 (15%) Query: 11 LTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 + + IG+ AA F GA VI D + + GI+ V+ + +++ Sbjct: 151 VVGLGR-IGRVAAQIFHGMGATVIGED--------VFEIKGIEDYCTQVSLDEVLEK 198 >5NUE-A nrPDB Length = 332 Score = 29.4 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 42/120 (35%), Gaps = 20/120 (16%) Query: 8 VIILTAAAQGIGQAAALAFAR---EGAK--VIATDINESKLQELEKYPGIQTRVLDVTKK 62 +++T AA IG A AR GA VI ++ E G++ ++D Sbjct: 7 RVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAE--ALNGVKMELIDAAFP 64 Query: 63 --KQIDQFANEVE---RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117 K + + VE ++V V GF + M+ NV +A Sbjct: 65 LLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMER------KDVMSKNVS--IYKSQAAA 116 >1ZDL-A nrPDB Length = 517 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 13/31 (41%), Gaps = 1/31 (3%) Query: 10 ILTAAAQGIGQAAALAFAREGAKVIATDINE 40 ++ G G A A A+ G KV D E Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADYVE 65 >4TSK-A nrPDB Length = 350 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 18/62 (29%), Gaps = 1/62 (1%) Query: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 L K I + G A A G V+ S + E V + ++ Sbjct: 15 LADKRIAVIGYGS-QGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADGFRVMAVGEAVEES 73 Query: 64 QI 65 + Sbjct: 74 DV 75 >1IE3-A nrPDB Length = 312 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 49/132 (37%), Gaps = 22/132 (16%) Query: 7 KVIILTAAAQGIGQAAALAFARE---GAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 KV +L AA GIGQA AL + G+++ DI PG+ + + Sbjct: 2 KVAVL-GAAGGIGQALALLLKTQLPSGSELSLYDIAPVT-------PGVAVDLSHIPTAV 53 Query: 64 QIDQFANE-----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 +I F+ E +E DV+ AG + D N+N + +++ Sbjct: 54 KIKGFSGEDATPALEGADVVLISAGVARKPGM------DRSDLFNVNAGIVKNLVQQVAK 107 Query: 119 KMLAQKSGNIIN 130 G I N Sbjct: 108 TCPKACIGIITN 119 >3TQH-A nrPDB Length = 321 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 31/75 (41%), Gaps = 6/75 (8%) Query: 5 DGKVIILTAAAQGIGQAAALAFARE-GAKVIATD--INESKLQELEKYPGIQTRVLD--V 59 G V+++ A A G+G A+ A++ G VI T N + L+ L I D + Sbjct: 152 QGDVVLIHAGAGGVG-HLAIQLAKQKGTTVITTASKRNHAFLKALGAEQCINYHEEDFLL 210 Query: 60 TKKKQIDQFANEVER 74 +D + V Sbjct: 211 AISTPVDAVIDLVGG 225 >4B4V-A nrPDB Length = 303 Score = 29.0 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGI 52 GK ++ + +G+ A+ + A V L EL K I Sbjct: 178 AGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQADI 225 >5KIA-A nrPDB Length = 351 Score = 29.0 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 8/70 (11%) Query: 4 LDGKVIILTAAAQGIGQ---AAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVT 60 L G+ +++T A IG A A V+ TDIN+ +L + TR ++V+ Sbjct: 170 LVGEDVLITGAGP-IGVMAVAIAKHVGAR--NVVITDINDYRLDLARRMG--ATRAVNVS 224 Query: 61 KKKQIDQFAN 70 ++ D A+ Sbjct: 225 RESLRDVMAD 234 >6H0D-A nrPDB Length = 403 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 23/51 (45%), Gaps = 4/51 (7%) Query: 8 VIILTAAAQG----IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQT 54 V ++ A+A G + QA A + G V A + S +E+++ G Sbjct: 258 VALIYASAYGNTSTLAQAIARGITKAGVAVTAINAETSNAEEIKEAIGKSA 308 >2YQ5-A nrPDB Length = 343 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 12/22 (54%), Positives = 14/22 (63%) Query: 18 IGQAAALAFAREGAKVIATDIN 39 IG A A F+ GAKVIA D+ Sbjct: 159 IGSAVAEIFSAMGAKVIAYDVA 180 >3R9I-A nrPDB Length = 260 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 6/56 (10%) Query: 7 KVIILTAAAQGIGQ-----AAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL 57 ++I++T+ G+G+ A A A++G K + D L+ L+ G + RV+ Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDF-AIGLRNLDLIMGCERRVV 57 >4MOP-A nrPDB Length = 633 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 8/68 (11%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD-VTKKKQID 66 V+I+ + IG A G KV DI E++ I + V +K ID Sbjct: 49 VVIV--GSGPIGCTYARELVGAGYKVAMFDIG-----EIDSGLKIGAHKKNTVEYQKNID 101 Query: 67 QFANEVER 74 +F N ++ Sbjct: 102 KFVNVIQG 109 >3D64-A nrPDB Length = 494 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 21/61 (34%), Gaps = 1/61 (1%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQ 64 GK+ ++ +G+ A + GA V T+I+ + + K Sbjct: 276 AGKIAVVAGYGD-VGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKAD 334 Query: 65 I 65 I Sbjct: 335 I 335 >1JAY-A nrPDB Length = 212 Score = 28.6 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 14/33 (42%), Gaps = 1/33 (3%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDIN 39 +V +L +G+ AL A G +++ Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRR 33 >1NLM-A nrPDB Length = 364 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 24/64 (37%), Gaps = 4/64 (6%) Query: 1 MGRLDGKVIILTAAAQG----IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRV 56 M GK +++ A G G A A +G +V + +L GI+ Sbjct: 1 MMSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDF 60 Query: 57 LDVT 60 + ++ Sbjct: 61 IRIS 64 >6CAU-A nrPDB Length = 472 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 29/85 (34%), Gaps = 13/85 (15%) Query: 17 GIGQA----AALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEV 72 GIG A A A +G K+ +DI SK + + GI+ I A + Sbjct: 19 GIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEENGIKVY---------IGHEAENI 69 Query: 73 ERLDVLFNVAGFVHHGTVLDCEEKD 97 + +VL + + Sbjct: 70 KNANVLVVSTAIDPENPEVKAAIEQ 94 >2BC1-A nrPDB Length = 490 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 2/39 (5%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ 44 +V ++ A IG A AF R+G +V+ D+ ++ L Sbjct: 195 KRVAVV--GAGYIGVELAEAFQRKGKEVVLIDVVDTCLA 231 >1LLU-A nrPDB Length = 342 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 5/64 (7%) Query: 14 AAQGIGQ--AAALAFARE-GAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFAN 70 A GIG A+ +AR G V A DI+++KL EL + G V + ++ ++ Sbjct: 175 AISGIGGLGHVAVQYARAMGLHVAAIDIDDAKL-ELARKLGASLTV-NARQEDPVEAIQR 232 Query: 71 EVER 74 ++ Sbjct: 233 DIGG 236 >3HDH-A nrPDB Length = 302 Score = 28.6 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 16/42 (38%), Gaps = 1/42 (2%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK 48 K + + +G A A G V+ D E L + +K Sbjct: 16 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKK 56 >5TC4-A nrPDB Length = 316 Score = 28.6 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 14/27 (51%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAK 32 GK +++ ++ +G A+ +GA Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH 185 >1F14-A nrPDB Length = 310 Score = 28.2 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 16/42 (38%), Gaps = 1/42 (2%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK 48 K + + +G A A G V+ D E L + +K Sbjct: 16 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKK 56 >1PGJ-A nrPDB Length = 478 Score = 28.2 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%), Gaps = 4/76 (5%) Query: 23 ALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLD---VLF 79 AL A +G KV + SK +E K ++ + ++ FA +++ +L Sbjct: 17 ALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILV 76 Query: 80 NVAGFVHHGTVLDCEE 95 AG T+ ++ Sbjct: 77 Q-AGAATDSTIEQLKK 91 >4R16-A nrPDB Length = 418 Score = 28.2 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEK 48 IG A+ FA G V+ DI ++++ Sbjct: 11 IGLPTAIMFASSGYDVVGYDIRSEVIKKINS 41 >1NPY-A nrPDB Length = 271 Score = 28.2 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 36/110 (32%), Gaps = 15/110 (13%) Query: 6 GKVI-ILTAAAQGIGQAAALAFAREGA-KVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 K ++ + G+ +A AF G K+ N Q L G Sbjct: 117 NKNAKVIVHGSGGMAKAVVAAFKNSGFEKLKIYARNVKTGQYLAALYGYAY--------- 167 Query: 64 QIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 I+ N+ + D+L NV G + + + + N + ++ Sbjct: 168 -INSLENQ--QADILVNVTSIGMKGGKEEMDLA-FPKAFIDNASVAFDVV 213 >6C6P-A nrPDB Length = 458 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 28/76 (36%), Gaps = 11/76 (14%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY---PGIQTRVLDVTKKKQI 65 +I+ A +G A A +R+G KV + + + + PG + D+ Sbjct: 10 VIIVGAGV-LGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLG----- 63 Query: 66 DQFANEVERLDVLFNV 81 + VE LD Sbjct: 64 --LGDTVEGLDAQVVN 77 >1DB3-A nrPDB Length = 372 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 31/84 (36%), Gaps = 11/84 (13%) Query: 7 KVIILTAAAQGIGQAAALAFAREGAKVI-----ATDINESKLQELEKY-----PGIQTRV 56 KV ++T G A +G +V A+ N ++ + + P Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 57 LDVTKKKQIDQFANEVERLDVLFN 80 D++ + + EV+ D ++N Sbjct: 62 GDLSDTSNLTRILREVQP-DEVYN 84 >3DQQ-A nrPDB Length = 421 Score = 27.8 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 131 MSSVASSVKGVVNRCVYSTTKA--AVIGLTKSVAADFIQQGIRCNCVCPG 178 +S+ AS+ + Y T+A AV L +AA + GI V G Sbjct: 313 ISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGG 362 >1X74-A nrPDB Length = 360 Score = 27.8 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 23/67 (34%), Gaps = 4/67 (5%) Query: 17 GIGQA--AALAFAREGAKVIATDINE--SKLQELEKYPGIQTRVLDVTKKKQIDQFANEV 72 GIG AA+ GA V+ D + + D+ + ++ + Sbjct: 15 GIGPGPHAAMILGDLGADVVRIDRPSSVDGISRDAMLRNRRIVTADLKSDQGLELALKLI 74 Query: 73 ERLDVLF 79 + DVL Sbjct: 75 AKADVLI 81 >4H05-A nrPDB Length = 273 Score = 27.8 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 38/104 (36%), Gaps = 14/104 (13%) Query: 16 QGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEV--- 72 +G G+ + A GA V E + L + RV++ +++ E Sbjct: 39 RGGGRELFVKVAALGAGVGLLGEAERLVW-LAEVGIPVPRVVEGGGDERVAWLVTEAVPG 97 Query: 73 ----------ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNV 106 +RLDV +AG LD E +D S+ + V Sbjct: 98 RPASARWPREQRLDVAVALAGLARSLHALDWERCPFDRSLAVTV 141 >3K96-A nrPDB Length = 356 Score = 27.8 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 59/168 (35%), Gaps = 12/168 (7%) Query: 14 AAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ---FAN 70 A G A AL AR+G KV + E++ + + + + Sbjct: 36 GAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNNRYLPNYPFPETLKAYCDLKA 95 Query: 71 EVERL-DVLFNVAGFVHHGTVLDCEE-KDWDFSMNLNVRSMYLMIKAFLPKMLAQKSG-- 126 +E + D+L V F H + + D + + + + L +++A + G Sbjct: 96 SLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAWGTKGLAKGSR-LLHEVVATELGQV 154 Query: 127 --NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 +I+ S+A+ V + V + + +K + Q R Sbjct: 155 PMAVISGPSLATEVAANLPTAVSLASNNS--QFSKDLIERLHGQRFRV 200 >4UUP-A nrPDB Length = 341 Score = 27.8 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 12/20 (60%) Query: 9 IILTAAAQGIGQAAALAFAR 28 +++T AA IG A A A+ Sbjct: 7 VLITGAAGQIGYALAFRIAK 26 >4DVJ-A nrPDB Length = 363 Score = 27.5 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 29/66 (43%), Gaps = 3/66 (4%) Query: 9 IILTAAAQGIGQAAALAFAREGAKV-IATDINESKLQELEKYPGIQTRVLDVTKKKQIDQ 67 I++ A G+G + A+ AR+ + + + + QE K G V+D +K + Sbjct: 175 ILIVGGAGGVG-SIAVQIARQRTDLTVIATASRPETQEWVKSLGAH-HVIDHSKPLAAEV 232 Query: 68 FANEVE 73 A + Sbjct: 233 AALGLG 238 >6DKH-A nrPDB Length = 346 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 25/76 (32%), Gaps = 3/76 (3%) Query: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK 61 G L GK + ++ IG A GA I + L K G V + Sbjct: 169 GELQGKRVFISGVGP-IGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNP--Q 225 Query: 62 KKQIDQFANEVERLDV 77 +D + E DV Sbjct: 226 NDDMDHWKAEKGYFDV 241 >1YXY-A nrPDB Length = 234 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 25/62 (40%), Gaps = 7/62 (11%) Query: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 K K++ Q G II S + + +YS T ++ L A + GIR N Sbjct: 4 KPTKEKLMEQLKGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRAN 56 Query: 174 CV 175 V Sbjct: 57 SV 58 >1QYC-A nrPDB Length = 308 Score = 27.5 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 26/82 (31%), Gaps = 7/82 (8%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIA------TDINESKLQELEKYPGIQTRVLDVTK 61 I+L A IG+ A A G N K Q LE + ++ Sbjct: 6 RILLIGATGYIGRHVAKASLDLGHPTFLLVRESTASSNSEKAQLLESFKASGANIV-HGS 64 Query: 62 KKQIDQFANEVERLDVLFNVAG 83 V+ +DV+ + G Sbjct: 65 IDDHASLVEAVKNVDVVISTVG 86 >3F6T-A nrPDB Length = 533 Score = 27.5 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 17/29 (58%) Query: 173 NCVCPGTVDTPSLQERIQARGNPEEARND 201 N + G ++T ++ER+ A +P++ D Sbjct: 71 NGIMAGYINTDGIRERLFAFLDPDKNDED 99 >2QVR-A nrPDB Length = 332 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 43/101 (42%), Gaps = 15/101 (14%) Query: 28 REGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQI---DQFANEVERLDVLFNVA-- 82 + GAK+I DIN++ L ++ G + +V +K + ++ ++ D++ +A Sbjct: 30 KLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASE 89 Query: 83 ---------GFVHHGTVLDCEEKDWDFSMNLNVR-SMYLMI 113 G H V+ + D ++++NV I Sbjct: 90 EEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSI 130 >4EEZ-A nrPDB Length = 348 Score = 27.5 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 14 AAQGIGQAAALAFARE--GAKVIATDINESKLQELEKYPG-IQTRVLDVTKKKQIDQFAN 70 A G+G A+ +A+ GAKVIA DIN+ KL +K + DV +I + Sbjct: 171 GAGGLGN-LAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVNPVDEIKKITG 229 Query: 71 EVE 73 + Sbjct: 230 GLG 232 >2ZJ1-A nrPDB Length = 495 Score = 27.1 bits (59), Expect = 6.7, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 30/79 (37%), Gaps = 15/79 (18%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINE-SKLQELEKYPGIQTRVLDVTKKKQ 64 GK +++ +G+ A A +GA+V T+I+ + LQ + + Sbjct: 275 GKKVLICGYGD-VGKGCAEAMKGQGARVSVTEIDPINALQAMMEGF-------------D 320 Query: 65 IDQFANEVERLDVLFNVAG 83 + + D++ G Sbjct: 321 VVTVEEAIGDADIVVTATG 339 >3K30-A nrPDB Length = 690 Score = 27.1 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 7/45 (15%), Positives = 15/45 (33%), Gaps = 1/45 (2%) Query: 8 VIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGI 52 +++ A G AA A G V+ + + + + Sbjct: 393 RVLVVGAGPS-GLEAARALGVRGYDVVLAEAGRDLGGRVTQESAL 436 >1EZ1-A nrPDB Length = 392 Score = 27.1 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 34/88 (38%), Gaps = 4/88 (4%) Query: 14 AAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVE 73 + +G+ A+ R G +VIA D + ++ V+++ + + E+E Sbjct: 19 GSGELGKEVAIECQRLGVEVIAVDR---YADAPAMHVAHRSHVINMLDGDALRRVV-ELE 74 Query: 74 RLDVLFNVAGFVHHGTVLDCEEKDWDFS 101 + + + ++ EE+ + Sbjct: 75 KPHYIVPEIEAIATDMLIQLEEEGLNVV 102 >3ORR-A nrPDB Length = 377 Score = 27.1 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 27/61 (44%), Gaps = 6/61 (9%) Query: 18 IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDV 77 +G+ A + + G KV+ D +E + IQ + D +K ++Q + DV Sbjct: 23 LGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDD---EKALNQLGQ---KCDV 76 Query: 78 L 78 + Sbjct: 77 I 77 >5E9F-A nrPDB Length = 560 Score = 27.1 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 11/84 (13%), Positives = 27/84 (32%), Gaps = 7/84 (8%) Query: 1 MGRLDGKVIILTAAAQGI--GQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLD 58 + R D V+ + ++ I + A + + A + + + + G+ D Sbjct: 314 LKRFDDAVVDVINSSSSIRNPKDVAAKYLQ-----AAKGKSNREARAIASSLGVPEIFFD 368 Query: 59 VTKKKQIDQFANEVERLDVLFNVA 82 + + + D N A Sbjct: 369 WDSPRTREGYFRIKGGCDCAINRA 392 >4B3J-A nrPDB Length = 736 Score = 27.1 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 9/85 (10%) Query: 14 AAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVE 73 A +G A A+ G +V+ D++ L+ K G ++ + K +++ E Sbjct: 348 GAGMMGAGIAYVSAKAGYEVVLKDVS---LEAAAKGKGYSEKL----EAKALERGRTTQE 400 Query: 74 RLDVLFNVAGFVHHGTVLDCEEKDW 98 R D L A D + D+ Sbjct: 401 RSDALL--ARITPTADAADFKGVDF 423 >2XHZ-A nrPDB Length = 183 Score = 27.1 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 15/31 (48%), Gaps = 1/31 (3%) Query: 1 MGRLDGKVII-LTAAAQGIGQAAALAFAREG 30 M GKV++ A+ IG+ A FA G Sbjct: 45 MFWCKGKVVVMGMGASGHIGRKMAATFASTG 75 >2MSW-A nrPDB Length = 125 Score = 27.1 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 25 AFAREGAKVIATDINESKLQELEKYPGIQTRVLDV 59 AF EGA+V+ E L+ L P I VLDV Sbjct: 24 AFEDEGAEVVVAATCEQALKSLADNP-IDVAVLDV 57 >4A5O-A nrPDB Length = 286 Score = 26.7 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 12/30 (40%) Query: 9 IILTAAAQGIGQAAALAFAREGAKVIATDI 38 ++ A+ +G+ AL G V T Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHR 193 >5ZKP-A nrPDB Length = 466 Score = 26.7 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 21/59 (35%), Gaps = 6/59 (10%) Query: 3 RLDGKVIILTAAAQG----IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL 57 + K +I+ + G + A A G +V + + ++ + G +L Sbjct: 216 LMQAKALIVYGSTTGNTEYTAETIARELADAGYEV--DSRDAASVEAGGLFEGFDLVLL 272 >5U9C-A nrPDB Length = 292 Score = 26.7 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 28/87 (32%), Gaps = 12/87 (13%) Query: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK-YPGIQTRVLDV----T 60 + I++T +G A VI T+ N L E + I DV Sbjct: 5 KRKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHFA 64 Query: 61 KKKQIDQFANEVERLDVLFNVAGFVHH 87 + +D E R AG +H Sbjct: 65 AETDVDLCEREPAR-------AGIYNH 84 >3AOE-A nrPDB Length = 424 Score = 26.7 bits (58), Expect = 9.5, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 20/57 (35%), Gaps = 4/57 (7%) Query: 5 DGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTK 61 G+ + +TAAA A + EGA+V + RV+ V Sbjct: 198 TGRGVFITAAA----AAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQD 250 >5G6R-A nrPDB Length = 295 Score = 26.7 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 43/119 (36%), Gaps = 9/119 (7%) Query: 127 NIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR-CNCVCPGTVDTPSL 185 I + ++ +++ Y K +V T + A ++QG + + + G + Sbjct: 6 GIFGLGAMGTALAAKYLEHGY---KTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLI 62 Query: 186 QERIQARGNPEEARNDFLKRQKTGRF-----ATAEEIAMLCVYLASDESAYVTGNPVII 239 + E+A D L+ + T + L ++ S + Y+ G + + Sbjct: 63 IICLLNNQVVEDALRDALQTLPSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIMAV 121 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.160 0.466 Lambda K H 0.267 0.0489 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,945,181 Number of Sequences: 36641 Number of extensions: 467341 Number of successful extensions: 3496 Number of sequences better than 10.0: 474 Number of HSP's better than 10.0 without gapping: 433 Number of HSP's successfully gapped in prelim test: 220 Number of HSP's that attempted gapping in prelim test: 2055 Number of HSP's gapped (non-prelim): 706 length of query: 245 length of database: 10,336,785 effective HSP length: 94 effective length of query: 151 effective length of database: 6,892,531 effective search space: 1040772181 effective search space used: 1040772181 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.7 bits)