BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BR01 (284 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ZD1-A nrPDB 596 e-171 1CJM-A nrPDB 183 9e-47 2GWH-A nrPDB 176 8e-45 3BFX-A nrPDB 174 4e-44 3U3O-A nrPDB 174 5e-44 2Z5F-A nrPDB 172 2e-43 1AQU-A nrPDB 165 3e-41 2REO-A nrPDB 164 4e-41 4JVN-A nrPDB 163 9e-41 2ZVQ-X nrPDB 159 1e-39 1Q22-A nrPDB 146 8e-36 1Q1Q-A nrPDB 146 1e-35 1OV4-A nrPDB 138 2e-33 5X2B-D nrPDB 131 3e-31 1X8L-A nrPDB 121 3e-28 1Q44-A nrPDB 96 2e-20 5MEK-A nrPDB 93 1e-19 3MGC-A nrPDB 56 1e-08 3NIB-A nrPDB 52 3e-07 4EEC-A nrPDB 36 0.017 3RNL-A nrPDB 35 0.047 5KPS-A nrPDB 31 0.67 5Y61-B nrPDB 31 0.75 4ZHW-A nrPDB 30 0.84 5L3P-z nrPDB 30 0.88 4LJI-A nrPDB 29 1.8 1NST-A nrPDB 29 2.3 4GBM-A nrPDB 29 2.3 3WD0-A nrPDB 28 3.0 4WVX-A nrPDB 28 4.4 4ZGR-A nrPDB 28 4.6 5TXK-A nrPDB 27 7.2 6IC4-G nrPDB 27 8.2 >1ZD1-A nrPDB Length = 284 Score = 596 bits (1536), Expect = e-171, Method: Compositional matrix adjust. Identities = 284/284 (100%), Positives = 284/284 (100%) Query: 1 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL 60 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL Sbjct: 1 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL 60 Query: 61 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD 120 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD Sbjct: 61 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD 120 Query: 121 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ 180 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ Sbjct: 121 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ 180 Query: 181 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA 240 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA Sbjct: 181 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA 240 Query: 241 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL Sbjct: 241 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 >1CJM-A nrPDB Length = 295 Score = 183 bits (464), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 99/275 (36%), Positives = 150/275 (54%), Gaps = 18/275 (6%) Query: 24 GVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNID 83 GV L + + + +F RP D+ I TYPKSGT+ + +++ ++ QG D ++ I Sbjct: 17 GVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIY 76 Query: 84 EQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLV 139 ++P LE PG L+ +K+ PRLIKSHLP LP L + KV+Y+ARNPKD+ Sbjct: 77 VRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVA 136 Query: 140 VSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDM 199 VSYY FHR + GT+ F +FM ++ YGSW++HVQE+WE VL+L YEDM Sbjct: 137 VSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDM 196 Query: 200 HRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALP-----------V 245 + ++++ F+G S + ++ + +H + N +P + Sbjct: 197 KENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFM 256 Query: 246 GRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 +G G WK FTV+ NE+FD Y +KM C L+F Sbjct: 257 RKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSF 291 >2GWH-A nrPDB Length = 298 Score = 176 bits (447), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 96/265 (36%), Positives = 148/265 (55%), Gaps = 18/265 (6%) Query: 36 EEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQP- 94 ++I NF +P D+ I TYPK+GT+ QE+V L+ D ++ ++ P LE P Sbjct: 32 DKIWNFQAKPDDLLISTYPKAGTTWTQEIVELIQNEGDVEKSKRAPTHQRFPFLEMKIPS 91 Query: 95 ---GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRT 151 GL+ + SPR++K+HLP+ LP L + K+IY+ARNPKD +VSYY F R + Sbjct: 92 LGSGLEQAHAMPSPRILKTHLPFHLLPPSLLEKNCKIIYVARNPKDNMVSYYHFQRMNKA 151 Query: 152 MSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLA 211 + GT++E+ F+ K+ +GSW EHV+ +WE + +L+L YEDM ++ +++LA Sbjct: 152 LPAPGTWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKHRILYLFYEDMKKNPKHEIQKLA 211 Query: 212 RFLGVSCDKAQLEALTEHCHQLV---DQCCNAEALP-----------VGRGRVGLWKDIF 257 F+G D L+ + + V + N ++P + +G VG WK F Sbjct: 212 EFIGKKLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAEIMDHSISPFMRKGAVGDWKKHF 271 Query: 258 TVSMNEKFDLVYKQKMGKCDLTFDF 282 TV+ NE+FD YK+KM LTF F Sbjct: 272 TVAQNERFDEDYKKKMTDTRLTFHF 296 >3BFX-A nrPDB Length = 296 Score = 174 bits (441), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 95/288 (32%), Positives = 156/288 (54%), Gaps = 24/288 (8%) Query: 18 KYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEI 77 K E G L P +I +F +P D+ I TYPK+GT+ +QE+V ++ Q D ++ Sbjct: 12 KLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKC 71 Query: 78 GLMNIDEQLPVLEY---PQP-GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMAR 133 I + P +E+ PQP G++ K + SPR++K+HL + LP + K +Y+AR Sbjct: 72 QRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVAR 131 Query: 134 NPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLF 193 N KD +VSYY F R + GT++E+ F+N K+ +GSWF+HV+ +WE + +LF Sbjct: 132 NAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILF 191 Query: 194 LKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC-----------------HQLVDQ 236 L YED+ RD + ++ +F+G D+ L+ + + ++DQ Sbjct: 192 LFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQ 251 Query: 237 CCNAEALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 ++ + +G VG WK+ FTV+ NE+FD +Y++KM + F L Sbjct: 252 SISSF---MRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFSMEL 296 >3U3O-A nrPDB Length = 315 Score = 174 bits (440), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 93/275 (33%), Positives = 150/275 (54%), Gaps = 18/275 (6%) Query: 24 GVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNID 83 GV L + + + +F RP D+ I TYPKSGT+ + +++ ++ QG D ++ I Sbjct: 37 GVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF 96 Query: 84 EQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLV 139 ++P LE+ PG ++ +K+ +PRL+K+HLP LP L + KV+Y+ARN KD+ Sbjct: 97 MRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVA 156 Query: 140 VSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDM 199 VSYY F+ + GT+ F +FM ++ YGSW++HVQE+WE VL+L YEDM Sbjct: 157 VSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDM 216 Query: 200 HRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALP-----------V 245 + ++++ F+G S + ++ + +H + N +P + Sbjct: 217 KENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFM 276 Query: 246 GRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 +G G WK FTV+ NE+FD Y +KM C L+F Sbjct: 277 RKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSF 311 >2Z5F-A nrPDB Length = 298 Score = 172 bits (436), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 94/277 (33%), Positives = 148/277 (53%), Gaps = 19/277 (6%) Query: 23 HGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNI 82 HG + E+I F RP D+ I TYPKSGT+ + E++ ++ D ++ I Sbjct: 18 HGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDMILNDGDIEKCKRGFI 77 Query: 83 DEQLPVLEYPQPGL-----DIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKD 137 E++P+LE PGL + +++ SPR++K+HLP LP + K+IY+ARN KD Sbjct: 78 TEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNCKMIYLARNAKD 137 Query: 138 LVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYE 197 + VSYY F + GT++E+ +F+ K+ YGSWF HV+ +W+ + + +LFL YE Sbjct: 138 VSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKRKEEHPILFLYYE 197 Query: 198 DMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLV---DQCCNAEALPVG-------- 246 DM + ++++ RFL + + L+ + H V + N LP Sbjct: 198 DMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTTVMDHSKSP 257 Query: 247 ---RGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 +G G WK+ FTV+ NEKFD +Y+ +M K L F Sbjct: 258 FMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQF 294 >1AQU-A nrPDB Length = 297 Score = 165 bits (417), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 95/285 (33%), Positives = 150/285 (52%), Gaps = 18/285 (6%) Query: 14 EFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD 73 E+ + EF GV + E++ F RP D+ I TYPKSGT+ + EVVY++ + D Sbjct: 9 EYYEVFGEFRGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGD 68 Query: 74 PDEIGLMNIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVI 129 ++ I ++P LE G+ +KE SPR++K+HLP + LP+ + K+I Sbjct: 69 VEKCKEDAIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMI 128 Query: 130 YMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDS 189 Y+ RN KD+ VSYY F + + +F EF +FM ++ YGSW++HV+ +WE +S Sbjct: 129 YLCRNAKDVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNS 188 Query: 190 NVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH-------------QLVDQ 236 VLF+ YEDM D+ V +L FL ++ + +H + ++ Sbjct: 189 RVLFMFYEDMKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEE 248 Query: 237 CCNAEALPVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 N + P R G +G WK+ F ++ E+FD YKQ+M C + F Sbjct: 249 MMNQKVSPFMRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKF 293 >2REO-A nrPDB Length = 305 Score = 164 bits (415), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 98/300 (32%), Positives = 157/300 (52%), Gaps = 20/300 (6%) Query: 1 MAESEAETPSTPGEFES-KYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTS 59 MA+ E P+ + E E GV + E++ANF +P D+ + TYPKSGT+ Sbjct: 2 MAKIEKNAPTMEKKPELFNIMEVDGVPTLILSKEWWEKVANFQAKPDDLILATYPKSGTT 61 Query: 60 LLQEVVYLVSQGADPDEIGLMNIDEQLPVLE--YP---QPGLDIIKELTSPRLIKSHLPY 114 + E++ ++ D ++ ++ LE +P +P L+ + E++SP+LIK+HLP Sbjct: 62 WMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPS 121 Query: 115 RFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGS 174 +P + + K++Y+ARNPKD +VSYY FHR M +EF +FM+ K+ GS Sbjct: 122 HLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGS 181 Query: 175 WFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLV 234 WF+HV+ +W + +L+L YED+ +D +E++ +FL + L + H V Sbjct: 182 WFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDV 241 Query: 235 ---DQCCNAEALPVG-----------RGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 + N LP +G G WK+ FTV+ NE+FD Y++KM LTF Sbjct: 242 MKQNPMTNYTTLPTSIMDHSISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTF 301 >4JVN-A nrPDB Length = 294 Score = 163 bits (412), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 95/285 (33%), Positives = 149/285 (52%), Gaps = 18/285 (6%) Query: 14 EFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD 73 ++ K+ E HG+ + + + F RP D+ I TYPKSGT+ + E+VY++ + D Sbjct: 6 DYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGD 65 Query: 74 PDEIGLMNIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVI 129 ++ I ++P LE + G+ + E+ SPR++K+HLP LP+ D K+I Sbjct: 66 VEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKII 125 Query: 130 YMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDS 189 Y+ RN KD+ VS+Y F + G+F EF +FM ++ YGSW++HV+ +WE Sbjct: 126 YLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSP 185 Query: 190 NVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH-------------QLVDQ 236 VLFL YED+ D+ V +L FL + ++ + H L D+ Sbjct: 186 RVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDE 245 Query: 237 CCNAEALPVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 N + P R G G WK+ FT ++NEKFD Y+Q+M + L F Sbjct: 246 IMNQKLSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKF 290 >2ZVQ-X nrPDB Length = 295 Score = 159 bits (402), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 85/262 (32%), Positives = 144/262 (54%), Gaps = 18/262 (6%) Query: 37 EIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGL 96 ++ +F RP D+ I TYPKSGT+ + E++ L+ D ++ I +++P +E PG+ Sbjct: 30 QVESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGI 89 Query: 97 ----DIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTM 152 +++ + SPR++K+HLP + LPS D K+IY+ARN KD+VVSYY F++ + Sbjct: 90 TNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIH 149 Query: 153 SYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLAR 212 GT++EF +FM ++ +G W++HV+ +WE R + +L+L YEDM + ++++ + Sbjct: 150 PEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEIQKILK 209 Query: 213 FLGVSCDKAQLEALTEHCH-------------QLVDQCCNAEALPVGR-GRVGLWKDIFT 258 FL + L + H ++ + + P R G G WK+ FT Sbjct: 210 FLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSPFMRKGISGDWKNQFT 269 Query: 259 VSMNEKFDLVYKQKMGKCDLTF 280 V+ EKF+ Y +KM L F Sbjct: 270 VAQYEKFEEDYVKKMEDSTLKF 291 >1Q22-A nrPDB Length = 299 Score = 146 bits (369), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 94/282 (33%), Positives = 146/282 (51%), Gaps = 28/282 (9%) Query: 12 PGEFESKYFEFHGVRLPPFCRG--KMEEIA----NFPVRPSDVWIVTYPKSGTSLLQEVV 65 PGE YF + GV PF G +E I+ VR D++I+TYPKSGT+ + E++ Sbjct: 15 PGE----YFRYKGV---PFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEII 67 Query: 66 YLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGD 125 L+ + DP I + I E+ P E G + + SPRL+ SHLP + + Sbjct: 68 CLILKEGDPSWIRSVPIWERAPWCETIV-GAFSLPDQYSPRLMSSHLPIQIFTKAFFSSK 126 Query: 126 SKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEH 185 +KVIYM RNP+D+VVS Y + + + GT +F R F+ ++ +GSWF+H++ + Sbjct: 127 AKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRM 186 Query: 186 RMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEH---CHQLVDQCCNAEA 242 + N LF+ YE++ +DL VE++ FLG K L ++ H + N Sbjct: 187 KGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTL 246 Query: 243 LP-----------VGRGRVGLWKDIFTVSMNEKFDLVYKQKM 273 LP + +G G WK+ FTV+ +E FD Y+++M Sbjct: 247 LPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQM 288 >1Q1Q-A nrPDB Length = 350 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 94/282 (33%), Positives = 146/282 (51%), Gaps = 28/282 (9%) Query: 12 PGEFESKYFEFHGVRLPPFCRG--KMEEIA----NFPVRPSDVWIVTYPKSGTSLLQEVV 65 PGE YF + GV PF G +E I+ VR D++I+TYPKSGT+ + E++ Sbjct: 13 PGE----YFRYKGV---PFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEII 65 Query: 66 YLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGD 125 L+ + DP I + I E+ P E G + + SPRL+ SHLP + + Sbjct: 66 CLILKEGDPSWIRSVPIWERAPWCETIV-GAFSLPDQYSPRLMSSHLPIQIFTKAFFSSK 124 Query: 126 SKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEH 185 +KVIYM RNP+D+VVS Y + + + GT +F R F+ ++ +GSWF+H++ + Sbjct: 125 AKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRM 184 Query: 186 RMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEH---CHQLVDQCCNAEA 242 + N LF+ YE++ +DL VE++ FLG K L ++ H + N Sbjct: 185 KGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTL 244 Query: 243 LP-----------VGRGRVGLWKDIFTVSMNEKFDLVYKQKM 273 LP + +G G WK+ FTV+ +E FD Y+++M Sbjct: 245 LPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQM 286 >1OV4-A nrPDB Length = 293 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 83/272 (30%), Positives = 143/272 (52%), Gaps = 17/272 (6%) Query: 19 YFEFHGVRLPP--FCRGKMEEIAN-FPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPD 75 + F G+ P F + ++ + F +R DV I+TYPKSGT+ L E++ L+ D Sbjct: 13 FLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAK 72 Query: 76 EIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNP 135 I + I E+ P +E + G + E SPRL SHLP + P + +KVIY+ RNP Sbjct: 73 WIQSVPIWERSPWVE-SEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNP 131 Query: 136 KDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLK 195 +D++VS Y F ++++ + +++E+ F + YGSWF+H+ + R + N L L Sbjct: 132 RDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLS 191 Query: 196 YEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALPVG------ 246 YE++ +D +E++ +FLG + + +L + ++ ++ N L V Sbjct: 192 YEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKT 251 Query: 247 ----RGRVGLWKDIFTVSMNEKFDLVYKQKMG 274 +G G WK+ FTV+ E FD ++++KM Sbjct: 252 QLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 283 >5X2B-D nrPDB Length = 281 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 127/259 (49%), Gaps = 33/259 (12%) Query: 40 NFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGA----DPDEIGLMNIDEQLPVLEYPQPG 95 +F R D+++V+YPKSGT L EV+ + P E+G ++ E+L Sbjct: 25 SFDAREDDIFLVSYPKSGTHWLAEVIERIPDAGITLTSPIELGDISKFEEL--------- 75 Query: 96 LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYR 155 K + R I +HL Y LP + K+IY+ RNPKD VS + ++R + Sbjct: 76 ----KRIPKRRAIPTHLNYEMLPVTVKQKQCKIIYIVRNPKDTAVSMFHYYRDNPNLPST 131 Query: 156 GTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLG 215 T+ F F+ + YGSWF+HV + EH+ D NVLF+ YE+M +D V ++++ FLG Sbjct: 132 ETWAAFLELFLKGDVVYGSWFDHVLSWEEHKNDKNVLFIFYEEMKKDFVKSLKKITAFLG 191 Query: 216 VSCDKAQL--------------EALTEHC--HQLVDQCCNAEALPVGRGRVGLWKDIFTV 259 + + +++ A E+C + ++ + L +G VG W + FT Sbjct: 192 IDVNDSEMAKIARSTSFSEMKSNAAKENCDPNHVICALTSDRNLVFRKGVVGDWINYFTP 251 Query: 260 SMNEKFDLVYKQKMGKCDL 278 N FD ++ +KM D+ Sbjct: 252 KQNRGFDELFTEKMRNSDV 270 >1X8L-A nrPDB Length = 351 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 79/293 (26%), Positives = 141/293 (48%), Gaps = 52/293 (17%) Query: 38 IANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGA----------------------DPD 75 I N P+RP+DV++ +Y +SGT++ QE+V+L+ DP+ Sbjct: 56 IYNMPLRPTDVFVASYQRSGTTMTQELVWLIENDLNFEAAKTYMSLRYIYLDGFMIYDPE 115 Query: 76 EIGLMN----------IDEQLPVLEYP-QPGLDIIKEL--TSPRLIKSHLPYRFLPSDLH 122 + N ++ L +LEY +PG ++ + T R +K+HLP +P ++ Sbjct: 116 KQEEYNDILPNPENLDMERYLGLLEYSSRPGSSLLAAVPPTEKRFVKTHLPLSLMPPNML 175 Query: 123 NGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEF 182 + K++Y+AR+P+D+ VS + R L ++ + F++F F +FEHV+E Sbjct: 176 DT-VKMVYLARDPRDVAVSSFHHARLLYLLNKQSNFKDFWEMFHRGLYTLTPYFEHVKEA 234 Query: 183 WEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------------ 230 W R D N+LFL YED +DL + ++A FLG + Q++ L+EH Sbjct: 235 WAKRHDPNMLFLFYEDYLKDLPGSIARIADFLGKKLSEEQIQRLSEHLNFEKFKNNGAVN 294 Query: 231 ---HQLVDQCCNAEALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 ++ + + E + +G+ G W+D F M ++ + K + DL + Sbjct: 295 MEDYREIGILADGEHF-IRKGKAGCWRDYFDEEMTKQAEKWIKDNLKDTDLRY 346 >1Q44-A nrPDB Length = 326 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 35/303 (11%) Query: 9 PSTPGEFESKYFEFHGV-RLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYL 67 P G S+ +EF G+ +G + F + SD+ +VT PKSGT+ L+ +V+ Sbjct: 28 PKEKGWLVSEIYEFQGLWHTQAILQGILICQKRFEAKDSDIILVTNPKSGTTWLKALVFA 87 Query: 68 V---------SQGADPDEIGLMNIDEQLPVLE---YPQPGLDIIKELTSPRLIKSHLPYR 115 + S G P + + N +P LE Y P D L SPRL+ +H+ + Sbjct: 88 LLNRHKFPVSSSGNHP--LLVTNPHLLVPFLEGVYYESPDFDF-SSLPSPRLMNTHISHL 144 Query: 116 FLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSL---RTMSYRGTFQEFCRRFMNDKLGY 172 LP + + K++Y RNPKD+ VS + F + L T Y ++ F K Sbjct: 145 SLPESVKSSSCKIVYCCRNPKDMFVSLWHFGKKLAPEETADY--PIEKAVEAFCEGKFIG 202 Query: 173 GSWFEHVQEFW-EHRMDSN-VLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC 230 G +++H+ E+W R + N VLF+ YE++ + ++++A FL + + Sbjct: 203 GPFWDHILEYWYASRENPNKVLFVTYEELKKQTEVEMKRIAEFLECGFIEEEEVREIVKL 262 Query: 231 ---HQLVDQCCNAEA-LPVG--------RGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDL 278 L + N E LP G +G +G W+D + S+ E+ D ++K L Sbjct: 263 CSFESLSNLEVNKEGKLPNGIETKTFFRKGEIGGWRDTLSESLAEEIDRTIEEKFKGSGL 322 Query: 279 TFD 281 F Sbjct: 323 KFS 325 >5MEK-A nrPDB Length = 322 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 74/286 (25%), Positives = 127/286 (44%), Gaps = 39/286 (13%) Query: 27 LPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDE----IGLMNI 82 LP G + F RPSD + +YPK+GT+ L+ + + ++ + D+ + N Sbjct: 40 LPSLLEGCIHAQEFFQARPSDFLVCSYPKTGTTWLKALTFAIANRSRFDDSSNPLLKRNP 99 Query: 83 DEQLPVLE--YPQ-PGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLV 139 E +P +E +P P +D++K+ + L +H+PY LP + K++Y+ R PKD Sbjct: 100 HEFVPYIEIDFPFFPEVDVLKDKGN-TLFSTHIPYELLPDSVVKSGCKMVYIWREPKDTF 158 Query: 140 VSYYQFHRSLRT-----MSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDS--NVL 192 +S + F RT + +F FCR GYG + H+ +W+ ++ +L Sbjct: 159 ISMWTFLHKERTELGPVSNLEESFDMFCRGLS----GYGPYLNHILAYWKAYQENPDRIL 214 Query: 193 FLKYEDMHRDLVTMVEQLARFLGVS-----------------CDKAQLEALTEHCHQLVD 235 FLKYE M D + V+ LA F+G C L+ L + + Sbjct: 215 FLKYETMRADPLPYVKSLAEFMGHGFTAEEEEKGVVEKVVNLCSFETLKNLEANKGEKDR 274 Query: 236 Q---CCNAEALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDL 278 + A + +G+VG W + T M + D + ++K L Sbjct: 275 EDRPGVYANSAYFRKGKVGDWSNYLTPEMAARIDGLMEEKFKGTGL 320 >3MGC-A nrPDB Length = 319 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/184 (27%), Positives = 88/184 (47%), Gaps = 22/184 (11%) Query: 49 WIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDII-KELTSPRL 107 WI +YPK+G + ++ ++ G P +ID + LE D+ E P L Sbjct: 40 WIASYPKAGNTWVRCMLAAYITGKAPQV--WNDIDAESLTLEAMLRFGDLPPAEPMEPVL 97 Query: 108 IKSHLPYRFLPSDLHN-GDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFM 166 +K+HL L+ +KV+Y+ RNP+D+++S + R + ++F R+F+ Sbjct: 98 VKTHLKADVPVLGLYGEATAKVLYLVRNPRDMLLSSMRMASISRDDVEKS--RDFARKFI 155 Query: 167 -NDKLGYG-----------SWFEHVQEFWEHRMD----SNVLFLKYEDMHRDLVTMVEQL 210 N+ LG+ SW E+V+ + E D ++VL ++YED+ D V ++ Sbjct: 156 ANEGLGWNALGAGGGVGLGSWPENVRSWTESSSDRFPNADVLTMRYEDLKGDPVARFSEI 215 Query: 211 ARFL 214 FL Sbjct: 216 VEFL 219 >3NIB-A nrPDB Length = 309 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/190 (25%), Positives = 85/190 (44%), Gaps = 36/190 (18%) Query: 49 WIVTYPKSGTSLLQEVVYLVSQGADPD-----EIGLMNIDEQLPVLEYPQPGLDIIKELT 103 WI +YPK+G + L+ ++ G P E + ++ L + + P E T Sbjct: 40 WIASYPKAGNTWLRCMLAAYITGKAPQTWKDMETVSLELEGMLHLGDMPP------TEPT 93 Query: 104 SPRLIKSHLPYRFLPSDLHN-GDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFC 162 P L+K+HL L++ +KV+Y+ RNP+D+++S ++R + E Sbjct: 94 KPVLVKTHLKADVPVLGLYSEATAKVLYLVRNPRDILLS------AMRMTAISRDDMESS 147 Query: 163 RRFMNDKLG--------------YGSWFEHVQEFWEHRMD----SNVLFLKYEDMHRDLV 204 R F D + GSW E+V+ + E D ++VL ++YED+ D V Sbjct: 148 RTFARDFIANEGLRMRGRGGGAGLGSWPENVRIWTESSRDRFPNADVLTMRYEDLKGDPV 207 Query: 205 TMVEQLARFL 214 ++ FL Sbjct: 208 ARFSEIVEFL 217 >4EEC-A nrPDB Length = 286 Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust. Identities = 47/195 (24%), Positives = 85/195 (43%), Gaps = 38/195 (19%) Query: 44 RPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELT 103 R S WI +YPK+G L+ ++ G +P E I +P LE ++++ Sbjct: 17 RGSMCWIASYPKAGGHWLRCMLTSYVTG-EPVET-WPGIQAGVPHLE------GLLRDGE 68 Query: 104 SPR-------LIKSHLPY-RFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYR 155 +P L+ +H R + +KV+ + RNP+D ++S +R Sbjct: 69 APSADPDEQVLLATHFTADRPVLRFYRESTAKVVCLIRNPRDAMLSL------MRMKGIP 122 Query: 156 GTFQEFCRR----FMNDK--------LGYGSWFEHVQEFWEHRMDS----NVLFLKYEDM 199 E CR+ F+ D+ G GSW E+++ + + +S VL ++YED+ Sbjct: 123 PEDVEACRKIAETFIADEGFSSVRIWAGEGSWPENIRSWTDSVHESFPNAAVLAVRYEDL 182 Query: 200 HRDLVTMVEQLARFL 214 +D + ++ FL Sbjct: 183 RKDPEGELWKVVDFL 197 >3RNL-A nrPDB Length = 311 Score = 34.7 bits (78), Expect = 0.047, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 8/103 (7%) Query: 125 DSKVIYMARNPKDLVVS-YYQFHRSLR-TMSYRGTFQEFCRRFMN--DKLGY----GSWF 176 D+K++ M RNP D S Y R R T+S+R + + R + L Y G + Sbjct: 109 DAKILIMLRNPVDRAFSAYMHLVRDERETLSFRESLAKEEERIRQHYEPLWYYRAVGLYA 168 Query: 177 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCD 219 V+ + + V + +E+ RD V +V FLGVS D Sbjct: 169 AQVKRYLDVFGREQVKVILFEEFARDPVQVVRDCCAFLGVSTD 211 >5KPS-A nrPDB Length = 750 Score = 30.8 bits (68), Expect = 0.67, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 19/88 (21%) Query: 215 GVSCDKAQLEALTE---HCHQLVDQCCNAEALPVG---------RGRVGLWKDIFTVSMN 262 G+S +A E L E H + + E+ G R GL +DI T+ N Sbjct: 636 GISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILAN 695 Query: 263 EKFDLV-------YKQKMGKCDLTFDFY 283 EK +++ KQ++ D+T + Y Sbjct: 696 EKVNVLGVASRSDTKQQLATIDMTIEIY 723 >5Y61-B nrPDB Length = 138 Score = 30.8 bits (68), Expect = 0.75, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 176 FEHVQEFWEHRMDSNVLFLKYED-MHRDLVTMVEQLAR-FLGVSCDKAQLEALTEH 229 FE E WE M S VLF D ++ D + ++AR L V DK +LE T++ Sbjct: 18 FELRDEGWEFGMSSKVLFGNNLDRLNPDSRNTLTKIARALLAVDIDKVRLEGHTDN 73 >4ZHW-A nrPDB Length = 168 Score = 30.4 bits (67), Expect = 0.84, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 176 FEHVQEFWEHRMDSNVLFLKYED-MHRDLVTMVEQLAR-FLGVSCDKAQLEALTEH 229 FE E WE M S VLF D ++ D + ++AR L V DK +LE T++ Sbjct: 48 FELRDEGWEFGMSSKVLFGNNLDRLNPDSRNTLTKIARALLAVDIDKVRLEGHTDN 103 >5L3P-z nrPDB Length = 819 Score = 30.4 bits (67), Expect = 0.88, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 7/46 (15%) Query: 245 VGRGRVGLWKDIFTVSMNEKFDLV-------YKQKMGKCDLTFDFY 283 V R GL +DI T+ NEK +++ KQ++ D+T + Y Sbjct: 747 VANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIY 792 >4LJI-A nrPDB Length = 141 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 111 HLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEF-CRRFMNDK 169 H+ LP+ L + K + A P+D + S F RS + SY G+ + + CRR D Sbjct: 51 HVGGSTLPNPLVSLSLKDLKGATPPRDTIASLVAFQRSPK--SYDGSEESYSCRRVSEDW 108 Query: 170 L 170 L Sbjct: 109 L 109 >1NST-A nrPDB Length = 325 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/103 (22%), Positives = 46/103 (44%), Gaps = 11/103 (10%) Query: 126 SKVIYMARNPKDLVVSYYQFHRSLRT-MSYRGTFQEFC----------RRFMNDKLGYGS 174 +KV+ + NP D S+YQ R+ ++ + TF E R N L G Sbjct: 140 AKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGW 199 Query: 175 WFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVS 217 + H++ + + +L L + + + +++ + +FLGV+ Sbjct: 200 YATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVT 242 >4GBM-A nrPDB Length = 323 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 55/231 (23%), Positives = 90/231 (38%), Gaps = 80/231 (34%) Query: 45 PSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNID------EQLPVLEYPQPGLD- 97 P ++I++ P+SG++LL+ ++ S P E+ L+ + EQL L Y GL Sbjct: 32 PGIIFILSSPRSGSTLLRVMLAGHSSLFSPPELHLLPFNTMKERQEQL-NLSYLGEGLQK 90 Query: 98 ---------------IIKELTS-----------------PRLIKSHLP-YRFLPSDLHNG 124 +IK+L S PRL+ P Y P+ L G Sbjct: 91 TFMEVKNLDATASQALIKDLESQNLSIQQVYGMLQENIAPRLLVDKSPTYAMEPTILERG 150 Query: 125 -----DSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYG--SWFE 177 +SK IY+ R+P ++ S F R M +G G + + Sbjct: 151 EALFANSKYIYLVRHPYSVIES-------------------FVRMRMQKLVGLGEENPYR 191 Query: 178 HVQEFWEHRMDSNVL-FL-----------KYEDMHRDLVTMVEQLARFLGV 216 ++ W + + N+L FL +YED+ + ++ QL FL V Sbjct: 192 VAEQVWA-KSNQNILNFLSQLEPERQHQIRYEDLVKKPQQVLSQLCDFLNV 241 >3WD0-A nrPDB Length = 503 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 5/56 (8%) Query: 136 KDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNV 191 DL VS+ + +++T + R F + C R M D YG F+ V WE+ + V Sbjct: 105 NDLGVSHANYVNAVKTPAARTKFAQSCVRIMKD---YG--FDGVDIDWEYPQAAEV 155 >4WVX-A nrPDB Length = 326 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 20/34 (58%) Query: 44 RPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEI 77 + + I+T+ + GT ++ YL+ GADP +I Sbjct: 169 KETGAVIITHTQEGTMGPEQAAYLLEHGADPKKI 202 >4ZGR-A nrPDB Length = 247 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 8/75 (10%) Query: 71 GADPDEIGLMNIDEQLPV-LEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVI 129 AD + + N+ +QL + Y G+ I+K + P + RFL DL NGD++ I Sbjct: 10 SADTYKSFIKNLRKQLTIGASYGSAGIPILKH-SVP------ICERFLLVDLTNGDNETI 62 Query: 130 YMARNPKDLVVSYYQ 144 +A N +D + Y+ Sbjct: 63 TLAINVEDAGFAAYR 77 >5TXK-A nrPDB Length = 372 Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 7/74 (9%) Query: 89 LEYPQPG-------LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVS 141 L +P PG LD++ SP + + Y KV+ +++ P L+++ Sbjct: 176 LAFPPPGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILT 235 Query: 142 YYQFHRSLRTMSYR 155 +F LRTM R Sbjct: 236 LLRFSFDLRTMRRR 249 >6IC4-G nrPDB Length = 257 Score = 27.3 bits (59), Expect = 8.2, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Query: 72 ADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRL 107 A EIG M EQL +E G+D +K++ SPRL Sbjct: 112 ALTAEIGSMKQSEQLASME--MIGVDPLKQIVSPRL 145 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1ZD1-A nrPDB 401 e-112 2REO-A nrPDB 377 e-105 3BFX-A nrPDB 375 e-104 3U3O-A nrPDB 373 e-104 1CJM-A nrPDB 370 e-103 2GWH-A nrPDB 365 e-101 2Z5F-A nrPDB 365 e-101 4JVN-A nrPDB 361 e-100 1AQU-A nrPDB 358 1e-99 2ZVQ-X nrPDB 353 6e-98 1Q22-A nrPDB 317 4e-87 1Q1Q-A nrPDB 314 3e-86 1OV4-A nrPDB 308 2e-84 5X2B-D nrPDB 278 2e-75 1Q44-A nrPDB 262 1e-70 5MEK-A nrPDB 261 2e-70 1X8L-A nrPDB 245 1e-65 3MGC-A nrPDB 174 4e-44 3NIB-A nrPDB 157 4e-39 Sequences not found previously or not previously below threshold: 4EEC-A nrPDB 117 5e-27 4GBM-A nrPDB 47 9e-06 4GOX-A nrPDB 43 2e-04 1T8T-A nrPDB 42 3e-04 3RNL-A nrPDB 40 0.001 1NST-A nrPDB 39 0.002 3K5T-A nrPDB 32 0.22 1ZRH-A nrPDB 32 0.24 1WZ2-A nrPDB 31 0.48 3AP1-A nrPDB 31 0.61 1WCZ-A nrPDB 30 1.2 4V0N-B nrPDB 29 1.9 1GA7-A nrPDB 29 2.4 1NP7-A nrPDB 29 3.0 >1ZD1-A nrPDB Length = 284 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 284/284 (100%), Positives = 284/284 (100%) Query: 1 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL 60 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL Sbjct: 1 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL 60 Query: 61 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD 120 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD Sbjct: 61 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD 120 Query: 121 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ 180 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ Sbjct: 121 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ 180 Query: 181 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA 240 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA Sbjct: 181 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA 240 Query: 241 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL Sbjct: 241 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 >2REO-A nrPDB Length = 305 Score = 377 bits (969), Expect = e-105, Method: Composition-based stats. Identities = 96/304 (31%), Positives = 155/304 (50%), Gaps = 20/304 (6%) Query: 1 MAESEAETPSTPGEFES-KYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTS 59 MA+ E P+ + E E GV + E++ANF +P D+ + TYPKSGT+ Sbjct: 2 MAKIEKNAPTMEKKPELFNIMEVDGVPTLILSKEWWEKVANFQAKPDDLILATYPKSGTT 61 Query: 60 LLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQP-----GLDIIKELTSPRLIKSHLPY 114 + E++ ++ D ++ ++ LE P L+ + E++SP+LIK+HLP Sbjct: 62 WMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPS 121 Query: 115 RFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGS 174 +P + + K++Y+ARNPKD +VSYY FHR M +EF +FM+ K+ GS Sbjct: 122 HLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGS 181 Query: 175 WFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH--- 231 WF+HV+ +W + +L+L YED+ +D +E++ +FL + L + H Sbjct: 182 WFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDV 241 Query: 232 QLVDQCCNAEALP-----------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 + N LP + +G G WK+ FTV+ NE+FD Y++KM LTF Sbjct: 242 MKQNPMTNYTTLPTSIMDHSISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTF 301 Query: 281 DFYL 284 + Sbjct: 302 RTEI 305 >3BFX-A nrPDB Length = 296 Score = 375 bits (963), Expect = e-104, Method: Composition-based stats. Identities = 92/285 (32%), Positives = 152/285 (53%), Gaps = 18/285 (6%) Query: 18 KYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEI 77 K E G L P +I +F +P D+ I TYPK+GT+ +QE+V ++ Q D ++ Sbjct: 12 KLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKC 71 Query: 78 GLMNIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMAR 133 I + P +E+ +P G++ K + SPR++K+HL + LP + K +Y+AR Sbjct: 72 QRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVAR 131 Query: 134 NPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLF 193 N KD +VSYY F R + GT++E+ F+N K+ +GSWF+HV+ +WE + +LF Sbjct: 132 NAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILF 191 Query: 194 LKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP------ 244 L YED+ RD + ++ +F+G D+ L+ + + + N + Sbjct: 192 LFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQ 251 Query: 245 -----VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G VG WK+ FTV+ NE+FD +Y++KM + F L Sbjct: 252 SISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFSMEL 296 >3U3O-A nrPDB Length = 315 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 94/281 (33%), Positives = 151/281 (53%), Gaps = 18/281 (6%) Query: 22 FHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMN 81 GV L + + + +F RP D+ I TYPKSGT+ + +++ ++ QG D ++ Sbjct: 35 VKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAP 94 Query: 82 IDEQLPVLEYPQPGL----DIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKD 137 I ++P LE+ PG+ + +K+ +PRL+K+HLP LP L + KV+Y+ARN KD Sbjct: 95 IFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKD 154 Query: 138 LVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYE 197 + VSYY F+ + GT+ F +FM ++ YGSW++HVQE+WE VL+L YE Sbjct: 155 VAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYE 214 Query: 198 DMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP---------- 244 DM + ++++ F+G S + ++ + +H + N +P Sbjct: 215 DMKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNYTTVPQEFMDHSISP 274 Query: 245 -VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G G WK FTV+ NE+FD Y +KM C L+F L Sbjct: 275 FMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 315 >1CJM-A nrPDB Length = 295 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 100/281 (35%), Positives = 151/281 (53%), Gaps = 18/281 (6%) Query: 22 FHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMN 81 GV L + + + +F RP D+ I TYPKSGT+ + +++ ++ QG D ++ Sbjct: 15 VKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAP 74 Query: 82 IDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKD 137 I ++P LE PG L+ +K+ PRLIKSHLP LP L + KV+Y+ARNPKD Sbjct: 75 IYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKD 134 Query: 138 LVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYE 197 + VSYY FHR + GT+ F +FM ++ YGSW++HVQE+WE VL+L YE Sbjct: 135 VAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYE 194 Query: 198 DMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP---------- 244 DM + ++++ F+G S + ++ + +H + N +P Sbjct: 195 DMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISP 254 Query: 245 -VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G G WK FTV+ NE+FD Y +KM C L+F L Sbjct: 255 FMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 >2GWH-A nrPDB Length = 298 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 97/281 (34%), Positives = 150/281 (53%), Gaps = 18/281 (6%) Query: 22 FHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMN 81 G+ P ++I NF +P D+ I TYPK+GT+ QE+V L+ D ++ Sbjct: 18 VKGILQPTDTCDIWDKIWNFQAKPDDLLISTYPKAGTTWTQEIVELIQNEGDVEKSKRAP 77 Query: 82 IDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKD 137 ++ P LE P GL+ + SPR++K+HLP+ LP L + K+IY+ARNPKD Sbjct: 78 THQRFPFLEMKIPSLGSGLEQAHAMPSPRILKTHLPFHLLPPSLLEKNCKIIYVARNPKD 137 Query: 138 LVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYE 197 +VSYY F R + + GT++E+ F+ K+ +GSW EHV+ +WE + +L+L YE Sbjct: 138 NMVSYYHFQRMNKALPAPGTWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKHRILYLFYE 197 Query: 198 DMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP---------- 244 DM ++ +++LA F+G D L+ + + + N ++P Sbjct: 198 DMKKNPKHEIQKLAEFIGKKLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAEIMDHSISP 257 Query: 245 -VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G VG WK FTV+ NE+FD YK+KM LTF F Sbjct: 258 FMRKGAVGDWKKHFTVAQNERFDEDYKKKMTDTRLTFHFQF 298 >2Z5F-A nrPDB Length = 298 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 93/282 (32%), Positives = 149/282 (52%), Gaps = 19/282 (6%) Query: 22 FHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMN 81 HG + E+I F RP D+ I TYPKSGT+ + E++ ++ D ++ Sbjct: 17 VHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDMILNDGDIEKCKRGF 76 Query: 82 IDEQLPVLEYPQPGL-----DIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPK 136 I E++P+LE PGL + +++ SPR++K+HLP LP + K+IY+ARN K Sbjct: 77 ITEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNCKMIYLARNAK 136 Query: 137 DLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKY 196 D+ VSYY F + GT++E+ +F+ K+ YGSWF HV+ +W+ + + +LFL Y Sbjct: 137 DVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKRKEEHPILFLYY 196 Query: 197 EDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP--------- 244 EDM + ++++ RFL + + L+ + H + N LP Sbjct: 197 EDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTTVMDHSKS 256 Query: 245 --VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G G WK+ FTV+ NEKFD +Y+ +M K L F + Sbjct: 257 PFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI 298 >4JVN-A nrPDB Length = 294 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 93/289 (32%), Positives = 149/289 (51%), Gaps = 18/289 (6%) Query: 14 EFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD 73 ++ K+ E HG+ + + + F RP D+ I TYPKSGT+ + E+VY++ + D Sbjct: 6 DYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGD 65 Query: 74 PDEIGLMNIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVI 129 ++ I ++P LE + G+ + E+ SPR++K+HLP LP+ D K+I Sbjct: 66 VEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKII 125 Query: 130 YMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDS 189 Y+ RN KD+ VS+Y F + G+F EF +FM ++ YGSW++HV+ +WE Sbjct: 126 YLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSP 185 Query: 190 NVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP-- 244 VLFL YED+ D+ V +L FL + ++ + H + N LP Sbjct: 186 RVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDE 245 Query: 245 ---------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G G WK+ FT ++NEKFD Y+Q+M + L F + Sbjct: 246 IMNQKLSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTEI 294 >1AQU-A nrPDB Length = 297 Score = 358 bits (919), Expect = 1e-99, Method: Composition-based stats. Identities = 95/289 (32%), Positives = 150/289 (51%), Gaps = 18/289 (6%) Query: 14 EFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD 73 E+ + EF GV + E++ F RP D+ I TYPKSGT+ + EVVY++ + D Sbjct: 9 EYYEVFGEFRGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGD 68 Query: 74 PDEIGLMNIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVI 129 ++ I ++P LE G+ +KE SPR++K+HLP + LP+ + K+I Sbjct: 69 VEKCKEDAIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMI 128 Query: 130 YMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDS 189 Y+ RN KD+ VSYY F + + +F EF +FM ++ YGSW++HV+ +WE +S Sbjct: 129 YLCRNAKDVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNS 188 Query: 190 NVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEALP-- 244 VLF+ YEDM D+ V +L FL ++ + +H + N +P Sbjct: 189 RVLFMFYEDMKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEE 248 Query: 245 ---------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G +G WK+ F ++ E+FD YKQ+M C + F L Sbjct: 249 MMNQKVSPFMRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKFRMEL 297 >2ZVQ-X nrPDB Length = 295 Score = 353 bits (905), Expect = 6e-98, Method: Composition-based stats. Identities = 87/288 (30%), Positives = 150/288 (52%), Gaps = 18/288 (6%) Query: 15 FESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADP 74 F + + G+ L ++ +F RP D+ I TYPKSGT+ + E++ L+ D Sbjct: 8 FRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDA 67 Query: 75 DEIGLMNIDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIY 130 ++ I +++P +E PG ++++ + SPR++K+HLP + LPS D K+IY Sbjct: 68 EKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIY 127 Query: 131 MARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSN 190 +ARN KD+VVSYY F++ + GT++EF +FM ++ +G W++HV+ +WE R + Sbjct: 128 VARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYR 187 Query: 191 VLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH---QLVDQCCNAEAL---- 243 +L+L YEDM + ++++ +FL + L + H + N + Sbjct: 188 ILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEE 247 Query: 244 -------PVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 284 + +G G WK+ FTV+ EKF+ Y +KM L F + Sbjct: 248 MDHSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI 295 >1Q22-A nrPDB Length = 299 Score = 317 bits (812), Expect = 4e-87, Method: Composition-based stats. Identities = 91/291 (31%), Positives = 146/291 (50%), Gaps = 22/291 (7%) Query: 2 AESEAETPSTPGEFESKYFEFHGVRLPP--FCRGKMEEIAN-FPVRPSDVWIVTYPKSGT 58 ++ + PGE YF + GV P + + N VR D++I+TYPKSGT Sbjct: 5 SDISEISQKLPGE----YFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGT 60 Query: 59 SLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLP 118 + + E++ L+ + DP I + I E+ P E G + + SPRL+ SHLP + Sbjct: 61 TWMIEIICLILKEGDPSWIRSVPIWERAPWCETIV-GAFSLPDQYSPRLMSSHLPIQIFT 119 Query: 119 SDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEH 178 + +KVIYM RNP+D+VVS Y + + + GT +F R F+ ++ +GSWF+H Sbjct: 120 KAFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDH 179 Query: 179 VQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEH---CHQLVD 235 ++ + + N LF+ YE++ +DL VE++ FLG K L ++ H + Sbjct: 180 IKGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKAN 239 Query: 236 QCCNAEALP-----------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGK 275 N LP + +G G WK+ FTV+ +E FD Y+++M Sbjct: 240 TMSNYTLLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRG 290 >1Q1Q-A nrPDB Length = 350 Score = 314 bits (804), Expect = 3e-86, Method: Composition-based stats. Identities = 89/284 (31%), Positives = 143/284 (50%), Gaps = 18/284 (6%) Query: 9 PSTPGEFESKYFEFHGVRLPP--FCRGKMEEIAN-FPVRPSDVWIVTYPKSGTSLLQEVV 65 P + +YF + GV P + + N VR D++I+TYPKSGT+ + E++ Sbjct: 6 PFHSQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEII 65 Query: 66 YLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGD 125 L+ + DP I + I E+ P E G + + SPRL+ SHLP + + Sbjct: 66 CLILKEGDPSWIRSVPIWERAPWCETIV-GAFSLPDQYSPRLMSSHLPIQIFTKAFFSSK 124 Query: 126 SKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEH 185 +KVIYM RNP+D+VVS Y + + + GT +F R F+ ++ +GSWF+H++ + Sbjct: 125 AKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRM 184 Query: 186 RMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEH---CHQLVDQCCNAEA 242 + N LF+ YE++ +DL VE++ FLG K L ++ H + N Sbjct: 185 KGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTL 244 Query: 243 LP-----------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGK 275 LP + +G G WK+ FTV+ +E FD Y+++M Sbjct: 245 LPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRG 288 >1OV4-A nrPDB Length = 293 Score = 308 bits (790), Expect = 2e-84, Method: Composition-based stats. Identities = 84/283 (29%), Positives = 144/283 (50%), Gaps = 17/283 (6%) Query: 9 PSTPGEFESKYFEFHGVRLPP--FCRGKMEEIAN-FPVRPSDVWIVTYPKSGTSLLQEVV 65 P + F G+ P F + ++ + F +R DV I+TYPKSGT+ L E++ Sbjct: 3 PRNSRVDSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEIL 62 Query: 66 YLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGD 125 L+ D I + I E+ P +E + G + E SPRL SHLP + P + Sbjct: 63 CLMHSKGDAKWIQSVPIWERSPWVE-SEIGYTALSETESPRLFSSHLPIQLFPKSFFSSK 121 Query: 126 SKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEH 185 +KVIY+ RNP+D++VS Y F ++++ + +++E+ F + YGSWF+H+ + Sbjct: 122 AKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPM 181 Query: 186 RMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEA 242 R + N L L YE++ +D +E++ +FLG + + +L + ++ ++ N Sbjct: 182 REEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSL 241 Query: 243 LPV----------GRGRVGLWKDIFTVSMNEKFDLVYKQKMGK 275 L V +G G WK+ FTV+ E FD ++++KM Sbjct: 242 LSVDYVVDKTQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 284 >5X2B-D nrPDB Length = 281 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 125/267 (46%), Gaps = 33/267 (12%) Query: 32 RGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGA----DPDEIGLMNIDEQLP 87 + + +F R D+++V+YPKSGT L EV+ + P E+G ++ E+ Sbjct: 17 EELLGSLDSFDAREDDIFLVSYPKSGTHWLAEVIERIPDAGITLTSPIELGDISKFEE-- 74 Query: 88 VLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHR 147 +K + R I +HL Y LP + K+IY+ RNPKD VS + ++R Sbjct: 75 -----------LKRIPKRRAIPTHLNYEMLPVTVKQKQCKIIYIVRNPKDTAVSMFHYYR 123 Query: 148 SLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMV 207 + T+ F F+ + YGSWF+HV + EH+ D NVLF+ YE+M +D V + Sbjct: 124 DNPNLPSTETWAAFLELFLKGDVVYGSWFDHVLSWEEHKNDKNVLFIFYEEMKKDFVKSL 183 Query: 208 EQLARFLGVSCDKAQLEALTEHCH----------------QLVDQCCNAEALPVGRGRVG 251 +++ FLG+ + +++ + ++ + L +G VG Sbjct: 184 KKITAFLGIDVNDSEMAKIARSTSFSEMKSNAAKENCDPNHVICALTSDRNLVFRKGVVG 243 Query: 252 LWKDIFTVSMNEKFDLVYKQKMGKCDL 278 W + FT N FD ++ +KM D+ Sbjct: 244 DWINYFTPKQNRGFDELFTEKMRNSDV 270 >1Q44-A nrPDB Length = 326 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 76/304 (25%), Positives = 131/304 (43%), Gaps = 37/304 (12%) Query: 9 PSTPGEFESKYFEFHGV-RLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYL 67 P G S+ +EF G+ +G + F + SD+ +VT PKSGT+ L+ +V+ Sbjct: 28 PKEKGWLVSEIYEFQGLWHTQAILQGILICQKRFEAKDSDIILVTNPKSGTTWLKALVFA 87 Query: 68 VSQ---------GADPDEIGLMNIDEQLPVLE---YPQPGLDIIKELTSPRLIKSHLPYR 115 + G P + + N +P LE Y P D L SPRL+ +H+ + Sbjct: 88 LLNRHKFPVSSSGNHP--LLVTNPHLLVPFLEGVYYESPDFDF-SSLPSPRLMNTHISHL 144 Query: 116 FLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSL---RTMSYRGTFQEFCRRFMNDKLGY 172 LP + + K++Y RNPKD+ VS + F + L T Y ++ F K Sbjct: 145 SLPESVKSSSCKIVYCCRNPKDMFVSLWHFGKKLAPEETADYP--IEKAVEAFCEGKFIG 202 Query: 173 GSWFEHVQEFWEHRMDSN--VLFLKYEDMHRDLVTMVEQLARFLGVS------------- 217 G +++H+ E+W ++ VLF+ YE++ + ++++A FL Sbjct: 203 GPFWDHILEYWYASRENPNKVLFVTYEELKKQTEVEMKRIAEFLECGFIEEEEVREIVKL 262 Query: 218 CDKAQLEALTEHCHQLVDQCCNAEALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCD 277 C L L + + + +G +G W+D + S+ E+ D ++K Sbjct: 263 CSFESLSNLEVNKEGKLPNGIETKTF-FRKGEIGGWRDTLSESLAEEIDRTIEEKFKGSG 321 Query: 278 LTFD 281 L F Sbjct: 322 LKFS 325 >5MEK-A nrPDB Length = 322 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 75/302 (24%), Positives = 127/302 (42%), Gaps = 33/302 (10%) Query: 9 PSTPGE-FESKYFEFHGVR-LPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVY 66 P G + E+ G LP G + F RPSD + +YPK+GT+ L+ + + Sbjct: 20 PHEKGWRPKEPLIEYGGYWWLPSLLEGCIHAQEFFQARPSDFLVCSYPKTGTTWLKALTF 79 Query: 67 LVSQGADPDE----IGLMNIDEQLPVLEYPQP---GLDIIKELTSPRLIKSHLPYRFLPS 119 ++ + D+ + N E +P +E P +D++K+ + L +H+PY LP Sbjct: 80 AIANRSRFDDSSNPLLKRNPHEFVPYIEIDFPFFPEVDVLKDKGN-TLFSTHIPYELLPD 138 Query: 120 DLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYR-GTFQEFCRRFMNDKLGYGSWFEH 178 + K++Y+ R PKD +S + F RT +E F GYG + H Sbjct: 139 SVVKSGCKMVYIWREPKDTFISMWTFLHKERTELGPVSNLEESFDMFCRGLSGYGPYLNH 198 Query: 179 VQEFWEHRMDS--NVLFLKYEDMHRDLVTMVEQLARFLGVS-----------------CD 219 + +W+ ++ +LFLKYE M D + V+ LA F+G C Sbjct: 199 ILAYWKAYQENPDRILFLKYETMRADPLPYVKSLAEFMGHGFTAEEEEKGVVEKVVNLCS 258 Query: 220 KAQLEALTEHCHQL---VDQCCNAEALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKC 276 L+ L + + A + +G+VG W + T M + D + ++K Sbjct: 259 FETLKNLEANKGEKDREDRPGVYANSAYFRKGKVGDWSNYLTPEMAARIDGLMEEKFKGT 318 Query: 277 DL 278 L Sbjct: 319 GL 320 >1X8L-A nrPDB Length = 351 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 79/308 (25%), Positives = 141/308 (45%), Gaps = 52/308 (16%) Query: 23 HGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGA---------- 72 G + I N P+RP+DV++ +Y +SGT++ QE+V+L+ Sbjct: 41 KGYMVYRPYLKDAANIYNMPLRPTDVFVASYQRSGTTMTQELVWLIENDLNFEAAKTYMS 100 Query: 73 ------------DPDEIGLMN----------IDEQLPVLEYP-QPGLDIIKELT--SPRL 107 DP++ N ++ L +LEY +PG ++ + R Sbjct: 101 LRYIYLDGFMIYDPEKQEEYNDILPNPENLDMERYLGLLEYSSRPGSSLLAAVPPTEKRF 160 Query: 108 IKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMN 167 +K+HLP +P ++ + K++Y+AR+P+D+ VS + R L ++ + F++F F Sbjct: 161 VKTHLPLSLMPPNMLD-TVKMVYLARDPRDVAVSSFHHARLLYLLNKQSNFKDFWEMFHR 219 Query: 168 DKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALT 227 +FEHV+E W R D N+LFL YED +DL + ++A FLG + Q++ L+ Sbjct: 220 GLYTLTPYFEHVKEAWAKRHDPNMLFLFYEDYLKDLPGSIARIADFLGKKLSEEQIQRLS 279 Query: 228 EHCHQ---------------LVDQCCNAEALPVGRGRVGLWKDIFTVSMNEKFDLVYKQK 272 EH + + + E + +G+ G W+D F M ++ + K Sbjct: 280 EHLNFEKFKNNGAVNMEDYREIGILADGEHF-IRKGKAGCWRDYFDEEMTKQAEKWIKDN 338 Query: 273 MGKCDLTF 280 + DL + Sbjct: 339 LKDTDLRY 346 >3MGC-A nrPDB Length = 319 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 61/277 (22%), Positives = 108/277 (38%), Gaps = 47/277 (16%) Query: 49 WIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDI-IKELTSPRL 107 WI +YPK+G + ++ ++ G P +ID + LE D+ E P L Sbjct: 40 WIASYPKAGNTWVRCMLAAYITGKAPQ--VWNDIDAESLTLEAMLRFGDLPPAEPMEPVL 97 Query: 108 IKSHLPYRFLPSDLH-NGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFM 166 +K+HL L+ +KV+Y+ RNP+D+++S + R + ++F R+F+ Sbjct: 98 VKTHLKADVPVLGLYGEATAKVLYLVRNPRDMLLSSMRMASISRDDVEKS--RDFARKFI 155 Query: 167 -NDKLGYG-----------SWFEHVQEFWEHRMD----SNVLFLKYEDMHRDLVTMVEQL 210 N+ LG+ SW E+V+ + E D ++VL ++YED+ D V ++ Sbjct: 156 ANEGLGWNALGAGGGVGLGSWPENVRSWTESSSDRFPNADVLTMRYEDLKGDPVARFSEI 215 Query: 211 ARF--LGVSCDKAQLEALTEHC------HQLVDQCCNAEALPVG-------RGRVGLWKD 255 F LG D + P+ +G G + Sbjct: 216 VEFLDLGGPVDIEDIRRAVAASTLERMRELEKRSEQQGGGSPIRHGDARMMKGGPGGARP 275 Query: 256 IFTVS---------MNEKFDLVYKQKMGKCDLTFDFY 283 F + E + Y++ + D F Y Sbjct: 276 QFVGEGRYDQSLSFLGEDIESDYQELLHG-DSGFALY 311 >3NIB-A nrPDB Length = 309 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 52/211 (24%), Positives = 88/211 (41%), Gaps = 38/211 (18%) Query: 49 WIVTYPKSGTSLLQEVVYLVSQGADPD-----EIGLMNIDEQLPVLEYPQPGLDIIKELT 103 WI +YPK+G + L+ ++ G P E + ++ L + + P E T Sbjct: 40 WIASYPKAGNTWLRCMLAAYITGKAPQTWKDMETVSLELEGMLHLGDMP------PTEPT 93 Query: 104 SPRLIKSHLPYRFLPSDLH-NGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFC 162 P L+K+HL L+ +KV+Y+ RNP+D+++S ++R + E Sbjct: 94 KPVLVKTHLKADVPVLGLYSEATAKVLYLVRNPRDILLS------AMRMTAISRDDMESS 147 Query: 163 RRFMNDKLG--------------YGSWFEHVQEFWEHRMD----SNVLFLKYEDMHRDLV 204 R F D + GSW E+V+ + E D ++VL ++YED+ D V Sbjct: 148 RTFARDFIANEGLRMRGRGGGAGLGSWPENVRIWTESSRDRFPNADVLTMRYEDLKGDPV 207 Query: 205 TMVEQLARF--LGVSCDKAQLEALTEHCHQL 233 ++ F LG D + C Sbjct: 208 ARFSEIVEFLDLGDPVDIEDIRRAVAACTLE 238 >4EEC-A nrPDB Length = 286 Score = 117 bits (294), Expect = 5e-27, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 80/204 (39%), Gaps = 20/204 (9%) Query: 49 WIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIK-ELTSPRL 107 WI +YPK+G L+ ++ G + I +P LE + + L Sbjct: 22 WIASYPKAGGHWLRCMLTSYVTGEPVE--TWPGIQAGVPHLEGLLRDGEAPSADPDEQVL 79 Query: 108 IKSHLPYRFLPSDLH-NGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYR-GTFQEFCRRF 165 + +H + +KV+ + RNP+D ++S R ++ F Sbjct: 80 LATHFTADRPVLRFYRESTAKVVCLIRNPRDAMLSLM---RMKGIPPEDVEACRKIAETF 136 Query: 166 MNDK--------LGYGSWFEHVQEFW----EHRMDSNVLFLKYEDMHRDLVTMVEQLARF 213 + D+ G GSW E+++ + E ++ VL ++YED+ +D + ++ F Sbjct: 137 IADEGFSSVRIWAGEGSWPENIRSWTDSVHESFPNAAVLAVRYEDLRKDPEGELWKVVDF 196 Query: 214 LGVSCDKAQLEALTEHCHQLVDQC 237 L + +A+ + + + Sbjct: 197 LELGGRDGVADAVANCTLERMREM 220 >4GBM-A nrPDB Length = 323 Score = 46.9 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 41/224 (18%), Positives = 82/224 (36%), Gaps = 50/224 (22%) Query: 45 PSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMN---IDEQLPVLEYPQPG------ 95 P ++I++ P+SG++LL+ ++ S P E+ L+ + E+ L G Sbjct: 32 PGIIFILSSPRSGSTLLRVMLAGHSSLFSPPELHLLPFNTMKERQEQLNLSYLGEGLQKT 91 Query: 96 -----------------------------LDIIKELTSPRLIKSHLPYRFLPSDLHN--- 123 +++E +PRL+ P + + Sbjct: 92 FMEVKNLDATASQALIKDLESQNLSIQQVYGMLQENIAPRLLVDKSPTYAMEPTILERGE 151 Query: 124 ---GDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ 180 +SK IY+ R+P ++ S F R R G +E + + + +++ Sbjct: 152 ALFANSKYIYLVRHPYSVIES---FVRM-RMQKLVGLGEE--NPYRVAEQVWAKSNQNIL 205 Query: 181 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLE 224 F ++YED+ + ++ QL FL V + L+ Sbjct: 206 NFLSQLEPERQHQIRYEDLVKKPQQVLSQLCDFLNVPFEPELLQ 249 >4GOX-A nrPDB Length = 313 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 39/100 (39%), Gaps = 6/100 (6%) Query: 125 DSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWE 184 +K I++ R+P ++ S+ + + + + + ++ + Sbjct: 148 QAKYIHLVRHPYAVIESFTRLRMDKLLGAEQQNPYALAES------IWRTSNRNILDLGR 201 Query: 185 HRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLE 224 L + YED+ RD ++ + FLGV D+A L Sbjct: 202 TVGADRYLQVIYEDLVRDPRKVLTNICDFLGVDFDEALLN 241 >1T8T-A nrPDB Length = 271 Score = 42.3 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 25/125 (20%), Positives = 47/125 (37%), Gaps = 17/125 (13%) Query: 120 DLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSW---- 175 + D+K+I + R+P +S Y S R TF+ + L SW Sbjct: 95 SAMSKDTKLIVVVRDPVTRAISDYTQTLSKR--PDIPTFESLTFKNRTAGLIDTSWSAIQ 152 Query: 176 ----FEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH 231 +H++ + H +LF+ E + D + ++ FLG L+ + H Sbjct: 153 IGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLG-------LKRIITDKH 205 Query: 232 QLVDQ 236 ++ Sbjct: 206 FYFNK 210 >3RNL-A nrPDB Length = 311 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 48/125 (38%), Gaps = 8/125 (6%) Query: 125 DSKVIYMARNPKDLVVS-YYQFHRSLR-TMSYRGTFQEFCRRFMNDKLGY------GSWF 176 D+K++ M RNP D S Y R R T+S+R + + R G + Sbjct: 109 DAKILIMLRNPVDRAFSAYMHLVRDERETLSFRESLAKEEERIRQHYEPLWYYRAVGLYA 168 Query: 177 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQ 236 V+ + + V + +E+ RD V +V FLGVS D ++ + + Sbjct: 169 AQVKRYLDVFGREQVKVILFEEFARDPVQVVRDCCAFLGVSTDFVPDTSIRHNESGVPKS 228 Query: 237 CCNAE 241 Sbjct: 229 RSLYN 233 >1NST-A nrPDB Length = 325 Score = 39.2 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 37/213 (17%), Positives = 74/213 (34%), Gaps = 24/213 (11%) Query: 28 PPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYL-------VSQGADPDEIGLM 80 + + P + I+ K+GT+ L + + +EI Sbjct: 31 DKRHKDIWSKEKTCDRFPK-LLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFF 89 Query: 81 NIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPY---RFLP--SDLHNGDSKVIYMARNP 135 N +++ I TS + Y P + +KV+ + NP Sbjct: 90 NGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINP 149 Query: 136 KDLVVSYYQFHRSLRT-MSYRGTFQEF----------CRRFMNDKLGYGSWFEHVQEFWE 184 D S+YQ R+ ++ + TF E R N L G + H++ + Sbjct: 150 ADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLS 209 Query: 185 HRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVS 217 + +L L + + + +++ + +FLGV+ Sbjct: 210 AYHANQILVLDGKLLRTEPAKVMDMVQKFLGVT 242 >3K5T-A nrPDB Length = 731 Score = 32.3 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 29/76 (38%), Gaps = 7/76 (9%) Query: 59 SLLQEVVYLVSQG---ADPDEIGLMNIDEQLPV--LEYPQPGLDIIKELTSPRLIKSHLP 113 E V+ G P+E+ D ++ V LE P PG P L SH P Sbjct: 210 HWAVEQVW--YNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKP 267 Query: 114 YRFLPSDLHNGDSKVI 129 PS +H +++ Sbjct: 268 RGDFPSPIHVSGPRLV 283 >1ZRH-A nrPDB Length = 274 Score = 32.3 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 30/183 (16%), Positives = 70/183 (38%), Gaps = 22/183 (12%) Query: 49 WIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLP-------VLEYPQPGLDIIKE 101 I+ K GT L E++ L A + E+ + + P + Sbjct: 25 IIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTV 84 Query: 102 LTSPRLIKSHLPYRFLPSDLHNGD--SKVIYMARNPKDLVVSYY---QFHRSLRTMSYRG 156 +P S +P +++ + +++ + R+P + V+S Y ++ + Y Sbjct: 85 EKTPAYFTS----PKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYP- 139 Query: 157 TFQEFCRRFMNDKLGYGS-----WFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLA 211 + +EF R + Y + + H+Q + ++ + + + RD ++++ Sbjct: 140 SIEEFLVRDGRLNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVE 199 Query: 212 RFL 214 RFL Sbjct: 200 RFL 202 >1WZ2-A nrPDB Length = 967 Score = 31.1 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 21/153 (13%), Positives = 46/153 (30%), Gaps = 35/153 (22%) Query: 130 YMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFM-NDKLGYGSWFEHVQEFWEHRMD 188 Y+ R D+ V + +E + + W E V+E+W ++ Sbjct: 781 YVLRTLADVWVRL-----MAPFTPH--ICEELWEKLGGEGFVSLAKWPEPVEEWWNETIE 833 Query: 189 SNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNAEALPVGRG 248 + E+ R ++ ++++ V + NA+ + Sbjct: 834 AE------EEFIRSVMEDIKEIIE---------------------VAKIENAKRAYIYTA 866 Query: 249 RVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFD 281 WK VS F ++ M ++ Sbjct: 867 EDWKWKVAEVVSEKRDFKSSMEELMKDSEIRKH 899 >3AP1-A nrPDB Length = 337 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 31/208 (14%), Positives = 69/208 (33%), Gaps = 45/208 (21%) Query: 48 VWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNI------------DEQLPVLEYPQPG 95 +++ P+SGT+L++ ++ + +E ++ E+L + E Sbjct: 49 IFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTD 108 Query: 96 LDIIKELTS---PRLIKSHLPYRFL----PSDLHNGDSKVIYMAR---NPKDLVVSYYQF 145 + + + + K P R L P L + +Y++R N K F Sbjct: 109 EVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSS----VYLSRLFPNSK--------F 156 Query: 146 HRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRM----------DSNVLFLK 195 +R R+ S+ + + ++ + L + Sbjct: 157 LLMVRD-GRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVY 215 Query: 196 YEDMHRDLVTMVEQLARFLGVSCDKAQL 223 YE + ++ + FLG++ A L Sbjct: 216 YEQLVLHPRRSLKLILDFLGIAWSDAVL 243 >1WCZ-A nrPDB Length = 268 Score = 30.0 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 26/81 (32%), Gaps = 4/81 (4%) Query: 53 YPKSGTSLLQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELT--SPRLIKS 110 YP G + E + S D + ++ + E +P T + + + Sbjct: 75 YPNGGFT--AEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVT 132 Query: 111 HLPYRFLPSDLHNGDSKVIYM 131 P + + K+ Y+ Sbjct: 133 GYPGDKPVATMWESKGKITYL 153 >4V0N-B nrPDB Length = 425 Score = 29.2 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 17/89 (19%) Query: 85 QLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQ 144 + P+L+ P I E T+PRL L IY+ RN + YY+ Sbjct: 91 EHPLLDTPVAICSYISENTAPRL-----------PALAVAAGSHIYIYRNLR----PYYK 135 Query: 145 FHRSLRTMSYRGTFQEFCRRFMNDKLGYG 173 F ++ Q+ ++ M ++ G Sbjct: 136 FVLPPENVNTEE--QDIWQKVMEGEIVIG 162 >1GA7-A nrPDB Length = 209 Score = 28.8 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 34/89 (38%), Gaps = 7/89 (7%) Query: 17 SKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVY-LVSQGADPD 75 + H L PF + + + V + I Y S T L E+V ++ +G + Sbjct: 52 EIFERGHAAVLLPF-----DPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEGESVE 106 Query: 76 EIGLMNIDEQLPVL-EYPQPGLDIIKELT 103 ++ E+ ++ + +P L + Sbjct: 107 DVARREAIEEAGLIVKRTKPVLSFLASPG 135 >1NP7-A nrPDB Length = 489 Score = 28.8 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 20/39 (51%) Query: 96 LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARN 134 + ++++ + L+ + LP + +P ++K IY R Sbjct: 71 AESLQKVGNKLLVTTGLPEQVIPQIAKQINAKTIYYHRE 109 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.139 0.405 Lambda K H 0.267 0.0423 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,995,469 Number of Sequences: 36641 Number of extensions: 490413 Number of successful extensions: 1418 Number of sequences better than 10.0: 35 Number of HSP's better than 10.0 without gapping: 44 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1265 Number of HSP's gapped (non-prelim): 77 length of query: 284 length of database: 10,336,785 effective HSP length: 96 effective length of query: 188 effective length of database: 6,819,249 effective search space: 1282018812 effective search space used: 1282018812 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)