BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9BPX1 (270 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5JS6-A nrPDB 548 e-156 1GEE-A nrPDB 145 2e-35 3AUT-A nrPDB 144 4e-35 4MOW-A nrPDB 133 7e-32 5ITV-A nrPDB 133 1e-31 1NFF-A nrPDB 127 4e-30 4NBT-A nrPDB 123 7e-29 3RSH-A nrPDB 122 2e-28 4JRO-A nrPDB 121 3e-28 4AVY-A nrPDB 120 6e-28 2HSD-A nrPDB 120 7e-28 5T5Q-A nrPDB 119 2e-27 1HXH-A nrPDB 118 3e-27 6CI9-A nrPDB 118 3e-27 1AE1-A nrPDB 117 5e-27 3FTP-A nrPDB 117 6e-27 3OSU-A nrPDB 117 7e-27 1K2W-A nrPDB 115 2e-26 5U9P-A nrPDB 115 2e-26 4GKB-A nrPDB 114 4e-26 4E6P-A nrPDB 113 8e-26 1Q7C-A nrPDB 113 1e-25 1AHH-A nrPDB 111 3e-25 1YXM-A nrPDB 111 3e-25 5CDY-A nrPDB 111 3e-25 2AE2-A nrPDB 110 5e-25 4M8S-A nrPDB 110 8e-25 4NBV-A nrPDB 109 1e-24 4CQM-B nrPDB 109 1e-24 3UN1-A nrPDB 108 2e-24 1X1T-A nrPDB 108 2e-24 2NM0-A nrPDB 108 3e-24 2HQ1-A nrPDB 108 4e-24 4DBZ-A nrPDB 107 4e-24 5OJG-A nrPDB 107 4e-24 2AG5-A nrPDB 107 5e-24 3F9I-A nrPDB 107 6e-24 4FC7-A nrPDB 107 7e-24 2EW8-A nrPDB 106 8e-24 2PNF-A nrPDB 106 9e-24 1GEG-A nrPDB 106 1e-23 4DMM-A nrPDB 106 1e-23 5JY1-A nrPDB 105 2e-23 2O23-A nrPDB 105 2e-23 3EMK-A nrPDB 103 6e-23 5IZ4-A nrPDB 103 1e-22 2BGM-A nrPDB 102 2e-22 1E3W-A nrPDB 101 3e-22 2CDH-G nrPDB 101 3e-22 4BO1-A nrPDB 101 3e-22 4RZI-B nrPDB 101 4e-22 2UVD-A nrPDB 101 4e-22 3GRP-A nrPDB 100 5e-22 4RZH-A nrPDB 100 6e-22 4IIN-A nrPDB 99 1e-21 3W8F-A nrPDB 98 3e-21 2B4Q-A nrPDB 97 9e-21 3WOH-A nrPDB 97 1e-20 1BDB-A nrPDB 97 1e-20 2CFC-A nrPDB 96 1e-20 2GDZ-A nrPDB 96 2e-20 3PPI-A nrPDB 96 2e-20 5VT6-A nrPDB 96 2e-20 2Q2Q-A nrPDB 95 3e-20 3O4R-A nrPDB 94 6e-20 4CQL-A nrPDB 94 8e-20 4K6F-A nrPDB 93 1e-19 4KMS-A nrPDB 93 1e-19 2ZAT-A nrPDB 93 2e-19 3R3S-A nrPDB 92 2e-19 3ZV3-A nrPDB 92 2e-19 3LYL-A nrPDB 92 2e-19 1CYD-A nrPDB 92 3e-19 4IS3-A nrPDB 92 3e-19 3WYE-A nrPDB 92 3e-19 2C07-A nrPDB 91 4e-19 5YSS-A nrPDB 91 4e-19 3V2G-A nrPDB 91 5e-19 3V2H-A nrPDB 90 9e-19 1O5I-A nrPDB 90 1e-18 3EZL-A nrPDB 88 4e-18 3RWB-A nrPDB 88 4e-18 3D3W-A nrPDB 88 4e-18 2PH3-A nrPDB 88 4e-18 3UF0-A nrPDB 88 4e-18 5B1Y-A nrPDB 88 4e-18 6NRP-A nrPDB 87 7e-18 3WTC-A nrPDB 87 8e-18 2FWM-X nrPDB 87 9e-18 1DOH-A nrPDB 87 1e-17 1UZM-A nrPDB 86 2e-17 3VZS-A nrPDB 86 2e-17 3A28-C nrPDB 85 3e-17 4Z9Y-A nrPDB 84 5e-17 4CR6-A nrPDB 84 6e-17 3T7C-A nrPDB 84 9e-17 5OVJ-A nrPDB 84 9e-17 5OVL-A nrPDB 83 1e-16 3KZV-A nrPDB 82 3e-16 3U5T-A nrPDB 82 3e-16 3UVE-A nrPDB 81 5e-16 1H5Q-A nrPDB 80 9e-16 4IIV-A nrPDB 80 1e-15 3GDF-A nrPDB 79 2e-15 1W73-A nrPDB 79 2e-15 5O3Z-A nrPDB 78 5e-15 4DRY-A nrPDB 76 1e-14 5EJ2-A nrPDB 75 2e-14 3PXX-A nrPDB 75 4e-14 3RKU-A nrPDB 74 5e-14 4EGF-A nrPDB 74 6e-14 2P91-A nrPDB 74 6e-14 4RGB-A nrPDB 74 8e-14 3OML-A nrPDB 72 2e-13 4HP8-A nrPDB 71 4e-13 3OEC-A nrPDB 70 7e-13 4DA9-A nrPDB 70 1e-12 4TRR-A nrPDB 68 4e-12 5TF4-A nrPDB 67 6e-12 2X9N-A nrPDB 67 8e-12 3OIC-A nrPDB 65 2e-11 3V8B-A nrPDB 65 4e-11 5ILO-A nrPDB 64 5e-11 5PGZ-A nrPDB 62 2e-10 5YCX-A nrPDB 62 4e-10 2PD3-A nrPDB 61 6e-10 3U4C-A nrPDB 60 1e-09 3GRK-A nrPDB 58 4e-09 5KOI-A nrPDB 58 4e-09 4M89-A nrPDB 58 5e-09 3UCF-A nrPDB 58 5e-09 3K2E-A nrPDB 57 6e-09 1SNY-A nrPDB 57 9e-09 3DWF-A nrPDB 56 2e-08 1FJH-A nrPDB 56 2e-08 2YW9-A nrPDB 55 3e-08 3U9L-A nrPDB 55 3e-08 2DKN-A nrPDB 55 4e-08 3O26-A nrPDB 54 9e-08 2NWQ-A nrPDB 53 1e-07 3BHI-A nrPDB 53 2e-07 4JQC-A nrPDB 52 3e-07 1N5D-A nrPDB 52 3e-07 4ALL-A nrPDB 52 3e-07 5CFZ-A nrPDB 52 3e-07 5TQV-A nrPDB 51 5e-07 3E9N-A nrPDB 50 7e-07 2BFA-A nrPDB 50 1e-06 2QHX-A nrPDB 50 1e-06 5L51-A nrPDB 49 3e-06 5LCX-A nrPDB 48 4e-06 2HRB-A nrPDB 47 1e-05 4HBG-A nrPDB 44 7e-05 5WQO-A nrPDB 43 2e-04 4Q9N-A nrPDB 42 4e-04 1P33-A nrPDB 41 5e-04 1B15-A nrPDB 39 0.002 2O2S-A nrPDB 38 0.006 1BXK-A nrPDB 36 0.015 5Y28-A nrPDB 35 0.048 3ORF-A nrPDB 35 0.048 5Y2D-A nrPDB 34 0.057 3OND-A nrPDB 34 0.075 3NJ4-A nrPDB 33 0.13 3H9U-A nrPDB 32 0.22 2PTG-A nrPDB 32 0.22 1OC2-A nrPDB 31 0.57 3N58-A nrPDB 30 1.00 3GIU-A nrPDB 30 1.00 4LAT-A nrPDB 30 1.6 5JXW-A nrPDB 29 1.8 5INF-A nrPDB 28 3.8 1KEU-A nrPDB 28 5.2 6GBN-A nrPDB 28 6.1 3I6T-A nrPDB 27 6.3 4KUG-A nrPDB 27 7.7 2Q1W-A nrPDB 27 8.1 >5JS6-A nrPDB Length = 274 Score = 548 bits (1411), Expect = e-156, Method: Compositional matrix adjust. Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL Sbjct: 3 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 62 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT Sbjct: 63 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 122 Query: 121 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN Sbjct: 123 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 182 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG 240 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG Sbjct: 183 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG 242 Query: 241 IELLVTGGAELGYGCKASRSTPVDAPDIPS 270 IELLVTGGAELGYGCKASRSTPVDAPDIPS Sbjct: 243 IELLVTGGAELGYGCKASRSTPVDAPDIPS 272 >1GEE-A nrPDB Length = 261 Score = 145 bits (365), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 13/259 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVIC--DKDESGGRALEQ--ELPG-AVFILCDV 63 GKVVV+TG G+G + F A+VV+ K++ LE+ ++ G A+ + DV Sbjct: 7 GKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDV 66 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 T E DV LV I+ FG+LD ++NNAG P E S + ++++ NL G + ++ Sbjct: 67 TVESDVINLVQSAIKEFGKLDVMINNAGLENPVSS-HEMSLSDWNKVIDTNLTGAFLGSR 125 Query: 124 LALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 A+ Y ++ +G VIN+SS+ I V Y A+KG + MT+ LAL+ +P G+RVN Sbjct: 126 EAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNN 185 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEANFCTG 240 I PG I TP+ E A P+ RA + E M+ P+G +G+P E+ A A +LA SEA++ TG Sbjct: 186 IGPGAINTPINAEKFA-DPEQRADV-ESMI--PMGYIGEPEEIAAVAAWLASSEASYVTG 241 Query: 241 IELLVTGGAELGYGCKASR 259 I L GG L +A R Sbjct: 242 ITLFADGGMTLYPSFQAGR 260 >3AUT-A nrPDB Length = 269 Score = 144 bits (363), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 100/253 (39%), Positives = 146/253 (57%), Gaps = 15/253 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVIC---DKDESGGRALEQELPG--AVFI 59 T KVVV+TGG G+G + F A+VVI +++E+ E E G A+ + Sbjct: 11 TDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIV 70 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGT 118 DVT+E+DV LV I+ FG LD ++NNAG +P P E S + ++++ NL G Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSH--ELSLDNWNKVIDTNLTGA 128 Query: 119 YTLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + ++ A+ Y ++ +GNVIN+SS+ I V Y A+KG + MT+ LAL+ +P G Sbjct: 129 FLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKG 188 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEA 235 +RVN I PG + TP+ E A P RA + E M+ P+G +G+P EV A A FLA S+A Sbjct: 189 IRVNNIGPGAMNTPINAEKFA-DPVQRADV-ESMI--PMGYIGKPEEVAAVAAFLASSQA 244 Query: 236 NFCTGIELLVTGG 248 ++ TGI L GG Sbjct: 245 SYVTGITLFADGG 257 >4MOW-A nrPDB Length = 256 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 92/252 (36%), Positives = 140/252 (55%), Gaps = 15/252 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG-----RALEQELPGAVFI 59 ++ AGKV +VTG +GIGA I +A + GA VV+ G A+ + AV + Sbjct: 10 SKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAV 69 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGT 118 DV++ D + +V I +GRLD +VNN+G + P E + + +R+ + N+ G Sbjct: 70 GGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAP--IEAITEEHYRRQFDTNVFGV 127 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 T+ A+ +L + ++INISS+V +I + Y TKGAV A+T LAL+ P +R Sbjct: 128 LLTTQAAVKHLGEG-ASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIR 186 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EAN 236 VN I+PG I T + D A + L Q PLGR+G+P ++ + AVFLAS +A Sbjct: 187 VNAINPGMIVTEGTHSAGIIGSDLEAQV----LGQTPLGRLGEPNDIASVAVFLASDDAR 242 Query: 237 FCTGIELLVTGG 248 + TG L+V+GG Sbjct: 243 WMTGEHLVVSGG 254 >5ITV-A nrPDB Length = 255 Score = 133 bits (334), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 85/248 (34%), Positives = 137/248 (55%), Gaps = 13/248 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL--EQELPGAVFILCDVTQED 67 K V++TGG GIG V+AF+ A VV+ D DE+ G A+ ++ F+ D+T E Sbjct: 8 KTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEA 67 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHH-PPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + V + FG LD ++NNAG P E S + ++L++NL G + ++K AL Sbjct: 68 ACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELS--DWNKVLQVNLTGMFLMSKHAL 125 Query: 127 PY-LRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + L +GN+IN S+ G + Y A+KG V +TK++A+D + + +RVNC+ PG Sbjct: 126 KHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPG 185 Query: 186 NIWTPLWEELAALMPDPRATI----REGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240 I TPL E+ + + + T+ +E PL R+G+P E+ +FLAS+ +++ TG Sbjct: 186 IIDTPLNEK--SFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTG 243 Query: 241 IELLVTGG 248 + GG Sbjct: 244 SAITADGG 251 >1NFF-A nrPDB Length = 260 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 93/250 (37%), Positives = 130/250 (52%), Gaps = 15/250 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELPGAVFILCDVT 64 R GKV +V+GG RG+GA VRA V GA+VV D DE G + A ++ DVT Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVT 63 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT-LTK 123 Q K V + FG L +VNNAG E+ + ++++L++NL G + + Sbjct: 64 QPAQWKAAVDTAVTAFGGLHVLVNNAGI-LNIGTIEDYALTEWQRILDVNLTGVFLGIRA 122 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + P +G++INISS+ G G Y ATK AV +TK+ AL+ P G+RVN I Sbjct: 123 VVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIH 182 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIE 242 PG + TP M D + E + LGR +P EV V+LAS E+++ TG E Sbjct: 183 PGLVKTP--------MTD---WVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGAE 231 Query: 243 LLVTGGAELG 252 +V GG G Sbjct: 232 FVVDGGTVAG 241 >4NBT-A nrPDB Length = 240 Score = 123 bits (309), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 130/250 (52%), Gaps = 16/250 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 + GKV V+TGG +G+G I A+ GA+V+ D + L P + +VT Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD-----LTYSHPNVEGMYLNVTD 57 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 V+ I ++G++D +VNNAG + T AQ + ++++NL G + LT+L Sbjct: 58 VTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQ-WDAVIDVNLKGVFNLTRLV 116 Query: 126 LPYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG--VRVNCI 182 P ++ + G++INISS+VG G Y ATK V +T A + + G VRVN I Sbjct: 117 GPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAI 176 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 +PG I T + + + + D A + L R+GQP E+ A+FLAS +A++ TG Sbjct: 177 APGYIMTDILKTVPQDLLDKFAAL------TMLNRLGQPEEIAKVALFLASDDASYVTGQ 230 Query: 242 ELLVTGGAEL 251 + V GG L Sbjct: 231 TINVNGGMRL 240 >3RSH-A nrPDB Length = 251 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 87/246 (35%), Positives = 127/246 (51%), Gaps = 16/246 (6%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVTQED 67 GKV +VTG RGIG I GA+V+ ESG +A+ L + +VT + Sbjct: 12 GKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPE 71 Query: 68 DVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 ++ ++ FG +D +VNNAG R +E + + ++E NL + L+K Sbjct: 72 SIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKE---EEWSDIMETNLTSIFRLSKAV 128 Query: 126 LP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 L ++K QG +IN+ S+VG +G A Y A K V TK++A + + GV VN ++P Sbjct: 129 LRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAP 188 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIE 242 G I T + + L D + R LAQ P GR+G P E+ +A FLAS EA + TG Sbjct: 189 GFIETDMTKAL----NDEQ---RTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGET 241 Query: 243 LLVTGG 248 L V GG Sbjct: 242 LHVNGG 247 >4JRO-A nrPDB Length = 271 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 86/250 (34%), Positives = 130/250 (52%), Gaps = 20/250 (8%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVIC-----DKDESGGRALEQELPGAVFILCDV 63 GKV VVTGG RGIG I GA + + E + + + + +V Sbjct: 29 GKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAMKANV 88 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 +DV + I RFGR+D +VNNAG R +E + ++ +NL GT+ Sbjct: 89 AIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDE---WDDVININLKGTFLC 145 Query: 122 TK-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 TK ++ +++ G +IN++S+VG IG A YVA+K V +TK A + +P G+ VN Sbjct: 146 TKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGINVN 205 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASEAN-FC 238 ++PG I T + ++L D + +E MLAQ PLG G ++ A +FLAS+A+ + Sbjct: 206 AVAPGFITTDMTDKL-----DEKT--KEAMLAQIPLGAYGTTEDIANAVLFLASDASKYI 258 Query: 239 TGIELLVTGG 248 TG L V GG Sbjct: 259 TGQTLSVDGG 268 >4AVY-A nrPDB Length = 242 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 93/243 (38%), Positives = 122/243 (50%), Gaps = 14/243 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 YAG+ V+VTGG GIGA I F GA VV D G A P D+T Sbjct: 9 YAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRH--PRIRREELDITDS 66 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 ++ L RLD +VNNAG + EE F ++L LNL ++LA Sbjct: 67 QRLQRLFEA----LPRLDVLVNNAG---ISRDREEYDLATFERVLRLNLSAAMLASQLAR 119 Query: 127 PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186 P L + G+++NI+S+ G A Y A+KGA+ +T++LA + + +RVN I+PG Sbjct: 120 PLLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGW 179 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLV 245 I TPL A L D AT R M PL R G+ EV +AA FL A+F TG L V Sbjct: 180 IDTPLG---AGLKADVEAT-RRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAV 235 Query: 246 TGG 248 GG Sbjct: 236 DGG 238 >2HSD-A nrPDB Length = 253 Score = 120 bits (300), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 90/251 (35%), Positives = 137/251 (54%), Gaps = 16/251 (6%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV-FILCDVTQE 66 +GK V++TGG RG+GA R V +GARVV+ D + G A +EL A + DVT E Sbjct: 4 SGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIE 63 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 +D + +V+ FG +D +VNNAG E S + FR+++E+NL G + K + Sbjct: 64 EDWQRVVAYAREEFGSVDGLVNNAG-ISTGMFLETESVERFRKVVEINLTGVFIGMKTVI 122 Query: 127 PYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 P ++ + G+++NISS G +G A Y A+K V ++K A++ +RVN + PG Sbjct: 123 PAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPG 182 Query: 186 NIWTPLWEELAALMPDPRATIREG---MLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +TP+ E IR+G P+GR+G+P E+ A V L S+ +++ TG Sbjct: 183 MTYTPMTAETG---------IRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGA 233 Query: 242 ELLVTGGAELG 252 EL V GG G Sbjct: 234 ELAVDGGWTTG 244 >5T5Q-A nrPDB Length = 247 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 86/246 (34%), Positives = 127/246 (51%), Gaps = 13/246 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL--PGAV-FILCDV 63 + + +V+TG GIG I F SGA +V+ D D G A L P + I D Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 66 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + DD + V+ + RFG +D +V +AG + E + A R + +NL G + L K Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRT-ISINLDGVFYLCK 125 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 ALP L K +++ ++SL G Y ATKGA+ +MT+AL+ + +P RVN +S Sbjct: 126 RALPAL-KEDSSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAP-KTRVNGVS 183 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIE 242 PG I TP+ EL + + E M PL R+G+P+E+ + FL S A+F TG Sbjct: 184 PGIIETPMTSELL------KTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGET 237 Query: 243 LLVTGG 248 + V GG Sbjct: 238 IQVNGG 243 >1HXH-A nrPDB Length = 253 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 81/247 (32%), Positives = 134/247 (54%), Gaps = 14/247 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDV 63 R GKV +VTGG G+G +V+ + GA+V D +E+ G+ L EL ++F+ DV Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDV 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + E D +++ RR G L+ +VNNAG P E + F +LL++N + + Sbjct: 62 SSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDM-ETGRLEDFSRLLKINTESVFIGCQ 120 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD--ESPYGVRVNC 181 + ++++ G++IN++S+ + Q Y A+K AV+A+T+A AL + Y +RVN Sbjct: 121 QGIAAMKETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNS 180 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQP----LGRMGQPAEVGAAAVFLAS-EAN 236 I P I+TP+ + A+L P+ +E +L P GR P + +FLAS E++ Sbjct: 181 IHPDGIYTPMMQ--ASL---PKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDESS 235 Query: 237 FCTGIEL 243 +G EL Sbjct: 236 VMSGSEL 242 >6CI9-A nrPDB Length = 259 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 88/254 (34%), Positives = 127/254 (50%), Gaps = 14/254 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA----VFIL 60 T G+ +VTGG +GIG GI F N+G VVI +++ +L G + Sbjct: 5 TSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVR 64 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DVT +D + V+ET+ R G LD V NAG P R E+ + Q+L +N GT Sbjct: 65 ADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSG-RLEDLTPDDIEQVLGVNFKGTVY 123 Query: 121 LTKLALPYLRKS-QGNVINISSLVGAI-GQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + AL L S G V+ SS+ G I G Y A+K A + A++ +P + Sbjct: 124 IVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKIT 183 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANF 237 +N + PGNI T +E+ D A+ A P GR+G A++G AA+F A+ EA + Sbjct: 184 INAVLPGNIMTEGLDEMGQDYLDQMAS------AIPAGRLGSVADIGNAALFFATDEAAY 237 Query: 238 CTGIELLVTGGAEL 251 TG L+V GG L Sbjct: 238 VTGQTLVVDGGQVL 251 >1AE1-A nrPDB Length = 273 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 83/252 (32%), Positives = 125/252 (49%), Gaps = 18/252 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-------GRALEQELPGAVFILC 61 G +VTGG +GIG IV GARV C ++E R + G+V L Sbjct: 21 GTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLL 80 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAG---HHPPPQRPEETSAQGFRQLLELNLLGT 118 T+ D + V+ G+L+ +VNNAG H + ++ + + + ++ N Sbjct: 81 SRTERDKLMQTVAHVFD--GKLNILVNNAGVVIH----KEAKDFTEKDYNIIMGTNFEAA 134 Query: 119 YTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 Y L+++A P L+ SQ GNVI +SS+ G Y A+KGA+ MTK+LA + + + Sbjct: 135 YHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNI 194 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236 RVN ++PG I TPL E P + I ++ P+GR G+P EV A FL A+ Sbjct: 195 RVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAAS 254 Query: 237 FCTGIELLVTGG 248 + TG + GG Sbjct: 255 YITGQIIWADGG 266 >3FTP-A nrPDB Length = 270 Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 87/248 (35%), Positives = 126/248 (50%), Gaps = 19/248 (7%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG----GRALEQ---ELPGAVFILCD 62 +V +VTG RGIG I GA V+ E+G G A +Q E GAV + D Sbjct: 29 QVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLNVND 88 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 T D LV T++ FG L+ +VNNAG Q + +++ NL + L+ Sbjct: 89 ATAVD---ALVESTLKEFGALNVLVNNAGI-TQDQLAMRMKDDEWDAVIDTNLKAVFRLS 144 Query: 123 KLAL-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + L P ++ G ++NI+S+VG+ G V Y A K V MT+ALA + G+ VNC Sbjct: 145 RAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNC 204 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTG 240 ++PG I T + + L P + T + + PLGR+G P ++ A FLAS +A + TG Sbjct: 205 VAPGFIDTDMTKGL----PQEQQTALKTQI--PLGRLGSPEDIAHAVAFLASPQAGYITG 258 Query: 241 IELLVTGG 248 L V GG Sbjct: 259 TTLHVNGG 266 >3OSU-A nrPDB Length = 246 Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 82/249 (32%), Positives = 127/249 (51%), Gaps = 20/249 (8%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVIC-----DKDESGGRALEQELPGAVFILCDVT 64 K +VTG RGIG I G V + +K E+ ++ + + I +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 D+VK ++ E + +FG LD +VNNAG R +E Q + +++ NL G + Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKE---QEWDDVIDTNLKGVFNCI 121 Query: 123 KLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + A P LR+ G +IN+SS+VGA+G YVATK V +TK+ A + + G+ VN Sbjct: 122 QKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNA 181 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCT 239 ++PG I + + + L+ ++E ML Q PL R GQ ++ FLAS+ A + T Sbjct: 182 VAPGFIVSDMTDALS-------DELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYIT 234 Query: 240 GIELLVTGG 248 G + V GG Sbjct: 235 GQTIHVNGG 243 >1K2W-A nrPDB Length = 256 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 10/252 (3%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVT 64 R GK ++TG RGIG A+V GARV I D + RA E+ P A I DVT Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVT 61 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT-YTLTK 123 + + V+E + R+G +D +VNNA E T + + +L +N+ GT + + Sbjct: 62 DQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITR-ESYDRLFAINVSGTLFMMQA 120 Query: 124 LALPYLRKSQG-NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 +A + +G +IN++S G G+A Y ATK AV ++T++ L+ +G+ VN I Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAI 180 Query: 183 SPGNIWTPLWEELAALMPD----PRA-TIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236 +PG + W+ + A D PR R+ A P GRMG+ ++ A+FLA+ EA+ Sbjct: 181 APGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEAD 240 Query: 237 FCTGIELLVTGG 248 + V GG Sbjct: 241 YIVAQTYNVDGG 252 >5U9P-A nrPDB Length = 265 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 85/253 (33%), Positives = 126/253 (49%), Gaps = 19/253 (7%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG----RALEQELPGAVFILC 61 R G+ ++TG GRGIG + R +GA +VI D++E R E A + Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF 76 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSA---QGFRQLLELNLLGT 118 DV + V+ + E R G +D +VNNAG QR A + L+ +NL G Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAG----IQRRAPLDAFEPDDWHALMRVNLDGV 132 Query: 119 YTLTK-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + + + +A + + G +INI S+ + + PY ATKGAV +TK + D + YG+ Sbjct: 133 FNVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGI 192 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASEA- 235 + N ++PG T L AL+ D A + + + P GR GQ E+ AA+FLAS A Sbjct: 193 QANGLAPGYFETELNR---ALVDD--AAFSDWLCKRTPAGRWGQVDELCGAAIFLASAAS 247 Query: 236 NFCTGIELLVTGG 248 +F G L V GG Sbjct: 248 DFVNGQTLFVDGG 260 >4GKB-A nrPDB Length = 258 Score = 114 bits (286), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 73/203 (35%), Positives = 104/203 (51%), Gaps = 4/203 (1%) Query: 48 ALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGF 107 AL Q P A ++ ++ + + V++TI FGRLD +VNNAG + + F Sbjct: 49 ALAQRQPRATYLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGL--DAGRDAF 106 Query: 108 RQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA 167 LE NL+ Y + +P+L+ ++G ++NISS GQ Y A+KGA A+T+ Sbjct: 107 VASLERNLIHYYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTRE 166 Query: 168 LALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLG-RMGQPAEVGA 226 A+ +GVRVN + P + TPL+ A DP A + E PLG R P E+ Sbjct: 167 WAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIAD 226 Query: 227 AAVFLAS-EANFCTGIELLVTGG 248 AVFL S A+ TG L V GG Sbjct: 227 TAVFLLSPRASHTTGEWLFVDGG 249 >4E6P-A nrPDB Length = 259 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 83/252 (32%), Positives = 126/252 (50%), Gaps = 10/252 (3%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVT 64 R GK ++TG RGIG A+V GA V I D D R E+ P A + DVT Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDVT 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT-YTLTK 123 ++D + ++ T+ G LD +VNNA E T + + +L +N+ GT +TL Sbjct: 65 RQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITR-ESYEKLFAINVAGTLFTLQA 123 Query: 124 LALPYLRKSQG-NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 A + + +G +IN++S G G+A Y ATK AV ++T++ LD + + VN I Sbjct: 124 AARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAI 183 Query: 183 SPGNIWTPLWEELAALMP----DPRATIREGM-LAQPLGRMGQPAEVGAAAVFLAS-EAN 236 +PG + W+ + AL PR + + A P GRMG ++ A+FLAS E++ Sbjct: 184 APGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAESD 243 Query: 237 FCTGIELLVTGG 248 + V GG Sbjct: 244 YIVSQTYNVDGG 255 >1Q7C-A nrPDB Length = 244 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 127/250 (50%), Gaps = 20/250 (8%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVTQ 65 + GK+ +VTG RGIG I GA+V+ E+G +A+ L ++ +VT Sbjct: 3 FEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTD 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAG----HHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 +++++ + FG +D +VNNAG + + EE + ++E NL + L Sbjct: 63 PASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE-----WNDIIETNLSSVFRL 117 Query: 122 TKLAL-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 +K + ++K G +I I S+VG +G + A K + +K+LA + + G+ VN Sbjct: 118 SKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVN 177 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFC 238 ++PG I T + AL D RA G+LAQ P GR+G E+ A FLAS EA + Sbjct: 178 VVAPGFIETDMTR---ALSDDQRA----GILAQVPAGRLGGAQEIANAVAFLASDEAAYI 230 Query: 239 TGIELLVTGG 248 TG L V GG Sbjct: 231 TGETLHVNGG 240 >1AHH-A nrPDB Length = 255 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 82/250 (32%), Positives = 129/250 (51%), Gaps = 15/250 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE---QELPGAVFIL-C 61 R GK ++TG G GIG I F +GA VV+ D + + Q+L G F C Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 D+T E ++ L I + G++D +VNNAG P +P + FR+ ELN+ + L Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFHL 125 Query: 122 TKLALPYLRKSQGNVI-NISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 ++L P + K+ G VI I+S+ Y ++K A + + + +A D +RVN Sbjct: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFC 238 I+PG I T + + + P+ I + ML P+ R+GQP ++ AA+FL S A++ Sbjct: 186 GIAPGAILTDALKSV--ITPE----IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 Query: 239 TGIELLVTGG 248 +G L V+GG Sbjct: 240 SGQILTVSGG 249 >1YXM-A nrPDB Length = 303 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 83/256 (32%), Positives = 132/256 (51%), Gaps = 19/256 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELP-----GAVFI 59 G+V +VTGG GIG IV+ + G+ VVI + +S L+ LP + I Sbjct: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGT 118 C++ E++V LV T+ FG+++ +VNN G P E S++G+ +LE NL GT Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP--AEHISSKGWHAVLETNLTGT 135 Query: 119 YTLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + + K ++++ G+++NI A G AV A + V +TK+LAL+ + G+ Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EA 235 R+NC++PG I++ + + EG + P R+G P EV + FL S A Sbjct: 195 RINCVAPGVIYS---QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 Query: 236 NFCTGIELLVTGGAEL 251 +F TG + V GG L Sbjct: 252 SFITGQSVDVDGGRSL 267 >5CDY-A nrPDB Length = 244 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 124/248 (50%), Gaps = 16/248 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVTQ 65 + GK+ +VTG RGIG I V GA V+ E G A+ L ++ +V Sbjct: 3 FEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVD 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + T+++ FG +D +VNNAG R ++ Q +++ NL + L+K Sbjct: 63 PTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQ---DIIDTNLTSVFRLSK 119 Query: 124 LAL-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 + ++K G +I I S+VG +G A V Y A K V +K+LA + + G+ VN + Sbjct: 120 AVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVV 179 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTG 240 +PG I T + L D RA G+LAQ P R+G E+ +A FLAS EA++ +G Sbjct: 180 APGFIETDMTRTLT---DDQRA----GILAQVPANRLGDAKEIASAVAFLASDEASYISG 232 Query: 241 IELLVTGG 248 L V GG Sbjct: 233 ETLHVNGG 240 >2AE2-A nrPDB Length = 260 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 81/255 (31%), Positives = 131/255 (51%), Gaps = 9/255 (3%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-GRALEQELPGAVFI 59 MA G +VTGG RGIG GIV + GA V C +++ L Q + Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKV 60 Query: 60 ---LCDVTQEDDVKTLVSETIRRF-GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 +CD++ + + L++ F G+L+ +VNNAG + ++ + + + ++ +N Sbjct: 61 EASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGI-VIYKEAKDYTVEDYSLIMSINF 119 Query: 116 LGTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 Y L+ LA P+L+ S+ GNV+ ISS+ GA+ Y ATKGA+ +T+ LA + + Sbjct: 120 EAAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAK 179 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS- 233 +RVN + PG I T L E+ P+ + + + + L RMG+P E+ A FL Sbjct: 180 DNIRVNGVGPGVIATSL-VEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFP 238 Query: 234 EANFCTGIELLVTGG 248 A++ TG + V GG Sbjct: 239 AASYVTGQIIYVDGG 253 >4M8S-A nrPDB Length = 248 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 131/248 (52%), Gaps = 17/248 (6%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP--GAVFILCDVTQ 65 +GK+ +VTG RGIGA I +GA+V+ ESG A+ + L G + + + Sbjct: 7 SGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSAE 66 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + V+ L+++ + FG+LD +VNNAG R +E + + ++++NL + +K Sbjct: 67 PETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKE---EEWDDIMQVNLKSVFRASK 123 Query: 124 LALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 L + K + G +INI+S+VG +G A Y A K + +K++A + G+ VNC+ Sbjct: 124 AVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCV 183 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTG 240 +PG I T + L P T R+ AQ LGR G ++ A +FLAS +A + TG Sbjct: 184 APGFIDTDMTRAL------PEET-RQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITG 236 Query: 241 IELLVTGG 248 L V GG Sbjct: 237 QTLHVNGG 244 >4NBV-A nrPDB Length = 246 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 82/254 (32%), Positives = 128/254 (50%), Gaps = 17/254 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL----C 61 + G+V ++TG GIG + F GA VV+CD E+ R L + Sbjct: 2 KLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRV 61 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DVT+ D+V +V+ + R+D +VNNAG + + T AQ F ++++NL G + Sbjct: 62 DVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQ-FDAVIDVNLKGVFNC 120 Query: 122 TKLALPYLRKSQGN--VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + A+ L QG ++N SS+VG G Y A+K V TK A + P GVRV Sbjct: 121 AQ-AVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRV 179 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQP-LGRMGQPAEVGAAAVFLAS-EANF 237 N + PG + T E+ +PD + +GM + L R+ +PAE+ + FLAS +A++ Sbjct: 180 NAVCPGFVNT----EILQTVPDK---VLDGMTSSCWLRRLAEPAEIASIYAFLASDDASY 232 Query: 238 CTGIELLVTGGAEL 251 G+ + +GG L Sbjct: 233 VNGVAIEASGGMSL 246 >4CQM-B nrPDB Length = 244 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 127/250 (50%), Gaps = 25/250 (10%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL-CDVTQEDD 68 KV V GG RGIG + + G R+ + ++ G +A +L G CDV +E D Sbjct: 10 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 69 Query: 69 VKTLVSETIRRFGRLDCVVNNAGHHPP----PQRPEETSAQGFRQLLELNLLGTYTLTKL 124 V+ E + GR++ +VN AG + + E+ +Q L NLLG+ K Sbjct: 70 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ-----LHTNLLGSMLTCKA 124 Query: 125 ALPYLRKSQG-NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 A+ + + QG +++N+ S+VG G + Y A+KG + ++ALA + + +RVN ++ Sbjct: 125 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 184 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ--PLGRMGQPAEVGAAAVFLASEANFCTGI 241 PG + T + ++L +E L + PLGR G+ EV A VFL E+ + TG Sbjct: 185 PGFVHTDMTKDL-----------KEEHLKKNIPLGRFGETIEVAHAVVFLL-ESPYITGH 232 Query: 242 ELLVTGGAEL 251 L+V GG +L Sbjct: 233 VLVVDGGLQL 242 >3UN1-A nrPDB Length = 260 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 87/252 (34%), Positives = 135/252 (53%), Gaps = 23/252 (9%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVT 64 R KVVV+TG +GIGAG+VRA+ + RVV R+++ P + D++ Sbjct: 25 RNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATS------RSIKPSADPDIHTVAGDIS 78 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-K 123 + + +V E I RFGR+D +VNNAG E T + + L +N+ G + +T + Sbjct: 79 KPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQ-EDYDHNLGVNVAGFFHITQR 137 Query: 124 LALPYLRKSQGNVINIS-SLVGA--IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 A L++ G++++I+ SLV +G A+ + TKG + A+T++LA++ S GVRVN Sbjct: 138 AAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASL-TKGGLNAVTRSLAMEFSRSGVRVN 196 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG 240 +SPG I TP+ P + G+ P+GRMG+ +V A ++L A F TG Sbjct: 197 AVSPGVIKTPMH-------PAETHSTLAGL--HPVGRMGEIRDVVDAVLYL-EHAGFITG 246 Query: 241 IELLVTGGAELG 252 L V GG G Sbjct: 247 EILHVDGGQNAG 258 >1X1T-A nrPDB Length = 260 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 91/258 (35%), Positives = 131/258 (50%), Gaps = 23/258 (8%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI--------CDKDESGGRALEQELPGAVFIL 60 GKV VVTG GIG GI A GA +V+ +K +G A Q ++ Sbjct: 4 GKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAA--QHGVKVLYDG 61 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTY 119 D+++ + V+ LV +R+ GR+D +VNNAG H E+ + + +L LNL + Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTA--LIEDFPTEKWDAILALNLSAVF 119 Query: 120 TLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 T ALP+++K G +INI+S G + A YVA K V TK AL+ + G+ Sbjct: 120 HGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGIT 179 Query: 179 VNCISPGNIWTPLWE-ELAALMP----DPRATIREGMLA--QPLGRMGQPAEVGAAAVFL 231 N I PG + TPL E +++AL D RE +L+ QP + P ++G AVFL Sbjct: 180 ANAICPGWVRTPLVEKQISALAEKNGVDQETAARE-LLSEKQPSLQFVTPEQLGGTAVFL 238 Query: 232 ASEANF-CTGIELLVTGG 248 AS+A TG + V GG Sbjct: 239 ASDAAAQITGTTVSVDGG 256 >2NM0-A nrPDB Length = 253 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 82/250 (32%), Positives = 128/250 (51%), Gaps = 18/250 (7%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-GAVFILCDVTQ 65 + + V+VTGG RGIG I RAF ++G +V I + SG E P G + + CD+T Sbjct: 19 HMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYR--SG------EPPEGFLAVKCDITD 70 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + V+ E G ++ ++ NAG Q S + F ++E NL GT+ + K A Sbjct: 71 TEQVEQAYKEIEETHGPVEVLIANAGV-TKDQLLMRMSEEDFTSVVETNLTGTFRVVKRA 129 Query: 126 -LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 LR +G V+ ISS+VG +G A Y A+K + ++LA + + N ++P Sbjct: 130 NRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAP 189 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIEL 243 G + T + + L + RA I + PLGR +P E+ A FLAS +A++ TG + Sbjct: 190 GFVDTDMTK---VLTDEQRANIVSQV---PLGRYARPEEIAATVRFLASDDASYITGAVI 243 Query: 244 LVTGGAELGY 253 V GG +G+ Sbjct: 244 PVDGGLGMGH 253 >2HQ1-A nrPDB Length = 247 Score = 108 bits (269), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 81/251 (32%), Positives = 124/251 (49%), Gaps = 16/251 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG-RALEQELPGA----VFIL 60 + GK +VTG RG+G I N GA +V+ S A +E A V Sbjct: 2 QLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAK 61 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DV +DV+ +V + FGR+D +VNNAG + S + + +L NL Y Sbjct: 62 GDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLK-MSEKDWDDVLNTNLKSAYL 120 Query: 121 LTK-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 TK ++ L++ G +INI+S+ G IG A Y A+K + TK++A + + G+ Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYC 180 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANF 237 N ++PG I T ++ ++PD ++E L PL R G P EV FLAS ++N+ Sbjct: 181 NAVAPGIIKT----DMTDVLPDK---VKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 238 CTGIELLVTGG 248 TG + + GG Sbjct: 234 ITGQVINIDGG 244 >4DBZ-A nrPDB Length = 281 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 84/254 (33%), Positives = 120/254 (47%), Gaps = 24/254 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF----ILCDVTQ 65 +V +VTG GIG I R G RV +C + E G R +EL A CDV Sbjct: 27 EVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRS 86 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 +++ LV+ + R+G +D +VNNAG P E + + + ++E NL G + +TK Sbjct: 87 VPEIEALVAAVVERYGPVDVLVNNAGR-PGGGATAELADELWLDVVETNLTGVFRVTKQV 145 Query: 126 LP---YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 L L + G ++NI+S G G A PY A+K V TKAL L+ + G+ VN + Sbjct: 146 LKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAV 205 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQ-----PLGRMGQPAEV----------GAA 227 PG + TP+ + D E + P+GR QP+EV GAA Sbjct: 206 CPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPGAA 265 Query: 228 AVFLASEANFCTGI 241 AV A N C G+ Sbjct: 266 AV-TAQALNVCGGL 278 >5OJG-A nrPDB Length = 260 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 75/252 (29%), Positives = 128/252 (50%), Gaps = 8/252 (3%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-GRALE----QELPGAVFIL 60 R+ GKV +VT +GIG I ++ GA VVI +++ A+E + L I Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 + DD K LV T+++FG+++ +VNN G +P E S Q + +L E+N+ + Sbjct: 67 GHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQ 126 Query: 121 LTKLALPYLRKSQGNVINISSLVGAIGQAQAV-PYVATKGAVTAMTKALALDESPYGVRV 179 +TKL P++ K G I ++ A + Y TK + +T+ALA+ + +RV Sbjct: 127 MTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRV 186 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N I+PG I T + + L D + + + LGR+G P + +LAS ++++ Sbjct: 187 NGIAPGVIKTKMSQVLWDGGEDAEKELTD-IQEIALGRLGVPDDCAGTVAYLASDDSSYI 245 Query: 239 TGIELLVTGGAE 250 TG +++ GG + Sbjct: 246 TGEMIIIAGGVQ 257 >2AG5-A nrPDB Length = 246 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 82/252 (32%), Positives = 125/252 (49%), Gaps = 13/252 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R GKV+++T +GIG AF GA+V+ D +ES + LE+ PG + DVT+ Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK-YPGIQTRVLDVTK 61 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + + +E RLD + N AG HH EE + + + LN+ Y + K Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEE---KDWDFSMNLNVRSMYLMIK 114 Query: 124 LALP-YLRKSQGNVINISSLVGAI-GQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 LP L + GN+IN+SS+ ++ G Y TK AV +TK++A D G+R NC Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTG 240 + PG + TP +E +P + + Q GR E+ V+LAS E+ + TG Sbjct: 175 VCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTG 234 Query: 241 IELLVTGGAELG 252 +++ GG LG Sbjct: 235 NPVIIDGGWSLG 246 >3F9I-A nrPDB Length = 249 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 16/244 (6%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-LCDVTQED 67 GK ++TG GIG+ I R G++V+I +E ++L L I +C++ ++ Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLANKE 73 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALP 127 + L+S+T LD +V NAG Q F +++++NL + L + A+ Sbjct: 74 ECSNLISKT----SNLDILVCNAGI-TSDTLAIRMKDQDFDKVIDINLKANFILNREAIK 128 Query: 128 -YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186 ++K G +INISS+VG G Y A+K + MTK+L+ + + G+ VN ++PG Sbjct: 129 KMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGF 188 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELL 244 I + + ++L RE ++ + PLG G P +V A FLAS A++ TG L Sbjct: 189 IKSDMTDKL-------NEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTLH 241 Query: 245 VTGG 248 V GG Sbjct: 242 VNGG 245 >4FC7-A nrPDB Length = 277 Score = 107 bits (266), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 79/252 (31%), Positives = 128/252 (50%), Gaps = 13/252 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC-----DVT 64 KV +TGGG GIG I F+ G VI + ++L GA C DV Sbjct: 28 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 87 Query: 65 QEDDVKTLVSETIRRFGRLDCVVN-NAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 V V + ++ FGR+D ++N AG+ P S F+ +++++ GT+ +++ Sbjct: 88 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPA--GALSFNAFKTVMDIDTSGTFNVSR 145 Query: 124 -LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 L + R G ++NI++ +G GQA V + K AV AMT+ LA++ P +RVN + Sbjct: 146 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 205 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I E + P+A++ + A PL R+G E+ + ++LAS A++ TG Sbjct: 206 APGPISG---TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 262 Query: 242 ELLVTGGAELGY 253 L+ GGA L + Sbjct: 263 VLVADGGAWLTF 274 >2EW8-A nrPDB Length = 249 Score = 106 bits (265), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 84/251 (33%), Positives = 128/251 (50%), Gaps = 17/251 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-----KDESGGRALEQELPGAVFIL 60 R K+ V+TGG GIG I F GA + I D + E+ R L + + + + Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRV---LTVK 60 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 CDV+Q DV+ + I FGR D +VNNAG +P E T Q +++ E+N+ + Sbjct: 61 CDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQ-WKKTFEINVDSGFL 119 Query: 121 LTKLALPYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + K +P ++++ G +IN++S + Y++TK A T+ALA D G+ V Sbjct: 120 MAKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITV 179 Query: 180 NCISPGNIWTPLWEELA-ALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANF 237 N I+P + T E A + M D + ML Q + R+ P ++ AA FLAS +A+F Sbjct: 180 NAIAPSLVRTATTEASALSAMFD----VLPNML-QAIPRLQVPLDLTGAAAFLASDDASF 234 Query: 238 CTGIELLVTGG 248 TG L V GG Sbjct: 235 ITGQTLAVDGG 245 >2PNF-A nrPDB Length = 248 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 126/250 (50%), Gaps = 14/250 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-----AVFIL 60 + GKV +VTG RGIG I ++G+ V+I +A+ +E+ A + Sbjct: 4 KLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVE 63 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 ++ E+ + E +D +VNNAG + S + ++L++NL GT+ Sbjct: 64 MNLLSEESINKAFEEIYNLVDGIDILVNNAGI-TRDKLFLRMSLLDWEEVLKVNLTGTFL 122 Query: 121 LTKLAL-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 +T+ +L +++ G ++NISS+VG G V Y TK + TK+LA + +P V V Sbjct: 123 VTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238 N ++PG I T + A L + + +E + PLGR G P EV +FL SE A++ Sbjct: 183 NAVAPGFIETDM---TAVLSEEIKQKYKEQI---PLGRFGSPEEVANVVLFLCSELASYI 236 Query: 239 TGIELLVTGG 248 TG + V GG Sbjct: 237 TGEVIHVNGG 246 >1GEG-A nrPDB Length = 256 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 81/253 (32%), Positives = 124/253 (49%), Gaps = 17/253 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP----GAVFILCDVTQ 65 KV +VTG G+GIG I V G V I D +++ +A+ E+ AV + DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRP-EETSAQGFRQLLELNLLGTYTLTKL 124 D V V + + G D +VNNAG P P E + + ++ +N+ G + Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAG--VAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 125 ALPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 A+ +K G +IN S G +G + Y ++K AV +T+ A D +P G+ VN Sbjct: 121 AVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 183 SPGNIWTPLWEEL------AALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EA 235 PG + TP+W E+ AA P T E LGR+ +P +V A +LAS ++ Sbjct: 181 CPGIVKTPMWAEIDRQVSEAAGKPLGYGT-AEFAKRITLGRLSEPEDVAACVSYLASPDS 239 Query: 236 NFCTGIELLVTGG 248 ++ TG LL+ GG Sbjct: 240 DYMTGQSLLIDGG 252 >4DMM-A nrPDB Length = 269 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 82/250 (32%), Positives = 124/250 (49%), Gaps = 24/250 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL-----CDVT 64 ++ +VTG RGIG I +GA+V + +G A DV+ Sbjct: 29 RIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKADVS 88 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 QE +V+ L + I R+GRLD +VNNAG R + ++ +L+LNL G + + Sbjct: 89 QESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDD---WQSVLDLNLGGVFLCS 145 Query: 123 KLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + A L++ G +INI+S+VG +G Y A K V +TK +A + + G+ VN Sbjct: 146 RAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNA 205 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGML-AQPLGRMGQPAEVGAAAVFLASE--ANFC 238 ++PG I T + ELAA E +L PLGR G+ AEV FLA++ A + Sbjct: 206 VAPGFIATDMTSELAA----------EKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYI 255 Query: 239 TGIELLVTGG 248 TG + + GG Sbjct: 256 TGQVINIDGG 265 >5JY1-A nrPDB Length = 274 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 87/255 (34%), Positives = 130/255 (50%), Gaps = 12/255 (4%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG----AVFILCDVTQ 65 +V +VTG G GIG G+ R+F N GA V+I + +ES GR +EQE+ ++F+ DVT Sbjct: 15 RVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTDVTS 74 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + ++ V + +FG LD +VNNA P EE + + Q L +L T+ + A Sbjct: 75 KASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAMRAA 134 Query: 126 L-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 P + G ++N S+ G Y K + +T++ A + + + VN I+P Sbjct: 135 FVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNAIAP 194 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAE-VGAAAVFLASE-ANFCTGIE 242 + + ELAA P+ A+PLGR G P + +G AAVF ASE + F TG Sbjct: 195 TAMGATFF-ELAAKNPE---FAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVTGET 250 Query: 243 LLVTGGAEL-GYGCK 256 L V GG L GY + Sbjct: 251 LHVDGGLHLPGYNSR 265 >2O23-A nrPDB Length = 265 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 74/228 (32%), Positives = 114/228 (50%), Gaps = 18/228 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVTQED 67 G V V+TGG G+G V GA V+ D SGG A ++L VF DVT E Sbjct: 12 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEK 71 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQ-----RPEETSAQGFRQLLELNLLGTYTLT 122 DV+T ++ +FGR+D VN AG + + + + + F+++L++NL+GT+ + Sbjct: 72 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVI 131 Query: 123 KLALPYLRKSQ-------GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 +L + +++ G +IN +S+ GQ Y A+KG + MT +A D +P Sbjct: 132 RLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI 191 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAE 223 G+RV I+PG TPL L P+ + P R+G PAE Sbjct: 192 GIRVMTIAPGLFGTPLLTSL----PEKVCNFLASQVPFP-SRLGDPAE 234 >3EMK-A nrPDB Length = 246 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 80/243 (32%), Positives = 120/243 (49%), Gaps = 10/243 (4%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL-CDVTQED 67 G+ +VTG G+G I RA GA V + E + L EL +F+ +++ + Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDRE 66 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK-LAL 126 VK L + G +D +VNNAG S + + +L +NL + LT+ L Sbjct: 67 AVKALGQKAEEEMGGVDILVNNAGITRDGLFVR-MSDEDWDAVLTVNLTSVFNLTRELTH 125 Query: 127 PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186 P +R+ G +INI+S+VG G Y A+K + +K+LA + + V VNCI+PG Sbjct: 126 PMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAPGF 185 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLV 245 I + + +L D M P+ RMG A++ AA V+LAS EA + TG L V Sbjct: 186 IESAMTGKLNEKQKDAI------MGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTLHV 239 Query: 246 TGG 248 GG Sbjct: 240 NGG 242 >5IZ4-A nrPDB Length = 271 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 82/267 (30%), Positives = 132/267 (49%), Gaps = 26/267 (9%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG------RALEQELPGAVF 58 T+ + V V+TG GIGA F +G V I + D+S AL ++ Sbjct: 10 TQSSTPVCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTL 69 Query: 59 IL-CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHP--PPQRPEETSAQGFRQLLELNL 115 I DV ++ D + V R+ R+D ++N AG P ++ F ++ +NL Sbjct: 70 IFDADVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNL 129 Query: 116 LGTYTLTKLALPYLRKSQG-----NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALAL 170 +G Y +T+ A+P LR+S +V+N+SSL G G ++ Y A+KGAV +T +LA Sbjct: 130 IGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLAR 189 Query: 171 DESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-----PLGRMGQPAEVG 225 + +P+ +RVN ++PG + L L+ A +G+L++ PL R+ +PAE+ Sbjct: 190 NLAPH-IRVNALAPGMVDDGL------LLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIA 242 Query: 226 AAAVFLASEANFCTGIELLVTGGAELG 252 A FL + A TG + G LG Sbjct: 243 ELAWFLTAHAPAITGQVIAAENGLLLG 269 >2BGM-A nrPDB Length = 278 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 69/231 (29%), Positives = 118/231 (51%), Gaps = 12/231 (5%) Query: 27 RAFVNSGARVVICDKDESGGRALEQEL--PGAV-FILCDVTQEDDVKTLVSETIRRFGRL 83 + FV GA+VVI D + G+ + + P + F+ CDVT+++DV+ LV TI + G+L Sbjct: 34 KLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGKL 93 Query: 84 DCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA----LPYLRKSQGNVIN 138 D + N G P E + F++++++N+ G + + K A +P + S + Sbjct: 94 DIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTAS 153 Query: 139 ISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAAL 198 ISS G + Y ATK AV +T +L + YG+RVNC+SP + +PL ++ + Sbjct: 154 ISSFTAGEGVSHV--YTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGV 211 Query: 199 MPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEANFCTGIELLVTGG 248 R A G + + +V A +LA E+ + +G+ L++ GG Sbjct: 212 -DSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGG 261 >1E3W-A nrPDB Length = 261 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 128/258 (49%), Gaps = 28/258 (10%) Query: 1 MATGTR-YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVF 58 MA R G V V+TGG G+G + V GA V+ D S G ++L G +F Sbjct: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-------HHPPPQRPEETSAQGFRQLL 111 +VT E +V+ ++ +FGR+D VN AG +H ++ + + + F++++ Sbjct: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHE--KKNQVHTLEDFQRVI 118 Query: 112 ELNLLGTYTLTKLALPYLRKSQ-------GNVINISSLVGAIGQAQAVPYVATKGAVTAM 164 +NL+GT+ + +L + +++ G +IN +S+ GQ Y A+KG + M Sbjct: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 Query: 165 TKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PL-GRMGQPA 222 T +A D +P G+RV I+PG TPL L PD T+R + +Q P R+G PA Sbjct: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTL----PD---TVRNFLASQVPFPSRLGDPA 231 Query: 223 EVGAAAVFLASEANFCTG 240 E A V + E F G Sbjct: 232 EY-AHLVQMVIENPFLNG 248 >2CDH-G nrPDB Length = 244 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 76/246 (30%), Positives = 119/246 (48%), Gaps = 15/246 (6%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVI-----CDKDESGGRALEQELPGAVFILCDVTQ 65 VVVVTG RGIG I + +G +V++ E + +E A+ DV++ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 E DV+ ++ I +G +D VVNNAG +Q + ++++LNL G + T+ A Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQ-WDEVIDLNLTGVFLCTQAA 121 Query: 126 LP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 ++K +G +INI+S+VG IG Y A K V +K A + + + VN + P Sbjct: 122 TKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCP 181 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE--ANFCTGIE 242 G I + + +L M ++ + PLGR GQP V FLA A++ TG Sbjct: 182 GFIASDMTAKLGEDME------KKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQA 235 Query: 243 LLVTGG 248 + GG Sbjct: 236 FTIDGG 241 >4BO1-A nrPDB Length = 269 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 85/248 (34%), Positives = 121/248 (48%), Gaps = 17/248 (6%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-----GAVFILCDV 63 GKV +VTG RGIG I GA V+ SG + + L GA +L DV Sbjct: 27 GKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL-DV 85 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + ++ V + + G+ VVNNAG + F ++ NL Y L+K Sbjct: 86 SSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWF-DVVNTNLNSLYRLSK 144 Query: 124 LALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 L + K++ G +INI S+VGA+G A Y A K + T+ALA + + VN + Sbjct: 145 AVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAV 204 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTG 240 +PG I T + EL P+ + RE +L Q PLGR+GQ E+ FLAS+ A + TG Sbjct: 205 APGFIDTDMTREL----PEAQ---REALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTG 257 Query: 241 IELLVTGG 248 + V GG Sbjct: 258 ATVPVNGG 265 >4RZI-B nrPDB Length = 240 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 81/241 (33%), Positives = 117/241 (48%), Gaps = 16/241 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 KV+VVTGG RGIGA IV+ GA+V D GG A+ ++ +VT + + Sbjct: 9 KVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT------EALGVVANVTDLESM 62 Query: 70 KTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT-YTLTKLALPY 128 +E + G + VV NAG P+ T A + +L +NL G Y++ Sbjct: 63 TAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPAD-WDAVLNVNLKGVAYSIKPFIEGM 121 Query: 129 LRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIW 188 + G+++ ISS+ G G Y ATK V M K+LA + + YGVR N ++PG I Sbjct: 122 YERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFID 181 Query: 189 TPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS--EANFCTGIELLVT 246 T E A+ D R I + + P R G+P E+ A FL S +++ TG L V Sbjct: 182 T---EMTLAIREDIREKITKEI---PFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVN 235 Query: 247 G 247 G Sbjct: 236 G 236 >2UVD-A nrPDB Length = 246 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 120/250 (48%), Gaps = 20/250 (8%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK-DESGGRALEQELP----GAVFILCDV 63 GKV +VTG RGIG I GA VV+ +E + E+ A+ + DV Sbjct: 4 GKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRADV 63 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPP--QRPEETSAQGFRQLLELNLLGTYTL 121 +DV +V +T+ FG++D +VNNAG R +E + + ++ NL G + Sbjct: 64 ANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKE---EEWDTVINTNLKGVFLC 120 Query: 122 TKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 TK ++ R+ G ++NI+S+VG G YVA K V +TK A + + + VN Sbjct: 121 TKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVN 180 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFC 238 I+PG I T + + L I+ ML P + G+ ++ A F AS+ + + Sbjct: 181 AIAPGFIATDMTDVL-------DENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYI 233 Query: 239 TGIELLVTGG 248 TG L V GG Sbjct: 234 TGQTLNVDGG 243 >3GRP-A nrPDB Length = 266 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 122/249 (48%), Gaps = 16/249 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL-CDVT 64 + G+ +VTG GIG I R F GA V + E + + +L VF+ +++ Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLS 83 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 +K L R +D +VNNAG R ++ Q + +L +NL TLT Sbjct: 84 DRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQD---QDWDDVLAVNLTAASTLT 140 Query: 123 K-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + L +R+ G +INI+S+VG +G Y A K + +KALA + + + VNC Sbjct: 141 RELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNC 200 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCT 239 I+PG I + + ++L +E ++A P+ RMG E+ A V+LAS EA + T Sbjct: 201 IAPGFIKSAMTDKL-------NEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLT 253 Query: 240 GIELLVTGG 248 G L + GG Sbjct: 254 GQTLHINGG 262 >4RZH-A nrPDB Length = 247 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 80/252 (31%), Positives = 125/252 (49%), Gaps = 18/252 (7%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVI-CDKDESGGRALEQELPG----AVFI 59 T +V +VTG RGIG A +G +VV+ + + A+ E+ A+ + Sbjct: 2 TALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAV 61 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 +V D+V L+ T+ +F R+D +VNNAG + ++ +++LNL G + Sbjct: 62 QANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLL-RMKLEDWQAVIDLNLTGVF 120 Query: 120 TLTK-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 TK ++ L++ G +INI+S+ G +G Y A K V TK +A + + GV Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVT 180 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE--AN 236 VN ++PG I T + E L A +P I + + PL R GQP EV FLA++ A Sbjct: 181 VNAVAPGFIATDMTENLNA---EP---ILQFI---PLARYGQPEEVAGTIRFLATDPAAA 231 Query: 237 FCTGIELLVTGG 248 + TG V GG Sbjct: 232 YITGQTFNVDGG 243 >4IIN-A nrPDB Length = 271 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 126/254 (49%), Gaps = 14/254 (5%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-GRALEQELP----GA 56 + ++ GK V++TG +GIGA I + + G +V I + + AL+ EL A Sbjct: 22 SNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKA 81 Query: 57 VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 I D E D + ++ G L +VNNAG + + + F +++ NL Sbjct: 82 AVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGV-VRDKLAIKMKTEDFHHVIDNNLT 140 Query: 117 GTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 + + AL + KS+ G+V+N++S++G G Y A+KG + AM+K+ A + + Sbjct: 141 SAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALR 200 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 +R N ++PG I T + A L + +A + + PL R+G EV A FL S+ Sbjct: 201 NIRFNSVTPGFIETDMN---ANLKDELKADYVKNI---PLNRLGSAKEVAEAVAFLLSDH 254 Query: 235 ANFCTGIELLVTGG 248 +++ TG L V GG Sbjct: 255 SSYITGETLKVNGG 268 >3W8F-A nrPDB Length = 260 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 85/256 (33%), Positives = 121/256 (47%), Gaps = 19/256 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVIC-----DKDESGGRALEQEL-PGAVFILCD 62 GK VVTG GIG + +GA VVI + E LE + A ++ D Sbjct: 4 GKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNAD 63 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 ++ + +++ G LD +VNNAG H P EE + ++ LNL + Sbjct: 64 LSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAP--IEEFPVDKWNAIIALNLSAVFHG 121 Query: 122 TKLALPYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 T ALP ++K G +INI+S G + YVA K V +TK AL+ + G+ N Sbjct: 122 TAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCN 181 Query: 181 CISPGNIWTPLWEELAALMP-----DPRATIREGMLA--QPLGRMGQPAEVGAAAVFLAS 233 I PG + TPL E+ + D A RE +LA QP + P ++G AAVFL+S Sbjct: 182 AICPGWVRTPLVEKQIEAISQQKGIDIEAAARE-LLAEKQPSLQFVTPEQLGGAAVFLSS 240 Query: 234 -EANFCTGIELLVTGG 248 A+ TG L + GG Sbjct: 241 AAADQMTGTTLSLDGG 256 >2B4Q-A nrPDB Length = 276 Score = 96.7 bits (239), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 80/255 (31%), Positives = 125/255 (49%), Gaps = 17/255 (6%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG---AVFILCDVT 64 AG++ +VTGG RGIG I + + +GARV IC +D L I D++ Sbjct: 28 AGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLS 87 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 E + L RLD +VNNAG E G+ ++++LN+ ++ + Sbjct: 88 SEAGARRLAQALGELSARLDILVNNAGTSWGAAL-ESYPVSGWEKVMQLNVTSVFSCIQQ 146 Query: 125 ALPYLRKSQ-----GNVINISSLVG--AIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 LP LR+S VINI S+ G A+G+ QA Y +K A+ +++ LA + + Sbjct: 147 LLPLLRRSASAENPARVINIGSVAGISAMGE-QAYAYGPSKAALHQLSRMLAKELVGEHI 205 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEAN- 236 VN I+PG + + +A DP+A + + P+GR G+P E+ A A+ LA A Sbjct: 206 NVNVIAPGRFPSRMTRHIA---NDPQA-LEADSASIPMGRWGRPEEMAALAISLAGTAGA 261 Query: 237 FCTGIELLVTGGAEL 251 + TG + + GG L Sbjct: 262 YMTGNVIPIDGGFHL 276 >3WOH-A nrPDB Length = 251 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/253 (29%), Positives = 117/253 (46%), Gaps = 20/253 (7%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELP----GAVFILCD 62 +GKV +VTGG RG+G + GA V I D+S + + E+ A CD Sbjct: 10 SGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRCD 69 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V+ + V V G +D +VNNAG + + ++ NL G + Sbjct: 70 VSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGL-AASIKDEDYDAVMNTNLKGAFLFI 128 Query: 123 KLA-LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 K ++RK G++INISS+ G G A Y + K + +TK++A + + VR N Sbjct: 129 KACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNA 188 Query: 182 ISPGNIWTPLWEELA--ALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEANFC 238 ++PG I T + ++L + DP P+ R G+P EV FLA E+++ Sbjct: 189 VAPGLIATDMTQDLVDDSKRLDP----------VPMRRFGRPDEVAGLVAFLAGDESSYI 238 Query: 239 TGIELLVTGGAEL 251 TG + V GG + Sbjct: 239 TGQVVCVDGGMAM 251 >1BDB-A nrPDB Length = 277 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 76/242 (31%), Positives = 114/242 (47%), Gaps = 14/242 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF-ILCDVT 64 + G+ V++TGG G+G +V FV GA+V + DK LE + V I+ DV Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVR 61 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAG----HHPPPQRPEETSAQGFRQLLELNLLGTYT 120 +D K S + RFG++D ++ NAG PEE+ F ++ +N+ G Sbjct: 62 SLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIH 121 Query: 121 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 K LP L S+GNVI S G Y A K A+ + + LA + +PY VRVN Sbjct: 122 AVKACLPALVASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-VRVN 180 Query: 181 CISPGNIWTPLWEELA------ALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 + G I + L + A+ P A + + +L P+GRM + E A VF A+ Sbjct: 181 GVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVL--PIGRMPEVEEYTGAYVFFATR 238 Query: 235 AN 236 + Sbjct: 239 GD 240 >2CFC-A nrPDB Length = 250 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 121/250 (48%), Gaps = 19/250 (7%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVF-ILCDVT 64 +V +VTG G G I F+ G RV D E R V + DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 E DV ++ T+ +FG +D +VNNAG + T + F +++ +N+ G + Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 123 KLALPY-LRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + LP+ L + G ++NI+S+ + Y +KGAV +TK++A+D + G+R N Sbjct: 123 RAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNA 182 Query: 182 ISPGNIWTPL--WEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANF 237 + PG I TP+ W + P +R+ +LA+ P +G A+V A +FLA E A + Sbjct: 183 VCPGMIETPMTQWR-----LDQPE--LRDQVLARIPQKEIGTAAQVADAVMFLAGEDATY 235 Query: 238 CTGIELLVTG 247 G L++ G Sbjct: 236 VNGAALVMDG 245 >2GDZ-A nrPDB Length = 267 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 65/199 (32%), Positives = 100/199 (50%), Gaps = 21/199 (10%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG----RALEQELP--GAVFILCD 62 GKV +VTG +GIG A + GA+V + D + G AL ++ +FI CD Sbjct: 7 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCD 66 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V + ++ + + FGRLD +VNNAG + + + + L++NL+ + T Sbjct: 67 VADQQQLRDTFRKVVDHFGRLDILVNNAG---------VNNEKNWEKTLQINLVSVISGT 117 Query: 123 KLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTK--ALALDESPYG 176 L L Y+ K G +IN+SSL G + AQ Y A+K + T+ ALA + G Sbjct: 118 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 177 Query: 177 VRVNCISPGNIWTPLWEEL 195 VR+N I PG + T + E + Sbjct: 178 VRLNAICPGFVNTAILESI 196 >3PPI-A nrPDB Length = 281 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 81/252 (32%), Positives = 111/252 (44%), Gaps = 35/252 (13%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFI 59 M T ++ G +V+GG G+G VR G VVI D G+AL EL A F+ Sbjct: 22 MVTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFV 81 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQ-----GFRQLLELN 114 +VT ED V + E + GRL V G QR + GF + ++L Sbjct: 82 STNVTSEDSVLAAI-EAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLY 140 Query: 115 LLGTYTLTKL-------ALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA 167 L GTY + +L A P +G ++ +S+ G GQ Y A K V +T A Sbjct: 141 LNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIA 200 Query: 168 LALDESPYGVRVNCISPGNIWTPLWE--------ELAALMPDPRATIREGMLAQPLGRMG 219 A D S G+RVN I+PG + TP+ E + AA +P P+ R+G Sbjct: 201 AARDLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPK-------------RLG 247 Query: 220 QPAEVGAAAVFL 231 P E AA FL Sbjct: 248 TPDEFADAAAFL 259 >5VT6-A nrPDB Length = 269 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 72/256 (28%), Positives = 121/256 (47%), Gaps = 15/256 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD---KDESGGRALEQELPGAVF-- 58 G+ A +V VTGG G+GA I R ++G V + D + + G F Sbjct: 20 GSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKA 79 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 DV + + + + FG++D ++NNAG + T + ++ +L Sbjct: 80 YAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGD-WDAVMRTDLDAM 138 Query: 119 YTLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + +TK + + + G ++NI S+ G+ G Y + K + TK LAL+ + G+ Sbjct: 139 FNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGI 198 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EA 235 VN +SPG + T + E + P+ + +L Q P+GR+G+P EV A FL S +A Sbjct: 199 TVNTVSPGYLATAMVEAV------PQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDA 252 Query: 236 NFCTGIELLVTGGAEL 251 F TG +L + GG + Sbjct: 253 GFVTGADLAINGGMHM 268 >2Q2Q-A nrPDB Length = 255 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 78/237 (32%), Positives = 117/237 (49%), Gaps = 13/237 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--AVFILCDVTQE 66 GK +VTG GIG GI + +GA +V+ + E G AV D++ Sbjct: 4 GKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLSDV 63 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 ++ L + R FG +D +VNNAG H P E+ + + +++ LNL + T+LA Sbjct: 64 AQIEALFALAEREFGGVDILVNNAGIQHVAP--VEQFPLESWDKIIALNLSAVFHGTRLA 121 Query: 126 LPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 LP +R ++ G +INI+S+ G +G YVA K V +TK + L+ + V N I P Sbjct: 122 LPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICP 181 Query: 185 GNIWTPL----WEELAALMPDPRATIREGMLA--QPLGRMGQPAEVGAAAVFLASEA 235 G + TPL ++ AA DP + +LA QP P +G +FL SEA Sbjct: 182 GWVLTPLVQKQIDDRAANGGDPLQA-QHDLLAEKQPSLAFVTPEHLGELVLFLCSEA 237 >3O4R-A nrPDB Length = 261 Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 68/247 (27%), Positives = 123/247 (49%), Gaps = 10/247 (4%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR----ALEQELPGAVFILCDV 63 A KV +VT GIG I R GA VV+ + + L+ E +C V Sbjct: 14 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 73 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + +D + LV+ ++ G +D +V+NA +P + + + + + L++N+ +TK Sbjct: 74 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 133 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAV-PYVATKGAVTAMTKALALDESPYGVRVNCI 182 +P + K G + I S + A + PY +K A+ +TK LA++ +P +RVNC+ Sbjct: 134 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 193 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I T + + + + +++E + + R+G+P + FL SE A++ TG Sbjct: 194 APGLIKTS-FSRMLWMDKEKEESMKETLRIR---RLGEPEDCAGIVSFLCSEDASYITGE 249 Query: 242 ELLVTGG 248 ++V GG Sbjct: 250 TVVVGGG 256 >4CQL-A nrPDB Length = 261 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 73/259 (28%), Positives = 120/259 (46%), Gaps = 22/259 (8%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--------- 55 R + +VTG G GIG + GA V CD D + + + L G Sbjct: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 Query: 56 ---AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLE 112 A F DV++ + L+ + F R VV + + S + +++ Sbjct: 67 GNHAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 Query: 113 LNLLGTYTLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALAL 170 +NL GT+ +T+ A L + +G++INISS+VG +G Y A+K V +T+ A Sbjct: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 Query: 171 DESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVF 230 + +G+R N + PG I TP+ +++ P+ + + P+G +G P +V F Sbjct: 186 ELGRHGIRCNSVLPGFIATPMTQKV------PQKVVDKITEMIPMGHLGDPEDVADVVAF 239 Query: 231 LASE-ANFCTGIELLVTGG 248 LASE + + TG + VTGG Sbjct: 240 LASEDSGYITGTSVEVTGG 258 >4K6F-A nrPDB Length = 255 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 119/250 (47%), Gaps = 15/250 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG--RAL-EQELPGAVFIL--CDVT 64 ++ VVTGG G+G + ++G RVV+ + G R L E G F DV Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVA 71 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK- 123 D + + + +R G +D +VNNAG + + ++ NL + +TK Sbjct: 72 DHDSCQQCIEKIVRDVGPVDILVNNAGI-TRDMTLRKLDKVNWDAVIRTNLDSVFNMTKP 130 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + + + G ++NISS+ G+ G Y A K + TK+LAL+ + GV VN +S Sbjct: 131 VCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNTVS 190 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 PG + T + + P+ + +L Q P GR+G+P EV A +L S EA F TG Sbjct: 191 PGYLATKMVTAI------PQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGS 244 Query: 242 ELLVTGGAEL 251 + + GG + Sbjct: 245 NIAINGGQHM 254 >4KMS-A nrPDB Length = 249 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/246 (29%), Positives = 114/246 (46%), Gaps = 12/246 (4%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC-DVTQEDD 68 ++ +VTGG RGIG N G VV + + A E E + C +V ++ Sbjct: 11 EIAIVTGGTRGIGKATALELKNKGLTVV-ANFFSNYDAAKEMEEKYGIKTKCWNVADFEE 69 Query: 69 VKTLVSETIRRFGR-LDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALP 127 + V E F + + +VNNAG + S Q + ++ +NL + ++ + Sbjct: 70 CRQAVKEIEEEFKKPVSILVNNAGI-TKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVME 128 Query: 128 YLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186 +R + G ++NISS+ GQ Y A K + TKALA + + + VNCI+PG Sbjct: 129 QMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGY 188 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLV 245 I T + + A+ D A I + P R+GQP E+ A FL E A F TG + + Sbjct: 189 IATEM---VGAVPEDVLAKIINSI---PKKRLGQPEEIARAVAFLVDENAGFITGETISI 242 Query: 246 TGGAEL 251 GG + Sbjct: 243 NGGHNM 248 >2ZAT-A nrPDB Length = 260 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/249 (30%), Positives = 124/249 (49%), Gaps = 18/249 (7%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRA---LEQELPGAVFILCDVTQ 65 KV +VT GIG I R GA VV+ K E+ R L+ E +C V + Sbjct: 15 KVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGK 74 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 +D + LV+ + G +D +V+NA +P + + + + ++L +N+ T +TK Sbjct: 75 AEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAV 134 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAV-PYVATKGAVTAMTKALALDESPYGVRVNCISP 184 +P + K G + I S VGA + PY +K A+ +TK LA++ +P +RVNC++P Sbjct: 135 VPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAP 194 Query: 185 GNIWTP----LWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCT 239 G I T LW + A + ++E + + R+G P + FL SE A++ T Sbjct: 195 GLIKTNFSQVLWMDKA-----RKEYMKESL---RIRRLGNPEDCAGIVSFLCSEDASYIT 246 Query: 240 GIELLVTGG 248 G ++V GG Sbjct: 247 GETVVVGGG 255 >3R3S-A nrPDB Length = 294 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 123/254 (48%), Gaps = 12/254 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVIC-----DKDESGGRALEQEL-PGAVFI 59 R + +VTGG GIG A+ GA V I ++D +AL +E AV + Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 D++ E ++LV + G LD + AG ++ +++ F+Q +N+ + Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALF 165 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 +T+ A+P L K ++I SS+ + Y ATK A+ ++ LA + G+RV Sbjct: 166 WITQEAIPLLPKG-ASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRV 224 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N ++PG IWT L +++ + I + P+ R GQPAE+ V+LAS E+++ Sbjct: 225 NIVAPGPIWTAL--QISGGQTQDK--IPQFGQQTPMKRAGQPAELAPVYVYLASQESSYV 280 Query: 239 TGIELLVTGGAELG 252 T V GG LG Sbjct: 281 TAEVHGVCGGEHLG 294 >3ZV3-A nrPDB Length = 281 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 118/256 (46%), Gaps = 16/256 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVT 64 + G+V ++TGG G+G +V FV GARV + DK R LE G AV ++ DV Sbjct: 2 KLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVR 61 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAG----HHPPPQRPEETSAQGFRQLLELNLLGTYT 120 D K + FG++D ++ NAG PE+ F + +N+ G Sbjct: 62 SLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYIH 121 Query: 121 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 K LP L S+G+V+ S G Y ATK AV + + +A + +P+ VRVN Sbjct: 122 AVKACLPALVSSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH-VRVN 180 Query: 181 CISPGNIWTPLWEELAALMPD------PRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 ++PG + T L + + + P A + + +L P+GRM E A VF A+ Sbjct: 181 GVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVL--PIGRMPALEEYTGAYVFFATR 238 Query: 235 ANF--CTGIELLVTGG 248 + TG L GG Sbjct: 239 GDSLPATGALLNYDGG 254 >3LYL-A nrPDB Length = 247 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 116/247 (46%), Gaps = 17/247 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF----ILCDVTQ 65 KV +VTG RGIG + A + GA VV ++ E + F ++ +++ Sbjct: 6 KVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNISD 65 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + ++ +E +D +VNNAG R E Q ++ NL + ++K Sbjct: 66 IESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQ---SVINTNLSSIFRMSK 122 Query: 124 LALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 + ++K G +I+I S+VG+ G Y A K V +K+LA + + + VN + Sbjct: 123 ECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNVV 182 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 +PG I T + ++L AT P G++G+P ++ AA FLAS EA + TG Sbjct: 183 APGFIATDMTDKLTDEQKSFIAT------KIPSGQIGEPKDIAAAVAFLASEEAKYITGQ 236 Query: 242 ELLVTGG 248 L V GG Sbjct: 237 TLHVNGG 243 >1CYD-A nrPDB Length = 244 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 123/235 (52%), Gaps = 11/235 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 ++G +VTG G+GIG V+A SGA+VV + S +L +E PG + D+ Sbjct: 5 FSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDW 64 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 D + + + G +D +VNNA Q E + + F + +NL + ++++ Sbjct: 65 DATE----KALGGIGPVDLLVNNAAL-VIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVA 119 Query: 127 PYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 + R G+++N+SS+V + + Y +TKGA+T +TKA+A++ P+ +RVN ++P Sbjct: 120 RDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNP 179 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCT 239 + T + ++++A DP R+ PL + + +V + +FL S+ + T Sbjct: 180 TVVLTDMGKKVSA---DPEFA-RKLKERHPLRKFAEVEDVVNSILFLLSDRSAST 230 >4IS3-A nrPDB Length = 268 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 67/235 (28%), Positives = 116/235 (49%), Gaps = 20/235 (8%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVIC-DKDESGGRAL--------EQELPGAVFIL 60 KV ++TGG RGIG + F+++GA+V I + E AL E+E+ G Sbjct: 26 KVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLG---FA 82 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 D+T D V V + +++GRLD ++NNAG S + F+ ++++N+ G + Sbjct: 83 PDLTSRDAVMAAVGQVAQKYGRLDVMINNAGI-TSNNVFSRVSEEEFKHIMDINVTGVFN 141 Query: 121 LTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 A ++ ++ G +IN +S+ G G V Y A+K +V +T L + +RV Sbjct: 142 GAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIRV 201 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 ++PG + T + +P + + A P+ RM +P E+ +FLAS+ Sbjct: 202 VGVAPGVVNTDMTN------GNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASD 250 >3WYE-A nrPDB Length = 256 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 120/252 (47%), Gaps = 15/252 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP----GAVFILCDVTQ 65 KV +VTG G+GIG I V G V I D +++ +A+ E+ AV + DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKL 124 D V V + + G D +VNNAG +P E + + +Q+ +N+ + + Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAG--IAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 120 Query: 125 ALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 A+ +K G +IN +S+ G Y TK AV +T+ A D +P G+ VN Sbjct: 121 AVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 183 SPGNIWTPLWEELAALMPDPRA-----TIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236 PG + T +WE++ A + +E + LGR P +V FLAS +++ Sbjct: 181 CPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSD 240 Query: 237 FCTGIELLVTGG 248 + TG LL+ GG Sbjct: 241 YMTGQSLLIDGG 252 >2C07-A nrPDB Length = 285 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 64/247 (25%), Positives = 123/247 (49%), Gaps = 15/247 (6%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF----ILCDVT 64 KV +VTG GRGIG I + S + V+ + + ++ E+ + DV+ Sbjct: 44 NKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVS 103 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK- 123 +++++ ++++ + +D +VNNAG + + + +L NL + +T+ Sbjct: 104 KKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDE-WEDVLRTNLNSLFYITQP 162 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 ++ + G +INISS+VG G Y ++K V TK+LA + + + VN I+ Sbjct: 163 ISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIA 222 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASEAN-FCTGI 241 PG I + + ++++ I++ +++ P GRMG P EV A FL+S+ + + G Sbjct: 223 PGFISSDMTDKIS-------EQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGR 275 Query: 242 ELLVTGG 248 ++ GG Sbjct: 276 VFVIDGG 282 >5YSS-A nrPDB Length = 256 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 121/239 (50%), Gaps = 19/239 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVIC---DKDESGGRALEQ--ELPGAVFILCDV 63 GK +VTG GIG GI + +GA +++ D D + A+ Q + PG + D+ Sbjct: 5 GKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVD-AAKDAVAQYGKTPG--YHGADL 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 + E + ++ FG +D ++NNAG H P E + ++ +NL + T Sbjct: 62 SDEAQIADMMRYAESEFGGVDILINNAGIQHVSP--IETFPVDKWNAIIAINLSSVFHTT 119 Query: 123 KLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 +LALP +R ++ G +INI+S+ G + + YVA K V +TK +AL+ + + N Sbjct: 120 RLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNA 179 Query: 182 ISPGNIWTPLWEEL----AALMPDPRATIREGMLA--QPLGRMGQPAEVGAAAVFLASE 234 + PG + TPL ++ A +P A R+ +LA QP P ++G A+FL S+ Sbjct: 180 LCPGWVLTPLVQQQIDKRIAEGAEPEAA-RDALLAEKQPSREFVTPEQLGNLALFLCSD 237 >3V2G-A nrPDB Length = 271 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 82/270 (30%), Positives = 124/270 (45%), Gaps = 44/270 (16%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVR-----------AFVNSG--ARVVICDKDESGGR 47 M T AGK VTGG RGIGA I + +VN+ A+ V+ + +++GGR Sbjct: 23 MMTSISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGR 82 Query: 48 ALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQG 106 AV I D + ++ + ET+ G LD +VN+AG H P EET+ Sbjct: 83 --------AVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPL--EETTVAD 132 Query: 107 FRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP------YVATKGA 160 F +++ +N + + A +L G +I I S + A+ VP Y A+K A Sbjct: 133 FDEVMAVNFRAPFVAIRSASRHLGDG-GRIITIGSNL-----AELVPWPGISLYSASKAA 186 Query: 161 VTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQ 220 + +TK LA D P G+ VN + PG+ T ++ D RE + G G+ Sbjct: 187 LAGLTKGLARDLGPRGITVNIVHPGSTDT----DMNPADGDHAEAQRERI---ATGSYGE 239 Query: 221 PAEVGAAAVFLAS-EANFCTGIELLVTGGA 249 P ++ +LA + F TG L + GGA Sbjct: 240 PQDIAGLVAWLAGPQGKFVTGASLTIDGGA 269 >3V2H-A nrPDB Length = 281 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 126/258 (48%), Gaps = 25/258 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICD---KDESGGRALEQELPG-----AVFILC 61 K V+TG GIG I R +GA +V+ DE R + E+ G + Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEI--RTVTDEVAGLSSGTVLHHPA 83 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 D+T+ ++ +++ RFG D +VNNAG ++ E+ + + +++ +NL ++ Sbjct: 84 DMTKPSEIADMMAMVADRFGGADILVNNAGVQFV-EKIEDFPVEQWDRIIAVNLSSSFHT 142 Query: 122 TKLALPYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + A+P ++K G +INI+S G + YVA K + +TK +AL+ + GV VN Sbjct: 143 IRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVN 202 Query: 181 CISPGNIWTPLWEELAALMPDPRAT--------IREGML-AQPLGRMGQPAEVGAAAVFL 231 I PG + TPL E+ +PD T I E ML QP + +V + A++L Sbjct: 203 SICPGYVLTPLVEK---QIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYL 259 Query: 232 A-SEANFCTGIELLVTGG 248 A +A TG + + GG Sbjct: 260 AGDDAAQITGTHVSMDGG 277 >1O5I-A nrPDB Length = 249 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/250 (27%), Positives = 121/250 (48%), Gaps = 21/250 (8%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 M G R G V+V RGIG + GA V IC ++E + G +++ Sbjct: 13 MELGIRDKG--VLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKR-----SGHRYVV 65 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 CD+ ++ D L+ E ++ +D +V NAG P +E + + F++ ++ L Sbjct: 66 CDLRKDLD---LLFEKVKE---VDILVLNAGG-PKAGFFDELTNEDFKEAIDSLFLNMIK 118 Query: 121 LTKLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + + LP ++ K G ++ I+S + + A+T K L+ + +PYG+ V Sbjct: 119 IVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITV 178 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238 NC++PG WT E + L+ + + E + P+ RM +P E+ + FL SE A++ Sbjct: 179 NCVAPG--WTET-ERVKELLSEEKKKQVESQI--PMRRMAKPEEIASVVAFLCSEKASYL 233 Query: 239 TGIELLVTGG 248 TG ++V GG Sbjct: 234 TGQTIVVDGG 243 >3EZL-A nrPDB Length = 256 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 119/251 (47%), Gaps = 16/251 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL---EQELPGAVFILC--DVT 64 ++ VTGG GIG I + G RVV S R +Q+ G F +V Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVG 73 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 D K + G +D +VNNAG + T + ++ +++ NL + +TK Sbjct: 74 DWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTR-EDWQAVIDTNLTSLFNVTKQ 132 Query: 125 ALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + + + G +INISS+ G GQ Y K + T +LA + + GV VN +S Sbjct: 133 VIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVS 192 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 PG I T + + A+ PD + E ++A P+ R+G P E+G+ +LAS E+ F TG Sbjct: 193 PGYIGTDM---VKAIRPD----VLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGA 245 Query: 242 ELLVTGGAELG 252 + + GG +G Sbjct: 246 DFSLNGGLHMG 256 >3RWB-A nrPDB Length = 247 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 77/247 (31%), Positives = 115/247 (46%), Gaps = 10/247 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVT 64 R AGK +VTG +GIG I GA V++ D + G +A + A I D++ Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADIS 62 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 VK L +E G +D +VNNA P ++ +R+++++NL GT+ +T+ Sbjct: 63 DPGSVKALFAEIQALTGGIDILVNNASIVPFVAW-DDVDLDHWRKIIDVNLTGTFIVTRA 121 Query: 125 ALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 +R + G VI+I+S G YVA KG V T+ALA + Y + N + Sbjct: 122 GTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAV 181 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 +PG I + + P A ML Q + GQP + FLAS +A + TG Sbjct: 182 TPGLIES----DGVKASPHNEAFGFVEML-QAMKGKGQPEHIADVVSFLASDDARWITGQ 236 Query: 242 ELLVTGG 248 L V G Sbjct: 237 TLNVDAG 243 >3D3W-A nrPDB Length = 244 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 75/245 (30%), Positives = 122/245 (49%), Gaps = 14/245 (5%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 AG+ V+VTG G+GIG G V+A +GARVV + ++ +L +E PG + D+ + Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWE 65 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALP 127 + + G +D +VNNA Q E + + F + E+NL ++++ Sbjct: 66 ATE----RALGSVGPVDLLVNNAA-VALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120 Query: 128 YL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 L R G ++N+SS Y +TKGA+ +TK +AL+ P+ +RVN ++P Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIEL 243 + T + + A DP + ML + PLG+ + V A +FL S+ + TG L Sbjct: 181 VVMTSMGQ---ATWSDPHKA--KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTL 235 Query: 244 LVTGG 248 V GG Sbjct: 236 PVEGG 240 >2PH3-A nrPDB Length = 245 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 116/247 (46%), Gaps = 21/247 (8%) Query: 13 VVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL------PGAVFILCDVTQE 66 ++TG RGIG I G + I E P + ++ + Sbjct: 5 LITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANLLEA 64 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 + LV + G LD +VNNAG R ++ + + +LE NL + T+ Sbjct: 65 EAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKD---EDWEAVLEANLSAVFRTTRE 121 Query: 125 ALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 A+ + K++ G ++NI+S+VG +G YVA+K + T+A+A + + G+ VN ++ Sbjct: 122 AVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVA 181 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 PG I T + E L P+ ++E L Q P GR G+P EV A FL SE A + TG Sbjct: 182 PGFIETEMTERL------PQ-EVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQ 234 Query: 242 ELLVTGG 248 L V GG Sbjct: 235 TLCVDGG 241 >3UF0-A nrPDB Length = 273 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 80/250 (32%), Positives = 122/250 (48%), Gaps = 19/250 (7%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP----GAVFILCDV 63 AG+ VVTG G GIG I + +GA V+ + + G + + E+ A ++ D+ Sbjct: 30 AGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTD-GVKEVADEIADGGGSAEAVVADL 88 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 + V+E + R+D +VNNAG P EE S +R++L +NL + L Sbjct: 89 ADLEGAAN-VAEELAATRRVDVLVNNAGIIARAPA---EEVSLGRWREVLTVNLDAAWVL 144 Query: 122 TK-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 ++ L G ++ I+S++ G Y A+K AV +T+ALA + + GV VN Sbjct: 145 SRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVN 204 Query: 181 CISPGNIWTPLWEELAAL-MPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238 ++PG + T AAL D RA E P GR P ++ AVFLAS+ A++ Sbjct: 205 ALAPGYVVTA---NTAALRADDERAA--EITARIPAGRWATPEDMVGPAVFLASDAASYV 259 Query: 239 TGIELLVTGG 248 G L V GG Sbjct: 260 HGQVLAVDGG 269 >5B1Y-A nrPDB Length = 270 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 77/228 (33%), Positives = 112/228 (49%), Gaps = 13/228 (5%) Query: 13 VVTGGGRGIGAGIVRAFVNSGARVVICDK------DESGGRALEQELPGAVFILCDVTQE 66 +VTGG RGIG V F G VVI K +++ A P A + DV Sbjct: 27 LVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGDP 86 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 D V + S L+ +VN AG EETS + + L +NL G Y +TKL L Sbjct: 87 DSVTEMSSRVGELIPHLNVLVNAAGVLQLGG-IEETSISEWEETLRVNLTGVYLVTKLLL 145 Query: 127 PYLRKSQ-GNVINISSLVGAIGQAQA-VPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 P LRK++ +++N++S+ G G A V Y A+K V +TK LA+ + YG+RVN ++P Sbjct: 146 PLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAP 205 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA 232 + T + + + P R L PL + +P +V A +FLA Sbjct: 206 SFVETDM---TRSFLDTPEKRERIASL-HPLKIILKPEDVAEAILFLA 249 >6NRP-A nrPDB Length = 263 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 74/247 (29%), Positives = 121/247 (48%), Gaps = 22/247 (8%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKD-ESGGRALEQELP----GAVFILCDVTQE 66 ++VTG RGIG I +G V + + ++ + QE+ + +++ DV + Sbjct: 27 ILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVNER 86 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK-LA 125 V+ ++ + + + G VV NAG P T Q + +++ +L G Y + K L Sbjct: 87 QTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTD-QDWDEVISTSLDGFYNVLKPLI 145 Query: 126 LP--YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 +P +LRK G ++ +SS+ G +G V Y A K + TKALAL+ + + VNC++ Sbjct: 146 MPMIHLRKG-GRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 PG I T + + ++E L PL RMGQ EV + FL S EA++ T Sbjct: 205 PGLIETEMVTD----------EVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQ 254 Query: 242 ELLVTGG 248 + V GG Sbjct: 255 VISVNGG 261 >3WTC-A nrPDB Length = 262 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 121/255 (47%), Gaps = 17/255 (6%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD--KDESGGRALEQELPG--AVFILCDV 63 +GK+ VTG +GIG I GA V++ D +D A E E G AV + D+ Sbjct: 7 SGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTADI 66 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 + D ++ +++ + G LD +VNNAG P E ++ +N+ G Sbjct: 67 SNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAE---IEKIFSINVQGVLWG 123 Query: 122 TKLALPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + A ++ ++G +IN S+ G G Y ATK AV A+T++ A + + G+ V Sbjct: 124 MQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITV 183 Query: 180 NCISPGNIWTPLWEELAALMPDPR-----ATIREGMLAQPLGRMGQPAEVGAAAVFL-AS 233 N PG + T +W + M + AT ++ + LGR+ +V +L +S Sbjct: 184 NSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLSSS 243 Query: 234 EANFCTGIELLVTGG 248 +A++ TG +L+ GG Sbjct: 244 DADYMTGQSVLIDGG 258 >2FWM-X nrPDB Length = 250 Score = 86.7 bits (213), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 125/252 (49%), Gaps = 13/252 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 ++GK V VTG G+GIG AFV +GA+V D+ + +++ P A ++ DV Sbjct: 5 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFT-----QEQYPFATEVM-DVADA 58 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 V + + RLD +VN AG ++ S + ++Q +N+ G + L + + Sbjct: 59 AQVAQVCQRLLAETERLDALVNAAGILRMGA-TDQLSKEDWQQTFAVNVGGAFNLFQQTM 117 Query: 127 PYLRKSQGN-VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 R+ +G ++ ++S + Y A+K A+ ++ ++ L+ + GVR N +SPG Sbjct: 118 NQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 177 Query: 186 NIWTP----LWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240 + T LW A R + L PLG++ +P E+ +FLAS+ A+ T Sbjct: 178 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 237 Query: 241 IELLVTGGAELG 252 +++V GG+ LG Sbjct: 238 QDIVVDGGSTLG 249 >1DOH-A nrPDB Length = 283 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 75/266 (28%), Positives = 126/266 (47%), Gaps = 38/266 (14%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI--CDKDESGGR---ALEQELPGAVFILCDV 63 GKV +VTG GRGIG + G +V++ + ES A+++ A + +V Sbjct: 29 GKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANV 88 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG----HHPPPQRPEETSAQGFRQLLELNLLGTY 119 +D+ + E ++ FG+LD V +N+G H PEE F ++ +N G + Sbjct: 89 GVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEE-----FDRVFTINTRGQF 143 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP----YVATKGAVTAMTKALALDESPY 175 + + A +L G +I + S+ G QA+AVP Y +KGA+ + +A+D + Sbjct: 144 FVAREAYKHLEIG-GRLILMGSITG---QAKAVPKHAVYSGSKGAIETFARCMAIDMADK 199 Query: 176 GVRVNCISPGNIWTPLW-----------EELAALMPDPRATIREGMLAQPLGRMGQPAEV 224 + VN ++PG I T ++ E L+ D A ++ PL R+G P ++ Sbjct: 200 KITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQ----WSPLRRVGLPIDI 255 Query: 225 GAAAVFLAS-EANFCTGIELLVTGGA 249 FLAS + + TG + + GGA Sbjct: 256 ARVVCFLASNDGGWVTGKVIGIDGGA 281 >1UZM-A nrPDB Length = 247 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 118/251 (47%), Gaps = 20/251 (7%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF-ILCDVTQ 65 + + V+VTGG RGIG I + G +V + + P +F + DVT Sbjct: 13 FVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGA--------PKGLFGVEVDVTD 64 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 D V + G ++ +V+NAG T + F +++ NL G + + + A Sbjct: 65 SDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEK-FEKVINANLTGAFRVAQRA 123 Query: 126 LPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 +++++ G +I I S+ G G Y A+K V M +++A + S V N ++P Sbjct: 124 SRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP 183 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242 G I T + L D R I++G L P R+G PAEV FLASE A++ +G Sbjct: 184 GYIDTDMTRAL-----DER--IQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAV 236 Query: 243 LLVTGGAELGY 253 + V GG +G+ Sbjct: 237 IPVDGGMGMGH 247 >3VZS-A nrPDB Length = 257 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 119/251 (47%), Gaps = 16/251 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVI-CDKDE-SGGRALEQELP-GAVFILC--DVT 64 ++ VTGG GIG I + G RVV C + + LEQ+ G FI +V Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 D KT + G +D ++NNAG + T A + +++ NL + +TK Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRAD-WDAVIDTNLTSLFNVTKQ 133 Query: 125 ALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + + + G ++NISS+ G GQ Y K + T ALA + + GV VN +S Sbjct: 134 VIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVS 193 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 PG I T + + + R + + ++A P+ R+G P E+ + +L+S E+ F TG Sbjct: 194 PGYIATDMVKAI-------RQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGA 246 Query: 242 ELLVTGGAELG 252 + + GG +G Sbjct: 247 DFSLNGGLHMG 257 >3A28-C nrPDB Length = 258 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 119/254 (46%), Gaps = 17/254 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICD---KDESGG---RALEQELPGAVFILCDV 63 KV +VTGG +GIG GI G + + D ++E + +E AVF+ DV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 T + + + + E + G D +VNNAG P E + + +Q+ +N+ + Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLL--EVTEEDLKQIYSVNVFSVFFGI 120 Query: 123 KLALPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + A + +G +IN +S+ G Y TK AV +T+A A + +P G VN Sbjct: 121 QAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVN 180 Query: 181 CISPGNIWTPLWEELAALMPDPRA-----TIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 +PG + T +WE++ A + +E + LGR P +V FLASE Sbjct: 181 AYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASEN 240 Query: 235 ANFCTGIELLVTGG 248 +N+ TG +LV GG Sbjct: 241 SNYVTGQVMLVDGG 254 >4Z9Y-A nrPDB Length = 253 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 69/247 (27%), Positives = 128/247 (51%), Gaps = 14/247 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI--LCDVTQE 66 GKV ++TG G+G G+ +G +V + E + G F+ D++ Sbjct: 10 GKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADMSNV 69 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE--ETSAQGFRQLLELNLLGTYTLTK- 123 LV + + FG +D +VNNAG +R + E S + + ++ LN+ + +++ Sbjct: 70 SGHAELVEKAVAEFGHVDILVNNAG---IIRREDAIEFSEKNWDDVMNLNIKSVFFMSQT 126 Query: 124 LALPYLRKSQG-NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 +A ++++ +G +INI+S++ G + Y A+K AV +T+ +A + + +G+ VN I Sbjct: 127 VARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNAI 186 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEA-NFCTGI 241 +PG + T ++L A + R+ +E + P GR G P ++ +VFLAS A ++ G Sbjct: 187 APGYMATNNTQQLRA--DEERS--KEILDRIPAGRWGLPQDLMGPSVFLASSASDYINGY 242 Query: 242 ELLVTGG 248 + V GG Sbjct: 243 TIAVDGG 249 >4CR6-A nrPDB Length = 271 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 121/252 (48%), Gaps = 15/252 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R AGK +VTG GIG V A++ GA VV D A E PGA+ I CD+ Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLA-ATRYEEPGAIPIACDLAD 70 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + +++ + R G LD +V + S + + +++N+ GT+ + Sbjct: 71 RAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAG 130 Query: 126 LPYLRKS-------QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + +I I S+ + + +A YVA KG V +T+A+A+D + +G+ Sbjct: 131 ARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGIL 190 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-AN 236 VN I+PG + +PR + E +L + LGR G P EV AAVFLA + ++ Sbjct: 191 VNMIAPGPVDVTGNNT---GYSEPR--LAEQVLDEVALGRPGLPEEVATAAVFLAEDGSS 245 Query: 237 FCTGIELLVTGG 248 F TG + + GG Sbjct: 246 FITGSTITIDGG 257 >3T7C-A nrPDB Length = 299 Score = 83.6 bits (205), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 73/275 (26%), Positives = 124/275 (45%), Gaps = 30/275 (10%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD--------------KDESGGRALEQ 51 + GKV +TG RG G GA ++ D D+ + Sbjct: 25 KVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQV 84 Query: 52 ELPGAVFIL--CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 E G I DV D ++ V + + + GRLD V+ NA R + +R Sbjct: 85 EALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRD 144 Query: 110 LLELNLLGTYTLTKLALPYLR--KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA 167 ++++NL G + ++A+P++ K G+++ SS+ G G Y+A+K + + + Sbjct: 145 MIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRT 204 Query: 168 LALDESPYGVRVNCISPGNIWTP-LWEELAALMPDP---RATIREGMLAQ------PLGR 217 +AL+ P +RVN + P ++ TP L E M P T+ + +A P+ Sbjct: 205 MALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIPY 264 Query: 218 MGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 251 + +PA++ A +FL S +A + TG+ L V GGA L Sbjct: 265 V-EPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >5OVJ-A nrPDB Length = 256 Score = 83.6 bits (205), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 112/250 (44%), Gaps = 18/250 (7%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + + V+VTGG RGIG I R G +V + + G +L G + CDVT Sbjct: 22 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHR----GSGAPDDLFG---VQCDVTDS 74 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 V E G ++ +V NAG T + F +++ NL G + + A Sbjct: 75 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEER-FEEVINTNLTGAFRCAQRAS 133 Query: 127 PYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + RK G +I I S+ G G Y A K + M ++++ + + GV N ++PG Sbjct: 134 RTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPG 193 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIEL 243 I T + L D R I+ G L P R+G EV A FLASE A++ G + Sbjct: 194 YIDTEMTRAL-----DER--IQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVI 246 Query: 244 LVTGGAELGY 253 V GG +G+ Sbjct: 247 PVDGGMGMGH 256 >5OVL-A nrPDB Length = 300 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 112/250 (44%), Gaps = 18/250 (7%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + + V+VTGG RGIG I R G +V + + G +L G + CDVT Sbjct: 66 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHR----GSGAPDDLFG---VQCDVTDS 118 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 V E G ++ +V NAG T + F +++ NL G + + A Sbjct: 119 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEER-FEEVINTNLTGAFRCAQRAS 177 Query: 127 PYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + RK G +I I S+ G G Y A K + M ++++ + + GV N ++PG Sbjct: 178 RTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPG 237 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIEL 243 I T + L D R I+ G L P R+G EV A FLASE A++ G + Sbjct: 238 YIDTEMTRAL-----DER--IQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVI 290 Query: 244 LVTGGAELGY 253 V GG +G+ Sbjct: 291 PVDGGMGMGH 300 >3KZV-A nrPDB Length = 254 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 53/186 (28%), Positives = 97/186 (52%), Gaps = 5/186 (2%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI--CDKDESGGRALEQELPGAVF-ILCDVTQ 65 GKV++VTG RGIG IV + V+ + E+ + L+++ F ++ D+T+ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + +K LV+ ++ G++D +V NAG P Q E +++L ++N +L +A Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIA 121 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 LP L+K+ GNV+ +SS + + Y ++K A+ LA +E V+ ++PG Sbjct: 122 LPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANEERQ--VKAIAVAPG 179 Query: 186 NIWTPL 191 + T + Sbjct: 180 IVDTDM 185 >3U5T-A nrPDB Length = 267 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 77/232 (33%), Positives = 109/232 (46%), Gaps = 20/232 (8%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--------AVFILC 61 KV +VTG RGIGA I + G VVI + +G A +E+ G A+ Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVI---NYAGKAAAAEEVAGKIEAAGGKALTAQA 84 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DV+ V+ L + FG +D +VNNAG P E A F +++ +NL GT+ Sbjct: 85 DVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAV-FDRVIAVNLKGTFNT 143 Query: 122 TKLALPYLRKSQGNVINIS-SLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + A LR G +IN+S S VG + + + Y A K V AMT L+ + + VN Sbjct: 144 LREAAQRLRVG-GRIINMSTSQVGLLHPSYGI-YAAAKAGVEAMTHVLSKELRGRDITVN 201 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA 232 ++PG T L+ E R LA PL R+G P ++ A FLA Sbjct: 202 AVAPGPTATDLFLE----GKSDEVRDRFAKLA-PLERLGTPQDIAGAVAFLA 248 >3UVE-A nrPDB Length = 286 Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 72/281 (25%), Positives = 121/281 (43%), Gaps = 38/281 (13%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVV---ICDKDESGGRALEQELPGA------ 56 R GKV VTG RG G GA ++ IC +G ++ +P + Sbjct: 8 RVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAG--VVDTAIPASTPEDLA 65 Query: 57 -------------VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETS 103 V DV D +K V + + GRLD +V NAG ++TS Sbjct: 66 ETADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTS 125 Query: 104 AQGFRQLLELNLLGTYTLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAV 161 + + +++++NL G + K +P++ G++I SS+ G YVA K V Sbjct: 126 EEDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGV 185 Query: 162 TAMTKALALDESPYGVRVNCISPGNIWTPLWE----------ELAALMPDPRATIREGML 211 + +A ++ + +RVN + P ++ TP+ +L PD A I + Sbjct: 186 VGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFH 245 Query: 212 AQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 251 P+ + +P ++ A +F AS EA + TG+ L + G+ L Sbjct: 246 TLPIPWV-EPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >1H5Q-A nrPDB Length = 265 Score = 80.1 bits (196), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 78/263 (29%), Positives = 123/263 (46%), Gaps = 34/263 (12%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE-QELPGAVF------I 59 + K ++VTGG RGIG RA +GA V + + S A+E E G F Sbjct: 12 FVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYR--SAADAVEVTEKVGKEFGVKTKAY 69 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRP-EETSAQGFRQLLELNLLGT 118 CDV+ D V + + G + ++ NAG +P E + + F + ++N+ G Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPISGLIANAG--VSVVKPATELTHEDFAFVYDVNVFGV 127 Query: 119 Y-TLTKLALPYLRKSQ-----------GNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 + T +A +L+K Q +IN SSL G++ Q V Y ++K A + + K Sbjct: 128 FNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQ---VFYNSSKAACSNLVK 184 Query: 167 ALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEV-G 225 LA + + G+RVN +SPG + T + + D +A+ PL R QP E+ G Sbjct: 185 GLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQAS------NIPLNRFAQPEEMTG 238 Query: 226 AAAVFLASEANFCTGIELLVTGG 248 A + L+ A + TG E + GG Sbjct: 239 QAILLLSDHATYMTGGEYFIDGG 261 >4IIV-A nrPDB Length = 267 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 113/251 (45%), Gaps = 24/251 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARV-VICDKDESGGRALEQELPGAV--------FIL 60 + V+VTG +GIG I R G + V +D +G QE A+ + Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGA----QETLNAIVANGGNGRLLS 82 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DV + + ++ I + G VV+NAG P S + ++ NL Y Sbjct: 83 FDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPA-LSNDDWDAVIHTNLDSFYN 141 Query: 121 LTK-LALPYLRKSQG-NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + +P + QG +I +SS+ G +G V Y A K + TKALA++ + + Sbjct: 142 VIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKIT 201 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VNCI+PG I T + E + ++E M P+ RMGQ EV A +L S+ A + Sbjct: 202 VNCIAPGLIDTGMIEM-------EESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGY 254 Query: 238 CTGIELLVTGG 248 T + + GG Sbjct: 255 VTRQVISINGG 265 >3GDF-A nrPDB Length = 267 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 72/252 (28%), Positives = 118/252 (46%), Gaps = 20/252 (7%) Query: 9 GKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGG-----RALEQELP-GAVFIL 60 GKVVVVTG G +G+G R GA V I + G + LE+ A Sbjct: 20 GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYK 79 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 C V + + LV + + FG++D + NAG + S + + +++++L GT+ Sbjct: 80 CQVDSYESCEKLVKDVVADFGQIDAFIANAG-ATADSGILDGSVEAWNHVVQVDLNGTFH 138 Query: 121 LTKLALPYLR-KSQGNVINISSLVGAIGQ--AQAVPYVATKGAVTAMTKALALDESPYGV 177 K + + + G+++ +S+ G I + Y K M ++LA + + Sbjct: 139 CAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEWRDF-A 197 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEAN- 236 RVN ISPG I T L+ +P + M+ P+GR G E+ A V+ AS+A+ Sbjct: 198 RVNSISPGYIDTG----LSDFVPKETQQLWHSMI--PMGRDGLAKELKGAYVYFASDAST 251 Query: 237 FCTGIELLVTGG 248 + TG +LL+ GG Sbjct: 252 YTTGADLLIDGG 263 >1W73-A nrPDB Length = 302 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 64/198 (32%), Positives = 98/198 (49%), Gaps = 11/198 (5%) Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNA-GHHPPPQRPEETSAQGFRQLLELNLLG 117 I CDV D V+ VSE I+ G + V+NNA G+ P E S ++ + ++ L G Sbjct: 81 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISP--TERLSPNAWKTITDIVLNG 138 Query: 118 TYTLTKLALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 T +T L K+Q ++I+++ G VP + K V AM+K+LA + Y Sbjct: 139 TAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKY 198 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE 234 G+R N I PG P+ + A DP T + M+ + P GR+G E+ A FL S+ Sbjct: 199 GMRFNVIQPG----PIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 254 Query: 235 -ANFCTGIELLVTGGAEL 251 A++ G + GG E+ Sbjct: 255 YASWINGAVIKFDGGEEV 272 >5O3Z-A nrPDB Length = 263 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 72/261 (27%), Positives = 117/261 (44%), Gaps = 30/261 (11%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG------AVFILCDV 63 +V VV GGG+ +GA + +G V + D +ES L + A D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAG--HHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 T E V+ L FGR D +V +AG P + T F L++NL+G + Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTD---FDLSLQVNLVGYFLC 123 Query: 122 TKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 ++ + + +G +I I+S G +G Y A K +T++LALD + YG+ V Sbjct: 124 SREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITV 183 Query: 180 NCISPGNIW-TPLWEELAALMPDPRATIREGMLAQ----------PLGRMGQPAEVGAAA 228 + + GN+ +P+++ L P+ + G+ + PL R +V Sbjct: 184 HSLMLGNLLKSPMFQSLL-----PQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVL 238 Query: 229 VFLASE-ANFCTGIELLVTGG 248 +F AS+ A +CTG + VTGG Sbjct: 239 LFYASDKAAYCTGQSINVTGG 259 >4DRY-A nrPDB Length = 281 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 44/141 (31%), Positives = 70/141 (49%), Gaps = 3/141 (2%) Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 ++CDV D V L + F RLD +VNNAG + PP EE + + + ++ NL G Sbjct: 88 VVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGA 147 Query: 119 YTLTKLALPYLRKSQ---GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 + T+ A ++ G +IN S+ + + PY ATK A+T +TK+ ALD + Sbjct: 148 FLCTQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMH 207 Query: 176 GVRVNCISPGNIWTPLWEELA 196 + I GN T + ++ Sbjct: 208 DIACGQIDIGNAATDMTARMS 228 >5EJ2-A nrPDB Length = 308 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 70/278 (25%), Positives = 125/278 (44%), Gaps = 36/278 (12%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD---------------KDESGGRALE 50 R AGKV ++G RG G GA ++ D +D + L Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 51 QELPGAVFIL-CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 ++L + DV + +K+ V + + GRLD +V NAG ++ + ++ Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQD 153 Query: 110 LLELNLLGTYTLTKLALPY-LRKSQGNVINISSLVGAIGQAQAVP----YVATKGAVTAM 164 ++++NL G + K +P+ L +G I ++S ++G +A P Y+A K V + Sbjct: 154 MIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTS---SVGGRKAYPNTGHYIAAKHGVIGL 210 Query: 165 TKALALDESPYGVRVNCISPGNIWTPL----------WEELAALMPDPRATIREGMLAQP 214 +A A++ P+ +RVN + P + T + +L PD A I + M P Sbjct: 211 MRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLP 270 Query: 215 LGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 251 + + +++ A +FLAS E+ + TG+ L V G+ L Sbjct: 271 VPWV-DASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >3PXX-A nrPDB Length = 287 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 80/288 (27%), Positives = 116/288 (40%), Gaps = 47/288 (16%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD---------------KD-ESGGRAL 49 R KVV+VTGG RG G GA +++ D +D E G + Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 50 EQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 E+ A DV V ++ + FG+LD VV NAG P Q F Sbjct: 67 EKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICP---LGAHLPVQAFAD 123 Query: 110 LLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAI-----------GQAQAVPYVATK 158 +++ +G ALPYL S ++I S+ G I Y K Sbjct: 124 AFDVDFVGVINTVHAALPYL-TSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAK 182 Query: 159 GAVTAMTKALALDESPYGVRVNCISPGNIWT------PLWEELAALMPDPRATIR-EGML 211 V + T LA +P +R N I P N+ T P++ + PD A R + +L Sbjct: 183 QLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQ---FRPDLEAPSRADALL 239 Query: 212 AQP-LGRMGQP----AEVGAAAVFLAS-EANFCTGIELLVTGGAELGY 253 A P + M P +++ A FLAS E+ + TG++ V GA L + Sbjct: 240 AFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAMLKF 287 >3RKU-A nrPDB Length = 287 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 51/196 (26%), Positives = 93/196 (47%), Gaps = 10/196 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFV---NSGARVVIC----DKDESGGRALEQELPGAVF 58 R A K V++TG GIG ++ N ++++ +K E + ++QE P A Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 59 ILC--DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 + D+TQ + +K + + F +D +VNNAG R + + + + + + N+ Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 117 GTYTLTKLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 +T+ LP + K+ G+++N+ S+ G Y A+K AV A T +L + Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 176 GVRVNCISPGNIWTPL 191 +RV I+PG + T Sbjct: 210 KIRVILIAPGLVETEF 225 >4EGF-A nrPDB Length = 266 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 81/261 (31%), Positives = 122/261 (46%), Gaps = 25/261 (9%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVF-IL 60 R GK ++TG +GIGA I RAF +GAR+V+ +D ++ RAL ++ V + Sbjct: 17 RLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVA 76 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEETSAQGFRQLLELNLLGTY 119 D+ + D L FG LD +VNNAG HP P +T Q F + +NL Sbjct: 77 IDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPV--VDTDPQLFDATIAVNLRAPA 134 Query: 120 TLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 L + + G +I ++S Y +K + TK LA + P+G+ Sbjct: 135 LLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGI 194 Query: 178 RVNCISPGNIWTPL----WEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLA 232 R N + P + T + W + A P M+A+ PLGR P EV A V+LA Sbjct: 195 RANSVCPTVVLTEMGQRVWGDEAKSAP---------MIARIPLGRFAVPHEVSDAVVWLA 245 Query: 233 SE-ANFCTGIELLVTGGAELG 252 S+ A+ G+++ V GG +G Sbjct: 246 SDAASMINGVDIPVDGGYTMG 266 >2P91-A nrPDB Length = 285 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 60/238 (25%), Positives = 107/238 (44%), Gaps = 20/238 (8%) Query: 9 GKVVVVTG--GGRGIGAGIVRAFVNSGARVVICD---KDESGGRALEQELPGAVFILCDV 63 GK ++TG R I GI ++F GA++ K E R + + + + CDV Sbjct: 21 GKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKCDV 80 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE---ETSAQGFRQLLELNLLGTYT 120 + ++D+K L +G LD +V++ + P + +TS +GF+ +++++ Sbjct: 81 SLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYSLIA 140 Query: 121 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVAT----KGAVTAMTKALALDESPYG 176 LT+ LP + G ++ +S G + VP+ K A+ + + LA D + +G Sbjct: 141 LTRELLPLMEGRNGAIVTLSYY----GAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHG 196 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 R+N IS G + T + T + P G+ +VG AVFL S+ Sbjct: 197 HRINAISAGPVKTLAAYSITGFHLLMEHTTK----VNPFGKPITIEDVGDTAVFLCSD 250 >4RGB-A nrPDB Length = 294 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 76/271 (28%), Positives = 125/271 (46%), Gaps = 31/271 (11%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVV---IC-DKD------------ESGGRALEQE 52 G+VV +TG RG G GA +V IC D D E R +E+ Sbjct: 25 GRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVEKT 84 Query: 53 LPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSA-QGFRQLL 111 +F DV + ++ + + +FG +D V+ NAG P+E A + R L Sbjct: 85 GQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAG--VVLTNPDERDASEALRLGL 142 Query: 112 ELNLLGTYTLTKLALPYL--RKSQGNVINISSLVGAI----GQAQAVPYVATKGAVTAMT 165 ++ L+G + ++A+P++ R GN+I SS++ + G+ Y+ +K A+T + Sbjct: 143 DIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLV 202 Query: 166 KALALDESPYGVRVNCISPGNIWTPLWEELAALMP----DPRATIREGMLAQPLGRMGQP 221 ++ AL + +RVN ++P N TP+ E AL +P + A P M +P Sbjct: 203 RSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPH-LVNAMSTALPDFPMIEP 261 Query: 222 AEVGAAAVFLASEA-NFCTGIELLVTGGAEL 251 +V A +FL S+A TG L V G ++ Sbjct: 262 RDVSNAILFLISDAGRSFTGSVLKVDAGMDV 292 >3OML-A nrPDB Length = 613 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 57/190 (30%), Positives = 90/190 (47%), Gaps = 12/190 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD------KDESGGRA----LEQELPG 55 RY G+V VVTG G G+G F GA+VV+ D D + RA +++ Sbjct: 16 RYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 + D D ++ I+ FGR+D +VNNAG + +TS Q + + +++L Sbjct: 76 GGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAG-ILRDRSLVKTSEQDWNLVNDVHL 134 Query: 116 LGTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 G++ T+ A PY++K G +I SS G G V Y A K + + +A++ + Sbjct: 135 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 175 YGVRVNCISP 184 V N I P Sbjct: 195 NNVLCNVIVP 204 >4HP8-A nrPDB Length = 247 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 114/252 (45%), Gaps = 29/252 (11%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-------GAVFILC 61 G+ +VTG G+G I +GA VV + RA ++ L A +L Sbjct: 9 GRKALVTGANTGLGQAIAVGLAAAGAEVVCAAR-----RAPDETLDIIAKDGGNASALLI 63 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE--ETSAQGFRQLLELNLLGTY 119 D K ++ D +VNNAG +R + E S + +++++NL + Sbjct: 64 DFADPLAAKDSFTDA-----GFDILVNNAG---IIRRADSVEFSELDWDEVMDVNLKALF 115 Query: 120 TLTK-LALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 T+ A L K + G V+NI+SL+ G + Y A K V +TK LA + + G+ Sbjct: 116 FTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGI 175 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236 VN I+PG I T E L A +A + P GR G ++ AAVFL+S A+ Sbjct: 176 NVNAIAPGYIETNNTEALRADAARNKAILER----IPAGRWGHSEDIAGAAVFLSSAAAD 231 Query: 237 FCTGIELLVTGG 248 + G L V GG Sbjct: 232 YVHGAILNVDGG 243 >3OEC-A nrPDB Length = 317 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 73/273 (26%), Positives = 117/273 (42%), Gaps = 31/273 (11%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK-------DESGG---------RA 48 R GKV +TG RG G GA +V D D + G R Sbjct: 42 NRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRL 101 Query: 49 LEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFR 108 +E++ + DV ++ +V E + FG +D +V+N G + T Q + Sbjct: 102 VEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQ-WS 160 Query: 109 QLLELNLLGTYTLTKLALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 +L+ NL+G + + LP + R G+VI +SS VG G Y A+K V + Sbjct: 161 DILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLML 220 Query: 167 ALALDESPYGVRVNCISPGNIWTPL---WEELAALMPDPRATIREGMLAQPLGRMG---- 219 +LA + + +RVN ++PG + T + + L +P RE A+ ++ Sbjct: 221 SLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDA-AELFSQLTLLPI 279 Query: 220 ---QPAEVGAAAVFLAS-EANFCTGIELLVTGG 248 +P +V A +LAS EA + G + V GG Sbjct: 280 PWVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >4DA9-A nrPDB Length = 280 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 76/259 (29%), Positives = 123/259 (47%), Gaps = 16/259 (6%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA-LEQELPG----AVFI 59 T+ A V +VTGG RGIG GI RA SG + I ++ G A + EL G +F+ Sbjct: 25 TQKARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFL 84 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGT 118 D+ + V + FGR+DC+VNNAG + + + F ++ +NL GT Sbjct: 85 RADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGT 144 Query: 119 YTLTKLALPYLRKSQG----NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 T+ L + S ++INI+S+ + + + Y +K + A ++ LAL + Sbjct: 145 VFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAE 204 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-S 233 G+ V + PG I + + AA+ I G++ P+ R G+P ++G LA Sbjct: 205 TGIAVFEVRPGIIRSDMT---AAVSGKYDGLIESGLV--PMRRWGEPEDIGNIVAGLAGG 259 Query: 234 EANFCTGIELLVTGGAELG 252 + F TG + GG +G Sbjct: 260 QFGFATGSVIQADGGLSIG 278 >4TRR-A nrPDB Length = 269 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 58/196 (29%), Positives = 98/196 (50%), Gaps = 15/196 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP----GAVFILCDVT 64 GK VVTG GIG I +GA V I D ++ G A+ E+ A+ + DVT Sbjct: 14 GKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMDVT 73 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRP-EETSAQGFRQLLELNLLGTYTLTK 123 E+ V T + + FG +D +V+NAG P E S ++++ +++ G + TK Sbjct: 74 NEEAVNTGIDKVAEAFGSVDILVSNAG--IQIVNPIENYSFADWKKMQAIHVDGAFLTTK 131 Query: 124 LALPYLRK-SQGNVINISSLVGAIGQAQAVP----YVATKGAVTAMTKALALDESPYGVR 178 AL ++ K +G V+ +G++ +A P YV K + + + LA + + + VR Sbjct: 132 AALKHMYKDDRGGVV---IYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVR 188 Query: 179 VNCISPGNIWTPLWEE 194 + + PG + TPL ++ Sbjct: 189 SHVVCPGFVRTPLVDK 204 >5TF4-A nrPDB Length = 274 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 117/262 (44%), Gaps = 26/262 (9%) Query: 19 RGIGAGIVRAFVNSGARVVICDKDESGGRALE---QELPGAVFILCDVTQEDDVKTLVSE 75 R I GI + ++GA + + E+ + +E +E+ G V CDV+ + + + Sbjct: 24 RSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCGHCDVSDSASIDAVFNT 83 Query: 76 TIRRFGRLDCVVNNAGHHPPPQ---RPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKS 132 +++G+LD +V+ G + R + S F + +++ LTK A L Sbjct: 84 IEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSLTALTKRA-EKLMSD 142 Query: 133 QGNVINISSLVGAIGQAQAVPYV----ATKGAVTAMTKALALDESPYGVRVNCISPGNIW 188 G+++ ++ G + VP K A+ A K LA+D P +RVN IS G Sbjct: 143 GGSILTLTYY----GAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAISAG--- 195 Query: 189 TPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTG 247 P+ A+ + D R ++ PL R EVG +A++L S+ + TG V Sbjct: 196 -PIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSVTGEVHHVDS 254 Query: 248 GAELGYGCKASRSTPVDAPDIP 269 G + G KA VDAPDI Sbjct: 255 GYNI-IGMKA-----VDAPDIS 270 >2X9N-A nrPDB Length = 288 Score = 67.0 bits (162), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 78/277 (28%), Positives = 124/277 (44%), Gaps = 38/277 (13%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDES-GGRALEQELPG-----AV 57 G+ VVTG + IG I +G RVVI + + +L EL AV Sbjct: 18 GSHMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAV 77 Query: 58 FILCDVTQED----DVKTLVSETIRRFGRLDCVVNNA-GHHPPP--QRPEETSAQG---- 106 D+T + + +++ R FGR D +VNNA +P P Q E ++ G Sbjct: 78 VCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVE 137 Query: 107 --FRQLLELNLLGTYTLT-------KLALPYLRKSQGNVINI-SSLVGAIGQAQAVPYVA 156 +L+ N + + LT K P S +++N+ ++V A ++ Y Sbjct: 138 TQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSL-YNM 196 Query: 157 TKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLG 216 K A+ +T++ AL+ +PYG+RVN ++PG P+ A+ + + R + PLG Sbjct: 197 GKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPV-----AMGEEEKDKWRRKV---PLG 248 Query: 217 RMGQPAE-VGAAAVFLAS-EANFCTGIELLVTGGAEL 251 R AE + A +FL S A + TG + V GG L Sbjct: 249 RREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >3OIC-A nrPDB Length = 258 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 117/254 (46%), Gaps = 20/254 (7%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE-----QELPGAVFIL-CD 62 K +VTG RG+G +G +VI + S ALE ++L V ++ + Sbjct: 4 NKCALVTGSSRGVGKAAAIRLAENGYNIVI-NYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNA--GHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 V Q +K + + FGRLD VNNA G P EET + + +N Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETH---WDWTMNINAKALLF 119 Query: 121 LTKLALPYLRKS-QGNVINISSLVGAIGQAQAVPYV-ATKGAVTAMTKALALDESPYGVR 178 + A + K+ G++++ISSL G+I + V +K A+ A+T+ LA++ SP + Sbjct: 120 CAQEAAKLMEKNGGGHIVSISSL-GSIRYLENYTTVGVSKAALEALTRYLAVELSPKQII 178 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFL-ASEANF 237 VN +S G I T + P+ + + P GRM + ++ FL +S+A+ Sbjct: 179 VNAVSGGAIDTDALKHF----PNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADM 234 Query: 238 CTGIELLVTGGAEL 251 G ++V GG L Sbjct: 235 IRGQTIIVDGGRSL 248 >3V8B-A nrPDB Length = 283 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 115/252 (45%), Gaps = 11/252 (4%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA----VFILCDVTQE 66 V ++TG G GIG A G V + + + E+ GA + + DV+ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 ++ V + + +FG LD VV NAG + ++ + + + +NL GT+ L + Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTV 149 Query: 127 PYLRKSQGN-VINISSLVGA--IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 PYL++ G ++ +SS+ G A Y ATK A A+ + LAL+ + +RVN + Sbjct: 150 PYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNAVC 209 Query: 184 PGNIWTPLWEELAALMPDPRATIRE---GMLAQPLGRMGQPAEVGAAAVFLASE-ANFCT 239 PG I T + + + A E G + G+ G+ +V FL SE A T Sbjct: 210 PGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARHVT 269 Query: 240 GIELLVTGGAEL 251 G + + GG L Sbjct: 270 GSPVWIDGGQGL 281 >5ILO-A nrPDB Length = 271 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 30/218 (13%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSG-ARVVICDKDESGGRALEQELP-------- 54 GT + GK VVTGG GIG + + + +G A+V I D ++ LE+ + Sbjct: 10 GTSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDN----LEEFVKLRAAHPTQ 65 Query: 55 GAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELN 114 + I DV + V+ E + FG +D VVN AG + + ++ L +N Sbjct: 66 SVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIF---------NDKDVQRTLLVN 116 Query: 115 LLGTYTLTKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALAL 170 L G T ALPY+ K G V+N+SS+VG Y ATK + T+ LA Sbjct: 117 LGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLA- 175 Query: 171 DESPY---GVRVNCISPGNIWTPLWEELAALMPDPRAT 205 +E Y G++ + PG T ++ + P + Sbjct: 176 NEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETS 213 >5PGZ-A nrPDB Length = 276 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 6/158 (3%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-----GRALEQELPGAVFILCDV 63 GK V+VTG +GIG + GA VV+ + E G R LE A +I + Sbjct: 18 GKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTM 77 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + + + + G LD ++ N + R+++E+N L ++ Sbjct: 78 EDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHD-DIHSVRRVMEVNFLSYVVMST 136 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAV 161 ALP L++S G++ ISSL G + Q PY A+K A+ Sbjct: 137 AALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFAL 174 >5YCX-A nrPDB Length = 266 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 80/259 (30%), Positives = 120/259 (46%), Gaps = 26/259 (10%) Query: 9 GKVVVVTG--GGRGIGAGIVRAFVNSGARVVIC---DKDESGGRALEQELPG--AVFILC 61 GK VV G R I GI R+ N+GA+++ ++ E R L L G ++ + C Sbjct: 8 GKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVLPC 67 Query: 62 DVTQEDDVKTLVSETIRR-----FGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 DVT ++++ T ETI++ G C+ A +TS GF LL N+ Sbjct: 68 DVTNDEEL-TACFETIKQEVGTIHGVAHCIAF-ANRDDLKGEFVDTSRDGF--LLAQNI- 122 Query: 117 GTYTLTKLA--LPYLRKSQGNVINISSLVGA-IGQAQAVPYVATKGAVTAMTKALALDES 173 ++LT +A + GN++ ++ L G + + V VA K ++ A K LA D Sbjct: 123 SAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVA-KASLEASVKYLANDLG 181 Query: 174 PYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 +G+RVN IS G P+ A + D + +RE PL R EVG AVFL S Sbjct: 182 QHGIRVNAISAG----PIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFS 237 Query: 234 E-ANFCTGIELLVTGGAEL 251 + A TG + V G + Sbjct: 238 DLARGVTGENIHVDSGYHI 256 >2PD3-A nrPDB Length = 275 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 56/227 (24%), Positives = 98/227 (43%), Gaps = 13/227 (5%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG---RALEQELPGAVFILCDVTQED 67 ++V + I GI ++ N GA + +ES R + QEL DV++E+ Sbjct: 10 LIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVYELDVSKEE 69 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE----ETSAQGFRQLLELNLLGTYTLTK 123 K+L + + G LD +V++ P + E ETS F +E+++ LT Sbjct: 70 HFKSLYNSVKKDLGSLDFIVHSVA-FAPKEALEGSLLETSKSAFNTAMEISVYSLIELTN 128 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 P L +V+ +S L A K A+ + + LA+D + +RVN +S Sbjct: 129 TLKPLLNNG-ASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIRVNALS 187 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVF 230 G P+ ++ + D R ++ + PL + EVG A ++ Sbjct: 188 AG----PIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMY 230 >3U4C-A nrPDB Length = 281 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 56/264 (21%), Positives = 115/264 (43%), Gaps = 24/264 (9%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-----PGAVF 58 G+ + + V G +GIG I + +VI ++ ++++++ +V Sbjct: 18 GSHMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVI 77 Query: 59 ILC-DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHP--PPQRPEETSAQGFRQLLELNL 115 +L D++ + + + + GRLD ++NN P P + + + Sbjct: 78 VLAGDMSDQHTRAGIFQKIESQCGRLDVLINNI---PGGAPDTFDNCNIEDMTATFTQKT 134 Query: 116 LGTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQ---AQAVPYVATKGAVTAMTKALALD 171 + K A +++++ G +INI VG + + A A+ +K +++ Sbjct: 135 VAYIDAIKRASSLMKQNEFGRIINI---VGNLWKEPGANMFTNSMMNAALINASKNISIQ 191 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-----PLGRMGQPAEVGA 226 +P+ + VNC++PG I T + + + + ++ Q P+ R+G E A Sbjct: 192 LAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAA 251 Query: 227 AAVFLAS-EANFCTGIELLVTGGA 249 A FLAS EA++ TG ++ GG+ Sbjct: 252 LAAFLASEEASYITGQQISADGGS 275 >3GRK-A nrPDB Length = 293 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 71/268 (26%), Positives = 115/268 (42%), Gaps = 40/268 (14%) Query: 19 RGIGAGIVRAFVNSGARVVICDKDESGGRALE---QELPGAVFILCDVTQEDDVKTLVSE 75 R I GI +A +GA + + ++ + +E +EL V CDV + + Sbjct: 43 RSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAGHCDVADAASIDAVFET 102 Query: 76 TIRRFGRLDCVVNNAGHHPPPQ---RPEETSAQGFRQLLELNLLGTYTLTKLA--LPYLR 130 +++G+LD +V+ G + R +TS F + L+ Y+LT ++ L Sbjct: 103 LEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTM---LISVYSLTAVSRRAEKLM 159 Query: 131 KSQGNVINISSLVGAIGQAQAVPYV----ATKGAVTAMTKALALDESPYGVRVNCISPGN 186 G+++ ++ G + +P K A+ A K LA+D P +RVN IS G Sbjct: 160 ADGGSILTLTYY----GAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIRVNAISAG- 214 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVT 246 P+ A+ + D R ++ PL R EVG ++ F + + VT Sbjct: 215 ---PIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLY------FLSDLSRSVT 265 Query: 247 G---GAELGY---GCKASRSTPVDAPDI 268 G A+ GY G KA VDAPDI Sbjct: 266 GEVHHADSGYHVIGMKA-----VDAPDI 288 >5KOI-A nrPDB Length = 293 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 58/224 (25%), Positives = 101/224 (45%), Gaps = 24/224 (10%) Query: 24 GIVRAFVNSGARVVICDKDESGGRALE--QELPGAVFIL-CDVTQEDDVKTLVSETIRRF 80 GI + GA + + ++ G+ ++ E G+ F+L CDV V + E +++ Sbjct: 45 GIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVLPCDVEDIATVDAVFEEIEKKW 104 Query: 81 GRLDCVVNNAGHHPPPQ----RPEETSAQGFRQLLELNLLGTYTLTKLA--LPYLRKSQG 134 G LD +V+ G + + T+ + F + + ++ Y+ T++A L K G Sbjct: 105 GGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTM---VISAYSFTEVAQRAEKLMKDGG 161 Query: 135 NVINISSLVGAIGQAQAVPYV----ATKGAVTAMTKALALDESPYGVRVNCISPGNIWTP 190 +++ ++ G + +P K A+ AM + LA D P G+RVN IS G P Sbjct: 162 SILTLTYG----GSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAG----P 213 Query: 191 LWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 + A + D RA PL R +VG +AV+L S+ Sbjct: 214 VRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSD 257 >4M89-A nrPDB Length = 261 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 62/239 (25%), Positives = 98/239 (41%), Gaps = 21/239 (8%) Query: 9 GKVVVVTG--GGRGIGAGIVRAFVNSGARVV---ICDKDESGGRALEQELPGAVFILCDV 63 GK +++TG R I GI +A GA + + DK E R + EL + CDV Sbjct: 6 GKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVFRCDV 65 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRP----EETSAQGFRQLLELNLLGTY 119 +D++ + ++ + + LD +V++ G P + S + F E++ Sbjct: 66 ASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAYSLP 125 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA----LALDESPY 175 L K A P +R ++ +S L G +A+P G A +A A Sbjct: 126 ALAKAARPMMRGRNSAIVALSYL----GAVRAIPNYNVMGMAKASLEAGIRFTAACLGKE 181 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 G+R N IS G P+ A+ + D + PL R EVG A FL S+ Sbjct: 182 GIRCNGISAG----PIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSD 236 >3UCF-A nrPDB Length = 223 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 68/245 (27%), Positives = 108/245 (44%), Gaps = 32/245 (13%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 V VV GG GIGA + + + S +V ++G D++ E V Sbjct: 8 VYVVLGGTSGIGAELAKQ-LESEHTIVHVASRQTG---------------LDISDEKSVY 51 Query: 71 TLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLR 130 ETI G D ++ AG + P + + + + G K YL+ Sbjct: 52 HYF-ETI---GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGARYLK 107 Query: 131 KSQGNVINISSLVGAIG-QAQAVPYV--ATKGAVTAMTKALALDESPYGVRVNCISPGNI 187 QG I ++S G + + A YV A A+ A TK LA + +P +RVN ISPG Sbjct: 108 --QGGSITLTS--GMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAISPGLT 161 Query: 188 WTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTG 247 T ++ + A D A + P+G++G+ +++ A +F A + ++ TG + V G Sbjct: 162 KTEAYKGMNA--DDRDAMYQRTQSHLPVGKVGEASDIAMAYLF-AIQNSYMTGTVIDVDG 218 Query: 248 GAELG 252 GA LG Sbjct: 219 GALLG 223 >3K2E-A nrPDB Length = 296 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 72/280 (25%), Positives = 115/280 (41%), Gaps = 26/280 (9%) Query: 1 MATGTRYAGK--VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA---LEQELPG 55 M TG GK V++ + + GI +A GA V + E+ + L + L Sbjct: 22 MRTGMLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGV 81 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQ---RPEETSAQGFRQLLE 112 + + CDV+ + V + +G LD VV+ + R +TS F + Sbjct: 82 KLTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMH 141 Query: 113 LNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYV----ATKGAVTAMTKAL 168 ++ + A P L + G+++ +S G + VP+ K A+ A K L Sbjct: 142 ISCYSFTYIASKAEP-LMTNGGSILTLSYY----GAEKVVPHYNVMGVCKAALEASVKYL 196 Query: 169 ALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAA 228 A+D +RVN IS G P+ ++ + D + PL R +VG AA Sbjct: 197 AVDLGKQQIRVNAISAG----PVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAA 252 Query: 229 VFLASEANFCTGIELLVTGGAELGYGCKASRSTPVDAPDI 268 ++L S+ T E T + GY +S VDAPDI Sbjct: 253 LYLLSDLGRGTTGE---TVHVDCGYHVVGMKS--VDAPDI 287 >1SNY-A nrPDB Length = 267 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 63/239 (26%), Positives = 108/239 (45%), Gaps = 31/239 (12%) Query: 12 VVVTGGGRGIGAGIVRAFVN---SGARVVICDKDESGGRALEQ--ELPGAVFIL-CDVTQ 65 +++TG RG+G G+V+A +N + ++ + LE + + IL D+ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRN 83 Query: 66 EDDVKTLVS--ETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 D LV+ E + + L+ + NNAG P R +Q L+ N + L K Sbjct: 84 FDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAK 143 Query: 124 LALPYLRKS------------QGNVINISSLVGAI---GQAQAVPYVATKGAVTAMTKAL 168 LP L+K+ + +IN+SS++G+I Y +K A+ A TK+L Sbjct: 144 ACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSL 203 Query: 169 ALDESPYGVRVNCIS--PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVG 225 ++D P R+ C+S PG + T + A L P +T G + Q + ++G+ G Sbjct: 204 SVDLYPQ--RIMCVSLHPGWVKTDMGGSSAPL-DVPTST---GQIVQTISKLGEKQNGG 256 >3DWF-A nrPDB Length = 276 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 71/167 (42%), Gaps = 10/167 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-----GRALEQELPGAVFILCDV 63 GK V+VTG +GIG I GA VV+ + + R LE A +I + Sbjct: 11 GKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSM 70 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQ--GFRQLLELNLLGTYTL 121 + V+E G LD ++ N H R + R+ +E+N L Sbjct: 71 EDMTFAEEFVAEAGNLMGGLDMLILN---HVLYNRLTFFHGEIDNVRKSMEVNFHSFVVL 127 Query: 122 TKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKAL 168 + A+P L +SQG++ +SS+ G I PY A+K A+ L Sbjct: 128 SVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTL 174 >1FJH-A nrPDB Length = 257 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 64/269 (23%), Positives = 114/269 (42%), Gaps = 55/269 (20%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 ++V++G GIGA + +G ++V D ++ ++ D++ + K Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE-------------VIADLSTAEGRK 49 Query: 71 TLVSETIRRFGR-LDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 +++ + + + +D +V AG P +T G ++ +N G L LP L Sbjct: 50 QAIADVLAKCSKGMDGLVLCAGLGP------QTKVLG--NVVSVNYFGATELMDAFLPAL 101 Query: 130 RK-SQGNVINISSLV-----------------GAIGQAQAV-----------PYVATKGA 160 +K Q + ISS+ G +A+A+ Y +K A Sbjct: 102 KKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNA 161 Query: 161 VTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQ 220 +T + A GVR+N I+PG TPL L A + DPR P+GR + Sbjct: 162 LTVAVRKRAAAWGEAGVRLNTIAPGATETPL---LQAGLQDPRYGESIAKFVPPMGRRAE 218 Query: 221 PAEVGAAAVFLAS-EANFCTGIELLVTGG 248 P+E+ + FL S A++ G ++++ GG Sbjct: 219 PSEMASVIAFLMSPAASYVHGAQIVIDGG 247 >2YW9-A nrPDB Length = 261 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 98/236 (41%), Gaps = 17/236 (7%) Query: 8 AGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDES---GGRALEQELPGAVFILCD 62 +GK +V G R +G I +GA V + + E L + L GA+ D Sbjct: 7 SGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLFRAD 66 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQ---RPEETSAQGFRQLLELNLLGTY 119 VTQ++++ L + FG LD +V+ P R +T Q + LE++ Sbjct: 67 VTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYSLV 126 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + + A P LR+ G ++ ++ + K A+ A + LA + P GVRV Sbjct: 127 AVARRAEPLLREG-GGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVRV 185 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQ--PLGRMGQPAEVGAAAVFLAS 233 N IS G + T A P T +AQ PL R EVG +FL S Sbjct: 186 NAISAGPVRT------VAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLS 235 >3U9L-A nrPDB Length = 324 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 18/190 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDV---TQE 66 K++++TG G G A +G RV +D G A E DV T E Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLE 65 Query: 67 DDVKTLVS------ETIRRFGRLDCVVNNAGHH---PPPQRPEETSAQGFRQLLELNLLG 117 DV++ VS + I GR+D +++NAGH P E + + F +L ++N+L Sbjct: 66 LDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPA----EAFTPEQFAELYDINVLS 121 Query: 118 TYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAV-PYVATKGAVTAMTKALALDESPY 175 T + + ALP++R+ + G +I ISS A G + PY A K A+ A+ A + S + Sbjct: 122 TQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRW 181 Query: 176 GVRVNCISPG 185 G+ + I PG Sbjct: 182 GIETSIIVPG 191 >2DKN-A nrPDB Length = 255 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 4/100 (4%) Query: 152 VPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGML 211 + Y +K AVT + + +D + GVR+N ++PG + TPL L A DPR Sbjct: 151 LAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPL---LQASKADPRYGESTRRF 207 Query: 212 AQPLGRMGQPAEVGAAAVF-LASEANFCTGIELLVTGGAE 250 PLGR +P EV A F L +A+F G L V GG + Sbjct: 208 VAPLGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGMD 247 >3O26-A nrPDB Length = 311 Score = 53.5 bits (127), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 51/207 (24%), Positives = 90/207 (43%), Gaps = 42/207 (20%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA-----VFILCDVT 64 + VVTGG +GIG I + ++G VV+ +D + G ++L + VF DVT Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 65 QEDDVKTLVSETIR-RFGRLDCVVNNAG-----------------------------HHP 94 + +++ I+ FG+LD +VNNAG P Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYEKP 132 Query: 95 PPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG-NVINISSLVGAIGQAQAVP 153 Q + + + L++N G ++T++ +P L+ S ++N+SS G++ Sbjct: 133 EAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSL------K 186 Query: 154 YVATKGAVTAMTKALALDESPYGVRVN 180 YV+ + A+ + AL E + VN Sbjct: 187 YVSNETALEILGDGDALTEERIDMVVN 213 >2NWQ-A nrPDB Length = 272 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 5/184 (2%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL---CDV 63 + + +TG G G R F +G +V+ + E +AL EL +L DV Sbjct: 19 HMSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDV 78 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + V F L ++NNAG + + +++ N+ G T+ Sbjct: 79 RDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTR 138 Query: 124 LALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 L LP L + +++N+ S+ G + Y TK V + L D GVRV Sbjct: 139 LLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTN 198 Query: 182 ISPG 185 + PG Sbjct: 199 LEPG 202 >3BHI-A nrPDB Length = 276 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 7/161 (4%) Query: 11 VVVVTGGGRGIGAGIVRAFVN-SGARVVICDKDESGGRALEQELPGA----VFILCDVTQ 65 V +VTGG +GIG IVR VV+ +D + G+A Q+L F D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 ++ L + +G LD +VNNAG P Q ++ N GT + Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTEL 124 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 LP + K QG V+N+SS++ P + K +T+ Sbjct: 125 LPLI-KPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITE 164 >4JQC-A nrPDB Length = 282 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/243 (24%), Positives = 109/243 (44%), Gaps = 28/243 (11%) Query: 8 AGKVVVVTG--GGRGIGAGIVRAFVNSGARVVIC-DKDESGGRALE--QELPGAVFILCD 62 +GK ++VTG I GI +A GA + D+ GR E +L + + CD Sbjct: 25 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 84 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNLLGT 118 V ++ + T+ +E + + + D V++ G P Q + + +GF+ +++ + Sbjct: 85 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS---S 141 Query: 119 YTLTKLALPYLRKSQGNVINISS---LVGAIGQAQAVPYVAT----KGAVTAMTKALALD 171 Y+ +A K+ +++N S + +G +A+P K ++ A + +A Sbjct: 142 YSFVAMA-----KACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 196 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFL 231 P GVRVN IS G P+ A+ + D R + P+ R +VG +A FL Sbjct: 197 MGPEGVRVNAISAG----PIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 252 Query: 232 ASE 234 S+ Sbjct: 253 CSD 255 >1N5D-A nrPDB Length = 288 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 7/162 (4%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGA-RVVICDKDESGGRALEQELPGA----VFILCDVT 64 +V +VTG +GIG IVR A VV+ +D + G+A ++L F D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 ++ L + +G LD +VNNA P Q ++ N +GT + Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQA-ELTMKTNFMGTRNVCTE 123 Query: 125 ALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 LP + K QG V+N+SS G + P + K +T+ Sbjct: 124 LLPLI-KPQGRVVNVSSTEGVRALNECSPELQQKFKSETITE 164 >4ALL-A nrPDB Length = 277 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 99/237 (41%), Gaps = 19/237 (8%) Query: 10 KVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-----PGAVFILCD 62 K V+ G R I G+ + GA++V + E + LE+ L P A D Sbjct: 28 KTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQID 87 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNN---AGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 V +++V + + G +D V ++ A R ETS +GF LL ++ +Y Sbjct: 88 VQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGF--LLAQDI-SSY 144 Query: 120 TLTKLAL--PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 +LT +A L G+++ + L G K ++ A K LALD P + Sbjct: 145 SLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNI 204 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 RVN IS G I T + + ++E PL R EVG A +L S+ Sbjct: 205 RVNAISAGPIRTLSAKGVGGF----NTILKEIEERAPLKRNVDQVEVGKTAAYLLSD 257 >5CFZ-A nrPDB Length = 305 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/243 (24%), Positives = 109/243 (44%), Gaps = 28/243 (11%) Query: 8 AGKVVVVTG--GGRGIGAGIVRAFVNSGARVVIC-DKDESGGRALE--QELPGAVFILCD 62 +GK ++VTG I GI +A GA + D+ GR E +L + + CD Sbjct: 48 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 107 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNLLGT 118 V ++ + T+ +E + + + D V++ G P Q + + +GF+ +++ + Sbjct: 108 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS---S 164 Query: 119 YTLTKLALPYLRKSQGNVINISS---LVGAIGQAQAVPYVAT----KGAVTAMTKALALD 171 Y+ +A K+ +++N S + +G +A+P K ++ A + +A Sbjct: 165 YSFVAMA-----KACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 219 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFL 231 P GVRVN IS G P+ A+ + D R + P+ R +VG +A FL Sbjct: 220 MGPEGVRVNAISAG----PIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 275 Query: 232 ASE 234 S+ Sbjct: 276 CSD 278 >5TQV-A nrPDB Length = 233 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 92/206 (44%), Gaps = 14/206 (6%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 MA + K V++ G RG+G VR + G V+ +D++ AL GA Sbjct: 1 MAHHHHHHMKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRA--LGAHAHA 58 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET-SAQGFRQLLELNLLGTY 119 D+TQ + + L + RLD V +G + P ET ++ F ++ N+ G Sbjct: 59 LDITQPEQIAALGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPM 116 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP---YVATKGAVTAMTKALALDESPYG 176 L + LP + ++G + +SS +G+I +A Y A+K A+ + + +L Sbjct: 117 QLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIASLQTR--- 173 Query: 177 VRVNCIS--PGNIWTPLWEELAALMP 200 CIS PG + T + AAL P Sbjct: 174 -HAACISLHPGWVRTDMGGAQAALDP 198 >3E9N-A nrPDB Length = 245 Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 13/208 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 K+ VVTG G+G IV+ S +V A E+ G I D+ +E Sbjct: 6 KIAVVTGATGGMGIEIVKDL--SRDHIVYALGRNPEHLAALAEIEGVEPIESDIVKE--- 60 Query: 70 KTLVSETIRRFGRLDCVVNNAGHHPPPQRP---EETSAQGFRQLLELNLLGTYTLTKLAL 126 L + + LD V + H R E S + L+LN++ L++ L Sbjct: 61 -VLEEGGVDKLKNLDHV-DTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLL 118 Query: 127 PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186 P LR + G VI I+S G Y A+K A+ + A +E+ G+RV+ +SPG Sbjct: 119 PALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGP 178 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQP 214 TP+ L LM R + +P Sbjct: 179 TNTPM---LQGLMDSQGTNFRPEIYIEP 203 >2BFA-A nrPDB Length = 288 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 59/203 (29%), Positives = 93/203 (45%), Gaps = 32/203 (15%) Query: 72 LVSETIRRFGRLDCVVNNAG-HHPPPQ-RPEETSAQ---GFRQLLEL--------NLLGT 118 LV+ +GR D +VNNA +P P R +E + G R+ +E N + Sbjct: 92 LVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAP 151 Query: 119 YTLTKLALPYLR----KSQGNVINISSLVGAIGQAQAV---PYVATKGAVTAMTKALALD 171 Y L K + K +G +I ++V A+ + Y KGA+ +T++ AL+ Sbjct: 152 YFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALE 211 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PL-GRMGQPAEVGAAAV 229 +P +RVN + PG L+ L+ D + EG ++ PL R AEV + Sbjct: 212 LAPLQIRVNGVGPG---------LSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVI 262 Query: 230 FL-ASEANFCTGIELLVTGGAEL 251 FL +S+A + TG + V GG L Sbjct: 263 FLCSSKAKYITGTCVKVDGGYSL 285 >2QHX-A nrPDB Length = 328 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 59/203 (29%), Positives = 93/203 (45%), Gaps = 32/203 (15%) Query: 72 LVSETIRRFGRLDCVVNNAG-HHPPPQ-RPEETSAQ---GFRQLLEL--------NLLGT 118 LV+ +GR D +VNNA +P P R +E + G R+ +E N + Sbjct: 132 LVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAP 191 Query: 119 YTLTKLALPYLR----KSQGNVINISSLVGAIGQAQAV---PYVATKGAVTAMTKALALD 171 Y L K + K +G +I ++V A+ + Y KGA+ +T++ AL+ Sbjct: 192 YFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALE 251 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PL-GRMGQPAEVGAAAV 229 +P +RVN + PG L+ L+ D + EG ++ PL R AEV + Sbjct: 252 LAPLQIRVNGVGPG---------LSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVI 302 Query: 230 FL-ASEANFCTGIELLVTGGAEL 251 FL +S+A + TG + V GG L Sbjct: 303 FLCSSKAKYITGTCVKVDGGYSL 325 >5L51-A nrPDB Length = 324 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 49/189 (25%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG----RALEQELPGAV 57 A RYA VVTG +GIG I + + G V++ +DE G L +EL G+ Sbjct: 12 AATKRYA----VVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKEL-GSE 66 Query: 58 FILCDVTQEDD------VKTLVSETIRRFGRLDCVVNNAG-------------------- 91 F V+Q+ D V LV +FG LD +VNNAG Sbjct: 67 FGDYVVSQQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAE 126 Query: 92 -------------HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG-NVI 137 +HP + + ++ +E N G+ +T+ +P L++S ++ Sbjct: 127 FKTFQSGAAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIV 186 Query: 138 NISSLVGAI 146 N+SS + ++ Sbjct: 187 NVSSTLSSL 195 >5LCX-A nrPDB Length = 316 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 12/99 (12%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA---- 56 MA RYA +VTG +GIG I R G V++ ++E G Q+L Sbjct: 3 MAEVQRYA----LVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVS 58 Query: 57 ----VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG 91 VF DVT V + +FG+LD +VNNAG Sbjct: 59 ENRLVFHQLDVTDLASVAAVAVFIKSKFGKLDILVNNAG 97 >2HRB-A nrPDB Length = 274 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 40/139 (28%), Positives = 59/139 (42%), Gaps = 7/139 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNS-GARVVICDKDESGGRALEQELPGA----VFILCDV 63 +V +VTG RGIG I R VV+ +D + G+A Q+L F D+ Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDI 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 ++ L + +G L+ +VNNA P + L+ N T + Sbjct: 62 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKA-EMTLKTNFFATRNMCN 120 Query: 124 LALPYLRKSQGNVINISSL 142 LP + K G V+NISSL Sbjct: 121 ELLPIM-KPHGRVVNISSL 138 >4HBG-A nrPDB Length = 286 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 18/100 (18%) Query: 102 TSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG------------NVINISSLVGAIGQA 149 T+A + ++ +N + T+T + + Y+ KSQ ++NISS++ + G+ Sbjct: 132 TTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS-GKM 190 Query: 150 QAVP----YVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + VP Y A+K A++ T+ LA + P +R ISPG Sbjct: 191 K-VPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 >5WQO-A nrPDB Length = 234 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 92/193 (47%), Gaps = 21/193 (10%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE--QELPGAVF--ILCDVTQED 67 V++ G RGIG G+ AF+ GA+V + G L+ E G + D+ Q D Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRP-EETSAQGFRQLLELNLLGTYTLTKLAL 126 + + R R+D ++ NAG + P Q+ E A+ QL N + L + AL Sbjct: 69 CAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLAR-AL 125 Query: 127 PYLRKSQGNVI-----NISSLVGAIGQAQAVP-YVATKGAVTAMTKAL--ALDESPYGVR 178 R S+G V+ ++SL A+G + +P Y A+K A+ ++ ++ +E P+ + Sbjct: 126 SG-RVSRGGVVAFMSSQMASL--ALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLL 182 Query: 179 VNCISPGNIWTPL 191 + + PG + T + Sbjct: 183 L--LHPGWVRTEM 193 >4Q9N-A nrPDB Length = 298 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 21/193 (10%) Query: 69 VKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKLALP 127 V +V + + FG +D +V++ + P +P +TS +G+ L + +Y+ L Sbjct: 106 VSEVVEQVKKHFGHIDILVHSLANSPEIAKPLLDTSRKGYLAALSTS---SYSFISLLSH 162 Query: 128 Y--LRKSQGNVINISSLVGAIGQAQAVP-----YVATKGAVTAMTKALALDESP-YGVRV 179 + + + + I+++ L +AVP A K A+ + TK LA + +GVRV Sbjct: 163 FGPIMNAGASTISLTYL----ASMRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRV 218 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238 N IS G PL + + PL + +VGAAA FL S A+ Sbjct: 219 NTISAG----PLASRAGKAIGFIERMVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAI 274 Query: 239 TGIELLVTGGAEL 251 TG L V GA + Sbjct: 275 TGETLYVDHGANV 287 >1P33-A nrPDB Length = 289 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 56/212 (26%), Positives = 90/212 (42%), Gaps = 32/212 (15%) Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEET----SAQGFRQLLEL---- 113 VT LV +GR D +VNNA +P P ++ S+ G ++ LE+ Sbjct: 84 VTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGGSSVGDKESLEVAAAD 143 Query: 114 ----NLLGTYTLTKLALPYLRKSQGNVINIS-SLVGAIGQAQAVP------YVATKGAVT 162 N + Y L K + ++ S S+V + + P Y K A+ Sbjct: 144 LFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQPLLGYTMYTMAKEALE 203 Query: 163 AMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQP 221 +T++ AL+ + +RVN +SPG L+ L D +++E + PL + Sbjct: 204 GLTRSAALELASLQIRVNGVSPG---------LSVLPDDMPFSVQEDYRRKVPLYQRNSS 254 Query: 222 A-EVGAAAVFLAS-EANFCTGIELLVTGGAEL 251 A EV +FL S +A + TG + V GG L Sbjct: 255 AEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >1B15-A nrPDB Length = 254 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 55/218 (25%), Positives = 87/218 (39%), Gaps = 24/218 (11%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGG-----RALEQELPGAVFILCD 62 K V+ GIG R V + VI D+ E+ +A+ ++ F D Sbjct: 5 NKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKV-NITFHTYD 63 Query: 63 VTQE-DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 VT + K L+ + + +D ++N AG Q + + +N G Sbjct: 64 VTVPVAESKKLLKKIFDQLKTVDILINGAGILDDHQ---------IERTIAINFTGLVNT 114 Query: 122 TKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 T L + K +G + NI S+ G Q Y A+K AV + T +LA GV Sbjct: 115 TTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGV 174 Query: 178 RVNCISPGNIWTPLWEELAALMP-DPRATIREGMLAQP 214 I+PG TPL + + +PR + E +L+ P Sbjct: 175 TAYSINPGITRTPLVHTFNSWLDVEPR--VAELLLSHP 210 >2O2S-A nrPDB Length = 315 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 55/210 (26%), Positives = 86/210 (40%), Gaps = 27/210 (12%) Query: 69 VKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKLALP 127 +K + + + G +D +V++ + P +P ETS +G+ L + Y+ L Sbjct: 107 IKEVAVKVKQDLGNIDILVHSLANGPEVTKPLLETSRKGY---LAASSNSAYSFVSLLQH 163 Query: 128 Y--LRKSQGNVINISSLVGAIGQAQAVP-----YVATKGAVTAMTKALALDE-SPYGVRV 179 + + G+ + +S L + VP + K A+ + T+ LA + YGVRV Sbjct: 164 FGPIMNEGGSAVTLSYLAAE----RVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRV 219 Query: 180 NCISPGNIWTPLWEELAALMPDP------RATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 N IS G PL A+ + I PL R +VG AA+FL S Sbjct: 220 NAISAG----PLKSRAASAIGKSGEKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLS 275 Query: 234 E-ANFCTGIELLVTGGAELGYGCKASRSTP 262 A +G+ L V G SRS P Sbjct: 276 PLARAVSGVTLYVDNGLHAMGQAVDSRSMP 305 >1BXK-A nrPDB Length = 355 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 34/182 (18%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALE----QELPGAVFILCDVT 64 + +++TGG IG+ +VR +N + VV+ DK G + + F D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 ++ + +E + DCV+ H + + S G +E N++GTYTL + Sbjct: 62 DRAELARVFTE-----HQPDCVM-----HLAAESHVDRSIDGPAAFIETNIVGTYTLLEA 111 Query: 125 ALPYL------RKSQGNVINISS-------------LVGAIGQAQAVPYVATKGAVTAMT 165 A Y +KS +IS+ A + PY A+K + + Sbjct: 112 ARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLV 171 Query: 166 KA 167 +A Sbjct: 172 RA 173 >5Y28-A nrPDB Length = 357 Score = 34.7 bits (78), Expect = 0.048, Method: Compositional matrix adjust. Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 14/140 (10%) Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA-LALDESP 174 L +TK LP ++ S N I++ LV AIG V T+G V+A+ K+ + ++ Sbjct: 138 LAVIRITKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQGIVSALNKSGIGINSYE 197 Query: 175 YGVRVN-CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 ++ + I+PGN L + L+ G+ + + G +G A + S Sbjct: 198 NFIQTDASINPGNSGGALIDSRGGLV---------GINTAIISKTGGNHGIGFA---IPS 245 Query: 234 EANFCTGIELLVTGGAELGY 253 T +L+ TG E GY Sbjct: 246 NMVKDTVTQLIKTGKIERGY 265 >3ORF-A nrPDB Length = 251 Score = 34.7 bits (78), Expect = 0.048, Method: Compositional matrix adjust. Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 15/166 (9%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA--VFILCDVT 64 + K ++V GG +GA +V+ F + + D +E P A F + D + Sbjct: 20 HMSKNILVLGGSGALGAEVVKFFKSKSWNTISID---------FRENPNADHSFTIKD-S 69 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 E+++K+++ + + ++D V AG + + + ++++NL + + Sbjct: 70 GEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHI 129 Query: 125 ALPYLRKSQGNVINISSLVGAIGQAQA-VPYVATKGAVTAMTKALA 169 L +QG + ++ A+ + + Y ATK A + K LA Sbjct: 130 GAKLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLA 173 >5Y2D-A nrPDB Length = 465 Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust. Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 14/140 (10%) Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA-LALDESP 174 L +TK LP ++ S N I++ LV AIG V T+G V+A+ K+ + ++ Sbjct: 138 LAVIRITKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQGIVSALNKSGIGINSYE 197 Query: 175 YGVRVN-CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 ++ + I+PGN L + L+ G+ + + G +G A + S Sbjct: 198 NFIQTDASINPGNSGGALIDSRGGLV---------GINTAIISKTGGNHGIGFA---IPS 245 Query: 234 EANFCTGIELLVTGGAELGY 253 T +L+ TG E GY Sbjct: 246 NMVKDTVTQLIKTGKIERGY 265 >3OND-A nrPDB Length = 488 Score = 33.9 bits (76), Expect = 0.075, Method: Compositional matrix adjust. Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFIL 60 AT AGKV VV G G +G G A +GARV++ + D AL+ + G V L Sbjct: 258 ATDVMIAGKVAVVAGYG-DVGKGCAAALKQAGARVIVTEIDPIC--ALQATMEGLQVLTL 314 Query: 61 CDVTQEDD--VKTLVSETIRRFGRLDCVVNNA 90 DV E D V T ++ I + + NNA Sbjct: 315 EDVVSEADIFVTTTGNKDIIMLDHMKKMKNNA 346 >3NJ4-A nrPDB Length = 435 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 11/99 (11%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFIL 60 AT AGKV VV G G +G G +A GARV+I + D AL+ + G V + Sbjct: 209 ATDVMIAGKVAVVAGYG-DVGKGCAQALRGFGARVIITEIDPIN--ALQAAMEGYEVTTM 265 Query: 61 CDVTQEDDVKTLVSETI-----RRFGRL--DCVVNNAGH 92 + QE ++ + I R F ++ D +V N GH Sbjct: 266 DEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGH 304 >3H9U-A nrPDB Length = 436 Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust. Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 17/102 (16%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFIL 60 AT AGK V G G +G G A GARVV+ + D AL+ + G V ++ Sbjct: 204 ATDVMIAGKTACVCGYG-DVGKGCAAALRGFGARVVVTEVDPIN--ALQAAMEGYQVLLV 260 Query: 61 CDVTQE----------DDVKTLVSETIRRFGRLDCVVNNAGH 92 DV +E DD+ + SE R R D +V N GH Sbjct: 261 EDVVEEAHIFVTTTGNDDI--ITSEHFPRM-RDDAIVCNIGH 299 >2PTG-A nrPDB Length = 319 Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust. Identities = 54/206 (26%), Positives = 88/206 (42%), Gaps = 25/206 (12%) Query: 73 VSETIR-RFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKLALPYLR 130 V+E +R G++D +V++ + P +P +TS +G+ + + +L + LP L Sbjct: 123 VAEAVRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLP-LM 181 Query: 131 KSQGNVINISSLVGAIGQAQAVP-----YVATKGAVTAMTKALALDE-SPYGVRVNCISP 184 K G+ + +S I + +P + K A+ + + LA + VRVNCIS Sbjct: 182 KEGGSALALSY----IASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISA 237 Query: 185 GNIWTPLWEELAALMPDP------RATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 G PL A+ + I PL + + +VG AA+FL S A Sbjct: 238 G----PLKSRAASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARA 293 Query: 238 CTGIELLVTGGAE-LGYGCKASRSTP 262 TG L V G +G + TP Sbjct: 294 VTGATLYVDNGLHAMGQALDSKSLTP 319 >1OC2-A nrPDB Length = 348 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 17/124 (13%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNS--GARVVICDK-DESGGRA-LEQELPGAV-FILCDVT 64 K ++VTGG IG+ V N+ V + DK +G +A LE L V ++ D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 + V L + + D +V H + + S + N +GTYTL + Sbjct: 65 DAELVDKLAA-------KADAIV-----HYAAESHNDNSLNDPSPFIHTNFIGTYTLLEA 112 Query: 125 ALPY 128 A Y Sbjct: 113 ARKY 116 >3N58-A nrPDB Length = 464 Score = 30.0 bits (66), Expect = 1.00, Method: Compositional matrix adjust. Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 13/99 (13%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCD 62 T AGKV VV G G +G G ++ +GARV + + D AL+ + G + D Sbjct: 241 TDVMMAGKVAVVCGYG-DVGKGSAQSLAGAGARVKVTEVDPIC--ALQAAMDGFEVVTLD 297 Query: 63 ---------VTQEDDVKTLVSETIRRFGRLDCVVNNAGH 92 VT + + + +R+ + C+V N GH Sbjct: 298 DAASTADIVVTTTGNKDVITIDHMRKMKDM-CIVGNIGH 335 >3GIU-A nrPDB Length = 215 Score = 30.0 bits (66), Expect = 1.00, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 12/66 (18%) Query: 114 NLLGTYTLTKLALPYLRKSQGNVINIS------SLVGAIGQAQAVPYVATKGAVTAMTKA 167 +++GT+T+ KL LP K N+IN + +V AIGQA + A+T A Sbjct: 31 DIIGTHTIDKLKLPTSFKKVDNIINKTLASNHYDVVLAIGQA------GGRNAITPERVA 84 Query: 168 LALDES 173 + +D++ Sbjct: 85 INIDDA 90 >4LAT-A nrPDB Length = 265 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRA-FVNSGARVVIC-DKDESGGRALEQELPGAVFILC 61 GT + GK V V GGG G G V++ V+ G V +KD AL + Sbjct: 26 GTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVDHKVAVAGLAL 85 Query: 62 DVTQEDDVKTLVSETIRRF 80 V +E DV L +E +R+ Sbjct: 86 IVNKEVDVDNLTTEQLRQI 104 >5JXW-A nrPDB Length = 498 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVTQE 66 AGK +VV G G +G G + GARV++ + D AL+ + G V +L DV E Sbjct: 270 AGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEIDPIC--ALQASMEGYQVSVLEDVVSE 326 Query: 67 DDV-------KTLVSETIRRFGRLDCVVNNAGH 92 D+ K +++ R + + + N GH Sbjct: 327 ADIFITATGNKDVITVEHMRKMKENAYIANIGH 359 >5INF-A nrPDB Length = 538 Score = 28.1 bits (61), Expect = 3.8, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 194 ELAALMPDPRATIREGMLAQPLGRMGQPAEVGA 226 ELAA+ P+ RA ++E ++ R G P E A Sbjct: 465 ELAAVPPEERAAVKENLVDDYRRRFGNPYEAAA 497 >1KEU-A nrPDB Length = 361 Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 23/126 (18%) Query: 12 VVVTGGGRGIGAGIVRAFV-NSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 +++TGG IG+ +VR + N+ VV DK G LE L D+++ + Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGN-LES--------LSDISESNRYN 53 Query: 71 TL------VSETIRRFGRL--DCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 +E R F + D V+ H + + S G +E N++GTY L Sbjct: 54 FEHADICDSAEITRIFEQYQPDAVM-----HLAAESHVDRSITGPAAFIETNIVGTYALL 108 Query: 123 KLALPY 128 ++A Y Sbjct: 109 EVARKY 114 >6GBN-A nrPDB Length = 438 Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD 42 AT AGKV VV G G +G G + +GARV++ + D Sbjct: 212 ATDVMMAGKVAVVAGYG-DVGKGSAASLRGAGARVIVTEID 251 >3I6T-A nrPDB Length = 381 Score = 27.3 bits (59), Expect = 6.3, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 11/66 (16%) Query: 114 NLLGTYTLTKLALPYL-RKSQG----------NVINISSLVGAIGQAQAVPYVATKGAVT 162 ++ +TL L+LP R+ G V+ + + GA+G +A P+V G+V Sbjct: 8 QIIAGFTLWHLSLPVTARRDHGIGSVAGAVEVVVLRLQADSGAVGYGEASPWVVFTGSVE 67 Query: 163 AMTKAL 168 A AL Sbjct: 68 ATYAAL 73 >4KUG-A nrPDB Length = 290 Score = 27.3 bits (59), Expect = 7.7, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE 43 K V V G G +GAGIV+AF G V++ D E Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKE 34 >2Q1W-A nrPDB Length = 333 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 5/88 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 K V +TG IG+ I + G +VV D +G R ++ P F+ + V Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSIADHALV 81 Query: 70 KTLVSETIRRFGRLDCVVNNAGHHPPPQ 97 L+ + + D VV+ A + P Sbjct: 82 NQLIGDL-----QPDAVVHTAASYKDPD 104 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5JS6-A nrPDB 342 8e-95 2PNF-A nrPDB 255 9e-69 4JRO-A nrPDB 244 2e-65 3RSH-A nrPDB 242 1e-64 2C07-A nrPDB 242 2e-64 2UVD-A nrPDB 241 3e-64 3EMK-A nrPDB 240 4e-64 2HQ1-A nrPDB 239 8e-64 3OSU-A nrPDB 239 1e-63 5ITV-A nrPDB 234 2e-62 1Q7C-A nrPDB 233 7e-62 3FTP-A nrPDB 232 1e-61 4M8S-A nrPDB 232 1e-61 3LYL-A nrPDB 232 2e-61 5CDY-A nrPDB 231 2e-61 3WOH-A nrPDB 230 6e-61 3O4R-A nrPDB 228 3e-60 3F9I-A nrPDB 227 4e-60 1GEE-A nrPDB 227 6e-60 3AUT-A nrPDB 225 1e-59 4DMM-A nrPDB 225 2e-59 4BO1-A nrPDB 224 2e-59 2NM0-A nrPDB 224 3e-59 3GRP-A nrPDB 224 3e-59 4NBT-A nrPDB 223 4e-59 1AE1-A nrPDB 223 4e-59 2PH3-A nrPDB 222 2e-58 2ZAT-A nrPDB 220 6e-58 2AE2-A nrPDB 219 9e-58 4K6F-A nrPDB 218 3e-57 1GEG-A nrPDB 218 3e-57 5OJG-A nrPDB 217 3e-57 4CQL-A nrPDB 217 5e-57 4RZH-A nrPDB 216 7e-57 4KMS-A nrPDB 216 8e-57 4IIN-A nrPDB 215 2e-56 2EW8-A nrPDB 215 2e-56 3EZL-A nrPDB 214 3e-56 1NFF-A nrPDB 214 3e-56 5OVL-A nrPDB 214 4e-56 2CDH-G nrPDB 213 5e-56 1YXM-A nrPDB 213 6e-56 4NBV-A nrPDB 212 1e-55 6NRP-A nrPDB 212 1e-55 4CQM-B nrPDB 212 1e-55 3OEC-A nrPDB 212 2e-55 5T5Q-A nrPDB 211 2e-55 3R3S-A nrPDB 211 3e-55 3VZS-A nrPDB 210 5e-55 5OVJ-A nrPDB 209 1e-54 5U9P-A nrPDB 208 2e-54 2Q2Q-A nrPDB 208 2e-54 6CI9-A nrPDB 208 3e-54 4IIV-A nrPDB 206 7e-54 5VT6-A nrPDB 206 8e-54 3WYE-A nrPDB 206 9e-54 1X1T-A nrPDB 205 1e-53 1O5I-A nrPDB 205 1e-53 3UVE-A nrPDB 205 2e-53 4Z9Y-A nrPDB 204 3e-53 1K2W-A nrPDB 204 3e-53 3W8F-A nrPDB 203 4e-53 1UZM-A nrPDB 203 5e-53 4DBZ-A nrPDB 203 7e-53 5YSS-A nrPDB 202 1e-52 3V2H-A nrPDB 202 1e-52 3T7C-A nrPDB 202 1e-52 2HSD-A nrPDB 200 4e-52 3WTC-A nrPDB 200 4e-52 4MOW-A nrPDB 200 5e-52 4AVY-A nrPDB 200 6e-52 4RZI-B nrPDB 200 6e-52 1DOH-A nrPDB 199 1e-51 1AHH-A nrPDB 198 2e-51 4FC7-A nrPDB 198 2e-51 3D3W-A nrPDB 197 3e-51 3RWB-A nrPDB 197 4e-51 3V2G-A nrPDB 197 4e-51 4E6P-A nrPDB 197 4e-51 2P91-A nrPDB 197 5e-51 4IS3-A nrPDB 195 1e-50 2AG5-A nrPDB 195 1e-50 1CYD-A nrPDB 195 2e-50 5EJ2-A nrPDB 194 3e-50 3OIC-A nrPDB 194 3e-50 4HP8-A nrPDB 194 4e-50 2B4Q-A nrPDB 193 4e-50 5JY1-A nrPDB 193 7e-50 1HXH-A nrPDB 192 1e-49 2FWM-X nrPDB 192 1e-49 3A28-C nrPDB 192 2e-49 5TF4-A nrPDB 191 3e-49 2CFC-A nrPDB 190 5e-49 5B1Y-A nrPDB 188 2e-48 3V8B-A nrPDB 187 4e-48 3U5T-A nrPDB 186 6e-48 3K2E-A nrPDB 186 8e-48 3ZV3-A nrPDB 185 2e-47 3UN1-A nrPDB 185 2e-47 3UF0-A nrPDB 183 9e-47 3GRK-A nrPDB 183 9e-47 4GKB-A nrPDB 182 1e-46 4M89-A nrPDB 181 2e-46 3U4C-A nrPDB 179 1e-45 1BDB-A nrPDB 179 1e-45 2YW9-A nrPDB 179 1e-45 1H5Q-A nrPDB 179 1e-45 3GDF-A nrPDB 177 4e-45 5O3Z-A nrPDB 175 2e-44 5KOI-A nrPDB 175 3e-44 1E3W-A nrPDB 174 3e-44 4TRR-A nrPDB 174 4e-44 5YCX-A nrPDB 173 5e-44 4RGB-A nrPDB 173 8e-44 2O23-A nrPDB 173 8e-44 2BGM-A nrPDB 172 1e-43 5CFZ-A nrPDB 171 2e-43 4CR6-A nrPDB 171 2e-43 4EGF-A nrPDB 171 4e-43 3PXX-A nrPDB 170 4e-43 4JQC-A nrPDB 170 6e-43 2GDZ-A nrPDB 169 1e-42 5IZ4-A nrPDB 169 1e-42 4ALL-A nrPDB 169 1e-42 1W73-A nrPDB 162 2e-40 2X9N-A nrPDB 161 2e-40 4DA9-A nrPDB 160 4e-40 3OML-A nrPDB 160 5e-40 3RKU-A nrPDB 158 3e-39 3PPI-A nrPDB 156 8e-39 2PD3-A nrPDB 155 2e-38 2NWQ-A nrPDB 153 1e-37 1P33-A nrPDB 149 1e-36 4DRY-A nrPDB 148 2e-36 5PGZ-A nrPDB 145 2e-35 2QHX-A nrPDB 145 3e-35 2BFA-A nrPDB 144 3e-35 5ILO-A nrPDB 142 2e-34 3DWF-A nrPDB 141 3e-34 3KZV-A nrPDB 141 3e-34 3UCF-A nrPDB 137 5e-33 1N5D-A nrPDB 134 4e-32 3E9N-A nrPDB 133 7e-32 2HRB-A nrPDB 132 1e-31 3BHI-A nrPDB 128 2e-30 1SNY-A nrPDB 124 3e-29 4Q9N-A nrPDB 120 5e-28 3O26-A nrPDB 119 9e-28 4HBG-A nrPDB 119 9e-28 1FJH-A nrPDB 119 1e-27 5L51-A nrPDB 119 2e-27 2DKN-A nrPDB 115 2e-26 5TQV-A nrPDB 114 3e-26 3U9L-A nrPDB 111 2e-25 1B15-A nrPDB 111 3e-25 5LCX-A nrPDB 104 5e-23 5WQO-A nrPDB 95 2e-20 Sequences not found previously or not previously below threshold: 3OIG-A nrPDB 174 4e-44 4ZJU-A nrPDB 174 4e-44 4NR0-A nrPDB 170 4e-43 4J3F-A nrPDB 166 1e-41 5I9N-A nrPDB 162 2e-40 4NK4-A nrPDB 146 9e-36 1A27-A nrPDB 124 4e-29 6CGE-A nrPDB 123 1e-28 2O2S-A nrPDB 112 2e-25 1ENP-A nrPDB 111 3e-25 1MG5-A nrPDB 104 5e-23 2NTV-A nrPDB 102 2e-22 3F4B-A nrPDB 99 2e-21 4OYR-A nrPDB 96 2e-20 2PTG-A nrPDB 95 3e-20 4Z3K-A nrPDB 88 3e-18 4HWK-A nrPDB 88 3e-18 1OAA-A nrPDB 87 6e-18 2O2Y-A nrPDB 85 3e-17 3ORF-A nrPDB 61 5e-10 3SLK-A nrPDB 61 6e-10 4LIS-A nrPDB 60 1e-09 2PK3-A nrPDB 56 1e-08 2Q1W-A nrPDB 55 3e-08 1OOE-A nrPDB 55 4e-08 6BWL-A nrPDB 53 1e-07 1VL0-A nrPDB 51 4e-07 3RFT-A nrPDB 51 5e-07 1UDA-A nrPDB 50 9e-07 1DIR-A nrPDB 48 6e-06 2GN9-A nrPDB 46 1e-05 1RKX-A nrPDB 46 2e-05 6GCS-E nrPDB 46 2e-05 1I3M-A nrPDB 44 5e-05 4R1T-A nrPDB 44 6e-05 2PZM-A nrPDB 44 6e-05 4G5H-A nrPDB 44 7e-05 3ENK-A nrPDB 44 7e-05 4J2O-A nrPDB 44 8e-05 4PVC-A nrPDB 43 2e-04 3SXP-A nrPDB 42 2e-04 1Z45-A nrPDB 42 3e-04 2NNL-D nrPDB 42 3e-04 2EXX-A nrPDB 42 3e-04 1BXK-A nrPDB 42 3e-04 1KEU-A nrPDB 41 7e-04 5N2I-A nrPDB 41 7e-04 5F5N-A nrPDB 40 0.001 2HUN-A nrPDB 40 0.001 5B6K-A nrPDB 39 0.001 3HFS-A nrPDB 39 0.002 5K1S-A nrPDB 39 0.002 1R66-A nrPDB 39 0.002 4KTT-E nrPDB 39 0.002 5YWN-A nrPDB 39 0.003 1OC2-A nrPDB 38 0.004 3OND-A nrPDB 38 0.004 3NJ4-A nrPDB 38 0.005 1LU9-A nrPDB 38 0.005 3N58-A nrPDB 38 0.005 2C20-A nrPDB 38 0.005 1GY8-A nrPDB 38 0.005 6ACF-A nrPDB 37 0.010 3LK7-A nrPDB 36 0.015 2C54-A nrPDB 36 0.015 5INT-A nrPDB 36 0.016 4EJ6-A nrPDB 36 0.018 6G2J-P nrPDB 36 0.018 3SC6-A nrPDB 36 0.018 4K28-A nrPDB 36 0.022 3X2F-A nrPDB 35 0.035 1YB5-A nrPDB 35 0.037 6BII-A nrPDB 35 0.041 1O89-A nrPDB 35 0.043 3H9U-A nrPDB 34 0.046 2GGS-A nrPDB 34 0.047 4DGK-A nrPDB 34 0.055 1ZZE-A nrPDB 34 0.057 2Z95-A nrPDB 34 0.062 4WPG-A nrPDB 34 0.067 5ENV-A nrPDB 34 0.070 6DEB-A nrPDB 34 0.072 2HK7-A nrPDB 34 0.073 3VPX-A nrPDB 34 0.075 4BKP-A nrPDB 34 0.084 5JXW-A nrPDB 34 0.091 3BIC-A nrPDB 34 0.096 2Q4B-A nrPDB 33 0.100 4EUF-A nrPDB 33 0.10 3PEF-A nrPDB 33 0.14 4J6F-A nrPDB 33 0.14 6GBN-A nrPDB 33 0.15 4EJ0-A nrPDB 33 0.15 3DMF-A nrPDB 33 0.16 4J90-A nrPDB 33 0.17 4MIT-A nrPDB 33 0.17 4WOK-A nrPDB 33 0.19 5GUP-L nrPDB 33 0.22 6C6P-A nrPDB 32 0.22 4KUG-A nrPDB 32 0.24 3IP1-A nrPDB 32 0.30 1MLD-A nrPDB 32 0.31 1ZDL-A nrPDB 32 0.31 2VN8-A nrPDB 32 0.34 4B4O-A nrPDB 32 0.34 5BUT-A nrPDB 32 0.35 2HMT-A nrPDB 32 0.36 1E3J-A nrPDB 32 0.38 3D64-A nrPDB 31 0.38 1Z1W-A nrPDB 31 0.43 4WLE-A nrPDB 31 0.46 3PVZ-A nrPDB 31 0.49 1EDZ-A nrPDB 31 0.51 6BI4-A nrPDB 31 0.55 1IE3-A nrPDB 31 0.56 2EER-A nrPDB 31 0.57 2OWO-A nrPDB 31 0.58 6ACQ-A nrPDB 31 0.71 4N7R-A nrPDB 31 0.73 2DFV-A nrPDB 31 0.75 3S2F-A nrPDB 30 1.0 4B4V-A nrPDB 30 1.1 1JAY-A nrPDB 29 1.5 4A5O-A nrPDB 29 1.5 3COS-A nrPDB 29 1.6 3ZU2-A nrPDB 29 1.7 3DC2-A nrPDB 29 1.8 2V6G-A nrPDB 29 1.8 2X86-A nrPDB 29 1.9 1LLU-A nrPDB 29 2.1 5AOV-A nrPDB 29 2.2 6C55-A nrPDB 29 2.3 3R9I-A nrPDB 29 2.3 6BMQ-A nrPDB 29 2.3 2WEK-A nrPDB 29 2.4 1ZCJ-A nrPDB 29 2.4 1JPH-A nrPDB 29 2.5 1V8B-A nrPDB 29 2.5 3HDH-A nrPDB 29 2.6 4A10-A nrPDB 29 2.7 1F14-A nrPDB 29 2.9 7REQ-A nrPDB 29 2.9 3FBG-A nrPDB 29 2.9 1EQ2-A nrPDB 29 3.1 3ZWA-A nrPDB 29 3.2 1C0L-A nrPDB 28 3.3 4N18-A nrPDB 28 3.3 1ZEJ-A nrPDB 28 3.3 1DB3-A nrPDB 28 3.3 3G1U-A nrPDB 28 3.4 2Q1T-A nrPDB 28 3.7 3L07-A nrPDB 28 3.8 2ZJ1-A nrPDB 28 4.0 3H0K-A nrPDB 28 4.0 4EKJ-A nrPDB 28 4.1 6FK3-A nrPDB 28 4.4 1U3W-A nrPDB 28 4.5 4GBJ-A nrPDB 28 4.7 4UUP-A nrPDB 28 5.0 3K30-A nrPDB 28 5.0 2AXQ-A nrPDB 28 5.2 5U9C-A nrPDB 28 5.5 4AF0-B nrPDB 28 5.5 1NHQ-A nrPDB 28 5.7 3K96-A nrPDB 28 6.0 4E0B-A nrPDB 28 6.0 2MKI-A nrPDB 28 6.2 4W5U-B nrPDB 28 6.4 3K4W-A nrPDB 28 6.4 5TC4-A nrPDB 28 6.5 4XRR-A nrPDB 28 6.7 3DOJ-A nrPDB 27 7.5 2BTW-A nrPDB 27 7.5 6AZ1-E nrPDB 27 8.3 5ZQZ-B nrPDB 27 8.3 3RI6-A nrPDB 27 8.4 4PZE-A nrPDB 27 9.0 2QTV-A nrPDB 27 9.3 5GXF-A nrPDB 27 9.3 6IHE-A nrPDB 27 9.7 4A26-A nrPDB 27 9.8 >5JS6-A nrPDB Length = 274 Score = 342 bits (878), Expect = 8e-95, Method: Composition-based stats. Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL Sbjct: 3 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 62 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT Sbjct: 63 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 122 Query: 121 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN Sbjct: 123 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 182 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG 240 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG Sbjct: 183 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG 242 Query: 241 IELLVTGGAELGYGCKASRSTPVDAPDIPS 270 IELLVTGGAELGYGCKASRSTPVDAPDIPS Sbjct: 243 IELLVTGGAELGYGCKASRSTPVDAPDIPS 272 >2PNF-A nrPDB Length = 248 Score = 255 bits (653), Expect = 9e-69, Method: Composition-based stats. Identities = 76/252 (30%), Positives = 123/252 (48%), Gaps = 14/252 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-----AVFI 59 + GKV +VTG RGIG I ++G+ V+I +A+ +E+ A + Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 ++ E+ + E +D +VNNAG + S + ++L++NL GT+ Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRD-KLFLRMSLLDWEEVLKVNLTGTF 121 Query: 120 TLTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 +T+ +L + ++ G ++NISS+VG G V Y TK + TK+LA + +P V Sbjct: 122 LVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVL 181 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VN ++PG I T + L+ ++ PLGR G P EV +FL SE A++ Sbjct: 182 VNAVAPGFIETDMTAVLS------EEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASY 235 Query: 238 CTGIELLVTGGA 249 TG + V GG Sbjct: 236 ITGEVIHVNGGM 247 >4JRO-A nrPDB Length = 271 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 79/257 (30%), Positives = 121/257 (47%), Gaps = 14/257 (5%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-----KDESGGRALEQELPGA 56 + GKV VVTGG RGIG I GA + E + + + Sbjct: 22 SNAMTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEV 81 Query: 57 VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 + +V +DV + I RFGR+D +VNNAG + + ++ +NL Sbjct: 82 EAMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDE-WDDVININLK 140 Query: 117 GTYTLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 GT+ TK +++ G +IN++S+VG IG A YVA+K V +TK A + +P Sbjct: 141 GTFLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPR 200 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEA 235 G+ VN ++PG I T + ++L T + PLG G ++ A +FLAS+A Sbjct: 201 GINVNAVAPGFITTDMTDKLD------EKTKEAMLAQIPLGAYGTTEDIANAVLFLASDA 254 Query: 236 N-FCTGIELLVTGGAEL 251 + + TG L V GG + Sbjct: 255 SKYITGQTLSVDGGMVM 271 >3RSH-A nrPDB Length = 251 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 81/254 (31%), Positives = 122/254 (48%), Gaps = 10/254 (3%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-GAVFI 59 M+ GKV +VTG RGIG I GA+V+ ESG +A+ L + Sbjct: 4 MSQFMNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGM 63 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 +VT + ++ ++ FG +D +VNNAG + + ++E NL + Sbjct: 64 ALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLM-RMKEEEWSDIMETNLTSIF 122 Query: 120 TLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 L+K L ++K QG +IN+ S+VG +G A Y A K V TK++A + + GV Sbjct: 123 RLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVT 182 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANF 237 VN ++PG I T + + L + P GR+G P E+ +A FLAS EA + Sbjct: 183 VNTVAPGFIETDMTKALN------DEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAY 236 Query: 238 CTGIELLVTGGAEL 251 TG L V GG + Sbjct: 237 ITGETLHVNGGMYM 250 >2C07-A nrPDB Length = 285 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 63/249 (25%), Positives = 119/249 (47%), Gaps = 13/249 (5%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF----ILCDV 63 KV +VTG GRGIG I + S + V+ + + ++ E+ + DV Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 ++++++ ++++ + +D +VNNAG + + + +L NL + +T+ Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDE-WEDVLRTNLNSLFYITQ 161 Query: 124 LALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 + ++ G +INISS+VG G Y ++K V TK+LA + + + VN I Sbjct: 162 PISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAI 221 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I + + ++++ + + P GRMG P EV A FL+S+ + + G Sbjct: 222 APGFISSDMTDKIS------EQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGR 275 Query: 242 ELLVTGGAE 250 ++ GG Sbjct: 276 VFVIDGGLS 284 >2UVD-A nrPDB Length = 246 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 116/252 (46%), Gaps = 14/252 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELPG----AVFILC 61 GKV +VTG RGIG I GA VV+ +E + E+ A+ + Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DV +DV +V +T+ FG++D +VNNAG + + ++ NL G + Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGV-TKDNLLMRMKEEEWDTVINTNLKGVFLC 120 Query: 122 TKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 TK +R+ G ++NI+S+VG G YVA K V +TK A + + + VN Sbjct: 121 TKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVN 180 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCT 239 I+PG I T + + L + E + P + G+ ++ A F AS+ + + T Sbjct: 181 AIAPGFIATDMTDVLDENIK------AEMLKLIPAAQFGEAQDIANAVTFFASDQSKYIT 234 Query: 240 GIELLVTGGAEL 251 G L V GG + Sbjct: 235 GQTLNVDGGMVM 246 >3EMK-A nrPDB Length = 246 Score = 240 bits (613), Expect = 4e-64, Method: Composition-based stats. Identities = 78/248 (31%), Positives = 120/248 (48%), Gaps = 10/248 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-LCDVTQ 65 G+ +VTG G+G I RA GA V + E + L EL +F+ +++ Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSD 64 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + VK L + G +D +VNNAG S + + +L +NL + LT+ Sbjct: 65 REAVKALGQKAEEEMGGVDILVNNAGITRD-GLFVRMSDEDWDAVLTVNLTSVFNLTREL 123 Query: 126 -LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 P +R+ G +INI+S+VG G Y A+K + +K+LA + + V VNCI+P Sbjct: 124 THPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAP 183 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIEL 243 G I + + +L D M P+ RMG A++ AA V+LAS+ A + TG L Sbjct: 184 GFIESAMTGKLNEKQKD------AIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTL 237 Query: 244 LVTGGAEL 251 V GG + Sbjct: 238 HVNGGMAM 245 >2HQ1-A nrPDB Length = 247 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 116/254 (45%), Gaps = 14/254 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD-----ESGGRALEQELPGAVFI 59 + GK +VTG RG+G I N GA +V+ ++ + V Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 DV +DV+ +V + FGR+D +VNNAG + S + + +L NL Y Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRD-TLMLKMSEKDWDDVLNTNLKSAY 119 Query: 120 TLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 TK L++ G +INI+S+ G IG A Y A+K + TK++A + + G+ Sbjct: 120 LCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIY 179 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANF 237 N ++PG I T + + L P + PL R G P EV FLAS ++N+ Sbjct: 180 CNAVAPGIIKTDMTDVL------PDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 238 CTGIELLVTGGAEL 251 TG + + GG + Sbjct: 234 ITGQVINIDGGLVM 247 >3OSU-A nrPDB Length = 246 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 14/249 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICD-----KDESGGRALEQELPGAVFILCDVT 64 K +VTG RGIG I G V + K E+ ++ + + I +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 D+VK ++ E + +FG LD +VNNAG Q + +++ NL G + + Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLM-RMKEQEWDDVIDTNLKGVFNCIQK 123 Query: 125 ALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 A P LR+ G +IN+SS+VGA+G YVATK V +TK+ A + + G+ VN ++ Sbjct: 124 ATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVA 183 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242 PG I + + + L+ + + + + PL R GQ ++ FLAS+ A + TG Sbjct: 184 PGFIVSDMTDALSDELKE------QMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQT 237 Query: 243 LLVTGGAEL 251 + V GG + Sbjct: 238 IHVNGGMYM 246 >5ITV-A nrPDB Length = 255 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 82/252 (32%), Positives = 131/252 (51%), Gaps = 7/252 (2%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA--VFILCD 62 K V++TGG GIG V+AF+ A VV+ D DE+ G A+ ++ F+ D Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTD 62 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 +T E + V + FG LD ++NNAG E + ++L++NL G + ++ Sbjct: 63 ITDEAACQHAVESAVHTFGGLDVLINNAGIEI-VAPIHEMELSDWNKVLQVNLTGMFLMS 121 Query: 123 KLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 K AL ++ +GN+IN S+ G + Y A+KG V +TK++A+D + + +RVNC Sbjct: 122 KHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNC 181 Query: 182 ISPGNIWTPLWEE--LAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238 + PG I TPL E+ L +E PL R+G+P E+ +FLAS+ +++ Sbjct: 182 VCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYM 241 Query: 239 TGIELLVTGGAE 250 TG + GG Sbjct: 242 TGSAITADGGYT 253 >1Q7C-A nrPDB Length = 244 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 75/250 (30%), Positives = 122/250 (48%), Gaps = 10/250 (4%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-GAVFILCDV 63 + GK+ +VTG RGIG I GA+V+ E+G +A+ L ++ +V Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV 60 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 T +++++ + FG +D +VNNAG + + ++E NL + L+K Sbjct: 61 TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE-WNDIIETNLSSVFRLSK 119 Query: 124 LALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 + ++K G +I I S+VG +G + A K + +K+LA + + G+ VN + Sbjct: 120 AVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVV 179 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I T + AL D RA I + P GR+G E+ A FLAS+ A + TG Sbjct: 180 APGFIETDMTR---ALSDDQRAGI---LAQVPAGRLGGAQEIANAVAFLASDEAAYITGE 233 Query: 242 ELLVTGGAEL 251 L V GG + Sbjct: 234 TLHVNGGMYM 243 >3FTP-A nrPDB Length = 270 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 119/251 (47%), Gaps = 13/251 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR----ALEQELPGAVFILCD 62 +V +VTG RGIG I GA V+ E+G A +Q + + Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLN 85 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V V LV T++ FG L+ +VNNAG Q + +++ NL + L+ Sbjct: 86 VNDATAVDALVESTLKEFGALNVLVNNAGI-TQDQLAMRMKDDEWDAVIDTNLKAVFRLS 144 Query: 123 KLAL-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + L P ++ G ++NI+S+VG+ G V Y A K V MT+ALA + G+ VNC Sbjct: 145 RAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNC 204 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTG 240 ++PG I T + + L P+ PLGR+G P ++ A FLAS +A + TG Sbjct: 205 VAPGFIDTDMTKGL------PQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITG 258 Query: 241 IELLVTGGAEL 251 L V GG + Sbjct: 259 TTLHVNGGMFM 269 >4M8S-A nrPDB Length = 248 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 127/254 (50%), Gaps = 11/254 (4%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP--GAVFI 59 + +GK+ +VTG RGIGA I +GA+V+ ESG A+ + L G Sbjct: 1 MSTQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGR 60 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 + + + + V+ L+++ + FG+LD +VNNAG + + ++++NL + Sbjct: 61 VLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLM-RMKEEEWDDIMQVNLKSVF 119 Query: 120 TLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 +K L +++ G +INI+S+VG +G A Y A K + +K++A + G+ Sbjct: 120 RASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGIT 179 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VNC++PG I T + L P T + LGR G ++ A +FLAS+ A + Sbjct: 180 VNCVAPGFIDTDMTRAL------PEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKY 233 Query: 238 CTGIELLVTGGAEL 251 TG L V GG + Sbjct: 234 ITGQTLHVNGGMLM 247 >3LYL-A nrPDB Length = 247 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 118/253 (46%), Gaps = 13/253 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE----QELPGAVFIL 60 KV +VTG RGIG + A + GA VV ++ E ++ A ++ Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 +++ + ++ +E +D +VNNAG S ++ ++ NL + Sbjct: 61 LNISDIESIQNFFAEIKAENLAIDILVNNAGITRDN-LMMRMSEDEWQSVINTNLSSIFR 119 Query: 121 LTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 ++K + ++K G +I+I S+VG+ G Y A K V +K+LA + + + V Sbjct: 120 MSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITV 179 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N ++PG I T + ++L AT P G++G+P ++ AA FLAS EA + Sbjct: 180 NVVAPGFIATDMTDKLTDEQKSFIAT------KIPSGQIGEPKDIAAAVAFLASEEAKYI 233 Query: 239 TGIELLVTGGAEL 251 TG L V GG + Sbjct: 234 TGQTLHVNGGMYM 246 >5CDY-A nrPDB Length = 244 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 121/250 (48%), Gaps = 10/250 (4%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-GAVFILCDV 63 + GK+ +VTG RGIG I V GA V+ E G A+ L ++ +V Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNV 60 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + T+++ FG +D +VNNAG + ++ +++ NL + L+K Sbjct: 61 VDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDE-WQDIIDTNLTSVFRLSK 119 Query: 124 LALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 + ++K G +I I S+VG +G A V Y A K V +K+LA + + G+ VN + Sbjct: 120 AVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVV 179 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I T + L D RA I + P R+G E+ +A FLAS+ A++ +G Sbjct: 180 APGFIETDMTRTLT---DDQRAGI---LAQVPANRLGDAKEIASAVAFLASDEASYISGE 233 Query: 242 ELLVTGGAEL 251 L V GG + Sbjct: 234 TLHVNGGMYM 243 >3WOH-A nrPDB Length = 251 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 71/258 (27%), Positives = 114/258 (44%), Gaps = 16/258 (6%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR-----ALEQELPG 55 M +GKV +VTGG RG+G + GA V I + +E+ Sbjct: 3 MTGPGALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGT 62 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 A CDV+ + V V G +D +VNNAG + + ++ NL Sbjct: 63 ARSYRCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRD-GLAASIKDEDYDAVMNTNL 121 Query: 116 LGTYTLTKLA-LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 G + K ++RK G++INISS+ G G A Y + K + +TK++A + + Sbjct: 122 KGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAE 181 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 VR N ++PG I T + ++L + + P+ R G+P EV FLA + Sbjct: 182 RNVRCNAVAPGLIATDMTQDLVDD--------SKRLDPVPMRRFGRPDEVAGLVAFLAGD 233 Query: 235 -ANFCTGIELLVTGGAEL 251 +++ TG + V GG + Sbjct: 234 ESSYITGQVVCVDGGMAM 251 >3O4R-A nrPDB Length = 261 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 68/254 (26%), Positives = 124/254 (48%), Gaps = 10/254 (3%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG----A 56 M A KV +VT GIG I R GA VV+ + + L G Sbjct: 7 MTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSV 66 Query: 57 VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 +C V + +D + LV+ ++ G +D +V+NA +P + + + + + L++N+ Sbjct: 67 TGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 126 Query: 117 GTYTLTKLALPYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 +TK +P + K G+V+ +SS+ PY +K A+ +TK LA++ +P Sbjct: 127 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPR 186 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-E 234 +RVNC++PG I T + + + + +++E + + R+G+P + FL S + Sbjct: 187 NIRVNCLAPGLIKTS-FSRMLWMDKEKEESMKETLR---IRRLGEPEDCAGIVSFLCSED 242 Query: 235 ANFCTGIELLVTGG 248 A++ TG ++V GG Sbjct: 243 ASYITGETVVVGGG 256 >3F9I-A nrPDB Length = 249 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 74/248 (29%), Positives = 122/248 (49%), Gaps = 14/248 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-LCDVTQ 65 GK ++TG GIG+ I R G++V+I +E ++L L I +C++ Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLAN 71 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 +++ L+S+T LD +V NAG Q F +++++NL + L + A Sbjct: 72 KEECSNLISKT----SNLDILVCNAGI-TSDTLAIRMKDQDFDKVIDINLKANFILNREA 126 Query: 126 LPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 + + +K G +INISS+VG G Y A+K + MTK+L+ + + G+ VN ++P Sbjct: 127 IKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAP 186 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIEL 243 G I + + ++L + PLG G P +V A FLAS A++ TG L Sbjct: 187 GFIKSDMTDKLN------EKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTL 240 Query: 244 LVTGGAEL 251 V GG + Sbjct: 241 HVNGGMLM 248 >1GEE-A nrPDB Length = 261 Score = 227 bits (578), Expect = 6e-60, Method: Composition-based stats. Identities = 93/261 (35%), Positives = 141/261 (54%), Gaps = 13/261 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-----GRALEQELPGAVFILC 61 GKVVV+TG G+G + F A+VV+ + + +++ A+ + Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DVT E DV LV I+ FG+LD ++NNAG P E S + ++++ NL G + Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSS-HEMSLSDWNKVIDTNLTGAFLG 123 Query: 122 TKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 ++ A+ Y ++ +G VIN+SS+ I V Y A+KG + MT+ LAL+ +P G+RV Sbjct: 124 SREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 183 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEANFC 238 N I PG I TP+ E A P+ RA + + P+G +G+P E+ A A +LA SEA++ Sbjct: 184 NNIGPGAINTPINAEKFA-DPEQRADVESMI---PMGYIGEPEEIAAVAAWLASSEASYV 239 Query: 239 TGIELLVTGGAELGYGCKASR 259 TGI L GG L +A R Sbjct: 240 TGITLFADGGMTLYPSFQAGR 260 >3AUT-A nrPDB Length = 269 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 96/263 (36%), Positives = 142/263 (53%), Gaps = 13/263 (4%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDES-----GGRALEQELPGAVFI 59 T KVVV+TGG G+G + F A+VVI + + +E+ A+ + Sbjct: 11 TDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIV 70 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 DVT+E+DV LV I+ FG LD ++NNAG P E S + ++++ NL G + Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPS-HELSLDNWNKVIDTNLTGAF 129 Query: 120 TLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 ++ A+ Y ++ +GNVIN+SS+ I V Y A+KG + MT+ LAL+ +P G+ Sbjct: 130 LGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGI 189 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEAN 236 RVN I PG + TP+ E A P RA + + P+G +G+P EV A A FLA S+A+ Sbjct: 190 RVNNIGPGAMNTPINAEKFA-DPVQRADVESMI---PMGYIGKPEEVAAVAAFLASSQAS 245 Query: 237 FCTGIELLVTGGAELGYGCKASR 259 + TGI L GG +A R Sbjct: 246 YVTGITLFADGGMTKYPSFQAGR 268 >4DMM-A nrPDB Length = 269 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 80/258 (31%), Positives = 123/258 (47%), Gaps = 18/258 (6%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-- 59 T ++ +VTG RGIG I +GA+V + +G A Sbjct: 21 MTALPLTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEA 80 Query: 60 ---LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 DV+QE +V+ L + I R+GRLD +VNNAG ++ +L+LNL Sbjct: 81 FAVKADVSQESEVEALFAAVIERWGRLDVLVNNAGITRD-TLLLRMKRDDWQSVLDLNLG 139 Query: 117 GTYTLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 G + ++ A L++ G +INI+S+VG +G Y A K V +TK +A + + Sbjct: 140 GVFLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASR 199 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 G+ VN ++PG I T + ELAA + + PLGR G+ AEV FLA++ Sbjct: 200 GITVNAVAPGFIATDMTSELAA---------EKLLEVIPLGRYGEAAEVAGVVRFLAADP 250 Query: 235 -ANFCTGIELLVTGGAEL 251 A + TG + + GG + Sbjct: 251 AAAYITGQVINIDGGLVM 268 >4BO1-A nrPDB Length = 269 Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 78/254 (30%), Positives = 113/254 (44%), Gaps = 13/254 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG----AVFI 59 GKV +VTG RGIG I GA V+ SG + + L + Sbjct: 22 SMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGL 81 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 + DV+ ++ V + + G+ VVNNAG + F ++ NL Y Sbjct: 82 VLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFD-VVNTNLNSLY 140 Query: 120 TLTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 L+K L + + G +INI S+VGA+G A Y A K + T+ALA + + Sbjct: 141 RLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAIT 200 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VN ++PG I T + EL P A + PLGR+GQ E+ FLAS+ A + Sbjct: 201 VNAVAPGFIDTDMTREL------PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAY 254 Query: 238 CTGIELLVTGGAEL 251 TG + V GG + Sbjct: 255 VTGATVPVNGGMYM 268 >2NM0-A nrPDB Length = 253 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 78/249 (31%), Positives = 124/249 (49%), Gaps = 16/249 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + + V+VTGG RGIG I RAF ++G +V I + G + + CD+T Sbjct: 19 HMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPE-------GFLAVKCDITDT 71 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + V+ E G ++ ++ NAG Q S + F ++E NL GT+ + K A Sbjct: 72 EQVEQAYKEIEETHGPVEVLIANAGV-TKDQLLMRMSEEDFTSVVETNLTGTFRVVKRAN 130 Query: 127 P-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 LR +G V+ ISS+VG +G A Y A+K + ++LA + + N ++PG Sbjct: 131 RAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPG 190 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELL 244 + T + + L + RA I + PLGR +P E+ A FLAS +A++ TG + Sbjct: 191 FVDTDMTKVLT---DEQRANI---VSQVPLGRYARPEEIAATVRFLASDDASYITGAVIP 244 Query: 245 VTGGAELGY 253 V GG +G+ Sbjct: 245 VDGGLGMGH 253 >3GRP-A nrPDB Length = 266 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 74/249 (29%), Positives = 116/249 (46%), Gaps = 10/249 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-LCDVT 64 + G+ +VTG GIG I R F GA V + E + + +L VF+ +++ Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLS 83 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 +K L R +D +VNNAG Q + +L +NL TLT+ Sbjct: 84 DRKSIKQLAEVAEREMEGIDILVNNAGITRD-GLFVRMQDQDWDDVLAVNLTAASTLTRE 142 Query: 125 ALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + +R+ G +INI+S+VG +G Y A K + +KALA + + + VNCI+ Sbjct: 143 LIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIA 202 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242 PG I + + ++L M P+ RMG E+ A V+LAS+ A + TG Sbjct: 203 PGFIKSAMTDKLN------EKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTGQT 256 Query: 243 LLVTGGAEL 251 L + GG + Sbjct: 257 LHINGGMAM 265 >4NBT-A nrPDB Length = 240 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 83/251 (33%), Positives = 130/251 (51%), Gaps = 16/251 (6%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVT 64 + GKV V+TGG +G+G I A+ GA+V+ D + L P + +VT Sbjct: 2 KKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD-----LTYSHPNVEGMYLNVT 56 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 V+ I ++G++D +VNNAG + T AQ + ++++NL G + LT+L Sbjct: 57 DVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQ-WDAVIDVNLKGVFNLTRL 115 Query: 125 ALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG--VRVNC 181 P ++ + G++INISS+VG G Y ATK V +T A + + G VRVN Sbjct: 116 VGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNA 175 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTG 240 I+PG I T + + + P+ + + L R+GQP E+ A+FLAS +A++ TG Sbjct: 176 IAPGYIMTDILKTV------PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTG 229 Query: 241 IELLVTGGAEL 251 + V GG L Sbjct: 230 QTINVNGGMRL 240 >1AE1-A nrPDB Length = 273 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 80/261 (30%), Positives = 123/261 (47%), Gaps = 8/261 (3%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL----EQELPGAV 57 G +VTGG +GIG IV GARV C ++E ++ Sbjct: 14 EGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVE 73 Query: 58 FILCDVTQEDDVKTLVSETIRRF-GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 +CD+ + L+ F G+L+ +VNNAG + ++ + + + ++ N Sbjct: 74 GSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGV-VIHKEAKDFTEKDYNIIMGTNFE 132 Query: 117 GTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 Y L+++A P L+ SQ GNVI +SS+ G Y A+KGA+ MTK+LA + + Sbjct: 133 AAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKD 192 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SE 234 +RVN ++PG I TPL E P + I ++ P+GR G+P EV A FL Sbjct: 193 NIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPA 252 Query: 235 ANFCTGIELLVTGGAELGYGC 255 A++ TG + GG G Sbjct: 253 ASYITGQIIWADGGFTANGGF 273 >2PH3-A nrPDB Length = 245 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 110/249 (44%), Gaps = 15/249 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL------PGAVFILCDV 63 + ++TG RGIG I G + I E P + ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + + LV + G LD +VNNAG + + +LE NL + T+ Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRD-TLLVRMKDEDWEAVLEANLSAVFRTTR 120 Query: 124 LALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 A+ + K++ G ++NI+S+VG +G YVA+K + T+A+A + + G+ VN + Sbjct: 121 EAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAV 180 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I T + E L P+ + P GR G+P EV A FL SE A + TG Sbjct: 181 APGFIETEMTERL------PQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQ 234 Query: 242 ELLVTGGAE 250 L V GG Sbjct: 235 TLCVDGGLT 243 >2ZAT-A nrPDB Length = 260 Score = 220 bits (561), Expect = 6e-58, Method: Composition-based stats. Identities = 67/248 (27%), Positives = 112/248 (45%), Gaps = 10/248 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG----AVFILCD 62 KV +VT GIG I R GA VV+ + + L G +C Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V + +D + LV+ + G +D +V+NA +P + + + + ++L +N+ T +T Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131 Query: 123 KLALPYLRKSQGNVINI-SSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 K +P + K G + I SS+ PY +K A+ +TK LA++ +P +RVNC Sbjct: 132 KAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNC 191 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTG 240 ++PG I T + L + R+G P + FL S +A++ TG Sbjct: 192 LAPGLIKTNFSQVLWMDKARKEYMKESLR----IRRLGNPEDCAGIVSFLCSEDASYITG 247 Query: 241 IELLVTGG 248 ++V GG Sbjct: 248 ETVVVGGG 255 >2AE2-A nrPDB Length = 260 Score = 219 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 80/262 (30%), Positives = 130/262 (49%), Gaps = 9/262 (3%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR----ALEQELPGA 56 MA G +VTGG RGIG GIV + GA V C +++ + Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKV 60 Query: 57 VFILCDVTQEDDVKTLVSETIRRF-GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 +CD++ + + L++ F G+L+ +VNNAG + ++ + + + ++ +N Sbjct: 61 EASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGI-VIYKEAKDYTVEDYSLIMSINF 119 Query: 116 LGTYTLTKLALPYLRKS-QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 Y L+ LA P+L+ S +GNV+ ISS+ GA+ Y ATKGA+ +T+ LA + + Sbjct: 120 EAAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAK 179 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-S 233 +RVN + PG I T L E+ P+ + + + + L RMG+P E+ A FL Sbjct: 180 DNIRVNGVGPGVIATSLV-EMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFP 238 Query: 234 EANFCTGIELLVTGGAELGYGC 255 A++ TG + V GG G Sbjct: 239 AASYVTGQIIYVDGGLMANCGF 260 >4K6F-A nrPDB Length = 255 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 113/252 (44%), Gaps = 13/252 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR-----ALEQELPGAVFILC 61 ++ VVTGG G+G + ++G RVV+ + G + Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPV 68 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DV D + + + +R G +D +VNNAG + + ++ NL + + Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRD-MTLRKLDKVNWDAVIRTNLDSVFNM 127 Query: 122 TK-LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 TK + + + G ++NISS+ G+ G Y A K + TK+LAL+ + GV VN Sbjct: 128 TKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVN 187 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCT 239 +SPG + T + + + D + + P GR+G+P EV A +L S EA F T Sbjct: 188 TVSPGYLATKMVTAIPQDILD-----TKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVT 242 Query: 240 GIELLVTGGAEL 251 G + + GG + Sbjct: 243 GSNIAINGGQHM 254 >1GEG-A nrPDB Length = 256 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 76/252 (30%), Positives = 121/252 (48%), Gaps = 13/252 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILCDVTQ 65 KV +VTG G+GIG I V G V I D +++ +A+ E+ AV + DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 D V V + + G D +VNNAG P E + + ++ +N+ G + A Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPS-TPIESITPEIVDKVYNINVKGVIWGIQAA 121 Query: 126 LPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + +K G +IN S G +G + Y ++K AV +T+ A D +P G+ VN Sbjct: 122 VEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 184 PGNIWTPLWEELAALMPD-----PRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANF 237 PG + TP+W E+ + + E LGR+ +P +V A +LAS ++++ Sbjct: 182 PGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDY 241 Query: 238 CTGIELLVTGGA 249 TG LL+ GG Sbjct: 242 MTGQSLLIDGGM 253 >5OJG-A nrPDB Length = 260 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 124/252 (49%), Gaps = 8/252 (3%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-----AVFIL 60 R+ GKV +VT +GIG I ++ GA VVI +++ + L I Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 + DD K LV T+++FG+++ +VNN G +P E S Q + +L E+N+ + Sbjct: 67 GHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQ 126 Query: 121 LTKLALPYLRK-SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 +TKL P++ K G +I +S Y TK + +T+ALA+ + +RV Sbjct: 127 MTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRV 186 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N I+PG I T + + L D + + + LGR+G P + +LAS ++++ Sbjct: 187 NGIAPGVIKTKMSQVLWDGGEDAEKELTD-IQEIALGRLGVPDDCAGTVAYLASDDSSYI 245 Query: 239 TGIELLVTGGAE 250 TG +++ GG + Sbjct: 246 TGEMIIIAGGVQ 257 >4CQL-A nrPDB Length = 261 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 70/261 (26%), Positives = 119/261 (45%), Gaps = 20/261 (7%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--------- 55 R + +VTG G GIG + GA V CD D + + + L G Sbjct: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 Query: 56 --AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLEL 113 DV++ + L+ + F R VV + + S + +++ + Sbjct: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 Query: 114 NLLGTYTLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD 171 NL GT+ +T+ A L + +G++INISS+VG +G Y A+K V +T+ A + Sbjct: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFL 231 +G+R N + PG I TP+ +++ P+ + + P+G +G P +V FL Sbjct: 187 LGRHGIRCNSVLPGFIATPMTQKV------PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 Query: 232 AS-EANFCTGIELLVTGGAEL 251 AS ++ + TG + VTGG + Sbjct: 241 ASEDSGYITGTSVEVTGGLFM 261 >4RZH-A nrPDB Length = 247 Score = 216 bits (551), Expect = 7e-57, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 120/255 (47%), Gaps = 18/255 (7%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQEL----PGAVFI 59 T +V +VTG RGIG A +G +VV+ + + A+ E+ A+ + Sbjct: 2 TALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAV 61 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 +V D+V L+ T+ +F R+D +VNNAG + ++ +++LNL G + Sbjct: 62 QANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRD-TLLLRMKLEDWQAVIDLNLTGVF 120 Query: 120 TLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 TK L++ G +INI+S+ G +G Y A K V TK +A + + GV Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVT 180 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE--AN 236 VN ++PG I T + E L A + PL R GQP EV FLA++ A Sbjct: 181 VNAVAPGFIATDMTENLNA---------EPILQFIPLARYGQPEEVAGTIRFLATDPAAA 231 Query: 237 FCTGIELLVTGGAEL 251 + TG V GG + Sbjct: 232 YITGQTFNVDGGMVM 246 >4KMS-A nrPDB Length = 249 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 68/244 (27%), Positives = 108/244 (44%), Gaps = 10/244 (4%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 + +VTGG RGIG N G VV +E G +V ++ + Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCWNVADFEECR 71 Query: 71 TLVSETIRRFGR-LDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 V E F + + +VNNAG + S Q + ++ +NL + ++ + + Sbjct: 72 QAVKEIEEEFKKPVSILVNNAGI-TKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQM 130 Query: 130 R-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIW 188 R + G ++NISS+ GQ Y A K + TKALA + + + VNCI+PG I Sbjct: 131 RNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYIA 190 Query: 189 TPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTG 247 T + + P + + + + P R+GQP E+ A FL E A F TG + + G Sbjct: 191 TEMVGAV------PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISING 244 Query: 248 GAEL 251 G + Sbjct: 245 GHNM 248 >4IIN-A nrPDB Length = 271 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 14/257 (5%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR-----ALEQELPGA 56 + ++ GK V++TG +GIGA I + + G +V I + + LE++ A Sbjct: 22 SNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKA 81 Query: 57 VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 I D E D + ++ G L +VNNAG + + + F +++ NL Sbjct: 82 AVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKT-EDFHHVIDNNLT 140 Query: 117 GTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 + + AL + KS+ G+V+N++S++G G Y A+KG + AM+K+ A + + Sbjct: 141 SAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALR 200 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 +R N ++PG I T + L + + + PL R+G EV A FL S+ Sbjct: 201 NIRFNSVTPGFIETDMNANLKDELK------ADYVKNIPLNRLGSAKEVAEAVAFLLSDH 254 Query: 235 ANFCTGIELLVTGGAEL 251 +++ TG L V GG + Sbjct: 255 SSYITGETLKVNGGLYM 271 >2EW8-A nrPDB Length = 249 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 77/249 (30%), Positives = 121/249 (48%), Gaps = 9/249 (3%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK--DESGGRALEQELPGAVFILCD 62 R K+ V+TGG GIG I F GA + I D A+ + + CD Sbjct: 3 QRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCD 62 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V+Q DV+ + I FGR D +VNNAG +P +E + + +++ E+N+ + + Sbjct: 63 VSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIP-FDELTFEQWKKTFEINVDSGFLMA 121 Query: 123 KLALPYLRK-SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 K +P +++ G +IN++S + Y++TK A T+ALA D G+ VN Sbjct: 122 KAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNA 181 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTG 240 I+P + T E A+ + + + A P R+ P ++ AA FLAS +A+F TG Sbjct: 182 IAPSLVRTATTE--ASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASFITG 237 Query: 241 IELLVTGGA 249 L V GG Sbjct: 238 QTLAVDGGM 246 >3EZL-A nrPDB Length = 256 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 114/253 (45%), Gaps = 14/253 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-----LC 61 + ++ VTGG GIG I + G RVV S R E A+ Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEG 70 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 +V D K + G +D +VNNAG + + + ++ +++ NL + + Sbjct: 71 NVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRK-MTREDWQAVIDTNLTSLFNV 129 Query: 122 TKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 TK + + + G +INISS+ G GQ Y K + T +LA + + GV VN Sbjct: 130 TKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVN 189 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCT 239 +SPG I T + + + + + + + P+ R+G P E+G+ +LAS E+ F T Sbjct: 190 TVSPGYIGTDMVKAIRPDV------LEKIVATIPVRRLGSPDEIGSIVAWLASEESGFST 243 Query: 240 GIELLVTGGAELG 252 G + + GG +G Sbjct: 244 GADFSLNGGLHMG 256 >1NFF-A nrPDB Length = 260 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 89/250 (35%), Positives = 131/250 (52%), Gaps = 15/250 (6%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK-DESGGRALEQELPGAVFILCDVT 64 R GKV +V+GG RG+GA VRA V GA+VV D DE G + A ++ DVT Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVT 63 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 Q K V + FG L +VNNAG E+ + ++++L++NL G + + Sbjct: 64 QPAQWKAAVDTAVTAFGGLHVLVNNAGILN-IGTIEDYALTEWQRILDVNLTGVFLGIRA 122 Query: 125 ALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + ++ +G++INISS+ G G Y ATK AV +TK+ AL+ P G+RVN I Sbjct: 123 VVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIH 182 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242 PG + TP+ + + E + LGR +P EV V+LAS+ +++ TG E Sbjct: 183 PGLVKTPMTD-----------WVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGAE 231 Query: 243 LLVTGGAELG 252 +V GG G Sbjct: 232 FVVDGGTVAG 241 >5OVL-A nrPDB Length = 300 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 66/249 (26%), Positives = 104/249 (41%), Gaps = 16/249 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + + V+VTGG RGIG I R G +V + + L + CDVT Sbjct: 66 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-------FGVQCDVTDS 118 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 V E G ++ +V NAG + + F +++ NL G + + A Sbjct: 119 AAVDRAFKEVEEHQGPVEVLVANAGIS-KDAFLMRMTEERFEEVINTNLTGAFRCAQRAS 177 Query: 127 PYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + RK G +I I S+ G G Y A K + M ++++ + + GV N ++PG Sbjct: 178 RTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPG 237 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELL 244 I T + L + P R+G EV A FLAS +A++ G + Sbjct: 238 YIDTEMTRALD------ERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 291 Query: 245 VTGGAELGY 253 V GG +G+ Sbjct: 292 VDGGMGMGH 300 >2CDH-G nrPDB Length = 244 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 75/246 (30%), Positives = 118/246 (47%), Gaps = 15/246 (6%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKD-----ESGGRALEQELPGAVFILCDVTQ 65 VVVVTG RGIG I + +G +V++ E + +E A+ DV++ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 E DV+ ++ I +G +D VVNNAG +Q + ++++LNL G + T+ A Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQ-WDEVIDLNLTGVFLCTQAA 121 Query: 126 LP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 ++K +G +INI+S+VG IG Y A K V +K A + + + VN + P Sbjct: 122 TKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCP 181 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA--SEANFCTGIE 242 G I + + +L ++ + PLGR GQP V FLA A++ TG Sbjct: 182 GFIASDMTAKLG------EDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQA 235 Query: 243 LLVTGG 248 + GG Sbjct: 236 FTIDGG 241 >1YXM-A nrPDB Length = 303 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 79/261 (30%), Positives = 128/261 (49%), Gaps = 17/261 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG---------AV 57 G+V +VTGG GIG IV+ + G+ VVI + ++ EL + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 I C++ E++V LV T+ FG+++ +VNN G E S++G+ +LE NL G Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP-AEHISSKGWHAVLETNLTG 134 Query: 118 TYTLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 T+ + K ++++ G+++NI + G AV A + V +TK+LAL+ + G Sbjct: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLA-QPLGRMGQPAEVGAAAVFLAS-E 234 +R+NC++PG I++ + + EG P R+G P EV + FL S Sbjct: 194 IRINCVAPGVIYS---QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 Query: 235 ANFCTGIELLVTGGAELGYGC 255 A+F TG + V GG L Sbjct: 251 ASFITGQSVDVDGGRSLYTHS 271 >4NBV-A nrPDB Length = 246 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 120/253 (47%), Gaps = 13/253 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV----FIL 60 + G+V ++TG GIG + F GA VV+CD E+ R L Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DVT+ D+V +V+ + R+D +VNNAG R + + F ++++NL G + Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGI-TKDARLAKMTEAQFDAVIDVNLKGVFN 119 Query: 121 LTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + + + +G ++N SS+VG G Y A+K V TK A + P GVRV Sbjct: 120 CAQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRV 179 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N + PG + T + + + + D + L R+ +PAE+ + FLAS +A++ Sbjct: 180 NAVCPGFVNTEILQTVPDKVLDGMTSSCW------LRRLAEPAEIASIYAFLASDDASYV 233 Query: 239 TGIELLVTGGAEL 251 G+ + +GG L Sbjct: 234 NGVAIEASGGMSL 246 >6NRP-A nrPDB Length = 263 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 66/248 (26%), Positives = 115/248 (46%), Gaps = 18/248 (7%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD-----ESGGRALEQELPGAVFILCDVT 64 + ++VTG RGIG I +G V + + E + ++ + +++ DV Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK- 123 + V+ ++ + + + G VV NAG P + Q + +++ +L G Y + K Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPA-LTDQDWDEVISTSLDGFYNVLKP 143 Query: 124 LALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 L +P + + G ++ +SS+ G +G V Y A K + TKALAL+ + + VNC+ Sbjct: 144 LIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCV 203 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 +PG I T + + + PL RMGQ EV + FL S+ A++ T Sbjct: 204 APGLIETEMVTD---------EVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQ 254 Query: 242 ELLVTGGA 249 + V GG Sbjct: 255 VISVNGGL 262 >4CQM-B nrPDB Length = 244 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 76/253 (30%), Positives = 122/253 (48%), Gaps = 13/253 (5%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV-FI 59 M + KV V GG RGIG + + G R+ + ++ G +A +L G Sbjct: 1 MHHHHHHMDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF 60 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 CDV +E DV+ E + GR++ +VN AG + T + L NLLG+ Sbjct: 61 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSM 119 Query: 120 TLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 K A+ +++ G+++N+ S+VG G + Y A+KG + ++ALA + + +R Sbjct: 120 LTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 179 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFC 238 VN ++PG + T + ++L PLGR G+ EV A VFL E+ + Sbjct: 180 VNVVAPGFVHTDMTKDLKE---------EHLKKNIPLGRFGETIEVAHAVVFLL-ESPYI 229 Query: 239 TGIELLVTGGAEL 251 TG L+V GG +L Sbjct: 230 TGHVLVVDGGLQL 242 >3OEC-A nrPDB Length = 317 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 67/274 (24%), Positives = 111/274 (40%), Gaps = 31/274 (11%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK----------------DESGGRA 48 R GKV +TG RG G GA +V D + R Sbjct: 42 NRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRL 101 Query: 49 LEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFR 108 +E++ + DV ++ +V E + FG +D +V+N G + Q + Sbjct: 102 VEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQ-GEVVSLTDQQWS 160 Query: 109 QLLELNLLGTYTLTKLALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 +L+ NL+G + + LP + R G+VI +SS VG G Y A+K V + Sbjct: 161 DILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLML 220 Query: 167 ALALDESPYGVRVNCISPGNIWTPL----------WEELAALMPDPRATIREGMLAQPLG 216 +LA + + +RVN ++PG + T + L + A + + P+ Sbjct: 221 SLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP 280 Query: 217 RMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGA 249 +P +V A +LAS+ A + G + V GG Sbjct: 281 -WVEPEDVSNAVAWLASDEARYIHGAAIPVDGGQ 313 >5T5Q-A nrPDB Length = 247 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 84/249 (33%), Positives = 127/249 (51%), Gaps = 13/249 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG---AVFILCDV 63 + + +V+TG GIG I F SGA +V+ D D G A L I D Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 66 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + DD + V+ + RFG +D +V +AG + + E S + + + +NL G + L K Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGIY-QAKPFAEMSDADWHRTISINLDGVFYLCK 125 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 ALP L++ +++ ++SL G Y ATKGA+ +MT+AL+ + +P RVN +S Sbjct: 126 RALPALKEDS-SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TRVNGVS 183 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIE 242 PG I TP+ EL D E M PL R+G+P+E+ + FL S A+F TG Sbjct: 184 PGIIETPMTSELLKTRMD------ETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGET 237 Query: 243 LLVTGGAEL 251 + V GG + Sbjct: 238 IQVNGGIYM 246 >3R3S-A nrPDB Length = 294 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 116/254 (45%), Gaps = 12/254 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA------LEQELPGAVFI 59 R + +VTGG GIG A+ GA V I A +E+ AV + Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 D++ E ++LV + G LD + AG ++ +++ F+Q +N+ + Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALF 165 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 +T+ A+P L K ++I SS+ + Y ATK A+ ++ LA + G+RV Sbjct: 166 WITQEAIPLLPK-GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRV 224 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N ++PG IWT L + I + P+ R GQPAE+ V+LAS E+++ Sbjct: 225 NIVAPGPIWT----ALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYV 280 Query: 239 TGIELLVTGGAELG 252 T V GG LG Sbjct: 281 TAEVHGVCGGEHLG 294 >3VZS-A nrPDB Length = 257 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 14/250 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI-----LCDVT 64 ++ VTGG GIG I + G RVV S R E A+ +V Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 D KT + G +D ++NNAG + + + +++ NL + +TK Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRK-MTRADWDAVIDTNLTSLFNVTKQ 133 Query: 125 ALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + + + G ++NISS+ G GQ Y K + T ALA + + GV VN +S Sbjct: 134 VIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVS 193 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIE 242 PG I T + + + + D + + P+ R+G P E+ + +L+S E+ F TG + Sbjct: 194 PGYIATDMVKAIRQDVLD------KIVATIPVKRLGLPEEIASICAWLSSEESGFSTGAD 247 Query: 243 LLVTGGAELG 252 + GG +G Sbjct: 248 FSLNGGLHMG 257 >5OVJ-A nrPDB Length = 256 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 66/249 (26%), Positives = 104/249 (41%), Gaps = 16/249 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + + V+VTGG RGIG I R G +V + + L + CDVT Sbjct: 22 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-------FGVQCDVTDS 74 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 V E G ++ +V NAG + + F +++ NL G + + A Sbjct: 75 AAVDRAFKEVEEHQGPVEVLVANAGIS-KDAFLMRMTEERFEEVINTNLTGAFRCAQRAS 133 Query: 127 PYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + RK G +I I S+ G G Y A K + M ++++ + + GV N ++PG Sbjct: 134 RTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPG 193 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELL 244 I T + L + P R+G EV A FLAS +A++ G + Sbjct: 194 YIDTEMTRALD------ERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 247 Query: 245 VTGGAELGY 253 V GG +G+ Sbjct: 248 VDGGMGMGH 256 >5U9P-A nrPDB Length = 265 Score = 208 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 117/251 (46%), Gaps = 11/251 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE----QELPGAVFILC 61 R G+ ++TG GRGIG + R +GA +VI D++E L E A + Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF 76 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DV + V+ + E R G +D +VNNAG + + L+ +NL G + + Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPL-DAFEPDDWHALMRVNLDGVFNV 135 Query: 122 TKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + ++ G +INI S+ + + PY ATKGAV +TK + D + YG++ N Sbjct: 136 AQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQAN 195 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEAN-FCT 239 ++PG T L L D A P GR GQ E+ AA+FLAS A+ F Sbjct: 196 GLAPGYFETELNRALV----DDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFVN 251 Query: 240 GIELLVTGGAE 250 G L V GG Sbjct: 252 GQTLFVDGGLT 262 >2Q2Q-A nrPDB Length = 255 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 76/252 (30%), Positives = 118/252 (46%), Gaps = 10/252 (3%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG--GRALEQELPGAVFILCDVT 64 GK +VTG GIG GI + +GA +V+ + + + AV D++ Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLS 61 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 ++ L + R FG +D +VNNAG E+ + + +++ LNL + T+L Sbjct: 62 DVAQIEALFALAEREFGGVDILVNNAGIQH-VAPVEQFPLESWDKIIALNLSAVFHGTRL 120 Query: 125 ALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 ALP +R ++ G +INI+S+ G +G YVA K V +TK + L+ + V N I Sbjct: 121 ALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAIC 180 Query: 184 PGNIWTPLWEEL----AALMPDPRATIREGML-AQPLGRMGQPAEVGAAAVFLASEA-NF 237 PG + TPL ++ AA DP + + QP P +G +FL SEA + Sbjct: 181 PGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQ 240 Query: 238 CTGIELLVTGGA 249 G V GG Sbjct: 241 VRGAAWNVDGGW 252 >6CI9-A nrPDB Length = 259 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 86/254 (33%), Positives = 126/254 (49%), Gaps = 14/254 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG----AVFIL 60 T G+ +VTGG +GIG GI F N+G VVI +++ +L G + Sbjct: 5 TSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVR 64 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DVT +D + V+ET+ R G LD V NAG P R E+ + Q+L +N GT Sbjct: 65 ADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPS-GRLEDLTPDDIEQVLGVNFKGTVY 123 Query: 121 LTKLALPYLRKSQ-GNVINISSLVG-AIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + AL L S G V+ SS+ G G Y A+K A + A++ +P + Sbjct: 124 IVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKIT 183 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 +N + PGNI T +E+ D A+ A P GR+G A++G AA+F A++ A + Sbjct: 184 INAVLPGNIMTEGLDEMGQDYLDQMAS------AIPAGRLGSVADIGNAALFFATDEAAY 237 Query: 238 CTGIELLVTGGAEL 251 TG L+V GG L Sbjct: 238 VTGQTLVVDGGQVL 251 >4IIV-A nrPDB Length = 267 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 67/249 (26%), Positives = 110/249 (44%), Gaps = 16/249 (6%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR-----ALEQELPGAVFILCDV 63 + V+VTG +GIG I R G + + ++ G A+ + DV Sbjct: 26 SRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDV 85 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + + ++ I + G VV+NAG P S + ++ NL Y + + Sbjct: 86 ANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPA-LSNDDWDAVIHTNLDSFYNVIQ 144 Query: 124 LA-LPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 +P + + G +I +SS+ G +G V Y A K + TKALA++ + + VNC Sbjct: 145 PCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNC 204 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240 I+PG I T + E + ++E M P+ RMGQ EV A +L S+ A + T Sbjct: 205 IAPGLIDTGMIEM-------EESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTR 257 Query: 241 IELLVTGGA 249 + + GG Sbjct: 258 QVISINGGM 266 >5VT6-A nrPDB Length = 269 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 118/255 (46%), Gaps = 13/255 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL-----EQELPGAVF 58 G+ A +V VTGG G+GA I R ++G V + + + + Sbjct: 20 GSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKA 79 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 DV + + + + FG++D ++NNAG + T + ++ +L Sbjct: 80 YAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKG-DWDAVMRTDLDAM 138 Query: 119 YTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + +TK + + + + G ++NI S+ G+ G Y + K + TK LAL+ + G+ Sbjct: 139 FNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGI 198 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EAN 236 VN +SPG + T + E + + + + + P+GR+G+P EV A FL S +A Sbjct: 199 TVNTVSPGYLATAMVEAVPQDVLE-----AKILPQIPVGRLGRPDEVAALIAFLCSDDAG 253 Query: 237 FCTGIELLVTGGAEL 251 F TG +L + GG + Sbjct: 254 FVTGADLAINGGMHM 268 >3WYE-A nrPDB Length = 256 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 119/252 (47%), Gaps = 13/252 (5%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILCDVTQ 65 KV +VTG G+GIG I V G V I D +++ +A+ E+ AV + DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 D V V + + G D +VNNAG + E + + +Q+ +N+ + + A Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGIA-QIKPLLEVTEEDLKQIYSVNVFSVFFGIQAA 121 Query: 126 LPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + +K G +IN +S+ G Y TK AV +T+ A D +P G+ VN Sbjct: 122 VEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 184 PGNIWTPLWEELAALMPDPRA-----TIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANF 237 PG + T +WE++ A + +E + LGR P +V FLAS ++++ Sbjct: 182 PGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSDY 241 Query: 238 CTGIELLVTGGA 249 TG LL+ GG Sbjct: 242 MTGQSLLIDGGM 253 >1X1T-A nrPDB Length = 260 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 82/258 (31%), Positives = 122/258 (47%), Gaps = 15/258 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA------LEQELPGAVFIL 60 GKV VVTG GIG GI A GA +V+ ++ Q ++ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 D+++ + V+ LV +R+ GR+D +VNNAG E+ + + +L LNL + Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTA-LIEDFPTEKWDAILALNLSAVFH 120 Query: 121 LTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 T ALP+++K G +INI+S G + A YVA K V TK AL+ + G+ Sbjct: 121 GTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITA 180 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLA------QPLGRMGQPAEVGAAAVFLAS 233 N I PG + TPL E+ + + + +E QP + P ++G AVFLAS Sbjct: 181 NAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLAS 240 Query: 234 EANF-CTGIELLVTGGAE 250 +A TG + V GG Sbjct: 241 DAAAQITGTTVSVDGGWT 258 >1O5I-A nrPDB Length = 249 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 66/252 (26%), Positives = 116/252 (46%), Gaps = 21/252 (8%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 M G R G V+V RGIG + GA V IC ++E + G +++ Sbjct: 13 MELGIRDKG--VLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKR-----SGHRYVV 65 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 CD+ ++ D+ L + +D +V NAG P +E + + F++ ++ L Sbjct: 66 CDLRKDLDL--LFEKVKE----VDILVLNAGG-PKAGFFDELTNEDFKEAIDSLFLNMIK 118 Query: 121 LTKLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + + LP ++ K G ++ I+S + + A+T K L+ + +PYG+ V Sbjct: 119 IVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITV 178 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238 NC++PG T +EL + ++ P+ RM +P E+ + FL SE A++ Sbjct: 179 NCVAPGWTETERVKELLS-----EEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYL 233 Query: 239 TGIELLVTGGAE 250 TG ++V GG Sbjct: 234 TGQTIVVDGGLS 245 >3UVE-A nrPDB Length = 286 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 68/279 (24%), Positives = 114/279 (40%), Gaps = 34/279 (12%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK--------------------DESG 45 R GKV VTG RG G GA ++ D Sbjct: 8 RVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAET 67 Query: 46 GRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQ 105 ++ V DV D +K V + + GRLD +V NAG ++TS + Sbjct: 68 ADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEE 127 Query: 106 GFRQLLELNLLGTYTLTKLALPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTA 163 + +++++NL G + K +P++ G++I SS+ G YVA K V Sbjct: 128 DWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVG 187 Query: 164 MTKALALDESPYGVRVNCISPGNIWTPLWE----------ELAALMPDPRATIREGMLAQ 213 + +A ++ + +RVN + P ++ TP+ +L PD A I + Sbjct: 188 LMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTL 247 Query: 214 PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAEL 251 P+ +P ++ A +F AS+ A + TG+ L + G+ L Sbjct: 248 PIP-WVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >4Z9Y-A nrPDB Length = 253 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 67/248 (27%), Positives = 116/248 (46%), Gaps = 10/248 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI--LCDVT 64 GKV ++TG G+G G+ +G +V + E + G F+ D++ Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADMS 67 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 LV + + FG +D +VNNAG E S + + ++ LN+ + +++ Sbjct: 68 NVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAI-EFSEKNWDDVMNLNIKSVFFMSQT 126 Query: 125 ALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 K G +INI+S++ G + Y A+K AV +T+ +A + + +G+ VN I Sbjct: 127 VARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNAI 186 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEAN-FCTGI 241 +PG + T ++L A +E + P GR G P ++ +VFLAS A+ + G Sbjct: 187 APGYMATNNTQQLRA----DEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYINGY 242 Query: 242 ELLVTGGA 249 + V GG Sbjct: 243 TIAVDGGW 250 >1K2W-A nrPDB Length = 256 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 80/256 (31%), Positives = 125/256 (48%), Gaps = 10/256 (3%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDV 63 R GK ++TG RGIG A+V GARV I D + RA E+ P A I DV Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDV 60 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 T + + V+E + R+G +D +VNNA E + + + +L +N+ GT + + Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAP-IVEITRESYDRLFAINVSGTLFMMQ 119 Query: 124 LALPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + G +IN++S G G+A Y ATK AV ++T++ L+ +G+ VN Sbjct: 120 AVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNA 179 Query: 182 ISPGNIWTPLWEELAALMPDPR-----ATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EA 235 I+PG + W+ + A D R+ A P GRMG+ ++ A+FLA+ EA Sbjct: 180 IAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEA 239 Query: 236 NFCTGIELLVTGGAEL 251 ++ V GG + Sbjct: 240 DYIVAQTYNVDGGNWM 255 >3W8F-A nrPDB Length = 260 Score = 203 bits (518), Expect = 4e-53, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 112/258 (43%), Gaps = 15/258 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVIC------DKDESGGRALEQELPGAVFIL 60 GK VVTG GIG + +GA VVI D + + A ++ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 D++ + +++ G LD +VNNAG EE + ++ LNL + Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAP-IEEFPVDKWNAIIALNLSAVFH 120 Query: 121 LTKLALPYL-RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 T ALP + ++ G +INI+S G + YVA K V +TK AL+ + G+ Sbjct: 121 GTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITC 180 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLA------QPLGRMGQPAEVGAAAVFLAS 233 N I PG + TPL E+ + + E QP + P ++G AAVFL+S Sbjct: 181 NAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS 240 Query: 234 -EANFCTGIELLVTGGAE 250 A+ TG L + GG Sbjct: 241 AAADQMTGTTLSLDGGWT 258 >1UZM-A nrPDB Length = 247 Score = 203 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 16/249 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + + V+VTGG RGIG I + G +V + + + G + DVT Sbjct: 13 FVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPK-------GLFGVEVDVTDS 65 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 D V + G ++ +V+NAG + + F +++ NL G + + + A Sbjct: 66 DAVDRAFTAVEEHQGPVEVLVSNAGLS-ADAFLMRMTEEKFEKVINANLTGAFRVAQRAS 124 Query: 127 PYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 +++++ G +I I S+ G G Y A+K V M +++A + S V N ++PG Sbjct: 125 RSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPG 184 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELL 244 I T + L + + P R+G PAEV FLAS +A++ +G + Sbjct: 185 YIDTDMTRALD------ERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIP 238 Query: 245 VTGGAELGY 253 V GG +G+ Sbjct: 239 VDGGMGMGH 247 >4DBZ-A nrPDB Length = 281 Score = 203 bits (517), Expect = 7e-53, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 116/255 (45%), Gaps = 14/255 (5%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF----ILCDV 63 +V +VTG GIG I R G RV +C + E G R +EL A CDV Sbjct: 25 DSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDV 84 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 +++ LV+ + R+G +D +VNNAG P E + + + ++E NL G + +TK Sbjct: 85 RSVPEIEALVAAVVERYGPVDVLVNNAGR-PGGGATAELADELWLDVVETNLTGVFRVTK 143 Query: 124 LALP---YLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 L L + G ++NI+S G G A PY A+K V TKAL L+ + G+ VN Sbjct: 144 QVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVN 203 Query: 181 CISPGNIWTPLWEELAALMPDP-----RATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 + PG + TP+ + D P+GR QP+EV +L Sbjct: 204 AVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPG 263 Query: 235 ANFCTGIELLVTGGA 249 A T L V GG Sbjct: 264 AAAVTAQALNVCGGL 278 >5YSS-A nrPDB Length = 256 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 68/254 (26%), Positives = 117/254 (46%), Gaps = 10/254 (3%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE--SGGRALEQELPGAVFILCD 62 GK +VTG GIG GI + +GA +++ + + A+ Q + D Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGAD 60 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 ++ E + ++ FG +D ++NNAG E + ++ +NL + T Sbjct: 61 LSDEAQIADMMRYAESEFGGVDILINNAGIQH-VSPIETFPVDKWNAIIAINLSSVFHTT 119 Query: 123 KLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 +LALP +R ++ G +INI+S+ G + + YVA K V +TK +AL+ + + N Sbjct: 120 RLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNA 179 Query: 182 ISPGNIWTPLWEEL----AALMPDPRATIREGML-AQPLGRMGQPAEVGAAAVFLASE-A 235 + PG + TPL ++ A +P A + QP P ++G A+FL S+ A Sbjct: 180 LCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGA 239 Query: 236 NFCTGIELLVTGGA 249 G+ + GG Sbjct: 240 AQVRGVAWNMDGGW 253 >3V2H-A nrPDB Length = 281 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 120/258 (46%), Gaps = 15/258 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE-SGGRALEQELPG-----AVFIL 60 K V+TG GIG I R +GA +V+ R + E+ G + Sbjct: 23 MMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHP 82 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 D+T+ ++ +++ RFG D +VNNAG ++ E+ + + +++ +NL ++ Sbjct: 83 ADMTKPSEIADMMAMVADRFGGADILVNNAGVQF-VEKIEDFPVEQWDRIIAVNLSSSFH 141 Query: 121 LTKLALPYLRK-SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + A+P ++K G +INI+S G + YVA K + +TK +AL+ + GV V Sbjct: 142 TIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTV 201 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLA------QPLGRMGQPAEVGAAAVFLA- 232 N I PG + TPL E+ R E ++ QP + +V + A++LA Sbjct: 202 NSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAG 261 Query: 233 SEANFCTGIELLVTGGAE 250 +A TG + + GG Sbjct: 262 DDAAQITGTHVSMDGGWT 279 >3T7C-A nrPDB Length = 299 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 67/275 (24%), Positives = 117/275 (42%), Gaps = 30/275 (10%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK----------------DESGGRAL 49 + GKV +TG RG G GA ++ D R + Sbjct: 25 KVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQV 84 Query: 50 EQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 E + DV D ++ V + + + GRLD V+ NA R + +R Sbjct: 85 EALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRD 144 Query: 110 LLELNLLGTYTLTKLALPYLR--KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA 167 ++++NL G + ++A+P++ K G+++ SS+ G G Y+A+K + + + Sbjct: 145 MIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRT 204 Query: 168 LALDESPYGVRVNCISPGNIWTPL----------WEELAALMPDPRATIREGMLAQPLGR 217 +AL+ P +RVN + P ++ TP+ +L + M P+ Sbjct: 205 MALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIP- 263 Query: 218 MGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 251 +PA++ A +FL S +A + TG+ L V GGA L Sbjct: 264 YVEPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >2HSD-A nrPDB Length = 253 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 134/255 (52%), Gaps = 10/255 (3%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-GAVFILCDV 63 +GK V++TGG RG+GA R V +GARVV+ D + G A +EL A + DV Sbjct: 1 NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDV 60 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 T E+D + +V+ FG +D +VNNAG E S + FR+++E+NL G + K Sbjct: 61 TIEEDWQRVVAYAREEFGSVDGLVNNAGIST-GMFLETESVERFRKVVEINLTGVFIGMK 119 Query: 124 LALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 +P ++ G+++NISS G +G A Y A+K V ++K A++ +RVN + Sbjct: 120 TVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSV 179 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGI 241 PG +TP+ E + P+GR+G+P E+ A V L S+ +++ TG Sbjct: 180 HPGMTYTPMTAETGIRQGEGNYP------NTPMGRVGEPGEIAGAVVKLLSDTSSYVTGA 233 Query: 242 ELLVTGGAELGYGCK 256 EL V GG G K Sbjct: 234 ELAVDGGWTTGPTVK 248 >3WTC-A nrPDB Length = 262 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 13/259 (5%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG----AVF 58 + +GK+ VTG +GIG I GA V++ D + +E+ AV Sbjct: 2 SHMSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVA 61 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 + D++ D ++ +++ + G LD +VNNAG + + ++ +N+ G Sbjct: 62 LTADISNRDQFRSTLADAAKTLGGLDIMVNNAGIC-QVKPILDIEPAEIEKIFSINVQGV 120 Query: 119 YTLTKLALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + A ++ G +IN S+ G G Y ATK AV A+T++ A + + G Sbjct: 121 LWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSG 180 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPR-----ATIREGMLAQPLGRMGQPAEVGAAAVFL 231 + VN PG + T +W + M + AT ++ + LGR+ +V +L Sbjct: 181 ITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYL 240 Query: 232 -ASEANFCTGIELLVTGGA 249 +S+A++ TG +L+ GG Sbjct: 241 SSSDADYMTGQSVLIDGGL 259 >4MOW-A nrPDB Length = 256 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 89/252 (35%), Positives = 137/252 (54%), Gaps = 11/252 (4%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR-----ALEQELPGAVFI 59 ++ AGKV +VTG +GIGA I +A + GA VV+ G A+ + AV + Sbjct: 10 SKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAV 69 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 DV++ D + +V I +GRLD +VNN+G + E + + +R+ + N+ G Sbjct: 70 GGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVY-EFAPIEAITEEHYRRQFDTNVFGVL 128 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 T+ A+ +L ++INISS+V +I + Y TKGAV A+T LAL+ P +RV Sbjct: 129 LTTQAAVKHL-GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRV 187 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFC 238 N I+PG I T + D A + + PLGR+G+P ++ + AVFLAS +A + Sbjct: 188 NAINPGMIVTEGTHSAGIIGSDLEAQV---LGQTPLGRLGEPNDIASVAVFLASDDARWM 244 Query: 239 TGIELLVTGGAE 250 TG L+V+GG Sbjct: 245 TGEHLVVSGGLN 256 >4AVY-A nrPDB Length = 242 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 90/246 (36%), Positives = 119/246 (48%), Gaps = 14/246 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 YAG+ V+VTGG GIGA I F GA VV D G A P D+T Sbjct: 9 YAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRH--PRIRREELDITDS 66 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 ++ L RLD +VNNAG EE F ++L LNL ++LA Sbjct: 67 QRLQRLFEA----LPRLDVLVNNAGISRD---REEYDLATFERVLRLNLSAAMLASQLAR 119 Query: 127 PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186 P L + G+++NI+S+ G A Y A+KGA+ +T++LA + + +RVN I+PG Sbjct: 120 PLLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGW 179 Query: 187 IWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLV 245 I TPL L A + R M PL R G+ EV +AA FL A+F TG L V Sbjct: 180 IDTPLGAGLKADV----EATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAV 235 Query: 246 TGGAEL 251 GG Sbjct: 236 DGGYLC 241 >4RZI-B nrPDB Length = 240 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 78/247 (31%), Positives = 117/247 (47%), Gaps = 16/247 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 KV+VVTGG RGIGA IV+ GA+V D GG A+ ++ +VT Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT------EALGVVANVTDL 59 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + + +E + G + VV NAG P+ + + +L +NL G K + Sbjct: 60 ESMTAAAAEITDKLGPVYGVVANAGITKDNFFPK-LTPADWDAVLNVNLKGVAYSIKPFI 118 Query: 127 PYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 + + + G+++ ISS+ G G Y ATK V M K+LA + + YGVR N ++PG Sbjct: 119 EGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPG 178 Query: 186 NIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS--EANFCTGIEL 243 I T + A+ D R I + + P R G+P E+ A FL S +++ TG L Sbjct: 179 FIDTEMT---LAIREDIREKITKEI---PFRRFGKPEEIAWAVAFLLSPVASSYVTGEVL 232 Query: 244 LVTGGAE 250 V G Sbjct: 233 RVNGAHH 239 >1DOH-A nrPDB Length = 283 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 61/259 (23%), Positives = 118/259 (45%), Gaps = 16/259 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD-----ESGGRALEQELPGAVFILC 61 GKV +VTG GRGIG + G +V++ + E A+++ A + Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKA 86 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 +V +D+ + E ++ FG+LD V +N+G ++ + + F ++ +N G + + Sbjct: 87 NVGVVEDIVRMFEEAVKIFGKLDIVCSNSGV-VSFGHVKDVTPEEFDRVFTINTRGQFFV 145 Query: 122 TKLALPYLRKSQGNVINISSLVGA-IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + A +L G +I + S+ G + Y +KGA+ + +A+D + + VN Sbjct: 146 AREAYKHLEI-GGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITVN 204 Query: 181 CISPGNIWTPLWEEL-------AALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 ++PG I T ++ + + + + PL R+G P ++ FLAS Sbjct: 205 VVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLAS 264 Query: 234 -EANFCTGIELLVTGGAEL 251 + + TG + + GGA + Sbjct: 265 NDGGWVTGKVIGIDGGACM 283 >1AHH-A nrPDB Length = 255 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 121/249 (48%), Gaps = 13/249 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILC 61 R GK ++TG G GIG I F +GA VV+ D + + E+ A C Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 D+T E ++ L I + G++D +VNNAG P + FR+ ELN+ + L Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF--DMPMADFRRAYELNVFSFFHL 125 Query: 122 TKLALPYLRKSQGNVI-NISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 ++L P + K+ G VI I+S+ Y ++K A + + + +A D +RVN Sbjct: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCT 239 I+PG I T + + ++ + P+ R+GQP ++ AA+FL S A++ + Sbjct: 186 GIAPGAILTDALKSVITP-----EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 Query: 240 GIELLVTGG 248 G L V+GG Sbjct: 241 GQILTVSGG 249 >4FC7-A nrPDB Length = 277 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 126/254 (49%), Gaps = 11/254 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC----- 61 KV +TGGG GIG I F+ G VI + ++L GA C Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 84 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DV V V + ++ FGR+D ++N A + S F+ +++++ GT+ + Sbjct: 85 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP-AGALSFNAFKTVMDIDTSGTFNV 143 Query: 122 TKLAL-PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 +++ + R G ++NI++ +G GQA V + K AV AMT+ LA++ P +RVN Sbjct: 144 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 203 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCT 239 ++PG I E + P+A++ + A PL R+G E+ + ++LAS A++ T Sbjct: 204 SLAPGPIS---GTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVT 260 Query: 240 GIELLVTGGAELGY 253 G L+ GGA L + Sbjct: 261 GAVLVADGGAWLTF 274 >3D3W-A nrPDB Length = 244 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 72/247 (29%), Positives = 119/247 (48%), Gaps = 12/247 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 AG+ V+VTG G+GIG G V+A +GARVV + ++ +L +E PG + D+ Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDW 64 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + + + G +D +VNNA Q E + + F + E+NL ++++ Sbjct: 65 EATERALGSV----GPVDLLVNNAAVA-LLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVA 119 Query: 127 PYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 L G ++N+SS Y +TKGA+ +TK +AL+ P+ +RVN ++P Sbjct: 120 RGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNP 179 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIEL 243 + T + + A DP + + PLG+ + V A +FL S+ + TG L Sbjct: 180 TVVMTSMGQ---ATWSDPHKA-KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTL 235 Query: 244 LVTGGAE 250 V GG Sbjct: 236 PVEGGFW 242 >3RWB-A nrPDB Length = 247 Score = 197 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 112/248 (45%), Gaps = 10/248 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVT 64 R AGK +VTG +GIG I GA V++ D + G +A + A I D++ Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADIS 62 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 VK L +E G +D +VNNA P ++ +R+++++NL GT+ +T+ Sbjct: 63 DPGSVKALFAEIQALTGGIDILVNNASIVPFVAW-DDVDLDHWRKIIDVNLTGTFIVTRA 121 Query: 125 ALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 +R + G VI+I+S G YVA KG V T+ALA + Y + N + Sbjct: 122 GTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAV 181 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 +PG I + + + Q + GQP + FLAS +A + TG Sbjct: 182 TPGLIESDGVKASP-----HNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARWITGQ 236 Query: 242 ELLVTGGA 249 L V G Sbjct: 237 TLNVDAGM 244 >3V2G-A nrPDB Length = 271 Score = 197 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 74/257 (28%), Positives = 110/257 (42%), Gaps = 16/257 (6%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-----KDESGGRALEQELPG 55 M T AGK VTGG RGIGA I + GA V + + ++ +EQ Sbjct: 23 MMTSISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGR 82 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 AV I D + ++ + ET+ G LD +VN+AG EET+ F +++ +N Sbjct: 83 AVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPL-EETTVADFDEVMAVNF 141 Query: 116 LGTYTLTKLALPYLRKSQGNVINISS-LVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 + + A +L G +I I S L + Y A+K A+ +TK LA D P Sbjct: 142 RAPFVAIRSASRHL-GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGP 200 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS- 233 G+ VN + PG+ T + P G G+P ++ +LA Sbjct: 201 RGITVNIVHPGSTDTDMN-------PADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGP 253 Query: 234 EANFCTGIELLVTGGAE 250 + F TG L + GGA Sbjct: 254 QGKFVTGASLTIDGGAN 270 >4E6P-A nrPDB Length = 259 Score = 197 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 79/256 (30%), Positives = 121/256 (47%), Gaps = 10/256 (3%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-PGAVFILCDV 63 R GK ++TG RGIG A+V GA V I D D R E+ P A + DV Sbjct: 4 KRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDV 63 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 T++D + ++ T+ G LD +VNNA E + + + +L +N+ GT + Sbjct: 64 TRQDSIDAAIAATVEHAGGLDILVNNAALFDLAP-IVEITRESYEKLFAINVAGTLFTLQ 122 Query: 124 LALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 A + + G +IN++S G G+A Y ATK AV ++T++ LD + + VN Sbjct: 123 AAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNA 182 Query: 182 ISPGNIWTPLWEELAALMPDPR-----ATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EA 235 I+PG + W+ + AL R A P GRMG ++ A+FLAS E+ Sbjct: 183 IAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAES 242 Query: 236 NFCTGIELLVTGGAEL 251 ++ V GG + Sbjct: 243 DYIVSQTYNVDGGNWM 258 >2P91-A nrPDB Length = 285 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 62/254 (24%), Positives = 109/254 (42%), Gaps = 13/254 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICD---KDESGGRALEQELPGAVFILC 61 GK ++TG R I GI ++F GA++ K E R + + + + C Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKC 78 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQR---PEETSAQGFRQLLELNLLGT 118 DV+ ++D+K L +G LD +V++ + P + +TS +GF+ +++++ Sbjct: 79 DVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYSL 138 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 LT+ LP + G ++ +S K A+ + + LA D + +G R Sbjct: 139 IALTRELLPLMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHGHR 198 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 +N IS G + T A + + P G+ +VG AVFL S+ A Sbjct: 199 INAISAGPVKT----LAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARA 254 Query: 238 CTGIELLVTGGAEL 251 TG + V G + Sbjct: 255 ITGEVVHVDNGYHI 268 >4IS3-A nrPDB Length = 268 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 66/251 (26%), Positives = 118/251 (47%), Gaps = 15/251 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL------PGAVF 58 KV ++TGG RGIG + F+++GA+V I + + +L + Sbjct: 21 NLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLG 80 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 D+T D V V + +++GRLD ++NNAG S + F+ ++++N+ G Sbjct: 81 FAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGI-TSNNVFSRVSEEEFKHIMDINVTGV 139 Query: 119 YTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + A ++ ++ G +IN +S+ G G V Y A+K +V +T L + + Sbjct: 140 FNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNI 199 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 RV ++PG + T + +P + + A P+ RM +P E+ +FLAS+ A+ Sbjct: 200 RVVGVAPGVVNTDMTN------GNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASDLAS 253 Query: 237 FCTGIELLVTG 247 T + V G Sbjct: 254 GITATTVSVDG 264 >2AG5-A nrPDB Length = 246 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 77/250 (30%), Positives = 122/250 (48%), Gaps = 9/250 (3%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R GKV+++T +GIG AF GA+V+ D +ES + LE+ PG + DVT+ Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK-YPGIQTRVLDVTK 61 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + + +E RLD + N AG + + + + LN+ Y + K Sbjct: 62 KKQIDQFANEVE----RLDVLFNVAGF-VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAF 116 Query: 126 LP-YLRKSQGNVINISSLVGAI-GQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 LP L + GN+IN+SS+ ++ G Y TK AV +TK++A D G+R NC+ Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242 PG + TP +E +P + + Q GR E+ V+LAS+ + + TG Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 Query: 243 LLVTGGAELG 252 +++ GG LG Sbjct: 237 VIIDGGWSLG 246 >1CYD-A nrPDB Length = 244 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 69/246 (28%), Positives = 126/246 (51%), Gaps = 12/246 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 ++G +VTG G+GIG V+A SGA+VV + S +L +E PG + D+ Sbjct: 5 FSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDW 64 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 D + + G +D +VNNA Q E + + F + +NL + ++++ Sbjct: 65 DATEKALGGI----GPVDLLVNNAAL-VIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVA 119 Query: 127 PYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 + G+++N+SS+V + + Y +TKGA+T +TKA+A++ P+ +RVN ++P Sbjct: 120 RDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNP 179 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCT-GIEL 243 + T + ++++A DP R+ PL + + +V + +FL S+ + T G + Sbjct: 180 TVVLTDMGKKVSA---DPEFA-RKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGI 235 Query: 244 LVTGGA 249 LV G Sbjct: 236 LVDAGY 241 >5EJ2-A nrPDB Length = 308 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 64/275 (23%), Positives = 115/275 (41%), Gaps = 30/275 (10%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK----------------DESGGRAL 49 R AGKV ++G RG G GA ++ D + Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 50 EQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 + V DV + +K+ V + + GRLD +V NAG ++ + ++ Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQD 153 Query: 110 LLELNLLGTYTLTKLALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA 167 ++++NL G + K +P++ G+++ SS+ G Y+A K V + +A Sbjct: 154 MIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRA 213 Query: 168 LALDESPYGVRVNCISPGNIWTPL----------WEELAALMPDPRATIREGMLAQPLGR 217 A++ P+ +RVN + P + T + +L PD A I + M P+ Sbjct: 214 FAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP- 272 Query: 218 MGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAEL 251 +++ A +FLAS+ + + TG+ L V G+ L Sbjct: 273 WVDASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >3OIC-A nrPDB Length = 258 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 64/253 (25%), Positives = 104/253 (41%), Gaps = 16/253 (6%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE-----SGGRALEQELPGAVFILCD 62 K +VTG RG+G +G +VI +E+ + + + Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNA--GHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 V Q +K + + FGRLD VNNA G P EET + + +N Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETH---WDWTMNINAKALLF 119 Query: 121 LTKLALPYLRKSQGN-VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + A + K+ G +++ISSL +K A+ A+T+ LA++ SP + V Sbjct: 120 CAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIV 179 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-SEANFC 238 N +S G I T + P+ + + P GRM + ++ FL S+A+ Sbjct: 180 NAVSGGAIDTDALKHF----PNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMI 235 Query: 239 TGIELLVTGGAEL 251 G ++V GG L Sbjct: 236 RGQTIIVDGGRSL 248 >4HP8-A nrPDB Length = 247 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 71/254 (27%), Positives = 109/254 (42%), Gaps = 15/254 (5%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD--ESGGRALEQELPGAVF 58 M G+ +VTG G+G I +GA VV + + + ++ A Sbjct: 1 MKNPFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASA 60 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 +L D K ++ D +VNNAG E S + +++++NL Sbjct: 61 LLIDFADPLAAKDSFTDA-----GFDILVNNAGIIRRADSV-EFSELDWDEVMDVNLKAL 114 Query: 119 YTLTKLALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + T+ L + G V+NI+SL+ G + Y A K V +TK LA + + G Sbjct: 115 FFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKG 174 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EA 235 + VN I+PG I T E L A +A + P GR G ++ AAVFL+S A Sbjct: 175 INVNAIAPGYIETNNTEALRADAARNKAILE----RIPAGRWGHSEDIAGAAVFLSSAAA 230 Query: 236 NFCTGIELLVTGGA 249 ++ G L V GG Sbjct: 231 DYVHGAILNVDGGW 244 >2B4Q-A nrPDB Length = 276 Score = 193 bits (492), Expect = 4e-50, Method: Composition-based stats. Identities = 77/261 (29%), Positives = 121/261 (46%), Gaps = 15/261 (5%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL---PGAV 57 M AG++ +VTGG RGIG I + + +GARV IC +D L Sbjct: 21 MHPYFSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQ 80 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 I D++ E + L RLD +VNNAG E G+ ++++LN+ Sbjct: 81 AIPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAA-LESYPVSGWEKVMQLNVTS 139 Query: 118 TYTLTKLALPYLRKSQ-----GNVINISSLVGAIGQAQA-VPYVATKGAVTAMTKALALD 171 ++ + LP LR+S VINI S+ G + Y +K A+ +++ LA + Sbjct: 140 VFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKE 199 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFL 231 + VN I+PG + + +A DP+A + + P+GR G+P E+ A A+ L Sbjct: 200 LVGEHINVNVIAPGRFPSRMTRHIAN---DPQA-LEADSASIPMGRWGRPEEMAALAISL 255 Query: 232 ASEAN-FCTGIELLVTGGAEL 251 A A + TG + + GG L Sbjct: 256 AGTAGAYMTGNVIPIDGGFHL 276 >5JY1-A nrPDB Length = 274 Score = 193 bits (491), Expect = 7e-50, Method: Composition-based stats. Identities = 85/264 (32%), Positives = 128/264 (48%), Gaps = 12/264 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILCD 62 +V +VTG G GIG G+ R+F N GA V+I + +ES GR +EQE+ ++F+ D Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 VT + ++ V + +FG LD +VNNA P EE + + Q L +L T+ Sbjct: 72 VTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAM 131 Query: 123 KLA-LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + A +P + G ++N S+ G Y K + +T++ A + + + VN Sbjct: 132 RAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNA 191 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPA-EVGAAAVFLASE-ANFCT 239 I+P T + L A+PLGR G P ++G AAVF ASE + F T Sbjct: 192 IAP----TAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVT 247 Query: 240 GIELLVTGGAEL-GYGCKASRSTP 262 G L V GG L GY + + P Sbjct: 248 GETLHVDGGLHLPGYNSRPAGIKP 271 >1HXH-A nrPDB Length = 253 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 78/250 (31%), Positives = 130/250 (52%), Gaps = 14/250 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDV 63 R GKV +VTGG G+G +V+ + GA+V D +E+ G+ L EL ++F+ DV Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDV 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + E D +++ RR G L+ +VNNAG P E + F +LL++N + + Sbjct: 62 SSEADWTLVMAAVQRRLGTLNVLVNNAGIL-LPGDMETGRLEDFSRLLKINTESVFIGCQ 120 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG--VRVNC 181 + ++++ G++IN++S+ + Q Y A+K AV+A+T+A AL G +RVN Sbjct: 121 QGIAAMKETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNS 180 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQP----LGRMGQPAEVGAAAVFLASE-AN 236 I P I+TP+ + P+ +E +L P GR P + +FLAS+ ++ Sbjct: 181 IHPDGIYTPMMQASL-----PKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDESS 235 Query: 237 FCTGIELLVT 246 +G EL Sbjct: 236 VMSGSELHAD 245 >2FWM-X nrPDB Length = 250 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 121/256 (47%), Gaps = 13/256 (5%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCD 62 ++GK V VTG G+GIG AFV +GA+V D +A QE + D Sbjct: 1 GHMDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD------QAFTQEQYPFATEVMD 54 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V V + + RLD +VN AG ++ S + ++Q +N+ G + L Sbjct: 55 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGAT-DQLSKEDWQQTFAVNVGGAFNLF 113 Query: 123 KLALPYLRKSQGN-VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + + R+ +G ++ ++S + Y A+K A+ ++ ++ L+ + GVR N Sbjct: 114 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 173 Query: 182 ISPGNIWTPLWEELAALMPDPRATIR----EGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 +SPG+ T + L IR + L PLG++ +P E+ +FLAS+ A+ Sbjct: 174 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 233 Query: 237 FCTGIELLVTGGAELG 252 T +++V GG+ LG Sbjct: 234 HITLQDIVVDGGSTLG 249 >3A28-C nrPDB Length = 258 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 116/255 (45%), Gaps = 15/255 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA------LEQELPGAVFILCD 62 KV +VTGG +GIG GI G + + D + +A +E AVF+ D Sbjct: 2 SKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLD 61 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 VT + + + + E + G D +VNNAG + E + + +Q+ +N+ + Sbjct: 62 VTDKANFDSAIDEAAEKLGGFDVLVNNAGIA-QIKPLLEVTEEDLKQIYSVNVFSVFFGI 120 Query: 123 KLALPYLR--KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + A +G +IN +S+ G Y TK AV +T+A A + +P G VN Sbjct: 121 QAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVN 180 Query: 181 CISPGNIWTPLWEELAALMPDPRA-----TIREGMLAQPLGRMGQPAEVGAAAVFLASEA 235 +PG + T +WE++ A + +E + LGR P +V FLASE Sbjct: 181 AYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASEN 240 Query: 236 N-FCTGIELLVTGGA 249 + + TG +LV GG Sbjct: 241 SNYVTGQVMLVDGGM 255 >5TF4-A nrPDB Length = 274 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 74/279 (26%), Positives = 119/279 (42%), Gaps = 21/279 (7%) Query: 1 MATGT-RYAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRA---LEQELP 54 MA G GK ++ G R I GI + ++GA + + E+ + L +E+ Sbjct: 3 MAKGNGLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVK 62 Query: 55 GAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPP---PQRPEETSAQGFRQLL 111 G V CDV+ + + + +++G+LD +V+ G R + S F + Sbjct: 63 GFVCGHCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTM 122 Query: 112 ELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD 171 +++ LTK A + G+++ ++ K A+ A K LA+D Sbjct: 123 NISVYSLTALTKRAEKLM-SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVD 181 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFL 231 P +RVN IS G I T A+ + D R ++ PL R EVG +A++L Sbjct: 182 LGPKHIRVNAISAGPIKT----LAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYL 237 Query: 232 ASE-ANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIP 269 S+ + TG V G + G KA VDAPDI Sbjct: 238 LSDLSRSVTGEVHHVDSGYNI-IGMKA-----VDAPDIS 270 >2CFC-A nrPDB Length = 250 Score = 190 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 66/248 (26%), Positives = 113/248 (45%), Gaps = 13/248 (5%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE-----LPGAVFILCDV 63 +V +VTG G G I F+ G RV D + + + DV Sbjct: 2 SRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADV 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHP--PPQRPEETSAQGFRQLLELNLLGTYTL 121 E DV ++ T+ +FG +D +VNNAG T + F +++ +N+ G + Sbjct: 62 ADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLG 121 Query: 122 TKLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN 180 + LP++ + G ++NI+S+ + Y +KGAV +TK++A+D + G+R N Sbjct: 122 CRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCN 181 Query: 181 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCT 239 + PG I TP+ + D + + P +G A+V A +FLA +A + Sbjct: 182 AVCPGMIETPMTQ----WRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVN 237 Query: 240 GIELLVTG 247 G L++ G Sbjct: 238 GAALVMDG 245 >5B1Y-A nrPDB Length = 270 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 80/255 (31%), Positives = 113/255 (44%), Gaps = 15/255 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL------PGAV 57 G+ +VTGG RGIG V F G VVI K + E P A Sbjct: 18 GSHMETTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAY 77 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 + DV D V + S L+ +VN AG EETS + + L +NL G Sbjct: 78 TVRVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGG-IEETSISEWEETLRVNLTG 136 Query: 118 TYTLTKLALPYLRKS-QGNVINISSLVGAIGQAQA-VPYVATKGAVTAMTKALALDESPY 175 Y +TKL LP LRK+ +++N++S+ G G A V Y A+K V +TK LA+ + Y Sbjct: 137 VYLVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGY 196 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 G+RVN ++P + T + D PL + +P +V A +FLA Sbjct: 197 GIRVNAVAPSFVETDMTRSFL----DTPEKRERIASLHPLKIILKPEDVAEAILFLADPR 252 Query: 235 -ANFCTGIELLVTGG 248 + TG L + G Sbjct: 253 RSRGITGHVLSINAG 267 >3V8B-A nrPDB Length = 283 Score = 187 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 71/252 (28%), Positives = 115/252 (45%), Gaps = 11/252 (4%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA----VFILCDVTQE 66 V ++TG G GIG A G V + + + E+ GA + + DV+ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 ++ V + + +FG LD VV NAG + ++ + + + +NL GT+ L + Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTV 149 Query: 127 PYLRKSQGN-VINISSLVGAIGQ--AQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 PYL++ G ++ +SS+ G A Y ATK A A+ + LAL+ + +RVN + Sbjct: 150 PYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNAVC 209 Query: 184 PGNIWTPLWEELAALMPDPRATIRE---GMLAQPLGRMGQPAEVGAAAVFLASE-ANFCT 239 PG I T + + + A E G + G+ G+ +V FL SE A T Sbjct: 210 PGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARHVT 269 Query: 240 GIELLVTGGAEL 251 G + + GG L Sbjct: 270 GSPVWIDGGQGL 281 >3U5T-A nrPDB Length = 267 Score = 186 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 72/247 (29%), Positives = 104/247 (42%), Gaps = 13/247 (5%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA-----LEQELPGAVFILCD 62 KV +VTG RGIGA I + G VVI ++ +E A+ D Sbjct: 26 TNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQAD 85 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 V+ V+ L + FG +D +VNNAG P ET F +++ +NL GT+ Sbjct: 86 VSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPL-TTIAETGDAVFDRVIAVNLKGTFNTL 144 Query: 123 KLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182 + A LR G +IN+S+ + Y A K V AMT L+ + + VN + Sbjct: 145 REAAQRLR-VGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDITVNAV 203 Query: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGI 241 +PG T L+ L PL R+G P ++ A FLA + + G Sbjct: 204 APGPTATDLF-----LEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNGQ 258 Query: 242 ELLVTGG 248 L GG Sbjct: 259 VLRANGG 265 >3K2E-A nrPDB Length = 296 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 69/278 (24%), Positives = 109/278 (39%), Gaps = 20/278 (7%) Query: 1 MATGTRYAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRA---LEQELPG 55 M TG GK V+ G + + GI +A GA V + E+ + L + L Sbjct: 22 MRTGMLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGV 81 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPP---QRPEETSAQGFRQLLE 112 + + CDV+ + V + +G LD VV+ R +TS F + Sbjct: 82 KLTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMH 141 Query: 113 LNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDE 172 ++ + A P + + G+++ +S K A+ A K LA+D Sbjct: 142 ISCYSFTYIASKAEPLMT-NGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDL 200 Query: 173 SPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA 232 +RVN IS G + T ++ + D + PL R +VG AA++L Sbjct: 201 GKQQIRVNAISAGPVRT----LASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLL 256 Query: 233 SE-ANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIP 269 S+ TG + V GY +S VDAPDI Sbjct: 257 SDLGRGTTGETVHVD----CGYHVVGMKS--VDAPDIS 288 >3ZV3-A nrPDB Length = 281 Score = 185 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 113/258 (43%), Gaps = 12/258 (4%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE-QELPGAVFILCDV 63 + G+V ++TGG G+G +V FV GARV + DK R LE AV ++ DV Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDV 60 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGH----HPPPQRPEETSAQGFRQLLELNLLGTY 119 D K + FG++D ++ NAG PE+ F + +N+ G Sbjct: 61 RSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYI 120 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 K LP L S+G+V+ S G Y ATK AV + + +A + +P+ VRV Sbjct: 121 HAVKACLPALVSSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH-VRV 179 Query: 180 NCISPGNIWTPLWEELAALMPDPRATIREGM----LAQPLGRMGQPAEVGAAAVFLASEA 235 N ++PG + T L + + + + P+GRM E A VF A+ Sbjct: 180 NGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFATRG 239 Query: 236 NFC--TGIELLVTGGAEL 251 + TG L GG + Sbjct: 240 DSLPATGALLNYDGGMGV 257 >3UN1-A nrPDB Length = 260 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 127/251 (50%), Gaps = 19/251 (7%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVT 64 R KVVV+TG +GIGAG+VRA+ + RVV + P + D++ Sbjct: 24 MRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSAD-----PDIHTVAGDIS 78 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-K 123 + + +V E I RFGR+D +VNNAG + E + + + L +N+ G + +T + Sbjct: 79 KPETADRIVREGIERFGRIDSLVNNAGVF-LAKPFVEMTQEDYDHNLGVNVAGFFHITQR 137 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVAT--KGAVTAMTKALALDESPYGVRVNC 181 A L++ G++++I++ + +A+ KG + A+T++LA++ S GVRVN Sbjct: 138 AAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNA 197 Query: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGI 241 +SPG I TP+ P T P+GRMG+ +V A ++L A F TG Sbjct: 198 VSPGVIKTPM---------HPAETHSTLAGLHPVGRMGEIRDVVDAVLYL-EHAGFITGE 247 Query: 242 ELLVTGGAELG 252 L V GG G Sbjct: 248 ILHVDGGQNAG 258 >3UF0-A nrPDB Length = 273 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 115/254 (45%), Gaps = 11/254 (4%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE---SGGRALEQELPGAV 57 M AG+ VVTG G GIG I + +GA V+ + + + A Sbjct: 23 MTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAE 82 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 ++ D+ + + E R+D +VNNAG EE S +R++L +NL Sbjct: 83 AVVADLADLEGAANVAEELAAT-RRVDVLVNNAGI-IARAPAEEVSLGRWREVLTVNLDA 140 Query: 118 TYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + L++ + G ++ I+S++ G Y A+K AV +T+ALA + + G Sbjct: 141 AWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRG 200 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-A 235 V VN ++PG + T L A D RA E P GR P ++ AVFLAS+ A Sbjct: 201 VGVNALAPGYVVTANTAALRA--DDERAA--EITARIPAGRWATPEDMVGPAVFLASDAA 256 Query: 236 NFCTGIELLVTGGA 249 ++ G L V GG Sbjct: 257 SYVHGQVLAVDGGW 270 >3GRK-A nrPDB Length = 293 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 66/272 (24%), Positives = 110/272 (40%), Gaps = 20/272 (7%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRA---LEQELPGAVFILC 61 GK ++ G R I GI +A +GA + + ++ + L +EL V C Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAGHC 88 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPP---QRPEETSAQGFRQLLELNLLGT 118 DV + + +++G+LD +V+ G R +TS F + +++ Sbjct: 89 DVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYSL 148 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 +++ A + G+++ ++ K A+ A K LA+D P +R Sbjct: 149 TAVSRRAEKLM-ADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIR 207 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VN IS G I T A+ + D R ++ PL R EVG ++ S+ + Sbjct: 208 VNAISAGPIKT----LAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLSRS 263 Query: 238 CTGIELLVTGGAELGYGCKASRSTPVDAPDIP 269 TG G + G KA VDAPDI Sbjct: 264 VTGEVHHADSGYHV-IGMKA-----VDAPDIS 289 >4GKB-A nrPDB Length = 258 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 87/249 (34%), Positives = 122/249 (48%), Gaps = 7/249 (2%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK---DESGGRALEQELPGAVFILCDV 63 KVV+VTGG GIG I A V+ + D + AL Q P A ++ ++ Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVEL 64 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + + V++TI FGRLD +VNNAG + + F LE NL+ Y + Sbjct: 65 QDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGL--DAGRDAFVASLERNLIHYYAMAH 122 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 +P+L+ ++G ++NISS GQ Y A+KGA A+T+ A+ +GVRVN + Sbjct: 123 YCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVI 182 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLG-RMGQPAEVGAAAVFLASE-ANFCTGI 241 P + TPL+ A DP A + E PLG R P E+ AVFL S A+ TG Sbjct: 183 PAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTGE 242 Query: 242 ELLVTGGAE 250 L V GG Sbjct: 243 WLFVDGGYT 251 >4M89-A nrPDB Length = 261 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 64/255 (25%), Positives = 101/255 (39%), Gaps = 14/255 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVIC---DKDESGGRALEQELPGAVFILC 61 GK +++TG R I GI +A GA + DK E R + EL + C Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVFRC 63 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPP----PQRPEETSAQGFRQLLELNLLG 117 DV +D++ + ++ + + LD +V++ G P + S + F E++ Sbjct: 64 DVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAYS 123 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 L K A P +R ++ +S L K ++ A + A G+ Sbjct: 124 LPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEGI 183 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 R N IS G I T A+ + D + PL R EVG A FL S+ ++ Sbjct: 184 RCNGISAGPIKT----LAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDLSS 239 Query: 237 FCTGIELLVTGGAEL 251 TG V GG + Sbjct: 240 GITGEITYVDGGYSI 254 >3U4C-A nrPDB Length = 281 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 51/259 (19%), Positives = 109/259 (42%), Gaps = 14/259 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL------PGAV 57 G+ + + V G +GIG I + +VI ++ ++++++ + Sbjct: 18 GSHMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVI 77 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 + D++ + + + + GRLD ++NN P + + + + Sbjct: 78 VLAGDMSDQHTRAGIFQKIESQCGRLDVLINNI-PGGAPDTFDNCNIEDMTATFTQKTVA 136 Query: 118 TYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 K A +++++ G +INI + A A+ +K +++ +P+ Sbjct: 137 YIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHN 196 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-----PLGRMGQPAEVGAAAVFL 231 + VNC++PG I T + + + + ++ Q P+ R+G E A A FL Sbjct: 197 ITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFL 256 Query: 232 AS-EANFCTGIELLVTGGA 249 AS EA++ TG ++ GG+ Sbjct: 257 ASEEASYITGQQISADGGS 275 >1BDB-A nrPDB Length = 277 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 84/278 (30%), Positives = 127/278 (45%), Gaps = 17/278 (6%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE-QELPGAVFILCDV 63 + G+ V++TGG G+G +V FV GA+V + DK LE + I+ DV Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDV 60 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGH----HPPPQRPEETSAQGFRQLLELNLLGTY 119 +D K S + RFG++D ++ NAG PEE+ F ++ +N+ G Sbjct: 61 RSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYI 120 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 K LP L S+GNVI S G Y A K A+ + + LA + +PY VRV Sbjct: 121 HAVKACLPALVASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-VRV 179 Query: 180 NCISPGNIWTPLWEELAALMPD------PRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 N + G I + L + M P A + + +L P+GRM + E A VF A+ Sbjct: 180 NGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVL--PIGRMPEVEEYTGAYVFFAT 237 Query: 234 --EANFCTGIELLVTGGAEL-GYGCKASRSTPVDAPDI 268 +A TG L GG + G+ A + ++ +I Sbjct: 238 RGDAAPATGALLNYDGGLGVRGFFSGAGGNDLLEQLNI 275 >2YW9-A nrPDB Length = 261 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 67/254 (26%), Positives = 103/254 (40%), Gaps = 14/254 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDES---GGRALEQELPGAVFILC 61 +GK +V G R +G I +GA V + + E L + L GA+ Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLFRA 65 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPP---QRPEETSAQGFRQLLELNLLGT 118 DVTQ++++ L + FG LD +V+ P R +T Q + LE++ Sbjct: 66 DVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYSL 125 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + A P LR+ G ++ ++ + K A+ A + LA + P GVR Sbjct: 126 VAVARRAEPLLREGGG-IVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVR 184 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VN IS G + T A +P PL R EVG +FL S A+ Sbjct: 185 VNAISAGPVRT----VAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASG 240 Query: 238 CTGIELLVTGGAEL 251 TG + V G + Sbjct: 241 ITGEVVYVDAGYHI 254 >1H5Q-A nrPDB Length = 265 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 120/268 (44%), Gaps = 24/268 (8%) Query: 1 MATG--TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF 58 MA G + K ++VTGG RGIG RA +GA V + + + + +++ Sbjct: 4 MAPGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFG 63 Query: 59 I-----LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLEL 113 + CDV+ D V + + G + ++ NAG + E + + F + ++ Sbjct: 64 VKTKAYQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSV-VKPATELTHEDFAFVYDV 122 Query: 114 NLLGTYTLTKLALPYL--RKSQGNVINISSLVGAI-------GQAQAVPYVATKGAVTAM 164 N+ G + + ++ +G+++ SS+ I G V Y ++K A + + Sbjct: 123 NVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNL 182 Query: 165 TKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEV 224 K LA + + G+RVN +SPG + T + + D +A+ PL R QP E+ Sbjct: 183 VKGLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQAS------NIPLNRFAQPEEM 236 Query: 225 GAAAVFLASE-ANFCTGIELLVTGGAEL 251 A+ L S+ A + TG E + GG + Sbjct: 237 TGQAILLLSDHATYMTGGEYFIDGGQLI 264 >3GDF-A nrPDB Length = 267 Score = 177 bits (450), Expect = 4e-45, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 20/256 (7%) Query: 7 YAGKVVVVTGGG--RGIGAGIVRAFVNSGARVVICDKD-----ESGGRALEQELP-GAVF 58 GKVVVVTG +G+G R GA V I E + LE+ A Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKA 77 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 C V + + LV + + FG++D + NAG + S + + +++++L GT Sbjct: 78 YKCQVDSYESCEKLVKDVVADFGQIDAFIANAG-ATADSGILDGSVEAWNHVVQVDLNGT 136 Query: 119 YTLTKLALPYLRKSQ-GNVINISSLVGAIGQ--AQAVPYVATKGAVTAMTKALALDESPY 175 + K + ++ G+++ +S+ G I + Y K M ++LA + + Sbjct: 137 FHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEWRDF 196 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEA 235 RVN ISPG I T L+ +P + M P+GR G E+ A V+ AS+A Sbjct: 197 A-RVNSISPGYIDT----GLSDFVPKETQQLWHSM--IPMGRDGLAKELKGAYVYFASDA 249 Query: 236 N-FCTGIELLVTGGAE 250 + + TG +LL+ GG Sbjct: 250 STYTTGADLLIDGGYT 265 >5O3Z-A nrPDB Length = 263 Score = 175 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 16/257 (6%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL------PGAVFILCDV 63 +V VV GGG+ +GA + +G V + D +ES L + A D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 T E V+ L FGR D +V +AG + F L++NL+G + ++ Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVA-KAAPITQFRLTDFDLSLQVNLVGYFLCSR 125 Query: 124 LALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181 + + G +I I+S G +G Y A K +T++LALD + YG+ V+ Sbjct: 126 EFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHS 185 Query: 182 ISPGN-IWTPLWEELAALMPD-----PRATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 + GN + +P+++ L + P + PL R +V +F AS+ Sbjct: 186 LMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDK 245 Query: 235 ANFCTGIELLVTGGAEL 251 A +CTG + VTGG + Sbjct: 246 AAYCTGQSINVTGGQVM 262 >5KOI-A nrPDB Length = 293 Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats. Identities = 57/255 (22%), Positives = 104/255 (40%), Gaps = 15/255 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRA---LEQELPGAVFILC 61 GK ++ G + GI + GA + + ++ G+ L +++ + C Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVLPC 85 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQR----PEETSAQGFRQLLELNLLG 117 DV V + E +++G LD +V+ G + + T+ + F + + ++ Sbjct: 86 DVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYS 145 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + + A + K G+++ ++ K A+ AM + LA D P G+ Sbjct: 146 FTEVAQRAEKLM-KDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGI 204 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 RVN IS G + T A + D RA PL R +VG +AV+L S+ ++ Sbjct: 205 RVNAISAGPVRT----LAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSS 260 Query: 237 FCTGIELLVTGGAEL 251 TG V G + Sbjct: 261 GVTGEIHFVDSGYNI 275 >1E3W-A nrPDB Length = 261 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 77/261 (29%), Positives = 120/261 (45%), Gaps = 20/261 (7%) Query: 1 MATGTR-YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVF 58 MA R G V V+TGG G+G + V GA V+ D S G ++L G +F Sbjct: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET-----SAQGFRQLLEL 113 +VT E +V+ ++ +FGR+D VN AG + E + + F++++ + Sbjct: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 Query: 114 NLLGTYTLTKLALPYLRK-------SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 NL+GT+ + +L + + +G +IN +S+ GQ Y A+KG + MT Sbjct: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 Query: 167 ALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGA 226 +A D +P G+RV I+PG TPL L PD + P R+G PAE Sbjct: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTL----PDTVRNFLASQVPFP-SRLGDPAEYAH 235 Query: 227 AAVFLASEANFCTGIELLVTG 247 + E F G + + G Sbjct: 236 LV-QMVIENPFLNGEVIRLDG 255 >3OIG-A nrPDB Length = 266 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 61/256 (23%), Positives = 108/256 (42%), Gaps = 16/256 (6%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQ-----ELPGAVFI 59 G+ +VV G R I GI R+ +GAR++ E +++ + + ++ + Sbjct: 5 LEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIIL 64 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE---TSAQGFRQLLELNLL 116 CDVT + +++T + + G + + + + E T+ GF ++ Sbjct: 65 PCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSY 124 Query: 117 GTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + K A P + + G+++ ++ L G + K ++ A K LA D Sbjct: 125 SLTAVVKAARPMMTE-GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKEN 183 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-A 235 +RVN IS G I T A + D + +++ PL R P EVG A FL S+ + Sbjct: 184 IRVNSISAGPIRT----LSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMS 239 Query: 236 NFCTGIELLVTGGAEL 251 TG L V G + Sbjct: 240 RGITGENLHVDSGFHI 255 >4TRR-A nrPDB Length = 269 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 113/260 (43%), Gaps = 14/260 (5%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFIL 60 + GK VVTG GIG I +GA V I D ++ G A+ E+ A+ + Sbjct: 10 SNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVA 69 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DVT E+ V T + + FG +D +V+NAG E S ++++ +++ G + Sbjct: 70 MDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQI-VNPIENYSFADWKKMQAIHVDGAFL 128 Query: 121 LTKLALPYLRK--SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 TK AL ++ K G VI + S+ YV K + + + LA + + + VR Sbjct: 129 TTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVR 188 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPL------GRMGQPAEVGAAAVFL- 231 + + PG + TPL ++ E ++ + + G +V +FL Sbjct: 189 SHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLS 248 Query: 232 ASEANFCTGIELLVTGGAEL 251 A + TG +V+ G + Sbjct: 249 AFPSAALTGQSFIVSHGWFM 268 >4ZJU-A nrPDB Length = 275 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 60/254 (23%), Positives = 98/254 (38%), Gaps = 14/254 (5%) Query: 7 YAGKVVVVTGGGR--GIGAGIVRAFVNSGARVVICDKDES---GGRALEQELPGAVFILC 61 AGK ++ G I GI +A GA + +E ++ + C Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVFPC 73 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNLLG 117 DV + ++ +E + + +D VV++ G P + T GF+ +++ Sbjct: 74 DVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISAYS 133 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + + A P L+ QG ++ ++ K ++ A + LA G+ Sbjct: 134 FVAMARAAKPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVDGI 193 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 RVN IS G I T A+ + R + PL R EVG AA+FL S A+ Sbjct: 194 RVNAISAGPIRT----LAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLCSPWAS 249 Query: 237 FCTGIELLVTGGAE 250 TG L V G Sbjct: 250 GITGEILYVDAGFN 263 >5YCX-A nrPDB Length = 266 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 106/256 (41%), Gaps = 16/256 (6%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICD---KDESGGRALEQELPG--AVFI 59 GK VV G R I GI R+ N+GA+++ + E R L L G ++ + Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVL 65 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNN---AGHHPPPQRPEETSAQGFRQLLELNLL 116 CDVT ++++ + G + V + A +TS GF ++ Sbjct: 66 PCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISAF 125 Query: 117 GTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + + A + + GN++ ++ L G K ++ A K LA D +G Sbjct: 126 SLTAVAREAKKVMTE-GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQHG 184 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-A 235 +RVN IS G I T A + D + +RE PL R EVG AVFL S+ A Sbjct: 185 IRVNAISAGPIRT----LSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLA 240 Query: 236 NFCTGIELLVTGGAEL 251 TG + V G + Sbjct: 241 RGVTGENIHVDSGYHI 256 >4RGB-A nrPDB Length = 294 Score = 173 bits (439), Expect = 8e-44, Method: Composition-based stats. Identities = 69/271 (25%), Positives = 119/271 (43%), Gaps = 27/271 (9%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK----------------DESGGRALE 50 G+VV +TG RG G GA +V D E R +E Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 51 QELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQL 110 + +F DV + ++ + + +FG +D V+ NAG + S + R Sbjct: 83 KTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDAS-EALRLG 141 Query: 111 LELNLLGTYTLTKLALPYLRKSQ--GNVINISSLVGAI----GQAQAVPYVATKGAVTAM 164 L++ L+G + ++A+P++++ GN+I SS++ + G+ Y+ +K A+T + Sbjct: 142 LDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGL 201 Query: 165 TKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRAT---IREGMLAQPLGRMGQP 221 ++ AL + +RVN ++P N TP+ E AL + A P M +P Sbjct: 202 VRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEP 261 Query: 222 AEVGAAAVFLASEA-NFCTGIELLVTGGAEL 251 +V A +FL S+A TG L V G ++ Sbjct: 262 RDVSNAILFLISDAGRSFTGSVLKVDAGMDV 292 >2O23-A nrPDB Length = 265 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 82/269 (30%), Positives = 123/269 (45%), Gaps = 20/269 (7%) Query: 1 MATGTR-YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVF 58 MA R G V V+TGG G+G V GA V+ D SGG A ++L VF Sbjct: 3 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 62 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRP-----EETSAQGFRQLLEL 113 DVT E DV+T ++ +FGR+D VN AG + + + + F+++L++ Sbjct: 63 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 122 Query: 114 NLLGTYTLTKLALPYLRK-------SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 NL+GT+ + +L + + +G +IN +S+ GQ Y A+KG + MT Sbjct: 123 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 182 Query: 167 ALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGA 226 +A D +P G+RV I+PG TPL L P+ + P R+G PAE Sbjct: 183 PIARDLAPIGIRVMTIAPGLFGTPLLTSL----PEKVCNFLASQVPFP-SRLGDPAEYAH 237 Query: 227 AAVFLASEANFCTGIELLVTGGAELGYGC 255 E F G + + G + G Sbjct: 238 LV-QAIIENPFLNGEVIRLDGAIRMQPGS 265 >2BGM-A nrPDB Length = 278 Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats. Identities = 63/232 (27%), Positives = 115/232 (49%), Gaps = 8/232 (3%) Query: 26 VRAFVNSGARVVICDKDESGGRALEQELPG---AVFILCDVTQEDDVKTLVSETIRRFGR 82 + FV GA+VVI D + G+ + + F+ CDVT+++DV+ LV TI + G+ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 83 LDCVVNNAGH-HPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLR-KSQGNVINIS 140 LD + N G P E + F++++++N+ G + + K A + +G+++ + Sbjct: 93 LDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTA 152 Query: 141 SLVGAIGQAQAVP-YVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALM 199 S+ Y ATK AV +T +L + YG+RVNC+SP + +PL ++ + Sbjct: 153 SISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVF-GV 211 Query: 200 PDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAE 250 R A G + + +V A +LA + + + +G+ L++ GG Sbjct: 212 DSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYT 263 >5CFZ-A nrPDB Length = 305 Score = 171 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 57/255 (22%), Positives = 104/255 (40%), Gaps = 15/255 (5%) Query: 7 YAGKVVVVTGGGR--GIGAGIVRAFVNSGARVVICDKDES---GGRALEQELPGAVFILC 61 +GK ++VTG I GI +A GA + +++ +L + + C Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 106 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNLLG 117 DV ++ + T+ +E + + + D V++ G P Q + + +GF+ +++ Sbjct: 107 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 166 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + K L ++ +S L K ++ A + +A P GV Sbjct: 167 FVAMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 225 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 RVN IS G I T A+ + D R + P+ R +VG +A FL S+ + Sbjct: 226 RVNAISAGPIRT----LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 281 Query: 237 FCTGIELLVTGGAEL 251 +G + V GG + Sbjct: 282 GISGEVVHVDGGFSI 296 >4CR6-A nrPDB Length = 271 Score = 171 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 118/253 (46%), Gaps = 13/253 (5%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R AGK +VTG GIG V A++ GA VV D A E PGA+ I CD+ Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLA-PRLAATRYEEPGAIPIACDLAD 70 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + +++ + R G LD +V + S + + +++N+ GT+ + Sbjct: 71 RAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAG 130 Query: 126 LPYLRKSQ-------GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + +I I S+ + + +A YVA KG V +T+A+A+D + +G+ Sbjct: 131 ARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGIL 190 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VN I+PG + +PR + + LGR G P EV AAVFLA + ++F Sbjct: 191 VNMIAPGPVD---VTGNNTGYSEPR-LAEQVLDEVALGRPGLPEEVATAAVFLAEDGSSF 246 Query: 238 CTGIELLVTGGAE 250 TG + + GG Sbjct: 247 ITGSTITIDGGLS 259 >4EGF-A nrPDB Length = 266 Score = 171 bits (433), Expect = 4e-43, Method: Composition-based stats. Identities = 76/259 (29%), Positives = 113/259 (43%), Gaps = 13/259 (5%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP-----GA 56 A R GK ++TG +GIGA I RAF +GAR+V+ +D S A + L Sbjct: 13 AGVLRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDV 72 Query: 57 VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL 116 + D+ + D L FG LD +VNNAG PQ +T Q F + +NL Sbjct: 73 HTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISH-PQPVVDTDPQLFDATIAVNLR 131 Query: 117 GTYTLTKLALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 L + G +I ++S Y +K + TK LA + P Sbjct: 132 APALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGP 191 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 +G+R N + P + T + + + A + PLGR P EV A V+LAS+ Sbjct: 192 HGIRANSVCPTVVLTEMGQRVWG----DEAKSAPMIARIPLGRFAVPHEVSDAVVWLASD 247 Query: 235 -ANFCTGIELLVTGGAELG 252 A+ G+++ V GG +G Sbjct: 248 AASMINGVDIPVDGGYTMG 266 >3PXX-A nrPDB Length = 287 Score = 170 bits (432), Expect = 4e-43, Method: Composition-based stats. Identities = 77/285 (27%), Positives = 112/285 (39%), Gaps = 41/285 (14%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK----------------DESGGRAL 49 R KVV+VTGG RG G GA +++ D E G + Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 50 EQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 E+ A DV V ++ + FG+LD VV NAG P Q F Sbjct: 67 EKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGA---HLPVQAFAD 123 Query: 110 LLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP-----------YVATK 158 +++ +G ALPYL S ++I S+ G I AQ Y K Sbjct: 124 AFDVDFVGVINTVHAALPYLT-SGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAK 182 Query: 159 GAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELA---ALMPDPRATIR-EGMLAQP 214 V + T LA +P +R N I P N+ T + PD A R + +LA P Sbjct: 183 QLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFP 242 Query: 215 LGR-----MGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGY 253 + + +++ A FLAS+ + + TG++ V GA L + Sbjct: 243 AMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAMLKF 287 >4NR0-A nrPDB Length = 273 Score = 170 bits (432), Expect = 4e-43, Method: Composition-based stats. Identities = 59/256 (23%), Positives = 101/256 (39%), Gaps = 16/256 (6%) Query: 7 YAGKVVVVTGGGR--GIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-----AVFI 59 GK ++ G I +GI A GA + +++ +E+ G + Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNL 115 CDV + ++ + + + + LD +V++ G P Q + T+ +GFR +++ Sbjct: 64 PCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISA 123 Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 L K ++ G+++ +S L K ++ A + LA Sbjct: 124 YSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGAE 183 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE- 234 G RVN +S G I T A+ + R + PL R EVG A FL S+ Sbjct: 184 GTRVNAVSAGPIRT----LAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDL 239 Query: 235 ANFCTGIELLVTGGAE 250 A+ +G L V GG Sbjct: 240 ASGISGEILYVDGGFN 255 >4JQC-A nrPDB Length = 282 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 57/255 (22%), Positives = 104/255 (40%), Gaps = 15/255 (5%) Query: 7 YAGKVVVVTGGGR--GIGAGIVRAFVNSGARVVICDKDES---GGRALEQELPGAVFILC 61 +GK ++VTG I GI +A GA + +++ +L + + C Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 83 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNLLG 117 DV ++ + T+ +E + + + D V++ G P Q + + +GF+ +++ Sbjct: 84 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 143 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 + K L ++ +S L K ++ A + +A P GV Sbjct: 144 FVAMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 202 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 RVN IS G I T A+ + D R + P+ R +VG +A FL S+ + Sbjct: 203 RVNAISAGPIRT----LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 258 Query: 237 FCTGIELLVTGGAEL 251 +G + V GG + Sbjct: 259 GISGEVVHVDGGFSI 273 >2GDZ-A nrPDB Length = 267 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 69/257 (26%), Positives = 116/257 (45%), Gaps = 24/257 (9%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD-ESGGRALEQ-----ELPGAV 57 GKV +VTG +GIG A + GA+V + D + E+G + E + Sbjct: 2 AHMVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTL 61 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 FI CDV + ++ + + FGRLD +VNNAG + + + + + L++NL+ Sbjct: 62 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVS 112 Query: 118 TYTLTKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKA--LALD 171 + T L L Y+ K G +IN+SSL G + AQ Y A+K + T++ LA + Sbjct: 113 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 172 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMG--QPAEVGAAAV 229 GVR+N I PG + T + E + + + + + G P + + Sbjct: 173 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 232 Query: 230 FLASEANFCTGIELLVT 246 L + + G + +T Sbjct: 233 TLIED-DALNGAIMKIT 248 >5IZ4-A nrPDB Length = 271 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 76/262 (29%), Positives = 123/262 (46%), Gaps = 16/262 (6%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL-------EQELPGAV 57 T+ + V V+TG GIGA F +G V I + D+S A + Sbjct: 10 TQSSTPVCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTL 69 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHP--PPQRPEETSAQGFRQLLELNL 115 DV ++ D + V R+ R+D ++N AG P ++ F ++ +NL Sbjct: 70 IFDADVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNL 129 Query: 116 LGTYTLTKLALPYLRKSQG-----NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALAL 170 +G Y +T+ A+P LR+S +V+N+SSL G G ++ Y A+KGAV +T +LA Sbjct: 130 IGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLAR 189 Query: 171 DESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVF 230 + +P+ +RVN ++PG + L + + + PL R+ +PAE+ A F Sbjct: 190 NLAPH-IRVNALAPGMVDDGLLLRVLDAAA-YDGVLSRMTESAPLKRVSRPAEIAELAWF 247 Query: 231 LASEANFCTGIELLVTGGAELG 252 L + A TG + G LG Sbjct: 248 LTAHAPAITGQVIAAENGLLLG 269 >4ALL-A nrPDB Length = 277 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 63/255 (24%), Positives = 100/255 (39%), Gaps = 16/255 (6%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-----PGAVFI 59 K V+ G R I G+ + GA++V + E + LE+ L P A Sbjct: 25 LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLY 84 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNN---AGHHPPPQRPEETSAQGFRQLLELNLL 116 DV +++V + + G +D V ++ A R ETS +GF +++ Sbjct: 85 QIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSY 144 Query: 117 GTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + A + G+++ + L G K ++ A K LALD P Sbjct: 145 SLTIVAHEAKKLM-PEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDN 203 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-A 235 +RVN IS G I T A + ++E PL R EVG A +L S+ + Sbjct: 204 IRVNAISAGPIRT----LSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLS 259 Query: 236 NFCTGIELLVTGGAE 250 + TG + V G Sbjct: 260 SGVTGENIHVDSGFH 274 >4J3F-A nrPDB Length = 280 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 99/254 (38%), Gaps = 13/254 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDE--SGGRALEQELPGAVFILCD 62 AGK +++TG + I GI +A GA + + L E A + CD Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEFNPAAVLPCD 83 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQ----RPEETSAQGFRQLLELNLLGT 118 V + ++K L E + + LD +V++ P Q + + +GF +++ Sbjct: 84 VISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDISAYSF 143 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 L K ++ +++ ++ + K ++ A + AL G++ Sbjct: 144 AALAKEGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGEDGIK 203 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 VN +S G I T A+ + + + + + PL + EVG FL S+ A Sbjct: 204 VNAVSAGPIKT----LAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAFLCSDMATG 259 Query: 238 CTGIELLVTGGAEL 251 TG + V G Sbjct: 260 ITGEVVHVDAGYHC 273 >5I9N-A nrPDB Length = 276 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 64/269 (23%), Positives = 100/269 (37%), Gaps = 15/269 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVIC---DKDESGGRALEQELPGAVFILC 61 GK +++TG R I GI +A GA + D+ + E + C Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPC 63 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHP----PPQRPEETSAQGFRQLLELNLLG 117 DV + + L + + LD +V++ G P + + + FR +++ Sbjct: 64 DVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYS 123 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV 177 L K ALP L +++ +S L K A+ A + LA+ GV Sbjct: 124 FPALAKAALPMLSDD-ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGV 182 Query: 178 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-AN 236 RVN IS G I T A+ + + PL R +VG A FL S+ A+ Sbjct: 183 RVNAISAGPIKT----LAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLAS 238 Query: 237 FCTGIELLVTGGAELGYGCKASRSTPVDA 265 T + V G G A + A Sbjct: 239 GVTAEVMHVDSGFNAVVGGMAGLEEKLAA 267 >1W73-A nrPDB Length = 302 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 78/260 (30%), Positives = 121/260 (46%), Gaps = 14/260 (5%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-----PG 55 M + GKV +TGGG G+G G+ + GA+ VI + +A +++ Sbjct: 18 MLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK 77 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 I CDV D V+ VSE I+ G + V+NNA + E S ++ + ++ L Sbjct: 78 VHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNF-ISPTERLSPNAWKTITDIVL 136 Query: 116 LGTYTLTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDES 173 GT +T L K+ ++I+++ G VP + K V AM+K+LA + Sbjct: 137 NGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWG 196 Query: 174 PYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGML-AQPLGRMGQPAEVGAAAVFLA 232 YG+R N I PG I T + A DP T + M+ P GR+G E+ A FL Sbjct: 197 KYGMRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLC 252 Query: 233 SE-ANFCTGIELLVTGGAEL 251 S+ A++ G + GG E+ Sbjct: 253 SDYASWINGAVIKFDGGEEV 272 >2X9N-A nrPDB Length = 288 Score = 161 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 36/278 (12%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR-ALEQELPG-----AV 57 G+ VVTG + IG I +G RVVI + + +L EL AV Sbjct: 18 GSHMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAV 77 Query: 58 FILCDVTQ----EDDVKTLVSETIRRFGRLDCVVNNA-GHHPPPQRPEETSAQ------- 105 D+T + +++ R FGR D +VNNA +P P + Sbjct: 78 VCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVE 137 Query: 106 -GFRQLLELNLLGTYTLT-------KLALPYLRKSQGNVINISSLVGAIGQAQAVPYVAT 157 +L+ N + + LT K P S +++N+ + Y Sbjct: 138 TQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMG 197 Query: 158 KGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGR 217 K A+ +T++ AL+ +PYG+RVN ++PG P+ A+ + + R + PLGR Sbjct: 198 KHALVGLTQSAALELAPYGIRVNGVAPGVSLLPV-----AMGEEEKDKWRRKV---PLGR 249 Query: 218 M-GQPAEVGAAAVFLAS-EANFCTGIELLVTGGAELGY 253 ++ A +FL S A + TG + V GG L + Sbjct: 250 REASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVH 287 >4DA9-A nrPDB Length = 280 Score = 160 bits (406), Expect = 4e-40, Method: Composition-based stats. Identities = 69/259 (26%), Positives = 113/259 (43%), Gaps = 16/259 (6%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG-----RALEQELPGAVFI 59 T+ A V +VTGG RGIG GI RA SG + I ++ G L +F+ Sbjct: 25 TQKARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFL 84 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPP-QRPEETSAQGFRQLLELNLLGT 118 D+ + V + FGR+DC+VNNAG + + F ++ +NL GT Sbjct: 85 RADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGT 144 Query: 119 YTLTKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 T+ L + S +INI+S+ + + + Y +K + A ++ LAL + Sbjct: 145 VFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAE 204 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLA-S 233 G+ V + PG I + + ++ + P+ R G+P ++G LA Sbjct: 205 TGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGL-----VPMRRWGEPEDIGNIVAGLAGG 259 Query: 234 EANFCTGIELLVTGGAELG 252 + F TG + GG +G Sbjct: 260 QFGFATGSVIQADGGLSIG 278 >3OML-A nrPDB Length = 613 Score = 160 bits (405), Expect = 5e-40, Method: Composition-based stats. Identities = 64/265 (24%), Positives = 103/265 (38%), Gaps = 28/265 (10%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK---------DESGGRALEQELPGA 56 RY G+V VVTG G G+G F GA+VV+ D + + E+ A Sbjct: 16 RYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 57 VF-ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 + D D ++ I+ FGR+D +VNNAG + TS Q + + +++L Sbjct: 76 GGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVK-TSEQDWNLVNDVHL 134 Query: 116 LGTYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 G++ T+ A PY++K G +I SS G G V Y A K + + +A++ + Sbjct: 135 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234 V N I P T ++PD + P + +L E Sbjct: 195 NNVLCNVIVP----TAASRMTEGILPDILFNELK------------PKLIAPVVAYLCHE 238 Query: 235 ANFCTGIELLVTGGAELGYGCKASR 259 + G + G + Sbjct: 239 SCEDNGSYIESAAGWATKLHMVRGK 263 >3RKU-A nrPDB Length = 287 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 50/238 (21%), Positives = 95/238 (39%), Gaps = 16/238 (6%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNS---GARVVICDKDESGGRALEQEL------ 53 R A K V++TG GIG ++ + ++++ + L++ + Sbjct: 27 AAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPN 86 Query: 54 PGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLEL 113 D+TQ + +K + + F +D +VNNAG R + + + + + + Sbjct: 87 AKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDT 146 Query: 114 NLLGTYTLTKLALPYLR-KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDE 172 N+ +T+ LP + K+ G+++N+ S+ G Y A+K AV A T +L + Sbjct: 147 NVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKEL 206 Query: 173 SPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVF 230 +RV I+PG + T L + PL +V V+ Sbjct: 207 INTKIRVILIAPGLVETEF--SLVRYRGNEEQAKNVYKDTTPL----MADDVADLIVY 258 >3PPI-A nrPDB Length = 281 Score = 156 bits (395), Expect = 8e-39, Method: Composition-based stats. Identities = 78/261 (29%), Positives = 112/261 (42%), Gaps = 22/261 (8%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFI 59 M T ++ G +V+GG G+G VR G VVI D G+AL EL A F+ Sbjct: 22 MVTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFV 81 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQ-----GFRQLLELN 114 +VT ED V + + GRL V G QR + GF + ++L Sbjct: 82 STNVTSEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLY 140 Query: 115 LLGTYTLTK-------LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKA 167 L GTY + + A P +G ++ +S+ G GQ Y A K V +T A Sbjct: 141 LNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIA 200 Query: 168 LALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPL-GRMGQPAEVGA 226 A D S G+RVN I+PG + TP+ E + + + P R+G P E Sbjct: 201 AARDLSSAGIRVNTIAPGTMKTPIMESVG------EEALAKFAANIPFPKRLGTPDEFAD 254 Query: 227 AAVFLASEANFCTGIELLVTG 247 AA FL + + G + + G Sbjct: 255 AAAFLLT-NGYINGEVMRLDG 274 >2PD3-A nrPDB Length = 275 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 63/254 (24%), Positives = 107/254 (42%), Gaps = 14/254 (5%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDES---GGRALEQELPGAVFILC 61 GK ++ G + I GI ++ N GA + +ES R + QEL Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVYEL 63 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQR---PEETSAQGFRQLLELNLLGT 118 DV++E+ K+L + + G LD +V++ P ETS F +E+++ Sbjct: 64 DVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSL 123 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 LT P L + +V+ +S L A K A+ + + LA+D + +R Sbjct: 124 IELTNTLKPLL-NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIR 182 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANF- 237 VN +S G I T ++ + D R ++ + PL + EVG A ++L S + Sbjct: 183 VNALSAGPIRT----LASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSG 238 Query: 238 CTGIELLVTGGAEL 251 +G V G + Sbjct: 239 VSGEVHFVDAGYHV 252 >2NWQ-A nrPDB Length = 272 Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats. Identities = 51/232 (21%), Positives = 86/232 (37%), Gaps = 12/232 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG---AVFIL 60 G+ + + +TG G G R F +G +V+ + E +AL EL + + Sbjct: 17 GSHMSS-TLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLT 75 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DV + V F L ++NNAG + + +++ N+ G Sbjct: 76 LDVRDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLY 135 Query: 121 LTKLALPYLRKS--QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 T+L LP L +++N+ S+ G + Y TK V + L D GVR Sbjct: 136 STRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVR 195 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVF 230 V + PG + L D + A P+ QP ++ + Sbjct: 196 VTNLEPGLCESEF--SLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFW 241 >1P33-A nrPDB Length = 289 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 62/286 (21%), Positives = 106/286 (37%), Gaps = 53/286 (18%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELP-----GAVFILCDVT 64 V +VTG + +G+ I A G V + + + L L A+ + D++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 65 QEDD-----------------VKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEET---- 102 LV +GR D +VNNA +P P ++ Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 103 SAQGFRQLLEL--------NLLGTYTLTKLALPYLRKSQG-------NVINISSLVGAIG 147 S+ G ++ LE+ N + Y L K + ++ +++N+ + + Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 148 QAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIR 207 Y K A+ +T++ AL+ + +RVN +SPG P P + Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--------DDMPFSVQE 240 Query: 208 EGMLAQPL-GRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 251 + PL R EV +FL S +A + TG + V GG L Sbjct: 241 DYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >4DRY-A nrPDB Length = 281 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 58/217 (26%), Positives = 93/217 (42%), Gaps = 15/217 (6%) Query: 25 IVRAFVNSGARVVICDKDESGGRALEQELPG-----AVFILCDVTQEDDVKTLVSETIRR 79 I +A G VVI + A E+ G ++CDV D V L + Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAE 108 Query: 80 FGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK---SQGNV 136 F RLD +VNNAG + PP EE + + + ++ NL G + T+ A ++ G + Sbjct: 109 FARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTPRGGRI 168 Query: 137 INISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELA 196 IN S+ + + PY ATK A+T +TK+ ALD + + I GN T + ++ Sbjct: 169 INNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATDMTARMS 228 Query: 197 ALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 + + P+ + A V++AS Sbjct: 229 TGVLQANGEV-AAEPTIPI------EHIAEAVVYMAS 258 >4NK4-A nrPDB Length = 301 Score = 146 bits (369), Expect = 9e-36, Method: Composition-based stats. Identities = 58/263 (22%), Positives = 96/263 (36%), Gaps = 18/263 (6%) Query: 7 YAGKVVVVTGGGR--GIGAGIVRAFVNSGARVVICDKDESGGRAL---EQELPGAVFILC 61 GK ++ G I GI + ++GA++ + ES G+ L + I C Sbjct: 39 LKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVDSDFMIPC 98 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE---ETSAQGFRQLLELNLLGT 118 +V + L R+ LD VV++ + TS F Q + ++ Sbjct: 99 NVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVSCFSF 158 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + A + G +I ++ K A+ + TK LA D +R Sbjct: 159 TEIVRRAAQLM-PHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNIR 217 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 +N IS G + T A + + R PL R ++G +A++L S +N Sbjct: 218 INAISAGPVRT----LAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNG 273 Query: 238 CTGIELLVTGGAELGYGCKASRS 260 TG V GY A S Sbjct: 274 VTGEIHYVD----CGYNIVAMPS 292 >5PGZ-A nrPDB Length = 276 Score = 145 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 53/211 (25%), Positives = 91/211 (43%), Gaps = 10/211 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG-----RALEQELPGAVFILC 61 GK V+VTG +GIG + GA VV+ + E G R LE A +I Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 + + + + + G LD ++ N + R+++E+N L + Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHD-DIHSVRRVMEVNFLSYVVM 134 Query: 122 TKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN- 180 + ALP L++S G++ ISSL G + Q PY A+K A+ + + V V+ Sbjct: 135 STAALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSI 194 Query: 181 --CISPGNIWTPLWEELAALMPDPRATIREG 209 C+ G I T + + + + +A+ +E Sbjct: 195 TLCVL-GLIDTETAMKEISGIINAQASPKEE 224 >2QHX-A nrPDB Length = 328 Score = 145 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 70/287 (24%), Positives = 109/287 (37%), Gaps = 55/287 (19%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELP-----GAVFILCDVT 64 V +VTG + +G I G V + + + AL L A+ + D++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 65 QEDD-----------------VKTLVSETIRRFGRLDCVVNNAGHH--PPPQRPEETSAQ 105 LV+ +GR D +VNNA P R +E + Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 106 ---GFRQLLEL--------NLLGTYTLTKLALPYLR----KSQG---NVINISSLVGAIG 147 G R+ +E N + Y L K + K +G ++IN+ + Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 148 QAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIR 207 Y KGA+ +T++ AL+ +P +RVN + PG L+ L+ D + Sbjct: 228 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG---------LSVLVDDMPPAVW 278 Query: 208 EG-MLAQPL-GRMGQPAEVGAAAVFLA-SEANFCTGIELLVTGGAEL 251 EG PL R AEV +FL S+A + TG + V GG L Sbjct: 279 EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2BFA-A nrPDB Length = 288 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 70/287 (24%), Positives = 109/287 (37%), Gaps = 55/287 (19%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELP-----GAVFILCDVT 64 V +VTG + +G I G V + + + AL L A+ + D++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 65 QEDD-----------------VKTLVSETIRRFGRLDCVVNNAGHH--PPPQRPEETSAQ 105 LV+ +GR D +VNNA P R +E + Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 106 ---GFRQLLEL--------NLLGTYTLTKLALPYLR----KSQG---NVINISSLVGAIG 147 G R+ +E N + Y L K + K +G ++IN+ + Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 148 QAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIR 207 Y KGA+ +T++ AL+ +P +RVN + PG L+ L+ D + Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG---------LSVLVDDMPPAVW 238 Query: 208 EG-MLAQPL-GRMGQPAEVGAAAVFLA-SEANFCTGIELLVTGGAEL 251 EG PL R AEV +FL S+A + TG + V GG L Sbjct: 239 EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >5ILO-A nrPDB Length = 271 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 59/213 (27%), Positives = 91/213 (42%), Gaps = 20/213 (9%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSG-ARVVICDKDESGGR----ALEQELPGAVF 58 GT + GK VVTGG GIG + + + +G A+V I D ++ + Sbjct: 10 GTSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMI 69 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 I DV + V+ E + FG +D VVN AG + + ++ L +NL G Sbjct: 70 IKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIF---------NDKDVQRTLLVNLGGI 120 Query: 119 YTLTKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD--E 172 T ALPY+ K G V+N+SS+VG Y ATK + T+ LA + Sbjct: 121 INSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYY 180 Query: 173 SPYGVRVNCISPGNIWTPLWEELAALMPDPRAT 205 G++ + PG T ++ + P + Sbjct: 181 QRSGIKFVTVCPGATMTDMFTNFTEKIIFPETS 213 >3DWF-A nrPDB Length = 276 Score = 141 bits (356), Expect = 3e-34, Method: Composition-based stats. Identities = 52/201 (25%), Positives = 81/201 (40%), Gaps = 10/201 (4%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-----GRALEQELPGAVFILC 61 GK V+VTG +GIG I GA VV+ + + R LE A +I Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 + + V+E G LD ++ N + R+ +E+N L Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFH-GEIDNVRKSMEVNFHSFVVL 127 Query: 122 TKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN- 180 + A+P L +SQG++ +SS+ G I PY A+K A+ L + V V+ Sbjct: 128 SVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSI 187 Query: 181 --CISPGNIWTPLWEELAALM 199 CI G I T + + + Sbjct: 188 TLCIL-GLIDTETAIKATSGI 207 >3KZV-A nrPDB Length = 254 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 52/195 (26%), Positives = 98/195 (50%), Gaps = 5/195 (2%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI--CDKDESGGRALEQELPGAVF-ILCDVTQ 65 GKV++VTG RGIG IV + V+ + E+ + L+++ F ++ D+T+ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + +K LV+ ++ G++D +V NAG P Q E +++L ++N +L +A Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIA 121 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 185 LP L+K+ GNV+ +SS + + Y ++K A+ LA + V+ ++PG Sbjct: 122 LPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAPG 179 Query: 186 NIWTPLWEELAALMP 200 + T + + + Sbjct: 180 IVDTDMQVNIRENVG 194 >3UCF-A nrPDB Length = 223 Score = 137 bits (345), Expect = 5e-33, Method: Composition-based stats. Identities = 59/242 (24%), Positives = 100/242 (41%), Gaps = 26/242 (10%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 V VV GG GIGA + + + +V ++G D++ E V Sbjct: 8 VYVVLGGTSGIGAELAKQLESE-HTIVHVASRQTG---------------LDISDEKSVY 51 Query: 71 TLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLR 130 G D ++ AG + P + + + + G K YL+ Sbjct: 52 HYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGARYLK 107 Query: 131 KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTP 190 + G++ S ++ A A A+ A TK LA + +P +RVN ISPG T Sbjct: 108 Q-GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAISPGLTKTE 164 Query: 191 LWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAE 250 ++ + A D A + P+G++G+ +++ A +F A + ++ TG + V GGA Sbjct: 165 AYKGMNA--DDRDAMYQRTQSHLPVGKVGEASDIAMAYLF-AIQNSYMTGTVIDVDGGAL 221 Query: 251 LG 252 LG Sbjct: 222 LG 223 >1N5D-A nrPDB Length = 288 Score = 134 bits (338), Expect = 4e-32, Method: Composition-based stats. Identities = 58/255 (22%), Positives = 90/255 (35%), Gaps = 52/255 (20%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGA-RVVICDKDESGGRA----LEQELPGAVFILCDVT 64 +V +VTG +GIG IVR A VV+ +D + G+A L+ E F D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 ++ L + +G LD +VNNA P Q ++ N +GT + Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQA-ELTMKTNFMGTRNVCTE 123 Query: 125 ALPYLRKSQGNVINISSLVGAIGQAQAVP------------------------------- 153 LP L K QG V+N+SS G + P Sbjct: 124 LLP-LIKPQGRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTKNGV 182 Query: 154 ----------YVATKGAVTAMTKALALDE----SPYGVRVNCISPGNIWTPLWEELAALM 199 Y TK V+ +++ A + + +N PG + T + A Sbjct: 183 HRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDMGGPKAPKS 242 Query: 200 PDPRATIREGMLAQP 214 P+ A + P Sbjct: 243 PEVGAETPVYLALLP 257 >3E9N-A nrPDB Length = 245 Score = 133 bits (335), Expect = 7e-32, Method: Composition-based stats. Identities = 61/242 (25%), Positives = 95/242 (39%), Gaps = 16/242 (6%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVT 64 K+ VVTG G+G IV+ +V A E+ G I D+ Sbjct: 1 MSLKKKIAVVTGATGGMGIEIVKDLSRD--HIVYALGRNPEHLAALAEIEGVEPIESDIV 58 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 +E + V + + +D +V+ A E S + L+LN++ L++ Sbjct: 59 KEVLEEGGVDKL-KNLDHVDTLVHAAAVARD-TTIEAGSVAEWHAHLDLNVIVPAELSRQ 116 Query: 125 ALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184 LP LR + G VI I+S G Y A+K A+ + A +E+ G+RV+ +SP Sbjct: 117 LLPALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSP 176 Query: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELL 244 G TP+ L LM R + +P E+ A F +A T Sbjct: 177 GPTNTPM---LQGLMDSQGTNFRPEI-------YIEPKEIANAIRF-VIDAGETT-QITN 224 Query: 245 VT 246 V Sbjct: 225 VD 226 >2HRB-A nrPDB Length = 274 Score = 132 bits (333), Expect = 1e-31, Method: Composition-based stats. Identities = 54/256 (21%), Positives = 84/256 (32%), Gaps = 52/256 (20%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNS-GARVVICDKDESGGRA----LEQELPGAVFILCDV 63 +V +VTG RGIG I R VV+ +D + G+A L+ E F D+ Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDI 61 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 ++ L + +G L+ +VNNA P + L+ N T + Sbjct: 62 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKA-EMTLKTNFFATRNMCN 120 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQA-------------------------------- 151 LP + K G V+NISSL Sbjct: 121 ELLPIM-KPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNE 179 Query: 152 ---------VPYVATKGAVTAMTKALALDESPY----GVRVNCISPGNIWTPLWEELAAL 198 PY +K VT +++ LA + VN PG + T + + + Sbjct: 180 VHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIR 239 Query: 199 MPDPRATIREGMLAQP 214 + A + P Sbjct: 240 TVEEGAETPVYLALLP 255 >3BHI-A nrPDB Length = 276 Score = 128 bits (322), Expect = 2e-30, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 90/255 (35%), Gaps = 54/255 (21%) Query: 11 VVVVTGGGRGIGAGIVRAFVN--SGARVVICDKD----ESGGRALEQELPGAVFILCDVT 64 V +VTGG +GIG IVR SG VV+ +D ++ + L+ E F D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSG-DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 ++ L + +G LD +VNNAG P Q ++ N GT + Sbjct: 65 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 123 Query: 125 ALPYLRKSQGNVINISSLVGAIGQAQAVP------------------------------- 153 LP L K QG V+N+SS++ P Sbjct: 124 LLP-LIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGV 182 Query: 154 ----------YVATKGAVTAMTKALALDESPY----GVRVNCISPGNIWTPLWEELAALM 199 Y TK VT +++ A S + +N PG + T + A Sbjct: 183 HQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKS 242 Query: 200 PDPRATIREGMLAQP 214 P+ A + P Sbjct: 243 PEEGAETPVYLALLP 257 >1SNY-A nrPDB Length = 267 Score = 124 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 54/234 (23%), Positives = 97/234 (41%), Gaps = 27/234 (11%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGA---RVVICDKDESGGRALEQ---ELPGAVFILCDVTQ 65 +++TG RG+G G+V+A +N + ++ + LE + D+ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRN 83 Query: 66 EDDVKTLVSET--IRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 D LV++ + + L+ + NNAG P R +Q L+ N + L K Sbjct: 84 FDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAK 143 Query: 124 LALPYLRK------------SQGNVINISSLVGAI---GQAQAVPYVATKGAVTAMTKAL 168 LP L+K + +IN+SS++G+I Y +K A+ A TK+L Sbjct: 144 ACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSL 203 Query: 169 ALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPA 222 ++D P + + PG + T + A L G + Q + ++G+ Sbjct: 204 SVDLYPQRIMCVSLHPGWVKTDMGGSSAPL----DVPTSTGQIVQTISKLGEKQ 253 >1A27-A nrPDB Length = 289 Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats. Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 14/202 (6%) Query: 11 VVVVTGGGRGIGAGIVRAFVN---SGARVVICDKDE-------SGGRALEQELPGAVFIL 60 VV++TG GIG + + +V +D RAL + Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DV V GR+D +V NAG E +L++N++GT Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVVGTVR 120 Query: 121 LTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + + LP +++ G V+ S+ G +G Y A+K A+ + ++LA+ P+GV + Sbjct: 121 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 180 NCISPGNIWTPLWEELAALMPD 201 + I G + T E++ + Sbjct: 181 SLIECGPVHTAFMEKVLGSPEE 202 >6CGE-A nrPDB Length = 328 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 14/202 (6%) Query: 11 VVVVTGGGRGIGAGIVRAFVN---SGARVVICDKDE-------SGGRALEQELPGAVFIL 60 VV++TG GIG + + +V +D RAL + Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DV V GR+D +V NAG E +L++N++GT Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVVGTVR 121 Query: 121 LTKLALPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 + + LP +++ G V+ S+ G +G Y A+K A+ + ++LA+ P+GV + Sbjct: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 Query: 180 NCISPGNIWTPLWEELAALMPD 201 + I G + T E++ + Sbjct: 182 SLIECGPVHTAFMEKVLGSPEE 203 >4Q9N-A nrPDB Length = 298 Score = 120 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 68/291 (23%), Positives = 107/291 (36%), Gaps = 48/291 (16%) Query: 7 YAGKVVVVTGGG--RGIGAGIVRAFVNSGARV----------VICDKDESGGRALEQELP 54 GK+ + G G G G GI + +GA + + E G +EL Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 55 G------AVFILCDVTQED--------------------DVKTLVSETIRRFGRLDCVVN 88 A D + + V +V + + FG +D +V+ Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 89 NAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIG 147 + + P +P +TS +G+ L + +L P + + + I+++ L Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM-NAGASTISLTYLASMRA 184 Query: 148 QAQAVP-YVATKGAVTAMTKALALDESP-YGVRVNCISPGNIWTPLWEELAALMPDPRAT 205 A K A+ + TK LA + +GVRVN IS G PL + Sbjct: 185 VPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAG----PLASRAGKAIGFIERM 240 Query: 206 IREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAE-LGYG 254 + PL + +VGAAA FL S A+ TG L V GA +G G Sbjct: 241 VDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGANVMGIG 291 >3O26-A nrPDB Length = 311 Score = 119 bits (300), Expect = 9e-28, Method: Composition-based stats. Identities = 56/284 (19%), Positives = 96/284 (33%), Gaps = 81/284 (28%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-----PGAVFILCDVT 64 + VVTGG +GIG I + ++G VV+ +D + G ++L VF DVT Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 65 QE-DDVKTLVSETIRRFGRLDCVVNNAGHH-----------------------------P 94 + +L FG+LD +VNNAG P Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYEKP 132 Query: 95 PPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLR-KSQGNVINISSLVGAIGQAQA-- 151 Q + + + L++N G ++T++ +P L+ ++N+SS G++ Sbjct: 133 EAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVSNET 192 Query: 152 -----------------------------------------VPYVATKGAVTAMTKALAL 170 Y +K + A T+ LA Sbjct: 193 ALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRVLAN 252 Query: 171 DESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQP 214 + VNC+ PG + T + + + A + P Sbjct: 253 KIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALFP 294 >4HBG-A nrPDB Length = 286 Score = 119 bits (300), Expect = 9e-28, Method: Composition-based stats. Identities = 54/276 (19%), Positives = 97/276 (35%), Gaps = 62/276 (22%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELP---------------- 54 V +VTG RGIG I + G +I + + Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 55 --GAVFILCDVTQEDDVK------------TLVSETIRRFGR------LDCVVNNAGHHP 94 D D ++ + + + ++ ++ ++N AG Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL-T 124 Query: 95 PPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGN------------VINISSL 142 T+A + ++ +N + T+T + + Y+ KSQ ++NISS+ Sbjct: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 Query: 143 --VGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIW-TPLWEELAALM 199 G + Y A+K A++ T+ LA + P +R ISPG + T + + L Sbjct: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 Query: 200 PDPRATIREGMLAQPLGRMGQ--PAEVGAAAVFLAS 233 + ML + +G G PAE+ L S Sbjct: 245 KE--------MLERTIGASGTSAPAEIAEEVWSLYS 272 >1FJH-A nrPDB Length = 257 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 61/271 (22%), Positives = 109/271 (40%), Gaps = 55/271 (20%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 ++V++G GIGA + +G ++V D ++ ++ D++ + K Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE-------------VIADLSTAEGRK 49 Query: 71 TLVSETIRRF-GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 +++ + + +D +V AG P + ++ +N G L LP L Sbjct: 50 QAIADVLAKCSKGMDGLVLCAGLGPQTKVLGN--------VVSVNYFGATELMDAFLPAL 101 Query: 130 RK-SQGNVINISSLVG----------------------------AIGQAQAVPYVATKGA 160 +K Q + ISS+ A Q + Y +K A Sbjct: 102 KKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNA 161 Query: 161 VTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQ 220 +T + A GVR+N I+PG TPL L A + DPR P+GR + Sbjct: 162 LTVAVRKRAAAWGEAGVRLNTIAPGATETPL---LQAGLQDPRYGESIAKFVPPMGRRAE 218 Query: 221 PAEVGAAAVFLAS-EANFCTGIELLVTGGAE 250 P+E+ + FL S A++ G ++++ GG + Sbjct: 219 PSEMASVIAFLMSPAASYVHGAQIVIDGGID 249 >5L51-A nrPDB Length = 324 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 91/293 (31%), Gaps = 88/293 (30%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG---------AVFIL 60 + VVTG +GIG I + + G V++ +DE G + L V Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGH---------------------------- 92 DV V LV +FG LD +VNNAG Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSGAA 135 Query: 93 -----HPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG-NVINISSLVGAI 146 HP + + ++ +E N G+ +T+ +P L++S ++N+SS + ++ Sbjct: 136 KTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLSSL 195 Query: 147 -------------------------------------------GQAQAVPYVATKGAVTA 163 Y +K A+ A Sbjct: 196 VFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAALNA 255 Query: 164 MTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLG 216 T+ +A + R+N + PG T L A + P G Sbjct: 256 YTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQFTDAEAAEAPVKLALLPQG 306 >2DKN-A nrPDB Length = 255 Score = 115 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 53/269 (19%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 V+ +TG GIGA + +G V+ D+ ++ I D++ + Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQAD-------------IEADLSTPGGRE 49 Query: 71 TLVSETIRRFGR-LDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 T V+ + R G LD +V AG ++ +N G L L Sbjct: 50 TAVAAVLDRCGGVLDGLVCCAGVGVTAANSG--------LVVAVNYFGVSALLDGLAEAL 101 Query: 130 -RKSQGNVINISSLVGAIGQAQAVP--------------------------YVATKGAVT 162 R Q + + S+ A +P Y +K AVT Sbjct: 102 SRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVT 161 Query: 163 AMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPA 222 + + +D + GVR+N ++PG + TPL L A DPR PLGR +P Sbjct: 162 CLARRNVVDWAGRGVRLNVVAPGAVETPL---LQASKADPRYGESTRRFVAPLGRGSEPR 218 Query: 223 EVGAAAVFLAS-EANFCTGIELLVTGGAE 250 EV A FL +A+F G L V GG + Sbjct: 219 EVAEAIAFLLGPQASFIHGSVLFVDGGMD 247 >5TQV-A nrPDB Length = 233 Score = 114 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 53/204 (25%), Positives = 90/204 (44%), Gaps = 10/204 (4%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 MA + K V++ G RG+G VR + G V+ +D++ AL GA Sbjct: 1 MAHHHHHHMKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRA--LGAHAHA 58 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET-SAQGFRQLLELNLLGTY 119 D+TQ + + L + RLD V +G + P ET ++ F ++ N+ G Sbjct: 59 LDITQPEQIAALGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPM 116 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP---YVATKGAVTAMTKALALDESPYG 176 L + LP + ++G + +SS +G+I +A Y A+K A+ + + +L Sbjct: 117 QLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIASLQT--RH 174 Query: 177 VRVNCISPGNIWTPLWEELAALMP 200 + PG + T + AAL P Sbjct: 175 AACISLHPGWVRTDMGGAQAALDP 198 >2O2S-A nrPDB Length = 315 Score = 112 bits (280), Expect = 2e-25, Method: Composition-based stats. Identities = 65/300 (21%), Positives = 105/300 (35%), Gaps = 45/300 (15%) Query: 7 YAGKVVVVTGG--GRGIGAGIVRAFVNSGARVVI------------------CDKDESGG 46 G+ V G G G I + ++GARV + D+D Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 47 RALEQELPGAVFILCDVTQEDDV------------------KTLVSETIRRFGRLDCVVN 88 E G + + +DV K + + + G +D +V+ Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH 126 Query: 89 NAGHHPPPQRP-EETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIG 147 + + P +P ETS +G+ + +L + P + + G+ + +S L Sbjct: 127 SLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNE-GGSAVTLSYLAAERV 185 Query: 148 QAQA-VPYVATKGAVTAMTKALALDES-PYGVRVNCISPGNIWTPLWEELAALMPD--PR 203 + K A+ + T+ LA + YGVRVN IS G + + + Sbjct: 186 VPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFID 245 Query: 204 ATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRSTP 262 I PL R +VG AA+FL S A +G+ L V G SRS P Sbjct: 246 YAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQAVDSRSMP 305 >3U9L-A nrPDB Length = 324 Score = 111 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 57/216 (26%), Positives = 94/216 (43%), Gaps = 12/216 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA---------V 57 + K++++TG G G A +G RV +D G A E Sbjct: 3 MSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLR 62 Query: 58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 + DV + V + + I GR+D +++NAGH E + + F +L ++N+L Sbjct: 63 TLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMV-FGPAEAFTPEQFAELYDINVLS 121 Query: 118 TYTLTKLALPYLRKSQ-GNVINISSLVGAIGQAQA-VPYVATKGAVTAMTKALALDESPY 175 T + + ALP++R+ + G +I ISS A G PY A K A+ A+ A + S + Sbjct: 122 TQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRW 181 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGML 211 G+ + I PG + + +PD A E Sbjct: 182 GIETSIIVPGAFTSGTNHFAHSGVPDDHARQAEYEA 217 >1B15-A nrPDB Length = 254 Score = 111 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 53/220 (24%), Positives = 81/220 (36%), Gaps = 20/220 (9%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL----PGAVFI 59 K V+ GIG R V + VI D+ E+ E + F Sbjct: 1 MDLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFH 60 Query: 60 LCDVTQE-DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 DVT + K L+ + + +D ++N AG + + +N G Sbjct: 61 TYDVTVPVAESKKLLKKIFDQLKTVDILINGAGI---------LDDHQIERTIAINFTGL 111 Query: 119 YTLTKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESP 174 T L + K +G + NI S+ G Q Y A+K AV + T +LA Sbjct: 112 VNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPI 171 Query: 175 YGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQP 214 GV I+PG TPL + + D + E +L+ P Sbjct: 172 TGVTAYSINPGITRTPLVHTFNSWL-DVEPRVAELLLSHP 210 >1ENP-A nrPDB Length = 312 Score = 111 bits (278), Expect = 3e-25, Method: Composition-based stats. Identities = 53/286 (18%), Positives = 96/286 (33%), Gaps = 47/286 (16%) Query: 7 YAGKVVVVTGGG--RGIGAGIVRAFVNSGARVVI------------------CDKDESGG 46 GK + G G G + ++ +GA +++ D+ Sbjct: 16 LRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLP 75 Query: 47 RALEQELPGAVFILCDVTQEDDV------------------KTLVSETIRRFGRLDCVVN 88 E+ + +DV + + FG +D +V+ Sbjct: 76 DGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILVH 135 Query: 89 NAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIG 147 + + P +P ETS +G+ + + +L LP + ++ +++ + Sbjct: 136 SLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIMNPGGASI-SLTYIASERI 194 Query: 148 QAQAVP-YVATKGAVTAMTKALALDESPY-GVRVNCISPGNIWTPLWEELAALMPDPRAT 205 + K A+ + T+ LA + +RVN IS G PL A + Sbjct: 195 IPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAG----PLGSRAAKAIGFIDTM 250 Query: 206 IREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAE 250 I P+ + EVG AA FL S A+ TG + V G Sbjct: 251 IEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLN 296 >5LCX-A nrPDB Length = 316 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 61/304 (20%), Positives = 87/304 (28%), Gaps = 94/304 (30%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA---- 56 MA RY +VTG +GIG I R G V++ ++E G Q+L Sbjct: 3 MAEVQRY----ALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVS 58 Query: 57 ----VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHH-----PPPQRPEETSAQGF 107 VF DVT V + +FG+LD +VNNAG E F Sbjct: 59 ENRLVFHQLDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADF 118 Query: 108 RQLLE-------------------------------LNLLGTYTLTKLALPYLRKSQG-N 135 + L N G LT+ +P L+ S Sbjct: 119 KALQALEAGAKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPR 178 Query: 136 VINI-------------------------------------------SSLVGAIGQAQAV 152 ++N+ L + Sbjct: 179 IVNVSSSFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFA 238 Query: 153 PYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLA 212 +K A+ A TK A + R+N I PG T + L A + + Sbjct: 239 AERVSKAALNAYTKIAAKKYPSF--RINAICPGYAKTDITFHAGPLSVAEAAQVPVKLAL 296 Query: 213 QPLG 216 P G Sbjct: 297 LPDG 300 >1MG5-A nrPDB Length = 255 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 50/218 (22%), Positives = 79/218 (36%), Gaps = 20/218 (9%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG----AVFILC 61 K V+ G GIG + + + +VI D+ E+ E + F Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPY 63 Query: 62 DVTQE-DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 DVT + L+ + +D ++N AG + + +N G Sbjct: 64 DVTVPIAETTKLLKTIFAQLKTVDVLINGAGI---------LDDHQIERTIAVNYTGLVN 114 Query: 121 LTKLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 T L + K +G + NI S+ G Q Y TK AV T +LA G Sbjct: 115 TTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITG 174 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQP 214 V ++PG T L + + + D + E +LA P Sbjct: 175 VTAYTVNPGITRTTLVHKFNSWL-DVEPQVAEKLLAHP 211 >2NTV-A nrPDB Length = 268 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 57/263 (21%), Positives = 97/263 (36%), Gaps = 21/263 (7%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGG-RALEQELP-GAVFILCD 62 GK ++V+G I I + +GA++V+ D + + LP A I D Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIELD 63 Query: 63 VTQEDDVKTLVSETIRRFG---RLDCVVNNAGHHPPPQR----PEETSAQGFRQLLELNL 115 V E+ + TL G +LD VV++ G P + + + + ++ Sbjct: 64 VQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGIHIST 123 Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 +L K L + S G+++ + K A+ ++ + +A + Y Sbjct: 124 YSYASLAKALL-LIMNSGGSIVGMD-FDPTRAMPAYNWMTVAKSALESVNRFVAREAGKY 181 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGML------AQPLGR-MGQPAEVGAAA 228 GVR N ++ G I T + A + +L P+G M P V Sbjct: 182 GVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKTV 241 Query: 229 VFLASE-ANFCTGIELLVTGGAE 250 L SE TG + GGA Sbjct: 242 CALLSEWLPATTGSIIYADGGAS 264 >3F4B-A nrPDB Length = 323 Score = 99.2 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 50/299 (16%), Positives = 99/299 (33%), Gaps = 61/299 (20%) Query: 16 GGGRGIGAGIVRAFVNSGARVV-------------------------ICDKDESGGRALE 50 G G G GI + +V+ I + + + L+ Sbjct: 16 GDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKRMQILD 75 Query: 51 QELPGAVFILCDVTQED-------------DVKTLVSETIRRFGRLDCVVNNAGHHPPPQ 97 A F D ED ++ + + ++G++ +V++ + Q Sbjct: 76 VLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVHSLANGREVQ 135 Query: 98 R-PEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP-YV 155 + +TS G+ + + +L K ++ S G+V++++ Sbjct: 136 KSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM-NSGGSVVSLTYQASQKVVPGYGGGMS 194 Query: 156 ATKGAVTAMTKALALDESP-YGVRVNCISPGNIWTPLWEELA------------------ 196 + K A+ + T+ LA Y +R+N IS G + + + Sbjct: 195 SAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQKNNMNSSGETDK 254 Query: 197 ALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAELGYG 254 I PL + +VG+ A FL S E++ TG + V G + +G Sbjct: 255 QNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIYVDNGLNIMFG 313 >4OYR-A nrPDB Length = 289 Score = 95.7 bits (237), Expect = 2e-20, Method: Composition-based stats. Identities = 53/263 (20%), Positives = 95/263 (36%), Gaps = 21/263 (7%) Query: 7 YAGKVVVVTG--GGRGIGAGIVRAFVNSGARVVICDKDESGG-RALEQELP-GAVFILCD 62 GK ++V+G I I R GA++V+ D + + LP A + D Sbjct: 25 LDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELD 84 Query: 63 VTQEDDVKTLVSETIRRFG---RLDCVVNNAGHHPPPQR----PEETSAQGFRQLLELNL 115 V E+ + +L G +LD VV++ G P + + + ++ Sbjct: 85 VQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISA 144 Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPY 175 ++ K LP + G+++ + + K A+ ++ + +A + Y Sbjct: 145 YSYASMAKALLPIM-NPGGSIVGMD-FDPSRAMPAYNWMTVAKSALESVNRFVAREAGKY 202 Query: 176 GVRVNCISPGNIWTPLWEELAALMPDPRATIREGML------AQPLGR-MGQPAEVGAAA 228 GVR N ++ G I T + A + +L P+G M V Sbjct: 203 GVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTV 262 Query: 229 VFLASE-ANFCTGIELLVTGGAE 250 L S+ TG + GGA Sbjct: 263 CALLSDWLPATTGDIIYADGGAH 285 >5WQO-A nrPDB Length = 234 Score = 95.3 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 48/213 (22%), Positives = 87/213 (40%), Gaps = 11/213 (5%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKD---ESGGRALEQELPGAV-FILCDVTQED 67 V++ G RGIG G+ AF+ GA+V + G +AL + + + D+ Q D Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHH-PPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + + R R+D ++ NAG + P Q E A+ QL N + L + Sbjct: 69 CAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARALS 126 Query: 127 PYLRKSQGNVINISSLVGAIG---QAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 + G V +SS + ++ A Y A+K A+ ++ ++ + + + Sbjct: 127 GRV-SRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLLH 185 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLG 216 PG + T + + A L + A + G Sbjct: 186 PGWVRTEMGGDSAPLSVEESAAGLVAAVEDAAG 218 >2PTG-A nrPDB Length = 319 Score = 94.9 bits (235), Expect = 3e-20, Method: Composition-based stats. Identities = 60/314 (19%), Positives = 104/314 (33%), Gaps = 59/314 (18%) Query: 7 YAGKVVVVTGG--GRGIGAGIVRAFVNSGARVVI-----------------------CDK 41 GK V G G G I + +GARV++ Sbjct: 7 LRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 42 DESGGRALEQELPGAVFILCD------------------VTQED--------DVKTLVSE 75 E + + V ++ D V+ + + Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEA 126 Query: 76 TIRRFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG 134 G++D +V++ + P +P +TS +G+ + + +L + LP + K G Sbjct: 127 VRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLM-KEGG 185 Query: 135 NVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDESP-YGVRVNCISPGNIWTPLW 192 + + +S + + K A+ + + LA + VRVNCIS G + + Sbjct: 186 SALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSRAA 245 Query: 193 EELAALMPD--PRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGA 249 + I PL + + +VG AA+FL S A TG L V G Sbjct: 246 SAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDNGL 305 Query: 250 E-LGYGCKASRSTP 262 +G + TP Sbjct: 306 HAMGQALDSKSLTP 319 >4Z3K-A nrPDB Length = 275 Score = 88.4 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 22/212 (10%) Query: 11 VVVVTGGGRGIGA---GIVRAFVNSGARVVICDKDESGGRALEQELPG------AVFILC 61 V ++TG RG G ++ + ++ G+ +V+ +++ R LE EL V + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 62 DVTQEDDVKTLVSETIRR-----FGRLDCVVNNAGHHPPP--QRPEETSAQGFRQLLELN 114 D+ E ++ L+ RL ++NNAG + + + LN Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 141 Query: 115 LLGTYTLTKLALPYLRKSQG---NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD 171 L LT L S G V+NISSL Y A K A + + LAL+ Sbjct: 142 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 201 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPR 203 E VRV +PG + T + + DP Sbjct: 202 EP--NVRVLNYAPGPLDTDMQQLARETSVDPD 231 >4HWK-A nrPDB Length = 288 Score = 88.4 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 22/212 (10%) Query: 11 VVVVTGGGRGIGA---GIVRAFVNSGARVVICDKDESGGRALEQELPG------AVFILC 61 V ++TG RG G ++ + ++ G+ +V+ +++ R LE EL V + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 62 DVTQEDDVKTLVSETIRR-----FGRLDCVVNNAGHHPPP--QRPEETSAQGFRQLLELN 114 D+ E ++ L+ RL ++NNAG + + + LN Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 115 LLGTYTLTKLALPYLRKSQG---NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD 171 L LT L S G V+NISSL Y A K A + + LAL+ Sbjct: 155 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 214 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPR 203 E VRV +PG + T + + DP Sbjct: 215 EP--NVRVLNYAPGPLDTDMQQLARETSVDPD 244 >1OAA-A nrPDB Length = 259 Score = 87.2 bits (215), Expect = 6e-18, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 76/212 (35%), Gaps = 22/212 (10%) Query: 11 VVVVTGGGRGIGAGIVRAFVNS---GARVVICDKDESGGRALEQELP------GAVFILC 61 V V+TG RG G + G+ +++ + ES R L++EL V Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 62 DVTQEDDVKTLVSETIRR-----FGRLDCVVNNAGHHPPP--QRPEETSAQGFRQLLELN 114 D+ E V+ L+S RL ++NNA LN Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 115 LLGTYTLTKLALPYLRKSQG---NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALD 171 L LT L + S G V+NISSL Y A K A + + LA + Sbjct: 127 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 172 ESPYGVRVNCISPGNIWTPLWEELAALMPDPR 203 E VRV +PG + + + DP Sbjct: 187 EPS--VRVLSYAPGPLDNDMQQLARETSKDPE 216 >2O2Y-A nrPDB Length = 349 Score = 84.9 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 40/230 (17%), Positives = 81/230 (35%), Gaps = 47/230 (20%) Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQR-PEETSAQGFRQLLELNLLGTYTLTKLA 125 +DV L+ + ++G+++ +V++ + Q+ TS +G+ L + +L K Sbjct: 113 EDVANLIHQ---KYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYF 169 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDESP-YGVRVNCIS 183 + + K Q ++I+++ + K A+ + T+ LA Y +R+N IS Sbjct: 170 VNIM-KPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTIS 228 Query: 184 PGNIWTPLWEELAAL---------------------------------------MPDPRA 204 G + + + L Sbjct: 229 AGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFIDY 288 Query: 205 TIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAELGY 253 I PL + ++G+ A FL S E+ TG + V G + + Sbjct: 289 AIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMF 338 >3ORF-A nrPDB Length = 251 Score = 61.0 bits (147), Expect = 5e-10, Method: Composition-based stats. Identities = 34/190 (17%), Positives = 73/190 (38%), Gaps = 11/190 (5%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + K ++V GG +GA +V+ F + + D E+ + + E Sbjct: 20 HMSKNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKDSG--------E 71 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 +++K+++ + + ++D V AG + + + ++++NL + + Sbjct: 72 EEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIGA 131 Query: 127 PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDES--PYGVRVNCISP 184 L + G + + + + Y ATK A + K LA + P G I P Sbjct: 132 KLLNQ-GGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGILP 190 Query: 185 GNIWTPLWEE 194 + TP + Sbjct: 191 VTLDTPTNRK 200 >3SLK-A nrPDB Length = 795 Score = 61.0 bits (147), Expect = 6e-10, Method: Composition-based stats. Identities = 42/187 (22%), Positives = 72/187 (38%), Gaps = 27/187 (14%) Query: 11 VVVVTGGGRGIGAGIVRAFV-NSGAR-VVICDKD---ESGGRALEQEL----PGAVFILC 61 V+VTGG +GA + R V G R +V+ + SG L +L C Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 DV + + +++ L VV+ AG E + + Q+L + G L Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVS-ESLTVERLDQVLRPKVDGARNL 649 Query: 122 TKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAM----------TKALALD 171 +L P + ++ SS+ G +G Y A + A+ T++LA Sbjct: 650 LELIDPDV-----ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLAWG 704 Query: 172 -ESPYGV 177 + +G+ Sbjct: 705 PWAEHGM 711 >4LIS-A nrPDB Length = 371 Score = 59.9 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 56/172 (32%), Gaps = 34/172 (19%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICD-----KDESGGRALEQELPGAVFILCDVTQE 66 V+VTGG IG+ A + +G +VV+ D E+ R A F DVT E Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + +D V++ A + S + +N+ GT L Sbjct: 66 ----AAFDKVFEAHPDIDSVIHFAALKAVGE-----SGEKPLDYYHVNVYGTI----CLL 112 Query: 127 PYLRKSQGNVINISSLVGAIGQA----------------QAVPYVATKGAVT 162 + + I SS G A PY TK A+ Sbjct: 113 RSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >2PK3-A nrPDB Length = 321 Score = 56.4 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 80/259 (30%), Gaps = 44/259 (16%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 ++TG +G + V ++ +LP I D+ VK Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEA------KLPNVEMISLDIMDSQRVKK 68 Query: 72 LVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK 131 ++S+ + D + + A + S + N+ GT + L +R Sbjct: 69 VISDI-----KPDYIFHLAAKSS-----VKDSWLNKKGTFSTNVFGTLHV----LDAVRD 114 Query: 132 SQG--NVINISS-------------LVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 S ++ I S + PY +K +V + + Sbjct: 115 SNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDI 174 Query: 177 V---RVNCISPGNIWTPLWEELAALMPDPRATIREGMLA----QPLGRMGQPAEVGAAAV 229 + N I PG + ++ A + D +E ++ + + ++ A Sbjct: 175 IHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAY- 233 Query: 230 FLASEANFCTGIELLVTGG 248 +L S+ TG V G Sbjct: 234 WLLSQYG-KTGDVYNVCSG 251 >2Q1W-A nrPDB Length = 333 Score = 54.9 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 64/195 (32%), Gaps = 30/195 (15%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 K V +TG IG+ I + G +VV D +G R ++ P F+ + V Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSIADHALV 81 Query: 70 KTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 L+ + D VV+ A + P + N +G + + A Sbjct: 82 NQLIGDLQ-----PDAVVHTAASYKDP--------DDWYNDTLTNCVGGSNVVQAAK--- 125 Query: 130 RKSQGNVI----NISSLV---------GAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 + + G + + V Y +K A + LD + Sbjct: 126 KNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGLDFVTFR 185 Query: 177 VRVNCISPGNIWTPL 191 + N + P N+ PL Sbjct: 186 L-ANVVGPRNVSGPL 199 >1OOE-A nrPDB Length = 236 Score = 54.9 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 38/217 (17%), Positives = 76/217 (35%), Gaps = 12/217 (5%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 +GKV +V GG +G+ I+ F +G V+ D + + + + + + Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLSAN------DQADSNILVDGNKNWTE 55 Query: 68 DVKTLVSETIRRFGR--LDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 ++++ +T +D V AG + + +++ ++ + KLA Sbjct: 56 QEQSILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSSAIAAKLA 115 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALAL--DESPYGVRVNCIS 183 +L K G + + + Y K AV +T +LA P V I Sbjct: 116 TTHL-KPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNSAVLTIM 174 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQ 220 P + TP+ + T + L + Sbjct: 175 PVTLDTPMNRKWMPNADHSSWTPLSFISEHLLKWTTE 211 >6BWL-A nrPDB Length = 328 Score = 53.3 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 77/266 (28%), Gaps = 46/266 (17%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICD----KDESGGRALEQELPGAVFILCDVTQE 66 ++VTGG IG +V+ + V I D + +L I D+ + Sbjct: 2 KILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDK 61 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 V L F + + S R E + +GT+ L + L Sbjct: 62 KLVAQLFEN--NSFDLCYHLAASINVQD--------SIDDARATFENDTIGTFNLLEQCL 111 Query: 127 PY----------LRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176 Y + + NI + A PY +K A M + Y Sbjct: 112 NYDVKMVFMSTCMVYDKAT--NIQGISELDPIKPASPYAGSKIAAENMVLSY---YYAYK 166 Query: 177 VRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQ---------PAEVGAA 227 + V I P N + P +++ I + PL G + Sbjct: 167 LPVVVIRPFNTYGP-FQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCADF 225 Query: 228 AV---FLASEANFC----TGIELLVT 246 V + A TG ++ + Sbjct: 226 VVAAGYSAKANGHIINAGTGQDISIN 251 >1VL0-A nrPDB Length = 292 Score = 51.4 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 51/169 (30%), Gaps = 42/169 (24%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 +++TG +G I + V+ D + D+T V Sbjct: 14 KILITGANGQLGREIQKQLKGKNVEVIPTDVQD-----------------LDITNVLAVN 56 Query: 71 TLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLR 130 +E + + V+N A H + + + ++N +G L A Sbjct: 57 KFFNE-----KKPNVVINCAAHTA-----VDKCEEQYDLAYKINAIGPKNLAAAAYSV-- 104 Query: 131 KSQGNVINISSLVGAIGQAQ-----------AVPYVATKGAVTAMTKAL 168 ++ IS+ G+A+ Y TK KAL Sbjct: 105 --GAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >3RFT-A nrPDB Length = 267 Score = 51.0 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 50/135 (37%), Gaps = 24/135 (17%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 A K ++VTG +G + A + + L+ P + CD+ Sbjct: 1 MAMKRLLVTGAAGQLGRVMRERLAPM-AEI----LRLADLSPLDPAGPNEECVQCDLADA 55 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 + V +V+ D +V+ G + F Q+L+ N++G Y L + A Sbjct: 56 NAVNAMVA-------GCDGIVHLGGISV---------EKPFEQILQGNIIGLYNLYEAAR 99 Query: 127 PYLRKSQGNVINISS 141 + Q ++ SS Sbjct: 100 AH---GQPRIVFASS 111 >1UDA-A nrPDB Length = 338 Score = 50.3 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 19/151 (12%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICD---KDESGGRALEQELPGAV--FILCDVTQE 66 V+VTGG IG+ + +G V+I D + + + L G F+ D+ E Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNE 62 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126 L++E + +D V++ AG + S Q + + N+ GT L Sbjct: 63 ----ALMTEILHDH-AIDTVIHFAGLKAVGE-----SVQKPLEYYDNNVNGTLRLISA-- 110 Query: 127 PYLRKSQGNVINISSLVGAIGQAQAVPYVAT 157 +R + SS G +PYV + Sbjct: 111 --MRAANVKNFIFSSSATVYGDNPKIPYVES 139 >1DIR-A nrPDB Length = 241 Score = 47.6 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 73/195 (37%), Gaps = 19/195 (9%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 + V+V GG +G+ V+AF V D E+ +E +V + + + Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVEN------EEASASVIVKMTDSFTE 59 Query: 68 DVKTLVSETIRRFG--RLD-CVVNN---AGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 + +E + G ++D + AG + + + ++Q + + + ++ Sbjct: 60 QADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLA 119 Query: 122 TKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALA--LDESPYGVRV 179 TK K G + + G + Y KGAV + ++LA P G Sbjct: 120 TKHL-----KEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAA 174 Query: 180 NCISPGNIWTPLWEE 194 + P + TP+ + Sbjct: 175 IAVLPVTLDTPMNRK 189 >2GN9-A nrPDB Length = 344 Score = 46.4 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 25/160 (15%), Positives = 53/160 (33%), Gaps = 22/160 (13%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRA-FVNSGA-RVVICDKDESGGRALEQEL--PGAVF 58 + +++TGG G VR + A ++++ +DE + E P F Sbjct: 15 HQNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRF 74 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 + DV + + + +D ++ A E + + ++ N++G Sbjct: 75 FIGDVRDLERLNYALE-------GVDICIHAAAL--KHVPIAEYNP---LECIKTNIMGA 122 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATK 158 + L + + +L Y ATK Sbjct: 123 SNVINACLKN------AISQVIALSTDKAANPINLYGATK 156 >1RKX-A nrPDB Length = 357 Score = 46.0 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 43/230 (18%), Positives = 72/230 (31%), Gaps = 31/230 (13%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL 60 M + + GK V VTG G + GA V +L + A + Sbjct: 1 MINNSFWQGKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVADGMQ 60 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 ++ D L+ + + V + A Q S + N++GT Sbjct: 61 SEIGDIRDQNKLLESIREF--QPEIVFHMAA-----QPLVRLSYSEPVETYSTNVMGTVY 113 Query: 121 LTKLALPYLRKSQG--NVINISS---------LVGAI---GQAQAVPYVATKGAVTAMTK 166 L L +R G V+NI+S + G PY +KG +T Sbjct: 114 L----LEAIRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTS 169 Query: 167 ALA------LDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGM 210 + + +G V + GN+ L ++PD + Sbjct: 170 SYRNSFFNPANYGQHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQ 219 >6GCS-E nrPDB Length = 375 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 57/161 (35%), Gaps = 23/161 (14%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQ--ELPGAVFILCDVTQ 65 G V G +G+ + G VV+ ++E R L+ +L F+ D+ Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREEMAKRHLKVTGDLGVVNFLEMDLRN 111 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + + V + D VVN G E + F ++++ G + + Sbjct: 112 LESIDEAVRHS-------DIVVNLIG--------REYETKNFNY-YDVHVEGARRIAEAV 155 Query: 126 LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 + + I++S+ I + TKG +TK Sbjct: 156 KKH---NIARYIHVSAFNAEIDSPSEFNH--TKGLGEQVTK 191 >1I3M-A nrPDB Length = 348 Score = 44.5 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 38/183 (20%), Positives = 58/183 (31%), Gaps = 38/183 (20%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICD-----------KDESGGRALEQELPGAVFI 59 V+VTGG IG+ V + +G V+ D ES R E F Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 D+ + ++ L + V++ AG + S Q +NL GT Sbjct: 64 EMDILDQGALQRLFKKY-----SFMAVIHFAGLKAMGE-----SVQKPLDYYRVNLTGTI 113 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQA-------------VPYVATKGAVTAMTK 166 L L ++ + SS G Q PY +K + M + Sbjct: 114 QL----LEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIR 169 Query: 167 ALA 169 L Sbjct: 170 DLC 172 >4R1T-A nrPDB Length = 337 Score = 44.1 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 40/221 (18%), Positives = 70/221 (31%), Gaps = 52/221 (23%) Query: 2 ATGTR-YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG-----GRALEQELPG 55 + G R +G+VV VTG G I + +V+ + G V ++ R LE Sbjct: 2 SHGMRSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKER 61 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 D+ ++ ++ D V + A P PE+ + Sbjct: 62 LTLCKADLLDYQSLREAIN-------GCDGVFHTA--SPVTDDPEQMVEPA--------V 104 Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVP---------------------Y 154 +GT + A + V+ SS+ P Y Sbjct: 105 IGTKNVINAAA---EANVRRVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWY 161 Query: 155 VATKGAVTAMTKALALDESP-YGVRVNCISPGNIWTPLWEE 194 K + + A +E+ GV + I+P + PL + Sbjct: 162 CYGKM----VAEQAAWEEAKEKGVDLVVINPVLVQGPLLQT 198 >2PZM-A nrPDB Length = 330 Score = 44.1 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 20/117 (17%), Positives = 45/117 (38%), Gaps = 13/117 (11%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 +++TGG +G+ ++ ++ G +++ D +G R + + G I VT ++ Sbjct: 23 ILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGLSVIEGSVTDAGLLER 82 Query: 72 LVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPY 128 VV++A + P + + N+ G+ + K A Sbjct: 83 AFDSFKPTH-----VVHSAAAYKDP--------DDWAEDAATNVQGSINVAKAASKA 126 >4G5H-A nrPDB Length = 363 Score = 44.1 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 65/163 (39%), Gaps = 21/163 (12%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPGA--VFI 59 + + K++++TGG G +++ F++S + + I +DE + ++ + F Sbjct: 19 SAMGFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFY 78 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 + DV V+T + + +D V + A P E + + N++GT Sbjct: 79 IGDVRDSQSVETAMRD-------VDYVFHAAALKQVPS-CEFFPVEAVK----TNIIGTE 126 Query: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVT 162 + + A+ K VI +S+ A +K + Sbjct: 127 NVLQSAIHQNVK---KVICLSTDKAAYPI---NAMGISKAMME 163 >3ENK-A nrPDB Length = 341 Score = 44.1 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 5/70 (7%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV-----FILCDVTQ 65 ++VTGG IG+ + G VVI D + R + F DV+ Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSD 66 Query: 66 EDDVKTLVSE 75 E + + Sbjct: 67 ERALARIFDA 76 >4J2O-A nrPDB Length = 363 Score = 43.7 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 33/233 (14%), Positives = 82/233 (35%), Gaps = 26/233 (11%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPGA--VFIL 60 G+ + KV+++TGG G +++ F+ + + + I +DE + ++ A F + Sbjct: 18 GSMFKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYI 77 Query: 61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFR--QLLELNLLGT 118 DV + + +D + + A ++ + F + ++ N+LGT Sbjct: 78 GDVRDYNSILNATR-------GVDYIYHAAA-------LKQVPSCEFHPMEAVKTNVLGT 123 Query: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 + + A+ K V+ +S+ +K + + A + + Sbjct: 124 ENVLEAAIQNHVK---RVVCLSTDKAVYPI---NAMGISKAMMEKVMVAKSRNLEGLDTV 177 Query: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGR-MGQPAEVGAAAVF 230 + GN+ + + R + + R M + ++ Sbjct: 178 ICGTRYGNVMASRGSVIPLFVDQIRQGKPLTITDPNMTRFMMTLEDAVDLVLY 230 >4PVC-A nrPDB Length = 342 Score = 42.5 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 46/141 (32%), Gaps = 9/141 (6%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 V V+G I IV + +V+ + + L + +V + Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 72 LVSETIRRFGR-LDCVVNNAGHHPPPQRPEETSAQGFRQLLELN-LLGTYTLTKLALPYL 129 ++ G+ + V++ A P + T ++ + +N + G K Y Sbjct: 63 AFDHVFQKHGKDIKIVLHTA----SPFCFDITDSERDLLIPAVNGVKGILHSIK---KYA 115 Query: 130 RKSQGNVINISSLVGAIGQAQ 150 S V+ SS A+ Sbjct: 116 ADSVERVVLTSSYAAVFDMAK 136 >3SXP-A nrPDB Length = 362 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 64/202 (31%), Gaps = 41/202 (20%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSG--ARVVICD-----------KDESGGRALEQEL 53 + +++TGG +G+ + F + A+VV+ D + S G Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 54 PGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLEL 113 I D+ D++ L D + + A +E +++ Sbjct: 68 FKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQEL-------VMKT 114 Query: 114 NLLGTYTLTKLALPYLRKSQGNVINISS--LVGAIGQAQAV--------PYVATKGAVTA 163 N L ++A R + VI SS + G V Y +K + Sbjct: 115 NYQAFLNLLEIA----RSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMDE 170 Query: 164 MTKALALDESPYGVR-VNCISP 184 + + D G+R N P Sbjct: 171 FVLSHSNDNVQVGLRYFNVYGP 192 >1Z45-A nrPDB Length = 699 Score = 42.2 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 39/182 (21%), Positives = 63/182 (34%), Gaps = 35/182 (19%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-----KDESGGRALEQELPGAVFILCD 62 K+V+VTGG IG+ V + +G V+ D +S R F D Sbjct: 10 TSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVD 69 Query: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122 + ++ + E ++D V++ AG + S Q + N+LGT L Sbjct: 70 LCDRKGLEKVFKEY-----KIDSVIHFAGLKAVGE-----STQIPLRYYHNNILGTVVL- 118 Query: 123 KLALPYLRKSQGNVINISSLVGAIGQA----------------QAVPYVATKGAVTAMTK 166 L +++ + SS G A PY TK A+ + Sbjct: 119 ---LELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILN 175 Query: 167 AL 168 L Sbjct: 176 DL 177 >2NNL-D nrPDB Length = 337 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 37/268 (13%), Positives = 75/268 (27%), Gaps = 56/268 (20%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQ--ELPGAVFI----LC 61 + V VTG IG+ +V + G V +D + + ++ +LP A Sbjct: 4 QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKA 63 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 D+ E + F H P E + ++++ + G + Sbjct: 64 DLADEGSFDEAIKGCTGVF-----------HVATPMDFESKDPE--NEVIKPTIEGMLGI 110 Query: 122 TKLALPYLRKSQGNVINISSLVGAIGQAQAVP----------------------YVATKG 159 K K+ ++ SS Q +P Y +K Sbjct: 111 MKSCAAA--KTVRRLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKT 168 Query: 160 AVTAMTKALALDESPYGVRVNCISPG-----NIWTPLWEELAALMPDPRATIREGMLAQP 214 A + + I P I + + L + + + Sbjct: 169 LAEQAAWKYAKE---NNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIR- 224 Query: 215 LGRMGQPAEVGAAAVFLA----SEANFC 238 G+ ++ A ++L +E + Sbjct: 225 QGQFVHLDDLCNAHIYLFENPKAEGRYI 252 >2EXX-A nrPDB Length = 306 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSG-ARVVICDKDESGGRALEQELPGAVFILC 61 G K+VVV GG G + R + G +V + ++ A E L GA + Sbjct: 5 AGLMVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQG 64 Query: 62 DVTQEDDVKTLVSETIRRF 80 D + ++ ++ F Sbjct: 65 DQDDQVIMELALNGAYATF 83 >1BXK-A nrPDB Length = 355 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 40/183 (21%), Positives = 70/183 (38%), Gaps = 34/183 (18%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNS--GARVVI---CDKDESGGRALEQELPGAVFILCDVT 64 + +++TGG IG+ +VR +N A VV+ A + F D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 ++ + +E DCV++ A + + S G +E N++GTYTL + Sbjct: 62 DRAELARVFTEHQ-----PDCVMHLAA-----ESHVDRSIDGPAAFIETNIVGTYTLLEA 111 Query: 125 ALPYL------RKSQGNV--INISSLVG-----------AIGQAQAVPYVATKGAVTAMT 165 A Y +KS I+ + G A + PY A+K + + Sbjct: 112 ARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLV 171 Query: 166 KAL 168 +A Sbjct: 172 RAW 174 >1KEU-A nrPDB Length = 361 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 33/203 (16%), Positives = 65/203 (32%), Gaps = 42/203 (20%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVI-----CDKDESGGRALEQELPGAVFILCDVTQ 65 +++TGG IG+ +VR + + V+ + E F D+ Sbjct: 2 KILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICD 61 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 ++ + + A H + + S G +E N++GTY L ++A Sbjct: 62 SAEITRIFEQYQPD----------AVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVA 111 Query: 126 LPYL------RKSQGNV--INISSLVGAIGQA-------------------QAVPYVATK 158 Y +K+ I+ + G + + PY A+K Sbjct: 112 RKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASK 171 Query: 159 GAVTAMTKALALDESPYGVRVNC 181 + + +A + NC Sbjct: 172 ASSDHLVRAWRRTYGLPTIVTNC 194 >5N2I-A nrPDB Length = 232 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 24/55 (43%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 +G + V GG G G+ R F +G V++ + +A+ EL + + Sbjct: 17 VSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRG 71 >5F5N-A nrPDB Length = 289 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDD 68 + ++VTG G VRA + G V +D A G + D+ + Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQAS 60 Query: 69 VKTLVSETIRRF 80 ++ +++ F Sbjct: 61 LRAAMADVHGVF 72 >2HUN-A nrPDB Length = 336 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 31/173 (17%) Query: 13 VVTGGGRGIGAGIVRAFVNSG--ARVVICDK-----DESGGRALEQELPGAVFILCDVTQ 65 +VTGG IG+ +R + V+ DK + + + LE + P F+ DV Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDD-PRYTFVKGDVAD 65 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL---T 122 + VK LV ++D VV+ A + S + F L N++GTYTL Sbjct: 66 YELVKELVR-------KVDGVVHLAAESHVDRSIS--SPEIF---LHSNVIGTYTLLESI 113 Query: 123 KLALPYLR-------KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKAL 168 + P +R + G+++ S + PY ATK A + Sbjct: 114 RRENPEVRFVHVSTDEVYGDILK-GSFTENDRLMPSSPYSATKAASDMLVLGW 165 >5B6K-A nrPDB Length = 366 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 26/161 (16%), Positives = 53/161 (32%), Gaps = 18/161 (11%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 V V+G I +VR ++ +V+ + G L+ + ++ ++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 71 TLVSETIRRFGR-LDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 T + G+ + V++ A P T + + +N TK L + Sbjct: 83 TAFDHVFEKHGKDIKVVLHTA----SPFHFNTTDIEKDLLIPAVN------GTKGILESI 132 Query: 130 RKSQG----NVINISSLVGAIGQAQAVPYVATKGAVTAMTK 166 +K V+ SS V K + +T+ Sbjct: 133 KKYAAQTVERVVVTSSFAA---NTSTVDMFYAKDSSKTITE 170 >3HFS-A nrPDB Length = 338 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 48/151 (31%), Gaps = 20/151 (13%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE-----QELPG 55 MAT K V GG + + +V+ + G V +D + + QEL Sbjct: 1 MATQHPIGKKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGD 60 Query: 56 AVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 D+T E + ++ D V + A P E+ + ++ Sbjct: 61 LKIFRADLTDELSFEAPIA-------GCDFVFHVA--TPVHFASEDPENDMIKPAIQ--- 108 Query: 116 LGTYTLTKLALPYLRKSQGNVINISSLVGAI 146 G + K KS VI SS Sbjct: 109 -GVVNVMKACTRA--KSVKRVILTSSAAAVT 136 >5K1S-A nrPDB Length = 362 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 27/52 (51%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI 59 AG+ V++TG G+G V+ GARV+ E+ +AL++ V + Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIV 234 >1R66-A nrPDB Length = 337 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 60/177 (33%), Gaps = 38/177 (21%) Query: 13 VVTGGGRGIGAGIVRAFVNSGA-------RVVI----CDKDESGGRALEQELPGAVFILC 61 +VTGG IG+ VR + +GA V++ A P F+ Sbjct: 4 LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHG 62 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL 121 D+ R +D +V+ A + + S G E N+ GT TL Sbjct: 63 DIRDA-------GLLARELRGVDAIVHFAA-----ESHVDRSIAGASVFTETNVQGTQTL 110 Query: 122 TKLALPYLRKSQGNVINIS-----------SLVGAIGQAQAVPYVATKGAVTAMTKA 167 + A+ G V+++S S + PY A+K + +A Sbjct: 111 LQCAVDA---GVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARA 164 >4KTT-E nrPDB Length = 327 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 42/133 (31%), Gaps = 24/133 (18%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDD 68 + V+VTG +G + + F + V C + + F ++ Sbjct: 21 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK----------FEQVNLLD--- 67 Query: 69 VKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPY 128 V I F + +V+ A P + +LN+ + L K A Sbjct: 68 -SNAVHHIIHDF-QPHVIVHCAAERRP-----DVVENQPDAASQLNVDASGNLAKEAA-- 118 Query: 129 LRKSQGNVINISS 141 +I ISS Sbjct: 119 --AVGAFLIYISS 129 >5YWN-A nrPDB Length = 334 Score = 38.7 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 49/137 (35%), Gaps = 15/137 (10%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 V V+G + I+ ++ G +VV + E G L++ V + + K Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYE--VVKVLEQKG 62 Query: 72 LVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK 131 E +++ + ++ A P E+T + L+ TK L ++ Sbjct: 63 AFDEALKKHPEVTIFLHTA--SPVTFEVEDTEKEI--------LIPAINGTKYVLQSIKD 112 Query: 132 ---SQGNVINISSLVGA 145 V+ SS+V Sbjct: 113 VAPQITRVVYTSSVVAM 129 >1OC2-A nrPDB Length = 348 Score = 38.3 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 17/124 (13%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE---SGGRALEQELPG--AVFILCDVT 64 K ++VTGG IG+ V N+ V + D+ +G +A + + G ++ D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 + V L ++ D +V+ A + S + N +GTYTL + Sbjct: 65 DAELVDKLAAKA-------DAIVHYAAESHNDNSLNDPSP-----FIHTNFIGTYTLLEA 112 Query: 125 ALPY 128 A Y Sbjct: 113 ARKY 116 >3OND-A nrPDB Length = 488 Score = 37.9 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 AT AGKV VV G G +G G A +GARV++ + D E + + Sbjct: 258 ATDVMIAGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLE- 315 Query: 62 DVTQEDDV 69 DV E D+ Sbjct: 316 DVVSEADI 323 >3NJ4-A nrPDB Length = 435 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 53/148 (35%), Gaps = 22/148 (14%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 AT AGKV VV G G +G G +A GARV+I + D AL+ + G Sbjct: 209 ATDVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEID--PINALQAAMEGYEVTTM 265 Query: 62 D---------VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLE 112 D VT + ++ + D +V N GH + + ++ Sbjct: 266 DEACQEGNIFVTTTGCIDIILGRHFEQMKD-DAIVCNIGHFDVEIDVKWLNENAVEKV-- 322 Query: 113 LNLLGTYTLTKLALPYLRKSQGNVINIS 140 + Y K+ +I ++ Sbjct: 323 -------NIKPQVDRYRLKNGRRIILLA 343 >1LU9-A nrPDB Length = 287 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 23/71 (32%), Gaps = 2/71 (2%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 A G GK VV G +G GA VV+C + +A + Sbjct: 112 AAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKR--FKV 169 Query: 62 DVTQEDDVKTL 72 +VT + Sbjct: 170 NVTAAETADDA 180 >3N58-A nrPDB Length = 464 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 61/183 (33%), Gaps = 29/183 (15%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCD 62 T AGKV VV G G +G G ++ +GARV + + D AL+ + G + D Sbjct: 241 TDVMMAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVD--PICALQAAMDGFEVVTLD 297 Query: 63 VTQEDDVKTLVSETIRRFGRLDC-------------VVNNAGHHPPPQRPEETSAQGFRQ 109 D + + G D +V N GH + + Sbjct: 298 -----DAASTADIVVTTTGNKDVITIDHMRKMKDMCIVGNIGHFDNEIQVAALRNLKW-- 350 Query: 110 LLELNLLGTYTLTKL--ALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGA-VTAMTK 166 N+ L + + S+G ++N+ + G + + + T+ Sbjct: 351 ---TNVKPQVDLIEFPDGKRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLGQIELFTR 407 Query: 167 ALA 169 A Sbjct: 408 TDA 410 >2C20-A nrPDB Length = 330 Score = 37.5 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 2/64 (3%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 +++ GG IG+ V+ V+ G VV+ D ++G E GA F D+ + ++ Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITE--GAKFYNGDLRDKAFLRD 61 Query: 72 LVSE 75 + ++ Sbjct: 62 VFTQ 65 >1GY8-A nrPDB Length = 397 Score = 37.5 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 41/207 (19%), Positives = 62/207 (29%), Gaps = 54/207 (26%) Query: 12 VVVTGGGRGIGAGIVRAFVNS-GARVVICD-------------KDESGGRALEQELP--- 54 V+V GG IG+ VRA + VVI D E+ R L+Q Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 55 -----GAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQ 109 A + DV ED ++ R G +D VV+ + + + Sbjct: 65 PWADRYAALEVGDVRNED----FLNGVFTRHGPIDAVVHMCAFLAVGESVRDP-----LK 115 Query: 110 LLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQA------------------ 151 + N++G L + L +I SS G Sbjct: 116 YYDNNVVGILRLLQA---MLLHKCDKIIF-SSSAAIFGNPTMGSVSTNAEPIDINAKKSP 171 Query: 152 -VPYVATKGAVTAMTKALALDESPYGV 177 PY +K M + A G+ Sbjct: 172 ESPYGESKLIAERMIRDCAEAYGIKGI 198 >6ACF-A nrPDB Length = 367 Score = 36.8 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 1/57 (1%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDV 63 GKVV V G G + + R GA++++ D ++ +E D+ Sbjct: 171 LEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDI 226 >3LK7-A nrPDB Length = 451 Score = 36.4 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 17/40 (42%), Gaps = 1/40 (2%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICD 40 M T T + K V+V G R G R GA V + D Sbjct: 1 MKTITTFENKKVLVLGLARS-GEAAARLLAKLGAIVTVND 39 >2C54-A nrPDB Length = 379 Score = 36.4 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 43/112 (38%), Gaps = 13/112 (11%) Query: 14 VTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLV 73 +TG G I + I R + G V+ D ++ + +++ F L D+ ++ Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKNEH--MTEDMFCDEFHLVDL-------RVM 84 Query: 74 SETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 ++ +D V N A + + ++ N + ++ + + A Sbjct: 85 ENCLKVTEGVDHVFNLAADMGGMGFIQSNHSV----IMYNNTMISFNMIEAA 132 >5INT-A nrPDB Length = 220 Score = 36.0 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 43/131 (32%), Gaps = 33/131 (25%) Query: 4 GTRYAGKVVVVTGG---------------GRG-IGAGIVRAFVNSGARVVICDKDESGGR 47 GK +++T G G +G I VN GA V++ Sbjct: 1 SNALQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS------- 53 Query: 48 ALEQELPGAVFILCDVT--QEDDVKTLVSETIRRFGRLDCVVNNAGHH---PPPQRPEET 102 P A+ VT Q + + ++ I+ + +D V+ A P + Sbjct: 54 -----GPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVADYRPKYVHDNKM 108 Query: 103 SAQGFRQLLEL 113 + ++EL Sbjct: 109 KKKNGDAVIEL 119 >4EJ6-A nrPDB Length = 370 Score = 36.0 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 3/86 (3%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 AG V + GGG IG V+ +GA VI ++ R L +E+ + D + D Sbjct: 182 AGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATV--DPSAGD 238 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHH 93 V+ + G +D V+ AG Sbjct: 239 VVEAIAGPVGLVPGGVDVVIECAGVA 264 >6G2J-P nrPDB Length = 377 Score = 36.0 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 43/116 (37%), Gaps = 17/116 (14%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVI---CDKDESGGRALEQELPGAVFI 59 + +G V V G +G +V G++V+I CD + L +L F+ Sbjct: 47 GRSSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQLTFL 106 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNL 115 D +D ++ V + + V+N G ET F + +N+ Sbjct: 107 EWDARDKDSIRKAVQHS-------NVVINLIGREW------ETRNFDFEDVF-VNI 148 >3SC6-A nrPDB Length = 287 Score = 36.0 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 51/168 (30%), Gaps = 42/168 (25%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 V++TG +G + + DK L D+T V+ Sbjct: 8 VIITGANGQLGKQLQEELNPEEYDIYPFDKK-----------------LLDITNISQVQQ 50 Query: 72 LVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK 131 +V E R +++ A + Q +E +N +G + +A + Sbjct: 51 VVQEI-----RPHIIIHCAAYTKVDQAEKER-----DLAYVINAIGARNVA-VASQLV-- 97 Query: 132 SQGNVINISSLVGAIG-----------QAQAVPYVATKGAVTAMTKAL 168 ++ IS+ G A Y A+K A K L Sbjct: 98 -GAKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >4K28-A nrPDB Length = 269 Score = 35.6 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSG-ARVVICDKDESGGRALEQELPGA 56 AGK +V G G G+G+ I A +G A + +CD + A+ + L Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNG 172 >3X2F-A nrPDB Length = 411 Score = 34.8 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 59/163 (36%), Gaps = 31/163 (19%) Query: 1 MATGTRY-AGKVVVVTGGGRG-IGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF 58 M AGK VVV G G G GI GARV++ + D +A+E + G Sbjct: 188 MRNTNLLVAGKNVVV--AGYGWCGRGIALRAAGLGARVIVTEVD--PVKAVEAIMDGFTV 243 Query: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCV-------------VNNAGHHP---PPQRPEET 102 + + + I G D + + NAGH P + EE Sbjct: 244 MPM-----KEAVKIADFVITASGNTDVLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEI 298 Query: 103 SAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGA 145 + + F N+ G + ++G ++N+++ G Sbjct: 299 AVEKFEA--RPNVTGYTL--ENGKTVFLLAEGRLVNLAAGDGH 337 >1YB5-A nrPDB Length = 351 Score = 34.8 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 5/80 (6%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 AG+ V+V G G+G + G +++ E G + + Q VF +V D Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYID 229 Query: 68 DVKTLVSETIRRFGRLDCVV 87 +K V E +D ++ Sbjct: 230 KIKKYVGE-----KGIDIII 244 >6BII-A nrPDB Length = 333 Score = 34.8 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 42/118 (35%), Gaps = 12/118 (10%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA---------LEQ 51 M G GK + + G GR IG I + G R++ + LE+ Sbjct: 142 MFLGYDVYGKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARSRKPEAEKELGAEFKPLEE 200 Query: 52 ELPGAVFILCDVTQEDDVKTLV-SETIRRFGRLDCVVNNA-GHHPPPQRPEETSAQGF 107 L + F++ V + ++ E +R +VN A G + +G+ Sbjct: 201 LLRESDFVVLAVPLTKETYHMINEERLRLMKPTAVLVNVARGKVVDTKALIRALKEGW 258 >1O89-A nrPDB Length = 345 Score = 34.8 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCD 62 +VVTG G+G+ V G +VV ES L + L + + D Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYL-KSLGASRVLPRD 220 >3H9U-A nrPDB Length = 436 Score = 34.5 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 34/151 (22%), Positives = 54/151 (35%), Gaps = 10/151 (6%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 AT AGK V G G +G G A GARVV+ + D E + + Sbjct: 204 ATDVMIAGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVE- 261 Query: 62 DVTQEDDVKTLVSE-----TIRRFGRL--DCVVNNAGHHPPPQRPEETSAQGFRQLLELN 114 DV +E + + T F R+ D +V N GH + A ++ E+ Sbjct: 262 DVVEEAHIFVTTTGNDDIITSEHFPRMRDDAIVCNIGHFDTEIQVAWLKANAKERV-EVK 320 Query: 115 LLGTYTLTKLALPYLRKSQGNVINISSLVGA 145 + ++G ++N+ G Sbjct: 321 PQVDRYTMANGRHIILLAEGRLVNLGCASGH 351 >2GGS-A nrPDB Length = 273 Score = 34.5 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 15/112 (13%), Positives = 34/112 (30%), Gaps = 21/112 (18%) Query: 13 VVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTL 72 ++TG +G + R V+ E+ G D+T ++ Sbjct: 4 LITGASGQLGIELSRLLSER-HEVIKVYNSS--------EIQG--GYKLDLTDFPRLEDF 52 Query: 73 VSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 + + R D ++N A + E + ++N + + Sbjct: 53 IIK-----KRPDVIINAAAMTDVDKCEIEK-----EKAYKINAEAVRHIVRA 94 >4DGK-A nrPDB Length = 501 Score = 34.5 bits (78), Expect = 0.055, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 14 VTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQELPGAVFILC--DVTQEDDVK 70 V G G G G + +G V++ + +D+ GGRA E G F +T ++ Sbjct: 6 VIGAGFG-GLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAIE 64 Query: 71 TLVSETIRRFG 81 L + ++ Sbjct: 65 ELFALAGKQLK 75 >1ZZE-A nrPDB Length = 342 Score = 34.5 bits (78), Expect = 0.057, Method: Composition-based stats. Identities = 26/141 (18%), Positives = 51/141 (36%), Gaps = 15/141 (10%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 G +V+VTG + + +V + G +V + S L++ Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKY--------PG 61 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL- 126 +T V E + + G D V+ A S + + +++ + GT + A Sbjct: 62 RFETAVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNK-YDEVVTPAIGGTLNALRAAAA 120 Query: 127 -PYLRKSQGNVINISSLVGAI 146 P ++ + SS V A+ Sbjct: 121 TPSVK----RFVLTSSTVSAL 137 >2Z95-A nrPDB Length = 345 Score = 34.1 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 37/100 (37%), Gaps = 11/100 (11%) Query: 7 YAGKVVVVTGGGRGI-GAGIVRAFVNSGARVVICDKDE---SGGRALEQELPGAV-FILC 61 +GK ++TG RG GA + + + G V D+ + R E + V I Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHM 59 Query: 62 DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEE 101 D+ + ++ + + D V N A E+ Sbjct: 60 DLLEFSNIIRTIEKVQ-----PDEVYNLAAQSFVGVSFEQ 94 >4WPG-A nrPDB Length = 289 Score = 34.1 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 43/137 (31%), Gaps = 30/137 (21%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 +++TG +G + G V D E D+T ED V+ Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVDVAE-----------------MDITNEDKVEA 49 Query: 72 LVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK 131 + ++ V + A + +E A +N+ G+ + K Y Sbjct: 50 VFAQVKPTL-----VYHCAAYTAVDAAEDEGKALN----EAINVTGSENIAKACGKY--- 97 Query: 132 SQGNVINISSLVGAIGQ 148 ++ IS+ G Sbjct: 98 -GATLVYISTDYVFDGN 113 >5ENV-A nrPDB Length = 347 Score = 34.1 bits (77), Expect = 0.070, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 54/150 (36%), Gaps = 15/150 (10%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNS-GARVVICDKDESGGRALEQELPGAVFI 59 + + AG V ++G G+G + + + G RV+ D E G L + + G VFI Sbjct: 162 LKSANLMAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGIDGGE-GKEELFRSIGGEVFI 219 Query: 60 LCDVTQEDDVKTLVSETIR--RFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLG 117 D T+E D+ V + G ++ V+ A + L+G Sbjct: 220 --DFTKEKDIVGAVLKATDGGAHGVINVSVSEAAIEASTRYVRANG--------TTVLVG 269 Query: 118 TYTLTKLALPYLRKSQGNVINISSLVGAIG 147 K + ++ + S VG Sbjct: 270 MPAGAKCCSDVFNQVVKSISIVGSYVGNRA 299 >6DEB-A nrPDB Length = 285 Score = 34.1 bits (77), Expect = 0.072, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 16/35 (45%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK 41 GK V+ G +G + +N+GA V +C Sbjct: 158 LEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHI 192 >2HK7-A nrPDB Length = 269 Score = 34.1 bits (77), Expect = 0.073, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 K ++V G G G ++ A V GA+V + ++ + L Q+ P V V ++V Sbjct: 124 KSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEV-----VNSPEEV 177 Query: 70 KTLVSETIRR 79 V + Sbjct: 178 IDKVQVIVNT 187 >3VPX-A nrPDB Length = 364 Score = 34.1 bits (77), Expect = 0.075, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 19/49 (38%), Gaps = 1/49 (2%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG 55 AGK V V G G + + GA+++I D +E + Sbjct: 171 LAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGA 218 >4BKP-A nrPDB Length = 336 Score = 33.7 bits (76), Expect = 0.084, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 38/118 (32%), Gaps = 21/118 (17%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 + ++VTGG +G I +VV G + A D+T Sbjct: 20 FQSMRILVTGGSGLVGKAI--------QKVVADGAGLPGEDWVFVSSKDA-----DLTDT 66 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELN---LLGTYTL 121 + L + V++ A R + + +R+ + +N L + + Sbjct: 67 AQTRALFEKVQPTH-----VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 119 >5JXW-A nrPDB Length = 498 Score = 33.7 bits (76), Expect = 0.091, Method: Composition-based stats. Identities = 33/175 (18%), Positives = 54/175 (30%), Gaps = 42/175 (24%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 AGK +VV G G +G G + GARV++ + D E + DV E Sbjct: 269 LAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLE-DVVSE 326 Query: 67 DDVKTLVSETIRRFGRLDCVVN--------NAGHHPPPQRPEETSAQGFR-----QLLEL 113 D+ I G D + NA +E G +++E+ Sbjct: 327 ADI------FITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYGLENYPGIKVIEV 380 Query: 114 --NL---------LGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVAT 157 N+ L K G ++N+ G ++ + Sbjct: 381 KQNVHKFTFPDTQKSVILLCK----------GRLVNLGCATGHPPLVMSMSFTNQ 425 >3BIC-A nrPDB Length = 762 Score = 33.7 bits (76), Expect = 0.096, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 13/107 (12%) Query: 16 GGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSE 75 G RG I F + G V I ++ +Q + V + T KTLV E Sbjct: 616 GHDRG-AKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPE 674 Query: 76 TIRRF---GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 I+ GR D +V G PP Q + L E+ + + Sbjct: 675 LIKELNSLGRPDILVMCGGVIPP---------QDYEFLFEVGVSNVF 712 >2Q4B-A nrPDB Length = 253 Score = 33.3 bits (75), Expect = 0.100, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 26/77 (33%), Gaps = 8/77 (10%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 V+VTG G IV + G+ + + E+ A + D+T D + Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGSDKFVAKGLVRSAQGKEKIGGEADVFIGDITDADSIN 64 Query: 71 TLVSETIRRFGRLDCVV 87 +D +V Sbjct: 65 PAFQ-------GIDALV 74 >4EUF-A nrPDB Length = 418 Score = 33.3 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 31/96 (32%), Gaps = 18/96 (18%) Query: 10 KVVVVTGGGRGIGAG--IVRAFVNSGARVV-ICDKDESGGRALE----------QELPGA 56 K V++ G G G I AF A + + + + R + +E Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 57 VFILC-----DVTQEDDVKTLVSETIRRFGRLDCVV 87 ++ D + ++ FG++D V Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >3PEF-A nrPDB Length = 287 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 42/253 (16%), Positives = 77/253 (30%), Gaps = 47/253 (18%) Query: 21 IGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDV-----------TQEDDV 69 +G+ + + V +G V I ++ L C+V Sbjct: 12 MGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAMLADPAAA 71 Query: 70 KTLV-------SETIRRFGRLD-------------CVVNNAGHHPPPQRPEETSAQGFRQ 109 + + G +D V G + Sbjct: 72 EEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVVAKGGRFLEAPVSGSKKPAEDG 131 Query: 110 LLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALA 169 L + G L A+P K +I++ VG + + V + G + + LA Sbjct: 132 TLIILAAGDRNLYDEAMPGFEKMGKKIIHLG-DVGKGAEMKLVVNMVMGGMMACFCEGLA 190 Query: 170 L----DESPYGVRVNCISPGNIWTPLWEELAALMPDP--------RATIREGMLAQPLG- 216 L + + ++ I G + P++ L+ D + ++ LA LG Sbjct: 191 LGEKAGLATDAI-LDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDLRLAVALGD 249 Query: 217 RMGQPAEVGAAAV 229 R+GQP V +AA Sbjct: 250 RVGQPL-VASAAA 261 >4J6F-A nrPDB Length = 382 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 35/113 (30%), Gaps = 19/113 (16%) Query: 1 MATGTRYA-GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI 59 M R A G+ V+VTG G+G+ I + G + PG Sbjct: 198 MLERARLAAGETVLVTGASGGVGSAI-IQLARA-----------RGAVPIAVAGPGKEAA 245 Query: 60 LCDVTQEDDVKT----LVSETIRRFGR--LDCVVNNAGHHPPPQRPEETSAQG 106 + D+ + V L G +D V + G + +G Sbjct: 246 MLDIGAQAVVTRGQGDLAEAVEAASGGRPIDVVADLVGGPLFNDLLKILRPEG 298 >6GBN-A nrPDB Length = 438 Score = 32.9 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD 42 AT AGKV VV G G +G G + +GARV++ + D Sbjct: 212 ATDVMMAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEID 251 >4EJ0-A nrPDB Length = 342 Score = 32.9 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 49/160 (30%), Gaps = 28/160 (17%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK 70 ++VTG IGA +V+A G +I + + + + C++ D Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKN------LVDCEIDDYLDKT 67 Query: 71 TLVSE-TIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYL 129 V FG++ V + +T R +++ N + ++ L Sbjct: 68 EFVERFARGDFGKVRAVFH-------EGACSDTMETDGRYMMDNN----FRYSRAVLDAC 116 Query: 130 RKSQGNVINISSLVGAIGQ----------AQAVPYVATKG 159 + SS G A Y +K Sbjct: 117 LAQGAQFLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >3DMF-A nrPDB Length = 381 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 34/96 (35%), Gaps = 9/96 (9%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 G+ V+ G G G + GA VV + D + +L++ L + + Sbjct: 232 VRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLE------ANALKA 282 Query: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEET 102 + + V E + R D +V N H + Sbjct: 283 QALHSDVDEALTEEARFDIIVTNPPFHVGGAVILDV 318 >4J90-A nrPDB Length = 222 Score = 32.9 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R K V G GR G I + G V+ D +E A ++ + T+ Sbjct: 3 RIKNKQFAVIGLGR-FGGSICKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATE 59 Query: 66 EDDVKTL 72 E+++ +L Sbjct: 60 ENELLSL 66 >4MIT-A nrPDB Length = 186 Score = 32.9 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 24/56 (42%), Gaps = 4/56 (7%) Query: 24 GIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRR 79 IV+ G V+ + + G L+ + +I C +++KT+ E ++ Sbjct: 131 AIVKRLTEQGMTVI----NTAKGEELKNRIKAVKYIECSAKTSENLKTVFDEAVKT 182 >4WOK-A nrPDB Length = 336 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 50/142 (35%), Gaps = 17/142 (11%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 V+V GG IG+ + G V+ D +G ++ + F+ D+ + Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGD---FVEGDILD----QA 66 Query: 72 LVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK 131 + ET+ ++ + A H S + + N+ G T+ L R Sbjct: 67 RLVETMEKYAPV------AVIHFAASAYVGESVEDPAKYYRNNVGG----TQSLLDACRL 116 Query: 132 SQGNVINISSLVGAIGQAQAVP 153 ++ + SS G +P Sbjct: 117 TRTQNVIFSSSCATYGVPSRLP 138 >5GUP-L nrPDB Length = 377 Score = 32.5 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 57/162 (35%), Gaps = 28/162 (17%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR---ALEQELPGAVFI 59 + +G V V G +G +V G++V++ + E +L +F+ Sbjct: 47 GRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFM 106 Query: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 + +D ++ +V + + V+N G ET F + + Sbjct: 107 EWNGKDKDSIRKVVEHS-------NVVINLVGREW------ETKNFDFEDV--------F 145 Query: 120 TLTKLALPYLRKSQG--NVINISSLVGAIGQAQAVPYVATKG 159 A+ + K G +I+IS L I Y+ +K Sbjct: 146 VKIPHAIAQVSKEAGVEKLIHISHLNADIKSPSR--YLRSKA 185 >6C6P-A nrPDB Length = 458 Score = 32.1 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL--PGAVFILCDVTQEDDV 69 V++ G G +G+ + G +V + ++D + E PG +L D+ D V Sbjct: 10 VIIVGAGV-LGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLGDTV 68 Query: 70 KTLVSETIR 78 + L ++ + Sbjct: 69 EGLDAQVVN 77 >4KUG-A nrPDB Length = 290 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDES 44 K V V G G +GAGIV+AF G V++ D E Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEE 35 >3IP1-A nrPDB Length = 404 Score = 31.8 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDD 68 G VV+ GGG IG V ++GA VI + R L +EL I D T+E+ Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVI--DPTKENF 270 Query: 69 VKTLVS 74 V+ ++ Sbjct: 271 VEAVLD 276 >1MLD-A nrPDB Length = 314 Score = 31.8 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 36/134 (26%), Gaps = 23/134 (17%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 KV V G GIG + N R ++ + D++ + Sbjct: 2 KVA-VLGASGGIGQPLSLLLKN----------SPLVSRLTLYDIAHTPGVAADLSHIETR 50 Query: 70 KTLV-----SETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 T+ + D VV AG P L N TLT Sbjct: 51 ATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR-------DDLFNTNATIVATLTAA 103 Query: 125 ALPYLRKSQGNVIN 138 + + +I+ Sbjct: 104 CAQHCPDAMICIIS 117 >1ZDL-A nrPDB Length = 517 Score = 31.8 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 1/43 (2%) Query: 13 VVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG 55 +V GGG G G + G +V + D E R + L G Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGG 77 >2VN8-A nrPDB Length = 375 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 31/87 (35%), Gaps = 9/87 (10%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 GK V++ G G+G ++ A V ++ L ++L DV Sbjct: 183 TGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDAS--ELVRKLGAD-----DVIDYK 235 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHP 94 V E ++ D +++N G Sbjct: 236 S--GSVEEQLKSLKPFDFILDNVGGST 260 >4B4O-A nrPDB Length = 298 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 20/53 (37%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVT 64 V+V GG IG + + G V + + GR EL + CD Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAA 55 >5BUT-A nrPDB Length = 288 Score = 31.8 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R K V G GR G IV+ G V+ D +E A ++ + T+ Sbjct: 3 RIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATE 59 Query: 66 EDDVKTL 72 E+++ +L Sbjct: 60 ENELLSL 66 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 5/56 (8%) Query: 20 GIGA---GIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTL 72 G+G IV+ G V+ D +E A ++ + T+E+++ +L Sbjct: 155 GLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELLSL 208 >2HMT-A nrPDB Length = 144 Score = 31.8 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 R K V G GR G IV+ G V+ D +E A ++ + T+ Sbjct: 3 RIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATE 59 Query: 66 EDDVKTL 72 E+++ +L Sbjct: 60 ENELLSL 66 >1E3J-A nrPDB Length = 352 Score = 31.8 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 30/75 (40%), Gaps = 3/75 (4%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDD 68 G V+V G G IG V A GA VV + + + V ++ D +E++ Sbjct: 169 GTTVLVIGAGP-IGLVSVLAAKAYGAFVVCTARSPRRL-EVAKNCGADVTLVVDPAKEEE 226 Query: 69 VKTLVSETIRRFGRL 83 +++ G L Sbjct: 227 -SSIIERIRSAIGDL 240 >3D64-A nrPDB Length = 494 Score = 31.4 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 38/115 (33%), Gaps = 7/115 (6%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVF--I 59 AT AGK+ VV G G +G G ++ GA V + + D E V Sbjct: 270 ATDVMIAGKIAVVAGYGD-VGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEY 328 Query: 60 LCDVTQ----EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQL 110 D +++ + R + +V N GH T + + Sbjct: 329 AADKADIFVTATGNYHVINHDHMKAMRHNAIVCNIGHFDSEIDVASTRQYQWENI 383 >1Z1W-A nrPDB Length = 780 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 33/222 (14%), Positives = 58/222 (26%), Gaps = 45/222 (20%) Query: 42 DESGGRALEQELPGAVFILCDVTQEDDVKTLVSET-----------IRRFGRL------- 83 + G L I DV D++ + E I + Sbjct: 315 SRTSGALRSDSLKNTHPIEVDVRDPDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGI 374 Query: 84 -----DCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLR-KSQGNVI 137 D NA E+ S + ++++E Y + P ++ K G I Sbjct: 375 SKYLNDHKFGNAEGSDLWTAIEDVSGKPVKRVME------YWIKNPGYPVIKLKRNGRKI 428 Query: 138 NISSL-----VGAIGQAQAVPYVATKGAVTAMTKALALDESPYG-VRVNCISPGNIWTPL 191 + G+ + K V + G +++N S G Sbjct: 429 TMYQTRFLLNGEEEGRWPVPVNIKKKDGVERILLEDEASIEADGLIKINADSAGF----- 483 Query: 192 WEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS 233 + + PL R+G + FL S Sbjct: 484 -YRVLYDDATFSDVMGHYRDLSPLDRIGLVDD---LFAFLLS 521 >4WLE-A nrPDB Length = 340 Score = 31.4 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 31/124 (25%), Gaps = 23/124 (18%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 KV V G GIG + N R ++ + D++ + Sbjct: 28 KVA-VLGASGGIGQPLSLLLKN----------SPLVSRLTLYDIAHTPGVAADLSHIETK 76 Query: 70 KTLV-----SETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKL 124 + + D VV AG P L N TLT Sbjct: 77 AAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR-------DDLFNTNATIVATLTAA 129 Query: 125 ALPY 128 + Sbjct: 130 CAQH 133 >3PVZ-A nrPDB Length = 399 Score = 31.4 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 26/226 (11%), Positives = 65/226 (28%), Gaps = 28/226 (12%) Query: 13 VVTGGGRGIGAGIVRA-FVNSGARVVICDKDESGGRALEQELPGAVFI--------LCDV 63 +V GG IG + + F + ++ + D E+ L +++ + D+ Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFALDI 98 Query: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 + I+ G+ D V+N E +++++N+ T + Sbjct: 99 GSIE-----YDAFIKADGQYDYVLN---LSALKHVRSEKDPFTLMRMIDVNVFNTDKTIQ 150 Query: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183 ++ K + A+K + + + + R ++ Sbjct: 151 QSIDAGAKKYFC------VSTDKAANPVNMMGASKRIMEMFLMRKSEEIAISTARFANVA 204 Query: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAV 229 L + + + + P E G + Sbjct: 205 --FSDGSLLHGFNQRIQKNQPIVAPNDIK---RYFVTPQESGELCL 245 >1EDZ-A nrPDB Length = 320 Score = 31.0 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 22/66 (33%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCD 62 G R GK +V +G + N GA V D + + L + D Sbjct: 171 EGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVED 230 Query: 63 VTQEDD 68 + + + Sbjct: 231 LGEYSE 236 >6BI4-A nrPDB Length = 346 Score = 31.0 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 27/169 (15%), Positives = 63/169 (37%), Gaps = 25/169 (14%) Query: 12 VVVTGGGRGIGAGIVRAFVN--SGARVV----ICDKDESGGRALEQELPGAVFILCDVTQ 65 ++VTGG IG+ V + +++ + Q+ P F+ ++ Sbjct: 27 ILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGEIQN 86 Query: 66 EDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125 + ++ ++ E + +VN A + + S + + N++GT TL +L Sbjct: 87 GELLEHVIKERDVQ-----VIVNFAA-----ESHVDRSIENPIPFYDTNVIGTVTLLELV 136 Query: 126 --LPYLR-------KSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMT 165 P+++ + G++ A PY ++K + + Sbjct: 137 KKYPHIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKASADMIA 185 >1IE3-A nrPDB Length = 312 Score = 31.0 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 34/130 (26%), Gaps = 14/130 (10%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 KV V G GIG + + E + PG L + + Sbjct: 2 KVA-VLGAAGGIGQALALLLKTQ-----LPSGSELSLYDIAPVTPGVAVDLSHIPTAVKI 55 Query: 70 KTL-VSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPY 128 K + D V+ +AG P L +N L + Sbjct: 56 KGFSGEDATPALEGADVVLISAGVARKPGMDRS-------DLFNVNAGIVKNLVQQVAKT 108 Query: 129 LRKSQGNVIN 138 K+ +I Sbjct: 109 CPKACIGIIT 118 >2EER-A nrPDB Length = 347 Score = 31.0 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 36/107 (33%), Gaps = 30/107 (28%) Query: 9 GKVVVVTGGGRGIGA-GIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 K +VV G G G+G I A SGA ++ D E A ++ Sbjct: 171 SKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRA--------------- 215 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELN 114 D V+N + P + T +G +++LN Sbjct: 216 --------------GADYVINASSQDPVSEIRRITQGKGADAVIDLN 248 >2OWO-A nrPDB Length = 671 Score = 31.0 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 5/72 (6%) Query: 7 YAGKVVVVTGGGRGIGAGIVR-AFVNSGARVVICDKDES----GGRALEQELPGAVFILC 61 +AGK VV+TG + + V GA+V ++ G A +L A + Sbjct: 598 FAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGI 657 Query: 62 DVTQEDDVKTLV 73 +V E ++ L+ Sbjct: 658 EVIDEAEMLRLL 669 >6ACQ-A nrPDB Length = 302 Score = 30.6 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDES 44 K V V G G +G+GI +AF G VV+ D + Sbjct: 22 KKVCVIGAGT-MGSGIAQAFAAKGFEVVLRDIKDE 55 >4N7R-A nrPDB Length = 472 Score = 30.6 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 26/47 (55%), Gaps = 2/47 (4%) Query: 14 VTGGGRGIGAGIVRAFVNSGA-RVVICDKDESGGRALEQELPGAVFI 59 V G G+ +G +++ + G +VV+ ++ E A+ +E+PG I Sbjct: 212 VIGAGK-MGKLVIKHLMAKGCTKVVVVNRSEERVSAIREEMPGIEII 257 >2DFV-A nrPDB Length = 347 Score = 30.6 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 15/79 (18%) Query: 8 AGKVVVVTGGG--RGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFI------ 59 +GK V++TG G +G + +A SGA VI + R L +++ I Sbjct: 166 SGKSVLITGAGPLGLLGIAVAKA---SGAYPVIVSEPSDFRRELAKKVGADYVINPFEED 222 Query: 60 ----LCDVTQEDDVKTLVS 74 + D+T + V + Sbjct: 223 VVKEVMDITDGNGVDVFLE 241 >3S2F-A nrPDB Length = 340 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 18/52 (34%), Gaps = 3/52 (5%) Query: 25 IVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSET 76 + R GA V + +D L++E+ GA +L + Sbjct: 205 LARRL---GAEVAVNARDTDPAAWLQKEIGGAHGVLVTAVSPKAFSQAIGMV 253 >4B4V-A nrPDB Length = 303 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 10/90 (11%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 AGK VV G +G + + + A V IC L ++ A I+ V + + Sbjct: 178 AGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQ---ADIIVGAVGKAE 234 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQ 97 ++ + + + VV +AG HP Sbjct: 235 LIQ-------KDWIKQGAVVVDAGFHPRDG 257 >1JAY-A nrPDB Length = 212 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD 42 +V ++ GG +G G+ G +V+ + Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRR 33 >4A5O-A nrPDB Length = 286 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 15/40 (37%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK 41 +TG G VV G +G + + G V + + Sbjct: 154 STGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHR 193 >3COS-A nrPDB Length = 381 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 37/94 (39%), Gaps = 9/94 (9%) Query: 17 GGRGIGAGIVRAFVNSGA-RVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSE 75 G G+G V +GA R++ D + + ++ + GA D D+ + E Sbjct: 206 GLGGVGLSAVMGCKAAGASRIIGIDINSE--KFVKAKALGAT----DCLNPRDLHKPIQE 259 Query: 76 TIRRF--GRLDCVVNNAGHHPPPQRPEETSAQGF 107 I G +D ++ AG + + + G+ Sbjct: 260 VIIELTKGGVDFALDCAGGSETMKAALDCTTAGW 293 >3ZU2-A nrPDB Length = 422 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 42/132 (31%), Gaps = 27/132 (20%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARV----VICDKDESGGRA--------------LEQ 51 K V+V G G G R G V ++ G+ Q Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 52 ELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLL 111 + A I D ++ + + + G++D V+ + P+R + + F L Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLA---SPRRTHPKTGEVFNSAL 180 Query: 112 -----ELNLLGT 118 +NL G Sbjct: 181 KPIGNAVNLRGL 192 >3DC2-A nrPDB Length = 529 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 10/99 (10%) Query: 3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA---------LEQEL 53 +GT GK V V G GR IG + + GA VV D S RA L+ L Sbjct: 136 SGTEIFGKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLL 194 Query: 54 PGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGH 92 A FI + + + L+ + + ++ NA Sbjct: 195 ARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAAR 233 >2V6G-A nrPDB Length = 364 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 22/66 (33%), Gaps = 8/66 (12%) Query: 11 VVVVTGGGRGIGAGIVRAFVNSG-----ARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 V ++ G IG + + +V + R E ++ CD++ Sbjct: 3 VALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVAR---RTRPAWHEDNPINYVQCDISD 59 Query: 66 EDDVKT 71 DD + Sbjct: 60 PDDSQA 65 >2X86-A nrPDB Length = 357 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 34/81 (41%), Gaps = 8/81 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDV 69 ++++VTGG IG+ IV+A + G I D L+ + ++ D Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKG----ITDIL--VVDNLKDGTKFVNLVDLNIADYMDK 100 Query: 70 KTLVSE--TIRRFGRLDCVVN 88 + + + FG ++ + + Sbjct: 101 EDFLIQIMAGEEFGDVEAIFH 121 >1LLU-A nrPDB Length = 342 Score = 29.1 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 33/88 (37%), Gaps = 6/88 (6%) Query: 17 GGRGIGAG--IVRAFVNS-GARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLV 73 GIG + + + G V D D++ L ++L ++ + + QED V+ + Sbjct: 175 AISGIGGLGHVAVQYARAMGLHVAAIDIDDAKL-ELARKLGASLTV--NARQEDPVEAIQ 231 Query: 74 SETIRRFGRLDCVVNNAGHHPPPQRPEE 101 + G L V+N+ Sbjct: 232 RDIGGAHGVLVTAVSNSAFGQAIGMARR 259 >5AOV-A nrPDB Length = 336 Score = 29.1 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 20/54 (37%), Gaps = 3/54 (5%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV 57 G GK + + G GR IG I R G + I + E+EL Sbjct: 145 GYELYGKTIGIVGFGR-IGQAIARR--AKGFNMRILYYSRTRKSQAEKELGAEY 195 >6C55-A nrPDB Length = 340 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 25/67 (37%), Gaps = 1/67 (1%) Query: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66 GK + V G G G + ++G VVI + +++ + V Q Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQA 73 Query: 67 DDVKTLV 73 D + L+ Sbjct: 74 DVIMVLL 80 >3R9I-A nrPDB Length = 260 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 16/36 (44%), Gaps = 5/36 (13%) Query: 10 KVVVVTGGGRGIGA-----GIVRAFVNSGARVVICD 40 +++VVT G G+G I G + V+ D Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVID 38 >6BMQ-A nrPDB Length = 523 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 31 NSGARVVICDKDESGGRALEQELPGAVFILCDVTQ 65 GA+VVI ++ L + + G L D+ Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKALSLTDLDN 419 >2WEK-A nrPDB Length = 341 Score = 29.1 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 12/41 (29%), Gaps = 2/41 (4%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFV-NSGARVVICDKDESGGR 47 GK V+VT G G + V+ + Sbjct: 142 EGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEKSA 181 >1ZCJ-A nrPDB Length = 463 Score = 29.1 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 14/31 (45%) Query: 21 IGAGIVRAFVNSGARVVICDKDESGGRALEQ 51 +G GI +F G VV + D A ++ Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKK 78 >1JPH-A nrPDB Length = 388 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 29/76 (38%), Gaps = 8/76 (10%) Query: 27 RAFVNSGARVVICDKDESGGRALEQELPGAVFILCDV------TQEDDVKTLVSETIRRF 80 +G VV D + +A + + V + ++ E+++ LV + + F Sbjct: 291 EELAQAGYEVVGLDWTVAPKKA-RECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDF 349 Query: 81 GRLDCVVN-NAGHHPP 95 G + N G +P Sbjct: 350 GPHRYIANLGHGLYPD 365 >1V8B-A nrPDB Length = 479 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 58/168 (34%), Gaps = 25/168 (14%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED 67 +GK+VV+ G G +G G + GARV I + D E +V D Sbjct: 256 SGKIVVICGYGD-VGKGCASSMKGLGARVYITEIDPICAIQAVMEG-------FNVVTLD 307 Query: 68 DVKTLVSETIRRFGRLDC--------VVNNAGHHPPPQRPEETSAQ---GFRQLLELNLL 116 ++ I G +D + NNA +E ++ + N+ Sbjct: 308 EIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVNELFNYKGIHIENVK 367 Query: 117 GTYTLTKLALPYLRK----SQGNVINISSLVGAIGQAQAVPYVATKGA 160 + ++ LP K ++G ++N+ G + + A Sbjct: 368 --PQVDRITLPNGNKIIVLARGRLLNLGCATGHPAFVMSFSFCNQTFA 413 >3HDH-A nrPDB Length = 302 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV 57 K V V GGG +GAGI + +G VV+ D+ E ++ + ++ Sbjct: 16 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL 62 >4A10-A nrPDB Length = 447 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 37/98 (37%), Gaps = 14/98 (14%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSG----ARVVICDKDESGGRALEQEL---P 54 G +V++ G G+G FV +G VV + E+ RAL +L Sbjct: 214 RGAQMKQGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINR 272 Query: 55 GAVFILCDVTQE-----DDVKTLVSETIRRFGR-LDCV 86 + I D+ + + + L + + GR D V Sbjct: 273 AELGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIV 310 >1F14-A nrPDB Length = 310 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAV 57 K V V GGG +GAGI + +G VV+ D+ E ++ + ++ Sbjct: 16 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL 62 >7REQ-A nrPDB Length = 727 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 29/80 (36%), Gaps = 5/80 (6%) Query: 25 IVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQED----DVKTLVSETIRRF 80 I A+ + G V + ++ Q + V ++ V+ + + + + + Sbjct: 616 IATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVG-VSSLAGGHLTLVPALRKELDKL 674 Query: 81 GRLDCVVNNAGHHPPPQRPE 100 GR D ++ G P E Sbjct: 675 GRPDILITVGGVIPEQDFDE 694 >3FBG-A nrPDB Length = 346 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 9/51 (17%), Positives = 17/51 (33%), Gaps = 2/51 (3%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNS-GARVVICDKDESGGRALEQ 51 GK +++ G G+G I + G RV+ ++ Sbjct: 144 RNRNENEGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIEWTKK 193 >1EQ2-A nrPDB Length = 310 Score = 28.7 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 32/79 (40%), Gaps = 8/79 (10%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKT 71 ++VTGG IG+ IV+A + G I D L+ + ++ D + Sbjct: 2 IIVTGGAGFIGSNIVKALNDKG----ITDIL--VVDNLKDGTKFVNLVDLNIADYMDKED 55 Query: 72 LVSE--TIRRFGRLDCVVN 88 + + FG ++ + + Sbjct: 56 FLIQIMAGEEFGDVEAIFH 74 >3ZWA-A nrPDB Length = 742 Score = 28.7 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 14/31 (45%) Query: 21 IGAGIVRAFVNSGARVVICDKDESGGRALEQ 51 +G GI +F G VV + D A ++ Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKK 357 >1C0L-A nrPDB Length = 363 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 15/38 (39%), Gaps = 1/38 (2%) Query: 5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD 42 ++ K VVV G G IG G V I +D Sbjct: 2 MMHSQKRVVVLGSGV-IGLSSALILARKGYSVHILARD 38 >4N18-A nrPDB Length = 332 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 21/69 (30%), Gaps = 20/69 (28%) Query: 21 IGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRF 80 IG I G RV + E ++L G E + F Sbjct: 167 IGGYIADQLARLGYRVSGWSRSE-------KQLAGVTCYRG------------EEALDHF 207 Query: 81 -GRLDCVVN 88 G LD ++N Sbjct: 208 LGSLDGLIN 216 >1ZEJ-A nrPDB Length = 293 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 7/75 (9%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVT----Q 65 KV V+ G +G GI A + VV+ D E A +++P + + T + Sbjct: 14 KVFVI--GAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIPEELLSKIEFTTTLEK 70 Query: 66 EDDVKTLVSETIRRF 80 D ++ Sbjct: 71 VKDCDIVMEAVFEDL 85 >1DB3-A nrPDB Length = 372 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 24/78 (30%), Gaps = 9/78 (11%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL---------PGAVFI 59 KV ++TG G+ + + G V + S + P Sbjct: 1 SKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLH 60 Query: 60 LCDVTQEDDVKTLVSETI 77 D++ ++ ++ E Sbjct: 61 YGDLSDTSNLTRILREVQ 78 >3G1U-A nrPDB Length = 437 Score = 28.3 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 53/151 (35%), Gaps = 10/151 (6%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 AT AGK V G G +G G A GARVV+ + D E + Sbjct: 205 ATDVMIAGKTCCVCGYGD-VGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVALVE- 262 Query: 62 DVTQEDDVKTLVSE-----TIRRFGRL--DCVVNNAGHHPPPQRPEETSAQGFRQLLELN 114 DV + + + T F + D +V N GH + A ++ +E+ Sbjct: 263 DVMADAHIFVTTTGNDDIITSDHFPHMRDDAIVCNIGHFDTEIQVGWLEANA-KEHVEIK 321 Query: 115 LLGTYTLTKLALPYLRKSQGNVINISSLVGA 145 + + ++G ++N+ G Sbjct: 322 PQVDRYTMENGRHIILLAKGRLVNLGCASGH 352 >2Q1T-A nrPDB Length = 377 Score = 28.3 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPGAVFI 59 + ++ A V+V GG +G+ +V+ + G V + D S + + P F Sbjct: 24 IMNASKLANTNVMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLSAEKINVPDHPAVRFS 83 Query: 60 LCDVTQEDDVKTLVSE 75 +T + + +L E Sbjct: 84 ETSITDDALLASLQDE 99 >3L07-A nrPDB Length = 285 Score = 28.3 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 7/73 (9%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRA-------LEQELPGA 56 G + G VV G +G + + +N+ A V C + + ++ L + Sbjct: 156 GIKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKSHTTKADILIVAVGKP 215 Query: 57 VFILCDVTQEDDV 69 FI D+ +E V Sbjct: 216 NFITADMVKEGAV 228 >2ZJ1-A nrPDB Length = 495 Score = 28.3 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDD 68 GK V++ G G +G G A GARV + + D E V + + D Sbjct: 275 GKKVLICGYGD-VGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADI 333 Query: 69 VKTL 72 V T Sbjct: 334 VVTA 337 >3H0K-A nrPDB Length = 178 Score = 28.3 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%), Gaps = 2/30 (6%) Query: 10 KVVVVTGGGRGIGA-GIVRAFVNSGARVVI 38 KV+++TG G G + GA+V++ Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIV 29 >4EKJ-A nrPDB Length = 500 Score = 28.3 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 12/84 (14%) Query: 193 EELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAV---FLA------SEANFCTGIEL 243 + AA T R P R+G PA AA FLA S +F T Sbjct: 173 ADQAAYFELYDVTARAIKAIDPSLRVGGPA-TAGAAWVPEFLAHVKKSGSAVDFVTTHTY 231 Query: 244 LVTGGAELGYGCKASRSTPVDAPD 267 V GG G + ++ +P +PD Sbjct: 232 GVDGGFLDEKGVQDTKLSP--SPD 253 >6FK3-A nrPDB Length = 536 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 29/89 (32%), Gaps = 10/89 (11%) Query: 158 KGAVTAMTKALALDES--PYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPL 215 K A+ A + + S P +R G + L + L P + + P Sbjct: 60 KAALKA--REAFAEWSRTPAPIR------GQVLFNLVKILEREKPTLTRLMVREVGKTPK 111 Query: 216 GRMGQPAEVGAAAVFLASEANFCTGIELL 244 G E A+F ASE G + Sbjct: 112 EAAGDVQEAIDTALFFASEGRRLYGQTVP 140 >1U3W-A nrPDB Length = 374 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 33/86 (38%), Gaps = 16/86 (18%) Query: 10 KVVVVTGGG-------RGIGAGIVRAFVNSG-ARVVICDKDESGGRALEQELPGAVFILC 61 KV VT G G+G +V +G AR++ D ++ A +EL I Sbjct: 185 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKF-AKAKELGATECI-- 241 Query: 62 DVTQEDDVKTLVSETIRRF--GRLDC 85 D K + E ++ G +D Sbjct: 242 ---NPQDYKKPIQEVLKEMTDGGVDF 264 >4GBJ-A nrPDB Length = 297 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 27/74 (36%), Gaps = 12/74 (16%) Query: 21 IGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCD-----------VTQEDDV 69 +G I + +G +V+ ++ S L + V D + + V Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVFSVLADDAAV 75 Query: 70 KTLVS-ETIRRFGR 82 + L S E + + G+ Sbjct: 76 EELFSMELVEKLGK 89 >4UUP-A nrPDB Length = 341 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 30/102 (29%), Gaps = 20/102 (19%) Query: 12 VVVTGGGRGIGAGIVRAFVNS---GARVVICDKDE-----SGGRALEQELPGAVF-ILCD 62 V++TG IG + G R V+ E + EL F L Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 63 VTQEDDVKTLVSETIRRF-----------GRLDCVVNNAGHH 93 V DD + + F R D + NAG Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIF 108 >3K30-A nrPDB Length = 690 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE 52 V+V G G G RA G VV+ + G + QE Sbjct: 394 VLVVGAGPS-GLEAARALGVRGYDVVLAEAGRDLGGRVTQE 433 >2AXQ-A nrPDB Length = 467 Score = 27.9 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Query: 6 RYAGKVVVVTGGGRGIGAGIVRAFVN-SGARVVICDKDESGGRALEQELPGAVFILCDVT 64 R+ GK V++ G + ++ V + + + +AL + G+ I DVT Sbjct: 20 RHMGKNVLLLG-SGFVAQPVIDTLAANDDINVTVACRTLANAQALAK-PSGSKAISLDVT 77 Query: 65 QEDDVKTLVSE 75 + + ++++ Sbjct: 78 DDSALDKVLAD 88 >5U9C-A nrPDB Length = 292 Score = 27.5 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 23/54 (42%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDV 63 + +++TGG +GA + A ++ V++ +++ E DV Sbjct: 6 RKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDV 59 >4AF0-B nrPDB Length = 556 Score = 27.5 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 20/59 (33%), Gaps = 7/59 (11%) Query: 27 RAFVNSGARVVICDKDE-------SGGRALEQELPGAVFILCDVTQEDDVKTLVSETIR 78 + +G VV+ D + + ++Q P I +V + L++ Sbjct: 287 KLLAEAGLDVVVLDSSQGNSVYQIEFIKWIKQTYPKIDVIAGNVVTREQAAQLIAAGAD 345 >1NHQ-A nrPDB Length = 447 Score = 27.5 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 17/47 (36%), Gaps = 6/47 (12%) Query: 4 GTRYAGKVV------VVTGGGRGIGAGIVRAFVNSGARVVICDKDES 44 + K V VV G IG AF +G +V + D + Sbjct: 137 AIKLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDR 183 >3K96-A nrPDB Length = 356 Score = 27.5 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 8/71 (11%), Positives = 21/71 (29%), Gaps = 1/71 (1%) Query: 17 GGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSET 76 G G + G +V + + ++ E ++ + + +K Sbjct: 36 GAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNNRYLP-NYPFPETLKAYCDLK 94 Query: 77 IRRFGRLDCVV 87 G D ++ Sbjct: 95 ASLEGVTDILI 105 >4E0B-A nrPDB Length = 313 Score = 27.5 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 17/37 (45%), Gaps = 4/37 (10%) Query: 8 AGKVVVVTGGGRGIGAGIVRAFVN---SGARVVICDK 41 A KV V+ G GIG + N +G+ + + D Sbjct: 3 AMKVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDI 38 >2MKI-A nrPDB Length = 203 Score = 27.5 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 18/48 (37%) Query: 65 QEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLE 112 E V+ L+ I G+L V++ P + + +++ Sbjct: 65 DESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD 112 >4W5U-B nrPDB Length = 408 Score = 27.5 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 30/85 (35%), Gaps = 10/85 (11%) Query: 52 ELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHH--PPPQRPEETSAQ---- 105 E P A + CD + D + L++ FG D +V A P + E T Sbjct: 183 EYPNACGLTCDSSGPDAFRNLMAALRSTFG--DELVTAAVTADGTPGGKIEATDYAGAAQ 240 Query: 106 --GFRQLLELNLLGTYTLTKLALPY 128 + ++ + G + P+ Sbjct: 241 YVDWYNVMTYDFFGAWDAQGPTAPH 265 >3K4W-A nrPDB Length = 291 Score = 27.5 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 30/74 (40%), Gaps = 15/74 (20%) Query: 140 SSLVGAIGQAQAVPYVATKG---------AVTAMTKALAL----DESPYGVRVNCISPGN 186 SS++G++ A K ++ A T+ A+ + G+R+ + PG Sbjct: 71 SSVLGSVSNADVAA--VAKAYPDKFHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGV 128 Query: 187 IWTPLWEELAALMP 200 TP+ + L P Sbjct: 129 WATPMHVDDRRLYP 142 >5TC4-A nrPDB Length = 316 Score = 27.5 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 14/34 (41%) Query: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGAR 35 TG GK VVV G + +G I GA Sbjct: 152 RTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAH 185 >4XRR-A nrPDB Length = 456 Score = 27.5 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 24/94 (25%), Gaps = 3/94 (3%) Query: 13 VVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--AVFILCDVTQEDDVK 70 VV G +G + GA VV D D L + V Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAATG 77 Query: 71 TLVSET-IRRFGRLDCVVNNAGHHPPPQRPEETS 103 L + T G D V+ G T Sbjct: 78 RLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTD 111 >3DOJ-A nrPDB Length = 310 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 13/97 (13%), Positives = 32/97 (32%), Gaps = 5/97 (5%) Query: 21 IGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRF 80 +G + + +G +V + ++ S L + +V ++ K ++ Sbjct: 32 MGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK--CKYTIAMLSDPC 89 Query: 81 GRLDCVVNNAGHHPPP---QRPEETSAQGFRQLLELN 114 L V + G + + S L++N Sbjct: 90 AALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKIN 126 >2BTW-A nrPDB Length = 254 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 76 TIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLL--GTYTLTKLALPYLRKSQ 133 T+ GR ++ + G +T+ + FR+ + NL G + + + + + Sbjct: 135 TLDELGR---LIASYGVKVKVNHASDTNIEDFRKQVAENLKQDGNFVIVNYLRKEIGQER 191 Query: 134 GNVIN 138 G I+ Sbjct: 192 GGHIS 196 >6AZ1-E nrPDB Length = 273 Score = 27.1 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 8 AGKVVVVT-GGGRG-IGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDV 63 GK V+VT G RG IG IV+ + GA I ++ G I D+ Sbjct: 174 QGKAVIVTGGANRGRIG-EIVKVECHPGA-FNIAHLKDASGAEFATRAANIFVIGKDL 229 >5ZQZ-B nrPDB Length = 474 Score = 27.1 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 18/61 (29%), Gaps = 1/61 (1%) Query: 170 LDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAV 229 + +R N + + TP + + L L R P EV + Sbjct: 44 KTLAKPNIR-NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 102 Query: 230 F 230 F Sbjct: 103 F 103 >3RI6-A nrPDB Length = 430 Score = 27.1 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 25/77 (32%), Gaps = 11/77 (14%) Query: 15 TGGGR--GIGAGIV------RAFVNSGARVVICDKDESGGRALEQELP---GAVFILCDV 63 TG +G+G+ +G VV D+ +L Q+ G DV Sbjct: 95 TGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFVDV 154 Query: 64 TQEDDVKTLVSETIRRF 80 V+ ET + Sbjct: 155 MDSLAVEHACDETTKLL 171 >4PZE-A nrPDB Length = 284 Score = 27.1 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 67/189 (35%), Gaps = 15/189 (7%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR---ALEQELPGAVFILCDVTQE 66 + V + G G +G GI +A G VV+ D ++ + A + +T+ Sbjct: 4 RTVGIVGAGT-MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 67 DDVKTLVS----ETIRRFGRLDCVVNNA--GHHPPPQRPEETSAQGFRQLLELNLLGTYT 120 D L + D V+ A + + ++ ++ + + + Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSIS 122 Query: 121 LTKLALPYLRKSQGNVINIS--SLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 +TKLA + I + + V + + + + T A +AL+ Y + Sbjct: 123 ITKLAA--VTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGKYPIT 180 Query: 179 VNCISPGNI 187 V SPG + Sbjct: 181 VKN-SPGFV 188 >2QTV-A nrPDB Length = 772 Score = 27.1 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 184 PGNIWTPLWEELAALMPDPRATIREGML-AQPLGRMGQPAEVGAAAVFLAS 233 G P + + AL+ +P+ E ++ PL R G+ A FL S Sbjct: 680 AGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLS 730 >5GXF-A nrPDB Length = 330 Score = 26.8 bits (58), Expect = 9.3, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 12/36 (33%) Query: 12 VVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGR 47 V+VTG G+G+ + G V Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >6IHE-A nrPDB Length = 303 Score = 26.8 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 38/104 (36%), Gaps = 9/104 (8%) Query: 10 KVVVVTGGGRGIGAGIVRAFVNSGA--RVVICDKDESGGRALEQELPGAVFILCDVTQED 67 KV + G G+ IG I + + SGA VI D E EL A T+ Sbjct: 2 KVGFI-GAGK-IGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFA-----TKGI 54 Query: 68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLL 111 L + ++ +D VV +AG P +++ Sbjct: 55 KANVLGTNSLDDVSGMDIVVISAGKPRKPGMSRRDLFVDNAKIM 98 >4A26-A nrPDB Length = 300 Score = 26.8 bits (58), Expect = 9.8, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 20/58 (34%) Query: 4 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILC 61 G AGK VV G +GA + + A V I S ++ + I Sbjct: 160 GIEMAGKRAVVLGRSNIVGAPVAALLMKENATVTIVHSGTSTEDMIDYLRTADIVIAA 217 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.318 0.153 0.442 Lambda K H 0.267 0.0468 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,151,346 Number of Sequences: 36641 Number of extensions: 525459 Number of successful extensions: 3718 Number of sequences better than 10.0: 417 Number of HSP's better than 10.0 without gapping: 410 Number of HSP's successfully gapped in prelim test: 201 Number of HSP's that attempted gapping in prelim test: 2100 Number of HSP's gapped (non-prelim): 658 length of query: 270 length of database: 10,336,785 effective HSP length: 95 effective length of query: 175 effective length of database: 6,855,890 effective search space: 1199780750 effective search space used: 1199780750 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.1 bits)