BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q99JR6 (245 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5Z9R-A nrPDB 512 e-146 1NUQ-A nrPDB 420 e-118 1GZU-A nrPDB 253 8e-68 1K4M-A nrPDB 54 4e-08 2H29-A nrPDB 48 4e-06 1KAM-A nrPDB 48 4e-06 1YUM-A nrPDB 45 2e-05 4YMI-A nrPDB 40 9e-04 4WSO-A nrPDB 39 0.001 3DV2-A nrPDB 32 0.18 3L93-A nrPDB 31 0.53 4PZ0-A nrPDB 30 0.70 1R9X-A nrPDB 30 1.2 3NV7-A nrPDB 30 1.2 6CBN-A nrPDB 29 2.3 6AYH-A nrPDB 28 2.6 5JBN-A nrPDB 28 3.2 5Z9Y-A nrPDB 28 3.5 6AH3-E nrPDB 27 7.5 >5Z9R-A nrPDB Length = 281 Score = 512 bits (1318), Expect = e-146, Method: Compositional matrix adjust. Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA 60 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA Sbjct: 37 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA 96 Query: 61 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP 120 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP Sbjct: 97 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP 156 Query: 121 SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPI 180 SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPI Sbjct: 157 SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPI 216 Query: 181 LQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG 240 LQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG Sbjct: 217 LQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG 276 Query: 241 KGKTG 245 KGKTG Sbjct: 277 KGKTG 281 >1NUQ-A nrPDB Length = 252 Score = 420 bits (1080), Expect = e-118, Method: Compositional matrix adjust. Identities = 199/242 (82%), Positives = 217/242 (89%), Gaps = 1/242 (0%) Query: 1 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA 60 MK+RIPVVLLACGSFNPITNMHLR+FEVARDHLHQTG YQVI+GIISPVND+YGKKDL A Sbjct: 1 MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDLAA 60 Query: 61 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP 120 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHH +LLRS QM+GPD K Sbjct: 61 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKAL 120 Query: 121 -SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSP 179 S AA+PELKLLCGADVLKTFQTPNLWKD HIQEIVEKFGLVCV R HDP+ YI++SP Sbjct: 121 FSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVSHDPKGYIAESP 180 Query: 180 ILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWK 239 IL+ QHNIHLA+EPV NEISATY+R+ALGQGQSVKYL+P+AVITYI+D GLY +WK Sbjct: 181 ILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWK 240 Query: 240 GK 241 GK Sbjct: 241 GK 242 >1GZU-A nrPDB Length = 290 Score = 253 bits (645), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 122/259 (47%), Positives = 175/259 (67%), Gaps = 20/259 (7%) Query: 4 RIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHH 63 + VVLLACGSFNPITNMHLRLFE+A+D+++ TGRY V++GIISPV D+Y KK L+ ++H Sbjct: 17 KTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGLIPAYH 76 Query: 64 RVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSA--QMDGP------- 114 RV MA LA + S W+ VD WES Q +W ET+KVLRHH +L S Q + P Sbjct: 77 RVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLEASDCDHQQNSPTLERPGR 136 Query: 115 --------DPSKTPS---ASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVC 163 D S+ S + A+P++KLLCGAD+L++F PNLWK I +IV +GL+C Sbjct: 137 KRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLLESFAVPNLWKSEDITQIVANYGLIC 196 Query: 164 VSRSGHDPERYISDSPILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVI 223 V+R+G+D +++I +S +L + + NIH+ E + N+IS+T +R+AL +GQS++YL+P+ V Sbjct: 197 VTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIANDISSTKIRRALRRGQSIRYLVPDLVQ 256 Query: 224 TYIRDQGLYINDGSWKGKG 242 YI LY ++ + G Sbjct: 257 EYIEKHNLYSSESEDRNAG 275 >1K4M-A nrPDB Length = 213 Score = 54.3 bits (129), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 68/239 (28%), Positives = 100/239 (41%), Gaps = 49/239 (20%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 L G+F+P+ HL+ E + + T R +I + P + + S R M Sbjct: 7 LFGGTFDPVHYGHLKPVETLANLIGLT-RVTIIPNNVPP----HRPQPEANSVQRKHMLE 61 Query: 70 LALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPEL 129 LA+ +D E ++ T + L+ +E GPD +P L Sbjct: 62 LAIADKPLFTLDERELKRNAPSYTAQTLKEWRQE--------QGPD----------VP-L 102 Query: 130 KLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQF----- 184 + G D L TF T W + + I++ L+ R G+ E P QQ+ Sbjct: 103 AFIIGQDSLLTFPT---WYE--YETILDNAHLIVCRRPGYPLEM---AQPQYQQWLEDHL 154 Query: 185 QHN-----------IHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 HN I+LA P N ISAT +R+ L G+S + LLPE V+TYI QGLY Sbjct: 155 THNPEDLHLQPAGKIYLAETPWFN-ISATIIRERLQNGESCEDLLPEPVLTYINQQGLY 212 >2H29-A nrPDB Length = 189 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 51/230 (22%) Query: 8 VLLACGSFNPITNMHLRLFEVARDHLH--QTGRYQVIEGIISPVNDSYGKKDLVASHHRV 65 ++L G FNPI H+ VA + H Q + + +SP+ + D + HR+ Sbjct: 4 IVLYGGQFNPIHTAHMI---VASEVFHELQPDEFYFLPSFMSPLKKHH---DFIDVQHRL 57 Query: 66 AMARL---ALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSA 122 M ++ L D + Q+ +T+K + H++ Sbjct: 58 TMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKD------------------- 98 Query: 123 SAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQ 182 EL + G D Q L K I+ + E V V+R + Sbjct: 99 ----SELYFVIGTD-----QYNQLEKWYQIEYLKEMVTFVVVNRDKNS------------ 137 Query: 183 QFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 Q N +A + +IS+T +R+ + +G+S++ L+P++V YI+ +GLY Sbjct: 138 QNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLY 187 >1KAM-A nrPDB Length = 194 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 54/225 (24%), Positives = 99/225 (44%), Gaps = 51/225 (22%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQV--IEGIISPVNDSYGKKDLVASHHRVAMARL 70 G+F+P N HL + A + L+Q G ++ + I P + +D S HRV M +L Sbjct: 14 GTFDPPHNGHLLM---ANEVLYQAGLDEIWFMPNQIPPHKQN---EDYTDSFHRVEMLKL 67 Query: 71 ALQTSDWIRVDPWESEQ---AQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALP 127 A+Q++ +++ E E+ + +TV +L+ + P+ Sbjct: 68 AIQSNPSFKLELVEMEREGPSYTFDTVSLLKQRY--------------PND--------- 104 Query: 128 ELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHN 187 +L + GAD+++ P +K + E++ + V R G E + P+L Sbjct: 105 QLFFIIGADMIEYL--PKWYK---LDELLNLIQFIGVKRPGFHVE---TPYPLL------ 150 Query: 188 IHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 A P E+S+T +R+ + YL+P+ V Y+ + GLY Sbjct: 151 --FADVPEF-EVSSTMIRERFKSKKPTDYLIPDKVKKYVEENGLY 192 >1YUM-A nrPDB Length = 242 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 43/235 (18%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISP-VNDSYGKKDLVASHHRVAMA 68 L G+F+P+ H+R + ++ + E + P + + V++ R+AM Sbjct: 27 LFGGTFDPVHIGHMR------SAVEMAEQFALDELRLLPNARPPHRETPQVSAAQRLAMV 80 Query: 69 RLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPE 128 A+ + + VDP E ++ + T+ L EL AA + Sbjct: 81 ERAVAGVERLTVDPRELQRDKPSYTIDTLESVRAEL-------------------AADDQ 121 Query: 129 LKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPE-----------RYISD 177 L +L G D T + W + +++ +V + R D E R ++D Sbjct: 122 LFMLIGWDAFCGLPTWHRW-----EALLDHCHIVVLQRPDADSEPPESLRDLLAARSVAD 176 Query: 178 SPILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 L+ I + L +SAT +R LG G+SV++L+P+AV+ YI LY Sbjct: 177 PQALKGPGGQITFVWQTPLA-VSATQIRALLGAGRSVRFLVPDAVLNYIEAHHLY 230 >4YMI-A nrPDB Length = 233 Score = 40.0 bits (92), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 55/231 (23%), Positives = 95/231 (41%), Gaps = 38/231 (16%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGK--KDLVASHHRVAMARL 70 G+F+PI N HL D R+ + E I P + K + + + HR M + Sbjct: 35 GTFDPIHNGHLVAASEVAD------RFALDEVIFVPTGQPWQKQGRKVSPAEHRYLMTVI 88 Query: 71 ALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPELK 130 A ++ V + ++ TV L LR++ PD +L Sbjct: 89 ATASNPRFTVSRADIDRGGATYTVDTLTD-----LRTAH----PDA-----------DLY 128 Query: 131 LLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHD-PERYISDSPILQQFQHNIH 189 + GAD L + + W++ + KF + VSR G++ +I+ + + + Sbjct: 129 FITGADALASILS---WENWEQLFTLAKF--IGVSRPGYELSSDHIAHAELPPD---GLS 180 Query: 190 LAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG 240 L P L IS+T R GQ + + YL+P+ V+ Y+ LY + +G Sbjct: 181 LVEVPAL-AISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYSGNKGNQG 230 >4WSO-A nrPDB Length = 271 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 49/163 (30%), Positives = 64/163 (39%), Gaps = 36/163 (22%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 G+F+PI + HL L D L T E ++ P Y K+D+ A+ HR+AM R A Sbjct: 57 GTFDPIHDGHLALARRFADVLRLT------ELVLMPAGQPYQKQDVSAAEHRLAMTRAAA 110 Query: 73 QT----SDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPE 128 + + V E E A TV+ L L G D S Sbjct: 111 GSLVLPGVAVSVATDEIEHAGPTYTVETLERWRERL--------GADAS----------- 151 Query: 129 LKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVC-VSRSGHD 170 L LL GAD L T W+D + F VC +R G D Sbjct: 152 LSLLIGADQLVRLDT---WRD---WRRLFDFAHVCAATRPGFD 188 >3DV2-A nrPDB Length = 201 Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%) Query: 199 ISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 +S++ +R+ + ++ KYLLPE V YI GLY Sbjct: 154 VSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLY 187 >3L93-A nrPDB Length = 162 Score = 30.8 bits (68), Expect = 0.53, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 9/57 (15%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 G+F+PITN HL L T + +I + DS KK + RVA+A+ Sbjct: 12 GTFDPITNGHLDLV---------TRASAMFSHVILAIADSSSKKPMFTLDERVALAK 59 >4PZ0-A nrPDB Length = 324 Score = 30.4 bits (67), Expect = 0.70, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 114 PDPSKTPSASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSG 168 PD + P+ + A LK+ V+ F TPN+ +D + V++FGL V + G Sbjct: 202 PDATALPAMAQAAENLKMDKKV-VVTGFSTPNVMRDYVKRGTVQQFGLWDVKQQG 255 >1R9X-A nrPDB Length = 430 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 16/152 (10%) Query: 53 YGKKDLVASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMD 112 YG + L H A+A+ + D + D + EQ++++ETV L HH R +A Sbjct: 196 YGVESL---HKTFALAQKYDRLID-VHCDEIDDEQSRFVETVAALAHHEGMGARVTASHT 251 Query: 113 GPDPSKTPSASAALPELKLLCGADVLKT----------FQT-PNLWKDTHIQEIVEKFGL 161 S + ++ L L + G + + F T P T ++E++E Sbjct: 252 TAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLESGIN 311 Query: 162 VCVSRSG-HDPERYISDSPILQQFQHNIHLAR 192 VC G DP + + +LQ +H+ + Sbjct: 312 VCFGHDGVFDPWYPLGTANMLQVLHMGLHVCQ 343 >3NV7-A nrPDB Length = 157 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 G+F+P+TN H+ D +H++ ++ E +I V S K + + R+ M +LA Sbjct: 9 GTFDPVTNGHI-------DIIHRSS--ELFEKLIVAVAHSSAKNPMFSLDERLKMIQLAT 59 Query: 73 QTSDWIRVDPWE 84 ++ + +E Sbjct: 60 KSFKNVECVAFE 71 >6CBN-A nrPDB Length = 438 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 9/91 (9%) Query: 112 DGPDPSKTPSASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFG---LVCVSRSG 168 DG + A L L LCG +V+ F++ + + E G L+ G Sbjct: 94 DGTATGWSRRVDAVLERLHALCGGEVVGLFRSGTAAVRAAVLAVREATGRPLLLSAGYHG 153 Query: 169 HDPERYISDSPI------LQQFQHNIHLARE 193 +DP Y S++P+ + F ++ L RE Sbjct: 154 YDPMWYPSEAPLEPNADGVVDFFFDLGLLRE 184 >6AYH-A nrPDB Length = 201 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 1/75 (1%) Query: 36 TGRYQ-VIEGIISPVNDSYGKKDLVASHHRVAMARLALQTSDWIRVDPWESEQAQWMETV 94 T +Y +I +++ ND+ K ++ A + ARL L T+ + D +E A+ + Sbjct: 125 TNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLATTYGVLSDSSSAENARHVSFA 184 Query: 95 KVLRHHHRELLRSSA 109 LR LL+ ++ Sbjct: 185 TTLRTMLTGLLKCNS 199 >5JBN-A nrPDB Length = 170 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 9/59 (15%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLA 71 G+F+PITN H+ + T Q+ + +I + S KK + RVA+A+ A Sbjct: 12 GTFDPITNGHIDIV---------TRATQMFDHVILAIAASPSKKPMFTLEERVALAQQA 61 >5Z9Y-A nrPDB Length = 252 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 13/57 (22%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 46 ISPVNDSYGKKDLVASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHR 102 I+P+ ++ G + + +AR AL T +W++++ E+ W + V+++R + Sbjct: 66 ITPLPNTAGSRSAAEAVLTAQLAREALNT-NWVKLEVIADERTLWPDAVELVRAAEQ 121 >6AH3-E nrPDB Length = 173 Score = 26.9 bits (58), Expect = 7.5, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (9%) Query: 37 GRYQVIEGIISP----VNDSYGKKDLVASHHRVAMARLALQT 74 RY + E I P V +S K D++ SHHR + A +++++ Sbjct: 6 SRYILFEIIFPPTDTNVEESVSKADILLSHHRASPADVSIKS 47 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5Z9R-A nrPDB 357 3e-99 1NUQ-A nrPDB 340 3e-94 1GZU-A nrPDB 294 2e-80 1YUM-A nrPDB 201 3e-52 4YMI-A nrPDB 197 5e-51 1K4M-A nrPDB 188 2e-48 2H29-A nrPDB 179 1e-45 1KAM-A nrPDB 174 3e-44 4WSO-A nrPDB 143 5e-35 Sequences not found previously or not previously below threshold: 4YBR-A nrPDB 167 4e-42 3DV2-A nrPDB 131 3e-31 3NV7-A nrPDB 41 4e-04 5O0B-A nrPDB 39 0.002 1O6B-A nrPDB 39 0.002 6JOG-A nrPDB 39 0.002 3X1M-A nrPDB 39 0.002 5LLT-A nrPDB 39 0.002 3L93-A nrPDB 38 0.003 1OD6-A nrPDB 38 0.003 3ND6-A nrPDB 38 0.004 3PXU-A nrPDB 37 0.010 5JBN-A nrPDB 36 0.010 4XMN-D nrPDB 36 0.019 3H05-A nrPDB 35 0.025 6G7T-A nrPDB 35 0.033 3NBK-A nrPDB 35 0.033 2B7L-A nrPDB 35 0.042 2X0K-A nrPDB 34 0.062 4F3R-A nrPDB 34 0.067 4NAH-A nrPDB 34 0.070 1N1D-A nrPDB 33 0.094 1F9A-A nrPDB 33 0.13 1VLH-A nrPDB 32 0.24 5Y0R-A nrPDB 31 0.44 2QJO-A nrPDB 31 0.70 3MUN-A nrPDB 30 0.92 5ZGH-F nrPDB 29 1.2 3G7Q-A nrPDB 29 1.4 5Y0N-A nrPDB 29 1.7 6FOS-F nrPDB 29 1.8 3DO8-A nrPDB 29 1.8 >5Z9R-A nrPDB Length = 281 Score = 357 bits (915), Expect = 3e-99, Method: Composition-based stats. Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA 60 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA Sbjct: 37 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA 96 Query: 61 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP 120 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP Sbjct: 97 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP 156 Query: 121 SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPI 180 SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPI Sbjct: 157 SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPI 216 Query: 181 LQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG 240 LQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG Sbjct: 217 LQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG 276 Query: 241 KGKTG 245 KGKTG Sbjct: 277 KGKTG 281 >1NUQ-A nrPDB Length = 252 Score = 340 bits (872), Expect = 3e-94, Method: Composition-based stats. Identities = 199/242 (82%), Positives = 217/242 (89%), Gaps = 1/242 (0%) Query: 1 MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVA 60 MK+RIPVVLLACGSFNPITNMHLR+FEVARDHLHQTG YQVI+GIISPVND+YGKKDL A Sbjct: 1 MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDLAA 60 Query: 61 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTP 120 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHH +LLRS QM+GPD K Sbjct: 61 SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKAL 120 Query: 121 -SASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSP 179 S AA+PELKLLCGADVLKTFQTPNLWKD HIQEIVEKFGLVCV R HDP+ YI++SP Sbjct: 121 FSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVSHDPKGYIAESP 180 Query: 180 ILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWK 239 IL+ QHNIHLA+EPV NEISATY+R+ALGQGQSVKYL+P+AVITYI+D GLY +WK Sbjct: 181 ILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWK 240 Query: 240 GK 241 GK Sbjct: 241 GK 242 >1GZU-A nrPDB Length = 290 Score = 294 bits (753), Expect = 2e-80, Method: Composition-based stats. Identities = 122/259 (47%), Positives = 175/259 (67%), Gaps = 20/259 (7%) Query: 4 RIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHH 63 + VVLLACGSFNPITNMHLRLFE+A+D+++ TGRY V++GIISPV D+Y KK L+ ++H Sbjct: 17 KTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGLIPAYH 76 Query: 64 RVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSA--QMDGP------- 114 RV MA LA + S W+ VD WES Q +W ET+KVLRHH +L S Q + P Sbjct: 77 RVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLEASDCDHQQNSPTLERPGR 136 Query: 115 --------DPSKTPS---ASAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVC 163 D S+ S + A+P++KLLCGAD+L++F PNLWK I +IV +GL+C Sbjct: 137 KRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLLESFAVPNLWKSEDITQIVANYGLIC 196 Query: 164 VSRSGHDPERYISDSPILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVI 223 V+R+G+D +++I +S +L + + NIH+ E + N+IS+T +R+AL +GQS++YL+P+ V Sbjct: 197 VTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIANDISSTKIRRALRRGQSIRYLVPDLVQ 256 Query: 224 TYIRDQGLYINDGSWKGKG 242 YI LY ++ + G Sbjct: 257 EYIEKHNLYSSESEDRNAG 275 >1YUM-A nrPDB Length = 242 Score = 201 bits (510), Expect = 3e-52, Method: Composition-based stats. Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 43/235 (18%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISP-VNDSYGKKDLVASHHRVAMA 68 L G+F+P+ H+R + ++ + E + P + + V++ R+AM Sbjct: 27 LFGGTFDPVHIGHMR------SAVEMAEQFALDELRLLPNARPPHRETPQVSAAQRLAMV 80 Query: 69 RLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPE 128 A+ + + VDP E ++ + T+ L EL AA + Sbjct: 81 ERAVAGVERLTVDPRELQRDKPSYTIDTLESVRAEL-------------------AADDQ 121 Query: 129 LKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPE-----------RYISD 177 L +L G D T + W + +++ +V + R D E R ++D Sbjct: 122 LFMLIGWDAFCGLPTWHRW-----EALLDHCHIVVLQRPDADSEPPESLRDLLAARSVAD 176 Query: 178 SPILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 L+ I + L +SAT +R LG G+SV++L+P+AV+ YI LY Sbjct: 177 PQALKGPGGQITFVWQTPL-AVSATQIRALLGAGRSVRFLVPDAVLNYIEAHHLY 230 >4YMI-A nrPDB Length = 233 Score = 197 bits (499), Expect = 5e-51, Method: Composition-based stats. Identities = 51/232 (21%), Positives = 90/232 (38%), Gaps = 38/232 (16%) Query: 12 CGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKD--LVASHHRVAMAR 69 G+F+PI N HL D R+ + E I P + K+ + + HR M Sbjct: 34 GGTFDPIHNGHLVAASEVAD------RFALDEVIFVPTGQPWQKQGRKVSPAEHRYLMTV 87 Query: 70 LALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPEL 129 +A ++ V + ++ TV L + +L Sbjct: 88 IATASNPRFTVSRADIDRGGATYTVDTLTDLR--------------------TAHPDADL 127 Query: 130 KLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHD-PERYISDSPILQQFQHNI 188 + GAD L + + W++ + KF + VSR G++ +I+ + + + Sbjct: 128 YFITGADALASILS---WENWEQLFTLAKF--IGVSRPGYELSSDHIAHAELPPD---GL 179 Query: 189 HLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYINDGSWKG 240 L P L IS+T R GQ + + YL+P+ V+ Y+ LY + +G Sbjct: 180 SLVEVPALA-ISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYSGNKGNQG 230 >1K4M-A nrPDB Length = 213 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 63/236 (26%), Positives = 97/236 (41%), Gaps = 43/236 (18%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 L G+F+P+ HL+ E + + T R +I + P + + S R M Sbjct: 7 LFGGTFDPVHYGHLKPVETLANLIGLT-RVTIIPNNVPP----HRPQPEANSVQRKHMLE 61 Query: 70 LALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPEL 129 LA+ +D E ++ T + L+ +E GPD L Sbjct: 62 LAIADKPLFTLDERELKRNAPSYTAQTLKEWRQE--------QGPDVP-----------L 102 Query: 130 KLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHD-----------PERYISDS 178 + G D L TF T + I++ L+ R G+ E +++ + Sbjct: 103 AFIIGQDSLLTFPT-----WYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHN 157 Query: 179 P--ILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 P + Q I+LA P N ISAT +R+ L G+S + LLPE V+TYI QGLY Sbjct: 158 PEDLHLQPAGKIYLAETPWFN-ISATIIRERLQNGESCEDLLPEPVLTYINQQGLY 212 >2H29-A nrPDB Length = 189 Score = 179 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 51/230 (22%) Query: 8 VLLACGSFNPITNMHLRLFEVARDHLH--QTGRYQVIEGIISPVNDSYGKKDLVASHHRV 65 ++L G FNPI H+ VA + H Q + + +SP+ + D + HR+ Sbjct: 4 IVLYGGQFNPIHTAHMI---VASEVFHELQPDEFYFLPSFMSPLKKHH---DFIDVQHRL 57 Query: 66 AMARL---ALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSA 122 M ++ L D + Q+ +T+K + H++ Sbjct: 58 TMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKD------------------- 98 Query: 123 SAALPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQ 182 EL + G D Q L K I+ + E V V+R + Sbjct: 99 ----SELYFVIGTD-----QYNQLEKWYQIEYLKEMVTFVVVNRDKNS------------ 137 Query: 183 QFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 Q N +A + +IS+T +R+ + +G+S++ L+P++V YI+ +GLY Sbjct: 138 QNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLY 187 >1KAM-A nrPDB Length = 194 Score = 174 bits (441), Expect = 3e-44, Method: Composition-based stats. Identities = 50/227 (22%), Positives = 91/227 (40%), Gaps = 45/227 (19%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQV--IEGIISPVNDSYGKKDLVASHHRVAM 67 + G+F+P N HL + A + L+Q G ++ + I P + +D S HRV M Sbjct: 11 IFGGTFDPPHNGHLLM---ANEVLYQAGLDEIWFMPNQIPPHKQN---EDYTDSFHRVEM 64 Query: 68 ARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALP 127 +LA+Q++ +++ E E+ T + Sbjct: 65 LKLAIQSNPSFKLELVEMEREGPSYTFDTV--------------------SLLKQRYPND 104 Query: 128 ELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHN 187 +L + GAD+++ K + E++ + V R G E + P+L Sbjct: 105 QLFFIIGADMIEYLP-----KWYKLDELLNLIQFIGVKRPGFHVE---TPYPLL------ 150 Query: 188 IHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYIN 234 A P E+S+T +R+ + YL+P+ V Y+ + GLY + Sbjct: 151 --FADVPEF-EVSSTMIRERFKSKKPTDYLIPDKVKKYVEENGLYES 194 >4YBR-A nrPDB Length = 201 Score = 167 bits (422), Expect = 4e-42, Method: Composition-based stats. Identities = 50/223 (22%), Positives = 83/223 (37%), Gaps = 33/223 (14%) Query: 12 CGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGK-KDLVASHHRVAMARL 70 G+F+PI HL D + + E + P + K + + A+ HR M + Sbjct: 11 GGTFDPIHYGHLVAASEVADL------FDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVI 64 Query: 71 ALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPELK 130 A ++ V + ++ T L H EL Sbjct: 65 ATASNPRFSVSRVDIDRGGPTYTKDTLADLHA--------------------LHPDSELY 104 Query: 131 LLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHNIHL 190 GAD L + + W +E+ E V VSR G++ S + Q + + L Sbjct: 105 FTTGADALASIMSWQGW-----EELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTL 159 Query: 191 AREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYI 233 P L IS+T R+ Q + + YL+P+ V+ Y+ + LY Sbjct: 160 VEIPALA-ISSTDCRQRAEQSRPLWYLMPDGVVQYVSKRRLYT 201 >4WSO-A nrPDB Length = 271 Score = 143 bits (361), Expect = 5e-35, Method: Composition-based stats. Identities = 59/247 (23%), Positives = 87/247 (35%), Gaps = 55/247 (22%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + G+F+PI + HL L D L T E ++ P Y K+D+ A+ HR+AM R Sbjct: 54 ILGGTFDPIHDGHLALARRFADVLRLT------ELVLMPAGQPYQKQDVSAAEHRLAMTR 107 Query: 70 LALQT----SDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAA 125 A + + V E E A TV+ L L A Sbjct: 108 AAAGSLVLPGVAVSVATDEIEHAGPTYTVETLERWRERL-------------------GA 148 Query: 126 LPELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVC-VSRSGHDPERYI--------- 175 L LL GAD L T W+ + F VC +R G D Sbjct: 149 DASLSLLIGADQLVRLDTWRDWR------RLFDFAHVCAATRPGFDFAAASPAVAAEIAS 202 Query: 176 --SDSPILQQFQHNIHLAREPVLNEISATYVRKALGQGQSVKYLLPE--------AVITY 225 + + +L+ L + +++AT +R L + +P+ AV Y Sbjct: 203 RQASADVLRATPAGRLLIDTTLALDVAATDIRAHLRACIARHAQVPDASAEHVSPAVWAY 262 Query: 226 IRDQGLY 232 I LY Sbjct: 263 ILQHRLY 269 >3DV2-A nrPDB Length = 201 Score = 131 bits (328), Expect = 3e-31, Method: Composition-based stats. Identities = 39/225 (17%), Positives = 78/225 (34%), Gaps = 41/225 (18%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + G+F+P HL + L+ + I P +++ + R+ M Sbjct: 6 IIGGTFDPPHYGHLLIANEVYHALNL-EEVWFLPNQIPPHKQG---RNITSVESRLQMLE 61 Query: 70 LALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPEL 129 LA + + + E + T + + + Sbjct: 62 LATEAEEHFSICLEELSRKGPSYTYDTMLQ--------------------LTKKYPDVQF 101 Query: 130 KLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHNIH 189 + G D+++ K +I+ +++ V V+R G+ + P I Sbjct: 102 HFIIGGDMVEYLP-----KWYNIEALLDLVTFVGVARPGYKLR---TPYP--------IT 145 Query: 190 LAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLYIN 234 P +S++ +R+ + ++ KYLLPE V YI GLY + Sbjct: 146 TVEIPEFA-VSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES 189 >3NV7-A nrPDB Length = 157 Score = 41.1 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 34/80 (42%), Gaps = 9/80 (11%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + G+F+P+TN H+ + + + E +I V S K + + R+ M + Sbjct: 6 IYPGTFDPVTNGHIDIIHRSSELF---------EKLIVAVAHSSAKNPMFSLDERLKMIQ 56 Query: 70 LALQTSDWIRVDPWESEQAQ 89 LA ++ + +E A Sbjct: 57 LATKSFKNVECVAFEGLLAY 76 >5O0B-A nrPDB Length = 162 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 GSF+P+T HL +FE A Q E I++ + + K + R+ M R + Sbjct: 9 GSFDPVTLGHLDVFERAAA--------QFDEVIVAVLINP-NKAGMFTVDERIEMIREST 59 Query: 73 QTSDWIRVD 81 +RV+ Sbjct: 60 ADLPNLRVE 68 >1O6B-A nrPDB Length = 169 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 9/73 (12%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 GSF+P+T HL + + Q + V ++ KK L + R + R Sbjct: 9 GSFDPVTYGHLDIIKRGAHIFEQ---------VYVCVLNNSSKKPLFSVEERCELLREVT 59 Query: 73 QTSDWIRVDPWES 85 + I V+ + Sbjct: 60 KDIPNITVETSQG 72 >6JOG-A nrPDB Length = 163 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 30/65 (46%), Gaps = 9/65 (13%) Query: 9 LLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMA 68 ++ G+F+PITN H+ L A + ++ + + K L + RVA+A Sbjct: 6 VIYPGTFDPITNGHVDLVTRASRMFDE---------VVVAIAIGHHKNPLFSLEERVALA 56 Query: 69 RLALQ 73 + +L Sbjct: 57 QSSLG 61 >3X1M-A nrPDB Length = 159 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 9/72 (12%) Query: 9 LLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMA 68 +L G+F+PIT H L E A +I V S K L + RVA+A Sbjct: 4 VLYPGTFDPITKGHGDLIERASRLFDH---------VIIAVAASPKKNPLFSLEQRVALA 54 Query: 69 RLALQTSDWIRV 80 + + + V Sbjct: 55 QEVTKHLPNVEV 66 >5LLT-A nrPDB Length = 213 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 44/232 (18%), Positives = 75/232 (32%), Gaps = 42/232 (18%) Query: 8 VLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAM 67 + + GSF+PIT H + + + + VI K L HHR M Sbjct: 6 ICIYGGSFDPITYAHEMVLDKISNLNWIHEIWVVI-------CRCRNDKSLTEFHHRHNM 58 Query: 68 ARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALP 127 + + S I ++L S D KT Sbjct: 59 FTIIINNSSKIIKSKIFL----------------KDLESHSEMTPTYDLLKTQKELHPNY 102 Query: 128 ELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHN 187 G+D++ +++ +++V + + + R + I + Sbjct: 103 TFYFGLGSDLIC-----DIFSWDEGEKLVLENAFIIIERGHFKIDESIL------KKFPK 151 Query: 188 IHLAREPVL---NEISATYVRKALGQGQSV----KYLLPEAVITYIRDQGLY 232 +L P L N IS++ RK L + + KY+ P I YI LY Sbjct: 152 YYLINIPKLSFINFISSSEARKFLTKENDINDIKKYIHP-LTIDYIIKYNLY 202 >3L93-A nrPDB Length = 162 Score = 38.4 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 9/71 (12%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + G+F+PITN HL L A +I + DS KK + RVA+A+ Sbjct: 9 IYPGTFDPITNGHLDLVTRASAMFSH---------VILAIADSSSKKPMFTLDERVALAK 59 Query: 70 LALQTSDWIRV 80 + V Sbjct: 60 KVTAPLKNVEV 70 >1OD6-A nrPDB Length = 160 Score = 38.4 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%) Query: 9 LLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMA 68 ++ GSF+P+TN HL + + A + V+E S + L ++ R+A+ Sbjct: 3 VVYPGSFDPLTNGHLDVIQRASRLFEKVT-VAVLEN------PSKRGQYLFSAEERLAII 55 Query: 69 RLALQ 73 R A Sbjct: 56 REATA 60 >3ND6-A nrPDB Length = 171 Score = 38.0 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 9/79 (11%) Query: 8 VLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAM 67 + L GSF+P+TN HL L E + +VI G+ + K+ L + + Sbjct: 4 IALFPGSFDPMTNGHLNLIERSAKLF-----DEVIIGVFI----NTSKQTLFTPEEKKYL 54 Query: 68 ARLALQTSDWIRVDPWESE 86 A + +RV E++ Sbjct: 55 IEEATKEMPNVRVIMQETQ 73 >3PXU-A nrPDB Length = 170 Score = 36.8 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 9/74 (12%) Query: 7 VVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVA 66 VV + G+F+P+T H L A + ++ V DS KK + R+ Sbjct: 6 VVAVYPGTFDPLTRGHEDLVRRASSIF---------DTLVVGVADSRAKKPFFSLEERLK 56 Query: 67 MARLALQTSDWIRV 80 +A L ++V Sbjct: 57 IANEVLGHYPNVKV 70 >5JBN-A nrPDB Length = 170 Score = 36.4 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 9/64 (14%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + G+F+PITN H+ + A +I + S KK + RVA+A+ Sbjct: 9 IYPGTFDPITNGHIDIVTRATQMFDH---------VILAIAASPSKKPMFTLEERVALAQ 59 Query: 70 LALQ 73 A Sbjct: 60 QATA 63 >4XMN-D nrPDB Length = 685 Score = 35.7 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 17/135 (12%), Positives = 38/135 (28%), Gaps = 8/135 (5%) Query: 81 DPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPELKLLCGADVLKT 140 D E + ++ R +L+ S + + + L+ G + K Sbjct: 228 DSIELLKQYPKDSSSTFREWKNLVLKLSQAFGSSATDISGELRDYIEDFLLVIGGNQRKI 287 Query: 141 FQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHNIHLAREPVLNEIS 200 Q W ++ G + + L+ +I E +I Sbjct: 288 LQYSRTWYESF-------CGFLLYYIPSLELSAE-YLQMSLEANVVDITNDWEQPCVDII 339 Query: 201 ATYVRKALGQGQSVK 215 + + L +S+ Sbjct: 340 SGKIHSILPVMESLD 354 >3H05-A nrPDB Length = 177 Score = 35.3 bits (79), Expect = 0.025, Method: Composition-based stats. Identities = 31/225 (13%), Positives = 65/225 (28%), Gaps = 58/225 (25%) Query: 8 VLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAM 67 + + +FNP + H + E ++ P K+++ R + Sbjct: 4 IAIFGSAFNPPSLGHKSVIESLS---------HFDLVLLEPSIAHAWGKNMLDYPIRCKL 54 Query: 68 ARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALP 127 ++ V + EQA L + + + Sbjct: 55 VDAFIKDMGLSNVQRSDLEQA---------------LYQPGQSVTTYALLEKIQEIYPTA 99 Query: 128 ELKLLCGADVLKTFQTPNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHN 187 ++ + G D F K +EI E++ ++ Sbjct: 100 DITFVIGPDNFFKFA-----KFYKAEEITERWTVMAC----------------------- 131 Query: 188 IHLAREPVLNEISATYVRKALGQGQSVKYLLPEAVITYIRDQGLY 232 P +I +T +R AL +G+ + V + ++GLY Sbjct: 132 ------PEKVKIRSTDIRNALIEGKDISTYTTPTVSELLLNEGLY 170 >6G7T-A nrPDB Length = 163 Score = 34.9 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 GSF+P+T H+ +FE A + V+ +++P K + R+AM + + Sbjct: 10 GSFDPVTLGHVDIFERAAAQFDEV----VVAILVNPA-----KTGMFDLDERIAMVKEST 60 Query: 73 QTSDWIRVD 81 +RV Sbjct: 61 THLPNLRVQ 69 >3NBK-A nrPDB Length = 177 Score = 34.9 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 GSF+P+T H+ +FE A + V+ +++P K + R+AM + + Sbjct: 28 GSFDPVTLGHVDIFERAAAQFDEV----VVAILVNPA-----KTGMFDLDERIAMVKEST 78 Query: 73 QTSDWIRVD 81 +RV Sbjct: 79 THLPNLRVQ 87 >2B7L-A nrPDB Length = 132 Score = 34.5 bits (77), Expect = 0.042, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 20/57 (35%), Gaps = 4/57 (7%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 G+++ + H+ L AR+ G Y ++ N KK R M Sbjct: 8 GTYDLLHYGHIELLRRAREM----GDYLIVALSTDEFNQIKHKKSYYDYEQRKMMLE 60 >2X0K-A nrPDB Length = 338 Score = 34.1 bits (76), Expect = 0.062, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 40/125 (32%), Gaps = 7/125 (5%) Query: 13 GSFNPITNMHLRL----FEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMA 68 G F+ + H +L E AR+ + +S + R A+A Sbjct: 22 GVFDGVHRGHQKLINATVEKAREVGAKAIMVTFDPHPVSVFLPRRAPLGITTLAERFALA 81 Query: 69 RLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPE 128 + E + V+ L + L +S + G + + +A+ Sbjct: 82 ESFGIDGVLVIDFTRELSGTSPEKYVEFL---LEDTLHASHVVVGANFTFGENAAGTADS 138 Query: 129 LKLLC 133 L+ +C Sbjct: 139 LRQIC 143 >4F3R-A nrPDB Length = 162 Score = 33.7 bits (75), Expect = 0.067, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 32/83 (38%), Gaps = 15/83 (18%) Query: 3 NRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASH 62 N + + + G+F+P+TN H+ + E A ++ II + K + Sbjct: 2 NAMKPIAIYPGTFDPLTNGHVDIIERALPLFNK---------IIVACAPTSRKDPHLKLE 52 Query: 63 HRVAMARLALQTSDWIRVDPWES 85 RV + +D + + E Sbjct: 53 ERVNLI------ADVLTDERVEV 69 >4NAH-A nrPDB Length = 160 Score = 33.7 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 9/68 (13%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 GSF+PIT HL + E + T R+ I + + K+ + R+ + ++ Sbjct: 10 GSFDPITYGHLDIIERS------TDRFDEIHVCVL---KNSKKEGTFSLEERMDLIEQSV 60 Query: 73 QTSDWIRV 80 + ++V Sbjct: 61 KHLPNVKV 68 >1N1D-A nrPDB Length = 129 Score = 33.4 bits (74), Expect = 0.094, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 G+F+ + H++L E A+ Q G Y V+ N KK + HR + Sbjct: 8 GTFDLLHWGHIKLLERAK----QLGDYLVVAISTDEFNLQKQKKAYHSYEHRKLILETIR 63 Query: 73 QTSDWIRVDPWESEQ 87 + I WE ++ Sbjct: 64 YVDEVIPEKNWEQKK 78 >1F9A-A nrPDB Length = 168 Score = 33.0 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 21/33 (63%) Query: 196 LNEISATYVRKALGQGQSVKYLLPEAVITYIRD 228 E S T +R+ + G+ ++L+P+AV+ I++ Sbjct: 121 RKEYSGTEIRRRMLNGEKWEHLVPKAVVDVIKE 153 Score = 29.9 bits (65), Expect = 1.00, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 24/65 (36%), Gaps = 6/65 (9%) Query: 13 GSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLAL 72 G F P HL + + + + ++I GI S + A R+ M +L Sbjct: 7 GRFQPFHKGHLEVIKKIAEEV-----DEIIIGIGSAQKSHTLENPFTAGE-RILMITQSL 60 Query: 73 QTSDW 77 + D Sbjct: 61 KDYDL 65 >1VLH-A nrPDB Length = 173 Score = 32.2 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 28/72 (38%), Gaps = 9/72 (12%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + GSF+PIT H+ + + A E ++ + KK + R + Sbjct: 16 VYPGSFDPITLGHVDIIKRALSIF--------DELVVLVTENP-RKKCMFTLEERKKLIE 66 Query: 70 LALQTSDWIRVD 81 L D ++VD Sbjct: 67 EVLSDLDGVKVD 78 >5Y0R-A nrPDB Length = 425 Score = 31.0 bits (68), Expect = 0.44, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 17/53 (32%) Query: 15 FNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAM 67 +NP N HL AR+ + V+ G + + + M Sbjct: 10 YNPFHNGHLYHLTSARELVKPDYTIAVMSGNFCQRGEPAVIDKFARAEIALRM 62 >2QJO-A nrPDB Length = 341 Score = 30.7 bits (67), Expect = 0.70, Method: Composition-based stats. Identities = 37/224 (16%), Positives = 68/224 (30%), Gaps = 71/224 (31%) Query: 10 LACGSFNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMAR 69 + G F P HLR +A + Q + + + + S R+AM Sbjct: 11 IYIGRFQPFHLGHLRTLNLALEKAEQVIIILGSHRVAADTRNPWR------SPERMAMIE 64 Query: 70 LALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPEL 129 L + ++L+ H Sbjct: 65 ACL--------------------SPQILKRVH---------------------------- 76 Query: 130 KLLCGADVLKTFQTPNLWKDTHIQEIVEKFG----LVCVSRSGHDPERYISDSPILQQFQ 185 L D L + NLW Q++++ G +V + GH + + Q+ Sbjct: 77 -FLTVRDWLYS---DNLWLAAVQQQVLKITGGSNSVVVL---GHRKDASSYYLNLFPQWD 129 Query: 186 HNIHLAREPVLNEISATYVRKALGQGQSVKYL--LPEAVITYIR 227 + S+T +R A +G+ YL +P A+ Y++ Sbjct: 130 ----YLETGHYPDFSSTAIRGAYFEGKEGDYLDKVPPAIADYLQ 169 >3MUN-A nrPDB Length = 693 Score = 30.3 bits (66), Expect = 0.92, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 23/60 (38%) Query: 34 HQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLALQTSDWIRVDPWESEQAQWMET 93 + + +SP + + + R+ L+L SDW + + E Q +ET Sbjct: 111 GKPAEVFLDPNTLSPDGTTALDQLSFSRDGRILAYSLSLAGSDWREIHLMDVESKQPLET 170 >5ZGH-F nrPDB Length = 185 Score = 29.5 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 28/111 (25%) Query: 84 ESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPELKLLCGADVLKTFQT 143 E+ + + V+ L + +S LLCG D L T Sbjct: 38 EAFHKREINEVRTLENRQANYEANSPSYLALQSQIDQVHKRFDKYGTLLCGQDGLPHLIT 97 Query: 144 PNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHNIHLAREP 194 W+ I L G Y+ + + + P Sbjct: 98 DGDWRHAREFTIPALLFLYITGWIGWVGRSYLKYTKETKNPTEQEIILDVP 148 >3G7Q-A nrPDB Length = 417 Score = 29.5 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 16/118 (13%), Positives = 36/118 (30%), Gaps = 7/118 (5%) Query: 80 VDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPELKLLCGADVLK 139 + Q+ + + + + S +L + ++ Sbjct: 101 IALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDL-FVSARPNIE 159 Query: 140 TFQTPNLWKDTHIQEIV--EKFGLVCVSRSGHDPERYISDSPILQ----QFQHNIHLA 191 + + E+ G++CVSR + I+D +++ QHNI L Sbjct: 160 LLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLV 217 >5Y0N-A nrPDB Length = 435 Score = 29.1 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 25/68 (36%), Gaps = 7/68 (10%) Query: 15 FNPITNMHLRLFEVARDHLHQTGRYQVIEGIISPVNDSYGKKDLVASHHRVAMARLALQT 74 +NP N HL + A+ V+ G + A + A ++ALQ+ Sbjct: 30 YNPFHNGHLYHAQTAKLQTGCDTAVAVMSGHFLQRGEP-------AVVSKWARTKMALQS 82 Query: 75 SDWIRVDP 82 + ++ Sbjct: 83 GVDLVIEL 90 >6FOS-F nrPDB Length = 155 Score = 29.1 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 28/111 (25%) Query: 84 ESEQAQWMETVKVLRHHHRELLRSSAQMDGPDPSKTPSASAALPELKLLCGADVLKTFQT 143 E+ + + V+ L + +S LLCG D L T Sbjct: 8 EAFHKREINEVRTLENRQANYEANSPSYLALQSQIDQVHKRFDKYGTLLCGQDGLPHLIT 67 Query: 144 PNLWKDTHIQEIVEKFGLVCVSRSGHDPERYISDSPILQQFQHNIHLAREP 194 W+ I L G Y+ + + + P Sbjct: 68 DGDWRHAREFTIPALLFLYITGWIGWVGRSYLKYTKETKNPTEQEIILDVP 118 >3DO8-A nrPDB Length = 148 Score = 29.1 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 7/18 (38%), Positives = 11/18 (61%) Query: 12 CGSFNPITNMHLRLFEVA 29 G+F P+ H +L +VA Sbjct: 6 GGTFEPLHEGHKKLIDVA 23 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.114 0.275 Lambda K H 0.267 0.0347 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,158,963 Number of Sequences: 36641 Number of extensions: 273682 Number of successful extensions: 923 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 43 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 829 Number of HSP's gapped (non-prelim): 76 length of query: 245 length of database: 10,336,785 effective HSP length: 94 effective length of query: 151 effective length of database: 6,892,531 effective search space: 1040772181 effective search space used: 1040772181 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.8 bits)