BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q99895 (268 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4H4F-A nrPDB 497 e-141 1PYT-D nrPDB 421 e-118 1BRU-P nrPDB 305 1e-83 1FON-A nrPDB 270 4e-73 1ELT-A nrPDB 256 6e-69 2V35-A nrPDB 250 4e-67 2CGA-A nrPDB 181 2e-46 2F83-A nrPDB 156 7e-39 5TJX-A nrPDB 153 7e-38 6I44-A nrPDB 152 1e-37 5UGG-A nrPDB 150 6e-37 1FIZ-A nrPDB 149 2e-36 3T2N-A nrPDB 147 3e-36 6AOD-C nrPDB 147 4e-36 4DUR-A nrPDB 147 6e-36 3W94-A nrPDB 146 8e-36 1LTO-A nrPDB 144 3e-35 1P57-B nrPDB 143 1e-34 4MPW-A nrPDB 142 2e-34 5GVT-A nrPDB 139 1e-33 1EKB-B nrPDB 139 1e-33 1FIW-A nrPDB 136 8e-33 3LC3-A nrPDB 136 1e-32 4DGJ-A nrPDB 135 2e-32 3P8G-A nrPDB 132 1e-31 1X7A-C nrPDB 132 2e-31 1EQ9-A nrPDB 131 4e-31 3DFJ-A nrPDB 131 4e-31 3E0N-B nrPDB 130 4e-31 1EUF-A nrPDB 129 9e-31 1C5M-D nrPDB 128 3e-30 1FI8-A nrPDB 127 7e-30 2F91-A nrPDB 126 1e-29 2BDH-A nrPDB 125 2e-29 2XRC-A nrPDB 125 2e-29 1YC0-A nrPDB 125 2e-29 1KIG-H nrPDB 124 5e-29 1NN6-A nrPDB 124 5e-29 2OQ5-A nrPDB 123 1e-28 4AN7-A nrPDB 122 1e-28 2R0L-A nrPDB 122 2e-28 1AZZ-A nrPDB 122 2e-28 2XXL-A nrPDB 121 3e-28 1M9U-A nrPDB 120 5e-28 1F7Z-A nrPDB 120 6e-28 1FUJ-A nrPDB 120 6e-28 1A5I-A nrPDB 120 8e-28 3RP2-A nrPDB 119 1e-27 5O32-I nrPDB 119 1e-27 5FXL-A nrPDB 119 1e-27 4J1Y-A nrPDB 119 1e-27 1UTJ-A nrPDB 119 2e-27 2OLG-A nrPDB 119 2e-27 1ELV-A nrPDB 119 2e-27 2ZKS-A nrPDB 117 4e-27 1A0J-A nrPDB 117 7e-27 1BDA-A nrPDB 116 9e-27 4BXW-A nrPDB 116 1e-26 1FDP-A nrPDB 116 1e-26 4IGD-A nrPDB 116 1e-26 5LHN-A nrPDB 115 2e-26 2RDL-A nrPDB 114 6e-26 1SC8-U nrPDB 114 7e-26 3G01-A nrPDB 113 8e-26 1FXY-A nrPDB 113 8e-26 3TK9-A nrPDB 112 1e-25 2TLD-E nrPDB 112 2e-25 3QUM-P nrPDB 112 2e-25 2EEK-A nrPDB 110 4e-25 4KKD-A nrPDB 110 6e-25 2HLC-A nrPDB 110 7e-25 1MKW-K nrPDB 110 9e-25 3F6U-H nrPDB 108 2e-24 1PPF-E nrPDB 108 2e-24 5UBM-A nrPDB 107 4e-24 5C67-A nrPDB 107 6e-24 4WWY-A nrPDB 107 7e-24 1ETT-H nrPDB 105 2e-23 4XDE-A nrPDB 105 2e-23 4NFE-A nrPDB 105 3e-23 1ORF-A nrPDB 104 3e-23 3NXP-A nrPDB 103 7e-23 3K65-B nrPDB 103 9e-23 2JET-B nrPDB 103 9e-23 2OCV-B nrPDB 103 1e-22 4NZQ-A nrPDB 103 1e-22 4Z6A-H nrPDB 102 2e-22 1KYN-A nrPDB 102 2e-22 4IW4-E nrPDB 102 3e-22 1VR1-H nrPDB 101 3e-22 4Q7Y-A nrPDB 101 3e-22 1IAU-A nrPDB 100 4e-22 1SPJ-A nrPDB 100 5e-22 5FCR-A nrPDB 100 7e-22 4DJZ-B nrPDB 100 9e-22 5KWM-A nrPDB 100 1e-21 1SGF-G nrPDB 100 1e-21 5TO3-B nrPDB 100 1e-21 5MS3-A nrPDB 98 4e-21 1NPM-A nrPDB 97 5e-21 6BQM-A nrPDB 97 1e-20 1YM0-A nrPDB 95 2e-20 2B9L-A nrPDB 95 3e-20 1AO5-A nrPDB 95 3e-20 1SGF-A nrPDB 95 3e-20 2ASU-B nrPDB 95 4e-20 2PSX-A nrPDB 94 4e-20 5ZFH-A nrPDB 94 5e-20 6QHB-A nrPDB 92 2e-19 1TON-A nrPDB 92 2e-19 1Q3X-A nrPDB 92 2e-19 1MZD-A nrPDB 92 3e-19 3VGC-B nrPDB 92 3e-19 1ZJK-A nrPDB 90 1e-18 1MD7-A nrPDB 89 1e-18 1GPZ-A nrPDB 89 3e-18 1GVZ-A nrPDB 88 4e-18 3BSQ-A nrPDB 87 8e-18 4FXG-H nrPDB 87 9e-18 4LK4-A nrPDB 86 2e-17 3S9B-A nrPDB 84 6e-17 3RU4-E nrPDB 84 7e-17 1AE5-A nrPDB 83 1e-16 1SI5-H nrPDB 82 2e-16 4E7N-A nrPDB 81 4e-16 2QY0-B nrPDB 80 9e-16 2AIQ-A nrPDB 79 1e-15 1PQ7-A nrPDB 79 2e-15 3I77-A nrPDB 78 4e-15 5LPF-A nrPDB 78 4e-15 4WJG-C nrPDB 78 4e-15 2JET-C nrPDB 78 5e-15 4GSO-A nrPDB 78 5e-15 1BQY-A nrPDB 77 7e-15 2FMJ-A nrPDB 77 8e-15 1OP0-A nrPDB 76 2e-14 5XW8-A nrPDB 75 2e-14 4X0L-C nrPDB 75 3e-14 4F4O-C nrPDB 74 5e-14 5XRF-A nrPDB 74 6e-14 3BEU-A nrPDB 74 8e-14 1BBR-H nrPDB 73 1e-13 1RIW-B nrPDB 72 3e-13 3S69-A nrPDB 71 5e-13 2PKA-B nrPDB 68 5e-12 3H7O-A nrPDB 67 7e-12 3H5C-B nrPDB 60 1e-09 3F1S-B nrPDB 60 1e-09 1DLE-A nrPDB 60 1e-09 2WIN-I nrPDB 59 2e-09 2OK5-A nrPDB 59 3e-09 3H7T-A nrPDB 54 9e-08 1AKS-B nrPDB 53 2e-07 2KAI-A nrPDB 51 7e-07 2I6S-A nrPDB 50 1e-06 2HNT-E nrPDB 48 5e-06 1BBR-E nrPDB 42 3e-04 2HNT-F nrPDB 42 4e-04 1EPT-B nrPDB 40 7e-04 2HNT-C nrPDB 37 0.006 1P3E-A nrPDB 32 0.39 4V8P-BH nrPDB 27 7.7 >4H4F-A nrPDB Length = 249 Score = 497 bits (1279), Expect = e-141, Method: Compositional matrix adjust. Identities = 239/239 (100%), Positives = 239/239 (100%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 180 Query: 210 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL Sbjct: 181 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 239 >1PYT-D nrPDB Length = 251 Score = 421 bits (1083), Expect = e-118, Method: Compositional matrix adjust. Identities = 202/252 (80%), Positives = 224/252 (88%), Gaps = 1/252 (0%) Query: 17 CGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI 76 CG P F PNLSARVVGGEDA PHSWPWQISLQYL+++TWRHTCGGTLI N VLTAAHCI Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 77 SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDT 136 SNT TYRVA+GKNNLEVEDE GSL+VGVDTI VH++WN+ L+RNDIALIKLAE VEL DT Sbjct: 61 SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDT 120 Query: 137 IQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 IQVACLP + SLLP+DYPC+VTGWGRL+TNGPIA +LQQGLQPVVD+ATCS+ DWWG V Sbjct: 121 IQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTV 180 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 K+TMVCAGGDGVISACNGDSGGPLNCQ +G W+V GIVSFGS CNT KKP V+TRVS Sbjct: 181 KETMVCAGGDGVISACNGDSGGPLNCQ-ADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVS 239 Query: 257 AYIDWINEKMQL 268 AYIDWIN+K+QL Sbjct: 240 AYIDWINQKLQL 251 >1BRU-P nrPDB Length = 241 Score = 305 bits (781), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 150/237 (63%), Positives = 179/237 (75%), Gaps = 3/237 (1%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGGEDARP+SWPWQ+SLQY + WRHTCGGTL+ ++VLTAAHCIS++RTYRV +G++ Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN--DIALIKLAEHVELSDTIQVACLPEKDS 147 +L +E GSL V V + VH+ WN+ L N DIAL+KLA V L+D IQ+ CLP + Sbjct: 61 SLST-NEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGT 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +LP +Y CYVTGWGRL TNG D LQQG VVD+ATCS+ WWG VK M+CAGGDG Sbjct: 120 ILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDG 179 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +IS+CNGDSGGPLNCQ NG W+V GIVSFGS GCN KP V+TRVS YIDWIN Sbjct: 180 IISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINS 236 >1FON-A nrPDB Length = 240 Score = 270 bits (691), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 131/237 (55%), Positives = 169/237 (71%), Gaps = 4/237 (1%) Query: 33 GEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLE 92 GEDA P+SW WQ+SLQY K+ + HTCGG+LIA ++V+TA HCIS +RTY+V +G+ + Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRS 61 Query: 93 V-EDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 V E E + + + VH WN+ + NDIAL+KL+ +L D +Q+A LP +L Sbjct: 62 VLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDIL 121 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 P + PCY++GWGRL+T GP+ DKLQQ L P VD+ CS+ DWWG VKKTMVCAGGD Sbjct: 122 PNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGD-TR 180 Query: 210 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S CNGDSGGPLNC +GSW+V G+ SF S GCNT KKP V+TRVSA+IDWI+E + Sbjct: 181 SGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 >1ELT-A nrPDB Length = 236 Score = 256 bits (655), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 124/239 (51%), Positives = 164/239 (68%), Gaps = 5/239 (2%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG A+P+SWPWQISLQY ++ HTCGG+LI +V+TAAHC+ + RT+RV +G++ Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 NL + + + V+++ +H WN+ + DIAL++L L+ +Q+A LP + Sbjct: 61 NLNTNEGKEQIMT-VNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQ 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +LP + PCY+TGWG+ T GP++D L+Q P VDHATCS WWG VK TMVCAGG G Sbjct: 120 ILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG-G 178 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S CNGDSGGPLNCQ+ NGS+ V G+ SF S GCN KKP V+TRVSAYI W+N M Sbjct: 179 ANSGCNGDSGGPLNCQV-NGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >2V35-A nrPDB Length = 240 Score = 250 bits (639), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 125/237 (52%), Positives = 159/237 (67%), Gaps = 4/237 (1%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG +A+ +SWP QISLQY +W HTCGGTLI N+V+TAAHC+ T+RV VG++ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 NL +++ +VGV I VH WN + DIAL++LA+ V L+ +Q+ LP + Sbjct: 61 NLN-QNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGT 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +L + PCY+TGWG TNG +A LQQ P VD+A CS +WG VK +MVCAGGDG Sbjct: 120 ILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDG 179 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 V S C GDSGGPL+C L NG + V G+ SF SR GCN +KP V+TRVSAYI WIN Sbjct: 180 VRSGCQGDSGGPLHC-LVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINN 235 >2CGA-A nrPDB Length = 245 Score = 181 bits (460), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 102/253 (40%), Positives = 146/253 (57%), Gaps = 14/253 (5%) Query: 17 CGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAH 74 CGVP+ P LS +R+V GE+A P SWPWQ+SLQ + T H CGG+LI N+V+TAAH Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAH 57 Query: 75 CISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELS 134 C T V V + E + + + + ++N+L + NDI L+KL+ S Sbjct: 58 C--GVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS 115 Query: 135 DTIQVACLPEKDSLLPKDYPCYVTGWGRL-WTNGPIADKLQQGLQPVVDHATCSRIDWWG 193 T+ CLP C TGWG +TN D+LQQ P++ + C + +WG Sbjct: 116 QTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKK--YWG 173 Query: 194 FRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYT 253 ++K M+CAG GV S+C GDSGGPL C+ +NG+W + GIVS+GS C+T P VY Sbjct: 174 TKIKDAMICAGASGV-SSCMGDSGGPLVCK-KNGAWTLVGIVSWGSST-CST-STPGVYA 229 Query: 254 RVSAYIDWINEKM 266 RV+A ++W+ + + Sbjct: 230 RVTALVNWVQQTL 242 >2F83-A nrPDB Length = 625 Score = 156 bits (395), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 94/247 (38%), Positives = 137/247 (55%), Gaps = 10/247 (4%) Query: 25 NLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRT 81 + R+VGG + WPWQ++L + + T RH CGG++I + ++LTAAHC + + + Sbjct: 383 KIKPRIVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI 441 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 RV G N + E +E + F GV I +H ++ DIAL+KL V +D+ + C Sbjct: 442 LRVYSGILN-QSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPIC 500 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 LP K C+VTGWG I + LQ+ P+V + C + + G ++ M+ Sbjct: 501 LPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHKMI 559 Query: 202 CAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 CAG +G AC GDSGGPL+C+ N W + GI S+G GC R++P VYT V Y+D Sbjct: 560 CAGYREGGKDACKGDSGGPLSCK-HNEVWHLVGITSWG--EGCAQRERPGVYTNVVEYVD 616 Query: 261 WINEKMQ 267 WI EK Q Sbjct: 617 WILEKTQ 623 >5TJX-A nrPDB Length = 263 Score = 153 bits (387), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 97/246 (39%), Positives = 138/246 (56%), Gaps = 12/246 (4%) Query: 27 SARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRTYR 83 S R+VGG ++ WPWQ+SLQ +K RH CGG+LI +VLTAAHC +R Sbjct: 13 STRIVGGTESSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 71 Query: 84 VAVGKNNLEVED-EEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142 + G LE+ D + + F + I +H+ + +DIALIKL +E ++ + L Sbjct: 72 IYSGI--LELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISL 129 Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 P K C+VTGWG G I + LQ+ P+V + C + + +++ + MVC Sbjct: 130 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVC 188 Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG +G AC GDSGGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+DW Sbjct: 189 AGYKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDW 245 Query: 262 INEKMQ 267 I EK Q Sbjct: 246 ILEKTQ 251 >6I44-A nrPDB Length = 627 Score = 152 bits (384), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 95/246 (38%), Positives = 138/246 (56%), Gaps = 12/246 (4%) Query: 27 SARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRTYR 83 S R+VGG + WPWQ+SLQ +K RH CGG+LI +VLTAAHC +R Sbjct: 377 STRIVGGTQSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 435 Query: 84 VAVGKNNLEVED-EEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142 + G L++ D + + F + I +H+ + +DIALIKL ++ ++ + CL Sbjct: 436 IYSGI--LQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICL 493 Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 P K C+VTGWG G I + LQ+ P+V + C + + +++ + MVC Sbjct: 494 PSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVC 552 Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG +G AC GD+GGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+DW Sbjct: 553 AGYKEGGKDACKGDAGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDW 609 Query: 262 INEKMQ 267 I EK Q Sbjct: 610 ILEKTQ 615 >5UGG-A nrPDB Length = 251 Score = 150 bits (378), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 100/263 (38%), Positives = 141/263 (53%), Gaps = 21/263 (7%) Query: 11 LACASSCGVPSF-PPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 A + CG P P RVVGG A PHSWPWQ+SL + H CGGTLI+ +V Sbjct: 2 FAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSL---RTRFGMHFCGGTLISPEWV 58 Query: 70 LTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126 LTAAHC+ + +Y+V +G + +E +L V I V R R DIAL+K Sbjct: 59 LTAAHCLEKSPRPSSYKVILGAH------QEVNLEPHVQEIEV-SRLFLEPTRKDIALLK 111 Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHAT 185 L+ ++D + ACLP + ++ C++TGWG T G A L++ PV+++ Sbjct: 112 LSSPAVITDKVIPACLPSPNYVVADRTECFITGWGE--TQGTFGAGLLKEAQLPVIENKV 169 Query: 186 CSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCN 244 C+R ++ RV+ T +CAG G +C GDSGGPL C E + + G+ S+G GC Sbjct: 170 CNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC-FEKDKYILQGVTSWG--LGCA 226 Query: 245 TRKKPVVYTRVSAYIDWINEKMQ 267 KP VY RVS ++ WI M+ Sbjct: 227 RPNKPGVYVRVSRFVTWIEGVMR 249 >1FIZ-A nrPDB Length = 263 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 98/252 (38%), Positives = 135/252 (53%), Gaps = 19/252 (7%) Query: 30 VVGGEDARPHSWPWQISLQYL--KNDTWRHTCGGTLIASNFVLTAAHCISNTRT---YRV 84 VVGG A P +WPW +SLQ N+ HTCGG L+ S++VLTAAHC N + +R+ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 85 AVGKN------NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQ 138 G N N V+ F V+ I +H+++ + L NDIALIK+ V I Sbjct: 61 IFGANEVVWGSNKPVKPPLQERF--VEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIG 118 Query: 139 VACLPEKDSLLPK-DYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRV 196 CLP+ + P+ C+VTGWG L GP + LQ+ ++D C+ W+ R+ Sbjct: 119 PGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRI 178 Query: 197 KKTMVCAG-GDGVISACNGDSGGPLNCQ-LENGSWEVFGIVSFGSRRGCNTRKKPVVYTR 254 + T VCAG G I C GDSGGPL C+ ++ V GI S+G GC K+P VYT Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV--GCARAKRPGVYTS 236 Query: 255 VSAYIDWINEKM 266 Y++WI K+ Sbjct: 237 TWPYLNWIASKI 248 >3T2N-A nrPDB Length = 372 Score = 147 bits (372), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 98/275 (35%), Positives = 141/275 (51%), Gaps = 32/275 (11%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L A CG P + R+VGG D WPWQ+SL+Y H CGG+L++ ++V Sbjct: 101 LAAICQDCGRRKLPVD---RIVGGRDTSLGRWPWQVSLRY----DGAHLCGGSLLSGDWV 153 Query: 70 LTAAHC-------ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW------NAL 116 LTAAHC +S R + AV + + L +GV + H + N+ Sbjct: 154 LTAAHCFPERNRVLSRWRVFAGAVAQASPH------GLQLGVQAVVYHGGYLPFRDPNSE 207 Query: 117 LLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQG 176 NDIAL+ L+ + L++ IQ CLP L C VTGWG G A LQ+ Sbjct: 208 ENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEA 267 Query: 177 LQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQ---LENGSWEVF 232 P++ + C+ D++G ++K M CAG +G I AC GDSGGP C+ W + Sbjct: 268 RVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLC 327 Query: 233 GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 GIVS+G+ GC +KP VYT+VS + +WI + ++ Sbjct: 328 GIVSWGT--GCALAQKPGVYTKVSDFREWIFQAIK 360 >6AOD-C nrPDB Length = 245 Score = 147 bits (372), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 90/242 (37%), Positives = 134/242 (55%), Gaps = 10/242 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTYRVAV 86 +VGG + WPWQ++L + + T RH CGG++I + ++LTAAHC + + + RV Sbjct: 1 IVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 59 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G + E +E + F GV I +H ++ DIAL+KL V+ +D+ + LP K Sbjct: 60 GILQ-QSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKG 118 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 205 C+VTGWG I + LQ+ P+V + C + + G ++ M+CAG Sbjct: 119 DRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHKMICAGYR 177 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 +G AC GD+GGPL+C+ N W + GI S+G GC R++P VYT V Y+DWI EK Sbjct: 178 EGGKDACKGDAGGPLSCK-HNEVWHLVGITSWGE--GCAQRERPGVYTNVVEYVDWILEK 234 Query: 266 MQ 267 Q Sbjct: 235 TQ 236 >4DUR-A nrPDB Length = 791 Score = 147 bits (370), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 100/264 (37%), Positives = 140/264 (53%), Gaps = 28/264 (10%) Query: 17 CGVPSF--------PPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 C PSF P RVVGG A PHSWPWQ+SL + H CGGTLI+ + Sbjct: 541 CAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSL---RTRFGMHFCGGTLISPEW 597 Query: 69 VLTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALI 125 VLTAAHC+ + +Y+V +G + +E +L V I V R R DIAL+ Sbjct: 598 VLTAAHCLEKSPRPSSYKVILGAH------QEVNLEPHVQEIEV-SRLFLEPTRKDIALL 650 Query: 126 KLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHA 184 KL+ ++D + ACLP + ++ C++TGWG T G A L++ PV+++ Sbjct: 651 KLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGE--TQGTFGAGLLKEAQLPVIENK 708 Query: 185 TCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGC 243 C+R ++ RV+ T +CAG G +C GDSGGPL C E + + G+ S+G GC Sbjct: 709 VCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC-FEKDKYILQGVTSWG--LGC 765 Query: 244 NTRKKPVVYTRVSAYIDWINEKMQ 267 KP VY RVS ++ WI M+ Sbjct: 766 ARPNKPGVYVRVSRFVTWIEGVMR 789 >3W94-A nrPDB Length = 235 Score = 146 bits (369), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 84/240 (35%), Positives = 126/240 (52%), Gaps = 13/240 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTY----RVA 85 VVGG +A +WPW +SL + RH CG +LI +++LTAAHC+ T+ Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRG----RHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAV 56 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 +G + + + VD I ++K +N DIA++ L + V ++ + CL + Sbjct: 57 LGLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASE 116 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 D P C++ GWGR G + D LQ+ P+VD C R+ + +M+CAG Sbjct: 117 DQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRL-LPEYTFTSSMLCAGY 175 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G + +C GDSGGPL C LE+ W + G+ SFG GC ++P Y RVSA+ WI E Sbjct: 176 PEGGVDSCQGDSGGPLMC-LEDARWTLIGVTSFGV--GCGRPERPGAYARVSAFTSWIAE 232 >1LTO-A nrPDB Length = 245 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 87/248 (35%), Positives = 136/248 (54%), Gaps = 22/248 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC----ISNTRTYRVA 85 +VGG++A WPWQ+SL+ +++ W H CGG+LI +VLTAAHC + + T RV Sbjct: 1 IVGGQEAPRSKWPWQVSLR-VRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQ 59 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 + + +L +D+ + V I VH ++ + DIAL++L E V +S + LP Sbjct: 60 LREQHLYYQDQ----LLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPA 115 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIAD--KLQQGLQPVVDHATCSRIDWWGFR-------V 196 P PC+VTGWG + + P+ L+Q P++++ C G + Sbjct: 116 SETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRII 175 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + M+CA G+ +C GDSGGPL C++ NG+W G+VS+ GC +P +YTRV+ Sbjct: 176 RDDMLCA-GNSQRDSCKGDSGGPLVCKV-NGTWLQAGVVSWDE--GCAQPNRPGIYTRVT 231 Query: 257 AYIDWINE 264 Y+DWI+ Sbjct: 232 YYLDWIHH 239 >1P57-B nrPDB Length = 255 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 92/255 (36%), Positives = 134/255 (52%), Gaps = 29/255 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC-------ISNTRTY 82 +VGG D WPWQ+SL+Y H CGG+L++ ++VLTAAHC +S R + Sbjct: 1 IVGGRDTSLGRWPWQVSLRY----DGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 56 Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW------NALLLRNDIALIKLAEHVELSDT 136 AV + + L +GV + H + N+ NDIAL+ L+ + L++ Sbjct: 57 AGAVAQASPH------GLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEY 110 Query: 137 IQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 IQ CLP L C VTGWG G A LQ+ P++ + C+ D++G ++ Sbjct: 111 IQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQI 170 Query: 197 KKTMVCAG-GDGVISACNGDSGGPLNCQ---LENGSWEVFGIVSFGSRRGCNTRKKPVVY 252 K M CAG +G I AC GDSGGP C+ W + GIVS+G+ GC +KP VY Sbjct: 171 KPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGVY 228 Query: 253 TRVSAYIDWINEKMQ 267 T+VS + +WI + ++ Sbjct: 229 TKVSDFREWIFQAIK 243 >4MPW-A nrPDB Length = 245 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 88/248 (35%), Positives = 134/248 (54%), Gaps = 22/248 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----SNTRTYRVA 85 +VGG++A WPWQ+SL+ + W H CGG+LI +VLTAAHC+ + RV Sbjct: 1 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 59 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 + + +L +D+ + V I VH ++ + DIAL++L E V++S + LP Sbjct: 60 LREQHLYYQDQ----LLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPA 115 Query: 146 DSLLPKDYPCYVTGWGRLWTNG--PIADKLQQGLQPVVDHATCSRIDWWGFR-------V 196 P PC+VTGWG + + P L+Q P++++ C G V Sbjct: 116 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 175 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + M+CA G+ +C GDSGGPL C++ NG+W G+VS+G GC +P +YTRV+ Sbjct: 176 RDDMLCA-GNTRRDSCQGDSGGPLVCKV-NGTWLQAGVVSWGE--GCAQPNRPGIYTRVT 231 Query: 257 AYIDWINE 264 Y+DWI+ Sbjct: 232 YYLDWIHH 239 >5GVT-A nrPDB Length = 250 Score = 139 bits (351), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 91/243 (37%), Positives = 132/243 (54%), Gaps = 12/243 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTYRVAV 86 +VGG +A WPWQ+SLQ +K + H CGG++I +VLTAAHC I +R+ Sbjct: 1 IVGGTNASLGEWPWQVSLQ-VKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYG 59 Query: 87 GKNNL-EVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 G +L E+ E S + + +H+ + DIALIKL + ++ + LP K Sbjct: 60 GILSLSEITKETPS--SRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSK 117 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 C+VTGWG G + LQ+ P+V + C + + + + K M+CAG Sbjct: 118 ADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQK-KYRDYVINKQMICAGY 176 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G AC GDSGGPL C+ +G W++ GI S+G GC + +P VYT+VS Y+DWI E Sbjct: 177 KEGGTDACKGDSGGPLVCK-HSGRWQLVGITSWG--EGCARKDQPGVYTKVSEYMDWILE 233 Query: 265 KMQ 267 K Q Sbjct: 234 KTQ 236 >1EKB-B nrPDB Length = 235 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 81/242 (33%), Positives = 129/242 (53%), Gaps = 19/242 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----SNTRTYRVA 85 +VGG D+R +WPW ++L + + CG +L++ +++++AAHC+ ++ Sbjct: 1 IVGGSDSREGAWPWVVALYFDD----QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAV 56 Query: 86 VG---KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142 +G +NL E L +D I ++ +N NDIA++ L V +D IQ CL Sbjct: 57 LGLHMASNLTSPQIETRL---IDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICL 113 Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 PE++ + P C + GWG L G AD LQ+ P++ + C + + + + MVC Sbjct: 114 PEENQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQ-QMPEYNITENMVC 172 Query: 203 AGGD-GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG + G + +C GDSGGPL CQ EN W + G+ SFG + C +P VY RV + +W Sbjct: 173 AGYEAGGVDSCQGDSGGPLMCQ-ENNRWLLAGVTSFGYQ--CALPNRPGVYARVPRFTEW 229 Query: 262 IN 263 I Sbjct: 230 IQ 231 >1FIW-A nrPDB Length = 290 Score = 136 bits (343), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 91/253 (35%), Positives = 135/253 (53%), Gaps = 21/253 (8%) Query: 30 VVGGEDARPHSWPWQISLQYL--KNDTWRHTCGGTLIASNFVLTAAHCI---SNTRTYRV 84 ++GG+DA +WPW +SLQ N+ H CGG+L+ S ++LTAAHC +R+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 85 AVGKNNLE------VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQ 138 G +E V+ + V+ I +H++++A NDIAL+K+ V I Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERY--VEKIIIHEKYSASSEANDIALMKITPPVTCGHFIG 118 Query: 139 VACLPEKDSLLPK-DYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRV 196 CLP+ + P+ C+V GWG L N + LQ+ ++D C+ W+ R+ Sbjct: 119 PGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRI 178 Query: 197 KKTMVCAG-GDGVISACNGDSGGPLNCQ--LENGSWEVFGIVSFGSRRGCNTRKKPVVYT 253 + T VCAG +G I C GDSGGPL C+ EN S+ V GI S+G GC K+P VYT Sbjct: 179 RSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAEN-SYVVVGITSWGV--GCARAKRPGVYT 235 Query: 254 RVSAYIDWINEKM 266 +Y++WI K+ Sbjct: 236 STWSYLNWIASKI 248 >3LC3-A nrPDB Length = 235 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 90/244 (36%), Positives = 135/244 (55%), Gaps = 15/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGGEDA+P +PWQ+ L N CGG+++ +++TAAHC+ V G++ Sbjct: 1 VVGGEDAKPGQFPWQVVL----NGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALL--LRNDIALIKLAEHVELSDTIQVACLPEKD- 146 N+E E E V I H +NA + +DIAL++L E + L+ + C+ +K+ Sbjct: 57 NIE-ETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 115 Query: 147 -SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 ++ K YV+GWGR++ G A LQ P+VD ATC R F + M CAG Sbjct: 116 TNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRST--KFTIYNNMFCAGF 173 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G +C GDSGGP ++E S+ + GI+S+G C + K +YT+VS Y++WI E Sbjct: 174 HEGGRDSCQGDSGGPHVTEVEGTSF-LTGIISWGEE--CAMKGKYGIYTKVSRYVNWIKE 230 Query: 265 KMQL 268 K +L Sbjct: 231 KTKL 234 >4DGJ-A nrPDB Length = 235 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 83/246 (33%), Positives = 128/246 (52%), Gaps = 19/246 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS----NTRTYRVA 85 +VGG DA+ +WPW + L Y R CG +L++S+++++AAHC+ + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDD----RLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 56 Query: 86 VG---KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142 +G K+NL L +D I ++ +N NDIA++ L V +D IQ L Sbjct: 57 LGLHMKSNLTSPQTVPRL---IDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISL 113 Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 PE++ + P C + GWG + G AD LQ+ P++ + C + + + + M+C Sbjct: 114 PEENQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQ-QMPEYNITENMIC 172 Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG +G I +C GDSGGPL CQ EN W + G+ SFG C +P VY RVS + +W Sbjct: 173 AGYEEGGIDSCQGDSGGPLMCQ-ENNRWFLAGVTSFGYE--CALPNRPGVYARVSRFTEW 229 Query: 262 INEKMQ 267 I + Sbjct: 230 IQSFLH 235 >3P8G-A nrPDB Length = 241 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 84/244 (34%), Positives = 121/244 (49%), Gaps = 16/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVA---- 85 VVGG DA WPWQ+SL L H CG +LI+ N++++AAHC + R +R + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQG---HICGASLISPNWLVSAAHCYIDDRGFRYSDPTQ 57 Query: 86 ----VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +G ++ G + I H +N DIAL++L + E S ++ C Sbjct: 58 WTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPIC 117 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 LP+ + P +VTGWG G A LQ+G V+ TC + ++ M+ Sbjct: 118 LPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENL--LPQQITPRMM 175 Query: 202 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 C G G + +C GDSGGPL+ +G G+VS+G GC R KP VYTR+ + D Sbjct: 176 CVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD--GCAQRNKPGVYTRLPLFRD 233 Query: 261 WINE 264 WI E Sbjct: 234 WIKE 237 >1X7A-C nrPDB Length = 235 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 90/244 (36%), Positives = 133/244 (54%), Gaps = 15/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGGE+A+P +PWQ+ L N CGG++I +V+TAAHCI V G+ Sbjct: 1 IVGGENAKPGQFPWQVLL----NGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEY 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR--NDIALIKLAEHVELSDTIQVACLPEKD- 146 N E E E V H +NA + + +DIAL++L E + L+ + C+ +K+ Sbjct: 57 NTE-ETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 147 -SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 ++ K YV+GWGR++ G A LQ P+VD ATC R F + M CAG Sbjct: 116 TNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRST--KFTIYSNMFCAGF 173 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G +C GDSGGP ++E S+ + GI+S+G C + K +YT+VS Y++WI E Sbjct: 174 HEGGKDSCQGDSGGPHVTEVEGTSF-LTGIISWGEE--CAVKGKYGIYTKVSRYVNWIKE 230 Query: 265 KMQL 268 K +L Sbjct: 231 KTKL 234 >1EQ9-A nrPDB Length = 222 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 90/241 (37%), Positives = 130/241 (53%), Gaps = 23/241 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI---SNTRTYRVAV 86 +VGG+DA +P+Q+SL+ + H CG +++ +N VLTAAHC+ SN +V V Sbjct: 1 IVGGKDAPVGKYPYQVSLRL----SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHV 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G N L E G ++ D + V+K ++ LLRND+AL+ L ++ +D +Q L D Sbjct: 57 GTNYLS---ESGDVYDVEDAV-VNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTND 112 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 L + PC +TGWG G + LQ+ V C R W RV + +C Sbjct: 113 EDLESN-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQW---RVIDSHICTLTK 168 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 AC+GDSGGPL + NG+ GIVSFGS C +P VYTRVS+++ WIN + Sbjct: 169 RGEGACHGDSGGPL---VANGAQ--IGIVSFGSP--C-ALGEPDVYTRVSSFVSWINANL 220 Query: 267 Q 267 + Sbjct: 221 K 221 >3DFJ-A nrPDB Length = 263 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 86/249 (34%), Positives = 127/249 (51%), Gaps = 20/249 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRVAV 86 + GG A WPWQ+S+ Y H CGG+L++ +VL+AAHC + Y V + Sbjct: 1 ITGGSSAVAGQWPWQVSITY----EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G + L+ E+ + D I H + + DIAL++L+ + S I+ LP + Sbjct: 57 GAHQLDSYSEDAKVSTLKDII-PHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAN 115 Query: 147 SLLPKDYPCYVTGWGRLWTNGPI--ADKLQQGLQPVVDHATCSRIDWWGFR------VKK 198 + P C VTGWG + + + LQQ P++ TC+ + + V++ Sbjct: 116 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQE 175 Query: 199 TMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSA 257 MVCAG +G AC GDSGGPL+C +E G W + GIVS+G C R +P VYT S+ Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVE-GLWYLTGIVSWGD--ACGARNRPGVYTLASS 232 Query: 258 YIDWINEKM 266 Y WI K+ Sbjct: 233 YASWIQSKV 241 >3E0N-B nrPDB Length = 271 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 86/249 (34%), Positives = 126/249 (50%), Gaps = 20/249 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRVAV 86 + GG A WPWQ+S+ Y H CGG+L++ +VL+AAHC + Y V + Sbjct: 1 ITGGSSAVAGQWPWQVSITY----EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G + L+ E+ + D I H + + DIAL++L+ + S I+ LP Sbjct: 57 GAHQLDSYSEDAKVSTLKDII-PHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQ 115 Query: 147 SLLPKDYPCYVTGWGRLWTNGPI--ADKLQQGLQPVVDHATCSRIDWWGFR------VKK 198 + P C VTGWG + + + LQQ P++ TC+ + + V++ Sbjct: 116 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQE 175 Query: 199 TMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSA 257 MVCAG +G AC GDSGGPL+C +E G W + GIVS+G C R +P VYT S+ Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVE-GLWYLTGIVSWGD--ACGARNRPGVYTLASS 232 Query: 258 YIDWINEKM 266 Y WI K+ Sbjct: 233 YASWIQSKV 241 >1EUF-A nrPDB Length = 227 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 85/239 (35%), Positives = 124/239 (51%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ L + K H CGG L+ +FVLTAAHC+ ++ V +G + Sbjct: 1 IIGGHEAKPHSRPYMAFLLF-KTSGKSHICGGFLVREDFVLTAAHCLGSS--INVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ +E E + V H +N L NDI L+KL +++D + LP + + Sbjct: 58 NI-MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 208 C V GWGRL N P DKLQ+ V C I + + T +CAG Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKC--IARFKNYIPFTQICAGDPSKR 174 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 ++ +GDSGGPL C NG + GIVS+G G P VYTR+S+++ WI+ M+ Sbjct: 175 KNSFSGDSGGPLVC---NGVAQ--GIVSYGRNDGTT----PDVYTRISSFLSWIHSTMR 224 >1C5M-D nrPDB Length = 255 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 129/242 (53%), Gaps = 13/242 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG++ + PWQ L +N+ + CGGT+++ ++LTAAHC+ + ++V VG Sbjct: 1 IVGGQECKDGECPWQALLINEENEGF---CGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD--- 146 N E ++E G V+ + H R+ DIA+++L + + ACLPE+D Sbjct: 58 NTE-QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAE 116 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 S L V+G+GR G + +L+ P VD +C F + + M CAG D Sbjct: 117 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSS--SFIITQNMFCAGYD 174 Query: 207 GVIS-ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 AC GDSGGP + ++ ++ V GIVS+G GC + K +YT+V+A++ WI+ Sbjct: 175 TKQEDACQGDSGGPHVTRFKD-TYFVTGIVSWGE--GCARKGKYGIYTKVTAFLKWIDRS 231 Query: 266 MQ 267 M+ Sbjct: 232 MK 233 >1FI8-A nrPDB Length = 228 Score = 127 bits (318), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 120/239 (50%), Gaps = 14/239 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ LQ + + CGG LI +FVLTAAHC + +V +G + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKIQVTLGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E E+ + V I H +N+ + NDI L+KL + S ++ LP ++ + Sbjct: 59 NIK-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 CYV GWG+L G +D LQ+ V + C + K +CAG + Sbjct: 118 KPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESY-LKNYFDKANEICAGDPKIK 176 Query: 210 SAC-NGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 A GDSGGPL C+ GIVS+G G P +T+VS ++ WI + M+ Sbjct: 177 RASFRGDSGGPLVCK-----KVAAGIVSYGQNDGST----PRAFTKVSTFLSWIKKTMK 226 >2F91-A nrPDB Length = 237 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 122/239 (51%), Gaps = 13/239 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI-----SNTRTYRV 84 +VGG DA +P+Q+S Q H CG ++ N+ +TA HC+ N ++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 85 AVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE 144 G+ ++ V +E + V I +H+ ++ LL NDI+L+KL+ + +D + LPE Sbjct: 61 VAGELDMSV-NEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPE 119 Query: 145 KDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG 204 + D VTGWG G D LQ+ P+V C R D+ + +M+CAG Sbjct: 120 QGHTATGD--VIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDC-RADYGADEILDSMICAG 176 Query: 205 -GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 +G +C GDSGGPL + GS + GIVS+G GC P VYT VS ++DWI Sbjct: 177 VPEGGKDSCQGDSGGPLAAS-DTGSTYLAGIVSWG--YGCARPGYPGVYTEVSYHVDWI 232 >2BDH-A nrPDB Length = 223 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 89/239 (37%), Positives = 125/239 (52%), Gaps = 18/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ GED PHS PWQ +L ++N+ + C G L+ +VL+AAHC N+ Y + +G + Sbjct: 1 IINGEDCSPHSQPWQAAL-VMENELF---CSGVLVHPQWVLSAAHCFQNS--YTIGLGLH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 +LE + E GS V H +N LL ND+ LIKL E V SDTI+ + + Sbjct: 55 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA 114 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA-GGDGV 208 C V+GWG L NG + LQ VV CS++ + +M CA GG Sbjct: 115 GNS--CLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKL--YDPLYHPSMFCAGGGQDQ 169 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +CNGDSGGPL C NG + G+VSFG + C P VYT + + +WI + +Q Sbjct: 170 KDSCNGDSGGPLIC---NGYLQ--GLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >2XRC-A nrPDB Length = 565 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 94/257 (36%), Positives = 138/257 (53%), Gaps = 21/257 (8%) Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75 SCGV + R+VGG+ A+ PWQ++++ D TCGG I ++LTAAHC Sbjct: 308 SCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHC 363 Query: 76 ISNTRTYRVAVGKNNLE--VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH--- 130 + ++T+R + ++ D + + VD I H+ +NA +NDIALI++ + Sbjct: 364 LRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNK 423 Query: 131 --VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR 188 EL +I AC+P L + C V+GWGR N + LQ G ++ + CS+ Sbjct: 424 KDCELPRSIP-ACVPWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLI--SNCSK 479 Query: 189 IDWWGFRV-KKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTR 246 ++G R +K M CAG DG I AC GDSGGPL C N V+G+VS+G C Sbjct: 480 --FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG--ENCGKP 535 Query: 247 KKPVVYTRVSAYIDWIN 263 + P VYT+V+ Y DWI+ Sbjct: 536 EFPGVYTKVANYFDWIS 552 >1YC0-A nrPDB Length = 283 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 82/252 (32%), Positives = 134/252 (53%), Gaps = 19/252 (7%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT---RTY 82 L R++GG + P S PW ++ Y+ + C G+L+ + +V++AAHC S++ + Sbjct: 32 LRPRIIGGSSSLPGSHPWLAAI-YIGDSF----CAGSLVHTCWVVSAAHCFSHSPPRDSV 86 Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-DIALIKLAEH----VELSDTI 137 V +G++ + F G++ + ++ + D+ LI+L + S + Sbjct: 87 SVVLGQHFFNRTTDVTQTF-GIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFV 145 Query: 138 QVACLPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 Q CLPE S P + C + GWG L N + L++ L P+V CS + +G + Sbjct: 146 QPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADI 205 Query: 197 KKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 M+CAG D AC GDSGGPL C+ +NG ++GI+S+G GC KP VYTRV Sbjct: 206 SPNMLCAGYFDCKSDACQGDSGGPLACE-KNGVAYLYGIISWGD--GCGRLHKPGVYTRV 262 Query: 256 SAYIDWINEKMQ 267 + Y+DWIN++++ Sbjct: 263 ANYVDWINDRIR 274 >1KIG-H nrPDB Length = 241 Score = 124 bits (311), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 124/242 (51%), Gaps = 13/242 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG D PWQ L +N+ + CGGT++ +VLTAAHC+ + + V VG Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGF---CGGTILNEFYVLTAAHCLHQAKRFTVRVGDR 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD--- 146 N E ++E + V+ H R+ DIA+++L + + ACLPEKD Sbjct: 58 NTE-QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAE 116 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 + L V+G+GR G ++ L+ P VD +TC F + M CAG D Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSS--SFTITPNMFCAGYD 174 Query: 207 GVIS-ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 AC GDSGGP + ++ ++ V GIVS+G GC + K VYT+VS ++ WI++ Sbjct: 175 TQPEDACQGDSGGPHVTRFKD-TYFVTGIVSWGE--GCARKGKFGVYTKVSNFLKWIDKI 231 Query: 266 MQ 267 M+ Sbjct: 232 MK 233 >1NN6-A nrPDB Length = 228 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 81/239 (33%), Positives = 121/239 (50%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + +PHS P+ L+ + ++ CGG LI NFVLTAAHC R+ V +G + Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG--RSITVTLGAH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ E+E+ + V H ++N L +DI L+KL E L+ + P + + + Sbjct: 61 NI-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 119 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD-GV 208 P C V GWGR P +D LQ+ ++D CS + ++ +C G Sbjct: 120 PPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQ---LCVGNPRKT 176 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 SA GDSGGPL C + GIVS+G + K P V+TR+S Y WIN+ +Q Sbjct: 177 KSAFKGDSGGPLLC-----AGVAQGIVSYGR----SDAKPPAVFTRISHYRPWINQILQ 226 >2OQ5-A nrPDB Length = 232 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 80/238 (33%), Positives = 120/238 (50%), Gaps = 11/238 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR-VAVGK 88 +VGG + WPWQ SLQ+ + H CG TLI + ++++AAHC + TY+ A Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGS----HRCGATLINATWLVSAAHCFT---TYKNPARWT 53 Query: 89 NNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSL 148 + V + + G+ I VH+++ DI+L +L+ V ++ + CLP+ Sbjct: 54 ASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYE 113 Query: 149 LPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 +VTG+G L +G + L+Q ++D TC+ + + M+CAG +G Sbjct: 114 FQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEG 173 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 AC GDSGGPL W + GIVS+G C KP VYTRV+A DWI K Sbjct: 174 KTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE--CAKPNKPGVYTRVTALRDWITSK 229 >4AN7-A nrPDB Length = 231 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 84/247 (34%), Positives = 131/247 (53%), Gaps = 21/247 (8%) Query: 22 FPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT 81 FP + ++VGG +S P+Q+SL ++ H CGG+LI S +V++AAHC + Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKS--R 53 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +V +G++N++V E F+ I H +N L NDI LIKL+ L+ + Sbjct: 54 IQVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 112 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVKKTM 200 LP S C ++GWG ++G L Q L+ PV+ ++C + ++ M Sbjct: 113 LPR--SCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKS--SYPGQITGNM 168 Query: 201 VCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYI 259 +C G +G +C GDSGGP+ C NG + GIVS+G GC + KP VYT+V Y+ Sbjct: 169 ICVGFLEGGKDSCQGDSGGPVVC---NGQLQ--GIVSWG--YGCAQKNKPGVYTKVCNYV 221 Query: 260 DWINEKM 266 +WI + + Sbjct: 222 NWIQQTI 228 >2R0L-A nrPDB Length = 248 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 132/248 (53%), Gaps = 19/248 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT---RTYRVAV 86 ++GG + P S PW ++ Y+ + C G+L+ + +V++AAHC S++ + V + Sbjct: 1 IIGGSSSLPGSHPWLAAI-YIGDSF----CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 55 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-DIALIKLAEH----VELSDTIQVAC 141 G++ + F G++ + ++ + D+ LI+L + S +Q C Sbjct: 56 GQHFFNRTTDVTQTF-GIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 114 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTM 200 LPE S P + C + GWG L N + L++ L P+V CS + +G + M Sbjct: 115 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 174 Query: 201 VCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYI 259 +CAG D AC GDSGGPL C+ +NG ++GI+S+G GC KP VYTRV+ Y+ Sbjct: 175 LCAGYFDCKSDACQGDSGGPLACE-KNGVAYLYGIISWGD--GCGRLHKPGVYTRVANYV 231 Query: 260 DWINEKMQ 267 DWIN++++ Sbjct: 232 DWINDRIR 239 >1AZZ-A nrPDB Length = 226 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 83/240 (34%), Positives = 127/240 (52%), Gaps = 17/240 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +A P+SWP Q +L ++ + + CGG+LI+ ++LTAAHC+ V +G + Sbjct: 1 IVGGVEAVPNSWPHQAAL-FIDD---MYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ EDE + + VH+ +N+ ++ NDIA+I+L V L+ I LP D + Sbjct: 57 NIR-EDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTD--V 113 Query: 150 PKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 TGWG + I+D L+Q P++ +A C + +G V +C G Sbjct: 114 GVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAV--YGI-VTDGNICIDSTGG 170 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 CNGDSGGPLN NG +GI SFG+ GC P +TRV+ ++DWI + + Sbjct: 171 KGTCNGDSGGPLN---YNG--LTYGITSFGAAAGCE-AGYPDAFTRVTYFLDWIQTQTGI 224 >2XXL-A nrPDB Length = 408 Score = 121 bits (303), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 84/262 (32%), Positives = 129/262 (49%), Gaps = 25/262 (9%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT--YR 83 LS RV G + + S PW L+Y + R CGG +I+ ++LTAAHC+ + Y Sbjct: 115 LSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYE 174 Query: 84 VAVGKNNLEVED---EEGS--------LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVE 132 + +G++ + E+ ++G + VG++ +H++++A + +DIAL+KL V Sbjct: 175 IRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVP 234 Query: 133 LSDTIQVACLPEKDSLLPKDYPC---YVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRI 189 I+ CLP D L K +VTGWG NG +D L Q P+ + CS+ Sbjct: 235 FQKHIKPICLPITDELKEKAEQISTYFVTGWG-TTENGSSSDVLLQANVPLQPRSACSQA 293 Query: 190 DWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLEN-GSWE----VFGIVSFGSRRGCN 244 + V + +C GG + +C GDSGGPL + G + FGIVS G C Sbjct: 294 --YRRAVPLSQLCVGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVT-CG 350 Query: 245 TRKKPVVYTRVSAYIDWINEKM 266 P +YT V Y+ WI + M Sbjct: 351 QISLPGLYTNVGEYVQWITDTM 372 >1M9U-A nrPDB Length = 241 Score = 120 bits (302), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 85/246 (34%), Positives = 125/246 (50%), Gaps = 16/246 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG +A P +PWQ+S Q ++ +W H+CG +L++S L+A+HC+ + V Sbjct: 1 VIGGTNASPGEFPWQLS-QQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG 59 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + D G+ VD+ +H+ + A NDIA++ LA + L IQ A LP ++ Sbjct: 60 LWQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNN 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCS--RIDWWGFRVKKTMVC--- 202 C ++GWGR + D LQ+ PV+ A C+ + G + +C Sbjct: 120 NDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQD 179 Query: 203 -AGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF--GSRRGCNTRKKPVVYTRVSAYI 259 AG G ACNGDSGGPLNC +G V G+ S+ S G P VYTRVSAY+ Sbjct: 180 PAGNTG---ACNGDSGGPLNC--PDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYL 234 Query: 260 DWINEK 265 WI + Sbjct: 235 GWIGDN 240 >1F7Z-A nrPDB Length = 233 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 87/248 (35%), Positives = 130/248 (52%), Gaps = 21/248 (8%) Query: 21 SFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR 80 +FP + +VGG + +S P+Q+SL ++ H CGG+LI +V++AAHC + Sbjct: 2 AFPVDDDDAIVGGYTCQENSVPYQVSL-----NSGYHFCGGSLINDQWVVSAAHCYKS-- 54 Query: 81 TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140 +V +G++N+ V E FV I H ++ L NDI LIKL+ V+L+ + Sbjct: 55 RIQVRLGEHNINVL-EGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATV 113 Query: 141 CLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVKKT 199 LP S P C ++GWG ++G L Q L P++ A C + ++ Sbjct: 114 ALPS--SCAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEA--SYPGKITDN 169 Query: 200 MVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAY 258 MVC G +G +C GDSGGP+ C NG E+ GIVS+G GC P VYT+V Y Sbjct: 170 MVCVGFLEGGKDSCQGDSGGPVVC---NG--ELQGIVSWG--YGCALPDNPGVYTKVCNY 222 Query: 259 IDWINEKM 266 +DWI + + Sbjct: 223 VDWIQDTI 230 >1FUJ-A nrPDB Length = 221 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 84/240 (35%), Positives = 124/240 (51%), Gaps = 21/240 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 87 +VGG +A+PHS P+ SLQ ++ + H CGGTLI +FVLTAAHC+ + R V +G Sbjct: 1 IVGGHEAQPHSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 59 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +N+ ++ F V + ++ ++A NDI LI+L+ LS ++ LP++D Sbjct: 60 AHNVRTQEPTQQHF-SVAQVFLNN-YDAENKLNDILLIQLSSPANLSASVATVQLPQQDQ 117 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +P C GWGR+ + P A LQ+ L V C + F ++ Sbjct: 118 PVPHGTQCLAMGWGRVGAHDPPAQVLQE-LNVTVVTFFCRPHNICTFVPRRKA------- 169 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 C GDSGGPL C +G + GI SF GC TR P +TRV+ Y+DWI ++ Sbjct: 170 --GICFGDSGGPLIC---DGIIQ--GIDSF-VIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1A5I-A nrPDB Length = 265 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 90/277 (32%), Positives = 133/277 (48%), Gaps = 36/277 (12%) Query: 16 SCGVPSFP-PNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAH 74 +CG+ + P L + D H W I Q ++ R CGG LI+S +VLTAAH Sbjct: 1 TCGLRKYKEPQLHSTGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAH 60 Query: 75 CISNT-----------RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIA 123 C + RTYRV G EE F V VHK ++ NDIA Sbjct: 61 CFQESYLPDQLKVVLGRTYRVKPG--------EEEQTF-KVKKYIVHKEFDDDTYNNDIA 111 Query: 124 LIKLAEH----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQ 178 L++L + SD+++ CLPE + LP C ++G+G+ ++ P +++L++G Sbjct: 112 LLQLKSDSPQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHV 171 Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGD-------GVISACNGDSGGPLNCQLENGSWEV 231 + + C+ + V M+CAG V AC GDSGGPL C +N + Sbjct: 172 RLYPSSRCAPKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDN-HMTL 230 Query: 232 FGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 GI+S+G GC + P VYT+V+ Y+ WI + M L Sbjct: 231 LGIISWGV--GCGEKDVPGVYTKVTNYLGWIRDNMHL 265 >3RP2-A nrPDB Length = 224 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 118/235 (50%), Gaps = 16/235 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG ++ PHS P+ L + R CGG LI+ FVLTAAHC R V +G + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC--KGREITVILGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 ++ + E + V+ +H+ +N++ +DI L+KL + VEL+ + V LP + Sbjct: 59 DVR-KRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFI 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 C+ GWG+ P + L++ ++D C ++ ++ + VC G + Sbjct: 118 HPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQ---VCVGSPTTL 174 Query: 210 -SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 +A GDSGGPL C + GIVS+G K P ++TRVS Y+ WIN Sbjct: 175 RAAFMGDSGGPLLC-----AGVAHGIVSYGHPDA----KPPAIFTRVSTYVPWIN 220 >5O32-I nrPDB Length = 244 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 89/243 (36%), Positives = 131/243 (53%), Gaps = 21/243 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG+ A+ PWQ++++ D TCGG I ++LTAAHC+ ++T+R + Sbjct: 1 IVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 56 Query: 90 NLE--VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH-----VELSDTIQVACL 142 ++ D + + VD I H+ +NA +NDIALI++ + EL +I AC+ Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP-ACV 115 Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRV-KKTMV 201 P L + C V+GWGR N + LQ G ++ + CS+ +G R +K M Sbjct: 116 PWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLI--SNCSKF--YGNRFYEKEME 170 Query: 202 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 CAG DG I AC GDSGGPL C N V+G+VS+G C + P VYT+V+ Y D Sbjct: 171 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN--CGKPEFPGVYTKVANYFD 228 Query: 261 WIN 263 WI+ Sbjct: 229 WIS 231 >5FXL-A nrPDB Length = 246 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 130/248 (52%), Gaps = 21/248 (8%) Query: 21 SFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR 80 +FP + ++VGG ++ P+Q+SL ++ H CGG+LI S +V++AAHC + Sbjct: 15 AFPVDDDDKIVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKS-- 67 Query: 81 TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140 +V +G++N+ V E F+ VH +N+ L NDI LIKL L+ + Sbjct: 68 GIQVRLGEDNINVV-EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASI 126 Query: 141 CLPEKDSLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKT 199 LP S C ++GWG ++G D L+ P++ ++C + ++ Sbjct: 127 SLPT--SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA--YPGQITSN 182 Query: 200 MVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAY 258 M CAG +G +C GDSGGP+ C S ++ GIVS+GS GC + KP VYT+V Y Sbjct: 183 MFCAGYLEGGKDSCQGDSGGPVVC-----SGKLQGIVSWGS--GCAQKNKPGVYTKVCNY 235 Query: 259 IDWINEKM 266 + WI + + Sbjct: 236 VSWIKQTI 243 >4J1Y-A nrPDB Length = 397 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 87/277 (31%), Positives = 128/277 (46%), Gaps = 33/277 (11%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C CGVP P AR +GG DA ++PWQ+ ++ W GG LI +V Sbjct: 127 LPKCVPVCGVPREPFEEKARAIGGSDADIKNFPWQVFF----DNPW---AGGALINEYWV 179 Query: 70 LTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL-------LRNDI 122 LTAAH + R + VG +++ S + + + +H W L NDI Sbjct: 180 LTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDI 239 Query: 123 ALIKLAEHVELSDTIQVACLPEKDS---LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQP 179 AL++L + V++ T+ CLP S L+ D ++GWGR A +L+ P Sbjct: 240 ALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDL-GLISGWGRTEKRD-RAVRLKAARLP 297 Query: 180 VVDHATCSRI-------DWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVF 232 V C + D + M+CAGG+ + +C GDSGG Q N + + Sbjct: 298 VAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFY 357 Query: 233 --GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 G+VS+G + C T +YTRV Y+DWI + MQ Sbjct: 358 AAGLVSWGPQ--CGTYG---LYTRVKNYVDWIMKTMQ 389 >1UTJ-A nrPDB Length = 242 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 130/239 (54%), Gaps = 20/239 (8%) Query: 29 RVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGK 88 ++VGG + +P+S P Q+SL ++ H CGG+L+ N+V++AAHC + R +G+ Sbjct: 20 KIVGGYECKPYSQPHQVSL-----NSGYHFCGGSLVNENWVVSAAHCYKSRVEVR--LGE 72 Query: 89 NNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSL 148 +N++V E F+ + H +++ + NDI LIKL++ L+ +Q LP S Sbjct: 73 HNIKVT-EGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPT--SC 129 Query: 149 LPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 P C V+GWG ++ ++KLQ P++ ++ C+ + + + M CAG +G Sbjct: 130 APAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCN--NSYPGMITNAMFCAGYLEG 187 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C NG E+ G+VS+G GC P VY +V + DW+ M Sbjct: 188 GKDSCQGDSGGPVVC---NG--ELQGVVSWG--YGCAEPGNPGVYAKVCIFNDWLTSTM 239 >2OLG-A nrPDB Length = 278 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/260 (29%), Positives = 128/260 (49%), Gaps = 25/260 (9%) Query: 29 RVVGGEDARPHSWPWQISLQYLKNDTWRH-TCGGTLIASNFVLTAAHCISNTRTYRVAVG 87 +++ G+D P +PW + Y + + CGG+LI + +++TAAHC++ R RV Sbjct: 22 KILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAG-RVLRVVGA 80 Query: 88 KNNLEVED-----------------EEGSLFVGVDTIHVHKRW--NALLLRNDIALIKLA 128 N + + + + + +G++ H + + +DIALI+L Sbjct: 81 LNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLN 140 Query: 129 EHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR 188 VE ++ I+ CLP+ + + V GWGR T G + Q+ PVV C++ Sbjct: 141 RQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTET-GQYSTIKQKLAVPVVHAEQCAK 199 Query: 189 -IDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRK 247 G RV+ + +CAGG+ +C GDSGGPL + N + + G+VSFG+ C T Sbjct: 200 TFGAAGVRVRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGAT--CGTEG 257 Query: 248 KPVVYTRVSAYIDWINEKMQ 267 P +YT+V Y DWI ++ Sbjct: 258 WPGIYTKVGKYRDWIEGNIR 277 >1ELV-A nrPDB Length = 333 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 86/277 (31%), Positives = 128/277 (46%), Gaps = 33/277 (11%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C CGVP P R++GG DA ++PWQ+ ++ W GG LI +V Sbjct: 63 LPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFF----DNPW---AGGALINEYWV 115 Query: 70 LTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL-------LRNDI 122 LTAAH + R + VG +++ S + + + +H W L NDI Sbjct: 116 LTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDI 175 Query: 123 ALIKLAEHVELSDTIQVACLPEKDS---LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQP 179 AL++L + V++ T+ CLP S L+ D ++GWGR A +L+ P Sbjct: 176 ALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDL-GLISGWGRTEKRD-RAVRLKAARLP 233 Query: 180 VVDHATCSRI-------DWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVF 232 V C + D + M+CAGG+ + +C GDSGG Q N + + Sbjct: 234 VAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFY 293 Query: 233 --GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 G+VS+G + C T +YTRV Y+DWI + MQ Sbjct: 294 AAGLVSWGPQ--CGTYG---LYTRVKNYVDWIMKTMQ 325 >2ZKS-A nrPDB Length = 240 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 84/239 (35%), Positives = 121/239 (50%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT-YRVAVGK 88 ++GG + PHS P+ SLQ +N + H CGG L+ +VLTAAHC++ R+ +G Sbjct: 1 IIGGREVIPHSRPYMASLQ--RNGS--HLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGL 56 Query: 89 NNLEVEDEEGSLFVGVDTIHVHKRWNAL-LLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + L D G F I H R+ + L ND+AL++L V+ S TI+ LP K Sbjct: 57 HTL---DSPGLTFHIKAAIQ-HPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQ 112 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 ++ C + GWG G ++ L++ V+D C+ +W + +MVC D Sbjct: 113 VVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADS 172 Query: 208 VISA-CNGDSGGPLNCQLENGSWEVF-GIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 A C GDSGGPL C G V G++SF SR C KP V T V+ Y+ WI + Sbjct: 173 KDQAPCKGDSGGPLVC----GKGRVLAGVLSFSSRV-CTDIFKPPVATAVAPYVSWIRK 226 >1A0J-A nrPDB Length = 223 Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 83/239 (34%), Positives = 130/239 (54%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + R +S +Q SLQ + H CGG+LI+S +V++AAHC + +V +G++ Sbjct: 1 IVGGYECRKNSASYQASLQ-----SGYHFCGGSLISSTWVVSAAHCYKS--RIQVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ V +E F+ + +H +N+ L NDI LIKL++ L+ + LP S Sbjct: 54 NIAV-NEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPS--SCA 110 Query: 150 PKDYPCYVTGWGRL-WTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 C V+GWG L ++ D L+ P++ ++C+ + ++ M CAG +G Sbjct: 111 SSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSA--YPGQITSNMFCAGFMEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C NG ++ G+VS+G GC R KP VYT+V Y WI+ M Sbjct: 169 GKDSCQGDSGGPVVC---NG--QLQGVVSWG--YGCAQRNKPGVYTKVCNYRSWISSTM 220 >1BDA-A nrPDB Length = 265 Score = 116 bits (291), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 85/277 (30%), Positives = 133/277 (48%), Gaps = 38/277 (13%) Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISL--QYLKNDTWRHTCGGTLIASNFVLTAA 73 +CG+ + R+ GG A S PWQ ++ ++ ++ R CGG LI+S ++L+AA Sbjct: 1 TCGLRQYS-QPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAA 59 Query: 74 HCISNT-----------RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDI 122 HC RTYRV G+ + E V+ VHK ++ NDI Sbjct: 60 HCFQERFPPHHLTVILGRTYRVVPGEEEQKFE---------VEKYIVHKEFDDDTYDNDI 110 Query: 123 ALIKLAEH----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGL 177 AL++L + S ++ CLP D LP C ++G+G+ P +++L++ Sbjct: 111 ALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAH 170 Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAGGD-------GVISACNGDSGGPLNCQLENGSWE 230 + + C+ V M+CAG + AC GDSGGPL C L +G Sbjct: 171 VRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVC-LNDGRMT 229 Query: 231 VFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + GI+S+G GC + P VYT+V+ Y+DWI + M+ Sbjct: 230 LVGIISWG--LGCGQKDVPGVYTKVTNYLDWIRDNMR 264 >4BXW-A nrPDB Length = 423 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 86/258 (33%), Positives = 129/258 (50%), Gaps = 25/258 (9%) Query: 24 PNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR 83 P+ R+V G D + PWQ +L K + CGGT+++ +VLTAAHCI+ T T Sbjct: 164 PSPDIRIVNGMDCKLGECPWQAALVDEKEGVF---CGGTILSPIYVLTAAHCINETETIS 220 Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHK---------RWNALLLRNDIALIKLAEHVELS 134 V VG+ ++ E + VD I+VHK +++ DIA+I++ ++ S Sbjct: 221 VVVGE--IDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFS 278 Query: 135 DTIQVACLPEKD----SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRID 190 + + ACLP D L+ +D+ V+G+GR+ GP + L+ P VD TC + Sbjct: 279 ENVVPACLPTADFANQVLMKQDFG-IVSGFGRIVEKGPKSKTLKVLKVPYVDRHTC--MV 335 Query: 191 WWGFRVKKTMVCAGGDGVI-SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKP 249 + M CAG D + AC GDSGGP + + + GIVS G GC K Sbjct: 336 SSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHF-ITGIVSSG--EGCARNGKY 392 Query: 250 VVYTRVSAYIDWINEKMQ 267 YT++S +I WI M+ Sbjct: 393 GNYTKLSKFIPWIKRIMR 410 >1FDP-A nrPDB Length = 235 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 125/248 (50%), Gaps = 16/248 (6%) Query: 21 SFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR 80 + PP R++GG +A H+ P+ S+Q H CGG L+A +VL+AAHC+ + Sbjct: 1 AAPPR--GRILGGREAEAHARPYMASVQL----NGAHLCGGVLVAEQWVLSAAHCLEDAA 54 Query: 81 TYRVAV--GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQ 138 +V V G ++L + L+ + + H + +D+ L++L+E L ++ Sbjct: 55 DGKVQVLLGAHSLSQPEPSKRLYDVLRAV-PHPDSQPDTIDHDLLLLQLSEKATLGPAVR 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKK 198 D + C V GWG + G D LQ L PV+D ATC+R + + Sbjct: 114 PLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITE 173 Query: 199 TMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAY 258 ++CA + S C GDSGGPL C G E G+V+ GSR C RKKP +YTRV++Y Sbjct: 174 RLMCAESNRRDS-CKGDSGGPLVC---GGVLE--GVVTSGSRV-CGNRKKPGIYTRVASY 226 Query: 259 IDWINEKM 266 WI+ + Sbjct: 227 AAWIDSVL 234 >4IGD-A nrPDB Length = 406 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 79/274 (28%), Positives = 132/274 (48%), Gaps = 28/274 (10%) Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 +L C CG+P F L A++ G A+ + PW L +L + CGG+L+ S++ Sbjct: 135 SLPTCLPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPF---CGGSLLGSSW 191 Query: 69 VLTAAHCISNT----------------RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKR 112 ++TAAHC+ + +++ +GK+ + +E +GV +H + Sbjct: 192 IVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQ 250 Query: 113 WNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADK 172 ++ ND+AL++L E L+ + CLPE + V+GWG+ + + Sbjct: 251 YDPNTFENDVALVELLESPVLNAFVMPICLPEGPQQ--EGAMVIVSGWGKQFLQR-FPET 307 Query: 173 LQQGLQPVVDHATCSR-IDWWGFRVKKTMVCAG-GDGVISACNGDSGGPL-NCQLENGSW 229 L + P+VDH+TC + +V + M+CAG +G AC GDSGGP+ E G W Sbjct: 308 LMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQW 367 Query: 230 EVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 + G VS+G C + + VY+ + DWI Sbjct: 368 YLVGTVSWGD--DCGKKDRYGVYSYIHHNKDWIQ 399 >5LHN-A nrPDB Length = 247 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 83/251 (33%), Positives = 130/251 (51%), Gaps = 19/251 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKN---DTWRHTCGGTLIASNFVLTAAHC---ISNTRTYR 83 +VGGE + PW ++ Y KN CGG+LI+ +V +AAHC + Y Sbjct: 1 IVGGEFTEVENQPWFAAI-YQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYV 59 Query: 84 VAVGKNNLEVEDEEGSLFVGVDTI--HVHKRWNALLLRNDIALIKL----AEHVELSDTI 137 V +G++ E G + V+ + H + R ++L NDIAL+K+ + + S +I Sbjct: 60 VYLGQSK-ESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSI 118 Query: 138 QVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADK-LQQGLQPVVDHATCSRIDWWGFRV 196 Q LP + + P C +TG+G+ + + K L+ + +V H C + ++G + Sbjct: 119 QTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEI 178 Query: 197 KKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 M+CA + +C GDSGGPL C +E G + GIVS+G RGC + KP VYTRV Sbjct: 179 NYKMLCAADPEWKTDSCKGDSGGPLICNIE-GRPTLSGIVSWG--RGCAEKNKPGVYTRV 235 Query: 256 SAYIDWINEKM 266 S ++DWI + Sbjct: 236 SHFLDWIQSHI 246 >2RDL-A nrPDB Length = 226 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 74/239 (30%), Positives = 119/239 (49%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + RPH+ P+ L+ + + C G LI NFV+TAAHC R+ V +G + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAG--RSITVLLGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N +V+++ + V+ H +++ L+ NDI L+KL E L+ + + K + + Sbjct: 59 NKKVKEDTWQK-LEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSI 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 P C GWGR N P +D LQ+ ++D C + + ++ +C G I Sbjct: 118 PPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFH---QEPQLCVGNPKKI 174 Query: 210 -SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + GDSGGPL C + GI S+ R K P V+TR+S Y WIN+ ++ Sbjct: 175 RNVYKGDSGGPLLC-----AGIAQGIASYVLRNA----KPPSVFTRISHYRPWINKILR 224 >1SC8-U nrPDB Length = 262 Score = 114 bits (284), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 133/259 (51%), Gaps = 18/259 (6%) Query: 17 CGVPSFPPNLSARVVGGEDARPHSWPWQISL-QYLKNDTWRHTCGGTLIASNFVLTAAHC 75 CG + P +++GGE + PW ++ + + + + CGG+LI+ +V++A HC Sbjct: 5 CGQKTLRPRF--KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHC 62 Query: 76 I---SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEH 130 Y V +G++ L + +G + V+ + +HK ++A L NDIAL+K+ Sbjct: 63 FIDYPKKEDYIVYLGRSRLN-SNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSK 121 Query: 131 ----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRL-WTNGPIADKLQQGLQPVVDHAT 185 + S TIQ LP + C +TG+G+ T+ ++L+ + ++ H Sbjct: 122 EGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRE 181 Query: 186 CSRIDWWGFRVKKTMVCAGGDG-VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCN 244 C + ++G V M+CA +C GDSGGPL C L+ G + GIVS+G RGC Sbjct: 182 CQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQ-GRMTLTGIVSWG--RGCA 238 Query: 245 TRKKPVVYTRVSAYIDWIN 263 + KP VYTRVS ++ WI Sbjct: 239 LKDKPGVYTRVSHFLPWIR 257 >3G01-A nrPDB Length = 227 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 72/239 (30%), Positives = 114/239 (47%), Gaps = 14/239 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + PHS P+ ++LK + CGG L+ FVLTAAHC R+ V +G + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC--KGRSMTVTLGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ + EE + V H +N NDI L+KL + + + ++ LP +++ + Sbjct: 59 NIKAK-EETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHV 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 CYV GWG++ +G L + V C + + +C G + Sbjct: 118 KPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCES-QFQSSYNRANEICVGDSKIK 176 Query: 210 SAC-NGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 A GDSGGPL C+ GIVS+G G P V+TRV +++ WI + M+ Sbjct: 177 GASFRGDSGGPLVCKRAAA-----GIVSYGQTDGS----APQVFTRVLSFVSWIKKTMK 226 >1FXY-A nrPDB Length = 228 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 120/239 (50%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + + PWQ L +N+ + CGGT+++ ++LTAAHC+ + ++V VG Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGF---CGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N E ++E G V+ + H R+ DIA+++L + + A LP Sbjct: 58 NTE-QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPAT 116 Query: 150 PKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 C ++GWG ++G D+LQ PV+ A C + ++ M C G +G Sbjct: 117 GTK--CLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS--YPGKITSNMFCVGFLEG 172 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C NG + G+VS+G GC + KP VYT+V Y+ WI + Sbjct: 173 GKDSCQGDSGGPVVC---NGQLQ--GVVSWGD--GCAQKNKPGVYTKVYNYVKWIKNTI 224 >3TK9-A nrPDB Length = 226 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 74/239 (30%), Positives = 121/239 (50%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ +Q+L+ + R CGG L+ +FVLTAAHC + + V +G + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKS-RKRCGGILVRKDFVLTAAHCQGS--SINVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E E F+ V H +N N+I L++L + + ++ LP + + Sbjct: 58 NIK-EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGV 208 C V GWG + + +A LQ+ L V C R+ + G + T +C G Sbjct: 117 KPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERL-FHGNYSRATEICVGDPKKT 174 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + GDSGGPL C+ GI+S+G+++G P VY +VS ++ WI M+ Sbjct: 175 QTGFKGDSGGPLVCK-----DVAQGILSYGNKKGT----PPGVYIKVSHFLPWIKRTMK 224 >2TLD-E nrPDB Length = 220 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 81/238 (34%), Positives = 125/238 (52%), Gaps = 22/238 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG ++ P+Q+SL ++ H CGG+LI S +V++AAHC + +V +G++ Sbjct: 1 IVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKS--GIQVRLGED 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ V E F+ VH +N+ L NDI LIKL L+ + LP S Sbjct: 54 NINVV-EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCA 110 Query: 150 PKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 C ++GWG ++G D L+ P++ ++C + ++ M CAG +G Sbjct: 111 SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA--YPGQITSNMFCAGLEGG 168 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S C GDSGGP+ C S ++ GIVS+GS GC + KP VYT+V Y+ WI + + Sbjct: 169 DS-CQGDSGGPVVC-----SGKLQGIVSWGS--GC-AKNKPGVYTKVCNYVSWIKQTI 217 >3QUM-P nrPDB Length = 237 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 129/250 (51%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS PWQ+ L R CGG L+ +VLTAAHCI N + +G++ Sbjct: 1 IVGGWECEKHSQPWQV----LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-----------DIALIKLAEHVELSDTIQ 138 +L ++ G +F V H ++ LL+N D+ L++L+E EL+D ++ Sbjct: 55 SLFHPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVK 197 V LP ++ L CY +GWG + + K Q + V+ + C+++ +V Sbjct: 114 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVT 169 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 K M+CAG G S C+GDSGGPL C NG + GI S+GS C ++P +YT+V Sbjct: 170 KFMLCAGRWTGGKSTCSGDSGGPLVC---NGVLQ--GITSWGSEP-CALPERPSLYTKVV 223 Query: 257 AYIDWINEKM 266 Y WI + + Sbjct: 224 HYRKWIKDTI 233 >2EEK-A nrPDB Length = 220 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 129/241 (53%), Gaps = 26/241 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS Q+SL ++ H CGG+L++ ++V++AAHC + RV +G++ Sbjct: 1 IVGGYECTKHSQAHQVSL-----NSGYHFCGGSLVSKDWVVSAAHCYKS--VLRVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK---D 146 ++ V +E ++ ++ H +++ + NDI LIKL + L+ + LP + D Sbjct: 54 HIRV-NEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAAD 112 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG- 205 + + C V+GWG ++ DKLQ P++ HA C+ + + + ++M CAG Sbjct: 113 ATM-----CTVSGWGNTMSSVADGDKLQCLSLPILSHADCA--NSYPGMITQSMFCAGYL 165 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 +G +C GDSGGP+ C NG + G+VS+G GC R P VY +V W+ + Sbjct: 166 EGGKDSCQGDSGGPVVC---NGVLQ--GVVSWG--YGCAERDHPGVYAKVCVLSGWVRDT 218 Query: 266 M 266 M Sbjct: 219 M 219 >4KKD-A nrPDB Length = 433 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 90/292 (30%), Positives = 142/292 (48%), Gaps = 34/292 (11%) Query: 9 ALLACASSCGVPSFP-PNLSARVVGGEDARPHSWPWQISL-----QYLKNDTWRHTCGGT 62 +L C CG PS P+L R++GG +A P +PWQ + + ND W + G Sbjct: 133 SLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGS--GA 190 Query: 63 LIASNFVLTAAHCISNTR--TYRVAVGKNNL-------EVEDEEGSLFVGVDTIHVHKRW 113 L++++++LTAAH + + R T + V K ++ +V D+ G++ + +H + Sbjct: 191 LLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDF 250 Query: 114 NALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPC-YVTGWG---------RL 163 N +DIAL++L E V L + CLP + P + V GWG + Sbjct: 251 NIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEI 310 Query: 164 WTNGP--IADKLQQGLQPVVDHATCS---RIDWWGFRVKKTMVCAGG-DGVISACNGDSG 217 ++G ++D LQ PVV HA C + V + M CAG +G C GDSG Sbjct: 311 ISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSG 370 Query: 218 GPLNCQLE-NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 + + W V G+VS+G C +++ VYT+VS Y+DW+ E+M L Sbjct: 371 EAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGL 422 >2HLC-A nrPDB Length = 230 Score = 110 bits (275), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 83/238 (34%), Positives = 122/238 (51%), Gaps = 15/238 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G +A +P+Q L D R CGG+LI + ++LTAAHC+ + + V +G Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGS- 59 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 EG V + I H +N ND+ALIK+ HVE +D IQ LP + L Sbjct: 60 ---AVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIP-HVEYTDNIQPIRLPSGEELN 115 Query: 150 PKDYPCY--VTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 K + V+GWG+ T+ I LQ V+D+ C++ G V+ T+ DG Sbjct: 116 NKFENIWATVSGWGQSNTDTVI---LQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDG 172 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 S C GDSGGP +N + G+VSF S GC + KPV ++RV++Y+DWI + Sbjct: 173 K-SPCFGDSGGPFVLSDKN---LLIGVVSFVSGAGCES-GKPVGFSRVTSYMDWIQQN 225 >1MKW-K nrPDB Length = 308 Score = 110 bits (274), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 92/270 (34%), Positives = 126/270 (46%), Gaps = 37/270 (13%) Query: 22 FPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----- 76 F + R+V G+DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 42 FESYIEGRIVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPW 99 Query: 77 ---SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVE 132 V +GK++ + + +D I++H R+N L DIAL+KL +E Sbjct: 100 DKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIE 159 Query: 133 LSDTIQVACLPEKDS---LLPKDYPCYVTGWG---RLWTNGPIADKLQQGLQ----PVVD 182 LSD I CLP+K + LL + VTGWG WT +A+ LQ P+V+ Sbjct: 160 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTS-VAEVQPSVLQVVNLPLVE 218 Query: 183 HATC---SRIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGI 234 C +RI R+ M CAG G+G AC GDSGGP + N W GI Sbjct: 219 RPVCKASTRI-----RITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGI 273 Query: 235 VSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 VS+G GC+ K YT V WI + Sbjct: 274 VSWGE--GCDRDGKYGFYTHVFRLKKWIQK 301 >3F6U-H nrPDB Length = 240 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 123/245 (50%), Gaps = 21/245 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G+ R PWQ+ L K + CG LI ++VLTAAHC+ ++ V +G+ Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKK---KLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEY 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE----K 145 +L E+ L + + + VH ++ NDIAL+ LA+ LS TI CLP+ + Sbjct: 58 DLR-RWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAE 116 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-----PVVDHATCSRIDWWGFRVKKTM 200 L VTGWG + A + + + PVV H CS + V + M Sbjct: 117 RELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEV--MSNMVSENM 174 Query: 201 VCAG--GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAY 258 +CAG GD AC GDSGGP+ +G+W + G+VS+G GC VYT+VS Y Sbjct: 175 LCAGILGDRQ-DACEGDSGGPMVASF-HGTWFLVGLVSWG--EGCGLLHNYGVYTKVSRY 230 Query: 259 IDWIN 263 +DWI+ Sbjct: 231 LDWIH 235 >1PPF-E nrPDB Length = 218 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 87/240 (36%), Positives = 120/240 (50%), Gaps = 24/240 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC--ISNTRTYRVAVG 87 +VGG ARPH+WP+ +SLQ H CG TLIA NFV++AAHC N R RV +G Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +NL + +F V I ++ + L NDI +++L ++ +QVA LP + Sbjct: 57 AHNLSRREPTRQVFA-VQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 114 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 L C GWG L N IA LQ+ L V + C R + T+V G Sbjct: 115 RLGNGVQCLAMGWGLLGRNRGIASVLQE-LNVTVVTSLCRRSNVC------TLVRGRQAG 167 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 V C GDSG PL C NG + GI SF R GC + P + V+ +++WI+ +Q Sbjct: 168 V---CFGDSGSPLVC---NG--LIHGIASF-VRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >5UBM-A nrPDB Length = 252 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 121/258 (46%), Gaps = 33/258 (12%) Query: 29 RVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGK 88 R++GG DA ++PWQ+ ++ W GG LI +VLTAAH + R + VG Sbjct: 1 RIIGGSDADIKNFPWQVFF----DNPW---AGGALINEYWVLTAAHVVEGNREPTMYVGS 53 Query: 89 NNLEVEDEEGSLFVGVDTIHVHKRWNALL-------LRNDIALIKLAEHVELSDTIQVAC 141 +++ S + + + +H W L NDIAL++L + V++ T+ C Sbjct: 54 TSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 142 LPEKDS---LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRI-------DW 191 LP S L+ D ++GWGR A +L+ PV C + D Sbjct: 114 LPGTSSDYNLMDGDL-GLISGWGRTEKRD-RAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 192 WGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVF--GIVSFGSRRGCNTRKKP 249 + M+CAGG+ + +C GDSGG Q N + + G+VS+G + C T Sbjct: 172 EAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ--CGTYG-- 227 Query: 250 VVYTRVSAYIDWINEKMQ 267 +YTRV Y+DWI + MQ Sbjct: 228 -LYTRVKNYVDWIMKTMQ 244 >5C67-A nrPDB Length = 224 Score = 107 bits (267), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 128/239 (53%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +S P+Q+SL ++ H CGG+LI+ +V++AAHC TR +V +G++ Sbjct: 1 IVGGYTCEENSLPYQVSL-----NSGSHFCGGSLISEQWVVSAAHCYK-TRI-QVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++V E F+ I H ++N L NDI LIKL+ ++ + LP Sbjct: 54 NIKVL-EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 112 Query: 150 PKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 + C ++GWG + G D+L+ PV+ A C + + G ++ +M C G +G Sbjct: 113 GTE--CLISGWGNTLSFGADYPDELKCLDAPVLTQAEC-KASYPG-KITNSMFCVGFLEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C D+GGP+ C NG + G+VS+G GC + +P VYT+V Y+DWI + + Sbjct: 169 GKDSCQRDAGGPVVC---NGQLQ--GVVSWG--HGCAWKNRPGVYTKVYNYVDWIKDTI 220 >4WWY-A nrPDB Length = 224 Score = 107 bits (266), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 77/239 (32%), Positives = 121/239 (50%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + +S P+Q+SL ++ H CGG+LI +V++A HC + +V +G++ Sbjct: 1 IVGGYNCEENSVPYQVSL-----NSGYHFCGGSLINEQWVVSAGHCYKSR--IQVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+EV E F+ I H +++ L NDI LIKL+ ++ + LP Sbjct: 54 NIEVL-EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPAT 112 Query: 150 PKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 C ++GWG ++G D+LQ PV+ A C + ++ M C G +G Sbjct: 113 GTK--CLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS--YPGKITSNMFCVGFLEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C DSGGP+ C NG + G+VS+G GC + KP VYT+V Y+ WI + Sbjct: 169 GKDSCQRDSGGPVVC---NGQLQ--GVVSWGD--GCAQKNKPGVYTKVYNYVKWIKNTI 220 >1ETT-H nrPDB Length = 259 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 90/262 (34%), Positives = 123/262 (46%), Gaps = 37/262 (14%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G+DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + + +D I++H R+N L DIAL+KL +ELSD I Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 141 CLPEKDS---LLPKDYPCYVTGWG---RLWTNGPIADKLQQGLQ----PVVDHATC---S 187 CLP+K + LL + VTGWG WT +A+ LQ P+V+ C + Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTS-VAEVQPSVLQVVNLPLVERPVCKAST 177 Query: 188 RIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRG 242 RI R+ M CAG G+G AC GDSGGP + N W GIVS+G G Sbjct: 178 RI-----RITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE--G 230 Query: 243 CNTRKKPVVYTRVSAYIDWINE 264 C+ K YT V WI + Sbjct: 231 CDRDGKYGFYTHVFRLKKWIQK 252 >4XDE-A nrPDB Length = 257 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 112/230 (48%), Gaps = 16/230 (6%) Query: 49 YLKNDTWRHT-CGGTLIASNFVLTAAHCISN---TRTYRVAVGKNNLEVEDEEGSLFVGV 104 Y+ W H+ C G+LIA +VLTAAHC+ + V +G+ E + V Sbjct: 16 YIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRN-HSCEPCQTLAV 74 Query: 105 DTIHVHKRWNALLLRNDIALIKLAEHVE-----LSDTIQVACLPEKDSLLPKDYPCYVTG 159 + +H+ ++ + ++D+AL++L E + LS +Q LP + + C V G Sbjct: 75 RSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGAARPSETTLCQVAG 134 Query: 160 WGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSG 217 WG + A LQ+ P + CS D G + M+CAG +G AC GDSG Sbjct: 135 WGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSG 194 Query: 218 GPLNC--QLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 GPL C Q + GI+S+GS GC R KP VYT V+ Y+ WI E Sbjct: 195 GPLVCEDQAAERRLTLQGIISWGS--GCGDRNKPGVYTDVAYYLAWIREH 242 >4NFE-A nrPDB Length = 237 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 129/250 (51%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS PWQ+++ + W H CGG L+ +VLTAAHC+ + +V +G++ Sbjct: 1 IVGGWECEKHSQPWQVAVY---SHGWAH-CGGVLVHPQWVLTAAHCLK--KNSQVWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQ 138 NL E E+ V V H +N LL+ +D+ L++L+E +++D ++ Sbjct: 55 NL-FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVK 197 V LP ++ L CY +GWG + + + Q + ++ + C+R + +V Sbjct: 114 VLGLPTQEPALGTT--CYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVT 169 Query: 198 KTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + M+CAG G C GDSGGPL C NG + GI S+G C +KP VYT+V Sbjct: 170 EFMLCAGLWTGGKDTCGGDSGGPLVC---NGVLQ--GITSWGPEP-CALPEKPAVYTKVV 223 Query: 257 AYIDWINEKM 266 Y WI + + Sbjct: 224 HYRKWIKDTI 233 >1ORF-A nrPDB Length = 234 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 120/238 (50%), Gaps = 17/238 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + PHS P+ + L + + C G LIA ++VLTAAHC N R+ +V +G + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKRS-QVILGAH 55 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 ++ E+ + + V + ++ D+ L++L E +++ + + LP+K + Sbjct: 56 SITREEPTKQIML-VKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDV 114 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFR--VKKTMVCAGG-D 206 C V GWGR + +D L++ ++D C+ + + F + MVCAG Sbjct: 115 KPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 174 Query: 207 GVISACNGDSGGPLNCQLENGSWEVF-GIVSFGSRRGCNTRKKPVVYTRVS-AYIDWI 262 G +CNGDSG PL C+ VF G+ SFG C + P VY +S +++WI Sbjct: 175 GGRDSCNGDSGSPLLCE------GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 226 >3NXP-A nrPDB Length = 424 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 89/266 (33%), Positives = 119/266 (44%), Gaps = 37/266 (13%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------S 77 + R+V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 162 IDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 219 Query: 78 NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDT 136 V +GK++ + ++ I++H R+N L DIAL+KL + V SD Sbjct: 220 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 279 Query: 137 IQVACLPEKD---SLLPKDYPCYVTGWGRL---WTNGPIADK---LQQGLQPVVDHATCS 187 I CLP+++ SLL Y VTGWG L WT + LQ P+V+ C Sbjct: 280 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 339 Query: 188 RIDWWGFRVKKTMVCAG--------GDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFG 238 D R+ M CAG GD AC GDSGGP + N W GIVS+G Sbjct: 340 --DSTRIRITDNMFCAGYKPDEGKRGD----ACEGDSGGPFVMKSPFNNRWYQMGIVSWG 393 Query: 239 SRRGCNTRKKPVVYTRVSAYIDWINE 264 GC+ K YT V WI + Sbjct: 394 E--GCDRDGKYGFYTHVFRLKKWIQK 417 >3K65-B nrPDB Length = 308 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 88/266 (33%), Positives = 119/266 (44%), Gaps = 37/266 (13%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------S 77 + R+V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 46 IDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 103 Query: 78 NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDT 136 V +GK++ + ++ I++H R+N L DIAL+KL + V SD Sbjct: 104 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 163 Query: 137 IQVACLPEKD---SLLPKDYPCYVTGWGRL---WTNGPIADK---LQQGLQPVVDHATCS 187 I CLP+++ SLL Y VTGWG L WT + LQ P+V+ C Sbjct: 164 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 223 Query: 188 RIDWWGFRVKKTMVCAG--------GDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFG 238 D R+ M CAG GD AC GD+GGP + N W GIVS+G Sbjct: 224 --DSTRIRITDNMFCAGYKPDEGKRGD----ACEGDAGGPFVMKSPFNNRWYQMGIVSWG 277 Query: 239 SRRGCNTRKKPVVYTRVSAYIDWINE 264 GC+ K YT V WI + Sbjct: 278 E--GCDRDGKYGFYTHVFRLKKWIQK 301 >2JET-B nrPDB Length = 128 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 53/130 (40%), Positives = 74/130 (56%), Gaps = 5/130 (3%) Query: 33 GEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLE 92 GEDA P SWPWQ+SLQ + T H CGG+LI+ ++V+TAAHC +T V V + Sbjct: 1 GEDAIPGSWPWQVSLQ---DKTGFHFCGGSLISEDWVVTAAHC--GVKTSDVVVAGEFDQ 55 Query: 93 VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKD 152 DEE + + + + ++N +RNDI L+KLA + S+T+ CLP D P Sbjct: 56 GSDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPG 115 Query: 153 YPCYVTGWGR 162 C TGWG+ Sbjct: 116 TVCATTGWGK 125 >2OCV-B nrPDB Length = 259 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 93/265 (35%), Positives = 119/265 (44%), Gaps = 43/265 (16%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHCI Sbjct: 1 IVEGWDAEKGIAPWQVML--FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + ++ I+VH R+N L DIAL+KL + V SD I Sbjct: 59 LLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPV 118 Query: 141 CLPEKD---SLLPKDYPCYVTGWGRL---WT---NGPIADKLQQGLQPVVDHATC---SR 188 CLP+K SLL Y VTGWG L WT N LQ P+V+ C +R Sbjct: 119 CLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTR 178 Query: 189 IDWWGFRVKKTMVCAG--------GDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFGS 239 I R+ M CAG GD AC GDSGGP + N W GIVS+G Sbjct: 179 I-----RITDNMFCAGFKVNDTKRGD----ACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 229 Query: 240 RRGCNTRKKPVVYTRVSAYIDWINE 264 GC+ + K YT V WI + Sbjct: 230 --GCDRKGKYGFYTHVFRLKAWIQK 252 >4NZQ-A nrPDB Length = 557 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 89/266 (33%), Positives = 119/266 (44%), Gaps = 37/266 (13%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------S 77 + R+V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 295 IDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 352 Query: 78 NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDT 136 V +GK++ + ++ I++H R+N L DIAL+KL + V SD Sbjct: 353 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 412 Query: 137 IQVACLPEKD---SLLPKDYPCYVTGWGRL---WTNGPIADK---LQQGLQPVVDHATCS 187 I CLP+++ SLL Y VTGWG L WT + LQ P+V+ C Sbjct: 413 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 472 Query: 188 RIDWWGFRVKKTMVCAG--------GDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFG 238 D R+ M CAG GD AC GDSGGP + N W GIVS+G Sbjct: 473 --DSTRIRITDNMFCAGYKPDEGKRGD----ACEGDSGGPFVMKSPFNNRWYQMGIVSWG 526 Query: 239 SRRGCNTRKKPVVYTRVSAYIDWINE 264 GC+ K YT V WI + Sbjct: 527 E--GCDRDGKYGFYTHVFRLKKWIQK 550 >4Z6A-H nrPDB Length = 249 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 83/246 (33%), Positives = 126/246 (51%), Gaps = 19/246 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR---VAV 86 +VGG+ PWQ+ L L N CGGTLI + +V++AAHC + +R + Sbjct: 1 IVGGKVCPKGECPWQVLL--LVNGA--QLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVL 56 Query: 87 GKNNLEVED-EEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 G+++L D +E S V + + + +DIAL++L + V L+D + CLPE+ Sbjct: 57 GEHDLSEHDGDEQSRRVA--QVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPER 114 Query: 146 ---DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 + L V+GWG+L G A +L P + C + ++ + M C Sbjct: 115 TFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEAS--YPGKITEYMFC 172 Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG DG +C GDSGGP + G+W + GIVS+G +GC T VYTRVS YI+W Sbjct: 173 AGYSDGSKDSCKGDSGGP-HATHYRGTWYLTGIVSWG--QGCATVGHFGVYTRVSQYIEW 229 Query: 262 INEKMQ 267 + + M+ Sbjct: 230 LQKLMR 235 >1KYN-A nrPDB Length = 235 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 75/239 (31%), Positives = 114/239 (47%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG ++RPHS P+ LQ +++ + CGG L+ +FVLTAAHC + V +G + Sbjct: 1 IIGGRESRPHSRPYMAYLQ-IQSPAGQSRCGGFLVREDFVLTAAHCWGSN--INVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ + I H ++N ++NDI L++L+ V + + LP L Sbjct: 58 NIQRRENTQQHITARRAIR-HPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 C V GWGR+ D L++ V C RI +G + +C G Sbjct: 117 RPGTLCTVAGWGRVSMRRG-TDTLREVQLRVQRDRQCLRI--FGSYDPRRQICVGDRRER 173 Query: 210 SAC-NGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 A GDSGGPL C + GIVS+G G P V+TRVS+++ WI M+ Sbjct: 174 KAAFKGDSGGPLLC-----NNVAHGIVSYGKSSGV----PPEVFTRVSSFLPWIRTTMR 223 >4IW4-E nrPDB Length = 279 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 84/272 (30%), Positives = 134/272 (49%), Gaps = 37/272 (13%) Query: 30 VVGGEDARPHSWPWQISL-----QYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR--TY 82 ++GG +A P +PWQ + + ND W + G L++++++LTAAH + + R T Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGS--GALLSASWILTAAHVLRSQRRDTT 58 Query: 83 RVAVGKNNL-------EVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSD 135 + V K ++ +V D+ G++ + +H +N +DIAL++L E V L Sbjct: 59 VIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 118 Query: 136 TIQVACLPEKDSLLPKDYPC-YVTGWG---------RLWTNGP--IADKLQQGLQPVVDH 183 + CLP + P + V GWG + ++G ++D LQ PVV H Sbjct: 119 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 178 Query: 184 ATC-----SRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLE-NGSWEVFGIVS 236 A C SR + V + M CAG +G C GDSGG + + W V G+VS Sbjct: 179 AECKTSYESRSG--NYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVS 236 Query: 237 FGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 +G C +++ VYT+VS Y+DW+ E+M L Sbjct: 237 WGGPEECGSKQVYGVYTKVSNYVDWVWEQMGL 268 >1VR1-H nrPDB Length = 261 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 88/262 (33%), Positives = 120/262 (45%), Gaps = 33/262 (12%) Query: 30 VVGGEDARPHSWPWQISL--QYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNT 79 +V G DA PWQ+ L ++ ++ R CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 80 RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQ 138 V +GK++ + ++ I++H R+N L DIAL+KL + V SD I Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 139 VACLPEKD---SLLPKDYPCYVTGWGRL---WTNGPIADK---LQQGLQPVVDHATCSRI 189 CLP+++ SLL Y VTGWG L WT + LQ P+V+ C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK-- 178 Query: 190 DWWGFRVKKTMVCA------GGDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRG 242 D R+ M CA G G AC GDSGGP + N W GIVS+G G Sbjct: 179 DSTRIRITDNMFCAYYKPDEGKRG--DACEGDSGGPFVMKSPFNNRWYQMGIVSWGE--G 234 Query: 243 CNTRKKPVVYTRVSAYIDWINE 264 C+ K YT V WI + Sbjct: 235 CDRDGKYGFYTHVFRLKKWIQK 256 >4Q7Y-A nrPDB Length = 250 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 74/238 (31%), Positives = 117/238 (49%), Gaps = 18/238 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS--NTRTYRVAVG 87 ++GG + PHS P+ S+++ +H CGG L+ + +V++AAHC S + RT V +G Sbjct: 1 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + L + +F G+D + H ++ + NDI L++L L + + LP + + Sbjct: 57 AHVLSTAEPTQQVF-GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRA 115 Query: 148 LLP-KDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC--AG 204 P C V GWG + + L + V+D C+ W + TM+C +G Sbjct: 116 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRSG 173 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 C+ DSGGPL C+ G+VSF S C K P VYT+VSA++ WI Sbjct: 174 DSHRRGFCSADSGGPLVCRN-----RAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWI 225 >1IAU-A nrPDB Length = 227 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 72/239 (30%), Positives = 112/239 (46%), Gaps = 15/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ L + + CGG LI +FVLTAAHC ++ V +G + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSS--INVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E E F+ V H +N NDI L++L + + +Q LP + + Sbjct: 58 NIK-EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 208 C V GWG+ G + LQ+ V + C D + +C G + Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIELCVGDPEIK 175 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 ++ GDSGGPL C + GIVS+G G P T+VS+++ WI + M+ Sbjct: 176 KTSFKGDSGGPLVC-----NKVAQGIVSYGRNNGM----PPRACTKVSSFVHWIKKTMK 225 >1SPJ-A nrPDB Length = 238 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 81/251 (32%), Positives = 124/251 (49%), Gaps = 31/251 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS PWQ +L + CGG L+ +VLTAAHCIS+ Y++ +G++ Sbjct: 1 IVGGWECEQHSQPWQAALYHFST----FQCGGILVHRQWVLTAAHCISD--NYQLWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-----------DIALIKLAEHVE-LSDTI 137 NL +DE + FV V H +N LL N D+ L++L E + ++D + Sbjct: 55 NL-FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAV 113 Query: 138 QVACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 +V LP ++ + C +GWG + N D LQ ++ + C + +V Sbjct: 114 KVVELPTEEPEVGST--CLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQ--KV 169 Query: 197 KKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 M+C G +G C GDSGGPL C +G + G+ S+G C T KP V RV Sbjct: 170 TDFMLCVGHLEGGKDTCVGDSGGPLMC---DGVLQ--GVTSWG-YVPCGTPNKPSVAVRV 223 Query: 256 SAYIDWINEKM 266 +Y+ WI + + Sbjct: 224 LSYVKWIEDTI 234 >5FCR-A nrPDB Length = 234 Score = 100 bits (249), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 119/236 (50%), Gaps = 15/236 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTYRVAV 86 ++GG++A H+ P+ S+Q N T H CGGTL+ +VL+AAHC +++ + +V + Sbjct: 1 ILGGQEAAAHARPYMASVQV--NGT--HVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G ++L E + V ++ H L +D+ L KL+++ L ++ L +D Sbjct: 57 GAHSLSAP-EPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYED 115 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 + C V GWG + G D L Q +++ TC+ + V M+CA + Sbjct: 116 KEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESN 175 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 C GDSG PL C V G+V++GSR C KKP VYTRVS+Y WI Sbjct: 176 -RRDTCRGDSGSPLVC-----GDAVEGVVTWGSRV-CGNGKKPGVYTRVSSYRMWI 224 >4DJZ-B nrPDB Length = 251 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 71/253 (28%), Positives = 121/253 (47%), Gaps = 28/253 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT---------- 79 + G A+ + PW L +L + CGG+L+ S++++TAAHC+ + Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPF---CGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 80 ------RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVEL 133 +++ +GK+ + +E +GV +H +++ ND+AL++L E L Sbjct: 58 SDLLSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVL 116 Query: 134 SDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR-IDWW 192 + + CLPE + V+GWG+ + + L + P+VDH+TC + Sbjct: 117 NAFVMPICLPEGPQQ--EGAMVIVSGWGKQFLQR-FPETLMEIEIPIVDHSTCQKAYAPL 173 Query: 193 GFRVKKTMVCAG-GDGVISACNGDSGGPL-NCQLENGSWEVFGIVSFGSRRGCNTRKKPV 250 +V + M+CAG +G AC GDSGGP+ E G W + G VS+G C + + Sbjct: 174 KKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD--DCGKKDRYG 231 Query: 251 VYTRVSAYIDWIN 263 VY+ + DWI Sbjct: 232 VYSYIHHNKDWIQ 244 >5KWM-A nrPDB Length = 230 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 75/238 (31%), Positives = 113/238 (47%), Gaps = 17/238 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGGEDA P+ ++L + CGGTL A N V+TAAHC ++ + V Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQF---CGGTLAAPNKVVTAAHCTVGSQPADINVVSG 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + EG++ V + VH + D++++ L V+ + I++A D+ Sbjct: 58 RTVMSSNEGTVSK-VTNVWVHPEYQDAAKGFDVSVLTLEAPVKEA-PIELA--KADDAGY 113 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGV 208 D + GWG G AD LQ+ PV TC + +G MVCAG +G Sbjct: 114 APDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQA--YGEYTPDAMVCAGVPEGG 171 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + C GDSGGP+ + ++ G+ S+G GC KP VY RV AY D + E++ Sbjct: 172 VDTCQGDSGGPMVV-----NNKLIGVTSWG--EGCARPGKPGVYARVGAYYDVLMEQI 222 >1SGF-G nrPDB Length = 237 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 123/250 (49%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +S PW +++ ++ CGG L+ N+VLTAAHC + Y+V +GKN Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYT----QYLCGGVLLDPNWVLTAAHCYDD--NYKVWLGKN 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQ 138 NL +DE + V H +N L+R ND+ L++L++ +++DT++ Sbjct: 55 NL-FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVK 197 LP ++ L C +GWG + T D L ++ + C++ +V Sbjct: 114 PITLPTEEPKLGST--CLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIE--KVT 169 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 M+CAG DG C GDSGGPL C +G + GI S+G C P VYT+++ Sbjct: 170 DAMLCAGEMDGGKDTCKGDSGGPLIC---DGVLQ--GITSWG-HTPCGEPDMPGVYTKLN 223 Query: 257 AYIDWINEKM 266 + WI + M Sbjct: 224 KFTSWIKDTM 233 >5TO3-B nrPDB Length = 409 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 88/262 (33%), Positives = 117/262 (44%), Gaps = 37/262 (14%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + ++ I++H R+N L DIAL+KL + V SD I Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 141 CLPEKD---SLLPKDYPCYVTGWGRL---WTNGPIADK---LQQGLQPVVDHATCSRIDW 191 CLP+++ SLL Y VTGWG L WT + LQ P+V+ C D Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK--DS 176 Query: 192 WGFRVKKTMVCAG--------GDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRG 242 R+ M CAG GD AC GDSGGP + N W GIVS G+ G Sbjct: 177 TRIRITDNMFCAGYKPDEGKRGD----ACEGDSGGPFVMKSPFNNRWYQMGIVSAGA--G 230 Query: 243 CNTRKKPVVYTRVSAYIDWINE 264 C+ K YT V WI + Sbjct: 231 CDRDGKYGFYTHVFRLKKWIQK 252 >5MS3-A nrPDB Length = 228 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 114/239 (47%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG + +PHS PWQ +L + + CGG L+ N+VLTAAHC Y V +G + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQ----QLLCGGVLVGGNWVLTAAHC--KKPKYTVRLGDH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN---DIALIKLAEHVELSDTIQVACLPEKD 146 +L+ +D V +I H +N+ + + D+ L++L + L ++ L D Sbjct: 55 SLQNKDGPEQEIPVVQSI-PHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL--AD 111 Query: 147 SLLPKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 C V+GWG + + D L + C D + ++ MVCAG Sbjct: 112 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCE--DAYPGQITDGMVCAGS 169 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 C GDSGGPL C +G+ + GI S+GS C KP VYT + Y+DWI + Sbjct: 170 SKGADTCQGDSGGPLVC---DGALQ--GITSWGSDP-CGRSDKPGVYTNICRYLDWIKK 222 >1NPM-A nrPDB Length = 225 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 112/241 (46%), Gaps = 21/241 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G + PHS PWQ +L + R CGG L+ +VLTAAHC + Y V +G + Sbjct: 1 ILEGRECIPHSQPWQAALFQGE----RLICGGVLVGDRWVLTAAHC--KKQKYSVRLGDH 54 Query: 90 NLEVEDE-EGSLFVGVDTIH-VHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +L+ D+ E + V H + N +DI LI+L L D ++ L + Sbjct: 55 SLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLA---N 111 Query: 148 LLPK-DYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 L PK C ++GWG + + + L + C R + ++ + MVCAG Sbjct: 112 LCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERA--YPGKITEGMVCAGS 169 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 C GDSGGPL C + GI S+GS C +KP VYT++ Y WI + Sbjct: 170 SNGADTCQGDSGGPLVC-----DGMLQGITSWGSDP-CGKPEKPGVYTKICRYTTWIKKT 223 Query: 266 M 266 M Sbjct: 224 M 224 >6BQM-A nrPDB Length = 506 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 122/251 (48%), Gaps = 17/251 (6%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVA 85 +S+R++GGE A WP+ ++L ++ CGG+ + +VLTAAHC+ + Sbjct: 7 VSSRIIGGEQATAGEWPYMVALT--ARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGD 64 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 V ++ D + + V I+VH + + NDIA+++L ++Q++ + Sbjct: 65 VLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDF 124 Query: 146 DSLLPKDYPCYVTGWG-RLWTNGPIADK---LQQGLQPVVDHATC----SRIDWWG--FR 195 + L KD P V G+G R +G +D L Q P V C S D + Sbjct: 125 NELT-KDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 196 VKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 + CAG G AC+GD+GGP+ NG ++ G+VS+G GC P VYT + Sbjct: 184 LTNNAFCAGSFGK-DACSGDAGGPIFFDSNNGRKQM-GVVSWGD--GCGRANSPGVYTNL 239 Query: 256 SAYIDWINEKM 266 S + DW++++ Sbjct: 240 SVFNDWLDDQQ 250 >1YM0-A nrPDB Length = 238 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 70/244 (28%), Positives = 126/244 (51%), Gaps = 16/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVA--VG 87 +VGG +ARP+ +PWQ+S++ +D+ H CGG++I +V+ AAHC+ V+ VG Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDS--HFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE-KD 146 +++ VD+I V++ ++ L ND+++IK A + + C P+ + Sbjct: 59 EHDSSAASTVRQTH-DVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAN 117 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADK-LQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 + + C +GWG + + G L+ + +A C + + + M+CA Sbjct: 118 DYVYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAV-YTSDTIYDDMICATD 174 Query: 206 DGVIS---ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 + ++ +C GDSGGPL+ + +G + + GIVS+G GC P VY+RV + WI Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWG--IGC-ASGYPGVYSRVGFHAGWI 231 Query: 263 NEKM 266 + + Sbjct: 232 TDTI 235 >2B9L-A nrPDB Length = 394 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 122/253 (48%), Gaps = 25/253 (9%) Query: 35 DARPHSWPWQISLQYLKNDTW------RHTCGGTLIASNFVLTAAHCI----SNTRTYRV 84 +A +PW +++ LK + + CGG+LIA + VLT AHC+ SN ++ Sbjct: 136 EAEYGEFPWMVAV--LKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKI 193 Query: 85 AVGK-NNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP 143 G+ + L ++ + + +H +N + ND+AL+ L + +D I CLP Sbjct: 194 RAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLP 253 Query: 144 EKDSLLPKDYPCYVTGWGR--LWTNGPIADKLQQGLQPVVDHATCS---RIDWWG--FRV 196 ++ + C+ +GWG+ + ++ L++ P VD C R G F + Sbjct: 254 QQSQIF-DSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVL 312 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNC-QLENGS-WEVFGIVSFGSRRGCNTRKKPVVYTR 254 +T VCAGG+ C GD G PL C N S + GIV++G GC P VY Sbjct: 313 DQTFVCAGGEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI--GCGDENVPGVYAN 370 Query: 255 VSAYIDWINEKMQ 267 V+ + +WI+++MQ Sbjct: 371 VAHFRNWIDQEMQ 383 >1AO5-A nrPDB Length = 237 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 78/251 (31%), Positives = 121/251 (48%), Gaps = 32/251 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG + +S PWQ+++ Y K H CGG L+ N+VLTAAHC + Y V +GKN Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKN 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLL-----------RNDIALIKLAEHVELSDTIQ 138 L ++E + V H +N LL +D+ L++L++ +++D ++ Sbjct: 55 KL-FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVK 113 Query: 139 VACLPEKDSLLPKD-YPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 LP K+ PK C +GWG + T D LQ ++ + C+++ + +V Sbjct: 114 PIALPTKE---PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV--YLQKV 168 Query: 197 KKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 M+CAG G C DSGGPL C +G + G S+G C P +YT + Sbjct: 169 TDVMLCAGEMGGGKDTCRDDSGGPLIC---DGILQ--GTTSYGPVP-CGKPGVPAIYTNL 222 Query: 256 SAYIDWINEKM 266 + WI + M Sbjct: 223 IKFNSWIKDTM 233 >1SGF-A nrPDB Length = 240 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 77/244 (31%), Positives = 117/244 (47%), Gaps = 36/244 (14%) Query: 39 HSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEG 98 +S PW +++ ++ CGG L+ N+VLTAAHC ++ Y+V +GKNN +EDE Sbjct: 13 NSQPWHVAVYRFN----KYQCGGVLLDRNWVLTAAHCYND--KYQVWLGKNNF-LEDEPS 65 Query: 99 SLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQVACLPEKDS 147 V H +N LL ND+ L++L++ +++D ++ LP ++ Sbjct: 66 DQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEP 125 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV----VDHATCSRIDWWGFRVKKTMVCA 203 L C +GWG + PI K LQ V + + C + +V M+CA Sbjct: 126 KLGST--CLASGWG---STTPIKFKYPDDLQCVNLKLLPNEDCDKAH--EMKVTDAMLCA 178 Query: 204 GG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 G DG C DSGGPL C +G + GI S+G C +P VYT++ + WI Sbjct: 179 GEMDGGSYTCEHDSGGPLIC---DGILQ--GITSWGPEP-CGEPTEPSVYTKLIKFSSWI 232 Query: 263 NEKM 266 E M Sbjct: 233 RETM 236 >2ASU-B nrPDB Length = 234 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 81/245 (33%), Positives = 120/245 (48%), Gaps = 24/245 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT----YRVA 85 VVGG P + PW +SL +N +H CGG+L+ ++LTA C S+ Y V Sbjct: 1 VVGGH---PGNSPWTVSL---RNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVW 54 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 +G + E SL + V K + + L+KL V L+ + + CLP + Sbjct: 55 LGTLFQNPQHGEPSL----QRVPVAKMVCGPS-GSQLVLLKLERSVTLNQRVALICLPPE 109 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADK-LQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG 204 ++P C + GWG T G D L L V+ + C+ I G RV+++ +C Sbjct: 110 WYVVPPGTKCEIAGWGE--TKGTGNDTVLNVALLNVISNQECN-IKHRG-RVRESEMCTE 165 Query: 205 G-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 G + AC GD GGPL C N SW + GI+ R C + P V+TRVS ++DWI+ Sbjct: 166 GLLAPVGACEGDYGGPLACFTHN-SWVLEGIII--PNRVCARSRWPAVFTRVSVFVDWIH 222 Query: 264 EKMQL 268 + M+L Sbjct: 223 KVMRL 227 >2PSX-A nrPDB Length = 227 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 113/241 (46%), Gaps = 20/241 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G D H+ PWQ +L N + CG L+ ++LTAAHC + +RV +G Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLY---CGAVLVHPQWLLTAAHC--RKKVFRVRLGHY 55 Query: 90 NLEVEDEEGS-LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSL 148 +L E G +F GV +I H ++ ND+ LIKL + + ++ S Sbjct: 56 SLSPVYESGQQMFQGVKSI-PHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPI---NVSSH 111 Query: 149 LPK-DYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVKKTMVCAGGD 206 P C V+GWG + K+ Q L V+ C D + ++ TM CAG Sbjct: 112 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCE--DAYPRQIDDTMFCAGDK 169 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C NGS + G+VS+G C +P VYT + + WI E + Sbjct: 170 AGRDSCQGDSGGPVVC---NGSLQ--GLVSWGD-YPCARPNRPGVYTNLCKFTKWIQETI 223 Query: 267 Q 267 Q Sbjct: 224 Q 224 >5ZFH-A nrPDB Length = 224 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 77/242 (31%), Positives = 117/242 (48%), Gaps = 25/242 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G + S PWQ++L LK + CGG L+ +VLTAAHC Y+V +G + Sbjct: 1 IIDGYKCKEGSHPWQVAL--LKGNQLH--CGGVLVDKYWVLTAAHC--KMGQYQVQLGSD 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 ++ D+ + H ++ NDI L++L E V++S ++ LPE Sbjct: 55 --KIGDQSAQKIKATKSFR-HPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEH--CE 109 Query: 150 PKDYPCYVTGWGRLWTNGP---IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 205 P C V+GWG T P L ++ C ++ + + KTM+CAG Sbjct: 110 PPGTSCTVSGWGT--TTSPDVTFPSDLMCSDVKLISSRECKKV--YKDLLGKTMLCAGIP 165 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 D + CNGDSGGPL C N + + G+VS+G+ C P VYT+V Y W+ E Sbjct: 166 DSKTNTCNGDSGGPLVC---NDTLQ--GLVSWGTYP-CGQPNDPGVYTQVCKYKRWVMET 219 Query: 266 MQ 267 M+ Sbjct: 220 MK 221 >6QHB-A nrPDB Length = 223 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 72/229 (31%), Positives = 114/229 (49%), Gaps = 19/229 (8%) Query: 40 SWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS 99 S P+Q +L + CGG LI +VLTAAHC +V +GK+NL ++ Sbjct: 11 SHPYQAALY----TSGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHNLGQQESSQE 64 Query: 100 LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTG 159 V + +H ++A DI L++LA +LS+ IQ LP + + C++ G Sbjct: 65 QSSVVRAV-IHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTTSCHILG 121 Query: 160 WGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV-ISACNGDSGG 218 WG+ +G D +Q +V C + ++ + M+CAG + +C GDSGG Sbjct: 122 WGKT-ADGDFPDTIQCAYIHLVSREECEHA--YPGQITQNMLCAGDEKYGKDSCQGDSGG 178 Query: 219 PLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 PL C + G+VS+G+ C +++KP VYT V Y +WI + +Q Sbjct: 179 PLVC-----GDHLRGLVSWGNIP-CGSKEKPGVYTNVCRYTNWIQKTIQ 221 >1TON-A nrPDB Length = 235 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 78/255 (30%), Positives = 120/255 (47%), Gaps = 40/255 (15%) Query: 30 VVGGEDARPHSWPWQISL--QYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVG 87 +VGG +S PWQ+++ +YL CGG LI ++V+TAAHC SN Y+V +G Sbjct: 1 IVGGYKCEKNSQPWQVAVINEYL--------CGGVLIDPSWVITAAHCYSN--NYQVLLG 50 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLL-----------RNDIALIKLAEHVELSDT 136 +NNL +DE + V H + L++ ND+ L+ L+E +++ Sbjct: 51 RNNL-FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGG 109 Query: 137 IQVACLPEKDSLLPK-DYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR--IDWWG 193 ++V LP K+ PK C +GWG + P + LQ V H + I+ + Sbjct: 110 VKVIDLPTKE---PKVGSTCLASGWG---STNPSEMVVSHDLQCVNIHLLSNEKCIETYK 163 Query: 194 FRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVY 252 V M+CAG +G C GDSGGPL C V ++ G C K P +Y Sbjct: 164 DNVTDVMLCAGEMEGGKDTCAGDSGGPLICD------GVLQGITSGGATPCAKPKTPAIY 217 Query: 253 TRVSAYIDWINEKMQ 267 ++ + WI + M+ Sbjct: 218 AKLIKFTSWIKKVMK 232 >1Q3X-A nrPDB Length = 328 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 86/279 (30%), Positives = 123/279 (44%), Gaps = 48/279 (17%) Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 +L C CG+ + R+ GG+ A+P +PWQ+ + T G L+ N+ Sbjct: 68 SLPVCEPVCGLSA--RTTGGRIYGGQKAKPGDFPWQVLI------LGGTTAAGALLYDNW 119 Query: 69 VLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTI-----HVHKRWNALLL----- 118 VLTAAH + E + + +L + + T+ H + W+ + Sbjct: 120 VLTAAHAV--------------YEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGY 165 Query: 119 ------RNDIALIKLAEHVELSDTIQVACLPEK--DSLLPKDYPCYVTGWGRLWTNGPIA 170 NDIALIKL V ++ I CLP K +S + D +GWG L G +A Sbjct: 166 THDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWG-LTQRGFLA 224 Query: 171 DKLQQGLQPVVDHATCS----RIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPL-NCQL 224 L P+VDH C+ + + V M+CAG + G +C GDSGG L Sbjct: 225 RNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDS 284 Query: 225 ENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 E W V GIVS+GS C + VYT+V YI WI Sbjct: 285 ETERWFVGGIVSWGSMN-CGEAGQYGVYTKVINYIPWIE 322 >1MZD-A nrPDB Length = 240 Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 117/247 (47%), Gaps = 23/247 (9%) Query: 29 RVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTYRVA 85 ++GG++ PHS P+ S+QY H CGG LI +VLTAAHC + ++ V Sbjct: 2 EIIGGKEVSPHSRPFMASIQY----GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVV 57 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 +G ++L ++E + + R + NDI L+KL +L+ +++ + K Sbjct: 58 LGAHSLS-KNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSK 116 Query: 146 DSLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFR--VKKTMVC 202 SL C VTGWG + +D L++ V+ C+ ++ + K MVC Sbjct: 117 TSLR-SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVC 175 Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVF-GIVSFGSRRGCNTRKKPVVYTRVS-AYI 259 AG G +C GD+GGPL C+ VF IVS G C KP +YT ++ Y Sbjct: 176 AGDAKGQKDSCKGDAGGPLICK------GVFHAIVSGGHE--CGVATKPGIYTLLTKKYQ 227 Query: 260 DWINEKM 266 WI + Sbjct: 228 TWIKSNL 234 >3VGC-B nrPDB Length = 131 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 49/132 (37%), Positives = 68/132 (51%), Gaps = 5/132 (3%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +V GE+A P SWPWQ+SLQ + T H CGG+LI N+V+TAAHC T V V Sbjct: 1 IVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAHC--GVTTSDVVVAGE 55 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + E + + + + ++N+L + NDI L+KL+ S T+ CLP Sbjct: 56 FDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDF 115 Query: 150 PKDYPCYVTGWG 161 C TGWG Sbjct: 116 AAGTTCVTTGWG 127 >1ZJK-A nrPDB Length = 403 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 85/279 (30%), Positives = 123/279 (44%), Gaps = 48/279 (17%) Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 +L C CG+ + ++ GG+ A+P +PWQ+ + T G L+ N+ Sbjct: 143 SLPVCEPVCGLSAR--TTGGQIYGGQKAKPGDFPWQVLI------LGGTTAAGALLYDNW 194 Query: 69 VLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTI-----HVHKRWNALLL----- 118 VLTAAH + E + + +L + + T+ H + W+ + Sbjct: 195 VLTAAHAV--------------YEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGY 240 Query: 119 ------RNDIALIKLAEHVELSDTIQVACLPEK--DSLLPKDYPCYVTGWGRLWTNGPIA 170 NDIALIKL V ++ I CLP K +S + D +GWG L G +A Sbjct: 241 THDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWG-LTQRGFLA 299 Query: 171 DKLQQGLQPVVDHATCS----RIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPL-NCQL 224 L P+VDH C+ + + V M+CAG + G +C GDSGG L Sbjct: 300 RNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDS 359 Query: 225 ENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 E W V GIVS+GS C + VYT+V YI WI Sbjct: 360 ETERWFVGGIVSWGSMN-CGEAGQYGVYTKVINYIPWIE 397 >1MD7-A nrPDB Length = 328 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 79/272 (29%), Positives = 126/272 (46%), Gaps = 33/272 (12%) Query: 13 CASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTA 72 C CG P P R++GG+ A+ ++PWQ+ N R GG L+ ++LTA Sbjct: 73 CLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQV----FTNIHGR--GGGALLGDRWILTA 126 Query: 73 AHCI-------SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIAL 124 AH + + + V +G N+E + G+ + ++H R + + DIAL Sbjct: 127 AHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIAL 186 Query: 125 IKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHA 184 ++L V L + CLP+ D+ YV+G+G + IA L+ PV + Sbjct: 187 LELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQ 244 Query: 185 TC-------SRIDWWGFRVKKTMVCAGGDGVIS-ACNGDSGGPLNCQLEN-GSWEVFGIV 235 C +R+D + + M CAG + AC GD+GG + N W GIV Sbjct: 245 ACENWLRGKNRMDVF----SQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIV 300 Query: 236 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 S+G GC+ + YT+V Y+DWI ++M+ Sbjct: 301 SWGI--GCS--RGYGFYTKVLNYVDWIKKEME 328 >1GPZ-A nrPDB Length = 399 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 79/272 (29%), Positives = 126/272 (46%), Gaps = 33/272 (12%) Query: 13 CASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTA 72 C CG P P +++GG+ A+ ++PWQ+ N R GG L+ ++LTA Sbjct: 141 CLPVCGKPVNPVEQRQQIIGGQKAKMGNFPWQV----FTNIHGRG--GGALLGDRWILTA 194 Query: 73 AHCI-------SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIAL 124 AH + + + V +G N+E + G+ + ++H R + + DIAL Sbjct: 195 AHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIAL 254 Query: 125 IKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHA 184 ++L V L + CLP+ D+ YV+G+G + IA L+ PV + Sbjct: 255 LELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQ 312 Query: 185 TC-------SRIDWWGFRVKKTMVCAGGDGVIS-ACNGDSGGPLNCQLEN-GSWEVFGIV 235 C +R+D + + M CAG + AC GDSGG + N W GIV Sbjct: 313 ACENWLRGKNRMDVF----SQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIV 368 Query: 236 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 S+G GC+ + YT+V Y+DWI ++M+ Sbjct: 369 SWGI--GCS--RGYGFYTKVLNYVDWIKKEME 396 >1GVZ-A nrPDB Length = 237 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 129/251 (51%), Gaps = 30/251 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + HS PWQ+++ + + CGG L+ +VLTAAHC+S+ Y++ +G++ Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGH----FQCGGVLVHPQWVLTAAHCMSD--DYQIWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQ 138 NL +DE+ + F V + +++ LL+ +D+ L++LA+ ++D ++ Sbjct: 55 NLS-KDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVK 197 + LP ++ L CY +GWG + T Q ++ + + C+R + ++ Sbjct: 114 ILDLPTQEPKLGS--TCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARA--YPEKMT 169 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + ++CA D S C GDSGG L C +G ++ GI S+G C V+T+V Sbjct: 170 EFVLCATHRDDSGSICLGDSGGALIC---DGVFQ--GITSWGYSE-CADFNDNFVFTKVM 223 Query: 257 AYIDWINEKMQ 267 + WI E ++ Sbjct: 224 PHKKWIKETIE 234 >3BSQ-A nrPDB Length = 227 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 74/242 (30%), Positives = 115/242 (47%), Gaps = 25/242 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G S PWQ++L L + CGG L+ +VLTAAHC N Y V +G + Sbjct: 1 IIDGAPCARGSHPWQVAL--LSGNQLH--CGGVLVNERWVLTAAHCKMN--EYTVHLGSD 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 L + + + H ++ ND+ L+KL LS ++ LP + Sbjct: 55 TL---GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR--CE 109 Query: 150 PKDYPCYVTGWGRLWTNGP---IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 205 P C V+GWG T P L ++ C+++ + ++ +M+CAG Sbjct: 110 PPGTTCTVSGWGT--TTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLCAGIP 165 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 D +ACNGDSGGPL C+ G+ + G+VS+G+ C P VYT+V + WIN+ Sbjct: 166 DSKKNACNGDSGGPLVCR---GTLQ--GLVSWGTFP-CGQPNDPGVYTQVCKFTKWINDT 219 Query: 266 MQ 267 M+ Sbjct: 220 MK 221 >4FXG-H nrPDB Length = 242 Score = 87.0 bits (214), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 115/257 (44%), Gaps = 46/257 (17%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 + GG+ A+P +PWQ+ + T G L+ N+VLTAAH + Sbjct: 1 IYGGQKAKPGDFPWQVLI------LGGTTAAGALLYDNWVLTAAHAV------------- 41 Query: 90 NLEVEDEEGSLFVGVDTI-----HVHKRWNALLL-----------RNDIALIKLAEHVEL 133 E + + +L + + T+ H + W+ + NDIALIKL V + Sbjct: 42 -YEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVI 100 Query: 134 SDTIQVACLPEK--DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCS---- 187 + I CLP K +S + D +GWG L G +A L P+VDH C+ Sbjct: 101 NSNITPICLPRKEAESFMRTDDIGTASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYE 159 Query: 188 RIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPL-NCQLENGSWEVFGIVSFGSRRGCNT 245 + + V M+CAG + G +C GD+GG L E W V GIVS+GS C Sbjct: 160 KPPYPRGSVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMN-CGE 218 Query: 246 RKKPVVYTRVSAYIDWI 262 + VYT+V YI WI Sbjct: 219 AGQYGVYTKVINYIPWI 235 >4LK4-A nrPDB Length = 357 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 110/245 (44%), Gaps = 12/245 (4%) Query: 25 NLSARVVGGEDARPHSWPWQISLQYLKNDTWR-HTCGGTLIASNFVLTAAHCISNTRTYR 83 ++S+R++ G +A WP ++L D ++ CGG+ + +VLTAAHC + Sbjct: 6 DISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAAS 65 Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP 143 V V ++ + + I+ H ++ L NDIA+++LA+ L I +A P Sbjct: 66 VDVIIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLP-AITLAG-P 123 Query: 144 EKDSLLPKDYPCYVTGWGRLWTNGP--IADKLQQGLQPVVDHATCSRIDWWGFRV--KKT 199 + LP P V GWG + P LQ+ +V + C + G T Sbjct: 124 ATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNST 183 Query: 200 MVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYI 259 CA +C GD+GGP+ + E GIVS+G + C VYT VS + Sbjct: 184 NFCA-ARLTKDSCQGDAGGPI---VVKTGREQLGIVSWGDEQ-CAKTGTYGVYTNVSYFR 238 Query: 260 DWINE 264 DWI + Sbjct: 239 DWITK 243 >3S9B-A nrPDB Length = 234 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 105/235 (44%), Gaps = 13/235 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG++ + P+ ++L + T C G LI +VLTAAHC + R R+ +G + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH--CAGALINREWVLTAAHC--DRRNIRIKLGMH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + + +E+ + V L DI LI+L V S I LP + + Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 C + GWG++ T D +V H C + W +T+ G Sbjct: 117 GSR--CRIMGWGKISTTT-YPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGR 173 Query: 210 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 C+GDSGGPL C NG E+ GIV+ GS C KP VYT+V Y +WI Sbjct: 174 DTCHGDSGGPLIC---NG--EMHGIVAGGS-EPCGQHLKPAVYTKVFDYNNWIQS 222 >3RU4-E nrPDB Length = 96 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 43/96 (44%), Positives = 65/96 (67%), Gaps = 6/96 (6%) Query: 171 DKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWE 230 D+LQQ P++ + C + +WG ++K M+CAG GV S+C GDSGGPL C+ +NG+W Sbjct: 4 DRLQQASLPLLSNTNCKK--YWGTKIKDAMICAGASGV-SSCMGDSGGPLVCK-KNGAWT 59 Query: 231 VFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + GIVS+GS C+T P VY RV+A ++W+ + + Sbjct: 60 LVGIVSWGSST-CST-STPGVYARVTALVNWVQQTL 93 >1AE5-A nrPDB Length = 225 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 110/240 (45%), Gaps = 32/240 (13%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--SNTRTYRVAVG 87 +VGG ARP +P+ S+Q + RH CGG LI + FV+TAA C N V +G Sbjct: 1 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +L + + + ++ + ++ ND+ L++L L+ ++ + LP +++ Sbjct: 57 AYDLRRRERQSRQTFSISSMSENG-YDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 115 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 + C V GWG + G ++ P + T + D + + VC G Sbjct: 116 TVEAGTRCQVAGWGSQRSGGRLSRF------PRFVNVTVTPED----QCRPNNVCT---G 162 Query: 208 VISA----CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 V++ CNGD G PL C+ G+ SF S C + P +TRV+ + DWI+ Sbjct: 163 VLTRRGGICNGDGGTPLVCE-----GLAHGVASF-SLGPCG--RGPDFFTRVALFRDWID 214 >1SI5-H nrPDB Length = 240 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 65/227 (28%), Positives = 109/227 (48%), Gaps = 20/227 (8%) Query: 43 WQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--SNTRTYRVAVGKNNLEVE-DEEGS 99 W +SL+Y +H CGG+LI ++VLTA C + + Y +G +++ DE+ Sbjct: 13 WMVSLRYRN----KHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCK 68 Query: 100 LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTG 159 + V + + D+ L+KLA L D + LP S +P+ C V G Sbjct: 69 QVLNVSQLVYGPEGS------DLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYG 122 Query: 160 WGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISA-CNGDSG 217 WG +T D L + ++ + CS+ + ++ +CAG + + S C GD G Sbjct: 123 WG--YTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYG 180 Query: 218 GPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 GPL C+ ++ V G++ G RGC +P ++ RV+ Y WI++ Sbjct: 181 GPLVCE-QHKMRMVLGVIVPG--RGCAIPNRPGIFVRVAYYAKWIHK 224 >4E7N-A nrPDB Length = 238 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 72/237 (30%), Positives = 115/237 (48%), Gaps = 17/237 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG++ + + ++L ++ T CGGTLI +VLTAAHC + + +R+ +G + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTL--FCGGTLINQEWVLTAAHC--DRKNFRIKLGMH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + +V +E+ V + N L DI LI+L V+ ++ +A S Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVK--NSKHIAPFSLPSSPP 114 Query: 150 PKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKT--MVCAG-G 205 C + GWGR+ T G D ++++ C R + F + T +CAG Sbjct: 115 SVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMC-RAPYPEFELPATSRTLCAGIL 173 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 +G C GDSGGPL C NG ++ GI S+G C KP YT+V ++DWI Sbjct: 174 EGGKDTCKGDSGGPLIC---NGQFQ--GIASWGDDP-CAQPHKPAAYTKVFDHLDWI 224 >2QY0-B nrPDB Length = 242 Score = 80.1 bits (196), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 120/255 (47%), Gaps = 33/255 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI-------SNTRTY 82 ++GG+ A+ ++PWQ+ N R GG L+ ++LTAAH + + + Sbjct: 1 IIGGQKAKMGNFPWQV----FTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASL 54 Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVAC 141 V +G N+E + G+ + ++H R + + DIAL++L V L + C Sbjct: 55 DVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 114 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATC-------SRIDWWGF 194 LP+ D+ YV+G+G + IA L+ PV + C +R+D + Sbjct: 115 LPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVF-- 170 Query: 195 RVKKTMVCAGGDGVIS-ACNGDSGGPLNCQLEN-GSWEVFGIVSFGSRRGCNTRKKPVVY 252 + M CAG + AC GDSGG + N W GIVS+G GC+ + Y Sbjct: 171 --SQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI--GCS--RGYGFY 224 Query: 253 TRVSAYIDWINEKMQ 267 T+V Y+DWI ++M+ Sbjct: 225 TKVLNYVDWIKKEME 239 >2AIQ-A nrPDB Length = 231 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 68/206 (33%), Positives = 98/206 (47%), Gaps = 15/206 (7%) Query: 59 CGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 CGGTLI +VLTA HC + R+ +G +NL+V +++ + N + Sbjct: 25 CGGTLINQEWVLTARHC--DRGNMRIYLGMHNLKVLNKDALRRFPKEKYFCLNTRNDTIW 82 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWT-NGPIADKLQQGL 177 DI LI+L V S I LP + C + GWG + + N + D Sbjct: 83 DKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV--GSVCRIMGWGTITSPNATLPDVPHCAN 140 Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVS 236 ++D+A C + + G T +CAG +G C GDSGGPL C NG ++ GI+S Sbjct: 141 INILDYAVC-QAAYKGL--AATTLCAGILEGGKDTCKGDSGGPLIC---NGQFQ--GILS 192 Query: 237 FGSRRGCNTRKKPVVYTRVSAYIDWI 262 G C +KP +YT+V Y DWI Sbjct: 193 VGGNP-CAQPRKPGIYTKVFDYTDWI 217 >1PQ7-A nrPDB Length = 224 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 106/240 (44%), Gaps = 25/240 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN--TRTYRVAVG 87 +VGG A +P+ +S+ W CGG+L+ +N VLTAAHC+S +++ G Sbjct: 1 IVGGTSASAGDFPFIVSISR-NGGPW---CGGSLLNANTVLTAAHCVSGYAQSGFQIRAG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + G + + ++ VH ++ ND+A++KL+ + I A L S Sbjct: 57 ----SLSRTSGGITSSLSSVRVHPSYSG--NNNDLAILKLSTSIPSGGNIGYARLAASGS 110 Query: 148 LLPKDYPCYVTGWGRLWTNG---PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG 204 V GWG G P+ L + P+V ATC R + + M CAG Sbjct: 111 DPVAGSSATVAGWGATSEGGSSTPV--NLLKVTVPIVSRATC-RAQYGTSAITNQMFCAG 167 Query: 205 -GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 G +C GDSGGP + + S + G VS+G GC VY V A +I+ Sbjct: 168 VSSGGKDSCQGDSGGP----IVDSSNTLIGAVSWG--NGCARPNYSGVYASVGALRSFID 221 >3I77-A nrPDB Length = 230 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 77/239 (32%), Positives = 104/239 (43%), Gaps = 22/239 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 87 VVGG A +P+ + L +N+ + CGG L A + VLTAAHC+S + T A G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGF---CGGALYAQDIVLTAAHCVSGSGNNTSITATG 57 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKR--WNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 V D + S V V + V + + D ALIKLA+ + T+++A Sbjct: 58 G----VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPIN-QPTLKIATTTAY 112 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 + V GWG G L + P V A C + V M+CAG Sbjct: 113 N-----QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF-ILVANEMICAGY 166 Query: 205 -GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 G + C GDSGGP+ + W GIVS+G GC P VYT VS + I Sbjct: 167 PDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG--YGCARPGYPGVYTEVSTFASAI 223 >5LPF-A nrPDB Length = 234 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 75/243 (30%), Positives = 109/243 (44%), Gaps = 39/243 (16%) Query: 40 SWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS 99 S PWQ+SL + C G L+ ++VLTAAHC + VG ++L + E Sbjct: 14 SQPWQVSL----FNGLSFHCAGVLVDQSWVLTAAHC--GNKPLWARVGDDHLLLLQGEQL 67 Query: 100 LFVGVDTIH--VHKRWNALLLR----NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDY 153 +H H+ +L R +D+ L+KLA V L ++ LP + + P D Sbjct: 68 RRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ-PGDQ 126 Query: 154 PCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRID---------WWGFRVKKTMVCAG 204 C V GWG T K +GL TCS I ++ V M+CAG Sbjct: 127 -CQVAGWG---TTAARRVKYNKGL-------TCSSITILSPKECEVFYPGVVTNNMICAG 175 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 D C DSGGPL C + GI+S+G C + + P VYT++ Y+ WIN+ Sbjct: 176 LDRGQDPCQSDSGGPLVC-----DETLQGILSWGVYP-CGSAQHPAVYTQICKYMSWINK 229 Query: 265 KMQ 267 ++ Sbjct: 230 VIR 232 >4WJG-C nrPDB Length = 315 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 83/286 (29%), Positives = 119/286 (41%), Gaps = 53/286 (18%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C + CG P P N R++GG S+PWQ + N T G TLI ++ Sbjct: 51 LPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHN----LTTGATLINEQWL 106 Query: 70 LTAA------HCISNTR-----TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 LT A H + T T + VGK L V ++ + +H ++ + Sbjct: 107 LTTAKNLFLNHSENATAKDIAPTLTLYVGKKQL----------VEIEKVVLHPNYSQV-- 154 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178 DI LIKL + V +++ + CLP KD YV+GWGR N D L+ + Sbjct: 155 --DIGLIKLKQKVSVNERVMPICLPSKD-YAEVGRVGYVSGWGRN-ANFKFTDHLKYVML 210 Query: 179 PVVDHATCSRIDWWGFRV--KKT--------------MVCAGGDGVIS-ACNGDSGGPLN 221 PV D C R + G V KKT CAG C GD+G Sbjct: 211 PVADQDQCIR-HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFA 269 Query: 222 CQ-LENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 LE +W GI+SF + C + VY +V++ DW+ + + Sbjct: 270 VHDLEEDTWYATGILSFD--KSCAVAEYG-VYVKVTSIQDWVQKTI 312 >2JET-C nrPDB Length = 99 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 43/97 (44%), Positives = 60/97 (61%), Gaps = 6/97 (6%) Query: 171 DKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWE 230 +KLQQ P+V A C + WG ++ M CAG GV S C GDSGGPL CQ ++G W Sbjct: 7 EKLQQAALPIVSEADCKKS--WGSKITDVMTCAGASGVDS-CMGDSGGPLVCQ-KDGVWT 62 Query: 231 VFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + GIVS+GS G + P VY+RV+A + W+ + ++ Sbjct: 63 LAGIVSWGS--GVCSTSTPGVYSRVTALMPWVQQILE 97 >4GSO-A nrPDB Length = 232 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 70/238 (29%), Positives = 111/238 (46%), Gaps = 17/238 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG++ + P+ L +L + + CG TLI +V+TAAHC ++ +++ +G + Sbjct: 1 VLGGDECDINEHPF---LAFLYSHGYF--CGLTLINQEWVVTAAHC--DSTNFQMQLGVH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + +V +E+ + + + +L DI LIKL + + S I LP + Sbjct: 54 SKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV 113 Query: 150 PKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 C + GWG + N D +VD+ C + G K T+ +G Sbjct: 114 GS--VCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGA-YNGLPAKTTLCAGVLEGG 170 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C GDSGGPL C NG ++ GIVS+G+ C KP +YT V Y DWI + Sbjct: 171 KDTCVGDSGGPLIC---NGQFQ--GIVSYGAHS-CGQGPKPGIYTNVFDYTDWIQRNI 222 >1BQY-A nrPDB Length = 234 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 69/206 (33%), Positives = 100/206 (48%), Gaps = 13/206 (6%) Query: 59 CGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 CGGTLI ++V+TAAHC SN +++ G ++ ++ +E+ + R + Sbjct: 26 CGGTLINQDWVVTAAHCDSN--NFQLLFGVHSKKILNEDEQTRDPKEKFFCPNRKKDDEV 83 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178 DI LIKL V S++ +A L S C + GWG+ I + Sbjct: 84 DKDIMLIKLDSSV--SNSEHIAPLSLPSSPPSVGSVCRIMGWGKTIPTKEIYPDVPHCAN 141 Query: 179 -PVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVS 236 ++DHA C W +V T +CAG G C+ DSGGPL C NG ++ GIVS Sbjct: 142 INILDHAVCRTAYSWR-QVANTTLCAGILQGGRDTCHFDSGGPLIC---NGIFQ--GIVS 195 Query: 237 FGSRRGCNTRKKPVVYTRVSAYIDWI 262 +G C +P VYT+V Y+DWI Sbjct: 196 WGGHP-CGQPGEPGVYTKVFDYLDWI 220 >2FMJ-A nrPDB Length = 222 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 101/236 (42%), Gaps = 24/236 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 87 VVGG A +P+ + L CGG L A + VLTAAHC+S + T A G Sbjct: 1 VVGGTRAAQGEFPFMVRLS--------MGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 V D + S V V + V + D ALIKLA+ + T+++A + Sbjct: 53 G----VVDLQSSSAVKVRSTKVLQAPGYNGTGKDWALIKLAQPIN-QPTLKIATTTAYN- 106 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD- 206 V GWG G L + P V A C R + V +CAG D Sbjct: 107 ----QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAAC-RSAYGNELVANEEICAGYDT 161 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 G + C GDSGGP+ + W GIVS+G GC + K VYT VS + I Sbjct: 162 GGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG--EGCARKGKYGVYTEVSTFASAI 215 >1OP0-A nrPDB Length = 234 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 66/215 (30%), Positives = 104/215 (48%), Gaps = 23/215 (10%) Query: 59 CGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 CGGTLI +V+TAAHC ++ +++ +G ++ +V +E+ + + N +L Sbjct: 26 CGGTLINPEWVVTAAHC--DSTDFQMQLGVHSKKVLNEDEQTRNPKEKFICPNKNNNEVL 83 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRL------WTNGPIADK 172 DI LIKL + +S++ +A L S C + GWG + + + P Sbjct: 84 DKDIMLIKLDK--PISNSKHIAPLSLPSSPPSVGSVCRIMGWGSITPVKETFPDVPYCAN 141 Query: 173 LQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEV 231 + ++DHA C + + + +CAG G C GDSGGPL C NG ++ Sbjct: 142 IN-----LLDHAVC-QAGYPELLAEYRTLCAGIVQGGKDTCGGDSGGPLIC---NGQFQ- 191 Query: 232 FGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 GIVS+G+ C KP +YT V Y DWI + Sbjct: 192 -GIVSYGAHP-CGQGPKPGIYTNVFDYTDWIQRNI 224 >5XW8-A nrPDB Length = 133 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 10/141 (7%) Query: 22 FPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT 81 FP + ++VGG +S P+Q+SL ++ H CGG+LI S +V++AAHC + Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKS--R 53 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +V +G++N++V E F+ I H +N L NDI LIKL+ L+ + Sbjct: 54 IQVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 112 Query: 142 LPEKDSLLPKDYPCYVTGWGR 162 LP S C ++GWG Sbjct: 113 LPR--SCAAAGTECLISGWGN 131 >4X0L-C nrPDB Length = 259 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 116/279 (41%), Gaps = 53/279 (18%) Query: 17 CGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAA--- 73 CG P P N R++GG S+PWQ + N T G TLI ++LT A Sbjct: 2 CGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHN----LTTGATLINEQWLLTTAKNL 57 Query: 74 ---HCISNTR-----TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALI 125 H + T T + VGK L V ++ + +H ++ + DI LI Sbjct: 58 FLNHSENATAKDIAPTLTLYVGKKQL----------VEIEKVVLHPNYSQV----DIGLI 103 Query: 126 KLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHAT 185 KL + V +++ + CLP KD YV+GWGR N D L+ + PV D Sbjct: 104 KLKQKVSVNERVMPICLPSKD-YAEVGRVGYVSGWGRN-ANFKFTDHLKYVMLPVADQDQ 161 Query: 186 CSRIDWWGFRV--KKT--------------MVCAGGDGVIS-ACNGDSGGPLNCQ-LENG 227 C R + G V KKT CAG C GD+G LE Sbjct: 162 CIR-HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEED 220 Query: 228 SWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +W GI+SF + C + VY +V++ DW+ + + Sbjct: 221 TWYATGILSFD--KSCAVAEYG-VYVKVTSIQDWVQKTI 256 >4F4O-C nrPDB Length = 347 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 83/283 (29%), Positives = 120/283 (42%), Gaps = 53/283 (18%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C + CG P P + R++GG S+PWQ + N T G TLI ++ Sbjct: 83 LPECEAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHN----LTSGATLINEQWL 138 Query: 70 LTAAHCI-----SNTR------TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 LT A + ++T+ T R+ VGK EVE E+ T+ Sbjct: 139 LTTAKNLRLGHKNDTKAKDIAPTLRLYVGKKQ-EVEIEKVIFHPDNSTV----------- 186 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178 DI LIKL + V +++ + CLP KD + YV+GWGR N + L+ + Sbjct: 187 --DIGLIKLKQKVPVNERVMPICLPSKD-YVNVGLVGYVSGWGRN-ANLNFTEHLKYVML 242 Query: 179 PVVDHATCSRIDWWGFRV--KKT--------------MVCAG-GDGVISACNGDSGGPLN 221 PV D C + + G V KKT CAG C GD+G Sbjct: 243 PVADQEKCVQY-YEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFA 301 Query: 222 CQ-LENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 ++ +W GI+SF + C T + VY RV++ +DWI Sbjct: 302 VHDKDDDTWYAAGILSFD--KSCRTAEYG-VYVRVTSILDWIQ 341 >5XRF-A nrPDB Length = 242 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 73/247 (29%), Positives = 111/247 (44%), Gaps = 33/247 (13%) Query: 27 SARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAV 86 S V+GG + + + + + + W C GTLI +VL AAHC R + + Sbjct: 4 SELVIGGNECDTNEHRFLAA--FFTSRPWTFQCAGTLIHEEWVLAAAHCYK--RGLNIYL 59 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G +N ++ ++ ++ + D+ L+KL + V S++ +A L Sbjct: 60 GMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPV--SNSTHIAPLSLPS 117 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFR--------VKK 198 S C V GWG + + I P V H C+ I+ + V + Sbjct: 118 SPPSIGSVCRVMGWGIMSSTKDIL--------PDVPH--CANINLLNYMECVAHYPDVPE 167 Query: 199 T--MVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 T ++CAG +G I CN DSGGPL C +G ++ GIV FG + C KP +YTRV Sbjct: 168 TTRLLCAGVLEGGIDTCNQDSGGPLIC---DGQFQ--GIVFFG-KYPCAQPNKPGLYTRV 221 Query: 256 SAYIDWI 262 S Y DWI Sbjct: 222 SNYNDWI 228 >3BEU-A nrPDB Length = 224 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 76/238 (31%), Positives = 100/238 (42%), Gaps = 26/238 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 87 VVGG A +P+ + L CGG L A + VLTAAHC+S + T A G Sbjct: 1 VVGGTRAAQGEFPFMVRLS--------MGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKR--WNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 V D + S V V + V + + D ALIKLA+ + T+++A Sbjct: 53 G----VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPIN-QPTLKIATTTAY 107 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 + V GWG G L + P V A C + V M+CAG Sbjct: 108 N-----QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF-ILVANEMICAGY 161 Query: 206 DGVIS-ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 D C GDSGGP+ + W GIVS+G GC + K VYT VS + I Sbjct: 162 DTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWG--EGCARKGKYGVYTEVSTFASAI 217 >1BBR-H nrPDB Length = 150 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 50/144 (34%), Positives = 72/144 (50%), Gaps = 14/144 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G+DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + + +D I++H R+N L DIAL+KL +ELSD I Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 141 CLPEKDS---LLPKDYPCYVTGWG 161 CLP+K + LL + VTGWG Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWG 142 >1RIW-B nrPDB Length = 147 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 50/146 (34%), Positives = 71/146 (48%), Gaps = 14/146 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + ++ I++H R+N L DIAL+KL + V SD I Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 141 CLPEKD---SLLPKDYPCYVTGWGRL 163 CLP+++ SLL Y VTGWG L Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNL 144 >3S69-A nrPDB Length = 234 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 69/209 (33%), Positives = 99/209 (47%), Gaps = 19/209 (9%) Query: 59 CGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 C GTLI +VLTAAHC + +++ +G ++ +V +E+ + + N +L Sbjct: 26 CSGTLINEEWVLTAAHC--DNTNFQMKLGVHSKKVLNEDEQTRNPKEKFICPNKKNDEVL 83 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIA----DKLQ 174 DI LIKL V S+ I LP + C++ GWG + PI D Sbjct: 84 DKDIMLIKLDSRVSNSEHIVPLSLPSSPPSVGS--VCHIMGWGSIT---PIKVTYPDVPY 138 Query: 175 QGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFG 233 ++D A C + + + +CAG +G C GDSGGPL C NG ++ G Sbjct: 139 CAYINLLDDAVC-QAGYPELLTEYRTLCAGILEGGKDTCGGDSGGPLIC---NGQFQ--G 192 Query: 234 IVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 IVSFG+ C KP VYT+V Y WI Sbjct: 193 IVSFGAHP-CGQGLKPGVYTKVFDYNHWI 220 >2PKA-B nrPDB Length = 152 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 49/153 (32%), Positives = 82/153 (53%), Gaps = 16/153 (10%) Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGP----IADKLQ 174 +D+ L++L +++D ++V LP ++ L C +GWG + GP D++Q Sbjct: 7 SHDLMLLRLQSPAKITDAVKVLELPTQEPELGST--CEASGWGSI-EPGPDDFEFPDEIQ 63 Query: 175 QGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFG 233 ++ + C+ D +V ++M+CAG G C GDSGGPL C NG W+ G Sbjct: 64 CVQLTLLQNTFCA--DAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLIC---NGMWQ--G 116 Query: 234 IVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 I S+G C + KP +YT++ Y+DWI++ + Sbjct: 117 ITSWG-HTPCGSANKPSIYTKLIFYLDWIDDTI 148 >3H7O-A nrPDB Length = 228 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 58/234 (24%), Positives = 107/234 (45%), Gaps = 13/234 (5%) Query: 32 GGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNL 91 GGE PW ++++ + TCGG +++ FVLTAAHC+ + + + + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEE-SLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYEST 60 Query: 92 EVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSD-TIQVACLPEKDSLLP 150 + ++ G V +++ + + NDIA+++L+ ++L + A LP+ + Sbjct: 61 NLWEDPGKSDPYVSHVYLS-FYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 151 KDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVIS 210 V+G+G T P L+ VVD C R + + + CA GV S Sbjct: 120 TGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDEC-RTKYGPIFLSLQVFCAQKVGV-S 177 Query: 211 ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +GD+G P Q + G+ ++ +R P V+T+V +Y+ WI + Sbjct: 178 LESGDAGDPTVQQD-----TLVGVAAYFPKR---PEGAPEVFTKVGSYVSWIQD 223 >3H5C-B nrPDB Length = 317 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 59/229 (25%), Positives = 97/229 (42%), Gaps = 22/229 (9%) Query: 42 PWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLF 101 PWQ+ L N + CGG +I NFVLT A C R V N + L Sbjct: 106 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFN----RTSQDPLM 158 Query: 102 VGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS----LLPKDYPCYV 157 + + +HVH R++A ND++L++L ++ C PEKD L+P+ + Sbjct: 159 IKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRG-LL 217 Query: 158 TGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSG 217 +GW R T+ + + L +V+ C ++ V T ++A + G Sbjct: 218 SGWARNGTD--LGNSLTTRPVTLVEGEECGQV----LNVTVTTRTYCERSSVAAMHWMDG 271 Query: 218 GPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + + GSW + G++ G + V+ T+VS Y W + M Sbjct: 272 SVVT-REHRGSWFLTGVLGSQPVGG---QAHMVLVTKVSRYSLWFKQIM 316 >3F1S-B nrPDB Length = 283 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 59/229 (25%), Positives = 97/229 (42%), Gaps = 22/229 (9%) Query: 42 PWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLF 101 PWQ+ L N + CGG +I NFVLT A C R V N + L Sbjct: 65 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFN----RTSQDPLM 117 Query: 102 VGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS----LLPKDYPCYV 157 + + +HVH R++A ND++L++L ++ C PEKD L+P+ + Sbjct: 118 IKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRG-LL 176 Query: 158 TGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSG 217 +GW R T+ + + L +V+ C ++ V T ++A + G Sbjct: 177 SGWARNGTD--LGNSLTTRPVTLVEGEECGQV----LNVTVTTRTYCERSSVAAMHWMDG 230 Query: 218 GPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + + GSW + G++ G + V+ T+VS Y W + M Sbjct: 231 SVVT-REHRGSWFLTGVLGSQPVGG---QAHMVLVTKVSRYSLWFKQIM 275 >1DLE-A nrPDB Length = 298 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 68/274 (24%), Positives = 109/274 (39%), Gaps = 52/274 (18%) Query: 39 HSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRVAVG--KNNLEV 93 H PWQ + ++ +C G +++ FVLTAAHC + + +V+VG K +LE+ Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEI 84 Query: 94 EDEEGSLFVGVDTIHVHKRWNALLLRN-DIALIKLAEHVELSDTIQVACLP--------- 143 E LF I+ K + D+ALIKL ++ TI+ CLP Sbjct: 85 ---EVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRAL 141 Query: 144 ----------EKDSLLPKD--YPCYVTGWGRLWT-------NGPIADKLQQGLQPVVDHA 184 +K+ LLP +V+ + T NG ++ Q + Sbjct: 142 RLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYD 201 Query: 185 TCSRIDWWGFRVKKTMVCAGGDGVIS---ACNGDSGGPLNCQLENGSWEVFGIVSFGSRR 241 I V +C GG + C GDSGGPL + +V G++S+G Sbjct: 202 KVKDISEV---VTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV-GVISWGVVD 257 Query: 242 GCNTRKKPV--------VYTRVSAYIDWINEKMQ 267 C +K+ + + + W+ EK+Q Sbjct: 258 VCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >2WIN-I nrPDB Length = 507 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/274 (24%), Positives = 109/274 (39%), Gaps = 52/274 (18%) Query: 39 HSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRVAVG--KNNLEV 93 H PWQ + ++ +C G +++ FVLTAAHC + + +V+VG K +LE+ Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEI 291 Query: 94 EDEEGSLFVGVDTIHVHKRWNALLLRN-DIALIKLAEHVELSDTIQVACLP--------- 143 E LF I+ K + D+ALIKL ++ TI+ CLP Sbjct: 292 ---EVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRAL 348 Query: 144 ----------EKDSLLPKD--YPCYVTGWGRLWT-------NGPIADKLQQGLQPVVDHA 184 +K+ LLP +V+ + T NG ++ Q + Sbjct: 349 RLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYD 408 Query: 185 TCSRIDWWGFRVKKTMVCAGGDGVIS---ACNGDSGGPLNCQLENGSWEVFGIVSFGSRR 241 I V +C GG + C GDSGGPL + +V G++S+G Sbjct: 409 KVKDISEV---VTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV-GVISWGVVD 464 Query: 242 GCNTRKKPV--------VYTRVSAYIDWINEKMQ 267 C +K+ + + + W+ EK+Q Sbjct: 465 VCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 498 >2OK5-A nrPDB Length = 752 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 68/274 (24%), Positives = 109/274 (39%), Gaps = 52/274 (18%) Query: 39 HSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRVAVG--KNNLEV 93 H PWQ + ++ +C G +++ FVLTAAHC + + +V+VG K +LE+ Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEI 535 Query: 94 EDEEGSLFVGVDTIHVHKRWNALLLRN-DIALIKLAEHVELSDTIQVACLP--------- 143 E LF I+ K + D+ALIKL ++ TI+ CLP Sbjct: 536 ---EVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRAL 592 Query: 144 ----------EKDSLLPKD--YPCYVTGWGRLWT-------NGPIADKLQQGLQPVVDHA 184 +K+ LLP +V+ + T NG ++ Q + Sbjct: 593 RLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYD 652 Query: 185 TCSRIDWWGFRVKKTMVCAGGDGVIS---ACNGDSGGPLNCQLENGSWEVFGIVSFGSRR 241 I V +C GG + C GDSGGPL + +V G++S+G Sbjct: 653 KVKDISEV---VTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV-GVISWGVVD 708 Query: 242 GCNTRKKPV--------VYTRVSAYIDWINEKMQ 267 C +K+ + + + W+ EK+Q Sbjct: 709 VCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >3H7T-A nrPDB Length = 235 Score = 53.5 bits (127), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 57/237 (24%), Positives = 111/237 (46%), Gaps = 23/237 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG+ + PW + + L ++ + CGG+++ +NFV+TAA C+ T+ +++ Sbjct: 1 IIGGKKSDITKEPWAVGV--LVDE--KPFCGGSILTANFVITAAQCVDGTKPSDISIHYG 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSD-TIQVACLPEKDSL 148 + + S+ I++ R++ L ++N+ A+I+ ++L D T + LP Sbjct: 57 SSYRTTKGTSVM--AKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYD 113 Query: 149 LPKDYPCYVTGWGRL-WTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTM----VCA 203 D V+GWG + + + L + VVD +C + K + CA Sbjct: 114 PEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEE-QYKQIEADKYIYDGVFCA 172 Query: 204 GGDGVISACN-GDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYI 259 GG+ + GD+G P ++NG+ + G+ S+ S + P V+ RV Y+ Sbjct: 173 GGEYDETYIGYGDAGDP---AVQNGT--LVGVASYISSM---PSEFPSVFLRVGYYV 221 >1AKS-B nrPDB Length = 98 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/89 (38%), Positives = 54/89 (60%), Gaps = 10/89 (11%) Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237 PV+ +++C + + G ++ M+C G G +C GDSGGP+ C NG ++ GIVS+ Sbjct: 16 PVLSNSSC-KSSYPG-QITGNMICVGFLQGGKDSCQGDSGGPVVC---NG--QLQGIVSW 68 Query: 238 GSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 G GC + KP VYT+V Y++WI + + Sbjct: 69 G--YGCAQKNKPGVYTKVCNYVNWIQQTI 95 >2KAI-A nrPDB Length = 80 Score = 50.8 bits (120), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 7/85 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + +S PWQ+++ + + CGG L+ +VLTAAHC ++ Y V +G++ Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSS----FQCGGVLVNPKWVLTAAHCKND--NYEVWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWN 114 NL E+E + F GV H +N Sbjct: 55 NL-FENENTAQFFGVTADFPHPGFN 78 >2I6S-A nrPDB Length = 517 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 68/276 (24%), Positives = 108/276 (39%), Gaps = 66/276 (23%) Query: 17 CGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI 76 CGV + N S + PW ++++ + TC G LI+ +VLTAAHC Sbjct: 228 CGVGNMSANASDQ---------ERTPWHVTIK----PKSQETCRGALISDQWVLTAAHCF 274 Query: 77 SNTRTY---RVAVGKNN----LEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAE 129 + + RV VG E E+ + G D + +DIAL+KLA+ Sbjct: 275 RDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQ 334 Query: 130 HVELSDTIQVACLP--------------------EKDSLLPKDYPCYVTGWGRLWTNGPI 169 V++S + CLP E + L + P + NG Sbjct: 335 KVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVAL-----NG-- 387 Query: 170 ADKLQQGLQPVVDHATCSRI---------DWWGFR--VKKTMVCAGGDGVISACNGDSGG 218 KL L+ V+ +C+ + + R V +C+G S C G+SGG Sbjct: 388 -SKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGG 446 Query: 219 PLNCQLENGSWEVFGIVSFGSRRGC------NTRKK 248 + + ++V G+VS+G C N+RK+ Sbjct: 447 AVFLERRFRFFQV-GLVSWGLYNPCLGSADKNSRKR 481 >2HNT-E nrPDB Length = 81 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 28/64 (43%), Positives = 38/64 (59%), Gaps = 4/64 (6%) Query: 104 VDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVACLPEKD---SLLPKDYPCYVTG 159 ++ I++H R+N L DIAL+KL + V SD I CLP+++ SLL Y VTG Sbjct: 8 LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTG 67 Query: 160 WGRL 163 WG L Sbjct: 68 WGNL 71 >1BBR-E nrPDB Length = 109 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 15/94 (15%) Query: 179 PVVDHATC---SRIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWE 230 P+V+ C +RI R+ M CAG G+G AC GDSGGP + N W Sbjct: 16 PLVERPVCKASTRI-----RITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWY 70 Query: 231 VFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 GIVS+G GC+ K YT V WI + Sbjct: 71 QMGIVSWGE--GCDRDGKYGFYTHVFRLKKWIQK 102 >2HNT-F nrPDB Length = 105 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/95 (35%), Positives = 41/95 (43%), Gaps = 17/95 (17%) Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAG--------GDGVISACNGDSGGPLNCQLE-NGSW 229 P+V+ C D R+ M CAG GD AC GDSGGP + N W Sbjct: 12 PIVERPVCK--DSTRIRITDNMFCAGYKPDEGKRGD----ACEGDSGGPFVMKSPFNNRW 65 Query: 230 EVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 GIVS+G GC+ K YT V WI + Sbjct: 66 YQMGIVSWGE--GCDRDGKYGFYTHVFRLKKWIQK 98 >1EPT-B nrPDB Length = 82 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142 +V +G++N++V E F+ I H +N L NDI LIKL+ L+ + L Sbjct: 4 QVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 62 Query: 143 PEKDSLLPKDYPCYVTGWG 161 P S C ++GWG Sbjct: 63 PR--SCAAAGTECLISGWG 79 >2HNT-C nrPDB Length = 70 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI 76 +V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCL 45 >1P3E-A nrPDB Length = 215 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 15/27 (55%), Positives = 19/27 (70%), Gaps = 2/27 (7%) Query: 58 TCGGTLIASNFVLTAAHCISNT--RTY 82 +C GTLIA N +LT HC+ NT R+Y Sbjct: 31 SCTGTLIAPNKILTNGHCVYNTASRSY 57 >4V8P-BH nrPDB Length = 215 Score = 27.3 bits (59), Expect = 7.7, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 16/38 (42%) Query: 183 HATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPL 220 H C W R+ K + CAG D + S G G L Sbjct: 86 HLRCRVHPWHVLRINKMLSCAGADRLQSGMRGAFGKAL 123 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4H4F-A nrPDB 357 3e-99 1PYT-D nrPDB 344 3e-95 1BRU-P nrPDB 321 1e-88 3T2N-A nrPDB 292 1e-79 1F7Z-A nrPDB 291 2e-79 2V35-A nrPDB 291 2e-79 5FXL-A nrPDB 289 9e-79 4AN7-A nrPDB 289 9e-79 5TJX-A nrPDB 289 1e-78 6I44-A nrPDB 287 3e-78 1FON-A nrPDB 287 3e-78 1UTJ-A nrPDB 286 5e-78 1ELT-A nrPDB 285 1e-77 2F83-A nrPDB 283 5e-77 5GVT-A nrPDB 283 5e-77 4WWY-A nrPDB 280 3e-76 1FI8-A nrPDB 280 6e-76 1A0J-A nrPDB 279 7e-76 5UGG-A nrPDB 279 1e-75 1KIG-H nrPDB 278 1e-75 2CGA-A nrPDB 278 1e-75 5C67-A nrPDB 278 1e-75 3W94-A nrPDB 278 2e-75 4DUR-A nrPDB 277 3e-75 4MPW-A nrPDB 276 7e-75 1FXY-A nrPDB 276 8e-75 4DGJ-A nrPDB 275 1e-74 1X7A-C nrPDB 275 2e-74 3LC3-A nrPDB 275 2e-74 3K65-B nrPDB 275 2e-74 1LTO-A nrPDB 274 3e-74 1P57-B nrPDB 274 3e-74 1MKW-K nrPDB 274 3e-74 3NXP-A nrPDB 274 4e-74 4KKD-A nrPDB 273 5e-74 3P8G-A nrPDB 272 1e-73 1C5M-D nrPDB 272 1e-73 1EKB-B nrPDB 272 2e-73 1ELV-A nrPDB 271 2e-73 4NZQ-A nrPDB 271 2e-73 6AOD-C nrPDB 271 2e-73 4IGD-A nrPDB 269 7e-73 1EUF-A nrPDB 269 1e-72 2OQ5-A nrPDB 268 1e-72 2TLD-E nrPDB 267 2e-72 1BDA-A nrPDB 267 4e-72 2OCV-B nrPDB 267 5e-72 1VR1-H nrPDB 266 6e-72 1SGF-G nrPDB 266 7e-72 4J1Y-A nrPDB 265 2e-71 1ETT-H nrPDB 264 2e-71 3G01-A nrPDB 264 3e-71 1YC0-A nrPDB 263 5e-71 1A5I-A nrPDB 263 6e-71 3E0N-B nrPDB 262 9e-71 3DFJ-A nrPDB 262 9e-71 2F91-A nrPDB 261 2e-70 2EEK-A nrPDB 261 3e-70 1NPM-A nrPDB 260 4e-70 1NN6-A nrPDB 260 6e-70 4NFE-A nrPDB 259 8e-70 5MS3-A nrPDB 258 2e-69 1IAU-A nrPDB 258 2e-69 1FIZ-A nrPDB 258 2e-69 1SC8-U nrPDB 257 3e-69 1FIW-A nrPDB 256 9e-69 2PSX-A nrPDB 255 1e-68 1FDP-A nrPDB 255 2e-68 3F6U-H nrPDB 254 3e-68 1SPJ-A nrPDB 254 4e-68 1Q3X-A nrPDB 252 1e-67 3TK9-A nrPDB 252 2e-67 6QHB-A nrPDB 252 2e-67 4Z6A-H nrPDB 251 2e-67 1GPZ-A nrPDB 251 3e-67 2R0L-A nrPDB 251 3e-67 1MD7-A nrPDB 250 3e-67 5TO3-B nrPDB 250 4e-67 4IW4-E nrPDB 250 5e-67 3QUM-P nrPDB 250 6e-67 5UBM-A nrPDB 249 1e-66 1ZJK-A nrPDB 248 2e-66 5LHN-A nrPDB 247 3e-66 5FCR-A nrPDB 247 3e-66 1AO5-A nrPDB 247 3e-66 2XRC-A nrPDB 247 4e-66 1ORF-A nrPDB 246 6e-66 1TON-A nrPDB 245 2e-65 3RP2-A nrPDB 244 4e-65 3BSQ-A nrPDB 243 5e-65 4XDE-A nrPDB 242 9e-65 4E7N-A nrPDB 242 1e-64 4GSO-A nrPDB 242 1e-64 2OLG-A nrPDB 241 2e-64 3S9B-A nrPDB 241 2e-64 4BXW-A nrPDB 241 3e-64 4DJZ-B nrPDB 239 1e-63 1SGF-A nrPDB 239 1e-63 5ZFH-A nrPDB 239 1e-63 1MZD-A nrPDB 239 1e-63 1FUJ-A nrPDB 238 2e-63 2XXL-A nrPDB 237 3e-63 2AIQ-A nrPDB 236 8e-63 2ZKS-A nrPDB 235 2e-62 5O32-I nrPDB 234 3e-62 2RDL-A nrPDB 234 4e-62 2BDH-A nrPDB 233 4e-62 4FXG-H nrPDB 233 7e-62 1KYN-A nrPDB 233 7e-62 1GVZ-A nrPDB 232 1e-61 4Q7Y-A nrPDB 231 2e-61 1AZZ-A nrPDB 230 3e-61 1OP0-A nrPDB 229 1e-60 2B9L-A nrPDB 228 3e-60 2QY0-B nrPDB 227 5e-60 1BQY-A nrPDB 226 1e-59 1YM0-A nrPDB 224 3e-59 6BQM-A nrPDB 223 8e-59 3S69-A nrPDB 222 2e-58 5LPF-A nrPDB 220 6e-58 1EQ9-A nrPDB 218 2e-57 2HLC-A nrPDB 216 8e-57 4LK4-A nrPDB 215 1e-56 3I77-A nrPDB 214 3e-56 4WJG-C nrPDB 213 5e-56 5XRF-A nrPDB 212 1e-55 4F4O-C nrPDB 210 4e-55 2ASU-B nrPDB 208 3e-54 5KWM-A nrPDB 207 5e-54 3BEU-A nrPDB 206 6e-54 4X0L-C nrPDB 204 3e-53 1AE5-A nrPDB 203 4e-53 1PPF-E nrPDB 200 6e-52 1PQ7-A nrPDB 200 8e-52 2FMJ-A nrPDB 198 1e-51 1SI5-H nrPDB 197 5e-51 1M9U-A nrPDB 194 3e-50 3H7O-A nrPDB 188 2e-48 5XW8-A nrPDB 172 1e-43 2PKA-B nrPDB 167 4e-42 3VGC-B nrPDB 161 2e-40 2JET-B nrPDB 161 3e-40 2WIN-I nrPDB 160 5e-40 1RIW-B nrPDB 160 7e-40 3H7T-A nrPDB 157 4e-39 1DLE-A nrPDB 157 4e-39 1BBR-H nrPDB 156 8e-39 2OK5-A nrPDB 156 1e-38 3F1S-B nrPDB 148 2e-36 2I6S-A nrPDB 146 8e-36 3H5C-B nrPDB 145 2e-35 1AKS-B nrPDB 124 5e-29 2HNT-F nrPDB 119 1e-27 1BBR-E nrPDB 118 3e-27 3RU4-E nrPDB 112 1e-25 2JET-C nrPDB 109 1e-24 2KAI-A nrPDB 106 1e-23 1EPT-B nrPDB 99 9e-22 2HNT-E nrPDB 81 3e-16 Sequences not found previously or not previously below threshold: 2HNT-C nrPDB 81 7e-16 1P3E-A nrPDB 41 5e-04 4JCN-A nrPDB 33 0.12 2QY0-A nrPDB 33 0.12 3MH6-A nrPDB 31 0.43 5ILB-A nrPDB 31 0.43 4FLN-A nrPDB 31 0.43 1DUE-A nrPDB 31 0.47 3H7V-A nrPDB 31 0.61 3SZE-A nrPDB 31 0.69 3LT3-A nrPDB 31 0.81 4NCX-A nrPDB 30 1.0 2WMN-A nrPDB 30 1.1 5XIP-A nrPDB 30 1.1 5UBM-B nrPDB 30 1.4 5JYK-A nrPDB 29 1.5 4XZB-A nrPDB 29 1.6 5ILA-A nrPDB 29 2.5 5XIG-A nrPDB 29 2.6 2CTL-A nrPDB 29 2.6 3AK5-A nrPDB 28 4.5 2JIH-A nrPDB 28 4.8 2PFE-A nrPDB 28 5.1 >4H4F-A nrPDB Length = 249 Score = 357 bits (917), Expect = 3e-99, Method: Composition-based stats. Identities = 239/239 (100%), Positives = 239/239 (100%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 180 Query: 210 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL Sbjct: 181 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 239 >1PYT-D nrPDB Length = 251 Score = 344 bits (882), Expect = 3e-95, Method: Composition-based stats. Identities = 202/252 (80%), Positives = 224/252 (88%), Gaps = 1/252 (0%) Query: 17 CGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI 76 CG P F PNLSARVVGGEDA PHSWPWQISLQYL+++TWRHTCGGTLI N VLTAAHCI Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 77 SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDT 136 SNT TYRVA+GKNNLEVEDE GSL+VGVDTI VH++WN+ L+RNDIALIKLAE VEL DT Sbjct: 61 SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDT 120 Query: 137 IQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 IQVACLP + SLLP+DYPC+VTGWGRL+TNGPIA +LQQGLQPVVD+ATCS+ DWWG V Sbjct: 121 IQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTV 180 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 K+TMVCAGGDGVISACNGDSGGPLNCQ +G W+V GIVSFGS CNT KKP V+TRVS Sbjct: 181 KETMVCAGGDGVISACNGDSGGPLNCQ-ADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVS 239 Query: 257 AYIDWINEKMQL 268 AYIDWIN+K+QL Sbjct: 240 AYIDWINQKLQL 251 >1BRU-P nrPDB Length = 241 Score = 321 bits (824), Expect = 1e-88, Method: Composition-based stats. Identities = 150/239 (62%), Positives = 180/239 (75%), Gaps = 3/239 (1%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGGEDARP+SWPWQ+SLQY + WRHTCGGTL+ ++VLTAAHCIS++RTYRV +G++ Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLL--RNDIALIKLAEHVELSDTIQVACLPEKDS 147 +L +E GSL V V + VH+ WN+ L NDIAL+KLA V L+D IQ+ CLP + Sbjct: 61 SLST-NEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGT 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +LP +Y CYVTGWGRL TNG D LQQG VVD+ATCS+ WWG VK M+CAGGDG Sbjct: 120 ILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDG 179 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +IS+CNGDSGGPLNCQ NG W+V GIVSFGS GCN KP V+TRVS YIDWIN + Sbjct: 180 IISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVI 238 >3T2N-A nrPDB Length = 372 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 97/272 (35%), Positives = 137/272 (50%), Gaps = 26/272 (9%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L A CG P + R+VGG D WPWQ+SL+Y H CGG+L++ ++V Sbjct: 101 LAAICQDCGRRKLPVD---RIVGGRDTSLGRWPWQVSLRYD----GAHLCGGSLLSGDWV 153 Query: 70 LTAAHCISNTRT----YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW------NALLLR 119 LTAAHC +RV G + L +GV + H + N+ Sbjct: 154 LTAAHCFPERNRVLSRWRVFAGA---VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS 210 Query: 120 NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQP 179 NDIAL+ L+ + L++ IQ CLP L C VTGWG G A LQ+ P Sbjct: 211 NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVP 270 Query: 180 VVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQL---ENGSWEVFGIV 235 ++ + C+ D++G ++K M CAG +G I AC GDSGGP C+ W + GIV Sbjct: 271 IISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIV 330 Query: 236 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 S+G GC +KP VYT+VS + +WI + ++ Sbjct: 331 SWG--TGCALAQKPGVYTKVSDFREWIFQAIK 360 >1F7Z-A nrPDB Length = 233 Score = 291 bits (745), Expect = 2e-79, Method: Composition-based stats. Identities = 85/248 (34%), Positives = 128/248 (51%), Gaps = 21/248 (8%) Query: 21 SFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR 80 +FP + +VGG + +S P+Q+SL ++ H CGG+LI +V++AAHC + Sbjct: 2 AFPVDDDDAIVGGYTCQENSVPYQVSL-----NSGYHFCGGSLINDQWVVSAAHCYKSR- 55 Query: 81 TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140 +V +G++N+ V E FV I H ++ L NDI LIKL+ V+L+ + Sbjct: 56 -IQVRLGEHNINVL-EGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATV 113 Query: 141 CLPEKDSLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKT 199 LP S P C ++GWG ++G D LQ P++ A C + ++ Sbjct: 114 ALPS--SCAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEAS--YPGKITDN 169 Query: 200 MVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAY 258 MVC G +G +C GDSGGP+ C E + GIVS+G GC P VYT+V Y Sbjct: 170 MVCVGFLEGGKDSCQGDSGGPVVCNGE-----LQGIVSWG--YGCALPDNPGVYTKVCNY 222 Query: 259 IDWINEKM 266 +DWI + + Sbjct: 223 VDWIQDTI 230 >2V35-A nrPDB Length = 240 Score = 291 bits (745), Expect = 2e-79, Method: Composition-based stats. Identities = 125/239 (52%), Positives = 160/239 (66%), Gaps = 4/239 (1%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG +A+ +SWP QISLQY +W HTCGGTLI N+V+TAAHC+ T+RV VG++ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLL--RNDIALIKLAEHVELSDTIQVACLPEKDS 147 NL +++ +VGV I VH WN + DIAL++LA+ V L+ +Q+ LP + Sbjct: 61 NLN-QNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGT 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +L + PCY+TGWG TNG +A LQQ P VD+A CS +WG VK +MVCAGGDG Sbjct: 120 ILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDG 179 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 V S C GDSGGPL+C L NG + V G+ SF SR GCN +KP V+TRVSAYI WIN + Sbjct: 180 VRSGCQGDSGGPLHC-LVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 >5FXL-A nrPDB Length = 246 Score = 289 bits (740), Expect = 9e-79, Method: Composition-based stats. Identities = 82/248 (33%), Positives = 130/248 (52%), Gaps = 21/248 (8%) Query: 21 SFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR 80 +FP + ++VGG ++ P+Q+SL ++ H CGG+LI S +V++AAHC + Sbjct: 15 AFPVDDDDKIVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKSG- 68 Query: 81 TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140 +V +G++N+ V E F+ VH +N+ L NDI LIKL L+ + Sbjct: 69 -IQVRLGEDNINVV-EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASI 126 Query: 141 CLPEKDSLLPKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKT 199 LP S C ++GWG ++G D L+ P++ ++C + ++ Sbjct: 127 SLPT--SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA--YPGQITSN 182 Query: 200 MVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAY 258 M CAG +G +C GDSGGP+ C S ++ GIVS+GS GC + KP VYT+V Y Sbjct: 183 MFCAGYLEGGKDSCQGDSGGPVVC-----SGKLQGIVSWGS--GCAQKNKPGVYTKVCNY 235 Query: 259 IDWINEKM 266 + WI + + Sbjct: 236 VSWIKQTI 243 >4AN7-A nrPDB Length = 231 Score = 289 bits (740), Expect = 9e-79, Method: Composition-based stats. Identities = 81/247 (32%), Positives = 128/247 (51%), Gaps = 21/247 (8%) Query: 22 FPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT 81 FP + ++VGG +S P+Q+SL ++ H CGG+LI S +V++AAHC + Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKSR-- 53 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +V +G++N++V E F+ I H +N L NDI LIKL+ L+ + Sbjct: 54 IQVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 112 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTM 200 LP S C ++GWG ++G LQ PV+ ++C + ++ M Sbjct: 113 LPR--SCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSS--YPGQITGNM 168 Query: 201 VCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYI 259 +C G +G +C GDSGGP+ C ++ GIVS+G GC + KP VYT+V Y+ Sbjct: 169 ICVGFLEGGKDSCQGDSGGPVVCN-----GQLQGIVSWG--YGCAQKNKPGVYTKVCNYV 221 Query: 260 DWINEKM 266 +WI + + Sbjct: 222 NWIQQTI 228 >5TJX-A nrPDB Length = 263 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 95/247 (38%), Positives = 135/247 (54%), Gaps = 10/247 (4%) Query: 25 NLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRT 81 S R+VGG ++ WPWQ+SLQ +K RH CGG+LI +VLTAAHC Sbjct: 11 KTSTRIVGGTESSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 69 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +R+ G L ++ F + I +H+ + +DIALIKL +E ++ + Sbjct: 70 WRIYSGILELSDITKDTP-FSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPIS 128 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 LP K C+VTGWG G I + LQ+ P+V + C + + +++ + MV Sbjct: 129 LPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMV 187 Query: 202 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 CAG +G AC GDSGGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+D Sbjct: 188 CAGYKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMD 244 Query: 261 WINEKMQ 267 WI EK Q Sbjct: 245 WILEKTQ 251 >6I44-A nrPDB Length = 627 Score = 287 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 94/247 (38%), Positives = 135/247 (54%), Gaps = 10/247 (4%) Query: 25 NLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRT 81 S R+VGG + WPWQ+SLQ +K RH CGG+LI +VLTAAHC Sbjct: 375 KTSTRIVGGTQSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 433 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +R+ G L ++ F + I +H+ + +DIALIKL ++ ++ + C Sbjct: 434 WRIYSGILQLSDITKDTP-FSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPIC 492 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 LP K C+VTGWG G I + LQ+ P+V + C + + +++ + MV Sbjct: 493 LPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMV 551 Query: 202 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 CAG +G AC GD+GGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+D Sbjct: 552 CAGYKEGGKDACKGDAGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMD 608 Query: 261 WINEKMQ 267 WI EK Q Sbjct: 609 WILEKTQ 615 >1FON-A nrPDB Length = 240 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 129/238 (54%), Positives = 167/238 (70%), Gaps = 4/238 (1%) Query: 32 GGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNL 91 GEDA P+SW WQ+SLQY K+ + HTCGG+LIA ++V+TA HCIS +RTY+V +G+ + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 92 EVEDEEGSLF-VGVDTIHVHKRWNAL--LLRNDIALIKLAEHVELSDTIQVACLPEKDSL 148 V + + + + VH WN+ NDIAL+KL+ +L D +Q+A LP + Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 149 LPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 LP + PCY++GWGRL+T GP+ DKLQQ L P VD+ CS+ DWWG VKKTMVCAGGD Sbjct: 121 LPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT- 179 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S CNGDSGGPLNC +GSW+V G+ SF S GCNT KKP V+TRVSA+IDWI+E + Sbjct: 180 RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 >1UTJ-A nrPDB Length = 242 Score = 286 bits (733), Expect = 5e-78, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 128/244 (52%), Gaps = 20/244 (8%) Query: 24 PNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR 83 ++VGG + +P+S P Q+SL ++ H CGG+L+ N+V++AAHC + Sbjct: 15 ATEDDKIVGGYECKPYSQPHQVSL-----NSGYHFCGGSLVNENWVVSAAHCYKSR--VE 67 Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP 143 V +G++N++V E F+ + H +++ + NDI LIKL++ L+ +Q LP Sbjct: 68 VRLGEHNIKVT-EGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALP 126 Query: 144 EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 203 S P C V+GWG ++ ++KLQ P++ ++ C+ + + + M CA Sbjct: 127 T--SCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCN--NSYPGMITNAMFCA 182 Query: 204 GG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 G +G +C GDSGGP+ C E + G+VS+G GC P VY +V + DW+ Sbjct: 183 GYLEGGKDSCQGDSGGPVVCNGE-----LQGVVSWG--YGCAEPGNPGVYAKVCIFNDWL 235 Query: 263 NEKM 266 M Sbjct: 236 TSTM 239 >1ELT-A nrPDB Length = 236 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 125/239 (52%), Positives = 164/239 (68%), Gaps = 5/239 (2%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG A+P+SWPWQISLQY ++ HTCGG+LI +V+TAAHC+ + RT+RV +G++ Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLL--RNDIALIKLAEHVELSDTIQVACLPEKDS 147 NL +E + V+++ +H WN+ + DIAL++L L+ +Q+A LP + Sbjct: 61 NLNT-NEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQ 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +LP + PCY+TGWG+ T GP++D L+Q P VDHATCS WWG VK TMVCAGG G Sbjct: 120 ILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG-G 178 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S CNGDSGGPLNCQ+ NGS+ V G+ SF S GCN KKP V+TRVSAYI W+N M Sbjct: 179 ANSGCNGDSGGPLNCQV-NGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >2F83-A nrPDB Length = 625 Score = 283 bits (725), Expect = 5e-77, Method: Composition-based stats. Identities = 94/247 (38%), Positives = 134/247 (54%), Gaps = 10/247 (4%) Query: 25 NLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI---SNTRT 81 + R+VGG + WPWQ++L + + T RH CGG++I + ++LTAAHC + + Sbjct: 383 KIKPRIVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI 441 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 RV G N E+ S F GV I +H ++ DIAL+KL V +D+ + C Sbjct: 442 LRVYSGILNQSEIKEDTS-FFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPIC 500 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 LP K C+VTGWG I + LQ+ P+V + C + + G ++ M+ Sbjct: 501 LPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHKMI 559 Query: 202 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 CAG +G AC GDSGGPL+C+ N W + GI S+G GC R++P VYT V Y+D Sbjct: 560 CAGYREGGKDACKGDSGGPLSCK-HNEVWHLVGITSWG--EGCAQRERPGVYTNVVEYVD 616 Query: 261 WINEKMQ 267 WI EK Q Sbjct: 617 WILEKTQ 623 >5GVT-A nrPDB Length = 250 Score = 283 bits (725), Expect = 5e-77, Method: Composition-based stats. Identities = 88/242 (36%), Positives = 129/242 (53%), Gaps = 10/242 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRTYRVAV 86 +VGG +A WPWQ+SLQ +K + H CGG++I +VLTAAHC +R+ Sbjct: 1 IVGGTNASLGEWPWQVSLQ-VKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYG 59 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G +L +E + + +H+ + DIALIKL + ++ + LP K Sbjct: 60 GILSLSEITKETPS-SRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKA 118 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG- 205 C+VTGWG G + LQ+ P+V + C + + + + K M+CAG Sbjct: 119 DTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQK-KYRDYVINKQMICAGYK 177 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 +G AC GDSGGPL C+ +G W++ GI S+G GC + +P VYT+VS Y+DWI EK Sbjct: 178 EGGTDACKGDSGGPLVCK-HSGRWQLVGITSWG--EGCARKDQPGVYTKVSEYMDWILEK 234 Query: 266 MQ 267 Q Sbjct: 235 TQ 236 >4WWY-A nrPDB Length = 224 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 75/239 (31%), Positives = 120/239 (50%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + +S P+Q+SL ++ H CGG+LI +V++A HC + +V +G++ Sbjct: 1 IVGGYNCEENSVPYQVSL-----NSGYHFCGGSLINEQWVVSAGHCYKSR--IQVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+EV E F+ I H +++ L NDI LIKL+ ++ + LP Sbjct: 54 NIEVL-EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAP--P 110 Query: 150 PKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 C ++GWG ++G D+LQ PV+ A C + ++ M C G +G Sbjct: 111 ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS--YPGKITSNMFCVGFLEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C DSGGP+ C ++ G+VS+G GC + KP VYT+V Y+ WI + Sbjct: 169 GKDSCQRDSGGPVVCN-----GQLQGVVSWGD--GCAQKNKPGVYTKVYNYVKWIKNTI 220 >1FI8-A nrPDB Length = 228 Score = 280 bits (716), Expect = 6e-76, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 121/239 (50%), Gaps = 14/239 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ LQ + + CGG LI +FVLTAAHC + +V +G + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC--SGSKIQVTLGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E E+ + V I H +N+ + NDI L+KL + S ++ LP ++ + Sbjct: 59 NIK-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKV 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 CYV GWG+L G +D LQ+ V + C + K +CAG + Sbjct: 118 KPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCES-YLKNYFDKANEICAGDPKIK 176 Query: 210 -SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 ++ GDSGGPL C+ GIVS+G G P +T+VS ++ WI + M+ Sbjct: 177 RASFRGDSGGPLVCKK-----VAAGIVSYGQNDG----STPRAFTKVSTFLSWIKKTMK 226 >1A0J-A nrPDB Length = 223 Score = 279 bits (715), Expect = 7e-76, Method: Composition-based stats. Identities = 81/239 (33%), Positives = 128/239 (53%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + R +S +Q SLQ + H CGG+LI+S +V++AAHC + +V +G++ Sbjct: 1 IVGGYECRKNSASYQASLQ-----SGYHFCGGSLISSTWVVSAAHCYKSR--IQVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ V +E F+ + +H +N+ L NDI LIKL++ L+ + LP S Sbjct: 54 NIAV-NEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPS--SCA 110 Query: 150 PKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 C V+GWG L ++ D L+ P++ ++C+ + ++ M CAG +G Sbjct: 111 SSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSA--YPGQITSNMFCAGFMEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C ++ G+VS+G GC R KP VYT+V Y WI+ M Sbjct: 169 GKDSCQGDSGGPVVCN-----GQLQGVVSWG--YGCAQRNKPGVYTKVCNYRSWISSTM 220 >5UGG-A nrPDB Length = 251 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 95/262 (36%), Positives = 139/262 (53%), Gaps = 19/262 (7%) Query: 11 LACASSCGVPSF-PPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 A + CG P P RVVGG A PHSWPWQ+SL+ H CGGTLI+ +V Sbjct: 2 FAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTR---FGMHFCGGTLISPEWV 58 Query: 70 LTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126 LTAAHC+ + +Y+V +G + EV E + V + + R DIAL+K Sbjct: 59 LTAAHCLEKSPRPSSYKVILGAH-QEVNLEPHVQEIEVSRLFLEPT------RKDIALLK 111 Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATC 186 L+ ++D + ACLP + ++ C++TGWG A L++ PV+++ C Sbjct: 112 LSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVC 170 Query: 187 SRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 245 +R ++ RV+ T +CAG G +C GDSGGPL C ++ + + G+ S+G GC Sbjct: 171 NRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKD-KYILQGVTSWG--LGCAR 227 Query: 246 RKKPVVYTRVSAYIDWINEKMQ 267 KP VY RVS ++ WI M+ Sbjct: 228 PNKPGVYVRVSRFVTWIEGVMR 249 >1KIG-H nrPDB Length = 241 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 82/242 (33%), Positives = 123/242 (50%), Gaps = 13/242 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG D PWQ L +N+ CGGT++ +VLTAAHC+ + + V VG Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG---FCGGTILNEFYVLTAAHCLHQAKRFTVRVGDR 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD--- 146 N E ++E + V+ H R+ DIA+++L + + ACLPEKD Sbjct: 58 NTE-QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAE 116 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 + L V+G+GR G ++ L+ P VD +TC + + M CAG D Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSF--TITPNMFCAGYD 174 Query: 207 GV-ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 AC GDSGGP + ++ ++ V GIVS+G GC + K VYT+VS ++ WI++ Sbjct: 175 TQPEDACQGDSGGPHVTRFKD-TYFVTGIVSWG--EGCARKGKFGVYTKVSNFLKWIDKI 231 Query: 266 MQ 267 M+ Sbjct: 232 MK 233 >2CGA-A nrPDB Length = 245 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 102/253 (40%), Positives = 144/253 (56%), Gaps = 14/253 (5%) Query: 17 CGVPSFPPNLSA--RVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAH 74 CGVP+ P LS R+V GE+A P SWPWQ+SLQ + T H CGG+LI N+V+TAAH Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAH 57 Query: 75 CISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELS 134 C T V V + E + + + + ++N+L + NDI L+KL+ S Sbjct: 58 C--GVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS 115 Query: 135 DTIQVACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWG 193 T+ CLP C TGWG TN D+LQQ P++ + C + +WG Sbjct: 116 QTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKK--YWG 173 Query: 194 FRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYT 253 ++K M+CAG GV S+C GDSGGPL C+ +NG+W + GIVS+GS C+T P VY Sbjct: 174 TKIKDAMICAGASGV-SSCMGDSGGPLVCK-KNGAWTLVGIVSWGSST-CSTS-TPGVYA 229 Query: 254 RVSAYIDWINEKM 266 RV+A ++W+ + + Sbjct: 230 RVTALVNWVQQTL 242 >5C67-A nrPDB Length = 224 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 122/239 (51%), Gaps = 21/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +S P+Q+SL ++ H CGG+LI+ +V++AAHC +V +G++ Sbjct: 1 IVGGYTCEENSLPYQVSL-----NSGSHFCGGSLISEQWVVSAAHCYKTR--IQVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++V E F+ I H ++N L NDI LIKL+ ++ + LP Sbjct: 54 NIKVL-EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAP--P 110 Query: 150 PKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 C ++GWG + G D+L+ PV+ A C + ++ +M C G +G Sbjct: 111 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS--YPGKITNSMFCVGFLEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C D+GGP+ C ++ G+VS+G GC + +P VYT+V Y+DWI + + Sbjct: 169 GKDSCQRDAGGPVVCN-----GQLQGVVSWGH--GCAWKNRPGVYTKVYNYVDWIKDTI 220 >3W94-A nrPDB Length = 235 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 84/241 (34%), Positives = 126/241 (52%), Gaps = 13/241 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT----YRVA 85 VVGG +A +WPW +SL + RH CG +LI +++LTAAHC+ T + Sbjct: 1 VVGGVNAEKGAWPWMVSLHWR----GRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAV 56 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 +G + + + VD I ++K +N DIA++ L + V ++ + CL + Sbjct: 57 LGLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASE 116 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 D P C++ GWGR G + D LQ+ P+VD C R+ + +M+CAG Sbjct: 117 DQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRL-LPEYTFTSSMLCAGY 175 Query: 206 -DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G + +C GDSGGPL C LE+ W + G+ SFG GC ++P Y RVSA+ WI E Sbjct: 176 PEGGVDSCQGDSGGPLMC-LEDARWTLIGVTSFGV--GCGRPERPGAYARVSAFTSWIAE 232 Query: 265 K 265 Sbjct: 233 T 233 >4DUR-A nrPDB Length = 791 Score = 277 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 95/262 (36%), Positives = 139/262 (53%), Gaps = 19/262 (7%) Query: 11 LACASSCGVPSF-PPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 A + CG P P RVVGG A PHSWPWQ+SL+ H CGGTLI+ +V Sbjct: 542 AAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTR---FGMHFCGGTLISPEWV 598 Query: 70 LTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126 LTAAHC+ + +Y+V +G + EV E + V + + R DIAL+K Sbjct: 599 LTAAHCLEKSPRPSSYKVILGAH-QEVNLEPHVQEIEVSRLFLEPT------RKDIALLK 651 Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATC 186 L+ ++D + ACLP + ++ C++TGWG A L++ PV+++ C Sbjct: 652 LSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVC 710 Query: 187 SRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 245 +R ++ RV+ T +CAG G +C GDSGGPL C ++ + + G+ S+G GC Sbjct: 711 NRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKD-KYILQGVTSWG--LGCAR 767 Query: 246 RKKPVVYTRVSAYIDWINEKMQ 267 KP VY RVS ++ WI M+ Sbjct: 768 PNKPGVYVRVSRFVTWIEGVMR 789 >4MPW-A nrPDB Length = 245 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 87/247 (35%), Positives = 132/247 (53%), Gaps = 22/247 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----SNTRTYRVA 85 +VGG++A WPWQ+SL+ + W H CGG+LI +VLTAAHC+ + RV Sbjct: 1 IVGGQEAPRSKWPWQVSLR-VHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 59 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 + + +L +D + V I VH ++ + DIAL++L E V++S + LP Sbjct: 60 LREQHLYYQD----QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPA 115 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIAD--KLQQGLQPVVDHATCSRIDWWGFR-------V 196 P PC+VTGWG + + + L+Q P++++ C G V Sbjct: 116 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 175 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + M+CAG +C GDSGGPL C++ NG+W G+VS+G GC +P +YTRV+ Sbjct: 176 RDDMLCAGNTR-RDSCQGDSGGPLVCKV-NGTWLQAGVVSWG--EGCAQPNRPGIYTRVT 231 Query: 257 AYIDWIN 263 Y+DWI+ Sbjct: 232 YYLDWIH 238 >1FXY-A nrPDB Length = 228 Score = 276 bits (706), Expect = 8e-75, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 118/239 (49%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + + PWQ L +N+ CGGT+++ ++LTAAHC+ + ++V VG Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEG---FCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N E ++E G V+ + H R+ DIA+++L + + A LP Sbjct: 58 NTE-QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAP--P 114 Query: 150 PKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DG 207 C ++GWG ++G D+LQ PV+ A C + ++ M C G +G Sbjct: 115 ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS--YPGKITSNMFCVGFLEG 172 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C ++ G+VS+G GC + KP VYT+V Y+ WI + Sbjct: 173 GKDSCQGDSGGPVVCN-----GQLQGVVSWGD--GCAQKNKPGVYTKVYNYVKWIKNTI 224 >4DGJ-A nrPDB Length = 235 Score = 275 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 79/243 (32%), Positives = 126/243 (51%), Gaps = 13/243 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR----TYRVA 85 +VGG DA+ +WPW + L Y R CG +L++S+++++AAHC+ + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDD----RLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 56 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 +G + ++ +D I ++ +N NDIA++ L V +D IQ LPE+ Sbjct: 57 LGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEE 116 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 + + P C + GWG + G AD LQ+ P++ + C + + + + M+CAG Sbjct: 117 NQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQ-QMPEYNITENMICAGY 175 Query: 206 -DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G I +C GDSGGPL CQ EN W + G+ SFG C +P VY RVS + +WI Sbjct: 176 EEGGIDSCQGDSGGPLMCQ-ENNRWFLAGVTSFGYE--CALPNRPGVYARVSRFTEWIQS 232 Query: 265 KMQ 267 + Sbjct: 233 FLH 235 >1X7A-C nrPDB Length = 235 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 90/244 (36%), Positives = 130/244 (53%), Gaps = 15/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGGE+A+P +PWQ+ L N CGG++I +V+TAAHCI V G+ Sbjct: 1 IVGGENAKPGQFPWQVLL----NGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEY 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALL--LRNDIALIKLAEHVELSDTIQVACLPEKDS 147 N E E E V H +NA + +DIAL++L E + L+ + C+ +K+ Sbjct: 57 NTE-ETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEY 115 Query: 148 L--LPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 K YV+GWGR++ G A LQ P+VD ATC R F + M CAG Sbjct: 116 TNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRST--KFTIYSNMFCAGF 173 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G +C GDSGGP ++E G+ + GI+S+G C + K +YT+VS Y++WI E Sbjct: 174 HEGGKDSCQGDSGGPHVTEVE-GTSFLTGIISWGEE--CAVKGKYGIYTKVSRYVNWIKE 230 Query: 265 KMQL 268 K +L Sbjct: 231 KTKL 234 >3LC3-A nrPDB Length = 235 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 90/244 (36%), Positives = 133/244 (54%), Gaps = 15/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGGEDA+P +PWQ+ L N CGG+++ +++TAAHC+ V G++ Sbjct: 1 VVGGEDAKPGQFPWQVVL----NGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALL--LRNDIALIKLAEHVELSDTIQVACLPEKDS 147 N+E E E V I H +NA + +DIAL++L E + L+ + C+ +K+ Sbjct: 57 NIE-ETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 115 Query: 148 L--LPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204 K YV+GWGR++ G A LQ P+VD ATC R F + M CAG Sbjct: 116 TNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRST--KFTIYNNMFCAGF 173 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 +G +C GDSGGP ++E G+ + GI+S+G C + K +YT+VS Y++WI E Sbjct: 174 HEGGRDSCQGDSGGPHVTEVE-GTSFLTGIISWGEE--CAMKGKYGIYTKVSRYVNWIKE 230 Query: 265 KMQL 268 K +L Sbjct: 231 KTKL 234 >3K65-B nrPDB Length = 308 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 85/264 (32%), Positives = 117/264 (44%), Gaps = 29/264 (10%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------S 77 + R+V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 46 IDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 103 Query: 78 NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDT 136 V +GK++ + ++ I++H R+N L DIAL+KL + V SD Sbjct: 104 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 163 Query: 137 IQVACLPEKD---SLLPKDYPCYVTGWGRLWTNGP------IADKLQQGLQPVVDHATCS 187 I CLP+++ SLL Y VTGWG L LQ P+V+ C Sbjct: 164 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 223 Query: 188 RIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRG 242 D R+ M CAG +G AC GD+GGP + N W GIVS+G G Sbjct: 224 --DSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWG--EG 279 Query: 243 CNTRKKPVVYTRVSAYIDWINEKM 266 C+ K YT V WI + + Sbjct: 280 CDRDGKYGFYTHVFRLKKWIQKVI 303 >1LTO-A nrPDB Length = 245 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 87/247 (35%), Positives = 135/247 (54%), Gaps = 22/247 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC----ISNTRTYRVA 85 +VGG++A WPWQ+SL+ +++ W H CGG+LI +VLTAAHC + + T RV Sbjct: 1 IVGGQEAPRSKWPWQVSLR-VRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQ 59 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 + + +L +D + V I VH ++ + DIAL++L E V +S + LP Sbjct: 60 LREQHLYYQD----QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPA 115 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIAD--KLQQGLQPVVDHATCSRIDWWGFR-------V 196 P PC+VTGWG + + P+ L+Q P++++ C G + Sbjct: 116 SETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRII 175 Query: 197 KKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + M+CAG + +C GDSGGPL C++ NG+W G+VS+ GC +P +YTRV+ Sbjct: 176 RDDMLCAG-NSQRDSCKGDSGGPLVCKV-NGTWLQAGVVSW--DEGCAQPNRPGIYTRVT 231 Query: 257 AYIDWIN 263 Y+DWI+ Sbjct: 232 YYLDWIH 238 >1P57-B nrPDB Length = 255 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 91/252 (36%), Positives = 130/252 (51%), Gaps = 23/252 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT----YRVA 85 +VGG D WPWQ+SL+Y H CGG+L++ ++VLTAAHC +RV Sbjct: 1 IVGGRDTSLGRWPWQVSLRYD----GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 56 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRW------NALLLRNDIALIKLAEHVELSDTIQV 139 G + L +GV + H + N+ NDIAL+ L+ + L++ IQ Sbjct: 57 AGA---VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 113 Query: 140 ACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKT 199 CLP L C VTGWG G A LQ+ P++ + C+ D++G ++K Sbjct: 114 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 173 Query: 200 MVCAGG-DGVISACNGDSGGPLNCQL---ENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 M CAG +G I AC GDSGGP C+ W + GIVS+G GC +KP VYT+V Sbjct: 174 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG--TGCALAQKPGVYTKV 231 Query: 256 SAYIDWINEKMQ 267 S + +WI + ++ Sbjct: 232 SDFREWIFQAIK 243 >1MKW-K nrPDB Length = 308 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 87/268 (32%), Positives = 119/268 (44%), Gaps = 29/268 (10%) Query: 22 FPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----- 76 F + R+V G+DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 42 FESYIEGRIVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPW 99 Query: 77 ---SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVE 132 V +GK++ + + +D I++H R+N L DIAL+KL +E Sbjct: 100 DKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIE 159 Query: 133 LSDTIQVACLPEKDS---LLPKDYPCYVTGWGR------LWTNGPIADKLQQGLQPVVDH 183 LSD I CLP+K + LL + VTGWG LQ P+V+ Sbjct: 160 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVER 219 Query: 184 ATCSRIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFG 238 C R+ M CAG G+G AC GDSGGP + N W GIVS+G Sbjct: 220 PVCKAST--RIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG 277 Query: 239 SRRGCNTRKKPVVYTRVSAYIDWINEKM 266 GC+ K YT V WI + + Sbjct: 278 --EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >3NXP-A nrPDB Length = 424 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 86/264 (32%), Positives = 117/264 (44%), Gaps = 29/264 (10%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------S 77 + R+V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 162 IDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 219 Query: 78 NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDT 136 V +GK++ + ++ I++H R+N L DIAL+KL + V SD Sbjct: 220 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 279 Query: 137 IQVACLPEKD---SLLPKDYPCYVTGWGRLWTNGP------IADKLQQGLQPVVDHATCS 187 I CLP+++ SLL Y VTGWG L LQ P+V+ C Sbjct: 280 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 339 Query: 188 RIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRG 242 D R+ M CAG +G AC GDSGGP + N W GIVS+G G Sbjct: 340 --DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG--EG 395 Query: 243 CNTRKKPVVYTRVSAYIDWINEKM 266 C+ K YT V WI + + Sbjct: 396 CDRDGKYGFYTHVFRLKKWIQKVI 419 >4KKD-A nrPDB Length = 433 Score = 273 bits (699), Expect = 5e-74, Method: Composition-based stats. Identities = 89/294 (30%), Positives = 137/294 (46%), Gaps = 38/294 (12%) Query: 9 ALLACASSCGVPSFP-PNLSARVVGGEDARPHSWPWQISL-----QYLKNDTWRHTCGGT 62 +L C CG PS P+L R++GG +A P +PWQ + + ND W + G Sbjct: 133 SLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGS--GA 190 Query: 63 LIASNFVLTAAHCISNTRT-----------YRVAVGKNNLEVEDEEGSLFVGVDTIHVHK 111 L++++++LTAAH + + R V +G ++ V D+ G++ + +H Sbjct: 191 LLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHD--VRDKSGAVNSSAARVVLHP 248 Query: 112 RWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYP-CYVTGWGRLWTN---- 166 +N +DIAL++L E V L + CLP + P + V GWG N Sbjct: 249 DFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVD 308 Query: 167 -------GPIADKLQQGLQPVVDHATCS---RIDWWGFRVKKTMVCAGG-DGVISACNGD 215 ++D LQ PVV HA C + V + M CAG +G C GD Sbjct: 309 EIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGD 368 Query: 216 SGGPLNCQLE-NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 SG + + W V G+VS+G C +++ VYT+VS Y+DW+ E+M L Sbjct: 369 SGEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGL 422 >3P8G-A nrPDB Length = 241 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 83/248 (33%), Positives = 120/248 (48%), Gaps = 16/248 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 VVGG DA WPWQ+SL L H CG +LI+ N++++AAHC S+ Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQG---HICGASLISPNWLVSAAHCYIDDRGFRYSDPTQ 57 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 + +G ++ G + I H +N DIAL++L + E S ++ C Sbjct: 58 WTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPIC 117 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 LP+ + P +VTGWG G A LQ+G V+ TC + ++ M+ Sbjct: 118 LPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCE--NLLPQQITPRMM 175 Query: 202 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 C G G + +C GDSGGPL+ +G G+VS+G GC R KP VYTR+ + D Sbjct: 176 CVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD--GCAQRNKPGVYTRLPLFRD 233 Query: 261 WINEKMQL 268 WI E + Sbjct: 234 WIKENTGV 241 >1C5M-D nrPDB Length = 255 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 79/242 (32%), Positives = 128/242 (52%), Gaps = 13/242 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG++ + PWQ L +N+ CGGT+++ ++LTAAHC+ + ++V VG Sbjct: 1 IVGGQECKDGECPWQALLINEENEG---FCGGTILSEFYILTAAHCLYQAKRFKVRVGDR 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD--- 146 N E ++E G V+ + H R+ DIA+++L + + ACLPE+D Sbjct: 58 NTE-QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAE 116 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 S L V+G+GR G + +L+ P VD +C + + + M CAG D Sbjct: 117 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF--IITQNMFCAGYD 174 Query: 207 GVI-SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 AC GDSGGP + ++ ++ V GIVS+G GC + K +YT+V+A++ WI+ Sbjct: 175 TKQEDACQGDSGGPHVTRFKD-TYFVTGIVSWG--EGCARKGKYGIYTKVTAFLKWIDRS 231 Query: 266 MQ 267 M+ Sbjct: 232 MK 233 >1EKB-B nrPDB Length = 235 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 77/243 (31%), Positives = 126/243 (51%), Gaps = 13/243 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR----TYRVA 85 +VGG D+R +WPW ++L + + CG +L++ +++++AAHC+ ++ Sbjct: 1 IVGGSDSREGAWPWVVALYFDD----QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAV 56 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 +G + +D I ++ +N NDIA++ L V +D IQ CLPE+ Sbjct: 57 LGLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEE 116 Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 + + P C + GWG L G AD LQ+ P++ + C + + + + MVCAG Sbjct: 117 NQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQ-QMPEYNITENMVCAGY 175 Query: 206 D-GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 + G + +C GDSGGPL CQ EN W + G+ SFG + C +P VY RV + +WI Sbjct: 176 EAGGVDSCQGDSGGPLMCQ-ENNRWLLAGVTSFGYQ--CALPNRPGVYARVPRFTEWIQS 232 Query: 265 KMQ 267 + Sbjct: 233 FLH 235 >1ELV-A nrPDB Length = 333 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 83/276 (30%), Positives = 123/276 (44%), Gaps = 31/276 (11%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C CGVP P R++GG DA ++PWQ+ ++ W GG LI +V Sbjct: 63 LPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQV----FFDNPWA---GGALINEYWV 115 Query: 70 LTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-------ALLLRNDI 122 LTAAH + R + VG +++ S + + + +H W NDI Sbjct: 116 LTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDI 175 Query: 123 ALIKLAEHVELSDTIQVACLP--EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV 180 AL++L + V++ T+ CLP D L ++GWGR A +L+ PV Sbjct: 176 ALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPV 234 Query: 181 VDHATCSRIDWWG-------FRVKKTMVCAGGDGVISACNGDSGGPLNCQLENG--SWEV 231 C + + M+CAGG+ + +C GDSGG Q N + Sbjct: 235 APLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYA 294 Query: 232 FGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 G+VS+G + C T +YTRV Y+DWI + MQ Sbjct: 295 AGLVSWGPQ--CGT---YGLYTRVKNYVDWIMKTMQ 325 >4NZQ-A nrPDB Length = 557 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 86/264 (32%), Positives = 117/264 (44%), Gaps = 29/264 (10%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------S 77 + R+V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 295 IDGRIVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 352 Query: 78 NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDT 136 V +GK++ + ++ I++H R+N L DIAL+KL + V SD Sbjct: 353 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 412 Query: 137 IQVACLPEKD---SLLPKDYPCYVTGWGRLWTNGP------IADKLQQGLQPVVDHATCS 187 I CLP+++ SLL Y VTGWG L LQ P+V+ C Sbjct: 413 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 472 Query: 188 RIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRG 242 D R+ M CAG +G AC GDSGGP + N W GIVS+G G Sbjct: 473 --DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG--EG 528 Query: 243 CNTRKKPVVYTRVSAYIDWINEKM 266 C+ K YT V WI + + Sbjct: 529 CDRDGKYGFYTHVFRLKKWIQKVI 552 >6AOD-C nrPDB Length = 245 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 90/242 (37%), Positives = 131/242 (54%), Gaps = 10/242 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI---SNTRTYRVAV 86 +VGG + WPWQ++L + + T RH CGG++I + ++LTAAHC + + RV Sbjct: 1 IVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 59 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G E+ S F GV I +H ++ DIAL+KL V+ +D+ + LP K Sbjct: 60 GILQQSEIKEDTS-FFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKG 118 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG- 205 C+VTGWG I + LQ+ P+V + C + + G ++ M+CAG Sbjct: 119 DRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHKMICAGYR 177 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 +G AC GD+GGPL+C+ N W + GI S+G GC R++P VYT V Y+DWI EK Sbjct: 178 EGGKDACKGDAGGPLSCK-HNEVWHLVGITSWG--EGCAQRERPGVYTNVVEYVDWILEK 234 Query: 266 MQ 267 Q Sbjct: 235 TQ 236 >4IGD-A nrPDB Length = 406 Score = 269 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 79/279 (28%), Positives = 132/279 (47%), Gaps = 28/279 (10%) Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 +L C CG+P F L A++ G A+ + PW L +L CGG+L+ S++ Sbjct: 135 SLPTCLPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQP---FCGGSLLGSSW 191 Query: 69 VLTAAHCIS----------------NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKR 112 ++TAAHC+ + +++ +GK+ + +E +GV +H + Sbjct: 192 IVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQ 250 Query: 113 WNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADK 172 ++ ND+AL++L E L+ + CLPE + V+GWG+ + + Sbjct: 251 YDPNTFENDVALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQFLQ-RFPET 307 Query: 173 LQQGLQPVVDHATCSRIDWW-GFRVKKTMVCAGG-DGVISACNGDSGGPLN-CQLENGSW 229 L + P+VDH+TC + +V + M+CAG +G AC GDSGGP+ E G W Sbjct: 308 LMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQW 367 Query: 230 EVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 + G VS+G C + + VY+ + DWI + Sbjct: 368 YLVGTVSWGDD--CGKKDRYGVYSYIHHNKDWIQRVTGV 404 >1EUF-A nrPDB Length = 227 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 82/239 (34%), Positives = 121/239 (50%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ L + + H CGG L+ +FVLTAAHC+ ++ V +G + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGK-SHICGGFLVREDFVLTAAHCLGSS--INVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ +E E + V H +N L NDI L+KL +++D + LP + + Sbjct: 58 NI-MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 208 C V GWGRL N P DKLQ+ V C I + + T +CAG Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKC--IARFKNYIPFTQICAGDPSKR 174 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 ++ +GDSGGPL C GIVS+G G P VYTR+S+++ WI+ M+ Sbjct: 175 KNSFSGDSGGPLVCN-----GVAQGIVSYGRNDG----TTPDVYTRISSFLSWIHSTMR 224 >2OQ5-A nrPDB Length = 232 Score = 268 bits (686), Expect = 1e-72, Method: Composition-based stats. Identities = 78/240 (32%), Positives = 118/240 (49%), Gaps = 9/240 (3%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + WPWQ SLQ+ H CG TLI + ++++AAHC + + A Sbjct: 1 IVGGTEVEEGEWPWQASLQWD----GSHRCGATLINATWLVSAAHCFTTYKNP--ARWTA 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + V + + G+ I VH+++ DI+L +L+ V ++ + CLP+ Sbjct: 55 SFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEF 114 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGV 208 +VTG+G L +G + L+Q ++D TC+ + + M+CAG +G Sbjct: 115 QPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGK 174 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 AC GDSGGPL W + GIVS+G C KP VYTRV+A DWI K + Sbjct: 175 TDACQGDSGGPLVSSDARDIWYLAGIVSWGDE--CAKPNKPGVYTRVTALRDWITSKTGI 232 >2TLD-E nrPDB Length = 220 Score = 267 bits (684), Expect = 2e-72, Method: Composition-based stats. Identities = 80/238 (33%), Positives = 125/238 (52%), Gaps = 22/238 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG ++ P+Q+SL ++ H CGG+LI S +V++AAHC + +V +G++ Sbjct: 1 IVGGYTCGANTVPYQVSL-----NSGYHFCGGSLINSQWVVSAAHCYKSG--IQVRLGED 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ V E F+ VH +N+ L NDI LIKL L+ + LP S Sbjct: 54 NINVV-EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCA 110 Query: 150 PKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 C ++GWG ++G D L+ P++ ++C + ++ M CAG +G Sbjct: 111 SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA--YPGQITSNMFCAGLEGG 168 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C S ++ GIVS+GS GC + KP VYT+V Y+ WI + + Sbjct: 169 -DSCQGDSGGPVVC-----SGKLQGIVSWGS--GCA-KNKPGVYTKVCNYVSWIKQTI 217 >1BDA-A nrPDB Length = 265 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 83/269 (30%), Positives = 130/269 (48%), Gaps = 22/269 (8%) Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISL--QYLKNDTWRHTCGGTLIASNFVLTAA 73 +CG+ + R+ GG A S PWQ ++ ++ ++ R CGG LI+S ++L+AA Sbjct: 1 TCGLRQYS-QPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAA 59 Query: 74 HCISN---TRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH 130 HC V +G+ V EE V+ VHK ++ NDIAL++L Sbjct: 60 HCFQERFPPHHLTVILGRTYRVVPGEE-EQKFEVEKYIVHKEFDDDTYDNDIALLQLKSD 118 Query: 131 ----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHAT 185 + S ++ CLP D LP C ++G+G+ P +++L++ + + Sbjct: 119 SSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSR 178 Query: 186 CSRIDWWGFRVKKTMVCAGGDGV-------ISACNGDSGGPLNCQLENGSWEVFGIVSFG 238 C+ V M+CAG AC GDSGGPL C L +G + GI+S+G Sbjct: 179 CTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVC-LNDGRMTLVGIISWG 237 Query: 239 SRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 GC + P VYT+V+ Y+DWI + M+ Sbjct: 238 --LGCGQKDVPGVYTKVTNYLDWIRDNMR 264 >2OCV-B nrPDB Length = 259 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 87/260 (33%), Positives = 113/260 (43%), Gaps = 29/260 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHCI Sbjct: 1 IVEGWDAEKGIAPWQVML--FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + ++ I+VH R+N L DIAL+KL + V SD I Sbjct: 59 LLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPV 118 Query: 141 CLPEKD---SLLPKDYPCYVTGWGRLWT------NGPIADKLQQGLQPVVDHATCSRIDW 191 CLP+K SLL Y VTGWG L N LQ P+V+ C Sbjct: 119 CLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKAST- 177 Query: 192 WGFRVKKTMVCAG----GDGVISACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRGCNTR 246 R+ M CAG AC GDSGGP + N W GIVS+G GC+ + Sbjct: 178 -RIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG--EGCDRK 234 Query: 247 KKPVVYTRVSAYIDWINEKM 266 K YT V WI + + Sbjct: 235 GKYGFYTHVFRLKAWIQKVI 254 >1VR1-H nrPDB Length = 261 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 85/262 (32%), Positives = 118/262 (45%), Gaps = 29/262 (11%) Query: 30 VVGGEDARPHSWPWQISL--QYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNT 79 +V G DA PWQ+ L ++ ++ R CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 80 RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQ 138 V +GK++ + ++ I++H R+N L DIAL+KL + V SD I Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 139 VACLPEKD---SLLPKDYPCYVTGWGRLWTNGP------IADKLQQGLQPVVDHATCSRI 189 CLP+++ SLL Y VTGWG L LQ P+V+ C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK-- 178 Query: 190 DWWGFRVKKTMVCA---GGDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRGCN 244 D R+ M CA +G AC GDSGGP + N W GIVS+G GC+ Sbjct: 179 DSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG--EGCD 236 Query: 245 TRKKPVVYTRVSAYIDWINEKM 266 K YT V WI + + Sbjct: 237 RDGKYGFYTHVFRLKKWIQKVI 258 >1SGF-G nrPDB Length = 237 Score = 266 bits (681), Expect = 7e-72, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 119/250 (47%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +S PW +++ ++ CGG L+ N+VLTAAHC + Y+V +GKN Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYT----QYLCGGVLLDPNWVLTAAHCYDD--NYKVWLGKN 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALL-----------LRNDIALIKLAEHVELSDTIQ 138 NL +DE + V H +N L ND+ L++L++ +++DT++ Sbjct: 55 NL-FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVK 197 LP ++ L C +GWG + T D L ++ + C++ +V Sbjct: 114 PITLPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHI--EKVT 169 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 M+CAG DG C GDSGGPL C + GI S+G C P VYT+++ Sbjct: 170 DAMLCAGEMDGGKDTCKGDSGGPLICD-----GVLQGITSWG-HTPCGEPDMPGVYTKLN 223 Query: 257 AYIDWINEKM 266 + WI + M Sbjct: 224 KFTSWIKDTM 233 >4J1Y-A nrPDB Length = 397 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 84/276 (30%), Positives = 123/276 (44%), Gaps = 31/276 (11%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C CGVP P AR +GG DA ++PWQ+ ++ W GG LI +V Sbjct: 127 LPKCVPVCGVPREPFEEKARAIGGSDADIKNFPWQV----FFDNPWA---GGALINEYWV 179 Query: 70 LTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-------ALLLRNDI 122 LTAAH + R + VG +++ S + + + +H W NDI Sbjct: 180 LTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDI 239 Query: 123 ALIKLAEHVELSDTIQVACLP--EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV 180 AL++L + V++ T+ CLP D L ++GWGR A +L+ PV Sbjct: 240 ALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPV 298 Query: 181 VDHATCSRIDWWG-------FRVKKTMVCAGGDGVISACNGDSGGPLNCQLENG--SWEV 231 C + + M+CAGG+ + +C GDSGG Q N + Sbjct: 299 APLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYA 358 Query: 232 FGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 G+VS+G + C T +YTRV Y+DWI + MQ Sbjct: 359 AGLVSWGPQ--CGT---YGLYTRVKNYVDWIMKTMQ 389 >1ETT-H nrPDB Length = 259 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 85/260 (32%), Positives = 116/260 (44%), Gaps = 29/260 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G+DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + + +D I++H R+N L DIAL+KL +ELSD I Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 141 CLPEKDS---LLPKDYPCYVTGWGR------LWTNGPIADKLQQGLQPVVDHATCSRIDW 191 CLP+K + LL + VTGWG LQ P+V+ C Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST- 177 Query: 192 WGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRGCNTR 246 R+ M CAG G+G AC GDSGGP + N W GIVS+G GC+ Sbjct: 178 -RIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG--EGCDRD 234 Query: 247 KKPVVYTRVSAYIDWINEKM 266 K YT V WI + + Sbjct: 235 GKYGFYTHVFRLKKWIQKVI 254 >3G01-A nrPDB Length = 227 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 114/239 (47%), Gaps = 14/239 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + PHS P+ ++LK + CGG L+ FVLTAAHC R+ V +G + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC--KGRSMTVTLGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ ++E + V H +N NDI L+KL + + + ++ LP +++ + Sbjct: 59 NIKAKEE-TQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHV 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 CYV GWG++ +G L + V C + + +C G + Sbjct: 118 KPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCES-QFQSSYNRANEICVGDSKIK 176 Query: 210 SA-CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 A GDSGGPL C+ GIVS+G G P V+TRV +++ WI + M+ Sbjct: 177 GASFRGDSGGPLVCKRA-----AAGIVSYGQTDGSA----PQVFTRVLSFVSWIKKTMK 226 >1YC0-A nrPDB Length = 283 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 87/277 (31%), Positives = 140/277 (50%), Gaps = 24/277 (8%) Query: 6 VLAALLACA----SSCGVPSFPPN-LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60 +LA L A +CG L R++GG + P S PW ++ + C Sbjct: 7 LLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS-----FCA 61 Query: 61 GTLIASNFVLTAAHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL 117 G+L+ + +V++AAHC S++ + V +G++ + F G++ + ++ Sbjct: 62 GSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTF-GIEKYIPYTLYSVFN 120 Query: 118 -LRNDIALIKLAEH----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTN-GPIAD 171 +D+ LI+L + S +Q CLPE S P + C + GWG L N + Sbjct: 121 PSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSS 180 Query: 172 KLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWE 230 L++ L P+V CS + +G + M+CAG D AC GDSGGPL C+ +NG Sbjct: 181 SLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACE-KNGVAY 239 Query: 231 VFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 ++GI+S+G GC KP VYTRV+ Y+DWIN++++ Sbjct: 240 LYGIISWGD--GCGRLHKPGVYTRVANYVDWINDRIR 274 >1A5I-A nrPDB Length = 265 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 87/271 (32%), Positives = 136/271 (50%), Gaps = 24/271 (8%) Query: 16 SCGVPSFP-PNLSARVVGGEDARPHSWPWQISL--QYLKNDTWRHTCGGTLIASNFVLTA 72 +CG+ + P L + GG S PWQ ++ Q ++ R CGG LI+S +VLTA Sbjct: 1 TCGLRKYKEPQLHST--GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTA 58 Query: 73 AHCISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAE 129 AHC + +V +G+ V+ E V VHK ++ NDIAL++L Sbjct: 59 AHCFQESYLPDQLKVVLGRT-YRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKS 117 Query: 130 H----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHA 184 + SD+++ CLPE + LP C ++G+G+ ++ P +++L++G + + Sbjct: 118 DSPQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSS 177 Query: 185 TCSRIDWWGFRVKKTMVCAGG-------DGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237 C+ + V M+CAG V AC GDSGGPL C +N + GI+S+ Sbjct: 178 RCAPKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDN-HMTLLGIISW 236 Query: 238 GSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 G GC + P VYT+V+ Y+ WI + M L Sbjct: 237 GV--GCGEKDVPGVYTKVTNYLGWIRDNMHL 265 >3E0N-B nrPDB Length = 271 Score = 262 bits (671), Expect = 9e-71, Method: Composition-based stats. Identities = 85/248 (34%), Positives = 124/248 (50%), Gaps = 20/248 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR---TYRVAV 86 + GG A WPWQ+S+ Y H CGG+L++ +VL+AAHC + Y V + Sbjct: 1 ITGGSSAVAGQWPWQVSITY----EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G + L+ E+ + + I H + + DIAL++L+ + S I+ LP Sbjct: 57 GAHQLDSYSEDAKV-STLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQ 115 Query: 147 SLLPKDYPCYVTGWGRLWTNGPI--ADKLQQGLQPVVDHATCSRID------WWGFRVKK 198 + P C VTGWG + + + LQQ P++ TC+ + V++ Sbjct: 116 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQE 175 Query: 199 TMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSA 257 MVCAG +G AC GDSGGPL+C +E G W + GIVS+G C R +P VYT S+ Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVE-GLWYLTGIVSWGDA--CGARNRPGVYTLASS 232 Query: 258 YIDWINEK 265 Y WI K Sbjct: 233 YASWIQSK 240 >3DFJ-A nrPDB Length = 263 Score = 262 bits (671), Expect = 9e-71, Method: Composition-based stats. Identities = 85/248 (34%), Positives = 125/248 (50%), Gaps = 20/248 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR---TYRVAV 86 + GG A WPWQ+S+ Y H CGG+L++ +VL+AAHC + Y V + Sbjct: 1 ITGGSSAVAGQWPWQVSITY----EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G + L+ E+ + + I H + + DIAL++L+ + S I+ LP + Sbjct: 57 GAHQLDSYSEDAKV-STLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAN 115 Query: 147 SLLPKDYPCYVTGWGRLWTNGPI--ADKLQQGLQPVVDHATCSRID------WWGFRVKK 198 + P C VTGWG + + + LQQ P++ TC+ + V++ Sbjct: 116 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQE 175 Query: 199 TMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSA 257 MVCAG +G AC GDSGGPL+C +E G W + GIVS+G C R +P VYT S+ Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCPVE-GLWYLTGIVSWGDA--CGARNRPGVYTLASS 232 Query: 258 YIDWINEK 265 Y WI K Sbjct: 233 YASWIQSK 240 >2F91-A nrPDB Length = 237 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 120/242 (49%), Gaps = 13/242 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI-----SNTRTYRV 84 +VGG DA +P+Q+S Q H CG ++ N+ +TA HC+ N ++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 85 AVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE 144 G+ ++ V +E + V I +H+ ++ LL NDI+L+KL+ + +D + LPE Sbjct: 61 VAGELDMSV-NEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPE 119 Query: 145 KDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG 204 + VTGWG G D LQ+ P+V C R D+ + +M+CAG Sbjct: 120 QGHT--ATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDC-RADYGADEILDSMICAG 176 Query: 205 -GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 +G +C GDSGGPL GS + GIVS+G GC P VYT VS ++DWI Sbjct: 177 VPEGGKDSCQGDSGGPLAASD-TGSTYLAGIVSWG--YGCARPGYPGVYTEVSYHVDWIK 233 Query: 264 EK 265 Sbjct: 234 AN 235 >2EEK-A nrPDB Length = 220 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 122/238 (51%), Gaps = 20/238 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS Q+SL ++ H CGG+L++ ++V++AAHC + RV +G++ Sbjct: 1 IVGGYECTKHSQAHQVSL-----NSGYHFCGGSLVSKDWVVSAAHCYKS--VLRVRLGEH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 ++ V +E ++ ++ H +++ + NDI LIKL + L+ + LP Sbjct: 54 HIRV-NEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPT--ECA 110 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGV 208 C V+GWG ++ DKLQ P++ HA C + + + ++M CAG +G Sbjct: 111 ADATMCTVSGWGNTMSSVADGDKLQCLSLPILSHADC--ANSYPGMITQSMFCAGYLEGG 168 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +C GDSGGP+ C + G+VS+G GC R P VY +V W+ + M Sbjct: 169 KDSCQGDSGGPVVCN-----GVLQGVVSWG--YGCAERDHPGVYAKVCVLSGWVRDTM 219 >1NPM-A nrPDB Length = 225 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 72/241 (29%), Positives = 105/241 (43%), Gaps = 21/241 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G + PHS PWQ +L R CGG L+ +VLTAAHC + Y V +G + Sbjct: 1 ILEGRECIPHSQPWQAALF----QGERLICGGVLVGDRWVLTAAHC--KKQKYSVRLGDH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRW---NALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 +L+ D+ + V H + N +DI LI+L L D ++ L + Sbjct: 55 SLQSRDQP-EQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--AN 111 Query: 147 SLLPKDYPCYVTGWGR-LWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 C ++GWG + L + C R + ++ + MVCAG Sbjct: 112 LCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERA--YPGKITEGMVCAGS 169 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 C GDSGGPL C + GI S+GS C +KP VYT++ Y WI + Sbjct: 170 SNGADTCQGDSGGPLVCD-----GMLQGITSWGS-DPCGKPEKPGVYTKICRYTTWIKKT 223 Query: 266 M 266 M Sbjct: 224 M 224 >1NN6-A nrPDB Length = 228 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 81/241 (33%), Positives = 119/241 (49%), Gaps = 16/241 (6%) Query: 28 ARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVG 87 ++GG + +PHS P+ L+ + ++ CGG LI NFVLTAAHC R+ V +G Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--AGRSITVTLG 58 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +N+ E+E+ + V H ++N L +DI L+KL E L+ + P + + Sbjct: 59 AHNIT-EEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 117 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +P C V GWGR P +D LQ+ ++D CS + + +C G Sbjct: 118 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL---QLCVGNPR 174 Query: 208 V-ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 SA GDSGGPL C + GIVS+G K P V+TR+S Y WIN+ + Sbjct: 175 KTKSAFKGDSGGPLLC-----AGVAQGIVSYGRS----DAKPPAVFTRISHYRPWINQIL 225 Query: 267 Q 267 Q Sbjct: 226 Q 226 >4NFE-A nrPDB Length = 237 Score = 259 bits (663), Expect = 8e-70, Method: Composition-based stats. Identities = 80/250 (32%), Positives = 125/250 (50%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS PWQ+++ + W H CGG L+ +VLTAAHC+ + +V +G++ Sbjct: 1 IVGGWECEKHSQPWQVAVY---SHGWAH-CGGVLVHPQWVLTAAHCLK--KNSQVWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLL-----------RNDIALIKLAEHVELSDTIQ 138 NL E E+ V V H +N LL +D+ L++L+E +++D ++ Sbjct: 55 NL-FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCSRIDWWGFRVK 197 V LP ++ L CY +GWG + + LQ ++ + C+R + +V Sbjct: 114 VLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA--YSEKVT 169 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + M+CAG G C GDSGGPL C + GI S+G C +KP VYT+V Sbjct: 170 EFMLCAGLWTGGKDTCGGDSGGPLVCN-----GVLQGITSWGP-EPCALPEKPAVYTKVV 223 Query: 257 AYIDWINEKM 266 Y WI + + Sbjct: 224 HYRKWIKDTI 233 >5MS3-A nrPDB Length = 228 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 74/241 (30%), Positives = 107/241 (44%), Gaps = 21/241 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG + +PHS PWQ +L + CGG L+ N+VLTAAHC Y V +G + Sbjct: 1 VLGGHECQPHSQPWQAALF----QGQQLLCGGVLVGGNWVLTAAHC--KKPKYTVRLGDH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNA---LLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 +L+ +D + V H +N+ +D+ L++L + L ++ L D Sbjct: 55 SLQNKDGP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL--AD 111 Query: 147 SLLPKDYPCYVTGWGR-LWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 C V+GWG D L + C D + ++ MVCAG Sbjct: 112 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCE--DAYPGQITDGMVCAGS 169 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 C GDSGGPL C + GI S+GS C KP VYT + Y+DWI + Sbjct: 170 SKGADTCQGDSGGPLVCDGA-----LQGITSWGS-DPCGRSDKPGVYTNICRYLDWIKKI 223 Query: 266 M 266 + Sbjct: 224 I 224 >1IAU-A nrPDB Length = 227 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 71/241 (29%), Positives = 111/241 (46%), Gaps = 19/241 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ L + + CGG LI +FVLTAAHC ++ V +G + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLK-RCGGFLIRDDFVLTAAHCWGSS--INVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E E F+ V H +N NDI L++L + + +Q LP + + Sbjct: 58 NIK-EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR--IDWWGFRVKKTMVCAGGDG 207 C V GWG+ G + LQ+ V + C ++ + +C G Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---ELCVGDPE 173 Query: 208 -VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 ++ GDSGGPL C GIVS+G G P T+VS+++ WI + M Sbjct: 174 IKKTSFKGDSGGPLVCNK-----VAQGIVSYGRNNGM----PPRACTKVSSFVHWIKKTM 224 Query: 267 Q 267 + Sbjct: 225 K 225 >1FIZ-A nrPDB Length = 263 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 93/250 (37%), Positives = 130/250 (52%), Gaps = 15/250 (6%) Query: 30 VVGGEDARPHSWPWQISLQYL--KNDTWRHTCGGTLIASNFVLTAAHCISNTR---TYRV 84 VVGG A P +WPW +SLQ N+ HTCGG L+ S++VLTAAHC N + +R+ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 85 AVGKNNL----EVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140 G N + + V+ I +H+++ + L NDIALIK+ V I Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 141 CLPEKDSLLP-KDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKK 198 CLP+ + P C+VTGWG L GP + LQ+ ++D C+ W+ R++ Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 199 TMVCAGGDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 T VCAG C GDSGGPL C+ ++ V GI S+G GC K+P VYT Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV--GCARAKRPGVYTSTW 238 Query: 257 AYIDWINEKM 266 Y++WI K+ Sbjct: 239 PYLNWIASKI 248 >1SC8-U nrPDB Length = 262 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 79/263 (30%), Positives = 131/263 (49%), Gaps = 18/263 (6%) Query: 17 CGVPSFPPNLSARVVGGEDARPHSWPWQISLQY-LKNDTWRHTCGGTLIASNFVLTAAHC 75 CG + P +++GGE + PW ++ + + + CGG+LI+ +V++A HC Sbjct: 5 CGQKTLRPRF--KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHC 62 Query: 76 I---SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL--LRNDIALIKLAEH 130 Y V +G++ L + +G + V+ + +HK ++A NDIAL+K+ Sbjct: 63 FIDYPKKEDYIVYLGRSRLN-SNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSK 121 Query: 131 ----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHAT 185 + S TIQ LP + C +TG+G+ + ++L+ + ++ H Sbjct: 122 EGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRE 181 Query: 186 CSRIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCN 244 C + ++G V M+CA +C GDSGGPL C L+ G + GIVS+G RGC Sbjct: 182 CQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQ-GRMTLTGIVSWG--RGCA 238 Query: 245 TRKKPVVYTRVSAYIDWINEKMQ 267 + KP VYTRVS ++ WI + Sbjct: 239 LKDKPGVYTRVSHFLPWIRSHTK 261 >1FIW-A nrPDB Length = 290 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 88/250 (35%), Positives = 131/250 (52%), Gaps = 15/250 (6%) Query: 30 VVGGEDARPHSWPWQISLQYL--KNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRV 84 ++GG+DA +WPW +SLQ N+ H CGG+L+ S ++LTAAHC +R+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 85 AVGKNNLE----VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140 G +E + V+ I +H++++A NDIAL+K+ V I Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 141 CLPEKDSLLPK-DYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKK 198 CLP+ + P+ C+V GWG L N + LQ+ ++D C+ W+ R++ Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 199 TMVCAGG-DGVISACNGDSGGPLNCQL-ENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 T VCAG +G I C GDSGGPL C+ S+ V GI S+G GC K+P VYT Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV--GCARAKRPGVYTSTW 238 Query: 257 AYIDWINEKM 266 +Y++WI K+ Sbjct: 239 SYLNWIASKI 248 >2PSX-A nrPDB Length = 227 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 69/239 (28%), Positives = 104/239 (43%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G D H+ PWQ +L N + CG L+ ++LTAAHC + +RV +G Sbjct: 1 IINGSDCDMHTQPWQAALLLRPN---QLYCGAVLVHPQWLLTAAHC--RKKVFRVRLGHY 55 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 +L E G H ++ ND+ LIKL + + ++ + Sbjct: 56 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSS--HCP 113 Query: 150 PKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 C V+GWG + LQ V+ C D + ++ TM CAG Sbjct: 114 SAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCE--DAYPRQIDDTMFCAGDKAG 171 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +C GDSGGP+ C NGS + G+VS+G C +P VYT + + WI E +Q Sbjct: 172 RDSCQGDSGGPVVC---NGS--LQGLVSWGD-YPCARPNRPGVYTNLCKFTKWIQETIQ 224 >1FDP-A nrPDB Length = 235 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 77/243 (31%), Positives = 117/243 (48%), Gaps = 14/243 (5%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT--YR 83 R++GG +A H+ P+ S+Q H CGG L+A +VL+AAHC+ + + Sbjct: 4 PRGRILGGREAEAHARPYMASVQL----NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQ 59 Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP 143 V +G ++L E V H + +D+ L++L+E L ++ Sbjct: 60 VLLGAHSLSQP-EPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQ 118 Query: 144 EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 203 D + C V GWG + G D LQ L PV+D ATC+R + + ++CA Sbjct: 119 RVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA 178 Query: 204 GGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 +C GDSGGPL C + G+V+ GSR C RKKP +YTRV++Y WI+ Sbjct: 179 -ESNRRDSCKGDSGGPLVC-----GGVLEGVVTSGSRV-CGNRKKPGIYTRVASYAAWID 231 Query: 264 EKM 266 + Sbjct: 232 SVL 234 >3F6U-H nrPDB Length = 240 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 83/247 (33%), Positives = 120/247 (48%), Gaps = 19/247 (7%) Query: 31 VGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNN 90 + G+ R PWQ+ L + + CG LI ++VLTAAHC+ ++ V +G+ + Sbjct: 2 IDGKMTRRGDSPWQVVLL---DSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYD 58 Query: 91 LEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE----KD 146 L E+ L + + + VH ++ NDIAL+ LA+ LS TI CLP+ + Sbjct: 59 LRRW-EKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAER 117 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIAD-----KLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201 L VTGWG + A L PVV H CS + V + M+ Sbjct: 118 ELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMS--NMVSENML 175 Query: 202 CAGGDGVI-SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 260 CAG G AC GDSGGP+ G+W + G+VS+G GC VYT+VS Y+D Sbjct: 176 CAGILGDRQDACEGDSGGPMVASFH-GTWFLVGLVSWG--EGCGLLHNYGVYTKVSRYLD 232 Query: 261 WINEKMQ 267 WI+ ++ Sbjct: 233 WIHGHIR 239 >1SPJ-A nrPDB Length = 238 Score = 254 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 121/251 (48%), Gaps = 31/251 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS PWQ +L + CGG L+ +VLTAAHCIS+ Y++ +G++ Sbjct: 1 IVGGWECEQHSQPWQAALYHFS----TFQCGGILVHRQWVLTAAHCISD--NYQLWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-----------DIALIKLAEHV-ELSDTI 137 NL +DE + FV V H +N LL N D+ L++L E ++D + Sbjct: 55 NL-FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAV 113 Query: 138 QVACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 196 +V LP ++ + C +GWG + N D LQ ++ + C + +V Sbjct: 114 KVVELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHV--QKV 169 Query: 197 KKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 M+C G +G C GDSGGPL C + G+ S+G C T KP V RV Sbjct: 170 TDFMLCVGHLEGGKDTCVGDSGGPLMCD-----GVLQGVTSWG-YVPCGTPNKPSVAVRV 223 Query: 256 SAYIDWINEKM 266 +Y+ WI + + Sbjct: 224 LSYVKWIEDTI 234 >1Q3X-A nrPDB Length = 328 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 82/271 (30%), Positives = 119/271 (43%), Gaps = 26/271 (9%) Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 +L C CG+ + R+ GG+ A+P +PWQ+ + T G L+ N+ Sbjct: 68 SLPVCEPVCGLSA--RTTGGRIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNW 119 Query: 69 VLTAAHCI----SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL-LRNDIA 123 VLTAAH + + + +G + + + +H+ + NDIA Sbjct: 120 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQA---WSEAVFIHEGYTHDAGFDNDIA 176 Query: 124 LIKLAEHVELSDTIQVACLP--EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVV 181 LIKL V ++ I CLP E +S + D +GWG G +A L P+V Sbjct: 177 LIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIV 235 Query: 182 DHATC----SRIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPLN-CQLENGSWEVFGIV 235 DH C + + V M+CAG + G +C GDSGG L E W V GIV Sbjct: 236 DHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIV 295 Query: 236 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S+GS C + VYT+V YI WI + Sbjct: 296 SWGSMN-CGEAGQYGVYTKVINYIPWIENII 325 >3TK9-A nrPDB Length = 226 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 119/239 (49%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG +A+PHS P+ +Q+L+ + R CGG L+ +FVLTAAHC + V +G + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQ-EKSRKRCGGILVRKDFVLTAAHC--QGSSINVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E E F+ V H +N N+I L++L + + ++ LP + + Sbjct: 58 NIK-EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 C V GWG + + +A LQ+ L V C R+ + G + T +C G Sbjct: 117 KPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERL-FHGNYSRATEICVGDPKKT 174 Query: 210 SA-CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 GDSGGPL C+ GI+S+G+++G P VY +VS ++ WI M+ Sbjct: 175 QTGFKGDSGGPLVCKD-----VAQGILSYGNKKG----TPPGVYIKVSHFLPWIKRTMK 224 >6QHB-A nrPDB Length = 223 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 114/238 (47%), Gaps = 19/238 (7%) Query: 31 VGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNN 90 V G S P+Q +L + CGG LI +VLTAAHC +V +GK+N Sbjct: 2 VHGGPCDKTSHPYQAALYT----SGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHN 55 Query: 91 LEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLP 150 L ++ V + H ++A DI L++LA +LS+ IQ LP + Sbjct: 56 LGQQESSQEQSSVVRAVI-HPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSA 112 Query: 151 KDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG-VI 209 + C++ GWG+ +G D +Q +V C + ++ + M+CAG + Sbjct: 113 QTTSCHILGWGKT-ADGDFPDTIQCAYIHLVSREECE--HAYPGQITQNMLCAGDEKYGK 169 Query: 210 SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +C GDSGGPL C + G+VS+G C +++KP VYT V Y +WI + +Q Sbjct: 170 DSCQGDSGGPLVCGDH-----LRGLVSWG-NIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >4Z6A-H nrPDB Length = 249 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 79/245 (32%), Positives = 121/245 (49%), Gaps = 17/245 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR---VAV 86 +VGG+ PWQ+ L CGGTLI + +V++AAHC + +R + Sbjct: 1 IVGGKVCPKGECPWQVLLLV----NGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK- 145 G+++L E + V + + + +DIAL++L + V L+D + CLPE+ Sbjct: 57 GEHDLS-EHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERT 115 Query: 146 --DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 203 + L V+GWG+L G A +L P + C + ++ + M CA Sbjct: 116 FSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEAS--YPGKITEYMFCA 173 Query: 204 GG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 G DG +C GDSGGP G+W + GIVS+G +GC T VYTRVS YI+W+ Sbjct: 174 GYSDGSKDSCKGDSGGPHATH-YRGTWYLTGIVSWG--QGCATVGHFGVYTRVSQYIEWL 230 Query: 263 NEKMQ 267 + M+ Sbjct: 231 QKLMR 235 >1GPZ-A nrPDB Length = 399 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 77/273 (28%), Positives = 119/273 (43%), Gaps = 29/273 (10%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 + C CG P P +++GG+ A+ ++PWQ+ GG L+ ++ Sbjct: 138 IPRCLPVCGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWI 191 Query: 70 LTAAHCI-------SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-- 120 LTAAH + + + V +G N+E + G+ + + VH + N Sbjct: 192 LTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGN--HPIRRVSVHPDYRQDESYNFE 249 Query: 121 -DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQP 179 DIAL++L V L + CLP+ D+ YV+G+G + IA L+ P Sbjct: 250 GDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLP 307 Query: 180 VVDHATCSRIDWWGFR---VKKTMVCAGGDGVI-SACNGDSGGPLNCQLEN-GSWEVFGI 234 V + C R + M CAG + AC GDSGG + N W GI Sbjct: 308 VANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGI 367 Query: 235 VSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 VS+G GC+ YT+V Y+DWI ++M+ Sbjct: 368 VSWGI--GCSRG--YGFYTKVLNYVDWIKKEME 396 >2R0L-A nrPDB Length = 248 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 79/248 (31%), Positives = 130/248 (52%), Gaps = 19/248 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT---RTYRVAV 86 ++GG + P S PW ++ + C G+L+ + +V++AAHC S++ + V + Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 55 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALL-LRNDIALIKLAEH----VELSDTIQVAC 141 G++ + F G++ + ++ +D+ LI+L + S +Q C Sbjct: 56 GQHFFNRTTDVTQTF-GIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 114 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTM 200 LPE S P + C + GWG L N + L++ L P+V CS + +G + M Sbjct: 115 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 174 Query: 201 VCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYI 259 +CAG D AC GDSGGPL C+ +NG ++GI+S+G GC KP VYTRV+ Y+ Sbjct: 175 LCAGYFDCKSDACQGDSGGPLACE-KNGVAYLYGIISWGD--GCGRLHKPGVYTRVANYV 231 Query: 260 DWINEKMQ 267 DWIN++++ Sbjct: 232 DWINDRIR 239 >1MD7-A nrPDB Length = 328 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 77/273 (28%), Positives = 119/273 (43%), Gaps = 29/273 (10%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 + C CG P P R++GG+ A+ ++PWQ+ GG L+ ++ Sbjct: 70 IPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWI 123 Query: 70 LTAAHCI-------SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-- 120 LTAAH + + + V +G N+E + G+ + + VH + N Sbjct: 124 LTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGN--HPIRRVSVHPDYRQDESYNFE 181 Query: 121 -DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQP 179 DIAL++L V L + CLP+ D+ YV+G+G + IA L+ P Sbjct: 182 GDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLP 239 Query: 180 VVDHATCSRIDWWGFR---VKKTMVCAGGDGVI-SACNGDSGGPLNCQLEN-GSWEVFGI 234 V + C R + M CAG + AC GD+GG + N W GI Sbjct: 240 VANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGI 299 Query: 235 VSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 VS+G GC+ YT+V Y+DWI ++M+ Sbjct: 300 VSWGI--GCSRG--YGFYTKVLNYVDWIKKEME 328 >5TO3-B nrPDB Length = 409 Score = 250 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 85/260 (32%), Positives = 115/260 (44%), Gaps = 29/260 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + ++ I++H R+N L DIAL+KL + V SD I Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 141 CLPEKD---SLLPKDYPCYVTGWGRLWTNGP------IADKLQQGLQPVVDHATCSRIDW 191 CLP+++ SLL Y VTGWG L LQ P+V+ C D Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK--DS 176 Query: 192 WGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQLE-NGSWEVFGIVSFGSRRGCNTR 246 R+ M CAG +G AC GDSGGP + N W GIVS G+ GC+ Sbjct: 177 TRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA--GCDRD 234 Query: 247 KKPVVYTRVSAYIDWINEKM 266 K YT V WI + + Sbjct: 235 GKYGFYTHVFRLKKWIQKVI 254 >4IW4-E nrPDB Length = 279 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 81/272 (29%), Positives = 127/272 (46%), Gaps = 37/272 (13%) Query: 30 VVGGEDARPHSWPWQISL-----QYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT--- 81 ++GG +A P +PWQ + + ND W + G L++++++LTAAH + + R Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGS--GALLSASWILTAAHVLRSQRRDTT 58 Query: 82 --------YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVEL 133 V +G ++ V D+ G++ + +H +N +DIAL++L E V L Sbjct: 59 VIPVSKEHVTVYLGLHD--VRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPL 116 Query: 134 SDTIQVACLPEKDSLLPKDYP-CYVTGWGRLWTN-----------GPIADKLQQGLQPVV 181 + CLP + P + V GWG N ++D LQ PVV Sbjct: 117 GPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVV 176 Query: 182 DHATCS---RIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLE-NGSWEVFGIVS 236 HA C + V + M CAG +G C GDSGG + + W V G+VS Sbjct: 177 PHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVS 236 Query: 237 FGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 +G C +++ VYT+VS Y+DW+ E+M L Sbjct: 237 WGGPEECGSKQVYGVYTKVSNYVDWVWEQMGL 268 >3QUM-P nrPDB Length = 237 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 82/250 (32%), Positives = 127/250 (50%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG + HS PWQ+ + R CGG L+ +VLTAAHCI N + +G++ Sbjct: 1 IVGGWECEKHSQPWQVLV----ASRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-----------DIALIKLAEHVELSDTIQ 138 +L ++ G +F V H ++ LL+N D+ L++L+E EL+D ++ Sbjct: 55 SLFHPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCSRIDWWGFRVK 197 V LP ++ L CY +GWG + + KLQ V+ + C+++ +V Sbjct: 114 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVT 169 Query: 198 KTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 K M+CAG G S C+GDSGGPL C + GI S+GS C ++P +YT+V Sbjct: 170 KFMLCAGRWTGGKSTCSGDSGGPLVCN-----GVLQGITSWGS-EPCALPERPSLYTKVV 223 Query: 257 AYIDWINEKM 266 Y WI + + Sbjct: 224 HYRKWIKDTI 233 >5UBM-A nrPDB Length = 252 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 76/257 (29%), Positives = 116/257 (45%), Gaps = 31/257 (12%) Query: 29 RVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGK 88 R++GG DA ++PWQ+ ++ W GG LI +VLTAAH + R + VG Sbjct: 1 RIIGGSDADIKNFPWQV----FFDNPWA---GGALINEYWVLTAAHVVEGNREPTMYVGS 53 Query: 89 NNLEVEDEEGSLFVGVDTIHVHKRWN-------ALLLRNDIALIKLAEHVELSDTIQVAC 141 +++ S + + + +H W NDIAL++L + V++ T+ C Sbjct: 54 TSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 142 LP--EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWG------ 193 LP D L ++GWGR A +L+ PV C + Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAE 172 Query: 194 -FRVKKTMVCAGGDGVISACNGDSGGPLNCQLENG--SWEVFGIVSFGSRRGCNTRKKPV 250 + M+CAGG+ + +C GDSGG Q N + G+VS+G + C T Sbjct: 173 AYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ--CGT---YG 227 Query: 251 VYTRVSAYIDWINEKMQ 267 +YTRV Y+DWI + MQ Sbjct: 228 LYTRVKNYVDWIMKTMQ 244 >1ZJK-A nrPDB Length = 403 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 81/271 (29%), Positives = 119/271 (43%), Gaps = 26/271 (9%) Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68 +L C CG+ + ++ GG+ A+P +PWQ+ + T G L+ N+ Sbjct: 143 SLPVCEPVCGLSA--RTTGGQIYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNW 194 Query: 69 VLTAAHCI----SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL-LRNDIA 123 VLTAAH + + + +G + + + +H+ + NDIA Sbjct: 195 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQA---WSEAVFIHEGYTHDAGFDNDIA 251 Query: 124 LIKLAEHVELSDTIQVACLP--EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVV 181 LIKL V ++ I CLP E +S + D +GWG G +A L P+V Sbjct: 252 LIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIV 310 Query: 182 DHATC----SRIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPLN-CQLENGSWEVFGIV 235 DH C + + V M+CAG + G +C GDSGG L E W V GIV Sbjct: 311 DHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIV 370 Query: 236 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 S+GS C + VYT+V YI WI + Sbjct: 371 SWGSMN-CGEAGQYGVYTKVINYIPWIENII 400 >5LHN-A nrPDB Length = 247 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 78/250 (31%), Positives = 124/250 (49%), Gaps = 17/250 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLK--NDTWRHTCGGTLIASNFVLTAAHCI---SNTRTYRV 84 +VGGE + PW ++ CGG+LI+ +V +AAHC Y V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 85 AVGKNNLEVEDEEGSLFVGVDTIHVHKRW--NALLLRNDIALIKLAEH----VELSDTIQ 138 +G+ + E G + V+ + +H+ + ++L NDIAL+K+ + S +IQ Sbjct: 61 YLGQ-SKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQ 119 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVK 197 LP + + P C +TG+G+ + L+ + +V H C + ++G + Sbjct: 120 TIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEIN 179 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 M+CA + +C GDSGGPL C +E G + GIVS+G RGC + KP VYTRVS Sbjct: 180 YKMLCAADPEWKTDSCKGDSGGPLICNIE-GRPTLSGIVSWG--RGCAEKNKPGVYTRVS 236 Query: 257 AYIDWINEKM 266 ++DWI + Sbjct: 237 HFLDWIQSHI 246 >5FCR-A nrPDB Length = 234 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 75/239 (31%), Positives = 116/239 (48%), Gaps = 15/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTYRVAV 86 ++GG++A H+ P+ S+Q H CGGTL+ +VL+AAHC +++ + +V + Sbjct: 1 ILGGQEAAAHARPYMASVQV----NGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G ++L E + V ++ H L +D+ L KL+++ L ++ L +D Sbjct: 57 GAHSLSAP-EPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYED 115 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 + C V GWG + G D L Q +++ TC+ + V M+CA Sbjct: 116 KEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA-ES 174 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 C GDSG PL C V G+V++GSR C KKP VYTRVS+Y WI Sbjct: 175 NRRDTCRGDSGSPLVCGDA-----VEGVVTWGSRV-CGNGKKPGVYTRVSSYRMWIENI 227 >1AO5-A nrPDB Length = 237 Score = 247 bits (631), Expect = 3e-66, Method: Composition-based stats. Identities = 74/250 (29%), Positives = 116/250 (46%), Gaps = 30/250 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG + +S PWQ+++ Y K H CGG L+ N+VLTAAHC + Y V +GKN Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKN 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALL-----------LRNDIALIKLAEHVELSDTIQ 138 L ++E + V H +N L +D+ L++L++ +++D ++ Sbjct: 55 KL-FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVK 197 LP K+ C +GWG + T D LQ ++ + C+++ + +V Sbjct: 114 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV--YLQKVT 169 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 M+CAG G C DSGGPL C + G S+G C P +YT + Sbjct: 170 DVMLCAGEMGGGKDTCRDDSGGPLICD-----GILQGTTSYGPV-PCGKPGVPAIYTNLI 223 Query: 257 AYIDWINEKM 266 + WI + M Sbjct: 224 KFNSWIKDTM 233 >2XRC-A nrPDB Length = 565 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 92/255 (36%), Positives = 134/255 (52%), Gaps = 19/255 (7%) Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75 SCGV + R+VGG+ A+ PWQ++++ D TCGG I ++LTAAHC Sbjct: 308 SCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHC 363 Query: 76 ISNTRTYRVAVGKNNLE--VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH--- 130 + ++T+R + ++ D + + VD I H+ +NA +NDIALI++ + Sbjct: 364 LRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNK 423 Query: 131 --VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR 188 EL +I AC+P L + C V+GWGR N + LQ G ++ + CS+ Sbjct: 424 KDCELPRSI-PACVPWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISN--CSK 479 Query: 189 IDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRK 247 + +K M CAG DG I AC GDSGGPL C N V+G+VS+G C + Sbjct: 480 F-YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN--CGKPE 536 Query: 248 KPVVYTRVSAYIDWI 262 P VYT+V+ Y DWI Sbjct: 537 FPGVYTKVANYFDWI 551 >1ORF-A nrPDB Length = 234 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 69/242 (28%), Positives = 119/242 (49%), Gaps = 15/242 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + PHS P+ + L + + C G LIA ++VLTAAHC N R+ +V +G + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKRS-QVILGAH 55 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 ++ +E + V + ++ D+ L++L E +++ + + LP+K + Sbjct: 56 SIT-REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDV 114 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFR--VKKTMVCAGG-D 206 C V GWGR + +D L++ ++D C+ + + F + MVCAG Sbjct: 115 KPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 174 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS-AYIDWINEK 265 G +CNGDSG PL C+ G+ SFG C + P VY +S +++WI Sbjct: 175 GGRDSCNGDSGSPLLCE-----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 229 Query: 266 MQ 267 ++ Sbjct: 230 IK 231 >1TON-A nrPDB Length = 235 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 74/251 (29%), Positives = 116/251 (46%), Gaps = 32/251 (12%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +S PWQ+++ + CGG LI ++V+TAAHC SN Y+V +G+N Sbjct: 1 IVGGYKCEKNSQPWQVAVIN------EYLCGGVLIDPSWVITAAHCYSN--NYQVLLGRN 52 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNAL-----------LLRNDIALIKLAEHVELSDTIQ 138 NL +DE + V H + L ND+ L+ L+E +++ ++ Sbjct: 53 NL-FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVK 111 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVK 197 V LP K+ C +GWG + ++ LQ ++ + C I+ + V Sbjct: 112 VIDLPTKE--PKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKC--IETYKDNVT 167 Query: 198 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 M+CAG +G C GDSGGPL C + GI S G C K P +Y ++ Sbjct: 168 DVMLCAGEMEGGKDTCAGDSGGPLICD-----GVLQGITS-GGATPCAKPKTPAIYAKLI 221 Query: 257 AYIDWINEKMQ 267 + WI + M+ Sbjct: 222 KFTSWIKKVMK 232 >3RP2-A nrPDB Length = 224 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 117/238 (49%), Gaps = 16/238 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG ++ PHS P+ L + R CGG LI+ FVLTAAHC R V +G + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC--KGREITVILGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 ++ + E + V+ +H+ +N++ +DI L+KL + VEL+ + V LP + Sbjct: 59 DV-RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFI 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 208 C+ GWG+ P + L++ ++D C ++ ++ VC G Sbjct: 118 HPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKF---QVCVGSPTTL 174 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +A GDSGGPL C + GIVS+G K P ++TRVS Y+ WIN + Sbjct: 175 RAAFMGDSGGPLLC-----AGVAHGIVSYGHP----DAKPPAIFTRVSTYVPWINAVI 223 >3BSQ-A nrPDB Length = 227 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 69/240 (28%), Positives = 109/240 (45%), Gaps = 21/240 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G S PWQ++L + CGG L+ +VLTAAHC Y V +G + Sbjct: 1 IIDGAPCARGSHPWQVALL----SGNQLHCGGVLVNERWVLTAAHC--KMNEYTVHLGSD 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 L + + + H ++ ND+ L+KL LS ++ LP + Sbjct: 55 TLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR--CE 109 Query: 150 PKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 P C V+GWG + + L ++ C+++ + ++ +M+CAG D Sbjct: 110 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLCAGIPDS 167 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +ACNGDSGGPL C + G+VS+G C P VYT+V + WIN+ M+ Sbjct: 168 KKNACNGDSGGPLVC-----RGTLQGLVSWG-TFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >4XDE-A nrPDB Length = 257 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 80/247 (32%), Positives = 119/247 (48%), Gaps = 20/247 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRTYRVAV 86 VVGG A + P+ +L + C G+LIA +VLTAAHC+ + V + Sbjct: 3 VVGGLVALRGAHPYIAALYW-----GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 57 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVE-----LSDTIQVAC 141 G+ E + V + +H+ ++ + ++D+AL++L E + LS +Q Sbjct: 58 GQERRNHSCEPC-QTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVS 116 Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTM 200 LP + + C V GWG + A LQ+ P + CS D G + M Sbjct: 117 LPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGM 176 Query: 201 VCAGG-DGVISACNGDSGGPLNCQLE--NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSA 257 +CAG +G AC GDSGGPL C+ + + GI+S+GS GC R KP VYT V+ Sbjct: 177 LCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS--GCGDRNKPGVYTDVAY 234 Query: 258 YIDWINE 264 Y+ WI E Sbjct: 235 YLAWIRE 241 >4E7N-A nrPDB Length = 238 Score = 242 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 110/240 (45%), Gaps = 15/240 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG++ + + ++L ++ T CGGTLI +VLTAAHC + + +R+ +G + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRT--LFCGGTLINQEWVLTAAHC--DRKNFRIKLGMH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + +V +E+ V + N L DI LI+L V+ S I S Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSPP 114 Query: 150 PKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDW-WGFRVKKTMVCAG-GD 206 C + GWGR+ T G D ++++ C + +CAG + Sbjct: 115 SVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILE 174 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 G C GDSGGPL C NG ++ GI S+G C KP YT+V ++DWI + Sbjct: 175 GGKDTCKGDSGGPLIC---NGQFQ--GIASWGD-DPCAQPHKPAAYTKVFDHLDWIENII 228 >4GSO-A nrPDB Length = 232 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 109/239 (45%), Gaps = 19/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG++ + P+ L + CG TLI +V+TAAHC ++ +++ +G + Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-----YFCGLTLINQEWVVTAAHC--DSTNFQMQLGVH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + +V +E+ + + + +L DI LIKL + + S I LP + Sbjct: 54 SKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV 113 Query: 150 PKDYPCYVTGWGR-LWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 C + GWG N D +VD+ C + KT +CAG +G Sbjct: 114 --GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQ--GAYNGLPAKTTLCAGVLEG 169 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C GDSGGPL C NG ++ GIVS+G+ C KP +YT V Y DWI + Sbjct: 170 GKDTCVGDSGGPLIC---NGQFQ--GIVSYGAHS-CGQGPKPGIYTNVFDYTDWIQRNI 222 >2OLG-A nrPDB Length = 278 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 78/278 (28%), Positives = 131/278 (47%), Gaps = 28/278 (10%) Query: 11 LACAS-SCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHT-CGGTLIASNF 68 CG + +++ G+D P +PW + Y + + CGG+LI + + Sbjct: 7 PELLPNDCGYQV----EADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRY 62 Query: 69 VLTAAHCISNT------RTYRVAVGKNNLEVEDE----------EGSLFVGVDTIHVHKR 112 ++TAAHC++ +V +G+ N + + + + +G++ H Sbjct: 63 IVTAAHCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPD 122 Query: 113 WNALLLR--NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIA 170 + +DIALI+L VE ++ I+ CLP+ + + V GWGR T G + Sbjct: 123 YVDGSKDRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTET-GQYS 181 Query: 171 DKLQQGLQPVVDHATCSR-IDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSW 229 Q+ PVV C++ G RV+ + +CAGG+ +C GDSGGPL + N + Sbjct: 182 TIKQKLAVPVVHAEQCAKTFGAAGVRVRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQF 241 Query: 230 EVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + G+VSFG+ C T P +YT+V Y DWI ++ Sbjct: 242 FLEGLVSFGAT--CGTEGWPGIYTKVGKYRDWIEGNIR 277 >3S9B-A nrPDB Length = 234 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 106/238 (44%), Gaps = 15/238 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG++ + P+ ++L + T C G LI +VLTAAHC + R R+ +G + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH--CAGALINREWVLTAAHC--DRRNIRIKLGMH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + + +E+ + V L DI LI+L V S I LP + + Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGV 208 C + GWG++ T D +V H C + W +T +CAG G Sbjct: 117 --GSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRT-LCAGILKGG 172 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C+GDSGGPL C E + GIV+ G C KP VYT+V Y +WI + Sbjct: 173 RDTCHGDSGGPLICNGE-----MHGIVA-GGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >4BXW-A nrPDB Length = 423 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 87/262 (33%), Positives = 124/262 (47%), Gaps = 23/262 (8%) Query: 19 VPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN 78 S P+ R+V G D + PWQ +L K CGGT+++ +VLTAAHCI+ Sbjct: 159 KKSDNPSPDIRIVNGMDCKLGECPWQAALVDEKEG---VFCGGTILSPIYVLTAAHCINE 215 Query: 79 TRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNAL---------LLRNDIALIKLAE 129 T T V VG+ ++ E + VD I+VHK++ DIA+I++ Sbjct: 216 TETISVVVGE--IDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKT 273 Query: 130 HVELSDTIQVACLPEKD---SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATC 186 ++ S+ + ACLP D +L K V+G+GR+ GP + L+ P VD TC Sbjct: 274 PIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTC 333 Query: 187 SRIDWWGFRVKKTMVCAGGDG-VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 245 + M CAG D AC GDSGGP + + + GIVS G GC Sbjct: 334 MVSSETP--ITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHF-ITGIVSSG--EGCAR 388 Query: 246 RKKPVVYTRVSAYIDWINEKMQ 267 K YT++S +I WI M+ Sbjct: 389 NGKYGNYTKLSKFIPWIKRIMR 410 >4DJZ-B nrPDB Length = 251 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 71/258 (27%), Positives = 121/258 (46%), Gaps = 28/258 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS------------ 77 + G A+ + PW L +L CGG+L+ S++++TAAHC+ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQP---FCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRD 57 Query: 78 ----NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVEL 133 + +++ +GK+ + +E +GV +H +++ ND+AL++L E L Sbjct: 58 SDLLSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVL 116 Query: 134 SDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWW- 192 + + CLPE + V+GWG+ + + L + P+VDH+TC + Sbjct: 117 NAFVMPICLPEGPQ--QEGAMVIVSGWGKQFLQ-RFPETLMEIEIPIVDHSTCQKAYAPL 173 Query: 193 GFRVKKTMVCAGG-DGVISACNGDSGGPLN-CQLENGSWEVFGIVSFGSRRGCNTRKKPV 250 +V + M+CAG +G AC GDSGGP+ E G W + G VS+G C + + Sbjct: 174 KKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD--CGKKDRYG 231 Query: 251 VYTRVSAYIDWINEKMQL 268 VY+ + DWI + Sbjct: 232 VYSYIHHNKDWIQRVTGV 249 >1SGF-A nrPDB Length = 240 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 72/245 (29%), Positives = 111/245 (45%), Gaps = 31/245 (12%) Query: 35 DARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVE 94 D +S PW +++ ++ CGG L+ N+VLTAAHC ++ Y+V +GKNN +E Sbjct: 10 DCE-NSQPWHVAVYRFN----KYQCGGVLLDRNWVLTAAHCYNDK--YQVWLGKNNF-LE 61 Query: 95 DEEGSLFVGVDTIHVHKRWNA-----------LLLRNDIALIKLAEHVELSDTIQVACLP 143 DE V H +N ND+ L++L++ +++D ++ LP Sbjct: 62 DEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLP 121 Query: 144 EKDSLLPKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 ++ L C +GWG D LQ ++ + C + +V M+C Sbjct: 122 TEEPKL--GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAH--EMKVTDAMLC 177 Query: 203 AGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG DG C DSGGPL C + GI S+G C +P VYT++ + W Sbjct: 178 AGEMDGGSYTCEHDSGGPLICD-----GILQGITSWGP-EPCGEPTEPSVYTKLIKFSSW 231 Query: 262 INEKM 266 I E M Sbjct: 232 IRETM 236 >5ZFH-A nrPDB Length = 224 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 112/240 (46%), Gaps = 21/240 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G + S PWQ++L + CGG L+ +VLTAAHC Y+V +G + Sbjct: 1 IIDGYKCKEGSHPWQVALL----KGNQLHCGGVLVDKYWVLTAAHCKMGQ--YQVQLGSD 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + ++ + + H ++ NDI L++L E V++S ++ LP + Sbjct: 55 KIG---DQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLP--EHCE 109 Query: 150 PKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 P C V+GWG + + L ++ C ++ + + KTM+CAG D Sbjct: 110 PPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKV--YKDLLGKTMLCAGIPDS 167 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + CNGDSGGPL C + G+VS+G C P VYT+V Y W+ E M+ Sbjct: 168 KTNTCNGDSGGPLVCND-----TLQGLVSWG-TYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >1MZD-A nrPDB Length = 240 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 74/245 (30%), Positives = 115/245 (46%), Gaps = 21/245 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTYRVAV 86 ++GG++ PHS P+ S+QY H CGG LI +VLTAAHC + ++ V + Sbjct: 3 IIGGKEVSPHSRPFMASIQY----GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 58 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G ++L ++E + + R + NDI L+KL +L+ +++ + K Sbjct: 59 GAHSLS-KNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT 117 Query: 147 SLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGF--RVKKTMVCA 203 S L C VTGWG + +D L++ V+ C+ ++ + K MVCA Sbjct: 118 S-LRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 204 GG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS-AYIDW 261 G G +C GD+GGPL C+ IVS G C KP +YT ++ Y W Sbjct: 177 GDAKGQKDSCKGDAGGPLICK-----GVFHAIVSGGHE--CGVATKPGIYTLLTKKYQTW 229 Query: 262 INEKM 266 I + Sbjct: 230 IKSNL 234 >1FUJ-A nrPDB Length = 221 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 85/240 (35%), Positives = 122/240 (50%), Gaps = 21/240 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN--TRTYRVAVG 87 +VGG +A+PHS P+ SLQ ++ + H CGGTLI +FVLTAAHC+ + R V +G Sbjct: 1 IVGGHEAQPHSRPYMASLQ-MRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLG 59 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +N+ + E V + + ++A NDI LI+L+ LS ++ LP++D Sbjct: 60 AHNVRTQ-EPTQQHFSVAQVFL-NNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQ 117 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 +P C GWGR+ + P A LQ+ VV C + F ++ AG Sbjct: 118 PVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHNICTFVPRRK---AG--- 170 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 C GDSGGPL C + GI SF GC TR P +TRV+ Y+DWI ++ Sbjct: 171 ---ICFGDSGGPLICD-----GIIQGIDSF-VIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >2XXL-A nrPDB Length = 408 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 82/262 (31%), Positives = 124/262 (47%), Gaps = 25/262 (9%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT--YR 83 LS RV G + + S PW L+Y + R CGG +I+ ++LTAAHC+ + Y Sbjct: 115 LSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYE 174 Query: 84 VAVGKNNLEVEDEEGSL-----------FVGVDTIHVHKRWNALLLRNDIALIKLAEHVE 132 + +G++ + E++ VG++ +H++++A + +DIAL+KL V Sbjct: 175 IRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVP 234 Query: 133 LSDTIQVACLPEKDSLLPKDYPC---YVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRI 189 I+ CLP D L K +VTGWG NG +D L Q P+ + CS+ Sbjct: 235 FQKHIKPICLPITDELKEKAEQISTYFVTGWG-TTENGSSSDVLLQANVPLQPRSACSQA 293 Query: 190 DWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLEN-----GSWEVFGIVSFGSRRGCN 244 + V + +C GG + +C GDSGGPL + FGIVS G C Sbjct: 294 --YRRAVPLSQLCVGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVT-CG 350 Query: 245 TRKKPVVYTRVSAYIDWINEKM 266 P +YT V Y+ WI + M Sbjct: 351 QISLPGLYTNVGEYVQWITDTM 372 >2AIQ-A nrPDB Length = 231 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 105/239 (43%), Gaps = 20/239 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG++ + + + + CGGTLI +VLTA HC + R+ +G + Sbjct: 1 VIGGDECNINEHRFLALVYANGS-----LCGGTLINQEWVLTARHC--DRGNMRIYLGMH 53 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 NL+V +++ + N + DI LI+L V S I LP + Sbjct: 54 NLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV 113 Query: 150 PKDYPCYVTGWGR-LWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 C + GWG N + D ++D+A C + T +CAG +G Sbjct: 114 --GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG---LAATTLCAGILEG 168 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C GDSGGPL C NG ++ GI+S G C +KP +YT+V Y DWI + Sbjct: 169 GKDTCKGDSGGPLIC---NGQFQ--GILSVG-GNPCAQPRKPGIYTKVFDYTDWIQSII 221 >2ZKS-A nrPDB Length = 240 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 77/239 (32%), Positives = 114/239 (47%), Gaps = 15/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI-SNTRTYRVAVGK 88 ++GG + PHS P+ SLQ H CGG L+ +VLTAAHC+ R+ +G Sbjct: 1 IIGGREVIPHSRPYMASLQR----NGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGL 56 Query: 89 NNLEVEDEEGSLFVGVDTIHVHKRWNA-LLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + L + L + H R+ L ND+AL++L V+ S TI+ LP K Sbjct: 57 HTL----DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQ 112 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC-AGGD 206 ++ C + GWG G ++ L++ V+D C+ +W + +MVC A Sbjct: 113 VVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADS 172 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 265 + C GDSGGPL C + G++SF S R C KP V T V+ Y+ WI + Sbjct: 173 KDQAPCKGDSGGPLVCGKGR---VLAGVLSF-SSRVCTDIFKPPVATAVAPYVSWIRKV 227 >5O32-I nrPDB Length = 244 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 87/241 (36%), Positives = 128/241 (53%), Gaps = 19/241 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG+ A+ PWQ++++ D TCGG I ++LTAAHC+ ++T+R + Sbjct: 1 IVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 56 Query: 90 NLE--VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH-----VELSDTIQVACL 142 ++ D + + VD I H+ +NA +NDIALI++ + EL +I AC+ Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI-PACV 115 Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202 P L + C V+GWGR N + LQ G ++ + CS+ + +K M C Sbjct: 116 PWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISN--CSKF-YGNRFYEKEMEC 171 Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261 AG DG I AC GDSGGPL C N V+G+VS+G C + P VYT+V+ Y DW Sbjct: 172 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN--CGKPEFPGVYTKVANYFDW 229 Query: 262 I 262 I Sbjct: 230 I 230 >2RDL-A nrPDB Length = 226 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 118/239 (49%), Gaps = 16/239 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + RPH+ P+ L+ + + C G LI NFV+TAAHC R+ V +G + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC--AGRSITVLLGAH 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N +V+ E+ + V+ H +++ L+ NDI L+KL E L+ + + K + + Sbjct: 59 NKKVK-EDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSI 117 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 208 P C GWGR N P +D LQ+ ++D C + + ++ +C G Sbjct: 118 PPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFH---QEPQLCVGNPKKI 174 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 + GDSGGPL C + GI S+ R K P V+TR+S Y WIN+ ++ Sbjct: 175 RNVYKGDSGGPLLC-----AGIAQGIASYVLRN----AKPPSVFTRISHYRPWINKILR 224 >2BDH-A nrPDB Length = 223 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 86/239 (35%), Positives = 116/239 (48%), Gaps = 18/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ GED PHS PWQ +L C G L+ +VL+AAHC N+ Y + +G + Sbjct: 1 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 +LE + E GS V H +N LL ND+ LIKL E V SDTI+ + Sbjct: 55 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCP 112 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA-GGDGV 208 C V+GWG L NG + LQ VV CS+ + +M CA GG Sbjct: 113 TAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGQDQ 169 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +CNGDSGGPL C + G+VSFG + C P VYT + + +WI + +Q Sbjct: 170 KDSCNGDSGGPLICN-----GYLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >4FXG-H nrPDB Length = 242 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 111/250 (44%), Gaps = 24/250 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI----SNTRTYRVA 85 + GG+ A+P +PWQ+ + T G L+ N+VLTAAH + + + Sbjct: 1 IYGGQKAKPGDFPWQVLIL------GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIR 54 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL-LRNDIALIKLAEHVELSDTIQVACLP- 143 +G + + + +H+ + NDIALIKL V ++ I CLP Sbjct: 55 MGTLKRLSPHYTQA---WSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPR 111 Query: 144 -EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATC----SRIDWWGFRVKK 198 E +S + D +GWG G +A L P+VDH C + + V Sbjct: 112 KEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTA 170 Query: 199 TMVCAGGD-GVISACNGDSGGPLN-CQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 M+CAG + G +C GD+GG L E W V GIVS+GS C + VYT+V Sbjct: 171 NMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMN-CGEAGQYGVYTKVI 229 Query: 257 AYIDWINEKM 266 YI WI + Sbjct: 230 NYIPWIENII 239 >1KYN-A nrPDB Length = 235 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 75/239 (31%), Positives = 114/239 (47%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG ++RPHS P+ LQ ++ + CGG L+ +FVLTAAHC + V +G + Sbjct: 1 IIGGRESRPHSRPYMAYLQI-QSPAGQSRCGGFLVREDFVLTAAHCWGS--NINVTLGAH 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N++ E + H ++N ++NDI L++L+ V + + LP L Sbjct: 58 NIQRR-ENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG-V 208 C V GWGR+ + D L++ V C RI +G + +C G Sbjct: 117 RPGTLCTVAGWGRV-SMRRGTDTLREVQLRVQRDRQCLRI--FGSYDPRRQICVGDRRER 173 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +A GDSGGPL C GIVS+G G P V+TRVS+++ WI M+ Sbjct: 174 KAAFKGDSGGPLLCNN-----VAHGIVSYGKSSGV----PPEVFTRVSSFLPWIRTTMR 223 >1GVZ-A nrPDB Length = 237 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 69/251 (27%), Positives = 126/251 (50%), Gaps = 30/251 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + HS PWQ+++ + CGG L+ +VLTAAHC+S+ Y++ +G++ Sbjct: 1 IIGGWECEKHSKPWQVAVYH----QGHFQCGGVLVHPQWVLTAAHCMSD--DYQIWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLL-----------RNDIALIKLAEHVELSDTIQ 138 NL +DE+ + F V + +++ LL +D+ L++LA+ ++D ++ Sbjct: 55 NLS-KDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVK 113 Query: 139 VACLPEKDSLLPKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVK 197 + LP ++ L CY +GWG + T + LQ + + C+R + ++ Sbjct: 114 ILDLPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARA--YPEKMT 169 Query: 198 KTMVCAGGDGVISA-CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 + ++CA + C GDSGG L C +G ++ GI S+G C V+T+V Sbjct: 170 EFVLCATHRDDSGSICLGDSGGALIC---DGVFQ--GITSWGYSE-CADFNDNFVFTKVM 223 Query: 257 AYIDWINEKMQ 267 + WI E ++ Sbjct: 224 PHKKWIKETIE 234 >4Q7Y-A nrPDB Length = 250 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 74/243 (30%), Positives = 117/243 (48%), Gaps = 18/243 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS--NTRTYRVAVG 87 ++GG + PHS P+ S+++ +H CGG L+ + +V++AAHC S + RT V +G Sbjct: 1 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + L E G+D + H ++ + NDI L++L L + + LP + + Sbjct: 57 AHVLSTA-EPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRA 115 Query: 148 LLP-KDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA--G 204 P C V GWG + + L + V+D C+ W + TM+C G Sbjct: 116 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRSG 173 Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264 C+ DSGGPL C+ G+VSF S C K P VYT+VSA++ WI + Sbjct: 174 DSHRRGFCSADSGGPLVCRNR-----AHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWIWD 227 Query: 265 KMQ 267 ++ Sbjct: 228 VVR 230 >1AZZ-A nrPDB Length = 226 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 80/240 (33%), Positives = 121/240 (50%), Gaps = 17/240 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGG +A P+SWP Q +L + CGG+LI+ ++LTAAHC+ V +G + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD----MYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAH 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 N+ EDE + + VH+ +N+ ++ NDIA+I+L V L+ I LP D + Sbjct: 57 NI-REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTD--V 113 Query: 150 PKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV 208 TGWG + I+D L+Q P++ +A C + V +C G Sbjct: 114 GVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY---GIVTDGNICIDSTGG 170 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 268 CNGDSGGPL N + +GI SFG+ GC P +TRV+ ++DWI + + Sbjct: 171 KGTCNGDSGGPL-----NYNGLTYGITSFGAAAGC-EAGYPDAFTRVTYFLDWIQTQTGI 224 >1OP0-A nrPDB Length = 234 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 68/239 (28%), Positives = 106/239 (44%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG + + + ++ CGGTLI +V+TAAHC ++ +++ +G + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTG----FFCGGTLINPEWVVTAAHC--DSTDFQMQLGVH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + +V +E+ + + N +L DI LIKL + + S I S Sbjct: 55 SKKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPP 112 Query: 150 PKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 C + GWG + D ++DHA C + + + +CAG G Sbjct: 113 SVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVC-QAGYPELLAEYRTLCAGIVQG 171 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C GDSGGPL C NG ++ GIVS+G+ C KP +YT V Y DWI + Sbjct: 172 GKDTCGGDSGGPLIC---NGQFQ--GIVSYGAH-PCGQGPKPGIYTNVFDYTDWIQRNI 224 >2B9L-A nrPDB Length = 394 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 72/270 (26%), Positives = 124/270 (45%), Gaps = 23/270 (8%) Query: 17 CGVPSFPPNLSARVVGGE-DARPHSWPWQISL----QYLKNDTWRHTCGGTLIASNFVLT 71 CG+ + L ++ G +A +PW +++ + + CGG+LIA + VLT Sbjct: 118 CGIRN-ERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLT 176 Query: 72 AAHCI----SNTRTYRVAVGK-NNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126 AHC+ SN ++ G+ + L ++ + + +H +N + ND+AL+ Sbjct: 177 GAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLL 236 Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRL--WTNGPIADKLQQGLQPVVDHA 184 L + +D I CLP++ + C+ +GWG+ + ++ L++ P VD Sbjct: 237 LDRPLVQADNIGTICLPQQSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRD 295 Query: 185 TCSRIDW-----WGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENG--SWEVFGIVSF 237 C F + +T VCAGG+ C GD G PL C + GIV++ Sbjct: 296 KCQADLRNTRLGLKFVLDQTFVCAGGEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAW 355 Query: 238 GSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 G GC P VY V+ + +WI+++MQ Sbjct: 356 GI--GCGDENVPGVYANVAHFRNWIDQEMQ 383 >2QY0-B nrPDB Length = 242 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 72/253 (28%), Positives = 112/253 (44%), Gaps = 29/253 (11%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI-------SNTRTY 82 ++GG+ A+ ++PWQ+ GG L+ ++LTAAH + + + Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG------GGALLGDRWILTAAHTLYPKEHEAQSNASL 54 Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN---DIALIKLAEHVELSDTIQV 139 V +G N+E + G+ + + VH + N DIAL++L V L + Sbjct: 55 DVFLGHTNVEELMKLGN--HPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLP 112 Query: 140 ACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFR---V 196 CLP+ D+ YV+G+G + IA L+ PV + C R Sbjct: 113 ICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVF 170 Query: 197 KKTMVCAGGDGVI-SACNGDSGGPLNCQLEN-GSWEVFGIVSFGSRRGCNTRKKPVVYTR 254 + M CAG + AC GDSGG + N W GIVS+G GC+ YT+ Sbjct: 171 SQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI--GCSRG--YGFYTK 226 Query: 255 VSAYIDWINEKMQ 267 V Y+DWI ++M+ Sbjct: 227 VLNYVDWIKKEME 239 >1BQY-A nrPDB Length = 234 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 108/239 (45%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V GG++ + + L ++ CGGTLI ++V+TAAHC ++ +++ G + Sbjct: 1 VFGGDECNINEHRSLVVLF----NSNGFLCGGTLINQDWVVTAAHC--DSNNFQLLFGVH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + ++ +E+ + R + DI LIKL V S+ I S Sbjct: 55 SKKILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPP 112 Query: 150 PKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 C + GWG+ T D ++DHA C W +V T +CAG G Sbjct: 113 SVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWR-QVANTTLCAGILQG 171 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C+ DSGGPL C NG ++ GIVS+G C +P VYT+V Y+DWI + Sbjct: 172 GRDTCHFDSGGPLIC---NGIFQ--GIVSWGGH-PCGQPGEPGVYTKVFDYLDWIKSII 224 >1YM0-A nrPDB Length = 238 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 70/244 (28%), Positives = 124/244 (50%), Gaps = 16/244 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRV--AVG 87 +VGG +ARP+ +PWQ+S++ +D+ H CGG++I +V+ AAHC+ V VG Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDS--HFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE-KD 146 +++ VD+I V++ ++ L ND+++IK A + + C P+ + Sbjct: 59 EHDSSAAS-TVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAN 117 Query: 147 SLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG 205 + + C +GWG + + G L+ + +A C + + + M+CA Sbjct: 118 DYVYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAV-YTSDTIYDDMICATD 174 Query: 206 DGV---ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 + +C GDSGGPL+ + +G + + GIVS+G GC + P VY+RV + WI Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI--GCAS-GYPGVYSRVGFHAGWI 231 Query: 263 NEKM 266 + + Sbjct: 232 TDTI 235 >6BQM-A nrPDB Length = 506 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 71/250 (28%), Positives = 119/250 (47%), Gaps = 17/250 (6%) Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVA 85 +S+R++GGE A WP+ ++L ++ CGG+ + +VLTAAHC+ + Sbjct: 7 VSSRIIGGEQATAGEWPYMVALTAR--NSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGD 64 Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145 V ++ D + + V I+VH + + NDIA+++L ++Q++ + Sbjct: 65 VLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDF 124 Query: 146 DSLLPKDYPCYVTGWG-RLWTNGPIAD---KLQQGLQPVVDHATCS------RIDWWGFR 195 + L D P V G+G R +G +D L Q P V C + Sbjct: 125 NELTK-DSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 196 VKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 255 + CAG G AC+GD+GGP+ NG ++ G+VS+G GC P VYT + Sbjct: 184 LTNNAFCAGSFG-KDACSGDAGGPIFFDSNNGRKQM-GVVSWGD--GCGRANSPGVYTNL 239 Query: 256 SAYIDWINEK 265 S + DW++++ Sbjct: 240 SVFNDWLDDQ 249 >3S69-A nrPDB Length = 234 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 17/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG++ + ++ ++ C GTLI +VLTAAHC + +++ +G + Sbjct: 1 VIGGDECNINEHRSLVAFF----NSTGFFCSGTLINEEWVLTAAHC--DNTNFQMKLGVH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + +V +E+ + + N +L DI LIKL V S+ I L S Sbjct: 55 SKKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSPP 112 Query: 150 PKDYPCYVTGWGRLWT-NGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 C++ GWG + D ++D A C + + + +CAG +G Sbjct: 113 SVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVC-QAGYPELLTEYRTLCAGILEG 171 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 C GDSGGPL C NG ++ GIVSFG+ C KP VYT+V Y WI + Sbjct: 172 GKDTCGGDSGGPLIC---NGQFQ--GIVSFGAH-PCGQGLKPGVYTKVFDYNHWIQSII 224 >5LPF-A nrPDB Length = 234 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 67/244 (27%), Positives = 103/244 (42%), Gaps = 27/244 (11%) Query: 33 GEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLE 92 G S PWQ+SL + C G L+ ++VLTAAHC + VG ++L Sbjct: 7 GSPCARGSQPWQVSLF----NGLSFHCAGVLVDQSWVLTAAHC--GNKPLWARVGDDHLL 60 Query: 93 VEDEEGSLFVGVDTIHVHKRWN--------ALLLRNDIALIKLAEHVELSDTIQVACLPE 144 + +G VH +++ +D+ L+KLA V L ++ LP Sbjct: 61 LL--QGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPY 118 Query: 145 KDSLLPKDYPCYVTGWGRLWTNGPIADK-LQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 203 + C V GWG +K L ++ C ++ V M+CA Sbjct: 119 R--CAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE--VFYPGVVTNNMICA 174 Query: 204 GGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 G D C DSGGPL C + GI+S+G C + + P VYT++ Y+ WIN Sbjct: 175 GLDRGQDPCQSDSGGPLVCDE-----TLQGILSWGV-YPCGSAQHPAVYTQICKYMSWIN 228 Query: 264 EKMQ 267 + ++ Sbjct: 229 KVIR 232 >1EQ9-A nrPDB Length = 222 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 86/241 (35%), Positives = 124/241 (51%), Gaps = 23/241 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTY---RVAV 86 +VGG+DA +P+Q+SL+ + H CG +++ +N VLTAAHC+ +V V Sbjct: 1 IVGGKDAPVGKYPYQVSLRL----SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHV 56 Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 146 G N L + V+ V+K ++ LLRND+AL+ L ++ +D +Q L D Sbjct: 57 GTNYLSESGD----VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTND 112 Query: 147 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD 206 L + PC +TGWG G + LQ+ V C R W RV + +C Sbjct: 113 EDLESN-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQW---RVIDSHICTLTK 168 Query: 207 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 AC+GDSGGPL NG+ GIVSFGS C +P VYTRVS+++ WIN + Sbjct: 169 RGEGACHGDSGGPLV---ANGA--QIGIVSFGS--PCAL-GEPDVYTRVSSFVSWINANL 220 Query: 267 Q 267 + Sbjct: 221 K 221 >2HLC-A nrPDB Length = 230 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 79/241 (32%), Positives = 122/241 (50%), Gaps = 15/241 (6%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++ G +A +P+Q L D R CGG+LI + ++LTAAHC+ + + V +G Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLG-- 58 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 EG V + I H +N ND+ALIK+ HVE +D IQ LP + L Sbjct: 59 --SAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIP-HVEYTDNIQPIRLPSGEELN 115 Query: 150 PKDYPCY--VTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 K + V+GWG+ T+ I LQ V+D+ C++ ++ + ++ +C Sbjct: 116 NKFENIWATVSGWGQSNTDTVI---LQYTYNLVIDNDRCAQ-EYPPGIIVESTICGDTSD 171 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 S C GDSGGP +N + G+VSF S GC KPV ++RV++Y+DWI + Sbjct: 172 GKSPCFGDSGGPFVLSDKN---LLIGVVSFVSGAGC-ESGKPVGFSRVTSYMDWIQQNTG 227 Query: 268 L 268 + Sbjct: 228 I 228 >4LK4-A nrPDB Length = 357 Score = 215 bits (548), Expect = 1e-56, Method: Composition-based stats. Identities = 67/248 (27%), Positives = 109/248 (43%), Gaps = 16/248 (6%) Query: 24 PNLSARVVGGEDARPHSWPWQISLQYLKNDTWR-HTCGGTLIASNFVLTAAHCISNTRTY 82 ++S+R++ G +A WP ++L D ++ CGG+ + +VLTAAHC + Sbjct: 5 ADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAA 64 Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142 V V ++ + + I+ H ++ L NDIA+++LA+ + ++ L Sbjct: 65 SVDVIIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQ----TSSLPAITL 120 Query: 143 --PEKDSLLPKDYPCYVTGWGRLWTNGP--IADKLQQGLQPVVDHATCSRIDWWGFRVKK 198 P + LP P V GWG + P LQ+ +V + C + G Sbjct: 121 AGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDP 180 Query: 199 T--MVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 256 CA +C GD+GGP+ + E GIVS+G + C VYT VS Sbjct: 181 NSTNFCA-ARLTKDSCQGDAGGPIVVKTGR---EQLGIVSWGDEQ-CAKTGTYGVYTNVS 235 Query: 257 AYIDWINE 264 + DWI + Sbjct: 236 YFRDWITK 243 >3I77-A nrPDB Length = 230 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 69/235 (29%), Positives = 96/235 (40%), Gaps = 14/235 (5%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG A +P+ + L +N+ CGG L A + VLTAAHC+S + Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEG---FCGGALYAQDIVLTAAHCVSGSGNNTSITATG 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + ++ V + + D ALIKLA+ + T+++A + Sbjct: 58 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPIN-QPTLKIATTTAYNQG- 115 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD--G 207 V GWG G L + P V A C + V M+CAG G Sbjct: 116 ----TFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF-ILVANEMICAGYPDTG 170 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 + C GDSGGP+ + W GIVS+G GC P VYT VS + I Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWG--YGCARPGYPGVYTEVSTFASAI 223 >4WJG-C nrPDB Length = 315 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 76/286 (26%), Positives = 113/286 (39%), Gaps = 53/286 (18%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C + CG P P N R++GG S+PWQ + N T G TLI ++ Sbjct: 51 LPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHN----LTTGATLINEQWL 106 Query: 70 LTAAHCISNTR-----------TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 LT A + T + VGK V ++ + +H ++ + Sbjct: 107 LTTAKNLFLNHSENATAKDIAPTLTLYVGK----------KQLVEIEKVVLHPNYSQV-- 154 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178 DI LIKL + V +++ + CLP KD YV+GWGR N D L+ + Sbjct: 155 --DIGLIKLKQKVSVNERVMPICLPSKDY-AEVGRVGYVSGWGRN-ANFKFTDHLKYVML 210 Query: 179 PVVDHATCSRIDWWGFRVKKT----------------MVCAG-GDGVISACNGDSGGPLN 221 PV D C R + G V + CAG C GD+G Sbjct: 211 PVADQDQCIR-HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFA 269 Query: 222 CQL-ENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 E +W GI+SF + C + VY +V++ DW+ + + Sbjct: 270 VHDLEEDTWYATGILSF--DKSCAVAE-YGVYVKVTSIQDWVQKTI 312 >5XRF-A nrPDB Length = 242 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 66/244 (27%), Positives = 101/244 (41%), Gaps = 15/244 (6%) Query: 25 NLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRV 84 S V+GG + + + + + + W C GTLI +VL AAHC R + Sbjct: 2 KSSELVIGGNECDTNEHRFLAA--FFTSRPWTFQCAGTLIHEEWVLAAAHCYK--RGLNI 57 Query: 85 AVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE 144 +G +N ++ ++ ++ + D+ L+KL + V S I Sbjct: 58 YLGMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--L 115 Query: 145 KDSLLPKDYPCYVTGWGRL-WTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 203 S C V GWG + T + D ++++ C + ++CA Sbjct: 116 PSSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECV-AHYPDVPETTRLLCA 174 Query: 204 G-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 G +G I CN DSGGPL C + GIV FG + C KP +YTRVS Y DWI Sbjct: 175 GVLEGGIDTCNQDSGGPLICD-----GQFQGIVFFG-KYPCAQPNKPGLYTRVSNYNDWI 228 Query: 263 NEKM 266 + Sbjct: 229 QNII 232 >4F4O-C nrPDB Length = 347 Score = 210 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 76/286 (26%), Positives = 115/286 (40%), Gaps = 53/286 (18%) Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69 L C + CG P P + R++GG S+PWQ + N T G TLI ++ Sbjct: 83 LPECEAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHN----LTSGATLINEQWL 138 Query: 70 LTAAHCISNTR-----------TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 LT A + T R+ VGK V ++ + H + + Sbjct: 139 LTTAKNLRLGHKNDTKAKDIAPTLRLYVGK----------KQEVEIEKVIFHPDNSTV-- 186 Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178 DI LIKL + V +++ + CLP KD + YV+GWGR N + L+ + Sbjct: 187 --DIGLIKLKQKVPVNERVMPICLPSKDY-VNVGLVGYVSGWGRN-ANLNFTEHLKYVML 242 Query: 179 PVVDHATCSRIDWWGFRVKKT----------------MVCAG-GDGVISACNGDSGGPLN 221 PV D C + + G V + CAG C GD+G Sbjct: 243 PVADQEKCVQ-YYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFA 301 Query: 222 CQLE-NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + + +W GI+SF + C T + VY RV++ +DWI + Sbjct: 302 VHDKDDDTWYAAGILSF--DKSCRTAE-YGVYVRVTSILDWIQTTI 344 >2ASU-B nrPDB Length = 234 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 114/245 (46%), Gaps = 24/245 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR----TYRVA 85 VVGG P + PW +SL +N +H CGG+L+ ++LTA C S+ Y V Sbjct: 1 VVGGH---PGNSPWTVSL---RNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVW 54 Query: 86 VGKNNLEVED-EEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPE 144 +G + E V V + + + L+KL V L+ + + CLP Sbjct: 55 LGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQ------LVLLKLERSVTLNQRVALICLPP 108 Query: 145 KDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA- 203 + ++P C + GWG G L L V+ + C+ RV+++ +C Sbjct: 109 EWYVVPPGTKCEIAGWGETKGTGNDT-VLNVALLNVISNQECNIKH--RGRVRESEMCTE 165 Query: 204 GGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 G + AC GD GGPL C N SW + GI+ R C + P V+TRVS ++DWI+ Sbjct: 166 GLLAPVGACEGDYGGPLACFTHN-SWVLEGII--IPNRVCARSRWPAVFTRVSVFVDWIH 222 Query: 264 EKMQL 268 + M+L Sbjct: 223 KVMRL 227 >5KWM-A nrPDB Length = 230 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 108/239 (45%), Gaps = 19/239 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +VGGEDA P+ ++L + CGGTL A N V+TAAHC ++ + V Sbjct: 1 IVGGEDANVQDHPFTVALVTPD---GQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSG 57 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS-L 148 + EG++ V + VH + D++++ L V+ L + D Sbjct: 58 RTVMSSNEGTV-SKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAG 112 Query: 149 LPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 207 D + GWG G AD LQ+ PV TC + +G MVCAG +G Sbjct: 113 YAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQA--YGEYTPDAMVCAGVPEG 170 Query: 208 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + C GDSGGP+ + + G+ S+G GC KP VY RV AY D + E++ Sbjct: 171 GVDTCQGDSGGPMVVNNK-----LIGVTSWG--EGCARPGKPGVYARVGAYYDVLMEQI 222 >3BEU-A nrPDB Length = 224 Score = 206 bits (525), Expect = 6e-54, Method: Composition-based stats. Identities = 68/234 (29%), Positives = 93/234 (39%), Gaps = 18/234 (7%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG A +P+ + L CGG L A + VLTAAHC+S + Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + ++ V + + D ALIKLA+ + T+++A + Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPIN-QPTLKIATTTAYNQG- 110 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVI 209 V GWG G L + P V A C + V M+CAG D Sbjct: 111 ----TFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF-ILVANEMICAGYDTKQ 165 Query: 210 -SACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 C GDSGGP+ + W GIVS+G GC + K VYT VS + I Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGIVSWG--EGCARKGKYGVYTEVSTFASAI 217 >4X0L-C nrPDB Length = 259 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 74/280 (26%), Positives = 110/280 (39%), Gaps = 53/280 (18%) Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75 CG P P N R++GG S+PWQ + N T G TLI ++LT A Sbjct: 1 VCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHN----LTTGATLINEQWLLTTAKN 56 Query: 76 ISNTR-----------TYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIAL 124 + T + VGK V ++ + +H ++ + DI L Sbjct: 57 LFLNHSENATAKDIAPTLTLYVGK----------KQLVEIEKVVLHPNYSQV----DIGL 102 Query: 125 IKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHA 184 IKL + V +++ + CLP KD YV+GWGR N D L+ + PV D Sbjct: 103 IKLKQKVSVNERVMPICLPSKDY-AEVGRVGYVSGWGRN-ANFKFTDHLKYVMLPVADQD 160 Query: 185 TCSRIDWWGFRVKKT----------------MVCAG-GDGVISACNGDSGGPLNCQL-EN 226 C R + G V + CAG C GD+G E Sbjct: 161 QCIR-HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEE 219 Query: 227 GSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +W GI+SF + C + VY +V++ DW+ + + Sbjct: 220 DTWYATGILSF--DKSCAVAE-YGVYVKVTSIQDWVQKTI 256 >1AE5-A nrPDB Length = 225 Score = 203 bits (518), Expect = 4e-53, Method: Composition-based stats. Identities = 63/240 (26%), Positives = 103/240 (42%), Gaps = 26/240 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT--YRVAVG 87 +VGG ARP +P+ S+Q + RH CGG LI + FV+TAA C + V +G Sbjct: 1 IVGGRKARPRQFPFLASIQ----NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +L + + + ++ ++ ND+ L++L L+ ++ + LP +++ Sbjct: 57 AYDLRRRERQSRQTFSISSMSE-NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA 115 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 + C V GWG + G ++ + V C + VC G Sbjct: 116 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCTGVLT 165 Query: 208 VISA-CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 CNGD G PL C+ G+ SF S C P +TRV+ + DWI+ + Sbjct: 166 RRGGICNGDGGTPLVCE-----GLAHGVASF-SLGPCGRG--PDFFTRVALFRDWIDGVL 217 >1PPF-E nrPDB Length = 218 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 84/241 (34%), Positives = 115/241 (47%), Gaps = 26/241 (10%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC--ISNTRTYRVAVG 87 +VGG ARPH+WP+ +SLQ H CG TLIA NFV++AAHC N R RV +G Sbjct: 1 IVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 +NL E V I ++ + L NDI +++L ++ +QVA LP + Sbjct: 57 AHNLSRR-EPTRQVFAVQRIFE-NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 114 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 207 L C GWG L N IA LQ+ VV + C R + VC G Sbjct: 115 RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSN----------VCTLVRG 163 Query: 208 VISA-CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + C GDSG PL C + GI SF R GC + P + V+ +++WI+ + Sbjct: 164 RQAGVCFGDSGSPLVCN-----GLIHGIASF-VRGGCASGLYPDAFAPVAQFVNWIDSII 217 Query: 267 Q 267 Q Sbjct: 218 Q 218 >1PQ7-A nrPDB Length = 224 Score = 200 bits (508), Expect = 8e-52, Method: Composition-based stats. Identities = 68/238 (28%), Positives = 104/238 (43%), Gaps = 21/238 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN--TRTYRVAVG 87 +VGG A +P+ +S+ + CGG+L+ +N VLTAAHC+S +++ G Sbjct: 1 IVGGTSASAGDFPFIVSI----SRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG 56 Query: 88 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + G + + ++ VH ++ ND+A++KL+ + I A L S Sbjct: 57 ----SLSRTSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGS 110 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADK-LQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 205 V GWG G L + P+V ATC R + + M CAG Sbjct: 111 DPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATC-RAQYGTSAITNQMFCAGVS 169 Query: 206 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 G +C GDSGGP+ + S + G VS+G GC VY V A +I+ Sbjct: 170 SGGKDSCQGDSGGPIV----DSSNTLIGAVSWG--NGCARPNYSGVYASVGALRSFID 221 >2FMJ-A nrPDB Length = 222 Score = 198 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 70/234 (29%), Positives = 96/234 (41%), Gaps = 20/234 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 VVGG A +P+ + L CGG L A + VLTAAHC+S + Sbjct: 1 VVGGTRAAQGEFPFMVRL--------SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATG 52 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + ++ V + +N D ALIKLA+ + T+++A + Sbjct: 53 GVVDLQSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLAQPIN-QPTLKIATTTAYNQG- 108 Query: 150 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD-GV 208 V GWG G L + P V A C R + V +CAG D G Sbjct: 109 ----TFTVAGWGANREGGSQQRYLLKANVPFVSDAAC-RSAYGNELVANEEICAGYDTGG 163 Query: 209 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262 + C GDSGGP+ + W GIVS+G GC + K VYT VS + I Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGIVSWG--EGCARKGKYGVYTEVSTFASAI 215 >1SI5-H nrPDB Length = 240 Score = 197 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 61/228 (26%), Positives = 101/228 (44%), Gaps = 18/228 (7%) Query: 43 WQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--SNTRTYRVAVGKNNLEVE-DEEGS 99 W +SL+Y +H CGG+LI ++VLTA C + + Y +G +++ DE+ Sbjct: 13 WMVSLRYRN----KHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCK 68 Query: 100 LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTG 159 + V + +D+ L+KLA L D + LP S +P+ C V G Sbjct: 69 QVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYG 122 Query: 160 WGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG-VISACNGDSGG 218 WG L+ ++ + CS+ + ++ +CAG + C GD GG Sbjct: 123 WGYTGLI-NYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGG 181 Query: 219 PLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 PL C+ + IV RGC +P ++ RV+ Y WI++ + Sbjct: 182 PLVCEQHKMRMVLGVIV---PGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >1M9U-A nrPDB Length = 241 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 82/243 (33%), Positives = 122/243 (50%), Gaps = 10/243 (4%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 V+GG +A P +PWQ+S Q ++ +W H+CG +L++S L+A+HC+ + V Sbjct: 1 VIGGTNASPGEFPWQLS-QQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG 59 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALL--LRNDIALIKLAEHVELSDTIQVACLPEKDS 147 + D G+ VD+ +H+ + A NDIA++ LA + L IQ A LP ++ Sbjct: 60 LWQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNN 119 Query: 148 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR--IDWWGFRVKKTMVCAGG 205 C ++GWGR + D LQ+ PV+ A C+ + G + +C Sbjct: 120 NDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQD 179 Query: 206 D-GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT--RKKPVVYTRVSAYIDWI 262 G ACNGDSGGPLNC +G V G+ S+ G P VYTRVSAY+ WI Sbjct: 180 PAGNTGACNGDSGGPLNC--PDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 Query: 263 NEK 265 + Sbjct: 238 GDN 240 >3H7O-A nrPDB Length = 228 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 58/237 (24%), Positives = 109/237 (45%), Gaps = 13/237 (5%) Query: 32 GGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNL 91 GGE PW ++++ + TCGG +++ FVLTAAHC+ + + + + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEE-SLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYEST 60 Query: 92 EVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSD-TIQVACLPEKDSLLP 150 + ++ G V +++ + + NDIA+++L+ ++L + A LP+ + Sbjct: 61 NLWEDPGKSDPYVSHVYL-SFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 151 KDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVIS 210 V+G+G T P L+ VVD C R + + + CA GV S Sbjct: 120 TGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDEC-RTKYGPIFLSLQVFCAQKVGV-S 177 Query: 211 ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 +GD+G P Q + G+ ++ +R P V+T+V +Y+ WI + ++ Sbjct: 178 LESGDAGDPTVQQD-----TLVGVAAYFPKRP---EGAPEVFTKVGSYVSWIQDIIK 226 >5XW8-A nrPDB Length = 133 Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats. Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 10/143 (6%) Query: 22 FPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT 81 FP + ++VGG +S P+Q+SL ++ H CGG+LI S +V++AAHC + Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-----NSGSHFCGGSLINSQWVVSAAHCYKSR-- 53 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVAC 141 +V +G++N++V E F+ I H +N L NDI LIKL+ L+ + Sbjct: 54 IQVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 112 Query: 142 LPEKDSLLPKDYPCYVTGWGRLW 164 LP S C ++GWG Sbjct: 113 LPR--SCAAAGTECLISGWGNTK 133 >2PKA-B nrPDB Length = 152 Score = 167 bits (424), Expect = 4e-42, Method: Composition-based stats. Identities = 47/157 (29%), Positives = 81/157 (51%), Gaps = 14/157 (8%) Query: 114 NALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWT---NGPIA 170 + +D+ L++L +++D ++V LP ++ L C +GWG + + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 171 DKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSW 229 D++Q ++ + C D +V ++M+CAG G C GDSGGPL C NG W Sbjct: 60 DEIQCVQLTLLQNTFC--ADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLIC---NGMW 114 Query: 230 EVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + GI S+G C + KP +YT++ Y+DWI++ + Sbjct: 115 Q--GITSWG-HTPCGSANKPSIYTKLIFYLDWIDDTI 148 >3VGC-B nrPDB Length = 131 Score = 161 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 49/135 (36%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 +V GE+A P SWPWQ+SLQ + T H CGG+LI N+V+TAAHC T V V Sbjct: 1 IVNGEEAVPGSWPWQVSLQ---DKTGFHFCGGSLINENWVVTAAHC--GVTTSDVVVAGE 55 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 149 + E + + + + ++N+L + NDI L+KL+ S T+ CLP Sbjct: 56 FDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDF 115 Query: 150 PKDYPCYVTGWGRLW 164 C TGWG Sbjct: 116 AAGTTCVTTGWGLTR 130 >2JET-B nrPDB Length = 128 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 53/132 (40%), Positives = 74/132 (56%), Gaps = 5/132 (3%) Query: 33 GEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLE 92 GEDA P SWPWQ+SLQ + T H CGG+LI+ ++V+TAAHC +T V V + Sbjct: 1 GEDAIPGSWPWQVSLQ---DKTGFHFCGGSLISEDWVVTAAHC--GVKTSDVVVAGEFDQ 55 Query: 93 VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKD 152 DEE + + + + ++N +RNDI L+KLA + S+T+ CLP D P Sbjct: 56 GSDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPG 115 Query: 153 YPCYVTGWGRLW 164 C TGWG+ Sbjct: 116 TVCATTGWGKTK 127 >2WIN-I nrPDB Length = 507 Score = 160 bits (405), Expect = 5e-40, Method: Composition-based stats. Identities = 58/280 (20%), Positives = 101/280 (36%), Gaps = 58/280 (20%) Query: 36 ARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVED 95 H PWQ + ++ +C G +++ FVLTAAHC + +++++V Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK------EHSIKVSV 282 Query: 96 EEGSLFVGVDTIHVHKRWN---------ALLLRNDIALIKLAEHVELSDTIQVACLP--- 143 + ++ + H +N D+ALIKL ++ TI+ CLP Sbjct: 283 GGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTE 342 Query: 144 --EKDSLLPKDYPC----------------YVTGWGRLWT-------NGPIADKLQQGLQ 178 + LP C +V+ + T NG ++ Q Sbjct: 343 GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 402 Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVI---SACNGDSGGPLNCQLENGSWEVFGIV 235 + I V +C GG + C GDSGGPL + + G++ Sbjct: 403 YAPGYDKVKDIS---EVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS-RFIQVGVI 458 Query: 236 SFGSRRGCNTRKKP--------VVYTRVSAYIDWINEKMQ 267 S+G C +K+ + + + W+ EK+Q Sbjct: 459 SWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 498 >1RIW-B nrPDB Length = 147 Score = 160 bits (405), Expect = 7e-40, Method: Composition-based stats. Identities = 50/149 (33%), Positives = 71/149 (47%), Gaps = 14/149 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + ++ I++H R+N L DIAL+KL + V SD I Sbjct: 59 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 118 Query: 141 CLPEKD---SLLPKDYPCYVTGWGRLWTN 166 CLP+++ SLL Y VTGWG L Sbjct: 119 CLPDRETAASLLQAGYKGRVTGWGNLKET 147 >3H7T-A nrPDB Length = 235 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 56/243 (23%), Positives = 107/243 (44%), Gaps = 21/243 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG+ + PW + + + CGG+++ +NFV+TAA C+ T+ +++ Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKP----FCGGSILTANFVITAAQCVDGTKPSDISIHYG 56 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSD-TIQVACLPEKDSL 148 + + S+ I R++ L ++N+ A+I+ ++L D T + LP Sbjct: 57 SSYRTTKGTSVMAKKIYIV---RYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYD 113 Query: 149 LPKDYPCYVTGWGRL-WTNGPIADKLQQGLQPVVDHATCSRIDWW---GFRVKKTMVCAG 204 D V+GWG + + + L + VVD +C + + CAG Sbjct: 114 PEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAG 173 Query: 205 GDGVISAC-NGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263 G+ + GD+G P +NG+ + G+ S+ S + P V+ RV Y+ I Sbjct: 174 GEYDETYIGYGDAGDPAV---QNGT--LVGVASYISSMP---SEFPSVFLRVGYYVLDIK 225 Query: 264 EKM 266 + + Sbjct: 226 DII 228 >1DLE-A nrPDB Length = 298 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 58/280 (20%), Positives = 101/280 (36%), Gaps = 58/280 (20%) Query: 36 ARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVED 95 H PWQ + ++ +C G +++ FVLTAAHC + +++++V Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK------EHSIKVSV 75 Query: 96 EEGSLFVGVDTIHVHKRWN---------ALLLRNDIALIKLAEHVELSDTIQVACLP--- 143 + ++ + H +N D+ALIKL ++ TI+ CLP Sbjct: 76 GGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTE 135 Query: 144 --EKDSLLPKDYPC----------------YVTGWGRLWT-------NGPIADKLQQGLQ 178 + LP C +V+ + T NG ++ Q Sbjct: 136 GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 195 Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVI---SACNGDSGGPLNCQLENGSWEVFGIV 235 + I V +C GG + C GDSGGPL + + G++ Sbjct: 196 YAPGYDKVKDIS---EVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS-RFIQVGVI 251 Query: 236 SFGSRRGCNTRKKP--------VVYTRVSAYIDWINEKMQ 267 S+G C +K+ + + + W+ EK+Q Sbjct: 252 SWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >1BBR-H nrPDB Length = 150 Score = 156 bits (395), Expect = 8e-39, Method: Composition-based stats. Identities = 50/149 (33%), Positives = 72/149 (48%), Gaps = 14/149 (9%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G+DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGQDAEVGLSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 58 Query: 82 YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVA 140 V +GK++ + + +D I++H R+N L DIAL+KL +ELSD I Sbjct: 59 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 118 Query: 141 CLPEKDS---LLPKDYPCYVTGWGRLWTN 166 CLP+K + LL + VTGWG Sbjct: 119 CLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2OK5-A nrPDB Length = 752 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 58/280 (20%), Positives = 101/280 (36%), Gaps = 58/280 (20%) Query: 36 ARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVED 95 H PWQ + ++ +C G +++ FVLTAAHC + +++++V Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK------EHSIKVSV 526 Query: 96 EEGSLFVGVDTIHVHKRWN---------ALLLRNDIALIKLAEHVELSDTIQVACLP--- 143 + ++ + H +N D+ALIKL ++ TI+ CLP Sbjct: 527 GGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTE 586 Query: 144 --EKDSLLPKDYPC----------------YVTGWGRLWT-------NGPIADKLQQGLQ 178 + LP C +V+ + T NG ++ Q Sbjct: 587 GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 646 Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVI---SACNGDSGGPLNCQLENGSWEVFGIV 235 + I V +C GG + C GDSGGPL + + G++ Sbjct: 647 YAPGYDKVKDIS---EVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS-RFIQVGVI 702 Query: 236 SFGSRRGCNTRKKP--------VVYTRVSAYIDWINEKMQ 267 S+G C +K+ + + + W+ EK+Q Sbjct: 703 SWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >3F1S-B nrPDB Length = 283 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 59/228 (25%), Positives = 95/228 (41%), Gaps = 20/228 (8%) Query: 42 PWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLF 101 PWQ+ L N + CGG +I NFVLT A C R V N + L Sbjct: 65 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFN----RTSQDPLM 117 Query: 102 VGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD---SLLPKDYPCYVT 158 + + +HVH R++A ND++L++L ++ C PEKD LL ++ Sbjct: 118 IKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLS 177 Query: 159 GWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGG 218 GW R T+ + + L +V+ C ++ V T ++A + G Sbjct: 178 GWARNGTD--LGNSLTTRPVTLVEGEECGQV----LNVTVTTRTYCERSSVAAMHWMDGS 231 Query: 219 PLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + + GSW + G++ G + V+ T+VS Y W + M Sbjct: 232 -VVTREHRGSWFLTGVLGSQPVGG---QAHMVLVTKVSRYSLWFKQIM 275 >2I6S-A nrPDB Length = 517 Score = 146 bits (369), Expect = 8e-36, Method: Composition-based stats. Identities = 65/302 (21%), Positives = 109/302 (36%), Gaps = 71/302 (23%) Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75 CGV + N S + PW ++++ + TC G LI+ +VLTAAHC Sbjct: 227 ICGVGNMSANASDQ---------ERTPWHVTIK----PKSQETCRGALISDQWVLTAAHC 273 Query: 76 ISNTRT---YRVAVGKNN----LEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLA 128 + +RV VG E E+ + G D + +DIAL+KLA Sbjct: 274 FRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLA 333 Query: 129 EHVELSDTIQVACLPEKDSLL-----PKDYPCYVTGWGRLWTNGPI-------------A 170 + V++S + CLP P+ C R N + Sbjct: 334 QKVKMSTHARPICLPCTMEANLALRRPQGSTC------RDHENELLNKQSVPAHFVALNG 387 Query: 171 DKLQQGLQPVVDHATCSRIDWWGFR-----------VKKTMVCAGGDGVISACNGDSGGP 219 KL L+ V+ +C+ + V +C+G S C G+SGG Sbjct: 388 SKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGA 447 Query: 220 LNCQLENGSWEVFGIVSFGSRRGC-------NTRKKP--------VVYTRVSAYIDWINE 264 + + ++V G+VS+G C + ++ P + + W+ + Sbjct: 448 VFLERRFRFFQV-GLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQ 506 Query: 265 KM 266 + Sbjct: 507 HL 508 >3H5C-B nrPDB Length = 317 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 59/228 (25%), Positives = 95/228 (41%), Gaps = 20/228 (8%) Query: 42 PWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLF 101 PWQ+ L N + CGG +I NFVLT A C R V N + L Sbjct: 106 PWQVKL---TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFN----RTSQDPLM 158 Query: 102 VGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD---SLLPKDYPCYVT 158 + + +HVH R++A ND++L++L ++ C PEKD LL ++ Sbjct: 159 IKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLS 218 Query: 159 GWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGG 218 GW R T+ + + L +V+ C ++ V T ++A + G Sbjct: 219 GWARNGTD--LGNSLTTRPVTLVEGEECGQV----LNVTVTTRTYCERSSVAAMHWMDGS 272 Query: 219 PLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 + + GSW + G++ G + V+ T+VS Y W + M Sbjct: 273 -VVTREHRGSWFLTGVLGSQPVGG---QAHMVLVTKVSRYSLWFKQIM 316 >1AKS-B nrPDB Length = 98 Score = 124 bits (311), Expect = 5e-29, Method: Composition-based stats. Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 10/104 (9%) Query: 164 WTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNC 222 + LQ PV+ +++C + ++ M+C G G +C GDSGGP+ C Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSS--YPGQITGNMICVGFLQGGKDSCQGDSGGPVVC 58 Query: 223 QLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 ++ GIVS+G GC + KP VYT+V Y++WI + + Sbjct: 59 N-----GQLQGIVSWG--YGCAQKNKPGVYTKVCNYVNWIQQTI 95 >2HNT-F nrPDB Length = 105 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 9/103 (8%) Query: 169 IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQL 224 LQ P+V+ C D R+ M CAG +G AC GDSGGP + Sbjct: 2 QPSVLQVVNLPIVERPVCK--DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKS 59 Query: 225 E-NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 N W GIVS+G GC+ K YT V WI + + Sbjct: 60 PFNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRLKKWIQKVI 100 >1BBR-E nrPDB Length = 109 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 9/103 (8%) Query: 169 IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG---GDGVI-SACNGDSGGPLNCQL 224 LQ P+V+ C R+ M CAG G+G AC GDSGGP + Sbjct: 6 QPSVLQVVNLPLVERPVCKAST--RIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKS 63 Query: 225 E-NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 N W GIVS+G GC+ K YT V WI + + Sbjct: 64 PYNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRLKKWIQKVI 104 >3RU4-E nrPDB Length = 96 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 43/99 (43%), Positives = 65/99 (65%), Gaps = 6/99 (6%) Query: 168 PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENG 227 D+LQQ P++ + C + +WG ++K M+CAG GV S+C GDSGGPL C+ +NG Sbjct: 1 NTPDRLQQASLPLLSNTNCKK--YWGTKIKDAMICAGASGV-SSCMGDSGGPLVCK-KNG 56 Query: 228 SWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 +W + GIVS+GS C+T P VY RV+A ++W+ + + Sbjct: 57 AWTLVGIVSWGSST-CSTS-TPGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 42/99 (42%), Positives = 60/99 (60%), Gaps = 6/99 (6%) Query: 169 IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGS 228 +KLQQ P+V A C + WG ++ M CAG GV +C GDSGGPL CQ ++G Sbjct: 5 TPEKLQQAALPIVSEADCKKS--WGSKITDVMTCAGASGV-DSCMGDSGGPLVCQ-KDGV 60 Query: 229 WEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267 W + GIVS+GS G + P VY+RV+A + W+ + ++ Sbjct: 61 WTLAGIVSWGS--GVCSTSTPGVYSRVTALMPWVQQILE 97 >2KAI-A nrPDB Length = 80 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 7/85 (8%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 89 ++GG + +S PWQ+++ + + CGG L+ +VLTAAHC Y V +G++ Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSS----FQCGGVLVNPKWVLTAAHC--KNDNYEVWLGRH 54 Query: 90 NLEVEDEEGSLFVGVDTIHVHKRWN 114 NL E+E + F GV H +N Sbjct: 55 NL-FENENTAQFFGVTADFPHPGFN 78 >1EPT-B nrPDB Length = 82 Score = 99 bits (248), Expect = 9e-22, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 3/85 (3%) Query: 80 RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQV 139 +V +G++N++V E F+ I H +N L NDI LIKL+ L+ + Sbjct: 1 SRIQVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVAT 59 Query: 140 ACLPEKDSLLPKDYPCYVTGWGRLW 164 LP S C ++GWG Sbjct: 60 VSLPR--SCAAAGTECLISGWGNTK 82 >2HNT-E nrPDB Length = 81 Score = 81.5 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%) Query: 99 SLFVGVDTIHVHKRWN-ALLLRNDIALIKLAEHVELSDTIQVACLPEKD---SLLPKDYP 154 ++ I++H R+N L DIAL+KL + V SD I CLP+++ SLL Y Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 155 CYVTGWGRLWTN 166 VTGWG L Sbjct: 63 GRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 80.7 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 10/72 (13%) Query: 30 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCI--------SNTRT 81 +V G DA PWQ+ L + CG +LI+ +VLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVML--FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 58 Query: 82 YRVAVGKNNLEV 93 V +GK++ Sbjct: 59 LLVRIGKHSRTR 70 >1P3E-A nrPDB Length = 215 Score = 41.0 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 61/187 (32%), Gaps = 36/187 (19%) Query: 55 WRHTCGGTLIASNFVLTAAHCISNTRT------YRVAVGKNNLEVEDEEGSLFVGVDTIH 108 +C GTLIA N +LT HC+ NT + V G N+ + + + Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSA----NMTEFY 83 Query: 109 VHKRW-NALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNG 167 V + N + D A+IK + +T+ + + +L ++G Sbjct: 84 VPSGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNL--TGTTIKISG-------- 131 Query: 168 PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENG 227 + V + + + +G+SG + + Sbjct: 132 -YPGDKMRSTGKVSQWEMSGSVTREDTNLAYYTI--------DTFSGNSGSAML----DQ 178 Query: 228 SWEVFGI 234 + ++ G+ Sbjct: 179 NQQIVGV 185 >4JCN-A nrPDB Length = 216 Score = 33.3 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 34/195 (17%), Positives = 67/195 (34%), Gaps = 38/195 (19%) Query: 45 ISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR--TYRVAVGKNNLEVEDEEGSLFV 102 +S Y+ D + G ++ N +LT H ++ + ++V + D FV Sbjct: 22 VSFIYIPIDGGYMSGSGVVVGENEILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFV 81 Query: 103 GVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP---EKDSLLPKDYPCYVTG 159 G I + +D+A+++++ E + I P ++ + VTG Sbjct: 82 G-QEIIPYPG------NSDLAILRVS-PNEHNQHIGQVVKPATISSNTDTRINENITVTG 133 Query: 160 WGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGP 219 + G + ++ + G +S G+SG P Sbjct: 134 Y-----PGDKPLATM--------WESVGKVVYIGGE--------ELRYDLSTVGGNSGSP 172 Query: 220 LNCQLENGSWEVFGI 234 + NG +V GI Sbjct: 173 VF----NGKNQVIGI 183 >2QY0-A nrPDB Length = 159 Score = 33.3 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 6/20 (30%), Positives = 7/20 (35%) Query: 10 LLACASSCGVPSFPPNLSAR 29 + C CG P P R Sbjct: 140 IPRCLPVCGKPVNPVEQRQR 159 >3MH6-A nrPDB Length = 456 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 60/179 (33%), Gaps = 49/179 (27%) Query: 61 GTLIASN--FVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 G +I ++ +V+T H + N +V + + R Sbjct: 90 GVIIDADKGYVVTNNHVVDNATVIKVQL----------SDGRKFDAKMVGKDPRS----- 134 Query: 119 RNDIALIKLAEHVELSDTIQVAC---LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQ 175 DIALI++ L+ I++A L D + P G G T+G ++ Sbjct: 135 --DIALIQIQNPKNLT-AIKMADSDALRVGDYTVAIGNPF---GLGETVTSGIVSA---- 184 Query: 176 GLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGI 234 + + + ++ F + G+SGG L N + E+ GI Sbjct: 185 -----LGRSGLNAENYENFIQTDAAIN----------RGNSGGALV----NLNGELIGI 224 >5ILB-A nrPDB Length = 474 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 31/92 (33%), Gaps = 22/92 (23%) Query: 34 EDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEV 93 A +S PWQ K + T +I +LT AHC+ + +V Sbjct: 17 HTAPDYSLPWQ------KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVK-------- 62 Query: 94 EDEEGSLFVGVDTIHVHKRWNALLLRNDIALI 125 G V + V + DIAL+ Sbjct: 63 --RRGDDRKYVAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 31/92 (33%), Gaps = 22/92 (23%) Query: 34 EDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEV 93 A +S PWQ K + T +I +LT AHC+ + +V Sbjct: 57 HTAPDYSLPWQ------KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVK-------- 102 Query: 94 EDEEGSLFVGVDTIHVHKRWNALLLRNDIALI 125 G V + V + DIAL+ Sbjct: 103 --RRGDDRKYVAKVLV------RGVDCDIALL 126 >1DUE-A nrPDB Length = 242 Score = 31.4 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 48/144 (33%), Gaps = 13/144 (9%) Query: 61 GTLIASNFVLTAAHC--ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118 G LI N VLT H +N +V+ + ++ +D + + Sbjct: 59 GVLIGKNTVLTNRHIAKFANGDPSKVSF-RPSINTDDNGNTETPYGEYEVKEILQEPFGA 117 Query: 119 RNDIALIKLAEH---VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQ 175 D+ALI+L V L D I A + + L D + G + + + Sbjct: 118 GVDLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLELI---GYPFDHKVNQMHRSE 174 Query: 176 GLQPVVDHATCSRIDWWGFRVKKT 199 + + ++GF V Sbjct: 175 IELTTLSR----GLRYYGFTVPGN 194 >3H7V-A nrPDB Length = 330 Score = 31.0 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 33/91 (36%), Gaps = 13/91 (14%) Query: 70 LTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAE 129 LT A +R G L +EDE+G + G I W + L DIAL + Sbjct: 16 LTTA-----QGVWRSRSGIY-LRLEDEQGQVGYG--EIAPLPGWGSETLNADIALCQ--- 64 Query: 130 HVELSDTIQVACLPEKDSLLPKDYPCYVTGW 160 +L + + LP + T W Sbjct: 65 --QLPGHLTPEIMATIPEALPAAQFGFATAW 93 >3SZE-A nrPDB Length = 968 Score = 30.6 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 20/57 (35%), Gaps = 9/57 (15%) Query: 211 ACNGDSGGPLNC-QLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266 A GD+G L + W V G V +G N + +AY W + Sbjct: 203 ASQGDAGSALFVYDNQKKKWVVAGTV-WGIYNYANGKNH-------AAYSKWNQTTI 251 >3LT3-A nrPDB Length = 217 Score = 30.6 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 42 PWQISLQYLKNDTWRHTCG-GTLIASNFVLTAAHCISNTRTYRVAVGK 88 P + ++ L + G G +I+ + V+T AH ++ + V G Sbjct: 22 PSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTVYAGD 69 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 14/26 (53%), Gaps = 4/26 (15%) Query: 210 SACNGDSGGPLNCQLENGSWEVFGIV 235 GD+GGPL NG +V G+V Sbjct: 157 DVEQGDAGGPLI--DLNG--QVLGVV 178 >4NCX-A nrPDB Length = 506 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 18/38 (47%) Query: 122 IALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTG 159 ++L + LS ++ C+P +P + C+ +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >2WMN-A nrPDB Length = 428 Score = 30.2 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Query: 69 VLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIAL-IKL 127 +LTA HC + + +++ ++ E ++ + ++ + + I L +KL Sbjct: 280 ILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKL 339 Query: 128 AEHVELSDTIQVA 140 V + Sbjct: 340 QGSVSVQVNAGPL 352 >5XIP-A nrPDB Length = 498 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 14/27 (51%) Query: 133 LSDTIQVACLPEKDSLLPKDYPCYVTG 159 ++ ++ C+P +P+ C+ TG Sbjct: 459 MTGAMKPLCIPFDQPPMPEGTRCFFTG 485 >5UBM-B nrPDB Length = 152 Score = 29.8 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 7/19 (36%), Positives = 7/19 (36%) Query: 10 LLACASSCGVPSFPPNLSA 28 L C CGVP P Sbjct: 134 LPKCVPVCGVPREPFEEKQ 152 >5JYK-A nrPDB Length = 566 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 42/121 (34%), Gaps = 26/121 (21%) Query: 40 SWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS 99 S PWQ QY + G +I VLT AH + + +V + K + + Sbjct: 115 SLPWQRKRQYSSGSS------GFIIGGRRVLTNAHSVEHHT--QVKLKKRGSDTKYLATV 166 Query: 100 LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTG 159 L +G + DIAL+ + + E + + E L V G Sbjct: 167 LAIGTEC--------------DIALLTVTDD-EFWEGVSPV---EFGDLPALQDAVTVVG 208 Query: 160 W 160 + Sbjct: 209 Y 209 >4XZB-A nrPDB Length = 314 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%) Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL 177 D+ L P +V+ WG +G L++ Sbjct: 218 DAALQAGTPVFVSEWGTSDASGDGGPYLEEAE 249 >5ILA-A nrPDB Length = 301 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 42/121 (34%), Gaps = 26/121 (21%) Query: 40 SWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS 99 S PWQ QY + G +I VLT AH + + +V + K + + Sbjct: 115 SLPWQRKRQYSSGSS------GFIIGGRRVLTNAHSVEHHT--QVKLKKRGSDTKYLATV 166 Query: 100 LFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTG 159 L +G + DIAL+ + + E + + E L V G Sbjct: 167 LAIGTEC--------------DIALLTVTDD-EFWEGVSPV---EFGDLPALQDAVTVVG 208 Query: 160 W 160 + Sbjct: 209 Y 209 >5XIG-A nrPDB Length = 500 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 17/39 (43%), Gaps = 8/39 (20%) Query: 132 ELSDTIQVACLPEKDSLLPKDYPCYVTG--------WGR 162 ++ ++ C+P +P+ C+ TG WGR Sbjct: 460 VMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGR 498 >2CTL-A nrPDB Length = 97 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 30/85 (35%), Gaps = 10/85 (11%) Query: 87 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALI---KLAEHVELSDTIQVACLP 143 G + E E+ +L ++ V +++ ++ A+I +L V P Sbjct: 1 GSSGSSGEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVN-------IQFP 53 Query: 144 EKDSLLPKDYPCYVTGWGRLWTNGP 168 +KD +TG+ + Sbjct: 54 DKDDGNQPQDQITITGYEKNTEAAR 78 >3AK5-A nrPDB Length = 975 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 11/23 (47%), Gaps = 1/23 (4%) Query: 214 GDSGGPLNCQL-ENGSWEVFGIV 235 GDSG PL W + G++ Sbjct: 205 GDSGSPLFAFDTVQNKWVLVGVL 227 >2JIH-A nrPDB Length = 300 Score = 27.9 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 2/32 (6%) Query: 212 CNGDSGGPLNCQLENGSWEVFGIVSFGSRRGC 243 C G SGG L CQ ++ W G S G + C Sbjct: 259 CTGTSGGVLVCQTKHFPW-ADG-TSCGEGKWC 288 >2PFE-A nrPDB Length = 186 Score = 27.9 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 21/64 (32%), Gaps = 8/64 (12%) Query: 186 CSRIDWWGFRVKKTMVCAGGDGVISAC--NGDSGGPLNCQLENGSWEVFGIVSFGSRRGC 243 C I V+ G +AC GDSGGP + G+ S G C Sbjct: 108 CGTIQSKNQTVRYAEGTVTGLTRTTACAEGGDSGGPWLTGS-----QAQGVTS-GGTGDC 161 Query: 244 NTRK 247 + Sbjct: 162 RSGG 165 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.153 0.562 Lambda K H 0.267 0.0471 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,664,295 Number of Sequences: 36641 Number of extensions: 561055 Number of successful extensions: 2942 Number of sequences better than 10.0: 191 Number of HSP's better than 10.0 without gapping: 334 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 1083 Number of HSP's gapped (non-prelim): 362 length of query: 268 length of database: 10,336,785 effective HSP length: 95 effective length of query: 173 effective length of database: 6,855,890 effective search space: 1186068970 effective search space used: 1186068970 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.1 bits)