BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q99828 (191 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2LM5-A nrPDB 384 e-107 1DGU-A nrPDB 366 e-102 4ORC-B nrPDB 74 5e-14 4IL1-A nrPDB 73 6e-14 5B8I-B nrPDB 71 2e-13 6EPA-A nrPDB 64 3e-11 1UHN-A nrPDB 59 1e-09 2E30-A nrPDB 59 1e-09 2ZFD-A nrPDB 59 1e-09 2LCP-A nrPDB 57 5e-09 2BEC-A nrPDB 54 3e-08 1S1E-A nrPDB 53 6e-08 1S6C-A nrPDB 53 7e-08 1V1G-A nrPDB 52 1e-07 5T7C-A nrPDB 51 2e-07 1BJF-A nrPDB 51 3e-07 5D43-A nrPDB 50 8e-07 5M6C-E nrPDB 49 2e-06 3DD4-A nrPDB 47 4e-06 2JU0-A nrPDB 46 1e-05 2L2E-A nrPDB 45 2e-05 2GGZ-A nrPDB 44 4e-05 3KF9-A nrPDB 44 6e-05 2I94-A nrPDB 43 6e-05 2L1W-A nrPDB 42 2e-04 2N6A-A nrPDB 42 2e-04 2GGM-A nrPDB 42 2e-04 2OBH-A nrPDB 41 3e-04 5YPX-A nrPDB 40 6e-04 3EK4-A nrPDB 40 6e-04 5A2H-A nrPDB 40 7e-04 4OY4-A nrPDB 40 7e-04 3WFN-B nrPDB 40 7e-04 3QRX-A nrPDB 40 8e-04 2F2P-A nrPDB 40 8e-04 6O20-F nrPDB 40 8e-04 3U0K-A nrPDB 40 8e-04 5I0I-E nrPDB 39 0.001 4E53-A nrPDB 39 0.001 2JUL-A nrPDB 39 0.001 2LMV-A nrPDB 39 0.001 6HCS-A nrPDB 39 0.001 2R2I-A nrPDB 39 0.001 4JWQ-A nrPDB 39 0.001 5E37-A nrPDB 39 0.002 2M29-A nrPDB 39 0.002 3HZT-A nrPDB 38 0.003 2RO9-A nrPDB 38 0.003 2B1U-A nrPDB 38 0.003 1FW4-A nrPDB 37 0.004 3LIJ-A nrPDB 37 0.004 4I2Y-A nrPDB 37 0.004 5UKG-A nrPDB 37 0.005 1M39-A nrPDB 37 0.006 3K21-A nrPDB 37 0.006 3L19-A nrPDB 37 0.007 3KHE-A nrPDB 36 0.008 1CLM-A nrPDB 36 0.008 5ZGM-A nrPDB 36 0.009 1RTP-1 nrPDB 36 0.010 3O4Y-A nrPDB 36 0.010 4MVF-A nrPDB 36 0.010 2ROB-A nrPDB 36 0.010 2KN2-A nrPDB 36 0.011 1GGZ-A nrPDB 36 0.012 5MWC-D nrPDB 36 0.012 2M5E-A nrPDB 36 0.013 3PM8-A nrPDB 35 0.014 5H7D-E nrPDB 35 0.015 6IIE-A nrPDB 35 0.016 2NA0-A nrPDB 35 0.017 3Q5I-A nrPDB 35 0.017 2K2I-A nrPDB 35 0.025 5PAL-A nrPDB 35 0.025 2D8N-A nrPDB 35 0.026 5COC-A nrPDB 34 0.030 2KZ2-A nrPDB 34 0.032 2M97-A nrPDB 34 0.034 3IFK-A nrPDB 34 0.045 2I08-A nrPDB 34 0.048 1F55-A nrPDB 33 0.051 5JN2-A nrPDB 33 0.053 3A4U-B nrPDB 33 0.056 2LHH-A nrPDB 33 0.056 2VRG-A nrPDB 33 0.056 2LHI-A nrPDB 33 0.058 1LKJ-A nrPDB 33 0.067 3LCP-C nrPDB 33 0.074 2KQY-A nrPDB 33 0.074 1RK9-A nrPDB 33 0.081 4YGB-B nrPDB 33 0.090 2E6W-A nrPDB 33 0.098 1JBA-A nrPDB 33 0.10 1TOP-A nrPDB 33 0.11 1TRF-A nrPDB 32 0.12 4RGJ-A nrPDB 32 0.12 4Q57-A nrPDB 32 0.13 3PAT-A nrPDB 32 0.13 1TNP-A nrPDB 32 0.13 2KSZ-A nrPDB 32 0.13 1OQP-A nrPDB 32 0.14 2RO8-A nrPDB 32 0.14 5JOJ-A nrPDB 32 0.17 4DS7-A nrPDB 32 0.17 3FWC-A nrPDB 32 0.18 4MSP-A nrPDB 32 0.23 4FL4-C nrPDB 32 0.23 2LAP-A nrPDB 31 0.28 1G33-A nrPDB 31 0.28 2LC5-A nrPDB 31 0.31 4YZB-A nrPDB 31 0.32 1C7W-A nrPDB 31 0.33 2TN4-A nrPDB 31 0.35 4NSC-A nrPDB 31 0.41 1CB1-A nrPDB 30 0.43 2NLN-A nrPDB 30 0.45 1S6J-A nrPDB 30 0.51 2KYF-A nrPDB 30 0.53 5X3F-A nrPDB 30 0.57 2JNF-A nrPDB 30 0.76 3NCG-A nrPDB 30 0.79 1S6I-A nrPDB 30 0.84 2K2A-A nrPDB 30 0.86 5B7X-A nrPDB 30 0.90 5ZOR-A nrPDB 29 0.97 5G5D-B nrPDB 29 1.1 2AMI-A nrPDB 29 1.1 2LV7-A nrPDB 29 1.1 1TTX-A nrPDB 29 1.1 1JC2-A nrPDB 29 1.1 2VCE-A nrPDB 29 1.3 3I46-A nrPDB 29 1.5 3TZ1-A nrPDB 29 1.6 4WOQ-A nrPDB 28 1.8 1ZMZ-A nrPDB 28 2.0 4OKH-A nrPDB 28 2.2 5JOL-A nrPDB 28 2.3 4L9M-A nrPDB 28 2.3 5JVV-B nrPDB 28 2.5 4WPX-A nrPDB 28 2.9 3VLE-A nrPDB 28 3.0 2K7C-A nrPDB 28 3.1 3ROS-A nrPDB 28 3.3 6EAZ-A nrPDB 27 3.9 2BL0-B nrPDB 27 3.9 4I5L-B nrPDB 27 4.1 5OTJ-D nrPDB 27 4.2 2MA2-A nrPDB 27 4.2 4MEW-A nrPDB 27 5.1 1CT9-A nrPDB 27 5.9 5XND-A nrPDB 27 6.2 1F73-A nrPDB 27 7.2 5HYD-A nrPDB 27 7.6 1OHZ-B nrPDB 27 7.7 5VLN-A nrPDB 27 7.9 2Q4U-A nrPDB 26 8.3 2LVK-A nrPDB 26 8.8 >2LM5-A nrPDB Length = 214 Score = 384 bits (987), Expect = e-107, Method: Compositional matrix adjust. Identities = 191/191 (100%), Positives = 191/191 (100%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS Sbjct: 24 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 83 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD Sbjct: 84 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 143 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS Sbjct: 144 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 203 Query: 181 PDFASSFKIVL 191 PDFASSFKIVL Sbjct: 204 PDFASSFKIVL 214 >1DGU-A nrPDB Length = 183 Score = 366 bits (939), Expect = e-102, Method: Compositional matrix adjust. Identities = 183/183 (100%), Positives = 183/183 (100%) Query: 9 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP 68 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP Sbjct: 1 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP 60 Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL Sbjct: 61 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 120 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK Sbjct: 121 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 180 Query: 189 IVL 191 IVL Sbjct: 181 IVL 183 >4ORC-B nrPDB Length = 170 Score = 73.6 bits (179), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 38/123 (30%), Positives = 70/123 (56%), Gaps = 5/123 (4%) Query: 56 EQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIF 115 E+ +SLPEL+ NP +R+ +F T + F++F++ +S FS + K +AFRI+ Sbjct: 41 EEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIY 99 Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D D DG ++ +L +++ + G L ++++Q++D + +D D DG I+ EF Sbjct: 100 DMDKDGYISNGELFQVLKMMVG----NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 155 Query: 176 VIS 178 V+ Sbjct: 156 VVG 158 >4IL1-A nrPDB Length = 823 Score = 73.2 bits (178), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 38/123 (30%), Positives = 70/123 (56%), Gaps = 5/123 (4%) Query: 56 EQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIF 115 E+ +SLPEL+ NP +R+ +F T + F++F++ +S FS + K +AFRI+ Sbjct: 198 EEFMSLPELQQNPLVQRVIDIFDTD-GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIY 256 Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D D DG ++ +L +++ + G L ++++Q++D + +D D DG I+ EF Sbjct: 257 DMDKDGYISNGELFQVLKMMVG----NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCA 312 Query: 176 VIS 178 V+ Sbjct: 313 VVG 315 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 9/97 (9%) Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 ++ F +FL +++ + + AFR+FD D +G ++ +L + +T GE Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV---MTNLGE- 115 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 116 -KLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 147 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 16 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 66 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 67 PEFLTMMAR 75 >5B8I-B nrPDB Length = 171 Score = 71.2 bits (173), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 42/173 (24%), Positives = 89/173 (51%), Gaps = 13/173 (7%) Query: 8 LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKAN 67 +S ++L + + +E+ +RF +L + ++E ++ LSLP++ +N Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIER--------DEFLSLPQVSSN 52 Query: 68 PFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 P R+ +F D + F++F+ LS FS + K +AF+++D D DG ++ + Sbjct: 53 PLSTRMIAIFDEDGGGD-VDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGE 111 Query: 128 LSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 L ++ + G + L +++Q++D + E+D+D DG I+ EF ++ + Sbjct: 112 LFIVLKMMVG----SNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENT 160 >6EPA-A nrPDB Length = 187 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 11/184 (5%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+L ++ + T+ T++EI H+ F + P + + ++ F Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P+ + F + RVF + ++ FE+F+ LS+ S D K H+AFR++D D+D Sbjct: 56 FPDGDPSKFASLVFRVFDEN-NDGAIEFEEFIRALSITS-RGNLDEKLHWAFRLYDVDND 113 Query: 121 GTLNREDLSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 G + RE++ +V+ + G+ T + K+ +D I ++ D + D + L EF+ Sbjct: 114 GYITREEMYNIVDAIYQMVGQQPQTEDENTPQKR-VDKIFDQMDKNHDDRLTLEEFREGS 172 Query: 178 SRSP 181 P Sbjct: 173 KADP 176 >1UHN-A nrPDB Length = 189 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 35/117 (29%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 K + F +R+ +F T L FE+F LSVF A D K H++F+++D G + Sbjct: 51 KESLFADRVFDLFDTK-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIE 109 Query: 125 REDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 R+++ ++V E L + ++ +ID EE+D DG I+ E++ ++ R P Sbjct: 110 RQEVKQMVVATLAES-GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 165 >2E30-A nrPDB Length = 195 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 29/195 (14%) Query: 1 MGGSGSRLSK-ELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL 59 MG S L + E L E + T + +I + RF L E ++ E Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSR--------EDFQ 52 Query: 60 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVF---------SDTATPDI---- 106 +PEL NP +RI F +D ++F F+ L+ F D P+ Sbjct: 53 RIPELAINPLGDRIINAFFPE-GEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSR 111 Query: 107 --KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDR 164 K H+AFR++D D D ++R++L +++ + G +S ++ + D ++E+D D Sbjct: 112 SNKLHFAFRLYDLDKDEKISRDELLQVLRMMVG----VNISDEQLGSIADRTIQEADQDG 167 Query: 165 DGTINLSEFQHVISR 179 D I+ +EF V+ + Sbjct: 168 DSAISFTEFVKVLEK 182 >2ZFD-A nrPDB Length = 226 Score = 58.5 bits (140), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 35/117 (29%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 K + F +R+ +F T L FE+F LSVF A D K H++F+++D G + Sbjct: 82 KESLFADRVFDLFDTK-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIE 140 Query: 125 REDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 R+++ ++V E L + ++ +ID EE+D DG I+ E++ ++ R P Sbjct: 141 RQEVKQMVVATLAES-GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 >2LCP-A nrPDB Length = 190 Score = 57.0 bits (136), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 84/187 (44%), Gaps = 16/187 (8%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S S+L E++ E T+ T++E+ ++ F + P Q F++I Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAG-------FQKIYK 53 Query: 61 --LPELKANPFKERICRVFSTSPAKDS-LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDF 117 P F + VF + KD + F +F+ LSV S T D K +AF+++D Sbjct: 54 QFFPFGDPTKFATFVFNVFDEN--KDGRIEFSEFIQALSVTS-RGTLDEKLRWAFKLYDL 110 Query: 118 DDDGTLNREDLSRLVNCLTGE-GEDTRLSASEM--KQLIDNILEESDIDRDGTINLSEFQ 174 D+DG + R ++ +V+ + G L E ++ +D I D + DG + L EFQ Sbjct: 111 DNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQ 170 Query: 175 HVISRSP 181 P Sbjct: 171 EGSKADP 177 >2BEC-A nrPDB Length = 202 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 39/170 (22%), Positives = 80/170 (47%), Gaps = 29/170 (17%) Query: 20 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 79 T ++ +L H RF R+++ + + + + + L NP +RI F Sbjct: 21 TGFSQASLLRLHHRF--------RALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP 72 Query: 80 SPAKDSLSFEDFLDLLSVF-----SDTATPDIKS-----------HYAFRIFDFDDDGTL 123 ++ + F F+ +L+ F DT T D K HYAF+++D D DG + Sbjct: 73 DGSQ-RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 Query: 124 NREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 +R ++ +++ + G +++ +++ + D ++E+D D DG ++ EF Sbjct: 132 SRHEMLQVLRLMVG----VQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 >1S1E-A nrPDB Length = 224 Score = 53.1 bits (126), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 43/168 (25%), Positives = 78/168 (46%), Gaps = 14/168 (8%) Query: 11 ELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELKANP 68 E L + + T TK+E+ + +R F P S + + F+QI + P A+ Sbjct: 37 EGLEQLEAQTNFTKRELQVLYRGFKNECP-------SGVVNEETFKQIYAQFFPHGDAST 89 Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 + + F T+ S+ FEDF+ LS+ T K + F ++D + DG +N+E++ Sbjct: 90 YAHYLFNAFDTTQT-GSVKFEDFVTALSILL-RGTVHEKLRWTFNLYDINKDGYINKEEM 147 Query: 129 SRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 +V + G+ L +Q +D ++ D ++DG + L EF Sbjct: 148 MDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEF 195 Score = 29.6 bits (65), Expect = 0.84, Method: Compositional matrix adjust. Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + R F ++ E F + + F +HY F FD G++ ED + Sbjct: 56 LYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTAL 115 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 + L R + E + N+ DI++DG IN E ++ D + Sbjct: 116 SILL------RGTVHEKLRWTFNLY---DINKDGYINKEEMMDIVKAIYDMMGKY 161 >1S6C-A nrPDB Length = 183 Score = 53.1 bits (126), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 43/168 (25%), Positives = 78/168 (46%), Gaps = 14/168 (8%) Query: 11 ELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELKANP 68 E L + + T TK+E+ + +R F P S + + F+QI + P A+ Sbjct: 4 EGLEQLEAQTNFTKRELQVLYRGFKNECP-------SGVVNEETFKQIYAQFFPHGDAST 56 Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 + + F T+ S+ FEDF+ LS+ T K + F ++D + DG +N+E++ Sbjct: 57 YAHYLFNAFDTTQT-GSVKFEDFVTALSILL-RGTVHEKLRWTFNLYDINKDGYINKEEM 114 Query: 129 SRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 +V + G+ L +Q +D ++ D ++DG + L EF Sbjct: 115 MDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEF 162 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + R F ++ E F + + F +HY F FD G++ ED + Sbjct: 23 LYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTAL 82 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 + L R + E + N+ DI++DG IN E ++ D + Sbjct: 83 SILL------RGTVHEKLRWTFNLY---DINKDGYINKEEMMDIVKAIYDMMGKY 128 >1V1G-A nrPDB Length = 222 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 + N F +RI VF + F +F+ L VF +A K +AF+++D G + Sbjct: 71 RRNLFADRIFDVFDVK-RNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIE 129 Query: 125 REDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 RE+L +V L E E LS ++ ++D ++D DG I++ E++ +S +P Sbjct: 130 REELKEMVVALLHESE-LVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNP 185 >5T7C-A nrPDB Length = 193 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 22/181 (12%) Query: 2 GGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSL 61 G S+L E+L + ++ T T E+ ++ F + P +V+ + F Sbjct: 2 GKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANF-----F 56 Query: 62 PELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 P A+ F E + R F T+ ++ F +F+ LSV S + K +AF ++D D +G Sbjct: 57 PYGDASKFAEHVFRTFDTN-GDGTIDFREFIIALSVTS-RGKLEQKLKWAFSMYDLDGNG 114 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMK---------QLIDNILEESDIDRDGTINLSE 172 ++R ++ +V + ++ +S MK + D I + D + DG ++L E Sbjct: 115 YISRSEMLEIVQAI------YKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEE 168 Query: 173 F 173 F Sbjct: 169 F 169 >1BJF-A nrPDB Length = 193 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 26/184 (14%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+L E++ + + T T+ EI ++ F P S+E F++I Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEE-------FKKIYG 53 Query: 61 --LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 118 P A+ F E + R F + ++ F +F+ LSV S + K +AF ++D D Sbjct: 54 NFFPYGDASKFAEHVFRTFDAN-GDGTIDFREFIIALSVTS-RGKLEQKLKWAFSMYDLD 111 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMK---------QLIDNILEESDIDRDGTIN 169 +G +++ ++ +V + ++ +S MK + + I + D +RDG ++ Sbjct: 112 GNGYISKAEMLEIVQAIY------KMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLS 165 Query: 170 LSEF 173 L EF Sbjct: 166 LEEF 169 Score = 27.3 bits (59), Expect = 4.1, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 9/92 (9%) Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 LS E+F + F + + FR FD + DGT+ D + L + S Sbjct: 43 LSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTI---DFREFIIAL------SVTS 93 Query: 146 ASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 +++Q + D+D +G I+ +E ++ Sbjct: 94 RGKLEQKLKWAFSMYDLDGNGYISKAEMLEIV 125 >5D43-A nrPDB Length = 178 Score = 49.7 bits (117), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 15/126 (11%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRI 114 +++ L P KE + ++ S A +SF DFL +++ A D K AFR+ Sbjct: 55 VAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT--QKMAEKDTKEEILKAFRL 112 Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD D+ G ++ ++L R+ N L GE L+ E++++ID E+D D DG +N EF Sbjct: 113 FDDDETGKISFKNLKRVANEL-GES----LTDEELQEMID----EADRDGDGEVNEEEFL 163 Query: 175 HVISRS 180 ++ ++ Sbjct: 164 KIMKKT 169 >5M6C-E nrPDB Length = 193 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 86/182 (47%), Gaps = 22/182 (12%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+L E+L + ++ T ++ E+ ++ F + P +V+ + F Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P A+ F E + R F T+ + ++ F +F+ LSV S + K +AF ++D D + Sbjct: 56 FPYGDASKFAEHVFRNFDTN-SDGTIDFREFIIALSVTS-RGRLEQKLMWAFSMYDLDGN 113 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMK---------QLIDNILEESDIDRDGTINLS 171 G ++RE++ +V + ++ +S MK + + I + D + DG ++L Sbjct: 114 GYISREEMLEIVQAI------YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLE 167 Query: 172 EF 173 EF Sbjct: 168 EF 169 >3DD4-A nrPDB Length = 229 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 37/157 (23%), Positives = 74/157 (47%), Gaps = 14/157 (8%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELKANPFKERICRVFST 79 TK+E+ + +R F P S + + F++I S P+ + + + F T Sbjct: 61 FTKKELQILYRGFKNECP-------SGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDT 113 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE---DLSRLVNCLT 136 ++SFEDF+ LS+ T K ++AF ++D + DG + +E D+ + + + Sbjct: 114 D-HNGAVSFEDFIKGLSILL-RGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMM 171 Query: 137 GEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 G+ L +Q ++ ++ D ++DG + + EF Sbjct: 172 GKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEF 208 Score = 27.3 bits (59), Expect = 4.0, Method: Compositional matrix adjust. Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 9/110 (8%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + R F ++ E F ++ S F +H+ F FD D +G ++ ED + + Sbjct: 69 LYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGL 128 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 182 + L R + E N+ DI++DG I E ++ D Sbjct: 129 SIL------LRGTVQEKLNWAFNLY---DINKDGYITKEEMLDIMKAIYD 169 >2JU0-A nrPDB Length = 190 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 46/183 (25%), Positives = 80/183 (43%), Gaps = 22/183 (12%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+LSK+ L + T+ ++EI H+ F P Q + E ++ F Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDT--ATPDIKSHYAFRIFDFD 118 P F + VF KD+ F F + ++V S T T + K +AF ++D + Sbjct: 56 FPFGSPEDFANHLFTVFD----KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLN 111 Query: 119 DDGTLNREDL-------SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 DG + +++ +++ + ED + EM+ + I + D + DG I L Sbjct: 112 HDGYITFDEMLTIVASVYKMMGSMVTLNEDE--ATPEMR--VKKIFKLMDKNEDGYITLD 167 Query: 172 EFQ 174 EF+ Sbjct: 168 EFR 170 >2L2E-A nrPDB Length = 190 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 89/193 (46%), Gaps = 14/193 (7%) Query: 2 GGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS- 60 G S S+LS++ L + T K+E+ ++ F + P S + F++I Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCP-------SGHLNKSEFQKIYKQ 54 Query: 61 -LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 P + F E + VF + F++F+ LSV S D K +AF+++D D+ Sbjct: 55 FFPFGDPSAFAEYVFNVFDAD-KNGYIDFKEFICALSVTSRGELND-KLIWAFQLYDLDN 112 Query: 120 DGTLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHV 176 +G ++ +++ R+V+ + G +L E ++ ++ I D ++DG + L EF Sbjct: 113 NGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEG 172 Query: 177 ISRSPDFASSFKI 189 R P S+ + Sbjct: 173 SKRDPTIVSALSL 185 >2GGZ-A nrPDB Length = 211 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/180 (23%), Positives = 82/180 (45%), Gaps = 28/180 (15%) Query: 25 QEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL--KANPFKERICRVFSTSPA 82 QE + +R F P S L+ F+ +L L L KAN +++ F T+ Sbjct: 19 QETHVWYRTFMMEYP-------SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN-- 69 Query: 83 KDSLSFEDFLDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 KD F DFL+ ++ + + K + F+++D D +G++++ +L + + Sbjct: 70 KDG--FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 127 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH----------VISRSPDFASSFKIV 190 LS E I+ + + DI+ DG + L EF + ++ +S DF++ +++ Sbjct: 128 QQTLSPEE---FINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVI 184 >3KF9-A nrPDB Length = 149 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 33/127 (25%), Positives = 66/127 (51%), Gaps = 11/127 (8%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFD 116 +++ L P KE I ++ + ++ FE+FL +++ + AFR+FD Sbjct: 32 VAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFD 91 Query: 117 FDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 D+ G ++ ++L R+ L GE+ ++ E++++ID E+D D DG +N EF + Sbjct: 92 DDETGKISFKNLKRVAKEL---GEN--MTDEELQEMID----EADRDGDGEVNEEEFFRI 142 Query: 177 ISRSPDF 183 + ++ F Sbjct: 143 MKKTSLF 149 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 13/70 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD--GTI 168 AF +FD D GT++ ++L + L E E+K++I +DID+D GTI Sbjct: 13 AFDLFDTDGSGTIDAKELKVAMRALGFE-----PKKEEIKKMI------ADIDKDGSGTI 61 Query: 169 NLSEFQHVIS 178 + EF +++ Sbjct: 62 DFEEFLQMMT 71 >2I94-A nrPDB Length = 202 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 37/138 (26%), Positives = 69/138 (50%), Gaps = 12/138 (8%) Query: 1 MGGSGS-RLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL 59 MG S S LSKE+L E Q T T++E+ ++ F + P S + F+ I Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECP-------SGRITRQEFQTIY 53 Query: 60 S--LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDF 117 S PE + + + R F + + +L F++++ L + S T + K +AF ++D Sbjct: 54 SKFFPEADPKAYAQHVFRSFDAN-SDGTLDFKEYVIALHMTSAGKT-NQKLEWAFSLYDV 111 Query: 118 DDDGTLNREDLSRLVNCL 135 D +GT+++ ++ +V + Sbjct: 112 DGNGTISKNEVLEIVTAI 129 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 9/90 (10%) Query: 89 EDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASE 148 ++F + S F A P + + FR FD + DGTL D V L SA + Sbjct: 47 QEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTL---DFKEYVIAL------HMTSAGK 97 Query: 149 MKQLIDNILEESDIDRDGTINLSEFQHVIS 178 Q ++ D+D +GTI+ +E +++ Sbjct: 98 TNQKLEWAFSLYDVDGNGTISKNEVLEIVT 127 >2L1W-A nrPDB Length = 149 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 35/114 (30%), Positives = 62/114 (54%), Gaps = 15/114 (13%) Query: 64 LKANPFKERICRVFSTSPA--KDSLSFEDFLDLLS--VFSDTATPDIKSHYAFRIFDFDD 119 L NP +E + + S A ++ F++FL L++ V A ++K AF++FD D Sbjct: 39 LDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMAKKVKDTDAEEELKE--AFKVFDKDQ 96 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 +G ++ S L + + GE +L+ E++Q+I +E+D+D DG +N EF Sbjct: 97 NGYISA---SELRHVMINLGE--KLTDEEVEQMI----KEADLDGDGQVNYEEF 141 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DG + E+L+ ++ L D + E++ +I E D D +GTI Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSL-----DQNPTEEELQDMI----SEVDADGNGTIEF 65 Query: 171 SEFQHVISR 179 EF ++++ Sbjct: 66 DEFLSLMAK 74 >2N6A-A nrPDB Length = 173 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L GE +L Sbjct: 64 TIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---GE--KL 118 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 + E +D ++ E+DID DG +N EF +++ + A S Sbjct: 119 TDEE----VDEMIREADIDGDGQVNYEEFVQMMTGASTAAGS 156 Score = 33.5 bits (75), Expect = 0.054, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ + D D +GTI+ Sbjct: 17 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMINEV----DADGNGTIDF 67 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 68 PEFLTMMAR 76 >2GGM-A nrPDB Length = 172 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 15/126 (11%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRI 114 +++ L P KE I ++ S ++F DFL +++ + D K AF++ Sbjct: 55 VAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMT--QKMSEKDTKEEILKAFKL 112 Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD D+ G ++ ++L R+ L GE+ L+ E++++ID E+D D DG ++ EF Sbjct: 113 FDDDETGKISFKNLKRVAKEL---GEN--LTDEELQEMID----EADRDGDGEVSEQEFL 163 Query: 175 HVISRS 180 ++ ++ Sbjct: 164 RIMKKT 169 Score = 27.3 bits (59), Expect = 4.3, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 13/71 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT--I 168 AF +FD D GT++ ++L + L E E+K++I S+ID++GT + Sbjct: 36 AFDLFDADGTGTIDVKELKVAMRALGFEP-----KKEEIKKMI------SEIDKEGTGKM 84 Query: 169 NLSEFQHVISR 179 N +F V+++ Sbjct: 85 NFGDFLTVMTQ 95 >2OBH-A nrPDB Length = 143 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 15/125 (12%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRI 114 +++ L P KE I ++ S ++F DFL +++ + D K AF++ Sbjct: 30 VAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMT--QKMSEKDTKEEILKAFKL 87 Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD D+ G ++ ++L R+ L GE+ L+ E++++ID E+D D DG ++ EF Sbjct: 88 FDDDETGKISFKNLKRVAKEL---GEN--LTDEELQEMID----EADRDGDGEVSEQEFL 138 Query: 175 HVISR 179 ++ + Sbjct: 139 RIMKK 143 Score = 26.6 bits (57), Expect = 6.8, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 13/72 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT--I 168 AF +FD D GT++ ++L + L E E+K++I S+ID++GT + Sbjct: 11 AFDLFDADGTGTIDVKELKVAMRALGFE-----PKKEEIKKMI------SEIDKEGTGKM 59 Query: 169 NLSEFQHVISRS 180 N +F V+++ Sbjct: 60 NFGDFLTVMTQK 71 >5YPX-A nrPDB Length = 223 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 62/121 (51%), Gaps = 10/121 (8%) Query: 71 ERICRVFSTSPAKDS---LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 +R+ R F KDS +S ++++ LSVF T D K Y F +FD + DG ++RE+ Sbjct: 84 DRVFRAFD----KDSDSYISLTEWVEGLSVFL-RGTLDEKMEYTFTVFDLNGDGYISREE 138 Query: 128 LSRLVN-CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 + +++ CL + + +K L++ L++ D D D ++ +F+ + P + Sbjct: 139 MFQMLKTCLVKQPTEEDPDEG-IKDLVEIALKKMDHDHDSRLSKKDFKDAVLIEPLLLEA 197 Query: 187 F 187 F Sbjct: 198 F 198 >3EK4-A nrPDB Length = 451 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 9/97 (9%) Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L GE Sbjct: 362 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---GE- 417 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 418 -KLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 449 Score = 34.7 bits (78), Expect = 0.027, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 318 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 368 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 369 PEFLTMMAR 377 >5A2H-A nrPDB Length = 149 Score = 40.0 bits (92), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 51/93 (54%), Gaps = 9/93 (9%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 ++ F +FL+L++ + + AFR+FD D +G ++ +L ++ L GE +L Sbjct: 63 TIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNL---GE--KL 117 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + E +D ++ E+D+D DG IN EF V+ Sbjct: 118 TDEE----VDEMIREADVDGDGQINYEEFVKVM 146 Score = 32.0 bits (71), Expect = 0.17, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 11/84 (13%) Query: 98 FSDTATPDIKSHY--AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDN 155 +D T D S + AF +FD D DG + ++L ++ L G++ + +E++ +I+ Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSL---GQNP--TEAELQDMIN- 54 Query: 156 ILEESDIDRDGTINLSEFQHVISR 179 E D D +GTI+ EF ++++R Sbjct: 55 ---EVDADGNGTIDFPEFLNLMAR 75 >4OY4-A nrPDB Length = 415 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 9/94 (9%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L GE +L Sbjct: 70 TIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---GE--KL 124 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + E +D ++ E+DID DG +N EF +++ Sbjct: 125 TDEE----VDEMIREADIDGDGQVNYEEFVQMMT 154 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D DGTI+ Sbjct: 23 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGDGTIDF 73 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 74 PEFLTMMAR 82 >3WFN-B nrPDB Length = 182 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 9/99 (9%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L G Sbjct: 64 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---G 120 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 E +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 121 E--KLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 153 Score = 33.5 bits (75), Expect = 0.064, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ + D D +GTI+ Sbjct: 22 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMINEV----DADGNGTIDF 72 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 73 PEFLTMMAR 81 >3QRX-A nrPDB Length = 169 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 11/127 (8%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFD 116 +++ L P KE I ++ S ++ FE+FL +++ + AFR+FD Sbjct: 52 VAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFD 111 Query: 117 FDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 D+ GT+ +DL R+ L GE+ L+ E++++I E+D + D I+ EF + Sbjct: 112 DDNSGTITIKDLRRVAKEL---GEN--LTEEELQEMI----AEADRNDDNEIDEDEFIRI 162 Query: 177 ISRSPDF 183 + ++ F Sbjct: 163 MKKTSLF 169 Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 13/70 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD--GTI 168 AF +FD D GT++ ++L + L E E+K++I S+ID+D GTI Sbjct: 33 AFDLFDTDGSGTIDAKELKVAMRALGFEP-----KKEEIKKMI------SEIDKDGSGTI 81 Query: 169 NLSEFQHVIS 178 + EF +++ Sbjct: 82 DFEEFLTMMT 91 >2F2P-A nrPDB Length = 179 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 9/94 (9%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L GE +L Sbjct: 63 TIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---GE--KL 117 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + E +D ++ E+DID DG +N EF +++ Sbjct: 118 TDEE----VDEMIREADIDGDGQVNYEEFVQMMT 147 Score = 33.1 bits (74), Expect = 0.070, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 16 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 66 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 67 PEFLTMMAR 75 >6O20-F nrPDB Length = 169 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 11/117 (9%) Query: 64 LKANPFKERICRVFSTSPA--KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 L NP + + + + A ++ F +FL +++ + + AFR+FD D +G Sbjct: 60 LGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 119 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 ++ +L ++ L GE +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 120 YISAAELRHVMTNL---GE--KLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 167 Score = 33.5 bits (75), Expect = 0.059, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 36 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 86 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 87 PEFLTMMAR 95 >3U0K-A nrPDB Length = 442 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D +G ++ +L ++ L GE +L+ E +D ++ E+DID DG +N Sbjct: 382 AFRVFDKDGNGYISAAELRHVMTNL---GE--KLTDEE----VDEMIREADIDGDGQVNY 432 Query: 171 SEFQHVIS 178 EF +++ Sbjct: 433 EEFVQMMT 440 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D DGTI+ Sbjct: 309 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGDGTIDF 359 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 360 PEFLIMMAR 368 >5I0I-E nrPDB Length = 145 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 11/117 (9%) Query: 64 LKANPFKERICRVFSTSPA--KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 L NP + + + + A ++ F +FL +++ + + AFR+FD D +G Sbjct: 38 LGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 97 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 ++ +L ++ L GE +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 98 YISAAELRHVMTNL---GE--KLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 29.6 bits (65), Expect = 0.86, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 40/69 (57%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF + D D DGT+ ++L ++ L G++ + +E++ +I+ + D D +GTI+ Sbjct: 14 AFSLADKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMINEV----DADGNGTIDF 64 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 65 PEFLTMMAR 73 >4E53-A nrPDB Length = 185 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 9/98 (9%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L G Sbjct: 65 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---G 121 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 E +L+ E +D ++ E+DID DG +N EF ++ Sbjct: 122 E--KLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 153 Score = 33.1 bits (74), Expect = 0.070, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ + D D +GTI+ Sbjct: 23 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMINEV----DADGNGTIDF 73 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 74 PEFLTMMAR 82 >2JUL-A nrPDB Length = 256 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 14/191 (7%) Query: 4 SGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--L 61 S R E L + Q T TK+E+ +R F P + L + F+ I S Sbjct: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECP-------TGLVDEDTFKLIYSQFF 122 Query: 62 PELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 P+ A + + F + ++ FEDF+ LS+ T K +AF ++D + DG Sbjct: 123 PQGDATTYAHFLFNAFD-ADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDG 180 Query: 122 TLNREDLSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + +E++ ++ + G L + ++ ++ D ++DG + + EF Sbjct: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 Query: 179 RSPDFASSFKI 189 + + +S ++ Sbjct: 241 KDENIMNSMQL 251 >2LMV-A nrPDB Length = 148 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 11/119 (9%) Query: 64 LKANPFKERICRVFSTSPAKDS--LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 L NP + + + + + ++ L+F +F +++ + + AF+IFD D DG Sbjct: 39 LGQNPTEAELQDLIAEAENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDG 98 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 ++ +L R V GE +++ E ID ++ E+D D DG IN EF +IS+ Sbjct: 99 FISPAEL-RFVMINLGE----KVTDEE----IDEMIREADFDGDGMINYEEFVWMISQK 148 >6HCS-A nrPDB Length = 167 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 58/117 (49%), Gaps = 11/117 (9%) Query: 64 LKANPFKERICRVFSTSPA--KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 L NP + + + + A ++ F +FL +++ + + AFR+FD D +G Sbjct: 40 LGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 99 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 ++ +L + L GE +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 100 YISAAELRHFMTNL---GE--KLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 147 Score = 33.5 bits (75), Expect = 0.060, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ + D D +GTI+ Sbjct: 16 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMINEV----DADGNGTIDF 66 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 67 PEFLTMMAR 75 >2R2I-A nrPDB Length = 198 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/184 (21%), Positives = 81/184 (44%), Gaps = 29/184 (15%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELK--ANPFKERICRVFST 79 L+ E +++F P Q ++ F+Q L L AN + E++ F Sbjct: 11 LSATECHQWYKKFMTECPSGQLTL-------YEFKQFFGLKNLSPSANKYVEQMFETFDF 63 Query: 80 SPAKDSLSFEDFLDLLSVFSDT--ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 + KD + DF++ ++ S D K + F+++D D +G ++R +L ++ + Sbjct: 64 N--KDG--YIDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRA 119 Query: 138 EGE-DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH----------VISRSPDFASS 186 + ++A E ++ ++ DI+ DG ++L EF +++RS D Sbjct: 120 INRCNEAMTAEEFTNMV---FDKIDINGDGELSLEEFMEGVQKDEVLLDILTRSLDLTHI 176 Query: 187 FKIV 190 K++ Sbjct: 177 VKLI 180 >4JWQ-A nrPDB Length = 199 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 37/63 (58%), Gaps = 4/63 (6%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D+DG + +L+ ++ +G T+ +++K++I +E D + DG I+ Sbjct: 133 AFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDVNQVKKMI----QEVDKNNDGKIDF 188 Query: 171 SEF 173 EF Sbjct: 189 YEF 191 >5E37-A nrPDB Length = 356 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 47/87 (54%), Gaps = 9/87 (10%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQ-LIDNILEESDIDRDGTINL 170 F++ D D +G ++RE+L L+ + GE +S + + ++ +E+ D+++DG I+ Sbjct: 35 FKMADVDGNGHIDREELRNLLESME-SGEVYMMSQHWLPEDELERCMEQYDVNKDGVISF 93 Query: 171 SEFQHVISRS-------PDFASSFKIV 190 EF+ +I ++ S+FK V Sbjct: 94 EEFKQIIYDGLLLEGTLAEYESAFKAV 120 >2M29-A nrPDB Length = 171 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 12/97 (12%) Query: 86 LSFEDFLDLLSVFSDTATPDIKS----HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 + FE+F++L+S T + AFR FD D DG + +L + L GE Sbjct: 81 VDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGE--- 137 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 L +E +D +L E D++ DGTI+ EF ++S Sbjct: 138 -PLEGTE----LDEMLREMDLNGDGTIDFDEFVMMLS 169 >3HZT-A nrPDB Length = 467 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDT--RLSASEMKQLIDNILEESDIDRDGTIN 169 FR D + DG L+R++L L DT L +S+++ +D+IL+ D DR+G I Sbjct: 320 FRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRNGYIE 379 Query: 170 LSEF 173 SEF Sbjct: 380 YSEF 383 Score = 30.0 bits (66), Expect = 0.56, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 11/72 (15%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF+ FD D G + E+L RL + E +L+E D + DG ++ Sbjct: 402 AFQQFDSDGSGKITNEELGRLFGVTEVDDETWH-----------QVLQECDKNNDGEVDF 450 Query: 171 SEFQHVISRSPD 182 EF ++ + D Sbjct: 451 EEFVEMMQKICD 462 >2RO9-A nrPDB Length = 69 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 9/67 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D +G ++ + L + +T GE +L+ E +D ++ E+D+D DG IN Sbjct: 9 AFRVFDKDQNGFIS---AAELRHVMTNLGE--KLTDEE----VDEMIREADVDGDGQINY 59 Query: 171 SEFQHVI 177 EF V+ Sbjct: 60 EEFVKVM 66 >2B1U-A nrPDB Length = 71 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 9/71 (12%) Query: 109 HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AFR FD D DG + ++L R + G G+ ++ +D ++ E+D+D+DG + Sbjct: 9 QVAFRAFDQDGDGHITVDELRR---AMAGLGQPL------PQEELDAMIREADVDQDGRV 59 Query: 169 NLSEFQHVISR 179 N EF ++++ Sbjct: 60 NYEEFARMLAQ 70 >1FW4-A nrPDB Length = 71 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D +G ++ +L ++ L GE +L+ E +D ++ E+DID DG +N Sbjct: 11 AFRVFDKDGNGYISAAELRHVMTNL---GE--KLTDEE----VDEMIREADIDGDGQVNY 61 Query: 171 SEFQHVIS 178 EF +++ Sbjct: 62 EEFVQMMT 69 >3LIJ-A nrPDB Length = 494 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D + DG L+R++L + L+GE E +++ +D IL +D DR+G I+ S Sbjct: 352 FRHIDKNGDGQLDRQELIDGYSKLSGE-EVAVFDLPQIESEVDAILGAADFDRNGYIDYS 410 Query: 172 EFQHV 176 EF V Sbjct: 411 EFVTV 415 >4I2Y-A nrPDB Length = 421 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 9/94 (9%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 + F +FL +++ + + + AFR+FD D +G + +L ++ L GE +L Sbjct: 335 TFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDL---GE--KL 389 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + E +D ++ +DID DG +N EF +++ Sbjct: 390 TDEE----VDEMIRVADIDGDGQVNYEEFVQMMT 419 Score = 35.0 bits (79), Expect = 0.021, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D DGT + Sbjct: 288 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGDGTFDF 338 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 339 PEFLTMMAR 347 >5UKG-A nrPDB Length = 419 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 9/94 (9%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 + F +FL +++ + + AFR+FD D +G + +L ++ L GE +L Sbjct: 333 TFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDL---GE--KL 387 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + E +D ++ +DID DG +N EF +++ Sbjct: 388 TDEE----VDEMIRVADIDGDGQVNYEEFVQMMT 417 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D DGT + Sbjct: 286 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGDGTFDF 336 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 337 PEFLTMMAR 345 >1M39-A nrPDB Length = 89 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 55/98 (56%), Gaps = 13/98 (13%) Query: 86 LSFEDFLDLLSVFSDTATPDIKSHY--AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR 143 ++F DFL +++ + D K AF++FD D+ G ++ ++L R+ L GE+ Sbjct: 1 MNFGDFLTVMT--QKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL---GEN-- 53 Query: 144 LSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 L+ E++++ID E+D D DG ++ EF ++ ++ Sbjct: 54 LTDEELQEMID----EADRDGDGEVSEQEFLRIMKKTS 87 >3K21-A nrPDB Length = 191 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 4/68 (5%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D+DG + +L+ ++ +G T+ + +K++I ++ D + DG I+ Sbjct: 127 AFRVFDVDNDGEITTAELAHILYNGNKKGNITQRDVNRVKRMIRDV----DKNNDGKIDF 182 Query: 171 SEFQHVIS 178 EF ++ Sbjct: 183 HEFSEMMK 190 >3L19-A nrPDB Length = 214 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D + DG L+R++L + L+GE E +++ +D IL +D DR+G I+ S Sbjct: 69 FRHIDKNGDGQLDRQELIDGYSKLSGE-EVAVFDLPQIESEVDAILGAADFDRNGYIDYS 127 Query: 172 EFQHV 176 EF V Sbjct: 128 EFVTV 132 >3KHE-A nrPDB Length = 191 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDT--RLSASEMKQLIDNILEESDIDRDGTIN 169 FR D + DG L+R++L L DT L +S+++ +D+IL+ D DR+G I Sbjct: 46 FRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRNGYIE 105 Query: 170 LSEF 173 SEF Sbjct: 106 YSEF 109 Score = 29.6 bits (65), Expect = 0.88, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 11/72 (15%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF+ FD D G + E+L RL T + Q +L+E D + DG ++ Sbjct: 128 AFQQFDSDGSGKITNEELGRLFGV-------TEVDDETWHQ----VLQECDKNNDGEVDF 176 Query: 171 SEFQHVISRSPD 182 EF ++ + D Sbjct: 177 EEFVEMMQKICD 188 >1CLM-A nrPDB Length = 148 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 11/112 (9%) Query: 64 LKANPFKERICRVFSTSPA--KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 L NP + + + + A ++ F +FL L++ + + AF++FD D +G Sbjct: 39 LGQNPTEAELQDMINEVDADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNG 98 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 ++ +L ++ L GE +L+ E +D ++ E+DID DG IN EF Sbjct: 99 LISAAELRHVMTNL---GE--KLTDDE----VDEMIREADIDGDGHINYEEF 141 Score = 33.1 bits (74), Expect = 0.080, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 15 AFALFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 65 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 66 PEFLSLMAR 74 >5ZGM-A nrPDB Length = 110 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 21/115 (18%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHY---------------AFRIFDFDDDGTLNR 125 P L +D +S F D T D K + F I D D G + Sbjct: 2 PMTKVLKADDINKAVSAFKDPGTFDYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEE 61 Query: 126 EDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 E+L ++ + G D LS +E K L L D D DG I EF +++++ Sbjct: 62 EELKSVLKGFSAHGRD--LSDTETKAL----LAAGDSDHDGKIGADEFAKMVAQA 110 >1RTP-1 nrPDB Length = 109 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 9/110 (8%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 E I + A DS + F ++ + +A D+K F I D D G + ++L Sbjct: 9 EDIKKAIGAFTAADSFDHKKFFQMVGLKKKSA-DDVKK--VFHILDKDKSGFIEEDELGS 65 Query: 131 LVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 ++ + + D LSA E K L + D D DG I + EF +++ S Sbjct: 66 ILKGFSSDARD--LSAKETKTL----MAAGDKDGDGKIGVEEFSTLVAES 109 >3O4Y-A nrPDB Length = 196 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D+DG + +L+ ++ G T +++K++I E D + DG I+ Sbjct: 130 AFRVFDVDNDGEITTAELAHVLFNGNKRGNITERDVNQVKKMI----REVDKNGDGKIDF 185 Query: 171 SEFQHVIS 178 EF ++ Sbjct: 186 YEFSEMMK 193 >4MVF-A nrPDB Length = 506 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 22/107 (20%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYA-------FRIFDFDDDGTLNREDLSRLV 132 S A + + DFL AT D +++ F+ FD D +G ++ E+L R+ Sbjct: 407 SNASGQIHYTDFL--------AATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIF 458 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G D + + + ID++L+E D++ DG I+ EF ++S+ Sbjct: 459 ------GRDD-IENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 498 >2ROB-A nrPDB Length = 70 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D +G ++ +L R V GE +L+ E++Q+I +E+D+D DG +N Sbjct: 9 AFKVFDKDQNGYISASEL-RHVMINLGE----KLTDEEVEQMI----KEADLDGDGQVNY 59 Query: 171 SEF 173 EF Sbjct: 60 EEF 62 >2KN2-A nrPDB Length = 92 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D +G ++ +L R V GE +L+ E++Q+I +E+D+D DG +N Sbjct: 14 AFKVFDKDQNGYISASEL-RHVMINLGE----KLTDEEVEQMI----KEADLDGDGQVNY 64 Query: 171 SEF 173 EF Sbjct: 65 EEF 67 >1GGZ-A nrPDB Length = 148 Score = 35.8 bits (81), Expect = 0.012, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ TRL Sbjct: 62 TVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVM---------TRL 112 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + +D ++ +D D DG +N EF V+ Sbjct: 113 GEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 28.1 bits (61), Expect = 2.4, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 13/71 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD--GTI 168 AF +FD D DG + +L ++ L G++ + +E++ ++ S+IDRD GT+ Sbjct: 15 AFSLFDKDGDGCITTRELGTVMRSL---GQNP--TEAELRDMM------SEIDRDGNGTV 63 Query: 169 NLSEFQHVISR 179 + EF +++R Sbjct: 64 DFPEFLGMMAR 74 >5MWC-D nrPDB Length = 311 Score = 35.8 bits (81), Expect = 0.012, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 9/66 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR FD D DG ++RE+ ++ LTGE +L+ + D I +SD D++G I+ Sbjct: 157 FRTFDKDGDGFIDREEFGGIIR-LTGE----QLTDED----PDEIFGDSDTDKNGRIDFD 207 Query: 172 EFQHVI 177 EF ++ Sbjct: 208 EFLKMV 213 >2M5E-A nrPDB Length = 73 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D +G ++ + L + +T GE +L+ E +D ++ E+DID DG IN Sbjct: 13 AFKVFDRDGNGLIS---AAELRHVMTNLGE--KLTDDE----VDEMIREADIDGDGHINY 63 Query: 171 SEF 173 EF Sbjct: 64 EEF 66 >3PM8-A nrPDB Length = 197 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 22/107 (20%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYA-------FRIFDFDDDGTLNREDLSRLV 132 S A + + DFL AT D +++ F+ FD D +G ++ E+L R+ Sbjct: 104 SNASGQIHYTDFL--------AATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIF 155 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G D + + + ID++L+E D++ DG I+ EF ++S+ Sbjct: 156 ------GRDD-IENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 195 >5H7D-E nrPDB Length = 120 Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 61 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 111 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 112 PEFLTMMAR 120 >6IIE-A nrPDB Length = 93 Score = 35.4 bits (80), Expect = 0.016, Method: Compositional matrix adjust. Identities = 15/70 (21%), Positives = 40/70 (57%) Query: 104 PDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 P+ K + F+++D D +G L+ ++ +++ + E SE++ ++ +++E D D Sbjct: 7 PEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYD 66 Query: 164 RDGTINLSEF 173 G+++ +E+ Sbjct: 67 GSGSVSQAEW 76 >2NA0-A nrPDB Length = 205 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 34/164 (20%), Positives = 73/164 (44%), Gaps = 20/164 (12%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELK--ANPFKERICRVFST 79 L+ E +++F P Q ++ F Q L L A+ + E++ F Sbjct: 13 LSSTECHQWYKKFMTECPSGQLTL-------YEFRQFFGLKNLSPWASQYVEQMFETFDF 65 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 + KD + DF++ + S + K + F+++D D +G ++R++L ++ + Sbjct: 66 N--KDG--YIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRA 121 Query: 138 EG--EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 D+ ++A E D + + D++ DG ++L EF + + Sbjct: 122 INPCSDSTMTAEE---FTDTVFSKIDVNGDGELSLEEFMEGVQK 162 >3Q5I-A nrPDB Length = 504 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQL---IDNILEESDIDRDGTI 168 F+ D + DG L++++L N L + + E+K + +DNIL+E D D++G I Sbjct: 361 FKKLDKNGDGQLDKKELIEGYNVL----RNFKNELGELKNVEEEVDNILKEVDFDKNGYI 416 Query: 169 NLSEFQHV 176 SEF V Sbjct: 417 EYSEFISV 424 Score = 30.8 bits (68), Expect = 0.37, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 11/72 (15%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D G + +E+L+ L LT E T +++L E+D ++D I+ Sbjct: 440 AFNLFDTDKSGKITKEELANLFG-LTSISEKT----------WNDVLGEADQNKDNMIDF 488 Query: 171 SEFQHVISRSPD 182 EF ++ + D Sbjct: 489 DEFVSMMHKICD 500 >2K2I-A nrPDB Length = 79 Score = 34.7 bits (78), Expect = 0.025, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 9/71 (12%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D+ G ++ ++L R+ L GE+ L+ E++++ID E+D D DG ++ Sbjct: 16 AFKLFDDDETGKISFKNLKRVAKEL---GEN--LTDEELQEMID----EADRDGDGEVSE 66 Query: 171 SEFQHVISRSP 181 EF ++ ++ Sbjct: 67 QEFLRIMKKTS 77 >5PAL-A nrPDB Length = 109 Score = 34.7 bits (78), Expect = 0.025, Method: Compositional matrix adjust. Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 21/115 (18%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHY---------------AFRIFDFDDDGTLNR 125 P L +D +S F D T D K + F I D D G + Sbjct: 1 PMTKVLKADDINKAISAFKDPGTFDYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEE 60 Query: 126 EDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 E+L ++ + G D L+ +E K L L D D DG I EF +++++ Sbjct: 61 EELKGVLKGFSAHGRD--LNDTETKAL----LAAGDSDHDGKIGADEFAKMVAQA 109 >2D8N-A nrPDB Length = 207 Score = 34.7 bits (78), Expect = 0.026, Method: Compositional matrix adjust. Identities = 29/130 (22%), Positives = 65/130 (50%), Gaps = 11/130 (8%) Query: 8 LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELK 65 LSKE+L E Q T +++E+ ++ F + P + Q F+ I + P+ Sbjct: 16 LSKEILEELQLNTKFSEEELCSWYQSFLKDCP-------TGRITQQQFQSIYAKFFPDTD 68 Query: 66 ANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNR 125 + + + R F ++ +L F++++ L + + T + K +AF ++D D +GT+++ Sbjct: 69 PKAYAQHVFRSFDSN-LDGTLDFKEYVIALHMTTAGKT-NQKLEWAFSLYDVDGNGTISK 126 Query: 126 EDLSRLVNCL 135 ++ +V + Sbjct: 127 NEVLEIVMAI 136 >5COC-A nrPDB Length = 130 Score = 34.3 bits (77), Expect = 0.030, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 68 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 118 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 119 PEFLTMMAR 127 >2KZ2-A nrPDB Length = 94 Score = 34.3 bits (77), Expect = 0.032, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+ D D +G ++ + L + +T GE +L+ E +D ++ E+DID DG +N Sbjct: 34 AFRVEDKDGNGYIS---AAELRHVMTNLGE--KLTDEE----VDEMIREADIDGDGQVNY 84 Query: 171 SEFQHVIS 178 EF +++ Sbjct: 85 EEFVQMMT 92 >2M97-A nrPDB Length = 69 Score = 34.3 bits (77), Expect = 0.034, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 FRIFD D +G ++RE+ ++ LTGE +L+ + +D I +SD D++G I+ Sbjct: 8 CFRIFDKDGNGFIDREEFGDIIR-LTGE----QLTDED----VDEIFGDSDTDKNGRIDF 58 Query: 171 SEF 173 EF Sbjct: 59 DEF 61 >3IFK-A nrPDB Length = 90 Score = 33.9 bits (76), Expect = 0.045, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ + D D +GTI+ Sbjct: 15 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMINEV----DADGNGTIDF 65 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 66 PEFLTMMAR 74 >2I08-A nrPDB Length = 78 Score = 33.9 bits (76), Expect = 0.048, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 39/69 (56%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF ++D D DGT+ ++L ++ L L+ +E + + +++ E D D +GTI+ Sbjct: 15 AFSLYDKDGDGTITTKELGTVMRSL-------GLNPTEAE--LQDMINEVDADGNGTIDF 65 Query: 171 SEFQHVISR 179 EF +++R Sbjct: 66 PEFLTMMAR 74 >1F55-A nrPDB Length = 77 Score = 33.5 bits (75), Expect = 0.051, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D++G+++ +L+ ++ L LS SE + +++++ E D+D + I Sbjct: 15 AFALFDKDNNGSISSSELATVMRSLG-------LSPSEAE--VNDLMNEIDVDGNHQIEF 65 Query: 171 SEFQHVISR 179 SEF ++SR Sbjct: 66 SEFLALMSR 74 >5JN2-A nrPDB Length = 525 Score = 33.5 bits (75), Expect = 0.053, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Query: 112 FRIFDFDDDGTLNREDL-SRLVNCLTGEGED-TRLSASEMKQLIDNILEESDIDRDGTIN 169 F D + DG L+R +L + +G+D + L AS ++ +D +L+ D D++G I Sbjct: 382 FHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIE 441 Query: 170 LSEFQHV 176 SEF V Sbjct: 442 YSEFVTV 448 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 33/67 (49%), Gaps = 11/67 (16%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D+ G ++ +L+ + + E + ++L E D + DG ++ Sbjct: 464 AFRMFDSDNSGKISSTELATIFGVSDVDSETWK-----------SVLSEVDKNNDGEVDF 512 Query: 171 SEFQHVI 177 EFQ ++ Sbjct: 513 DEFQQML 519 >3A4U-B nrPDB Length = 143 Score = 33.5 bits (75), Expect = 0.056, Method: Compositional matrix adjust. Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 4/78 (5%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT---GEGEDTRLSASEMKQLIDN 155 ++ + +++ HY F++ D+D + L+ +LS + + G + +S E+ +ID Sbjct: 62 AEMSPQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 120 Query: 156 ILEESDIDRDGTINLSEF 173 +L + D + DG I+ +EF Sbjct: 121 VLRDDDKNNDGYIDYAEF 138 >2LHH-A nrPDB Length = 128 Score = 33.5 bits (75), Expect = 0.056, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D++G+++ +L+ ++ L LS SE + +++++ E D+D + I Sbjct: 15 AFALFDKDNNGSISSSELATVMRSLG-------LSPSEAE--VNDLMNEIDVDGNHQIEF 65 Query: 171 SEFQHVISR 179 SEF ++SR Sbjct: 66 SEFLALMSR 74 >2VRG-A nrPDB Length = 124 Score = 33.5 bits (75), Expect = 0.056, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT---GEGEDTRLSASEMKQLIDNILEESD 161 +++ HY F++ D+D + L+ +LS + + G + +S E+ +ID +L + D Sbjct: 49 ELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDD 107 Query: 162 IDRDGTINLSEF 173 + DG I+ +EF Sbjct: 108 KNNDGYIDYAEF 119 >2LHI-A nrPDB Length = 176 Score = 33.5 bits (75), Expect = 0.058, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D++G+++ +L+ ++ L LS SE + +++++ E D+D + I Sbjct: 16 AFALFDKDNNGSISSSELATVMRSLG-------LSPSEAE--VNDLMNEIDVDGNHQIEF 66 Query: 171 SEFQHVISR 179 SEF ++SR Sbjct: 67 SEFLALMSR 75 Score = 30.8 bits (68), Expect = 0.42, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 10/96 (10%) Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 + F +FL L+S + + + AF++FD + DG ++ +L + LT GE +L+ Sbjct: 64 IEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELK---HVLTSIGE--KLT 118 Query: 146 ASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 +E +D++L E D G IN+ +F ++S+ Sbjct: 119 DAE----VDDMLREVS-DGSGEINIQQFAALLSKGS 149 >1LKJ-A nrPDB Length = 146 Score = 33.1 bits (74), Expect = 0.067, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D++G+++ +L+ ++ L LS SE + +++++ E D+D + I Sbjct: 15 AFALFDKDNNGSISSSELATVMRSLG-------LSPSEAE--VNDLMNEIDVDGNHQIEF 65 Query: 171 SEFQHVISR 179 SEF ++SR Sbjct: 66 SEFLALMSR 74 Score = 29.6 bits (65), Expect = 0.74, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 15/158 (9%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 LT+++I F S+ SS A V LS E + N I Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEI-----DVD 58 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 + F +FL L+S + + + AF++FD + DG ++ + L + LT GE Sbjct: 59 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISA---AELKHVLTSIGE- 114 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 +L+ +E +D++L E D G IN+ +F ++S+ Sbjct: 115 -KLTDAE----VDDMLREVS-DGSGEINIQQFAALLSK 146 >3LCP-C nrPDB Length = 93 Score = 33.1 bits (74), Expect = 0.074, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT---GEGEDTRLSASEMKQLIDNILEESD 161 +++ HY F++ D+D + L+ +LS + + G + +S E+ +ID +L + D Sbjct: 18 ELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDD 76 Query: 162 IDRDGTINLSEF 173 + DG I+ +EF Sbjct: 77 KNNDGYIDYAEF 88 >2KQY-A nrPDB Length = 108 Score = 33.1 bits (74), Expect = 0.074, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 I S+ A DS +++ F + + S T PD + F I D D G + E+L + Sbjct: 11 IESALSSCQAADSFNYKSFFSTVGLSSKT--PD-QIKKVFGILDQDKSGFIEEEELQLFL 67 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + L+++E K L D D DG I + EFQ ++ Sbjct: 68 KNFSSSAR--VLTSAETKAF----LAAGDTDGDGKIGVEEFQSLV 106 >1RK9-A nrPDB Length = 110 Score = 33.1 bits (74), Expect = 0.081, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 9/110 (8%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 E I + A DS + F ++ + +A D+K F + D D G + ++L Sbjct: 10 EDIKKAVGAFSATDSFDHKKFFQMVGLKKKSA-DDVKK--VFHMLDKDKSGFIEEDELGF 66 Query: 131 LVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 ++ + + D LSA E K L + D D DG I + EF +++ S Sbjct: 67 ILKGFSPDARD--LSAKETKML----MAAGDKDGDGKIGVDEFSTLVAES 110 >4YGB-B nrPDB Length = 104 Score = 32.7 bits (73), Expect = 0.090, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT---GEGEDTRLSASEMKQLIDNILEESD 161 +++ HY F++ D+D + L+ +LS + + G + +S E+ +ID +L + D Sbjct: 29 ELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDD 87 Query: 162 IDRDGTINLSEF 173 + DG I+ +EF Sbjct: 88 KNNDGYIDYAEF 99 >2E6W-A nrPDB Length = 100 Score = 32.7 bits (73), Expect = 0.098, Method: Compositional matrix adjust. Identities = 19/94 (20%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNC---LTGEGEDTRLSASEMKQLIDN 155 S T K +AF ++D + DG + +E++ ++ + G L + ++ Sbjct: 2 SHMGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVER 61 Query: 156 ILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 E+ D ++DG + + EF + + SS ++ Sbjct: 62 FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQL 95 >1JBA-A nrPDB Length = 204 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 28/128 (21%), Positives = 64/128 (50%), Gaps = 11/128 (8%) Query: 55 FEQILSLPE-LKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFR 113 F++ +P+ +A + E + R F T+ +++ F +++ L++ T + K + F+ Sbjct: 45 FKRFFKVPDNEEATQYVEAMFRAFDTN-GDNTIDFLEYVAALNLVL-RGTLEHKLKWTFK 102 Query: 114 IFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQ--------LIDNILEESDIDRD 165 I+D D +G ++R++L +V + + + +Q ++D I D + D Sbjct: 103 IYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGD 162 Query: 166 GTINLSEF 173 G ++L+EF Sbjct: 163 GQLSLNEF 170 >1TOP-A nrPDB Length = 162 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 14/115 (12%) Query: 64 LKANPFKERICRVFST--SPAKDSLSFEDFLDLL-SVFSDTATPDIKSHYA--FRIFDFD 118 L NP KE + + ++ FE+FL ++ + A + A FRIFD + Sbjct: 49 LGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKN 108 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 DG ++ E+L ++ TGE ++ I++++++SD + DG I+ EF Sbjct: 109 ADGFIDIEELGEILRA-TGE--------HVTEEDIEDLMKDSDKNNDGRIDFDEF 154 Score = 30.8 bits (68), Expect = 0.41, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D G ++ ++L ++ L + K+ +D I+EE D D GTI+ Sbjct: 25 AFDMFDADGGGDISTKELGTVMRML---------GQNPTKEELDAIIEEVDEDGSGTIDF 75 Query: 171 SEFQHVISR 179 EF ++ R Sbjct: 76 EEFLVMMVR 84 >1TRF-A nrPDB Length = 76 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D G ++ ++L ++ L + K+ +D I+EE D D GTI+ Sbjct: 14 AFDMFDADGGGDISTKELGTVMRML---------GQNPTKEELDAIIEEVDEDGSGTIDF 64 Query: 171 SEFQHVISR 179 EF ++ R Sbjct: 65 EEFLVMMVR 73 >4RGJ-A nrPDB Length = 520 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Query: 112 FRIFDFDDDGTLNREDLS-RLVNCLTGEGEDTR-LSASEMKQLIDNILEESDIDRDGTIN 169 F+ D + DG L+R +L L +GEDT L + ++ +D IL D+D++G I Sbjct: 377 FKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSIDLDQNGYIE 436 Query: 170 LSEF 173 SEF Sbjct: 437 YSEF 440 Score = 26.6 bits (57), Expect = 6.6, Method: Compositional matrix adjust. Identities = 18/73 (24%), Positives = 38/73 (52%), Gaps = 11/73 (15%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D G ++ +L++L + +S+ K +L+E D + DG I+ Sbjct: 459 AFKLFDKDGSGKISANELAQLFGL-------SDVSSECWK----TVLKEVDQNNDGEIDF 507 Query: 171 SEFQHVISRSPDF 183 EF+ ++ + ++ Sbjct: 508 KEFRDMLVKLCNY 520 >4Q57-A nrPDB Length = 65 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DGT+ ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 7 AFSLFDKDGDGTITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 57 Query: 171 SEFQHVIS 178 EF +++ Sbjct: 58 PEFLTMMA 65 >3PAT-A nrPDB Length = 110 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 13/117 (11%) Query: 64 LKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTL 123 LKA+ K+ + V A+ S + + F L+ + + +A D+K F+ D D G + Sbjct: 7 LKADDIKKALDAV----KAEGSFNHKKFFALVGLKAMSAN-DVKK--VFKAIDADASGFI 59 Query: 124 NREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 E+L ++ +G D L+ +E K L+ +D D DG I + EF+ ++ + Sbjct: 60 EEEELKFVLKSFAADGRD--LTDAETKAF----LKAADKDGDGKIGIDEFETLVHEA 110 >1TNP-A nrPDB Length = 90 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D G ++ ++L ++ L + K+ +D I+EE D D GTI+ Sbjct: 25 AFDMFDADGGGDISTKELGTVMRML---------GQNPTKEELDAIIEEVDEDGSGTIDF 75 Query: 171 SEFQHVISR 179 EF ++ R Sbjct: 76 EEFLVMMVR 84 >2KSZ-A nrPDB Length = 76 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DG + E+L+ ++ L D + E++ +I E D D +GTI Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSL-----DQNPTEEELQDMI----SEVDADGNGTIEF 65 Query: 171 SEFQHVISR 179 EF ++++ Sbjct: 66 DEFLSLMAK 74 >1OQP-A nrPDB Length = 77 Score = 32.3 bits (72), Expect = 0.14, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 42/73 (57%), Gaps = 9/73 (12%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D+ GT+ +DL R+ L GE+ L+ E++++I E+D + D I+ Sbjct: 14 AFRLFDDDNSGTITIKDLRRVAKEL---GEN--LTEEELQEMI----AEADRNDDNEIDE 64 Query: 171 SEFQHVISRSPDF 183 EF ++ ++ F Sbjct: 65 DEFIRIMKKTSLF 77 >2RO8-A nrPDB Length = 79 Score = 32.3 bits (72), Expect = 0.14, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D DG + ++L ++ L G++ + +E++ +I+ E D D +GTI+ Sbjct: 15 AFSLFDKDGDGCITTKELGTVMRSL---GQNP--TEAELQDMIN----EVDADGNGTIDF 65 Query: 171 SEFQHVISR 179 EF ++++R Sbjct: 66 PEFLNLMAR 74 >5JOJ-A nrPDB Length = 97 Score = 32.0 bits (71), Expect = 0.17, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 11/82 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVN--CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AF D D +G ++ +L+ L CL L ++++ +N++ D+D+DG I Sbjct: 17 AFAKVDTDGNGYISFNELNDLFKAACLP-------LPGYRVREITENLMATGDLDQDGRI 69 Query: 169 NLSEFQHVIS--RSPDFASSFK 188 + EF + +S D A +F+ Sbjct: 70 SFDEFIKIFHGLKSTDVAKTFR 91 >4DS7-A nrPDB Length = 147 Score = 32.0 bits (71), Expect = 0.17, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D+ G+++ +L+ ++ L LS SE + + +++ E D+D + I Sbjct: 16 AFALFDKDNSGSISASELATVMRSLG-------LSPSEAE--VADLMNEIDVDGNHAIEF 66 Query: 171 SEFQHVISR 179 SEF ++SR Sbjct: 67 SEFLALMSR 75 Score = 29.6 bits (65), Expect = 0.80, Method: Compositional matrix adjust. Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 10/95 (10%) Query: 85 SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 ++ F +FL L+S + + AF++FD + DG ++ +L + LT GE +L Sbjct: 63 AIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHV---LTSIGE--KL 117 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + +E +D +L E D G IN+ +F ++S+ Sbjct: 118 TDAE----VDEMLREVS-DGSGEINIKQFAALLSK 147 >3FWC-A nrPDB Length = 161 Score = 32.0 bits (71), Expect = 0.18, Method: Compositional matrix adjust. Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 9/70 (12%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D G ++ ++L R+ L GE L+ E++ +I EE D+D DG IN Sbjct: 101 AFQLFDDDHTGKISIKNLRRVAKEL---GE--TLTDEELRAMI----EEFDLDGDGEINE 151 Query: 171 SEFQHVISRS 180 +EF + + S Sbjct: 152 NEFIAICTDS 161 >4MSP-A nrPDB Length = 200 Score = 31.6 bits (70), Expect = 0.23, Method: Compositional matrix adjust. Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 8/95 (8%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 P + +L F +DLL + + +SH +F+ D +DD L+++++ + E Sbjct: 109 PPESTLIFN--IDLLEIRNGP-----RSHESFQEMDLNDDWKLSKDEVKAYLKK-EFEKH 160 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 ++ S L+++I ++ D D+DG I+ EF + Sbjct: 161 GAVVNESHHDALVEDIFDKEDEDKDGFISAREFTY 195 >4FL4-C nrPDB Length = 321 Score = 31.6 bits (70), Expect = 0.23, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 16/93 (17%) Query: 95 LSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 + V DT+ ++ + D D ++N D++ ++ C T+ SA Sbjct: 230 VVVTGDTSVSTSQAPIMMWVGDIVKDNSINLLDVAEVIRCFNA----TKGSA-------- 277 Query: 155 NILEESDIDRDGTINLSEF----QHVISRSPDF 183 N +EE DI+R+G IN+ + +H + S D+ Sbjct: 278 NYVEELDINRNGAINMQDIMIVHKHFGATSSDY 310 >2LAP-A nrPDB Length = 167 Score = 31.2 bits (69), Expect = 0.28, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 12/98 (12%) Query: 86 LSFEDFLDLLSVFSDTATPDIKS----HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 + F+DF++L+ T D+ AFR FD + DG ++ +L + L G Sbjct: 78 VDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVG 137 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 R I+ I+ + D++ DG ++ EF ++SR Sbjct: 138 HRD--------IEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >1G33-A nrPDB Length = 73 Score = 31.2 bits (69), Expect = 0.28, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F I D D G + ++L ++ + + D LSA E K L + D D DG I + Sbjct: 11 FHILDKDKSGFIEEDELGSILKGFSSDARD--LSAKETKTL----MAAGDKDGDGKIGVE 64 Query: 172 EFQHVISRS 180 EF +++ S Sbjct: 65 EFSTLVAES 73 >2LC5-A nrPDB Length = 151 Score = 31.2 bits (69), Expect = 0.31, Method: Compositional matrix adjust. Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 16/86 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTIN- 169 AF++FD D+D L E+L ++ L A+ KQ I I+++ D D G + Sbjct: 19 AFQLFDKDNDNKLTAEELGTVMRA---------LGANPTKQKISEIVKDYDKDNSGKFDQ 69 Query: 170 ------LSEFQHVISRSPDFASSFKI 189 + E+ + + D +F+I Sbjct: 70 ETFLTIMLEYGQEVDSTEDIKKAFEI 95 >4YZB-A nrPDB Length = 491 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Query: 112 FRIFDFDDDGTLNREDLSR-LVNCLTGEGED-TRLSASEMKQLIDNILEESDIDRDGTIN 169 F+ D + DG L++++L V + +GED + L S ++ ++ +L+ D D++G I Sbjct: 345 FQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIE 404 Query: 170 LSEFQHV 176 SEF V Sbjct: 405 YSEFVTV 411 Score = 26.2 bits (56), Expect = 9.3, Method: Compositional matrix adjust. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 11/67 (16%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D G ++ +L+ + + E R +L E D + DG ++ Sbjct: 427 AFGMFDADGSGKISSSELATIFGVSEVDSETWR-----------RVLAEVDRNNDGEVDF 475 Query: 171 SEFQHVI 177 EF+ ++ Sbjct: 476 EEFRQML 482 >1C7W-A nrPDB Length = 81 Score = 30.8 bits (68), Expect = 0.33, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 39/70 (55%), Gaps = 8/70 (11%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD + DG ++ ++ ++ + GE+ A ++ ++E+D D +G I++ Sbjct: 13 AFKVFDANGDGVIDFDEFKFIMQKV---GEEPLTDAE-----VEEAMKEADEDGNGVIDI 64 Query: 171 SEFQHVISRS 180 EF +I +S Sbjct: 65 PEFMDLIKKS 74 >2TN4-A nrPDB Length = 159 Score = 30.8 bits (68), Expect = 0.35, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D G ++ ++L ++ L + K+ +D I+EE D D GTI+ Sbjct: 22 AFDMFDADGGGDISVKELGTVMRML---------GQTPTKEELDAIIEEVDEDGSGTIDF 72 Query: 171 SEFQHVISR 179 EF ++ R Sbjct: 73 EEFLVMMVR 81 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 14/115 (12%) Query: 64 LKANPFKERICRVFST--SPAKDSLSFEDFLDLL-SVFSDTATPDIKSHYA--FRIFDFD 118 L P KE + + ++ FE+FL ++ + A + A FRIFD + Sbjct: 46 LGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRN 105 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 DG ++ E+L+ + +GE ++ E I++++++ D + DG I+ EF Sbjct: 106 ADGYIDAEELAEIFRA-SGE----HVTDEE----IESLMKDGDKNNDGRIDFDEF 151 >4NSC-A nrPDB Length = 401 Score = 30.8 bits (68), Expect = 0.41, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 3/56 (5%) Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F T +SF D++ L +V S TP AF++FD + DG ++ E+ ++ Sbjct: 119 IFYTLGECGLISFSDYIFLTTVLS---TPQRNFEIAFKMFDLNGDGEVDMEEFEQV 171 >1CB1-A nrPDB Length = 78 Score = 30.4 bits (67), Expect = 0.43, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 14/56 (25%) Query: 138 EGEDTRLSASEMKQLI--------------DNILEESDIDRDGTINLSEFQHVISR 179 EG+ +LS E+KQLI D++ +E D + DG ++ EFQ ++ + Sbjct: 20 EGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFEEFQVLVKK 75 >2NLN-A nrPDB Length = 108 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 11/83 (13%) Query: 95 LSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 LS S + DI FR D D G L+ ++L + + + L+ SE K L+D Sbjct: 35 LSKMSASQVKDI-----FRFIDNDQSGYLDGDELKYFLQKFQSDARE--LTESETKSLMD 87 Query: 155 NILEESDIDRDGTINLSEFQHVI 177 +D D DG I EFQ ++ Sbjct: 88 ----AADNDGDGKIGADEFQEMV 106 >1S6J-A nrPDB Length = 87 Score = 30.4 bits (67), Expect = 0.51, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 9/62 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F++ D D+ GT+ ++L + + E L SE+K L+D +DID+ GTI+ Sbjct: 29 FKMIDTDNSGTITFDELKDGLKRVGSE-----LMESEIKDLMDA----ADIDKSGTIDYG 79 Query: 172 EF 173 EF Sbjct: 80 EF 81 >2KYF-A nrPDB Length = 108 Score = 30.4 bits (67), Expect = 0.53, Method: Compositional matrix adjust. Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 9/96 (9%) Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 A DS S + F + S S ++ +K FRI D D G + ++L + E Sbjct: 20 APDSFSPKKFFQI-SGMSKKSSSQLKE--IFRILDNDQSGFIEEDELKYFLQRF--ESGA 74 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 L+ASE K L +D D DG I EFQ ++ Sbjct: 75 RVLTASETK----TFLAAADHDGDGKIGAEEFQEMV 106 >5X3F-A nrPDB Length = 501 Score = 30.0 bits (66), Expect = 0.57, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 35 CELLPQEQRSVESSLRAQVPFEQILSLPEL 64 CEL+ + R +++R QV F +IL LP L Sbjct: 436 CELVIKAARKALAAMRQQVAFYEILHLPNL 465 >2JNF-A nrPDB Length = 158 Score = 29.6 bits (65), Expect = 0.76, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR++D + +G ++ + + ++ L D LS+ ++ +ID I D D GT++ Sbjct: 96 AFRLYDKEGNGYISTDVMREILAEL-----DETLSSEDLDAMIDEI----DADGSGTVDF 146 Query: 171 SEFQHVIS 178 EF V++ Sbjct: 147 EEFMGVMT 154 >3NCG-A nrPDB Length = 486 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 39/63 (61%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D G ++ ++L +L + S+ +M++L ++I+E+ D ++DG ++ Sbjct: 422 AFKMFDKDGSGKISTKELFKLFSQAD--------SSIQMEEL-ESIIEQVDNNKDGEVDF 472 Query: 171 SEF 173 +EF Sbjct: 473 NEF 475 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 17/73 (23%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSA-----------SEMKQLIDNILEES 160 FR D ++DG L+R++L R G E RL S ++ ID+++ Sbjct: 337 FRKLDTNNDGMLDRDELVR------GYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLL 390 Query: 161 DIDRDGTINLSEF 173 D+D G+I SEF Sbjct: 391 DMDGSGSIEYSEF 403 >1S6I-A nrPDB Length = 188 Score = 29.6 bits (65), Expect = 0.84, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 9/62 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F++ D D+ GT+ ++L + + E L SE+K L+D +DID+ GTI+ Sbjct: 16 FKMIDTDNSGTITFDELKDGLKRVGSE-----LMESEIKDLMD----AADIDKSGTIDYG 66 Query: 172 EF 173 EF Sbjct: 67 EF 68 >2K2A-A nrPDB Length = 70 Score = 29.6 bits (65), Expect = 0.86, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR++D + +G ++ + + ++ L D LS+ ++ +ID I D D GT++ Sbjct: 8 AFRLYDKEGNGYISTDVMREILAEL-----DETLSSEDLDAMIDEI----DADGSGTVDF 58 Query: 171 SEFQHVIS 178 EF V++ Sbjct: 59 EEFMGVMT 66 >5B7X-A nrPDB Length = 156 Score = 29.6 bits (65), Expect = 0.90, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 7/63 (11%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQL--IDNILEES 160 T +IK AF +FD D DG + DL+ + LT G+ +++ E++++ I I ES Sbjct: 83 TREIKLRKAFEVFDQDKDGKIKASDLA---HNLTTVGD--KMTKEEVEKVFSILGITMES 137 Query: 161 DID 163 DID Sbjct: 138 DID 140 >5ZOR-A nrPDB Length = 149 Score = 29.3 bits (64), Expect = 0.97, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 13/69 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGE--GEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AF++FD D G ++ +L + L GE G+D ++ ++ E+D D DG + Sbjct: 86 AFQLFDLDKKGKISFANLKEVAKLL-GENPGDD----------VLQEMIAEADEDGDGEV 134 Query: 169 NLSEFQHVI 177 + EF+ V+ Sbjct: 135 SFEEFKSVM 143 >5G5D-B nrPDB Length = 164 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 16/68 (23%) Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF----QH 175 D ++N D++ ++ C T+ SA N +EE DI+R+G IN+ + +H Sbjct: 106 DNSINLLDVAEVIRCFNA----TKGSA--------NYVEELDINRNGAINMQDIMIVHKH 153 Query: 176 VISRSPDF 183 + S D+ Sbjct: 154 FGATSSDY 161 >2AMI-A nrPDB Length = 96 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF +FD D GT++ ++L + L E + K+ I ++ E D D GTI+ Sbjct: 35 AFDLFDTDGSGTIDAKELKVAMRALGFEPK---------KEEIKKMISEIDKDGSGTIDF 85 Query: 171 SEF 173 EF Sbjct: 86 EEF 88 >2LV7-A nrPDB Length = 100 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD D +G +++++L + L + L I++ D+D DG ++ Sbjct: 41 AFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEV---------IIQRLDMDGDGQVDF 91 Query: 171 SEF 173 EF Sbjct: 92 EEF 94 >1TTX-A nrPDB Length = 109 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D D G L+ E+L + E L+ SE K L + +D D DG I Sbjct: 48 FRFIDNDQSGYLDEEELKFFLQKF--ESGARELTESETKSL----MAAADNDGDGKIGAE 101 Query: 172 EFQHVI 177 EFQ ++ Sbjct: 102 EFQEMV 107 >1JC2-A nrPDB Length = 76 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 9/62 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FRIFD + DG ++ E+L ++ TGE +++ I++++++SD + DG I+ Sbjct: 16 FRIFDKNADGFIDIEELGEILRA-TGE--------HVIEEDIEDLMKDSDKNNDGRIDFD 66 Query: 172 EF 173 EF Sbjct: 67 EF 68 >2VCE-A nrPDB Length = 480 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 24/34 (70%), Gaps = 1/34 (2%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQL 152 DDG + RE+++R+V L EGE+ + ++MK+L Sbjct: 410 DDGLVRREEVARVVKGLM-EGEEGKGVRNKMKEL 442 >3I46-A nrPDB Length = 317 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 20/121 (16%) Query: 68 PFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 P KE+I VF + D+ S + F V++ H GT + + Sbjct: 129 PIKEKIQHVFKSGCGFDNDSNKGF-----VYTKIEKNGKNVHVI---------GTHTQSE 174 Query: 128 LSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 SR C G G D ++ A +MK++ D +++ +I +D T+ + +V +P+F Sbjct: 175 DSR---C--GAGHDRKIRAEQMKEISD-FVKKKNIPKDETVYIGGDLNVNKGTPEFKDML 228 Query: 188 K 188 K Sbjct: 229 K 229 >3TZ1-A nrPDB Length = 74 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 9/70 (12%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+ D + G + + L ++ L E L+ E I+N++ E+D D GT++ Sbjct: 12 AFRVLDKEKKGVIKVDVLRWILKSLGDE-----LTEDE----IENMIAETDTDGSGTVDY 62 Query: 171 SEFQHVISRS 180 EF+ ++ S Sbjct: 63 EEFKCLMMSS 72 >4WOQ-A nrPDB Length = 302 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 17/90 (18%) Query: 100 DTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV----------NCLTG--EGEDTRLSAS 147 D T D+K Y+ + FD +G +N + L +++ G GE+ LS Sbjct: 9 DMRTTDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGSTGENFMLSTD 68 Query: 148 EMKQLI----DNILEESD-IDRDGTINLSE 172 E K++ D + EE I + G++NL E Sbjct: 69 EKKRIFEIAKDEVKEEIKLIAQVGSVNLKE 98 >1ZMZ-A nrPDB Length = 98 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 13/71 (18%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT--I 168 AF +FD D GT++ ++L + L E + E+K++I S+ID++GT + Sbjct: 36 AFDLFDADGTGTIDVKELKVAMRALGFEPK-----KEEIKKMI------SEIDKEGTGKM 84 Query: 169 NLSEFQHVISR 179 N +F V+++ Sbjct: 85 NFGDFLTVMTQ 95 >4OKH-A nrPDB Length = 189 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/70 (21%), Positives = 30/70 (42%), Gaps = 20/70 (28%) Query: 139 GEDTRLSASEMKQLIDNILEES--------------------DIDRDGTINLSEFQHVIS 178 G+D + A E+K++++ ++ + D D G +NL EF H+ + Sbjct: 23 GDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWN 82 Query: 179 RSPDFASSFK 188 + + FK Sbjct: 83 KIKAWQKIFK 92 >5JOL-A nrPDB Length = 82 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 9/68 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVN--CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AF D D +G ++ +L+ L CL L ++++ +N++ D+D+DG I Sbjct: 17 AFAKVDTDGNGYISFNELNDLFKAACLP-------LPGYRVREITENLMATGDLDQDGRI 69 Query: 169 NLSEFQHV 176 + EF + Sbjct: 70 SFDEFIKI 77 >4L9M-A nrPDB Length = 559 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 10/41 (24%), Positives = 25/41 (60%) Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 D + + +++++D++ + D D+DG I+ EF+ + + P Sbjct: 415 DPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 >5JVV-B nrPDB Length = 298 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 18/31 (58%) Query: 83 KDSLSFEDFLDLLSVFSDTATPDIKSHYAFR 113 KDSLS +DFLD S F+D + HY R Sbjct: 6 KDSLSGKDFLDAFSFFADRDPTNGFVHYVSR 36 >4WPX-A nrPDB Length = 177 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR+FD D G + +DL ++ + D + A ++EE D + G ++ Sbjct: 116 AFRLFDVDGKGMITEDDLRKVCQQVGNNIPDADIQA---------MIEEFDSNGKGGVDE 166 Query: 171 SEF 173 EF Sbjct: 167 DEF 169 >3VLE-A nrPDB Length = 500 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 11/38 (28%), Positives = 24/38 (63%) Query: 58 ILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLL 95 ++SLP++ P I R +++ + DSL+++ LD++ Sbjct: 63 VVSLPDMDVKPLLATIKRFLTSNVSYDSLNYDYLLDVV 100 >2K7C-A nrPDB Length = 72 Score = 27.7 bits (60), Expect = 3.1, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 8/69 (11%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR FD + DG ++ +L + L G R I+ I+ + D++ DG ++ Sbjct: 12 AFREFDTNGDGEISTSELREAMRKLLGHQVGHRD--------IEEIIRDVDLNGDGRVDF 63 Query: 171 SEFQHVISR 179 EF ++SR Sbjct: 64 EEFVRMMSR 72 >3ROS-A nrPDB Length = 484 Score = 27.7 bits (60), Expect = 3.3, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 13/82 (15%) Query: 16 YQDLTFLTK-QEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERI- 73 Y D T + I++ R+ E+L E ++V S+L+A P E +LP + + KE++ Sbjct: 259 YNDGQVCTSSKRIIVEKSRYDEVL-HELKNVFSNLKAGDPLEADTTLPPMNSEKAKEKLE 317 Query: 74 ----------CRVFSTSPAKDS 85 +VF P DS Sbjct: 318 AQVKEAIDAGAKVFYQYPEIDS 339 >6EAZ-A nrPDB Length = 379 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 13/54 (24%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Query: 83 KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 K +S+ ++L LL++ + P H AF++ D D + + R++ +L ++ Sbjct: 99 KGVISYTEYLFLLTILTK---PHSGFHVAFKMLDVDGNEMIERKEFVKLQKIIS 149 >2BL0-B nrPDB Length = 145 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 9/63 (14%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AFR D + +GT+ +L +L+ L L++SE+++L ++E + DG IN Sbjct: 81 AFRALDKEGNGTIQEAELRQLLLNL-----GDALTSSEVEEL----MKEVSVSGDGAINY 131 Query: 171 SEF 173 F Sbjct: 132 ESF 134 >4I5L-B nrPDB Length = 413 Score = 27.3 bits (59), Expect = 4.1, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 +S+ DF+ L D TP Y FR D D DG L+ +L Sbjct: 253 ISYADFVWFLISEEDKKTP-TSIEYWFRCMDLDGDGALSMFEL 294 >5OTJ-D nrPDB Length = 110 Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 14/81 (17%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ FD + DG ++ LS L + L G SA E++++ + E D D DG I+ + Sbjct: 9 FKRFDTNGDGKIS---LSELTDALRTLGS---TSADEVQRM----MAEIDTDGDGFIDFN 58 Query: 172 EFQHVISRSP----DFASSFK 188 EF + +P D A FK Sbjct: 59 EFISFCNANPGLMKDVAKVFK 79 >2MA2-A nrPDB Length = 81 Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 D L ++++++++ D+D DG I+ EFQ + P + S+F Sbjct: 3 DQALVVEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFP-YLSAF 48 >4MEW-A nrPDB Length = 356 Score = 26.9 bits (58), Expect = 5.1, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 8/61 (13%) Query: 75 RVFSTSPAKD-------SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 R+FS + + +S+ DF+ L D TP Y FR D D DG L+ + Sbjct: 227 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTP-TSIEYWFRCMDLDGDGALSMFE 285 Query: 128 L 128 L Sbjct: 286 L 286 >1CT9-A nrPDB Length = 553 Score = 26.9 bits (58), Expect = 5.9, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS-ASEMKQLI 153 D++ +AF ++D + D L D ++ G E +L ASEMK L+ Sbjct: 116 DLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALV 165 >5XND-A nrPDB Length = 114 Score = 26.6 bits (57), Expect = 6.2, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 10/80 (12%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSR-LVNCLTGEGEDTRLSASEMKQLIDNIL 157 S +T ++K AF I D D G + E+L L N G LS +E K L Sbjct: 42 SGKSTDEVKK--AFAIIDQDKSGFIEEEELKLFLQNFKAGA---RALSDAETKAF----L 92 Query: 158 EESDIDRDGTINLSEFQHVI 177 + D D DG I + EF +I Sbjct: 93 KAGDSDGDGKIGIDEFAAMI 112 >1F73-A nrPDB Length = 293 Score = 26.6 bits (57), Expect = 7.2, Method: Compositional matrix adjust. Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 17/85 (20%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLV----------NCLTG--EGEDTRLSASEMKQL 152 D+K ++ + F++DGT+N + L +++ G GE+ LS E K++ Sbjct: 3 DLKGIFSALLVSFNEDGTINEKGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTEEKKEI 62 Query: 153 IDNILEESD-----IDRDGTINLSE 172 +E+ I + G++NL E Sbjct: 63 FRIAKDEAKDQIALIAQVGSVNLKE 87 >5HYD-A nrPDB Length = 99 Score = 26.6 bits (57), Expect = 7.6, Method: Compositional matrix adjust. Identities = 10/35 (28%), Positives = 23/35 (65%) Query: 144 LSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 LS + QL+D I+++ D ++D ++ +EF +++ Sbjct: 46 LSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVA 80 >1OHZ-B nrPDB Length = 60 Score = 26.6 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 11/57 (19%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSE 172 D + DGT+N DL+ L + S L D+ +D+D++G+IN ++ Sbjct: 3 DVNGDGTINSTDLTML-----------KRSVLRAITLTDDAKARADVDKNGSINSTD 48 >5VLN-A nrPDB Length = 120 Score = 26.6 bits (57), Expect = 7.9, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 41/71 (57%), Gaps = 10/71 (14%) Query: 111 AFRIFDFD-DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTIN 169 AF IF +DG+++ ++L +++ L G++ + E++++ID + D D GT++ Sbjct: 23 AFDIFVLGAEDGSISTKELGKVMRML---GQNP--TPEELQEMIDEV----DEDGSGTVD 73 Query: 170 LSEFQHVISRS 180 EF ++ RS Sbjct: 74 FDEFLVMMVRS 84 >2Q4U-A nrPDB Length = 272 Score = 26.2 bits (56), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/78 (17%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 +R +D D G ++ +L + L + + ++ +++ + D +++ D ++DG ++L+ Sbjct: 110 WRKYDADSSGYISAAELKNFLKDLFLQHK-KKIPPNKLDEYTDAMMKIFDKNKDGRLDLN 168 Query: 172 EFQHVISRSPDFASSFKI 189 + +++ +F FK+ Sbjct: 169 DLARILALQENFLLQFKM 186 >2LVK-A nrPDB Length = 77 Score = 26.2 bits (56), Expect = 8.8, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 10/70 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ FD + DG ++ LS L + L G SA E++++ + E D D DG I+ + Sbjct: 8 FKRFDTNGDGKIS---LSELTDALRTLGS---TSADEVQRM----MAEIDTDGDGFIDFN 57 Query: 172 EFQHVISRSP 181 EF + +P Sbjct: 58 EFISFCNANP 67 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2LM5-A nrPDB 208 9e-55 1DGU-A nrPDB 191 2e-49 5T7C-A nrPDB 190 3e-49 2LCP-A nrPDB 188 1e-48 1BJF-A nrPDB 187 2e-48 2JUL-A nrPDB 184 2e-47 5M6C-E nrPDB 184 2e-47 2L2E-A nrPDB 183 4e-47 6EPA-A nrPDB 181 2e-46 2JU0-A nrPDB 174 1e-44 1S6C-A nrPDB 172 9e-44 1S1E-A nrPDB 171 1e-43 3DD4-A nrPDB 169 5e-43 4IL1-A nrPDB 146 5e-36 5B8I-B nrPDB 142 6e-35 4ORC-B nrPDB 135 1e-32 2R2I-A nrPDB 135 1e-32 2I94-A nrPDB 133 5e-32 2E30-A nrPDB 131 2e-31 2ZFD-A nrPDB 130 5e-31 1V1G-A nrPDB 129 9e-31 3EK4-A nrPDB 126 5e-30 3U0K-A nrPDB 126 7e-30 4OY4-A nrPDB 126 7e-30 2BEC-A nrPDB 125 1e-29 1UHN-A nrPDB 125 1e-29 2GGZ-A nrPDB 122 8e-29 2N6A-A nrPDB 115 8e-27 3WFN-B nrPDB 114 2e-26 6O20-F nrPDB 110 3e-25 2F2P-A nrPDB 110 4e-25 4E53-A nrPDB 107 2e-24 5I0I-E nrPDB 107 4e-24 6HCS-A nrPDB 106 5e-24 5YPX-A nrPDB 105 2e-23 5A2H-A nrPDB 102 1e-22 2L1W-A nrPDB 97 3e-21 2LMV-A nrPDB 94 3e-20 3QRX-A nrPDB 94 4e-20 3KF9-A nrPDB 92 2e-19 2GGM-A nrPDB 90 6e-19 5D43-A nrPDB 90 7e-19 2OBH-A nrPDB 83 6e-17 2M29-A nrPDB 79 1e-15 4JWQ-A nrPDB 77 4e-15 5E37-A nrPDB 74 4e-14 Sequences not found previously or not previously below threshold: 2D8N-A nrPDB 128 1e-30 2NA0-A nrPDB 125 1e-29 5UKG-A nrPDB 117 3e-27 4I2Y-A nrPDB 116 5e-27 1JBA-A nrPDB 113 4e-26 1CLM-A nrPDB 100 3e-22 1GGZ-A nrPDB 97 3e-21 2E6W-A nrPDB 97 4e-21 2LHI-A nrPDB 78 2e-15 3O4Y-A nrPDB 76 1e-14 1LKJ-A nrPDB 73 6e-14 4DS7-A nrPDB 72 1e-13 1DTL-A nrPDB 72 1e-13 3K21-A nrPDB 72 1e-13 5JN2-A nrPDB 72 1e-13 1TOP-A nrPDB 72 2e-13 2HF5-A nrPDB 72 2e-13 2LAP-A nrPDB 72 2e-13 2TN4-A nrPDB 71 2e-13 4YZB-A nrPDB 71 5e-13 1FW4-A nrPDB 70 5e-13 3FWC-A nrPDB 70 5e-13 4RGJ-A nrPDB 70 6e-13 1M39-A nrPDB 70 7e-13 4MVF-A nrPDB 69 1e-12 2KZ2-A nrPDB 69 2e-12 2KN2-A nrPDB 69 2e-12 3PM8-A nrPDB 66 1e-11 2M5E-A nrPDB 66 1e-11 2RO9-A nrPDB 65 2e-11 5ZOR-A nrPDB 65 2e-11 3HZT-A nrPDB 65 2e-11 3NCG-A nrPDB 65 2e-11 2LHH-A nrPDB 65 2e-11 2ROB-A nrPDB 64 4e-11 2JNF-A nrPDB 64 5e-11 1S6I-A nrPDB 62 2e-10 5MWC-D nrPDB 61 4e-10 2LV7-A nrPDB 60 5e-10 2AAO-A nrPDB 60 6e-10 3LIJ-A nrPDB 60 7e-10 6IIE-A nrPDB 60 8e-10 3KHE-A nrPDB 59 2e-09 2K2I-A nrPDB 59 2e-09 3Q5I-A nrPDB 59 2e-09 2B1U-A nrPDB 58 2e-09 1OQP-A nrPDB 57 5e-09 3L19-A nrPDB 56 1e-08 2K7C-A nrPDB 55 1e-08 5COC-A nrPDB 54 4e-08 5JOJ-A nrPDB 54 6e-08 5H7D-E nrPDB 53 8e-08 5JOL-A nrPDB 53 8e-08 2LC5-A nrPDB 52 1e-07 2AMI-A nrPDB 52 1e-07 2Q4U-A nrPDB 52 1e-07 3IFK-A nrPDB 52 2e-07 3J04-B nrPDB 52 2e-07 2JNX-A nrPDB 51 4e-07 2K2A-A nrPDB 50 4e-07 1YX7-A nrPDB 50 4e-07 2BL0-C nrPDB 50 4e-07 1JFJ-A nrPDB 50 6e-07 1JC2-A nrPDB 50 6e-07 2I08-A nrPDB 50 7e-07 4WPX-A nrPDB 50 7e-07 5PAL-A nrPDB 50 7e-07 4Q57-A nrPDB 49 9e-07 2RO8-A nrPDB 49 9e-07 2KSZ-A nrPDB 49 1e-06 1GGW-A nrPDB 49 1e-06 1SR6-C nrPDB 49 1e-06 5ZGM-A nrPDB 48 2e-06 2G9B-A nrPDB 48 2e-06 2M97-A nrPDB 48 3e-06 5OTJ-D nrPDB 47 3e-06 3PAT-A nrPDB 47 4e-06 1OZS-A nrPDB 47 4e-06 2BL0-B nrPDB 47 5e-06 5E1J-A nrPDB 47 5e-06 3AAJ-A nrPDB 47 5e-06 4ZCV-A nrPDB 47 6e-06 4N5X-A nrPDB 47 6e-06 1C7W-A nrPDB 47 6e-06 1W7I-B nrPDB 46 8e-06 2M8U-A nrPDB 46 8e-06 3JAX-C nrPDB 46 8e-06 2LVK-A nrPDB 45 2e-05 3E3R-A nrPDB 45 2e-05 3LCP-C nrPDB 45 2e-05 2VRG-A nrPDB 45 2e-05 1ZMZ-A nrPDB 45 2e-05 5XND-A nrPDB 45 2e-05 5TBY-C nrPDB 45 2e-05 3A4U-B nrPDB 45 2e-05 6FSA-D nrPDB 45 2e-05 4YGB-B nrPDB 45 3e-05 2NCO-A nrPDB 44 4e-05 2OPO-A nrPDB 44 5e-05 1TRF-A nrPDB 44 6e-05 1H4B-A nrPDB 44 6e-05 1F55-A nrPDB 44 6e-05 1TNP-A nrPDB 43 6e-05 2SAS-A nrPDB 43 7e-05 2KYF-A nrPDB 43 7e-05 5H53-C nrPDB 43 7e-05 2N7L-C nrPDB 43 7e-05 2K7B-A nrPDB 43 8e-05 5VLN-A nrPDB 43 8e-05 3I5H-B nrPDB 43 1e-04 1I84-U nrPDB 43 1e-04 1O1A-B nrPDB 42 1e-04 1Y1X-A nrPDB 42 1e-04 1RTP-1 nrPDB 42 2e-04 4I5L-B nrPDB 42 2e-04 4P5W-A nrPDB 42 2e-04 5TBY-E nrPDB 42 2e-04 2KQY-A nrPDB 42 2e-04 5ZH6-A nrPDB 41 3e-04 3DTP-E nrPDB 41 3e-04 5Z1Q-A nrPDB 41 4e-04 4MEW-A nrPDB 41 4e-04 3AKA-A nrPDB 41 4e-04 1N2D-A nrPDB 40 4e-04 1RK9-A nrPDB 40 4e-04 4GJF-A nrPDB 40 6e-04 3TZ1-A nrPDB 40 7e-04 2JOJ-A nrPDB 40 8e-04 6EAZ-A nrPDB 39 0.001 2W4G-C nrPDB 39 0.001 3MSE-B nrPDB 39 0.001 1A75-A nrPDB 39 0.001 5B7X-A nrPDB 39 0.002 4P5X-A nrPDB 39 0.002 3JBH-C nrPDB 39 0.002 2NLN-A nrPDB 39 0.002 5CPV-A nrPDB 38 0.002 5VE9-A nrPDB 38 0.002 5XOP-A nrPDB 38 0.002 1QX2-A nrPDB 38 0.002 4MSP-A nrPDB 38 0.002 1JUO-A nrPDB 38 0.003 3I5I-C nrPDB 38 0.003 5I2L-A nrPDB 38 0.003 2M1U-A nrPDB 37 0.004 1TTX-A nrPDB 37 0.004 4L9M-A nrPDB 37 0.004 4PAL-A nrPDB 37 0.004 2HPS-A nrPDB 37 0.004 1BU3-A nrPDB 37 0.004 2I18-A nrPDB 37 0.004 4NSC-A nrPDB 37 0.004 1JF0-A nrPDB 37 0.005 2OS8-B nrPDB 37 0.005 2MA2-A nrPDB 37 0.005 5MRA-A nrPDB 37 0.005 2L50-A nrPDB 37 0.005 1S6J-A nrPDB 37 0.005 1CB1-A nrPDB 37 0.007 3KPX-A nrPDB 36 0.008 6AGI-A nrPDB 36 0.009 1S36-A nrPDB 36 0.009 1TIZ-A nrPDB 36 0.010 4NQG-A nrPDB 36 0.011 1ZFS-A nrPDB 36 0.011 2PMY-A nrPDB 35 0.013 2EC6-B nrPDB 35 0.014 6AGH-A nrPDB 35 0.014 3CS1-A nrPDB 35 0.016 1G33-A nrPDB 35 0.016 4I5K-A nrPDB 35 0.018 4OCI-A nrPDB 35 0.020 1QLS-A nrPDB 35 0.022 5H53-B nrPDB 35 0.023 1B7T-Y nrPDB 35 0.023 5VT9-A nrPDB 35 0.027 3TS5-B nrPDB 35 0.028 2FCE-A nrPDB 34 0.030 3A8R-A nrPDB 34 0.031 1SL8-A nrPDB 34 0.032 4D1E-A nrPDB 34 0.033 5MKE-A nrPDB 34 0.039 1DFK-Y nrPDB 34 0.041 1KQV-A nrPDB 34 0.043 2LUC-A nrPDB 34 0.044 1BOD-A nrPDB 34 0.051 2N8Y-A nrPDB 34 0.057 1GJY-A nrPDB 34 0.061 3H4S-E nrPDB 34 0.062 1SJJ-A nrPDB 34 0.063 6DU8-A nrPDB 33 0.067 6MI5-X nrPDB 33 0.068 1NSH-A nrPDB 33 0.074 2M7M-A nrPDB 33 0.076 2WCE-A nrPDB 33 0.078 2MBX-A nrPDB 33 0.078 5W1A-B nrPDB 33 0.081 6D1W-A nrPDB 33 0.086 1Q80-A nrPDB 33 0.096 2L0P-A nrPDB 32 0.11 3RNC-B nrPDB 32 0.11 1IJ5-A nrPDB 32 0.12 1QXP-A nrPDB 32 0.12 2AUC-A nrPDB 32 0.13 4AOM-A nrPDB 32 0.14 2LVV-A nrPDB 32 0.14 1UHK-A nrPDB 32 0.17 2YY5-A nrPDB 32 0.20 6DS2-B nrPDB 32 0.24 4OKH-A nrPDB 31 0.25 5HLO-A nrPDB 31 0.28 3SIA-A nrPDB 31 0.28 2KGR-A nrPDB 31 0.33 3DF0-A nrPDB 31 0.37 5HYD-A nrPDB 31 0.37 1F4Q-A nrPDB 31 0.39 1NYA-A nrPDB 30 0.44 5CSF-A nrPDB 30 0.47 4HRG-A nrPDB 30 0.50 1DJX-A nrPDB 30 0.52 4C0K-A nrPDB 30 0.62 4FTG-A nrPDB 30 0.65 5I2U-A nrPDB 30 0.68 2JXC-A nrPDB 30 0.71 2MJW-B nrPDB 30 0.76 1NUB-A nrPDB 30 0.76 4YBH-B nrPDB 29 0.92 2MHH-A nrPDB 29 1.1 3I5J-B nrPDB 29 1.1 2JQ6-A nrPDB 29 1.1 2Y3N-B nrPDB 29 1.3 4U3S-B nrPDB 29 1.4 2KFH-A nrPDB 29 1.4 5KU1-A nrPDB 29 1.5 1KFU-L nrPDB 29 1.6 4XZE-A nrPDB 29 1.7 2Y5I-A nrPDB 29 1.7 5X2E-A nrPDB 29 1.7 5COV-A nrPDB 28 2.3 1SNL-A nrPDB 28 2.4 4WI0-B nrPDB 28 2.4 3BSH-A nrPDB 27 3.5 2KLD-A nrPDB 27 3.7 4PCW-A nrPDB 27 3.8 5NRM-B nrPDB 27 4.2 1SRA-A nrPDB 27 4.4 5VP3-A nrPDB 27 5.2 1KFX-S nrPDB 27 5.6 3BOW-B nrPDB 27 6.1 2JTT-A nrPDB 27 6.1 2KQ6-A nrPDB 27 7.0 1WY9-A nrPDB 27 7.0 5NRK-B nrPDB 27 7.3 5MVF-A nrPDB 27 7.3 5LXV-B nrPDB 26 8.0 1NP8-A nrPDB 26 8.6 1K1D-A nrPDB 26 9.4 1FI6-A nrPDB 26 9.5 >2LM5-A nrPDB Length = 214 Score = 208 bits (530), Expect = 9e-55, Method: Composition-based stats. Identities = 191/191 (100%), Positives = 191/191 (100%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS Sbjct: 24 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 83 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD Sbjct: 84 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 143 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS Sbjct: 144 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 203 Query: 181 PDFASSFKIVL 191 PDFASSFKIVL Sbjct: 204 PDFASSFKIVL 214 >1DGU-A nrPDB Length = 183 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 183/183 (100%), Positives = 183/183 (100%) Query: 9 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP 68 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP Sbjct: 1 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANP 60 Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL Sbjct: 61 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 120 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK Sbjct: 121 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 180 Query: 189 IVL 191 IVL Sbjct: 181 IVL 183 >5T7C-A nrPDB Length = 193 Score = 190 bits (483), Expect = 3e-49, Method: Composition-based stats. Identities = 43/190 (22%), Positives = 82/190 (43%), Gaps = 10/190 (5%) Query: 2 GGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSL 61 G S+L E+L + ++ T T E+ ++ F + P +V+ + F Sbjct: 2 GKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANF-----F 56 Query: 62 PELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 P A+ F E + R F T+ ++ F +F+ LSV S + K +AF ++D D +G Sbjct: 57 PYGDASKFAEHVFRTFDTN-GDGTIDFREFIIALSVTS-RGKLEQKLKWAFSMYDLDGNG 114 Query: 122 TLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVIS 178 ++R ++ +V + ++ E ++ D I + D + DG ++L EF Sbjct: 115 YISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAK 174 Query: 179 RSPDFASSFK 188 P + Sbjct: 175 SDPSIVRLLQ 184 >2LCP-A nrPDB Length = 190 Score = 188 bits (477), Expect = 1e-48, Method: Composition-based stats. Identities = 48/192 (25%), Positives = 82/192 (42%), Gaps = 10/192 (5%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S S+L E++ E T+ T++E+ ++ F + P Q + F Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P F + VF + + F +F+ LSV S T D K +AF+++D D+D Sbjct: 56 FPFGDPTKFATFVFNVFDEN-KDGRIEFSEFIQALSVTS-RGTLDEKLRWAFKLYDLDND 113 Query: 121 GTLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVI 177 G + R ++ +V+ + G L E ++ +D I D + DG + L EFQ Sbjct: 114 GYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGS 173 Query: 178 SRSPDFASSFKI 189 P + + Sbjct: 174 KADPSIVQALSL 185 >1BJF-A nrPDB Length = 193 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 43/191 (22%), Positives = 82/191 (42%), Gaps = 10/191 (5%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+L E++ + + T T+ EI ++ F P S+E + F Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P A+ F E + R F + ++ F +F+ LSV S + K +AF ++D D + Sbjct: 56 FPYGDASKFAEHVFRTFDAN-GDGTIDFREFIIALSVTS-RGKLEQKLKWAFSMYDLDGN 113 Query: 121 GTLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVI 177 G +++ ++ +V + ++ E ++ + I + D +RDG ++L EF Sbjct: 114 GYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGA 173 Query: 178 SRSPDFASSFK 188 P + Sbjct: 174 KSDPSIVRLLQ 184 >2JUL-A nrPDB Length = 256 Score = 184 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 38/189 (20%), Positives = 76/189 (40%), Gaps = 10/189 (5%) Query: 4 SGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPE 63 S R E L + Q T TK+E+ +R F P ++ F P+ Sbjct: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQF-----FPQ 124 Query: 64 LKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTL 123 A + + F ++ FEDF+ LS+ T K +AF ++D + DG + Sbjct: 125 GDATTYAHFLFNAFDA-DGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCI 182 Query: 124 NREDLSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +E++ ++ + G L + ++ ++ D ++DG + + EF + Sbjct: 183 TKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 Query: 181 PDFASSFKI 189 + +S ++ Sbjct: 243 ENIMNSMQL 251 >5M6C-E nrPDB Length = 193 Score = 184 bits (467), Expect = 2e-47, Method: Composition-based stats. Identities = 43/191 (22%), Positives = 86/191 (45%), Gaps = 10/191 (5%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+L E+L + ++ T ++ E+ ++ F + P +V+ + F Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P A+ F E + R F T+ + ++ F +F+ LSV S + K +AF ++D D + Sbjct: 56 FPYGDASKFAEHVFRNFDTN-SDGTIDFREFIIALSVTS-RGRLEQKLMWAFSMYDLDGN 113 Query: 121 GTLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVI 177 G ++RE++ +V + ++ E ++ + I + D + DG ++L EF Sbjct: 114 GYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGA 173 Query: 178 SRSPDFASSFK 188 P + Sbjct: 174 KSDPSIVRLLQ 184 >2L2E-A nrPDB Length = 190 Score = 183 bits (464), Expect = 4e-47, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 86/191 (45%), Gaps = 10/191 (5%) Query: 2 GGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSL 61 G S S+LS++ L + T K+E+ ++ F + P + + F Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQF-----F 56 Query: 62 PELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 P + F E + VF + F++F+ LSV S + K +AF+++D D++G Sbjct: 57 PFGDPSAFAEYVFNVFDA-DKNGYIDFKEFICALSVTS-RGELNDKLIWAFQLYDLDNNG 114 Query: 122 TLNREDLSRLVNCLTGE-GEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVIS 178 ++ +++ R+V+ + G +L E ++ ++ I D ++DG + L EF Sbjct: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSK 174 Query: 179 RSPDFASSFKI 189 R P S+ + Sbjct: 175 RDPTIVSALSL 185 >6EPA-A nrPDB Length = 187 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 9/191 (4%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+L ++ + T+ T++EI H+ F + P + + ++ F Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P+ + F + RVF + ++ FE+F+ LS+ S D K H+AFR++D D+D Sbjct: 56 FPDGDPSKFASLVFRVFDEN-NDGAIEFEEFIRALSITS-RGNLDEKLHWAFRLYDVDND 113 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVIS 178 G + RE++ +V+ + + E ++ +D I ++ D + D + L EF+ Sbjct: 114 GYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSK 173 Query: 179 RSPDFASSFKI 189 P + + Sbjct: 174 ADPRMVQALSL 184 >2JU0-A nrPDB Length = 190 Score = 174 bits (442), Expect = 1e-44, Method: Composition-based stats. Identities = 46/192 (23%), Positives = 80/192 (41%), Gaps = 10/192 (5%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 MG S+LSK+ L + T+ ++EI H+ F P Q + E ++ F Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQF----- 55 Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 P F + VF + FE+F+ +LS S T + K +AF ++D + D Sbjct: 56 FPFGSPEDFANHLFTVFD-KDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHD 113 Query: 121 GTLNREDLSRLVNCLTG-EGEDTRLSASE--MKQLIDNILEESDIDRDGTINLSEFQHVI 177 G + +++ +V + G L+ E + + I + D + DG I L EF+ Sbjct: 114 GYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173 Query: 178 SRSPDFASSFKI 189 P + + Sbjct: 174 KVDPSIIGALNL 185 >1S6C-A nrPDB Length = 183 Score = 172 bits (435), Expect = 9e-44, Method: Composition-based stats. Identities = 42/185 (22%), Positives = 79/185 (42%), Gaps = 10/185 (5%) Query: 8 LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKAN 67 E L + + T TK+E+ + +R F P + E+ + F P A+ Sbjct: 1 HRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQF-----FPHGDAS 55 Query: 68 PFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 + + F T+ S+ FEDF+ LS+ T K + F ++D + DG +N+E+ Sbjct: 56 TYAHYLFNAFDTTQ-TGSVKFEDFVTALSILL-RGTVHEKLRWTFNLYDINKDGYINKEE 113 Query: 128 LSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFA 184 + +V + G+ L +Q +D ++ D ++DG + L EF + Sbjct: 114 MMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIM 173 Query: 185 SSFKI 189 S ++ Sbjct: 174 RSLQL 178 >1S1E-A nrPDB Length = 224 Score = 171 bits (434), Expect = 1e-43, Method: Composition-based stats. Identities = 42/185 (22%), Positives = 79/185 (42%), Gaps = 10/185 (5%) Query: 8 LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKAN 67 E L + + T TK+E+ + +R F P + E+ + F P A+ Sbjct: 34 HRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQF-----FPHGDAS 88 Query: 68 PFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 + + F T+ S+ FEDF+ LS+ T K + F ++D + DG +N+E+ Sbjct: 89 TYAHYLFNAFDTTQ-TGSVKFEDFVTALSILL-RGTVHEKLRWTFNLYDINKDGYINKEE 146 Query: 128 LSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFA 184 + +V + G+ L +Q +D ++ D ++DG + L EF + Sbjct: 147 MMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIM 206 Query: 185 SSFKI 189 S ++ Sbjct: 207 RSLQL 211 >3DD4-A nrPDB Length = 229 Score = 169 bits (429), Expect = 5e-43, Method: Composition-based stats. Identities = 38/188 (20%), Positives = 80/188 (42%), Gaps = 10/188 (5%) Query: 5 GSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL 64 R E L + + TK+E+ + +R F P + E+ F P+ Sbjct: 44 TVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQF-----FPQG 98 Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 + + + F T ++SFEDF+ LS+ T K ++AF ++D + DG + Sbjct: 99 DSTTYAHFLFNAFDT-DHNGAVSFEDFIKGLSILL-RGTVQEKLNWAFNLYDINKDGYIT 156 Query: 125 REDLSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 +E++ ++ + G+ L +Q ++ ++ D ++DG + + EF + Sbjct: 157 KEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDE 216 Query: 182 DFASSFKI 189 + S ++ Sbjct: 217 NIMRSMQL 224 >4IL1-A nrPDB Length = 823 Score = 146 bits (369), Expect = 5e-36, Method: Composition-based stats. Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 13/162 (8%) Query: 16 YQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICR 75 + + EI +RF +L S+ E+ +SLPEL+ NP +R+ Sbjct: 166 LEMCSHFDADEIKRLGKRFKKLDLDNSGSL--------SVEEFMSLPELQQNPLVQRVID 217 Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 +F T + F++F++ +S FS + K +AFRI+D D DG ++ +L +++ + Sbjct: 218 IFDT-DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 276 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 G L ++++Q++D + +D D DG I+ EF V+ Sbjct: 277 VG----NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 Score = 127 bits (319), Expect = 3e-30, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 69/161 (42%), Gaps = 18/161 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 57 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 58 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 113 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 114 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK 149 >5B8I-B nrPDB Length = 171 Score = 142 bits (359), Expect = 6e-35, Method: Composition-based stats. Identities = 41/173 (23%), Positives = 87/173 (50%), Gaps = 13/173 (7%) Query: 8 LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKAN 67 +S ++L + + +E+ +RF +L + ++E ++ LSLP++ +N Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIER--------DEFLSLPQVSSN 52 Query: 68 PFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 P R+ +F + F++F+ LS FS + K +AF+++D D DG ++ + Sbjct: 53 PLSTRMIAIFDEDGG-GDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGE 111 Query: 128 LSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 L ++ + G L +++Q++D + E+D+D DG I+ EF ++ + Sbjct: 112 LFIVLKMMVGS----NLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENT 160 >4ORC-B nrPDB Length = 170 Score = 135 bits (339), Expect = 1e-32, Method: Composition-based stats. Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 13/162 (8%) Query: 16 YQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICR 75 + + EI +RF +L S+ E+ +SLPEL+ NP +R+ Sbjct: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSL--------SVEEFMSLPELQQNPLVQRVID 60 Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 +F T + F++F++ +S FS + K +AFRI+D D DG ++ +L +++ + Sbjct: 61 IFDT-DGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM 119 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 G L ++++Q++D + +D D DG I+ EF V+ Sbjct: 120 VG----NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 31/81 (38%), Gaps = 13/81 (16%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 A + F+ D D+ G+L+ E+ L + L+ +++ Sbjct: 14 HFDADEIKRLGKRFKKLDLDNSGSLSVEEFM-------------SLPELQQNPLVQRVID 60 Query: 159 ESDIDRDGTINLSEFQHVISR 179 D D +G ++ EF +S+ Sbjct: 61 IFDTDGNGEVDFKEFIEGVSQ 81 >2R2I-A nrPDB Length = 198 Score = 135 bits (339), Expect = 1e-32, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 74/176 (42%), Gaps = 15/176 (8%) Query: 15 EYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKA--NPFKER 72 + + + L+ E +++F P Q ++ F+Q L L N + E+ Sbjct: 4 DSKAVEELSATECHQWYKKFMTECPSGQLTL-------YEFKQFFGLKNLSPSANKYVEQ 56 Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + F + + F +++ LS+ D K + F+++D D +G ++R +L ++ Sbjct: 57 MFETFDFN-KDGYIDFMEYVAALSLVLK-GKVDQKLRWYFKLYDVDGNGCIDRGELLNII 114 Query: 133 NCLTGEGE-DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 + + ++A E ++ ++ DI+ DG ++L EF + + Sbjct: 115 KAIRAINRCNEAMTAEEFTNMV---FDKIDINGDGELSLEEFMEGVQKDEVLLDIL 167 >2I94-A nrPDB Length = 202 Score = 133 bits (334), Expect = 5e-32, Method: Composition-based stats. Identities = 37/194 (19%), Positives = 78/194 (40%), Gaps = 13/194 (6%) Query: 1 MGGSGS-RLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL 59 MG S S LSKE+L E Q T T++E+ ++ F + P + + + F Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKF---- 56 Query: 60 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 PE + + + R F + + +L F++++ L + S + K +AF ++D D Sbjct: 57 -FPEADPKAYAQHVFRSFDAN-SDGTLDFKEYVIALHMTSA-GKTNQKLEWAFSLYDVDG 113 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLS-----ASEMKQLIDNILEESDIDRDGTINLSEFQ 174 +GT+++ ++ +V + + ++ + I D + EF Sbjct: 114 NGTISKNEVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFI 173 Query: 175 HVISRSPDFASSFK 188 + + + Sbjct: 174 EGTLANKEILRLIQ 187 >2E30-A nrPDB Length = 195 Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats. Identities = 48/195 (24%), Positives = 85/195 (43%), Gaps = 29/195 (14%) Query: 1 MGGSGSRLSK-ELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL 59 MG S L + E L E + T + +I + RF L E ++ E Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSR--------EDFQ 52 Query: 60 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDI------------- 106 +PEL NP +RI F +D ++F F+ L+ F + Sbjct: 53 RIPELAINPLGDRIINAFFP-EGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSR 111 Query: 107 --KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDR 164 K H+AFR++D D D ++R++L +++ + G +S ++ + D ++E+D D Sbjct: 112 SNKLHFAFRLYDLDKDEKISRDELLQVLRMMVG----VNISDEQLGSIADRTIQEADQDG 167 Query: 165 DGTINLSEFQHVISR 179 D I+ +EF V+ + Sbjct: 168 DSAISFTEFVKVLEK 182 >2ZFD-A nrPDB Length = 226 Score = 130 bits (326), Expect = 5e-31, Method: Composition-based stats. Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 5/174 (2%) Query: 16 YQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICR 75 T + EI + F ++ ++ L + F+ L K + F +R+ Sbjct: 36 LARDTVFSVSEIEALYELFKKI---SSAVIDDGLINKEEFQLALFKTNKKESLFADRVFD 92 Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 +F T L FE+F LSVF A D K H++F+++D G + R+++ ++V Sbjct: 93 LFDTK-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 E L + ++ +ID EE+D DG I+ E++ ++ R P + + Sbjct: 152 LAES-GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 >1V1G-A nrPDB Length = 222 Score = 129 bits (323), Expect = 9e-31, Method: Composition-based stats. Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 8/190 (4%) Query: 3 GSGSRLSKELLAE---YQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL 59 + + + +T T +E+ + F +L ++ L + F+ L Sbjct: 9 KKKNAMRPPGYEDPELLASVTPFTVEEVEALYELFKKL---SSSIIDDGLIHKEEFQLAL 65 Query: 60 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 + N F +RI VF + F +F+ L VF +A K +AF+++D Sbjct: 66 FRNRNRRNLFADRIFDVFDVK-RNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQ 124 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G + RE+L +V L E E LS ++ ++D ++D DG I++ E++ +S Sbjct: 125 TGFIEREELKEMVVALLHESE-LVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSL 183 Query: 180 SPDFASSFKI 189 +P + + Sbjct: 184 NPSLIKNMTL 193 >2D8N-A nrPDB Length = 207 Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 76/187 (40%), Gaps = 12/187 (6%) Query: 7 RLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKA 66 LSKE+L E Q T +++E+ ++ F + P + + + F P+ Sbjct: 15 ALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKF-----FPDTDP 69 Query: 67 NPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE 126 + + + R F ++ +L F++++ L + + K +AF ++D D +GT+++ Sbjct: 70 KAYAQHVFRSFDSNL-DGTLDFKEYVIALHMT-TAGKTNQKLEWAFSLYDVDGNGTISKN 127 Query: 127 DLSRLVNCLTGEGEDTRLS-----ASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 ++ +V + + + ++ + I + + D + EF + Sbjct: 128 EVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK 187 Query: 182 DFASSFK 188 + + Sbjct: 188 EILRLIQ 194 >3EK4-A nrPDB Length = 451 Score = 126 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 34/168 (20%), Positives = 71/168 (42%), Gaps = 18/168 (10%) Query: 15 EYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERIC 74 EY LT+++I F ++ + V + L NP + + Sbjct: 300 EYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQ 352 Query: 75 RVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + + + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ Sbjct: 353 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM 412 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 L +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 413 TNL-----GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK 451 Score = 59.7 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 16/103 (15%) Query: 85 SLSFEDFLDLLSVFSDTATPDI-------KSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 + F++ ++L + T D + AF +FD D DGT+ ++L ++ L Sbjct: 285 GIDFKEDGNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL-- 342 Query: 138 EGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 + +E++ +I+ E D D +GTI+ EF +++R Sbjct: 343 ---GQNPTEAELQDMIN----EVDADGNGTIDFPEFLTMMARK 378 >3U0K-A nrPDB Length = 442 Score = 126 bits (316), Expect = 7e-30, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 69/161 (42%), Gaps = 18/161 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 298 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 350 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 351 ADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 406 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 407 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK 442 >4OY4-A nrPDB Length = 415 Score = 126 bits (316), Expect = 7e-30, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 70/163 (42%), Gaps = 18/163 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 64 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 65 ADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 120 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 182 +L+ E +D ++ E+DID DG +N EF +++ + Sbjct: 121 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAKLE 158 >2BEC-A nrPDB Length = 202 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 32/197 (16%) Query: 1 MGGSGS--RLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQI 58 MG S + + + T ++ +L H RF R+++ + + + + Sbjct: 1 MGSRSSHAAVIPDG-DSIRRETGFSQASLLRLHHRF--------RALDRNKKGYLSRMDL 51 Query: 59 LSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDI------------ 106 + L NP +RI F ++ + F F+ +L+ F D Sbjct: 52 QQIGALAVNPLGDRIIESFFPDGSQ-RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLN 110 Query: 107 ----KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDI 162 K HYAF+++D D DG ++R ++ +++ + G +++ +++ + D ++E+D Sbjct: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG----VQVTEEQLENIADRTVQEADE 166 Query: 163 DRDGTINLSEFQHVISR 179 D DG ++ EF + + Sbjct: 167 DGDGAVSFVEFTKSLEK 183 >1UHN-A nrPDB Length = 189 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 5/174 (2%) Query: 16 YQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICR 75 T + EI + F ++ ++ L + F+ L K + F +R+ Sbjct: 5 LARDTVFSVSEIEALYELFKKI---SSAVIDDGLINKEEFQLALFKTNKKESLFADRVFD 61 Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 +F T L FE+F LSVF A D K H++F+++D G + R+++ ++V Sbjct: 62 LFDTK-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 120 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 E L + ++ +ID EE+D DG I+ E++ ++ R P + + Sbjct: 121 LAES-GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >2NA0-A nrPDB Length = 205 Score = 125 bits (313), Expect = 1e-29, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 69/169 (40%), Gaps = 12/169 (7%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKA--NPFKERICRVFS 78 L+ E +++F P Q ++ F Q L L + + E++ F Sbjct: 12 ELSSTECHQWYKKFMTECPSGQLTL-------YEFRQFFGLKNLSPWASQYVEQMFETFD 64 Query: 79 TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 + + F ++ LS+ + K + F+++D D +G ++R++L ++ + Sbjct: 65 FN-KDGYIDFMEYEAALSLVLK-GKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAI 122 Query: 139 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 + S ++ D + + D++ DG ++L EF + + + Sbjct: 123 NPCSD-STMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTL 170 >2GGZ-A nrPDB Length = 211 Score = 122 bits (307), Expect = 8e-29, Method: Composition-based stats. Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 14/165 (8%) Query: 25 QEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL--KANPFKERICRVFSTSPA 82 QE + +R F P S L+ F+ +L L L KAN +++ F T+ Sbjct: 19 QETHVWYRTFMMEYP-------SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN-K 70 Query: 83 KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDT 142 + F +F+ +++ + K + F+++D D +G++++ +L + + Sbjct: 71 DGFVDFLEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 129 Query: 143 RLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 LS E I+ + + DI+ DG + L EF + +++ D Sbjct: 130 TLSPEE---FINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 171 >5UKG-A nrPDB Length = 419 Score = 117 bits (293), Expect = 3e-27, Method: Composition-based stats. Identities = 33/175 (18%), Positives = 70/175 (40%), Gaps = 18/175 (10%) Query: 8 LSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKAN 67 + K+ L LT+++I F ++ + V + L N Sbjct: 261 MQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQN 313 Query: 68 PFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNR 125 P + + + + + + F +FL +++ + + AFR+FD D +G + Sbjct: 314 PTEAELQDMINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGA 373 Query: 126 EDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L ++ L +L+ E +D ++ +DID DG +N EF +++ Sbjct: 374 AELRHVMTDL-----GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQMMTAK 419 Score = 57.8 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 9/77 (11%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D DG Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGDG 332 Query: 167 TINLSEFQHVISRSPDF 183 T + EF +++R + Sbjct: 333 TFDFPEFLTMMARKMSY 349 >4I2Y-A nrPDB Length = 421 Score = 116 bits (291), Expect = 5e-27, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 67/161 (41%), Gaps = 18/161 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 277 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 329 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + + F +FL +++ + + + AFR+FD D +G + +L ++ L Sbjct: 330 ADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDL---- 385 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L+ E +D ++ +DID DG +N EF +++ Sbjct: 386 -GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQMMTAK 421 Score = 27.8 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 1/45 (2%) Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + E +L+ ++ + D D DGTI E V+ Sbjct: 266 KTMGWEATRDQLTEEQIAEF-KEAFSLFDKDGDGTITTKELGTVM 309 >2N6A-A nrPDB Length = 173 Score = 115 bits (289), Expect = 8e-27, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 71/166 (42%), Gaps = 18/166 (10%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST--S 80 T+++I F ++ + V + L NP + + + + + Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVDA 59 Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 60 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL----- 114 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 +L+ E +D ++ E+DID DG +N EF +++ + A S Sbjct: 115 GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTGASTAAGS 156 >3WFN-B nrPDB Length = 182 Score = 114 bits (285), Expect = 2e-26, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 69/161 (42%), Gaps = 18/161 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 11 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 63 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 64 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 119 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 120 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK 155 >1JBA-A nrPDB Length = 204 Score = 113 bits (283), Expect = 4e-26, Method: Composition-based stats. Identities = 32/178 (17%), Positives = 77/178 (43%), Gaps = 18/178 (10%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELK-ANPFKERICRVFSTSP 81 ++ +++F E P + F++ +P+ + A + E + R F T+ Sbjct: 20 DAAQLQEWYKKFLEECPSGTLFM-------HEFKRFFKVPDNEEATQYVEAMFRAFDTN- 71 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 +++ F +++ L++ T + K + F+I+D D +G ++R++L +V + + Sbjct: 72 GDNTIDFLEYVAALNLVL-RGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKA 130 Query: 142 TRLSASE--------MKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKIVL 191 + ++++D I D + DG ++L+EF R ++ L Sbjct: 131 CSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQMDL 188 >6O20-F nrPDB Length = 169 Score = 110 bits (276), Expect = 3e-25, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 69/161 (42%), Gaps = 18/161 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 25 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 77 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 78 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 133 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 134 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK 169 >2F2P-A nrPDB Length = 179 Score = 110 bits (274), Expect = 4e-25, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 69/161 (42%), Gaps = 18/161 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 57 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 58 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 113 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 114 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK 149 >4E53-A nrPDB Length = 185 Score = 107 bits (268), Expect = 2e-24, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 68/158 (43%), Gaps = 18/158 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 64 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 65 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 120 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 +L+ E +D ++ E+DID DG +N EF ++ Sbjct: 121 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 153 Score = 48.2 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D +G Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 69 Query: 167 TINLSEFQHVISRS 180 TI+ EF +++R Sbjct: 70 TIDFPEFLTMMARK 83 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 16/109 (14%), Positives = 36/109 (33%), Gaps = 19/109 (17%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP- 81 +++EI A R F + + E + L E + + + Sbjct: 89 SEEEIREAFRVFDKDGNGYISAAELRHV----------MTNLGEKLTDEEVDEMIREADI 138 Query: 82 -AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 +++E+F+ +++ K +FR G + R+ L Sbjct: 139 DGDGQVNYEEFVQMMTAKGGGGGAATKIQASFR-------GHITRKKLK 180 >5I0I-E nrPDB Length = 145 Score = 107 bits (266), Expect = 4e-24, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 69/159 (43%), Gaps = 18/159 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 3 LTEEQIAEFKEAFSLADKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 55 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 56 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL---- 111 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 +L+ E +D ++ E+DID DG +N EF +++ Sbjct: 112 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF + D D DGT+ ++L ++ L + +E++ +I+ E D D +G Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 60 Query: 167 TINLSEFQHVISRS 180 TI+ EF +++R Sbjct: 61 TIDFPEFLTMMARK 74 >6HCS-A nrPDB Length = 167 Score = 106 bits (265), Expect = 5e-24, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 69/163 (42%), Gaps = 18/163 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 57 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + ++ F +FL +++ + + AFR+FD D +G ++ +L + L Sbjct: 58 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNL---- 113 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 182 +L+ E +D ++ E+DID DG +N EF +++ + Sbjct: 114 -GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAKLE 151 Score = 26.2 bits (56), Expect = 8.3, Method: Composition-based stats. Identities = 9/85 (10%), Positives = 29/85 (34%), Gaps = 12/85 (14%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP- 81 +++EI A R F + + + + L E + + + Sbjct: 82 SEEEIREAFRVFDKD--------GNGYISAAELRHF--MTNLGEKLTDEEVDEMIREADI 131 Query: 82 -AKDSLSFEDFLDLLSVFSDTATPD 105 +++E+F+ +++ + + Sbjct: 132 DGDGQVNYEEFVQMMTAKLEGTGLE 156 >5YPX-A nrPDB Length = 223 Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 40/188 (21%), Positives = 78/188 (41%), Gaps = 11/188 (5%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 M +L+ E L + TK E+ + L +E + F IL Sbjct: 21 MSKKNQKLA-EELYKTSCQKHFTKTEVESLIICYKNL-------LEGLKMDRNLFRDILH 72 Query: 61 LPE-LKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 + + +R+ R F + +S ++++ LSVF T D K Y F +FD + Sbjct: 73 QKFNMTEDLLMDRVFRAFD-KDSDSYISLTEWVEGLSVFL-RGTLDEKMEYTFTVFDLNG 130 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 DG ++RE++ +++ + +K L++ L++ D D D ++ +F+ + Sbjct: 131 DGYISREEMFQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLI 190 Query: 180 SPDFASSF 187 P +F Sbjct: 191 EPLLLEAF 198 >5A2H-A nrPDB Length = 149 Score = 102 bits (254), Expect = 1e-22, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 11/119 (9%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 118 + L NP + + + + + ++ F +FL+L++ + + AFR+FD D Sbjct: 37 MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKD 96 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 +G ++ +L ++ L +L+ E +D ++ E+D+D DG IN EF V+ Sbjct: 97 QNGFISAAELRHVMTNL-----GEKLTDEE----VDEMIREADVDGDGQINYEEFVKVM 146 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DG + ++L ++ L + +E++ +I+ E D D +G Sbjct: 12 EFKEAFSLFDKDGDGCITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 62 Query: 167 TINLSEFQHVISRS 180 TI+ EF ++++R Sbjct: 63 TIDFPEFLNLMARK 76 >1CLM-A nrPDB Length = 148 Score = 100 bits (250), Expect = 3e-22, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 18/159 (11%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 3 ELTEEQIAEFKEAFALFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEV 55 Query: 80 -SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 + ++ F +FL L++ + + AF++FD D +G ++ +L ++ L Sbjct: 56 DADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL--- 112 Query: 139 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 +L+ E +D ++ E+DID DG IN EF ++ Sbjct: 113 --GEKLTDDE----VDEMIREADIDGDGHINYEEFVRMM 145 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D +G Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 61 Query: 167 TINLSEFQHVISRS 180 TI+ EF +++R Sbjct: 62 TIDFPEFLSLMARK 75 >2L1W-A nrPDB Length = 149 Score = 97.5 bits (241), Expect = 3e-21, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 11/119 (9%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 118 + L NP +E + + S + ++ F++FL L++ + + AF++FD D Sbjct: 36 IRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKD 95 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 +G ++ +L ++ L +L+ E++Q+I +E+D+D DG +N EF ++ Sbjct: 96 QNGYISASELRHVMINL-----GEKLTDEEVEQMI----KEADLDGDGQVNYEEFVKMM 145 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Query: 109 HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AF +FD D DG + E+L+ ++ L D + E++ +I E D D +GTI Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSL-----DQNPTEEELQDMI----SEVDADGNGTI 63 Query: 169 NLSEFQHVISRS 180 EF ++++ Sbjct: 64 EFDEFLSLMAKK 75 >1GGZ-A nrPDB Length = 148 Score = 97.5 bits (241), Expect = 3e-21, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 64/158 (40%), Gaps = 18/158 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT++++ F + + V + L NP + + + S Sbjct: 4 LTEEQVTEFKEAFSLFDKDGDGCITTRELGTV-------MRSLGQNPTEAELRDMMSEID 56 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 ++ F +FL +++ + + AFR+FD D +G ++ +L ++ L Sbjct: 57 RDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRL---- 112 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 +LS E +D ++ +D D DG +N EF V+ Sbjct: 113 -GEKLSDEE----VDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 48.2 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 33/75 (44%), Gaps = 9/75 (12%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 + AF +FD D DG + +L ++ L + L ++ E D D + Sbjct: 10 TEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRD---------MMSEIDRDGN 60 Query: 166 GTINLSEFQHVISRS 180 GT++ EF +++R Sbjct: 61 GTVDFPEFLGMMARK 75 >2E6W-A nrPDB Length = 100 Score = 97.1 bits (240), Expect = 4e-21, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNC---LTGEGEDTRLSASEMKQLIDN 155 S T K +AF ++D + DG + +E++ ++ + G L + ++ Sbjct: 2 SHMGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVER 61 Query: 156 ILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 E+ D ++DG + + EF + + SS ++ Sbjct: 62 FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQL 95 >2LMV-A nrPDB Length = 148 Score = 94.0 bits (232), Expect = 3e-20, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 70/163 (42%), Gaps = 18/163 (11%) Query: 20 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 79 + LT+++I F + + + + + + L NP + + + + Sbjct: 2 SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTL-------MRTLGQNPTEAELQDLIAE 54 Query: 80 --SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 + L+F +F +++ + + AF+IFD D DG ++ +L ++ L Sbjct: 55 AENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINL-- 112 Query: 138 EGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +++ E ID ++ E+D D DG IN EF +IS+ Sbjct: 113 ---GEKVTDEE----IDEMIREADFDGDGMINYEEFVWMISQK 148 >3QRX-A nrPDB Length = 169 Score = 93.6 bits (231), Expect = 4e-20, Method: Composition-based stats. Identities = 37/185 (20%), Positives = 76/185 (41%), Gaps = 18/185 (9%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 M + + + LT+++ F ++++ E ++ Sbjct: 1 MSYKAKTVVSARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAK-------ELKVA 53 Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 118 + L P KE I ++ S ++ FE+FL +++ + AFR+FD D Sbjct: 54 MRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDD 113 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + GT+ +DL R+ L L+ E++++I E+D + D I+ EF ++ Sbjct: 114 NSGTITIKDLRRVAKEL-----GENLTEEELQEMI----AEADRNDDNEIDEDEFIRIMK 164 Query: 179 RSPDF 183 ++ F Sbjct: 165 KTSLF 169 >3KF9-A nrPDB Length = 149 Score = 91.7 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 74/165 (44%), Gaps = 18/165 (10%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST- 79 LT+++ F ++++ E +++ L P KE I ++ + Sbjct: 1 GLTEEQKQEIREAFDLFDTDGSGTIDAK-------ELKVAMRALGFEPKKEEIKKMIADI 53 Query: 80 -SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 ++ FE+FL +++ + AFR+FD D+ G ++ ++L R+ L Sbjct: 54 DKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKEL--- 110 Query: 139 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDF 183 ++ E++++ID E+D D DG +N EF ++ ++ F Sbjct: 111 --GENMTDEELQEMID----EADRDGDGEVNEEEFFRIMKKTSLF 149 >2GGM-A nrPDB Length = 172 Score = 89.8 bits (221), Expect = 6e-19, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 74/183 (40%), Gaps = 18/183 (9%) Query: 3 GSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLP 62 + S LT+++ F +++ E +++ Sbjct: 6 KKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVK-------ELKVAMR 58 Query: 63 ELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 L P KE I ++ S ++F DFL +++ + AF++FD D+ Sbjct: 59 ALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDET 118 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 G ++ ++L R+ L L+ E++++ID E+D D DG ++ EF ++ ++ Sbjct: 119 GKISFKNLKRVAKEL-----GENLTDEELQEMID----EADRDGDGEVSEQEFLRIMKKT 169 Query: 181 PDF 183 + Sbjct: 170 SLY 172 >5D43-A nrPDB Length = 178 Score = 89.8 bits (221), Expect = 7e-19, Method: Composition-based stats. Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 11/127 (8%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFD 116 +++ L P KE + ++ S A +SF DFL +++ + AFR+FD Sbjct: 55 VAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFD 114 Query: 117 FDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 D+ G ++ ++L R+ N L L+ E++++ID E+D D DG +N EF + Sbjct: 115 DDETGKISFKNLKRVANEL-----GESLTDEELQEMID----EADRDGDGEVNEEEFLKI 165 Query: 177 ISRSPDF 183 + ++ + Sbjct: 166 MKKTNLY 172 >2OBH-A nrPDB Length = 143 Score = 83.2 bits (204), Expect = 6e-17, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 11/123 (8%) Query: 59 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFD 116 +++ L P KE I ++ S ++F DFL +++ + AF++FD Sbjct: 30 VAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFD 89 Query: 117 FDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 D+ G ++ ++L R+ L L+ E++++ID E+D D DG ++ EF + Sbjct: 90 DDETGKISFKNLKRVAKEL-----GENLTDEELQEMID----EADRDGDGEVSEQEFLRI 140 Query: 177 ISR 179 + + Sbjct: 141 MKK 143 >2M29-A nrPDB Length = 171 Score = 79.0 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 12/99 (12%) Query: 84 DSLSFEDFLDLLSVFSDTATPDI----KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + FE+F++L+S T + + AFR FD D DG + +L + L GE Sbjct: 79 GFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEP 138 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 L +E+ D +L E D++ DGTI+ EF ++S Sbjct: 139 ----LEGTEL----DEMLREMDLNGDGTIDFDEFVMMLS 169 >2LHI-A nrPDB Length = 176 Score = 78.2 bits (191), Expect = 2e-15, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 71/165 (43%), Gaps = 19/165 (11%) Query: 19 LTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFS 78 + LT+++I F S+ SS A V + L +P + + + + Sbjct: 2 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATV-------MRSLGLSPSEAEVNDLMN 54 Query: 79 T--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 + F +FL L+S + + + AF++FD + DG ++ +L ++ + Sbjct: 55 EIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI- 113 Query: 137 GEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 +L+ +E +D++L E D G IN+ +F ++S+ Sbjct: 114 ----GEKLTDAE----VDDMLREV-SDGSGEINIQQFAALLSKGS 149 >4JWQ-A nrPDB Length = 199 Score = 77.1 bits (188), Expect = 4e-15, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 64/154 (41%), Gaps = 14/154 (9%) Query: 26 EILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDS 85 ++ F L + ++ + + L LP+ + + S Sbjct: 56 DLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQ-----NFDVLLDQID-SDGSGR 109 Query: 86 LSFEDFLDLLSVFSDTATPDIKSHY-AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 + + +F L+ D K Y AFR+FD D+DG + +L+ ++ +G T+ Sbjct: 110 IDYTEF---LAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQK 166 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 +++K++I +E D + DG I+ EF ++ Sbjct: 167 DVNQVKKMI----QEVDKNNDGKIDFYEFCEMMK 196 >3O4Y-A nrPDB Length = 196 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 32/156 (20%), Positives = 63/156 (40%), Gaps = 14/156 (8%) Query: 26 EILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDS 85 ++ F L + + ++ + L LP P + + S + Sbjct: 53 DVQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLP-----PNFDLLLDQID-SDGSGN 106 Query: 86 LSFEDFLDLLSVFSDTATPDIKSHY-AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 + + +F L+ D K Y AFR+FD D+DG + +L+ ++ G T Sbjct: 107 IDYTEF---LAAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRGNITER 163 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 +++K++I E D + DG I+ EF ++ + Sbjct: 164 DVNQVKKMI----REVDKNGDGKIDFYEFSEMMKLT 195 >5E37-A nrPDB Length = 356 Score = 74.0 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASE-MKQLIDNILEESDIDR 164 + F++ D D +G ++RE+L L+ + GE +S + ++ +E+ D+++ Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESME-SGEVYMMSQHWLPEDELERCMEQYDVNK 87 Query: 165 DGTINLSEFQHVISRSPDFASSF 187 DG I+ EF+ +I + Sbjct: 88 DGVISFEEFKQIIYDGLLLEGTL 110 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 28/165 (16%), Positives = 55/165 (33%), Gaps = 15/165 (9%) Query: 23 TKQEILLAHRRFCELLPQEQRSVES----SLRAQVPFEQILSL-PELKANPFKERICRVF 77 +K ++ RRF ++ +L + ++ + ER + Sbjct: 24 SKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQY 83 Query: 78 STSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 + +SFE+F ++ + AF+ D +GT+ +LS+L L Sbjct: 84 DVN-KDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGN 142 Query: 138 EGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 182 +L +++ D D G I EF + S Sbjct: 143 PVSLEKLVD---------LMQMYDKDDSGQIEFPEFLLMFRNSLL 178 >1LKJ-A nrPDB Length = 146 Score = 73.2 bits (178), Expect = 6e-14, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 69/163 (42%), Gaps = 19/163 (11%) Query: 19 LTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFS 78 + LT+++I F S+ SS A V + L +P + + + + Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATV-------MRSLGLSPSEAEVNDLMN 53 Query: 79 T--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 + F +FL L+S + + + AF++FD + DG ++ +L ++ + Sbjct: 54 EIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI- 112 Query: 137 GEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 +L+ +E+ ++ + D G IN+ +F ++S+ Sbjct: 113 ----GEKLTDAEVDDMLREV-----SDGSGEINIQQFAALLSK 146 >4DS7-A nrPDB Length = 147 Score = 72.1 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 19/163 (11%) Query: 19 LTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFS 78 LT+++I F S+ +S A V + L +P + + + + Sbjct: 2 SQNLTEEQIAEFKEAFALFDKDNSGSISASELATV-------MRSLGLSPSEAEVADLMN 54 Query: 79 T--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 ++ F +FL L+S + + AF++FD + DG ++ +L ++ + Sbjct: 55 EIDVDGNHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI- 113 Query: 137 GEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 +L+ +E +D +L E D G IN+ +F ++S+ Sbjct: 114 ----GEKLTDAE----VDEMLREV-SDGSGEINIKQFAALLSK 147 >1DTL-A nrPDB Length = 161 Score = 72.1 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 50/123 (40%), Gaps = 14/123 (11%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT---ATPDIKSHYAFRIF 115 + L NP E + + ++ F++FL ++ + + FR+F Sbjct: 45 MRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMF 104 Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D + DG ++ E+L ++ + + I+ ++++ D + DG I+ EF Sbjct: 105 DKNADGYIDLEELKIMLQAT---------GETITEDDIEELMKDGDKNNDGRIDYDEFLE 155 Query: 176 VIS 178 + Sbjct: 156 FMK 158 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 10/86 (11%) Query: 96 SVFSDTATPDIKSHYAFRIFDFD-DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 +V T + AF IF +DG+++ ++L +++ L + E++++ID Sbjct: 8 AVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-----GQNPTPEELQEMID 62 Query: 155 NILEESDIDRDGTINLSEFQHVISRS 180 E D D GT++ EF ++ RS Sbjct: 63 ----EVDEDGSGTVDFDEFLVMMVRS 84 Score = 35.5 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 40/107 (37%), Gaps = 6/107 (5%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 +F S+S ++ ++ + TP+ D D GT++ ++ ++ Sbjct: 24 FDIFVLGAEDGSISTKELGKVMRMLGQNPTPEE-LQEMIDEVDEDGSGTVDFDEFLVMMV 82 Query: 134 CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 + + + ++ D + DG I+L E + ++ + Sbjct: 83 RSMKDDSKGKSEEE-----LSDLFRMFDKNADGYIDLEELKIMLQAT 124 >3K21-A nrPDB Length = 191 Score = 72.1 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 59/154 (38%), Gaps = 14/154 (9%) Query: 26 EILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDS 85 ++ F L + + + + L LP + ++I S Sbjct: 50 DVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPY-NFDLLLDQI-----DSDGSGK 103 Query: 86 LSFEDFLDLLSVFSDTATPDIKSHY-AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL 144 + + +F+ + D K Y AFR+FD D+DG + +L+ ++ +G T+ Sbjct: 104 IDYTEFI---AAALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQR 160 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + ++ + D + DG I+ EF ++ Sbjct: 161 DV----NRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 >5JN2-A nrPDB Length = 525 Score = 72.1 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 67/164 (40%), Gaps = 20/164 (12%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPE-----LKANPFKERICRVF 77 ++ E F ++ ++ + + +++++ + L A+ + + +V Sbjct: 371 SQDETKELTAIFHKMDKNGDGQLDRAELIE-GYKELMRMKGQDASMLDASAVEHEVDQVL 429 Query: 78 STSP--AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 + + +F+ +++ T + AFR+FD D+ G ++ +L+ + Sbjct: 430 DAVDFDKNGYIEYSEFVT-VAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIF--- 485 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G S + ++L E D + DG ++ EFQ ++ + Sbjct: 486 ---GVSDVDSETW-----KSVLSEVDKNNDGEVDFDEFQQMLLK 521 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 2/100 (2%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED--TRLSASEM 149 L + + + F D + DG L+R +L L + L AS + Sbjct: 362 LLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAV 421 Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 + +D +L+ D D++G I SEF V S ++ Sbjct: 422 EHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERL 461 Score = 34.3 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 16/123 (13%), Positives = 34/123 (27%), Gaps = 19/123 (15%) Query: 79 TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRI----------FDFDDDGTLNREDL 128 L + ++ D A + DFD +G + + Sbjct: 386 DKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEF 445 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 + ++ ++ D D G I+ +E + S + ++K Sbjct: 446 VTVAMDRKTLLS---------RERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWK 496 Query: 189 IVL 191 VL Sbjct: 497 SVL 499 >1TOP-A nrPDB Length = 162 Score = 72.1 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 54/123 (43%), Gaps = 14/123 (11%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT---ATPDIKSHYAFRIF 115 + L NP KE + + ++ FE+FL ++ + + FRIF Sbjct: 46 MRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIF 105 Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D + DG ++ E+L ++ ++ I++++++SD + DG I+ EF Sbjct: 106 DKNADGFIDIEELGEILRAT---------GEHVTEEDIEDLMKDSDKNNDGRIDFDEFLK 156 Query: 176 VIS 178 ++ Sbjct: 157 MME 159 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D G ++ ++L ++ L K+ +D I+EE D D G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPT---------KEELDAIIEEVDEDGSG 71 Query: 167 TINLSEFQHVISR 179 TI+ EF ++ R Sbjct: 72 TIDFEEFLVMMVR 84 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/107 (13%), Positives = 34/107 (31%), Gaps = 7/107 (6%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 +F +S ++ ++ + D D GT++ E+ ++ Sbjct: 26 FDMFDADGG-GDISTKELGTVM-RMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMV 83 Query: 134 CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 E + + N D + DG I++ E ++ + Sbjct: 84 RQMKEDAKGKSEEE-----LANCFRIFDKNADGFIDIEELGEILRAT 125 >2HF5-A nrPDB Length = 68 Score = 71.7 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 71 ERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 + + + + ++ F +FL +++ + + AFR+FD D +G ++ +L Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 129 SRLVNCL 135 ++ L Sbjct: 61 RHVMTNL 67 >2LAP-A nrPDB Length = 167 Score = 71.7 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 53/125 (42%), Gaps = 14/125 (11%) Query: 61 LPELKANPFKERICRVFSTSPAK--DSLSFEDFLDLLSVFSDTATPDI----KSHYAFRI 114 + + P + + + + F+DF++L+ T D+ + AFR Sbjct: 51 MRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFRE 110 Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD + DG ++ +L + L G R I+ I+ + D++ DG ++ EF Sbjct: 111 FDTNGDGEISTSELREAMRKLLGHQVGHRD--------IEEIIRDVDLNGDGRVDFEEFV 162 Query: 175 HVISR 179 ++SR Sbjct: 163 RMMSR 167 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 38/97 (39%), Gaps = 11/97 (11%) Query: 92 LDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEM 149 L LS + P+ + AFR FD D DG +N DL + + + L Sbjct: 9 LRNLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIE--- 65 Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 + ++ +++ G ++ +F ++ ++ Sbjct: 66 ------LSQQINMNLGGHVDFDDFVELMGPKLLAETA 96 >2TN4-A nrPDB Length = 159 Score = 71.3 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 53/123 (43%), Gaps = 14/123 (11%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT---ATPDIKSHYAFRIF 115 + L P KE + + ++ FE+FL ++ + + FRIF Sbjct: 43 MRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIF 102 Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D + DG ++ E+L+ + ++ E I++++++ D + DG I+ EF Sbjct: 103 DRNADGYIDAEELAEIFRA-----SGEHVTDEE----IESLMKDGDKNNDGRIDFDEFLK 153 Query: 176 VIS 178 ++ Sbjct: 154 MME 156 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D G ++ ++L ++ L + K+ +D I+EE D D G Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMRM---------LGQTPTKEELDAIIEEVDEDGSG 68 Query: 167 TINLSEFQHVISR 179 TI+ EF ++ R Sbjct: 69 TIDFEEFLVMMVR 81 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/107 (13%), Positives = 32/107 (29%), Gaps = 7/107 (6%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 +F +S ++ ++ + D D GT++ E+ ++ Sbjct: 23 FDMFDADGG-GDISVKELGTVM-RMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMV 80 Query: 134 CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 E + + + D + DG I+ E + S Sbjct: 81 RQMKEDAKGKSEEE-----LAELFRIFDRNADGYIDAEELAEIFRAS 122 >4YZB-A nrPDB Length = 491 Score = 70.5 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 63/163 (38%), Gaps = 18/163 (11%) Query: 23 TKQEILLAHRRFCELLP--QEQRSVESSLRAQVPFEQILS--LPELKANPFKERICRVFS 78 T +E + ++ F + Q + + V ++ + L + + + +V Sbjct: 334 TNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLD 393 Query: 79 TSPAKDSLSFEDFLDLLSVFSDTATP--DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 D F ++ + ++V D T + AF +FD D G ++ +L+ + Sbjct: 394 AVDF-DKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIF---- 448 Query: 137 GEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G S + +L E D + DG ++ EF+ ++ + Sbjct: 449 --GVSEVDSETW-----RRVLAEVDRNNDGEVDFEEFRQMLLK 484 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 2/100 (2%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR-LVNCLTGEGEDTR-LSASEM 149 L + T ++ + F+ D + DG L++++L V + +GED L S + Sbjct: 325 LLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAI 384 Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 + ++ +L+ D D++G I SEF V S ++ Sbjct: 385 EFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRL 424 Score = 31.2 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 18/123 (14%), Positives = 37/123 (30%), Gaps = 19/123 (15%) Query: 79 TSPAKDSLSFEDFLDLLSVFSDTATPD----IKSHYAFRI------FDFDDDGTLNREDL 128 L ++ ++ D +S F + DFD +G + + Sbjct: 349 DKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEF 408 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 + +Q ++ D D G I+ SE + S + +++ Sbjct: 409 VTVAMDRKTLLS---------RQRLERAFGMFDADGSGKISSSELATIFGVSEVDSETWR 459 Query: 189 IVL 191 VL Sbjct: 460 RVL 462 >1FW4-A nrPDB Length = 71 Score = 70.1 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 9/80 (11%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 + + AFR+FD D +G ++ +L ++ L +L+ E +D ++ E+ Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE----VDEMIREA 51 Query: 161 DIDRDGTINLSEFQHVISRS 180 DID DG +N EF +++ Sbjct: 52 DIDGDGQVNYEEFVQMMTAK 71 Score = 30.1 bits (66), Expect = 0.60, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 24/70 (34%), Gaps = 2/70 (2%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 + RVF +S + +++ D + R D D DG +N Sbjct: 3 DSEEEIREAFRVFD-KDGNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVN 60 Query: 125 REDLSRLVNC 134 E+ +++ Sbjct: 61 YEEFVQMMTA 70 >3FWC-A nrPDB Length = 161 Score = 70.1 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 68/182 (37%), Gaps = 23/182 (12%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 M + S L L + L +++ + F + ++ Sbjct: 1 MSKNRSSLQSGPL-----NSELLEEQKQEIYEAFSLFDMN-----NDGFLDYHELK--VA 48 Query: 61 LPELKANPFKERICRVFSTSPAKDS--LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 118 + L K I + ++ + ++DF ++ P + AF++FD D Sbjct: 49 MKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDD 108 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 G ++ ++L R+ L L+ E++ +I+ D+D DG IN +EF + + Sbjct: 109 HTGKISIKNLRRVAKEL-----GETLTDEELRAMIEEF----DLDGDGEINENEFIAICT 159 Query: 179 RS 180 S Sbjct: 160 DS 161 >4RGJ-A nrPDB Length = 520 Score = 69.7 bits (169), Expect = 6e-13, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 62/165 (37%), Gaps = 22/165 (13%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPF--------KERIC 74 T E + F ++ ++ + + ++++L L + ++I Sbjct: 366 TIDETKELTKIFKKMDKNGDGQLDRNELI-IGYKELLKLKGEDTSDLDNAAIEYEVDQIL 424 Query: 75 RVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNC 134 + + +FL +S+ + AF++FD D G ++ +L++L Sbjct: 425 NSIDLDQ-NGYIEYSEFLT-VSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFGL 482 Query: 135 LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 E + +L+E D + DG I+ EF+ ++ + Sbjct: 483 SDVSSECWK-----------TVLKEVDQNNDGEIDFKEFRDMLVK 516 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 41/100 (41%), Gaps = 2/100 (2%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED--TRLSASEM 149 L + T + F+ D + DG L+R +L L + + L + + Sbjct: 357 LLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAI 416 Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 + +D IL D+D++G I SEF V S+ ++ Sbjct: 417 EYEVDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERL 456 Score = 33.5 bits (75), Expect = 0.059, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 25/76 (32%), Gaps = 9/76 (11%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D D +G + + LS ++ + D D G I+ +E Sbjct: 428 DLDQNGYIEYSEFL-----TVSIDRKLLLSTE----RLEKAFKLFDKDGSGKISANELAQ 478 Query: 176 VISRSPDFASSFKIVL 191 + S + +K VL Sbjct: 479 LFGLSDVSSECWKTVL 494 >1M39-A nrPDB Length = 89 Score = 69.7 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 9/98 (9%) Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 ++F DFL +++ + AF++FD D+ G ++ ++L R+ L L+ Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-----GENLT 55 Query: 146 ASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDF 183 E++++ID E+D D DG ++ EF ++ ++ + Sbjct: 56 DEELQEMID----EADRDGDGEVSEQEFLRIMKKTSLY 89 >4MVF-A nrPDB Length = 506 Score = 69.4 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 13/154 (8%) Query: 26 EILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDS 85 EI F L ++ S Q + + + K P ++ R ++ A Sbjct: 358 EINNLRNIFIALDVDNSGTLSS----QEILDGLKKIGYQKIPPDIHQVLRDIDSN-ASGQ 412 Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 + + DFL ++ T F+ FD D +G ++ E+L R+ + Sbjct: 413 IHYTDFLAA-TIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIF-------GRDDIE 464 Query: 146 ASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + + ID++L+E D++ DG I+ EF ++S+ Sbjct: 465 NPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 498 Score = 31.6 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 16/109 (14%), Positives = 40/109 (36%), Gaps = 4/109 (3%) Query: 31 HRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRV---FSTSPAKDSLS 87 +++ + Q R ++S+ Q+ + L+ K K+ +C + F +S Sbjct: 391 YQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKIS 450 Query: 88 FEDFLDLLSVFSDTATPDIK-SHYAFRIFDFDDDGTLNREDLSRLVNCL 135 E+ + K + D + DG ++ + +++ L Sbjct: 451 VEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKL 499 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 28/77 (36%), Gaps = 9/77 (11%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 F D D+ GTL+ +++ + + ++ I +L + D + G Sbjct: 362 LRNIFIALDVDNSGTLSSQEILDGLKKI----GYQKIPPD-----IHQVLRDIDSNASGQ 412 Query: 168 INLSEFQHVISRSPDFA 184 I+ ++F + Sbjct: 413 IHYTDFLAATIDKQTYL 429 >2KZ2-A nrPDB Length = 94 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 9/83 (10%) Query: 98 FSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNIL 157 + + AFR+ D D +G ++ +L ++ L +L+ E +D ++ Sbjct: 21 LMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNL-----GEKLTDEE----VDEMI 71 Query: 158 EESDIDRDGTINLSEFQHVISRS 180 E+DID DG +N EF +++ Sbjct: 72 READIDGDGQVNYEEFVQMMTAK 94 Score = 27.8 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 24/67 (35%), Gaps = 3/67 (4%) Query: 70 KERICRVF--STSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRED 127 +E I F +S + +++ D + R D D DG +N E+ Sbjct: 28 EEEIREAFRVEDKDGNGYISAAELRHVMTNL-GEKLTDEEVDEMIREADIDGDGQVNYEE 86 Query: 128 LSRLVNC 134 +++ Sbjct: 87 FVQMMTA 93 >2KN2-A nrPDB Length = 92 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 9/79 (11%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 + + AF++FD D +G ++ +L ++ L +L+ E++Q+I + Sbjct: 2 HMDTDAEEELKEAFKVFDKDQNGYISASELRHVMINL-----GEKLTDEEVEQMI----K 52 Query: 159 ESDIDRDGTINLSEFQHVI 177 E+D+D DG +N EF ++ Sbjct: 53 EADLDGDGQVNYEEFVKMM 71 Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 2/69 (2%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 A + +VF +S + L + + D + + D D DG +N Sbjct: 6 DAEEELKEAFKVFD-KDQNGYISASE-LRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 63 Query: 125 REDLSRLVN 133 E+ +++ Sbjct: 64 YEEFVKMMM 72 >3PM8-A nrPDB Length = 197 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 13/155 (8%) Query: 26 EILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDS 85 EI F L ++ S Q + + + K P ++ R ++ A Sbjct: 55 EINNLRNIFIALDVDNSGTLSS----QEILDGLKKIGYQKIPPDIHQVLRDIDSN-ASGQ 109 Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 + + DFL ++ T F+ FD D +G ++ E+L R+ + Sbjct: 110 IHYTDFLAA-TIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIF-------GRDDIE 161 Query: 146 ASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 + + ID++L+E D++ DG I+ EF ++S+ Sbjct: 162 NPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKK 196 Score = 27.0 bits (58), Expect = 5.9, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 28/77 (36%), Gaps = 9/77 (11%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 F D D+ GTL+ +++ + + ++ I +L + D + G Sbjct: 59 LRNIFIALDVDNSGTLSSQEILDGLKKI----GYQKIPPD-----IHQVLRDIDSNASGQ 109 Query: 168 INLSEFQHVISRSPDFA 184 I+ ++F + Sbjct: 110 IHYTDFLAATIDKQTYL 126 >2M5E-A nrPDB Length = 73 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 9/79 (11%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 + + AF++FD D +G ++ +L ++ L +L+ E +D ++ Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-----GEKLTDDE----VDEMIR 51 Query: 159 ESDIDRDGTINLSEFQHVI 177 E+DID DG IN EF ++ Sbjct: 52 EADIDGDGHINYEEFVRMM 70 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 26/74 (35%), Gaps = 2/74 (2%) Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 + E + +VF +S + +++ D + R D D D Sbjct: 1 MKEQDSEEELIEAFKVFD-RDGNGLISAAELRHVMTNL-GEKLTDDEVDEMIREADIDGD 58 Query: 121 GTLNREDLSRLVNC 134 G +N E+ R++ Sbjct: 59 GHINYEEFVRMMVS 72 >2RO9-A nrPDB Length = 69 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 9/75 (12%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDI 162 + + AFR+FD D +G ++ +L ++ L +L+ E +D ++ E+D+ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-----GEKLTDEE----VDEMIREADV 51 Query: 163 DRDGTINLSEFQHVI 177 D DG IN EF V+ Sbjct: 52 DGDGQINYEEFVKVM 66 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 25/70 (35%), Gaps = 2/70 (2%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 + + RVF +S + +++ D + R D D DG +N Sbjct: 1 DSEEELKEAFRVFD-KDQNGFISAAELRHVMTNL-GEKLTDEEVDEMIREADVDGDGQIN 58 Query: 125 REDLSRLVNC 134 E+ +++ Sbjct: 59 YEEFVKVMMA 68 >5ZOR-A nrPDB Length = 149 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 10/108 (9%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 ER R +T+ A + + +F ++ + AF++FD D G ++ +L Sbjct: 46 VERTVRSMNTN-ANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLK 104 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + L ++++I E+D D DG ++ EF+ V+ Sbjct: 105 EVAKLL-----GENPGDDVLQEMI----AEADEDGDGEVSFEEFKSVM 143 Score = 35.5 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 13/107 (12%), Positives = 36/107 (33%), Gaps = 9/107 (8%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F ++ E+ + P + R + + +G + + R+ Sbjct: 11 EAFNLFDA-DGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEFERM 69 Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 V R++ + + + + D+D+ G I+ + + V Sbjct: 70 VKS--------RMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAK 108 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 35/97 (36%), Gaps = 4/97 (4%) Query: 44 SVESSLRAQVPFEQILSLPELKANPFKERICRVF--STSPAKDSLSFEDFLDLLSVFSDT 101 + + L FE+++ + E + + F K +SF + L ++ Sbjct: 55 TNANGLIEYGEFERMVKSR-MAQKDSPEEVLKAFQLFDLDKKGKISFAN-LKEVAKLLGE 112 Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 D D D DG ++ E+ ++ + G+ Sbjct: 113 NPGDDVLQEMIAEADEDGDGEVSFEEFKSVMMQMRGK 149 >3HZT-A nrPDB Length = 467 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 55/164 (33%), Gaps = 20/164 (12%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL-------SLPELKANPFKERICR 75 T +E + F +L ++ + + + L + + I + Sbjct: 309 TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQ 368 Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 + + +F+ + + AF+ FD D G + E+L RL Sbjct: 369 SVDF-DRNGYIEYSEFVTVCMDKQLL-LSRERLLAAFQQFDSDGSGKITNEELGRLF--- 423 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G + + +L+E D + DG ++ EF ++ + Sbjct: 424 ---GVTEVDDETWHQ-----VLQECDKNNDGEVDFEEFVEMMQK 459 Score = 49.7 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 2/101 (1%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT--GEGEDTRLSASEM 149 + + T + FR D + DG L+R++L L + L +S++ Sbjct: 300 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQI 359 Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKIV 190 + +D+IL+ D DR+G I SEF V S +++ Sbjct: 360 EAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLL 400 Score = 26.2 bits (56), Expect = 8.7, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 5/67 (7%) Query: 71 ERICRVF--STSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 ER+ F S ++ E+ L V D H + D ++DG ++ E+ Sbjct: 397 ERLLAAFQQFDSDGSGKITNEELGRLFGVTEVD---DETWHQVLQECDKNNDGEVDFEEF 453 Query: 129 SRLVNCL 135 ++ + Sbjct: 454 VEMMQKI 460 >3NCG-A nrPDB Length = 486 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 66/158 (41%), Gaps = 24/158 (15%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 L + E++ + F L + S+ + + + + +P L Sbjct: 348 LDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDM--------------D 393 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 S+ + +F+ ++ + AF++FD D G ++ ++L +L Sbjct: 394 GSGSIEYSEFIAS-AIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLF--------- 443 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 ++ +S + +++I+E+ D ++DG ++ +EF ++ Sbjct: 444 SQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQN 481 Score = 39.7 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 5/88 (5%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR-----LVNCLTGEGEDTRLSA 146 L ++ T + FR D ++DG L+R++L R + + Sbjct: 317 LLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEG 376 Query: 147 SEMKQLIDNILEESDIDRDGTINLSEFQ 174 S ++ ID+++ D+D G+I SEF Sbjct: 377 STIEDQIDSLMPLLDMDGSGSIEYSEFI 404 Score = 35.5 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 22/184 (11%), Positives = 50/184 (27%), Gaps = 38/184 (20%) Query: 28 LLAHRRFCELLP--QEQRSVESSLRAQVPFEQILSLPE------------LKANPFKERI 73 +++ P + S+ES++ F+ L + L I Sbjct: 277 HPWIQKYSSETPTISDLPSLESAMTNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEI 336 Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSD-------------TATPDIKSHYAFRIFDFDDD 120 R T+ L ++ + F +T + + + D D Sbjct: 337 FRKLDTN-NDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDGS 395 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSE-FQHVISR 179 G++ + + ++ ++ + D D G I+ E F+ Sbjct: 396 GSIEYSEF---------IASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSQA 446 Query: 180 SPDF 183 Sbjct: 447 DSSI 450 Score = 29.7 bits (65), Expect = 0.86, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 33/104 (31%), Gaps = 11/104 (10%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 M GSGS E +A D T L +E R F + + E Sbjct: 392 MDGSGSIEYSEFIASAIDRTILLSRE--RMERAFKMFDKDGSGKISTK-------ELFKL 442 Query: 61 LPELKANPFKERICRVFSTSPAK--DSLSFEDFLDLLSVFSDTA 102 + ++ E + + + F +F+++L F Sbjct: 443 FSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQNFVRNE 486 >2LHH-A nrPDB Length = 128 Score = 64.7 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 52/129 (40%), Gaps = 9/129 (6%) Query: 19 LTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFS 78 + LT+++I F S+ SS A V + L +P + + + + Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATV-------MRSLGLSPSEAEVNDLMN 53 Query: 79 T--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 + F +FL L+S + + + AF++FD + DG ++ +L ++ + Sbjct: 54 EIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIG 113 Query: 137 GEGEDTRLS 145 + D L Sbjct: 114 EKLTDAELE 122 Score = 43.2 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 38/73 (52%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D++G+++ +L+ ++ L + +++++ E D+D + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPS---------EAEVNDLMNEIDVDGNH 61 Query: 167 TINLSEFQHVISR 179 I SEF ++SR Sbjct: 62 QIEFSEFLALMSR 74 >2ROB-A nrPDB Length = 70 Score = 63.6 bits (153), Expect = 4e-11, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 9/75 (12%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDI 162 + + AF++FD D +G ++ +L ++ L +L+ E++Q+I +E+D+ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINL-----GEKLTDEEVEQMI----KEADL 51 Query: 163 DRDGTINLSEFQHVI 177 D DG +N EF ++ Sbjct: 52 DGDGQVNYEEFVKMM 66 Score = 27.4 bits (59), Expect = 4.1, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 2/69 (2%) Query: 65 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 124 A + +VF +S + L + + D + + D D DG +N Sbjct: 1 DAEEELKEAFKVFD-KDQNGYISASE-LRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 58 Query: 125 REDLSRLVN 133 E+ +++ Sbjct: 59 YEEFVKMMM 67 >2JNF-A nrPDB Length = 158 Score = 63.6 bits (153), Expect = 5e-11, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 46/111 (41%), Gaps = 14/111 (12%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTA----TPDIKSHYAFRIFDFDDDGTLNRED 127 ++ F + F+ F + + F + AFR++D + +G ++ + Sbjct: 54 QLIDEFDP-FGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDV 112 Query: 128 LSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + ++ L + + +D +++E D D GT++ EF V++ Sbjct: 113 MREIL---------AELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >1S6I-A nrPDB Length = 188 Score = 61.7 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 27/161 (16%), Positives = 60/161 (37%), Gaps = 21/161 (13%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTS 80 L+++EI F + + S + L + + + I + + Sbjct: 3 RLSEEEIGGLKELFKMID-----TDNSGTITFDELKD--GLKRVGSELMESEIKDLMDAA 55 Query: 81 P--AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 ++ + +F+ +V + + AF FD D G + +++ + Sbjct: 56 DIDKSGTIDYGEFIAA-TVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQA------- 107 Query: 139 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 +D L ID++++E D D DG I+ EF ++ + Sbjct: 108 CKDFGLDD----IHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 >5MWC-D nrPDB Length = 311 Score = 60.9 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 9/77 (11%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDI 162 + + FR FD D DG ++RE+ ++ +L+ + D I +SD Sbjct: 148 PSEEELSECFRTFDKDGDGFIDREEFGGIIRL-----TGEQLTDEDP----DEIFGDSDT 198 Query: 163 DRDGTINLSEFQHVISR 179 D++G I+ EF ++ Sbjct: 199 DKNGRIDFDEFLKMVEN 215 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 22/65 (33%), Gaps = 2/65 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 R F + E+F + + D F D D +G ++ ++ ++ Sbjct: 155 ECFRTFD-KDGDGFIDREEF-GGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKM 212 Query: 132 VNCLT 136 V + Sbjct: 213 VENVQ 217 Score = 30.4 bits (67), Expect = 0.44, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 16/46 (34%), Gaps = 4/46 (8%) Query: 135 LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 + S E+ + D D DG I+ EF +I + Sbjct: 139 MANSLTAMVPSEEELSE----CFRTFDKDGDGFIDREEFGGIIRLT 180 >2LV7-A nrPDB Length = 100 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 35/76 (46%), Gaps = 9/76 (11%) Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESD 161 + AF++FD D +G +++++L + L + L + I++ D Sbjct: 32 EDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVEL---------EVIIQRLD 82 Query: 162 IDRDGTINLSEFQHVI 177 +D DG ++ EF ++ Sbjct: 83 MDGDGQVDFEEFVTLL 98 >2AAO-A nrPDB Length = 166 Score = 60.1 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 56/140 (40%), Gaps = 15/140 (10%) Query: 45 VESSLRAQVPFEQILS-LPELKANPFKERICRVF--STSPAKDSLSFEDFLDLLSVFSDT 101 +++ Q+ FE++ + L + AN + I + + ++ +++F+ + Sbjct: 36 IDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKEFIAATLHLNKI 95 Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESD 161 D AF FD D G + ++L + E I+ ++ + D Sbjct: 96 EREDH-LFAAFTYFDKDGSGYITPDELQQACEEFGVE-----------DVRIEELMRDVD 143 Query: 162 IDRDGTINLSEFQHVISRSP 181 D DG I+ +EF ++ + Sbjct: 144 QDNDGRIDYNEFVAMMQKGS 163 >3LIJ-A nrPDB Length = 494 Score = 59.7 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 19/161 (11%), Positives = 55/161 (34%), Gaps = 17/161 (10%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRA----QVPFEQILSLPELKANPFKERICRVFS 78 +++E F + ++ ++ E++ + + I Sbjct: 341 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 400 Query: 79 TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 + + +F+ +++ + K AF+ FD D +G ++ ++L+ + Sbjct: 401 F-DRNGYIDYSEFVT-VAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGL---- 454 Query: 139 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + ++ D + DG ++ EF +I + Sbjct: 455 -------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 488 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQ 151 L ++ + + FR D + DG L+R++L + L+GE E +++ Sbjct: 332 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGE-EVAVFDLPQIES 390 Query: 152 LIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 +D IL +D DR+G I+ SEF V S K+ Sbjct: 391 EVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKL 428 >6IIE-A nrPDB Length = 93 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 41/77 (53%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 + P+ K + F+++D D +G L+ ++ +++ + E SE++ ++ +++ Sbjct: 2 MEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 159 ESDIDRDGTINLSEFQH 175 E D D G+++ +E+ Sbjct: 62 EIDYDGSGSVSQAEWVR 78 >3KHE-A nrPDB Length = 191 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 55/164 (33%), Gaps = 20/164 (12%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL-------SLPELKANPFKERICR 75 T +E + F +L ++ + + + L + + I + Sbjct: 35 TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQ 94 Query: 76 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 + + +F+ + + AF+ FD D G + E+L RL Sbjct: 95 SVDF-DRNGYIEYSEFVTVCMDKQLL-LSRERLLAAFQQFDSDGSGKITNEELGRLF--- 149 Query: 136 TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 G + + +L+E D + DG ++ EF ++ + Sbjct: 150 ---GVTEVDDETWHQ-----VLQECDKNNDGEVDFEEFVEMMQK 185 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 2/101 (1%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT--GEGEDTRLSASEM 149 + + T + FR D + DG L+R++L L + L +S++ Sbjct: 26 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQI 85 Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKIV 190 + +D+IL+ D DR+G I SEF V S +++ Sbjct: 86 EAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLL 126 >2K2I-A nrPDB Length = 79 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 43/88 (48%), Gaps = 9/88 (10%) Query: 96 SVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDN 155 + + AF++FD D+ G ++ ++L R+ L L+ E++++ID Sbjct: 1 TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-----GENLTDEELQEMID- 54 Query: 156 ILEESDIDRDGTINLSEFQHVISRSPDF 183 E+D D DG ++ EF ++ ++ + Sbjct: 55 ---EADRDGDGEVSEQEFLRIMKKTSLY 79 Score = 27.0 bits (58), Expect = 4.9, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 28/74 (37%), Gaps = 3/74 (4%) Query: 62 PELKANPFKERICRVF--STSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 ++ KE I + F +SF++ L ++ D + D D Sbjct: 2 QKMSEKDTKEEILKAFKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDEADRDG 60 Query: 120 DGTLNREDLSRLVN 133 DG ++ ++ R++ Sbjct: 61 DGEVSEQEFLRIMK 74 >3Q5I-A nrPDB Length = 504 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 57/159 (35%), Gaps = 13/159 (8%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPA 82 T +E F +L ++ + EL E Sbjct: 350 TLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVD 409 Query: 83 KDSLSFEDFLDLLSVFSDTATP--DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 D + ++ + +SV D + + AF +FD D G + +E+L+ L Sbjct: 410 FDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGLT----- 464 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 S ++ +++L E+D ++D I+ EF ++ + Sbjct: 465 ------SISEKTWNDVLGEADQNKDNMIDFDEFVSMMHK 497 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTG-EGEDTRLSASEMK 150 + + T + F+ D + DG L++++L N L + E L ++ Sbjct: 341 ILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKN--VE 398 Query: 151 QLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 + +DNIL+E D D++G I SEF V S ++ Sbjct: 399 EEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERL 437 Score = 33.9 bits (76), Expect = 0.039, Method: Composition-based stats. Identities = 16/126 (12%), Positives = 38/126 (30%), Gaps = 17/126 (13%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFS-------DTATPDIKSHYAFRIFDFDDDGTLNR 125 I + + L ++ ++ +V + + + + DFD +G + Sbjct: 360 IFKKLDKN-GDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKNGYIEY 418 Query: 126 EDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFAS 185 + + + RL D D+ G I E ++ + Sbjct: 419 SEFISVCMDKQILFSEERLR---------RAFNLFDTDKSGKITKEELANLFGLTSISEK 469 Query: 186 SFKIVL 191 ++ VL Sbjct: 470 TWNDVL 475 >2B1U-A nrPDB Length = 71 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 9/75 (12%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 AFR FD D DG + ++L R + G G+ ++ +D ++ E+D+D+D Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRR---AMAGLGQPL------PQEELDAMIREADVDQD 56 Query: 166 GTINLSEFQHVISRS 180 G +N EF ++++ Sbjct: 57 GRVNYEEFARMLAQE 71 Score = 29.3 bits (64), Expect = 0.93, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 R F ++ ++ ++ P + R D D DG +N E+ +R++ Sbjct: 12 FRAFDQ-DGDGHITVDELRRAMAGL-GQPLPQEELDAMIREADVDQDGRVNYEEFARML 68 >1OQP-A nrPDB Length = 77 Score = 57.0 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 9/85 (10%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 S + AFR+FD D+ GT+ +DL R+ L L+ E++++I Sbjct: 2 SGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKEL-----GENLTEEELQEMI----A 52 Query: 159 ESDIDRDGTINLSEFQHVISRSPDF 183 E+D + D I+ EF ++ ++ F Sbjct: 53 EADRNDDNEIDEDEFIRIMKKTSLF 77 >3L19-A nrPDB Length = 214 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 39/99 (39%), Gaps = 12/99 (12%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 + + +F+ +++ + K AF+ FD D +G ++ ++L+ + Sbjct: 119 DRNGYIDYSEFVT-VAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGL------ 171 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + ++ D + DG ++ EF +I + Sbjct: 172 -----DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 205 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Query: 92 LDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQ 151 L ++ + + FR D + DG L+R++L + L+GE E +++ Sbjct: 49 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGE-EVAVFDLPQIES 107 Query: 152 LIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 +D IL +D DR+G I+ SEF V S K+ Sbjct: 108 EVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKL 145 >2K7C-A nrPDB Length = 72 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AFR FD + DG ++ +L + L G R I+ I+ + D++ DG Sbjct: 8 ELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRD--------IEEIIRDVDLNGDG 59 Query: 167 TINLSEFQHVISR 179 ++ EF ++SR Sbjct: 60 RVDFEEFVRMMSR 72 Score = 29.3 bits (64), Expect = 1.00, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 21/59 (35%), Gaps = 1/59 (1%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 R F T+ +S + + + R D + DG ++ E+ R++ Sbjct: 13 FREFDTN-GDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMM 70 Score = 27.0 bits (58), Expect = 5.6, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 15/29 (51%) Query: 151 QLIDNILEESDIDRDGTINLSEFQHVISR 179 + + + E D + DG I+ SE + + + Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRK 35 >5COC-A nrPDB Length = 130 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 10/133 (7%) Query: 48 SLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIK 107 + Q F +IL LP L I + P++ + + L + + Sbjct: 6 NKEQQNAFYEILHLPNLNEEQRNAFIQSLKD-DPSQSANLLAEAKCLNDAQAAAEECIAE 64 Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D +GT Sbjct: 65 FKEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNGT 115 Query: 168 INLSEFQHVISRS 180 I+ EF +++R Sbjct: 116 IDFPEFLTMMARK 128 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 6/42 (14%), Positives = 18/42 (42%), Gaps = 2/42 (4%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSD 100 + L NP + + + + + ++ F +FL +++ Sbjct: 89 MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK 130 >5JOJ-A nrPDB Length = 97 Score = 53.6 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 7/96 (7%) Query: 95 LSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 ++ S + ++ AF D D +G ++ +L+ L L ++++ + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKA-----ACLPLPGYRVREITE 55 Query: 155 NILEESDIDRDGTINLSEFQHVI--SRSPDFASSFK 188 N++ D+D+DG I+ EF + +S D A +F+ Sbjct: 56 NLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFR 91 >5H7D-E nrPDB Length = 120 Score = 53.2 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 9/71 (12%) Query: 109 HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D +GTI Sbjct: 59 KEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNGTI 109 Query: 169 NLSEFQHVISR 179 + EF +++R Sbjct: 110 DFPEFLTMMAR 120 >5JOL-A nrPDB Length = 82 Score = 52.8 bits (125), Expect = 8e-08, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 95 LSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 ++ S + ++ AF D D +G ++ +L+ L L ++++ + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKA-----ACLPLPGYRVREITE 55 Query: 155 NILEESDIDRDGTINLSEFQHV 176 N++ D+D+DG I+ EF + Sbjct: 56 NLMATGDLDQDGRISFDEFIKI 77 >2LC5-A nrPDB Length = 151 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 12/120 (10%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD 118 + L ANP K++I + E FL ++ + AF IFD + Sbjct: 40 MRALGANPTKQKISEIVKDYDKDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKE 99 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 +G ++ +L ++ L +L+ E+ L+ I E +G IN+ +F +I+ Sbjct: 100 KNGYISASELKHVLTTL-----GEKLTEQEVDDLLKEIGVE-----EGLINVDDFVKLIT 149 >2AMI-A nrPDB Length = 96 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 9/80 (11%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 T + AF +FD D GT++ ++L + L E + K+ I ++ E Sbjct: 25 TEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPK---------KEEIKKMISEI 75 Query: 161 DIDRDGTINLSEFQHVISRS 180 D D GTI+ EF +++ Sbjct: 76 DKDGSGTIDFEEFLTMMTAK 95 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 36/101 (35%), Gaps = 9/101 (8%) Query: 1 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS 60 M + + + LT+++ F ++++ E ++ Sbjct: 3 MSYKAKTVVSARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAK-------ELKVA 55 Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFS 99 + L P KE I ++ S ++ FE+FL +++ Sbjct: 56 MRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKM 96 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 7/63 (11%), Positives = 19/63 (30%), Gaps = 2/63 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F T ++ ++ + + D D GT++ E+ + Sbjct: 34 EAFDLFDT-DGSGTIDAKELKVAMRAL-GFEPKKEEIKKMISEIDKDGSGTIDFEEFLTM 91 Query: 132 VNC 134 + Sbjct: 92 MTA 94 >2Q4U-A nrPDB Length = 272 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 26/178 (14%), Positives = 70/178 (39%), Gaps = 15/178 (8%) Query: 15 EYQDLTFLTKQEILLAHRRFCELL-PQEQRSVESSLRAQVPFEQILSLPELKANPFKERI 73 + D ++ +E+ R + L P+++ + E + + F E + Sbjct: 21 DADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATF-DGRLQIEEL 79 Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYA--FRIFDFDDDGTLNREDLSRL 131 + L +F A D + +R +D D G ++ +L Sbjct: 80 ANMILPQEEN----------FLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNF 129 Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 189 + L + + ++ +++ + D +++ D ++DG ++L++ +++ +F FK+ Sbjct: 130 LKDLFLQHKK-KIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKM 186 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 35/76 (46%), Gaps = 2/76 (2%) Query: 115 FDFDDDGTLNREDLSRLVNCLTGE-GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 FD DD+G + ++L + + +++ ++Q+ + + D DG + + E Sbjct: 20 FDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEEL 79 Query: 174 QHVIS-RSPDFASSFK 188 ++I + +F F+ Sbjct: 80 ANMILPQEENFLLIFR 95 >3IFK-A nrPDB Length = 90 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 34/94 (36%), Gaps = 9/94 (9%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 4 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTV-------MRSLGQNPTEAELQDMINEVD 56 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFR 113 + ++ F +FL +++ + + AFR Sbjct: 57 ADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D +G Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 61 Query: 167 TINLSEFQHVISRS 180 TI+ EF +++R Sbjct: 62 TIDFPEFLTMMARK 75 Score = 26.2 bits (56), Expect = 9.0, Method: Composition-based stats. Identities = 6/87 (6%), Positives = 28/87 (32%), Gaps = 10/87 (11%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F +++ ++ ++ + + D D +GT++ + + Sbjct: 14 EAFSLFD-KDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 71 Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILE 158 + ++ ++ ++ I Sbjct: 72 M--------ARKMKDTDSEEEIREAFR 90 >3J04-B nrPDB Length = 143 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 57/157 (36%), Gaps = 18/157 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 + +I F + ++ + L + NP E + + S +P Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM-------LASMGKNPTDEYLEGMMSEAP 53 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 ++F FL + + P+ AF FD + G ++ + L L+ + Sbjct: 54 --GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTM-----G 106 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 R + E +D + E+ ID+ G N EF ++ Sbjct: 107 DRFTDEE----VDEMYREAPIDKKGNFNYVEFTRILK 139 >2JNX-A nrPDB Length = 134 Score = 50.9 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 46/131 (35%), Gaps = 17/131 (12%) Query: 47 SSLRAQVPFEQILSL-PELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPD 105 + + +S +K + I + + +F + + D Sbjct: 14 DGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDI-DGNGEIDLAEFTKFAAAVKEQDLSD 72 Query: 106 IK--SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 K +++ D D DG L +E+++ ++++D I+ ++D + Sbjct: 73 EKVGLKILYKLMDADGDGKLTKEEVTTFFKKFG------------YEKVVDQIM-KADAN 119 Query: 164 RDGTINLSEFQ 174 DG I L EF Sbjct: 120 GDGYITLEEFL 130 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 17/110 (15%), Positives = 41/110 (37%), Gaps = 8/110 (7%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E + + + S+S+E+ +S + F+ D D +G ++ + + Sbjct: 2 AEALFKQLDAN-GDGSVSYEEVKAFVSSKRPIKN-EQLLQLIFKAIDIDGNGEIDLAEFT 59 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + + ++ LS ++ I + + D D DG + E + Sbjct: 60 KFAAAV----KEQDLSDEKVGLKI--LYKLMDADGDGKLTKEEVTTFFKK 103 Score = 27.8 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 5/27 (18%), Positives = 16/27 (59%) Query: 152 LIDNILEESDIDRDGTINLSEFQHVIS 178 + + + ++ D + DG+++ E + +S Sbjct: 1 MAEALFKQLDANGDGSVSYEEVKAFVS 27 >2K2A-A nrPDB Length = 70 Score = 50.5 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 36/74 (48%), Gaps = 9/74 (12%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDR 164 + AFR++D + +G ++ + + ++ L + + +D +++E D D Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREIL---------AELDETLSSEDLDAMIDEIDADG 52 Query: 165 DGTINLSEFQHVIS 178 GT++ EF V++ Sbjct: 53 SGTVDFEEFMGVMT 66 >1YX7-A nrPDB Length = 83 Score = 50.5 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 31/73 (42%), Gaps = 3/73 (4%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDI 162 + AF+ D + DG + +L + LS ++K+ +++ +D Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTF---MVTLDAYKALSKDKVKEASAKLIKMADK 60 Query: 163 DRDGTINLSEFQH 175 + DG I+ EF + Sbjct: 61 NSDGKISKEEFLN 73 Score = 26.2 bits (56), Expect = 8.5, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 27/76 (35%), Gaps = 7/76 (9%) Query: 68 PFKERICRVFSTSPAKD-----SLSFEDFLDLLSVFSDTATPDIKSHYA--FRIFDFDDD 120 K + F A +L + F+ L + + +K A ++ D + D Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD 63 Query: 121 GTLNREDLSRLVNCLT 136 G +++E+ L Sbjct: 64 GKISKEEFLNANAELL 79 >2BL0-C nrPDB Length = 142 Score = 50.5 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 36/105 (34%), Gaps = 12/105 (11%) Query: 75 RVFSTSP--AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 +F+ + + F +FL ++ T + AFR FD + G + + L + Sbjct: 46 EMFNEADATGNGKIQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDAL 105 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 L RL E + + E G I F + + Sbjct: 106 LNL-----GDRLKPHEFAEFLGITETEK-----GQIRYDNFINTM 140 Score = 39.7 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 28/73 (38%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD + G + +E L ++ E + + E+D +G Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAF---------NEMFNEADATGNG 57 Query: 167 TINLSEFQHVISR 179 I EF ++ R Sbjct: 58 KIQFPEFLSMMGR 70 >1JFJ-A nrPDB Length = 134 Score = 50.1 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 21/134 (15%), Positives = 41/134 (30%), Gaps = 17/134 (12%) Query: 47 SSLRAQVPFEQILSL-PELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPD 105 + + +S +K + I + + +F D Sbjct: 14 DGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDA-DGNGEIDQNEFAKFYGSIQGQDLSD 72 Query: 106 IK--SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 K +++ D D DG L +E+ V + +++ M ++D + Sbjct: 73 DKIGLKVLYKLMDVDGDGKLTKEE----VTSFFKKHGIEKVAEQVM---------KADAN 119 Query: 164 RDGTINLSEFQHVI 177 DG I L EF Sbjct: 120 GDGYITLEEFLEFS 133 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 15/111 (13%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E + + + ++S+E+ + + F+ D D +G +++ + + Sbjct: 2 AEALFKEIDVN-GDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFA 59 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 + + G+ LS ++ + + + D+D DG + E + Sbjct: 60 KFYGSIQGQ----DLSDDKIGLKV--LYKLMDVDGDGKLTKEEVTSFFKKH 104 Score = 30.4 bits (67), Expect = 0.50, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 18/34 (52%) Query: 152 LIDNILEESDIDRDGTINLSEFQHVISRSPDFAS 185 + + + +E D++ DG ++ E + +S+ + Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN 34 >1JC2-A nrPDB Length = 76 Score = 50.1 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 38/78 (48%), Gaps = 9/78 (11%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 + + FRIFD + DG ++ E+L ++ +++ I++++++S Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRAT---------GEHVIEEDIEDLMKDS 55 Query: 161 DIDRDGTINLSEFQHVIS 178 D + DG I+ EF ++ Sbjct: 56 DKNNDGRIDFDEFLKMME 73 >2I08-A nrPDB Length = 78 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF ++D D DGT+ ++L ++ L + +E++ +I+ E D D +G Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSL-----GLNPTEAELQDMIN----EVDADGNG 61 Query: 167 TINLSEFQHVISR 179 TI+ EF +++R Sbjct: 62 TIDFPEFLTMMAR 74 Score = 39.7 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 11/81 (13%), Positives = 29/81 (35%), Gaps = 9/81 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT+++I F ++ + V + L NP + + + + Sbjct: 4 LTEEQIAEFKEAFSLYDKDGDGTITTKELGTV-------MRSLGLNPTEAELQDMINEVD 56 Query: 80 SPAKDSLSFEDFLDLLSVFSD 100 + ++ F +FL +++ Sbjct: 57 ADGNGTIDFPEFLTMMARIMK 77 >4WPX-A nrPDB Length = 177 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 34/78 (43%), Gaps = 9/78 (11%) Query: 100 DTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEE 159 P + AFR+FD D G + +DL ++ + + ++++ +I+ Sbjct: 105 RQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQV-----GNNIPDADIQAMIEEF--- 156 Query: 160 SDIDRDGTINLSEFQHVI 177 D + G ++ EF ++ Sbjct: 157 -DSNGKGGVDEDEFLRLM 173 Score = 34.3 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 ++ + + +LS + K I E D ++DG ++ EF+ V+ Sbjct: 5 RQIQYTIPPREDYNKLSDEQ-KTRISEAFELFDSNKDGLLSYEEFRFVL 52 Score = 31.2 bits (69), Expect = 0.30, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 + AF +FD + DG L+ E+ ++ L Sbjct: 23 EQKTRISEAFELFDSNKDGLLSYEEFRFVLRAL 55 >5PAL-A nrPDB Length = 109 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 9/111 (8%) Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 + I + S + ++ F L+ + D + F I D D G + E+L Sbjct: 7 KADDINKAISAFKDPGTFDYKRFFHLVGLK---GKTDAQVKEVFEILDKDQSGFIEEEEL 63 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 ++ + G D + + +L D D DG I EF ++++ Sbjct: 64 KGVLKGFSAHGRDLNDTET------KALLAAGDSDHDGKIGADEFAKMVAQ 108 >4Q57-A nrPDB Length = 65 Score = 49.3 bits (116), Expect = 9e-07, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 9/71 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DGT+ ++L ++ L + +E++ +I+ E D D +G Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 53 Query: 167 TINLSEFQHVI 177 TI+ EF ++ Sbjct: 54 TIDFPEFLTMM 64 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 6/38 (15%), Positives = 18/38 (47%), Gaps = 2/38 (5%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLS 96 + L NP + + + + + ++ F +FL +++ Sbjct: 28 MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 65 Score = 27.4 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 5/61 (8%), Positives = 21/61 (34%), Gaps = 2/61 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F +++ ++ ++ + + D D +GT++ + + Sbjct: 6 EAFSLFD-KDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 63 Query: 132 V 132 + Sbjct: 64 M 64 >2RO8-A nrPDB Length = 79 Score = 49.3 bits (116), Expect = 9e-07, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D DG + ++L ++ L + +E++ +I+ E D D +G Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSL-----GQNPTEAELQDMIN----EVDADGNG 61 Query: 167 TINLSEFQHVISRS 180 TI+ EF ++++R Sbjct: 62 TIDFPEFLNLMARK 75 Score = 40.1 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 28/83 (33%), Gaps = 9/83 (10%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST-- 79 LT ++I F + + V + L NP + + + + Sbjct: 4 LTDEQISEFKEAFSLFDKDGDGCITTKELGTV-------MRSLGQNPTEAELQDMINEVD 56 Query: 80 SPAKDSLSFEDFLDLLSVFSDTA 102 + ++ F +FL+L++ Sbjct: 57 ADGNGTIDFPEFLNLMARKMKDT 79 >2KSZ-A nrPDB Length = 76 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Query: 109 HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 AF +FD D DG + E+L+ ++ L D + E++ +I E D D +GTI Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSL-----DQNPTEEELQDMI----SEVDADGNGTI 63 Query: 169 NLSEFQHVISRS 180 EF ++++ Sbjct: 64 EFDEFLSLMAKK 75 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVF 98 + L NP +E + + S + ++ F++FL L++ Sbjct: 36 IRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMAKK 75 Score = 27.8 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 8/61 (13%), Positives = 21/61 (34%), Gaps = 2/61 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F ++ E+ ++ D + + D D +GT+ ++ L Sbjct: 14 EAFGLFD-KDGDGCITVEELATVI-RSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSL 71 Query: 132 V 132 + Sbjct: 72 M 72 >1GGW-A nrPDB Length = 140 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 16/123 (13%) Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSV---FSDTATPDIKSHYAFRIFDF 117 L NP I + ST PA+ + E FL +L+ F P+ F++FD Sbjct: 31 LRACGQNPTLAEITEIESTLPAE--VDMEQFLQVLNRPNGFDMPGDPEEFVK-GFQVFDK 87 Query: 118 DDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 D G + +L ++ L +LS EM +L+ + + DG +N +F +I Sbjct: 88 DATGMIGVGELRYVLTSL-----GEKLSNEEMDELLKGVPVK-----DGMVNYHDFVQMI 137 Query: 178 SRS 180 + Sbjct: 138 LAN 140 Score = 26.2 bits (56), Expect = 9.6, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 21/58 (36%) Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEE 159 +T D AF +FD G + + + L+ ++ E + +E+ Sbjct: 1 STDDSPYKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEITEIESTLPAEVDMEQ 58 >1SR6-C nrPDB Length = 156 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 64 LKANPFKERICRVFST-SPAKDSLSFEDFLDLLSVFSD-TATPDIKSHYAFRIFDFDDDG 121 L NP E + V T + SL FE+FL D AF+ FD + G Sbjct: 40 LGINPRNEDVFAVGGTHKMGEKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQG 99 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 ++ +L ++ L RLS ++ ++I + D+ +G + +F + P Sbjct: 100 FISGAELRHVLTAL-----GERLSDEDVDEIIKLTDLQEDL--EGNVKYEDFVKKVMAGP 152 >5ZGM-A nrPDB Length = 110 Score = 48.2 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 45/111 (40%), Gaps = 9/111 (8%) Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 + I + S + ++ F L+ + + + F I D D G + E+L Sbjct: 8 KADDINKAVSAFKDPGTFDYKRFFQLVGLK---GKSEAQVKEVFEILDKDQSGFIEEEEL 64 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 ++ + G D LS +E K L L D D DG I EF ++++ Sbjct: 65 KSVLKGFSAHGRD--LSDTETKAL----LAAGDSDHDGKIGADEFAKMVAQ 109 >2G9B-A nrPDB Length = 263 Score = 48.2 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 + +R +D D G + E+L + L E + + +++ + D +L+ D + D Sbjct: 103 EEFMKTWRKYDTDHSGFIETEELKNFLKDLL-EKANKTVDDTKLAEYTDLMLKLFDSNND 161 Query: 166 GTINLSEFQHVISRSPDFASSFKIV 190 G + L+E ++ +F F+ + Sbjct: 162 GKLELTEMARLLPVQENFLLKFQGI 186 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 33/81 (40%), Gaps = 8/81 (9%) Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSV-------FSDTATPDIKSHYAFRIFDFDDDG 121 + + + ++F ++ L + LL V F + + AF ++D D +G Sbjct: 148 YTDLMLKLFDSN-NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 206 Query: 122 TLNREDLSRLVNCLTGEGEDT 142 ++ +L L+ L + + Sbjct: 207 YIDENELDALLKDLCEKNKQE 227 Score = 32.8 bits (73), Expect = 0.089, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 3/74 (4%) Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD D G L ++L L+ L + L E+ + +++ DG I + E Sbjct: 25 FDADGSGYLEGKELQNLIQELLQARKKAGL---ELSPEMKTFVDQYGQRDDGKIGIVELA 81 Query: 175 HVISRSPDFASSFK 188 HV+ +F F+ Sbjct: 82 HVLPTEENFLLLFR 95 >2M97-A nrPDB Length = 69 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 9/76 (11%) Query: 104 PDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 + + FRIFD D +G ++RE+ ++ +L+ + +D I +SD D Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRL-----TGEQLTDED----VDEIFGDSDTD 51 Query: 164 RDGTINLSEFQHVISR 179 ++G I+ EF ++ Sbjct: 52 KNGRIDFDEFLKMMEN 67 Score = 29.3 bits (64), Expect = 0.99, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 R+F + E+F D++ + D F D D +G ++ ++ ++ Sbjct: 7 ECFRIFD-KDGNGFIDREEFGDII-RLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKM 64 Query: 132 VNCLT 136 + + Sbjct: 65 MENVQ 69 >5OTJ-D nrPDB Length = 110 Score = 47.4 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 10/73 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ FD + DG ++ +L+ + L D + ++ E D D DG I+ + Sbjct: 9 FKRFDTNGDGKISLSELTDALRTLGSTSADE----------VQRMMAEIDTDGDGFIDFN 58 Query: 172 EFQHVISRSPDFA 184 EF + +P Sbjct: 59 EFISFCNANPGLM 71 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 15/29 (51%) Query: 149 MKQLIDNILEESDIDRDGTINLSEFQHVI 177 M ++ I + D + DG I+LSE + Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDAL 29 >3PAT-A nrPDB Length = 110 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 46/109 (42%), Gaps = 9/109 (8%) Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 128 + I + A+ S + + F L+ + + +A K F+ D D G + E+L Sbjct: 8 KADDIKKALDAVKAEGSFNHKKFFALVGLKAMSANDVKKV---FKAIDADASGFIEEEEL 64 Query: 129 SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 ++ +G D + + L+ +D D DG I + EF+ ++ Sbjct: 65 KFVLKSFAADGRDLTDAET------KAFLKAADKDGDGKIGIDEFETLV 107 Score = 28.1 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 32/90 (35%), Gaps = 4/90 (4%) Query: 47 SSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTA-TPD 105 F ++ L + AN K ++ + A + E+ +L F+ Sbjct: 22 EGSFNHKKFFALVGLKAMSANDVK-KVFKAIDA-DASGFIEEEELKFVLKSFAADGRDLT 79 Query: 106 IKSHYAF-RIFDFDDDGTLNREDLSRLVNC 134 AF + D D DG + ++ LV+ Sbjct: 80 DAETKAFLKAADKDGDGKIGIDEFETLVHE 109 >1OZS-A nrPDB Length = 73 Score = 47.0 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 34/78 (43%), Gaps = 9/78 (11%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 + + FR+FD + DG ++ E+L ++ + + I+ ++++ Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT---------GETITEDDIEELMKDG 52 Query: 161 DIDRDGTINLSEFQHVIS 178 D + DG I+ EF + Sbjct: 53 DKNNDGRIDYDEFLEFMK 70 Score = 27.0 bits (58), Expect = 5.8, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 28/70 (40%), Gaps = 2/70 (2%) Query: 64 LKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTL 123 K+ + R+F + A + E+ +L +T T D + D ++DG + Sbjct: 3 GKSEEELSDLFRMFDKN-ADGYIDLEELKIMLQATGETITEDD-IEELMKDGDKNNDGRI 60 Query: 124 NREDLSRLVN 133 + ++ + Sbjct: 61 DYDEFLEFMK 70 >2BL0-B nrPDB Length = 145 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 46/124 (37%), Gaps = 21/124 (16%) Query: 60 SLPELKANPFKERICRVFSTSPAKDSLSFEDF----LDLLSVFSDTATPDI--KSHYAFR 113 +L L NP + + K L+ ++F + + + AFR Sbjct: 30 ALRSLGKNPTNAEL------NTIKGQLNAKEFDLATFKTVYRKPIKTPTEQSKEMLDAFR 83 Query: 114 IFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 D + +GT+ +L +L+ L + ++ +++E + DG IN F Sbjct: 84 ALDKEGNGTIQEAELRQLL---------LNLGDALTSSEVEELMKEVSVSGDGAINYESF 134 Query: 174 QHVI 177 ++ Sbjct: 135 VDML 138 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 39/108 (36%), Gaps = 28/108 (25%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRL--------------------- 144 + F+IFD D+DG ++ E+L + L + L Sbjct: 5 DQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATFKTVY 64 Query: 145 ------SASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 + K+++D D + +GTI +E + ++ D +S Sbjct: 65 RKPIKTPTEQSKEMLD-AFRALDKEGNGTIQEAELRQLLLNLGDALTS 111 >5E1J-A nrPDB Length = 741 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 6/97 (6%) Query: 85 SLSFEDFLDLLSVFSDTAT--PDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDT 142 ++ ++ F + L+ AF + D D +G +++ +L LT Sbjct: 302 AVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLP 361 Query: 143 RLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 ++S E I +E D RD IN EF + Sbjct: 362 KISKEEFG----LIFDELDDTRDFKINKDEFADLCQA 394 >3AAJ-A nrPDB Length = 167 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 41/116 (35%), Gaps = 19/116 (16%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 I +F K ++F +F + +D FR +D D+ G +++ +L + + Sbjct: 46 IISMFD-RENKAGVNFSEFTGVWKYITDWQNV-------FRTYDRDNSGMIDKNELKQAL 97 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 RLS Q D ++ + D G I +F F+ Sbjct: 98 -------SGYRLSD----QFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFR 142 Score = 35.5 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 10/70 (14%) Query: 69 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTL--NRE 126 F + + R F + ++F+DF+ V FR +D D DG + + E Sbjct: 106 FHDILIRKFD-RQGRGQIAFDDFIQGCIVLQRLTDI-------FRRYDTDQDGWIQVSYE 157 Query: 127 DLSRLVNCLT 136 +V + Sbjct: 158 QYLSMVFSIV 167 >4ZCV-A nrPDB Length = 165 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 +E+I + L FE+F+ L + K AF+ D ++DG + ++ Sbjct: 51 EEKIFTTGDVN-KDGKLDFEEFMKYL------KDHEKKMKLAFKSLDKNNDGKIEASEIV 103 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 + + L + +Q + IL+ D+D T++ +E++ +P Sbjct: 104 QSLQ---------TLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNP 146 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 26/70 (37%), Gaps = 9/70 (12%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ D + DG ++ +L + L + + I D+++DG ++ Sbjct: 19 FQALDRNGDGVVDIGELQEGLRNLGIPLG---------QDAEEKIFTTGDVNKDGKLDFE 69 Query: 172 EFQHVISRSP 181 EF + Sbjct: 70 EFMKYLKDHE 79 >4N5X-A nrPDB Length = 199 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 +E+I + L FE+F+ L + K AF+ D ++DG + ++ Sbjct: 60 EEKIFTTGDVN-KDGKLDFEEFMKYL------KDHEKKMKLAFKSLDKNNDGKIEASEIV 112 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 + + L + +Q + IL+ D+D T++ +E++ +P Sbjct: 113 QSLQ---------TLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNP 155 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 30/86 (34%), Gaps = 9/86 (10%) Query: 96 SVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDN 155 + S A + F+ D + DG ++ +L + L + + Sbjct: 12 TAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLG---------QDAEEK 62 Query: 156 ILEESDIDRDGTINLSEFQHVISRSP 181 I D+++DG ++ EF + Sbjct: 63 IFTTGDVNKDGKLDFEEFMKYLKDHE 88 >1C7W-A nrPDB Length = 81 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 43/84 (51%), Gaps = 8/84 (9%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 + + AF++FD + DG ++ ++ ++ + + L+ +E ++ ++E+ Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKV----GEEPLTDAE----VEEAMKEA 54 Query: 161 DIDRDGTINLSEFQHVISRSPDFA 184 D D +G I++ EF +I +S + Sbjct: 55 DEDGNGVIDIPEFMDLIKKSKNAL 78 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 26/62 (41%), Gaps = 1/62 (1%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 R +VF + + F++F ++ + D + A + D D +G ++ + L Sbjct: 12 RAFKVFDAN-GDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEFMDL 70 Query: 132 VN 133 + Sbjct: 71 IK 72 >1W7I-B nrPDB Length = 151 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 44/121 (36%), Gaps = 16/121 (13%) Query: 61 LPELKANPFKERICRVF----STSPAKDSLSFEDFLDLLSV--FSDTATPDIKSHYAFRI 114 + L NP + +V S + FE FL +L + FR+ Sbjct: 36 MRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRV 95 Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD + +G + +L ++ L +++ E++ ++ D +G IN F Sbjct: 96 FDKEGNGKVMGAELRHVLTTL-----GEKMTEEEVETVLAGH-----EDSNGCINYEAFL 145 Query: 175 H 175 Sbjct: 146 K 146 Score = 29.7 bits (65), Expect = 0.89, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 29/74 (39%), Gaps = 7/74 (9%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 + AF +FD DG + ++ L + +E+ +++ N +SD + Sbjct: 10 EEFKEAFELFDRVGDGKILYSQCGDVMRAL-----GQNPTNAEVLKVLGNP--KSDELKS 62 Query: 166 GTINLSEFQHVISR 179 ++ F ++ Sbjct: 63 RRVDFETFLPMLQA 76 >2M8U-A nrPDB Length = 77 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 9/68 (13%) Query: 110 YAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTIN 169 AF++FD D +G + + L +++N L I+ ++ E+D G + Sbjct: 15 EAFKVFDRDGNGYVTVDYLRKVLN---------ELGDMMPADEIEEMIYEADPQNSGYVQ 65 Query: 170 LSEFQHVI 177 F ++ Sbjct: 66 YETFVGML 73 >3JAX-C nrPDB Length = 151 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 25/163 (15%), Positives = 54/163 (33%), Gaps = 23/163 (14%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVF--- 77 ++++ F + + L NP + +V Sbjct: 3 DFSEEQTAEFKEAFQLFDRTG-----DGKILYSQCGDV--MRALGQNPTNAEVMKVLGNP 55 Query: 78 -STSPAKDSLSFEDFLDLLSVFSDTATPD--IKSHYAFRIFDFDDDGTLNREDLSRLVNC 134 S +L FE FL ++ + R+FD + +GT+ ++ ++ Sbjct: 56 KSDEMNLKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVT 115 Query: 135 LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 L +++ E++QL+ D +G IN E ++ Sbjct: 116 L-----GEKMTEEEVEQLVAGH-----EDSNGCINYEELVRMV 148 Score = 30.8 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 35/84 (41%), Gaps = 9/84 (10%) Query: 95 LSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 + FS+ T + K AF++FD DG + ++ L + A MK L + Sbjct: 1 MCDFSEEQTAEFK--EAFQLFDRTGDGKILYSQCGDVMRALGQNPTN----AEVMKVLGN 54 Query: 155 NILEESDIDRDGTINLSEFQHVIS 178 +E ++ T+ +F ++ Sbjct: 55 PKSDEMNLK---TLKFEQFLPMMQ 75 >2LVK-A nrPDB Length = 77 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 10/73 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ FD + DG ++ +L+ + L D + ++ E D D DG I+ + Sbjct: 8 FKRFDTNGDGKISLSELTDALRTLGSTSADE----------VQRMMAEIDTDGDGFIDFN 57 Query: 172 EFQHVISRSPDFA 184 EF + +P Sbjct: 58 EFISFCNANPGLM 70 Score = 26.6 bits (57), Expect = 6.0, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 153 IDNILEESDIDRDGTINLSEFQHVI 177 ++ I + D + DG I+LSE + Sbjct: 4 MERIFKRFDTNGDGKISLSELTDAL 28 >3E3R-A nrPDB Length = 204 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 55/151 (36%), Gaps = 11/151 (7%) Query: 27 ILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSL 86 I R F +L RS++ A + + L + E +CR + + +L Sbjct: 36 IQGLARFFRQLDRDGSRSLD----ADEFRQGLAKLGLVLDQAEAEGVCRKWDRN-GSGTL 90 Query: 87 SFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV--NCLTGEGEDTRL 144 E+FL L A + AF D DG + +DL + Sbjct: 91 DLEEFLRALRPPMSQAR-EAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWT 149 Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQH 175 +++ +DN ++DG + L+EFQ Sbjct: 150 EDEVLRRFLDNFDS---SEKDGQVTLAEFQD 177 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 28/66 (42%), Gaps = 9/66 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D D +L+ ++ + + L L +E + + + D + GT++L Sbjct: 43 FRQLDRDGSRSLDADEFRQGLAKL-----GLVLDQAE----AEGVCRKWDRNGSGTLDLE 93 Query: 172 EFQHVI 177 EF + Sbjct: 94 EFLRAL 99 Score = 27.0 bits (58), Expect = 5.0, Method: Composition-based stats. Identities = 4/25 (16%), Positives = 12/25 (48%) Query: 155 NILEESDIDRDGTINLSEFQHVISR 179 + D D +++ EF+ +++ Sbjct: 41 RFFRQLDRDGSRSLDADEFRQGLAK 65 >3LCP-C nrPDB Length = 93 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNIL 157 + +++ HY F++ D+D + L+ +LS + + E + +S E+ +ID +L Sbjct: 14 MSPQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVL 72 Query: 158 EESDIDRDGTINLSEFQHVIS 178 + D + DG I+ +EF + Sbjct: 73 RDDDKNNDGYIDYAEFAKSLQ 93 >2VRG-A nrPDB Length = 124 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNIL 157 + +++ HY F++ D+D + L+ +LS + + E + +S E+ +ID +L Sbjct: 45 MSPQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVL 103 Query: 158 EESDIDRDGTINLSEFQHVIS 178 + D + DG I+ +EF + Sbjct: 104 RDDDKNNDGYIDYAEFAKSLQ 124 >1ZMZ-A nrPDB Length = 98 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 36/80 (45%), Gaps = 9/80 (11%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 T + AF +FD D GT++ ++L + L E + K+ I ++ E Sbjct: 26 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPK---------KEEIKKMISEI 76 Query: 161 DIDRDGTINLSEFQHVISRS 180 D + G +N +F V+++ Sbjct: 77 DKEGTGKMNFGDFLTVMTQK 96 Score = 35.8 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 32/99 (32%), Gaps = 9/99 (9%) Query: 3 GSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLP 62 + S LT+++ F +++ E +++ Sbjct: 6 KKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVK-------ELKVAMR 58 Query: 63 ELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFS 99 L P KE I ++ S ++F DFL +++ Sbjct: 59 ALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKM 97 >5XND-A nrPDB Length = 114 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 36/108 (33%), Gaps = 9/108 (8%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 + A S + F + + AF I D D G + E+L Sbjct: 15 AEVTAALDGCKAAGSFDHKKFFKACG---LSGKSTDEVKKAFAIIDQDKSGFIEEEELKL 71 Query: 131 LVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + + LS +E K L+ D D DG I + EF +I Sbjct: 72 FLQNF--KAGARALSDAETKA----FLKAGDSDGDGKIGIDEFAAMIK 113 >5TBY-C nrPDB Length = 195 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 54/161 (33%), Gaps = 21/161 (13%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVF--- 77 T ++I F + + + L L NP + + RV Sbjct: 45 EFTPEQIEEFKEAFMLFDRTPKCEM---KITYGQCGDV--LRALGQNPTQAEVLRVLGKP 99 Query: 78 -STSPAKDSLSFEDFLDLLSVFSDTATP--DIKSHYAFRIFDFDDDGTLNREDLSRLVNC 134 + FE FL +L S R+FD + +GT+ +L ++ Sbjct: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 Query: 135 LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 L RL+ E+++L + + D + G IN F Sbjct: 160 L-----GERLTEDEVEKL---MAGQEDSN--GCINYEAFVK 190 >3A4U-B nrPDB Length = 143 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDNIL 157 + +++ HY F++ D+D + L+ +LS + + E + +S E+ +ID +L Sbjct: 64 MSPQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVL 122 Query: 158 EESDIDRDGTINLSEFQHVIS 178 + D + DG I+ +EF + Sbjct: 123 RDDDKNNDGYIDYAEFAKSLQ 143 >6FSA-D nrPDB Length = 199 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 46/121 (38%), Gaps = 16/121 (13%) Query: 61 LPELKANPFKERICRVF----STSPAKDSLSFEDFLDLLSVFSDTATP--DIKSHYAFRI 114 L L NP + + RV + F+ FL +L S R+ Sbjct: 84 LRALGQNPTQAEVLRVLGKPKQEELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRV 143 Query: 115 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 FD + +GT+ +L ++ L +L+ E+++L + + D + G IN F Sbjct: 144 FDKEGNGTVMGAELRHVLATL-----GEKLTEDEVEKL---MAGQEDSN--GCINYEAFV 193 Query: 175 H 175 Sbjct: 194 K 194 >4YGB-B nrPDB Length = 104 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR---LSASEMKQLIDN 155 +P + F++ D+D + L+ +LS + + E + +S E+ +ID Sbjct: 22 MLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 81 Query: 156 ILEESDIDRDGTINLSEFQHVIS 178 +L + D + DG I+ +EF + Sbjct: 82 VLRDDDKNNDGYIDYAEFAKSLQ 104 >2NCO-A nrPDB Length = 102 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Query: 103 TPDIKSHYA---FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEE 159 + K A F+ +D D G L ++++ L+ E + + + K+ + L+ Sbjct: 9 EVEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPT--KEDVKIWLQM 66 Query: 160 SDIDRDGTINLSEFQHVISRS 180 +D + DG+++L E++ +I +S Sbjct: 67 ADTNSDGSVSLEEYEDLIIKS 87 >2OPO-A nrPDB Length = 86 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 27/69 (39%), Gaps = 10/69 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ FD + DG ++ +L + L S + ++ E D D DG I+ Sbjct: 17 FKRFDTNGDGKISSSELGDALKTL----------GSVTPDEVRRMMAEIDTDGDGFISFD 66 Query: 172 EFQHVISRS 180 EF + Sbjct: 67 EFTDFARAN 75 Score = 31.6 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 3/68 (4%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 ERI + F T+ +S + D L +++ A D D DG ++ ++ + Sbjct: 14 ERIFKRFDTN-GDGKISSSELGDALKTLGSVTPDEVRRMMA--EIDTDGDGFISFDEFTD 70 Query: 131 LVNCLTGE 138 G Sbjct: 71 FARANRGL 78 >1TRF-A nrPDB Length = 76 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D G ++ ++L ++ L K+ +D I+EE D D G Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPT---------KEELDAIIEEVDEDGSG 60 Query: 167 TINLSEFQHVISR 179 TI+ EF ++ R Sbjct: 61 TIDFEEFLVMMVR 73 Score = 31.6 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 17/42 (40%), Gaps = 2/42 (4%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSD 100 + L NP KE + + ++ FE+FL ++ Sbjct: 35 MRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMK 76 >1H4B-A nrPDB Length = 84 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 10/65 (15%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ FD + DG ++ +L + L D + +++ E D D DG I+ Sbjct: 15 FKRFDANGDGKISAAELGEALKTLGSITPDE----------VKHMMAEIDTDGDGFISFQ 64 Query: 172 EFQHV 176 EF Sbjct: 65 EFTDF 69 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 25/68 (36%), Gaps = 3/68 (4%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 ERI + F + +S + + L ++K A D D DG ++ ++ + Sbjct: 12 ERIFKRFDAN-GDGKISAAELGEALKTLGSITPDEVKHMMA--EIDTDGDGFISFQEFTD 68 Query: 131 LVNCLTGE 138 G Sbjct: 69 FGRANRGL 76 >1F55-A nrPDB Length = 77 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 38/73 (52%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D++G+++ +L+ ++ L + +++++ E D+D + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPS---------EAEVNDLMNEIDVDGNH 61 Query: 167 TINLSEFQHVISR 179 I SEF ++SR Sbjct: 62 QIEFSEFLALMSR 74 Score = 30.1 bits (66), Expect = 0.66, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 30/84 (35%), Gaps = 9/84 (10%) Query: 19 LTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFS 78 + LT+++I F S+ SS A V + L +P + + + + Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATV-------MRSLGLSPSEAEVNDLMN 53 Query: 79 T--SPAKDSLSFEDFLDLLSVFSD 100 + F +FL L+S Sbjct: 54 EIDVDGNHQIEFSEFLALMSRQLK 77 >1TNP-A nrPDB Length = 90 Score = 43.2 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 9/73 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + AF +FD D G ++ ++L ++ L K+ +D I+EE D D G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPT---------KEELDAIIEEVDEDGSG 71 Query: 167 TINLSEFQHVISR 179 TI+ EF ++ R Sbjct: 72 TIDFEEFLVMMVR 84 Score = 31.6 bits (70), Expect = 0.19, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 17/43 (39%), Gaps = 2/43 (4%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT 101 + L NP KE + + ++ FE+FL ++ Sbjct: 46 MRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKE 88 >2SAS-A nrPDB Length = 185 Score = 43.2 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 18/128 (14%), Positives = 40/128 (31%), Gaps = 14/128 (10%) Query: 66 ANPFKERICRVFSTSPAKDSLSFEDFLDLLSV--------------FSDTATPDIKSHYA 111 + F S+ DF D+++ S A+ + + Sbjct: 6 QKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDL 65 Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 D + D ++ E+ + + + + I + + D+ DG ++L Sbjct: 66 KGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIVDLE 125 Query: 172 EFQHVISR 179 EFQ+ Sbjct: 126 EFQNYCKN 133 Score = 35.5 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 104 PDIKSHYAFRIF-DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEE--- 159 K + F F D + DG++ D ++ E LS ++ K + ++ +E Sbjct: 6 QKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTR-YKEVNKGSLSDADYKSMQASLEDEWRD 64 Query: 160 ----SDIDRDGTINLSEFQHVISRS 180 +DI++D ++ E+ + ++ Sbjct: 65 LKGRADINKDDVVSWEEYLAMWEKT 89 >2KYF-A nrPDB Length = 108 Score = 43.2 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 6/72 (8%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + FRI D D G + ++L + E L+ASE K L +D D DG Sbjct: 42 QLKEIFRILDNDQSGFIEEDELKYFLQ--RFESGARVLTASETK----TFLAAADHDGDG 95 Query: 167 TINLSEFQHVIS 178 I EFQ ++ Sbjct: 96 KIGAEEFQEMVQ 107 >5H53-C nrPDB Length = 153 Score = 43.2 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 53/161 (32%), Gaps = 23/161 (14%) Query: 21 FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVF--- 77 +K++ F + S V L L NP + +V Sbjct: 4 EFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDV-------LRALGTNPTNAEVKKVLGNP 56 Query: 78 -STSPAKDSLSFEDFLDLLSVFSDTAT--PDIKSHYAFRIFDFDDDGTLNREDLSRLVNC 134 + + FE FL +L S+ R+FD + +GT+ +L ++ Sbjct: 57 SNEEMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 116 Query: 135 LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 L ++ E++ L + + D + G IN F Sbjct: 117 L-----GEKMKEEEVEAL---MAGQEDSN--GCINYEAFVK 147 Score = 28.9 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 8/87 (9%), Positives = 27/87 (31%), Gaps = 12/87 (13%) Query: 103 TPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL------------TGEGEDTRLSASEMK 150 + AF ++D D + + ++ L G + ++A +++ Sbjct: 8 EQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIE 67 Query: 151 QLIDNILEESDIDRDGTINLSEFQHVI 177 + ++ + +F + Sbjct: 68 FEQFLPMLQAISNNKDQGTYEDFVEGL 94 >2N7L-C nrPDB Length = 141 Score = 43.2 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 10/85 (11%) Query: 96 SVFSDTATPDIKSHYAFRIFDFD-DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 +V T + AF IF +DG+++ ++L +++ L + E++++ID Sbjct: 23 AVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-----GQNPTPEELQEMID 77 Query: 155 NILEESDIDRDGTINLSEFQHVISR 179 E D D GT++ EF ++ R Sbjct: 78 ----EVDEDGSGTVDFDEFLVMMVR 98 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 7/43 (16%), Positives = 16/43 (37%), Gaps = 2/43 (4%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT 101 + L NP E + + ++ F++FL ++ Sbjct: 60 MRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMKD 102 >2K7B-A nrPDB Length = 76 Score = 42.8 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 31/79 (39%), Gaps = 9/79 (11%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 S + AFR FD D DG +N DL + + + L + + Sbjct: 3 SLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIE---------LSQ 53 Query: 159 ESDIDRDGTINLSEFQHVI 177 + +++ G ++ +F ++ Sbjct: 54 QINMNLGGHVDFDDFVELM 72 >5VLN-A nrPDB Length = 120 Score = 42.8 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 10/86 (11%) Query: 96 SVFSDTATPDIKSHYAFRIFDFD-DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 +V T + AF IF +DG+++ ++L +++ L + E++++ID Sbjct: 8 AVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-----GQNPTPEELQEMID 62 Query: 155 NILEESDIDRDGTINLSEFQHVISRS 180 E D D GT++ EF ++ RS Sbjct: 63 ----EVDEDGSGTVDFDEFLVMMVRS 84 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 7/43 (16%), Positives = 16/43 (37%), Gaps = 2/43 (4%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT 101 + L NP E + + ++ F++FL ++ Sbjct: 45 MRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKD 87 >3I5H-B nrPDB Length = 153 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 39/122 (31%), Gaps = 9/122 (7%) Query: 14 AEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERI 73 E L+++++ F + + + S L P + + Sbjct: 2 EEAPRRVKLSQRQMQELKEAFTMIDQDR-----DGFIGMEDLKDMFS--SLGRVPPDDEL 54 Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 + P L+F FL L P+ AF +FD D G + + L L+ Sbjct: 55 NAMLKECP--GQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLE 112 Query: 134 CL 135 + Sbjct: 113 NM 114 >1I84-U nrPDB Length = 166 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 40/127 (31%), Gaps = 8/127 (6%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 + EI F + ++ E ++ L N E + + Sbjct: 19 FDETEIEDFKEAFTVIDQNADGIIDK----DDLRETFAAMGRL--NVKNEELDAMI--KE 70 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 A ++F FL + A P+ AF++ D D G++ + L L+ G Sbjct: 71 ASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTP 130 Query: 142 TRLSASE 148 + Sbjct: 131 EEIKNMW 137 Score = 30.8 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 20/58 (34%), Gaps = 4/58 (6%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNI 156 T AF + D + DG ++++DL + + E+ +I Sbjct: 18 MFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAM----GRLNVKNEELDAMIKEA 71 >1O1A-B nrPDB Length = 145 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 40/127 (31%), Gaps = 8/127 (6%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 + EI F + ++ E ++ L N E + + Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDK----DDLRETFAAMGRL--NVKNEELDAMI--KE 52 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 A ++F FL + A P+ AF++ D D G++ + L L+ G Sbjct: 53 ASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTP 112 Query: 142 TRLSASE 148 + Sbjct: 113 EEIKNMW 119 Score = 30.4 bits (67), Expect = 0.48, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 20/56 (35%), Gaps = 4/56 (7%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNI 156 T AF + D + DG ++++DL + + E+ +I Sbjct: 2 DETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAM----GRLNVKNEELDAMIKEA 53 >1Y1X-A nrPDB Length = 191 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 31/81 (38%), Gaps = 9/81 (11%) Query: 96 SVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDN 155 + + + + FR D D G ++ +L+ L+ G L+ +E Sbjct: 17 APSARHMNDNQELMEWFRAVDTDGSGAISVPELNA---ALSSAGVPFSLATTE------K 67 Query: 156 ILEESDIDRDGTINLSEFQHV 176 +L D + G I EF+ + Sbjct: 68 LLHMYDKNHSGEITFDEFKDL 88 Score = 35.5 bits (80), Expect = 0.016, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 36/110 (32%), Gaps = 23/110 (20%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLS---VFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 R T ++S + LS V AT + H ++D + G + ++ Sbjct: 33 FRAVDT-DGSGAISVPELNAALSSAGVPFSLATTEKLLH----MYDKNHSGEITFDEFKD 87 Query: 131 LVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 L + + E + D DG ++ +E + + S Sbjct: 88 LHHFILSMREG---------------FRKRDSSGDGRLDSNEVRAALLSS 122 >1RTP-1 nrPDB Length = 109 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 43/111 (38%), Gaps = 9/111 (8%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E I + A DS + F ++ + +A K F I D D G + ++L Sbjct: 8 AEDIKKAIGAFTAADSFDHKKFFQMVGLKKKSADDVKKV---FHILDKDKSGFIEEDELG 64 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 ++ + + D + ++ D D DG I + EF +++ S Sbjct: 65 SILKGFSSDARDLSAKET------KTLMAAGDKDGDGKIGVEEFSTLVAES 109 >4I5L-B nrPDB Length = 413 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 65/190 (34%), Gaps = 12/190 (6%) Query: 4 SGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPE 63 L +E Q F + + + + +F EL +++ A+ + Sbjct: 174 QNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHAL----- 228 Query: 64 LKANPFKERICRVFSTSPAK----DSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 + +RI T K +S+ DF+ L D TP Y FR D D Sbjct: 229 --STKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTP-TSIEYWFRCMDLDG 285 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 DG L+ +L + + A + + +L+ +G I L + + Sbjct: 286 DGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLA 345 Query: 180 SPDFASSFKI 189 + F + F I Sbjct: 346 NVFFDTFFNI 355 >4P5W-A nrPDB Length = 411 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 47/143 (32%), Gaps = 29/143 (20%) Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 E + NP + +SF++F+ SV PD AF++FD Sbjct: 70 FGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCA---PDALFMVAFQLFDKAGK 126 Query: 121 GTLNREDLSRL------------------VNCLTGEGEDTRLSASEMKQ--------LID 154 G + ED+ ++ V G+ L+ +E Q Sbjct: 127 GEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAK 186 Query: 155 NILEESDIDRDGTINLSEFQHVI 177 + D R G + +F+ ++ Sbjct: 187 QAFVQRDNARTGRVTAIDFRDIM 209 >5TBY-E nrPDB Length = 166 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 25/161 (15%), Positives = 55/161 (34%), Gaps = 17/161 (10%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 + +I F + ++ + + +L + N E I + Sbjct: 21 FEQTQIQEFKEAFTIMDQNRDGFIDKNDL----RDTFAAL--GRVNVKNEEIDEMI--KE 72 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 A ++F FL + A P+ AF++FD + G L + + ++ Sbjct: 73 APGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREML--------- 123 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 182 T + K+ +D + D G ++ H+I+ + Sbjct: 124 TTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEE 164 Score = 32.8 bits (73), Expect = 0.089, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 21/58 (36%), Gaps = 4/58 (6%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNI 156 T + AF I D + DG +++ DL L + E+ ++I Sbjct: 20 MFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAAL----GRVNVKNEEIDEMIKEA 73 >2KQY-A nrPDB Length = 108 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 40/110 (36%), Gaps = 9/110 (8%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 + I S+ A DS +++ F + + S T F I D D G + E+L Sbjct: 8 AKDIESALSSCQAADSFNYKSFFSTVGLSSKTPDQ---IKKVFGILDQDKSGFIEEEELQ 64 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + + + + L D D DG I + EFQ ++ Sbjct: 65 LFLKNFSSSARVLTSAET------KAFLAAGDTDGDGKIGVEEFQSLVKA 108 >5ZH6-A nrPDB Length = 107 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 6/79 (7%) Query: 101 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES 160 T D F I D D G + ++L + + + + + + L Sbjct: 35 TNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETET------NAFLAAG 88 Query: 161 DIDRDGTINLSEFQHVISR 179 D D DG I + EF+ ++ Sbjct: 89 DSDHDGKIGVDEFKAMVKA 107 Score = 26.6 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 25/72 (34%), Gaps = 4/72 (5%) Query: 67 NPFKERICRVFS--TSPAKDSLSFEDFLDLLSVFSDTA-TPDIKSHYAFRIF-DFDDDGT 122 N + +VF + ++ L FS TA D AF D D DG Sbjct: 36 NKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGK 95 Query: 123 LNREDLSRLVNC 134 + ++ +V Sbjct: 96 IGVDEFKAMVKA 107 >3DTP-E nrPDB Length = 196 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 28/165 (16%), Positives = 60/165 (36%), Gaps = 19/165 (11%) Query: 22 LTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSP 81 T+ ++ F + + + + + L ++ + + + +P Sbjct: 51 FTQHQVQEFKEAFQLIDQDKDGFISKNDIRA-------TFDSLGRLCTEQELDSMVAEAP 103 Query: 82 AKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGED 141 ++F FL + + AF +FD + DG E L R LT GE Sbjct: 104 --GPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKR---SLTTWGEK 157 Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 + +D L E+ ID +G I++ +F ++++ + Sbjct: 158 FS------QDEVDQALSEAPIDGNGLIDIKKFAQILTKGAKEEGA 196 >5Z1Q-A nrPDB Length = 95 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESD 161 + AF +FD + G+++ +L + L K I ++ E D Sbjct: 23 EEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGF---------DVKKPEILELMNEYD 73 Query: 162 IDRDGTINLSEFQHVIS 178 + +G I +F +++ Sbjct: 74 REGNGYIGFDDFLDIMT 90 Score = 30.1 bits (66), Expect = 0.67, Method: Composition-based stats. Identities = 6/63 (9%), Positives = 20/63 (31%), Gaps = 2/63 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F T+ S+ + + + + +D + +G + +D + Sbjct: 31 EAFDLFDTNK-TGSIDYHELKVAMRALGFDVKK-PEILELMNEYDREGNGYIGFDDFLDI 88 Query: 132 VNC 134 + Sbjct: 89 MTE 91 Score = 28.1 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 10/80 (12%), Positives = 30/80 (37%), Gaps = 4/80 (5%) Query: 24 KQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST--SP 81 +QE+ ++ + + ++ + +++ L + K I + + Sbjct: 18 RQELSEEQKQEIKEAFDLFDTNKTGSIDYHELK--VAMRALGFDVKKPEILELMNEYDRE 75 Query: 82 AKDSLSFEDFLDLLSVFSDT 101 + F+DFLD+++ Sbjct: 76 GNGYIGFDDFLDIMTEKIKN 95 >4MEW-A nrPDB Length = 356 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 65/190 (34%), Gaps = 12/190 (6%) Query: 4 SGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPE 63 L +E Q F + + + + +F EL +++ A+ + Sbjct: 166 QNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHAL----- 220 Query: 64 LKANPFKERICRVFSTSPAK----DSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 + +RI T K +S+ DF+ L D TP Y FR D D Sbjct: 221 --STKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTP-TSIEYWFRCMDLDG 277 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 DG L+ +L + + A + + +L+ +G I L + + Sbjct: 278 DGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLA 337 Query: 180 SPDFASSFKI 189 + F + F I Sbjct: 338 NVFFDTFFNI 347 >3AKA-A nrPDB Length = 166 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 26/77 (33%), Gaps = 12/77 (15%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSA---------SEMKQLIDNILEESDI 162 F FD D +G ++R D S L E S + Q + I +D Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGI---ADR 66 Query: 163 DRDGTINLSEFQHVISR 179 D D I EF + Sbjct: 67 DGDQRITREEFVTGAVK 83 Score = 35.5 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 32/103 (31%), Gaps = 19/103 (18%) Query: 77 FSTSPAKDSLSFEDFLDLLSVFSDTATPD-------IKSHYAFRIFDFDDDGTLNREDLS 129 + ++ E+F+ +V PD H A + D D DG + D + Sbjct: 63 IADRDGDQRITREEFVTG-AVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTA 121 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSE 172 R + + L D D DG + +E Sbjct: 122 RALTAF-----------GVPEDLARQAAAALDTDGDGKVGETE 153 >1N2D-A nrPDB Length = 148 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 54/127 (42%), Gaps = 17/127 (13%) Query: 61 LPELKANPFKERICRVFSTSPA---KDSLSFEDFLDLLSVFSDTATPDIKSH-----YAF 112 L + NP + + + + + SL+ + L+ V K+ AF Sbjct: 30 LRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAF 89 Query: 113 RIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSE 172 ++FD + G ++ DL ++ G +L+ +E +D +L+ ++D +G I+ + Sbjct: 90 QVFDKESTGKVSVGDLRYMLT-----GLGEKLTDAE----VDELLKGVEVDSNGEIDYKK 140 Query: 173 FQHVISR 179 F + R Sbjct: 141 FIEDVLR 147 >1RK9-A nrPDB Length = 110 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 45/111 (40%), Gaps = 9/111 (8%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E I + A DS + F ++ + +A K F + D D G + ++L Sbjct: 9 AEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKV---FHMLDKDKSGFIEEDELG 65 Query: 130 RLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 ++ + + D ++M ++ D D DG I + EF +++ S Sbjct: 66 FILKGFSPDARDLSAKETKM------LMAAGDKDGDGKIGVDEFSTLVAES 110 >4GJF-A nrPDB Length = 89 Score = 40.1 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 10/85 (11%) Query: 96 SVFSDTATPDIKSHYAFRIF-DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 +V T + AF IF +DG ++ ++L +++ L + E++++ID Sbjct: 8 AVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRML-----GQNPTPEELQEMID 62 Query: 155 NILEESDIDRDGTINLSEFQHVISR 179 E D D GT++ EF ++ R Sbjct: 63 ----EVDEDGSGTVDFDEFLVMMVR 83 Score = 34.7 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 7/43 (16%), Positives = 16/43 (37%), Gaps = 2/43 (4%) Query: 61 LPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDT 101 + L NP E + + ++ F++FL ++ Sbjct: 45 MRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKD 87 >3TZ1-A nrPDB Length = 74 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 9/73 (12%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDR 164 + + AFR+ D + G + + L ++ L + I+N++ E+D D Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKS---------LGDELTEDEIENMIAETDTDG 56 Query: 165 DGTINLSEFQHVI 177 GT++ EF+ ++ Sbjct: 57 SGTVDYEEFKCLM 69 >2JOJ-A nrPDB Length = 77 Score = 39.7 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESD 161 + AF +FD + G+++ +L + L K I ++ E D Sbjct: 3 EEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGF---------DVKKPEILELMNEYD 53 Query: 162 IDRDGTINLSEFQHVIS 178 + +G I +F +++ Sbjct: 54 REGNGYIGFDDFLDIMT 70 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 6/63 (9%), Positives = 20/63 (31%), Gaps = 2/63 (3%) Query: 72 RICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRL 131 +F T+ S+ + + + + +D + +G + +D + Sbjct: 11 EAFDLFDTNK-TGSIDYHELKVAMRALGFDVKK-PEILELMNEYDREGNGYIGFDDFLDI 68 Query: 132 VNC 134 + Sbjct: 69 MTE 71 >6EAZ-A nrPDB Length = 379 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 41/113 (36%), Gaps = 13/113 (11%) Query: 77 FSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL- 135 F K +S+ ++L LL++ P H AF++ D D + + R++ +L + Sbjct: 93 FRDLGDKGVISYTEYLFLLTIL---TKPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIIS 149 Query: 136 ---------TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 T E E + E + + ++ EF+ + Sbjct: 150 KQDGFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMEN 202 Score = 32.8 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 19/50 (38%) Query: 90 DFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 +F + V + D F+IFD D D L+ + ++ G Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRMHRG 342 >2W4G-C nrPDB Length = 145 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 42/120 (35%), Gaps = 16/120 (13%) Query: 62 PELKANPFKERICRVF----STSPAKDSLSFEDFLDLL--SVFSDTATPDIKSHYAFRIF 115 L NP I ++ ++FE+FL +L + + R+F Sbjct: 31 RALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVF 90 Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D + +GT+ +L ++ L +M + L + D +G IN F Sbjct: 91 DKEGNGTVMGAELRHVLATL----------GEKMTEEEVEELMKGQEDSNGCINYEAFVK 140 Score = 31.2 bits (69), Expect = 0.30, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 9/75 (12%) Query: 109 HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLI-DNILEESDIDRDGT 167 AF +FD D + + +V L + +E+ +++ + EE + Sbjct: 7 KEAFLLFDRTGDAKITLSQVGDIVRAL-----GQNPTNAEINKILGNPSKEEMNAK---K 58 Query: 168 INLSEFQHVISRSPD 182 I EF ++ + + Sbjct: 59 ITFEEFLPMLQAAAN 73 >3MSE-B nrPDB Length = 180 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 47/111 (42%), Gaps = 6/111 (5%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 RI + + ++++ +F+ + + + +K+ AF D D+DG +++ D+ Sbjct: 76 NRILQALDINDR-GNITYTEFMAGCYRWKNIESTFLKA--AFNKIDKDEDGYISKSDIVS 132 Query: 131 LVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 LV+ + D + + I E I+ I+ EF+ + + Sbjct: 133 LVHDKVLDNNDIDNFFLSVHSIKKGIPREHIIN---KISFQEFKDYMLSTF 180 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 38/94 (40%), Gaps = 12/94 (12%) Query: 95 LSVFSDTATPDIK-SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLI 153 ++ IK + F D + +G+L+ ++ ++ + + K I Sbjct: 27 MAHELSVINNHIKYINELFYKLDTNHNGSLSHREIYTVLASVGIK-----------KWDI 75 Query: 154 DNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 + IL+ DI+ G I +EF R + S+F Sbjct: 76 NRILQALDINDRGNITYTEFMAGCYRWKNIESTF 109 >1A75-A nrPDB Length = 108 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 6/78 (7%) Query: 102 ATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESD 161 AF D D G + ++L + + L+ +E K L+ D Sbjct: 37 GKSADDIKKAFVFIDQDKSGFIEEDELKLFLQ--VFKAGARALTDAETKA----FLKAGD 90 Query: 162 IDRDGTINLSEFQHVISR 179 D DG I + E+ ++ Sbjct: 91 SDGDGAIGVEEWVALVKA 108 >5B7X-A nrPDB Length = 156 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 45/119 (37%), Gaps = 11/119 (9%) Query: 61 LPELKANPFKERICRVFSTSPAKD-SLSFEDFLDLLSV-FSDTATPDIKSHYAFRIFDFD 118 + L P ++ + + + E F ++ S T +IK AF +FD D Sbjct: 39 IRSLGCAPTEDEVNSYIKEFAIEGETFQIEQFELIMEREQSKPDTREIKLRKAFEVFDQD 98 Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 DG + DL+ T + K+ ++ + I + I+L+ F ++ Sbjct: 99 KDGKIKASDLAH---------NLTTVGDKMTKEEVEKVFSILGITMESDIDLATFLKLV 148 Score = 27.8 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 10/75 (13%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 K F +D D DG ++ + L L+ L + E+ I E + Sbjct: 13 QKIRDCFNFYDRDYDGKIDVKQLGTLIRSL-----GCAPTEDEVNSYIKEFAIEGET--- 64 Query: 166 GTINLSEFQHVISRS 180 + +F+ ++ R Sbjct: 65 --FQIEQFELIMERE 77 >4P5X-A nrPDB Length = 315 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 41/113 (36%), Gaps = 9/113 (7%) Query: 66 ANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNR 125 +NP ++ + +S+++FL SV PD AF++FD +G + Sbjct: 56 SNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCA---PDSMFIVAFQLFDKSGNGEVTF 112 Query: 126 EDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 E++ + + + I +R +N +EF + Sbjct: 113 ENVKEIFGQTIIHHHIPF---NWDCEFIRLHFG---HNRKKHLNYTEFTQFLQ 159 Score = 26.6 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 6/67 (8%), Positives = 20/67 (29%), Gaps = 11/67 (16%) Query: 114 IFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 + D DG ++ ++ + L + + D +G + Sbjct: 67 VADQTKDGLISYQEFLAFESVLCA-----------PDSMFIVAFQLFDKSGNGEVTFENV 115 Query: 174 QHVISRS 180 + + ++ Sbjct: 116 KEIFGQT 122 >3JBH-C nrPDB Length = 156 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 45/124 (36%), Gaps = 12/124 (9%) Query: 61 LPELKANPFKERIC-RVFSTSPAKDSLSFEDFLDLLSVFSDTATPD--IKSHYAFRIFDF 117 L L P + S + L+ E+FL + S +++D Sbjct: 36 LRSLDCKPTLAMVKKNGGSDKRGEKKLTLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDK 95 Query: 118 DDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 ++GT+ +L+ ++ L RL+ E ++ I+ D D DG + F I Sbjct: 96 AENGTMLAAELAHVLLSL-----GERLTDIECEE----IMRVCDEDDDGFLKYEPFVKTI 146 Query: 178 SRSP 181 P Sbjct: 147 IAGP 150 Score = 33.1 bits (74), Expect = 0.075, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 10/74 (13%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 K+ F I+D++ +G ++ DL L+ L + + + SD + Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNGG----------SDKRGE 59 Query: 166 GTINLSEFQHVISR 179 + L EF + S+ Sbjct: 60 KKLTLEEFLPIFSQ 73 >2NLN-A nrPDB Length = 108 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 6/66 (9%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D D G L+ ++L + + + L+ SE K L+D +D D DG I Sbjct: 47 FRFIDNDQSGYLDGDELKYFLQKF--QSDARELTESETKSLMDA----ADNDGDGKIGAD 100 Query: 172 EFQHVI 177 EFQ ++ Sbjct: 101 EFQEMV 106 >5CPV-A nrPDB Length = 109 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 32/86 (37%), Gaps = 6/86 (6%) Query: 94 LLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLI 153 + T+ AF I D D G + ++L + + + L+ E K Sbjct: 30 FFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNF--KADARALTDGETK--- 84 Query: 154 DNILEESDIDRDGTINLSEFQHVISR 179 L+ D D DG I + EF ++ Sbjct: 85 -TFLKAGDSDGDGKIGVDEFTALVKA 109 >5VE9-A nrPDB Length = 91 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 26/66 (39%), Gaps = 9/66 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D D DG + R++ + ++A + +I D D DG I+ Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTA------VADIF---DRDGDGYIDYY 83 Query: 172 EFQHVI 177 EF + Sbjct: 84 EFVAAL 89 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 13/31 (41%) Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISRS 180 K + + D D+DG I EF I S Sbjct: 26 KSRVMDFFRRIDKDQDGKITRQEFIDGILAS 56 >5XOP-A nrPDB Length = 66 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 9/65 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ D + DG ++ E++ V ++ A + +QL+ I + D D DG I+ Sbjct: 6 FKEIDVNGDGAVSYEEVKAFV---------SKKRAIKNEQLLQLIFKSIDKDGDGFIDFE 56 Query: 172 EFQHV 176 EF Sbjct: 57 EFAKF 61 Score = 33.1 bits (74), Expect = 0.070, Method: Composition-based stats. Identities = 10/66 (15%), Positives = 26/66 (39%), Gaps = 2/66 (3%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E + + + ++S+E+ +S + F+ D D DG ++ E+ + Sbjct: 2 AEALFKEIDVN-GDGAVSYEEVKAFVSKKRAIKN-EQLLQLIFKSIDKDGDGFIDFEEFA 59 Query: 130 RLVNCL 135 + + Sbjct: 60 KFYGSI 65 Score = 30.1 bits (66), Expect = 0.63, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 18/34 (52%) Query: 152 LIDNILEESDIDRDGTINLSEFQHVISRSPDFAS 185 + + + +E D++ DG ++ E + +S+ + Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN 34 >1QX2-A nrPDB Length = 76 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 33/76 (43%), Gaps = 9/76 (11%) Query: 106 IKSHYAFRIFDFDDD--GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 + AF +F + +++E+L ++ L + +D ++EE D + Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMST-------LDEMIEEVDKN 57 Query: 164 RDGTINLSEFQHVISR 179 DG ++ EF ++ + Sbjct: 58 GDGEVSFEEFLVMMKK 73 >4MSP-A nrPDB Length = 200 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 +SH +F+ D +DD L+++++ + E ++ S L+++I ++ D D+D Sbjct: 127 PRSHESFQEMDLNDDWKLSKDEVKAYLKK-EFEKHGAVVNESHHDALVEDIFDKEDEDKD 185 Query: 166 GTINLSEF 173 G I+ EF Sbjct: 186 GFISAREF 193 Score = 27.4 bits (59), Expect = 4.1, Method: Composition-based stats. Identities = 4/33 (12%), Positives = 14/33 (42%) Query: 155 NILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 +E D++ D ++ E + + + + + Sbjct: 131 ESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAV 163 >1JUO-A nrPDB Length = 198 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 47/129 (36%), Gaps = 21/129 (16%) Query: 63 ELKANPFKERICRVFS---TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 PF CR+ ++ F +F +L +V + F FD D Sbjct: 64 AGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG-------WRQHFISFDTDR 116 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 GT++ ++L + + + RLS Q +++I + + G I ++ + Sbjct: 117 SGTVDPQELQKALTTM-----GFRLS----PQAVNSIAKRYSTN--GKITFDDYIACCVK 165 Query: 180 SPDFASSFK 188 SF+ Sbjct: 166 LRALTDSFR 174 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 DG ++ ++L R + G + + ++ D D GT+ +EF+ + Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMV----SMLDRDMSGTMGFNEFKEL 98 >3I5I-C nrPDB Length = 159 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 31/82 (37%), Gaps = 7/82 (8%) Query: 100 DTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEE 159 DT T + AF+ FD + G ++ ++ ++ L R++ + + + Sbjct: 79 DTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKML-----GERITEDQCNDIF--TFCD 131 Query: 160 SDIDRDGTINLSEFQHVISRSP 181 D DG I + + P Sbjct: 132 IREDIDGNIKYEDLMKKVMAGP 153 >5I2L-A nrPDB Length = 120 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 28/74 (37%), Gaps = 9/74 (12%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 F+ +D DG ++ +L ++ L L +++E D D D Sbjct: 33 MEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKN---------MIKEVDEDFDSK 83 Query: 168 INLSEFQHVISRSP 181 ++ EF + ++ Sbjct: 84 LSFREFLLIFRKAA 97 >2M1U-A nrPDB Length = 93 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 28/80 (35%), Gaps = 10/80 (12%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 S + + AF FD D DG ++ E+ ++ E I E Sbjct: 19 SHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPMTEAE----------ITEFFE 68 Query: 159 ESDIDRDGTINLSEFQHVIS 178 +D + G I+ F ++ Sbjct: 69 AADPNNTGFIDYKAFAAMLY 88 >1TTX-A nrPDB Length = 109 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D D G L+ E+L + E L+ SE K L + +D D DG I Sbjct: 48 FRFIDNDQSGYLDEEELKFFLQKF--ESGARELTESETKSL----MAAADNDGDGKIGAE 101 Query: 172 EFQHVI 177 EFQ ++ Sbjct: 102 EFQEMV 107 >4L9M-A nrPDB Length = 559 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 25/42 (59%) Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 D + + +++++D++ + D D+DG I+ EF+ + + P Sbjct: 414 PDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 26/78 (33%), Gaps = 18/78 (23%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ +D D DG +++E+ ++ D DR+G I+ Sbjct: 431 FKNYDHDQDGYISQEEFEKIAASFPFS------------------FCVMDKDREGLISRD 472 Query: 172 EFQHVISRSPDFASSFKI 189 E R+ S + Sbjct: 473 EITAYFMRASSIYSKLGL 490 Score = 34.3 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 29/73 (39%), Gaps = 16/73 (21%) Query: 62 PELKANPFKERICRVFSTS------PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIF 115 P+ + + R+ + +S E+F + + F ++F + Sbjct: 412 PKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASF----------PFSFCVM 461 Query: 116 DFDDDGTLNREDL 128 D D +G ++R+++ Sbjct: 462 DKDREGLISRDEI 474 >4PAL-A nrPDB Length = 108 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 6/72 (8%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 AF + D D G + ++L + L+ +E K L + D D DG Sbjct: 43 VKKAFYVIDQDKSGFIEEDELKLFLQNF--SPSARALTDAETKA----FLADGDKDGDGM 96 Query: 168 INLSEFQHVISR 179 I + EF +I Sbjct: 97 IGVDEFAAMIKA 108 >2HPS-A nrPDB Length = 186 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 33/82 (40%), Gaps = 2/82 (2%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + T +S +F L T D K+ F DF+ +G ++R++ V Sbjct: 107 MYDCIDT-DKDGYVSLPEFKAFLQAVGPDLT-DDKAITCFNTLDFNKNGQISRDEFLVTV 164 Query: 133 NCLTGEGEDTRLSASEMKQLID 154 N E+T L+ + L+D Sbjct: 165 NDFLFGLEETALANAFYGDLVD 186 Score = 32.4 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 22/62 (35%), Gaps = 9/62 (14%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D D DG ++ + + + L+ + D +++G I+ EF Sbjct: 112 DTDKDGYVSLPEFKAFLQAV-----GPDLTDDK----AITCFNTLDFNKNGQISRDEFLV 162 Query: 176 VI 177 + Sbjct: 163 TV 164 >1BU3-A nrPDB Length = 109 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 39/96 (40%), Gaps = 9/96 (9%) Query: 84 DSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR 143 DS +++ F + + + +A AF + D D G + ++L + Sbjct: 23 DSFNYKAFFAKVGLTAKSADD---IKKAFFVIDQDKSGFIEEDELKLFLQ--VFSAGARA 77 Query: 144 LSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 L+ +E K L+ D D DG I + E+ ++ Sbjct: 78 LTDAETKA----FLKAGDSDGDGAIGVDEWAALVKA 109 >2I18-A nrPDB Length = 64 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 13/70 (18%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 +++ D D DG L +E+ V + +++ M ++D + DG Sbjct: 7 LKVLYKLMDVDGDGKLTKEE----VTSFFKKHGIEKVAEQVM---------KADANGDGY 53 Query: 168 INLSEFQHVI 177 I L EF Sbjct: 54 ITLEEFLEFS 63 >4NSC-A nrPDB Length = 401 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 67 NPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE 126 F + +F T +SF D++ L +V S TP AF++FD + DG ++ E Sbjct: 111 EKFADE-GSIFYTLGECGLISFSDYIFLTTVLS---TPQRNFEIAFKMFDLNGDGEVDME 166 Query: 127 DLSRL 131 + ++ Sbjct: 167 EFEQV 171 Score = 31.2 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 17/30 (56%) Query: 147 SEMKQLIDNILEESDIDRDGTINLSEFQHV 176 S ++ + + D++ DG +++ EF+ V Sbjct: 142 STPQRNFEIAFKMFDLNGDGEVDMEEFEQV 171 >1JF0-A nrPDB Length = 195 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 8/61 (13%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 + + +F +++ +++ S + + F+ D D+ G L+ ++++ Sbjct: 115 GDAVFDIFD-KDGSGTITLDEW-KAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMT 172 Query: 130 R 130 R Sbjct: 173 R 173 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 9/61 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F IFD D GT+ ++ G S + + + D+D G +++ Sbjct: 119 FDIFDKDGSGTITLDEWKA-----YGRISGISPSEEDC----EKTFQHCDLDNSGELDVD 169 Query: 172 E 172 E Sbjct: 170 E 170 Score = 26.6 bits (57), Expect = 7.0, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 15/26 (57%) Query: 149 MKQLIDNILEESDIDRDGTINLSEFQ 174 +++ D + + D D GTI L E++ Sbjct: 111 IREWGDAVFDIFDKDGSGTITLDEWK 136 >2OS8-B nrPDB Length = 157 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 55/163 (33%), Gaps = 19/163 (11%) Query: 20 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 79 T L +++I F + ++ + ++ L P + + + Sbjct: 11 TKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEM-------FSSLGRTPDDKELTAML-- 61 Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 A L+F FL + S + AF +FD D LN E + L+ + Sbjct: 62 KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENM---- 117 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 182 + K + +E+ ++ G + F +I S D Sbjct: 118 -----GDNFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIKGSGD 154 >2MA2-A nrPDB Length = 81 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 D L ++++++++ D+D DG I+ EF +I + + S+F Sbjct: 3 DQALVVEHIEKMVESVFRNFDVDGDGHISQEEF-QIIRGNFPYLSAF 48 Score = 34.7 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 27/74 (36%), Gaps = 16/74 (21%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR FD D DG +++E+ + G LS + D ++DG I+ Sbjct: 19 FRNFDVDGDGHISQEEFQII------RGNFPYLS----------AFGDLDQNQDGCISRE 62 Query: 172 EFQHVISRSPDFAS 185 E RS Sbjct: 63 EMVSYFLRSSSVLG 76 Score = 30.8 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 24/62 (38%), Gaps = 9/62 (14%) Query: 67 NPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE 126 E + R F +S E+F + F + AF D + DG ++RE Sbjct: 12 EKMVESVFRNFD-VDGDGHISQEEFQIIRGNFPYLS--------AFGDLDQNQDGCISRE 62 Query: 127 DL 128 ++ Sbjct: 63 EM 64 >5MRA-A nrPDB Length = 167 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 47/129 (36%), Gaps = 21/129 (16%) Query: 63 ELKANPFKERICRVFS---TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 PF CR+ ++ F +F +L +V + F FD D Sbjct: 33 AGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG-------WRQHFISFDTDR 85 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 GT++ ++L + + + RLS Q +++I + + G I ++ + Sbjct: 86 SGTVDPQELQKALTTM-----GFRLS----PQAVNSIAKRYSTN--GKITFDDYIACCVK 134 Query: 180 SPDFASSFK 188 SF+ Sbjct: 135 LRALTDSFR 143 Score = 28.5 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 DG ++ ++L R + G + + ++ D D GT+ +EF+ + Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMV----SMLDRDMSGTMGFNEFKEL 67 >2L50-A nrPDB Length = 102 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 20/42 (47%) Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 + + + LS + ++ D +++ D + DG I+ E+ Sbjct: 37 FREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEY 78 >1S6J-A nrPDB Length = 87 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 F++ D D+ GT+ ++L + R+ + M+ I ++++ +DID+ GT Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLK---------RVGSELMESEIKDLMDAADIDKSGT 75 Query: 168 INLSEFQ 174 I+ EF Sbjct: 76 IDYGEFI 82 Score = 27.4 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 142 TRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 RLS E+ L + + D D GTI E + + R Sbjct: 15 ERLSEEEIGGL-KELFKMIDTDNSGTITFDELKDGLKR 51 >1CB1-A nrPDB Length = 78 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 15/71 (21%) Query: 124 NREDLSRLV-NCLTGEGEDTRLSASEMKQLI--------------DNILEESDIDRDGTI 168 + +L + EG+ +LS E+KQLI D++ +E D + DG + Sbjct: 5 SPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEV 64 Query: 169 NLSEFQHVISR 179 + EFQ ++ + Sbjct: 65 SFEEFQVLVKK 75 >3KPX-A nrPDB Length = 198 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E + +F S+S +++ + S D + F+ D D+ G L+ ++++ Sbjct: 118 GEAVFDIFD-KDGSGSISLDEWKTYGGI-SGICPSDEDAEKTFKHCDLDNSGKLDVDEMT 175 Query: 130 R 130 R Sbjct: 176 R 176 Score = 34.7 bits (78), Expect = 0.026, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 24/61 (39%), Gaps = 9/61 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F IFD D G+++ ++ G S + + + D+D G +++ Sbjct: 122 FDIFDKDGSGSISLDEWK-----TYGGISGICPSDED----AEKTFKHCDLDNSGKLDVD 172 Query: 172 E 172 E Sbjct: 173 E 173 Score = 31.2 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 11/86 (12%), Positives = 32/86 (37%), Gaps = 5/86 (5%) Query: 96 SVFSDTATPDIKS----HYAFRIFDFDDDGTLNREDL-SRLVNCLTGEGEDTRLSASEMK 150 +V T D K + F D + +G + +++ S+ + + + T + Sbjct: 9 AVKLKTNFEDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQ 68 Query: 151 QLIDNILEESDIDRDGTINLSEFQHV 176 + ++ ++ +D + F + Sbjct: 69 EAVEAFFKKIGLDYGKEVEFPAFVNG 94 >6AGI-A nrPDB Length = 382 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 33/77 (42%), Gaps = 3/77 (3%) Query: 75 RVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNC 134 ++F K +S+ ++L LL + P AF +FD D + +++++ L Sbjct: 77 KLFRNLKEKGVISYTEYLFLLCIL---TKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEI 133 Query: 135 LTGEGEDTRLSASEMKQ 151 + E + E K+ Sbjct: 134 FRKKNEKREIKGDEEKR 150 Score = 29.7 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 50/132 (37%), Gaps = 14/132 (10%) Query: 48 SLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIK 107 + ++ F IL L + V + P + ++F++F ++ Sbjct: 254 NTISEEDFAHIL-LRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLED---- 308 Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 A +++F ++ +++ R V TG L ++ + + D+D+D Sbjct: 309 FAIALNMYNF-ASRSIGQDEFKRAVYVATGLKFSPHL--------VNTVFKIFDVDKDDQ 359 Query: 168 INLSEFQHVISR 179 ++ EF ++ Sbjct: 360 LSYKEFIGIMKD 371 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 31/94 (32%), Gaps = 4/94 (4%) Query: 46 ESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPD 105 E F N ++ + + A S+ ++F + V + Sbjct: 287 EEKGITFDEFRSFFQF----LNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSP 342 Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 + F+IFD D D L+ ++ ++ G Sbjct: 343 HLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRG 376 >1S36-A nrPDB Length = 195 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 50/133 (37%), Gaps = 11/133 (8%) Query: 6 SRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPE 63 S+ S ++ A+ + TK+ + F E + + F+Q+ + L + Sbjct: 44 SKASDDICAKLEATPEQTKRH-QVCVEAFFRGCGMEYGKEIAFPQFLDGFKQLATSELKK 102 Query: 64 LKANP------FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDF 117 N + + + +F +++ +++ S + FR D Sbjct: 103 WARNEPTLIREWGDAVFDIFD-KDGSGTITLDEW-KAYGKISGISPSQEDCEATFRHCDL 160 Query: 118 DDDGTLNREDLSR 130 D+ G L+ ++++R Sbjct: 161 DNSGDLDVDEMTR 173 Score = 34.3 bits (77), Expect = 0.036, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 37/101 (36%), Gaps = 27/101 (26%) Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYA--------------FRIFDFDDDGTLNREDLSRL 131 ++F FLD F AT ++K +A F IFD D GT+ ++ Sbjct: 83 IAFPQFLDG---FKQLATSELK-KWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKA- 137 Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSE 172 G+ S + + D+D G +++ E Sbjct: 138 ----YGKISGISPSQEDC----EATFRHCDLDNSGDLDVDE 170 Score = 26.2 bits (56), Expect = 8.3, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 16/30 (53%) Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQ 174 + +++ D + + D D GTI L E++ Sbjct: 107 EPTLIREWGDAVFDIFDKDGSGTITLDEWK 136 >1TIZ-A nrPDB Length = 67 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 28/68 (41%), Gaps = 9/68 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F FD + DG L+ ++ + S ++ I EE D+D +G +N Sbjct: 7 FEKFDKNKDGKLSLDEFREVALA---------FSPYFTQEDIVKFFEEIDVDGNGELNAD 57 Query: 172 EFQHVISR 179 EF I + Sbjct: 58 EFTSCIEK 65 Score = 30.4 bits (67), Expect = 0.51, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 +R+ F + LS ++F ++ FS T + + F D D +G LN ++ + Sbjct: 3 AKRVFEKFDKNK-DGKLSLDEFREVALAFSPYFTQEDIVKF-FEEIDVDGNGELNADEFT 60 Query: 130 RLVNCLT 136 + + Sbjct: 61 SCIEKML 67 Score = 29.7 bits (65), Expect = 0.90, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 15/23 (65%) Query: 154 DNILEESDIDRDGTINLSEFQHV 176 + E+ D ++DG ++L EF+ V Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREV 26 >4NQG-A nrPDB Length = 197 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 9/61 (14%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 + + + S+S ++++ + + + F D D DG L+ ++++ Sbjct: 116 GDALFDIID-KDGNGSVSLDEWIQY-THCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMT 173 Query: 130 R 130 R Sbjct: 174 R 174 Score = 34.3 bits (77), Expect = 0.029, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 27/61 (44%), Gaps = 9/61 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F I D D +G+++ ++ + +C + + + + D+D DG +++ Sbjct: 120 FDIIDKDGNGSVSLDEWIQYTHCAGIQ---------QSRGQCEATFAHCDLDGDGKLDVD 170 Query: 172 E 172 E Sbjct: 171 E 171 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 15/119 (12%), Positives = 36/119 (30%), Gaps = 20/119 (16%) Query: 72 RICRVFSTSPAKDSLSFEDFL--------DLLSVFSDTATPDIKSHYAF-----RIFDFD 118 + + + ++ + + L + K F +D D Sbjct: 25 HMFNFLDIN-SNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLEYDKD 83 Query: 119 DD--GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 + E RL R++ ++ D + + D D +G+++L E+ Sbjct: 84 TTWPEYI--EGWKRLAKTELERHSKNRVT--LIRLWGDALFDIIDKDGNGSVSLDEWIQ 138 >1ZFS-A nrPDB Length = 93 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 27/56 (48%), Gaps = 4/56 (7%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 L++++L L+ D + A +D I++E D + DG ++ EF ++ Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADA----VDKIMKELDENGDGEVDFQEFVVLV 78 >2PMY-A nrPDB Length = 91 Score = 35.5 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 23/78 (29%), Gaps = 11/78 (14%) Query: 99 SDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILE 158 + F D + G L RE+ L L D + + + Sbjct: 20 DGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPAD-----------AEAVFQ 68 Query: 159 ESDIDRDGTINLSEFQHV 176 D DRDG I EF Sbjct: 69 RLDADRDGAITFQEFARG 86 >2EC6-B nrPDB Length = 133 Score = 35.5 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 40/118 (33%), Gaps = 12/118 (10%) Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 L P + + + A L+F FL + S + AF +FD D Sbjct: 28 FSSLGRTPDDKELTAML--KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDEDAT 85 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 LN E + L+ + + K + +E+ ++ G + F +I Sbjct: 86 KKLNIEYIKDLLENM---------GDNFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIK 133 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 18/40 (45%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 + AF + D + DG ++ DL + L +D L+ Sbjct: 2 QEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELT 41 >6AGH-A nrPDB Length = 339 Score = 35.5 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 47/114 (41%), Gaps = 15/114 (13%) Query: 77 FSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 F K +S+ ++L LL++ P H AF++ D D + + + + +L ++ Sbjct: 90 FRDLGDKGLISYTEYLFLLTIL---TKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIIS 146 Query: 137 GEGEDTRLSASEMKQLIDNILEESDID-----------RDGTINLSEFQHVISR 179 + + + +E + I++E +I+ ++ EF+ + Sbjct: 147 KQDDLMTVKTNETGYQ-EAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMEN 199 Score = 30.8 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%) Query: 90 DFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 +F + V + + F+IFD D D L+ E+ ++ G Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRMHRG 339 >3CS1-A nrPDB Length = 219 Score = 35.5 bits (80), Expect = 0.016, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 30/93 (32%), Gaps = 9/93 (9%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 K S F +FL+ + F D + ++ E+ R V L G Sbjct: 106 ENKGSEDFVEFLEFRLMLCYIYDFFE-LTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGA 164 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 A + +E D + G++ EF Sbjct: 165 KVEDPA--------ALFKELDKNGTGSVTFDEF 189 >1G33-A nrPDB Length = 73 Score = 35.5 bits (80), Expect = 0.016, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 F I D D G + ++L ++ + + D + ++ D D DG Sbjct: 7 VKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKET------KTLMAAGDKDGDGK 60 Query: 168 INLSEFQHVISRS 180 I + EF +++ S Sbjct: 61 IGVEEFSTLVAES 73 >4I5K-A nrPDB Length = 285 Score = 35.1 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 57/170 (33%), Gaps = 13/170 (7%) Query: 11 ELLAEYQDLT-FLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPF 69 E + +T + + + + + +F EL + + ++ + ++ Sbjct: 98 EEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYN-------DQASSSRI 150 Query: 70 KERICRVFSTSPAK----DSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNR 125 ERI T +S+ DF+ L D P Y FR D D DG L+ Sbjct: 151 IERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNP-TSIEYWFRCMDVDGDGVLSM 209 Query: 126 EDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 +L E + L+ +L+ DG I L + + Sbjct: 210 YELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKR 259 >4OCI-A nrPDB Length = 146 Score = 35.1 bits (79), Expect = 0.020, Method: Composition-based stats. Identities = 18/129 (13%), Positives = 46/129 (35%), Gaps = 11/129 (8%) Query: 47 SSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDI 106 FE ++ + + I ++++ +S+E F S + Sbjct: 20 DGYLTLNEFESLVRVLGVVMETSA--IASTYNSNSKVRGMSYELFTSCFSQLKTKSFNKD 77 Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + A + D D G + +L R++ + + + ++ I ++ ID G Sbjct: 78 EIKTAINVLDKDKKGFIPAIELRRIL---------STIGDNMEQKEITDLFTFMGIDEQG 128 Query: 167 TINLSEFQH 175 + + +F + Sbjct: 129 VVKVDDFIN 137 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 105 DIKSHYAFRIFDFDDDGTLNREDLSRLVNCL 135 + +F +FD D DG L + LV L Sbjct: 5 NEDLKESFLLFDGDGDGYLTLNEFESLVRVL 35 >1QLS-A nrPDB Length = 99 Score = 34.7 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 ++ +++ + +N + + D ++++ D+D DG ++ EF ++I Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDPGVL----DRMMKKLDLDSDGQLDFQEFLNLI 82 Score = 26.2 bits (56), Expect = 8.0, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 28/73 (38%), Gaps = 4/73 (5%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIK----SHYAFRIFDFDDDGTLNREDLSRLVNCL 135 +S +FL ++ T + K + D D DG L+ ++ L+ L Sbjct: 26 DGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLIGGL 85 Query: 136 TGEGEDTRLSASE 148 D+ + +++ Sbjct: 86 AIACHDSFIKSTQ 98 >5H53-B nrPDB Length = 146 Score = 34.7 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 25/69 (36%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 A ++F FL + A P+ AF++ D + GT+ ++ L L+ Sbjct: 49 KEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQCDRF 108 Query: 140 EDTRLSASE 148 + Sbjct: 109 SQEEIKNMW 117 Score = 30.4 bits (67), Expect = 0.42, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQ 151 + AF + D + DG +++EDL + + MK+ Sbjct: 5 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKE 50 >1B7T-Y nrPDB Length = 156 Score = 34.7 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 37/101 (36%), Gaps = 10/101 (9%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 A L+F FL + S + AF +FD + LN E + L+ + Sbjct: 61 KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENM---- 116 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 + K + +E+ ++ G + +F +I S Sbjct: 117 -----GDNFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIKGS 151 >5VT9-A nrPDB Length = 152 Score = 34.7 bits (78), Expect = 0.027, Method: Composition-based stats. Identities = 16/108 (14%), Positives = 30/108 (27%), Gaps = 12/108 (11%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 + F D+L + F + + AF FD G L R+ + ++ Sbjct: 56 KQAFEEKSG-DNLDYASFQKFVGTSTHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNILM 114 Query: 134 CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 L+ E L I+ +F + + Sbjct: 115 T-----YGEPLTTEEFNALAAEYFTS------DQIDYRQFCKAMLEAA 151 >3TS5-B nrPDB Length = 161 Score = 34.7 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 42/122 (34%), Gaps = 12/122 (9%) Query: 61 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD 120 L P + + + A L+F FL + S + AF +FD D Sbjct: 49 FSSLGRTPDDKELTAML--KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDT 106 Query: 121 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180 LN E + L+ + + K + +E+ ++ G + F +I S Sbjct: 107 KKLNIEYIKDLLENM---------GDNFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIKGS 156 Query: 181 PD 182 D Sbjct: 157 GD 158 Score = 31.2 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 19/40 (47%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 + AF + D + DG ++ DL + + L +D L+ Sbjct: 23 QEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELT 62 >2FCE-A nrPDB Length = 70 Score = 34.3 bits (77), Expect = 0.030, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 36/69 (52%), Gaps = 9/69 (13%) Query: 111 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 170 AF++FD + G ++ DL ++ G +L+ +E +D +L+ ++D +G I+ Sbjct: 10 AFQVFDKESTGKVSVGDLRYMLT-----GLGEKLTDAE----VDELLKGVEVDSNGEIDY 60 Query: 171 SEFQHVISR 179 +F + R Sbjct: 61 KKFIEDVLR 69 >3A8R-A nrPDB Length = 179 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 41/100 (41%), Gaps = 5/100 (5%) Query: 87 SFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSA 146 +DF + L+ D + F + D + DG L E++ ++ L+ Sbjct: 83 ELKDFYEQLT----DQGFDNRLRTFFDMVDKNADGRLTAEEVKEII-ALSASANKLSKIK 137 Query: 147 SEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASS 186 + I+EE D G I + + + ++ +SP A++ Sbjct: 138 ERADEYTALIMEELDPTNLGYIEMEDLEALLLQSPSEAAA 177 Score = 33.1 bits (74), Expect = 0.070, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 28/73 (38%), Gaps = 3/73 (4%) Query: 109 HYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTI 168 +A ++FD R + +++ + +L+ + + D + DG + Sbjct: 59 EFAVQMFDSLAR---KRGIVKQVLTKDELKDFYEQLTDQGFDNRLRTFFDMVDKNADGRL 115 Query: 169 NLSEFQHVISRSP 181 E + +I+ S Sbjct: 116 TAEEVKEIIALSA 128 >1SL8-A nrPDB Length = 191 Score = 34.3 bits (77), Expect = 0.032, Method: Composition-based stats. Identities = 8/61 (13%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 + + + ++S +++ + + FR+ D D+ G L+ ++++ Sbjct: 111 GDALFDIID-KDQNGAISLDEW-KAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMT 168 Query: 130 R 130 R Sbjct: 169 R 169 Score = 30.8 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 22/61 (36%), Gaps = 9/61 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F I D D +G ++ ++ T + S + DID G +++ Sbjct: 115 FDIIDKDQNGAISLDEW----KAYTKSAGIIQSSED-----CEETFRVCDIDESGQLDVD 165 Query: 172 E 172 E Sbjct: 166 E 166 Score = 27.4 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 22/42 (52%), Gaps = 6/42 (14%) Query: 154 DNILEESDIDRDGTINLSEFQH------VISRSPDFASSFKI 189 D + + D D++G I+L E++ +I S D +F++ Sbjct: 112 DALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRV 153 >4D1E-A nrPDB Length = 876 Score = 34.3 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 16/114 (14%), Positives = 45/114 (39%), Gaps = 6/114 (5%) Query: 17 QDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRV 76 +D +T++++ F ++ ++ + ++S+ RI + Sbjct: 727 RDAKGITQEQMNEFRASFNHFDRRKNGLMDH----EDFRACLISMGYDLGEAEFARIMTL 782 Query: 77 FSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 + + +++F+ F+D ++ + + +FRI D + E+L R Sbjct: 783 VDPN-GQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP-YILAEELRR 834 Score = 33.9 bits (76), Expect = 0.046, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 27/74 (36%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + +F FD +G ++ ED + + L +E I+ D + G Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISM-----GYDLGEAEFA----RIMTLVDPNGQG 789 Query: 167 TINLSEFQHVISRS 180 T+ F ++R Sbjct: 790 TVTFQSFIDFMTRE 803 >5MKE-A nrPDB Length = 968 Score = 33.9 bits (76), Expect = 0.039, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 26/71 (36%), Gaps = 3/71 (4%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 L+F++ L D + F +D D D L + ++ + L E E Sbjct: 731 QGGGKLNFDELRQDL---KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERE 787 Query: 141 DTRLSASEMKQ 151 D L S + + Sbjct: 788 DLDLDHSSLPR 798 >1DFK-Y nrPDB Length = 139 Score = 33.9 bits (76), Expect = 0.041, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 36/99 (36%), Gaps = 10/99 (10%) Query: 80 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 139 A L+F FL + S + AF +FD + LN E + L+ + Sbjct: 50 KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENM---- 105 Query: 140 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 + K + +E+ ++ G + +F +I Sbjct: 106 -----GDNFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIK 138 >1KQV-A nrPDB Length = 79 Score = 33.9 bits (76), Expect = 0.043, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 17/27 (62%) Query: 153 IDNILEESDIDRDGTINLSEFQHVISR 179 +D + EE D + DG ++ EFQ ++ + Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKK 76 >2LUC-A nrPDB Length = 105 Score = 33.9 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 27/62 (43%), Gaps = 7/62 (11%) Query: 119 DDGT---LNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 DG L++ + +N + + D ++++ D + DG ++ SEF + Sbjct: 27 KDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL----DRMMKKLDTNSDGQLDFSEFLN 82 Query: 176 VI 177 +I Sbjct: 83 LI 84 >1BOD-A nrPDB Length = 74 Score = 33.5 bits (75), Expect = 0.051, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 7/74 (9%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 + F +D + DG LS+ L + E L +D + EE D + D Sbjct: 5 EELKGIFEKYDKEGDG-----QLSKEELKLLLQTEFPSLLKGM--STLDELFEELDKNGD 57 Query: 166 GTINLSEFQHVISR 179 G ++ EFQ ++ + Sbjct: 58 GEVSFEEFQVLVKK 71 >2N8Y-A nrPDB Length = 153 Score = 33.5 bits (75), Expect = 0.057, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 27/74 (36%), Gaps = 4/74 (5%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + +F FD D GTL E+ + L + + + I+ D +R G Sbjct: 11 EFRASFNHFDRDHSGTLGPEEFKACLISL----GYDIGNDPQGEAEFARIMSIVDPNRLG 66 Query: 167 TINLSEFQHVISRS 180 + F +SR Sbjct: 67 VVTFQAFIDFMSRE 80 Score = 32.8 bits (73), Expect = 0.100, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 26/60 (43%), Gaps = 2/60 (3%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 RI + + ++F+ F+D +S + + +F+I D + + ++L R Sbjct: 54 ARIMSIVDPNRL-GVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRR 111 >1GJY-A nrPDB Length = 167 Score = 33.5 bits (75), Expect = 0.061, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 42/129 (32%), Gaps = 21/129 (16%) Query: 63 ELKANPFKERICRVFS---TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 119 PF CR+ ++ F +F +L +V + F FD D Sbjct: 33 AGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG-------WRQHFISFDSDR 85 Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 GT++ ++L + + + RL+ + + G I ++ + Sbjct: 86 SGTVDPQELQKALTTM-----GFRLNPQTVNSIAKRY------STSGKITFDDYIACCVK 134 Query: 180 SPDFASSFK 188 SF+ Sbjct: 135 LRALTDSFR 143 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 DG ++ ++L R + G + + ++ D D GT+ +EF+ + Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMV----SMLDRDMSGTMGFNEFKEL 67 >3H4S-E nrPDB Length = 135 Score = 33.5 bits (75), Expect = 0.062, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 88 FEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSAS 147 +ED L +++ D + F + + + E L R +G +S Sbjct: 22 YEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESLRR----NSGILGIEGMSKE 77 Query: 148 EMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + + ++ E D+D DG +N +EF ++ R Sbjct: 78 DAQGMV----REGDLDGDGALNQTEFCVLMVR 105 >1SJJ-A nrPDB Length = 863 Score = 33.5 bits (75), Expect = 0.063, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 26/60 (43%), Gaps = 2/60 (3%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 RI + + ++F+ F+D +S + + +F+I D + + ++L R Sbjct: 764 ARIMSIVDPNRM-GVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITVDELRR 821 Score = 29.7 bits (65), Expect = 0.86, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 26/74 (35%), Gaps = 9/74 (12%) Query: 107 KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 + +F FD G ++ ED + + + +E I+ D +R G Sbjct: 726 EFRASFNHFDRKKTGMMDCEDFRACLISM-----GYNMGEAEFA----RIMSIVDPNRMG 776 Query: 167 TINLSEFQHVISRS 180 + F +SR Sbjct: 777 VVTFQAFIDFMSRE 790 >6DU8-A nrPDB Length = 805 Score = 33.1 bits (74), Expect = 0.067, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 41/116 (35%), Gaps = 6/116 (5%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 + + FEDF + L + F FD D + L+ ++ ++ L E Sbjct: 611 GGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERV 670 Query: 141 DTRLSASEMKQLIDNILE-----ESDIDRDGTINLSEFQHVISRSPDFASSFKIVL 191 ++ + I + + E+ G ++ EF + R + + V+ Sbjct: 671 ALNTEIEKLGRSIVSSPQGKSGPEAARAG-GWVSGEEFYMLTRRVLQLETVLEGVV 725 >6MI5-X nrPDB Length = 117 Score = 33.1 bits (74), Expect = 0.068, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 37/103 (35%), Gaps = 18/103 (17%) Query: 74 CRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS-RLV 132 F ++ ++ L S AF D D DGTL+ ++L R+ Sbjct: 9 IAAFDP-DKDGTIDLKEALAAGSA-------------AFDKLDPDKDGTLDAKELKGRVS 54 Query: 133 NCLTGE---GEDTRLSASEMKQLIDNILEESDIDRDGTINLSE 172 + D L E ++ + ++ D DGTI+ E Sbjct: 55 EADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDARE 97 >1NSH-A nrPDB Length = 101 Score = 33.1 bits (74), Expect = 0.074, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 TL++ + +N + + D ++++ D++ DG ++ EF ++I Sbjct: 29 TLSKTEFLSFMNTELAAFTKNQKDPGVL----DRMMKKLDLNSDGQLDFQEFLNLI 80 Score = 26.2 bits (56), Expect = 9.6, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 71 ERICRVFSTSPAKD----SLSFEDFLDLLSVFSDTATPDIK----SHYAFRIFDFDDDGT 122 E + VF KD +LS +FL ++ T + K + D + DG Sbjct: 11 ESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQ 70 Query: 123 LNREDLSRLVNCLTGEGEDTRLSASEMKQL 152 L+ ++ L+ L ++ + A+ ++ Sbjct: 71 LDFQEFLNLIGGLAVACHESFVKAAPPQKR 100 >2M7M-A nrPDB Length = 66 Score = 33.1 bits (74), Expect = 0.076, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 31/65 (47%), Gaps = 9/65 (13%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F+ D + DG ++ E++ V ++ A + +QL+ I + D D +G I+ + Sbjct: 6 FKEIDVNGDGAVSYEEVKAFV---------SKKRAIKNEQLLQLIFKSIDADGNGEIDQN 56 Query: 172 EFQHV 176 EF Sbjct: 57 EFAKF 61 Score = 30.8 bits (68), Expect = 0.38, Method: Composition-based stats. Identities = 7/67 (10%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 E + + + ++S+E+ + + F+ D D +G +++ + + Sbjct: 2 AEALFKEIDVN-GDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFA 59 Query: 130 RLVNCLT 136 + + Sbjct: 60 KFYGSIQ 66 Score = 30.8 bits (68), Expect = 0.39, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 18/34 (52%) Query: 152 LIDNILEESDIDRDGTINLSEFQHVISRSPDFAS 185 + + + +E D++ DG ++ E + +S+ + Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN 34 >2WCE-A nrPDB Length = 95 Score = 33.1 bits (74), Expect = 0.078, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 29/64 (45%), Gaps = 4/64 (6%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 TL++ +L +L+ + K +ID I + D ++D ++ EF +++ + Sbjct: 30 TLSKGELKQLLTKELA-NTIKNIKD---KAVIDEIFQGLDANQDEQVDFQEFISMVAIAL 85 Query: 182 DFAS 185 A Sbjct: 86 KAAH 89 >2MBX-A nrPDB Length = 109 Score = 33.1 bits (74), Expect = 0.078, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 6/72 (8%) Query: 108 SHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGT 167 F I D D + ++L + + + +++ L+ D D DG Sbjct: 44 IKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKV------FLKAGDSDGDGK 97 Query: 168 INLSEFQHVISR 179 I + EF +I Sbjct: 98 IGVDEFGAMIKA 109 >5W1A-B nrPDB Length = 155 Score = 33.1 bits (74), Expect = 0.081, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 48/126 (38%), Gaps = 10/126 (7%) Query: 60 SLPELKANPFKERICRVFSTSPAKDS-LSFEDFLDLLSVFSDTATP--DIKSHYAFRIFD 116 +L L NP I ++ T + + ++FL + S +++D Sbjct: 34 ALRALNLNPTLALIEKLGGTKKRNEKKIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYD 93 Query: 117 FDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 +++GT+ +L + L L +++ L + ++ D +G I S F Sbjct: 94 KEENGTMLLAELQHALLAL-----GESLDDEQVETLFADCMDPED--DEGFIPYSPFLAR 146 Query: 177 ISRSPD 182 + PD Sbjct: 147 MCDRPD 152 >6D1W-A nrPDB Length = 740 Score = 32.8 bits (73), Expect = 0.086, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 23/65 (35%), Gaps = 3/65 (4%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 L+F++ L D + F +D D D L + ++ + L E E Sbjct: 679 QGGGKLNFDELRQDL---KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERE 735 Query: 141 DTRLS 145 D L Sbjct: 736 DLDLD 740 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 25/58 (43%), Gaps = 11/58 (18%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHV 176 G LN ++L + L G+G + +E I+ I + D D D + E Q + Sbjct: 680 GGGKLNFDELRQ---DLKGKGH----TDAE----IEAIFTKYDQDGDQELTEHEHQQM 726 >1Q80-A nrPDB Length = 174 Score = 32.8 bits (73), Expect = 0.096, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 26/63 (41%), Gaps = 11/63 (17%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 FR D ++D ++R++ + + G K + + D + DG ++L Sbjct: 100 FRAVDTNEDNNISRDE-YGIFFGMLGLD----------KTMAPASFDAIDTNNDGLLSLE 148 Query: 172 EFQ 174 EF Sbjct: 149 EFV 151 Score = 27.0 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 13/35 (37%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 K F DFD DG + R D + E E Sbjct: 6 QKMKTYFNRIDFDKDGAITRMDFESMAERFAKESE 40 >2L0P-A nrPDB Length = 94 Score = 32.4 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 L++++L L+ D + +D +++E D + DG ++ E+ ++ Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDA----VDKVMKELDENGDGEVDFQEYVVLV 79 >3RNC-B nrPDB Length = 330 Score = 32.4 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 6/72 (8%), Positives = 26/72 (36%), Gaps = 1/72 (1%) Query: 27 ILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSL 86 + ++++C P + + + +L + + + + + D + Sbjct: 54 MQTWYKKYCFDSPLKHDDWNAFRDPDQLVYRTYNLLQDGQESYVQGLFDQLN-DRGHDQM 112 Query: 87 SFEDFLDLLSVF 98 ++++ L+ F Sbjct: 113 LTREWVETLARF 124 >1IJ5-A nrPDB Length = 323 Score = 32.4 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 22/134 (16%), Positives = 54/134 (40%), Gaps = 16/134 (11%) Query: 44 SVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTAT 103 + + ++ F + ++ + R + D + F +++ L Sbjct: 199 TNSNGTLSRKEFREHFVRLGFDKKSVQDALFRYADEDESDD-VGFSEYVHLGLCLLV--- 254 Query: 104 PDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 ++ YAF DFD G L++E++ +++ ED + S K+ ++ D+D Sbjct: 255 --LRILYAF--ADFDKSGQLSKEEVQKVL-------EDAHIPESARKKF-EHQFSVVDVD 302 Query: 164 RDGTINLSEFQHVI 177 +++ EF ++ Sbjct: 303 DSKSLSYQEFVMLV 316 Score = 27.0 bits (58), Expect = 5.6, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 33/98 (33%), Gaps = 16/98 (16%) Query: 78 STSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 S SF+D +L+ P+ F + + D G ++ L + N L Sbjct: 131 SAVSGSGKFSFQDLKQVLA-KYADTIPEGPLKKLFVMVENDTKGRMSYITLVAVANDLAA 189 Query: 138 EGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D + D + +GT++ EF+ Sbjct: 190 LVAD---------------FRKIDTNSNGTLSRKEFRE 212 >1QXP-A nrPDB Length = 900 Score = 32.4 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 58/187 (31%), Gaps = 20/187 (10%) Query: 5 GSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL 64 L ++ A D L+++EI + L + + + I +L Sbjct: 510 TQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRIISKHKDL 569 Query: 65 KANPFKERICRV---FSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDG 121 + N F CR L +F L + + T FR FD D G Sbjct: 570 RTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTI-------FRKFDLDKSG 622 Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 +++ ++ + E +L + ++ D + I+ F + R Sbjct: 623 SMSAYEMR-----MAIEAAGFKLPCQLHQVIVARF-----ADDELIIDFDNFVRCLVRLE 672 Query: 182 DFASSFK 188 FK Sbjct: 673 ILFKIFK 679 Score = 27.8 bits (60), Expect = 2.7, Method: Composition-based stats. Identities = 18/149 (12%), Positives = 50/149 (33%), Gaps = 23/149 (15%) Query: 27 ILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPE-LKANPFKERICRVFSTSPAKDS 85 + + + F +L P+ +++ L + + F + L ++ + + +++ Sbjct: 671 LEILFKIFKQLDPENTGTIQLDLISWLSFSVLGKLAAAIEHHHHHHMHYSNIEANESEEE 730 Query: 86 LSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLS 145 F L+ DD ++ +L ++N + D + + Sbjct: 731 RQFRKLFVQLAG---------------------DDMEVSATELMNILNKVVTRHPDLK-T 768 Query: 146 ASEMKQLIDNILEESDIDRDGTINLSEFQ 174 +++ D D G + EF+ Sbjct: 769 DGFGIDTCRSMVAVMDSDTTGKLGFEEFK 797 >2AUC-A nrPDB Length = 126 Score = 32.4 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 23/50 (46%) Query: 84 DSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 DSL++E +L+ L++ + F FD + G L + + ++ Sbjct: 43 DSLTYEQYLEYLTMCVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILT 92 >4AOM-A nrPDB Length = 146 Score = 32.4 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 23/50 (46%) Query: 84 DSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVN 133 D+L++E +L+ LS+ + F FD + G L + + ++ Sbjct: 62 DNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILT 111 >2LVV-A nrPDB Length = 226 Score = 32.0 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 29/103 (28%), Gaps = 9/103 (8%) Query: 71 ERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130 ++ + + +FL+ + F D D L ++ Sbjct: 99 DKAKDLGNKVKGVGEEDLVEFLEFRLMLCYIYDIFE-LTVMFDTMDKDGSLLLELQEFKE 157 Query: 131 LVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 + L G D + + + E D + G + EF Sbjct: 158 ALPKLKEWGVDITDATT--------VFNEIDTNGSGVVTFDEF 192 Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 100 DTATPDIKSH--YAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNIL 157 + KS F+ FD + G L ++ + E T + + ++ Sbjct: 43 RDKDAESKSRRIELFKQFDTNGTGKLGFREVLDGCYGILKLDEFT----THLPDIVQRAF 98 Query: 158 EES-----DIDRDGTINLSEFQHV 176 +++ + G +L EF Sbjct: 99 DKAKDLGNKVKGVGEEDLVEFLEF 122 Score = 26.6 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 33/117 (28%), Gaps = 19/117 (16%) Query: 72 RICRVFSTSPAKDSLSFEDFLDL-LSVFSDTATPDIKSHYAFRIFDFDDD--------GT 122 + + F T+ L F + LD + R FD D G Sbjct: 55 ELFKQFDTN-GTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGE 113 Query: 123 LNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 + + L + L+ + + D D + L EF+ + + Sbjct: 114 EDLVEFLEFRLMLCYIYDIFELT---------VMFDTMDKDGSLLLELQEFKEALPK 161 >1UHK-A nrPDB Length = 191 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 7/61 (11%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 70 KERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLS 129 + + + +++ +++ + + FR+ D D+ G L+ ++++ Sbjct: 111 GDALFDIVD-KDQNGAITLDEW-KAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMT 168 Query: 130 R 130 R Sbjct: 169 R 169 Score = 30.4 bits (67), Expect = 0.45, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 18/61 (29%), Gaps = 9/61 (14%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F I D D +G + ++ + DID G +++ Sbjct: 115 FDIVDKDQNGAITLDEWKAYTKAAGIIQSSED---------CEETFRVCDIDESGQLDVD 165 Query: 172 E 172 E Sbjct: 166 E 166 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 17/123 (13%), Positives = 38/123 (30%), Gaps = 48/123 (39%) Query: 112 FRIFDFDDDGTLNREDL----SRLVNCLTGEGEDT------------------------- 142 F D + +G ++ +++ S +V G + Sbjct: 22 FNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMKYGVETDW 81 Query: 143 --------RLSASEMKQLI-----------DNILEESDIDRDGTINLSEFQHVISRSPDF 183 +L+ E+++ D + + D D++G I L E++ + Sbjct: 82 PAYIEGWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKAAGII 141 Query: 184 ASS 186 SS Sbjct: 142 QSS 144 >2YY5-A nrPDB Length = 348 Score = 31.6 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 40/116 (34%), Gaps = 17/116 (14%) Query: 42 QRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST--------SPAKDSLSFEDFLD 93 + + + + R Q F+ L LP+ N RI +F + +D + Sbjct: 162 ELTRDLAQRIQKKFKLKLRLPQFVQNKDTNRIMDLFDPTKKMSKSSKNQNGVIYLDDPKE 221 Query: 94 LLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSAS 147 ++ AT D K +A + G ++ ++ L E + L+ Sbjct: 222 VVVKKIRQATTDSFNKIRFASKT----QPG---VTNMLTILKALLKEPVNQSLTNQ 270 >6DS2-B nrPDB Length = 114 Score = 31.6 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 23/35 (65%) Query: 145 SASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 ++ +++I++I+E+ D + D ++ EF +++R Sbjct: 51 KENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 >4OKH-A nrPDB Length = 189 Score = 31.2 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Query: 95 LSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLID 154 + + + F+ D D + ++L +++N + + +D + + + Sbjct: 1 MGSSDQESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLK-THGFTLESCR 58 Query: 155 NILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 +++ D D G +NL EF H+ ++ + FK Sbjct: 59 SMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFK 92 Score = 29.7 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 37/121 (30%), Gaps = 31/121 (25%) Query: 79 TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 138 + L+ ++F + K F+ +D D GT+N ++ VN G Sbjct: 65 DTDGSGKLNLQEF----HHLWNKIKAWQKI---FKHYDTDQSGTINSYEMRNAVND-AGF 116 Query: 139 GEDTRLSASEMKQLIDN---------------------ILEESDIDRDG--TINLSEFQH 175 + +L + D D D DG +N+ E+ Sbjct: 117 HLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQ 176 Query: 176 V 176 + Sbjct: 177 L 177 >5HLO-A nrPDB Length = 94 Score = 31.2 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 17/30 (56%) Query: 150 KQLIDNILEESDIDRDGTINLSEFQHVISR 179 K+ D +E DI+ DG +N EF ++ + Sbjct: 49 KKGADVWFKELDINTDGAVNFQEFLILVIK 78 >3SIA-A nrPDB Length = 220 Score = 31.2 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 25/72 (34%), Gaps = 9/72 (12%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D D GTL +L + RLS Q ++ D D +G I+ EF Sbjct: 61 DRDRSGTLEINELM-----MGQFPGGIRLS----PQTALRMMRIFDTDFNGHISFYEFMA 111 Query: 176 VISRSPDFASSF 187 + + F Sbjct: 112 MYKFMELAYNLF 123 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 26/79 (32%), Gaps = 5/79 (6%) Query: 61 LPELKANPFKE--RICRVFS--TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFD 116 P L P + RI + F +L + + +P RIFD Sbjct: 39 FPLLNTIPLDQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALRM-MRIFD 97 Query: 117 FDDDGTLNREDLSRLVNCL 135 D +G ++ + + + Sbjct: 98 TDFNGHISFYEFMAMYKFM 116 >2KGR-A nrPDB Length = 111 Score = 30.8 bits (68), Expect = 0.33, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 26/74 (35%), Gaps = 11/74 (14%) Query: 104 PDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDID 163 +K F D G L ++ + +S + + +I SDID Sbjct: 12 SRLKYRQLFNSHDKTMSGHLTGPQARTIL-----------MQSSLPQAQLASIWNLSDID 60 Query: 164 RDGTINLSEFQHVI 177 +DG + EF + Sbjct: 61 QDGKLTAEEFILAM 74 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 9/63 (14%), Positives = 21/63 (33%) Query: 96 SVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDN 155 ++ ++ P + + + D D DG L E+ ++ + L + I Sbjct: 38 TILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 97 Query: 156 ILE 158 Sbjct: 98 SFR 100 >3DF0-A nrPDB Length = 714 Score = 30.8 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 39/119 (32%), Gaps = 28/119 (23%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + + L ++F L + K +R D D GT+N ++ + + Sbjct: 580 MVDMLDE-DGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKAL 631 Query: 133 N-------CLTGEGEDTRLSASEM-------------KQLIDNILEESDIDRDGTINLS 171 C + R + E+ +++ I ++ D + GTI L Sbjct: 632 EEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLD 690 Score = 29.7 bits (65), Expect = 0.76, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 +D ++ +L ++ + + ED + S + +++ D D G + L EF Sbjct: 544 EDAEISAFELQTILRRVLAKREDIK-SDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 >5HYD-A nrPDB Length = 99 Score = 30.8 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 24/46 (52%) Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + L LS + QL+D I+++ D ++D ++ +EF ++ Sbjct: 34 LKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMV 79 >1F4Q-A nrPDB Length = 165 Score = 30.8 bits (68), Expect = 0.39, Method: Composition-based stats. Identities = 16/116 (13%), Positives = 35/116 (30%), Gaps = 19/116 (16%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + + + F F +L + + F D D GT+ +L + + Sbjct: 45 MIAMLD-RDHTGKMGFNAFKELWAALNA-------WKENFMTVDQDGSGTVEHHELRQAI 96 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 + RLS + ++ ++G I ++ + FK Sbjct: 97 GLM-----GYRLSPQTLTTIVKRY------SKNGRIFFDDYVACCVKLRALTDFFK 141 >1NYA-A nrPDB Length = 176 Score = 30.4 bits (67), Expect = 0.44, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 22/64 (34%), Gaps = 11/64 (17%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D + DG +N ++ + + L K + D + +G ++L E Sbjct: 112 DKNADGQINADEFAAWLTAL-----------GMSKAEAAEAFNQVDTNGNGELSLDELLT 160 Query: 176 VISR 179 + Sbjct: 161 AVRD 164 >5CSF-A nrPDB Length = 95 Score = 30.4 bits (67), Expect = 0.47, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 22/56 (39%) Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSF 187 + L L + ++++D ++E D D DG + EF ++ F Sbjct: 36 LKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEF 91 >4HRG-A nrPDB Length = 115 Score = 30.4 bits (67), Expect = 0.50, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 96 SVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDN 155 S+ S + F F D G L +EDL L + L + +D Sbjct: 1 SMPSQMEHAMETMMFTFHKFAGDK-GYLTKEDLR----VLMEKEFPGFLENQKDPLAVDK 55 Query: 156 ILEESDIDRDGTINLSEFQHVI 177 I+++ D RDG + F +I Sbjct: 56 IMKDLDQCRDGKVGFQSFFSLI 77 >1DJX-A nrPDB Length = 624 Score = 30.4 bits (67), Expect = 0.52, Method: Composition-based stats. Identities = 6/30 (20%), Positives = 16/30 (53%) Query: 149 MKQLIDNILEESDIDRDGTINLSEFQHVIS 178 ++ I + L ++D ++D +N E + + Sbjct: 9 LQHWIHSCLRKADKNKDNKMNFKELKDFLK 38 Score = 28.9 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 34/94 (36%), Gaps = 16/94 (17%) Query: 102 ATPDIKS-HY---AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNIL 157 K H+ R D + D +N ++L + L + ++ + I Sbjct: 3 MDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKEL-----NIQVDDGYAR----KIF 53 Query: 158 EESDIDRDGTINLSE---FQHVISRSPDFASSFK 188 E D + ++ E F ++++ + +F+ Sbjct: 54 RECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFE 87 >4C0K-A nrPDB Length = 423 Score = 30.1 bits (66), Expect = 0.62, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 39/101 (38%), Gaps = 8/101 (7%) Query: 83 KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR--LVNCLTGEGE 140 D+++ + FL L +F + +A G ++ ++ + L L Sbjct: 69 NDAVTLKGFLFLHCLFIQRGRNET--TWAV----LRRFGYNDQLEMCQEYLRPPLKIPPG 122 Query: 141 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 + + +Q + + E D D DG ++ E + + S P Sbjct: 123 SSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFSTCP 163 >4FTG-A nrPDB Length = 96 Score = 30.1 bits (66), Expect = 0.65, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 + F F D G L +EDL L + L + +D I+++ D RD Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLR----VLMEKEFPGFLENQKDPLAVDKIMKDLDQCRD 63 Query: 166 GTINLSEFQHVI 177 G + F +I Sbjct: 64 GKVGFQSFFSLI 75 >5I2U-A nrPDB Length = 332 Score = 30.1 bits (66), Expect = 0.68, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 26/72 (36%), Gaps = 12/72 (16%) Query: 118 DDDGTLNRED-LSRLVNCLTGEGEDTRLSASEMKQLIDNILEE-----------SDIDRD 165 D D L ED + + N + + ++ D + + S+ + D Sbjct: 200 DQDLHLVAEDPIRDVSNIMYTMHFYAATHEAWLRDRTDEAIAKGIPVFVSECGGSEANGD 259 Query: 166 GTINLSEFQHVI 177 G + + E++ + Sbjct: 260 GRLGIEEWKTYV 271 >2JXC-A nrPDB Length = 100 Score = 29.7 bits (65), Expect = 0.71, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 25/54 (46%), Gaps = 11/54 (20%) Query: 120 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 +G L+ + + ++ L++ ++ + E SDID DG ++ EF Sbjct: 28 NGFLSGDKVKPVL-----------LNSKLPVDILGRVWELSDIDHDGMLDRDEF 70 >2MJW-B nrPDB Length = 94 Score = 29.7 bits (65), Expect = 0.76, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 22/46 (47%) Query: 132 VNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 + L + L + + K +D +L++ D + D ++ SEF + Sbjct: 33 LKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFV 78 >1NUB-A nrPDB Length = 229 Score = 29.7 bits (65), Expect = 0.76, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 24/67 (35%), Gaps = 12/67 (17%) Query: 108 SHYAFRIFDFDD-DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 H+ F D DG L+ +L+ L L M+ E D+D D Sbjct: 157 VHWQFGQLDQHPIDGYLSHTELAPLRAPLI-----------PMEHCTTRFFETCDLDNDK 205 Query: 167 TINLSEF 173 I L E+ Sbjct: 206 YIALDEW 212 >4YBH-B nrPDB Length = 92 Score = 29.3 bits (64), Expect = 0.92, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 27/64 (42%), Gaps = 6/64 (9%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 181 TL++++L L+ G + + I ++E+ D ++D +N E+ + Sbjct: 30 TLSKKELKELIQKELTIGSKLQDAE------IARLMEDLDRNKDQEVNFQEYVTFLGALA 83 Query: 182 DFAS 185 + Sbjct: 84 LIYN 87 >2MHH-A nrPDB Length = 96 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 78 STSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTG 137 + + A L F+++ L D F +D D D L+ E+ ++ + L G Sbjct: 27 ADANADQHLDFDEWRQEL---KCRGHADADIEAVFAKYDVDGDRVLDAEEQMKMAHDLEG 83 Query: 138 EGEDTRLSASEMK 150 + D +E++ Sbjct: 84 QKSDLNNQLAELE 96 >3I5J-B nrPDB Length = 327 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 4/57 (7%), Positives = 20/57 (35%) Query: 27 ILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAK 83 + L ++++ P + + ++ + +L + + + + F+ Sbjct: 51 MNLWYKQYRNASPLKHDNWDAFTDPDQLVYRTYNLMQDGQESYVQSLFDQFNEREHD 107 >2JQ6-A nrPDB Length = 139 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 25/55 (45%), Gaps = 5/55 (9%) Query: 124 NREDLSRLVNCLTGEGEDTRLSASEMKQ-----LIDNILEESDIDRDGTINLSEF 173 +++ ++ + G+ +K ++ I + +D+D+DG ++ EF Sbjct: 52 TYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >2Y3N-B nrPDB Length = 71 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 22/57 (38%), Gaps = 12/57 (21%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSE 172 D + DG +N D+ L + ++ ++D++ DG IN + Sbjct: 8 DLNGDGVINMADVMILAQSFGKAIGNPGVNE------------KADLNNDGVINSDD 52 >4U3S-B nrPDB Length = 184 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%), Gaps = 13/68 (19%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 DG +N ED+ + D + D++RDG I+L + +++ Sbjct: 128 QDGAINLEDILEICKAFGTSSTDAKYQVG------------LDLNRDGAISLED-VMIVA 174 Query: 179 RSPDFASS 186 + + SS Sbjct: 175 KHFNKVSS 182 >2KFH-A nrPDB Length = 105 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 25/55 (45%), Gaps = 5/55 (9%) Query: 124 NREDLSRLVNCLTGEGEDTRLSASEMKQ-----LIDNILEESDIDRDGTINLSEF 173 +++ ++ + G+ +K ++ I + +D+D+DG ++ EF Sbjct: 18 TYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >5KU1-A nrPDB Length = 424 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 22/43 (51%), Gaps = 3/43 (6%) Query: 151 QLIDNILEESDIDRDGTINLSE---FQHVISRSPDFASSFKIV 190 + + I + SD D DGT+N +E FQ + +P + + V Sbjct: 11 KALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDV 53 >1KFU-L nrPDB Length = 699 Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 36/116 (31%), Gaps = 18/116 (15%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132 + + S L ++F L + K +R D D GT+N ++ + + Sbjct: 579 MVDMLD-SDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKAL 630 Query: 133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFK 188 E ++ + ++ D I+ F + R FK Sbjct: 631 -----EEAGFKMPCQLHQVIVARF-----ADDQLIIDFDNFVRCLVRLETLFKIFK 676 >4XZE-A nrPDB Length = 488 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 21/165 (12%), Positives = 54/165 (32%), Gaps = 29/165 (17%) Query: 23 TKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPA 82 TK+E +++F E + ES+ +P+L +K + + A Sbjct: 12 TKEEFNTWYKQFAEKHKLNNKYTESASFCAE-------IPQLDTYKYKMELASTDNERDA 64 Query: 83 KDSLSFEDFLDLLSVFSD------TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLT 136 S + + + + T T + FD + D D ++ + Sbjct: 65 IYSSALIEATRFCAPIMECAWASCTGTVKRGLEW----FDKNKD-----SDTVKVWDA-- 113 Query: 137 GEGEDTRLSASEMKQLIDNILEESDID--RDGTINLSEFQHVISR 179 +L +++ ++ +D ++ E+ ++ + Sbjct: 114 ---NYQKLRTETPPAEALLAYQKAALNWRKDVGFSIGEYTSILKK 155 >2Y5I-A nrPDB Length = 99 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 L++ +L L+N E D +S + L++ I+ + D ++D ++ +EF ++ Sbjct: 28 KLSKGELKELLNA---ELTDFLMSQKDPM-LVEKIMNDLDSNKDNEVDFNEFVVLV 79 >5X2E-A nrPDB Length = 80 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 22/70 (31%), Gaps = 11/70 (15%) Query: 112 FRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLS 171 F D D ++ +L E + +++ + D D G+I L Sbjct: 7 FVSIDKDGTNVISYPEL-----------EQYVAENNLDPSMVEKWKQLFDPDNTGSITLE 55 Query: 172 EFQHVISRSP 181 F + P Sbjct: 56 TFCSKLGLKP 65 Score = 26.2 bits (56), Expect = 8.2, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 21/54 (38%), Gaps = 4/54 (7%) Query: 73 ICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE 126 I + +S+ + ++ + + K ++FD D+ G++ E Sbjct: 6 IFVSID-KDGTNVISYPELEQYVAENNLDPSMVEKWK---QLFDPDNTGSITLE 55 >5COV-A nrPDB Length = 340 Score = 28.1 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 22/64 (34%), Gaps = 8/64 (12%) Query: 106 IKSH----YAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTR----LSASEMKQLIDNIL 157 K Y F I+D D L + LV L G + L E+ + IL Sbjct: 239 EKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQIL 298 Query: 158 EESD 161 +D Sbjct: 299 AMAD 302 >1SNL-A nrPDB Length = 103 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 33/77 (42%), Gaps = 7/77 (9%) Query: 112 FRIFDFDDDGTLNREDL-------SRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDR 164 F + D + DG L+ ++L V E +D R E ++ +++++ D ++ Sbjct: 26 FILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQ 85 Query: 165 DGTINLSEFQHVISRSP 181 D + L EF R Sbjct: 86 DRLVTLEEFLASTQRKE 102 >4WI0-B nrPDB Length = 156 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 13/68 (19%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 178 DG +N ED+ + D + D++RDG I+L + +++ Sbjct: 100 QDGAINLEDILEICKAFNTSSTDAKYQVG------------LDLNRDGAISLED-VMIVA 146 Query: 179 RSPDFASS 186 + SS Sbjct: 147 KHFGKVSS 154 >3BSH-A nrPDB Length = 414 Score = 27.4 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 14/27 (51%) Query: 113 RIFDFDDDGTLNREDLSRLVNCLTGEG 139 R++D D N +L L+ L G+G Sbjct: 56 RLYDIDASKYGNAAELKSLIGALHGKG 82 >2KLD-A nrPDB Length = 123 Score = 27.4 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 25/69 (36%), Gaps = 3/69 (4%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 L+F++ L D + F +D D D L + ++ + L E E Sbjct: 58 QGGGKLNFDELRQDL---KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERE 114 Query: 141 DTRLSASEM 149 D L S + Sbjct: 115 DLDLDHSSL 123 >4PCW-A nrPDB Length = 94 Score = 27.4 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 19/36 (52%) Query: 144 LSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 179 L + ++D ++ DID + I+ +EF ++ + Sbjct: 47 LKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFK 82 >5NRM-B nrPDB Length = 66 Score = 27.4 bits (59), Expect = 4.2, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 9/58 (15%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 D D +G++N D + + N L G +D ++ D++ D +IN+++F Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDD---------IKAGDLNGDKSININDF 52 >1SRA-A nrPDB Length = 151 Score = 27.4 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 24/67 (35%), Gaps = 12/67 (17%) Query: 108 SHYAFRIFDFDD-DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDG 166 H+ F D DG L+ +L+ L L M+ E D+D D Sbjct: 79 VHWQFGQLDQHPIDGYLSHTELAPLRAPLI-----------PMEHCTTRFFETCDLDNDK 127 Query: 167 TINLSEF 173 I L E+ Sbjct: 128 YIALDEW 134 >5VP3-A nrPDB Length = 206 Score = 27.0 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 9/70 (12%), Positives = 24/70 (34%) Query: 106 IKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRD 165 + + F FD D DG + +++ + + T +M+ + +D Sbjct: 34 ERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPV 93 Query: 166 GTINLSEFQH 175 + ++ Sbjct: 94 NGLKREDWVE 103 >1KFX-S nrPDB Length = 184 Score = 27.0 bits (58), Expect = 5.6, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 23/56 (41%), Gaps = 1/56 (1%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 DD ++ +L ++N + D + + +++ D D G + EF+ Sbjct: 27 DDMEVSATELMNILNKVVTRHPDLK-TDGFGIDTCRSMVAVMDSDTTGKLGFEEFK 81 >3BOW-B nrPDB Length = 184 Score = 26.6 bits (57), Expect = 6.1, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 23/56 (41%), Gaps = 1/56 (1%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 DD ++ +L ++N + D + + +++ D D G + EF+ Sbjct: 27 DDMEVSATELMNILNKVVTRHPDLK-TDGFGIDTCRSMVAVMDSDTTGKLGFEEFK 81 >2JTT-A nrPDB Length = 90 Score = 26.6 bits (57), Expect = 6.1, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 30/56 (53%), Gaps = 6/56 (10%) Query: 122 TLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 177 TL++++L L+ G +L +E+ +L+D++ D ++D +N E+ + Sbjct: 28 TLSKKELKELIQKELTIGS--KLQDAEIVKLMDDL----DRNKDQEVNFQEYITFL 77 >2KQ6-A nrPDB Length = 78 Score = 26.6 bits (57), Expect = 7.0, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 3/70 (4%) Query: 81 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 140 L+F++ L D + F +D D D L + ++ + L E E Sbjct: 12 QGGGKLNFDELRQDL---KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERE 68 Query: 141 DTRLSASEMK 150 D L S + Sbjct: 69 DLDLDHSSLP 78 >1WY9-A nrPDB Length = 147 Score = 26.6 bits (57), Expect = 7.0, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 32/84 (38%), Gaps = 14/84 (16%) Query: 98 FSDTATPDIKSHYAFRI----FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLI 153 +S+ K AF++ FD + +G ++ L R++ L L Sbjct: 37 YSNDEDLPSKLE-AFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELK-------- 87 Query: 154 DNILEESDIDRDGTINLSEFQHVI 177 ++ E + T + S+F ++ Sbjct: 88 -RLIREVSSGSEETFSYSDFLRMM 110 >5NRK-B nrPDB Length = 68 Score = 26.6 bits (57), Expect = 7.3, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 26/58 (44%), Gaps = 9/58 (15%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 173 D D +G++N D + + N L G +D ++ D++ D +IN +F Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDD---------IKAGDLNGDKSINSLDF 52 >5MVF-A nrPDB Length = 523 Score = 26.6 bits (57), Expect = 7.3, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 21/53 (39%), Gaps = 5/53 (9%) Query: 126 EDLSRLVNCLTGEGEDTRLSASE-----MKQLIDNILEESDIDRDGTINLSEF 173 ++L ++ + G+ ++ I + +D D DG ++ EF Sbjct: 434 DELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEF 486 >5LXV-B nrPDB Length = 88 Score = 26.2 bits (56), Expect = 8.0, Method: Composition-based stats. Identities = 12/76 (15%), Positives = 26/76 (34%), Gaps = 18/76 (23%) Query: 116 DFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175 D D DG ++ DL + + E +D++ DG I+ + Sbjct: 27 DLDGDGEVDVFDLILMRKAVENGDT--------------ERFEAADLNCDGVIDSDD--- 69 Query: 176 VISRSPDFASSFKIVL 191 ++ ++ + L Sbjct: 70 -LTYHSEYLHGIRKTL 84 >1NP8-A nrPDB Length = 159 Score = 26.2 bits (56), Expect = 8.6, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 23/56 (41%), Gaps = 1/56 (1%) Query: 119 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 174 DD ++ +L ++N + D + + +++ D D G + EF+ Sbjct: 23 DDMEVSATELMNILNKVVTRHPDLK-TDGFGIDTCRSMVAVMDSDTTGKLGFEEFK 77 >1K1D-A nrPDB Length = 460 Score = 26.2 bits (56), Expect = 9.4, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 26/78 (33%), Gaps = 10/78 (12%) Query: 28 LLAHRRFC-ELLPQEQRSVESSLRAQVPFE--------QILSLPELKANPFKERICRVFS 78 H+ L Q S + F+ +P ++R+ +FS Sbjct: 293 EKWHQEVLWNALKNGQLQTLGSDQCSFDFKGQKELGRGDFTKIPNGGP-IIEDRVSILFS 351 Query: 79 TSPAKDSLSFEDFLDLLS 96 K ++ F+D++S Sbjct: 352 EGVKKGRITLNQFVDIVS 369 >1FI6-A nrPDB Length = 92 Score = 26.2 bits (56), Expect = 9.5, Method: Composition-based stats. Identities = 10/19 (52%), Positives = 12/19 (63%) Query: 156 ILEESDIDRDGTINLSEFQ 174 I E SD D+DG + L EF Sbjct: 48 IWELSDFDKDGALTLDEFC 66 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.131 0.333 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,502,781 Number of Sequences: 36641 Number of extensions: 225009 Number of successful extensions: 2657 Number of sequences better than 10.0: 325 Number of HSP's better than 10.0 without gapping: 359 Number of HSP's successfully gapped in prelim test: 149 Number of HSP's that attempted gapping in prelim test: 1073 Number of HSP's gapped (non-prelim): 941 length of query: 191 length of database: 10,336,785 effective HSP length: 92 effective length of query: 99 effective length of database: 6,965,813 effective search space: 689615487 effective search space used: 689615487 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 56 (26.2 bits)