BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q99714 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2O23-A nrPDB 524 e-149 1E3W-A nrPDB 462 e-131 3PPI-A nrPDB 200 4e-52 4NBV-A nrPDB 130 6e-31 2HQ1-A nrPDB 127 4e-30 4NBT-A nrPDB 120 8e-28 3RSH-A nrPDB 118 2e-27 4CQL-A nrPDB 118 2e-27 4CQM-B nrPDB 115 1e-26 5CDY-A nrPDB 113 6e-26 5T5Q-A nrPDB 113 8e-26 4JRO-A nrPDB 111 3e-25 4DMM-A nrPDB 110 8e-25 5ITV-A nrPDB 109 1e-24 3VZS-A nrPDB 109 1e-24 1NFF-A nrPDB 108 2e-24 2PNF-A nrPDB 108 3e-24 3EZL-A nrPDB 107 4e-24 2UVD-A nrPDB 107 5e-24 2CFC-A nrPDB 105 1e-23 4KMS-A nrPDB 104 3e-23 2HSD-A nrPDB 103 7e-23 4RZH-A nrPDB 102 2e-22 1Q7C-A nrPDB 102 2e-22 3WOH-A nrPDB 101 3e-22 2CDH-G nrPDB 100 5e-22 1HXH-A nrPDB 100 1e-21 5IZ4-A nrPDB 98 3e-21 4K6F-A nrPDB 97 5e-21 3OSU-A nrPDB 97 6e-21 3FTP-A nrPDB 97 7e-21 1GEE-A nrPDB 97 1e-20 2C07-A nrPDB 96 2e-20 4IS3-A nrPDB 96 2e-20 4RZI-B nrPDB 95 3e-20 3AUT-A nrPDB 95 4e-20 5JS6-A nrPDB 93 9e-20 3F9I-A nrPDB 92 3e-19 3EMK-A nrPDB 91 5e-19 2Q2Q-A nrPDB 90 1e-18 1UZM-A nrPDB 89 1e-18 4M8S-A nrPDB 89 2e-18 3WTC-A nrPDB 88 3e-18 5VT6-A nrPDB 88 4e-18 1GEG-A nrPDB 88 4e-18 2GDZ-A nrPDB 88 5e-18 3V2H-A nrPDB 87 7e-18 3RWB-A nrPDB 86 1e-17 5OJG-A nrPDB 86 2e-17 2NM0-A nrPDB 84 4e-17 2BGM-A nrPDB 84 5e-17 3OEC-A nrPDB 84 5e-17 5ILO-A nrPDB 84 6e-17 4FC7-A nrPDB 84 7e-17 4DBZ-A nrPDB 84 8e-17 3U5T-A nrPDB 84 8e-17 4BO1-A nrPDB 83 1e-16 3LYL-A nrPDB 82 2e-16 2PH3-A nrPDB 82 3e-16 5OVJ-A nrPDB 82 3e-16 2EW8-A nrPDB 81 4e-16 5OVL-A nrPDB 81 4e-16 3GRP-A nrPDB 80 1e-15 5YSS-A nrPDB 79 2e-15 1AE1-A nrPDB 78 4e-15 4TRR-A nrPDB 77 6e-15 4IIN-A nrPDB 77 6e-15 4AVY-A nrPDB 77 7e-15 1K2W-A nrPDB 77 8e-15 5U9P-A nrPDB 77 1e-14 3V2G-A nrPDB 76 1e-14 3A28-C nrPDB 76 2e-14 3WYE-A nrPDB 74 6e-14 1AHH-A nrPDB 74 6e-14 4MOW-A nrPDB 73 1e-13 2AE2-A nrPDB 72 2e-13 3ZV3-A nrPDB 72 2e-13 4Z9Y-A nrPDB 72 3e-13 3R3S-A nrPDB 71 4e-13 4E6P-A nrPDB 71 6e-13 3T7C-A nrPDB 71 6e-13 1X1T-A nrPDB 70 6e-13 5B1Y-A nrPDB 70 7e-13 5O3Z-A nrPDB 70 1e-12 2B4Q-A nrPDB 70 1e-12 6CI9-A nrPDB 69 2e-12 5EJ2-A nrPDB 69 2e-12 1BDB-A nrPDB 69 3e-12 4CR6-A nrPDB 68 3e-12 3UVE-A nrPDB 68 5e-12 1H5Q-A nrPDB 66 2e-11 4DA9-A nrPDB 66 2e-11 3UN1-A nrPDB 65 2e-11 5JY1-A nrPDB 65 4e-11 4HP8-A nrPDB 65 4e-11 3W8F-A nrPDB 64 5e-11 4RGB-A nrPDB 64 6e-11 1DOH-A nrPDB 64 8e-11 6NRP-A nrPDB 63 1e-10 4IIV-A nrPDB 63 2e-10 3UF0-A nrPDB 62 2e-10 1CYD-A nrPDB 62 2e-10 3O4R-A nrPDB 62 3e-10 2ZAT-A nrPDB 62 3e-10 2FWM-X nrPDB 61 4e-10 3OML-A nrPDB 59 2e-09 2QHX-A nrPDB 59 2e-09 2BFA-A nrPDB 59 2e-09 1B15-A nrPDB 58 5e-09 4GKB-A nrPDB 57 6e-09 4HBG-A nrPDB 57 6e-09 3D3W-A nrPDB 57 8e-09 3PXX-A nrPDB 55 2e-08 3RKU-A nrPDB 55 4e-08 1MG5-A nrPDB 54 6e-08 1YXM-A nrPDB 54 6e-08 2X9N-A nrPDB 54 7e-08 2NWQ-A nrPDB 52 2e-07 3GDF-A nrPDB 52 3e-07 1P33-A nrPDB 51 5e-07 2AG5-A nrPDB 50 7e-07 3O26-A nrPDB 47 6e-06 6CGE-A nrPDB 47 7e-06 1A27-A nrPDB 47 7e-06 1O5I-A nrPDB 46 1e-05 3V8B-A nrPDB 46 1e-05 4EGF-A nrPDB 44 6e-05 3U9L-A nrPDB 44 7e-05 3OIC-A nrPDB 44 8e-05 5LCX-A nrPDB 42 4e-04 4DRY-A nrPDB 41 5e-04 2DKN-A nrPDB 40 0.001 1FJH-A nrPDB 39 0.002 3KZV-A nrPDB 38 0.005 3E9N-A nrPDB 38 0.006 5L51-A nrPDB 37 0.010 1N5D-A nrPDB 37 0.012 3UCF-A nrPDB 37 0.012 3BHI-A nrPDB 35 0.046 2HRB-A nrPDB 34 0.070 1W73-A nrPDB 34 0.077 3U4C-A nrPDB 33 0.17 2YW9-A nrPDB 32 0.30 1YQG-A nrPDB 31 0.45 4EJ6-A nrPDB 30 1.1 4RQU-A nrPDB 29 1.8 3IP1-A nrPDB 29 2.4 4Z3K-A nrPDB 28 3.7 4HWK-A nrPDB 28 4.0 1OAA-A nrPDB 28 4.3 4LN1-A nrPDB 27 7.3 1LU9-A nrPDB 27 9.3 2EFY-A nrPDB 27 9.5 >2O23-A nrPDB Length = 265 Score = 524 bits (1349), Expect = e-149, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF Sbjct: 3 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 62 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV Sbjct: 63 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 122 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 123 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 182 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI Sbjct: 183 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 242 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 243 IENPFLNGEVIRLDGAIRMQP 263 >1E3W-A nrPDB Length = 261 Score = 462 bits (1188), Expect = e-131, Method: Compositional matrix adjust. Identities = 228/261 (87%), Positives = 245/261 (93%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 MAAA RSVKGLVAVITGGASGLGL+TA+RLVGQGA+AVLLD+PNS GE +AKKLG NC+F Sbjct: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 APA+VTSEK+VQ AL LAK KFGR+DVAVNCAGIAVA KTY+ KK Q HTLEDFQRV++V Sbjct: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL+GTFNVIRLVAG MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 PIARDLAPIGIRV+TIAPGLF TPLLT+LP+ V NFLASQVPFPSRLGDPAEYAHLVQ + Sbjct: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 241 IENPFLNGEVIRLDGAIRMQP 261 >3PPI-A nrPDB Length = 281 Score = 200 bits (509), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 109/258 (42%), Positives = 155/258 (60%), Gaps = 3/258 (1%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + +G A+++GGA GLG AT RL G V+ DL G+A A +LGN F + Sbjct: 25 IKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTN 84 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNC-AGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 VTSE V A+ A + GR+ AV G VA + + G + F + +D+ L Sbjct: 85 VTSEDSVLAAIEAAN-QLGRLRYAVVAHGGFGVAQRIVQ-RDGSPADMGGFTKTIDLYLN 142 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GT+NV RLVA + EP + G+RG ++ TAS+A +EGQ+GQ AY+A+K G++G+T+ A Sbjct: 143 GTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAA 202 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 RDL+ GIRV TIAPG TP++ S+ E+ A+ +PFP RLG P E+A ++ N Sbjct: 203 RDLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFADAAAFLLTN 262 Query: 244 PFLNGEVIRLDGAIRMQP 261 ++NGEV+RLDGA R P Sbjct: 263 GYINGEVMRLDGAQRFTP 280 >4NBV-A nrPDB Length = 246 Score = 130 bits (327), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 91/257 (35%), Positives = 134/257 (52%), Gaps = 18/257 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---D 64 ++G VA+ITG A+G+G ATA+R GA VL D+ + A +L A D Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRVD 62 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 VT +V +A RVD+ VN AGI ++ + + Q F V+DVNL G Sbjct: 63 VTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQ------FDAVIDVNLKG 116 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 FN + VAG M +QG +GVI+N +SV G GQ Y+ASK G++G T AR Sbjct: 117 VFNCAQAVAGLM----TEQG--KGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWAR 170 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN- 243 +L P G+RV + PG T +L ++P+KV + + S + RL +PAE A + + + Sbjct: 171 ELGPKGVRVNAVCPGFVNTEILQTVPDKVLDGMTSSC-WLRRLAEPAEIASIYAFLASDD 229 Query: 244 -PFLNGEVIRLDGAIRM 259 ++NG I G + + Sbjct: 230 ASYVNGVAIEASGGMSL 246 >2HQ1-A nrPDB Length = 247 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 91/258 (35%), Positives = 136/258 (52%), Gaps = 19/258 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG-EAQAKKL---GNNCVFAPA 63 +KG A++TG + GLG A A +L GA+ VL P S +A A++ G N V A Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKG 62 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV + +DV+ + A FGR+D+ VN AGI T LK + +D+ VL+ NL Sbjct: 63 DVKNPEDVENMVKTAMDAFGRIDILVNNAGIT--RDTLMLKMSE----KDWDDVLNTNLK 116 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + V+ M + + G IIN S+A G GQA Y+ASK G++G T IA Sbjct: 117 SAYLCTKAVSKIMLKQ------KSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIA 170 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLV--QAII 241 ++ A GI +APG+ T + LP+KV + +P R G P E A++V A Sbjct: 171 KEFAAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPLK-RFGTPEEVANVVGFLASD 229 Query: 242 ENPFLNGEVIRLDGAIRM 259 ++ ++ G+VI +DG + M Sbjct: 230 DSNYITGQVINIDGGLVM 247 >4NBT-A nrPDB Length = 240 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 91/267 (34%), Positives = 137/267 (51%), Gaps = 39/267 (14%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------PNSGGEAQAKKLGNN 57 + ++G VAVITGGA GLG A A +GA + DL PN G Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEG---------- 50 Query: 58 CVFAPADVTS-EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQR 116 DVT EK Q+ + K+G++D+ VN AGI + T + + Q + Sbjct: 51 MYLNVTDVTGVEKFYQSVI----DKYGKIDILVNNAGITKDAMTRKMTEAQ------WDA 100 Query: 117 VLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 V+DVNL G FN+ RLV +M Q G IIN +SV G +GQA Y+A+K G++ Sbjct: 101 VIDVNLKGVFNLTRLVGPQM------QTNGYGSIINISSVVGVFGNIGQANYAATKAGVI 154 Query: 177 GMTLPIARDLAPIG--IRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYA 234 G+T+ A++ A G +RV IAPG T +L ++P+ + + A+ + +RLG P E A Sbjct: 155 GLTMTWAKEFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAA-LTMLNRLGQPEEIA 213 Query: 235 H--LVQAIIENPFLNGEVIRLDGAIRM 259 L A + ++ G+ I ++G +R+ Sbjct: 214 KVALFLASDDASYVTGQTINVNGGMRL 240 >3RSH-A nrPDB Length = 251 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 82/256 (32%), Positives = 136/256 (53%), Gaps = 17/256 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 +++G VA++TG + G+G A AE L +GA + SG +A + LG+N +VT Sbjct: 9 NLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVT 68 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + + ++ L +FG VD+ VN AGI + +K+ E++ +++ NL F Sbjct: 69 NPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKE------EEWSDIMETNLTSIF 122 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + ++G IIN SV G GQA Y+A+K G++G T +AR++ Sbjct: 123 RLSKAVLRGMMKK------RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREV 176 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP-- 244 A G+ V T+APG T + +L ++ +QVP RLGDP E A V A + +P Sbjct: 177 ASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVP-AGRLGDPREIASAV-AFLASPEA 234 Query: 245 -FLNGEVIRLDGAIRM 259 ++ GE + ++G + M Sbjct: 235 AYITGETLHVNGGMYM 250 >4CQL-A nrPDB Length = 261 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 83/266 (31%), Positives = 134/266 (50%), Gaps = 27/266 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG-----------N 56 ++ +A++TG SG+G A + RL G+GA+ DL + + + LG N Sbjct: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 Query: 57 NCVFAPADVTSEKDVQTALALAKGKFGRV-DVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 + F ADV+ + + L + F R V V+CAGI ++ + +D+ Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE------DDWD 121 Query: 116 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 +V+ VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G+ Sbjct: 122 KVIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGV 176 Query: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAH 235 +G+T AR+L GIR ++ PG TP+ +P+KV + + +P LGDP + A Sbjct: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVAD 235 Query: 236 LVQ--AIIENPFLNGEVIRLDGAIRM 259 +V A ++ ++ G + + G + M Sbjct: 236 VVAFLASEDSGYITGTSVEVTGGLFM 261 >4CQM-B nrPDB Length = 244 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 124/248 (50%), Gaps = 16/248 (6%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 V + GG+ G+G A A+ + +G ++ G +A A LG + + DV E DV Sbjct: 11 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 70 Query: 72 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 Q + GRV+ VN AGI ++ L + +T ED L NL+G+ + Sbjct: 71 QNTFEELEKHLGRVNFLVNAAGI---NRDGLLVRTKT---EDMVSQLHTNLLGSMLTCKA 124 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A I Sbjct: 125 AMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 178 Query: 192 RVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVI 251 RV +APG T + L E+ L +P R G+ E AH V ++E+P++ G V+ Sbjct: 179 RVNVVAPGFVHTDMTKDLKEE---HLKKNIPL-GRFGETIEVAHAVVFLLESPYITGHVL 234 Query: 252 RLDGAIRM 259 +DG +++ Sbjct: 235 VVDGGLQL 242 >5CDY-A nrPDB Length = 244 Score = 113 bits (283), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 81/255 (31%), Positives = 128/255 (50%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 S +G +A++TG + G+G A AE LV +GA + G EA + LG N +V Sbjct: 2 SFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVV 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + T LA + +FG VD+ VN AGI + +K +++Q ++D NL F Sbjct: 62 DPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKD------DEWQDIIDTNLTSVF 115 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + + G II SV G GQ Y+A+K G++G + +AR++ Sbjct: 116 RLSKAVMRAMMKK------RFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREV 169 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ--AIIENP 244 A GI V +APG T + +L + + +QVP +RLGD E A V A E Sbjct: 170 ASRGITVNVVAPGFIETDMTRTLTDDQRAGILAQVP-ANRLGDAKEIASAVAFLASDEAS 228 Query: 245 FLNGEVIRLDGAIRM 259 +++GE + ++G + M Sbjct: 229 YISGETLHVNGGMYM 243 >5T5Q-A nrPDB Length = 247 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 84/251 (33%), Positives = 128/251 (50%), Gaps = 22/251 (8%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA--PADVTSEKDV 71 V+TG G+G A AE GA+ VL DL G +A A LG+ A AD +S D Sbjct: 13 VLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSADDA 72 Query: 72 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 + +ALA +FG +D V AGI Y K + D+ R + +NL G F + + Sbjct: 73 EKTVALAMERFGGIDFLVPSAGI------YQAKPFAEMSDADWHRTISINLDGVFYLCKR 126 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 + ++ I+ AS+AA+ G A Y A+KG +V MT ++R+LAP Sbjct: 127 ALPALKEDSS--------IVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAP-KT 177 Query: 192 RVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP---FLNG 248 RV ++PG+ TP+ + L + + +Q P RLG P+E A ++ A + +P F+ G Sbjct: 178 RVNGVSPGIIETPMTSELLKTRMDETMTQTPL-KRLGKPSEIASVI-AFLCSPAASFVTG 235 Query: 249 EVIRLDGAIRM 259 E I+++G I M Sbjct: 236 ETIQVNGGIYM 246 >4JRO-A nrPDB Length = 271 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 86/261 (32%), Positives = 134/261 (51%), Gaps = 23/261 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNS--GGEAQAKKLGNNCVFA--- 61 +++G VAV+TGG+ G+G A L +GA+ + + S E AK + + V Sbjct: 26 TLQGKVAVVTGGSRGIGRDIAINLAKEGAN-IFFNYNGSPEAAEETAKLVAEHGVEVEAM 84 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 A+V +DV A +FGRVD+ VN AGI + +K+ +++ V+++N Sbjct: 85 KANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKE------DEWDDVININ 138 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQR-GVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 L GTF + V+ M + QR G IIN ASV G GQA Y ASK G++G+T Sbjct: 139 LKGTFLCTKAVSRTMMK-------QRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTK 191 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 AR+LAP GI V +APG T + L EK + +Q+P + G + A+ V + Sbjct: 192 TTARELAPRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQIPLGA-YGTTEDIANAVLFL 250 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + ++ G+ + +DG + M Sbjct: 251 ASDASKYITGQTLSVDGGMVM 271 >4DMM-A nrPDB Length = 269 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 87/257 (33%), Positives = 131/257 (50%), Gaps = 27/257 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA-----PADVT 66 +A++TG + G+G A A L GA V ++ +S G A ADV+ Sbjct: 30 IALVTGASRGIGRAIALELAAAGAK-VAVNYASSAGAADEVVAAIAAAGGEAFAVKADVS 88 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E +V+ A ++GR+DV VN AGI + +K+ +D+Q VLD+NL G F Sbjct: 89 QESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKR------DDWQSVLDLNLGGVF 142 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R A M + + G IIN ASV G GQA YSA+K G++G+T +A++L Sbjct: 143 LCSRAAAKIMLKQ------RSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKEL 196 Query: 187 APIGIRVMTIAPGLFGTPLLTSL-PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP- 244 A GI V +APG T + + L EK+ +P R G+ AE A +V+ + +P Sbjct: 197 ASRGITVNAVAPGFIATDMTSELAAEKLLEV----IPL-GRYGEAAEVAGVVRFLAADPA 251 Query: 245 --FLNGEVIRLDGAIRM 259 ++ G+VI +DG + M Sbjct: 252 AAYITGQVINIDGGLVM 268 >5ITV-A nrPDB Length = 255 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 84/258 (32%), Positives = 125/258 (48%), Gaps = 24/258 (9%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV-FAPADVTSEKDVQ 72 +ITGGASG+G A + +GQ A+ V+ D+ + GEA +K N+ + F D+T E Q Sbjct: 11 LITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEAACQ 70 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV 132 A+ A FG +DV +N AGI + + + ++ L D+ +VL VNL G F + + Sbjct: 71 HAVESAVHTFGGLDVLINNAGIEIVAPIHEME------LSDWNKVLQVNLTGMFLMSKHA 124 Query: 133 AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 M +G IINT SV AY+ASKGG++ +T +A D A IR Sbjct: 125 LKHM------LAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 178 Query: 193 VMTIAPGLFGTPLLTS--------LPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN- 243 V + PG+ TPL E++ A P RLG P E A+++ + + Sbjct: 179 VNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLL-RLGKPEEIANVMLFLASDL 237 Query: 244 -PFLNGEVIRLDGAIRMQ 260 ++ G I DG Q Sbjct: 238 SSYMTGSAITADGGYTAQ 255 >3VZS-A nrPDB Length = 257 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/254 (31%), Positives = 126/254 (49%), Gaps = 19/254 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNS----GGEAQAKKLGNNCVFAPADVTS 67 +A +TGG G+G A +RL G V PNS Q K LG + + + +V Sbjct: 16 IAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVAD 75 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 +TA K + G VDV +N AGI ++ +K T D+ V+D NL FN Sbjct: 76 WDSTKTAFDKVKSEVGEVDVLINNAGI---TRDVVFRK---MTRADWDAVIDTNLTSLFN 129 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V + V M D+G R I+N +SV +GQ GQ YS +K G+ G T+ +A+++A Sbjct: 130 VTKQVIDGM----ADRGWGR--IVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVA 183 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENPF 245 G+ V T++PG T ++ ++ + V + + + +P RLG P E A + + E+ F Sbjct: 184 TKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVK-RLGLPEEIASICAWLSSEESGF 242 Query: 246 LNGEVIRLDGAIRM 259 G L+G + M Sbjct: 243 STGADFSLNGGLHM 256 >1NFF-A nrPDB Length = 260 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 84/253 (33%), Positives = 128/253 (50%), Gaps = 26/253 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G VA+++GGA G+G + +V +GA V D+ + G+A A +L + + DVT Sbjct: 5 LTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVTQ 64 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + A+ A FG + V VN AGI N+ + + L ++QR+LDVNL G F Sbjct: 65 PAQWKAAVDTAVTAFGGLHVLVNNAGI------LNIGTIEDYALTEWQRILDVNLTGVFL 118 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 IR V +P + RG IIN +S+ G V Y+A+K + G+T A +L Sbjct: 119 GIRAVV------KPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELG 172 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG---DPAEYAHLVQAII--E 242 P GIRV +I PGL TP+ +PE + F + LG +P E ++LV + E Sbjct: 173 PSGIRVNSIHPGLVKTPMTDWVPEDI---------FQTALGRAAEPVEVSNLVVYLASDE 223 Query: 243 NPFLNGEVIRLDG 255 + + G +DG Sbjct: 224 SSYSTGAEFVVDG 236 >2PNF-A nrPDB Length = 248 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 75/256 (29%), Positives = 126/256 (49%), Gaps = 19/256 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF----APA 63 ++G V+++TG G+G A AE+L G++ ++ +A A+++ N Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEM 64 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 ++ SE+ + A +D+ VN AGI + +L D++ VL VNL Sbjct: 65 NLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRM------SLLDWEEVLKVNLT 118 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GTF V + +M + + G I+N +SV F G VGQ YS +K G++G T +A Sbjct: 119 GTFLVTQNSLRKMIKQ------RWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLA 172 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 ++LAP + V +APG T + L E++ Q+P R G P E A++V + Sbjct: 173 KELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPL-GRFGSPEEVANVVLFLCSE 231 Query: 244 --PFLNGEVIRLDGAI 257 ++ GEVI ++G + Sbjct: 232 LASYITGEVIHVNGGM 247 >3EZL-A nrPDB Length = 256 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 82/254 (32%), Positives = 125/254 (49%), Gaps = 19/254 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA----KKLGNNCVFAPADVTS 67 +A +TGG G+G + +RL G V PNS + K LG + + +V Sbjct: 15 IAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGD 74 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + A K + G +DV VN AGI ++ +K T ED+Q V+D NL FN Sbjct: 75 WDSTKQAFDKVKAEVGEIDVLVNNAGI---TRDVVFRK---MTREDWQAVIDTNLTSLFN 128 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V + V M ++G R IIN +SV +GQ GQ YS +K GI G T+ +A+++A Sbjct: 129 VTKQVIDGM----VERGWGR--IINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVA 182 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENPF 245 G+ V T++PG GT ++ ++ V + + +P RLG P E +V + E+ F Sbjct: 183 TKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPV-RRLGSPDEIGSIVAWLASEESGF 241 Query: 246 LNGEVIRLDGAIRM 259 G L+G + M Sbjct: 242 STGADFSLNGGLHM 255 >2UVD-A nrPDB Length = 246 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 81/261 (31%), Positives = 134/261 (51%), Gaps = 25/261 (9%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA-------KKLGNNCVF 60 +KG VA++TG + G+G A A L QGA+ V+ +G E +A KKLG++ + Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVV---NYAGNEQKANEVVDEIKKLGSDAIA 58 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 ADV + +DV + FG+VD+ VN AG+ + +K+ E++ V++ Sbjct: 59 VRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKE------EEWDTVINT 112 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL G F + V+ M + + G I+N ASV G GQA Y A+K G++G+T Sbjct: 113 NLKGVFLCTKAVSRFMMRQ------RHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTK 166 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ-- 238 A++LA I V IAPG T + L E + + +P ++ G+ + A+ V Sbjct: 167 TSAKELASRNITVNAIAPGFIATDMTDVLDENIKAEMLKLIP-AAQFGEAQDIANAVTFF 225 Query: 239 AIIENPFLNGEVIRLDGAIRM 259 A ++ ++ G+ + +DG + M Sbjct: 226 ASDQSKYITGQTLNVDGGMVM 246 >2CFC-A nrPDB Length = 250 Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 90/256 (35%), Positives = 128/256 (50%), Gaps = 24/256 (9%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK----LGNNCVFAPADVTS 67 VA++TG +SG GLA A R + +G LDL E A+ + + ADV Sbjct: 4 VAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVAD 63 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHT--LEDFQRVLDVNLMGT 125 E DV A+A +FG +DV VN AGI T N + G HT +E F +V+ VN+ G Sbjct: 64 EGDVNAAIAATMEQFGAIDVLVNNAGI-----TGNSEAGVLHTTPVEQFDKVMAVNVRGI 118 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F R V M QG GVI+N ASVA+ G++AY+ SKG ++ +T +A D Sbjct: 119 FLGCRAVLPHMLL----QGA--GVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVD 172 Query: 186 LAPIGIRVMTIAPGLFGTPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII- 241 A GIR + PG+ TP+ PE LA ++P +G A+ A V + Sbjct: 173 YAGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLA-RIP-QKEIGTAAQVADAVMFLAG 230 Query: 242 -ENPFLNGEVIRLDGA 256 + ++NG + +DGA Sbjct: 231 EDATYVNGAALVMDGA 246 >4KMS-A nrPDB Length = 249 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 126/256 (49%), Gaps = 27/256 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK---LGNNCVFAPADVTSE 68 +A++TGG G+G ATA L +G + V N + ++ + C +V Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKC----WNVADF 67 Query: 69 KDVQTALALAKGKFGR-VDVAVNCAGIAVASKTYNLKKGQTHTL--EDFQRVLDVNLMGT 125 ++ + A+ + +F + V + VN AGI K H + +D+ V++VNL Sbjct: 68 EECRQAVKEIEEEFKKPVSILVNNAGIT--------KDKMLHRMSHQDWNDVINVNLNSC 119 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 FN+ V +M + G I+N +S+ A GQVGQ YSA+K GI+G T +AR+ Sbjct: 120 FNMSSSVMEQM------RNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARE 173 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP- 244 A I V IAPG T ++ ++PE V + + +P RLG P E A V +++ Sbjct: 174 TASKNITVNCIAPGYIATEMVGAVPEDVLAKIINSIP-KKRLGQPEEIARAVAFLVDENA 232 Query: 245 -FLNGEVIRLDGAIRM 259 F+ GE I ++G M Sbjct: 233 GFITGETISINGGHNM 248 >2HSD-A nrPDB Length = 253 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 85/258 (32%), Positives = 133/258 (51%), Gaps = 19/258 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G +ITGGA GLG A + V GA VL D+ + G A A++LG+ + DVT Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTI 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 E+D Q +A A+ +FG VD VN AGI+ +T ++E F++V+++NL G F Sbjct: 63 EEDWQRVVAYAREEFGSVDGLVNNAGISTGMFL------ETESVERFRKVVEINLTGVFI 116 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 ++ V M D GG G I+N +S A G ++Y ASK G+ G++ A +L Sbjct: 117 GMKTVIPAM----KDAGG--GSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELG 170 Query: 188 PIGIRVMTIAPGLFGTPLL--TSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 IRV ++ PG+ TP+ T + + N+ P R+G+P E A V ++ + Sbjct: 171 TDRIRVNSVHPGMTYTPMTAETGIRQGEGNY--PNTPM-GRVGEPGEIAGAVVKLLSDTS 227 Query: 244 PFLNGEVIRLDGAIRMQP 261 ++ G + +DG P Sbjct: 228 SYVTGAELAVDGGWTTGP 245 >4RZH-A nrPDB Length = 247 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 86/265 (32%), Positives = 131/265 (49%), Gaps = 43/265 (16%) Query: 12 VAVITGGASGLGLATAERLVGQG-------------ASAVLLDLPNSGGEAQAKKLGNNC 58 VA++TG + G+G ATA L G A AV+ ++ +GGEA A + Sbjct: 8 VALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQ----- 62 Query: 59 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 A+V + +V + KF R+DV VN AGI + +K LED+Q V+ Sbjct: 63 ----ANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMK------LEDWQAVI 112 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 D+NL G F + V+ M + + G IIN SVA G GQA YSA+K G++G Sbjct: 113 DLNLTGVFLCTKAVSKLMLKQKS------GRIINITSVAGMMGNPGQANYSAAKAGVIGF 166 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSL-PEKVCNFLASQVPFPSRLGDPAEYAHLV 237 T +A++LA G+ V +APG T + +L E + F +P +R G P E A + Sbjct: 167 TKTVAKELASRGVTVNAVAPGFIATDMTENLNAEPILQF----IPL-ARYGQPEEVAGTI 221 Query: 238 QAIIENP---FLNGEVIRLDGAIRM 259 + + +P ++ G+ +DG + M Sbjct: 222 RFLATDPAAAYITGQTFNVDGGMVM 246 >1Q7C-A nrPDB Length = 244 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 75/253 (29%), Positives = 126/253 (49%), Gaps = 15/253 (5%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 +G +A++TG + G+G A AE L +GA + +G +A + LG N +VT Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDP 63 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 +++ L + +FG VD+ VN AGI + +K E++ +++ NL F + Sbjct: 64 ASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKD------EEWNDIIETNLSSVFRL 117 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + V M + + G II SV G GQA ++A+K G++G + +AR++A Sbjct: 118 SKAVMRAMMKK------RHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVAS 171 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ--AIIENPFL 246 GI V +APG T + +L + + +QVP RLG E A+ V A E ++ Sbjct: 172 RGITVNVVAPGFIETDMTRALSDDQRAGILAQVP-AGRLGGAQEIANAVAFLASDEAAYI 230 Query: 247 NGEVIRLDGAIRM 259 GE + ++G + M Sbjct: 231 TGETLHVNGGMYM 243 >3WOH-A nrPDB Length = 251 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 83/260 (31%), Positives = 128/260 (49%), Gaps = 23/260 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN--SGGEAQAK--KLGNNCVFAP 62 ++ G VA++TGG+ GLG A A RL GA+ ++ + + S E Q + +LG Sbjct: 8 ALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYR 67 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV+ + V + G VD+ VN AGI ++K ED+ V++ NL Sbjct: 68 CDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKD------EDYDAVMNTNL 121 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G F I+ A G + G IIN +SV+ G GQA Y+++K G++G+T I Sbjct: 122 KGAFLFIK--ACYFGFIRK----RSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSI 175 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFP-SRLGDPAEYAHLVQAII 241 A++LA +R +APGL T + L + P P R G P E A LV + Sbjct: 176 AKELAERNVRCNAVAPGLIATDMTQDLVDDSKRL----DPVPMRRFGRPDEVAGLVAFLA 231 Query: 242 --ENPFLNGEVIRLDGAIRM 259 E+ ++ G+V+ +DG + M Sbjct: 232 GDESSYITGQVVCVDGGMAM 251 >2CDH-G nrPDB Length = 244 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 119/254 (46%), Gaps = 22/254 (8%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFAPADVT 66 V V+TG + G+G A A L G+ VL++ S A Q + G + DV+ Sbjct: 3 VVVVTGASRGIGKAIALSL-GKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVS 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E DV+ + A +G +DV VN AGI + +KK Q + V+D+NL G F Sbjct: 62 KEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQ------WDEVIDLNLTGVF 115 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + M + ++G IIN ASV G +GQA Y+A+K G++G + AR+ Sbjct: 116 LCTQAATKIMMKK------RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREG 169 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP-- 244 A I V + PG + + L E + + +P R G P A LV+ + +P Sbjct: 170 ASRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPL-GRTGQPENVAGLVEFLALSPAA 228 Query: 245 -FLNGEVIRLDGAI 257 ++ G+ +DG I Sbjct: 229 SYITGQAFTIDGGI 242 >1HXH-A nrPDB Length = 253 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 84/258 (32%), Positives = 126/258 (48%), Gaps = 21/258 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 ++G VA++TGGASG+GL + L+G+GA D+ + G+ A +LG +F DV+S Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSS 63 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 E D +A + + G ++V VN AGI + +T LEDF R+L +N F Sbjct: 64 EADWTLVMAAVQRRLGTLNVLVNNAGILLPGDM------ETGRLEDFSRLLKINTESVF- 116 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + + G + G G IIN ASV+++ A YSASK + +T A Sbjct: 117 ----IGCQQGIAAMKETG--GSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCR 170 Query: 188 PIG--IRVMTIAPGLFGTPLL-TSLPEKVCNFLASQVPFPSRLGD---PAEYAHLV--QA 239 G IRV +I P TP++ SLP+ V + P +R G P A LV A Sbjct: 171 KQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLA 230 Query: 240 IIENPFLNGEVIRLDGAI 257 E+ ++G + D +I Sbjct: 231 SDESSVMSGSELHADNSI 248 >5IZ4-A nrPDB Length = 271 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 121/254 (47%), Gaps = 23/254 (9%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG------EAQAKKLGNNCVFAPADV 65 V VITG ASG+G ATA R G S + + +S EA + G + ADV Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ--RVLDVNLM 123 + D + A+ + ++ R+D +NCAG T + ++DF+ RV VNL+ Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAG-----TTRVIPHNAFDQIDDFEFERVYRVNLI 130 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G + + R + E + ++N +S+A G AY+ASKG + +TL +A Sbjct: 131 GLYQMTRAAVPLL--RESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLA 188 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEK-----VCNFLASQVPFPSRLGDPAEYAHLVQ 238 R+LAP IRV +APG+ LL + + V + + P R+ PAE A L Sbjct: 189 RNLAP-HIRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPL-KRVSRPAEIAELAW 246 Query: 239 AIIEN-PFLNGEVI 251 + + P + G+VI Sbjct: 247 FLTAHAPAITGQVI 260 >4K6F-A nrPDB Length = 255 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 80/256 (31%), Positives = 120/256 (46%), Gaps = 20/256 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCVFAPADVTS 67 +AV+TGG GLG A + RL G V+ PN+ G + G P DV Sbjct: 13 IAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVAD 72 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 Q + G VD+ VN AGI L K ++ V+ NL FN Sbjct: 73 HDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDK------VNWDAVIRTNLDSVFN 126 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + + V M ++G R I+N +SV +G VGQ Y+A+K G+ G T +A ++A Sbjct: 127 MTKPVCDGM----VERGWGR--IVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIA 180 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNF-LASQVPFPSRLGDPAEYAHLVQAII--ENP 244 G+ V T++PG T ++T++P+ + + + Q+P RLG P E A LV + E Sbjct: 181 RKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIP-AGRLGKPEEVAALVAYLCSEEAG 239 Query: 245 FLNGEVIRLDGAIRMQ 260 F+ G I ++G M Sbjct: 240 FVTGSNIAINGGQHMH 255 >3OSU-A nrPDB Length = 246 Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 73/254 (28%), Positives = 130/254 (51%), Gaps = 21/254 (8%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA-----KKLGNNCVFAPADVTS 67 A++TG + G+G + A +L +G + V ++ S +A+A K G + A+V Sbjct: 7 ALVTGASRGIGRSIALQLAEEGYN-VAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVAD 65 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 +V+ + +FG +DV VN AGI + +K+ +++ V+D NL G FN Sbjct: 66 ADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKE------QEWDDVIDTNLKGVFN 119 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ +M + + G IIN +SV G GQA Y A+K G++G+T AR+LA Sbjct: 120 CIQKATPQMLRQ------RSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELA 173 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PF 245 GI V +APG + + +L +++ + +Q+P +R G + A+ V + + + Sbjct: 174 SRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPL-ARFGQDTDIANTVAFLASDKAKY 232 Query: 246 LNGEVIRLDGAIRM 259 + G+ I ++G + M Sbjct: 233 ITGQTIHVNGGMYM 246 >3FTP-A nrPDB Length = 270 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 122/258 (47%), Gaps = 28/258 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA------QAKKLGNNCVFAPADV 65 VA++TG + G+G A A L +GA + +G E QA G V D Sbjct: 30 VAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLNVNDA 89 Query: 66 TS-EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 T+ + V++ L +FG ++V VN AGI +K +++ V+D NL Sbjct: 90 TAVDALVESTLK----EFGALNVLVNNAGITQDQLAMRMKD------DEWDAVIDTNLKA 139 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + R V P + G I+N SV G GQ Y+A+K G+ GMT +AR Sbjct: 140 VFRLSRAVL------RPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAR 193 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 244 ++ GI V +APG T + LP++ L +Q+P RLG P + AH V A + +P Sbjct: 194 EIGSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPL-GRLGSPEDIAHAV-AFLASP 251 Query: 245 ---FLNGEVIRLDGAIRM 259 ++ G + ++G + M Sbjct: 252 QAGYITGTTLHVNGGMFM 269 >1GEE-A nrPDB Length = 261 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 82/267 (30%), Positives = 129/267 (48%), Gaps = 24/267 (8%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVL-----LDLPNSGGEAQAKKLGNNCV 59 + ++G V VITG ++GLG + A R + A V+ D NS E + KK+G + Sbjct: 2 YKDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLE-EIKKVGGEAI 60 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 DVT E DV + A +FG++DV +N AG+ ++ + +L D+ +V+D Sbjct: 61 AVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEM------SLSDWNKVID 114 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 115 TNLTGAFLGSREAIKYFVENDI-----KGTVINMSSVHEKIPWPLFVHYAASKGGMKLMT 169 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSL---PEKVCNFLASQVPFPSRLGDPAEYAHL 236 +A + AP GIRV I PG TP+ PE+ + + S +P +G+P E A + Sbjct: 170 ETLALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRAD-VESMIPM-GYIGEPEEIAAV 227 Query: 237 VQAII--ENPFLNGEVIRLDGAIRMQP 261 + E ++ G + DG + + P Sbjct: 228 AAWLASSEASYVTGITLFADGGMTLYP 254 >2C07-A nrPDB Length = 285 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 67/251 (26%), Positives = 119/251 (47%), Gaps = 18/251 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAPADVTSE 68 VA++TG G+G A+ L + + + ++ + K G DV+ + Sbjct: 46 VALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSKK 105 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 +++ + + VD+ VN AGI + +K ++++ VL NL F + Sbjct: 106 EEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKN------DEWEDVLRTNLNSLFYI 159 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + ++ M N + G IIN +S+ G VGQA YS+SK G++G T +A++LA Sbjct: 160 TQPISKRMINN------RYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELAS 213 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP--FL 246 I V IAPG + + + E++ + S +P R+G P E A+L + + ++ Sbjct: 214 RNITVNAIAPGFISSDMTDKISEQIKKNIISNIP-AGRMGTPEEVANLACFLSSDKSGYI 272 Query: 247 NGEVIRLDGAI 257 NG V +DG + Sbjct: 273 NGRVFVIDGGL 283 >4IS3-A nrPDB Length = 268 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 124/259 (47%), Gaps = 22/259 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNN---CVFA 61 V+ V +ITGG G+G A A+ + GA + + AQ K+L FA Sbjct: 23 VQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFA 82 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 P D+TS V A+ K+GR+DV +N AGI + + + E+F+ ++D+N Sbjct: 83 P-DLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSE------EEFKHIMDIN 135 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + G FN G + + ++GVIINTASV G + Y ASK ++G+T Sbjct: 136 VTGVFN------GAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHG 189 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 + R++ IRV+ +APG+ T + P ++ +P R+ +P E A++ + Sbjct: 190 LGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPM-KRMLEPEEIANVYLFLA 248 Query: 242 EN--PFLNGEVIRLDGAIR 258 + + + +DGA R Sbjct: 249 SDLASGITATTVSVDGAYR 267 >4RZI-B nrPDB Length = 240 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 119/248 (47%), Gaps = 23/248 (9%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 V V+TGG G+G A + L GA DL GG +A LG A+VT + + Sbjct: 10 VIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA--LG-----VVANVTDLESM 62 Query: 72 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 A A K G V V AGI +K K T D+ VL+VNL G I+ Sbjct: 63 TAAAAEITDKLGPVYGVVANAGI---TKDNFFPK---LTPADWDAVLNVNLKGVAYSIKP 116 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 M + + G I+ +S++ G VGQ YSA+K G++GM +AR+ A G+ Sbjct: 117 FIEGMYER------KAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGV 170 Query: 192 RVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE---NPFLNG 248 R +APG T + ++ E + + ++PF R G P E A V ++ + ++ G Sbjct: 171 RANAVAPGFIDTEMTLAIREDIREKITKEIPF-RRFGKPEEIAWAVAFLLSPVASSYVTG 229 Query: 249 EVIRLDGA 256 EV+R++GA Sbjct: 230 EVLRVNGA 237 >3AUT-A nrPDB Length = 269 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 69/204 (33%), Positives = 105/204 (51%), Gaps = 17/204 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFA 61 +K V VITGG++GLG A A R GQ + V+++ N+ EA + ++ G + Sbjct: 12 DLKDKVVVITGGSTGLGRAMAVRF-GQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIV 70 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 DVT E+DV + A +FG +DV +N AG+ ++ L +L+++ +V+D N Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHEL------SLDNWNKVIDTN 124 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 125 LTGAFLGSREAIKYFVENDI-----KGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTET 179 Query: 182 IARDLAPIGIRVMTIAPGLFGTPL 205 +A + AP GIRV I PG TP+ Sbjct: 180 LALEYAPKGIRVNNIGPGAMNTPI 203 >5JS6-A nrPDB Length = 274 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 66/208 (31%), Positives = 104/208 (50%), Gaps = 18/208 (8%) Query: 30 LVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAV 89 V GA V+ D SGG A ++L VF DVT E DV+T ++ +FGR+D V Sbjct: 31 FVNSGARVVICDKDESGGRALEQEL-PGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVV 89 Query: 90 NCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGV 149 N AG + + + + + F+++L++NL+GT+ + +L + +++ G Sbjct: 90 NNAGHHPPPQ-----RPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-------GN 137 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL 209 +IN +S+ GQ Y A+KG + MT +A D +P G+RV I+PG TPL L Sbjct: 138 VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEEL 197 Query: 210 ----PEKVCNFLASQVPFP-SRLGDPAE 232 P+ + P R+G PAE Sbjct: 198 AALMPDPRATIREGMLAQPLGRMGQPAE 225 >3F9I-A nrPDB Length = 249 Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 126/256 (49%), Gaps = 27/256 (10%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----NCVFAPADV 65 G ++ITG +SG+G A A RL+ + S V++ N E + K LGN N ++ Sbjct: 14 GKTSLITGASSGIGSAIA-RLLHKLGSKVIISGSN---EEKLKSLGNALKDNYTIEVCNL 69 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 ++++ ++ K +D+ V AGI + +K +DF +V+D+NL Sbjct: 70 ANKEECSNLIS----KTSNLDILVCNAGITSDTLAIRMKD------QDFDKVIDINLKAN 119 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + R +M Q + G IIN +S+ G GQA Y ASK G++GMT ++ + Sbjct: 120 FILNREAIKKMIQK------RYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYE 173 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 +A GI V +APG + + L EK + ++P + G P + A+ V + N Sbjct: 174 VATRGITVNAVAPGFIKSDMTDKLNEKQREAIVQKIPLGT-YGIPEDVAYAVAFLASNNA 232 Query: 244 PFLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 233 SYITGQTLHVNGGMLM 248 >3EMK-A nrPDB Length = 246 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 75/255 (29%), Positives = 117/255 (45%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G A++TG GLG A A L QGA L + A +LG PA+++ Sbjct: 4 DLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLS 63 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + V+ A+ + G VD+ VN AGI + ED+ VL VNL F Sbjct: 64 DREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSD------EDWDAVLTVNLTSVF 117 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N+ R + P + G IIN S+ G GQA Y ASK G++G + +A+++ Sbjct: 118 NLTRELT------HPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEI 171 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENP 244 A + V IAPG + + L EK + + +P R+G A+ A V + E Sbjct: 172 ASRNVTVNCIAPGFIESAMTGKLNEKQKDAIMGNIPMK-RMGVGADIAAAVVYLASDEAA 230 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 231 YVTGQTLHVNGGMAM 245 >2Q2Q-A nrPDB Length = 255 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/205 (33%), Positives = 103/205 (50%), Gaps = 21/205 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE-----AQAKKLGNNCVFA 61 ++KG A++TG SG+GL A+ L GA+ VL N G+ A+ + G V Sbjct: 1 TLKGKTALVTGSTSGIGLGIAQVLARAGANIVL----NGFGDPAPALAEIARHGVKAVHH 56 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 PAD++ ++ ALA+ +FG VD+ VN AGI ++ + LE + +++ +N Sbjct: 57 PADLSDVAQIEALFALAEREFGGVDILVNNAGI------QHVAPVEQFPLESWDKIIALN 110 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L F+ RL M + G IIN ASV G G+AAY A+K G+VG+T Sbjct: 111 LSAVFHGTRLALPGM------RARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKV 164 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLL 206 + + A + I PG TPL+ Sbjct: 165 VGLETATSNVTCNAICPGWVLTPLV 189 >1UZM-A nrPDB Length = 247 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 119/248 (47%), Gaps = 23/248 (9%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 ++TGG G+GLA A+RL G + + + G A G DVT V Sbjct: 19 LVTGGNRGIGLAIAQRLAADGHK---VAVTHRGSGAPKGLFG-----VEVDVTDSDAVDR 70 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 A + G V+V V+ AG++ + + T E F++V++ NL G F V + + Sbjct: 71 AFTAVEEHQGPVEVLVSNAGLSADAFLMRM------TEEKFEKVINANLTGAFRVAQRAS 124 Query: 134 GEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRV 193 M +N + G +I SV+ G QA Y+ASK G++GM IAR+L+ + Sbjct: 125 RSMQRN------KFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTA 178 Query: 194 MTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ--AIIENPFLNGEVI 251 +APG T + +L E++ +P R+G PAE A +V A + +++G VI Sbjct: 179 NVVAPGYIDTDMTRALDERIQQGALQFIP-AKRVGTPAEVAGVVSFLASEDASYISGAVI 237 Query: 252 RLDGAIRM 259 +DG + M Sbjct: 238 PVDGGMGM 245 >4M8S-A nrPDB Length = 248 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/263 (28%), Positives = 126/263 (47%), Gaps = 24/263 (9%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCV 59 + + + G +A++TG + G+G A A+ L GA + SG A +++L G V Sbjct: 2 STQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRV 61 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 A+ + V+ +A + FG++D+ VN AGI + +K+ E++ ++ Sbjct: 62 LNSAE---PETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKE------EEWDDIMQ 112 Query: 120 VNLMGTFNVIRLV-AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 VNL F + V G M Q + G IIN SV G GQ Y+A+K G++G Sbjct: 113 VNLKSVFRASKAVLRGMMKQ-------RAGRIINITSVVGVMGNAGQTNYAAAKAGLIGF 165 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAH--L 236 + +AR++ GI V +APG T + +LPE+ +Q R GD + A L Sbjct: 166 SKSMAREVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTAL-GRFGDAQDIADAVL 224 Query: 237 VQAIIENPFLNGEVIRLDGAIRM 259 A + ++ G+ + ++G + M Sbjct: 225 FLASDQAKYITGQTLHVNGGMLM 247 >3WTC-A nrPDB Length = 262 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 62/218 (28%), Positives = 106/218 (48%), Gaps = 14/218 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK---LGNNCVFAPA 63 S+ G +A +TG A G+G A A RL GA +LLD+ AK+ LG V A Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTA 64 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 D+++ ++ LA A G +D+ VN AGI +++ + +++ +N+ Sbjct: 65 DISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAE------IEKIFSINVQ 118 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G ++ A + G +G IIN S+A EG AYSA+K + +T A Sbjct: 119 GVLWGMQAAATLFKEK-----GTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAA 173 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQV 221 ++LA GI V + PG+ GT + ++ +++ +++ Sbjct: 174 KELASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEI 211 >5VT6-A nrPDB Length = 269 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 78/256 (30%), Positives = 119/256 (46%), Gaps = 22/256 (8%) Query: 12 VAVITGGASGLGLATAERLVGQG-ASAVLLDLPN---SGGEAQAKKLGNNCVFAPADVTS 67 VA +TGG GLG A + RL G A AV N S + G + DV Sbjct: 27 VAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVAD 86 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + + FG+VDV +N AGI + + KG D+ V+ +L FN Sbjct: 87 FESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKG------DWDAVMRTDLDAMFN 140 Query: 128 VIR-LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 V + +AG + + + G I+N SV G GQA Y+++K GI G T +A + Sbjct: 141 VTKQFIAGMVER-------RFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALET 193 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNF-LASQVPFPSRLGDPAEYAHLVQAIIENP- 244 A GI V T++PG T ++ ++P+ V + Q+P RLG P E A L+ + + Sbjct: 194 AKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPV-GRLGRPDEVAALIAFLCSDDA 252 Query: 245 -FLNGEVIRLDGAIRM 259 F+ G + ++G + M Sbjct: 253 GFVTGADLAINGGMHM 268 >1GEG-A nrPDB Length = 256 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 76/261 (29%), Positives = 123/261 (47%), Gaps = 26/261 (9%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 VA++TG G+G A A RLV G + + D ++ +A A ++ G + V DV+ Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSDR 63 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 V A+ A+ G DV VN AG+A ++ ++ T E +V ++N+ G Sbjct: 64 DQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESI------TPEIVDKVYNINVKGVIWG 117 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 I+ A E + E G G IIN S A G A YS+SK + G+T ARDLAP Sbjct: 118 IQ-AAVEAFKKE----GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAP 172 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPS----------RLGDPAEYAHLVQ 238 +GI V PG+ TP+ + +V + + + RL +P + A V Sbjct: 173 LGITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVS 232 Query: 239 AII--ENPFLNGEVIRLDGAI 257 + ++ ++ G+ + +DG + Sbjct: 233 YLASPDSDYMTGQSLLIDGGM 253 >2GDZ-A nrPDB Length = 267 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 73/262 (27%), Positives = 120/262 (45%), Gaps = 35/262 (13%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG-----NNCVFAP 62 V G VA++TG A G+G A AE L+ +GA L+D G L +F Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV ++ ++ FGR+D+ VN AG+ + +++++ L +NL Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------------NNEKNWEKTLQINL 110 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP- 181 + + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 111 VSVISGTYLGLDYMSKQ---NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSA 167 Query: 182 -IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ-- 238 +A +L G+R+ I PG T +L S+ EK N + + + + D +Y ++ Sbjct: 168 ALAANLMNSGVRLNAICPGFVNTAILESI-EKEEN-MGQYIEYKDHIKDMIKYYGILDPP 225 Query: 239 -------AIIENPFLNGEVIRL 253 +IE+ LNG ++++ Sbjct: 226 LIANGLITLIEDDALNGAIMKI 247 >3V2H-A nrPDB Length = 281 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 66/206 (32%), Positives = 100/206 (48%), Gaps = 17/206 (8%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVL-----LDLPNSGGEAQAKKLGNNCVF 60 +S+ AVITG SG+GLA A L GA+ VL D + + A + Sbjct: 21 QSMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLH 80 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 PAD+T ++ +A+ +FG D+ VN AG+ K + +E + R++ V Sbjct: 81 HPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFP------VEQWDRIIAV 134 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL +F+ IR G P + G IIN AS ++AY A+K GI+G+T Sbjct: 135 NLSSSFHTIR------GAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTK 188 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLL 206 +A ++A G+ V +I PG TPL+ Sbjct: 189 TVALEVAESGVTVNSICPGYVLTPLV 214 >3RWB-A nrPDB Length = 247 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 118/254 (46%), Gaps = 18/254 (7%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEK 69 G A++TG A G+G A A RL GA+ ++ D+ G +A A +G AD++ Sbjct: 6 GKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPG 65 Query: 70 DVQTALALAKGKFGRVDVAVNCAGIA--VASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 V+ A + G +D+ VN A I VA + L+ +++++DVNL GTF Sbjct: 66 SVKALFAEIQALTGGIDILVNNASIVPFVAWDDVD--------LDHWRKIIDVNLTGTFI 117 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V R G ++ G+ G +I+ AS F G AAY A+KGG++G T +A +L Sbjct: 118 VTR-----AGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELG 172 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP--F 245 I + PGL + + + P + G P A +V + + + Sbjct: 173 KYNITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARW 232 Query: 246 LNGEVIRLD-GAIR 258 + G+ + +D G +R Sbjct: 233 ITGQTLNVDAGMVR 246 >5OJG-A nrPDB Length = 260 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 78/270 (28%), Positives = 127/270 (47%), Gaps = 25/270 (9%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 M + CR +G VA++T G+GLA AERL+ +GAS V+ + + L N + Sbjct: 1 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLT 60 Query: 61 APA----DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED--F 114 A + S D + + KFG++++ VN GI N G + D + Sbjct: 61 KVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGI-------NPAFGHILEVSDQVW 113 Query: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174 ++ +VN+ F + +LV + + +GG G II AS +A++ G AAY +K Sbjct: 114 DKLFEVNVKAGFQMTKLVHPHIAK----EGG--GAIIFNASYSAYKSPPGIAAYGVTKTT 167 Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL----PEKVCNFLASQVPFPSRLGDP 230 +VG+T +A LA IRV IAPG+ T + L + Q RLG P Sbjct: 168 LVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVP 227 Query: 231 AEYAHLVQAII--ENPFLNGEVIRLDGAIR 258 + A V + ++ ++ GE+I + G ++ Sbjct: 228 DDCAGTVAYLASDDSSYITGEMIIIAGGVQ 257 >2NM0-A nrPDB Length = 253 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 111/256 (43%), Gaps = 23/256 (8%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADV 65 RS ++TGG G+GLA A G + GE L C D+ Sbjct: 17 RSHMSRSVLVTGGNRGIGLAIARAFADAGDKVAI---TYRSGEPPEGFLAVKC-----DI 68 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T + V+ A + G V+V + AG+ + + EDF V++ NL GT Sbjct: 69 TDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSE------EDFTSVVETNLTGT 122 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F V++ N ++G ++ +SV G GQA Y+ASK G+VG +AR+ Sbjct: 123 FRVVKRA------NRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARE 176 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 L I +APG T + L ++ + SQVP R P E A V+ + + Sbjct: 177 LGSRNITFNVVAPGFVDTDMTKVLTDEQRANIVSQVPL-GRYARPEEIAATVRFLASDDA 235 Query: 244 PFLNGEVIRLDGAIRM 259 ++ G VI +DG + M Sbjct: 236 SYITGAVIPVDGGLGM 251 >2BGM-A nrPDB Length = 278 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 55/186 (29%), Positives = 96/186 (51%), Gaps = 13/186 (6%) Query: 27 AERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV--FAPADVTSEKDVQTALALAKGKFGR 84 A+ V GA V+ D+ + G+ +G+ V F DVT ++DV+ + K G+ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 85 VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQG 144 +D+ G+ + L+ G EDF+RV+D+N+ G F V + A M Sbjct: 93 LDIMFGNVGVLSTTPYSILEAGN----EDFKRVMDINVYGAFLVAKHAARVM------IP 142 Query: 145 GQRGVIINTASVAAFE-GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGT 203 ++G I+ TAS+++F G+ Y+A+K ++G+T + +L GIRV ++P + + Sbjct: 143 AKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVAS 202 Query: 204 PLLTSL 209 PLLT + Sbjct: 203 PLLTDV 208 >3OEC-A nrPDB Length = 317 Score = 84.0 bits (206), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 111/245 (45%), Gaps = 29/245 (11%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL----PN----SGGEAQAKKL 54 A ++G VA ITG A G G A RL GA V +DL PN G + K+ Sbjct: 39 ARMNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKET 98 Query: 55 -------GNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQ 107 G + ADV +Q + A +FG +D+ V+ GI+ + +L Sbjct: 99 VRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSL---- 154 Query: 108 THTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA 167 T + + +L NL+G ++ R V M + GQ G +I +S G GQ+ Sbjct: 155 --TDQQWSDILQTNLIGAWHACRAVLPSMIER-----GQGGSVIFVSSTVGLRGAPGQSH 207 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRL 227 Y+ASK G+ G+ L +A ++ IRV ++ PG T + +L EK+ + P+R Sbjct: 208 YAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVNTEM--ALNEKLLKMFLPHLENPTR- 264 Query: 228 GDPAE 232 D AE Sbjct: 265 EDAAE 269 >5ILO-A nrPDB Length = 271 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 67/213 (31%), Positives = 105/213 (49%), Gaps = 23/213 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGE---AQAKKLGNNCVFAP 62 S +G AV+TGGA G+GL +++L+ GA+ V ++DL ++ E +A + + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV ++K V+ FG +D+ VN AGI +N K D QR L VNL Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGI------FNDK--------DVQRTLLVNL 117 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G N MG+ D GG+ G+++N +SV + Y A+K GI+ T + Sbjct: 118 GGIINSTLSALPYMGK---DNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCL 174 Query: 183 ARD--LAPIGIRVMTIAPGLFGTPLLTSLPEKV 213 A + GI+ +T+ PG T + T+ EK+ Sbjct: 175 ANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKI 207 >4FC7-A nrPDB Length = 277 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 119/254 (46%), Gaps = 24/254 (9%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLD--LPN--SGGEAQAKKLGNNCVFAPADVTS 67 VA ITGG SG+G AE + G V+ LP + A G C+ DV + Sbjct: 29 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 88 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 V A+ A +FGR+D+ +NCA + + G + F+ V+D++ GTFN Sbjct: 89 PPAVMAAVDQALKEFGRIDILINCA-----AGNFLCPAGAL-SFNAFKTVMDIDTSGTFN 142 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V R++ + + D GG VI+N + GQ Q ++K + MT +A + Sbjct: 143 VSRVLYEKFFR---DHGG---VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 196 Query: 188 PIGIRVMTIAPG-LFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 244 P IRV ++APG + GT L L P+ + + P RLG+ E AH V + +P Sbjct: 197 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSV-LYLASP 254 Query: 245 ---FLNGEVIRLDG 255 ++ G V+ DG Sbjct: 255 LASYVTGAVLVADG 268 >4DBZ-A nrPDB Length = 281 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 77/244 (31%), Positives = 108/244 (44%), Gaps = 25/244 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA---PADVTSE 68 VA++TG SG+GL A RL +G + G K+L V A DV S Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRSV 87 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 +++ +A ++G VDV VN AG T L E + V++ NL G F V Sbjct: 88 PEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELAD------ELWLDVVETNLTGVFRV 141 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + V G E G I+N AS +G V A YSASK G+VG T + +LA Sbjct: 142 TKQVLKAGGMLERGTG----RIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELAR 197 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNF-----------LASQVPFPSRLGDPAEYAHLV 237 GI V + PG TP+ S+ E + + ++VP R P+E A +V Sbjct: 198 TGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPI-GRYVQPSEVAEMV 256 Query: 238 QAII 241 +I Sbjct: 257 AYLI 260 >3U5T-A nrPDB Length = 267 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 83/258 (32%), Positives = 122/258 (47%), Gaps = 32/258 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK--------LGNNCVFAPA 63 VA++TG + G+G A A RL G + V+ N G+A A + G + A A Sbjct: 29 VAIVTGASRGIGAAIAARLASDGFTVVI----NYAGKAAAAEEVAGKIEAAGGKALTAQA 84 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV+ V+ A A+ FG VDV VN AGI + F RV+ VNL Sbjct: 85 DVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAV------FDRVIAVNLK 138 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GTFN +R A + + G R + ++T+ V G Y+A+K G+ MT ++ Sbjct: 139 GTFNTLREAAQRL------RVGGRIINMSTSQVGLLHPSYG--IYAAAKAGVEAMTHVLS 190 Query: 184 RDLAPIGIRVMTIAPGLFGTPL-LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 ++L I V +APG T L L ++V + A P RLG P + A V A + Sbjct: 191 KELRGRDITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPL-ERLGTPQDIAGAV-AFLA 248 Query: 243 NP---FLNGEVIRLDGAI 257 P ++NG+V+R +G I Sbjct: 249 GPDGAWVNGQVLRANGGI 266 >4BO1-A nrPDB Length = 269 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 119/258 (46%), Gaps = 18/258 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA--- 63 S++G VA++TG + G+G A A L GA + SG E A+ L N V Sbjct: 24 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL 83 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV+S++ V L + G+ + VN AGI + +K +++ V++ NL Sbjct: 84 DVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKD------DEWFDVVNTNLN 137 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + + V M + + G IIN SV G GQ Y+A+K G+ G T +A Sbjct: 138 SLYRLSKAVLRGMTK------ARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALA 191 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 R++ I V +APG T + LPE L Q+P RLG E A +V + + Sbjct: 192 REVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPL-GRLGQAEEIAKVVGFLASD 250 Query: 244 --PFLNGEVIRLDGAIRM 259 ++ G + ++G + M Sbjct: 251 GAAYVTGATVPVNGGMYM 268 >3LYL-A nrPDB Length = 247 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 125/261 (47%), Gaps = 34/261 (13%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN----------CVFA 61 VA++TG + G+G A L +GA+ V + +A A+K N+ V Sbjct: 7 VALVTGASRGIGFEVAHALASKGATVV----GTATSQASAEKFENSMKEKGFKARGLVLN 62 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 +D+ S +Q A K + +D+ VN AGI + + + +++Q V++ N Sbjct: 63 ISDIES---IQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSE------DEWQSVINTN 113 Query: 122 LMGTFNVIR-LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 L F + + V G M + + G II+ SV G GQ Y A+K G++G + Sbjct: 114 LSSIFRMSKECVRGMMKK-------RWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSK 166 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ-- 238 +A ++A I V +APG T + L ++ +F+A+++P ++G+P + A V Sbjct: 167 SLAYEVASRNITVNVVAPGFIATDMTDKLTDEQKSFIATKIP-SGQIGEPKDIAAAVAFL 225 Query: 239 AIIENPFLNGEVIRLDGAIRM 259 A E ++ G+ + ++G + M Sbjct: 226 ASEEAKYITGQTLHVNGGMYM 246 >2PH3-A nrPDB Length = 245 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 76/260 (29%), Positives = 111/260 (42%), Gaps = 36/260 (13%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSG------------GEAQAKKLGNNCVF 60 A+ITG + G+G A A RL G + + N G LG N + Sbjct: 4 ALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANLL- 62 Query: 61 APADVTSEKDVQTALALAKGK-FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 E + TAL + G +D VN AGI + +K ED++ VL+ Sbjct: 63 -------EAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKD------EDWEAVLE 109 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL F R M + + G I+N SV G GQA Y ASK G++G T Sbjct: 110 ANLSAVFRTTREAVKLMMK------ARFGRIVNITSVVGILGNPGQANYVASKAGLIGFT 163 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 +A++ A GI V +APG T + LP++V Q+P R G P E A V Sbjct: 164 RAVAKEYAQRGITVNAVAPGFIETEMTERLPQEVKEAYLKQIP-AGRFGRPEEVAEAVAF 222 Query: 240 IIENP--FLNGEVIRLDGAI 257 ++ ++ G+ + +DG + Sbjct: 223 LVSEKAGYITGQTLCVDGGL 242 >5OVJ-A nrPDB Length = 256 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 78/248 (31%), Positives = 113/248 (45%), Gaps = 23/248 (9%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 ++TGG G+GLA A RL G + + + G A G C DVT V Sbjct: 28 LVTGGNRGIGLAIARRLAADGHK---VAVTHRGSGAPDDLFGVQC-----DVTDSAAVDR 79 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 A + G V+V V AGI SK L + T E F+ V++ NL G F + + Sbjct: 80 AFKEVEEHQGPVEVLVANAGI---SKDAFLMR---MTEERFEEVINTNLTGAFRCAQRAS 133 Query: 134 GEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRV 193 M Q + G II SV+ G QA Y+A+K G++GM I+R+LA G+ Sbjct: 134 RTM------QRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTA 187 Query: 194 MTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ--AIIENPFLNGEVI 251 +APG T + +L E++ +P R+G E A V A + ++ G VI Sbjct: 188 NVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAGAVI 246 Query: 252 RLDGAIRM 259 +DG + M Sbjct: 247 PVDGGMGM 254 >2EW8-A nrPDB Length = 249 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 77/261 (29%), Positives = 117/261 (44%), Gaps = 24/261 (9%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-PNSGGEAQAKKLGNNCVFAPA 63 + +K +AVITGGA+G+G A AER +GA + DL P EA + LG + Sbjct: 2 TQRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKC 61 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV+ DV+ FGR D+ VN AGI Y L T E +++ ++N+ Sbjct: 62 DVSQPGDVEAFGKQVISTFGRCDILVNNAGI------YPLIPFDELTFEQWKKTFEINVD 115 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F + + M +N G IIN S + Y ++K +G T +A Sbjct: 116 SGFLMAKAFVPGMKRN------GWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALA 169 Query: 184 RDLAPIGIRVMTIAPGLFGTPL-----LTSLPEKVCNFLASQVPFPSRLGDPAEY--AHL 236 DL GI V IAP L T L+++ + + N L + +P RL P + A Sbjct: 170 SDLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQA-IP---RLQVPLDLTGAAA 225 Query: 237 VQAIIENPFLNGEVIRLDGAI 257 A + F+ G+ + +DG + Sbjct: 226 FLASDDASFITGQTLAVDGGM 246 >5OVL-A nrPDB Length = 300 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 78/248 (31%), Positives = 113/248 (45%), Gaps = 23/248 (9%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 ++TGG G+GLA A RL G + + + G A G C DVT V Sbjct: 72 LVTGGNRGIGLAIARRLAADGHK---VAVTHRGSGAPDDLFGVQC-----DVTDSAAVDR 123 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 A + G V+V V AGI SK L + T E F+ V++ NL G F + + Sbjct: 124 AFKEVEEHQGPVEVLVANAGI---SKDAFLMR---MTEERFEEVINTNLTGAFRCAQRAS 177 Query: 134 GEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRV 193 M Q + G II SV+ G QA Y+A+K G++GM I+R+LA G+ Sbjct: 178 RTM------QRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTA 231 Query: 194 MTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ--AIIENPFLNGEVI 251 +APG T + +L E++ +P R+G E A V A + ++ G VI Sbjct: 232 NVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAGAVI 290 Query: 252 RLDGAIRM 259 +DG + M Sbjct: 291 PVDGGMGM 298 >3GRP-A nrPDB Length = 266 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/254 (25%), Positives = 113/254 (44%), Gaps = 13/254 (5%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G A++TG G+G A A QGA L + A LG + A+++ Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLS 83 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 K ++ +A+ + +D+ VN AGI ++ +D+ VL VNL Sbjct: 84 DRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQD------QDWDDVLAVNLTAAS 137 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + R + M + + G IIN S+ G GQ Y A+K G++G + +A+++ Sbjct: 138 TLTRELIHSMMRR------RYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEI 191 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSR-LGDPAEYAHLVQAIIENPF 245 A I V IAPG + + L EK + + +P +G+ +A + A E + Sbjct: 192 ASRNITVNCIAPGFIKSAMTDKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAY 251 Query: 246 LNGEVIRLDGAIRM 259 L G+ + ++G + M Sbjct: 252 LTGQTLHINGGMAM 265 >5YSS-A nrPDB Length = 256 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/211 (29%), Positives = 99/211 (46%), Gaps = 21/211 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-----LGNNCVFA 61 ++ G A++TG SG+GL A+ L GA+ +L N G+ A K G + Sbjct: 2 NLTGKTALVTGSTSGIGLGIAQVLAQAGATLIL----NGFGDVDAAKDAVAQYGKTPGYH 57 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 AD++ E + + A+ +FG VD+ +N AGI S +T ++ + ++ +N Sbjct: 58 GADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPI------ETFPVDKWNAIIAIN 111 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L F+ RL M + G IIN ASV ++AY A+K G+VG+T Sbjct: 112 LSSVFHTTRLALPGM------RARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKT 165 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEK 212 IA + A I + PG TPL+ +K Sbjct: 166 IALETAQTEITCNALCPGWVLTPLVQQQIDK 196 >1AE1-A nrPDB Length = 273 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 72/267 (26%), Positives = 125/267 (46%), Gaps = 37/267 (13%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQ-------AKKLGNNCV 59 S+KG A++TGG+ G+G A E L G GA S E + ++ G N Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTC----SRNEKELDECLEIWREKGLNVE 73 Query: 60 FAPADVTSEKDVQTALALAKGKF-GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 + D+ S + + F G++++ VN AG+ + K+ + T +D+ ++ Sbjct: 74 GSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIH------KEAKDFTEKDYNIIM 127 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 N +++ ++ + + Q G +I +S+A F + YSASKG I M Sbjct: 128 GTNFEAAYHLSQIAYPLL------KASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQM 181 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSL-------PEKVCNFLASQVPFPSRLGDPA 231 T +A + A IRV ++APG+ TPL+ + E++ NF+ + P R G P Sbjct: 182 TKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIV-KTPM-GRAGKPQ 239 Query: 232 EYAHLVQAIIENP---FLNGEVIRLDG 255 E + L+ A + P ++ G++I DG Sbjct: 240 EVSALI-AFLCFPAASYITGQIIWADG 265 >4TRR-A nrPDB Length = 269 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 62/210 (29%), Positives = 105/210 (50%), Gaps = 15/210 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA---KKLGNNCVFAPA 63 ++ G AV+TG ASG+G A L GA+ + DL G A A K G + Sbjct: 11 NLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAM 70 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DVT+E+ V T + FG VD+ V+ AGI + + N ++ D++++ +++ Sbjct: 71 DVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIEN------YSFADWKKMQAIHVD 124 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F + M ++ D+GG V+I SV + E ++AY +K G++G+ +A Sbjct: 125 GAFLTTKAALKHMYKD--DRGG---VVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLA 179 Query: 184 RDLAPIGIRVMTIAPGLFGTPLL-TSLPEK 212 ++ A +R + PG TPL+ +PE+ Sbjct: 180 KEGAKHNVRSHVVCPGFVRTPLVDKQIPEQ 209 >4IIN-A nrPDB Length = 271 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 68/253 (26%), Positives = 111/253 (43%), Gaps = 21/253 (8%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-----LGNNCVFAPADVTSE 68 +ITG + G+G A+ L G V ++ ++ A A K G D SE Sbjct: 33 LITGASKGIGAEIAKTLASMGLK-VWINYRSNAEVADALKNELEEKGYKAAVIKFDAASE 91 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 D A+ G + VN AG+ +K EDF V+D NL F Sbjct: 92 SDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKT------EDFHHVIDNNLTSAFIG 145 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 R M ++ + G ++N AS+ G +GQ YSASKGG++ M+ A + A Sbjct: 146 CREALKVMSKS------RFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGAL 199 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFL 246 IR ++ PG T + +L +++ +P +RLG E A V ++ + ++ Sbjct: 200 RNIRFNSVTPGFIETDMNANLKDELKADYVKNIPL-NRLGSAKEVAEAVAFLLSDHSSYI 258 Query: 247 NGEVIRLDGAIRM 259 GE ++++G + M Sbjct: 259 TGETLKVNGGLYM 271 >4AVY-A nrPDB Length = 242 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 117/248 (47%), Gaps = 31/248 (12%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-QAKKLGNNCVFAPADVTSEKDVQ 72 ++TGG+SG+G A A + GA V L L G A + ++ + D+T + +Q Sbjct: 15 LVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREEL----DITDSQRLQ 70 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV 132 R+DV VN AGI+ + Y+L F+RVL +NL ++ Sbjct: 71 RLFE----ALPRLDVLVNNAGISRDREEYDLAT--------FERVLRLNLSAA-----ML 113 Query: 133 AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 A ++ + Q G G I+N AS+ + G + AYSASKG IV +T +A + A IR Sbjct: 114 ASQLARPLLAQRG--GSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIR 171 Query: 193 VMTIAPGLFGTPLLTSLPEKV--CNFLASQVPFPSRLGDPAEYAHLVQAIIENP---FLN 247 V IAPG TPL L V + + P +R G+ E A A + P F+ Sbjct: 172 VNAIAPGWIDTPLGAGLKADVEATRRIMQRTPL-ARWGEAPEVAS-AAAFLCGPGASFVT 229 Query: 248 GEVIRLDG 255 G V+ +DG Sbjct: 230 GAVLAVDG 237 >1K2W-A nrPDB Length = 256 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 60/209 (28%), Positives = 96/209 (45%), Gaps = 11/209 (5%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G A+ITG A G+G A AE V +GA + D+ A A ++G DVT Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVTD 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + + +A ++G +D+ VN A + ++L T E + R+ +N+ GT Sbjct: 63 QASIDRCVAELLDRWGSIDILVNNAAL------FDLAPIVEITRESYDRLFAINVSGTLF 116 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 +++ VA M GG+ G IIN AS A G+ Y A+K ++ +T +L Sbjct: 117 MMQAVARAM-----IAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLI 171 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216 GI V IAPG+ + K ++ Sbjct: 172 RHGINVNAIAPGVVDGEHWDGVDAKFADY 200 >5U9P-A nrPDB Length = 265 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 75/260 (28%), Positives = 115/260 (44%), Gaps = 26/260 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL------GNNCVFA 61 + G A+ITG G+GL A L GA+ V+ D A++ ++ VF Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF- 76 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 DV V+ A+ + + G +D+ VN AGI + + H L + VN Sbjct: 77 --DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHAL------MRVN 128 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G FNV + VA M G IIN SV + + A Y+A+KG + +T Sbjct: 129 LDGVFNVAQAVARHMIAR------GHGKIINICSVQSELARPTIAPYAATKGAVRMLTKG 182 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEK--VCNFLASQVPFPSRLGDPAEY--AHLV 237 + D A GI+ +APG F T L +L + ++L + P R G E A + Sbjct: 183 MCADWARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTP-AGRWGQVDELCGAAIF 241 Query: 238 QAIIENPFLNGEVIRLDGAI 257 A + F+NG+ + +DG + Sbjct: 242 LASAASDFVNGQTLFVDGGL 261 >3V2G-A nrPDB Length = 271 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 119/259 (45%), Gaps = 29/259 (11%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA-----KKLGNNCVFA 61 S+ G A +TGG+ G+G A A+RL +GA AV L N+ AQA ++ G V Sbjct: 28 SLAGKTAFVTGGSRGIGAAIAKRLALEGA-AVALTYVNAAERAQAVVSEIEQAGGRAVAI 86 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 AD + ++ A+ G +D+ VN AGI ++ + T+ DF V+ VN Sbjct: 87 RADNRDAEAIEQAIRETVEALGGLDILVNSAGI------WHSAPLEETTVADFDEVMAVN 140 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 F IR + +G GG+ +I +++A G + YSASK + G+T Sbjct: 141 FRAPFVAIRSASRHLGD-----GGR--IITIGSNLAELVPWPGISLYSASKAALAGLTKG 193 Query: 182 IARDLAPIGIRVMTIAPGLFGT---PLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 +ARDL P GI V + PG T P E +A+ G+P + A LV Sbjct: 194 LARDLGPRGITVNIVHPGSTDTDMNPADGDHAEAQRERIAT-----GSYGEPQDIAGLVA 248 Query: 239 AII--ENPFLNGEVIRLDG 255 + + F+ G + +DG Sbjct: 249 WLAGPQGKFVTGASLTIDG 267 >3A28-C nrPDB Length = 258 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 84/264 (31%), Positives = 129/264 (48%), Gaps = 30/264 (11%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE-AQAKKL----GNNCVFAPADVT 66 VA++TGGA G+G +E+L G + DLP + A+ KL VF DVT Sbjct: 4 VAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDVT 63 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + + +A+ A K G DV VN AGIA +K T ED +++ VN+ F Sbjct: 64 DKANFDSAIDEAAEKLGGFDVLVNNAGIA------QIKPLLEVTEEDLKQIYSVNVFSVF 117 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 I+ + + D+ G +G IIN AS+AA +G +AYS +K + G+T A++L Sbjct: 118 FGIQAASRKF-----DELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQEL 172 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVC---------NF--LASQVPFPSRLGDPAEYAH 235 AP G V APG+ GT + + ++ NF +S + R P + A Sbjct: 173 APKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIAL-GRPSVPEDVAG 231 Query: 236 LVQAII-ENP-FLNGEVIRLDGAI 257 LV + EN ++ G+V+ +DG + Sbjct: 232 LVSFLASENSNYVTGQVMLVDGGM 255 >3WYE-A nrPDB Length = 256 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 82/262 (31%), Positives = 127/262 (48%), Gaps = 28/262 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 VA++TG G+G A A RLV G + + D ++ +A A ++ G + V DV+ Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSDR 63 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 V A+ A+ G DV VN AGIA +K T ED +++ VN+ F Sbjct: 64 DQVFAAVEQARKTLGGFDVIVNNAGIA------QIKPLLEVTEEDLKQIYSVNVFSVFFG 117 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 I+ A E + E G G IIN AS+AA +G +AYS +K + G+T ARDLAP Sbjct: 118 IQ-AAVEAFKKE----GHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAP 172 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVC---------NF--LASQVPFPSRLGDPAEYAHLV 237 +GI V PG+ GT + + ++ NF +S + R P + A LV Sbjct: 173 LGITVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIAL-GRPSVPEDVAGLV 231 Query: 238 QAII--ENPFLNGEVIRLDGAI 257 + ++ ++ G+ + +DG + Sbjct: 232 SFLASPDSDYMTGQSLLIDGGM 253 >1AHH-A nrPDB Length = 255 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 72/233 (30%), Positives = 112/233 (48%), Gaps = 20/233 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAPAD 64 + G A+ITG +G+G A GAS V+ D+ + ++LG D Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 +TSE+++ A K G+VD+ VN AG K +++ + DF+R ++N+ Sbjct: 69 ITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMP------MADFRRAYELNVFS 121 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F++ +LVA EM +N GG GVI+ S+AA + +Y++SK + +A Sbjct: 122 FFHLSQLVAPEMEKN----GG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAH 235 DL IRV IAPG T L S+ PE + + P RLG P + A+ Sbjct: 176 DLGEKNIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPI-RRLGQPQDIAN 226 >4MOW-A nrPDB Length = 256 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 115/258 (44%), Gaps = 26/258 (10%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA-----KKLGNNCVFAPAD 64 G VA++TG + G+G A A+ L +GA AV+++ +S A A + G V D Sbjct: 14 GKVAIVTGASKGIGAAIAKALADEGA-AVVVNYASSKAGADAVVSAITEAGGRAVAVGGD 72 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 V+ D Q + A +GR+DV VN +G+ Y + T E ++R D N+ G Sbjct: 73 VSKAADAQRIVDTAIETYGRLDVLVNNSGV------YEFAPIEAITEEHYRRQFDTNVFG 126 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + +G+ IIN +SV A YS +KG + +T +A Sbjct: 127 VLLTTQAAVKHLGEGAS--------IINISSVVTSITPPASAVYSGTKGAVDAITGVLAL 178 Query: 185 DLAPIGIRVMTIAPGLF---GTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 +L P IRV I PG+ GT + + + Q P RLG+P + A + + Sbjct: 179 ELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPL-GRLGEPNDIASVAVFLA 237 Query: 242 ENP--FLNGEVIRLDGAI 257 + ++ GE + + G + Sbjct: 238 SDDARWMTGEHLVVSGGL 255 >2AE2-A nrPDB Length = 260 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 65/263 (24%), Positives = 123/263 (46%), Gaps = 26/263 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN---SGGEAQAKKLGNNCVFAPA 63 +++G A++TGG+ G+G E L GAS + Q + G + Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVC 65 Query: 64 DVTSEKDVQTALALAKGKF-GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 D++S + Q + F G++++ VN AGI + K+ + +T+ED+ ++ +N Sbjct: 66 DLSSRSERQELMNTVANHFHGKLNILVNNAGIVI------YKEAKDYTVEDYSLIMSINF 119 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +++ L + + +RG ++ +SV+ +A Y A+KG + +T + Sbjct: 120 EAAYHLSVLAHPFL------KASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCL 173 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSL---PEKVCNF--LASQVPFPSRLGDPAEYAHLV 237 A + A IRV + PG+ T L+ PE+ N L + R+G+P E A +V Sbjct: 174 AFEWAKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCAL-RRMGEPKELAAMV 232 Query: 238 QAIIENP---FLNGEVIRLDGAI 257 A + P ++ G++I +DG + Sbjct: 233 -AFLCFPAASYVTGQIIYVDGGL 254 >3ZV3-A nrPDB Length = 281 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 63/203 (31%), Positives = 90/203 (44%), Gaps = 19/203 (9%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G VA+ITGGASGLG A +R V +GA +LD G N V DV S Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVRS 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED-----FQRVLDVNL 122 +D + A FG++D + AGI ++ ED F + VN+ Sbjct: 63 LQDQKRAAERCLAAFGKIDTLIPNAGI------WDYSTALADLPEDKIDAAFDDIFHVNV 116 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G + ++ P RG ++ T S A F G Y+A+K +VG+ + Sbjct: 117 KGYIHAVKACL-------PALVSSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQM 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPL 205 A +LAP +RV +APG T L Sbjct: 170 AFELAP-HVRVNGVAPGGMNTDL 191 >4Z9Y-A nrPDB Length = 253 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 71/254 (27%), Positives = 120/254 (47%), Gaps = 19/254 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDL--PNSGGEAQAKKLGNNCVFAPADV 65 ++G VA+ITG +GLG A L G V +++ P E + LG + AD+ Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIE-KVTALGRRFLSLTADM 66 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 ++ + A +FG VD+ VN AGI + +++ V+++N+ Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSE------KNWDDVMNLNIKSV 120 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + VA + + G+ G IIN AS+ +F+G + +Y+ASK ++G+T +A + Sbjct: 121 FFMSQTVARQFIKQ-----GKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANE 175 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYA--HLVQAII 241 A GI V IAPG T L E+ + ++P R G P + + A Sbjct: 176 WAKHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIP-AGRWGLPQDLMGPSVFLASS 234 Query: 242 ENPFLNGEVIRLDG 255 + ++NG I +DG Sbjct: 235 ASDYINGYTIAVDG 248 >3R3S-A nrPDB Length = 294 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 70/253 (27%), Positives = 113/253 (44%), Gaps = 25/253 (9%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-----LGNNCVFAP 62 +K A++TGG SG+G A A +GA + LP +AQ K G V P Sbjct: 47 LKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLLP 106 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 D++ E ++ + A+ G +D+ AG K + + + T E FQ+ VN+ Sbjct: 107 GDLSDESFARSLVHKAREALGGLDILALVAG-----KQTAIPEIKDLTSEQFQQTFAVNV 161 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F + + + + II T+S+ A++ Y+A+K I+ + + Sbjct: 162 FALFWITQEAIPLLPKG--------ASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGL 213 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTS---LPEKVCNFLASQVPFPSRLGDPAEYA--HLV 237 A+ +A GIRV +APG T L S +K+ F Q P R G PAE A ++ Sbjct: 214 AKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQF-GQQTPM-KRAGQPAELAPVYVY 271 Query: 238 QAIIENPFLNGEV 250 A E+ ++ EV Sbjct: 272 LASQESSYVTAEV 284 >4E6P-A nrPDB Length = 259 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 11/195 (5%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADV 65 + ++G A+ITG A G+G A AE V +GA+ + D+ A ++G DV Sbjct: 4 KRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDV 63 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T + + A+A G +D+ VN A + ++L T E ++++ +N+ GT Sbjct: 64 TRQDSIDAAIAATVEHAGGLDILVNNAAL------FDLAPIVEITRESYEKLFAINVAGT 117 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 ++ A +M G+ G IIN AS A G+ A Y A+K ++ +T D Sbjct: 118 LFTLQAAARQMIAQ-----GRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLD 172 Query: 186 LAPIGIRVMTIAPGL 200 L I V IAPG+ Sbjct: 173 LIKHRINVNAIAPGV 187 >3T7C-A nrPDB Length = 299 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 98/219 (44%), Gaps = 27/219 (12%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------------PNSGGEA--QAK 52 V+G VA ITG A G G + A L +GA + +D+ P+ E Q + Sbjct: 26 VEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVE 85 Query: 53 KLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE 112 LG + + DV +Q A+ + GR+D+ + A A+AS+ L + T Sbjct: 86 ALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVL--ANAALASEGTRLNRMDPKTWR 143 Query: 113 DFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRG-VIINTASVAAFEGQVGQAAYSAS 171 D +DVNL G + R+ + G+RG I+ T+S+ G Y AS Sbjct: 144 DM---IDVNLNGAWITARVAIPHI------MAGKRGGSIVFTSSIGGLRGAENIGNYIAS 194 Query: 172 KGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLP 210 K G+ G+ +A +L P IRV + P TP+L + P Sbjct: 195 KHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEP 233 >1X1T-A nrPDB Length = 260 Score = 70.5 bits (171), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 73/223 (32%), Positives = 101/223 (45%), Gaps = 39/223 (17%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQ---------AKKLGNNC 58 +KG VAV+TG SG+GL A L QGA VL N G+A A + G Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVL----NGFGDAAEIEKVRAGLAAQHGVKV 57 Query: 59 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDF---- 114 ++ AD++ + V+ + A + GR+D+ VN AGI T +EDF Sbjct: 58 LYDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQ-----------HTALIEDFPTEK 106 Query: 115 -QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173 +L +NL F+ M + QG R IIN AS ++AY A+K Sbjct: 107 WDAILALNLSAVFHGTAAALPHMKK----QGFGR--IINIASAHGLVASANKSAYVAAKH 160 Query: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPL----LTSLPEK 212 G+VG T A + A GI I PG TPL +++L EK Sbjct: 161 GVVGFTKVTALETAGQGITANAICPGWVRTPLVEKQISALAEK 203 >5B1Y-A nrPDB Length = 270 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 64/210 (30%), Positives = 102/210 (48%), Gaps = 23/210 (10%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGNNCVFAPADVTS 67 A++TGG+ G+G AT R +G S V+ DL E +A++LG+ + Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAE-EARRLGSPEAYTVRVDVG 84 Query: 68 EKDVQTALALAKGKF-GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + D T ++ G+ ++V VN AG+ L + ++ +++ L VNL G + Sbjct: 85 DPDSVTEMSSRVGELIPHLNVLVNAAGV------LQLGGIEETSISEWEETLRVNLTGVY 138 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV-GQAAYSASKGGIVGMTLPIARD 185 V +L+ + + + I+N AS+A G V AYSASK G++G+T +A Sbjct: 139 LVTKLLLPLL------RKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQ 192 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSL---PEK 212 LA GIRV +AP T + S PEK Sbjct: 193 LAGYGIRVNAVAPSFVETDMTRSFLDTPEK 222 >5O3Z-A nrPDB Length = 263 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 70/229 (30%), Positives = 96/229 (41%), Gaps = 28/229 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA-----DVT 66 VAV+ GG LG E L G + DL S A + + A D T Sbjct: 8 VAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDAT 67 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E V+ FGR D+ V AG+A A+ + L DF L VNL+G F Sbjct: 68 DEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFR------LTDFDLSLQVNLVGYF 121 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R + M ++ G +G II S + G + YSA+K G VG+T +A DL Sbjct: 122 LCSREFSKLMIRD-----GIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDL 176 Query: 187 APIGIRVMTIAPG-LFGTPLLTSL-----------PEKVCNFLASQVPF 223 A GI V ++ G L +P+ SL PE+V + +VP Sbjct: 177 AEYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPL 225 >2B4Q-A nrPDB Length = 276 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 68/260 (26%), Positives = 120/260 (46%), Gaps = 16/260 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG--NNCVFAPAD 64 S+ G +A++TGG+ G+G A+ L+ GA + A +L +C PAD Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 85 Query: 65 VTSEKDVQTALALAKGKF-GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 ++SE + LA A G+ R+D+ VN AG + + +++ + +++V+ +N+ Sbjct: 86 LSSEAGARR-LAQALGELSARLDILVNNAGTSWGAAL------ESYPVSGWEKVMQLNVT 138 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-AYSASKGGIVGMTLPI 182 F+ I+ + + ++ + R +IN SVA QA AY SK + ++ + Sbjct: 139 SVFSCIQQLLPLLRRSASAENPAR--VINIGSVAGISAMGEQAYAYGPSKAALHQLSRML 196 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFP-SRLGDPAEYAHLVQAI- 240 A++L I V IAPG F + + + A P R G P E A L ++ Sbjct: 197 AKELVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLA 256 Query: 241 -IENPFLNGEVIRLDGAIRM 259 ++ G VI +DG + Sbjct: 257 GTAGAYMTGNVIPIDGGFHL 276 >6CI9-A nrPDB Length = 259 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 66/256 (25%), Positives = 113/256 (44%), Gaps = 21/256 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGNNCVFA 61 S++G A++TGG+ G+G AE G V+ DL + + + Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTR--GKVTAV 63 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 ADVT +D + +A + G +D+ AGI + + +L T +D ++VL VN Sbjct: 64 RADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDL------TPDDIEQVLGVN 117 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 GT +++ + + G V++ ++ G G + Y ASK +G Sbjct: 118 FKGTVYIVQAALQALTAS-----GHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRT 172 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEY--AHLVQA 239 A +LAP I + + PG T L + + + +AS +P RLG A+ A L A Sbjct: 173 AAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIP-AGRLGSVADIGNAALFFA 231 Query: 240 IIENPFLNGEVIRLDG 255 E ++ G+ + +DG Sbjct: 232 TDEAAYVTGQTLVVDG 247 >5EJ2-A nrPDB Length = 308 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 60/216 (27%), Positives = 99/216 (45%), Gaps = 29/216 (13%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDL---------PNSGGEAQA------K 52 V G VA I+G A G G + A RL +GA + +D+ P+S E A K Sbjct: 35 VAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVK 94 Query: 53 KLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE 112 L V A DV + +++A+ + GR+D+ V AG+ + + H + Sbjct: 95 DLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGR-------KLHKIR 147 Query: 113 D--FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSA 170 D +Q ++D+NL G ++ ++ G GG+ G I+ T+SV + Y A Sbjct: 148 DNVWQDMIDINLTGVWHTVK-----AGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIA 202 Query: 171 SKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLL 206 +K G++G+ A +L P IRV + P T ++ Sbjct: 203 AKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMV 238 >1BDB-A nrPDB Length = 277 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 60/193 (31%), Positives = 89/193 (46%), Gaps = 11/193 (5%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 +KG +ITGGASGLG A +R V +GA +LD G+N + DV S Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRS 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE-DFQRVLDVNLMGTF 126 +D + A + +FG++D + AGI S L +L+ F V +N+ G Sbjct: 63 LEDQKQAASRCVARFGKIDTLIPNAGIWDYSTA--LVDLPEESLDAAFDEVFHINVKGYI 120 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + ++ P RG +I T S A F G Y+A+K IVG+ +A +L Sbjct: 121 HAVKACL-------PALVASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFEL 173 Query: 187 APIGIRVMTIAPG 199 AP +RV + G Sbjct: 174 APY-VRVNGVGSG 185 >4CR6-A nrPDB Length = 271 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 82/258 (31%), Positives = 121/258 (46%), Gaps = 20/258 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G A++TG A G+G AT E + +GAS V +DL + ++ G + D+ Sbjct: 13 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG--AIPIACDLAD 70 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + A+A A + G +D+ V AG A+ T N + D+ R +DVN+ GTF Sbjct: 71 RAAIDAAMADAVARLGGLDILV--AGGALKGGTGNFLD---LSDADWDRYVDVNMTGTFL 125 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 R A M + G+ II SV +F + AAY A+KGG+ +T +A DLA Sbjct: 126 TCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLA 185 Query: 188 PIGIRVMTIAPG---LFGTPLLTSLP---EKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 GI V IAPG + G S P E+V + +A P G P E A + Sbjct: 186 RHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRP-----GLPEEVATAAVFLA 240 Query: 242 EN--PFLNGEVIRLDGAI 257 E+ F+ G I +DG + Sbjct: 241 EDGSSFITGSTITIDGGL 258 >3UVE-A nrPDB Length = 286 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 61/218 (27%), Positives = 94/218 (43%), Gaps = 29/218 (13%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-----------------PNSGGEAQ 50 V+G VA +TG A G G + A RL +GA + +D+ P E Sbjct: 9 VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA 68 Query: 51 AKKLGNN--CVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQT 108 G+N V A DV ++ A+ + GR+D+ V AGI T + Sbjct: 69 DLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKT---- 124 Query: 109 HTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAY 168 + ED+ ++D+NL G + ++ M GG+ G II T+SV + Y Sbjct: 125 -SEEDWTEMIDINLAGVWKTVKAGVPHM-----IAGGRGGSIILTSSVGGLKAYPHTGHY 178 Query: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLL 206 A+K G+VG+ +L IRV ++ P TP+L Sbjct: 179 VAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPML 216 >1H5Q-A nrPDB Length = 265 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 23/230 (10%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGG----EAQAKKLGNNCVFAPADVTSEK 69 ++TGG G+GLA + GA+ ++ + E K+ G DV++ Sbjct: 18 IVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDVSNTD 77 Query: 70 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVI 129 V + G + + AG++V +K T EDF V DVN+ G FN Sbjct: 78 IVTKTIQQIDADLGPISGLIANAGVSV------VKPATELTHEDFAFVYDVNVFGVFNTC 131 Query: 130 RLVAGEMGQNEPDQGGQRGVIINTASVAA-------FEGQVGQAAYSASKGGIVGMTLPI 182 R VA Q + Q+G I+ T+S+++ G + Q Y++SK + + Sbjct: 132 RAVAKLWLQKQ-----QKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGL 186 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAE 232 A + A GIRV ++PG T + +K+ + AS +P +R P E Sbjct: 187 AAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPL-NRFAQPEE 235 >4DA9-A nrPDB Length = 280 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 13/215 (6%) Query: 49 AQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIA--VASKTYNLKKG 106 A+ LG +F AD+ Q + +FGR+D VN AGIA V +LK Sbjct: 72 AELSGLGARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKP- 130 Query: 107 QTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA 166 E+F ++ VNL GT + V M + D R IIN SV+A + Sbjct: 131 -----ENFDTIVGVNLRGTVFFTQAVLKAMLAS--DARASRS-IINITSVSAVMTSPERL 182 Query: 167 AYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSR 226 Y SK G+ + +A LA GI V + PG+ + + ++ K + S + R Sbjct: 183 DYCMSKAGLAAFSQGLALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLVPMRR 242 Query: 227 LGDPAEYAHLVQAII--ENPFLNGEVIRLDGAIRM 259 G+P + ++V + + F G VI+ DG + + Sbjct: 243 WGEPEDIGNIVAGLAGGQFGFATGSVIQADGGLSI 277 >3UN1-A nrPDB Length = 260 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 52/175 (29%), Positives = 86/175 (49%), Gaps = 14/175 (8%) Query: 81 KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNE 140 +FGR+D VN AG+ +A + T ED+ L VN+ G F++ + A EM + Sbjct: 93 RFGRIDSLVNNAGVFLAKPFVEM------TQEDYDHNLGVNVAGFFHITQRAAAEMLK-- 144 Query: 141 PDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGL 200 QG V I T+ V + A S +KGG+ +T +A + + G+RV ++PG+ Sbjct: 145 --QGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNAVSPGV 202 Query: 201 FGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDG 255 TP+ P + + LA P R+G+ + V + F+ GE++ +DG Sbjct: 203 IKTPM---HPAETHSTLAGLHPV-GRMGEIRDVVDAVLYLEHAGFITGEILHVDG 253 >5JY1-A nrPDB Length = 274 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 62/236 (26%), Positives = 104/236 (44%), Gaps = 22/236 (9%) Query: 33 QGASAVLLDLPNSGG---EAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAV 89 +GA+ ++ ++ S G E + +++G +F DVTS+ ++ A+ A +FG +D+ V Sbjct: 37 EGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTDVTSKASIEAAVRSAVEQFGSLDILV 96 Query: 90 NCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGV 149 N A + + K T E ++ L +L T+ +R M + + G Sbjct: 97 NNAFVPTPNVLLEEK-----TDEMLEQTLTTSLWATWWAMRAAFVPMRER------RWGR 145 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL 209 I+N S+ G Y+ +K GIVG+T A + I V IAP G L Sbjct: 146 IVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNAIAPTAMGATFF-EL 204 Query: 210 PEKVCNFL---ASQVPFPSRLGDPAEY---AHLVQAIIENPFLNGEVIRLDGAIRM 259 K F A+ P R GDP + A + A + F+ GE + +DG + + Sbjct: 205 AAKNPEFAERSAAARPL-GRSGDPEQDIGPAAVFFASEMSRFVTGETLHVDGGLHL 259 >4HP8-A nrPDB Length = 247 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 62/201 (30%), Positives = 93/201 (46%), Gaps = 23/201 (11%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLL--DLPNSGGEAQAKKLGNNC--VFAP 62 S++G A++TG +GLG A A L GA V P+ + AK GN + Sbjct: 6 SLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDF 65 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 AD + KD T D+ VN AGI + + + D+ V+DVNL Sbjct: 66 ADPLAAKDSFTDAGF--------DILVNNAGIIRRADSVEFSE------LDWDEVMDVNL 111 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F + A E+ G+ G ++N AS+ +F+G + +Y+A+K G+ G+T + Sbjct: 112 KALFFTTQAFAKELLAK-----GRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLL 166 Query: 183 ARDLAPIGIRVMTIAPGLFGT 203 A + A GI V IAPG T Sbjct: 167 ANEWAAKGINVNAIAPGYIET 187 >3W8F-A nrPDB Length = 260 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 64/214 (29%), Positives = 92/214 (42%), Gaps = 19/214 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVL------LDLPNSGGEAQAKKLGNNCVFA 61 +KG AV+TG SG+GLA A L GA V+ D+ ++K G + Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESK-FGVKAYYL 60 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 AD++ + + +A A G +D+ VN AGI T +E+F V N Sbjct: 61 NADLSDAQATRDFIAKAAEALGGLDILVNNAGIQ-----------HTAPIEEFP-VDKWN 108 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + N+ + G Q G IIN AS V ++AY A+K G+VG+T Sbjct: 109 AIIALNLSAVFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKV 168 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCN 215 A + A GI I PG TPL+ E + Sbjct: 169 TALENAGKGITCNAICPGWVRTPLVEKQIEAISQ 202 >4RGB-A nrPDB Length = 294 Score = 64.3 bits (155), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 72/285 (25%), Positives = 124/285 (43%), Gaps = 44/285 (15%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------PNSGGEAQ--------A 51 S+ G V ITG A G G + A QGA+ V +D+ P G + Sbjct: 22 SLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLV 81 Query: 52 KKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTL 111 +K G +F ADV + +Q +FG +D + AG+ + + + Sbjct: 82 EKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPD------ERDAS 135 Query: 112 EDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAF----EGQVGQAA 167 E + LD+ L+G +N ++ M + GQ G +I T+S+ A +G+ G A Sbjct: 136 EALRLGLDIMLIGVWNTFQVAIPHMKER-----GQGGNLIATSSMIALLDLTDGRGGTDA 190 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE---------KVCNFLA 218 Y SK I G+ A LA IRV +AP TP++T P + N ++ Sbjct: 191 YLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMS 250 Query: 219 SQVP-FPSRLGDPAEYAHLVQAIIENP--FLNGEVIRLDGAIRMQ 260 + +P FP + +P + ++ + +I + G V+++D + ++ Sbjct: 251 TALPDFP--MIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVK 293 >1DOH-A nrPDB Length = 283 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 71/272 (26%), Positives = 120/272 (44%), Gaps = 33/272 (12%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA-----KKLGNNCVFA 61 S++G VA++TG G+G A L G+ V+++ NS A+ KK G++ Sbjct: 26 SLEGKVALVTGAGRGIGREMAMEL-GRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACV 84 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 A+V +D+ A FG++D+ + +G+ ++ T E+F RV +N Sbjct: 85 KANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDV------TPEEFDRVFTIN 138 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 G F V R + + G R +++ + + A + A YS SKG I Sbjct: 139 TRGQFFVAREAYKHL------EIGGRLILMGSITGQA-KAVPKHAVYSGSKGAIETFARC 191 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSL------------PEKVCNFLASQVPFPSRLGD 229 +A D+A I V +APG T + ++ E+V + A Q R+G Sbjct: 192 MAIDMADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGL 251 Query: 230 PAEYAHLVQAIIENP--FLNGEVIRLDGAIRM 259 P + A +V + N ++ G+VI +DG M Sbjct: 252 PIDIARVVCFLASNDGGWVTGKVIGIDGGACM 283 >6NRP-A nrPDB Length = 263 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 117/258 (45%), Gaps = 37/258 (14%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA-----KKLGNNCVFAPADVTSE 68 ++TG + G+G A A +L G V + + EA+ + LG N + DV Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFD-VTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVNER 86 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH-------TLEDFQRVLDVN 121 + VQ L DV + V L G TH T +D+ V+ + Sbjct: 87 QTVQQIL--------EQDVEQHGGFYGVV-----LNAGLTHDGAFPALTDQDWDEVISTS 133 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G +NV++ + M +GG+ I+ +SV+ G GQ YSA+K G++G T Sbjct: 134 LDGFYNVLKPLI--MPMIHLRKGGR---IVTLSSVSGIMGNRGQVNYSAAKAGLIGATKA 188 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 +A +LA I V +APGL T ++T ++V +P R+G E A +V+ + Sbjct: 189 LALELAKRKITVNCVAPGLIETEMVT---DEVKEHALKMIPL-QRMGQVDEVASVVKFLC 244 Query: 242 --ENPFLNGEVIRLDGAI 257 E ++ +VI ++G + Sbjct: 245 SDEASYVTRQVISVNGGL 262 >4IIV-A nrPDB Length = 267 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 74/261 (28%), Positives = 115/261 (44%), Gaps = 24/261 (9%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGAS-AVLLDLPNSGGEAQAKKL---GNNC 58 A RSV ++TG + G+G A A +L G + V +G + + G N Sbjct: 24 AMSRSV-----LVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNG 78 Query: 59 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 DV + + + L + G V+ AGIA + L +D+ V+ Sbjct: 79 RLLSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSN------DDWDAVI 132 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 NL +NVI+ M QGG+ II +SV+ G GQ YSA+K GI+G Sbjct: 133 HTNLDSFYNVIQPCI--MPMIGARQGGR---IITLSSVSGVMGNRGQVNYSAAKAGIIGA 187 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 T +A +LA I V IAPGL T ++ + E S +P R+G E A L Sbjct: 188 TKALAIELAKRKITVNCIAPGLIDTGMI-EMEESALKEAMSMIPMK-RMGQAEEVAGLAS 245 Query: 239 AIIEN--PFLNGEVIRLDGAI 257 ++ + ++ +VI ++G + Sbjct: 246 YLMSDIAGYVTRQVISINGGM 266 >3UF0-A nrPDB Length = 273 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 75/265 (28%), Positives = 116/265 (43%), Gaps = 40/265 (15%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLL-----------DLPNSGGEAQAKKLG 55 S+ G AV+TG SG+G A A GA + ++ + GG A+A Sbjct: 28 SLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEA---- 83 Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 V AD+ +V LA + RVDV VN AGI + + G+ ++ Sbjct: 84 --VVADLADLEGAANVAEELAATR----RVDVLVNNAGIIARAPAEEVSLGR------WR 131 Query: 116 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 VL VNL + + R G G R I+ AS+ +F+G AAY+ASK + Sbjct: 132 EVLTVNLDAAWVLSR----SFGTAMLAHGSGR--IVTIASMLSFQGGRNVAAYAASKHAV 185 Query: 176 VGMTLPIARDLAPIGIRVMTIAPGLF---GTPLLTSLPEKVCNFLASQVPFPSRLGDPAE 232 VG+T +A + A G+ V +APG T L + E+ A ++P R P + Sbjct: 186 VGLTRALASEWAGRGVGVNALAPGYVVTANTAALRADDERAAEITA-RIP-AGRWATPED 243 Query: 233 YA--HLVQAIIENPFLNGEVIRLDG 255 + A +++G+V+ +DG Sbjct: 244 MVGPAVFLASDAASYVHGQVLAVDG 268 >1CYD-A nrPDB Length = 244 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 63/207 (30%), Positives = 94/207 (45%), Gaps = 26/207 (12%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK---LGNNCVFAPADVT 66 GL A++TG G+G T + L GA V + NS + AK+ + CV D+ Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCV----DLG 62 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + AL G G VD+ VN A + + + K E F R VNL F Sbjct: 63 DWDATEKAL----GGIGPVDLLVNNAALVIMQPFLEVTK------EAFDRSFSVNLRSVF 112 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 V ++VA +M G G I+N +S+ A YS++KG + +T +A +L Sbjct: 113 QVSQMVARDMINR-----GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMEL 167 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKV 213 P IRV ++ P T +LT + +KV Sbjct: 168 GPHKIRVNSVNP----TVVLTDMGKKV 190 >3O4R-A nrPDB Length = 261 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 71/257 (27%), Positives = 114/257 (44%), Gaps = 31/257 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL--------GNNCVFAPA 63 VA++T G+G A A RL GA V+ + L G C A Sbjct: 17 VALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKA 76 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH--TLEDFQRVLDVN 121 + E+ V TA+ L G +D+ V+ A + N G T E + + LD+N Sbjct: 77 E-DRERLVATAVKL----HGGIDILVSNAAV-------NPFFGSIMDVTEEVWDKTLDIN 124 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + + + V EM + +GG G ++ +S+AAF G + Y+ SK ++G+T Sbjct: 125 VKAPALMTKAVVPEMEK----RGG--GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKT 178 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLP-EKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 +A +LAP IRV +APGL T L +K + RLG+P + A +V + Sbjct: 179 LAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFL 238 Query: 241 I--ENPFLNGEVIRLDG 255 + ++ GE + + G Sbjct: 239 CSEDASYITGETVVVGG 255 >2ZAT-A nrPDB Length = 260 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 113/250 (45%), Gaps = 17/250 (6%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 VA++T G+GLA A RL GA V+ + L G + V Sbjct: 16 VALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKA 75 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 +D + +A+A G VD+ V+ A AV N+ T E + ++L VN+ T + Sbjct: 76 EDRERLVAMAVNLHGGVDILVSNA--AVNPFFGNIIDA---TEEVWDKILHVNVKATVLM 130 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + V EM + +GG G ++ +SV A+ Y+ SK ++G+T +A +LAP Sbjct: 131 TKAVVPEMEK----RGG--GSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAP 184 Query: 189 IGIRVMTIAPGLFGTPLLTSLP-EKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENPF 245 IRV +APGL T L +K + RLG+P + A +V + + + Sbjct: 185 RNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASY 244 Query: 246 LNGEVIRLDG 255 + GE + + G Sbjct: 245 ITGETVVVGG 254 >2FWM-X nrPDB Length = 250 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 61/195 (31%), Positives = 87/195 (44%), Gaps = 19/195 (9%) Query: 15 ITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTA 74 +TG G+G ATA V GA D + Q + V AD V Sbjct: 12 VTGAGKGIGYATALAFVEAGAKVTGFDQAFT----QEQYPFATEVMDVADAAQVAQVCQR 67 Query: 75 LALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAG 134 L LA+ + R+D VN AGI T L K ED+Q+ VN+ G FN+ + Sbjct: 68 L-LAETE--RLDALVNAAGILRMGATDQLSK------EDWQQTFAVNVGGAFNLFQQT-- 116 Query: 135 EMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVM 194 M Q +GG I+ AS AA ++G +AY ASK + + L + +LA G+R Sbjct: 117 -MNQFRRQRGG---AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 172 Query: 195 TIAPGLFGTPLLTSL 209 ++PG T + +L Sbjct: 173 VVSPGSTDTDMQRTL 187 >3OML-A nrPDB Length = 613 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/227 (29%), Positives = 99/227 (43%), Gaps = 27/227 (11%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDL--PNSGGEA----------QAKKLGNN 57 G VAV+TG +GLG A +GA V+ DL +SG A + +K G Sbjct: 19 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGE 78 Query: 58 CVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRV 117 V AD S D + A FGRVD+ VN AGI + +L K +D+ V Sbjct: 79 AV---ADYNSVIDGAKVIETAIKAFGRVDILVNNAGIL---RDRSLVKTSE---QDWNLV 129 Query: 118 LDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVG 177 DV+L G+F + M + G II T+S + G GQ Y+A+K G++G Sbjct: 130 NDVHLKGSFKCTQAAFPYMKKQ------NYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIG 183 Query: 178 MTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFP 224 + +A + A + I P LP+ + N L ++ P Sbjct: 184 LANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAP 230 >2QHX-A nrPDB Length = 328 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 71/277 (25%), Positives = 112/277 (40%), Gaps = 36/277 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD- 70 VA++TG A LG + AE L +G AV L S EA A N + +T + D Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEG-YAVCLHYHRSAAEANALSATLNARRPNSAITVQADL 106 Query: 71 --VQTA--------------------LALAKGKFGRVDVAVNCAGIAVASKTY-NLKKGQ 107 V TA +A +GR DV VN A + N + G Sbjct: 107 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 166 Query: 108 THTLEDFQ-------RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE 160 + D + + N + + +I+ A + G IIN + Sbjct: 167 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 226 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQ 220 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+ Sbjct: 227 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSK 284 Query: 221 VPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255 VP R AE + +V + + ++ G +++DG Sbjct: 285 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDG 321 >2BFA-A nrPDB Length = 288 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 71/280 (25%), Positives = 115/280 (41%), Gaps = 42/280 (15%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA------KKLGNNCVFAPADV 65 VA++TG A LG + AE L +G AV L S EA A + N+ + AD+ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEG-YAVCLHYHRSAAEANALSATLNARRPNSAITVQADL 66 Query: 66 TSEKDVQTA--------------------LALAKGKFGRVDVAVNCAGIAVASKTY-NLK 104 + +V TA +A +GR DV VN A + N + Sbjct: 67 S---NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDE 123 Query: 105 KGQTHTLEDFQ-------RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA 157 G + D + + N + + +I+ A + G IIN Sbjct: 124 DGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAM 183 Query: 158 AFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217 + +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V Sbjct: 184 TNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGH 241 Query: 218 ASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDG 255 S+VP R AE + +V + + ++ G +++DG Sbjct: 242 RSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDG 281 >1B15-A nrPDB Length = 254 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 107/250 (42%), Gaps = 44/250 (17%) Query: 21 GLGLATAERLVGQG-ASAVLLDL---PNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALA 76 G+GL T+ LV + + V+LD P + E +A N F DVT V + Sbjct: 16 GIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHTYDVTVP--VAESKK 73 Query: 77 LAKGKFGR---VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ--RVLDVNLMGTFNVIRL 131 L K F + VD+ +N AGI L+D Q R + +N G N Sbjct: 74 LLKKIFDQLKTVDILINGAGI----------------LDDHQIERTIAINFTGLVNTTTA 117 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-G 190 + + +GG G+I N SV F YSASK +V T +A+ LAPI G Sbjct: 118 ILDFWDKR---KGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK-LAPITG 173 Query: 191 IRVMTIAPGLFGTPLLTSLPE------KVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 244 + +I PG+ TPL+ + +V L S P++ + + V+AI N Sbjct: 174 VTAYSINPGITRTPLVHTFNSWLDVEPRVAELLLSH---PTQTSEQCG-QNFVKAIEANK 229 Query: 245 FLNGEVIRLD 254 NG + +LD Sbjct: 230 --NGAIWKLD 237 >4GKB-A nrPDB Length = 258 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 56/213 (26%), Positives = 87/213 (40%), Gaps = 29/213 (13%) Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 + P ++ + + A+A FGR+D VN AG+ + L G+ + F L+ Sbjct: 59 YLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGV---NDGIGLDAGR----DAFVASLE 111 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL+ + + P RG I+N +S A GQ + Y ASKG + +T Sbjct: 112 RNLIHYYAMAHYCV-------PHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALT 164 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSL------PEKVCNFLASQVPFPSRLGDPAEY 233 A L G+RV + P TPL + PE +A++VP R P E Sbjct: 165 REWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEI 224 Query: 234 AHLVQAII---------ENPFLNGEVIRLDGAI 257 A ++ E F++G LD A+ Sbjct: 225 ADTAVFLLSPRASHTTGEWLFVDGGYTHLDRAL 257 >4HBG-A nrPDB Length = 286 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 61/243 (25%), Positives = 100/243 (41%), Gaps = 51/243 (20%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN---------NCVFA- 61 VA++TG G+G A ++L +G S ++L E A G C A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 62 -----PADVTSE--------------KDVQTALALAKGKFGR------VDVAVNCAGIAV 96 P + E K + L K+ V++ +NCAG+ Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 97 ASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNE---PDQGGQ--RGVII 151 S + Q Q +++VN M + + M +++ P+ GQ R I+ Sbjct: 126 ESLSVRTTASQ------IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 Query: 152 NTASVAAFEGQV---GQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF-GTPLLT 207 N +S+ G++ G + YSASK + T +A ++ P IR TI+PGL GT ++ Sbjct: 180 NISSIL-HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 Query: 208 SLP 210 +LP Sbjct: 239 NLP 241 >3D3W-A nrPDB Length = 244 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 65/232 (28%), Positives = 99/232 (42%), Gaps = 26/232 (11%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 ++TG G+G T + L GA V + S +A L C D + Sbjct: 11 LVTGAGKGIGRGTVQALHATGARVVAV----SRTQADLDSLVRECPGIEPVCVDLGDWE- 65 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 A A G G VD+ VN A +A+ + K E F R +VNL V ++VA Sbjct: 66 ATERALGSVGPVDLLVNNAAVALLQPFLEVTK------EAFDRSFEVNLRAVIQVSQIVA 119 Query: 134 -GEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 G + + P G I+N +S + + Y ++KG + +T +A +L P IR Sbjct: 120 RGLIARGVP------GAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIR 173 Query: 193 VMTIAPGLFGTPL---LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 V + P + T + S P K L +++P LG AE H+V AI+ Sbjct: 174 VNAVNPTVVMTSMGQATWSDPHKAKTML-NRIP----LGKFAEVEHVVNAIL 220 >3PXX-A nrPDB Length = 287 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 65/231 (28%), Positives = 87/231 (37%), Gaps = 46/231 (19%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLD-----------------LPNSGGEAQ 50 V+ V ++TGGA G G + A +L +GA +L D L +G E + Sbjct: 8 VQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVE 67 Query: 51 AKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHT 110 K G A DV V LA A +FG++DV V AGI G Sbjct: 68 --KTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGIC--------PLGAHLP 117 Query: 111 LEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAF----------- 159 ++ F DV+ +G N + + II T SVA Sbjct: 118 VQAFADAFDVDFVGVINTVHAALPYLTSG--------ASIITTGSVAGLIAAAQPPGAGG 169 Query: 160 EGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLP 210 G A YS +K + TL +A LAP IR I P T +L S P Sbjct: 170 PQGPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAP 220 >3RKU-A nrPDB Length = 287 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 61/211 (28%), Positives = 91/211 (43%), Gaps = 20/211 (9%) Query: 3 AACRSVKGLVAVITGGASGLGLATA-ERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF- 60 AA R K V +ITG ++G+G ATA E L L+ + + K + F Sbjct: 27 AAERLAKKTV-LITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFP 85 Query: 61 ------APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDF 114 A D+T + ++ + +F +D+ VN AG A+ S + GQ T ED Sbjct: 86 NAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSD----RVGQIAT-EDI 140 Query: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174 Q V D N+ N+ + V Q G I+N S+A + + Y ASK Sbjct: 141 QDVFDTNVTALINITQAVLPIF------QAKNSGDIVNLGSIAGRDAYPTGSIYCASKFA 194 Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPL 205 + T + ++L IRV+ IAPGL T Sbjct: 195 VGAFTDSLRKELINTKIRVILIAPGLVETEF 225 >1MG5-A nrPDB Length = 255 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 60/205 (29%), Positives = 90/205 (43%), Gaps = 36/205 (17%) Query: 14 VITGGASGLGLATAERLVGQG-ASAVLLD-LPNSGGEAQAKKLGN--NCVFAPADVT--- 66 + G G+GL T++ L+ + + V+LD + N A+ K + F P DVT Sbjct: 10 IFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPI 69 Query: 67 --SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ--RVLDVNL 122 + K ++T A K VDV +N AGI L+D Q R + VN Sbjct: 70 AETTKLLKTIFAQLK----TVDVLINGAGI----------------LDDHQIERTIAVNY 109 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G N + + + +GG G+I N SV F YS +K +V T + Sbjct: 110 TGLVNTTTAI---LDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSL 166 Query: 183 ARDLAPI-GIRVMTIAPGLFGTPLL 206 A+ LAPI G+ T+ PG+ T L+ Sbjct: 167 AK-LAPITGVTAYTVNPGITRTTLV 190 >1YXM-A nrPDB Length = 303 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 62/262 (23%), Positives = 118/262 (45%), Gaps = 28/262 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN--------CV 59 ++G VA++TGGA+G+G A + L+ G++ V+ ++ A +L N + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 ++ +E++V + FG+++ VN G S ++ H VL+ Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA------VLE 129 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL GTF + + V + + GG II + A F V A++ G+ +T Sbjct: 130 TNLTGTFYMCKAVYSSWMK---EHGGSIVNII-VPTKAGFPLAVHSG---AARAGVYNLT 182 Query: 180 LPIARDLAPIGIRVMTIAPG-LFGTPLLTSLPEKVCNFLA---SQVPFPSRLGDPAEYAH 235 +A + A GIR+ +APG ++ + + +F ++P R+G P E + Sbjct: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEVSS 241 Query: 236 LVQAIIE--NPFLNGEVIRLDG 255 +V ++ F+ G+ + +DG Sbjct: 242 VVCFLLSPAASFITGQSVDVDG 263 >2X9N-A nrPDB Length = 288 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 66/267 (24%), Positives = 107/267 (40%), Gaps = 27/267 (10%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA------KKLGNNCVFAPADVT 66 AV+TG A +G A A +L Q V++ NS A + K+ N V AD+T Sbjct: 26 AVVTGAAKRIGRAIAVKL-HQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLT 84 Query: 67 SEK----DVQTALALAKGKFGRVDVAVNCAGIAVAS--------KTYNLKKGQTHTLEDF 114 + + + FGR DV VN A + N K +T E Sbjct: 85 NSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAE-- 142 Query: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174 ++ N + F + A P+ I+N + + + Y+ K Sbjct: 143 --LIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHA 200 Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYA 234 +VG+T A +LAP GIRV +APG+ P+ EK + +VP R + A Sbjct: 201 LVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEK--DKWRRKVPLGRREASAEQIA 258 Query: 235 HLVQAIIENP--FLNGEVIRLDGAIRM 259 V ++ ++ G +I++DG + + Sbjct: 259 DAVIFLVSGSAQYITGSIIKVDGGLSL 285 >2NWQ-A nrPDB Length = 272 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 12/188 (6%) Query: 15 ITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA--DVTSEKDVQ 72 ITG SG G A A R G S VL +A A +L P DV + Sbjct: 26 ITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRAAMS 85 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV 132 A+ +F + +N AG+A+ + Q+ L+D+ ++D N+ G RL+ Sbjct: 86 AAVDNLPEEFATLRGLINNAGLALGTD-----PAQSCDLDDWDTMVDTNIKGLLYSTRLL 140 Query: 133 AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 + + G I+N SVA G Y +K + +L + DL G+R Sbjct: 141 LPRLIAH-----GAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVR 195 Query: 193 VMTIAPGL 200 V + PGL Sbjct: 196 VTNLEPGL 203 >3GDF-A nrPDB Length = 267 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 62/231 (26%), Positives = 101/231 (43%), Gaps = 32/231 (13%) Query: 7 SVKGLVAVITG--GASGLGLATAERLVGQGAS-AVLLDLPNSGGEAQAKKL----GNNCV 59 S+KG V V+TG G G+G+ A GA+ A+ G E K+L G Sbjct: 17 SLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAK 76 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 V S + + + FG++D + AG S + ++E + V+ Sbjct: 77 AYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILD------GSVEAWNHVVQ 130 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTAS----VAAFEGQVGQAAYSASKGGI 175 V+L GTF+ + V G + ++G G ++ TAS +A F + Q +Y+ +K G Sbjct: 131 VDLNGTFHCAKAV----GHHFKERG--TGSLVITASMSGHIANFPQE--QTSYNVAKAGC 182 Query: 176 VGMTLPIA---RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPF 223 + M +A RD A RV +I+PG T L +P++ S +P Sbjct: 183 IHMARSLANEWRDFA----RVNSISPGYIDTGLSDFVPKETQQLWHSMIPM 229 >1P33-A nrPDB Length = 289 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 65/277 (23%), Positives = 110/277 (39%), Gaps = 36/277 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA------KKLGNNCVFAPADV 65 VA++TG A LG + AE L +G + V L S +A + N+ + AD+ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYT-VCLHYHRSAADASTLAATLNARRPNSAITVQADL 67 Query: 66 T-------SEKDVQTALAL----------AKGKFGRVDVAVNCAGIAVASKTYNLKKGQT 108 + SE D + L +GR DV VN A + G+ Sbjct: 68 SNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEG 127 Query: 109 HTLEDFQRVLDV--------NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE 160 + + L+V N + + +I+ A + +Q G I+N + Sbjct: 128 GSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQ 187 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQ 220 +G Y+ +K + G+T A +LA + IRV ++PGL P +P V + Sbjct: 188 PLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--DDMPFSVQEDYRRK 245 Query: 221 VPFPSRLGDPAEYAHLVQAII--ENPFLNGEVIRLDG 255 VP R E + +V + + ++ G I++DG Sbjct: 246 VPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDG 282 >2AG5-A nrPDB Length = 246 Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 52/202 (25%), Positives = 87/202 (43%), Gaps = 28/202 (13%) Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DVT +K + + R+DV N AG + ++ +D+ +++N+ Sbjct: 58 DVTKKKQIDQF----ANEVERLDVLFNVAGFVHHGTVLDCEE------KDWDFSMNLNVR 107 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPI 182 + +I+ +M + G IIN +SVA+ +G V + YS +K ++G+T + Sbjct: 108 SMYLMIKAFLPKM------LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSV 161 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSL------PEKVCN-FLASQVPFPSRLGDPAEYAH 235 A D GIR + PG TP L PE+ N FL Q R E A Sbjct: 162 AADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK--TGRFATAEEIAM 219 Query: 236 LVQAII--ENPFLNGEVIRLDG 255 L + E+ ++ G + +DG Sbjct: 220 LCVYLASDESAYVTGNPVIIDG 241 >3O26-A nrPDB Length = 311 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----NCVFAPAD 64 K AV+TGG G+G ++L G VL + G +KL N N VF D Sbjct: 11 KRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLD 70 Query: 65 VTSEKDVQTALA-LAKGKFGRVDVAVNCAGIA 95 VT ++LA K FG++D+ VN AG+A Sbjct: 71 VTDPIATMSSLADFIKTHFGKLDILVNNAGVA 102 >6CGE-A nrPDB Length = 328 Score = 47.4 bits (111), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 60/212 (28%), Positives = 93/212 (43%), Gaps = 29/212 (13%) Query: 12 VAVITGGASGLGLATAERLVGQGAS-----AVLLDLPNSGGEAQAKKLGNNCVFAPADV- 65 V +ITG +SG+GL A RL + A L DL G +A + P + Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAAR---ALACPPGSLE 61 Query: 66 TSEKDVQTALALAKGKF----GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 T + DV+ + ++A + GRVDV V AG+ + L + + VLDVN Sbjct: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVN 115 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 ++GT +++ +M + G ++ T SV G Y ASK + G+ Sbjct: 116 VVGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 169 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213 +A L P G+ + I G P+ T+ EKV Sbjct: 170 LAVLLLPFGVHLSLIECG----PVHTAFMEKV 197 >1A27-A nrPDB Length = 289 Score = 47.4 bits (111), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 61/212 (28%), Positives = 94/212 (44%), Gaps = 29/212 (13%) Query: 12 VAVITGGASGLGLATAERLVGQGAS-----AVLLDLPNSGGEAQAKKLGNNCVFAPADV- 65 V +ITG +SG+GL A RL + A L DL G +A + C P + Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAAR-ALAC--PPGSLE 60 Query: 66 TSEKDVQTALALAKGKF----GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 T + DV+ + ++A + GRVDV V AG+ + L + + VLDVN Sbjct: 61 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVN 114 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 ++GT +++ +M + G ++ T SV G Y ASK + G+ Sbjct: 115 VVGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 168 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213 +A L P G+ + I G P+ T+ EKV Sbjct: 169 LAVLLLPFGVHLSLIECG----PVHTAFMEKV 196 >1O5I-A nrPDB Length = 249 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 61/251 (24%), Positives = 106/251 (42%), Gaps = 28/251 (11%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 ++ + G+G A A+ L +GA + + E K+ G+ V D++ Sbjct: 23 LVLAASRGIGRAVADVLSQEGAEVTIC----ARNEELLKRSGHRYVVC--------DLRK 70 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 L L K VD+ V AG A L T EDF+ +D + ++R Sbjct: 71 DLDLLFEKVKEVDILVLNAGGPKAGFFDEL------TNEDFKEAIDSLFLNMIKIVRNYL 124 Query: 134 GEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRV 193 M + +G R V I + SV + + + ++++ + G ++ ++AP GI V Sbjct: 125 PAMKE----KGWGRIVAITSFSVISPIENLYTS--NSARMALTGFLKTLSFEVAPYGITV 178 Query: 194 MTIAPGLFGTPLLTS-LPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP--FLNGEV 250 +APG T + L E+ + SQ+P R+ P E A +V + +L G+ Sbjct: 179 NCVAPGWTETERVKELLSEEKKKQVESQIPM-RRMAKPEEIASVVAFLCSEKASYLTGQT 237 Query: 251 IRLDGAIRMQP 261 I +DG + P Sbjct: 238 IVVDGGLSKFP 248 >3V8B-A nrPDB Length = 283 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 58/196 (29%), Positives = 90/196 (45%), Gaps = 14/196 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 VA+ITG SG+G ATA L G + L + E A ++ G + ADV+ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGI-AVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 ++ A+ KFG +D+ V AGI V + +LK + + + VNL GTF Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFE------WDETIAVNLRGTFL 143 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + L + Q +GG V++++ + G AY+A+K V + +A +L Sbjct: 144 TLHLTVPYLKQ----RGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELG 199 Query: 188 PIGIRVMTIAPGLFGT 203 IRV + PG T Sbjct: 200 KHHIRVNAVCPGAIET 215 >4EGF-A nrPDB Length = 266 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 55/185 (29%), Positives = 80/185 (43%), Gaps = 22/185 (11%) Query: 82 FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141 FG +DV VN AGI+ + + F + VNL L+A +G+ Sbjct: 96 FGGLDVLVNNAGISHPQPVVDTDP------QLFDATIAVNLRAP----ALLASAVGKAMV 145 Query: 142 DQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF 201 G+ G II AS AA AY SK G+V T +AR+L P GIR ++ P Sbjct: 146 -AAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVCP--- 201 Query: 202 GTPLLTSLPEKVCNFLASQVPFPSRL-----GDPAEYAHLVQAIIEN--PFLNGEVIRLD 254 T +LT + ++V A P +R+ P E + V + + +NG I +D Sbjct: 202 -TVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVDIPVD 260 Query: 255 GAIRM 259 G M Sbjct: 261 GGYTM 265 >3U9L-A nrPDB Length = 324 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 59/199 (29%), Positives = 89/199 (44%), Gaps = 21/199 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGAS--AVLLDLPN---SGGEAQAKKLGNNCV---FAPA 63 + +ITG +SG G TAE L G G A + D+ S EA A +N V Sbjct: 7 IILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLEL 66 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV S+ V A+ G+ GR+DV ++ AG V + T E F + D+N++ Sbjct: 67 DVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMV------FGPAEAFTPEQFAELYDINVL 120 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQ-AAYSASKGGIVGMTLPI 182 T V R M + + G++I +S ++ G A Y A+K + + + Sbjct: 121 STQRVNRAALPHMRRQ------KHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQY 174 Query: 183 ARDLAPIGIRVMTIAPGLF 201 AR+L+ GI I PG F Sbjct: 175 ARELSRWGIETSIIVPGAF 193 >3OIC-A nrPDB Length = 258 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 18/205 (8%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFAPADVTS 67 A++TG + G+G A A RL G + ++++ S A + +KLG + A+V Sbjct: 7 ALVTGSSRGVGKAAAIRLAENGYN-IVINYARSKKAALETAEEIEKLGVKVLVVKANVGQ 65 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 ++ FGR+DV VN A V L+ +TH + +++N Sbjct: 66 PAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELE--ETH----WDWTMNINAKALLF 119 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + A M +N GG G I++ +S+ + SK + +T +A +L+ Sbjct: 120 CAQEAAKLMEKN----GG--GHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELS 173 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEK 212 P I V ++ G T L P + Sbjct: 174 PKQIIVNAVSGGAIDTDALKHFPNR 198 >5LCX-A nrPDB Length = 316 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGG-EAQAKKLG------NNCVFAPADV 65 A++TG G+G +L +G +L G EA+ K L N VF DV Sbjct: 10 ALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDV 69 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIA 95 T V K KFG++D+ VN AG++ Sbjct: 70 TDLASVAAVAVFIKSKFGKLDILVNNAGVS 99 >4DRY-A nrPDB Length = 281 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 13/163 (7%) Query: 27 AERLVGQGASAVLL----DLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKF 82 A+ L +G S V+ D+ ++ + GN DV V A + +F Sbjct: 50 AQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAEF 109 Query: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142 R+D+ VN AG V + T E + ++ NL G F + M P Sbjct: 110 ARLDLLVNNAGSNVPPVPL-----EEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTP- 163 Query: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 +GG+ IIN S++A + A Y+A+K I G+T A D Sbjct: 164 RGGR---IINNGSISAQTPRPNSAPYTATKHAITGLTKSTALD 203 >2DKN-A nrPDB Length = 255 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 68/263 (25%), Positives = 110/263 (41%), Gaps = 36/263 (13%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 V ITG ASG+G A E L G + + +D G+A + AD+++ Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDR----GQADIE----------ADLSTPGGR 48 Query: 72 QTALALAKGKFGRV-DVAVNCAGIAVASKTYNL-----KKGQTHTLEDFQRVLDVN---- 121 +TA+A + G V D V CAG+ V + L G + L+ L Sbjct: 49 ETAVAAVLDRCGGVLDGLVCCAGVGVTAANSGLVVAVNYFGVSALLDGLAEALSRGQQPA 108 Query: 122 --LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 ++G+ + A E+ E G I +A +GQ AY+ SK + + Sbjct: 109 AVIVGSIAATQPGAAELPMVEAMLAGDEARAIE---LAEQQGQT-HLAYAGSKYAVTCLA 164 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 D A G+R+ +APG TPLL + + + S F + LG +E + +A Sbjct: 165 RRNVVDWAGRGVRLNVVAPGAVETPLLQA-SKADPRYGESTRRFVAPLGRGSEPREVAEA 223 Query: 240 II-----ENPFLNGEVIRLDGAI 257 I + F++G V+ +DG + Sbjct: 224 IAFLLGPQASFIHGSVLFVDGGM 246 >1FJH-A nrPDB Length = 257 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 72/279 (25%), Positives = 115/279 (41%), Gaps = 56/279 (20%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 + VI+G A+G+G AT + L G V +D+ ++ AD+++ + Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE--------------VIADLSTAEGR 48 Query: 72 QTALA--LAKGKFGRVDVAVNCAGIAVASKTYN--------------------LKKGQTH 109 + A+A LAK G +D V CAG+ +K LKKG Sbjct: 49 KQAIADVLAKCSKG-MDGLVLCAGLGPQTKVLGNVVSVNYFGATELMDAFLPALKKGHQP 107 Query: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYS 169 V +L N + L A E G+ + R ++ + Q G AY+ Sbjct: 108 AAVVISSVASAHLAFDKNPLAL-ALEAGE----EAKARAIVEHAGE------QGGNLAYA 156 Query: 170 ASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTS--LPEKVCNFLASQVPFPSRL 227 SK + A G+R+ TIAPG TPLL + + +A VP R Sbjct: 157 GSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPMGRR 216 Query: 228 GDPAEYAHLVQAIIENP---FLNGEVIRLDGAIR--MQP 261 +P+E A ++ A + +P +++G I +DG I M+P Sbjct: 217 AEPSEMASVI-AFLMSPAASYVHGAQIVIDGGIDAVMRP 254 >3KZV-A nrPDB Length = 254 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 45/208 (21%), Positives = 90/208 (43%), Gaps = 20/208 (9%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFAPADV 65 G V ++TG + G+G + + L V+ + S EA KKL G+ + D+ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARS--EAPLKKLKEKYGDRFFYVVGDI 59 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T + ++ + A G++D V AG+ + N + ++++ D+N Sbjct: 60 TEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVN-----EIDVNAWKKLYDINF--- 111 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F+++ LV G P+ G ++ +S A AY +SK + + +A + Sbjct: 112 FSIVSLV----GIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE 167 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKV 213 ++ + +APG+ T + ++ E V Sbjct: 168 ERQ--VKAIAVAPGIVDTDMQVNIRENV 193 >3E9N-A nrPDB Length = 245 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 61/239 (25%), Positives = 100/239 (41%), Gaps = 28/239 (11%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 S+K +AV+TG G+G+ + L L P A A+ G P + Sbjct: 2 SLKKKIAVVTGATGGMGIEIVKDLSRDHIVYALGRNPEHLA-ALAEIEG----VEPIESD 56 Query: 67 SEKDVQTALALAKGK-FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 K+V + K K VD V+ A +A + ++ G ++ ++ LD+N+ Sbjct: 57 IVKEVLEEGGVDKLKNLDHVDTLVHAAAVA---RDTTIEAG---SVAEWHAHLDLNV--- 107 Query: 126 FNVIRLVAGEMG-QNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 +V E+ Q P G +I S A G Y+ASK + G+ + Sbjct: 108 -----IVPAELSRQLLPALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRK 162 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLPEKV-CNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 + A GIRV T++PG TP+L L + NF P +P E A+ ++ +I+ Sbjct: 163 EEANNGIRVSTVSPGPTNTPMLQGLMDSQGTNF------RPEIYIEPKEIANAIRFVID 215 >5L51-A nrPDB Length = 324 Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGG-EAQAK-------KLGNNCVFAPAD 64 AV+TG G+G ++L +G + +L G EA+ + + G+ V D Sbjct: 18 AVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQLD 77 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGI 94 V V + K KFG +D+ VN AG+ Sbjct: 78 VADPASVAALVDFIKTKFGSLDILVNNAGL 107 >1N5D-A nrPDB Length = 288 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 10/121 (8%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKL---GNNCVFAPADVTS 67 VA++TG G+G A L Q A V+L + + G+A K+L G + F D+ Sbjct: 6 VALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDIID 65 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + ++ + ++G +DV VN A IA + L ++ + + N MGT N Sbjct: 66 LQSIRALCDFLRKEYGGLDVLVNNAAIA-----FQLDNPTPFHIQA-ELTMKTNFMGTRN 119 Query: 128 V 128 V Sbjct: 120 V 120 >3UCF-A nrPDB Length = 223 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 5/84 (5%) Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFP-SRLGDPA 231 I T +A++LAPI RV I+PGL T + ++ + +Q P ++G+ + Sbjct: 137 IEATTKVLAKELAPI--RVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEAS 194 Query: 232 EYAHLVQAIIENPFLNGEVIRLDG 255 + A I+N ++ G VI +DG Sbjct: 195 DIAMAYLFAIQNSYMTGTVIDVDG 218 >3BHI-A nrPDB Length = 276 Score = 34.7 bits (78), Expect = 0.046, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKL---GNNCVFAPADVTS 67 VA++TGG G+GLA L + V+L + + G+A ++L G + F D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIA 95 + ++ + ++G +DV VN AGIA Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGIA 93 >2HRB-A nrPDB Length = 274 Score = 33.9 bits (76), Expect = 0.070, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKL---GNNCVFAPADVTS 67 VA++TG G+GLA A L Q + V+L + + G+A ++L G + F D+ Sbjct: 4 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 63 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVAS 98 + ++ + ++G ++V VN A +A S Sbjct: 64 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKS 94 >1W73-A nrPDB Length = 302 Score = 33.9 bits (76), Expect = 0.077, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 104/259 (40%), Gaps = 23/259 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL----LDLPNSGGEAQAKKLGNNCVFAP 62 S +G VA ITGG +GLG L GA V+ +D+ + E + + GN Sbjct: 23 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 82 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV VQ ++ G ++ +N A S T L T + D+ L Sbjct: 83 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKT------ITDIVL 136 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS-KGGIVGMTLP 181 GT V E+G+ Q+G + + E G SAS K G+ M+ Sbjct: 137 NGT----AFVTLEIGKQLIK--AQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKS 190 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF---LASQVPFPSRLGDPAEYAHLVQ 238 +A + G+R I PG T S + F + ++P RLG E A+L Sbjct: 191 LAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPC-GRLGTVEELANLAA 249 Query: 239 AIIEN--PFLNGEVIRLDG 255 + + ++NG VI+ DG Sbjct: 250 FLCSDYASWINGAVIKFDG 268 >3U4C-A nrPDB Length = 281 Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust. Identities = 60/267 (22%), Positives = 94/267 (35%), Gaps = 41/267 (15%) Query: 12 VAVITGGASGLGLATAERLVGQGASAV-----LLDLPNSGGEAQAKKLGNNCVFAPADVT 66 A + G + G+G A A +L Q S V L ++ + + AK + + D++ Sbjct: 25 TAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMS 84 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHT-----LEDFQRVLDVN 121 + + + GR+DV +N N+ G T +ED Sbjct: 85 DQHTRAGIFQKIESQCGRLDVLIN-----------NIPGGAPDTFDNCNIEDMTATFTQK 133 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + + I+ + M QNE G IIN E S ++ + Sbjct: 134 TVAYIDAIKRASSLMKQNE------FGRIINIVGNLWKEPGANMFTNSMMNAALINASKN 187 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF-----------LASQVPFPSRLGDP 230 I+ LAP I V + PG T E V +AS +P R+G Sbjct: 188 ISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPM-KRVGSA 246 Query: 231 AEYAHLVQ--AIIENPFLNGEVIRLDG 255 E A L A E ++ G+ I DG Sbjct: 247 EETAALAAFLASEEASYITGQQISADG 273 >2YW9-A nrPDB Length = 261 Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust. Identities = 61/223 (27%), Positives = 94/223 (42%), Gaps = 23/223 (10%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVL---LDLPNSGGEAQAKKLGNNCVFAPADV 65 K LV +T S LG A A +L GA L + E A+ LG +F ADV Sbjct: 10 KALVMGVTNQRS-LGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLF-RADV 67 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T ++++ A K FG +D V+ IA A + + +D+ L+V+ Sbjct: 68 TQDEELDALFAGVKEAFGGLDYLVHA--IAFAPREAMEGRYIDTRRQDWLLALEVSAYSL 125 Query: 126 FNVIRLVAGEMGQNEP--DQGGQRGVIINTASVAAFEGQVGQAAYSA-SKGGIVGMTLPI 182 V R + EP +GG G++ T + A E V + A +K + + Sbjct: 126 VAVAR-------RAEPLLREGG--GIV--TLTYYASEKVVPKYNVMAIAKAALEASVRYL 174 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLP--EKVCNFLASQVPF 223 A +L P G+RV I+ G T S+P K+ + +A P Sbjct: 175 AYELGPKGVRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPL 217 >1YQG-A nrPDB Length = 263 Score = 31.2 bits (69), Expect = 0.45, Method: Compositional matrix adjust. Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 5/79 (6%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 M AAC++++ A++ A+GL + T R +G G ++ +PN+ G+ LG + ++ Sbjct: 70 MEAACKNIRTNGALVLSVAAGLSVGTLSRYLG-GTRRIVRVMPNTPGKI---GLGVSGMY 125 Query: 61 APADVTSEKDVQTALALAK 79 A A+V SE D + A + K Sbjct: 126 AEAEV-SETDRRIADRIMK 143 >4EJ6-A nrPDB Length = 370 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 22/131 (16%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 VA++ GG GL RL G A+ V+L + A+++G P S DV Sbjct: 186 VAILGGGVIGLLTVQLARLAG--ATTVILSTRQATKRRLAEEVGATATVDP----SAGDV 239 Query: 72 QTALALAKGKF-GRVDVAVNCAGIAVASKTYN--------------LKKGQTHTLEDFQR 116 A+A G G VDV + CAG+A K L +G+ +E F Sbjct: 240 VEAIAGPVGLVPGGVDVVIECAGVAETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPFDI 299 Query: 117 VL-DVNLMGTF 126 + ++ ++G+F Sbjct: 300 LFRELRVLGSF 310 >4RQU-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 38/82 (46%), Gaps = 6/82 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 VA+ GA GLG A R+ GAS ++ NS QAK+ G P D +K + Sbjct: 194 VAIFGLGAVGLGAAEGARIA--GASRIIGVDFNSKRFDQAKEFGVTECVNPKD--HDKPI 249 Query: 72 QTALALAKGKFGRVDVAVNCAG 93 Q +A G VD +V C G Sbjct: 250 QQVIAEMTD--GGVDRSVECTG 269 >3IP1-A nrPDB Length = 404 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 VI GG +GLA L GAS V+L P+ AK+LG + V P T E V+ Sbjct: 218 VILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDP---TKENFVEA 273 Query: 74 ALALAKG 80 L G Sbjct: 274 VLDYTNG 280 >4Z3K-A nrPDB Length = 275 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 141 PDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGL 200 PD G ++N +S+ A + G A Y A K + +A L +RV+ APG Sbjct: 157 PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGP 214 Query: 201 FGTPL 205 T + Sbjct: 215 LDTDM 219 >4HWK-A nrPDB Length = 288 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 141 PDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGL 200 PD G ++N +S+ A + G A Y A K + +A L +RV+ APG Sbjct: 170 PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGP 227 Query: 201 FGTPL 205 T + Sbjct: 228 LDTDM 232 >1OAA-A nrPDB Length = 259 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 46/201 (22%), Positives = 82/201 (40%), Gaps = 23/201 (11%) Query: 12 VAVITGGASGLGLATA---ERLVGQGASAVLLDLPNSGGEAQAKKLGN-----NCVFAPA 63 V V+TG + G G A A RL+ G+ ++ S ++LG V A A Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 64 DVTSEKDVQTALALAK-----GKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 D+ +E VQ L+ + R+ + N A + SK + + D V Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGF-------LNVNDLAEVN 120 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 + + +++ L +G + + D G ++N +S+ A + G Y A K + Sbjct: 121 NYWALNLTSMLCLTSGTLNAFQ-DSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 179 Query: 179 TLPIARDLAPIGIRVMTIAPG 199 +A + +RV++ APG Sbjct: 180 YQVLAAE--EPSVRVLSYAPG 198 >4LN1-A nrPDB Length = 336 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASA--VLLDLPNSGGEAQAKKLGNNCVFAPA 63 KG+ V+ G +G + A ++ Q + VL+D+ + E +A L + FAPA Sbjct: 25 KGINRVVLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPA 81 >1LU9-A nrPDB Length = 287 Score = 26.9 bits (58), Expect = 9.3, Method: Compositional matrix adjust. Identities = 17/37 (45%), Positives = 22/37 (59%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVL 39 AA SVKG AV+ G +G+ +A L G+GA VL Sbjct: 112 AAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVL 148 >2EFY-A nrPDB Length = 304 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 15/28 (53%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Query: 171 SKGGIVGMTLPIARDLAPIGIRVMTIAP 198 S GGIV L +AR+L P G RV I+P Sbjct: 263 SSGGIVWAALQVARELGP-GKRVACISP 289 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2O23-A nrPDB 309 6e-85 1E3W-A nrPDB 293 5e-80 2PNF-A nrPDB 286 5e-78 3RSH-A nrPDB 276 7e-75 2HQ1-A nrPDB 273 6e-74 2UVD-A nrPDB 272 8e-74 2C07-A nrPDB 272 1e-73 4JRO-A nrPDB 272 1e-73 3OSU-A nrPDB 271 2e-73 5CDY-A nrPDB 269 8e-73 1Q7C-A nrPDB 267 4e-72 3EMK-A nrPDB 264 3e-71 3LYL-A nrPDB 262 8e-71 3F9I-A nrPDB 260 5e-70 3FTP-A nrPDB 259 1e-69 3GRP-A nrPDB 256 5e-69 4BO1-A nrPDB 256 6e-69 3WOH-A nrPDB 255 1e-68 4M8S-A nrPDB 255 1e-68 5ITV-A nrPDB 249 8e-67 3EZL-A nrPDB 247 3e-66 4CQL-A nrPDB 247 5e-66 4NBT-A nrPDB 246 6e-66 4DMM-A nrPDB 245 2e-65 2PH3-A nrPDB 245 2e-65 4K6F-A nrPDB 245 2e-65 3VZS-A nrPDB 244 3e-65 4KMS-A nrPDB 244 3e-65 4CQM-B nrPDB 244 4e-65 4RZH-A nrPDB 242 9e-65 1GEE-A nrPDB 242 1e-64 3AUT-A nrPDB 242 1e-64 4NBV-A nrPDB 239 7e-64 2CDH-G nrPDB 239 8e-64 6NRP-A nrPDB 239 9e-64 2NM0-A nrPDB 238 1e-63 4IIN-A nrPDB 237 3e-63 3OEC-A nrPDB 233 5e-62 5VT6-A nrPDB 233 6e-62 1GEG-A nrPDB 233 7e-62 3O4R-A nrPDB 231 2e-61 5OVL-A nrPDB 230 3e-61 4RZI-B nrPDB 230 5e-61 1NFF-A nrPDB 230 5e-61 5T5Q-A nrPDB 228 1e-60 1AE1-A nrPDB 228 2e-60 2EW8-A nrPDB 228 2e-60 2ZAT-A nrPDB 227 3e-60 5OVJ-A nrPDB 225 1e-59 2AE2-A nrPDB 225 2e-59 4IIV-A nrPDB 223 5e-59 5OJG-A nrPDB 222 1e-58 1UZM-A nrPDB 222 1e-58 3WTC-A nrPDB 222 1e-58 4Z9Y-A nrPDB 221 2e-58 5U9P-A nrPDB 220 4e-58 3RWB-A nrPDB 220 4e-58 3PPI-A nrPDB 219 1e-57 6CI9-A nrPDB 218 1e-57 3WYE-A nrPDB 216 6e-57 2Q2Q-A nrPDB 215 1e-56 1YXM-A nrPDB 215 1e-56 4IS3-A nrPDB 214 2e-56 3UVE-A nrPDB 214 3e-56 2HSD-A nrPDB 212 9e-56 2CFC-A nrPDB 212 9e-56 3T7C-A nrPDB 212 1e-55 3W8F-A nrPDB 211 3e-55 1K2W-A nrPDB 210 4e-55 3V2G-A nrPDB 210 6e-55 1DOH-A nrPDB 210 7e-55 1HXH-A nrPDB 208 2e-54 2X9N-A nrPDB 208 2e-54 3V2H-A nrPDB 207 3e-54 3R3S-A nrPDB 207 3e-54 4E6P-A nrPDB 207 4e-54 5YSS-A nrPDB 206 9e-54 4DBZ-A nrPDB 206 1e-53 2QHX-A nrPDB 205 1e-53 2BFA-A nrPDB 205 2e-53 3A28-C nrPDB 205 2e-53 4HP8-A nrPDB 204 3e-53 5EJ2-A nrPDB 203 8e-53 4MOW-A nrPDB 203 8e-53 1X1T-A nrPDB 202 1e-52 3U5T-A nrPDB 202 1e-52 1P33-A nrPDB 202 2e-52 1AHH-A nrPDB 202 2e-52 2B4Q-A nrPDB 201 3e-52 2GDZ-A nrPDB 200 4e-52 1O5I-A nrPDB 197 5e-51 5B1Y-A nrPDB 195 2e-50 3OIC-A nrPDB 195 2e-50 4AVY-A nrPDB 194 3e-50 4FC7-A nrPDB 192 1e-49 5JS6-A nrPDB 192 2e-49 4TRR-A nrPDB 191 3e-49 3ZV3-A nrPDB 190 5e-49 3GDF-A nrPDB 189 1e-48 2AG5-A nrPDB 188 2e-48 2BGM-A nrPDB 187 4e-48 1H5Q-A nrPDB 187 4e-48 3UN1-A nrPDB 186 6e-48 4CR6-A nrPDB 186 7e-48 3D3W-A nrPDB 186 8e-48 3UF0-A nrPDB 186 9e-48 5IZ4-A nrPDB 185 2e-47 5JY1-A nrPDB 183 6e-47 1BDB-A nrPDB 183 8e-47 1CYD-A nrPDB 181 2e-46 5O3Z-A nrPDB 179 1e-45 4RGB-A nrPDB 177 4e-45 2FWM-X nrPDB 176 6e-45 4DA9-A nrPDB 175 1e-44 3V8B-A nrPDB 174 3e-44 3OML-A nrPDB 171 2e-43 4EGF-A nrPDB 168 2e-42 3PXX-A nrPDB 167 5e-42 4GKB-A nrPDB 166 8e-42 5ILO-A nrPDB 161 3e-40 3RKU-A nrPDB 158 2e-39 2NWQ-A nrPDB 158 2e-39 4HBG-A nrPDB 150 8e-37 4DRY-A nrPDB 145 2e-35 1A27-A nrPDB 136 8e-33 6CGE-A nrPDB 135 2e-32 2DKN-A nrPDB 129 2e-30 1B15-A nrPDB 128 3e-30 1MG5-A nrPDB 119 2e-27 3O26-A nrPDB 117 4e-27 3U9L-A nrPDB 111 4e-25 5LCX-A nrPDB 99 1e-21 Sequences not found previously or not previously below threshold: 3U4C-A nrPDB 146 1e-35 1W73-A nrPDB 141 2e-34 2P91-A nrPDB 135 2e-32 2YW9-A nrPDB 129 8e-31 3KZV-A nrPDB 128 4e-30 3E9N-A nrPDB 126 1e-29 2HRB-A nrPDB 121 3e-28 3OIG-A nrPDB 117 6e-27 5L51-A nrPDB 114 4e-26 4M89-A nrPDB 114 5e-26 5PGZ-A nrPDB 111 2e-25 5YCX-A nrPDB 111 3e-25 1N5D-A nrPDB 111 3e-25 3DWF-A nrPDB 111 4e-25 5KOI-A nrPDB 110 6e-25 4NR0-A nrPDB 109 1e-24 3BHI-A nrPDB 108 2e-24 5I9N-A nrPDB 107 4e-24 4ZJU-A nrPDB 107 6e-24 5CFZ-A nrPDB 106 7e-24 1SNY-A nrPDB 106 1e-23 3GRK-A nrPDB 106 1e-23 4JQC-A nrPDB 105 2e-23 3UCF-A nrPDB 105 2e-23 5TF4-A nrPDB 105 2e-23 1FJH-A nrPDB 103 1e-22 3K2E-A nrPDB 101 3e-22 4ALL-A nrPDB 100 5e-22 4J3F-A nrPDB 98 4e-21 4HWK-A nrPDB 93 8e-20 4Z3K-A nrPDB 93 9e-20 4NK4-A nrPDB 91 4e-19 2PD3-A nrPDB 89 2e-18 4Q9N-A nrPDB 88 4e-18 1OAA-A nrPDB 88 5e-18 5TQV-A nrPDB 88 5e-18 5WQO-A nrPDB 87 9e-18 2NTV-A nrPDB 86 1e-17 4OYR-A nrPDB 83 1e-16 1ENP-A nrPDB 80 1e-15 2O2S-A nrPDB 74 7e-14 2PTG-A nrPDB 70 1e-12 3F4B-A nrPDB 68 4e-12 3SLK-A nrPDB 60 9e-10 4LIS-A nrPDB 58 6e-09 3ORF-A nrPDB 55 4e-08 2O2Y-A nrPDB 52 2e-07 1DIR-A nrPDB 50 8e-07 1UDA-A nrPDB 50 8e-07 1OOE-A nrPDB 49 1e-06 1Z45-A nrPDB 49 2e-06 6BWL-A nrPDB 49 2e-06 3RFT-A nrPDB 48 3e-06 3ENK-A nrPDB 48 3e-06 2PK3-A nrPDB 48 6e-06 4R1T-A nrPDB 46 1e-05 2Q1W-A nrPDB 43 2e-04 4G5H-A nrPDB 43 2e-04 5N2I-A nrPDB 42 2e-04 1I3M-A nrPDB 42 3e-04 2HUN-A nrPDB 41 5e-04 1VL0-A nrPDB 40 8e-04 3VPX-A nrPDB 40 9e-04 1LU9-A nrPDB 40 0.001 1BXK-A nrPDB 40 0.001 4J6F-A nrPDB 40 0.001 1GY8-A nrPDB 40 0.001 2GN9-A nrPDB 39 0.001 1R66-A nrPDB 39 0.001 5INT-A nrPDB 39 0.002 5K1S-A nrPDB 39 0.002 6ACF-A nrPDB 39 0.002 2Z95-A nrPDB 39 0.002 2PZM-A nrPDB 38 0.004 4PVC-A nrPDB 38 0.004 4K28-A nrPDB 38 0.005 4EUF-A nrPDB 38 0.005 2C20-A nrPDB 38 0.006 6DEB-A nrPDB 38 0.006 5F5N-A nrPDB 38 0.006 6G2J-P nrPDB 37 0.007 5ENV-A nrPDB 37 0.008 1WVG-A nrPDB 37 0.009 2DFV-A nrPDB 37 0.010 4A10-A nrPDB 37 0.011 4EJ6-A nrPDB 36 0.012 4J2O-A nrPDB 36 0.013 3IP1-A nrPDB 36 0.014 6GCS-E nrPDB 36 0.016 3OND-A nrPDB 36 0.016 1OC2-A nrPDB 36 0.018 2HK7-A nrPDB 35 0.035 2EER-A nrPDB 35 0.038 6ACQ-A nrPDB 35 0.039 4KTT-E nrPDB 34 0.043 1KEU-A nrPDB 34 0.045 1U3W-A nrPDB 34 0.045 1O89-A nrPDB 34 0.047 2EXX-A nrPDB 34 0.054 1ZZE-A nrPDB 34 0.056 4WOK-A nrPDB 34 0.058 2NNL-D nrPDB 34 0.063 5YWN-A nrPDB 34 0.065 4UUP-A nrPDB 34 0.066 1YB5-A nrPDB 34 0.086 5GUP-L nrPDB 33 0.12 1EE2-A nrPDB 33 0.13 2Q4B-A nrPDB 33 0.16 4KDR-A nrPDB 33 0.18 3DFZ-A nrPDB 33 0.19 4KDC-A nrPDB 33 0.20 2C54-A nrPDB 33 0.21 3PEF-A nrPDB 32 0.22 2VN8-A nrPDB 32 0.25 4KUG-A nrPDB 32 0.28 3R9I-A nrPDB 32 0.30 4J90-A nrPDB 32 0.30 3BIC-A nrPDB 32 0.31 1JPH-A nrPDB 32 0.35 3NJ4-A nrPDB 31 0.38 3FBG-A nrPDB 31 0.39 4DGK-A nrPDB 31 0.39 1HSO-A nrPDB 31 0.41 4XRR-A nrPDB 31 0.42 5JXW-A nrPDB 31 0.42 3COS-A nrPDB 31 0.46 6H0D-A nrPDB 31 0.47 3R7T-A nrPDB 31 0.48 3DMF-A nrPDB 31 0.48 1E3J-A nrPDB 31 0.53 3SXP-A nrPDB 31 0.54 5B6K-A nrPDB 31 0.54 6C55-A nrPDB 31 0.56 3F6S-A nrPDB 31 0.56 3WJN-A nrPDB 31 0.65 6BMQ-A nrPDB 31 0.68 4B1B-A nrPDB 31 0.68 7REQ-A nrPDB 31 0.77 3ZU2-A nrPDB 30 0.80 3EXA-A nrPDB 30 0.81 4XFD-A nrPDB 30 0.84 2YQ5-A nrPDB 30 0.84 4BKP-A nrPDB 30 0.84 6BI4-A nrPDB 30 0.89 2WEK-A nrPDB 30 0.90 1HSZ-A nrPDB 30 0.90 3N58-A nrPDB 30 0.92 3VR3-A nrPDB 30 0.96 4E0B-A nrPDB 30 0.97 1JAY-A nrPDB 30 0.97 3LK7-A nrPDB 30 0.98 1MLD-A nrPDB 30 1.0 5GXF-A nrPDB 30 1.1 4EJ0-A nrPDB 30 1.2 2GAS-A nrPDB 30 1.3 3HZZ-A nrPDB 30 1.3 4WLE-A nrPDB 30 1.3 2BC1-A nrPDB 30 1.3 1HYE-A nrPDB 30 1.4 2Y6O-A nrPDB 29 1.4 4B4V-A nrPDB 29 1.6 2GGS-A nrPDB 29 1.6 3SC6-A nrPDB 29 1.6 1CDO-A nrPDB 29 1.6 6GBN-A nrPDB 29 1.7 1NHQ-A nrPDB 29 1.7 3PII-A nrPDB 29 1.8 4GBJ-A nrPDB 29 1.8 1IE3-A nrPDB 29 1.9 4PZE-A nrPDB 29 1.9 1EDZ-A nrPDB 29 2.0 2OHJ-A nrPDB 29 2.0 6CAU-A nrPDB 29 2.0 3H0K-A nrPDB 29 2.1 1YXY-A nrPDB 29 2.1 2Q4W-A nrPDB 29 2.4 4NFY-A nrPDB 29 2.4 3S8M-A nrPDB 29 2.5 3DC2-A nrPDB 29 2.6 4TSK-A nrPDB 29 2.6 3MMP-A nrPDB 29 2.6 1X74-A nrPDB 29 2.6 1DB3-A nrPDB 29 2.7 4A5O-A nrPDB 29 2.8 2JLA-A nrPDB 29 2.9 1P0F-A nrPDB 29 2.9 5BN5-A nrPDB 29 2.9 5KXJ-A nrPDB 28 3.1 5UZH-A nrPDB 28 3.2 1QQV-A nrPDB 28 3.3 1KGZ-A nrPDB 28 3.4 4BKO-A nrPDB 28 3.5 2X86-A nrPDB 28 3.5 2R5U-A nrPDB 28 3.7 4B4O-A nrPDB 28 3.8 5TC4-A nrPDB 28 4.1 3X2F-A nrPDB 28 4.2 3DQQ-A nrPDB 28 4.3 6APE-A nrPDB 28 4.4 5ZJN-A nrPDB 28 4.4 1UUF-A nrPDB 28 4.4 3M2P-A nrPDB 28 4.6 2IUU-A nrPDB 28 4.8 4Y4N-A nrPDB 28 4.9 4W5U-B nrPDB 28 5.2 5T57-A nrPDB 28 5.4 4R16-A nrPDB 28 5.4 2IUT-A nrPDB 28 5.6 4P2F-A nrPDB 28 5.7 4D3S-A nrPDB 28 6.1 3JTJ-A nrPDB 28 6.3 2D0I-A nrPDB 27 6.9 4A26-A nrPDB 27 7.4 3IGS-A nrPDB 27 7.4 4WEQ-A nrPDB 27 7.4 2DQ4-A nrPDB 27 7.8 4PC7-C nrPDB 27 8.0 4AP9-A nrPDB 27 8.1 3IC6-A nrPDB 27 8.3 3HDH-A nrPDB 27 8.7 6MVR-A nrPDB 27 8.9 5Y77-A nrPDB 27 9.1 4P2M-A nrPDB 27 9.2 5UOG-A nrPDB 27 9.4 4Z6K-A nrPDB 27 9.4 3DDL-A nrPDB 27 10.0 >2O23-A nrPDB Length = 265 Score = 309 bits (793), Expect = 6e-85, Method: Composition-based stats. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF Sbjct: 3 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 62 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV Sbjct: 63 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 122 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 123 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 182 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI Sbjct: 183 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 242 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 243 IENPFLNGEVIRLDGAIRMQP 263 >1E3W-A nrPDB Length = 261 Score = 293 bits (751), Expect = 5e-80, Method: Composition-based stats. Identities = 228/261 (87%), Positives = 245/261 (93%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 MAAA RSVKGLVAVITGGASGLGL+TA+RLVGQGA+AVLLD+PNS GE +AKKLG NC+F Sbjct: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 APA+VTSEK+VQ AL LAK KFGR+DVAVNCAGIAVA KTY+ KK Q HTLEDFQRV++V Sbjct: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL+GTFNVIRLVAG MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 PIARDLAPIGIRV+TIAPGLF TPLLT+LP+ V NFLASQVPFPSRLGDPAEYAHLVQ + Sbjct: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 241 IENPFLNGEVIRLDGAIRMQP 261 >2PNF-A nrPDB Length = 248 Score = 286 bits (733), Expect = 5e-78, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 126/257 (49%), Gaps = 19/257 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFAP 62 ++G V+++TG G+G A AE+L G++ ++ +A A+++ G Sbjct: 4 KLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVE 63 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 ++ SE+ + A +D+ VN AGI + +L D++ VL VNL Sbjct: 64 MNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRM------SLLDWEEVLKVNL 117 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 GTF V + +M + + G I+N +SV F G VGQ YS +K G++G T + Sbjct: 118 TGTFLVTQNSLRKMIKQ------RWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSL 171 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 A++LAP + V +APG T + L E++ Q+P R G P E A++V + Sbjct: 172 AKELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPL-GRFGSPEEVANVVLFLCS 230 Query: 243 --NPFLNGEVIRLDGAI 257 ++ GEVI ++G + Sbjct: 231 ELASYITGEVIHVNGGM 247 >3RSH-A nrPDB Length = 251 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 134/255 (52%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 +++G VA++TG + G+G A AE L +GA + SG +A + LG+N +VT Sbjct: 9 NLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVT 68 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + + ++ L +FG VD+ VN AGI + +K+ E++ +++ NL F Sbjct: 69 NPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKE------EEWSDIMETNLTSIF 122 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + ++G IIN SV G GQA Y+A+K G++G T +AR++ Sbjct: 123 RLSKAVLRGMMKK------RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREV 176 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENP 244 A G+ V T+APG T + +L ++ +QVP RLGDP E A V + E Sbjct: 177 ASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVP-AGRLGDPREIASAVAFLASPEAA 235 Query: 245 FLNGEVIRLDGAIRM 259 ++ GE + ++G + M Sbjct: 236 YITGETLHVNGGMYM 250 >2HQ1-A nrPDB Length = 247 Score = 273 bits (698), Expect = 6e-74, Method: Composition-based stats. Identities = 87/259 (33%), Positives = 134/259 (51%), Gaps = 19/259 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSG-GEAQAKKL---GNNCVFAP 62 +KG A++TG + GLG A A +L GA+ VL P S +A A++ G N V A Sbjct: 2 QLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAK 61 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV + +DV+ + A FGR+D+ VN AGI + + + +D+ VL+ NL Sbjct: 62 GDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSE------KDWDDVLNTNL 115 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + V+ M + + G IIN S+A G GQA Y+ASK G++G T I Sbjct: 116 KSAYLCTKAVSKIMLKQ------KSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSI 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 A++ A GI +APG+ T + LP+KV + +P R G P E A++V + Sbjct: 170 AKEFAAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPL-KRFGTPEEVANVVGFLAS 228 Query: 243 NP--FLNGEVIRLDGAIRM 259 + ++ G+VI +DG + M Sbjct: 229 DDSNYITGQVINIDGGLVM 247 >2UVD-A nrPDB Length = 246 Score = 272 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 127/258 (49%), Gaps = 19/258 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCVFAPA 63 +KG VA++TG + G+G A A L QGA+ V+ N + KKLG++ + A Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV + +DV + FG+VD+ VN AG+ + +K+ E++ V++ NL Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKE------EEWDTVINTNLK 115 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F + V+ M + + G I+N ASV G GQA Y A+K G++G+T A Sbjct: 116 GVFLCTKAVSRFMMRQ------RHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSA 169 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 ++LA I V IAPG T + L E + + +P G+ + A+ V + Sbjct: 170 KELASRNITVNAIAPGFIATDMTDVLDENIKAEMLKLIPAAQ-FGEAQDIANAVTFFASD 228 Query: 244 --PFLNGEVIRLDGAIRM 259 ++ G+ + +DG + M Sbjct: 229 QSKYITGQTLNVDGGMVM 246 >2C07-A nrPDB Length = 285 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 120/255 (47%), Gaps = 18/255 (7%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAPADV 65 + VA++TG G+G A+ L + + + ++ + K G DV Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + ++++ + + VD+ VN AGI + +K ++++ VL NL Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKN------DEWEDVLRTNLNSL 156 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + ++ M N + G IIN +S+ G VGQA YS+SK G++G T +A++ Sbjct: 157 FYITQPISKRMINN------RYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKE 210 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP- 244 LA I V IAPG + + + E++ + S +P R+G P E A+L + + Sbjct: 211 LASRNITVNAIAPGFISSDMTDKISEQIKKNIISNIP-AGRMGTPEEVANLACFLSSDKS 269 Query: 245 -FLNGEVIRLDGAIR 258 ++NG V +DG + Sbjct: 270 GYINGRVFVIDGGLS 284 >4JRO-A nrPDB Length = 271 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 83/263 (31%), Positives = 130/263 (49%), Gaps = 19/263 (7%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAK---KLGNNC 58 + +++G VAV+TGG+ G+G A L +GA+ + E AK + G Sbjct: 22 SNAMTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEV 81 Query: 59 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 A+V +DV A +FGRVD+ VN AGI + +K+ +++ V+ Sbjct: 82 EAMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKE------DEWDDVI 135 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 ++NL GTF + V+ M + + G IIN ASV G GQA Y ASK G++G+ Sbjct: 136 NINLKGTFLCTKAVSRTMMKQ------RAGKIINMASVVGLIGNAGQANYVASKAGVIGL 189 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 T AR+LAP GI V +APG T + L EK + +Q+P G + A+ V Sbjct: 190 TKTTARELAPRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQIPL-GAYGTTEDIANAVL 248 Query: 239 AIIEN--PFLNGEVIRLDGAIRM 259 + + ++ G+ + +DG + M Sbjct: 249 FLASDASKYITGQTLSVDGGMVM 271 >3OSU-A nrPDB Length = 246 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 69/255 (27%), Positives = 123/255 (48%), Gaps = 19/255 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDL----PNSGGEAQAKKLGNNCVFAPADVT 66 A++TG + G+G + A +L +G + + + K G + A+V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 +V+ + +FG +DV VN AGI + +K+ +++ V+D NL G F Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKE------QEWDDVIDTNLKGVF 118 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N I+ +M + + G IIN +SV G GQA Y A+K G++G+T AR+L Sbjct: 119 NCIQKATPQMLRQ------RSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAAREL 172 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--P 244 A GI V +APG + + +L +++ + +Q+P R G + A+ V + + Sbjct: 173 ASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLA-RFGQDTDIANTVAFLASDKAK 231 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ I ++G + M Sbjct: 232 YITGQTIHVNGGMYM 246 >5CDY-A nrPDB Length = 244 Score = 269 bits (689), Expect = 8e-73, Method: Composition-based stats. Identities = 79/255 (30%), Positives = 128/255 (50%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 S +G +A++TG + G+G A AE LV +GA + G EA + LG N +V Sbjct: 2 SFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVV 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + T LA + +FG VD+ VN AGI + +K +++Q ++D NL F Sbjct: 62 DPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKD------DEWQDIIDTNLTSVF 115 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + + G II SV G GQ Y+A+K G++G + +AR++ Sbjct: 116 RLSKAVMRAMMKK------RFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREV 169 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--P 244 A GI V +APG T + +L + + +QVP +RLGD E A V + + Sbjct: 170 ASRGITVNVVAPGFIETDMTRTLTDDQRAGILAQVP-ANRLGDAKEIASAVAFLASDEAS 228 Query: 245 FLNGEVIRLDGAIRM 259 +++GE + ++G + M Sbjct: 229 YISGETLHVNGGMYM 243 >1Q7C-A nrPDB Length = 244 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 127/255 (49%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + +G +A++TG + G+G A AE L +GA + +G +A + LG N +VT Sbjct: 2 NFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVT 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 +++ L + +FG VD+ VN AGI + +K E++ +++ NL F Sbjct: 62 DPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKD------EEWNDIIETNLSSVF 115 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + + G II SV G GQA ++A+K G++G + +AR++ Sbjct: 116 RLSKAVMRAMMKK------RHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREV 169 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--P 244 A GI V +APG T + +L + + +QVP RLG E A+ V + + Sbjct: 170 ASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVP-AGRLGGAQEIANAVAFLASDEAA 228 Query: 245 FLNGEVIRLDGAIRM 259 ++ GE + ++G + M Sbjct: 229 YITGETLHVNGGMYM 243 >3EMK-A nrPDB Length = 246 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 119/258 (46%), Gaps = 15/258 (5%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 + + G A++TG GLG A A L QGA L + A +LG PA Sbjct: 1 SMFDLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPA 60 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 +++ + V+ A+ + G VD+ VN AGI + ED+ VL VNL Sbjct: 61 NLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSD------EDWDAVLTVNLT 114 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 FN+ R + M + + G IIN S+ G GQA Y ASK G++G + +A Sbjct: 115 SVFNLTRELTHPMMRR------RNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLA 168 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 +++A + V IAPG + + L EK + + +P R+G A+ A V + + Sbjct: 169 QEIASRNVTVNCIAPGFIESAMTGKLNEKQKDAIMGNIPM-KRMGVGADIAAAVVYLASD 227 Query: 244 --PFLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 228 EAAYVTGQTLHVNGGMAM 245 >3LYL-A nrPDB Length = 247 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 63/258 (24%), Positives = 121/258 (46%), Gaps = 18/258 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAPA 63 S+ VA++TG + G+G A L +GA+ V + E K+ G Sbjct: 2 SLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVL 61 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 +++ + +Q A K + +D+ VN AGI + + + +++Q V++ NL Sbjct: 62 NISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSE------DEWQSVINTNLS 115 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F + + M + + G II+ SV G GQ Y A+K G++G + +A Sbjct: 116 SIFRMSKECVRGMMKK------RWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLA 169 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII-- 241 ++A I V +APG T + L ++ +F+A+++P ++G+P + A V + Sbjct: 170 YEVASRNITVNVVAPGFIATDMTDKLTDEQKSFIATKIP-SGQIGEPKDIAAAVAFLASE 228 Query: 242 ENPFLNGEVIRLDGAIRM 259 E ++ G+ + ++G + M Sbjct: 229 EAKYITGQTLHVNGGMYM 246 >3F9I-A nrPDB Length = 249 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 64/255 (25%), Positives = 119/255 (46%), Gaps = 19/255 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G ++ITG +SG+G A A L G+ ++ ++ L +N ++ Sbjct: 11 DLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLA 70 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 ++++ ++ +D+ V AGI + +K +DF +V+D+NL F Sbjct: 71 NKEECSNLISKTSN----LDILVCNAGITSDTLAIRMKD------QDFDKVIDINLKANF 120 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + R +M Q + G IIN +S+ G GQA Y ASK G++GMT ++ ++ Sbjct: 121 ILNREAIKKMIQK------RYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEV 174 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NP 244 A GI V +APG + + L EK + ++P + G P + A+ V + Sbjct: 175 ATRGITVNAVAPGFIKSDMTDKLNEKQREAIVQKIPLGT-YGIPEDVAYAVAFLASNNAS 233 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 234 YITGQTLHVNGGMLM 248 >3FTP-A nrPDB Length = 270 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 75/262 (28%), Positives = 121/262 (46%), Gaps = 18/262 (6%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV 59 + +++ VA++TG + G+G A A L +GA + +G E A K+ G Sbjct: 21 SMDKTLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGR 80 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 A +V V + +FG ++V VN AGI +K +++ V+D Sbjct: 81 GAVLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKD------DEWDAVID 134 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL F + R V M + + G I+N SV G GQ Y+A+K G+ GMT Sbjct: 135 TNLKAVFRLSRAVLRPMMK------ARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMT 188 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 +AR++ GI V +APG T + LP++ L +Q+P RLG P + AH V Sbjct: 189 RALAREIGSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPL-GRLGSPEDIAHAVAF 247 Query: 240 IIE--NPFLNGEVIRLDGAIRM 259 + ++ G + ++G + M Sbjct: 248 LASPQAGYITGTTLHVNGGMFM 269 >3GRP-A nrPDB Length = 266 Score = 256 bits (655), Expect = 5e-69, Method: Composition-based stats. Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 15/260 (5%) Query: 2 AAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA 61 + + G A++TG G+G A A QGA L + A LG + Sbjct: 19 PGSMFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVF 78 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 A+++ K ++ +A+ + +D+ VN AGI ++ +D+ VL VN Sbjct: 79 SANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQD------QDWDDVLAVN 132 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L + R + M + + G IIN S+ G GQ Y A+K G++G + Sbjct: 133 LTAASTLTRELIHSMMRR------RYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKA 186 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEY--AHLVQA 239 +A+++A I V IAPG + + L EK + + +P R+G E A + A Sbjct: 187 LAQEIASRNITVNCIAPGFIKSAMTDKLNEKQKEAIMAMIPM-KRMGIGEEIAFATVYLA 245 Query: 240 IIENPFLNGEVIRLDGAIRM 259 E +L G+ + ++G + M Sbjct: 246 SDEAAYLTGQTLHINGGMAM 265 >4BO1-A nrPDB Length = 269 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 118/258 (45%), Gaps = 18/258 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPA 63 S++G VA++TG + G+G A A L GA + SG E A+ L G Sbjct: 24 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL 83 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV+S++ V L + G+ + VN AGI + +K +++ V++ NL Sbjct: 84 DVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKD------DEWFDVVNTNLN 137 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + + V M + + G IIN SV G GQ Y+A+K G+ G T +A Sbjct: 138 SLYRLSKAVLRGMTK------ARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALA 191 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 R++ I V +APG T + LPE L Q+P RLG E A +V + + Sbjct: 192 REVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPL-GRLGQAEEIAKVVGFLASD 250 Query: 244 --PFLNGEVIRLDGAIRM 259 ++ G + ++G + M Sbjct: 251 GAAYVTGATVPVNGGMYM 268 >3WOH-A nrPDB Length = 251 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 124/258 (48%), Gaps = 21/258 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLL----DLPNSGGEAQAKKLGNNCVFAPA 63 + G VA++TGG+ GLG A A RL GA+ ++ D + + ++LG Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV+ + V + G VD+ VN AGI ++K ED+ V++ NL Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKD------EDYDAVMNTNLK 122 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F I+ + + G IIN +SV+ G GQA Y+++K G++G+T IA Sbjct: 123 GAFLFIKACYFGFIRK------RSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIA 176 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII-- 241 ++LA +R +APGL T + L + VP R G P E A LV + Sbjct: 177 KELAERNVRCNAVAPGLIATDMTQDLVDDSKR--LDPVPM-RRFGRPDEVAGLVAFLAGD 233 Query: 242 ENPFLNGEVIRLDGAIRM 259 E+ ++ G+V+ +DG + M Sbjct: 234 ESSYITGQVVCVDGGMAM 251 >4M8S-A nrPDB Length = 248 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 68/259 (26%), Positives = 122/259 (47%), Gaps = 16/259 (6%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN-NCVFAP 62 + + + G +A++TG + G+G A A+ L GA + SG A +++L Sbjct: 2 STQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRV 61 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 + + V+ +A + FG++D+ VN AGI + +K+ E++ ++ VNL Sbjct: 62 LNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKE------EEWDDIMQVNL 115 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F + V M + + G IIN SV G GQ Y+A+K G++G + + Sbjct: 116 KSVFRASKAVLRGMMKQ------RAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSM 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 AR++ GI V +APG T + +LPE+ +Q R GD + A V + Sbjct: 170 AREVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTAL-GRFGDAQDIADAVLFLAS 228 Query: 243 N--PFLNGEVIRLDGAIRM 259 + ++ G+ + ++G + M Sbjct: 229 DQAKYITGQTLHVNGGMLM 247 >5ITV-A nrPDB Length = 255 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 84/268 (31%), Positives = 125/268 (46%), Gaps = 24/268 (8%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN-NCVFAP 62 ++ +ITGGASG+G A + +GQ A+ V+ D+ + GEA +K N F Sbjct: 1 MIMNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQ 60 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 D+T E Q A+ A FG +DV +N AGI + + + ++ L D+ +VL VNL Sbjct: 61 TDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEME------LSDWNKVLQVNL 114 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G F + + M +G IINT SV AY+ASKGG++ +T + Sbjct: 115 TGMFLMSKHALKHM------LAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSM 168 Query: 183 ARDLAPIGIRVMTIAPGLFGTPL--------LTSLPEKVCNFLASQVPFPSRLGDPAEYA 234 A D A IRV + PG+ TPL E++ A P RLG P E A Sbjct: 169 AVDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLL-RLGKPEEIA 227 Query: 235 HLVQAIIEN--PFLNGEVIRLDGAIRMQ 260 +++ + + ++ G I DG Q Sbjct: 228 NVMLFLASDLSSYMTGSAITADGGYTAQ 255 >3EZL-A nrPDB Length = 256 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 80/256 (31%), Positives = 119/256 (46%), Gaps = 19/256 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNS----GGEAQAKKLGNNCVFAPADVT 66 +A +TGG G+G + +RL G V PNS K LG + + +V Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVG 73 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + A K + G +DV VN AGI + T ED+Q V+D NL F Sbjct: 74 DWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKM------TREDWQAVIDTNLTSLF 127 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV + V M + G IIN +SV +GQ GQ YS +K GI G T+ +A+++ Sbjct: 128 NVTKQVIDGMVER------GWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEV 181 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENP 244 A G+ V T++PG GT ++ ++ V + + +P RLG P E +V + E+ Sbjct: 182 ATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPV-RRLGSPDEIGSIVAWLASEESG 240 Query: 245 FLNGEVIRLDGAIRMQ 260 F G L+G + M Sbjct: 241 FSTGADFSLNGGLHMG 256 >4CQL-A nrPDB Length = 261 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 81/267 (30%), Positives = 131/267 (49%), Gaps = 25/267 (9%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN--------- 56 ++ +A++TG SG+G A + RL G+GA+ DL + + + LG Sbjct: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 Query: 57 -NCVFAPADVTSEKDVQTALALAKGKFGRV-DVAVNCAGIAVASKTYNLKKGQTHTLEDF 114 N ADV+ + + L + F R V V+CAGI ++ + +D+ Sbjct: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE------DDW 120 Query: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174 +V+ VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G Sbjct: 121 DKVIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAG 175 Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYA 234 ++G+T AR+L GIR ++ PG TP+ +P+KV + + +P LGDP + A Sbjct: 176 VIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVA 234 Query: 235 HLVQAIIE--NPFLNGEVIRLDGAIRM 259 +V + + ++ G + + G + M Sbjct: 235 DVVAFLASEDSGYITGTSVEVTGGLFM 261 >4NBT-A nrPDB Length = 240 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 84/259 (32%), Positives = 131/259 (50%), Gaps = 23/259 (8%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + ++G VAVITGGA GLG A A +GA + DL + N + Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD------LTYSHPNVEGMYLN 54 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 VT V+ K+G++D+ VN AGI + T + T + V+DVNL G Sbjct: 55 VTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKM------TEAQWDAVIDVNLKG 108 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 FN+ RLV +M Q G IIN +SV G +GQA Y+A+K G++G+T+ A+ Sbjct: 109 VFNLTRLVGPQM------QTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAK 162 Query: 185 DLAPIG--IRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 + A G +RV IAPG T +L ++P+ + + A+ +RLG P E A + + Sbjct: 163 EFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAALT-MLNRLGQPEEIAKVALFLAS 221 Query: 243 N--PFLNGEVIRLDGAIRM 259 + ++ G+ I ++G +R+ Sbjct: 222 DDASYVTGQTINVNGGMRL 240 >4DMM-A nrPDB Length = 269 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 83/259 (32%), Positives = 128/259 (49%), Gaps = 23/259 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA----PA 63 + +A++TG + G+G A A L GA + ++G + A Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKA 85 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV+ E +V+ A ++GR+DV VN AGI + +K+ +D+Q VLD+NL Sbjct: 86 DVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKR------DDWQSVLDLNLG 139 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F R A M + + G IIN ASV G GQA YSA+K G++G+T +A Sbjct: 140 GVFLCSRAAAKIMLKQ------RSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVA 193 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 ++LA GI V +APG T + + L L +P R G+ AE A +V+ + + Sbjct: 194 KELASRGITVNAVAPGFIATDMTSEL---AAEKLLEVIPL-GRYGEAAEVAGVVRFLAAD 249 Query: 244 P---FLNGEVIRLDGAIRM 259 P ++ G+VI +DG + M Sbjct: 250 PAAAYITGQVINIDGGLVM 268 >2PH3-A nrPDB Length = 245 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 70/255 (27%), Positives = 108/255 (42%), Gaps = 20/255 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN-----CVFAPADV 65 A+ITG + G+G A A RL G + + N + + A++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + + A G +D VN AGI + +K ED++ VL+ NL Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKD------EDWEAVLEANLSAV 115 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F R M + + G I+N SV G GQA Y ASK G++G T +A++ Sbjct: 116 FRTTREAVKLMMK------ARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKE 169 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--N 243 A GI V +APG T + LP++V Q+P R G P E A V ++ Sbjct: 170 YAQRGITVNAVAPGFIETEMTERLPQEVKEAYLKQIP-AGRFGRPEEVAEAVAFLVSEKA 228 Query: 244 PFLNGEVIRLDGAIR 258 ++ G+ + +DG + Sbjct: 229 GYITGQTLCVDGGLT 243 >4K6F-A nrPDB Length = 255 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 79/260 (30%), Positives = 119/260 (45%), Gaps = 20/260 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCVFAPA 63 + +AV+TGG GLG A + RL G V+ PN+ G + G P Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPV 68 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV Q + G VD+ VN AGI L K ++ V+ NL Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKV------NWDAVIRTNLD 122 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 FN+ + V M + G I+N +SV +G VGQ Y+A+K G+ G T +A Sbjct: 123 SVFNMTKPVCDGMVER------GWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLA 176 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCN-FLASQVPFPSRLGDPAEYAHLVQAII- 241 ++A G+ V T++PG T ++T++P+ + + + Q+P RLG P E A LV + Sbjct: 177 LEIARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIP-AGRLGKPEEVAALVAYLCS 235 Query: 242 -ENPFLNGEVIRLDGAIRMQ 260 E F+ G I ++G M Sbjct: 236 EEAGFVTGSNIAINGGQHMH 255 >3VZS-A nrPDB Length = 257 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 120/256 (46%), Gaps = 19/256 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNS----GGEAQAKKLGNNCVFAPADVT 66 +A +TGG G+G A +RL G V PNS Q K LG + + + +V Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 +TA K + G VDV +N AGI + T D+ V+D NL F Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKM------TRADWDAVIDTNLTSLF 128 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV + V M G I+N +SV +GQ GQ YS +K G+ G T+ +A+++ Sbjct: 129 NVTKQVIDGMADR------GWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEV 182 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI--IENP 244 A G+ V T++PG T ++ ++ + V + + + +P RLG P E A + + E+ Sbjct: 183 ATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPV-KRLGLPEEIASICAWLSSEESG 241 Query: 245 FLNGEVIRLDGAIRMQ 260 F G L+G + M Sbjct: 242 FSTGADFSLNGGLHMG 257 >4KMS-A nrPDB Length = 249 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 80/263 (30%), Positives = 127/263 (48%), Gaps = 19/263 (7%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKLGNNCV 59 MA +A++TGG G+G ATA L +G + V N + +K G Sbjct: 1 MAHHHHHHMSEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTK 60 Query: 60 FAPADVTSEKDVQTALALAKGKFGR-VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 +V ++ + A+ + +F + V + VN AGI + + + +D+ V+ Sbjct: 61 C--WNVADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRM------SHQDWNDVI 112 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 +VNL FN+ V +M + G I+N +S+ A GQVGQ YSA+K GI+G Sbjct: 113 NVNLNSCFNMSSSVMEQM------RNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGF 166 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 T +AR+ A I V IAPG T ++ ++PE V + + +P RLG P E A V Sbjct: 167 TKALARETASKNITVNCIAPGYIATEMVGAVPEDVLAKIINSIP-KKRLGQPEEIARAVA 225 Query: 239 AIIE--NPFLNGEVIRLDGAIRM 259 +++ F+ GE I ++G M Sbjct: 226 FLVDENAGFITGETISINGGHNM 248 >4CQM-B nrPDB Length = 244 Score = 244 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 78/251 (31%), Positives = 119/251 (47%), Gaps = 16/251 (6%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 V + GG+ G+G A A+ + +G ++ G +A A LG + + DV E Sbjct: 8 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 67 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 DVQ + GRV+ VN AGI K ED L NL+G+ Sbjct: 68 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKT------EDMVSQLHTNLLGSMLT 121 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A Sbjct: 122 CKAAMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVAR 175 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNG 248 IRV +APG T + L E+ L +P R G+ E AH V ++E+P++ G Sbjct: 176 KKIRVNVVAPGFVHTDMTKDLKEE---HLKKNIPL-GRFGETIEVAHAVVFLLESPYITG 231 Query: 249 EVIRLDGAIRM 259 V+ +DG +++ Sbjct: 232 HVLVVDGGLQL 242 >4RZH-A nrPDB Length = 247 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 80/263 (30%), Positives = 126/263 (47%), Gaps = 23/263 (8%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCVF 60 ++ VA++TG + G+G ATA L G V+ +S A+ G + Sbjct: 1 MTALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIA 60 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 A+V + +V + KF R+DV VN AGI + +K LED+Q V+D+ Sbjct: 61 VQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMK------LEDWQAVIDL 114 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL G F + V+ M + + G IIN SVA G GQA YSA+K G++G T Sbjct: 115 NLTGVFLCTKAVSKLMLKQ------KSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTK 168 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 +A++LA G+ V +APG T + +L + + +P R G P E A ++ + Sbjct: 169 TVAKELASRGVTVNAVAPGFIATDMTENLNAEP---ILQFIPLA-RYGQPEEVAGTIRFL 224 Query: 241 IENP---FLNGEVIRLDGAIRMQ 260 +P ++ G+ +DG + M Sbjct: 225 ATDPAAAYITGQTFNVDGGMVMF 247 >1GEE-A nrPDB Length = 261 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 20/266 (7%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCV 59 + ++G V VITG ++GLG + A R + A V+ + KK+G + Sbjct: 1 MYKDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAI 60 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 DVT E DV + A +FG++DV +N AG+ ++ + +L D+ +V+D Sbjct: 61 AVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEM------SLSDWNKVID 114 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 115 TNLTGAFLGSREAIKYFVENDI-----KGTVINMSSVHEKIPWPLFVHYAASKGGMKLMT 169 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTS--LPEKVCNFLASQVPFPSRLGDPAEYAHLV 237 +A + AP GIRV I PG TP+ + + S +P +G+P E A + Sbjct: 170 ETLALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPM-GYIGEPEEIAAVA 228 Query: 238 QAIIEN--PFLNGEVIRLDGAIRMQP 261 + + ++ G + DG + + P Sbjct: 229 AWLASSEASYVTGITLFADGGMTLYP 254 >3AUT-A nrPDB Length = 269 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 76/266 (28%), Positives = 120/266 (45%), Gaps = 20/266 (7%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSG----GEAQAKKLGNNCV 59 +K V VITGG++GLG A A R + A V+ N + + ++ G + Sbjct: 9 MYTDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAI 68 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 DVT E+DV + A +FG +DV +N AG+ ++ L +L+++ +V+D Sbjct: 69 IVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHEL------SLDNWNKVID 122 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 123 TNLTGAFLGSREAIKYFVENDI-----KGNVINMSSVHEMIPWPLFVHYAASKGGMKLMT 177 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEK--VCNFLASQVPFPSRLGDPAEYAHLV 237 +A + AP GIRV I PG TP+ + S +P +G P E A + Sbjct: 178 ETLALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPM-GYIGKPEEVAAVA 236 Query: 238 QAIIEN--PFLNGEVIRLDGAIRMQP 261 + + ++ G + DG + P Sbjct: 237 AFLASSQASYVTGITLFADGGMTKYP 262 >4NBV-A nrPDB Length = 246 Score = 239 bits (611), Expect = 7e-64, Method: Composition-based stats. Identities = 89/258 (34%), Positives = 131/258 (50%), Gaps = 18/258 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA--- 63 ++G VA+ITG A+G+G ATA+R GA VL D+ + A +L A Sbjct: 2 KLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRV 61 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DVT +V +A RVD+ VN AGI ++ + T F V+DVNL Sbjct: 62 DVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKM------TEAQFDAVIDVNLK 115 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G FN + VAG M + +GVI+N +SV G GQ Y+ASK G++G T A Sbjct: 116 GVFNCAQAVAGLMTEQ------GKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWA 169 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN 243 R+L P G+RV + PG T +L ++P+KV + + S + RL +PAE A + + + Sbjct: 170 RELGPKGVRVNAVCPGFVNTEILQTVPDKVLDGMTSSC-WLRRLAEPAEIASIYAFLASD 228 Query: 244 --PFLNGEVIRLDGAIRM 259 ++NG I G + + Sbjct: 229 DASYVNGVAIEASGGMSL 246 >2CDH-G nrPDB Length = 244 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 71/255 (27%), Positives = 115/255 (45%), Gaps = 20/255 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA----KKLGNNCVFAPADVTS 67 V V+TG + G+G A A L G ++ ++ + + G + DV+ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 E DV+ + A +G +DV VN AGI + +KK Q + V+D+NL G F Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQ------WDEVIDLNLTGVFL 116 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + M + ++G IIN ASV G +GQA Y+A+K G++G + AR+ A Sbjct: 117 CTQAATKIMMKK------RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGA 170 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII---ENP 244 I V + PG + + L E + + +P R G P A LV+ + Sbjct: 171 SRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPL-GRTGQPENVAGLVEFLALSPAAS 229 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ +DG I + Sbjct: 230 YITGQAFTIDGGIAI 244 >6NRP-A nrPDB Length = 263 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 64/253 (25%), Positives = 110/253 (43%), Gaps = 21/253 (8%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA----QAKKLGNNCVFAPADVT 66 ++TG + G+G A A +L G + + + LG N + DV Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + VQ L + G V AG+ L T +D+ V+ +L G + Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPAL------TDQDWDEVISTSLDGFY 138 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV++ + M + G I+ +SV+ G GQ YSA+K G++G T +A +L Sbjct: 139 NVLKPLIMPMIHLR-----KGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALEL 193 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--P 244 A I V +APGL T ++T ++V +P R+G E A +V+ + + Sbjct: 194 AKRKITVNCVAPGLIETEMVT---DEVKEHALKMIPL-QRMGQVDEVASVVKFLCSDEAS 249 Query: 245 FLNGEVIRLDGAI 257 ++ +VI ++G + Sbjct: 250 YVTRQVISVNGGL 262 >2NM0-A nrPDB Length = 253 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 110/257 (42%), Gaps = 23/257 (8%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADV 65 RS ++TGG G+GLA A G + E + D+ Sbjct: 17 RSHMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPE--------GFLAVKCDI 68 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T + V+ A + G V+V + AG+ + + EDF V++ NL GT Sbjct: 69 TDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSE------EDFTSVVETNLTGT 122 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F V++ M + ++G ++ +SV G GQA Y+ASK G+VG +AR+ Sbjct: 123 FRVVKRANRAMLR------AKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARE 176 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 L I +APG T + L ++ + SQVP R P E A V+ + + Sbjct: 177 LGSRNITFNVVAPGFVDTDMTKVLTDEQRANIVSQVPL-GRYARPEEIAATVRFLASDDA 235 Query: 244 PFLNGEVIRLDGAIRMQ 260 ++ G VI +DG + M Sbjct: 236 SYITGAVIPVDGGLGMG 252 >4IIN-A nrPDB Length = 271 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 66/263 (25%), Positives = 111/263 (42%), Gaps = 19/263 (7%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN----SGGEAQAKKLGNNC 58 + G +ITG + G+G A+ L G + N + + ++ G Sbjct: 22 SNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKA 81 Query: 59 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 D SE D A+ G + VN AG+ +K EDF V+ Sbjct: 82 AVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKT------EDFHHVI 135 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 D NL F R M ++ + G ++N AS+ G +GQ YSASKGG++ M Sbjct: 136 DNNLTSAFIGCREALKVMSKS------RFGSVVNVASIIGERGNMGQTNYSASKGGMIAM 189 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 + A + A IR ++ PG T + +L +++ +P +RLG E A V Sbjct: 190 SKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPL-NRLGSAKEVAEAVA 248 Query: 239 AIIEN--PFLNGEVIRLDGAIRM 259 ++ + ++ GE ++++G + M Sbjct: 249 FLLSDHSSYITGETLKVNGGLYM 271 >3OEC-A nrPDB Length = 317 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 46/287 (16%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------------PNSGGEA 49 A ++G VA ITG A G G A RL GA V +DL P E Sbjct: 39 ARMNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKET 98 Query: 50 --QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQ 107 ++ G + ADV +Q + A +FG +D+ V+ GI+ + +L Sbjct: 99 VRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSL---- 154 Query: 108 THTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA 167 T + + +L NL+G ++ R V M + GQ G +I +S G GQ+ Sbjct: 155 --TDQQWSDILQTNLIGAWHACRAVLPSMIER-----GQGGSVIFVSSTVGLRGAPGQSH 207 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSR- 226 Y+ASK G+ G+ L +A ++ IRV ++ PG T + +L EK+ + P+R Sbjct: 208 YAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVNTEM--ALNEKLLKMFLPHLENPTRE 265 Query: 227 ---------------LGDPAEYAHLVQAIIEN--PFLNGEVIRLDGA 256 +P + ++ V + + +++G I +DG Sbjct: 266 DAAELFSQLTLLPIPWVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >5VT6-A nrPDB Length = 269 Score = 233 bits (595), Expect = 6e-62, Method: Composition-based stats. Identities = 73/256 (28%), Positives = 114/256 (44%), Gaps = 20/256 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPN----SGGEAQAKKLGNNCVFAPADVT 66 VA +TGG GLG A + RL G + + S + G + DV Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVA 85 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + + FG+VDV +N AGI + + KG D+ V+ +L F Sbjct: 86 DFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKG------DWDAVMRTDLDAMF 139 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV + M + + G I+N SV G GQA Y+++K GI G T +A + Sbjct: 140 NVTKQFIAGMVER------RFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALET 193 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCN-FLASQVPFPSRLGDPAEYAHLVQAIIENP- 244 A GI V T++PG T ++ ++P+ V + Q+P RLG P E A L+ + + Sbjct: 194 AKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPV-GRLGRPDEVAALIAFLCSDDA 252 Query: 245 -FLNGEVIRLDGAIRM 259 F+ G + ++G + M Sbjct: 253 GFVTGADLAINGGMHM 268 >1GEG-A nrPDB Length = 256 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 73/262 (27%), Positives = 117/262 (44%), Gaps = 26/262 (9%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTS 67 VA++TG G+G A A RLV G + + D ++ +A A ++ G + V DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 V A+ A+ G DV VN AG+A ++ ++ T E +V ++N+ G Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPI------ESITPEIVDKVYNINVKGVIW 116 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ + G G IIN S A G A YS+SK + G+T ARDLA Sbjct: 117 GIQAAVEAFKKE-----GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLA 171 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLAS----------QVPFPSRLGDPAEYAHLV 237 P+GI V PG+ TP+ + +V + RL +P + A V Sbjct: 172 PLGITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACV 231 Query: 238 QAIIE--NPFLNGEVIRLDGAI 257 + + ++ G+ + +DG + Sbjct: 232 SYLASPDSDYMTGQSLLIDGGM 253 >3O4R-A nrPDB Length = 261 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 64/255 (25%), Positives = 107/255 (41%), Gaps = 17/255 (6%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPAD 64 + VA++T G+G A A RL GA V+ + L G + Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 V +D + +A A G +D+ V+ A + T E + + LD+N+ Sbjct: 73 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPF-----FGSIMDVTEEVWDKTLDINVKA 127 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + + V EM + G ++ +S+AAF G + Y+ SK ++G+T +A Sbjct: 128 PALMTKAVVPEMEKR------GGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 181 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLP-EKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE- 242 +LAP IRV +APGL T L +K + RLG+P + A +V + Sbjct: 182 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 241 Query: 243 -NPFLNGEVIRLDGA 256 ++ GE + + G Sbjct: 242 DASYITGETVVVGGG 256 >5OVL-A nrPDB Length = 300 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 108/252 (42%), Gaps = 23/252 (9%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ++TGG G+GLA A RL G + + + + DVT Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPD--------DLFGVQCDVTDSAA 120 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 V A + G V+V V AGI+ + + T E F+ V++ NL G F + Sbjct: 121 VDRAFKEVEEHQGPVEVLVANAGISKDAFLMRM------TEERFEEVINTNLTGAFRCAQ 174 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 + M + + G II SV+ G QA Y+A+K G++GM I+R+LA G Sbjct: 175 RASRTMQRK------RFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAG 228 Query: 191 IRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NPFLNG 248 + +APG T + +L E++ +P R+G E A V + ++ G Sbjct: 229 VTANVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAG 287 Query: 249 EVIRLDGAIRMQ 260 VI +DG + M Sbjct: 288 AVIPVDGGMGMG 299 >4RZI-B nrPDB Length = 240 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 77/254 (30%), Positives = 119/254 (46%), Gaps = 23/254 (9%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 ++ V V+TGG G+G A + L GA DL GG +A + A+VT Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA-------LGVVANVTD 58 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + + A A K G V V AGI + L T D+ VL+VNL G Sbjct: 59 LESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKL------TPADWDAVLNVNLKGVAY 112 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ M + + G I+ +S++ G VGQ YSA+K G++GM +AR+ A Sbjct: 113 SIKPFIEGMYER------KAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGA 166 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE---NP 244 G+R +APG T + ++ E + + ++PF R G P E A V ++ + Sbjct: 167 RYGVRANAVAPGFIDTEMTLAIREDIREKITKEIPF-RRFGKPEEIAWAVAFLLSPVASS 225 Query: 245 FLNGEVIRLDGAIR 258 ++ GEV+R++GA Sbjct: 226 YVTGEVLRVNGAHH 239 >1NFF-A nrPDB Length = 260 Score = 230 bits (586), Expect = 5e-61, Method: Composition-based stats. Identities = 81/252 (32%), Positives = 123/252 (48%), Gaps = 20/252 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G VA+++GGA G+G + +V +GA V D+ + G+A A +L + + DVT Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVT 63 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + A+ A FG + V VN AGI N+ + + L ++QR+LDVNL G F Sbjct: 64 QPAQWKAAVDTAVTAFGGLHVLVNNAGI------LNIGTIEDYALTEWQRILDVNLTGVF 117 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 IR V M + RG IIN +S+ G V Y+A+K + G+T A +L Sbjct: 118 LGIRAVVKPMKE------AGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALEL 171 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--P 244 P GIRV +I PGL TP+ +PE + R +P E ++LV + + Sbjct: 172 GPSGIRVNSIHPGLVKTPMTDWVPEDIFQTAL------GRAAEPVEVSNLVVYLASDESS 225 Query: 245 FLNGEVIRLDGA 256 + G +DG Sbjct: 226 YSTGAEFVVDGG 237 >5T5Q-A nrPDB Length = 247 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 80/256 (31%), Positives = 124/256 (48%), Gaps = 20/256 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN--NCVFAPADV 65 + V+TG G+G A AE GA+ VL DL G +A A LG+ AD Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 66 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 +S D + +ALA +FG +D V AGI A + D+ R + +NL G Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDA------DWHRTISINLDGV 120 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + + ++ I+ AS+AA+ G A Y A+KG +V MT ++R+ Sbjct: 121 FYLCKRALPALKEDS--------SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRE 172 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--N 243 LAP RV ++PG+ TP+ + L + + +Q P RLG P+E A ++ + Sbjct: 173 LAPK-TRVNGVSPGIIETPMTSELLKTRMDETMTQTPL-KRLGKPSEIASVIAFLCSPAA 230 Query: 244 PFLNGEVIRLDGAIRM 259 F+ GE I+++G I M Sbjct: 231 SFVTGETIQVNGGIYM 246 >1AE1-A nrPDB Length = 273 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 68/265 (25%), Positives = 120/265 (45%), Gaps = 27/265 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAPA 63 S+KG A++TGG+ G+G A E L G GA + ++ G N + Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVC 77 Query: 64 DVTSEKDVQTALALAKGKF-GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 D+ S + + F G++++ VN AG+ + K+ + T +D+ ++ N Sbjct: 78 DLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIH------KEAKDFTEKDYNIIMGTNF 131 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +++ ++ + + Q G +I +S+A F + YSASKG I MT + Sbjct: 132 EAAYHLSQIAYPLL------KASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSL 185 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLT-------SLPEKVCNFLASQVPFPSRLGDPAEYAH 235 A + A IRV ++APG+ TPL+ E++ NF+ + P R G P E + Sbjct: 186 ACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIV-KTPM-GRAGKPQEVSA 243 Query: 236 LVQAII--ENPFLNGEVIRLDGAIR 258 L+ + ++ G++I DG Sbjct: 244 LIAFLCFPAASYITGQIIWADGGFT 268 >2EW8-A nrPDB Length = 249 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 72/261 (27%), Positives = 109/261 (41%), Gaps = 22/261 (8%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-PNSGGEAQAKKLGNNCVFAP 62 + +K +AVITGGA+G+G A AER +GA + DL P EA + LG + Sbjct: 1 MTQRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVK 60 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV+ DV+ FGR D+ VN AGI L T E +++ ++N+ Sbjct: 61 CDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDEL------TFEQWKKTFEINV 114 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F + + M +N G IIN S + Y ++K +G T + Sbjct: 115 DSGFLMAKAFVPGMKRN------GWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRAL 168 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTS----LPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 A DL GI V IAP L T + V + +P RL P + Sbjct: 169 ASDLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP---RLQVPLDLTGAAA 225 Query: 239 AIIEN--PFLNGEVIRLDGAI 257 + + F+ G+ + +DG + Sbjct: 226 FLASDDASFITGQTLAVDGGM 246 >2ZAT-A nrPDB Length = 260 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 65/257 (25%), Positives = 109/257 (42%), Gaps = 17/257 (6%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAP 62 + ++ VA++T G+GLA A RL GA V+ + L G + Sbjct: 10 KPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTV 69 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 V +D + +A+A G VD+ V+ A + T E + ++L VN+ Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPF-----FGNIIDATEEVWDKILHVNV 124 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 T + + V EM + G ++ +SV A+ Y+ SK ++G+T + Sbjct: 125 KATVLMTKAVVPEMEKR------GGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNL 178 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLP-EKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 A +LAP IRV +APGL T L +K + RLG+P + A +V + Sbjct: 179 AVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLC 238 Query: 242 E--NPFLNGEVIRLDGA 256 ++ GE + + G Sbjct: 239 SEDASYITGETVVVGGG 255 >5OVJ-A nrPDB Length = 256 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 108/252 (42%), Gaps = 23/252 (9%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ++TGG G+GLA A RL G + + + + DVT Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPD--------DLFGVQCDVTDSAA 76 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 V A + G V+V V AGI+ + + T E F+ V++ NL G F + Sbjct: 77 VDRAFKEVEEHQGPVEVLVANAGISKDAFLMRM------TEERFEEVINTNLTGAFRCAQ 130 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 + M + + G II SV+ G QA Y+A+K G++GM I+R+LA G Sbjct: 131 RASRTMQRK------RFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAG 184 Query: 191 IRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NPFLNG 248 + +APG T + +L E++ +P R+G E A V + ++ G Sbjct: 185 VTANVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAG 243 Query: 249 EVIRLDGAIRMQ 260 VI +DG + M Sbjct: 244 AVIPVDGGMGMG 255 >2AE2-A nrPDB Length = 260 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 63/262 (24%), Positives = 119/262 (45%), Gaps = 24/262 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCVFAPA 63 +++G A++TGG+ G+G E L GAS Q + G + Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVC 65 Query: 64 DVTSEKDVQTALALAKGKF-GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 D++S + Q + F G++++ VN AGI + K+ + +T+ED+ ++ +N Sbjct: 66 DLSSRSERQELMNTVANHFHGKLNILVNNAGIVI------YKEAKDYTVEDYSLIMSINF 119 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +++ L + +E RG ++ +SV+ +A Y A+KG + +T + Sbjct: 120 EAAYHLSVLAHPFLKASE------RGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCL 173 Query: 183 ARDLAPIGIRVMTIAPGLFGT---PLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLV 237 A + A IRV + PG+ T + PE + N L + R+G+P E A +V Sbjct: 174 AFEWAKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCAL-RRMGEPKELAAMV 232 Query: 238 QAII--ENPFLNGEVIRLDGAI 257 + ++ G++I +DG + Sbjct: 233 AFLCFPAASYVTGQIIYVDGGL 254 >4IIV-A nrPDB Length = 267 Score = 223 bits (569), Expect = 5e-59, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 110/253 (43%), Gaps = 19/253 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASA-VLLDLPNSGGEAQAKKL---GNNCVFAPADVT 66 ++TG + G+G A A +L G + V +G + + G N DV Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVA 86 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + + + L + G V+ AGIA + L + +D+ V+ NL + Sbjct: 87 NREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPAL------SNDDWDAVIHTNLDSFY 140 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NVI+ M Q G II +SV+ G GQ YSA+K GI+G T +A +L Sbjct: 141 NVIQPCIMPMIGAR-----QGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIEL 195 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--P 244 A I V IAPGL T ++ + E S +P R+G E A L ++ + Sbjct: 196 AKRKITVNCIAPGLIDTGMIE-MEESALKEAMSMIPM-KRMGQAEEVAGLASYLMSDIAG 253 Query: 245 FLNGEVIRLDGAI 257 ++ +VI ++G + Sbjct: 254 YVTRQVISINGGM 266 >5OJG-A nrPDB Length = 260 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 74/268 (27%), Positives = 122/268 (45%), Gaps = 21/268 (7%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 M + CR +G VA++T G+GLA AERL+ +GAS V+ + + L N + Sbjct: 1 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLT 60 Query: 61 APA----DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQR 116 A + S D + + KFG++++ VN GI A + + + + Sbjct: 61 KVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPA-----FGHILEVSDQVWDK 115 Query: 117 VLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 + +VN+ F + +LV + + G II AS +A++ G AAY +K +V Sbjct: 116 LFEVNVKAGFQMTKLVHPHIAKE------GGGAIIFNASYSAYKSPPGIAAYGVTKTTLV 169 Query: 177 GMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLP----EKVCNFLASQVPFPSRLGDPAE 232 G+T +A LA IRV IAPG+ T + L + Q RLG P + Sbjct: 170 GLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDD 229 Query: 233 YAHLVQAIIEN--PFLNGEVIRLDGAIR 258 A V + + ++ GE+I + G ++ Sbjct: 230 CAGTVAYLASDDSSYITGEMIIIAGGVQ 257 >1UZM-A nrPDB Length = 247 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 71/252 (28%), Positives = 115/252 (45%), Gaps = 23/252 (9%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ++TGG G+GLA A+RL G + + + DVT Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL--------FGVEVDVTDSDA 67 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 V A + G V+V V+ AG++ + + T E F++V++ NL G F V + Sbjct: 68 VDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRM------TEEKFEKVINANLTGAFRVAQ 121 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 + M +N + G +I SV+ G QA Y+ASK G++GM IAR+L+ Sbjct: 122 RASRSMQRN------KFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKAN 175 Query: 191 IRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NPFLNG 248 + +APG T + +L E++ +P R+G PAE A +V + +++G Sbjct: 176 VTANVVAPGYIDTDMTRALDERIQQGALQFIP-AKRVGTPAEVAGVVSFLASEDASYISG 234 Query: 249 EVIRLDGAIRMQ 260 VI +DG + M Sbjct: 235 AVIPVDGGMGMG 246 >3WTC-A nrPDB Length = 262 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 68/266 (25%), Positives = 122/266 (45%), Gaps = 26/266 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK---LGNNCVFAPA 63 S+ G +A +TG A G+G A A RL GA +LLD+ AK+ LG V A Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTA 64 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 D+++ ++ LA A G +D+ VN AGI +++ + +++ +N+ Sbjct: 65 DISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEI------EKIFSINVQ 118 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G ++ A + G +G IIN S+A EG AYSA+K + +T A Sbjct: 119 GVLWGMQAAATLFKEK-----GTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAA 173 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQV----------PFPSRLGDPAEY 233 ++LA GI V + PG+ GT + ++ +++ +++ R+ + Sbjct: 174 KELASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDV 233 Query: 234 AHLVQAIIEN--PFLNGEVIRLDGAI 257 A V + + ++ G+ + +DG + Sbjct: 234 AGFVAYLSSSDADYMTGQSVLIDGGL 259 >4Z9Y-A nrPDB Length = 253 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 70/262 (26%), Positives = 119/262 (45%), Gaps = 17/262 (6%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKLGNNCV 59 M ++G VA+ITG +GLG A L G V +++ + LG + Sbjct: 1 MILNSFDLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFL 60 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 AD+++ + A +FG VD+ VN AGI + +++ V++ Sbjct: 61 SLTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSE------KNWDDVMN 114 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 +N+ F + + VA + + G+ G IIN AS+ +F+G + +Y+ASK ++G+T Sbjct: 115 LNIKSVFFMSQTVARQFIKQ-----GKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVT 169 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAH-- 235 +A + A GI V IAPG T L E+ + ++P R G P + Sbjct: 170 RLMANEWAKHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIP-AGRWGLPQDLMGPS 228 Query: 236 LVQAIIENPFLNGEVIRLDGAI 257 + A + ++NG I +DG Sbjct: 229 VFLASSASDYINGYTIAVDGGW 250 >5U9P-A nrPDB Length = 265 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 115/259 (44%), Gaps = 20/259 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPA 63 + G A+ITG G+GL A L GA+ V+ D A++ G A Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF 76 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV V+ A+ + + G +D+ VN AGI + + +D+ ++ VNL Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEP------DDWHALMRVNLD 130 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G FNV + VA M G IIN SV + + A Y+A+KG + +T + Sbjct: 131 GVFNVAQAVARHMIAR------GHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMC 184 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKV--CNFLASQVPFPSRLGDPAEY--AHLVQA 239 D A GI+ +APG F T L +L + ++L + P R G E A + A Sbjct: 185 ADWARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTP-AGRWGQVDELCGAAIFLA 243 Query: 240 IIENPFLNGEVIRLDGAIR 258 + F+NG+ + +DG + Sbjct: 244 SAASDFVNGQTLFVDGGLT 262 >3RWB-A nrPDB Length = 247 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 113/255 (44%), Gaps = 13/255 (5%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + G A++TG A G+G A A RL GA+ ++ D+ G +A A +G AD Sbjct: 1 TERLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAAD 60 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 ++ V+ A + G +D+ VN A I L+ +++++DVNL G Sbjct: 61 ISDPGSVKALFAEIQALTGGIDILVNNASIVP------FVAWDDVDLDHWRKIIDVNLTG 114 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 TF V R +M G+ G +I+ AS F G AAY A+KGG++G T +A Sbjct: 115 TFIVTRAGTDQMRA-----AGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALAT 169 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 244 +L I + PGL + + + P + G P A +V + + Sbjct: 170 ELGKYNITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDD 229 Query: 245 --FLNGEVIRLDGAI 257 ++ G+ + +D + Sbjct: 230 ARWITGQTLNVDAGM 244 >3PPI-A nrPDB Length = 281 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 107/257 (41%), Positives = 154/257 (59%), Gaps = 1/257 (0%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + +G A+++GGA GLG AT RL G V+ DL G+A A +LGN F + Sbjct: 25 IKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTN 84 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 VTSE V A+ A + GR+ AV G ++ + G + F + +D+ L G Sbjct: 85 VTSEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNG 143 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T+NV RLVA + EP + G+RG ++ TAS+A +EGQ+GQ AY+A+K G++G+T+ AR Sbjct: 144 TYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAAR 203 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 244 DL+ GIRV TIAPG TP++ S+ E+ A+ +PFP RLG P E+A ++ N Sbjct: 204 DLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFADAAAFLLTNG 263 Query: 245 FLNGEVIRLDGAIRMQP 261 ++NGEV+RLDGA R P Sbjct: 264 YINGEVMRLDGAQRFTP 280 >6CI9-A nrPDB Length = 259 Score = 218 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 63/259 (24%), Positives = 109/259 (42%), Gaps = 19/259 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN---NCVFAPA 63 S++G A++TGG+ G+G AE G V+ + L A Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRA 65 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DVT +D + +A + G +D+ AGI + + +L T +D ++VL VN Sbjct: 66 DVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDL------TPDDIEQVLGVNFK 119 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPI 182 GT +++ + G ++ T+S+ G G + Y ASK +G Sbjct: 120 GTVYIVQAALQALT------ASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTA 173 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII- 241 A +LAP I + + PG T L + + + +AS +P RLG A+ + Sbjct: 174 AMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIP-AGRLGSVADIGNAALFFAT 232 Query: 242 -ENPFLNGEVIRLDGAIRM 259 E ++ G+ + +DG + Sbjct: 233 DEAAYVTGQTLVVDGGQVL 251 >3WYE-A nrPDB Length = 256 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 76/262 (29%), Positives = 119/262 (45%), Gaps = 26/262 (9%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTS 67 VA++TG G+G A A RLV G + + D ++ +A A ++ G + V DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 V A+ A+ G DV VN AGIA +K T ED +++ VN+ F Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGIA------QIKPLLEVTEEDLKQIYSVNVFSVFF 116 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ + G G IIN AS+AA +G +AYS +K + G+T ARDLA Sbjct: 117 GIQAAVEAFKKE-----GHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLA 171 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQV----------PFPSRLGDPAEYAHLV 237 P+GI V PG+ GT + + ++ + R P + A LV Sbjct: 172 PLGITVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLV 231 Query: 238 QAIIE--NPFLNGEVIRLDGAI 257 + + ++ G+ + +DG + Sbjct: 232 SFLASPDSDYMTGQSLLIDGGM 253 >2Q2Q-A nrPDB Length = 255 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 75/265 (28%), Positives = 114/265 (43%), Gaps = 27/265 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSG-GEAQAKKLGNNCVFAPADV 65 ++KG A++TG SG+GL A+ L GA+ VL + A+ + G V PAD+ Sbjct: 1 TLKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADL 60 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + ++ ALA+ +FG VD+ VN AGI + LE + +++ +NL Sbjct: 61 SDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFP------LESWDKIIALNLSAV 114 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F+ RL M G IIN ASV G G+AAY A+K G+VG+T + + Sbjct: 115 FHGTRLALPGMRARN------WGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLE 168 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEK-----------VCNFLASQVPFPSRLGDPAEYA 234 A + I PG TPL+ + + LA + P + P Sbjct: 169 TATSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLA-FVTPEHLG 227 Query: 235 HLVQAIIE--NPFLNGEVIRLDGAI 257 LV + + G +DG Sbjct: 228 ELVLFLCSEAGSQVRGAAWNVDGGW 252 >1YXM-A nrPDB Length = 303 Score = 215 bits (548), Expect = 1e-56, Method: Composition-based stats. Identities = 59/267 (22%), Positives = 117/267 (43%), Gaps = 28/267 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN--------CV 59 ++G VA++TGGA+G+G A + L+ G++ V+ ++ A +L N + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 ++ +E++V + FG+++ VN G L + + + + VL+ Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQF------LSPAEHISSKGWHAVLE 129 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL GTF + + V + G I+N V G A++ G+ +T Sbjct: 130 TNLTGTFYMCKAVYSSWMKEH------GGSIVNII-VPTKAGFPLAVHSGAARAGVYNLT 182 Query: 180 LPIARDLAPIGIRVMTIAPGLFGT-PLLTSLPEKVCNFLA---SQVPFPSRLGDPAEYAH 235 +A + A GIR+ +APG+ + + + +F ++P R+G P E + Sbjct: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEVSS 241 Query: 236 LVQAIIE--NPFLNGEVIRLDGAIRMQ 260 +V ++ F+ G+ + +DG + Sbjct: 242 VVCFLLSPAASFITGQSVDVDGGRSLY 268 >4IS3-A nrPDB Length = 268 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 68/261 (26%), Positives = 118/261 (45%), Gaps = 20/261 (7%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN-----NCV 59 V+ V +ITGG G+G A A+ + GA + + +L + Sbjct: 20 MNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVL 79 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 D+TS V A+ K+GR+DV +N AGI + + + E+F+ ++D Sbjct: 80 GFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSE------EEFKHIMD 133 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 +N+ G FN + + ++GVIINTASV G + Y ASK ++G+T Sbjct: 134 INVTGVFNGA------WCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLT 187 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 + R++ IRV+ +APG+ T + P ++ +P R+ +P E A++ Sbjct: 188 HGLGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPM-KRMLEPEEIANVYLF 246 Query: 240 IIEN--PFLNGEVIRLDGAIR 258 + + + + +DGA R Sbjct: 247 LASDLASGITATTVSVDGAYR 267 >3UVE-A nrPDB Length = 286 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 67/293 (22%), Positives = 115/293 (39%), Gaps = 45/293 (15%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------------PNSGGEA 49 + V+G VA +TG A G G + A RL +GA + +D+ P S E Sbjct: 4 SMTGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPED 63 Query: 50 QAKKL------GNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNL 103 A+ V A DV ++ A+ + GR+D+ V AGI T + Sbjct: 64 LAETADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLD- 122 Query: 104 KKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163 + ED+ ++D+NL G + ++ M GG+ G II T+SV + Sbjct: 123 ----KTSEEDWTEMIDINLAGVWKTVKAGVPHMIA-----GGRGGSIILTSSVGGLKAYP 173 Query: 164 GQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL-------------- 209 Y A+K G+VG+ +L IRV ++ P TP+L + Sbjct: 174 HTGHYVAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPG 233 Query: 210 PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDGAIRMQ 260 P+ + P +P + ++ V + ++ G + +D ++ Sbjct: 234 PDDMAPICQMFHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCLK 286 >2HSD-A nrPDB Length = 253 Score = 212 bits (541), Expect = 9e-56, Method: Composition-based stats. Identities = 80/258 (31%), Positives = 127/258 (49%), Gaps = 15/258 (5%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADV 65 + G +ITGGA GLG A + V GA VL D+ + G A A++LG+ + DV Sbjct: 1 NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDV 60 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T E+D Q +A A+ +FG VD VN AGI+ +T ++E F++V+++NL G Sbjct: 61 TIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFL------ETESVERFRKVVEINLTGV 114 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F ++ V M + G I+N +S A G ++Y ASK G+ G++ A + Sbjct: 115 FIGMKTVIPAM------KDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVE 168 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 L IRV ++ PG+ TP+ + P R+G+P E A V ++ + Sbjct: 169 LGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPM-GRVGEPGEIAGAVVKLLSDTS 227 Query: 244 PFLNGEVIRLDGAIRMQP 261 ++ G + +DG P Sbjct: 228 SYVTGAELAVDGGWTTGP 245 >2CFC-A nrPDB Length = 250 Score = 212 bits (541), Expect = 9e-56, Method: Composition-based stats. Identities = 82/256 (32%), Positives = 126/256 (49%), Gaps = 18/256 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAK----KLGNNCVFAPADVT 66 VA++TG +SG GLA A R + +G LDL E A+ + + ADV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E DV A+A +FG +DV VN AGI S+ L T +E F +V+ VN+ G F Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVL---HTTPVEQFDKVMAVNVRGIF 119 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R V M GVI+N ASVA+ G++AY+ SKG ++ +T +A D Sbjct: 120 LGCRAVLPHMLLQ------GAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDY 173 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAII--E 242 A GIR + PG+ TP+ + ++ + + +++P +G A+ A V + + Sbjct: 174 AGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIP-QKEIGTAAQVADAVMFLAGED 232 Query: 243 NPFLNGEVIRLDGAIR 258 ++NG + +DGA Sbjct: 233 ATYVNGAALVMDGAYT 248 >3T7C-A nrPDB Length = 299 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 67/289 (23%), Positives = 118/289 (40%), Gaps = 41/289 (14%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------------PNSGGEA 49 + V+G VA ITG A G G + A L +GA + +D+ P+ E Sbjct: 21 SMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAET 80 Query: 50 --QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQ 107 Q + LG + + DV +Q A+ + GR+D+ + A +A N + Sbjct: 81 VRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPK 140 Query: 108 THTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA 167 T ++ ++DVNL G + R+ + G + G I+ T+S+ G Sbjct: 141 T-----WRDMIDVNLNGAWITARVAIPHIMA-----GKRGGSIVFTSSIGGLRGAENIGN 190 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLP--------------EKV 213 Y ASK G+ G+ +A +L P IRV + P TP+L + P E Sbjct: 191 YIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDF 250 Query: 214 CNFLASQVPFPSRLGDPAEYAHLVQAIIENP--FLNGEVIRLDGAIRMQ 260 P +PA+ ++ + ++ + ++ G + +DG ++ Sbjct: 251 QVASRQMHVLPIPYVEPADISNAILFLVSDDARYITGVSLPVDGGALLK 299 >3W8F-A nrPDB Length = 260 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 65/269 (24%), Positives = 100/269 (37%), Gaps = 30/269 (11%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLP-----NSGGEAQAKKLGNNCVFAP 62 +KG AV+TG SG+GLA A L GA V+ K G + Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 AD++ + + +A A G +D+ VN AGI + ++ + ++ +NL Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFP------VDKWNAIIALNL 115 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F+ M + G IIN AS V ++AY A+K G+VG+T Sbjct: 116 SAVFHGTAAALPIMQKQ------GWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVT 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSR-----------LGDPA 231 A + A GI I PG TPL+ E + + +R P Sbjct: 170 ALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPE 229 Query: 232 EYAHLVQAI--IENPFLNGEVIRLDGAIR 258 + + + G + LDG Sbjct: 230 QLGGAAVFLSSAAADQMTGTTLSLDGGWT 258 >1K2W-A nrPDB Length = 256 Score = 210 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 69/266 (25%), Positives = 114/266 (42%), Gaps = 25/266 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G A+ITG A G+G A AE V +GA + D+ A A ++G DVT Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVT 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + + +A ++G +D+ VN A ++L T E + R+ +N+ GT Sbjct: 62 DQASIDRCVAELLDRWGSIDILVNNA------ALFDLAPIVEITRESYDRLFAINVSGTL 115 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 +++ VA M GG+ G IIN AS A G+ Y A+K ++ +T +L Sbjct: 116 FMMQAVARAMIA-----GGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNL 170 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNF-----------LASQVPFPSRLGDPAEYAH 235 GI V IAPG+ + K ++ + + VPF R+G + Sbjct: 171 IRHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPF-GRMGRAEDLTG 229 Query: 236 LVQAII--ENPFLNGEVIRLDGAIRM 259 + + E ++ + +DG M Sbjct: 230 MAIFLATPEADYIVAQTYNVDGGNWM 255 >3V2G-A nrPDB Length = 271 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 112/257 (43%), Gaps = 23/257 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA----QAKKLGNNCVFAP 62 S+ G A +TGG+ G+G A A+RL +GA+ L + + + ++ G V Sbjct: 28 SLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIR 87 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 AD + ++ A+ G +D+ VN AGI ++ + T+ DF V+ VN Sbjct: 88 ADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPL------EETTVADFDEVMAVNF 141 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTAS-VAAFEGQVGQAAYSASKGGIVGMTLP 181 F IR + + G G II S +A G + YSASK + G+T Sbjct: 142 RAPFVAIRSASRHL--------GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKG 193 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 +ARDL P GI V + PG T + + + + G+P + A LV + Sbjct: 194 LARDLGPRGITVNIVHPGSTDTDMNPADGDHAEAQ--RERIATGSYGEPQDIAGLVAWLA 251 Query: 242 --ENPFLNGEVIRLDGA 256 + F+ G + +DG Sbjct: 252 GPQGKFVTGASLTIDGG 268 >1DOH-A nrPDB Length = 283 Score = 210 bits (534), Expect = 7e-55, Method: Composition-based stats. Identities = 68/272 (25%), Positives = 111/272 (40%), Gaps = 33/272 (12%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLP----NSGGEAQAKKLGNNCVFAP 62 S++G VA++TG G+G A L +G ++ A KK G++ Sbjct: 26 SLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVK 85 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 A+V +D+ A FG++D+ + +G+ ++ T E+F RV +N Sbjct: 86 ANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDV------TPEEFDRVFTINT 139 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAF-EGQVGQAAYSASKGGIVGMTLP 181 G F V R + G +I S+ + A YS SKG I Sbjct: 140 RGQFFVAREAYKHLEI--------GGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARC 191 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSL------------PEKVCNFLASQVPFPSRLGD 229 +A D+A I V +APG T + ++ E+V + A Q R+G Sbjct: 192 MAIDMADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGL 251 Query: 230 PAEYAHLVQAIIENP--FLNGEVIRLDGAIRM 259 P + A +V + N ++ G+VI +DG M Sbjct: 252 PIDIARVVCFLASNDGGWVTGKVIGIDGGACM 283 >1HXH-A nrPDB Length = 253 Score = 208 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 121/258 (46%), Gaps = 21/258 (8%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 ++G VA++TGGASG+GL + L+G+GA D+ + G+ A +LG +F D Sbjct: 1 TNRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHD 60 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 V+SE D +A + + G ++V VN AGI + +T LEDF R+L +N Sbjct: 61 VSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPG------DMETGRLEDFSRLLKINTES 114 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + M + G IIN ASV+++ A YSASK + +T A Sbjct: 115 VFIGCQQGIAAMKET-------GGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAAL 167 Query: 185 DLAPIG--IRVMTIAPGLFGTPLLTS-LPEKVCNFLASQVPFPSRLGD---PAEYAHLVQ 238 G IRV +I P TP++ + LP+ V + P +R G P A LV Sbjct: 168 SCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVL 227 Query: 239 AIIEN--PFLNGEVIRLD 254 + + ++G + D Sbjct: 228 FLASDESSVMSGSELHAD 245 >2X9N-A nrPDB Length = 288 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 59/262 (22%), Positives = 102/262 (38%), Gaps = 17/262 (6%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPN-----SGGEAQAKKLGNNCVFAPADVTS 67 AV+TG A +G A A +L G V+ + S + K+ N V AD+T+ Sbjct: 26 AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTN 85 Query: 68 ----EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTY----NLKKGQTHTLEDFQRVLD 119 + + FGR DV VN A + ++ Sbjct: 86 SNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG 145 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 N + F + A P+ I+N + + + Y+ K +VG+T Sbjct: 146 TNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLT 205 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 A +LAP GIRV +APG+ P+ ++ E+ + +VP R + A V Sbjct: 206 QSAALELAPYGIRVNGVAPGVSLLPV--AMGEEEKDKWRRKVPLGRREASAEQIADAVIF 263 Query: 240 IIENP--FLNGEVIRLDGAIRM 259 ++ ++ G +I++DG + + Sbjct: 264 LVSGSAQYITGSIIKVDGGLSL 285 >3V2H-A nrPDB Length = 281 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 74/273 (27%), Positives = 120/273 (43%), Gaps = 30/273 (10%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGNNCVF 60 +S+ AVITG SG+GLA A L GA+ VL D + + A + Sbjct: 21 QSMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLH 80 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 PAD+T ++ +A+ +FG D+ VN AG+ ++K + +E + R++ V Sbjct: 81 HPADMTKPSEIADMMAMVADRFGGADILVNNAGVQF------VEKIEDFPVEQWDRIIAV 134 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL +F+ IR M + G IIN AS ++AY A+K GI+G+T Sbjct: 135 NLSSSFHTIRGAIPPMKKK------GWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTK 188 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTS-----------LPEKVCNFLASQVPFPSRLGD 229 +A ++A G+ V +I PG TPL+ E+V N + + + Sbjct: 189 TVALEVAESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFIT 248 Query: 230 PAEYAHLVQAII--ENPFLNGEVIRLDGAIRMQ 260 + A L + + + G + +DG Q Sbjct: 249 VEQVASLALYLAGDDAAQITGTHVSMDGGWTAQ 281 >3R3S-A nrPDB Length = 294 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 66/263 (25%), Positives = 112/263 (42%), Gaps = 23/263 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQ-----AKKLGNNCVFA 61 +K A++TGG SG+G A A +GA + LP +AQ ++ G V Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 P D++ E ++ + A+ G +D+ AG K + + + T E FQ+ VN Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAG-----KQTAIPEIKDLTSEQFQQTFAVN 160 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + F + + + + II T+S+ A++ Y+A+K I+ + Sbjct: 161 VFALFWITQEAIPLLPK--------GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRG 212 Query: 182 IARDLAPIGIRVMTIAPGLFGTPL--LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 +A+ +A GIRV +APG T L + Q P R G PAE A + Sbjct: 213 LAKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPM-KRAGQPAELAPVYVY 271 Query: 240 II--ENPFLNGEVIRLDGAIRMQ 260 + E+ ++ EV + G + Sbjct: 272 LASQESSYVTAEVHGVCGGEHLG 294 >4E6P-A nrPDB Length = 259 Score = 207 bits (528), Expect = 4e-54, Method: Composition-based stats. Identities = 66/270 (24%), Positives = 113/270 (41%), Gaps = 25/270 (9%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAP 62 + + ++G A+ITG A G+G A AE V +GA+ + D+ A ++G Sbjct: 1 SMMKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQ 60 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DVT + + A+A G +D+ VN A ++L T E ++++ +N+ Sbjct: 61 MDVTRQDSIDAAIAATVEHAGGLDILVNNA------ALFDLAPIVEITRESYEKLFAINV 114 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 GT ++ A +M G+ G IIN AS A G+ A Y A+K ++ +T Sbjct: 115 AGTLFTLQAAARQMIAQ-----GRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSA 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE-----------KVCNFLASQVPFPSRLGDPA 231 DL I V IAPG+ + + + VPF R+G Sbjct: 170 GLDLIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPF-GRMGTAE 228 Query: 232 EYAHLVQAI--IENPFLNGEVIRLDGAIRM 259 + + + E+ ++ + +DG M Sbjct: 229 DLTGMAIFLASAESDYIVSQTYNVDGGNWM 258 >5YSS-A nrPDB Length = 256 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 66/267 (24%), Positives = 114/267 (42%), Gaps = 25/267 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKLGNNCVFAPADV 65 ++ G A++TG SG+GL A+ L GA+ +L + + + G + AD+ Sbjct: 2 NLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADL 61 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + E + + A+ +FG VD+ +N AGI ++ +T ++ + ++ +NL Sbjct: 62 SDEAQIADMMRYAESEFGGVDILINNAGIQ------HVSPIETFPVDKWNAIIAINLSSV 115 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F+ RL M G IIN ASV ++AY A+K G+VG+T IA + Sbjct: 116 FHTTRLALPGMRARN------WGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALE 169 Query: 186 LAPIGIRVMTIAPGLFGTPLLT----------SLPEKVCNFLASQVPFPSRLGDPAEYAH 235 A I + PG TPL+ + PE + L ++ P + + Sbjct: 170 TAQTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGN 229 Query: 236 LVQAIIENPF--LNGEVIRLDGAIRMQ 260 L + + + G +DG Q Sbjct: 230 LALFLCSDGAAQVRGVAWNMDGGWVAQ 256 >4DBZ-A nrPDB Length = 281 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 75/262 (28%), Positives = 113/262 (43%), Gaps = 27/262 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 VA++TG SG+GL A RL +G + G K+L G DV S Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRSV 87 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 +++ +A ++G VDV VN AG T L E + V++ NL G F V Sbjct: 88 PEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELAD------ELWLDVVETNLTGVFRV 141 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + V + G I+N AS +G V A YSASK G+VG T + +LA Sbjct: 142 TKQVL----KAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELAR 197 Query: 189 IGIRVMTIAPGLFGTPLLTSLP-----------EKVCNFLASQVPFPSRLGDPAEYAHLV 237 GI V + PG TP+ S+ E+ + + ++VP R P+E A +V Sbjct: 198 TGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPI-GRYVQPSEVAEMV 256 Query: 238 QAII--ENPFLNGEVIRLDGAI 257 +I + + + + G + Sbjct: 257 AYLIGPGAAAVTAQALNVCGGL 278 >2QHX-A nrPDB Length = 328 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 67/282 (23%), Positives = 112/282 (39%), Gaps = 36/282 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA------KKLGNNCVFAPADV 65 VA++TG A LG + AE L +G AV L S EA A + N+ + AD+ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGY-AVCLHYHRSAAEANALSATLNARRPNSAITVQADL 106 Query: 66 TSEKD-----------------VQTALALAKGKFGRVDVAVNCAGIAVASKTYN-LKKGQ 107 ++ +A +GR DV VN A + + G Sbjct: 107 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 166 Query: 108 THTLEDFQ-------RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE 160 + D + + N + + +I+ A + G IIN + Sbjct: 167 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 226 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQ 220 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+ Sbjct: 227 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSK 284 Query: 221 VPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDGAIRMQ 260 VP R AE + +V + + ++ G +++DG + Sbjct: 285 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 326 >2BFA-A nrPDB Length = 288 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 67/282 (23%), Positives = 112/282 (39%), Gaps = 36/282 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA------KKLGNNCVFAPADV 65 VA++TG A LG + AE L +G AV L S EA A + N+ + AD+ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGY-AVCLHYHRSAAEANALSATLNARRPNSAITVQADL 66 Query: 66 TSEKD-----------------VQTALALAKGKFGRVDVAVNCAGIAVASKTYN-LKKGQ 107 ++ +A +GR DV VN A + + G Sbjct: 67 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 126 Query: 108 THTLEDFQ-------RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE 160 + D + + N + + +I+ A + G IIN + Sbjct: 127 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 186 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQ 220 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+ Sbjct: 187 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSK 244 Query: 221 VPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDGAIRMQ 260 VP R AE + +V + + ++ G +++DG + Sbjct: 245 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 286 >3A28-C nrPDB Length = 258 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 77/264 (29%), Positives = 122/264 (46%), Gaps = 28/264 (10%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFAPADV 65 VA++TGGA G+G +E+L G + DLP +A + VF DV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 T + + +A+ A K G DV VN AGIA +K T ED +++ VN+ Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIA------QIKPLLEVTEEDLKQIYSVNVFSV 116 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F I+ + + D+ G +G IIN AS+AA +G +AYS +K + G+T A++ Sbjct: 117 FFGIQAASRKF-----DELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQE 171 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQV----------PFPSRLGDPAEYAH 235 LAP G V APG+ GT + + ++ + R P + A Sbjct: 172 LAPKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAG 231 Query: 236 LVQAIIE--NPFLNGEVIRLDGAI 257 LV + + ++ G+V+ +DG + Sbjct: 232 LVSFLASENSNYVTGQVMLVDGGM 255 >4HP8-A nrPDB Length = 247 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 110/257 (42%), Gaps = 24/257 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL--PNSGGEAQAKKLGNNCVFAPAD 64 S++G A++TG +GLG A A L GA V P+ + AK G N D Sbjct: 6 SLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKD-GGNASALLID 64 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 + + A D+ VN AGI + + + D+ V+DVNL Sbjct: 65 FADPLAAKDSFTDA-----GFDILVNNAGIIRRADSVEFSEL------DWDEVMDVNLKA 113 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + A E+ G+ G ++N AS+ +F+G + +Y+A+K G+ G+T +A Sbjct: 114 LFFTTQAFAKELLAK-----GRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLAN 168 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLPEKVC--NFLASQVPFPSRLGDPAEYAHLVQAI-- 240 + A GI V IAPG T +L + ++P R G + A + Sbjct: 169 EWAAKGINVNAIAPGYIETNNTEALRADAARNKAILERIP-AGRWGHSEDIAGAAVFLSS 227 Query: 241 IENPFLNGEVIRLDGAI 257 +++G ++ +DG Sbjct: 228 AAADYVHGAILNVDGGW 244 >5EJ2-A nrPDB Length = 308 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 63/286 (22%), Positives = 112/286 (39%), Gaps = 41/286 (14%) Query: 2 AAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL-------------PNSGGE 48 A V G VA I+G A G G + A RL +GA + +D+ P E Sbjct: 29 AVMTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAE 88 Query: 49 A--QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKG 106 K L V A DV + +++A+ + GR+D+ V AG+ +K Sbjct: 89 TADLVKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDG-----RKL 143 Query: 107 QTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA 166 +Q ++D+NL G ++ ++ + GG+ G I+ T+SV + Sbjct: 144 HKIRDNVWQDMIDINLTGVWHTVKAGVPHVL-----SGGRGGSIVLTSSVGGRKAYPNTG 198 Query: 167 AYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--------------PEK 212 Y A+K G++G+ A +L P IRV + P T ++ + P+ Sbjct: 199 HYIAAKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDD 258 Query: 213 VCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDGA 256 P D ++ ++ V + + ++ G + +D Sbjct: 259 FAPISQMMHTLPVPWVDASDISNAVLFLASDESRYVTGVSLPVDAG 304 >4MOW-A nrPDB Length = 256 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 68/262 (25%), Positives = 113/262 (43%), Gaps = 24/262 (9%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCVF 60 + G VA++TG + G+G A A+ L +GA+ V+ + G + + G V Sbjct: 9 MSKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVA 68 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 DV+ D Q + A +GR+DV VN +G+ Y + T E ++R D Sbjct: 69 VGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGV------YEFAPIEAITEEHYRRQFDT 122 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 N+ G + + G+ IIN +SV A YS +KG + +T Sbjct: 123 NVFGVLLTTQAAVKHL--------GEGASIINISSVVTSITPPASAVYSGTKGAVDAITG 174 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTS---LPEKVCNFLASQVPFPSRLGDPAEYAHLV 237 +A +L P IRV I PG+ T S + + + Q P RLG+P + A + Sbjct: 175 VLALELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPL-GRLGEPNDIASVA 233 Query: 238 QAIIENP--FLNGEVIRLDGAI 257 + + ++ GE + + G + Sbjct: 234 VFLASDDARWMTGEHLVVSGGL 255 >1X1T-A nrPDB Length = 260 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 68/269 (25%), Positives = 106/269 (39%), Gaps = 30/269 (11%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFAP 62 +KG VAV+TG SG+GL A L QGA VL ++ A + G ++ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 AD++ + V+ + A + GR+D+ VN AGI + + E + +L +NL Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPT------EKWDAILALNL 115 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F+ M + G IIN AS ++AY A+K G+VG T Sbjct: 116 SAVFHGTAAALPHMKKQ------GFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVT 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCN-----------FLASQVPFPSRLGDPA 231 A + A GI I PG TPL+ + L S+ + P Sbjct: 170 ALETAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPE 229 Query: 232 EYAHLVQAIIENPF--LNGEVIRLDGAIR 258 + + + + G + +DG Sbjct: 230 QLGGTAVFLASDAAAQITGTTVSVDGGWT 258 >3U5T-A nrPDB Length = 267 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 114/254 (44%), Gaps = 22/254 (8%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA----KKLGNNCVFAPADVT 66 VA++TG + G+G A A RL G + V+ + + + G + A ADV+ Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQADVS 87 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 V+ A A+ FG VDV VN AGI + F RV+ VNL GTF Sbjct: 88 DPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAV------FDRVIAVNLKGTF 141 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N +R A + G IIN ++ Y+A+K G+ MT ++++L Sbjct: 142 NTLREAAQRLRV--------GGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKEL 193 Query: 187 APIGIRVMTIAPGLFGTPL-LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--EN 243 I V +APG T L L ++V + A P RLG P + A V + + Sbjct: 194 RGRDITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPLE-RLGTPQDIAGAVAFLAGPDG 252 Query: 244 PFLNGEVIRLDGAI 257 ++NG+V+R +G I Sbjct: 253 AWVNGQVLRANGGI 266 >1P33-A nrPDB Length = 289 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 60/282 (21%), Positives = 106/282 (37%), Gaps = 36/282 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQA------KKLGNNCVFAPADV 65 VA++TG A LG + AE L +G + L S +A + N+ + AD+ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTV-CLHYHRSAADASTLAATLNARRPNSAITVQADL 67 Query: 66 TSEKD-----------------VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQT 108 ++ + +GR DV VN A + G+ Sbjct: 68 SNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEG 127 Query: 109 HTLEDFQRVLDV--------NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE 160 + + L+V N + + +I+ A + +Q G I+N + Sbjct: 128 GSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQ 187 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQ 220 +G Y+ +K + G+T A +LA + IRV ++PGL P +P V + Sbjct: 188 PLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--DDMPFSVQEDYRRK 245 Query: 221 VPFPSRLGDPAEYAHLVQAIIE--NPFLNGEVIRLDGAIRMQ 260 VP R E + +V + ++ G I++DG + Sbjct: 246 VPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSLT 287 >1AHH-A nrPDB Length = 255 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 115/256 (44%), Gaps = 20/256 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCVFAPA 63 + G A+ITG +G+G A GAS V+ D+ + ++LG Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 D+TSE+++ A K G+VD+ VN AG + DF+R ++N+ Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-------DMPMADFRRAYELNVF 120 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F++ +LVA EM +N GVI+ S+AA + +Y++SK + +A Sbjct: 121 SFFHLSQLVAPEMEKN------GGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTS-LPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 DL IRV IAPG T L S + ++ + P RLG P + A+ + Sbjct: 175 FDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI-RRLGQPQDIANAALFLCS 233 Query: 243 --NPFLNGEVIRLDGA 256 +++G+++ + G Sbjct: 234 PAASWVSGQILTVSGG 249 >2B4Q-A nrPDB Length = 276 Score = 201 bits (512), Expect = 3e-52, Method: Composition-based stats. Identities = 63/260 (24%), Positives = 116/260 (44%), Gaps = 16/260 (6%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG--NNCVFAPAD 64 S+ G +A++TGG+ G+G A+ L+ GA + A +L +C PAD Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 85 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 ++SE + R+D+ VN AG + + +++ + +++V+ +N+ Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAAL------ESYPVSGWEKVMQLNVTS 139 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-AYSASKGGIVGMTLPIA 183 F+ I+ + + ++ + +IN SVA QA AY SK + ++ +A Sbjct: 140 VFSCIQQLLPLLRRSASAENP--ARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLA 197 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLA--SQVPFPSRLGDPAEYAHLVQAII 241 ++L I V IAPG F + + + A + +P R G P E A L ++ Sbjct: 198 KELVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPM-GRWGRPEEMAALAISLA 256 Query: 242 --ENPFLNGEVIRLDGAIRM 259 ++ G VI +DG + Sbjct: 257 GTAGAYMTGNVIPIDGGFHL 276 >2GDZ-A nrPDB Length = 267 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 33/261 (12%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL-----GNNCVFAP 62 V G VA++TG A G+G A AE L+ +GA L+D G L +F Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV ++ ++ FGR+D+ VN AG+ + +++++ L +NL Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------------NNEKNWEKTLQINL 110 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP- 181 + + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 111 VSVISGTYLGLDYMSKQN---GGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSA 167 Query: 182 -IARDLAPIGIRVMTIAPGLFGTPLLTSLPE--------KVCNFLASQVPFPSRLGDPAE 232 +A +L G+R+ I PG T +L S+ + + + + + + L DP Sbjct: 168 ALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGIL-DPPL 226 Query: 233 YAHLVQAIIENPFLNGEVIRL 253 A+ + +IE+ LNG ++++ Sbjct: 227 IANGLITLIEDDALNGAIMKI 247 >1O5I-A nrPDB Length = 249 Score = 197 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 57/256 (22%), Positives = 100/256 (39%), Gaps = 28/256 (10%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 + ++ + G+G A A+ L +GA + E K+ G+ + D+ + Sbjct: 18 RDKGVLVLAASRGIGRAVADVLSQEGAEVTICARN----EELLKRSGHR--YVVCDLRKD 71 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 L L K VD+ V AG A L T EDF+ +D + + Sbjct: 72 ------LDLLFEKVKEVDILVLNAGGPKAGFFDEL------TNEDFKEAIDSLFLNMIKI 119 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 +R M + G I+ S + ++++ + G ++ ++AP Sbjct: 120 VRNYLPAMKEK------GWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAP 173 Query: 189 IGIRVMTIAPGLFGTPLLTS-LPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NPF 245 GI V +APG T + L E+ + SQ+P R+ P E A +V + + Sbjct: 174 YGITVNCVAPGWTETERVKELLSEEKKKQVESQIPM-RRMAKPEEIASVVAFLCSEKASY 232 Query: 246 LNGEVIRLDGAIRMQP 261 L G+ I +DG + P Sbjct: 233 LTGQTIVVDGGLSKFP 248 >5B1Y-A nrPDB Length = 270 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 64/255 (25%), Positives = 108/255 (42%), Gaps = 24/255 (9%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPN----SGGEAQAKKLG-NNCVFAPADVTS 67 A++TGG+ G+G AT R +G S V+ +A++LG DV Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGD 85 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 V + ++V VN AG+ L + ++ +++ L VNL G + Sbjct: 86 PDSVTEMSSRVGELIPHLNVLVNAAGV------LQLGGIEETSISEWEETLRVNLTGVYL 139 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV-GQAAYSASKGGIVGMTLPIARDL 186 V + + + I+N AS+A G V AYSASK G++G+T +A L Sbjct: 140 VTK------LLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQL 193 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAIIE-- 242 A GIRV +AP T + S + + +AS P + P + A + + + Sbjct: 194 AGYGIRVNAVAPSFVETDMTRSFLDTPEKRERIASLHPL-KIILKPEDVAEAILFLADPR 252 Query: 243 -NPFLNGEVIRLDGA 256 + + G V+ ++ Sbjct: 253 RSRGITGHVLSINAG 267 >3OIC-A nrPDB Length = 258 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 53/259 (20%), Positives = 100/259 (38%), Gaps = 21/259 (8%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE----AQAKKLGNNCVFAPAD 64 + A++TG + G+G A A RL G + V+ + + +KLG + A+ Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 V ++ FGR+DV VN A V L++ + +++N Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETH------WDWTMNINAKA 116 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + A M +N G I++ +S+ + SK + +T +A Sbjct: 117 LLFCAQEAAKLMEKN------GGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAV 170 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSLP--EKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 +L+P I V ++ G T L P E + P R+ + + V+ ++ Sbjct: 171 ELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTP-AGRMVEIKDMVDTVEFLVS 229 Query: 243 N--PFLNGEVIRLDGAIRM 259 + + G+ I +DG + Sbjct: 230 SKADMIRGQTIIVDGGRSL 248 >4AVY-A nrPDB Length = 242 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 77/253 (30%), Positives = 108/253 (42%), Gaps = 27/253 (10%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 G ++TGG+SG+G A A + GA V L L G A D+T Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAP---RHPRIRREELDITDS 66 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 + +Q R+DV VN AGI+ + Y+L F+RVL +NL Sbjct: 67 QRLQRLFEA----LPRLDVLVNNAGISRDREEYDLAT--------FERVLRLNLSAAMLA 114 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 +L + Q + G I+N AS+ + G + AYSASKG IV +T +A + A Sbjct: 115 SQLARPLLAQ-------RGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAA 167 Query: 189 IGIRVMTIAPGLFGTPLLTSLPEKVCN--FLASQVPFPSRLGDPAEYAHLVQAII--ENP 244 IRV IAPG TPL L V + + P R G+ E A + Sbjct: 168 ERIRVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLA-RWGEAPEVASAAAFLCGPGAS 226 Query: 245 FLNGEVIRLDGAI 257 F+ G V+ +DG Sbjct: 227 FVTGAVLAVDGGY 239 >4FC7-A nrPDB Length = 277 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 113/258 (43%), Gaps = 22/258 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN----SGGEAQAKKLGNNCVFAPA 63 ++ VA ITGG SG+G AE + G V+ + A G C+ Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 84 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV + V A+ A +FGR+D+ +NCA L + F+ V+D++ Sbjct: 85 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNF------LCPAGALSFNAFKTVMDIDTS 138 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GTFNV R++ + ++ GVI+N + GQ Q ++K + MT +A Sbjct: 139 GTFNVSRVLYEKFFRDH------GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 192 Query: 184 RDLAPIGIRVMTIAPGLF-GTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 + P IRV ++APG GT L L P+ + + P RLG+ E AH V + Sbjct: 193 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSVLYL 251 Query: 241 IE--NPFLNGEVIRLDGA 256 ++ G V+ DG Sbjct: 252 ASPLASYVTGAVLVADGG 269 >5JS6-A nrPDB Length = 274 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 112/240 (46%), Gaps = 19/240 (7%) Query: 27 AERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVD 86 V GA V+ D SGG A ++L VF DVT E DV+T ++ +FGR+D Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVTQEDDVKTLVSETIRRFGRLD 86 Query: 87 VAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQ 146 VN AG ++ + + + F+++L++NL+GT+ + +L + +++ Sbjct: 87 CVVNNAGHHPPP-----QRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ------ 135 Query: 147 RGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLL 206 G +IN +S+ GQ Y A+KG + MT +A D +P G+RV I+PG TPL Sbjct: 136 -GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLW 194 Query: 207 TSL----PEKVCNFLASQVPFP-SRLGDPAEYAHLVQAII-ENPFLNGEVIRLDGAIRMQ 260 L P+ + P R+G PAE + E F G + + G + Sbjct: 195 EELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELG 254 >4TRR-A nrPDB Length = 269 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 66/272 (24%), Positives = 119/272 (43%), Gaps = 27/272 (9%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFA 61 ++ G AV+TG ASG+G A L GA+ + DL G A A ++ G + Sbjct: 9 MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGV 68 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 DVT+E+ V T + FG VD+ V+ AGI + + N ++ D++++ ++ Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIEN------YSFADWKKMQAIH 122 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + G F + M +++ + GV+I SV + E ++AY +K G++G+ Sbjct: 123 VDGAFLTTKAALKHMYKDD-----RGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARV 177 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLT-SLPEKVCNFLASQVPFPSR----------LGDP 230 +A++ A +R + PG TPL+ +PE+ S+ + Sbjct: 178 LAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTV 237 Query: 231 AEYAHLVQAIIE--NPFLNGEVIRLDGAIRMQ 260 + A V + + L G+ + MQ Sbjct: 238 QDVAQTVLFLSAFPSAALTGQSFIVSHGWFMQ 269 >3ZV3-A nrPDB Length = 281 Score = 190 bits (483), Expect = 5e-49, Method: Composition-based stats. Identities = 70/263 (26%), Positives = 104/263 (39%), Gaps = 21/263 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G VA+ITGGASGLG A +R V +GA +LD G N V DV Sbjct: 2 KLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVR 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 S +D + A FG++D + AGI S + F + VN+ G Sbjct: 62 SLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLP-EDKIDAAFDDIFHVNVKGYI 120 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + ++ + RG ++ T S A F G Y+A+K +VG+ +A +L Sbjct: 121 HAVKACLPALV-------SSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFEL 173 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFP---------SRLGDPAEYAHLV 237 AP +RV +APG T L + S VP R+ EY Sbjct: 174 APH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAY 232 Query: 238 QAII---ENPFLNGEVIRLDGAI 257 ++ G ++ DG + Sbjct: 233 VFFATRGDSLPATGALLNYDGGM 255 >3GDF-A nrPDB Length = 267 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 59/263 (22%), Positives = 105/263 (39%), Gaps = 25/263 (9%) Query: 7 SVKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNSGGEAQ-----AKKLGNNCV 59 S+KG V V+TG + G+G+ A GA+ + + G + K G Sbjct: 17 SLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAK 76 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 V S + + + FG++D + AG S + ++E + V+ Sbjct: 77 AYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILD------GSVEAWNHVVQ 130 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV--GQAAYSASKGGIVG 177 V+L GTF+ + V + G ++ TAS++ Q +Y+ +K G + Sbjct: 131 VDLNGTFHCAKAVGHHFKER------GTGSLVITASMSGHIANFPQEQTSYNVAKAGCIH 184 Query: 178 MTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEY--AH 235 M +A + RV +I+PG T L +P++ S +P R G E A+ Sbjct: 185 MARSLANEWRDFA-RVNSISPGYIDTGLSDFVPKETQQLWHSMIPM-GRDGLAKELKGAY 242 Query: 236 LVQAIIENPFLNGEVIRLDGAIR 258 + A + + G + +DG Sbjct: 243 VYFASDASTYTTGADLLIDGGYT 265 >2AG5-A nrPDB Length = 246 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 62/265 (23%), Positives = 107/265 (40%), Gaps = 28/265 (10%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + G V ++T A G+G A A +GA + D+ S + K G D Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--D 58 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 VT +K + + R+DV N AG + ++ +D+ +++N+ Sbjct: 59 VTKKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEE------KDWDFSMNLNVRS 108 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPIA 183 + +I+ +M + G IIN +SVA+ +G V + YS +K ++G+T +A Sbjct: 109 MYLMIKAFLPKMLAQ------KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA 162 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTS------LPEKVCNFLASQVPFPSRLGDPAEYAHLV 237 D GIR + PG TP L PE+ N + R E A L Sbjct: 163 ADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKR-QKTGRFATAEEIAMLC 221 Query: 238 QAIIEN--PFLNGEVIRLDGAIRMQ 260 + + ++ G + +DG + Sbjct: 222 VYLASDESAYVTGNPVIIDGGWSLG 246 >2BGM-A nrPDB Length = 278 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 63/241 (26%), Positives = 113/241 (46%), Gaps = 19/241 (7%) Query: 27 AERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV--FAPADVTSEKDVQTALALAKGKFGR 84 A+ V GA V+ D+ + G+ +G+ V F DVT ++DV+ + K G+ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 85 VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQG 144 +D+ G+ + L+ G EDF+RV+D+N+ G F V + A M Sbjct: 93 LDIMFGNVGVLSTTPYSILEAGN----EDFKRVMDINVYGAFLVAKHAARVMI------P 142 Query: 145 GQRGVIINTASVAAFEGQVGQAA-YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGT 203 ++G I+ TAS+++F G + Y+A+K ++G+T + +L GIRV ++P + + Sbjct: 143 AKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVAS 202 Query: 204 PLLTSL----PEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENPFLNGEVIRLDGAI 257 PLLT + +V L + A V + E+ +++G + +DG Sbjct: 203 PLLTDVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGY 262 Query: 258 R 258 Sbjct: 263 T 263 >1H5Q-A nrPDB Length = 265 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 65/268 (24%), Positives = 110/268 (41%), Gaps = 25/268 (9%) Query: 2 AAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG----EAQAKKLGNN 57 S ++TGG G+GLA + GA+ ++ + E K+ G Sbjct: 6 PGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVK 65 Query: 58 CVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRV 117 DV++ V + G + + AG++V +K T EDF V Sbjct: 66 TKAYQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSV------VKPATELTHEDFAFV 119 Query: 118 LDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA-------FEGQVGQAAYSA 170 DVN+ G FN R VA Q + Q+G I+ T+S+++ G + Q Y++ Sbjct: 120 YDVNVFGVFNTCRAVAKLWLQKQ-----QKGSIVVTSSMSSQIINQSSLNGSLTQVFYNS 174 Query: 171 SKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDP 230 SK + +A + A GIRV ++PG T + +K+ + AS +P +R P Sbjct: 175 SKAACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPL-NRFAQP 233 Query: 231 AEYAHLVQAIIEN--PFLNGEVIRLDGA 256 E ++ + ++ G +DG Sbjct: 234 EEMTGQAILLLSDHATYMTGGEYFIDGG 261 >3UN1-A nrPDB Length = 260 Score = 186 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 61/246 (24%), Positives = 103/246 (41%), Gaps = 20/246 (8%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 V VITG + G+G + V + D++ + Sbjct: 29 KVVVITGASQGIGAGLVRAYRDRNYRVVATSRS------IKPSADPDIHTVAGDISKPET 82 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 + +FGR+D VN AG+ +A + T ED+ L VN+ G F++ + Sbjct: 83 ADRIVREGIERFGRIDSLVNNAGVFLAKPFVEM------TQEDYDHNLGVNVAGFFHITQ 136 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 A EM + QG V I T+ V + A S +KGG+ +T +A + + G Sbjct: 137 RAAAEMLK----QGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSG 192 Query: 191 IRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEV 250 +RV ++PG+ TP+ P + + LA P R+G+ + V + F+ GE+ Sbjct: 193 VRVNAVSPGVIKTPM---HPAETHSTLAGLHPV-GRMGEIRDVVDAVLYLEHAGFITGEI 248 Query: 251 IRLDGA 256 + +DG Sbjct: 249 LHVDGG 254 >4CR6-A nrPDB Length = 271 Score = 186 bits (473), Expect = 7e-48, Method: Composition-based stats. Identities = 79/255 (30%), Positives = 114/255 (44%), Gaps = 10/255 (3%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + G A++TG A G+G AT E + +GAS V +DL + ++ G + D+ Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG--AIPIACDLA 69 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + A+A A + G +D+ V AG A+ T N + D+ R +DVN+ GTF Sbjct: 70 DRAAIDAAMADAVARLGGLDILV--AGGALKGGTGNFLD---LSDADWDRYVDVNMTGTF 124 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R A M + G+ II SV +F + AAY A+KGG+ +T +A DL Sbjct: 125 LTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDL 184 Query: 187 APIGIRVMTIAPGLFG-TPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 A GI V IAPG T T E R G P E A + E+ Sbjct: 185 ARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAEDGS 244 Query: 244 PFLNGEVIRLDGAIR 258 F+ G I +DG + Sbjct: 245 SFITGSTITIDGGLS 259 >3D3W-A nrPDB Length = 244 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 50/254 (19%), Positives = 100/254 (39%), Gaps = 21/254 (8%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G ++TG G+G T + L GA V + + ++ ++ D+ Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG-IEPVCVDLGD 63 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 + + AL G VD+ VN A +A+ + T E F R +VNL Sbjct: 64 WEATERALGSV----GPVDLLVNNAAVALLQPFLEV------TKEAFDRSFEVNLRAVIQ 113 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V ++VA + G G I+N +S + + Y ++KG + +T +A +L Sbjct: 114 VSQIVARGLIAR-----GVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELG 168 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEK--VCNFLASQVPFPSRLGDPAEYAHLVQAIIEN-- 243 P IRV + P + T + + + +++P + + + + ++ + Sbjct: 169 PHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPL-GKFAEVEHVVNAILFLLSDRS 227 Query: 244 PFLNGEVIRLDGAI 257 G + ++G Sbjct: 228 GMTTGSTLPVEGGF 241 >3UF0-A nrPDB Length = 273 Score = 186 bits (472), Expect = 9e-48, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 108/257 (42%), Gaps = 20/257 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN--SGGEAQAKKLGNNCVFAPAD 64 S+ G AV+TG SG+G A A GA + + + G + AD Sbjct: 28 SLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVAD 87 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 + + RVDV VN AGI + + G+ ++ VL VNL Sbjct: 88 LADLEGAANVAEELAATR-RVDVLVNNAGIIARAPAEEVSLGR------WREVLTVNLDA 140 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + + R M + G I+ AS+ +F+G AAY+ASK +VG+T +A Sbjct: 141 AWVLSRSFGTAMLAH------GSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALAS 194 Query: 185 DLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE 242 + A G+ V +APG T +L ++ + +++P R P + + Sbjct: 195 EWAGRGVGVNALAPGYVVTANTAALRADDERAAEITARIP-AGRWATPEDMVGPAVFLAS 253 Query: 243 N--PFLNGEVIRLDGAI 257 + +++G+V+ +DG Sbjct: 254 DAASYVHGQVLAVDGGW 270 >5IZ4-A nrPDB Length = 271 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 76/261 (29%), Positives = 120/261 (45%), Gaps = 19/261 (7%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSG------GEAQAKKLGNNCVFAPADV 65 V VITG ASG+G ATA R G S + + +S EA + G + ADV Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + D + A+ + ++ R+D +NCAG + +F+RV VNL+G Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDF---EFERVYRVNLIGL 132 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + + R + E + ++N +S+A G AY+ASKG + +TL +AR+ Sbjct: 133 YQMTRAAVPLL--RESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARN 190 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEK-----VCNFLASQVPFPSRLGDPAEYAHLVQAI 240 LAP IRV +APG+ LL + + V + + P R+ PAE A L + Sbjct: 191 LAPH-IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPL-KRVSRPAEIAELAWFL 248 Query: 241 -IENPFLNGEVIRLDGAIRMQ 260 P + G+VI + + + Sbjct: 249 TAHAPAITGQVIAAENGLLLG 269 >5JY1-A nrPDB Length = 274 Score = 183 bits (465), Expect = 6e-47, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 116/260 (44%), Gaps = 20/260 (7%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG---EAQAKKLGNNCVFAPAD 64 ++ VA++TG G+G A +GA+ ++ ++ S G E + +++G +F D Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 124 VTS+ ++ A+ A +FG +D+ VN A + + + T E ++ L +L Sbjct: 72 VTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLL-----EEKTDEMLEQTLTTSLWA 126 Query: 125 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T+ +R M + + G I+N S+ G Y+ +K GIVG+T A Sbjct: 127 TWWAMRAAFVPMRER------RWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAAS 180 Query: 185 DLAPIGIRVMTIAPGLFGTPL--LTSLPEKVCNFLASQVPFPSRLGDPAE---YAHLVQA 239 + I V IAP G L + + A+ P R GDP + A + A Sbjct: 181 EWGRFNITVNAIAPTAMGATFFELAAKNPEFAERSAAARPL-GRSGDPEQDIGPAAVFFA 239 Query: 240 IIENPFLNGEVIRLDGAIRM 259 + F+ GE + +DG + + Sbjct: 240 SEMSRFVTGETLHVDGGLHL 259 >1BDB-A nrPDB Length = 277 Score = 183 bits (464), Expect = 8e-47, Method: Composition-based stats. Identities = 65/263 (24%), Positives = 106/263 (40%), Gaps = 21/263 (7%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 +KG +ITGGASGLG A +R V +GA +LD G+N + DV Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVR 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 S +D + A + +FG++D + AGI S + + F V +N+ G Sbjct: 62 SLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTAL-VDLPEESLDAAFDEVFHINVKGYI 120 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + ++ + + RG +I T S A F G Y+A+K IVG+ +A +L Sbjct: 121 HAVKACLPALVAS-------RGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFEL 173 Query: 187 APIGIRVMTIAPGLFGTPL---------LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237 AP +RV + G + L ++ + V R+ + EY Sbjct: 174 APY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAY 232 Query: 238 QAII---ENPFLNGEVIRLDGAI 257 + G ++ DG + Sbjct: 233 VFFATRGDAAPATGALLNYDGGL 255 >1CYD-A nrPDB Length = 244 Score = 181 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 61/255 (23%), Positives = 104/255 (40%), Gaps = 21/255 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 + GL A++TG G+G T + L GA V + NS + AK+ D+ Sbjct: 4 NFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG-IEPVCVDLG 62 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + AL G VD+ VN A + + + T E F R VNL F Sbjct: 63 DWDATEKALGGI----GPVDLLVNNAALVIMQPFLEV------TKEAFDRSFSVNLRSVF 112 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 V ++VA +M G G I+N +S+ A YS++KG + +T +A +L Sbjct: 113 QVSQMVARDMINR-----GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMEL 167 Query: 187 APIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN- 243 P IRV ++ P + T + + + L + P + + + + + ++ + Sbjct: 168 GPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPL-RKFAEVEDVVNSILFLLSDR 226 Query: 244 -PFLNGEVIRLDGAI 257 +G I +D Sbjct: 227 SASTSGGGILVDAGY 241 >5O3Z-A nrPDB Length = 263 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 75/268 (27%), Positives = 108/268 (40%), Gaps = 31/268 (11%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL-----GNNCVFAPADVT 66 VAV+ GG LG E L G + DL S A + D T Sbjct: 8 VAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDAT 67 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E V+ FGR D+ V AG+A A+ + L DF L VNL+G F Sbjct: 68 DEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFR------LTDFDLSLQVNLVGYF 121 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R + M ++ G +G II S + G + YSA+K G VG+T +A DL Sbjct: 122 LCSREFSKLMIRD-----GIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDL 176 Query: 187 APIGIRVMTIAPG-LFGTPLLTSL-----------PEKVCNFLASQVPFPSRLGDPAEYA 234 A GI V ++ G L +P+ SL PE+V + +VP R D + Sbjct: 177 AEYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPL-KRGCDYQDVL 235 Query: 235 HLVQAIIENP--FLNGEVIRLDGAIRMQ 260 +++ + + G+ I + G M Sbjct: 236 NVLLFYASDKAAYCTGQSINVTGGQVMF 263 >4RGB-A nrPDB Length = 294 Score = 177 bits (449), Expect = 4e-45, Method: Composition-based stats. Identities = 70/286 (24%), Positives = 119/286 (41%), Gaps = 42/286 (14%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL------------PNSGGEAQA- 51 S+ G V ITG A G G + A QGA+ V +D+ E A Sbjct: 20 MGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETAR 79 Query: 52 --KKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109 +K G +F ADV + +Q +FG +D + AG+ + + Sbjct: 80 LVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDER------D 133 Query: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE----GQVGQ 165 E + LD+ L+G +N ++ M + GQ G +I T+S+ A G+ G Sbjct: 134 ASEALRLGLDIMLIGVWNTFQVAIPHMKER-----GQGGNLIATSSMIALLDLTDGRGGT 188 Query: 166 AAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE---------KVCNF 216 AY SK I G+ A LA IRV +AP TP++T P + N Sbjct: 189 DAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNA 248 Query: 217 LASQVPFPSRLGDPAEYAHLVQAIIENP--FLNGEVIRLDGAIRMQ 260 +++ +P + +P + ++ + +I + G V+++D + ++ Sbjct: 249 MSTALPDF-PMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVK 293 >2FWM-X nrPDB Length = 250 Score = 176 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 59/266 (22%), Positives = 100/266 (37%), Gaps = 32/266 (12%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 G +TG G+G ATA V GA D + + DV Sbjct: 4 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQ-------YPFATEVMDVA 56 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 V + R+D VN AGI + + ED+Q+ VN+ G F Sbjct: 57 DAAQVAQVCQRLLAETERLDALVNAAGI------LRMGATDQLSKEDWQQTFAVNVGGAF 110 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N+ + + + + G I+ AS AA ++G +AY ASK + + L + +L Sbjct: 111 NLFQQTMNQFRRQ------RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLEL 164 Query: 187 APIGIRVMTIAPGLFGTPLLTSLP-----EKVC-----NFLASQVPFPSRLGDPAEYAHL 236 A G+R ++PG T + +L E+ +P ++ P E A+ Sbjct: 165 AGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEIANT 223 Query: 237 VQAIIEN--PFLNGEVIRLDGAIRMQ 260 + + + + + I +DG + Sbjct: 224 ILFLASDLASHITLQDIVVDGGSTLG 249 >4DA9-A nrPDB Length = 280 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 109/255 (42%), Gaps = 13/255 (5%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK----LGNNCVFAPADVTS 67 VA++TGG G+GL A L G + + ++ G A LG +F AD+ Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 68 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 Q + +FGR+D VN AGIA + E+F ++ VNL GT Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRD----DFLDLKPENFDTIVGVNLRGTVF 146 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + V M ++ IIN SV+A + Y SK G+ + +A LA Sbjct: 147 FTQAVLKAMLASDARASR---SIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLA 203 Query: 188 PIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENPF 245 GI V + PG+ + + ++ K + S + R G+P + ++V + + F Sbjct: 204 ETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLVPMRRWGEPEDIGNIVAGLAGGQFGF 263 Query: 246 LNGEVIRLDGAIRMQ 260 G VI+ DG + + Sbjct: 264 ATGSVIQADGGLSIG 278 >3V8B-A nrPDB Length = 283 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 68/264 (25%), Positives = 110/264 (41%), Gaps = 28/264 (10%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 VA+ITG SG+G ATA L G + L + E A ++ G + ADV+ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGI-AVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 ++ A+ KFG +D+ V AGI V + +LK + + + VNL GTF Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFE------WDETIAVNLRGTFL 143 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEG--QVGQAAYSASKGGIVGMTLPIARD 185 + L + Q G I+ +S+ G AY+A+K V + +A + Sbjct: 144 TLHLTVPYLKQR------GGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALE 197 Query: 186 LAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLA-------SQVPFP-SRLGDPAEYAHLV 237 L IRV + PG T + + + A QVP + G + A L+ Sbjct: 198 LGKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELI 257 Query: 238 QAIIE--NPFLNGEVIRLDGAIRM 259 + ++ + G + +DG + Sbjct: 258 RFLVSERARHVTGSPVWIDGGQGL 281 >3OML-A nrPDB Length = 613 Score = 171 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 62/245 (25%), Positives = 94/245 (38%), Gaps = 32/245 (13%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDL---------PNSGGEAQAKKLGNNCV 59 G VAV+TG +GLG A +GA V+ DL + ++ Sbjct: 18 DGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGG 77 Query: 60 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 A AD S D + A FGRVD+ VN AGI + +D+ V D Sbjct: 78 EAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVK------TSEQDWNLVND 131 Query: 120 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 V+L G+F + M + G II T+S + G GQ Y+A+K G++G+ Sbjct: 132 VHLKGSFKCTQAAFPYMKKQN------YGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLA 185 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 +A + A + I P LP+ + N L ++ A +V Sbjct: 186 NTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKL-----------IAPVVAY 234 Query: 240 IIENP 244 + Sbjct: 235 LCHES 239 >4EGF-A nrPDB Length = 266 Score = 168 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 70/266 (26%), Positives = 101/266 (37%), Gaps = 20/266 (7%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----NC 58 A + G A+ITG G+G A GA VL S +A + LG + Sbjct: 13 AGVLRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDV 72 Query: 59 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 D+ A FG +DV VN AGI+ + + F + Sbjct: 73 HTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDP------QLFDATI 126 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 VNL + V M G+ G II AS AA AY SK G+V Sbjct: 127 AVNLRAPALLASAVGKAMVA-----AGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMA 181 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHL 236 T +AR+L P GIR ++ P + T + + E + +++P R P E + Sbjct: 182 TKVLARELGPHGIRANSVCPTVVLTEMGQRVWGDEAKSAPMIARIPL-GRFAVPHEVSDA 240 Query: 237 VQAIIEN--PFLNGEVIRLDGAIRMQ 260 V + + +NG I +DG M Sbjct: 241 VVWLASDAASMINGVDIPVDGGYTMG 266 >3PXX-A nrPDB Length = 287 Score = 167 bits (423), Expect = 5e-42, Method: Composition-based stats. Identities = 66/301 (21%), Positives = 104/301 (34%), Gaps = 58/301 (19%) Query: 2 AAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLD---------------LPNSG 46 + V+ V ++TGGA G G + A +L +GA +L D Sbjct: 2 PGSMGRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEE 61 Query: 47 GEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKG 106 + +K G A DV V LA A +FG++DV V AGI G Sbjct: 62 AGLEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGI--------CPLG 113 Query: 107 QTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE------ 160 ++ F DV+ +G N + + II T SVA Sbjct: 114 AHLPVQAFADAFDVDFVGVINTVHAALPYLT--------SGASIITTGSVAGLIAAAQPP 165 Query: 161 -----GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLP----- 210 G A YS +K + TL +A LAP IR I P T +L S P Sbjct: 166 GAGGPQGPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQF 225 Query: 211 ---------EKVCNFLASQVPFPSRLGDPAEYAHLVQAIIEN--PFLNGEVIRLDGAIRM 259 + P+ + ++ ++ V + + ++ G ++D + Sbjct: 226 RPDLEAPSRADALLAFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 Query: 260 Q 260 + Sbjct: 286 K 286 >4GKB-A nrPDB Length = 258 Score = 166 bits (421), Expect = 8e-42, Method: Composition-based stats. Identities = 69/263 (26%), Positives = 110/263 (41%), Gaps = 26/263 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG---EAQAKKLGNNCVFAPA 63 +++ V ++TGGASG+G A + RL + A V+ G +A A++ + P Sbjct: 4 NLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQR-QPRATYLPV 62 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 ++ + + A+A FGR+D VN AG+ N G + F L+ NL+ Sbjct: 63 ELQDDAQCRDAVAQTIATFGRLDGLVNNAGV-------NDGIGLDAGRDAFVASLERNLI 115 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + + RG I+N +S A GQ + Y ASKG + +T A Sbjct: 116 HYYAMAHYCVPHLKAT-------RGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWA 168 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSL------PEKVCNFLASQVPFPSRLGDPAEYAHLV 237 L G+RV + P TPL + PE +A++VP R P E A Sbjct: 169 VALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTA 228 Query: 238 QAIIE--NPFLNGEVIRLDGAIR 258 ++ GE + +DG Sbjct: 229 VFLLSPRASHTTGEWLFVDGGYT 251 >5ILO-A nrPDB Length = 271 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 64/213 (30%), Positives = 100/213 (46%), Gaps = 23/213 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGA-SAVLLDLPNSGGE---AQAKKLGNNCVFAP 62 S +G AV+TGGA G+GL +++L+ GA ++DL ++ E +A + + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV ++K V+ FG +D+ VN AGI D QR L VNL Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDK--------------DVQRTLLVNL 117 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G N MG+ D GG+ G+++N +SV + Y A+K GI+ T + Sbjct: 118 GGIINSTLSALPYMGK---DNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCL 174 Query: 183 ARD--LAPIGIRVMTIAPGLFGTPLLTSLPEKV 213 A + GI+ +T+ PG T + T+ EK+ Sbjct: 175 ANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKI 207 >3RKU-A nrPDB Length = 287 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 57/248 (22%), Positives = 90/248 (36%), Gaps = 28/248 (11%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQ---GASAVLLDLPNSGGEAQAKKL-----G 55 A + +ITG ++G+G ATA + +L E K + Sbjct: 27 AAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPN 86 Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 A D+T + ++ + +F +D+ VN AG A+ S + ED Q Sbjct: 87 AKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSD-----RVGQIATEDIQ 141 Query: 116 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 V D N+ N+ + V Q G I+N S+A + + Y ASK + Sbjct: 142 DVFDTNVTALINITQAVLPIF------QAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAV 195 Query: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPL----LTSLPEKVCNFLASQVPFPSRLGDPA 231 T + ++L IRV+ IAPGL T E+ N P Sbjct: 196 GAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLM-----AD 250 Query: 232 EYAHLVQA 239 + A L+ Sbjct: 251 DVADLIVY 258 >2NWQ-A nrPDB Length = 272 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 56/233 (24%), Positives = 86/233 (36%), Gaps = 21/233 (9%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA--DVTSEKDV 71 ITG SG G A A R G S VL +A A +L P DV + Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRAAM 84 Query: 72 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 A+ +F + +N AG+A+ + Q+ L+D+ ++D N+ G RL Sbjct: 85 SAAVDNLPEEFATLRGLINNAGLALGTD-----PAQSCDLDDWDTMVDTNIKGLLYSTRL 139 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 + + + G I+N SVA G Y +K + +L + DL G+ Sbjct: 140 LLPRLIAH-----GAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGV 194 Query: 192 RVMTIAPGLFGTPL----LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 RV + PGL + + A P P + A + I Sbjct: 195 RVTNLEPGLCESEFSLVRFGGDQARYDKTYAGAHPI-----QPEDIAETIFWI 242 >4HBG-A nrPDB Length = 286 Score = 150 bits (378), Expect = 8e-37, Method: Composition-based stats. Identities = 63/272 (23%), Positives = 106/272 (38%), Gaps = 50/272 (18%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG---------NNCVFAP 62 VA++TG G+G A ++L +G S ++L E A G C A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 63 --------ADVTSEKDVQ------------TALALAKGKFGR------VDVAVNCAGIAV 96 D S ++ + L K+ V++ +NCAG+ Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 97 ASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNE---PDQGGQRGV--II 151 S + T Q +++VN M + + M +++ P+ GQ I+ Sbjct: 126 ESLSVR------TTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 Query: 152 NTASV--AAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG-TPLLTS 208 N +S+ + G + YSASK + T +A ++ P IR TI+PGL T ++ + Sbjct: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 Query: 209 LPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 LP + L + PAE A V ++ Sbjct: 240 LPVEAKEMLERTIGASG-TSAPAEIAEEVWSL 270 >3U4C-A nrPDB Length = 281 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 57/266 (21%), Positives = 92/266 (34%), Gaps = 35/266 (13%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFAPADV 65 A + G + G+G A A +L Q S V+ E+ AK + + D+ Sbjct: 24 RTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDM 83 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + + + + GR+DV +N +ED + Sbjct: 84 SDQHTRAGIFQKIESQCGRLDVLINN------IPGGAPDTFDNCNIEDMTATFTQKTVAY 137 Query: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS--KGGIVGMTLPIA 183 + I+ + M QNE G IIN V + G ++ S ++ + I+ Sbjct: 138 IDAIKRASSLMKQNE------FGRIINI--VGNLWKEPGANMFTNSMMNAALINASKNIS 189 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLPE-----------KVCNFLASQVPFPSRLGDPAE 232 LAP I V + PG T E K +AS +P R+G E Sbjct: 190 IQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPM-KRVGSAEE 248 Query: 233 YAHLVQAII--ENPFLNGEVIRLDGA 256 A L + E ++ G+ I DG Sbjct: 249 TAALAAFLASEEASYITGQQISADGG 274 >4DRY-A nrPDB Length = 281 Score = 145 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 61/251 (24%), Positives = 93/251 (37%), Gaps = 25/251 (9%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN--- 57 MA S +G +A++TGG +G+G A+ L +G S V+ +A A ++G Sbjct: 24 MAQGKGSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGN 83 Query: 58 -CVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQR 116 DV V A + +F R+D+ VN AG V + T E + Sbjct: 84 IVRAVVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPV-----PLEEVTFEQWNG 138 Query: 117 VLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 ++ NL G F + M P + G IIN S++A + A Y+A+K I Sbjct: 139 IVAANLTGAFLCTQHAFRMMKAQTP----RGGRIINNGSISAQTPRPNSAPYTATKHAIT 194 Query: 177 GMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCN-----FLASQVPFPSRLGDPA 231 G+T A D I I G T + + V +P Sbjct: 195 GLTKSTALDGRMHDIACGQIDIGNAATDMTARMSTGVLQANGEVAAEPTIPI-------E 247 Query: 232 EYAHLVQAIIE 242 A V + Sbjct: 248 HIAEAVVYMAS 258 >1W73-A nrPDB Length = 302 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 60/260 (23%), Positives = 104/260 (40%), Gaps = 21/260 (8%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFA 61 S +G VA ITGG +GLG L GA V+ +A A+++ GN Sbjct: 22 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAI 81 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 DV VQ ++ G ++ +N A S T L ++ + D+ Sbjct: 82 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN------AWKTITDIV 135 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L GT V + ++ + + + ++ ++ A G +++K G+ M+ Sbjct: 136 LNGTAFVTLEIGKQLIKAQ-----KGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKS 190 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV---CNFLASQVPFPSRLGDPAEYAHLVQ 238 +A + G+R I PG T S + + ++P RLG E A+L Sbjct: 191 LAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIP-CGRLGTVEELANLAA 249 Query: 239 AIIEN--PFLNGEVIRLDGA 256 + + ++NG VI+ DG Sbjct: 250 FLCSDYASWINGAVIKFDGG 269 >1A27-A nrPDB Length = 289 Score = 136 bits (344), Expect = 8e-33, Method: Composition-based stats. Identities = 64/252 (25%), Positives = 97/252 (38%), Gaps = 39/252 (15%) Query: 12 VAVITGGASGLGLATAERLVGQGA-----SAVLLDLPNSGGEAQAKKL----GNNCVFAP 62 V +ITG +SG+GL A RL + A L DL G +A + + Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV K V A GRVDV V AG+ + L + + VLDVN+ Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 115 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +GT +++ +M + G ++ T SV G Y ASK + G+ + Sbjct: 116 VGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 169 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSL---PEKVCNF--LASQVPFPSRLG--------- 228 A L P G+ + I G T + + PE+V + + + F L Sbjct: 170 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREA 229 Query: 229 --DPAEYAHLVQ 238 +P E A + Sbjct: 230 AQNPEEVAEVFL 241 >6CGE-A nrPDB Length = 328 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 64/252 (25%), Positives = 97/252 (38%), Gaps = 39/252 (15%) Query: 12 VAVITGGASGLGLATAERLVGQGA-----SAVLLDLPNSGGEAQAKKL----GNNCVFAP 62 V +ITG +SG+GL A RL + A L DL G +A + + Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV K V A GRVDV V AG+ + L + + VLDVN+ Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 116 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +GT +++ +M + G ++ T SV G Y ASK + G+ + Sbjct: 117 VGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSL---PEKVCNF--LASQVPFPSRLG--------- 228 A L P G+ + I G T + + PE+V + + + F L Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREA 230 Query: 229 --DPAEYAHLVQ 238 +P E A + Sbjct: 231 AQNPEEVAEVFL 242 >2P91-A nrPDB Length = 285 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 48/262 (18%), Positives = 95/262 (36%), Gaps = 22/262 (8%) Query: 8 VKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLP---NSGGEAQAKKLGNNCVFAP 62 ++G A+ITG A + A+ +GA AK G++ + Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSD-LVVK 77 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV+ ++D++ + +G +D+ V+ IA A K + E F+ +D+++ Sbjct: 78 CDVSLDEDIKNLKKFLEENWGSLDIIVHS--IAYAPKEEFKGGVIDTSREGFKIAMDISV 135 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + R + M G+ G I+ + A + +K + + Sbjct: 136 YSLIALTRELLPLME-------GRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYL 188 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDP---AEYAHLVQA 239 A D+A G R+ I+ G T L + + L + G P + Sbjct: 189 AYDIAKHGHRINAISAGPVKT--LAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVF 246 Query: 240 IIEN--PFLNGEVIRLDGAIRM 259 + + + GEV+ +D + Sbjct: 247 LCSDWARAITGEVVHVDNGYHI 268 >2YW9-A nrPDB Length = 261 Score = 129 bits (326), Expect = 8e-31, Method: Composition-based stats. Identities = 58/262 (22%), Positives = 99/262 (37%), Gaps = 21/262 (8%) Query: 7 SVKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNNCVFA 61 + G A++ G LG A A +L GA L E A+ LG + Sbjct: 5 DLSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGG-ALLF 63 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 ADVT ++++ A K FG +D V+ IA A + + +D+ L+V+ Sbjct: 64 RADVTQDEELDALFAGVKEAFGGLDYLVH--AIAFAPREAMEGRYIDTRRQDWLLALEVS 121 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 V R + + G I+ A+ + + +K + Sbjct: 122 AYSLVAVARRAEPLLRE--------GGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRY 173 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQA 239 +A +L P G+RV I+ G T S+P K+ + +A P R E +L Sbjct: 174 LAYELGPKGVRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPL-RRNITQEEVGNLGLF 232 Query: 240 IIE--NPFLNGEVIRLDGAIRM 259 ++ + GEV+ +D + Sbjct: 233 LLSPLASGITGEVVYVDAGYHI 254 >2DKN-A nrPDB Length = 255 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 62/262 (23%), Positives = 100/262 (38%), Gaps = 34/262 (12%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 V ITG ASG+G A E L G + + +D + EA D+++ Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEA--------------DLSTPGGR 48 Query: 72 QTALALAKGKFGR-VDVAVNCAGIAVASKTYNL-----KKGQTHTLEDFQRVLDVN---- 121 +TA+A + G +D V CAG+ V + L G + L+ L Sbjct: 49 ETAVAAVLDRCGGVLDGLVCCAGVGVTAANSGLVVAVNYFGVSALLDGLAEALSRGQQPA 108 Query: 122 --LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 ++G+ + A E+ E G I A AY+ SK + + Sbjct: 109 AVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQT----HLAYAGSKYAVTCLA 164 Query: 180 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVC--NFLASQVPFPSRLGDPAEYAHLV 237 D A G+R+ +APG TPLL + V R +P E A + Sbjct: 165 RRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEPREVAEAI 224 Query: 238 QAII--ENPFLNGEVIRLDGAI 257 ++ + F++G V+ +DG + Sbjct: 225 AFLLGPQASFIHGSVLFVDGGM 246 >1B15-A nrPDB Length = 254 Score = 128 bits (322), Expect = 3e-30, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 98/258 (37%), Gaps = 28/258 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGAS-AVLLDL---PNSGGEAQAKKLGNNCVFAP 62 + + G+GL T+ LV + V+LD P + E +A N F Sbjct: 2 DLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHT 61 Query: 63 ADVTSE-KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 DVT + + L + VD+ +N AGI +R + +N Sbjct: 62 YDVTVPVAESKKLLKKIFDQLKTVDILINGAGILDDH--------------QIERTIAIN 107 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 G N + + +GG G+I N SV F YSASK +V T Sbjct: 108 FTGLVNTTTAILDFWDKR---KGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNS 164 Query: 182 IARDLAP-IGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEY--AHLVQ 238 +A+ LAP G+ +I PG+ TPL+ + + S +E + V+ Sbjct: 165 LAK-LAPITGVTAYSINPGITRTPLVHTFNSWLDVEPRVAELLLSHPTQTSEQCGQNFVK 223 Query: 239 AIIENPFLNGEVIRLDGA 256 AI N NG + +LD Sbjct: 224 AIEANK--NGAIWKLDLG 239 >3KZV-A nrPDB Length = 254 Score = 128 bits (321), Expect = 4e-30, Method: Composition-based stats. Identities = 37/207 (17%), Positives = 86/207 (41%), Gaps = 16/207 (7%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG--EAQAKKLGNNCVFAPADVT 66 G V ++TG + G+G + + L V+ + S + +K G+ + D+T Sbjct: 1 MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDIT 60 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + ++ + A G++D V AG+ + N + ++++ D+N Sbjct: 61 EDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVN-----EIDVNAWKKLYDINFFSIV 115 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 +++ + E+ + G ++ +S A AY +SK + + +A + Sbjct: 116 SLVGIALPELKKT-------NGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE- 167 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKV 213 ++ + +APG+ T + ++ E V Sbjct: 168 -ERQVKAIAVAPGIVDTDMQVNIRENV 193 >3E9N-A nrPDB Length = 245 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 52/248 (20%), Positives = 98/248 (39%), Gaps = 23/248 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 S+K +AV+TG G+G+ + L L A A+ G +D+ Sbjct: 2 SLKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEG--VEPIESDIV 58 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E + + K VD V+ A +A + + ++ ++ LD+N++ Sbjct: 59 KEVLEEGGVDKLKN-LDHVDTLVHAAAVARDTTI------EAGSVAEWHAHLDLNVIVPA 111 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + R + + G +I S A G Y+ASK + G+ ++ Sbjct: 112 ELSRQLLPALRAA-------SGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEE 164 Query: 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFL 246 A GIRV T++PG TP+L L + ++ +P E A+ ++ +I+ Sbjct: 165 ANNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEI-----YIEPKEIANAIRFVIDAGET 219 Query: 247 NGEVIRLD 254 ++ +D Sbjct: 220 T-QITNVD 226 >2HRB-A nrPDB Length = 274 Score = 121 bits (304), Expect = 3e-28, Method: Composition-based stats. Identities = 49/245 (20%), Positives = 80/245 (32%), Gaps = 65/245 (26%) Query: 11 LVAVITGGASGLGLATAERLVGQ-GASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVT 66 VA++TG G+GLA A L Q VL + G+A ++L G + F D+ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 62 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + ++ + ++G ++V VN A +A S + + L N T Sbjct: 63 DLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKA------EMTLKTNFFATR 116 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTAS------------------------------- 155 N+ + M G ++N +S Sbjct: 117 NMCNELLPIMK--------PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDL 168 Query: 156 -----------VAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI----GIRVMTIAPGL 200 V EG + Y SK G+ ++ +AR L I V PG Sbjct: 169 MKKFVEDTKNEVHEREGWPN-SPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGP 227 Query: 201 FGTPL 205 T + Sbjct: 228 VKTDM 232 >1MG5-A nrPDB Length = 255 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 53/213 (24%), Positives = 82/213 (38%), Gaps = 24/213 (11%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGAS-AVLLDL---PNSGGEAQAKKLGNNCVFAP 62 ++ + G G+GL T++ L+ + V+LD P + E +A F P Sbjct: 3 TLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYP 62 Query: 63 ADVTSE-KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 DVT + L + VDV +N AGI +R + VN Sbjct: 63 YDVTVPIAETTKLLKTIFAQLKTVDVLINGAGILDDH--------------QIERTIAVN 108 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 G N + + +GG G+I N SV F YS +K +V T Sbjct: 109 YTGLVNTTTAILDFWDKR---KGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSS 165 Query: 182 IARDLAP-IGIRVMTIAPGLFGTPLLTSLPEKV 213 +A+ LAP G+ T+ PG+ T L+ + Sbjct: 166 LAK-LAPITGVTAYTVNPGITRTTLVHKFNSWL 197 >3O26-A nrPDB Length = 311 Score = 117 bits (294), Expect = 4e-27, Method: Composition-based stats. Identities = 58/285 (20%), Positives = 87/285 (30%), Gaps = 80/285 (28%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----NCVFAPAD 64 K AV+TGG G+G ++L G VL + G +KL N N VF D Sbjct: 11 KRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLD 70 Query: 65 VTSE-KDVQTALALAKGKFGRVDVAVNCAGIAVAS-KTYNLKKGQTHTLEDFQRV----- 117 VT + + K FG++D+ VN AG+A S K + ED + + Sbjct: 71 VTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYE 130 Query: 118 ------------------LDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA- 158 L +N G +V ++ + Q I+N +S Sbjct: 131 KPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLL------QLSDSPRIVNVSSSTGS 184 Query: 159 -----------------------------------------FEGQVGQ-AAYSASKGGIV 176 G AAY+ SK + Sbjct: 185 LKYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLN 244 Query: 177 GMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQV 221 T +A + V + PGL T + + A V Sbjct: 245 AYTRVLANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHV 287 >3OIG-A nrPDB Length = 266 Score = 117 bits (293), Expect = 6e-27, Method: Composition-based stats. Identities = 46/264 (17%), Positives = 92/264 (34%), Gaps = 21/264 (7%) Query: 7 SVKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG----NNCVF 60 S++G V+ G A + A L GA + ++ + G N+ + Sbjct: 4 SLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSII 63 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 P DVT++ +++T A K + G + +C IA A+K + + + F ++ Sbjct: 64 LPCDVTNDAEIETCFASIKEQVGVIHGIAHC--IAFANKEELVGEYLNTNRDGFLLAHNI 121 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 + V++ M + G I+ + +K + Sbjct: 122 SSYSLTAVVKAARPMMTE--------GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVK 173 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQ 238 +A DL IRV +I+ G T + + + + + P R P E Sbjct: 174 YLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPL-RRTTTPEEVGDTAA 232 Query: 239 AIIEN--PFLNGEVIRLDGAIRMQ 260 + + + GE + +D + Sbjct: 233 FLFSDMSRGITGENLHVDSGFHIT 256 >5L51-A nrPDB Length = 324 Score = 114 bits (285), Expect = 4e-26, Method: Composition-based stats. Identities = 49/280 (17%), Positives = 83/280 (29%), Gaps = 87/280 (31%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG----EAQAKKLGNN----CVFAP 62 AV+TG G+G ++L +G + +L G E K+LG+ V Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDF-------- 114 DV V + K KFG +D+ VN AG+ + + +F Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSGAA 135 Query: 115 --------------------QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTA 154 + ++ N G+ V + + Q++ I+N + Sbjct: 136 KTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSP------RIVNVS 189 Query: 155 SV----------------AAFEGQ---------------------------VGQAAYSAS 171 S ++ EG +AY S Sbjct: 190 STLSSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVS 249 Query: 172 KGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE 211 K + T IA+ R+ + PG T L + Sbjct: 250 KAALNAYTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQ 287 >4M89-A nrPDB Length = 261 Score = 114 bits (285), Expect = 5e-26, Method: Composition-based stats. Identities = 45/261 (17%), Positives = 90/261 (34%), Gaps = 19/261 (7%) Query: 8 VKGLVAVITG--GASGLGLATAERLVGQGASAV---LLDLPNSGGEAQAKKLGNNCVFAP 62 ++G +ITG + A+ QGA ++D A +L + VF Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVF-R 62 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV S+ ++ A + +D V+ G A + + + + E F +++ Sbjct: 63 CDVASDDEINQVFADLGKHWDGLDGLVHSIGFA-PKEALSGDFLDSISREAFNTAHEISA 121 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + M G+ I+ + + A +K + Sbjct: 122 YSLPALAKAARPMM-------RGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFT 174 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 A L GIR I+ G T + + + K+ +A+ P R E + + Sbjct: 175 AACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPL-RRNVTIEEVGNTAAFL 233 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + + + GE+ +DG + Sbjct: 234 LSDLSSGITGEITYVDGGYSI 254 >5PGZ-A nrPDB Length = 276 Score = 111 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 42/204 (20%), Positives = 73/204 (35%), Gaps = 21/204 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAK---KLG-NNCVFAPA 63 ++G ++TG + G+G A L GA VL G + +LG + + Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 + + + A G +D+ + I S + + +RV++VN + Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDMLILNH-ITQTSLSLFHDDIHSV-----RRVMEVNFL 129 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + Q+ G I +S+A Q A YSASK + G I Sbjct: 130 SYVVMSTAALPMLKQS-------NGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIR 182 Query: 184 RDLAPIGIRVM---TIAPGLFGTP 204 +L + V + GL T Sbjct: 183 TELYITKVNVSITLCVL-GLIDTE 205 >5YCX-A nrPDB Length = 266 Score = 111 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 45/267 (16%), Positives = 87/267 (32%), Gaps = 23/267 (8%) Query: 4 ACRSVKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL-----GN 56 + ++G V+ G A + A L GA + E ++L G Sbjct: 2 SMELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFT-YAGERLERNVRELADTLEGQ 60 Query: 57 NCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQR 116 + P DVT+++++ K + G + +C IA A++ + + + F Sbjct: 61 ESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHC--IAFANRDDLKGEFVDTSRDGFLL 118 Query: 117 VLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 +++ V R M + G I+ + +K + Sbjct: 119 AQNISAFSLTAVAREAKKVMTE--------GGNILTLTYLGGERVVKNYNVMGVAKASLE 170 Query: 177 GMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYA 234 +A DL GIRV I+ G T + + + + + P R E Sbjct: 171 ASVKYLANDLGQHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPL-RRTTTQEEVG 229 Query: 235 HLVQAIIEN--PFLNGEVIRLDGAIRM 259 + + + GE I +D + Sbjct: 230 DTAVFLFSDLARGVTGENIHVDSGYHI 256 >1N5D-A nrPDB Length = 288 Score = 111 bits (278), Expect = 3e-25, Method: Composition-based stats. Identities = 49/244 (20%), Positives = 80/244 (32%), Gaps = 63/244 (25%) Query: 11 LVAVITGGASGLGLATAERLVGQGA-SAVLLDLPNSGGEAQAKKL---GNNCVFAPADVT 66 VA++TG G+G A L Q A VL + G+A K+L G + F D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + ++ + ++G +DV VN A IA N + + N MGT Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAFQ--LDNPTPFHIQA----ELTMKTNFMGTR 118 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAA------------------------FEGQ 162 NV + + G ++N +S G Sbjct: 119 NVCTELLPLIKPQ--------GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGL 170 Query: 163 VGQ-----------------AAYSASKGGIVGMTLPIARDL----APIGIRVMTIAPGLF 201 + + + Y +K G+ ++ AR L A I + PG Sbjct: 171 MNKFVEDTKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWV 230 Query: 202 GTPL 205 T + Sbjct: 231 RTDM 234 >3DWF-A nrPDB Length = 276 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 71/204 (34%), Gaps = 21/204 (10%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAK---KLG-NNCVFAPA 63 ++G ++TG + G+G A L GA V+ + +LG + + Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 + + +A A G +D+ + YN +++ ++ ++VN Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNH------VLYNRLTFFHGEIDNVRKSMEVNFH 122 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + Q++ G I +SVA A YSASK + G + Sbjct: 123 SFVVLSVAAMPMLMQSQ-------GSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLR 175 Query: 184 RDLAPIGIRVM---TIAPGLFGTP 204 + + V I GL T Sbjct: 176 SEFLVNKVNVSITLCIL-GLIDTE 198 >3U9L-A nrPDB Length = 324 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 98/241 (40%), Gaps = 23/241 (9%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAV-----LLDLPNSGGEAQAKKLGNNCV---FAP 62 + +ITG +SG G TAE L G G ++ S EA A +N V Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLE 65 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV S+ V A+ G+ GR+DV ++ AG V + T E F + D+N+ Sbjct: 66 LDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMV------FGPAEAFTPEQFAELYDINV 119 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQ-AAYSASKGGIVGMTLP 181 + T V R M + + G++I +S ++ G A Y A+K + + + Sbjct: 120 LSTQRVNRAALPHMRRQ------KHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQ 173 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPS--RLGDPAEYAHLVQA 239 AR+L+ GI I PG F + V + A Q + + G E A Sbjct: 174 YARELSRWGIETSIIVPGAFTSGTNHFAHSGVPDDHARQAEYEAGPNAGLGEEIKKAFAA 233 Query: 240 I 240 I Sbjct: 234 I 234 >5KOI-A nrPDB Length = 293 Score = 110 bits (276), Expect = 6e-25, Method: Composition-based stats. Identities = 50/261 (19%), Positives = 94/261 (36%), Gaps = 20/261 (7%) Query: 8 VKGLVAVITGGASGLGLA--TAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAP 62 ++G +I G A+ LA A++L QGA ++ G+ A+++G++ V P Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFV-LP 84 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV V + K+G +D V+ G + + T E+F R + ++ Sbjct: 85 CDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFS-DKTELKGRYADVTTRENFSRTMVISA 143 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 V + M G I+ + +K + M + Sbjct: 144 YSFTEVAQRAEKLMK--------DGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYL 195 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 A D P GIRV I+ G T + + + ++ P R D + + Sbjct: 196 AADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPL-RRTVDIDDVGKSAVYL 254 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + + + GE+ +D + Sbjct: 255 LSDLSSGVTGEIHFVDSGYNI 275 >4NR0-A nrPDB Length = 273 Score = 109 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 47/267 (17%), Positives = 89/267 (33%), Gaps = 22/267 (8%) Query: 8 VKGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNN-CVFA 61 + G A+I G AS + A + +GA + E A G+ + Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 Query: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 P DV + ++ A + +D+ V+ G A + T E F+ D++ Sbjct: 64 PCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFA-PGDQLDGDFTAVTTREGFRIAHDIS 122 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + + M G+ G ++ + + A +K + Sbjct: 123 AYSFIALAKAGREMMK-------GRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRY 175 Query: 182 IARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQA 239 +A L G RV ++ G T + + K+ Q P R E + Sbjct: 176 LAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPL-RRNVTIEEVGNAGAF 234 Query: 240 IIEN--PFLNGEVIRLDGAI---RMQP 261 + + ++GE++ +DG M P Sbjct: 235 LCSDLASGISGEILYVDGGFNTTAMGP 261 >3BHI-A nrPDB Length = 276 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 47/244 (19%), Positives = 82/244 (33%), Gaps = 65/244 (26%) Query: 12 VAVITGGASGLGLATAERLVG--QGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVT 66 VA++TGG G+GLA L G VL + G+A ++L G + F D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSG-DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 64 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + ++ + ++G +DV VN AGIA K + + + N GT Sbjct: 65 DLQSIRALRDFLRKEYGGLDVLVNNAGIAF--KVADPTPFHIQA----EVTMKTNFFGTR 118 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------------------------ 162 +V + + G ++N +S+ + Sbjct: 119 DVCTELLPLIKPQ--------GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGL 170 Query: 163 -----------------VGQAAYSASKGGIVGMTLPIARDLAPI----GIRVMTIAPGLF 201 +AY +K G+ ++ AR L+ I + PG Sbjct: 171 MNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWV 230 Query: 202 GTPL 205 T + Sbjct: 231 RTDM 234 >5I9N-A nrPDB Length = 276 Score = 107 bits (268), Expect = 4e-24, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 86/259 (33%), Gaps = 20/259 (7%) Query: 8 VKGLVAVITG--GASGLGLATAERLVGQGASAV---LLDLPNSGGEAQAKKLGNNCVFAP 62 + G ++TG + A+ +GA + D A + G+ VF P Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVF-P 62 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV + + A K + +D V+ G A T E+F+ D++ Sbjct: 63 CDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAG-DFLDGLTRENFRIAHDISA 121 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + + + ++ + + A +K + + Sbjct: 122 YSFPALAKAALPMLSDD--------ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYL 173 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 A L G+RV I+ G T + + K+ +F+ S P R + + + Sbjct: 174 AVSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPL-KRNVTIEQVGNAGAFL 232 Query: 241 IEN--PFLNGEVIRLDGAI 257 + + + EV+ +D Sbjct: 233 LSDLASGVTAEVMHVDSGF 251 >4ZJU-A nrPDB Length = 275 Score = 107 bits (267), Expect = 6e-24, Method: Composition-based stats. Identities = 45/259 (17%), Positives = 86/259 (33%), Gaps = 19/259 (7%) Query: 8 VKGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNNCVFAP 62 + G +I G AS + A+ L +GA + A++ G+ VF P Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVF-P 72 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV + ++ A A + VD V+ G A + T + + F+ D++ Sbjct: 73 CDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFA-PAHTLDGDFTDVTDRDGFKIAHDISA 131 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + R + ++G ++ + +K + + Sbjct: 132 YSFVAMARAAKPLLQ-------ARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYL 184 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 A L GIRV I+ G T + + K+ + P R E + + Sbjct: 185 ASSLGVDGIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPL-KRNVTIEEVGNAALFL 243 Query: 241 IE--NPFLNGEVIRLDGAI 257 + GE++ +D Sbjct: 244 CSPWASGITGEILYVDAGF 262 >5CFZ-A nrPDB Length = 305 Score = 106 bits (266), Expect = 7e-24, Method: Composition-based stats. Identities = 44/261 (16%), Positives = 90/261 (34%), Gaps = 20/261 (7%) Query: 8 VKGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNNCVFAP 62 + G ++TG AS + A+ + +GA + E A +LG++ V Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQ 105 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV + + T A + + D V+ G A + T E F+ D++ Sbjct: 106 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA-PGDQLDGDYVNAVTREGFKIAHDISS 164 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + M ++ + + A +K + + Sbjct: 165 YSFVAMAKAC-RSMLNPGSA-------LLTLSYLGAERAIPNYNVMGLAKASLEANVRYM 216 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 A + P G+RV I+ G T + + + K+ + P R + + + Sbjct: 217 ANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPI-RRTVTIEDVGNSAAFL 275 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + ++GEV+ +DG + Sbjct: 276 CSDLSAGISGEVVHVDGGFSI 296 >1SNY-A nrPDB Length = 267 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 42/207 (20%), Positives = 69/207 (33%), Gaps = 20/207 (9%) Query: 14 VITGGASGLGLATAERLV---GQGASAVLLDLPNSGGEAQAKKLGN--NCVFAPADVTSE 68 +ITG GLGL + L+ + N N D+ + Sbjct: 25 LITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRNF 84 Query: 69 KDVQTALALA--KGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 +A K ++V N AGIA S + ++ L N + Sbjct: 85 DAYDKLVADIEGVTKDQGLNVLFNNAGIAPKS-----ARITAVRSQELLDTLQTNTVVPI 139 Query: 127 NVIRLVAGEMGQNEPD-----QGGQRGVIINTASVAA-FEGQ--VGQAAYSASKGGIVGM 178 + + + + G R IIN +S+ +G G AY SK + Sbjct: 140 MLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAA 199 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPL 205 T ++ DL P I +++ PG T + Sbjct: 200 TKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >3GRK-A nrPDB Length = 293 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 48/268 (17%), Positives = 85/268 (31%), Gaps = 21/268 (7%) Query: 1 MAAACRSVKGLVAVITGGA--SGLGLATAERLVGQGASAVLL---DLPNSGGEAQAKKLG 55 M A ++G +I G A + A+ GA D E A++LG Sbjct: 22 MTAQSGLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELG 81 Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 V DV + + K+G++D V+ I + K + + +F Sbjct: 82 A-FVAGHCDVADAASIDAVFETLEKKWGKLDFLVH--AIGFSDKDELTGRYIDTSEANFT 138 Query: 116 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 + +++ V R M G I+ A + +K + Sbjct: 139 NTMLISVYSLTAVSRRAEKLM--------ADGGSILTLTYYGAEKVMPNYNVMGVAKAAL 190 Query: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEY 233 +A DL P IRV I+ G T + + + + + P R E Sbjct: 191 EASVKYLAVDLGPQNIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPL-RRTVTIDEV 249 Query: 234 AHLVQAIIEN--PFLNGEVIRLDGAIRM 259 + + + + GEV D + Sbjct: 250 GDVGLYFLSDLSRSVTGEVHHADSGYHV 277 >4JQC-A nrPDB Length = 282 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 44/261 (16%), Positives = 90/261 (34%), Gaps = 20/261 (7%) Query: 8 VKGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNNCVFAP 62 + G ++TG AS + A+ + +GA + E A +LG++ V Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQ 82 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV + + T A + + D V+ G A + T E F+ D++ Sbjct: 83 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA-PGDQLDGDYVNAVTREGFKIAHDISS 141 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + M ++ + + A +K + + Sbjct: 142 YSFVAMAKAC-RSMLNPGSA-------LLTLSYLGAERAIPNYNVMGLAKASLEANVRYM 193 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYAHLVQAI 240 A + P G+RV I+ G T + + + K+ + P R + + + Sbjct: 194 ANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPI-RRTVTIEDVGNSAAFL 252 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + ++GEV+ +DG + Sbjct: 253 CSDLSAGISGEVVHVDGGFSI 273 >3UCF-A nrPDB Length = 223 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 50/248 (20%), Positives = 88/248 (35%), Gaps = 39/248 (15%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 V V+ GG SG+G A++L + + V + +G D++ EK V Sbjct: 8 VYVVLGGTSGIGAELAKQLESE-HTIVHVASRQTGL----------------DISDEKSV 50 Query: 72 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 G D + AG + + + D G + Sbjct: 51 YHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQA-----KYAFDTKFWGAVLAAKH 101 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 A + Q G I T+ + + + +A I T +A++LAP I Sbjct: 102 GARYLK--------QGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--I 151 Query: 192 RVMTIAPGLFGTPLLTSLPEKVCNFLASQVP---FPSRLGDPAEYAHLVQAIIENPFLNG 248 RV I+PGL T + + + + ++G+ ++ A I+N ++ G Sbjct: 152 RVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAYLFAIQNSYMTG 211 Query: 249 EVIRLDGA 256 VI +DG Sbjct: 212 TVIDVDGG 219 >5TF4-A nrPDB Length = 274 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 42/268 (15%), Positives = 86/268 (32%), Gaps = 21/268 (7%) Query: 1 MAAACRSVKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLG 55 MA + G +I G A + A+ GA + E A+++ Sbjct: 3 MAKGNGLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVK 62 Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 V DV+ + + K+G++D V+ G + + + + +F Sbjct: 63 G-FVCGHCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELS--GRYVDISESNFM 119 Query: 116 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 +++++ + + M G I+ A + +K + Sbjct: 120 MTMNISVYSLTALTKRAEKLM--------SDGGSILTLTYYGAEKVVPNYNVMGVAKAAL 171 Query: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEY 233 +A DL P IRV I+ G T + + + + + P R E Sbjct: 172 EASVKYLAVDLGPKHIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPL-RRTVTIEEV 230 Query: 234 AHLVQAIIEN--PFLNGEVIRLDGAIRM 259 ++ + + GEV +D + Sbjct: 231 GDSALYLLSDLSRSVTGEVHHVDSGYNI 258 >1FJH-A nrPDB Length = 257 Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 63/285 (22%), Positives = 108/285 (37%), Gaps = 68/285 (23%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 + VI+G A+G+G AT + L G V +D+ ++ AD+++ + Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE--------------VIADLSTAEGR 48 Query: 72 QTALALAKGKFG-RVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 + A+A K +D V CAG+ +K V+ VN G ++ Sbjct: 49 KQAIADVLAKCSKGMDGLVLCAGLGPQTKVLG-------------NVVSVNYFGATELMD 95 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFE----------------------------GQ 162 + + G + + +SVA+ Q Sbjct: 96 AFLPALKK------GHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQ 149 Query: 163 VGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTS--LPEKVCNFLASQ 220 G AY+ SK + A G+R+ TIAPG TPLL + + +A Sbjct: 150 GGNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKF 209 Query: 221 VPFPSRLGDPAEYAHLVQAIIE--NPFLNGEVIRLDGAIR--MQP 261 VP R +P+E A ++ ++ +++G I +DG I M+P Sbjct: 210 VPPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGIDAVMRP 254 >3K2E-A nrPDB Length = 296 Score = 101 bits (252), Expect = 3e-22, Method: Composition-based stats. Identities = 45/269 (16%), Positives = 86/269 (31%), Gaps = 22/269 (8%) Query: 2 AAACRS---VKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPN---SGGEAQAKK 53 + R+ ++G VI G A L A+ + QGA L L + A+ Sbjct: 19 PGSMRTGMLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAES 78 Query: 54 LGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED 113 LG + P DV+ + V + ++G +D V+ +A + K + +L + Sbjct: 79 LGVK-LTVPCDVSDAESVDNMFKVLAEEWGSLDFVVH--AVAFSDKNELKGRYVDTSLGN 135 Query: 114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173 F + ++ + M G I+ + A + K Sbjct: 136 FLTSMHISCYSFTYIASKAEPLMT--------NGGSILTLSYYGAEKVVPHYNVMGVCKA 187 Query: 174 GIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE-KVCNFLASQVPFPSRLGDPAE 232 + +A DL IRV I+ G T + + + R + Sbjct: 188 ALEASVKYLAVDLGKQQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDD 247 Query: 233 YAHLVQAIIEN--PFLNGEVIRLDGAIRM 259 ++ + GE + +D + Sbjct: 248 VGGAALYLLSDLGRGTTGETVHVDCGYHV 276 >4ALL-A nrPDB Length = 277 Score = 100 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 47/262 (17%), Positives = 79/262 (30%), Gaps = 21/262 (8%) Query: 7 SVKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----NCVF 60 +++ VI G A + A+ L GA V + K L Sbjct: 24 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHL 83 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 DV S+++V G +D + IA A+ + + E F D+ Sbjct: 84 YQIDVQSDEEVINGFEQIGKDVGNIDGVYHS--IAFANMEDLRGRFSETSREGFLLAQDI 141 Query: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 + V M + G I+ T + +K + Sbjct: 142 SSYSLTIVAHEAKKLMPE--------GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVK 193 Query: 181 PIARDLAPIGIRVMTIAPGLFGTPLLTSLP--EKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 +A DL P IRV I+ G T + + + + P R D E Sbjct: 194 YLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPL-KRNVDQVEVGKTAA 252 Query: 239 AIIEN--PFLNGEVIRLDGAIR 258 ++ + + GE I +D Sbjct: 253 YLLSDLSSGVTGENIHVDSGFH 274 >5LCX-A nrPDB Length = 316 Score = 99 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 46/277 (16%), Positives = 74/277 (26%), Gaps = 89/277 (32%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL-------GNNCVFAPA 63 A++TG G+G +L +G +L G +KL N VF Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD---- 119 DVT V K KFG++D+ VN AG++ ++ + DF+ + Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAG 127 Query: 120 ---------------------------VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIIN 152 N G + + + + + I+N Sbjct: 128 AKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSP------RIVN 181 Query: 153 TASVA------------AFEG-------------------------------QVGQAAYS 169 +S G AA Sbjct: 182 VSSSFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAER 241 Query: 170 ASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLL 206 SK + T A+ R+ I PG T + Sbjct: 242 VSKAALNAYTKIAAKKYPSF--RINAICPGYAKTDIT 276 >4J3F-A nrPDB Length = 280 Score = 98.0 bits (243), Expect = 4e-21, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 83/259 (32%), Gaps = 18/259 (6%) Query: 8 VKGLVAVITG--GASGLGLATAERLVGQGASAVLLDLPN--SGGEAQAKKLGNNCVFAPA 63 + G +ITG + A+ + +GA + E + N P Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEF-NPAAVLPC 82 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV S+++++ + +D V+ A T E F D++ Sbjct: 83 DVISDQEIKDLFVELGKVWDGLDAIVHSIAFA-PRDQLEGNFIDCVTREGFSIAHDISAY 141 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + M + ++ + A + +K + A Sbjct: 142 SFAALAKEGRSMMKN-------RNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTA 194 Query: 184 RDLAPIGIRVMTIAPGLFGTPLLTSLP--EKVCNFLASQVPFPSRLGDPAEYAHLVQAII 241 L GI+V ++ G T + + +K+ ++ A P + D E + V + Sbjct: 195 LALGEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNV-DIMEVGNTVAFLC 253 Query: 242 EN--PFLNGEVIRLDGAIR 258 + + GEV+ +D Sbjct: 254 SDMATGITGEVVHVDAGYH 272 >4HWK-A nrPDB Length = 288 Score = 93.4 bits (231), Expect = 8e-20, Method: Composition-based stats. Identities = 45/220 (20%), Positives = 80/220 (36%), Gaps = 27/220 (12%) Query: 5 CRSVKG----LVAVITGGASGLGL---ATAERLVGQGASAVLLDLPNSGGEAQAKKLGN- 56 R+++G V ++TG + G G L+ G+ VL + +LG Sbjct: 25 VRTMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAE 84 Query: 57 ----NCVFAPADVTSEKDVQTALALAKG-----KFGRVDVAVNCAGIAVASKTYNLKKGQ 107 V PAD+ +E +Q L + R+ + +N AG + Sbjct: 85 RSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSD 143 Query: 108 THTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA 167 + + ++ +NL + V PD G ++N +S+ A + G A Sbjct: 144 STQVNNY---WALNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGWAL 196 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLT 207 Y A K + +A + +RV+ APG T + Sbjct: 197 YCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQ 234 >4Z3K-A nrPDB Length = 275 Score = 93.4 bits (231), Expect = 9e-20, Method: Composition-based stats. Identities = 43/209 (20%), Positives = 75/209 (35%), Gaps = 23/209 (11%) Query: 12 VAVITGGASGLGL---ATAERLVGQGASAVLLDLPNSGGEAQAKKLGN-----NCVFAPA 63 V ++TG + G G L+ G+ VL + +LG V PA Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 64 DVTSEKDVQTALALAKG-----KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 D+ +E +Q L + R+ + +N AG + + + ++ Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNY---W 138 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 +NL + V PD G ++N +S+ A + G A Y A K + Sbjct: 139 ALNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 194 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLT 207 +A + +RV+ APG T + Sbjct: 195 FQVLALE--EPNVRVLNYAPGPLDTDMQQ 221 >4NK4-A nrPDB Length = 301 Score = 91.5 bits (226), Expect = 4e-19, Method: Composition-based stats. Identities = 43/267 (16%), Positives = 87/267 (32%), Gaps = 19/267 (7%) Query: 1 MAAACRSVKGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLPNSGGEAQ--AKKLGN 56 M +KG +I G A+ + A+ L GA S G+ + Sbjct: 32 MGRMINILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVD 91 Query: 57 NCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQR 116 + P +V + K ++ +D V+ IA + K + ++F + Sbjct: 92 SDFMIPCNVEDPSSMDLLFERIKERWETLDFVVHS--IAFSDKNELRGPYYNTSRDNFIQ 149 Query: 117 VLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 + V+ ++R A M G +I + A + +K + Sbjct: 150 TMLVSCFSFTEIVRRAAQLMP--------HGGAMITLTYGGSMRVVPNYNAMAPAKSALE 201 Query: 177 GMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEYA 234 T +A D + IR+ I+ G T S+ + + P R + Sbjct: 202 SSTKYLACDYGGMNIRINAISAGPVRTLAGASISNGRDIAAWSKENSPL-KRTVSLEDIG 260 Query: 235 HLVQAIIE--NPFLNGEVIRLDGAIRM 259 + ++ + + GE+ +D + Sbjct: 261 NSALYLLSYLSNGVTGEIHYVDCGYNI 287 >2PD3-A nrPDB Length = 275 Score = 88.8 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 39/261 (14%), Positives = 87/261 (33%), Gaps = 21/261 (8%) Query: 8 VKGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAP 62 +KG +I G A + A+ QGA+ L S + A++L + V+ Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVY-E 62 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 DV+ E+ ++ K G +D V+ A + F +++++ Sbjct: 63 LDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALE--GSLLETSKSAFNTAMEISV 120 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + + ++ + + + + +K + + Sbjct: 121 YSLIELTNTLKPLLN--------NGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYL 172 Query: 183 ARDLAPIGIRVMTIAPGLFGTPLLTSLPE--KVCNFLASQVPFPSRLGDPAEY--AHLVQ 238 A DL IRV ++ G T + + + + + P + E A + Sbjct: 173 AVDLGKHHIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSL-EEVGNAGMYL 231 Query: 239 AIIENPFLNGEVIRLDGAIRM 259 + ++GEV +D + Sbjct: 232 LSSLSSGVSGEVHFVDAGYHV 252 >4Q9N-A nrPDB Length = 298 Score = 88.0 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 51/300 (17%), Positives = 102/300 (34%), Gaps = 57/300 (19%) Query: 7 SVKGLVAVITGGAS--GLGLATAERLVGQGASAVL---------------LDLPNSGGEA 49 + G +A I G G G A+ L GA+ ++ L N+ E Sbjct: 5 DLTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASREL 64 Query: 50 QAKKLGNNCVFAPADVT--SEKD------------------VQTALALAKGKFGRVDVAV 89 +L P D + + +D V + K FG +D+ V Sbjct: 65 SNGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILV 124 Query: 90 NCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGV 149 + ++A+ K + + + L + +++ M + G Sbjct: 125 H----SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM-----NAGASTIS 175 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-GIRVMTIAPGLFGTPLLTS 208 + AS+ A G G A+K + T +A + G+RV TI+ G + + Sbjct: 176 LTYLASMRAVPGYGGGMN--AAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKA 233 Query: 209 LP--EKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NPFLNGEVIRLDGA---IRMQP 261 + E++ ++ P PS + + + ++ + GE + +D + + P Sbjct: 234 IGFIERMVDYYQDWAPLPSPM-EAEQVGAAAAFLVSPLASAITGETLYVDHGANVMGIGP 292 >1OAA-A nrPDB Length = 259 Score = 87.6 bits (216), Expect = 5e-18, Method: Composition-based stats. Identities = 42/217 (19%), Positives = 76/217 (35%), Gaps = 23/217 (10%) Query: 12 VAVITGGASGLGLATAERLVGQ---GASAVLLDLPNSGGEAQAKKLGN-----NCVFAPA 63 V V+TG + G G A A +L G+ ++ S ++LG V A A Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 64 DVTSEKDVQTALALAKG-----KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 118 D+ +E VQ L+ + R+ + +N A L + ++ Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNY---W 123 Query: 119 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 +NL + + G ++N +S+ A + G Y A K + Sbjct: 124 ALNLTSMLCLTSGTLNAFQDSP----GLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 179 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCN 215 +A + +RV++ APG + E + Sbjct: 180 YQVLAAE--EPSVRVLSYAPGPLDNDMQQLARETSKD 214 >5TQV-A nrPDB Length = 233 Score = 87.6 bits (216), Expect = 5e-18, Method: Composition-based stats. Identities = 35/195 (17%), Positives = 70/195 (35%), Gaps = 15/195 (7%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 +I G + GLG + G + + ++ A + LG + D+T + Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAAL-RALGAHAHAL--DITQPEQ 66 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 + G+ R+DVAV +G+ + +T +DF V+ N+ G ++ Sbjct: 67 IAALGWKLDGE--RLDVAVVVSGVYGP----RTEGVETIASDDFDTVMHTNVRGPMQLLP 120 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 ++ + S++ G G Y ASK + + + L Sbjct: 121 ILLPLVEDARGVLAVVSSR---MGSISEATGTTGW-LYRASKAALNDVLRIAS--LQTRH 174 Query: 191 IRVMTIAPGLFGTPL 205 +++ PG T + Sbjct: 175 AACISLHPGWVRTDM 189 >5WQO-A nrPDB Length = 234 Score = 86.8 bits (214), Expect = 9e-18, Method: Composition-based stats. Identities = 33/199 (16%), Positives = 68/199 (34%), Gaps = 20/199 (10%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNNCVFAPADVTSEK 69 +I G + G+GL A+ + +GA + G +A A++ G D+ Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 Query: 70 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVI 129 + + + R+D + AGI + + E ++ N + + Sbjct: 69 CAERIGEMLGER--RIDRLIVNAGIYGPQQ----QDVAEIDAEQTAQLFLTNAIAPLRLA 122 Query: 130 RLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA---AYSASKGGIVGMTLPIARDL 186 R + + + GV+ +S A A Y ASK + + + Sbjct: 123 RAL--------SGRVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEF 174 Query: 187 APIGIRVMTIAPGLFGTPL 205 + ++ + PG T + Sbjct: 175 EELPFSLLLLHPGWVRTEM 193 >2NTV-A nrPDB Length = 268 Score = 86.1 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 46/276 (16%), Positives = 93/276 (33%), Gaps = 36/276 (13%) Query: 8 VKGLVAVITG--GASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKLGNNCVFAPAD 64 ++G +++G S + A+ GA VL + A +L + D Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIELD 63 Query: 65 VTSEKDVQTALALAKGKFG---RVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 V +E+ + T + G ++D V+ G + ED + + ++ Sbjct: 64 VQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFM-PQTGMGTNQFFDAPYEDVSKGIHIS 122 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAY---SASKGGIVGM 178 ++ + + M G I+ F+ AY + +K + + Sbjct: 123 TYSYASLAKALLLIMN--------SGGSIVGMD----FDPTRAMPAYNWMTVAKSALESV 170 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSL------------PEKVCNFLASQVPFPSR 226 +AR+ G+R +A G T ++++ + + + P Sbjct: 171 NRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWN 230 Query: 227 LGDPAEYAHLVQAIIEN--PFLNGEVIRLDGAIRMQ 260 + DP A V A++ P G +I DG Q Sbjct: 231 MKDPTPVAKTVCALLSEWLPATTGSIIYADGGASTQ 266 >4OYR-A nrPDB Length = 289 Score = 83.0 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 44/276 (15%), Positives = 88/276 (31%), Gaps = 36/276 (13%) Query: 8 VKGLVAVITG--GASGLGLATAERLVGQGASAVLLDLPN-SGGEAQAKKLGNNCVFAPAD 64 + G +++G S + A QGA VL + +L D Sbjct: 25 LDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELD 84 Query: 65 VTSEKDVQTALALAKGKFG---RVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 V +E+ + + G ++D V+ G + D + + ++ Sbjct: 85 VQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFM-PQTGMGINPFFDAPYADVSKGIHIS 143 Query: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAY---SASKGGIVGM 178 ++ + + M G I+ F+ AY + +K + + Sbjct: 144 AYSYASMAKALLPIMN--------PGGSIVGMD----FDPSRAMPAYNWMTVAKSALESV 191 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGT-PLLTSLPEKVCNFLASQV-----------PFPSR 226 +AR+ G+R +A G T + + + +Q+ P Sbjct: 192 NRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWN 251 Query: 227 LGDPAEYAHLVQAIIEN--PFLNGEVIRLDGAIRMQ 260 + D A V A++ + P G++I DG Q Sbjct: 252 MKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQ 287 >1ENP-A nrPDB Length = 312 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 54/293 (18%), Positives = 98/293 (33%), Gaps = 54/293 (18%) Query: 7 SVKGLVAVITGGAS--GLGLATAERLVGQGASAVLLD----------------------L 42 ++G A I G A G G A A+ L GA ++ L Sbjct: 15 DLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVL 74 Query: 43 PNSGGEAQAKKLGNNCVF-----APADV--------TSEKDVQTALALAKGKFGRVDVAV 89 P+ K + VF P DV +S VQ A + FG +D+ V Sbjct: 75 PDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILV 134 Query: 90 NCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGV 149 + ++A+ K + + + + + +++ M + GG Sbjct: 135 H----SLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM-----NPGGASIS 185 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-GIRVMTIAPGLFGTPLLTS 208 + AS G G S++K + T +A + IRV TI+ G G+ + Sbjct: 186 LTYIASERIIPGYGGGM--SSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKA 243 Query: 209 LP--EKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE--NPFLNGEVIRLDGAI 257 + + + + + P L E + ++ + G I +D + Sbjct: 244 IGFIDTMIEYSYNNAPIQKTL-TADEVGNAAAFLVSPLASAITGATIYVDNGL 295 >2O2S-A nrPDB Length = 315 Score = 73.7 bits (180), Expect = 7e-14, Method: Composition-based stats. Identities = 45/301 (14%), Positives = 93/301 (30%), Gaps = 62/301 (20%) Query: 7 SVKGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLP----------NSGGEAQAKKL 54 ++G A + G A G G A A+ L GA L P SG + +KL Sbjct: 6 DLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKL 65 Query: 55 GNNCVFAPADV-------TSEKDVQTALAL------------------AKGKFGRVDVAV 89 + + A V +DV + K G +D+ V Sbjct: 66 PDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILV 125 Query: 90 NCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGV 149 + ++A+ K + + + + ++++ M + G Sbjct: 126 H----SLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNE--------GGS 173 Query: 150 IINTASVAAFEGQVGQAA-YSASKGGIVGMTLPIARDLA-PIGIRVMTIAPGLFGTPLLT 207 + + +AA G S++K + T +A + G+RV I+ G + + Sbjct: 174 AVTLSYLAAERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAAS 233 Query: 208 SLPEKVCNFLAS--------QVPFPSRLGDPAEYAHLVQAIIE--NPFLNGEVIRLDGAI 257 ++ + P R + ++ ++G + +D + Sbjct: 234 AIGKSGEKSFIDYAIDYSYNNAPL-RRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGL 292 Query: 258 R 258 Sbjct: 293 H 293 >2PTG-A nrPDB Length = 319 Score = 69.9 bits (170), Expect = 1e-12, Method: Composition-based stats. Identities = 39/314 (12%), Positives = 100/314 (31%), Gaps = 75/314 (23%) Query: 7 SVKGLVAVITGG--ASGLGLATAERLVGQGASAVL------------------------- 39 ++G A + G ++G G A + L GA ++ Sbjct: 6 DLRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFY 65 Query: 40 LDLPNSGGEAQAKKLGNNCVF---------------APADVTSEK--------DVQTALA 76 P+S A+A + + VF P +V+S K + Sbjct: 66 AQEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAE 125 Query: 77 LAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEM 136 + G++D+ V+ ++A+ K + + + + + ++++ M Sbjct: 126 AVRADVGQIDILVH----SLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLM 181 Query: 137 GQNEPDQGGQRGVIINTASVAAFEGQVGQAA-YSASKGGIVGMTLPIARDLAP-IGIRVM 194 + G + + +A+ + G S++K + +A + +RV Sbjct: 182 KE--------GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVN 233 Query: 195 TIAPGLFGTPLLTSLPEKVC--------NFLASQVPFPSRLGDPAEYAHLVQAIIE--NP 244 I+ G + +++ + ++ + P L + + ++ Sbjct: 234 CISAGPLKSRAASAIGKAGDKTFIDLAIDYSEANAPLQKEL-ESDDVGRAALFLLSPLAR 292 Query: 245 FLNGEVIRLDGAIR 258 + G + +D + Sbjct: 293 AVTGATLYVDNGLH 306 >3F4B-A nrPDB Length = 323 Score = 68.0 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 38/308 (12%), Positives = 93/308 (30%), Gaps = 78/308 (25%) Query: 17 GGASGLGLATAERLVGQGASAV------------------------LLDLPNSGGEAQAK 52 G ++G G A+ L + + +++ NS Sbjct: 16 GDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKRMQILD 75 Query: 53 KLGNNCVFAPADVTSEK-------------DVQTALALAKGKFGRVDVAVNCAGIAVASK 99 L + F D E ++ L K+G++ + V+ ++A+ Sbjct: 76 VLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVH----SLANG 131 Query: 100 TYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAF 159 K + + + + + ++ + M G +++ A+ Sbjct: 132 REVQKSLLDTSRDGYLDAISKSSYSLISLCKHFCKFMN--------SGGSVVSLTYQASQ 183 Query: 160 EGQVGQAA-YSASKGGIVGMTLPIARDLAP-IGIRVMTIAPGLFGTPLLTSLP------- 210 + G S++K + T +A L IR+ TI+ G + T++ Sbjct: 184 KVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQK 243 Query: 211 -----------------EKVCNFLASQVPFPSRLGDPAEYAHLVQAII--ENPFLNGEVI 251 + ++ P +L + + ++ E+ + G+ I Sbjct: 244 NNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLS-TDVGSVASFLLSKESSAVTGQTI 302 Query: 252 RLDGAIRM 259 +D + + Sbjct: 303 YVDNGLNI 310 >3SLK-A nrPDB Length = 795 Score = 60.3 bits (145), Expect = 9e-10, Method: Composition-based stats. Identities = 40/198 (20%), Positives = 71/198 (35%), Gaps = 38/198 (19%) Query: 12 VAVITGGASGLGLATAERLV-GQGA-SAVLLDL---PNSGGEAQAKKL---GNNCVFAPA 63 ++TGG LG A LV +G + VL+ SG +L G Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 DV + + LA + + V+ AG+ ++ T+E +VL + Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGV------SESLTVERLDQVLRPKVD 644 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM----- 178 G N++ L+ ++ ++ +SV+ G GQ Y+A+ + + Sbjct: 645 GARNLLELIDPDVA------------LVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQ 692 Query: 179 -----TLPIARD-LAPIG 190 T +A A G Sbjct: 693 SRGLPTRSLAWGPWAEHG 710 >4LIS-A nrPDB Length = 371 Score = 57.6 bits (138), Expect = 6e-09, Method: Composition-based stats. Identities = 29/183 (15%), Positives = 51/183 (27%), Gaps = 43/183 (23%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFAPADVTSE 68 ++TGG +G T L+ G V+ D + ++ G FA DVT E Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 A +D ++ A + ++ VN+ GT Sbjct: 66 ----AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPL----------DYYHVNVYGTI-- 109 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTASVA---------------AFEGQVGQAAYSASKG 173 + M ++ I+ ++S Y +K Sbjct: 110 --CLLRSMVRHNVT------NIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKF 161 Query: 174 GIV 176 I Sbjct: 162 AIE 164 >3ORF-A nrPDB Length = 251 Score = 54.9 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 73/208 (35%), Gaps = 24/208 (11%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 S ++ GG+ LG + + + + +D + + F D + Sbjct: 19 SHMSKNILVLGGSGALGAEVVKFFKSKSWNTISIDFREN--------PNADHSFTIKD-S 69 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 E+++++ + K +VD V AG + + ++ + ++D+NL F Sbjct: 70 GEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSV-----KGMIDMNLYSAF 124 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + A + Q G+ + T + AA G AY A+K + +A + Sbjct: 125 ASAHIGAKLLN--------QGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASEN 176 Query: 187 A--PIGIRVMTIAPGLFGTPLLTSLPEK 212 P G + I P TP Sbjct: 177 GGLPAGSTSLGILPVTLDTPTNRKYMSD 204 >2O2Y-A nrPDB Length = 349 Score = 52.2 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 34/268 (12%), Positives = 81/268 (30%), Gaps = 65/268 (24%) Query: 41 DLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKT 100 D ++ NN + + +DV + K+G++++ V+ ++A+ Sbjct: 85 DASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQ---KYGKINMLVH----SLANAK 137 Query: 101 YNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFE 160 K + + + L + ++ + M II+ A+ + Sbjct: 138 EVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQS--------SIISLTYHASQK 189 Query: 161 GQVGQAA-YSASKGGIVGMTLPIARDLAP-IGIRVMTIAPGLFGTPLLTSLP-------- 210 G S++K + T +A L IR+ TI+ G + T++ Sbjct: 190 VVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYEN 249 Query: 211 -----------------------EKVC--------------NFLASQVPFPSRLGDPAEY 233 E+ + P +L + Sbjct: 250 NTNQNKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLS-TDI 308 Query: 234 AHLVQAII--ENPFLNGEVIRLDGAIRM 259 + ++ E+ + G+ I +D + + Sbjct: 309 GSVASFLLSRESRAITGQTIYVDNGLNI 336 >1DIR-A nrPDB Length = 241 Score = 50.3 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 39/270 (14%), Positives = 85/270 (31%), Gaps = 54/270 (20%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 + ++ GG LG + + +D+ + + V + Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEA-------SASVIVKMTDSFT 58 Query: 69 KDVQTALALAKGKFG--RVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + A G +VD + AG A K + +++ + + + + Sbjct: 59 EQADQVTAEVGKLLGDQKVDAILCVAG-GWAGGNAKSKSLFKNCDLMWKQSIWTSTISSH 117 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA--R 184 + + + G++ + AA +G G Y +KG + + +A Sbjct: 118 LATKHL------------KEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKN 165 Query: 185 DLAPIGIRVMTIAPGLFGTPLLT-SLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIE- 242 P G + + P TP+ S+PE +S P + ++E Sbjct: 166 SGMPSGAAAIAVLPVTLDTPMNRKSMPEA---DFSSWTPL--------------EFLVET 208 Query: 243 -NPFLNG----------EVIRLDGAIRMQP 261 + ++ G +V+ DG + P Sbjct: 209 FHDWITGNKRPNSGSLIQVVTTDGKTELTP 238 >1UDA-A nrPDB Length = 338 Score = 50.3 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 57/176 (32%), Gaps = 41/176 (23%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLD----LPNSGGEAQAKKLGNNCVFAPADVTSE 68 ++TGG+ +G T +L+ G ++LD S + G + F D+ +E Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNE 62 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 + L +D ++ AG+ ++ D N+ GT + Sbjct: 63 ALMTEILHDHA-----IDTVIHFAGLKAVGESVQKPL----------EYYDNNVNGTLRL 107 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINTAS------------VAAFEGQVGQAAYSASK 172 I + I ++S V +F Q+ Y SK Sbjct: 108 ISA----------MRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSK 153 >1OOE-A nrPDB Length = 236 Score = 49.5 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 68/205 (33%), Gaps = 25/205 (12%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 G V ++ GG LG A E G + + +DL A ++ + + Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLS-------ANDQADSNILVDGNKNWT 54 Query: 69 KDVQTALALAKGKFGR--VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + Q+ L VD AG G + + +DF + D+ + + Sbjct: 55 EQEQSILEQTASSLQGSQVDGVFCVAGGW---------AGGSASSKDFVKNADLMIKQSV 105 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI-ARD 185 + A G++ T + AA Y +K + +T + A+D Sbjct: 106 WSSAIAAKL----ATTHLKPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKD 161 Query: 186 LA-PIGIRVMTIAPGLFGTPLLTSL 209 P V+TI P TP+ Sbjct: 162 SGLPDNSAVLTIMPVTLDTPMNRKW 186 >1Z45-A nrPDB Length = 699 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 34/187 (18%), Positives = 66/187 (35%), Gaps = 25/187 (13%) Query: 1 MAAACRS-VKGLVAVITGGASGLGLATAERLVGQGASAVLLD-LPNSGGEAQAK---KLG 55 M A +S + ++TGGA +G T L+ G V+ D L NS ++ A+ Sbjct: 1 MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTK 60 Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 ++ F D+ K ++ ++D ++ AG+ ++ + Sbjct: 61 HHIPFYEVDLCDRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIPL---------- 105 Query: 116 RVLDVNLMGTFNVIRL-----VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSA 170 R N++GT ++ L V+ + + G N + Y Sbjct: 106 RYYHNNILGTVVLLELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGH 165 Query: 171 SKGGIVG 177 +K I Sbjct: 166 TKYAIEN 172 >6BWL-A nrPDB Length = 328 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 42/258 (16%), Positives = 77/258 (29%), Gaps = 31/258 (12%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNC---VFAPADVTSEKD 70 ++TGGA +G +RL+ +LD + A + ++ D+ +K Sbjct: 4 LVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDKKL 63 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 V N + ++ +++D + + + +GTFN++ Sbjct: 64 VAQLFE-------------NNSFDLCYHLAASIN--VQDSIDDARATFENDTIGTFNLLE 108 Query: 131 LVAGE-MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP--IARDLA 187 + N ++ + + Y+ SK M L A L Sbjct: 109 QCLNYDVKMVFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLP 168 Query: 188 PIGIR-VMTIAPGLFGTPLLTSLPEKVCNFLASQVPF--------PSRLGDPAEYAHLVQ 238 + IR T P T + N VP L + A V Sbjct: 169 VVVIRPFNTYGP-FQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCADFVV 227 Query: 239 AIIENPFLNGEVIRLDGA 256 A + NG +I Sbjct: 228 AAGYSAKANGHIINAGTG 245 >3RFT-A nrPDB Length = 267 Score = 48.3 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 31/182 (17%), Positives = 48/182 (26%), Gaps = 49/182 (26%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ++TG A LG ERL L DL G N D+ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLS------PLDPAGPNEECVQCDLADANA 57 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 V +A D V+ GI+V F+++L N++G +N+ Sbjct: 58 VNAMVA-------GCDGIVHLGGISVEKP--------------FEQILQGNIIGLYNLYE 96 Query: 131 LVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQ------------AAYSASKGGIVGM 178 + I+ +S Y SK + Sbjct: 97 AARAH----------GQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENL 146 Query: 179 TL 180 Sbjct: 147 AR 148 >3ENK-A nrPDB Length = 341 Score = 48.3 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLD-LPNSGGEAQA---KKLGNNCVFAPADVTS 67 ++TGGA +G TA L+ G V+ D L NS EA A K G F DV+ Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSD 66 Query: 68 EKDVQTALAL 77 E+ + Sbjct: 67 ERALARIFDA 76 >2PK3-A nrPDB Length = 321 Score = 47.6 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 42/257 (16%), Positives = 78/257 (30%), Gaps = 39/257 (15%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 A+ITG A +G A L Q N N D+ + V+ Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKL-------PNVEMISLDIMDSQRVK 67 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV 132 ++ + D + A + ++ KKG N+ GT +V+ V Sbjct: 68 KVISDI-----KPDYIFHLAAKSSVKDSWLNKKG----------TFSTNVFGTLHVLDAV 112 Query: 133 AGEMGQNEPDQGGQ---RGVIINTAS-VAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 G G+I+ S V+ + Y SK + + + Sbjct: 113 RDSNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGM 172 Query: 189 IGI---RVMTIAPGLFGTPLLTSLPEKVCN-FLASQVPFPSRLGDPA------EYAHLVQ 238 I I PG + +++ + + Q P +G+ + +VQ Sbjct: 173 DIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIK-VGNLEAVRDFTDVRDIVQ 231 Query: 239 --AIIENPFLNGEVIRL 253 ++ G+V + Sbjct: 232 AYWLLSQYGKTGDVYNV 248 >4R1T-A nrPDB Length = 337 Score = 46.4 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 41/136 (30%), Gaps = 11/136 (8%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLL----DLPNSGGEAQAKKLGNNCVF 60 RSV G V +TG + + L+ +G + D P +G + + Sbjct: 5 MRSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTL 64 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 AD+ + ++ A+ D + A ++ T + Sbjct: 65 CKADLLDYQSLREAIN-------GCDGVFHTASPVTDDPEQMVEPAVIGTKNVINAAAEA 117 Query: 121 NLMGTFNVIRLVAGEM 136 N+ + A M Sbjct: 118 NVRRVVFTSSIGAVYM 133 >2Q1W-A nrPDB Length = 333 Score = 42.9 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 38/123 (30%), Gaps = 21/123 (17%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ITG +G AE L+ +G V +D +G K N F + Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDH-PNLTFVEGSIADHAL 80 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDF-QRVLDVNLMGTFNVI 129 V + + D V+ A +D+ L N +G NV+ Sbjct: 81 VNQLIGDL-----QPDAVVHTAASYKD-------------PDDWYNDTL-TNCVGGSNVV 121 Query: 130 RLV 132 + Sbjct: 122 QAA 124 >4G5H-A nrPDB Length = 363 Score = 42.5 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 47/130 (36%), Gaps = 19/130 (14%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNC--VFAPADV 65 + +ITGG G A +R + + + + + +K NN F DV Sbjct: 23 FDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYIGDV 82 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + V+TA+ VD + A + + +E + N++GT Sbjct: 83 RDSQSVETAMRD-------VDYVFHAA------ALKQVPSCEFFPVEA----VKTNIIGT 125 Query: 126 FNVIRLVAGE 135 NV++ + Sbjct: 126 ENVLQSAIHQ 135 >5N2I-A nrPDB Length = 232 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 24/83 (28%) Query: 2 AAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA 61 V GL + GG G A R G +L +A A +LG Sbjct: 11 PHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVR 70 Query: 62 PADVTSEKDVQTALALAKGKFGR 84 D + + +A G Sbjct: 71 GMDNAGAAEAGDVVIVAVPWDGH 93 >1I3M-A nrPDB Length = 348 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 30/194 (15%), Positives = 53/194 (27%), Gaps = 49/194 (25%) Query: 13 AVITGGASGLGLATAERLVGQGA-SAVLLDLPN---------SGGEAQAKKLGNNCVFAP 62 ++TGGA +G T L+ G V+ + N + G + F Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64 Query: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 D+ + +Q ++ AG+ ++ VNL Sbjct: 65 MDILDQGALQRLFKKY-----SFMAVIHFAGLKAMGESVQKPL----------DYYRVNL 109 Query: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-------------AYS 169 GT + M + ++ ++S A G Y Sbjct: 110 TGTIQL----LEIMKAHGVK------NLVFSSS-ATVYGNPQYLPLDEAHPTGGCTNPYG 158 Query: 170 ASKGGIVGMTLPIA 183 SK I M + Sbjct: 159 KSKFFIEEMIRDLC 172 >2HUN-A nrPDB Length = 336 Score = 41.0 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 62/180 (34%), Gaps = 30/180 (16%) Query: 14 VITGGASGLGLATAERLVGQ--GASAVLLD---LPNSGGEAQAKKLGNNCVFAPADVTSE 68 ++TGG +G ++ + + +D ++ + + F DV Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVKGDVADY 66 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 + V+ + +VD V+ A + + E F L N++GT+ + Sbjct: 67 ELVKELVR-------KVDGVVHLAAESHV-------DRSISSPEIF---LHSNVIGTYTL 109 Query: 129 ---IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG----IVGMTLP 181 IR E+ G I+ S + + + YSA+K ++G T Sbjct: 110 LESIRRENPEVRFVHVSTDEVYGDILK-GSFTENDRLMPSSPYSATKAASDMLVLGWTRT 168 >1VL0-A nrPDB Length = 292 Score = 40.2 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 26/180 (14%), Positives = 50/180 (27%), Gaps = 55/180 (30%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 +ITG LG ++L G+ + D+ + D+T+ V Sbjct: 16 LITGANGQLGREIQKQLKGKNVEVIPTDVQD------------------LDITNVLAVNK 57 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 + +V +NCA E + +N +G N+ Sbjct: 58 FFNE-----KKPNVVINCAAHT----------AVDKCEEQYDLAYKINAIGPKNLAAAAY 102 Query: 134 GEMGQNEPDQGGQRGVIINTASVAAFEGQV-----------GQAAYSASKGGIVGMTLPI 182 I+ ++ F+G+ Q+AY +K + Sbjct: 103 -----------SVGAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >3VPX-A nrPDB Length = 364 Score = 40.2 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 24/70 (34%), Gaps = 7/70 (10%) Query: 7 SVKGLVAVITGGASGLG---LATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 S+ G + G+G A E L +GA ++ D+ + G V Sbjct: 170 SLAGKTVAV----QGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINE 225 Query: 64 DVTSEKDVQT 73 + E D+ Sbjct: 226 IYSQEADIFA 235 >1LU9-A nrPDB Length = 287 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 32/80 (40%) Query: 3 AACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAP 62 AA SVKG AV+ G +G+ +A L G+GA VL +A A + Sbjct: 112 AAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNV 171 Query: 63 ADVTSEKDVQTALALAKGKF 82 + D A A+ F Sbjct: 172 TAAETADDASRAEAVKGAHF 191 >1BXK-A nrPDB Length = 355 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 27/188 (14%), Positives = 57/188 (30%), Gaps = 31/188 (16%) Query: 11 LVAVITGGASGLGLATAERLVGQGAS-AVLLDLPNSGGEAQAKKL---GNNCVFAPADVT 66 +ITGGA +G A ++ + + V++D G + F D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 ++ + D ++ A + ++ + ++ N++GT+ Sbjct: 62 DRAELARVFTEH-----QPDCVMHLAAESHVDRSIDGPAAF----------IETNIVGTY 106 Query: 127 NVIRLVAGEMGQNEPDQGGQ-RGVIINTASVAA-----------FEGQVGQAAYSASKGG 174 ++ D+ R I+T V + YSASK Sbjct: 107 TLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKAS 166 Query: 175 IVGMTLPI 182 + Sbjct: 167 SDHLVRAW 174 >4J6F-A nrPDB Length = 382 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 29/74 (39%), Gaps = 2/74 (2%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 M R G ++TG + G+G A + +GA V + + G EA +G V Sbjct: 198 MLERARLAAGETVLVTGASGGVGSAIIQLARARGA--VPIAVAGPGKEAAMLDIGAQAVV 255 Query: 61 APADVTSEKDVQTA 74 + V+ A Sbjct: 256 TRGQGDLAEAVEAA 269 >1GY8-A nrPDB Length = 397 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 35/173 (20%), Positives = 61/173 (35%), Gaps = 48/173 (27%) Query: 13 AVITGGASGLGLATAERLVGQ-GASAVLLDL---------PNSGGEAQAKKLGNN----- 57 ++ GGA +G L+ S V++D E A+KL + Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 58 ------CVFAPADVTSEKDVQTALALAKGKFGRVDVAVN-CAGIAVASKTYNLKKGQTHT 110 DV +E L + G +D V+ CA +AV + Sbjct: 65 PWADRYAALEVGDVRNED----FLNGVFTRHGPIDAVVHMCAFLAVG-----------ES 109 Query: 111 LEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163 + D + D N++G +++ M ++ D+ II ++S AA G Sbjct: 110 VRDPLKYYDNNVVGILRLLQA----MLLHKCDK------IIFSSS-AAIFGNP 151 >2GN9-A nrPDB Length = 344 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 51/176 (28%), Gaps = 35/176 (19%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAER-LVGQGASAVLLDLPNSGGEAQAKKLGN--N 57 M + +ITGG G + L A +++ + +++ N Sbjct: 12 MPNHQNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPR 71 Query: 58 CVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRV 117 F DV + + AL VD+ ++ A + + Sbjct: 72 MRFFIGDVRDLERLNYALE-------GVDICIHAAAL-KHVPIAEYNPLEC--------- 114 Query: 118 LDVNLMGTFNVIRLVAG-EMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASK 172 + N+MG NVI + Q + IN Y A+K Sbjct: 115 IKTNIMGASNVINACLKNAISQVIALSTDKAANPINL--------------YGATK 156 >1R66-A nrPDB Length = 337 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 52/173 (30%), Gaps = 31/173 (17%) Query: 14 VITGGASGLGLATAERLVGQGA-------SAVLLD---LPNSGGEAQAKKLGNNCVFAPA 63 ++TGGA +G +L+ GA ++LD + F Sbjct: 4 LVTGGAGFIGSHFVRQLLA-GAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHG 62 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 D+ L + VD V+ A + ++ T + N+ Sbjct: 63 DIRDAG-------LLARELRGVDAIVHFAAESHVDRSIAGASVFT----------ETNVQ 105 Query: 124 GTFNVIRLVAGEMGQNEPDQGGQ--RGVIINTASVAAFEGQVGQAAYSASKGG 174 GT +++ G I ++ S + Y+ASK G Sbjct: 106 GTQTLLQCAVDAGVGRVVHVSTDEVYGSI-DSGSWTESSPLEPNSPYAASKAG 157 >5INT-A nrPDB Length = 220 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 48/138 (34%), Gaps = 35/138 (25%) Query: 5 CRSVKGLVAVITGG---------------ASG-LGLATAERLVGQGASAVLLDLPNSGGE 48 +++G +IT G +SG +G A AE V GA +L+ Sbjct: 1 SNALQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS------- 53 Query: 49 AQAKKLGNNCVFAPADVT--SEKDVQTALALAKGKFGRVDVAVNCAGIAVASK----TYN 102 G + P VT + Q L + VDV + A +A Sbjct: 54 ------GPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVADYRPKYVHDNK 107 Query: 103 LKKGQTHTLEDFQRVLDV 120 +KK + + +R +D+ Sbjct: 108 MKKKNGDAVIELERTVDI 125 >5K1S-A nrPDB Length = 362 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%) Query: 9 KGLVAVITGGASGLGLATAERLVG-QGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 G +ITG + G+GL+ + +L GA + + + +A K+ G + V + Sbjct: 183 AGETVLITGASGGVGLS-SVQLARLDGARVIAVTSSEAKVQAL-KEAGADEVIVSRGLDF 240 Query: 68 EKDVQTALALAKGKFGRVDVAV 89 DV+ + + VDVAV Sbjct: 241 ASDVRK-----RTQGAGVDVAV 257 >6ACF-A nrPDB Length = 367 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 21/56 (37%), Gaps = 7/56 (12%) Query: 7 SVKGLVAVITGGASGLG---LATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV 59 S++G V + G+G L +GA ++ D+ ++ G V Sbjct: 170 SLEGKVVAV----QGVGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAV 221 >2Z95-A nrPDB Length = 345 Score = 38.7 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 8 VKGLVAVITGGASGL-GLATAERLVGQGASAVLLDLPN-SGGEAQAKKLG--NNCVFAPA 63 + G A+ITG G G A+ L+ +G D + + K+LG N+ Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHM 59 Query: 64 DVTSEKDVQTALALA 78 D+ ++ + Sbjct: 60 DLLEFSNIIRTIEKV 74 >2PZM-A nrPDB Length = 330 Score = 38.3 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 50/171 (29%), Gaps = 30/171 (17%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 +ITGGA LG E + QG +++D + G+ + VT ++ Sbjct: 24 LITGGAGCLGSNLIEHWLPQGHEILVID-NFATGKREVLPPVAGLSVIEGSVTDAGLLER 82 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVA 133 A K V+ A +D+ N+ G+ NV + + Sbjct: 83 AFDSFKPTH-----VVHSAAAYKD-------------PDDWAEDAATNVQGSINVAKAAS 124 Query: 134 GE-----MGQNEPDQGGQRGVI-INTASVAAFEGQVGQAAYSASKGGIVGM 178 + G+ + I S +Y SK Sbjct: 125 KAGVKRLLNFQTALCYGRPATVPIPIDS-----PTAPFTSYGISKTAGEAF 170 >4PVC-A nrPDB Length = 342 Score = 37.9 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 27/81 (33%), Gaps = 2/81 (2%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 ++G + + L+ + + E + GNN F+ V + Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 73 TALALAKGKFGR-VDVAVNCA 92 A K G+ + + ++ A Sbjct: 63 -AFDHVFQKHGKDIKIVLHTA 82 >4K28-A nrPDB Length = 269 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 9 KGLVAVITGGASGLGLATAERLVGQG-ASAVLLDLPNSGGEAQAKKLGN 56 G A++ G G+G A A L G AS L D + A + LGN Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGN 171 >4EUF-A nrPDB Length = 418 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 32/96 (33%), Gaps = 17/96 (17%) Query: 11 LVAVITGGASGLGLA--TAERLVGQGASAVLLDLPNSGGE---------------AQAKK 53 +I G +SG GLA + G A + + + AKK Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 54 LGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAV 89 G D S + + K +FG++D+ V Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >2C20-A nrPDB Length = 330 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 51/179 (28%), Gaps = 33/179 (18%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 +I GGA +G ++LV +G S V++D G A G F D+ + ++ Sbjct: 5 LICGGAGYIGSHAVKKLVDEGLSVVVVD-NLQTGHEDAITEGAK--FYNGDLRDKAFLRD 61 Query: 74 ALAL----AKGKFGRVDVAV-----------NCAGIAVASKTYNLKK-----------GQ 107 A F D V N + + Sbjct: 62 VFTQENIEAVMHFAA-DSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAA 120 Query: 108 THTLEDFQRVLD---VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163 T+ D + + N T+ +L +M R I +VA Sbjct: 121 TYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGATPNG 179 >6DEB-A nrPDB Length = 285 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 40/117 (34%), Gaps = 17/117 (14%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 + A ++G AVI G ++ +G A L+ GA+ + + + Sbjct: 151 LKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDL---------SLYT 201 Query: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRV 117 AD+ +A R D V I V L+ G+ DF+ V Sbjct: 202 RQADLI-------IVAAGCVNLLRSD-MVKEGVIVVDVGINRLESGKIVGDVDFEEV 250 >5F5N-A nrPDB Length = 289 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 1/72 (1%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ++TG G AT L+ +G V + + G +A D+ + Sbjct: 2 RTILVTGATGTQGGATVRALLARG-RPVRALVRDPGTDAARALAAAGVSLVTGDLNDQAS 60 Query: 71 VQTALALAKGKF 82 ++ A+A G F Sbjct: 61 LRAAMADVHGVF 72 >6G2J-P nrPDB Length = 377 Score = 37.2 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 38/102 (37%), Gaps = 11/102 (10%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL---LDLPNSGGEAQAKKLGNNCVFAPA 63 SV G+VA + G LG L G+ ++ D+ + LG F Sbjct: 50 SVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQ-LTFLEW 108 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKK 105 D + ++ A+ + +V +N G ++ ++ + Sbjct: 109 DARDKDSIRKAVQHS-------NVVINLIGREWETRNFDFED 143 >5ENV-A nrPDB Length = 347 Score = 37.2 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 18/130 (13%) Query: 15 ITGGASGLGLATAERLVGQ-GASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 I+G A GLG + A + G + +D G E + +G D T EKD+ Sbjct: 175 ISGAAGGLG-SLAVQYAKAMGYRVLGID-GGEGKEELFRSIGGEVFI---DFTKEKDIVG 229 Query: 74 ALALAKG--KFGRVDVAVNCAGIAVASKTYN---------LKKGQTHTLEDFQRVL-DVN 121 A+ A G ++V+V+ A I +++ + G + F +V+ ++ Sbjct: 230 AVLKATDGGAHGVINVSVSEAAIEASTRYVRANGTTVLVGMPAGAKCCSDVFNQVVKSIS 289 Query: 122 LMGTFNVIRL 131 ++G++ R Sbjct: 290 IVGSYVGNRA 299 >1WVG-A nrPDB Length = 359 Score = 36.8 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 57/179 (31%), Gaps = 38/179 (21%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA--QAKKLGNNCVFAPADVT 66 +G +TG G + L GA L + + +L + D+ Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHIGDIR 67 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + +++++A + ++ + A A L Q + N+MGT Sbjct: 68 DFEKLRSSIAEF-----KPEIVFHMA----AQPLVRLSYEQPI------KTYSTNVMGTV 112 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTAS---------VAAFE---GQVGQAAYSASKG 173 +++ V Q G ++N S V + G YS SKG Sbjct: 113 HLLETV---------KQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >2DFV-A nrPDB Length = 347 Score = 36.8 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 10/81 (12%) Query: 9 KGLVAVITGGA--SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 G +ITG LG+A A+ GA V++ P+ AKK+G + V P Sbjct: 166 SGKSVLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSDFRRELAKKVGADYVINPF--- 219 Query: 67 SEKDVQTALALAKGKFGRVDV 87 E+DV + G VDV Sbjct: 220 -EEDVVKEVMDITDGNG-VDV 238 >4A10-A nrPDB Length = 447 Score = 36.8 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 1/81 (1%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 +G + +I G + GLG + A + V G + + ++ EA + LG + V A++ Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 69 KDVQTALALAKGKFGRVDVAV 89 D+ ++ V Sbjct: 279 DDIADDPRRVVETGRKLAKLV 299 >4EJ6-A nrPDB Length = 370 Score = 36.4 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 6/88 (6%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 G I GG +GL T + GA+ V+L + A+++G P S Sbjct: 182 AGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDP----SA 236 Query: 69 KDVQTALALAKGKF-GRVDVAVNCAGIA 95 DV A+A G G VDV + CAG+A Sbjct: 237 GDVVEAIAGPVGLVPGGVDVVIECAGVA 264 >4J2O-A nrPDB Length = 363 Score = 36.4 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 41/129 (31%), Gaps = 19/129 (14%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK--LGNNCVFAPADV 65 K V +ITGG G A +R + + + + + +K F DV Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYIGDV 80 Query: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125 + A VD + A + + H +E + N++GT Sbjct: 81 RDYNSILNATR-------GVDYIYHAA------ALKQVPSCEFHPMEA----VKTNVLGT 123 Query: 126 FNVIRLVAG 134 NV+ Sbjct: 124 ENVLEAAIQ 132 >3IP1-A nrPDB Length = 404 Score = 36.4 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEK 69 G VI GG +GLA L GAS V+L P+ AK+LG + V D T E Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVI---DPTKEN 269 Query: 70 DVQTALA 76 V+ L Sbjct: 270 FVEAVLD 276 >6GCS-E nrPDB Length = 375 Score = 36.0 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 36/103 (34%), Gaps = 10/103 (9%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV--FAPAD 64 S G A + G LG +L G + V+ + K G+ V F D Sbjct: 50 SRTGYTATVFGANGFLGSYLTAKLAKHGTTVVVP-YREEMAKRHLKVTGDLGVVNFLEMD 108 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQ 107 + + + + A+ + D+ VN G +K +N Sbjct: 109 LRNLESIDEAVRHS-------DIVVNLIGREYETKNFNYYDVH 144 >3OND-A nrPDB Length = 488 Score = 36.0 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 M A + G VAV+ G +G A L GA ++ ++ + QA G + Sbjct: 256 MRATDVMIAGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEI-DPICALQATMEGLQVLT 313 Query: 61 APADVTSEKDV 71 DV SE D+ Sbjct: 314 LE-DVVSEADI 323 >1OC2-A nrPDB Length = 348 Score = 36.0 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 29/193 (15%), Positives = 55/193 (28%), Gaps = 33/193 (17%) Query: 11 LVAVITGGASGLGLATAERL---VGQGASAVLLDLPNSGGEAQAKK-LGNNCVFAPADVT 66 ++TGGA +G + VL L +G +A + LG+ D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 + V A A D V+ A + + N + N +GT+ Sbjct: 65 DAELVDKLAAKA-------DAIVHYAAESHNDNSLNDPSPF----------IHTNFIGTY 107 Query: 127 NVIRLVAGE-MGQNEPDQGGQRGVIINTASVAAFEGQVG-----------QAAYSASKGG 174 ++ + + G + + G + YS++K Sbjct: 108 TLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAA 167 Query: 175 IVGMTLPIARDLA 187 + R Sbjct: 168 SDLIVKAWVRSFG 180 >2HK7-A nrPDB Length = 269 Score = 34.8 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 VK ++ G G A LV +GA L + A+K V +P +V Sbjct: 121 VKEKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVID 179 Query: 68 EKDV 71 + V Sbjct: 180 KVQV 183 >2EER-A nrPDB Length = 347 Score = 34.8 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 2/51 (3%) Query: 11 LVAVITGGASGLGL-ATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 V+ G GLG A GA+ + +D+ EA AK+ G + V Sbjct: 172 KTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEA-AKRAGADYVI 221 >6ACQ-A nrPDB Length = 302 Score = 34.8 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 2/42 (4%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE 48 S V VI GA +G A+ +G VL D+ + + Sbjct: 19 SHMKKVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDEFVD 58 >4KTT-E nrPDB Length = 327 Score = 34.5 bits (78), Expect = 0.043, Method: Composition-based stats. Identities = 18/123 (14%), Positives = 33/123 (26%), Gaps = 26/123 (21%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 ++TG LG A + AV + + F ++ Sbjct: 22 RRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK-----------FEQVNLLD--- 67 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIR 130 A+ F V V+CA N + +N+ + N+ + Sbjct: 68 -SNAVHHIIHDFQP-HVIVHCAAERRPDVVENQPDAAS----------QLNVDASGNLAK 115 Query: 131 LVA 133 A Sbjct: 116 EAA 118 >1KEU-A nrPDB Length = 361 Score = 34.5 bits (78), Expect = 0.045, Method: Composition-based stats. Identities = 26/206 (12%), Positives = 53/206 (25%), Gaps = 39/206 (18%) Query: 14 VITGGASGLGLATAERLVGQGASAVL----LDLPNSGGEAQAKKLGNNCVFAPADVTSEK 69 +ITGGA +G A ++ V+ L + N F AD+ Sbjct: 4 LITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDSA 63 Query: 70 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVI 129 ++ + D ++ A + ++ ++ N++GT+ ++ Sbjct: 64 EITRIFEQY-----QPDAVMHLAAESHVDRSITGPAAF----------IETNIVGTYALL 108 Query: 130 RLVAGEMGQNEPDQGGQRG--------------------VIINTASVAAFEGQVGQAAYS 169 + D+ + + YS Sbjct: 109 EVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYS 168 Query: 170 ASKGGIVGMTLPIARDLAPIGIRVMT 195 ASK + R I Sbjct: 169 ASKASSDHLVRAWRRTYGLPTIVTNC 194 >1U3W-A nrPDB Length = 374 Score = 34.5 bits (78), Expect = 0.045, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 51/155 (32%), Gaps = 26/155 (16%) Query: 11 LVAVITGGA-------SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 VA +T G+ G+GL+ GA+ ++ N A+AK+LG P Sbjct: 185 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 244 Query: 64 DVTSEKD------VQTALALAKGKFGRVDVAVNC-------------AGIAVASKTYNLK 104 D + + G++D + G+ S+ ++ Sbjct: 245 DYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN 304 Query: 105 KGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQN 139 T ++ + +V +LVA M + Sbjct: 305 PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKK 339 >1O89-A nrPDB Length = 345 Score = 34.5 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 14/35 (40%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGE 48 V+TG + G+G L G V + S E Sbjct: 172 VVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHE 206 >2EXX-A nrPDB Length = 306 Score = 34.5 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 26/76 (34%), Gaps = 2/76 (2%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQG-ASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 V + V+ GG G + A L+ G ++ A+ +L D Sbjct: 9 VDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRL-QGAEVVQGDQD 67 Query: 67 SEKDVQTALALAKGKF 82 + ++ AL A F Sbjct: 68 DQVIMELALNGAYATF 83 >1ZZE-A nrPDB Length = 342 Score = 34.1 bits (77), Expect = 0.056, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 51/157 (32%), Gaps = 25/157 (15%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 +G + ++TG + E+L+ G S K+ D Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKR---------WDAKYP 60 Query: 69 KDVQTALALAKGKFGRVDVAVNC-AGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 127 +TA+ K G D + AG+A + + + V+ + GT N Sbjct: 61 GRFETAVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNK-------YDEVVTPAIGGTLN 113 Query: 128 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVG 164 +R A + ++ +++V+A + Sbjct: 114 ALRAAA--------ATPSVKRFVLTSSTVSALIPKPN 142 >4WOK-A nrPDB Length = 336 Score = 34.1 bits (77), Expect = 0.058, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 4/65 (6%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 ++ GGA +G TA+ L GQG + V+ D S G A + G+ F D+ + + Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVVYD-NLSTGHQSAVRWGD---FVEGDILDQARLV 69 Query: 73 TALAL 77 + Sbjct: 70 ETMEK 74 >2NNL-D nrPDB Length = 337 Score = 34.1 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 25/79 (31%), Gaps = 5/79 (6%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA-----QAKKLGNNCVFAPA 63 + +TG + +G RL+ +G + + + K + A Sbjct: 4 QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKA 63 Query: 64 DVTSEKDVQTALALAKGKF 82 D+ E A+ G F Sbjct: 64 DLADEGSFDEAIKGCTGVF 82 >5YWN-A nrPDB Length = 334 Score = 34.1 bits (77), Expect = 0.065, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 48/147 (32%), Gaps = 22/147 (14%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 ++G L ++ +G V G K G++ + +V + + Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSY---EVVKVLEQK 61 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV 132 A A K V + ++ A T +ED ++ + L+ N + V Sbjct: 62 GAFDEALKKHPEVTIFLHTA------------SPVTFEVEDTEKEI---LIPAINGTKYV 106 Query: 133 AGEMGQNEPDQGGQRGVIINTASVAAF 159 + P ++ T+SV A Sbjct: 107 LQSIKDVAPQIT----RVVYTSSVVAM 129 >4UUP-A nrPDB Length = 341 Score = 34.1 bits (77), Expect = 0.066, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 33/103 (32%), Gaps = 19/103 (18%) Query: 13 AVITGGASGLGLATAERLVGQ---GASAVLLDLPN-----SGGEAQAKKLGNNCVFAPAD 64 +ITG A +G A A R+ G V+L L E +L + A Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 65 VTSEKDVQTALALAKGKF-----------GRVDVAVNCAGIAV 96 V + D + A F R D+ AGI Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFK 109 >1YB5-A nrPDB Length = 351 Score = 33.7 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 41/114 (35%), Gaps = 7/114 (6%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 G ++ G + G+GLA + G + G+ + G + VF +V Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE-GQKIVLQNGAHEVFNHREVNYI 228 Query: 69 KDVQTALALAKGKFGRVDVAVNC-AGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121 ++ + +D+ + A + ++ L G + + +++N Sbjct: 229 DKIKKYVGE-----KGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEIN 277 >5GUP-L nrPDB Length = 377 Score = 33.3 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 36/101 (35%), Gaps = 9/101 (8%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG--NNCVFAPAD 64 SV G+VA + G LG L G+ ++ + +G +F + Sbjct: 50 SVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFMEWN 109 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKK 105 + ++ + + +V +N G +K ++ + Sbjct: 110 GKDKDSIRKVVEHS-------NVVINLVGREWETKNFDFED 143 >1EE2-A nrPDB Length = 373 Score = 32.9 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 51/157 (32%), Gaps = 26/157 (16%) Query: 11 LVAVITGGA-------SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 VA +T G+ G+GL+ GA+ ++ N A+AK++G P Sbjct: 184 KVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQ 243 Query: 64 DVTSEKD------VQTALALAKGKFGRVDVAVNC-------------AGIAVASKTYNLK 104 D + + GR+D V G+ S+ ++ Sbjct: 244 DYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMN 303 Query: 105 KGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEP 141 + ++ + +V +LVA M + Sbjct: 304 PMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFA 340 >2Q4B-A nrPDB Length = 253 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 25/78 (32%), Gaps = 9/78 (11%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 71 ++TG + G ++L V L S + K+G D+T + Sbjct: 6 TVLVTGASGRTGQIVYKKLKEGSDKFVAKGLVRSAQGKE--KIGGEADVFIGDITDADSI 63 Query: 72 QTALALAKGKFGRVDVAV 89 A F +D V Sbjct: 64 NPA-------FQGIDALV 74 >4KDR-A nrPDB Length = 223 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 29/84 (34%), Gaps = 15/84 (17%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDL---PNSGGEAQAKKLGNNCVFAPAD 64 + G + G G+ AE + +GA+ LD+ P + A + G + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ-- 115 Query: 65 VTSEKDVQTALALAKGKFGRVDVA 88 +T A G+ DV Sbjct: 116 -------ETVEEHAAKHAGQYDVV 132 >3DFZ-A nrPDB Length = 223 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 33/111 (29%), Gaps = 18/111 (16%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAER----LVGQGASAVLLDLPNSGGEAQAKKLGN 56 M +KG ++ GG + A R + +GA+ ++ S + + G Sbjct: 22 MYTVMLDLKGRSVLVVGGGT-----IATRRIKGFLQEGAAITVVAPTVSAEINEWEAKGQ 76 Query: 57 ----NCVFAPADVTS-----EKDVQTALALAKGKFGRVDVAVNCAGIAVAS 98 D+ + A+ + + D VN A Sbjct: 77 LRVKRKKVGEEDLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMASSFSDG 127 >4KDC-A nrPDB Length = 246 Score = 32.5 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 29/84 (34%), Gaps = 15/84 (17%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDL---PNSGGEAQAKKLGNNCVFAPAD 64 + G + G G+ AE + +GA+ LD+ P + A + G + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ-- 115 Query: 65 VTSEKDVQTALALAKGKFGRVDVA 88 +T A G+ DV Sbjct: 116 -------ETVEEHAAKHAGQYDVV 132 >2C54-A nrPDB Length = 379 Score = 32.5 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 12/32 (37%) Query: 15 ITGGASGLGLATAERLVGQGASAVLLDLPNSG 46 ITG + A RL +G + D + Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKNE 65 >3PEF-A nrPDB Length = 287 Score = 32.1 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 33/101 (32%), Gaps = 16/101 (15%) Query: 21 GL-GLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE--------KDV 71 G+ G A A+ LV G S + + E A LG P +V D Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAA-LGAERAATPCEVVESCPVTFAMLADP 68 Query: 72 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE 112 A + GK G ++ GI ++ T + Sbjct: 69 AAAEEVCFGKHGVLE------GIGEGRGYVDMSTVDPATSQ 103 >2VN8-A nrPDB Length = 375 Score = 32.1 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 32/100 (32%), Gaps = 10/100 (10%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 ++ G +I G + G+G + + A + + +KLG + Sbjct: 178 NDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQD--ASELVRKLGAD------ 229 Query: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNL 103 DV K ++ D ++ G + + + Sbjct: 230 DVIDYKS--GSVEEQLKSLKPFDFILDNVGGSTETWAPDF 267 >4KUG-A nrPDB Length = 290 Score = 31.8 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 4/44 (9%), Positives = 14/44 (31%), Gaps = 1/44 (2%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL 54 + G + +G + +G ++ D+ + + Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATI 44 >3R9I-A nrPDB Length = 260 Score = 31.8 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 17/38 (44%), Gaps = 5/38 (13%) Query: 11 LVAVITGGASGLGL-----ATAERLVGQGASAVLLDLP 43 + V+T G G+G A A L +G V++D Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFA 40 >4J90-A nrPDB Length = 222 Score = 31.8 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 15/43 (34%), Gaps = 3/43 (6%) Query: 21 GLGL---ATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 GLG + + L G + +D+ A A + + Sbjct: 13 GLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIA 55 >3BIC-A nrPDB Length = 762 Score = 31.8 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 31/104 (29%), Gaps = 18/104 (17%) Query: 26 TAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKF--- 82 A G + L + E + + + T +T + + Sbjct: 624 IATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVS-TLAAGHKTLVPELIKELNSL 682 Query: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 GR D+ V C G+ +D++ + +V + F Sbjct: 683 GRPDILVMCGGVIPP--------------QDYEFLFEVGVSNVF 712 >1JPH-A nrPDB Length = 388 Score = 31.8 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 22/69 (31%), Gaps = 8/69 (11%) Query: 28 ERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADV------TSEKDVQTALALAKGK 81 E L G V LD +A++ V ++ SE+++ + Sbjct: 291 EELAQAGYEVVGLDWT--VAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDD 348 Query: 82 FGRVDVAVN 90 FG N Sbjct: 349 FGPHRYIAN 357 >3NJ4-A nrPDB Length = 435 Score = 31.4 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 50/158 (31%), Gaps = 23/158 (14%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 G VAV+ G +G A+ L G GA ++ ++ A + +VT+ Sbjct: 215 AGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAME--------GYEVTTM 265 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHT-LEDFQRVLDVNLMGTFN 127 + + G +D+ + +K + F +DV + Sbjct: 266 DEACQEGNIFVTTTGCIDII-------LGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENA 318 Query: 128 VIRLVAGEMGQNEPDQGGQR------GVIINTASVAAF 159 V ++ + G+R G ++N Sbjct: 319 VEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGH 356 >3FBG-A nrPDB Length = 346 Score = 31.4 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 3/52 (5%) Query: 9 KGLVAVITGGASGLGLATAERLVGQ-GASAVLLDLPNSGGEAQAKKLGNNCV 59 +G +I GA G+G + A ++ G + N E KK+G + V Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIEWT-KKMGADIV 199 >4DGK-A nrPDB Length = 501 Score = 31.4 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 15 ITGGASGLGLATAERLVGQGASAVLLDLPNS--GGEAQAKKLGNNCVFAPADVTSEKDVQ 72 + G G GLA A RL G +LL+ + G + G P +T ++ Sbjct: 6 VIGAGFG-GLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAIE 64 Query: 73 TALALAKGKF 82 ALA + Sbjct: 65 ELFALAGKQL 74 >1HSO-A nrPDB Length = 374 Score = 31.4 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 50/154 (32%), Gaps = 26/154 (16%) Query: 12 VAVITGGA-------SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 VA +T G+ G+GL+ GA+ ++ N A+AK+LG P D Sbjct: 186 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 245 Query: 65 VTSEKD------VQTALALAKGKFGRVDVAVNC-------------AGIAVASKTYNLKK 105 + + GR+D + G+ S+ ++ Sbjct: 246 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 305 Query: 106 GQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQN 139 T ++ + V +LVA M + Sbjct: 306 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKK 339 >4XRR-A nrPDB Length = 456 Score = 31.4 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 31/102 (30%), Gaps = 2/102 (1%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDL-PNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 V+ GA +G A L G+GA V +D P + + +A + V Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAATG 77 Query: 73 TALALA-KGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED 113 A G DV + G + + E Sbjct: 78 RLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQLVAACEQ 119 >5JXW-A nrPDB Length = 498 Score = 31.4 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 32/167 (19%), Positives = 51/167 (30%), Gaps = 23/167 (13%) Query: 5 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + + G V+ G +G A+ L G GA ++ ++ + QA G D Sbjct: 266 IQMLAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEI-DPICALQASMEGYQVSVLE-D 322 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV---- 120 V SE D+ G DV I V + + F +DV Sbjct: 323 VVSEADIF------ITATGNKDV------ITVEHMRKMKENAYIANIGHFDDEIDVYGLE 370 Query: 121 NLMG--TFNVIRLVAGEMG--QNEPDQGGQRGVIINTASVAAFEGQV 163 N G V + V + +G ++N V Sbjct: 371 NYPGIKVIEVKQNVHKFTFPDTQKSVILLCKGRLVNLGCATGHPPLV 417 >3COS-A nrPDB Length = 381 Score = 31.4 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 13/99 (13%) Query: 18 GASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALAL 77 G G+GL+ GAS ++ NS +AK LG D + +D+ + Sbjct: 206 GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT------DCLNPRDLHKPIQE 259 Query: 78 AKGKF--GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDF 114 + G VD A++CAG + +K T + Sbjct: 260 VIIELTKGGVDFALDCAGGSET-----MKAALDCTTAGW 293 >6H0D-A nrPDB Length = 403 Score = 31.0 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 21/54 (38%), Gaps = 4/54 (7%) Query: 12 VAVITGGASG----LGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA 61 VA+I A G L A A + G + ++ S E + +G + F Sbjct: 258 VALIYASAYGNTSTLAQAIARGITKAGVAVTAINAETSNAEEIKEAIGKSAGFI 311 >3R7T-A nrPDB Length = 419 Score = 31.0 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 A +KG A+ T G G+G + A+++ G L P EA K N F Sbjct: 116 AKEKLKGKNAIGTTG-KGIGPSYADKINRTGHRVGELLEPQRLCEALIKDFEANKTFFEM 174 >3DMF-A nrPDB Length = 381 Score = 31.0 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 29/84 (34%), Gaps = 10/84 (11%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 V+G + G G A L GA V ++ + + K L N + Sbjct: 232 VRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANAL-------K 281 Query: 68 EKDVQTALALAKGKFGRVDVAVNC 91 + + + + A + R D+ V Sbjct: 282 AQALHSDVDEALTEEARFDIIVTN 305 >1E3J-A nrPDB Length = 352 Score = 31.0 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 5/85 (5%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEK 69 G ++ G +GL + GA V E AK G + V D E+ Sbjct: 169 GTTVLVIGAGP-IGLVSVLAAKAYGAFVVCTARSPRRLE-VAKNCGAD-VTLVVDPAKEE 225 Query: 70 DVQTALALAKGKFGRV-DVAVNCAG 93 + + + + G + +V ++C+G Sbjct: 226 E-SSIIERIRSAIGDLPNVTIDCSG 249 >3SXP-A nrPDB Length = 362 Score = 31.0 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 34/215 (15%), Positives = 61/215 (28%), Gaps = 54/215 (25%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQ--GASAVLLDLPNSG----------GEAQAKKLG 55 ++ +ITGGA +G A A V+LD S +G Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 115 AD+ + D++ L D + A ++ + + Sbjct: 68 FKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQ------------E 109 Query: 116 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA-------- 167 V+ N N++ + ++ +I +S A G Sbjct: 110 LVMKTNYQAFLNLLEIA-----------RSKKAKVIYASS-AGVYGNTKAPNVVGKNESP 157 Query: 168 ---YSASKGGIVGMTLPIARDLAPIGIR-VMTIAP 198 Y SK + L + D +G+R P Sbjct: 158 ENVYGFSKLCMDEFVLSHSNDNVQVGLRYFNVYGP 192 >5B6K-A nrPDB Length = 366 Score = 31.0 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 25/81 (30%), Gaps = 8/81 (9%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPADVTSE 68 ++G + +L+ Q + G+ + G+ D++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 69 KDVQTALALAKGKFGRVDVAV 89 TA K G+ D+ V Sbjct: 83 ----TAFDHVFEKHGK-DIKV 98 >6C55-A nrPDB Length = 340 Score = 31.0 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 ++G + G S G A A+ L G V+ P + AK+ G + VF A+ Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDK-AKEDGFD-VFPVAEAVK 71 Query: 68 EKDV 71 + DV Sbjct: 72 QADV 75 >3F6S-A nrPDB Length = 148 Score = 31.0 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 29/79 (36%), Gaps = 4/79 (5%) Query: 11 LVAVITGGASGLGLATAERL----VGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 V ++ G ++G + A++L G LL+ ++ E A A Sbjct: 3 KVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLADGYDAVLFGCSAWGM 62 Query: 67 SEKDVQTALALAKGKFGRV 85 + ++Q +F R+ Sbjct: 63 EDLEMQDDFLSLFEEFDRI 81 >3WJN-A nrPDB Length = 337 Score = 30.6 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 35/107 (32%), Gaps = 11/107 (10%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 +++GG + A L A AV + A + + DV E D++ Sbjct: 53 IVSGGGKRIRPMIAV-LA---ARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRR 108 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 A A FG A + + Q T +VL+V Sbjct: 109 GKATANAAFG-------NAASVLVGDFIYTRAFQMMTSLGSLKVLEV 148 >6BMQ-A nrPDB Length = 523 Score = 30.6 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 11/28 (39%) Query: 32 GQGASAVLLDLPNSGGEAQAKKLGNNCV 59 +GA V+ + A+ +G + Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKAL 412 >4B1B-A nrPDB Length = 542 Score = 30.6 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 21/50 (42%), Gaps = 1/50 (2%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 V+ GG G G+A+A+ GA +L D + +G CV Sbjct: 46 VVIGGGPG-GMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGC 94 >7REQ-A nrPDB Length = 727 Score = 30.6 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 26/91 (28%), Gaps = 3/91 (3%) Query: 17 GGASGLGLATAERLVGQGASAVLLDL--PNSGGEAQAKKLGNNCVFAPADVTSEKDVQTA 74 G G A G + L QA + + V + + A Sbjct: 608 GHDRGQ-KVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPA 666 Query: 75 LALAKGKFGRVDVAVNCAGIAVASKTYNLKK 105 L K GR D+ + G+ L+K Sbjct: 667 LRKELDKLGRPDILITVGGVIPEQDFDELRK 697 >3ZU2-A nrPDB Length = 422 Score = 30.2 bits (67), Expect = 0.80, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 43/137 (31%), Gaps = 31/137 (22%) Query: 11 LVAVITGGASGLGLATAERLVGQGASA----VLLDLPNSGGE-------------AQAKK 53 ++ G ++G GLA A G A V + P G+ A + Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 54 LGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED 113 G D S++ Q + K G+VD + + ++ T E Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYS--------LASPRRTHPKTGEV 175 Query: 114 FQRVL-----DVNLMGT 125 F L VNL G Sbjct: 176 FNSALKPIGNAVNLRGL 192 >3EXA-A nrPDB Length = 322 Score = 30.2 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 33/83 (39%), Gaps = 6/83 (7%) Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD--VNL 122 V +D+ T L + GR+ V G+ V + + G ED++ L+ VN Sbjct: 74 VADFQDLATPLITEIHERGRLPFLVGGTGLYVNAVIHQFNLGDIRADEDYRHELEAFVNS 133 Query: 123 MGTFNVIRLVAGEMGQNEPDQGG 145 G + + ++ + +P Sbjct: 134 YGV----QALHDKLSKIDPKAAA 152 >4XFD-A nrPDB Length = 283 Score = 30.2 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 44/254 (17%), Positives = 79/254 (31%), Gaps = 54/254 (21%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 GL ++ G + G+ TA L + + L G+ + + + E Sbjct: 50 SGLKTLVLGISGGVDSLTAGLLAQR----AVEQLREQTGDQAYRFIAVRLPYQVQ--QDE 103 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 D Q +LA + + G +V + L+ + V+ N+ Sbjct: 104 ADAQASLATIRADEEQT----VNIGPSVKALAEQLEALEGLEPAKSDFVIG-NIKARIR- 157 Query: 129 IRLVAGEMGQNEPDQGGQRGVIINT----ASVAAFEGQVGQAA------YSASKGGIVGM 178 M G + G++I T +V F + G A +K + + Sbjct: 158 -------MVAQYAIAGARGGLVIGTDHAAEAVMGFFTKFGDGACDLAPLSGLAKHQVRAL 210 Query: 179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ 238 + AP L+ +P L R G P E +H V Sbjct: 211 ARALG---APEN--------------LVEKIPTADLEDL--------RPGHPDEASHGVT 245 Query: 239 AIIENPFLNGEVIR 252 + FL+G+ +R Sbjct: 246 YAEIDAFLHGQPLR 259 >2YQ5-A nrPDB Length = 343 Score = 30.2 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 26/78 (33%), Gaps = 7/78 (8%) Query: 22 LGLATAERLVGQGASAVLLDLP-NSGGEAQAKKLGNNCVFAPADVTS-----EKDVQTAL 75 +G A AE GA + D+ N E + V AD+ S + + Sbjct: 159 IGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTYTDFDTVLKEADIVSLHTPLFPSTENMI 218 Query: 76 -ALAKGKFGRVDVAVNCA 92 + + +NCA Sbjct: 219 GEKQLKEMKKSAYLINCA 236 >4BKP-A nrPDB Length = 336 Score = 30.2 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 20/72 (27%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAP---ADVTSEKD 70 ++TGG+ +G A +++V GA G + VF AD+T Sbjct: 26 LVTGGSGLVGKAI-QKVVADGA----------------GLPGEDWVFVSSKDADLTDTAQ 68 Query: 71 VQTALALAKGKF 82 + + Sbjct: 69 TRALFEKVQPTH 80 >6BI4-A nrPDB Length = 346 Score = 30.2 bits (67), Expect = 0.89, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 56/167 (33%), Gaps = 22/167 (13%) Query: 14 VITGGASGLGLATAERLVG--QGASAVLLD-LPNSGGEAQAKKL--GNNCVFAPADVTSE 68 ++TGGA +G ++ + + D L SG K + N F ++ + Sbjct: 28 LVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGEIQNG 87 Query: 69 KDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 + ++ + V V VN A + ++ D N++GT + Sbjct: 88 ELLEHVIKERD-----VQVIVNFAAESHVDRSIENPIPF----------YDTNVIGTVTL 132 Query: 129 IRLV--AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG 173 + LV + + G + T + YS+SK Sbjct: 133 LELVKKYPHIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKA 179 >2WEK-A nrPDB Length = 341 Score = 30.2 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 1/47 (2%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG 55 +G ++T A G G A +L + V+ + A K LG Sbjct: 142 EGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEKSAFLKSLG 187 >1HSZ-A nrPDB Length = 374 Score = 30.2 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 32/90 (35%), Gaps = 13/90 (14%) Query: 12 VAVITGGA-------SGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 VA +T G+ G+GL+ GA+ ++ N A+AK+LG P D Sbjct: 186 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 245 Query: 65 VTSEKD------VQTALALAKGKFGRVDVA 88 + + GR+D Sbjct: 246 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTM 275 >3N58-A nrPDB Length = 464 Score = 30.2 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 34/107 (31%), Gaps = 26/107 (24%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGAS--------------------AVLLDLPNSGG 47 + G VAV+ G +G +A+ L G GA V LD S Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTA 303 Query: 48 EAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGI 94 + GN V + KD+ G G D + A + Sbjct: 304 DIVVTTTGNKDVITIDHMRKMKDMC-----IVGNIGHFDNEIQVAAL 345 >3VR3-A nrPDB Length = 600 Score = 30.2 bits (67), Expect = 0.96, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 21/63 (33%) Query: 23 GLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKF 82 G+ AE G ++ S +++ P D + + LA + Sbjct: 317 GITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERS 376 Query: 83 GRV 85 GRV Sbjct: 377 GRV 379 >4E0B-A nrPDB Length = 313 Score = 30.2 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 4/36 (11%) Query: 11 LVAVITGGASGLGLATAERLVG---QGASAVLLDLP 43 VAVI G A G+G A A L G+ L D+ Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIA 39 >1JAY-A nrPDB Length = 212 Score = 30.2 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 14/33 (42%), Gaps = 1/33 (3%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLP 43 VA++ GG LG A RL G V+ Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRR 33 >3LK7-A nrPDB Length = 451 Score = 30.2 bits (67), Expect = 0.98, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 18/57 (31%), Gaps = 1/57 (1%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 + + ++ G A G A A L GA + D A+ L + Sbjct: 6 TFENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVC 61 >1MLD-A nrPDB Length = 314 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 35/132 (26%), Gaps = 33/132 (25%) Query: 11 LVAVITGGASGLGLATAERLVGQG--ASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 VA + G + G+G + L + L D+ ++ G A AD++ Sbjct: 2 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVA-------------ADLSHI 47 Query: 69 KDVQTAL-----ALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 + T DV V AG+ + + N Sbjct: 48 ETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------------DDLFNTNAT 95 Query: 124 GTFNVIRLVAGE 135 + A Sbjct: 96 IVATLTAACAQH 107 >5GXF-A nrPDB Length = 330 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 12/36 (33%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE 48 ++TG A G+G L G + + Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >4EJ0-A nrPDB Length = 342 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 28/78 (35%), Gaps = 8/78 (10%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 ++TG A +G + L +G + ++ + + ++ D Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKN-------LVDCEIDDYLDKTE 68 Query: 74 ALA-LAKGKFGRVDVAVN 90 + A+G FG+V + Sbjct: 69 FVERFARGDFGKVRAVFH 86 >2GAS-A nrPDB Length = 307 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 24/87 (27%), Gaps = 14/87 (16%) Query: 14 VITGGASGLGLATAERLVGQGA-------SAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 +I G +G + G + P + E + D+ Sbjct: 6 LILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLGVILLEGDIN 65 Query: 67 SEKDVQTALALAKGKFGRVDVAVNCAG 93 + + A+ VD+ + AG Sbjct: 66 DHETLVKAIKQ-------VDIVICAAG 85 >3HZZ-A nrPDB Length = 467 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 12/89 (13%), Positives = 28/89 (31%), Gaps = 11/89 (12%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA----- 63 +G +I G + GLG + A + G + + + + + +G + Sbjct: 246 QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGYK 304 Query: 64 -----DVTSEKDVQTALALAKGKFGRVDV 87 K+ + + G D+ Sbjct: 305 FWKDEHTQDPKEWKRFGKRIRELTGGEDI 333 >4WLE-A nrPDB Length = 340 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 34/132 (25%), Gaps = 33/132 (25%) Query: 11 LVAVITGGASGLGLATAERLVGQG--ASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSE 68 VA + G + G+G + L + L D+ ++ G A AD++ Sbjct: 28 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVA-------------ADLSHI 73 Query: 69 KDVQTAL-----ALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123 + DV V AG+ + + N Sbjct: 74 ETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------------DDLFNTNAT 121 Query: 124 GTFNVIRLVAGE 135 + A Sbjct: 122 IVATLTAACAQH 133 >2BC1-A nrPDB Length = 490 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 20/35 (57%), Gaps = 2/35 (5%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNS 45 VAV+ GA +G+ AE +G VL+D+ ++ Sbjct: 196 RVAVV--GAGYIGVELAEAFQRKGKEVVLIDVVDT 228 >1HYE-A nrPDB Length = 313 Score = 29.8 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 34/98 (34%), Gaps = 1/98 (1%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 V +I G + +G ATA L + L+ + + + L + A A S+ + Sbjct: 2 KVTII-GASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60 Query: 71 VQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQT 108 + DV + +G+ + +T Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKT 98 >2Y6O-A nrPDB Length = 291 Score = 29.5 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 6/72 (8%) Query: 184 RDLAPIGIRVMT--IA--PGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 239 RDLA I V + + + +L PE ++P R P A+ Sbjct: 140 RDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPI--RWTAPEAIAYRKFT 197 Query: 240 IIENPFLNGEVI 251 + + G V+ Sbjct: 198 SASDVWSYGIVM 209 >4B4V-A nrPDB Length = 303 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 17/46 (36%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL 54 G AV+ G ++ LG A L+ A+ + K+ Sbjct: 178 AGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQA 223 >2GGS-A nrPDB Length = 273 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 39/118 (33%), Gaps = 27/118 (22%) Query: 14 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73 +ITG + LG+ + L + V+ +S + D+T ++ Sbjct: 4 LITGASGQLGIELSRLLSER--HEVIKVYNSSEIQ----------GGYKLDLTDFPRLED 51 Query: 74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 + R DV +N A + +E ++ +N +++R Sbjct: 52 FIIK-----KRPDVIINAAA---------MTDVDKCEIEK-EKAYKINAEAVRHIVRA 94 >3SC6-A nrPDB Length = 287 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 27/181 (14%), Positives = 47/181 (25%), Gaps = 55/181 (30%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 +ITG LG E L + D D+T+ VQ Sbjct: 8 VIITGANGQLGKQLQEELNPEEYDIYPFDKK------------------LLDITNISQVQ 49 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV 132 + R + ++CA ++ +N +G NV V Sbjct: 50 QVVQEI-----RPHIIIHCAAYTK----------VDQAEKERDLAYVINAIGARNV--AV 92 Query: 133 AGEMGQNEPDQGGQRGVIINTASVAAFEG----------QVGQAA-YSASKGGIVGMTLP 181 A ++ ++ ++ F+G Y ASK Sbjct: 93 ASQLV---------GAKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKE 143 Query: 182 I 182 + Sbjct: 144 L 144 >1CDO-A nrPDB Length = 374 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 32/104 (30%), Gaps = 13/104 (12%) Query: 23 GLATAERLVGQGAS-AVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81 GLA GA + +DL E VF D + D ++ K Sbjct: 205 GLAAVMGCHSAGAKRIIAVDLNPDKFEKAK-------VFGATDFVNPNDHSEPISQVLSK 257 Query: 82 F--GRVDV---AVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120 G VD V G+ + LK L + + DV Sbjct: 258 MTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDV 301 >6GBN-A nrPDB Length = 438 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 3/64 (4%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 + G VAV+ G +G +A L G GA ++ ++ A + V AD Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEIDP--ICALQAAMDGYEVKKMADAVK 273 Query: 68 EKDV 71 D+ Sbjct: 274 RADI 277 >1NHQ-A nrPDB Length = 447 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%), Gaps = 2/34 (5%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLPNS 45 V VI G+ +G+ AE G ++D+ + Sbjct: 152 VVVI--GSGYIGIEAAEAFAKAGKKVTVIDILDR 183 >3PII-A nrPDB Length = 339 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 33/88 (37%), Gaps = 18/88 (20%) Query: 15 ITGGASG-------LGL--ATAERLVGQ-GASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 +TG G +G A + G + V +D+ + E AK+LG AD Sbjct: 159 VTGAKPGEWVAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEKLE-LAKELG-------AD 210 Query: 65 VTSEKDVQTALALAKGKFGRVDVAVNCA 92 + + A K K G V AV A Sbjct: 211 LVVNPLKEDAAKFMKEKVGGVHAAVVTA 238 >4GBJ-A nrPDB Length = 297 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 25/75 (33%), Gaps = 13/75 (17%) Query: 22 LGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD-----------VTSEKD 70 LG AE L+ G V+ + S E KLG V D + + Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKAEPL-TKLGATVVENAIDAITPGGIVFSVLADDAA 74 Query: 71 VQTALA-LAKGKFGR 84 V+ + K G+ Sbjct: 75 VEELFSMELVEKLGK 89 >1IE3-A nrPDB Length = 312 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 38/128 (29%), Gaps = 26/128 (20%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 VA + G A G+G A A L Q SG E + D++ Sbjct: 2 KVA-VLGAAGGIGQALALLLKTQ---------LPSGSELSLYDIAPVTPGVAVDLSHIPT 51 Query: 71 VQTAL----ALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126 A DV + AG+A D + +VN Sbjct: 52 AVKIKGFSGEDATPALEGADVVLISAGVARKPGM------------DRSDLFNVNAGIVK 99 Query: 127 NVIRLVAG 134 N+++ VA Sbjct: 100 NLVQQVAK 107 >4PZE-A nrPDB Length = 284 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 29/190 (15%), Positives = 60/190 (31%), Gaps = 17/190 (8%) Query: 18 GASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNC-VFAPADVTSEKDVQTALA 76 GA +G A+ G + V++D+ ++ + + ++ + +E D +ALA Sbjct: 10 GAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEADKASALA 69 Query: 77 LA-----KGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 131 D+ + A K LK+ E ++ N + ++ +L Sbjct: 70 RIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGE--NVIIASN-TSSISITKL 126 Query: 132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 A + + A V G + + ++ L I Sbjct: 127 AAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSD---TTHAAVEALSK----QLGKYPI 179 Query: 192 RVMTIAPGLF 201 V +PG Sbjct: 180 TVKN-SPGFV 188 >1EDZ-A nrPDB Length = 320 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 16/39 (41%) Query: 6 RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPN 44 + G ++ + +G A L GA+ +D+ N Sbjct: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNN 211 >2OHJ-A nrPDB Length = 404 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 11/32 (34%), Gaps = 3/32 (9%) Query: 11 LVAVITGGASGLGLAT---AERLVGQGASAVL 39 A++ G G G AT E L G Sbjct: 344 RKALVFGSMGGNGGATGTMKELLAEAGFDVAC 375 >6CAU-A nrPDB Length = 472 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 16/44 (36%), Gaps = 4/44 (9%) Query: 21 GLGLA----TAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 60 G+G A AE L QG D+ S Q ++ G Sbjct: 19 GIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEENGIKVYI 62 >3H0K-A nrPDB Length = 178 Score = 29.1 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 19/48 (39%), Gaps = 2/48 (4%) Query: 11 LVAVITGGASGLGL-ATAERLVGQGASAVLLDLPNSGGEAQAKKLGNN 57 V +ITG G G A+ L +GA +++ + K G Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGER 47 >1YXY-A nrPDB Length = 234 Score = 29.1 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 29/59 (49%), Gaps = 7/59 (11%) Query: 138 QNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTI 196 + + + + G+I+ + + G+ YS + GGI+ + A++ +GIR ++ Sbjct: 7 KEKLMEQLKGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >2Q4W-A nrPDB Length = 524 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 22/68 (32%), Gaps = 1/68 (1%) Query: 16 TGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTAL 75 T A G G + + + +G V + + L A DV+ + L Sbjct: 88 TVAARGNGHSINGQAMAEGGLVVDMSTTAEN-HFEVGYLSGGDATAFVDVSGGALWEDVL 146 Query: 76 ALAKGKFG 83 ++G Sbjct: 147 KRCVSEYG 154 >4NFY-A nrPDB Length = 307 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 13/94 (13%), Positives = 29/94 (30%), Gaps = 15/94 (15%) Query: 11 LVAVIT------GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPAD 64 + VIT G+ L G V+++ + + + V +D Sbjct: 2 KIVVITEKPFAENAVKGI-REI---LEKAGHEVVMIEKYKKKEDVIERIKDADGVIVRSD 57 Query: 65 VTSEKDVQT-----ALALAKGKFGRVDVAVNCAG 93 E+ ++ + A + +D+ G Sbjct: 58 KIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQG 91 >3S8M-A nrPDB Length = 422 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 28/96 (29%), Gaps = 17/96 (17%) Query: 11 LVAVITGGASGLGLA----TAERLVGQGASA------------VLLDLPNSGGEAQAKKL 54 ++ G +SG GLA A ++ + AK Sbjct: 62 KKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAA 121 Query: 55 GNNCVFAPADVTSEKDVQTALALAKGKFGR-VDVAV 89 G D S+ + L K + G VD+ V Sbjct: 122 GLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVV 157 >3DC2-A nrPDB Length = 529 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 22/58 (37%), Gaps = 4/58 (6%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLD---LPNSGGEAQAKKLGNNCVFAPAD 64 G + G +G A+R+ GA V D P + + L + + A AD Sbjct: 142 GKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARAD 198 >4TSK-A nrPDB Length = 350 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 22/58 (37%), Gaps = 2/58 (3%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFA 61 + + + + G S G A A+ L G V+ P S A+A+ G + Sbjct: 11 SIQPLADKRIAVIGYGS-QGHAHAQNLRDSGFDVVIGLRPGSSW-AKAEADGFRVMAV 66 >3MMP-A nrPDB Length = 678 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 44/129 (34%), Gaps = 17/129 (13%) Query: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-------- 166 +VLD + G + ++ + + + G IN VAA EG V + Sbjct: 94 DKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIG 153 Query: 167 AYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSR 226 A+KG + IA +A P +++ E V Q+ + Sbjct: 154 VLVAAKGADEELVKHIAMHVAASK-------PEFIKPEDVSA--EVVEKEYQVQLDIAMQ 204 Query: 227 LGDPAEYAH 235 G P E A Sbjct: 205 SGKPKEIAE 213 >1X74-A nrPDB Length = 360 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 18 GASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALAL 77 G G A L GA V +D P+S + N AD+ S++ ++ AL L Sbjct: 14 AGIGPGPHAAMILGDLGADVVRIDRPSSVDGISRDAMLRNRRIVTADLKSDQGLELALKL 73 Query: 78 AKGKFGRVDVAV 89 DV + Sbjct: 74 IAKA----DVLI 81 >1DB3-A nrPDB Length = 372 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 22/76 (28%), Gaps = 8/76 (10%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL--------GNNCVFAP 62 VA+ITG G AE L+ +G + S + Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 63 ADVTSEKDVQTALALA 78 D++ ++ L Sbjct: 62 GDLSDTSNLTRILREV 77 >4A5O-A nrPDB Length = 286 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 20/42 (47%) Query: 1 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDL 42 +A+ + G+ AV+ G ++ +G A L+ G + + Sbjct: 152 LASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHR 193 >2JLA-A nrPDB Length = 558 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 26/101 (25%), Positives = 36/101 (35%), Gaps = 23/101 (22%) Query: 175 IVGMTLPIA---RD-LAPIGIRVMTIAPGLFGTPLL------------TSLPEKVCNFLA 218 + A + L G+R + IAPG TPL T E+ LA Sbjct: 5 VSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLA 64 Query: 219 ------SQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRL 253 S+ P + A+L A+IE L GE + L Sbjct: 65 LGLAKVSKQPVAVIVTSGTAVANLYPALIEAG-LTGEKLIL 104 >1P0F-A nrPDB Length = 373 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Query: 18 GASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALAL 77 G G+G + GAS ++ + +A +LG P D + + Sbjct: 199 GLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKP--IYEVI-- 254 Query: 78 AKGKFGRVDVAVNCAG 93 + G VD AV CAG Sbjct: 255 CEKTNGGVDYAVECAG 270 >5BN5-A nrPDB Length = 570 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 23/67 (34%) Query: 22 LGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81 LG E QG S V+ S +++ + P++ + LA + Sbjct: 300 LGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYER 359 Query: 82 FGRVDVA 88 GRV Sbjct: 360 SGRVRTL 366 >5KXJ-A nrPDB Length = 557 Score = 28.3 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 31/102 (30%), Gaps = 16/102 (15%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQ 72 +I G + GL+ A RL + VL P S G + G VF D + Sbjct: 11 VLIIGSGAA-GLSLALRLAEKHKVIVLSKGPVSEGSTFYAQGGIAAVFDETD-----SIA 64 Query: 73 TALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDF 114 + + D + AGI T + Sbjct: 65 SHVE---------DTLIAGAGIC-DRHAVEFVASNARTCVQW 96 >5UZH-A nrPDB Length = 345 Score = 28.3 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 8/77 (10%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNNCVFAPA------ 63 VA+ITG G AE L+ +G ++ +S + + L + A Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLLY 61 Query: 64 -DVTSEKDVQTALALAK 79 D+T ++ + +A K Sbjct: 62 GDLTDTGNLISIIAKIK 78 >1QQV-A nrPDB Length = 67 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 18/66 (27%), Gaps = 11/66 (16%) Query: 84 RVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLV---AGEMGQNE 140 +DV VN A + +K + EDF F + R Q Sbjct: 8 PLDVLVNTAAEDLPRGVDPSRKENHLSDEDF--------KAVFGMTRSAFANLPLWKQQN 59 Query: 141 PDQGGQ 146 + Sbjct: 60 LKKEKG 65 >1KGZ-A nrPDB Length = 345 Score = 28.3 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 12/33 (36%) Query: 212 KVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 244 + A+ + R P E A A++ + Sbjct: 44 EDSQLAAALISMKMRGERPEEIAGAASALLADA 76 >4BKO-A nrPDB Length = 417 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 28/95 (29%), Gaps = 16/95 (16%) Query: 11 LVAVITGGASGLGLATAER-------------LVGQGASA---VLLDLPNSGGEAQAKKL 54 ++ G ++G GLA A A ++ +A Sbjct: 62 KKVLVIGASTGYGLAARIAAAFGAGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAAR 121 Query: 55 GNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAV 89 G D S++ + + G+VD+ V Sbjct: 122 GLQATSVNGDAFSDEIKHKTIDAIRRDLGQVDLVV 156 >2X86-A nrPDB Length = 357 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 32/80 (40%), Gaps = 5/80 (6%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKD 70 + ++TGGA +G + L +G + D+ K N AD ++D Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKG----ITDILVVDNLKDGTKFVNLVDLNIADYMDKED 102 Query: 71 VQTALALAKGKFGRVDVAVN 90 + +A +FG V+ + Sbjct: 103 FLIQI-MAGEEFGDVEAIFH 121 >2R5U-A nrPDB Length = 200 Score = 28.3 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 22/72 (30%), Gaps = 2/72 (2%) Query: 24 LATAERLVGQGASAVLLDLPNSGGE--AQAKKLGNNCVFAPADVTSEKDVQTALALAKGK 81 A RLV G V + G A+ ++ AD +D L + Sbjct: 129 KALLRRLVEAGTRVVQYGYAGAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPT 188 Query: 82 FGRVDVAVNCAG 93 +D + G Sbjct: 189 MDEIDAIASSGG 200 >4B4O-A nrPDB Length = 298 Score = 28.3 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 18/47 (38%) Query: 13 AVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV 59 ++ GG +G A + L +G L+ G +L + + Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGL 49 >5TC4-A nrPDB Length = 316 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 33/110 (30%), Gaps = 21/110 (19%) Query: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEK 69 G V+ G + +G+ A L GA ++ G + + Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH---------------ERPGGDATVTISH----- 198 Query: 70 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 119 T K D+ ++ AGI +K+G RV D Sbjct: 199 -RYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHD 247 >3X2F-A nrPDB Length = 411 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 22/82 (26%), Gaps = 11/82 (13%) Query: 8 VKGLVAVITGGASG-LGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 66 V G V+ G G A R G GA ++ ++ + V Sbjct: 195 VAGKNVVV--AGYGWCGRGIALRAAGLGARVIVTEVDPVKA--------VEAIMDGFTVM 244 Query: 67 SEKDVQTALALAKGKFGRVDVA 88 K+ G DV Sbjct: 245 PMKEAVKIADFVITASGNTDVL 266 >3DQQ-A nrPDB Length = 421 Score = 27.9 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 21/58 (36%) Query: 153 TASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLP 210 TAS A Q + + + + +A LA GI +A G + SL Sbjct: 316 TASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGGETSGVVTQSLG 373 >6APE-A nrPDB Length = 298 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 16/34 (47%) Query: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDL 42 KG I G ++ +G + ++ GAS + + Sbjct: 169 KGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHI 202 >5ZJN-A nrPDB Length = 253 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 4/61 (6%) Query: 27 AERLVGQGASAVLLDLPN----SGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKF 82 + L GA+ + D N E A+ + N FA AD ++ +D A + Sbjct: 110 VDGLANAGATVIAFDATNRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIV 169 Query: 83 G 83 G Sbjct: 170 G 170 >1UUF-A nrPDB Length = 369 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 19/61 (31%), Gaps = 6/61 (9%) Query: 21 GLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKG 80 G+ LA A GA V + EA AK LG + V + + Sbjct: 210 GIKLAHA-----MGAHVVAFTTSEAKREA-AKALGADEVVNSRNADEMAAHLKSFDFILN 263 Query: 81 K 81 Sbjct: 264 T 264 >3M2P-A nrPDB Length = 311 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 35/121 (28%), Gaps = 18/121 (14%) Query: 11 LVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF-APADVTSEK 69 +A +TGG LG E + G + ++L +GN + V+ Sbjct: 4 KIA-VTGGTGFLGQYVVESIKNDGNTPIILTRS----------IGNKAINDYEYRVSDY- 51 Query: 70 DVQTALALAKGKFGRVDVAVNCAGI-AVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128 L + VD V+ A K + T + + N+ Sbjct: 52 ----TLEDLINQLNDVDAVVHLAATRGSQGKISEFHDNEILTQNLYDACYENNISNIVYA 107 Query: 129 I 129 Sbjct: 108 S 108 >2IUU-A nrPDB Length = 491 Score = 27.9 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLA 218 I + +AR LA I +RV+ + PG T + +P + + Sbjct: 136 ISNLAKDLARSLAVISVRVVEVIPG--KTTVGIEIPNEDRQMVR 177 >4Y4N-A nrPDB Length = 286 Score = 27.9 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 2/32 (6%) Query: 12 VAVITGGASGLGLATAERLVGQGASAVLLDLP 43 VA++ GG SGL A + +G V+L+ Sbjct: 55 VAIVGGGPSGL--TAARYIAKEGYKVVVLERH 84 >4W5U-B nrPDB Length = 408 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 25/83 (30%), Gaps = 5/83 (6%) Query: 56 NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE--- 112 N D + + +A + FG D V A A + ++ Sbjct: 185 PNACGLTCDSSGPDAFRNLMAALRSTFG--DELVTAAVTADGTPGGKIEATDYAGAAQYV 242 Query: 113 DFQRVLDVNLMGTFNVIRLVAGE 135 D+ V+ + G ++ A Sbjct: 243 DWYNVMTYDFFGAWDAQGPTAPH 265 >5T57-A nrPDB Length = 296 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%), Gaps = 1/72 (1%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67 +K +A+ G +G+ A+ L+ +++ G + +LG CV A + + Sbjct: 21 MKEKIALF-GAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDN 79 Query: 68 EKDVQTALALAK 79 V A+ Sbjct: 80 VDVVILAVPDTI 91 >4R16-A nrPDB Length = 418 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 10/24 (41%) Query: 22 LGLATAERLVGQGASAVLLDLPNS 45 +GL TA G V D+ + Sbjct: 11 IGLPTAIMFASSGYDVVGYDIRSE 34 >2IUT-A nrPDB Length = 574 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLA 218 I + +AR LA I +RV+ + PG T + +P + + Sbjct: 136 ISNLAKDLARSLAVISVRVVEVIPG--KTTVGIEIPNEDRQMVR 177 >4P2F-A nrPDB Length = 273 Score = 27.5 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 48/159 (30%), Gaps = 19/159 (11%) Query: 24 LATAERLVGQGASAVLLDLPNSGGEAQAKKLG---NNCVFAPAD-VTSEKDVQTALALAK 79 + AERL + ++ D + A +G APAD V + +A Sbjct: 59 ASIAERL-KEPERNIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELV 117 Query: 80 GKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF------------- 126 + G + V+ V S + T L DF + N+ Sbjct: 118 DQHGLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDM-TNVAAQLKDPRGNPVPLRVG 176 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQ 165 V + + + G +N AS VGQ Sbjct: 177 LATGPVVAGVVGSRRFRYDVWGDAVNVASRMESTDSVGQ 215 >4D3S-A nrPDB Length = 293 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%) Query: 22 LGLATAERLVGQGASAVLLDLPNSGGEAQAKK 53 +G A A L+ G + + + EA A++ Sbjct: 19 MGQAMAGALLEAGYELTVWNRTKAKAEALAER 50 >3JTJ-A nrPDB Length = 253 Score = 27.5 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 23/68 (33%), Gaps = 5/68 (7%) Query: 28 ERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFG--RV 85 ER + GA V++ + + G AD + LA +G Sbjct: 38 ERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRAD---HQSGTERLAEVIEHYGFADD 94 Query: 86 DVAVNCAG 93 D+ VN G Sbjct: 95 DIIVNVQG 102 >2D0I-A nrPDB Length = 333 Score = 27.1 bits (59), Expect = 6.9, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 23/65 (35%), Gaps = 4/65 (6%) Query: 4 ACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNS---GGEAQAKKLGNNCVF 60 S+ G I G +G A A RL+ G E +A+ + + + Sbjct: 140 RIESLYGKKVGILG-MGAIGKAIARRLIPFGVKLYYWSRHRKVNVEKELKARYMDIDELL 198 Query: 61 APADV 65 +D+ Sbjct: 199 EKSDI 203 >4A26-A nrPDB Length = 300 Score = 27.1 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 20/41 (48%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE 48 + G AV+ G ++ +G A L+ + A+ ++ S + Sbjct: 163 MAGKRAVVLGRSNIVGAPVAALLMKENATVTIVHSGTSTED 203 >3IGS-A nrPDB Length = 232 Score = 27.1 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 27 AERLVGQGASAVLLDLPNS----GGEAQAKKLGNNCVFAPADVTSEKD 70 + L GA+ + +D EA ++ ++ + AD +S D Sbjct: 94 VDALAQAGAAIIAVDGTARQRPVAVEALLARIHHHHLLTMADCSSVDD 141 >4WEQ-A nrPDB Length = 341 Score = 27.1 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 11/45 (24%), Gaps = 2/45 (4%) Query: 22 LGLATAERLVGQGASAVLLDLPNSGGE--AQAKKLGNNCVFAPAD 64 LG A +L G + E G + D Sbjct: 172 LGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGRTD 216 >2DQ4-A nrPDB Length = 343 Score = 27.1 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCV 59 V G +ITG +GL A + GA +L+ PN A A+ + V Sbjct: 163 VSGKSVLITGAGP-IGLMAAMVVRASGAGPILVSDPNPYRLAFARPYADRLV 213 >4PC7-C nrPDB Length = 282 Score = 27.1 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 44/129 (34%), Gaps = 17/129 (13%) Query: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-------- 166 +VLD + G + ++ + + + G IN VAA EG V + Sbjct: 93 DKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIG 152 Query: 167 AYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSR 226 A+KG + IA +A P +++ E V Q+ + Sbjct: 153 VLVAAKGADEELVKHIAMHVAASK-------PEFIKPEDVSA--EVVEKEYQVQLDIAMQ 203 Query: 227 LGDPAEYAH 235 G P E A Sbjct: 204 SGKPKEIAE 212 >4AP9-A nrPDB Length = 201 Score = 27.1 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%) Query: 24 LATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 E L +G VL+ K+LG+ + A Sbjct: 85 RELVETLREKGFKVVLISGSFEEVLEPFKELGDEFMANRA 124 >3IC6-A nrPDB Length = 223 Score = 27.1 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 38/116 (32%), Gaps = 23/116 (19%) Query: 135 EMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVM 194 M +P G I + + +G AA + G+ +T Sbjct: 3 AMTALKPALPDYLGNIRIILTRTSHPANIGSAARAMKTMGLHRLT--------------- 47 Query: 195 TIAPGLFGTPLLTS----LPEKVCNFLASQVPFPSRLGDPAEY---AHLVQAIIEN 243 + P L TP+ + P+ V +F + F G A+ A +V + E Sbjct: 48 IVTPNLMATPMTENPPVFNPDDVQSFALPEESFILASG-AADVLHNAEIVATLDEA 102 >3HDH-A nrPDB Length = 302 Score = 27.1 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 13/32 (40%), Gaps = 1/32 (3%) Query: 15 ITGGASGL-GLATAERLVGQGASAVLLDLPNS 45 +T GL G A+ G + VL+D Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 49 >6MVR-A nrPDB Length = 767 Score = 26.8 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 11/92 (11%) Query: 9 KGLVAVITG-GASG--LGLATAERLVGQGASAVLLDLPNSGG---EAQAKKLGNNCVFAP 62 G+V ++TG GA G + A +++ G++AV + + +A + +LG + Sbjct: 212 AGVVNIVTGDGAVGEMIVTAQVDKVAFTGSTAVGRRIREATAGTGKALSLELGGKGPYVV 271 Query: 63 ADVTS-EKDVQTALALAKGKFGRVDVAVNCAG 93 D + V+ + G+ V CAG Sbjct: 272 CDDADIDSAVEGLVDAIWFNQGQ----VCCAG 299 >5Y77-A nrPDB Length = 473 Score = 26.8 bits (58), Expect = 9.1, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 17/48 (35%), Gaps = 3/48 (6%) Query: 16 TGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA 63 TG G + L +GA A+ L A+A + V P Sbjct: 47 TGAR---GRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPG 91 >4P2M-A nrPDB Length = 234 Score = 26.8 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 47/159 (29%), Gaps = 19/159 (11%) Query: 24 LATAERLVGQGASAVLLDLPNSGGEAQAKKLG---NNCVFAPAD-VTSEKDVQTALALAK 79 + AERL + ++ D + A +G APAD V + +A Sbjct: 20 ASIAERL-KEPERNIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELV 78 Query: 80 GKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF------------- 126 + G + V+ V S + T L DF + N+ Sbjct: 79 DQHGLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDM-TNVAAQLKDPRGNPVPLRVG 137 Query: 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQ 165 V + + G +N AS VGQ Sbjct: 138 LATGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGQ 176 >5UOG-A nrPDB Length = 344 Score = 26.8 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 16/41 (39%), Gaps = 1/41 (2%) Query: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGG 47 S++G + G +GLA A RL G S G Sbjct: 161 SLRGRTVGLFGLGR-IGLAIARRLEAFGVSIAYHTRTPREG 200 >4Z6K-A nrPDB Length = 346 Score = 26.8 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 20/69 (28%), Gaps = 8/69 (11%) Query: 24 LATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFG 83 LA A++L GA + E K++G V+ A A Sbjct: 201 LAFAKKL---GAKVTVNAKNTDPAEYLQKEIGGAHGALVTAVS-----AKAFDQALSMLR 252 Query: 84 RVDVAVNCA 92 R V Sbjct: 253 RGGTLVCNG 261 >3DDL-A nrPDB Length = 273 Score = 26.8 bits (58), Expect = 10.0, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 12/28 (42%) Query: 23 GLATAERLVGQGASAVLLDLPNSGGEAQ 50 G A+ L G ++ ++ + E + Sbjct: 231 GYTIADVLAKAGYGVLIYNIAKAKSEEE 258 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.153 0.452 Lambda K H 0.267 0.0471 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,792,386 Number of Sequences: 36641 Number of extensions: 555125 Number of successful extensions: 3641 Number of sequences better than 10.0: 414 Number of HSP's better than 10.0 without gapping: 394 Number of HSP's successfully gapped in prelim test: 198 Number of HSP's that attempted gapping in prelim test: 2221 Number of HSP's gapped (non-prelim): 635 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.1 bits)