BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q99685 (303 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3JWE-A nrPDB 624 e-179 6EIC-C nrPDB 169 1e-42 4ZWN-A nrPDB 76 2e-14 4FBL-A nrPDB 46 2e-05 1A88-A nrPDB 45 5e-05 1A8S-A nrPDB 42 2e-04 3C5W-P nrPDB 41 5e-04 1XRN-A nrPDB 36 0.021 4HTA-A nrPDB 35 0.033 1A8Q-A nrPDB 35 0.033 2Y6V-A nrPDB 35 0.042 2OCI-A nrPDB 34 0.091 3R4T-A nrPDB 33 0.11 1UWC-A nrPDB 33 0.11 1UFO-A nrPDB 33 0.12 2RON-A nrPDB 32 0.23 3WYD-A nrPDB 32 0.27 2E3J-A nrPDB 32 0.47 1DT3-A nrPDB 32 0.48 6CHS-A nrPDB 31 0.69 4S3P-A nrPDB 31 0.76 6BJE-A nrPDB 30 0.91 3FCX-A nrPDB 30 0.92 5MRJ-A nrPDB 30 0.93 4TGL-A nrPDB 30 0.93 4IH4-A nrPDB 30 1.0 6QPR-A nrPDB 30 1.1 4C2T-A nrPDB 30 1.3 4C2U-A nrPDB 30 1.3 6AP7-A nrPDB 30 1.4 4YCZ-A nrPDB 30 1.7 3V1K-A nrPDB 30 1.8 4Q2T-A nrPDB 29 2.2 1LGY-A nrPDB 29 2.5 3O0D-A nrPDB 29 2.6 3I4J-A nrPDB 29 2.8 5GW8-A nrPDB 28 3.4 3M5U-A nrPDB 28 4.4 4XJV-A nrPDB 28 4.5 5CH8-A nrPDB 28 4.6 2WUG-A nrPDB 28 6.0 3LS2-A nrPDB 28 6.1 5XY3-c nrPDB 28 6.8 3E4D-A nrPDB 28 7.0 3NGM-A nrPDB 27 8.2 >3JWE-A nrPDB Length = 320 Score = 624 bits (1608), Expect = e-179, Method: Compositional matrix adjust. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE 60 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE Sbjct: 18 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE 77 Query: 61 LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG 120 LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG Sbjct: 78 LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG 137 Query: 121 HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID 180 HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID Sbjct: 138 HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID 197 Query: 181 SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR 240 SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR Sbjct: 198 SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR 257 Query: 241 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA 300 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA Sbjct: 258 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA 317 Query: 301 SPP 303 SPP Sbjct: 318 SPP 320 >6EIC-C nrPDB Length = 279 Score = 169 bits (429), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/259 (36%), Positives = 143/259 (55%), Gaps = 3/259 (1%) Query: 35 WKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFH 94 W P P+A++ ++HG GEH+ RY+ +A+ L L+ +A DH GHG+S G+R++V D Sbjct: 23 WTPDTAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRDIS 82 Query: 95 VFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPE 154 + D V ++YPG +LGHSMGG I ERP ++ MVL +P V A + Sbjct: 83 EYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAAQ-D 141 Query: 155 SATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLL 214 + +AAK+L +V+P L + +D + +SR+ V YN+DPL+ + G LL Sbjct: 142 LVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNTDPLVHHGRVPAGIGRALL 201 Query: 215 NAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKE 274 + R P LT P L+L G+ DRL +G+ L+E S D LK Y G YH + E Sbjct: 202 QVGETMPRRAPALTAPLLVLHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNE 261 Query: 275 LPEVTNSVFHEINMWVSQR 293 PE N V ++ W+++R Sbjct: 262 -PE-RNQVLDDVVAWLTER 278 >4ZWN-A nrPDB Length = 334 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/312 (23%), Positives = 130/312 (41%), Gaps = 29/312 (9%) Query: 7 PRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLM 66 P + ++P + A Y+F T + + + HG GE++ L L Sbjct: 26 PYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLS 85 Query: 67 GLDLLVFAHDHVGHGQSEGERM--VVSDFHVFVRDVLQHVDS--MQKDYPGLPVFLLGHS 122 F D G G + R V ++HVF D+ V+ + G+P+F+ GHS Sbjct: 86 LNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF-NDLEHFVEKNLSECKAKGIPLFMWGHS 144 Query: 123 MGGAIAILTAAE--RPGHFAGMVLISPLVLANPESATTFKV-LAAKVLNLVLPNLSLGP- 178 MGG I + A + +G + PL++ +P + + A +L P + + Sbjct: 145 MGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFSPRVRIDTG 204 Query: 179 IDSSVLSRNKTEVDIYNSDPL-------------ICRAGLKVCFGIQLLNAVSRVERALP 225 +D ++ +K SDP+ + G K+ N + +++ Sbjct: 205 LDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKL-----YKNENNYIQKNFA 259 Query: 226 KLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH-VLHKELPEVTNSVFH 284 K P +++ G D + D KG+ + S DK LK+Y GA H + E +V N+VF+ Sbjct: 260 K-DKPVIIMHGQDDTINDPKGSEKFIRDCPSADKELKLYPGARHSIFSLETDKVFNTVFN 318 Query: 285 EINMWVSQRTAT 296 ++ W+ + T T Sbjct: 319 DMKQWLDKHTTT 330 >4FBL-A nrPDB Length = 281 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/227 (25%), Positives = 92/227 (40%), Gaps = 21/227 (9%) Query: 45 IFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHV 104 + VSHG LA V GHG + E M S + D++ + Sbjct: 54 VLVSHGFTGSPQSMRFLAEGFARAGYTVATPRLTGHGTTPAE-MAASTASDWTADIVAAM 112 Query: 105 DSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLI-SPLVLANPESATTFKVLA 163 +++ L F+ G SMGGA+ + A + P FAG++ I + L + +P+ LA Sbjct: 113 RWLEERCDVL--FMTGLSMGGALTVWAAGQFPERFAGIMPINAALRMESPD-------LA 163 Query: 164 AKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERA 223 A N P L I S + + E+ + P+ +K L+ + E Sbjct: 164 ALAFNPDAP-AELPGIGSDIKAEGVKEL----AYPVTPVPAIK-----HLITIGAVAEML 213 Query: 224 LPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHV 270 LP++ P L++Q D + L+ S +K L E +YHV Sbjct: 214 LPRVKCPALIIQSREDHVVPPHNGELIYNGIGSTEKELLWLENSYHV 260 >1A88-A nrPDB Length = 275 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 69/286 (24%), Positives = 111/286 (38%), Gaps = 49/286 (17%) Query: 22 LVNADGQYLFCRYWKP-TGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGH 80 + +DG +F + W P G P + HG + ++ + V AHD GH Sbjct: 3 VTTSDGTNIFYKDWGPRDGLP---VVFHHGWPLSADDWDNQMLFFLSHGYRVIAHDRRGH 59 Query: 81 GQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGHF 139 G+S+ + D + DV +++ D G +GHS GG +A A PG Sbjct: 60 GRSD-QPSTGHDMDTYAADVAALTEAL--DLRG--AVHIGHSTGGGEVARYVARAEPGRV 114 Query: 140 AGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDI------ 193 A VL+S + +S T L +V + L+ +R + +D+ Sbjct: 115 AKAVLVSAVPPVMVKSDTNPDGLPLEVFDEFRAALA--------ANRAQFYIDVPSGPFY 166 Query: 194 -YNSDPLICRAGLKVCFGIQ-----------LLNAVSRVE--RALPKLTVPFLLLQGSAD 239 +N + GL + +Q + A S + L ++ VP L+ G+ D Sbjct: 167 GFNREGATVSQGLIDHWWLQGMMGAANAHYECIAAFSETDFTDDLKRIDVPVLVAHGTDD 226 Query: 240 RL-----CDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTN 280 ++ K A LL + TLK YEG H + PEV N Sbjct: 227 QVVPYADAAPKSAELL------ANATLKSYEGLPHGMLSTHPEVLN 266 >1A8S-A nrPDB Length = 273 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 71/272 (26%), Positives = 111/272 (40%), Gaps = 53/272 (19%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 Y+K G+ + ++F SHG ++ +E L V AHD GHG+S + +D Sbjct: 12 YYKDWGSGQPIVF-SHGWPLNADSWESQMIFLAAQGYRVIAHDRRGHGRSS-QPWSGNDM 69 Query: 94 HVFVRDVLQHVDSMQ-KDYPGLPVFLLGHSMGGA-IAILTAAERPGHFAGMVLIS---PL 148 + D+ Q ++ + +D L G S GG +A A LIS PL Sbjct: 70 DTYADDLAQLIEHLDLRD-----AVLFGFSTGGGEVARYIGRHGTARVAKAGLISAVPPL 124 Query: 149 VL---ANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDI-------YNSDP 198 +L ANP L +V + G +S+ R++ D+ +N Sbjct: 125 MLKTEANPGG------LPMEVFD--------GIRQASLADRSQLYKDLASGPFFGFNQPG 170 Query: 199 LICRAGLKVCFGIQ-----------LLNAVSRVE--RALPKLTVPFLLLQGSADRLCDSK 245 AG+ F +Q + A S + L K+ VP L++ G AD++ + Sbjct: 171 AKSSAGMVDWFWLQGMAAGHKNAYDCIKAFSETDFTEDLKKIDVPTLVVHGDADQVVPIE 230 Query: 246 GAYLLMELAKSQDKTLKIYEGAYHVL---HKE 274 A + A + TLKIY GA H L HK+ Sbjct: 231 -ASGIASAALVKGSTLKIYSGAPHGLTDTHKD 261 >3C5W-P nrPDB Length = 310 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%) Query: 24 NADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDHVGHGQ 82 N G+ F Y +G+ ++ + HG G + + A ++ + + A D HG+ Sbjct: 26 NETGKDTFRVY--KSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGE 83 Query: 83 SEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAA 133 ++ + +DV V++M D P P+ L+GH+MGGAIA+ TA+ Sbjct: 84 TKVKNPEDLSAETMAKDVGNVVEAMYGDLPP-PIMLIGHAMGGAIAVHTAS 133 >1XRN-A nrPDB Length = 293 Score = 35.8 bits (81), Expect = 0.021, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 12/130 (9%) Query: 19 LPHLVNADGQYLFCRYWKPTGTP--KALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHD 76 + + +G Y+ Y+K P KA + HG S Y R + + V +D Sbjct: 6 IENYAKVNGIYI---YYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYD 62 Query: 77 HVGHGQSE--GERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAE 134 G G+SE + D+ V + L+ K + VFL+G S GGA+A+ A + Sbjct: 63 QFGCGRSEEPDQSKFTIDYGVEEAEALR-----SKLFGNEKVFLMGSSYGGALALAYAVK 117 Query: 135 RPGHFAGMVL 144 H G+++ Sbjct: 118 YQDHLKGLIV 127 >4HTA-A nrPDB Length = 288 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 8/114 (7%) Query: 36 KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVV---SD 92 K G+ +A I + HG G ++ L L+ D V +D++G G + + S+ Sbjct: 29 KVIGSGEATIVLGHGFGTDQSVWKHLVPHLVD-DYRVVLYDNMGAGTTNPDYFDFDRYSN 87 Query: 93 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS 146 + D++ ++ ++ + +GHS+ I +L + RP F+ +V+IS Sbjct: 88 LEGYSFDLIAILEDLKIE----SCIFVGHSVSAMIGVLASLNRPDLFSKIVMIS 137 >1A8Q-A nrPDB Length = 274 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 64/266 (24%), Positives = 108/266 (40%), Gaps = 30/266 (11%) Query: 20 PHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVG 79 P DG +F + W G + ++F+ HG + +++ + ++ AHD G Sbjct: 1 PICTTRDGVEIFYKDW---GQGRPVVFI-HGWPLNGDAWQDQLKAVVDAGYRGIAHDRRG 56 Query: 80 HGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGH 138 HG S DF F D+ + + V L+ HSMGG +A G Sbjct: 57 HGHST-PVWDGYDFDTFADDLNDLLTDLDL----RDVTLVAHSMGGGELARYVGRHGTGR 111 Query: 139 FAGMVLIS---PLVL---ANPESATTFKVLAAKVLNLVLPNLSLGPIDSS--VLSRNK-- 188 VL+S P+++ NP+ A K N VL S D++ S N+ Sbjct: 112 LRSAVLLSAIPPVMIKSDKNPDGVPDEVFDALK--NGVLTERSQFWKDTAEGFFSANRPG 169 Query: 189 TEVDIYNSDPLICRA-GLKVCFGIQLLNAVSRVE--RALPKLTVPFLLLQGSADRLC--D 243 +V N D A + G++ ++A + L K +P L++ G D++ D Sbjct: 170 NKVTQGNKDAFWYMAMAQTIEGGVRCVDAFGYTDFTEDLKKFDIPTLVVHGDDDQVVPID 229 Query: 244 SKGAYLLMELAKSQDKTLKIYEGAYH 269 + G + ++ LK+YEG+ H Sbjct: 230 ATGRKSAQIIPNAE---LKVYEGSSH 252 >2Y6V-A nrPDB Length = 398 Score = 35.0 bits (79), Expect = 0.042, Method: Compositional matrix adjust. Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 24/132 (18%) Query: 38 TGTPKALIFVSHGAGEHSGRYEELARMLMGLDL-------LVFAHDHVGHGQS--EGERM 88 T T L+F+ HG+G +E L+ D V D V HG S Sbjct: 49 TATRLNLVFL-HGSGMSKVVWEYYLPRLVAADAEGNYAIDKVLLIDQVNHGDSAVRNRGR 107 Query: 89 VVSDFHVF--VRDVLQ-------HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHF 139 + ++F+ RDVL+ +DS +P L V ++GHSMGG A+ +P F Sbjct: 108 LGTNFNWIDGARDVLKIATCELGSIDS----HPALNV-VIGHSMGGFQALACDVLQPNLF 162 Query: 140 AGMVLISPLVLA 151 ++LI P+V+ Sbjct: 163 HLLILIEPVVIT 174 >2OCI-A nrPDB Length = 254 Score = 33.9 bits (76), Expect = 0.091, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 67/175 (38%), Gaps = 24/175 (13%) Query: 72 VFAHDHVGHGQSEG-ERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAIL 130 V A D G+G S +R +DF F RD VD M K V LLG S GG A++ Sbjct: 54 VVAWDPRGYGHSRPPDRDFPADF--FERDAKDAVDLM-KALKFKKVSLLGWSDGGITALI 110 Query: 131 TAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLS-RNKT 189 AA+ P + MV+ E + ++ G D S S R + Sbjct: 111 AAAKYPSYIHKMVIWGANAYVTDEDSMIYE----------------GIRDVSKWSERTRK 154 Query: 190 EVDIYNSDPLICRAGLKVCFGIQLLNAV---SRVERALPKLTVPFLLLQGSADRL 241 ++ R K GI+ + + LP++ P L++ G D L Sbjct: 155 PLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPL 209 >3R4T-A nrPDB Length = 467 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query: 194 YNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLL-LQGSADRLCD--SKGAYLL 250 + +P+ C A L I+ V R R + +L + LL LQ + DRL D +GA + Sbjct: 343 FGGNPVACAAALATIETIERDGMVERA-RQIERLVMDRLLRLQAADDRLGDVRGRGAMIA 401 Query: 251 MELAKS 256 MEL KS Sbjct: 402 MELVKS 407 >1UWC-A nrPDB Length = 261 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 38/156 (24%), Positives = 62/156 (39%), Gaps = 34/156 (21%) Query: 40 TPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRD 99 T K +I V G G + + L D L +D HG +++ Sbjct: 57 TSKEIITVFRGTGSDTNLQLDTNYTLTPFDTLPQCNDCEVHG----------GYYIGWIS 106 Query: 100 VLQHVDSMQKD----YPGLPVFLLGHSMGGAIAILTAAE----------------RPGHF 139 V V+S+ K YP + + GHS+G ++A LTAA+ R G+ Sbjct: 107 VQDQVESLVKQQASQYPDYALTVTGHSLGASMAALTAAQLSATYDNVRLYTFGEPRSGNQ 166 Query: 140 A-GMVLISPLVLANPESATTFKVLAAKVLNLVLPNL 174 A + +++PE+ F+V + N +PNL Sbjct: 167 AFASYMNDAFQVSSPETTQYFRVTHS---NDGIPNL 199 >1UFO-A nrPDB Length = 238 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 17/108 (15%) Query: 40 TPKALIFVSHGAGEHSGRYEELARMLMGL---DLLVFAHDHVGHGQSEGE-------RMV 89 PKAL+ HG G E + +L G L+ A D HG+ EG R V Sbjct: 22 APKALLLALHGL---QGSKEHILALLPGYAERGFLLLAFDAPRHGEREGPPPSSKSPRYV 78 Query: 90 VSDFHV---FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAE 134 + V F + + + ++ + GLP+FL G S+G +A L AE Sbjct: 79 EEVYRVALGFKEEARRVAEEAERRF-GLPLFLAGGSLGAFVAHLLLAE 125 >2RON-A nrPDB Length = 242 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 15/103 (14%) Query: 51 AGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKD 110 AG +S + L L G + + A + GHG ++ + D+ + D +++ Sbjct: 22 AGGYSASFRPLHAFLQG-ECEMLAAEPPGHGTNQTSA---------IEDLEELTDLYKQE 71 Query: 111 Y---PGLPVFLLGHSMGGAIAILTAA--ERPGHFAGMVLISPL 148 P P L GHSMGG I A ER G F V+IS + Sbjct: 72 LNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAI 114 >3WYD-A nrPDB Length = 228 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 6/61 (9%) Query: 98 RDVLQHVDSMQKDYPGLP--VFLLGHSMGGAIAILTAAERPGHFAGMVLIS----PLVLA 151 RDV+ + +++DY P +++ GHSMGG A P FA + ++ PL +A Sbjct: 91 RDVMDVIAEVRRDYKIDPDRIYMTGHSMGGYGTWSIAMNHPDVFAALAPVAGGGNPLGMA 150 Query: 152 N 152 N Sbjct: 151 N 151 >2E3J-A nrPDB Length = 356 Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust. Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 5/104 (4%) Query: 44 LIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVS-DFHVFVRDVLQ 102 L+ + HG E + L G V A D G+G+S R+ + V DV+ Sbjct: 29 LVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGDVVG 88 Query: 103 HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS 146 +DS Y F++GH G +A A P AG+V IS Sbjct: 89 VLDS----YGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGIS 128 >1DT3-A nrPDB Length = 269 Score = 31.6 bits (70), Expect = 0.48, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Query: 97 VRDVL-QHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGH 138 V D L Q V+ +++P V GHS+GGA+A + A+ G+ Sbjct: 120 VADTLRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLRGN 162 >6CHS-A nrPDB Length = 659 Score = 30.8 bits (68), Expect = 0.69, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 9/45 (20%) Query: 37 PTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHG 81 PT PK++ +H +G S R +E+AR +G VGHG Sbjct: 35 PTVDPKSITLSNHPSGGDSKRIDEIARFKIG---------QVGHG 70 >4S3P-A nrPDB Length = 696 Score = 30.8 bits (68), Expect = 0.76, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 25/42 (59%) Query: 129 ILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLV 170 ++ A+R G F G+ I L ANPESA+ + + + LN++ Sbjct: 171 LVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVI 212 >6BJE-A nrPDB Length = 222 Score = 30.4 bits (67), Expect = 0.91, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 5/64 (7%) Query: 97 VRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS---PLVLANP 153 ++ +++H M+ P + L G S GGA+++ TA P AG+V +S PL A P Sbjct: 90 IKALIEH--EMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFP 147 Query: 154 ESAT 157 ++A Sbjct: 148 QAAN 151 >3FCX-A nrPDB Length = 282 Score = 30.4 bits (67), Expect = 0.92, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Query: 118 LLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 + GHSMGG A++ A + PG + + +P+ NP Sbjct: 145 IFGHSMGGHGALICALKNPGKYKSVSAFAPIC--NP 178 >5MRJ-A nrPDB Length = 396 Score = 30.4 bits (67), Expect = 0.93, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 25/53 (47%) Query: 249 LLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTAS 301 + A++ D K+Y Y++ + +VT + ++N WVSQ G S Sbjct: 245 IAFRAARAADPNAKLYINDYNLDNANYAKVTRGMVEKVNRWVSQGVPIDGIGS 297 >4TGL-A nrPDB Length = 269 Score = 30.4 bits (67), Expect = 0.93, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 16/24 (66%) Query: 109 KDYPGLPVFLLGHSMGGAIAILTA 132 K YP V + GHS+GGA A+L A Sbjct: 131 KQYPSYKVAVTGHSLGGATALLCA 154 >4IH4-A nrPDB Length = 267 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Query: 36 KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHV 95 + GT ++F++HG G + L + V +D V G + + + Sbjct: 13 RVVGTGDRILFLAHGFGTDQSAWH-LILPYFTQNYRVVLYDLVCAGSVNPDYFDFNRYTT 71 Query: 96 ---FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLI--SPLVL 150 +V D+L VDS+ +GHS+ I I+ + RP F+ ++LI SP L Sbjct: 72 LDPYVDDLLNIVDSLGIQNCAY----VGHSVSAMIGIIASIRRPELFSKLILIGFSPRFL 127 Query: 151 ANPESATTFK 160 + + F+ Sbjct: 128 NDEDYHGGFE 137 >6QPR-A nrPDB Length = 361 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 17/26 (65%) Query: 109 KDYPGLPVFLLGHSMGGAIAILTAAE 134 K YP V + GHS+GGA A+L A + Sbjct: 223 KQYPSYKVAVTGHSLGGATALLCALD 248 >4C2T-A nrPDB Length = 745 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 21/35 (60%) Query: 101 LQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAER 135 +Q++ QKDYP V++L H+ + +L AA + Sbjct: 268 IQNILDFQKDYPDAKVYMLEHNYRSSARVLEAANK 302 >4C2U-A nrPDB Length = 665 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 21/35 (60%) Query: 101 LQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAER 135 +Q++ QKDYP V++L H+ + +L AA + Sbjct: 268 IQNILDFQKDYPDAKVYMLEHNYRSSARVLEAANK 302 >6AP7-A nrPDB Length = 269 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 10/130 (7%) Query: 36 KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHV 95 + G+ + ++ ++HG G + + + D V +D V G + + Sbjct: 14 RVVGSGERVLVLAHGFGTDQSAWNRILPFFL-RDYRVVLYDLVCAGSVNPDFFDFRRYTT 72 Query: 96 ---FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLI--SPLVL 150 +V D+L +D++ D +GHS+ I IL + RP F+ ++LI SP L Sbjct: 73 LDPYVDDLLHILDALGIDQCAY----VGHSVSAMIGILASIRRPELFSKLILIGASPRFL 128 Query: 151 ANPESATTFK 160 + + F+ Sbjct: 129 NDEDYHGGFE 138 >4YCZ-A nrPDB Length = 876 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 16/86 (18%) Query: 1 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHG---------- 50 PE++SP + PYQ P + +G + W P G L+ HG Sbjct: 324 QPEQASPAKGFVKWPYQQRPKIDQQEGPSIPRTNWGPNGL---LVTTHHGEPSLQPADGT 380 Query: 51 --AGEHS-GRYEELARMLMGLDLLVF 73 A E S G E LAR+ +D + F Sbjct: 381 LAASEESVGSPENLARLQRYIDSVSF 406 >3V1K-A nrPDB Length = 286 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 118 LLGHSMGGAIAILTAAERPGHFAGMVLISP 147 L+G+SMGGA A+ A E P ++L+ P Sbjct: 108 LVGNSMGGATALNFALEYPDRIGKLILMGP 137 >4Q2T-A nrPDB Length = 607 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 5/80 (6%) Query: 160 KVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSR 219 KVL A+ LN +++ G I + LSRN+ I++ D ++ G + LL A +R Sbjct: 431 KVLTAEELNAAQTSVAYGCIKYADLSRNRLNDYIFSFDKMLDDRGNTAAY---LLYAFTR 487 Query: 220 VERALPKL-TVPFLLLQGSA 238 + R++ +L + +LQ +A Sbjct: 488 I-RSIARLANIDEEMLQKAA 506 >1LGY-A nrPDB Length = 269 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 9/79 (11%) Query: 90 VSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLV 149 +S + V D V +P V + GHS+GGA A+L AGM L Sbjct: 113 LSSYEQVVNDYFPVVQEQLTAHPTYKVIVTGHSLGGAQALL---------AGMDLYQREP 163 Query: 150 LANPESATTFKVLAAKVLN 168 +P++ + F V +V N Sbjct: 164 RLSPKNLSIFTVGGPRVGN 182 >3O0D-A nrPDB Length = 301 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 19/27 (70%) Query: 104 VDSMQKDYPGLPVFLLGHSMGGAIAIL 130 +DS+ + YP + + GHS+GGA A+L Sbjct: 144 LDSVIEQYPDYQIAVTGHSLGGAAALL 170 >3I4J-A nrPDB Length = 430 Score = 28.9 bits (63), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 8/64 (12%) Query: 77 HVGHGQSE-GERMVVSDFHV-------FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIA 128 ++GHG++E GERM + F DVL+ + GLP F GG+ A Sbjct: 42 NIGHGRAEVGERMAAQAARLPFVHGSQFSSDVLEEYAGRLARFVGLPTFRFWAVSGGSEA 101 Query: 129 ILTA 132 +A Sbjct: 102 TESA 105 >5GW8-A nrPDB Length = 286 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 22/39 (56%) Query: 96 FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAE 134 V D+ HV +++ V ++GHS+G AI +L + + Sbjct: 127 LVDDIFDHVKKFKQEKNESRVTVIGHSLGAAIGLLASLD 165 >3M5U-A nrPDB Length = 361 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 12/63 (19%) Query: 215 NAVSRVERALPKLTVPFLLLQGSADRLCDSKG-AYLLMELAK-----------SQDKTLK 262 NA+ ++ + T+P +L+ + LCD +G Y +ME++ +Q+K K Sbjct: 2 NAMRKINFSAGPSTLPLEILEQAQKELCDYQGRGYSIMEISHRTKVFEEVHFGAQEKAKK 61 Query: 263 IYE 265 +YE Sbjct: 62 LYE 64 >4XJV-A nrPDB Length = 271 Score = 28.1 bits (61), Expect = 4.5, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 9/102 (8%) Query: 32 CRYWKPTGTPKALIFVSHGAGE-HSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVV 90 C Y P T K + F G G H ++ + DLL + +S E + Sbjct: 24 CLYKNPEATFKLICFPWMGGGSTHFAKWGQDTH-----DLLEVHSLRLPGRESRVEEPLE 78 Query: 91 SDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTA 132 +D V +V+ + + +D P GHSMG IA TA Sbjct: 79 NDISQLVDEVVCALQPVIQDKP---FAFFGHSMGSYIAFRTA 117 >5CH8-A nrPDB Length = 279 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 12/47 (25%), Positives = 25/47 (53%) Query: 91 SDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPG 137 S + + D+++ + + P + ++GHS+G A+A L A + G Sbjct: 114 SSWKLVRDDIIKELKEVVAQNPNYELVVVGHSLGAAVATLAATDLRG 160 >2WUG-A nrPDB Length = 291 Score = 27.7 bits (60), Expect = 6.0, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Query: 23 VNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELAR--MLMGLDLLVFAHDHVGH 80 V+ DG + G + ++ + HG G + + +R ++ V A D G+ Sbjct: 18 VDVDGPLKLHYHEAGVGNDQTVVLL-HGGGPGAASWTNFSRNIAVLARHFHVLAVDQPGY 76 Query: 81 GQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLP-VFLLGHSMGGAIAILTAAERPGHF 139 G S+ +R F+ + L+ + D GL V L+G+++GG A+ A + P Sbjct: 77 GHSD-KRAEHGQFNRYAAMALKGL----FDQLGLGRVPLVGNALGGGTAVRFALDYPARA 131 Query: 140 AGMVLISP 147 +VL+ P Sbjct: 132 GRLVLMGP 139 >3LS2-A nrPDB Length = 280 Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 120 GHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 GHSMGG A++ A + P + SP+V NP Sbjct: 145 GHSMGGHGALMIALKNPQDYVSASAFSPIV--NP 176 >5XY3-c nrPDB Length = 112 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 1/49 (2%) Query: 38 TGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGE 86 G K +IF S+ A H E A ML G D+L F D+V G + G+ Sbjct: 39 NGEAKLVIFASNVAPAHRSLIEYYA-MLSGCDILPFDGDNVDLGTACGK 86 >3E4D-A nrPDB Length = 278 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 118 LLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESA 156 + GHSMGG A+ A + P F +P+V P SA Sbjct: 144 IFGHSMGGHGAMTIALKNPERFKSCSAFAPIVA--PSSA 180 >3NGM-A nrPDB Length = 319 Score = 27.3 bits (59), Expect = 8.2, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 112 PGLPVFLLGHSMGGAIAILTAAE 134 P V +GHS+GGA+A L A Sbjct: 134 PSFKVVSVGHSLGGAVATLAGAN 156 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3JWE-A nrPDB 413 e-116 4ZWN-A nrPDB 318 2e-87 6EIC-C nrPDB 295 1e-80 1A88-A nrPDB 230 6e-61 1A8S-A nrPDB 223 9e-59 4FBL-A nrPDB 205 2e-53 3C5W-P nrPDB 123 9e-29 Sequences not found previously or not previously below threshold: 4DGQ-A nrPDB 167 4e-42 3HEA-A nrPDB 167 6e-42 1A8Q-A nrPDB 145 2e-35 4IQ4-A nrPDB 128 3e-30 1BRO-A nrPDB 127 7e-30 3FOB-A nrPDB 121 4e-28 3RLI-A nrPDB 119 2e-27 1HKH-A nrPDB 117 5e-27 5XKS-A nrPDB 117 6e-27 4RNC-A nrPDB 101 4e-22 4UHD-A nrPDB 83 1e-16 5EGN-A nrPDB 83 2e-16 2E3J-A nrPDB 77 8e-15 1R1D-A nrPDB 76 2e-14 1U2E-A nrPDB 75 4e-14 4Y2Y-A nrPDB 71 5e-13 3HSS-A nrPDB 70 1e-12 1XRN-A nrPDB 69 3e-12 5Y6Y-B nrPDB 68 4e-12 4HTA-A nrPDB 68 5e-12 2XMZ-A nrPDB 68 7e-12 3KXP-A nrPDB 66 2e-11 3WMR-A nrPDB 66 2e-11 3OM8-A nrPDB 65 4e-11 2WUG-A nrPDB 65 4e-11 6AP7-A nrPDB 64 5e-11 3DYV-A nrPDB 63 1e-10 1CR6-A nrPDB 63 1e-10 2OCI-A nrPDB 62 3e-10 3V1K-A nrPDB 62 4e-10 4NMW-A nrPDB 60 1e-09 1QTR-A nrPDB 59 2e-09 1AZW-A nrPDB 57 1e-08 5UXZ-A nrPDB 57 1e-08 5HK8-A nrPDB 56 1e-08 6FKX-A nrPDB 56 3e-08 5YHP-A nrPDB 55 5e-08 5AOA-A nrPDB 54 6e-08 2WFL-A nrPDB 54 8e-08 3V48-A nrPDB 54 9e-08 4CCY-A nrPDB 53 1e-07 4IH4-A nrPDB 53 2e-07 1Y7H-A nrPDB 53 2e-07 3FCY-A nrPDB 53 2e-07 1M33-A nrPDB 53 2e-07 3O4I-A nrPDB 52 3e-07 3P2M-A nrPDB 51 4e-07 4NZZ-A nrPDB 51 6e-07 3KSR-A nrPDB 50 1e-06 3BF8-A nrPDB 50 1e-06 4NVR-A nrPDB 50 1e-06 1SCK-A nrPDB 49 2e-06 1R3D-A nrPDB 49 2e-06 2Y6V-A nrPDB 49 2e-06 2RON-A nrPDB 49 2e-06 4CCW-A nrPDB 49 3e-06 1Q0R-A nrPDB 48 4e-06 4GDM-A nrPDB 47 8e-06 2PSJ-A nrPDB 47 1e-05 4G5X-A nrPDB 46 2e-05 3WYD-A nrPDB 46 2e-05 2O2H-A nrPDB 46 2e-05 2YYS-A nrPDB 45 3e-05 3NWO-A nrPDB 44 8e-05 1DWO-A nrPDB 43 1e-04 6COB-A nrPDB 43 1e-04 5YP1-A nrPDB 41 4e-04 3A2L-A nrPDB 41 5e-04 6FVJ-A nrPDB 40 0.001 1UFO-A nrPDB 39 0.002 4QLA-A nrPDB 39 0.003 5XB6-A nrPDB 39 0.004 2EDA-A nrPDB 39 0.004 6AVW-A nrPDB 38 0.004 1HLG-A nrPDB 38 0.004 3CN7-A nrPDB 38 0.006 1TAH-B nrPDB 38 0.007 4EB0-A nrPDB 37 0.010 4YCZ-A nrPDB 37 0.010 2XLB-A nrPDB 37 0.011 3I6Y-A nrPDB 37 0.014 5YAL-A nrPDB 36 0.016 2JBW-A nrPDB 36 0.022 6IGR-A nrPDB 36 0.023 3AZQ-A nrPDB 35 0.038 2O7R-A nrPDB 35 0.043 5UGZ-A nrPDB 35 0.048 6ECE-A nrPDB 34 0.057 1AUO-A nrPDB 34 0.061 6CL4-A nrPDB 34 0.062 1DT3-A nrPDB 34 0.070 1OIL-A nrPDB 34 0.078 3AB1-A nrPDB 34 0.082 6BJE-A nrPDB 34 0.087 3HXK-A nrPDB 34 0.090 6GUD-A nrPDB 34 0.098 4Q3K-A nrPDB 34 0.11 2PPL-A nrPDB 34 0.12 5T88-A nrPDB 33 0.16 3H2H-A nrPDB 33 0.17 5LZ5-A nrPDB 33 0.21 5OLJ-A nrPDB 33 0.23 1EX9-A nrPDB 33 0.26 5DWD-A nrPDB 32 0.28 6GI5-A nrPDB 32 0.30 1FJ2-A nrPDB 32 0.34 4XJV-A nrPDB 31 0.47 1HPL-A nrPDB 31 0.51 1JFR-A nrPDB 31 0.55 1BU8-A nrPDB 31 0.55 2HDW-A nrPDB 31 0.85 1ODT-C nrPDB 31 0.98 3E4D-A nrPDB 30 1.0 4TGL-A nrPDB 30 1.1 4WFK-A nrPDB 30 1.2 6QPR-A nrPDB 30 1.4 1LGY-A nrPDB 30 1.5 3LWA-A nrPDB 30 1.6 5UNO-A nrPDB 30 1.7 1KEH-A nrPDB 29 1.9 5KRE-A nrPDB 29 1.9 3O0D-A nrPDB 29 2.3 3FCX-A nrPDB 29 2.5 3FLA-A nrPDB 29 3.4 5DU2-A nrPDB 28 4.3 5W8P-A nrPDB 28 7.5 >3JWE-A nrPDB Length = 320 Score = 413 bits (1061), Expect = e-116, Method: Composition-based stats. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE 60 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE Sbjct: 18 MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE 77 Query: 61 LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG 120 LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG Sbjct: 78 LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG 137 Query: 121 HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID 180 HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID Sbjct: 138 HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID 197 Query: 181 SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR 240 SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR Sbjct: 198 SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR 257 Query: 241 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA 300 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA Sbjct: 258 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA 317 Query: 301 SPP 303 SPP Sbjct: 318 SPP 320 >4ZWN-A nrPDB Length = 334 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 73/312 (23%), Positives = 130/312 (41%), Gaps = 29/312 (9%) Query: 7 PRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLM 66 P + ++P + A Y+F T + + + HG GE++ L L Sbjct: 26 PYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLS 85 Query: 67 GLDLLVFAHDHVGHGQSEGERM--VVSDFHVFVRDVLQHVDS--MQKDYPGLPVFLLGHS 122 F D G G + R V ++HVF D+ V+ + G+P+F+ GHS Sbjct: 86 LNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF-NDLEHFVEKNLSECKAKGIPLFMWGHS 144 Query: 123 MGGAIAILTAAE--RPGHFAGMVLISPLVLANPESATTFKV-LAAKVLNLVLPNLSLG-P 178 MGG I + A + +G + PL++ +P + + A +L P + + Sbjct: 145 MGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFSPRVRIDTG 204 Query: 179 IDSSVLSRNKTEVDIYNSDPL-------------ICRAGLKVCFGIQLLNAVSRVERALP 225 +D ++ +K SDP+ + G K+ N + +++ Sbjct: 205 LDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKL-----YKNENNYIQKNFA 259 Query: 226 KLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH-VLHKELPEVTNSVFH 284 K P +++ G D + D KG+ + S DK LK+Y GA H + E +V N+VF+ Sbjct: 260 K-DKPVIIMHGQDDTINDPKGSEKFIRDCPSADKELKLYPGARHSIFSLETDKVFNTVFN 318 Query: 285 EINMWVSQRTAT 296 ++ W+ + T T Sbjct: 319 DMKQWLDKHTTT 330 >6EIC-C nrPDB Length = 279 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 95/273 (34%), Positives = 145/273 (53%), Gaps = 3/273 (1%) Query: 21 HLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGH 80 + + W P P+A++ ++HG GEH+ RY+ +A+ L L+ +A DH GH Sbjct: 9 NFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGH 68 Query: 81 GQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFA 140 G+S G+R++V D + D V ++YPG +LGHSMGG I ERP ++ Sbjct: 69 GRSGGKRVLVRDISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYGVERPDNYD 128 Query: 141 GMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLI 200 MVL +P V A + + +AAK+L +V+P L + +D + +SR+ V YN+DPL+ Sbjct: 129 LMVLSAPAVAAQ-DLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNTDPLV 187 Query: 201 CRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKT 260 + G LL + R P LT P L+L G+ DRL +G+ L+E S D Sbjct: 188 HHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRLIPIEGSRRLVECVGSADVQ 247 Query: 261 LKIYEGAYHVLHKELPEVTNSVFHEINMWVSQR 293 LK Y G YH + E PE N V ++ W+++R Sbjct: 248 LKEYPGLYHEVFNE-PE-RNQVLDDVVAWLTER 278 >1A88-A nrPDB Length = 275 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 69/286 (24%), Positives = 110/286 (38%), Gaps = 49/286 (17%) Query: 22 LVNADGQYLFCRYWKP-TGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGH 80 + +DG +F + W P G P + HG + ++ + V AHD GH Sbjct: 3 VTTSDGTNIFYKDWGPRDGLP---VVFHHGWPLSADDWDNQMLFFLSHGYRVIAHDRRGH 59 Query: 81 GQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGHF 139 G+S+ + D + DV +++ D G +GHS GG +A A PG Sbjct: 60 GRSD-QPSTGHDMDTYAADVAALTEAL--DLRG--AVHIGHSTGGGEVARYVARAEPGRV 114 Query: 140 AGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDI------ 193 A VL+S + +S T L +V + L +R + +D+ Sbjct: 115 AKAVLVSAVPPVMVKSDTNPDGLPLEVFDEFRAAL--------AANRAQFYIDVPSGPFY 166 Query: 194 -YNSDPLICRAGLKVCFGIQ-----------LLNAVSRVE--RALPKLTVPFLLLQGSAD 239 +N + GL + +Q + A S + L ++ VP L+ G+ D Sbjct: 167 GFNREGATVSQGLIDHWWLQGMMGAANAHYECIAAFSETDFTDDLKRIDVPVLVAHGTDD 226 Query: 240 RLCD-----SKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTN 280 ++ K A LL + TLK YEG H + PEV N Sbjct: 227 QVVPYADAAPKSAELL------ANATLKSYEGLPHGMLSTHPEVLN 266 >1A8S-A nrPDB Length = 273 Score = 223 bits (567), Expect = 9e-59, Method: Composition-based stats. Identities = 64/281 (22%), Positives = 108/281 (38%), Gaps = 39/281 (13%) Query: 22 LVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHG 81 DG ++ + W G+ + ++F SHG ++ +E L V AHD GHG Sbjct: 3 FTTRDGTQIYYKDW---GSGQPIVF-SHGWPLNADSWESQMIFLAAQGYRVIAHDRRGHG 58 Query: 82 QSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGHFA 140 +S + +D + D+ Q ++ + L G S GG +A A Sbjct: 59 RSS-QPWSGNDMDTYADDLAQLIEHLDLR----DAVLFGFSTGGGEVARYIGRHGTARVA 113 Query: 141 GMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDI------- 193 LIS + ++ L +V + G +S+ R++ D+ Sbjct: 114 KAGLISAVPPLMLKTEANPGGLPMEVFD--------GIRQASLADRSQLYKDLASGPFFG 165 Query: 194 YNSDPLICRAGLKVCFGIQ-----------LLNAVSRVE--RALPKLTVPFLLLQGSADR 240 +N AG+ F +Q + A S + L K+ VP L++ G AD+ Sbjct: 166 FNQPGAKSSAGMVDWFWLQGMAAGHKNAYDCIKAFSETDFTEDLKKIDVPTLVVHGDADQ 225 Query: 241 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNS 281 + + A + A + TLKIY GA H L + N+ Sbjct: 226 VVPIE-ASGIASAALVKGSTLKIYSGAPHGLTDTHKDQLNA 265 >4FBL-A nrPDB Length = 281 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 57/234 (24%), Positives = 94/234 (40%), Gaps = 21/234 (8%) Query: 45 IFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHV 104 + VSHG LA V GHG + E M S + D++ + Sbjct: 54 VLVSHGFTGSPQSMRFLAEGFARAGYTVATPRLTGHGTTPAE-MAASTASDWTADIVAAM 112 Query: 105 DSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLI-SPLVLANPESATTFKVLA 163 +++ L F+ G SMGGA+ + A + P FAG++ I + L + +P+ LA Sbjct: 113 RWLEERCDVL--FMTGLSMGGALTVWAAGQFPERFAGIMPINAALRMESPD-------LA 163 Query: 164 AKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERA 223 A N P L I S + + E+ + P+ +K L+ + E Sbjct: 164 ALAFNPDAP-AELPGIGSDIKAEGVKEL----AYPVTPVPAIK-----HLITIGAVAEML 213 Query: 224 LPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPE 277 LP++ P L++Q D + L+ S +K L E +YHV + + Sbjct: 214 LPRVKCPALIIQSREDHVVPPHNGELIYNGIGSTEKELLWLENSYHVATLDNDK 267 >4DGQ-A nrPDB Length = 280 Score = 167 bits (423), Expect = 4e-42, Method: Composition-based stats. Identities = 52/288 (18%), Positives = 99/288 (34%), Gaps = 37/288 (12%) Query: 22 LVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHG 81 + DG +F + W P +I HG S ++ + V AHD GHG Sbjct: 8 VTTKDGVEIFYKDWGPRDA--KVIHFHHGWPLSSDDWDAQLLFFVNKGFRVVAHDRRGHG 65 Query: 82 QSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGHFA 140 +S + D + D V+ + +GHS GG + A + + Sbjct: 66 RSS-QVWDGHDMDHYADDAAAVVEKLGTH----GAMHVGHSTGGGEVVRYIARHGERNVS 120 Query: 141 GMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDI------- 193 VLIS + ++++ V + ++ +R + +D+ Sbjct: 121 KAVLISSVPPLMVKTSSNPNGTPKSVFDDFQAHV--------AANRAQFYLDVPAGPFYG 172 Query: 194 YNSDPLICRAGLKVCFGIQ-----------LLNAVSRVE--RALPKLTVPFLLLQGSADR 240 YN G+ + Q + A S+ + L +T+P L++ G D+ Sbjct: 173 YNRPGAKPSEGVIYNWWRQGMMGSTKAQYDGIVAFSQTDFTNDLKGITIPVLVIHGDDDQ 232 Query: 241 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINM 288 + ++ ++ L Y+GA H + + N+ E Sbjct: 233 VV-PYADSGVLSAKLVKNGKLITYKGAPHGIPTTHADKVNADLLEFLQ 279 >3HEA-A nrPDB Length = 271 Score = 167 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 95/271 (35%), Gaps = 21/271 (7%) Query: 22 LVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHG 81 V DG ++ + W G+ K + SHG + +E L A D G G Sbjct: 3 FVAKDGTQIYFKDW---GSGKP-VLFSHGWPLDADMWEYQMEYLSSRGYRTIAFDRRGFG 58 Query: 82 QSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGHFA 140 +S+ + +D+ F D+ Q ++ + V L+G SMGG +A A A Sbjct: 59 RSD-QPWTGNDYDTFADDIAQLIEHLDLK----EVTLVGFSMGGGDVARYIARHGSARVA 113 Query: 141 GMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID--------SSVLSRNKTEVD 192 G+VL+ + + + + V L +++ + Sbjct: 114 GLVLLGAVTPIFGQKPDYPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINKGQVVSQ 173 Query: 193 IYNSDPLICRAGLKVCFGIQLLNAVSRVE--RALPKLTVPFLLLQGSADRLCDSKGAYLL 250 + L + + + A + + + K+ VP L++ G D++ + + Sbjct: 174 GVQTQTLQIALLASLKATVDCVTAFAETDFRPDMAKIDVPTLVIHGDGDQIVPFETTGKV 233 Query: 251 MELAKSQDKTLKIYEGAYHVLHKELPEVTNS 281 + LK+Y+ A H + N Sbjct: 234 A-AELIKGAELKVYKDAPHGFAVTHAQQLNE 263 >1A8Q-A nrPDB Length = 274 Score = 145 bits (365), Expect = 2e-35, Method: Composition-based stats. Identities = 51/267 (19%), Positives = 94/267 (35%), Gaps = 28/267 (10%) Query: 20 PHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVG 79 P DG +F + W G + ++F+ HG + +++ + ++ AHD G Sbjct: 1 PICTTRDGVEIFYKDW---GQGRPVVFI-HGWPLNGDAWQDQLKAVVDAGYRGIAHDRRG 56 Query: 80 HGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGH 138 HG S DF F ++ + D V L+ HSMGG +A G Sbjct: 57 HGHSTP-VWDGYDFDTFAD----DLNDLLTDLDLRDVTLVAHSMGGGELARYVGRHGTGR 111 Query: 139 FAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDP 198 VL+S + +S + +V + + + + N Sbjct: 112 LRSAVLLSAIPPVMIKSDKNPDGVPDEVFDALKNGVLTERSQFWKDTAEGFFSA--NRPG 169 Query: 199 LICRAGLKVCFG-----------IQLLNAVSRVE--RALPKLTVPFLLLQGSADRLCDSK 245 G K F ++ ++A + L K +P L++ G D++ Sbjct: 170 NKVTQGNKDAFWYMAMAQTIEGGVRCVDAFGYTDFTEDLKKFDIPTLVVHGDDDQVVPID 229 Query: 246 G-AYLLMELAKSQDKTLKIYEGAYHVL 271 ++ + LK+YEG+ H + Sbjct: 230 ATGRKSAQIIP--NAELKVYEGSSHGI 254 >4IQ4-A nrPDB Length = 456 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 45/264 (17%), Positives = 87/264 (32%), Gaps = 22/264 (8%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 Y++ GT ++ + HG +E + L+ V +D G GQS + D+ Sbjct: 17 YYEDHGTGTPVVLI-HGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSS-QPTTGYDY 74 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG-GAIAILTAAERPGHFAGMVLISPLVLAN 152 F D+ ++++ L+G SMG G +A ++ A + ++ L Sbjct: 75 DTFAADLNTVLETLDLQ----DAVLVGFSMGTGEVARYVSSYGTARIAAVAFLASLEPFL 130 Query: 153 PESATTFKV-LAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGI 211 ++ + + ++ + N N I ++ + Sbjct: 131 LKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSWNT 190 Query: 212 QLLNAVSRVER-----------ALPKLTVPFLLLQGSADRLCDSKG-AYLLMELAKSQDK 259 +P++ VP L+L G+ DR + A + + S Sbjct: 191 AASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSA-- 248 Query: 260 TLKIYEGAYHVLHKELPEVTNSVF 283 EGA H L E N+ Sbjct: 249 EYVEVEGAPHGLLWTHAEEVNTAL 272 >1BRO-A nrPDB Length = 277 Score = 127 bits (318), Expect = 7e-30, Method: Composition-based stats. Identities = 45/264 (17%), Positives = 88/264 (33%), Gaps = 22/264 (8%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 Y++ GT + ++ + HG +E + L+ V +D G GQS + D+ Sbjct: 16 YYEDHGTGQPVVLI-HGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSS-QPTTGYDY 73 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG-GAIAILTAAERPGHFAGMVLISPLVLAN 152 F D+ ++++ L+G SMG G +A ++ A + ++ L Sbjct: 74 DTFAADLNTVLETLDLQ----DAVLVGFSMGTGEVARYVSSYGTARIAKVAFLASLEPFL 129 Query: 153 PESATTFKV-LAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGI 211 ++ + + ++ + N N I ++ + Sbjct: 130 LKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSWNT 189 Query: 212 QLLNAVSRVER-----------ALPKLTVPFLLLQGSADRLCDSKG-AYLLMELAKSQDK 259 +P++ VP L+L G+ DR + A + + S Sbjct: 190 AASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSA-- 247 Query: 260 TLKIYEGAYHVLHKELPEVTNSVF 283 EGA H L E N+ Sbjct: 248 EYVEVEGAPHGLLWTHAEEVNTAL 271 >3C5W-P nrPDB Length = 310 Score = 123 bits (308), Expect = 9e-29, Method: Composition-based stats. Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 4/129 (3%) Query: 6 SPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEEL-ARM 64 SP Q + + N G+ F Y +G+ ++ + HG G + + A + Sbjct: 8 SPVPWSQYFESMEDVEVENETGKDTFRVY--KSGSEGPVLLLLHGGGHSALSWAVFTAAI 65 Query: 65 LMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG 124 + + + A D HG+++ + +DV V++M D P P+ L+GH+MG Sbjct: 66 ISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPP-PIMLIGHAMG 124 Query: 125 GAIAILTAA 133 GAIA+ TA+ Sbjct: 125 GAIAVHTAS 133 >3FOB-A nrPDB Length = 281 Score = 121 bits (303), Expect = 4e-28, Method: Composition-based stats. Identities = 48/265 (18%), Positives = 95/265 (35%), Gaps = 24/265 (9%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 Y++ GT K ++ + HG +E L+ V +D G G+S + ++ Sbjct: 20 YYEDHGTGKPVVLI-HGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSS-QPWEGYEY 77 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGA-IAILTAAERPGHFAGMVLISPLVL-- 150 F D+ Q ++ ++ V L+G SMGG +A + +V + Sbjct: 78 DTFTSDLHQLLEQLE----LQNVTLVGFSMGGGEVARYISTYGTDRIEKVVFAGAVPPYL 133 Query: 151 ----ANPESATTFKVLAAKVLNLVLPNLSLGPID------SSVLSRNKTEVDIYNSDPLI 200 +PE A + + + N L +D + R + + Sbjct: 134 YKSEDHPEGALDDATI--ETFKSGVINDRLAFLDEFTKGFFAAGDRTDLVSESFRLYNWD 191 Query: 201 CRAGLKVCFGIQLLNAVSRVE--RALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQD 258 AG + + A S+ + + L K +P L++ G +D + + L A + Sbjct: 192 IAAGASPKGTLDCITAFSKTDFRKDLEKFNIPTLIIHGDSDATVPFEYSGKLTHEA-IPN 250 Query: 259 KTLKIYEGAYHVLHKELPEVTNSVF 283 + + +G H L+ + N Sbjct: 251 SKVALIKGGPHGLNATHAKEFNEAL 275 >3RLI-A nrPDB Length = 270 Score = 119 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 50/261 (19%), Positives = 91/261 (34%), Gaps = 29/261 (11%) Query: 17 QDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHD 76 + P L A+ F P G + + HG LA V Sbjct: 23 EQYPVLSGAE---PFYAENGPVG-----VLLVHGFTGTPHSMRPLAEAYAKAGYTVCLPR 74 Query: 77 HVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP 136 GHG + E M + FH +V V + +++ +F+ G SMGG + + A P Sbjct: 75 LKGHG-THYEDMERTTFHDWVASVEEGYGWLKQRCQ--TIFVTGLSMGGTLTLYLAEHHP 131 Query: 137 GHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNS 196 G+V I+ V +AA + L I S + + + E+ + Sbjct: 132 D-ICGIVPINAAV--------DIPAIAAGMTGGGELPRYLDSIGSDLKNPDVKELAYEKT 182 Query: 197 DPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKS 256 +QL +++ + L ++ P L+ D + A ++ + S Sbjct: 183 PTASL---------LQLARLMAQTKAKLDRIVCPALIFVSDEDHVVPPGNADIIFQGISS 233 Query: 257 QDKTLKIYEGAYHVLHKELPE 277 +K + +YHV + + Sbjct: 234 TEKEIVRLRNSYHVATLDYDQ 254 >1HKH-A nrPDB Length = 279 Score = 117 bits (293), Expect = 5e-27, Method: Composition-based stats. Identities = 46/270 (17%), Positives = 84/270 (31%), Gaps = 32/270 (11%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 Y++ G+ + ++ + HG +E R L+ V +D G G S + D+ Sbjct: 16 YYEDQGSGQPVVLI-HGYPLDGHSWERQTRELLAQGYRVITYDRRGFGGSS-KVNTGYDY 73 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG-GAIAILTAAERPGHFAGMVLISPLVLAN 152 F D+ ++++ V L+G SMG G +A A A + ++ L Sbjct: 74 DTFAADLHTVLETLDLR----DVVLVGFSMGTGELARYVARYGHERVAKLAFLASLEPFL 129 Query: 153 PESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSD---PLICRAGLKVCF 209 + + + +V + + + YN D Sbjct: 130 VQRDDNPEGVPQEVFD----GIEAAAKGDRFAWFTDFYKNFYNLDENLGSRISEQAVTGS 185 Query: 210 GIQLL-----NAVSRVE----------RALPKLTVPFLLLQGSADRLCDSKG-AYLLMEL 253 + A + V A+ P L+L G+ D + A + Sbjct: 186 WNVAIGSAPVAAYAVVPAWIEDFRSDVEAVRAAGKPTLILHGTKDNILPIDATARRFHQA 245 Query: 254 AKSQDKTLKIYEGAYHVLHKELPEVTNSVF 283 D EGA H L + N+ Sbjct: 246 VPEAD--YVEVEGAPHGLLWTHADEVNAAL 273 >5XKS-A nrPDB Length = 256 Score = 117 bits (293), Expect = 6e-27, Method: Composition-based stats. Identities = 46/249 (18%), Positives = 79/249 (31%), Gaps = 23/249 (9%) Query: 45 IFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHV 104 I V HG L V GHG + E M + ++ V Sbjct: 23 ILVLHGFTGSPQSMRPLGEAYHEAGYTVCGPRLKGHG-THYEDMEKTTCQDWIDSVEAGY 81 Query: 105 DSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAA 164 + ++ +F+ G SMGG + + A P G+ I+ + LA Sbjct: 82 EWLKNRC--GTIFVTGLSMGGTLTLYMAEHHP-EICGIAPINAAI--------NMPALAG 130 Query: 165 KVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERAL 224 + + L I S + E+ + R Q++ + RV+ L Sbjct: 131 ALAGVGDLPRFLDAIGSDIKKPGVKELAYEKTPAASIR---------QIVQLMERVKTDL 181 Query: 225 PKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFH 284 K+T P +L D + A + + S DK L +YHV + + Sbjct: 182 HKITCPAILFCSDEDHVVPPDNAPFIYDHIASADKKLVRLPDSYHVATLDND--RQKIID 239 Query: 285 EINMWVSQR 293 + + Sbjct: 240 TSLAFFKKH 248 >4RNC-A nrPDB Length = 310 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 64/308 (20%), Positives = 99/308 (32%), Gaps = 37/308 (12%) Query: 10 TPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLD 69 P+ + V+ DG + R + + + HG + S + E + D Sbjct: 15 VPRGSHMMSIREAVSVDGTSIVYRVTG--NSAGTPLVLLHGWAQSSQCWGEQVLADLAAD 72 Query: 70 LLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGG-AIA 128 + A D GHG S+ D + DV + + + LLG S GG I Sbjct: 73 YRLIAVDLRGHGYSDAPESGYDDSANWAGDVAAVLAA---EGVTENAILLGWSYGGLVIC 129 Query: 129 ILTAAERPGHFAGMVLI----------------SPLVLANPESATTFKVLAAKVLNLVLP 172 AA G AG VL+ S + A P + + A + L Sbjct: 130 DYLAAHGTGAVAGAVLVGAITSIGRGEKGGKVGSAMRSAVPGAMSEDPREAIRALGAFGN 189 Query: 173 NLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFL 232 L+ P S+ L R ++ L N + L L +P L Sbjct: 190 ALTGPPEGKGAASQALF------GYSLSTRPRVRA----ALFNRAVGHDELLRNLDIPVL 239 Query: 233 LLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQ 292 +L G+ D + D EL + + G H E P E+ ++S Sbjct: 240 VLHGTDDSVVDVSAGKHAEELIPKSQAS--YWVGCNHGPFVEDPTRF---VSEVRTFISS 294 Query: 293 RTATAGTA 300 AG A Sbjct: 295 LGKLAGAA 302 >4UHD-A nrPDB Length = 282 Score = 83.4 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 88/273 (32%), Gaps = 25/273 (9%) Query: 35 WKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFH 94 ++ TGT + + HG ++ L + V D G G+S+ V Sbjct: 20 FEDTGTGLP-VLLVHGFPLDRTMWKAQREELC-DEFRVIVPDLRGFGESQVIPGVA-TME 76 Query: 95 VFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLI-SPLVLANP 153 D+ + + + L G SMGG +A A + AG++L + +P Sbjct: 77 AMADDLAGLCNHLGL---TGKIVLGGLSMGGYVAFAFARKYRDRLAGLILCDTRARPDSP 133 Query: 154 ESATTFKVL--------AAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGL 205 E+ + + + ++P L + + + S P A Sbjct: 134 EAKENRRRVAERVRREGPGFIAEEMIPRLCCESTFRNHPEVIEKIRQMILSAPPEGVAAA 193 Query: 206 KVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYE 265 + + LP L+ P L+L G D + + + + Sbjct: 194 ALG-----MAERPDSTDLLPALSCPTLVLVGQFDAISPPEEMEAMARTIP--QSQFVVIP 246 Query: 266 GAYHVLHKELPEVTNSVFHEINMWVSQRTATAG 298 A H+ E PE V I W+ + AG Sbjct: 247 DAGHLPPMEQPE---RVTQAIREWLRKVHTEAG 276 >5EGN-A nrPDB Length = 271 Score = 82.6 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 50/279 (17%), Positives = 98/279 (35%), Gaps = 27/279 (9%) Query: 19 LPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHV 78 +PH+ N DG + Y+ G ++F+ H + G + + V DH Sbjct: 1 MPHVEN-DGVKI---YYDSYGEGVPIVFL-HPFSTNGGIWYFQTFPFAQTNH-VIVIDHR 54 Query: 79 GHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGH 138 GHG+S+ + DV+ +D+++ D +G+S+GG IA+ + P Sbjct: 55 GHGRSD-KPATGYSIMEHADDVVAVLDALKVD----RAVFVGNSIGGMIAMQLNLDHPQR 109 Query: 139 FAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDP 198 G +++S + A G ++ +V +R+K E + Sbjct: 110 VIGNLILS----SGTGLGEGMPPEAGAAFQNDYIGAFGGLLEGAVSARSKRERPEILAV- 164 Query: 199 LICRAGLKVCFGIQLLNAVSR---------VERALPKLTVPFLLLQGSADRLCDSKGAYL 249 + + F + +A + ++ L + P L++ G D + L Sbjct: 165 MKAHFSVPSNFPKHVFDAATADPNGVFAWNIKDRLSSIQAPTLVVAGEEDLVTTVANNQL 224 Query: 250 LMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINM 288 L + L++ H E P N + Sbjct: 225 LADNIP--GAELRVINDVGHFYQLERPSEFNELLRGFVA 261 >2E3J-A nrPDB Length = 356 Score = 77.2 bits (188), Expect = 8e-15, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 55/157 (35%), Gaps = 10/157 (6%) Query: 18 DLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDH 77 + ++N G + P L+ + HG E + L G V A D Sbjct: 3 QVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQ 62 Query: 78 VGHGQSEGERMV-VSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP 136 G+G+S R+ V DV+ +DS Y F++GH G +A A P Sbjct: 63 RGYGRSSKYRVQKAYRIKELVGDVVGVLDS----YGAEQAFVVGHDWGAPVAWTFAWLHP 118 Query: 137 GHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPN 173 AG+V IS P + L P+ Sbjct: 119 DRCAGVVGISV-----PFAGRGVIGLPGSPFGERRPS 150 >1R1D-A nrPDB Length = 247 Score = 75.7 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 41/253 (16%), Positives = 93/253 (36%), Gaps = 24/253 (9%) Query: 40 TPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRD 99 + + + HG +S L R L A + GHG E +V + + +D Sbjct: 14 AGERAVLLLHGFTGNSADVRMLGRFLESKGYTCHAPIYKGHGV-PPEELVHTGPDDWWQD 72 Query: 100 VLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMV-LISPLVLANPESATT 158 V+ ++ + + G S+GG ++ P G+V + +P+ + + E+ Sbjct: 73 VMNGYQFLKNK-GYEKIAVAGLSLGGVFSLKLGYTVP--IEGIVTMCAPMYIKSEETMYE 129 Query: 159 FKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVS 218 ++ + + + E++ + P+ L+ + Sbjct: 130 ---------GVLEYAREYKKREGKSEEQIEQEMERFKQTPMKTLKALQELI--------A 172 Query: 219 RVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEV 278 V L + P ++Q D + + A ++ +S K +K YE + HV+ L + Sbjct: 173 DVRAHLDLVYAPTFVVQARHDEMINPDSANIIYNEIESPVKQIKWYEQSGHVI--TLDQE 230 Query: 279 TNSVFHEINMWVS 291 + + +I ++ Sbjct: 231 KDQLHEDIYAFLE 243 >1U2E-A nrPDB Length = 289 Score = 74.9 bits (182), Expect = 4e-14, Method: Composition-based stats. Identities = 42/290 (14%), Positives = 90/290 (31%), Gaps = 27/290 (9%) Query: 8 RRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARM--- 64 + ++ + ++ G + + HG+G + + +R Sbjct: 4 YQPQTEAATSRFLNV--EEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDP 61 Query: 65 LMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG 124 L+ V D G G+S+ S + R + VD + + LLG+SMG Sbjct: 62 LVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNARILKSVVDQL----DIAKIHLLGNSMG 117 Query: 125 GAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVL 184 G ++ + P +VL+ + F + + + + I++ L Sbjct: 118 GHSSVAFTLKWPERVGKLVLMG----GGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKL 173 Query: 185 SRNKTEVDIYNSDPLICRAGLKVCFGIQ-----LLNAVSRVERALP-------KLTVPFL 232 + D + + A L + + ++ + P ++ L Sbjct: 174 MMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTL 233 Query: 233 LLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSV 282 ++ G DR L+ L I+ H E + N + Sbjct: 234 IVWGRNDRFVPMDAGLRLLSGI--AGSELHIFRDCGHWAQWEHADAFNQL 281 >4Y2Y-A nrPDB Length = 561 Score = 71.4 bits (173), Expect = 5e-13, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 45/129 (34%), Gaps = 6/129 (4%) Query: 42 KALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGER-MVVSDFHVFVRDV 100 + + HG E + L V A D G+G+S + V +++ Sbjct: 258 GPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEM 317 Query: 101 LQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHF-AGMVLISPLVLANPESATTF 159 + +D + +GH GG + A P A L +P + ANP + Sbjct: 318 VTFLDKLGLS----QAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLE 373 Query: 160 KVLAAKVLN 168 + A V + Sbjct: 374 SIKANPVFD 382 >3HSS-A nrPDB Length = 293 Score = 69.9 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 39/261 (14%), Positives = 82/261 (31%), Gaps = 25/261 (9%) Query: 35 WKPTGTPKALIFVSHGAGEHSGRYE-ELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 + GT ++F++ G G + + D+ G G + E Sbjct: 37 YDDNGTGDPVVFIA-GRGGAGRTWHPHQVPAFLAAGYRCITFDNRGIGAT--ENAEGFTT 93 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 V D ++++ P ++G SMG IA P + VL++ Sbjct: 94 QTMVADTAALIETL----DIAPARVVGVSMGAFIAQELMVVAPELVSSAVLMA-TRGRLD 148 Query: 154 ESATTFKVLAAKVLNL--------VLPNLSLGPIDSSVLSRNKTE---VDIYNSDPLICR 202 + F A++ + L L+ + + +++ P+ Sbjct: 149 RARQFFNKAEAELYDSGVQLPPTYDARARLLENFSRKTLNDDVAVGDWIAMFSMWPIKST 208 Query: 203 AGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLK 262 GL+ + +R+ A + P L++ + D + + + + Sbjct: 209 PGLRCQ--LDCAPQTNRLP-AYRNIAAPVLVIGFADDVVTPPYLGREVADALP--NGRYL 263 Query: 263 IYEGAYHVLHKELPEVTNSVF 283 A H+ E PE N+ Sbjct: 264 QIPDAGHLGFFERPEAVNTAM 284 >1XRN-A nrPDB Length = 293 Score = 68.7 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 53/296 (17%), Positives = 97/296 (32%), Gaps = 43/296 (14%) Query: 19 LPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHV 78 + + +G Y++ + K KA + HG S Y R + + V +D Sbjct: 6 IENYAKVNGIYIYYKLCKAP-EEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQF 64 Query: 79 GHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGH 138 G G+SE V + + + VFL+G S GGA+A+ A + H Sbjct: 65 GCGRSEEPDQSKFTIDYGVEEAEALRSKLFGN---EKVFLMGSSYGGALALAYAVKYQDH 121 Query: 139 FAGMV---LISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYN 195 G++ +S + L E L AK + ++ SS N + N Sbjct: 122 LKGLIVSGGLSSVPLTVKEMNRLIDELPAKYRD------AIKKYGSSGSYENPEYQEAVN 175 Query: 196 SDPLICRAGLKVCFGIQLLNAVSRVERA--------------------------LPKLTV 229 + + ++L ++ ER + + + Sbjct: 176 YFYHQHLLRSED-WPPEVLKSLEYAERRNVYRIMNGPNQFTITGTIKDWDITDKISAIKI 234 Query: 230 PFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHE 285 P L+ G D + A ++ E L ++ H+ E E N + + Sbjct: 235 PTLITVGEYDEVT-PNVARVIHEKI--AGSELHVFRDCSHLTMWEDREGYNKLLSD 287 >5Y6Y-B nrPDB Length = 326 Score = 68.3 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 43/120 (35%), Gaps = 8/120 (6%) Query: 41 PKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVF--VR 98 ++ HG E + L A D G+G +E + +S + F V Sbjct: 23 EGPVVLFLHGFPELWYSWRHQILALSSRGYRAVAPDLRGYGDTEA-PVSISSYTGFHIVG 81 Query: 99 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMV-LISPLVLANPESAT 157 D++ +D + D VFL+ H G I P V L PL+ +P T Sbjct: 82 DLIALIDLLGVD----QVFLVAHDWGAIIGWYLCTFHPDRVKAYVCLSVPLLHRDPNIRT 137 >4HTA-A nrPDB Length = 288 Score = 68.0 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 44/265 (16%), Positives = 96/265 (36%), Gaps = 23/265 (8%) Query: 39 GTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHV--- 95 G+ +A I + HG G ++ L L+ D V +D++G G + + + Sbjct: 32 GSGEATIVLGHGFGTDQSVWKHLVPHLV-DDYRVVLYDNMGAGTTNPDYFDFDRYSNLEG 90 Query: 96 FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPES 155 + D++ ++ D +GHS+ I +L + RP F+ +V+IS + Sbjct: 91 YSFDLIAILE----DLKIESCIFVGHSVSAMIGVLASLNRPDLFSKIVMISASPRYVNDV 146 Query: 156 ATT---FKVLAAKVLNLVLPNLSLGPIDSS----VLSRNKTEVDIYNSDPLICRAGLKVC 208 + ++ + N + + + V ++ R + + Sbjct: 147 DYQGGFEQEDLNQLFEAIRSNYKAWCLGFAPLAVGGDMDSIAVQEFSRTLFNMRPDIALS 206 Query: 209 FGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAY 268 G + S + + LP +TVP +LQ D + L + +++ Sbjct: 207 VGQTIFQ--SDMRQILPFVTVPCHILQSVKDLAVPVVVSEYLHANLGC-ESVVEVIPSDG 263 Query: 269 HVLHKELPE-----VTNSVFHEINM 288 H+ P+ + + ++I M Sbjct: 264 HLPQLSSPDSVIPVILRHIRNDIAM 288 >2XMZ-A nrPDB Length = 269 Score = 67.6 bits (163), Expect = 7e-12, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 94/271 (34%), Gaps = 26/271 (9%) Query: 27 GQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGE 86 G ++++ ++ HG S Y V D GHG+ + Sbjct: 1 GHMTHYKFYEANVETNQVLVFLHGFLSDSRTYHNHIEKFTDN-YHVITIDLPGHGEDQSS 59 Query: 87 RMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS 146 +F + +D + Y + L G+SMGG +A+ A + ++L S Sbjct: 60 MDETWNFDY----ITTLLDRILDKYKDKSITLFGYSMGGRVALYYAINGHIPISNLILES 115 Query: 147 PLVLANPESATTFKVLA----AKVLNLVLPNLSLGPIDSSVLSRNKTEVDI--------- 193 E+ + L AKVL++ L + + L +++ E+ + Sbjct: 116 TSPGIKEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQLELPVEIQHQIRQQ 175 Query: 194 -YNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLME 252 + P L+ Q+ N L ++ VP L+L G D + A + Sbjct: 176 RLSQSPHKMAKALRDYGTGQMPNLWP----RLKEIKVPTLILAGEYDEKF-VQIAKKMAN 230 Query: 253 LAKSQDKTLKIYEGAYHVLHKELPEVTNSVF 283 L + K+ H +H E + +++ Sbjct: 231 LIP--NSKCKLISATGHTIHVEDSDEFDTMI 259 >3KXP-A nrPDB Length = 314 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 43/258 (16%), Positives = 91/258 (35%), Gaps = 41/258 (15%) Query: 42 KALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVL 101 L+ HG +S +E L L A D GHG S+ + + + + D+ Sbjct: 68 GPLMLFFHGITSNSAVFEPLMIRLSDR-FTTIAVDQRGHGLSD-KPETGYEANDYADDIA 125 Query: 102 QHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKV 161 + ++ + + L+GHS+G ++ AA+ P +V I Sbjct: 126 GLIRTLARGH----AILVGHSLGARNSVTAAAKYPDLVRSVVAI-----------DFTPY 170 Query: 162 LAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGL----------KVCFGI 211 + + L+ + ++ G + + + P I + Sbjct: 171 IETEALDALEARVNAGSQLFEDIKAVEAYLA--GRYPNIPADAIRIRAESGYQPVDGGLR 228 Query: 212 QLLNAVSRVE-------RALPK---LTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTL 261 L ++ + + +P +T P L+++G + +L + L D + Sbjct: 229 PLASSAAMAQTARGLRSDLVPAYRDVTKPVLIVRGESSKLVSAAALAKTSRLRP--DLPV 286 Query: 262 KIYEGAYHVLHKELPEVT 279 + GA H +++ PE+T Sbjct: 287 VVVPGADHYVNEVSPEIT 304 >3WMR-A nrPDB Length = 315 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 59/314 (18%), Positives = 101/314 (32%), Gaps = 55/314 (17%) Query: 5 SSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARM 64 S P ++P+ + R + K + + HG + Y Sbjct: 18 SKPPSAKGTVPFGQYR---------TWYRVTGDLHSGKPPVVLLHGGPGSTHDYLLAMTS 68 Query: 65 LMGLDLLVFAHDHVGHGQSEGERMVVSDFHV---FVRDVLQHVDSM--QKDYPGLPVFLL 119 L V +D +G+G S DF F ++ ++ + DY L Sbjct: 69 LTEAGWPVVHYDQLGNGGSTHLPEKGEDFWTVQLFEDELDNLLNQLGIAGDY-----VLF 123 Query: 120 GHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPI 179 G S GG + + AA RP G+V+ + P S + A++ L+ P++ + Sbjct: 124 GQSWGGMLGSVHAARRPAGLRGLVVANA-----PASMKIWLQEMARLRALLPPDVQETLL 178 Query: 180 DSSVL----------------------------SRNKTEVDIYNSDPLICRAGLKVCFGI 211 T ++IYN + F + Sbjct: 179 KHEAARTTDTEEYFHAMRAFYDRHVCRIVPWPRDFAATFMEIYNDPTVYTTMNGPNEFHV 238 Query: 212 QLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVL 271 VE LP + VP ++L G D ++L D ++ E + HV Sbjct: 239 IGTLRDWSVEDCLPDIQVPTMVLIGRHDE-ATPATVKPFLDLVP--DVRYEVLENSSHVP 295 Query: 272 HKELPEVTNSVFHE 285 H E PE + V + Sbjct: 296 HLEEPERFHEVMID 309 >3OM8-A nrPDB Length = 266 Score = 65.3 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 49/265 (18%), Positives = 92/265 (34%), Gaps = 16/265 (6%) Query: 18 DLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDH 77 +L L +DG L R K L+ +S+ G ++ L V +D Sbjct: 5 NLSFLATSDGASLAYRL--DGAAEKPLLALSNSIGTTLHMWDAQLPALTRH-FRVLRYDA 61 Query: 78 VGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPG 137 GHG S DVL+ +D+++ LG S+GG + A P Sbjct: 62 RGHGASSV-PPGPYTLARLGEDVLELLDALEVR----RAHFLGLSLGGIVGQWLALHAPQ 116 Query: 138 HFAGMVLISPLVLANPESATTFK---VLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIY 194 +VL + P + + VL A+ ++ ++L R + V+ + Sbjct: 117 RIERLVLANTSAWLGPAAQWDERIAAVLQAEDMSETAAGFLGNWFPPALLERAEPVVERF 176 Query: 195 NSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELA 254 + + + + R + L ++ P L++ G+ D + + L+ Sbjct: 177 RAMLMATNRHGLAGSFAAVRDTDLRAQ--LARIERPTLVIAGAYDTVTAASHGELIAASI 234 Query: 255 KSQDKTLKIYEGAYHVLHKELPEVT 279 L A H+ + E P+ Sbjct: 235 --AGARLVTLP-AVHLSNVEFPQAF 256 >2WUG-A nrPDB Length = 291 Score = 64.9 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 47/251 (18%), Positives = 94/251 (37%), Gaps = 20/251 (7%) Query: 45 IFVSHGAGEHSGRYEELARMLM--GLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 + + HG G + + +R + V A D G+G S+ +R F+ + Sbjct: 39 VVLLHGGGPGAASWTNFSRNIAVLARHFHVLAVDQPGYGHSD-KRAEHGQFNRYAA---M 94 Query: 103 HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISP----LVLANPESATT 158 + + V L+G+++GG A+ A + P +VL+ P + L P+ Sbjct: 95 ALKGLFDQLGLGRVPLVGNALGGGTAVRFALDYPARAGRLVLMGPGGLSINLFAPDPTEG 154 Query: 159 FKVLAAKVLNLVLPN----LSLGPIDSSVLSR---NKTEVDIYNSDPLICRAGLKVCFGI 211 K L+ + N L + D ++++ ++ + L + F Sbjct: 155 VKRLSKFSVAPTRENLEAFLRVMVYDKNLITPELVDQRFALASTPESLTATRAMGKSFAG 214 Query: 212 QLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVL 271 A + R + +L P LL+ G DR+ GA + ++ L ++ H + Sbjct: 215 ADFEAG-MMWREVYRLRQPVLLIWGREDRVNPLDGALVALKTIPRA--QLHVFGQCGHWV 271 Query: 272 HKELPEVTNSV 282 E + N + Sbjct: 272 QVEKFDEFNKL 282 >6AP7-A nrPDB Length = 269 Score = 64.5 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 44/252 (17%), Positives = 88/252 (34%), Gaps = 17/252 (6%) Query: 39 GTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHV--- 95 G+ + ++ ++HG G + + + D V +D V G + + Sbjct: 17 GSGERVLVLAHGFGTDQSAWNRILPFFLR-DYRVVLYDLVCAGSVNPDFFDFRRYTTLDP 75 Query: 96 FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPES 155 +V D+L +D++ D +GHS+ I IL + RP F+ ++LI + Sbjct: 76 YVDDLLHILDALGID----QCAYVGHSVSAMIGILASIRRPELFSKLILIGASPRFLNDE 131 Query: 156 ATT---FKVLAAKVLNLVLPNLSLGPIDSSVLSRN---KTEVDIYNSDPLICRAGLKVCF 209 + KV + + N + L+ V ++ R + + Sbjct: 132 DYHGGFEQGEIEKVFSAMEANYEAWVNGFAPLAVGADVPAAVREFSRTLFNMRPDITLFV 191 Query: 210 GIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH 269 + N S + L + VP + Q + D + A L ++ T+ H Sbjct: 192 SRTVFN--SDMRGVLGLVKVPCHIFQTARDHSVPASVATYLKNHLGGKN-TVHWLNIEGH 248 Query: 270 VLHKELPEVTNS 281 + H P + Sbjct: 249 LPHLSAPTLLAQ 260 >3DYV-A nrPDB Length = 251 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 45/229 (19%), Positives = 74/229 (32%), Gaps = 27/229 (11%) Query: 45 IFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVS-DFHVFVRDVLQH 103 + + H +AR L V+ GHG E ++ + ++ + Sbjct: 25 VVLLHAYTGSPNDMNFMARALQRSGYGVYVPLFSGHGTVEPLDILTKGNPDIWWAESSAA 84 Query: 104 VDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLA 163 V M Y VF+ G S+GG A+ PG AG V SP++ F Sbjct: 85 VAHMTAKY--AKVFVFGLSLGGIFAMKALETLPGITAGGVFSSPILPGKHHLVPGFLKY- 141 Query: 164 AKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERA 223 A+ +N + + L +D + + V Sbjct: 142 AEYMNRLAGKSDESTQILAYLPGQLAAIDQFAT----------------------TVAAD 179 Query: 224 LPKLTVPFLLLQGSADRLCDSKGAYLLMEL-AKSQDKTLKIYEGAYHVL 271 L + P + Q D L D + AY L + + Y+ A HV+ Sbjct: 180 LNLVKQPTFIGQAGQDELVDGRLAYQLRDALINAARVDFHWYDDAKHVI 228 >1CR6-A nrPDB Length = 554 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 63/190 (33%), Gaps = 7/190 (3%) Query: 42 KALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVL 101 + + HG E + L V A D G+G S + + ++L Sbjct: 256 GPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPP----EIEEYAMELL 311 Query: 102 QHVDSMQKDYPGLP-VFLLGHSMGGAIAILTAAERPGHF-AGMVLISPLVLANPESATTF 159 D G+P +GH G + A P A L +P + +P+ + Sbjct: 312 CKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMK 371 Query: 160 KVLAAKVLNLVLPNLSLGPIDSSV-LSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVS 218 + + V N L G ++ + + ++T + + + I + + Sbjct: 372 VIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNT 431 Query: 219 RVERALPKLT 228 + L K+T Sbjct: 432 PEDPNLSKIT 441 >2OCI-A nrPDB Length = 254 Score = 62.2 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 51/257 (19%), Positives = 85/257 (33%), Gaps = 19/257 (7%) Query: 34 YWKPTGTPKALIFVSHG-AGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSD 92 +++ TG + + G G + + L V A D G+G S Sbjct: 15 HYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRP-PDRDFP 73 Query: 93 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN 152 F RD VD M K V LLG S GG A++ AA+ P + MV+ Sbjct: 74 ADFFERDAKDAVDLM-KALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVT 132 Query: 153 PESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTE-VDIYNSDPLICRAGLKVCFGI 211 E + ++ + S +R E + Y+ C + Sbjct: 133 DEDSMIYEGI-------------RDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQF 179 Query: 212 QLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVL 271 + L + LP++ P L++ G D L A + + + L + H L Sbjct: 180 KHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHV--KGSRLHLMPEGKHNL 237 Query: 272 HKELPEVTNSVFHEINM 288 H + N + + Sbjct: 238 HLRFADEFNKLAEDFLQ 254 >3V1K-A nrPDB Length = 286 Score = 61.8 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 52/282 (18%), Positives = 91/282 (32%), Gaps = 34/282 (12%) Query: 23 VNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARM---LMGLDLLVFAHDHVG 79 +N G F ++ G + +I + HG G +G + R + V D G Sbjct: 15 INEKGFSDFNIHYNEAGNGETVIML-HGGGPGAGGWSNYYRNVGPFVDAGYRVILKDSPG 73 Query: 80 HGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHF 139 +S+ M V R V +D++ D L+G+SMGGA A+ A E P Sbjct: 74 FNKSDAVVMDEQRGLVNARAVKGLMDALDID----RAHLVGNSMGGATALNFALEYPDRI 129 Query: 140 AGMVLISP--------LVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRN--KT 189 ++L+ P + FK+ A + L + D S+++ + Sbjct: 130 GKLILMGPGGLGPSMFAPMPMEGIKLLFKLYAEPSYETLKQMLQVFLYDQSLITEELLQG 189 Query: 190 EVDIYNSDP------LICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCD 243 + P LI + V L ++ + G DR Sbjct: 190 RWEAIQRQPEHLKNFLISAQKAPLSTW--------DVTARLGEIKAKTFITWGRDDRFVP 241 Query: 244 SKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHE 285 L+ D L ++ E + N + + Sbjct: 242 LDHGLKLLWNID--DARLHVFSKCGQWAQWEHADEFNRLVID 281 >4NMW-A nrPDB Length = 259 Score = 60.3 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 47/270 (17%), Positives = 86/270 (31%), Gaps = 31/270 (11%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 +W+ G + + HG G ++ + + L + D G+G+S G Sbjct: 8 WWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSH-FTLHLVDLPGYGRSSG--FGAMTL 64 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 V LG S+GG +A A P +V ++ + Sbjct: 65 EEMTAQVA--------KNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFS- 115 Query: 154 ESATTFKVLAAKVLNLVLPNLS------------LGPIDSSVLSRN-KTEVDIYNSDPLI 200 + + + ++L LS L + + ++ +T + + P+ Sbjct: 116 -AREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMP 174 Query: 201 CRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKT 260 + G+++L V + AL + +PFL L G D L K LL L Sbjct: 175 DVE--VLNGGLEILKTVD-LREALKNVNMPFLRLYGYLDGLVPRKIVPLLDTLWPHSTSQ 231 Query: 261 LKIYEGAYHVLHKELPEVTNSVFHEINMWV 290 I A H P + + Sbjct: 232 --IMAKAAHAPFISHPAAFCQALMTLKSSL 259 >1QTR-A nrPDB Length = 317 Score = 59.5 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 45/297 (15%), Positives = 94/297 (31%), Gaps = 47/297 (15%) Query: 26 DGQYLFCRYWKPTGTPKAL-IFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSE 84 D YW+ +G P HG ++ V D G G+S Sbjct: 20 DTGDGHRIYWELSGNPNGKPAVFIHGGPGGGIS-PHHRQLFDPERYKVLLFDQRGCGRSR 78 Query: 85 GERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVL 144 + ++ + ++ ++ +++ + G S G +A+ A P + MVL Sbjct: 79 PHASLDNN-TTW--HLVADIERLREMAGVEQWLVFGGSWGSTLALAYAQTHPERVSEMVL 135 Query: 145 ISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVD-IYNSDPLICRA 203 L ++ A++ + D + ++DP + Sbjct: 136 RGIFTLRKQRLHWYYQDGASRFFPEKWERVLSILSDDERKDVIAAYRQRLTSADPQVQLE 195 Query: 204 GLKVC--FGIQLLN-----------------AVSRVE-----------------RALPKL 227 K+ + + + A +R+E R +P + Sbjct: 196 AAKLWSVWEGETVTLLPSRESASFGEDDFALAFARIENHYFTHLGFLESDDQLLRNVPLI 255 Query: 228 T-VPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVF 283 +P +++ G D C + A+ L + + L I EGA H + P + + + Sbjct: 256 RHIPAVIVHGRYDMACQVQNAWDLAKAWP--EAELHIVEGAGH--SYDEPGILHQLM 308 >1AZW-A nrPDB Length = 313 Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 44/302 (14%), Positives = 93/302 (30%), Gaps = 50/302 (16%) Query: 11 PQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDL 70 P+ PYQ V+ F + P G P + + HG G +++ R Sbjct: 6 PEITPYQQGSLKVDDRHTLYFEQCGNPHGKP---VVMLHGGPG-GGCNDKMRRFHDPAKY 61 Query: 71 LVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAIL 130 + D G G+S D++ ++ ++ + G S G +A+ Sbjct: 62 RIVLFDQRGSGRSTPH---ADLVDNTTWDLVADIERLRTHLGVDRWQVFGGSWGSTLALA 118 Query: 131 TAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNL--SLGPIDSSVLSRNK 188 A P +VL +L E ++ A+++ + ++ P++ + L Sbjct: 119 YAQTHPQQVTELVLRGIFLLRRFELEWFYQEGASRLFPDAWEHYLNAIPPVERADLMSA- 177 Query: 189 TEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERA-------------LPKL-------- 227 + + D A K + + V+ ++ Sbjct: 178 FHRRLTSDDEATRLAAAKAWSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENHYFVNG 237 Query: 228 -----------------TVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHV 270 +P +++ G D +C + A+ L + L+I + H Sbjct: 238 GFFEVEDQLLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKA--QLQISPASGHS 295 Query: 271 LH 272 Sbjct: 296 AF 297 >5UXZ-A nrPDB Length = 307 Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 52/296 (17%), Positives = 97/296 (32%), Gaps = 40/296 (13%) Query: 20 PHLVNADGQYLFCRYWKP-TGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHV 78 PH V G+ + P GTP + HG S + + + A D + Sbjct: 9 PHYVEVLGERMHYVDVGPRDGTP---VLFLHGNPTSSYVWRNIIPHVAPT-HRCIAPDLI 64 Query: 79 GHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGH 138 G G+S+ + + F VR + ++++ + V L+ H G A+ A P Sbjct: 65 GMGKSD-KPDLGYFFDDHVRFMDAFIEALGLE----EVVLVIHDWGSALGFHWAKRNPER 119 Query: 139 FAGMVLISPLVLANPESATTFKVLAAKVLNLVLP-----------------NLSLGPIDS 181 G+ + + + + A + L +G + Sbjct: 120 VKGIAFMEFIRPI--PTWDEWPEFARETFQAFRTTDVGRKLIIDQNVFIEGTLPMGVVRP 177 Query: 182 SVLSRNKTEVDIY----NSDPL--ICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQ 235 + + + +PL ++ V L + VP LL Sbjct: 178 LTEVEMDHYREPFLNPVDREPLWRFPNELPIAGEPANIVALVEEYMDWLHQSPVPKLLFW 237 Query: 236 GSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVS 291 G+ L A L + + K + I G ++L ++ P++ S EI W+S Sbjct: 238 GTPGVLIPPAEAARLAKSLPNC-KAVDIGPGL-NLLQEDNPDLIGS---EIARWLS 288 >5HK8-A nrPDB Length = 298 Score = 56.4 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 44/256 (17%), Positives = 86/256 (33%), Gaps = 16/256 (6%) Query: 34 YWKPTGTPKALI--FVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVS 91 + G + +I HGA + + +L +L + D G G S + +V Sbjct: 36 FMGGEGGAEPVIHFVFVHGASHGAWCWYKLTTLLDAAGFKSTSVDLTGAGISLIDSNIVF 95 Query: 92 DFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLA 151 D + R + + + P V L+GHS+GG + + + ++ + Sbjct: 96 DSDQYNRPLFSLLSDLP---PHHKVILVGHSIGGGSVTEALCKFTDKISMAIYLAAS-MV 151 Query: 152 NPESATTFKVLAAKVLNLVLPNLSLGP---IDSSVLSRNKTEVD--IYNSDPLICRAGLK 206 P S + + V + + G + + + Y+ PL Sbjct: 152 QPGSIPSPHLSNIHVGEEDIWEYTYGEGTDKPPTGVLMKPEFIRHYYYSQSPLEDVTLSS 211 Query: 207 VCFGIQLLNAVSRVERALP---KLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKI 263 + A +++ P VP + ++ + D L DS LL+E L + Sbjct: 212 KLLRPAPMRAFQDLDKLPPNPEAEKVPRVYIKTAKDNLFDSVRQDLLVENWPP--SQLYV 269 Query: 264 YEGAYHVLHKELPEVT 279 E + H +P Sbjct: 270 LEDSDHSAFFSVPTTL 285 >6FKX-A nrPDB Length = 324 Score = 55.6 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 43/267 (16%), Positives = 77/267 (28%), Gaps = 53/267 (19%) Query: 40 TPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGH-----GQSEGERMVVSDF- 93 P + HG +SG + + L V A D G G++ E ++ + Sbjct: 85 EPHPALLQFHGYTGNSGDWSSRL-HYVALGYTVAALDCRGQAGLSVGEAPVENWSMASYL 143 Query: 94 ----HVFVRD-------------VLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP 136 D + Q V +M D V G+S GG + + AA P Sbjct: 144 LRGIDDDAADNLALRHLFLDTARLAQIVLAMD-DVDPDRVAATGYSQGGGLTLACAALEP 202 Query: 137 GHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNS 196 + LA P F + + L I + +R+ + Sbjct: 203 R----------IRLAAP--VYPFLCDFRRAWEMDLEKGPYNEITTYFRARDPRHLR---E 247 Query: 197 DPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKS 256 + + R G V+ P++ L+ AD++C + Sbjct: 248 EEIFSRLGYVD------------VQHLAPRVRAEVLMTVSLADKICPPSTQFAAYNKLGG 295 Query: 257 QDKTLKIYEGAYHVLHKELPEVTNSVF 283 K ++Y H + + Sbjct: 296 P-KDYRLYPDFAHETLPGTDDAIFTFL 321 >5YHP-A nrPDB Length = 355 Score = 54.9 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 42/266 (15%), Positives = 74/266 (27%), Gaps = 49/266 (18%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQ-SEGERMVVSD 92 Y P G P + HG + AR + D G G+ + + + Sbjct: 65 YGNPQGKP---VVFLHGGPGGGAS-DSDARRFNPTTYRIVLFDQRGSGESTPASCLEDNT 120 Query: 93 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN 152 V D+ + + +Q G + G S G +A+ A P + L L Sbjct: 121 TQALVEDIEKIREFLQV---GAAWHVFGGSWGSTLALAYAQAHPARVKSLTLRGIFTLRK 177 Query: 153 ---------PESATTFKVLAAKVLNLVLPNLSLGPI--------DSSVLSRNKTEVDIYN 195 P S+ F + L+ + + S R + Sbjct: 178 KELDFFYQGPGSSFVFPEYWEEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGRAWSR 237 Query: 196 SDPLICR-------------AGLKVCFGI---QLLNAVSRV-------ERALPKLT-VPF 231 + R G F + + K++ +P Sbjct: 238 WEMATSRLHVDPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKISHIPA 297 Query: 232 LLLQGSADRLCDSKGAYLLMELAKSQ 257 +++QG D +C AY L +L Sbjct: 298 VIVQGRYDMVCPITTAYELTKLWPEA 323 >5AOA-A nrPDB Length = 286 Score = 54.5 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 48/280 (17%), Positives = 85/280 (30%), Gaps = 49/280 (17%) Query: 9 RTPQSIPYQD---LPHLVNADGQ-YLFCR-YWKPTGTPKALIFVSHGA--GEHSGRYEEL 61 R P +P + + N D + Y++ WKP A++F G ++ Sbjct: 7 RYPPEMPGAEVKVYKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQ 66 Query: 62 ARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDY-----PGLPV 116 G ++ A D+ + + V D + +++ + Sbjct: 67 CEYFAGRGMVAMAADYRVGSRHNVK------VADCVADAKSAIRWVRQHAAELGVDPQKI 120 Query: 117 FLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSL 176 G S GG +A A V++ L + + + AA + N VL Sbjct: 121 VASGGSAGGHLA-----------ACTVMVPDLEAPEEDHTISSQANAAILFNPVLILSRE 169 Query: 177 GPID-SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQ 235 G D + + ++P + A LP P ++ Sbjct: 170 GLKDHVPRQDWEERLRERLGTEPKAVSP-------YHHIRAG------LP----PMIIFH 212 Query: 236 GSADRLCDSKGAYLLMELAKSQDK--TLKIYEGAYHVLHK 273 G+AD + L E K L +EGA H Sbjct: 213 GTADNTVPFETIRLFAEAMKKAGNRCELVPFEGAAHGFFN 252 >2WFL-A nrPDB Length = 264 Score = 53.7 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 40/114 (35%), Gaps = 3/114 (2%) Query: 46 FVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD 105 + HG + + +L +L V A D G + + + H F ++ Sbjct: 14 VLVHGGCLGAWIWYKLKPLLESAGHKVTAVDLSAAGINPRR---LDEIHTFRDYSEPLME 70 Query: 106 SMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTF 159 M P V LLGHS GG L P + V +S ++ S T Sbjct: 71 VMASIPPDEKVVLLGHSFGGMSLGLAMETYPEKISVAVFMSAMMPDPNHSLTYP 124 >3V48-A nrPDB Length = 268 Score = 53.7 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 36/251 (14%), Positives = 85/251 (33%), Gaps = 15/251 (5%) Query: 37 PTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVF 96 P ++ + G G + +L + V +D G G + Sbjct: 10 PPYADAPVVVLISGLGGSGSYWLPQLAVL-EQEYQVVCYDQRGTGNNPDTLAEDYSIAQM 68 Query: 97 VRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESA 156 ++ Q + + ++ ++GH++G + + A + P ++ ++ + N + Sbjct: 69 AAELHQALVAAGIEHYA----VVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTR 124 Query: 157 TTFKVLAAKVLN----LVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQ 212 F+V + + + L + ++ ++ ++ L G Sbjct: 125 RCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRR- 183 Query: 213 LLNAVSRVE--RALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHV 270 LNA+ R + ++ P ++ S D L + + L K + Y G H Sbjct: 184 -LNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGG--HA 240 Query: 271 LHKELPEVTNS 281 + PE N+ Sbjct: 241 CNVTDPETFNA 251 >4CCY-A nrPDB Length = 296 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 41/253 (16%), Positives = 79/253 (31%), Gaps = 36/253 (14%) Query: 43 ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 + + HG S + +A D +G + + + S D + Sbjct: 55 PSLILLHGGLFSSAMWYPNIAAWSS-QFRTYAVDIIG----DKNKSIPSAAMETRADFAE 109 Query: 103 HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVL 162 + + L G S+GG+ + P V+ISP Sbjct: 110 WMKDVFDSLGLETAHLAGLSLGGSHIVNFLLRAPERVERAVVISP--------------- 154 Query: 163 AAKVLNLVLPNLSLGPIDSSVLSRNKTEV-----DIYNSDPLICRAGLKVCFG----IQL 213 A+ P++ + + ++ + D Y+ PL+ R + L Sbjct: 155 -AEAFISFHPDVYKYAAELTGARGAESYIKWITGDSYDLHPLLQRQIVAGVEWQDEQRSL 213 Query: 214 LNAVS-----RVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAY 268 + ++ L + VP LL+ G + + + A+ +I + A Sbjct: 214 KPTENGFPYVFTDQELKSIQVPVLLMFGEHEAMYHQQMAFERAS-VLVPGIQAEIVKNAG 272 Query: 269 HVLHKELPEVTNS 281 H+L E PE N Sbjct: 273 HLLSLEQPEYVNQ 285 >4IH4-A nrPDB Length = 267 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 45/254 (17%), Positives = 86/254 (33%), Gaps = 17/254 (6%) Query: 39 GTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHV--- 95 GT ++F++HG G + + V +D V G + + + Sbjct: 16 GTGDRILFLAHGFGTDQSAWHLILPYFTQN-YRVVLYDLVCAGSVNPDYFDFNRYTTLDP 74 Query: 96 FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPES 155 +V D+L VDS+ +GHS+ I I+ + RP F+ ++LI + Sbjct: 75 YVDDLLNIVDSLGIQ----NCAYVGHSVSAMIGIIASIRRPELFSKLILIGFSPRFLNDE 130 Query: 156 ATT---FKVLAAKVLNLVLPNLSLGPIDSSVLSRN---KTEVDIYNSDPLICRAGLKVCF 209 + KV + + N + L+ V ++ R + + Sbjct: 131 DYHGGFEEGEIEKVFSAMEANYEAWVHGFAPLAVGADVPAAVREFSRTLFNMRPDISLFV 190 Query: 210 GIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH 269 + N S + L + VP ++Q + D + A L D T++ + H Sbjct: 191 SRTVFN--SDLRGVLGLVRVPTCVIQTAKDVSVPASVAEYLRSHLGG-DTTVETLKTEGH 247 Query: 270 VLHKELPEVTNSVF 283 + P Sbjct: 248 LPQLSAPAQLAQFL 261 >1Y7H-A nrPDB Length = 268 Score = 52.6 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 45/112 (40%), Gaps = 3/112 (2%) Query: 46 FVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD 105 + HGA + +L +L V A D G + + + + +++ ++ Sbjct: 8 VLVHGACHGGWSWYKLKPLLEAAGHKVTALDLAASGTDLRKIEELRTLYDYTLPLMELME 67 Query: 106 SMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESAT 157 S+ D V L+GHS+GG L + P V ++ + + +++ Sbjct: 68 SLSAD---EKVILVGHSLGGMNLGLAMEKYPQKIYAAVFLAAFMPDSVHNSS 116 >3FCY-A nrPDB Length = 346 Score = 52.6 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 32/257 (12%), Positives = 74/257 (28%), Gaps = 21/257 (8%) Query: 21 HLVNADGQYLFCRYWKPTGTPK-ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVG 79 + G + +Y KP K + HG +SG + + + V A D G Sbjct: 86 YFTGVRGARIHAKYIKPKTEGKHPALIRFHGYSSNSGDWNDKLNYVA-AGFTVVAMDVRG 144 Query: 80 HG--QSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG--GAIAILTAAER 135 G + + + + + + D + + I + Sbjct: 145 QGGQSQDVGGVTGNTLN------GHIIRGLDDDADNMLFRHIFLDTAQLAGIVMNMPEVD 198 Query: 136 PGHFAGMVLI--SPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDI 193 M L LA + + ++ + + +D + + D Sbjct: 199 EDRVGVMGPSQGGGLSLACAALEPRVRKVVSE-YPFLSDYKRVWDLDL-AKNAYQEITDY 256 Query: 194 YNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMEL 253 + +V + ++ + ++ L+ G D++C + Sbjct: 257 FRLFDPRHERENEVFTKLGYIDVKN----LAKRIKGDVLMCVGLMDQVCPPSTVFAAYNN 312 Query: 254 AKSQDKTLKIYEGAYHV 270 +S+ K +K+Y H Sbjct: 313 IQSK-KDIKVYPDYGHE 328 >1M33-A nrPDB Length = 258 Score = 52.6 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 45/267 (16%), Positives = 82/267 (30%), Gaps = 29/267 (10%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 +W+ G + + HG G ++ + + L + D G G+S G Sbjct: 5 WWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSH-FTLHLVDLPGFGRSRG--FGALSL 61 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 VLQ LG S+GG +A A P +V ++ + Sbjct: 62 ADMAEAVLQQA--------PDKAIWLGWSLGGLVASQIALTHPERVRALVTVASSPCFSA 113 Query: 154 ESATTFKVLAAKVLNLVLPNLS------------LGPIDSSVLSRNKTEVDIYNSDPLIC 201 + VL LS L + + ++ + + + Sbjct: 114 RDEW--PGIKPDVLAGFQQQLSDDQQRTVERFLALQTMGTETARQDA--RALKKTVLALP 169 Query: 202 RAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTL 261 + V G + + + L +++PFL L G D L K +L +L + Sbjct: 170 MPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSES-- 227 Query: 262 KIYEGAYHVLHKELPEVTNSVFHEINM 288 I+ A H P + + Sbjct: 228 YIFAKAAHAPFISHPAEFCHLLVALKQ 254 >3O4I-A nrPDB Length = 582 Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 46/115 (40%), Gaps = 5/115 (4%) Query: 40 TPKALIFVSHGAG--EHSGRYEELARMLMGLDLLVFAHDHV---GHGQSEGERMVVSDFH 94 TP + + HG E S ++ A L V ++ G+G+ +++ Sbjct: 358 TPGPTVVLVHGGPFAEDSDSWDTFAASLAAAGFHVVMPNYRGSTGYGEEWRLKIIGDPCG 417 Query: 95 VFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLV 149 + DV ++ ++++G+S GG + + +PG F V + +V Sbjct: 418 GELEDVSAAARWARESGLASELYIMGYSYGGYMTLCALTMKPGLFKAGVAGASVV 472 >3P2M-A nrPDB Length = 330 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 41/252 (16%), Positives = 78/252 (30%), Gaps = 19/252 (7%) Query: 38 TGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFV 97 G + HG G+++ ++ + L A D GHG S + Sbjct: 77 WGGSAPRVIFLHGGGQNAHTWDTVIVGL---GEPALAVDLPGHGHSAWREDGNYSPQLNS 133 Query: 98 RDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLA---NPE 154 + + ++ F++G S+GG AI AA P +VL+ A + E Sbjct: 134 ETLAPVL----RELAPGAEFVVGMSLGGLTAIRLAAMAPDLVGELVLVDVTPSALQRHAE 189 Query: 155 SATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFG---- 210 + A + +D ++ + +V L Sbjct: 190 LTAEQRGTVALMHGEREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRY 249 Query: 211 --IQLLNAVSRVERALPKLTVP-FLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGA 267 I+ + + + L+ P L+ GS+ + D A L + + G Sbjct: 250 DAIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRGVHIVEKSG- 308 Query: 268 YHVLHKELPEVT 279 H + + P Sbjct: 309 -HSVQSDQPRAL 319 >4NZZ-A nrPDB Length = 320 Score = 51.0 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 41/292 (14%), Positives = 79/292 (27%), Gaps = 40/292 (13%) Query: 18 DLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDH 77 ++ + Y+ + L+ HG + S + D A D Sbjct: 37 QYINVNGVNLHYI-------SKGQGELMLFLHGFPDFSHIWRHQIDEFS-NDFHTVALDL 88 Query: 78 VGHGQSE-GERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP 136 G+ SE + + V V D+ Q ++ + Y + + H G I A P Sbjct: 89 RGYNLSEKPSGLESYEIDVLVEDIRQVIEGLG--YSSCTLVV--HDWGAGIGWTFAYRYP 144 Query: 137 GHFAGMV-LISPLVLA-NPESATTFKVLAAKVLNLVLPNLSLGP-------------IDS 181 + ++ P E T A + + Sbjct: 145 EYVQKLIAFNGPHPYTFMRELRTNKNQQKASEYMKWFQKQEVQDYMERDNFSGLRKLVID 204 Query: 182 SVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPK----------LTVPF 231 + + D + G + N E L + L +P Sbjct: 205 PGVKKGYLTADDVQAYMNSWENGSVLSMLSYYRNLKIFTEEDLRRKSLFPLEEEVLNIPV 264 Query: 232 LLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVF 283 ++ G+ D + + E + ++ A H E P+ N+V Sbjct: 265 QIIWGNQDPTFMPENLDGIEEYVP--NISVHRLAEASHAPQHEKPQEVNNVM 314 >3KSR-A nrPDB Length = 290 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 39/201 (19%), Positives = 66/201 (32%), Gaps = 15/201 (7%) Query: 36 KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGH-GQSEGERMVVS--D 92 PTG P + HG G AR +GL + D GH G + + V + Sbjct: 24 TPTGMPG--VLFVHGWGGSQHHSLVRAREAVGLGCICMTFDLRGHEGYASMRQSVTRAQN 81 Query: 93 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN 152 Q D + V G S GG ++ L ERP + + L SP + + Sbjct: 82 LDDIKAAYDQLASLPYVDAHSIAVV--GLSYGGYLSALLTRERPVEW--LALRSPALYKD 137 Query: 153 PESATTFKVLAA-KVLNLVLPNLSLGPIDSSVLSRNKTEVDIY----NSDPLICRAGLKV 207 L A L + ++ + + + D+ +D ++ ++ Sbjct: 138 AHWDQPKVSLNADPDLMDYRRRALAPGDNLALAACAQYKGDVLLVEAENDVIVPHPVMRN 197 Query: 208 CFGIQLLNAVSRVERALPKLT 228 + NA S R + Sbjct: 198 -YADAFTNARSLTSRVIAGAD 217 >3BF8-A nrPDB Length = 255 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 48/259 (18%), Positives = 87/259 (33%), Gaps = 32/259 (12%) Query: 45 IFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHV 104 I + HG LAR L+ D + D HG S E ++ ++ +D++ + Sbjct: 19 IVLVHGLFGSLDNLGVLARDLV-NDHNIIQVDVRNHGLSPREPVM--NYPAMAQDLVDTL 75 Query: 105 DSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAA 164 D+ Q D +GHSMGG + A P +V I + + ++ AA Sbjct: 76 DAQQID----KATFIGHSMGGKAVMALTALAPDRIDKLVAID-IAPVDYHVRRHDEIFAA 130 Query: 165 KVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPL--ICRAGLKVCFGI--------QLL 214 +N V + + ++ + R N + + Q Sbjct: 131 --INAVSESDAQTRQQAAAIMR-----QHLNEEGVIQFLLKSFVDGEWRFNVPVLWDQYP 183 Query: 215 NAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKE 274 + V +P P L + G + L+ + GA H +H E Sbjct: 184 HIVGW--EKIPAWDHPALFIPGGNSPYVSEQYRDDLLAQFPQARAHV--IAGAGHWVHAE 239 Query: 275 LPEVTNSVFHEINMWVSQR 293 P ++V I +++ Sbjct: 240 KP---DAVLRAIRRYLNDH 255 >4NVR-A nrPDB Length = 307 Score = 49.9 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 34/224 (15%), Positives = 64/224 (28%), Gaps = 33/224 (14%) Query: 39 GTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQS--EGERMVVSDFH-- 94 G+ L+ + HG ++ + ++A L V D G+G S + Sbjct: 38 GSGSPLVLL-HGHPQNHTTWRKVAPTLAQN-HTVILPDLRGYGDSDKPTSDPAHRTYSKR 95 Query: 95 VFVRDVLQHVDSMQKDYPGLPVFLL-GHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 +D++ +D++ G F GH GG + A + P I A Sbjct: 96 TMAQDIVMLMDAL-----GFSRFAFVGHDRGGRVGHRLALDYPDRVTCCTFIDIAPTATM 150 Query: 154 ESATT---------------FKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSD- 197 + T L ++ I + T + +N Sbjct: 151 YALTDKSFATRYFWWFFLIQPFPLPETMIAHDPAFFLRKHISGQLKIEGATSQEAFNEYL 210 Query: 198 -----PLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQG 236 P + A + ++ ++ P LL G Sbjct: 211 RCYQNPEMIHAICEDYRAAATIDLDDDAADTSARIRCPLQLLWG 254 >1SCK-A nrPDB Length = 257 Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 43/122 (35%), Gaps = 3/122 (2%) Query: 46 FVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD 105 + H + + +L +L L V A D G + + F + +L ++ Sbjct: 7 VLIHTICHGAWIWHKLKPLLEALGHKVTALDLAASGVDPRQIEEIGSFDEYSEPLLTFLE 66 Query: 106 SMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAK 165 ++ PG V L+G S GG + A + A V + ++ + + Sbjct: 67 ALP---PGEKVILVGESCGGLNIAIAADKYCEKIAAAVFHNSVLPDTEHCPSYVVDKLME 123 Query: 166 VL 167 V Sbjct: 124 VF 125 >1R3D-A nrPDB Length = 264 Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 36/98 (36%), Gaps = 14/98 (14%) Query: 43 ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 L+ + HG ++ + L D GHG + + + Sbjct: 17 PLVVLVHGLLGSGADWQPVLSHLARTQCAALTLDLPGHGTNP---------ERHCDNFAE 67 Query: 103 HVDSMQKDYPG-----LPVFLLGHSMGGAIAILTAAER 135 V+ +++ +PV L+G+S+GG + + A+ Sbjct: 68 AVEMIEQTVQAHVTSEVPVILVGYSLGGRLIMHGLAQG 105 >2Y6V-A nrPDB Length = 398 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 42/184 (22%), Positives = 64/184 (34%), Gaps = 19/184 (10%) Query: 5 SSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARM 64 S PR ++ D L + T T L+F+ HG+G +E Sbjct: 16 SWPRAPQSTLCATDRLELTYDVYTSAERQRRSRTATRLNLVFL-HGSGMSKVVWEYYLPR 74 Query: 65 LMGLDLL-------VFAHDHVGHGQSEGERM--VVSDFH--VFVRDVLQHVDSMQKDYPG 113 L+ D V D V HG S + ++F+ RDVL+ Sbjct: 75 LVAADAEGNYAIDKVLLIDQVNHGDSAVRNRGRLGTNFNWIDGARDVLKIATCELGSIDS 134 Query: 114 LPV--FLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVL 171 P ++GHSMGG A+ +P F ++LI P+V+ L Sbjct: 135 HPALNVVIGHSMGGFQALACDVLQPNLFHLLILIEPVVITRKAIGAGRPGLP-----PDS 189 Query: 172 PNLS 175 P + Sbjct: 190 PQIP 193 >2RON-A nrPDB Length = 242 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 52/256 (20%), Positives = 94/256 (36%), Gaps = 33/256 (12%) Query: 38 TGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFV 97 + K + AG +S + L L G + A + GHG ++ + Sbjct: 9 DASEKTQLICFPFAGGYSASFRPLHAFLQGE-CEMLAAEPPGHGTNQTSAIE-------- 59 Query: 98 RDVLQHVDSMQKDY---PGLPVFLLGHSMGGAIAILTAA--ERPGHFAGMVLISPLVLAN 152 D+ + D +++ P P L GHSMGG I A ER G F V+IS + + Sbjct: 60 -DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAIQPPH 118 Query: 153 PESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQ 212 + + + L+ + + LG + + ++ NK + + F Sbjct: 119 IQRKKVSHLPDDQFLDHI---IQLGGMPAELV-ENKEVMSFF-----------LPSFRSD 163 Query: 213 LLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLH 272 L ++ P + G D+ C + A + A +D T ++G + L Sbjct: 164 YRALEQFELYDLAQIQSPVHVFNGLDDKKC-IRDAEGWKKWA--KDITFHQFDGGHMFLL 220 Query: 273 KELPEVTNSVFHEINM 288 + EV +F +N Sbjct: 221 SQTEEVAERIFAILNQ 236 >4CCW-A nrPDB Length = 299 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 44/240 (18%), Positives = 76/240 (31%), Gaps = 10/240 (4%) Query: 43 ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 + + HGA S + +A D +G + + +L Sbjct: 55 PPLVLLHGALFSSTMWYPNIADWSSK-YRTYAVDIIGDKNKSIPENLSGTRTDYANWLLD 113 Query: 103 HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANP-ESATTFKV 161 D++ + ++G S+GG + P ++SP P Sbjct: 114 VFDNLGIE----KSHMIGLSLGGLHTMNFLLRMPERVKSAAILSPAETFLPFHHDFYKYA 169 Query: 162 LAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVE 221 L N V L+ D +VL V + + ++ + G + + Sbjct: 170 LGLTASNGVEKFLNWMMTDQNVLH--PIFVKQFQA-GVMWQDGSRNPNPKADGFPYVFTD 226 Query: 222 RALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNS 281 L VP LLL G + + D A L + D ++ + A HVL E P N Sbjct: 227 EELRSARVPILLLLGEHEVIYDPHSA-LHRASSFVPDIEAEVIKNAGHVLSMEQPAYVNE 285 >1Q0R-A nrPDB Length = 298 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 44/262 (16%), Positives = 81/262 (30%), Gaps = 40/262 (15%) Query: 43 ALIFVSHGAGEHSGRY-EELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF--HVFVRD 99 + + G + + +E AR L L V +DH G+S + D Sbjct: 24 PALLLVMGGNLSALGWPDEFARRLADGGLHVIRYDHRDTGRSTTRDFAAHPYGFGELAAD 83 Query: 100 VLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGM-VLISPLVLANPESATT 158 + +D D ++G SMG I + A + + + +L+ + + ++ Sbjct: 84 AVAVLDGWGVD----RAHVVGLSMGATITQVIALDHHDRLSSLTMLLGGGLDIDFDANIE 139 Query: 159 FKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTE--------------------VDIYNSDP 198 + L+ LP +D+ L E V +++ Sbjct: 140 RVMRGEPTLDG-LPGPQQPFLDALALMNQPAEGRAAEVAKRVSKWRILSGTGVPFDDAEY 198 Query: 199 LICRAGLKVCFGIQLLNAVSRVERALP---------KLTVPFLLLQGSADRLCDSKGAYL 249 G L + LP ++TVP L++Q D + + Sbjct: 199 ARWEERAIDHAGGVLAEPYAHYSLTLPPPSRAAELREVTVPTLVIQAEHDPIAPAPHGKH 258 Query: 250 LMELAKSQDKTLKIYEGAYHVL 271 L L + L G H L Sbjct: 259 LAGLIPTA--RLAEIPGMGHAL 278 >4GDM-A nrPDB Length = 268 Score = 47.2 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 41/113 (36%), Gaps = 9/113 (7%) Query: 35 WKPTGTPK-ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 G P + HG ++E+ D D GHG S + D Sbjct: 22 QAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFA--DYSRLYVDLPGHGGSAAISVDGFD- 78 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS 146 DV + Y L +L+G+S+GG +A++ A + G+++ Sbjct: 79 -----DVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEG 126 >2PSJ-A nrPDB Length = 319 Score = 46.8 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 34/115 (29%), Gaps = 4/115 (3%) Query: 29 YLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERM 88 F Y+ + + HG S + + + + D +G G+S Sbjct: 31 DSFINYYDSEKHAENAVIFLHGNATSSYLWRHVVPHIEPVA-RCIIPDLIGMGKSGK--- 86 Query: 89 VVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMV 143 + + + + + +GH G A+A A E +V Sbjct: 87 SGNGSYRLLDHYKYLTAWFELLNLPKKIIFVGHDWGAALAFHYAYEHQDRIKAIV 141 >4G5X-A nrPDB Length = 279 Score = 46.4 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 34/243 (13%), Positives = 67/243 (27%), Gaps = 3/243 (1%) Query: 41 PKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDV 100 A + + HG + +G V A D GHG+S + Sbjct: 23 EGAPLLMIHGNSSSGAIFAPQLEGEIGKKWRVIAPDLPGHGKSTDAIDPDRSYS-MEGYA 81 Query: 101 LQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFK 160 + MQ + G S+GG I I A P M+ +P V Sbjct: 82 DAMTEVMQ-QLGIADAVVFGWSLGGHIGIEMIARYPEMRGLMITGTPPVAREEVGQGFKS 140 Query: 161 VLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRV 220 + + + + E + + ++ F Sbjct: 141 GPDMALAGQEIFSERDVESYARSTCGEPFEASLLDIVARTDGRARRIMFEKFGSGTGGNQ 200 Query: 221 ERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTN 280 + + +P ++ G + + + + KT + + A H +E P + Sbjct: 201 RDIVAEAQLPIAVVNGRDEPFVELDFVSKVKFGNLWEGKT-HVIDNAGHAPFREAPAEFD 259 Query: 281 SVF 283 + Sbjct: 260 AYL 262 >3WYD-A nrPDB Length = 228 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 29/152 (19%), Positives = 47/152 (30%), Gaps = 22/152 (14%) Query: 27 GQYLFCRYWKPTGTPK----ALIFVSHGAGEHSGRYEE------LARMLMGLDLLVFAHD 76 G ++ R + PT L+ HG G Y + +V Sbjct: 18 GSHMPYRLYVPTTYDGTKAFPLVIALHGMGGDENSYFDSYQRGAFMIEAENRGYIVACPK 77 Query: 77 HVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLP--VFLLGHSMGGAIAILTAAE 134 RDV+ + +++DY P +++ GHSMGG A Sbjct: 78 GRQPASMYVGPAE--------RDVMDVIAEVRRDYKIDPDRIYMTGHSMGGYGTWSIAMN 129 Query: 135 RPGHFAGMVLISPLVLANPESATTFKVLAAKV 166 P FA + ++ NP + V Sbjct: 130 HPDVFAALAPVAG--GGNPLGMANIAHIPQLV 159 >2O2H-A nrPDB Length = 300 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 44/147 (29%), Gaps = 6/147 (4%) Query: 15 PYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFA 74 PY P + G+ + I HG S + + L GL + A Sbjct: 8 PYGQ-PKYLEIAGKRMAYIDEGK----GDAIVFQHGNPTSSYLWRNIMPHLEGLG-RLVA 61 Query: 75 HDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAE 134 D +G G S+ D + + G V L+ H G A+ A + Sbjct: 62 CDLIGMGASDKLSPSGPDRYSYGEQRDFLFALWDALDLGDHVVLVLHDWGSALGFDWANQ 121 Query: 135 RPGHFAGMVLISPLVLANPESATTFKV 161 G+ + +V + V Sbjct: 122 HRDRVQGIAFMEAIVTPMTWADWPPAV 148 >2YYS-A nrPDB Length = 286 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 41/263 (15%), Positives = 70/263 (26%), Gaps = 23/263 (8%) Query: 41 PKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQS--EGERMVVSDFHVFVR 98 +FV HG + V D G G+S + + V Sbjct: 24 EGPALFVLHGGPGGNAYVLREGLQDYLEGFRVVYFDQRGSGRSLELPQDPRLFTVDALVE 83 Query: 99 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISP--------LVL 150 D L +++ + G LL H G +A+ P G +L++P L Sbjct: 84 DTLLLAEALGVERFG----LLAHGFGAVVALEVLRRFP-QAEGAILLAPWVNFPWLAARL 138 Query: 151 ANPESATTFKVL---AAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKV 207 A + L P + + ++ + Sbjct: 139 AEAAGLAPLPDPEENLKEALKREEPKALFDRLMFPTPRGRMAYEWLAEGAGILGSDAPGL 198 Query: 208 CFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGA 267 F L + P+ P +L G D + L +++ A Sbjct: 199 AFLRNGLWRLDYTPYLTPE-RRPLYVLVGERDGTSYPYAEEVASRL----RAPIRVLPEA 253 Query: 268 YHVLHKELPEVTNSVFHEINMWV 290 H L + PE F E + Sbjct: 254 GHYLWIDAPEAFEEAFKEALAAL 276 >3NWO-A nrPDB Length = 330 Score = 44.1 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 56/320 (17%), Positives = 94/320 (29%), Gaps = 58/320 (18%) Query: 12 QSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRY-EELARMLMGLDL 70 +++P+ D V + P + V HG + Y +A + Sbjct: 31 RTVPFGDHETWVQVTTPENAQPHALP-------LIVLHGGPGMAHNYVANIAALADETGR 83 Query: 71 LVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFL-LGHSMGGAIAI 129 V +D VG G S +DF + + G+ + LG S GG + Sbjct: 84 TVIHYDQVGCGNSTHLPDAPADF--WTPQLFVDEFHAVCTALGIERYHVLGQSWGGMLGA 141 Query: 130 LTAAERP-GHFAGMVLISPLVL-------------------------ANPESATTFKVL- 162 A +P G + + SP + + T L Sbjct: 142 EIAVRQPSGLVSLAICNSPASMRLWSEAAGDLRAQLPAETRAALDRHEAAGTITHPDYLQ 201 Query: 163 -AAKVLNLVLPNLSLGPIDSS----VLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAV 217 AA+ + + P D + + T N G + Sbjct: 202 AAAEFYRRHVCRVVPTPQDFADSVAQMEAEPTVYHTMNGPNEFHVVGTLGDW-------- 253 Query: 218 SRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPE 277 V LP +T P L++ G D K ++ D ++ G H H E PE Sbjct: 254 -SVIDRLPDVTAPVLVIAGEHDE-ATPKTWQPFVDHIP--DVRSHVFPGTSHCTHLEKPE 309 Query: 278 VTNSVFHEINMWVSQRTATA 297 +V + ++ Q A Sbjct: 310 EFRAV---VAQFLHQHDLAA 326 >1DWO-A nrPDB Length = 262 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 43/125 (34%), Gaps = 6/125 (4%) Query: 46 FVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD 105 + H + + +L L V A D G + ++ F + +L ++ Sbjct: 11 VLIHTICHGAWIWHKLKPALERAGHKVTALDMAASGIDPRQIEQINSFDEYSEPLLTFLE 70 Query: 106 SMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAK 165 + + G V ++G S G + A A V + L+ P++ + K Sbjct: 71 KLPQ---GEKVIIVGESCAGLNIAIAADRYVDKIAAGVFHNSLL---PDTVHSPSYTVEK 124 Query: 166 VLNLV 170 +L Sbjct: 125 LLESF 129 >6COB-A nrPDB Length = 260 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 42/123 (34%), Gaps = 3/123 (2%) Query: 46 FVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD 105 + H A + + +L +L V A + G V + + +++ + Sbjct: 8 VLVHNACHGAWIWYKLKPLLESAGHRVTAVELAASGIDPRPIQAVETVDEYSKPLIETLK 67 Query: 106 SMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAK 165 S+ ++ V L+G S GG L A P +V ++ + + + Sbjct: 68 SLPEN---EEVILVGFSFGGINIALAADIFPAKIKVLVFLNAFLPDTTHVPSHVLDKLME 124 Query: 166 VLN 168 + Sbjct: 125 MFG 127 >5YP1-A nrPDB Length = 745 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 51/150 (34%), Gaps = 22/150 (14%) Query: 19 LPHLVNADGQY-LFCRYWKPTG----TPKALIFVSHG----------AGEHSGRYEELAR 63 L ADG L KP G ++ +G S + Sbjct: 492 YGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQ-- 549 Query: 64 MLMGLDLLVFAHDHVG---HGQSEGERMVVSDFHVFVRDVLQHVDSMQKDY--PGLPVFL 118 L +VF D+ G G + G + V V D L+ ++ ++ + + Sbjct: 550 YLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGV 609 Query: 119 LGHSMGGAIAILTAAERPGHFAGMVLISPL 148 G S GG + ++ A+ +A V +P+ Sbjct: 610 YGWSNGGYMTLMLLAKHDEAYACGVAGAPV 639 >3A2L-A nrPDB Length = 309 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 6/108 (5%) Query: 43 ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 ++ HG S + + ++ + A D +G GQS G+ + F VR + Sbjct: 30 PVVLFLHGNPTSSHIWRNILPLVSPVAH-CIAPDLIGFGQS-GKPDIAYRFFDHVRYLDA 87 Query: 103 HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVL 150 ++ +L+ G A+A AA RP G+ + + Sbjct: 88 FIE----QRGVTSAYLVAQDWGTALAFHLAARRPDFVRGLAFMEFIRP 131 >6FVJ-A nrPDB Length = 261 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 32/253 (12%), Positives = 78/253 (30%), Gaps = 24/253 (9%) Query: 43 ALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 +++ AG + Y +R + H +S + ++ Sbjct: 29 PTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSGLPPLE--SIPTLADEIFA 86 Query: 103 HVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPG---HFAGMVLISPLVLANPESATTF 159 + + PV GHSMGG +A A + + + Sbjct: 87 MMKPSARIDD--PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQ 144 Query: 160 KVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSR 219 + ++L+L + ++ + ++ V L ++ + S Sbjct: 145 DLSDREMLDLFT---RMTGMNPDFFTDDEFFV-----------GALPTLRAVRAIAGYSC 190 Query: 220 VERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVT 279 KL+ P G D + +++ +++++ G + L+ LPE+ Sbjct: 191 PPET--KLSCPIYAFIGDKDWIATQDDMDP-WRDRTTEEFSIRVFPGDHFYLNDNLPELV 247 Query: 280 NSVFHEINMWVSQ 292 + + + W + Sbjct: 248 SDIEDKTLQWHDR 260 >1UFO-A nrPDB Length = 238 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 48/138 (34%), Gaps = 14/138 (10%) Query: 40 TPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSD------- 92 PKAL+ HG L L+ A D HG+ EG Sbjct: 22 APKALLLALHGLQGSKEHILALLPGYAERGFLLLAFDAPRHGEREGPPPSSKSPRYVEEV 81 Query: 93 ---FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIA--ILTAAERPGHFAGMVLIS- 146 F + + + ++ + GLP+FL G S+G +A +L RP + Sbjct: 82 YRVALGFKEEARRVAEEAERRF-GLPLFLAGGSLGAFVAHLLLAEGFRPRGVLAFIGSGF 140 Query: 147 PLVLANPESATTFKVLAA 164 P+ L + VLA Sbjct: 141 PMKLPQGQVVEDPGVLAL 158 >4QLA-A nrPDB Length = 447 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 46/292 (15%), Positives = 86/292 (29%), Gaps = 26/292 (8%) Query: 18 DLPHL-VNADGQYLFCRYWKPT---GTPKALIFVSHGAGEHSGRYEELARMLMGL----- 68 PH N G + P G + + HG + E L + Sbjct: 103 QYPHFKTNIQGLNIHFMRITPKVPKGVEIVPLLLLHGWPGSVREFYEAIPHLTAVSKDRN 162 Query: 69 -DLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAI 127 L + A G+G S+ + + + G +G A+ Sbjct: 163 FALEIIAPSLPGYGFSDAAVRPGLAAAEVAVIFKNLMARLGYKQYYVQGGDWGALIGSAM 222 Query: 128 AILTAAE---RPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVL 184 A E + A + + L + ++ ++ N + P S L Sbjct: 223 ATFFPKEIIGFHSNMALTLSPAATFLEFVGALFPSLIVEPELANRLYPLSE----KYSTL 278 Query: 185 SRNKTEVDIYNSDPLICRAGL---KVCFGIQLLNAVSR-VERALPKLTVPFLLLQGSADR 240 + I + P GL +L S L L + + D+ Sbjct: 279 LEELGYMHIQATKPDTVGIGLTDSPAGLLAYILEKFSTWTNPDLRSKEDGGLSYRWTKDQ 338 Query: 241 LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQ 292 L D +L KS ++++Y ++ H +L + + ++ WV Q Sbjct: 339 LID---NLMLYWSTKSIVTSMRLYAESFSSRHFDLK--LDEIQVQVPTWVLQ 385 >5XB6-A nrPDB Length = 306 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 45/261 (17%), Positives = 81/261 (31%), Gaps = 25/261 (9%) Query: 31 FCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVV 90 F + T +A++ G G A+ L + A+D G+S GE + Sbjct: 24 FPPKFDETRQYQAIVLSHPGGGVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQL 83 Query: 91 SDFHVFVRDVLQHVDSMQ--KDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPL 148 + ++ D+ +D + + +G G A + + +S + Sbjct: 84 ENPYIRTEDISAVIDYLTTLSYVDNTRIGAMGICAGAGYTANAAIQDR-RIKAIGTVSAV 142 Query: 149 VLANP---ESATTFKVLAAKVLNLVLPNLSLGPI--------------DSSVLSRNKTEV 191 + + K + A N I +S + + Sbjct: 143 NIGSIFRNGWENNVKSIDALPYVEAGSNARTSDISSGEYAIMPLAPMKESDAPNEELRQA 202 Query: 192 DIYNSDPLICRAGLKVCFGIQLLNAVSRVE---RALPKLTVPFLLLQGSADRLCDSKGAY 248 Y P ++ LN + + A LT P ++ GS + + Sbjct: 203 WEYYHTPRAQYPTAPGYATLRSLNQIITYDAYHMAEVYLTQPTQIVAGS--QAGSKWMSD 260 Query: 249 LLMELAKSQDKTLKIYEGAYH 269 L + A SQDK I EGA H Sbjct: 261 DLYDRASSQDKRYHIVEGANH 281 >2EDA-A nrPDB Length = 310 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 24/175 (13%), Positives = 55/175 (31%), Gaps = 25/175 (14%) Query: 15 PYQDLPHLVNADGQYLFCRYWKPTGTPKA----------------LIFVSHGAGEHSGRY 58 P Q +L QY F + + HG S Y Sbjct: 8 PDQRFSNLD----QYPFSPNYLDDLPGYPGLRAHYLDEGNSDAEDVFLCLHGEPTWSYLY 63 Query: 59 EELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDV-LQHVDSMQKDYPGLPVF 117 ++ + V A D G G+S+ + + D + + + ++ + + Sbjct: 64 RKMIPVFAESGARVIAPDFFGFGKSD-KPV---DEEDYTFEFHRNFLLALIERLDLRNIT 119 Query: 118 LLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLP 172 L+ GG + + P F +++++ ++ +P + F + + Sbjct: 120 LVVQDWGGFLGLTLPMADPSRFKRLIIMNACLMTDPVTQPAFSAFVTQPADGFTA 174 >6AVW-A nrPDB Length = 230 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 12/100 (12%) Query: 197 DPLICRAGLKVCFGIQLLN-AVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAK 255 P G + + + +S+ K P L G+ DR+ + + K Sbjct: 121 YPKTLGGGAVLSGWVPFTSSIISQFPEEAKK--TPILWSHGTDDRMVLFEAGQAALPFLK 178 Query: 256 SQDK--TLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQR 293 K Y G H + N I W+ +R Sbjct: 179 EAGVTCEFKAYPGLGHSIS-------NKELKYIESWIKRR 211 >1HLG-A nrPDB Length = 371 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 61/366 (16%), Positives = 114/366 (31%), Gaps = 88/366 (24%) Query: 10 TPQSIPYQDLPH----LVNADGQYLFCRYWKPTGT-------PKALIFVSHGAGEHSGRY 58 Q I Y P+ +V DG Y+ P G + ++F+ HG + + Sbjct: 8 ISQMITYWGYPNEEYEVVTEDG-YILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNW 66 Query: 59 ------EELARMLMGLDLLVFAHDHVG---------HGQSEGERMVVSDFHVFVR-DVLQ 102 LA +L V+ + G + E S F + D+ Sbjct: 67 ISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFS-FDEMAKYDLPA 125 Query: 103 HVDSMQKDYPGLPVFLLGHSMG---GAIAILTAAERPGHFAGMVLISPLVLAN------- 152 +D + K + +GHS G G IA T ++P+ Sbjct: 126 TIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLIN 185 Query: 153 -----PESATTF-------------------KVLAAKVLNLVLPNLSLGPIDSSVLSRNK 188 P+S F +V + ++LNL+ N + N Sbjct: 186 KLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNT 245 Query: 189 TEVDIY--NSDPLICRAGLKVC-------------FGIQLLNAVSRVERALP-----KLT 228 + +D+Y ++ + +G + N + + P + Sbjct: 246 SRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMN 305 Query: 229 VPFLLLQGSADRLCDSKGAYLLMELAKSQ--DKTLKIYEGAYHVLHKELPEVTNSVFHEI 286 VP + G D L D + LL+ + K + Y + + P+ V+++I Sbjct: 306 VPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEIPFYNHLDFIWAMDAPQ---EVYNDI 362 Query: 287 NMWVSQ 292 +S+ Sbjct: 363 VSMISE 368 >3CN7-A nrPDB Length = 226 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 27/199 (13%), Positives = 60/199 (30%), Gaps = 16/199 (8%) Query: 99 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATT 158 D +++Q P F+L + A+ + P + + + + + Sbjct: 39 DFKPVAEALQMVLPST-RFILPQAPSQAVTVNGGWVMPSWYDILAFSPARAIDEDQLNAS 97 Query: 159 FKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEV--DIYNSDPLICRAGLKVCFGIQLLNA 216 + A + ++ I + S+ V + G+ Sbjct: 98 ADQVIALIDEQRAKGIAAERIILAGFSQGGAVVLHTAFRRY-AQPLGGVLALSTYAPTFD 156 Query: 217 VSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKI--YEGAYHVLHKE 274 ++ ++ P L L GS D + D + ++Q + Y H + E Sbjct: 157 DLALDERHKRI--PVLHLHGSQDDVVDPALGRAAHDALQAQGVEVGWHDYP-MGHEVSLE 213 Query: 275 LPEVTNSVFHEINMWVSQR 293 H+I W+ +R Sbjct: 214 E-------IHDIGAWLRKR 225 >1TAH-B nrPDB Length = 318 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 48/159 (30%), Gaps = 18/159 (11%) Query: 45 IFVSHGAGEH------SGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVR 98 + + HG + + L V+ + G +G +V+ Sbjct: 10 VILVHGLAGTDKFANVVDYWYGIQSDLQSHGAKVYVANLSGFQSDDGPNGRGEQLLAYVK 69 Query: 99 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATT 158 VL + V L+GHS GG + AA P A + I P + Sbjct: 70 QVLAATGAT-------KVNLIGHSQGGLTSRYVAAVAPQLVASVTTIG-----TPHRGSE 117 Query: 159 FKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSD 197 F VL LS I + V +N+D Sbjct: 118 FADFVQDVLKTDPTGLSSTVIAAFVNVFGTLVSSSHNTD 156 >4EB0-A nrPDB Length = 258 Score = 37.1 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 29/180 (16%), Positives = 55/180 (30%), Gaps = 19/180 (10%) Query: 22 LVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHG 81 + G ++ T I +S G + L R L +V + Sbjct: 33 VSGFGGGVIYYP--TGTSLTFGGIAMSPGYTADASSLAWLGRRLASHGFVVLVINTNSRF 90 Query: 82 QSEGERMVVSDFH-VFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFA 140 R ++R +++ + + GHSMGG + A + P Sbjct: 91 DYPDSRASQLSAALNYLR--TSSPSAVRARLDANRLAVAGHSMGGGGTLRIAEQNPS--- 145 Query: 141 GMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLI 200 L + + L + K N +P L +G +V ++ + Y + P Sbjct: 146 ---LKAAVPLTPWHTD--------KTFNTSVPVLIVGAEADTVAPVSQHAIPFYQNLPST 194 >4YCZ-A nrPDB Length = 876 Score = 37.1 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 2 PEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAG 52 PE++SP + PYQ P + +G + W P G L+ HG Sbjct: 325 PEQASPAKGFVKWPYQQRPKIDQQEGPSIPRTNWGPNGL---LVTTHHGEP 372 >2XLB-A nrPDB Length = 320 Score = 36.8 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 43/247 (17%), Positives = 62/247 (25%), Gaps = 24/247 (9%) Query: 31 FCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVV 90 F TG P + HG F G G SE Sbjct: 72 FYAVPDQTG-PHPALVRFHGYNASYDDGIHDIVNWALHGYATFGMLVRGQGGSE------ 124 Query: 91 SDFHVFVRDVLQHVDSMQKDYPGLPVFLL-GHSMGGAIAILTAAERPG-HFAGMVLISPL 148 V + M K + G + A+ P + +I Sbjct: 125 ---DTSVTPGGHALGWMTKGILSKDTYYYRGVYLDAVRALEVIQSFPEVDEHRIGVIGGS 181 Query: 149 VLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNK-TEVDIY---NSDPLICRAG 204 A KV+ P LS V E++ Y NSDP + Sbjct: 182 QGGALAIAAAALSDIPKVVVADYPYLSNFERAVDVALEQPYLEINSYFRRNSDPEVEEKA 241 Query: 205 LKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIY 264 + L+N + P L+ G D++ + DK LK+Y Sbjct: 242 FETLSYFDLINLAGW-------VKQPTLMAIGLIDQVTPPSTVFAAYNH-LETDKELKVY 293 Query: 265 EGAYHVL 271 H Sbjct: 294 RYFGHEF 300 >3I6Y-A nrPDB Length = 280 Score = 36.8 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 41/286 (14%), Positives = 80/286 (27%), Gaps = 70/286 (24%) Query: 16 YQDLPHLVNADGQYL-FCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGL------ 68 ++ H+ N + F Y P + A + V + + E + Sbjct: 17 HKQYSHVSNTLNCAMRFAIYLPPQASTGAKVPVLYWLSGLTCSDENFMQKAGAQRLAAEL 76 Query: 69 DLLVFAHDH--VGHGQSE----------------GERMVVSDFHVFVRDVLQHVDSMQKD 110 + + A D G G ++ + + ++ V + + ++ Sbjct: 77 GIAIVAPDTSPRGEGVADDEGYDLGQGAGFYVNATQAPWNRHYQMYDYVVNELPELIESM 136 Query: 111 YPGL-PVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNL 169 +P + GHSMGG A+ A P + + SP+ Sbjct: 137 FPVSDKRAIAGHSMGGHGALTIALRNPERYQSVSAFSPI--------NNPVNCP------ 182 Query: 170 VLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTV 229 + G + + + K V Sbjct: 183 ------------------------WGQKAFTAYLGKDTDTWREY---DASLLMRAAKQYV 215 Query: 230 PFLLLQGSADRLCDSKGAYLLMELAKSQDK---TLKIYEGAYHVLH 272 P L+ QG AD + ++E A S + L+ +EG H + Sbjct: 216 PALVDQGEADNFLAEQLKPEVLEAAASSNNYPLELRSHEGYDHSYY 261 >5YAL-A nrPDB Length = 342 Score = 36.4 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 33/161 (20%), Positives = 46/161 (28%), Gaps = 22/161 (13%) Query: 36 KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHG--QSEGERMVVSDF 93 +P P+ L+ +S G G L L V A DH + G R+ Sbjct: 86 RPAPVPRPLVVLSPGFGMSRITLTALGEDLASRGYAVAAVDHTYEAPVEFPGGRIEKCTL 145 Query: 94 -HVFVRDVLQHVDSMQKDY----------------PGLPVFLLGHSMGGAIAILTAAERP 136 D V + KD + + GHS+GGA A+ E Sbjct: 146 CDDSRMDPGAVVRNRAKDLRFVLDRLTGPGSELRVDARRIGVAGHSIGGASAVEVMREDR 205 Query: 137 GHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLG 177 A + L P VL +L L Sbjct: 206 RVDAAINLDGNFFTEPPAEGLNKPVL---LLGARRSGLPEP 243 >2JBW-A nrPDB Length = 386 Score = 36.0 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 41/100 (41%), Gaps = 9/100 (9%) Query: 41 PKALIFVSHGAGEHSGRYEELARMLMG-LDLLVFAHDHVGHGQSEGERMVVSDFHVFVR- 98 P + + G E + L+ + D G G+ + + D+ + Sbjct: 151 PHPAVIML-GGLESTKEESFQMENLVLDRGMATATFDGPGQGEMFEYKRIAGDYEKYTSA 209 Query: 99 --DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP 136 D+L +++++ D G +LG S+GG A+ +AA P Sbjct: 210 VVDLLTKLEAIRNDAIG----VLGRSLGGNYALKSAACEP 245 >6IGR-A nrPDB Length = 656 Score = 36.0 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 31/296 (10%), Positives = 74/296 (25%), Gaps = 47/296 (15%) Query: 9 RTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGE--HSGRYEELARMLM 66 R P + G+ + HG + + +++ Sbjct: 394 RFPFPVREPQRVTFETELGEGEGWVLLPEGEQKVPALLNIHGGPHTDYGHGFTHEFQLMA 453 Query: 67 GLDLLVFAHDHVG---HGQSEG----ERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLL 119 V + G +GQ+ R D + + ++++ + ++ Sbjct: 454 ARGYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFDRCLEAVPR-LDAAKTAVM 512 Query: 120 GHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPI 179 G + GG + F + + T+ L + Sbjct: 513 GGAYGGFMTNWITG-HTTRFQAAITDRCISNLISFGGTSDIGL----------RFWDDEL 561 Query: 180 DSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSAD 239 R + +++ PL +K P L++ D Sbjct: 562 GLDFSRRADA-LKLWDLSPLQYVENVK----------------------TPTLIVHSVLD 598 Query: 240 RLCDSKGAYLLMELAKSQDKTLKI--YEGAYHVLHKE-LPEVTNSVFHEINMWVSQ 292 C + A ++ + H L + P+ + +E W+ + Sbjct: 599 HRCPVEQAEQWYAALHKHQVPVRFVRFPEENHELSRSGRPDRRLTRLNEYFAWLER 654 >3AZQ-A nrPDB Length = 662 Score = 35.2 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 223 ALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDK--TLKIYEGAYHVLHKELPEVT 279 ++ VPFLLLQG D +C + +E +EG H ++ V Sbjct: 577 RADRVRVPFLLLQGLEDPVCPPEQCDRFLEAVAGCGVPHAYLSFEGEGHGFRRKETMVR 635 >2O7R-A nrPDB Length = 338 Score = 34.8 bits (78), Expect = 0.043, Method: Composition-based stats. Identities = 51/314 (16%), Positives = 88/314 (28%), Gaps = 46/314 (14%) Query: 2 PEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPK-ALIFVSHGAG------EH 54 P SSP T L L N LF + K L+ HG G Sbjct: 47 PTSSSPVLTK----DLALNPLHN-TFVRLFLPRHALYNSAKLPLVVYFHGGGFILFSAAS 101 Query: 55 SGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGL 114 + ++ M + +++ + D+ + + + Sbjct: 102 TIFHDFCCEMAVHAGVVIASVDYRLAPEHRLPAAYDDAMEALQWIKDSRDEWLTNFADFS 161 Query: 115 PVFLLGHSMGGAIAILTAAERPGHFAGMVL--ISPLVLANPESATTFKVLAAKVLNLVLP 172 F++G S GG IA ++ I LVL P + + + L Sbjct: 162 NCFIMGESAGGNIAYHAGLRAAAVADELLPLKIKGLVLDEPGFGGSKRTGSELRLANDS- 220 Query: 173 NLSLGPIDS-------SVLSRNKTEVD-IYNSDPLICRAGLKVCFGIQLLNAVSRVERAL 224 L +D R+ + S+PL ++ Sbjct: 221 RLPTFVLDLIWELSLPMGADRDHEYCNPTAESEPLYSFDKIRSLGWR------------- 267 Query: 225 PKLTVPFLLLQGSADRLCD--SKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSV 282 +++ D + D + A L + K D + G YH + E PE Sbjct: 268 ------VMVVGCHGDPMIDRQMELAERLEK--KGVDVVAQFDVGGYHAVKLEDPEKAKQF 319 Query: 283 FHEINMWVSQRTAT 296 F + +V T Sbjct: 320 FVILKKFVVDSCTT 333 >5UGZ-A nrPDB Length = 260 Score = 34.8 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 57/199 (28%), Gaps = 23/199 (11%) Query: 95 VFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAI----LTAAERPGHFAGMVLISPLVL 150 V V K Y G + GHS+GG +A + Sbjct: 71 TMVDAVADLYQQFVKHYTGGDYAIFGHSLGGIMAFELVHYILDHGHDMPCALFFSGCRPP 130 Query: 151 ANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFG 210 L + + L P+D + RNK + I+ +K + Sbjct: 131 DRASHEVILHTLPDQAFMEEIVKLGGTPVD---VFRNKELMTIF-------TPIIKNDYR 180 Query: 211 IQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKT-LKIYEGAYH 269 + + LT P +L G AD L LL + KT I+ A H Sbjct: 181 LYEQYVF---QAKARTLTCPIVLFHGDADNLV--MQDELLAWEKFTTRKTRTIIFPAADH 235 Query: 270 VLHKELPEVTNSVFHEINM 288 + + V +N Sbjct: 236 FF---VDKHFEQVVGYVNQ 251 >6ECE-A nrPDB Length = 303 Score = 34.4 bits (77), Expect = 0.057, Method: Composition-based stats. Identities = 33/133 (24%), Positives = 45/133 (33%), Gaps = 13/133 (9%) Query: 36 KPTGTPKALIFVSHGAGEHSGRYEELARMLMGLD--LLVFAHDHVGHGQSEGERMVVSDF 93 P G I + AG Y ELAR L G V A G G++ + Sbjct: 32 NPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGL-GAGETPVYPSF-EEM 89 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANP 153 F D V G V++ GH++GG IA A G+ ++L P Sbjct: 90 VQFCSDSAAGV-------AGDGVYIGGHALGGHIAFYLATMLLDR--GIRPKGLIILDTP 140 Query: 154 ESATTFKVLAAKV 166 V A + Sbjct: 141 PRLGDIPVADADL 153 >1AUO-A nrPDB Length = 218 Score = 34.4 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 29/77 (37%), Gaps = 6/77 (7%) Query: 217 VSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELP 276 +E + + +P L L G D + + E KS+ T+ E + Sbjct: 146 GDELELSASQQRIPALCLHGQYDDVVQNAMGRSAFEHLKSRGVTVTWQE------YPMGH 199 Query: 277 EVTNSVFHEINMWVSQR 293 EV H+I W++ R Sbjct: 200 EVLPQEIHDIGAWLAAR 216 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 83 SEGERMVVSDFHVFVRDVLQHVDSMQKD-YPGLPVFLLGHSMGGAIAILTA 132 S + + + V + V +++ ++ +FL G S GGA+ TA Sbjct: 74 SPARSISLEELEVSAKMVTDLIEAQKRTGIDASRIFLAGFSQGGAVVFHTA 124 >6CL4-A nrPDB Length = 313 Score = 34.4 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 46/158 (29%), Gaps = 28/158 (17%) Query: 74 AHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAA 133 A + G ++ + +L+ V +Q + V L+GHS G AA Sbjct: 55 ALEKAGAKVYIATLSALNSNELRGEQLLEFVRKVQAETGAAKVNLIGHSQGPLACRYVAA 114 Query: 134 ERPG---------------HFAGMVLISPLVLANPESATTFKVLAAKVLNLV------LP 172 P A +V ++ PES A + P Sbjct: 115 THPELIASVTSVNGVNHGSEVADLVRLALTPGRLPESIANA---AMSAFGQLLSALAGSP 171 Query: 173 NLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFG 210 L I++ ++ N P GL +G Sbjct: 172 RLPQSGIEALEALTSEGVAAFNNKYP----QGLPAEWG 205 >1DT3-A nrPDB Length = 269 Score = 34.1 bits (76), Expect = 0.070, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 78 VGH-GQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP 136 GH G + R V + Q V+ +++P V GHS+GGA+A + A+ Sbjct: 108 RGHDGFTSSWRSVADT-------LRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLR 160 Query: 137 GH 138 G+ Sbjct: 161 GN 162 >1OIL-A nrPDB Length = 320 Score = 34.1 bits (76), Expect = 0.078, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 41/137 (29%), Gaps = 18/137 (13%) Query: 45 IFVSHGAGEHSGR------YEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVR 98 I + HG + + L V+ + G +G +V+ Sbjct: 11 IILVHGLTGTDKYAGVLEYWYGIQEDLQQRGATVYVANLSGFQSDDGPNGRGEQLLAYVK 70 Query: 99 DVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATT 158 VL + V L+GHS GG + AA P A + I P + Sbjct: 71 TVLAATGAT-------KVNLVGHSQGGLTSRYVAAVAPDLVASVTTIG-----TPHRGSE 118 Query: 159 FKVLAAKVLNLVLPNLS 175 F VL LS Sbjct: 119 FADFVQGVLAYDPTGLS 135 >3AB1-A nrPDB Length = 360 Score = 34.1 bits (76), Expect = 0.082, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 41/119 (34%), Gaps = 8/119 (6%) Query: 7 PRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE-LARML 65 PR+ P L ++ + G ++ + + G G+ + + L + Sbjct: 134 PRKLP------QLGNIDHLTGSSVYYAVKSVEDFKGKRVVIV-GGGDSALDWTVGLIKNA 186 Query: 66 MGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMG 124 + L+ H+ GHG++ E + V S+++ L L S G Sbjct: 187 ASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHLRSSDG 245 >6BJE-A nrPDB Length = 222 Score = 34.1 bits (76), Expect = 0.087, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 58/156 (37%), Gaps = 13/156 (8%) Query: 81 GQSEGERMVVSDFHVFVRDVLQHVDS-MQKDYPGLPVFLLGHSMGGAIAILTAAERPGHF 139 G S + ++ ++ M+ P + L G S GGA+++ TA P Sbjct: 71 GLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPL 130 Query: 140 AGMVLIS---PLVLANPESATTFKVLAAKV-----LNLVLPNLSLGPIDSSVLSRNKTEV 191 AG+V +S PL A P++A A + L+ ++P + S Sbjct: 131 AGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPAR 190 Query: 192 DIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKL 227 + + P + + ++ +E+ LP + Sbjct: 191 VQFKTYPGVMHSSCP----QEMAAVKEFLEKLLPPV 222 >3HXK-A nrPDB Length = 276 Score = 33.7 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 40/126 (31%), Gaps = 8/126 (6%) Query: 31 FCRYWKPTGTPK---ALIFVSHGAGEHSGRYEE---LARMLMGLDLLVFAHDHVGHGQSE 84 F + P I + G G E LA + V ++ + Sbjct: 29 FYQLQNPRQNENYTFPAIIICPGGGYQHISQRESDPLALAFLAQGYQVLLLNYTVMNKGT 88 Query: 85 GERMVVSDFHVFVRDV-LQHVDSMQKDYPGLPVFLLGHSMGGAIAILTA-AERPGHFAGM 142 + + L H + + VFLLG S GG +A +E+ G+ Sbjct: 89 NYNFLSQNLEEVQAVFSLIHQNHKEWQINPEQVFLLGCSAGGHLAAWYGNSEQIHRPKGV 148 Query: 143 VLISPL 148 +L P+ Sbjct: 149 ILCYPV 154 >6GUD-A nrPDB Length = 292 Score = 33.7 bits (75), Expect = 0.098, Method: Composition-based stats. Identities = 37/174 (21%), Positives = 61/174 (35%), Gaps = 30/174 (17%) Query: 6 SPRRTPQSIPYQDLPHLVNADGQ-YLFCRYW------KPTGT-PKALIFVSHG----AGE 53 S R TP +P + +L N G+ YL W K TG P +I++ G Sbjct: 2 SDRPTPVPLPNSEQFYLENDRGEPYLIQVSWPLHWEDKQTGRGPLPIIYIVDGNALFLTA 61 Query: 54 HSGRYEELAR-MLMGLDLLV----------FAHDHVGHGQSEG---ERMVVSDFHVFVRD 99 + A G ++V + + + VF+ Sbjct: 62 TEAAWRRAAASHFAGGGIIVAIGYPLKGKLYDARRRSFDLTPPTACAPVGYGGADVFLDF 121 Query: 100 VLQHVD-SMQKDYPGLPVF---LLGHSMGGAIAILTAAERPGHFAGMVLISPLV 149 + V ++Q +P + + L GHS GG +A+ RP F + SP + Sbjct: 122 IENSVRPAVQARFPQVSLAREALYGHSYGGLLALHALFTRPQSFDCYIASSPSI 175 >4Q3K-A nrPDB Length = 260 Score = 33.7 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 38/118 (32%), Gaps = 10/118 (8%) Query: 40 TPKALIFVSHGAGE---HSGRYEELARMLMGLDLLVFAHDH--VGHGQSEGERMVVSDFH 94 + + + + G G E +A + F + H + D Sbjct: 52 SKRPAMLIFPGGGYQFCSDREAEPIALSYLAKGYNAFVLRYSVKEHAVFPRPLIDAEDAL 111 Query: 95 VFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN 152 +++D + + ++G S GG +A A E +VL P ++ + Sbjct: 112 SYLKDNAHALHI-----NPDKIAVIGFSAGGHLATTLATEGKVRPNAVVLGYPALIRH 164 >2PPL-A nrPDB Length = 485 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 41/110 (37%), Gaps = 4/110 (3%) Query: 89 VVSDFHVFVRDVLQHVDSM--QKDYPGLPVFLLGHSMGGAIAILTAAERPG--HFAGMVL 144 ++ V V Q +D + + YP V L+GHS+G +A ++ PG G+ Sbjct: 144 AANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGLDP 203 Query: 145 ISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIY 194 + + PE A V + L P ++ +D + Sbjct: 204 VEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFF 253 >5T88-A nrPDB Length = 616 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 30/198 (15%), Positives = 57/198 (28%), Gaps = 21/198 (10%) Query: 23 VNADGQYLFCRYWKPTGTPKALIFVSHGA---GEHSGRYEELARMLMGLDLLVFAHDHVG 79 + DG + K K +G + ++ L + A + G Sbjct: 375 TSKDGTKVHYFIVKGERDEKRAWVFGYGGFNIALTPMFFPQVIPFLKRGGTFIMA-NLRG 433 Query: 80 HGQSEGERMVVSDFHV----FVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAER 135 G GE + D + ++ ++K+ G V G S GG + T +R Sbjct: 434 -GSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKE--GYKVAAWGRSNGGLLVSATLTQR 490 Query: 136 PGHFAGMVLISPLV-LANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIY 194 P ++ P++ + V + N P + + Sbjct: 491 PDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDREFLL---------KYSPYH 541 Query: 195 NSDPLICRAGLKVCFGIQ 212 N DP + G+ Sbjct: 542 NVDPKKKYPPTLIYTGLH 559 >3H2H-A nrPDB Length = 397 Score = 32.9 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 38/107 (35%), Gaps = 9/107 (8%) Query: 55 SGRYEELARMLMGLDLLVFAHDHVGHGQSE-GERMVVSDFHVFVRDVLQ------HVDSM 107 + + L L +V D++G G+S + + + + Sbjct: 103 AKGDDPLVTRLASQGYVVVGSDYLGLGKSNYAYHPYLHSASEASATIDAMRAARSVLQHL 162 Query: 108 QKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAG-MVLISPLVLANP 153 + G V L G+S GG A+ T E H + L++ ++ P Sbjct: 163 KTPLSG-KVMLSGYSQGGHTAMATQREIEAHLSKEFHLVASAPISGP 208 >5LZ5-A nrPDB Length = 388 Score = 32.5 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 15/40 (37%) Query: 39 GTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHV 78 G L+ SHG G Y + L +V A +H Sbjct: 96 GEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHR 135 >5OLJ-A nrPDB Length = 723 Score = 32.5 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 35/115 (30%), Gaps = 9/115 (7%) Query: 43 ALIFVSHGAGEHSGRYEELA----RMLMGLDLLVFAHDHVGHGQSEGE--RMVVSDFHVF 96 ++ V + + + L +V D G G E + VF Sbjct: 505 PVLMVQYSGPNSQQVLDRYSFDWEHYLASKGYVVACVDGRGTGARGEEWRKCTYMQLGVF 564 Query: 97 VRDVLQHVDSMQKDYPGLPVF---LLGHSMGGAIAILTAAERPGHFAGMVLISPL 148 D + P + + G S GG +++ G F + ++P+ Sbjct: 565 ESDDQIAAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVAPV 619 >1EX9-A nrPDB Length = 285 Score = 32.5 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 25/74 (33%) Query: 74 AHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAA 133 A G E + V +LQ V+ + V L+GHS GG AA Sbjct: 34 ALRRDGAQVYVTEVSQLDTSEVRGEQLLQQVEEIVALSGQPKVNLIGHSHGGPTIRYVAA 93 Query: 134 ERPGHFAGMVLISP 147 RP A + Sbjct: 94 VRPDLIASATSVGA 107 >5DWD-A nrPDB Length = 240 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 41/153 (26%), Gaps = 28/153 (18%) Query: 38 TGTPKALIFVSHGAGEHSGRYEELARMLMGL--------------------DLLVFAHDH 77 +G K+L+ + HG G L + F D Sbjct: 37 SGAAKSLVVLLHGYGSDGRDLIALGQFWRDSFPDTMFVAPNAPHVCGGNPFGYEWFPLDL 96 Query: 78 ---VGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAE 134 + G F+ D+ Q L+G S G +A+ T Sbjct: 97 ERDRTLARLAGAETAHPVLDAFLADL-----WAQTGLGPADTILVGFSQGAMMALYTGLR 151 Query: 135 RPGHFAGMVLISPLVLANPESATTFKVLAAKVL 167 P ++ S L++A + +L Sbjct: 152 LPEPLKAIIAFSGLIVAPEKLEAEIASKPPVLL 184 >6GI5-A nrPDB Length = 282 Score = 32.1 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 35/179 (19%), Positives = 55/179 (30%), Gaps = 33/179 (18%) Query: 2 PEESSPRRT--PQSIPYQ----DLPHLVNADGQYLF--CRYWKPTGTPKALIFVSHG--- 50 PE + R Q +PY+ DL + L+ P ++++ G Sbjct: 7 PEATMDRSLLQRQDLPYRFSAVDLDSVDGQRHYRLWLGRPLQAPPAAGYPVVWMLDGNAA 66 Query: 51 -AGEHSGRYEELARM----LMGLDLLV-FAHDHVGH---------GQSEGERMV------ 89 LA L+ + D G GQ++ + Sbjct: 67 VGALDESTLRRLADGDAPLLVAIGYRTPLRIDRAGRTFDYTPASPGQADQRDPLNGLPSG 126 Query: 90 -VSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISP 147 F +RD ++ + Q L GHS GG + + RPG FA SP Sbjct: 127 GADAFLDLLRDGMRPAVAAQAPLDTARQTLWGHSYGGLLVLHALFTRPGEFARYAAASP 185 >1FJ2-A nrPDB Length = 232 Score = 31.8 bits (70), Expect = 0.34, Method: Composition-based stats. Identities = 34/210 (16%), Positives = 68/210 (32%), Gaps = 25/210 (11%) Query: 43 ALIFVSHGAGEHSGRYEELARMLMG---------LDLLVFAHDHVGH--------GQSEG 85 A + HG G+ + E + + + G S Sbjct: 24 AAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRPVTLNMNVAMPSWFDIIGLSPD 83 Query: 86 ERMVVSDFHVFVRDVLQHVDSMQKD-YPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVL 144 + S ++ +D K+ P + L G S GGA+++ TA AG+ Sbjct: 84 SQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTA 143 Query: 145 IS---PLVLANPESA---TTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDP 198 +S PL + P+ + + P + L S + + KT V+ N Sbjct: 144 LSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPL-MFGSLTVEKLKTLVNPANVTF 202 Query: 199 LICRAGLKVCFGIQLLNAVSRVERALPKLT 228 + ++++ +++ LP + Sbjct: 203 KTYEGMMHSSCQQEMMDVKQFIDKLLPPID 232 >4XJV-A nrPDB Length = 271 Score = 31.4 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 10/113 (8%) Query: 28 QYLF-CRYWKPTGTPKALIFVSHGAGE-HSGRYEELARMLMGLDLLVFAHDHVGHGQSEG 85 + +F C Y P T K + F G G H ++ + L L V + G +S Sbjct: 19 ENIFNCLYKNPEATFKLICFPWMGGGSTHFAKWGQDTHDL----LEVHSLRLPGR-ESRV 73 Query: 86 ERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGH 138 E + +D V +V+ + + +D P GHSMG IA TA + Sbjct: 74 EEPLENDISQLVDEVVCALQPVIQD---KPFAFFGHSMGSYIAFRTALGLKEN 123 >1HPL-A nrPDB Length = 449 Score = 31.4 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 49/159 (30%), Gaps = 15/159 (9%) Query: 39 GTPKALIFVSHGA-GEHSGRYEELA--RMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHV 95 T + F+ HG + + M + D ++ + + + Sbjct: 66 NTGRKTRFIIHGFIDKGEESWLSTMCQNMFKVESVNCICVDWKSGSRTAYSQ-ASQNVRI 124 Query: 96 FVRDVLQHVDSMQK--DYPGLPVFLLGHSMGGAIAILTAAERP---GHFAGMVLISPLVL 150 +V V +Q DY V ++GHS+G A G G+ P Sbjct: 125 VGAEVAYLVGVLQSSFDYSPSNVHIIGHSLGSHAAGEAGRRTNGAVGRITGLDPAEPCFQ 184 Query: 151 ANPE------SATTFKVLAAKVLNLVLPNLSLGPIDSSV 183 PE S F + + +PNL G ++ Sbjct: 185 GTPELVRLDPSDAQFVDVIHTDIAPFIPNLGFGMSQTAG 223 >1JFR-A nrPDB Length = 262 Score = 31.4 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 27/86 (31%), Gaps = 12/86 (13%) Query: 2 PEESSPRRTPQSIPYQDLPHLVNAD-----------GQYLFCRYWKPTGTPKALIFVSHG 50 P E P T SI P+ + G ++ GT A++ +S G Sbjct: 4 PYERGPAPTNASIEASRGPYATSQTSVSSLVASGFGGGTIYYPTSTADGTFGAVV-ISPG 62 Query: 51 AGEHSGRYEELARMLMGLDLLVFAHD 76 + L L +VF D Sbjct: 63 FTAYQSSIAWLGPRLASQGFVVFTID 88 >1BU8-A nrPDB Length = 452 Score = 31.4 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 50/157 (31%), Gaps = 9/157 (5%) Query: 46 FVSHGA---GEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQ 102 F+ HG GE + +M + D ++E + + V ++ Sbjct: 74 FIVHGFIDKGEDGWLLDMCKKMFQVEKVNCICVDWRRGSRTEYTQASYNT-RVVGAEIAF 132 Query: 103 HVDSMQKD--YPGLPVFLLGHSMGGAIAILTAAE---RPGHFAGMVLISPLVLANPESAT 157 V + + Y V L+GHS+G + G G+ P PE Sbjct: 133 LVQVLSTEMGYSPENVHLIGHSLGAHVVGEAGRRLEGHVGRITGLDPAEPCFQGLPEEVR 192 Query: 158 TFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIY 194 A V + + + P +S+ +D + Sbjct: 193 LDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFF 229 >2HDW-A nrPDB Length = 367 Score = 30.6 bits (67), Expect = 0.85, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 76/259 (29%), Gaps = 36/259 (13%) Query: 62 ARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVD--SMQKDYPGLPVFLL 119 A+ + + A D G+S G+ V+ + D VD S+ + + ++ Sbjct: 117 AQTMAERGFVTLAFDPSYTGESGGQPRNVASPDINTEDFSAAVDFISLLPEVNRERIGVI 176 Query: 120 GHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNL----- 174 G G +A+ A +V + + S + + L L Sbjct: 177 GICGWGGMALN-AVAVDKRVKAVVTSTMYDMTRVMSKGYNDSVTLEQRTRTLEQLGQQRW 235 Query: 175 ------------SLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVER 222 + D Y + + + +S + Sbjct: 236 KDAESGTPAYQPPYNELKGGEAQFLVDYHDYYMTPRGYHPRAVNSGNAWTMTTPLSFM-- 293 Query: 223 ALPKLT-------VPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHV-LHKE 274 +P LT P LL+ G S+ A ++ K L I GA HV L+ Sbjct: 294 NMPILTYIKEISPRPILLIHGERAH---SRYFSETAYAAAAEPKELLIVPGASHVDLYDR 350 Query: 275 LPEVTNSVFHEINMWVSQR 293 L + F I + + Sbjct: 351 LDRIP---FDRIAGFFDEH 366 >1ODT-C nrPDB Length = 318 Score = 30.6 bits (67), Expect = 0.98, Method: Composition-based stats. Identities = 31/243 (12%), Positives = 58/243 (23%), Gaps = 20/243 (8%) Query: 34 YWKPTGT-PKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSD 92 Y P P I HG F G SE Sbjct: 73 YAVPDKEGPHPAIVKYHGYNASYDGEIHEMVNWALHGYATFGMLVRGQQSSE-------- 124 Query: 93 FHVFVRDVLQHVDSMQKD-YPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLA 151 + + M K + G + A+ + + Sbjct: 125 -DTSISPHGHALGWMTKGILDKDTYYYRGVYLDAVRALEVISSF-DEVDETRIGVTGGAQ 182 Query: 152 NPESATTFKVL--AAKVLNLVLPNLSLGPIDSSVLSRNK-TEVDIYNSDPLICRAGLKVC 208 L K P LS V E++ + ++ Sbjct: 183 GGGLTIAAAALSDIPKAAVADYPYLSNFERAIDVALEEPYLEINSFFRRNGSPETEVQAM 242 Query: 209 FGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAY 268 + + ++ + ++ VP L+ G D++ + +++ K LK+Y Sbjct: 243 KTLSYFDIMNLAD----RVKVPVLMSIGLIDKVTPPSTVFAAYNHLETK-KELKVYRYFG 297 Query: 269 HVL 271 H Sbjct: 298 HEY 300 >3E4D-A nrPDB Length = 278 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 31/147 (21%), Positives = 46/147 (31%), Gaps = 26/147 (17%) Query: 30 LFCRYWKPTG--TPKALIFVSHGAG-EHSGRYE--ELARMLMGLDLLVFAHDH------- 77 F Y P P +++ G H+ E E RM L L+V D Sbjct: 30 TFAVYVPPKAIHEPCPVVWYLSGLTCTHANVMEKGEYRRMASELGLVVVCPDTSPRGNDV 89 Query: 78 ----------VGHG---QSEGERMVVS-DFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSM 123 G G + E + +V + L + + GHSM Sbjct: 90 PDELTNWQMGKGAGFYLDATEEPWSEHYQMYSYVTEELPALIGQHFRADMSRQSIFGHSM 149 Query: 124 GGAIAILTAAERPGHFAGMVLISPLVL 150 GG A+ A + P F +P+V Sbjct: 150 GGHGAMTIALKNPERFKSCSAFAPIVA 176 >4TGL-A nrPDB Length = 269 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 25/50 (50%) Query: 83 SEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTA 132 ++ + + + +++ V K YP V + GHS+GGA A+L A Sbjct: 105 TKVHKGFLDSYGEVQNELVATVLDQFKQYPSYKVAVTGHSLGGATALLCA 154 >4WFK-A nrPDB Length = 273 Score = 30.2 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 33/121 (27%), Gaps = 16/121 (13%) Query: 2 PEESSPRRTPQSIPYQDLPHLVNAD----------GQYLFCRYWKPTGTPKALIFVSHGA 51 P E P T SI P V + G ++ GT A + V+ G Sbjct: 14 PYERGPDPTEDSIEAIRGPFSVATERVSSFASGFGGGTIYYPRETDEGTFGA-VAVAPGF 72 Query: 52 GEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDY 111 G + +VF D G+R + + V+ + Sbjct: 73 TASQGSMSWYGERVASQGFIVFTIDTNTRLDQPGQR-----GRQLLAALDYLVERSDRKV 127 Query: 112 P 112 Sbjct: 128 R 128 >6QPR-A nrPDB Length = 361 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 25/50 (50%) Query: 83 SEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTA 132 ++ + + + +++ V K YP V + GHS+GGA A+L A Sbjct: 197 TKVHKGFLDSYGEVQNELVATVLDQFKQYPSYKVAVTGHSLGGATALLCA 246 >1LGY-A nrPDB Length = 269 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 91 SDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTA 132 S + V D V +P V + GHS+GGA A+L Sbjct: 114 SSYEQVVNDYFPVVQEQLTAHPTYKVIVTGHSLGGAQALLAG 155 >3LWA-A nrPDB Length = 183 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 3/50 (6%) Query: 79 GHGQSEGERMVVSDFHVFVRDVLQ-HVDSMQKDYPGL--PVFLLGHSMGG 125 G+G + G ++ + + RD+ Q V DYP + P F+ S+GG Sbjct: 92 GNGDTPGGTVLGINVRDYSRDIAQDFVTDNGLDYPSIYDPPFMTAASLGG 141 >5UNO-A nrPDB Length = 492 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 9/85 (10%) Query: 73 FAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQ--KDYPGLPVFL-------LGHSM 123 ++ + V H ++E ++ V ++ L HV ++ KD + L LG+S Sbjct: 142 YSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSY 201 Query: 124 GGAIAILTAAERPGHFAGMVLISPL 148 G I A E P M+L + Sbjct: 202 GTRIGSAYAEEFPQRVRAMILDGAV 226 >1KEH-A nrPDB Length = 689 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 47/147 (31%), Gaps = 4/147 (2%) Query: 34 YWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDF 93 YW P + +++G E + ++ +L FA + Q + + Sbjct: 68 YWGPDYEQTTVWLLTNGVPERAQQWYAQQSPDFRANLDAFAAGINAYAQQNPDDISPEVR 127 Query: 94 HVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS----PLV 149 V V + L V G ++G A + +A + L+ Sbjct: 128 QVLPVSGADVVAHAHRLMNFLYVASPGRTLGEGDPPDLADQGANSWAVAPGKTANGNALL 187 Query: 150 LANPESATTFKVLAAKVLNLVLPNLSL 176 L NP + T +LV P+ + Sbjct: 188 LQNPHLSWTTDYFTYYEAHLVTPDFEI 214 >5KRE-A nrPDB Length = 239 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 50/146 (34%), Gaps = 25/146 (17%) Query: 25 ADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSE 84 A G L P G A + HG+G+ + ++ DL F H + + + Sbjct: 6 ASGSVLQRCIVSPAGRHSASLIFLHGSGDSGQGLRMWIKQVLNQDL-TFQHIKIIYPTAP 64 Query: 85 GE---RMVVSDFHVF------VRDVLQHVDSMQKDYPGL---------------PVFLLG 120 M +V+ D +H++S+ L + + G Sbjct: 65 PRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGG 124 Query: 121 HSMGGAIAILTAAERPGHFAGMVLIS 146 SMGG +A+ A AG+ +S Sbjct: 125 FSMGGCMAMHLAYRNHQDVAGVFALS 150 >3O0D-A nrPDB Length = 301 Score = 29.1 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 42/121 (34%), Gaps = 2/121 (1%) Query: 92 DFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERP--GHFAGMVLISPLV 149 ++ + +DS+ + YP + + GHS+GGA A+L GH +V + + Sbjct: 132 SYNNTYNQIGPKLDSVIEQYPDYQIAVTGHSLGGAAALLFGINLKVNGHDPLVVTLGQPI 191 Query: 150 LANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCF 209 + N A L N + +S + R + D +G Sbjct: 192 VGNAGFANWVDKLFFGQENPDVSKVSKDRKLYRITHRGDIVPQVPFWDGYQHCSGEVFID 251 Query: 210 G 210 Sbjct: 252 W 252 >3FCX-A nrPDB Length = 282 Score = 29.1 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 38/104 (36%), Gaps = 21/104 (20%) Query: 66 MGLDLLVFAHDH-----------------VGHG--QSEGERMVVSDFHVFVRDVLQHVDS 106 L+V A D G G E +++ ++ + Sbjct: 72 SEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQL 131 Query: 107 MQKDYPGLPVFL--LGHSMGGAIAILTAAERPGHFAGMVLISPL 148 + ++P P + GHSMGG A++ A + PG + + +P+ Sbjct: 132 INANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPI 175 >3FLA-A nrPDB Length = 267 Score = 28.7 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 34/228 (14%), Positives = 68/228 (29%), Gaps = 24/228 (10%) Query: 42 KALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVL 101 +A + AG + + LA+ L + V A + G E V S + Sbjct: 20 RARLVCLPHAGGSASFFFPLAKALAPA-VEVLAVQYPGRQDRRHEPPVDS--------IG 70 Query: 102 QHVDSMQKDYPGL---PVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATT 158 + + + P+ L GHSMG I A P + A + Sbjct: 71 GLTNRLLEVLRPFGDRPLALFGHSMGAIIGYELALRMPE---------AGLPAPVHLFAS 121 Query: 159 FKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVS 218 + ++ + + S + + + ++ + +DP + L + Sbjct: 122 GRRAPSRYRDDDVRGASDERLVAELRKLGGSDAAML-ADPELLAMVLPA-IRSDYRAVET 179 Query: 219 RVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEG 266 ++ P + G D G E + L++ G Sbjct: 180 YRHEPGRRVDCPVTVFTGDHDPRVSV-GEARAWEEHTTGPADLRVLPG 226 >5DU2-A nrPDB Length = 419 Score = 28.3 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 24/68 (35%), Gaps = 5/68 (7%) Query: 35 WKPTGTPKALIFVSHG--AGEHSGRYEELARMLMGLDLLVFAH--DHVGHGQSEGERMVV 90 W+P ++ +S G +H Y + A G V D VG G V Sbjct: 243 WRPPEDGSPVVLISLGTTFNDHPDFYRQCAEAFAGTPWHVVMALGDRVGAGDLGPLPPNV 302 Query: 91 SDFHVFVR 98 + H +V Sbjct: 303 -EAHRWVS 309 >5W8P-A nrPDB Length = 370 Score = 27.5 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 55/154 (35%), Gaps = 16/154 (10%) Query: 84 EGERMVVSDFHVFVRDVLQH-VDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHF-AG 141 +G+ V VRD + V ++ + ++G SMGGA A+ A P A Sbjct: 112 DGKPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGSMGGARALEWAVMHPDAVRAA 171 Query: 142 MVLISPLVLANPESATTFKVLAAKVLNLV-------------LPNLSLGPIDSSVLSRNK 188 +VL + T +AA + L+L + + R + Sbjct: 172 LVLAVGARATGDQIGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARRIAHLTYRGE 231 Query: 189 TEVDI-YNSDPLICRAGLKVCFGIQLLNAVSRVE 221 E+D + +DP + G + + S +E Sbjct: 232 VELDTRFGNDPQVGPDGPEDPWADGRYAVQSYLE 265 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.118 0.290 Lambda K H 0.267 0.0360 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,556,610 Number of Sequences: 36641 Number of extensions: 335851 Number of successful extensions: 1332 Number of sequences better than 10.0: 140 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 91 Number of HSP's that attempted gapping in prelim test: 1116 Number of HSP's gapped (non-prelim): 213 length of query: 303 length of database: 10,336,785 effective HSP length: 97 effective length of query: 206 effective length of database: 6,782,608 effective search space: 1397217248 effective search space used: 1397217248 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.1 bits)