BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q99538 (433 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4FGU-A nrPDB 870 0.0 4NOM-A nrPDB 765 0.0 4D3Y-A nrPDB 741 0.0 4AWB-A nrPDB 597 e-171 4NOJ-A nrPDB 522 e-148 6AZT-A nrPDB 292 2e-79 5H0I-A nrPDB 291 3e-79 5ZBI-A nrPDB 286 9e-78 5NIJ-A nrPDB 286 2e-77 6DHI-A nrPDB 282 2e-76 5OBT-A nrPDB 242 2e-64 2APO-A nrPDB 36 0.042 5IDF-B nrPDB 34 0.11 4OE4-A nrPDB 31 1.2 2JB2-A nrPDB 30 1.5 5TON-A nrPDB 28 6.3 4QDF-A nrPDB 28 7.0 3II0-A nrPDB 28 7.2 >4FGU-A nrPDB Length = 429 Score = 870 bits (2249), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/416 (99%), Positives = 415/416 (99%) Query: 18 VPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYS 77 +PIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYS Sbjct: 6 IPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYS 65 Query: 78 EDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGP 137 EDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGP Sbjct: 66 EDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGP 125 Query: 138 QDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH 197 QDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH Sbjct: 126 QDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH 185 Query: 198 LPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 257 LPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL Sbjct: 186 LPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 245 Query: 258 VKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKR 317 VKSHTNTSHVMQYG KTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKR Sbjct: 246 VKSHTNTSHVMQYGQKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKR 305 Query: 318 KLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHS 377 KLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHS Sbjct: 306 KLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHS 365 Query: 378 CYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 433 CYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY Sbjct: 366 CYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 421 >4NOM-A nrPDB Length = 441 Score = 765 bits (1976), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/432 (83%), Positives = 395/432 (91%), Gaps = 2/432 (0%) Query: 1 MVWKVAVFLSVALGIGAVPI--DDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR 58 M W+VAV LS+ LG GAVP+ DDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR Sbjct: 1 MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR 60 Query: 59 NGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLR 118 NGIPDEQI+VMMYDDIA SE+NPTPG+VINRPNGTDVY+GV KDYTGEDVTP+NFLAVLR Sbjct: 61 NGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLR 120 Query: 119 GDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKM 178 GDAEAVKG GSGKVLKSGP+DHVFIYFTDHG+TGILVFPN+DLHVKDLN+TI YMY+HKM Sbjct: 121 GDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKM 180 Query: 179 YRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWM 238 Y+KMVFYIEACESGSMMNHLPD+INVYATTAANP+ESSYACYYDE+R TYLGDWYSVNWM Sbjct: 181 YQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWM 240 Query: 239 EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPP 298 EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNK+ISTMKVMQFQGMK +ASSP+ LPP Sbjct: 241 EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPP 300 Query: 299 VTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAA 358 VTHLDLTPSPDVPLTI+KRKL+ TND++ES+ L +IQ+ LDARH+IEKSV KIVSLLA Sbjct: 301 VTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAG 360 Query: 359 SEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPL 418 E+ LSER LT H CY EA+ HFRTHCFNWHS TYE+ALR+LYVL NLCE PYP+ Sbjct: 361 FGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPI 420 Query: 419 HRIKLSMDHVCL 430 RI+++MD VCL Sbjct: 421 DRIEMAMDKVCL 432 >4D3Y-A nrPDB Length = 408 Score = 741 bits (1912), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/408 (84%), Positives = 375/408 (91%) Query: 26 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 85 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQI+VMMYDDIA SEDNPTPGI Sbjct: 1 AGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEDNPTPGI 60 Query: 86 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 145 VINRPNGTDVY GV KDYTGEDVTP+NFLAVLRGDAEAVKG GSGKVL+SGPQDHVF+YF Sbjct: 61 VINRPNGTDVYAGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLRSGPQDHVFVYF 120 Query: 146 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205 T+HG+TG+LVFPNEDLHVKDLN+TI YMY+HKMY+KMVFYIEACESGSMMNHLP++INVY Sbjct: 121 TNHGATGLLVFPNEDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPNDINVY 180 Query: 206 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS 265 ATTAANP ESSYACYYDE+R+TYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS Sbjct: 181 ATTAANPHESSYACYYDEERNTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS 240 Query: 266 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDL 325 HVMQYGNK+ISTMKVMQFQGMK SSP+ LPPVT LDLTPSP+VPLTI+KRKLM+TNDL Sbjct: 241 HVMQYGNKSISTMKVMQFQGMKHSTSSPISLPPVTRLDLTPSPEVPLTILKRKLMSTNDL 300 Query: 326 EESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLH 385 ++S+ L +IQR LDARH+IEKSV KIVSLLA E+LLSERA L H CY EA+ H Sbjct: 301 KQSQNLVGQIQRLLDARHVIEKSVHKIVSLLAGFGETAERLLSERAVLMAHDCYQEAVTH 360 Query: 386 FRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 433 FRTHCFNWHSPTYEYALRHLYVL NLCEKPYP+ RIK++MD VCL HY Sbjct: 361 FRTHCFNWHSPTYEYALRHLYVLANLCEKPYPIDRIKMAMDKVCLSHY 408 >4AWB-A nrPDB Length = 284 Score = 597 bits (1539), Expect = e-171, Method: Compositional matrix adjust. Identities = 283/284 (99%), Positives = 283/284 (99%) Query: 26 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 85 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI Sbjct: 1 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 60 Query: 86 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 145 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF Sbjct: 61 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 120 Query: 146 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY Sbjct: 121 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 180 Query: 206 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS 265 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHT TS Sbjct: 181 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTQTS 240 Query: 266 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPD 309 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPD Sbjct: 241 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPD 284 >4NOJ-A nrPDB Length = 263 Score = 522 bits (1344), Expect = e-148, Method: Compositional matrix adjust. Identities = 243/263 (92%), Positives = 258/263 (98%) Query: 25 DGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPG 84 DGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQI+VMMYDDIA SE+NPTPG Sbjct: 1 DGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPG 60 Query: 85 IVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIY 144 +VINRPNGTDVY+GV KDYTGEDVTP+NFLAVLRGDAEAVKG GSGKVLKSGP+DHVFIY Sbjct: 61 VVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIY 120 Query: 145 FTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINV 204 FTDHG+TGILVFPN+DLHVKDLN+TI YMY+HKMY+KMVFYIEACESGSMMNHLPD+INV Sbjct: 121 FTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINV 180 Query: 205 YATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNT 264 YATTAANP+ESSYACYYDE+R TYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNT Sbjct: 181 YATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNT 240 Query: 265 SHVMQYGNKTISTMKVMQFQGMK 287 SHVMQYGNK+ISTMKVMQFQGMK Sbjct: 241 SHVMQYGNKSISTMKVMQFQGMK 263 >6AZT-A nrPDB Length = 491 Score = 292 bits (748), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 175/437 (40%), Positives = 243/437 (55%), Gaps = 35/437 (8%) Query: 20 IDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSED 79 +D+ G W V+VAGS G+ NYRHQAD CHAYQ++ + G+ DE IVV MYDDIA SE Sbjct: 51 VDEQMTNGTKWAVLVAGSKGYGNYRHQADVCHAYQVLKKGGLKDENIVVFMYDDIAKSEM 110 Query: 80 NPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQD 139 NP PGI+IN P G DVY GVPKDYTG++VT N AVL GD AVKG GSGKV+ S P+D Sbjct: 111 NPRPGIIINSPKGEDVYAGVPKDYTGKNVTVDNLSAVLLGDRSAVKG-GSGKVVDSKPED 169 Query: 140 HVFIYFTDHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH- 197 +F+++++HG G+L PNE L KDL + + + Y++MV Y+EACESGS+ Sbjct: 170 RIFLFYSNHGGPGVLGMPNEPHLVAKDLVDVLKKKHAMGTYKEMVIYLEACESGSIFEGI 229 Query: 198 LPDNINVYATTAANPRESSYACYYDEKRS-------TYLGDWYSVNWMEDSDVEDLTKET 250 LP+++N+YATTA+ +E+SY Y T LGD YSV WMEDS+ +L KE+ Sbjct: 230 LPEDLNIYATTASGAQENSYGTYCPGTEPSPPPEYITCLGDLYSVAWMEDSETHNLKKES 289 Query: 251 LHKQYHLVK---SHTNT----SHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPP----V 299 L +Q++ VK S++NT SHVM+YG+K I KV + G + V LP Sbjct: 290 LEQQFNKVKKRTSNSNTYNTGSHVMEYGSKDIKPEKVYLYLGFD---PATVNLPANQIHF 346 Query: 300 THLDLTPSPDVPLTIMKRKLMNTNDLEESR-QLTEEIQRHLDARHLIEKSVRKIVSLLAA 358 LD D L + ++ ++ E +R ++ EI L R ++ S+ I LL Sbjct: 347 DKLDGVNQRDADLIFLWQRYKKSS--ESTRPEILREITETLTHRGHLDSSIDMIGVLLFG 404 Query: 359 SEAEVEQLLSERAP----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEK 414 + L S RAP + C+ F HC +Y ++H+ N+C Sbjct: 405 PQNGRSTLHSARAPGLPLVDDWECFKSTARLFEKHC----GLLTQYGMKHMRAFANICNS 460 Query: 415 PYPLHRIKLSMDHVCLG 431 +++ C G Sbjct: 461 SVEKSKVEEVFIATCGG 477 >5H0I-A nrPDB Length = 448 Score = 291 bits (745), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 172/428 (40%), Positives = 243/428 (56%), Gaps = 37/428 (8%) Query: 27 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIV 86 G W V++AGS G+ NYRHQA CHAYQI+ R G+ DE IVV MYDDIAY+E NP PG++ Sbjct: 29 GTRWAVLIAGSKGYANYRHQAGVCHAYQILKRGGLKDENIVVFMYDDIAYNESNPRPGVI 88 Query: 87 INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146 IN P+G+DVY GVPKDYTGE+V +NFLA + G+ A+ G GSGKV+ SGP DH+FIY+T Sbjct: 89 INSPHGSDVYAGVPKDYTGEEVNAKNFLAAILGNKSAITG-GSGKVVDSGPNDHIFIYYT 147 Query: 147 DHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNINV 204 DHG+ G++ P++ L+ +LN+ + + Y+ +VFY+EACESGSM LP+++N+ Sbjct: 148 DHGAAGVIGMPSKPYLYADELNDALKKKHASGTYKSLVFYLEACESGSMFEGILPEDLNI 207 Query: 205 YATTAANPRESSYACYYDEKR--------STYLGDWYSVNWMEDSDVEDLTKETLHKQYH 256 YA T+ N ESS+ CYY + + LGD +SV W+EDSDV++ ETL++QYH Sbjct: 208 YALTSTNTTESSW-CYYCPAQENPPPPEYNVCLGDLFSVAWLEDSDVQNSWYETLNQQYH 266 Query: 257 LV-KSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLD---LTPSP---- 308 V K ++ SH QYGN + + + G S+P T LD LTPS Sbjct: 267 HVDKRISHASHATQYGNLKLGEEGLFVYMG-----SNPAN-DNYTSLDGNALTPSSIVVN 320 Query: 309 --DVPLTIMKRKLMNTNDLEESRQLTE-EIQRHLDARHLIEKSVRKIVSLLAASEAEVEQ 365 D L + K + ++ + +I + + R I+ S++ I LL E E Sbjct: 321 QRDADLLHLWEKFRKAPEGSARKEEAQTQIFKAMSHRVHIDSSIKLIGKLLFGIEKCTEI 380 Query: 366 LLSER---APLTGH-SCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRI 421 L + R PL +C + F THC EY +RH + N+C ++ Sbjct: 381 LNAVRPAGQPLVDDWACLRSLVGTFETHC----GSLSEYGMRHTRTIANICNAGISEEQM 436 Query: 422 KLSMDHVC 429 + C Sbjct: 437 AEAASQAC 444 >5ZBI-A nrPDB Length = 532 Score = 286 bits (733), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 169/435 (38%), Positives = 236/435 (54%), Gaps = 47/435 (10%) Query: 27 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIV 86 G W V++AGS G+ NYRHQAD CHAYQI+ + G+ DE I+V MYDDIAY NP PG + Sbjct: 111 GTKWAVLIAGSKGYQNYRHQADVCHAYQILRKGGVKDENIIVFMYDDIAYDIRNPYPGTI 170 Query: 87 INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146 IN P+ DVY+GVPKDYTGEDV QNFLAV+ G+ A+ G GSGKVL + P DH+FIY+T Sbjct: 171 INSPDKKDVYKGVPKDYTGEDVNVQNFLAVILGNKTALTG-GSGKVLDTRPNDHIFIYYT 229 Query: 147 DHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNINV 204 DHG G+L P E L+ DL +T+ + Y +VFY+EACES S+ LPD +N+ Sbjct: 230 DHGYPGVLGMPTEPYLYANDLIDTLKKKHALGTYEGLVFYVEACESASIFEGLLPDGLNI 289 Query: 205 YATTAANPRESSYACYYDEKR-------STYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 257 Y +TAA E S+ Y + T +GD YSV WMEDSDV +L +TLH+QY L Sbjct: 290 YVSTAAKAGEGSWVAYCPSQEPPVPAEYGTCVGDLYSVTWMEDSDVYNLRTQTLHQQYEL 349 Query: 258 VKSHTN-TSHVMQYGNKTISTMKVMQFQGM-----------KRKASSPVPLPPVTHLDLT 305 VK+ S V Q+G+ IS + ++ G + K+SSP H+ Sbjct: 350 VKNKIAYASTVSQFGDFPISKDSLFEYMGTDPANEKRQYEDEEKSSSP-------HVGAV 402 Query: 306 PSPDVPL-----TIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASE 360 + L K + N ++ +QL E+ H R ++ S+ I LL S Sbjct: 403 HQREADLHHFWDKYQKASEGSRNKVDARKQLV-EVMLH---RMHVDDSIESIAKLLFGSG 458 Query: 361 AEVEQLLSERAP-----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKP 415 A+ ++++ P ++ C + F THC + EY +++ L N+C Sbjct: 459 AKASEMMNTIRPPGQPLVSDWDCLKTMVRTFETHCGSLS----EYGMKYTRFLANICNSG 514 Query: 416 YPLHRIKLSMDHVCL 430 ++ + VCL Sbjct: 515 IQKEKMGEASAQVCL 529 >5NIJ-A nrPDB Length = 454 Score = 286 bits (731), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 170/429 (39%), Positives = 237/429 (55%), Gaps = 34/429 (7%) Query: 27 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIV 86 G W V+VAGS+G++NYRHQAD CHAYQ++ + G+ +E IVV MYDDIA + +NP PG + Sbjct: 17 GTRWAVLVAGSSGYWNYRHQADICHAYQLLRKGGLKEENIVVFMYDDIANNYENPRPGTI 76 Query: 87 INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146 IN P+G DVYQGVPKDYTG+DV N AV+ GD AVKG GSGKV+ SGP DH+FI+++ Sbjct: 77 INSPHGKDVYQGVPKDYTGDDVNVDNLFAVILGDKTAVKG-GSGKVVDSGPNDHIFIFYS 135 Query: 147 DHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNINV 204 +HG G+L P L+ DLN+ + + Y+ +VFY+EACESGS+ LP+ +N+ Sbjct: 136 NHGGPGVLGMPTSPYLYANDLNDVLKKKHALGTYKSLVFYLEACESGSIFEGLLPEGLNI 195 Query: 205 YATTAANPRESSYACY-------YDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 257 YATTA+N ESS+ Y + T LGD YSV WMEDS + +L ETLH+QY L Sbjct: 196 YATTASNAEESSWGTYCPGEEPSPPPEYETCLGDLYSVAWMEDSGMHNLQTETLHQQYEL 255 Query: 258 VKSHTN------TSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLD----LTPS 307 VK T SHVMQYG+ IS + + G A+ L +T Sbjct: 256 VKRRTAPVGYSYGSHVMQYGDVGISKDNLDLYMGTN-PANDNFTFADANSLKPPSRVTNQ 314 Query: 308 PDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDA---RHLIEKS---VRKIVSLLAASEA 361 D L K E S + TE ++ L+A R I+ S V KI+ ++ Sbjct: 315 RDADLVHFWEKYRKAP--EGSARKTEAQKQVLEAMSHRLHIDNSVILVGKILFGISRGPE 372 Query: 362 EVEQLLSERAPLTGH-SCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHR 420 + ++ S PL +C + F HC +Y ++H+ N+C + + Sbjct: 373 VLNKVRSAGQPLVDDWNCLKNQVRAFERHC----GSLSQYGIKHMRSFANICNAGIQMEQ 428 Query: 421 IKLSMDHVC 429 ++ + C Sbjct: 429 MEEAASQAC 437 >6DHI-A nrPDB Length = 473 Score = 282 bits (721), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 162/434 (37%), Positives = 235/434 (54%), Gaps = 41/434 (9%) Query: 27 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIV 86 G W V+VAGS G+ NYRHQAD CHAYQI+ + G+ DE I+V MYDDIAY+E NP PG++ Sbjct: 36 GTRWAVLVAGSKGYVNYRHQADVCHAYQILKKGGLKDENIIVFMYDDIAYNESNPHPGVI 95 Query: 87 INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146 IN P G+DVY+GVPKDY GED+ P NF AVL + A+ G GSGKVL SGP DHVFIY+T Sbjct: 96 INHPYGSDVYKGVPKDYVGEDINPPNFYAVLLANKSALTGTGSGKVLDSGPNDHVFIYYT 155 Query: 147 DHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNINV 204 +HG G+L P++ + DLN+ + + Y+ +VFY+E+CESGSM + LP++ N+ Sbjct: 156 NHGGAGVLGMPSKPYIAASDLNDVLKKKHASGTYKSIVFYVESCESGSMFDGLLPEDHNI 215 Query: 205 YATTAANPRESSYACYYDEKRST-------YLGDWYSVNWMEDSDVEDLTKETLHKQYHL 257 Y A++ ESS+ Y + + +GD +SV W+ED DV +L ET +QY + Sbjct: 216 YVMGASDTGESSWVTYCPLQHPSPPPEYDVCVGDLFSVAWLEDCDVHNLQTETFQQQYEV 275 Query: 258 VKSHT------NTSHVMQYGNKTISTMKVMQFQG---------MKRKASSPVPLPPVTHL 302 VK+ T + +HV+QYG+ +S + + G K S P V+ Sbjct: 276 VKNKTIVALIEDGTHVVQYGDVGLSKQTLFVYMGTDPANDNNTFTDKNSLGTPRKAVSQR 335 Query: 303 DLTPSPDVP--LTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASE 360 D D+ +R ++ E+++ E+ H R I+ SV+ I LL E Sbjct: 336 D----ADLIHYWEKYRRAPEGSSRKAEAKKQLREVMAH---RMHIDNSVKHIGKLLFGIE 388 Query: 361 AEVEQLLSERAP----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPY 416 + L + R + C+ + F THC EY ++H+ NLC Sbjct: 389 KGHKMLNNVRPAGLPVVDDWDCFKTLIRTFETHC----GSLSEYGMKHMRSFANLCNAGI 444 Query: 417 PLHRIKLSMDHVCL 430 ++ + C+ Sbjct: 445 RKEQMAEASAQACV 458 >5OBT-A nrPDB Length = 245 Score = 242 bits (618), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 119/228 (52%), Positives = 157/228 (68%), Gaps = 10/228 (4%) Query: 27 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIV 86 G W V+VAGS+G++NYRHQAD CHAYQ++ + G+ +E IVV MYDDIA + +NP PG + Sbjct: 19 GTRWAVLVAGSSGYWNYRHQADICHAYQLLRKGGLKEENIVVFMYDDIANNYENPRPGTI 78 Query: 87 INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146 IN P+G DVYQGVPKDYTG+DV N AV+ GD AVKG GSGKV+ SGP DH+FI+++ Sbjct: 79 INSPHGKDVYQGVPKDYTGDDVNVDNLFAVILGDKTAVKG-GSGKVVDSGPNDHIFIFYS 137 Query: 147 DHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNINV 204 +HG G+L P L+ DLN+ + + Y+ +VFY+EACESGS+ LP+ +N+ Sbjct: 138 NHGGPGVLGMPTSPYLYANDLNDVLKKKHALGTYKSLVFYLEACESGSIFEGLLPEGLNI 197 Query: 205 YATTAANPRESSYACY-------YDEKRSTYLGDWYSVNWMEDSDVED 245 YATTA+N ESS+ Y + T LGD YSV WMEDS + + Sbjct: 198 YATTASNAEESSWGTYCPGEEPSPPPEYETCLGDLYSVAWMEDSGMHN 245 >2APO-A nrPDB Length = 357 Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust. Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%) Query: 181 KMVFYIEACESGSMMNHLPDNINVYATTAA---NPRESSYACYYDEKRSTYLGDWYS--V 235 K V + C+SG+ + L ++I T+A R + C+ +EK + YL D V Sbjct: 186 KDVLFRVKCQSGTYIRKLCEDIGEALGTSAHMQELRRTKSGCF-EEKDAVYLQDLLDAYV 244 Query: 236 NWMEDSDVEDLTKETLHKQYHL 257 W ED D E+L + +Y L Sbjct: 245 FWKEDGDEEELRRVIKPMEYGL 266 >5IDF-B nrPDB Length = 874 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 27/43 (62%) Query: 314 IMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLL 356 + R + N D++E R++ EE+ R + R+LI+ V +I ++L Sbjct: 168 VTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTIL 210 >4OE4-A nrPDB Length = 580 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%) Query: 242 DVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMK-VMQFQGMKRKASSPVPLP 297 D + ET K +HLV N SH + +ST++ +FQG K A+S + LP Sbjct: 309 DYPRIIGETGGKNFHLVHPSANISHAV------LSTIRGTFEFQGQKCSAASRLYLP 359 >2JB2-A nrPDB Length = 489 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 18/113 (15%) Query: 136 GPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACES---- 191 G D ++ F D T +VF E +K+++E + Y +K + A + Sbjct: 236 GGMDRIYYAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTIPPH 295 Query: 192 --GSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSD 242 G + N+LP ++ + A AA P S LG YS W E D Sbjct: 296 LVGRLQNNLPGDV-LTALKAAKPSSSG-----------KLGIEYSRRWWETED 336 >5TON-A nrPDB Length = 414 Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust. Identities = 11/40 (27%), Positives = 22/40 (55%) Query: 178 MYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSY 217 M ++ +EA ++ NH+ D I +++ T NP++ Y Sbjct: 335 MRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEY 374 >4QDF-A nrPDB Length = 390 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 9/49 (18%) Query: 226 STYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSH---TNTSHVMQYG 271 +TY G Y ++W+E SD T ET+ L+ H +N V+QYG Sbjct: 237 ATYFGPSYMIDWLE-SDANGQTIETI-----LINCHYPVSNNEFVLQYG 279 >3II0-A nrPDB Length = 422 Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust. Identities = 11/40 (27%), Positives = 22/40 (55%) Query: 178 MYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSY 217 M ++ +EA ++ NH+ D I +++ T NP++ Y Sbjct: 322 MRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEY 361 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4NOM-A nrPDB 733 0.0 4FGU-A nrPDB 715 0.0 4D3Y-A nrPDB 691 0.0 6DHI-A nrPDB 581 e-166 5NIJ-A nrPDB 581 e-166 6AZT-A nrPDB 574 e-164 5H0I-A nrPDB 567 e-162 5ZBI-A nrPDB 560 e-160 4AWB-A nrPDB 521 e-148 4NOJ-A nrPDB 486 e-138 5OBT-A nrPDB 380 e-106 Sequences not found previously or not previously below threshold: 5W7B-C nrPDB 36 0.027 3CPZ-A nrPDB 34 0.20 2BF1-A nrPDB 33 0.28 5LHE-A nrPDB 32 0.38 1JZT-A nrPDB 32 0.62 4CCZ-A nrPDB 31 0.79 4P1T-A nrPDB 31 0.84 2VRK-A nrPDB 30 1.9 5WLC-LS nrPDB 30 2.0 3ZGA-B nrPDB 28 6.7 CONVERGED! >4NOM-A nrPDB Length = 441 Score = 733 bits (1892), Expect = 0.0, Method: Composition-based stats. Identities = 359/433 (82%), Positives = 395/433 (91%), Gaps = 2/433 (0%) Query: 1 MVWKVAVFLSVALGIGAVPI--DDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR 58 M W+VAV LS+ LG GAVP+ DDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR Sbjct: 1 MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR 60 Query: 59 NGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLR 118 NGIPDEQI+VMMYDDIA SE+NPTPG+VINRPNGTDVY+GV KDYTGEDVTP+NFLAVLR Sbjct: 61 NGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLR 120 Query: 119 GDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKM 178 GDAEAVKG GSGKVLKSGP+DHVFIYFTDHG+TGILVFPN+DLHVKDLN+TI YMY+HKM Sbjct: 121 GDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKM 180 Query: 179 YRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWM 238 Y+KMVFYIEACESGSMMNHLPD+INVYATTAANP+ESSYACYYDE+R TYLGDWYSVNWM Sbjct: 181 YQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWM 240 Query: 239 EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPP 298 EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNK+ISTMKVMQFQGMK +ASSP+ LPP Sbjct: 241 EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPP 300 Query: 299 VTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAA 358 VTHLDLTPSPDVPLTI+KRKL+ TND++ES+ L +IQ+ LDARH+IEKSV KIVSLLA Sbjct: 301 VTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAG 360 Query: 359 SEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPL 418 E+ LSER LT H CY EA+ HFRTHCFNWHS TYE+ALR+LYVL NLCE PYP+ Sbjct: 361 FGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPI 420 Query: 419 HRIKLSMDHVCLG 431 RI+++MD VCL Sbjct: 421 DRIEMAMDKVCLS 433 >4FGU-A nrPDB Length = 429 Score = 715 bits (1846), Expect = 0.0, Method: Composition-based stats. Identities = 414/416 (99%), Positives = 415/416 (99%) Query: 18 VPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYS 77 +PIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYS Sbjct: 6 IPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYS 65 Query: 78 EDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGP 137 EDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGP Sbjct: 66 EDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGP 125 Query: 138 QDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH 197 QDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH Sbjct: 126 QDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH 185 Query: 198 LPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 257 LPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL Sbjct: 186 LPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 245 Query: 258 VKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKR 317 VKSHTNTSHVMQYG KTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKR Sbjct: 246 VKSHTNTSHVMQYGQKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKR 305 Query: 318 KLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHS 377 KLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHS Sbjct: 306 KLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHS 365 Query: 378 CYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 433 CYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY Sbjct: 366 CYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 421 >4D3Y-A nrPDB Length = 408 Score = 691 bits (1782), Expect = 0.0, Method: Composition-based stats. Identities = 346/408 (84%), Positives = 375/408 (91%) Query: 26 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 85 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQI+VMMYDDIA SEDNPTPGI Sbjct: 1 AGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEDNPTPGI 60 Query: 86 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 145 VINRPNGTDVY GV KDYTGEDVTP+NFLAVLRGDAEAVKG GSGKVL+SGPQDHVF+YF Sbjct: 61 VINRPNGTDVYAGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLRSGPQDHVFVYF 120 Query: 146 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205 T+HG+TG+LVFPNEDLHVKDLN+TI YMY+HKMY+KMVFYIEACESGSMMNHLP++INVY Sbjct: 121 TNHGATGLLVFPNEDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPNDINVY 180 Query: 206 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS 265 ATTAANP ESSYACYYDE+R+TYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS Sbjct: 181 ATTAANPHESSYACYYDEERNTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS 240 Query: 266 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDL 325 HVMQYGNK+ISTMKVMQFQGMK SSP+ LPPVT LDLTPSP+VPLTI+KRKLM+TNDL Sbjct: 241 HVMQYGNKSISTMKVMQFQGMKHSTSSPISLPPVTRLDLTPSPEVPLTILKRKLMSTNDL 300 Query: 326 EESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLH 385 ++S+ L +IQR LDARH+IEKSV KIVSLLA E+LLSERA L H CY EA+ H Sbjct: 301 KQSQNLVGQIQRLLDARHVIEKSVHKIVSLLAGFGETAERLLSERAVLMAHDCYQEAVTH 360 Query: 386 FRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 433 FRTHCFNWHSPTYEYALRHLYVL NLCEKPYP+ RIK++MD VCL HY Sbjct: 361 FRTHCFNWHSPTYEYALRHLYVLANLCEKPYPIDRIKMAMDKVCLSHY 408 >6DHI-A nrPDB Length = 473 Score = 581 bits (1497), Expect = e-166, Method: Composition-based stats. Identities = 157/429 (36%), Positives = 228/429 (53%), Gaps = 29/429 (6%) Query: 27 GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIV 86 G W V+VAGS G+ NYRHQAD CHAYQI+ + G+ DE I+V MYDDIAY+E NP PG++ Sbjct: 36 GTRWAVLVAGSKGYVNYRHQADVCHAYQILKKGGLKDENIIVFMYDDIAYNESNPHPGVI 95 Query: 87 INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146 IN P G+DVY+GVPKDY GED+ P NF AVL + A+ G GSGKVL SGP DHVFIY+T Sbjct: 96 INHPYGSDVYKGVPKDYVGEDINPPNFYAVLLANKSALTGTGSGKVLDSGPNDHVFIYYT 155 Query: 147 DHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNINV 204 +HG G+L P++ + DLN+ + + Y+ +VFY+E+CESGSM + LP++ N+ Sbjct: 156 NHGGAGVLGMPSKPYIAASDLNDVLKKKHASGTYKSIVFYVESCESGSMFDGLLPEDHNI 215 Query: 205 YATTAANPRESSYACYY-------DEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHL 257 Y A++ ESS+ Y + +GD +SV W+ED DV +L ET +QY + Sbjct: 216 YVMGASDTGESSWVTYCPLQHPSPPPEYDVCVGDLFSVAWLEDCDVHNLQTETFQQQYEV 275 Query: 258 VKSHT------NTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLD----LTPS 307 VK+ T + +HV+QYG+ +S + + G A+ L Sbjct: 276 VKNKTIVALIEDGTHVVQYGDVGLSKQTLFVYMGT-DPANDNNTFTDKNSLGTPRKAVSQ 334 Query: 308 PDVPLTIMKRKLMNTNDLEESRQLT-EEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQL 366 D L K + + ++++ + R I+ SV+ I LL E + L Sbjct: 335 RDADLIHYWEKYRRAPEGSSRKAEAKKQLREVMAHRMHIDNSVKHIGKLLFGIEKGHKML 394 Query: 367 LSERAP----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIK 422 + R + C+ + F THC EY ++H+ NLC ++ Sbjct: 395 NNVRPAGLPVVDDWDCFKTLIRTFETHC----GSLSEYGMKHMRSFANLCNAGIRKEQMA 450 Query: 423 LSMDHVCLG 431 + C+ Sbjct: 451 EASAQACVS 459 >5NIJ-A nrPDB Length = 454 Score = 581 bits (1497), Expect = e-166, Method: Composition-based stats. Identities = 163/428 (38%), Positives = 229/428 (53%), Gaps = 30/428 (7%) Query: 26 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 85 G W V+VAGS+G++NYRHQAD CHAYQ++ + G+ +E IVV MYDDIA + +NP PG Sbjct: 16 SGTRWAVLVAGSSGYWNYRHQADICHAYQLLRKGGLKEENIVVFMYDDIANNYENPRPGT 75 Query: 86 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 145 +IN P+G DVYQGVPKDYTG+DV N AV+ GD AVKG GSGKV+ SGP DH+FI++ Sbjct: 76 IINSPHGKDVYQGVPKDYTGDDVNVDNLFAVILGDKTAVKG-GSGKVVDSGPNDHIFIFY 134 Query: 146 TDHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNIN 203 ++HG G+L P L+ DLN+ + + Y+ +VFY+EACESGS+ LP+ +N Sbjct: 135 SNHGGPGVLGMPTSPYLYANDLNDVLKKKHALGTYKSLVFYLEACESGSIFEGLLPEGLN 194 Query: 204 VYATTAANPRESSYACYY-------DEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYH 256 +YATTA+N ESS+ Y + T LGD YSV WMEDS + +L ETLH+QY Sbjct: 195 IYATTASNAEESSWGTYCPGEEPSPPPEYETCLGDLYSVAWMEDSGMHNLQTETLHQQYE 254 Query: 257 LVKSHTN------TSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLD----LTP 306 LVK T SHVMQYG+ IS + + G A+ L +T Sbjct: 255 LVKRRTAPVGYSYGSHVMQYGDVGISKDNLDLYMGTN-PANDNFTFADANSLKPPSRVTN 313 Query: 307 SPDVPLTIMKRKLMNTNDLEESRQLTE-EIQRHLDARHLIEKSVRKIVSLLAASEAEVEQ 365 D L K + + + ++ + R I+ SV + +L E Sbjct: 314 QRDADLVHFWEKYRKAPEGSARKTEAQKQVLEAMSHRLHIDNSVILVGKILFGISRGPEV 373 Query: 366 LLSER----APLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRI 421 L R + +C + F HC +Y ++H+ N+C + ++ Sbjct: 374 LNKVRSAGQPLVDDWNCLKNQVRAFERHC----GSLSQYGIKHMRSFANICNAGIQMEQM 429 Query: 422 KLSMDHVC 429 + + C Sbjct: 430 EEAASQAC 437 >6AZT-A nrPDB Length = 491 Score = 574 bits (1480), Expect = e-164, Method: Composition-based stats. Identities = 169/433 (39%), Positives = 237/433 (54%), Gaps = 27/433 (6%) Query: 20 IDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSED 79 +D+ G W V+VAGS G+ NYRHQAD CHAYQ++ + G+ DE IVV MYDDIA SE Sbjct: 51 VDEQMTNGTKWAVLVAGSKGYGNYRHQADVCHAYQVLKKGGLKDENIVVFMYDDIAKSEM 110 Query: 80 NPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQD 139 NP PGI+IN P G DVY GVPKDYTG++VT N AVL GD AVKG GSGKV+ S P+D Sbjct: 111 NPRPGIIINSPKGEDVYAGVPKDYTGKNVTVDNLSAVLLGDRSAVKG-GSGKVVDSKPED 169 Query: 140 HVFIYFTDHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH- 197 +F+++++HG G+L PNE L KDL + + + Y++MV Y+EACESGS+ Sbjct: 170 RIFLFYSNHGGPGVLGMPNEPHLVAKDLVDVLKKKHAMGTYKEMVIYLEACESGSIFEGI 229 Query: 198 LPDNINVYATTAANPRESSYACYY-------DEKRSTYLGDWYSVNWMEDSDVEDLTKET 250 LP+++N+YATTA+ +E+SY Y + T LGD YSV WMEDS+ +L KE+ Sbjct: 230 LPEDLNIYATTASGAQENSYGTYCPGTEPSPPPEYITCLGDLYSVAWMEDSETHNLKKES 289 Query: 251 LHKQYHLVKSHTN-------TSHVMQYGNKTISTMKVMQFQGMKRKA-SSPVPLPPVTHL 302 L +Q++ VK T+ SHVM+YG+K I KV + G + P L Sbjct: 290 LEQQFNKVKKRTSNSNTYNTGSHVMEYGSKDIKPEKVYLYLGFDPATVNLPANQIHFDKL 349 Query: 303 DLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAE 362 D D L + ++ +++ ++ EI L R ++ S+ I LL + Sbjct: 350 DGVNQRDADLIFLWQRYKKSSE-STRPEILREITETLTHRGHLDSSIDMIGVLLFGPQNG 408 Query: 363 VEQLLSERAP----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPL 418 L S RAP + C+ F HC +Y ++H+ N+C Sbjct: 409 RSTLHSARAPGLPLVDDWECFKSTARLFEKHC----GLLTQYGMKHMRAFANICNSSVEK 464 Query: 419 HRIKLSMDHVCLG 431 +++ C G Sbjct: 465 SKVEEVFIATCGG 477 >5H0I-A nrPDB Length = 448 Score = 567 bits (1462), Expect = e-162, Method: Composition-based stats. Identities = 167/436 (38%), Positives = 240/436 (55%), Gaps = 36/436 (8%) Query: 21 DDPEDG-GKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSED 79 D ED G W V++AGS G+ NYRHQA CHAYQI+ R G+ DE IVV MYDDIAY+E Sbjct: 22 DHGEDSVGTRWAVLIAGSKGYANYRHQAGVCHAYQILKRGGLKDENIVVFMYDDIAYNES 81 Query: 80 NPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQD 139 NP PG++IN P+G+DVY GVPKDYTGE+V +NFLA + G+ A+ G GSGKV+ SGP D Sbjct: 82 NPRPGVIINSPHGSDVYAGVPKDYTGEEVNAKNFLAAILGNKSAITG-GSGKVVDSGPND 140 Query: 140 HVFIYFTDHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH- 197 H+FIY+TDHG+ G++ P++ L+ +LN+ + + Y+ +VFY+EACESGSM Sbjct: 141 HIFIYYTDHGAAGVIGMPSKPYLYADELNDALKKKHASGTYKSLVFYLEACESGSMFEGI 200 Query: 198 LPDNINVYATTAANPRESSYACYY-------DEKRSTYLGDWYSVNWMEDSDVEDLTKET 250 LP+++N+YA T+ N ESS+ Y + + LGD +SV W+EDSDV++ ET Sbjct: 201 LPEDLNIYALTSTNTTESSWCYYCPAQENPPPPEYNVCLGDLFSVAWLEDSDVQNSWYET 260 Query: 251 LHKQYHLV-KSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLD------ 303 L++QYH V K ++ SH QYGN + + + G S+P T LD Sbjct: 261 LNQQYHHVDKRISHASHATQYGNLKLGEEGLFVYMG-----SNPAN-DNYTSLDGNALTP 314 Query: 304 ---LTPSPDVPLTIMKRKLMNTNDLEESRQLTE-EIQRHLDARHLIEKSVRKIVSLLAAS 359 + D L + K + ++ + +I + + R I+ S++ I LL Sbjct: 315 SSIVVNQRDADLLHLWEKFRKAPEGSARKEEAQTQIFKAMSHRVHIDSSIKLIGKLLFGI 374 Query: 360 EAEVEQLLSERAP----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKP 415 E E L + R + +C + F THC EY +RH + N+C Sbjct: 375 EKCTEILNAVRPAGQPLVDDWACLRSLVGTFETHC----GSLSEYGMRHTRTIANICNAG 430 Query: 416 YPLHRIKLSMDHVCLG 431 ++ + C Sbjct: 431 ISEEQMAEAASQACAS 446 >5ZBI-A nrPDB Length = 532 Score = 560 bits (1442), Expect = e-160, Method: Composition-based stats. Identities = 165/437 (37%), Positives = 232/437 (53%), Gaps = 39/437 (8%) Query: 21 DDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDN 80 D G W V++AGS G+ NYRHQAD CHAYQI+ + G+ DE I+V MYDDIAY N Sbjct: 105 DVDSKAGTKWAVLIAGSKGYQNYRHQADVCHAYQILRKGGVKDENIIVFMYDDIAYDIRN 164 Query: 81 PTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDH 140 P PG +IN P+ DVY+GVPKDYTGEDV QNFLAV+ G+ A+ G GSGKVL + P DH Sbjct: 165 PYPGTIINSPDKKDVYKGVPKDYTGEDVNVQNFLAVILGNKTALTG-GSGKVLDTRPNDH 223 Query: 141 VFIYFTDHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-L 198 +FIY+TDHG G+L P E L+ DL +T+ + Y +VFY+EACES S+ L Sbjct: 224 IFIYYTDHGYPGVLGMPTEPYLYANDLIDTLKKKHALGTYEGLVFYVEACESASIFEGLL 283 Query: 199 PDNINVYATTAANPRESSYACYYDEKRS-------TYLGDWYSVNWMEDSDVEDLTKETL 251 PD +N+Y +TAA E S+ Y + T +GD YSV WMEDSDV +L +TL Sbjct: 284 PDGLNIYVSTAAKAGEGSWVAYCPSQEPPVPAEYGTCVGDLYSVTWMEDSDVYNLRTQTL 343 Query: 252 HKQYHLVKSHTN-TSHVMQYGNKTISTMKVMQFQGMK-----------RKASSPVPLPPV 299 H+QY LVK+ S V Q+G+ IS + ++ G K+SSP Sbjct: 344 HQQYELVKNKIAYASTVSQFGDFPISKDSLFEYMGTDPANEKRQYEDEEKSSSP------ 397 Query: 300 THLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTE-EIQRHLDARHLIEKSVRKIVSLLAA 358 H+ + L K ++ ++ ++ + R ++ S+ I LL Sbjct: 398 -HVGAVHQREADLHHFWDKYQKASEGSRNKVDARKQLVEVMLHRMHVDDSIESIAKLLFG 456 Query: 359 SEAEVEQLLSERAP-----LTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCE 413 S A+ ++++ P ++ C + F THC EY +++ L N+C Sbjct: 457 SGAKASEMMNTIRPPGQPLVSDWDCLKTMVRTFETHC----GSLSEYGMKYTRFLANICN 512 Query: 414 KPYPLHRIKLSMDHVCL 430 ++ + VCL Sbjct: 513 SGIQKEKMGEASAQVCL 529 >4AWB-A nrPDB Length = 284 Score = 521 bits (1342), Expect = e-148, Method: Composition-based stats. Identities = 283/284 (99%), Positives = 283/284 (99%) Query: 26 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 85 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI Sbjct: 1 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 60 Query: 86 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 145 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF Sbjct: 61 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 120 Query: 146 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY Sbjct: 121 TDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 180 Query: 206 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTS 265 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHT TS Sbjct: 181 ATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTQTS 240 Query: 266 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPD 309 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPD Sbjct: 241 HVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPD 284 >4NOJ-A nrPDB Length = 263 Score = 486 bits (1250), Expect = e-138, Method: Composition-based stats. Identities = 243/263 (92%), Positives = 258/263 (98%) Query: 25 DGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPG 84 DGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQI+VMMYDDIA SE+NPTPG Sbjct: 1 DGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPG 60 Query: 85 IVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIY 144 +VINRPNGTDVY+GV KDYTGEDVTP+NFLAVLRGDAEAVKG GSGKVLKSGP+DHVFIY Sbjct: 61 VVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIY 120 Query: 145 FTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINV 204 FTDHG+TGILVFPN+DLHVKDLN+TI YMY+HKMY+KMVFYIEACESGSMMNHLPD+INV Sbjct: 121 FTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINV 180 Query: 205 YATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNT 264 YATTAANP+ESSYACYYDE+R TYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNT Sbjct: 181 YATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNT 240 Query: 265 SHVMQYGNKTISTMKVMQFQGMK 287 SHVMQYGNK+ISTMKVMQFQGMK Sbjct: 241 SHVMQYGNKSISTMKVMQFQGMK 263 >5OBT-A nrPDB Length = 245 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 119/229 (51%), Positives = 157/229 (68%), Gaps = 10/229 (4%) Query: 26 GGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGI 85 G W V+VAGS+G++NYRHQAD CHAYQ++ + G+ +E IVV MYDDIA + +NP PG Sbjct: 18 SGTRWAVLVAGSSGYWNYRHQADICHAYQLLRKGGLKEENIVVFMYDDIANNYENPRPGT 77 Query: 86 VINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYF 145 +IN P+G DVYQGVPKDYTG+DV N AV+ GD AVKG GSGKV+ SGP DH+FI++ Sbjct: 78 IINSPHGKDVYQGVPKDYTGDDVNVDNLFAVILGDKTAVKG-GSGKVVDSGPNDHIFIFY 136 Query: 146 TDHGSTGILVFPNED-LHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNH-LPDNIN 203 ++HG G+L P L+ DLN+ + + Y+ +VFY+EACESGS+ LP+ +N Sbjct: 137 SNHGGPGVLGMPTSPYLYANDLNDVLKKKHALGTYKSLVFYLEACESGSIFEGLLPEGLN 196 Query: 204 VYATTAANPRESSYACYY-------DEKRSTYLGDWYSVNWMEDSDVED 245 +YATTA+N ESS+ Y + T LGD YSV WMEDS + + Sbjct: 197 IYATTASNAEESSWGTYCPGEEPSPPPEYETCLGDLYSVAWMEDSGMHN 245 >5W7B-C nrPDB Length = 422 Score = 36.2 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 8/98 (8%) Query: 53 YQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQN 112 YQ I +NG + ++ + ++ ++ P IVI G DV G D TP+ Sbjct: 180 YQNISKNGASSRNVKSLI-ESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQ 238 Query: 113 FLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGS 150 A + EA+ L +G HV +Y HG+ Sbjct: 239 LYANVLKMLEALNSH-----LPTG--SHVILYGLAHGA 269 >3CPZ-A nrPDB Length = 362 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 44/137 (32%), Gaps = 12/137 (8%) Query: 185 YIEACES----GSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMED 240 YI C+S G + +++ AC ++ +G+ + ++ Sbjct: 8 YIRGCQSKTYDGKIFPGKGGEKQWICKDTIIHGDTNGACIPPRTQNLCVGELWDKSYGGR 67 Query: 241 SDVEDLTKETLHKQYHLVKSHTNTSHVMQY-----GNKTISTMKVMQFQGMKRKASSPVP 295 S++++ TKE L +K+ + + Y G IS +G P Sbjct: 68 SNIKNDTKELLK---EKIKNAIHKETELLYEYHDTGTAIISKNDKKGQKGKNDPNGLPKG 124 Query: 296 LPPVTHLDLTPSPDVPL 312 ++ L Sbjct: 125 FCHAVQRSFIDYKNMIL 141 >2BF1-A nrPDB Length = 316 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 200 DNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYH--- 256 D IN+ A +P + + +W+ +NW+ED DV + + H++ + Sbjct: 187 DKINLTAPRGGDPEVTFMWTNCRGEFLYCKMNWF-LNWVEDRDVTNQRPKERHRRNYVPC 245 Query: 257 LVKSHTNTSH 266 ++ NT H Sbjct: 246 HIRQIINTWH 255 >5LHE-A nrPDB Length = 207 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 19/85 (22%) Query: 36 GSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVIN--RPNGT 93 GS ++YR A Y I+ G+ E + G I +P G Sbjct: 138 GSGRRHDYRVSAIIAKEYPIVLAGGLTPENV-----------------GEAIRWVKPAGV 180 Query: 94 DVYQGVPKDYTGEDVTPQNFLAVLR 118 DV GV ++ + V + F+AV+R Sbjct: 181 DVSSGVERNGVKDRVLIEAFMAVVR 205 >1JZT-A nrPDB Length = 246 Score = 31.6 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 21/53 (39%) Query: 179 YRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGD 231 Y +VFY + E L +N + + E ++ Y +++ + D Sbjct: 86 YNPVVFYPKRSERTEFYKQLVHQLNFFKVPVLSQDEGNWLEYLKPEKTLCIVD 138 >4CCZ-A nrPDB Length = 644 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 25/77 (32%), Gaps = 5/77 (6%) Query: 357 AASEAEVEQLLSERAPLTGHSCYPEALLH----FRTHCFNWHS-PTYEYALRHLYVLVNL 411 A +LS P + + E LL T+ F+ S +Y L HL +N+ Sbjct: 47 ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNM 106 Query: 412 CEKPYPLHRIKLSMDHV 428 C + Sbjct: 107 CSAGVARKAAEEVTLQT 123 >4P1T-A nrPDB Length = 746 Score = 31.2 bits (69), Expect = 0.84, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 43/137 (31%), Gaps = 12/137 (8%) Query: 185 YIEACES----GSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMED 240 YI C+S G + +++ AC ++ +G+ + ++ Sbjct: 16 YIRGCQSKTYDGKIFPGKGGEKQWICKDTIIHGDTNGACIPPRTQNLCVGELWDKSYGGR 75 Query: 241 SDVEDLTKETLHKQYHLVKSHTNTSHVMQY-----GNKTISTMKVMQFQGMKRKASSPVP 295 S+++ TKE L +K+ + + Y G IS +G P Sbjct: 76 SNIKQDTKELLK---EKIKNAIHKETELLYEYHDTGTAIISKNDKKGQKGKNDPNGLPKG 132 Query: 296 LPPVTHLDLTPSPDVPL 312 ++ L Sbjct: 133 FCHAVQRSFIDYKNMIL 149 >2VRK-A nrPDB Length = 496 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 29/174 (16%), Positives = 57/174 (32%), Gaps = 21/174 (12%) Query: 217 YACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTIS 276 + +YD + T G Y N + D+ V T H+ V+ +++ Q N Sbjct: 299 WGTWYDVEPGTNPGFLYQQNSIRDALVAGATLHIFHRHCDRVR----MANIAQLVNV--- 351 Query: 277 TMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQ 336 V+ +G + + + + + D L + T E +++ Sbjct: 352 LQSVILTEGERMLLTPTYHVFNMFKV----HQDAELLDTWESVERTGPEGELPKVSVSAS 407 Query: 337 RHLDARHLIE---------KSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPE 381 R D + I SV + L + L+ + GH+ + E Sbjct: 408 RAADGKIHISLCNLDFETGASVDIELRGLNGGVSATGTTLTSGR-IDGHNTFDE 460 >5WLC-LS nrPDB Length = 594 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 26/70 (37%), Gaps = 15/70 (21%) Query: 20 IDDPEDGGKHWVVIVAGSNGWYNYRHQ---------------ADACHAYQIIHRNGIPDE 64 + + + H +V++ G+NGW N H D C YQ I R Sbjct: 363 LQNSQTNSVHGIVLLQGNNGWINILHSTSGLWLMGCKIEGVITDFCIDYQPISRGKFRTI 422 Query: 65 QIVVMMYDDI 74 I V Y ++ Sbjct: 423 LIAVNAYGEV 432 >3ZGA-B nrPDB Length = 537 Score = 28.1 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 19/95 (20%) Query: 71 YDDIAYSEDNPTPGIV--INRPNGTDVYQGVPKDYTGEDVTPQNFLAVLR--------GD 120 Y A + P I+ I P+G VY+ VPK T N + + G Sbjct: 327 YATFANNGAKPESHIITKIVDPSGNTVYENVPKTKQIISETVSNEMTSMLLDVINTGTGQ 386 Query: 121 AEAVKG------IGSGKVL---KSGPQDHVFIYFT 146 + AV G GS +V SG +D F+ +T Sbjct: 387 SAAVSGHEMAGKTGSTQVPFDDTSGTKDQWFVGYT 421 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.131 0.367 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,310,881 Number of Sequences: 36641 Number of extensions: 737513 Number of successful extensions: 2025 Number of sequences better than 10.0: 21 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1915 Number of HSP's gapped (non-prelim): 45 length of query: 433 length of database: 10,336,785 effective HSP length: 100 effective length of query: 333 effective length of database: 6,672,685 effective search space: 2222004105 effective search space used: 2222004105 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)