BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96LA8 (375 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5EGS-A nrPDB 765 0.0 5LV5-A nrPDB 677 0.0 1G6Q-1 nrPDB 214 4e-56 5DST-A nrPDB 210 1e-54 3Q7E-A nrPDB 205 2e-53 1F3L-A nrPDB 204 6e-53 6CU3-A nrPDB 203 8e-53 5JMQ-A nrPDB 203 1e-52 4RYL-A nrPDB 200 8e-52 5FUB-A nrPDB 199 1e-51 3R0Q-C nrPDB 197 8e-51 4IKP-A nrPDB 194 4e-50 5IS8-A nrPDB 194 5e-50 3B3J-A nrPDB 194 7e-50 4LWO-B nrPDB 128 4e-30 5EKU-A nrPDB 73 2e-13 4M36-A nrPDB 73 2e-13 6OGN-A nrPDB 60 2e-09 3X0D-A nrPDB 54 8e-08 4G56-A nrPDB 41 8e-04 4QNV-A nrPDB 41 0.001 5FA5-A nrPDB 41 0.001 2AS0-A nrPDB 39 0.003 3EGE-A nrPDB 37 0.012 1XDU-A nrPDB 35 0.039 3D2L-A nrPDB 35 0.053 4PNE-A nrPDB 34 0.097 4KRG-A nrPDB 34 0.13 2R3S-A nrPDB 33 0.15 1WY7-A nrPDB 33 0.19 6GKZ-A nrPDB 33 0.26 3OPN-A nrPDB 33 0.28 3DLC-A nrPDB 32 0.37 4KDR-A nrPDB 32 0.41 3GXO-A nrPDB 32 0.46 1VQ1-A nrPDB 32 0.50 4KDC-A nrPDB 32 0.52 5WP5-A nrPDB 32 0.65 5BP9-A nrPDB 30 1.1 2AVN-A nrPDB 30 1.1 3V8V-A nrPDB 30 1.3 3CCF-A nrPDB 30 1.6 4P7C-A nrPDB 30 1.6 4QPN-A nrPDB 30 1.6 5I2H-A nrPDB 30 1.6 5Z9O-A nrPDB 30 2.2 4X3Q-A nrPDB 30 2.5 3LEC-A nrPDB 29 2.6 5Y27-B nrPDB 29 2.8 3DMF-A nrPDB 29 3.2 4LEC-A nrPDB 29 3.4 6QDV-c nrPDB 29 3.5 2PJD-A nrPDB 29 3.5 3R9X-B nrPDB 29 3.6 1R74-A nrPDB 29 3.6 3CJR-A nrPDB 29 3.7 4HJW-A nrPDB 29 4.0 3HP7-A nrPDB 29 4.1 1D2C-A nrPDB 29 4.3 3BUS-A nrPDB 28 6.9 5JE5-A nrPDB 28 7.8 3BKX-A nrPDB 28 8.2 4QDJ-A nrPDB 27 10.0 >5EGS-A nrPDB Length = 376 Score = 765 bits (1975), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/375 (99%), Positives = 374/375 (99%) Query: 1 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM 60 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM Sbjct: 2 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM 61 Query: 61 IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA 120 IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA Sbjct: 62 IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA 121 Query: 121 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE 180 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE Sbjct: 122 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE 181 Query: 181 GGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG 240 GGLLLPASAELFI PISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG Sbjct: 182 GGLLLPASAELFIVPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG 241 Query: 241 LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE 300 LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE Sbjct: 242 LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE 301 Query: 301 SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK 360 SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK Sbjct: 302 SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK 361 Query: 361 VGDQEEKTKDFAMED 375 VGDQEEKTKDFAMED Sbjct: 362 VGDQEEKTKDFAMED 376 >5LV5-A nrPDB Length = 403 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/378 (88%), Positives = 349/378 (92%), Gaps = 3/378 (0%) Query: 1 MSQPKKRKLESGGGGEGGEGTEEEDGAEREA---ALERPRRTKRERDQLYYECYSDVSVH 57 MS KKRKLESG G G G E + A RPRRTK ERDQLYYECYSDVSVH Sbjct: 26 MSLSKKRKLESGDSGGAGAGGEGAEEENGGEQEAAPPRPRRTKSERDQLYYECYSDVSVH 85 Query: 58 EEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW 117 EEMIAD+VRT+AYRLGIL+NWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW Sbjct: 86 EEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW 145 Query: 118 QQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKW 177 QQAREVVR NGLEDRVHVLPGPVETVELPE+VDAIVSEWMGYGLLHESMLSSVLHARTKW Sbjct: 146 QQAREVVRLNGLEDRVHVLPGPVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKW 205 Query: 178 LKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIV 237 LKEGGLLLPASAELF+APISDQMLEWRLGFWSQVKQHYGVDMSC+E FATRCLMGHSEIV Sbjct: 206 LKEGGLLLPASAELFVAPISDQMLEWRLGFWSQVKQHYGVDMSCMESFATRCLMGHSEIV 265 Query: 238 VQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFP 297 VQ LSGEDVLARPQRFAQLEL+RAGLEQELEAGVGGRFRCSCYGSAP+HGFA+WFQVTFP Sbjct: 266 VQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFP 325 Query: 298 GGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLL 357 GG+SEKPLVLSTSP HPATHWKQALLYLNEPV VEQDTD+SGEITLLPS DNPRRLR+LL Sbjct: 326 GGDSEKPLVLSTSPLHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILL 385 Query: 358 RYKVGDQEEKTKDFAMED 375 RYKVGD EEKTKDFAMED Sbjct: 386 RYKVGDHEEKTKDFAMED 403 >1G6Q-1 nrPDB Length = 328 Score = 214 bits (546), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 112/316 (35%), Positives = 172/316 (54%), Gaps = 14/316 (4%) Query: 47 YYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR 106 Y++ Y +HEEM+ D VRT +YR I++N + K VLDVG GTGILS+F A+ GA+ Sbjct: 3 YFDSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAK 62 Query: 107 RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMGYGLLHES 165 V V+ S+I + A+E+V NG D++ +L G +E V LP +VD I+SEWMGY LL+ES Sbjct: 63 HVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLYES 122 Query: 166 MLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGVDMSCLEG 224 M+ +VL+AR +L EGGL+ P + +A + D Q + +L +W V YG D S Sbjct: 123 MMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDV---YGFDYS---P 176 Query: 225 FATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAP 284 F L E +V + +V + + +L+ + + F+ + Sbjct: 177 FVPLVL---HEPIVDTVERNNVNTTSDKLIEFDLNTVKIS---DLAFKSNFKLTAKRQDM 230 Query: 285 MHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLL 344 ++G WF + FP + ++P+ ST P P THWKQ + Y + + E + GE+ Sbjct: 231 INGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCS 290 Query: 345 PSRDNPRRLRVLLRYK 360 P+ N R L + + YK Sbjct: 291 PNEKNNRDLNIKISYK 306 >5DST-A nrPDB Length = 332 Score = 210 bits (534), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 110/309 (35%), Positives = 175/309 (56%), Gaps = 16/309 (5%) Query: 47 YYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR 106 Y++ Y+ +HEEM+ D VRT YR + N + K VLDVG+GTGILS+F A+AGA+ Sbjct: 14 YFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAK 73 Query: 107 RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMGYGLLHES 165 +V+ +E S+I + ++++ N L++ + + G VE VELP E+VD I+SEWMGY L +ES Sbjct: 74 KVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYES 133 Query: 166 MLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGVDMSCLEG 224 ML++V+ AR KWLK GGL+ P A L++ I D Q ++++ +W V YG DM+C+ Sbjct: 134 MLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENV---YGFDMTCIRD 190 Query: 225 FATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAP 284 A + E +V + + V+ ++++ E E F + Sbjct: 191 VAMK------EPLVDIVDPKQVVTNACLIKEVDIYTVKTE---ELSFTSAFCLQIQRNDY 241 Query: 285 MHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLL 344 +H +F + F + K + ST+P P THWKQ + YL + + V + ++ G I++ Sbjct: 242 VHALVTYFNIEFT--KCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMK 299 Query: 345 PSRDNPRRL 353 P+ N R L Sbjct: 300 PNAKNVRDL 308 >3Q7E-A nrPDB Length = 349 Score = 205 bits (522), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 113/322 (35%), Positives = 174/322 (54%), Gaps = 16/322 (4%) Query: 34 ERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGT 93 E+P Y++ Y+ +HEE++ D VRT YR + N + K VLDVG+GT Sbjct: 18 EKPNAEDMTSKDYYFDSYAHFGIHEELLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 77 Query: 94 GILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAI 152 GIL +F A+AGAR+V +E S+I A ++V+ N L+ V ++ G VE VELP E+VD I Sbjct: 78 GILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDII 137 Query: 153 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQV 211 +SEWMGY L +ESML++VLHAR KWL GL+ P A L++ I D Q ++++ +W V Sbjct: 138 ISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV 197 Query: 212 KQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGV 271 YG DMSC++ A + E +V + + ++ ++++ +E + Sbjct: 198 ---YGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVKVE---DLTF 245 Query: 272 GGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQV 331 F + +H +F + F K STSP P THWKQ + Y+ + + V Sbjct: 246 TSPFCLQVKRNDYVHALVAYFNIEFT--RCHKRTGFSTSPESPYTHWKQTVFYMEDYLTV 303 Query: 332 EQDTDVSGEITLLPSRDNPRRL 353 + ++ G I + P+ N R L Sbjct: 304 KTGEEIFGTIGMRPNAKNNRDL 325 >1F3L-A nrPDB Length = 321 Score = 204 bits (518), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 117/327 (35%), Positives = 180/327 (55%), Gaps = 15/327 (4%) Query: 40 KRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIF 99 + + D +Y+ Y +HEEM+ D+VRT++YR I +N + K VLDVG GTGILS+F Sbjct: 3 QEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMF 62 Query: 100 CAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMG 158 A+AGA++V AV+ S I QA +++R N LED + ++ G +E V LP E+VD I+SEWMG Sbjct: 63 AAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMG 122 Query: 159 YGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW-RLGFWSQVKQHYGV 217 Y LL ESML SVL+A++K+L +GG + P + + +SD R+ FW V YG Sbjct: 123 YFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDV---YGF 179 Query: 218 DMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRC 277 +MSC++ E VV+ + + +++ P ++ + +LE R Sbjct: 180 NMSCMKKAVI------PEAVVEVVDHKTLISDPCDIKHIDCHTTSI-SDLEFSSDFTLRT 232 Query: 278 SCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDV 337 + +A A +F + F + +V ST P THWKQ + L +P V+ + Sbjct: 233 T--KTAMCTAVAGYFDIYFEKNCHNR-VVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEAL 289 Query: 338 SGEITLLPSRDNPRRLRVLLRYKVGDQ 364 G+IT+ ++ +PR L V L Q Sbjct: 290 KGKITVHKNKKDPRSLIVTLTLNSSTQ 316 >6CU3-A nrPDB Length = 336 Score = 203 bits (517), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 112/323 (34%), Positives = 177/323 (54%), Gaps = 17/323 (5%) Query: 56 VHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA 115 +HEEM+ D +RT+AY+ IL+N + K VLD+G GTGIL +F A+AGA+RV ++ S Sbjct: 25 IHEEMLKDGIRTNAYKNAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAKRVIGIDMSD 84 Query: 116 IWQQAREVVRFNGLEDRVHVLPGPVETV-ELP---EQVDAIVSEWMGYGLLHESMLSSVL 171 I +AR++V NG + ++ G VE + +LP E+VD I+SEWMGY LL+ESML +VL Sbjct: 85 IIDKARQIVSDNGYSHVIELIKGKVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQTVL 144 Query: 172 HARTKWLKEGGLLLPASAELFIAPISDQMLEW-RLGFWSQVKQHYGVDMSCLEGFATRCL 230 AR +WL+ GG L P ++I I D + ++ FW V YG + S ++ A R Sbjct: 145 SARDRWLRPGGYLFPDKCTMYICGIEDSEYKRDKIDFWDNV---YGFNFSAIKADALR-- 199 Query: 231 MGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAI 290 E +V + + ++ +F +++L+ ++ E + F + F Sbjct: 200 ----EPLVDFVESQQIITTQSKFLEIDLNT--IQPEDLKQITTSFEFTSQYQEYCQAFVA 253 Query: 291 WFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNP 350 WF F G KP+ ST PF THWKQ + YL + ++ + + G IT+ ++ N Sbjct: 254 WFDCVFSRG-PHKPVEFSTGPFTEGTHWKQTVFYLENDLPLKPNDVIKGTITISQNKSNH 312 Query: 351 RRLRVLLRYKVGDQEEKTKDFAM 373 R L + ++Y V ++D+ M Sbjct: 313 RDLDISMKYTVNGGAVISQDYIM 335 >5JMQ-A nrPDB Length = 446 Score = 203 bits (516), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 126/332 (37%), Positives = 180/332 (54%), Gaps = 15/332 (4%) Query: 43 RDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQ 102 +D+ Y++ Y + +H EM+AD+ RT Y IL+N +L+ K +LDVG GTGI+S+FCA Sbjct: 111 QDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAH 170 Query: 103 -AGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGL 161 A + VYAVEAS + Q ++V NG D + V VE V LPE+VD +VSEWMG L Sbjct: 171 HARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVVLPEKVDVLVSEWMGTCL 230 Query: 162 LHESMLSSVLHARTKWLKEGGLLLPASAELFIAPIS-DQMLEWRLGFWSQVKQHYGVDMS 220 L E M+ S+L+AR WLK G++ P +A L + P S ++ ++ FW Y ++S Sbjct: 231 LFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLFWDNA---YEFNLS 287 Query: 221 CLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCY 280 L+ A + + L ED L+ P QL++ R +LE + G R Sbjct: 288 ALKSLAIKEFFSRPK-SNHILKPEDCLSEPCTILQLDM-RTVQVPDLET-MRGELRFDIQ 344 Query: 281 GSAPMHGFAIWFQVTFPGGESEKP-LVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSG 339 + +HGF WF V F E +P VLST P HP THWKQ L +++PV V V+G Sbjct: 345 KAGTLHGFTAWFSVYFQSLEEGQPQQVLSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVTG 404 Query: 340 EITLLPSRDNP---RRLRVLLRYKVGDQEEKT 368 + L + NP R + V L + V + T Sbjct: 405 SVVL---QRNPVWRRHMSVSLSWVVTSALDPT 433 >4RYL-A nrPDB Length = 340 Score = 200 bits (509), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 113/326 (34%), Positives = 176/326 (53%), Gaps = 17/326 (5%) Query: 35 RPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTG 94 R + + D +Y+ Y +HEEM+ D++RT++YR I +N + K VLDVG GTG Sbjct: 17 RGSDLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTG 76 Query: 95 ILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIV 153 ILS+F A+AGA++V V+ S I QA +++R N LED + ++ G +E V LP E+VD I+ Sbjct: 77 ILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVII 136 Query: 154 SEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVK 212 SEWMGY LL ESML SVL+A+ K+L +GG + P + + +SD R+ FW V Sbjct: 137 SEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDV- 195 Query: 213 QHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGL-EQELEAGV 271 YG MSC++ E VV+ L + +++ P ++ + + E + Sbjct: 196 --YGFKMSCMKKAVI------PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDF 247 Query: 272 GGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQV 331 + + +A F I+F+ +V ST P THWKQ + L +P V Sbjct: 248 TLKITRTSMCTAIAGYFDIYFE-----KNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSV 302 Query: 332 EQDTDVSGEITLLPSRDNPRRLRVLL 357 + + G++T+ ++ +PR L V L Sbjct: 303 KAGEALKGKVTVHKNKKDPRSLTVTL 328 >5FUB-A nrPDB Length = 337 Score = 199 bits (507), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 131/342 (38%), Positives = 186/342 (54%), Gaps = 22/342 (6%) Query: 43 RDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQ 102 +D Y+ Y + +H EM++D+ RT+ YR IL N AALR K VLD+G GTG++S+FCA Sbjct: 5 QDDEYFGNYGTLRLHLEMLSDKPRTETYRQVILSNSAALREKVVLDLGCGTGVISLFCAL 64 Query: 103 -AGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGL 161 A VYAVEAS++ + E+V+ NG + V V E + LP +VD +VSEWMG L Sbjct: 65 LAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENLTLPTKVDVLVSEWMGNCL 124 Query: 162 LHESMLSSVLHARTKWLKEGGLLLPASAELFIAP---ISDQMLEWRLGFWSQVKQHYGVD 218 L E ML SVL AR +WLK+GG++ P+SA L I P SD ++ FW + YG++ Sbjct: 125 LFEYMLESVLLARDRWLKKGGMMWPSSACLTIVPCQAFSD--YRQKVEFW---ENPYGLN 179 Query: 219 MSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCS 278 S L+ A + + + L ED L+ P L++ + +LE + G F + Sbjct: 180 FSYLQSLAQKEFLSKPKF-SHHLQPEDCLSTPADVITLDMVTIQV-SDLER-LKGEFTFT 236 Query: 279 CYGSAPMHGFAIWFQVTFPGGESEKPLV-LSTSPFHPATHWKQALLYLNEPVQVEQDTDV 337 S HGF +WF F E + P + L+T P+ THWKQ L L+ PV VE+ + Sbjct: 237 VEKSGMFHGFTVWFSAHFQCLEEDGPSIELNTGPYSEITHWKQTLFMLDAPVSVEEGDII 296 Query: 338 SGEITLLPSRDNP---RRLRVLLRYKVGDQE---EKTKDFAM 373 +G I L + NP R L + + + E KTK F M Sbjct: 297 AGSIRL---QRNPIWRRHLSITFLWNINSTEVSTVKTKCFPM 335 >3R0Q-C nrPDB Length = 376 Score = 197 bits (500), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 118/342 (34%), Positives = 190/342 (55%), Gaps = 25/342 (7%) Query: 41 RERDQLYYEC-YSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIF 99 +E D Y C YS + ++M++DRVR DAY + +N GKTVLDVG G+GIL+I+ Sbjct: 21 KEVDYAQYFCTYSFLYHQKDMLSDRVRMDAYFNAVFQNKHHFEGKTVLDVGTGSGILAIW 80 Query: 100 CAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGY 159 AQAGAR+VYAVEA+ + AR +V+ N L+ V V+ G VE + LPE+VD I+SEWMGY Sbjct: 81 SAQAGARKVYAVEATKMADHARALVKANNLDHIVEVIEGSVEDISLPEKVDVIISEWMGY 140 Query: 160 GLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQ------------MLEWRLGF 207 LL ESM SV+ AR +WLK G++ P+ A +++API M +W F Sbjct: 141 FLLRESMFDSVISARDRWLKPTGVMYPSHARMWLAPIKSNIADRKRNDFDGAMADWH-NF 199 Query: 208 WSQVKQHYGVDMSCL-EGFATRCLMGHSEIVV-QGLSGEDVLARPQRFAQLELSRAGLE- 264 ++K +YGVDM L + FA + + + L+ + ++ P +++ A + Sbjct: 200 SDEIKSYYGVDMGVLTKPFAEEQEKYYIQTAMWNDLNPQQIIGTPTIVKEMDCLTASVSE 259 Query: 265 -QELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE---SEKPLVLSTSPF-HPATHWK 319 +E+ + V + GF WF V F G + +++ + L+T+P THW Sbjct: 260 IEEVRSNVTSVINME---HTRLCGFGGWFDVQFSGRKEDPAQQEIELTTAPSEQHCTHWG 316 Query: 320 QALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKV 361 Q + ++ P+ VE+ +++ + + S++N R + + L ++ Sbjct: 317 QQVFIMSNPINVEEGDNLNLGLLMSRSKENHRLMEIELNCEI 358 >4IKP-A nrPDB Length = 341 Score = 194 bits (494), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 121/315 (38%), Positives = 169/315 (53%), Gaps = 15/315 (4%) Query: 38 RTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILS 97 RT+ Y++ Y +S + M+ D VRT Y+ IL+N + K VLDVG G+GILS Sbjct: 1 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS 60 Query: 98 IFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWM 157 F AQAGAR++YAVEAS + Q A +V+ N L DR+ V+PG VE V LPEQVD I+SE M Sbjct: 61 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPM 120 Query: 158 GYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQ 213 GY L +E ML S LHA+ K+LK G + P ++ +AP +D+ L + FW Q Sbjct: 121 GYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSF 179 Query: 214 HYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLEL-SRAGLEQELEAGVG 272 H GVD+S L G A + VV ++A+ ++ L ++ G +E Sbjct: 180 H-GVDLSALRGAAVDEYF--RQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIP-- 234 Query: 273 GRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVE 332 F+ S +HG A WF V F G S + LST+P P THW Q P+ + Sbjct: 235 --FKFHMLHSGLVHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAK 290 Query: 333 QDTDVSGEITLLPSR 347 +SG L+ ++ Sbjct: 291 AGDTLSGTCLLIANK 305 >5IS8-A nrPDB Length = 381 Score = 194 bits (493), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 121/315 (38%), Positives = 169/315 (53%), Gaps = 15/315 (4%) Query: 38 RTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILS 97 RT+ Y++ Y +S + M+ D VRT Y+ IL+N + K VLDVG G+GILS Sbjct: 15 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS 74 Query: 98 IFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWM 157 F AQAGAR++YAVEAS + Q A +V+ N L DR+ V+PG VE V LPEQVD I+SE M Sbjct: 75 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPM 134 Query: 158 GYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQ 213 GY L +E ML S LHA+ K+LK G + P ++ +AP +D+ L + FW Q Sbjct: 135 GYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSF 193 Query: 214 HYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLEL-SRAGLEQELEAGVG 272 H GVD+S L G A + VV ++A+ ++ L ++ G +E Sbjct: 194 H-GVDLSALRGAAVDEYF--RQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIP-- 248 Query: 273 GRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVE 332 F+ S +HG A WF V F G S + LST+P P THW Q P+ + Sbjct: 249 --FKFHMLHSGLVHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAK 304 Query: 333 QDTDVSGEITLLPSR 347 +SG L+ ++ Sbjct: 305 AGDTLSGTCLLIANK 319 >3B3J-A nrPDB Length = 480 Score = 194 bits (492), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 125/327 (38%), Positives = 173/327 (52%), Gaps = 18/327 (5%) Query: 29 REAALERP---RRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKT 85 R LER RT+ Y++ Y +S + M+ D VRT Y+ IL+N + K Sbjct: 102 RGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKI 161 Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVEL 145 VLDVG G+GILS F AQAGAR++YAVEAS + Q A +V+ N L DR+ V+PG VE V L Sbjct: 162 VLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSL 221 Query: 146 PEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW-- 203 PEQVD I+SE MGY L +E ML S LHA+ K+LK G + P ++ +AP +D+ L Sbjct: 222 PEQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQ 280 Query: 204 --RLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLEL-SR 260 + FW Q H GVD+S L G A + VV ++A+ ++ L ++ Sbjct: 281 FTKANFWYQPSFH-GVDLSALRGAAVDEYF--RQPVVDTFDIRILMAKSVKYTVNFLEAK 337 Query: 261 AGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQ 320 G +E F+ S +HG A WF V F G S + LST+P P THW Q Sbjct: 338 EGDLHRIEIP----FKFHMLHSGLVHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQ 391 Query: 321 ALLYLNEPVQVEQDTDVSGEITLLPSR 347 P+ + +SG L+ ++ Sbjct: 392 VRCLFQSPLFAKAGDTLSGTCLLIANK 418 >4LWO-B nrPDB Length = 368 Score = 128 bits (321), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 105/325 (32%), Positives = 158/325 (48%), Gaps = 64/325 (19%) Query: 47 YYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR 106 YYE YSD++VH M+ D R YR I ++ A++ GK V+DVG+GTGILS++ A+AGA+ Sbjct: 20 YYESYSDLAVHRLMLEDAQRMSFYRKSIEQS-ASIEGKVVVDVGSGTGILSMWAARAGAK 78 Query: 107 RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETV--------------ELPE-QVDA 151 V+++EAS++ + VV N L ++ VL VE + +L + V Sbjct: 79 HVFSIEASSLSEFQIGVVEDNDLSTKITVLGDTVENIIAGGVANFVNRHKAKLGKCGVAV 138 Query: 152 IVSEWMGYGLLHESMLSSVLHARTKWLKEGGLL--------LPASAELFIAPISDQ--ML 201 ++SEWMG+ L HE ML SV+ AR + L +P A +F+API+ + + Sbjct: 139 LLSEWMGFYLFHEGMLPSVIRARNFFQDVNAALGVLQPIEMIPERATVFVAPITCKPYYV 198 Query: 202 EWRLGFWSQVKQHYGVDMS----------------CLEGFATRCLMGHSEIVVQ-GLSG- 243 + FW V G+D S +E CL+ +++ LS Sbjct: 199 QRYKNFWRDVD---GLDFSRYGRIEYEVYLEQASPLVECLPPLCLLHEGLSLIELNLSTV 255 Query: 244 -EDVLARPQRFAQLELSRAGLEQEL--EAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE 300 E+VL +L + Q+ EAG GR + GF +WF V++ G Sbjct: 256 QEEVLTSLHNTVHFDLKESAEFQQHAREAGSEGR--------VSVDGFTVWFDVSY-GAH 306 Query: 301 SEKPLVLSTSPFHPATHWKQALLYL 325 + LSTSP P+THWKQ + L Sbjct: 307 T-----LSTSPRSPSTHWKQTTILL 326 >5EKU-A nrPDB Length = 390 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 76/282 (26%), Positives = 121/282 (42%), Gaps = 27/282 (9%) Query: 57 HEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-A 115 H M+ D R + Y + ++ G VL++GAG+G+LS+ A+ GA+ V AVE S Sbjct: 72 HYAMMNDEERNNFYYEVLKKHVTPETG--VLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 129 Query: 116 IWQQAREVVRFNGLEDRV---HVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLH 172 + + ARE +R N +E +V H++ ++ LPE D ++SE G +L ES L V+ Sbjct: 130 LAKLARENIRANNMEHQVKVLHMMSTELKPKHLPEPPDVLLSEIFGTMMLGESALDYVVD 189 Query: 173 ARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMG 232 R + LK ++P + PI L R+ S + M L+ + Sbjct: 190 VRNRLLKPTTKIIPQFGTQYAVPIECDALH-RISSVSGWRDLDLKHMMTLQDTVSIVFAK 248 Query: 233 HSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGR--FRCSCYGSAPMHGFAI 290 H I + ++ L+ P +EL R + R F S H Sbjct: 249 HYGIRMNSVNFRR-LSDP-----IELFRVDFSSSNRNDISRRKHFDVVAKESGTAHAMLF 302 Query: 291 WFQVTFPGGESEKPLVLSTSP------FHPATHWKQALLYLN 326 +++VT + V+ST P F W QAL L+ Sbjct: 303 YWKVT------DDEFVMSTDPEDTVNNFPRDMQWGQALQLLD 338 >4M36-A nrPDB Length = 343 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 76/282 (26%), Positives = 122/282 (43%), Gaps = 27/282 (9%) Query: 57 HEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-A 115 H M+ D R + Y + ++ G VL++GAG+G+LS+ A+ GA+ V AVE S Sbjct: 37 HYAMMNDEERNNFYYEVLKKHVTPETG--VLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 94 Query: 116 IWQQAREVVRFNGLEDRV---HVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLH 172 + + ARE +R N +E +V H++ +++ LPE D ++SE G +L ES L V+ Sbjct: 95 LAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVD 154 Query: 173 ARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMG 232 R + LK ++P + PI L R+ S + M L+ + Sbjct: 155 VRNRLLKPTTKIIPQFGTQYAVPIECDALH-RISSVSGWRDLDLKHMMTLQDTVSIVFAK 213 Query: 233 HSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGR--FRCSCYGSAPMHGFAI 290 H I + ++ L+ P +EL R + R F S H Sbjct: 214 HYGIRMNSVNFRR-LSDP-----IELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLF 267 Query: 291 WFQVTFPGGESEKPLVLSTSP------FHPATHWKQALLYLN 326 +++VT + V+ST P F W QAL L+ Sbjct: 268 YWKVT------DDEFVMSTDPEDTVNNFPRDMQWGQALQLLD 303 >6OGN-A nrPDB Length = 692 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 48/184 (26%), Positives = 88/184 (47%), Gaps = 14/184 (7%) Query: 47 YYECYSDV--SVHEEMIADRVRTDAYRLGILRNWAALRGK----TVLDVGAGTGILSIFC 100 +Y+ + ++ S + +M+ D+ R Y GI + ++ + VLD+G GTG+LS+ Sbjct: 23 HYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMA 82 Query: 101 AQAGARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPVETV------ELPEQVDAIV 153 AGA YA+E + + A ++V NG D++ V+ V +LP + + ++ Sbjct: 83 VTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKVINKHSTEVTVGPDGDLPCRANILI 142 Query: 154 SEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPI-SDQMLEWRLGFWSQVK 212 +E L+ E L S HA ++E +P A ++ + S +M W F +V+ Sbjct: 143 TELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESRRMWSWNKLFPVRVR 202 Query: 213 QHYG 216 G Sbjct: 203 TSLG 206 >3X0D-A nrPDB Length = 655 Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 43/153 (28%), Positives = 73/153 (47%), Gaps = 9/153 (5%) Query: 59 EMIADRVRTDAYRLGILRNWAALR-----GKT-VLDVGAGTGILSIFCAQAGARRVYAVE 112 +MI D R D + G+ A + GK VLD+G GTG+LS+ A+ GA +V A+E Sbjct: 43 DMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALE 102 Query: 113 A-SAIWQQAREVVRFNGLEDRVHVLPGPVETVELP--EQVDAIVSEWMGYGLLHESMLSS 169 + AR + + D++ V+ V + D IV+E L+ E L + Sbjct: 103 VFKPMGDCARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRT 162 Query: 170 VLHARTKWLKEGGLLLPASAELFIAPISDQMLE 202 A + K G ++P++ ++I P+ +L+ Sbjct: 163 FKEALERLAKPGCRVVPSTGNVYIVPVESHLLK 195 >4G56-A nrPDB Length = 657 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Query: 84 KTVLDVGAGTGIL---SIFCAQAGARR--VYAVEASAIWQQAREVVRFNGLEDRVHVLPG 138 + ++ +GAG G L S+ A+ R+ VYAVE + E R+ +V V+ G Sbjct: 379 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 438 Query: 139 PVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD 198 + + PE+ D IVSE +G + L +LK+ G+ +P ++APIS Sbjct: 439 DMREWKAPEKADIIVSELLG-SFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS 497 Query: 199 QML 201 L Sbjct: 498 SKL 500 >4QNV-A nrPDB Length = 323 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Query: 66 RTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVR 125 R+D +L + + L G+T+LDVG G+G AGA ++ + ++ E VR Sbjct: 106 RSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVR 165 Query: 126 -FNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLL 184 G + R H+LP +E + + D + S MG S L + + + + EG L+ Sbjct: 166 KLLGNDQRAHLLPLGIEQLPALKAFDTVFS--MGVLYHRRSPLEHLWQLKDQLVNEGELV 223 Query: 185 L 185 L Sbjct: 224 L 224 >5FA5-A nrPDB Length = 650 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 6/123 (4%) Query: 84 KTVLDVGAGTGIL---SIFCAQAGARRV--YAVEASAIWQQAREVVRFNGLEDRVHVLPG 138 + ++ +GAG G L S+ A+ RR+ YAVE + E +F +V V+ Sbjct: 372 QVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSS 431 Query: 139 PVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD 198 + PE+ D IVSE +G + L +LK+ G+ +P F+APIS Sbjct: 432 DMREWVAPEKADIIVSELLG-SFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISS 490 Query: 199 QML 201 L Sbjct: 491 SKL 493 >2AS0-A nrPDB Length = 396 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 14/119 (11%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGP-- 139 G VLDV TG +I A AGA V ++ S + A+E + NG+EDR+ + G Sbjct: 218 GDRVLDVFTYTGGFAIHAAIAGADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSAF 277 Query: 140 --VETVELP-EQVDAIVSEWMGYGLLHESMLSSVLHAR-------TKWLKEGGLLLPAS 188 +E ++ E+ D +V + + + HE L + L A +K+GG+L+ S Sbjct: 278 EEMEKLQKKGEKFDIVVLDPPAF-VQHEKDLKAGLRAYFNVNFAGLNLVKDGGILVTCS 335 >3EGE-A nrPDB Length = 261 Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 11/105 (10%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVE 141 +G + D+GAGTG S+ A G VYAVE S + +Q V +V G E Sbjct: 34 KGSVIADIGAGTGGYSVALANQGL-FVYAVEPSIVMRQQAVV------HPQVEWFTGYAE 86 Query: 142 TVELPEQ-VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + LP++ VD ++S + H S L + +++G ++L Sbjct: 87 NLALPDKSVDGVISI---LAIHHFSHLEKSFQEMQRIIRDGTIVL 128 >1XDU-A nrPDB Length = 374 Score = 35.4 bits (80), Expect = 0.039, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 11/152 (7%) Query: 35 RPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTG 94 RP D + + + +E +A DAY +W+A+R VLDVG G G Sbjct: 143 RPFWEDLSADVALADSFDALMSCDEDLAYEAPADAY------DWSAVR--HVLDVGGGNG 194 Query: 95 -ILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIV 153 +L+ +A R VE + ++AR GL DRV V G LP D ++ Sbjct: 195 GMLAAIALRAPHLRGTLVELAGPAERARRRFADAGLADRVTVAEGDFFK-PLPVTADVVL 253 Query: 154 SEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 ++ E L ++L + L+ GG LL Sbjct: 254 LSFVLLNWSDEDAL-TILRGCVRALEPGGRLL 284 >3D2L-A nrPDB Length = 243 Score = 35.0 bits (79), Expect = 0.053, Method: Compositional matrix adjust. Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 10/107 (9%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHV--LPGPV 140 GK + D+G GTG ++ A Y V + ++ E+ + +E HV + Sbjct: 34 GKRIADIGCGTGTATLLLADH-----YEVTGVDLSEEMLEIAQEKAMETNRHVDFWVQDM 88 Query: 141 ETVELPEQVDA--IVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 +ELPE VDA I+ + + Y L E+ + + + L +GG LL Sbjct: 89 RELELPEPVDAITILCDSLNY-LQTEADVKQTFDSAARLLTDGGKLL 134 >4PNE-A nrPDB Length = 302 Score = 34.3 bits (77), Expect = 0.097, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 3/103 (2%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQ-AREVVRFNGLEDRVHVLPGPVE 141 G +LDVG GTG ++ A+ A ++ + S + A + R GL RV V+ Sbjct: 93 GVRLLDVGCGTGQPALRVARDNAIQITGITVSQVQVAIAADCARERGLSHRVDF--SCVD 150 Query: 142 TVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLL 184 + LP +A + W LL S + + LK GG+L Sbjct: 151 AMSLPYPDNAFDAAWAMQSLLEMSEPDRAIREILRVLKPGGIL 193 >4KRG-A nrPDB Length = 466 Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust. Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 14/152 (9%) Query: 40 KRERDQLYYECYSDVSVHEEMIADRVRTD---AYRLGILRNWAALRGKTVLDVGAGTGIL 96 +R+ + +++ YSD M+ ++ D + R IL + L K V+D+GAG G Sbjct: 12 RRDSFKTFWDKYSDKPDTNSMMLNQTAQDLEASDRADILSSLPHLTNKDVVDIGAGIGRF 71 Query: 97 SIFCAQAGARRVYA---VEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQ-VDAI 152 + A+ AR V + +E+ Q R N + G +++ E+ VD + Sbjct: 72 TTVLAET-ARWVLSTDFIESFIEKNQER-----NAHMGNISYQIGDAVHLQMDEKSVDLV 125 Query: 153 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLL 184 + W+ L ++ +L+A +WL+ G + Sbjct: 126 FTNWLMMYLSDREVIEFLLNA-MRWLRADGYI 156 >2R3S-A nrPDB Length = 335 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 86 VLDVGAGTGILSIFCAQAGAR-RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVE 144 VLD+ A G+ I AQ ++ V+ +++ + A+E R G+ R H + G V+ Sbjct: 169 VLDISASHGLFGIAVAQHNPNAEIFGVDWASVLEVAKENARIQGVASRYHTIAGSAFEVD 228 Query: 145 LPEQVDAIV 153 D ++ Sbjct: 229 YGNDYDLVL 237 >1WY7-A nrPDB Length = 207 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 13/87 (14%) Query: 69 AYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFN- 127 AY LG + GK V D+GAGTG+LS GA+ V VE ++A +V+ N Sbjct: 42 AYSLG------DIEGKVVADLGAGTGVLSYGALLLGAKEVICVEVD---KEAVDVLIENL 92 Query: 128 -GLEDRVHVLPGPVETVELPEQVDAIV 153 + + V G V E +VD ++ Sbjct: 93 GEFKGKFKVFIGDVS--EFNSRVDIVI 117 >6GKZ-A nrPDB Length = 351 Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust. Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 10/107 (9%) Query: 83 GKTVLDVGAGTGILSIFCAQAGAR-RVYAVEASAIWQQ--AREVVRFNGLEDRVHVLPGP 139 G++VLD+G G G L++ AQ RV AV S ++ E R N L V V Sbjct: 124 GQSVLDLGCGQGALTLHVAQKYKNCRVTAVTNSVSQKEYIEEESRRRNLL--NVEVKLAD 181 Query: 140 VETVELPEQVDAI-VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + T E+ E D I V E + +E +L + ++W+ + GLL Sbjct: 182 ITTHEMAETYDRILVIELFEHMKNYELLLRKI----SEWISKDGLLF 224 >3OPN-A nrPDB Length = 232 Score = 32.7 bits (73), Expect = 0.28, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEA 113 + GKT LD+G+ TG + Q GA+ VYA++ Sbjct: 36 INGKTCLDIGSSTGGFTDVMLQNGAKLVYALDV 68 >3DLC-A nrPDB Length = 219 Score = 32.3 bits (72), Expect = 0.37, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 8/83 (9%) Query: 77 NWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFN----GLEDR 132 N + T +D+G+G G LSI A+ + A++ S + E+ N L DR Sbjct: 38 NRFGITAGTCIDIGSGPGALSIALAKQSDFSIRALDFS---KHMNEIALKNIADANLNDR 94 Query: 133 VHVLPGPVETVELPEQ-VDAIVS 154 + ++ G V + + + D IVS Sbjct: 95 IQIVQGDVHNIPIEDNYADLIVS 117 >4KDR-A nrPDB Length = 223 Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 66 RTDAYRLGILRNWAA-LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVV 124 R + RLG + A L GK VLDVG G GIL A++ AR V + + +V Sbjct: 45 RINPLRLGYIAERAGGLFGKKVLDVGCGGGIL----AESMAREGATVTGLDMGFEPLQVA 100 Query: 125 RFNGLEDRVHV 135 + + LE + V Sbjct: 101 KLHALESGIQV 111 >3GXO-A nrPDB Length = 369 Score = 32.0 bits (71), Expect = 0.46, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 3/56 (5%) Query: 85 TVLDVGAGTGIL--SIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPG 138 T +D+G G G L ++ A G R +E + ++ARE++ GL DR +LPG Sbjct: 205 TAVDIGGGRGSLMAAVLDAFPGLRGTL-LERPPVAEEARELLTGRGLADRCEILPG 259 >1VQ1-A nrPDB Length = 294 Score = 32.0 bits (71), Expect = 0.50, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 7/59 (11%) Query: 84 KTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFN----GLEDRVHVLPG 138 KTV D+G G+G + + A+ V+A + S+ +A E+ R N G+ DR V G Sbjct: 135 KTVADIGTGSGAIGVSVAKFSDAIVFATDVSS---KAVEIARKNAERHGVSDRFFVRKG 190 >4KDC-A nrPDB Length = 246 Score = 31.6 bits (70), Expect = 0.52, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 66 RTDAYRLGILRNWAA-LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVV 124 R + RLG + A L GK VLDVG G GIL A++ AR V + + +V Sbjct: 45 RINPLRLGYIAERAGGLFGKKVLDVGCGGGIL----AESMAREGATVTGLDMGFEPLQVA 100 Query: 125 RFNGLEDRVHV 135 + + LE + V Sbjct: 101 KLHALESGIQV 111 >5WP5-A nrPDB Length = 491 Score = 31.6 bits (70), Expect = 0.65, Method: Compositional matrix adjust. Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 12/160 (7%) Query: 33 LERPRRTKRERDQLYY-ECYSDVSVHEEMIADRVRTD---AYRLGILRNWAALRGKTVLD 88 + P + +R+ + Y+ E SD++V E M+ D +D R +L GK+VL+ Sbjct: 1 MATPYKEERDIQKSYWMEHSSDLTV-EAMMLDSKASDLDKEERPEVLSLIPPYEGKSVLE 59 Query: 89 VGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQ 148 +GAG G + AQ A V A++ Q E V NG + + V + +L + Sbjct: 60 LGAGIGRFTGELAQK-AGEVIALDFIESAIQKNESV--NGHYKNIKFMCADVTSPDLKIK 116 Query: 149 ---VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 +D I S W+ L + + + W+K GG + Sbjct: 117 DGSIDLIFSNWL-LMYLSDKEVELMAERMIGWVKPGGYIF 155 >5BP9-A nrPDB Length = 281 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 76 RNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHV 135 R A+ T+LDVGAG+G ++ ++G + V A++ S + + EV++ G++D V Sbjct: 95 RTALAMATGTILDVGAGSGCHALALQESG-KEVSAIDISPL---SVEVMKLRGVKDARQV 150 >2AVN-A nrPDB Length = 260 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 27/54 (50%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGP 139 VLD+G GTG S+F + G V + + + ARE N +E + LP P Sbjct: 58 VLDLGGGTGKWSLFLQERGFEVVLVDPSKEMLEVAREKGVKNVVEAKAEDLPFP 111 >3V8V-A nrPDB Length = 702 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQ-AREVVRFNGLEDRVHVL 136 +GK L++ + TG ++ GAR V+ S + + A +R NGL R H L Sbjct: 538 KGKDFLNLFSYTGSATVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLTGRAHRL 593 >3CCF-A nrPDB Length = 279 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 19/105 (18%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVET 142 G+ +LD+G GTG L+ AQ+GA + A+ + ++AR+ +H Sbjct: 58 GEFILDLGCGTGQLTEKIAQSGAEVLGTDNAATMIEKARQNY------PHLHFDVADARN 111 Query: 143 VELPEQVDAIVSEWMGYGLLH-----ESMLSSVLHARTKWLKEGG 182 + + +DA+ S +LH E+ ++S+ A LK GG Sbjct: 112 FRVDKPLDAVFSN----AMLHWVKEPEAAIASIHQA----LKSGG 148 >4P7C-A nrPDB Length = 322 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 13/111 (11%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPG-- 138 L+GK VLDVG G G AGA V V+ + ++ +F ++ + LP Sbjct: 120 LKGKRVLDVGCGNGYYQWRMLGAGADSVIGVDPNWLF-----FCQFQAMQRYLPDLPAWH 174 Query: 139 -PVETVELP---EQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 P +LP E D + S MG +S + +L + +K G L++ Sbjct: 175 LPFALEDLPANLEGFDTVFS--MGVLYHRKSPIDHLLALKDCLVKGGELVM 223 >4QPN-A nrPDB Length = 227 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 17/24 (70%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAG 104 RGK V+++GAGTGI+ I A G Sbjct: 75 FRGKKVIELGAGTGIVGILAALQG 98 >5I2H-A nrPDB Length = 364 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 9/116 (7%) Query: 74 ILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR-RVYAVEASAIWQQAREVVRFNGLEDR 132 IL++ + G+ +LDV G+GI ++ Q R + + + A E+ G+ DR Sbjct: 188 ILKDNSGSSGRVLLDVAGGSGIYTMAVLQKYPTWRGIIFDRPEVLKIAAELAEQTGVRDR 247 Query: 133 VHVLPGPVETVELPEQVDAIVSEWMGYGLLHE---SMLSSVLHARTKWLKEGGLLL 185 + + G + P D ++S +LH+ + ++ T L EGG LL Sbjct: 248 LELHAGDMWVDPFPPADDILLSN-----VLHDWDRPQCARLVAKATSGLPEGGRLL 298 >5Z9O-A nrPDB Length = 399 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 74 ILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-AIWQQAREVVRFNGLEDR 132 IL +GKT+LD+G G G L + A+ +V V S ++ ++ + GLED Sbjct: 157 ILNKLHPEKGKTLLDIGCGWGTLMLTAAKEYGLKVTGVTLSEEQYKLVQKKIYDEGLEDV 216 Query: 133 VHV 135 V Sbjct: 217 AEV 219 >4X3Q-A nrPDB Length = 355 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 82 RGKTVLDVGAGTGILSIFCAQAG-ARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPV 140 R VLDVG G + ++ A+A + RV ++ + AR+ + GLE+RV + Sbjct: 170 RVHRVLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADI 229 Query: 141 ETVELPEQVDAIV 153 T P D ++ Sbjct: 230 FTDSYPAGHDCVL 242 >3LEC-A nrPDB Length = 230 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 9/116 (7%) Query: 71 RLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAI---WQQAREVVRFN 127 RL + N+ +G +LDVG+ L IF Q G +A+ + +Q A + V + Sbjct: 11 RLQKVANYVP-KGARLLDVGSDHAYLPIFLLQMGYCD-FAIAGEVVNGPYQSALKNVSEH 68 Query: 128 GLEDRVHV-LPGPVETVELPEQVDAIVSEWMGYGLLHESM---LSSVLHARTKWLK 179 GL ++ V L + E + +D I MG L+ + + + + H +T L+ Sbjct: 69 GLTSKIDVRLANGLSAFEEADNIDTITICGMGGRLIADILNNDIDKLQHVKTLVLQ 124 >5Y27-B nrPDB Length = 92 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 17 GGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSD---VSVHEEMIADRVRTDAYRLG 73 G G+ E+ + L R +R ++ + ++Y + +SV E+ +++ T+AY+L Sbjct: 1 GPLGSMEKTYGKTVLPLSRVKRIIKQDEDVHYCSNASALLISVATELFVEKLATEAYQLA 60 Query: 74 ILRNWAALRGKTVLDV 89 L+ +R + V DV Sbjct: 61 KLQKRKGIRYRDVEDV 76 >3DMF-A nrPDB Length = 381 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 20/28 (71%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRV 108 +RG+ VLD+GAG G L++ A+ GA V Sbjct: 232 VRGRQVLDLGAGYGALTLPLARMGAEVV 259 >4LEC-A nrPDB Length = 212 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 19/26 (73%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGAR 106 LRG++ +++GAGTG++ I A GA Sbjct: 58 LRGRSAVELGAGTGLVGIVAALLGAH 83 >6QDV-c nrPDB Length = 586 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 13/54 (24%), Positives = 25/54 (46%) Query: 203 WRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQL 256 W+ G W H S G A + ++ E ++ ++GE+ + +PQ +L Sbjct: 436 WKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMEL 489 >2PJD-A nrPDB Length = 343 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 43/141 (30%), Positives = 65/141 (46%), Gaps = 21/141 (14%) Query: 82 RGKTVLDVGAGTGILSI-FCAQAGARRVYAVEASAIWQQA-REVVRFNGLEDRVHVLPGP 139 +GK VLDVG G G+LS+ F + R+ + SA +A R + NG+E V Sbjct: 197 KGK-VLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEGEVF---AS 252 Query: 140 VETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART------KWLKEGG-LLLPASAELF 192 E+ + D I+S H+ M +S+ A+T + L GG L + A+A L Sbjct: 253 NVFSEVKGRFDMIISN----PPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFL- 307 Query: 193 IAPISDQMLEWRLGFWSQVKQ 213 P D +L+ GF + Q Sbjct: 308 --PYPD-VLDETFGFHEVIAQ 325 >3R9X-B nrPDB Length = 248 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 19/30 (63%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVE 112 G TV++VG GTG L+ Q +++Y +E Sbjct: 31 GNTVVEVGGGTGNLTKVLLQHPLKKLYVIE 60 >1R74-A nrPDB Length = 294 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 7/54 (12%) Query: 64 RVRTDAYR---LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS 114 R RT Y+ LG+LR R VLDV GTG+ SI + G V +V+AS Sbjct: 38 RSRTAEYKAWLLGLLRQHGCQR---VLDVACGTGVDSIMLVEEGF-SVTSVDAS 87 >3CJR-A nrPDB Length = 254 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 25/50 (50%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDR 132 G VLD+G G+G+L+I + G + + + QA + NG+ R Sbjct: 121 GDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRNGVRPR 170 >4HJW-A nrPDB Length = 378 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 11/95 (11%) Query: 187 ASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGE-- 244 A A +++A + DQ+ + R+ V H G + L G C+ ++V QG GE Sbjct: 230 AVARMYLAGVFDQVRDLRM-----VLAHSGGTLPFLAGRIESCIFHDGQLVRQGKVGENR 284 Query: 245 ----DVLARPQRFAQLELSRAGLEQELEAGVGGRF 275 DVL + S GL+ ++A R Sbjct: 285 RTVWDVLKEQVYLDAVIYSEVGLKAAIDASGSDRL 319 >3HP7-A nrPDB Length = 291 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 12/99 (12%) Query: 87 LDVGAGTGILSIFCAQAGARRVYAVEASA---IWQQAREVVRFNGLEDRVHVLPGPVETV 143 +D+GA TG + Q GA+ VYAV+ +W + R+ R +E PV+ Sbjct: 90 IDIGASTGGFTDVMLQNGAKLVYAVDVGTNQLVW-KLRQDDRVRSMEQYNFRYAEPVDFT 148 Query: 144 ELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGG 182 E +I ++ L +L A K L +GG Sbjct: 149 EGLPSFASIDVSFISLNL--------ILPALAKILVDGG 179 >1D2C-A nrPDB Length = 292 Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust. Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 7/54 (12%) Query: 64 RVRTDAYR---LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS 114 R RT Y+ LG+LR R VLDV GTG+ SI + G V +V+AS Sbjct: 38 RSRTAEYKAWLLGLLRQHGCHR---VLDVACGTGVDSIMLVEEGF-SVTSVDAS 87 >3BUS-A nrPDB Length = 273 Score = 28.1 bits (61), Expect = 6.9, Method: Compositional matrix adjust. Identities = 39/146 (26%), Positives = 61/146 (41%), Gaps = 11/146 (7%) Query: 52 SDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAV 111 +DVSV + DR+ + L +R+ G VLDVG G G ++ A A RV + Sbjct: 38 ADVSVDDAT--DRLTDEMIALLDVRS-----GDRVLDVGCGIGKPAVRLATARDVRVTGI 90 Query: 112 EAS-AIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSV 170 S QA GL +RV + ++LP + + + W L H Sbjct: 91 SISRPQVNQANARATAAGLANRVTF--SYADAMDLPFEDASFDAVWALESLHHMPDRGRA 148 Query: 171 LHARTKWLKEGGLLLPASAELFIAPI 196 L + L+ GG + A + +AP+ Sbjct: 149 LREMARVLRPGGTVAIADF-VLLAPV 173 >5JE5-A nrPDB Length = 247 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGP 139 + GK+VLD+ G G + GA +V V+ S + + ARE R G HV Sbjct: 40 VSGKSVLDLACGFGFFGREIYRRGAAKVVGVDISEKMIELAREESRKYGDPLEFHVR--D 97 Query: 140 VETVELPEQVDAIVSEWM 157 V +E Q D + + W+ Sbjct: 98 VANMEPLGQFDLVNAAWL 115 >3BKX-A nrPDB Length = 275 Score = 27.7 bits (60), Expect = 8.2, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 19/36 (52%) Query: 66 RTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCA 101 R A+RL I W G+ +L++G G G LS A Sbjct: 27 RQTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLA 62 >4QDJ-A nrPDB Length = 238 Score = 27.3 bits (59), Expect = 10.0, Method: Compositional matrix adjust. Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 6/51 (11%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-----AIWQQAREVVRF 126 L G V D G G G LSI AQAGA VY + S Q+A+EV+ + Sbjct: 61 LPGLLVCDAGCGVGSLSIPLAQAGA-LVYGSDISEKMVGEAQQKAQEVLAY 110 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5EGS-A nrPDB 555 e-158 5LV5-A nrPDB 511 e-145 3Q7E-A nrPDB 408 e-114 4RYL-A nrPDB 399 e-112 5DST-A nrPDB 396 e-111 1F3L-A nrPDB 394 e-110 5JMQ-A nrPDB 385 e-107 1G6Q-1 nrPDB 382 e-106 6CU3-A nrPDB 382 e-106 5FUB-A nrPDB 381 e-106 3R0Q-C nrPDB 350 5e-97 3B3J-A nrPDB 343 7e-95 5IS8-A nrPDB 341 3e-94 4IKP-A nrPDB 341 3e-94 5EKU-A nrPDB 251 3e-67 4M36-A nrPDB 250 9e-67 4LWO-B nrPDB 248 2e-66 6OGN-A nrPDB 205 3e-53 3X0D-A nrPDB 171 6e-43 4G56-A nrPDB 153 1e-37 5FA5-A nrPDB 149 2e-36 4QNV-A nrPDB 129 2e-30 Sequences not found previously or not previously below threshold: 4P7C-A nrPDB 91 1e-18 3UA4-A nrPDB 87 1e-17 5Z9O-A nrPDB 52 5e-07 1L3B-A nrPDB 51 9e-07 2AS0-A nrPDB 49 2e-06 3SVZ-A nrPDB 47 1e-05 1WY7-A nrPDB 47 1e-05 3DLC-A nrPDB 47 1e-05 3D2L-A nrPDB 46 2e-05 4KRG-A nrPDB 46 3e-05 3EGE-A nrPDB 46 4e-05 5WP5-A nrPDB 45 5e-05 3A26-A nrPDB 45 7e-05 5JE5-A nrPDB 44 7e-05 1XDU-A nrPDB 44 1e-04 4LG1-A nrPDB 44 1e-04 2ZZN-A nrPDB 44 1e-04 4KDR-A nrPDB 43 2e-04 4PNE-A nrPDB 43 2e-04 4KDC-A nrPDB 43 2e-04 3LPM-A nrPDB 43 2e-04 6BQC-A nrPDB 43 3e-04 3BKW-A nrPDB 42 3e-04 1RI1-A nrPDB 42 3e-04 5YAC-A nrPDB 42 5e-04 5WP4-A nrPDB 42 5e-04 2XVM-A nrPDB 42 6e-04 1KP9-A nrPDB 42 6e-04 5FAD-A nrPDB 41 8e-04 5BP9-A nrPDB 41 8e-04 5H02-A nrPDB 41 0.001 4QPN-A nrPDB 41 0.001 3CCF-A nrPDB 41 0.001 4O29-A nrPDB 41 0.001 3GU3-A nrPDB 40 0.002 5GM1-A nrPDB 40 0.002 3CJR-A nrPDB 40 0.002 4FS8-A nrPDB 39 0.003 6GKZ-A nrPDB 39 0.004 2AVN-A nrPDB 39 0.005 5I2H-A nrPDB 39 0.005 2PJD-A nrPDB 38 0.006 1DUS-A nrPDB 38 0.007 1DL5-A nrPDB 38 0.007 1NKV-A nrPDB 38 0.008 1VQ1-A nrPDB 37 0.009 2YXD-A nrPDB 37 0.009 4QDJ-A nrPDB 37 0.010 6AW7-A nrPDB 37 0.013 3NJR-A nrPDB 37 0.016 2ZLB-A nrPDB 37 0.017 5BP7-A nrPDB 37 0.019 3DMF-A nrPDB 36 0.022 3BUS-A nrPDB 36 0.022 3I9F-A nrPDB 36 0.025 3P9N-A nrPDB 36 0.030 6DCC-A nrPDB 36 0.031 2I6G-A nrPDB 35 0.037 3GXO-A nrPDB 35 0.038 1YUB-A nrPDB 35 0.045 4HGY-A nrPDB 35 0.046 5EVJ-A nrPDB 35 0.057 4HTF-A nrPDB 35 0.058 3MGG-A nrPDB 35 0.069 4KRI-A nrPDB 34 0.087 5U19-A nrPDB 34 0.090 6MRO-A nrPDB 34 0.10 2GPY-A nrPDB 34 0.11 2YVL-A nrPDB 34 0.11 1DOH-A nrPDB 34 0.12 3C3P-A nrPDB 34 0.13 3SM3-A nrPDB 34 0.14 5IKM-A nrPDB 34 0.15 3TFW-A nrPDB 34 0.15 3OPN-A nrPDB 34 0.16 5BXY-A nrPDB 34 0.16 2IP2-A nrPDB 33 0.17 3VC2-A nrPDB 33 0.20 5MGZ-A nrPDB 33 0.23 3GRV-A nrPDB 33 0.25 3FYD-A nrPDB 33 0.25 5M58-A nrPDB 33 0.25 1R74-A nrPDB 33 0.27 4NEC-A nrPDB 32 0.30 4LEC-A nrPDB 32 0.30 4F86-A nrPDB 32 0.34 5EHG-A nrPDB 32 0.36 3BKX-A nrPDB 32 0.36 2VS1-A nrPDB 32 0.38 2YXE-A nrPDB 32 0.40 1XCL-A nrPDB 32 0.40 2ESR-A nrPDB 32 0.42 4PLP-A nrPDB 32 0.51 6C4I-N nrPDB 32 0.52 4V0R-A nrPDB 32 0.54 4WXH-A nrPDB 32 0.56 1ZQ9-A nrPDB 32 0.58 3HP7-A nrPDB 32 0.60 5XFM-A nrPDB 32 0.61 4FGZ-A nrPDB 32 0.61 1D2C-A nrPDB 31 0.72 3E23-A nrPDB 31 0.74 1P1B-A nrPDB 31 0.80 1I9G-A nrPDB 31 0.80 2B25-A nrPDB 31 0.85 3BXO-A nrPDB 31 0.86 6C5B-A nrPDB 31 0.88 1UWV-A nrPDB 31 0.89 6M83-A nrPDB 31 0.92 4AZW-A nrPDB 30 1.1 3MQ2-A nrPDB 30 1.1 4AZV-A nrPDB 30 1.3 5F8E-A nrPDB 30 1.4 3G7U-A nrPDB 30 1.4 2GLU-A nrPDB 30 1.6 2GS9-A nrPDB 30 1.6 2YR0-A nrPDB 30 1.6 6FDU-A nrPDB 30 1.7 3M70-A nrPDB 30 1.7 1RQX-A nrPDB 30 1.8 2FHP-A nrPDB 30 1.9 5J3E-A nrPDB 30 2.0 2B3T-A nrPDB 30 2.1 2OXT-A nrPDB 30 2.3 5XS0-A nrPDB 29 2.7 4DCM-A nrPDB 29 2.8 4MTL-A nrPDB 29 3.5 6F5Z-A nrPDB 29 4.4 3G5T-A nrPDB 28 8.8 >5EGS-A nrPDB Length = 376 Score = 555 bits (1430), Expect = e-158, Method: Composition-based stats. Identities = 374/375 (99%), Positives = 374/375 (99%) Query: 1 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM 60 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM Sbjct: 2 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM 61 Query: 61 IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA 120 IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA Sbjct: 62 IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA 121 Query: 121 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE 180 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE Sbjct: 122 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE 181 Query: 181 GGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG 240 GGLLLPASAELFI PISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG Sbjct: 182 GGLLLPASAELFIVPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG 241 Query: 241 LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE 300 LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE Sbjct: 242 LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE 301 Query: 301 SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK 360 SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK Sbjct: 302 SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK 361 Query: 361 VGDQEEKTKDFAMED 375 VGDQEEKTKDFAMED Sbjct: 362 VGDQEEKTKDFAMED 376 >5LV5-A nrPDB Length = 403 Score = 511 bits (1316), Expect = e-145, Method: Composition-based stats. Identities = 336/378 (88%), Positives = 349/378 (92%), Gaps = 3/378 (0%) Query: 1 MSQPKKRKLESGGGGEGGEGTEEEDGAEREA---ALERPRRTKRERDQLYYECYSDVSVH 57 MS KKRKLESG G G G E + A RPRRTK ERDQLYYECYSDVSVH Sbjct: 26 MSLSKKRKLESGDSGGAGAGGEGAEEENGGEQEAAPPRPRRTKSERDQLYYECYSDVSVH 85 Query: 58 EEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW 117 EEMIAD+VRT+AYRLGIL+NWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW Sbjct: 86 EEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW 145 Query: 118 QQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKW 177 QQAREVVR NGLEDRVHVLPGPVETVELPE+VDAIVSEWMGYGLLHESMLSSVLHARTKW Sbjct: 146 QQAREVVRLNGLEDRVHVLPGPVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKW 205 Query: 178 LKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIV 237 LKEGGLLLPASAELF+APISDQMLEWRLGFWSQVKQHYGVDMSC+E FATRCLMGHSEIV Sbjct: 206 LKEGGLLLPASAELFVAPISDQMLEWRLGFWSQVKQHYGVDMSCMESFATRCLMGHSEIV 265 Query: 238 VQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFP 297 VQ LSGEDVLARPQRFAQLEL+RAGLEQELEAGVGGRFRCSCYGSAP+HGFA+WFQVTFP Sbjct: 266 VQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFP 325 Query: 298 GGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLL 357 GG+SEKPLVLSTSP HPATHWKQALLYLNEPV VEQDTD+SGEITLLPS DNPRRLR+LL Sbjct: 326 GGDSEKPLVLSTSPLHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILL 385 Query: 358 RYKVGDQEEKTKDFAMED 375 RYKVGD EEKTKDFAMED Sbjct: 386 RYKVGDHEEKTKDFAMED 403 >3Q7E-A nrPDB Length = 349 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 114/342 (33%), Positives = 178/342 (52%), Gaps = 16/342 (4%) Query: 31 AALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVG 90 + E+P Y++ Y+ +HEE++ D VRT YR + N + K VLDVG Sbjct: 15 ESSEKPNAEDMTSKDYYFDSYAHFGIHEELLKDEVRTLTYRNSMFHNRHLFKDKVVLDVG 74 Query: 91 AGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQV 149 +GTGIL +F A+AGAR+V +E S+I A ++V+ N L+ V ++ G VE VELP E+V Sbjct: 75 SGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKV 134 Query: 150 DAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFW 208 D I+SEWMGY L +ESML++VLHAR KWL GL+ P A L++ I D Q ++++ +W Sbjct: 135 DIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWW 194 Query: 209 SQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELE 268 V YG DMSC++ A + E +V + + ++ ++++ +E + Sbjct: 195 ENV---YGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVKVE---D 242 Query: 269 AGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEP 328 F + +H +F + F K STSP P THWKQ + Y+ + Sbjct: 243 LTFTSPFCLQVKRNDYVHALVAYFNIEFT--RCHKRTGFSTSPESPYTHWKQTVFYMEDY 300 Query: 329 VQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKD 370 + V+ ++ G I + P+ N R L + Q + Sbjct: 301 LTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSC 342 >4RYL-A nrPDB Length = 340 Score = 399 bits (1025), Expect = e-112, Method: Composition-based stats. Identities = 113/334 (33%), Positives = 175/334 (52%), Gaps = 15/334 (4%) Query: 33 LERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAG 92 + R + + D +Y+ Y +HEEM+ D++RT++YR I +N + K VLDVG G Sbjct: 15 VPRGSDLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCG 74 Query: 93 TGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDA 151 TGILS+F A+AGA++V V+ S I QA +++R N LED + ++ G +E V LP E+VD Sbjct: 75 TGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDV 134 Query: 152 IVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQ 210 I+SEWMGY LL ESML SVL+A+ K+L +GG + P + + +SD R+ FW Sbjct: 135 IISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDD 194 Query: 211 VKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAG 270 V YG MSC++ E VV+ L + +++ P ++ + + Sbjct: 195 V---YGFKMSCMKKAVI------PEAVVEVLDPKTLISEPCGIKHIDCHTTSIS---DLE 242 Query: 271 VGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQ 330 F ++ A +F + F +V ST P THWKQ + L +P Sbjct: 243 FSSDFTLKITRTSMCTAIAGYFDIYFE-KNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFS 301 Query: 331 VEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQ 364 V+ + G++T+ ++ +PR L V L Q Sbjct: 302 VKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQ 335 >5DST-A nrPDB Length = 332 Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats. Identities = 114/340 (33%), Positives = 183/340 (53%), Gaps = 19/340 (5%) Query: 39 TKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSI 98 + Y++ Y+ +HEEM+ D VRT YR + N + K VLDVG+GTGILS+ Sbjct: 6 EEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSM 65 Query: 99 FCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWM 157 F A+AGA++V+ +E S+I + ++++ N L++ + + G VE VELP E+VD I+SEWM Sbjct: 66 FAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWM 125 Query: 158 GYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYG 216 GY L +ESML++V+ AR KWLK GGL+ P A L++ I D Q ++++ +W V YG Sbjct: 126 GYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENV---YG 182 Query: 217 VDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFR 276 DM+C+ A + E +V + + V+ ++++ E E F Sbjct: 183 FDMTCIRDVAMK------EPLVDIVDPKQVVTNACLIKEVDIYTVKTE---ELSFTSAFC 233 Query: 277 CSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTD 336 + +H +F + F + K + ST+P P THWKQ + YL + + V + + Sbjct: 234 LQIQRNDYVHALVTYFNIEFT--KCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEE 291 Query: 337 VSGEITLLPSRDNPRRLRVLLRYKVGDQEEKT---KDFAM 373 + G I++ P+ N R L + Q +T D+ M Sbjct: 292 IYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKM 331 >1F3L-A nrPDB Length = 321 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 115/329 (34%), Positives = 176/329 (53%), Gaps = 15/329 (4%) Query: 38 RTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILS 97 + + D +Y+ Y +HEEM+ D+VRT++YR I +N + K VLDVG GTGILS Sbjct: 1 DLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 60 Query: 98 IFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEW 156 +F A+AGA++V AV+ S I QA +++R N LED + ++ G +E V LP E+VD I+SEW Sbjct: 61 MFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEW 120 Query: 157 MGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLE-WRLGFWSQVKQHY 215 MGY LL ESML SVL+A++K+L +GG + P + + +SD R+ FW V Y Sbjct: 121 MGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDV---Y 177 Query: 216 GVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRF 275 G +MSC++ E VV+ + + +++ P ++ + + F Sbjct: 178 GFNMSCMKKAVI------PEAVVEVVDHKTLISDPCDIKHIDCHTTSIS---DLEFSSDF 228 Query: 276 RCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDT 335 +A A +F + F +V ST P THWKQ + L +P V+ Sbjct: 229 TLRTTKTAMCTAVAGYFDIYFE-KNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGE 287 Query: 336 DVSGEITLLPSRDNPRRLRVLLRYKVGDQ 364 + G+IT+ ++ +PR L V L Q Sbjct: 288 ALKGKITVHKNKKDPRSLIVTLTLNSSTQ 316 >5JMQ-A nrPDB Length = 446 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 125/342 (36%), Positives = 180/342 (52%), Gaps = 9/342 (2%) Query: 30 EAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDV 89 LE +D+ Y++ Y + +H EM+AD+ RT Y IL+N +L+ K +LDV Sbjct: 98 GKQLEEYDPEDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDV 157 Query: 90 GAGTGILSIFCAQ-AGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQ 148 G GTGI+S+FCA A + VYAVEAS + Q ++V NG D + V VE V LPE+ Sbjct: 158 GCGTGIISLFCAHHARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVVLPEK 217 Query: 149 VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPIS-DQMLEWRLGF 207 VD +VSEWMG LL E M+ S+L+AR WLK G++ P +A L + P S ++ ++ F Sbjct: 218 VDVLVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLF 277 Query: 208 WSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQEL 267 W Y ++S L+ A + + L ED L+ P QL++ + +L Sbjct: 278 WDNA---YEFNLSALKSLAIKEFFSRPKS-NHILKPEDCLSEPCTILQLDMRTVQV-PDL 332 Query: 268 EAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKP-LVLSTSPFHPATHWKQALLYLN 326 E + G R + +HGF WF V F E +P VLST P HP THWKQ L ++ Sbjct: 333 ET-MRGELRFDIQKAGTLHGFTAWFSVYFQSLEEGQPQQVLSTGPLHPTTHWKQTLFMMD 391 Query: 327 EPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKT 368 +PV V V+G + L + R + V L + V + T Sbjct: 392 DPVPVHTGDVVTGSVVLQRNPVWRRHMSVSLSWVVTSALDPT 433 >1G6Q-1 nrPDB Length = 328 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 112/321 (34%), Positives = 172/321 (53%), Gaps = 14/321 (4%) Query: 45 QLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAG 104 Y++ Y +HEEM+ D VRT +YR I++N + K VLDVG GTGILS+F A+ G Sbjct: 1 DYYFDSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHG 60 Query: 105 ARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMGYGLLH 163 A+ V V+ S+I + A+E+V NG D++ +L G +E V LP +VD I+SEWMGY LL+ Sbjct: 61 AKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLY 120 Query: 164 ESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGVDMSCL 222 ESM+ +VL+AR +L EGGL+ P + +A + D Q + +L +W V YG D S Sbjct: 121 ESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDV---YGFDYS-- 175 Query: 223 EGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGS 282 F L E +V + +V + + +L+ + + F+ + Sbjct: 176 -PFVPLVL---HEPIVDTVERNNVNTTSDKLIEFDLNTVKIS---DLAFKSNFKLTAKRQ 228 Query: 283 APMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEIT 342 ++G WF + FP + ++P+ ST P P THWKQ + Y + + E + GE+ Sbjct: 229 DMINGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELV 288 Query: 343 LLPSRDNPRRLRVLLRYKVGD 363 P+ N R L + + YK Sbjct: 289 CSPNEKNNRDLNIKISYKFES 309 >6CU3-A nrPDB Length = 336 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 112/324 (34%), Positives = 177/324 (54%), Gaps = 17/324 (5%) Query: 55 SVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS 114 +HEEM+ D +RT+AY+ IL+N + K VLD+G GTGIL +F A+AGA+RV ++ S Sbjct: 24 GIHEEMLKDGIRTNAYKNAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAKRVIGIDMS 83 Query: 115 AIWQQAREVVRFNGLEDRVHVLPGPVETV-ELP---EQVDAIVSEWMGYGLLHESMLSSV 170 I +AR++V NG + ++ G VE + +LP E+VD I+SEWMGY LL+ESML +V Sbjct: 84 DIIDKARQIVSDNGYSHVIELIKGKVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQTV 143 Query: 171 LHARTKWLKEGGLLLPASAELFIAPISDQMLEW-RLGFWSQVKQHYGVDMSCLEGFATRC 229 L AR +WL+ GG L P ++I I D + ++ FW V YG + S ++ A R Sbjct: 144 LSARDRWLRPGGYLFPDKCTMYICGIEDSEYKRDKIDFWDNV---YGFNFSAIKADALR- 199 Query: 230 LMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFA 289 E +V + + ++ +F +++L+ ++ E + F + F Sbjct: 200 -----EPLVDFVESQQIITTQSKFLEIDLNT--IQPEDLKQITTSFEFTSQYQEYCQAFV 252 Query: 290 IWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDN 349 WF F G KP+ ST PF THWKQ + YL + ++ + + G IT+ ++ N Sbjct: 253 AWFDCVFSRG-PHKPVEFSTGPFTEGTHWKQTVFYLENDLPLKPNDVIKGTITISQNKSN 311 Query: 350 PRRLRVLLRYKVGDQEEKTKDFAM 373 R L + ++Y V ++D+ M Sbjct: 312 HRDLDISMKYTVNGGAVISQDYIM 335 >5FUB-A nrPDB Length = 337 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 127/337 (37%), Positives = 181/337 (53%), Gaps = 12/337 (3%) Query: 43 RDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQ 102 +D Y+ Y + +H EM++D+ RT+ YR IL N AALR K VLD+G GTG++S+FCA Sbjct: 5 QDDEYFGNYGTLRLHLEMLSDKPRTETYRQVILSNSAALREKVVLDLGCGTGVISLFCAL 64 Query: 103 -AGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGL 161 A VYAVEAS++ + E+V+ NG + V V E + LP +VD +VSEWMG L Sbjct: 65 LAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENLTLPTKVDVLVSEWMGNCL 124 Query: 162 LHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGVDMS 220 L E ML SVL AR +WLK+GG++ P+SA L I P ++ FW YG++ S Sbjct: 125 LFEYMLESVLLARDRWLKKGGMMWPSSACLTIVPCQAFSDYRQKVEFWEN---PYGLNFS 181 Query: 221 CLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCY 280 L+ A + + + L ED L+ P L++ + +LE + G F + Sbjct: 182 YLQSLAQKEFLSKPKFS-HHLQPEDCLSTPADVITLDMVTIQV-SDLER-LKGEFTFTVE 238 Query: 281 GSAPMHGFAIWFQVTFPGGESEKP-LVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSG 339 S HGF +WF F E + P + L+T P+ THWKQ L L+ PV VE+ ++G Sbjct: 239 KSGMFHGFTVWFSAHFQCLEEDGPSIELNTGPYSEITHWKQTLFMLDAPVSVEEGDIIAG 298 Query: 340 EITLLPSRDNPRRLRVLLRYKVGDQE---EKTKDFAM 373 I L + R L + + + E KTK F M Sbjct: 299 SIRLQRNPIWRRHLSITFLWNINSTEVSTVKTKCFPM 335 >3R0Q-C nrPDB Length = 376 Score = 350 bits (898), Expect = 5e-97, Method: Composition-based stats. Identities = 116/345 (33%), Positives = 190/345 (55%), Gaps = 23/345 (6%) Query: 40 KRERDQLYYEC-YSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSI 98 +E D Y C YS + ++M++DRVR DAY + +N GKTVLDVG G+GIL+I Sbjct: 20 DKEVDYAQYFCTYSFLYHQKDMLSDRVRMDAYFNAVFQNKHHFEGKTVLDVGTGSGILAI 79 Query: 99 FCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMG 158 + AQAGAR+VYAVEA+ + AR +V+ N L+ V V+ G VE + LPE+VD I+SEWMG Sbjct: 80 WSAQAGARKVYAVEATKMADHARALVKANNLDHIVEVIEGSVEDISLPEKVDVIISEWMG 139 Query: 159 YGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRL-----------GF 207 Y LL ESM SV+ AR +WLK G++ P+ A +++API + + + F Sbjct: 140 YFLLRESMFDSVISARDRWLKPTGVMYPSHARMWLAPIKSNIADRKRNDFDGAMADWHNF 199 Query: 208 WSQVKQHYGVDMSCL-EGFATRCLMGHSEIVV-QGLSGEDVLARPQRFAQLELSRAGLE- 264 ++K +YGVDM L + FA + + + L+ + ++ P +++ A + Sbjct: 200 SDEIKSYYGVDMGVLTKPFAEEQEKYYIQTAMWNDLNPQQIIGTPTIVKEMDCLTASVSE 259 Query: 265 -QELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESE---KPLVLSTSP-FHPATHWK 319 +E+ + V + GF WF V F G + + + + L+T+P THW Sbjct: 260 IEEVRSNVTSVINM---EHTRLCGFGGWFDVQFSGRKEDPAQQEIELTTAPSEQHCTHWG 316 Query: 320 QALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQ 364 Q + ++ P+ VE+ +++ + + S++N R + + L ++ + Sbjct: 317 QQVFIMSNPINVEEGDNLNLGLLMSRSKENHRLMEIELNCEIKEA 361 >3B3J-A nrPDB Length = 480 Score = 343 bits (880), Expect = 7e-95, Method: Composition-based stats. Identities = 125/335 (37%), Positives = 175/335 (52%), Gaps = 18/335 (5%) Query: 29 REAALERP---RRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKT 85 R LER RT+ Y++ Y +S + M+ D VRT Y+ IL+N + K Sbjct: 102 RGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKI 161 Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVEL 145 VLDVG G+GILS F AQAGAR++YAVEAS + Q A +V+ N L DR+ V+PG VE V L Sbjct: 162 VLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSL 221 Query: 146 PEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW-- 203 PEQVD I+SE MGY L +E ML S LHA+ K+LK G + P ++ +AP +D+ L Sbjct: 222 PEQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQ 280 Query: 204 --RLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLEL-SR 260 + FW Q H GVD+S L G A + VV ++A+ ++ L ++ Sbjct: 281 FTKANFWYQPSFH-GVDLSALRGAAVDEYF--RQPVVDTFDIRILMAKSVKYTVNFLEAK 337 Query: 261 AGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQ 320 G +E F+ S +HG A WF V F G S + LST+P P THW Q Sbjct: 338 EGDLHRIEIP----FKFHMLHSGLVHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQ 391 Query: 321 ALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRV 355 P+ + +SG L+ ++ + + Sbjct: 392 VRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISI 426 >5IS8-A nrPDB Length = 381 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 124/334 (37%), Positives = 174/334 (52%), Gaps = 18/334 (5%) Query: 30 EAALERP---RRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTV 86 LER RT+ Y++ Y +S + M+ D VRT Y+ IL+N + K V Sbjct: 4 GHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIV 63 Query: 87 LDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP 146 LDVG G+GILS F AQAGAR++YAVEAS + Q A +V+ N L DR+ V+PG VE V LP Sbjct: 64 LDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP 123 Query: 147 EQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW--- 203 EQVD I+SE MGY L +E ML S LHA+ K+LK G + P ++ +AP +D+ L Sbjct: 124 EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQF 182 Query: 204 -RLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLEL-SRA 261 + FW Q H GVD+S L G A + VV ++A+ ++ L ++ Sbjct: 183 TKANFWYQPSFH-GVDLSALRGAAVDEYF--RQPVVDTFDIRILMAKSVKYTVNFLEAKE 239 Query: 262 GLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQA 321 G +E F+ S +HG A WF V F G S + LST+P P THW Q Sbjct: 240 GDLHRIEIP----FKFHMLHSGLVHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQV 293 Query: 322 LLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRV 355 P+ + +SG L+ ++ + + Sbjct: 294 RCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISI 327 >4IKP-A nrPDB Length = 341 Score = 341 bits (874), Expect = 3e-94, Method: Composition-based stats. Identities = 121/323 (37%), Positives = 171/323 (52%), Gaps = 15/323 (4%) Query: 38 RTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILS 97 RT+ Y++ Y +S + M+ D VRT Y+ IL+N + K VLDVG G+GILS Sbjct: 1 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS 60 Query: 98 IFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWM 157 F AQAGAR++YAVEAS + Q A +V+ N L DR+ V+PG VE V LPEQVD I+SE M Sbjct: 61 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPM 120 Query: 158 GYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQ 213 GY L +E ML S LHA+ K+LK G + P ++ +AP +D+ L + FW Q Sbjct: 121 GYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSF 179 Query: 214 HYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLEL-SRAGLEQELEAGVG 272 H GVD+S L G A + VV ++A+ ++ L ++ G +E Sbjct: 180 H-GVDLSALRGAAVDEYF--RQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIP-- 234 Query: 273 GRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVE 332 F+ S +HG A WF V F G S + LST+P P THW Q P+ + Sbjct: 235 --FKFHMLHSGLVHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAK 290 Query: 333 QDTDVSGEITLLPSRDNPRRLRV 355 +SG L+ ++ + + Sbjct: 291 AGDTLSGTCLLIANKRQSYDISI 313 >5EKU-A nrPDB Length = 390 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 77/289 (26%), Positives = 123/289 (42%), Gaps = 30/289 (10%) Query: 57 HEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA- 115 H M+ D R + Y + ++ G VL++GAG+G+LS+ A+ GA+ V AVE S Sbjct: 72 HYAMMNDEERNNFYYEVLKKHVTPETG--VLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 129 Query: 116 IWQQAREVVRFNGLEDRV---HVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLH 172 + + ARE +R N +E +V H++ ++ LPE D ++SE G +L ES L V+ Sbjct: 130 LAKLARENIRANNMEHQVKVLHMMSTELKPKHLPEPPDVLLSEIFGTMMLGESALDYVVD 189 Query: 173 ARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMG 232 R + LK ++P + PI L R+ S + M L+ + Sbjct: 190 VRNRLLKPTTKIIPQFGTQYAVPIECDALH-RISSVSGWRDLDLKHMMTLQDTVSIVFAK 248 Query: 233 HSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGR--FRCSCYGSAPMHGFAI 290 H I + ++ L+ P +EL R + R F S H Sbjct: 249 HYGIRMNSVNFRR-LSDP-----IELFRVDFSSSNRNDISRRKHFDVVAKESGTAHAMLF 302 Query: 291 WFQVTFPGGESEKPLVLSTSP------FHPATHWKQALLYLNE---PVQ 330 +++VT + V+ST P F W QAL L+ P+ Sbjct: 303 YWKVT------DDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLP 345 >4M36-A nrPDB Length = 343 Score = 250 bits (637), Expect = 9e-67, Method: Composition-based stats. Identities = 77/289 (26%), Positives = 124/289 (42%), Gaps = 30/289 (10%) Query: 57 HEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA- 115 H M+ D R + Y + ++ G VL++GAG+G+LS+ A+ GA+ V AVE S Sbjct: 37 HYAMMNDEERNNFYYEVLKKHVTPETG--VLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 94 Query: 116 IWQQAREVVRFNGLEDRV---HVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLH 172 + + ARE +R N +E +V H++ +++ LPE D ++SE G +L ES L V+ Sbjct: 95 LAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVD 154 Query: 173 ARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMG 232 R + LK ++P + PI L R+ S + M L+ + Sbjct: 155 VRNRLLKPTTKIIPQFGTQYAVPIECDALH-RISSVSGWRDLDLKHMMTLQDTVSIVFAK 213 Query: 233 HSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGR--FRCSCYGSAPMHGFAI 290 H I + ++ L+ P +EL R + R F S H Sbjct: 214 HYGIRMNSVNFRR-LSDP-----IELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLF 267 Query: 291 WFQVTFPGGESEKPLVLSTSP------FHPATHWKQALLYLNE---PVQ 330 +++VT + V+ST P F W QAL L+ P+ Sbjct: 268 YWKVT------DDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLP 310 >4LWO-B nrPDB Length = 368 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 107/367 (29%), Positives = 162/367 (44%), Gaps = 69/367 (18%) Query: 46 LYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGA 105 YYE YSD++VH M+ D R YR I ++ A++ GK V+DVG+GTGILS++ A+AGA Sbjct: 19 QYYESYSDLAVHRLMLEDAQRMSFYRKSIEQS-ASIEGKVVVDVGSGTGILSMWAARAGA 77 Query: 106 RRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP---------------EQVD 150 + V+++EAS++ + VV N L ++ VL VE + V Sbjct: 78 KHVFSIEASSLSEFQIGVVEDNDLSTKITVLGDTVENIIAGGVANFVNRHKAKLGKCGVA 137 Query: 151 AIVSEWMGYGLLHESMLSSVLHARTKWLKEGG--------LLLPASAELFIAPISDQ--M 200 ++SEWMG+ L HE ML SV+ AR + ++P A +F+API+ + Sbjct: 138 VLLSEWMGFYLFHEGMLPSVIRARNFFQDVNAALGVLQPIEMIPERATVFVAPITCKPYY 197 Query: 201 LEWRLGFWSQVKQHYGVDMS----------------CLEGFATRCLMGHSEIVVQ-GLSG 243 ++ FW V G+D S +E CL+ +++ LS Sbjct: 198 VQRYKNFWRDVD---GLDFSRYGRIEYEVYLEQASPLVECLPPLCLLHEGLSLIELNLST 254 Query: 244 --EDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGES 301 E+VL +L + Q+ G R S + GF +WF V++ Sbjct: 255 VQEEVLTSLHNTVHFDLKESAEFQQHAREAGSEGRVS------VDGFTVWFDVSYGAHT- 307 Query: 302 EKPLVLSTSPFHPATHWKQALLYLNEP--------VQVEQDTDVSGEITLLPSRDNPRRL 353 LSTSP P+THWKQ + L VE + E+ + S R Sbjct: 308 -----LSTSPRSPSTHWKQTTILLPREARNEELVSFPVEGGE-LGVEMHISASDKTLRFY 361 Query: 354 RVLLRYK 360 + L K Sbjct: 362 TIELELK 368 >6OGN-A nrPDB Length = 692 Score = 205 bits (521), Expect = 3e-53, Method: Composition-based stats. Identities = 68/330 (20%), Positives = 119/330 (36%), Gaps = 30/330 (9%) Query: 30 EAALERPRRTKRERDQLYYECYSDV--SVHEEMIADRVRTDAYRLGILRNWAALRGK--- 84 A + + +Y+ + ++ S + +M+ D+ R Y GI + ++ + Sbjct: 6 GRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQK 65 Query: 85 -TVLDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPVET 142 VLD+G GTG+LS+ AGA YA+E + + A ++V NG D++ V+ Sbjct: 66 ALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKVINKHSTE 125 Query: 143 V------ELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPI 196 V +LP + + +++E L+ E L S HA ++E +P A ++ + Sbjct: 126 VTVGPDGDLPCRANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLV 185 Query: 197 SD-QMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQ 255 +M W F +V+ G + RC V + V P F Sbjct: 186 ESRRMWSWNKLFPVRVRTSLGEQVIVPPSELERC---PGAPSVCDIQLNQV--SPADFTV 240 Query: 256 LELSRAGLEQELEAGVGGRFRCSCYG-----SAPMHGFAIWFQVTFPG----GESEKPLV 306 L + V C S W+ + + P Sbjct: 241 LSDVLPMFSVDFSKQVSSSAACHSRQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFW 300 Query: 307 LSTSPFHPA--THWKQALLYLNEPVQVEQD 334 T P HW Q + +L + V Q Sbjct: 301 AQTDPQELQWRDHWMQCVYFLPQEEPVVQG 330 >3X0D-A nrPDB Length = 655 Score = 171 bits (432), Expect = 6e-43, Method: Composition-based stats. Identities = 68/329 (20%), Positives = 127/329 (38%), Gaps = 35/329 (10%) Query: 59 EMIADRVRTDAYRLGILRNWAALR-----GKT-VLDVGAGTGILSIFCAQAGARRVYAVE 112 +MI D R D + G+ A + GK VLD+G GTG+LS+ A+ GA +V A+E Sbjct: 43 DMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALE 102 Query: 113 A-SAIWQQAREVVRFNGLEDRVHVLPGPVETVELP--EQVDAIVSEWMGYGLLHESMLSS 169 + AR + + D++ V+ V + D IV+E L+ E L + Sbjct: 103 VFKPMGDCARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRT 162 Query: 170 VLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCL-EGFATR 228 A + K G ++P++ ++I P+ +L+ F + + D L T Sbjct: 163 FKEALERLAKPGCRVVPSTGNVYIVPVESHLLKM---FNDIPRLNGEKDEEPLGRCSGTA 219 Query: 229 CLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRF--RCSCYGSAPMH 286 + ++ + L+ P + + E E + F + S + Sbjct: 220 AVFDVQLSEMKTHEFRE-LSEPIVAFKFD-----FEHEEKIIFDESFVREAVAHSSGTID 273 Query: 287 GFAIWFQVTFPGGESE----KPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEIT 342 +W+ + + P + + + HW QA+ YL E +VE + EI Sbjct: 274 ALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTF--EIV 331 Query: 343 LLPSRDNPRRLRVLLRYKVGDQEEKTKDF 371 N + + ++K++ + Sbjct: 332 C-----NHDEFSL---WFSNVGKDKSRSY 352 >4G56-A nrPDB Length = 657 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 61/295 (20%), Positives = 106/295 (35%), Gaps = 44/295 (14%) Query: 62 ADRVRTDAYRLGILR---NWAALRGK-----TVLDVGAGTGIL---SIFCAQAGARR--V 108 D V+ Y+ + + + K ++ +GAG G L S+ A+ R+ V Sbjct: 349 KDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKV 408 Query: 109 YAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLS 168 YAVE + E R+ +V V+ G + + PE+ D IVSE +G + Sbjct: 409 YAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLG-SFGDNELSP 467 Query: 169 SVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATR 228 L +LK+ G+ +P ++APIS L ++V+ D Sbjct: 468 ECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLY------NEVRACREKD-----RDPEA 516 Query: 229 CLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYG---SAPM 285 + + L+ P L + + R+ C Y + + Sbjct: 517 QFEMPYVVRLHNFHQ---LSDP-----LPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVL 568 Query: 286 HGFAIWFQVTFPGGESEKPLVLSTSPFHPAT---HWKQALLYLNEPVQVEQDTDV 337 HGFA +F K + LS P + W L + +P+ + + V Sbjct: 569 HGFAGYFNTVL-----YKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTV 618 >5FA5-A nrPDB Length = 650 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 53/294 (18%), Positives = 97/294 (32%), Gaps = 42/294 (14%) Query: 62 ADRVRTDAYRLGILRN-----WAALRG---KTVLDVGAGTGIL---SIFCAQAGARRV-- 108 D ++ Y+ I + + + ++ +GAG G L S+ A+ RR+ Sbjct: 342 KDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKL 401 Query: 109 YAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLS 168 YAVE + E +F +V V+ + PE+ D IVSE +G + Sbjct: 402 YAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLG-SFADNELSP 460 Query: 169 SVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWS--QVKQHYGVDMSCLEGFA 226 L +LK+ G+ +P F+APIS L + +M + Sbjct: 461 ECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLH 520 Query: 227 TRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMH 286 + + + ++ + +H Sbjct: 521 NFHQLSAPQPCFTFSHPNR------------------DPMIDNNRYCTLEFPVEVNTVLH 562 Query: 287 GFAIWFQVTFPGGESEKPLVLSTSP--FHPAT-HWKQALLYLNEPVQVEQDTDV 337 GFA +F+ + + LS P P W L + +P+ V + + Sbjct: 563 GFAGYFETVL-----YQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTI 611 >4QNV-A nrPDB Length = 323 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 3/135 (2%) Query: 52 SDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAV 111 S++ I R+D +L + + L G+T+LDVG G+G AGA + Sbjct: 92 GPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGI 151 Query: 112 EASAIWQQAREVVR-FNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSV 170 + + ++ E VR G + R H+LP +E + + D + S MG S L + Sbjct: 152 DPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFS--MGVLYHRRSPLEHL 209 Query: 171 LHARTKWLKEGGLLL 185 + + + EG L+L Sbjct: 210 WQLKDQLVNEGELVL 224 >4P7C-A nrPDB Length = 322 Score = 90.6 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 37/160 (23%), Positives = 63/160 (39%), Gaps = 13/160 (8%) Query: 54 VSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEA 113 VH I R+D + + L+GK VLDVG G G AGA V V+ Sbjct: 97 FGVH---IDTEWRSDWKWSRVSPHL-DLKGKRVLDVGCGNGYYQWRMLGAGADSVIGVDP 152 Query: 114 SAIWQQAREVVRFNGLEDRVHVLPGPVETVEL-PEQVDAIVSEWMGYGLLHESMLSSVLH 172 + ++ + ++ + LP +E + E D + S MG +S + +L Sbjct: 153 NWLFFCQFQAMQRYLPDLPAWHLPFALEDLPANLEGFDTVFS--MGVLYHRKSPIDHLLA 210 Query: 173 ARTKWLKEGG-----LLLPASAELFIAPISDQMLEWRLGF 207 + +K G L++P + P D+ + R + Sbjct: 211 LKDCLVKGGELVMETLVIPGDVHQVLVP-EDRYAQMRNVW 249 >3UA4-A nrPDB Length = 745 Score = 87.1 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 49/328 (14%), Positives = 103/328 (31%), Gaps = 45/328 (13%) Query: 53 DVSVHEEMIADRVRTDAYRLGILRNWAAL-----RGKTVLDVGAGTGIL----------- 96 D V+ D+++ D Y ++ L + + +G G G + Sbjct: 375 DSGVYNTFEQDQIKYDVYGEAVVGALKDLGADGRKTVVIYLLGGGRGPIGTKILKSEREY 434 Query: 97 --SIFCAQAGAR-RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP------E 147 + Q + ++Y VE + + + + RV ++ + ++ E Sbjct: 435 NNTFRQGQESLKVKLYIVEKNPNAIVTLKYMNVRTWKRRVTIIESDMRSLPGIAKDRGFE 494 Query: 148 QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLG- 206 Q D IVSE +G + L T +LK + +P ++ PI + + Sbjct: 495 QPDIIVSELLG-SFGDNELSPECLDGVTGFLKPTTISIPQKYTSYVKPIMSTHIHQTIKA 553 Query: 207 ----FWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSG------EDVLARPQRFAQL 256 + S+ +G L+ V + + + + Sbjct: 554 QSIPYLSRAIPSHGRGEPELDEDEMWIQKYPQGHVRNNMDQIYVVYLSKYIPLAETTKPV 613 Query: 257 ELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPA- 315 +A + GFA +F + K ++LS P Sbjct: 614 FTFEHPNFMNSSNERSDSIEFVMDRNADLMGFAGYFDLQL-----YKTVMLSIEPSTHTP 668 Query: 316 --THWKQALLYLNEPVQVEQDTDVSGEI 341 W A++ L + ++V + +S +I Sbjct: 669 GMVSWFPAVIPLRDQLRVGEGDRISLKI 696 >5Z9O-A nrPDB Length = 399 Score = 51.7 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 74 ILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVR----FNGL 129 IL +GKT+LD+G G G L + A+ +V V + ++ ++V+ GL Sbjct: 157 ILNKLHPEKGKTLLDIGCGWGTLMLTAAKEYGLKVTGV---TLSEEQYKLVQKKIYDEGL 213 Query: 130 EDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 ED V + +Q D + S M + E++ K+LK G+ L Sbjct: 214 EDVAEVKLEDYRELG-DQQWDYVTSVGMFEHVGSENLGEYFKDVA-KYLKNDGVAL 267 >1L3B-A nrPDB Length = 192 Score = 50.9 bits (120), Expect = 9e-07, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 7/105 (6%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQARE-VVRFNGLEDRVHVLPGPV 140 + +DVG GTG +++ A RRVYA++ + E ++ +GL D V ++ G Sbjct: 33 KNDVAVDVGCGTGGVTLELAG-RVRRVYAIDRNPEAISTTEMNLQRHGLGDNVTLMEGDA 91 Query: 141 ETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 L + D ++ G G L +L LK GG ++ Sbjct: 92 PE-ALCKIPDIDIAVVGGSG----GELQEILRIIKDKLKPGGRII 131 >2AS0-A nrPDB Length = 396 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 14/124 (11%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW-QQAREVVRFNGLEDRVHVLPG--- 138 G VLDV TG +I A AGA V ++ S + A+E + NG+EDR+ + G Sbjct: 218 GDRVLDVFTYTGGFAIHAAIAGADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSAF 277 Query: 139 -PVETV-ELPEQVDAIVSEWMGYGLLHESMLSSVLHAR-------TKWLKEGGLLLPASA 189 +E + + E+ D +V + + HE L + L A +K+GG+L+ S Sbjct: 278 EEMEKLQKKGEKFDIVVLDP-PAFVQHEKDLKAGLRAYFNVNFAGLNLVKDGGILVTCSC 336 Query: 190 ELFI 193 + Sbjct: 337 SQHV 340 >3SVZ-A nrPDB Length = 263 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 36/188 (19%), Positives = 69/188 (36%), Gaps = 17/188 (9%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASA--IWQQAREVVRFNGLEDRVHVLPGPV 140 + D+G GTG ++F A ++ ++ I V+ N DRV + G + Sbjct: 53 DAKIADIGCGTGGQTLFLADYVKGQITGIDLFPDFIEIFNENAVKAN-CADRVKGITGSM 111 Query: 141 ETVE-LPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQ 199 + + E++D I SE Y + E ++ +K+LK+GG + + A F + + Sbjct: 112 DNLPFQNEELDLIWSEGAIYNIGFERGMNEW----SKYLKKGGFIAVSEASWF----TSE 163 Query: 200 MLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELS 259 FW ++S + + + E+ FA + Sbjct: 164 RPAEIEDFWMDAYP----EISVIPTCIDKMERAGYTPTAHFILPENCWTE-HYFAPQDEV 218 Query: 260 RAGLEQEL 267 R +E Sbjct: 219 RETFMKEH 226 >1WY7-A nrPDB Length = 207 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 77 NWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVL 136 + + GK V D+GAGTG+LS GA+ V VE + + + V Sbjct: 44 SLGDIEGKVVADLGAGTGVLSYGALLLGAKEVICVEVDKEAVDVL-IENLGEFKGKFKVF 102 Query: 137 PGPVETVELPEQVDAIV 153 G V +VD ++ Sbjct: 103 IGDVSEFN--SRVDIVI 117 >3DLC-A nrPDB Length = 219 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 5/111 (4%) Query: 77 NWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHV 135 N + T +D+G+G G LSI A+ + A++ S + + A + + L DR+ + Sbjct: 38 NRFGITAGTCIDIGSGPGALSIALAKQSDFSIRALDFSKHMNEIALKNIADANLNDRIQI 97 Query: 136 LPGPVETVELPEQ-VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + G V + + + D IVS G E + ++ + LK GG Sbjct: 98 VQGDVHNIPIEDNYADLIVSR--GSVFFWEDVATAFREIY-RILKSGGKTY 145 >3D2L-A nrPDB Length = 243 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 13/140 (9%) Query: 50 CYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVY 109 V++E++ D + + + GK + D+G GTG ++ A Y Sbjct: 4 YEQFAYVYDELMQDVPYPEWVAWVLEQ---VEPGKRIADIGCGTGTATLLLADH-----Y 55 Query: 110 AVEASAIWQQAREVVRFNGLEDRVHV--LPGPVETVELPEQVD--AIVSEWMGYGLLHES 165 V + ++ E+ + +E HV + +ELPE VD I+ + + Y L E+ Sbjct: 56 EVTGVDLSEEMLEIAQEKAMETNRHVDFWVQDMRELELPEPVDAITILCDSLNY-LQTEA 114 Query: 166 MLSSVLHARTKWLKEGGLLL 185 + + + L +GG LL Sbjct: 115 DVKQTFDSAARLLTDGGKLL 134 >4KRG-A nrPDB Length = 466 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 8/149 (5%) Query: 40 KRERDQLYYECYSDVSVHEEMIADRVRTD---AYRLGILRNWAALRGKTVLDVGAGTGIL 96 +R+ + +++ YSD M+ ++ D + R IL + L K V+D+GAG G Sbjct: 12 RRDSFKTFWDKYSDKPDTNSMMLNQTAQDLEASDRADILSSLPHLTNKDVVDIGAGIGRF 71 Query: 97 SIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQ-VDAIVSE 155 + A+ AR V + + I + N + G +++ E+ VD + + Sbjct: 72 TTVLAET-ARWVLSTDF--IESFIEKNQERNAHMGNISYQIGDAVHLQMDEKSVDLVFTN 128 Query: 156 WMGYGLLHESMLSSVLHARTKWLKEGGLL 184 W+ L ++ +L+A +WL+ G + Sbjct: 129 WLMMYLSDREVIEFLLNAM-RWLRADGYI 156 >3EGE-A nrPDB Length = 261 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 11/115 (9%) Query: 72 LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLED 131 I+ +G + D+GAGTG S+ A G VYAVE S + +Q V Sbjct: 24 NAIINLLNLPKGSVIADIGAGTGGYSVALANQGL-FVYAVEPSIVMRQQAVVHPQVEW-- 80 Query: 132 RVHVLPGPVETVELPEQ-VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 G E + LP++ VD ++S + H S L + +++G ++L Sbjct: 81 ----FTGYAENLALPDKSVDGVISIL---AIHHFSHLEKSFQEMQRIIRDGTIVL 128 >5WP5-A nrPDB Length = 491 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 10/163 (6%) Query: 36 PRRTKRERDQLYYECYSDVSVHEEMIADRVRTD---AYRLGILRNWAALRGKTVLDVGAG 92 P + +R+ + Y+ +S E M+ D +D R +L GK+VL++GAG Sbjct: 4 PYKEERDIQKSYWMEHSSDLTVEAMMLDSKASDLDKEERPEVLSLIPPYEGKSVLELGAG 63 Query: 93 TGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQ---V 149 G + AQ A V A++ Q E V NG + + V + +L + + Sbjct: 64 IGRFTGELAQ-KAGEVIALDFIESAIQKNESV--NGHYKNIKFMCADVTSPDLKIKDGSI 120 Query: 150 DAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELF 192 D I S W+ L + + + W+K GG + + Sbjct: 121 DLIFSNWL-LMYLSDKEVELMAERMIGWVKPGGYIFFRESCFH 162 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 57/163 (34%), Gaps = 9/163 (5%) Query: 32 ALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYR--LGILRNWAALRGKTVLDV 89 ++E + +R D + Y+ + V T + + G+ VLDV Sbjct: 230 SVENDKDFQRFLDNVQYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQKVLDV 289 Query: 90 GAGTGILSIFCAQAGARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGPVETVELPE- 147 G G G + A+ V ++ S + A E R GL+ V T P+ Sbjct: 290 GCGIGGGDFYMAENFDVHVVGIDLSVNMISFALE--RAIGLKCSVEFEVADCTTKTYPDN 347 Query: 148 QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAE 190 D I S L + ++ KWLK GG +L Sbjct: 348 SFDVIYSR--DTILHIQDK-PALFRTFFKWLKPGGKVLITDYC 387 >3A26-A nrPDB Length = 301 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 57/162 (35%), Gaps = 13/162 (8%) Query: 71 RLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGL 129 + + A + V+D+ AG G LS+ A G +V A+E ++ E + N + Sbjct: 137 KERVRMAKVAKPDELVVDMFAGIGHLSLPIAVYGKAKVIAIEKDPYTFKFLVENIHLNKV 196 Query: 130 EDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASA 189 EDR+ D I+ MGY + + L + + G ++ Sbjct: 197 EDRMSAYNMDNRDFPGENIADRIL---MGYVVRTHEFIPKALS-----IAKDGAIIHYHN 248 Query: 190 ELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLM 231 P M + ++ + YG D+ L + Sbjct: 249 T---VP-EKLMPREPFETFKRITKEYGYDVEKLNELKIKRYA 286 >5JE5-A nrPDB Length = 247 Score = 44.4 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 48/139 (34%), Gaps = 5/139 (3%) Query: 48 YECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARR 107 Y+ + E+ + I + GK+VLD+ G G + GA + Sbjct: 9 YDSIG--GLFEDFTQSAAQRAIEVRTIFHMIGDVSGKSVLDLACGFGFFGREIYRRGAAK 66 Query: 108 VYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESM 166 V V+ S + + ARE D + V +E Q D + + W+ Sbjct: 67 VVGVDISEKMIELARE--ESRKYGDPLEFHVRDVANMEPLGQFDLVNAAWLFNYADSVEN 124 Query: 167 LSSVLHARTKWLKEGGLLL 185 L + LK G L+ Sbjct: 125 LRKMFKVVRASLKPDGKLV 143 >1XDU-A nrPDB Length = 374 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 40/153 (26%), Positives = 60/153 (39%), Gaps = 13/153 (8%) Query: 35 RPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAY-RLGILRNWAALRGKTVLDVGAGT 93 RP D + + + +E +A DAY + VLDVG G Sbjct: 143 RPFWEDLSADVALADSFDALMSCDEDLAYEAPADAYDWSAVRH---------VLDVGGGN 193 Query: 94 G-ILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAI 152 G +L+ +A R VE + ++AR GL DRV V G LP D + Sbjct: 194 GGMLAAIALRAPHLRGTLVELAGPAERARRRFADAGLADRVTVAEGDFFK-PLPVTADVV 252 Query: 153 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + ++ E L ++L + L+ GG LL Sbjct: 253 LLSFVLLNWSDEDAL-TILRGCVRALEPGGRLL 284 >4LG1-A nrPDB Length = 224 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 79 AALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGL----EDRVH 134 AL ++VL++G+GTG + + A GA V + + + + N + Sbjct: 59 HALSRRSVLELGSGTGAVGLMAATLGAD-VVVTDLEELQDLLKMNINMNKHLVTGSVQAK 117 Query: 135 VLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVL 171 VL E P D I+ M + +E L +L Sbjct: 118 VLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLL 151 >2ZZN-A nrPDB Length = 336 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 5/81 (6%) Query: 65 VRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW-QQAREV 123 R R I++ + V+D+ AG G SI C A+++YA++ + + ++ Sbjct: 180 PRLGGERARIMKKVSL--NDVVVDMFAGVGPFSIAC--KNAKKIYAIDINPHAIELLKKN 235 Query: 124 VRFNGLEDRVHVLPGPVETVE 144 ++ N LE ++ + V V+ Sbjct: 236 IKLNKLEHKIIPILSDVREVD 256 >4KDR-A nrPDB Length = 223 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 11/107 (10%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHV--LPGPV 140 GK VLDVG G GIL+ A+ GA V ++ + + +V + + LE + V + V Sbjct: 63 GKKVLDVGCGGGILAESMAREGAT-VTGLD---MGFEPLQVAKLHALESGIQVDYVQETV 118 Query: 141 ETVELPE--QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 E Q D + M L H SV+ A + +K GG + Sbjct: 119 EEHAAKHAGQYDVVTCMEM---LEHVPDPQSVVRACAQLVKPGGDVF 162 >4PNE-A nrPDB Length = 302 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 30/104 (28%), Positives = 45/104 (43%), Gaps = 11/104 (10%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAI-----WQQAREVVRFNGLEDRVHVLPGPV 140 +LDVG GTG ++ A+ A ++ + S + ARE GL RV V Sbjct: 96 LLDVGCGTGQPALRVARDNAIQITGITVSQVQVAIAADCARE----RGLSHRVDF--SCV 149 Query: 141 ETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLL 184 + + LP +A + W LL S + + LK GG+L Sbjct: 150 DAMSLPYPDNAFDAAWAMQSLLEMSEPDRAIREILRVLKPGGIL 193 >4KDC-A nrPDB Length = 246 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 11/107 (10%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHV--LPGPV 140 GK VLDVG G GIL+ A+ GA V ++ + + +V + + LE + V + V Sbjct: 63 GKKVLDVGCGGGILAESMAREGAT-VTGLD---MGFEPLQVAKLHALESGIQVDYVQETV 118 Query: 141 ETVELPE--QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 E Q D + M L H SV+ A + +K GG + Sbjct: 119 EEHAAKHAGQYDVVTCMEM---LEHVPDPQSVVRACAQLVKPGGDVF 162 >3LPM-A nrPDB Length = 259 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLP--- 137 +GK + D+ +G GI+ + + ++ VE + A+ V +N LED++ ++ Sbjct: 50 KGKII-DLCSGNGIIPLLLSTRTKAKIVGVEIQERLADMAKRSVAYNQLEDQIEIIEYDL 108 Query: 138 GPVETVELPEQVDAI 152 + + E+ D + Sbjct: 109 KKITDLIPKERADIV 123 >6BQC-A nrPDB Length = 383 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 56/172 (32%), Gaps = 16/172 (9%) Query: 69 AYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNG 128 A I G VLD+G G G L+ + A V V SA QQ R G Sbjct: 155 AKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISA-EQQKMAQERCEG 213 Query: 129 LEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPAS 188 L+ V +L + +Q D IVS M + + + + LK G+ L + Sbjct: 214 LD--VTILLQDYRDLN--DQFDRIVSVGM-FEHVGPKNYDTYFAVVDRNLKPEGIFLLHT 268 Query: 189 AELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG 240 I + + + W Y CL V++ Sbjct: 269 -------IGSKKTDLNVDPWIN---KYIFPNGCLPSVRQIAQSSEPHFVMED 310 >3BKW-A nrPDB Length = 243 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 55/151 (36%), Gaps = 12/151 (7%) Query: 47 YYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR 106 ++ YS + E + A + + G ++D+G G G + + GA Sbjct: 12 FFAGYSQLGRSIEGLDGA----AEWPALRAMLPEVGGLRIVDLGCGFGWFCRWAHEHGAS 67 Query: 107 RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPE-QVDAIVSEWMGYGLLHES 165 V ++ + ++ R G + + ++ + LP+ D S L + Sbjct: 68 YVLGLD---LSEKMLARARAAGPDTGITYERADLDKLHLPQDSFDLAYSSL---ALHYVE 121 Query: 166 MLSSVLHARTKWLKEGG-LLLPASAELFIAP 195 ++ + + L GG + +++AP Sbjct: 122 DVARLFRTVHQALSPGGHFVFSTEHPIYMAP 152 >1RI1-A nrPDB Length = 298 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 40/233 (17%), Positives = 79/233 (33%), Gaps = 31/233 (13%) Query: 16 EGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRT-DAYRLGI 74 + EG +EE + ER R +++ + +R + + Sbjct: 14 QAMEGKKEEIREHYNSIRERGRESRQRSKTI-----------------NIRNANNFIKAC 56 Query: 75 LRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVH 134 L RG +VLD+G G G + +AG Y V+ + + VR ++ R Sbjct: 57 LIRLYTKRGDSVLDLGCGKGGDLLKYERAGIGEYYGVDIAEVS-INDARVRARNMKRRFK 115 Query: 135 VL----PGPVETVELPEQVDAIVSEW-MGYGLLHESMLSSVLHARTKWLKEGGLLLPASA 189 V ++L ++ D I S++ Y L + L+ GG + Sbjct: 116 VFFRAQDSYGRHMDLGKEFDVISSQFSFHYAFSTSESLDIAQRNIARHLRPGGYFI---- 171 Query: 190 ELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLS 242 P D +LE Y +++ +E + + ++ ++ Sbjct: 172 --MTVPSRDVILERYKQ-GRMSNDFYKIELEKMEDVPMESVREYRFTLLDSVN 221 >5YAC-A nrPDB Length = 346 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 69/201 (34%), Gaps = 34/201 (16%) Query: 34 ERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGT 93 E R K + ++Y+ R R+ + A G+ V D+ AG Sbjct: 167 ENGIRLKLDVAKVYFS---------------PRLATERMRVF--KMAQEGEVVFDMFAGV 209 Query: 94 GILSIFCAQAGARRVYAVEASAIW-QQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAI 152 G SI A+ A V+A + + + E ++ N + + V +L G +E+ + D I Sbjct: 210 GPFSILLAK-KAELVFACDINPWAIKYLEENIKLNKVNNVVPIL-GDSREIEV--KADRI 265 Query: 153 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVK 212 + M L + + +GG++ + W L ++ Sbjct: 266 I---MNLPKYAHEFLEHAISC----INDGGVI-----HYYGFGPEGDPYGWHLERIRELA 313 Query: 213 QHYGVDMSCLEGFATRCLMGH 233 +GV + L R Sbjct: 314 NKFGVKVEVLGKRVIRNYAPR 334 >5WP4-A nrPDB Length = 491 Score = 41.7 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 7/110 (6%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGPVE 141 G+ VLDVG G G + A+ V ++ S + A E R GL V Sbjct: 283 GQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALE--RAIGLSCSVEFEVADCT 340 Query: 142 TVELPE-QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAE 190 T P+ D I S L + ++ KWLK GG +L + Sbjct: 341 TKHYPDNSFDVIYSR--DTILHIQDK-PALFRTFFKWLKPGGKVLISDYC 387 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%) Query: 38 RTKRERDQLYYECYSDVSVHEEMIADRVRTD---AYRLGILRNWAALRGKTVLDVGAGTG 94 +R+ + Y+ +S E M+ D +D R +L GK+VL++GAG G Sbjct: 6 EEERDIQKNYWIEHSADLTVEAMMLDSRASDLDKEERPEVLSLLPPYEGKSVLELGAGIG 65 Query: 95 ILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP---EQVDA 151 + AQ A + A++ + E + NG V + V + +L +D Sbjct: 66 RFTGELAQ-KAGELIALDFIDNVIKKNESI--NGHYKNVKFMCADVTSPDLKITDGSLDL 122 Query: 152 IVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELF 192 I S W+ L + + + W+K GG + + Sbjct: 123 IFSNWL-LMYLSDKEVELLAERMVGWIKVGGYIFFRESCFH 162 >2XVM-A nrPDB Length = 199 Score = 41.7 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 33/167 (19%), Positives = 59/167 (35%), Gaps = 23/167 (13%) Query: 43 RDQLYY-ECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCA 101 RD+ Y+ + Y H E +L ++ LD+G G G S++ A Sbjct: 6 RDENYFTDKYELTRTHSE--------------VLEAVKVVKPGKTLDLGCGNGRNSLYLA 51 Query: 102 QAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGL 161 G V A + +A+ E ++ D +H + + Q D I+S + Sbjct: 52 ANGYD-VDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILSTVV-LMF 109 Query: 162 LHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFW 208 L + ++ + K GG L +A + +GF Sbjct: 110 LEAKTIPGLIANMQRCTKPGG------YNLIVAAMDTADYPCTVGFP 150 >1KP9-A nrPDB Length = 287 Score = 41.7 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 38/109 (34%), Gaps = 4/109 (3%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAI-WQQAREVVRFNGLEDRVHVLPGPVE 141 G T+LDVG G G + + V + S +++V + VL E Sbjct: 65 GMTLLDVGCGWGATMMRAVEKYDVNVVGLTLSKNQANHVQQLVANSENLRSKRVLLAGWE 124 Query: 142 TVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAE 190 + E VD IVS + + + L G++L + Sbjct: 125 QFD--EPVDRIVS-IGAFEHFGHERYDAFFSLAHRLLPADGVMLLHTIT 170 >5FAD-A nrPDB Length = 161 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 43/112 (38%), Gaps = 9/112 (8%) Query: 82 RGKTVLDVGAGTGILSIFCAQA-GARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGP 139 + V D+G G G + I A+ ++ VE + ++A + NG+ R ++ G Sbjct: 28 QDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTGRASIVKGN 87 Query: 140 VETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAEL 191 V++ E L ++ + K LK G ++ E+ Sbjct: 88 FFEVDISEATVV-------TMFLLTNVNEMLKPKLEKELKPGTRVVSHEFEI 132 >5BP9-A nrPDB Length = 281 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 12/110 (10%) Query: 85 TVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLED--RVHVLPGPVET 142 T+LDVGAG+G ++ Q + V A++ S + EV++ G++D +V++ Sbjct: 104 TILDVGAGSGCHAL-ALQESGKEVSAIDISPLS---VEVMKLRGVKDARQVNLFDER--- 156 Query: 143 VELPEQVDAIVSEWMGYGLLHE-SMLSSVLHARTKWLKEGGLLLPASAEL 191 D I+ G G++ + + L+ G +L S++L Sbjct: 157 --FAATFDTILMLMNGSGIIGRLENMPLFFRKMKQLLRPDGCILMDSSDL 204 >5H02-A nrPDB Length = 283 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 41/172 (23%), Positives = 63/172 (36%), Gaps = 7/172 (4%) Query: 41 RERDQLYYECYSDVSVHEEMIAD-RVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIF 99 RE D E S + + D R ++ I+ K VLDV GTG S+ Sbjct: 37 RESDGYTNEYVSGFVDKWDELIDWESRAESEGDTIINILKERGVKKVLDVATGTGFNSVR 96 Query: 100 CAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMG- 158 QAG V A ++ + +A + R +G R ++ ++ DAIV +G Sbjct: 97 LLQAGFDVVSADGSAEMLVKAFDNARDHGYLMRTVQADWRWMNKDIHDKFDAIVC--LGN 154 Query: 159 --YGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFW 208 L E L LK G+LL + A + D ++ Sbjct: 155 SFTHLFDEGDRRKALAEFYALLKHDGVLLLDQRN-YDAILDDGYSSKHAHYY 205 >4QPN-A nrPDB Length = 227 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 9/110 (8%) Query: 80 ALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQARE-VVRFN---GLEDRVHV 135 RGK V+++GAGTGI+ I A G + + + + V+ N G + +V Sbjct: 74 DFRGKKVIELGAGTGIVGILAALQGGD--VTITDLPLALEQIQGNVQANVPAGGQAQVRA 131 Query: 136 LPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 L ++ P D ++ + Y E +L + G + Sbjct: 132 LSWGIDHHVFPANYDLVLGADIVYL---EPTFPLLLGTLQHLCRPHGTIY 178 >3CCF-A nrPDB Length = 279 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 49/120 (40%), Gaps = 9/120 (7%) Query: 70 YRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGL 129 Y +L+ G+ +LD+G GTG L+ AQ+GA + A+ + ++AR+ Sbjct: 45 YGEDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVLGTDNAATMIEKARQNYPHLHF 104 Query: 130 EDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASA 189 + + + +DA+ S M L + + + + LK GG + Sbjct: 105 D------VADARNFRVDKPLDAVFSNAM---LHWVKEPEAAIASIHQALKSGGRFVAEFG 155 >4O29-A nrPDB Length = 208 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 17/109 (15%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARR--VYAVE-ASAIWQQAREVVRFNGLEDRVHVLPGP 139 G +L+VG G+G + CA+A ++ +Y +E + A + + G V V G Sbjct: 76 GMKILEVGTGSGYHAAVCAEAIEKKGRIYTIEIVKELAVFAAQNLERLGYWGVVEVYHGD 135 Query: 140 VE---TVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + P DAI+ + + A + LK+GG+++ Sbjct: 136 GKKGLEKHAP--FDAIIVT---------AAADVIPPALIRQLKDGGVMV 173 >3GU3-A nrPDB Length = 284 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 49/128 (38%), Gaps = 9/128 (7%) Query: 62 ADRVRTDAYRLGILRNWAALRGKT-VLDVGAGTGILS--IFCAQAGARRVYAVEASA-IW 117 D D Y ++ + ++D G G G L + + +++ + Sbjct: 1 RDLYYNDDYVSFLVNTVWKITKPVHIVDYGCGYGYLGLVLMPLLPEGSKYTGIDSGETLL 60 Query: 118 QQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKW 177 +ARE+ R + L G +EL ++ D + LLH + ++L Sbjct: 61 AEARELFRLLPYDS--EFLEGDATEIELNDKYDIAICHAF---LLHMTTPETMLQKMIHS 115 Query: 178 LKEGGLLL 185 +K+GG ++ Sbjct: 116 VKKGGKII 123 >5GM1-A nrPDB Length = 297 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 21/48 (43%) Query: 68 DAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA 115 D Y ++ G+ +LD+G GTG ++ A+ V V S Sbjct: 63 DRYTDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVSK 110 >3CJR-A nrPDB Length = 254 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 10/109 (9%) Query: 78 WAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQ-QAREVVRFNGLEDRVHVL 136 G VLD+G G+G+L+I + G + V+ + QA + NG+ R L Sbjct: 116 RHLRPGDKVLDLGTGSGVLAIAAEKLGGK-ALGVDIDPMVLPQAEANAKRNGVRPR--FL 172 Query: 137 PGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 G +E D +V+ Y LH ++ A L GG L Sbjct: 173 EGSLEAALPFGPFDLLVANL--YAELHAALAPRYREA----LVPGGRAL 215 >4FS8-A nrPDB Length = 383 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 41/164 (25%), Positives = 63/164 (38%), Gaps = 31/164 (18%) Query: 61 IADRVRTDAYRLG-ILRNWAALRGKTVLDVGAGTGILSIFCAQA-GAR-RVYAVEASAI- 116 IAD V Y G L +L G TVLD+G GTG ++ G +V V+ Sbjct: 61 IADEVLEKFYGCGSTLPADGSLEGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQ 120 Query: 117 WQQAREVVRF-------NGLEDRVHVLPGPVETVELPEQ-------VDAIVSEWMGYGLL 162 + AR+ V + + V L G +E + E VD ++S + Sbjct: 121 LEVARKYVEYHAEKFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCVCNLST 180 Query: 163 HESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLG 206 ++ L +H + L++GG L SD + RL Sbjct: 181 NKLALFKEIH---RVLRDGGELY----------FSDVYADRRLS 211 >6GKZ-A nrPDB Length = 351 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 15/137 (10%) Query: 83 GKTVLDVGAGTGILSIFCAQAGAR-RVYAV--EASAIWQQAREVVRFNGLEDRVHVLPGP 139 G++VLD+G G G L++ AQ RV AV S E R N L V + Sbjct: 124 GQSVLDLGCGQGALTLHVAQKYKNCRVTAVTNSVSQKEYIEEESRRRNLLNVEVKL--AD 181 Query: 140 VETVELPEQVD-AIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAE-----LFI 193 + T E+ E D +V E + +E +L + ++W+ + GLL Sbjct: 182 ITTHEMAETYDRILVIELFEHMKNYELLLRKI----SEWISKDGLLFLEHICHKTFAYHY 237 Query: 194 APISDQMLEWRLGFWSQ 210 P+ D F + Sbjct: 238 EPLDDDDWFTEYVFPAG 254 >2AVN-A nrPDB Length = 260 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 34/205 (16%), Positives = 64/205 (31%), Gaps = 15/205 (7%) Query: 48 YECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKT--VLDVGAGTGILSIFCAQAGA 105 +E Y ++ + + + + Y I VLD+G GTG S+F + G Sbjct: 18 WEFYDRIARAYDSMYETPKWKLYHRLIGSFLEEYLKNPCRVLDLGGGTGKWSLFLQERGF 77 Query: 106 RRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPE-QVDAIVSEWMGYGLLHE 164 V + + + ARE N V+ E + P +A+++ +G L + Sbjct: 78 EVVLVDPSKEMLEVAREKGVKN-------VVEAKAEDLPFPSGAFEAVLA--LGDVLSYV 128 Query: 165 SMLSSVLHARTKWLKEGGLLLPA---SAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSC 221 + L GLL+ I + F G + Sbjct: 129 ENKDKAFSEIRRVLVPDGLLIATVDNFYTFLQQMIEKDAWDQITRFLKTQTTSVGTTLFS 188 Query: 222 LEGFATRCLMGHSEIVVQGLSGEDV 246 +A + S + + + Sbjct: 189 FNSYAFKPEDLDSLEGFETVDIRGI 213 >5I2H-A nrPDB Length = 364 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 38/85 (44%), Gaps = 1/85 (1%) Query: 74 ILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRV-YAVEASAIWQQAREVVRFNGLEDR 132 IL++ + G+ +LDV G+GI ++ Q + + + A E+ G+ DR Sbjct: 188 ILKDNSGSSGRVLLDVAGGSGIYTMAVLQKYPTWRGIIFDRPEVLKIAAELAEQTGVRDR 247 Query: 133 VHVLPGPVETVELPEQVDAIVSEWM 157 + + G + P D ++S + Sbjct: 248 LELHAGDMWVDPFPPADDILLSNVL 272 >2PJD-A nrPDB Length = 343 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 16/149 (10%) Query: 72 LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR-RVYAVEAS-AIWQQAREVVRFNGL 129 +L VLDVG G G+LS+ A+ + R+ + S + +R + NG+ Sbjct: 186 QLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGV 245 Query: 130 EDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASA 189 E V V+ + D I+S H+ M + L A ++ L + Sbjct: 246 EGEV-FASNVFSEVK--GRFDMIISNP----PFHDGM-QTSLDAAQTLIRGAVRHLNSGG 297 Query: 190 ELFIAPISDQMLEWRLGFWSQVKQHYGVD 218 EL I L + + + +G Sbjct: 298 ELRIVA------NAFLPYPDVLDETFGFH 320 >1DUS-A nrPDB Length = 194 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 48/121 (39%), Gaps = 3/121 (2%) Query: 66 RTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVR 125 + D ++ N + +LD+G G G++ I A A + A+E ++ Sbjct: 36 KVDKGTKILVENVVVDKDDDILDLGCGYGVIGIALADEVKSTTMADINRRAIKLAKENIK 95 Query: 126 FNGLED-RVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLL 184 N L++ + V+ + + + I++ + +L ++ + LK+ G + Sbjct: 96 LNNLDNYDIRVVHSDLYENVKDRKYNKIITNP--PIRAGKEVLHRIIEEGKELLKDNGEI 153 Query: 185 L 185 Sbjct: 154 W 154 >1DL5-A nrPDB Length = 317 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 31/139 (22%), Positives = 54/139 (38%), Gaps = 20/139 (14%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARR--VYAVEAS-AIWQQAREVVRFNGLEDRVHVLPG 138 +G VL++G GTG + ++ + V +VE S I + A+ V G+E+ + V Sbjct: 75 KGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGIENVIFVCGD 134 Query: 139 PVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD 198 V D I + + + LKEGG ++ PI+ Sbjct: 135 GYYGVPEFSPYDVIF------VTVGVDEVPETWFTQ---LKEGGRVI--------VPINL 177 Query: 199 QMLEWRLGFWSQVKQHYGV 217 ++ + F + K Y V Sbjct: 178 KLSRRQPAFLFKKKDPYLV 196 >1NKV-A nrPDB Length = 256 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 14/125 (11%) Query: 67 TDAYRLGILRNWAALRGKTVLDVGAGTG-ILSIFCAQAGARRVYAVEASAIWQ-QAREVV 124 T+ + R G +LD+G+G+G +L + G ++ S+++ QA+ Sbjct: 21 TEEKYATLGRVLRMKPGTRILDLGSGSGEMLCTWARDHGITG-TGIDMSSLFTAQAKRRA 79 Query: 125 RFNGLEDRVHVLPGPVETVELPEQVDA---IVSEWM-GYGLLHESMLSSVLHARTKWLKE 180 G+ +RVH + E+ D + + W+ G E +L+ + LK Sbjct: 80 EELGVSERVHFIHNDAAGYVANEKCDVAACVGATWIAGGFAGAEELLA-------QSLKP 132 Query: 181 GGLLL 185 GG++L Sbjct: 133 GGIML 137 >1VQ1-A nrPDB Length = 294 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 84 KTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW-QQAREVVRFNGLEDRVHVLPGP 139 KTV D+G G+G + + A+ V+A + S+ + AR+ +G+ DR V G Sbjct: 135 KTVADIGTGSGAIGVSVAKFSDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGE 191 >2YXD-A nrPDB Length = 183 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 7/65 (10%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVH---VLPG 138 + V+DVG G+G +++ A+ + VYA++ A EV + N + + ++ G Sbjct: 35 KDDVVVDVGCGSGGMTVEIAK-RCKFVYAID---YLDGAIEVTKQNLAKFNIKNCQIIKG 90 Query: 139 PVETV 143 E V Sbjct: 91 RAEDV 95 >4QDJ-A nrPDB Length = 238 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 42/105 (40%), Gaps = 12/105 (11%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA--IWQQAREVVRFNGLEDRVHVLPG 138 L G V D G G G LSI AQAGA VY + S + + ++ ++ + Sbjct: 61 LPGLLVCDAGCGVGSLSIPLAQAGA-LVYGSDISEKMVGEAQQKAQEVLAYGNQPTFMTQ 119 Query: 139 PVETVELPEQVDAIVSEWMGYGLLH-----ESMLSSVLHARTKWL 178 + L + D ++ + + + +M+S + + L Sbjct: 120 DLAQ--LGGKYDTVIC--LDVLIHYPTEEASAMISHLASLADRRL 160 >6AW7-A nrPDB Length = 228 Score = 37.0 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 48/115 (41%), Gaps = 11/115 (9%) Query: 85 TVLDVGAGTGILSIFCAQA---GARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVE 141 VL++GA G ++ A+ GAR + + ++++ F GL+D+V +L G + Sbjct: 61 LVLELGAYCGYSAVRMARLLSPGARLLTMEKNPDYAAITQQMLNFAGLQDKVTILIGASQ 120 Query: 142 T-VELPEQVD------AIVSEWMGYGLLHESMLSSV-LHARTKWLKEGGLLLPAS 188 + ++ D + W L +L L + L +++P + Sbjct: 121 DLIPQLKKYDVDTLDLVFLDHWKDRYLPDTILLEECGLLRKGTVLLADNVIVPGT 175 >3NJR-A nrPDB Length = 204 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 25/125 (20%), Positives = 48/125 (38%), Gaps = 15/125 (12%) Query: 71 RLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLE 130 R L A RG+ + D+G G+G +S+ AG R + + + ++ + GL Sbjct: 44 RALTLAALAPRRGELLWDIGGGSGSVSVEWCLAGGRAITIEPRADRIENIQKNIDTYGLS 103 Query: 131 DRVHVLPGP----VETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLP 186 R+ + G + + LPE V + ++ +WL G ++ Sbjct: 104 PRMRAVQGTAPAALADLPLPEAV-----------FIGGGGSQALYDRLWEWLAPGTRIVA 152 Query: 187 ASAEL 191 + L Sbjct: 153 NAVTL 157 >2ZLB-A nrPDB Length = 223 Score = 36.6 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 14/117 (11%) Query: 85 TVLDVGAGTGILSIFCAQA---GARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPV 140 VL++GA G ++ A+ GAR + +E + ++++ F GL+D+V +L G Sbjct: 63 LVLELGAYCGYSAVRMARLLQPGARLLT-MEMNPDYAAITQQMLNFAGLQDKVTILNGAS 121 Query: 141 ETV--ELPEQVD------AIVSEWMGYGLLHESMLSSV-LHARTKWLKEGGLLLPAS 188 + + +L ++ D + W L +L L + L +++P + Sbjct: 122 QDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGT 178 >5BP7-A nrPDB Length = 271 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 46/109 (42%), Gaps = 14/109 (12%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVY--AVEASAIWQQAREV-VRFNGLEDRVHVLPGP 139 G VLD+G+G+G + C A + ++ S ++ ++ G+ DRV + G Sbjct: 60 GTRVLDLGSGSG--EMLCTWARDHGIIGTGIDMSQLFTAQAKLRAEELGVADRVTFIHGD 117 Query: 140 VETVELPEQVDA---IVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 ++ + + W+G G+ + + L+ GG++L Sbjct: 118 ASGYVSDDKAGVAACVGATWIGGGVAG------TIELLARSLRPGGIIL 160 >3DMF-A nrPDB Length = 381 Score = 36.3 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQARE-VVRFNGLEDRVHVLPGP 139 +RG+ VLD+GAG G L++ A+ GA V VE + + + N L+ + + Sbjct: 232 VRGRQVLDLGAGYGALTLPLARMGAE-VVGVEDDLASVLSLQKGLEANALKAQA-LHSDV 289 Query: 140 VETVELPEQVDAIVS 154 E + + D IV+ Sbjct: 290 DEALTEEARFDIIVT 304 >3BUS-A nrPDB Length = 273 Score = 36.3 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 39/166 (23%), Positives = 59/166 (35%), Gaps = 9/166 (5%) Query: 44 DQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQA 103 + L++ + D ++ D TD ++ G VLDVG G G ++ A A Sbjct: 26 ENLHFGYWEDAG--ADVSVD-DATDRLTDEMIALLDVRSGDRVLDVGCGIGKPAVRLATA 82 Query: 104 GARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQ-VDAIVSEWMGYGL 161 RV + S QA GL +RV + + DA+ W L Sbjct: 83 RDVRVTGISISRPQVNQANARATAAGLANRVTFSYADAMDLPFEDASFDAV---WALESL 139 Query: 162 LHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGF 207 H L + L+ GG + A L +AP+ E F Sbjct: 140 HHMPDRGRALREMARVLRPGGTVAIADFVL-LAPVEGAKKEAVDAF 184 >3I9F-A nrPDB Length = 170 Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 42/112 (37%), Gaps = 13/112 (11%) Query: 75 LRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVH 134 L N + ++D G G G + + A ++Y ++ + I + + + + Sbjct: 10 LPNIFEGKKGVIVDYGCGNGFYCKYLLEF-ATKLYCIDINVIALKEVK----EKFDSVIT 64 Query: 135 VLPGPVETVELPE-QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + + E+P+ VD I+ V+ + LK+ G ++ Sbjct: 65 L----SDPKEIPDNSVDFIL---FANSFHDMDDKQHVISEVKRILKDDGRVI 109 >3P9N-A nrPDB Length = 189 Score = 35.9 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 39/161 (24%), Positives = 63/161 (39%), Gaps = 19/161 (11%) Query: 63 DRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVE--ASAIWQQA 120 DRVR + I+ L G VLD+ AG+G L + GA V VE + A Sbjct: 27 DRVRESLF--NIVTARRDLTGLAVLDLYAGSGALGLEALSRGAASVLFVESDQRSAAVIA 84 Query: 121 REVVRFNGLEDRVHVLPGPVETVELP---EQVDAIVSEWMGYGLLHESMLSSVLHAR--T 175 R + GL + G V V VD ++++ + + + ++L A Sbjct: 85 R-NIEALGLSG-ATLRRGAVAAVVAAGTTSPVDLVLADP--PYNVDSADVDAILAALGTN 140 Query: 176 KWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYG 216 W +EG + + A + L W G+ ++ YG Sbjct: 141 GWTREGTVAVVERAT------TCAPLTWPEGWRRWPQRVYG 175 >6DCC-A nrPDB Length = 309 Score = 35.9 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 39/99 (39%), Gaps = 9/99 (9%) Query: 29 REAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLD 88 R + L K++R Y D RL +L+ RG+ VLD Sbjct: 17 RGSPLPAAGFKKQQRKFQYGNYCKYYGYRNPSCEDG------RLRVLK-PEWFRGRDVLD 69 Query: 89 VGAGTGILSI-FCAQAGARRVYAVEA-SAIWQQAREVVR 125 +G G L++ + G R+ ++ S + AR+ +R Sbjct: 70 LGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIR 108 >2I6G-A nrPDB Length = 199 Score = 35.5 bits (80), Expect = 0.037, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 61/180 (33%), Gaps = 26/180 (14%) Query: 43 RDQLYY-ECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCA 101 RD+ Y+ E Y H +++A G+T LD+G G G S++ A Sbjct: 5 RDENYFTEKYGLTRTHSDVLA-------------AAKVVAPGRT-LDLGCGNGRNSLYLA 50 Query: 102 QAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGL 161 G V A + + E ++ D + + T+ + D I+S + Sbjct: 51 ANGYD-VTAWDKNPASMANLERIKAAEGLDNLQTDLVDLNTLTFDGEYDFILSTVV-MMF 108 Query: 162 LHESMLSSVLHARTKWLKEGGLLL-------PAS-AEL-FIAPISDQMLEWRLGFWSQVK 212 L + ++ + K GG L P + F + L W +K Sbjct: 109 LEAQTIPGLIANMQRCTKPGGYNLIVAAMDTPDFPCTVGFPFAFKEGELRRYYEGWDMLK 168 >3GXO-A nrPDB Length = 369 Score = 35.5 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 6/70 (8%) Query: 85 TVLDVGAGTGILSIFCAQAGA---RRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVE 141 T +D+G G G S+ A A R +E + ++ARE++ GL DR +LPG Sbjct: 205 TAVDIGGGRG--SLMAAVLDAFPGLRGTLLERPPVAEEARELLTGRGLADRCEILPGDFF 262 Query: 142 TVELPEQVDA 151 +P+ D Sbjct: 263 E-TIPDGADV 271 >1YUB-A nrPDB Length = 245 Score = 35.1 bits (79), Expect = 0.045, Method: Composition-based stats. Identities = 29/228 (12%), Positives = 77/228 (33%), Gaps = 20/228 (8%) Query: 62 ADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQA 120 + + ++ I++ TV ++G G G L+ A+ +++V ++E S ++ + Sbjct: 9 QNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKI-SKQVTSIELDSHLFNLS 67 Query: 121 REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE 180 E ++ N RV ++ + + P + Y ++ H T+ +K+ Sbjct: 68 SEKLKLN---TRVTLIHQDILQFQFPNKQR--------YKIVGNIP----YHLSTQIIKK 112 Query: 181 GGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG 240 ++ + A + + + L + +S + H + V Sbjct: 113 --VVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNS 170 Query: 241 LSGE-DVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHG 287 + + +L + + + F + + A H Sbjct: 171 VLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA 218 >4HGY-A nrPDB Length = 276 Score = 35.1 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 4/105 (3%) Query: 84 KTVLDVGAGTGILSIFCAQAGARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGPVET 142 + VL++G GTG ++ A G V+ VE+S + + RE + + V + G Sbjct: 64 RPVLELGVGTGRVAFPLADLGVE-VHGVESSEPMLDKLREKAAAHPNGNLVVPVLGNFAK 122 Query: 143 VELPEQVDAIVSEWMGY--GLLHESMLSSVLHARTKWLKEGGLLL 185 ++L EQ ++V LL + + + L+ GG + Sbjct: 123 LDLGEQRYSVVFAAFNTLFCLLGQDEQIDCMRQARELLEPGGTFV 167 >5EVJ-A nrPDB Length = 387 Score = 35.1 bits (79), Expect = 0.057, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 66/202 (32%), Gaps = 24/202 (11%) Query: 68 DAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARR--VYAVEASAIWQQAREVVR 125 + + A + G VLD+GAG+G + A+ + V V+ + Q + Sbjct: 69 EKFWGCGNPIPAGIEGLRVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTP-AQLEVAISH 127 Query: 126 FNGLE--------DRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSS-VLHARTK 176 + + + G +E ++ D+ + +++ S + VL + Sbjct: 128 ADAYARDKLGYGKSNMTFIQGEIEYLDRAGLEDSSFDLVISNCVINLSPDKARVLSEAYR 187 Query: 177 WLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEI 236 L GG + SD ++ RL V+ H + CL G Sbjct: 188 VLAPGGEMH----------FSDVYVDRRL--PQSVRSHPVLLGECLAGALYNNDFIRLAR 235 Query: 237 VVQGLSGEDVLARPQRFAQLEL 258 V + A + EL Sbjct: 236 KVGFTDPRQLEAEEIQIHDAEL 257 >4HTF-A nrPDB Length = 285 Score = 34.7 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 13/105 (12%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETV-- 143 VLD G G G +I A+ G + + ++ + +A++ G+ D + + + V Sbjct: 72 VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 131 Query: 144 ELPEQVDAI----VSEWMGYGLLHESMLSSVLHARTKWLKEGGLL 184 L VD I V EW+ S+L ++ L+ GG+L Sbjct: 132 HLETPVDLILFHAVLEWVADP---RSVLQTLWSV----LRPGGVL 169 >3MGG-A nrPDB Length = 276 Score = 34.7 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 51/142 (35%), Gaps = 17/142 (11%) Query: 51 YSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARR-VY 109 Y E + + + + + G VL+ G G G ++ A+ + Sbjct: 6 YVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEIT 65 Query: 110 AVEASAIW-QQAREVVRFNGLED----RVHVLPGPVETVELPEQVDAIVSEWMGYGLLHE 164 +++ S ++ARE NG+++ + ++ P E D I + E Sbjct: 66 SIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFED----SSFDHIF-----VCFVLE 116 Query: 165 SML--SSVLHARTKWLKEGGLL 184 + L + K LK GG + Sbjct: 117 HLQSPEEALKSLKKVLKPGGTI 138 >4KRI-A nrPDB Length = 433 Score = 34.3 bits (77), Expect = 0.087, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 63/177 (35%), Gaps = 9/177 (5%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPV 140 G+ +LD+G G G + A +V+ V+ S + A E V + + Sbjct: 222 TGQRMLDIGVGIGGGARQAASEFGLQVHGVDLSTNMLAVALERVHKEKDARVTYAVCDAC 281 Query: 141 ETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQM 200 E P D + S + H + + LK GG +L + +S+ Sbjct: 282 EYEFEPNSFDYVFSR---DCIQHIKDTDKLFSRIYRALKPGGKVLITMYGVGHGTLSESF 338 Query: 201 LEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLE 257 E+ +Q+Y ++ +E A + E+ +++L + + + Sbjct: 339 KEY-----VSQRQYYLKNLEQIEEIAKKTGFIDIEVENMTPRFKEILLEERERIEQD 390 >5U19-A nrPDB Length = 341 Score = 34.3 bits (77), Expect = 0.090, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 70/199 (35%), Gaps = 29/199 (14%) Query: 9 LESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYEC-------YSDVSVHEEMI 61 L SG + E T E R+A L+ D + + V + + + Sbjct: 60 LLSGTPVDPDELTREVGADGRQALLDSGMAVD---DGTTFSSPLRGHQLHGVVVLSDPDV 116 Query: 62 ADRVRTDAYRLGILRNWAALR------GKTVLDVGAGTGILSIFCAQAGARRVYAVEASA 115 + V+ Y + +R G LD+G G+G+LS+ A V V+ + Sbjct: 117 EEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLAD-RYESVLGVDVNP 175 Query: 116 IWQ-QAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIV---------SEWMGYGLLHES 165 +R NGL + V G + + IV +E++ E Sbjct: 176 RAVALSRLNAALNGLTN-VTFREGDMFE-PAEGRFSRIVFNSPTNEEGNEFVDLLEAGEP 233 Query: 166 MLSSVLHARTKWLKEGGLL 184 +L + + L+ GG++ Sbjct: 234 ILETFFRNVPRKLESGGIV 252 >6MRO-A nrPDB Length = 194 Score = 34.0 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 10/104 (9%) Query: 87 LDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHV--LPGPVETVE 144 LD+G G G +I A+ G V ++ + ++A + +E V V + G V ++ Sbjct: 37 LDIGCGRGENAIMLAKNGCD-VTGID---LAKRAISDAKAKAIERHVKVNFIVGNVLEMD 92 Query: 145 LP---EQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 ++ D ++ + + + E L H K LKEGG Sbjct: 93 QLFTEDEFDIVIDSGLFHVITDEERLLFTRHVH-KVLKEGGKYF 135 >2GPY-A nrPDB Length = 233 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 48/106 (45%), Gaps = 8/106 (7%) Query: 86 VLDVGAGTGILSIFCAQAGARR-VYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPVETV 143 +L++G G +I AQA + ++E +++A + V+ GLE R+ +L G + Sbjct: 58 ILEIGTAIGYSAIRMAQALPEATIVSIERDERRYEEAHKHVKALGLESRIELLFGDA--L 115 Query: 144 ELPEQVDAIVSEWMGYGLLH--ESMLSSVLHARTKWLKEGGLLLPA 187 +L E+++ + + + + ++ GGL+L Sbjct: 116 QLGEKLE--LYPLFDVLFIDAAKGQYRRFFDMYSPMVRPGGLILSD 159 >2YVL-A nrPDB Length = 248 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 68 DAYRLGILRNWAALRGKTVLDVGAGTG-ILSIFCAQAGARRVY-AVEASAIWQQAREVVR 125 D++ + + N + K VL+ G G+G +L++ AG + AVE ++ A++ ++ Sbjct: 79 DSFYIALKLNLN--KEKRVLEFGTGSGALLAVLSEVAGEVWTFEAVE--EFYKTAQKNLK 134 Query: 126 FNGLEDRVHVLPGPVETVELPEQV 149 L V + E+PE + Sbjct: 135 KFNLGKNVKFFNVDFKDAEVPEGI 158 >1DOH-A nrPDB Length = 283 Score = 34.0 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 29/75 (38%), Gaps = 8/75 (10%) Query: 64 RVRTDAYRLGIL----RNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAV----EASA 115 + R ++ I A+L GK L GAG GI + G R + ++ Sbjct: 6 QPRGESKYDAIPGPLGPQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTE 65 Query: 116 IWQQAREVVRFNGLE 130 ++ ++ NG + Sbjct: 66 SAEEVVAAIKKNGSD 80 >3C3P-A nrPDB Length = 210 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 10/106 (9%) Query: 84 KTVLDVGAGTGILSIFCAQA--GARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPV 140 + V+ G G G S + A+A + RV ++ + AR ++ NGL DRV + G Sbjct: 58 QLVVVPGDGLGCASWWFARAISISSRVVMIDPDRDNVEHARRMLHDNGLIDRVELQVGDP 117 Query: 141 ETVELPEQ-VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 + ++ +D + + + VL + L + LL+ Sbjct: 118 LGIAAGQRDIDILFMD----CDVFNGA--DVLERMNRCLAKNALLI 157 >3SM3-A nrPDB Length = 235 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 73/198 (36%), Gaps = 21/198 (10%) Query: 77 NWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW-QQAREVVRFNGLEDRVHV 135 + +LD+G G+G +S+ A G V ++ ++ + A R GL + Sbjct: 25 HNYLQEDDEILDIGCGSGKISLELASKG-YSVTGIDINSEAIRLAETAARSPGLNQK--- 80 Query: 136 LPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHA--RTKWLKEGGLLLPASAELFI 193 G ++ + + ++ L+SV R++ +KE +L A L++ Sbjct: 81 -TGGKAEFKVENASSLSFHDSSFDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYLYL 139 Query: 194 APISDQMLEWRLGFWSQVKQHYGVDMSCLEG----FATRCLMGHSEIVVQGLSGEDV--L 247 Q +L ++ Y D + A G +E + + +++ L Sbjct: 140 VEFG-QNWHLKL-----YRKRYLHDFPITKEEGSFLARDPETGETEFIAHHFTEKELVFL 193 Query: 248 ARPQRFAQLELSRAGLEQ 265 RF +++ R + Sbjct: 194 LTDCRF-EIDYFRVKELE 210 >5IKM-A nrPDB Length = 269 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 28/120 (23%) Query: 67 TDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAV-----------EASA 115 T R + RN GK + D+G G G S +CA G ++V V E Sbjct: 62 TAKLRWFVERNLVKPEGKVI-DLGCGRGGWSYYCA--GLKKVTEVKGYTKGGPGHEEPIP 118 Query: 116 IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART 175 + +V+ + +D V +P PE+ D ++ + + S ++ RT Sbjct: 119 MATYGWNLVKLHSGKD-VFFIP--------PEKCDTLLCD-----IGESSPNPTIEEGRT 164 >3TFW-A nrPDB Length = 248 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 13/109 (11%) Query: 84 KTVLDVGAGTGILSIFCAQA--GARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGP- 139 K +L++G G +I+ A+ ++ +EA A Q ARE ++ G++ RV + GP Sbjct: 65 KRILEIGTLGGYSTIWMARELPADGQLLTLEADAHHAQVARENLQLAGVDQRVTLREGPA 124 Query: 140 ---VETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 +E++ D I + + L ++ + G L++ Sbjct: 125 LQSLESLGECPAFDLIFID------ADKPNNPHYLRWALRYSRPGTLII 167 >3OPN-A nrPDB Length = 232 Score = 33.6 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%) Query: 72 LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAI 116 + + GKT LD+G+ TG + Q GA+ VYA++ Sbjct: 27 KALKEFHLEINGKTCLDIGSSTGGFTDVMLQNGAKLVYALDVGTN 71 >5BXY-A nrPDB Length = 158 Score = 33.6 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 85 TVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPVETV 143 + D+G+G G + I A+ R +E + ++AR+ + G+ D V G + Sbjct: 27 VLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEA 86 Query: 144 ELPEQ 148 ++ E Sbjct: 87 DISEA 91 >2IP2-A nrPDB Length = 334 Score = 33.2 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 12/118 (10%) Query: 49 ECYSDVSVHEE-----MIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGIL--SIFCA 101 + YS + + ++A + A+ + RG++ +DVG G+G L +I A Sbjct: 131 DFYSYLKRCPDAGRRFLLAMKASNLAFHE--IPRLLDFRGRSFVDVGGGSGELTKAILQA 188 Query: 102 QAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDA-IVSEWMG 158 + AR V ++ AR+ + +RV ++ G + E+P D ++S +G Sbjct: 189 EPSARGVM-LDREGSLGVARDNLSSLLAGERVSLVGGDMLQ-EVPSNGDIYLLSRIIG 244 >3VC2-A nrPDB Length = 312 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 54/165 (32%), Gaps = 19/165 (11%) Query: 42 ERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALR----------------GKT 85 + D LY+ Y V + D ++ Y ++ L T Sbjct: 62 DVDGLYHHHYGIGPVDRAALGDPEHSE-YEKKVIAELHRLESAQAEFLMDHLGQAGPDDT 120 Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVEL 145 ++D G G G + + RV V SA Q R L HV ++ Sbjct: 121 LVDAGCGRGGSMVMAHRRFGSRVEGVTLSA-AQADFGNRRARELRIDDHVRSRVCNMLDT 179 Query: 146 PEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAE 190 P A+ + W ++ L + +++LK GG + + Sbjct: 180 PFDKGAVTASWNNESTMYVD-LHDLFSEHSRFLKVGGRYVTITGC 223 >5MGZ-A nrPDB Length = 236 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 11/109 (10%) Query: 83 GKTVLDVGAGTGILS-IFCAQAGARRVYAVEASA-IWQQAREVV----RFNGLEDRVHVL 136 G+TV+D+ G+G L I ++ + + V+ S + + ARE + L Sbjct: 40 GQTVVDLCCGSGELEVILSSRFPSLNLVGVDLSEDMVRIAREYAAEQGKALEFRHGDAQL 99 Query: 137 PGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 +E L + D +VS + L + + K GG +L Sbjct: 100 LAGMED--LAGKADLVVSR---NAFHRLTRLPAAFDTMLRLAKPGGAVL 143 >3GRV-A nrPDB Length = 295 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPV 140 + VL++G G GIL+ A+ A++VY +E ++ A ++ + ++ G Sbjct: 50 KDDVVLEIGLGKGILTEELAK-NAKKVYVIEIDKSLEPYANKLKELYNN---IEIIWGDA 105 Query: 141 ETVEL 145 V+L Sbjct: 106 LKVDL 110 >3FYD-A nrPDB Length = 263 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPV 140 + VL++G G GIL+ A+ A++VY +E ++ A ++ + ++ G Sbjct: 21 KDDVVLEIGLGKGILTEELAK-NAKKVYVIEIDKSLEPYANKLKELYNN---IEIIWGDA 76 Query: 141 ETVEL 145 V+L Sbjct: 77 LKVDL 81 >5M58-A nrPDB Length = 230 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 42/109 (38%), Gaps = 11/109 (10%) Query: 83 GKTVLDVGAGTGILS-IFCAQAGARRVYAVEASAIW-----QQAREVVRFNGLEDRVHVL 136 G+TV+D+ G+G L I ++ + + V+ S A E + Sbjct: 40 GQTVVDLCCGSGELEIILTSRFPSLNLVGVDLSEDMVRIARDYAAEQGKELEFRHGDAQS 99 Query: 137 PGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 P +E L + D +VS + + L + + +K GG +L Sbjct: 100 PAGMED--LLGKADLVVSR---HAFHRLTRLPAGFDTMLRLVKPGGAIL 143 >1R74-A nrPDB Length = 294 Score = 32.8 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 64 RVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQARE 122 R RT Y+ +L + VLDV GTG+ SI + G V +V+AS + + A + Sbjct: 38 RSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALK 96 >4NEC-A nrPDB Length = 264 Score = 32.4 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 43/116 (37%), Gaps = 13/116 (11%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQ-QAREVVRFNGLEDRVHVL-PGPVETV 143 VLD G GTG ++ A G V ++ S AR+ GL V + Sbjct: 63 VLDAGCGTGEDALHLAGLG-YAVTGLDLSPTAISVARDKADARGLGAVFEVADALDLTGW 121 Query: 144 ELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQ 199 E E+ D ++ + + + L + A + + G + I ISD+ Sbjct: 122 E--ERFDTVIDSGLAHTFEGDR-LRAYATALHRACRPGAVA-------HILSISDR 167 >4LEC-A nrPDB Length = 212 Score = 32.4 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 80 ALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFN 127 LRG++ +++GAGTG++ I A GA V + + + V+ N Sbjct: 57 ELRGRSAVELGAGTGLVGIVAALLGAH-VTITDRKVALEFLKSNVQAN 103 >4F86-A nrPDB Length = 320 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 54/165 (32%), Gaps = 19/165 (11%) Query: 42 ERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALR----------------GKT 85 + D LY+ Y +V + D Y ++ L G T Sbjct: 70 DVDGLYHHHYGIGAVDHAALGD-PGDGGYEARLIAELHRLESAQAEFLLDHLGPVGPGDT 128 Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVEL 145 ++D G G G + Q +V V SA Q R L HV ++ Sbjct: 129 LVDAGCGRGGSMVMAHQRFGCKVEGVTLSA-AQAEFGNRRARELGIDDHVRSRVCNMLDT 187 Query: 146 PEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAE 190 P + + + W ++ L V +++L+ GG + + Sbjct: 188 PFEKGTVAASWNNESSMYVD-LHDVFAEHSRFLRVGGRYVTVTGC 231 >5EHG-A nrPDB Length = 276 Score = 32.4 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 42/114 (36%), Gaps = 28/114 (24%) Query: 73 GILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAV-----------EASAIWQQAR 121 + RN G+ + D+G G G S +CA G ++V V E + Sbjct: 65 FVERNMVIPEGRVI-DLGCGRGGWSYYCA--GLKKVTEVRGYTKGGPGHEEPVPMSTYGW 121 Query: 122 EVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART 175 +V+ ++ G PE+ D ++ + + S +V +RT Sbjct: 122 NIVK---------LMSGKDVFYLPPEKCDTLLCD-----IGESSPSPTVEESRT 161 >3BKX-A nrPDB Length = 275 Score = 32.4 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 66 RTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQA--GARRVYAVEASA 115 R A+RL I W G+ +L++G G G LS A + V ++ ++ Sbjct: 27 RQTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIAS 78 >2VS1-A nrPDB Length = 425 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 7/91 (7%) Query: 66 RTDAYR--LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIW-QQARE 122 +T++Y+ + + + G+ +LD+ +G G I+ A+ G V +++ + AR Sbjct: 272 QTNSYQAVNLVRKVSELVEGEKILDMYSGVGTFGIYLAKRGFN-VKGFDSNEFAIEMARR 330 Query: 123 VVRFNGLEDRVHVLPGPVETVELPEQVDAIV 153 V N ++ V +V + D ++ Sbjct: 331 NVEINNVDAEFEVASDREVSV---KGFDTVI 358 >2YXE-A nrPDB Length = 215 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 42/106 (39%), Gaps = 12/106 (11%) Query: 83 GKTVLDVGAGTGILSIFCAQ-AGAR-RVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGP 139 G VL++G G G + A+ G V ++E + ++A +R G ++ + ++ Sbjct: 78 GMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRKLGYDNVIVIVGDG 137 Query: 140 VETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 E D I + G + + LK+GG LL Sbjct: 138 TLGYEPLAPYDRIYTTAAG---------PKIPEPLIRQLKDGGKLL 174 >1XCL-A nrPDB Length = 235 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 55/169 (32%), Gaps = 18/169 (10%) Query: 51 YSDVSVHEEMIADRV--RTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRV 108 Y H +++ V R + + L AA RG VL+VG G I + QA + Sbjct: 26 YDTSDTHLQILGKPVMERWETPYMHSLAAAAASRGGRVLEVGFGMAIAASRVQQAPIKEH 85 Query: 109 YAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESML- 167 + +E + Q + +V L G E V P D L L Sbjct: 86 WIIECNDGVFQRLQNW-ALKQPHKVVPLKGLWEEV-APTLPD----GHFDGILYDTYPLS 139 Query: 168 SSVLHART---------KWLKEGGLLLPASAELFIAPISDQMLEWRLGF 207 H + LK GG+L + + + + + F Sbjct: 140 EETWHTHQFNFIKTHAFRLLKPGGILTYCNLTSWGELMKSKYTDITAMF 188 >2ESR-A nrPDB Length = 177 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 2/80 (2%) Query: 64 RVRTDAYRLGILRNWAA-LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQARE 122 R +D R I G VLD+ AG+G L+I G VE + Q + Sbjct: 12 RPTSDKVRGAIFNMIGPYFNGGRVLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQ 71 Query: 123 -VVRFNGLEDRVHVLPGPVE 141 + E+R +L E Sbjct: 72 DNIIMTKAENRFTLLKMEAE 91 >4PLP-A nrPDB Length = 479 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 31/210 (14%), Positives = 61/210 (29%), Gaps = 10/210 (4%) Query: 61 IADRVRTD-AYRLGILRNWAALRGKTVLDVGAGT--GILSIFCAQAGARRVYAVEASAIW 117 + R++ A R +L G T G G++S F QA + + Sbjct: 130 LKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEE 189 Query: 118 QQAREVVRFNGLE---DRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSV--LH 172 RE ++ +H+ + P+ D V+ W G + E + + Sbjct: 190 PTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWG 249 Query: 173 ARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMG 232 +W+ + + I + + YG ++ E + + Sbjct: 250 TFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLT 309 Query: 233 HSEIVVQGLSGEDV--LARPQRFAQLELSR 260 + Q + P A L L Sbjct: 310 VRDAAGQAVYRPTCHYAYHPCNDAVLSLHE 339 >6C4I-N nrPDB Length = 136 Score = 31.6 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 47/130 (36%), Gaps = 15/130 (11%) Query: 1 MSQPKK---RKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVH 57 M QPK+ RK+ G +GT+ G+ A+ R R T R+ + + Sbjct: 1 MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIE----------AAR 50 Query: 58 EEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRV-YAVEASAI 116 M R + + + + +G G G + + A +V Y ++ Sbjct: 51 RAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVP- 109 Query: 117 WQQAREVVRF 126 + ARE + Sbjct: 110 EELAREAFKL 119 >4V0R-A nrPDB Length = 892 Score = 31.6 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 41/114 (35%), Gaps = 28/114 (24%) Query: 73 GILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAV-----------EASAIWQQAR 121 + RN G+ + D+G G G S +CA G ++V V E + Sbjct: 62 FVERNMVIPEGRVI-DLGCGRGGWSYYCA--GLKKVTEVRGYTKGGPGHEEPVPMSTYGW 118 Query: 122 EVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART 175 +V+ ++ G PE+ D ++ + S +V +RT Sbjct: 119 NIVK---------LMSGKDVFYLPPEKCDTLLCDI-----GESSPSPTVEESRT 158 >4WXH-A nrPDB Length = 367 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 111 VEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIV 153 +E + AR ++ GL DRV V+ G LP + DAI+ Sbjct: 219 LEMAGTVDTARSYLKDEGLSDRVDVVEGDFFE-PLPRKADAII 260 >1ZQ9-A nrPDB Length = 285 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 2/76 (2%) Query: 72 LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREV-VRFNGLE 130 I+ A VL+VG GTG +++ A++V A E V+ + Sbjct: 18 NSIIDKAALRPTDVVLEVGPGTGNMTVKLL-EKAKKVVACELDPRLVAELHKRVQGTPVA 76 Query: 131 DRVHVLPGPVETVELP 146 ++ VL G V +LP Sbjct: 77 SKLQVLVGDVLKTDLP 92 >3HP7-A nrPDB Length = 291 Score = 31.6 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 14/110 (12%) Query: 80 ALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPG- 138 ++ +D+GA TG + Q GA+ VYAV+ ++V +DRV + Sbjct: 83 SVEDMITIDIGASTGGFTDVMLQNGAKLVYAVDVGTN-----QLVWKLRQDDRVRSMEQY 137 Query: 139 ---PVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 E V+ E + + S + + L+ +L A K L +GG ++ Sbjct: 138 NFRYAEPVDFTEGLPSFAS--IDVSFIS---LNLILPALAKILVDGGQVV 182 >5XFM-A nrPDB Length = 642 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 47/146 (32%), Gaps = 22/146 (15%) Query: 179 KEGGLLLPASAELFIAPISDQMLEWRLGFW-------------SQVKQHYGVDMSCLEGF 225 ++ G P F+ P SD M+ W+ + + +G CL Sbjct: 142 EQTGFRFPEQTTTFLCPQSDAMIGWKRTKPSYEEEYKADAPMSDRSQYGHGYTFPCLFRI 201 Query: 226 ATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPM 285 + SE G+ +R ++ L E G + + + Sbjct: 202 GNDGWVLVSET---GVDSRYCGSRLSDVSEGNLYTVAFPMAEENNGNG----TVAPAFAL 254 Query: 286 HGFAIWFQVTFPGGESEKPLVLSTSP 311 G W +T G+ KP+V +T P Sbjct: 255 PGATPWRTITV--GDHLKPIVETTVP 278 >4FGZ-A nrPDB Length = 266 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 45/121 (37%), Gaps = 6/121 (4%) Query: 72 LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVE-ASAIWQQAREVVRFNGLE 130 IL + VLD+G+G G ++ + + ++ S I A E V N Sbjct: 45 KKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNN-- 102 Query: 131 DRVHVLPGPVETVELPE-QVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASA 189 ++ + T E PE D I S L E+ + + KWLK G LL Sbjct: 103 -KIIFEANDILTKEFPENNFDLIYSRDAILHLSLENK-NKLFQKCYKWLKPTGTLLITDY 160 Query: 190 E 190 Sbjct: 161 C 161 >1D2C-A nrPDB Length = 292 Score = 31.3 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 64 RVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQARE 122 R RT Y+ +L VLDV GTG+ SI + G V +V+AS + + A + Sbjct: 38 RSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALK 96 >3E23-A nrPDB Length = 211 Score = 31.3 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 12/105 (11%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVET 142 G +L++G G G + AG V A + S + A E R G R + Sbjct: 44 GAKILELGCGAGYQAEAMLAAGFD-VDATDGSP--ELAAEASRRLGRPVRTMLF------ 94 Query: 143 VELPEQVDAIVSEWMGYGLLH--ESMLSSVLHARTKWLKEGGLLL 185 + +DA + W LLH L+ VL + LK GGL Sbjct: 95 -HQLDAIDAYDAVWAHACLLHVPRDELADVLKLIWRALKPGGLFY 138 >1P1B-A nrPDB Length = 199 Score = 31.3 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 43/136 (31%), Gaps = 16/136 (11%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVE 141 RG VL+VG G I + QA + + +E + Q + +V L G E Sbjct: 23 RGGRVLEVGFGMAIAASRVQQAPIKEHWIIECNDGVFQRLQNW-ALKQPHKVVPLKGLWE 81 Query: 142 TVELPEQVDAIVSEWMGYGLLHESML-SSVLHART---------KWLKEGGLLLPASAEL 191 V P D L L H + LK GG+L + Sbjct: 82 EV-APTLPD----GHFDGILYDTYPLSEETWHTHQFNFIKTHAFRLLKPGGILTYCNLTS 136 Query: 192 FIAPISDQMLEWRLGF 207 + + + + F Sbjct: 137 WGELMKSKYTDITAMF 152 >1I9G-A nrPDB Length = 280 Score = 31.3 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 14/124 (11%) Query: 74 ILRNWAALRGKTVLDVGAGTG--ILSIFCAQAGARRVYAVEA-SAIWQQAREVVR--FNG 128 I+ G VL+ GAG+G LS+ A A +V + E + + AR V + Sbjct: 91 IVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGCYGQ 150 Query: 129 LEDRVHVLPGPVETVELPEQ-VDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPA 187 D ++ + ELP+ VD V + + VL A ++ L GG+L+ Sbjct: 151 PPDNWRLVVSDLADSELPDGSVDRAVLDMLAPW--------EVLDAVSRLLVAGGVLMVY 202 Query: 188 SAEL 191 A + Sbjct: 203 VATV 206 >2B25-A nrPDB Length = 336 Score = 30.9 bits (68), Expect = 0.85, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Query: 72 LGILRNWAALRGKTVLDVGAGTGILSIFCAQA--GARRVYAVEA-SAIWQQAREVVRFNG 128 IL G TVL+ G+G+G +S+F ++A RV + E A++ + Sbjct: 95 NMILSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYK--H 152 Query: 129 LEDRVHVLPGPVETVELPEQVDAIVSEWMG 158 D + VE P+ VD I + G Sbjct: 153 WRDSWKL--SHVEEW--PDNVDFIHKDISG 178 >3BXO-A nrPDB Length = 239 Score = 30.9 bits (68), Expect = 0.86, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 41/103 (39%), Gaps = 11/103 (10%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPVETVE 144 +LDV GTG + +E S + AR+ + + G + Sbjct: 44 LLDVACGTGTHLEHFTKEFGDTA-GLELSEDMLTHARKRLPD------ATLHQGDMRDFR 96 Query: 145 LPEQVDAIVSEW--MGYGLLHESMLSSVLHARTKWLKEGGLLL 185 L + A+VS + +GY E + ++V L+ GG+++ Sbjct: 97 LGRKFSAVVSMFSSVGYLKTTEELGAAVASFAEH-LEPGGVVV 138 >6C5B-A nrPDB Length = 341 Score = 30.9 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 13/114 (11%) Query: 49 ECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRG-------KTVLDVGAGTGIL--SIF 99 + ++ H E ADRV +A + A+ KTV+D+GAG G L +I Sbjct: 136 SYFGYLAKHPE--ADRVFNEAQAGYTKQVAHAVVDAYDFSPFKTVIDIGAGYGPLLSAIL 193 Query: 100 CAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIV 153 +Q AR + + + Q A + + G+ DR + G VE+P D + Sbjct: 194 RSQPEARGIL-FDQPHVAQAAGKRLAEAGVGDRCGTVGGDFF-VEVPADGDVYI 245 >1UWV-A nrPDB Length = 433 Score = 30.9 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASA-IWQQAREVVRFNGLEDRVHVLPGPVET 142 VLD+ G G ++ A A V VE + ++ ++ R NGL++ V +E Sbjct: 290 VLDLFCGMGNFTLPLATQAAS-VVGVEGVPALVEKGQQNARLNGLQN-VTFYHENLEE 345 >6M83-A nrPDB Length = 263 Score = 30.9 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 49/131 (37%), Gaps = 8/131 (6%) Query: 56 VHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA 115 VH+ D R A ++R + + ++LDV GTG+ + A VE Sbjct: 25 VHQGKGKDYHREAADLAALVRRHSP-KAASLLDVACGTGMH----LRHLADSFGTVEGLE 79 Query: 116 IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYG-LLHESMLSSVLHAR 174 + + R + +H G + L + A+ + G L ++ L + L Sbjct: 80 LSADMLAIARRRNPDAVLH--HGDMRDFSLGRRFSAVTCMFSAIGHLAGQAELDAALERF 137 Query: 175 TKWLKEGGLLL 185 + G+++ Sbjct: 138 AAHVLPDGVVV 148 >4AZW-A nrPDB Length = 471 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 59/176 (33%), Gaps = 18/176 (10%) Query: 49 ECYSDVSVHEEMIADRVRTDAYRLGILR----NWAALRGK--TVLDVGAGTGILSIFCAQ 102 E Y + H E D R RL ++ N + G+ VLD+G G S+ A Sbjct: 27 EIYQTIFGHPEWDGDAARDCNQRLDLITEQYDNLSRALGRPLNVLDLGCAQGFFSLSLAS 86 Query: 103 AGARRVYAVE-ASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP---EQVDAIVSEWMG 158 GA + ++ R + N + G +E V + D + + Sbjct: 87 KGAT-IVGIDFQQENINVCRALAEENP-DFAAEFRVGRIEEVIAALEEGEFDLAIGLSVF 144 Query: 159 YGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQH 214 + ++H + V ++ ++ A + ++ W + ++ Sbjct: 145 HHIVHLHGIDEVKRLLSRLADVTQAVILELA------VKEEPFYWGVSQPDDPREL 194 >3MQ2-A nrPDB Length = 218 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 18/49 (36%), Gaps = 1/49 (2%) Query: 66 RTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGA-RRVYAVEA 113 R + + VLDVG G G A+ R V A++A Sbjct: 11 RVQEFSDAEFEQLRSQYDDVVLDVGTGDGKHPYKVARQNPSRLVVALDA 59 >4AZV-A nrPDB Length = 569 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 59/176 (33%), Gaps = 18/176 (10%) Query: 49 ECYSDVSVHEEMIADRVRTDAYRLGILR----NWAALRGK--TVLDVGAGTGILSIFCAQ 102 E Y + H E D R RL ++ N + G+ VLD+G G S+ A Sbjct: 27 EIYQTIFGHPEWDGDAARDCNQRLDLITEQYDNLSRALGRPLNVLDLGCAQGFFSLSLAS 86 Query: 103 AGARRVYAVE-ASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP---EQVDAIVSEWMG 158 GA + ++ R + N + G +E V + D + + Sbjct: 87 KGAT-IVGIDFQQENINVCRALAEENP-DFAAEFRVGRIEEVIAALEEGEFDLAIGLSVF 144 Query: 159 YGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQH 214 + ++H + V ++ ++ A + ++ W + ++ Sbjct: 145 HHIVHLHGIDEVKRLLSRLADVTQAVILELA------VKEEPFYWGVSQPDDPREL 194 >5F8E-A nrPDB Length = 377 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 36/165 (21%), Positives = 58/165 (35%), Gaps = 15/165 (9%) Query: 30 EAALERPRRTKRERDQLYYECYSDVSVHEEM--IADRVRTDAYRLGILRNWAALRGKT-- 85 ++ R RE + Y Y H+ M ++ V A +L L + Sbjct: 130 GEVEQKVIRCFREGGGVPYSEYPRF--HKLMAEMSGMVFDAALIDVVLPLVDGLPDRLRS 187 Query: 86 ---VLDVGAGTGILSIFCAQA-GARRVYAVEASAIWQQA-REVVRFNGLEDRVHVLPGPV 140 V D G G+G AQA GA R ++ S A E GL + + Sbjct: 188 GADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLAN-ATFERHDL 246 Query: 141 ETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 ++ D I + ++ + VL + L+ GG+LL Sbjct: 247 AELDKVGAYDVIT--VFD-AIHDQAQPARVLQNIYRALRPGGVLL 288 >3G7U-A nrPDB Length = 376 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 86 VLDVGAGTGILSIFCAQAG--ARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPV 140 V+D+ +G G LS+ A+AG + ++ AI A R +++ V +L + Sbjct: 5 VIDLFSGVGGLSLGAARAGFDVKMAVEIDQHAINTHAINFPRSLHVQEDVSLLNAEI 61 >2GLU-A nrPDB Length = 239 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 7/102 (6%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEAS-AIWQQAREVVRFNGLEDRVHVLPGPVETVE 144 VLD+GAG G + + V+A+ + + A + G+E+ V G E++ Sbjct: 25 VLDIGAGAG-HTALAFSPYVQECIGVDATKEMVEVASSFAQEKGVEN-VRFQQGTAESLP 82 Query: 145 LP-EQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLL 185 P + D I Y H S + + + LK+ G L Sbjct: 83 FPDDSFDIITCR---YAAHHFSDVRKAVREVARVLKQDGRFL 121 >2GS9-A nrPDB Length = 211 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 55/143 (38%), Gaps = 14/143 (9%) Query: 83 GKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVET 142 G+++L+VGAGTG + + + VE S A R + E Sbjct: 37 GESLLEVGAGTGY---WLRRLPYPQKVGVEPSE-AMLAVGRRRAPE----ATWVRAWGEA 88 Query: 143 VELP-EQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPA--SAELFIAPISDQ 199 + P E D ++ E + +L AR + L+ GG L+ A A + + Sbjct: 89 LPFPGESFDVVL--LFTTLEFVEDVERVLLEAR-RVLRPGGALVVGVLEALSPWAALYRR 145 Query: 200 MLEWRLGFWSQVKQHYGVDMSCL 222 + E + W+Q + D+ L Sbjct: 146 LGEKGVLPWAQARFLAREDLKAL 168 >2YR0-A nrPDB Length = 263 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 27/109 (24%), Positives = 50/109 (45%), Gaps = 14/109 (12%) Query: 82 RGKTVLDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPV 140 L++G GTG +++ G R + A++A +A+ + R+ + G++ +V V+ Sbjct: 39 EEPVFLELGVGTGRIALPLIARGYRYI-ALDADAAMLEVFRQ--KIAGVDRKVQVVQADA 95 Query: 141 ETVELPEQVDAIVSEWMGYGLLHESML----SSVLHARTKWLKEGGLLL 185 + LP++ G ++H L VL + LK GG LL Sbjct: 96 RAIPLPDE------SVHGVIVVHLWHLVPDWPKVLAEAIRVLKPGGALL 138 >6FDU-A nrPDB Length = 266 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 291 WFQVTFPGGESEKPLVLSTSPFHPATHWKQALL-YLNEPVQVEQDTDVSGEITLLPSRDN 349 +F +PG + L T P ++KQ ++ L + V + + G + + S++N Sbjct: 42 YFHTLYPGL-----IPLETFPPATIFNFKQKIISILEDKKAVLRGEPIKGPLPICCSKEN 96 Query: 350 PRR 352 RR Sbjct: 97 YRR 99 >3M70-A nrPDB Length = 286 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 37/97 (38%), Gaps = 3/97 (3%) Query: 86 VLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVEL 145 VLD+G G G S++ + G V + + + + + L + + Sbjct: 124 VLDLGCGQGRNSLYLSLLGYD-VTSWDHNENSIAFLNETKEKENLNISTALY-DINAANI 181 Query: 146 PEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGG 182 E D IVS + + L+ + S++ + GG Sbjct: 182 QENYDFIVSTVV-FMFLNRERVPSIIKNMKEHTNVGG 217 >1RQX-A nrPDB Length = 338 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 16/84 (19%) Query: 94 GILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPE----QV 149 G++ F A A RV V+ASA Q RE ++ + E + Sbjct: 205 GMVVGFAADGRADRVIGVDASAKPAQTRE---------QITRIARQTAEKVGLERDIMRA 255 Query: 150 DAIVSEWMG---YGLLHESMLSSV 170 D ++ E YGL +E L ++ Sbjct: 256 DVVLDERFAGPEYGLPNEGTLEAI 279 >2FHP-A nrPDB Length = 187 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 64 RVRTDAYRLGILRNWAA-LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQARE 122 R TD + I G LD+ +G+G L+I G + +E + A + Sbjct: 25 RPTTDKVKESIFNMIGPYFDGGMALDLYSGSGGLAIEAVSRGMDKSICIEKN---FAALK 81 Query: 123 VVRFN 127 V++ N Sbjct: 82 VIKEN 86 >5J3E-A nrPDB Length = 225 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 32/84 (38%), Gaps = 1/84 (1%) Query: 1 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM 60 MS+P+KR L G + G + AL + + ++ C ++S H M Sbjct: 1 MSRPRKR-LAGTSGSDKGLSGKRTKTENSGEALAKVEDSNPQKTSATKNCLKNLSSHWLM 59 Query: 61 IADRVRTDAYRLGILRNWAALRGK 84 ++ + + + L+ + Sbjct: 60 KSEPESRLEKGVDVKFSIEDLKAQ 83 >2B3T-A nrPDB Length = 276 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 86 VLDVGAGTGILSIFCAQAGAR-RVYAVEASAIWQ-QAREVVRFNGLEDRVHVLPGPVETV 143 +LD+G GTG +++ A + AV+ A+ + +++ +H+L + Sbjct: 113 ILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKN-IHILQSDWFSA 171 Query: 144 ELPEQVDAIVS 154 +Q IVS Sbjct: 172 LAGQQFAMIVS 182 >2OXT-A nrPDB Length = 265 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 5/76 (6%) Query: 80 ALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRF-NGLEDRVHVLPG 138 L G+ V D+G G G S + A V V A + EV R + Sbjct: 73 ELTGRVV-DLGCGRGGWSYYAASR--PHVMDVRAYTLGVGGHEVPRITESYGWNIVKFKS 129 Query: 139 PVETVELP-EQVDAIV 153 V+ LP E+ D I+ Sbjct: 130 RVDIHTLPVERTDVIM 145 >5XS0-A nrPDB Length = 215 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 17/43 (39%), Gaps = 1/43 (2%) Query: 92 GTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVH 134 G +S A G + Y +E + A E+ +NG + Sbjct: 51 GPEYISSRMAGGGQKVCY-IEGHRVINLANEMFGYNGWAHSIT 92 >4DCM-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 25/59 (42%), Gaps = 3/59 (5%) Query: 71 RLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGAR-RVYAVEASAIWQQ-AREVVRFN 127 R + L G+ V D+G G G++ + + +V V+ S + +R V N Sbjct: 212 RFFMQHLPENLEGEIV-DLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETN 269 >4MTL-A nrPDB Length = 244 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 81 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPV 140 + +L++GAG G++SI + GA+ V A + + + + N L+ H+ V Sbjct: 91 FQDAKILEIGAGPGLVSIVASILGAQ-VTATDLPDVLGNLQYNLLKNTLQCTAHL--PEV 147 Query: 141 ETVELPEQVD 150 + + E +D Sbjct: 148 KELVWGEDLD 157 >6F5Z-A nrPDB Length = 231 Score = 28.6 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 59/165 (35%), Gaps = 24/165 (14%) Query: 62 ADRVRTDAYRLGILRNWAAL---RGKTVLDVGAGTGILSIFCAQ--AGARRVYAVEASA- 115 D+ D + A + G TV+D+G G+G ++ + G R + ++ S Sbjct: 15 RDKGMEDRHWHTAKHALARMPVEEGDTVVDLGTGSGY-ALRALRDTKGIGRGFGLDGSPE 73 Query: 116 IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART 175 + Q AR + +D ++ + + VD + S M ++ Sbjct: 74 MVQNARA---YTDTDDLSFLVGDFDDLPFDDDSVDHVWS--MEAFYYAADPHHTLEEIA- 127 Query: 176 KWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMS 220 + LK GG + E + + ++H +DM+ Sbjct: 128 RILKPGGTFY----------CAVNYYEENVHS-HEWQEHISIDMT 161 >3G5T-A nrPDB Length = 299 Score = 27.8 bits (60), Expect = 8.8, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 28/60 (46%), Gaps = 4/60 (6%) Query: 68 DAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGA--RRVYAVEASAIWQQAREVVR 125 D Y+ ++ + K ++DVG G G ++ AQ ++ + SA + EV++ Sbjct: 24 DFYK--MIDEYHDGERKLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIK 81 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.128 0.320 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,347,027 Number of Sequences: 36641 Number of extensions: 513234 Number of successful extensions: 2508 Number of sequences better than 10.0: 162 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 131 Number of HSP's that attempted gapping in prelim test: 2216 Number of HSP's gapped (non-prelim): 269 length of query: 375 length of database: 10,336,785 effective HSP length: 99 effective length of query: 276 effective length of database: 6,709,326 effective search space: 1851773976 effective search space used: 1851773976 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)