BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96IY4 (423 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3D68-A nrPDB 827 0.0 3OSL-A nrPDB 678 0.0 3LMS-A nrPDB 650 0.0 3D4U-A nrPDB 531 e-151 1KWM-A nrPDB 343 7e-95 3GLJ-A nrPDB 335 2e-92 1NSA-A nrPDB 334 5e-92 4UIB-A nrPDB 326 2e-89 1ZLI-A nrPDB 318 4e-87 5MRV-A nrPDB 304 5e-83 1AYE-A nrPDB 273 9e-74 1PCA-A nrPDB 270 1e-72 5OM9-A nrPDB 263 1e-70 3KGQ-A nrPDB 263 1e-70 2BOA-A nrPDB 260 6e-70 4UEE-A nrPDB 253 1e-67 1DTD-A nrPDB 252 3e-67 4BD9-A nrPDB 251 5e-67 1CPB-B nrPDB 237 6e-63 2C1C-A nrPDB 165 4e-41 1JQG-A nrPDB 139 2e-33 3V7Z-A nrPDB 120 2e-27 1CPB-A nrPDB 82 6e-16 1QMU-A nrPDB 59 5e-09 3MN8-A nrPDB 39 0.003 2NSM-A nrPDB 37 0.012 1UWY-A nrPDB 36 0.036 3L2N-A nrPDB 35 0.067 5HXD-A nrPDB 32 0.59 1TOH-A nrPDB 31 0.97 5J6D-A nrPDB 29 4.7 6HNV-A nrPDB 28 5.5 5L01-A nrPDB 28 6.1 4HNK-A nrPDB 28 6.6 4AXV-A nrPDB 28 6.9 4GM2-A nrPDB 28 7.7 >3D68-A nrPDB Length = 424 Score = 827 bits (2137), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/400 (99%), Positives = 397/400 (99%) Query: 24 QSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH 83 QSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH Sbjct: 25 QSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH 84 Query: 84 LNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDM 143 LNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDM Sbjct: 85 LNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDM 144 Query: 144 LTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG 203 LTKIHIGSSFEKYPLYVLKVSGKEQ AKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG Sbjct: 145 LTKIHIGSSFEKYPLYVLKVSGKEQTAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG 204 Query: 204 IIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKH 263 IIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKH Sbjct: 205 IIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKH 264 Query: 264 WCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT 323 WCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT Sbjct: 265 WCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT 324 Query: 324 RSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFT 383 RSKSKDHEELSLVASEAVRAIEKISKN RYT+G GSETLYLAPGGGDDWIYDLGIKYSFT Sbjct: 325 RSKSKDHEELSLVASEAVRAIEKISKNIRYTYGQGSETLYLAPGGGDDWIYDLGIKYSFT 384 Query: 384 IELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 IELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV Sbjct: 385 IELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 424 >3OSL-A nrPDB Length = 401 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/401 (78%), Positives = 352/401 (87%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 FQ GQVL+ALPRTSRQVQ+LQN+TTTY+IVLWQPV A+ IVK +VHFFVNASDV NVKA Sbjct: 1 FQRGQVLSALPRTSRQVQILQNVTTTYKIVLWQPVAAEYIVKGYEVHFFVNASDVSNVKA 60 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 HLN S IP VL+ +VEDLI+QQ SNDT+SPRAS+SYYEQYHSLNEIYSWIE +TER+PD Sbjct: 61 HLNASRIPFRVLVENVEDLIRQQTSNDTISPRASSSYYEQYHSLNEIYSWIEVMTERYPD 120 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 M+ KIHIGSS+EKYPLYVLKVS KEQ AKNA+WIDCGIHAREWISPAFCLWF+G +T +Y Sbjct: 121 MVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAMWIDCGIHAREWISPAFCLWFVGSVTYYY 180 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G +TNLL+ +DFY+MPVVNVDGYDY+WKK+RMWRKNRS + N C+GTDLNRNFASK Sbjct: 181 GKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMWRKNRSLHEKNACVGTDLNRNFASK 240 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 HWC EGASSSSCSE YCG YPESEPEVKAVA FLRRNI IKAYISMHSYSQ IVFPYSY Sbjct: 241 HWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRRNIKHIKAYISMHSYSQKIVFPYSY 300 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 +RS+SKDHEELSLVA EAV A+E I +N RYTHG GSE+LYLAPGG DDWIYDLGIKYSF Sbjct: 301 SRSRSKDHEELSLVAREAVFAMENIHRNIRYTHGSGSESLYLAPGGSDDWIYDLGIKYSF 360 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRD G YGFLLPE YI+PTC EA AV+KIA HV++NV Sbjct: 361 TFELRDKGKYGFLLPESYIRPTCSEALVAVAKIASHVVKNV 401 >3LMS-A nrPDB Length = 309 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/309 (99%), Positives = 308/309 (99%) Query: 115 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 174 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI Sbjct: 1 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 60 Query: 175 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 234 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK Sbjct: 61 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 120 Query: 235 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 294 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS Sbjct: 121 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 180 Query: 295 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYT 354 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEK SKNTRYT Sbjct: 181 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYT 240 Query: 355 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 414 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK Sbjct: 241 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 300 Query: 415 IAWHVIRNV 423 IAWHVIRNV Sbjct: 301 IAWHVIRNV 309 >3D4U-A nrPDB Length = 309 Score = 531 bits (1368), Expect = e-151, Method: Compositional matrix adjust. Identities = 246/309 (79%), Positives = 272/309 (88%) Query: 115 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 174 AS+SYYEQYHSLNEIYSWIE +TER+PDM+ KIHIGSS+EKYPLYVLKVS KEQ AKNA+ Sbjct: 1 ASSSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAM 60 Query: 175 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 234 WIDCGIHAREWISPAFCLWF+G +T +YG +TNLL+ +DFY+MPVVNVDGYDY+WKK Sbjct: 61 WIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKK 120 Query: 235 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 294 +RMWRKNRS + N C+GTDLNRNFASKHWC EGASSSSCSE YCG YPESEPEVKAVA Sbjct: 121 DRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVAD 180 Query: 295 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYT 354 FLRRNI IKAYISMHSYSQ IVFPYSY+RS+SKDHEELSLVA EAV A+E I +N RYT Sbjct: 181 FLRRNIKHIKAYISMHSYSQKIVFPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYT 240 Query: 355 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 414 HG GSE+LYLAPGG DDWIYDLGIKYSFT ELRD G YGFLLPE YI+PTC EA AV+K Sbjct: 241 HGSGSESLYLAPGGSDDWIYDLGIKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAK 300 Query: 415 IAWHVIRNV 423 IA HV++NV Sbjct: 301 IASHVVKNV 309 >1KWM-A nrPDB Length = 402 Score = 343 bits (880), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 169/401 (42%), Positives = 250/401 (62%), Gaps = 6/401 (1%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + +++ L +T +I W+P + I V F V A D V+ Sbjct: 7 FEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVEN 66 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 L + + VL++++ ++++ Q + RA+ YE+Y+ I +W + + +P Sbjct: 67 VLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHSYEKYNKWETIEAWTQQVATENPA 123 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++++ IG++FE +Y+LKV GK K AI++DCG HAREWISPAFC WF+ + Y Sbjct: 124 LISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTY 182 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G Q T LL +DFYV+PV+N+DGY Y+W K+R WRK RS + + CIGTD NRNF + Sbjct: 183 GREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAG 242 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 WCE GAS + C ETYCG ESE E KA+A F+R ++ IKAY+++HSYSQ +++PYSY Sbjct: 243 -WCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSY 301 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 +++ EL+ +A V+ + + T+YT+G G+ T+Y A GG DDW YD GI+YSF Sbjct: 302 AYKLGENNAELNALAKATVKELASL-HGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSF 360 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRDTG YGFLLPE I+ TC E F A+ +A +V+ ++ Sbjct: 361 TFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHL 401 >3GLJ-A nrPDB Length = 401 Score = 335 bits (859), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 169/398 (42%), Positives = 241/398 (60%), Gaps = 6/398 (1%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + +L L +T +I W+P + I V F V A D+ V+ Sbjct: 7 FEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVED 66 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 L + + VL+ ++ +++ Q + R + YE+Y++ I +W + +T +PD Sbjct: 67 FLEQNELQYEVLINNLRSVLEAQFDSRV---RTTGHSYEKYNNWETIEAWTKQVTSENPD 123 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++++ IG++F +Y+LKV GK K AI++DCG HAREWIS AFC WF+ Y Sbjct: 124 LISRTAIGTTFLGNNIYLLKV-GKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTY 182 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G T L +DFYV+PV+N+DGY Y+W KNRMWRK RS A CIGTD NRNF + Sbjct: 183 GYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAG 242 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 WC GAS+ C ETYCG ESE E KA+A F+R N++ IKAY+++HSYSQ I++PYSY Sbjct: 243 -WCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSY 301 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 +++ EL+ +A AV+ + + T+YT+G G+ T+Y A GG DDW YD GIKYSF Sbjct: 302 DYKLPENNAELNNLAKAAVKELATLY-GTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSF 360 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI 420 T ELRD G YGF+LPE I+ TC E A+ + +V+ Sbjct: 361 TFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVL 398 >1NSA-A nrPDB Length = 395 Score = 334 bits (856), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 170/401 (42%), Positives = 248/401 (61%), Gaps = 6/401 (1%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + L L +T +I W+P + I V F V A D+ V+ Sbjct: 1 FEGEKVFRVNVEDENDISELHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVED 60 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 L + + VL+ ++ +++ Q D+VS R + YE+Y++ I +W E +T ++PD Sbjct: 61 FLEQNELQYEVLINNLRSVLEAQF--DSVS-RTTGHSYEKYNNWETIEAWTEQVTSKNPD 117 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++++ IG++F+ +Y+LKV GK + K AI++DCG HAREWIS AFC WF+ + Y Sbjct: 118 LISRSAIGTTFDGDNIYLLKV-GKPGSNKPAIFMDCGFHAREWISQAFCQWFVRDAVRTY 176 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G T L +DFYV+PV+N+DGY Y+W KNRMWRK RS A + C GTD NRNF + Sbjct: 177 GYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGSSCTGTDPNRNF-NA 235 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 WC GAS + C+ETYCG ESE E KA+A F+R N++ IKAY+++HSYSQ I++PYSY Sbjct: 236 GWCTVGASVNPCNETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSY 295 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 ++ EL+ +A AV+ + + T Y++G GS T+Y A GG DDW Y+ GIKYSF Sbjct: 296 DYKLPENDAELNSLAKGAVKELASL-YGTSYSYGPGSTTIYPAAGGSDDWAYNQGIKYSF 354 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRD G +GF+LPE I+ TC+E AV + + + ++ Sbjct: 355 TFELRDKGRFGFVLPESQIQATCQETMLAVKYVTNYTLEHL 395 >4UIB-A nrPDB Length = 307 Score = 326 bits (835), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 157/301 (52%), Positives = 206/301 (68%), Gaps = 3/301 (0%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 179 YE+Y++ I +W + +T +PD++++ IG++F +Y+LKV GK K AI++DCG Sbjct: 6 YEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKV-GKPGPNKPAIFMDCG 64 Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239 IHAREWIS AFC WF+ YG T L +DFYV+PV+N+DGY Y+W KNRMWR Sbjct: 65 IHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWR 124 Query: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299 K RS A CIGTD NRNF + WC GAS+ C ETYCG ESE E KA+A F+R N Sbjct: 125 KTRSTNAGTTCIGTDPNRNFDAG-WCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 183 Query: 300 INQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGS 359 ++ IKAY+S+HSYSQHIV+PYSY +++ EL+ +A AV+ + + T+YT+G G+ Sbjct: 184 LSSIKAYLSIHSYSQHIVYPYSYDYKLPENNAELNNLAKAAVKELATL-YGTKYTYGPGA 242 Query: 360 ETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419 TLYLAPGGGDDW YD GIKYSFT ELRD G YGF+LPE I+ TC E A+ + +V Sbjct: 243 TTLYLAPGGGDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYV 302 Query: 420 I 420 + Sbjct: 303 L 303 >1ZLI-A nrPDB Length = 309 Score = 318 bits (814), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 151/310 (48%), Positives = 211/310 (68%), Gaps = 3/310 (0%) Query: 114 RASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNA 173 RA+ YE+Y++ I +W + + +P ++++ IG++FE +Y+LKV GK K A Sbjct: 2 RATGHSYEKYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPA 60 Query: 174 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 233 I++DCG HAREWISPAFC WF+ + YG Q T LL +DFYV+PV+N+DGY Y+W Sbjct: 61 IFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWT 120 Query: 234 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 293 K+R WRK RS + + CIGTD NRNF + WCE GAS + C ETYCG ESE E KA+A Sbjct: 121 KSRFWRKTRSTHTGSSCIGTDPNRNFDAG-WCEIGASRNPCDETYCGPAAESEKETKALA 179 Query: 294 SFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRY 353 F+R ++ IKAY+++HSYSQ +++PYSY +++ EL+ +A V+ + + T+Y Sbjct: 180 DFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASL-HGTKY 238 Query: 354 THGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVS 413 T+G G+ T+Y A GG DDW YD GI+YSFT ELRDTG YGFLLPE I+ TC E F A+ Sbjct: 239 TYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIK 298 Query: 414 KIAWHVIRNV 423 +A +V+ ++ Sbjct: 299 YVASYVLEHL 308 >5MRV-A nrPDB Length = 355 Score = 304 bits (778), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 145/311 (46%), Positives = 205/311 (65%), Gaps = 3/311 (0%) Query: 103 QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL 161 +Q+I + +VSP + +Y Y YH + EIY W+ I+E++ +++T+ +G ++E +P+Y L Sbjct: 35 RQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYL 94 Query: 162 KVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMP 221 K+S K IW+DCGIHAREWI+PAFC WF+ I Q + + LLR +DFYV+P Sbjct: 95 KISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLP 154 Query: 222 VVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 281 V+N+DGY Y+W +R+WRK+RS + N C GTDLNRNF + WC GAS + +T+CG Sbjct: 155 VLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNAS-WCSIGASRNCQDQTFCGT 213 Query: 282 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV 341 P SEPE KAVASF+ + I +++MHSY Q I+ PY YT++KS +H E+ V +A Sbjct: 214 GPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAA 273 Query: 342 RAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYI 401 A+ K T Y G ++ LY + G DW D+GI +S+T ELRD+GTYGF+LPE I Sbjct: 274 NAL-KAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQI 332 Query: 402 KPTCREAFAAV 412 +PTC E AV Sbjct: 333 QPTCEETMEAV 343 >1AYE-A nrPDB Length = 401 Score = 273 bits (698), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 158/402 (39%), Positives = 225/402 (55%), Gaps = 14/402 (3%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL +P Q++ L L + L W+ T + H V +V V Sbjct: 4 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAV 59 Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFIT 137 K L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ + Sbjct: 60 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 119 Query: 138 ERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH 197 HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW Sbjct: 120 AEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAGIHAREWVTQATALWTANK 177 Query: 198 ITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNR 257 I YG T++L +D +++PV N DGY +S KNRMWRK RS + + C+G D NR Sbjct: 178 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 237 Query: 258 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 317 N+ + + GASS+ CS++Y G SE EVK++ F++ + ++KA+I +HSYSQ ++ Sbjct: 238 NWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFIILHSYSQLLM 295 Query: 318 FPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLG 377 FPY Y +K D +ELS VA +A +++ + T+Y G +Y A GG DW YD G Sbjct: 296 FPYGYKCTKLDDFDELSEVAQKAAQSLRSL-HGTKYKVGPICSVIYQASGGSIDWSYDYG 354 Query: 378 IKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419 IKYSF ELRDTG YGFLLP R I PT E + + I HV Sbjct: 355 IKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 396 >1PCA-A nrPDB Length = 403 Score = 270 bits (689), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 144/350 (41%), Positives = 214/350 (61%), Gaps = 8/350 (2%) Query: 77 VDNVKAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSW 132 + VK L GI ++++ DV+ L+ Q+Q+ R ++++ Y YH+L EIY + Sbjct: 57 IQAVKVFLEAHGIRYTIMIEDVQLLLDEEQEQMFASQGRARTTSTFNYATYHTLEEIYDF 116 Query: 133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCL 192 ++ + HP +++K+ IG S+E P+YVLK S + + AIWID GIH+REWI+ A + Sbjct: 117 MDILVAEHPALVSKLQIGRSYEGRPIYVLKFS-TGGSNRPAIWIDSGIHSREWITQASGV 175 Query: 193 WFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIG 252 WF IT+ YG +T +L +D ++ V N +G+ ++ NR+WRK RS + + C+G Sbjct: 176 WFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWRKTRSKASGSLCVG 235 Query: 253 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 312 +D NRN+ + + GASSS C+ETY G YP SE EVK++ F++ N N IKA+IS+HSY Sbjct: 236 SDSNRNWDAG-FGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNGN-IKAFISIHSY 293 Query: 313 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDW 372 SQ +++PY Y D EL+ +A AV A++ + T Y +G +Y A GG DW Sbjct: 294 SQLLLYPYGYKTQSPADKSELNQIAKSAVAALKSL-YGTSYKYGSIITVIYQASGGVIDW 352 Query: 373 IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422 Y+ GIKYSF+ ELRDTG GFLLP I PT +E + A+ I H + N Sbjct: 353 TYNQGIKYSFSFELRDTGRRGFLLPASQIIPTAQETWLALLTIMEHTLNN 402 >5OM9-A nrPDB Length = 419 Score = 263 bits (672), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 142/350 (40%), Positives = 211/350 (60%), Gaps = 8/350 (2%) Query: 77 VDNVKAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSW 132 + VK L GI ++ DV+ L+ Q+Q+ R++ ++ Y YH+L EIY + Sbjct: 72 IQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDF 131 Query: 133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCL 192 ++ + +P +++KI IG+++E P+YVLK S + + AIWID GIH+REW++ A + Sbjct: 132 LDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTGIHSREWVTQASGV 190 Query: 193 WFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIG 252 WF ITQ YG +T +L +D ++ V N DG+ ++ NRMWRK RS A + CIG Sbjct: 191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIG 250 Query: 253 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 312 D NRN+ + + GASS+ CSETY G + SE EVK++ F++ + N IKA+IS+HSY Sbjct: 251 VDPNRNWDAG-FGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSY 308 Query: 313 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDW 372 SQ +++PY Y D +EL ++ AV A+ + T++ +G + +Y A G DW Sbjct: 309 SQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASL-YGTKFNYGSIIKAIYQASGSTIDW 367 Query: 373 IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422 Y GIKYSFT ELRDTG YGFLLP I PT +E + A+ I H + + Sbjct: 368 TYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNH 417 >3KGQ-A nrPDB Length = 309 Score = 263 bits (671), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 135/304 (44%), Positives = 193/304 (63%), Gaps = 4/304 (1%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 179 Y YH+L+EIY +++ + HP +++K+ IG S+E P+YVLK S + + AIWID G Sbjct: 9 YATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFS-TGGSNRPAIWIDLG 67 Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239 IH+REWI+ A +WF T+ YG +T +L +D ++ V N DG+ ++ +NR+WR Sbjct: 68 IHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWR 127 Query: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299 K RS +++ C+G D NRN+ + + + GASSS CSETY G Y SE EVK++ F++ + Sbjct: 128 KTRSVTSSSLCVGVDANRNWDAG-FGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDH 186 Query: 300 INQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGS 359 N KA++S+HSYSQ +++PY YT D EL+ VA AV A++ + T Y +G Sbjct: 187 GN-FKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSL-YGTSYKYGSII 244 Query: 360 ETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419 T+Y A GG DW Y+ GIKYSFT ELRDTG YGFLLP I PT +E + V I H Sbjct: 245 TTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHT 304 Query: 420 IRNV 423 + N+ Sbjct: 305 LNNL 308 >2BOA-A nrPDB Length = 404 Score = 260 bits (665), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 151/407 (37%), Positives = 225/407 (55%), Gaps = 13/407 (3%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL R ++ L L + + L W+ ++ + V V + + Sbjct: 4 FFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSS----FNRPVDVLVPSVSLQAF 59 Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQ---ISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136 K+ L G+ +V + D++ L+ + + ++ R+S ++ Y YHSL IY ++ I Sbjct: 60 KSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNI 119 Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196 PD+ ++ IG SFE P+YVLK S + + A+W++ GIH+REWIS A +W Sbjct: 120 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 179 Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256 I Y T++L +D +++PV N DGY Y+ +NR+WRK RS + CIG D N Sbjct: 180 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPN 239 Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316 RN+ + + +GAS + CSE Y G + SE EVK+V F++++ N K +I +HSYSQ + Sbjct: 240 RNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN-FKGFIDLHSYSQLL 297 Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDL 376 ++PY Y+ K+ D EEL VA A +A+ +S T Y G T+Y A G DW YD Sbjct: 298 MYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN 356 Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 GIK++FT ELRDTGTYGFLLP I PT E + + I HV N+ Sbjct: 357 GIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 403 >4UEE-A nrPDB Length = 309 Score = 253 bits (646), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 131/303 (43%), Positives = 189/303 (62%), Gaps = 4/303 (1%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 179 Y YH+L EIY +++ + +P +++KI IG+++E P+YVLK S + + AIWID G Sbjct: 9 YATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTG 67 Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239 IH+REW++ A +WF ITQ YG +T +L +D ++ V N DG+ ++ NRMWR Sbjct: 68 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 127 Query: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299 K RS A + CIG D NRN+ + + GASS+ CSETY G + SE EVK++ F++ + Sbjct: 128 KTRSHTAGSLCIGVDPNRNWDAG-FGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDH 186 Query: 300 INQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGS 359 N IKA+IS+HSYSQ +++PY Y D +EL ++ AV A+ + T++ +G Sbjct: 187 GN-IKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASL-YGTKFNYGSII 244 Query: 360 ETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419 + +Y A G DW Y GIKYSFT ELRDTG YGFLLP I PT +E + A+ I H Sbjct: 245 KAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHT 304 Query: 420 IRN 422 + + Sbjct: 305 LNH 307 >1DTD-A nrPDB Length = 303 Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 134/301 (44%), Positives = 186/301 (61%), Gaps = 6/301 (1%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 179 + YH+L EI ++ + HP +++K++IGSSFE P+ VLK S K AIW+D G Sbjct: 3 FGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAG 60 Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239 IHAREW++ A LW I YG T++L +D +++PV N DGY +S KNRMWR Sbjct: 61 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 120 Query: 240 KNRS-FYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR 298 K RS A + C+G D NRN+ + + GASS+ CS++Y G SE EVK++ F++ Sbjct: 121 KTRSKVSAGSLCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 179 Query: 299 NINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHG 358 + ++KA+I +HSYSQ ++FPY Y +K D +ELS VA +A +++ ++ T+Y G Sbjct: 180 H-GKVKAFIILHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLSRL-HGTKYKVGPI 237 Query: 359 SETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWH 418 +Y A GG DW YD GIKYSF ELRDTG YGFLLP R I PT E + + I H Sbjct: 238 CSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEH 297 Query: 419 V 419 V Sbjct: 298 V 298 >4BD9-A nrPDB Length = 310 Score = 251 bits (640), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 132/304 (43%), Positives = 182/304 (59%), Gaps = 3/304 (0%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 179 Y YHSL IY ++ I PD+ ++ IG SFE P+YVLK S + + A+W++ G Sbjct: 9 YGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAG 68 Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239 IH+REWIS A +W I Y T++L +D +++PV N DGY Y+ +NR+WR Sbjct: 69 IHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWR 128 Query: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299 K RS + CIG D NRN+ + + +GAS + CSE Y G + SE EVK+V F++++ Sbjct: 129 KTRSRNPGSSCIGADPNRNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKH 187 Query: 300 INQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGS 359 N K +I +HSYSQ +++PY Y+ K+ D EEL VA A +A+ +S T Y G Sbjct: 188 GN-FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTC 245 Query: 360 ETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419 T+Y A G DW YD GIK++FT ELRDTGTYGFLLP I PT E + + I HV Sbjct: 246 TTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHV 305 Query: 420 IRNV 423 N+ Sbjct: 306 RDNL 309 >1CPB-B nrPDB Length = 217 Score = 237 bits (605), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 113/215 (52%), Positives = 150/215 (69%), Gaps = 2/215 (0%) Query: 209 TNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEG 268 T L +DFYV+PVVN+DGY Y+W NRMWRK RS A + C GTDLNRNF + WC G Sbjct: 5 TEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAG-WCSIG 63 Query: 269 ASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSK 328 AS++ CSETYCG ESE E KAVA F+R +++ IKAY+++HSYSQ +++PYSY K Sbjct: 64 ASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYSYDYKLPK 123 Query: 329 DHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRD 388 ++ EL+ +A AV+ + + T Y++G G+ T+Y A GG DDW YD GIKYSFT ELRD Sbjct: 124 NNVELNTLAKGAVKKLASL-HGTTYSYGPGATTIYPASGGSDDWAYDQGIKYSFTFELRD 182 Query: 389 TGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 G YGF+LPE I+PTC E A+ + +V+ ++ Sbjct: 183 KGRYGFVLPESQIQPTCEETMLAIKYVTSYVLEHL 217 >2C1C-A nrPDB Length = 312 Score = 165 bits (417), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 103/305 (33%), Positives = 158/305 (51%), Gaps = 19/305 (6%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGK--EQAAKNAIWID 177 Y+ Y L I ++++I E++PD+ T ++ SFE P+ +K+S E K I+ID Sbjct: 3 YDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFID 62 Query: 178 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237 GIHAREWISP W I + + +LL D+ ++PVVN DGY Y++ R Sbjct: 63 GGIHAREWISPPSVTWAIHKLVEDV----TENDLLEKFDWILLPVVNPDGYKYTFTNERF 118 Query: 238 WRKNRSFYANNH-----CIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAV 292 WRK RS NN+ C G D NRNF W G S+S CS+ Y G SE E + V Sbjct: 119 WRKTRS--TNNNPLSQICRGADGNRNFDFV-WNSIGTSNSPCSDIYAGTSAFSEVETRVV 175 Query: 293 ASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEK--ISKN 350 L ++ ++ Y++MHS+ I++P+ + S S++ L V I+ + Sbjct: 176 RDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNF 235 Query: 351 TRYTHGHGSETL-YLAPGGGDDWIYDLGIKYSFTIELR--DTGTYGFLLPERYIKPTCRE 407 YT G+ + + Y G +D+ + +G+ S+T EL +G GF LP +YI+ CRE Sbjct: 236 PPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRE 295 Query: 408 AFAAV 412 + + Sbjct: 296 TWEGI 300 >1JQG-A nrPDB Length = 433 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 102/389 (26%), Positives = 194/389 (49%), Gaps = 25/389 (6%) Query: 38 QVQVLQNLTTTYEIVLWQPVT----ADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSV 93 QV+++ + + +W ++V K + F N V+ L V + + Sbjct: 36 QVKLVHDFENDLMLDVWSDAVPGRPGKVLVPKFKREIFENFLKQSGVQYKLEVENVKEQL 95 Query: 94 LLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSF 153 ++ED + + + S R+ S+ ++ HS E+ ++++ + + P+++T + G SF Sbjct: 96 ---ELEDQLLAAAAAKSNSTRSRLSF-DKIHSYEEVDAYLQELAKEFPNVVTVVEGGKSF 151 Query: 154 EKYPLYVLKVSGK--EQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNL 211 E + L++S + A+K + + +H REW++ L+ I + I ++L Sbjct: 152 EGRSIKYLRISTTNFQDASKPVVMMQSLLHCREWVTLPATLYAIHKLV----IDVTESDL 207 Query: 212 LRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRS--FYANNHCIGTDLNRNFASKHWCEEGA 269 + +D+ ++PV N DGY +++ +R WRKNR+ + A N C+G DLNRNF +W + Sbjct: 208 INNIDWIILPVANPDGYVHTFGGDRYWRKNRATGYMAGNLCMGVDLNRNFG-MNWGT-AS 265 Query: 270 SSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKD 329 SSS CS+T+ G SEPE + + + N++ Y+ +HS+ I++ Y S + Sbjct: 266 SSSVCSDTFHGRSAFSEPESSVIRDIIAEHRNRMALYLDIHSFGSMILYGYGNGVLPS-N 324 Query: 330 HEELSLVASEAVRAIEKI--SKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIEL- 386 +L L+ + +AI+++ S N Y G+ LY A GG D+ +S+T EL Sbjct: 325 ALQLHLIGVQMAQAIDRVKWSSNKDYIVGNIFHVLYAASGGASDYAMQAAAPFSYTYELP 384 Query: 387 --RDTGTY-GFLLPERYIKPTCREAFAAV 412 R++ + GFL+ +I+ E + + Sbjct: 385 AYRNSVWFDGFLVDPDFIEQAGFETWEGI 413 >3V7Z-A nrPDB Length = 326 Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 95/309 (30%), Positives = 153/309 (49%), Gaps = 20/309 (6%) Query: 118 SYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAI 174 SY YH+ NE+ + I + +P+++ K IG S+E L+ +K+S G ++ + Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVL 63 Query: 175 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDG--YDYSW 232 + HARE ++ L+ + TQ Y + + TNL+ + Y++ +N DG YD S Sbjct: 64 YTALH-HAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISS 122 Query: 233 KKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAV 292 + WRKNR + + +GTDLNRN+ K C G+S S SETY G S PE A+ Sbjct: 123 GSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAM 182 Query: 293 ASFLRRNI----NQIKAYISMHSYSQHIVFPYSYTRSK---SKDHEELSLVASEAVRAIE 345 F+ + QIK I+ H+YS+ I++PY YT + ++ ++ + A Sbjct: 183 RDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMA----N 238 Query: 346 KISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTG-TYGFLLPERYI-KP 403 +++ YT S+ LY+ G DW Y ++FT E+ T GF P+ I + Sbjct: 239 TMAQTNGYTPQQASD-LYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRE 297 Query: 404 TCREAFAAV 412 T R A + Sbjct: 298 TSRNKEAVL 306 >1CPB-A nrPDB Length = 82 Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 35/76 (46%), Positives = 54/76 (71%), Gaps = 1/76 (1%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 179 YE+Y++ I +W E + +PD++++ IG++F +Y+LKV GK + K A+++DCG Sbjct: 6 YEKYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKV-GKPGSNKPAVFMDCG 64 Query: 180 IHAREWISPAFCLWFI 195 HAREWISPAFC WF+ Sbjct: 65 FHAREWISPAFCQWFV 80 >1QMU-A nrPDB Length = 380 Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 66/285 (23%), Positives = 125/285 (43%), Gaps = 43/285 (15%) Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178 ++H +++ ++ +P + +G S E LYV+++S G +A + Sbjct: 9 RHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEPEFKYIG 68 Query: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMW 238 +H E + L I ++ + +G + T+L++ ++MP +N DGY+ S + +R Sbjct: 69 NMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQEGDRGG 128 Query: 239 RKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR 298 R+ +NN+ DLNRNF + + + +PE AV S+L+ Sbjct: 129 TVGRN-NSNNY----DLNRNFPDQ---------------FFQVTDPPQPETLAVMSWLKT 168 Query: 299 NINQIKAYISMHSYSQHIVFPYSYTR------SKSKDH---EELSLVASEAVRAI----- 344 + A ++H S + +P+ SKS D ++L+L S+ + + Sbjct: 169 YPFVLSA--NLHGGSLVVNYPFDDDEQGIAIYSKSPDDAVFQQLALSYSKENKKMYQGSP 226 Query: 345 -EKISKNTRYTHG--HGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386 + + + HG +G++ Y PGG DW Y + TIEL Sbjct: 227 CKDLYPTEYFPHGITNGAQ-WYNVPGGMQDWNYLNTNCFEVTIEL 270 >3MN8-A nrPDB Length = 435 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 32/149 (21%), Positives = 65/149 (43%), Gaps = 12/149 (8%) Query: 119 YYEQYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQAAKNAIWID 177 +Y L ++++ +E + +P+ K+H +G S E L L++S + ++N + Sbjct: 39 HYASQEQLEDLFAGLE---KAYPNQ-AKVHFLGRSLEGRNLLALQIS-RNTRSRNLLTPP 93 Query: 178 ----CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 233 +H E + ++ ++ + I L+ D Y++P +N DGY S + Sbjct: 94 VKYIANMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQE 153 Query: 234 KNRMWRKNRSFYANNHCIGTDLNRNFASK 262 N N + + DLNR+F + Sbjct: 154 GNCESLPN--YVGRGNAANIDLNRDFPDR 180 >2NSM-A nrPDB Length = 439 Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust. Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 21/248 (8%) Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178 ++H +++ + + P + IG S E LYVL+ S G + + + Sbjct: 5 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 64 Query: 179 GIHAREWISPAFCLWFIGHI-TQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237 +H E + L + +F + L++ +++P +N DGY+ + + Sbjct: 65 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG-- 122 Query: 238 WRKNRSFY--ANNHCIGTDLNRNFASK----HWCEEGASSSSCSETYCGLYPESEPEVKA 291 N+ Y N+ G DLNRNF ++ E+ + + EPE +A Sbjct: 123 --PNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRA 180 Query: 292 VASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV---RAIEKIS 348 V ++ + +S + + +V Y Y +S + AS + +K++ Sbjct: 181 VIRWM----HSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLA 236 Query: 349 KNTRYTHG 356 K Y HG Sbjct: 237 KVYSYAHG 244 >1UWY-A nrPDB Length = 426 Score = 35.8 bits (81), Expect = 0.036, Method: Compositional matrix adjust. Identities = 34/144 (23%), Positives = 61/144 (42%), Gaps = 10/144 (6%) Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQAAKNAI---WID 177 YH + ++++ + + + +T +H IG S + L+VL V + + I Sbjct: 4 NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 62 Query: 178 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237 +H E + L I ++ G + TNL+ ++MP +N DG++ K + Sbjct: 63 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 122 Query: 238 WRKNRSFYANNHCIGTDLNRNFAS 261 + R Y DLNRNF Sbjct: 123 YSIGRENYNQ-----YDLNRNFPD 141 >3L2N-A nrPDB Length = 395 Score = 35.0 bits (79), Expect = 0.067, Method: Compositional matrix adjust. Identities = 34/151 (22%), Positives = 61/151 (40%), Gaps = 44/151 (29%) Query: 138 ERHPDMLTKI---------HIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISP 188 ERH D+++ + H+G + + + ++KV G + +K +IWI H E ++ Sbjct: 134 ERHLDLISAVQLHPLVSTEHLGLTLDGRDMTLVKV-GDDDPSKKSIWITARQHPGETMAE 192 Query: 189 AFCLWFIGHITQFYGIIGQYTN--------LLRLVDFYVMPVVNVDG------------- 227 W + G++ Q + LL +FY++P +N DG Sbjct: 193 ----WLV------EGLLNQLLDNDCPTSKALLDKANFYIVPNMNPDGSVRGHLRTNAVGA 242 Query: 228 -YDYSWKKNRMWRKNRSFYANN--HCIGTDL 255 + W+ + R +Y N H G DL Sbjct: 243 NLNREWQTPSLERSPEVYYVVNKMHETGVDL 273 >5HXD-A nrPDB Length = 237 Score = 32.0 bits (71), Expect = 0.59, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 23/89 (25%) Query: 218 YVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGAS----SSS 273 +V+ VN DG + N AN G DLNRNF + +W +EG + +S+ Sbjct: 74 HVVLCVNPDGCQLGLRAN----------AN----GVDLNRNFPAANW-KEGETVYRWNSA 118 Query: 274 CSET----YCGLYPESEPEVKAVASFLRR 298 E G P SEPE +A+ + R Sbjct: 119 AEERDVVLLTGDKPGSEPETQALCQLIHR 147 >1TOH-A nrPDB Length = 343 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 35/147 (23%), Positives = 55/147 (37%), Gaps = 27/147 (18%) Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISMHSY 312 + + H C E E YCG +S P+++ V+ FL+ + + +S + Sbjct: 86 KGLYATHACREHLEGFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDF 145 Query: 313 -----------SQHIVFPYSYTRSKSKD--HEELSLVASEAVRAIEKISKNTRYTHGHGS 359 +Q+I S S D HE L V A R + S++ G Sbjct: 146 LASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDI------GL 199 Query: 360 ETLYLAPGGGDDWIYDLGIKYSFTIEL 386 +L G D+ I L Y FT+E Sbjct: 200 ASL----GASDEEIEKLSTVYWFTVEF 222 >5J6D-A nrPDB Length = 307 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 41/199 (20%), Positives = 76/199 (38%), Gaps = 53/199 (26%) Query: 229 DYSWKKNRMWRKNRSFYAN---NHCIGT--------------------DLNRNFASKHWC 265 D+ K+ ++RK R ++A+ N+ G +LN+ + + H C Sbjct: 31 DHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPT-HAC 89 Query: 266 EEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISMHSYSQHIVF--- 318 E + YCG ++ P+++ V++FL+ +I + Y+S + + F Sbjct: 90 REYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVF 149 Query: 319 -----------PYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPG 367 P+ YT HE L V A + + S+ G +L G Sbjct: 150 HCTQYVRHSSDPF-YTPEPDTCHELLGHVPLLAEPSFAQFSQEI------GLASL----G 198 Query: 368 GGDDWIYDLGIKYSFTIEL 386 ++ + L Y FT+E Sbjct: 199 ASEEAVQKLATCYFFTVEF 217 >6HNV-A nrPDB Length = 524 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 2/33 (6%) Query: 373 IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTC 405 IYDL +KY F I D YG+L +Y KP Sbjct: 266 IYDLAVKYDFAIIEDD--PYGYLTLPKYEKPNI 296 >5L01-A nrPDB Length = 444 Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust. Identities = 24/117 (20%), Positives = 50/117 (42%), Gaps = 28/117 (23%) Query: 229 DYSWKKNRMWRKNRSFYAN---NHCIGT--------------------DLNRNFASKHWC 265 D+ K+ ++RK R ++A+ N+ G +LN+ + + H C Sbjct: 132 DHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPT-HAC 190 Query: 266 EEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISMHSYSQHIVF 318 E + YCG ++ P+++ V++FL+ +I + Y+S + + F Sbjct: 191 REYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAF 247 >4HNK-A nrPDB Length = 219 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Query: 64 KKKQVHFFVNAS-DVDNVKAHLNVSGIPCSVLLADVEDLIQQQI 106 K+K +H ++N++ D+DN K +N++GI + + DV + I + Sbjct: 71 KRKPIHLYINSTGDIDNNKI-INLNGITDVISIVDVINYISSDV 113 >4AXV-A nrPDB Length = 243 Score = 28.1 bits (61), Expect = 6.9, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 9/64 (14%) Query: 254 DLNRNFASKHWCEEGASSSSCSET-------YCGLYPESEPEVKAVASFLRRNINQIKAY 306 DLNR F +++W E G S T G + EPEV A+ S + + + K Sbjct: 102 DLNRAFPTQNWTEHGTVYRWSSHTPVRDVKVKTGDKEQLEPEVDALISLIE--LRRPKFV 159 Query: 307 ISMH 310 +S H Sbjct: 160 VSFH 163 >4GM2-A nrPDB Length = 205 Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Query: 64 KKKQVHFFVNAS-DVDNVKAHLNVSGIPCSVLLADVEDLIQQQI 106 K+K +H ++N++ D+DN K +N++GI + + DV + I + Sbjct: 57 KRKPIHLYINSTGDIDNNKI-INLNGITDVISIVDVINYISSDV 99 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3D68-A nrPDB 603 e-173 3GLJ-A nrPDB 587 e-168 3OSL-A nrPDB 587 e-168 1KWM-A nrPDB 580 e-166 1NSA-A nrPDB 580 e-166 1AYE-A nrPDB 548 e-156 2BOA-A nrPDB 540 e-154 5OM9-A nrPDB 533 e-152 1PCA-A nrPDB 525 e-149 3LMS-A nrPDB 486 e-138 1ZLI-A nrPDB 482 e-136 4UIB-A nrPDB 473 e-134 3D4U-A nrPDB 473 e-134 4BD9-A nrPDB 459 e-130 4UEE-A nrPDB 453 e-128 3KGQ-A nrPDB 452 e-127 1DTD-A nrPDB 451 e-127 5MRV-A nrPDB 430 e-121 1JQG-A nrPDB 412 e-115 2C1C-A nrPDB 355 2e-98 1CPB-B nrPDB 351 3e-97 3V7Z-A nrPDB 299 1e-81 1QMU-A nrPDB 249 2e-66 1CPB-A nrPDB 124 9e-29 Sequences not found previously or not previously below threshold: 1UWY-A nrPDB 153 1e-37 2NSM-A nrPDB 143 1e-34 3MN8-A nrPDB 134 7e-32 1PBA-A nrPDB 105 4e-23 1O6X-A nrPDB 89 3e-18 1PYT-A nrPDB 79 3e-15 4B6Z-A nrPDB 76 3e-14 3K2K-A nrPDB 72 6e-13 4A39-A nrPDB 63 3e-10 3L2N-A nrPDB 62 4e-10 3B2Y-A nrPDB 44 1e-04 2QVP-A nrPDB 40 0.001 5HXD-A nrPDB 39 0.004 4OKO-A nrPDB 36 0.024 3IEH-A nrPDB 36 0.025 4AXV-A nrPDB 34 0.12 1PVT-A nrPDB 32 0.62 4OZ5-A nrPDB 32 0.74 5B3R-A nrPDB 31 0.79 2X11-B nrPDB 31 1.0 4L0P-B nrPDB 30 1.6 3A22-A nrPDB 30 1.9 4U2L-A nrPDB 30 2.1 1NIO-A nrPDB 30 2.6 1QU3-A nrPDB 29 3.3 1X8H-A nrPDB 29 3.9 4PYT-A nrPDB 29 4.4 4D2I-A nrPDB 29 4.6 5AYL-A nrPDB 29 5.6 4EDP-A nrPDB 28 7.8 2UWM-A nrPDB 28 9.2 1WSU-A nrPDB 28 9.2 >3D68-A nrPDB Length = 424 Score = 603 bits (1554), Expect = e-173, Method: Composition-based stats. Identities = 396/400 (99%), Positives = 397/400 (99%) Query: 24 QSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH 83 QSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH Sbjct: 25 QSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH 84 Query: 84 LNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDM 143 LNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDM Sbjct: 85 LNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDM 144 Query: 144 LTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG 203 LTKIHIGSSFEKYPLYVLKVSGKEQ AKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG Sbjct: 145 LTKIHIGSSFEKYPLYVLKVSGKEQTAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG 204 Query: 204 IIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKH 263 IIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKH Sbjct: 205 IIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKH 264 Query: 264 WCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT 323 WCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT Sbjct: 265 WCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT 324 Query: 324 RSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFT 383 RSKSKDHEELSLVASEAVRAIEKISKN RYT+G GSETLYLAPGGGDDWIYDLGIKYSFT Sbjct: 325 RSKSKDHEELSLVASEAVRAIEKISKNIRYTYGQGSETLYLAPGGGDDWIYDLGIKYSFT 384 Query: 384 IELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 IELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV Sbjct: 385 IELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 424 >3GLJ-A nrPDB Length = 401 Score = 587 bits (1514), Expect = e-168, Method: Composition-based stats. Identities = 169/401 (42%), Positives = 243/401 (60%), Gaps = 6/401 (1%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + +L L +T +I W+P + I V F V A D+ V+ Sbjct: 7 FEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVED 66 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 L + + VL+ ++ +++ Q + R + YE+Y++ I +W + +T +PD Sbjct: 67 FLEQNELQYEVLINNLRSVLEAQFDSRV---RTTGHSYEKYNNWETIEAWTKQVTSENPD 123 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++++ IG++F +Y+LKV GK K AI++DCG HAREWIS AFC WF+ Y Sbjct: 124 LISRTAIGTTFLGNNIYLLKV-GKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTY 182 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G T L +DFYV+PV+N+DGY Y+W KNRMWRK RS A CIGTD NRNF + Sbjct: 183 GYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAG 242 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 WC GAS+ C ETYCG ESE E KA+A F+R N++ IKAY+++HSYSQ I++PYSY Sbjct: 243 -WCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSY 301 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 +++ EL+ +A AV+ + + T+YT+G G+ T+Y A GG DDW YD GIKYSF Sbjct: 302 DYKLPENNAELNNLAKAAVKELATL-YGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSF 360 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRD G YGF+LPE I+ TC E A+ + +V+ ++ Sbjct: 361 TFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL 401 >3OSL-A nrPDB Length = 401 Score = 587 bits (1512), Expect = e-168, Method: Composition-based stats. Identities = 316/401 (78%), Positives = 352/401 (87%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 FQ GQVL+ALPRTSRQVQ+LQN+TTTY+IVLWQPV A+ IVK +VHFFVNASDV NVKA Sbjct: 1 FQRGQVLSALPRTSRQVQILQNVTTTYKIVLWQPVAAEYIVKGYEVHFFVNASDVSNVKA 60 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 HLN S IP VL+ +VEDLI+QQ SNDT+SPRAS+SYYEQYHSLNEIYSWIE +TER+PD Sbjct: 61 HLNASRIPFRVLVENVEDLIRQQTSNDTISPRASSSYYEQYHSLNEIYSWIEVMTERYPD 120 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 M+ KIHIGSS+EKYPLYVLKVS KEQ AKNA+WIDCGIHAREWISPAFCLWF+G +T +Y Sbjct: 121 MVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAMWIDCGIHAREWISPAFCLWFVGSVTYYY 180 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G +TNLL+ +DFY+MPVVNVDGYDY+WKK+RMWRKNRS + N C+GTDLNRNFASK Sbjct: 181 GKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMWRKNRSLHEKNACVGTDLNRNFASK 240 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 HWC EGASSSSCSE YCG YPESEPEVKAVA FLRRNI IKAYISMHSYSQ IVFPYSY Sbjct: 241 HWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRRNIKHIKAYISMHSYSQKIVFPYSY 300 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 +RS+SKDHEELSLVA EAV A+E I +N RYTHG GSE+LYLAPGG DDWIYDLGIKYSF Sbjct: 301 SRSRSKDHEELSLVAREAVFAMENIHRNIRYTHGSGSESLYLAPGGSDDWIYDLGIKYSF 360 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRD G YGFLLPE YI+PTC EA AV+KIA HV++NV Sbjct: 361 TFELRDKGKYGFLLPESYIRPTCSEALVAVAKIASHVVKNV 401 >1KWM-A nrPDB Length = 402 Score = 580 bits (1495), Expect = e-166, Method: Composition-based stats. Identities = 169/401 (42%), Positives = 250/401 (62%), Gaps = 6/401 (1%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + +++ L +T +I W+P + I V F V A D V+ Sbjct: 7 FEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVEN 66 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 L + + VL++++ ++++ Q + RA+ YE+Y+ I +W + + +P Sbjct: 67 VLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHSYEKYNKWETIEAWTQQVATENPA 123 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++++ IG++FE +Y+LKV GK K AI++DCG HAREWISPAFC WF+ + Y Sbjct: 124 LISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTY 182 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G Q T LL +DFYV+PV+N+DGY Y+W K+R WRK RS + + CIGTD NRNF + Sbjct: 183 GREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAG 242 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 WCE GAS + C ETYCG ESE E KA+A F+R ++ IKAY+++HSYSQ +++PYSY Sbjct: 243 -WCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSY 301 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 +++ EL+ +A V+ + + T+YT+G G+ T+Y A GG DDW YD GI+YSF Sbjct: 302 AYKLGENNAELNALAKATVKELASL-HGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSF 360 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRDTG YGFLLPE I+ TC E F A+ +A +V+ ++ Sbjct: 361 TFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHL 401 >1NSA-A nrPDB Length = 395 Score = 580 bits (1495), Expect = e-166, Method: Composition-based stats. Identities = 167/401 (41%), Positives = 246/401 (61%), Gaps = 6/401 (1%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + L L +T +I W+P + I V F V A D+ V+ Sbjct: 1 FEGEKVFRVNVEDENDISELHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVED 60 Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPD 142 L + + VL+ ++ +++ Q + + R + YE+Y++ I +W E +T ++PD Sbjct: 61 FLEQNELQYEVLINNLRSVLEAQFDSVS---RTTGHSYEKYNNWETIEAWTEQVTSKNPD 117 Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++++ IG++F+ +Y+LKV GK + K AI++DCG HAREWIS AFC WF+ + Y Sbjct: 118 LISRSAIGTTFDGDNIYLLKV-GKPGSNKPAIFMDCGFHAREWISQAFCQWFVRDAVRTY 176 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 G T L +DFYV+PV+N+DGY Y+W KNRMWRK RS A + C GTD NRNF + Sbjct: 177 GYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGSSCTGTDPNRNFNAG 236 Query: 263 HWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY 322 WC GAS + C+ETYCG ESE E KA+A F+R N++ IKAY+++HSYSQ I++PYSY Sbjct: 237 -WCTVGASVNPCNETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSY 295 Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSF 382 ++ EL+ +A AV+ + + T Y++G GS T+Y A GG DDW Y+ GIKYSF Sbjct: 296 DYKLPENDAELNSLAKGAVKELASL-YGTSYSYGPGSTTIYPAAGGSDDWAYNQGIKYSF 354 Query: 383 TIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 T ELRD G +GF+LPE I+ TC+E AV + + + ++ Sbjct: 355 TFELRDKGRFGFVLPESQIQATCQETMLAVKYVTNYTLEHL 395 >1AYE-A nrPDB Length = 401 Score = 548 bits (1411), Expect = e-156, Method: Composition-based stats. Identities = 157/405 (38%), Positives = 226/405 (55%), Gaps = 14/405 (3%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTY--EIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL +P Q++ L L ++ W+ T + H V +V V Sbjct: 4 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAV 59 Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFIT 137 K L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ + Sbjct: 60 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 119 Query: 138 ERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH 197 HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW Sbjct: 120 AEHPGLVSKVNIGSSFENRPMNVLKFST--GGDKPAIWLDAGIHAREWVTQATALWTANK 177 Query: 198 ITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNR 257 I YG T++L +D +++PV N DGY +S KNRMWRK RS + + C+G D NR Sbjct: 178 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 237 Query: 258 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 317 N+ + + GASS+ CS++Y G SE EVK++ F++ + ++KA+I +HSYSQ ++ Sbjct: 238 NWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG-KVKAFIILHSYSQLLM 295 Query: 318 FPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLG 377 FPY Y +K D +ELS VA +A +++ + T+Y G +Y A GG DW YD G Sbjct: 296 FPYGYKCTKLDDFDELSEVAQKAAQSLRSL-HGTKYKVGPICSVIYQASGGSIDWSYDYG 354 Query: 378 IKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422 IKYSF ELRDTG YGFLLP R I PT E + + I HV + Sbjct: 355 IKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 399 >2BOA-A nrPDB Length = 404 Score = 540 bits (1390), Expect = e-154, Method: Composition-based stats. Identities = 150/407 (36%), Positives = 224/407 (55%), Gaps = 13/407 (3%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIV--LWQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL R ++ L L + + W+ ++ + V V + + Sbjct: 4 FFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSS----FNRPVDVLVPSVSLQAF 59 Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQ---ISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136 K+ L G+ +V + D++ L+ + + ++ R+S ++ Y YHSL IY ++ I Sbjct: 60 KSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNI 119 Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196 PD+ ++ IG SFE P+YVLK S + + A+W++ GIH+REWIS A +W Sbjct: 120 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 179 Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256 I Y T++L +D +++PV N DGY Y+ +NR+WRK RS + CIG D N Sbjct: 180 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPN 239 Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316 RN+ + + +GAS + CSE Y G + SE EVK+V F++++ N K +I +HSYSQ + Sbjct: 240 RNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN-FKGFIDLHSYSQLL 297 Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDL 376 ++PY Y+ K+ D EEL VA A +A+ +S T Y G T+Y A G DW YD Sbjct: 298 MYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN 356 Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 GIK++FT ELRDTGTYGFLLP I PT E + + I HV N+ Sbjct: 357 GIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 403 >5OM9-A nrPDB Length = 419 Score = 533 bits (1373), Expect = e-152, Method: Composition-based stats. Identities = 152/406 (37%), Positives = 227/406 (55%), Gaps = 14/406 (3%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTT--TYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL QVQ ++ L ++ W+ + V + V Sbjct: 20 FVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAH----PGSPIDVRVPFPSIQAV 75 Query: 81 KAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136 K L GI ++ DV+ L+ Q+Q+ R++ ++ Y YH+L EIY +++ + Sbjct: 76 KIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLL 135 Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196 +P +++KI IG+++E P+YVLK S + + AIWID GIH+REW++ A +WF Sbjct: 136 VAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTGIHSREWVTQASGVWFAK 194 Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256 ITQ YG +T +L +D ++ V N DG+ ++ NRMWRK RS A + CIG D N Sbjct: 195 KITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPN 254 Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316 RN+ + + GASS+ CSETY G + SE EVK++ F++ + N IKA+IS+HSYSQ + Sbjct: 255 RNWDAG-FGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSYSQLL 312 Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDL 376 ++PY Y D +EL ++ AV A+ + T++ +G + +Y A G DW Y Sbjct: 313 MYPYGYKTEPVPDQDELDQLSKAAVTALASL-YGTKFNYGSIIKAIYQASGSTIDWTYSQ 371 Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422 GIKYSFT ELRDTG YGFLLP I PT +E + A+ I H + + Sbjct: 372 GIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNH 417 >1PCA-A nrPDB Length = 403 Score = 525 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 154/406 (37%), Positives = 230/406 (56%), Gaps = 14/406 (3%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTT--TYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL QVQ ++ L ++ W+ + V + V Sbjct: 5 FVGHQVLRISVDDEAQVQKVKELEDLEHLQLDFWRGPA----RPGFPIDVRVPFPSIQAV 60 Query: 81 KAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136 K L GI ++++ DV+ L+ Q+Q+ R ++++ Y YH+L EIY +++ + Sbjct: 61 KVFLEAHGIRYTIMIEDVQLLLDEEQEQMFASQGRARTTSTFNYATYHTLEEIYDFMDIL 120 Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196 HP +++K+ IG S+E P+YVLK S + + AIWID GIH+REWI+ A +WF Sbjct: 121 VAEHPALVSKLQIGRSYEGRPIYVLKFS-TGGSNRPAIWIDSGIHSREWITQASGVWFAK 179 Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256 IT+ YG +T +L +D ++ V N +G+ ++ NR+WRK RS + + C+G+D N Sbjct: 180 KITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWRKTRSKASGSLCVGSDSN 239 Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316 RN+ + + GASSS C+ETY G YP SE EVK++ F++ N N IKA+IS+HSYSQ + Sbjct: 240 RNWDAG-FGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNGN-IKAFISIHSYSQLL 297 Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDL 376 ++PY Y D EL+ +A AV A++ + T Y +G +Y A GG DW Y+ Sbjct: 298 LYPYGYKTQSPADKSELNQIAKSAVAALKSL-YGTSYKYGSIITVIYQASGGVIDWTYNQ 356 Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422 GIKYSF+ ELRDTG GFLLP I PT +E + A+ I H + N Sbjct: 357 GIKYSFSFELRDTGRRGFLLPASQIIPTAQETWLALLTIMEHTLNN 402 >3LMS-A nrPDB Length = 309 Score = 486 bits (1252), Expect = e-138, Method: Composition-based stats. Identities = 308/309 (99%), Positives = 308/309 (99%) Query: 115 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 174 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI Sbjct: 1 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 60 Query: 175 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 234 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK Sbjct: 61 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 120 Query: 235 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 294 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS Sbjct: 121 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 180 Query: 295 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYT 354 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEK SKNTRYT Sbjct: 181 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYT 240 Query: 355 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 414 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK Sbjct: 241 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 300 Query: 415 IAWHVIRNV 423 IAWHVIRNV Sbjct: 301 IAWHVIRNV 309 >1ZLI-A nrPDB Length = 309 Score = 482 bits (1240), Expect = e-136, Method: Composition-based stats. Identities = 151/310 (48%), Positives = 211/310 (68%), Gaps = 3/310 (0%) Query: 114 RASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNA 173 RA+ YE+Y++ I +W + + +P ++++ IG++FE +Y+LKV GK K A Sbjct: 2 RATGHSYEKYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPA 60 Query: 174 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 233 I++DCG HAREWISPAFC WF+ + YG Q T LL +DFYV+PV+N+DGY Y+W Sbjct: 61 IFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWT 120 Query: 234 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 293 K+R WRK RS + + CIGTD NRNF + WCE GAS + C ETYCG ESE E KA+A Sbjct: 121 KSRFWRKTRSTHTGSSCIGTDPNRNFDAG-WCEIGASRNPCDETYCGPAAESEKETKALA 179 Query: 294 SFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRY 353 F+R ++ IKAY+++HSYSQ +++PYSY +++ EL+ +A V+ + + T+Y Sbjct: 180 DFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASL-HGTKY 238 Query: 354 THGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVS 413 T+G G+ T+Y A GG DDW YD GI+YSFT ELRDTG YGFLLPE I+ TC E F A+ Sbjct: 239 TYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIK 298 Query: 414 KIAWHVIRNV 423 +A +V+ ++ Sbjct: 299 YVASYVLEHL 308 >4UIB-A nrPDB Length = 307 Score = 473 bits (1216), Expect = e-134, Method: Composition-based stats. Identities = 157/309 (50%), Positives = 209/309 (67%), Gaps = 3/309 (0%) Query: 115 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 174 + YE+Y++ I +W + +T +PD++++ IG++F +Y+LKV GK K AI Sbjct: 1 TTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKV-GKPGPNKPAI 59 Query: 175 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 234 ++DCGIHAREWIS AFC WF+ YG T L +DFYV+PV+N+DGY Y+W K Sbjct: 60 FMDCGIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTK 119 Query: 235 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 294 NRMWRK RS A CIGTD NRNF + WC GAS+ C ETYCG ESE E KA+A Sbjct: 120 NRMWRKTRSTNAGTTCIGTDPNRNFDAG-WCTTGASTDPCDETYCGSAAESEKETKALAD 178 Query: 295 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYT 354 F+R N++ IKAY+S+HSYSQHIV+PYSY +++ EL+ +A AV+ + + T+YT Sbjct: 179 FIRNNLSSIKAYLSIHSYSQHIVYPYSYDYKLPENNAELNNLAKAAVKELATL-YGTKYT 237 Query: 355 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 414 +G G+ TLYLAPGGGDDW YD GIKYSFT ELRD G YGF+LPE I+ TC E A+ Sbjct: 238 YGPGATTLYLAPGGGDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKY 297 Query: 415 IAWHVIRNV 423 + +V+ ++ Sbjct: 298 VTNYVLGHL 306 >3D4U-A nrPDB Length = 309 Score = 473 bits (1216), Expect = e-134, Method: Composition-based stats. Identities = 246/309 (79%), Positives = 272/309 (88%) Query: 115 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 174 AS+SYYEQYHSLNEIYSWIE +TER+PDM+ KIHIGSS+EKYPLYVLKVS KEQ AKNA+ Sbjct: 1 ASSSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAM 60 Query: 175 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 234 WIDCGIHAREWISPAFCLWF+G +T +YG +TNLL+ +DFY+MPVVNVDGYDY+WKK Sbjct: 61 WIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKK 120 Query: 235 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 294 +RMWRKNRS + N C+GTDLNRNFASKHWC EGASSSSCSE YCG YPESEPEVKAVA Sbjct: 121 DRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVAD 180 Query: 295 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYT 354 FLRRNI IKAYISMHSYSQ IVFPYSY+RS+SKDHEELSLVA EAV A+E I +N RYT Sbjct: 181 FLRRNIKHIKAYISMHSYSQKIVFPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYT 240 Query: 355 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 414 HG GSE+LYLAPGG DDWIYDLGIKYSFT ELRD G YGFLLPE YI+PTC EA AV+K Sbjct: 241 HGSGSESLYLAPGGSDDWIYDLGIKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAK 300 Query: 415 IAWHVIRNV 423 IA HV++NV Sbjct: 301 IASHVVKNV 309 >4BD9-A nrPDB Length = 310 Score = 459 bits (1181), Expect = e-130, Method: Composition-based stats. Identities = 134/312 (42%), Positives = 187/312 (59%), Gaps = 4/312 (1%) Query: 113 PRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAK 171 R+S ++ Y YHSL IY ++ I PD+ ++ IG SFE P+YVLK S + + Sbjct: 1 ERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRR 60 Query: 172 NAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYS 231 A+W++ GIH+REWIS A +W I Y T++L +D +++PV N DGY Y+ Sbjct: 61 PAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYT 120 Query: 232 WKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKA 291 +NR+WRK RS + CIG D NRN+ + + +GAS + CSE Y G + SE EVK+ Sbjct: 121 QTQNRLWRKTRSRNPGSSCIGADPNRNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKS 179 Query: 292 VASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNT 351 V F++++ N K +I +HSYSQ +++PY Y+ K+ D EEL VA A +A+ +S T Sbjct: 180 VVDFIQKHGN-FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVS-GT 237 Query: 352 RYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAA 411 Y G T+Y A G DW YD GIK++FT ELRDTGTYGFLLP I PT E + Sbjct: 238 EYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLG 297 Query: 412 VSKIAWHVIRNV 423 + I HV N+ Sbjct: 298 LKTIMEHVRDNL 309 >4UEE-A nrPDB Length = 309 Score = 453 bits (1164), Expect = e-128, Method: Composition-based stats. Identities = 132/311 (42%), Positives = 194/311 (62%), Gaps = 5/311 (1%) Query: 113 PRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAK 171 R++ ++ Y YH+L EIY +++ + +P +++KI IG+++E P+YVLK S + + Sbjct: 1 ARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKR 59 Query: 172 NAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYS 231 AIWID GIH+REW++ A +WF ITQ YG +T +L +D ++ V N DG+ ++ Sbjct: 60 PAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFT 119 Query: 232 WKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKA 291 NRMWRK RS A + CIG D NRN+ + + GASS+ CSETY G + SE EVK+ Sbjct: 120 HSTNRMWRKTRSHTAGSLCIGVDPNRNWDAG-FGLSGASSNPCSETYHGKFANSEVEVKS 178 Query: 292 VASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNT 351 + F++ + N IKA+IS+HSYSQ +++PY Y D +EL ++ AV A+ + T Sbjct: 179 IVDFVKDHGN-IKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASL-YGT 236 Query: 352 RYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAA 411 ++ +G + +Y A G DW Y GIKYSFT ELRDTG YGFLLP I PT +E + A Sbjct: 237 KFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLA 296 Query: 412 VSKIAWHVIRN 422 + I H + + Sbjct: 297 LLTIMEHTLNH 307 >3KGQ-A nrPDB Length = 309 Score = 452 bits (1162), Expect = e-127, Method: Composition-based stats. Identities = 136/312 (43%), Positives = 198/312 (63%), Gaps = 5/312 (1%) Query: 113 PRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAK 171 R++ ++ Y YH+L+EIY +++ + HP +++K+ IG S+E P+YVLK S + + Sbjct: 1 ARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFS-TGGSNR 59 Query: 172 NAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYS 231 AIWID GIH+REWI+ A +WF T+ YG +T +L +D ++ V N DG+ ++ Sbjct: 60 PAIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFT 119 Query: 232 WKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKA 291 +NR+WRK RS +++ C+G D NRN+ + + + GASSS CSETY G Y SE EVK+ Sbjct: 120 HSQNRLWRKTRSVTSSSLCVGVDANRNWDAG-FGKAGASSSPCSETYHGKYANSEVEVKS 178 Query: 292 VASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNT 351 + F++ + N KA++S+HSYSQ +++PY YT D EL+ VA AV A++ + T Sbjct: 179 IVDFVKDHGN-FKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSL-YGT 236 Query: 352 RYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAA 411 Y +G T+Y A GG DW Y+ GIKYSFT ELRDTG YGFLLP I PT +E + Sbjct: 237 SYKYGSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLG 296 Query: 412 VSKIAWHVIRNV 423 V I H + N+ Sbjct: 297 VLTIMEHTLNNL 308 >1DTD-A nrPDB Length = 303 Score = 451 bits (1161), Expect = e-127, Method: Composition-based stats. Identities = 134/305 (43%), Positives = 187/305 (61%), Gaps = 6/305 (1%) Query: 119 YYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDC 178 + YH+L EI ++ + HP +++K++IGSSFE P+ VLK S K AIW+D Sbjct: 2 NFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST--GGDKPAIWLDA 59 Query: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMW 238 GIHAREW++ A LW I YG T++L +D +++PV N DGY +S KNRMW Sbjct: 60 GIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 119 Query: 239 RKNRSF-YANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLR 297 RK RS A + C+G D NRN+ + + GASS+ CS++Y G SE EVK++ F++ Sbjct: 120 RKTRSKVSAGSLCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIK 178 Query: 298 RNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGH 357 + ++KA+I +HSYSQ ++FPY Y +K D +ELS VA +A +++ ++ T+Y G Sbjct: 179 SHG-KVKAFIILHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLSRL-HGTKYKVGP 236 Query: 358 GSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAW 417 +Y A GG DW YD GIKYSF ELRDTG YGFLLP R I PT E + + I Sbjct: 237 ICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIME 296 Query: 418 HVIRN 422 HV + Sbjct: 297 HVRDH 301 >5MRV-A nrPDB Length = 355 Score = 430 bits (1105), Expect = e-121, Method: Composition-based stats. Identities = 145/318 (45%), Positives = 207/318 (65%), Gaps = 3/318 (0%) Query: 103 QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL 161 +Q+I + +VSP + +Y Y YH + EIY W+ I+E++ +++T+ +G ++E +P+Y L Sbjct: 35 RQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYL 94 Query: 162 KVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMP 221 K+S K IW+DCGIHAREWI+PAFC WF+ I Q + + LLR +DFYV+P Sbjct: 95 KISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLP 154 Query: 222 VVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 281 V+N+DGY Y+W +R+WRK+RS + N C GTDLNRNF + WC GAS + +T+CG Sbjct: 155 VLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNAS-WCSIGASRNCQDQTFCGT 213 Query: 282 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV 341 P SEPE KAVASF+ + I +++MHSY Q I+ PY YT++KS +H E+ V +A Sbjct: 214 GPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAA 273 Query: 342 RAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYI 401 A++ T Y G ++ LY + G DW D+GI +S+T ELRD+GTYGF+LPE I Sbjct: 274 NALKA-KYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQI 332 Query: 402 KPTCREAFAAVSKIAWHV 419 +PTC E AV + V Sbjct: 333 QPTCEETMEAVLSVLDDV 350 >1JQG-A nrPDB Length = 433 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 103/405 (25%), Positives = 197/405 (48%), Gaps = 25/405 (6%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVT----ADLIVKKKQVHFFVNASDVD 78 + V + QV+++ + + +W ++V K + F N Sbjct: 21 YDGHAVYQVDVASMDQVKLVHDFENDLMLDVWSDAVPGRPGKVLVPKFKREIFENFLKQS 80 Query: 79 NVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITE 138 V+ L V + + ++ED + + + S R+ S+ ++ HS E+ ++++ + + Sbjct: 81 GVQYKLEVENVKEQL---ELEDQLLAAAAAKSNSTRSRLSF-DKIHSYEEVDAYLQELAK 136 Query: 139 RHPDMLTKIHIGSSFEKYPLYVLKVSGK--EQAAKNAIWIDCGIHAREWISPAFCLWFIG 196 P+++T + G SFE + L++S + A+K + + +H REW++ L+ I Sbjct: 137 EFPNVVTVVEGGKSFEGRSIKYLRISTTNFQDASKPVVMMQSLLHCREWVTLPATLYAIH 196 Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRS--FYANNHCIGTD 254 + I ++L+ +D+ ++PV N DGY +++ +R WRKNR+ + A N C+G D Sbjct: 197 KLV----IDVTESDLINNIDWIILPVANPDGYVHTFGGDRYWRKNRATGYMAGNLCMGVD 252 Query: 255 LNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQ 314 LNRNF +W +SSS CS+T+ G SEPE + + + N++ Y+ +HS+ Sbjct: 253 LNRNFG-MNWGT-ASSSSVCSDTFHGRSAFSEPESSVIRDIIAEHRNRMALYLDIHSFGS 310 Query: 315 HIVFPYSYTRSKSKDHEELSLVASEAVRAIEKI--SKNTRYTHGHGSETLYLAPGGGDDW 372 I++ Y S + +L L+ + +AI+++ S N Y G+ LY A GG D+ Sbjct: 311 MILYGYGNGVLPS-NALQLHLIGVQMAQAIDRVKWSSNKDYIVGNIFHVLYAASGGASDY 369 Query: 373 IYDLGIKYSFTIEL---RDTGTY-GFLLPERYIKPTCREAFAAVS 413 +S+T EL R++ + GFL+ +I+ E + + Sbjct: 370 AMQAAAPFSYTYELPAYRNSVWFDGFLVDPDFIEQAGFETWEGIK 414 >2C1C-A nrPDB Length = 312 Score = 355 bits (912), Expect = 2e-98, Method: Composition-based stats. Identities = 102/303 (33%), Positives = 156/303 (51%), Gaps = 15/303 (4%) Query: 120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGK--EQAAKNAIWID 177 Y+ Y L I ++++I E++PD+ T ++ SFE P+ +K+S E K I+ID Sbjct: 3 YDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFID 62 Query: 178 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237 GIHAREWISP W I + + +LL D+ ++PVVN DGY Y++ R Sbjct: 63 GGIHAREWISPPSVTWAIHKLVE----DVTENDLLEKFDWILLPVVNPDGYKYTFTNERF 118 Query: 238 WRKNRSFYANNH---CIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 294 WRK RS N C G D NRNF W G S+S CS+ Y G SE E + V Sbjct: 119 WRKTRSTNNNPLSQICRGADGNRNFDFV-WNSIGTSNSPCSDIYAGTSAFSEVETRVVRD 177 Query: 295 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEK--ISKNTR 352 L ++ ++ Y++MHS+ I++P+ + S S++ L V I+ + Sbjct: 178 ILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPP 237 Query: 353 YTHGHGSETL-YLAPGGGDDWIYDLGIKYSFTIELR--DTGTYGFLLPERYIKPTCREAF 409 YT G+ + + Y G +D+ + +G+ S+T EL +G GF LP +YI+ CRE + Sbjct: 238 YTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETW 297 Query: 410 AAV 412 + Sbjct: 298 EGI 300 >1CPB-B nrPDB Length = 217 Score = 351 bits (901), Expect = 3e-97, Method: Composition-based stats. Identities = 113/219 (51%), Positives = 150/219 (68%), Gaps = 2/219 (0%) Query: 205 IGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHW 264 T L +DFYV+PVVN+DGY Y+W NRMWRK RS A + C GTDLNRNF + W Sbjct: 1 EIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAG-W 59 Query: 265 CEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTR 324 C GAS++ CSETYCG ESE E KAVA F+R +++ IKAY+++HSYSQ +++PYSY Sbjct: 60 CSIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYSYDY 119 Query: 325 SKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTI 384 K++ EL+ +A AV+ + + T Y++G G+ T+Y A GG DDW YD GIKYSFT Sbjct: 120 KLPKNNVELNTLAKGAVKKLASL-HGTTYSYGPGATTIYPASGGSDDWAYDQGIKYSFTF 178 Query: 385 ELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423 ELRD G YGF+LPE I+PTC E A+ + +V+ ++ Sbjct: 179 ELRDKGRYGFVLPESQIQPTCEETMLAIKYVTSYVLEHL 217 >3V7Z-A nrPDB Length = 326 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 96/313 (30%), Positives = 152/313 (48%), Gaps = 19/313 (6%) Query: 118 SYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSG--KEQAAKNAIW 175 SY YH+ NE+ + I + +P+++ K IG S+E L+ +K+S + + Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVL 63 Query: 176 IDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDG--YDYSWK 233 HARE ++ L+ + TQ Y + + TNL+ + Y++ +N DG YD S Sbjct: 64 YTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSG 123 Query: 234 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 293 + WRKNR + + +GTDLNRN+ K C G+S S SETY G S PE A+ Sbjct: 124 SYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMR 183 Query: 294 SFLRRNI----NQIKAYISMHSYSQHIVFPYSYTRSKSK---DHEELSLVASEAVRAIEK 346 F+ + QIK I+ H+YS+ I++PY YT + ++ ++ + A Sbjct: 184 DFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMAN----T 239 Query: 347 ISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTG-TYGFLLPERYI-KPT 404 +++ YT S+ LY+ G DW Y ++FT E+ T GF P+ I + T Sbjct: 240 MAQTNGYTPQQASD-LYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRET 298 Query: 405 CREAFAAVSKIAW 417 R AV +A Sbjct: 299 SRNK-EAVLYVAE 310 >1QMU-A nrPDB Length = 380 Score = 249 bits (635), Expect = 2e-66, Method: Composition-based stats. Identities = 66/285 (23%), Positives = 125/285 (43%), Gaps = 43/285 (15%) Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178 ++H +++ ++ +P + +G S E LYV+++S G +A + Sbjct: 9 RHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEPEFKYIG 68 Query: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMW 238 +H E + L I ++ + +G + T+L++ ++MP +N DGY+ S + +R Sbjct: 69 NMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQEGDRGG 128 Query: 239 RKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR 298 R+ +NN+ DLNRNF + + + +PE AV S+L+ Sbjct: 129 TVGRN-NSNNY----DLNRNFPDQ---------------FFQVTDPPQPETLAVMSWLKT 168 Query: 299 NINQIKAYISMHSYSQHIVFPYSYT------RSKSKDH---EELSLVASEAVRAI----- 344 + A ++H S + +P+ SKS D ++L+L S+ + + Sbjct: 169 YPFVLSA--NLHGGSLVVNYPFDDDEQGIAIYSKSPDDAVFQQLALSYSKENKKMYQGSP 226 Query: 345 -EKISKNTRYTHG--HGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386 + + + HG +G++ Y PGG DW Y + TIEL Sbjct: 227 CKDLYPTEYFPHGITNGAQ-WYNVPGGMQDWNYLNTNCFEVTIEL 270 >1UWY-A nrPDB Length = 426 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 53/284 (18%), Positives = 102/284 (35%), Gaps = 41/284 (14%) Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL---KVSGKEQAAKNAIWIDC 178 YH + ++++ + + + + IG S + L+VL + + + Sbjct: 4 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 63 Query: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMW 238 +H E + L I ++ G + TNL+ ++MP +N DG++ K + + Sbjct: 64 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 123 Query: 239 RKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR 298 R Y DLNRNF + + +PE AV +L+ Sbjct: 124 SIGRENYNQ-----YDLNRNFP---------------DAFEYNNVSRQPETVAVMKWLKT 163 Query: 299 NINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAIEKISK 349 + A ++H + +P+ Y+RS + D + +A + K Sbjct: 164 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 221 Query: 350 N----TRYTHGHGSE---TLYLAPGGGDDWIYDLGIKYSFTIEL 386 + +G + Y GG D+ Y + T+EL Sbjct: 222 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 265 >2NSM-A nrPDB Length = 439 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 56/300 (18%), Positives = 111/300 (37%), Gaps = 49/300 (16%) Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178 ++H +++ + + P + IG S E LYVL+ S G + + + Sbjct: 5 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 64 Query: 179 GIHAREWISPAFCLWFIGHITQFY-GIIGQYTNLLRLVDFYVMPVVNVDGYDY--SWKKN 235 +H E + L + + + + L++ +++P +N DGY+ + N Sbjct: 65 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPN 124 Query: 236 R-MWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLY----------PE 284 + + R+ AN G DLNRNF + + +E Y G + Sbjct: 125 KPGYLVGRN-NAN----GVDLNRNFPDLN------TYIYYNEKYGGPNHHLPLPDNWKSQ 173 Query: 285 SEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTR------------SKSKDHEE 332 EPE +AV ++ + A ++H + +PY + + + D + Sbjct: 174 VEPETRAVIRWMHSFNFVLSA--NLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKL 231 Query: 333 LSLVASEAVRAIEKISK----NTRYTHG--HGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386 +A A + + + G +G+ + Y G D+ Y + T+EL Sbjct: 232 FQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGA-SWYSLSKGMQDFNYLHTNCFEITLEL 290 >3MN8-A nrPDB Length = 435 Score = 134 bits (337), Expect = 7e-32, Method: Composition-based stats. Identities = 50/281 (17%), Positives = 99/281 (35%), Gaps = 31/281 (11%) Query: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAK---NAIWIDCG 179 Y S ++ + + +P+ +G S E L L++S ++ + Sbjct: 40 YASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIAN 99 Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239 +H E + ++ ++ + I L+ D Y++P +N DGY S + N Sbjct: 100 MHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGN--CE 157 Query: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299 ++ + DLNR+F + S + +PE A+ +++ Sbjct: 158 SLPNYVGRGNAANIDLNRDFPDRL---------EQSHVHQLRAQSRQPETAALVNWIVSK 208 Query: 300 INQIKAYISMHSYSQHIVFPYSYT--------RSKSKDHEELSLVASEAVRAIEKISKNT 351 + A + H + +PY + S + D +A + K Sbjct: 209 PFVLSA--NFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGN 266 Query: 352 R----YTHG--HGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386 ++ G +G+ Y GG D+ Y + TIEL Sbjct: 267 NCNDSFSGGITNGAH-WYELSGGMQDFNYAFSNCFELTIEL 306 >1CPB-A nrPDB Length = 82 Score = 124 bits (310), Expect = 9e-29, Method: Composition-based stats. Identities = 35/83 (42%), Positives = 55/83 (66%), Gaps = 1/83 (1%) Query: 115 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 174 + YE+Y++ I +W E + +PD++++ IG++F +Y+LKV GK + K A+ Sbjct: 1 TTGHSYEKYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKV-GKPGSNKPAV 59 Query: 175 WIDCGIHAREWISPAFCLWFIGH 197 ++DCG HAREWISPAFC WF+ Sbjct: 60 FMDCGFHAREWISPAFCQWFVRE 82 >1PBA-A nrPDB Length = 81 Score = 105 bits (262), Expect = 4e-23, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 31/75 (41%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82 F+ +V + L L +T +I W+P + I V F V A D+ V+ Sbjct: 7 FEGEKVFRVNVEDENDISELHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVED 66 Query: 83 HLNVSGIPCSVLLAD 97 L + + VL+ + Sbjct: 67 FLEQNELQYEVLINN 81 >1O6X-A nrPDB Length = 81 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 6/79 (7%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTY--EIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL +P Q++ L L ++ W+ T + H V +V V Sbjct: 7 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAV 62 Query: 81 KAHLNVSGIPCSVLLADVE 99 K L GI S+++ DV+ Sbjct: 63 KVFLESQGIAYSIMIEDVQ 81 >1PYT-A nrPDB Length = 94 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 33/92 (35%), Gaps = 6/92 (6%) Query: 23 FQSGQVLAALPRTSRQVQVLQNLTT--TYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80 F QVL +VQ ++ L ++ W+ + V + V Sbjct: 4 FVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPG----QPGSPIDVRVPFPSLQAV 59 Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVS 112 K L GI +++ DV+ L+ ++ S Sbjct: 60 KVFLEAHGIRYRIMIEDVQSLLDEEQEQMFAS 91 >4B6Z-A nrPDB Length = 405 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 50/305 (16%), Positives = 98/305 (32%), Gaps = 71/305 (23%) Query: 106 ISNDTVSPRASASYYEQYHSLNEIYSWIEFIT-----ERHPDMLTKIHIGSSFEKYPLYV 160 T++ + + Y++ E YS ++ P + + +G + E P+ + Sbjct: 111 FDGKTMTIDHTPEFDSIYYAYFEPYSEERHAAFLGAVQQLPQ-ASVVELGRTVEGRPMSL 169 Query: 161 LKVSG--KEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQ------FYGIIGQYTNLL 212 L + + A K +WI AR+ + WF+ + + + L Sbjct: 170 LTLGTPETDGAPKKKVWII----ARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLY 225 Query: 213 RLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSS 272 V F+++P +N DG + + G +LNR + + Sbjct: 226 DRVTFHIVPNMNPDGSVHG-------------NLRTNAAGANLNREWMA----------- 261 Query: 273 SCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY---TRSKSKD 329 E PEV AV + + + +H PY + + Sbjct: 262 --------PDAERSPEVLAVRDAIHAIGCDM--FFDIHGDEDL---PYVFVAGSEMLPSF 308 Query: 330 HEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDD-------WIYDLGIKYSF 382 E+ + + A + S + + HG Y A +D +I S Sbjct: 309 TEQQGKEQTAFIEAFKVASPDFQTEHG------YAASKYKEDALKLASKYIGHQFGCLSL 362 Query: 383 TIELR 387 T+E+ Sbjct: 363 TLEMP 367 >3K2K-A nrPDB Length = 403 Score = 71.7 bits (174), Expect = 6e-13, Method: Composition-based stats. Identities = 59/324 (18%), Positives = 108/324 (33%), Gaps = 72/324 (22%) Query: 118 SYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKE--QAAKNAIW 175 +Y+E Y E +S ++ P + + +G + E P+ ++ + + AAK +W Sbjct: 128 AYFEPYS--EERHSEFLGAVQQMPQ-ASVVELGRTVEGRPMSLVVLGTPDEAGAAKKKVW 184 Query: 176 IDCGIHAREWISPAFCLWFIGHITQ------FYGIIGQYTNLLRLVDFYVMPVVNVDGYD 229 I AR+ + WFI + + + L FY++P +N DG Sbjct: 185 II----ARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDGSV 240 Query: 230 YSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEV 289 + + G +LNR + E PEV Sbjct: 241 HG-------------NLRTNAAGANLNREWME-------------------PDAERSPEV 268 Query: 290 KAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEA-VRAIEKIS 348 V + + + +H + + + ++ E V A + + ++ S Sbjct: 269 LVVRDAIHAIGCDL--FFDIHG-DEDLPYVFAAGSEMLPGFTEQQRVEQSAFIDSFKRAS 325 Query: 349 KNTRYTHGHGSETLYLAPGGGDDWIYDLGIKY--------SFTIELRDTGTYGFLLPERY 400 + + HG Y PG + + L KY S T+E+ LP+ + Sbjct: 326 PDFQDEHG------YP-PGKYREDAFKLASKYIGHRFGCLSLTLEMPFKDNAN--LPDEH 376 Query: 401 IK-PTCREAFAA---VSKIAWHVI 420 I R A + I HV Sbjct: 377 IGWNGARSASLGAAMLGAILEHVR 400 >4A39-A nrPDB Length = 388 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 29/170 (17%), Positives = 58/170 (34%), Gaps = 41/170 (24%) Query: 144 LTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYG 203 + ++ +G+S + + +L+V + +W+ H E WF+ + + Sbjct: 144 VERLAVGTSVQGRDIELLRVRRHPDSHLK-LWVIAQQHPGEH----MAEWFMEGLIERLQ 198 Query: 204 I--IGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFAS 261 + LL D Y++P +N DG + + G DLNR + Sbjct: 199 RPDDTEMQRLLEKADLYLVPNMNPDGAFHG-------------NLRTNAAGQDLNRAW-- 243 Query: 262 KHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHS 311 E PEV V ++R+ + ++ +H Sbjct: 244 -----------------LEPSAERSPEVWFVQQEMKRHG--VDLFLDIHG 274 >3L2N-A nrPDB Length = 395 Score = 62.0 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 42/256 (16%), Positives = 93/256 (36%), Gaps = 53/256 (20%) Query: 140 HPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHIT 199 HP +++ H+G + + + ++KV G + +K +IWI AR+ W + + Sbjct: 146 HP-LVSTEHLGLTLDGRDMTLVKV-GDDDPSKKSIWIT----ARQHPGETMAEWLVEGLL 199 Query: 200 QFYGII--GQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNR 257 LL +FY++P +N DG + + +G +LNR Sbjct: 200 NQLLDNDCPTSKALLDKANFYIVPNMNPDGSVRGHLR-------------TNAVGANLNR 246 Query: 258 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 317 + + E PEV V + + + + + +H + + Sbjct: 247 EWQT-------------------PSLERSPEVYYVVN--KMHETGVDLFYDVHG-DEGLP 284 Query: 318 FPYSYTRSKSKD-HEELSLVASE--AVRAIEKISKNTRYTHG---HGSETLYLAPGGGDD 371 + + + ++L+ + + A ++ T + + G L +A + Sbjct: 285 YVFLAGCEGIPNYSDKLASLQQDFVAALSLASADFQTEFGYDKDEPGKANLTVAC----N 340 Query: 372 WIYDLGIKYSFTIELR 387 W+ + S T+E+ Sbjct: 341 WVANTFKCLSNTLEMP 356 >3B2Y-A nrPDB Length = 275 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 51/133 (38%), Gaps = 24/133 (18%) Query: 127 NEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWI 186 N+I ++ + E + K + S + + + + + S +++ ++ I G H E Sbjct: 23 NDIDAFYAQLAEEVNRLGLKKNTLGSVDSFAINLYQ-SASQRSDLPSLLISSGFHGEEAA 81 Query: 187 SPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYA 246 P L F+ G+ L V+ ++P+VN G+ + NR Sbjct: 82 GPWGMLHFLR------GLQPA---LFERVNLSLLPLVNPTGFKAGHRFNRF--------- 123 Query: 247 NNHCIGTDLNRNF 259 G + NR F Sbjct: 124 -----GENPNRGF 131 >2QVP-A nrPDB Length = 275 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 28/120 (23%) Query: 144 LTKIHIGSSFEK----YPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHIT 199 ++ +GS +PLY+L+ S ++A + I G H E P L F+ + Sbjct: 35 TERLGLGSKILGQAGHHPLYLLQ-SPGQKAGLPNLLISAGFHGEESAGPWGLLHFLSQL- 92 Query: 200 QFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNF 259 L + V+ V+P+VN G+ + N + G + NR F Sbjct: 93 --------DGELFKRVNLSVLPLVNPTGFAKGHRFNEL--------------GENPNRGF 130 >5HXD-A nrPDB Length = 237 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 54/158 (34%), Gaps = 36/158 (22%) Query: 148 HIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQ 207 H G S PL A++ + I G H E S + +T Sbjct: 19 HYGRSLLGAPLIWF---PAPAASRESGLILAGTHGDENSSVVTLSCALRTLTPS------ 69 Query: 208 YTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHW--C 265 L +V+ VN DG R AN G DLNRNF + +W Sbjct: 70 ------LRRHHVVLCVNPDG---CQLGLR-------ANAN----GVDLNRNFPAANWKEG 109 Query: 266 EEGASSSSCSE-----TYCGLYPESEPEVKAVASFLRR 298 E +S +E G P SEPE +A+ + R Sbjct: 110 ETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHR 147 >4OKO-A nrPDB Length = 312 Score = 36.2 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 41/113 (36%), Gaps = 24/113 (21%) Query: 156 YPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLV 215 Y LY LK + A+K + + G+H E + F + Sbjct: 62 YKLYALK-TKNWDASKPYVLVTGGVHGYETSGVQGAISFAQTRALEFARD---------Y 111 Query: 216 DFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEG 268 + ++P ++ GY+ NR W + A D NR+F + C+E Sbjct: 112 NIVILPCLSPWGYE---TINR-W----NPNA------LDPNRSFYLESGCQEA 150 >3IEH-A nrPDB Length = 276 Score = 36.2 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 34/96 (35%), Gaps = 23/96 (23%) Query: 164 SGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVV 223 S ++ ++ I G H E P L F+ + +L V+ ++P+V Sbjct: 59 SPAAKSGLPSLLISAGFHGEESAGPWGLLHFLSEAS---------ADLFERVNLSLLPLV 109 Query: 224 NVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNF 259 N G+ + N+ G + NR F Sbjct: 110 NPTGFSRGHRFNKY--------------GENPNRGF 131 >4AXV-A nrPDB Length = 243 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 61/175 (34%), Gaps = 38/175 (21%) Query: 143 MLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFY 202 ++T G S PL + E ++ I G H E S A + + Sbjct: 20 LITPTSYGKSVLGAPLLYFP-AQVESNSRGLIL--AGTHGDETASIAGLSCALRSLPA-- 74 Query: 203 GIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 + V+ +N D N++ + AN DLNR F ++ Sbjct: 75 ----------ECLKHDVILSMNPDA-------NQLGTRA---NANQ----VDLNRAFPTQ 110 Query: 263 HWCEEG-----ASSSSCSETYCGLYPES--EPEVKAVASFLRRNINQIKAYISMH 310 +W E G +S + + + EPEV A+ S + + + K +S H Sbjct: 111 NWTEHGTVYRWSSHTPVRDVKVKTGDKEQLEPEVDALISLIE--LRRPKFVVSFH 163 >1PVT-A nrPDB Length = 238 Score = 31.6 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 45/147 (30%), Gaps = 15/147 (10%) Query: 181 HAREWIS--PAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDY-------- 230 H RE I W L + Y + VN G+DY Sbjct: 2 HMRETIREIQKVAYWLAIKGLSEANAGNISVRLDERPEGYEVKSVNEYGFDYDGPEMYLL 61 Query: 231 -SWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEV 289 + +RM R+ + + +++ H + S + E PE Sbjct: 62 ITATGSRM-REVYEDDSKICLLHVLPGKHYEILHGNGKPTSEFPTHLMIHAKFKEMNPEK 120 Query: 290 KAVASFLRRNINQIKAYISMHSYSQHI 316 KA+ + + + +++ + + + Sbjct: 121 KAI---VHTHPLNLLTLMNLEEFQELL 144 >4OZ5-A nrPDB Length = 155 Score = 31.6 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 30/74 (40%), Gaps = 5/74 (6%) Query: 101 LIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITE-RHPDMLTKIHIGSSFEKYPLY 159 L+Q Q + + + + ++ H+ I + + E +HP +I + E PL+ Sbjct: 27 LMQGQENAILIHETSGDTVFQAPHAYEVI----DQVGEIKHPGFAVLNNIAVTQEGRPLF 82 Query: 160 VLKVSGKEQAAKNA 173 K + +N Sbjct: 83 ENKFKNRAGKVENE 96 >5B3R-A nrPDB Length = 228 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%) Query: 275 SETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYS-QHIVFPYSYTRSKSKDHEEL 333 ++ Y P + + + + ++ + +IK IS H + + ++S S EL Sbjct: 42 NDAYLIDTPITAKDTEKLVNWFIEHGYRIKGSISTHFHGDSTAGIEWLNSQSISTYASEL 101 Query: 334 -SLVASE--AVRAIEKISKNTRYTHGHGSETLYLAPGGGDD 371 + + + V+A S + + E Y PG D Sbjct: 102 TNELLKKDNKVQATNSFSGVSYSLIKNKIEVFYPGPGHTQD 142 >2X11-B nrPDB Length = 177 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 23/64 (35%), Gaps = 16/64 (25%) Query: 201 FYGIIGQYTNLLR-------------LVDFYVMPVVNVDGY---DYSWKKNRMWRKNRSF 244 Y I + L + YV+ +VN DGY D++ K + W NR Sbjct: 49 DYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPH 108 Query: 245 YANN 248 N Sbjct: 109 SPNG 112 >4L0P-B nrPDB Length = 143 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 3/39 (7%) Query: 213 RLVDFYVMPVVNVDGY---DYSWKKNRMWRKNRSFYANN 248 + YV+ +VN DGY D++ K + W NR N Sbjct: 49 DKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNG 87 >3A22-A nrPDB Length = 614 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 16/44 (36%) Query: 185 WISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGY 228 W + LW +YG T+LL D + P GY Sbjct: 190 WAAGQAPLWRTSTDIIYYGNQPSMTSLLSNFDQTLHPTAQHTGY 233 >4U2L-A nrPDB Length = 510 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 25/66 (37%), Gaps = 8/66 (12%) Query: 211 LLRLVDFYVMPVVN--------VDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASK 262 L+R D +P +N +G + + N MW + ++ +G D N S Sbjct: 293 LVRARDTGTLPNLNSEVGAGWGPNGNIMTARANHMWNPTGAHQSSIPALGIDAWDNSDSS 352 Query: 263 HWCEEG 268 + E Sbjct: 353 VFAEIA 358 >1NIO-A nrPDB Length = 247 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 37/103 (35%), Gaps = 6/103 (5%) Query: 7 AVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD-LIVKK 65 A LV I E F + GQ++ +P+ +L W ++ + + Sbjct: 150 AFLVIIQTTAEASRFKYIEGQIIKRIPKNEVPSPAALSLENE-----WSALSKQIQLAQT 204 Query: 66 KQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISN 108 F +DN + + + V+ +++ L+ +Q Sbjct: 205 NNGAFRTPVVIIDNKGQRVEIKDVNSKVVTNNIKLLLNKQNIA 247 >1QU3-A nrPDB Length = 917 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 28/86 (32%), Gaps = 9/86 (10%) Query: 290 KAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKS---KDHEELSLVASEAVRAIEK 346 KAV L +K HS +P+ + K + + S+ + I Sbjct: 372 KAVTDLLTEKGALLKLDFITHS------YPHDWRTKKPVIFRATPQWFASISKVRQDILD 425 Query: 347 ISKNTRYTHGHGSETLYLAPGGGDDW 372 +NT + G +Y +W Sbjct: 426 AIENTNFKVNWGKTRIYNMVRDRGEW 451 >1X8H-A nrPDB Length = 228 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 30/90 (33%), Gaps = 12/90 (13%) Query: 54 WQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSP 113 W P TA + K + +V N H + +G + + I VS Sbjct: 41 WTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAG----------GNAYWKSIGAKVVST 90 Query: 114 RASASYYEQYHSLNEIYSWIEFITERHPDM 143 R + + EI ++ +PD+ Sbjct: 91 RQTRDLMKS--DWAEIVAFTRKGLPEYPDL 118 >4PYT-A nrPDB Length = 309 Score = 28.9 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 37/232 (15%), Positives = 78/232 (33%), Gaps = 28/232 (12%) Query: 39 VQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNV---SGIPCSVLL 95 +Q L++L + I V D+ V+ + V G+ + Sbjct: 5 IQELKDLQVGKVLENEPLANHTTIKIGGPADCLVIPKDIQAVRDTMEVVKNHGVQWRAIG 64 Query: 96 ADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEK 155 L+ + V + L+ + E +T + ++ G S + Sbjct: 65 RGSNLLVLDEGIRGVVIKLGAG--------LDHMEIDGEQVTVGGGYSVVRLSTGISKKG 116 Query: 156 YPLYVLKV-SGKEQAAKNAIWIDCGIHARE---WISPAFCLW---FIGHITQFYGIIGQY 208 L L+ SG + A++++ G H + + A L+ + +T Sbjct: 117 --LSGLEFASGIPGSVGGAVYMNAGAHGSDISRILVKALILFEDGTMEWLTNEEMEFSYR 174 Query: 209 TNLLRLVD--FYVMPVVNV-----DGYDYSWKKNRMWRKNRSFYANNHCIGT 253 T++L+ + V+ + D +KN+ +RK + N C G+ Sbjct: 175 TSILQNKRPGICLEAVLQLEQKERDAIVAQMQKNKDYRKETQPVS-NPCAGS 225 >4D2I-A nrPDB Length = 500 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 31/76 (40%), Gaps = 1/76 (1%) Query: 77 VDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNE-IYSWIEF 135 + ++A L IP S L + +L+ + S + S++ E + E + + Sbjct: 231 TNGIRAALAAGQIPFSTLNSQFYELMADALETQGNSDKKSSAKDEVLNKFEEFMDRYSNV 290 Query: 136 ITERHPDMLTKIHIGS 151 I D++ K+ G Sbjct: 291 IDLTSSDIIEKVKRGK 306 >5AYL-A nrPDB Length = 783 Score = 28.5 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 104 QQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKI 147 Q V ++S YE +HS +I +IE + R+P +++ Sbjct: 511 QAYPTTVVFNQSSIHEYEGHHSAEQILEFIEDL--RNPSVVSLT 552 >4EDP-A nrPDB Length = 351 Score = 28.1 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 14/45 (31%), Gaps = 4/45 (8%) Query: 323 TRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPG 367 SK + E++ A V A YT + + G Sbjct: 110 DYSKIPNASEMNEKAKSTVEA----GYGPAYTLNSIGIVVDPSAG 150 >2UWM-A nrPDB Length = 258 Score = 27.7 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 16/35 (45%) Query: 35 TSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVH 69 + Q ++L++L Y + WQP + + + Sbjct: 136 SETQKKLLKDLEDKYRVSRWQPPSFKEVAGSFNLD 170 >1WSU-A nrPDB Length = 124 Score = 27.7 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 16/35 (45%) Query: 35 TSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVH 69 + Q ++L++L Y + WQP + + + Sbjct: 2 SETQKKLLKDLEDKYRVSRWQPPSFKEVAGSFNLD 36 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.131 0.360 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,939,142 Number of Sequences: 36641 Number of extensions: 629065 Number of successful extensions: 1844 Number of sequences better than 10.0: 58 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 1599 Number of HSP's gapped (non-prelim): 103 length of query: 423 length of database: 10,336,785 effective HSP length: 100 effective length of query: 323 effective length of database: 6,672,685 effective search space: 2155277255 effective search space used: 2155277255 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)