BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96I15 (445 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3GZD-A nrPDB 907 0.0 3A9Z-A nrPDB 715 0.0 5WGB-A nrPDB 214 4e-56 4EB7-A nrPDB 201 5e-52 5WT2-A nrPDB 199 3e-51 1ECX-A nrPDB 189 2e-48 3LVM-A nrPDB 187 6e-48 4ISY-A nrPDB 183 2e-46 4W91-A nrPDB 102 3e-22 5VPR-A nrPDB 80 1e-15 5XT5-A nrPDB 74 2e-13 6C9E-A nrPDB 72 6e-13 1T3I-A nrPDB 71 7e-13 4LW2-A nrPDB 67 1e-11 6MRE-A nrPDB 62 7e-10 4Q75-A nrPDB 61 9e-10 5HH9-A nrPDB 60 2e-09 3CAI-A nrPDB 40 0.002 2DR1-A nrPDB 38 0.011 3OP7-A nrPDB 33 0.22 2I3A-A nrPDB 32 0.59 6AP7-A nrPDB 32 0.63 3J0C-A nrPDB 32 0.67 1V2E-A nrPDB 32 0.72 4AOA-A nrPDB 31 0.99 5W25-A nrPDB 31 1.4 3PRL-A nrPDB 30 2.5 5DX5-A nrPDB 30 2.9 3QI6-A nrPDB 29 4.6 1YJS-A nrPDB 28 6.2 4CVQ-A nrPDB 28 6.4 4EGJ-A nrPDB 28 6.5 2E7J-A nrPDB 28 8.2 5O5C-A nrPDB 28 9.8 >3GZD-A nrPDB Length = 440 Score = 907 bits (2343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/438 (99%), Positives = 437/438 (99%) Query: 8 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSA 67 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSA Sbjct: 3 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSA 62 Query: 68 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH 127 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH Sbjct: 63 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH 122 Query: 128 HSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPT 187 HSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQ EVDDILAAVRPT Sbjct: 123 HSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQTEVDDILAAVRPT 182 Query: 188 TRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVED 247 TRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVED Sbjct: 183 TRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVED 242 Query: 248 LGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK 307 LGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK Sbjct: 243 LGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK 302 Query: 308 AAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPR 367 AAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPR Sbjct: 303 AAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPR 362 Query: 368 LQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV 427 LQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV Sbjct: 363 LQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV 422 Query: 428 DLVVQDLKQAVAQLEDQA 445 DLVVQDLKQAVAQLEDQA Sbjct: 423 DLVVQDLKQAVAQLEDQA 440 >3A9Z-A nrPDB Length = 432 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/415 (82%), Positives = 379/415 (91%), Gaps = 1/415 (0%) Query: 28 PERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIG 87 P RKVYMDYNATTPLEPEVIQA+T+AM EAWGNPSS Y AGRKAKDIIN AR SLAKMIG Sbjct: 16 PNRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLAKMIG 75 Query: 88 GKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDS 147 GKPQDIIFTSGGTESNNLVIHS V+ FH QT +G T SP +G +PHFIT +VEHDS Sbjct: 76 GKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQGRTVDQISPEEGTRPHFITCTVEHDS 135 Query: 148 IRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVP 207 IRLPLEHLVE+QVA VTFVPVSKV+GQ EV+DILAAVRPTT LVTIMLANNETG++MP+ Sbjct: 136 IRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVIMPIS 195 Query: 208 EISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGA 267 EIS+RIKALNQ R A+GLP +LVHTDAAQALGK+RVDVEDLGVDFLTIVGHKFYGPRIGA Sbjct: 196 EISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGA 255 Query: 268 LYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVR 327 LY+RG+G+ TPLYPMLFGGGQERNFRPGTENTPMIAGLGKAA+LV++NCE YEAHMRD+R Sbjct: 256 LYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIR 315 Query: 328 DYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAA 387 DYLEERLEAEFG KRIHLNS+FPG +RLPNTCNFSI+G +L+G++VLAQC+ L+ASVGA+ Sbjct: 316 DYLEERLEAEFG-KRIHLNSRFPGVERLPNTCNFSIQGSQLRGYMVLAQCQTLLASVGAS 374 Query: 388 CHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLE 442 CHSDH D+PSPVLLS G+P DVARNA+RLSVGRSTTRAEVDL+VQDLKQAV QLE Sbjct: 375 CHSDHEDRPSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAVNQLE 429 >5WGB-A nrPDB Length = 426 Score = 214 bits (546), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 147/418 (35%), Positives = 220/418 (52%), Gaps = 39/418 (9%) Query: 30 RKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGG 88 R +YMD ATTPL+P V+ AM + +GNP S ++ G +++ + AR+ +A +IG Sbjct: 26 RPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGA 85 Query: 89 KPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSI 148 P++IIFTSG TESNN+ I V + + + K H IT+ EH + Sbjct: 86 DPREIIFTSGATESNNIAIKGVARFYRSR-----------------KKHLITTQTEHKCV 128 Query: 149 RLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPE 208 L E + VT++PV K SG ++ ++ AA++P T LV++M NNE G+ P+ E Sbjct: 129 LDSCRSL-EAEGFQVTYLPVQK-SGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAE 186 Query: 209 ISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGA 267 I RI + + + HTDAAQA+GK +DV D+ +D ++I GHK YGP+ +GA Sbjct: 187 IG-RICSSRK---------VYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGA 236 Query: 268 LYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVR 327 +YIR + + GGGQER R GT TP++ GLG A E+ Q E Y+ H R + Sbjct: 237 IYIRRRPRVR-VEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEME-YD-HKRISK 293 Query: 328 DYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAA 387 L ERL + + P N S ++G +L + + S G+A Sbjct: 294 --LSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSF--AYVEGESLLMALKDVALSSGSA 349 Query: 388 CHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQA 445 C S +PS VL + G D+A +++R +GR TT EVD V+ Q V +L + + Sbjct: 350 CTSA-SLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMS 406 >4EB7-A nrPDB Length = 382 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 145/413 (35%), Positives = 218/413 (52%), Gaps = 46/413 (11%) Query: 33 YMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQD 92 Y DY + P++ +++AM M E++GNPSS +S G KA++ + ARE +AK++ G Sbjct: 3 YFDYTSAKPVDERILEAMLPYMTESFGNPSSVHSYGFKAREAVQEAREKVAKLVNGGGGT 62 Query: 93 IIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPL 152 ++FTSG TE+NNL I + KG H + S+VEH S+ P Sbjct: 63 VVFTSGATEANNLAIIG----YAMRNARKG-------------KHILVSAVEHMSVINPA 105 Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR 212 + L ++Q V ++PV K G+ +V I +R T LV++ ANNE G + PV EIS+ Sbjct: 106 KFL-QKQGFEVEYIPVGKY-GEVDVSFIDQKLRDDTILVSVQHANNEIGTIQPVEEISE- 162 Query: 213 IKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALYIR 271 V AG + H DA ++G+ VDVE +G D LTI + YGP+ +GAL+IR Sbjct: 163 --------VLAGKAAL--HIDATASVGQIEVDVEKIGADMLTISSNDIYGPKGVGALWIR 212 Query: 272 GLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNC-EAYEAHMRDVRDYL 330 + L P++ GGGQE R G+EN P I G GKAAE+ E E R + Sbjct: 213 ---KEAKLQPVILGGGQENGLRSGSENVPSIVGFGKAAEITAMEWREEAERLRRLRDRII 269 Query: 331 EERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRV--LMASVGAAC 388 + L+ E +LN P +RLPN N +R ++G ++ + + AS G+AC Sbjct: 270 DNVLKIE----ESYLNGH-P-EKRLPNNVN--VRFSYIEGESIVLSLDMAGIQASTGSAC 321 Query: 389 HSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQL 441 S QPS VL++ G+ + A L L++GR T +VD +++ L + +L Sbjct: 322 -SSKTLQPSHVLMACGLKHEEAHGTLLLTLGRYNTDEDVDRLLEVLPGVIERL 373 >5WT2-A nrPDB Length = 401 Score = 199 bits (505), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 143/423 (33%), Positives = 221/423 (52%), Gaps = 52/423 (12%) Query: 30 RKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGK 89 +++Y+D NATT ++P+V + M + + +GNPSS + G + I A + L K I + Sbjct: 3 QRIYLDNNATTRIDPKVKEIMDPFLRDHYGNPSSLHQFGTETHPAIAEALDKLYKGINAR 62 Query: 90 P-QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSI 148 D+I TS TESNN V+ V +F +K K H +T+ EH ++ Sbjct: 63 DIDDVIITSCATESNNWVLKGV--YFD-------------ECLKKGKNHIVTTVAEHPAV 107 Query: 149 RLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPE 208 R L E VT++P+++ G + + A+ T LV++M ANNETG++ P+ E Sbjct: 108 RSTCNFL-ESLGVEVTYLPINE-HGSITAEQVREAITEKTALVSVMWANNETGLIFPIEE 165 Query: 209 ISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGA 267 I A+ +E+ +L HTDA QA+GK VDV DFL+ HKF+GP+ IG Sbjct: 166 IG----AICKEK------GVLFHTDAVQAIGKIPVDVLKANADFLSFSAHKFHGPKGIGG 215 Query: 268 LYIR-GLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDV 326 LYIR G+G L P+ GG R GT N P I G+G+A +L ++ + + + + Sbjct: 216 LYIRSGVG----LTPLFHGGEHMNGRRSGTLNVPYIVGMGEAMKLAVEHLDYEKEVVGKL 271 Query: 327 RDYLEERL----EAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRV--L 380 RD LEE L + RIH R+PNT S+RG ++G +L + Sbjct: 272 RDKLEEALLKIPDVMVVGDRIH---------RVPNTTLVSVRG--IEGEAMLWDLNRSNI 320 Query: 381 MASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQ 440 AS G+AC S+ + +PV+++ G ++A A+RLS+ R T AE+D ++ QA + Sbjct: 321 AASTGSACASEDL-EANPVMVAIGASKELAHTAIRLSLSRFNTEAEIDKTIEVFSQAAVR 379 Query: 441 LED 443 L + Sbjct: 380 LRN 382 >1ECX-A nrPDB Length = 384 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 131/418 (31%), Positives = 214/418 (51%), Gaps = 48/418 (11%) Query: 31 KVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKP 90 +VY D NATT ++ V++ M E +GNP+S + G +A + ARE +AK++G P Sbjct: 2 RVYFDNNATTRVDDRVLEEMIVFYREKYGNPNSAHGMGIEANLHMEKAREKVAKVLGVSP 61 Query: 91 QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRL 150 +I FTS TES N ++ +V + F + + IT+ +EH ++ Sbjct: 62 SEIFFTSCATESINWILKTVAETFEKRKRT-----------------IITTPIEHKAVLE 104 Query: 151 PLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEIS 210 +++L + V +VPV G +++++ V T LV+IM ANNE G + PV +++ Sbjct: 105 TMKYLSMKGF-KVKYVPVDS-RGVVKLEELEKLVDEDTFLVSIMAANNEVGTIQPVEDVT 162 Query: 211 QRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALY 269 + +K N+E LVH DA Q +GK +E L VD+ + HKF+GP+ +G Y Sbjct: 163 RIVKKKNKE--------TLVHVDAVQTIGKIPFSLEKLEVDYASFSAHKFHGPKGVGITY 214 Query: 270 IRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDY 329 IR + P+ P++ GGGQER R GT+N P I G +A E+ + HM Sbjct: 215 IR---KGVPIRPLIHGGGQERGLRSGTQNVPGIVGAARAMEIAVEELSEAAKHM------ 265 Query: 330 LEERLEAEFGQKRIHLNSQF--PGTQRLPNTCNFS---IRGPRLQGHVVLAQCRVLMASV 384 E+L ++ ++L + P LPNT + S IRG LQ L + S Sbjct: 266 --EKLRSKLVSGLMNLGAHIITPLEISLPNTLSVSFPNIRGSTLQN---LLSGYGIYVST 320 Query: 385 GAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLE 442 +AC S ++ VL + GV +A+ A+R+S+ + T EVD ++ +++ ++ L+ Sbjct: 321 SSACTSKD-ERLRHVLDAMGVDRRIAQGAIRISLCKYNTEEEVDYFLKKIEEILSFLD 377 >3LVM-A nrPDB Length = 423 Score = 187 bits (476), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 128/425 (30%), Positives = 215/425 (50%), Gaps = 42/425 (9%) Query: 23 GKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWE--AWGNPSS-PYSAGRKAKDIINAAR 79 G + + + +Y+DY+ATTP++P V + M + M +GNP+S + G +A++ ++ AR Sbjct: 15 GVYRAMKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIAR 74 Query: 80 ESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFI 139 +A ++G P++I+FTSG TES+NL I + KG H I Sbjct: 75 NQIADLVGADPREIVFTSGATESDNLAIKGAANFYQ----KKG-------------KHII 117 Query: 140 TSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNE 199 TS EH ++ L E P + +G ++ ++ AA+R T LV+IM NNE Sbjct: 118 TSKTEHKAVLDTCRQLEREGFEVTYLAP--QRNGIIDLKELEAAMRDDTILVSIMHVNNE 175 Query: 200 TGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHK 259 G+V + I + +A I+ H DA Q++GK +D+ L VD ++ GHK Sbjct: 176 IGVVQDIAAIGEMCRARG----------IIYHVDATQSVGKLPIDLSQLKVDLMSFSGHK 225 Query: 260 FYGPR-IGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEA 318 YGP+ IGALY+R + + GGG ER R GT I G+G+A + + Sbjct: 226 IYGPKGIGALYVRRKPR-VRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMAT 284 Query: 319 YEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCR 378 +R +R+ L ++ + ++LN PN N S ++G ++ + Sbjct: 285 EMERLRGLRNRLWNGIK---DIEEVYLNGDLE--HGAPNILNVSFN--YVEGESLIMALK 337 Query: 379 VLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAV 438 L S G+AC S +PS VL + G+ ++A +++R S+GR TT E+D ++ +++++ Sbjct: 338 DLAVSSGSACTS-ASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSI 396 Query: 439 AQLED 443 +L D Sbjct: 397 GRLRD 401 >4ISY-A nrPDB Length = 404 Score = 183 bits (464), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 134/405 (33%), Positives = 216/405 (53%), Gaps = 36/405 (8%) Query: 33 YMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQD 92 Y+D+ ATTP+ P I+AM A+ GN SS +++GR A+ I ARE +A +G +P + Sbjct: 14 YLDHAATTPMHPAAIEAMA-AVQRTIGNASSLHTSGRSARRRIEEARELIADKLGARPSE 72 Query: 93 IIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPL 152 +IFT+GGTES+NL + + + A + ++ H + +T+ VEH ++ + Sbjct: 73 VIFTAGGTESDNLAVKGI---YWARRDAEPH-----------RRRIVTTEVEHHAVLDSV 118 Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRP--TTRLVTIMLANNETGIVMPVPEIS 210 LVE + A VT++P + G + A++ LV++M ANNE G ++P+ E+S Sbjct: 119 NWLVEHEGAHVTWLP-TAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMS 177 Query: 211 QRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYG-PRIGALY 269 + A+ G+P +H+DA QA+G+ +D G+ +++ GHKF G P +GAL Sbjct: 178 --VVAMEF-----GVP---MHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALL 227 Query: 270 IRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDY 329 +R P++ GGGQER+ R GT + G+ AA++ E A +R +RD Sbjct: 228 LR---RDVTCVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARLRLLRDR 284 Query: 330 LEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACH 389 L E + AE + LN RL +F+ RG ++L + S G+AC Sbjct: 285 LVEGVLAEI--DDVCLNGA-DDPMRLAGNAHFTFRGCEGDALLMLLDANGIECSTGSACT 341 Query: 390 SDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDL 434 + QPS VL++ GV AR +LRLS+G ++ A+VD ++ L Sbjct: 342 AGVA-QPSHVLIAMGVDAASARGSLRLSLGHTSVEADVDAALEVL 385 >4W91-A nrPDB Length = 422 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 119/427 (27%), Positives = 174/427 (40%), Gaps = 71/427 (16%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMI-GGK 89 VY+D A+ VI A+T A + N + A D +RE++ + + G Sbjct: 41 VYLDNGASAQKPQSVIDAVTHAYANEYANVHRGLHFLSNAATDAYEKSRETVRRFLNAGS 100 Query: 90 PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIR 149 +I+FT TE+ N V + G+ P G + S +EH S Sbjct: 101 VDEIVFTKNATEAINTVAY-----------------GYGMPFIGEGDEILLSIMEHHSNI 143 Query: 150 LPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEI 209 +P + E Q A + F PV +G +++ + T+LV I +N G V+P+ +I Sbjct: 144 VPWHFIRERQGAKLVFTPVDD-NGVFHIEEFEKRLSERTKLVAITHMSNTLGTVVPIKKI 202 Query: 210 SQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGAL 268 + A G+P ++ D +Q VDV+DLG D+ GHK YGP IG L Sbjct: 203 VELAHA-------RGIPVLV---DGSQGAVHLPVDVQDLGCDWYVFTGHKVYGPSGIGVL 252 Query: 269 YIRG--LGEFTPLYPMLFGGGQ------ERN---------FRPGTENTPMIAGLGKAAEL 311 Y R L + P GGG+ E N F GT GLG A E Sbjct: 253 YGRAQMLEKMRPFQ----GGGEMIEEVTEENVTYNHPPHRFEAGTPPIVQAIGLGAALEY 308 Query: 312 VTQ-NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQG 370 + + A AH D+RDY ERL RI N+ G +F++ G + Sbjct: 309 MEKIGRHAILAHEADLRDYAHERL-GRINSLRIFGNAPDKGA-----IISFALEG--IHA 360 Query: 371 HVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLV 430 H V +V A H P+L +GV + R S TRAEVD + Sbjct: 361 HDVSMVIDRAGVAVRAGTHC-----AQPLLKRFGVT-----STCRASFALYNTRAEVDAL 410 Query: 431 VQDLKQA 437 + L++A Sbjct: 411 AEALEKA 417 >5VPR-A nrPDB Length = 414 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 94/436 (21%), Positives = 181/436 (41%), Gaps = 80/436 (18%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNP--SSPYSAGRKAKDIINAARESLAKMIGGK 89 VY+D NA T +P+++ +E + ++ + A +++ AR+ + + I K Sbjct: 32 VYLD-NAATSQKPKMVLDAINNYYEHYNANVHRGIHTLSQVATEMMEDARKKVQRFINAK 90 Query: 90 -PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSI 148 +++FT G TE NLV +++ + + I S +EH S Sbjct: 91 HDYEVLFTKGTTEGINLVAYAM------------------TDLIKKDDEIIISYLEHHSN 132 Query: 149 RLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPE 208 +P + L + A + +P+++ G ++D + + T+LV++ +N GIV P+ E Sbjct: 133 IVPWQMLCQRTGAKLRVIPMNE-DGTLQIDVLDEWLSEKTKLVSVNQVSNALGIVNPIDE 191 Query: 209 ISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGA 267 I ++++A + + D AQA +DV+ + DF GHK YGP G Sbjct: 192 IIRKVRAKSNA---------FIFIDGAQAAPHFEIDVQTMDCDFFAFSGHKMYGPTGTGI 242 Query: 268 LYIRG--LGEFTPLYPMLFGGGQERN---------------FRPGTENTPMIAGLGKAAE 310 LY + L + P + GGG+ + F GT N +G A + Sbjct: 243 LYGKASVLEQLNPFH----GGGEMIDHCTFEKTTYAGLPFRFEAGTPNIAGNIAIGTAVD 298 Query: 311 LVTQ----NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFS-IRG 365 + + N A+E + E+ Q+++ + G + N + + Sbjct: 299 FMEKVGRSNIAAHEHAL------------LEYAQRKL---LEIEGLKVYGEKANRAGVVS 343 Query: 366 PRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRA 425 L G + + +++ +G A + H P++ +GV +R S T Sbjct: 344 FNLSGIGIASDVGMILDKLGIAVRTGH-HCTQPIMEYFGVA-----GTVRASFAVYNTFE 397 Query: 426 EVDLVVQDLKQAVAQL 441 E+D++ + +K+A L Sbjct: 398 EIDILTEGVKKAQKML 413 >5XT5-A nrPDB Length = 419 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 70/260 (26%), Positives = 116/260 (44%), Gaps = 36/260 (13%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGGKP 90 VY+D AT+ VI+ + K + N ++ G +A D ARE + K I K Sbjct: 26 VYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKS 85 Query: 91 Q-DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKP--HFITSSVEHDS 147 +IIFT G T S N+V S + AN KP + + +EH + Sbjct: 86 MAEIIFTKGTTTSLNMVALSYAR---AN----------------LKPGDEVVITYMEHHA 126 Query: 148 IRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVP 207 +P + V+ A + ++P+ + G ++D+ V T++V + +N G V P+ Sbjct: 127 NIIPWQQAVKATGATLKYIPLQE-DGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIK 185 Query: 208 EISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IG 266 E++ ++A ++V D AQ+ ++DV+DL DF + HK GP +G Sbjct: 186 EMA---------KIAHDNGAVIV-VDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVG 235 Query: 267 ALYIRGLGEFTPLYPMLFGG 286 LY + + P FGG Sbjct: 236 VLYGKK-ALLENMEPAEFGG 254 >6C9E-A nrPDB Length = 422 Score = 71.6 bits (174), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 73/265 (27%), Positives = 118/265 (44%), Gaps = 37/265 (13%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGGK- 89 VY D ATT VI A+ + + N ++ +A ++ AAR + + I + Sbjct: 41 VYFDNAATTQKPKAVIDAIAQFYEKDNSNVHRGVHALSVRATEMYEAARAKVKRFINARS 100 Query: 90 PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIR 149 P++ IF G TE+ NLV S+V +P + + +EH S Sbjct: 101 PRECIFVRGTTEAINLVAQSLV-----------------APRILPDEEILITHMEHHSNI 143 Query: 150 LPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEI 209 +P + + ++ + P+S ++G+ +++ + T++V I A+N G + PV + Sbjct: 144 VPWQMVCKKMGCKLQVAPIS-LNGEVILEEFERKLNENTKMVAINYASNSLGTINPVKTM 202 Query: 210 SQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGAL 268 IK ++ G +L D AQA VDV+DL DF GHK YGP IG L Sbjct: 203 ---IKMAHE----VGAKVLL---DGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTGIGVL 252 Query: 269 YIRG--LGEFTPLYPMLFGGGQERN 291 + + L TP GGG+ N Sbjct: 253 WGKEELLNSMTPYQ----GGGEMIN 273 >1T3I-A nrPDB Length = 420 Score = 71.2 bits (173), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 112/440 (25%), Positives = 178/440 (40%), Gaps = 82/440 (18%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGR-----KAKDIINAARESLAKMI 86 VY+D NA T +P +A+ + + + N ++ G +A D A R +AK I Sbjct: 30 VYLD-NAATSQKP---RAVLEKLMHYYENDNANVHRGAHQLSVRATDAYEAVRNKVAKFI 85 Query: 87 GGK-PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEH 145 + P++I++T TE+ NLV +S + N G IT+ +EH Sbjct: 86 NARSPREIVYTRNATEAINLVAYS----WGMNNLKAG-------------DEIITTVMEH 128 Query: 146 DSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMP 205 S +P + + + A + FV + + +++ + T+LVT++ +N G V P Sbjct: 129 HSNLVPWQMVAAKTGAVLKFVQLDE-QESFDLEHFKTLLSEKTKLVTVVHISNTLGCVNP 187 Query: 206 VPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR- 264 EI+Q AG +LV DA Q+ +DV+ + D+L GHK P Sbjct: 188 AEEIAQLAH-------QAG-AKVLV--DACQSAPHYPLDVQLIDCDWLVASGHKMCAPTG 237 Query: 265 IGALYIRGLGEFTPLYPMLFGGGQE---------------RNFRPGTENTPMIAGLGKAA 309 IG LY G E P FGGG+ F GT LG A Sbjct: 238 IGFLY--GKEEILEAMPPFFGGGEMIAEVFFDHFTTGELPHKFEAGTPAIAEAIALGAAV 295 Query: 310 ELVT----QNCEAYEAHMRDVRDYLEERLEAEFGQ-KRIHLNSQFPGTQRLPNTCNFSIR 364 + +T +N YE ++ YL + L GQ ++ L P +F++ Sbjct: 296 DYLTDLGMENIHNYEV---ELTHYLWQGL----GQIPQLRLYGPNPKHGDRAALASFNVA 348 Query: 365 GPRLQGHVVLAQCRVLMASVGAACHS-DHGDQPSPVLLSYGVPFDVARNALRLSVGRSTT 423 G + ++ G A S H QP L FD + +A R S+ T Sbjct: 349 GLH------ASDVATMVDQDGIAIRSGHHCTQPLHRL------FDASGSA-RASLYFYNT 395 Query: 424 RAEVDLVVQDLKQAVAQLED 443 + E+DL +Q L+ + D Sbjct: 396 KEEIDLFLQSLQATIRFFSD 415 >4LW2-A nrPDB Length = 404 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 109/434 (25%), Positives = 173/434 (39%), Gaps = 75/434 (17%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWE-AWGNP-SSPYSAGRKAKDIINAARESLAKMIGGK 89 VY+D +A T L+PE + T+ + + GN S ++ ++ AARE +A+++ Sbjct: 24 VYLD-SAATALKPEAVVEATQQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNA- 81 Query: 90 PQD--IIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDS 147 P D I++T G TES N+V + P I S EH + Sbjct: 82 PDDKTIVWTRGTTESINMVAQCYAR-----------------PRLQPGDEIIVSVAEHHA 124 Query: 148 IRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVP 207 +P + ++ A V +P++ +VD + + P +R++ + +N TG P Sbjct: 125 NLVPWLMVAQQTGAKVVKLPLN-AQRLPDVDLLPELITPRSRILALGQMSNVTG---GCP 180 Query: 208 EISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IG 266 ++++ I + +AG+ +V D AQ DV+ L +DF GHK YGP IG Sbjct: 181 DLARAITFAH----SAGM---VVMVDGAQGAVHFPADVQQLDIDFYAFSGHKLYGPTGIG 233 Query: 267 ALYIRGLGEFTPLYPMLFGGGQ---ERNF------------RPGTENTPMIAGLGKAAE- 310 LY G E GGG+ E +F GT N + GL A E Sbjct: 234 VLY--GKSELLEAMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEW 291 Query: 311 LVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQG 370 L + E+ R + E+ L G + + F G Sbjct: 292 LADYDINQAESWSRSLATLAEDALAKRPGFRSFRCQDS--------SLLAFDFAGVHHSD 343 Query: 371 HVVLAQCRVLMASVGAACHS-DHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDL 429 V L+A G A + H Q P+L GV LR S T+++VD Sbjct: 344 MV------TLLAEYGIALRAGQHCAQ--PLLAELGV-----TGTLRASFAPYNTKSDVDA 390 Query: 430 VVQDLKQAVAQLED 443 +V + +A+ L D Sbjct: 391 LVNAVDRALELLVD 404 >6MRE-A nrPDB Length = 420 Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 74/269 (27%), Positives = 109/269 (40%), Gaps = 58/269 (21%) Query: 91 QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRL 150 ++++F +G TE NLV +S N + A + I S +EH + + Sbjct: 100 EELVFVAGTTEGINLVANS-----WGNSNVR------------AGDNIIISQMEHHANIV 142 Query: 151 PLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEIS 210 P + L A + +P++ G +++ + TRL+ I +N G P+ E+ Sbjct: 143 PWQMLCARVGAELRVIPLNP-DGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEM- 200 Query: 211 QRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALY 269 I +Q V D AQA+ VDV+ L DF GHK YGP IG LY Sbjct: 201 --ITLAHQHGAK-------VLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILY 251 Query: 270 IRG--LGEFTPLYPMLFGGGQE----------------RNFRPGTENTPMIAGLGKAAEL 311 ++ L E P GGG F GT NT I GLG A E Sbjct: 252 VKEALLQEMPPWE----GGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEY 307 Query: 312 VT----QNCEAYEAHMRDVRDYLEERLEA 336 V+ N YE +++ Y +LE+ Sbjct: 308 VSALGLNNIAEYE---QNLMHYALSQLES 333 >4Q75-A nrPDB Length = 429 Score = 61.2 bits (147), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 68/265 (25%), Positives = 113/265 (42%), Gaps = 39/265 (14%) Query: 30 RKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP--SSPYSAGRKAKDIINAARESLAKMIG 87 + VY+D AT+ V+ A+ + +E + + + KA D AR+ +A+ I Sbjct: 38 KLVYLDSAATSQKPAAVLDAL-QNYYEFYNSNVHRGIHYLSAKATDEFELARKKVARFIN 96 Query: 88 GK-PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKP--HFITSSVE 144 ++I+FT TE+ NLV +S + KP I + E Sbjct: 97 ASDSREIVFTRNATEAINLVAYS-------------------WGLSNLKPGDEVILTVAE 137 Query: 145 HDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVM 204 H S +P + + ++ A + FV +++ +++ + + P T+LV + +N + Sbjct: 138 HHSCIVPWQIVSQKTGAVLKFVTLNE-DEVPDINKLRELISPKTKLVAVHHVSNVLASSL 196 Query: 205 PVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR 264 P+ EI + V A V DA Q++ VDV+ L DFL HK GP Sbjct: 197 PIEEI-----VVWAHDVGAK-----VLVDACQSVPHMVVDVQKLNADFLVASSHKMCGPT 246 Query: 265 -IGALYIRGLGEFTPLYPMLFGGGQ 288 IG LY G + P GGG+ Sbjct: 247 GIGFLY--GKSDLLHSMPPFLGGGE 269 >5HH9-A nrPDB Length = 390 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 60/210 (28%), Positives = 93/210 (44%), Gaps = 18/210 (8%) Query: 139 ITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDIL----AAVRPTTRLVTIM 194 +TSS EH S LE+ + V P+ K + D+IL A +RP TR++ + Sbjct: 105 LTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMT 164 Query: 195 LANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLT 254 + +G+ +P+ EI + ++ LNQ+R I+ D G + V D D+ Sbjct: 165 WVQSGSGVKLPIREIGKLVRELNQKRDEQD--RIIYVVDGVHGFGVEDVSFADFDCDYFI 222 Query: 255 IVGHKF-YGPR-IGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTP-------MIAGL 305 HK+ +GPR G + R L P + + NF GT TP L Sbjct: 223 AGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNF--GTLMTPGGYHAFEHRLAL 280 Query: 306 GKAAELVTQNCEA-YEAHMRDVRDYLEERL 334 G A EL Q +A +A + + YL++RL Sbjct: 281 GTAFELHLQLGKAEVQARIHQLNAYLKQRL 310 >3CAI-A nrPDB Length = 406 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/286 (19%), Positives = 112/286 (39%), Gaps = 39/286 (13%) Query: 67 AGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGG 126 + R++ +++AARE++A ++ P ++ + + V+ S++ +++ G+ Sbjct: 63 SARRSAAVLDAAREAVADLVNADPGGVVLGA-----DRAVLLSLLAEASSSRAGLGY--- 114 Query: 127 HHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRP 186 I S ++ ++ P A V + V +G+ + + Sbjct: 115 ----------EVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISK 164 Query: 187 TTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVE 246 +TRLV + N+ +G + V ++ K ++ V A LV D + A + +D+ Sbjct: 165 STRLVAV---NSASGTLGGVTDLRAMTKLVHD--VGA-----LVVVDHSAAAPYRLLDIR 214 Query: 247 DLGVDFLTIVGHKFYGPRIGALYIRG---LGEFTPLYPMLFGGGQERNFRPGTENTPMIA 303 + D +T+ H + GP IGA+ R + F + + G R G ++A Sbjct: 215 ETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATGPAR-LEIGVHQFGLLA 273 Query: 304 GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQF 349 G V + E A R ERL +LN F Sbjct: 274 G-------VVASIEYLAALDESARGSRRERLAVSMQSADAYLNRVF 312 >2DR1-A nrPDB Length = 386 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 44/178 (24%), Positives = 71/178 (39%), Gaps = 35/178 (19%) Query: 176 EVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAA 235 ++DD L P VTI TG++ P+PE+++ K ++ LV DA Sbjct: 136 DLDDALRK-NPDVEAVTITYNETSTGVLNPLPELAKVAKEHDK----------LVFVDAV 184 Query: 236 QALGKQRVDVEDLGVDFLTIVGHKFYGP----RIGALYIRGL---------GEF--TPLY 280 A+G + + G+D + K +G IGA R L G + PLY Sbjct: 185 SAMGGADIKFDKWGLDVVFSSSQKAFGVPPGLAIGAFSERFLEIAEKMPERGWYFDIPLY 244 Query: 281 PMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQN------CEAYEAHMRDVRDYLEE 332 +E+ P T P + G+ A ++ + E YE + VR+ + E Sbjct: 245 VKYL---KEKESTPSTPPMPQVFGINVALRIIEKMGGKEKWLEMYEKRAKMVREGVRE 299 >3OP7-A nrPDB Length = 375 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 59/130 (45%), Gaps = 27/130 (20%) Query: 77 AARESLAKMIGG-KPQDIIFTSGGTESNNLVIHSVVK-HFHANQTSKGHTGGHHSPVKGA 134 A ++S++++ G KP+ I+ T+G T +N LV++S+++ H + + P K Sbjct: 67 AFKKSVSQLYTGVKPEQILQTNGATGANLLVLYSLIEPGDHVISLYPTYQQLYDIP-KSL 125 Query: 135 KPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIM 194 +E ++ LP +++ + +RPTT+++ I Sbjct: 126 GAEVDLWQIEEENGWLP------------------------DLEKLRQLIRPTTKMICIN 161 Query: 195 LANNETGIVM 204 ANN TG VM Sbjct: 162 NANNPTGAVM 171 >2I3A-A nrPDB Length = 352 Score = 32.0 bits (71), Expect = 0.59, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 7/71 (9%) Query: 162 AVTFVPVSKVSG--QAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQE 219 AVT V VS SG +A D+L A ++ A N G+ PEI+Q ++A+ Sbjct: 179 AVTVVAVSGTSGAGRAATTDLLGA-----EVIGSARAYNIAGVHRHTPEIAQGLRAVTDR 233 Query: 220 RVAAGLPPILV 230 V+ P+L+ Sbjct: 234 DVSVSFTPVLI 244 >6AP7-A nrPDB Length = 269 Score = 32.0 bits (71), Expect = 0.63, Method: Compositional matrix adjust. Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 22/131 (16%) Query: 43 EPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTES 102 E E + + +A +EAW N +P + G D+ A RE + +P +F S + Sbjct: 141 EIEKVFSAMEANYEAWVNGFAPLAVG---ADVPAAVREFSRTLFNMRPDITLFVSRTVFN 197 Query: 103 NNL--VIHSVVKHFHANQTS-------------KGHTGG----HHSPVKGAKPHFITSSV 143 +++ V+ V H QT+ K H GG H ++G PH ++ Sbjct: 198 SDMRGVLGLVKVPCHIFQTARDHSVPASVATYLKNHLGGKNTVHWLNIEGHLPHLSAPTL 257 Query: 144 EHDSIRLPLEH 154 +R L H Sbjct: 258 LAQELRRALSH 268 >3J0C-A nrPDB Length = 442 Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Query: 276 FTPLYPMLFGGGQERNFRPGTENTPMI-AGLGKAAELVTQNCEAYEAHMRDVRDYLEERL 334 FT +YP ++GG TENT + A + K+ + + + EAY+AH V+ +L + Sbjct: 81 FTGVYPFMWGGAY---CFCDTENTQVSKAYVMKSDDCLADHAEAYKAHTASVQAFLNITV 137 Query: 335 EAEFGQKRIHLNSQFP 350 +++N + P Sbjct: 138 GEHSIVTTVYVNGETP 153 >1V2E-A nrPDB Length = 381 Score = 31.6 bits (70), Expect = 0.72, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 25/37 (67%) Query: 75 INAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVV 111 + A RE+LA+ +P+ ++ TSG TE+ +++ S+V Sbjct: 63 LPALREALAEEFAVEPESVVVTSGATEALYVLLQSLV 99 >4AOA-A nrPDB Length = 454 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 46/195 (23%), Positives = 80/195 (41%), Gaps = 37/195 (18%) Query: 41 PLEPEVIQAMTKAMWEAWGNPSSPYSA-------GRKAKDIINAARES------------ 81 P + + A+W+A G+ + + A G A +I +A E+ Sbjct: 68 PFPLTIARGEGAALWDADGHRYADFIAEYTAGVYGHSAPEIRDAVIEAMQGGINLTGHNL 127 Query: 82 ----LAKMIGGK-PQ--DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGA 134 LA++I + PQ + FT+ GTE+N + + + + HF + +GG+H V G Sbjct: 128 LEGRLARLICERFPQIEQLRFTNSGTEANLMALTAAL-HFTGRRKIVVFSGGYHGGVLGF 186 Query: 135 KPHFITSSVEHDSIRLPLEHL------VEE---QVAAVTFVPVSKVSGQAEVD-DILAAV 184 ++V D + LP +E ++A V P+ SG D L A+ Sbjct: 187 GARPSPTTVPFDFLVLPYNDAQTARAQIERHGPEIAVVLVEPMQGASGCIPGQPDFLQAL 246 Query: 185 RPTTRLVTIMLANNE 199 R + V +L +E Sbjct: 247 RESATQVGALLVFDE 261 >5W25-A nrPDB Length = 616 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 18/32 (56%) Query: 68 GRKAKDIINAARESLAKMIGGKPQDIIFTSGG 99 G AK++ A R LA +G KP D IF S G Sbjct: 380 GPVAKNLTEAERTGLADHVGAKPGDCIFFSAG 411 >3PRL-A nrPDB Length = 505 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 14/124 (11%) Query: 42 LEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTE 101 L P ++ +T AM AW P P + KD A SL+ Q IFT Sbjct: 368 LSPTLLDDVTPAMRVAWEEPFGPVLPIIRVKDANEAI--SLSNQSDYGLQASIFTKDTDR 425 Query: 102 SNNLVIHSVVKHFHANQTSKGHTGGHHSP----------VKGAKPHFITSSVEHDSIRLP 151 + N+ H V H N +K G H P V+G KP ++ + E ++ Sbjct: 426 AINIGKHLEVGTVHIN--AKTERGPDHFPFLGVKKSGLGVQGIKPSLLSMTRERVTVLNL 483 Query: 152 LEHL 155 E+L Sbjct: 484 AENL 487 >5DX5-A nrPDB Length = 400 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 137 HFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLA 196 H + S + L H + VTFV VS + D++ A++P T++V + Sbjct: 105 HVVASDTLYGCTFALLNHGLTRYGVEVTFVDVSNL------DEVKNALKPNTKVVYLETP 158 Query: 197 NNETGIVMPVPEISQRIKALNQE 219 N T V + +IS + N+E Sbjct: 159 ANPTLKVTDIRKISNMVHESNKE 181 >3QI6-A nrPDB Length = 392 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Query: 163 VTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQ 211 V + PV+ A++D + AA+RPTTRL+ + N + + I+Q Sbjct: 131 VEYTPVA----LADLDAVRAAIRPTTRLIWVETPTNPLLSIADIAGIAQ 175 >1YJS-A nrPDB Length = 419 Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 14/106 (13%) Query: 57 AWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKH--- 113 A G P Y G + DI+ AK + G + G ++N V +V++H Sbjct: 52 AEGYPGRRYYGGCEYVDIVEELARERAKQLFGAEHANVQPHSGAQANMAVYFTVLEHGDT 111 Query: 114 -FHANQTSKGHTGGHHSPVK--GAKPHFI-------TSSVEHDSIR 149 N + GH H SPV G + +F+ T +++D +R Sbjct: 112 VLGMNLSHGGHL-THGSPVNFSGVQYNFVAYGVDPETHVIDYDDVR 156 >4CVQ-A nrPDB Length = 431 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 6/43 (13%) Query: 176 EVDDILAAVRPTTRLVTIMLANNETG------IVMPVPEISQR 212 ++DDI A + P TR + I+ NN TG ++M + EI+++ Sbjct: 183 DLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQ 225 >4EGJ-A nrPDB Length = 334 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Query: 51 TKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSV 110 TK +W+ G P+ P+ A + D A+E +AK+ G P +F +E +++ + V Sbjct: 128 TKLVWQQLGIPTPPFEAVLRGDDYEARAKEIVAKL--GLP---LFVKPASEGSSVAVIKV 182 >2E7J-A nrPDB Length = 371 Score = 28.1 bits (61), Expect = 8.2, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 31/54 (57%), Gaps = 7/54 (12%) Query: 206 VPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHK 259 +P++ + K ++ V P+LV + A A+G+ V ++++G DF+ GHK Sbjct: 163 LPDVKKIAKVCSEYDV-----PLLV--NGAYAIGRMPVSLKEIGADFIVGSGHK 209 >5O5C-A nrPDB Length = 519 Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 92 DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHS-PVKGAKPHFITSSVEHDSIR 149 D IFTSGGT+S NL+ + + GH H P AK TS + H SI+ Sbjct: 163 DGIFTSGGTQS-NLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSHFSIQ 220 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3GZD-A nrPDB 605 e-173 3A9Z-A nrPDB 534 e-152 3LVM-A nrPDB 421 e-118 5WGB-A nrPDB 413 e-116 1ECX-A nrPDB 394 e-110 5WT2-A nrPDB 384 e-107 4EB7-A nrPDB 366 e-101 1T3I-A nrPDB 354 6e-98 5VPR-A nrPDB 353 7e-98 4W91-A nrPDB 344 3e-95 4ISY-A nrPDB 336 9e-93 5XT5-A nrPDB 326 9e-90 4LW2-A nrPDB 321 3e-88 4Q75-A nrPDB 313 8e-86 6C9E-A nrPDB 311 3e-85 6MRE-A nrPDB 299 1e-81 3CAI-A nrPDB 216 2e-56 5HH9-A nrPDB 200 8e-52 Sequences not found previously or not previously below threshold: 1QZ9-A nrPDB 83 3e-16 5DX5-A nrPDB 67 2e-11 5V1X-E nrPDB 64 1e-10 2DR1-A nrPDB 59 3e-09 1XI9-A nrPDB 58 1e-08 3OP7-A nrPDB 57 2e-08 4Q6R-A nrPDB 57 2e-08 3ZRR-A nrPDB 56 3e-08 1V2E-A nrPDB 56 3e-08 5K1R-A nrPDB 56 4e-08 2BKW-A nrPDB 56 5e-08 4W8I-A nrPDB 55 8e-08 1M32-A nrPDB 53 2e-07 2E7J-A nrPDB 53 3e-07 5O5C-A nrPDB 53 3e-07 3HBX-A nrPDB 49 3e-06 3DR4-A nrPDB 49 4e-06 1IBJ-A nrPDB 49 5e-06 3F9T-A nrPDB 49 5e-06 1O4S-A nrPDB 47 2e-05 5GP4-C nrPDB 46 2e-05 3KGX-A nrPDB 46 4e-05 2YRI-A nrPDB 45 7e-05 3WKR-A nrPDB 44 1e-04 3FFH-A nrPDB 44 2e-04 1J32-A nrPDB 43 3e-04 5LUC-A nrPDB 43 4e-04 1U08-A nrPDB 42 5e-04 2GB3-A nrPDB 42 7e-04 1N8P-A nrPDB 41 0.001 3QI6-A nrPDB 40 0.002 2Z9W-A nrPDB 39 0.006 2E54-A nrPDB 38 0.009 1GC4-A nrPDB 37 0.015 1PFF-A nrPDB 37 0.018 2O0R-A nrPDB 36 0.030 4PIW-A nrPDB 36 0.032 3RI6-A nrPDB 35 0.050 6F35-A nrPDB 35 0.069 3NYS-A nrPDB 34 0.086 4CVQ-A nrPDB 34 0.13 2QMA-A nrPDB 34 0.13 6BLG-A nrPDB 34 0.15 1MDZ-A nrPDB 34 0.16 2DGM-A nrPDB 34 0.17 3VOM-A nrPDB 33 0.35 5TSU-A nrPDB 32 0.44 5W25-A nrPDB 32 0.62 5DDW-A nrPDB 32 0.66 1ZEJ-A nrPDB 31 0.82 6G3D-A nrPDB 31 1.1 3TEJ-A nrPDB 31 1.1 2X98-A nrPDB 31 1.1 5K8B-A nrPDB 31 1.1 4EVZ-A nrPDB 31 1.2 5C2Z-A nrPDB 31 1.3 5TD7-A nrPDB 31 1.3 6F77-B nrPDB 31 1.4 3NRA-A nrPDB 31 1.6 2FMU-A nrPDB 30 1.7 2BKA-A nrPDB 30 1.9 1B9H-A nrPDB 29 4.3 4FAZ-A nrPDB 28 7.3 >3GZD-A nrPDB Length = 440 Score = 605 bits (1560), Expect = e-173, Method: Composition-based stats. Identities = 437/438 (99%), Positives = 437/438 (99%) Query: 8 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSA 67 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSA Sbjct: 3 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSA 62 Query: 68 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH 127 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH Sbjct: 63 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH 122 Query: 128 HSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPT 187 HSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQ EVDDILAAVRPT Sbjct: 123 HSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQTEVDDILAAVRPT 182 Query: 188 TRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVED 247 TRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVED Sbjct: 183 TRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVED 242 Query: 248 LGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK 307 LGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK Sbjct: 243 LGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK 302 Query: 308 AAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPR 367 AAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPR Sbjct: 303 AAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPR 362 Query: 368 LQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV 427 LQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV Sbjct: 363 LQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV 422 Query: 428 DLVVQDLKQAVAQLEDQA 445 DLVVQDLKQAVAQLEDQA Sbjct: 423 DLVVQDLKQAVAQLEDQA 440 >3A9Z-A nrPDB Length = 432 Score = 534 bits (1375), Expect = e-152, Method: Composition-based stats. Identities = 341/419 (81%), Positives = 380/419 (90%), Gaps = 1/419 (0%) Query: 24 KHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLA 83 + P RKVYMDYNATTPLEPEVIQA+T+AM EAWGNPSS Y AGRKAKDIIN AR SLA Sbjct: 12 VESPPNRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLA 71 Query: 84 KMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSV 143 KMIGGKPQDIIFTSGGTESNNLVIHS V+ FH QT +G T SP +G +PHFIT +V Sbjct: 72 KMIGGKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQGRTVDQISPEEGTRPHFITCTV 131 Query: 144 EHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIV 203 EHDSIRLPLEHLVE+QVA VTFVPVSKV+GQ EV+DILAAVRPTT LVTIMLANNETG++ Sbjct: 132 EHDSIRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVI 191 Query: 204 MPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGP 263 MP+ EIS+RIKALNQ R A+GLP +LVHTDAAQALGK+RVDVEDLGVDFLTIVGHKFYGP Sbjct: 192 MPISEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGP 251 Query: 264 RIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHM 323 RIGALY+RG+G+ TPLYPMLFGGGQERNFRPGTENTPMIAGLGKAA+LV++NCE YEAHM Sbjct: 252 RIGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHM 311 Query: 324 RDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMAS 383 RD+RDYLEERLEAEFG KRIHLNS+FPG +RLPNTCNFSI+G +L+G++VLAQC+ L+AS Sbjct: 312 RDIRDYLEERLEAEFG-KRIHLNSRFPGVERLPNTCNFSIQGSQLRGYMVLAQCQTLLAS 370 Query: 384 VGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLE 442 VGA+CHSDH D+PSPVLLS G+P DVARNA+RLSVGRSTTRAEVDL+VQDLKQAV QLE Sbjct: 371 VGASCHSDHEDRPSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAVNQLE 429 >3LVM-A nrPDB Length = 423 Score = 421 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 127/427 (29%), Positives = 218/427 (51%), Gaps = 42/427 (9%) Query: 23 GKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWE--AWGNPSS-PYSAGRKAKDIINAAR 79 G + + + +Y+DY+ATTP++P V + M + M +GNP+S + G +A++ ++ AR Sbjct: 15 GVYRAMKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIAR 74 Query: 80 ESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFI 139 +A ++G P++I+FTSG TES+NL I + H I Sbjct: 75 NQIADLVGADPREIVFTSGATESDNLAIKGAANFYQ-----------------KKGKHII 117 Query: 140 TSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNE 199 TS EH ++ L E + VT++ + +G ++ ++ AA+R T LV+IM NNE Sbjct: 118 TSKTEHKAVLDTCRQL-EREGFEVTYL-APQRNGIIDLKELEAAMRDDTILVSIMHVNNE 175 Query: 200 TGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHK 259 G+V + I + +A I+ H DA Q++GK +D+ L VD ++ GHK Sbjct: 176 IGVVQDIAAIGEMCRAR----------GIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHK 225 Query: 260 FYGPR-IGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEA 318 YGP+ IGALY+R + + GGG ER R GT I G+G+A + + Sbjct: 226 IYGPKGIGALYVRRKPR-VRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMAT 284 Query: 319 YEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCR 378 +R +R+ L ++ + ++LN PN N S ++G ++ + Sbjct: 285 EMERLRGLRNRLWNGIK---DIEEVYLNG--DLEHGAPNILNVSFN--YVEGESLIMALK 337 Query: 379 VLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAV 438 L S G+AC S +PS VL + G+ ++A +++R S+GR TT E+D ++ +++++ Sbjct: 338 DLAVSSGSACTSA-SLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSI 396 Query: 439 AQLEDQA 445 +L D + Sbjct: 397 GRLRDLS 403 >5WGB-A nrPDB Length = 426 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 142/420 (33%), Positives = 213/420 (50%), Gaps = 39/420 (9%) Query: 28 PERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMI 86 R +YMD ATTPL+P V+ AM + +GNP S ++ G +++ + AR+ +A +I Sbjct: 24 MLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLI 83 Query: 87 GGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHD 146 G P++IIFTSG TESNN+ I V + + + K H IT+ EH Sbjct: 84 GADPREIIFTSGATESNNIAIKGVARFYRSR-----------------KKHLITTQTEHK 126 Query: 147 SIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPV 206 + L E + VT++PV K SG ++ ++ AA++P T LV++M NNE G+ P+ Sbjct: 127 CVLDSCRSL-EAEGFQVTYLPVQK-SGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPI 184 Query: 207 PEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-I 265 EI + + + HTDAAQA+GK +DV D+ +D ++I GHK YGP+ + Sbjct: 185 AEIGRICSSR----------KVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGV 234 Query: 266 GALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRD 325 GA+YIR + + GGGQER R GT TP++ GLG A E+ Q E Sbjct: 235 GAIYIRRRPR-VRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEY----DHK 289 Query: 326 VRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVG 385 L ERL + + P N S ++G +L + + S G Sbjct: 290 RISKLSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFA--YVEGESLLMALKDVALSSG 347 Query: 386 AACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQA 445 +AC S +PS VL + G D+A +++R +GR TT EVD V+ Q V +L + + Sbjct: 348 SACTSA-SLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMS 406 >1ECX-A nrPDB Length = 384 Score = 394 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 128/415 (30%), Positives = 209/415 (50%), Gaps = 42/415 (10%) Query: 31 KVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKP 90 +VY D NATT ++ V++ M E +GNP+S + G +A + ARE +AK++G P Sbjct: 2 RVYFDNNATTRVDDRVLEEMIVFYREKYGNPNSAHGMGIEANLHMEKAREKVAKVLGVSP 61 Query: 91 QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRL 150 +I FTS TES N ++ +V + F + + IT+ +EH ++ Sbjct: 62 SEIFFTSCATESINWILKTVAETFEKRKRT-----------------IITTPIEHKAVLE 104 Query: 151 PLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEIS 210 +++L + V +VPV G +++++ V T LV+IM ANNE G + PV +++ Sbjct: 105 TMKYLSMK-GFKVKYVPVDSR-GVVKLEELEKLVDEDTFLVSIMAANNEVGTIQPVEDVT 162 Query: 211 QRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALY 269 + +K N+E LVH DA Q +GK +E L VD+ + HKF+GP+ +G Y Sbjct: 163 RIVKKKNKE--------TLVHVDAVQTIGKIPFSLEKLEVDYASFSAHKFHGPKGVGITY 214 Query: 270 IRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDY 329 IR + P+ P++ GGGQER R GT+N P I G +A E+ + HM +R Sbjct: 215 IR---KGVPIRPLIHGGGQERGLRSGTQNVPGIVGAARAMEIAVEELSEAAKHMEKLRSK 271 Query: 330 LEERLEAEFGQKRIHLNSQF--PGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAA 387 L L ++L + P LPNT + S R L + S +A Sbjct: 272 LVSGL--------MNLGAHIITPLEISLPNTLSVSFPNIRGSTLQNLLSGYGIYVSTSSA 323 Query: 388 CHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLE 442 C S ++ VL + GV +A+ A+R+S+ + T EVD ++ +++ ++ L+ Sbjct: 324 CTSKD-ERLRHVLDAMGVDRRIAQGAIRISLCKYNTEEEVDYFLKKIEEILSFLD 377 >5WT2-A nrPDB Length = 401 Score = 384 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 137/422 (32%), Positives = 211/422 (50%), Gaps = 42/422 (9%) Query: 28 PERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIG 87 +++Y+D NATT ++P+V + M + + +GNPSS + G + I A + L K I Sbjct: 1 MVQRIYLDNNATTRIDPKVKEIMDPFLRDHYGNPSSLHQFGTETHPAIAEALDKLYKGIN 60 Query: 88 GKP-QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHD 146 + D+I TS TESNN V+ V +K K H +T+ EH Sbjct: 61 ARDIDDVIITSCATESNNWVLKGV---------------YFDECLKKGKNHIVTTVAEHP 105 Query: 147 SIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPV 206 ++R L E VT++P+++ G + + A+ T LV++M ANNETG++ P+ Sbjct: 106 AVRSTCNFL-ESLGVEVTYLPINE-HGSITAEQVREAITEKTALVSVMWANNETGLIFPI 163 Query: 207 PEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-I 265 EI K +L HTDA QA+GK VDV DFL+ HKF+GP+ I Sbjct: 164 EEIGAICKEK----------GVLFHTDAVQAIGKIPVDVLKANADFLSFSAHKFHGPKGI 213 Query: 266 GALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRD 325 G LYIR L P+ GG R GT N P I G+G+A +L ++ + + + Sbjct: 214 GGLYIR---SGVGLTPLFHGGEHMNGRRSGTLNVPYIVGMGEAMKLAVEHLDYEKEVVGK 270 Query: 326 VRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRV--LMAS 383 +RD LEE L K + R+PNT S+RG ++G +L + AS Sbjct: 271 LRDKLEEALL-----KIPDVMVVGDRIHRVPNTTLVSVRG--IEGEAMLWDLNRSNIAAS 323 Query: 384 VGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLED 443 G+AC S+ + +PV+++ G ++A A+RLS+ R T AE+D ++ QA +L + Sbjct: 324 TGSACASED-LEANPVMVAIGASKELAHTAIRLSLSRFNTEAEIDKTIEVFSQAAVRLRN 382 Query: 444 QA 445 + Sbjct: 383 IS 384 >4EB7-A nrPDB Length = 382 Score = 366 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 143/415 (34%), Positives = 213/415 (51%), Gaps = 42/415 (10%) Query: 33 YMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQD 92 Y DY + P++ +++AM M E++GNPSS +S G KA++ + ARE +AK++ G Sbjct: 3 YFDYTSAKPVDERILEAMLPYMTESFGNPSSVHSYGFKAREAVQEAREKVAKLVNGGGGT 62 Query: 93 IIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPL 152 ++FTSG TE+NNL I + KG H + S+VEH S+ P Sbjct: 63 VVFTSGATEANNLAIIG----YAMRNARKG-------------KHILVSAVEHMSVINPA 105 Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR 212 + L ++Q V ++PV K G+ +V I +R T LV++ ANNE G + PV EIS+ Sbjct: 106 KFL-QKQGFEVEYIPVGKY-GEVDVSFIDQKLRDDTILVSVQHANNEIGTIQPVEEISE- 162 Query: 213 IKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALYIR 271 V AG + H DA ++G+ VDVE +G D LTI + YGP+ +GAL+IR Sbjct: 163 --------VLAGKAAL--HIDATASVGQIEVDVEKIGADMLTISSNDIYGPKGVGALWIR 212 Query: 272 GLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNC-EAYEAHMRDVRDYL 330 + L P++ GGGQE R G+EN P I G GKAAE+ E E R + Sbjct: 213 KEAK---LQPVILGGGQENGLRSGSENVPSIVGFGKAAEITAMEWREEAERLRRLRDRII 269 Query: 331 EERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHS 390 + L+ E +LN +RLPN N + V+ + AS G+AC S Sbjct: 270 DNVLKIE----ESYLNGH--PEKRLPNNVNVRFSYIEGESIVLSLDMAGIQASTGSAC-S 322 Query: 391 DHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQA 445 QPS VL++ G+ + A L L++GR T +VD +++ L + +L + Sbjct: 323 SKTLQPSHVLMACGLKHEEAHGTLLLTLGRYNTDEDVDRLLEVLPGVIERLRSMS 377 >1T3I-A nrPDB Length = 420 Score = 354 bits (907), Expect = 6e-98, Method: Composition-based stats. Identities = 100/433 (23%), Positives = 162/433 (37%), Gaps = 66/433 (15%) Query: 31 KVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGGK 89 VY+D AT+ V++ + N + +A D A R +AK I + Sbjct: 29 LVYLDNAATSQKPRAVLEKLMHYYENDNANVHRGAHQLSVRATDAYEAVRNKVAKFINAR 88 Query: 90 -PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSI 148 P++I++T TE+ NLV +S + N G IT+ +EH S Sbjct: 89 SPREIVYTRNATEAINLVAYS----WGMNNLKAG-------------DEIITTVMEHHSN 131 Query: 149 RLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPE 208 +P + + + A + FV + + +++ + T+LVT++ +N G V P E Sbjct: 132 LVPWQMVAAKTGAVLKFVQLDE-QESFDLEHFKTLLSEKTKLVTVVHISNTLGCVNPAEE 190 Query: 209 ISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGA 267 I+Q + V DA Q+ +DV+ + D+L GHK P IG Sbjct: 191 IAQLAHQAGAK----------VLVDACQSAPHYPLDVQLIDCDWLVASGHKMCAPTGIGF 240 Query: 268 LYIRGLGEFTPLYPMLFGGGQE---------------RNFRPGTENTPMIAGLGKAAELV 312 LY G E P FGGG+ F GT LG A + + Sbjct: 241 LY--GKEEILEAMPPFFGGGEMIAEVFFDHFTTGELPHKFEAGTPAIAEAIALGAAVDYL 298 Query: 313 TQ-NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGH 371 T E + ++ YL + L ++ L P +F++ G Sbjct: 299 TDLGMENIHNYEVELTHYLWQGLG---QIPQLRLYGPNPKHGDRAALASFNVAGLH---- 351 Query: 372 VVLAQCRVLMASVGAACHS-DHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLV 430 + ++ G A S H QP L A + R S+ T+ E+DL Sbjct: 352 --ASDVATMVDQDGIAIRSGHHCTQPLHRLF-------DASGSARASLYFYNTKEEIDLF 402 Query: 431 VQDLKQAVAQLED 443 +Q L+ + D Sbjct: 403 LQSLQATIRFFSD 415 >5VPR-A nrPDB Length = 414 Score = 353 bits (906), Expect = 7e-98, Method: Composition-based stats. Identities = 91/433 (21%), Positives = 172/433 (39%), Gaps = 68/433 (15%) Query: 29 ERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIG 87 + VY+D AT+ V+ A+ N ++ + A +++ AR+ + + I Sbjct: 29 KDLVYLDNAATSQKPKMVLDAINNYYEHYNANVHRGIHTLSQVATEMMEDARKKVQRFIN 88 Query: 88 GK-PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHD 146 K +++FT G TE NLV +++ + + I S +EH Sbjct: 89 AKHDYEVLFTKGTTEGINLVAYAM------------------TDLIKKDDEIIISYLEHH 130 Query: 147 SIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPV 206 S +P + L + A + +P+++ G ++D + + T+LV++ +N GIV P+ Sbjct: 131 SNIVPWQMLCQRTGAKLRVIPMNE-DGTLQIDVLDEWLSEKTKLVSVNQVSNALGIVNPI 189 Query: 207 PEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-I 265 EI ++++A + + D AQA +DV+ + DF GHK YGP Sbjct: 190 DEIIRKVRAKSNA---------FIFIDGAQAAPHFEIDVQTMDCDFFAFSGHKMYGPTGT 240 Query: 266 GALYIRGLGEFTPLYPMLFGGGQERN---------------FRPGTENTPMIAGLGKAAE 310 G LY + GGG+ + F GT N +G A + Sbjct: 241 GILYGKA--SVLEQLNPFHGGGEMIDHCTFEKTTYAGLPFRFEAGTPNIAGNIAIGTAVD 298 Query: 311 LVTQ-NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFS-IRGPRL 368 + + AH + +Y + +L + G + N + + L Sbjct: 299 FMEKVGRSNIAAHEHALLEYAQRKLL------------EIEGLKVYGEKANRAGVVSFNL 346 Query: 369 QGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVD 428 G + + +++ +G A + H P++ +GV +R S T E+D Sbjct: 347 SGIGIASDVGMILDKLGIAVRTGH-HCTQPIMEYFGVA-----GTVRASFAVYNTFEEID 400 Query: 429 LVVQDLKQAVAQL 441 ++ + +K+A L Sbjct: 401 ILTEGVKKAQKML 413 >4W91-A nrPDB Length = 422 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 110/432 (25%), Positives = 163/432 (37%), Gaps = 67/432 (15%) Query: 29 ERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIG 87 + VY+D A+ VI A+T A + N + A D +RE++ + + Sbjct: 38 KTLVYLDNGASAQKPQSVIDAVTHAYANEYANVHRGLHFLSNAATDAYEKSRETVRRFLN 97 Query: 88 GKP-QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHD 146 +I+FT TE+ N V + P G + S +EH Sbjct: 98 AGSVDEIVFTKNATEAINTVAYGY-----------------GMPFIGEGDEILLSIMEHH 140 Query: 147 SIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPV 206 S +P + E Q A + F PV +G +++ + T+LV I +N G V+P+ Sbjct: 141 SNIVPWHFIRERQGAKLVFTPVD-DNGVFHIEEFEKRLSERTKLVAITHMSNTLGTVVPI 199 Query: 207 PEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-I 265 +I + A I V D +Q VDV+DLG D+ GHK YGP I Sbjct: 200 KKIVELAHAR----------GIPVLVDGSQGAVHLPVDVQDLGCDWYVFTGHKVYGPSGI 249 Query: 266 GALYIRGLGEFTPLYPMLFGGGQE---------------RNFRPGTENTPMIAGLGKAAE 310 G LY R + GGG+ F GT GLG A E Sbjct: 250 GVLYGRA--QMLEKMRPFQGGGEMIEEVTEENVTYNHPPHRFEAGTPPIVQAIGLGAALE 307 Query: 311 LVTQ-NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQ 369 + + A AH D+RDY ERL RI N+ G +F++ G Sbjct: 308 YMEKIGRHAILAHEADLRDYAHERL-GRINSLRIFGNAPDKGA-----IISFALEGIHAH 361 Query: 370 GHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDL 429 ++ + G C P+L +GV + R S TRAEVD Sbjct: 362 DVSMVIDRAGVAVRAGTHC-------AQPLLKRFGVT-----STCRASFALYNTRAEVDA 409 Query: 430 VVQDLKQAVAQL 441 + + L++A Sbjct: 410 LAEALEKARKFF 421 >4ISY-A nrPDB Length = 404 Score = 336 bits (862), Expect = 9e-93, Method: Composition-based stats. Identities = 133/407 (32%), Positives = 213/407 (52%), Gaps = 36/407 (8%) Query: 33 YMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQD 92 Y+D+ ATTP+ P I+AM A+ GN SS +++GR A+ I ARE +A +G +P + Sbjct: 14 YLDHAATTPMHPAAIEAMA-AVQRTIGNASSLHTSGRSARRRIEEARELIADKLGARPSE 72 Query: 93 IIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPL 152 +IFT+GGTES+NL + + + A + ++ H + +T+ VEH ++ + Sbjct: 73 VIFTAGGTESDNLAVKGI---YWARRDAEPH-----------RRRIVTTEVEHHAVLDSV 118 Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVR--PTTRLVTIMLANNETGIVMPVPEIS 210 LVE + A VT++P + G + A++ LV++M ANNE G ++P+ E+S Sbjct: 119 NWLVEHEGAHVTWLP-TAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMS 177 Query: 211 QRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALY 269 V A + +H+DA QA+G+ +D G+ +++ GHKF GP +GAL Sbjct: 178 ----------VVAMEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALL 227 Query: 270 IRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDY 329 +R P++ GGGQER+ R GT + G+ AA++ E A +R +RD Sbjct: 228 LR---RDVTCVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARLRLLRDR 284 Query: 330 LEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACH 389 L E + AE + LN RL +F+ RG ++L + S G+AC Sbjct: 285 LVEGVLAEI--DDVCLNGA-DDPMRLAGNAHFTFRGCEGDALLMLLDANGIECSTGSACT 341 Query: 390 SDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQ 436 + QPS VL++ GV AR +LRLS+G ++ A+VD ++ L Sbjct: 342 AGVA-QPSHVLIAMGVDAASARGSLRLSLGHTSVEADVDAALEVLPG 387 >5XT5-A nrPDB Length = 419 Score = 326 bits (836), Expect = 9e-90, Method: Composition-based stats. Identities = 89/431 (20%), Positives = 157/431 (36%), Gaps = 66/431 (15%) Query: 31 KVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGGK 89 VY+D AT+ VI+ + K + N ++ G +A D ARE + K I K Sbjct: 25 LVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAK 84 Query: 90 PQ-DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSI 148 +IIFT G T S N+V S + + + +EH + Sbjct: 85 SMAEIIFTKGTTTSLNMVALSYAR-----------------ANLKPGDEVVITYMEHHAN 127 Query: 149 RLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPE 208 +P + V+ A + ++P+ + G ++D+ V T++V + +N G V P+ E Sbjct: 128 IIPWQQAVKATGATLKYIPLQE-DGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKE 186 Query: 209 ISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGA 267 +++ ++ D AQ+ ++DV+DL DF + HK GP +G Sbjct: 187 MAKIAH----------DNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGV 236 Query: 268 LYIRGLGEFTPLYPMLFGGGQE--------------RNFRPGTENTPMIAGLGKAAELVT 313 LY + + P FGG F GT GLG A + + Sbjct: 237 LYGK-KALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLE 295 Query: 314 Q-NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHV 372 + + H + Y ER + ++ G + F++ Sbjct: 296 EIGLDEISRHEHKLAAYALERFR-QLDGVTVY------GPEERAGLVTFNLDDVHPH--- 345 Query: 373 VLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQ 432 ++ + G A + H P++ V R S T E+D +V+ Sbjct: 346 ---DVATVLDAEGIAVRAGH-HCAQPLMKWLDVTA-----TARASFYLYNTEEEIDKLVE 396 Query: 433 DLKQAVAQLED 443 L++ + Sbjct: 397 ALQKTKEYFTN 407 >4LW2-A nrPDB Length = 404 Score = 321 bits (823), Expect = 3e-88, Method: Composition-based stats. Identities = 99/431 (22%), Positives = 160/431 (37%), Gaps = 69/431 (16%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGG-K 89 VY+D AT V++A + + GN S ++ ++ AARE +A+++ Sbjct: 24 VYLDSAATALKPEAVVEATQQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPD 83 Query: 90 PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIR 149 + I++T G TES N+V + P I S EH + Sbjct: 84 DKTIVWTRGTTESINMVAQCYAR-----------------PRLQPGDEIIVSVAEHHANL 126 Query: 150 LPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEI 209 +P + ++ A V +P++ +VD + + P +R++ + +N TG P++ Sbjct: 127 VPWLMVAQQTGAKVVKLPLN-AQRLPDVDLLPELITPRSRILALGQMSNVTG---GCPDL 182 Query: 210 SQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGAL 268 ++ I + ++V D AQ DV+ L +DF GHK YGP IG L Sbjct: 183 ARAITFAHS-------AGMVVMVDGAQGAVHFPADVQQLDIDFYAFSGHKLYGPTGIGVL 235 Query: 269 YIRGLGEFTPLYPMLFGGGQE---------------RNFRPGTENTPMIAGLGKAAE-LV 312 Y G E GGG+ GT N + GL A E L Sbjct: 236 Y--GKSELLEAMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEWLA 293 Query: 313 TQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHV 372 + E+ R + E+ L G + + F G V Sbjct: 294 DYDINQAESWSRSLATLAEDALAKRPGFRSFRCQDS--------SLLAFDFAGVHHSDMV 345 Query: 373 VLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQ 432 L+A G A + P+L GV LR S T+++VD +V Sbjct: 346 ------TLLAEYGIALRAGQ-HCAQPLLAELGVT-----GTLRASFAPYNTKSDVDALVN 393 Query: 433 DLKQAVAQLED 443 + +A+ L D Sbjct: 394 AVDRALELLVD 404 >4Q75-A nrPDB Length = 429 Score = 313 bits (802), Expect = 8e-86, Method: Composition-based stats. Identities = 96/435 (22%), Positives = 155/435 (35%), Gaps = 70/435 (16%) Query: 30 RKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGG 88 + VY+D AT+ V+ A+ N + KA D AR+ +A+ I Sbjct: 38 KLVYLDSAATSQKPAAVLDALQNYYEFYNSNVHRGIHYLSAKATDEFELARKKVARFINA 97 Query: 89 -KPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDS 147 ++I+FT TE+ NLV +S I + EH S Sbjct: 98 SDSREIVFTRNATEAINLVAYS-----------------WGLSNLKPGDEVILTVAEHHS 140 Query: 148 IRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVP 207 +P + + ++ A + FV +++ +++ + + P T+LV + +N +P+ Sbjct: 141 CIVPWQIVSQKTGAVLKFVTLNE-DEVPDINKLRELISPKTKLVAVHHVSNVLASSLPIE 199 Query: 208 EISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IG 266 EI + V A V DA Q++ VDV+ L DFL HK GP IG Sbjct: 200 EI-----VVWAHDVGAK-----VLVDACQSVPHMVVDVQKLNADFLVASSHKMCGPTGIG 249 Query: 267 ALYIRGLGEFTPLYPMLFGGGQERN---------------FRPGTENTPMIAGLGKAAEL 311 LY G + P GGG+ + F GT LG A + Sbjct: 250 FLY--GKSDLLHSMPPFLGGGEMISDVFLDHSTYAEPPSRFEAGTPAIGEAIALGAAVDY 307 Query: 312 VT----QNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQ-RLPNTCNFSIRGP 366 ++ YE + YL E+L + + + P C+F++ G Sbjct: 308 LSGIGMPKIHEYEVEIGK---YLYEKLSS---LPDVRIYGPRPSESVHRGALCSFNVEGL 361 Query: 367 RLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAE 426 G A S H P+ GV + R S+ T+ + Sbjct: 362 HPTDLATFLD-----QQHGVAIRSGH-HCAQPLHRYLGVNA-----SARASLYFYNTKDD 410 Query: 427 VDLVVQDLKQAVAQL 441 VD + L V+ Sbjct: 411 VDAFIVALADTVSFF 425 >6C9E-A nrPDB Length = 422 Score = 311 bits (797), Expect = 3e-85, Method: Composition-based stats. Identities = 97/430 (22%), Positives = 164/430 (38%), Gaps = 67/430 (15%) Query: 31 KVYMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGGK 89 VY D ATT VI A+ + + N ++ +A ++ AAR + + I + Sbjct: 40 LVYFDNAATTQKPKAVIDAIAQFYEKDNSNVHRGVHALSVRATEMYEAARAKVKRFINAR 99 Query: 90 -PQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSI 148 P++ IF G TE+ NLV S+V P + + +EH S Sbjct: 100 SPRECIFVRGTTEAINLVAQSLVA-----------------PRILPDEEILITHMEHHSN 142 Query: 149 RLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPE 208 +P + + ++ + P+S ++G+ +++ + T++V I A+N G + PV Sbjct: 143 IVPWQMVCKKMGCKLQVAPIS-LNGEVILEEFERKLNENTKMVAINYASNSLGTINPVKT 201 Query: 209 ISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGA 267 + + + + V D AQA VDV+DL DF GHK YGP IG Sbjct: 202 MIKMAHEVGAK----------VLLDGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTGIGV 251 Query: 268 LYIRGLGEFTPLYPMLFGGGQERN---------------FRPGTENTPMIAGLGKAAELV 312 L+ G E GGG+ N F GT N GL A + + Sbjct: 252 LW--GKEELLNSMTPYQGGGEMINSVSFEATEYAAIPHKFEAGTPNIAGAIGLAAAIDYI 309 Query: 313 -TQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGH 371 + + +A + + +Y + +EA G + N + G Sbjct: 310 WSLDLDAIAEYETQLLNYATKAIEA------------VKGYNIIGTAANKVPIISFVHGK 357 Query: 372 VVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVV 431 + ++ S G A S H P++ Y V R+S+ T E+D + Sbjct: 358 IHAHDIGTILDSEGIAIRSGH-HCTMPLMDFYDVAA-----TSRISMSFYNTFKEIDYCM 411 Query: 432 QDLKQAVAQL 441 + L++ Sbjct: 412 EALQRVKEVF 421 >6MRE-A nrPDB Length = 420 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 98/429 (22%), Positives = 159/429 (37%), Gaps = 69/429 (16%) Query: 33 YMDYNATTPLEPEVIQAMTKAMWEAWGNP-SSPYSAGRKAKDIINAARESLAKMIGGKP- 90 Y+D A+ +VI A + + ++ +A + + R+ + I + Sbjct: 40 YLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSA 99 Query: 91 QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRL 150 ++++F +G TE NLV +S N + A + I S +EH + + Sbjct: 100 EELVFVAGTTEGINLVANS-----WGNSNVR------------AGDNIIISQMEHHANIV 142 Query: 151 PLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEIS 210 P + L A + +P++ G +++ + TRL+ I +N G P+ E+ Sbjct: 143 PWQMLCARVGAELRVIPLNP-DGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEM- 200 Query: 211 QRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR-IGALY 269 I +Q V D AQA+ VDV+ L DF GHK YGP IG LY Sbjct: 201 --ITLAHQHGAK-------VLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILY 251 Query: 270 IRGLGEFTPLYPMLFGGGQE----------------RNFRPGTENTPMIAGLGKAAELVT 313 ++ P GGG F GT NT I GLG A E V+ Sbjct: 252 VK--EALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVS 309 Query: 314 Q-NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHV 372 + +++ Y +LE+ + L Q F++ G Sbjct: 310 ALGLNNIAEYEQNLMHYALSQLES---VPDLTLYGP----QNRLGVIAFNL------GKH 356 Query: 373 VLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQ 432 + + G A + H P++ Y VP R S+ T EVD +V Sbjct: 357 HAYDVGSFLDNYGIAVRTGH-HCAMPLMAYYNVPA-----MCRASLAMYNTHEEVDRLVT 410 Query: 433 DLKQAVAQL 441 L++ L Sbjct: 411 GLQRIHRLL 419 >3CAI-A nrPDB Length = 406 Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 76/423 (17%), Positives = 151/423 (35%), Gaps = 68/423 (16%) Query: 32 VYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQ 91 V+ D A + V ++ A + + + + R++ +++AARE++A ++ P Sbjct: 28 VHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPG 87 Query: 92 DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLP 151 ++ ++ V+ S++ +++ G+ I S ++ ++ P Sbjct: 88 GVVLG-----ADRAVLLSLLAEASSSRAGLGY-------------EVIVSRLDDEANIAP 129 Query: 152 LEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQ 211 A V + V +G+ + + +TRLV + N+ +G + V ++ Sbjct: 130 WLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRLVAV---NSASGTLGGVTDLRA 186 Query: 212 RIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIR 271 K ++ LV D + A + +D+ + D +T+ H + GP IGA+ R Sbjct: 187 MTKLVHDVGA-------LVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFR 239 Query: 272 G---LGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRD 328 + F + + G R G ++AG V + E A R Sbjct: 240 DPSVMNSFGSVSTNPYATGPAR-LEIGVHQFGLLAG-------VVASIEYLAALDESARG 291 Query: 329 YLEERLEAEFGQKRIHLNSQFP-----------------GTQRLPNTCNFSIRGPRLQGH 371 ERL +LN F ++P +F++ Sbjct: 292 SRRERLAVSMQSADAYLNRVFDYLMVSLRSLPLVMLIGRPEAQIP-VVSFAVHKVPADRV 350 Query: 372 VVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVV 431 V ++A VL GV A+ + + +T AEVD +V Sbjct: 351 VQRLADNGILAIANTGSR---------VLDVLGVND--VGGAVTVGLAHYSTMAEVDQLV 399 Query: 432 QDL 434 + L Sbjct: 400 RAL 402 >5HH9-A nrPDB Length = 390 Score = 200 bits (509), Expect = 8e-52, Method: Composition-based stats. Identities = 86/410 (20%), Positives = 144/410 (35%), Gaps = 64/410 (15%) Query: 40 TPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIIN-AARESLAKMIGGKPQDIIFTSG 98 T V +A+ + NP R+ AR + +P + T Sbjct: 25 TSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGS 84 Query: 99 GTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEE 158 T+ G + + +TSS EH S LE+ + Sbjct: 85 TTD--------------------GLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKR 124 Query: 159 QVAAVTFVPVSKVSGQAEVDDIL----AAVRPTTRLVTIMLANNETGIVMPVPEISQRIK 214 V P+ K + D+IL A +RP TR++ + + +G+ +P+ EI + ++ Sbjct: 125 MGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVR 184 Query: 215 ALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKF-YGPR-IGALYIRG 272 LNQ+R I+ D G + V D D+ HK+ +GPR G + R Sbjct: 185 ELNQKRDEQD--RIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARS 242 Query: 273 LGEFTPLYPMLFGGGQERNFRPGTENTP-------MIAGLGKAAELVTQNCE-AYEAHMR 324 L P + + NF GT TP LG A EL Q + +A + Sbjct: 243 EQLQEHLVPSIPTFSRADNF--GTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIH 300 Query: 325 DVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASV 384 + YL++RL ++ L + + R++G Sbjct: 301 QLNAYLKQRLGEHP---KVRLVTPTSPE------LSSGFTFFRVEGRD------------ 339 Query: 385 GAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDL 434 C + + ++S V DV +RL+ AE+D V++ L Sbjct: 340 ---CEAVAKHLMAHRVISDAVDRDV-GPVVRLAPSLLNDEAEIDRVLEIL 385 >1QZ9-A nrPDB Length = 416 Score = 82.6 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 79/463 (17%), Positives = 143/463 (30%), Gaps = 103/463 (22%) Query: 8 GRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGN--PSSPY 65 +D+ AP Q PE +Y+D N+ + + E WGN S Sbjct: 12 AQDSLAPLRQQ------FALPEGVIYLDGNSLGARPVAALARAQAVIAEEWGNGLIRSWN 65 Query: 66 SAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNL--VIHSVVKHFHANQTSKGH 123 SAG + D+ LA +IG + +++ T T S NL V+ + ++ Sbjct: 66 SAGWR--DLSERLGNRLATLIGARDGEVVVTD--TTSINLFKVLSAALRVQATRS----- 116 Query: 124 TGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVE------EQVAAVTFVPVSKVSGQAEV 177 + I + S ++ E +Q + V Sbjct: 117 ----------PERRVIVTET---SNFPTDLYIAEGLADMLQQGYTLRLVD--------SP 155 Query: 178 DDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQA 237 +++ A+ T +V + N +TG + + ++ L D A + Sbjct: 156 EELPQAIDQDTAVVMLTHVNYKTGYMHDMQALTALSHECGA----------LAIWDLAHS 205 Query: 238 LGKQRVDVEDLGVDFLTIVGHKF--YGPRIGALYIRGLGEFTPLYPMLFGG--GQERNFR 293 G VD+ G D+ +K+ GP A ++ + L P G G R F Sbjct: 206 AGAVPVDLHQAGADYAIGCTYKYLNGGPGSQA-FVWVSPQLCDLVPQPLSGWFGHSRQFA 264 Query: 294 P---------------GTENTPMIAGLGKAAE-LVTQNCEAYEAHMRDVRDYLEERLEAE 337 GT+ +A + + + + + D E +E Sbjct: 265 MEPRYEPSNGIARYLCGTQPITSLAMVECGLDVFAQTDMASLRRKSLALTDLFIELVEQR 324 Query: 338 FGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPS 397 + L + +R + S +G+ V+ GD Sbjct: 325 CAAHELTLVTPREHAKRGS---HVSFE--HPEGYAVIQALID---------RGVIGDYRE 370 Query: 398 PVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQ 440 P ++ +G TT EV VQ L + + + Sbjct: 371 PRIMRFGFTP------------LYTTFTEVWDAVQILGEILDR 401 >5DX5-A nrPDB Length = 400 Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 72/385 (18%), Positives = 130/385 (33%), Gaps = 31/385 (8%) Query: 69 RKAKDIINAARESLAKMIGGKPQDIIFTSG---GTESNN-LVIHSVVKHFHANQTSKGHT 124 + + I ++A + + G + I G TE N L + + + G Sbjct: 33 QTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMGAI 92 Query: 125 GGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAV 184 + H + S + L H + VTFV VS +D++ A+ Sbjct: 93 AASLWSALKSGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDVS------NLDEVKNAL 146 Query: 185 RPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVD 244 +P T++V + N T V + +IS + N+E V D + Sbjct: 147 KPNTKVVYLETPANPTLKVTDIRKISNMVHESNKE--------CFVFVDNTFCTPYIQRP 198 Query: 245 VEDLGVDFLTIVGHKF---YGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPM 301 +E LG D + K+ +G I + G EF LFG G + + Sbjct: 199 LE-LGADVVVHSATKYLNGHGDVIAG-FAVGKEEFIN-QVKLFGIKDMTGSVTGPFESFL 255 Query: 302 IA-GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPN-TC 359 I G+ + ++C+ + + + G + +LP Sbjct: 256 IIRGMKTLQLRMEKHCKNAMEVAKFLESHPAVEKVYYPGLESFKYYQLAREQMKLPGAMI 315 Query: 360 NFSIRGPRLQGHVVLAQCR--VLMASVGAA---CHSDHGDQPSPVLLSYGVPFDVARNAL 414 +F ++G +G +V+ + L S+G + SP ++ + Sbjct: 316 SFELKGGVEEGKIVMNNVKLATLAVSLGDSETLIQHPASMTHSPYTAEERKAAGISDGLV 375 Query: 415 RLSVGRSTTRAEVDLVVQDLKQAVA 439 RLSVG +D + Q L V Sbjct: 376 RLSVGLEDAEDIIDDLKQALDLIVK 400 >5V1X-E nrPDB Length = 501 Score = 64.1 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 41/257 (15%), Positives = 81/257 (31%), Gaps = 30/257 (11%) Query: 44 PEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESN 103 P IQ ++ + + +++ +R ++A ++ + ++F + T Sbjct: 59 PSAIQQKLRSY-QTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGV 117 Query: 104 NLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAV 163 N V+ ++V + K I +E + Sbjct: 118 NTVLRNIVWSADGKDEILYFDTIFGACGKT-----IDYVIEDKRGIVSSR-------CIP 165 Query: 164 TFVPVSKVSGQAEVDDILAAVRP---TTRLVTIMLANNETGIVMPVPEISQRIKALNQER 220 P A D + R RL I + ++ G+ P +I + K Sbjct: 166 LIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKE----- 220 Query: 221 VAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKF-YGPRIGALY---IRGLGEF 276 I+ D AQ +G + + + DFL HK+ + PR A++ +R Sbjct: 221 -----EEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLI 275 Query: 277 TPLYPMLFGGGQERNFR 293 P G + R Sbjct: 276 RSTLPTSHGFVPQVGNR 292 >2DR1-A nrPDB Length = 386 Score = 59.1 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 48/308 (15%), Positives = 96/308 (31%), Gaps = 50/308 (16%) Query: 152 LEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVR--PTTRLVTIMLANNETGIVMPVPEI 209 + +VE + + +D+ A+R P VTI TG++ P+PE+ Sbjct: 110 YKEVVESNGRKAVVLEYEPGK-AVKPEDLDDALRKNPDVEAVTITYNETSTGVLNPLPEL 168 Query: 210 SQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALY 269 ++ K ++ LV DA A+G + + G+D + K +G G Sbjct: 169 AKVAKEHDK----------LVFVDAVSAMGGADIKFDKWGLDVVFSSSQKAFGVPPGLAI 218 Query: 270 IRGLGEFTPLYPMLFGGG------------QERNFRPGTENTPMIAGLGKAAELVTQNCE 317 F + + G +E+ P T P + G+ A + E Sbjct: 219 GAFSERFLEIAEKMPERGWYFDIPLYVKYLKEKESTPSTPPMPQVFGINVALRI----IE 274 Query: 318 AYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNF-SIRGPRLQGHVVLAQ 376 + + Y + G + I L+ P + G + + Sbjct: 275 KMGGKEKWLEMYEKRAKMVREGVREIGLDILAEPGHESPTITAVLTPPGIKGDEVYEAMR 334 Query: 377 CRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQ 436 R + G V R+ ++ ++ +L++ Sbjct: 335 KRGFELAKGYG--------------------SVKEKTFRIGHMGYMKFEDIQEMLDNLRE 374 Query: 437 AVAQLEDQ 444 + +L+ Q Sbjct: 375 VINELKKQ 382 >1XI9-A nrPDB Length = 406 Score = 57.6 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 54/328 (16%), Positives = 108/328 (32%), Gaps = 49/328 (14%) Query: 31 KVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKP 90 V D+ ++ +A+ + +G+ K I+ RE + P Sbjct: 48 PVKFDFQPPEHMKEAYCKAIKEG-HNYYGDSEGLPEL---RKAIVE--REKRKNGVDITP 101 Query: 91 QDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRL 150 D+ T+ TE+ L+ + + Sbjct: 102 DDVRVTAAVTEALQLI---------------------FGALLDPGDEILVPG----PSYP 136 Query: 151 PLEHLVEEQVAA-VTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEI 209 P LV+ V + + + Q ++DDI + T+ + ++ NN TG + + Sbjct: 137 PYTGLVKFYGGKPVEYRTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYDKKTL 196 Query: 210 SQRIKALNQERVAAGLPPI--LVHTDAAQ-ALGKQRVDVEDLGVDFLTIVGHKFY---GP 263 + + + + I L+ + + G DV + ++ L+ K Y G Sbjct: 197 EEILNIAGEYEIPVISDEIYDLMTYEGEHISPGSLTKDVPVIVMNGLS----KVYFATGW 252 Query: 264 RIGALYIRG-LGEFTPLYPMLFGGGQERNFRPGTE-NTPMIAGLGKAAELVTQNCEAYEA 321 R+G +Y + + + + + R P T IAGL + + Y Sbjct: 253 RLGYMYFVDPENKLSEVREAIDRLARIR-LCPNTPAQFAAIAGLTGPMDY----LKEYMK 307 Query: 322 HMRDVRDYLEERLEAEFGQKRIHLNSQF 349 +++ RDY+ +RL G F Sbjct: 308 KLKERRDYIYKRLNEIPGISTTKPQGAF 335 >3OP7-A nrPDB Length = 375 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 52/294 (17%), Positives = 113/294 (38%), Gaps = 60/294 (20%) Query: 79 RESLAKM-IGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPH 137 ++S++++ G KP+ I+ T+G T +N LV++S+++ H Sbjct: 69 KKSVSQLYTGVKPEQILQTNGATGANLLVLYSLIE---------------------PGDH 107 Query: 138 FITSSVEHDSIRLPLEHLV---EEQVAAVTFVPVSKVSG-QAEVDDILAAVRPTTRLVTI 193 I S+ + L + A V + + +G +++ + +RPTT+++ I Sbjct: 108 VI-------SLYPTYQQLYDIPKSLGAEVDLWQIEEENGWLPDLEKLRQLIRPTTKMICI 160 Query: 194 MLANNETGIVMP---VPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGV 250 ANN TG VM + E+ + + ++ + D + ++V D G+ Sbjct: 161 NNANNPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSFSELD----VPSI-IEVYDKGI 215 Query: 251 DFLTIVGHKFYG-PRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMI------- 302 ++ K Y P I ++ + T + R++R T + Sbjct: 216 AVNSLS--KTYSLPGIRIGWVAANHQVTDIL---------RDYRDYTMICAGVFDDLVAQ 264 Query: 303 AGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLP 356 L E++ +N E ++ + ++EE + + + S +P Sbjct: 265 LALAHYQEILERNRHILEENLAILDQWIEEEPLVSYIRPAVVSTSFVKIAVDMP 318 >4Q6R-A nrPDB Length = 511 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 52/296 (17%), Positives = 96/296 (32%), Gaps = 32/296 (10%) Query: 43 EPEVIQAMTKAMWEA-WGNPSSPYSAGRKAKDIINAARESLA-KMIGGKPQDI-IFTSGG 99 E ++ + + KA + W NP + I A +A + G P TSGG Sbjct: 96 EEKLTELLVKAYGDFAWSNP--LHPDIFPGLRKIEAEIVRIACSLFNGGPDSCGCVTSGG 153 Query: 100 TESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQ 159 TES + + P + H + Sbjct: 154 TESILMACKAYRDLAFEKGIKT--------------PEIVAPQSAHAA----FNKAASYF 195 Query: 160 VAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR-IKALNQ 218 + VP++K+ + +V + A+ T ++ G++ PVPE+++ +K Sbjct: 196 GMKIVRVPLTKMM-EVDVRAMRRAISRNTAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIP 254 Query: 219 ERVAAGLPPILVHTDAAQALG-KQRVDVEDLGVDFLTIVGHKF-YGPRIGALYIRGLGEF 276 V A L L+ + D GV ++ HK+ Y P+ +L + ++ Sbjct: 255 LHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKY 314 Query: 277 TPLY----PMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRD 328 GG G+ I+ AA + EA + ++ Sbjct: 315 RNYQFFVDTDWQGGIYASPTIAGSRP-GGISAACWAALMHFGENGYVEATKQIIKT 369 >3ZRR-A nrPDB Length = 384 Score = 56.0 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 47/323 (14%), Positives = 92/323 (28%), Gaps = 55/323 (17%) Query: 85 MIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVE 144 ++ G ++ FTS E + +S+ + SK + + +TS ++ Sbjct: 18 LVAGLENNVGFTS--KEFVEALAYSLKGLRYVMGASKNYQPLIIPGGGTSAMESVTSLLK 75 Query: 145 HDSIR---------LPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIML 195 + E + + V + S + + +LV + Sbjct: 76 PNDKILVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVEEEVRKSEYKLVALTH 135 Query: 196 ANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTI 255 TG+ PV ++ +I+ L+ D ++G + V E+ VD Sbjct: 136 VETSTGVREPVKDVINKIR----------KYVELIVVDGVSSVGAEEVKAEEWNVDVYLT 185 Query: 256 VGHK-----------FYGPRIGALYIRGLG--------EFTPLYPMLFGGGQERNFRPGT 296 K P+ AL I + P++ G + + T Sbjct: 186 ASQKALGSAAGLGLLLLSPK--ALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAYFAT 243 Query: 297 ENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYL----EERLEAEFGQKRIHLNSQF--- 349 +I L +A L+ + + E L E +R S Sbjct: 244 PPVHVILQLAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNTVTG 303 Query: 350 ------PGTQRLPNTCNFSIRGP 366 + L T N + Sbjct: 304 VILKVADPQKVLAGTVNEGVEFA 326 >1V2E-A nrPDB Length = 381 Score = 56.0 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 56/310 (18%), Positives = 107/310 (34%), Gaps = 59/310 (19%) Query: 39 TTPLEPEVIQAMTKAM--WEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFT 96 + P P +++A+ +A+ + + P+ + RE+LA+ +P+ ++ T Sbjct: 36 SNPPPPFLLEAVRRALGRQDQYAPPAGLPAL-----------REALAEEFAVEPESVVVT 84 Query: 97 SGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLV 156 SG TE+ +++ S+V G + + LP L Sbjct: 85 SGATEALYVLLQSLV---------------------GPGDEVVVLE-PFFDVYLPDAFLA 122 Query: 157 EEQVAAVTFVPVSKVSG--QAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIK 214 A V + + ++ + A+ P TR + + N TG+V E+ + Sbjct: 123 ---GAKARLVRLDLTPEGFRLDLSALEKALTPRTRALLLNTPMNPTGLVFGERELEAIAR 179 Query: 215 ALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVD--FLTIVGHK---FYGPRIGALY 269 + + G++ + + + F K G R+G + Sbjct: 180 LARAHDLFLISDEVYDEL----YYGERPRRLREFAPERTFTVGSAGKRLEATGYRVGWIV 235 Query: 270 IRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNC--EAYEAHMRDVR 327 P L G R + + TP+ AG+ +A +L + EA R R Sbjct: 236 GPK-----EFMPRLAG---MRQWTSFSAPTPLQAGVAEALKLARREGFYEALREGYRRRR 287 Query: 328 DYLEERLEAE 337 D L L A Sbjct: 288 DLLAGGLRAM 297 >5K1R-A nrPDB Length = 480 Score = 55.7 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 62/197 (31%), Gaps = 31/197 (15%) Query: 107 IHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFV 166 S+ + + + +P I + H + VT Sbjct: 121 ALSLGGTESILNATLAYREKARAERGIERPRMIWPASAHPA----FRKAAHLFGFDVTVA 176 Query: 167 PVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLP 226 P+ V+ Q + D + AV T ++ N G + P+ +S + Sbjct: 177 PIDPVTMQVDADFVRDAVDANTVMLVGSACNYPYGTIDPIGALSAIAVEKD--------- 227 Query: 227 PILVHTDAA---------QALGKQRV---DVEDLGVDFLTIVGHKF-YGPRIGALYIRGL 273 + +H D +ALG + D GV ++ HKF YGP+ G++ Sbjct: 228 -VWLHVDGCLGGWMLPWGEALGYPDIPAFDFRLPGVTSISADTHKFGYGPKGGSVLAWRD 286 Query: 274 GEFTP----LYPMLFGG 286 F L GG Sbjct: 287 ASFRRHQYFLMTDWVGG 303 >2BKW-A nrPDB Length = 385 Score = 55.7 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 39/232 (16%), Positives = 70/232 (30%), Gaps = 33/232 (14%) Query: 157 EEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTR-LVTIMLANNETGIVMPVPEISQRIKA 215 A V V K+ ++ I + + VT+ + T ++ + ISQ IK Sbjct: 106 RSYGAQVDVVRPLKIGESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSDLKAISQAIK- 164 Query: 216 LNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGE 275 P DA ++G + + ++ GVDF K G G Sbjct: 165 -------QTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSR 217 Query: 276 FTPLYPMLFGGGQ--------------ERNFRPG------TENTPMIAGLGKAA-ELVTQ 314 F G N+ G T +I L A E++ + Sbjct: 218 FMDYALNDSKNGHVHGYFSSLRRWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEE 277 Query: 315 NCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGP 366 R++ D+ ++ L ++ S++P + P Sbjct: 278 GLHKRWDLHREMSDWFKDSL---VNGLQLTSVSRYPSNMSAHGLTAVYVADP 326 >4W8I-A nrPDB Length = 551 Score = 54.9 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 57/374 (15%), Positives = 106/374 (28%), Gaps = 53/374 (14%) Query: 35 DYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDI- 93 D A + P+ + + K ++ A + + + + + G + Sbjct: 101 DSGALYAIHPKELTELLKEVYGATALTNPLHDKWPRINAMQAEVIRWCQNLFHGSKEGYG 160 Query: 94 IFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLE 153 + T GGT S + + +KG P + H + + Sbjct: 161 LLTHGGTTSI----IEAMAAYVIRARAKGIDY----------PEIVVPETAHAA----FK 202 Query: 154 HLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRI 213 E A + VPV K +G + + + + T ++ + GI P+ E+ Q Sbjct: 203 KAAELTGAILITVPVDKKTGAVNPNVMSSYITRNTAVMVGSAPSFMNGIHDPISELGQLA 262 Query: 214 KALNQERVAAGLPPILVHTDAAQA--------LGKQRVDVEDLGVDFLTIVGHKFY---- 261 K N + H DA + +D GV ++ HK+ Sbjct: 263 KKKN----------VPFHVDACLGGFLTAFLDTSSEPMDFRVPGVTSISADLHKYGCCPK 312 Query: 262 ----------GPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAEL 311 P + P + G T G K E+ Sbjct: 313 GTSVCLFSEDSPALSVYAALNWSGGLYATPGILDGSTSGARVAEVYATLSYYGKNKYQEI 372 Query: 312 VTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGH 371 A +++ +EE ++ N Q+ NTCN L+ Sbjct: 373 AKSIIRLRNAIQKELTALVEEGNGLTSEDIYVYGNPQWSILGFRSNTCNAHFIADELEKR 432 Query: 372 VVLAQCRVLMASVG 385 + +L G Sbjct: 433 G--WKLNLLQNPDG 444 >1M32-A nrPDB Length = 366 Score = 53.0 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 32/202 (15%), Positives = 61/202 (30%), Gaps = 28/202 (13%) Query: 174 QAEVDDILAAV--RPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVH 231 + +V I A + PT + ++ + TG++ P+ E+ + Sbjct: 116 RPDVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVGALAHRYGKT----------YI 165 Query: 232 TDAAQALGKQRVDVEDLGVDFLTIVGHK-FYG-PRIGALYIRG----------LGEFTPL 279 DA + G +D+ L +D+L +K G P + R L Sbjct: 166 VDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPGFAFVIAREQKLAACKGHSRSLSLDL 225 Query: 280 YPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFG 339 Y T T + +A + + + H R Y + + G Sbjct: 226 YAQWRCMEDNHGKWRFTSPTHTVLAFAQALKELAKEGGVAARHQR----YQQNQRSLVAG 281 Query: 340 QKRIHLNSQFPGTQRLPNTCNF 361 + + N+ P F Sbjct: 282 MRALGFNTLLDDELHSPIITAF 303 >2E7J-A nrPDB Length = 371 Score = 53.0 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 63/382 (16%), Positives = 112/382 (29%), Gaps = 70/382 (18%) Query: 70 KAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHS 129 K I + L K +G + T+G E+ V+HS+ K Sbjct: 51 KTPPIHDFIHNQLPKFLGCDVARV--TNGAREAKFAVMHSLAK----------------- 91 Query: 130 PVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVP-VSKVSGQAEVDDILAAVRPTT 188 + H S + E + VP ++ + T Sbjct: 92 ----KDAWVVMDENCHYSSYV----AAERAGLNIALVPKTDYPDYAITPENFAQTIEETK 143 Query: 189 R-----LVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRV 243 + L I + G + V +I++ + + + + A A+G+ V Sbjct: 144 KRGEVVLALITYPDGNYGNLPDVKKIAKVCSEYD----------VPLLVNGAYAIGRMPV 193 Query: 244 DVEDLGVDFLTIVGHK---FYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTP 300 ++++G DF+ GHK GP IG + ++ L +E T Sbjct: 194 SLKEIGADFIVGSGHKSMAASGP-IGVMGMKEEWAEIVLRRSEKYKNKEVELLGCTARGA 252 Query: 301 MIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCN 360 I L + V + + ++ + R R AE + I P L Sbjct: 253 TIITLMASFPHVRERIKRWDEEVEKAR-----RFAAEMEKLGIKQLGDNPHNHDL----- 302 Query: 361 FSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGR 420 L A+ HG +P G+ + LS Sbjct: 303 MFFHAEVLYEISKKAKGGRFFLYRELKSRKIHGIKP-------GLTRYFKLSTYGLS--- 352 Query: 421 STTRAEVDLVVQDLKQAVAQLE 442 EVD V+ K+ + + Sbjct: 353 ---DEEVDYVLNAFKEIIEKYS 371 >5O5C-A nrPDB Length = 519 Score = 53.0 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 49/221 (22%), Positives = 81/221 (36%), Gaps = 30/221 (13%) Query: 94 IFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGH-HSPVKGAKPHFITSSVEHDSIRLPL 152 IFTSGGT+S NL+ + + GH H P AK TS + H SI+ + Sbjct: 165 IFTSGGTQS-NLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSHFSIQKSM 223 Query: 153 EHLVEEQVAAVTFVPVS-KVSGQAEVD----DILAAVRPTTRLVTIMLANNET--GIVMP 205 L A +PV + +VD ++ ++ V ++ + T G + P Sbjct: 224 AILGLGYDA---VIPVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDP 280 Query: 206 VPEISQRIKALNQERVAAGLPPILVHTDAAQALG------KQRVDVEDLGVDFLTIVGHK 259 + IS+ K + +H DAA G + D +T+ HK Sbjct: 281 LGAISELCK----------HHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHK 330 Query: 260 FYGPRI--GALYIRGLGEFTPLYPMLFGGGQERNFRPGTEN 298 + + GA ++R + + + GT N Sbjct: 331 SFFQTVSCGAFFVRDKHHLSHVTHHADYLNPLSAQQEGTPN 371 >3HBX-A nrPDB Length = 502 Score = 49.1 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 54/328 (16%), Positives = 107/328 (32%), Gaps = 47/328 (14%) Query: 71 AKDIINAARESLAKMIGGKPQDI-----IFTSGGTESNNLVIHSVVKHFHANQTSKGHTG 125 ++ N +A + ++ + T G +E+ L + + + + ++G Sbjct: 93 TTELQNRCVNMIAHLFNAPLEEAETAVGVGTVGSSEAIMLAGLAFKRKWQNKRKAEGKPV 152 Query: 126 GHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVR 185 KP+ +T + ++++ E + V +S+ + + V Sbjct: 153 D--------KPNIVTGA----NVQVCWEKFARYFEVELKEVKLSEGYYVMDPQQAVDMVD 200 Query: 186 PTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDV 245 T V +L + G V ++ + N+E +H DAA Sbjct: 201 ENTICVAAILGSTLNGEFEDVKLLNDLLVEKNKET----GWDTPIHVDAASGGFIAPFLY 256 Query: 246 EDLGVDF-------LTIVGHKFYG---PRIGALYIRGLGEFTP---LYPMLFGGGQ---E 289 +L DF + + GHK YG IG + R + + G Q Sbjct: 257 PELEWDFRLPLVKSINVSGHK-YGLVYAGIGWVIWRNKEDLPEELIFHINYLGADQPTFT 315 Query: 290 RNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQF 349 NF G+ IA + L + + R+ L E LE +R ++ S+ Sbjct: 316 LNFSKGSSQV--IAQYYQLIRLGHEGYRNVMENCRENMIVLREGLEK---TERFNIVSKD 370 Query: 350 PGTQRLPNTCNFSIRGPRLQGHVVLAQC 377 G FS++ ++ Sbjct: 371 EGVP----LVAFSLKDSSCHTEFEISDM 394 >3DR4-A nrPDB Length = 391 Score = 48.7 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 52/344 (15%), Positives = 100/344 (29%), Gaps = 37/344 (10%) Query: 109 SVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPV 168 V N + + G I S+ + + + + A V Sbjct: 70 GVKHAIACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYC----GATPVLVDN 125 Query: 169 SKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPI 228 + + + A + P T+ + + + + P+ E+++R + Sbjct: 126 DPRTFNLDAAKLEALITPRTKAIMPVHLYGQICDMDPILEVARR-------------HNL 172 Query: 229 LVHTDAAQALGKQ---RVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFG 285 LV DAA+A+G + + G+ G + + +L G Sbjct: 173 LVIEDAAEAVGATYRGKKSGSLGDCATFSFFGNAIITTGEGGMITTNDDDLAAKMRLLRG 232 Query: 286 GGQERNFRPGTE---------NTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEA 336 G + N R N GL + + + + A V + E++L A Sbjct: 233 QGMDPNRRYWFPIVGFNYRMTNIQAAIGLAQ-----LERVDEHLAARERVVGWYEQKL-A 286 Query: 337 EFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQP 396 G + + G G V+ L H H P Sbjct: 287 RLGNRVTKPHVALTGRHVFWMYTVRLGEGLSTTRDQVIKDLDALGIESRPVFHPMHIMPP 346 Query: 397 SPVLLSYGVPFDVARNALRLSVGRST--TRAEVDLVVQDLKQAV 438 L + + A L++ T A++D V+ L Q + Sbjct: 347 YAHLATDDLKIAEACGVDGLNLPTHAGLTEADIDRVIAALDQVL 390 >1IBJ-A nrPDB Length = 464 Score = 48.7 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 76/434 (17%), Positives = 133/434 (30%), Gaps = 89/434 (20%) Query: 25 HNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAK 84 ++ +Y T +P I+ + PY R +A LAK Sbjct: 101 FDAMSTPLY---QTATFKQPSAIE-------------NGPYDYTRSGNPTRDALESLLAK 144 Query: 85 MIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVE 144 + + FTSG + S V H N G V G ++ Sbjct: 145 LDKAD-RAFCFTSG------MAALSAVTHLIKN----GEEIVAGDDVYGGSDRLLS---- 189 Query: 145 HDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVM 204 +V V V ++D++ AA+ P T+LV + T Sbjct: 190 ---------QVVPRSGVVVKRV------NTTKLDEVAAAIGPQTKLV---WLESPTNPRQ 231 Query: 205 PVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPR 264 + +I + + + + LV D + +E LG D + KF Sbjct: 232 QISDIRKISEMAHAQGA-------LVLVDNSIMSPVLSRPLE-LGADIVMHSATKFIAGH 283 Query: 265 ----IGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYE 320 G L ++G +Y + G G L + + + E + Sbjct: 284 SDVMAGVLAVKGEKLAKEVYFLQNSEG------SGLAPFDCWLCL-RGIKTMALRIEKQQ 336 Query: 321 AHMRDVRDYLEE--RLEAEFGQKRIHLNS---QFPGTQRLPNTCNFSIRGPRLQGHVVLA 375 + R + YL R++ + F + + +F L H+V Sbjct: 337 ENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVET 396 Query: 376 QCR-VLMASVGAA-------CHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEV 427 + S G+ C H P+ V + G+ D+ +R+S G +V Sbjct: 397 TKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDL----VRISAGI----EDV 448 Query: 428 DLVVQDLKQAVAQL 441 D ++ DL A Sbjct: 449 DDLISDLDIAFKTF 462 >3F9T-A nrPDB Length = 397 Score = 48.7 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 80/278 (28%), Gaps = 49/278 (17%) Query: 76 NAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAK 135 A L ++ K SGGTE+N + + + + + H Sbjct: 72 EKAVALLGSLLNNKDAYGHIVSGGTEANLMALRCIKNIWREKRRKGLSKNEH-------- 123 Query: 136 PHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRP-TTRLVTIM 194 P I H S E E + P+ K + + AV + + Sbjct: 124 PKIIVPITAHFS----FEKGREMMDLEYIYAPI-KEDYTIDEKFVKDAVEDYDVDGIIGI 178 Query: 195 LANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQR------------ 242 E G + + E+S+ K N I +H DAA Sbjct: 179 AGTTELGTIDNIEELSKIAKENN----------IYIHVDAAFGGLVIPFLDDKYKKKGVN 228 Query: 243 --VDVEDLGVDFLTIVGHKFYGPRI--GALYIRGLG--EFTPLYPMLFGGGQERNFRPGT 296 D LGVD +TI HK I G + + +G + + ++ Sbjct: 229 YKFDFS-LGVDSITIDPHKMGHCPIPSGGILFKDIGYKRYLDVDAPYLTETRQATI---- 283 Query: 297 ENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERL 334 G G A E + V + +E L Sbjct: 284 --LGTRVGFGGACTYAVLRYLGREGQRKIVNECMENTL 319 >1O4S-A nrPDB Length = 389 Score = 46.8 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 61/419 (14%), Positives = 130/419 (31%), Gaps = 104/419 (24%) Query: 41 PLEPEVIQAMTKAMWE---AWGNPSSPYSAGRKAKDIINAARESLAKMIGGK------PQ 91 P V++ + + + + +P Y RE +AK IG + P Sbjct: 54 PTPEPVVEEAVRFLQKGEVKYTDPRGIYEL-----------REGIAKRIGERYKKDISPD 102 Query: 92 DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFIT-SSVEHDSIRL 150 ++ T+G ++ + I S V + Sbjct: 103 QVVVTNGAKQAL---------------------FNAFMALLDPGDEVIVFSPV--WVSYI 139 Query: 151 PLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMP---VP 207 P ++ + Q ++++ + T+ V I NN TG+V + Sbjct: 140 P--QIILAGGTVNVVETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRREFLE 197 Query: 208 EISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTI-----VGHKFYG 262 + + K N ++ + LV+TD ++ +DV + G D + H G Sbjct: 198 GLVRLAKKRNFYIISDEVYDSLVYTDEFTSI----LDVSE-GFDRIVYINGFSKSHSMTG 252 Query: 263 PRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAH 322 R+G Y+ + + T + A + + + Sbjct: 253 WRVG--YLISSEKVATAVS---------KIQSHTTSCINTVAQYAALKALEVDNSYMVQT 301 Query: 323 MRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMA 382 ++ ++++ ERL+ + G K + F F +RG ++ L + + + Sbjct: 302 FKERKNFVVERLK-KMGVKFVEPEGAF--------YLFFKVRGDDVKFCERLLEEKKVAL 352 Query: 383 SVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQL 441 G+A + +RLS S ++ + + L + L Sbjct: 353 VPGSAF--------------------LKPGFVRLSFATS-----IERLTEALDRIEDFL 386 >5GP4-C nrPDB Length = 468 Score = 46.4 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 59/326 (18%), Positives = 107/326 (32%), Gaps = 32/326 (9%) Query: 40 TPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGG 99 T +EPE ++ M + E S Y + +I N +A + P+ FT G Sbjct: 68 TYMEPEAVELMKDTL-EKNAIDKSEYP---RTAEIENRCVNIIANLWHA-PEAESFT--G 120 Query: 100 TESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQ 159 T + ++ + + + +P+ + S+ ++ E Sbjct: 121 TSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISA----GYQVCWEKFCVYW 176 Query: 160 VAAVTFVPVSKVSGQAEVDDILAAVRPTTR-LVTIMLANNETGIVMPVPEISQRIKALNQ 218 + VP+ VD +L V T +V IM TG + + ++ N+ Sbjct: 177 DIDMHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGIT-YTGQYDDLARLDAVVERYNR 235 Query: 219 ERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDF-------LTIVGHKFYG---PRIGAL 268 P+ +H DAA +L DF + GHK YG P +G + Sbjct: 236 TT----KFPVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHK-YGLVYPGVGWV 290 Query: 269 YIRGLGEFTP--LYPMLFGGGQERNFRPG-TENTPMIAG-LGKAAELVTQNCEAYEAHMR 324 R ++ + + GG+ + + + G + Sbjct: 291 IWRDQQYLPKELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTH 350 Query: 325 DVRDYLEERLEAEFGQKRIHLNSQFP 350 DV YL + L G I+ + P Sbjct: 351 DVARYLAKSLTKLGGFSLINDGHELP 376 >3KGX-A nrPDB Length = 393 Score = 46.0 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 46/305 (15%), Positives = 91/305 (29%), Gaps = 54/305 (17%) Query: 155 LVEEQVAAVTFVPVSKVSGQAEVDDILAAV-RPTTRLVTIMLANNETGIVMPVPEISQRI 213 + + A V + + K + ++ + + L+ ++ + TG+V P+ + Sbjct: 116 IADRIGARVHQM-IKKPGEHYTLQEVEEGLAQHKPVLLFLVHGESSTGVVQPLDGFGELC 174 Query: 214 KALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGA------ 267 L+ D+ +LG + ++ G+D + K G Sbjct: 175 H----------RYQCLLLVDSVASLGGVPIYMDQQGIDIMYSSSQKVLNAPPGISLISFN 224 Query: 268 ------LYIRGLG------EFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQN 315 +Y R + T L + G+ R T T + A + Q Sbjct: 225 DKAKYKVYSRKTKPVSFYTDITYLAKLWGCEGETRVIHHTTPVTSLYCLRESLALIAEQG 284 Query: 316 CEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLA 375 E R+ +L + L+ E G K RLP ++ +V Sbjct: 285 LENCWRRHREATAHLHKHLQ-EMGLKFF----VKDPEIRLPTITTVTVPAGYNWRDIVSY 339 Query: 376 QCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRST-TRAEVDLVVQDL 434 + G + LR+ + T VD V + L Sbjct: 340 VLDHFSIEISGG---------------LGPTEERV---LRIGLLGYNATTENVDRVAEAL 381 Query: 435 KQAVA 439 ++A+ Sbjct: 382 REALQ 386 >2YRI-A nrPDB Length = 353 Score = 44.9 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 45/248 (18%), Positives = 72/248 (29%), Gaps = 32/248 (12%) Query: 181 LAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGK 240 A R R+V ++ TG++ P I K L DA LG Sbjct: 118 RALKRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGA----------LFFLDAVTTLGM 167 Query: 241 QRVDVEDLGVDFLTIVGHKFY-------GPRIGALYIRGLGEFTPLYPMLFGGGQERNFR 293 + +GVD G + P +L R + + E R Sbjct: 168 LPFSMRAMGVD-YAFTGSQKCLSAPPGLAPIAASLEARKAFTGKRGWYLDLARVAEHWER 226 Query: 294 PG---TENTPMIAGLGKAAELVTQN-CEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQF 349 G T + L +A +LV + A E R+V ++ E L+A + Sbjct: 227 GGYHHTTPVLLHYALLEALDLVLEEGVAARERRAREVYAWVLEELKAR-------GFRPY 279 Query: 350 PGTQRLPNTCNF-SIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFD 408 P LP G V + + G + L+ G + Sbjct: 280 PKASPLPTVLVVRPPEGVDADRLVRALYAEGVAVAGGIGPTRGQVLRLG--LMGEGARRE 337 Query: 409 VARNALRL 416 + L+ Sbjct: 338 AYQAFLKA 345 >3WKR-A nrPDB Length = 416 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 30/230 (13%), Positives = 67/230 (29%), Gaps = 56/230 (24%) Query: 44 PEVIQAMTKAMWEAWGNPSSPYSAGRKAK-DIINAARESLAKMIG---GKPQDIIFTSGG 99 P+ + W+ + + + I E +AK + +P T G Sbjct: 67 PKEAKKAVYEYWDGYSVCDYCHGRLDEVTCPPIKDFLEDIAKFLNMDCARP-----THGA 121 Query: 100 TESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQ 159 E +V+H++ K + + H + + E Sbjct: 122 REGKFIVMHAICKE---------------------GDYVVLDKNAHYTSYVAAER----- 155 Query: 160 VAAVTFVPVSKVSG----QAEVDDILAAVR------PTTRLVTIMLANNETGIVMPVPEI 209 A + V + ++ + L+ + + E G + ++ Sbjct: 156 -AKLNVAEVGYEEEYPTYKINLEGYKEVIDNLEDKGKNVGLILLTHVDGEYGNLNDAKKV 214 Query: 210 SQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHK 259 + K I + A +G+ V+ +++ DF+ GHK Sbjct: 215 GKIAKEK----------GIPFLLNCAYTVGRMPVNGKEVKADFIVASGHK 254 >3FFH-A nrPDB Length = 363 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 52/131 (39%), Gaps = 26/131 (19%) Query: 79 RESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHF 138 R+ +A + +++IFT+G E L+ ++ + +T + + Sbjct: 73 RKEVADFYQLEEEELIFTAGVDELIELLTRVLL-------DTTTNTVMATPTFVQYRQNA 125 Query: 139 ITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANN 198 + + A V +P+ + G+ +++ +L A+ T +V I NN Sbjct: 126 LI------------------EGAEVREIPLLQ-DGEHDLEGMLNAIDEKTTIVWICNPNN 166 Query: 199 ETGIVMPVPEI 209 TG + + +I Sbjct: 167 PTGNYIELADI 177 >1J32-A nrPDB Length = 388 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 42/251 (16%), Positives = 75/251 (29%), Gaps = 18/251 (7%) Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR 212 E + + V + + + I A+ P T+L+ +N TG+V E+ Sbjct: 129 EMVKLAEGTPVILPTTVETQFKVSPEQIRQAITPKTKLLVFNTPSNPTGMVYTPDEVRAI 188 Query: 213 IKALNQERVAAGLPPIL--VHTDAAQALGKQRVDVEDLGVDFLT---IVGHKFYGPRIGA 267 + + + I + D AQ L E + + G R+G Sbjct: 189 AQVAVEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSVVCSGFAKTYAMTGWRVGF 248 Query: 268 LYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVR 327 L P++ + + T G A E + A + R Sbjct: 249 LAGP--------VPLVKAATKIQGHSTSNVCTFAQYGAIAAYENSQDCVQEMLAAFAERR 300 Query: 328 DYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAA 387 Y+ + L A G + + F + T S+ L + GAA Sbjct: 301 RYMLDALNAMPGLECPKPDGAFYMFPSIAKTGRSSLDFC-----SELLDQHQVATVPGAA 355 Query: 388 CHSDHGDQPSP 398 +D + S Sbjct: 356 FGADDCIRLSY 366 >5LUC-A nrPDB Length = 403 Score = 42.6 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 48/304 (15%), Positives = 90/304 (29%), Gaps = 56/304 (18%) Query: 157 EEQVAAVTFVPVSKVSG-QAEVDDILAAV-RPTTRLVTIMLANNETGIVMPVPEISQRIK 214 E A V P++K G + ++ + + L+ + + TG++ P+ + Sbjct: 128 ERIGARVH--PMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCH 185 Query: 215 ALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGA------- 267 L+ ++ +LG + ++ G+D L K G Sbjct: 186 ----------RYKCLLLVNSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSD 235 Query: 268 -----LYIRGLGEF-----TPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAE-LVTQNC 316 +Y R F +G + T + L ++ + Q Sbjct: 236 KAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGL 295 Query: 317 EAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQ 376 E R+ YL RL+A Q + RLP ++ +V Sbjct: 296 ENSWRQHREAAAYLHGRLQALGLQLFVK-----DPALRLPTVTTVAVPAGYDWRDIVSYV 350 Query: 377 CRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSV-GRSTTRAEVDLVVQDLK 435 + G LR+ + G + TR VD V + L+ Sbjct: 351 IDHFDIEI------------------MGGLGPSTGKVLRIGLLGCNATRENVDRVTEALR 392 Query: 436 QAVA 439 A+ Sbjct: 393 AALQ 396 >1U08-A nrPDB Length = 386 Score = 42.2 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 31/193 (16%), Positives = 61/193 (31%), Gaps = 25/193 (12%) Query: 44 PEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESN 103 P +Q N +P + + ++ I E L DI T+G TE+ Sbjct: 45 PRYLQERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATEAL 104 Query: 104 NLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAV 163 I ++V++ I +DS P L V Sbjct: 105 YAAITALVRN---------------------GDEVICFDPSYDS-YAPAIALS---GGIV 139 Query: 164 TFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAA 223 + + + + + A + TRLV + +N + V + + +A+ + Sbjct: 140 KRMALQPPHFRVDWQEFAALLSERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFV 199 Query: 224 GLPPILVHTDAAQ 236 + H + +Q Sbjct: 200 ISDEVYEHINFSQ 212 >2GB3-A nrPDB Length = 409 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 38/251 (15%), Positives = 79/251 (31%), Gaps = 56/251 (22%) Query: 53 AMWEAWGNPSSPYSAGRKAKDIINAARESLAKM------IGGKPQDIIFTSGGTESNNLV 106 + N A I RE+ A + KP++++ T+GG+E+ Sbjct: 61 FFERIYENKPEVVYYSHSA--GIWELREAFASYYKRRQRVDVKPENVLVTNGGSEAI--- 115 Query: 107 IHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPL--EHLVEEQVAAVT 164 + + + + P + ++A V Sbjct: 116 ------------------LFSFAVIANPGDEIL--------VLEPFYANYNAFAKIAGVK 149 Query: 165 FVPVSK--VSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVA 222 +PV++ G A ++ + + T+ + + N TG+V E+ ++ + Sbjct: 150 LIPVTRRMEEGFAIPQNLESFINERTKGIVLSNPCNPTGVVYGKDEMRYLVEIAERH--- 206 Query: 223 AGLPPILVHTDAAQALGKQR------VDVEDLGVDFLTIVGHKF--YGPRIGALYIRGLG 274 + + D + R + +E V + V KF G R+G L R Sbjct: 207 ----GLFLIVDEVYSEIVFRGEFASALSIESDKVVVIDSVSKKFSACGARVGCLITRNEE 262 Query: 275 EFTPLYPMLFG 285 + + G Sbjct: 263 LISHAMKLAQG 273 >1N8P-A nrPDB Length = 393 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 70/417 (16%), Positives = 130/417 (31%), Gaps = 80/417 (19%) Query: 51 TKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSG-GTESNNLVIHS 109 T + NP Y R ++A + + + F+SG T + ++ S Sbjct: 33 TTFKQSSPANPIGTYEYSRSQNPNRENLERAVAALENAQ-YGLAFSSGSATTA--TILQS 89 Query: 110 VVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVS 169 + + HA + G H K A H + +S +D Sbjct: 90 LPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTNDL---------------------- 127 Query: 170 KVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPIL 229 ++D+ ++ T+LV I N T V + +++ IK A ++ Sbjct: 128 -------LNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKK------HAAGQDVI 174 Query: 230 VHTDAAQALGKQ--RVDVEDLGVDFLTIVGHK-FYGPR---IGALYIRGLGEFTPLYPML 283 + D ++ G D + K G +G L + L + Sbjct: 175 LVVDNTFLSPYISNPLNF---GADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQ 231 Query: 284 FGGGQERNFRPGTENTPMIA-----GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEF 338 G +P A GL V Q + + E + + Sbjct: 232 NA--------IGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNY 283 Query: 339 GQKRIHLNSQFPGTQRL----PNTCNFSIRGPRLQGHVVLAQCR--VLMASVGAACHSDH 392 + H N Q +F I+G + R L S+G + Sbjct: 284 PGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGI---ES 340 Query: 393 GDQPSPVLLSYGVPFDVARNA------LRLSVGRSTTRAEVDLVVQDLKQAVAQLED 443 + V+ G+P + + +R+SVG + D +++D+KQA+ Q + Sbjct: 341 LLEVPAVMTHGGIPKEAREASGVFDDLVRISVGI----EDTDDLLEDIKQALKQATN 393 >3QI6-A nrPDB Length = 392 Score = 40.3 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 54/292 (18%), Positives = 97/292 (33%), Gaps = 37/292 (12%) Query: 159 QVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQ 218 V + PV A++D + AA+RPTTRL+ + N + + I+Q + Sbjct: 127 TGWNVEYTPV----ALADLDAVRAAIRPTTRLIWVETPTNPLLSIADIAGIAQLGADSSA 182 Query: 219 ERVAAGLPPILVHTDAAQALG--KQRVDVEDLGVDFLTIVGHKFYGPRI----GALYIRG 272 + V D A +Q + LG D + K+ G GAL Sbjct: 183 K----------VLVDNTFASPALQQPLS---LGADVVLHSTTKYIGGHSDVVGGALVTND 229 Query: 273 LGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRD---VRDY 329 + G G + L + ++N A + + + Sbjct: 230 EELDQSFAFLQNGAGAVPGPFDAYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTV 289 Query: 330 LEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACH 389 L L + G + + +R R + A+ + + + Sbjct: 290 LYPGLPSHPGHAVAARQMR-----GFGGMVSVRMRAGRTAAEQLCAKTNIFILAESLGSV 344 Query: 390 SDHGDQPSPVLLS--YGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVA 439 + PS + + G +V + +RLSVG +V ++ DLKQA+ Sbjct: 345 ESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGI----EDVADLLDDLKQALG 392 >2Z9W-A nrPDB Length = 392 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 24/194 (12%), Positives = 54/194 (27%), Gaps = 29/194 (14%) Query: 154 HLVEEQVAAVTFVPVSKVSGQAEVDDILAAVR--PTTRLVTIMLANNETGIVMPVPEISQ 211 + + + + V + + + ++ P +V++ + +G + P+ I Sbjct: 100 YWAKRYSPHLLEIEV-PYNEAIDPQAVADMLKAHPEITVVSVCHHDTPSGTINPIDAIGA 158 Query: 212 RIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGAL--- 268 + A + DA + G + ED D +K G G Sbjct: 159 LVSA----------HGAYLIVDAVSSFGGMKTHPEDCKADIYVTGPNKCLGAPPGLTMMG 208 Query: 269 -----YIRGL-------GEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNC 316 + + + +++ F P T + I GL A +L Sbjct: 209 VSERAWAKMKANPLAPRASMLSIVDWENAWSRDKPF-PFTPSVSEINGLDVALDLYLNEG 267 Query: 317 EAYEAHMRDVRDYL 330 + Sbjct: 268 PEAVWARHALTAKA 281 >2E54-A nrPDB Length = 385 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 54/295 (18%), Positives = 86/295 (29%), Gaps = 33/295 (11%) Query: 87 GGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHD 146 + F + GTE+N I K+ K H+ G +T Sbjct: 82 NTFGGKVFFANTGTEANEAAIKIARKYGKKKSEKKYRILSAHNSFHGRTLGSLT------ 135 Query: 147 SIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPV 206 + ++ + VP + V+D+ + V + E+GIV Sbjct: 136 ---ATGQPKYQKPFEPL--VPGFEYFEFNNVEDLRRKMSEDVCAVFLEPIQGESGIVPAT 190 Query: 207 PEISQRIKALNQERVAAGLPPILVHTDAAQA----LGKQRVDVEDLGV--DFLTIVGHKF 260 E + + L E A L+ D Q GK + GV D LT Sbjct: 191 KEFLEEARKLCDEYDA------LLVFDEVQCGMGRTGKL-FAYQKYGVVPDVLTTAKGLG 243 Query: 261 YGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQN-CEAY 319 G IGA+ + L P G G AG+ EL + E Sbjct: 244 GGVPIGAVIVNERANV--LEPGDHGT------TFGGNPLACRAGVTVIKELTKEGFLEEV 295 Query: 320 EAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVL 374 E + L+E E + G Q N + + +++ Sbjct: 296 EEKGNYLMKKLQEMKEEYDVVADVRGMGLMIGIQFREEVSNREVATKCFENKLLV 350 >1GC4-A nrPDB Length = 385 Score = 37.2 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 26/79 (32%) Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR 212 E + V + + + + + A+ P T+ + + NN TG V P + Sbjct: 130 EMVRFAGGVVVEVETLPEEGFVPDPERVRRAITPRTKALVVNSPNNPTGAVYPKEVLEAL 189 Query: 213 IKALNQERVAAGLPPILVH 231 + + I H Sbjct: 190 ARLAVEHDFYLVSDEIYEH 208 >1PFF-A nrPDB Length = 331 Score = 36.8 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 60/343 (17%), Positives = 108/343 (31%), Gaps = 45/343 (13%) Query: 111 VKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSK 170 + A + G A H I+ + EH + + V F+ + Sbjct: 13 AEACAATASGMGAIAASVWTFLKAGDHLISDDCLYGCTHALFEHQLRKFGVEVDFIDM-A 71 Query: 171 VSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILV 230 V G +I ++P TR+V N T V+ + + ++ + ILV Sbjct: 72 VPG-----NIEKHLKPNTRIVYFETPANPTLKVIDIEDAVKQARKQKD---------ILV 117 Query: 231 HTDAAQALGKQRVDVEDLGVDFLTIVGHKF---YGPRIGALYIRGLGEFTPLYPM----- 282 D A + DLGVD + K+ + + L + Sbjct: 118 IVDNTFASP-ILTNPLDLGVDIVVHSATKYINGHTDVVAGLVCSRADIIAKVKSQGIKDI 176 Query: 283 ---LFGGGQERNFRPGTENTPMIAG-LGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEF 338 + GT M + A+ V + ++A + L + E Sbjct: 177 TGAIISPHDAWLITRGTLTLDMRVKRAAENAQKVAEFLHEHKAVKKVYYPGLPDHPGHEI 236 Query: 339 GQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSP 398 +K++ + + F + G + VL C V+ +V P+ Sbjct: 237 AKKQMKM---------FGSMIAFDVDGLE-KAKKVLDNCHVVSLAVSLGGPESLIQHPAS 286 Query: 399 VLLSYGVPFDVARNA------LRLSVGRSTTRAEVDLVVQDLK 435 + GVP + A +RLSVG + +D + Q L Sbjct: 287 -MTHAGVPKEEREAAGLTDNLIRLSVGCENVQDIIDDLKQALD 328 >2O0R-A nrPDB Length = 411 Score = 36.0 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 50/155 (32%), Gaps = 25/155 (16%) Query: 92 DIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLP 151 +++ T G TE+ + +V+ + + V A H +T Sbjct: 88 EVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVT----------- 136 Query: 152 LEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQ 211 V VP + D + AV P TR + I +N TG V+ E++ Sbjct: 137 -----------VPLVP-DGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAA 184 Query: 212 RIKALNQERVAAGLPPILVHT--DAAQALGKQRVD 244 + + + H D A+ L D Sbjct: 185 IAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFD 219 >4PIW-A nrPDB Length = 396 Score = 36.0 bits (81), Expect = 0.032, Method: Composition-based stats. Identities = 40/245 (16%), Positives = 69/245 (28%), Gaps = 28/245 (11%) Query: 132 KGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTR-L 190 I + + V A + FV V + + I AA+ TR + Sbjct: 88 IQPGDEVI---MPSYTFVSTANAFVLR-GAKIVFVDVRPDTMNIDETLIEAAITDKTRVI 143 Query: 191 VTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQAL-----GKQRVDV 245 V + A G+ + I K N + V DAAQ + G+ + Sbjct: 144 VPVHYA----GVACEMDTIMALAKKHN----------LFVVEDAAQGVMSTYKGRALGTI 189 Query: 246 EDLGVDFLTIVGHKFY--GPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIA 303 +G + K Y G GA I + G F G + Sbjct: 190 GHIGC--FSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWR 247 Query: 304 GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSI 363 +G + + A + ++RL G LP+ + + Sbjct: 248 DIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCV 307 Query: 364 RGPRL 368 + + Sbjct: 308 QNAHM 312 >3RI6-A nrPDB Length = 430 Score = 35.2 bits (79), Expect = 0.050, Method: Composition-based stats. Identities = 61/442 (13%), Positives = 129/442 (29%), Gaps = 80/442 (18%) Query: 24 KHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLA 83 H + VY D A + + + G + R + + + L Sbjct: 41 VHGALRTPVY-DNAAFE------FENSDEIAQVSLGRALG-HVYSRSSNPTVEDLEQRLK 92 Query: 84 KMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSV 143 + G ++ G + + I ++ + + T+ G S + P F Sbjct: 93 NLTGA--LGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSF----- 145 Query: 144 EHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIV 203 V FV V + + A TT+L+ + +N V Sbjct: 146 ----------------GIEVRFVDV------MDSLAVEHACDETTKLLFLETISNPQLQV 183 Query: 204 MPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGP 263 + +S+ + A I + D ++ + LGVD + KF Sbjct: 184 ADLEALSKVVHAK----------GIPLVVDTTMTPPYL-LEAKRLGVDIEVLSSTKFISG 232 Query: 264 RI----------GALYIRGLGEFTPL------YPMLFGGGQERNFRPGTENTPMIA---- 303 G + L P L+ +E G +P A Sbjct: 233 GGTSVGGVLIDHGLFEWKSLPSLAPYYAKAGPMAFLYKARKEVFQNLGPSLSPHNAYLQS 292 Query: 304 -GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPN-TCNF 361 GL A + ++C+ + + + + + R F Sbjct: 293 LGLETMALRIERSCQNAQELAHWLLSIPQVKCVNHPSLPDSPFYAIAKRQFRYAGSILTF 352 Query: 362 SIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYG-----VPFDVARNALRL 416 + + + +++ + + P V+ + + +++ +RL Sbjct: 353 ELESKEAS-YRFMDALKLIRRATNIHDNKSLILSPYHVIYALNSHEERLKLEISPAMMRL 411 Query: 417 SVGRSTTRAEVDLVVQDLKQAV 438 SVG E++ + +D+ QA+ Sbjct: 412 SVGI----EEIEDLKEDILQAL 429 >6F35-A nrPDB Length = 410 Score = 34.9 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 43/277 (15%), Positives = 91/277 (32%), Gaps = 35/277 (12%) Query: 174 QAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQER---VAAGLPPILV 230 + + + AA+ P TR V + +N +G + ++ L + + + Sbjct: 161 RLTAEKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLEVLLRHPHVWLLVDDMYEHI 220 Query: 231 HTDAAQALGKQRVDVED-LGVDFLTIVG----HKFYGPRIGALYIRGLGEFTPLYPMLFG 285 D + + +E L LT+ G + G RIG Y G E ++ Sbjct: 221 VYDGFRFV--TPAQLEPGLKNRTLTVNGVSKAYAMTGWRIG--YAGGPRELIKAMAVVQ- 275 Query: 286 GGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHL 345 Q + + L + + + E+++ RD + L Sbjct: 276 -SQATSCPSSISQAASVVALNGPQDFLKERTESFQRR----RDLVVNGL----------- 319 Query: 346 NSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGV 405 N+ R+P ++ G V + + + + + V + G Sbjct: 320 NAIDGLDCRVPEGAFYTFSGCAGVLGKVTPSGKRIKTDTDF---CAYLLEDAHVAVVPGS 376 Query: 406 PFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLE 442 F ++ R+S T+ AE+ ++ + A +L Sbjct: 377 AFGLSP-FFRISYA--TSEAELKEALERIAAACDRLS 410 >3NYS-A nrPDB Length = 367 Score = 34.5 bits (77), Expect = 0.086, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 55/177 (31%), Gaps = 43/177 (24%) Query: 63 SPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKG 122 Y G + ++ + LA +G K I + GT++ +V Sbjct: 29 GQYILGPEVTEL----EDRLADFVGAK--YCISCANGTDALQIV---------------- 66 Query: 123 HTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILA 182 + G IT + + + L A +V + + + + A Sbjct: 67 ----QMALGVGPGDEVITPGFTYVATAETVALL----GAKPVYVDIDPRTYNLDPQLLEA 118 Query: 183 AVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALG 239 A+ P T+ ++PV Q + A I V DAAQ+ G Sbjct: 119 AITPRTK------------AIIPVSLYGQ-CADFDAINAIASKYGIPVIEDAAQSFG 162 >4CVQ-A nrPDB Length = 431 Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 3/80 (3%) Query: 160 VAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVP---EISQRIKAL 216 AV ++ ++DDI A + P TR + I+ NN TG V EI + + Sbjct: 167 GKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQH 226 Query: 217 NQERVAAGLPPILVHTDAAQ 236 N A + +++ DA Sbjct: 227 NLIIFADEIYDKILYDDAEH 246 >2QMA-A nrPDB Length = 497 Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 38/93 (40%), Gaps = 7/93 (7%) Query: 94 IFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIR--LP 151 IFTSGGT+SN + + + + + A++ S P K + S H +++ Sbjct: 162 IFTSGGTQSNQMGLM-LARDWIADKLSGHSIQKLGLPDYADKLRIVCSKKSHFTVQKSAS 220 Query: 152 LEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAV 184 L E+ V V + G ++ + + Sbjct: 221 WMGLGEKAVMTVD----ANADGTMDITKLDEVI 249 >6BLG-A nrPDB Length = 379 Score = 33.7 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 37/233 (15%), Positives = 63/233 (27%), Gaps = 28/233 (12%) Query: 132 KGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTR-L 190 I + + V A + FV + + + + I AA+ TR + Sbjct: 71 IQPGDEVI---MPSYTFVSTANAFVLR-GAKIVFVDIRRDTMNIDETLIEAAITDKTRAI 126 Query: 191 VTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQAL-----GKQRVDV 245 V + A ++ A + V DAAQ + G+ + Sbjct: 127 VPVHYA--------------GVACEMDTIMAIADKYNLFVVEDAAQGVMSTYKGRALGTI 172 Query: 246 EDLGVDFLTIVGHKFY--GPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIA 303 +G + K Y G GA I + G F G + Sbjct: 173 GHIGC--FSFHETKNYTAGGEGGATLINDRTLVERAEIIREKGTNRSQFFRGLVDKYTWR 230 Query: 304 GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLP 356 +G + + A + ++RL L G LP Sbjct: 231 DIGSSYLMSDLQAAYLWAQLEAAERINQQRLALWQNYYDALLPLARAGRIELP 283 >1MDZ-A nrPDB Length = 393 Score = 33.7 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 50/343 (14%), Positives = 93/343 (27%), Gaps = 37/343 (10%) Query: 117 NQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAE 176 + + G + G IT S+ S + L A V V + + Sbjct: 61 SSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLL----GANPVMVDVDRDTLMVT 116 Query: 177 VDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQ 236 + I AA+ P T+ + + + + + +R I V DAA Sbjct: 117 PEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGER-------------YGIPVIEDAAH 163 Query: 237 ALG--KQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPM--LFGGG-QERN 291 A G + + G + K G + + +F G G + Sbjct: 164 ATGTSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADKLRSLKFHGLGVDAWD 223 Query: 292 FRP-GTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFP 350 + G + G L N A ++ + R + + F Sbjct: 224 RQSGGRAPQAEVLAPGYKYNLPDLNAAIALAQLQKLDALNARRAAIAAQYHQAMADLPFQ 283 Query: 351 GTQRLPN----------TCNFSIRGPRLQGHVVLAQCRVLMASVGA---ACHSDHGDQPS 397 LP+ + ++A + G A H+ + Sbjct: 284 PL-SLPSWEHIHAWHLFIIRVDEARCGITRDALMASLKTKGIGTGLHFRAAHTQKYYRER 342 Query: 398 PVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQ 440 L+ + L + T ++ D V+ L Q Q Sbjct: 343 FPTLTLPDTEWNSERICSLPLFPDMTESDFDRVITALHQIAGQ 385 >2DGM-A nrPDB Length = 466 Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 33/213 (15%), Positives = 57/213 (26%), Gaps = 17/213 (7%) Query: 152 LEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQ 211 + +P+ + ++ A T V TG E Q Sbjct: 166 WHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNY----EFPQ 221 Query: 212 RIKALNQERVAAGLPPILVHTDAAQA-------LGKQRVDVEDLGVDFLTIVGHKFYGPR 264 + + A I +H DAA D V ++ GHKF Sbjct: 222 PLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAP 281 Query: 265 IGALYIRGLGEFTPLYPMLFG----GGQERNFRPG-TENTPMIAG-LGKAAELVTQNCEA 318 +G ++ E ++F GGQ F + + + L + Sbjct: 282 LGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTK 341 Query: 319 YEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPG 351 + V YL + + + I G Sbjct: 342 VQNASYQVAAYLADEIAKLGPYEFICTGRPDEG 374 >3VOM-A nrPDB Length = 398 Score = 32.5 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 20/62 (32%), Gaps = 11/62 (17%) Query: 193 IMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDF 252 I A+NET + V R G LV DA G VD+ + + Sbjct: 169 IAWAHNETSTGVAVA-----------VRRPEGSDDALVVIDATSGAGGLPVDIAETDAYY 217 Query: 253 LT 254 Sbjct: 218 FA 219 >5TSU-A nrPDB Length = 422 Score = 32.2 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 38/108 (35%), Gaps = 16/108 (14%) Query: 153 EHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR 212 + E ++FV SK + + AA+ P T+LV I N T V +I Sbjct: 139 RQVASEFGLKISFVDCSK------IKLLEAAITPETKLVWIETPTNPT---QKVIDIEGC 189 Query: 213 IKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKF 260 +++ I++ D + + LG D K+ Sbjct: 190 AHIVHKHGD------IILVVDNTFMSPYFQRPLA-LGADISMYSATKY 230 >5W25-A nrPDB Length = 616 Score = 31.8 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 25/54 (46%) Query: 68 GRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSK 121 G AK++ A R LA +G KP D IF S G ++ + + AN+ Sbjct: 380 GPVAKNLTEAERTGLADHVGAKPGDCIFFSAGPVKSSRALLGAARVEIANRLGL 433 >5DDW-A nrPDB Length = 523 Score = 31.8 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 41/151 (27%), Gaps = 24/151 (15%) Query: 304 GLGKAAEL-VTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFS 362 GL + L V + EA + +RLEA R + Sbjct: 379 GLSASIALKVLEMVEADGGRVYQRVRERGQRLEAMLESVRADHSDV-------------- 424 Query: 363 IRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQ-PSPVLLSY--------GVPFDVARNA 413 + G ++ + R + A VL + +P Sbjct: 425 VSAVWGTGLMLALELRDQSNATSQAIREKAAHGFLGYVLAGFLLREHHIRVLPAGPRSGF 484 Query: 414 LRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQ 444 LR S T E+D L+ L DQ Sbjct: 485 LRFSPSLYITDEEIDRTETALRSLFTALRDQ 515 >1ZEJ-A nrPDB Length = 293 Score = 31.4 bits (69), Expect = 0.82, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 2/52 (3%) Query: 158 EQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEI 209 +V +T P+ + VDDI + +R + + N VMP+ EI Sbjct: 93 REVERLTNAPLCSNTSVISVDDIAERLDSPSRFLGVHWMNPP--HVMPLVEI 142 >6G3D-A nrPDB Length = 508 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 22/154 (14%), Positives = 45/154 (29%), Gaps = 4/154 (2%) Query: 9 RDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAG 68 R A A+ G S Y A LEP I A+ A G + + Sbjct: 294 RSRKAAFAAMGPLVGILTSLNAIEYQYSAARVELEPRSIDALIAATHAMTGVVRTLHPNK 353 Query: 69 RKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHA--NQTSKGHTGG 126 + + ++ + + + E++ +V H V+ G Sbjct: 354 ERMRQYAAENYSTMTDLTDMLVRRV--GIDYREAHEIVAHVVITAIEKGIKANKIGLDLV 411 Query: 127 HHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQV 160 + V S+ + P ++++ + Sbjct: 412 QEAAVAQTGAGINVSADDIKDALDPWQNVLRREG 445 >3TEJ-A nrPDB Length = 329 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 14/35 (40%) Query: 244 DVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTP 278 DV+D DF + GH ++ A R + Sbjct: 27 DVQDADADFFALGGHXLLAMKLAAQLSRQVARQVT 61 >2X98-A nrPDB Length = 431 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 38/133 (28%), Gaps = 4/133 (3%) Query: 272 GLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLE 331 P + GGQ R+F N + AA A + V D Sbjct: 147 ARQYIEETQPDVILGGQRRDFEADASNGGTLV---DAARDNGYTIAETAAELDAVDDPPV 203 Query: 332 ERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCR-VLMASVGAACHS 390 L ++ +L+ + PN G L L+ G H+ Sbjct: 204 LGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLSSAGDPDKGFFLLVESGRVDHA 263 Query: 391 DHGDQPSPVLLSY 403 H + P+ V Y Sbjct: 264 GHANYPAQVAEQY 276 >5K8B-A nrPDB Length = 403 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 35/108 (32%), Gaps = 18/108 (16%) Query: 132 KGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLV 191 GA I + + A F + + + I A + P T+ + Sbjct: 74 IGAGDEVIVPPFTFVASVEAIFMA----GAVPIFAEIDETL-CLSPEGIEAVITPRTKAI 128 Query: 192 TIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALG 239 ++ G + + EI K N +++ DA QA+G Sbjct: 129 NLVHM---CGSMAKMDEIKAICKKHN----------LVLLEDACQAIG 163 >4EVZ-A nrPDB Length = 258 Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 37/124 (29%), Gaps = 13/124 (10%) Query: 111 VKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSK 170 V + +GA R + +VE V F+P++ Sbjct: 21 VNFENLRDAGDPVELAARYDEEGADELVFLDITASHEGRETMLEVVERTAEQV-FIPLTV 79 Query: 171 VSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILV 230 G V+D +R V+I N + P + + + G ++V Sbjct: 80 GGGIRSVEDASRLLRAGADKVSI----NTAAVKNP--------ELITEAAEEFGSQAVVV 127 Query: 231 HTDA 234 DA Sbjct: 128 AIDA 131 >5C2Z-A nrPDB Length = 255 Score = 30.6 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 40/111 (36%), Gaps = 8/111 (7%) Query: 35 DYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESL------AKMIGG 88 D+ T P + E+ + + + + + G+ I + ++ A++ Sbjct: 20 DFFKTRPSDSELFSKIQDTTRSPYSSVGTVFVKGKTIATGILIGKNTVITNKHIARLAEN 79 Query: 89 KPQDIIFTSGGT--ESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPH 137 P +IFT G T E + +V + + GG + KP+ Sbjct: 80 DPNKVIFTPGSTRDEGSLVVKKPFGEFIAEEINEAPYGGGTDLSIIKLKPN 130 >5TD7-A nrPDB Length = 678 Score = 30.6 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 32/89 (35%) Query: 298 NTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPN 357 TP I+GLG A + ++ + + ++E KR L++ G + Sbjct: 329 PTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSETNPKRPRLDATNGGPKESSE 388 Query: 358 TCNFSIRGPRLQGHVVLAQCRVLMASVGA 386 + S Q V + + ASV Sbjct: 389 PASESNPKKTAQDIVWPEPLKRMPASVRT 417 >6F77-B nrPDB Length = 400 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 31/207 (14%), Positives = 60/207 (28%), Gaps = 20/207 (9%) Query: 38 ATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFT- 96 A + ++P A+++ E G D A + + +T Sbjct: 7 ALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKKAAIDAIDRGETKYTP 66 Query: 97 -SGGTESNNLVIHSVVKH----FHANQTSKGHTGGHH-----SPVKGAKPHFITSSVEHD 146 SG E + + + A QT G G + + Sbjct: 67 VSGIPELREAIAKKFKRENNLDYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAP--Y 124 Query: 147 SIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPV 206 + P E + V + + + + +D+ A+ P T+ +N +G Sbjct: 125 WVSYP-EMVALCGGTPVFVPTRQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAAYSH 183 Query: 207 PEISQRIKALNQERVAAGLPPILVHTD 233 E+ L + P + V TD Sbjct: 184 EELKALTDVLMKH------PHVWVLTD 204 >3NRA-A nrPDB Length = 407 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 31/98 (31%), Gaps = 1/98 (1%) Query: 120 SKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQV-AAVTFVPVSKVSGQAEVD 178 ++G + ++ + R +E E V + +V + ++ Sbjct: 111 TQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDYVSADETRAGLDLT 170 Query: 179 DILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKAL 216 + A + R+ NN G+V EI Q Sbjct: 171 GLEEAFKAGARVFLFSNPNNPAGVVYSAEEIGQIAALA 208 >2FMU-A nrPDB Length = 248 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 35/85 (41%), Gaps = 3/85 (3%) Query: 177 VDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQ 236 + + + + V I+ A+ ETG V+ + EI + L + G + +A + Sbjct: 13 LPKLREDFKMQNKSVFILGASGETGKVL-LKEI--LGQNLFSKVTLIGRRKLTFEEEAYK 69 Query: 237 ALGKQRVDVEDLGVDFLTIVGHKFY 261 + ++ VD E L V GH Sbjct: 70 NVNQEVVDFEKLDVYASAFQGHDVG 94 >2BKA-A nrPDB Length = 242 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 35/85 (41%), Gaps = 3/85 (3%) Query: 177 VDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQ 236 + + R + V I+ A+ ETG V+ + EI + + L + G + +A + Sbjct: 7 LSKLREDFRMQNKSVFILGASGETGRVL-LKEILE--QGLFSKVTLIGRRKLTFDEEAYK 63 Query: 237 ALGKQRVDVEDLGVDFLTIVGHKFY 261 + ++ VD E L GH Sbjct: 64 NVNQEVVDFEKLDDYASAFQGHDVG 88 >1B9H-A nrPDB Length = 388 Score = 29.1 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 26/80 (32%), Gaps = 4/80 (5%) Query: 132 KGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLV 191 G I + + + A V V + + + + AAV P T+++ Sbjct: 75 VGPGTEVIVPAF----TFISSSQAAQRLGAVTVPVDVDAATYNLDPEAVAAAVTPRTKVI 130 Query: 192 TIMLANNETGIVMPVPEISQ 211 + + + +IS Sbjct: 131 MPVHMAGLMADMDALAKISA 150 >4FAZ-A nrPDB Length = 62 Score = 28.3 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 19/35 (54%) Query: 28 PERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPS 62 P ++Y+ T + VI+ +T+AM EA G P Sbjct: 1 PFAQIYLIEGRTEEQKRAVIEKVTQAMMEAVGAPK 35 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.116 0.286 Lambda K H 0.267 0.0360 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,441,061 Number of Sequences: 36641 Number of extensions: 542977 Number of successful extensions: 1955 Number of sequences better than 10.0: 81 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 1698 Number of HSP's gapped (non-prelim): 123 length of query: 445 length of database: 10,336,785 effective HSP length: 100 effective length of query: 345 effective length of database: 6,672,685 effective search space: 2302076325 effective search space used: 2302076325 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.9 bits)