BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96FX7 (289 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5CCX-A nrPDB 591 e-169 5EQJ-B nrPDB 186 7e-48 1O54-A nrPDB 119 2e-27 3LGA-A nrPDB 96 2e-20 1YB2-A nrPDB 82 3e-16 1I9G-A nrPDB 79 2e-15 2YVL-A nrPDB 67 7e-12 2PWY-A nrPDB 53 1e-07 2B25-A nrPDB 49 2e-06 5X7F-A nrPDB 39 0.003 4O29-A nrPDB 38 0.006 3TFW-A nrPDB 35 0.042 5N5D-A nrPDB 32 0.23 5OQL-R nrPDB 32 0.32 3TMA-A nrPDB 31 0.68 2YXE-A nrPDB 30 1.0 1JG3-A nrPDB 30 1.7 4F4F-A nrPDB 28 3.2 3LBF-A nrPDB 28 3.3 3CJR-A nrPDB 28 3.9 1DL5-A nrPDB 28 5.1 1E6V-A nrPDB 27 7.8 >5CCX-A nrPDB Length = 289 Score = 591 bits (1524), Expect = e-169, Method: Compositional matrix adjust. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60 MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC Sbjct: 1 MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60 Query: 61 GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120 GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA Sbjct: 61 GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120 Query: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL Sbjct: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180 Query: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV Sbjct: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240 Query: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG Sbjct: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 >5EQJ-B nrPDB Length = 383 Score = 186 bits (473), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 105/263 (39%), Positives = 149/263 (56%), Gaps = 28/263 (10%) Query: 3 FVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVT--- 59 F Y++LIKEGD ++ + + VR+ TR+G H D+IG+P+GS++ Sbjct: 6 FSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRYGSFPHK-DIIGKPYGSQIAIRT 64 Query: 60 --CGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSV 117 + +V+VL PTPELWTL+LPHRTQI+Y+ D + I L P S V E+GTGSGS Sbjct: 65 KGSNKFAFVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSF 124 Query: 118 SHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH-RVGRWVTVRTQDVCRSGF------- 169 SHA R++ GHL + EFH R E+A EEF+EH + VT+ +DVC+ GF Sbjct: 125 SHAFARSV---GHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRDVCQGGFLIKKGDT 181 Query: 170 ----------GVSHVADAVFLDIPSPWEAVGHAWDALKV-EGGRFCSFSPCIEQVQRTCQ 218 S A+ VFLD+P+PW+A+ H + V E C FSPCIEQV +T Sbjct: 182 TSYEFGNNETAASLNANVVFLDLPAPWDAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLD 241 Query: 219 ALAARGFSELSTLEVLPQVYNVR 241 L G++++ +E+ + Y R Sbjct: 242 VLEKYGWTDVEMVEIQGRQYESR 264 >1O54-A nrPDB Length = 277 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/278 (27%), Positives = 129/278 (46%), Gaps = 27/278 (9%) Query: 10 IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69 +K GD +LS + V +++ + T G++ + ++ + G + G Y+L Sbjct: 20 LKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGIIDLN-EVFEKGPGEIIRTSAGKKGYIL 78 Query: 70 HPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTG 129 P+ +N+ RTQI+Y D + I MML+++ G + ++G GSG++ + R + +G Sbjct: 79 IPSLIDEIMNMKRRTQIVYPKDSSFIAMMLDVKEGDRIIDTGVGSGAMCAVLARAVGSSG 138 Query: 130 HLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189 + E ++ A+ A + + VT++ +D+ GF V DA+FLD+P PW + Sbjct: 139 KVFAYEKREEFAKLAESNLTKWGLIERVTIKVRDIS-EGFDEKDV-DALFLDVPDPWNYI 196 Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPD 249 W+ALK GGRF + P QVQ T + L F + E L + Y P P+ Sbjct: 197 DKCWEALK-GGGRFATVCPTTNQVQETLKKLQELPFIRIEVWESLFRPYK------PVPE 249 Query: 250 LGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKT 287 P+ V HT Y+ FATK Sbjct: 250 -----------------RLRPVDRMVAHTAYMIFATKV 270 >3LGA-A nrPDB Length = 253 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 77/278 (27%), Positives = 122/278 (43%), Gaps = 26/278 (9%) Query: 9 LIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYV 68 +I+EGD +L G + V + T G+L+ ++IGR FG + +G + Sbjct: 1 MIREGDKVVLVDPRGKRYLITVSK-RDFHTDLGILKLE-EIIGRNFGEAIKSHKGHEFKI 58 Query: 69 LHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128 L P + + QI++ D ALI + PG + E+G GSG+++ + + P Sbjct: 59 LRPRIVDYLDKMKRGPQIVHPKDAALIVAYAGISPGDFIVEAGVGSGALTLFLANIVGPE 118 Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188 G + + E + A+ A E + VT++ +D+ G +V D V LD+P P Sbjct: 119 GRVVSYEIREDFAKLAWENIKWAGFDDRVTIKLKDIY-EGIEEENV-DHVILDLPQPERV 176 Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248 V HA ALK GG F +++PC QV R + L E + P+ NV Sbjct: 177 VEHAAKALK-PGGFFVAYTPCSNQVMRLHEKL-----REFKDYFMKPRTINVLVF----- 225 Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286 D + P A+ HTGY+TFA + Sbjct: 226 ------DQEVKKECM-----RPRTTALVHTGYITFARR 252 >1YB2-A nrPDB Length = 275 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 63/219 (28%), Positives = 94/219 (42%), Gaps = 28/219 (12%) Query: 72 TPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHL 131 +P + + TQI+ D + I M LRPG + E G GSG++S I+ + G L Sbjct: 79 SPMYFGRVIRRNTQIISEIDASYIIMRCGLRPGMDILEVGVGSGNMSSYILYALNGKGTL 138 Query: 132 HTVEFHQQRAEKAREEFQE-HRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVG 190 VE + +KA + E + +G VRT + F + DAV DIP PW V Sbjct: 139 TVVERDEDNLKKAMDNLSEFYDIG---NVRTSRSDIADFISDQMYDAVIADIPDPWNHVQ 195 Query: 191 HAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPDL 250 +K G + P +Q ++T +L+A G L T+E++ + VR Sbjct: 196 KIASMMK-PGSVATFYLPNFDQSEKTVLSLSASGMHHLETVELMKRRILVR--------- 245 Query: 251 GTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 G PA D + HT ++TFA K G Sbjct: 246 -EGATRPASDDLT-------------HTAFITFAIKKSG 270 >1I9G-A nrPDB Length = 280 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 66/239 (27%), Positives = 108/239 (45%), Gaps = 8/239 (3%) Query: 13 GDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPT 72 G+ L+ G + + GA+ T G + H +IG GS V G VL P Sbjct: 10 GERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDA-VIGLEQGSVVKSSNGALFLVLRPL 68 Query: 73 PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLH 132 + +++P Q++Y D A I ++ PG+ V E+G GSG+++ +++R + P G + Sbjct: 69 LVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVI 128 Query: 133 TVEFHQQRAEKAREEFQ---EHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189 + E AE AR W V D+ S V D LD+ +PWE + Sbjct: 129 SYEQRADHAEHARRNVSGCYGQPPDNWRLV-VSDLADSELPDGSV-DRAVLDMLAPWEVL 186 Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARG-FSELSTLEVLPQVYNVRTVSLPP 247 A L V GG + + Q+ R +AL A+ ++E E L + +NV +++ P Sbjct: 187 -DAVSRLLVAGGVLMVYVATVTQLSRIVEALRAKQCWTEPRAWETLQRGWNVVGLAVRP 244 >2YVL-A nrPDB Length = 248 Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 72/280 (25%), Positives = 122/280 (43%), Gaps = 41/280 (14%) Query: 10 IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69 KEG+ ++ G + + + + + + VL+ ++IG+P G K+ G VY Sbjct: 4 FKEGEYVLIRFGEKKFLRKLLPKQSLS-VKKSVLKFD-EVIGKPEGVKIN---GFEVY-- 56 Query: 70 HPT-PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128 PT E+ L +TQI+Y D I + L L V E GTGSG++ A++ +A Sbjct: 57 RPTLEEIILLGFERKTQIIYPKDSFYIALKLNLNKEKRVLEFGTGSGALL-AVLSEVA-- 113 Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGF--GVSHVADAVFLDIPSPW 186 G + T E ++ + A++ ++ +G+ V D + G+ H A F+D+ PW Sbjct: 114 GEVWTFEAVEEFYKTAQKNLKKFNLGKNVKFFNVDFKDAEVPEGIFH---AAFVDVREPW 170 Query: 187 EAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLP 246 + +L +EG P QV + +++ F L +E+L + Y +T+S Sbjct: 171 HYLEKVHKSL-MEGAPVGFLLPTANQVIKLLESI-ENYFGNLEVVEILHRHY--KTIS-- 224 Query: 247 PPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286 FR P + V HT YL F K Sbjct: 225 ----------------ERFR---PEDQMVAHTAYLVFGRK 245 >2PWY-A nrPDB Length = 258 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 79/175 (45%), Gaps = 10/175 (5%) Query: 71 PTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGH 130 PT E + L++ Y D + + +L+L PG V E+GTGSG ++ + R + G Sbjct: 64 PTLEEYLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGL 123 Query: 131 LHTVE---FHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWE 187 + + E H +AE+ F + R+ + ++ D V LD+ PW+ Sbjct: 124 VESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELE----EAAYDGVALDLMEPWK 179 Query: 188 AVGHAWDALKVEGGRF-CSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVR 241 + A AL ++ RF ++ P I QV +A A F LEV + + VR Sbjct: 180 VLEKA--ALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVR 232 >2B25-A nrPDB Length = 336 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 19/198 (9%) Query: 49 LIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVC 108 ++G+ G + G + P E + + + T I + DI +I M+++ PG V Sbjct: 51 IVGKFPGQILRSSFGKQYMLRRPALEDYVVLMKRGTAITFPKDINMILSMMDINPGDTVL 110 Query: 109 ESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-------VGRW---VT 158 E+G+GSG +S + + + G + + E + + A++ ++ R V W V Sbjct: 111 EAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLSHVEEWPDNVD 170 Query: 159 VRTQDVCRSGFGVSHVA-DAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQV---- 213 +D+ + + + DAV LD+ +P + + LK GG + I QV Sbjct: 171 FIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLK-HGGVCAVYVVNITQVIELL 229 Query: 214 --QRTCQ-ALAARGFSEL 228 RTC+ AL+ SE+ Sbjct: 230 DGIRTCELALSCEKISEV 247 >5X7F-A nrPDB Length = 235 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 6/93 (6%) Query: 93 ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152 AL+ ++ +L G V E GTG+G ++ + G L T++ + AR+ F E Sbjct: 68 ALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDIEPEHLRLARQAFAEAG 127 Query: 153 VG----RWVTVRTQDVCRSGFGVSHVADAVFLD 181 +G R ++ R Q+V S+ D VF+D Sbjct: 128 IGPSRTRLISGRAQEVLTRLADASY--DLVFID 158 >4O29-A nrPDB Length = 208 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 10/80 (12%) Query: 77 TLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEF 136 T++ PH +A++ ++E RPG + E GTGSG + I G ++T+E Sbjct: 57 TISAPHM--------VAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYTIEI 108 Query: 137 HQQRAEKAREEFQEHRVGRW 156 ++ A A + + R+G W Sbjct: 109 VKELAVFAAQNLE--RLGYW 126 >3TFW-A nrPDB Length = 248 Score = 35.0 bits (79), Expect = 0.042, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153 + +++ L + E GT G + + R + G L T+E A+ ARE Q V Sbjct: 54 FLALLVRLTQAKRILEIGTLGGYSTIWMARELPADGQLLTLEADAHHAQVARENLQLAGV 113 Query: 154 GRWVTVRTQDVCRS--GFGVSHVADAVFLDIPSP 185 + VT+R +S G D +F+D P Sbjct: 114 DQRVTLREGPALQSLESLGECPAFDLIFIDADKP 147 >5N5D-A nrPDB Length = 226 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 29/64 (45%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153 L+ ++ LR + E GT G S + R + P G L T+E+ + AE A E V Sbjct: 52 LLHLLARLRQARRILEIGTFGGYSSIWLARALPPDGRLVTIEWERSFAESAASRLAEAGV 111 Query: 154 GRWV 157 V Sbjct: 112 AHLV 115 >5OQL-R nrPDB Length = 313 Score = 32.0 bits (71), Expect = 0.32, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 7/129 (5%) Query: 99 LELRPGSVVCESGTGSG-SVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWV 157 + ++PGS V G SG SVSH + + PTG ++ VEF R+ + R Sbjct: 148 IYMKPGSKVLYLGAASGTSVSH-VADIVGPTGAVYAVEF-SHRSGRDLINMATRRTNVIP 205 Query: 158 TVRTQDVCRSGFGVSHVADAVFLDIPSPWEA--VG-HAWDALKVEGGRFCSF-SPCIEQV 213 V + + + D +F D+ P +A VG +A LK GG S + CI+ Sbjct: 206 IVEDARKPMAYRMLVPMVDVIFADVAQPDQARIVGINARLFLKQGGGLLISIKASCIDST 265 Query: 214 QRTCQALAA 222 Q A+ Sbjct: 266 APPEQVFAS 274 >3TMA-A nrPDB Length = 354 Score = 30.8 bits (68), Expect = 0.68, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 28/52 (53%) Query: 95 ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146 + + + RPG V + TGSG+++ T+ PT ++ + ++R ARE Sbjct: 195 LLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLARE 246 >2YXE-A nrPDB Length = 215 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 28/53 (52%) Query: 92 IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKA 144 + ++ +L+L+PG V E GTG G + + G + ++E + AEKA Sbjct: 66 VGMMCELLDLKPGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKA 118 >1JG3-A nrPDB Length = 235 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 10/79 (12%) Query: 71 PTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGH 130 P P T++ PH +A++ + L+PG + E GTGSG + A+I I T Sbjct: 67 PIPAGQTVSAPHM--------VAIMLEIANLKPGMNILEVGTGSGW-NAALISEIVKT-D 116 Query: 131 LHTVEFHQQRAEKAREEFQ 149 ++T+E + E A+ + Sbjct: 117 VYTIERIPELVEFAKRNLE 135 >4F4F-A nrPDB Length = 468 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 18/95 (18%) Query: 195 ALKVEGGRFCSFSPCIEQVQ------RTCQALAARGFSELSTLEVLPQV--YNVRTVSLP 246 AL +EG +F C V+ C AL+ G + ++ ++PQV Y +SL Sbjct: 192 ALSIEG----NFDDCQNLVKGMFNDLEFCDALSLSGVNSINWARIMPQVVYYFTAALSLG 247 Query: 247 PPDLGTGTDGPAGSDTSPF------RSGTPMKEAV 275 PD P G+ F R G P+++ + Sbjct: 248 APDRAVSFTVPTGNFGDIFAGYVAKRMGLPIEQLI 282 >3LBF-A nrPDB Length = 210 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 30/62 (48%) Query: 92 IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH 151 +A +T +LEL P S V E GTGSG + + + + ++ Q +A + + H Sbjct: 66 VARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLH 125 Query: 152 RV 153 V Sbjct: 126 NV 127 >3CJR-A nrPDB Length = 254 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 89 STDIALITMMLELRPGSVVCESGTGSGSVSHA 120 +T +AL + LRPG V + GTGSG ++ A Sbjct: 106 TTRLALKALARHLRPGDKVLDLGTGSGVLAIA 137 >1DL5-A nrPDB Length = 317 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 13/120 (10%) Query: 89 STDIALITMMLE---LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAR 145 S+ +L+ + +E L G V E G G+G + + R + G + +VE+ ++ E A+ Sbjct: 58 SSQPSLMALFMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAK 117 Query: 146 EEFQEHRVGRWVTVRTQDVCRSG-FGVSHVA--DAVFLDIPSPWEAVGHAWDALKVEGGR 202 V R VC G +GV + D +F+ + + V W EGGR Sbjct: 118 -----RNVERLGIENVIFVCGDGYYGVPEFSPYDVIFVTVGV--DEVPETWFTQLKEGGR 170 >1E6V-A nrPDB Length = 553 Score = 27.3 bits (59), Expect = 7.8, Method: Compositional matrix adjust. Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 10/94 (10%) Query: 142 EKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGG 201 EK E Q ++ + + RT VCR V HV D A + W A+++ Sbjct: 188 EKLFPEEQAEQLIKAIGNRTYQVCRMPTIVGHVCDG----------ATMYRWAAMQIAMS 237 Query: 202 RFCSFSPCIEQVQRTCQALAARGFSELSTLEVLP 235 C++ + + A A++ ++ E+LP Sbjct: 238 FICAYKIAAGEAAVSDFAFASKHAEVINMGEMLP 271 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5CCX-A nrPDB 396 e-111 1O54-A nrPDB 298 2e-81 3LGA-A nrPDB 284 2e-77 5EQJ-B nrPDB 278 2e-75 1I9G-A nrPDB 262 1e-70 2YVL-A nrPDB 232 1e-61 2B25-A nrPDB 213 9e-56 2PWY-A nrPDB 211 3e-55 1YB2-A nrPDB 206 6e-54 Sequences not found previously or not previously below threshold: 1DL5-A nrPDB 57 9e-09 2YXE-A nrPDB 54 9e-08 1JG3-A nrPDB 53 1e-07 3TFW-A nrPDB 53 2e-07 4O29-A nrPDB 53 2e-07 3DUW-A nrPDB 49 2e-06 1KR5-A nrPDB 48 4e-06 3MGG-A nrPDB 48 5e-06 5BP7-A nrPDB 48 6e-06 3LBF-A nrPDB 47 9e-06 5X7F-A nrPDB 45 4e-05 1VBF-A nrPDB 44 5e-05 4L7V-A nrPDB 44 6e-05 3BUS-A nrPDB 44 1e-04 3BKX-A nrPDB 44 1e-04 5N5D-A nrPDB 43 1e-04 1YUB-A nrPDB 43 1e-04 3CCF-A nrPDB 43 2e-04 1NKV-A nrPDB 43 2e-04 5EKU-A nrPDB 41 6e-04 4M36-A nrPDB 41 6e-04 3E05-A nrPDB 41 7e-04 3EEY-A nrPDB 41 8e-04 1UWV-A nrPDB 40 0.001 3M6U-A nrPDB 40 0.001 3TMA-A nrPDB 40 0.001 2IPX-A nrPDB 40 0.001 1R18-A nrPDB 40 0.001 2PBF-A nrPDB 39 0.002 3DLC-A nrPDB 39 0.003 5BXY-A nrPDB 39 0.003 3R3H-A nrPDB 39 0.003 6EC3-A nrPDB 38 0.004 5LOG-A nrPDB 38 0.004 6BQC-A nrPDB 38 0.004 3HM2-A nrPDB 38 0.006 2PXX-A nrPDB 38 0.006 2HNK-A nrPDB 37 0.009 2AS0-A nrPDB 37 0.011 4INE-A nrPDB 37 0.011 4OA5-A nrPDB 37 0.012 4DF3-A nrPDB 36 0.014 5WYK-3B nrPDB 36 0.015 3C3P-A nrPDB 36 0.016 5EVJ-A nrPDB 36 0.017 3M4X-A nrPDB 36 0.017 5OQL-R nrPDB 36 0.018 3CBG-A nrPDB 36 0.021 4KDR-A nrPDB 36 0.023 3VC2-A nrPDB 36 0.026 3R9X-B nrPDB 36 0.026 4PON-A nrPDB 35 0.032 1SQG-A nrPDB 35 0.034 1QAM-A nrPDB 35 0.037 3EVZ-A nrPDB 34 0.061 6IFX-A nrPDB 34 0.062 5YLN-A nrPDB 34 0.062 3NJR-A nrPDB 34 0.068 2VS1-A nrPDB 34 0.071 2B3T-A nrPDB 34 0.071 3D2L-A nrPDB 34 0.097 6IFV-A nrPDB 33 0.11 3R0Q-C nrPDB 33 0.12 1ZQ9-A nrPDB 33 0.14 1EIZ-A nrPDB 33 0.20 2NNW-B nrPDB 33 0.22 4FZV-A nrPDB 33 0.23 2YXD-A nrPDB 33 0.23 4KDC-A nrPDB 32 0.28 5WWT-A nrPDB 31 0.44 3DMF-A nrPDB 31 0.45 4F86-A nrPDB 31 0.49 4FS8-A nrPDB 31 0.55 5WP5-A nrPDB 31 0.56 5FUB-A nrPDB 31 0.61 3CJR-A nrPDB 31 0.88 4DZR-A nrPDB 30 0.96 3E23-A nrPDB 30 1.0 6H1E-A nrPDB 30 1.3 4JJI-A nrPDB 30 1.5 1TPY-A nrPDB 29 2.1 1VQ1-A nrPDB 29 2.6 3W53-A nrPDB 29 3.3 1F8F-A nrPDB 29 3.3 5TNX-A nrPDB 28 4.0 >5CCX-A nrPDB Length = 289 Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60 MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC Sbjct: 1 MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60 Query: 61 GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120 GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA Sbjct: 61 GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120 Query: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL Sbjct: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180 Query: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV Sbjct: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240 Query: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG Sbjct: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 >1O54-A nrPDB Length = 277 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 77/280 (27%), Positives = 130/280 (46%), Gaps = 27/280 (9%) Query: 8 ELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVY 67 + +K GD +LS + V +++ + T G++ + ++ + G + G Y Sbjct: 18 DTLKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGIIDLN-EVFEKGPGEIIRTSAGKKGY 76 Query: 68 VLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAP 127 +L P+ +N+ RTQI+Y D + I MML+++ G + ++G GSG++ + R + Sbjct: 77 ILIPSLIDEIMNMKRRTQIVYPKDSSFIAMMLDVKEGDRIIDTGVGSGAMCAVLARAVGS 136 Query: 128 TGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWE 187 +G + E ++ A+ A + + VT++ +D+ GF V DA+FLD+P PW Sbjct: 137 SGKVFAYEKREEFAKLAESNLTKWGLIERVTIKVRDIS-EGFDEKDV-DALFLDVPDPWN 194 Query: 188 AVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPP 247 + W+ALK GGRF + P QVQ T + L F + E L + Y P Sbjct: 195 YIDKCWEALK-GGGRFATVCPTTNQVQETLKKLQELPFIRIEVWESLFRPYK------PV 247 Query: 248 PDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKT 287 P+ P+ V HT Y+ FATK Sbjct: 248 PE-----------------RLRPVDRMVAHTAYMIFATKV 270 >3LGA-A nrPDB Length = 253 Score = 284 bits (727), Expect = 2e-77, Method: Composition-based stats. Identities = 77/279 (27%), Positives = 122/279 (43%), Gaps = 26/279 (9%) Query: 9 LIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYV 68 +I+EGD +L G + V + T G+L+ ++IGR FG + +G + Sbjct: 1 MIREGDKVVLVDPRGKRYLITVSK-RDFHTDLGILKLE-EIIGRNFGEAIKSHKGHEFKI 58 Query: 69 LHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128 L P + + QI++ D ALI + PG + E+G GSG+++ + + P Sbjct: 59 LRPRIVDYLDKMKRGPQIVHPKDAALIVAYAGISPGDFIVEAGVGSGALTLFLANIVGPE 118 Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188 G + + E + A+ A E + VT++ +D+ G +V D V LD+P P Sbjct: 119 GRVVSYEIREDFAKLAWENIKWAGFDDRVTIKLKDIY-EGIEEENV-DHVILDLPQPERV 176 Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248 V HA ALK GG F +++PC QV R + L E + P+ NV Sbjct: 177 VEHAAKALK-PGGFFVAYTPCSNQVMRLHEKL-----REFKDYFMKPRTINVLVF----- 225 Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKT 287 D + P A+ HTGY+TFA + Sbjct: 226 ------DQEVKKECM-----RPRTTALVHTGYITFARRI 253 >5EQJ-B nrPDB Length = 383 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 105/263 (39%), Positives = 149/263 (56%), Gaps = 28/263 (10%) Query: 3 FVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVT--- 59 F Y++LIKEGD ++ + + VR+ TR+G H D+IG+P+GS++ Sbjct: 6 FSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRYGSFPHK-DIIGKPYGSQIAIRT 64 Query: 60 --CGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSV 117 + +V+VL PTPELWTL+LPHRTQI+Y+ D + I L P S V E+GTGSGS Sbjct: 65 KGSNKFAFVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSF 124 Query: 118 SHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-VGRWVTVRTQDVCRSGF------- 169 SHA R++ GHL + EFH R E+A EEF+EH + VT+ +DVC+ GF Sbjct: 125 SHAFARSV---GHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRDVCQGGFLIKKGDT 181 Query: 170 ----------GVSHVADAVFLDIPSPWEAVGHAWDALKV-EGGRFCSFSPCIEQVQRTCQ 218 S A+ VFLD+P+PW+A+ H + V E C FSPCIEQV +T Sbjct: 182 TSYEFGNNETAASLNANVVFLDLPAPWDAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLD 241 Query: 219 ALAARGFSELSTLEVLPQVYNVR 241 L G++++ +E+ + Y R Sbjct: 242 VLEKYGWTDVEMVEIQGRQYESR 264 >1I9G-A nrPDB Length = 280 Score = 262 bits (668), Expect = 1e-70, Method: Composition-based stats. Identities = 70/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%) Query: 13 GDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPT 72 G+ L+ G + + GA+ T G + H +IG GS V G VL P Sbjct: 10 GERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDA-VIGLEQGSVVKSSNGALFLVLRPL 68 Query: 73 PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLH 132 + +++P Q++Y D A I ++ PG+ V E+G GSG+++ +++R + P G + Sbjct: 69 LVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVI 128 Query: 133 TVEFHQQRAEKAREEFQ---EHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189 + E AE AR W V D+ S V D LD+ +PWE + Sbjct: 129 SYEQRADHAEHARRNVSGCYGQPPDNWRLV-VSDLADSELPDGSV-DRAVLDMLAPWEVL 186 Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARG-FSELSTLEVLPQVYNVRTVSLPPP 248 A L V GG + + Q+ R +AL A+ ++E E L + +NV +++ Sbjct: 187 D-AVSRLLVAGGVLMVYVATVTQLSRIVEALRAKQCWTEPRAWETLQRGWNVVGLAV--- 242 Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286 P GHT +L + Sbjct: 243 --------------------RPQHSMRGHTAFLVATRR 260 >2YVL-A nrPDB Length = 248 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 66/278 (23%), Positives = 114/278 (41%), Gaps = 37/278 (13%) Query: 10 IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69 KEG+ ++ G + + + + + + VL+ ++IG+P G K+ G VY Sbjct: 4 FKEGEYVLIRFGEKKFLRKLLPKQSLS-VKKSVLKFD-EVIGKPEGVKIN---GFEVY-- 56 Query: 70 HPTPELW-TLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128 PT E L +TQI+Y D I + L L V E GTGSG++ A++ +A Sbjct: 57 RPTLEEIILLGFERKTQIIYPKDSFYIALKLNLNKEKRVLEFGTGSGAL-LAVLSEVA-- 113 Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188 G + T E ++ + A++ ++ +G+ V D + + A F+D+ PW Sbjct: 114 GEVWTFEAVEEFYKTAQKNLKKFNLGKNVKFFNVDFKDAEVPEG-IFHAAFVDVREPWHY 172 Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248 + +L +EG P QV + +++ F L +E+L + Y Sbjct: 173 LEKVHKSL-MEGAPVGFLLPTANQVIKLLESIE-NYFGNLEVVEILHRHYK--------- 221 Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286 + P + V HT YL F K Sbjct: 222 --------------TISERFRPEDQMVAHTAYLVFGRK 245 >2B25-A nrPDB Length = 336 Score = 213 bits (541), Expect = 9e-56, Method: Composition-based stats. Identities = 52/255 (20%), Positives = 100/255 (39%), Gaps = 18/255 (7%) Query: 2 SFVAYEELIKEGDTAILSLGHGA---MVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKV 58 S + E + G+ + G G R+ + G + ++G+ G + Sbjct: 2 SSTSRERPFQAGELILAETGEGETKFKKLFRLNNFGLLNSNWGAVPF-GKIVGKFPGQIL 60 Query: 59 TCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVS 118 G + P E + + + T I + DI +I M+++ PG V E+G+GSG +S Sbjct: 61 RSSFGKQYMLRRPALEDYVVLMKRGTAITFPKDINMILSMMDINPGDTVLEAGSGSGGMS 120 Query: 119 HAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-------VGRW---VTVRTQDVCRSG 168 + + + G + + E + + A++ ++ R V W V +D+ + Sbjct: 121 LFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLSHVEEWPDNVDFIHKDISGAT 180 Query: 169 FGVSHVA-DAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALA--ARGF 225 + + DAV LD+ +P + + LK GG + I QV + Sbjct: 181 EDIKSLTFDAVALDMLNPHVTLPVFYPHLK-HGGVCAVYVVNITQVIELLDGIRTCELAL 239 Query: 226 SELSTLEVLPQVYNV 240 S EV+ + + V Sbjct: 240 SCEKISEVIVRDWLV 254 >2PWY-A nrPDB Length = 258 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 65/277 (23%), Positives = 100/277 (36%), Gaps = 32/277 (11%) Query: 16 AILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPEL 75 +L G V + G G + H L+ G V G + V PT E Sbjct: 10 LLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEA-LLEAGPGGVVRTHLGEELSVHRPTLEE 68 Query: 76 WTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVE 135 + L++ Y D + + +L+L PG V E+GTGSG ++ + R + G + + E Sbjct: 69 YLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYE 128 Query: 136 ---FHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHA 192 H +AE+ F + R+ + D V LD+ PW+ + A Sbjct: 129 ARPHHLAQAERNVRAFWQVENVRFHLGKL----EEAELEEAAYDGVALDLMEPWKVLEKA 184 Query: 193 WDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPDLGT 252 ALK ++ P I QV +A A F LEV + + VR Sbjct: 185 ALALK-PDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVR----------- 232 Query: 253 GTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 P + VGHT +L + G Sbjct: 233 ------------LPVAHPRFQQVGHTAFLVALRRWKG 257 >1YB2-A nrPDB Length = 275 Score = 206 bits (525), Expect = 6e-54, Method: Composition-based stats. Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 29/238 (12%) Query: 53 PFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGT 112 G ++ G V +P + + TQI+ D + I M LRPG + E G Sbjct: 61 EPGDELIVS-GKSFIVSDFSPMYFGRVIRRNTQIISEIDASYIIMRCGLRPGMDILEVGV 119 Query: 113 GSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE-HRVGRWVTVRTQDVCRSGFGV 171 GSG++S I+ + G L VE + +KA + E + +G VRT + F Sbjct: 120 GSGNMSSYILYALNGKGTLTVVERDEDNLKKAMDNLSEFYDIG---NVRTSRSDIADFIS 176 Query: 172 SHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTL 231 + DAV DIP PW V +K G + P +Q ++T +L+A G L T+ Sbjct: 177 DQMYDAVIADIPDPWNHVQKIASMMK-PGSVATFYLPNFDQSEKTVLSLSASGMHHLETV 235 Query: 232 EVLPQVYNVRTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289 E++ + VR G PA D + HT ++TFA K G Sbjct: 236 ELMKRRILVR----------EGATRPASDDLT-------------HTAFITFAIKKSG 270 >1DL5-A nrPDB Length = 317 Score = 57.2 bits (136), Expect = 9e-09, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 58/171 (33%), Gaps = 12/171 (7%) Query: 39 RHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNL----PHRTQILYSTDIAL 94 ++GV H I + F Y L E L + + +AL Sbjct: 11 KYGVSDH----IAKAFLEIPREEFLTKSYPLSYVYEDIVLVSYDDGEEYSTSSQPSLMAL 66 Query: 95 ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG 154 + L G V E G G+G + + R + G + +VE+ ++ E A+ + + Sbjct: 67 FMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGI- 125 Query: 155 RWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCS 205 V D G D +F+ + + V W EGGR Sbjct: 126 ENVIFVCGDGYY-GVPEFSPYDVIFVTVGV--DEVPETWFTQLKEGGRVIV 173 >2YXE-A nrPDB Length = 215 Score = 53.7 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 56/174 (32%), Gaps = 18/174 (10%) Query: 58 VTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIAL------------ITMMLELRPGS 105 + R + P E +L + +I + +L+L+PG Sbjct: 20 IKSKRVIDALLKVPREEFLPEHLKEYAYVDTPLEIGYGQTISAIHMVGMMCELLDLKPGM 79 Query: 106 VVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVC 165 V E GTG G + + G + ++E + AEKA ++ V V D Sbjct: 80 KVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRKLGYD-NVIVIVGDGT 138 Query: 166 RSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQA 219 G+ D ++ P + LK G P +QR A Sbjct: 139 L-GYEPLAPYDRIYTTAAGP-KIPEPLIRQLKDGGKLLM---PVGRYLQRLVLA 187 >1JG3-A nrPDB Length = 235 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 52/127 (40%), Gaps = 5/127 (3%) Query: 74 ELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT 133 L +P + +A++ + L+PG + E GTGSG + I + ++T Sbjct: 62 IDEPLPIPAGQTVSAPHMVAIMLEIANLKPGMNILEVGTGSGWNAALISEIV--KTDVYT 119 Query: 134 VEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAW 193 +E + E A+ + V + V V D + GF D + + +P + Sbjct: 120 IERIPELVEFAKRNLERAGV-KNVHVILGDGSK-GFPPKAPYDVIIVTAGAP-KIPEPLI 176 Query: 194 DALKVEG 200 + LK+ G Sbjct: 177 EQLKIGG 183 >3TFW-A nrPDB Length = 248 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 2/94 (2%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153 + +++ L + E GT G + + R + G L T+E A+ ARE Q V Sbjct: 54 FLALLVRLTQAKRILEIGTLGGYSTIWMARELPADGQLLTLEADAHHAQVARENLQLAGV 113 Query: 154 GRWVTVRTQDV--CRSGFGVSHVADAVFLDIPSP 185 + VT+R G D +F+D P Sbjct: 114 DQRVTLREGPALQSLESLGECPAFDLIFIDADKP 147 >4O29-A nrPDB Length = 208 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 5/151 (3%) Query: 74 ELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT 133 E L L I +A++ ++E RPG + E GTGSG + I G ++T Sbjct: 46 EDRPLPLFAGATISAPHMVAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYT 105 Query: 134 VEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAW 193 +E ++ A A + + V V D + G DA+ + + + + A Sbjct: 106 IEIVKELAVFAAQNLERLGYWGVVEVYHGDGKK-GLEKHAPFDAIIVTAAA--DVIPPAL 162 Query: 194 DALKVEGGRFCSFSPCIEQVQRTCQALAARG 224 +GG P E++ + + RG Sbjct: 163 IRQLKDGGVMV--IPVEERLGQVLYKVVKRG 191 >3DUW-A nrPDB Length = 223 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 36/75 (48%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146 + T + ++++++ + E GT G + + R ++ G + T+E ++ A+ AR Sbjct: 42 VSPTQGKFLQLLVQIQGARNILEIGTLGGYSTIWLARGLSSGGRVVTLEASEKHADIARS 101 Query: 147 EFQEHRVGRWVTVRT 161 + + V VRT Sbjct: 102 NIERANLNDRVEVRT 116 >1KR5-A nrPDB Length = 226 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 44/126 (34%), Gaps = 7/126 (5%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 L G+ + G+GSG ++ R + TG + ++ ++ + + ++ + R Sbjct: 75 LHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPTLLSSGR 134 Query: 161 TQDVCRS---GFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFS--PCIEQVQR 215 Q V G+ DA+ + +P V A GGR Q+ Sbjct: 135 VQLVVGDGRMGYAEEAPYDAIHVGAAAP--VVPQALIDQLKPGGRLILPVGPAGGNQMLE 192 Query: 216 TCQALA 221 L Sbjct: 193 QYDKLQ 198 >3MGG-A nrPDB Length = 276 Score = 47.9 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 8/103 (7%) Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQ 162 PG+ V E+G G G+ + + + P + +++ + EKARE +++ + + V Sbjct: 37 PGAKVLEAGCGIGAQTVILAKN-NPDAEITSIDISPESLEKARENTEKNGI-KNVKFLQA 94 Query: 163 DVCRSGFGVSHVADAVFL-----DIPSPWEAVGHAWDALKVEG 200 ++ F S D +F+ + SP EA+ LK G Sbjct: 95 NIFSLPFEDSS-FDHIFVCFVLEHLQSPEEALKSLKKVLKPGG 136 >5BP7-A nrPDB Length = 271 Score = 47.5 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 38/224 (16%), Positives = 63/224 (28%), Gaps = 18/224 (8%) Query: 64 GWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIR 123 + P T + + + + L L PG+ V + G+GSG + R Sbjct: 20 FQSMLDIPRIFTITESAHRIHNPITPEKLTTLGAALRLEPGTRVLDLGSGSGEMLCTWAR 79 Query: 124 TIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183 G ++ Q +A+ +E V VT D V + Sbjct: 80 DHGIIGT--GIDMSQLFTAQAKLRAEELGVADRVTFIHGDASGYVSDDKA---GVAACVG 134 Query: 184 SPW------EAVGHAWDALKVEGGRFCS-----FSPCIEQVQRTCQALAARGF-SELSTL 231 + W + +L+ G P E V R C A + F L Sbjct: 135 ATWIGGGVAGTIELLARSLRPGGIILIGEPYWRQVPPTEDVARGCLANSTSDFLMLPELL 194 Query: 232 EVLPQ-VYNVRTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEA 274 + Y+V + L D + + P E Sbjct: 195 ASFGRLGYDVVEMVLADQDGWDRYEAAKWLTMRRWLEANPDDEL 238 >3LBF-A nrPDB Length = 210 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 33/141 (23%), Positives = 54/141 (38%), Gaps = 7/141 (4%) Query: 78 LNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFH 137 L + I +A +T +LEL P S V E GTGSG + + + H+ +VE Sbjct: 52 LPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQ---HVCSVERI 108 Query: 138 QQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALK 197 + +AR + + V+ R D + G+ DA+ + P + A Sbjct: 109 KGLQWQARRRLKNLDL-HNVSTRHGDGWQ-GWQARAPFDAIIVTAAPPE--IPTALMTQL 164 Query: 198 VEGGRFCSFSPCIEQVQRTCQ 218 EGG Q + + Sbjct: 165 DEGGILVLPVGEEHQYLKRVR 185 >5X7F-A nrPDB Length = 235 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 48/134 (35%), Gaps = 9/134 (6%) Query: 81 PHRTQI----LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEF 136 T I + AL+ ++ +L G V E GTG+G ++ + G L T++ Sbjct: 52 ERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDI 111 Query: 137 HQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFG--VSHVADAVFLDIPSPWEAVGHAWD 194 + AR+ F E +G T + D VF+D P + + + Sbjct: 112 EPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDA-DPIDQPDYVAE 170 Query: 195 --ALKVEGGRFCSF 206 L GG Sbjct: 171 GVRLLRSGGVIVVH 184 >1VBF-A nrPDB Length = 231 Score = 44.4 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 52/146 (35%), Gaps = 11/146 (7%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153 + L+L G V E GTG G + I + + +VE +++ A + + Sbjct: 61 FMLDELDLHKGQKVLEIGTGIGYYTALIAEIVD---KVVSVEINEKMYNYASKLLSYY-- 115 Query: 154 GRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQV 213 + + D G+ D V + +P + ++ LK G + +V Sbjct: 116 -NNIKLILGDGTL-GYEEEKPYDRVVVWATAP-TLLCKPYEQLKEGG--IMILPIGVGRV 170 Query: 214 QRTCQALAARGFSELSTL-EVLPQVY 238 Q+ + + L L EV+ Sbjct: 171 QKLYKVIKKGNSPSLENLGEVMFGRI 196 >4L7V-A nrPDB Length = 225 Score = 44.4 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 78 LNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFH 137 L + I +A +T +L L P + V E GTGSG + + + + H+ TVE Sbjct: 67 LPIGQGQTISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVN---HVFTVERI 123 Query: 138 QQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180 + A+ ++ + V+ + D + G+ DA+ + Sbjct: 124 KTLQWDAKRRLKQLDI-YNVSTKHGDGWQ-GWPARGPFDAILV 164 >3BUS-A nrPDB Length = 273 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 35/225 (15%), Positives = 62/225 (27%), Gaps = 35/225 (15%) Query: 95 ITMMLELRPGSVVCESGTGSG--SVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152 + +L++R G V + G G G +V A R + + + + + +A Sbjct: 53 MIALLDVRSGDRVLDVGCGIGKPAVRLATARDV----RVTGISISRPQVNQANARATAAG 108 Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFLD----IPSPWEAVGHAWDALKVEGGR----FC 204 + VT D F + L+ +P A+ L+ G F Sbjct: 109 LANRVTFSYADAMDLPFEDASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIADFV 168 Query: 205 SFSPCIEQVQRTCQALAARG----FSELSTLEVLPQVYNVRTVSL--------PPPDLGT 252 +P + A A G + E + + S P Sbjct: 169 LLAPVEGAKKEAVDAFRAGGGVLSLGGIDEYESDVRQAELVVTSTVDISAQARPSLVKTA 228 Query: 253 GTDGPAGSDTSPFRSGTPMKEAVG---------HTGYLTFATKTP 288 A S PF + + GY+ + P Sbjct: 229 EAFENARSQVEPFMGAEGLDRMIATFRGLAEVPEAGYVLIGARKP 273 >3BKX-A nrPDB Length = 275 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 32/95 (33%), Gaps = 8/95 (8%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRA------EKAREE 147 I +++PG + E G G G +S + + +GH+ ++ +A Sbjct: 34 AIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTLGQAWNH 93 Query: 148 FQEHRVGRWVT--VRTQDVCRSGFGVSHVADAVFL 180 +G +T T G D V L Sbjct: 94 LLAGPLGDRLTVHFNTNLSDDLGPIADQHFDRVVL 128 >5N5D-A nrPDB Length = 226 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146 + + L+ ++ LR + E GT G S + R + P G L T+E+ + AE A Sbjct: 45 VSAPQGKLLHLLARLRQARRILEIGTFGGYSSIWLARALPPDGRLVTIEWERSFAESAAS 104 Query: 147 EFQEHRV---GRWVTVRTQDVCRS-GFGVSHVADAVFLDIPSP 185 E V R D+ + + D VF+D P Sbjct: 105 RLAEAGVAHLVEQHVGRALDILPTLDRPGTAPFDMVFVDANKP 147 >1YUB-A nrPDB Length = 245 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 35/93 (37%), Gaps = 6/93 (6%) Query: 86 ILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAR 145 + + I L L+ V E GTG G ++ + + + + ++E + Sbjct: 12 LTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKI---SKQVTSIELDSHLFNLSS 68 Query: 146 EEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAV 178 E+ + + VT+ QD+ + F V Sbjct: 69 EKLK---LNTRVTLIHQDILQFQFPNKQRYKIV 98 >3CCF-A nrPDB Length = 279 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 48/142 (33%), Gaps = 13/142 (9%) Query: 95 ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQ--EHR 152 + +L +PG + + G G+G ++ I + + + EKAR+ + Sbjct: 49 LLQLLNPQPGEFILDLGCGTGQLTEKIAQ---SGAEVLGTDNAATMIEKARQNYPHLHFD 105 Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSF--SPCI 210 V R + F ++A+ + P A+ ALK G F I Sbjct: 106 VADARNFRVDKPLDAVF-----SNAMLHWVKEPEAAIASIHQALKSGGRFVAEFGGKGNI 160 Query: 211 EQVQRTC-QALAARGFSELSTL 231 + + AL G L Sbjct: 161 KYILEALYNALETLGIHNPQAL 182 >1NKV-A nrPDB Length = 256 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 52/143 (36%), Gaps = 12/143 (8%) Query: 99 LELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVT 158 L ++PG+ + + G+GSG + R TG ++ +A+ +E V V Sbjct: 32 LRMKPGTRILDLGSGSGEMLCTWARDHGITGT--GIDMSSLFTAQAKRRAEELGVSERVH 89 Query: 159 VRTQDVCRSGFGVSHVADAVFLDIPSPW------EAVGHAWDALKVEGGRFCSFSPCIEQ 212 D +G+ + D + + W A +LK GG P Q Sbjct: 90 FIHNDA--AGYVANEKCDVAAC-VGATWIAGGFAGAEELLAQSLK-PGGIMLIGEPYWRQ 145 Query: 213 VQRTCQALAARGFSELSTLEVLP 235 + T + A G S S LP Sbjct: 146 LPATEEIAQACGVSSTSDFLTLP 168 >5EKU-A nrPDB Length = 390 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 2/68 (2%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153 + + P + V E G GSG +S + + VE ++ A+ ARE + + + Sbjct: 86 YEVLKKHVTPETGVLEIGAGSGLLSLMAAKL--GAKWVVAVEGSEELAKLARENIRANNM 143 Query: 154 GRWVTVRT 161 V V Sbjct: 144 EHQVKVLH 151 >4M36-A nrPDB Length = 343 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 2/68 (2%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153 + + P + V E G GSG +S + + VE ++ A+ ARE + + + Sbjct: 51 YEVLKKHVTPETGVLEIGAGSGLLSLMAAKL--GAKWVVAVEGSEELAKLARENIRANNM 108 Query: 154 GRWVTVRT 161 V V Sbjct: 109 EHQVKVLH 116 >3E05-A nrPDB Length = 204 Score = 40.6 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 10/137 (7%) Query: 93 ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152 A+ L L+ V+ + G GS SVS + P G + +E + Q R+ ++ Sbjct: 30 AVTLSKLRLQDDLVMWDIGAGSASVSIE-ASNLMPNGRIFALERNPQYLGFIRDNLKKF- 87 Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFL----DIPSPWEAVGHAWDALKVEGGRFCSFSP 208 V R VT+ + G D VF+ + E + LK EG + Sbjct: 88 VARNVTL-VEAFAPEGLDDLPDPDRVFIGGSGGMLE--EIIDAVDRRLKSEG-VIVLNAV 143 Query: 209 CIEQVQRTCQALAARGF 225 ++ + + + L G+ Sbjct: 144 TLDTLTKAVEFLEDHGY 160 >3EEY-A nrPDB Length = 197 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 7/63 (11%), Positives = 25/63 (39%) Query: 98 MLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWV 157 + ++ G V ++ G+G+ + + + G + + + ++ + + V Sbjct: 17 KMFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRV 76 Query: 158 TVR 160 T+ Sbjct: 77 TLI 79 >1UWV-A nrPDB Length = 433 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 52/131 (39%), Gaps = 8/131 (6%) Query: 99 LELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVT 158 L+++P V + G G+ + + A + VE EK ++ + + + + VT Sbjct: 282 LDVQPEDRVLDLFCGMGNFTLPLATQAAS---VVGVEGVPALVEKGQQNARLNGL-QNVT 337 Query: 159 VRTQDVCRSGFG---VSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQR 215 +++ + D V LD P+ A G +K+E R S + R Sbjct: 338 FYHENLEEDVTKQPWAKNGFDKVLLD-PARAGAAGVMQQIIKLEPIRIVYVSCNPATLAR 396 Query: 216 TCQALAARGFS 226 +AL G++ Sbjct: 397 DSEALLKAGYT 407 >3M6U-A nrPDB Length = 464 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 30/97 (30%), Gaps = 2/97 (2%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146 + + ++L+ +PG V + G + + + G L E +R E Sbjct: 85 IQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLANEVDGKRVRGLLE 144 Query: 147 EFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183 + VT FG V LD P Sbjct: 145 NVERWGAPLAVTQAPPRALAEAFGTY--FHRVLLDAP 179 >3TMA-A nrPDB Length = 354 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 28/59 (47%) Query: 89 STDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147 + + + RPG V + TGSG+++ T+ PT ++ + ++R ARE Sbjct: 189 PVLAQALLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLAREA 247 >2IPX-A nrPDB Length = 233 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 53/160 (33%), Gaps = 4/160 (2%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 ++PG+ V G SG+ + + P G ++ VEF R+ + + R + Sbjct: 75 IKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSH-RSGRDLINLAKKRTNIIPVIE 133 Query: 161 TQDVCRSGFGVSHVADAVFLDIPSPWE---AVGHAWDALKVEGGRFCSFSPCIEQVQRTC 217 + + D +F D+ P + +A L+ G S + Sbjct: 134 DARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASA 193 Query: 218 QALAARGFSELSTLEVLPQVYNVRTVSLPPPDLGTGTDGP 257 +A+ A ++ + PQ + G P Sbjct: 194 EAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRP 233 >1R18-A nrPDB Length = 227 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 37/93 (39%), Gaps = 8/93 (8%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTG-----HLHTVEFHQQRAEKAREEFQEHR--- 152 L+PG+ + + G+GSG ++ R I G + +E + +++ Sbjct: 82 LKPGARILDVGSGSGYLTACFYRYIKAKGVDADTRIVGIEHQAELVRRSKANLNTDDRSM 141 Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSP 185 + + + R G+ + +A+ + +P Sbjct: 142 LDSGQLLIVEGDGRKGYPPNAPYNAIHVGAAAP 174 >2PBF-A nrPDB Length = 227 Score = 39.1 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 21/144 (14%), Positives = 49/144 (34%), Gaps = 17/144 (11%) Query: 39 RHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMM 98 R G++ D+ + + + RG Y+ + + H I AL Sbjct: 21 RRGIID-DDDV----YNTMLQVDRGK--YIKEIPYIDTPVYISHGVTISAPHMHALSLKR 73 Query: 99 L--ELRPGSVVCESGTGSGSVSHAIIRTI----APTGHLHTVEFHQQRAEKAREEFQEHR 152 L L+PGS + G+GSG ++ + + ++ +E + + E + + Sbjct: 74 LINVLKPGSRAIDVGSGSGYLTVCMAIKMNVLENKNSYVIGLERVKDLVNFSLENIKRDK 133 Query: 153 VG----RWVTVRTQDVCRSGFGVS 172 + +++ + Sbjct: 134 PELLKIDNFKIIHKNIYQVNEEEK 157 >3DLC-A nrPDB Length = 219 Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 27/80 (33%), Gaps = 3/80 (3%) Query: 85 QILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKA 144 +Y I + G + G+G G++S A+ + + H E A Sbjct: 26 APIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSDFSIRALDFSKHMN--EIA 82 Query: 145 REEFQEHRVGRWVTVRTQDV 164 + + + + + DV Sbjct: 83 LKNIADANLNDRIQIVQGDV 102 >5BXY-A nrPDB Length = 158 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 95 ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG 154 + + ++ V+ + G+G G + RT G +E +KAR+ +E V Sbjct: 16 MLELADVDETDVLYDLGSGDGRIVIRAARTHGARG--VGIEIDPDLVKKARKNAKEAGVA 73 Query: 155 RWVTVRTQDVCRSGFGVSHV 174 V R D+ + + V Sbjct: 74 DLVEFRQGDLFEADISEATV 93 >3R3H-A nrPDB Length = 242 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 42/117 (35%), Gaps = 6/117 (5%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKA-- 144 + + M++ L V E GT +G + A+ + G + T + ++ + A Sbjct: 44 VAPEQAQFMQMLIRLTRAKKVLELGTFTGYSALAMSLALPDDGQVITCDINEGWTKHAHP 103 Query: 145 -REEFQEHRVGRWVTVRTQDV--CRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKV 198 E ++ + D G H D +F+D + + ALK+ Sbjct: 104 YWREAKQEHKIKLRLGPALDTLHSLLNEGGEHQFDFIFIDA-DKTNYLNYYELALKL 159 >6EC3-A nrPDB Length = 471 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 36/100 (36%), Gaps = 9/100 (9%) Query: 102 RPGS-VVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 PG+ + E G G+ + A+ R + + +E ++ +A + H V +R Sbjct: 73 FPGATRILELGALEGADTLALARQPGTS--ILGLEGREENLRRAEFVMEVHG-ATNVELR 129 Query: 161 TQDVCRSGFGVSHVADAVFL-----DIPSPWEAVGHAWDA 195 DV F DAV + PW + A Sbjct: 130 IADVETLDFATLGRFDAVLCAGLLYHVREPWALLKDAARV 169 >5LOG-A nrPDB Length = 233 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 39/114 (34%), Gaps = 5/114 (4%) Query: 73 PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLH 132 T LP RT + L+++++ L E G +G + + G + Sbjct: 29 LREETSKLPLRTMQIPPEQGQLLSLLVRLIGARKTLEVGVFTGYSTLCTALALPADGRVI 88 Query: 133 TVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRS-----GFGVSHVADAVFLD 181 + ++ AR +Q V + VR D S G D F+D Sbjct: 89 ACDLSEEWVSIARRYWQRAGVADRIEVRLGDAHHSLEALVGSEHRGTFDLAFID 142 >6BQC-A nrPDB Length = 383 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 38/115 (33%), Gaps = 13/115 (11%) Query: 94 LITMMLELRPGSVVCESGTGSGSVSHAII--RTIAPTGHLHTVEFHQQRAEKAREEFQEH 151 +I L+L+PG V + G G G ++H + ++ G + E + E+ Sbjct: 159 MICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCE------ 212 Query: 152 RVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWE---AVGHAWDALKVEGGRF 203 G VT+ QD + + P LK EG Sbjct: 213 --GLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFL 265 >3HM2-A nrPDB Length = 178 Score = 37.9 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 7/157 (4%) Query: 93 ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152 AL L +P + + G GSGS++ +R+ P E ++R E+ Sbjct: 15 ALAISALAPKPHETLWDIGGGSGSIAIEWLRST-PQTTAVCFEISEERRERILSNAINLG 73 Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFL--DIPSPWEAVGHAWDALKVEGGRFCSFSPCI 210 V + V+ Q R+ V D +F+ + +P AW L V GGR + + + Sbjct: 74 VSDRIAVQ-QGAPRAFDDVPDNPDVIFIGGGLTAP-GVFAAAWKRLPV-GGRLVANAVTV 130 Query: 211 EQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPP 247 E ++ AL + +S+ + + +++ P Sbjct: 131 E-SEQMLWALRKQFGGTISSFAISHEHTVGSFITMKP 166 >2PXX-A nrPDB Length = 215 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 51/150 (34%), Gaps = 17/150 (11%) Query: 92 IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH 151 + ELRP + G G+ ++S+ + + ++ +V++ + + Sbjct: 31 SFRALLEPELRPEDRILVLGCGNSALSYELF--LGGFPNVTSVDYSSVVVAAMQACYAHV 88 Query: 152 RVGRWVTVRTQ--DVCRSGFG---VSHVADAVFLDIPSPW-------EAVGHA---WDAL 196 RW T+ + D + F DA+ PW V + Sbjct: 89 PQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRV 148 Query: 197 KVEGGRFCSFSPCIEQVQRTCQALAARGFS 226 V GGRF S + + A A G+S Sbjct: 149 LVPGGRFISMTSAAPHFRTRHYAQAYYGWS 178 >2HNK-A nrPDB Length = 239 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 9/75 (12%), Positives = 31/75 (41%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146 + + + ++ ++ + E GT +G S + G + + ++ AR+ Sbjct: 44 ISPEEGQFLNILTKISGAKRIIEIGTFTGYSSLCFASALPEDGKILCCDVSEEWTNVARK 103 Query: 147 EFQEHRVGRWVTVRT 161 ++E+ + + ++ Sbjct: 104 YWKENGLENKIFLKL 118 >2AS0-A nrPDB Length = 396 Score = 36.7 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 49/138 (35%), Gaps = 6/138 (4%) Query: 51 GRPFGSKVTCGRGGWVYVLHPTPELWTLNLP-HRTQILYSTDIALITMMLELRPGSVVCE 109 G P +V G+ + ++ + +++ +T + + ++PG V + Sbjct: 164 GLPEIERVLLGKEKYRTIIQEGRAKFIVDMRGQKTGFFLDQRENRLALEKWVQPGDRVLD 223 Query: 110 SGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGF 169 T +G AI IA + ++ + E A+E + + V + Sbjct: 224 VFTYTGGF--AIHAAIAGADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSAFEEME 281 Query: 170 GV---SHVADAVFLDIPS 184 + D V LD P+ Sbjct: 282 KLQKKGEKFDIVVLDPPA 299 >4INE-A nrPDB Length = 454 Score = 36.7 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 40/123 (32%), Gaps = 9/123 (7%) Query: 88 YSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147 Y ++ +I + +PG + + G G G + + H+H ++ A E Sbjct: 226 YDENLKIIKRFGDFKPGQTMLDIGVGIGGGARQVADEFGV--HVHGIDLSSNMLAIALER 283 Query: 148 FQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL-----DIPSPWEAVGHAWDALKVEGGR 202 E V D F + D VF IP + + ALK G Sbjct: 284 LHE-EKDSRVKYSITDALVYQF-EDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKV 341 Query: 203 FCS 205 + Sbjct: 342 LIT 344 >4OA5-A nrPDB Length = 227 Score = 36.7 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 2/77 (2%) Query: 107 VCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQD--V 164 + E GT G + + + GH++T+E + A + ++ +TV + Sbjct: 69 IVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALA 128 Query: 165 CRSGFGVSHVADAVFLD 181 + D +F+D Sbjct: 129 QLNTLKEMAPFDMIFID 145 >4DF3-A nrPDB Length = 233 Score = 36.4 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 34/98 (34%), Gaps = 11/98 (11%) Query: 96 TMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGR 155 + L ++ G + G SG+ + + I P G ++ VE A + + R Sbjct: 70 LIELPVKEGDRILYLGIASGTTASHMSDIIGPRGRIYGVE----FAPRVMRDLLTVVRDR 125 Query: 156 WVTVRTQDVCRSGFGVS-----HVADAVFLDIPSPWEA 188 + + F D ++ D+ P +A Sbjct: 126 RNIFPI--LGDARFPEKYRHLVEGVDGLYADVAQPEQA 161 >5WYK-3B nrPDB Length = 327 Score = 36.4 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 38/181 (20%), Positives = 62/181 (34%), Gaps = 24/181 (13%) Query: 71 PTPELWTLNLPHRTQILYSTDIALITMMLE---LRPGSVVCESGTGSGSVSHAIIRTIAP 127 PT + + P R+++ A I L+ + PG V G SG+ + + P Sbjct: 136 PTKVEYRVWNPFRSKL-----AAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGP 190 Query: 128 TGHLHTVEFHQQRAEKAREEFQEHRVGRWV--TVRTQDVCRSGFGVSHVADAVFLDIPSP 185 G ++ VEF + + ++ + R R G + D VF D+ P Sbjct: 191 EGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIG---MVDCVFADVAQP 247 Query: 186 WEA---VGHAWDALKVEGGRFCSFSPCI--------EQVQRTCQALAARGFSELSTLEVL 234 +A ++ LK +GG S R Q L L L + Sbjct: 248 DQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLE 307 Query: 235 P 235 P Sbjct: 308 P 308 >3C3P-A nrPDB Length = 210 Score = 36.4 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 47/130 (36%), Gaps = 6/130 (4%) Query: 57 KVTCGRGGWVYVLHPTPELWTLNLP-----HRTQILYSTDIALITMMLELRPGSVVCESG 111 V G ++ L P + + I+ L+ ++ ++ +V G Sbjct: 5 IVDSRIGAYLDGLLPEADPVVAAMEQIARERNIPIVDRQTGRLLYLLARIKQPQLVVVPG 64 Query: 112 TGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGV 171 G G S R I+ + + ++ + E AR ++ + V ++ D G Sbjct: 65 DGLGCASWWFARAISISSRVVMIDPDRDNVEHARRMLHDNGLIDRVELQVGDPLGIAAGQ 124 Query: 172 SHVADAVFLD 181 + D +F+D Sbjct: 125 RDI-DILFMD 133 >5EVJ-A nrPDB Length = 387 Score = 36.4 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 38/111 (34%), Gaps = 13/111 (11%) Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGR------- 155 G V + G GSG ++ + + G + V+ + E A + + Sbjct: 83 EGLRVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTPAQLEVAISHADAYARDKLGYGKSN 142 Query: 156 --WVTVRTQDVCRSGFGVSH----VADAVFLDIPSPWEAVGHAWDALKVEG 200 ++ + + R+G S +++ V P + A+ L G Sbjct: 143 MTFIQGEIEYLDRAGLEDSSFDLVISNCVINLSPDKARVLSEAYRVLAPGG 193 >3M4X-A nrPDB Length = 456 Score = 36.4 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 29/93 (31%), Gaps = 2/93 (2%) Query: 92 IALIT-MMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE 150 A+I +PG V + G S + + G L T E +RA+ E + Sbjct: 93 SAMIVGTAAAAKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIER 152 Query: 151 HRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183 V + D + +D P Sbjct: 153 WGVSNAIVTNHAPAELVPHFSG-FFDRIVVDAP 184 >5OQL-R nrPDB Length = 313 Score = 36.0 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 34/85 (40%), Gaps = 1/85 (1%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 ++PGS V G SG+ + + PTG ++ VEF R+ + R V Sbjct: 150 MKPGSKVLYLGAASGTSVSHVADIVGPTGAVYAVEFSH-RSGRDLINMATRRTNVIPIVE 208 Query: 161 TQDVCRSGFGVSHVADAVFLDIPSP 185 + + + D +F D+ P Sbjct: 209 DARKPMAYRMLVPMVDVIFADVAQP 233 >3CBG-A nrPDB Length = 232 Score = 36.0 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 33/86 (38%) Query: 76 WTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVE 135 T +LP + + +++ L V E G G + A+ + P G + + Sbjct: 45 ETAHLPGAPMQISPEQAQFLGLLISLTGAKQVLEIGVFRGYSALAMALQLPPDGQIIACD 104 Query: 136 FHQQRAEKAREEFQEHRVGRWVTVRT 161 A++ +Q+ V +++R Sbjct: 105 QDPNATAIAKKYWQKAGVAEKISLRL 130 >4KDR-A nrPDB Length = 223 Score = 35.6 bits (80), Expect = 0.023, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 44/142 (30%), Gaps = 3/142 (2%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAP-TGHLHTVEFHQQRAEKAR 145 + + I G V + G G G ++ ++ R A TG E Q A Sbjct: 46 INPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHAL 105 Query: 146 EEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCS 205 E + + TV +G + +P P V +K G F Sbjct: 106 ESGIQVDYVQE-TVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVF-F 163 Query: 206 FSPCIEQVQRTCQALAARGFSE 227 + V++ + G+ + Sbjct: 164 STLNRNGVKKFIKPAELLGWVD 185 >3VC2-A nrPDB Length = 312 Score = 35.6 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 25/201 (12%), Positives = 57/201 (28%), Gaps = 33/201 (16%) Query: 33 GAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDI 92 +G+ +G P S+ ++ L + ++ Sbjct: 64 DGLYHHHYGIGPVDRAALGDPEHSEYEKKVIAELHRLESAQAEFLMD------------- 110 Query: 93 ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152 + + P + ++G G G R + V +A+ +E R Sbjct: 111 ----HLGQAGPDDTLVDAGCGRGGSMVMAHRRFGS--RVEGVTLSAAQADFGNRRARELR 164 Query: 153 VGRWVTVRTQDVCRSGFGVSHVA------DAVFLDIPSPWEAVGHAWDALKVEGGRFCSF 206 + V R ++ + F V +++D+ + GGR+ + Sbjct: 165 IDDHVRSRVCNMLDTPFDKGAVTASWNNESTMYVDLHD----LFSEHSRFLKVGGRYVTI 220 Query: 207 SPCIE----QVQRTCQALAAR 223 + C Q + + A Sbjct: 221 TGCWNPRYGQPSKWVSQINAH 241 >3R9X-B nrPDB Length = 248 Score = 35.6 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 7/71 (9%) Query: 95 ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG 154 I L + G+ V E G G+G+++ +++ P L+ +E ++ E + Sbjct: 22 IAEELNIEEGNTVVEVGGGTGNLTKVLLQ--HPLKKLYVIELDREM----VENLKSIG-D 74 Query: 155 RWVTVRTQDVC 165 + V +D Sbjct: 75 ERLEVINEDAS 85 >4PON-A nrPDB Length = 200 Score = 35.2 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 22/55 (40%) Query: 96 TMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE 150 + + G +V ++ G+G + + + GH++ + + +E E Sbjct: 19 LLKMAAGEGDIVIDATMGNGHDTQFLAELVGENGHVYAFDIQESAVANTKERLGE 73 >1SQG-A nrPDB Length = 429 Score = 35.2 bits (79), Expect = 0.034, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 43/121 (35%), Gaps = 8/121 (6%) Query: 66 VYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRP--GSVVCESGTGSGSVSHAIIR 123 V + P P + D + M L P G + + G + I+ Sbjct: 209 VRLETPAPVHALPGFEDGWVTV--QDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHIL- 265 Query: 124 TIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQD-VCRSGFGVSHVADAVFLDI 182 +AP + V+ +QR + + + R+G TV+ D S + D + LD Sbjct: 266 EVAPEAQVVAVDIDEQRLSRVYDNLK--RLGMKATVKQGDGRYPSQWCGEQQFDRILLDA 323 Query: 183 P 183 P Sbjct: 324 P 324 >1QAM-A nrPDB Length = 244 Score = 35.2 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 39/106 (36%), Gaps = 8/106 (7%) Query: 79 NLPHRTQILYST-DIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFH 137 N+ H + S +I I + L + E G+G G + + + + +E Sbjct: 5 NIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLEL---VQRCNFVTAIEID 61 Query: 138 QQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183 + + + +H V +D+ + F + +F +IP Sbjct: 62 HKLCKTTENKLVDH---DNFQVLNKDILQFKFPKNQSY-KIFGNIP 103 >3EVZ-A nrPDB Length = 230 Score = 34.4 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 2/77 (2%) Query: 75 LWTLNLPHRTQ-ILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT 133 L+ L++ + + ++ + I + LR G V E GTG ++ + + Sbjct: 26 LFGLDIEYHPKGLVTTPISRYIFLKTFLRGGEVALEIGTGHTAMMALMAEKFFNC-KVTA 84 Query: 134 VEFHQQRAEKAREEFQE 150 E ++ E AR + Sbjct: 85 TEVDEEFFEYARRNIER 101 >6IFX-A nrPDB Length = 287 Score = 34.4 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 31/204 (15%), Positives = 73/204 (35%), Gaps = 26/204 (12%) Query: 73 PELWTLNLPHRTQILYSTDIAL---ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTG 129 + + + + D + I E+ + V E G G G+++ + + Sbjct: 15 LKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAK---RAK 71 Query: 130 HLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGF-----GVSHVADAVFLDIPS 184 + E Q+ ++ + VTV QDV ++ D + + Sbjct: 72 KVVAFEIDQRLLPILKDTLSPY---ENVTVIHQDVLKADVKSVIEEQFQDCDEIMVVANL 128 Query: 185 PWEA-----VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALA--ARGFSELSTLEVLPQV 237 P+ + + L ++G E++ T ++L+ + ++E T+ ++P Sbjct: 129 PYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMANTKRSLSIAVQFYTEAKTVMIVP-- 186 Query: 238 YNVRTVSLPPPDLGTGTDGPAGSD 261 +TV +P P++ + D Sbjct: 187 ---KTVFVPQPNVDSAVIRLILRD 207 >5YLN-A nrPDB Length = 356 Score = 34.4 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 59/179 (32%), Gaps = 20/179 (11%) Query: 10 IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69 K+GD ++S G + G+ H D G FG + + ++ V Sbjct: 80 FKKGDKVLIS--------CVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQAEYLRVP 131 Query: 70 HP------TPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIR 123 H TPE + + T + + ++ PG V G+G ++ + Sbjct: 132 HADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAIIGSGPVGLAALLTA 191 Query: 124 TIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDI 182 L V+ R E A G V + D ++ + + D +D+ Sbjct: 192 QFYSPAKLIMVDLDDNRLETALS------FGATHKVNSSDPEKAIKEIYDLTDGRGVDV 244 >3NJR-A nrPDB Length = 204 Score = 34.0 bits (76), Expect = 0.068, Method: Composition-based stats. Identities = 27/109 (24%), Positives = 37/109 (33%), Gaps = 14/109 (12%) Query: 80 LPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQ 139 H QI S AL L R G ++ + G GSGSVS G T+E Sbjct: 32 FAHDGQITKSPMRALTLAALAPRRGELLWDIGGGSGSVSVEWCLA---GGRAITIEPRAD 88 Query: 140 RAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188 R E ++ + + + V A A D+P P Sbjct: 89 RIENIQKNIDTYGLSPRMR-----------AVQGTAPAALADLPLPEAV 126 >2VS1-A nrPDB Length = 425 Score = 34.0 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 24/149 (16%), Positives = 45/149 (30%), Gaps = 13/149 (8%) Query: 63 GGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAII 122 G + ++ Q + L+ + EL G + + +G G+ + Sbjct: 250 GKEFIRERLDDVDYLIHPNSFFQTNSYQAVNLVRKVSELVEGEKILDMYSGVGTFGIYLA 309 Query: 123 -RTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG-RWVTVRTQDVCRSGFGVSHVADAVFL 180 R G + ++ E AR + + V + ++V GF D V + Sbjct: 310 KRGFNVKG----FDSNEFAIEMARRNVEINNVDAEFEVASDREVSVKGF------DTVIV 359 Query: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPC 209 D P L E + C Sbjct: 360 DPPRAGLH-PRLVKRLNREKPGVIVYVSC 387 >2B3T-A nrPDB Length = 276 Score = 34.0 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 27/190 (14%), Positives = 56/190 (29%), Gaps = 16/190 (8%) Query: 16 AILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPEL 75 +L G + G T + L R G + G + P Sbjct: 26 ILLEHVTGRGRTFILAFGETQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVS 85 Query: 76 WTLNLPHRTQILYSTDIALITMMLELRPGS--VVCESGTGSGSVSHAIIRTIAPTGHLHT 133 +P L+ L P + + GTG+G+++ A+ P + Sbjct: 86 PATLIPR------PDTECLVEQALARLPEQPCRILDLGTGTGAIALALASE-RPDCEIIA 138 Query: 134 VEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAW 193 V+ A+ Q + ++ + +S + + + + +P + Sbjct: 139 VDRMPDAVSLAQRNAQH------LAIKNIHILQSDWFSALAGQQFAMIVSNP-PYIDEQD 191 Query: 194 DALKVEGGRF 203 L+ RF Sbjct: 192 PHLQQGDVRF 201 >3D2L-A nrPDB Length = 243 Score = 33.7 bits (75), Expect = 0.097, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 55/156 (35%), Gaps = 29/156 (18%) Query: 88 YSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147 Y +A + +E PG + + G G+G+ + + TG + E + EKA E Sbjct: 20 YPEWVAWVLEQVE--PGKRIADIGCGTGTATLLLADHYEVTGVDLSEEMLEIAQEKAMET 77 Query: 148 FQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFS 207 R V QD+ L++P P +A+ D+L + Sbjct: 78 ------NRHVDFWVQDMRE-------------LELPEPVDAITILCDSLN--------YL 110 Query: 208 PCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTV 243 V++T + A L + Y + T+ Sbjct: 111 QTEADVKQTFDSAARLLTDGGKLLFDVHSPYKMETL 146 >6IFV-A nrPDB Length = 215 Score = 33.3 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 50/152 (32%), Gaps = 21/152 (13%) Query: 73 PELWTLNLPHRTQILYSTDIAL---ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTG 129 + + + + D + I E+ + V E G G G+++ + + Sbjct: 15 LKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAK---RAK 71 Query: 130 HLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189 + E Q+ ++ + VTV QDV ++ V V + F D Sbjct: 72 KVVAFEIDQRLLPILKDTLSPY---ENVTVIHQDVLKA--DVKSVIEEQFQD-------- 118 Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALA 221 + + V + +P I ++ L Sbjct: 119 --CDEIMVVANLPYYVTTPIIMKLLEEHLPLK 148 >3R0Q-C nrPDB Length = 376 Score = 33.3 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 26/71 (36%), Gaps = 3/71 (4%) Query: 102 RPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRT 161 G V + GTGSG AI A ++ VE + A+ AR + + + V V Sbjct: 62 FEGKTVLDVGTGSG--ILAIWSAQAGARKVYAVEATK-MADHARALVKANNLDHIVEVIE 118 Query: 162 QDVCRSGFGVS 172 V Sbjct: 119 GSVEDISLPEK 129 >1ZQ9-A nrPDB Length = 285 Score = 33.3 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 34/95 (35%), Gaps = 6/95 (6%) Query: 89 STDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEF 148 I I LRP VV E G G+G+++ ++ + E + + + Sbjct: 14 PLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLE---KAKKVVACELDPRLVAELHKRV 70 Query: 149 QEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183 Q V + V DV ++ D ++P Sbjct: 71 QGTPVASKLQVLVGDVLKTDLP---FFDTCVANLP 102 >1EIZ-A nrPDB Length = 180 Score = 32.5 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 35/120 (29%), Gaps = 22/120 (18%) Query: 102 RPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT-------------VEFHQQRAEKAREEF 148 +PG V + G G S ++ I G + R E + Sbjct: 21 KPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKAL 80 Query: 149 QEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDA---LKVEGGRFCS 205 E V V D+ +++ +DIP V A + + GG F Sbjct: 81 LERVGDSKVQVVMSDMAP------NMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVV 134 >2NNW-B nrPDB Length = 234 Score = 32.5 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 58/160 (36%), Gaps = 15/160 (9%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 ++PG V G SG+ + + + G ++ +EF + + +E R + Sbjct: 78 IKPGKSVLYLGIASGTTASHVSDIVGWEGKIYGIEFSPRVLRELVPIVEER---RNIIPI 134 Query: 161 TQDVCRSGFGVSHVA--DAVFLDIPSPWEA---VGHAWDALKVEG-------GRFCSFSP 208 D + + V D +F D+ P +A + +A LK G R + Sbjct: 135 LGDATKPEEYRALVTKVDVIFEDVAQPTQAKILIDNAKAYLKRGGYGMIAVKSRSIDVTK 194 Query: 209 CIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248 EQV + + + F + L + P + + P Sbjct: 195 EPEQVFKEVERELSEYFEVIERLNLEPYEKDHALFVVRKP 234 >4FZV-A nrPDB Length = 359 Score = 32.5 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 8/103 (7%) Query: 88 YSTDIALI--TMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAR 145 Y D A + + L L+PG +V + G + A+++T +L + R + + Sbjct: 131 YLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQT-GCCRNLAANDLSPSRIARLQ 189 Query: 146 EEF-----QEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183 + +E R G V V + D + G D V +D+P Sbjct: 190 KILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVP 232 >2YXD-A nrPDB Length = 183 Score = 32.5 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 13/100 (13%), Positives = 32/100 (32%), Gaps = 6/100 (6%) Query: 81 PHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQR 140 I A+ L L VV + G GSG ++ I + ++ +++ Sbjct: 13 REGVPITKEEIRAVSIGKLNLNKDDVVVDVGCGSGGMTVEIAKRCK---FVYAIDYLDGA 69 Query: 141 AEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180 E ++ + + ++ + + F+ Sbjct: 70 IEVTKQNLAKFNIKNCQIIKGR---AEDVLDKLEFNKAFI 106 >4KDC-A nrPDB Length = 246 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 36/118 (30%), Gaps = 2/118 (1%) Query: 87 LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAP-TGHLHTVEFHQQRAEKAR 145 + + I G V + G G G ++ ++ R A TG E Q A Sbjct: 46 INPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHAL 105 Query: 146 EEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRF 203 E + + TV +G + +P P V +K G F Sbjct: 106 ESGIQVDYVQE-TVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVF 162 >5WWT-A nrPDB Length = 477 Score = 31.3 bits (69), Expect = 0.44, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 35/103 (33%), Gaps = 11/103 (10%) Query: 92 IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE---- 147 AL++ +L +PG + + G + I + G + ++ + EK ++ Sbjct: 223 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLL 282 Query: 148 ----FQEHRVGRWVTVR---TQDVCRSGFGVSHVADAVFLDIP 183 + V+ +D + D + LD P Sbjct: 283 GLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325 >3DMF-A nrPDB Length = 381 Score = 31.3 bits (69), Expect = 0.45, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 48/136 (35%), Gaps = 13/136 (9%) Query: 104 GSVVCESGTGSGSVSHAIIR----TIAPTGHLHTVEFHQQRAEKA--REEFQEHRVGRWV 157 G V + G G G+++ + R + L +V Q+ E + + V + Sbjct: 234 GRQVLDLGAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEAL 293 Query: 158 TVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTC 217 T + HV AV LD+ V A L+ G F +P ++ Sbjct: 294 TEEARFDIIVTNPPFHVGGAVILDVAQ--AFVNVAAARLRPGGVFFLVSNPFLK-----Y 346 Query: 218 QALAARGFSELSTLEV 233 + L F TL+V Sbjct: 347 EPLLEEKFGAFQTLKV 362 >4F86-A nrPDB Length = 320 Score = 31.3 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 26/200 (13%), Positives = 57/200 (28%), Gaps = 31/200 (15%) Query: 33 GAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDI 92 +G+ +G P ++ L + L+ Sbjct: 72 DGLYHHHYGIGAVDHAALGDPGDGGYEARLIAELHRLESAQAEFLLD------------- 118 Query: 93 ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152 + + PG + ++G G G + + V +AE +E Sbjct: 119 ----HLGPVGPGDTLVDAGCGRGGSMVMAHQRFGCK--VEGVTLSAAQAEFGNRRARELG 172 Query: 153 VGRWVTVRTQDVCRSGFGVSHVA------DAVFLDIPSPWEAVGHAWDALKVEG---GRF 203 + V R ++ + F VA ++++D+ + L+V G Sbjct: 173 IDDHVRSRVCNMLDTPFEKGTVAASWNNESSMYVDL---HDVFAEHSRFLRVGGRYVTVT 229 Query: 204 CSFSPCIEQVQRTCQALAAR 223 ++P Q + + A Sbjct: 230 GCWNPRYGQPSKWVSQINAH 249 >4FS8-A nrPDB Length = 383 Score = 31.0 bits (68), Expect = 0.55, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 22/49 (44%) Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH 151 G+ V + G G+G + + + G + V+ + E AR+ + H Sbjct: 83 EGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQLEVARKYVEYH 131 >5WP5-A nrPDB Length = 491 Score = 31.0 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 47/153 (30%), Gaps = 7/153 (4%) Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWV--TVR 160 G V E G G G + + + G + ++F + +K ++ +++ V Sbjct: 53 EGKSVLELGAGIGRFTGELAQ---KAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVT 109 Query: 161 TQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALK--VEGGRFCSFSPCIEQVQRTCQ 218 + D+ + + L S E A + GG C Q + + Sbjct: 110 SPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKR 169 Query: 219 ALAARGFSELSTLEVLPQVYNVRTVSLPPPDLG 251 + E + Q R S +L Sbjct: 170 KSNPTHYREPRFYTKVFQECQTRDASGNSFELS 202 >5FUB-A nrPDB Length = 337 Score = 31.0 bits (68), Expect = 0.61, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 25/69 (36%), Gaps = 2/69 (2%) Query: 104 GSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQD 163 VV + G G+G +S P G ++ VE AE E +++ VTV + Sbjct: 45 EKVVLDLGCGTGVISLFCALLAKPAG-VYAVEA-SSMAEHTEELVKQNGCDGVVTVFQER 102 Query: 164 VCRSGFGVS 172 Sbjct: 103 AENLTLPTK 111 >3CJR-A nrPDB Length = 254 Score = 30.6 bits (67), Expect = 0.88, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 46/129 (35%), Gaps = 6/129 (4%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 LRPG V + GTGSG ++ A + G V+ +A + + V Sbjct: 118 LRPGDKVLDLGTGSGVLAIA-AEKLG--GKALGVDIDPMVLPQAEANAKRNGVRPRFLEG 174 Query: 161 TQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQAL 220 + + + ++ ++ A+ + V GGR ++ +A+ Sbjct: 175 SLEAALPFGPFDLLVANLYAEL---HAALAPRYREALVPGGRALLTGILKDRAPLVREAM 231 Query: 221 AARGFSELS 229 A GF L Sbjct: 232 AGAGFRPLE 240 >4DZR-A nrPDB Length = 215 Score = 30.2 bits (66), Expect = 0.96, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 2/54 (3%) Query: 104 GSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-VGRW 156 G+ V + GTGSG ++ +I P + V+ AR + V W Sbjct: 31 GTRVIDVGTGSGCIAVSIALAC-PGVSVTAVDLSMDALAVARRNAERFGAVVDW 83 >3E23-A nrPDB Length = 211 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 41/143 (28%), Gaps = 23/143 (16%) Query: 75 LWTLNLPHRTQILY----STDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGH 130 TL Y L + EL G+ + E G G+G + G Sbjct: 11 DDTLRFYRGNATAYAERQPRSATLTKFLGELPAGAKILELGCGAG----YQAEAMLAAG- 65 Query: 131 LHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAV-----FLDIPSP 185 V+ E A E + + Q DAV L +P Sbjct: 66 -FDVDATDGSPELAAEASRRLGRPVRTMLFHQ------LDAIDAYDAVWAHACLLHVPRD 118 Query: 186 W--EAVGHAWDALKVEGGRFCSF 206 + + W ALK G + S+ Sbjct: 119 ELADVLKLIWRALKPGGLFYASY 141 >6H1E-A nrPDB Length = 208 Score = 29.8 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 9/21 (42%), Positives = 11/21 (52%) Query: 108 CESGTGSGSVSHAIIRTIAPT 128 E G+GSG VS + I P Sbjct: 44 LEVGSGSGVVSAFLASMIGPQ 64 >4JJI-A nrPDB Length = 378 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 28/78 (35%), Gaps = 4/78 (5%) Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160 + PGS V G G+ ++ A A + ++ ++ E A ++ V +V + Sbjct: 191 VEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETA----KKFGVNEFVNPK 246 Query: 161 TQDVCRSGFGVSHVADAV 178 D V V Sbjct: 247 DHDKPIQEVIVDLTDGGV 264 >1TPY-A nrPDB Length = 287 Score = 29.0 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 35/103 (33%), Gaps = 9/103 (8%) Query: 64 GWVYVLHPTPELWTLNLPHRTQILYSTDIALI---TMMLELRPGSVVCESGTGSGS-VSH 119 + L PT + L IA I L L+PG + + G G G+ + Sbjct: 22 FFRLFLDPTQTYSCAHFEREDMTLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRR 81 Query: 120 AII-RTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRT 161 AI + G + + +A ++ F E R V Sbjct: 82 AIAQYDVNVVGLTLS----KNQAAHVQKSFDEMDTPRDRRVLL 120 >1VQ1-A nrPDB Length = 294 Score = 29.0 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 105 SVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDV 164 V + GTGSG++ ++ + + + + E AR+ + H V VR + Sbjct: 135 KTVADIGTGSGAIGVSVAKF--SDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGEF 192 >3W53-A nrPDB Length = 506 Score = 28.7 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 36/98 (36%), Gaps = 3/98 (3%) Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248 V W+ + ++ S+ E + Q L E LE++ Q + V+ Sbjct: 280 VDALWNRMYLDPVLRGSYP---EDLLEDVQGLGLAEVIEAGDLEIISQPIDFLGVNHYHD 336 Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286 D +G PAG + +P + Y+TF + Sbjct: 337 DNVSGHPLPAGQPQPVVPTDSPKSSPFVGSEYVTFPAR 374 >1F8F-A nrPDB Length = 371 Score = 28.7 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 21/55 (38%) Query: 92 IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146 L++ P S G G+ +S + + + V+ + R E A++ Sbjct: 179 AGACINALKVTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQ 233 >5TNX-A nrPDB Length = 383 Score = 28.3 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 28/86 (32%), Gaps = 11/86 (12%) Query: 92 IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE----- 146 + L +R GS G G+ +S + IA + V+ R A E Sbjct: 190 AGAVINSLAVRTGSSFASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATH 249 Query: 147 --EFQEHRVGRWVTVRTQDVCRSGFG 170 +E V + +++ G Sbjct: 250 AINSKEVDVVDAI----REITGGGVD 271 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.120 0.293 Lambda K H 0.267 0.0367 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,786,733 Number of Sequences: 36641 Number of extensions: 363166 Number of successful extensions: 1179 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 79 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1039 Number of HSP's gapped (non-prelim): 131 length of query: 289 length of database: 10,336,785 effective HSP length: 96 effective length of query: 193 effective length of database: 6,819,249 effective search space: 1316115057 effective search space used: 1316115057 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.1 bits)