BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= Q96FX7
         (289 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

5CCX-A nrPDB                                                          591   e-169
5EQJ-B nrPDB                                                          186   7e-48
1O54-A nrPDB                                                          119   2e-27
3LGA-A nrPDB                                                           96   2e-20
1YB2-A nrPDB                                                           82   3e-16
1I9G-A nrPDB                                                           79   2e-15
2YVL-A nrPDB                                                           67   7e-12
2PWY-A nrPDB                                                           53   1e-07
2B25-A nrPDB                                                           49   2e-06
5X7F-A nrPDB                                                           39   0.003
4O29-A nrPDB                                                           38   0.006
3TFW-A nrPDB                                                           35   0.042
5N5D-A nrPDB                                                           32   0.23 
5OQL-R nrPDB                                                           32   0.32 
3TMA-A nrPDB                                                           31   0.68 
2YXE-A nrPDB                                                           30   1.0  
1JG3-A nrPDB                                                           30   1.7  
4F4F-A nrPDB                                                           28   3.2  
3LBF-A nrPDB                                                           28   3.3  
3CJR-A nrPDB                                                           28   3.9  
1DL5-A nrPDB                                                           28   5.1  
1E6V-A nrPDB                                                           27   7.8  

>5CCX-A nrPDB
          Length = 289

 Score =  591 bits (1524), Expect = e-169,   Method: Compositional matrix adjust.
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60
           MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC
Sbjct: 1   MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60

Query: 61  GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120
           GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA
Sbjct: 61  GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120

Query: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180
           IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL
Sbjct: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180

Query: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240
           DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV
Sbjct: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240

Query: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289
           RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG
Sbjct: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289


>5EQJ-B nrPDB
          Length = 383

 Score =  186 bits (473), Expect = 7e-48,   Method: Compositional matrix adjust.
 Identities = 105/263 (39%), Positives = 149/263 (56%), Gaps = 28/263 (10%)

Query: 3   FVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVT--- 59
           F  Y++LIKEGD  ++ +    +  VR+       TR+G   H  D+IG+P+GS++    
Sbjct: 6   FSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRYGSFPHK-DIIGKPYGSQIAIRT 64

Query: 60  --CGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSV 117
               +  +V+VL PTPELWTL+LPHRTQI+Y+ D + I   L   P S V E+GTGSGS 
Sbjct: 65  KGSNKFAFVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSF 124

Query: 118 SHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH-RVGRWVTVRTQDVCRSGF------- 169
           SHA  R++   GHL + EFH  R E+A EEF+EH  +   VT+  +DVC+ GF       
Sbjct: 125 SHAFARSV---GHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRDVCQGGFLIKKGDT 181

Query: 170 ----------GVSHVADAVFLDIPSPWEAVGHAWDALKV-EGGRFCSFSPCIEQVQRTCQ 218
                       S  A+ VFLD+P+PW+A+ H    + V E    C FSPCIEQV +T  
Sbjct: 182 TSYEFGNNETAASLNANVVFLDLPAPWDAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLD 241

Query: 219 ALAARGFSELSTLEVLPQVYNVR 241
            L   G++++  +E+  + Y  R
Sbjct: 242 VLEKYGWTDVEMVEIQGRQYESR 264


>1O54-A nrPDB
          Length = 277

 Score =  119 bits (297), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 77/278 (27%), Positives = 129/278 (46%), Gaps = 27/278 (9%)

Query: 10  IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69
           +K GD  +LS    +   V +++  +  T  G++  + ++  +  G  +    G   Y+L
Sbjct: 20  LKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGIIDLN-EVFEKGPGEIIRTSAGKKGYIL 78

Query: 70  HPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTG 129
            P+     +N+  RTQI+Y  D + I MML+++ G  + ++G GSG++   + R +  +G
Sbjct: 79  IPSLIDEIMNMKRRTQIVYPKDSSFIAMMLDVKEGDRIIDTGVGSGAMCAVLARAVGSSG 138

Query: 130 HLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189
            +   E  ++ A+ A     +  +   VT++ +D+   GF    V DA+FLD+P PW  +
Sbjct: 139 KVFAYEKREEFAKLAESNLTKWGLIERVTIKVRDIS-EGFDEKDV-DALFLDVPDPWNYI 196

Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPD 249
              W+ALK  GGRF +  P   QVQ T + L    F  +   E L + Y       P P+
Sbjct: 197 DKCWEALK-GGGRFATVCPTTNQVQETLKKLQELPFIRIEVWESLFRPYK------PVPE 249

Query: 250 LGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKT 287
                               P+   V HT Y+ FATK 
Sbjct: 250 -----------------RLRPVDRMVAHTAYMIFATKV 270


>3LGA-A nrPDB
          Length = 253

 Score = 95.9 bits (237), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 77/278 (27%), Positives = 122/278 (43%), Gaps = 26/278 (9%)

Query: 9   LIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYV 68
           +I+EGD  +L    G    + V +     T  G+L+   ++IGR FG  +   +G    +
Sbjct: 1   MIREGDKVVLVDPRGKRYLITVSK-RDFHTDLGILKLE-EIIGRNFGEAIKSHKGHEFKI 58

Query: 69  LHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128
           L P    +   +    QI++  D ALI     + PG  + E+G GSG+++  +   + P 
Sbjct: 59  LRPRIVDYLDKMKRGPQIVHPKDAALIVAYAGISPGDFIVEAGVGSGALTLFLANIVGPE 118

Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188
           G + + E  +  A+ A E  +       VT++ +D+   G    +V D V LD+P P   
Sbjct: 119 GRVVSYEIREDFAKLAWENIKWAGFDDRVTIKLKDIY-EGIEEENV-DHVILDLPQPERV 176

Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248
           V HA  ALK  GG F +++PC  QV R  + L      E     + P+  NV        
Sbjct: 177 VEHAAKALK-PGGFFVAYTPCSNQVMRLHEKL-----REFKDYFMKPRTINVLVF----- 225

Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286
                 D     +        P   A+ HTGY+TFA +
Sbjct: 226 ------DQEVKKECM-----RPRTTALVHTGYITFARR 252


>1YB2-A nrPDB
          Length = 275

 Score = 82.0 bits (201), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 63/219 (28%), Positives = 94/219 (42%), Gaps = 28/219 (12%)

Query: 72  TPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHL 131
           +P  +   +   TQI+   D + I M   LRPG  + E G GSG++S  I+  +   G L
Sbjct: 79  SPMYFGRVIRRNTQIISEIDASYIIMRCGLRPGMDILEVGVGSGNMSSYILYALNGKGTL 138

Query: 132 HTVEFHQQRAEKAREEFQE-HRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVG 190
             VE  +   +KA +   E + +G    VRT     + F    + DAV  DIP PW  V 
Sbjct: 139 TVVERDEDNLKKAMDNLSEFYDIG---NVRTSRSDIADFISDQMYDAVIADIPDPWNHVQ 195

Query: 191 HAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPDL 250
                +K  G     + P  +Q ++T  +L+A G   L T+E++ +   VR         
Sbjct: 196 KIASMMK-PGSVATFYLPNFDQSEKTVLSLSASGMHHLETVELMKRRILVR--------- 245

Query: 251 GTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289
             G   PA  D +             HT ++TFA K  G
Sbjct: 246 -EGATRPASDDLT-------------HTAFITFAIKKSG 270


>1I9G-A nrPDB
          Length = 280

 Score = 79.0 bits (193), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 66/239 (27%), Positives = 108/239 (45%), Gaps = 8/239 (3%)

Query: 13  GDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPT 72
           G+   L+   G    + +  GA+  T  G + H   +IG   GS V    G    VL P 
Sbjct: 10  GERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDA-VIGLEQGSVVKSSNGALFLVLRPL 68

Query: 73  PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLH 132
              + +++P   Q++Y  D A I    ++ PG+ V E+G GSG+++ +++R + P G + 
Sbjct: 69  LVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVI 128

Query: 133 TVEFHQQRAEKAREEFQ---EHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189
           + E     AE AR             W  V   D+  S      V D   LD+ +PWE +
Sbjct: 129 SYEQRADHAEHARRNVSGCYGQPPDNWRLV-VSDLADSELPDGSV-DRAVLDMLAPWEVL 186

Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARG-FSELSTLEVLPQVYNVRTVSLPP 247
             A   L V GG    +   + Q+ R  +AL A+  ++E    E L + +NV  +++ P
Sbjct: 187 -DAVSRLLVAGGVLMVYVATVTQLSRIVEALRAKQCWTEPRAWETLQRGWNVVGLAVRP 244


>2YVL-A nrPDB
          Length = 248

 Score = 67.4 bits (163), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 72/280 (25%), Positives = 122/280 (43%), Gaps = 41/280 (14%)

Query: 10  IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69
            KEG+  ++  G    +   + + + +  +  VL+   ++IG+P G K+    G  VY  
Sbjct: 4   FKEGEYVLIRFGEKKFLRKLLPKQSLS-VKKSVLKFD-EVIGKPEGVKIN---GFEVY-- 56

Query: 70  HPT-PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128
            PT  E+  L    +TQI+Y  D   I + L L     V E GTGSG++  A++  +A  
Sbjct: 57  RPTLEEIILLGFERKTQIIYPKDSFYIALKLNLNKEKRVLEFGTGSGALL-AVLSEVA-- 113

Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGF--GVSHVADAVFLDIPSPW 186
           G + T E  ++  + A++  ++  +G+ V     D   +    G+ H   A F+D+  PW
Sbjct: 114 GEVWTFEAVEEFYKTAQKNLKKFNLGKNVKFFNVDFKDAEVPEGIFH---AAFVDVREPW 170

Query: 187 EAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLP 246
             +     +L +EG       P   QV +  +++    F  L  +E+L + Y  +T+S  
Sbjct: 171 HYLEKVHKSL-MEGAPVGFLLPTANQVIKLLESI-ENYFGNLEVVEILHRHY--KTIS-- 224

Query: 247 PPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286
                             FR   P  + V HT YL F  K
Sbjct: 225 ----------------ERFR---PEDQMVAHTAYLVFGRK 245


>2PWY-A nrPDB
          Length = 258

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 48/175 (27%), Positives = 79/175 (45%), Gaps = 10/175 (5%)

Query: 71  PTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGH 130
           PT E + L++       Y  D + +  +L+L PG  V E+GTGSG ++  + R +   G 
Sbjct: 64  PTLEEYLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGL 123

Query: 131 LHTVE---FHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWE 187
           + + E    H  +AE+    F +    R+   + ++            D V LD+  PW+
Sbjct: 124 VESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELE----EAAYDGVALDLMEPWK 179

Query: 188 AVGHAWDALKVEGGRF-CSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVR 241
            +  A  AL ++  RF  ++ P I QV    +A  A  F     LEV  + + VR
Sbjct: 180 VLEKA--ALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVR 232


>2B25-A nrPDB
          Length = 336

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 19/198 (9%)

Query: 49  LIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVC 108
           ++G+  G  +    G    +  P  E + + +   T I +  DI +I  M+++ PG  V 
Sbjct: 51  IVGKFPGQILRSSFGKQYMLRRPALEDYVVLMKRGTAITFPKDINMILSMMDINPGDTVL 110

Query: 109 ESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-------VGRW---VT 158
           E+G+GSG +S  + + +   G + + E  +   + A++ ++  R       V  W   V 
Sbjct: 111 EAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLSHVEEWPDNVD 170

Query: 159 VRTQDVCRSGFGVSHVA-DAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQV---- 213
              +D+  +   +  +  DAV LD+ +P   +   +  LK  GG    +   I QV    
Sbjct: 171 FIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLK-HGGVCAVYVVNITQVIELL 229

Query: 214 --QRTCQ-ALAARGFSEL 228
              RTC+ AL+    SE+
Sbjct: 230 DGIRTCELALSCEKISEV 247


>5X7F-A nrPDB
          Length = 235

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 6/93 (6%)

Query: 93  ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152
           AL+ ++ +L  G  V E GTG+G     ++  +   G L T++   +    AR+ F E  
Sbjct: 68  ALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDIEPEHLRLARQAFAEAG 127

Query: 153 VG----RWVTVRTQDVCRSGFGVSHVADAVFLD 181
           +G    R ++ R Q+V       S+  D VF+D
Sbjct: 128 IGPSRTRLISGRAQEVLTRLADASY--DLVFID 158


>4O29-A nrPDB
          Length = 208

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 10/80 (12%)

Query: 77  TLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEF 136
           T++ PH         +A++  ++E RPG  + E GTGSG  +      I   G ++T+E 
Sbjct: 57  TISAPHM--------VAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYTIEI 108

Query: 137 HQQRAEKAREEFQEHRVGRW 156
            ++ A  A +  +  R+G W
Sbjct: 109 VKELAVFAAQNLE--RLGYW 126


>3TFW-A nrPDB
          Length = 248

 Score = 35.0 bits (79), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153
            + +++ L     + E GT  G  +  + R +   G L T+E     A+ ARE  Q   V
Sbjct: 54  FLALLVRLTQAKRILEIGTLGGYSTIWMARELPADGQLLTLEADAHHAQVARENLQLAGV 113

Query: 154 GRWVTVRTQDVCRS--GFGVSHVADAVFLDIPSP 185
            + VT+R     +S    G     D +F+D   P
Sbjct: 114 DQRVTLREGPALQSLESLGECPAFDLIFIDADKP 147


>5N5D-A nrPDB
          Length = 226

 Score = 32.3 bits (72), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 29/64 (45%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153
           L+ ++  LR    + E GT  G  S  + R + P G L T+E+ +  AE A     E  V
Sbjct: 52  LLHLLARLRQARRILEIGTFGGYSSIWLARALPPDGRLVTIEWERSFAESAASRLAEAGV 111

Query: 154 GRWV 157
              V
Sbjct: 112 AHLV 115


>5OQL-R nrPDB
          Length = 313

 Score = 32.0 bits (71), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 7/129 (5%)

Query: 99  LELRPGSVVCESGTGSG-SVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWV 157
           + ++PGS V   G  SG SVSH +   + PTG ++ VEF   R+ +        R     
Sbjct: 148 IYMKPGSKVLYLGAASGTSVSH-VADIVGPTGAVYAVEF-SHRSGRDLINMATRRTNVIP 205

Query: 158 TVRTQDVCRSGFGVSHVADAVFLDIPSPWEA--VG-HAWDALKVEGGRFCSF-SPCIEQV 213
            V       +   +  + D +F D+  P +A  VG +A   LK  GG   S  + CI+  
Sbjct: 206 IVEDARKPMAYRMLVPMVDVIFADVAQPDQARIVGINARLFLKQGGGLLISIKASCIDST 265

Query: 214 QRTCQALAA 222
               Q  A+
Sbjct: 266 APPEQVFAS 274


>3TMA-A nrPDB
          Length = 354

 Score = 30.8 bits (68), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 28/52 (53%)

Query: 95  ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146
           +  + + RPG  V +  TGSG+++     T+ PT  ++  +  ++R   ARE
Sbjct: 195 LLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLARE 246


>2YXE-A nrPDB
          Length = 215

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 28/53 (52%)

Query: 92  IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKA 144
           + ++  +L+L+PG  V E GTG G  +      +   G + ++E   + AEKA
Sbjct: 66  VGMMCELLDLKPGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKA 118


>1JG3-A nrPDB
          Length = 235

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 10/79 (12%)

Query: 71  PTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGH 130
           P P   T++ PH         +A++  +  L+PG  + E GTGSG  + A+I  I  T  
Sbjct: 67  PIPAGQTVSAPHM--------VAIMLEIANLKPGMNILEVGTGSGW-NAALISEIVKT-D 116

Query: 131 LHTVEFHQQRAEKAREEFQ 149
           ++T+E   +  E A+   +
Sbjct: 117 VYTIERIPELVEFAKRNLE 135


>4F4F-A nrPDB
          Length = 468

 Score = 28.5 bits (62), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 18/95 (18%)

Query: 195 ALKVEGGRFCSFSPCIEQVQ------RTCQALAARGFSELSTLEVLPQV--YNVRTVSLP 246
           AL +EG    +F  C   V+        C AL+  G + ++   ++PQV  Y    +SL 
Sbjct: 192 ALSIEG----NFDDCQNLVKGMFNDLEFCDALSLSGVNSINWARIMPQVVYYFTAALSLG 247

Query: 247 PPDLGTGTDGPAGSDTSPF------RSGTPMKEAV 275
            PD       P G+    F      R G P+++ +
Sbjct: 248 APDRAVSFTVPTGNFGDIFAGYVAKRMGLPIEQLI 282


>3LBF-A nrPDB
          Length = 210

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 30/62 (48%)

Query: 92  IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH 151
           +A +T +LEL P S V E GTGSG  +  +   +     +  ++  Q +A +  +    H
Sbjct: 66  VARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLH 125

Query: 152 RV 153
            V
Sbjct: 126 NV 127


>3CJR-A nrPDB
          Length = 254

 Score = 28.5 bits (62), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 89  STDIALITMMLELRPGSVVCESGTGSGSVSHA 120
           +T +AL  +   LRPG  V + GTGSG ++ A
Sbjct: 106 TTRLALKALARHLRPGDKVLDLGTGSGVLAIA 137


>1DL5-A nrPDB
          Length = 317

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 13/120 (10%)

Query: 89  STDIALITMMLE---LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAR 145
           S+  +L+ + +E   L  G  V E G G+G  +  + R +   G + +VE+ ++  E A+
Sbjct: 58  SSQPSLMALFMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAK 117

Query: 146 EEFQEHRVGRWVTVRTQDVCRSG-FGVSHVA--DAVFLDIPSPWEAVGHAWDALKVEGGR 202
                  V R        VC  G +GV   +  D +F+ +    + V   W     EGGR
Sbjct: 118 -----RNVERLGIENVIFVCGDGYYGVPEFSPYDVIFVTVGV--DEVPETWFTQLKEGGR 170


>1E6V-A nrPDB
          Length = 553

 Score = 27.3 bits (59), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 10/94 (10%)

Query: 142 EKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGG 201
           EK   E Q  ++ + +  RT  VCR    V HV D           A  + W A+++   
Sbjct: 188 EKLFPEEQAEQLIKAIGNRTYQVCRMPTIVGHVCDG----------ATMYRWAAMQIAMS 237

Query: 202 RFCSFSPCIEQVQRTCQALAARGFSELSTLEVLP 235
             C++     +   +  A A++    ++  E+LP
Sbjct: 238 FICAYKIAAGEAAVSDFAFASKHAEVINMGEMLP 271


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

5CCX-A nrPDB                                                          396   e-111
1O54-A nrPDB                                                          298   2e-81
3LGA-A nrPDB                                                          284   2e-77
5EQJ-B nrPDB                                                          278   2e-75
1I9G-A nrPDB                                                          262   1e-70
2YVL-A nrPDB                                                          232   1e-61
2B25-A nrPDB                                                          213   9e-56
2PWY-A nrPDB                                                          211   3e-55
1YB2-A nrPDB                                                          206   6e-54

Sequences not found previously or not previously below threshold:

1DL5-A nrPDB                                                           57   9e-09
2YXE-A nrPDB                                                           54   9e-08
1JG3-A nrPDB                                                           53   1e-07
3TFW-A nrPDB                                                           53   2e-07
4O29-A nrPDB                                                           53   2e-07
3DUW-A nrPDB                                                           49   2e-06
1KR5-A nrPDB                                                           48   4e-06
3MGG-A nrPDB                                                           48   5e-06
5BP7-A nrPDB                                                           48   6e-06
3LBF-A nrPDB                                                           47   9e-06
5X7F-A nrPDB                                                           45   4e-05
1VBF-A nrPDB                                                           44   5e-05
4L7V-A nrPDB                                                           44   6e-05
3BUS-A nrPDB                                                           44   1e-04
3BKX-A nrPDB                                                           44   1e-04
5N5D-A nrPDB                                                           43   1e-04
1YUB-A nrPDB                                                           43   1e-04
3CCF-A nrPDB                                                           43   2e-04
1NKV-A nrPDB                                                           43   2e-04
5EKU-A nrPDB                                                           41   6e-04
4M36-A nrPDB                                                           41   6e-04
3E05-A nrPDB                                                           41   7e-04
3EEY-A nrPDB                                                           41   8e-04
1UWV-A nrPDB                                                           40   0.001
3M6U-A nrPDB                                                           40   0.001
3TMA-A nrPDB                                                           40   0.001
2IPX-A nrPDB                                                           40   0.001
1R18-A nrPDB                                                           40   0.001
2PBF-A nrPDB                                                           39   0.002
3DLC-A nrPDB                                                           39   0.003
5BXY-A nrPDB                                                           39   0.003
3R3H-A nrPDB                                                           39   0.003
6EC3-A nrPDB                                                           38   0.004
5LOG-A nrPDB                                                           38   0.004
6BQC-A nrPDB                                                           38   0.004
3HM2-A nrPDB                                                           38   0.006
2PXX-A nrPDB                                                           38   0.006
2HNK-A nrPDB                                                           37   0.009
2AS0-A nrPDB                                                           37   0.011
4INE-A nrPDB                                                           37   0.011
4OA5-A nrPDB                                                           37   0.012
4DF3-A nrPDB                                                           36   0.014
5WYK-3B nrPDB                                                          36   0.015
3C3P-A nrPDB                                                           36   0.016
5EVJ-A nrPDB                                                           36   0.017
3M4X-A nrPDB                                                           36   0.017
5OQL-R nrPDB                                                           36   0.018
3CBG-A nrPDB                                                           36   0.021
4KDR-A nrPDB                                                           36   0.023
3VC2-A nrPDB                                                           36   0.026
3R9X-B nrPDB                                                           36   0.026
4PON-A nrPDB                                                           35   0.032
1SQG-A nrPDB                                                           35   0.034
1QAM-A nrPDB                                                           35   0.037
3EVZ-A nrPDB                                                           34   0.061
6IFX-A nrPDB                                                           34   0.062
5YLN-A nrPDB                                                           34   0.062
3NJR-A nrPDB                                                           34   0.068
2VS1-A nrPDB                                                           34   0.071
2B3T-A nrPDB                                                           34   0.071
3D2L-A nrPDB                                                           34   0.097
6IFV-A nrPDB                                                           33   0.11 
3R0Q-C nrPDB                                                           33   0.12 
1ZQ9-A nrPDB                                                           33   0.14 
1EIZ-A nrPDB                                                           33   0.20 
2NNW-B nrPDB                                                           33   0.22 
4FZV-A nrPDB                                                           33   0.23 
2YXD-A nrPDB                                                           33   0.23 
4KDC-A nrPDB                                                           32   0.28 
5WWT-A nrPDB                                                           31   0.44 
3DMF-A nrPDB                                                           31   0.45 
4F86-A nrPDB                                                           31   0.49 
4FS8-A nrPDB                                                           31   0.55 
5WP5-A nrPDB                                                           31   0.56 
5FUB-A nrPDB                                                           31   0.61 
3CJR-A nrPDB                                                           31   0.88 
4DZR-A nrPDB                                                           30   0.96 
3E23-A nrPDB                                                           30   1.0  
6H1E-A nrPDB                                                           30   1.3  
4JJI-A nrPDB                                                           30   1.5  
1TPY-A nrPDB                                                           29   2.1  
1VQ1-A nrPDB                                                           29   2.6  
3W53-A nrPDB                                                           29   3.3  
1F8F-A nrPDB                                                           29   3.3  
5TNX-A nrPDB                                                           28   4.0  

>5CCX-A nrPDB
          Length = 289

 Score =  396 bits (1017), Expect = e-111,   Method: Composition-based stats.
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60
           MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC
Sbjct: 1   MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC 60

Query: 61  GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120
           GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA
Sbjct: 61  GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA 120

Query: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180
           IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL
Sbjct: 121 IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180

Query: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240
           DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV
Sbjct: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV 240

Query: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289
           RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG
Sbjct: 241 RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289


>1O54-A nrPDB
          Length = 277

 Score =  298 bits (763), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 77/280 (27%), Positives = 130/280 (46%), Gaps = 27/280 (9%)

Query: 8   ELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVY 67
           + +K GD  +LS    +   V +++  +  T  G++  + ++  +  G  +    G   Y
Sbjct: 18  DTLKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGIIDLN-EVFEKGPGEIIRTSAGKKGY 76

Query: 68  VLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAP 127
           +L P+     +N+  RTQI+Y  D + I MML+++ G  + ++G GSG++   + R +  
Sbjct: 77  ILIPSLIDEIMNMKRRTQIVYPKDSSFIAMMLDVKEGDRIIDTGVGSGAMCAVLARAVGS 136

Query: 128 TGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWE 187
           +G +   E  ++ A+ A     +  +   VT++ +D+   GF    V DA+FLD+P PW 
Sbjct: 137 SGKVFAYEKREEFAKLAESNLTKWGLIERVTIKVRDIS-EGFDEKDV-DALFLDVPDPWN 194

Query: 188 AVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPP 247
            +   W+ALK  GGRF +  P   QVQ T + L    F  +   E L + Y       P 
Sbjct: 195 YIDKCWEALK-GGGRFATVCPTTNQVQETLKKLQELPFIRIEVWESLFRPYK------PV 247

Query: 248 PDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKT 287
           P+                    P+   V HT Y+ FATK 
Sbjct: 248 PE-----------------RLRPVDRMVAHTAYMIFATKV 270


>3LGA-A nrPDB
          Length = 253

 Score =  284 bits (727), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 77/279 (27%), Positives = 122/279 (43%), Gaps = 26/279 (9%)

Query: 9   LIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYV 68
           +I+EGD  +L    G    + V +     T  G+L+   ++IGR FG  +   +G    +
Sbjct: 1   MIREGDKVVLVDPRGKRYLITVSK-RDFHTDLGILKLE-EIIGRNFGEAIKSHKGHEFKI 58

Query: 69  LHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128
           L P    +   +    QI++  D ALI     + PG  + E+G GSG+++  +   + P 
Sbjct: 59  LRPRIVDYLDKMKRGPQIVHPKDAALIVAYAGISPGDFIVEAGVGSGALTLFLANIVGPE 118

Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188
           G + + E  +  A+ A E  +       VT++ +D+   G    +V D V LD+P P   
Sbjct: 119 GRVVSYEIREDFAKLAWENIKWAGFDDRVTIKLKDIY-EGIEEENV-DHVILDLPQPERV 176

Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248
           V HA  ALK  GG F +++PC  QV R  + L      E     + P+  NV        
Sbjct: 177 VEHAAKALK-PGGFFVAYTPCSNQVMRLHEKL-----REFKDYFMKPRTINVLVF----- 225

Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKT 287
                 D     +        P   A+ HTGY+TFA + 
Sbjct: 226 ------DQEVKKECM-----RPRTTALVHTGYITFARRI 253


>5EQJ-B nrPDB
          Length = 383

 Score =  278 bits (711), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 105/263 (39%), Positives = 149/263 (56%), Gaps = 28/263 (10%)

Query: 3   FVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVT--- 59
           F  Y++LIKEGD  ++ +    +  VR+       TR+G   H  D+IG+P+GS++    
Sbjct: 6   FSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRYGSFPHK-DIIGKPYGSQIAIRT 64

Query: 60  --CGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSV 117
               +  +V+VL PTPELWTL+LPHRTQI+Y+ D + I   L   P S V E+GTGSGS 
Sbjct: 65  KGSNKFAFVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSF 124

Query: 118 SHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-VGRWVTVRTQDVCRSGF------- 169
           SHA  R++   GHL + EFH  R E+A EEF+EH  +   VT+  +DVC+ GF       
Sbjct: 125 SHAFARSV---GHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRDVCQGGFLIKKGDT 181

Query: 170 ----------GVSHVADAVFLDIPSPWEAVGHAWDALKV-EGGRFCSFSPCIEQVQRTCQ 218
                       S  A+ VFLD+P+PW+A+ H    + V E    C FSPCIEQV +T  
Sbjct: 182 TSYEFGNNETAASLNANVVFLDLPAPWDAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLD 241

Query: 219 ALAARGFSELSTLEVLPQVYNVR 241
            L   G++++  +E+  + Y  R
Sbjct: 242 VLEKYGWTDVEMVEIQGRQYESR 264


>1I9G-A nrPDB
          Length = 280

 Score =  262 bits (668), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 70/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)

Query: 13  GDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPT 72
           G+   L+   G    + +  GA+  T  G + H   +IG   GS V    G    VL P 
Sbjct: 10  GERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDA-VIGLEQGSVVKSSNGALFLVLRPL 68

Query: 73  PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLH 132
              + +++P   Q++Y  D A I    ++ PG+ V E+G GSG+++ +++R + P G + 
Sbjct: 69  LVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVI 128

Query: 133 TVEFHQQRAEKAREEFQ---EHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189
           + E     AE AR             W  V   D+  S      V D   LD+ +PWE +
Sbjct: 129 SYEQRADHAEHARRNVSGCYGQPPDNWRLV-VSDLADSELPDGSV-DRAVLDMLAPWEVL 186

Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARG-FSELSTLEVLPQVYNVRTVSLPPP 248
             A   L V GG    +   + Q+ R  +AL A+  ++E    E L + +NV  +++   
Sbjct: 187 D-AVSRLLVAGGVLMVYVATVTQLSRIVEALRAKQCWTEPRAWETLQRGWNVVGLAV--- 242

Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286
                                P     GHT +L    +
Sbjct: 243 --------------------RPQHSMRGHTAFLVATRR 260


>2YVL-A nrPDB
          Length = 248

 Score =  232 bits (591), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 66/278 (23%), Positives = 114/278 (41%), Gaps = 37/278 (13%)

Query: 10  IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69
            KEG+  ++  G    +   + + + +  +  VL+   ++IG+P G K+    G  VY  
Sbjct: 4   FKEGEYVLIRFGEKKFLRKLLPKQSLS-VKKSVLKFD-EVIGKPEGVKIN---GFEVY-- 56

Query: 70  HPTPELW-TLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPT 128
            PT E    L    +TQI+Y  D   I + L L     V E GTGSG++  A++  +A  
Sbjct: 57  RPTLEEIILLGFERKTQIIYPKDSFYIALKLNLNKEKRVLEFGTGSGAL-LAVLSEVA-- 113

Query: 129 GHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188
           G + T E  ++  + A++  ++  +G+ V     D   +      +  A F+D+  PW  
Sbjct: 114 GEVWTFEAVEEFYKTAQKNLKKFNLGKNVKFFNVDFKDAEVPEG-IFHAAFVDVREPWHY 172

Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248
           +     +L +EG       P   QV +  +++    F  L  +E+L + Y          
Sbjct: 173 LEKVHKSL-MEGAPVGFLLPTANQVIKLLESIE-NYFGNLEVVEILHRHYK--------- 221

Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286
                         +      P  + V HT YL F  K
Sbjct: 222 --------------TISERFRPEDQMVAHTAYLVFGRK 245


>2B25-A nrPDB
          Length = 336

 Score =  213 bits (541), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 52/255 (20%), Positives = 100/255 (39%), Gaps = 18/255 (7%)

Query: 2   SFVAYEELIKEGDTAILSLGHGA---MVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKV 58
           S  + E   + G+  +   G G        R+       +  G +     ++G+  G  +
Sbjct: 2   SSTSRERPFQAGELILAETGEGETKFKKLFRLNNFGLLNSNWGAVPF-GKIVGKFPGQIL 60

Query: 59  TCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVS 118
               G    +  P  E + + +   T I +  DI +I  M+++ PG  V E+G+GSG +S
Sbjct: 61  RSSFGKQYMLRRPALEDYVVLMKRGTAITFPKDINMILSMMDINPGDTVLEAGSGSGGMS 120

Query: 119 HAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-------VGRW---VTVRTQDVCRSG 168
             + + +   G + + E  +   + A++ ++  R       V  W   V    +D+  + 
Sbjct: 121 LFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLSHVEEWPDNVDFIHKDISGAT 180

Query: 169 FGVSHVA-DAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALA--ARGF 225
             +  +  DAV LD+ +P   +   +  LK  GG    +   I QV      +       
Sbjct: 181 EDIKSLTFDAVALDMLNPHVTLPVFYPHLK-HGGVCAVYVVNITQVIELLDGIRTCELAL 239

Query: 226 SELSTLEVLPQVYNV 240
           S     EV+ + + V
Sbjct: 240 SCEKISEVIVRDWLV 254


>2PWY-A nrPDB
          Length = 258

 Score =  211 bits (537), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 65/277 (23%), Positives = 100/277 (36%), Gaps = 32/277 (11%)

Query: 16  AILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPEL 75
            +L    G    V  + G       G + H   L+    G  V    G  + V  PT E 
Sbjct: 10  LLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEA-LLEAGPGGVVRTHLGEELSVHRPTLEE 68

Query: 76  WTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVE 135
           + L++       Y  D + +  +L+L PG  V E+GTGSG ++  + R +   G + + E
Sbjct: 69  YLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYE 128

Query: 136 ---FHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHA 192
               H  +AE+    F +    R+   +               D V LD+  PW+ +  A
Sbjct: 129 ARPHHLAQAERNVRAFWQVENVRFHLGKL----EEAELEEAAYDGVALDLMEPWKVLEKA 184

Query: 193 WDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPDLGT 252
             ALK       ++ P I QV    +A  A  F     LEV  + + VR           
Sbjct: 185 ALALK-PDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVR----------- 232

Query: 253 GTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289
                            P  + VGHT +L    +  G
Sbjct: 233 ------------LPVAHPRFQQVGHTAFLVALRRWKG 257


>1YB2-A nrPDB
          Length = 275

 Score =  206 bits (525), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 29/238 (12%)

Query: 53  PFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGT 112
             G ++    G    V   +P  +   +   TQI+   D + I M   LRPG  + E G 
Sbjct: 61  EPGDELIVS-GKSFIVSDFSPMYFGRVIRRNTQIISEIDASYIIMRCGLRPGMDILEVGV 119

Query: 113 GSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE-HRVGRWVTVRTQDVCRSGFGV 171
           GSG++S  I+  +   G L  VE  +   +KA +   E + +G    VRT     + F  
Sbjct: 120 GSGNMSSYILYALNGKGTLTVVERDEDNLKKAMDNLSEFYDIG---NVRTSRSDIADFIS 176

Query: 172 SHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTL 231
             + DAV  DIP PW  V      +K  G     + P  +Q ++T  +L+A G   L T+
Sbjct: 177 DQMYDAVIADIPDPWNHVQKIASMMK-PGSVATFYLPNFDQSEKTVLSLSASGMHHLETV 235

Query: 232 EVLPQVYNVRTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG 289
           E++ +   VR           G   PA  D +             HT ++TFA K  G
Sbjct: 236 ELMKRRILVR----------EGATRPASDDLT-------------HTAFITFAIKKSG 270


>1DL5-A nrPDB
          Length = 317

 Score = 57.2 bits (136), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 35/171 (20%), Positives = 58/171 (33%), Gaps = 12/171 (7%)

Query: 39  RHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNL----PHRTQILYSTDIAL 94
           ++GV  H    I + F            Y L    E   L         +     + +AL
Sbjct: 11  KYGVSDH----IAKAFLEIPREEFLTKSYPLSYVYEDIVLVSYDDGEEYSTSSQPSLMAL 66

Query: 95  ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG 154
               + L  G  V E G G+G  +  + R +   G + +VE+ ++  E A+   +   + 
Sbjct: 67  FMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGI- 125

Query: 155 RWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCS 205
             V     D    G       D +F+ +    + V   W     EGGR   
Sbjct: 126 ENVIFVCGDGYY-GVPEFSPYDVIFVTVGV--DEVPETWFTQLKEGGRVIV 173


>2YXE-A nrPDB
          Length = 215

 Score = 53.7 bits (127), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 34/174 (19%), Positives = 56/174 (32%), Gaps = 18/174 (10%)

Query: 58  VTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIAL------------ITMMLELRPGS 105
           +   R     +  P  E    +L     +    +I              +  +L+L+PG 
Sbjct: 20  IKSKRVIDALLKVPREEFLPEHLKEYAYVDTPLEIGYGQTISAIHMVGMMCELLDLKPGM 79

Query: 106 VVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVC 165
            V E GTG G  +      +   G + ++E   + AEKA    ++      V V   D  
Sbjct: 80  KVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRKLGYD-NVIVIVGDGT 138

Query: 166 RSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQA 219
             G+      D ++     P +        LK  G       P    +QR   A
Sbjct: 139 L-GYEPLAPYDRIYTTAAGP-KIPEPLIRQLKDGGKLLM---PVGRYLQRLVLA 187


>1JG3-A nrPDB
          Length = 235

 Score = 53.3 bits (126), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 28/127 (22%), Positives = 52/127 (40%), Gaps = 5/127 (3%)

Query: 74  ELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT 133
               L +P    +     +A++  +  L+PG  + E GTGSG  +  I   +     ++T
Sbjct: 62  IDEPLPIPAGQTVSAPHMVAIMLEIANLKPGMNILEVGTGSGWNAALISEIV--KTDVYT 119

Query: 134 VEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAW 193
           +E   +  E A+   +   V + V V   D  + GF      D + +   +P +      
Sbjct: 120 IERIPELVEFAKRNLERAGV-KNVHVILGDGSK-GFPPKAPYDVIIVTAGAP-KIPEPLI 176

Query: 194 DALKVEG 200
           + LK+ G
Sbjct: 177 EQLKIGG 183


>3TFW-A nrPDB
          Length = 248

 Score = 52.9 bits (125), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153
            + +++ L     + E GT  G  +  + R +   G L T+E     A+ ARE  Q   V
Sbjct: 54  FLALLVRLTQAKRILEIGTLGGYSTIWMARELPADGQLLTLEADAHHAQVARENLQLAGV 113

Query: 154 GRWVTVRTQDV--CRSGFGVSHVADAVFLDIPSP 185
            + VT+R           G     D +F+D   P
Sbjct: 114 DQRVTLREGPALQSLESLGECPAFDLIFIDADKP 147


>4O29-A nrPDB
          Length = 208

 Score = 52.5 bits (124), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 5/151 (3%)

Query: 74  ELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT 133
           E   L L     I     +A++  ++E RPG  + E GTGSG  +      I   G ++T
Sbjct: 46  EDRPLPLFAGATISAPHMVAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYT 105

Query: 134 VEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAW 193
           +E  ++ A  A +  +       V V   D  + G       DA+ +   +  + +  A 
Sbjct: 106 IEIVKELAVFAAQNLERLGYWGVVEVYHGDGKK-GLEKHAPFDAIIVTAAA--DVIPPAL 162

Query: 194 DALKVEGGRFCSFSPCIEQVQRTCQALAARG 224
                +GG      P  E++ +    +  RG
Sbjct: 163 IRQLKDGGVMV--IPVEERLGQVLYKVVKRG 191


>3DUW-A nrPDB
          Length = 223

 Score = 49.1 bits (115), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 16/75 (21%), Positives = 36/75 (48%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146
           +  T    + ++++++    + E GT  G  +  + R ++  G + T+E  ++ A+ AR 
Sbjct: 42  VSPTQGKFLQLLVQIQGARNILEIGTLGGYSTIWLARGLSSGGRVVTLEASEKHADIARS 101

Query: 147 EFQEHRVGRWVTVRT 161
             +   +   V VRT
Sbjct: 102 NIERANLNDRVEVRT 116


>1KR5-A nrPDB
          Length = 226

 Score = 48.3 bits (113), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 23/126 (18%), Positives = 44/126 (34%), Gaps = 7/126 (5%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
           L  G+   + G+GSG ++    R +  TG +  ++  ++  + +    ++       + R
Sbjct: 75  LHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPTLLSSGR 134

Query: 161 TQDVCRS---GFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFS--PCIEQVQR 215
            Q V      G+      DA+ +   +P   V  A       GGR           Q+  
Sbjct: 135 VQLVVGDGRMGYAEEAPYDAIHVGAAAP--VVPQALIDQLKPGGRLILPVGPAGGNQMLE 192

Query: 216 TCQALA 221
               L 
Sbjct: 193 QYDKLQ 198


>3MGG-A nrPDB
          Length = 276

 Score = 47.9 bits (112), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 8/103 (7%)

Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQ 162
           PG+ V E+G G G+ +  + +   P   + +++   +  EKARE  +++ + + V     
Sbjct: 37  PGAKVLEAGCGIGAQTVILAKN-NPDAEITSIDISPESLEKARENTEKNGI-KNVKFLQA 94

Query: 163 DVCRSGFGVSHVADAVFL-----DIPSPWEAVGHAWDALKVEG 200
           ++    F  S   D +F+      + SP EA+      LK  G
Sbjct: 95  NIFSLPFEDSS-FDHIFVCFVLEHLQSPEEALKSLKKVLKPGG 136


>5BP7-A nrPDB
          Length = 271

 Score = 47.5 bits (111), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 38/224 (16%), Positives = 63/224 (28%), Gaps = 18/224 (8%)

Query: 64  GWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIR 123
               +  P     T +       +    +  +   L L PG+ V + G+GSG +     R
Sbjct: 20  FQSMLDIPRIFTITESAHRIHNPITPEKLTTLGAALRLEPGTRVLDLGSGSGEMLCTWAR 79

Query: 124 TIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183
                G    ++  Q    +A+   +E  V   VT    D              V   + 
Sbjct: 80  DHGIIGT--GIDMSQLFTAQAKLRAEELGVADRVTFIHGDASGYVSDDKA---GVAACVG 134

Query: 184 SPW------EAVGHAWDALKVEGGRFCS-----FSPCIEQVQRTCQALAARGF-SELSTL 231
           + W        +     +L+  G            P  E V R C A +   F      L
Sbjct: 135 ATWIGGGVAGTIELLARSLRPGGIILIGEPYWRQVPPTEDVARGCLANSTSDFLMLPELL 194

Query: 232 EVLPQ-VYNVRTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEA 274
               +  Y+V  + L   D     +         +    P  E 
Sbjct: 195 ASFGRLGYDVVEMVLADQDGWDRYEAAKWLTMRRWLEANPDDEL 238


>3LBF-A nrPDB
          Length = 210

 Score = 47.1 bits (110), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 33/141 (23%), Positives = 54/141 (38%), Gaps = 7/141 (4%)

Query: 78  LNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFH 137
           L +     I     +A +T +LEL P S V E GTGSG  +  +   +    H+ +VE  
Sbjct: 52  LPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQ---HVCSVERI 108

Query: 138 QQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALK 197
           +    +AR   +   +   V+ R  D  + G+      DA+ +    P   +  A     
Sbjct: 109 KGLQWQARRRLKNLDL-HNVSTRHGDGWQ-GWQARAPFDAIIVTAAPPE--IPTALMTQL 164

Query: 198 VEGGRFCSFSPCIEQVQRTCQ 218
            EGG          Q  +  +
Sbjct: 165 DEGGILVLPVGEEHQYLKRVR 185


>5X7F-A nrPDB
          Length = 235

 Score = 44.8 bits (104), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 29/134 (21%), Positives = 48/134 (35%), Gaps = 9/134 (6%)

Query: 81  PHRTQI----LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEF 136
              T I    +     AL+ ++ +L  G  V E GTG+G     ++  +   G L T++ 
Sbjct: 52  ERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDI 111

Query: 137 HQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFG--VSHVADAVFLDIPSPWEAVGHAWD 194
             +    AR+ F E  +G   T       +           D VF+D   P +   +  +
Sbjct: 112 EPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDA-DPIDQPDYVAE 170

Query: 195 --ALKVEGGRFCSF 206
              L   GG     
Sbjct: 171 GVRLLRSGGVIVVH 184


>1VBF-A nrPDB
          Length = 231

 Score = 44.4 bits (103), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 27/146 (18%), Positives = 52/146 (35%), Gaps = 11/146 (7%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153
            +   L+L  G  V E GTG G  +  I   +     + +VE +++    A +    +  
Sbjct: 61  FMLDELDLHKGQKVLEIGTGIGYYTALIAEIVD---KVVSVEINEKMYNYASKLLSYY-- 115

Query: 154 GRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQV 213
              + +   D    G+      D V +   +P   +   ++ LK  G         + +V
Sbjct: 116 -NNIKLILGDGTL-GYEEEKPYDRVVVWATAP-TLLCKPYEQLKEGG--IMILPIGVGRV 170

Query: 214 QRTCQALAARGFSELSTL-EVLPQVY 238
           Q+  + +       L  L EV+    
Sbjct: 171 QKLYKVIKKGNSPSLENLGEVMFGRI 196


>4L7V-A nrPDB
          Length = 225

 Score = 44.4 bits (103), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 78  LNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFH 137
           L +     I     +A +T +L L P + V E GTGSG  +  + + +    H+ TVE  
Sbjct: 67  LPIGQGQTISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVN---HVFTVERI 123

Query: 138 QQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180
           +     A+   ++  +   V+ +  D  + G+      DA+ +
Sbjct: 124 KTLQWDAKRRLKQLDI-YNVSTKHGDGWQ-GWPARGPFDAILV 164


>3BUS-A nrPDB
          Length = 273

 Score = 43.7 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 35/225 (15%), Positives = 62/225 (27%), Gaps = 35/225 (15%)

Query: 95  ITMMLELRPGSVVCESGTGSG--SVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152
           +  +L++R G  V + G G G  +V  A  R +     +  +   + +  +A        
Sbjct: 53  MIALLDVRSGDRVLDVGCGIGKPAVRLATARDV----RVTGISISRPQVNQANARATAAG 108

Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFLD----IPSPWEAVGHAWDALKVEGGR----FC 204
           +   VT    D     F  +       L+    +P    A+      L+  G      F 
Sbjct: 109 LANRVTFSYADAMDLPFEDASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIADFV 168

Query: 205 SFSPCIEQVQRTCQALAARG----FSELSTLEVLPQVYNVRTVSL--------PPPDLGT 252
             +P     +    A  A G       +   E   +   +   S         P      
Sbjct: 169 LLAPVEGAKKEAVDAFRAGGGVLSLGGIDEYESDVRQAELVVTSTVDISAQARPSLVKTA 228

Query: 253 GTDGPAGSDTSPFRSGTPMKEAVG---------HTGYLTFATKTP 288
                A S   PF     +   +            GY+    + P
Sbjct: 229 EAFENARSQVEPFMGAEGLDRMIATFRGLAEVPEAGYVLIGARKP 273


>3BKX-A nrPDB
          Length = 275

 Score = 43.7 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 18/95 (18%), Positives = 32/95 (33%), Gaps = 8/95 (8%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRA------EKAREE 147
            I    +++PG  + E G G G +S  +   +  +GH+  ++             +A   
Sbjct: 34  AIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTLGQAWNH 93

Query: 148 FQEHRVGRWVT--VRTQDVCRSGFGVSHVADAVFL 180
                +G  +T    T      G       D V L
Sbjct: 94  LLAGPLGDRLTVHFNTNLSDDLGPIADQHFDRVVL 128


>5N5D-A nrPDB
          Length = 226

 Score = 43.3 bits (100), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146
           + +    L+ ++  LR    + E GT  G  S  + R + P G L T+E+ +  AE A  
Sbjct: 45  VSAPQGKLLHLLARLRQARRILEIGTFGGYSSIWLARALPPDGRLVTIEWERSFAESAAS 104

Query: 147 EFQEHRV---GRWVTVRTQDVCRS-GFGVSHVADAVFLDIPSP 185
              E  V         R  D+  +     +   D VF+D   P
Sbjct: 105 RLAEAGVAHLVEQHVGRALDILPTLDRPGTAPFDMVFVDANKP 147


>1YUB-A nrPDB
          Length = 245

 Score = 43.3 bits (100), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/93 (18%), Positives = 35/93 (37%), Gaps = 6/93 (6%)

Query: 86  ILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAR 145
           +     +  I   L L+    V E GTG G ++  + +    +  + ++E        + 
Sbjct: 12  LTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKI---SKQVTSIELDSHLFNLSS 68

Query: 146 EEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAV 178
           E+ +   +   VT+  QD+ +  F        V
Sbjct: 69  EKLK---LNTRVTLIHQDILQFQFPNKQRYKIV 98


>3CCF-A nrPDB
          Length = 279

 Score = 42.5 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/142 (19%), Positives = 48/142 (33%), Gaps = 13/142 (9%)

Query: 95  ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQ--EHR 152
           +  +L  +PG  + + G G+G ++  I +       +   +      EKAR+ +      
Sbjct: 49  LLQLLNPQPGEFILDLGCGTGQLTEKIAQ---SGAEVLGTDNAATMIEKARQNYPHLHFD 105

Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSF--SPCI 210
           V      R      + F     ++A+   +  P  A+     ALK  G     F     I
Sbjct: 106 VADARNFRVDKPLDAVF-----SNAMLHWVKEPEAAIASIHQALKSGGRFVAEFGGKGNI 160

Query: 211 EQVQRTC-QALAARGFSELSTL 231
           + +      AL   G      L
Sbjct: 161 KYILEALYNALETLGIHNPQAL 182


>1NKV-A nrPDB
          Length = 256

 Score = 42.5 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 32/143 (22%), Positives = 52/143 (36%), Gaps = 12/143 (8%)

Query: 99  LELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVT 158
           L ++PG+ + + G+GSG +     R    TG    ++       +A+   +E  V   V 
Sbjct: 32  LRMKPGTRILDLGSGSGEMLCTWARDHGITGT--GIDMSSLFTAQAKRRAEELGVSERVH 89

Query: 159 VRTQDVCRSGFGVSHVADAVFLDIPSPW------EAVGHAWDALKVEGGRFCSFSPCIEQ 212
               D   +G+  +   D     + + W       A      +LK  GG      P   Q
Sbjct: 90  FIHNDA--AGYVANEKCDVAAC-VGATWIAGGFAGAEELLAQSLK-PGGIMLIGEPYWRQ 145

Query: 213 VQRTCQALAARGFSELSTLEVLP 235
           +  T +   A G S  S    LP
Sbjct: 146 LPATEEIAQACGVSSTSDFLTLP 168


>5EKU-A nrPDB
          Length = 390

 Score = 41.0 bits (94), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 2/68 (2%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153
              +   + P + V E G GSG +S    +       +  VE  ++ A+ ARE  + + +
Sbjct: 86  YEVLKKHVTPETGVLEIGAGSGLLSLMAAKL--GAKWVVAVEGSEELAKLARENIRANNM 143

Query: 154 GRWVTVRT 161
              V V  
Sbjct: 144 EHQVKVLH 151


>4M36-A nrPDB
          Length = 343

 Score = 41.0 bits (94), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 2/68 (2%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRV 153
              +   + P + V E G GSG +S    +       +  VE  ++ A+ ARE  + + +
Sbjct: 51  YEVLKKHVTPETGVLEIGAGSGLLSLMAAKL--GAKWVVAVEGSEELAKLARENIRANNM 108

Query: 154 GRWVTVRT 161
              V V  
Sbjct: 109 EHQVKVLH 116


>3E05-A nrPDB
          Length = 204

 Score = 40.6 bits (93), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 10/137 (7%)

Query: 93  ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152
           A+    L L+   V+ + G GS SVS      + P G +  +E + Q     R+  ++  
Sbjct: 30  AVTLSKLRLQDDLVMWDIGAGSASVSIE-ASNLMPNGRIFALERNPQYLGFIRDNLKKF- 87

Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFL----DIPSPWEAVGHAWDALKVEGGRFCSFSP 208
           V R VT+  +     G       D VF+     +    E +      LK EG      + 
Sbjct: 88  VARNVTL-VEAFAPEGLDDLPDPDRVFIGGSGGMLE--EIIDAVDRRLKSEG-VIVLNAV 143

Query: 209 CIEQVQRTCQALAARGF 225
            ++ + +  + L   G+
Sbjct: 144 TLDTLTKAVEFLEDHGY 160


>3EEY-A nrPDB
          Length = 197

 Score = 40.6 bits (93), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 7/63 (11%), Positives = 25/63 (39%)

Query: 98  MLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWV 157
            + ++ G  V ++  G+G+ +  +   +   G +   +   +      ++  +  +   V
Sbjct: 17  KMFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRV 76

Query: 158 TVR 160
           T+ 
Sbjct: 77  TLI 79


>1UWV-A nrPDB
          Length = 433

 Score = 40.2 bits (92), Expect = 0.001,   Method: Composition-based stats.
 Identities = 27/131 (20%), Positives = 52/131 (39%), Gaps = 8/131 (6%)

Query: 99  LELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVT 158
           L+++P   V +   G G+ +  +    A    +  VE      EK ++  + + + + VT
Sbjct: 282 LDVQPEDRVLDLFCGMGNFTLPLATQAAS---VVGVEGVPALVEKGQQNARLNGL-QNVT 337

Query: 159 VRTQDVCRSGFG---VSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQR 215
              +++           +  D V LD P+   A G     +K+E  R    S     + R
Sbjct: 338 FYHENLEEDVTKQPWAKNGFDKVLLD-PARAGAAGVMQQIIKLEPIRIVYVSCNPATLAR 396

Query: 216 TCQALAARGFS 226
             +AL   G++
Sbjct: 397 DSEALLKAGYT 407


>3M6U-A nrPDB
          Length = 464

 Score = 39.8 bits (91), Expect = 0.001,   Method: Composition-based stats.
 Identities = 18/97 (18%), Positives = 30/97 (30%), Gaps = 2/97 (2%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146
           +       + ++L+ +PG  V +     G  +  +   +   G L   E   +R     E
Sbjct: 85  IQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLANEVDGKRVRGLLE 144

Query: 147 EFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183
             +       VT          FG       V LD P
Sbjct: 145 NVERWGAPLAVTQAPPRALAEAFGTY--FHRVLLDAP 179


>3TMA-A nrPDB
          Length = 354

 Score = 39.8 bits (91), Expect = 0.001,   Method: Composition-based stats.
 Identities = 15/59 (25%), Positives = 28/59 (47%)

Query: 89  STDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147
                 +  + + RPG  V +  TGSG+++     T+ PT  ++  +  ++R   ARE 
Sbjct: 189 PVLAQALLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLAREA 247


>2IPX-A nrPDB
          Length = 233

 Score = 39.8 bits (91), Expect = 0.001,   Method: Composition-based stats.
 Identities = 27/160 (16%), Positives = 53/160 (33%), Gaps = 4/160 (2%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
           ++PG+ V   G  SG+    +   + P G ++ VEF   R+ +      + R      + 
Sbjct: 75  IKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSH-RSGRDLINLAKKRTNIIPVIE 133

Query: 161 TQDVCRSGFGVSHVADAVFLDIPSPWE---AVGHAWDALKVEGGRFCSFSPCIEQVQRTC 217
                     +  + D +F D+  P +      +A   L+  G    S          + 
Sbjct: 134 DARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASA 193

Query: 218 QALAARGFSELSTLEVLPQVYNVRTVSLPPPDLGTGTDGP 257
           +A+ A    ++    + PQ             +  G   P
Sbjct: 194 EAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRP 233


>1R18-A nrPDB
          Length = 227

 Score = 39.8 bits (91), Expect = 0.001,   Method: Composition-based stats.
 Identities = 15/93 (16%), Positives = 37/93 (39%), Gaps = 8/93 (8%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTG-----HLHTVEFHQQRAEKAREEFQEHR--- 152
           L+PG+ + + G+GSG ++    R I   G      +  +E   +   +++          
Sbjct: 82  LKPGARILDVGSGSGYLTACFYRYIKAKGVDADTRIVGIEHQAELVRRSKANLNTDDRSM 141

Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSP 185
           +     +  +   R G+  +   +A+ +   +P
Sbjct: 142 LDSGQLLIVEGDGRKGYPPNAPYNAIHVGAAAP 174


>2PBF-A nrPDB
          Length = 227

 Score = 39.1 bits (89), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/144 (14%), Positives = 49/144 (34%), Gaps = 17/144 (11%)

Query: 39  RHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMM 98
           R G++    D+    + + +   RG   Y+         + + H   I      AL    
Sbjct: 21  RRGIID-DDDV----YNTMLQVDRGK--YIKEIPYIDTPVYISHGVTISAPHMHALSLKR 73

Query: 99  L--ELRPGSVVCESGTGSGSVSHAIIRTI----APTGHLHTVEFHQQRAEKAREEFQEHR 152
           L   L+PGS   + G+GSG ++  +   +        ++  +E  +     + E  +  +
Sbjct: 74  LINVLKPGSRAIDVGSGSGYLTVCMAIKMNVLENKNSYVIGLERVKDLVNFSLENIKRDK 133

Query: 153 VG----RWVTVRTQDVCRSGFGVS 172
                     +  +++ +      
Sbjct: 134 PELLKIDNFKIIHKNIYQVNEEEK 157


>3DLC-A nrPDB
          Length = 219

 Score = 39.1 bits (89), Expect = 0.003,   Method: Composition-based stats.
 Identities = 13/80 (16%), Positives = 27/80 (33%), Gaps = 3/80 (3%)

Query: 85  QILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKA 144
             +Y      I     +  G    + G+G G++S A+ +    +        H    E A
Sbjct: 26  APIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSDFSIRALDFSKHMN--EIA 82

Query: 145 REEFQEHRVGRWVTVRTQDV 164
            +   +  +   + +   DV
Sbjct: 83  LKNIADANLNDRIQIVQGDV 102


>5BXY-A nrPDB
          Length = 158

 Score = 38.7 bits (88), Expect = 0.003,   Method: Composition-based stats.
 Identities = 17/80 (21%), Positives = 32/80 (40%), Gaps = 2/80 (2%)

Query: 95  ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG 154
           +  + ++    V+ + G+G G +     RT    G    +E      +KAR+  +E  V 
Sbjct: 16  MLELADVDETDVLYDLGSGDGRIVIRAARTHGARG--VGIEIDPDLVKKARKNAKEAGVA 73

Query: 155 RWVTVRTQDVCRSGFGVSHV 174
             V  R  D+  +    + V
Sbjct: 74  DLVEFRQGDLFEADISEATV 93


>3R3H-A nrPDB
          Length = 242

 Score = 38.7 bits (88), Expect = 0.003,   Method: Composition-based stats.
 Identities = 21/117 (17%), Positives = 42/117 (35%), Gaps = 6/117 (5%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKA-- 144
           +       + M++ L     V E GT +G  + A+   +   G + T + ++   + A  
Sbjct: 44  VAPEQAQFMQMLIRLTRAKKVLELGTFTGYSALAMSLALPDDGQVITCDINEGWTKHAHP 103

Query: 145 -REEFQEHRVGRWVTVRTQDV--CRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKV 198
              E ++    +       D        G  H  D +F+D       + +   ALK+
Sbjct: 104 YWREAKQEHKIKLRLGPALDTLHSLLNEGGEHQFDFIFIDA-DKTNYLNYYELALKL 159


>6EC3-A nrPDB
          Length = 471

 Score = 38.3 bits (87), Expect = 0.004,   Method: Composition-based stats.
 Identities = 21/100 (21%), Positives = 36/100 (36%), Gaps = 9/100 (9%)

Query: 102 RPGS-VVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
            PG+  + E G   G+ + A+ R    +  +  +E  ++   +A    + H     V +R
Sbjct: 73  FPGATRILELGALEGADTLALARQPGTS--ILGLEGREENLRRAEFVMEVHG-ATNVELR 129

Query: 161 TQDVCRSGFGVSHVADAVFL-----DIPSPWEAVGHAWDA 195
             DV    F      DAV        +  PW  +  A   
Sbjct: 130 IADVETLDFATLGRFDAVLCAGLLYHVREPWALLKDAARV 169


>5LOG-A nrPDB
          Length = 233

 Score = 38.3 bits (87), Expect = 0.004,   Method: Composition-based stats.
 Identities = 23/114 (20%), Positives = 39/114 (34%), Gaps = 5/114 (4%)

Query: 73  PELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLH 132
               T  LP RT  +      L+++++ L       E G  +G  +      +   G + 
Sbjct: 29  LREETSKLPLRTMQIPPEQGQLLSLLVRLIGARKTLEVGVFTGYSTLCTALALPADGRVI 88

Query: 133 TVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRS-----GFGVSHVADAVFLD 181
             +  ++    AR  +Q   V   + VR  D   S     G       D  F+D
Sbjct: 89  ACDLSEEWVSIARRYWQRAGVADRIEVRLGDAHHSLEALVGSEHRGTFDLAFID 142


>6BQC-A nrPDB
          Length = 383

 Score = 38.3 bits (87), Expect = 0.004,   Method: Composition-based stats.
 Identities = 23/115 (20%), Positives = 38/115 (33%), Gaps = 13/115 (11%)

Query: 94  LITMMLELRPGSVVCESGTGSGSVSHAII--RTIAPTGHLHTVEFHQQRAEKAREEFQEH 151
           +I   L+L+PG  V + G G G ++H +     ++  G   + E  +   E+        
Sbjct: 159 MICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCE------ 212

Query: 152 RVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWE---AVGHAWDALKVEGGRF 203
             G  VT+  QD          +      +   P             LK EG   
Sbjct: 213 --GLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFL 265


>3HM2-A nrPDB
          Length = 178

 Score = 37.9 bits (86), Expect = 0.006,   Method: Composition-based stats.
 Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 7/157 (4%)

Query: 93  ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152
           AL    L  +P   + + G GSGS++   +R+  P       E  ++R E+         
Sbjct: 15  ALAISALAPKPHETLWDIGGGSGSIAIEWLRST-PQTTAVCFEISEERRERILSNAINLG 73

Query: 153 VGRWVTVRTQDVCRSGFGVSHVADAVFL--DIPSPWEAVGHAWDALKVEGGRFCSFSPCI 210
           V   + V+ Q   R+   V    D +F+   + +P      AW  L V GGR  + +  +
Sbjct: 74  VSDRIAVQ-QGAPRAFDDVPDNPDVIFIGGGLTAP-GVFAAAWKRLPV-GGRLVANAVTV 130

Query: 211 EQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPP 247
           E  ++   AL  +    +S+  +  +      +++ P
Sbjct: 131 E-SEQMLWALRKQFGGTISSFAISHEHTVGSFITMKP 166


>2PXX-A nrPDB
          Length = 215

 Score = 37.5 bits (85), Expect = 0.006,   Method: Composition-based stats.
 Identities = 28/150 (18%), Positives = 51/150 (34%), Gaps = 17/150 (11%)

Query: 92  IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH 151
                +  ELRP   +   G G+ ++S+ +   +    ++ +V++        +  +   
Sbjct: 31  SFRALLEPELRPEDRILVLGCGNSALSYELF--LGGFPNVTSVDYSSVVVAAMQACYAHV 88

Query: 152 RVGRWVTVRTQ--DVCRSGFG---VSHVADAVFLDIPSPW-------EAVGHA---WDAL 196
              RW T+  +  D   + F         DA+      PW         V         +
Sbjct: 89  PQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRV 148

Query: 197 KVEGGRFCSFSPCIEQVQRTCQALAARGFS 226
            V GGRF S +      +    A A  G+S
Sbjct: 149 LVPGGRFISMTSAAPHFRTRHYAQAYYGWS 178


>2HNK-A nrPDB
          Length = 239

 Score = 37.1 bits (84), Expect = 0.009,   Method: Composition-based stats.
 Identities = 9/75 (12%), Positives = 31/75 (41%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146
           +   +   + ++ ++     + E GT +G  S      +   G +   +  ++    AR+
Sbjct: 44  ISPEEGQFLNILTKISGAKRIIEIGTFTGYSSLCFASALPEDGKILCCDVSEEWTNVARK 103

Query: 147 EFQEHRVGRWVTVRT 161
            ++E+ +   + ++ 
Sbjct: 104 YWKENGLENKIFLKL 118


>2AS0-A nrPDB
          Length = 396

 Score = 36.7 bits (83), Expect = 0.011,   Method: Composition-based stats.
 Identities = 23/138 (16%), Positives = 49/138 (35%), Gaps = 6/138 (4%)

Query: 51  GRPFGSKVTCGRGGWVYVLHPTPELWTLNLP-HRTQILYSTDIALITMMLELRPGSVVCE 109
           G P   +V  G+  +  ++      + +++   +T          + +   ++PG  V +
Sbjct: 164 GLPEIERVLLGKEKYRTIIQEGRAKFIVDMRGQKTGFFLDQRENRLALEKWVQPGDRVLD 223

Query: 110 SGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGF 169
             T +G    AI   IA    +  ++   +  E A+E  + + V   +            
Sbjct: 224 VFTYTGGF--AIHAAIAGADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSAFEEME 281

Query: 170 GV---SHVADAVFLDIPS 184
            +       D V LD P+
Sbjct: 282 KLQKKGEKFDIVVLDPPA 299


>4INE-A nrPDB
          Length = 454

 Score = 36.7 bits (83), Expect = 0.011,   Method: Composition-based stats.
 Identities = 24/123 (19%), Positives = 40/123 (32%), Gaps = 9/123 (7%)

Query: 88  YSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147
           Y  ++ +I    + +PG  + + G G G  +  +        H+H ++        A E 
Sbjct: 226 YDENLKIIKRFGDFKPGQTMLDIGVGIGGGARQVADEFGV--HVHGIDLSSNMLAIALER 283

Query: 148 FQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL-----DIPSPWEAVGHAWDALKVEGGR 202
             E      V     D     F   +  D VF       IP   +     + ALK  G  
Sbjct: 284 LHE-EKDSRVKYSITDALVYQF-EDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKV 341

Query: 203 FCS 205
             +
Sbjct: 342 LIT 344


>4OA5-A nrPDB
          Length = 227

 Score = 36.7 bits (83), Expect = 0.012,   Method: Composition-based stats.
 Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 2/77 (2%)

Query: 107 VCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQD--V 164
           + E GT  G  +  +   +   GH++T+E   +    A +     ++   +TV   +   
Sbjct: 69  IVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALA 128

Query: 165 CRSGFGVSHVADAVFLD 181
             +        D +F+D
Sbjct: 129 QLNTLKEMAPFDMIFID 145


>4DF3-A nrPDB
          Length = 233

 Score = 36.4 bits (82), Expect = 0.014,   Method: Composition-based stats.
 Identities = 17/98 (17%), Positives = 34/98 (34%), Gaps = 11/98 (11%)

Query: 96  TMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGR 155
            + L ++ G  +   G  SG+ +  +   I P G ++ VE     A +   +       R
Sbjct: 70  LIELPVKEGDRILYLGIASGTTASHMSDIIGPRGRIYGVE----FAPRVMRDLLTVVRDR 125

Query: 156 WVTVRTQDVCRSGFGVS-----HVADAVFLDIPSPWEA 188
                   +  + F           D ++ D+  P +A
Sbjct: 126 RNIFPI--LGDARFPEKYRHLVEGVDGLYADVAQPEQA 161


>5WYK-3B nrPDB
          Length = 327

 Score = 36.4 bits (82), Expect = 0.015,   Method: Composition-based stats.
 Identities = 38/181 (20%), Positives = 62/181 (34%), Gaps = 24/181 (13%)

Query: 71  PTPELWTLNLPHRTQILYSTDIALITMMLE---LRPGSVVCESGTGSGSVSHAIIRTIAP 127
           PT   + +  P R+++      A I   L+   + PG  V   G  SG+    +   + P
Sbjct: 136 PTKVEYRVWNPFRSKL-----AAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGP 190

Query: 128 TGHLHTVEFHQQRAEKAREEFQEHRVGRWV--TVRTQDVCRSGFGVSHVADAVFLDIPSP 185
            G ++ VEF  +   +     ++      +    R     R   G   + D VF D+  P
Sbjct: 191 EGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIG---MVDCVFADVAQP 247

Query: 186 WEA---VGHAWDALKVEGGRFCSFSPCI--------EQVQRTCQALAARGFSELSTLEVL 234
            +A     ++   LK +GG   S                 R  Q L       L  L + 
Sbjct: 248 DQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLE 307

Query: 235 P 235
           P
Sbjct: 308 P 308


>3C3P-A nrPDB
          Length = 210

 Score = 36.4 bits (82), Expect = 0.016,   Method: Composition-based stats.
 Identities = 22/130 (16%), Positives = 47/130 (36%), Gaps = 6/130 (4%)

Query: 57  KVTCGRGGWVYVLHPTPELWTLNLP-----HRTQILYSTDIALITMMLELRPGSVVCESG 111
            V    G ++  L P  +     +          I+      L+ ++  ++   +V   G
Sbjct: 5   IVDSRIGAYLDGLLPEADPVVAAMEQIARERNIPIVDRQTGRLLYLLARIKQPQLVVVPG 64

Query: 112 TGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGV 171
            G G  S    R I+ +  +  ++  +   E AR    ++ +   V ++  D      G 
Sbjct: 65  DGLGCASWWFARAISISSRVVMIDPDRDNVEHARRMLHDNGLIDRVELQVGDPLGIAAGQ 124

Query: 172 SHVADAVFLD 181
             + D +F+D
Sbjct: 125 RDI-DILFMD 133


>5EVJ-A nrPDB
          Length = 387

 Score = 36.4 bits (82), Expect = 0.017,   Method: Composition-based stats.
 Identities = 18/111 (16%), Positives = 38/111 (34%), Gaps = 13/111 (11%)

Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGR------- 155
            G  V + G GSG  ++   + +   G +  V+    + E A      +   +       
Sbjct: 83  EGLRVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTPAQLEVAISHADAYARDKLGYGKSN 142

Query: 156 --WVTVRTQDVCRSGFGVSH----VADAVFLDIPSPWEAVGHAWDALKVEG 200
             ++    + + R+G   S     +++ V    P     +  A+  L   G
Sbjct: 143 MTFIQGEIEYLDRAGLEDSSFDLVISNCVINLSPDKARVLSEAYRVLAPGG 193


>3M4X-A nrPDB
          Length = 456

 Score = 36.4 bits (82), Expect = 0.017,   Method: Composition-based stats.
 Identities = 18/93 (19%), Positives = 29/93 (31%), Gaps = 2/93 (2%)

Query: 92  IALIT-MMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE 150
            A+I       +PG  V +     G  S  +   +   G L T E   +RA+   E  + 
Sbjct: 93  SAMIVGTAAAAKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIER 152

Query: 151 HRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183
             V   +                  D + +D P
Sbjct: 153 WGVSNAIVTNHAPAELVPHFSG-FFDRIVVDAP 184


>5OQL-R nrPDB
          Length = 313

 Score = 36.0 bits (81), Expect = 0.018,   Method: Composition-based stats.
 Identities = 20/85 (23%), Positives = 34/85 (40%), Gaps = 1/85 (1%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
           ++PGS V   G  SG+    +   + PTG ++ VEF   R+ +        R      V 
Sbjct: 150 MKPGSKVLYLGAASGTSVSHVADIVGPTGAVYAVEFSH-RSGRDLINMATRRTNVIPIVE 208

Query: 161 TQDVCRSGFGVSHVADAVFLDIPSP 185
                 +   +  + D +F D+  P
Sbjct: 209 DARKPMAYRMLVPMVDVIFADVAQP 233


>3CBG-A nrPDB
          Length = 232

 Score = 36.0 bits (81), Expect = 0.021,   Method: Composition-based stats.
 Identities = 15/86 (17%), Positives = 33/86 (38%)

Query: 76  WTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVE 135
            T +LP     +       + +++ L     V E G   G  + A+   + P G +   +
Sbjct: 45  ETAHLPGAPMQISPEQAQFLGLLISLTGAKQVLEIGVFRGYSALAMALQLPPDGQIIACD 104

Query: 136 FHQQRAEKAREEFQEHRVGRWVTVRT 161
                   A++ +Q+  V   +++R 
Sbjct: 105 QDPNATAIAKKYWQKAGVAEKISLRL 130


>4KDR-A nrPDB
          Length = 223

 Score = 35.6 bits (80), Expect = 0.023,   Method: Composition-based stats.
 Identities = 25/142 (17%), Positives = 44/142 (30%), Gaps = 3/142 (2%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAP-TGHLHTVEFHQQRAEKAR 145
           +    +  I        G  V + G G G ++ ++ R  A  TG     E  Q     A 
Sbjct: 46  INPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHAL 105

Query: 146 EEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCS 205
           E   +    +  TV       +G         +   +P P   V      +K  G  F  
Sbjct: 106 ESGIQVDYVQE-TVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVF-F 163

Query: 206 FSPCIEQVQRTCQALAARGFSE 227
            +     V++  +     G+ +
Sbjct: 164 STLNRNGVKKFIKPAELLGWVD 185


>3VC2-A nrPDB
          Length = 312

 Score = 35.6 bits (80), Expect = 0.026,   Method: Composition-based stats.
 Identities = 25/201 (12%), Positives = 57/201 (28%), Gaps = 33/201 (16%)

Query: 33  GAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDI 92
                  +G+       +G P  S+        ++ L      + ++             
Sbjct: 64  DGLYHHHYGIGPVDRAALGDPEHSEYEKKVIAELHRLESAQAEFLMD------------- 110

Query: 93  ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152
                + +  P   + ++G G G       R       +  V     +A+      +E R
Sbjct: 111 ----HLGQAGPDDTLVDAGCGRGGSMVMAHRRFGS--RVEGVTLSAAQADFGNRRARELR 164

Query: 153 VGRWVTVRTQDVCRSGFGVSHVA------DAVFLDIPSPWEAVGHAWDALKVEGGRFCSF 206
           +   V  R  ++  + F    V         +++D+      +          GGR+ + 
Sbjct: 165 IDDHVRSRVCNMLDTPFDKGAVTASWNNESTMYVDLHD----LFSEHSRFLKVGGRYVTI 220

Query: 207 SPCIE----QVQRTCQALAAR 223
           + C      Q  +    + A 
Sbjct: 221 TGCWNPRYGQPSKWVSQINAH 241


>3R9X-B nrPDB
          Length = 248

 Score = 35.6 bits (80), Expect = 0.026,   Method: Composition-based stats.
 Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 7/71 (9%)

Query: 95  ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG 154
           I   L +  G+ V E G G+G+++  +++   P   L+ +E  ++      E  +     
Sbjct: 22  IAEELNIEEGNTVVEVGGGTGNLTKVLLQ--HPLKKLYVIELDREM----VENLKSIG-D 74

Query: 155 RWVTVRTQDVC 165
             + V  +D  
Sbjct: 75  ERLEVINEDAS 85


>4PON-A nrPDB
          Length = 200

 Score = 35.2 bits (79), Expect = 0.032,   Method: Composition-based stats.
 Identities = 8/55 (14%), Positives = 22/55 (40%)

Query: 96  TMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE 150
            + +    G +V ++  G+G  +  +   +   GH++  +  +      +E   E
Sbjct: 19  LLKMAAGEGDIVIDATMGNGHDTQFLAELVGENGHVYAFDIQESAVANTKERLGE 73


>1SQG-A nrPDB
          Length = 429

 Score = 35.2 bits (79), Expect = 0.034,   Method: Composition-based stats.
 Identities = 25/121 (20%), Positives = 43/121 (35%), Gaps = 8/121 (6%)

Query: 66  VYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRP--GSVVCESGTGSGSVSHAIIR 123
           V +  P P             +   D +    M  L P  G  + +     G  +  I+ 
Sbjct: 209 VRLETPAPVHALPGFEDGWVTV--QDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHIL- 265

Query: 124 TIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQD-VCRSGFGVSHVADAVFLDI 182
            +AP   +  V+  +QR  +  +  +  R+G   TV+  D    S +      D + LD 
Sbjct: 266 EVAPEAQVVAVDIDEQRLSRVYDNLK--RLGMKATVKQGDGRYPSQWCGEQQFDRILLDA 323

Query: 183 P 183
           P
Sbjct: 324 P 324


>1QAM-A nrPDB
          Length = 244

 Score = 35.2 bits (79), Expect = 0.037,   Method: Composition-based stats.
 Identities = 18/106 (16%), Positives = 39/106 (36%), Gaps = 8/106 (7%)

Query: 79  NLPHRTQILYST-DIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFH 137
           N+ H    + S  +I  I   + L     + E G+G G  +  +   +     +  +E  
Sbjct: 5   NIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLEL---VQRCNFVTAIEID 61

Query: 138 QQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183
            +  +    +  +H       V  +D+ +  F  +     +F +IP
Sbjct: 62  HKLCKTTENKLVDH---DNFQVLNKDILQFKFPKNQSY-KIFGNIP 103


>3EVZ-A nrPDB
          Length = 230

 Score = 34.4 bits (77), Expect = 0.061,   Method: Composition-based stats.
 Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 2/77 (2%)

Query: 75  LWTLNLPHRTQ-ILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT 133
           L+ L++ +  + ++ +     I +   LR G V  E GTG  ++   +         +  
Sbjct: 26  LFGLDIEYHPKGLVTTPISRYIFLKTFLRGGEVALEIGTGHTAMMALMAEKFFNC-KVTA 84

Query: 134 VEFHQQRAEKAREEFQE 150
            E  ++  E AR   + 
Sbjct: 85  TEVDEEFFEYARRNIER 101


>6IFX-A nrPDB
          Length = 287

 Score = 34.4 bits (77), Expect = 0.062,   Method: Composition-based stats.
 Identities = 31/204 (15%), Positives = 73/204 (35%), Gaps = 26/204 (12%)

Query: 73  PELWTLNLPHRTQILYSTDIAL---ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTG 129
            + +  +        +  D  +   I    E+   + V E G G G+++  + +      
Sbjct: 15  LKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAK---RAK 71

Query: 130 HLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGF-----GVSHVADAVFLDIPS 184
            +   E  Q+     ++    +     VTV  QDV ++             D + +    
Sbjct: 72  KVVAFEIDQRLLPILKDTLSPY---ENVTVIHQDVLKADVKSVIEEQFQDCDEIMVVANL 128

Query: 185 PWEA-----VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALA--ARGFSELSTLEVLPQV 237
           P+       +    + L ++G          E++  T ++L+   + ++E  T+ ++P  
Sbjct: 129 PYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMANTKRSLSIAVQFYTEAKTVMIVP-- 186

Query: 238 YNVRTVSLPPPDLGTGTDGPAGSD 261
              +TV +P P++ +        D
Sbjct: 187 ---KTVFVPQPNVDSAVIRLILRD 207


>5YLN-A nrPDB
          Length = 356

 Score = 34.4 bits (77), Expect = 0.062,   Method: Composition-based stats.
 Identities = 32/179 (17%), Positives = 59/179 (32%), Gaps = 20/179 (11%)

Query: 10  IKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVL 69
            K+GD  ++S             G     + G+  H  D  G  FG  +   +  ++ V 
Sbjct: 80  FKKGDKVLIS--------CVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQAEYLRVP 131

Query: 70  HP------TPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIR 123
           H       TPE  +         +  T   +  +  ++ PG  V   G+G   ++  +  
Sbjct: 132 HADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAIIGSGPVGLAALLTA 191

Query: 124 TIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDI 182
                  L  V+    R E A         G    V + D  ++   +  + D   +D+
Sbjct: 192 QFYSPAKLIMVDLDDNRLETALS------FGATHKVNSSDPEKAIKEIYDLTDGRGVDV 244


>3NJR-A nrPDB
          Length = 204

 Score = 34.0 bits (76), Expect = 0.068,   Method: Composition-based stats.
 Identities = 27/109 (24%), Positives = 37/109 (33%), Gaps = 14/109 (12%)

Query: 80  LPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQ 139
             H  QI  S   AL    L  R G ++ + G GSGSVS          G   T+E    
Sbjct: 32  FAHDGQITKSPMRALTLAALAPRRGELLWDIGGGSGSVSVEWCLA---GGRAITIEPRAD 88

Query: 140 RAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEA 188
           R E  ++    + +   +             V   A A   D+P P   
Sbjct: 89  RIENIQKNIDTYGLSPRMR-----------AVQGTAPAALADLPLPEAV 126


>2VS1-A nrPDB
          Length = 425

 Score = 34.0 bits (76), Expect = 0.071,   Method: Composition-based stats.
 Identities = 24/149 (16%), Positives = 45/149 (30%), Gaps = 13/149 (8%)

Query: 63  GGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAII 122
           G            + ++     Q      + L+  + EL  G  + +  +G G+    + 
Sbjct: 250 GKEFIRERLDDVDYLIHPNSFFQTNSYQAVNLVRKVSELVEGEKILDMYSGVGTFGIYLA 309

Query: 123 -RTIAPTGHLHTVEFHQQRAEKAREEFQEHRVG-RWVTVRTQDVCRSGFGVSHVADAVFL 180
            R     G     + ++   E AR   + + V   +     ++V   GF      D V +
Sbjct: 310 KRGFNVKG----FDSNEFAIEMARRNVEINNVDAEFEVASDREVSVKGF------DTVIV 359

Query: 181 DIPSPWEAVGHAWDALKVEGGRFCSFSPC 209
           D P            L  E      +  C
Sbjct: 360 DPPRAGLH-PRLVKRLNREKPGVIVYVSC 387


>2B3T-A nrPDB
          Length = 276

 Score = 34.0 bits (76), Expect = 0.071,   Method: Composition-based stats.
 Identities = 27/190 (14%), Positives = 56/190 (29%), Gaps = 16/190 (8%)

Query: 16  AILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPEL 75
            +L    G      +  G    T     +    L  R  G  +    G   +   P    
Sbjct: 26  ILLEHVTGRGRTFILAFGETQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVS 85

Query: 76  WTLNLPHRTQILYSTDIALITMMLELRPGS--VVCESGTGSGSVSHAIIRTIAPTGHLHT 133
               +P            L+   L   P     + + GTG+G+++ A+     P   +  
Sbjct: 86  PATLIPR------PDTECLVEQALARLPEQPCRILDLGTGTGAIALALASE-RPDCEIIA 138

Query: 134 VEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAW 193
           V+        A+   Q       + ++   + +S +  +       + + +P   +    
Sbjct: 139 VDRMPDAVSLAQRNAQH------LAIKNIHILQSDWFSALAGQQFAMIVSNP-PYIDEQD 191

Query: 194 DALKVEGGRF 203
             L+    RF
Sbjct: 192 PHLQQGDVRF 201


>3D2L-A nrPDB
          Length = 243

 Score = 33.7 bits (75), Expect = 0.097,   Method: Composition-based stats.
 Identities = 31/156 (19%), Positives = 55/156 (35%), Gaps = 29/156 (18%)

Query: 88  YSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147
           Y   +A +   +E  PG  + + G G+G+ +  +      TG   + E  +   EKA E 
Sbjct: 20  YPEWVAWVLEQVE--PGKRIADIGCGTGTATLLLADHYEVTGVDLSEEMLEIAQEKAMET 77

Query: 148 FQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFS 207
                  R V    QD+               L++P P +A+    D+L         + 
Sbjct: 78  ------NRHVDFWVQDMRE-------------LELPEPVDAITILCDSLN--------YL 110

Query: 208 PCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTV 243
                V++T  + A         L  +   Y + T+
Sbjct: 111 QTEADVKQTFDSAARLLTDGGKLLFDVHSPYKMETL 146


>6IFV-A nrPDB
          Length = 215

 Score = 33.3 bits (74), Expect = 0.11,   Method: Composition-based stats.
 Identities = 24/152 (15%), Positives = 50/152 (32%), Gaps = 21/152 (13%)

Query: 73  PELWTLNLPHRTQILYSTDIAL---ITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTG 129
            + +  +        +  D  +   I    E+   + V E G G G+++  + +      
Sbjct: 15  LKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAK---RAK 71

Query: 130 HLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAV 189
            +   E  Q+     ++    +     VTV  QDV ++   V  V +  F D        
Sbjct: 72  KVVAFEIDQRLLPILKDTLSPY---ENVTVIHQDVLKA--DVKSVIEEQFQD-------- 118

Query: 190 GHAWDALKVEGGRFCSFSPCIEQVQRTCQALA 221
               + + V    +   +P I ++      L 
Sbjct: 119 --CDEIMVVANLPYYVTTPIIMKLLEEHLPLK 148


>3R0Q-C nrPDB
          Length = 376

 Score = 33.3 bits (74), Expect = 0.12,   Method: Composition-based stats.
 Identities = 18/71 (25%), Positives = 26/71 (36%), Gaps = 3/71 (4%)

Query: 102 RPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRT 161
             G  V + GTGSG    AI    A    ++ VE  +  A+ AR   + + +   V V  
Sbjct: 62  FEGKTVLDVGTGSG--ILAIWSAQAGARKVYAVEATK-MADHARALVKANNLDHIVEVIE 118

Query: 162 QDVCRSGFGVS 172
             V        
Sbjct: 119 GSVEDISLPEK 129


>1ZQ9-A nrPDB
          Length = 285

 Score = 33.3 bits (74), Expect = 0.14,   Method: Composition-based stats.
 Identities = 19/95 (20%), Positives = 34/95 (35%), Gaps = 6/95 (6%)

Query: 89  STDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEF 148
              I  I     LRP  VV E G G+G+++  ++        +   E   +   +  +  
Sbjct: 14  PLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLE---KAKKVVACELDPRLVAELHKRV 70

Query: 149 QEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183
           Q   V   + V   DV ++        D    ++P
Sbjct: 71  QGTPVASKLQVLVGDVLKTDLP---FFDTCVANLP 102


>1EIZ-A nrPDB
          Length = 180

 Score = 32.5 bits (72), Expect = 0.20,   Method: Composition-based stats.
 Identities = 22/120 (18%), Positives = 35/120 (29%), Gaps = 22/120 (18%)

Query: 102 RPGSVVCESGTGSGSVSHAIIRTIAPTGHLHT-------------VEFHQQRAEKAREEF 148
           +PG  V + G   G  S  ++  I   G +                     R E   +  
Sbjct: 21  KPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKAL 80

Query: 149 QEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDA---LKVEGGRFCS 205
            E      V V   D+        +++    +DIP     V  A +    +   GG F  
Sbjct: 81  LERVGDSKVQVVMSDMAP------NMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVV 134


>2NNW-B nrPDB
          Length = 234

 Score = 32.5 bits (72), Expect = 0.22,   Method: Composition-based stats.
 Identities = 30/160 (18%), Positives = 58/160 (36%), Gaps = 15/160 (9%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
           ++PG  V   G  SG+ +  +   +   G ++ +EF  +   +     +E    R +   
Sbjct: 78  IKPGKSVLYLGIASGTTASHVSDIVGWEGKIYGIEFSPRVLRELVPIVEER---RNIIPI 134

Query: 161 TQDVCRSGFGVSHVA--DAVFLDIPSPWEA---VGHAWDALKVEG-------GRFCSFSP 208
             D  +     + V   D +F D+  P +A   + +A   LK  G        R    + 
Sbjct: 135 LGDATKPEEYRALVTKVDVIFEDVAQPTQAKILIDNAKAYLKRGGYGMIAVKSRSIDVTK 194

Query: 209 CIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248
             EQV +  +   +  F  +  L + P   +     +  P
Sbjct: 195 EPEQVFKEVERELSEYFEVIERLNLEPYEKDHALFVVRKP 234


>4FZV-A nrPDB
          Length = 359

 Score = 32.5 bits (72), Expect = 0.23,   Method: Composition-based stats.
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 8/103 (7%)

Query: 88  YSTDIALI--TMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAR 145
           Y  D A +   + L L+PG +V +     G  + A+++T     +L   +    R  + +
Sbjct: 131 YLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQT-GCCRNLAANDLSPSRIARLQ 189

Query: 146 EEF-----QEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIP 183
           +       +E R G  V V + D  + G       D V +D+P
Sbjct: 190 KILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVP 232


>2YXD-A nrPDB
          Length = 183

 Score = 32.5 bits (72), Expect = 0.23,   Method: Composition-based stats.
 Identities = 13/100 (13%), Positives = 32/100 (32%), Gaps = 6/100 (6%)

Query: 81  PHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQR 140
                I      A+    L L    VV + G GSG ++  I +       ++ +++    
Sbjct: 13  REGVPITKEEIRAVSIGKLNLNKDDVVVDVGCGSGGMTVEIAKRCK---FVYAIDYLDGA 69

Query: 141 AEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL 180
            E  ++   +  +     ++ +             +  F+
Sbjct: 70  IEVTKQNLAKFNIKNCQIIKGR---AEDVLDKLEFNKAFI 106


>4KDC-A nrPDB
          Length = 246

 Score = 32.1 bits (71), Expect = 0.28,   Method: Composition-based stats.
 Identities = 23/118 (19%), Positives = 36/118 (30%), Gaps = 2/118 (1%)

Query: 87  LYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAP-TGHLHTVEFHQQRAEKAR 145
           +    +  I        G  V + G G G ++ ++ R  A  TG     E  Q     A 
Sbjct: 46  INPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHAL 105

Query: 146 EEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRF 203
           E   +    +  TV       +G         +   +P P   V      +K  G  F
Sbjct: 106 ESGIQVDYVQE-TVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVF 162


>5WWT-A nrPDB
          Length = 477

 Score = 31.3 bits (69), Expect = 0.44,   Method: Composition-based stats.
 Identities = 16/103 (15%), Positives = 35/103 (33%), Gaps = 11/103 (10%)

Query: 92  IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE---- 147
            AL++ +L  +PG  + +     G  +  I   +   G +  ++    + EK ++     
Sbjct: 223 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLL 282

Query: 148 ----FQEHRVGRWVTVR---TQDVCRSGFGVSHVADAVFLDIP 183
                +         V+    +D       +    D + LD P
Sbjct: 283 GLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325


>3DMF-A nrPDB
          Length = 381

 Score = 31.3 bits (69), Expect = 0.45,   Method: Composition-based stats.
 Identities = 29/136 (21%), Positives = 48/136 (35%), Gaps = 13/136 (9%)

Query: 104 GSVVCESGTGSGSVSHAIIR----TIAPTGHLHTVEFHQQRAEKA--REEFQEHRVGRWV 157
           G  V + G G G+++  + R     +     L +V   Q+  E    + +     V   +
Sbjct: 234 GRQVLDLGAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEAL 293

Query: 158 TVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTC 217
           T   +          HV  AV LD+      V  A   L+  G  F   +P ++      
Sbjct: 294 TEEARFDIIVTNPPFHVGGAVILDVAQ--AFVNVAAARLRPGGVFFLVSNPFLK-----Y 346

Query: 218 QALAARGFSELSTLEV 233
           + L    F    TL+V
Sbjct: 347 EPLLEEKFGAFQTLKV 362


>4F86-A nrPDB
          Length = 320

 Score = 31.3 bits (69), Expect = 0.49,   Method: Composition-based stats.
 Identities = 26/200 (13%), Positives = 57/200 (28%), Gaps = 31/200 (15%)

Query: 33  GAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDI 92
                  +G+       +G P            ++ L      + L+             
Sbjct: 72  DGLYHHHYGIGAVDHAALGDPGDGGYEARLIAELHRLESAQAEFLLD------------- 118

Query: 93  ALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR 152
                +  + PG  + ++G G G       +       +  V     +AE      +E  
Sbjct: 119 ----HLGPVGPGDTLVDAGCGRGGSMVMAHQRFGCK--VEGVTLSAAQAEFGNRRARELG 172

Query: 153 VGRWVTVRTQDVCRSGFGVSHVA------DAVFLDIPSPWEAVGHAWDALKVEG---GRF 203
           +   V  R  ++  + F    VA       ++++D+    +        L+V G      
Sbjct: 173 IDDHVRSRVCNMLDTPFEKGTVAASWNNESSMYVDL---HDVFAEHSRFLRVGGRYVTVT 229

Query: 204 CSFSPCIEQVQRTCQALAAR 223
             ++P   Q  +    + A 
Sbjct: 230 GCWNPRYGQPSKWVSQINAH 249


>4FS8-A nrPDB
          Length = 383

 Score = 31.0 bits (68), Expect = 0.55,   Method: Composition-based stats.
 Identities = 11/49 (22%), Positives = 22/49 (44%)

Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEH 151
            G+ V + G G+G   +   + +   G +  V+    + E AR+  + H
Sbjct: 83  EGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQLEVARKYVEYH 131


>5WP5-A nrPDB
          Length = 491

 Score = 31.0 bits (68), Expect = 0.56,   Method: Composition-based stats.
 Identities = 24/153 (15%), Positives = 47/153 (30%), Gaps = 7/153 (4%)

Query: 103 PGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWV--TVR 160
            G  V E G G G  +  + +     G +  ++F +   +K       ++  +++   V 
Sbjct: 53  EGKSVLELGAGIGRFTGELAQ---KAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVT 109

Query: 161 TQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALK--VEGGRFCSFSPCIEQVQRTCQ 218
           + D+      +  +     L   S  E    A   +     GG       C  Q   + +
Sbjct: 110 SPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKR 169

Query: 219 ALAARGFSELSTLEVLPQVYNVRTVSLPPPDLG 251
                 + E      + Q    R  S    +L 
Sbjct: 170 KSNPTHYREPRFYTKVFQECQTRDASGNSFELS 202


>5FUB-A nrPDB
          Length = 337

 Score = 31.0 bits (68), Expect = 0.61,   Method: Composition-based stats.
 Identities = 16/69 (23%), Positives = 25/69 (36%), Gaps = 2/69 (2%)

Query: 104 GSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQD 163
             VV + G G+G +S        P G ++ VE     AE   E  +++     VTV  + 
Sbjct: 45  EKVVLDLGCGTGVISLFCALLAKPAG-VYAVEA-SSMAEHTEELVKQNGCDGVVTVFQER 102

Query: 164 VCRSGFGVS 172
                    
Sbjct: 103 AENLTLPTK 111


>3CJR-A nrPDB
          Length = 254

 Score = 30.6 bits (67), Expect = 0.88,   Method: Composition-based stats.
 Identities = 25/129 (19%), Positives = 46/129 (35%), Gaps = 6/129 (4%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
           LRPG  V + GTGSG ++ A    +   G    V+       +A    + + V       
Sbjct: 118 LRPGDKVLDLGTGSGVLAIA-AEKLG--GKALGVDIDPMVLPQAEANAKRNGVRPRFLEG 174

Query: 161 TQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQAL 220
           + +          +   ++ ++     A+   +    V GGR        ++     +A+
Sbjct: 175 SLEAALPFGPFDLLVANLYAEL---HAALAPRYREALVPGGRALLTGILKDRAPLVREAM 231

Query: 221 AARGFSELS 229
           A  GF  L 
Sbjct: 232 AGAGFRPLE 240


>4DZR-A nrPDB
          Length = 215

 Score = 30.2 bits (66), Expect = 0.96,   Method: Composition-based stats.
 Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 2/54 (3%)

Query: 104 GSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHR-VGRW 156
           G+ V + GTGSG ++ +I     P   +  V+        AR   +    V  W
Sbjct: 31  GTRVIDVGTGSGCIAVSIALAC-PGVSVTAVDLSMDALAVARRNAERFGAVVDW 83


>3E23-A nrPDB
          Length = 211

 Score = 30.2 bits (66), Expect = 1.0,   Method: Composition-based stats.
 Identities = 28/143 (19%), Positives = 41/143 (28%), Gaps = 23/143 (16%)

Query: 75  LWTLNLPHRTQILY----STDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGH 130
             TL         Y         L   + EL  G+ + E G G+G         +   G 
Sbjct: 11  DDTLRFYRGNATAYAERQPRSATLTKFLGELPAGAKILELGCGAG----YQAEAMLAAG- 65

Query: 131 LHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAV-----FLDIPSP 185
              V+      E A E  +         +  Q             DAV      L +P  
Sbjct: 66  -FDVDATDGSPELAAEASRRLGRPVRTMLFHQ------LDAIDAYDAVWAHACLLHVPRD 118

Query: 186 W--EAVGHAWDALKVEGGRFCSF 206
              + +   W ALK  G  + S+
Sbjct: 119 ELADVLKLIWRALKPGGLFYASY 141


>6H1E-A nrPDB
          Length = 208

 Score = 29.8 bits (65), Expect = 1.3,   Method: Composition-based stats.
 Identities = 9/21 (42%), Positives = 11/21 (52%)

Query: 108 CESGTGSGSVSHAIIRTIAPT 128
            E G+GSG VS  +   I P 
Sbjct: 44  LEVGSGSGVVSAFLASMIGPQ 64


>4JJI-A nrPDB
          Length = 378

 Score = 29.8 bits (65), Expect = 1.5,   Method: Composition-based stats.
 Identities = 15/78 (19%), Positives = 28/78 (35%), Gaps = 4/78 (5%)

Query: 101 LRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVR 160
           + PGS V   G G+  ++ A     A    +  ++   ++ E A    ++  V  +V  +
Sbjct: 191 VEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETA----KKFGVNEFVNPK 246

Query: 161 TQDVCRSGFGVSHVADAV 178
             D       V      V
Sbjct: 247 DHDKPIQEVIVDLTDGGV 264


>1TPY-A nrPDB
          Length = 287

 Score = 29.0 bits (63), Expect = 2.1,   Method: Composition-based stats.
 Identities = 22/103 (21%), Positives = 35/103 (33%), Gaps = 9/103 (8%)

Query: 64  GWVYVLHPTPELWTLNLPHRTQILYSTDIALI---TMMLELRPGSVVCESGTGSGS-VSH 119
            +   L PT      +       L    IA I      L L+PG  + + G G G+ +  
Sbjct: 22  FFRLFLDPTQTYSCAHFEREDMTLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRR 81

Query: 120 AII-RTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRT 161
           AI    +   G   +    + +A   ++ F E    R   V  
Sbjct: 82  AIAQYDVNVVGLTLS----KNQAAHVQKSFDEMDTPRDRRVLL 120


>1VQ1-A nrPDB
          Length = 294

 Score = 29.0 bits (63), Expect = 2.6,   Method: Composition-based stats.
 Identities = 13/60 (21%), Positives = 25/60 (41%), Gaps = 2/60 (3%)

Query: 105 SVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDV 164
             V + GTGSG++  ++ +       +   +   +  E AR+  + H V     VR  + 
Sbjct: 135 KTVADIGTGSGAIGVSVAKF--SDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGEF 192


>3W53-A nrPDB
          Length = 506

 Score = 28.7 bits (62), Expect = 3.3,   Method: Composition-based stats.
 Identities = 20/98 (20%), Positives = 36/98 (36%), Gaps = 3/98 (3%)

Query: 189 VGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPP 248
           V   W+ + ++     S+    E +    Q L      E   LE++ Q  +   V+    
Sbjct: 280 VDALWNRMYLDPVLRGSYP---EDLLEDVQGLGLAEVIEAGDLEIISQPIDFLGVNHYHD 336

Query: 249 DLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATK 286
           D  +G   PAG       + +P       + Y+TF  +
Sbjct: 337 DNVSGHPLPAGQPQPVVPTDSPKSSPFVGSEYVTFPAR 374


>1F8F-A nrPDB
          Length = 371

 Score = 28.7 bits (62), Expect = 3.3,   Method: Composition-based stats.
 Identities = 10/55 (18%), Positives = 21/55 (38%)

Query: 92  IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE 146
                  L++ P S     G G+  +S  +   +     +  V+  + R E A++
Sbjct: 179 AGACINALKVTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQ 233


>5TNX-A nrPDB
          Length = 383

 Score = 28.3 bits (61), Expect = 4.0,   Method: Composition-based stats.
 Identities = 16/86 (18%), Positives = 28/86 (32%), Gaps = 11/86 (12%)

Query: 92  IALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKARE----- 146
              +   L +R GS     G G+  +S  +   IA    +  V+    R   A E     
Sbjct: 190 AGAVINSLAVRTGSSFASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATH 249

Query: 147 --EFQEHRVGRWVTVRTQDVCRSGFG 170
               +E  V   +    +++   G  
Sbjct: 250 AINSKEVDVVDAI----REITGGGVD 271


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.309    0.120    0.293 

Lambda     K      H
   0.267   0.0367    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,786,733
Number of Sequences: 36641
Number of extensions: 363166
Number of successful extensions: 1179
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 1039
Number of HSP's gapped (non-prelim): 131
length of query: 289
length of database: 10,336,785
effective HSP length: 96
effective length of query: 193
effective length of database: 6,819,249
effective search space: 1316115057
effective search space used: 1316115057
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 58 (27.1 bits)