BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96AZ1 (226 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4QPN-A nrPDB 468 e-133 4LEC-A nrPDB 164 4e-41 4MTL-A nrPDB 89 2e-18 4LG1-A nrPDB 89 2e-18 4PWY-A nrPDB 39 0.002 4KDR-A nrPDB 34 0.053 3CJR-A nrPDB 34 0.053 3R0Q-C nrPDB 32 0.16 4KDC-A nrPDB 32 0.18 3MGG-A nrPDB 32 0.21 2I6G-A nrPDB 32 0.29 1G6Q-1 nrPDB 31 0.35 5BP9-A nrPDB 31 0.42 5LV5-A nrPDB 31 0.49 5EGS-A nrPDB 30 0.59 4LWO-B nrPDB 30 0.63 5URB-A nrPDB 30 0.89 6GXV-A nrPDB 29 1.5 5WP5-A nrPDB 29 1.5 3L1R-A nrPDB 29 1.7 5DST-A nrPDB 29 1.8 1F3L-A nrPDB 28 2.2 5IS8-A nrPDB 28 2.2 3B3J-A nrPDB 28 2.3 3Q7E-A nrPDB 28 2.5 4IKP-A nrPDB 28 2.5 4DCM-A nrPDB 28 2.5 5FUB-A nrPDB 28 2.7 3X0D-A nrPDB 28 3.0 3DMF-A nrPDB 28 4.0 6CU3-A nrPDB 28 4.0 4RYL-A nrPDB 28 4.1 6OGN-A nrPDB 28 4.4 2VS1-A nrPDB 27 5.3 5EVJ-A nrPDB 27 5.3 1RLU-A nrPDB 27 6.0 1WY7-A nrPDB 27 7.3 >4QPN-A nrPDB Length = 227 Score = 468 bits (1205), Expect = e-133, Method: Compositional matrix adjust. Identities = 226/226 (100%), Positives = 226/226 (100%) Query: 1 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA 60 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA Sbjct: 2 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA 61 Query: 61 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV 120 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV Sbjct: 62 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV 121 Query: 121 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS 180 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS Sbjct: 122 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS 181 Query: 181 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA 226 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA Sbjct: 182 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA 227 >4LEC-A nrPDB Length = 212 Score = 164 bits (414), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 90/197 (45%), Positives = 125/197 (63%), Gaps = 6/197 (3%) Query: 31 SQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVG 90 + F F H + I Q++ LGVAA VWDAA+ L Y E V+ RG+ +ELGAGTG+VG Sbjct: 16 ATFSFANHTIQIRQDW-RHLGVAAVVWDAAIVLSTYLEMGAVELRGRSAVELGAGTGLVG 74 Query: 91 ILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQ--VRALSWGIDHHVF-PANYDLV 147 I+AAL G VTITD +ALE ++ NVQAN+P Q + V+ L+WG + F P +DL+ Sbjct: 75 IVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQTKTVVKELTWGQNLGSFSPGEFDLI 134 Query: 148 LGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQR 207 LGADI+YLE TF LL TL+HLC H I LA ++R E ++ F +L + F + Sbjct: 135 LGADIIYLEETFTDLLQTLEHLCSNHSVILLACRIRYER--DNNFLAMLERQFTVRKVHY 192 Query: 208 DEDENVNIYRARHREPR 224 D +++V+IY A+ R + Sbjct: 193 DPEKDVHIYEAQKRNQK 209 >4MTL-A nrPDB Length = 244 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 63/200 (31%), Positives = 102/200 (51%), Gaps = 14/200 (7%) Query: 26 SYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFE--SQNVDFRGKKVIELG 83 SY+++ + F G + I ++ S A VW A++LC Y E ++ ++F+ K++E+G Sbjct: 45 SYTQE-HYRFAGKEIVIQESIESY---GAVVWPGAMALCQYLEEHAEELNFQDAKILEIG 100 Query: 84 AGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVP--AGGQAQVRALSWGID-HHVF 140 AG G+V I+A++ G VT TDLP L +Q N+ N +V+ L WG D F Sbjct: 101 AGPGLVSIVASILGAQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNF 160 Query: 141 PAN---YDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLP 197 P + YD VL +D+VY LL T+ +L +P + A+K R T+ F Sbjct: 161 PKSAFYYDYVLASDVVYHHYFLDKLLTTMVYLSQPGTVLLWANKFR--FSTDYEFLDKFK 218 Query: 198 QHFQLELAQRDEDENVNIYR 217 Q F L + +V +++ Sbjct: 219 QVFDTTLLAEYPESSVKLFK 238 >4LG1-A nrPDB Length = 224 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 67/204 (32%), Positives = 97/204 (47%), Gaps = 18/204 (8%) Query: 37 GHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRG------KKVIELGAGTGIVG 90 G VL + Q S GV VWDAA+ L Y E+ G + V+ELG+GTG VG Sbjct: 20 GTVLRLQQY--SSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVG 77 Query: 91 ILAALQGGDVTITDLPLALEQIQGNVQANV-PAGGQAQVRALSWGIDHHVFPANYDLVLG 149 ++AA G DV +TDL + ++ N+ N G Q + L WG + FP+ D +L Sbjct: 78 LMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILM 137 Query: 150 ADIVYLEPTFPLLLGTLQHLCRPHGTI---YLASKMRKEHGTESFFQHLLPQHFQLE--- 203 AD +Y E + LL TL+ + I Y M K E + LL F E Sbjct: 138 ADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIP 197 Query: 204 LAQRDED---ENVNIYRARHREPR 224 L + DE+ E+++I R ++ + Sbjct: 198 LEKHDEEYRSEDIHIIYIRKKKSK 221 >4PWY-A nrPDB Length = 264 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 10/129 (7%) Query: 56 VWDAALSLCNYFESQNVDFRGKKVIELGAG-TGIVGILAALQG--GDVTITD-LPLALEQ 111 +W + L Y N FR V ELG G T + G++ A+ +V +TD A+ Sbjct: 68 IWPSEEVLAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRN 127 Query: 112 IQGNVQANVPAG----GQAQVRALSWGIDHHV--FPANYDLVLGADIVYLEPTFPLLLGT 165 +Q + N AG + L W + V ++D+V+ AD ++L+ L+ Sbjct: 128 VQDIITRNQKAGVFKTQKISSCFLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDA 187 Query: 166 LQHLCRPHG 174 ++ L +P G Sbjct: 188 IKRLLQPRG 196 >4KDR-A nrPDB Length = 223 Score = 33.9 bits (76), Expect = 0.053, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 18/154 (11%) Query: 52 VAARVWD-----AALSLCN-----YFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVT 101 VA+R WD L N Y + GKKV+++G G GI+ A +G T Sbjct: 29 VASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGA--T 86 Query: 102 ITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHV--FPANYDLVLGADIVYLEPTF 159 +T L + E +Q + +G QV + ++ H YD+V +++ P Sbjct: 87 VTGLDMGFEPLQVAKLHALESG--IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDP 144 Query: 160 PLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQ 193 ++ L +P G ++ ++ R +G + F + Sbjct: 145 QSVVRACAQLVKPGGDVFFSTLNR--NGVKKFIK 176 >3CJR-A nrPDB Length = 254 Score = 33.9 bits (76), Expect = 0.053, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 76 GKKVIELGAGTGIVGILAALQGGDVTITDL-PLALEQIQGNVQAN 119 G KV++LG G+G++ I A GG D+ P+ L Q + N + N Sbjct: 121 GDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRN 165 >3R0Q-C nrPDB Length = 376 Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust. Identities = 24/108 (22%), Positives = 45/108 (41%), Gaps = 7/108 (6%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 F GK V+++G G+GI+ I +A G V + + + V+AN V + Sbjct: 62 FEGKTVLDVGTGSGILAIWSAQAGARKVYAVEATKMADHARALVKAN---NLDHIVEVIE 118 Query: 133 WGIDHHVFPANYDLVLGADIVYL---EPTFPLLLGTLQHLCRPHGTIY 177 ++ P D+++ + Y E F ++ +P G +Y Sbjct: 119 GSVEDISLPEKVDVIISEWMGYFLLRESMFDSVISARDRWLKPTGVMY 166 >4KDC-A nrPDB Length = 246 Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust. Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 16/144 (11%) Query: 52 VAARVWD-----AALSLCN-----YFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVT 101 VA+R WD L N Y + GKKV+++G G GI+ A +G T Sbjct: 29 VASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGA--T 86 Query: 102 ITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHV--FPANYDLVLGADIVYLEPTF 159 +T L + E +Q + +G QV + ++ H YD+V +++ P Sbjct: 87 VTGLDMGFEPLQVAKLHALESG--IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDP 144 Query: 160 PLLLGTLQHLCRPHGTIYLASKMR 183 ++ L +P G ++ ++ R Sbjct: 145 QSVVRACAQLVKPGGDVFFSTLNR 168 >3MGG-A nrPDB Length = 276 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 5/140 (3%) Query: 53 AARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQI 112 A R+ + A +L V G KV+E G G G ++ A D IT + ++ E + Sbjct: 15 ALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESL 74 Query: 113 QGNVQANVPAGGQAQVRALSWGIDHHVFP-ANYDLVLGADIVYLEPTFPLLLGTLQHLCR 171 + + N G V+ L I F +++D + ++ + L +L+ + + Sbjct: 75 E-KARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLK 133 Query: 172 PHGTIYLASKMRKEHGTESF 191 P GTI + + +HG+ F Sbjct: 134 PGGTITV---IEGDHGSCYF 150 >2I6G-A nrPDB Length = 199 Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 5/107 (4%) Query: 78 KVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDH 137 + ++LG G G + A G DVT D A N++ A G ++ ++ Sbjct: 34 RTLDLGCGNGRNSLYLAANGYDVTAWDKNPA---SMANLERIKAAEGLDNLQTDLVDLNT 90 Query: 138 HVFPANYDLVLGADI-VYLEP-TFPLLLGTLQHLCRPHGTIYLASKM 182 F YD +L + ++LE T P L+ +Q +P G + + M Sbjct: 91 LTFDGEYDFILSTVVMMFLEAQTIPGLIANMQRCTKPGGYNLIVAAM 137 >1G6Q-1 nrPDB Length = 328 Score = 31.2 bits (69), Expect = 0.35, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Query: 70 QNVD-FRGKKVIELGAGTGIVGILAALQGGDVTI-TDLPLALEQIQGNVQAN 119 QN D F+ K V+++G GTGI+ + AA G I D+ +E + V+ N Sbjct: 32 QNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELN 83 >5BP9-A nrPDB Length = 281 Score = 31.2 bits (69), Expect = 0.42, Method: Compositional matrix adjust. Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 15/107 (14%) Query: 79 VIELGAGTGIVGILAALQGGDVTITDL-PLALEQIQGNVQANVPAGGQAQVRALSWGIDH 137 ++++GAG+G + G +V+ D+ PL++E ++ G R ++ + Sbjct: 105 ILDVGAGSGCHALALQESGKEVSAIDISPLSVEVMK--------LRGVKDARQVN--LFD 154 Query: 138 HVFPANYDLVL----GADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS 180 F A +D +L G+ I+ PL ++ L RP G I + S Sbjct: 155 ERFAATFDTILMLMNGSGIIGRLENMPLFFRKMKQLLRPDGCILMDS 201 >5LV5-A nrPDB Length = 403 Score = 30.8 bits (68), Expect = 0.49, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 17/25 (68%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG 98 RGK V+++GAGTGI+ I A G Sbjct: 109 LRGKTVLDVGAGTGILSIFCAQAGA 133 >5EGS-A nrPDB Length = 376 Score = 30.4 bits (67), Expect = 0.59, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 17/25 (68%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG 98 RGK V+++GAGTGI+ I A G Sbjct: 82 LRGKTVLDVGAGTGILSIFCAQAGA 106 >4LWO-B nrPDB Length = 368 Score = 30.4 bits (67), Expect = 0.63, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 32/74 (43%), Gaps = 16/74 (21%) Query: 70 QNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQ---------------- 113 Q+ GK V+++G+GTGI+ + AA G + +L + Q Sbjct: 49 QSASIEGKVVVDVGSGTGILSMWAARAGAKHVFSIEASSLSEFQIGVVEDNDLSTKITVL 108 Query: 114 GNVQANVPAGGQAQ 127 G+ N+ AGG A Sbjct: 109 GDTVENIIAGGVAN 122 >5URB-A nrPDB Length = 567 Score = 30.0 bits (66), Expect = 0.89, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 16/83 (19%) Query: 148 LGADIVYLEPTF-PLLLGTLQHLCRPHGTI---YLA---SKMRKEHGT----ESFFQHLL 196 +G DIVY F P +L + P G +L KM K GT E++ QHL Sbjct: 312 IGKDIVYFHALFWPAMLEGANYRT-PTGLFVNGFLTVNGQKMSKSRGTFIKAETYLQHLN 370 Query: 197 PQ----HFQLELAQRDEDENVNI 215 P+ +F +L+ + ED ++N+ Sbjct: 371 PEYLRYYFASKLSDKVEDSDLNL 393 >6GXV-A nrPDB Length = 484 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 2/33 (6%) Query: 125 QAQVRALSWGIDHHVFPANYDLVLGADIVYLEP 157 Q Q +A W +D NYD ++GADI Y P Sbjct: 179 QIQGKAWDWEVDSE--NGNYDYLMGADIDYDHP 209 >5WP5-A nrPDB Length = 491 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 6/51 (11%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGG 124 + GK V+ELGAG G A + G+V +AL+ I+ +Q N G Sbjct: 52 YEGKSVLELGAGIGRFTGELAQKAGEV------IALDFIESAIQKNESVNG 96 >3L1R-A nrPDB Length = 478 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 18/114 (15%) Query: 76 GKKVIELGAGTGIVGILAALQGGDVTITDLPL--ALEQIQGNVQANVPAGGQAQVRALSW 133 G +VI +GAG + GI AA + + ITDL + A + I G + AG ++ A +W Sbjct: 4 GPRVIVVGAG--MSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA-NW 60 Query: 134 GIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHG 187 V G + + P +P++ TL+ YLA + KE G Sbjct: 61 -------------VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDG 101 >5DST-A nrPDB Length = 332 Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 18/25 (72%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG 98 F+ K V+++G+GTGI+ + AA G Sbjct: 48 FKDKVVLDVGSGTGILSMFAAKAGA 72 >1F3L-A nrPDB Length = 321 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVTI 102 F+ K V+++G GTGI+ + AA G I Sbjct: 44 FKDKVVLDVGCGTGILSMFAAKAGAKKVI 72 >5IS8-A nrPDB Length = 381 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 71 NVDFRGKKVIELGAGTGIVGILAALQGG 98 + DF+ K V+++G G+GI+ AA G Sbjct: 55 HTDFKDKIVLDVGCGSGILSFFAAQAGA 82 >3B3J-A nrPDB Length = 480 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 71 NVDFRGKKVIELGAGTGIVGILAALQGG 98 + DF+ K V+++G G+GI+ AA G Sbjct: 154 HTDFKDKIVLDVGCGSGILSFFAAQAGA 181 >3Q7E-A nrPDB Length = 349 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVTI 102 F+ K V+++G+GTGI+ + AA G I Sbjct: 65 FKDKVVLDVGSGTGILCMFAAKAGARKVI 93 >4IKP-A nrPDB Length = 341 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 71 NVDFRGKKVIELGAGTGIVGILAALQGG 98 + DF+ K V+++G G+GI+ AA G Sbjct: 41 HTDFKDKIVLDVGCGSGILSFFAAQAGA 68 >4DCM-A nrPDB Length = 375 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 27/47 (57%), Gaps = 3/47 (6%) Query: 78 KVIELGAGTGIVGIL---AALQGGDVTITDLPLALEQIQGNVQANVP 121 ++++LG G G++G+ Q V + + P+A+ + NV+ N+P Sbjct: 225 EIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMP 271 >5FUB-A nrPDB Length = 337 Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust. Identities = 11/27 (40%), Positives = 17/27 (62%) Query: 69 SQNVDFRGKKVIELGAGTGIVGILAAL 95 S + R K V++LG GTG++ + AL Sbjct: 38 SNSAALREKVVLDLGCGTGVISLFCAL 64 >3X0D-A nrPDB Length = 655 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 79 VIELGAGTGIVGILAALQGGD-VTITDLPLALEQIQGNVQANVPAGGQAQV 128 V+++G GTG++ ++AA +G D VT ++ + ++ +N P + V Sbjct: 76 VLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITV 126 >3DMF-A nrPDB Length = 381 Score = 27.7 bits (60), Expect = 4.0, Method: Compositional matrix adjust. Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 22/161 (13%) Query: 34 CFCGHVLTITQNFGSRLGV--AARVWDAALSLCNYFESQ--NVDFRGKKVIELGAGTGIV 89 F +L F GV A +V A+L L + + RG++V++LGAG G + Sbjct: 188 AFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDLGAGYGAL 247 Query: 90 GILAALQGGDVT-ITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVF-PANYDLV 147 + A G +V + D ++ +Q ++AN + +AL +D + A +D++ Sbjct: 248 TLPLARMGAEVVGVEDDLASVLSLQKGLEANA-----LKAQALHSDVDEALTEEARFDII 302 Query: 148 L--------GADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS 180 + GA I+ + F + RP G +L S Sbjct: 303 VTNPPFHVGGAVILDVAQAF---VNVAAARLRPGGVFFLVS 340 >6CU3-A nrPDB Length = 336 Score = 27.7 bits (60), Expect = 4.0, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVTI 102 F+ K V+++G GTGI+ + AA G I Sbjct: 50 FKDKVVLDIGCGTGILCLFAAKAGAKRVI 78 >4RYL-A nrPDB Length = 340 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 17/25 (68%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG 98 F+ K V+++G GTGI+ + AA G Sbjct: 63 FKDKVVLDVGCGTGILSMFAAKAGA 87 >6OGN-A nrPDB Length = 692 Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 2/30 (6%) Query: 72 VDFRGKK--VIELGAGTGIVGILAALQGGD 99 V RG+K V+++G GTG++ ++A G D Sbjct: 59 VKDRGQKALVLDIGTGTGLLSMMAVTAGAD 88 >2VS1-A nrPDB Length = 425 Score = 27.3 bits (59), Expect = 5.3, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 76 GKKVIELGAGTGIVGILAALQGGDVTITDL-PLALEQIQGNVQAN 119 G+K++++ +G G GI A +G +V D A+E + NV+ N Sbjct: 291 GEKILDMYSGVGTFGIYLAKRGFNVKGFDSNEFAIEMARRNVEIN 335 >5EVJ-A nrPDB Length = 387 Score = 27.3 bits (59), Expect = 5.3, Method: Compositional matrix adjust. Identities = 28/140 (20%), Positives = 60/140 (42%), Gaps = 22/140 (15%) Query: 74 FRGKKVIELGAGTG--------IVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQ 125 G +V++LGAG+G +VG ++ G D+T L +A+ + + G+ Sbjct: 82 IEGLRVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTPAQLEVAISHADAYARDKL-GYGK 140 Query: 126 AQVRALSWGIDH----HVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASK 181 + + + I++ + +++DLV+ ++ L P +L + P G + Sbjct: 141 SNMTFIQGEIEYLDRAGLEDSSFDLVISNCVINLSPDKARVLSEAYRVLAPGGEM----- 195 Query: 182 MRKEHGTESFFQHLLPQHFQ 201 H ++ + LPQ + Sbjct: 196 ----HFSDVYVDRRLPQSVR 211 >1RLU-A nrPDB Length = 382 Score = 27.3 bits (59), Expect = 6.0, Method: Compositional matrix adjust. Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 29/134 (21%) Query: 55 RVWDAALSLCNYFESQ---------------------NVDFRGKKVIELGAGTGIVGILA 93 ++ DAA+SL + F S NVDF K I GAGT ++GI + Sbjct: 171 QMGDAAVSLMDAFRSADEVLLNGVQGITDLITTPGLINVDFADVKGIMSGAGTALMGIGS 230 Query: 94 AL-QGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADI 152 A +G + ++ + ++ +++ G Q + +++ G D +F N L D Sbjct: 231 ARGEGRSLKAAEIAINSPLLEASME-----GAQGVLMSIAGGSDLGLFEINEAASLVQDA 285 Query: 153 VYLEPTFPLLLGTL 166 + P ++ GT+ Sbjct: 286 AH--PDANIIFGTV 297 >1WY7-A nrPDB Length = 207 Score = 26.9 bits (58), Expect = 7.3, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 17/30 (56%) Query: 73 DFRGKKVIELGAGTGIVGILAALQGGDVTI 102 D GK V +LGAGTG++ A L G I Sbjct: 47 DIEGKVVADLGAGTGVLSYGALLLGAKEVI 76 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4QPN-A nrPDB 367 e-102 4LEC-A nrPDB 260 3e-70 4LG1-A nrPDB 232 9e-62 4MTL-A nrPDB 231 2e-61 4PWY-A nrPDB 151 3e-37 Sequences not found previously or not previously below threshold: 4M36-A nrPDB 49 1e-06 5EKU-A nrPDB 49 2e-06 3MGG-A nrPDB 42 2e-04 3R0Q-C nrPDB 41 3e-04 2I6G-A nrPDB 40 0.001 3DMF-A nrPDB 39 0.001 6CU3-A nrPDB 37 0.005 1G6Q-1 nrPDB 37 0.008 4KDR-A nrPDB 37 0.009 4KDC-A nrPDB 37 0.009 3Q7E-A nrPDB 37 0.009 2IP2-A nrPDB 37 0.009 1F3L-A nrPDB 36 0.011 3X0D-A nrPDB 36 0.012 5WP4-A nrPDB 36 0.015 4QDJ-A nrPDB 35 0.027 5DST-A nrPDB 35 0.028 5FUB-A nrPDB 35 0.029 4RYL-A nrPDB 35 0.031 5WP5-A nrPDB 34 0.050 5EVJ-A nrPDB 34 0.053 3CJR-A nrPDB 34 0.059 6GXV-A nrPDB 34 0.077 5LV5-A nrPDB 34 0.077 5EGS-A nrPDB 33 0.084 6ACQ-A nrPDB 33 0.093 2ESR-A nrPDB 33 0.093 4LWO-B nrPDB 32 0.15 3EGE-A nrPDB 32 0.20 4FS8-A nrPDB 32 0.23 4KRI-A nrPDB 32 0.26 2AVN-A nrPDB 32 0.29 3BUS-A nrPDB 31 0.33 4BL3-A nrPDB 31 0.35 3CCF-A nrPDB 30 0.58 3M70-A nrPDB 30 0.69 1WY7-A nrPDB 30 0.84 1WS6-A nrPDB 30 0.96 2BJG-A nrPDB 30 1.00 1DUS-A nrPDB 30 1.1 6OGN-A nrPDB 29 1.3 4HGY-A nrPDB 29 1.3 4KUG-A nrPDB 29 1.9 6EC3-A nrPDB 29 2.3 2O57-A nrPDB 29 2.6 2QRJ-A nrPDB 28 3.1 2Q7V-A nrPDB 28 3.4 4NEC-A nrPDB 28 3.8 3E23-A nrPDB 28 4.0 2EFJ-A nrPDB 28 4.1 4INE-A nrPDB 28 4.4 2WHD-A nrPDB 27 5.1 4IE5-A nrPDB 27 6.2 6BPY-A nrPDB 27 8.8 2Q7X-A nrPDB 27 8.9 >4QPN-A nrPDB Length = 227 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 226/226 (100%), Positives = 226/226 (100%) Query: 1 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA 60 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA Sbjct: 2 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA 61 Query: 61 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV 120 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV Sbjct: 62 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV 121 Query: 121 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS 180 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS Sbjct: 122 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS 181 Query: 181 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA 226 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA Sbjct: 182 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA 227 >4LEC-A nrPDB Length = 212 Score = 260 bits (664), Expect = 3e-70, Method: Composition-based stats. Identities = 90/197 (45%), Positives = 125/197 (63%), Gaps = 6/197 (3%) Query: 31 SQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVG 90 + F F H + I Q++ LGVAA VWDAA+ L Y E V+ RG+ +ELGAGTG+VG Sbjct: 16 ATFSFANHTIQIRQDW-RHLGVAAVVWDAAIVLSTYLEMGAVELRGRSAVELGAGTGLVG 74 Query: 91 ILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQ--VRALSWGIDHHVF-PANYDLV 147 I+AAL G VTITD +ALE ++ NVQAN+P Q + V+ L+WG + F P +DL+ Sbjct: 75 IVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQTKTVVKELTWGQNLGSFSPGEFDLI 134 Query: 148 LGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQR 207 LGADI+YLE TF LL TL+HLC H I LA ++R E ++ F +L + F + Sbjct: 135 LGADIIYLEETFTDLLQTLEHLCSNHSVILLACRIRYER--DNNFLAMLERQFTVRKVHY 192 Query: 208 DEDENVNIYRARHREPR 224 D +++V+IY A+ R + Sbjct: 193 DPEKDVHIYEAQKRNQK 209 >4LG1-A nrPDB Length = 224 Score = 232 bits (592), Expect = 9e-62, Method: Composition-based stats. Identities = 67/204 (32%), Positives = 97/204 (47%), Gaps = 18/204 (8%) Query: 37 GHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRG------KKVIELGAGTGIVG 90 G VL + Q S GV VWDAA+ L Y E+ G + V+ELG+GTG VG Sbjct: 20 GTVLRLQQY--SSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVG 77 Query: 91 ILAALQGGDVTITDLPLALEQIQGNVQANV-PAGGQAQVRALSWGIDHHVFPANYDLVLG 149 ++AA G DV +TDL + ++ N+ N G Q + L WG + FP+ D +L Sbjct: 78 LMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILM 137 Query: 150 ADIVYLEPTFPLLLGTLQHLCRPHGTI---YLASKMRKEHGTESFFQHLLPQHFQLE--- 203 AD +Y E + LL TL+ + I Y M K E + LL F E Sbjct: 138 ADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIP 197 Query: 204 LAQRDED---ENVNIYRARHREPR 224 L + DE+ E+++I R ++ + Sbjct: 198 LEKHDEEYRSEDIHIIYIRKKKSK 221 >4MTL-A nrPDB Length = 244 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 63/200 (31%), Positives = 100/200 (50%), Gaps = 14/200 (7%) Query: 26 SYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQ--NVDFRGKKVIELG 83 SY+++ + F G + I ++ S A VW A++LC Y E ++F+ K++E+G Sbjct: 45 SYTQE-HYRFAGKEIVIQESIESY---GAVVWPGAMALCQYLEEHAEELNFQDAKILEIG 100 Query: 84 AGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVP--AGGQAQVRALSWGID-HHVF 140 AG G+V I+A++ G VT TDLP L +Q N+ N +V+ L WG D F Sbjct: 101 AGPGLVSIVASILGAQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNF 160 Query: 141 PAN---YDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLP 197 P + YD VL +D+VY LL T+ +L +P + A+K R T+ F Sbjct: 161 PKSAFYYDYVLASDVVYHHYFLDKLLTTMVYLSQPGTVLLWANKFR--FSTDYEFLDKFK 218 Query: 198 QHFQLELAQRDEDENVNIYR 217 Q F L + +V +++ Sbjct: 219 QVFDTTLLAEYPESSVKLFK 238 >4PWY-A nrPDB Length = 264 Score = 151 bits (381), Expect = 3e-37, Method: Composition-based stats. Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 12/180 (6%) Query: 56 VWDAALSLCNYFESQNVDFRGKKVIELGAG-TGIVGILAALQG--GDVTITD-LPLALEQ 111 +W + L Y N FR V ELG G T + G++ A+ +V +TD A+ Sbjct: 68 IWPSEEVLAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRN 127 Query: 112 IQGNVQANVPAG----GQAQVRALSWGIDHHV--FPANYDLVLGADIVYLEPTFPLLLGT 165 +Q + N AG + L W + V ++D+V+ AD ++L+ L+ Sbjct: 128 VQDIITRNQKAGVFKTQKISSCFLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDA 187 Query: 166 LQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRP 225 ++ L +P G + + R T + F +L + + DE+++ + ++ ++ P Sbjct: 188 IKRLLQPRGKAMVFAPRRGN--TLNQFCNLAEKAGFCIQRHENYDEHISNFHSKLKKENP 245 >4M36-A nrPDB Length = 343 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 58/151 (38%), Gaps = 9/151 (5%) Query: 79 VIELGAGTGIVGILAALQGGD--VTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGID 136 V+E+GAG+G++ ++AA G V + + + N++AN + +S + Sbjct: 64 VLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELK 123 Query: 137 HHVFPANYDLVLG---ADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQ 193 P D++L ++ E ++ L +P I + E Sbjct: 124 SKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDAL 183 Query: 194 HLLPQHF---QLELAQRDEDEN-VNIYRARH 220 H + L+L ++ V+I A+H Sbjct: 184 HRISSVSGWRDLDLKHMMTLQDTVSIVFAKH 214 >5EKU-A nrPDB Length = 390 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 58/151 (38%), Gaps = 9/151 (5%) Query: 79 VIELGAGTGIVGILAALQGGD--VTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGID 136 V+E+GAG+G++ ++AA G V + + + N++AN + +S + Sbjct: 99 VLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELK 158 Query: 137 HHVFPANYDLVLG---ADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQ 193 P D++L ++ E ++ L +P I + E Sbjct: 159 PKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDAL 218 Query: 194 HLLPQHF---QLELAQRDEDEN-VNIYRARH 220 H + L+L ++ V+I A+H Sbjct: 219 HRISSVSGWRDLDLKHMMTLQDTVSIVFAKH 249 >3MGG-A nrPDB Length = 276 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 9/142 (6%) Query: 40 LTITQNFGSRLGVAA-RVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGG 98 +++T+ A R+ + A +L V G KV+E G G G ++ A Sbjct: 1 MSLTEYVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNP 60 Query: 99 DVTITDL---PLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFP-ANYDLVLGADIVY 154 D IT + P +LE+ + N + N G V+ L I F +++D + ++ Sbjct: 61 DAEITSIDISPESLEKARENTEKN----GIKNVKFLQANIFSLPFEDSSFDHIFVCFVLE 116 Query: 155 LEPTFPLLLGTLQHLCRPHGTI 176 + L +L+ + +P GTI Sbjct: 117 HLQSPEEALKSLKKVLKPGGTI 138 >3R0Q-C nrPDB Length = 376 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 55/149 (36%), Gaps = 8/149 (5%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 F GK V+++G G+GI+ I +A G V + + + V+AN V + Sbjct: 62 FEGKTVLDVGTGSGILAIWSAQAGARKVYAVEATKMADHARALVKANNLDHI---VEVIE 118 Query: 133 WGIDHHVFPANYDLVLGADIVYL---EPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTE 189 ++ P D+++ + Y E F ++ +P G +Y + + Sbjct: 119 GSVEDISLPEKVDVIISEWMGYFLLRESMFDSVISARDRWLKPTGVMYPSHARMWLAPIK 178 Query: 190 SFFQHLLPQHFQLELAQ-RDEDENVNIYR 217 S F +A + + + Y Sbjct: 179 SNIADRKRNDFDGAMADWHNFSDEIKSYY 207 >2I6G-A nrPDB Length = 199 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 7/100 (7%) Query: 78 KVIELGAGTGIVGILAALQGGDVTITD-LPLALEQIQGNVQANVPAGGQAQVRALSWGID 136 + ++LG G G + A G DVT D P ++ ++ A Q + L + Sbjct: 34 RTLDLGCGNGRNSLYLAANGYDVTAWDKNPASMANLERIKAAEGLDNLQTDLVDL----N 89 Query: 137 HHVFPANYDLVLGADI-VYLE-PTFPLLLGTLQHLCRPHG 174 F YD +L + ++LE T P L+ +Q +P G Sbjct: 90 TLTFDGEYDFILSTVVMMFLEAQTIPGLIANMQRCTKPGG 129 >3DMF-A nrPDB Length = 381 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 43/202 (21%), Positives = 72/202 (35%), Gaps = 32/202 (15%) Query: 35 FCGHVLTITQNFGSRLGV--AARVWDAALSLCNYFES--QNVDFRGKKVIELGAGTGIVG 90 F +L F GV A +V A+L L + RG++V++LGAG G + Sbjct: 189 FSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDLGAGYGALT 248 Query: 91 ILAALQGGDVT-ITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVL- 148 + A G +V + D ++ +Q ++AN + A +D+++ Sbjct: 249 LPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDV----DEALTEEARFDIIVT 304 Query: 149 -------GADIVYLEPTFPLLLGTLQHLCRPHGTIYLASK--MRKEHGTESFFQHLLPQH 199 GA I+ + F + RP G +L S ++ E E F Sbjct: 305 NPPFHVGGAVILDVAQAFVNVAAAR---LRPGGVFFLVSNPFLKYEPLLEEKFGA----- 356 Query: 200 FQLELAQRDEDENVNIYRARHR 221 FQ + A R Sbjct: 357 FQTLKVAEY-----KVLFAEKR 373 >6CU3-A nrPDB Length = 336 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 46/113 (40%), Gaps = 13/113 (11%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGD-VTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 F+ K V+++G GTGI+ + AA G V D+ +++ + V N G + V L Sbjct: 50 FKDKVVLDIGCGTGILCLFAAKAGAKRVIGIDMSDIIDKARQIVSDN----GYSHVIELI 105 Query: 133 WGIDHHVFPANY-----DLVL---GADIVYLEPTFPLLLGTLQHLCRPHGTIY 177 G + + D+++ + E +L RP G ++ Sbjct: 106 KGKVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQTVLSARDRWLRPGGYLF 158 >1G6Q-1 nrPDB Length = 328 Score = 36.6 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 45/109 (41%), Gaps = 8/109 (7%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 F+ K V+++G GTGI+ + AA G V D+ +E + V+ N G ++ L Sbjct: 37 FKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELN---GFSDKITLLR 93 Query: 133 WGIDHHVFPAN-YDLVL---GADIVYLEPTFPLLLGTLQHLCRPHGTIY 177 ++ P D+++ + E +L H G I+ Sbjct: 94 GKLEDVHLPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIF 142 >4KDR-A nrPDB Length = 223 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 56/147 (38%), Gaps = 14/147 (9%) Query: 44 QNFGSRLGVAARVWDAA-----------LSLCNYFESQNVDFRGKKVIELGAGTGIVGIL 92 + VA+R WD L L E F GKKV+++G G GI+ Sbjct: 21 EEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLF-GKKVLDVGCGGGILAES 79 Query: 93 AALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADI 152 A +G T+T L + E +Q + +G Q + YD+V ++ Sbjct: 80 MAREGA--TVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEM 137 Query: 153 VYLEPTFPLLLGTLQHLCRPHGTIYLA 179 + P ++ L +P G ++ + Sbjct: 138 LEHVPDPQSVVRACAQLVKPGGDVFFS 164 >4KDC-A nrPDB Length = 246 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 56/147 (38%), Gaps = 14/147 (9%) Query: 44 QNFGSRLGVAARVWDAA-----------LSLCNYFESQNVDFRGKKVIELGAGTGIVGIL 92 + VA+R WD L L E F GKKV+++G G GI+ Sbjct: 21 EEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLF-GKKVLDVGCGGGILAES 79 Query: 93 AALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADI 152 A +G T+T L + E +Q + +G Q + YD+V ++ Sbjct: 80 MAREGA--TVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEM 137 Query: 153 VYLEPTFPLLLGTLQHLCRPHGTIYLA 179 + P ++ L +P G ++ + Sbjct: 138 LEHVPDPQSVVRACAQLVKPGGDVFFS 164 >3Q7E-A nrPDB Length = 349 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 45/131 (34%), Gaps = 6/131 (4%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 F+ K V+++G+GTGI+ + AA G V + + V+AN ++ Sbjct: 65 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKV 124 Query: 133 WGIDHHVFPANYDLVL---GADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTE 189 + + D+++ ++ E +L P G I+ E Sbjct: 125 --EEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIE 182 Query: 190 SFFQHLLPQHF 200 H+ Sbjct: 183 DRQYKDYKIHW 193 >2IP2-A nrPDB Length = 334 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 72 VDFRGKKVIELGAGTGIV--GILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVR 129 +DFRG+ +++G G+G + IL A + D +L + N+ ++ AG + Sbjct: 164 LDFRGRSFVDVGGGSGELTKAILQAEPSARGVMLDREGSLGVARDNLS-SLLAGERVS-- 220 Query: 130 ALSWGIDHHVFPANYDLVLGADIV 153 L G P+N D+ L + I+ Sbjct: 221 -LVGGDMLQEVPSNGDIYLLSRII 243 >1F3L-A nrPDB Length = 321 Score = 36.2 bits (82), Expect = 0.011, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 73 DFRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRAL 131 F+ K V+++G GTGI+ + AA G V D L Q ++ N + + + Sbjct: 43 IFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKL---EDTIVLI 99 Query: 132 SWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQH 168 I+ P V+ ++ + F +L ++ + Sbjct: 100 KGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLY 136 >3X0D-A nrPDB Length = 655 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 52/139 (37%), Gaps = 16/139 (11%) Query: 68 ESQNVDFRGKKVIELGAGTGIVGILAALQGGD-VTITDLPLALEQIQGNVQANVPAGGQA 126 + V+++G GTG++ ++AA +G D VT ++ + ++ +N P + Sbjct: 65 KKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKI 124 Query: 127 QVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLG---------TLQHLCRPHGTIY 177 V + D + ADI+ E L+G L+ L +P + Sbjct: 125 TVISER-STDVSQIGGS-----RADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVV 178 Query: 178 LASKMRKEHGTESFFQHLL 196 ++ ES + Sbjct: 179 PSTGNVYIVPVESHLLKMF 197 >5WP4-A nrPDB Length = 491 Score = 35.9 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 52/155 (33%), Gaps = 7/155 (4%) Query: 46 FGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGI-LAALQGGDVTITD 104 + G + + E N+ G+KV+++G G G +A V D Sbjct: 254 YERVFGQGFVSTGGLETTKEFVEKMNLK-PGQKVLDVGCGIGGGDFYMAEKFDVHVVGID 312 Query: 105 LPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPAN-YDLVLGADIVYLEPTFPLLL 163 L ++ I ++ G V +P N +D++ D + P L Sbjct: 313 L--SVNMISFALER--AIGLSCSVEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALF 368 Query: 164 GTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQ 198 T +P G + ++ R + F + Q Sbjct: 369 RTFFKWLKPGGKVLISDYCRSPKTPSAEFSEYIKQ 403 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 10/79 (12%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPA-GGQAQVRALS 132 + GK V+ELGAG G A + G++ AL+ I ++ N G V+ + Sbjct: 52 YEGKSVLELGAGIGRFTGELAQKAGELI------ALDFIDNVIKKNESINGHYKNVKFMC 105 Query: 133 WGI---DHHVFPANYDLVL 148 + D + + DL+ Sbjct: 106 ADVTSPDLKITDGSLDLIF 124 >4QDJ-A nrPDB Length = 238 Score = 35.1 bits (79), Expect = 0.027, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 34/87 (39%), Gaps = 5/87 (5%) Query: 73 DFRGKKVIELGAGTGIVGILAALQGGDVTITDL-PLALEQIQGNVQANVPAGGQAQVRAL 131 + G V + G G G + I A G V +D+ + + Q Q + G Q + Sbjct: 60 NLPGLLVCDAGCGVGSLSIPLAQAGALVYGSDISEKMVGEAQQKAQEVLAYGNQPT--FM 117 Query: 132 SWGIDHHVFPANYDLVLGADIVYLEPT 158 + D YD V+ D++ PT Sbjct: 118 T--QDLAQLGGKYDTVICLDVLIHYPT 142 >5DST-A nrPDB Length = 332 Score = 35.1 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 50/137 (36%), Gaps = 18/137 (13%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVT-------ITDLPLALEQIQGNVQANVPAGGQA 126 F+ K V+++G+GTGI+ + AA G I+D + I+ N N+ + Sbjct: 48 FKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKI--IKANHLDNIITIFKG 105 Query: 127 QVRALSWGIDHHVFPANYDLVL---GADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMR 183 +V + ++ D+++ ++ E ++ +P G ++ Sbjct: 106 KVEEVELPVE------KVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAAL 159 Query: 184 KEHGTESFFQHLLPQHF 200 E H+ Sbjct: 160 YVVAIEDRQYKDFKIHW 176 >5FUB-A nrPDB Length = 337 Score = 35.1 bits (79), Expect = 0.029, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 44/125 (35%), Gaps = 8/125 (6%) Query: 58 DAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQG--GDVTITDLPLALEQIQGN 115 + S + R K V++LG GTG++ + AL V + E + Sbjct: 27 PRTETYRQVILSNSAALREKVVLDLGCGTGVISLFCALLAKPAGVYAVEASSMAEHTEEL 86 Query: 116 VQANVPAGGQAQVRALSWGIDHHVFPANYDLVL---GADIVYLEPTFPLLLGTLQHLCRP 172 V+ N G + + ++ P D+++ + + E +L + Sbjct: 87 VKQNGCDGVVTVFQERA---ENLTLPTKVDVLVSEWMGNCLLFEYMLESVLLARDRWLKK 143 Query: 173 HGTIY 177 G ++ Sbjct: 144 GGMMW 148 >4RYL-A nrPDB Length = 340 Score = 34.7 bits (78), Expect = 0.031, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 73 DFRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVP 121 F+ K V+++G GTGI+ + AA G V D L Q ++ N Sbjct: 62 IFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKL 111 >5WP5-A nrPDB Length = 491 Score = 33.9 bits (76), Expect = 0.050, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 46/124 (37%), Gaps = 4/124 (3%) Query: 76 GKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGI 135 G+KV+++G G G A + DV + + L++ I ++ G + V Sbjct: 283 GQKVLDVGCGIGGGDFYMA-ENFDVHVVGIDLSVNMISFALER--AIGLKCSVEFEVADC 339 Query: 136 DHHVFPAN-YDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQH 194 +P N +D++ D + P L T +P G + + R F Sbjct: 340 TTKTYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAETPSPEFAE 399 Query: 195 LLPQ 198 + Q Sbjct: 400 YIKQ 403 Score = 33.2 bits (74), Expect = 0.084, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 12/110 (10%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPA-GGQAQVRALS 132 + GK V+ELGAG G A + G+V AL+ I+ +Q N G ++ + Sbjct: 52 YEGKSVLELGAGIGRFTGELAQKAGEVI------ALDFIESAIQKNESVNGHYKNIKFMC 105 Query: 133 WGI---DHHVFPANYDLVLGADIVYL--EPTFPLLLGTLQHLCRPHGTIY 177 + D + + DL+ ++ + L+ + +P G I+ Sbjct: 106 ADVTSPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIF 155 >5EVJ-A nrPDB Length = 387 Score = 33.9 bits (76), Expect = 0.053, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 50/112 (44%), Gaps = 13/112 (11%) Query: 75 RGKKVIELGAGTG--------IVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQA 126 G +V++LGAG+G +VG ++ G D+T L +A+ + G++ Sbjct: 83 EGLRVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTPAQLEVAISH-ADAYARDKLGYGKS 141 Query: 127 QVRALSWGIDH----HVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHG 174 + + I++ + +++DLV+ ++ L P +L + P G Sbjct: 142 NMTFIQGEIEYLDRAGLEDSSFDLVISNCVINLSPDKARVLSEAYRVLAPGG 193 >3CJR-A nrPDB Length = 254 Score = 33.9 bits (76), Expect = 0.059, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 6/87 (6%) Query: 76 GKKVIELGAGTGIVGILAALQGGDVTITDL-PLALEQIQGNVQANVPAGGQAQVRALSWG 134 G KV++LG G+G++ I A GG D+ P+ L Q + N + N + R L Sbjct: 121 GDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRN-----GVRPRFLEGS 175 Query: 135 IDHHVFPANYDLVLGADIVYLEPTFPL 161 ++ + +DL++ L Sbjct: 176 LEAALPFGPFDLLVANLYAELHAALAP 202 >6GXV-A nrPDB Length = 484 Score = 33.5 bits (75), Expect = 0.077, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 21/41 (51%) Query: 117 QANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEP 157 Q+ +G Q++ +W + NYD ++GADI Y P Sbjct: 169 QSRQLSGKIYQIQGKAWDWEVDSENGNYDYLMGADIDYDHP 209 >5LV5-A nrPDB Length = 403 Score = 33.5 bits (75), Expect = 0.077, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 7/111 (6%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 RGK V+++GAGTGI+ I A G V + +Q + V+ N G + +V L Sbjct: 109 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLN---GLEDRVHVLP 165 Query: 133 WGIDHHVFPANYDLVLGADIVY---LEPTFPLLLGTLQHLCRPHGTIYLAS 180 ++ P D ++ + Y E +L + G + AS Sbjct: 166 GPVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPAS 216 >5EGS-A nrPDB Length = 376 Score = 33.2 bits (74), Expect = 0.084, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 7/111 (6%) Query: 74 FRGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAGGQAQVRALS 132 RGK V+++GAGTGI+ I A G V + +Q + V+ N G + +V L Sbjct: 82 LRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFN---GLEDRVHVLP 138 Query: 133 WGIDHHVFPANYDLVLGADIVY---LEPTFPLLLGTLQHLCRPHGTIYLAS 180 ++ P D ++ + Y E +L + G + AS Sbjct: 139 GPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPAS 189 >6ACQ-A nrPDB Length = 302 Score = 33.2 bits (74), Expect = 0.093, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 41/114 (35%), Gaps = 17/114 (14%) Query: 77 KKVIELGAGTGIVGILAALQGG--DVTITDLPL-----ALEQIQGNVQANVPAGGQAQVR 129 KKV +GAGT GI A +V + D+ L+ I N+ V G + Sbjct: 22 KKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEAT 81 Query: 130 ALSWGIDHHVFPANYDLVLGADI-VYLEPTFPLL------LGTLQHLCRPHGTI 176 + DL + AD + +E + L ++C+P + Sbjct: 82 KV---EILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETIL 132 >2ESR-A nrPDB Length = 177 Score = 33.2 bits (74), Expect = 0.093, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 37/95 (38%), Gaps = 4/95 (4%) Query: 74 FRGKKVIELGAGTGIVGILAALQG--GDVTITDLPLALEQIQGNVQANVPAGGQAQVRAL 131 F G +V++L AG+G + I A +G V + A IQ N+ A + + + Sbjct: 30 FNGGRVLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIM-TKAENRFTLLKM 88 Query: 132 SWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTL 166 +DLV D Y + T + L Sbjct: 89 EAERAIDCLTGRFDLVFL-DPPYAKETIVATIEAL 122 >4LWO-B nrPDB Length = 368 Score = 32.4 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 13/110 (11%) Query: 19 EVGLFADSYSEKSQFCFCGHVLTITQNFGSR--LGVAARVWDAALSLCNYFES--QNVDF 74 E G FA+ Y S Q + S L V + + A + Y +S Q+ Sbjct: 2 ESGGFAEDYDPNSSLH--------HQYYESYSDLAVHRLMLEDAQRMSFYRKSIEQSASI 53 Query: 75 RGKKVIELGAGTGIVGILAALQGG-DVTITDLPLALEQIQGNVQANVPAG 123 GK V+++G+GTGI+ + AA G V + E G V+ N + Sbjct: 54 EGKVVVDVGSGTGILSMWAARAGAKHVFSIEASSLSEFQIGVVEDNDLST 103 >3EGE-A nrPDB Length = 261 Score = 32.0 bits (71), Expect = 0.20, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 48/152 (31%), Gaps = 19/152 (12%) Query: 75 RGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALS-W 133 +G + ++GAGTG + A QG V ++ ++ A QV + + Sbjct: 34 KGSVIADIGAGTGGYSVALANQGLFVYA---------VEPSIVMRQQAVVHPQVEWFTGY 84 Query: 134 GIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMR---------K 184 + + + D V+ ++ +Q + R + L +R Sbjct: 85 AENLALPDKSVDGVISILAIHHFSHLEKSFQEMQRIIRDGTIVLLTFDIRLAQRIWLYDY 144 Query: 185 EHGTESFFQHLLPQHFQLELAQRDEDENVNIY 216 LP Q+ L Q + V Sbjct: 145 FPFLWEDALRFLPLDEQINLLQENTKRRVEAI 176 >4FS8-A nrPDB Length = 383 Score = 32.0 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 54/137 (39%), Gaps = 15/137 (10%) Query: 73 DFRGKKVIELGAGTG--------IVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGG 124 G V++LG GTG +VG + G D+ L +A + ++ + + + Sbjct: 81 SLEGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQLEVARKYVEYHAEKFFGSPS 140 Query: 125 QAQVRALSWGIDH------HVFP-ANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIY 177 ++ VR L I++ P ++ D+V+ + L L + + R G +Y Sbjct: 141 RSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCVCNLSTNKLALFKEIHRVLRDGGELY 200 Query: 178 LASKMRKEHGTESFFQH 194 + +E+ Q Sbjct: 201 FSDVYADRRLSEAAQQD 217 >4KRI-A nrPDB Length = 433 Score = 31.6 bits (70), Expect = 0.26, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 16/143 (11%) Query: 76 GKKVIELGAGTGIVGILAA------LQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVR 129 G++++++G G G AA + G D++ L +ALE+ V A V Sbjct: 223 GQRMLDIGVGIGGGARQAASEFGLQVHGVDLSTNMLAVALER----VHKEKDARVTYAVC 278 Query: 130 ALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGT- 188 ++ P ++D V D + L + +P G + + + HGT Sbjct: 279 D---ACEYEFEPNSFDYVFSRDCIQHIKDTDKLFSRIYRALKPGGKVLI-TMYGVGHGTL 334 Query: 189 -ESFFQHLLPQHFQLELAQRDED 210 ESF +++ + + L+ ++ E+ Sbjct: 335 SESFKEYVSQRQYYLKNLEQIEE 357 >2AVN-A nrPDB Length = 260 Score = 31.6 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 40/103 (38%), Gaps = 13/103 (12%) Query: 78 KVIELGAGTGIVGILAALQGGDVTITD-LPLALEQIQGNVQANVPAGGQAQVRALSWGID 136 +V++LG GTG + +G +V + D LE + NV + +A + Sbjct: 57 RVLDLGGGTGKWSLFLQERGFEVVLVDPSKEMLEVAREKGVKNV-----VEAKA-----E 106 Query: 137 HHVFP-ANYDLVLG-ADIVYLEPTFPLLLGTLQHLCRPHGTIY 177 FP ++ VL D++ ++ + P G + Sbjct: 107 DLPFPSGAFEAVLALGDVLSYVENKDKAFSEIRRVLVPDGLLI 149 >3BUS-A nrPDB Length = 273 Score = 31.2 bits (69), Expect = 0.33, Method: Composition-based stats. Identities = 38/180 (21%), Positives = 65/180 (36%), Gaps = 16/180 (8%) Query: 1 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA 60 MA P P+ E ++ FA + E F + G V DA Sbjct: 1 MAAPTPE---EVRQMYDDFTDPFARIWGENLHFG----------YWED-AGADVSVDDAT 46 Query: 61 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV 120 L + + G +V+++G G G + A DV +T + ++ Q+ Sbjct: 47 DRLTDEMIALLDVRSGDRVLDVGCGIGKPAVRLAT-ARDVRVTGISISRPQVNQANARAT 105 Query: 121 PAGGQAQVRALSWGIDHHVFP-ANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLA 179 AG +V F A++D V + ++ P L + + RP GT+ +A Sbjct: 106 AAGLANRVTFSYADAMDLPFEDASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIA 165 >4BL3-A nrPDB Length = 640 Score = 31.2 bits (69), Expect = 0.35, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 30/73 (41%) Query: 12 SESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQN 71 ++ + +GL + +K+ + G +++G V + + L ES + Sbjct: 379 TQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSD 438 Query: 72 VDFRGKKVIELGA 84 F + +ELG+ Sbjct: 439 NIFFARVALELGS 451 >3CCF-A nrPDB Length = 279 Score = 30.5 bits (67), Expect = 0.58, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 17/71 (23%) Query: 48 SRLGVAARVWDAALSLCNYFESQNVDFR-------------GKKVIELGAGTGIVGILAA 94 + LG A WDA L Y + + ++ G+ +++LG GTG + A Sbjct: 21 TNLGTAKNFWDATL----YQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEKIA 76 Query: 95 LQGGDVTITDL 105 G +V TD Sbjct: 77 QSGAEVLGTDN 87 >3M70-A nrPDB Length = 286 Score = 30.5 bits (67), Expect = 0.69, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 38/94 (40%), Gaps = 10/94 (10%) Query: 78 KVIELGAGTGIVGILAALQGGDVTITD-LPLALEQIQGNVQANVPAGGQAQVRALSWGID 136 KV++LG G G + +L G DVT D ++ + + + I+ Sbjct: 123 KVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNE-----TKEKENLNISTALYDIN 177 Query: 137 HHVFPANYDLVLGADIVYL---EPTFPLLLGTLQ 167 NYD ++ + +V++ P ++ ++ Sbjct: 178 AANIQENYDFIV-STVVFMFLNRERVPSIIKNMK 210 >1WY7-A nrPDB Length = 207 Score = 30.1 bits (66), Expect = 0.84, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 9/79 (11%) Query: 73 DFRGKKVIELGAGTGIVGILAALQGGD--VTITDLPLALEQIQGNVQANVPAGGQAQVRA 130 D GK V +LGAGTG++ A L G + + A++ + N+ G+ + + Sbjct: 47 DIEGKVVADLGAGTGVLSYGALLLGAKEVICVEVDKEAVDVLIENL-------GEFKGKF 99 Query: 131 LSWGIDHHVFPANYDLVLG 149 + D F + D+V+ Sbjct: 100 KVFIGDVSEFNSRVDIVIM 118 >1WS6-A nrPDB Length = 171 Score = 29.7 bits (65), Expect = 0.96, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 84 AGTGIVGILAALQGGD-VTITDLPLALEQIQGNVQA 118 AG+G VG+ AA +G + V + P A+ ++ NV+ Sbjct: 50 AGSGAVGLEAASEGWEAVLVEKDPEAVRLLKENVRR 85 >2BJG-A nrPDB Length = 329 Score = 29.7 bits (65), Expect = 1.00, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 39/111 (35%), Gaps = 27/111 (24%) Query: 11 ESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQ 70 E +VF +G+ +S + F HV + Q G R Y + Sbjct: 161 EKLNVFDNNIGVLTNSPT------FDWHVANLNQYVGLR----------------YNQVP 198 Query: 71 NVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVP 121 + + LG GTG+VG+ GD T + + ++ + N Sbjct: 199 EFKLGDQSLTALGQGTGLVGL-----PGDFTPASRFIRVAFLRDAMIKNDK 244 >1DUS-A nrPDB Length = 194 Score = 29.7 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 75 RGKKVIELGAGTGIVGILAALQGGDVTITD-LPLALEQIQGNVQANVPAGGQAQV 128 + +++LG G G++GI A + T+ D A++ + N++ N +V Sbjct: 52 KDDDILDLGCGYGVIGIALADEVKSTTMADINRRAIKLAKENIKLNNLDNYDIRV 106 >6OGN-A nrPDB Length = 692 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 16/26 (61%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGD 99 + V+++G GTG++ ++A G D Sbjct: 63 GQKALVLDIGTGTGLLSMMAVTAGAD 88 >4HGY-A nrPDB Length = 276 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 49/142 (34%), Gaps = 11/142 (7%) Query: 77 KKVIELGAGTGIVGILAALQGGDVT-ITDLPLALEQIQGNVQANVPAGGQAQVRALSWGI 135 + V+ELG GTG V A G +V + L++++ A+ G V L Sbjct: 64 RPVLELGVGTGRVAFPLADLGVEVHGVESSEPMLDKLREKAAAH--PNGNLVVPVLGNFA 121 Query: 136 DHHVFPANYDLVLGA----DIVYLEPTFPLLLGTLQHLCRPHGTIYLAS--KMRKEHGTE 189 + Y +V A + + + + L P GT + + T Sbjct: 122 KLDLGEQRYSVVFAAFNTLFCLLGQDEQIDCMRQARELLEPGGTFVVQCLNPAGQRLATG 181 Query: 190 SFF--QHLLPQHFQLELAQRDE 209 + F L LE ++ D Sbjct: 182 NTFGTVELEDTAVHLEASKHDP 203 >4KUG-A nrPDB Length = 290 Score = 28.9 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 40/113 (35%), Gaps = 15/113 (13%) Query: 77 KKVIELGAGTGIVGILAALQ--GGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWG 134 KKV LGAGT GI+ A G +V + D+ E + + + + + Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKE--EFVDRGIATITKSLSKLVAKEKITE 59 Query: 135 IDHHV----FPANYDLVLGADI-VYLEPTFPLL------LGTLQHLCRPHGTI 176 D D+ L AD + +E + L +C+P + Sbjct: 60 ADKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETIL 112 >6EC3-A nrPDB Length = 471 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 48/146 (32%), Gaps = 12/146 (8%) Query: 66 YFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLP-----LALEQIQGNVQAN- 119 Y SQ+ R + E G + L AL+G D L LE + N++ Sbjct: 56 YLLSQDPADRARAFYEAFPGATRILELGALEGADTLALARQPGTSILGLEGREENLRRAE 115 Query: 120 --VPAGGQAQVRALSWGIDHHVFP--ANYDLVLGADIVYLEPTFPLLLGTLQHLCR--PH 173 + G V ++ F +D VL A ++Y LL + Sbjct: 116 FVMEVHGATNVELRIADVETLDFATLGRFDAVLCAGLLYHVREPWALLKDAARVSAGIYL 175 Query: 174 GTIYLASKMRKEHGTESFFQHLLPQH 199 T Y S E +H+ +H Sbjct: 176 STHYWGSSDGLETLDGYSVKHVREEH 201 >2O57-A nrPDB Length = 297 Score = 28.5 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 6/139 (4%) Query: 63 LCNYFESQNVDFRGKKVIELGAG-TGIVGILAALQGGDVTITDLPLALEQIQGNVQANVP 121 L + V R K ++LGAG G L G V+I L +A Q + N + N Sbjct: 70 LASELAMTGVLQRQAKGLDLGAGYGGAARFLVRKFG--VSIDCLNIAPVQNKRNEEYNNQ 127 Query: 122 AGGQAQVRALSWGI--DHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLA 179 AG A + +G + +YD + D P + + +P G + + Sbjct: 128 AG-LADNITVKYGSFLEIPCEDNSYDFIWSQDAFLHSPDKLKVFQECARVLKPRGVMAIT 186 Query: 180 SKMRKEHGTESFFQHLLPQ 198 M+++ +S Q +L + Sbjct: 187 DPMKEDGIDKSSIQPILDR 205 >2QRJ-A nrPDB Length = 394 Score = 28.2 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 16/53 (30%), Gaps = 5/53 (9%) Query: 124 GQAQVRALSWGIDHHVFPANYDLVLGAD----IVYLEPTFPLLLGTLQHLCRP 172 G L W I +D + AD +YL ++ L P Sbjct: 238 GIPDANILKWDIKETSRGGPFDEIPQADIFINCIYLSKPIAPF-TNMEKLNNP 289 >2Q7V-A nrPDB Length = 325 Score = 28.2 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 27/74 (36%), Gaps = 17/74 (22%) Query: 79 VIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHH 138 V+ +G G G+ AA+ G ++ L + GGQ W + Sbjct: 11 VVIIGGGP--AGLTAAIYTGRAQLSTL----------ILEKGMPGGQIA-----WSEEVE 53 Query: 139 VFPANYDLVLGADI 152 FP + + G ++ Sbjct: 54 NFPGFPEPIAGMEL 67 >4NEC-A nrPDB Length = 264 Score = 27.8 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 38/122 (31%), Gaps = 7/122 (5%) Query: 57 WDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDL-PLALEQIQGN 115 WD Y + V++ G GTG + A G VT DL P A+ + Sbjct: 41 WDIGAPQPAYVALEKAGLIQGAVLDAGCGTGEDALHLAGLGYAVTGLDLSPTAISVARDK 100 Query: 116 VQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADI--VYLEPTFPLLLGTLQHLCRPH 173 A AL D + +D V+ + + + L CRP Sbjct: 101 ADARGLGAVFEVADAL----DLTGWEERFDTVIDSGLAHTFEGDRLRAYATALHRACRPG 156 Query: 174 GT 175 Sbjct: 157 AV 158 >3E23-A nrPDB Length = 211 Score = 27.8 bits (60), Expect = 4.0, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 39/118 (33%), Gaps = 13/118 (11%) Query: 76 GKKVIELGAGTGIVGILAALQGGDVTITD-LPLALEQIQGNVQANVPAGGQAQVRALSWG 134 G K++ELG G G G DV TD P + + V Q+ A+ Sbjct: 44 GAKILELGCGAGYQAEAMLAAGFDVDATDGSPELAAEASRRLGRPVRTMLFHQLDAI--- 100 Query: 135 IDHHVFPANYDLVLGADIVYLEP--TFPLLLGTLQHLCRPHGTIYLASKMRKEHGTES 190 YD V + P +L + +P G Y + K + G + Sbjct: 101 -------DAYDAVWAHACLLHVPRDELADVLKLIWRALKPGGLFYASYKSGEGEGRDK 151 >2EFJ-A nrPDB Length = 384 Score = 27.8 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 18/59 (30%), Gaps = 2/59 (3%) Query: 152 IVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQRDED 210 ++ P L T + G IY + R + + + F L E+ Sbjct: 158 CLHWLSQVPSGLVTELGISVNKGCIYSSKASR--PPIQKAYLDQFTKDFTTFLRIHSEE 214 >4INE-A nrPDB Length = 454 Score = 27.8 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 36/104 (34%), Gaps = 5/104 (4%) Query: 76 GKKVIELGAGTGI-VGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWG 134 G+ ++++G G G +A G V DL + + ++V+ Sbjct: 242 GQTMLDIGVGIGGGARQVADEFGVHVHGIDLS---SNMLAIALERLHEEKDSRVKYSITD 298 Query: 135 IDHHVFPAN-YDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIY 177 + F N +D V D + P L + +P G + Sbjct: 299 ALVYQFEDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKVL 342 >2WHD-A nrPDB Length = 351 Score = 27.4 bits (59), Expect = 5.1, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 36/114 (31%), Gaps = 8/114 (7%) Query: 28 SEKSQFCFCGHVLTITQNFGSRLGVAA--RVWDAALSLCNYFESQNVDFRGKKVIELGAG 85 + S V+ T RL + W+ +S C + FR K + +G G Sbjct: 127 TSDSTTVLADTVVVATGAVARRLYFSGSDTYWNRGISACAVCDGAAPIFRNKPIAVIGGG 186 Query: 86 TGIV--GILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDH 137 + G G V I + +QA + + QV W + Sbjct: 187 DSAMEEGNFLTKYGSQVYIIHRRNTFRASK-IMQARALSNPKIQV---VWDSEV 236 >4IE5-A nrPDB Length = 495 Score = 27.0 bits (58), Expect = 6.2, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 20/59 (33%), Gaps = 4/59 (6%) Query: 88 IVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDL 146 + ILA+L + Q + +PA + + W D P +DL Sbjct: 425 LTAILASLTARQNL---RREWHARCQSRIARTLPADQKPE-CRPYWEKDDASMPLPFDL 479 >6BPY-A nrPDB Length = 374 Score = 26.6 bits (57), Expect = 8.8, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 26/76 (34%), Gaps = 3/76 (3%) Query: 57 WDAALSLCNYFESQNVDFRGKKVIELGAGTGIV--GILAALQGGDVTITDLPLALEQIQG 114 W +S C + FR K + +G G + A G VT+ L + Sbjct: 139 WQNGISACAVCDGAVPIFRNKPLYVIGGGDSAAEEAMFLAKYGSSVTVLVRRDKLRASKA 198 Query: 115 NVQANVPAGGQAQVRA 130 + + A + VR Sbjct: 199 -MAKRLLAHPKVTVRF 213 >2Q7X-A nrPDB Length = 326 Score = 26.6 bits (57), Expect = 8.9, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 33/91 (36%), Gaps = 20/91 (21%) Query: 74 FRGKKVIELGAGTGIVGILAALQGGD------VTITDLPLALEQIQGNVQANVPAGGQ-- 125 R K+ +G GTG IL +L+ D VT+ D + +++ N+Q P G Sbjct: 2 MRKPKITVIGGGTGSPVILKSLREKDVEIAAIVTVADDGGSSGELRKNMQQLTPPGDLRN 61 Query: 126 ------------AQVRALSWGIDHHVFPANY 144 +V + D F + Sbjct: 62 VLVAMSDMPKFYEKVFQYRFSEDAGAFAGHP 92 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.130 0.329 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,159,735 Number of Sequences: 36641 Number of extensions: 291262 Number of successful extensions: 953 Number of sequences better than 10.0: 64 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 874 Number of HSP's gapped (non-prelim): 106 length of query: 226 length of database: 10,336,785 effective HSP length: 94 effective length of query: 132 effective length of database: 6,892,531 effective search space: 909814092 effective search space used: 909814092 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.6 bits)