BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96329 (436 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IX5-A nrPDB 907 0.0 2EBA-A nrPDB 267 6e-72 3SF6-A nrPDB 252 2e-67 3GNC-A nrPDB 246 1e-65 1SIR-A nrPDB 231 4e-61 4W9U-A nrPDB 225 4e-59 3SWO-A nrPDB 214 7e-56 5LNX-A nrPDB 192 2e-49 1UKW-A nrPDB 178 4e-45 4N5F-A nrPDB 175 4e-44 6FAH-C nrPDB 172 2e-43 4U83-A nrPDB 169 3e-42 1JQI-A nrPDB 168 4e-42 2CX9-A nrPDB 168 5e-42 3PFD-A nrPDB 165 3e-41 4O5M-A nrPDB 164 1e-40 5OL2-C nrPDB 163 1e-40 2JIF-A nrPDB 162 4e-40 2VIG-A nrPDB 161 5e-40 4KTO-A nrPDB 160 1e-39 2DVL-A nrPDB 160 1e-39 4M9A-A nrPDB 159 3e-39 3OWA-A nrPDB 157 7e-39 4L1F-A nrPDB 152 2e-37 3MPI-A nrPDB 148 4e-36 1IVH-A nrPDB 144 5e-35 1BUC-A nrPDB 143 1e-34 3MDE-A nrPDB 142 2e-34 2Z1Q-A nrPDB 141 5e-34 2A1T-A nrPDB 141 7e-34 4IV6-A nrPDB 130 1e-30 2PG0-A nrPDB 129 2e-30 5IDU-A nrPDB 126 2e-29 3B96-A nrPDB 124 7e-29 5JSC-A nrPDB 122 3e-28 3NF4-A nrPDB 118 5e-27 4IRN-A nrPDB 115 3e-26 1RX0-A nrPDB 114 1e-25 6ES9-A nrPDB 114 1e-25 5ZW7-A nrPDB 111 8e-25 3R7K-A nrPDB 99 3e-21 4RM7-A nrPDB 86 3e-17 3P4T-A nrPDB 84 2e-16 1R2J-A nrPDB 80 2e-15 5AHS-A nrPDB 78 6e-15 6CY8-B nrPDB 69 3e-12 2FON-A nrPDB 64 1e-10 4HR3-A nrPDB 63 3e-10 5GJ7-A nrPDB 60 1e-09 5EZ3-A nrPDB 57 2e-08 4JEK-A nrPDB 55 4e-08 4X28-A nrPDB 55 7e-08 2WBI-A nrPDB 55 8e-08 4Y9J-A nrPDB 55 8e-08 5YS9-A nrPDB 54 1e-07 1W07-A nrPDB 52 5e-07 5XDD-A nrPDB 50 3e-06 5Y9D-A nrPDB 49 3e-06 3MKH-A nrPDB 48 1e-05 2C12-A nrPDB 45 9e-05 4X28-D nrPDB 42 5e-04 1IS2-A nrPDB 40 0.002 3M9V-A nrPDB 39 0.004 5K3G-A nrPDB 39 0.006 5K3J-A nrPDB 36 0.039 4XVX-A nrPDB 33 0.21 5UR2-A nrPDB 32 0.70 5LVW-A nrPDB 31 1.2 2RFQ-A nrPDB 29 3.2 5JIP-A nrPDB 29 4.9 >2IX5-A nrPDB Length = 436 Score = 907 bits (2345), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/436 (100%), Positives = 436/436 (100%) Query: 1 MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQ 60 MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQ Sbjct: 1 MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQ 60 Query: 61 AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAI 120 AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAI Sbjct: 61 AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAI 120 Query: 121 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG 180 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG Sbjct: 121 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG 180 Query: 181 SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLK 240 SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLK Sbjct: 181 SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLK 240 Query: 241 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM 300 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM Sbjct: 241 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM 300 Query: 301 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ 360 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ Sbjct: 301 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ 360 Query: 361 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR Sbjct: 361 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 Query: 421 EVTGIASFKPATRSRL 436 EVTGIASFKPATRSRL Sbjct: 421 EVTGIASFKPATRSRL 436 >2EBA-A nrPDB Length = 385 Score = 267 bits (683), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 149/384 (38%), Positives = 220/384 (57%), Gaps = 3/384 (0%) Query: 47 DYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK 106 D+Y DLLTPEE+ ++K R +EKE P + ++WE+ FP H+ P+ +G G ++ Sbjct: 3 DFYALEDLLTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLP 62 Query: 107 -GYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQ 165 YG G+S A + E+ RVD+ +F+ V SSL M I GSE QK ++LP LA+ Sbjct: 63 PEYGGAGVSSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLAR 122 Query: 166 LNTVACWALTEPDNGSDASGLGTTATKVEGG-WKINGQKRWIGNSTFADLLIIFARNTTT 224 V C+ LTEPD GSD G T + EG W +NG K WI N A L +I+A++ Sbjct: 123 GEMVGCFGLTEPDGGSDPYGNMKTRARREGDTWVLNGTKMWITNGNLAHLAVIWAKDEG- 181 Query: 225 NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVL 284 ++ GF+V D PG +A ++ K+ LR +++L+ V VP+ RLP + L Sbjct: 182 GEVLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRLPKALGLKAPLSCL 241 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 +R +AW +G +Y+ + K R FG PLA QL Q KL +ML L+ Sbjct: 242 TQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGLLLA 301 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 WRL +L + G++TP Q SL K KA + A + R++LGG+GI ++ + +LE + Sbjct: 302 WRLARLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLETV 361 Query: 405 YTYEGTYDINTLVTGREVTGIASF 428 YTYEGT+D++TLV GRE+TG+ +F Sbjct: 362 YTYEGTHDVHTLVLGREITGLNAF 385 >3SF6-A nrPDB Length = 403 Score = 252 bits (643), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 133/384 (34%), Positives = 210/384 (54%), Gaps = 3/384 (0%) Query: 47 DYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFH-ITPKLGAMGVAGGSI 105 D N +L+ EE+ IR VR +++ + P + ++E E P + +LG +G+ G + Sbjct: 22 DLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVELGELGLLGMHL 81 Query: 106 KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQ 165 KGYGC G+S A +A E+ D+ + + V SL M I GS+ QK+++LP +A Sbjct: 82 KGYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPDMAS 141 Query: 166 LNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN 225 + + C+ LTEPD+GSD +G+ T AT+ W + G K WI N + AD+ +++AR T Sbjct: 142 GHRIGCFGLTEPDHGSDPAGMRTRATRSGDDWILTGTKMWITNGSVADVAVVWAR--TDE 199 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLA 285 I GF+V D PG A I +K+ LR +++L V +PD RLPG S + L Sbjct: 200 GIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDSARLPGATSLGAPLRCLN 259 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 +R + + +G + + Y R+QF P+ FQL QQKL M FL+ Sbjct: 260 EARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQLTQQKLADMTLEYGKGFLLAL 319 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 L + + G++ P Q SLGK +A E A R +LG +GI ++ V + +LE + Sbjct: 320 HLGRQKDAGELAPEQVSLGKLNNVREAIEIARTARTVLGASGITGEYPVMRHANNLESVL 379 Query: 406 TYEGTYDINTLVTGREVTGIASFK 429 TYEGT +++TL+ G+ +TG+ +F+ Sbjct: 380 TYEGTSEMHTLIIGQALTGVGAFR 403 >3GNC-A nrPDB Length = 399 Score = 246 bits (628), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 146/399 (36%), Positives = 220/399 (55%), Gaps = 5/399 (1%) Query: 33 PQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHIT 92 P + A+TF D + L +E+ +R + ++AP +TE + I Sbjct: 2 PGSMAAATFH--WDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIF 59 Query: 93 PKLGAMGVAGGSI-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCG 151 ++G +G+ G +I + YG PGL + + E+ RVD+ + + V SSL M+ I G Sbjct: 60 REMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFG 119 Query: 152 SEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTF 211 S+AQKEKYLP LA + C+ LTEP++GSD + T A KV GG+ ++G K WI NS Sbjct: 120 SDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGGYSLSGSKMWITNSPI 179 Query: 212 ADLLIIFAR--NTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDED 269 AD+ +++A+ ++I GFI++K GL A I K+GLR G+I+L FVP+E+ Sbjct: 180 ADVFVVWAKLDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEEN 239 Query: 270 RLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQK 329 LP V + L +R +AW +G + + + +Y+ +RKQFG PLAA QL Q+K Sbjct: 240 ILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKK 299 Query: 330 LVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGIL 389 L M + RL ++ + G S+ K KA + A L R++LGGNGI Sbjct: 300 LADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGIS 359 Query: 390 ADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASF 428 +F VA+ +LE + TYEGT+DI+ L+ GR TGI +F Sbjct: 360 DEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAF 398 >1SIR-A nrPDB Length = 394 Score = 231 bits (590), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 140/380 (36%), Positives = 202/380 (53%), Gaps = 3/380 (0%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGC 110 + LT +E IR R ++ + P + F I ++G +GV G +IKGYGC Sbjct: 12 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGC 71 Query: 111 PGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVA 170 G+S A + E+ RVD+ + + V SSL M I GSE Q++KYLP LA+ + Sbjct: 72 AGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLG 131 Query: 171 CWALTEPDNGSDASGLGTTA--TKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQIN 228 C+ LTEP++GSD S + T A + +NG K WI NS ADL +++AR I Sbjct: 132 CFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWAR-CEDGCIR 190 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSR 288 GF+++K GL A +I K LR G I++ V VP+E+ LPG +S L +R Sbjct: 191 GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNAR 250 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 +AW +G S +Y +R QFG PLA QL Q+KL ML + +L Sbjct: 251 YGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLG 310 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 +L + + P SL K KA + A R++LGGNGI ++ V + +LE + TYE Sbjct: 311 RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 370 Query: 409 GTYDINTLVTGREVTGIASF 428 GT+DI+ L+ GR +TGI +F Sbjct: 371 GTHDIHALILGRAITGIQAF 390 >4W9U-A nrPDB Length = 395 Score = 225 bits (573), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 131/386 (33%), Positives = 207/386 (53%), Gaps = 6/386 (1%) Query: 47 DYYHFNDLLTPEEQAIRKKVRECMEKEVAP-IMTEYWEKAEFP--FHITPKLGAMGVAGG 103 D + + LT +E+ IR + + P + Y E+ P FH+ + G +GV Sbjct: 11 DPFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQAGLLGVT-- 68 Query: 104 SIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSL 163 + YG S A + E+ R+D+ + + V SSL M I GS+ Q++KYLP L Sbjct: 69 LPEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGL 128 Query: 164 AQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTT 223 + C+ LTEPD GSD +G+ T A K++GG++++G K WI NS AD+ +++A++ Sbjct: 129 VSGELIGCFGLTEPDAGSDPAGMKTRAEKIDGGYRLSGSKMWISNSPIADVFVVWAKSAA 188 Query: 224 -TNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSK 282 N I GFI++K GL A KI K+ LR G+I++ V V ++ LP V+ + Sbjct: 189 HDNAIRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAILPNVSGLKGPFG 248 Query: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFL 342 L +R ++W +G + + +Y +RKQF PLA QL Q+KL M + Sbjct: 249 CLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQTEIALGIQ 308 Query: 343 MGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLE 402 R+ +L++ G+M P S+ K KA + A R++ GGNGI ++ V + +LE Sbjct: 309 ASLRVGRLFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHVMRHAQNLE 368 Query: 403 PIYTYEGTYDINTLVTGREVTGIASF 428 + TYEGT+D++ L+ GR TGI +F Sbjct: 369 TVNTYEGTHDVHALILGRAQTGIQAF 394 >3SWO-A nrPDB Length = 399 Score = 214 bits (544), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 126/404 (31%), Positives = 210/404 (51%), Gaps = 10/404 (2%) Query: 29 SVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFP 88 S+ + ST+ P + + + LL +E+ I VR+ ++ + P + ++E A P Sbjct: 2 SMTLTAPSKKSTYAPL--ELFDTDRLLDQDERDIAATVRQFVDTRLKPNVEGWFESATLP 59 Query: 89 FHITPKLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIA 148 + + G +GV G ++GYGC G + + +A E+ D+ +F+ V SL M +I Sbjct: 60 SELAKEFGNLGVLGMHLQGYGCAGTNAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIY 119 Query: 149 LCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGN 208 GSE QK ++LP LA + + C+ LTEPD GS+ +G+ T A + W +NG K WI N Sbjct: 120 RYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRDGSDWILNGTKMWITN 179 Query: 209 STFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDE 268 AD+ ++A+ T + I GF+V D PG A +I K+ LR +++L NV +P Sbjct: 180 GNLADVATVWAQ--TDDGIRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPAS 237 Query: 269 DRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQ 328 +LP L +R + + +G + + Y + R+ F PL+ +QL Q+ Sbjct: 238 AQLPLAEGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQE 297 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRE---LLGG 385 KL M + L+ L ++ + + P Q SLGK + RE ++ RE LLGG Sbjct: 298 KLANMTVELGKGMLLAIHLGRIKDAEGVRPEQISLGKL---NNVREAIAIARECRTLLGG 354 Query: 386 NGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASFK 429 +GI ++ + +LE + TYEGT +++ L G+ +TG A+F+ Sbjct: 355 SGITLEYSPLRHANNLESVLTYEGTSEMHLLSIGKALTGKAAFR 398 >5LNX-A nrPDB Length = 379 Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 126/376 (33%), Positives = 193/376 (51%), Gaps = 7/376 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKA-EFPFHITPKLGAMGVAGGSI-KGYGCPG 112 +T E+ +RK VR+ KE+AP E EK EFPF + K+G G+ G + + YG G Sbjct: 3 VTQEQVMMRKMVRDFARKEIAP-AAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAG 61 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 + + +A EI+R+ A+ + VH+S+G I G+E QK KY+P+LA + + + Sbjct: 62 ADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAF 121 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR---NTTTNQING 229 ALTEP +GSDA L TTA K G + +NG K +I N AD+ I FA + + I+ Sbjct: 122 ALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGISA 181 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLAVSR 288 FIV+K+ PG K K+GL +++ N VP+ + L + F L V R Sbjct: 182 FIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVGR 241 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A Q +GI+ + Y K+R QFG P+AA Q KL M +A + + Sbjct: 242 IGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHAA 301 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L+ G +AS+ K + S A + A ++ GG G + D+ V + D + YE Sbjct: 302 DLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYE 361 Query: 409 GTYDINTLVTGREVTG 424 GT +I L+ + + G Sbjct: 362 GTNEIQRLIISKYLLG 377 >1UKW-A nrPDB Length = 379 Score = 178 bits (451), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 119/373 (31%), Positives = 192/373 (51%), Gaps = 6/373 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGL 113 LT E++ ++ R ++ + P+ EY EK E P+ + KL +G+ I + YG GL Sbjct: 5 LTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGL 64 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 + I E+A T I + S LG+ + L G+E QKE++L L + +A +A Sbjct: 65 KMLDEVIVGEELAYACMGIYT-IPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFA 123 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQING---F 230 L+EP NGSDA+ L T A + + +NG K WI N A+ +++FA + G Sbjct: 124 LSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRHKGVVAL 183 Query: 231 IVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL-PGVNSFQDTSKVLAVSRV 289 +V++ PG KA KI K+G R +++ ++V VP E+RL F+ + L +R+ Sbjct: 184 VVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKTRI 243 Query: 290 MVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCK 349 VA +G++ D +Y KER+ FG P+A FQ Q KLV ML ++ + + Sbjct: 244 PVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYYAAW 303 Query: 350 LYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEG 409 L + G +++ KA+ S A E A+ ++ GG G + +F V K D++ YEG Sbjct: 304 LADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQIYEG 363 Query: 410 TYDINTLVTGREV 422 T +I L+ R + Sbjct: 364 TNEIQRLIIARHI 376 >4N5F-A nrPDB Length = 385 Score = 175 bits (443), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 118/378 (31%), Positives = 182/378 (48%), Gaps = 7/378 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYG 109 ++L T +++ IR R + +AP ++ A P I +LG +G+ G + + G Sbjct: 9 MDELYTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELG 68 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 A A+A E+A DA+C+T + VH+S+G I G+ AQK+++L +A + Sbjct: 69 GSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVI 128 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR---NTTTNQ 226 + LTEP GS+A+ L T A +G W +NG K+++ N A + I+FA Sbjct: 129 GAFCLTEPHAGSEANNLRTRAELRDGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEAGKRG 188 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV--NSFQDTSKVL 284 I+ F+V D PG K K+G+R I +N +P ED L G + L Sbjct: 189 ISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIP-EDNLLGNRGEGLKIALSNL 247 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 R+ +A Q +GI+ +D RY ER QFG P+A Q QQKL M + A L+ Sbjct: 248 EGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLLV 307 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 KL G +AS K + S A S ++ GG G L D+ V + + D Sbjct: 308 HHAAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARIT 367 Query: 405 YTYEGTYDINTLVTGREV 422 YEGT ++ +V R++ Sbjct: 368 QIYEGTSEVQRMVIARQL 385 >6FAH-C nrPDB Length = 379 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 119/369 (32%), Positives = 180/369 (48%), Gaps = 6/369 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVA-PIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPG 112 + + + IRK R+ EKE+ I+ E E EFP I K+ G G I K G G Sbjct: 3 FSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSG 62 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 + I E ARV S ++ +SL + L G+E Q EKYL + + Sbjct: 63 GDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAF 122 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTT---TNQING 229 ALTEP GSDA G+ TTA + + +NG+K +I + D +I+A+ T I+ Sbjct: 123 ALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISA 182 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSKVLAVSR 288 FIV + G+ K +K+GL DI++++V VP E+RL VN F + K L V R Sbjct: 183 FIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGR 242 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + VA Q IG++ G D +Y KERKQFG +A FQ + M ++A L+ + Sbjct: 243 LGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAA 302 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L + + +AS+ K + S E + ++ GG G + ++ V + + D YE Sbjct: 303 SLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYE 362 Query: 409 GTYDINTLV 417 GT + +V Sbjct: 363 GTSQVQQMV 371 >4U83-A nrPDB Length = 382 Score = 169 bits (427), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 114/372 (30%), Positives = 182/372 (48%), Gaps = 5/372 (1%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGG-SIKGYGCPG 112 LLT ++ IR+ R+ ++ +AP + FP ++GA+G G + + +G Sbjct: 9 LLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGSD 68 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 L + A A+A EIA D +CST + VHSS+G + I G+E QK ++LP +A + + Sbjct: 69 LDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGF 128 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARN---TTTNQING 229 ALTEP GSDAS L T A + I+G K++I + +++I+FA I+ Sbjct: 129 ALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGISA 188 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLAVSR 288 FIV D PG + + +K+G + N+ VP E+RL ++ L R Sbjct: 189 FIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGGR 248 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A Q +G++ ++ Y +ER FG P+ Q +L M ++ M Sbjct: 249 IGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAA 308 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L E G+ +AS+ K S A + S ++ GG G LAD+ V + + D+ YE Sbjct: 309 ALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQIYE 368 Query: 409 GTYDINTLVTGR 420 GT D+ LV R Sbjct: 369 GTSDVQRLVIAR 380 >1JQI-A nrPDB Length = 388 Score = 168 bits (426), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 112/374 (29%), Positives = 185/374 (49%), Gaps = 8/374 (2%) Query: 51 FNDLLTPE-EQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGY 108 + + PE Q +R+ R+ EKE+ PI + ++ FP K+G +G+ + + Sbjct: 5 YQSVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEEL 64 Query: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNT 168 GL A +IA EI+R AS + V++SL + I GS QK++++ + Sbjct: 65 SGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDK 124 Query: 169 VACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ-- 226 + C+AL+EP NGSDA TTA + W +NG K WI NS A ++FA + Q Sbjct: 125 IGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNK 184 Query: 227 -INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL--PGVNSFQDTSKV 283 I+ F+V PGL K +K+G+R +++ ++ +P E+ L PG+ F+ + Sbjct: 185 GISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMG-FKIAMQT 243 Query: 284 LAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLM 343 L + R+ +A Q +GI+ D +Y + R FGAPL Q Q KL M +++ L+ Sbjct: 244 LDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLL 303 Query: 344 GWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEP 403 WR L + + ++++ K S A + ++LGG G + + + + D Sbjct: 304 TWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARI 363 Query: 404 IYTYEGTYDINTLV 417 YEGT +I LV Sbjct: 364 TEIYEGTSEIQRLV 377 >2CX9-A nrPDB Length = 387 Score = 168 bits (425), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 120/374 (32%), Positives = 182/374 (48%), Gaps = 9/374 (2%) Query: 58 EEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGLSIT 116 EE+ + RE ++ EVAP E FP+ + KL GV G + + YG GLS Sbjct: 10 EERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAYGGAGLSTR 69 Query: 117 ANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTE 176 A IA D + + + H+SL I L GSEAQKE +LP LA + W LTE Sbjct: 70 LFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLTE 129 Query: 177 PDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR-------NTTTNQING 229 P +GSDA+ L T A KVEGGW++NG K++I + A + ++ AR I+ Sbjct: 130 PGSGSDAAALKTKAEKVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSPERKHQGISA 189 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL-PGVNSFQDTSKVLAVSR 288 F + GLK + K+GL ++L+++FVP+E L F D +VL R Sbjct: 190 FAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGFYDVLRVLDGGR 249 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A +G+ D Y K R+ FG P+A F+ KL + ++A L+ + Sbjct: 250 IGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARLLYLKAA 309 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 +L + G+ +A+ K + S A + ++LGG G + D+ V + + D E Sbjct: 310 ELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWRDARLTRIGE 369 Query: 409 GTYDINTLVTGREV 422 GT +I LV R + Sbjct: 370 GTSEILKLVIARRL 383 >3PFD-A nrPDB Length = 393 Score = 165 bits (418), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 124/379 (32%), Positives = 179/379 (47%), Gaps = 12/379 (3%) Query: 51 FNDLLTPEEQ-AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGY 108 F PEE A+R+ +R EKE+AP E EKA FP L + G + + + Y Sbjct: 14 FELFQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFSAIHVPEEY 73 Query: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNT 168 G G A I E+ARVD S S V+ LG + + L GSE K++ LP++A Sbjct: 74 GGQGADSVATCIVIEEVARVDCSASLIPAVNK-LGTMGLILRGSEELKKQVLPAVASGEA 132 Query: 169 VACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWI---GNSTFADLLIIFARNTTTN 225 +A +AL+E + GSDA+ + T A W +NG K WI G ST+ ++ + + N Sbjct: 133 MASYALSEREAGSDAASMRTRAVADGDDWILNGSKCWITNGGKSTWYTVMAVTDPDKGAN 192 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL---PGVNSFQDTSK 282 I+ F+V KD G K+G++ ++ +N +P DR+ PG F+ Sbjct: 193 GISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPG-DRIIGEPGTG-FKTALA 250 Query: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFL 342 L +R + Q +GI+ G D Y KERKQFG P++ Q Q L M ++A L Sbjct: 251 TLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARL 310 Query: 343 MGWRLCKLYETGQMTPGQASLG-KAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 M + E G+ G S K + S A E + +L GG G DF V + D Sbjct: 311 MVYSAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDA 370 Query: 402 EPIYTYEGTYDINTLVTGR 420 + YEGT I +V R Sbjct: 371 KITQIYEGTNQIQRVVMSR 389 >4O5M-A nrPDB Length = 390 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 115/376 (30%), Positives = 178/376 (47%), Gaps = 11/376 (2%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGL 113 L E +A+R VR E +AP+ E +FP H+ + G +GV G + + YG G+ Sbjct: 13 LGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYGGAGM 72 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 A+ IA EI+R AS HS+L + I GS Q+ KYLP L V A Sbjct: 73 GYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHVGALA 132 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQINGF 230 ++EP GSD + A K + +NG K WI N AD+L+++A+ + I+ F Sbjct: 133 MSEPGAGSDVVSMKLAAEKRGDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGPRGISAF 192 Query: 231 IVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL----PGVNSFQDTSKVLAV 286 I++K G + +K+G+R +++ ++ VP E+ L GVN L Sbjct: 193 IIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMSG---LDY 249 Query: 287 SRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWR 346 RV++A P+GI D+ Y+ ERKQF P+ FQL Q KL M A + Sbjct: 250 ERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAYVYA 309 Query: 347 LCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYT 406 + + G+ T A+ + + A + A + LGGNG + D+ + D + Sbjct: 310 VAAACDRGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKLYEI 369 Query: 407 YEGTYDINTLVTGREV 422 GT +I ++ GRE+ Sbjct: 370 GAGTSEIRRMLIGREL 385 >5OL2-C nrPDB Length = 378 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 110/370 (29%), Positives = 181/370 (48%), Gaps = 5/370 (1%) Query: 53 DLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCP 111 DL + + Q +++ E EV P+ TE E+ FP+ K+ G+ G K YG Sbjct: 2 DLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGE 61 Query: 112 GLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVAC 171 G +A E++RV + + H+SLG I G+E QK+K+L LA + Sbjct: 62 GGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGA 121 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFA---RNTTTNQIN 228 + LTEP+ G+DASG TTA + +NG K +I N+ D+ ++ A ++ I+ Sbjct: 122 FGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAIAGDIYVVMAMTDKSKGNKGIS 181 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLAVS 287 FIV+K PG K+G+R +++ ++ +P E+ L F+ L Sbjct: 182 AFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDGG 241 Query: 288 RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRL 347 R+ +A Q +G++ G D +Y+KER QFG PL+ FQ Q +L M VQA + ++ Sbjct: 242 RIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQA 301 Query: 348 CKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTY 407 + G+ +A++ K + + A E + +L GG G D+ V + D + Y Sbjct: 302 AINKDLGKPYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIY 361 Query: 408 EGTYDINTLV 417 EGT ++ +V Sbjct: 362 EGTSEVQRMV 371 >2JIF-A nrPDB Length = 404 Score = 162 bits (409), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 112/365 (30%), Positives = 180/365 (49%), Gaps = 6/365 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGL 113 T EE I+ V++ ++++AP+++ E ++ + L G+ G + YG G Sbjct: 29 FTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGA 88 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 S + + E+A+VDAS + F + ++L I G+E QK YLP L V + Sbjct: 89 SFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFC 147 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQINGF 230 L+E GSD+ L T A K + +NG K WI ++ A L ++ A T I F Sbjct: 148 LSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYKGITSF 207 Query: 231 IVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLAVSRV 289 +V +D PGL K NK+GLR + +NV VP+ + L + + ++ L R+ Sbjct: 208 LVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNEGRI 267 Query: 290 MVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCK 349 +A Q +G++ G +D Y+KER QFG L FQ Q ++ + ++A L+ + + Sbjct: 268 GIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYNAAR 327 Query: 350 LYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEG 409 L E G+ +AS+ K + S A +T S E +GG G D+ V K F D + YEG Sbjct: 328 LLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTIYEG 387 Query: 410 TYDIN 414 +I Sbjct: 388 ASNIQ 392 >2VIG-A nrPDB Length = 391 Score = 161 bits (408), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 112/368 (30%), Positives = 180/368 (48%), Gaps = 8/368 (2%) Query: 57 PE-EQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGLS 114 PE Q + + R+ EKE+ PI + ++ FP K+G +G+ + + G GL Sbjct: 7 PETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLD 66 Query: 115 ITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWAL 174 A AIA EI+R AS + V++SL + I GS+ QK+ ++ + + C+AL Sbjct: 67 YLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFAL 126 Query: 175 TEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFA---RNTTTNQINGFI 231 +EP NGSDA TTA W +NG K WI N+ A ++FA R I+ F+ Sbjct: 127 SEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSISAFL 186 Query: 232 VKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL--PGVNSFQDTSKVLAVSRV 289 V PGL K +K+G+R +++ ++ +P + L PG+ F+ + L + R+ Sbjct: 187 VPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMG-FKIAMQTLDMGRI 245 Query: 290 MVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCK 349 +A Q +GI+ D Y + R FGAPL Q+ Q KL M +++ L+ WR Sbjct: 246 GIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAM 305 Query: 350 LYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEG 409 L + + +A++ K S A + ++LGG G + + + + D YEG Sbjct: 306 LKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEG 365 Query: 410 TYDINTLV 417 T +I LV Sbjct: 366 TSEIQRLV 373 >4KTO-A nrPDB Length = 410 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 113/377 (29%), Positives = 177/377 (46%), Gaps = 5/377 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAG-GSIKGYG 109 N L E A+R VR + +AP+ + FP + ++G +G+ G + + +G Sbjct: 29 LNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAHG 88 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 GL A+ +A EI+R AS HS+L + I G AQK +YLP L V Sbjct: 89 GAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEHV 148 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQ 226 A++EP GSD + A K + +NG K WI N AD+L+++A+ Sbjct: 149 GALAMSEPGAGSDVVSMKLKADKRGDRYVLNGSKMWITNGPDADVLVVYAKTDPAAGPRG 208 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLA 285 I F+V+K PG A + +K+G+R +++ + VP+E+ L GV + L Sbjct: 209 ITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLMSGLD 268 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 RV+++ P+GI D+ YL ERKQFG P+ FQL Q KL M + A + Sbjct: 269 YERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAARAYVY 328 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 + + G+ A+ + + KA A + LGGNG D+ + D + Sbjct: 329 AVAAACDRGETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAKLYE 388 Query: 406 TYEGTYDINTLVTGREV 422 GT +I ++ GRE+ Sbjct: 389 IGAGTSEIRRMLIGREL 405 >2DVL-A nrPDB Length = 372 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 121/376 (32%), Positives = 187/376 (49%), Gaps = 16/376 (4%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGL 113 LT E++ + VR + + P+ EY KAE+P+ L +G+ G + + +G GL Sbjct: 3 LTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 A+A E+A D S + + V S L + GSEAQK +YL LA+ + + Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVK 233 LTEP GSDA L A +V+GG+ +NG K WI ++ A L ++ AR T I+ F+V+ Sbjct: 123 LTEPQAGSDAKSLRAEARRVKGGFVLNGVKSWITSAGHAHLYVVMAR--TEKGISAFLVE 180 Query: 234 KDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVS------ 287 K PGL + K+GL ++ L+ VFVP+E N + + LA + Sbjct: 181 KGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEE------NLLGEEGRGLAYALAGLDS 234 Query: 288 -RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWR 346 RV VA Q +GI+ G +++ Y +ER+QFG L Q K+ M + A + Sbjct: 235 GRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLE 294 Query: 347 LCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYT 406 + + G+ +AS K + S+ A E ++LGG G D+ V + + D + Sbjct: 295 AARKKDRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEI 354 Query: 407 YEGTYDINTLVTGREV 422 YEGT +I LV RE+ Sbjct: 355 YEGTSEIQRLVIAREL 370 >4M9A-A nrPDB Length = 385 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 114/377 (30%), Positives = 180/377 (47%), Gaps = 5/377 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YG 109 +DL T +++ I R + +AP ++ ++ P + ++G +G G + +G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 A A+A EIA ASC+T + VH+S+G + G+ QKE++L LA TV Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR---NTTTNQ 226 ++LTEP GS+A L T A +G W +NG K+++ N A L I+FA + Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELRDGKWILNGSKQFVTNGARAGLAIVFAMTDPDEGKRG 188 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLA 285 ++ F+V D PG K K+G+R I L+N +P E+ L + L Sbjct: 189 LSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSNLE 248 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 R+ +A Q GI+ +D RY +ER QFG P+A Q +KL M + A L+ Sbjct: 249 GGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLLTH 308 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 +L G +AS K + S A S ++ GG G L D+ V + + D Sbjct: 309 HAARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARITQ 368 Query: 406 TYEGTYDINTLVTGREV 422 YEGT ++ +V R++ Sbjct: 369 IYEGTSEVQRMVIARQL 385 >3OWA-A nrPDB Length = 597 Score = 157 bits (398), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 118/402 (29%), Positives = 195/402 (48%), Gaps = 33/402 (8%) Query: 47 DYYHFNDLLTPEE-----QAIRKKVRECMEKEVAPIMTEYWEKAEF--PFHITPKLGAMG 99 D + + TPE+ + I K + + EV P + EY E+ EF + + G +G Sbjct: 20 DEITIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPEL-EYLEQHEFDRSVRLLKEAGELG 78 Query: 100 VAGGSI-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEK 158 + G + + YG GL ++A+ + +R T H +G L I L G+E QK+K Sbjct: 79 LLGADVPEEYGGIGLDKVSSALIAEKFSRAGGFAITH-GAHVGIGSLPIVLFGNEEQKKK 137 Query: 159 YLPSLAQLNTVACWALTEPDNGSDASGLGTTAT-KVEG-GWKINGQKRWIGNSTFADLLI 216 YLP LA +A +ALTEP +GSDA G TTA EG + +NG+K+WI NS FAD+ I Sbjct: 138 YLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFI 197 Query: 217 IFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS 276 ++A+ + FIV+KD G+ + K+G++ ++L++ VP E+ L + Sbjct: 198 VYAK-IDGEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGK 256 Query: 277 FQDTS-KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLG 335 + +L + R + +G + ++ +Y +R+QF P+A F L Q+KL M Sbjct: 257 GHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAA 316 Query: 336 NVQAMFLMGWRLCKLYET-------GQMTPGQA------------SLGKAWISSKARETA 376 A +R L+E+ ++ G+A SL K + S T Sbjct: 317 KTYAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTV 376 Query: 377 SLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVT 418 G ++ GG G +A++ + + + D +EGT +IN L+ Sbjct: 377 DEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIV 418 >4L1F-A nrPDB Length = 383 Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 109/375 (29%), Positives = 180/375 (48%), Gaps = 7/375 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYG 109 FN LT ++Q I+ E EK +AP + E + + + K+G G G + YG Sbjct: 3 FN--LTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 GL + + +A E+++VD + + SL I + G+E QK+KYL +A+ V Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQING 229 + LTEP G+DAS TTA + +NG K +I N AD ++FA + ++G Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVLKGDKYILNGSKIFITNGKEADTYVVFAMTDKSQGVHG 180 Query: 230 ---FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLA 285 FI++K PG + KI +K+G +++ ++ VP E+ L F+ + L Sbjct: 181 ISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAMETLD 240 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 R+ VA Q +GI+ G +Y KER+QFG ++ FQ Q + M ++A + + Sbjct: 241 GGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARYLVY 300 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 L G+ A++ K + S A E + ++ GG G D+ + + + Sbjct: 301 HAAMLKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAKITQ 360 Query: 406 TYEGTYDINTLVTGR 420 YEGT + +VT R Sbjct: 361 IYEGTNQVMRIVTSR 375 >3MPI-A nrPDB Length = 397 Score = 148 bits (374), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 109/386 (28%), Positives = 192/386 (49%), Gaps = 21/386 (5%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPK-LGAMGVAGGSI-KGYGCPG 112 L+ E Q ++K+VR + K++ P ++ + FP+ + +G +G G I + YG G Sbjct: 5 LSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEYGGEG 64 Query: 113 LSI--TANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVA 170 + A I T EIAR ++ + + TI GSEA K+KY+P L+ + Sbjct: 65 MDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSAEFLG 124 Query: 171 CWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFA---RNTTTNQI 227 + +TEPD GSD + +TA W +NG K WI N+ AD+LI +A + + + Sbjct: 125 GFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTDKAAGSRGL 184 Query: 228 NGFIVK-KDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL--PGVNSFQDTSKV- 283 + F+++ ++ PG+K + + K+G G++ L NV VP E+ L PG D +++ Sbjct: 185 SAFVIEPRNFPGIKTSNL-EKLGSHASPTGELFLDNVKVPKENILGKPG-----DGARIV 238 Query: 284 ---LAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAM 340 L +R+ A +G++ D +Y ER+QFG P+ FQ+NQ + QM V+A Sbjct: 239 FGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVEAA 298 Query: 341 FLMGWRLCKLYETGQMTPG-QASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFC 399 L+ ++ + G++ G ++ K + A+ +LG G ++ VA+ + Sbjct: 299 RLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARFYR 358 Query: 400 DLEPIYTYEGTYDINTLVTGREVTGI 425 D Y EG+ +I ++ + G+ Sbjct: 359 DAPTYYMVEGSANICKMIIALDQLGV 384 >1IVH-A nrPDB Length = 394 Score = 144 bits (364), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 104/375 (27%), Positives = 175/375 (46%), Gaps = 9/375 (2%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFP--FHITPKLGAMGVAGGSIK-GYGCP 111 L+ E++ +R+ + + +++ +AP E EF +LG +GV G + YG Sbjct: 13 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGS 72 Query: 112 GLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVAC 171 GL + + EI+R + HS+L + + G+EAQKEKYLP L + Sbjct: 73 GLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGA 132 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT-----TTNQ 226 A++EP+ GSD + A K + +NG K WI N AD+LI++A+ + Sbjct: 133 LAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRG 192 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLA 285 I FIV+K PG +K +K+G+R +++ ++ +P + L N L Sbjct: 193 ITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLD 252 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 + R+++A P+G+ + D YL R+ FG + FQL Q K+ M + A + Sbjct: 253 LERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVY 312 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 + K + G T + + + A + A G + GGNG + DF + + D + Sbjct: 313 NVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYE 372 Query: 406 TYEGTYDINTLVTGR 420 GT ++ LV GR Sbjct: 373 IGAGTSEVRRLVIGR 387 >1BUC-A nrPDB Length = 383 Score = 143 bits (361), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 115/378 (30%), Positives = 184/378 (48%), Gaps = 11/378 (2%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK---- 106 FN LT +Q K + EK++AP +TE K + + +L ++G+ G + Sbjct: 3 FN--LTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYG 60 Query: 107 GYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQL 166 G G G + + +A E+A+ DA + + SL I G+EAQKEK+L L + Sbjct: 61 GSGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEG 120 Query: 167 NTVACWALTEPDNGSDASGLGTTATKVEGG-WKINGQKRWIGNSTFADLLIIFA---RNT 222 + + LTEP+ G+DASG T ATK + G + +NG K +I N AD+ I+FA ++ Sbjct: 121 TKLGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTDKSK 180 Query: 223 TTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL-PGVNSFQDTS 281 + I FI++ PG K +K+G+ Q +++ Q+V VP E+ L F+ Sbjct: 181 GNHGITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAM 240 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 L R+ VA Q +GI+ Y K+R QFG PL FQ KL M ++A Sbjct: 241 MTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAAR 300 Query: 342 LMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 + ++ + G+ A++ K S A + ++ GG G ++ VA+ D Sbjct: 301 NLVYKAACKKQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDA 360 Query: 402 EPIYTYEGTYDINTLVTG 419 + YEGT ++ +VTG Sbjct: 361 KITQIYEGTNEVQLMVTG 378 >3MDE-A nrPDB Length = 385 Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 107/382 (28%), Positives = 178/382 (46%), Gaps = 9/382 (2%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYG 109 F+ LT +++ + R+ +E+ P+ EY E+P + + +G+ I + +G Sbjct: 2 FSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFG 61 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 GL I + + T E+A T I ++ LG + + + G+ Q++KYL + + + Sbjct: 62 GLGLGIIDSCLITEELAYGCTGVQTAIEANT-LGQVPLIIGGNYQQQKKYLGRMTEEPLM 120 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT------T 223 + +TEP GSD +G+ T A K + INGQK WI N A+ + AR+ Sbjct: 121 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 180 Query: 224 TNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSK 282 + GFIV+ D PG++ + +G R I+ ++V VP E+ L G + F+ Sbjct: 181 SKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMG 240 Query: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFL 342 +R VA +G++ D +Y ERK FG LA Q L M V+ L Sbjct: 241 TFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARL 300 Query: 343 MGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLE 402 R ++G+ AS+ KA+ + A + A+ ++ GGNG ++ V K D + Sbjct: 301 SYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAK 360 Query: 403 PIYTYEGTYDINTLVTGREVTG 424 YEGT I ++ RE G Sbjct: 361 IYQIYEGTAQIQRIIIAREHIG 382 >2Z1Q-A nrPDB Length = 577 Score = 141 bits (356), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 113/387 (29%), Positives = 181/387 (46%), Gaps = 28/387 (7%) Query: 56 TPEE-----QAIRKKVRECMEKEVAPIMTEYWEKAEFPFHI--TPKLGAMGVAGGSI-KG 107 TPE+ + I + R +E+EV P++ E E E ++ K G +G+ + + Sbjct: 24 TPEDFDESVKEIARTTRTFVEREVLPLL-ERMEHGELELNVPLMRKAGELGLLAIDVPEE 82 Query: 108 YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 YG L + + E++ T+ H+S+G L + G+E QK KYLP LA Sbjct: 83 YGGLDLPKVISTVVAEELSGSGGFSVTYG-AHTSIGTLPLVYFGTEEQKRKYLPKLASGE 141 Query: 168 TVACWALTEPDNGSDASGLGTTATKVEGG--WKINGQKRWIGNSTFADLLIIFARNTTTN 225 +A + LTEP +GSDA T AT E G + +NG K+WI N+ FA L +FA+ Sbjct: 142 WIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAK-VDGE 200 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTS-KVL 284 F+V++D PGL K+G++ ++L++V VP E+ L + + VL Sbjct: 201 HFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGKGHKIAFNVL 260 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 V R + +G + ++ +Y +R QFG P+ F L QQKL +M + A Sbjct: 261 NVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAESAV 320 Query: 345 WRLCKLYET---GQMTPGQASLGKAWISSKARETASLGRELL-----------GGNGILA 390 +R L + G+ P G + +A LG E+L GG G Sbjct: 321 YRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGYSQ 380 Query: 391 DFLVAKAFCDLEPIYTYEGTYDINTLV 417 ++ + +A+ D +EGT +IN L+ Sbjct: 381 EYPIERAYRDARINRIFEGTNEINRLL 407 >2A1T-A nrPDB Length = 421 Score = 141 bits (355), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 105/379 (27%), Positives = 175/379 (46%), Gaps = 9/379 (2%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGC 110 F+ T +++ + R+ +E+ P+ EY + E+P + + +G+ I C Sbjct: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIP-ENC 95 Query: 111 PGLSI-TANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 GL + T +A +E + + +SLG + I + G++ QK+KYL + + + Sbjct: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT------T 223 + +TEP GSD +G+ T A K + INGQK WI N A+ + AR+ Sbjct: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 Query: 224 TNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSK 282 GFIV+ D PG++ + +G R I+ ++V VP E+ L G + F+ Sbjct: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 Query: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFL 342 +R +VA +G++ D +Y ERK FG L Q L +M V+ + Sbjct: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 Query: 343 MGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLE 402 R ++G+ AS+ KA+ A + A+ ++LGGNG ++ V K D + Sbjct: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 Query: 403 PIYTYEGTYDINTLVTGRE 421 YEGT I L+ RE Sbjct: 396 IYQIYEGTSQIQRLIVARE 414 >4IV6-A nrPDB Length = 388 Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 105/382 (27%), Positives = 177/382 (46%), Gaps = 20/382 (5%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGL 113 LT EE+ I K V + +EK+V P++ E +P + + +G+ G +I + YG + Sbjct: 7 LTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAV 66 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 S+ E+AR S + + H+ + L + L G+E QK+KYLP +A A A Sbjct: 67 SMPCYVQVAEELARGWMSLAGAMGGHTVVSKLLL-LFGTEEQKQKYLPRMATGELRATMA 125 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ-----IN 228 LTEP GSD + T A + + ING K WI N+ +DL+ + + Q ++ Sbjct: 126 LTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKGVS 185 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVP-------DEDRLPGVNSFQDTS 281 +V+K PG ++ K+G + V++ ++ + VP DE R F Sbjct: 186 ILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGR-----GFAQMM 239 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 K L V R+ VA + G++ ++ RY +ER+ FG P+ Q L M + A Sbjct: 240 KGLEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAAR 299 Query: 342 LMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 + + ++ GQ +A + K + S A + A + GG G ++ V + F D Sbjct: 300 SLLLSAAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDA 359 Query: 402 EPIYTYEGTYDINTLVTGREVT 423 + EGT +I V +++ Sbjct: 360 PLMIVGEGTNEIQRNVIAKQLV 381 >2PG0-A nrPDB Length = 385 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 93/375 (24%), Positives = 172/375 (45%), Gaps = 8/375 (2%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGL 113 L E R R+ +EKE P ++ ++ P K+G G + + YG Sbjct: 10 LREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNA 69 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 + + E+ +V +S I +H+ + IA G+E QK+K+LP + A Sbjct: 70 DFAYSVVINEELEKVGSSLVG-IGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIA 128 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ-----IN 228 +TEP GSD + + TTA K + +NGQK +I N ADL+++ + + I+ Sbjct: 129 MTEPGAGSDLANISTTAVKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPPHRGIS 188 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL-PGVNSFQDTSKVLAVS 287 +V++D PG + K+GL ++ Q+ VP + L F + L Sbjct: 189 LLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEEGKGFYYLMEKLQQE 248 Query: 288 RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRL 347 R++VA + ++ + +Y+K+R FG ++ FQ Q +L +M + R+ Sbjct: 249 RLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFVDRV 308 Query: 348 CKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTY 407 + + G+ + S+ K WI+ A+ A+ +L GG G + ++ +A+ + D+ Y Sbjct: 309 IEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAIY 368 Query: 408 EGTYDINTLVTGREV 422 GT ++ + R++ Sbjct: 369 AGTNEMMKTIIARQL 383 >5IDU-A nrPDB Length = 410 Score = 126 bits (316), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 94/329 (28%), Positives = 148/329 (44%), Gaps = 10/329 (3%) Query: 99 GVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEK 158 GV G G+G + A + +A D + F L LG I L G+ QK + Sbjct: 73 GVGGAQYGGHG-DTIDTRAVCLLRETLANHD-GLADFALAMQGLGSGAITLAGTHEQKIR 130 Query: 159 YLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIF 218 YLP +++ +A +AL+EPD GSD + + A + I+G K WI N AD ++F Sbjct: 131 YLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVF 190 Query: 219 ARNTT---TNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL--PG 273 AR I+ FIV D PGL+ + + I + + + VP L PG Sbjct: 191 ARTGEAPGARGISAFIVDADTPGLQIAERIDVIAPHPLAR--LHFDSARVPRSQMLGAPG 248 Query: 274 VNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQM 333 F+ + L V R VA +G + RK FG L FQL Q KL QM Sbjct: 249 -EGFKIAMRTLDVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQM 307 Query: 334 LGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFL 393 + + L+ +R L + G+ +A++ K S A++ +L GG G+ + Sbjct: 308 ALTIDSSALLVYRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTT 367 Query: 394 VAKAFCDLEPIYTYEGTYDINTLVTGREV 422 V + + ++ + YEG ++ L+ GR++ Sbjct: 368 VERLYREIRALRIYEGATEVQQLIVGRDL 396 >3B96-A nrPDB Length = 587 Score = 124 bits (311), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 104/354 (29%), Positives = 160/354 (45%), Gaps = 22/354 (6%) Query: 94 KLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSE 153 +LGA G+ S G GL T A + D + H S+G I L G++ Sbjct: 70 ELGAFGLQVPS--ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTK 127 Query: 154 AQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG--WKINGQKRWIGNSTF 211 AQKEKYLP LA TVA + LTEP +GSDA+ + T+A G + +NG K WI N Sbjct: 128 AQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGL 187 Query: 212 ADLLIIFARNTTTN--------QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNV 263 AD+ +FA+ T+ +I F+V++ G+ K+G++ ++ V Sbjct: 188 ADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGV 247 Query: 264 FVPDEDRLPGVNS-FQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAA 322 VP E+ L V S F+ +L R +A G GI + R QFG + Sbjct: 248 RVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHN 307 Query: 323 FQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMT-PGQASLGKAWISSKARETASLGRE 381 F L Q+KL +M+ M + + + G +A++ K + S A + + Sbjct: 308 FGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQ 367 Query: 382 LLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVT--------GREVTGIAS 427 ++GG G + + V + DL +EGT DI L G+E++G+ S Sbjct: 368 IMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 421 >5JSC-A nrPDB Length = 410 Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 83/295 (28%), Positives = 136/295 (46%), Gaps = 8/295 (2%) Query: 133 STFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK 192 + F L LG I+L G+ QK +YLP +A +A +AL+EP+ GSD + + +A + Sbjct: 105 ADFALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSARE 164 Query: 193 VEGGWKINGQKRWIGNSTFADLLIIFARNTT---TNQINGFIVKKDAPGLKATKIPNKIG 249 + ++G K WI N AD ++FAR I+ F+V D PGL+ + + I Sbjct: 165 DGDAYVLDGDKTWISNGGIADFYVVFARTGEAPGARGISAFVVDADTPGLEIAERIDVIA 224 Query: 250 LRMVQNGDILLQNVFVPDEDRL--PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCH 307 + + VP L PG F+ + L + R VA +G + Sbjct: 225 PHPLAR--LHFAGARVPRSQMLGAPG-EGFKLAMRTLDIFRTSVAAASLGFARHAMAEGV 281 Query: 308 RYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAW 367 RK FG L FQL Q KL QM + + L+ +R L + G+ +A++ K Sbjct: 282 ARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKWH 341 Query: 368 ISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 S A++ +L GG G+ + V + ++ + YEG ++ L+ GR++ Sbjct: 342 ASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGRDL 396 >3NF4-A nrPDB Length = 387 Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 104/377 (27%), Positives = 164/377 (43%), Gaps = 8/377 (2%) Query: 53 DLLTPEEQAIR--KKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAG-GSIKGYG 109 D L P ++A + RE +K + PI+ + + +P + +LGA G+ + +G Sbjct: 12 DRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWG 71 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 G EIA AS + + VHS L + + G+E QK+++LP + + Sbjct: 72 GGGQPYEVYLQVLEEIAARWASVAVAVSVHS-LSSHPLLVFGTEEQKKRWLPGMLSGEQI 130 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ-IN 228 ++L+EP GSDA+ L AT +GG+ ING K WI + AD +FAR ++ ++ Sbjct: 131 GAYSLSEPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFYTLFARTGEGSRGVS 190 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV--NSFQDTSKVLAV 286 F+V D PGL K K+GL V N + D DR G Q L Sbjct: 191 CFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARI-DADRRIGEEGQGLQIAFSALDS 249 Query: 287 SRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWR 346 R+ +A G++ D Y ER FG + Q L M V Sbjct: 250 GRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATARATYLD 309 Query: 347 LCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYT 406 + + G+ QAS+ K + A + + ++ GG G D+ V + + + + Sbjct: 310 AARRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQI 369 Query: 407 YEGTYDINTLVTGREVT 423 +EGT I LV R +T Sbjct: 370 FEGTNQIQRLVIARGLT 386 >4IRN-A nrPDB Length = 416 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 87/280 (31%), Positives = 135/280 (48%), Gaps = 16/280 (5%) Query: 151 GSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNST 210 G+E QKEKYLP L + +A A TEP GSD L TTA K + +NG K ++ N T Sbjct: 139 GTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKDGDKYILNGYKHYVTNGT 198 Query: 211 FADLLIIFAR---NTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPD 267 ADL IIFA + + F+++KD PGL +K +K+G+R + ++ L+N V Sbjct: 199 IADLFIIFATIDPSLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEVSA 258 Query: 268 EDRL----PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAF 323 +RL G+ F + + R + +G + + RY + KQFG + F Sbjct: 259 ANRLGEEGTGLAIFNHS---MEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKF 315 Query: 324 QLNQQKLVQM---LGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGR 380 QL KLV+M L N +A +++ + E QM +AS+ +IS ++ Sbjct: 316 QLVANKLVEMKLRLENAKAYL---YKVAWMKENKQMALLEASMANLYISEAWVQSCLEAI 372 Query: 381 ELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 E+ G G L + + + D Y GT +I +V + Sbjct: 373 EIHGAYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAK 412 >1RX0-A nrPDB Length = 393 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 95/373 (25%), Positives = 166/373 (44%), Gaps = 6/373 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGL 113 L E++ +K + +E+AP M E+ +K FP + K +G G I+ G GL Sbjct: 19 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 78 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 S ++ +A S + +I +H+ + + G+E Q+ K+ P L + A + Sbjct: 79 SRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSF-GNEEQRHKFCPPLCTMEKFASYC 137 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT--TTNQINGFI 231 LTEP +GSDA+ L T+A K + +NG K +I + +D+ ++ R I+ + Sbjct: 138 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 197 Query: 232 VKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLAVSRVM 290 V+K PGL K K+G ++ ++ VP +R+ F + L R+ Sbjct: 198 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 257 Query: 291 VAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC-K 349 +A +G + + +L RKQFG PLA+ Q Q L M + A LM Sbjct: 258 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 317 Query: 350 LYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEG 409 L E + S+ K + + + + ++ GG G L D+ V + D EG Sbjct: 318 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 377 Query: 410 TYDINTLVTGREV 422 + ++ ++ R + Sbjct: 378 SNEVMRILISRSL 390 >6ES9-A nrPDB Length = 551 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 100/394 (25%), Positives = 171/394 (43%), Gaps = 37/394 (9%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEF-PFHITPKLGAMGVAGGSI-KGYGCPG 112 L + + IR + R E+ V P E+ K + P I +L +GV G +I + +G G Sbjct: 167 LDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLG 226 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 LS + + T E++R + + S + I G+EAQK K+LP LA ++ Sbjct: 227 LSKASMVVVTEELSRGYIGVGS-LGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTA 285 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR----NTTTNQIN 228 TEP+ GSD L T A + W + G K WI ++ ++ + AR T ++ Sbjct: 286 VFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLS 345 Query: 229 GFIVKKD---------APGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV--NSF 277 F+ +K+ PG+ +I +G R ++ ++ + E+ L G F Sbjct: 346 MFLAEKEPGTDDDPFPTPGMTGGEI-EVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGF 404 Query: 278 QDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNV 337 + + +R+ A + +G++ ++ RY +RKQFG L F KL M + Sbjct: 405 KQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEI 464 Query: 338 ----QAMFLMGW-----RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGI 388 Q + W R C L G A L A ++ A + A ++ GGNG Sbjct: 465 MIARQLTYFSAWEKDHGRRCDL------EAGMAKLLGARVAWAAADNAL---QIHGGNGF 515 Query: 389 LADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 ++ +++ CD + +EG +I V R + Sbjct: 516 ALEYAISRVLCDARILNIFEGAAEIQAQVIARRL 549 >5ZW7-A nrPDB Length = 402 Score = 111 bits (277), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 89/354 (25%), Positives = 157/354 (44%), Gaps = 23/354 (6%) Query: 79 TEYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGLSITANAIATAEIAR--VDASCSTF 135 TE W+KA A G A G + +G L A+ + + D S Sbjct: 39 TELWKKA----------AAYGFAHGPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFS 88 Query: 136 ILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEG 195 + H ++ + GS K+KYL SL +A A TEPD GSD + TA EG Sbjct: 89 LCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEG 148 Query: 196 GWKINGQKRWIGNSTFADLLIIFARNTTTN---QINGFIVKKDAPGLKATKIPNKIGLRM 252 G+ +NG+K +I N+ AD+ II+A+ + ++ F+++K PGL ++ K L Sbjct: 149 GYILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVSAFLIEKGTPGLNVGEVIPKDCLSN 208 Query: 253 VQNGDILLQNVFVPDEDRL----PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHR 308 +I+ ++F+P R+ G F D+ + + ++ +G + + Sbjct: 209 CPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDS---MIWEKGCLSALFVGGLARLLETTLE 265 Query: 309 YLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWI 368 Y K R+QFG + FQ +++ M ++ LM +R C ++ GQ ++ K I Sbjct: 266 YAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLMLYRACWKHDQGQDAEADIAMSKLLI 325 Query: 369 SSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 S A ++ + GG + + + + ++ P + GT DI + R++ Sbjct: 326 SEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKL 379 >3R7K-A nrPDB Length = 403 Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 86/374 (22%), Positives = 166/374 (44%), Gaps = 9/374 (2%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFP--FHITP-KLGAMGVAGGSIKGYGCPG 112 TPE +A+ + R +E+E+AP + E+ E P H+ ++G +G+ G G G Sbjct: 30 TPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVG-GSGG 88 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYL-PSLAQLNTVAC 171 +I + + A +A ++ L + + IA GS+A E+Y+ P+LA + Sbjct: 89 NAIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLAG-KMIGS 147 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ--ING 229 +TEP GSD + L T A + + +NG K +I + AD + R ++ Sbjct: 148 LGVTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTGGPGYGGVSL 207 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSKVLAVSR 288 ++ K++PG + ++ +K+G R ++ +V VP ++ + NS F + R Sbjct: 208 LVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQQFQAER 267 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A Q + D+ + +ER+ FG PL Q+ + KL +M V + Sbjct: 268 LGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACTYTRAVM 327 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 + + G+ + S+ K + ++ GG G + + + + + D + Sbjct: 328 QRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRILGIGG 387 Query: 409 GTYDINTLVTGREV 422 GT +I V + + Sbjct: 388 GTNEIMNEVIAKRI 401 >4RM7-A nrPDB Length = 391 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 86/373 (23%), Positives = 156/373 (41%), Gaps = 11/373 (2%) Query: 53 DLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAE-FPFHITPKLGAMGVAG-GSIKGYGC 110 D L+ +EQ + VRE EK P W K + P + + G G I Sbjct: 6 DGLSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHRRNH 65 Query: 111 PGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVA 170 + A + E++R+ +C F + L + + S AQ + ++ Sbjct: 66 RTYDLFAQVLVIEELSRISGACLPF--QNDLLQLQILEAFASSAQTSPFRTEYQDTGRLS 123 Query: 171 -CWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN---- 225 A++EP+ GSD + T T+ +NG K ++ N +A L++ A + T + Sbjct: 124 YALAISEPEAGSDTRSMRTHVTREGDTLVMNGTKMFVNNGEYAPALLVSAYDKTGDDGEP 183 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSKVL 284 + + ++V + A G+ A KIG M+ + NV V + RL G + F +L Sbjct: 184 EFSFWMVPRSAAGIYAYP-EQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQLYSLL 242 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 RV +G + + + + R+ FG +A Q Q KL +M + M + Sbjct: 243 EYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTNMRNLV 302 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 + + Y+ G+ +L K ++ A E AS ++LGG G + + V+ + D Sbjct: 303 YGAAREYDRGEHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQDCRGY 362 Query: 405 YTYEGTYDINTLV 417 +GT ++ ++ Sbjct: 363 QFADGTDEVMVVI 375 >3P4T-A nrPDB Length = 403 Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 90/370 (24%), Positives = 148/370 (40%), Gaps = 14/370 (3%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKA-EFPFHITPKLGAMGVAGGSIKGYGCPGLS 114 T E +A+RK VR E+EV P E WE+A E P + K +G+ G Sbjct: 27 TAEREALRKTVRAFAEREVLPHAHE-WERAGEIPRELHRKAAELGLLGAGFPEDAGGSGG 85 Query: 115 ITANAIATAEIARVDASCSTFILVHSSLGMLTIAL-----CGSEAQKEKYLPSLAQLNTV 169 A+ + E S V++SL IA+ G + + Y+ + + Sbjct: 86 DGADPVVICEEMHYAGSPGG---VYASLFTCGIAVPHMIASGDQRLIDTYVRPTLRGEKI 142 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT--TTNQI 227 A+TEP GSD L T A + ING K +I + AD ++ AR + Sbjct: 143 GALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYITSGVRADYVVTAARTGGPGAGGV 202 Query: 228 NGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSKVLAV 286 + +V K PG + T+ +K+G R ++ +V VP + + N+ F + Sbjct: 203 SLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSENTGFAQIAAAFVA 262 Query: 287 SRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWR 346 RV +A Q + D+ + + R FG PL + Q Q L M + + Sbjct: 263 ERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGMARRIDVARVYTRH 322 Query: 347 LCKLYETGQMT-PGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 + + G+ + K A+ +L GG G +A+ V + + D+ + Sbjct: 323 VVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILG 382 Query: 406 TYEGTYDINT 415 GT +I T Sbjct: 383 IGGGTTEILT 392 >1R2J-A nrPDB Length = 366 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 108/252 (42%), Gaps = 12/252 (4%) Query: 80 EYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGLSITANAIATAEIARVDASCSTFILV 138 E+ E P + +LGA G+ + +G GL N TA + + CS+ V Sbjct: 18 EWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSL---CSSLRSV 74 Query: 139 HSSLGML--TIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG 196 +S GM T+ G Q+ +L L +A +E GSD S + T +++G Sbjct: 75 MTSQGMAAWTVQRLGDAGQRATFLKELTS-GKLAAVGFSERQAGSDLSAM-RTRVRLDGD 132 Query: 197 WKI-NGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQN 255 + +G K W + +AD L++F + +V D PG++ ++P G R + Sbjct: 133 TAVVDGHKVWTTAAAYADHLVVFGLQEDGSGAV-VVVPADTPGVRVERVPKPSGCRAAGH 191 Query: 256 GDILLQNVFVPDEDRLPGVNSFQD--TSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKER 313 D+ L V VP L G + + LA R VAW +GI + + R Sbjct: 192 ADLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAHARTR 251 Query: 314 KQFGAPLAAFQL 325 +QFG PL QL Sbjct: 252 EQFGRPLGDHQL 263 >5AHS-A nrPDB Length = 401 Score = 78.2 bits (191), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 83/307 (27%), Positives = 130/307 (42%), Gaps = 26/307 (8%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPGL 113 LTPE++ ++ + RE + A + ++P+ +L G G + G GL Sbjct: 4 LTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGL 63 Query: 114 SITANAIATAEIARVDASCSTF--ILVHSSLGML-TIALCGSEAQKEKYLPSLAQLNTVA 170 S I E+A+ +C+T I V S+LG + I GSE Q K L Sbjct: 64 STLDTVIVIEEMAK---ACATMGRITVDSNLGAIGAITKYGSEEQI-KLAADLVLAGDKP 119 Query: 171 CWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR---NTTTNQI 227 ++EP+ GS AS + T A K + +NG+K WI + L +IFAR + I Sbjct: 120 AICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGI 179 Query: 228 NGFIVKKDAPGLKATKIPNKI---GLRMVQNGDILLQNVFV--------PDEDRLPGVNS 276 FI D G + K+ ++ G+R + + ++ + PD + Sbjct: 180 GAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLK----RG 235 Query: 277 FQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGN 336 F RV +GI+ ++ YLK R+QFG PLA FQ Q + M Sbjct: 236 FAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQ 295 Query: 337 VQAMFLM 343 ++A LM Sbjct: 296 LEAARLM 302 >6CY8-B nrPDB Length = 380 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 59/223 (26%), Positives = 96/223 (43%), Gaps = 27/223 (12%) Query: 131 SCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTA 190 +CS IL H GSE K + LP LA +A A++E GSD S L TTA Sbjct: 93 ACSMPILEH-----------GSETLKHQLLPDLATGRKIAANAISEASAGSDISNLATTA 141 Query: 191 TKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQING------FIVKKDAPGLKATKI 244 K + +NG K ++ N + AD +++A TTN+ +G F+V ++ PG+ Sbjct: 142 QKEGDYYVLNGGKSYVTNGSIADYYVVYA---TTNKKHGYLGQTAFVVPRNTPGISVGND 198 Query: 245 PNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVS----RVMVAWQPIGISM 300 +K+GLR + N + + L +++ A S R + +G Sbjct: 199 YHKLGLRSAPLNQVFFDNCTIHKDYALGREGQ---GARIFAASMDWERCCLFAIFVGAMQ 255 Query: 301 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLM 343 + C Y R Q ++ FQ ++ M +++ LM Sbjct: 256 RDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLESARLM 298 >2FON-A nrPDB Length = 683 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 87/347 (25%), Positives = 138/347 (39%), Gaps = 69/347 (19%) Query: 135 FILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTAT--- 191 F +H + + I G++ Q+EK+LP ++ + C+A TE +GS+ GL TTAT Sbjct: 117 FTDLHWGMFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDP 176 Query: 192 ----KVEGGWKINGQKRWIGN----STFADLLIIFARNTTTNQ---INGFIVK------- 233 V + K W G ST A +++AR T + +NGFIV+ Sbjct: 177 QTDEFVIHSPTLTSSKWWPGGLGKVSTHA---VVYARLITDGKDYGVNGFIVQLRSLEDH 233 Query: 234 KDAPGLKATKIPNKIG---LRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSK-------- 282 K PG+ I K G + NG + +V +P + L V+ K Sbjct: 234 KPLPGVTVGDIGMKFGNGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPR 293 Query: 283 ------VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGA-------PLAAFQLNQQK 329 ++ V + +VA + +S + + RY R+QFG+ + ++ Q + Sbjct: 294 QLLYGTMVYVRQSIVADASLAMSRAVC-IATRYSAVRRQFGSQNGGQETQVIDYKTQQNR 352 Query: 330 LVQMLGNVQAMFLMGWRLCKLY----------------ETGQMTPGQASLGKAWISSKAR 373 L +L + A +G L LY E T G SL + + Sbjct: 353 LFPLLASAYAFRFVGEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIE 412 Query: 374 ETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 E R+L GG+G L + + F P TYEG + L R Sbjct: 413 EC----RKLCGGHGYLCSSGLPELFAVYVPACTYEGDNVVLQLQVAR 455 >4HR3-A nrPDB Length = 415 Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 70/284 (24%), Positives = 128/284 (45%), Gaps = 16/284 (5%) Query: 151 GSEAQKEKYLPSLAQLNTVACWALTEPD-NGSDASGLGTTATKVEGG-WKINGQKRWIGN 208 GS+ QKE +L L + + + + +TEPD SDA+ + TA VEG ING+K W Sbjct: 125 GSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAV-VEGDEVVINGRKWWSTG 183 Query: 209 STFADL-LIIFARNTTTN-----QINGFIVKKDAPGLKATKIPNKIGLRMVQNGD--ILL 260 D +IIF T N + + +V D PG+ ++ +G G + Sbjct: 184 VGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSF 243 Query: 261 QNVFVPDEDRLPGV-NSFQDTSKVLAVSRVMVAWQPIGIS-MGIYDMCHRYLKERKQFGA 318 NV +P + + G F+ L RV A + IG++ + + C R L +R FG Sbjct: 244 DNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGL-DRTAFGK 302 Query: 319 PLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSK--ARETA 376 PL N++++ + L+ L +T + +++ + +++ A++ Sbjct: 303 PLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVI 362 Query: 377 SLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 + ++ GG G+ DF +A A+ + + +G +++ V R Sbjct: 363 DMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVAR 406 >5GJ7-A nrPDB Length = 398 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 85/372 (22%), Positives = 158/372 (42%), Gaps = 41/372 (11%) Query: 59 EQAIRKKVRECME---------KEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GY 108 E A+ VRE + E AP E+ +FPF L A G ++ Y Sbjct: 10 EAALPADVRERLRITRDLAQAFHERAP---EHDRAGDFPFENIEDLKASGYVRWTVPVEY 66 Query: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQK------EKYLPS 162 G GLS+ + +A+ D S + I H + +L + G+ + E + Sbjct: 67 GGLGLSLEEMLMHQEVLAKGDGSTALAIGWHVGI-LLHLRETGAFPDELFRMVCESVVKE 125 Query: 163 LAQLNTVACWALTEPDNGSDASG--LGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR 220 A +N+ A TEP GS + G TTA KV GG++I G+K + S +++ A Sbjct: 126 GALINSCA----TEPATGSPSRGGKPETTAVKVPGGYRITGRKTFSTLSPALTWIMVTAT 181 Query: 221 NTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL----PGVNS 276 + + F+V+K+ ++ + + +G+R + DI+L++VFVP+E + PGV + Sbjct: 182 VADEDVVGQFLVRKE--DVEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQRPGVQA 239 Query: 277 FQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERK--QFGAPLAAFQLNQQKLVQML 334 + + + + +GI++ D Y + P+A +QKL +M Sbjct: 240 ERRPDGSGWLLHIPACY--LGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKLGEME 297 Query: 335 GNVQAMFLMGWRLCKLYETG---QMTPGQASLG--KAWISSKARETASLGRELLGGNGIL 389 + A + + L + ++ + Q G K ++ A + L ++GG + Sbjct: 298 LKLLAARTLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGGRSLS 357 Query: 390 ADFLVAKAFCDL 401 + + + D+ Sbjct: 358 RALPLERYYRDV 369 >5EZ3-A nrPDB Length = 573 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 62/279 (22%), Positives = 118/279 (42%), Gaps = 30/279 (10%) Query: 161 PSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG-WKINGQKRWIGNSTFADLLIIFA 219 P+ + +TE G+D T A GG W++ G K W ++ +D + A Sbjct: 200 PAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHK-WFMSAPMSDAFLTLA 258 Query: 220 RNTTTNQINGFIV-----KKDAPGLKATKIPNKIGLRMVQNGDI-----LLQNVFVPDED 269 + T ++ F++ K ++ G ++ +K+G R + ++ L Q + P E Sbjct: 259 Q--TKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGE- 315 Query: 270 RLPGVNSFQDTSKVLAVSRVMVAWQPIGI-SMGIYDMCHRYLKERKQFGAPLAAFQLNQQ 328 GV + D ++ ++R+ A G+ G+ + H + + R FG PL L Q+ Sbjct: 316 ---GVKTIMD---MVTLTRLDCAVASAGLMRSGLAEAVH-HSRHRHVFGKPLVEQPLMQR 368 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKA-------WISSKARETASLGRE 381 L M +V + RL + ++ +A+ ++ W+ A E Sbjct: 369 VLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAME 428 Query: 382 LLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 LGGNG + D +A+A+ + +EG+ ++ L R Sbjct: 429 CLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVAR 467 >4JEK-A nrPDB Length = 453 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 54/200 (27%), Positives = 84/200 (42%), Gaps = 15/200 (7%) Query: 124 EIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDA 183 EIA D S H + + I L GS+ Q+E +AQ N A +E N S Sbjct: 118 EIAAADGSLGHLFGYHLTNAPM-IELIGSQEQEEHLYTQIAQNNWWTGNASSE--NNSHV 174 Query: 184 SGLGTTATKVE-GGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKAT 242 +AT E GG+ +NG K + + +DLL +F + G I+ P +A Sbjct: 175 LDWKVSATPTEDGGYVLNGTKHFCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRAG 234 Query: 243 KIPNK----IGLRMVQNGDILLQNVFVPDEDRLPGVNSF-------QDTSKVLAVSRVMV 291 PN IG+R +G NV V ++ L N+F + S +++++ Sbjct: 235 VTPNDDWAAIGMRQTDSGSTDFHNVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIF 294 Query: 292 AWQPIGISMGIYDMCHRYLK 311 A +GI+ G D Y + Sbjct: 295 ANVYLGIAHGALDAAREYTR 314 >4X28-A nrPDB Length = 400 Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 87/355 (24%), Positives = 142/355 (40%), Gaps = 40/355 (11%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHI----TPKLGAMGVAG----GSIKG 107 TP+++ +R+++R + P E + + + + MG G G K Sbjct: 6 TPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPKE 65 Query: 108 YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 YG G S I T E A A F+ ++S TI G++ QK +LP +A + Sbjct: 66 YGGQGRSAMDQLIFTDEAAIAGAPVP-FLTINSV--APTIMAYGTDEQKRFFLPRIAAGD 122 Query: 168 TVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ- 226 +EP G+D + L TTA + + +NGQK W +AD + + R + Sbjct: 123 LHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSG 182 Query: 227 ------INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQD 279 I+ IV A G T + G +V VP +R+ N+ ++ Sbjct: 183 AKKHRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEENAGWKL 239 Query: 280 TSKVLAVSRV-MVAWQPIGISMGIYDMCHRYLKERKQF-----GAPLAAFQLNQQKLVQM 333 + L RV +V+ PI G C R ++E Q G L + Q L ++ Sbjct: 240 VTNQLNHERVALVSPAPI---FG----CLREVREWAQNTKDAGGTRLIDSEWVQLNLARV 292 Query: 334 LGNVQAMFLMGWRLCKLYETGQM----TPGQASLGKAWISSKARETASLGRELLG 384 + + L+ W L ++G +P AS K + + A E L E+LG Sbjct: 293 HAKAEVLKLINWELAS-SQSGPKDAGPSPADASAAKVFGTELATEAYRLLMEVLG 346 >2WBI-A nrPDB Length = 428 Score = 54.7 bits (130), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 73/296 (24%), Positives = 125/296 (42%), Gaps = 28/296 (9%) Query: 56 TPEEQAIRKKVRECMEKEVAPI---MTEYWEKAEFPFH------ITPKLGAMGVAGGSIK 106 T + Q + KV+ M++ + P +TE++ + E + KL M G Sbjct: 24 TRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGLWN 83 Query: 107 GY--GCPGLSITANAIATAEIARVDASCSTFILVHSSLG-MLTIALCGSEAQKEKYLPSL 163 + GLS A+ E + + F G M + L GSE QK+++L L Sbjct: 84 LFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPL 143 Query: 164 AQLNTVACWALTEPD-NGSDASGLGTTATKVEGGWKINGQKRW---IGNSTFADLLIIFA 219 Q N +C+ +TEPD SDA+ + + + E + ING+K W GN + I+ Sbjct: 144 LQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSGAGNPK-CKIAIVLG 202 Query: 220 RNTTTN-----QINGFIVKKDAPGLKATKIPNKIGLRMVQNG---DILLQNVFVPDEDRL 271 R T+ Q + +V + PG+K + + G +G +I V VP + + Sbjct: 203 RTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLI 262 Query: 272 PGV-NSFQDTSKVLAVSRVMVAWQPIGIS-MGIYDMCHRYLKERKQFGAPLAAFQL 325 G F+ + L R+ + +G++ + MC R +R F L A ++ Sbjct: 263 LGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCER-ATQRIAFKKKLYAHEV 317 >4Y9J-A nrPDB Length = 593 Score = 54.7 bits (130), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 67/279 (24%), Positives = 125/279 (44%), Gaps = 34/279 (12%) Query: 174 LTEPDNGSD-ASGLGTTATKVEGG-WKINGQKRWIGNSTFADLLIIFAR--NTTTNQING 229 +TE GSD A G T A +++ ++++G K W ++ AD+ + AR ++ N + G Sbjct: 190 MTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYK-WFSSAVDADVALTLARIVDSDGNALEG 248 Query: 230 ------FIVK-KDAPG----LKATKIPNKIGLRMVQNGDILLQNVF---VPDEDRLPGVN 275 F++K +D G ++ ++ NK+G + + ++LL + D+ R GV Sbjct: 249 SRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGR--GVA 306 Query: 276 SFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLG 335 S +L ++R+ A +G I + Y +R FG + + L+ L +M Sbjct: 307 GI---SNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEV 363 Query: 336 NVQAMFLMGW---RLCKLYETGQMTPGQASLG-------KAWISSKARETASLGRELLGG 385 + + L+ + RL L E G+ + +A + K + +A S G E GG Sbjct: 364 DTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGG 423 Query: 386 NGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTG 424 G + D + D + +EGT ++ +L R +G Sbjct: 424 QGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSG 462 >5YS9-A nrPDB Length = 708 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 88/356 (24%), Positives = 139/356 (39%), Gaps = 65/356 (18%) Query: 128 VDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQ--LNTVACWALTEPDNGSDASG 185 VD + VH+ L M I G++ Q + ++ A C+A+TE +GS+ +G Sbjct: 114 VDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHGSNVAG 173 Query: 186 LGTTATKVEGG--WKIN-----GQKRWIGNSTF-ADLLIIFARNTTTNQING---FIVK- 233 L TTAT ++ + IN K WIG + A FAR + G F+V+ Sbjct: 174 LETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVVQL 233 Query: 234 KDA------PGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKV---- 283 +D PG+ I K+G + NG I NV +P ++ L T KV Sbjct: 234 RDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPP 293 Query: 284 --------LAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFG-------APLAAFQLNQQ 328 L RV + +S + RY R+QFG + + +Q+ Sbjct: 294 LAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQR 353 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYETGQMT--------PGQASLGKAWISSKARETASLG- 379 +L+ +L AM + + Y+ Q T + +LGKA + K +S G Sbjct: 354 RLLPLLAFTYAMKMAADQSQIQYD--QTTDLLQTIDPKDKGALGKAIVDLKELFASSAGL 411 Query: 380 ---------------RELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 R+ GG+G +A+ D T+EG ++ L GR Sbjct: 412 KAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGR 467 >1W07-A nrPDB Length = 659 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 136/347 (39%), Gaps = 69/347 (19%) Query: 135 FILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK-- 192 ++ +H + + I G+E Q++K+L ++ + C+A TE +GS+ GL TTAT Sbjct: 98 YVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDP 157 Query: 193 -----VEGGWKINGQKRWIGN----STFADLLIIFARNTTTNQ---INGFIVKKDA---- 236 V K W G ST A +++AR T + I+GFIV+ + Sbjct: 158 KTDEFVIHTPTQTASKWWPGGLGKVSTHA---VVYARLITNGKDYGIHGFIVQLRSLEDH 214 Query: 237 ---PGLKATKIPNKIG---LRMVQNGDILLQNVFVPDEDRLPGVNSF--------QDTSK 282 P + I K+G + NG ++ +V +P + L ++ D K Sbjct: 215 SPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPK 274 Query: 283 VLA------VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGA-------PLAAFQLNQQK 329 L V + +VA +S + + RY R+QFGA + ++ Q + Sbjct: 275 QLVYGTMVYVRQTIVADASNALSRAVC-IATRYSAVRRQFGAHNGGIETQVIDYKTQQNR 333 Query: 330 LVQMLGNVQAMFLMGWRLCKLY----------------ETGQMTPGQASLGKAWISSKAR 373 L +L + A +G L LY E T G SL + Sbjct: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 Query: 374 ETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 E R+L GG+G L + + F P TYEG + L R Sbjct: 394 EC----RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 >5XDD-A nrPDB Length = 414 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 46/156 (29%), Positives = 69/156 (44%), Gaps = 13/156 (8%) Query: 121 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG 180 A AEIA DAS H S + L S QK ++ P + W L + Sbjct: 76 AIAEIASADASLGHLFGYHFS-NFAYVDLFASPEQKARWYPQAVRER----WFLGNASSE 130 Query: 181 SDASGLG--TTATKV-EGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVK---- 233 ++A L TAT + +G ++ING K + S AD L++FA + +G IV Sbjct: 131 NNAHVLDWRVTATPLPDGSYEINGTKAFCSGSADADRLLVFAVTSRDPNGDGRIVAALIP 190 Query: 234 KDAPGLKATKIPNKIGLRMVQNGDILLQNVFV-PDE 268 D G++ + +G+R +G + V V PDE Sbjct: 191 SDRAGVQVNGDWDSLGMRQTDSGSVTFSGVVVYPDE 226 >5Y9D-A nrPDB Length = 709 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 63/252 (25%), Positives = 101/252 (40%), Gaps = 39/252 (15%) Query: 128 VDASCSTFILVHSSLGMLTIALCGSEAQKEKYLP--SLAQLNTVACWALTEPDNGSDASG 185 VD S T + +H++L + +I G+ Q + ++ ++A C+A+TE +GS+ G Sbjct: 120 VDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKG 179 Query: 186 LGTTATKVEGGWK-------INGQKRWIGNST--------FADLLIIFARNTTTNQINGF 230 L TTAT + + I K WIG + FA L++ T N + Sbjct: 180 LETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPL 239 Query: 231 IVKKDAP---GLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKV---- 283 D G+ I K+G V NG I NV +P ++ L DT V Sbjct: 240 RNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPA 299 Query: 284 --------LAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAP-------LAAFQLNQQ 328 L RV + +S + RY R+QFG + + +Q+ Sbjct: 300 LDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQR 359 Query: 329 KLVQMLGNVQAM 340 +L+ +L AM Sbjct: 360 RLLPLLAYCYAM 371 >3MKH-A nrPDB Length = 438 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 79/341 (23%), Positives = 132/341 (38%), Gaps = 47/341 (13%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEK---AEFPFHITPKLGAMGVAGGSIKG---- 107 L+ ++ + R + P Y + + F T A V+ G +KG Sbjct: 7 LSASQKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGILKGQISP 66 Query: 108 -YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLA-Q 165 +G G ++ +AI E V+ S + I + LG+ I L E P L+ + Sbjct: 67 AHGGTGGTLIESAILVEECYSVEPSAALTIFA-TGLGLTPINLAAGPQHAEFLAPFLSGE 125 Query: 166 LNTVACWALTEPDNGSDA-----SGLGTTATKVEGG-WKINGQKRWIGNST-----FADL 214 + +A +EP ++A G TTA ++EG W ING+K W N DL Sbjct: 126 GSPLASLVFSEPGGVANALEKGAPGFQTTA-RLEGDEWVINGEKMWATNCAGWDFKGCDL 184 Query: 215 LIIFARNTTT---------NQINGFIVKK---DAPGLKATKIPNKI---GLRMVQNGDIL 259 + R+ TT N++ +V + D G + ++ + G V + Sbjct: 185 ACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTSVSGPHVR 244 Query: 260 LQNVFVPDEDRL-PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGA 318 NV VP ++ L P + S V+V +G+ +D ++ KE + GA Sbjct: 245 YTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKEDNRGGA 304 Query: 319 -PLAAFQLNQQKLVQMLGNV----QAMFLMGWRLCKLYETG 354 PL L +Q +L V +A + W+ E G Sbjct: 305 VPL----LERQAFADLLSGVKIQTEAARALTWKAAHAMENG 341 >2C12-A nrPDB Length = 439 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 8/103 (7%) Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSL--AQLNTVAC 171 S+ +I E+ V+ + S I V ++LG++ + LC S + +EK+L + +A Sbjct: 72 SLVHESIILEELFAVEPATSITI-VATALGLMPVILCDSPSLQEKFLKPFISGEGEPLAS 130 Query: 172 WALTEPDNGSD-----ASGLGTTATKVEGGWKINGQKRWIGNS 209 +EP+ ++ GL TTA KV W I+G+K W NS Sbjct: 131 LMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGEKLWPSNS 173 >4X28-D nrPDB Length = 373 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 49/211 (23%), Positives = 85/211 (40%), Gaps = 16/211 (7%) Query: 196 GWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQN 255 G+++ G + +G AD ++ A + + F+V PG+ T + GL V Sbjct: 142 GYRLTGTRTQVGYGPVADAFLVPAETDSGAAV--FLVAAGDPGVAVTALATT-GLGSV-- 196 Query: 256 GDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQ 315 G + L V R+ G + + +SR A+Q +G+ M Y + R+Q Sbjct: 197 GHLELNGAKVDAARRVGGTDVAVWLGTLSTLSRT--AFQ-LGVLERGLQMTAEYARTREQ 253 Query: 316 FGAPLAAFQLNQQKLVQMLGNVQAMFLM----GWRLCKLYETGQMTPGQASLGKA----W 367 F P+ +FQ Q+L +V+ + L WR+ + + P A + A W Sbjct: 254 FDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFW 313 Query: 368 ISSKARETASLGRELLGGNGILADFLVAKAF 398 + A + GG G+ D V + F Sbjct: 314 AAEAGHRVAHTIVHVHGGVGVDTDHPVHRYF 344 >1IS2-A nrPDB Length = 661 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 71/332 (21%), Positives = 119/332 (35%), Gaps = 49/332 (14%) Query: 138 VHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK----- 192 +H + + T+ + Q+E++ L +A TE +G+ GL TTAT Sbjct: 102 LHLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQ 161 Query: 193 --VEGGWKINGQKRWIGN-STFADLLIIFARNTTTNQ---INGFIV-------KKDAPGL 239 + + K W G ++ I+ A+ T + ++ F+V K PG+ Sbjct: 162 EFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGI 221 Query: 240 KATKIPNKIGLRMVQNGDILLQNVFVPDEDRL--------------PGVNSFQDTSKVLA 285 I K G + NG + + N +P E+ L P N + V Sbjct: 222 TVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFV 281 Query: 286 VSRVM-VAWQPIGISMGI---YDMCHRYLKERKQFGAP-LAAFQLNQQKLVQMLGNVQAM 340 S ++ A Q + + I Y R + ++ P + FQ Q KL +L A Sbjct: 282 RSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAF 341 Query: 341 FLMGWRLCKLYETGQMTPGQASLG------------KAWISSKARETASLGRELLGGNGI 388 +G + + Y + GQ L KA+ + A R GG+G Sbjct: 342 HFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGY 401 Query: 389 LADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 + + P T+EG + L T R Sbjct: 402 SHSSGIPNIYVTFTPACTFEGENTVMMLQTAR 433 >3M9V-A nrPDB Length = 439 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%) Query: 195 GGWKINGQKRWIGNSTFADLLIIFARNTTTN---QINGFIVKKDAPGLKATKIPNKIGLR 251 GGW ++G+K + + +I AR T+ ++ +V +D PG + +G+R Sbjct: 161 GGWLLSGRKTLVSMAPVGTHFVINARTDGTDGPPRLASPVVTRDTPGFTVLDNWDGLGMR 220 Query: 252 MVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLA---VSRVMVAWQPIGISMGIYDMCHR 308 DI+ + +P + L VLA VS V V +G++ YD Sbjct: 221 ASGTVDIVFDDCPIPADHVLMRDPVGARNDAVLAGQTVSSVSVLGVYVGVAQAAYDTAVA 280 Query: 309 YLKERKQ 315 L+ R + Sbjct: 281 ALERRPE 287 >5K3G-A nrPDB Length = 684 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 58/253 (22%), Positives = 93/253 (36%), Gaps = 41/253 (16%) Query: 151 GSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGW-------KINGQK 203 S+ Q+ K+L + + +A TE +G++ L TTAT G KI K Sbjct: 128 ASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIGTQEFVLHTPKITALK 187 Query: 204 RWIGN----STFADLLII-------FARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRM 252 W GN S +A ++ F +T + K PG+ I K+ + Sbjct: 188 WWPGNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLPGITIGDIGPKMAYNI 247 Query: 253 VQNGDILLQNVFVPDEDRLPGVNSFQ-------------DTSKVLAVSRVMVAWQPIGIS 299 V NG + N +P + L + + S ++ V M+ Q I +S Sbjct: 248 VDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYSAMVHVRSYMLTGQAIMLS 307 Query: 300 MGIYDMCHRYLKERKQFG-------APLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYE 352 + ++ RY R+Q + +Q Q +L + A G KLYE Sbjct: 308 YAL-NIATRYSAVRRQGQIDKNEPEVKVLEYQTQQHRLFPFIARAYAFQFAGAETVKLYE 366 Query: 353 T--GQMTPGQASL 363 +M G SL Sbjct: 367 RVLKEMKSGNVSL 379 >5K3J-A nrPDB Length = 674 Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 30/54 (55%) Query: 138 VHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTAT 191 +H +L + T+ S+ Q+EK+L + + C+A TE +GS+ L TTA Sbjct: 113 LHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLETTAV 166 >4XVX-A nrPDB Length = 389 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 55/236 (23%), Positives = 97/236 (41%), Gaps = 25/236 (10%) Query: 169 VACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT----TT 224 V C +E GSD + T +GG+++ G K+++ S AD +++ AR+ T+ Sbjct: 118 VLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTS 177 Query: 225 NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSKV 283 N +V A + K+G + + + + +VP + + + S Sbjct: 178 RHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCI-DTWVPADALVARAGTGLAAISWG 236 Query: 284 LAVSRVMVAWQ-------PIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGN 336 LA R+ +A Q IGI++ + R+QFG L Q L + + Sbjct: 237 LAHERMSIAGQIAASCQRAIGITLA-------RMMSRRQFGQTL----FEHQALRLRMAD 285 Query: 337 VQAMF-LMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILAD 391 +QA L+ + L + E G++ A+ K + E S + GG G L D Sbjct: 286 LQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVD 341 >5UR2-A nrPDB Length = 984 Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 24/113 (21%) Query: 303 YDMCHRYLKERKQFGAP---------LAAFQLNQQKL--------VQMLGNV-----QAM 340 Y++C +YL E +F P LAA L +KL QML + + + Sbjct: 334 YELCAKYLLENIKFIRPAFASHNVRTLAACMLYAEKLNIPKEALEFQMLYGMAEPIKKTI 393 Query: 341 FLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFL 393 MG+R+ + G++ PG A L + + + + E+ G+ N +A+ L Sbjct: 394 VDMGYRMREYAPVGELIPGMAYLVRRLLENTSNESWLRGK--FADNKSMAELL 444 >5LVW-A nrPDB Length = 413 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/87 (21%), Positives = 38/87 (43%), Gaps = 2/87 (2%) Query: 189 TATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN--QINGFIVKKDAPGLKATKIPN 246 TA + GG+++ G + D I+ AR + + G + A L + Sbjct: 144 TAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWH 203 Query: 247 KIGLRMVQNGDILLQNVFVPDEDRLPG 273 +G+R + ++L++ FVP+ + G Sbjct: 204 TVGMRATGSHTVVLRDTFVPEHRVISG 230 >2RFQ-A nrPDB Length = 394 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/78 (21%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 193 VEGGWKINGQKRWIGNSTFADLLI----IFARNTTTNQINGFIVKKDAPGLKATKIPNKI 248 V+GG+ +NG W A + + + ++ I ++D + + N + Sbjct: 129 VDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVDFVSFLIPRED---YRIDDVWNVV 185 Query: 249 GLRMVQNGDILLQNVFVP 266 GLR + +++++VFVP Sbjct: 186 GLRGTGSNTVVVEDVFVP 203 >5JIP-A nrPDB Length = 332 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Query: 221 NTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQN--GDILLQNVFVPDEDRLPGVNSFQ 278 N N I+ + GL A NKI + N D+ NVFV D G + Sbjct: 220 NWGPNSIDSLMPPSAVTGLNAYISGNKIFVNWTANKEDDLNGYNVFV--NDNYAGTLPRK 277 Query: 279 DTSKVLAVSRVMV-AWQPIGISMGIYDMCHRYLKERKQF 316 T V+ SR + +PI IS+ +D+ + KER ++ Sbjct: 278 ATKIVIDKSRFYLPKGKPIKISIEAFDITGDFSKERTEY 316 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2IX5-A nrPDB 585 e-167 4N5F-A nrPDB 477 e-135 5LNX-A nrPDB 473 e-134 1JQI-A nrPDB 467 e-132 5OL2-C nrPDB 467 e-132 4L1F-A nrPDB 465 e-131 4U83-A nrPDB 459 e-130 2VIG-A nrPDB 456 e-129 4M9A-A nrPDB 455 e-128 1UKW-A nrPDB 450 e-127 3GNC-A nrPDB 449 e-126 3MDE-A nrPDB 442 e-124 6FAH-C nrPDB 441 e-124 2A1T-A nrPDB 440 e-124 3SF6-A nrPDB 439 e-123 1BUC-A nrPDB 435 e-122 4O5M-A nrPDB 435 e-122 1SIR-A nrPDB 434 e-122 1IVH-A nrPDB 434 e-122 2EBA-A nrPDB 430 e-121 3SWO-A nrPDB 427 e-120 4KTO-A nrPDB 423 e-119 3PFD-A nrPDB 422 e-118 2JIF-A nrPDB 421 e-118 4W9U-A nrPDB 416 e-116 2DVL-A nrPDB 414 e-116 2PG0-A nrPDB 408 e-114 1RX0-A nrPDB 407 e-114 4IV6-A nrPDB 403 e-113 3NF4-A nrPDB 390 e-109 2CX9-A nrPDB 384 e-107 3MPI-A nrPDB 383 e-106 3OWA-A nrPDB 380 e-106 2Z1Q-A nrPDB 379 e-105 3B96-A nrPDB 364 e-101 3R7K-A nrPDB 361 e-100 6ES9-A nrPDB 359 2e-99 4IRN-A nrPDB 355 2e-98 5ZW7-A nrPDB 345 2e-95 3P4T-A nrPDB 341 4e-94 5IDU-A nrPDB 336 1e-92 5JSC-A nrPDB 315 3e-86 5AHS-A nrPDB 314 7e-86 6CY8-B nrPDB 312 2e-85 4RM7-A nrPDB 305 2e-83 2WBI-A nrPDB 281 3e-76 4HR3-A nrPDB 269 1e-72 4X28-A nrPDB 252 3e-67 1R2J-A nrPDB 247 7e-66 5YS9-A nrPDB 247 7e-66 5Y9D-A nrPDB 243 1e-64 5GJ7-A nrPDB 241 5e-64 2FON-A nrPDB 227 9e-60 1W07-A nrPDB 226 2e-59 5EZ3-A nrPDB 217 7e-57 3MKH-A nrPDB 214 7e-56 4Y9J-A nrPDB 202 2e-52 2C12-A nrPDB 188 5e-48 4X28-D nrPDB 186 1e-47 4JEK-A nrPDB 174 6e-44 5XDD-A nrPDB 167 7e-42 Sequences not found previously or not previously below threshold: 3U33-A nrPDB 187 6e-48 1IS2-A nrPDB 169 2e-42 5K3G-A nrPDB 160 9e-40 5K3J-A nrPDB 159 3e-39 4ZYJ-A nrPDB 147 8e-36 4XVX-A nrPDB 142 3e-34 3M9V-A nrPDB 139 2e-33 3MXL-A nrPDB 138 5e-33 2RFQ-A nrPDB 96 2e-20 2JBS-A nrPDB 88 5e-18 3AFF-A nrPDB 84 1e-16 5LVW-A nrPDB 80 2e-15 2OR0-A nrPDB 70 1e-12 3HWC-A nrPDB 40 0.002 4G5E-A nrPDB 37 0.016 2YYI-A nrPDB 36 0.023 4XGC-A nrPDB 34 0.15 4Q0M-A nrPDB 33 0.31 1U8V-A nrPDB 31 0.68 5VA1-A nrPDB 31 1.2 1KA4-A nrPDB 31 1.3 4HNL-A nrPDB 30 1.6 2Q3R-A nrPDB 30 1.8 6B1B-A nrPDB 30 2.4 1ICQ-A nrPDB 30 2.9 3RMT-A nrPDB 30 3.1 5K1Q-A nrPDB 29 4.7 1G29-1 nrPDB 29 4.8 5LC3-A nrPDB 29 5.0 5LC2-A nrPDB 28 5.6 1G21-E nrPDB 28 6.2 6NFE-A nrPDB 28 6.3 >2IX5-A nrPDB Length = 436 Score = 585 bits (1508), Expect = e-167, Method: Composition-based stats. Identities = 436/436 (100%), Positives = 436/436 (100%) Query: 1 MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQ 60 MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQ Sbjct: 1 MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQ 60 Query: 61 AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAI 120 AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAI Sbjct: 61 AIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAI 120 Query: 121 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG 180 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG Sbjct: 121 ATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNG 180 Query: 181 SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLK 240 SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLK Sbjct: 181 SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLK 240 Query: 241 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM 300 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM Sbjct: 241 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISM 300 Query: 301 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ 360 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ Sbjct: 301 GIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ 360 Query: 361 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR Sbjct: 361 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 Query: 421 EVTGIASFKPATRSRL 436 EVTGIASFKPATRSRL Sbjct: 421 EVTGIASFKPATRSRL 436 >4N5F-A nrPDB Length = 385 Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats. Identities = 115/377 (30%), Positives = 181/377 (48%), Gaps = 5/377 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYG 109 ++L T +++ IR R + +AP ++ A P I +LG +G+ G + G Sbjct: 9 MDELYTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELG 68 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 A A+A E+A DA+C+T + VH+S+G I G+ AQK+++L +A + Sbjct: 69 GSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVI 128 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQ 226 + LTEP GS+A+ L T A +G W +NG K+++ N A + I+FA Sbjct: 129 GAFCLTEPHAGSEANNLRTRAELRDGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEAGKRG 188 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP-GVNSFQDTSKVLA 285 I+ F+V D PG K K+G+R I +N +P+++ L + L Sbjct: 189 ISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALSNLE 248 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 R+ +A Q +GI+ +D RY ER QFG P+A Q QQKL M + A L+ Sbjct: 249 GGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLLVH 308 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 KL G +AS K + S A S ++ GG G L D+ V + + D Sbjct: 309 HAAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARITQ 368 Query: 406 TYEGTYDINTLVTGREV 422 YEGT ++ +V R++ Sbjct: 369 IYEGTSEVQRMVIARQL 385 >5LNX-A nrPDB Length = 379 Score = 473 bits (1217), Expect = e-134, Method: Composition-based stats. Identities = 123/374 (32%), Positives = 187/374 (50%), Gaps = 5/374 (1%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGLS 114 T E+ +RK VR+ KE+AP + EFPF + K+G G+ G + YG G Sbjct: 4 TQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAGAD 63 Query: 115 ITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWAL 174 + + +A EI+R+ A+ + VH+S+G I G+E QK KY+P+LA + + +AL Sbjct: 64 VVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAFAL 123 Query: 175 TEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQINGFI 231 TEP +GSDA L TTA K G + +NG K +I N AD+ I FA + I+ FI Sbjct: 124 TEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGISAFI 183 Query: 232 VKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSRVM 290 V+K+ PG K K+GL +++ N VP+ + L F L V R+ Sbjct: 184 VEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVGRIG 243 Query: 291 VAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKL 350 +A Q +GI+ + Y K+R QFG P+AA Q KL M +A + + L Sbjct: 244 IAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHAADL 303 Query: 351 YETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGT 410 + G +AS+ K + S A + A ++ GG G + D+ V + D + YEGT Sbjct: 304 HNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYEGT 363 Query: 411 YDINTLVTGREVTG 424 +I L+ + + G Sbjct: 364 NEIQRLIISKYLLG 377 >1JQI-A nrPDB Length = 388 Score = 467 bits (1202), Expect = e-132, Method: Composition-based stats. Identities = 108/375 (28%), Positives = 179/375 (47%), Gaps = 5/375 (1%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPG 112 L Q +R+ R+ EKE+ PI + ++ FP K+G +G+ + + G Sbjct: 9 ELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAG 68 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 L A +IA EI+R AS + V++SL + I GS QK++++ + + C+ Sbjct: 69 LDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCF 128 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN---QING 229 AL+EP NGSDA TTA + W +NG K WI NS A ++FA + I+ Sbjct: 129 ALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISA 188 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSR 288 F+V PGL K +K+G+R +++ ++ +P E+ L F+ + L + R Sbjct: 189 FLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGR 248 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A Q +GI+ D +Y + R FGAPL Q Q KL M +++ L+ WR Sbjct: 249 IGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWRAA 308 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L + + ++++ K S A + ++LGG G + + + + D YE Sbjct: 309 MLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYE 368 Query: 409 GTYDINTLVTGREVT 423 GT +I LV + Sbjct: 369 GTSEIQRLVIAGHLL 383 >5OL2-C nrPDB Length = 378 Score = 467 bits (1202), Expect = e-132, Method: Composition-based stats. Identities = 110/376 (29%), Positives = 181/376 (48%), Gaps = 5/376 (1%) Query: 53 DLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAG-GSIKGYGCP 111 DL + + Q +++ E EV P+ TE E+ FP+ K+ G+ G K YG Sbjct: 2 DLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGE 61 Query: 112 GLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVAC 171 G +A E++RV + + H+SLG I G+E QK+K+L LA + Sbjct: 62 GGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGA 121 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT---TTNQIN 228 + LTEP+ G+DASG TTA + +NG K +I N+ D+ ++ A I+ Sbjct: 122 FGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAIAGDIYVVMAMTDKSKGNKGIS 181 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVS 287 FIV+K PG K+G+R +++ ++ +P E+ L F+ L Sbjct: 182 AFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDGG 241 Query: 288 RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRL 347 R+ +A Q +G++ G D +Y+KER QFG PL+ FQ Q +L M VQA + ++ Sbjct: 242 RIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQA 301 Query: 348 CKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTY 407 + G+ +A++ K + + A E + +L GG G D+ V + D + Y Sbjct: 302 AINKDLGKPYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIY 361 Query: 408 EGTYDINTLVTGREVT 423 EGT ++ +V ++ Sbjct: 362 EGTSEVQRMVISGKLL 377 >4L1F-A nrPDB Length = 383 Score = 465 bits (1197), Expect = e-131, Method: Composition-based stats. Identities = 107/378 (28%), Positives = 180/378 (47%), Gaps = 5/378 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS-IKGYG 109 + LT ++Q I+ E EK +AP + E + + + K+G G G + YG Sbjct: 1 MDFNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 GL + + +A E+++VD + + SL I + G+E QK+KYL +A+ V Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQ 226 + LTEP G+DAS TTA + +NG K +I N AD ++FA + + Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVLKGDKYILNGSKIFITNGKEADTYVVFAMTDKSQGVHG 180 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLA 285 I+ FI++K PG + KI +K+G +++ ++ VP E+ L F+ + L Sbjct: 181 ISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAMETLD 240 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 R+ VA Q +GI+ G +Y KER+QFG ++ FQ Q + M ++A + + Sbjct: 241 GGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARYLVY 300 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 L G+ A++ K + S A E + ++ GG G D+ + + + Sbjct: 301 HAAMLKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAKITQ 360 Query: 406 TYEGTYDINTLVTGREVT 423 YEGT + +VT R + Sbjct: 361 IYEGTNQVMRIVTSRALL 378 >4U83-A nrPDB Length = 382 Score = 459 bits (1182), Expect = e-130, Method: Composition-based stats. Identities = 114/374 (30%), Positives = 182/374 (48%), Gaps = 5/374 (1%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS-IKGYGCPG 112 LLT ++ IR+ R+ ++ +AP + FP ++GA+G G + +G Sbjct: 9 LLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGSD 68 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 L + A A+A EIA D +CST + VHSS+G + I G+E QK ++LP +A + + Sbjct: 69 LDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGF 128 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTT---TNQING 229 ALTEP GSDAS L T A + I+G K++I + +++I+FA I+ Sbjct: 129 ALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGISA 188 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSR 288 FIV D PG + + +K+G + N+ VP E+RL ++ L R Sbjct: 189 FIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGGR 248 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A Q +G++ ++ Y +ER FG P+ Q +L M ++ M Sbjct: 249 IGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAA 308 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L E G+ +AS+ K S A + S ++ GG G LAD+ V + + D+ YE Sbjct: 309 ALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQIYE 368 Query: 409 GTYDINTLVTGREV 422 GT D+ LV R + Sbjct: 369 GTSDVQRLVIARGL 382 >2VIG-A nrPDB Length = 391 Score = 456 bits (1174), Expect = e-129, Method: Composition-based stats. Identities = 110/383 (28%), Positives = 181/383 (47%), Gaps = 7/383 (1%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCPG 112 L Q + + R+ EKE+ PI + ++ FP K+G +G+ + + G G Sbjct: 5 ELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAG 64 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 L A AIA EI+R AS + V++SL + I GS+ QK+ ++ + + C+ Sbjct: 65 LDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCF 124 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTT---TNQING 229 AL+EP NGSDA TTA W +NG K WI N+ A ++FA I+ Sbjct: 125 ALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSISA 184 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSR 288 F+V PGL K +K+G+R +++ ++ +P + L F+ + L + R Sbjct: 185 FLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGR 244 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + +A Q +GI+ D Y + R FGAPL Q+ Q KL M +++ L+ WR Sbjct: 245 IGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAA 304 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L + + +A++ K S A + ++LGG G + + + + D YE Sbjct: 305 MLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYE 364 Query: 409 GTYDINTLVTGREVTGIASFKPA 431 GT +I LV + + S++ A Sbjct: 365 GTSEIQRLVIAGHL--LRSYRSA 385 >4M9A-A nrPDB Length = 385 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 114/377 (30%), Positives = 179/377 (47%), Gaps = 5/377 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYG 109 +DL T +++ I R + +AP ++ ++ P + ++G +G G + +G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 A A+A EIA ASC+T + VH+S+G + G+ QKE++L LA TV Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQ 226 ++LTEP GS+A L T A +G W +NG K+++ N A L I+FA Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELRDGKWILNGSKQFVTNGARAGLAIVFAMTDPDEGKRG 188 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP-GVNSFQDTSKVLA 285 ++ F+V D PG K K+G+R I L+N +P E+ L + L Sbjct: 189 LSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSNLE 248 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 R+ +A Q GI+ +D RY +ER QFG P+A Q +KL M + A L+ Sbjct: 249 GGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLLTH 308 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 +L G +AS K + S A S ++ GG G L D+ V + + D Sbjct: 309 HAARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARITQ 368 Query: 406 TYEGTYDINTLVTGREV 422 YEGT ++ +V R++ Sbjct: 369 IYEGTSEVQRMVIARQL 385 >1UKW-A nrPDB Length = 379 Score = 450 bits (1158), Expect = e-127, Method: Composition-based stats. Identities = 118/378 (31%), Positives = 192/378 (50%), Gaps = 6/378 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYG 109 + LT E++ ++ R ++ + P+ EY EK E P+ + KL +G+ I + YG Sbjct: 1 IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYG 60 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 GL + I E+A T I + S LG+ + L G+E QKE++L L + + Sbjct: 61 GMGLKMLDEVIVGEELAYACMGIYT-IPMASDLGITPVLLAGTEEQKERFLRPLTEKPAL 119 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQ 226 A +AL+EP NGSDA+ L T A + + +NG K WI N A+ +++FA Sbjct: 120 AAFALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRHKG 179 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLA 285 + +V++ PG KA KI K+G R +++ ++V VP E+RL F+ + L Sbjct: 180 VVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLN 239 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 +R+ VA +G++ D +Y KER+ FG P+A FQ Q KLV ML ++ + + Sbjct: 240 KTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTY 299 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 L + G +++ KA+ S A E A+ ++ GG G + +F V K D++ Sbjct: 300 YAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQ 359 Query: 406 TYEGTYDINTLVTGREVT 423 YEGT +I L+ R + Sbjct: 360 IYEGTNEIQRLIIARHIL 377 >3GNC-A nrPDB Length = 399 Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats. Identities = 146/399 (36%), Positives = 219/399 (54%), Gaps = 5/399 (1%) Query: 33 PQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHIT 92 P + A+TF D + L +E+ +R + ++AP +TE + I Sbjct: 2 PGSMAAATFH--WDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIF 59 Query: 93 PKLGAMGVAGGSIKG-YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCG 151 ++G +G+ G +I YG PGL + + E+ RVD+ + + V SSL M+ I G Sbjct: 60 REMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFG 119 Query: 152 SEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTF 211 S+AQKEKYLP LA + C+ LTEP++GSD + T A KV GG+ ++G K WI NS Sbjct: 120 SDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGGYSLSGSKMWITNSPI 179 Query: 212 ADLLIIFARNTTT--NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDED 269 AD+ +++A+ ++I GFI++K GL A I K+GLR G+I+L FVP+E+ Sbjct: 180 ADVFVVWAKLDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEEN 239 Query: 270 RLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQK 329 LP V + L +R +AW +G + + + +Y+ +RKQFG PLAA QL Q+K Sbjct: 240 ILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKK 299 Query: 330 LVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGIL 389 L M + RL ++ + G S+ K KA + A L R++LGGNGI Sbjct: 300 LADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGIS 359 Query: 390 ADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASF 428 +F VA+ +LE + TYEGT+DI+ L+ GR TGI +F Sbjct: 360 DEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAF 398 >3MDE-A nrPDB Length = 385 Score = 442 bits (1137), Expect = e-124, Method: Composition-based stats. Identities = 107/383 (27%), Positives = 175/383 (45%), Gaps = 9/383 (2%) Query: 50 HFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-Y 108 F+ LT +++ + R+ +E+ P+ EY E+P + + +G+ I + Sbjct: 1 GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESF 60 Query: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNT 168 G GL I + + T E+A T I ++ LG + + + G+ Q++KYL + + Sbjct: 61 GGLGLGIIDSCLITEELAYGCTGVQTAIEANT-LGQVPLIIGGNYQQQKKYLGRMTEEPL 119 Query: 169 VACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---- 224 + + +TEP GSD +G+ T A K + INGQK WI N A+ + AR+ Sbjct: 120 MCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAP 179 Query: 225 --NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTS 281 GFIV+ D PG++ + +G R I+ ++V VP E+ L G F+ Sbjct: 180 ASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAM 239 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 +R VA +G++ D +Y ERK FG LA Q L M V+ Sbjct: 240 GTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELAR 299 Query: 342 LMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 L R ++G+ AS+ KA+ + A + A+ ++ GGNG ++ V K D Sbjct: 300 LSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDA 359 Query: 402 EPIYTYEGTYDINTLVTGREVTG 424 + YEGT I ++ RE G Sbjct: 360 KIYQIYEGTAQIQRIIIAREHIG 382 >6FAH-C nrPDB Length = 379 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 118/371 (31%), Positives = 179/371 (48%), Gaps = 6/371 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVA-PIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPG 112 + + + IRK R+ EKE+ I+ E E EFP I K+ G G I G G Sbjct: 3 FSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSG 62 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 + I E ARV S ++ +SL + L G+E Q EKYL + + Sbjct: 63 GDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAF 122 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT---TTNQING 229 ALTEP GSDA G+ TTA + + +NG+K +I + D +I+A+ T I+ Sbjct: 123 ALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISA 182 Query: 230 FIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSR 288 FIV + G+ K +K+GL DI++++V VP E+RL VN F + K L V R Sbjct: 183 FIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGR 242 Query: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + VA Q IG++ G D +Y KERKQFG +A FQ + M ++A L+ + Sbjct: 243 LGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAA 302 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L + + +AS+ K + S E + ++ GG G + ++ V + + D YE Sbjct: 303 SLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYE 362 Query: 409 GTYDINTLVTG 419 GT + +V Sbjct: 363 GTSQVQQMVIS 373 >2A1T-A nrPDB Length = 421 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 106/383 (27%), Positives = 173/383 (45%), Gaps = 9/383 (2%) Query: 49 YHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGY 108 F+ T +++ + R+ +E+ P+ EY + E+P + + +G+ I Sbjct: 35 LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPEN 94 Query: 109 -GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 G GL + + E+A T I +SLG + I + G++ QK+KYL + + Sbjct: 95 CGGLGLGTFDACLISEELAYGCTGVQTAIEG-NSLGQMPIIIAGNDQQKKKYLGRMTEEP 153 Query: 168 TVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT--- 224 + + +TEP GSD +G+ T A K + INGQK WI N A+ + AR+ Sbjct: 154 LMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 Query: 225 ---NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPG-VNSFQDT 280 GFIV+ D PG++ + +G R I+ ++V VP E+ L G F+ Sbjct: 214 PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVA 273 Query: 281 SKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAM 340 +R +VA +G++ D +Y ERK FG L Q L +M V+ Sbjct: 274 MGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELA 333 Query: 341 FLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCD 400 + R ++G+ AS+ KA+ A + A+ ++LGGNG ++ V K D Sbjct: 334 RMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRD 393 Query: 401 LEPIYTYEGTYDINTLVTGREVT 423 + YEGT I L+ RE Sbjct: 394 AKIYQIYEGTSQIQRLIVAREHI 416 >3SF6-A nrPDB Length = 403 Score = 439 bits (1130), Expect = e-123, Method: Composition-based stats. Identities = 133/402 (33%), Positives = 212/402 (52%), Gaps = 3/402 (0%) Query: 29 SVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFP 88 S+ + D N +L+ EE+ IR VR +++ + P + ++E E P Sbjct: 4 SMTNSAVAQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGELP 63 Query: 89 -FHITPKLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTI 147 + +LG +G+ G +KGYGC G+S A +A E+ D+ + + V SL M I Sbjct: 64 ARELAVELGELGLLGMHLKGYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAI 123 Query: 148 ALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIG 207 GS+ QK+++LP +A + + C+ LTEPD+GSD +G+ T AT+ W + G K WI Sbjct: 124 HAFGSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATRSGDDWILTGTKMWIT 183 Query: 208 NSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPD 267 N + AD+ +++AR I GF+V D PG A I +K+ LR +++L V +PD Sbjct: 184 NGSVADVAVVWART--DEGIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPD 241 Query: 268 EDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQ 327 RLPG S + L +R + + +G + + Y R+QF P+ FQL Q Sbjct: 242 SARLPGATSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQLTQ 301 Query: 328 QKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNG 387 QKL M FL+ L + + G++ P Q SLGK +A E A R +LG +G Sbjct: 302 QKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLGKLNNVREAIEIARTARTVLGASG 361 Query: 388 ILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASFK 429 I ++ V + +LE + TYEGT +++TL+ G+ +TG+ +F+ Sbjct: 362 ITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQALTGVGAFR 403 >1BUC-A nrPDB Length = 383 Score = 435 bits (1120), Expect = e-122, Method: Composition-based stats. Identities = 112/382 (29%), Positives = 181/382 (47%), Gaps = 9/382 (2%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG--- 107 + LT +Q K + EK++AP +TE K + + +L ++G+ G + Sbjct: 1 MDFNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYG 60 Query: 108 -YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQL 166 G G + + +A E+A+ DA + + SL I G+EAQKEK+L L + Sbjct: 61 GSGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEG 120 Query: 167 NTVACWALTEPDNGSDASGLGTTATK-VEGGWKINGQKRWIGNSTFADLLIIFARNT--- 222 + + LTEP+ G+DASG T ATK +G + +NG K +I N AD+ I+FA Sbjct: 121 TKLGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTDKSK 180 Query: 223 TTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTS 281 + I FI++ PG K +K+G+ Q +++ Q+V VP E+ L F+ Sbjct: 181 GNHGITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAM 240 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 L R+ VA Q +GI+ Y K+R QFG PL FQ KL M ++A Sbjct: 241 MTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAAR 300 Query: 342 LMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 + ++ + G+ A++ K S A + ++ GG G ++ VA+ D Sbjct: 301 NLVYKAACKKQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDA 360 Query: 402 EPIYTYEGTYDINTLVTGREVT 423 + YEGT ++ +VTG + Sbjct: 361 KITQIYEGTNEVQLMVTGGALL 382 >4O5M-A nrPDB Length = 390 Score = 435 bits (1118), Expect = e-122, Method: Composition-based stats. Identities = 113/377 (29%), Positives = 175/377 (46%), Gaps = 5/377 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS-IKGYG 109 N L E +A+R VR E +AP+ E +FP H+ + G +GV G + + YG Sbjct: 9 MNFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYG 68 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 G+ A+ IA EI+R AS HS+L + I GS Q+ KYLP L V Sbjct: 69 GAGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHV 128 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT---TTNQ 226 A++EP GSD + A K + +NG K WI N AD+L+++A+ Sbjct: 129 GALAMSEPGAGSDVVSMKLAAEKRGDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGPRG 188 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP-GVNSFQDTSKVLA 285 I+ FI++K G + +K+G+R +++ ++ VP E+ L L Sbjct: 189 ISAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMSGLD 248 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 RV++A P+GI D+ Y+ ERKQF P+ FQL Q KL M A + Sbjct: 249 YERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAYVY 308 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 + + G+ T A+ + + A + A + LGGNG + D+ + D + Sbjct: 309 AVAAACDRGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKLYE 368 Query: 406 TYEGTYDINTLVTGREV 422 GT +I ++ GRE+ Sbjct: 369 IGAGTSEIRRMLIGREL 385 >1SIR-A nrPDB Length = 394 Score = 434 bits (1116), Expect = e-122, Method: Composition-based stats. Identities = 141/386 (36%), Positives = 203/386 (52%), Gaps = 3/386 (0%) Query: 45 TSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS 104 D + LT +E IR R ++ + P + F I ++G +GV G + Sbjct: 6 WQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPT 65 Query: 105 IKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLA 164 IKGYGC G+S A + E+ RVD+ + + V SSL M I GSE Q++KYLP LA Sbjct: 66 IKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLA 125 Query: 165 QLNTVACWALTEPDNGSDASGLGTTATKV--EGGWKINGQKRWIGNSTFADLLIIFARNT 222 + + C+ LTEP++GSD S + T A + +NG K WI NS ADL +++AR Sbjct: 126 KGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWAR-C 184 Query: 223 TTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSK 282 I GF+++K GL A +I K LR G I++ V VP+E+ LPG +S Sbjct: 185 EDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG 244 Query: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFL 342 L +R +AW +G S +Y +R QFG PLA QL Q+KL ML + Sbjct: 245 CLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLH 304 Query: 343 MGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLE 402 +L +L + + P SL K KA + A R++LGGNGI ++ V + +LE Sbjct: 305 ACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLE 364 Query: 403 PIYTYEGTYDINTLVTGREVTGIASF 428 + TYEGT+DI+ L+ GR +TGI +F Sbjct: 365 AVNTYEGTHDIHALILGRAITGIQAF 390 >1IVH-A nrPDB Length = 394 Score = 434 bits (1116), Expect = e-122, Method: Composition-based stats. Identities = 104/378 (27%), Positives = 175/378 (46%), Gaps = 9/378 (2%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFP--FHITPKLGAMGVAGGSIK-GYGC 110 L+ E++ +R+ + + +++ +AP E EF +LG +GV G + YG Sbjct: 12 GLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGG 71 Query: 111 PGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVA 170 GL + + EI+R + HS+L + + G+EAQKEKYLP L + Sbjct: 72 SGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIG 131 Query: 171 CWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT-----TTN 225 A++EP+ GSD + A K + +NG K WI N AD+LI++A+ + Sbjct: 132 ALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASR 191 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVL 284 I FIV+K PG +K +K+G+R +++ ++ +P + L N L Sbjct: 192 GITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGL 251 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 + R+++A P+G+ + D YL R+ FG + FQL Q K+ M + A Sbjct: 252 DLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYV 311 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 + + K + G T + + + A + A G + GGNG + DF + + D + Sbjct: 312 YNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLY 371 Query: 405 YTYEGTYDINTLVTGREV 422 GT ++ LV GR Sbjct: 372 EIGAGTSEVRRLVIGRAF 389 >2EBA-A nrPDB Length = 385 Score = 430 bits (1106), Expect = e-121, Method: Composition-based stats. Identities = 148/384 (38%), Positives = 218/384 (56%), Gaps = 3/384 (0%) Query: 47 DYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS-I 105 D+Y DLLTPEE+ ++K R +EKE P + ++WE+ FP H+ P+ +G G + Sbjct: 3 DFYALEDLLTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLP 62 Query: 106 KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQ 165 YG G+S A + E+ RVD+ +F+ V SSL M I GSE QK ++LP LA+ Sbjct: 63 PEYGGAGVSSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLAR 122 Query: 166 LNTVACWALTEPDNGSDASG-LGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT 224 V C+ LTEPD GSD G + T A + W +NG K WI N A L +I+A++ Sbjct: 123 GEMVGCFGLTEPDGGSDPYGNMKTRARREGDTWVLNGTKMWITNGNLAHLAVIWAKDEGG 182 Query: 225 NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVL 284 + GF+V D PG +A ++ K+ LR +++L+ V VP+ RLP + L Sbjct: 183 E-VLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRLPKALGLKAPLSCL 241 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 +R +AW +G +Y+ + K R FG PLA QL Q KL +ML L+ Sbjct: 242 TQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGLLLA 301 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 WRL +L + G++TP Q SL K KA + A + R++LGG+GI ++ + +LE + Sbjct: 302 WRLARLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLETV 361 Query: 405 YTYEGTYDINTLVTGREVTGIASF 428 YTYEGT+D++TLV GRE+TG+ +F Sbjct: 362 YTYEGTHDVHTLVLGREITGLNAF 385 >3SWO-A nrPDB Length = 399 Score = 427 bits (1098), Expect = e-120, Method: Composition-based stats. Identities = 124/401 (30%), Positives = 205/401 (51%), Gaps = 4/401 (0%) Query: 29 SVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFP 88 S+ + ST+ P + + + LL +E+ I VR+ ++ + P + ++E A P Sbjct: 2 SMTLTAPSKKSTYAPL--ELFDTDRLLDQDERDIAATVRQFVDTRLKPNVEGWFESATLP 59 Query: 89 FHITPKLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIA 148 + + G +GV G ++GYGC G + + +A E+ D+ +F+ V SL M +I Sbjct: 60 SELAKEFGNLGVLGMHLQGYGCAGTNAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIY 119 Query: 149 LCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGN 208 GSE QK ++LP LA + + C+ LTEPD GS+ +G+ T A + W +NG K WI N Sbjct: 120 RYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRDGSDWILNGTKMWITN 179 Query: 209 STFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDE 268 AD+ ++A+ I GF+V D PG A +I K+ LR +++L NV +P Sbjct: 180 GNLADVATVWAQTDD--GIRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPAS 237 Query: 269 DRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQ 328 +LP L +R + + +G + + Y + R+ F PL+ +QL Q+ Sbjct: 238 AQLPLAEGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQE 297 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGI 388 KL M + L+ L ++ + + P Q SLGK +A A R LLGG+GI Sbjct: 298 KLANMTVELGKGMLLAIHLGRIKDAEGVRPEQISLGKLNNVREAIAIARECRTLLGGSGI 357 Query: 389 LADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASFK 429 ++ + +LE + TYEGT +++ L G+ +TG A+F+ Sbjct: 358 TLEYSPLRHANNLESVLTYEGTSEMHLLSIGKALTGKAAFR 398 >4KTO-A nrPDB Length = 410 Score = 423 bits (1088), Expect = e-119, Method: Composition-based stats. Identities = 113/378 (29%), Positives = 177/378 (46%), Gaps = 5/378 (1%) Query: 50 HFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGY 108 N L E A+R VR + +AP+ + FP + ++G +G+ G + + + Sbjct: 28 GLNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAH 87 Query: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNT 168 G GL A+ +A EI+R AS HS+L + I G AQK +YLP L Sbjct: 88 GGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEH 147 Query: 169 VACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTT---TN 225 V A++EP GSD + A K + +NG K WI N AD+L+++A+ Sbjct: 148 VGALAMSEPGAGSDVVSMKLKADKRGDRYVLNGSKMWITNGPDADVLVVYAKTDPAAGPR 207 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVL 284 I F+V+K PG A + +K+G+R +++ + VP+E+ L GV + L Sbjct: 208 GITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLMSGL 267 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 RV+++ P+GI D+ YL ERKQFG P+ FQL Q KL M + A Sbjct: 268 DYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAARAYV 327 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 + + + G+ A+ + + KA A + LGGNG D+ + D + Sbjct: 328 YAVAAACDRGETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAKLY 387 Query: 405 YTYEGTYDINTLVTGREV 422 GT +I ++ GRE+ Sbjct: 388 EIGAGTSEIRRMLIGREL 405 >3PFD-A nrPDB Length = 393 Score = 422 bits (1086), Expect = e-118, Method: Composition-based stats. Identities = 120/397 (30%), Positives = 177/397 (44%), Gaps = 12/397 (3%) Query: 33 PQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHIT 92 P + A + P + L E A+R+ +R EKE+AP E EKA FP Sbjct: 2 PGSMAAWSGNPSFELF-----QLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEAL 56 Query: 93 PKLGAMGVAGGSI-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCG 151 L + G + + + YG G A I E+ARVD S S V+ LG + + L G Sbjct: 57 AALNSSGFSAIHVPEEYGGQGADSVATCIVIEEVARVDCSASLIPAVNK-LGTMGLILRG 115 Query: 152 SEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTF 211 SE K++ LP++A +A +AL+E + GSDA+ + T A W +NG K WI N Sbjct: 116 SEELKKQVLPAVASGEAMASYALSEREAGSDAASMRTRAVADGDDWILNGSKCWITNGGK 175 Query: 212 ADLLIIFARNTTT---NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDE 268 + + A N I+ F+V KD G K+G++ ++ +N +P + Sbjct: 176 STWYTVMAVTDPDKGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGD 235 Query: 269 DRLPGVN-SFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQ 327 + F+ L +R + Q +GI+ G D Y KERKQFG P++ Q Q Sbjct: 236 RIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQ 295 Query: 328 QKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLG-KAWISSKARETASLGRELLGGN 386 L M ++A LM + E G+ G S K + S A E + +L GG Sbjct: 296 FMLADMAMKIEAARLMVYSAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGY 355 Query: 387 GILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVT 423 G DF V + D + YEGT I +V R + Sbjct: 356 GYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALL 392 >2JIF-A nrPDB Length = 404 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 112/375 (29%), Positives = 181/375 (48%), Gaps = 6/375 (1%) Query: 53 DLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYGCP 111 T EE I+ V++ ++++AP+++ E ++ + L G+ G + YG Sbjct: 27 QTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGT 86 Query: 112 GLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVAC 171 G S + + E+A+VDAS + F + ++L I G+E QK YLP L V Sbjct: 87 GASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGS 145 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT---NQIN 228 + L+E GSD+ L T A K + +NG K WI ++ A L ++ A T I Sbjct: 146 FCLSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYKGIT 205 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVS 287 F+V +D PGL K NK+GLR + +NV VP+ + L + ++ L Sbjct: 206 SFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNEG 265 Query: 288 RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRL 347 R+ +A Q +G++ G +D Y+KER QFG L FQ Q ++ + ++A L+ + Sbjct: 266 RIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYNA 325 Query: 348 CKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTY 407 +L E G+ +AS+ K + S A +T S E +GG G D+ V K F D + Y Sbjct: 326 ARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTIY 385 Query: 408 EGTYDINTLVTGREV 422 EG +I + + Sbjct: 386 EGASNIQLNTIAKHI 400 >4W9U-A nrPDB Length = 395 Score = 416 bits (1069), Expect = e-116, Method: Composition-based stats. Identities = 127/396 (32%), Positives = 208/396 (52%), Gaps = 4/396 (1%) Query: 35 ATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPK 94 + + F D + + LT +E+ IR + + P + + + + + Sbjct: 1 SMSRAAFA--WEDPFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHL 58 Query: 95 LGAMGVAGGSIKG-YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSE 153 +G G+ G ++ YG S A + E+ R+D+ + + V SSL M I GS+ Sbjct: 59 MGQAGLLGVTLPEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSD 118 Query: 154 AQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFAD 213 Q++KYLP L + C+ LTEPD GSD +G+ T A K++GG++++G K WI NS AD Sbjct: 119 EQRKKYLPGLVSGELIGCFGLTEPDAGSDPAGMKTRAEKIDGGYRLSGSKMWISNSPIAD 178 Query: 214 LLIIFARNTT-TNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP 272 + +++A++ N I GFI++K GL A KI K+ LR G+I++ V V ++ LP Sbjct: 179 VFVVWAKSAAHDNAIRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAILP 238 Query: 273 GVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQ 332 V+ + L +R ++W +G + + +Y +RKQF PLA QL Q+KL Sbjct: 239 NVSGLKGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLAD 298 Query: 333 MLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADF 392 M + R+ +L++ G+M P S+ K KA + A R++ GGNGI ++ Sbjct: 299 MQTEIALGIQASLRVGRLFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEY 358 Query: 393 LVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASF 428 V + +LE + TYEGT+D++ L+ GR TGI +F Sbjct: 359 HVMRHAQNLETVNTYEGTHDVHALILGRAQTGIQAF 394 >2DVL-A nrPDB Length = 372 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 119/370 (32%), Positives = 183/370 (49%), Gaps = 4/370 (1%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS-IKGYGCPGL 113 LT E++ + VR + + P+ EY KAE+P+ L +G+ G + + +G GL Sbjct: 3 LTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 A+A E+A D S + + V S L + GSEAQK +YL LA+ + + Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVK 233 LTEP GSDA L A +V+GG+ +NG K WI ++ A L ++ AR I+ F+V+ Sbjct: 123 LTEPQAGSDAKSLRAEARRVKGGFVLNGVKSWITSAGHAHLYVVMART--EKGISAFLVE 180 Query: 234 KDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSRVMVA 292 K PGL + K+GL ++ L+ VFVP+E+ L L RV VA Sbjct: 181 KGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGLDSGRVGVA 240 Query: 293 WQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYE 352 Q +GI+ G +++ Y +ER+QFG L Q K+ M + A + + + Sbjct: 241 AQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLEAARKKD 300 Query: 353 TGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYD 412 G+ +AS K + S+ A E ++LGG G D+ V + + D + YEGT + Sbjct: 301 RGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEIYEGTSE 360 Query: 413 INTLVTGREV 422 I LV RE+ Sbjct: 361 IQRLVIAREL 370 >2PG0-A nrPDB Length = 385 Score = 408 bits (1050), Expect = e-114, Method: Composition-based stats. Identities = 93/375 (24%), Positives = 170/375 (45%), Gaps = 8/375 (2%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGL 113 L E R R+ +EKE P ++ ++ P K+G G + YG Sbjct: 10 LREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNA 69 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 + + E+ +V +S I +H+ + IA G+E QK+K+LP + A Sbjct: 70 DFAYSVVINEELEKVGSSLVG-IGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIA 128 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT-----TTNQIN 228 +TEP GSD + + TTA K + +NGQK +I N ADL+++ + I+ Sbjct: 129 MTEPGAGSDLANISTTAVKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPPHRGIS 188 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVS 287 +V++D PG + K+GL ++ Q+ VP + L F + L Sbjct: 189 LLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEEGKGFYYLMEKLQQE 248 Query: 288 RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRL 347 R++VA + ++ + +Y+K+R FG ++ FQ Q +L +M + R+ Sbjct: 249 RLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFVDRV 308 Query: 348 CKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTY 407 + + G+ + S+ K WI+ A+ A+ +L GG G + ++ +A+ + D+ Y Sbjct: 309 IEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAIY 368 Query: 408 EGTYDINTLVTGREV 422 GT ++ + R++ Sbjct: 369 AGTNEMMKTIIARQL 383 >1RX0-A nrPDB Length = 393 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 96/375 (25%), Positives = 166/375 (44%), Gaps = 6/375 (1%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPG 112 L E++ +K + +E+AP M E+ +K FP + K +G G I+ G G Sbjct: 18 GLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSG 77 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACW 172 LS ++ +A S + +I +H+ + I G+E Q+ K+ P L + A + Sbjct: 78 LSRLDTSVIFEALATGCTSTTAYISIHNMCAWM-IDSFGNEEQRHKFCPPLCTMEKFASY 136 Query: 173 ALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN--QINGF 230 LTEP +GSDA+ L T+A K + +NG K +I + +D+ ++ R I+ Sbjct: 137 CLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI 196 Query: 231 IVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP-GVNSFQDTSKVLAVSRV 289 +V+K PGL K K+G ++ ++ VP +R+ F + L R+ Sbjct: 197 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 256 Query: 290 MVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC- 348 +A +G + + +L RKQFG PLA+ Q Q L M + A LM Sbjct: 257 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 316 Query: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 L E + S+ K + + + + ++ GG G L D+ V + D E Sbjct: 317 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 376 Query: 409 GTYDINTLVTGREVT 423 G+ ++ ++ R + Sbjct: 377 GSNEVMRILISRSLL 391 >4IV6-A nrPDB Length = 388 Score = 403 bits (1036), Expect = e-113, Method: Composition-based stats. Identities = 102/380 (26%), Positives = 173/380 (45%), Gaps = 10/380 (2%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGL 113 LT EE+ I K V + +EK+V P++ E +P + + +G+ G +I YG + Sbjct: 7 LTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAV 66 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 S+ E+AR S + + H+ + L + L G+E QK+KYLP +A A A Sbjct: 67 SMPCYVQVAEELARGWMSLAGAMGGHTVVSKL-LLLFGTEEQKQKYLPRMATGELRATMA 125 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT-----NQIN 228 LTEP GSD + T A + + ING K WI N+ +DL+ + + ++ Sbjct: 126 LTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKGVS 185 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP--GVNSFQDTSKVLAV 286 +V+K PG ++ K+G + V++ ++ + VP L F K L V Sbjct: 186 ILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGLEV 244 Query: 287 SRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWR 346 R+ VA + G++ ++ RY +ER+ FG P+ Q L M + A + Sbjct: 245 GRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLLLS 304 Query: 347 LCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYT 406 + ++ GQ +A + K + S A + A + GG G ++ V + F D + Sbjct: 305 AAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPLMIV 364 Query: 407 YEGTYDINTLVTGREVTGIA 426 EGT +I V +++ Sbjct: 365 GEGTNEIQRNVIAKQLVARG 384 >3NF4-A nrPDB Length = 387 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 103/390 (26%), Positives = 164/390 (42%), Gaps = 8/390 (2%) Query: 37 PASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLG 96 P S P D L + E + + RE +K + PI+ + + +P + +LG Sbjct: 2 PGSMIHPMAVDRL----LPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLG 57 Query: 97 AMGVAG-GSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQ 155 A G+ + +G G EIA AS + + VH SL + + G+E Q Sbjct: 58 AAGLLSLPQPEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVH-SLSSHPLLVFGTEEQ 116 Query: 156 KEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLL 215 K+++LP + + ++L+EP GSDA+ L AT +GG+ ING K WI + AD Sbjct: 117 KKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFY 176 Query: 216 IIFARNT-TTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV 274 +FAR + ++ F+V D PGL K K+GL V N + + R+ Sbjct: 177 TLFARTGEGSRGVSCFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEE 236 Query: 275 N-SFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQM 333 Q L R+ +A G++ D Y ER FG + Q L M Sbjct: 237 GQGLQIAFSALDSGRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADM 296 Query: 334 LGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFL 393 V + + G+ QAS+ K + A + + ++ GG G D+ Sbjct: 297 AAAVATARATYLDAARRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYR 356 Query: 394 VAKAFCDLEPIYTYEGTYDINTLVTGREVT 423 V + + + + +EGT I LV R +T Sbjct: 357 VERYMREAKIMQIFEGTNQIQRLVIARGLT 386 >2CX9-A nrPDB Length = 387 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 120/376 (31%), Positives = 181/376 (48%), Gaps = 9/376 (2%) Query: 57 PEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGLSI 115 EE+ + RE ++ EVAP E FP+ + KL GV G + YG GLS Sbjct: 9 AEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAYGGAGLST 68 Query: 116 TANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALT 175 A IA D + + + H+SL I L GSEAQKE +LP LA + W LT Sbjct: 69 RLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLT 128 Query: 176 EPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT-------NQIN 228 EP +GSDA+ L T A KVEGGW++NG K++I + A + ++ AR I+ Sbjct: 129 EPGSGSDAAALKTKAEKVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSPERKHQGIS 188 Query: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP-GVNSFQDTSKVLAVS 287 F + GLK + K+GL ++L+++FVP+E L F D +VL Sbjct: 189 AFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGFYDVLRVLDGG 248 Query: 288 RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRL 347 R+ +A +G+ D Y K R+ FG P+A F+ KL + ++A L+ + Sbjct: 249 RIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARLLYLKA 308 Query: 348 CKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTY 407 +L + G+ +A+ K + S A + ++LGG G + D+ V + + D Sbjct: 309 AELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWRDARLTRIG 368 Query: 408 EGTYDINTLVTGREVT 423 EGT +I LV R + Sbjct: 369 EGTSEILKLVIARRLL 384 >3MPI-A nrPDB Length = 397 Score = 383 bits (983), Expect = e-106, Method: Composition-based stats. Identities = 105/385 (27%), Positives = 183/385 (47%), Gaps = 11/385 (2%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHI-TPKLGAMGVAGGSI-KGY 108 + L+ E Q ++K+VR + K++ P ++ + FP+ +G +G G I + Y Sbjct: 1 MDFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEY 60 Query: 109 GCPGLSI--TANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQL 166 G G+ A I T EIAR ++ + + TI GSEA K+KY+P L+ Sbjct: 61 GGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSA 120 Query: 167 NTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT---T 223 + + +TEPD GSD + +TA W +NG K WI N+ AD+LI +A Sbjct: 121 EFLGGFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTDKAAG 180 Query: 224 TNQINGFIV-KKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTS 281 + ++ F++ ++ PG+K + + K+G G++ L NV VP E+ L + Sbjct: 181 SRGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGARIVF 239 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 L +R+ A +G++ D +Y ER+QFG P+ FQ+NQ + QM V+A Sbjct: 240 GSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVEAAR 299 Query: 342 LMGWRLCKLYETGQ-MTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCD 400 L+ ++ + G+ ++ K + A+ +LG G ++ VA+ + D Sbjct: 300 LLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARFYRD 359 Query: 401 LEPIYTYEGTYDINTLVTGREVTGI 425 Y EG+ +I ++ + G+ Sbjct: 360 APTYYMVEGSANICKMIIALDQLGV 384 >3OWA-A nrPDB Length = 597 Score = 380 bits (976), Expect = e-106, Method: Composition-based stats. Identities = 114/402 (28%), Positives = 190/402 (47%), Gaps = 33/402 (8%) Query: 47 DYYHFNDLLTPE-----EQAIRKKVRECMEKEVAPIMTEYWEKAEFPFH--ITPKLGAMG 99 D + + TPE + I K + + EV P + EY E+ EF + + G +G Sbjct: 20 DEITIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPEL-EYLEQHEFDRSVRLLKEAGELG 78 Query: 100 VAGGSI-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEK 158 + G + + YG GL ++A+ + +R + H +G L I L G+E QK+K Sbjct: 79 LLGADVPEEYGGIGLDKVSSALIAEKFSRA-GGFAITHGAHVGIGSLPIVLFGNEEQKKK 137 Query: 159 YLPSLAQLNTVACWALTEPDNGSDASGLGTTATK--VEGGWKINGQKRWIGNSTFADLLI 216 YLP LA +A +ALTEP +GSDA G TTA + +NG+K+WI NS FAD+ I Sbjct: 138 YLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFI 197 Query: 217 IFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS 276 ++A+ + + FIV+KD G+ + K+G++ ++L++ VP E+ L + Sbjct: 198 VYAKIDGEH-FSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGK 256 Query: 277 FQ-DTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLG 335 +L + R + +G + ++ +Y +R+QF P+A F L Q+KL M Sbjct: 257 GHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAA 316 Query: 336 NVQAMFLMGWRLCKLYET------------GQMTPG-------QASLGKAWISSKARETA 376 A +R L+E+ G+ + SL K + S T Sbjct: 317 KTYAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTV 376 Query: 377 SLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVT 418 G ++ GG G +A++ + + + D +EGT +IN L+ Sbjct: 377 DEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIV 418 >2Z1Q-A nrPDB Length = 577 Score = 379 bits (974), Expect = e-105, Method: Composition-based stats. Identities = 110/392 (28%), Positives = 178/392 (45%), Gaps = 28/392 (7%) Query: 52 NDLLTPEE-----QAIRKKVRECMEKEVAPIMTEYWEKAEFP--FHITPKLGAMGVAGGS 104 + TPE+ + I + R +E+EV P++ E E E + K G +G+ Sbjct: 20 ERVYTPEDFDESVKEIARTTRTFVEREVLPLL-ERMEHGELELNVPLMRKAGELGLLAID 78 Query: 105 I-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSL 163 + + YG L + + E++ S H+S+G L + G+E QK KYLP L Sbjct: 79 VPEEYGGLDLPKVISTVVAEELS-GSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKL 137 Query: 164 AQLNTVACWALTEPDNGSDASGLGTTATKVEGG--WKINGQKRWIGNSTFADLLIIFARN 221 A +A + LTEP +GSDA T AT E G + +NG K+WI N+ FA L +FA+ Sbjct: 138 ASGEWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAKV 197 Query: 222 TTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPG-VNSFQDT 280 + F+V++D PGL K+G++ ++L++V VP E+ L + Sbjct: 198 DGEH-FTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGKGHKIA 256 Query: 281 SKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAM 340 VL V R + +G + ++ +Y +R QFG P+ F L QQKL +M + A Sbjct: 257 FNVLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAA 316 Query: 341 FLMGWRLCKLYETG--------------QMTPGQASLGKAWISSKARETASLGRELLGGN 386 +R L + + +AS+ K S G ++ GG Sbjct: 317 ESAVYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGY 376 Query: 387 GILADFLVAKAFCDLEPIYTYEGTYDINTLVT 418 G ++ + +A+ D +EGT +IN L+ Sbjct: 377 GYSQEYPIERAYRDARINRIFEGTNEINRLLI 408 >3B96-A nrPDB Length = 587 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 106/408 (25%), Positives = 170/408 (41%), Gaps = 27/408 (6%) Query: 45 TSDYYHFNDLLTPEE----QAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGV 100 T + + +L E+ + + + V E+ P + E E L +G Sbjct: 16 TDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVE--ETTWQGLKELGA 73 Query: 101 AGGSIK-GYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKY 159 G + G GL T A + D + H S+G I L G++AQKEKY Sbjct: 74 FGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKY 133 Query: 160 LPSLAQLNTVACWALTEPDNGSDASGLGTTATKV--EGGWKINGQKRWIGNSTFADLLII 217 LP LA TVA + LTEP +GSDA+ + T+A + +NG K WI N AD+ + Sbjct: 134 LPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTV 193 Query: 218 FARN--------TTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDED 269 FA+ +I F+V++ G+ K+G++ ++ V VP E+ Sbjct: 194 FAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSEN 253 Query: 270 RLPGVN-SFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQ 328 L V F+ +L R +A G GI + R QFG + F L Q+ Sbjct: 254 VLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQE 313 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYETGQM-TPGQASLGKAWISSKARETASLGRELLGGNG 387 KL +M+ M + + + G +A++ K + S A + +++GG G Sbjct: 314 KLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMG 373 Query: 388 ILADFLVAKAFCDLEPIYTYEGTYDINTLVTG--------REVTGIAS 427 + + V + DL +EGT DI L +E++G+ S Sbjct: 374 FMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 421 >3R7K-A nrPDB Length = 403 Score = 361 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 82/372 (22%), Positives = 157/372 (42%), Gaps = 5/372 (1%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAG-GSIKGYGCPGLS 114 TPE +A+ + R +E+E+AP + E+ E P + +G+ G G + G G + Sbjct: 30 TPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVGGSGGN 89 Query: 115 ITANAIATAEIARVDASCST-FILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 +A+ T I S L + + IA GS+A E+Y+ + Sbjct: 90 AIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLAGKMIGSLG 149 Query: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN--QINGFI 231 +TEP GSD + L T A + + +NG K +I + AD + R ++ + Sbjct: 150 VTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTGGPGYGGVSLLV 209 Query: 232 VKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSRVM 290 + K++PG + ++ +K+G R ++ +V VP ++ + N F + R+ Sbjct: 210 IDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQQFQAERLG 269 Query: 291 VAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKL 350 +A Q + D+ + +ER+ FG PL Q+ + KL +M V + + Sbjct: 270 IAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACTYTRAVMQR 329 Query: 351 YETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGT 410 + G+ + S+ K + ++ GG G + + + + + D + GT Sbjct: 330 WLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRILGIGGGT 389 Query: 411 YDINTLVTGREV 422 +I V + + Sbjct: 390 NEIMNEVIAKRI 401 >6ES9-A nrPDB Length = 551 Score = 359 bits (921), Expect = 2e-99, Method: Composition-based stats. Identities = 93/387 (24%), Positives = 167/387 (43%), Gaps = 19/387 (4%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEF-PFHITPKLGAMGVAGGSI-KGYGCP 111 L + + IR + R E+ V P E+ K + P I +L +GV G +I + +G Sbjct: 166 GLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGL 225 Query: 112 GLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVAC 171 GLS + + T E++R + + S + I G+EAQK K+LP LA ++ Sbjct: 226 GLSKASMVVVTEELSRGYIGVGS-LGTRSEIAAELILCGGTEAQKAKWLPGLASGEILST 284 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT----TTNQI 227 TEP+ GSD L T A + W + G K WI ++ ++ + AR + Sbjct: 285 AVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGL 344 Query: 228 NGFIVKKD---------APGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV--NS 276 + F+ +K+ PG+ +I +G R ++ ++ + E+ L G Sbjct: 345 SMFLAEKEPGTDDDPFPTPGMTGGEIE-VLGYRGMKEYELGFDGFRIKGENLLGGEPGRG 403 Query: 277 FQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGN 336 F+ + +R+ A + +G++ ++ RY +RKQFG L F KL M Sbjct: 404 FKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVE 463 Query: 337 VQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAK 396 + + + + G+ +A + K + A A ++ GGNG ++ +++ Sbjct: 464 IMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISR 523 Query: 397 AFCDLEPIYTYEGTYDINTLVTGREVT 423 CD + +EG +I V R + Sbjct: 524 VLCDARILNIFEGAAEIQAQVIARRLL 550 >4IRN-A nrPDB Length = 416 Score = 355 bits (912), Expect = 2e-98, Method: Composition-based stats. Identities = 101/379 (26%), Positives = 164/379 (43%), Gaps = 7/379 (1%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YG 109 F+ ++ RKKV + ++ + + + ++ F K GV G I YG Sbjct: 36 FDFAWNSQQIQFRKKVIQFAQQSLISDLIKNDKEEIFNRDAWQKCSEFGVHGWPIPARYG 95 Query: 110 CPGLSITANAIATAEIARV--DASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 L I A A + D + H + + G+E QKEKYLP L + Sbjct: 96 GQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTFGTEEQKEKYLPLLCRGG 155 Query: 168 TVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTT---T 224 +A A TEP GSD L TTA K + +NG K ++ N T ADL IIFA Sbjct: 156 WIASHAATEPQAGSDIYSLKTTAQKDGDKYILNGYKHYVTNGTIADLFIIFATIDPSLGK 215 Query: 225 NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKV 283 + F+++KD PGL +K +K+G+R + ++ L+N V +RL + Sbjct: 216 EGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEVSAANRLGEEGTGLAIFNHS 275 Query: 284 LAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLM 343 + R + +G + + RY + KQFG + FQL KLV+M ++ Sbjct: 276 MEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKFQLVANKLVEMKLRLENAKAY 335 Query: 344 GWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEP 403 +++ + E QM +AS+ +IS ++ E+ G G L + + + D Sbjct: 336 LYKVAWMKENKQMALLEASMANLYISEAWVQSCLEAIEIHGAYGYLTNTELERELRDAIA 395 Query: 404 IYTYEGTYDINTLVTGREV 422 Y GT +I +V + + Sbjct: 396 SKFYSGTSEIQRVVIAKFL 414 >5ZW7-A nrPDB Length = 402 Score = 345 bits (885), Expect = 2e-95, Method: Composition-based stats. Identities = 87/382 (22%), Positives = 160/382 (41%), Gaps = 13/382 (3%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KGYG 109 + L+ + I + + + + K A G A G + +G Sbjct: 1 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFG 60 Query: 110 CPGLSITANAIATAEIARV--DASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 L A+ + + D S + H ++ + GS K+KYL SL Sbjct: 61 GSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGK 120 Query: 168 TVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ- 226 +A A TEPD GSD + TA EGG+ +NG+K +I N+ AD+ II+A+ + Sbjct: 121 LIAANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPDHGF 180 Query: 227 --INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLP----GVNSFQDT 280 ++ F+++K PGL ++ K L +I+ ++F+P R+ G F D+ Sbjct: 181 LGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDS 240 Query: 281 SKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAM 340 + ++ +G + + Y K R+QFG + FQ +++ M ++ Sbjct: 241 M---IWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQC 297 Query: 341 FLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCD 400 LM +R C ++ GQ ++ K IS A ++ + GG + + + + + Sbjct: 298 RLMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLN 357 Query: 401 LEPIYTYEGTYDINTLVTGREV 422 + P + GT DI + R++ Sbjct: 358 MIPSRIFSGTNDIQKEIIARKL 379 >3P4T-A nrPDB Length = 403 Score = 341 bits (874), Expect = 4e-94, Method: Composition-based stats. Identities = 85/399 (21%), Positives = 147/399 (36%), Gaps = 6/399 (1%) Query: 30 VAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPF 89 +A T T + T E +A+RK VR E+EV P E+ E P Sbjct: 1 MAHHHHHHMGTLEAQTQGPGSMSIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPR 60 Query: 90 HITPKLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFIL--VHSSLGMLTI 147 + K +G+ G A+ + E S + + + Sbjct: 61 ELHRKAAELGLLGAGFPEDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHM 120 Query: 148 ALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIG 207 G + + Y+ + + A+TEP GSD L T A + ING K +I Sbjct: 121 IASGDQRLIDTYVRPTLRGEKIGALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYIT 180 Query: 208 NSTFADLLIIFARNTTT--NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFV 265 + AD ++ AR ++ +V K PG + T+ +K+G R ++ +V V Sbjct: 181 SGVRADYVVTAARTGGPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRV 240 Query: 266 PDEDRLPGVN-SFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQ 324 P + + N F + RV +A Q + D+ + + R FG PL + Q Sbjct: 241 PVANLVGSENTGFAQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQ 300 Query: 325 LNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMT-PGQASLGKAWISSKARETASLGRELL 383 Q L M + + + + G+ + K A+ +L Sbjct: 301 AVQNTLAGMARRIDVARVYTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLF 360 Query: 384 GGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 GG G +A+ V + + D+ + GT +I T + + + Sbjct: 361 GGMGYMAESEVERQYRDMRILGIGGGTTEILTSLAAKTL 399 >5IDU-A nrPDB Length = 410 Score = 336 bits (862), Expect = 1e-92, Method: Composition-based stats. Identities = 95/378 (25%), Positives = 156/378 (41%), Gaps = 13/378 (3%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVA--GGSIKGYGCP 111 + + + + +A ++ + + LG G G YG Sbjct: 25 FFEARHRELAAGIEAWATQHLA--CVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGH 82 Query: 112 G--LSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 G + A + +A D + F L LG I L G+ QK +YLP +++ + Sbjct: 83 GDTIDTRAVCLLRETLANHD-GLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAI 141 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT---TTNQ 226 A +AL+EPD GSD + + A + I+G K WI N AD ++FAR Sbjct: 142 AAFALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARG 201 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLA 285 I+ FIV D PGL+ + + I + + VP L F+ + L Sbjct: 202 ISAFIVDADTPGLQIAERIDVIAPH--PLARLHFDSARVPRSQMLGAPGEGFKIAMRTLD 259 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 V R VA +G + RK FG L FQL Q KL QM + + L+ + Sbjct: 260 VFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVY 319 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 R L + G+ +A++ K S A++ +L GG G+ + V + + ++ + Sbjct: 320 RAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALR 379 Query: 406 TYEGTYDINTLVTGREVT 423 YEG ++ L+ GR++ Sbjct: 380 IYEGATEVQQLIVGRDLL 397 >5JSC-A nrPDB Length = 410 Score = 315 bits (807), Expect = 3e-86, Method: Composition-based stats. Identities = 92/378 (24%), Positives = 158/378 (41%), Gaps = 13/378 (3%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVA----GGSIKGYG 109 P + + + +A ++ + + +LGA G GG G Sbjct: 25 FFEPRHRELAAGIEAWCRANLA--HEDHEDVDATCRRLVRELGAAGWLKYGVGGVAYGGH 82 Query: 110 CPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 + A + +A+ + + F L LG I+L G+ QK +YLP +A + Sbjct: 83 GDTIDTRAVCLLRETLAKH-SGLADFALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAI 141 Query: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT---TTNQ 226 A +AL+EP+ GSD + + +A + + ++G K WI N AD ++FAR Sbjct: 142 AAFALSEPEAGSDVAAMTLSAREDGDAYVLDGDKTWISNGGIADFYVVFARTGEAPGARG 201 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLA 285 I+ F+V D PGL+ + + I + VP L F+ + L Sbjct: 202 ISAFVVDADTPGLEIAERIDVIAPH--PLARLHFAGARVPRSQMLGAPGEGFKLAMRTLD 259 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 + R VA +G + RK FG L FQL Q KL QM + + L+ + Sbjct: 260 IFRTSVAAASLGFARHAMAEGVARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLVY 319 Query: 346 RLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIY 405 R L + G+ +A++ K S A++ +L GG G+ + V + ++ + Sbjct: 320 RAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRALR 379 Query: 406 TYEGTYDINTLVTGREVT 423 YEG ++ L+ GR++ Sbjct: 380 IYEGATEVQQLIVGRDLL 397 >5AHS-A nrPDB Length = 401 Score = 314 bits (804), Expect = 7e-86, Method: Composition-based stats. Identities = 95/394 (24%), Positives = 154/394 (39%), Gaps = 21/394 (5%) Query: 54 LLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPG 112 LTPE++ ++ + RE + A + ++P+ +L G G + G G Sbjct: 3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRG 62 Query: 113 LSITANAIATAEIARVDASCSTFILVHSSLG-MLTIALCGSEAQKEKYLPSLAQLNTVAC 171 LS I E+A+ A+ I V S+LG + I GSE Q K L Sbjct: 63 LSTLDTVIVIEEMAKACATMG-RITVDSNLGAIGAITKYGSEEQI-KLAADLVLAGDKPA 120 Query: 172 WALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR---NTTTNQIN 228 ++EP+ GS AS + T A K + +NG+K WI + L +IFAR + I Sbjct: 121 ICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIG 180 Query: 229 GFIVKKDA---PGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL----PGVNSFQDTS 281 FI D GLK + +G+R + + ++ + + F Sbjct: 181 AFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALM 240 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 RV +GI+ ++ YLK R+QFG PLA FQ Q + M ++A Sbjct: 241 SAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAAR 300 Query: 342 LMGWRLCKLYETGQMTPG--QASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFC 399 LM +G+ P +A+ K + + A + + + G +G + + Sbjct: 301 LMLRSAAV---SGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVR 357 Query: 400 DLEPIYTYEGTYDINTLVTGREVTGIASFKPATR 433 D GT I ++ + P TR Sbjct: 358 DARMFTIAGGTAQILRTQVASKILDMKL--PQTR 389 >6CY8-B nrPDB Length = 380 Score = 312 bits (799), Expect = 2e-85, Method: Composition-based stats. Identities = 78/381 (20%), Positives = 134/381 (35%), Gaps = 13/381 (3%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YG 109 N T E+ + + ++ AP+ E FP LG G G I Y Sbjct: 1 MNFEWTHEQAELFEHALRFGKELSAPLQ----EDNGFPRDNWNALGDFGYFGLPIPEKYA 56 Query: 110 --CPGLSITANAIATAEIARVDASCSTFIL--VHSSLGMLTIALCGSEAQKEKYLPSLAQ 165 G I + + H+ + I GSE K + LP LA Sbjct: 57 KDGSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLAT 116 Query: 166 LNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN 225 +A A++E GSD S L TTA K + +NG K ++ N + AD +++A + Sbjct: 117 GRKIAANAISEASAGSDISNLATTAQKEGDYYVLNGGKSYVTNGSIADYYVVYATTNKKH 176 Query: 226 Q---INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTS 281 F+V ++ PG+ +K+GLR + N + + L + + Sbjct: 177 GYLGQTAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGARIFA 236 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 + R + +G + C Y R Q ++ FQ ++ M +++ Sbjct: 237 ASMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLESAR 296 Query: 342 LMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 LM + ++ K IS ++ + G G L + V + D Sbjct: 297 LMLYYAAWQKSQDVDNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVNNSIKDA 356 Query: 402 EPIYTYEGTYDINTLVTGREV 422 + GT DI + + Sbjct: 357 LGSVLFSGTSDIQRELICNRL 377 >4RM7-A nrPDB Length = 391 Score = 305 bits (782), Expect = 2e-83, Method: Composition-based stats. Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 11/375 (2%) Query: 53 DLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAE-FPFHITPKLGAMGVAG-GSIKGYGC 110 D L+ +EQ + VRE EK P W K + P + + G G I Sbjct: 6 DGLSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHRRNH 65 Query: 111 PGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVA 170 + A + E++R+ +C F + L + + S AQ + ++ Sbjct: 66 RTYDLFAQVLVIEELSRISGACLPF--QNDLLQLQILEAFASSAQTSPFRTEYQDTGRLS 123 Query: 171 -CWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTN---- 225 A++EP+ GSD + T T+ +NG K ++ N +A L++ A + T + Sbjct: 124 YALAISEPEAGSDTRSMRTHVTREGDTLVMNGTKMFVNNGEYAPALLVSAYDKTGDDGEP 183 Query: 226 QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVL 284 + + ++V + A G+ A KIG M+ + NV V + RL G F +L Sbjct: 184 EFSFWMVPRSAAGIYAYP-EQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQLYSLL 242 Query: 285 AVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMG 344 RV +G + + + + R+ FG +A Q Q KL +M + M + Sbjct: 243 EYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTNMRNLV 302 Query: 345 WRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPI 404 + + Y+ G+ +L K ++ A E AS ++LGG G + + V+ + D Sbjct: 303 YGAAREYDRGEHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQDCRGY 362 Query: 405 YTYEGTYDINTLVTG 419 +GT ++ ++ Sbjct: 363 QFADGTDEVMVVIAA 377 >2WBI-A nrPDB Length = 428 Score = 281 bits (720), Expect = 3e-76, Method: Composition-based stats. Identities = 80/413 (19%), Positives = 156/413 (37%), Gaps = 28/413 (6%) Query: 35 ATPASTFPPCTSDYYHFNDLL--TPEEQAIRKKVRECMEKEVAPI---MTEYWEKAEFPF 89 + TF L T + Q + KV+ M++ + P +TE++ + E Sbjct: 1 SMSKRTFSTVLPQIDTTGQLFVQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSV 60 Query: 90 H------ITPKLGAMGVAGGSIKGY--GCPGLSITANAIATAEIARVDASCSTFILVHSS 141 + KL M G + GLS A+ E + + F Sbjct: 61 DKWGKPLVIDKLKEMAKVEGLWNLFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPD 120 Query: 142 LG-MLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPD-NGSDASGLGTTATKVEGGWKI 199 G M + L GSE QK+++L L Q N +C+ +TEPD SDA+ + + + E + I Sbjct: 121 TGNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVI 180 Query: 200 NGQKRWIGNS--TFADLLIIFARNTTTN-----QINGFIVKKDAPGLKATKIPNKIGLRM 252 NG+K W + + I+ R T+ Q + +V + PG+K + + G Sbjct: 181 NGKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTD 240 Query: 253 VQNG---DILLQNVFVPDEDR-LPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHR 308 +G +I V VP + L F+ + L R+ + +G++ + Sbjct: 241 NFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCE 300 Query: 309 YLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYET--GQMTPGQASLGKA 366 +R F L A ++ + + ++ + L+ + +T + ++ K Sbjct: 301 RATQRIAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKV 360 Query: 367 WISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTG 419 + ++ GG G+ D+ +A + + +G +++ Sbjct: 361 AAPRAVSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIA 413 >4HR3-A nrPDB Length = 415 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 86/406 (21%), Positives = 153/406 (37%), Gaps = 34/406 (8%) Query: 48 YYHFNDLLTPEEQAIRKKVRECMEKEVAPI------------------MTEYWEKAEFPF 89 + + + VRE ++ EV P+ E W Sbjct: 2 PGSMDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELD 61 Query: 90 HITPKLGAMGV--AGGSIKGYGCPGLSITANAIATAEIARVDASCSTFIL-VHSSLGMLT 146 + K A G+ G GLS + A ++ R + + F S M Sbjct: 62 SLKAKARAAGLWNLFLPDPELGG-GLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEV 120 Query: 147 IALCGSEAQKEKYLPSLAQLNTVACWALTEPD-NGSDASGLGTTATKVEGGWKINGQKRW 205 + GS+ QKE +L L + + + + +TEPD SDA+ + TA ING+K W Sbjct: 121 LHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWW 180 Query: 206 IGNSTFADL-LIIFARNTTTNQI-----NGFIVKKDAPGLKATKIPNKIGLRMVQNGD-- 257 D +IIF T N + +V D PG+ ++ +G G Sbjct: 181 STGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGV 240 Query: 258 ILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQF 316 + NV +P + + G F+ L RV A + IG++ + R +R F Sbjct: 241 VSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAF 300 Query: 317 GAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLG--KAWISSKARE 374 G PL N++++ + L+ L +T + +++ K + A++ Sbjct: 301 GKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQ 360 Query: 375 TASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 + ++ GG G+ DF +A A+ + + +G +++ V R Sbjct: 361 VIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVAR 406 >4X28-A nrPDB Length = 400 Score = 252 bits (643), Expect = 3e-67, Method: Composition-based stats. Identities = 86/400 (21%), Positives = 144/400 (36%), Gaps = 38/400 (9%) Query: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPF-------HITPKLGAMGVAG-GSIK 106 TP+++ +R+++R + P E + + ++G G G K Sbjct: 5 YTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPK 64 Query: 107 GYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQL 166 YG G S I T E A + + F+ ++S TI G++ QK +LP +A Sbjct: 65 EYGGQGRSAMDQLIFTDE-AAIAGAPVPFLTINS--VAPTIMAYGTDEQKRFFLPRIAAG 121 Query: 167 NTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT-- 224 + +EP G+D + L TTA + + +NGQK W +AD + + R Sbjct: 122 DLHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESS 181 Query: 225 -----NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQ 278 I+ IV A G T + G +V VP +R+ N ++ Sbjct: 182 GAKKHRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEENAGWK 238 Query: 279 DTSKVLAVSRVMVAWQPIGISMGIYDMCHRYL-KERKQFGAPLAAFQLNQQKLVQMLGNV 337 + L R VA G + + G L + Q L ++ Sbjct: 239 LVTNQLNHER--VALVSPAPIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLARVHAKA 296 Query: 338 QAMFLMGWRLCKL----YETGQMTPGQASLGKAWISSKARETASLGRELLGGN------- 386 + + L+ W L + G +P AS K + + A E L E+LG Sbjct: 297 EVLKLINWELASSQSGPKDAG-PSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNS 355 Query: 387 -GILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGI 425 G L V + + GT ++ + G G+ Sbjct: 356 PGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMVALGL 395 >1R2J-A nrPDB Length = 366 Score = 247 bits (631), Expect = 7e-66, Method: Composition-based stats. Identities = 77/354 (21%), Positives = 139/354 (39%), Gaps = 7/354 (1%) Query: 78 MTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGLSITANAIATAEIARVDASCSTFI 136 E+ E P + +LGA G+ + +G GL N TA + + +S + + Sbjct: 16 AAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVM 75 Query: 137 LVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG 196 + T+ G Q+ +L L +A +E GSD S + T Sbjct: 76 TSQ-GMAAWTVQRLGDAGQRATFLKELTSG-KLAAVGFSERQAGSDLSAMRTRVRLDGDT 133 Query: 197 WKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNG 256 ++G K W + +AD L++F + +V D PG++ ++P G R + Sbjct: 134 AVVDGHKVWTTAAAYADHLVVFGLQEDGSG-AVVVVPADTPGVRVERVPKPSGCRAAGHA 192 Query: 257 DILLQNVFVPDEDRLPGVNSF--QDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERK 314 D+ L V VP L G + + LA R VAW +GI + + R+ Sbjct: 193 DLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAHARTRE 252 Query: 315 QFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQAS-LGKAWISSKAR 373 QFG PL QL + + Q + ++ G A+ L K + +A Sbjct: 253 QFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVAAERAA 312 Query: 374 ETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIAS 427 A+ ++L G +V +A+ D + + EG+ ++ ++ + + + Sbjct: 313 AGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHALALPA 366 >5YS9-A nrPDB Length = 708 Score = 247 bits (631), Expect = 7e-66, Method: Composition-based stats. Identities = 78/357 (21%), Positives = 131/357 (36%), Gaps = 61/357 (17%) Query: 128 VDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQ--LNTVACWALTEPDNGSDASG 185 VD + VH+ L M I G++ Q + ++ A C+A+TE +GS+ +G Sbjct: 114 VDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHGSNVAG 173 Query: 186 LGTTATKVEGG--WKIN-----GQKRWIGNSTF-ADLLIIFAR---NTTTNQINGFIVKK 234 L TTAT ++ + IN K WIG + A FAR + + F+V+ Sbjct: 174 LETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVVQL 233 Query: 235 D-------APGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTS------ 281 PG+ I K+G + NG I NV +P ++ L T Sbjct: 234 RDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPP 293 Query: 282 ------KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGA-------PLAAFQLNQQ 328 L RV + +S + RY R+QFG + + +Q+ Sbjct: 294 LAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQR 353 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYET----------------GQMTP------GQASLGKA 366 +L+ +L AM + + Y+ G+ ++ KA Sbjct: 354 RLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGLKA 413 Query: 367 WISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVT 423 + + R+ GG+G +A+ D T+EG ++ L GR + Sbjct: 414 FTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGLI 470 >5Y9D-A nrPDB Length = 709 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 79/363 (21%), Positives = 135/363 (37%), Gaps = 66/363 (18%) Query: 126 ARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPS--LAQLNTVACWALTEPDNGSDA 183 VD S T + +H++L + +I G+ Q + ++ +A C+A+TE +GS+ Sbjct: 118 GMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNL 177 Query: 184 SGLGTTATKVEGG--WKIN-----GQKRWIGNSTF-ADLLIIFARNTTTNQING---FIV 232 GL TTAT + + IN K WIG + + + FA+ + G F+V Sbjct: 178 KGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVV 237 Query: 233 K----KDAP---GLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTS---- 281 D G+ I K+G V NG I NV +P ++ L DT Sbjct: 238 PLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTK 297 Query: 282 --------KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFG-------APLAAFQLN 326 L RV + +S + RY R+QFG + + + Sbjct: 298 PALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYH 357 Query: 327 QQKLVQMLGNVQAMFLMGWRLCKLY--------------------------ETGQMTPGQ 360 Q++L+ +L AM + K + +T ++ Sbjct: 358 QRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAAS 417 Query: 361 ASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 A + KA+ + + R+ GG+G + + D T+EG ++ L GR Sbjct: 418 AGM-KAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGR 476 Query: 421 EVT 423 + Sbjct: 477 GLV 479 >5GJ7-A nrPDB Length = 398 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 79/370 (21%), Positives = 155/370 (41%), Gaps = 26/370 (7%) Query: 52 NDLLTPEEQAIRKKVRECME--KEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GY 108 L + + + R+ + E AP E+ +FPF L A G ++ Y Sbjct: 10 EAALPADVRERLRITRDLAQAFHERAP---EHDRAGDFPFENIEDLKASGYVRWTVPVEY 66 Query: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGS--EAQKEKYLPSLAQL 166 G GLS+ + +A+ D S + I H + +L + G+ + S+ + Sbjct: 67 GGLGLSLEEMLMHQEVLAKGDGSTALAIGWHVGI-LLHLRETGAFPDELFRMVCESVVKE 125 Query: 167 NTVACWALTEPDNGSDASG--LGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTT 224 + TEP GS + G TTA KV GG++I G+K + S +++ A Sbjct: 126 GALINSCATEPATGSPSRGGKPETTAVKVPGGYRITGRKTFSTLSPALTWIMVTATVADE 185 Query: 225 NQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL----PGVNSFQDT 280 + + F+V+K+ ++ + + +G+R + DI+L++VFVP+E + PGV + + Sbjct: 186 DVVGQFLVRKED--VEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQRPGVQAERRP 243 Query: 281 SKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERK--QFGAPLAAFQLNQQKLVQMLGNVQ 338 + + + +GI++ D Y + P+A +QKL +M + Sbjct: 244 DGSGWL--LHIPACYLGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKLGEMELKLL 301 Query: 339 AMFLMGWRLCKLYETG---QMTPGQASLG--KAWISSKARETASLGRELLGGNGILADFL 393 A + + L + ++ + Q G K ++ A + L ++GG + Sbjct: 302 AARTLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGGRSLSRALP 361 Query: 394 VAKAFCDLEP 403 + + + D+ Sbjct: 362 LERYYRDVRA 371 >2FON-A nrPDB Length = 683 Score = 227 bits (578), Expect = 9e-60, Method: Composition-based stats. Identities = 83/346 (23%), Positives = 134/346 (38%), Gaps = 63/346 (18%) Query: 135 FILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVE 194 F +H + + I G++ Q+EK+LP ++ + C+A TE +GS+ GL TTAT Sbjct: 117 FTDLHWGMFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDP 176 Query: 195 -------GGWKINGQKRWIGN-STFADLLIIFARNTTTN---QINGFIVK-------KDA 236 + K W G + +++AR T +NGFIV+ K Sbjct: 177 QTDEFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPL 236 Query: 237 PGLKATKIPNKIG---LRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSK----------- 282 PG+ I K G + NG + +V +P + L V+ K Sbjct: 237 PGVTVGDIGMKFGNGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLL 296 Query: 283 ---VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFG-------APLAAFQLNQQKLVQ 332 ++ V + +VA + +S + + RY R+QFG + ++ Q +L Sbjct: 297 YGTMVYVRQSIVADASLAMSRAVC-IATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFP 355 Query: 333 MLGNVQAMFLMGWRLCKLY----------------ETGQMTPGQASLGKAWISSKARETA 376 +L + A +G L LY E T G SL + + E Sbjct: 356 LLASAYAFRFVGEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEEC- 414 Query: 377 SLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 R+L GG+G L + + F P TYEG + L R + Sbjct: 415 ---RKLCGGHGYLCSSGLPELFAVYVPACTYEGDNVVLQLQVARFL 457 >1W07-A nrPDB Length = 659 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 79/346 (22%), Positives = 131/346 (37%), Gaps = 63/346 (18%) Query: 135 FILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVE 194 ++ +H + + I G+E Q++K+L ++ + C+A TE +GS+ GL TTAT Sbjct: 98 YVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDP 157 Query: 195 -------GGWKINGQKRWIGN-STFADLLIIFARNTTTN---QINGFIVKKDA------- 236 K W G + +++AR T I+GFIV+ + Sbjct: 158 KTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPL 217 Query: 237 PGLKATKIPNKIG---LRMVQNGDILLQNVFVPDEDRLPGVNSF--------QDTSKVLA 285 P + I K+G + NG ++ +V +P + L ++ D K L Sbjct: 218 PNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLV 277 Query: 286 VS------RVMVAWQPIGISMGIYDMCHRYLKERKQFG-------APLAAFQLNQQKLVQ 332 + +VA +S + + RY R+QFG + ++ Q +L Sbjct: 278 YGTMVYVRQTIVADASNALSRAVC-IATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 Query: 333 MLGNVQAMFLMGWRLCKLY----------------ETGQMTPGQASLGKAWISSKARETA 376 +L + A +G L LY E T G SL + E Sbjct: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEEC- 395 Query: 377 SLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 R+L GG+G L + + F P TYEG + L R + Sbjct: 396 ---RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 >5EZ3-A nrPDB Length = 573 Score = 217 bits (553), Expect = 7e-57, Method: Composition-based stats. Identities = 57/325 (17%), Positives = 119/325 (36%), Gaps = 25/325 (7%) Query: 118 NAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEA-QKEKY----LPSLAQLNTVACW 172 A E + T + + + + S A KY P+ + Sbjct: 152 YLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGM 211 Query: 173 ALTEPDNGSDASGLGTTATK-VEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFI 231 +TE G+D T A + G W++ G K ++ + +D + A+ ++ F+ Sbjct: 212 GMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMS-APMSDAFLTLAQT--KEGLSCFL 268 Query: 232 VKK-----DAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLA 285 + + ++ G ++ +K+G R + ++ + + ++ Sbjct: 269 LPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGAL---GQMIGSPGEGVKTIMDMVT 325 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGW 345 ++R+ A G+ + + R FG PL L Q+ L M +V + Sbjct: 326 LTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSM 385 Query: 346 RLCKLYETGQMTPGQASLG-------KAWISSKARETASLGRELLGGNGILADFLVAKAF 398 RL + ++ +A+ K W+ A E LGGNG + D +A+A+ Sbjct: 386 RLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAY 445 Query: 399 CDLEPIYTYEGTYDINTLVTGREVT 423 + +EG+ ++ L R ++ Sbjct: 446 REAPVNAIWEGSGNVMALDVARVLS 470 >3MKH-A nrPDB Length = 438 Score = 214 bits (544), Expect = 7e-56, Method: Composition-based stats. Identities = 79/403 (19%), Positives = 139/403 (34%), Gaps = 41/403 (10%) Query: 49 YHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEK---AEFPFHITPKLGAMGVAGGSI 105 + L+ ++ + R + P Y + + F T A V+ G + Sbjct: 1 MAIDFHLSASQKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGIL 60 Query: 106 KG-----YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYL 160 KG +G G ++ +AI E V+ S + I + LG+ I L E Sbjct: 61 KGQISPAHGGTGGTLIESAILVEECYSVEPSAALTIFA-TGLGLTPINLAAGPQHAEFLA 119 Query: 161 PSLA-QLNTVACWALTEPDNGSDA-----SGLGTTATKVEGGWKINGQKRWIGNST---- 210 P L+ + + +A +EP ++A G TTA W ING+K W N Sbjct: 120 PFLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARLEGDEWVINGEKMWATNCAGWDF 179 Query: 211 -FADLLIIFARN---------TTTNQINGFIVKK---DAPGLKATKIPNKI---GLRMVQ 254 DL + R+ N++ +V + D G + ++ + G V Sbjct: 180 KGCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTSVS 239 Query: 255 NGDILLQNVFVPDEDRL-PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKER 313 + NV VP ++ L P + S V+V +G+ +D ++ KE Sbjct: 240 GPHVRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKED 299 Query: 314 KQFGA-PLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMT----PGQASLGKAWI 368 + GA PL Q L + +A + W+ E G A K + Sbjct: 300 NRGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAAKVFC 359 Query: 369 SSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTY 411 S A + + +G + + + ++G Sbjct: 360 SEAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGN 402 >4Y9J-A nrPDB Length = 593 Score = 202 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 66/333 (19%), Positives = 134/333 (40%), Gaps = 33/333 (9%) Query: 117 ANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTE 176 + + + +A D + T +SL + +EA ++ + +TE Sbjct: 138 SAGLVSCPMAMTDGAVKTL----TSLNLYGKHKLATEA-VDRLRSRDPSKAWTSGQWMTE 192 Query: 177 PDNGSD-ASGLGTTATKVE-GGWKINGQKRWIGNSTFADLLIIFAR--------NTTTNQ 226 GSD A G T A +++ ++++G K W ++ AD+ + AR + Sbjct: 193 KKGGSDVAGGCDTYAVQIDKDTYRLHGYK-WFSSAVDADVALTLARIVDSDGNALEGSRG 251 Query: 227 INGFIVK-----KDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTS 281 ++ F++K + G++ ++ NK+G + + ++LL E S Sbjct: 252 LSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAI--AERIGDQGRGVAGIS 309 Query: 282 KVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMF 341 +L ++R+ A +G I + Y +R FG + + L+ L +M + + Sbjct: 310 NMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSM 369 Query: 342 LMGWRLCKL---YETGQMTPGQASLG-------KAWISSKARETASLGRELLGGNGILAD 391 L+ + +L E G+ + +A + K + +A S G E GG G + D Sbjct: 370 LLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMED 429 Query: 392 FLVAKAFCDLEPIYTYEGTYDINTLVTGREVTG 424 + D + +EGT ++ +L R +G Sbjct: 430 TGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSG 462 >2C12-A nrPDB Length = 439 Score = 188 bits (477), Expect = 5e-48, Method: Composition-based stats. Identities = 75/405 (18%), Positives = 139/405 (34%), Gaps = 45/405 (11%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEY----WEKAEFP--FHITPKLGAMGVAGGS 104 + L+P + R+ + + EY + + F + G+ Sbjct: 2 VDFKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKAQ 61 Query: 105 IK-GYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSL 163 + G S+ +I E+ V+ + S I V ++LG++ + LC S + +EK+L Sbjct: 62 VPIPLGGTMESLVHESIILEELFAVEPATSITI-VATALGLMPVILCDSPSLQEKFLKPF 120 Query: 164 AQLN--TVACWALTEPDNGSD-----ASGLGTTATKVEGGWKINGQKRWIGNST-----F 211 +A +EP+ ++ GL TTA KV W I+G+K W NS Sbjct: 121 ISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGEKLWPSNSGGWDYKG 180 Query: 212 ADLLIIFARNTTTN------------QINGFIVKKDA------PGLKATKIPNKIGLRMV 253 ADL + R + QI +V ++ + P G Sbjct: 181 ADLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEPELAGHITT 240 Query: 254 QNGDILLQNVFVPDEDRL--PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLK 311 VP E+ L PG+ + A+S +V IG + ++ + K Sbjct: 241 SGPHTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVGAMAIGTARAAFEEALVFAK 300 Query: 312 ERKQFG-APLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYE----TGQMTPGQASLGKA 366 + G + Q KL+ ++ L+ W+ E ++ A K Sbjct: 301 SDTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQTKI 360 Query: 367 WISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTY 411 + + A E + +G D + ++ ++G Sbjct: 361 YTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGN 405 >3U33-A nrPDB Length = 541 Score = 187 bits (476), Expect = 6e-48, Method: Composition-based stats. Identities = 48/279 (17%), Positives = 105/279 (37%), Gaps = 19/279 (6%) Query: 157 EKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG-WKINGQKRWIGNSTFADLL 215 LP + + +TE GSD T A ++E G +++ G K + +D Sbjct: 167 SHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS-VPQSDAH 225 Query: 216 IIFARNTTTNQINGFIVKKDAPG-----LKATKIPNKIGLRMVQNGDILLQNVFVPDEDR 270 ++ A+ ++ F V + P ++ ++ +K+G R + ++ Q+ Sbjct: 226 LVLAQTAG--GLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAI---GWL 280 Query: 271 LP-GVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQK 329 L + K+ ++R A + + + + +R FG PL L + Sbjct: 281 LGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLMRHV 340 Query: 330 LVQMLGNVQAMFLMGWRLCKLYETGQMTPGQ------ASLGKAWISSKARETASLGRELL 383 L +M ++ + +RL + ++ K I + + E+L Sbjct: 341 LSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFVAEAMEVL 400 Query: 384 GGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREV 422 GG G + + + + ++ +EG+ +I L R + Sbjct: 401 GGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVL 439 >4X28-D nrPDB Length = 373 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 71/384 (18%), Positives = 125/384 (32%), Gaps = 28/384 (7%) Query: 51 FNDLLTPEEQAIRKKVRECMEKEVAP-IMTEYWEKAE-FPFHITPKLGAMGVAG-GSIKG 107 + T Q + V ++ P E + + F + KL G+ + + Sbjct: 1 MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPES 60 Query: 108 YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 G G + + A+ V L +A GS ++ + S + Sbjct: 61 LGGDGFGVLEQVAVLVALGHQLAAVPYLESV--VLAAGALARFGSPELQQGWGVSAVSGD 118 Query: 168 TVACWAL-TEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ 226 + AL E G A G+++ G + +G AD ++ A + Sbjct: 119 RILTVALDGEMGEG------PVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAA 172 Query: 227 INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAV 286 + F+V PG+ T + GL V G + L V R+ G + + + Sbjct: 173 V--FLVAAGDPGVAVTALATT-GLGSV--GHLELNGAKVDAARRVGGTDVAVWLGTLSTL 227 Query: 287 SRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWR 346 SR +G+ M Y + R+QF P+ +FQ Q+L +V+ + L + Sbjct: 228 SRT---AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQ 284 Query: 347 LCKL--------YETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAF 398 E Q + W + A + GG G+ D V + F Sbjct: 285 AAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYF 344 Query: 399 CDLEPIYTYEGTYDINTLVTGREV 422 + G GRE+ Sbjct: 345 LAAKQTEFALGGATGQLRRIGREL 368 >4JEK-A nrPDB Length = 453 Score = 174 bits (442), Expect = 6e-44, Method: Composition-based stats. Identities = 78/390 (20%), Positives = 129/390 (33%), Gaps = 46/390 (11%) Query: 55 LTPEEQAIR----------KKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGS 104 L+PE+Q +R R EK A E L A G+ Sbjct: 39 LSPEKQHVRPRDAADNDPVAVARGLAEKWRA-TAVERDRAGGSATAEREDLRASGLLSLL 97 Query: 105 IK-GYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSL 163 + YG G EIA D S H + + I L GS+ Q+E + Sbjct: 98 VPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLTNAPM-IELIGSQEQEEHLYTQI 156 Query: 164 AQLNTVACWALTEPDNGSDASGLGTTATK-VEGGWKINGQKRWIGNSTFADLLIIFARNT 222 AQ N A +E N S +AT +GG+ +NG K + + +DLL +F Sbjct: 157 AQNNWWTGNASSE--NNSHVLDWKVSATPTEDGGYVLNGTKHFCSGAKGSDLLFVFGVVQ 214 Query: 223 TTNQINGFIVKKDAP----GLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQ 278 + G I+ P G+ IG+R +G NV V ++ L N+F Sbjct: 215 DDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDFHNVKVEPDEVLGAPNAFV 274 Query: 279 DTSKVLAVS-------RVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLN----- 326 +++ A +GI+ G D Y + + + P Q Sbjct: 275 LAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREYTRTQARPWTPAGIQQATEDPYT 334 Query: 327 -----QQKLV-QMLGNVQAMFLMGWRLCKLY-------ETGQMTPGQASLGKAWISSKAR 373 + + Q + + G++ S KA ++ A Sbjct: 335 IRSYGEFTIALQGADAAAREAAHLLQTVWDKGDALTPEDRGELMVK-VSGVKALATNAAL 393 Query: 374 ETASLGRELLGGNGILADFLVAKAFCDLEP 403 +S E++G G + + + ++ Sbjct: 394 NISSGVFEVIGARGTHPRYGFDRFWRNVRT 423 >1IS2-A nrPDB Length = 661 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 73/342 (21%), Positives = 117/342 (34%), Gaps = 55/342 (16%) Query: 136 ILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVE- 194 + +H + + T+ + Q+E++ L +A TE +G+ GL TTAT Sbjct: 100 LDLHLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPK 159 Query: 195 ------GGWKINGQKRWIGN-STFADLLIIFARNTTTN---QINGFIVK-------KDAP 237 + K W G ++ I+ A+ T ++ F+V K P Sbjct: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLP 219 Query: 238 GLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-------FQDTSKVLAVS--- 287 G+ I K G + NG + + N +P E+ L + S L Sbjct: 220 GITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMV 279 Query: 288 --R---VMVAWQPIGISMGIYDMCHRYLKERKQF------GAP-LAAFQLNQQKLVQMLG 335 R V A Q + + RY R+Q P + FQ Q KL +L Sbjct: 280 FVRSFLVGNAAQSL---SKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLA 336 Query: 336 NVQAMFLMGWRLCKLYETGQMTPGQASLG------------KAWISSKARETASLGRELL 383 A +G + + Y + GQ L KA+ + A R Sbjct: 337 TAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMAC 396 Query: 384 GGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGI 425 GG+G + + P T+EG + L T R + I Sbjct: 397 GGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKI 438 >5XDD-A nrPDB Length = 414 Score = 167 bits (424), Expect = 7e-42, Method: Composition-based stats. Identities = 71/390 (18%), Positives = 123/390 (31%), Gaps = 34/390 (8%) Query: 49 YHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSI-KG 107 H N E+ E + + E P + G+ I K Sbjct: 4 IHANSSAVREDHRALDVATELAKTFRV-TVRERERAGGTPKAERDAIRRSGLLTLLISKE 62 Query: 108 YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 G G S A AEIA DAS H S + L S QK ++ P + Sbjct: 63 RGGLGESWPTVYEAIAEIASADASLGHLFGYHFSNFAY-VDLFASPEQKARWYPQAVRER 121 Query: 168 TVACWALTEPDNGSDASGLGTTATKVEGG-WKINGQKRWIGNSTFADLLIIFARN----T 222 A +E + TAT + G ++ING K + S AD L++FA Sbjct: 122 WFLGNASSENNA--HVLDWRVTATPLPDGSYEINGTKAFCSGSADADRLLVFAVTSRDPN 179 Query: 223 TTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSK 282 +I ++ D G++ + +G+R +G + V V ++ L D Sbjct: 180 GDGRIVAALIPSDRAGVQVNGDWDSLGMRQTDSGSVTFSGVVVYPDELLGTPGQVTDAFA 239 Query: 283 VL-------AVSRVMVAWQPIGISMGIYDMCHRYLKERK-----QFGAPLAAFQLN---- 326 +++++ +GI+ G + Y + Sbjct: 240 SGSKPSLWTPITQLIFTHLYLGIARGALEEAAHYSRSHSRPFTLAGVEKATEDPYVLAIY 299 Query: 327 QQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPG-------QASLGKAWISSKARETASLG 379 + Q+ + R+ +L+E +TP Q + K + E S Sbjct: 300 GEFAAQLQVAEAGAREVALRVQELWERNHVTPEQRGQLMVQVASAKIVATRLVIELTSRL 359 Query: 380 RELLGGN-GILADFLVAKAFCDLEPIYTYE 408 E +G F + + D ++ Sbjct: 360 YEAMGARAAASRQFGFDRFWRDARTHTLHD 389 >5K3G-A nrPDB Length = 684 Score = 160 bits (406), Expect = 9e-40, Method: Composition-based stats. Identities = 67/346 (19%), Positives = 117/346 (33%), Gaps = 51/346 (14%) Query: 133 STFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK 192 + +H + + + S+ Q+ K+L + + +A TE +G++ L TTAT Sbjct: 110 GNPMALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATY 169 Query: 193 VEG-------GWKINGQKRWIGN-STFADLLIIFARN---TTTNQINGFIVK-------K 234 G KI K W GN ++ ++ A + F+V K Sbjct: 170 DIGTQEFVLHTPKITALKWWPGNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHK 229 Query: 235 DAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSF------------QDTSK 282 PG+ I K+ +V NG + N +P + L + Sbjct: 230 PLPGITIGDIGPKMAYNIVDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYS 289 Query: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGA--------PLAAFQLNQQKLVQML 334 + R + + ++ RY R+Q G + +Q Q +L + Sbjct: 290 AMVHVRSYMLTGQAIMLSYALNIATRYSAVRRQ-GQIDKNEPEVKVLEYQTQQHRLFPFI 348 Query: 335 GNVQAMFLMGWRLCKLYET--GQMTPGQASLG----------KAWISSKARETASLGREL 382 A G KLYE +M G SL K+ ++ + E R Sbjct: 349 ARAYAFQFAGAETVKLYERVLKEMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMA 408 Query: 383 LGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASF 428 GG+G +++ + TYEG + L R + A+ Sbjct: 409 CGGHGYSMASYISEIYGVAIGGCTYEGENMVMLLQLARYLVKSAAL 454 >5K3J-A nrPDB Length = 674 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 63/342 (18%), Positives = 110/342 (32%), Gaps = 53/342 (15%) Query: 133 STFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK 192 +H +L + T+ S+ Q+EK+L + + C+A TE +GS+ L TTA Sbjct: 108 GHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVY 167 Query: 193 VE-------GGWKINGQKRWIGN-STFADLLIIFARNTTTN---QINGFIVKKDAP---- 237 K W G + ++ A + F+V+ Sbjct: 168 DIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHI 227 Query: 238 ---GLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSF------------QDTSK 282 G+ I K+ NG + L N+ VP + L + Sbjct: 228 PLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAKIGYS 287 Query: 283 VLAVSRVMVAW-QPIGISMGIYDMCHRYLKERKQFGA--------PLAAFQLNQQKLVQM 333 + R +A Q + ++ + RY R+Q G + +Q Q +L Sbjct: 288 GMVKIRSQMAMEQGLFLAH-ALTIAARYSAVRRQ-GHLDDKQVEVKVLDYQTQQHRLFPS 345 Query: 334 LGNVQAMFLMGWRLCKLY-------ETGQMTP-----GQASLGKAWISSKARETASLGRE 381 L A G+ LY + G + S K+ ++ + E R Sbjct: 346 LARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIEQARM 405 Query: 382 LLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVT 423 GG+G ++ + TY G + L R + Sbjct: 406 ACGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLV 447 >4ZYJ-A nrPDB Length = 425 Score = 147 bits (371), Expect = 8e-36, Method: Composition-based stats. Identities = 68/368 (18%), Positives = 128/368 (34%), Gaps = 28/368 (7%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG-YGCPGL- 113 TP + + + + A + +A P H+ ++ GV G ++ G G+ Sbjct: 43 TPAGRRLLDLLERYLPALEA-ESRDNDREATLPVHLFDRMRKEGVLGATVPEDLGGLGVH 101 Query: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTI--ALCGSE---AQKEKYLPSLAQLNT 168 S+ A+A A IA DA + + + S G+ G+ E L + Sbjct: 102 SLHDVALALARIAGRDAGVALALHMQFSRGLTLDFEWRHGAPSTRPLAEDLLRQMGAGEA 161 Query: 169 VACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ-- 226 V C D G +G +++NG+K + + A ++ R Sbjct: 162 VIC------GAVKDVRGTTVLTRATDGSYRLNGRKTLVSMAGIATHYVVSTRLEEAGAPV 215 Query: 227 -INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLA 285 + +V + PGL + +G+R + DI+ V + LP L Sbjct: 216 RLAAPVVARTTPGLTVLDNWDGMGMRSSGSVDIVFDGCPVDRDRVLPRGEPGVRDDAAL- 274 Query: 286 VSRVMVAWQPIGISMGIYDMCHRYLKE--RKQFGAPLAAFQLNQQ---KLVQMLGNVQAM 340 + + + +GI +GI + R R++ GAP + +L + V + Sbjct: 275 AGQTVSSIAMLGIYVGIAEAARRIALTELRRRGGAPAGVRTTVAEIDARLFALHTAVASA 334 Query: 341 FLMGWRLCKLYETGQMTPGQASL-----GKAWISSKARETASLGRELLGGNGILADFLVA 395 RL G+A + K ++ + L+GG G +A Sbjct: 335 LTTADRLADDLSGDLAARGRAMMTPFQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLA 394 Query: 396 KAFCDLEP 403 + + D+ Sbjct: 395 RLYRDVRA 402 >4XVX-A nrPDB Length = 389 Score = 142 bits (358), Expect = 3e-34, Method: Composition-based stats. Identities = 67/365 (18%), Positives = 130/365 (35%), Gaps = 15/365 (4%) Query: 66 VRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLS-ITANAIATAE 124 + E+ VA E + FP + LG GV P + + A A + Sbjct: 18 AKAFDERVVA-WTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQ 76 Query: 125 IARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDAS 184 +A + +H S + + G + V C +E GSD Sbjct: 77 LASAGIGVG--VSLHDS-AIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQ 133 Query: 185 GLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQIN----GFIVKKDAPGLK 240 + T +GG+++ G K+++ S AD +++ AR+ + + +V A + Sbjct: 134 IVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVS 193 Query: 241 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVN-SFQDTSKVLAVSRVMVAWQPIGIS 299 K+G + + + + +VP + + S LA R+ +A Q Sbjct: 194 VQTPYRKVGAGPLDTAAVCI-DTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASC 252 Query: 300 MGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPG 359 + + R+QFG L Q + ++ + V + + E G++ Sbjct: 253 QRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIA---EQGRLELR 309 Query: 360 QASLGKAWISSKARETASLGRELLGGNGIL-ADFLVAKAFCDLEPIYTYEGTYDINTLVT 418 A+ K + E S + GG G L + + K + D++ GT ++ + Sbjct: 310 TAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELV 369 Query: 419 GREVT 423 +T Sbjct: 370 AAGMT 374 >3M9V-A nrPDB Length = 439 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 71/360 (19%), Positives = 121/360 (33%), Gaps = 37/360 (10%) Query: 73 EVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGLSIT-ANAIATAEIARVDA 130 + E+ FP L G+ G ++ G G+ A+A +AR DA Sbjct: 37 RIRSTAAEHDRDGTFPTDTFDALRKDGLMGATVPAELGGLGVDRLYDVAVALLAVARADA 96 Query: 131 SCSTFILVHSS--LGMLTIALCGSEA---QKEKYLPSLAQLNTVACWALTEPDNGSDASG 185 S + + + S L + G E E+ L + + V C + D Sbjct: 97 STALALHMQLSRGLTLGYEWRHGDERARTLAERILRGMVAGDAVVCSGI------KDHHT 150 Query: 186 LGTTATKVE-GGWKINGQKRWIGNSTFADLLIIFARNTTTNQ---INGFIVKKDAPGLKA 241 TT GGW ++G+K + + +I AR T+ + +V +D PG Sbjct: 151 AVTTLRPDGAGGWLLSGRKTLVSMAPVGTHFVINARTDGTDGPPRLASPVVTRDTPGFTV 210 Query: 242 TKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVL---AVSRVMVAWQPIGI 298 + +G+R DI+ + +P + L VL VS V V +G+ Sbjct: 211 LDNWDGLGMRASGTVDIVFDDCPIPADHVLMRDPVGARNDAVLAGQTVSSVSVLGVYVGV 270 Query: 299 SMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYET----- 353 + YD ER+ AA L ++ + A+ + Sbjct: 271 AQAAYDTAVA-ALERRPEPPQAAALTLV----AEIDSRLYALRATAGSALTAADALSADL 325 Query: 354 -------GQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYT 406 G+ K ++ A E S L+GG A +A+ D++ Sbjct: 326 SGDMDERGRQMMRHFQCAKLAVNRLAPEIVSDCLSLVGGASYTAGHPLARLLRDVQAGRF 385 >3MXL-A nrPDB Length = 395 Score = 138 bits (347), Expect = 5e-33, Method: Composition-based stats. Identities = 66/358 (18%), Positives = 123/358 (34%), Gaps = 39/358 (10%) Query: 73 EVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGLSIT-ANAIATAEIARVDA 130 ++ + FP + +G+ G ++ G GL+ A A +A DA Sbjct: 26 RISAEAADRDRTGTFPVEAFEQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAEADA 85 Query: 131 SCSTFILVHSSLGMLTIAL--CGSE---AQKEKYLPSLAQLNTVACWALTEPDNGSDASG 185 S + V S G+ G+ A E+ L ++A+ C AL DA G Sbjct: 86 STALAWHVQLSRGLTLTYEWQHGTPPVRAMAERLLRAMAEGEAAVCGAL------KDAPG 139 Query: 186 LGTTATKVE-GGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFI----VKKDAPGLK 240 + T GGW ++G+K + + A + A+ + + F+ V +DAPGL Sbjct: 140 VVTELHSDGAGGWLLSGRKVLVSMAPIATHFFVHAQRRDDDG-SVFLAVPVVHRDAPGLT 198 Query: 241 ATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVL---AVSRVMVAWQPIG 297 + +G+R +++ V ++ L VL VS + + G Sbjct: 199 VLDNWDGLGMRASGTLEVVFDRCPVRADELLERGPVGARRDAVLAGQTVSSITMLGIYAG 258 Query: 298 ISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYET---- 353 I+ D+ + R G P A + + + + A+ + Sbjct: 259 IAQAARDIAVGFCAGR--GGEPRA---GARALVAGLDTRLYALRTTVGAALTNADAASVD 313 Query: 354 --------GQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEP 403 G+ K ++ A L+GG A +++ + D+ Sbjct: 314 LSGDPDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVRA 371 >2RFQ-A nrPDB Length = 394 Score = 96.2 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 56/373 (15%), Positives = 119/373 (31%), Gaps = 64/373 (17%) Query: 74 VAPIMTEYWEKAE----FPFHITPKLGAMGVAGG-SIKGYGCPGLSITANAIATAEIARV 128 + P + E ++ E P L G + +G A +IA Sbjct: 19 LLPTLRERAQETEDLRRIPDDSMKALQETGFFRLLQPEQWGGYQADPVLFYSAVRKIASA 78 Query: 129 DASCS---TFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASG 185 S + I VH+ +AL +AQ++ + N +D Sbjct: 79 CGSTGWVSSIIGVHN----WHLALFSQQAQEDVW------------------GNDTDVRI 116 Query: 186 LGTTA-----TKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ---INGFIVKKDAP 237 + A V+GG+ +NG W A ++ + F++ ++ Sbjct: 117 SSSYAPMGAGQVVDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVDFVSFLIPRED- 175 Query: 238 GLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL----------PGVNSFQDTSKVLAVS 287 + + N +GLR + +++++VFVP L PG+ + Sbjct: 176 -YRIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVYKMPWG 234 Query: 288 RVM---VAWQPIGISMGIYDMCHRY--LKERKQF-GAPLAAFQLNQQKLVQMLGNVQAM- 340 + ++ +G++ G YD + + R F G + ++ + ++ A Sbjct: 235 TIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSDIDAAW 294 Query: 341 FLMGWRLCKLYE---TGQMTPGQ----ASLGKAWISSKARETASLGRELLGGNGILADFL 393 + + Y G+ P + A + + +A + E G + Sbjct: 295 RQLSGNVADEYALLVAGEEVPFELRLRARRDQVRATGRAISSIDKLFESSGATALANGTP 354 Query: 394 VAKAFCDLEPIYT 406 + + + D Sbjct: 355 LQRFWRDAHAGRV 367 >2JBS-A nrPDB Length = 422 Score = 88.5 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 64/387 (16%), Positives = 128/387 (33%), Gaps = 55/387 (14%) Query: 73 EVAPIMTEYWEKAEFPFHITPKLGAMGVAGG-SIKGYGCPGLSITANAIATAEIARVDAS 131 ++A + P L +G+ K YG +S+ A +A A Sbjct: 50 QIAKNAESAEQLRRVPDENIKLLKEIGLHRAFQPKVYGGLEMSLPDFANCIVTLAGACAG 109 Query: 132 CS---TFILVHSSLGMLTIALCGSEAQKEKYL--PSLAQLNTVACWALTEPDNGSDASGL 186 + + + HS IA+ + Q E +L P +++A + E Sbjct: 110 TAWAFSLLCTHS----HQIAMFSKQLQDEIWLKDPDATASSSIAPFGKVE---------- 155 Query: 187 GTTATKVEGGWKINGQKRWIGNSTFADLLII-FAR-NTTTNQINGF-IVKKDAPGLKATK 243 +VEGG +NG W A+ I+ F R + N+I F ++ + + Sbjct: 156 -----EVEGGIILNGDYGWSSGCDHAEYAIVGFNRFDADGNKIYSFGVIPRSD--YEIVD 208 Query: 244 IPNKIGLRMVQNGDILLQNVFVPD-------EDRLPGVNSFQ---DTSKVLAVSRV---- 289 ++ + + L NVF+P+ + F D+ R Sbjct: 209 NWYAQAIKSSGSKMLKLVNVFIPEYRISKAKDMMEGKSAGFGLYPDSKIFYTPYRPYFAS 268 Query: 290 MVAWQPIGISMGIYDMCHRYLKERKQ--FGAPLAAFQLNQQKLVQMLGNVQAMFLM---G 344 + +GI+ + + + R + GA + ++ + V A + Sbjct: 269 GFSAVSLGIAERMIEAFKEKQRNRVRAYTGANVGLATPALMRIAESTHQVAAARALLEKT 328 Query: 345 WRLCKLYETGQMTPGQASLG-----KAWISSKARETASLGRELLGGNGILADFLVAKAFC 399 W +++ P + +L +A+ E G + + + + F Sbjct: 329 WEDHRIHGLNHQYPNKETLAFWRTNQAYAVKMCIEAVDRLMAAAGATSFMDNSELQRLFR 388 Query: 400 DLEPIYTYEGTY-DINTLVTGREVTGI 425 D + T D+ + GRE+ G+ Sbjct: 389 DAHMTGAHAYTDYDVCAQILGRELMGM 415 >3AFF-A nrPDB Length = 394 Score = 84.2 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 52/369 (14%), Positives = 116/369 (31%), Gaps = 56/369 (15%) Query: 74 VAPIMTEYWEKAE----FPFHITPKLGAMGVAGG-SIKGYGCPGLSITANAIATAEIARV 128 + P + + + E P L +G + +G AT +A V Sbjct: 19 LLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASV 78 Query: 129 DASCS---TFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEP-DNGSDAS 184 S + + VH+ +AL AQ+E + + +A P G Sbjct: 79 CGSTGWVSSIVGVHN----WHLALFDQRAQEEVWGED-PSTRISSSYA---PMGAG---- 126 Query: 185 GLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQ---INGFIVKKDAPGLKA 241 V+GG+ +NG W A + + F++ + + Sbjct: 127 ------VVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSE--YEI 178 Query: 242 TKIPNKIGLRMVQNGDILLQNVFVPDEDRL----------PGVNSFQDTSKVLAVSRVM- 290 + +GLR + +++++VFVP L G+ + + + Sbjct: 179 KDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHP 238 Query: 291 --VAWQPIGISMGIYDMCHRY--LKERKQF-GAPLAAFQLNQQKLVQMLGNVQAM-FLMG 344 ++ +G++ G Y + + R F G + ++ + ++ A + Sbjct: 239 TTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAWRQLI 298 Query: 345 WRLC---KLYETGQMTPGQ----ASLGKAWISSKARETASLGRELLGGNGILADFLVAKA 397 + L G+ P + A + + ++ + E G + + + + Sbjct: 299 GNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRF 358 Query: 398 FCDLEPIYT 406 + D Sbjct: 359 WRDAHAGRV 367 >5LVW-A nrPDB Length = 413 Score = 80.0 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 50/399 (12%), Positives = 108/399 (27%), Gaps = 59/399 (14%) Query: 38 ASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGA 97 +S P S + ++V + A + E + P + Sbjct: 7 SSGLVPRGSHMTDIRSETAELRAELVERVHKFG-PVFADGVAEGERERRLPDATVRAIDQ 65 Query: 98 MGV-AGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQK 156 + + K YG + + ++ S S + + GS Sbjct: 66 SQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVN----------NVNGSNLLA 115 Query: 157 EKYLPSLAQLNTVACWALTEPDNG-SDASGLGTTATKVEGGWKINGQKRWIGNSTFADLL 215 K+ P A P + TA + GG+++ G + D Sbjct: 116 SKF-PRAALDEVFGDA----PGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWA 170 Query: 216 IIFARNTTTNQ-----INGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDR 270 I+ AR + ++ + +D L + +G+R + ++L++ FVP+ Sbjct: 171 ILVAREVDADGEPVGGLSMLVPARD---LTVEDTWHTVGMRATGSHTVVLRDTFVPEHRV 227 Query: 271 LPGV----------NSFQDTSKVLAVS--RVMVAWQPIGISMGIYDMCHRYLKER----- 313 + G + A++ V+ A +G + R Sbjct: 228 ISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPS 287 Query: 314 --------KQFGAPLAAFQLNQQKLVQMLGNVQAMFL--MGWRLCKLYETG-QMTPGQAS 362 + F + L +M A L + L ++ G Sbjct: 288 KYTRQTDSRTFVSSLGRT-ALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVG 346 Query: 363 LGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDL 401 + +++ G + + + D Sbjct: 347 QAVSLVTTA----LDELLWAHGAASFAESNPLQRYWRDA 381 >2OR0-A nrPDB Length = 414 Score = 70.4 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 34/241 (14%), Positives = 71/241 (29%), Gaps = 31/241 (12%) Query: 190 ATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQING------FIVKKDAPGLKATK 243 AT V+GG+ + G+ + + + A I+ + + Sbjct: 139 ATPVDGGYVLKGRWSFSSGTDHCQWAFLGAMVGDGEGGIATPSSLHVILPRTDYQI-VED 197 Query: 244 IPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSR--------------V 289 + IGLR + D+++ FVP L D R + Sbjct: 198 TWDVIGLRGTGSKDLIVDGAFVPGYRTL-NAAKVMDGRAQKEAGRPEPLFNMPYSCMFPL 256 Query: 290 MVAWQPIGISMGIYDMCHRYLKERKQF-GAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 + IGI+ G K+R G + + + + A + Sbjct: 257 GITAAVIGITEGALACHIAVQKDRVAITGQKIKEDPYVLSAIGESAAEINASRVSLIETA 316 Query: 349 KLY----ETGQMTP-GQASLGKAWISSKARETASLGRELL---GGNGILADFLVAKAFCD 400 + + G+ + ++G+ + A E+ GG + + + + D Sbjct: 317 DRFYDKVDAGKEITFEERAIGRRTQIAAAWRAVRAADEIFARAGGGALHYKTPMQRFWRD 376 Query: 401 L 401 Sbjct: 377 A 377 >3HWC-A nrPDB Length = 515 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 21/155 (13%), Positives = 47/155 (30%), Gaps = 22/155 (14%) Query: 159 YLPSLAQLNTVACWALTEPDN--GSDASGLGT----TATKVEGGWKINGQKRWIGNSTFA 212 +L L + + +P SDA+ + K + G +NG K F Sbjct: 138 FLKLLREKDLNCPLNFVDPQTDRSSDAAQARSPNLRIVEKTDDGIIVNGVKAVGTGIAFG 197 Query: 213 DLL---IIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQN----------GDIL 259 D + ++ Q+ + + PG+ + + ++ + Sbjct: 198 DYMHIGCLYRPGIPGEQVIFAAIPTNTPGVTVFCRESTVKNDPAEHPLASQGDELDSTTV 257 Query: 260 LQNVFVPDEDR--LPGVNSFQ-DTSKVLAVSRVMV 291 NVF+P E + + ++ + Sbjct: 258 FDNVFIPWEQVFHIGNPEHAKLYPQRIFDWVHYHI 292 >4G5E-A nrPDB Length = 517 Score = 36.9 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 39/105 (37%), Gaps = 14/105 (13%) Query: 175 TEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLL---IIFARNTTTNQINGFI 231 + PD + GL K + G ++G K FAD + + F +QI Sbjct: 162 SNPDAQQRSPGLRV-IEKNDKGIVVSGVKAIGTGVAFADWIHIGVFFRPGIPGDQIIFAA 220 Query: 232 VKKDAPGLKAT---------KIPNKIGLRMVQ-NGDILLQNVFVP 266 + PG+ I + + + + +G + NVF+P Sbjct: 221 TPVNTPGVTIVCRESVVKEDPIEHPLASQGDELDGMTVFDNVFIP 265 >2YYI-A nrPDB Length = 481 Score = 36.5 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 34/224 (15%), Positives = 61/224 (27%), Gaps = 38/224 (16%) Query: 154 AQKEKYLPSLAQLNTVACWALTEPD--------NGSDASGLGTTATKVEGGWKINGQKRW 205 Y L + ALT P D + E G + G + Sbjct: 124 ENVRNYYRYLRDQDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKGIVVRGARMT 183 Query: 206 IGNSTFADLLIIFARN----TTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDI--- 258 AD ++IF + F + PGL +G + + Sbjct: 184 ATF-PLADEVLIFPSTLLQAGSEKYALAFALPTSTPGLHFVCREALVGGDSPFDHPLSSR 242 Query: 259 --------LLQNVFVPDEDR--LPGV---NSFQDTSKVLAVSRVMVAWQPIGISMGIYDM 305 + +V VP E L V N+ + L V + + Sbjct: 243 VEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAHQVVALKTAKTEAFLGV 302 Query: 306 CHRYLKERKQFGAPLAA--FQLNQQKLVQMLGNVQAMFLMGWRL 347 + + A + Q+K+ +++ ++AM R Sbjct: 303 AALMAEG-------IGADVYGHVQEKIAEIIVYLEAMRAFWTRA 339 >4XGC-A nrPDB Length = 393 Score = 33.8 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 35/113 (30%), Gaps = 18/113 (15%) Query: 269 DRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQ 328 RL G +F+ + L +V G + D+C R + QQ Sbjct: 225 ARLGGSETFKGEAVQLVARKV---AAVSGDARRALDICRRATEIADTAAVKCVTMLHVQQ 281 Query: 329 KLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRE 381 L +M + + + R C E ++ + A E G E Sbjct: 282 ALAEM---IASAKVQAIRNCSRMEQ------------IFLQAIAAEVTRTGVE 319 >4Q0M-A nrPDB Length = 327 Score = 32.6 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 17/40 (42%), Gaps = 2/40 (5%) Query: 90 HITPKLGAMGVAGGSIKGYGCPGLSITANAIA--TAEIAR 127 I +G G I+GYG G+ + + E+++ Sbjct: 215 DIFRAAVELGYRGIVIEGYGAGGIPYRGSDLLQTIEELSK 254 >1U8V-A nrPDB Length = 490 Score = 31.5 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 34/201 (16%), Positives = 59/201 (29%), Gaps = 49/201 (24%) Query: 148 ALCGSEAQKEK--YLPSLAQLNTVACWALTEPDNGSDASGLGTTATKV-----------E 194 G+ K YL + + + + A+T+P GL +A K E Sbjct: 121 QKYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGD---RGLAPSAQKDPDLFLRIVEKRE 177 Query: 195 GGWKINGQKRWIGNSTFADLLIIF----ARNTTTNQINGFIVKKDAPGLKAT-------- 242 G + G K S + II + F DA GL Sbjct: 178 DGIVVRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVSFACPSDADGLFMIYGRQSCDT 237 Query: 243 -KIPN----KIGLRMVQNGD--ILLQNVFVPDED------------RLPGVNSFQDTSKV 283 K+ +G + + ++ NVF+P++ + + + Sbjct: 238 RKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHR--QS 295 Query: 284 LAVSRVMVAWQPIGISMGIYD 304 +V V IG + D Sbjct: 296 YGGCKVGVGDVVIGAAALAAD 316 >5VA1-A nrPDB Length = 795 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 10/117 (8%) Query: 6 SADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKK 65 SAD A+ + ++ +PP +V P P ST P LT + + Sbjct: 682 SADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPT---LTLDS---LSQ 735 Query: 66 VRECME-KEVAPIMTEYWEKAEFPFHITPKLGAMG-VAGGSIKGYGCPGLSITANAI 120 V + M +E+ P E ++ P G +G + + +G S +N++ Sbjct: 736 VSQFMACEELPPGAPELPQEG--PTRRLSLPGQLGALTSQPLHRHGSDPGSEASNSL 790 >1KA4-A nrPDB Length = 499 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 3/88 (3%) Query: 5 SSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRK 64 S A +A E K K + P + A A+ + + Y L E R Sbjct: 113 SLATKAWEEAKAKDDFSKFEPW-LDKIISLAKRAAEYLGYEEEPYDALLDLYEEGLRTRD 171 Query: 65 KVREC--MEKEVAPIMTEYWEKAEFPFH 90 + +EK++ P++ + E+ + P Sbjct: 172 VEKMFEVLEKKLKPLLDKILEEGKVPRE 199 >4HNL-A nrPDB Length = 421 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 12/100 (12%), Positives = 30/100 (30%), Gaps = 11/100 (11%) Query: 48 YYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKG 107 + D+L P++ ++R + PI T + K + + Sbjct: 249 LFFLEDILPPDQSHWLTQLRS---QSATPIATGELFNNPMEWQELVKNRQIDFMRAHVSQ 305 Query: 108 YGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTI 147 G ++ ++A + I H+ + + Sbjct: 306 IGGITPAL--------KLAHFCDAMGVRIAWHTPSDISPV 337 >2Q3R-A nrPDB Length = 372 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 11/26 (42%) Query: 366 AWISSKARETASLGRELLGGNGILAD 391 + A E G E+ G NG L D Sbjct: 166 RLAARNAMEAGFDGVEIHGANGYLID 191 >6B1B-A nrPDB Length = 527 Score = 29.9 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 21/149 (14%), Positives = 42/149 (28%), Gaps = 27/149 (18%) Query: 150 CGSEAQKEK-YLPSLAQLNTVACWALTEPDNGSDASGLGTTATKV------EGGWKINGQ 202 G Q + + + + A+ P + + G ++G Sbjct: 139 YGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHLPTDKVKDVYIKLEKETDAGIIVSGA 198 Query: 203 KRWIGNSTFADLLIIFARNTT-----TNQINGFIVKKDAPGLKATKI---PNKIGLRMVQ 254 K NS +I + + + F+ DA G+K G Sbjct: 199 KVVATNSALTHYNMIGSGSDLGSGSDPDFALMFVAPMDADGVKLISRASYEMVAGATGSP 258 Query: 255 ------------NGDILLQNVFVPDEDRL 271 + +++ NV +P E+ L Sbjct: 259 YDYPLSSRFDENDAILVMDNVLIPWENVL 287 >1ICQ-A nrPDB Length = 376 Score = 29.6 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 11/24 (45%) Query: 368 ISSKARETASLGRELLGGNGILAD 391 + A E G E+ G +G L D Sbjct: 172 AARNAIEAGFDGVEIHGAHGYLID 195 >3RMT-A nrPDB Length = 455 Score = 29.6 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 38/110 (34%), Gaps = 18/110 (16%) Query: 220 RNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQD 279 R+ T + F V + GL + ++ + Q+V VP + + F Sbjct: 197 RDHTERMLEAFGVNIEKDGLTVSIEGGQM---------LTGQHVVVPGD--ISSAAFFLV 245 Query: 280 TSKVLAVSRVMVAWQPI-----GISMGI--YDMCHRYLKERKQFGAPLAA 322 ++ SR+ + I GI + ER Q G P+A Sbjct: 246 AGAMVPHSRITLTNVGINPTRAGILEVLKQMGATLAMENERVQGGEPVAD 295 >5K1Q-A nrPDB Length = 355 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 10/24 (41%) Query: 368 ISSKARETASLGRELLGGNGILAD 391 + E G E+ G NG L D Sbjct: 167 AAENVIEAGFDGVEIHGANGYLID 190 >1G29-1 nrPDB Length = 372 Score = 28.8 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 17/42 (40%), Gaps = 3/42 (7%) Query: 248 IGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRV 289 G+R D + V VP E+ V + + + L R+ Sbjct: 287 FGIRPEDLYDAMFAQVRVPGENL---VRAVVEIVENLGSERI 325 >5LC3-A nrPDB Length = 205 Score = 28.8 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 12/31 (38%) Query: 383 LGGNGILADFLVAKAFCDLEPIYTYEGTYDI 413 GG GI + + + YEG ++ Sbjct: 163 CGGKGIKTKSPFEQHIKNNKETNKYEGWPEV 193 >5LC2-A nrPDB Length = 205 Score = 28.4 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 12/31 (38%) Query: 383 LGGNGILADFLVAKAFCDLEPIYTYEGTYDI 413 GG GI + + + YEG ++ Sbjct: 163 CGGKGIKTKSPFEQHIKNNKDTNKYEGWPEV 193 >1G21-E nrPDB Length = 289 Score = 28.4 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 35/126 (27%), Gaps = 13/126 (10%) Query: 56 TPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGV----AGGSIKGYGCP 111 P+ + R + + + + E + K G GV +GG G GC Sbjct: 40 DPKADSTRLILHSKAQNTIMEMAAEAGTVEDLELEDVLKAGYGGVKCVESGGPEPGVGCA 99 Query: 112 GLSITANAIATAEIARVDASCSTFI----LVHSSLGMLTIALCGSEAQKEKYLPSLAQLN 167 G + E + V + I K + + + Sbjct: 100 GRGVITAINFLEEEGAYEDDLDFVFYDVGDVVCGGFAMPIR-----ENKAQEIYIVCSGE 154 Query: 168 TVACWA 173 +A +A Sbjct: 155 MMAMYA 160 >6NFE-A nrPDB Length = 323 Score = 28.4 bits (62), Expect = 6.3, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 33/103 (32%), Gaps = 19/103 (18%) Query: 258 ILLQNVFV------PDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLK 311 + ++VFV P + L + D + + R+ G + + Sbjct: 56 VRGKDVFVLQSTCAPANNNLMELLIMADALRRSSAGRITAVVPYFGYAR----------Q 105 Query: 312 ERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETG 354 +R+ A + + + M+ +V ++ L G Sbjct: 106 DRRV---RSARVPITAKVVADMMASVGICRVLTVDLHADQIQG 145 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.143 0.386 Lambda K H 0.267 0.0440 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,263,340 Number of Sequences: 36641 Number of extensions: 719942 Number of successful extensions: 2470 Number of sequences better than 10.0: 99 Number of HSP's better than 10.0 without gapping: 136 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 1898 Number of HSP's gapped (non-prelim): 183 length of query: 436 length of database: 10,336,785 effective HSP length: 100 effective length of query: 336 effective length of database: 6,672,685 effective search space: 2242022160 effective search space used: 2242022160 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)