BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q96242 (518 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2RCM-A nrPDB 993 0.0 3DBM-A nrPDB 635 0.0 2VE3-A nrPDB 50 2e-06 3EL3-A nrPDB 46 4e-05 2W0A-A nrPDB 46 4e-05 5VEU-A nrPDB 46 5e-05 6DA2-A nrPDB 44 1e-04 3MZS-A nrPDB 41 0.001 5FYF-A nrPDB 41 0.001 3EJB-B nrPDB 39 0.004 3R9C-A nrPDB 39 0.004 3SN5-A nrPDB 37 0.014 4FB2-A nrPDB 37 0.017 5LIE-A nrPDB 37 0.019 3MGX-A nrPDB 37 0.025 4R20-A nrPDB 36 0.041 1UE8-A nrPDB 36 0.053 2PG7-A nrPDB 35 0.055 6AYB-A nrPDB 35 0.058 5L94-A nrPDB 35 0.063 3TBG-A nrPDB 35 0.10 4RM4-A nrPDB 35 0.11 3S79-A nrPDB 34 0.13 3BUJ-A nrPDB 33 0.28 5OFQ-A nrPDB 33 0.28 1WIY-A nrPDB 33 0.30 1F4U-A nrPDB 33 0.34 1Q5D-A nrPDB 33 0.36 1CPT-A nrPDB 33 0.40 3K9V-A nrPDB 33 0.41 6H03-D nrPDB 32 0.46 4WMZ-A nrPDB 32 0.66 5H1Z-A nrPDB 32 0.67 6F0B-A nrPDB 32 0.72 2X2N-A nrPDB 32 0.73 6HQW-A nrPDB 32 0.79 5E0E-A nrPDB 32 0.90 1WR8-A nrPDB 32 0.92 4XE3-A nrPDB 32 0.97 3P3Z-A nrPDB 31 1.0 6C94-A nrPDB 31 1.1 5VDN-A nrPDB 31 1.1 3RWL-A nrPDB 31 1.1 5M0P-A nrPDB 31 1.1 3NC3-A nrPDB 31 1.2 6DWN-A nrPDB 31 1.3 6M7X-A nrPDB 31 1.6 6G5O-A nrPDB 31 1.6 3A1L-A nrPDB 31 1.6 4YZR-A nrPDB 30 1.8 3L4D-A nrPDB 30 2.2 3TKT-A nrPDB 30 2.4 2ZQJ-A nrPDB 30 2.5 5D2Y-A nrPDB 30 2.9 6NT6-A nrPDB 30 3.5 1WKR-A nrPDB 29 4.0 5KB6-A nrPDB 29 4.2 3EB7-A nrPDB 29 4.3 5HDI-A nrPDB 29 5.0 4Q98-A nrPDB 29 6.3 5YLW-A nrPDB 28 7.4 4B9P-A nrPDB 28 9.1 3IBD-A nrPDB 28 9.2 >2RCM-A nrPDB Length = 495 Score = 993 bits (2568), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/486 (99%), Positives = 485/486 (99%) Query: 33 ASGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKY 92 +SGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKY Sbjct: 6 SSGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKY 65 Query: 93 NSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDLFTGTYMPSTELTGGYR 152 NSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDL TGTYMPSTELTGGYR Sbjct: 66 NSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDLLTGTYMPSTELTGGYR 125 Query: 153 ILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGS 212 ILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGS Sbjct: 126 ILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGS 185 Query: 213 SDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFS 272 SDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFS Sbjct: 186 SDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFS 245 Query: 273 LPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPN 332 LPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPN Sbjct: 246 LPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPN 305 Query: 333 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY 392 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY Sbjct: 306 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY 365 Query: 393 GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRH 452 GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRH Sbjct: 366 GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRH 425 Query: 453 VLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS 512 VLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS Sbjct: 426 VLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS 485 Query: 513 LRKASF 518 LRKASF Sbjct: 486 LRKASF 491 >3DBM-A nrPDB Length = 473 Score = 635 bits (1637), Expect = 0.0, Method: Compositional matrix adjust. Identities = 296/467 (63%), Positives = 375/467 (80%), Gaps = 3/467 (0%) Query: 53 PIRNIPGNYGLPIVGPIKDRWDYFYDQGA-EEFFKSRIRKYNSTVYRVNMPPGAFIAENP 111 P+R IPG+YG+P PIKDR +YFY G +E+F+SR++KY STV+R NMPPG F++ NP Sbjct: 7 PLREIPGSYGIPFFQPIKDRLEYFYGTGGRDEYFRSRMQKYQSTVFRANMPPGPFVSSNP 66 Query: 112 QVVALLDGKSFPVLFDVDKVEKKDLFTGTYMPSTELTGGYRILSYLDPSEPKHEKLKNLL 171 +V+ LLD KSFP+LFDV KVEKKDLFTGTYMPST+LTGGYR+LSYLDPSEP+H +LKNLL Sbjct: 67 KVIVLLDAKSFPILFDVSKVEKKDLFTGTYMPSTKLTGGYRVLSYLDPSEPRHAQLKNLL 126 Query: 172 FFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGSSDGTAFNFLARAFYGTNPA 231 FF+LK+S NR+ P+F+ TY+ELF+ LE EL+ GKA F + AF FL RA++ +NP Sbjct: 127 FFMLKNSSNRVIPQFETTYTELFEGLEAELAKNGKAAFNDVGEQAAFRFLGRAYFNSNPE 186 Query: 232 DTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLE 291 +TKL AP LI+ WVLFNL P L +GLP ++EPL+HTF LP L+KS Y +LY++F Sbjct: 187 ETKLGTSAPTLISSWVLFNLAPTLDLGLPWFLQEPLLHTFRLPAFLIKSTYNKLYDYFQS 246 Query: 292 SAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEE 351 A ++ +A+KLG+ ++EA HN+LFA CFNT+GG+KILFPN +K IG AG +H +LAEE Sbjct: 247 VATPVMEQAEKLGVPKDEAVHNILFAVCFNTFGGVKILFPNTLKWIGLAGENLHTQLAEE 306 Query: 352 IRSVIKSNG-GELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKV 410 IR IKS G G +T+ AIE+M LTKSVVYE LR EPPV QYG+AK + IESHDA F+V Sbjct: 307 IRGAIKSYGDGNVTLEAIEQMPLTKSVVYESLRIEPPVPPQYGKAKSNFTIESHDATFEV 366 Query: 411 KAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQ 470 K GEML+GYQP AT+DPK+FDR +E+VP+RFVG +GE LL++V WSNGPETE+PTV NKQ Sbjct: 367 KKGEMLFGYQPFATKDPKVFDRPEEYVPDRFVG-DGEALLKYVWWSNGPETESPTVENKQ 425 Query: 471 CAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSLRKAS 517 CAGKDFVVL+ RLFVIE+FRRYDSF+IE+G SPLG++V + L++AS Sbjct: 426 CAGKDFVVLITRLFVIELFRRYDSFEIELGESPLGAAVTLTFLKRAS 472 >2VE3-A nrPDB Length = 444 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 16/152 (10%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 + R+ +E + S ELT ++KM V+ E LR PPV G ++L+ + Sbjct: 276 IRERVRQEQNKLQLSQ--ELTAETLKKMPYLDQVLQEVLRLIPPV----GGGFRELIQDC 329 Query: 404 HDAAFKVKAGEMLYGYQPLATR-DPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 F G L YQ T DP ++ ++F PERF + N P Sbjct: 330 QFQGFHFPKG-WLVSYQISQTHADPDLYPDPEKFDPERFTPDGSAT-------HNPPFAH 381 Query: 463 TPTVGN-KQCAGKDFVVLVARLFVIEIFRRYD 493 P G ++C GK+F L +LF + +++D Sbjct: 382 VPFGGGLRECLGKEFARLEMKLFATRLIQQFD 413 >3EL3-A nrPDB Length = 467 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 16/155 (10%) Query: 340 AGHQVH-NRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKD 398 A H H +R+ +E+ +V + G + + K+ T +V+ E +R P V RA Sbjct: 291 ADHPEHADRIRDEVEAV--TGGRPVAFEDVRKLRHTGNVIVEAMRLRPAVWVLTRRA--- 345 Query: 399 LVIESHDAAFKVKAGEMLYGYQPLA-TRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSN 457 V ES +++ AG + Y P A RDPK +D EF P+R++ E + ++ + Sbjct: 346 -VAESELGGYRIPAGADII-YSPYAIQRDPKSYDDNLEFDPDRWLPERAANVPKYAM--- 400 Query: 458 GPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 + + G ++C F + L + +Y Sbjct: 401 ----KPFSAGKRKCPSDHFSMAQLTLITAALATKY 431 >2W0A-A nrPDB Length = 455 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 30/136 (22%), Positives = 59/136 (43%), Gaps = 12/136 (8%) Query: 359 NGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 +G ++ A+ ++ ++V+ E LR PP+ AK + ++ H ++ G+++ Sbjct: 292 DGRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGH----RIHEGDLVAA 347 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETP-TVGNKQCAGKDFV 477 ++ R P+ F +FVP R+ E LL W P G +C G F Sbjct: 348 SPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTW-------IPFGAGRHRCVGAAFA 400 Query: 478 VLVARLFVIEIFRRYD 493 ++ + + R Y+ Sbjct: 401 IMQIKAIFSVLLREYE 416 >5VEU-A nrPDB Length = 480 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 15/150 (10%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V +L +EI +V+ N T A+ +ME VV E LR P KKD+ I Sbjct: 306 VQQKLQKEIDAVL-PNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-- 362 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETET 463 + F + G M+ DPK + +EF PERF ++ S P T Sbjct: 363 -NGVF-IPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD---------SIDPYIYT 411 Query: 464 P-TVGNKQCAGKDFVVLVARLFVIEIFRRY 492 P G + C G F ++ +L +I + + + Sbjct: 412 PFGTGPRNCIGMRFALMNMKLALIRVLQNF 441 >6DA2-A nrPDB Length = 487 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 41/150 (27%), Positives = 65/150 (43%), Gaps = 14/150 (9%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V +L EEI +V+ N T + +ME VV E LR P KKD+ I Sbjct: 307 VQQKLQEEIDAVL-PNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 363 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETET 463 + F K ++ L RDPK + ++F+PERF + + + P T Sbjct: 364 -NGMFIPKGVVVMIPSYALH-RDPKYWTEPEKFLPERFSKKNKDNI--------DPYIYT 413 Query: 464 P-TVGNKQCAGKDFVVLVARLFVIEIFRRY 492 P G + C G F ++ +L +I + + + Sbjct: 414 PFGSGPRNCIGMRFALMNMKLALIRVLQNF 443 >3MZS-A nrPDB Length = 486 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 22/159 (13%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V L EE+ + + G+++ ++ + L K+ + E LR P + DLV++ Sbjct: 309 VQEMLREEVLNARRQAEGDIS-KMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQD 367 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVL---WSNGPE 460 + K +Y RDP F D+F P R++ ++ + + L W Sbjct: 368 YLIPAKTLVQVAIYA----MGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLGFGW----- 418 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEV 499 G +QC G+ L LF+I I ++F +E+ Sbjct: 419 ------GVRQCVGRRIAELEMTLFLIHIL---ENFKVEM 448 >5FYF-A nrPDB Length = 470 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 21/141 (14%) Query: 370 KMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 K EL ++V E +R++ P+ AK+D+ + +K G+ + + RD + Sbjct: 336 KPELIPNMVSEIIRWQTPLAYMRRIAKQDVELGGQ----TIKKGDRVVMWYASGNRDERK 391 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 FD D+F+ +R + H+ + G +C G L R+ EI Sbjct: 392 FDNPDQFIIDR------KDARNHMSFG---------YGVHRCMGNRLAELQLRILWEEIL 436 Query: 490 RRYDSFDIEVGTSPLGSSVNF 510 +R+D +IEV P NF Sbjct: 437 KRFD--NIEVVEEPERVQSNF 455 >3EJB-B nrPDB Length = 404 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 E +L + V ECLR+E P A +D+ I ++ GE +Y A RDP Sbjct: 262 ENPDLIGTAVEECLRYESPTQMTARVASEDIDI----CGVTIRQGEQVYLLLGAANRDPS 317 Query: 429 IFDRADEF 436 IF D F Sbjct: 318 IFTNPDVF 325 >3R9C-A nrPDB Length = 418 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 7/102 (6%) Query: 340 AGHQVH-NRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKD 398 AGH+ N +A +++++ G + A +V+ E +R++PPV A D Sbjct: 256 AGHETTVNLIANAALAMLRTPGQWAALAA--DGSRASAVIEETMRYDPPVQLVSRYAGDD 313 Query: 399 LVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPER 440 L I +H V G+ + A RDP I D F P+R Sbjct: 314 LTIGTH----TVPKGDTMLLLLAAAHRDPTIVGAPDRFDPDR 351 >3SN5-A nrPDB Length = 491 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/158 (18%), Positives = 69/158 (43%), Gaps = 16/158 (10%) Query: 349 AEEIRSVIKSNGGE---------LTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDL 399 EE++ +++ G + L+ + + + S++ E LR + AK+D Sbjct: 295 TEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSS-ASLNIRTAKEDF 353 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 + D ++ ++ +++ Y L DP+I+ F +R++ E G+ + + NG Sbjct: 354 TLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKT--KTTFYCNGL 411 Query: 460 ETETPTV----GNKQCAGKDFVVLVARLFVIEIFRRYD 493 + + + G C G+ F + + F+I + ++ Sbjct: 412 KLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFE 449 >4FB2-A nrPDB Length = 398 Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 65/175 (37%), Gaps = 30/175 (17%) Query: 324 GGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLR 383 G IL + R V RLA +I EL I EL + V E LR Sbjct: 224 GFFTILLLGGIDNTARFLSSVFWRLAWDI---------ELRRRLIAHPELIPNAVDELLR 274 Query: 384 FEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVG 443 F P A GR + E +K G+ + P+A+RD FD D V ER Sbjct: 275 FYGP--AMVGRL---VTQEVTVGDITMKPGQTAMLWFPIASRDRSAFDSPDNIVIERTPN 329 Query: 444 EEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIE 498 RH+ +G +C G + + AR+ + E +R F ++ Sbjct: 330 -------RHLSLGHGIH---------RCLGAHLIRVEARVAITEFLKRIPEFSLD 368 >5LIE-A nrPDB Length = 414 Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 EL + + E +R+ P ++ A + + + ++AG+ + ++ A RDP +FD Sbjct: 284 ELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQ----PIEAGQKVVVWEGSANRDPSVFD 339 Query: 432 RADEF 436 RADEF Sbjct: 340 RADEF 344 >3MGX-A nrPDB Length = 415 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Query: 376 SVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADE 435 +VV E LR+ P D+ I D + +G + + P A RDP FD D Sbjct: 289 TVVEEVLRWTSPAMHVLRVTTADVTINGRD----LPSGTPVVAWLPAANRDPAEFDDPDT 344 Query: 436 FVPERFVGEEGEKLLRHVLWSNG 458 F+P G K RH+ + +G Sbjct: 345 FLP-------GRKPNRHITFGHG 360 >4R20-A nrPDB Length = 486 Score = 35.8 bits (81), Expect = 0.041, Method: Compositional matrix adjust. Identities = 83/384 (21%), Positives = 148/384 (38%), Gaps = 72/384 (18%) Query: 147 LTGGYRILSYLD--PSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLK 204 LT G + +++ D P H +L + F L N++ Q E DSL +EL Sbjct: 97 LTQGGKDIAFADYSPLWKNHRRLVHSSFTLFGEGSNKL----QTIVQEAADSLCEEL--- 149 Query: 205 GKADFGGSSDGTAF------NFLARAFYGTN--PADTKLKA------DAPGLITKWVLFN 250 +A G SSD + N + R + ++ P+D +L+ I + L + Sbjct: 150 -QACRGQSSDLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTIARGGLVD 208 Query: 251 LHPLLSI----GLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEI-------LVE 299 + P L I L R+ E V Q LY+ LE + L++ Sbjct: 209 IFPWLRIFPNKDLKRLKE------------CVSIRDQLLYKKLLEHKKSLTPGEPRDLLD 256 Query: 300 ADKLGISR-----EEATHNLLFATCFNTWG-GMKILFPNMVKRIGRAGHQVHNRLAEEIR 353 A +G R ++ T + + T +G G++ ++ I H H +L E ++ Sbjct: 257 ALLIGQQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLH--HPQLQERVQ 314 Query: 354 SVIKSNGG---ELTMGAIEKMELTKSVVYECLRFEP--PVTAQYGRAKKDLVIESHDAAF 408 + + G + + L +V+ E +R P P+ + A +D + H Sbjct: 315 AELDECVGVDRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPH-VAMQDTSLGGHSVPK 373 Query: 409 KVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGN 468 + ++ DPK +D+ ++F PERF+ G+K + G G Sbjct: 374 GTRVLVNMWAIH----HDPKHWDQPEQFNPERFLEPSGKKKTQSSFLPFG-------AGP 422 Query: 469 KQCAGKDFVVLVARLFVIEIFRRY 492 + C G+ + LFV +R+ Sbjct: 423 RVCVGESLARIELFLFVSRPLQRF 446 >1UE8-A nrPDB Length = 367 Score = 35.8 bits (81), Expect = 0.053, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 378 VYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFV 437 V E LRF PPV K+ + I + GE++ + A RD ++F D F+ Sbjct: 244 VEEALRFSPPVMRTIRVTKEKVKIRDQ----VIDEGELVRVWIASANRDEEVFKDPDSFI 299 Query: 438 PER 440 P+R Sbjct: 300 PDR 302 >2PG7-A nrPDB Length = 476 Score = 35.4 bits (80), Expect = 0.055, Method: Compositional matrix adjust. Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 13/151 (8%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGR-AKKDLVI 401 +V ++ EEI VI N + KM ++V++E RF + R KKD Sbjct: 300 EVEAKVHEEIDRVIGKNR-QPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF 358 Query: 402 ESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPET 461 F + G +Y RDP F +F P+ F+ E+G+ + Sbjct: 359 RD----FFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQ-------FKKSDAF 407 Query: 462 ETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 ++G + C G+ + LF + + + Sbjct: 408 VPFSIGKRNCFGEGLARMELFLFFTTVMQNF 438 >6AYB-A nrPDB Length = 466 Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust. Identities = 44/211 (20%), Positives = 86/211 (40%), Gaps = 26/211 (12%) Query: 294 GEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIR 353 G+ L + ++GI ++ ++W M ++ + +V ++ +E Sbjct: 250 GQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVI----------SNKKVLEKVRKEQE 299 Query: 354 SVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAG 413 ++ S+ L + KM+ ++ + E LR PP+ A+K E + + G Sbjct: 300 EIMGSDKV-LDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQ----YIIPKG 354 Query: 414 EMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAG 473 +L +A R + D F PER + + ++ G G +C G Sbjct: 355 NILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVPFG-------AGRHKCIG 407 Query: 474 KDFVVLVARLFVIEIFRRYDSFDIE-VGTSP 503 ++F +L + +I I RY FD+E +G P Sbjct: 408 ENFALLQVK-SIISILLRY--FDMEYIGKIP 435 >5L94-A nrPDB Length = 410 Score = 35.4 bits (80), Expect = 0.063, Method: Compositional matrix adjust. Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 20/125 (16%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 EL S + E LR+ PV A + K+D+ + A K+KAGE + + A RD + F+ Sbjct: 273 ELLPSGIEEVLRYRSPVQALHRIVKEDVTL----AGKKLKAGEHVVPWMGSAHRDAEYFE 328 Query: 432 RADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 + F +R K H+ + G C G + A++ + E+ R Sbjct: 329 DPEVFKIDR-------KPNVHMAFGRGIHF---------CLGAPLARIEAKIMLAELIDR 372 Query: 492 YDSFD 496 Y D Sbjct: 373 YPQMD 377 >3TBG-A nrPDB Length = 479 Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust. Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 22/162 (13%) Query: 344 VHNRLAEEIRSVIKSNGGEL---TMGAIEKMELTKSVVYECLRFEPPVTAQYGR-AKKDL 399 V R+ +EI VI G++ MG M T +V++E RF V +D+ Sbjct: 305 VQRRVQQEIDDVI----GQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 360 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 ++ F++ G L +D ++++ F PE F+ +G + P Sbjct: 361 EVQ----GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV--------KP 408 Query: 460 ETETP-TVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVG 500 E P + G + C G+ + LF + + + SF + G Sbjct: 409 EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTG 449 >4RM4-A nrPDB Length = 396 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 4/65 (6%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 EL V E LRF P AK+D I H +K G+M+ + A RD FD Sbjct: 270 ELMPQAVEEALRFRAPAPVLRRIAKRDTEIGGH----LIKEGDMVLAFVASANRDEAKFD 325 Query: 432 RADEF 436 R F Sbjct: 326 RPHMF 330 >3S79-A nrPDB Length = 503 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 33/150 (22%), Positives = 70/150 (46%), Gaps = 18/150 (12%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 V + +EI++VI ++ + I+K+++ ++ +YE +R++P V +A +D VI+ Sbjct: 327 NVEEAIIKEIQTVIGER--DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVID 384 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 + VK G + R + F + +EF E F + + + GP Sbjct: 385 ----GYPVKKGTNIILNIGRMHR-LEFFPKPNEFTLENFAKNVPYRYFQP--FGFGP--- 434 Query: 463 TPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 + CAGK +++ + ++ + RR+ Sbjct: 435 ------RGCAGKYIAMVMMKAILVTLLRRF 458 >3BUJ-A nrPDB Length = 397 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 +L V ECLR++P V + + L ++ +++ +++ A RDP+ +D Sbjct: 264 DLLAQAVEECLRYDPSVQSN----TRQLDVDVELRGRRLRRDDVVVVLAGAANRDPRRYD 319 Query: 432 RADEFVPER 440 R D+F ER Sbjct: 320 RPDDFDIER 328 >5OFQ-A nrPDB Length = 409 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 + L ++V E LR+ PP+ A A +D+ + K+K G+ + + A RD F Sbjct: 271 ISLVPNLVEETLRYYPPIQAIGRIAAEDVEL----GECKIKRGQQVISWAASANRDSAKF 326 Query: 431 DRADEFVPER 440 + D FV R Sbjct: 327 EWPDTFVVHR 336 >1WIY-A nrPDB Length = 389 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 15/113 (13%) Query: 380 ECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPE 439 E LR PP R ++ L++ ++ G L P T+ F + F PE Sbjct: 260 EALRLYPPAWILTRRLERPLLLGED----RLPQGTTLV-LSPYVTQR-LYFPEGEAFQPE 313 Query: 440 RFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 RF+ E G R+ + +G + C G+DF +L + + FRR+ Sbjct: 314 RFLAERGTPSGRYFPFG---------LGQRLCLGRDFALLEGPIVLRAFFRRF 357 >1F4U-A nrPDB Length = 368 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 4/73 (5%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 I + L + E LR+ PPV + K+ + + ++ GE + + A RD Sbjct: 234 IREENLYLKAIEEALRYSPPVMRTVRKTKERVKLGDQ----TIEEGEYVRVWIASANRDE 289 Query: 428 KIFDRADEFVPER 440 ++F ++F+P+R Sbjct: 290 EVFHDGEKFIPDR 302 >1Q5D-A nrPDB Length = 419 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 21/121 (17%) Query: 373 LTKSVVYECLRFEPPVTAQYGR-AKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 L ++ + E LRF+ + R A++DL +K GEM++ P A RD +F Sbjct: 286 LMRNALDEVLRFDNILRIGTVRFARQDL----EYCGASIKKGEMVFLLIPSALRDGTVFS 341 Query: 432 RADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 R D F R + + GP C G L A + V IFRR Sbjct: 342 RPDVFDVRRDTSA-------SLAYGRGPHV---------CPGVSLARLEAEIAVGTIFRR 385 Query: 492 Y 492 + Sbjct: 386 F 386 >1CPT-A nrPDB Length = 428 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 29/149 (19%) Query: 369 EKMELTKS-------VVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQP 421 E++ L KS +V E +R+ PV + A D + + +K G+ + P Sbjct: 288 EQLALAKSDPALIPRLVDEAVRWTAPVKSFMRTALADTEVRGQN----IKRGDRIMLSYP 343 Query: 422 LATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVA 481 A RD ++F DEF RF RH+ + G C G+ L Sbjct: 344 SANRDEEVFSNPDEFDITRFPN-------RHLGFG---------WGAHMCLGQHLAKLEM 387 Query: 482 RLFVIEIFRRYDSFDIEVGTSPLGSSVNF 510 ++F E+ + S +E+ P + NF Sbjct: 388 KIFFEELLPKLKS--VELSGPPRLVATNF 414 >3K9V-A nrPDB Length = 482 Score = 32.7 bits (73), Expect = 0.41, Method: Compositional matrix adjust. Identities = 33/152 (21%), Positives = 59/152 (38%), Gaps = 15/152 (9%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 Q RL +E++SV+ N + M K+ + E +R P V K V+ Sbjct: 315 QAQRRLLQEVQSVLPDNQTP-RAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVL- 372 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 + + G +L + F+ + +F PER++ +E + P Sbjct: 373 ---GEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKKI---------NPFAH 420 Query: 463 TP-TVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 P +G + C G+ L L + I ++YD Sbjct: 421 LPFGIGKRMCIGRRLAELQLHLALCWIIQKYD 452 >6H03-D nrPDB Length = 821 Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 86/232 (37%), Gaps = 36/232 (15%) Query: 106 FIAENPQVVALLDG-----KSFPVLFDVDKVEKK-DLFTGTYMPSTELTGGYRILSYLDP 159 FI NP+ + L + P L+D + D + Y+ S L G YR+L Y+D Sbjct: 240 FINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDS 299 Query: 160 SEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELS------LKGKADFGGSS 213 + K ++ KSS +F + + ++ K S L+G+ G Sbjct: 300 EKLKQNDFNSVEEKKCKSSGWHFVVKFSSHGCKELENALKAASGTQNNVLRGEPFIRGGG 359 Query: 214 DG--TAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTF 271 G + ++L NPA K + A W LP+VI++ L + Sbjct: 360 AGFISGLSYLEL----DNPAGNKRRYSA------WAES------VTNLPQVIKQKLTPLY 403 Query: 272 SL----PPALVKSDYQR--LYEFFLESAGEILVEADKLGISREEATHNLLFA 317 L P A VK Y + L E+ E G++ E TH L Sbjct: 404 ELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHC 455 >4WMZ-A nrPDB Length = 539 Score = 32.0 bits (71), Expect = 0.66, Method: Compositional matrix adjust. Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 17/114 (14%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V L EE V+ ELT +++M L + E LR P+ + + + KD+ + Sbjct: 336 VQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVP- 394 Query: 404 HDAAFKVKAGEMLY---GYQPLATRDPKIFDRADEFVPERF---------VGEE 445 + ++ + AG + GY L RD + F A +F R+ VGEE Sbjct: 395 -NTSYVIPAGYHVLVSPGYTHL--RD-EYFPNAHQFNIHRWNNDSASSYSVGEE 444 >5H1Z-A nrPDB Length = 407 Score = 32.0 bits (71), Expect = 0.67, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 4/68 (5%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 + + V E +R++ P+ A D +E ++KAG+ L + A RD +F+ Sbjct: 277 MIPNTVQEIIRWQTPLAHMRRTATVDSELEGQ----QIKAGDKLALWYISANRDESVFEN 332 Query: 433 ADEFVPER 440 AD + +R Sbjct: 333 ADRIIVDR 340 >6F0B-A nrPDB Length = 395 Score = 32.0 bits (71), Expect = 0.72, Method: Compositional matrix adjust. Identities = 32/124 (25%), Positives = 49/124 (39%), Gaps = 21/124 (16%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGR-AKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 E E +V E LR+ GR A +D+ + V+AG+M+ PLA RD Sbjct: 261 EHPERIPLLVEELLRYHTVSQLGLGRIATEDVEV----GGVTVRAGQMVVAALPLANRDE 316 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 +F DE +R + HV + GP QC G+ + + + Sbjct: 317 SVFPNPDELDFDR-------PSVPHVGFGYGP---------HQCVGQALARVELQEAIPA 360 Query: 488 IFRR 491 + RR Sbjct: 361 VIRR 364 >2X2N-A nrPDB Length = 475 Score = 32.0 bits (71), Expect = 0.73, Method: Compositional matrix adjust. Identities = 36/174 (20%), Positives = 65/174 (37%), Gaps = 30/174 (17%) Query: 321 NTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMG-AIEKMELTKSVVY 379 TW + ++ P VK + E +R I+ +L +++M + Sbjct: 286 TTWSMLHLMHPANVKHL------------EALRKEIEEFPAQLNYNNVMDEMPFAERCAR 333 Query: 380 ECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPE 439 E +R +PP+ + D+ + S + V G+++ L+ D + F + PE Sbjct: 334 ESIRRDPPLLMLMRKVMADVKVGS----YVVPKGDIIACSPLLSHHDEEAFPEPRRWDPE 389 Query: 440 RFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 R EG G G +C G+ F +L + + FR YD Sbjct: 390 RDEKVEG------AFIGFG-------AGVHKCIGQKFGLLQVKTILATAFRSYD 430 >6HQW-A nrPDB Length = 445 Score = 31.6 bits (70), Expect = 0.79, Method: Compositional matrix adjust. Identities = 27/119 (22%), Positives = 49/119 (41%), Gaps = 19/119 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L + V EC+R+ P+ A D + + ++KAGE + + A RD +F+ Sbjct: 315 LIPNAVQECIRYVTPLAHMRRTATADTELFGN----QIKAGEKVILWYISANRDETVFEN 370 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 D+ + +R RH+ + + G +C G L R+ + E+ R Sbjct: 371 PDKLMVDR------PNARRHLSFGH---------GIHRCVGARLAELQLRILLEEMHER 414 >5E0E-A nrPDB Length = 463 Score = 31.6 bits (70), Expect = 0.90, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEP--PVTAQYGRAKKDLV 400 V ++ +EI VI S+ T+ KM T++V+YE RF P+ + K L Sbjct: 291 HVAEKVQKEIDQVIGSHRLP-TLEDRTKMPYTEAVIYEIQRFSDLIPIGVPHKVTKDTLF 349 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEG 446 + + +Y A DP+ F++ D F P+ F+ G Sbjct: 350 -----RGYLLPKNTEVYPILSSALHDPQYFEQPDTFNPDHFLDANG 390 >1WR8-A nrPDB Length = 231 Score = 31.6 bits (70), Expect = 0.92, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 12/75 (16%) Query: 380 ECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPE 439 E L +P A G + DL AFKV GY+ + PKI ++V + Sbjct: 163 EFLGIKPKEVAHVGDGENDL------DAFKV------VGYKVAVAQAPKILKENADYVTK 210 Query: 440 RFVGEEGEKLLRHVL 454 + GE G + + H+L Sbjct: 211 KEYGEGGAEAIYHIL 225 >4XE3-A nrPDB Length = 407 Score = 31.6 bits (70), Expect = 0.97, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 20/167 (11%) Query: 277 LVKSDYQRLYEFFLESAGEILVEADKLGISREEA-THNLLFATCFNTWGGMKIL---FPN 332 L ++ QR+ + F+ V D L R +A T +LL A T + N Sbjct: 184 LTAAEIQRVQQDFM-------VYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVN 236 Query: 333 MVKRIGRAGHQVH-NRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTA- 390 M + AGH+ N++ + ++ ++ + L + V E LR+ P V+A Sbjct: 237 MGVSLLIAGHETSVNQITNLVHLLLTERKRYESL--VADPALVPAAVEEMLRYTPLVSAG 294 Query: 391 QYGR-AKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEF 436 + R A +D+ + + V+AGE + A RD ++FD ADE Sbjct: 295 SFVRVATEDVELST----VTVRAGEPCVVHFASANRDEEVFDHADEL 337 >3P3Z-A nrPDB Length = 416 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 365 MGAIEKMELTKSVVYECLRFEP--PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPL 422 M E EL V E LR+ P PVTA A +D + ++ G ++ + Sbjct: 277 MKIKENPELAPQAVEEVLRWSPTLPVTATR-VAAEDFEVN----GVRIPTGTPVFMCAHV 331 Query: 423 ATRDPKIFDRADEF 436 A RDP++F AD F Sbjct: 332 AHRDPRVFADADRF 345 >6C94-A nrPDB Length = 497 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 15/138 (10%) Query: 342 HQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVI 401 HQ R EE+R ++ + + KM + EC R PPV Y + K + Sbjct: 315 HQ--QRCREEVREIL-GDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPV-- 369 Query: 402 ESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPET 461 S + AG ++ + R+ ++ + F P RF E RH P Sbjct: 370 -SFVDGRSLPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSPENSSG--RH------PYA 420 Query: 462 ETP-TVGNKQCAGKDFVV 478 P + G + C G+ F + Sbjct: 421 FIPFSAGPRNCIGQQFAM 438 >5VDN-A nrPDB Length = 463 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 253 PLLSIGLPRVI--EEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEA 310 PL+ L V+ E P +HT S+P A++K+ L LE+ E+ V+ I RE A Sbjct: 221 PLIVETLLEVMNTEGPKLHTESVPKAVIKNADGSL-TLQLENGTEVTVDHLIWAIGREPA 279 Query: 311 THNL 314 T NL Sbjct: 280 TDNL 283 >3RWL-A nrPDB Length = 426 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 28/138 (20%), Positives = 57/138 (41%), Gaps = 21/138 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L +++V E +R++ P+ ++ + +S ++ G+ + + RD ++ DR Sbjct: 297 LVETMVPEIIRWQTPL----AHMRRTAIADSELGGKTIRKGDKVVMWYYSGNRDDEVIDR 352 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 +EF+ +R + +H+ + G +C G + R+ EI R+ Sbjct: 353 PEEFIIDR------PRPRQHLSFG---------FGIHRCVGNRLAEMQLRILWEEILTRF 397 Query: 493 DSFDIEVGTSPLGSSVNF 510 IEV P NF Sbjct: 398 SR--IEVMAEPERVRSNF 413 >5M0P-A nrPDB Length = 428 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 20/106 (18%) Query: 380 ECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPE 439 E R+ P V G+AK D+ + V +YG T D ++D +EF PE Sbjct: 290 EVRRYYPFVPFLPGKAKVDIDFQGVTIPAGVGLALDVYG----TTHDESLWDDPNEFRPE 345 Query: 440 RFVGEEGEKLLRHVLWSNGPETETPTVG-----NKQCAGKDFVVLV 480 RF W P P G N +CAG+ V++ Sbjct: 346 RF-----------ETWDGSPFDLIPQGGGDYWTNHRCAGEWITVII 380 >3NC3-A nrPDB Length = 441 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Query: 359 NGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 N E + L + E LR++PPV + +D V+ ++K +++ Sbjct: 287 NNPEQMNDVLADRSLVPRAIAETLRYKPPVQLIPRQLSQDTVV----GGMEIKKDTIVFC 342 Query: 419 YQPLATRDPKIFDRADEFVPER 440 A RDP+ F++ D F R Sbjct: 343 MIGAANRDPEAFEQPDVFNIHR 364 >6DWN-A nrPDB Length = 491 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 15/109 (13%) Query: 407 AFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEG--EKLLRHVLWSNGPETETP 464 F + G ++ Q D K++ EF+PERF+ +G +K+L + G Sbjct: 371 GFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFG------ 424 Query: 465 TVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSL 513 +G ++C G+ LF+ + +R + F + PLG V+ + + Sbjct: 425 -MGKRKCIGETIARWEVFLFLAILLQRVE-FSV-----PLGVKVDMTPI 466 >6M7X-A nrPDB Length = 484 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 14/109 (12%) Query: 367 AIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRD 426 A ++ L ++ + E LR P A DLV+++ + + AG ++ + R+ Sbjct: 335 ATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN----YHIPAGTLVRVFLYSLGRN 390 Query: 427 PKIFDRADEFVPERFVGEEGE-KLLRHVLWSNGPETETPTVGNKQCAGK 474 P +F R + + P+R++ G + HV + G +QC G+ Sbjct: 391 PALFPRPERYNPQRWLDIRGSGRNFYHVPFG---------FGMRQCLGR 430 >6G5O-A nrPDB Length = 399 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 4/72 (5%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 E+T V E +R+ P+T Q GR + ++H VKA + A RD +F+ Sbjct: 251 EITGRAVEEMIRYFSPLT-QMGRVVTE---DTHVCEHAVKADSRISLCWASANRDAAVFE 306 Query: 432 RADEFVPERFVG 443 +E V +R V Sbjct: 307 NPNEIVLDRKVN 318 >3A1L-A nrPDB Length = 425 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 E T + V E +R++PPV A A +D+ + HD + G + A RDP F Sbjct: 285 ESTPAAVEELMRYDPPVQAVTRWAYEDIRLGDHD----IPRGSRVVALLGSANRDPARF 339 >4YZR-A nrPDB Length = 405 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Query: 372 ELTKSVVYECLRFEPPVTAQYGR-AKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 E+ + V E LR+ PV R A +D + H +K G+M++ A RDP F Sbjct: 272 EMIATAVEELLRYTSPVVMMANRWAIEDFTYKGH----SIKRGDMIFIGIGSANRDPNFF 327 Query: 431 D 431 + Sbjct: 328 E 328 >3L4D-A nrPDB Length = 453 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 27/126 (21%), Positives = 52/126 (41%), Gaps = 16/126 (12%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 +E+M + E +R +PP+ + K + + + V G+++ L+ +D Sbjct: 308 MEEMPFAEQCARESIRRDPPLVMLMRKVLKPVQV----GKYVVPEGDIIACSPLLSHQDE 363 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 + F E+ PER + KL+ G G +C G+ F +L + + Sbjct: 364 EAFPNPREWNPERNM-----KLVDGAFCGFG-------AGVHKCIGEKFGLLQVKTVLAT 411 Query: 488 IFRRYD 493 + R YD Sbjct: 412 VLRDYD 417 >3TKT-A nrPDB Length = 450 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 20/125 (16%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L +V E +R+ PV A D + K+ AG+ L A DP F Sbjct: 321 LLPGIVEEAIRWTTPVQHFMRTAATDTELCGQ----KIAAGDWLMLNYVAANHDPAQFPE 376 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 +F P R RH+ + G+ QC G L R+ + + R Sbjct: 377 PRKFDPTRPAN-------RHLAFG---------AGSHQCLGLHLARLEMRVLLDVLLDRV 420 Query: 493 DSFDI 497 DS ++ Sbjct: 421 DSLEL 425 >2ZQJ-A nrPDB Length = 417 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 4/30 (13%) Query: 416 LYGYQPLATRDPKIFDRADEFVPERFVGEE 445 LYG DP+++D DEF PERF E Sbjct: 318 LYG----TNHDPRLWDHPDEFRPERFAERE 343 >5D2Y-A nrPDB Length = 264 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 32/154 (20%), Positives = 65/154 (42%), Gaps = 18/154 (11%) Query: 291 ESAGEILVE-ADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRI----------GR 339 E+A E+++ ADK+ I+ + L T+G ++ KR+ G+ Sbjct: 88 ETASELILRGADKVEINTAAVENPSLITQIAQTFGSQAVVVYIAAKRVDGEFMVFTYSGK 147 Query: 340 AGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVT-----AQYGR 394 + L + + V K GE+ +G+I+++ E +RF P+T A G Sbjct: 148 KNTGI--LLRDWVVEVEKRGAGEIVLGSIDRLGTKSGYDTEMIRFVRPLTTLPIIAHRGA 205 Query: 395 AKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 K + +E+ A + ++ ++ + R+ K Sbjct: 206 GKMEHFLEAFLAGADAAKADSVFHFREIDVRELK 239 >6NT6-A nrPDB Length = 392 Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/37 (32%), Positives = 22/37 (59%) Query: 144 STELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRN 180 S E G YR+++Y +P+EP+ L L+ + L+ + Sbjct: 307 SKECAGLYRLIAYEEPAEPESHFLSGLILWHLQQQQR 343 >1WKR-A nrPDB Length = 340 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 357 KSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYG 393 S GELT GA + + T S+ Y + P +A +G Sbjct: 154 SSTNGELTFGATDSSKYTGSITYTPITSTSPASAYWG 190 >5KB6-A nrPDB Length = 363 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 3/47 (6%) Query: 230 PADTKLKADAPGLITKWVLFNL-HPLLSIGLPRVIEEPLIHTFSLPP 275 P KLK +AP +++ VLF + +PLL I V+++ + +SL P Sbjct: 9 PKPKKLKVEAPQALSENVLFGMGNPLLDISA--VVDKDFLDKYSLKP 53 >3EB7-A nrPDB Length = 589 Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 34/154 (22%) Query: 54 IRNIPGNYGLPIVGPI---------------KDRWDYFYDQGAEEFFKSRIRKYNSTVYR 98 + I G G+P+VGPI K +W+ F +Q E +I +Y Sbjct: 14 VGTILGKLGVPLVGPIVSLYSTLIDVLWPGGKSQWEIFMEQ-VEALINQKIAEYARAKAL 72 Query: 99 VNMPPGAFIAENPQ--VVALLDGKSFP----VLFDV-DKVEKKDLFTGTYMPSTELTGGY 151 + + N Q + AL + + P VL DV ++ E D YMPS + Sbjct: 73 AELEG---LGNNYQLYLTALEEWQENPSSTRVLRDVRNRFEILDSLFTQYMPS------F 123 Query: 152 RILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPE 185 R+ Y P + + NL LLK + IF E Sbjct: 124 RVTGYEVPLLSVYAQAANLHLLLLKDA--SIFGE 155 >5HDI-A nrPDB Length = 404 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 EL + + E LR+EPP Y + ++ + + A L A RDP F+ Sbjct: 275 ELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTE----LPADSHLLLLWGAANRDPAQFE 330 Query: 432 RADEFVPERFVGE 444 EF +R G+ Sbjct: 331 APGEFRLDRAGGK 343 >4Q98-A nrPDB Length = 369 Score = 28.9 bits (63), Expect = 6.3, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 363 LTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGY 419 L + A ELT + E +TA+ AK +L++ AAF +K G YGY Sbjct: 78 LVVVANHNYELTGKSLNEVEALTTSLTAENQNAK-NLIMTGKSAAFTIKPGSNHYGY 133 >5YLW-A nrPDB Length = 495 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%) Query: 347 RLAEEIRSVIKSNGGE--LTMGAIEKMELTKSVVYECLRFEPPVTAQYGR-AKKDLVIES 403 RL E++SV G E + A+ K+ ++V+ E +R PP R A+ D + Sbjct: 323 RLKAELKSVA---GDEKIVDESAMPKLPYLQAVIKEVMRIHPPGPLLLPRKAESDQEVN- 378 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFV 442 + + G + RDP I+ + F PERF+ Sbjct: 379 ---GYLIPKGTQILINAYAIGRDPSIWTDPETFDPERFL 414 >4B9P-A nrPDB Length = 166 Score = 28.1 bits (61), Expect = 9.1, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 54 IRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKS 87 I I +Y L + P W+Y YDQ ++ F + Sbjct: 108 ISRIGNSYALSLATPPYSEWNYMYDQNSDYSFNN 141 >3IBD-A nrPDB Length = 476 Score = 28.1 bits (61), Expect = 9.2, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 20/112 (17%) Query: 343 QVHNRLAEEIRSVIKSNGG-ELTMGAIEKMELTKSVVYECLRFE-------PPVTAQYGR 394 V R+ EI VI + EL A KM T++V+YE RF P + Q+ Sbjct: 300 HVAERVYREIEQVIGPHRPPELHDRA--KMPYTEAVIYEIQRFSDLLPMGVPHIVTQHT- 356 Query: 395 AKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEG 446 + + +I F + + A DP F++ D F P+ F+ G Sbjct: 357 SFRGYIIPKDTEVFLILST---------ALHDPHYFEKPDAFNPDHFLDANG 399 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2RCM-A nrPDB 864 0.0 3DBM-A nrPDB 739 0.0 6DA2-A nrPDB 160 1e-39 5VEU-A nrPDB 156 2e-38 2W0A-A nrPDB 150 1e-36 3EL3-A nrPDB 150 1e-36 2VE3-A nrPDB 141 7e-34 3MZS-A nrPDB 141 9e-34 5FYF-A nrPDB 134 1e-31 Sequences not found previously or not previously below threshold: 3N9Z-A nrPDB 113 2e-25 3RWL-A nrPDB 104 1e-22 4R20-A nrPDB 100 2e-21 6AYB-A nrPDB 97 2e-20 6HQG-A nrPDB 96 5e-20 6C94-A nrPDB 95 7e-20 3K9V-A nrPDB 94 1e-19 3DL9-A nrPDB 92 6e-19 3JUS-A nrPDB 91 1e-18 5YLW-A nrPDB 91 1e-18 2WX2-A nrPDB 90 2e-18 6HQD-A nrPDB 89 6e-18 3TKT-A nrPDB 88 1e-17 4WMZ-A nrPDB 87 2e-17 6M7X-A nrPDB 86 3e-17 1CPT-A nrPDB 86 4e-17 5FSA-A nrPDB 86 4e-17 4R1Z-A nrPDB 86 4e-17 6B82-A nrPDB 86 4e-17 3MDV-A nrPDB 85 8e-17 2X2N-A nrPDB 84 2e-16 5JLC-A nrPDB 84 2e-16 2PG7-A nrPDB 84 2e-16 3SN5-A nrPDB 83 2e-16 3QZ1-A nrPDB 83 2e-16 5H1Z-A nrPDB 83 3e-16 6CR2-A nrPDB 83 4e-16 3E6I-A nrPDB 82 5e-16 4KPA-A nrPDB 82 5e-16 4ZGX-A nrPDB 82 8e-16 3S79-A nrPDB 81 1e-15 1N6B-A nrPDB 81 1e-15 5VBU-A nrPDB 81 1e-15 6HQW-A nrPDB 81 1e-15 5LIE-A nrPDB 81 1e-15 3L4D-A nrPDB 80 2e-15 5UYS-A nrPDB 80 2e-15 3TBG-A nrPDB 80 2e-15 6IQ5-A nrPDB 80 3e-15 5W0C-A nrPDB 80 3e-15 4H1N-A nrPDB 79 3e-15 5E0E-A nrPDB 79 5e-15 4RM4-A nrPDB 79 6e-15 4GQS-A nrPDB 78 7e-15 6DWN-A nrPDB 78 8e-15 2NNH-A nrPDB 78 9e-15 5E58-A nrPDB 78 1e-14 3IBD-A nrPDB 77 2e-14 2HI4-A nrPDB 77 3e-14 3MGX-A nrPDB 74 1e-13 2WIO-A nrPDB 72 6e-13 5L94-A nrPDB 72 7e-13 1UE8-A nrPDB 72 8e-13 6GII-A nrPDB 70 2e-12 1F4U-A nrPDB 69 3e-12 5OFQ-A nrPDB 69 4e-12 2WIY-A nrPDB 67 1e-11 5DE9-A nrPDB 67 2e-11 6B11-A nrPDB 67 2e-11 5M0P-A nrPDB 67 2e-11 3NC3-A nrPDB 67 2e-11 4OQR-A nrPDB 66 4e-11 3R9C-A nrPDB 66 4e-11 2IAG-A nrPDB 66 4e-11 1WIY-A nrPDB 65 6e-11 3P3Z-A nrPDB 65 7e-11 4PWV-A nrPDB 65 8e-11 4Z5P-A nrPDB 65 8e-11 4OQS-A nrPDB 65 8e-11 5FOI-A nrPDB 65 8e-11 3AWQ-A nrPDB 65 9e-11 3EJB-B nrPDB 64 1e-10 4GGV-A nrPDB 64 1e-10 6F0B-A nrPDB 64 2e-10 5XJN-A nrPDB 63 3e-10 5GWE-A nrPDB 63 3e-10 4YZR-A nrPDB 63 3e-10 5DQN-A nrPDB 63 3e-10 5IT1-A nrPDB 63 4e-10 2FR7-A nrPDB 63 4e-10 1EHE-A nrPDB 62 4e-10 3B98-A nrPDB 62 6e-10 5VWS-A nrPDB 62 6e-10 4TRI-A nrPDB 62 7e-10 6GMF-A nrPDB 62 8e-10 3A1L-A nrPDB 61 9e-10 6FYJ-A nrPDB 61 1e-09 2UUQ-A nrPDB 60 2e-09 6BLD-A nrPDB 60 2e-09 3ABB-A nrPDB 60 2e-09 5XW2-A nrPDB 60 2e-09 6DCD-A nrPDB 60 2e-09 1Z8P-A nrPDB 60 2e-09 3TYW-A nrPDB 60 2e-09 2XKR-A nrPDB 60 3e-09 2ZQJ-A nrPDB 60 3e-09 4DO1-A nrPDB 60 3e-09 3ABA-A nrPDB 59 4e-09 2Y5N-A nrPDB 59 4e-09 1LG9-A nrPDB 59 6e-09 2Z36-A nrPDB 59 6e-09 2NZA-A nrPDB 59 6e-09 1ODO-A nrPDB 59 6e-09 4YT3-A nrPDB 59 7e-09 4FB2-A nrPDB 58 8e-09 5LIV-A nrPDB 58 1e-08 2RFC-A nrPDB 58 1e-08 5D3U-A nrPDB 57 1e-08 5HIW-A nrPDB 57 1e-08 4MM0-A nrPDB 57 2e-08 5HDI-A nrPDB 57 2e-08 6F88-A nrPDB 57 2e-08 6GK6-A nrPDB 57 2e-08 5EX6-C nrPDB 57 2e-08 3BUJ-A nrPDB 57 3e-08 5YHJ-A nrPDB 56 3e-08 5Y1I-A nrPDB 56 3e-08 5Z9I-A nrPDB 56 4e-08 6A7I-A nrPDB 56 4e-08 5CJE-A nrPDB 56 4e-08 1UED-A nrPDB 56 4e-08 1GWI-A nrPDB 56 5e-08 1Q5D-A nrPDB 55 5e-08 2VZM-A nrPDB 55 6e-08 3OFT-A nrPDB 55 1e-07 4XE3-A nrPDB 55 1e-07 5NWS-A nrPDB 54 2e-07 6G5O-A nrPDB 54 2e-07 4WPZ-A nrPDB 54 2e-07 4JBT-A nrPDB 53 2e-07 5YSW-A nrPDB 53 3e-07 5XNT-A nrPDB 53 3e-07 5OMS-A nrPDB 53 3e-07 6A7J-A nrPDB 53 3e-07 2ZBZ-A nrPDB 53 4e-07 5KYO-A nrPDB 52 5e-07 3NV6-A nrPDB 52 8e-07 6FSH-A nrPDB 51 1e-06 4TX3-A nrPDB 51 1e-06 6G71-A nrPDB 49 4e-06 3WEC-A nrPDB 49 5e-06 5L1U-A nrPDB 49 6e-06 4UBS-A nrPDB 49 7e-06 3A50-A nrPDB 49 8e-06 3WVS-A nrPDB 48 8e-06 4Z5Q-A nrPDB 48 1e-05 4C9K-A nrPDB 47 3e-05 2YJN-B nrPDB 44 1e-04 2IJ7-A nrPDB 42 6e-04 6AUN-A nrPDB 37 0.021 6H03-D nrPDB 35 0.053 3EB7-A nrPDB 34 0.12 4BPT-A nrPDB 33 0.26 2NYA-A nrPDB 33 0.33 4W8Z-A nrPDB 32 0.44 5KB6-A nrPDB 32 0.60 1Z7A-A nrPDB 32 0.63 3CQL-A nrPDB 32 0.65 3AF5-A nrPDB 31 1.2 3ICS-A nrPDB 31 1.5 5JOV-A nrPDB 30 2.0 6NT6-A nrPDB 30 2.3 5ZCR-A nrPDB 30 2.5 3BU7-A nrPDB 30 2.9 5VDN-A nrPDB 30 3.2 5D2Y-A nrPDB 30 3.6 2RHI-A nrPDB 28 9.1 4M8Z-A nrPDB 28 9.6 >2RCM-A nrPDB Length = 495 Score = 864 bits (2233), Expect = 0.0, Method: Composition-based stats. Identities = 484/486 (99%), Positives = 485/486 (99%) Query: 33 ASGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKY 92 +SGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKY Sbjct: 6 SSGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKY 65 Query: 93 NSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDLFTGTYMPSTELTGGYR 152 NSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDL TGTYMPSTELTGGYR Sbjct: 66 NSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDLLTGTYMPSTELTGGYR 125 Query: 153 ILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGS 212 ILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGS Sbjct: 126 ILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGS 185 Query: 213 SDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFS 272 SDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFS Sbjct: 186 SDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFS 245 Query: 273 LPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPN 332 LPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPN Sbjct: 246 LPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPN 305 Query: 333 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY 392 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY Sbjct: 306 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY 365 Query: 393 GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRH 452 GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRH Sbjct: 366 GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRH 425 Query: 453 VLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS 512 VLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS Sbjct: 426 VLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS 485 Query: 513 LRKASF 518 LRKASF Sbjct: 486 LRKASF 491 >3DBM-A nrPDB Length = 473 Score = 739 bits (1909), Expect = 0.0, Method: Composition-based stats. Identities = 296/467 (63%), Positives = 375/467 (80%), Gaps = 3/467 (0%) Query: 53 PIRNIPGNYGLPIVGPIKDRWDYFYDQGA-EEFFKSRIRKYNSTVYRVNMPPGAFIAENP 111 P+R IPG+YG+P PIKDR +YFY G +E+F+SR++KY STV+R NMPPG F++ NP Sbjct: 7 PLREIPGSYGIPFFQPIKDRLEYFYGTGGRDEYFRSRMQKYQSTVFRANMPPGPFVSSNP 66 Query: 112 QVVALLDGKSFPVLFDVDKVEKKDLFTGTYMPSTELTGGYRILSYLDPSEPKHEKLKNLL 171 +V+ LLD KSFP+LFDV KVEKKDLFTGTYMPST+LTGGYR+LSYLDPSEP+H +LKNLL Sbjct: 67 KVIVLLDAKSFPILFDVSKVEKKDLFTGTYMPSTKLTGGYRVLSYLDPSEPRHAQLKNLL 126 Query: 172 FFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGSSDGTAFNFLARAFYGTNPA 231 FF+LK+S NR+ P+F+ TY+ELF+ LE EL+ GKA F + AF FL RA++ +NP Sbjct: 127 FFMLKNSSNRVIPQFETTYTELFEGLEAELAKNGKAAFNDVGEQAAFRFLGRAYFNSNPE 186 Query: 232 DTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLE 291 +TKL AP LI+ WVLFNL P L +GLP ++EPL+HTF LP L+KS Y +LY++F Sbjct: 187 ETKLGTSAPTLISSWVLFNLAPTLDLGLPWFLQEPLLHTFRLPAFLIKSTYNKLYDYFQS 246 Query: 292 SAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEE 351 A ++ +A+KLG+ ++EA HN+LFA CFNT+GG+KILFPN +K IG AG +H +LAEE Sbjct: 247 VATPVMEQAEKLGVPKDEAVHNILFAVCFNTFGGVKILFPNTLKWIGLAGENLHTQLAEE 306 Query: 352 IRSVIKSNG-GELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKV 410 IR IKS G G +T+ AIE+M LTKSVVYE LR EPPV QYG+AK + IESHDA F+V Sbjct: 307 IRGAIKSYGDGNVTLEAIEQMPLTKSVVYESLRIEPPVPPQYGKAKSNFTIESHDATFEV 366 Query: 411 KAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQ 470 K GEML+GYQP AT+DPK+FDR +E+VP+RFVG +GE LL++V WSNGPETE+PTV NKQ Sbjct: 367 KKGEMLFGYQPFATKDPKVFDRPEEYVPDRFVG-DGEALLKYVWWSNGPETESPTVENKQ 425 Query: 471 CAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSLRKAS 517 CAGKDFVVL+ RLFVIE+FRRYDSF+IE+G SPLG++V + L++AS Sbjct: 426 CAGKDFVVLITRLFVIELFRRYDSFEIELGESPLGAAVTLTFLKRAS 472 >6DA2-A nrPDB Length = 487 Score = 160 bits (405), Expect = 1e-39, Method: Composition-based stats. Identities = 44/171 (25%), Positives = 69/171 (40%), Gaps = 15/171 (8%) Query: 339 RAGHQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKK 397 A H V +L EEI +V+ N T + +ME VV E LR P KK Sbjct: 301 LATHPDVQQKLQEEIDAVL-PNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKK 359 Query: 398 DLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSN 457 D+ I + G ++ RDPK + ++F+PERF + + + Sbjct: 360 DVEINGMF----IPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNI-------- 407 Query: 458 GPETETP-TVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSS 507 P TP G + C G F ++ +L +I + + + + PL S Sbjct: 408 DPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 458 >5VEU-A nrPDB Length = 480 Score = 156 bits (394), Expect = 2e-38, Method: Composition-based stats. Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 16/156 (10%) Query: 339 RAGHQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKK 397 A H V +L +EI +V+ N T A+ +ME VV E LR P KK Sbjct: 300 LATHPDVQQKLQKEIDAVL-PNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKK 358 Query: 398 DLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSN 457 D+ I + G M+ DPK + +EF PERF ++ S Sbjct: 359 DVEINGVF----IPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD---------SI 405 Query: 458 GPETETP-TVGNKQCAGKDFVVLVARLFVIEIFRRY 492 P TP G + C G F ++ +L +I + + + Sbjct: 406 DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 441 >2W0A-A nrPDB Length = 455 Score = 150 bits (379), Expect = 1e-36, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 13/155 (8%) Query: 359 NGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 +G ++ A+ ++ ++V+ E LR PP+ AK + ++ H ++ G+++ Sbjct: 292 DGRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGH----RIHEGDLVAA 347 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVV 478 ++ R P+ F +FVP R+ E LL W G +C G F + Sbjct: 348 SPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWI------PFGAGRHRCVGAAFAI 401 Query: 479 LVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSL 513 + + + R Y+ E+ P + S + Sbjct: 402 MQIKAIFSVLLREYE---FEMAQPPESYRNDHSKM 433 >3EL3-A nrPDB Length = 467 Score = 150 bits (379), Expect = 1e-36, Method: Composition-based stats. Identities = 45/221 (20%), Positives = 86/221 (38%), Gaps = 21/221 (9%) Query: 294 GEILVEADKLGIS-REEATHNLLFATCFNTWGGMKILFPNMVKRI--GRAGHQVH-NRLA 349 +L D G E+ H+ + A T G I + + + A H H +R+ Sbjct: 246 TALLEAKDDNGDPIGEQEIHDQVVAIL--TPGSETI--ASTIMWLLQALADHPEHADRIR 301 Query: 350 EEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFK 409 +E+ +V + G + + K+ T +V+ E +R P V RA V ES ++ Sbjct: 302 DEVEAV--TGGRPVAFEDVRKLRHTGNVIVEAMRLRPAVWVLTRRA----VAESELGGYR 355 Query: 410 VKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNK 469 + AG + RDPK +D EF P+R++ E + ++ + + + G + Sbjct: 356 IPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAANVPKYAM-------KPFSAGKR 408 Query: 470 QCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNF 510 +C F + L + +Y + + + Sbjct: 409 KCPSDHFSMAQLTLITAALATKYRFEQVAGSNDAVRVGITL 449 >2VE3-A nrPDB Length = 444 Score = 141 bits (355), Expect = 7e-34, Method: Composition-based stats. Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 21/167 (12%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 + R+ +E + S ELT ++KM V+ E LR PPV G ++L+ + Sbjct: 276 IRERVRQEQNKLQLSQ--ELTAETLKKMPYLDQVLQEVLRLIPPV----GGGFRELIQDC 329 Query: 404 HDAAFKVKAGEMLYGYQPLATR-DPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 F G L YQ T DP ++ ++F PERF + N P Sbjct: 330 QFQGFHFPKG-WLVSYQISQTHADPDLYPDPEKFDPERFTPDGSAT-------HNPPFAH 381 Query: 463 TPTVGN-KQCAGKDFVVLVARLFVIEIFRRYD-----SFDIEVGTSP 503 P G ++C GK+F L +LF + +++D ++E+ +P Sbjct: 382 VPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTP 428 >3MZS-A nrPDB Length = 486 Score = 141 bits (355), Expect = 9e-34, Method: Composition-based stats. Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 16/157 (10%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 V L EE+ + + G+++ ++ + L K+ + E LR P + DLV++ Sbjct: 308 NVQEMLREEVLNARRQAEGDIS-KMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQ 366 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 + K +Y RDP F D+F P R++ ++ + + L Sbjct: 367 DYLIPAKTLVQVAIYA----MGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLG------- 415 Query: 463 TPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEV 499 G +QC G+ L LF+I I ++F +E+ Sbjct: 416 -FGWGVRQCVGRRIAELEMTLFLIHIL---ENFKVEM 448 >5FYF-A nrPDB Length = 470 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 22/158 (13%) Query: 354 SVIKSNGGELTMGAIE-KMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKA 412 ++ N ++ K EL ++V E +R++ P+ AK+D+ + +K Sbjct: 319 GLVAMNEFPREFEKLKAKPELIPNMVSEIIRWQTPLAYMRRIAKQDVELGGQ----TIKK 374 Query: 413 GEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCA 472 G+ + + RD + FD D+F+ +R + H+ + G +C Sbjct: 375 GDRVVMWYASGNRDERKFDNPDQFIIDR------KDARNHMSF---------GYGVHRCM 419 Query: 473 GKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNF 510 G L R+ EI +R+D +IEV P NF Sbjct: 420 GNRLAELQLRILWEEILKRFD--NIEVVEEPERVQSNF 455 >3N9Z-A nrPDB Length = 487 Score = 113 bits (283), Expect = 2e-25, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 60/157 (38%), Gaps = 16/157 (10%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 +V + L E+ + G++ ++ + L K+ + E LR P DLV+ Sbjct: 307 KVQDMLRAEVLAARHQAQGDMAT-MLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLR 365 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 + K +Y R+P F + F P R++ ++ L Sbjct: 366 DYMIPAKTLVQVAIYA----LGREPTFFFDPENFDPTRWLSKDKNITYFRNLG------- 414 Query: 463 TPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEV 499 G +QC G+ L +F+I + ++F +E+ Sbjct: 415 -FGWGVRQCLGRRIAELEMTIFLINML---ENFRVEI 447 >3RWL-A nrPDB Length = 426 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 58/158 (36%), Gaps = 22/158 (13%) Query: 354 SVIKSNGGELTMGAIEKME-LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKA 412 V+ + ++ L +++V E +R++ P+ A + +S ++ Sbjct: 277 GVLALHKNPDQFAKLKANPALVETMVPEIIRWQTPLAHMRRTA----IADSELGGKTIRK 332 Query: 413 GEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCA 472 G+ + + RD ++ DR +EF+ +R + + G +C Sbjct: 333 GDKVVMWYYSGNRDDEVIDRPEEFIIDR---------------PRPRQHLSFGFGIHRCV 377 Query: 473 GKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNF 510 G + R+ EI R+ IEV P NF Sbjct: 378 GNRLAEMQLRILWEEILTRFS--RIEVMAEPERVRSNF 413 >4R20-A nrPDB Length = 486 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 78/370 (21%), Positives = 141/370 (38%), Gaps = 44/370 (11%) Query: 147 LTGGYRILSYLD--PSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKEL-SL 203 LT G + +++ D P H +L + F L N++ Q E DSL +EL + Sbjct: 97 LTQGGKDIAFADYSPLWKNHRRLVHSSFTLFGEGSNKL----QTIVQEAADSLCEELQAC 152 Query: 204 KGKA-DFGGSSDGTAFNFLARAFYGTN--PADTKLKA------DAPGLITKWVLFNLHPL 254 +G++ D N + R + ++ P+D +L+ I + L ++ P Sbjct: 153 RGQSSDLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTIARGGLVDIFPW 212 Query: 255 LSIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLE-SAGEILVEADKLGISR------ 307 L I P + L S+ L+ Y++L E + GE D L I + Sbjct: 213 LRI-FPNKDLKRLKECVSIRDQLL---YKKLLEHKKSLTPGEPRDLLDALLIGQQRGSGG 268 Query: 308 -EEATHNLLFATCFNTWG-GMKILFPNMVKRIGRAGH--QVHNRLAEEIRSVIKSNGGEL 363 ++ T + + T +G G++ ++ I H Q+ R+ E+ + + Sbjct: 269 ADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVD-RPP 327 Query: 364 TMGAIEKMELTKSVVYECLRFEPPVTAQY-GRAKKDLVIESHDAAFKVKAGEMLYGYQPL 422 + + L +V+ E +R P A +D + H V G + Sbjct: 328 CLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGH----SVPKGTRVLVNMWA 383 Query: 423 ATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVAR 482 DPK +D+ ++F PERF+ G+K G + C G+ + Sbjct: 384 IHHDPKHWDQPEQFNPERFLEPSGKK-------KTQSSFLPFGAGPRVCVGESLARIELF 436 Query: 483 LFVIEIFRRY 492 LFV +R+ Sbjct: 437 LFVSRPLQRF 446 >6AYB-A nrPDB Length = 466 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 64/164 (39%), Gaps = 12/164 (7%) Query: 340 AGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDL 399 + +V ++ +E ++ S+ L + KM+ ++ + E LR PP+ A+K Sbjct: 286 SNKKVLEKVRKEQEEIMGSDKV-LDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPR 344 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 E + + G +L +A R + D F PER + + ++ Sbjct: 345 ECEQ----YIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKY------- 393 Query: 460 ETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSP 503 G +C G++F +L + + + R +D I P Sbjct: 394 GAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDP 437 >6HQG-A nrPDB Length = 425 Score = 95.5 bits (236), Expect = 5e-20, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 58/142 (40%), Gaps = 21/142 (14%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 E L ++V E +R++ P+ RAK+D + ++ G+ + + RD + Sbjct: 290 ENPGLIPAMVSETIRWQTPLAYMRRRAKRDFEL----GGKTIREGDKVAMWYVSGNRDEE 345 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 + DR +++ ER ++ +H+ + G +C G L ++ EI Sbjct: 346 VIDRPNDYWIER------PRVRQHLSF---------GFGVHRCVGNRLAELQLKIIWEEI 390 Query: 489 FRRYDSFDIEVGTSPLGSSVNF 510 R+ +EV P +F Sbjct: 391 LARFP--RLEVVGPPRRVYSSF 410 >6C94-A nrPDB Length = 497 Score = 94.8 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 60/170 (35%), Gaps = 18/170 (10%) Query: 345 HNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESH 404 R EE+R ++ + + KM + EC R PPV Y + K + S Sbjct: 316 QQRCREEVREILG-DQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPV---SF 371 Query: 405 DAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETP 464 + AG ++ + R+ ++ + F P RF E P P Sbjct: 372 VDGRSLPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSPENSS--------GRHPYAFIP 423 Query: 465 T-VGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSL 513 G + C G+ F + ++ R++ F ++ PL + L Sbjct: 424 FSAGPRNCIGQQFAMNEMKVVTALCLLRFE-FSVD----PLRLPIKLPQL 468 >3K9V-A nrPDB Length = 482 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 15/152 (9%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 Q RL +E++SV+ + + M K+ + E +R P V K V+ Sbjct: 315 QAQRRLLQEVQSVL-PDNQTPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVL- 372 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 + + G +L + F+ + +F PER++ +E + P Sbjct: 373 ---GEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKK---------INPFAH 420 Query: 463 TP-TVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 P +G + C G+ L L + I ++YD Sbjct: 421 LPFGIGKRMCIGRRLAELQLHLALCWIIQKYD 452 >3DL9-A nrPDB Length = 479 Score = 92.1 bits (227), Expect = 6e-19, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 59/150 (39%), Gaps = 11/150 (7%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 + ++ +EI ++ NG + KM T++V++E LRF V A + + Sbjct: 305 NIQGQVQKEIDLIMGPNGKP-SWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSE---D 360 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 + + + G + D K + + F PERF+ G ++ Sbjct: 361 AVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSG-------YFAKKEALV 413 Query: 463 TPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 ++G + C G+ + LF + +R+ Sbjct: 414 PFSLGRRHCLGEHLARMEMFLFFTALLQRF 443 >3JUS-A nrPDB Length = 461 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 65/173 (37%), Gaps = 15/173 (8%) Query: 341 GHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 + + E ++V N LT ++ + L + E LR PP+ A+ Sbjct: 282 DKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQT 341 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 + A + + G + + R + +F P+R++ + + Sbjct: 342 V----AGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAY------ 391 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSL 513 G +C G++F + + + R Y+ FD+ G P +VN++++ Sbjct: 392 -VPFGAGRHRCIGENFAYVQIKTIWSTMLRLYE-FDLIDGYFP---TVNYTTM 439 >5YLW-A nrPDB Length = 495 Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 55/148 (37%), Gaps = 12/148 (8%) Query: 347 RLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY-GRAKKDLVIESHD 405 RL E++SV + + A+ K+ ++V+ E +R PP +A+ D + + Sbjct: 323 RLKAELKSV-AGDEKIVDESAMPKLPYLQAVIKEVMRIHPPGPLLLPRKAESDQEVNGYL 381 Query: 406 AAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPT 465 + G + RDP I+ + F PERF+ + + E Sbjct: 382 ----IPKGTQILINAYAIGRDPSIWTDPETFDPERFLDNKID------FKGQDYELLPFG 431 Query: 466 VGNKQCAGKDFVVLVARLFVIEIFRRYD 493 G + C G + + + +D Sbjct: 432 SGRRVCPGMPLATRILHMATATLVHNFD 459 >2WX2-A nrPDB Length = 473 Score = 90.1 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 50/267 (18%), Positives = 95/267 (35%), Gaps = 69/267 (25%) Query: 259 LPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLL--- 315 +P ++ PL + A +++ Q++ GEI+V +K S++ T +LL Sbjct: 201 MPWLLRLPLPQSARCREA--RAELQKIL-------GEIIVAREKEEASKDNNTSDLLGGL 251 Query: 316 ------------------------FA-----TCFNTWGGMKILFPNMVKRIGRAGHQVHN 346 FA T +W + ++ P K + + Sbjct: 252 LKAVYRDGTRMSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWL--------D 303 Query: 347 RLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDA 406 +L +EI + M +M + V E +R +PP+ K ++ + S Sbjct: 304 KLHKEIDEFPAQLNYDNVMD---EMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGS--- 357 Query: 407 AFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTV 466 + V G+++ L+ D + F + PER +G + Sbjct: 358 -YVVPKGDIIACSPLLSHHDEEAFPNPRLWDPERDEKVDGAFI-------------GFGA 403 Query: 467 GNKQCAGKDFVVLVARLFVIEIFRRYD 493 G +C G+ F +L + + FR YD Sbjct: 404 GVHKCIGQKFALLQVKTILATAFREYD 430 >6HQD-A nrPDB Length = 420 Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 51/138 (36%), Gaps = 21/138 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L SV+ E +R++ P+ A +D+ +++ G+ + + RD ++ DR Sbjct: 291 LLASVIPEVVRWQTPIAHMRRTALEDVEFRGK----QIRKGDKVVMWYLSGNRDDEVIDR 346 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 +F+ +R + G +C G L ++ E+ RY Sbjct: 347 PMDFIADR---------------PRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERY 391 Query: 493 DSFDIEVGTSPLGSSVNF 510 IEV P+ N Sbjct: 392 S--RIEVCGEPVRVPSNL 407 >3TKT-A nrPDB Length = 450 Score = 87.8 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 31/138 (22%), Positives = 45/138 (32%), Gaps = 22/138 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L +V E +R+ PV A D + K+ AG+ L A DP F Sbjct: 321 LLPGIVEEAIRWTTPVQHFMRTAATDTELCGQ----KIAAGDWLMLNYVAANHDPAQFPE 376 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 +F P R G+ QC G L R+ + + R Sbjct: 377 PRKFDPTR----------------PANRHLAFGAGSHQCLGLHLARLEMRVLLDVLLDRV 420 Query: 493 DSFDIEVGTSPLGSSVNF 510 DS +E+ P + F Sbjct: 421 DS--LELAGEPKRVNSTF 436 >4WMZ-A nrPDB Length = 539 Score = 87.1 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 56/156 (35%), Gaps = 11/156 (7%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V L EE V+ ELT +++M L + E LR P+ + + + KD+ + Sbjct: 336 VQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVP- 394 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERF---------VGEEGEKLLRHVL 454 + ++ + AG + + F A +F R+ VGEE + + Sbjct: 395 -NTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAIS 453 Query: 455 WSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 G +C G+ F + + R Sbjct: 454 KGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIR 489 >6M7X-A nrPDB Length = 484 Score = 86.3 bits (212), Expect = 3e-17, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 58/148 (39%), Gaps = 14/148 (9%) Query: 329 LFPNMVKRIGRAGHQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPP 387 +FP ++ A + V L +E + S A ++ L ++ + E LR P Sbjct: 297 VFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQ-KATTELPLLRAALKETLRLYPV 355 Query: 388 VTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGE 447 A DLV+++ + + AG ++ + R+P +F R + + P+R++ G Sbjct: 356 GLFLERVASSDLVLQN----YHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGS 411 Query: 448 KLLRHVLWSNGPETETPTVGNKQCAGKD 475 G +QC G+ Sbjct: 412 --------GRNFYHVPFGFGMRQCLGRR 431 >1CPT-A nrPDB Length = 428 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 50/140 (35%), Gaps = 22/140 (15%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 L +V E +R+ PV + A D + + +K G+ + P A RD ++F Sbjct: 297 PALIPRLVDEAVRWTAPVKSFMRTALADTEVRGQN----IKRGDRIMLSYPSANRDEEVF 352 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 DEF RF G C G+ L ++F E+ Sbjct: 353 SNPDEFDITRF----------------PNRHLGFGWGAHMCLGQHLAKLEMKIFFEELLP 396 Query: 491 RYDSFDIEVGTSPLGSSVNF 510 + S +E+ P + NF Sbjct: 397 KLKS--VELSGPPRLVATNF 414 >5FSA-A nrPDB Length = 490 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 57/159 (35%), Gaps = 18/159 (11%) Query: 344 VHNRLAEEIRSVIKSNGGEL---TMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 + + + +E+ ++K GG+L T ++K+ + + E LR P+ + + + L Sbjct: 287 LQDVIYQEVVELLKEKGGDLNDLTYEDLQKLPSVNNTIKETLRMHMPLHSIFRKVTNPLR 346 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERF-------------VGEEGE 447 I + + V G + A + FD ++F P R+ +E + Sbjct: 347 IPETN--YIVPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVD 404 Query: 448 KLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVI 486 V G +C G+ F + + Sbjct: 405 YGFGKVSKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILT 443 >4R1Z-A nrPDB Length = 439 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 54/151 (35%), Gaps = 11/151 (7%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQY-GRAKKDLVI 401 QV ++ EE+ S I + + ++ + E LR P A +D Sbjct: 254 QVQRKIQEELDSKIGK-ERHPQLSDRGNLPYLEATIREVLRIRPVSPLLIPHVALQD--- 309 Query: 402 ESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPET 461 S + V+ G + D K + + F P RF+ EEG+ L Sbjct: 310 -SSVGEYTVQKGTRVVINLWSLHHDKKEWKNPELFDPGRFLNEEGDGL-----CCPSGSY 363 Query: 462 ETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 G + C G+ + LF+ I +R+ Sbjct: 364 LPFGAGVRVCLGEALAKMELFLFLAWILQRF 394 >6B82-A nrPDB Length = 509 Score = 85.5 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 58/164 (35%), Gaps = 14/164 (8%) Query: 333 MVKR-IGRAGH--QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVT 389 +K I H QV ++ EE+ S I + + ++ + E +R P Sbjct: 305 TLKWSIAYLVHNPQVQRKIQEELDSKIGK-ERHPQLSDRGNLPYLEATICEVMRIRPVSP 363 Query: 390 AQY-GRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEK 448 A +D S + V+ G + D K + + F P RF+ EEG+ Sbjct: 364 LLIPHVALQD----SSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEGDG 419 Query: 449 LLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 L G + C G+ + LF+ I +R+ Sbjct: 420 L-----CCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRF 458 >3MDV-A nrPDB Length = 456 Score = 84.8 bits (208), Expect = 8e-17, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 58/147 (39%), Gaps = 14/147 (9%) Query: 347 RLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDA 406 RL E+ VI S L + +++ V+ E LR PP + +++ +I+ Sbjct: 279 RLQAEVDEVIGS-KRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG--- 334 Query: 407 AFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTV 466 +V L + R F+ F P+RF + + ++ Sbjct: 335 -VRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRFTY---------FPFSL 384 Query: 467 GNKQCAGKDFVVLVARLFVIEIFRRYD 493 G++ C G+ F + ++ + ++ +R + Sbjct: 385 GHRSCIGQQFAQMEVKVVMAKLLQRLE 411 >2X2N-A nrPDB Length = 475 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 61/172 (35%), Gaps = 28/172 (16%) Query: 322 TWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYEC 381 TW + ++ P VK + L +EI M +M + E Sbjct: 287 TWSMLHLMHPANVKHL--------EALRKEIEEFPAQLNYNNVMD---EMPFAERCARES 335 Query: 382 LRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERF 441 +R +PP+ + D+ + S + V G+++ L+ D + F + PER Sbjct: 336 IRRDPPLLMLMRKVMADVKVGS----YVVPKGDIIACSPLLSHHDEEAFPEPRRWDPERD 391 Query: 442 VGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 EG + G +C G+ F +L + + FR YD Sbjct: 392 EKVEGAFI-------------GFGAGVHKCIGQKFGLLQVKTILATAFRSYD 430 >5JLC-A nrPDB Length = 515 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 54/157 (34%), Gaps = 12/157 (7%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V L +E V+ ++ ELT ++ M L ++ E LR P+ + + + +D+ I Sbjct: 318 VQEELYQEQMRVLNNDTKELTYDDLQNMPLLNQMIKETLRLHHPLHSLFRKVMRDVAIP- 376 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKL----------LRHV 453 + ++ V + + F + +EF R+ G+ + Sbjct: 377 -NTSYVVPRDYHVLVSPGYTHLQEEFFPKPNEFNIHRWDGDAASSSAAGGDEVDYGFGAI 435 Query: 454 LWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 G +C G+ F + + R Sbjct: 436 SKGVSSPYLPFGGGRHRCIGELFAYCQLGVLMSIFIR 472 >2PG7-A nrPDB Length = 476 Score = 83.6 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 39/170 (22%), Positives = 68/170 (40%), Gaps = 17/170 (10%) Query: 342 HQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVT-AQYGRAKKDL 399 H V ++ EEI VI N + KM ++V++E RF + + R KKD Sbjct: 298 HPEVEAKVHEEIDRVIGKN-RQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKD- 355 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 + F + G +Y RDP F +F P+ F+ E+G+ + Sbjct: 356 ---TKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQ-------FKKSD 405 Query: 460 ETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVN 509 ++G + C G+ + LF + + +F ++ SP V+ Sbjct: 406 AFVPFSIGKRNCFGEGLARMELFLFFTTVMQ---NFRLKSSQSPKDIDVS 452 >3SN5-A nrPDB Length = 491 Score = 83.2 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 65/160 (40%), Gaps = 12/160 (7%) Query: 350 EEIRSVIKSNGGELTMG---------AIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 EE++ +++ G ++++ + + + S++ E LR AK+D Sbjct: 296 EEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSSASLNI-RTAKEDFT 354 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 + D ++ ++ +++ Y L DP+I+ F +R++ E G+ + Sbjct: 355 LHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLK 414 Query: 461 TE--TPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIE 498 G C G+ F + + F+I + ++ IE Sbjct: 415 YYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIE 454 >3QZ1-A nrPDB Length = 496 Score = 83.2 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 57/167 (34%), Gaps = 21/167 (12%) Query: 342 HQ-VHNRLAEEIRSVIKSNGG--ELTMGAIEKMELTKSVVYECLRFEP--PVTAQYGRAK 396 H + RL EE+ + +T ++ L + + E LR P P+ + + Sbjct: 309 HPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTR 368 Query: 397 KDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWS 456 S + + G ++ A D ++++ EF P+RF+ Sbjct: 369 P-----SSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGA---------- 413 Query: 457 NGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSP 503 P G + C G+ L + + + + + VG P Sbjct: 414 -NPSALAFGCGARVCLGESLARLELFVVLARLLQAFTLLPPPVGALP 459 >5H1Z-A nrPDB Length = 407 Score = 82.8 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 21/140 (15%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 + + V E +R++ P+ A D +E ++KAG+ L + A RD +F Sbjct: 275 PSMIPNTVQEIIRWQTPLAHMRRTATVDSELEGQ----QIKAGDKLALWYISANRDESVF 330 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 + AD + +R RH+ + G +C G L + + E+ + Sbjct: 331 ENADRIIVDR------PNARRHLAF---------GHGIHRCVGARLAELQIAVLLEEMAK 375 Query: 491 RYDSFDIEVGTSPLGSSVNF 510 R + V P + F Sbjct: 376 R--RMRVNVLGEPERVAACF 393 >6CR2-A nrPDB Length = 477 Score = 82.8 bits (203), Expect = 4e-16, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 57/158 (36%), Gaps = 11/158 (6%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 + L +E V+ S+ LT ++K++L V+ E LR P+ + K + ++ Sbjct: 283 IMEELYQEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRLHAPIHSIIRAVKNPMAVDG 342 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERF------VGEEGEKL---LRHVL 454 ++ + + + R + F E+ P R+ E+ EK+ V Sbjct: 343 --TSYVIPTSHNVLSSPGVTARSEEHFPNPLEWNPHRWDENIAASAEDDEKVDYGYGLVS 400 Query: 455 WSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 G +C G+ F L + R + Sbjct: 401 KGTNSPYLPFGAGRHRCIGEQFAYLQLGTITAVLVRLF 438 >3E6I-A nrPDB Length = 476 Score = 82.4 bits (202), Expect = 5e-16, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 61/152 (40%), Gaps = 13/152 (8%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTA-QYGRAKKDLVI 401 ++ +L EEI VI + + ++M +VV+E RF V + A +D + Sbjct: 299 EIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIF 357 Query: 402 ESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPET 461 + + G ++ D + F ++F PE F+ E G+ + Sbjct: 358 RGYL----IPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGK-------FKYSDYF 406 Query: 462 ETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 + + G + CAG+ + L + I + ++ Sbjct: 407 KPFSTGKRVCAGEGLARMELFLLLCAILQHFN 438 >4KPA-A nrPDB Length = 494 Score = 82.1 bits (201), Expect = 5e-16, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 68/162 (41%), Gaps = 22/162 (13%) Query: 363 LTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPL 422 + +++++ V+ E LR P A AK+D V+ + ++ G+ L P Sbjct: 327 PSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGE---YPLEKGDELMVLIPQ 383 Query: 423 ATRDPKIF-DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVA 481 RD I+ D +EF PERF + +H + G + C G+ F + A Sbjct: 384 LHRDKTIWGDDVEEFRPERFENPSA--IPQHAF-------KPFGNGQRACIGQQFALHEA 434 Query: 482 RLFVIEIFRRYD-----SFDIEVGTS----PLGSSVNFSSLR 514 L + + + +D ++++++ + P G V S + Sbjct: 435 TLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKK 476 >4ZGX-A nrPDB Length = 489 Score = 81.7 bits (200), Expect = 8e-16, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 57/147 (38%), Gaps = 14/147 (9%) Query: 330 FPNMVKRIGRAGHQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPV 388 FP ++ A + V L +E + S A ++ L ++ + E LR P Sbjct: 298 FPLLMTLFELARNPDVQQILRQESLAAAASISEHPQ-KATTELPLLRAALKETLRLYPVG 356 Query: 389 TAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEK 448 DLV+++ + + AG ++ + R+ +F R + + P+R++ G Sbjct: 357 LFLERVVSSDLVLQN----YHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSG 412 Query: 449 LLRHVLWSNGPETETPTVGNKQCAGKD 475 H + G +QC G+ Sbjct: 413 RNFHHV--------PFGFGMRQCLGRR 431 >3S79-A nrPDB Length = 503 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 46/214 (21%), Positives = 95/214 (44%), Gaps = 23/214 (10%) Query: 280 SDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGR 339 S ++L E ++ A E+++ A+K G E + + M + M+ I Sbjct: 267 STEEKLEEC-MDFATELIL-AEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLI-- 322 Query: 340 AGHQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKD 398 A H V + +EI++VI ++ + I+K+++ ++ +YE +R++P V +A +D Sbjct: 323 AKHPNVEEAIIKEIQTVI--GERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALED 380 Query: 399 LVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNG 458 VI+ + VK G + R + F + +EF E F + + Sbjct: 381 DVIDG----YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENF----AKNVPYR------ 425 Query: 459 PETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 + G + CAGK +++ + ++ + RR+ Sbjct: 426 -YFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458 >1N6B-A nrPDB Length = 473 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 52/152 (34%), Gaps = 12/152 (7%) Query: 342 HQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 H V R+ EEI VI + M +M T +V++E RF + A + Sbjct: 295 HPEVAARVQEEIERVIGRH-RSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHA---VT 350 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 + + + G + D K F F P F+ E G + Sbjct: 351 RDVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGN-------FKKSDY 403 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 + G + C G+ + LF+ I + + Sbjct: 404 FMPFSAGKRMCVGEGLARMELFLFLTSILQNF 435 >5VBU-A nrPDB Length = 476 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 40/224 (17%), Positives = 76/224 (33%), Gaps = 28/224 (12%) Query: 276 ALVKSDYQRLYEFFLE-SAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMV 334 +LV ++ + ++ L+ A + E G E H A GG + N + Sbjct: 229 SLVAGQWRDMMDYMLQGVAQPSMEEGS--GQLLEGHVH---MAAVDLLIGGTETT-ANTL 282 Query: 335 KR--IGRAGHQ-VHNRLAEEIRSVIKSNGGE--LTMGAIEKMELTKSVVYECLRFEPPVT 389 + H + RL EE+ + + ++ L + + E LR P V Sbjct: 283 SWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVP 342 Query: 390 -AQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEK 448 A R + I +D + G ++ A D +++R EF P+RF+ Sbjct: 343 LALPHRTTRPSSISGYD----IPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNS 398 Query: 449 LLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 G + C G+ L + + + + + Sbjct: 399 -----------RALAFGCGARVCLGEPLARLELFVVLTRLLQAF 431 >6HQW-A nrPDB Length = 445 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 30/138 (21%), Positives = 52/138 (37%), Gaps = 21/138 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L + V EC+R+ P+ A D + + ++KAGE + + A RD +F+ Sbjct: 315 LIPNAVQECIRYVTPLAHMRRTATADTELFGN----QIKAGEKVILWYISANRDETVFEN 370 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 D+ + +R RH+ + G +C G L R+ + E+ R Sbjct: 371 PDKLMVDR------PNARRHLSF---------GHGIHRCVGARLAELQLRILLEEMHER- 414 Query: 493 DSFDIEVGTSPLGSSVNF 510 + V NF Sbjct: 415 -RMRVRVAGEVERVRANF 431 >5LIE-A nrPDB Length = 414 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 69/375 (18%), Positives = 132/375 (35%), Gaps = 57/375 (15%) Query: 137 FTGTYMPSTELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDS 196 F GT + + G ++L+ +D +P+H +++ L+ + + P + Sbjct: 80 FGGTVLQDLPVAG--QVLNMMD--DPRHTRIRRLV-------SSGLTPR-------MIRR 121 Query: 197 LEKELSLKGKADFGGSSDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLS 256 +E +L + + G G F+F+ + P W+ + P Sbjct: 122 VEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEPGFD 181 Query: 257 IGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLE-SAGEILVEADKLGISREEATHNLL 315 R P ++ V+ RLY + LE AG+ AD + AT + Sbjct: 182 FRGSRRATMPRLN--------VEDAGSRLYTYALELIAGKRAEPADDMLSVVANATIDDP 233 Query: 316 FATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEK-MELT 374 A + LF +++ G N +A + ++ + + EL Sbjct: 234 DAPALSD--AELYLFFHLLFSAG--AETTRNSIAGGLLAL---AENPDQLQTLRSDFELL 286 Query: 375 KSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRAD 434 + + E +R+ P ++ A + + + ++AG+ + ++ A RDP +FDRAD Sbjct: 287 PTAIEEIVRWTSPSPSKRRTASRAVSLGGQP----IEAGQKVVVWEGSANRDPSVFDRAD 342 Query: 435 EFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDS 494 EF R G C G + L R+ E+ R+ S Sbjct: 343 EFDITR----------------KPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGS 386 Query: 495 FDIEVGTSPLGSSVN 509 + V + N Sbjct: 387 --VRVVEPAEWTRSN 399 >3L4D-A nrPDB Length = 453 Score = 80.1 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 45/268 (16%), Positives = 89/268 (33%), Gaps = 70/268 (26%) Query: 259 LPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLL--- 315 LP +++ PL ++ A + + EI++ +K ++ T +LL Sbjct: 187 LPWILKLPLPQSYRCRDARAE---------LQDILSEIIIAREKEEAQKDTNTSDLLAGL 237 Query: 316 ------------------------FA-----TCFNTWGGMKILFPNMVKRIGRAGHQVHN 346 FA T TW + ++ P + + Sbjct: 238 LGAVYRDGTRMSQHEVCGMIVAAMFAGQHTSTITTTWSLLHLMDPRNKRHLA-------- 289 Query: 347 RLAEEIRSVIKSNGGELTMGAI-EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHD 405 +L +EI +L + E+M + E +R +PP+ + K + Sbjct: 290 KLHQEIDEF----PAQLNYDNVMEEMPFAEQCARESIRRDPPLVMLMRKVLKPV----QV 341 Query: 406 AAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPT 465 + V G+++ L+ +D + F E+ PER + Sbjct: 342 GKYVVPEGDIIACSPLLSHQDEEAFPNPREWNPER------------NMKLVDGAFCGFG 389 Query: 466 VGNKQCAGKDFVVLVARLFVIEIFRRYD 493 G +C G+ F +L + + + R YD Sbjct: 390 AGVHKCIGEKFGLLQVKTVLATVLRDYD 417 >5UYS-A nrPDB Length = 494 Score = 80.1 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 57/151 (37%), Gaps = 9/151 (5%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 QV +L EEI + T+ ++ L ++ + E LR P ++ Sbjct: 305 QVKKKLYEEIDQNVG-FSRTPTISDRNRLLLLEATIREVLRLRPVAPMLI---PHKANVD 360 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 S F V G + + K + + D+F+PERF+ G +L+ S Sbjct: 361 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLI-----SPSVSYL 415 Query: 463 TPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 G + C G+ L + + +R+D Sbjct: 416 PFGAGPRSCIGEILARQELFLIMAWLLQRFD 446 >3TBG-A nrPDB Length = 479 Score = 79.7 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 65/178 (36%), Gaps = 15/178 (8%) Query: 342 HQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTA-QYGRAKKDL 399 H V R+ +EI VI MG M T +V++E RF V +D+ Sbjct: 302 HPDVQRRVQQEIDDVIGQVRRP-EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 360 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 ++ F++ G L +D ++++ F PE F+ +G + Sbjct: 361 EVQG----FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGH-------FVKPE 409 Query: 460 ETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSLRKAS 517 + G + C G+ + LF + + + SF + G F+ L S Sbjct: 410 AFLPFSAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTGQPRPSHHGVFAFLVSPS 466 >6IQ5-A nrPDB Length = 463 Score = 79.7 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 32/183 (17%), Positives = 69/183 (37%), Gaps = 18/183 (9%) Query: 317 ATCFNTWGGMKILFPNMVKRIGR--AGHQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMEL 373 AT + +G + ++ + + V R+ E+ V+ + MG + Sbjct: 255 ATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRD-RLPCMGDQPNLPY 313 Query: 374 TKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 + +YE +RF V A + + + +++ Q DP + Sbjct: 314 VLAFLYEAMRFSSFVPVTIPHA---TTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNP 370 Query: 434 DEFVPERFVGEEG---EKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 + F P RF+ ++G + L V+ +VG ++C G++ + LF+ + Sbjct: 371 ENFDPARFLDKDGLINKDLTSRVM--------IFSVGKRRCIGEELSKMQLFLFISILAH 422 Query: 491 RYD 493 + D Sbjct: 423 QCD 425 >5W0C-A nrPDB Length = 477 Score = 79.7 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 53/153 (34%), Gaps = 12/153 (7%) Query: 342 HQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 H V ++ EEI VI N M M T +VV+E R+ + A + Sbjct: 299 HPEVTAKVQEEIERVIGRN-RSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHA---VT 354 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 + + + G + D K F + F P F+ E G + Sbjct: 355 CDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGN-------FKKSKY 407 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 + G + C G+ + LF+ I + ++ Sbjct: 408 FMPFSAGKRICVGEALAGMELFLFLTSILQNFN 440 >4H1N-A nrPDB Length = 479 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 52/149 (34%), Gaps = 11/149 (7%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V R+ +EI VI S+ + KM T +V++E R + + ++ Sbjct: 301 VTERVQKEIEQVIGSH-RPPALDDRAKMPYTDAVIHEIQRLGDLIPF---GVPHTVTKDT 356 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETET 463 + + ++ A DP+ F+ + F P F+ G Sbjct: 357 QFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFM-------P 409 Query: 464 PTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 ++G + C G+ LF I + + Sbjct: 410 FSLGKRICLGEGIARTELFLFFTTILQNF 438 >5E0E-A nrPDB Length = 463 Score = 79.0 bits (193), Expect = 5e-15, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 59/149 (39%), Gaps = 11/149 (7%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V ++ +EI VI S+ T+ KM T++V+YE RF + G K + ++ Sbjct: 292 VAEKVQKEIDQVIGSH-RLPTLEDRTKMPYTEAVIYEIQRFSDLIPI--GVPHK-VTKDT 347 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETET 463 + + +Y A DP+ F++ D F P+ F+ G Sbjct: 348 LFRGYLLPKNTEVYPILSSALHDPQYFEQPDTFNPDHFLDANGALKKSEAFM-------P 400 Query: 464 PTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 ++G + C G+ LF I + + Sbjct: 401 FSIGKRICLGEGIARNELFLFFTTILQNF 429 >4RM4-A nrPDB Length = 396 Score = 78.6 bits (192), Expect = 6e-15, Method: Composition-based stats. Identities = 30/138 (21%), Positives = 41/138 (29%), Gaps = 21/138 (15%) Query: 360 GGELTMGAIEK-MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 + EL V E LRF P AK+D I H +K G+M+ Sbjct: 257 ETPGVYEELRSHPELMPQAVEEALRFRAPAPVLRRIAKRDTEIGGHL----IKEGDMVLA 312 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVV 478 + A RD FDR F R P G C G Sbjct: 313 FVASANRDEAKFDRPHMFDIRR---------------HPNPHI-AFGHGIHFCLGAPLAR 356 Query: 479 LVARLFVIEIFRRYDSFD 496 L A + + + + + Sbjct: 357 LEANIALTSLISAFPHME 374 >4GQS-A nrPDB Length = 477 Score = 78.2 bits (191), Expect = 7e-15, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 53/153 (34%), Gaps = 12/153 (7%) Query: 342 HQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 H V ++ EEI V+ N M M T +VV+E R+ + A + Sbjct: 299 HPEVTAKVQEEIERVVGRN-RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHA---VT 354 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 + + + G + D K F + F P F+ E G + Sbjct: 355 CDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN-------FKKSNY 407 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 + G + C G+ + LF+ I + ++ Sbjct: 408 FMPFSAGKRICVGEGLARMELFLFLTFILQNFN 440 >6DWN-A nrPDB Length = 491 Score = 78.2 bits (191), Expect = 8e-15, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 64/168 (38%), Gaps = 15/168 (8%) Query: 344 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIES 403 V ++ EE+ +VI + + + ++ + E R V ++ Sbjct: 312 VQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPF---TIPHSTTRDT 367 Query: 404 HDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETET 463 F + G ++ Q D K++ EF+PERF+ +G + + Sbjct: 368 SLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA-----IDKVLSEKVII 422 Query: 464 PTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFS 511 +G ++C G+ LF+ + +R + F + PLG V+ + Sbjct: 423 FGMGKRKCIGETIARWEVFLFLAILLQRVE-FSV-----PLGVKVDMT 464 >2NNH-A nrPDB Length = 476 Score = 78.2 bits (191), Expect = 9e-15, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 56/158 (35%), Gaps = 12/158 (7%) Query: 342 HQ-VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLV 400 H V ++ EEI VI + M M T +VV+E R+ V + Sbjct: 298 HPEVTAKVQEEIDHVIGRH-RSPCMQDRSHMPYTDAVVHEIQRYSDLVPT---GVPHAVT 353 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 ++ + + G + D K F + F P F+ + G + Sbjct: 354 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN-------FKKSDY 406 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIE 498 + G + CAG+ + LF+ I + ++ ++ Sbjct: 407 FMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 444 >5E58-A nrPDB Length = 493 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 67/183 (36%), Gaps = 16/183 (8%) Query: 310 ATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIE 369 + +L FA T ++ F M+K V ++ +EI VI S+ T+ Sbjct: 291 SVLSLFFAGTETTSTTLRYGFLLMLKY-----PHVAEKVQKEIDQVIGSH-RLPTLEDRT 344 Query: 370 KMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 KM T +V++E RF A + ++ + + +Y A DP+ Sbjct: 345 KMPYTDAVIHEIQRFSDLAPI---GAPHKVTKDTLFRGYLLPKNTEVYPILSSALHDPQY 401 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 F++ F P+ F+ G ++G + C G+ LF I Sbjct: 402 FEQPGTFNPDHFLDANGALKKSEAFM-------PFSIGKRICLGEGIARNELFLFFTTIL 454 Query: 490 RRY 492 + + Sbjct: 455 QNF 457 >3IBD-A nrPDB Length = 476 Score = 76.7 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 38/182 (20%), Positives = 65/182 (35%), Gaps = 16/182 (8%) Query: 311 THNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEK 370 T +L FA T ++ F M+K V R+ EI VI + + K Sbjct: 273 TLSLFFAGTETTSTTLRYGFLLMLKY-----PHVAERVYREIEQVIGPH-RPPELHDRAK 326 Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 M T++V+YE RF + G + + + + ++ A DP F Sbjct: 327 MPYTEAVIYEIQRFSDLLP--MGVPHI-VTQHTSFRGYIIPKDTEVFLILSTALHDPHYF 383 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 ++ D F P+ F+ G ++G + C G+ LF I + Sbjct: 384 EKPDAFNPDHFLDANGALKKTEAFI-------PFSLGKRICLGEGIARAELFLFFTTILQ 436 Query: 491 RY 492 + Sbjct: 437 NF 438 >2HI4-A nrPDB Length = 495 Score = 76.7 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 67/172 (38%), Gaps = 20/172 (11%) Query: 343 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLR---FEPPVTAQYGRAKKDL 399 ++ ++ +E+ +VI + ++ ++ + E R F P Sbjct: 314 EIQRKIQKELDTVIGRERRP-RLSDRPQLPYLEAFILETFRHSSFLPFTIP------HST 366 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 ++ F + ++ Q DP++++ EF PERF+ +G + + + Sbjct: 367 TRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLS----E 422 Query: 460 ETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFS 511 + +G ++C G+ LF+ + ++ + F + P G V+ + Sbjct: 423 KMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLE-FSV-----PPGVKVDLT 468 >3MGX-A nrPDB Length = 415 Score = 74.4 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 41/125 (32%), Gaps = 20/125 (16%) Query: 374 TKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 +VV E LR+ P D+ I D + +G + + P A RDP FD Sbjct: 287 VDTVVEEVLRWTSPAMHVLRVTTADVTINGRD----LPSGTPVVAWLPAANRDPAEFDDP 342 Query: 434 DEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 D F+P R T G C G + + + + R Sbjct: 343 DTFLPGR----------------KPNRHITFGHGMHHCLGSALARIELSVVLRVLAERVS 386 Query: 494 SFDIE 498 D+E Sbjct: 387 RVDLE 391 >2WIO-A nrPDB Length = 431 Score = 72.0 bits (175), Expect = 6e-13, Method: Composition-based stats. Identities = 36/168 (21%), Positives = 51/168 (30%), Gaps = 21/168 (12%) Query: 339 RAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKME-LTKSVVYECLRFEPPVTAQYGRAKK 397 AGH L I V + A + ++V E LR+ PP K Sbjct: 260 LAGHITTTVLLGNI--VRTLDEHPAHWDAAAEDPGRIPAIVEEVLRYRPPFPQMQRTTTK 317 Query: 398 DLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSN 457 + A + A M+ + A RD D D F P R G Sbjct: 318 ATEV----AGVPIPADVMVNTWVLSANRDSDAHDDPDRFDPSRKSG-------------- 359 Query: 458 GPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLG 505 G + G C G L R+ + EI R+ ++ L Sbjct: 360 GAAQLSFGHGVHFCLGAPLARLENRVALEEIIARFGRLTVDRDDERLR 407 >5L94-A nrPDB Length = 410 Score = 71.7 bits (174), Expect = 7e-13, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 50/128 (39%), Gaps = 20/128 (15%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 + EL S + E LR+ PV A + K+D+ + A K+KAGE + + A RD + Sbjct: 270 REKELLPSGIEEVLRYRSPVQALHRIVKEDVTL----AGKKLKAGEHVVPWMGSAHRDAE 325 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 F+ + F +R G C G + A++ + E+ Sbjct: 326 YFEDPEVFKIDR----------------KPNVHMAFGRGIHFCLGAPLARIEAKIMLAEL 369 Query: 489 FRRYDSFD 496 RY D Sbjct: 370 IDRYPQMD 377 >1UE8-A nrPDB Length = 367 Score = 71.7 bits (174), Expect = 8e-13, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 45/120 (37%), Gaps = 20/120 (16%) Query: 378 VYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFV 437 V E LRF PPV K+ + I + GE++ + A RD ++F D F+ Sbjct: 244 VEEALRFSPPVMRTIRVTKEKVKIRDQV----IDEGELVRVWIASANRDEEVFKDPDSFI 299 Query: 438 PERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDI 497 P+R + G C G L AR+ + E +++ +I Sbjct: 300 PDR----------------TPNPHLSFGSGIHLCLGAPLARLEARIALEEFAKKFRVKEI 343 >6GII-A nrPDB Length = 479 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 49/148 (33%), Gaps = 27/148 (18%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 L + ECLR+ PV R +++ +E ++ G + A D F Sbjct: 338 PSLIPAAAEECLRYNGPVAGWRRRTTREVEVEG----VRLPVGANILMVVASANHDSAHF 393 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 D + F R SN E G QC G++ + ++ + E+ R Sbjct: 394 DDPEFFDIGR---------------SNASEHLNFGYGAHQCLGRNLGRMEMQIMIEELSR 438 Query: 491 RYDSFDIEVGTSPLGSSVNFSSLRKASF 518 R + + F L SF Sbjct: 439 RLPHMRL--------AEQRFDYLHNVSF 458 >1F4U-A nrPDB Length = 368 Score = 69.3 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 48/120 (40%), Gaps = 20/120 (16%) Query: 378 VYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFV 437 + E LR+ PPV + K+ + + ++ GE + + A RD ++F ++F+ Sbjct: 244 IEEALRYSPPVMRTVRKTKERVKLGDQ----TIEEGEYVRVWIASANRDEEVFHDGEKFI 299 Query: 438 PERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDI 497 P+R N + G C G L AR+ + E +R+ +I Sbjct: 300 PDR----------------NPNPHLSFGSGIHLCLGAPLARLEARIAIEEFSKRFRHIEI 343 >5OFQ-A nrPDB Length = 409 Score = 69.3 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 46/130 (35%), Gaps = 20/130 (15%) Query: 362 ELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQP 421 ++ + L ++V E LR+ PP+ A A +D+ + K+K G+ + + Sbjct: 262 DVQNEVRRDISLVPNLVEETLRYYPPIQAIGRIAAEDVEL----GECKIKRGQQVISWAA 317 Query: 422 LATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVA 481 A RD F+ D FV R + G C G + Sbjct: 318 SANRDSAKFEWPDTFVVHRKTNPH----------------VSFGFGIHFCLGAPLARMEG 361 Query: 482 RLFVIEIFRR 491 ++ ++ + Sbjct: 362 KIAFTKLLEK 371 >2WIY-A nrPDB Length = 394 Score = 67.4 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 51/136 (37%), Gaps = 20/136 (14%) Query: 376 SVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADE 435 +++ E +R +PP + +D+ I ++AG + A RDP++FD D Sbjct: 268 AIINEMVRMDPPQLSFLRFPTEDVEI----GGVLIEAGSPIRFMIGAANRDPEVFDDPDV 323 Query: 436 FVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSF 495 F R L + +G CAG+ A + RY+ Sbjct: 324 FDHTR-PPAASRNL-------------SFGLGPHSCAGQIISRAEATTVFAVLAERYE-- 367 Query: 496 DIEVGTSPLGSSVNFS 511 IE+ P + +F+ Sbjct: 368 RIELAEEPTVAHNDFA 383 >5DE9-A nrPDB Length = 410 Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 46/135 (34%), Gaps = 22/135 (16%) Query: 370 KMELTKSVVYECLRFEP--PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 + E+ + E LR+ P A +D+ I+ +++AG+ +Y A RDP Sbjct: 270 EPEIRPRAIDELLRWIPHRNAVGLSRIALEDVEIKG----VRIRAGDAVYVSYLAANRDP 325 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 ++F D ER + + G C G L + L V Sbjct: 326 EVFPDPDRIDFER----------------SPNPHVSFGFGPHYCPGGMLARLESELLVDA 369 Query: 488 IFRRYDSFDIEVGTS 502 + R + V Sbjct: 370 VLDRVPGLKLAVAPE 384 >6B11-A nrPDB Length = 440 Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 41/126 (32%), Gaps = 20/126 (15%) Query: 366 GAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATR 425 L V E LR+ A D+ I+ H ++AG+ L A R Sbjct: 304 ELTVNPGLLPGAVDELLRYLSIADGLRRSATADIEIDGH----TIRAGDGLVFLLAAANR 359 Query: 426 DPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFV 485 D +F + F R RHV + G QC G++ + + + Sbjct: 360 DEAVFSEPEAFDIHR-------SARRHVAF---------GYGPHQCLGQNLARMELEVAL 403 Query: 486 IEIFRR 491 + R Sbjct: 404 GAVLER 409 >5M0P-A nrPDB Length = 428 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 37/151 (24%), Positives = 55/151 (36%), Gaps = 25/151 (16%) Query: 359 NGGELTMGAIE-KMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLY 417 N +T I+ + + E R+ P V G+AK D+ + AG L Sbjct: 268 NENPITREKIKSEPDYAYKFAQEVRRYYPFVPFLPGKAKVDID----FQGVTIPAGVGLA 323 Query: 418 GYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVG-----NKQCA 472 T D ++D +EF PERF W P P G N +CA Sbjct: 324 LDVYGTTHDESLWDDPNEFRPERFE-----------TWDGSPFDLIPQGGGDYWTNHRCA 372 Query: 473 GKDFVVLV----ARLFVIEIFRRYDSFDIEV 499 G+ V++ + F +I D+EV Sbjct: 373 GEWITVIIMEETMKYFAEKITYDVPEQDLEV 403 >3NC3-A nrPDB Length = 441 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 46/126 (36%), Gaps = 10/126 (7%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L + E LR++PPV + +D V+ ++K +++ A RDP+ F++ Sbjct: 301 LVPRAIAETLRYKPPVQLIPRQLSQDTVV----GGMEIKKDTIVFCMIGAANRDPEAFEQ 356 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 D F R E L +S G C G F + + + Sbjct: 357 PDVFNIHR------EDLGIKSAFSGAARHLAFGSGIHNCVGTAFAKNEIEIVANIVLDKM 410 Query: 493 DSFDIE 498 + +E Sbjct: 411 RNIRLE 416 >4OQR-A nrPDB Length = 457 Score = 66.3 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 52/146 (35%), Gaps = 26/146 (17%) Query: 364 TMGAIEKMELTKSV-----VYECLRFEPPV--TAQYGRAKKDLVIESHDAAFKVKAGEML 416 T ++ E ++ V E LR+ V A +D+ +E ++ G+ + Sbjct: 292 TFALLQHPEQIANLDSPDAVEELLRYLSIVHLGTPNRAALEDVELEGQM----IRKGDTV 347 Query: 417 YGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDF 476 P RDPK+FD D +R +H + G QC G+ Sbjct: 348 AIGLPAVNRDPKVFDEPDILQLDRV------DARKHAAF---------GGGIHQCLGQQL 392 Query: 477 VVLVARLFVIEIFRRYDSFDIEVGTS 502 + R+ +F R+ S + V Sbjct: 393 ARVEMRIGFTRLFARFPSLRLAVPAE 418 >3R9C-A nrPDB Length = 418 Score = 65.9 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 20/117 (17%) Query: 376 SVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADE 435 +V+ E +R++PPV A DL I +H V G+ + A RDP I D Sbjct: 291 AVIEETMRYDPPVQLVSRYAGDDLTIGTH----TVPKGDTMLLLLAAAHRDPTIVGAPDR 346 Query: 436 FVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 F P+R +RH+ + G C G L A + + + R+ Sbjct: 347 FDPDR-------AQIRHLGF---------GKGAHFCLGAPLARLEATVALPALAARF 387 >2IAG-A nrPDB Length = 482 Score = 65.9 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 61/168 (36%), Gaps = 15/168 (8%) Query: 348 LAEEIRSVIKSNGGELTM------GAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVI 401 + E+ S++ ++ ++ + SV+ E LR DL + Sbjct: 287 VRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRL-TAAPFITREVVVDLAM 345 Query: 402 ESHDA-AFKVKAGEMLYGYQPLA-TRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSN-- 457 D F ++ G+ L + L+ RDP+I+ + F RF+ +G + Sbjct: 346 PMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRL 405 Query: 458 GPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD----SFDIEVGT 501 G+ C G+ + V + FV + D + D+E+ Sbjct: 406 KNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPE 453 >1WIY-A nrPDB Length = 389 Score = 65.5 bits (158), Expect = 6e-11, Method: Composition-based stats. Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 15/114 (13%) Query: 379 YECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVP 438 E LR PP R ++ L++ ++ G L + R F + F P Sbjct: 259 QEALRLYPPAWILTRRLERPLLLGED----RLPQGTTLVLSPYVTQR--LYFPEGEAFQP 312 Query: 439 ERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 ERF+ E G R+ +G + C G+DF +L + + FRR+ Sbjct: 313 ERFLAERGTPSGRY---------FPFGLGQRLCLGRDFALLEGPIVLRAFFRRF 357 >3P3Z-A nrPDB Length = 416 Score = 65.1 bits (157), Expect = 7e-11, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 42/130 (32%), Gaps = 20/130 (15%) Query: 369 EKMELTKSVVYECLRFEPPVTAQ-YGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 E EL V E LR+ P + A +D + ++ G ++ +A RDP Sbjct: 281 ENPELAPQAVEEVLRWSPTLPVTATRVAAEDFEVNG----VRIPTGTPVFMCAHVAHRDP 336 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 ++F AD F V E + G C G L V Sbjct: 337 RVFADADRFDIT--VKREAPSI-------------AFGGGPHFCLGTALARLELTEAVAA 381 Query: 488 IFRRYDSFDI 497 + R D I Sbjct: 382 LATRLDPPQI 391 >4PWV-A nrPDB Length = 446 Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 41/137 (29%), Gaps = 22/137 (16%) Query: 374 TKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 +S E LR+ P RA D+ + + AG+++ + A RD ++F Sbjct: 303 LESATEEVLRWATPAMHFGRRAVTDMELHGQV----IAAGDVVTLWNNSANRDEEVFADP 358 Query: 434 DEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 F R + + T G C G + + Sbjct: 359 YAFDLNR----------------SPNKHITFGYGPHFCLGAYLGRAEVHALLDALRTYTT 402 Query: 494 SFDIEVGTSPLGSSVNF 510 F E+ P NF Sbjct: 403 GF--EITGEPQRIHSNF 417 >4Z5P-A nrPDB Length = 400 Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 43/133 (32%), Gaps = 22/133 (16%) Query: 369 EKMELTKSVVYECLRFEPPV--TAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRD 426 E+ EL V E LRF P A +D+ + + V+AGE + A RD Sbjct: 265 EQPELLPRAVEELLRFVPLGNGVGNARIALEDVEL----SGGTVRAGEGVVAAAVNANRD 320 Query: 427 PKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVI 486 P+ FD D R G C G + R+ + Sbjct: 321 PRAFDDPDRLDITREKNPHLA----------------FGHGAHYCLGAQLARMELRVAIG 364 Query: 487 EIFRRYDSFDIEV 499 + R+ + V Sbjct: 365 GLLERFPGLRLAV 377 >4OQS-A nrPDB Length = 433 Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 50/146 (34%), Gaps = 26/146 (17%) Query: 364 TMGAIEKMELT-----KSVVYECLRFEPPV--TAQYGRAKKDLVIESHDAAFKVKAGEML 416 T ++ E V E LR+ V A +D+ +E ++ G+ + Sbjct: 253 TFALLQHPEQIAALDSPDAVEELLRYLSIVHLGTPNRAALEDVELEGQM----IRKGDTV 308 Query: 417 YGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDF 476 P RDPK+FD D +R +H + G QC G+ Sbjct: 309 AIGLPAVNRDPKVFDEPDILQLDRV------DARKHAAF---------GGGIHQCLGQQL 353 Query: 477 VVLVARLFVIEIFRRYDSFDIEVGTS 502 + R+ +F R+ S + V Sbjct: 354 ARVEMRIGFTRLFARFPSLRLAVPAE 379 >5FOI-A nrPDB Length = 408 Score = 64.7 bits (156), Expect = 8e-11, Method: Composition-based stats. Identities = 32/147 (21%), Positives = 50/147 (34%), Gaps = 22/147 (14%) Query: 362 ELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQP 421 E E+ EL + V E LR+ A D+V+ H ++AG+ L Sbjct: 268 ETAAELREQPELMPNAVDELLRYHSIADGLRRAATADIVLGDH----TIRAGDGLIILLS 323 Query: 422 LATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVA 481 A D F F R HV + G QC G++ L Sbjct: 324 SANHDGNTFGAEATFDIHR-------PARHHVAF---------GYGPHQCLGQNLARLEM 367 Query: 482 RLFVIEIFRRYDSFDIEVGTSPLGSSV 508 + + ++FRR + + + P V Sbjct: 368 EVTLGKLFRRVPA--LRLAQEPDALRV 392 >3AWQ-A nrPDB Length = 415 Score = 64.7 bits (156), Expect = 9e-11, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 43/135 (31%), Gaps = 21/135 (15%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 +++ + + V E RF P A RA +D E G + + D Sbjct: 268 VQQPDYAELFVQEVRRFYPFFPAVVARASQDFEWEG----MAFPEGRQVVLDLYGSNHDA 323 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVG-----NKQCAGKDFVVLVAR 482 + EF PERF W P G +C G+ V+ + + Sbjct: 324 ATWADPQEFRPERF-----------RAWDEDSFNFIPQGGGDHYLGHRCPGEWIVLAIMK 372 Query: 483 LFVIEIFRRYDSFDI 497 + + +D+ Sbjct: 373 VA-AHLLVNAMRYDV 386 >3EJB-B nrPDB Length = 404 Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 31/129 (24%), Positives = 49/129 (37%), Gaps = 20/129 (15%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 E +L + V ECLR+E P A +D+ I ++ GE +Y A RDP Sbjct: 262 ENPDLIGTAVEECLRYESPTQMTARVASEDIDI----CGVTIRQGEQVYLLLGAANRDPS 317 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 IF D F R + + G+ C G L A++ + + Sbjct: 318 IFTNPDVFDITR----------------SPNPHLSFGHGHHVCLGSSLARLEAQIAINTL 361 Query: 489 FRRYDSFDI 497 +R S ++ Sbjct: 362 LQRMPSLNL 370 >4GGV-A nrPDB Length = 418 Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 40/131 (30%), Gaps = 20/131 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L + E LR P A +++ + A + +++ + RDP+ F Sbjct: 289 LVPGAIEEALRVLSPSAALARGTSREVEV----AGTVIPKDQIVMLWLGAGNRDPRQFTD 344 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 + + P R + G C G L R+ + +F R+ Sbjct: 345 PEVYDPTR----------------DPNPHFGFGRGIHFCLGAPLARLEGRVALNALFDRF 388 Query: 493 DSFDIEVGTSP 503 + P Sbjct: 389 PVLRTDPAKPP 399 >6F0B-A nrPDB Length = 395 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 47/141 (33%), Gaps = 24/141 (17%) Query: 352 IRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPV-TAQYGRAKKDLVIESHDAAFKV 410 + ++ + E++ L V E LR+ A +D+ + V Sbjct: 247 VSYALQPEKFSVVHEHPERIPLL---VEELLRYHTVSQLGLGRIATEDVEV----GGVTV 299 Query: 411 KAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQ 470 +AG+M+ PLA RD +F DE +R G Q Sbjct: 300 RAGQMVVAALPLANRDESVFPNPDELDFDRPSVPH----------------VGFGYGPHQ 343 Query: 471 CAGKDFVVLVARLFVIEIFRR 491 C G+ + + + + RR Sbjct: 344 CVGQALARVELQEAIPAVIRR 364 >5XJN-A nrPDB Length = 455 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 52/145 (35%), Gaps = 20/145 (13%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 +E +L + V E LR+ + +A KD I +K G+ + A RD Sbjct: 319 LENPKLIPAAVDEVLRYSGSIVGWRRKALKDTEI----GGVAIKEGDGVLLLMGSANRDE 374 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 F+ +EF R +N E + G C G L A++ + E Sbjct: 375 ARFENGEEFDISR---------------ANAREHLSFGFGIHYCLGNMLAKLQAKICLEE 419 Query: 488 IFRRYDSFDIEVGTSPLGSSVNFSS 512 + R S + V +G N S Sbjct: 420 VTRLVPSLHL-VADKAIGFRENLSF 443 >5GWE-A nrPDB Length = 405 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 52/145 (35%), Gaps = 20/145 (13%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 +E +L + V E LR+ + +A KD I +K G+ + A RD Sbjct: 269 LENPKLIPAAVDEVLRYSGSIVGWRRKALKDTEI----GGVAIKEGDGVLLLMGSANRDE 324 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 F+ +EF R +N E + G C G L A++ + E Sbjct: 325 ARFENGEEFDISR---------------ANAREHLSFGFGIHYCLGNMLAKLQAKICLEE 369 Query: 488 IFRRYDSFDIEVGTSPLGSSVNFSS 512 + R S + V +G N S Sbjct: 370 VTRLVPSLHL-VADKAIGFRENLSF 393 >4YZR-A nrPDB Length = 405 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 28/140 (20%), Positives = 49/140 (35%), Gaps = 23/140 (16%) Query: 369 EKMELTKSVVYECLRFEPPVTAQ-YGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 ++ E+ + V E LR+ PV A +D + H +K G+M++ A RDP Sbjct: 269 QQPEMIATAVEELLRYTSPVVMMANRWAIEDFTYKGH----SIKRGDMIFIGIGSANRDP 324 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 F+ + R + + G C G L + Sbjct: 325 NFFENPEILNINR----------------SPNRHISFGFGIHFCLGAPLARLEGHIAFKA 368 Query: 488 IFRRYDSFDIEVGTSPLGSS 507 + +R+ DIE+ +P Sbjct: 369 LLKRFP--DIELAVAPDDIQ 386 >5DQN-A nrPDB Length = 426 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 46/141 (32%), Gaps = 21/141 (14%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 + K E ++ E +R+ PV+A A +D+ + ++K G+ + A D Sbjct: 276 LYKKERPETAADEIVRWATPVSAFQRTALEDVEL----GGVQIKKGQRVVMSYRSANFDE 331 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 ++F+ F R S P G C G + + L Sbjct: 332 EVFEDPHTFNILR---------------SPNPHVGFGGTGAHYCIGANLARMTINLIFNA 376 Query: 488 IFRRYDSFDIEVGTSPLGSSV 508 I D++ +P Sbjct: 377 IADNMP--DLKPIGAPERLKS 395 >5IT1-A nrPDB Length = 399 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 23/153 (15%), Positives = 47/153 (30%), Gaps = 20/153 (13%) Query: 361 GELTMGAIEKME-LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGY 419 + ++K L + V E LR+ +T A++ + ++ GE + + Sbjct: 256 RPDQLALLQKDPSLIGNAVEELLRY---LTIGQFGAERVATQDGEIGGVRIAKGEQVVTH 312 Query: 420 QPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVL 479 A DP + + F R G QC G+ + Sbjct: 313 LLSADFDPAFVEDPERFDITR----------------RPAPHLAFGFGAHQCIGQQLARI 356 Query: 480 VARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSS 512 ++ +FRR+ + + L + Sbjct: 357 ELQIVFGTLFRRFPTLRLAKPVEELRFRNDMVF 389 >2FR7-A nrPDB Length = 412 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 44/127 (34%), Gaps = 20/127 (15%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 L ++ E +RFE PV + +D+ + A + GE + + A RDP+ + Sbjct: 281 PSLARNAFEEAVRFESPVQTFFRTTTRDVEL----AGATIGEGEKVLMFLGSANRDPRRW 336 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 D D + R G C G+ L + + + R Sbjct: 337 DDPDRYDITRKTSGH----------------VGFGSGVHMCVGQLVARLEGEVVLAALAR 380 Query: 491 RYDSFDI 497 + + +I Sbjct: 381 KVAAIEI 387 >1EHE-A nrPDB Length = 403 Score = 62.4 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 51/146 (34%), Gaps = 23/146 (15%) Query: 371 MELTKSVVYECLRFEPP-VTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 L V E R+ A AK+D++I V+A E + A RD ++ Sbjct: 269 PSLAPQFVEELCRYHTASALAIKRTAKEDVMIGDKL----VRANEGIIASNQSANRDEEV 324 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 F+ DEF R + G+ +C + ++ Sbjct: 325 FENPDEFNMNRKWPPQDPL--------------GFGFGDHRCIAEHLAKAELTTVFSTLY 370 Query: 490 RRYDSFDIEVGTSPLGSSVNFSSLRK 515 +++ + V PLG +N++ L + Sbjct: 371 QKFPDLKVAV---PLG-KINYTPLNR 392 >3B98-A nrPDB Length = 475 Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 60/159 (37%), Gaps = 14/159 (8%) Query: 342 HQVHNR-LAEEIRSVIKSNGGELTMGAIEK-MELTKSVVYECLRFEPPVTAQYGRAKKDL 399 H R + EEI G L + +K + SV++E LR + Sbjct: 283 HPEALRAVREEI-----QGGKHLRLEERQKNTPVFDSVLWETLRLTAAALITRDVTQDKK 337 Query: 400 VIESHDAAFKVKAGEML-YGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNG 458 + S+ + ++ G+ L DP+I + + F +RF+ ++ + + NG Sbjct: 338 ICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFL--NADRTEKKDFFKNG 395 Query: 459 PETETP----TVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 + P + C G+ F V + V I R+D Sbjct: 396 ARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFD 434 >5VWS-A nrPDB Length = 393 Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 34/132 (25%), Gaps = 21/132 (15%) Query: 362 ELTMGAIEKME-LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQ 420 A+ L + + E LR P +D+ I + A + + Sbjct: 253 PEAEKAVRADPSLIPAALEESLRLRSPFLQAGRVTTRDVTIAGE----TIPANRFVMAWI 308 Query: 421 PLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLV 480 A D + F + F R G C G L Sbjct: 309 LSANHDDRRFPDPERFDLHRQTTGHIA----------------FGHGVHFCLGAQLGRLE 352 Query: 481 ARLFVIEIFRRY 492 R+ + + R+ Sbjct: 353 GRIALERLLGRF 364 >4TRI-A nrPDB Length = 407 Score = 61.6 bits (148), Expect = 7e-10, Method: Composition-based stats. Identities = 30/165 (18%), Positives = 54/165 (32%), Gaps = 23/165 (13%) Query: 327 KILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEP 386 +I+F ++ IG + L+ +++ + + ++L + E LR+ Sbjct: 222 EIVFETLLILIG-GDETTRHTLSGGTEQLLRH--RDQWDALVADVDLLPGAIEEMLRWTS 278 Query: 387 PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEG 446 PV L ++ +++AGE + A D +F D F +R Sbjct: 279 PVKNMCRT----LTADTVFHGTELRAGEKIMLMFESANFDESVFGDPDNFRIDR------ 328 Query: 447 EKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 N G C G L RL + RR Sbjct: 329 ----------NPNSHVAFGFGTHFCLGNQLARLELRLMTERVLRR 363 >6GMF-A nrPDB Length = 397 Score = 61.6 bits (148), Expect = 8e-10, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 64/200 (32%), Gaps = 55/200 (27%) Query: 292 SAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEE 351 +AGE+L A+ L I+ E T +L+ N + + H Sbjct: 219 TAGEVLSFANTLLIAGNETTTSLI---------------GNAL--VALTDHPEQ------ 255 Query: 352 IRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVK 411 + + +L+ L +VV E LR+E P + + D+ I ++ Sbjct: 256 ----LAAAQADLS--------LVPAVVEEVLRYESPAQCIFRQTMTDVEIGDE----RIP 299 Query: 412 AGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQC 471 A ++ A RD F D F R H+ + C Sbjct: 300 ARSVVLPLLASANRDESRFPDPDRFDIHR-------DTKGHLAFGLD---------IHFC 343 Query: 472 AGKDFVVLVARLFVIEIFRR 491 G L A++ + + R Sbjct: 344 IGAPLARLEAKVMLEVLLAR 363 >3A1L-A nrPDB Length = 425 Score = 61.3 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 51/151 (33%), Gaps = 23/151 (15%) Query: 340 AGHQVHNR-LAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKD 398 AGH+ LA+ + ++ ++ E T + V E +R++PPV A A +D Sbjct: 254 AGHETTTNFLAKAVLTLR--AHRDVLDELRTTPESTPAAVEELMRYDPPVQAVTRWAYED 311 Query: 399 LVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNG 458 + + HD + G + A RDP F D R + Sbjct: 312 IRLGDHD----IPRGSRVVALLGSANRDPARFPDPDVLDVHRAAERQ------------- 354 Query: 459 PETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 +G C G A + + + Sbjct: 355 ---VGFGLGIHYCLGATLARAEAEIGLRALL 382 >6FYJ-A nrPDB Length = 421 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 45/127 (35%), Gaps = 20/127 (15%) Query: 372 ELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 + ++ V E RF P KKD +K + G + DP+I+ Sbjct: 278 KYSQMFVQEVRRFYPFFPFVVALVKKDFT----WKGYKFEEGTLTLLDLYGTNHDPEIWK 333 Query: 432 RADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVG-----NKQCAGKDFVVLVARLFVI 486 D F P+RF W P + P G +CAG+ + V ++ + Sbjct: 334 NPDVFSPDRFAK-----------WEGSPFSFIPQGGGDYFMGHRCAGEWVTIEVMKVSLD 382 Query: 487 EIFRRYD 493 + R D Sbjct: 383 YLTNRMD 389 >2UUQ-A nrPDB Length = 414 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 42/143 (29%), Gaps = 24/143 (16%) Query: 356 IKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEM 415 + + L + E V E LR PV +D+ I + AG Sbjct: 268 RRPDQRRLLLDD---PEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDT----TIPAGRR 320 Query: 416 LYGYQPLATRDPKIF-DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGK 474 + A RD + + A E R T + G C G Sbjct: 321 VLLLYGSANRDERQYGPDAAELDVTR----------------CPRNILTFSHGAHHCLGA 364 Query: 475 DFVVLVARLFVIEIFRRYDSFDI 497 + R+ + E+ R F++ Sbjct: 365 AAARMQCRVALTELLARCPDFEV 387 >6BLD-A nrPDB Length = 419 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 26/137 (18%), Positives = 39/137 (28%), Gaps = 22/137 (16%) Query: 374 TKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 + V E +R+ PV A D + ++AGE + + D F Sbjct: 294 IGTAVEELVRWATPVMTFRRTAAADFELGGQL----IRAGEKVVMFYASGNWDEDAFCHP 349 Query: 434 DEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 + R S P G C G R E+ + Sbjct: 350 ERLDLSR---------------SPNPHVGFGGGGVHFCLGAHLARAQLRAIFGELLVQLP 394 Query: 494 SFDIEVGTSPLGSSVNF 510 DI+ G P+ NF Sbjct: 395 --DIQAGD-PVYVPGNF 408 >3ABB-A nrPDB Length = 408 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 44/132 (33%), Gaps = 20/132 (15%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 + VV E LRF AK+D+ + +KAG+ + L RD Sbjct: 270 LRDPGAVSGVVEELLRFTSVSDHIVRMAKEDIEV----GGATIKAGDAVLVSITLMNRDA 325 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 K ++ D F R HV + G QC G++ + + Sbjct: 326 KAYENPDIFDARR-------NARHHVGF---------GHGIHQCLGQNLARAELEIALGG 369 Query: 488 IFRRYDSFDIEV 499 +F R + V Sbjct: 370 LFARIPGLRLAV 381 >5XW2-A nrPDB Length = 419 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 46/134 (34%), Gaps = 26/134 (19%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L ++ E +RF PV A Y +D+ + ++ A +M+ + A RD + F Sbjct: 288 LIPGLLEESMRFLSPVAATYRATTRDVEVAGQ----RLSADQMVMVWFGAANRDARQFAE 343 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETET-PTVGNKQCAGKDFVVLVARLFVIEIFRR 491 + F R GP G C G + R+ + + R Sbjct: 344 PELFDMTR-----------------GPNPHLGFGRGIHFCLGGPLARMEGRVALDHLLDR 386 Query: 492 YDSFDIEVGTSPLG 505 + E+ T P Sbjct: 387 FP----ELYTDPER 396 >6DCD-A nrPDB Length = 424 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 19/119 (15%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L + + E LR + PV + A+K + + AG ++ A RDP+ F+ Sbjct: 284 LIPNFIEESLRMDSPVKSDSRLARKRTTV----GGLDIAAGTVVMVLPGAANRDPRRFED 339 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 EF +R + H+ ++ G C G + R+ + I R Sbjct: 340 PHEFRLDR------PNVREHMAFAR---------GVHSCPGGPLARVEGRVSLERILDR 383 >1Z8P-A nrPDB Length = 404 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 38/129 (29%), Gaps = 20/129 (15%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 + V E LR+ P A +++ I + + A RDPK Sbjct: 269 RDPSALPNAVEEILRYIAPPETTTRFAAEEVEI----GGVAIPQYSTVLVANGAANRDPK 324 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 F F R H+ + G C G+ L + + + Sbjct: 325 QFPDPHRFDVTR-------DTRGHLSF---------GQGIHFCMGRPLAKLEGEVALRAL 368 Query: 489 FRRYDSFDI 497 F R+ + + Sbjct: 369 FGRFPALSL 377 >3TYW-A nrPDB Length = 417 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 44/141 (31%), Gaps = 21/141 (14%) Query: 352 IRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQ-YGRAKKDLVIESHDAAFKV 410 + +++ + EL + +L + V E LR + A +D+ + V Sbjct: 260 LSTLLLLDRPELPAELRKDPDLMPAAVDELLRVLSVADSIPLRVAAEDIELSGR----TV 315 Query: 411 KAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQ 470 A + + A DP+ FD + R G Q Sbjct: 316 PADDGVIALLAGANHDPEQFDDPERVDFHR----------------TDNHHVAFGYGVHQ 359 Query: 471 CAGKDFVVLVARLFVIEIFRR 491 C G+ L + + + RR Sbjct: 360 CVGQHLARLELEVALETLLRR 380 >2XKR-A nrPDB Length = 398 Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 41/148 (27%), Gaps = 22/148 (14%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 L + E LR+ PV L ++ + AGE + A D Sbjct: 258 RDPSLLPGAIEEMLRWTAPVKNMCRV----LTADTEFHGTALCAGEKMMLLFESANFDEA 313 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 +F ++F +R N G C G L L + Sbjct: 314 VFCEPEKFDVQR----------------NPNSHLAFGFGTHFCLGNQLARLELSLMTERV 357 Query: 489 FRRYDSFDIEVGTS--PLGSSVNFSSLR 514 RR + S PL + S L Sbjct: 358 LRRLPDLRLVADDSVLPLRPANFVSGLE 385 >2ZQJ-A nrPDB Length = 417 Score = 59.7 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 44/119 (36%), Gaps = 10/119 (8%) Query: 375 KSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRAD 434 + V E R+ P KKD V + + K G + DP+++D D Sbjct: 277 EMFVQEVRRYYPFGPFLGALVKKDFVWNN----CEFKKGTSVLLDLYGTNHDPRLWDHPD 332 Query: 435 EFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 EF PERF E L+ P+ +C G+ + V + + + + + Sbjct: 333 EFRPERFAEREE------NLFDMIPQGGGHAEKGHRCPGEGITIEVMKASLDFLVHQIE 385 >4DO1-A nrPDB Length = 410 Score = 59.7 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 43/128 (33%), Gaps = 20/128 (15%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 L ++ E +RFE PV + +++ + + GE + + A RDP+ + Sbjct: 279 PTLARNAFEEAVRFESPVQTFFRTTTREVEL----GGAVIGEGEKVLMFLGSANRDPRRW 334 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 D + R G C G+ L + + + R Sbjct: 335 SDPDLYDITRKTSGH----------------VGFGSGVHMCVGQLVARLEGEVMLSALAR 378 Query: 491 RYDSFDIE 498 + + DI+ Sbjct: 379 KVAAIDID 386 >3ABA-A nrPDB Length = 403 Score = 59.3 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 41/145 (28%), Gaps = 21/145 (14%) Query: 369 EKMELTKSVVYECLRFEPPVTAQ-YGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 E L + V E LR+ A +D+ + ++ GE + + A DP Sbjct: 265 EDPSLVGNAVEELLRYLTIGQFGGERVATRDVEL----GGVRIAKGEQVVAHVLAADFDP 320 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 + + F R G QC G+ + ++ Sbjct: 321 AFVEEPERFDITR----------------RPAPHLAFGFGAHQCIGQQLARIELQIVFET 364 Query: 488 IFRRYDSFDIEVGTSPLGSSVNFSS 512 +FRR + L + Sbjct: 365 LFRRLPGLRLAKPVEELRFRHDMVF 389 >2Y5N-A nrPDB Length = 417 Score = 59.3 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 49/146 (33%), Gaps = 22/146 (15%) Query: 362 ELTMGAIEKMELTKSVVYECLRFEP--PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGY 419 EL +++ EL S V E R+ P TA A +D+ + ++AGE + Sbjct: 275 ELRRQLLDRPELIPSAVEELTRWVPLGVGTAFPRYAVEDVTLRG----VTIRAGEPVLAS 330 Query: 420 QPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVL 479 A RD F AD +R + G C G + Sbjct: 331 TGAANRDQAQFPDADRIDVDR----------------TPNQHLGFGHGVHHCLGAPLARV 374 Query: 480 VARLFVIEIFRRYDSFDIEVGTSPLG 505 ++ + + +R + + + L Sbjct: 375 ELQVALEVLLQRLPGIRLGIPETQLR 400 >1LG9-A nrPDB Length = 398 Score = 58.9 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 40/121 (33%), Gaps = 21/121 (17%) Query: 378 VYECLRFEP-PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEF 436 V E +R+ P + A++DL + ++K G+ + P A RDP + D Sbjct: 273 VDELIRYLTVPYSPTPRIAREDLTLAGQ----EIKKGDSVICSLPAANRDPALAPDVDRL 328 Query: 437 VPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFD 496 R G C G L R E++RR+ + Sbjct: 329 DVTR----------------EPIPHVAFGHGVHHCLGAALARLELRTVFTELWRRFPALR 372 Query: 497 I 497 + Sbjct: 373 L 373 >2Z36-A nrPDB Length = 413 Score = 58.6 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 51/164 (31%), Gaps = 39/164 (23%) Query: 337 IGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPV-TAQYGRA 395 +G H E +V+K+N G T V E LR+ A Sbjct: 259 VGLLSHP-------EQLTVVKANPGR-----------TPMAVEELLRYFTIADGVTSRLA 300 Query: 396 KKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLW 455 +D+ I +KAGE + A DP +F ER Sbjct: 301 TEDVEI----GGVSIKAGEGVIVSMLSANWDPAVFKDPAVLDVER--------------- 341 Query: 456 SNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEV 499 G QC G++ + ++ +FRR S + V Sbjct: 342 -GARHHLAFGFGPHQCLGQNLARMELQIVFDTLFRRIPSLRLAV 384 >2NZA-A nrPDB Length = 413 Score = 58.6 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 29/163 (17%), Positives = 47/163 (28%), Gaps = 28/163 (17%) Query: 342 HQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRF--EPPVTAQYGRAKKDL 399 H V L + EL E+ + + E LR+ A +D+ Sbjct: 251 HNVGQML------YLLLTRRELMARMRERPGARGTALDELLRWISHRTSVGLARIALEDV 304 Query: 400 VIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 + ++ AGE +Y A RDP +F D +R + Sbjct: 305 EVHGT----RIAAGEPVYVSYLAANRDPDVFPDPDRIDLDR----------------DPN 344 Query: 460 ETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTS 502 G+ C G + L V + R + V Sbjct: 345 PHLAYGNGHHFCTGAVLARMQTELLVDTLLERLPGLRLAVPAE 387 >1ODO-A nrPDB Length = 408 Score = 58.6 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 30/139 (21%), Positives = 43/139 (30%), Gaps = 21/139 (15%) Query: 361 GELTMGAIEKMELT-KSVVYECLRFEPPVTAQ-YGRAKKDLVIESHDAAFKVKAGEMLYG 418 + + K E+T VV E LR EP V A D+ + + GE + Sbjct: 261 RPDQLALVRKGEVTWADVVEETLRHEPAVKHLPLRYAVTDIALPD---GRTIARGEPILA 317 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVV 478 A R P + AD F R V E G C G Sbjct: 318 SYAAANRHPDWHEDADTFDATRTVKEHLA----------------FGHGVHFCLGAPLAR 361 Query: 479 LVARLFVIEIFRRYDSFDI 497 + L + +F R+ + Sbjct: 362 MEVTLALESLFGRFPDLRL 380 >4YT3-A nrPDB Length = 410 Score = 58.6 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 54/161 (33%), Gaps = 25/161 (15%) Query: 359 NGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 + E+ E ++L V E LRF + K+D + ++K G+ + Sbjct: 262 DDKEVYQELHENLDLVPQAVEEMLRFRFNLIKLDRTVKED----NDLLGVELKEGDSVVV 317 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVV 478 + A D ++F+ R N + T G C G Sbjct: 318 WMSAANMDEEMFEDPFTLNIHR---------------PNNKKHLTFGNGPHFCLGAPLAR 362 Query: 479 LVARLFVIEIFRRYD------SFDIEVGTSPLGSSVNFSSL 513 L A++ + +++ SF +E + + +SL Sbjct: 363 LEAKIALTAFLKKFKHIEAVPSFQLEENLTDSATGQTLTSL 403 >4FB2-A nrPDB Length = 398 Score = 58.2 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 50/137 (36%), Gaps = 21/137 (15%) Query: 362 ELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQP 421 EL I EL + V E LRF P +++ + +K G+ + P Sbjct: 253 ELRRRLIAHPELIPNAVDELLRFYGPAMV-GRLVTQEVTVGD----ITMKPGQTAMLWFP 307 Query: 422 LATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVA 481 +A+RD FD D V ER + G +C G + + A Sbjct: 308 IASRDRSAFDSPDNIVIER----------------TPNRHLSLGHGIHRCLGAHLIRVEA 351 Query: 482 RLFVIEIFRRYDSFDIE 498 R+ + E +R F ++ Sbjct: 352 RVAITEFLKRIPEFSLD 368 >5LIV-A nrPDB Length = 450 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 18/143 (12%), Positives = 42/143 (29%), Gaps = 20/143 (13%) Query: 362 ELTMGAIEKME-LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQ 420 T+ + + L + + E +R+ P ++D+ ++ + AG ++ Sbjct: 299 PDTLARVRQDPSLLPAAIEEGMRWCPSSFGVLRMVERDVRLDDQ----ALSAGTVVCLAG 354 Query: 421 PLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLV 480 D + + + +R P G C G + Sbjct: 355 IAGNYDETAYPSPEVYDIDR---------------KPLPAANVFGGGAHFCVGAPLARME 399 Query: 481 ARLFVIEIFRRYDSFDIEVGTSP 503 AR+ + + R+ P Sbjct: 400 ARVGLQALLARFPGLRAVPEERP 422 >2RFC-A nrPDB Length = 343 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 42/127 (33%), Gaps = 20/127 (15%) Query: 378 VYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFV 437 V E LR+ P+ R + +S+ K+K G+ + Y A RD FD D F Sbjct: 222 VEETLRYYSPIQFLPHRFAAE---DSYINNKKIKKGDQVIVYLGSANRDETFFDEPDLFK 278 Query: 438 PERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDI 497 R +G C G L A + + +I + I Sbjct: 279 IGR-----------------REMHLAFGIGIHMCLGAPLARLEASIALNDILNHFKRIKI 321 Query: 498 EVGTSPL 504 + S L Sbjct: 322 DYKKSRL 328 >5D3U-A nrPDB Length = 427 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 50/141 (35%), Gaps = 20/141 (14%) Query: 374 TKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 + E LR+ + A KD+ + +++AG+ L + A RD +F+R Sbjct: 300 VDNTANEVLRYNASNQFTWRVAAKDVEM----GGVRIEAGQTLALFLGSANRDANMFERP 355 Query: 434 DEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 ++F +R N + G C + L + F + + R+ Sbjct: 356 NDFDLDR---------------PNSARHLSFGQGVHACLAAQLISLQLKWFYVALLNRFP 400 Query: 494 SFDIEVGTSPLGSSVNFSSLR 514 G ++ F SLR Sbjct: 401 GIRT-AGEPIWNENLEFRSLR 420 >5HIW-A nrPDB Length = 398 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 39/135 (28%), Gaps = 20/135 (14%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 ++ L + E R+ +++ I + AG +LY D + Sbjct: 256 QQPSLLPQAIEESTRWCSSAAGIVRFVEREATIGGE----TLAAGTILYLSLIARHYDEE 311 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 I+ R + F R G C G + AR+ V + Sbjct: 312 IYPRPETFDIHR----------------RPVGMLNFGGGLHYCVGAPLARMEARVGVSLL 355 Query: 489 FRRYDSFDIEVGTSP 503 R+ + + P Sbjct: 356 LERFPALRADPTVQP 370 >4MM0-A nrPDB Length = 399 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 53/173 (30%), Gaps = 23/173 (13%) Query: 342 HQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPV-TAQYGRAKKDLV 400 N+L + ++++ L S V E +R+ P A + +D+ Sbjct: 239 EPASNQLGSSVLTLLRFPDR--LAELRRDPGLLPSAVEELMRYAPAGDGALFRVTLEDVT 296 Query: 401 IESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPE 460 I + A + A DP+ FD +R + L H Sbjct: 297 IGDT----HIPANSAVLASTQAANWDPRRFDDPTGLRLDR--PDNQHTALGH-------- 342 Query: 461 TETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSL 513 G C G + ++ + + RR+ + S L S S L Sbjct: 343 ------GIHFCLGAALARVELQVAIGALLRRFPRLALATDESGLRWSSPGSML 389 >5HDI-A nrPDB Length = 404 Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 42/121 (34%), Gaps = 19/121 (15%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 EL + + E LR+EPP Y + ++ ++ A L A RDP F Sbjct: 274 PELLGAFIEETLRYEPPFRGHYRHVRNATTLDGT----ELPADSHLLLLWGAANRDPAQF 329 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 + EF +R G+ + G C G L AR+ + + Sbjct: 330 EAPGEFRLDRAGGKGH---------------ISFGKGAHFCVGAALARLEARIVLRLLLD 374 Query: 491 R 491 R Sbjct: 375 R 375 >6F88-A nrPDB Length = 400 Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 18/143 (12%), Positives = 42/143 (29%), Gaps = 20/143 (13%) Query: 362 ELTMGAIEKME-LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQ 420 T+ + + L + + E +R+ P ++D+ ++ + AG ++ Sbjct: 249 PDTLARVRQDPSLLPAAIEEGMRWCPSNFGVLRMVERDVRLDDQ----ALSAGTVVCLAG 304 Query: 421 PLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLV 480 D + + + +R P G C G + Sbjct: 305 IAGNYDETAYPSPEVYDIDR---------------KPLPAANVFGGGAHFCVGAPLARME 349 Query: 481 ARLFVIEIFRRYDSFDIEVGTSP 503 AR+ + + R+ P Sbjct: 350 ARVGLQALLARFPGLRAVPEERP 372 >6GK6-A nrPDB Length = 411 Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 32/135 (23%), Positives = 45/135 (33%), Gaps = 23/135 (17%) Query: 369 EKMELTKSVVYECLRFE-PPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 E L S V E LR E P + + +D+ + +V AGE + A RDP Sbjct: 271 EDPGLVGSAVEEALRCEGPAELSTIRWSLEDIEL----FGARVPAGEGVAAGLLAANRDP 326 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 + F D F R + G C G + A + Sbjct: 327 QHFPDPDRFDIGR----------------SPNRHIGFGGGIHFCLGAMLARIEAAIAFST 370 Query: 488 IFRRYDSFDIEVGTS 502 + RR IE+ TS Sbjct: 371 LLRRLP--RIELATS 383 >5EX6-C nrPDB Length = 434 Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 43/138 (31%), Gaps = 24/138 (17%) Query: 371 MELTKSVVYECLRFEP-PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 + + V E +R+ P A +D + +KAGE + P A RDP + Sbjct: 302 VPAAERAVDELIRYLTVPYAPTPRTAIEDSTVGDQV----IKAGETVLCSLPTANRDPAL 357 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 AD R G C G L R+ ++ Sbjct: 358 LPDADRLDVTREAVPHVA----------------FGHGVHHCLGAALARLELRIAYTALW 401 Query: 490 RRYDSFDIEVGTSPLGSS 507 RR+ + P G++ Sbjct: 402 RRFPDLRL---ADPDGAT 416 >3BUJ-A nrPDB Length = 397 Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 51/138 (36%), Gaps = 22/138 (15%) Query: 345 HNRLAEEIRSVIKSNGGELTMGAI--EKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIE 402 H +A ++ + + S + + +L V ECLR++P V + L ++ Sbjct: 235 HETVASQVGNAVLSLLAHPDQLDLLRRRPDLLAQAVEECLRYDPSVQSNTR----QLDVD 290 Query: 403 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 +++ +++ A RDP+ +DR D+F ER + + Sbjct: 291 VELRGRRLRRDDVVVVLAGAANRDPRRYDRPDDFDIER----------------DPVPSM 334 Query: 463 TPTVGNKQCAGKDFVVLV 480 + G + C G Sbjct: 335 SFGAGMRYCLGSYLARTQ 352 >5YHJ-A nrPDB Length = 413 Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 34/120 (28%), Gaps = 20/120 (16%) Query: 378 VYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFV 437 V E RF P R K D + + G + D I+ D F Sbjct: 276 VQEVRRFYPFFPVAAARVKTDFEWDG----YAFPEGTLTLLDLYGTNHDVSIWTEPDRFD 331 Query: 438 PERFVGEEGEKLLRHVLWSNGPETETPTVG-----NKQCAGKDFVVLVARLFVIEIFRRY 492 P RF W P P G +CAG+ + + + + Y Sbjct: 332 PSRFKD-----------WKESPFNFIPQGGGDVDFGHRCAGEHVTIAILAQVIELFTKEY 380 >5Y1I-A nrPDB Length = 403 Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 52/157 (33%), Gaps = 21/157 (13%) Query: 337 IGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVT-AQYGRA 395 +G N +A +++++ + + ++ + V E LR+ A Sbjct: 235 LGAGHETTANMIALGTLALLENPEQLAEVRDSDDPKVIVNTVEELLRYLTIAQDTVRRIA 294 Query: 396 KKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR-ADEFVPERFVGEEGEKLLRHVL 454 +D+ I +KAGE + A DP ++ D R RH+ Sbjct: 295 AEDIEI----GGVVIKAGEGIVFPLNAANWDPDLYPEAPDRLDIHR------ANARRHLA 344 Query: 455 WSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 + G QC G + ++ + RR Sbjct: 345 F---------GYGVHQCLGATLARVELQIVYSTLLRR 372 >5Z9I-A nrPDB Length = 398 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 20/136 (14%), Positives = 44/136 (32%), Gaps = 20/136 (14%) Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 L +++ E +R+ P+ ++ + A + ++L + A RD + F++ Sbjct: 269 LVPALLEESMRYMSPICGVGRATNSEVEV----AGTVIPKDQLLLVWTGAANRDERQFEK 324 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 D F R + G C G+ + ++ V + R Sbjct: 325 PDVFDAGR----------------SPNAHLGFGRGIHFCLGRQLARMESKAAVEILLDRL 368 Query: 493 DSFDIEVGTSPLGSSV 508 + + P V Sbjct: 369 PTLRADPANPPTFLQV 384 >6A7I-A nrPDB Length = 411 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 41/133 (30%), Gaps = 22/133 (16%) Query: 375 KSVVYECLRFEPPVT-AQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF-DR 432 V+ E LR+ P + A +D+ + + GE L RD + + Sbjct: 274 DGVIEETLRWNTPTSHVLIRFATEDIEVGDKI----LPKGEGLIISFGALGRDEEQYGPT 329 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 A EF R G C G L A + + ++ R+ Sbjct: 330 AGEFDATR----------------TPNRHIAFGHGPHVCPGAALSRLEAGIALPALYERF 373 Query: 493 DSFDIEVGTSPLG 505 D+ V S L Sbjct: 374 PELDLAVPASDLR 386 >5CJE-A nrPDB Length = 393 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 37/122 (30%), Gaps = 21/122 (17%) Query: 371 MELTKSVVYECLRFEPPV-TAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 M L V E LRFE PV TA Y A + + I + G+ + A RDP Sbjct: 263 MTLLDGAVEEVLRFEGPVETATYRYAAESMEI----GGTAIAEGDPVMIGLDAAGRDPAR 318 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 F R G C G L AR+ + + Sbjct: 319 HPDPHVFDIHR----------------APQGHLAFGHGIHYCLGAPLARLEARVALRSLL 362 Query: 490 RR 491 R Sbjct: 363 ER 364 >1UED-A nrPDB Length = 406 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 45/143 (31%), Gaps = 21/143 (14%) Query: 369 EKMELTKSVVYECLR-FEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 E E + VV E +R P A KD+VI+ +KAG+ + +A RD Sbjct: 273 ESPEKAERVVNELVRYLSPVQAPNPRLAIKDVVIDGQL----IKAGDYVLCSILMANRDE 328 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 + D R + G C G + R+ Sbjct: 329 ALTPDPDVLDANRAAVSD----------------VGFGHGIHYCVGAALARSMLRMAYQT 372 Query: 488 IFRRYDSFDIEVGTSPLGSSVNF 510 ++RR+ + V + F Sbjct: 373 LWRRFPGLRLAVPIEEVKYRSAF 395 >1GWI-A nrPDB Length = 411 Score = 55.9 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 52/157 (33%), Gaps = 32/157 (20%) Query: 351 EIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVT-AQYGRAKKDLVIESHDAAFK 409 E R+++ S E + +VV E LRF P + A +D+ + Sbjct: 263 EQRALVLSGEAEWS-----------AVVEETLRFSTPTSHVLIRFAAEDVPVGDRV---- 307 Query: 410 VKAGEMLYGYQPLATRDPKIF-DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGN 468 + AG+ L RD + AD F R G + G Sbjct: 308 IPAGDALIVSYGALGRDERAHGPTADRFDLTRTSGNRH---------------ISFGHGP 352 Query: 469 KQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLG 505 C G + A + + ++ R+ D+ V + L Sbjct: 353 HVCPGAALSRMEAGVALPALYARFPHLDLAVPAAELR 389 >1Q5D-A nrPDB Length = 419 Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 33/152 (21%), Positives = 56/152 (36%), Gaps = 24/152 (15%) Query: 354 SVIKSNGGELTMGAIEKME-LTKSVVYECLRFEPPV-TAQYGRAKKDLVIESHDAAFKVK 411 +V+ + ++ L ++ + E LRF+ + A++DL +K Sbjct: 266 AVLNLLRSPEALELVKAEPGLMRNALDEVLRFDNILRIGTVRFARQDLE----YCGASIK 321 Query: 412 AGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQC 471 GEM++ P A RD +F R D F R + + G C Sbjct: 322 KGEMVFLLIPSALRDGTVFSRPDVFDVRR----------------DTSASLAYGRGPHVC 365 Query: 472 AGKDFVVLVARLFVIEIFRRYDSFDIEVGTSP 503 G L A + V IFRR+ ++ +P Sbjct: 366 PGVSLARLEAEIAVGTIFRRFPEMKLK--ETP 395 >2VZM-A nrPDB Length = 436 Score = 55.1 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 43/130 (33%), Gaps = 21/130 (16%) Query: 371 MELTKSVVYECLRFEPPV-TAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 M L V E LR+E PV +A Y + + ++ + AG+ + A R P+ Sbjct: 293 MTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTV----IPAGDTVLVVLADAHRTPER 348 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 F F R + G C G L AR+ V + Sbjct: 349 FPDPHRFDIRR----------------DTAGHLAFGHGIHFCIGAPLARLEARIAVRALL 392 Query: 490 RRYDSFDIEV 499 R ++V Sbjct: 393 ERCPDLALDV 402 >3OFT-A nrPDB Length = 396 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 46/151 (30%), Gaps = 37/151 (24%) Query: 339 RAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKD 398 A H RL E + +L + E +R P V A D Sbjct: 250 LARHPEDQRLLRE------------------RPDLIPAAADELMRRYPTVAV-SRNAVAD 290 Query: 399 LVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNG 458 + + ++ G+++Y L DP F+ +E +R + Sbjct: 291 VDADG----VTIRKGDLVYLPSVLHNLDPASFEAPEEVRFDRGLAPIRHT---------- 336 Query: 459 PETETPTVGNKQCAGKDFVVLVARLFVIEIF 489 T VG +C G + +F+ E Sbjct: 337 ----TMGVGAHRCVGAGLARMEVIVFLREWL 363 >4XE3-A nrPDB Length = 407 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 52/251 (20%), Positives = 90/251 (35%), Gaps = 38/251 (15%) Query: 253 PLLSIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATH 312 PL L R + ++ + L A ++ Q +F + G + R+ T Sbjct: 164 PLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQ---DFMVYMDGLVAQR-------RDAPTE 213 Query: 313 NLLFATCFNTWGG---MKILFPNMVKRIGRAGHQVH-NRLAEEIRSVIKSNGGELTMGAI 368 +LL A T K NM + AGH+ N++ + ++ ++ + Sbjct: 214 DLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESL--V 271 Query: 369 EKMELTKSVVYECLRFEPPVTA--QYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRD 426 L + V E LR+ P V+A A +D+ + + V+AGE + A RD Sbjct: 272 ADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVEL----STVTVRAGEPCVVHFASANRD 327 Query: 427 PKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVI 486 ++FD ADE R G C G L + + Sbjct: 328 EEVFDHADELDFHRERNPHIA----------------FGHGAHHCIGAQLGRLELQEALS 371 Query: 487 EIFRRYDSFDI 497 + RR+ + D+ Sbjct: 372 ALVRRFPTLDL 382 >5NWS-A nrPDB Length = 435 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 58/177 (32%), Gaps = 20/177 (11%) Query: 333 MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKME-LTKSVVYECLRFEPPV-TA 390 M+ + AGH+ L + + ++ G+ + + K L V+E +R+ V A Sbjct: 260 MILTLVLAGHETSAHLIGNGTAALLTHPGQWAL--LRKDPALLPRAVHELMRWCGSVHVA 317 Query: 391 QYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLL 450 + A +DL + A V G+ + A DP+ + D R + E + Sbjct: 318 RLRYATEDLEL----AGTPVARGDAVQLVLVSANFDPRHYSDPDRLDITRHQEGQAENHV 373 Query: 451 RHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSS 507 G C G + + + Y + G + + Sbjct: 374 G------------FGHGIHYCLGATLARQEGEVALARLLETYPDLALADGDPEVRRA 418 >6G5O-A nrPDB Length = 399 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 50/146 (34%), Gaps = 21/146 (14%) Query: 353 RSVIKSNGGELTMGAIEK-MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVK 411 S+ + + K E+T V E +R+ P+T +D +H VK Sbjct: 231 NSIAYLAEHPEALERLRKEPEITGRAVEEMIRYFSPLTQMGRVVTED----THVCEHAVK 286 Query: 412 AGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQC 471 A + A RD +F+ +E V +R V + C Sbjct: 287 ADSRISLCWASANRDAAVFENPNEIVLDRKVNPH----------------VGFGFSHHNC 330 Query: 472 AGKDFVVLVARLFVIEIFRRYDSFDI 497 G + ++ + + ++ SF+I Sbjct: 331 LGATHARQILKILLQTLAQKVASFEI 356 >4WPZ-A nrPDB Length = 397 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 40/140 (28%), Gaps = 22/140 (15%) Query: 372 ELTKSVVYECLRFEPPVTA---QYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPK 428 E V E LRF P T ++ + + AG ++ A RDP+ Sbjct: 263 EAIPKAVDELLRFVPLTTTGGIIPRLTTAEVELS---GGQVLPAGAVVLPAVATANRDPE 319 Query: 429 IFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEI 488 +F+ + R N P G C G + + + I Sbjct: 320 VFEDGERLNVTR---------------ENNPHL-AFGAGIHHCLGAQLARIELQEALGAI 363 Query: 489 FRRYDSFDIEVGTSPLGSSV 508 R + V S L Sbjct: 364 LDRMPQVRLAVPESELRLKS 383 >4JBT-A nrPDB Length = 410 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 42/120 (35%), Gaps = 21/120 (17%) Query: 375 KSVVYECLRFEPPVT-AQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF-DR 432 ++ + E LR++ PV A +D+ + + GE + RD + Sbjct: 278 ETAIEETLRWDGPVIHLLMRFATEDIDLGD----AVIPRGEGVVMSYRAIGRDITVHGAD 333 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 AD+F R RH+ + G C G L A + + +F R+ Sbjct: 334 ADDFDITR------ATAARHISF---------GHGPHICPGAALARLEAAIALPALFTRF 378 >5YSW-A nrPDB Length = 441 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 42/149 (28%), Gaps = 25/149 (16%) Query: 361 GELTMGAIEKME-LTKSVVYECLRFEPPV-TAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 + + V E LR+ V + AK+DL A + AG + Sbjct: 296 RPAQLATLRDDPSRIADAVEELLRYLSVVNPGIFRFAKEDLE----FAGEHIPAGSTVVV 351 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVV 478 RD + + D R G G QC G+ Sbjct: 352 SVVATNRDARHWPDPD-LDLTRPRGPHLA----------------FGHGVHQCLGQQLAR 394 Query: 479 LVARLFVIEIFRRYDSFDIEVG--TSPLG 505 + + E+ RR + + V PL Sbjct: 395 MEMQAGYAELLRRLPNVRLAVPPEEVPLR 423 >5XNT-A nrPDB Length = 411 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 55/161 (34%), Gaps = 25/161 (15%) Query: 359 NGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYG 418 + E+ E ++L V E LR+ + K+D + ++K GE + Sbjct: 262 DDKEVYQELHENLDLVPQAVEEMLRYRFNLIKLDRTVKED----NDLLGVELKEGENVVV 317 Query: 419 YQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVV 478 + A D ++F+ A R N + T G C G Sbjct: 318 WMSAANLDEEMFEDAFTLNIHR---------------PNNKKHLTFGNGPHFCLGAPLAR 362 Query: 479 LVARLFVIEIFRRYD------SFDIEVGTSPLGSSVNFSSL 513 L A++ + +++ SF +E + + +SL Sbjct: 363 LEAKIALTTFLKKFKHIEAVPSFQLEDNLTDSATGQTLTSL 403 >5OMS-A nrPDB Length = 409 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 43/133 (32%), Gaps = 23/133 (17%) Query: 366 GAIEKMELTKSVVYECLRFEPPVTAQY-GRAKKDLVIESHDAAFKVKAGEMLYGYQPLAT 424 ++ L + E LR+ P+ + + K + I A + AG + A Sbjct: 272 EVVDDPTLIPRAIAEGLRWTSPIWSATARISTKPVTI----AGVDLPAGTPVMLSYGSAN 327 Query: 425 RDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE-TPTVGNKQCAGKDFVVLVARL 483 D ++ ++ R P GN CAG F V R+ Sbjct: 328 HDTGKYEAPSQYDLHR-----------------PPLPHLAFGAGNHACAGIYFANHVMRI 370 Query: 484 FVIEIFRRYDSFD 496 + E+F + + Sbjct: 371 ALEELFEAIPNLE 383 >6A7J-A nrPDB Length = 411 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 42/133 (31%), Gaps = 22/133 (16%) Query: 375 KSVVYECLRFEPPVT-AQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF-DR 432 + V+ E LR+ P + A +D+ + + GE L RD + + Sbjct: 274 EGVIEETLRWNTPTSHVLIRFATEDIEVGDKV----LPKGEGLVVSFGALGRDEEQYGPT 329 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRY 492 A +F R G C G L A + + ++ R+ Sbjct: 330 AGDFDATR----------------TPNRHIAFGHGPHVCPGAALSRLEAGIALPALYERF 373 Query: 493 DSFDIEVGTSPLG 505 D+ V + L Sbjct: 374 PELDLAVPAAELR 386 >2ZBZ-A nrPDB Length = 412 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 45/133 (33%), Gaps = 21/133 (15%) Query: 373 LTKSVVYECLRFEPPV-TAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFD 431 L V E LR+ A A D+ +E ++AGE + +A RD +++ Sbjct: 276 LVPGAVEELLRYLAIADIAGGRVATADIEVEGQL----IRAGEGVIVVNSIANRDGTVYE 331 Query: 432 RADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRR 491 D R H+ + G QC G++ L + + + R Sbjct: 332 DPDALDIHR-------SARHHLAF---------GFGVHQCLGQNLARLELEVILNALMDR 375 Query: 492 YDSFDIEVGTSPL 504 + + V L Sbjct: 376 VPTLRLAVPVEQL 388 >5KYO-A nrPDB Length = 430 Score = 52.4 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 26/137 (18%), Positives = 46/137 (33%), Gaps = 22/137 (16%) Query: 371 MELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 L + E R P V+ + ++++ + +KAG+M+ + D Sbjct: 300 PSLIDDALLEFFRRFPVVS-----SAREVLRDQEFEGVLLKAGDMVMAPTVVVAMDDARN 354 Query: 431 DRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFR 490 + EF R + T G+ C G + ++ + E F Sbjct: 355 EDPLEFRLGRKARQHS----------------TFGKGSHTCPGAHLARMEMKVVLREWFA 398 Query: 491 RYDSFDIEVGTSPLGSS 507 R F IE +PL S Sbjct: 399 RIPEFRIE-DDAPLRYS 414 >3NV6-A nrPDB Length = 452 Score = 51.6 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 36/125 (28%), Gaps = 21/125 (16%) Query: 380 ECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPE 439 E R P V+ AK + +K G+M+ L D + Sbjct: 329 EMFRRFPVVSEARMVAK-----DQEYKGVFLKRGDMILLPTALHGLDDAANPEPWKLDFS 383 Query: 440 RFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEV 499 R T G +CAG + + + E +R F + Sbjct: 384 R----------------RSISHSTFGGGPHRCAGMHLARMEVIVTLEEWLKRIPEFSFKE 427 Query: 500 GTSPL 504 G +P+ Sbjct: 428 GETPI 432 >6FSH-A nrPDB Length = 398 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 39/124 (31%), Gaps = 21/124 (16%) Query: 375 KSVVYECLRFEP-PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 V E +R+ P A +D+++ +K GE + P+A RD + A Sbjct: 270 DRAVDELIRYLTVPYAPTPRTAVEDVMVADQV----IKEGETVLCSLPMANRDRALLPDA 325 Query: 434 DEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 D R G C G L R+ ++RR+ Sbjct: 326 DRLDVTR----------------TPVPHVAFGHGIHHCLGAALTRLQLRIAYTALWRRFP 369 Query: 494 SFDI 497 + + Sbjct: 370 ALQL 373 >4TX3-A nrPDB Length = 404 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 39/124 (31%), Gaps = 21/124 (16%) Query: 375 KSVVYECLRFEP-PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRA 433 V E +R+ P A +D+++ +K GE + P+A RD + A Sbjct: 276 DRAVDELIRYLTVPYAPTPRTAVEDVMVADQV----IKEGETVLCSLPMANRDRALLPDA 331 Query: 434 DEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 493 D R G C G L R+ ++RR+ Sbjct: 332 DRLDVTR----------------TPVPHVAFGHGIHHCLGAALTRLQLRIAYTALWRRFP 375 Query: 494 SFDI 497 + + Sbjct: 376 ALQL 379 >6G71-A nrPDB Length = 405 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 31/114 (27%), Gaps = 20/114 (17%) Query: 368 IEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 + +L +V E +R+ P+ + D ++ + + G L A RD Sbjct: 263 LRDPKLWGAVFEESIRWVAPIGMVPRQTVVDTELDGYF----IPRGAKLGLCILSANRDR 318 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVA 481 ++ D F ER G C G Sbjct: 319 SVWSDPDRFDIERGSEAHLA----------------FGKGVHVCLGAWAARSQV 356 >3WEC-A nrPDB Length = 419 Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 45/134 (33%), Gaps = 23/134 (17%) Query: 365 MGAIE-KMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLA 423 + + ++ V E LRFEPP A +D + + + G+ + Sbjct: 276 FEQVRANPQFIENAVAEVLRFEPPAHEAGRIALEDCEVSGAN----ITKGDAVMVLLASG 331 Query: 424 TRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARL 483 R + +R D F R + + G C G + + Sbjct: 332 NR--EAVERGDTFSVTR----------------PDVSSLSYGRGIHHCLGSALANSMLQH 373 Query: 484 FVIEIFRRYDSFDI 497 F+ E+ +RY S ++ Sbjct: 374 FLRELSQRYRSIEV 387 >5L1U-A nrPDB Length = 401 Score = 48.5 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 22/143 (15%), Positives = 36/143 (25%), Gaps = 23/143 (16%) Query: 369 EKMELTKSVVYECLRF----EPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLAT 424 E L + V E LR + A D+ + ++ G+ + A Sbjct: 263 EDPGLAPAAVEEILRLGVGGKGSNALIPRYAHGDITV----GETVIRTGDAVMLAIGAAN 318 Query: 425 RDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLF 484 D + F F R G + C G+ + Sbjct: 319 YDDRAFPDGGLFDLTRVRPRSH---------------LAFGHGARHCIGRTLARIELTAV 363 Query: 485 VIEIFRRYDSFDIEVGTSPLGSS 507 +FRR + V L Sbjct: 364 FERLFRRLPDLRLAVPEESLRWQ 386 >4UBS-A nrPDB Length = 393 Score = 48.5 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 36/123 (29%), Gaps = 22/123 (17%) Query: 370 KMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKI 429 + L + V E LRF A +D+ + A ++A E + + RD Sbjct: 261 EPGLMPAAVEELLRFLSIADGLLRVATEDIEV----AGTTIRADEGVVFATSVINRDAAG 316 Query: 430 FDRADEFVPERFVGEEGEKLLRHVLWSNGPETET-PTVGNKQCAGKDFVVLVARLFVIEI 488 F D W G QC G++ + + + Sbjct: 317 FAEPDALD-----------------WHRSARHHVAFGFGIHQCLGQNLARAEMEIALGTL 359 Query: 489 FRR 491 F R Sbjct: 360 FER 362 >3A50-A nrPDB Length = 411 Score = 48.5 bits (114), Expect = 8e-06, Method: Composition-based stats. Identities = 80/378 (21%), Positives = 115/378 (30%), Gaps = 99/378 (26%) Query: 142 MPSTELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKEL 201 MP+T ++ +DP P H +L+ L+ +S R E + +E+ D L L Sbjct: 79 MPATPTP----MMILMDP--PDHTRLRKLVG---RSFTVRRMNELEPRITEIADGLLAGL 129 Query: 202 SLKGKADFG------------------GSSDGTAFNFLARAFYGTNPADTKLKADAPGLI 243 G D + D F+ + +PAD K A Sbjct: 130 PTDGPVDLMREYAFQIPVQVICELLGLPAEDRDDFSAWSSVLVDDSPADDKNAA------ 183 Query: 244 TKWVLFNLHPLLSIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKL 303 + LH LS L R EP S A+ D RL S E++ A L Sbjct: 184 ----MGKLHGYLSDLLERKRTEPDDALLSSLLAVSDMDGDRL------SQEELVAMAMLL 233 Query: 304 GISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGEL 363 I+ E T NL+ G +L H +L E Sbjct: 234 LIAGHETTVNLI---------GNGVL--------ALLTHPDQRKLLAE------------ 264 Query: 364 TMGAIEKMELTKSVVYECLRFEPPVT-AQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPL 422 L S V E LRF+ PV+ A +D+ + + AGEM+ Sbjct: 265 ------DPSLISSAVEEFLRFDSPVSQAPIRFTAEDVT----YSGVTIPAGEMVMLGLAA 314 Query: 423 ATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVAR 482 A RD D R + G C G L R Sbjct: 315 ANRDADWMPEPDRLDITR----------------DASGGVFFGHGIHFCLGAQLARLEGR 358 Query: 483 LFVIEIFRRYDSFDIEVG 500 + + +F + VG Sbjct: 359 VAIGRLFADRPELALAVG 376 >3WVS-A nrPDB Length = 401 Score = 48.2 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 43/132 (32%), Gaps = 22/132 (16%) Query: 368 IEKMELTKSVVYECLRFEP--PVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATR 425 ++ EL S V E RF P +A A++D+ + V+AGE + A R Sbjct: 268 LDDPELIPSAVEELFRFVPLGSGSAAPRYAREDIEVGGTL----VRAGEPVLVALGAANR 323 Query: 426 DPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFV 485 D F+ +E +R G C G L + + Sbjct: 324 DGLRFEDPEEIKLDR----------------PSNHHIGFGHGIHHCLGAPLARLELQEAL 367 Query: 486 IEIFRRYDSFDI 497 + R + + Sbjct: 368 RALLERLPTLKV 379 >4Z5Q-A nrPDB Length = 423 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 26/137 (18%), Positives = 39/137 (28%), Gaps = 22/137 (16%) Query: 356 IKSNGGELTMGAIEKMELTKSVVYECLRFEPPVT--AQYGRAKKDLVIESHDAAFKVKAG 413 + EL E + V E LRF P A +D+ + V+ G Sbjct: 278 VLQQRRELWTRLCADPEAIPAAVEELLRFVPFAANGISPRYALEDMTV----GGVLVREG 333 Query: 414 EMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAG 473 E + RD +FD ADE V +R G C G Sbjct: 334 EPVIVDTSAVNRDGLVFDNADEVVIDR----------------ADNRHMVFGHGAHHCLG 377 Query: 474 KDFVVLVARLFVIEIFR 490 + + + + Sbjct: 378 AHLARVELQEALKALVE 394 >4C9K-A nrPDB Length = 421 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 38/135 (28%), Gaps = 21/135 (15%) Query: 369 EKMELTKSVVYECLRFEPPVTAQYGR-----AKKDLVIESHDAAFKVKAGEMLYGYQPLA 423 E + E L+ + V + R + +V + +K G+++ L Sbjct: 274 RHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALH 333 Query: 424 TRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARL 483 D + D R T G +CAG L + Sbjct: 334 GLDDRHHDDPMTVDLSR----------------RDVTHSTFAQGPHRCAGMHLARLEVTV 377 Query: 484 FVIEIFRRYDSFDIE 498 + E R F ++ Sbjct: 378 MLQEWLARIPEFRLK 392 >2YJN-B nrPDB Length = 381 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 28/74 (37%), Gaps = 4/74 (5%) Query: 378 VYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFV 437 V E LR P + + A ++ + H + GE + A RDP++F D Sbjct: 259 VAEVLRLHPALHLERRTATAEVRLGEHV----IGEGEEVVVVVAAANRDPEVFAEPDRLD 314 Query: 438 PERFVGEEGEKLLR 451 +R + R Sbjct: 315 VDRPDADRALSAHR 328 >2IJ7-A nrPDB Length = 396 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 40/132 (30%), Gaps = 20/132 (15%) Query: 369 EKMELTKSVVYECLRFE-PPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDP 427 EK EL + V E LR A D+ + V+ GE++ A DP Sbjct: 261 EKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVL----VRKGELVLVLLEGANFDP 316 Query: 428 KIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIE 487 + F +R N G C G A++ + Sbjct: 317 EHFPNPGSIELDR---------------PNPTSHLAFGRGQHFCPGSALGRRHAQIGIEA 361 Query: 488 IFRRYDSFDIEV 499 + ++ D+ V Sbjct: 362 LLKKMPGVDLAV 373 >6AUN-A nrPDB Length = 752 Score = 37.0 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 51/159 (32%), Gaps = 29/159 (18%) Query: 315 LFATCFNTWGGMKILFPN--MVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKME 372 F NT + LF N VK I A + H R+ EE + ++ N T I Sbjct: 3 FFGRLVNTLSSVTNLFSNPFRVKEISVADYTSHERVREEGQLILFQNASNRTWDCILVSP 62 Query: 373 LTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDR 432 + +ES + L +Q +++ P ++ Sbjct: 63 RNPHS-----------------GFRLFQLESE--------ADALVNFQQFSSQLPPFYES 97 Query: 433 ADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQC 471 + + + + + + H W+ +G ++C Sbjct: 98 SVQVLHVEVLQHLSDLIRSHPSWTVTHLAVE--LGIREC 134 >6H03-D nrPDB Length = 821 Score = 35.4 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 58/245 (23%), Positives = 91/245 (37%), Gaps = 36/245 (14%) Query: 90 RKYNSTVYRVNMPPGAFIAENPQVVALLDG-----KSFPVLFDVDKVEKK-DLFTGTYMP 143 + Y V + FI NP+ + L + P L+D + D + Y+ Sbjct: 224 KSYQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYGTHYLQ 283 Query: 144 STELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQA-TYSELFDSLEKELS 202 S L G YR+L Y+D + K ++ KSS +F + EL ++L+ Sbjct: 284 SGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWHFVVKFSSHGCKELENALKAASG 343 Query: 203 -----LKGKADFGGSSDG--TAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLL 255 L+G+ G G + ++L NPA K + A W Sbjct: 344 TQNNVLRGEPFIRGGGAGFISGLSYLEL----DNPAGNKRRYSA------WA------ES 387 Query: 256 SIGLPRVIEEPLIHTFSL----PPALVKSDYQR--LYEFFLESAGEILVEADKLGISREE 309 LP+VI++ L + L P A VK Y + L E+ E G++ E Sbjct: 388 VTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVE 447 Query: 310 ATHNL 314 TH L Sbjct: 448 GTHCL 452 >3EB7-A nrPDB Length = 589 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 57/145 (39%), Gaps = 32/145 (22%) Query: 57 IPGNYGLPIVGPI---------------KDRWDYFYDQGAEEFFKSRIRKYNSTVYRVNM 101 I G G+P+VGPI K +W+ F +Q E +I +Y + Sbjct: 17 ILGKLGVPLVGPIVSLYSTLIDVLWPGGKSQWEIFMEQ-VEALINQKIAEYARAKALAEL 75 Query: 102 PPGAFIAENPQ--VVALLDGKSFP----VLFDV-DKVEKKDLFTGTYMPSTELTGGYRIL 154 + N Q + AL + + P VL DV ++ E D YMPS +R+ Sbjct: 76 EG---LGNNYQLYLTALEEWQENPSSTRVLRDVRNRFEILDSLFTQYMPS------FRVT 126 Query: 155 SYLDPSEPKHEKLKNLLFFLLKSSR 179 Y P + + NL LLK + Sbjct: 127 GYEVPLLSVYAQAANLHLLLLKDAS 151 >4BPT-A nrPDB Length = 272 Score = 33.1 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 45/209 (21%), Positives = 78/209 (37%), Gaps = 28/209 (13%) Query: 107 IAENPQVVALLDGKS----FPVLFDVDKVEKKDLFTGTYMPSTELTGGYRILSYLDPSEP 162 I + P+V L K+ PV + E +L Y P+ L Y+ + Sbjct: 61 IPQLPEVSERLKAKTGWQVAPVAALISAREFFELLAEKYFPAATFIRSEEELDYVQEPDI 120 Query: 163 KHEKLKNLLFFLLKSSRNRIFPEFQATYS-ELFDSLEKELSLKGK-----ADFGGSSDGT 216 HE LF +R++ EF Y+ ++ E++ L + +FG Sbjct: 121 FHE-----LFGHCPMLTDRVYAEFVHDYACKVLTFPEQDWPLLQRMFWFTVEFGLIKTPK 175 Query: 217 AFNFLARAFYGTNPADTK-LKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFSLPP 275 + +++D P I LF+ P+++ +P I++ P Sbjct: 176 GLRAYGGGILSSISETVYCVESDIPVRI----LFD--PVVAFRMPYRIDQ------LQPV 223 Query: 276 ALVKSDYQRLYEFFLESAGEILVEADKLG 304 V YQ LY+F L G+ + A +LG Sbjct: 224 YFVIDSYQNLYDFVLSDMGKFMDRARELG 252 >2NYA-A nrPDB Length = 792 Score = 33.1 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 35/98 (35%), Gaps = 4/98 (4%) Query: 369 EKMELTKSVVYECLRFEPPVT--AQYGRAKKDLVIESHDAAFKVKAG--EMLYGYQPLAT 424 +K EL +YE L P V+ A+ L ES + F ++ G E + Sbjct: 546 KKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFYLQKGLFEEYAWFGRGHG 605 Query: 425 RDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 462 D FD + R+ G++ N P + Sbjct: 606 HDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVK 643 >4W8Z-A nrPDB Length = 344 Score = 32.4 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 2/59 (3%) Query: 41 LTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYF--YDQGAEEFFKSRIRKYNSTVY 97 L V +K LP + + GP K+ W+ ++ +E+ + RI+KY ++ Sbjct: 206 LGVKNSETNKSLPSYATLKFSDVEVFGPGKNTWEVLAQFNNSYKEYLRRRIKKYQRIIF 264 >5KB6-A nrPDB Length = 363 Score = 32.0 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%) Query: 230 PADTKLKADAPGLITKWVLFNL-HPLLSIGLPRVIEEPLIHTFSLPP---ALVKSDYQRL 285 P KLK +AP +++ VLF + +PLL I V+++ + +SL P L + ++ L Sbjct: 9 PKPKKLKVEAPQALSENVLFGMGNPLLDISA--VVDKDFLDKYSLKPNDQILAEDKHKEL 66 Query: 286 YE 287 ++ Sbjct: 67 FD 68 >1Z7A-A nrPDB Length = 308 Score = 32.0 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 33 ASGSETPDLTVATRTGSKDLPIRNIPG-NYGLPIVGPIKDRWDYFYDQGA 81 AS +E P L + + D+ + G N G +KD +D Y++GA Sbjct: 199 ASTAEKPHLVIPYTLDTNDMRFTQVQGFNNGEQFFQYLKDAFDVLYEEGA 248 >3CQL-A nrPDB Length = 243 Score = 32.0 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 32/90 (35%), Gaps = 13/90 (14%) Query: 67 GPIKDRWDYFYDQGAEEFFKSRIRKYNSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLF 126 GPI+ W+Y Y E RVN+ + +V++ F + Sbjct: 115 GPIQLSWNYNYGPCGE-------------ALRVNLLGNPDLVATDRVISFKTALWFWMTP 161 Query: 127 DVDKVEKKDLFTGTYMPSTELTGGYRILSY 156 K D+ TG + PS T R+ Y Sbjct: 162 QAPKPSCHDVITGRWQPSAADTAAGRLPGY 191 >3AF5-A nrPDB Length = 651 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 41/107 (38%), Gaps = 15/107 (14%) Query: 300 ADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSN 359 A+ + + REEA L+ G K+L P M +GRA +E+ V++ Sbjct: 398 ANDIQMPREEAEKRLIEVIHNTIKRGGKVLIPAMA--VGRA---------QEVMMVLEEY 446 Query: 360 GGELTMGAIEKMELTKSVVYECLRFEPPVT-AQYGRAKKDLVIESHD 405 +G IE +++E R ++ + E ++ Sbjct: 447 AR---IGGIEVPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYN 490 >3ICS-A nrPDB Length = 588 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 7/81 (8%) Query: 88 RIRKYNSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEK-KDLFTGTYMPSTE 146 +I K T+ N+ E V+ L G P++ + +E+ K LFT +P T+ Sbjct: 118 KINKEEKTITIKNVTTNETYNEAYDVLILSPGAK-PIVPSIPGIEEAKALFTLRNVPDTD 176 Query: 147 LTGGYRILSYLDPSEPKHEKL 167 RI +Y+D +P+H + Sbjct: 177 -----RIKAYIDEKKPRHATV 192 >5JOV-A nrPDB Length = 955 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 39/113 (34%), Gaps = 15/113 (13%) Query: 46 RTGSKDLPIRNIPGNYGLPIVGPIKDRWD-YFYDQGAEEFFKSRIRKYNSTVYRVNMPPG 104 + G K + G G + + D FY G + + + N +++ N Sbjct: 128 KGGGKTFTPIEVEGTKGYTVCQVFESPEDEAFYGLGQHQADEFNYKGKNEELFQYNTKVS 187 Query: 105 -AFIAENPQVVALLDGKSF-------------PVLFDVDKVEKKDLFTGTYMP 143 F+ N LLD SF + DK ++ TGTY+P Sbjct: 188 VPFVVSNKNYGILLDSYSFCRFGNPNDYSQLNRIFKLYDKTGQEGALTGTYVP 240 >6NT6-A nrPDB Length = 392 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 22/36 (61%) Query: 144 STELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSR 179 S E G YR+++Y +P+EP+ L L+ + L+ + Sbjct: 307 SKECAGLYRLIAYEEPAEPESHFLSGLILWHLQQQQ 342 >5ZCR-A nrPDB Length = 728 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 5/78 (6%) Query: 127 DVDKVEKKDLFTGTYMPSTELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEF 186 D D EKK ++ G YM S T L +L P P + + FLL NR+ +F Sbjct: 565 DFDNFEKKIVYFG-YMKSLVAT----TLKFLSPGVPDIYQGTEVWRFLLTDPDNRMAVDF 619 Query: 187 QATYSELFDSLEKELSLK 204 + L + EK L L Sbjct: 620 RKLRELLNNLTEKNLELS 637 >3BU7-A nrPDB Length = 394 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 49 SKDLPIRNIPGNYGLPIVGPIKDRWDYFY 77 + D+P+ + P YG P + P D+WD Y Sbjct: 219 TTDIPLNDSPLTYGGPALLPQLDKWDKPY 247 >5VDN-A nrPDB Length = 463 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 264 EEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFAT 318 E P +HT S+P A++K+ L LE+ E+ V+ I RE AT NL + Sbjct: 234 EGPKLHTESVPKAVIKNADGSL-TLQLENGTEVTVDHLIWAIGREPATDNLNLSV 287 >5D2Y-A nrPDB Length = 264 Score = 29.7 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 60/155 (38%), Gaps = 13/155 (8%) Query: 289 FLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIG--------RA 340 F ++ IL ADK+ I+ + L T+G ++ KR+ Sbjct: 87 FETASELILRGADKVEINTAAVENPSLITQIAQTFGSQAVVVYIAAKRVDGEFMVFTYSG 146 Query: 341 GHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQ-----YGRA 395 L + + V K GE+ +G+I+++ E +RF P+T G Sbjct: 147 KKNTGILLRDWVVEVEKRGAGEIVLGSIDRLGTKSGYDTEMIRFVRPLTTLPIIAHRGAG 206 Query: 396 KKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIF 430 K + +E+ A + ++ ++ + R+ K + Sbjct: 207 KMEHFLEAFLAGADAAKADSVFHFREIDVRELKEY 241 >2RHI-A nrPDB Length = 345 Score = 28.1 bits (61), Expect = 9.1, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 14/33 (42%) Query: 427 PKIFDRADEFVPERFVGEEGEKLLRHVLWSNGP 459 P+ + D F E+++ E G + + P Sbjct: 222 PQDYPDPDNFCWEKYLEETGASAVPTWAFKVRP 254 >4M8Z-A nrPDB Length = 351 Score = 28.1 bits (61), Expect = 9.6, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 20/44 (45%) Query: 51 DLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKYNS 94 D PI+ +P + +P P+ YD+ + F ++ Y S Sbjct: 22 DKPIKELPASIAIPKEKPLTGEQQKMYDEVLKHFSNPDLKVYTS 65 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.132 0.367 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,319,562 Number of Sequences: 36641 Number of extensions: 870061 Number of successful extensions: 2454 Number of sequences better than 10.0: 177 Number of HSP's better than 10.0 without gapping: 170 Number of HSP's successfully gapped in prelim test: 75 Number of HSP's that attempted gapping in prelim test: 2073 Number of HSP's gapped (non-prelim): 276 length of query: 518 length of database: 10,336,785 effective HSP length: 101 effective length of query: 417 effective length of database: 6,636,044 effective search space: 2767230348 effective search space used: 2767230348 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.1 bits)