BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q93ZN9 (461 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3EI8-A nrPDB 889 0.0 3QGU-A nrPDB 570 e-163 4FL0-A nrPDB 564 e-161 3ASB-A nrPDB 313 1e-85 2X5D-A nrPDB 105 4e-23 1GDE-A nrPDB 97 2e-20 1O4S-A nrPDB 88 8e-18 2O1B-A nrPDB 84 1e-16 2Z61-A nrPDB 83 2e-16 3JTX-A nrPDB 82 6e-16 5YHV-A nrPDB 80 1e-15 1GC4-A nrPDB 77 1e-14 1V2E-A nrPDB 77 2e-14 1XI9-A nrPDB 74 1e-13 4MY5-A nrPDB 74 1e-13 1J32-A nrPDB 74 2e-13 3H14-A nrPDB 70 1e-12 4CVQ-A nrPDB 70 2e-12 2DOU-A nrPDB 68 8e-12 3ELE-A nrPDB 68 1e-11 5WMH-A nrPDB 67 2e-11 1U08-A nrPDB 63 2e-10 3EZS-A nrPDB 63 3e-10 6F77-B nrPDB 62 4e-10 3OP7-A nrPDB 62 5e-10 6F35-A nrPDB 60 2e-09 3DYD-A nrPDB 57 2e-08 4M2J-A nrPDB 55 6e-08 2ZC0-A nrPDB 55 7e-08 3AV7-A nrPDB 55 9e-08 1X0M-A nrPDB 54 1e-07 3T32-A nrPDB 53 2e-07 1BW0-A nrPDB 53 4e-07 3TCM-A nrPDB 52 7e-07 1VP4-A nrPDB 51 1e-06 3B46-A nrPDB 51 1e-06 3PDX-A nrPDB 50 2e-06 2ZYJ-A nrPDB 50 3e-06 4R2N-A nrPDB 49 4e-06 3FVS-A nrPDB 49 4e-06 4WP0-A nrPDB 49 5e-06 3B1C-A nrPDB 49 6e-06 2ZJG-A nrPDB 47 1e-05 6EZL-A nrPDB 46 3e-05 4RAE-A nrPDB 46 4e-05 3GET-A nrPDB 45 5e-05 3FKD-A nrPDB 45 8e-05 3FDB-A nrPDB 45 1e-04 3DZZ-A nrPDB 44 1e-04 1YIY-A nrPDB 44 2e-04 3LY1-A nrPDB 44 2e-04 1UU1-A nrPDB 44 2e-04 4DQ6-A nrPDB 44 2e-04 3CQ5-A nrPDB 43 2e-04 3FTB-A nrPDB 42 4e-04 3P1T-A nrPDB 42 4e-04 5DJ3-A nrPDB 41 0.001 5TON-A nrPDB 41 0.001 4IX8-A nrPDB 41 0.001 1YAA-A nrPDB 41 0.001 1AY8-A nrPDB 41 0.001 1LC8-A nrPDB 40 0.002 6C3C-A nrPDB 40 0.002 2GB3-A nrPDB 40 0.002 1TAR-A nrPDB 40 0.002 3FFH-A nrPDB 40 0.003 2O0R-A nrPDB 40 0.003 3IHJ-A nrPDB 39 0.003 1D2F-A nrPDB 39 0.006 3G7Q-A nrPDB 38 0.010 2X8U-A nrPDB 38 0.011 4GDY-A nrPDB 38 0.012 3IF2-A nrPDB 38 0.012 4WBT-A nrPDB 37 0.018 3L8A-A nrPDB 37 0.020 1M4N-A nrPDB 37 0.020 3G0T-A nrPDB 37 0.024 3II0-A nrPDB 37 0.025 5Z0Q-C nrPDB 37 0.025 1C7O-A nrPDB 36 0.038 3MEB-A nrPDB 36 0.045 3PD6-B nrPDB 35 0.048 1IJI-A nrPDB 35 0.050 2ZY3-A nrPDB 35 0.055 4BMK-A nrPDB 35 0.056 3NRA-A nrPDB 35 0.065 2ZY2-A nrPDB 35 0.083 6HNB-A nrPDB 35 0.088 3K7Y-A nrPDB 34 0.14 3FDD-A nrPDB 34 0.15 3FSL-A nrPDB 34 0.15 2X5F-A nrPDB 33 0.23 1IAY-A nrPDB 33 0.27 3F6T-A nrPDB 33 0.32 2HOR-A nrPDB 32 0.45 4H51-A nrPDB 32 0.66 1COJ-A nrPDB 31 1.0 3BWN-A nrPDB 31 1.2 4RKC-A nrPDB 31 1.3 4F5M-A nrPDB 31 1.4 1QO0-A nrPDB 31 1.4 4WB0-B nrPDB 30 1.6 4OC9-A nrPDB 30 2.7 3EUC-A nrPDB 30 2.7 1E0T-A nrPDB 28 5.7 >3EI8-A nrPDB Length = 432 Score = 889 bits (2296), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/426 (99%), Positives = 425/426 (99%) Query: 36 MAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVIS 95 MAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVIS Sbjct: 1 MAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVIS 60 Query: 96 LGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD 155 LGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD Sbjct: 61 LGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD 120 Query: 156 DVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 215 DVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY Sbjct: 121 DVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 180 Query: 216 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY Sbjct: 181 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 240 Query: 276 AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 335 AMYMSDDNPRSIFEIPGAEEVAMETASFS YAGFTGVRLGWTVIPKKLLYSDGFPVAKDF Sbjct: 241 AMYMSDDNPRSIFEIPGAEEVAMETASFSNYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 300 Query: 336 NRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK 395 NRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK Sbjct: 301 NRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK 360 Query: 396 NAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 455 NAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR Sbjct: 361 NAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 420 Query: 456 FKQLYK 461 FKQLYK Sbjct: 421 FKQLYK 426 >3QGU-A nrPDB Length = 449 Score = 570 bits (1470), Expect = e-163, Method: Compositional matrix adjust. Identities = 275/403 (68%), Positives = 326/403 (80%), Gaps = 3/403 (0%) Query: 59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAH 118 V RN N KL+AGYLFPEIARRR AH K PDA++ISLGIGDTTEP+P+ I AMAK A Sbjct: 37 VQRNENFGKLRAGYLFPEIARRRKAHQEKNPDAKIISLGIGDTTEPLPKYIADAMAKAAA 96 Query: 119 ELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNV 178 L+T EGYSGYGAEQG LR A+A TFYG G D++F+SDG+KCDI+R+Q+MFGS Sbjct: 97 GLATREGYSGYGAEQGQGALREAVASTFYGHAGRAADEIFISDGSKCDIARIQMMFGSKP 156 Query: 179 TIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIF 238 T+AVQDPSYP YVD+SV+MG TG N + IEYM C P+N FFPDLS RTDIIF Sbjct: 157 TVAVQDPSYPVYVDTSVMMGMTGDHNG--TGFDGIEYMVCNPDNHFFPDLSKAKRTDIIF 214 Query: 239 FCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSD-DNPRSIFEIPGAEEVA 297 FCSPNNPTGAAATR QLT+LV FA+KNGSI+VYD+AYA+Y+S+ D P++I+EIPGA+EVA Sbjct: 215 FCSPNNPTGAAATRAQLTELVNFARKNGSILVYDAAYALYISNPDCPKTIYEIPGADEVA 274 Query: 298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC 357 +ET SFSKYAGFTGVRLGWTV+PK L Y++G PV D+NR++ TCFNGASNI QAG LAC Sbjct: 275 IETCSFSKYAGFTGVRLGWTVVPKALKYANGEPVHADWNRVMTTCFNGASNIVQAGGLAC 334 Query: 358 LTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEIL 417 L PEGL+ M+ +I FYKEN I+ TFT +G+ VYGG +APY+WV FP + SWDVFAEIL Sbjct: 335 LQPEGLKEMNAMIKFYKENAQILKTTFTEMGFSVYGGDDAPYIWVGFPGKPSWDVFAEIL 394 Query: 418 EKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 E+ ++VTTPGSG+GP GEGFVR SAFG RENILEA RRFK+ Y Sbjct: 395 ERCNIVTTPGSGYGPAGEGFVRASAFGSRENILEAVRRFKEAY 437 >4FL0-A nrPDB Length = 456 Score = 564 bits (1453), Expect = e-161, Method: Compositional matrix adjust. Identities = 257/410 (62%), Positives = 322/410 (78%) Query: 51 EKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVIT 110 +K+ TK+ RN N+ KL+ YLFPEI RR H+ K+P+ Q+ISLG GDTTEPIPE IT Sbjct: 30 KKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQIT 89 Query: 111 SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL 170 S M+ AH LST+EGY GYG EQG K LR AIA+TFY L + ++VFVSDGA+ DISRL Sbjct: 90 SHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL 149 Query: 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST 230 Q++ GSNVTIAVQDP++PAY+DSSVI+GQTG F+ +KY N+ YM C P N FFPDL+ Sbjct: 150 QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAM 209 Query: 231 VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 290 RTD+IFFCSPNNPTG A+R+QL QLV+FAK NGSII++DSAYA ++ D +PRSI+EI Sbjct: 210 TPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI 269 Query: 291 PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 PGA EVA+E +SFSK+AGFTGVRLGW++IP +LLYS+GFP+ DF+RI+ T FNGASNI+ Sbjct: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIA 329 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 QAG LACL+ GL+ + V +YKEN I++DT SLG VYGG NAPY+WVHF SW Sbjct: 330 QAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW 389 Query: 411 DVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 DVF EILE TH++T PGSGFGPGGE ++R+S FG R++I+EA +R + + Sbjct: 390 DVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFF 439 >3ASB-A nrPDB Length = 400 Score = 313 bits (802), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 167/405 (41%), Positives = 243/405 (60%), Gaps = 24/405 (5%) Query: 59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAH 118 + RN + L YLF ++ +R + L+ P VI+L IGDTT+P+ + A A Sbjct: 1 MKRNPHFVSLTKNYLFADLQKRVAQFRLENPQHTVINLSIGDTTQPLNASVAEAFASSIA 60 Query: 119 ELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNV 178 LS+ GYG + G LR +++ FY G + ++F+SDGAK D+ RL FG N Sbjct: 61 RLSSPTTCRGYGPDFGLPALRQKLSEDFYRGF-VDAKEIFISDGAKVDLFRLLSFFGPNQ 119 Query: 179 TIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIF 238 T+A+QDPSYPAY+D + + G I + C EN FFP+ DI+ Sbjct: 120 TVAIQDPSYPAYLDIARLTGAK-----------EIIALPCLQENAFFPEFPEDTHIDILC 168 Query: 239 FCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVA 297 CSPNNPTG ++QL +V +A ++ +I++D+AY+ ++SD + P+SIFEIP A A Sbjct: 169 LCSPNNPTGTVLNKDQLRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCA 228 Query: 298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC 357 +E SFSK GF G+RLGWTVIP++L Y+DG V +D+ R + T FNGAS +Q +A Sbjct: 229 IEINSFSKPLGFAGIRLGWTVIPQELTYADGHFVIQDWERFLSTTFNGASIPAQEAGVAG 288 Query: 358 LT--PEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ---SSWDV 412 L+ P+ LEA+H +Y+EN++++ + G++V+GG++APY+WV P Q S D+ Sbjct: 289 LSILPQ-LEAIH----YYRENSDLLRKALLATGFEVFGGEHAPYLWVK-PTQANISDRDL 342 Query: 413 FAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFK 457 F L + H+ TPG GFG G GFVR S+ G RE+IL AC R + Sbjct: 343 FDFFLREYHIAITPGIGFGRSGSGFVRFSSLGKREDILAACERLQ 387 >2X5D-A nrPDB Length = 412 Score = 105 bits (263), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 97/398 (24%), Positives = 168/398 (42%), Gaps = 47/398 (11%) Query: 78 ARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKP 137 ARRR +I L +G+ P P I + A E GY +G Sbjct: 32 ARRRGE--------DIIDLSMGNPDGPTPPHIVEKLCTVAQR----EDTHGYSTSRGIPR 79 Query: 138 LRAAIAKTFYGGLGIGDD---DVFVSDGAKCDISRLQV-MFGSNVTIAVQDPSYPAYVDS 193 LR AI+ + + D + V+ G+K ++ L + TI V +PSYP ++ Sbjct: 80 LRRAISHWYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATLDHGDTILVPNPSYPIHIYG 139 Query: 194 SVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI-----IFFCSPNNPTGA 248 +VI G + + P FF +L R I + P+NPT Sbjct: 140 AVIAG------------AQVRSVPLVPGIDFFNELERAIRESIPKPRMMILGFPSNPTAQ 187 Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAMETASFSKYA 307 + ++V AK+ ++V+D AYA + D SI ++PGA+++A+E + SK Sbjct: 188 CVELDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFTLSKSY 247 Query: 308 GFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMH 367 G R+G+ V +L+ + RI G Q A+A L + + + Sbjct: 248 NMAGWRIGFMVGNPELVSA--------LARIKSYHDYGTFTPLQVAAIAALEGDQ-QCVR 298 Query: 368 KVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP----NQSSWDVFAEILEKTHVV 423 + Y++ ++++ G+ V K + YVW P + S + ++L+ V Sbjct: 299 DIARQYQQRRDVLVKGLREAGWMVENPKASMYVWAKIPEPYAHLGSLEFAKKLLQDAKVS 358 Query: 424 TTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 +PG GFG G+ VR + +R+ + +A R K +++ Sbjct: 359 VSPGIGFGDYGDDHVRFALIENRDRLRQAVRGIKAMFR 396 >1GDE-A nrPDB Length = 389 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 98/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%) Query: 93 VISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYG 148 VISLGIG DT + I E A+ K G + YG G LR AIA+ Sbjct: 28 VISLGIGEPDFDTPQHIKEYAKEALDK---------GLTHYGPNIGLLELREAIAEKLKK 78 Query: 149 GLGIGDD---DVFVSDGA-KCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFN 204 GI D ++ V GA + + L + + P++ +Y + ++ G Sbjct: 79 QNGIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGK---P 135 Query: 205 TDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKK 264 +V Y E+ E + +T + SP NPTGA T++ L ++ +F + Sbjct: 136 VEVPTYEEDEFRLNVDELKKY----VTDKTRALIINSPCNPTGAVLTKKDLEEIADFVVE 191 Query: 265 NGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKL 323 + I++ D Y ++ DD SI + G E + FSK TG RLG+ P + Sbjct: 192 HDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFVAAPSWI 251 Query: 324 LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDT 383 + F TC + I A A A +A+ ++ Y ++ Sbjct: 252 IER-----MVKFQMYNATC--PVTFIQYAAAKALKDERSWKAVEEMRKEYDRRRKLVWKR 304 Query: 384 FTSLGYDVYGGKNAPYVWVHFPNQS-SWDVFAEI-LEKTHVVTTPGSGFGPGGEGFVRVS 441 +G K A Y++ + + F+E+ L++ V PGS FG GEG+VR+S Sbjct: 305 LNEMGLPTVKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAFGKAGEGYVRIS 364 Query: 442 AFGHRENILEACRRFKQLYK 461 E + EA R +++ K Sbjct: 365 YATAYEKLEEAMDRMERVLK 384 >1O4S-A nrPDB Length = 389 Score = 88.2 bits (217), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 101/376 (26%), Positives = 151/376 (40%), Gaps = 42/376 (11%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTF---YGG 149 VI+L G+ P PE + + + G Y +G LR IAK Y Sbjct: 43 VINLTAGEPDFPTPEPVVEEAVRFLQK-----GEVKYTDPRGIYELREGIAKRIGERYKK 97 Query: 150 LGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 I D V V++GAK Q +F N +A+ DP V S V + Q + Sbjct: 98 -DISPDQVVVTNGAK------QALF--NAFMALLDPGDEVIVFSPVWVSYIPQI---ILA 145 Query: 210 YGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKK 264 G + + F P L V G+T + SPNNPTG RE L LV AKK Sbjct: 146 GGTVNVVETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRREFLEGLVRLAKK 205 Query: 265 NGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 I+ D Y + D SI ++ + + FSK TG R+G+ + +K Sbjct: 206 RNFYIISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFSKSHSMTGWRVGYLISSEK-- 263 Query: 325 YSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTF 384 VA ++I + + ++Q AL L + ++ +KE N +++ Sbjct: 264 ------VATAVSKIQSHTTSCINTVAQYAALKALEVDN----SYMVQTFKERKNFVVERL 313 Query: 385 TSLGYDVYGGKNAPYVWVHFPNQSSWDVFAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAF 443 +G + A Y++ F + F E +LE+ V PGS F GFVR+S Sbjct: 314 KKMGVKFVEPEGAFYLF--FKVRGDDVKFCERLLEEKKVALVPGSAFLK--PGFVRLSFA 369 Query: 444 GHRENILEACRRFKQL 459 E + EA R + Sbjct: 370 TSIERLTEALDRIEDF 385 >2O1B-A nrPDB Length = 404 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 88/384 (22%), Positives = 151/384 (39%), Gaps = 50/384 (13%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGI 152 +I++ +G P P+ I K TI YGA G + + AI + + Sbjct: 49 LINMAVGIPDGPTPQGIIDHFQKAL----TIPENQKYGAFHGKEAFKQAIVDFYQRQYNV 104 Query: 153 ---GDDDVFVSDGAKCDISRLQV-MFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 208 +D+V + G K + + + + + DP Y Y+ + V++ Sbjct: 105 TLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYL-AGVLLAD--------- 154 Query: 209 KYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAK 263 G + P + + PD S V +T +I+ PNNPTG+ AT+E + + K Sbjct: 155 --GKPVPLNLEPPH-YLPDWSKVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFK 211 Query: 264 KNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKL 323 + IV+D AY + D SI ++VA+E S SK +G R+G+ V Sbjct: 212 GTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVGFAV----- 266 Query: 324 LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIII-- 381 N+ + + AG L + A++ F +E +N+ Sbjct: 267 -----------GNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKTR 315 Query: 382 -DTFTSL----GYDVYGGKNAPYVWVHFPNQSSWDVFAEIL-EKTHVVTTPGSGFGPGGE 435 D F ++ K YVW+ P + F + L ++ ++ PG FG G Sbjct: 316 RDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVQEKSILVAPGKPFGENGN 375 Query: 436 GFVRVSAFGHRENILEACRRFKQL 459 +VR+S + + EA R +L Sbjct: 376 RYVRISLALDDQKLDEAAIRLTEL 399 >2Z61-A nrPDB Length = 370 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 90/382 (23%), Positives = 151/382 (39%), Gaps = 40/382 (10%) Query: 83 AHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAI 142 A L+ +VI L IG+ P+ I K S EG + Y +G LR I Sbjct: 21 AQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIK-----SLKEGKTHYTDSRGILELREKI 75 Query: 143 AKTFYGGL--GIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQ 199 ++ + I D++ ++ G+ + L + + +Q+P YP Y + +G Sbjct: 76 SELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGA 135 Query: 200 TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLV 259 F ++ + E +T I SP+NP G RE + Sbjct: 136 KPVF---------CDFTVESLEEAL------SDKTKAIIINSPSNPLGEVIDRE----IY 176 Query: 260 EFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319 EFA +N I+ D Y + + S E E + FSK TG R+G+ + Sbjct: 177 EFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVIS 236 Query: 320 PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNI 379 +++ + ++ F A ISQ AL E ++ +I + + Sbjct: 237 NDEIIEA--------ILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRL 288 Query: 380 IIDTFTSLGYDVYGGKNAPYVWVHFPN--QSSWDVFAEILEKTHVVTTPGSGFGPGGEGF 437 ++ G++V A YV FPN + + ++L++ V TPG GFG G+ + Sbjct: 289 VLKYVKDFGWEVNNPIGAYYV---FPNIGEDGREFAYKLLKEKFVALTPGIGFGSKGKNY 345 Query: 438 VRVSAFGHRENILEACRRFKQL 459 +R+S ENI E R K+ Sbjct: 346 IRISYANSYENIKEGLERIKEF 367 >3JTX-A nrPDB Length = 396 Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 94/401 (23%), Positives = 163/401 (40%), Gaps = 66/401 (16%) Query: 92 QVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIA---KTFYG 148 + + L IG+ P P+VIT A+ HEL Y G LR A A K Y Sbjct: 31 EAVPLHIGEPKHPTPKVITDALTASLHELEK------YPLTAGLPELRQACANWLKRRYD 84 Query: 149 GLGI-GDDDVFVSDGAKCDI-SRLQVMF-----GSNVTIAVQDPSYPAYVDSSVIMGQTG 201 GL + D+++ G++ + S +Q + G I +P Y Y ++++ G Sbjct: 85 GLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGG--- 141 Query: 202 QFNTDVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLT 256 G I + C P F PD ++ RT ++F CSPNNP+G+ + Sbjct: 142 ---------GEIHFANC-PAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWK 191 Query: 257 QLVEFAKKNGSIIVYDSAYA-MYMSDDNP----RSIFEIPGAEEVAMETASFSKYAGFTG 311 ++ + K G II D Y+ +Y + P ++ ++ + + + S SK + G Sbjct: 192 EVFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPG 251 Query: 312 VRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGA--SNISQAGALACLTPEGLEAMHKV 369 +R G+ +LL K+F ++ ++G+ S Q ++A E V Sbjct: 252 LRSGFVAGDAELL--------KNF--LLYRTYHGSAMSIPVQRASIAAWDDE-----QHV 296 Query: 370 IG---FYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTP 426 I Y+E +I + +DV + Y+W+ P+ + +K + P Sbjct: 297 IDNRRLYQEKFERVIPILQQV-FDVKLPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLP 355 Query: 427 GSGF------GPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 G G GEG+VR++ ++A LY+ Sbjct: 356 GRFLARDTEQGNPGEGYVRIALVADVATCVKAAEDIVSLYR 396 >5YHV-A nrPDB Length = 394 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 98/396 (24%), Positives = 153/396 (38%), Gaps = 55/396 (13%) Query: 78 ARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKP 137 A R+ H +++L G + PE + +A A H L+ + GY G Sbjct: 30 AERQRTH------GDLVNLSAGQPSAGAPEPVRAAAAAALH-LNQL----GYSVALGIPE 78 Query: 138 LRAAIAKTFY--GGLGIGDDDVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSYPAYVDSS 194 LR AIA + G+ + D V ++ G+ + F + +A+ P YP Y + Sbjct: 79 LRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNIL 138 Query: 195 VIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI----IFFCSPNNPTGAAA 250 +G + + C P+ F P + D + SP NPTG Sbjct: 139 SALG------------CEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVI 186 Query: 251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFT 310 E+L + + + ++ D Y + P++ + A+ SFSKY T Sbjct: 187 PPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRN-AVVVNSFSKYYAMT 245 Query: 311 GVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNI-----SQAGALACLTPEGLEA 365 G RLGW ++P L R C G I SQ A++ TPE Sbjct: 246 GWRLGWLLVPTVL-------------RRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAE 292 Query: 366 MHKVIGFYKENTNIIIDTFTSLGYDVYGGKN-APYVWVHFPNQSSWDVFA---EILEKTH 421 + Y N ++++D +G D + A YV+ + +S D A ++L T Sbjct: 293 ADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTS-DSLAFCSKLLADTG 351 Query: 422 VVTTPGSGFGPG-GEGFVRVSAFGHRENILEACRRF 456 V PG F G FVR+S G +I EA RR Sbjct: 352 VAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRI 387 >1GC4-A nrPDB Length = 385 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 95/390 (24%), Positives = 158/390 (40%), Gaps = 50/390 (12%) Query: 86 LKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKT 145 L+ +++L G+ P+ T K+A + +G + Y G LR A+A+ Sbjct: 26 LRRQGVDLVALTAGE-----PDFDTPEHVKEAARRALAQGKTKYAPPAGIPELREALAEK 80 Query: 146 FY--GGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQF 203 F GL + ++ V+ G Q +F N+ A+ DP D +++ Sbjct: 81 FRRENGLSVTPEETIVTVGGS------QALF--NLFQAILDPG-----DEVIVLSPYWVS 127 Query: 204 NTDVQKY--GNIEYMRCTPENGFFPDLSTVGR-----TDIIFFCSPNNPTGAAATREQLT 256 ++ ++ G + + PE GF PD V R T + SPNNPTGA +E L Sbjct: 128 YPEMVRFAGGVVVEVETLPEEGFVPDPERVRRAITPRTKALVVNSPNNPTGAVYPKEVLE 187 Query: 257 QLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG--AEEVAMETASFSKYAGFTGVRL 314 L A ++ +V D Y + + S PG A E + +K TG R+ Sbjct: 188 ALARLAVEHDFYLVSDEIYEHLLYEGEHFS----PGRVAPEHTLTVNGAAKAFAMTGWRI 243 Query: 315 GWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGF-- 372 G+ PK+++ K + I+Q L LT + EA + Sbjct: 244 GYACGPKEVI--------KAMASVSRQSTTSPDTIAQWATLEALTNQ--EASRAFVEMAR 293 Query: 373 --YKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDV-FAEILEKTHVVTTPGSG 429 Y+ +++++ T+LG A YV + + +V AE L + V PG+ Sbjct: 294 EAYRRRRDLLLEGLTALGLKAVRPSGAFYVLMDTSPIAPDEVRAAERLLEAGVAVVPGTD 353 Query: 430 FGPGGEGFVRVSAFGHRENILEACRRFKQL 459 F G VR+S EN+ +A RF ++ Sbjct: 354 F--AAFGHVRLSYATSEENLRKALERFARV 381 >1V2E-A nrPDB Length = 381 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 79/344 (22%), Positives = 135/344 (39%), Gaps = 42/344 (12%) Query: 94 ISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG 153 ++LG G + P P + A+ + + Y G LR A+A+ F + Sbjct: 28 VNLGQGFPSNPPPPFLLEAVRR------ALGRQDQYAPPAGLPALREALAEEF----AVE 77 Query: 154 DDDVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGN 212 + V V+ GA + LQ + G + V +P + Y+ + + G + Sbjct: 78 PESVVVTSGATEALYVLLQSLVGPGDEVVVLEPFFDVYLPDAFLAGAKAR---------- 127 Query: 213 IEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGS 267 + + TPE GF DLS + RT + +P NPTG +L + A+ + Sbjct: 128 LVRLDLTPE-GFRLDLSALEKALTPRTRALLLNTPMNPTGLVFGERELEAIARLARAHDL 186 Query: 268 IIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD 327 ++ D Y + PR + E A E S K TG R+GW V PK+ + Sbjct: 187 FLISDEVYDELYYGERPRRLREF--APERTFTVGSAGKRLEATGYRVGWIVGPKEFM--- 241 Query: 328 GFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGF-YKENTNIIIDTFTS 386 P + T F+ + + QAG L E ++ + Y+ +++ + Sbjct: 242 --PRLAGMRQ--WTSFSAPTPL-QAGVAEALKLARREGFYEALREGYRRRRDLLAGGLRA 296 Query: 387 LGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGF 430 +G VY + ++ P WD F ++E+ V P S F Sbjct: 297 MGLRVYVPEGTYFLMAELPG---WDAF-RLVEEARVALIPASAF 336 >1XI9-A nrPDB Length = 406 Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 109/398 (27%), Positives = 168/398 (42%), Gaps = 63/398 (15%) Query: 92 QVISLGIGDTT----EPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAK--T 145 +VI L IGD +P PE + A K + EG++ YG +G LR AI + Sbjct: 39 KVIRLNIGDPVKFDFQP-PEHMKEAYCK-----AIKEGHNYYGDSEGLPELRKAIVEREK 92 Query: 146 FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNV----TIAVQDPSYPAYVDSSVIMGQTG 201 G+ I DDV V+ LQ++FG+ + I V PSYP Y TG Sbjct: 93 RKNGVDITPDDVRVTAAV---TEALQLIFGALLDPGDEILVPGPSYPPY---------TG 140 Query: 202 QFNTDVQKYGN--IEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQ 254 V+ YG +EY R E + PD+ + RT I +PNNPTGA ++ Sbjct: 141 L----VKFYGGKPVEY-RTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYDKKT 195 Query: 255 LTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA---EEVAMETASFSKYAGFTG 311 L +++ A + ++ D Y + + S PG+ + + SK TG Sbjct: 196 LEEILNIAGEYEIPVISDEIYDLMTYEGEHIS----PGSLTKDVPVIVMNGLSKVYFATG 251 Query: 312 VRLGWT--VIPKKLLYSDGFPVAKDFNRI--ICTCFNGASNISQAGALACLTPEGLEAMH 367 RLG+ V P+ L V + +R+ I C N + Q A+A LT ++ + Sbjct: 252 WRLGYMYFVDPENKLSE----VREAIDRLARIRLCPNTPA---QFAAIAGLT-GPMDYLK 303 Query: 368 KVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWVHF---PNQSSWDVFAEILEKTHVV 423 + + KE + I + G + A Y++ P ++ + ++L HV+ Sbjct: 304 EYMKKLKERRDYIYKRLNEIPGISTTKPQGAFYIFPKIEVGPWKNDKEFVLDVLHNAHVL 363 Query: 424 TTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 GSGFG G G R E + EA RF++ K Sbjct: 364 FVHGSGFGEYGAGHFRAVFLPPIEILEEAMDRFEKFMK 401 >4MY5-A nrPDB Length = 393 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 93/404 (23%), Positives = 163/404 (40%), Gaps = 32/404 (7%) Query: 62 NSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELS 121 N N++K++ + R+ + PD V+ L +G+ P+ I A AK+A + Sbjct: 10 NKNLNKIEVSMI-----RQFDQSISDIPD--VLKLTLGEPDFATPKHIKEA-AKRAIDAD 61 Query: 122 TIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTI 180 Y+G + +A K Y D+++ V+ GA +S L + + Sbjct: 62 E-SHYTGMAGLLALRQAASAFVKEKYHLTYNPDNEILVTIGATEALSASLTAILEPGDKV 120 Query: 181 AVQDPSYPAYVDSSVIMG-QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFF 239 + P+YP Y ++G + + +T + TPE L + Sbjct: 121 LLPAPAYPGYEPVVNLVGAEVVEIDTRSNDF------VLTPEMLEEAILKEGEALKAVIL 174 Query: 240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAM 298 P NPTG +R+Q+ L E KK ++ D YA + + ++ SI E + + + Sbjct: 175 NYPTNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYAELTYTGESHVSIAEYLPDQTILI 234 Query: 299 ETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACL 358 + SK TG RLG P L + K ++ A+ Q A+ L Sbjct: 235 --SGLSKSHAMTGWRLGLIFAPAVLTAQ----LIKSHQYLVT----AATTSVQFAAIEAL 284 Query: 359 TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP---NQSSWDVFAE 415 T G + + Y + + II+ ++ + + A Y++ P Q S+ + Sbjct: 285 T-NGKDDALPMKEEYIKRRDYIIEKMEAMKFKIIKPDGAFYIFAKIPVAQGQDSFKFLQD 343 Query: 416 ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 ++ V PG FG GEG++R+S E I EA +R K+ Sbjct: 344 FAKEKAVAFIPGVAFGKYGEGYLRISYAASMETIKEAMKRLKEF 387 >1J32-A nrPDB Length = 388 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 95/392 (24%), Positives = 165/392 (42%), Gaps = 45/392 (11%) Query: 83 AHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAI 142 A +K V S G+ P+ I A AK A E +G + YG G LR AI Sbjct: 22 AKAMKAEGIDVCSFSAGEPDFNTPKHIVEA-AKAALE----QGKTRYGPAAGEPRLREAI 76 Query: 143 AKTFY--GGLGIGDDDVFVSDGAKCDISRLQV-MFGSNVTIAVQDP---SYPAYVD---- 192 A+ GL G D++ V++G K I L + M + + P SYP V Sbjct: 77 AQKLQRDNGLCYGADNILVTNGGKQSIFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLAEG 136 Query: 193 SSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATR 252 + VI+ T + Q + E +R + +T ++ F +P+NPTG T Sbjct: 137 TPVILPTT----VETQFKVSPEQIR----------QAITPKTKLLVFNTPSNPTGMVYTP 182 Query: 253 EQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR-SIFEI-PGAEEVAMETASFSKYAGFT 310 +++ + + A + G ++ D Y + DD SI P A E ++ + F+K T Sbjct: 183 DEVRAIAQVAVEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSVVCSGFAKTYAMT 242 Query: 311 GVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVI 370 G R+G+ P P+ K +I + +Q GA+A + + +++ Sbjct: 243 GWRVGFLAGP--------VPLVKAATKIQGHSTSNVCTFAQYGAIAAYE-NSQDCVQEML 293 Query: 371 GFYKENTNIIIDTFTSL-GYDVYGGKNAPYVW--VHFPNQSSWDVFAEILEKTHVVTTPG 427 + E ++D ++ G + A Y++ + +SS D +E+L++ V T PG Sbjct: 294 AAFAERRRYMLDALNAMPGLECPKPDGAFYMFPSIAKTGRSSLDFCSELLDQHQVATVPG 353 Query: 428 SGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 + F G + +R+S + I R ++ Sbjct: 354 AAF--GADDCIRLSYATDLDTIKRGMERLEKF 383 >3H14-A nrPDB Length = 391 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 90/379 (23%), Positives = 145/379 (38%), Gaps = 39/379 (10%) Query: 92 QVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTF--YGG 149 ++I + +G P A+AK + GY G LR IA+ + + G Sbjct: 32 RIIHMEVGQPGTGAPRGAVEALAKSLETDAL-----GYTVALGLPALRQRIARLYGEWYG 86 Query: 150 LGIGDDDVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 208 + + V ++ G+ + +F S + + P YP+Y I+ G D+ Sbjct: 87 VDLDPGRVVITPGSSGGFLLAFTALFDSGDRVGIGAPGYPSY---RQILRALGLVPVDLP 143 Query: 209 KYGNIEYMRCTPENGFFPDLSTVGRTDI--IFFCSPNNPTGAAATREQLTQLVEFAKKNG 266 PEN P + D+ + SP NPTG + L+E A+ G Sbjct: 144 ---------TAPENRLQPVPADFAGLDLAGLMVASPANPTGTMLDHAAMGALIEAAQAQG 194 Query: 267 SIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYS 326 + + D Y + + E+ + SFSKY TG R+GW V+P+ Sbjct: 195 ASFISDEIYHGIEYEAKAVTALEL---TDECYVINSFSKYFSMTGWRVGWMVVPE----- 246 Query: 327 DGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTS 386 D V + + + C AS ++ AL C + + YK N ++++ Sbjct: 247 DQVRVVERIAQNMFICAPHASQVAALAALDCDA-----ELQANLDVYKANRKLMLERLPK 301 Query: 387 LGYD-VYGGKNAPYVWVHFPN--QSSWDVFAEILEKTHVVTTPGSGFGPG-GEGFVRVSA 442 G+ + A YV+ + S AEILEK V TPG F P G G +R S Sbjct: 302 AGFTRIAPPDGAFYVYADVSDLTDDSRAFAAEILEKAGVAVTPGLDFDPERGAGTLRFSY 361 Query: 443 FGHRENILEACRRFKQLYK 461 +I E R + + Sbjct: 362 ARATADIEEGLDRLEAFMQ 380 >4CVQ-A nrPDB Length = 431 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 55/207 (26%), Positives = 93/207 (44%), Gaps = 24/207 (11%) Query: 127 SGYGAEQGAKPLRAAIAKTFYGGLGIGD---DDVFVSDG-AKCDISRLQVMFGSNVTIAV 182 GY +G R AI + Y G+ D +D+++ +G ++ + +Q + S + V Sbjct: 92 QGYCDSKGLYSARKAIMQ-HYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLV 150 Query: 183 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDII 237 P YP + ++ + +G+ + Y+ C + +FPDL + RT I Sbjct: 151 PAPDYPLW--TAAVSLSSGK---------AVHYL-CDESSDWFPDLDDIRAKITPRTRGI 198 Query: 238 FFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVA 297 +PNNPTGA ++E L ++VE A+++ II D Y + DD + + Sbjct: 199 VIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLT 258 Query: 298 METASFSKYAGFTGVRLGWTVI--PKK 322 + SK G R GW V+ PKK Sbjct: 259 ITFNGLSKTYRVAGFRQGWMVLNGPKK 285 >2DOU-A nrPDB Length = 376 Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 88/371 (23%), Positives = 159/371 (42%), Gaps = 29/371 (7%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGI 152 +I L IG T P PE A+A+ ++ +T GY + P A+ + G G+ Sbjct: 27 LIDLSIGSTDLPPPEAPLKALAEALNDPTTY----GYCLKSCTLPFLEEAARWYEGRYGV 82 Query: 153 GDD---DVFVSDGAKCDISRLQVMFGS-NVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 208 G D + G++ ++ L + + + + +YP+Y ++ + F ++ Sbjct: 83 GLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSYFGAARV-ASLRTFLIPLR 141 Query: 209 KYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSI 268 + G + ++ PE + ++ PNNPTGA A + + A+K+G Sbjct: 142 EDG-LADLKAVPEGVW-------REAKVLLLNYPNNPTGAVADWGYFEEALGLARKHGLW 193 Query: 269 IVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDG 328 +++D+ Y + + S +PGA+E +E S SK G RLG+ + ++ L Sbjct: 194 LIHDNPYVDQVYEGEAPSPLALPGAKERVVELFSLSKSYNLAGFRLGFALGSEEAL---- 249 Query: 329 FPVAKDFNRIICTC-FNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL 387 R+ FN + + + G A TP+ E + Y+E + + + Sbjct: 250 ----ARLERVKGVIDFNQYAGVLRMGVEALKTPK--EVVRGYARVYRERALGMAEALKGV 303 Query: 388 GYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRE 447 + + Y+W P F L + V PG GFGPGG+GFVR++ E Sbjct: 304 -LSLLPPRATMYLWGRLPEGVDDLEFGLRLVERGVALAPGRGFGPGGKGFVRIALVRPLE 362 Query: 448 NILEACRRFKQ 458 +LEA +R ++ Sbjct: 363 ELLEAAKRIRE 373 >3ELE-A nrPDB Length = 398 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 90/412 (21%), Positives = 163/412 (39%), Gaps = 66/412 (16%) Query: 76 EIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGA 135 E ++R+A + K V IG+ + P P+++ + + + ++ GY + QG Sbjct: 23 EYGKKRAAIVGK---ENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSV-ALHGYTSAQGD 78 Query: 136 KPLRAAIAKTFYG--GLGIGDDDVFVSDGAKCDISRLQVMFGSN-----VTIAVQDPSYP 188 RAAIA+ G D+++++ GA +S S+ +TIA P Y Sbjct: 79 VETRAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYK 138 Query: 189 AYVDSS-----VIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPN 243 +V+++ + T F D + T + SPN Sbjct: 139 VFVNAAGARLVEVPADTEHFQIDFDAL----------------EERINAHTRGVIINSPN 182 Query: 244 NPTGAAATREQLTQLVEFAKKNGS------IIVYDSAYAMYMSDDNPRSIFEIPGAEEVA 297 NP+G + E + +L + +K I+ D Y + D ++P + Sbjct: 183 NPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDG-----IKVPFVTKYY 237 Query: 298 META---SFSKYAGFTGVRLGWTVIPKKL-----LYSDGFPVAKDFNRIICTCFNGASNI 349 T S+SK G R+G+ ++P ++ LY+ + + A ++ Sbjct: 238 DNTLVCYSYSKSLSLPGERIGYVLVPDEVYDKAELYAAVCGAGRALGYVC------APSL 291 Query: 350 SQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSS 409 Q + C G I YKEN +++ + T +GY + A Y++V S Sbjct: 292 FQKMIVKCQGATG------DINAYKENRDLLYEGLTRIGYHCFKPDGAFYMFVKALEDDS 345 Query: 410 WDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 + F E ++ V+ GF G G+VR+S RE I + F+++YK Sbjct: 346 -NAFCEKAKEEDVLIVAADGF--GCPGWVRISYCVDREMIKHSMPAFEKIYK 394 >5WMH-A nrPDB Length = 475 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 88/392 (22%), Positives = 157/392 (40%), Gaps = 65/392 (16%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFY--GGL 150 VI L G+ P+V+ A E G++ Y G LR AI + GL Sbjct: 101 VIRLAAGEPDFDTPKVVAEAGINAIRE-----GFTRYTLNAGITELREAICRKLKEENGL 155 Query: 151 GIGDDDVFVSDGAKCDISRLQVMF-----GSNVTIAVQDPSYPAYVDSSVIMGQTGQFNT 205 D + VS+GAK S LQ + G V I P + +Y + + + T Sbjct: 156 SYAPDQILVSNGAKQ--SLLQAVLAVCSPGDEVIIPA--PYWVSYTEQARLADATPVV-- 209 Query: 206 DVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVE 260 + N F D + ++ ++ CSP+NPTG+ + L ++ Sbjct: 210 ----------IPTKISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIAR 259 Query: 261 FAKKNGSIIVY-DSAYAMYMSDDNPRSIF-EIPGAEEVAMETASFSKYAGFTGVRLGWTV 318 K+ ++V D Y + + F +P E + FSK TG RLG+ Sbjct: 260 IIAKHPRLLVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLA 319 Query: 319 IPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC--LTPEGLEAMHKVIGFYKEN 376 PK ++ + +++ +GAS+I+Q +A L G E + +++ Y+E Sbjct: 320 GPKHIVAA--------CSKLQGQVSSGASSIAQKAGVAALGLGKAGGETVAEMVKAYRER 371 Query: 377 TNIIIDTFTSL-GYDVYGGKNAPYVWVHFP--------------NQSSWDVFAEILEKTH 421 + ++ + + G + + A Y+++ F + SS ++ L+K Sbjct: 372 RDFLVKSLGDIKGVKISEPQGAFYLFIDFSAYYGSEAEGFGLINDSSSLALY--FLDKFQ 429 Query: 422 VVTTPGSGFGPGGEGFVRVSAFGHRENILEAC 453 V PG F G + +R+S + ++L+A Sbjct: 430 VAMVPGDAF--GDDSCIRIS-YATSLDVLQAA 458 >1U08-A nrPDB Length = 386 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 77/366 (21%), Positives = 144/366 (39%), Gaps = 51/366 (13%) Query: 115 KKAHELSTIEGYSGYGAEQGAKPLRAAIAKT---FYGGLGIGDDDVFVSDGA-KCDISRL 170 + AH ++ +G + Y G + LR AIA+ YG D D+ V+ GA + + + Sbjct: 51 RLAHHVA--QGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATEALYAAI 108 Query: 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMG--------QTGQFNTDVQKYGNIEYMRCTPEN 222 + + + DPSY +Y + + G Q F D Q++ + Sbjct: 109 TALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAAL--------- 159 Query: 223 GFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSD 281 LS RT ++ +P+NP+ + L + + ++ D Y + S Sbjct: 160 -----LSE--RTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQ 212 Query: 282 DNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRI--- 338 S+ P E A+ +SF K TG ++G+ V P P++ + ++ Sbjct: 213 QGHASVLAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPA--------PISAEIRKVHQY 264 Query: 339 ICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAP 398 + N + ++ A L PE A+ FY++ +I+++ ++ + Sbjct: 265 LTFSVNTPAQLALADMLRA-EPEHYLALPD---FYRQKRDILVNALNESRLEILPCEGTY 320 Query: 399 YVWVHFPNQSSWD--VFAEILEKTH-VVTTPGSGF--GPGGEGFVRVSAFGHRENILEAC 453 ++ V + S+ D F + L + H V P S F P +R+ +L A Sbjct: 321 FLLVDYSAVSTLDDVEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAA 380 Query: 454 RRFKQL 459 R +QL Sbjct: 381 ERLRQL 386 >3EZS-A nrPDB Length = 376 Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 87/369 (23%), Positives = 144/369 (39%), Gaps = 52/369 (14%) Query: 89 PDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYG 148 P + + LGIG+ P+ I A+ H L+ Y + LRAA F Sbjct: 21 PKKRGLDLGIGEPQFETPKFIQDALKNHTHSLNI------YPKSAFEESLRAAQRGFFKR 74 Query: 149 GLGI--GDDDVFVSDGAKCDISRLQ--VMFG-SNVTIAVQDPSYPAYVDSSVIMGQTGQF 203 I ++++ + G++ + V+F N TIA +P Y Y ++ + Sbjct: 75 RFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSLL 134 Query: 204 NTDVQKYGNIEYMRCTPENGFFPDLST--VGRTDIIFFCSPNNPTGAAATREQLTQLVEF 261 M T EN F P L+ + D++ SPNNPTG + E+L V+ Sbjct: 135 ------------MPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELISWVKL 182 Query: 262 AKKNGSIIVYDSAYAMYMSDDNPRSIFE---IPGAEEV--AMETASFSKYAGFTGVRLGW 316 A K+ I++ D Y+ + P S+ E + G E + S SK + G+R G+ Sbjct: 183 ALKHDFILINDECYSEIYENTPPPSLLEACMLAGNEAFKNVLVIHSLSKRSSAPGLRSGF 242 Query: 317 TVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKEN 376 +LL K F + + A+ I +A A L E + Y N Sbjct: 243 IAGDSRLLEK-----YKAFRAYL--GYTSANAIQKASEAAWLDDRHAEFFRNI---YANN 292 Query: 377 TNIIIDTF-TSLGYDVYGGKNAPY-VWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPG- 433 + F +L Y PY +V+ P Q+ + + + ++T P G Sbjct: 293 LKLARKIFKNTLIY--------PYSFYVYLPVQNGENFAKTLYQNEGIITLPALYLGRNR 344 Query: 434 -GEGFVRVS 441 G +VR++ Sbjct: 345 IGADYVRLA 353 >6F77-B nrPDB Length = 400 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 100/412 (24%), Positives = 159/412 (38%), Gaps = 62/412 (15%) Query: 77 IARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAK 136 IA + A LK VI LG G+ P+ T KKA + G + Y G Sbjct: 17 IAVSQKARELKAKGRDVIGLGAGE-----PDFDTPDNIKKAAIDAIDRGETKYTPVSGIP 71 Query: 137 PLRAAIAKTFY--GGLGIGDDDVFVSDGAKCDISRLQVMFGSNVT-------IAVQDPSY 187 LR AIAK F L V G K Q++F + + + + P + Sbjct: 72 ELREAIAKKFKRENNLDYTAAQTIVGTGGK------QILFNAFMATLNPGDEVVIPAPYW 125 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTG 247 +Y + + G T F Q+ + E+ D + +T F SP+NP+G Sbjct: 126 VSYPEMVALCGGTPVFVPTRQE----NNFKLKAED---LDRAITPKTKWFVFNSPSNPSG 178 Query: 248 AAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI---PGAEEVAMETASFS 304 AA + E+L L + K+ + V +++ + R + PG E + S Sbjct: 179 AAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVS 238 Query: 305 KYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT-PEGL 363 K TG R+G+ P L+ K + I +GA++I+Q A+ L P+ Sbjct: 239 KAYAMTGWRIGYAAGPLHLI--------KAMDMIQGQQTSGAASIAQWAAVEALNGPQDF 290 Query: 364 EAMHKVIGFYKENTNIIIDTFTSL----------GYDVYG------GKNAPYVWVHFPNQ 407 +K I ++ ++++ + VY GK AP V + Sbjct: 291 IGRNKEI--FQGRRDLVVSMLNQAKGISCPTPEGAFYVYPSCAGLIGKTAPSGKVI---E 345 Query: 408 SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 + D +E+LE V GS FG G R+S + EACRR ++ Sbjct: 346 TDEDFVSELLETEGVAVVHGSAFGLGPN--FRISYATSEALLEEACRRIQRF 395 >3OP7-A nrPDB Length = 375 Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 65/261 (24%), Positives = 115/261 (44%), Gaps = 28/261 (10%) Query: 211 GNIEYMRCTPENGFFPDLSTVGR-----TDIIFFCSPNNPTGAAATREQLTQLVEFAKKN 265 ++ + ENG+ PDL + + T +I + NNPTGA R L +LVE A + Sbjct: 127 AEVDLWQIEEENGWLPDLEKLRQLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEV 186 Query: 266 GSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLY 325 G+ I+ D Y + D P SI E+ + + S SK G+R+GW ++ Sbjct: 187 GAYILSDEVYRSFSELDVP-SIIEV---YDKGIAVNSLSKTYSLPGIRIGWVAANHQV-- 240 Query: 326 SDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNII---ID 382 +D +D+ I F+ ++ ALA E LE ++ +EN I+ I+ Sbjct: 241 TDILRDYRDYTMICAGVFD---DLVAQLALAHYQ-EILERNRHIL---EENLAILDQWIE 293 Query: 383 TFTSLGYDVYGGKNAPYV--WVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRV 440 + Y + +V V P + D ++L++ V+ PG+ F +G+VR+ Sbjct: 294 EEPLVSYIRPAVVSTSFVKIAVDMPME---DFCLQLLQEHGVLLVPGNRF--ERDGYVRL 348 Query: 441 SAFGHRENILEACRRFKQLYK 461 +E +++ + Q + Sbjct: 349 GFACEQETLIKGLEKLSQFLR 369 >6F35-A nrPDB Length = 410 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 93/402 (23%), Positives = 156/402 (38%), Gaps = 60/402 (14%) Query: 83 AHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAI 142 A +K VI LG G+ PE + A + H G + Y A G L+ AI Sbjct: 33 AAAMKREGKPVIILGAGEPDFDTPEHVKQAASDAIHR-----GETKYTALDGTPELKKAI 87 Query: 143 AKTFY--GGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQT 200 + F GL D++ V+ GAK Q++F N +A DP D +I Sbjct: 88 REKFQRENGLAYELDEITVATGAK------QILF--NAMMASLDPG-----DEVIIPTPY 134 Query: 201 GQFNTDVQKY--GNIEYMRCTPENGFFP-----DLSTVGRTDIIFFCSPNNPTGAAATRE 253 +D+ G + C +GF + + RT + SP+NP+GAA + Sbjct: 135 WTSYSDIVHICEGKPVLIACDASSGFRLTAEKLEAAITPRTRWVLLNSPSNPSGAAYSAA 194 Query: 254 QLTQLVEFAKKNGSI-IVYDSAYAMYMSDD----NPRSIFEIPGAEEVAMETASFSKYAG 308 L+E ++ + ++ D Y + D P + PG + + SK Sbjct: 195 DYRPLLEVLLRHPHVWLLVDDMYEHIVYDGFRFVTPAQLE--PGLKNRTLTVNGVSKAYA 252 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT-PEGLEAMH 367 TG R+G+ P++L+ K + + S+ISQA ++ L P+ + Sbjct: 253 MTGWRIGYAGGPRELI--------KAMAVVQSQATSCPSSISQAASVVALNGPQDF--LK 302 Query: 368 KVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWVHFPN------------QSSWDVFA 414 + ++ +++++ ++ G D + A Y + ++ D A Sbjct: 303 ERTESFQRRRDLVVNGLNAIDGLDCRVPEGAFYTFSGCAGVLGKVTPSGKRIKTDTDFCA 362 Query: 415 EILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRF 456 +LE HV PGS FG F R+S + EA R Sbjct: 363 YLLEDAHVAVVPGSAFGLS--PFFRISYATSEAELKEALERI 402 >3DYD-A nrPDB Length = 427 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 94/395 (23%), Positives = 149/395 (37%), Gaps = 52/395 (13%) Query: 89 PDAQVISLGIGDTTE----PIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAK 144 P+ +ISL IGD T P +T AM K A + Y+GY G R IA Sbjct: 52 PNKTMISLSIGDPTVFGNLPTDPEVTQAM-KDALDSGK---YNGYAPSIGFLSSREEIAS 107 Query: 145 TFYGGLG-IGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQ 202 ++ + DV ++ G I L V+ I V P + Y + MG Sbjct: 108 YYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMG---- 163 Query: 203 FNTDVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQ 257 +V+ Y + PE + DL + +T + +P+NP G+ ++ L + Sbjct: 164 --IEVKLYNLL------PEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQK 215 Query: 258 LVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWT 317 ++ A + I+ D Y + D + + +K G RLGW Sbjct: 216 ILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWI 275 Query: 318 VIPKKL-----LYSDGFPVAKDFNRII--CTCFNGASNISQAGALACLTPEGLEAMHKVI 370 +I + DG + K RI+ CT GA ++ C TP E H + Sbjct: 276 LIHDRRDIFGNEIRDG--LVKLSQRILGPCTIVQGALK-----SILCRTPG--EFYHNTL 326 Query: 371 GFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWV-----HFPNQSSWDVFAE-ILEKTHVV 423 F K N ++ ++ G A Y+ V HFP + F E ++ + V Sbjct: 327 SFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVH 386 Query: 424 TTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 P + F F+RV +LEAC R ++ Sbjct: 387 CLPATCF--EYPNFIRVVITVPEVMMLEACSRIQE 419 >4M2J-A nrPDB Length = 406 Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 60/214 (28%), Positives = 93/214 (43%), Gaps = 42/214 (19%) Query: 133 QGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSY---- 187 QG + +R AIA + GG D V V+ G+ I+ L + + VQ+ Y Sbjct: 84 QGGEGVRRAIADRYAGG---DADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLG 140 Query: 188 ----PAYVDSSVIMGQT---GQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFC 240 A D +V+ G+ G+ + DV L T G T + Sbjct: 141 HYPRAAGCDVAVLPGRAVRDGEIDPDV-----------------LAGLVTPG-TAAVIVN 182 Query: 241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET 300 P+NPTG + + L L E G+++V+D+A A + + PGA+ +T Sbjct: 183 FPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIA---HRWEVLADPGAD--GGDT 237 Query: 301 ASF---SKYAGFTGVRLGWTVIPKKLLYSDGFPV 331 S+ SK G G+R+GW V PK+LL + FP+ Sbjct: 238 VSYGTLSKTFGLPGLRVGWAVAPKELLTAT-FPL 270 >2ZC0-A nrPDB Length = 407 Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 104/404 (25%), Positives = 169/404 (41%), Gaps = 48/404 (11%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSA-MAKKAHELSTIEGYS-GYGAEQGAKPL 138 + A L+ ++ISL GD P PE+I A + + A E+ E S Y G L Sbjct: 24 KKASELQKKGVKLISLAAGD---PDPELIPRAVLGEIAKEVLEKEPKSVMYTPANGIPEL 80 Query: 139 RAAIAKTF--YGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSV 195 R +A Y L + +++ ++ G + L +V+ + ++PSY +++ + Sbjct: 81 REELAAFLKKYDHLEVSPENIVITIGGTGALDLLGRVLIDPGDVVITENPSY---INTLL 137 Query: 196 IMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP--NNPTGAAATRE 253 Q G V + + MR +L G+ + + P NP G + E Sbjct: 138 AFEQLGAKIEGVPV--DNDGMRVDLLEEKIKELKAKGQKVKLIYTIPTGQNPMGVTMSME 195 Query: 254 QLTQLVEFAKKNGSIIVYDSAYAMYM---SDDNPRSIFEIPGAEEVAMETASFSKYAGFT 310 + L+E A K +I+ D+AY D P + G VA + SK G T Sbjct: 196 RRKALLEIASKYDLLIIEDTAYNFMRYEGGDIVPLKALDNEGRVIVA---GTLSKVLG-T 251 Query: 311 GVRLGWTV----IPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 G R+GW + I KK+L P+ DF C A ISQ AL L E Sbjct: 252 GFRIGWIIAEGEILKKVLMQKQ-PI--DF----C-----APAISQYIALEYLKRGYFEKY 299 Query: 367 H---KVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHF--PNQSSWDVFA-EILEKT 420 H ++G YKE +I++ + + K ++V F P + FA E++E+ Sbjct: 300 HLEGALLG-YKEKRDIMLKALENHLPNAEFTKPIAGMFVMFFLPEGADGISFANELMERE 358 Query: 421 HVVTTPGSGF--GPGGEGFVRVS-AFGHRENILEACRRFKQLYK 461 VV PG F G+ +R++ + +E I ++ +LYK Sbjct: 359 GVVVVPGKPFYTDESGKNAIRLNFSRPSKEEIPIGIKKLAKLYK 402 >3AV7-A nrPDB Length = 448 Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 69/315 (21%), Positives = 114/315 (36%), Gaps = 32/315 (10%) Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIG-DDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPS 186 YG +G PLR + K GI D+D+ ++ G++ + + +V + V+ P+ Sbjct: 114 YGTTKGFTPLRETLMKWLGKRYGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPT 173 Query: 187 YPAYVDSSVIMGQTGQFNTDVQKYGNI----EYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 Y A + + FN +Y I E M+ +L + G+ + + P Sbjct: 174 YLAALQA---------FNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVP 224 Query: 243 --NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET 300 NP G ++ L+E A + I+V D Y NP + E + Sbjct: 225 TFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYL 284 Query: 301 ASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNG--ASNISQAGALACL 358 +FSK G R+GW V ++ +AK + F A G L Sbjct: 285 GTFSKILA-PGFRIGWMVGDPGIIRK--MEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKH 341 Query: 359 TPEGLEAMHKVIGFYKENTNIIIDT---FTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAE 415 PE + FYK + +++ F G + ++WV P+ E Sbjct: 342 IPE-------IRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLE 394 Query: 416 ILEKTHVVTTPGSGF 430 K V PG F Sbjct: 395 RAIKKGVAYVPGEAF 409 >1X0M-A nrPDB Length = 403 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 69/315 (21%), Positives = 114/315 (36%), Gaps = 32/315 (10%) Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIG-DDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPS 186 YG +G PLR + K GI D+D+ ++ G++ + + +V + V+ P+ Sbjct: 69 YGTTKGFTPLRETLMKWLGKRYGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPT 128 Query: 187 YPAYVDSSVIMGQTGQFNTDVQKYGNI----EYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 Y A + + FN +Y I E M+ +L + G+ + + P Sbjct: 129 YLAALQA---------FNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVP 179 Query: 243 --NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET 300 NP G ++ L+E A + I+V D Y NP + E + Sbjct: 180 TFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYL 239 Query: 301 ASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNG--ASNISQAGALACL 358 +FSK G R+GW V ++ +AK + F A G L Sbjct: 240 GTFSKILA-PGFRIGWMVGDPGIIRK--MEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKH 296 Query: 359 TPEGLEAMHKVIGFYKENTNIIIDT---FTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAE 415 PE + FYK + +++ F G + ++WV P+ E Sbjct: 297 IPE-------IRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLE 349 Query: 416 ILEKTHVVTTPGSGF 430 K V PG F Sbjct: 350 RAIKKGVAYVPGEAF 364 >3T32-A nrPDB Length = 383 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 88/414 (21%), Positives = 158/414 (38%), Gaps = 60/414 (14%) Query: 73 LFPEIARRRSAHLLK---YPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGY 129 LF + RR H +K Y + ++I I D +P+ I +A+ K+ I GY+ Sbjct: 3 LFHKTVNRRGTHSIKWDTYKNEELIHAWIADMDFEVPQPIQTALKKRIEH--PIFGYTLP 60 Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYP 188 G + K Y I + + S G +S +Q N ++ VQ P YP Sbjct: 61 PENIGD--IICNWTKKQYNW-DIQKEWIVFSAGIVPALSTSIQAFTKENESVLVQPPIYP 117 Query: 189 AYVDSSVIMGQTGQFNTDVQKYGN-----IEYMRCTPENGFFPDLSTVGRTDIIFFCSPN 243 + + V + +QK + E++ + G ++ CSP+ Sbjct: 118 PFFEM-VTTNNRQLCVSPLQKQNDTYAIDFEHLEKQFQQG----------VKLMLLCSPH 166 Query: 244 NPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASF 303 NP G +E+LT+L K I+V D ++ + D+ + F +EE+A T + Sbjct: 167 NPIGRVWKKEELTKLGSLCTKYNVIVVADEIHSDIIYADHTHTPFA-SLSEELAARTITC 225 Query: 304 ---SKYAGFTGVRLGWTVIPKKLL--------YSDGFPVAKDFNRIICTCFNGASNISQA 352 SK G++ +IP + L Y GF NI Sbjct: 226 MAPSKTFNIAGLQASIIIIPNEKLRQAFTSIQYRQGF---------------HGLNIFAY 270 Query: 353 GALACLTPEGLEAMHKVIGFYKENTNI----IIDTFTSLGYDVYGGKNAPYVWVHFP--N 406 A+ E + ++++ + ++N I D +L V + + +W+ N Sbjct: 271 TAMQSAYTECNDWLNEIRFYIEDNAKFACEYIKDHIPTLS--VMKPEGSFLLWIDCSALN 328 Query: 407 QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 S + + EK ++ PG +G GGE + ++ R + E R + + Sbjct: 329 LSQDERTKLLEEKGKIIVEPGEKYGLGGEEHIGINIGCPRSVLEEILNRLRHTF 382 >1BW0-A nrPDB Length = 416 Score = 52.8 bits (125), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 58/254 (22%), Positives = 97/254 (38%), Gaps = 38/254 (14%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLG- 151 +I L +GD T + ++A KK E + +GY G+ R A+A + Sbjct: 35 IIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGYFPTVGSPEAREAVATWWRNSFVH 94 Query: 152 --------IGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQF 203 + D+ V S G+ + + + + V P +P Y Sbjct: 95 KEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHY------------- 141 Query: 204 NTDVQKYG-NIEYMRCTPENGFFPDLSTVGR-----TDIIFFCSPNNPTGAAATREQLTQ 257 T + YG + + C PEN + DL + R T ++ +P+NP G+ +R+ + Sbjct: 142 ETVCKAYGIGMHFYNCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVED 201 Query: 258 LVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAMETASF---SKYAGFTGVR 313 +V A++ + D YA M +P + F E + +K G R Sbjct: 202 IVRLAEELRLPLFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWR 261 Query: 314 LGWTVIPKKLLYSD 327 LGW LLY D Sbjct: 262 LGW------LLYVD 269 >3TCM-A nrPDB Length = 500 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 100/401 (24%), Positives = 146/401 (36%), Gaps = 80/401 (19%) Query: 112 AMAKKAHELSTIEGYS--GYGAEQGAKPLRAAIAKTFYG--GLGIGDDDVFVSDGAKCDI 167 ++++ L+ I G + Y QG LR AIA G DD+F++DGA + Sbjct: 111 SISRAKQILAMIPGRATGAYSHSQGIHGLRDAIASGIASRDGFPANADDIFLTDGASPGV 170 Query: 168 SRLQVMFGSNVT--IAVQDPSYPAYVDSSVIMGQT------------GQFNTDVQKYGNI 213 + + N I V P YP Y S + G G +DV+K + Sbjct: 171 HLMMQLLIRNEKDGILVPIPQYPLYSASIALHGGALVPYYLNESTGWGLETSDVKK--QL 228 Query: 214 EYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDS 273 E R N + +P NPTG E +V+F K G +++ D Sbjct: 229 EDARSRGIN-----------VRALVVINPGNPTGQVLAEENQYDIVKFCKNEGLVLLADE 277 Query: 274 AYAMYMSDDNP-----RSIFEIPGAEEVAMETASFSK----YAGFTGVRLGWTVIPKKLL 324 Y + DN + I G E + S+ Y G G R G+ I Sbjct: 278 VYQENIYVDNKKFHSFKKIVRSLGYGEEDLPLVSYQSVSKGYYGECGKRGGYFEI----- 332 Query: 325 YSDGF--PVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIID 382 GF PV + +I N SNI+ LA L +A + YK + I+ Sbjct: 333 --TGFSAPVREQIYKI--ASVNLCSNIT-GQILASLVMNPPKASDESYASYKAEKDGILA 387 Query: 383 T-----------FTSL-GYDVYGGKNAPYVW--VHFPNQS---------SWDVF--AEIL 417 + F L G + A YV+ + P ++ + D F +L Sbjct: 388 SLARRAKALEHAFNKLEGITCNEAEGAMYVFPQICLPQKAIEAAKAANKAPDAFYALRLL 447 Query: 418 EKTHVVTTPGSGFG--PGGEGFVRVSAFGHRENILEACRRF 456 E T +V PGSGFG PG F R + + I RF Sbjct: 448 ESTGIVVVPGSGFGQVPGTWHF-RCTILPQEDKIPAVISRF 487 >1VP4-A nrPDB Length = 425 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 99/412 (24%), Positives = 158/412 (38%), Gaps = 68/412 (16%) Query: 84 HLLKYP-DAQVISLGIGDTTEPIPEVI-TSAMAKKAHELSTIEGYS--GYGAEQGAKPLR 139 +LK+ D IS G G P PE +A+ A E+ E + Y +G L+ Sbjct: 35 EILKFAADKDAISFGGG---VPDPETFPRKELAEIAKEIIEKEYHYTLQYSTTEGDPVLK 91 Query: 140 AAIAKTF---YGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVI 196 I K YG G+ +D++ + G++ + + +F + + V D PAY+ Sbjct: 92 QQILKLLERMYGITGLDEDNLIFTVGSQQALDLIGKLFLDDESYCVLDD--PAYL----- 144 Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGR-------------TDIIFFCSP- 242 G N Q N P DL+ + R I+ S Sbjct: 145 ----GAINAFRQYLAN---FVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNF 197 Query: 243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAMETA 301 +NP G + E+ LVE A+K IV D Y A+ + IF+I G E V + Sbjct: 198 HNPAGVTTSLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGPERVVL-LN 256 Query: 302 SFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQA--GALACLT 359 +FSK G+R+G +K+F R I A S A LA Sbjct: 257 TFSKVLA-PGLRIGMVA------------GSKEFIRKIVQAKQSADLCSPAITHRLAARY 303 Query: 360 PEG---LEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK-----NAPYVWVHFPNQ-SSW 410 E LE + I Y+ ++++ D+ G K ++W+ P +W Sbjct: 304 LERYDLLEQLKPTIELYRRKRTVMLNALEEYFSDIPGVKWVKSEGGLFIWLTLPEGFDTW 363 Query: 411 DVFAEILEKTHVVTTPGSGFGPGGE--GFVRVS-AFGHRENILEACRRFKQL 459 ++F E ++ V PG F E +R+S E I+E +R +++ Sbjct: 364 EMF-EYAKRKKVFYVPGRVFKVYDEPSPSMRLSFCLPPDEKIVEGIKRLREV 414 >3B46-A nrPDB Length = 447 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/177 (25%), Positives = 69/177 (38%), Gaps = 7/177 (3%) Query: 229 STVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSI 287 + +T + +P+NP G TRE+LT L K+ +I+ D Y +Y +D R Sbjct: 197 AITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFTDSFTRIA 256 Query: 288 FEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGAS 347 P ++ + S K TG R+GW + L S AK RI CF S Sbjct: 257 TLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYA---AKAHTRI---CFASPS 310 Query: 348 NISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHF 404 + +A A + + K+ Y I F LG + +V V F Sbjct: 311 PLQEACANSINDALKIGYFEKMRQEYINKFKIFTSIFDELGLPYTAPEGTYFVLVDF 367 >3PDX-A nrPDB Length = 402 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 89/393 (22%), Positives = 144/393 (36%), Gaps = 48/393 (12%) Query: 89 PDAQVISLGIGDTTE----PIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAK 144 P+ VISL IGD T P +T AM K A + Y+GY G R +A Sbjct: 29 PNKTVISLSIGDPTVFGNLPTDPEVTQAM-KDALDSGK---YNGYAPSIGYLSSREEVAS 84 Query: 145 TFYGGLG-IGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQ 202 ++ + DV ++ G I L V+ I + P + Y + MG Sbjct: 85 YYHCPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESMG---- 140 Query: 203 FNTDVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQ 257 +V+ Y + PE + DL + +T + +P+NP G+ ++ L + Sbjct: 141 --IEVKLYNLL------PEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHLQK 192 Query: 258 LVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWT 317 ++ A++ I+ D Y + D + +K G RLGW Sbjct: 193 ILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVPILSCGGLAKRWLVPGWRLGWI 252 Query: 318 VIPKKL-----LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGF 372 +I + DG + K RI+ G I Q + L E + F Sbjct: 253 LIHDRRDIFGNEIRDG--LVKLSQRIL-----GPCTIVQGALKSILQRTPQEFYQDTLSF 305 Query: 373 YKENTNIIIDTFTSL-GYDVYGGKNAPYVWV-----HFPNQSSWDVFAE-ILEKTHVVTT 425 K N ++ +++ G A Y+ V HFP + F E ++ + V Sbjct: 306 LKSNADLCYGALSAIPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQSVHCL 365 Query: 426 PGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 P + F F RV +LEAC R ++ Sbjct: 366 PATCF--EYPNFFRVVITVPEVMMLEACSRIQE 396 >2ZYJ-A nrPDB Length = 397 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 80/350 (22%), Positives = 136/350 (38%), Gaps = 45/350 (12%) Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSY 187 Y +G PLRA +A+ +G+ ++V ++ G++ + + +V + ++ PSY Sbjct: 70 YSPTEGYAPLRAFVAEW----IGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSY 125 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFC-SPNNPT 246 MG F ++ + P+ ++ R ++ S NPT Sbjct: 126 ---------MGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKRERPRFLYLIPSFQNPT 176 Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEI------PGAEEVAME 299 G +L++ + G ++V D AY +Y + S+FE+ PG + Sbjct: 177 GGLTPLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPG----VIY 232 Query: 300 TASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 SFSK G+R+ + V + L AK + N + L Sbjct: 233 LGSFSKVLS-PGLRVAFAVAHPEALQK--LVQAKQGADLHTPMLNQM-------LVHELL 282 Query: 360 PEGL-EAMHKVIGFYKENTNII---IDTFTSLGYDVYGGKNAPYVWVHFPN-QSSWDVFA 414 EG E + +V Y+E + +D K +VW+ P S+ +F Sbjct: 283 KEGFSERLERVRRVYREKAQAMLHALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLFR 342 Query: 415 EILEKTHVVTTPGSGF--GPGGEGFVRVS-AFGHRENILEACRRFKQLYK 461 LE+ +V PG F GGE +R+S A RE I E RR + K Sbjct: 343 RALEE-NVAFVPGGPFFANGGGENTLRLSYATLDREGIAEGVRRLGRALK 391 >4R2N-A nrPDB Length = 367 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Query: 228 LSTV-GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD-NPR 285 L+TV RT +IF C+PNNPT + L + VE A +I D AY Y+ D P Sbjct: 141 LATVTDRTRLIFVCNPNNPTSTVVGPDALARFVE-AVPAHILIAIDEAYVEYIRDGMRPD 199 Query: 286 SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTV 318 S+ + V + +FSK G G+R+G+ + Sbjct: 200 SLGLVRAHNNVVV-LRTFSKAYGLAGLRIGYAI 231 >3FVS-A nrPDB Length = 422 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 55/242 (22%), Positives = 97/242 (40%), Gaps = 15/242 (6%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGI 152 V++LG G P P+ A H +S + Y G PL +A F LG Sbjct: 30 VVNLGQGFPDFPPPDFAVEAFQ---HAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 Query: 153 GDD---DVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 208 D +V V+ G + + Q + + + +P + Y +++ G F + Sbjct: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS--L 144 Query: 209 KYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAK 263 K G I+ + + D + RT + +PNNP G +RE+L + + Sbjct: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ 204 Query: 264 KNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKK 322 ++ + + D Y + D + SI +PG E + S K TG ++GW + P Sbjct: 205 QHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 Query: 323 LL 324 ++ Sbjct: 265 IM 266 >4WP0-A nrPDB Length = 472 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 55/245 (22%), Positives = 98/245 (40%), Gaps = 15/245 (6%) Query: 90 DAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGG 149 + V++LG G P P+ A H +S + Y G PL +A F Sbjct: 27 EHDVVNLGQGFPDFPPPDFAVEAFQ---HAVSGDFMLNQYTKTFGYPPLTKILASFFGEL 83 Query: 150 LGIGDD---DVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNT 205 LG D +V V+ G + + Q + + + +P + Y +++ G F + Sbjct: 84 LGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS 143 Query: 206 DVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVE 260 K G I+ + + D + RT + +PNNP G +RE+L + Sbjct: 144 --LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVAS 201 Query: 261 FAKKNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319 +++ + + D Y + D + SI +PG E + S K TG ++GW + Sbjct: 202 LCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLG 261 Query: 320 PKKLL 324 P ++ Sbjct: 262 PDHIM 266 >3B1C-A nrPDB Length = 392 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 87/416 (20%), Positives = 148/416 (35%), Gaps = 66/416 (15%) Query: 70 AGYLFPEIARRRSAHLLKYP----DAQVISLGIGDTT-EPIPEVITSAMAKKAHELSTIE 124 + Y F R S H K+ D Q++ I D E +PEV A+ A +L + Sbjct: 6 SKYNFQTAPNRLSHHTYKWKETETDPQLLPAWIADMDFEVMPEV-KQAIHDYAEQL--VY 62 Query: 125 GYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQ 183 GY+ E L ++ Y +D+ +G IS +Q + + Sbjct: 63 GYTYASDELLQAVLDWEKSEHQYS---FDKEDIVFVEGVVPAISIAIQAFTKEGEAVLIN 119 Query: 184 DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDII------ 237 P YP + S + + N+ ENG F DI+ Sbjct: 120 SPVYPPFARSVRLNNRKLVSNS------------LKEENGLFQIDFEQLENDIVENDVKL 167 Query: 238 -FFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI--PGAE 294 C+P+NP G RE L Q+ +K+ I+V D + + F P + Sbjct: 168 YLLCNPHNPGGRVWEREVLEQIGHLCQKHHVILVSDEIHQDLTLFGHEHVSFNTVSPDFK 227 Query: 295 EVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCF------NGASN 348 + A+ +S +K G + + +I N +C F N Sbjct: 228 DFALVLSSATKTFNIAGTKNSYAIIE---------------NPTLCAQFKHQQLVNNHHE 272 Query: 349 ISQAGALACLT-----PEGLEAMHKVIGFYKENTNIIIDTFTSLG--YDVYGGKNAPYVW 401 +S G +A T L A+ V+ +EN ++ F V + +W Sbjct: 273 VSSLGYIATETAYRYGKPWLVALKAVL---EENIQFAVEYFAQEAPRLKVMKPQGTYLIW 329 Query: 402 VHFPNQSSWD--VFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 455 + F + D +F + ++ V+ GS +G GE R++ + + E C+R Sbjct: 330 LDFSDYGLTDDALFTLLHDQAKVILNRGSDYGSEGELHARLNIAAPKSLVEEICKR 385 >2ZJG-A nrPDB Length = 410 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR-SIFEIP 291 +T I +P+NP G TR++L + + K+ ++ + D Y + + I +P Sbjct: 167 KTKAIILNTPHNPLGKVYTRQELQVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLP 226 Query: 292 GAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 G E + S K TG +LGW++ P L+ Sbjct: 227 GMWERTITIGSAGKTFSVTGWKLGWSIGPAHLI 259 >6EZL-A nrPDB Length = 404 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 23/170 (13%) Query: 165 CDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIE-YMRCTPENG 223 C ++R+ + + + DP++P + +M TD++KY + RC +G Sbjct: 113 CFLARV---LSRDTPVYISDPTWP---NHYAVMAAANL--TDLRKYRYYDNAKRCIDFDG 164 Query: 224 FFPDLSTV--GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS- 280 DL+ G I+ C+ +NPTG T EQ +++E + I +DSAY Y + Sbjct: 165 LLEDLNGAPEGSIVILHACA-HNPTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATG 223 Query: 281 --DDNPRSI--FEIPGAEEVAMETASFSKYAGFTGVRLGWTVI----PKK 322 D++ SI F G E + + S+SK G R+G I PKK Sbjct: 224 SLDNDAYSIRLFARQGMEMLLAQ--SYSKNMGLYAERVGVCSIVTANPKK 271 >4RAE-A nrPDB Length = 394 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 50/216 (23%), Positives = 89/216 (41%), Gaps = 23/216 (10%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG 292 + D++F SPNNP+G + + L +L++ A I + D AY + S + S+ E Sbjct: 166 KPDVVFIASPNNPSGQSVSLPDLCKLLDVAP---GIAIVDEAYGEFSSQPSAVSLVEEYP 222 Query: 293 AEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQA 352 ++ V T SK F G RLG+ + P D ++ ++ S+++QA Sbjct: 223 SKLVVTRT--MSKAFAFAGGRLGYLI---------ATPAVIDAMLLVRLPYH-LSSVTQA 270 Query: 353 GALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ-SSWD 411 A A L + + V E + + +G+ V ++ F + ++W Sbjct: 271 AARAALR-HSDDTLSSVAALIAERERVTT-SLNDMGFRVIPSDANFVLFGEFADAPAAWR 328 Query: 412 VFAEILEKTHVVTTPG-----SGFGPGGEGFVRVSA 442 + E V PG +G + F+R SA Sbjct: 329 RYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASA 364 >3GET-A nrPDB Length = 365 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 47/205 (22%), Positives = 91/205 (44%), Gaps = 35/205 (17%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIF---EIPG 292 +IF C PNNP G + T+ ++ ++ ++V D+AY + S + + E+ Sbjct: 156 LIFLCLPNNPLGECLDASEATEFIKGVNED-CLVVIDAAYNEFASFKDSKKHLEPCELIK 214 Query: 293 AEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQA 352 + + +FSK G G+R+G+ + ++ S + + FN SN++ Sbjct: 215 EFDNVLYLGTFSKLYGLGGLRIGYGIANANII-SAFYKLRAPFN---------VSNLALK 264 Query: 353 GALACL-----TPEGLEAMHKVIGFYKE---NTNI-IIDTFTSLGYDVYGGKNAPYVWVH 403 A+A + T + LE + YKE NI IID++T+ ++ Sbjct: 265 AAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTN------------FITYF 312 Query: 404 FPNQSSWDVFAEILEKTHVVTTPGS 428 F ++S D+ ++L+K ++ S Sbjct: 313 FDEKNSTDLSEKLLKKGIIIRNLKS 337 >3FKD-A nrPDB Length = 350 Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 37/199 (18%) Query: 132 EQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAY 190 E A LR +AK + ++ + V++G ++ Q GS IA+ PS+ Y Sbjct: 49 EPDAGTLRQMLAKRN----SVDNNAILVTNGPTAAFYQIAQAFRGSRSLIAI--PSFAEY 102 Query: 191 VDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI-----IFFCSPNNP 245 D+ + E+ C F+P +G D + C+PNNP Sbjct: 103 EDACRMY----------------EHEVC-----FYPSNEDIGEADFSNMDFCWLCNPNNP 141 Query: 246 TGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSK 305 G R ++ +L+ + V D +Y + +++ R +I G + + M SFS Sbjct: 142 DGRLLQRTEILRLLN--DHPDTTFVLDQSYVSFTTEEVIRPA-DIKGRKNLVM-VYSFSH 197 Query: 306 YAGFTGVRLGWTVIPKKLL 324 G G+R+G+ V K + Sbjct: 198 AYGIPGLRIGYIVANKDFM 216 >3FDB-A nrPDB Length = 377 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/229 (21%), Positives = 96/229 (41%), Gaps = 18/229 (7%) Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG-AEE 295 I C+P NP G E L +L + A + + ++ D +A + D + A Sbjct: 154 ILLCNPYNPLGMVFAPEWLNELCDLAHRYDARVLVDEIHAPLVFDGQHTVAAGVSDTAAS 213 Query: 296 VAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGAL 355 V + + SK G++ ++++S+ A+ + ++ +GAS + A Sbjct: 214 VCITITAPSKAWNIAGLKCA------QIIFSNP-SDAEHWQQLSPVIKDGASTLGLIAAE 266 Query: 356 ACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAP-----YVWVHFPNQSSW 410 A G + +++ + + K N + ++ + + G K P +W+ F + + Sbjct: 267 AAYR-YGTDFLNQEVAYLKNNHDFLLH---EIPKRIPGAKITPMQATYLMWIDFRDTTIE 322 Query: 411 DVFAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 +E +EK V G+ FG G GF R++ RE + EA R + Sbjct: 323 GSPSEFFIEKAKVAMNDGAWFGEDGTGFCRLNFATSREVLEEAIDRMAK 371 >3DZZ-A nrPDB Length = 391 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 63/291 (21%), Positives = 122/291 (41%), Gaps = 30/291 (10%) Query: 180 IAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRT---DI 236 I VQ+P Y + SVI G + + Y N +Y + + DL T + Sbjct: 112 ILVQEPVYNMFY--SVIEGNGRRVISSDLIYENSKY------SVNWADLEEKLATPSVRM 163 Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIP-GAE 294 + FC+P+NP G A + E++ ++ E K+ +++ D + + ++D++ F + A+ Sbjct: 164 MVFCNPHNPIGYAWSEEEVKRIAELCAKHQVLLISDEIHGDLVLTDEDITPAFTVDWDAK 223 Query: 295 EVAMETASFSKYAGFTGVRLGWTVIPKKLLYS---DGFPVAKDFNRIICTCFNGASNISQ 351 + S SK + +IP L + + F +A G N+ Sbjct: 224 NWVVSLISPSKTFNLAALHAACAIIPNPDLRARAEESFFLAG----------IGEPNLLA 273 Query: 352 AGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDV-YGGKNAPYV-WVHFP--NQ 407 A EG + + ++ ++N + +V NA Y+ WV Sbjct: 274 IPAAIAAYEEGHDWLRELKQVLRDNFAYAREFLAKEVPEVKVLDSNASYLAWVDISALGM 333 Query: 408 SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 ++ D + EKT ++ + G+G+ G FVR++ +E +++ +R KQ Sbjct: 334 NAEDFCKYLREKTGLIISAGNGYRGNGHEFVRINLACPKELVIDGMQRLKQ 384 >1YIY-A nrPDB Length = 429 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 1/93 (1%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIP 291 +T +I +P+NP G R +L + KK + V D Y M I +P Sbjct: 182 KTKMIIINTPHNPLGKVMDRAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEHIRICTLP 241 Query: 292 GAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 G E + S K TG ++GW P+ LL Sbjct: 242 GMWERTITIGSAGKTFSLTGWKIGWAYGPEALL 274 >3LY1-A nrPDB Length = 354 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 4/85 (4%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI--PGA 293 I++ +PNNPTG + + + +K ++ + D AYA +++D RSI + GA Sbjct: 144 IVYLVNPNNPTGTITPADVIEPWIA-SKPANTMFIVDEAYAEFVNDPRFRSISPMITQGA 202 Query: 294 EEVAMETASFSKYAGFTGVRLGWTV 318 E + + +FSK G+R+G+ V Sbjct: 203 ENIIL-LKTFSKIHAMAGMRVGYAV 226 >1UU1-A nrPDB Length = 335 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 27/153 (17%) Query: 230 TVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFE 289 VG D++F +PNNPTG RE++ +++ K G+ + D AY + + S + Sbjct: 135 NVGEGDVVFIPNPNNPTGHVFEREEIERIL----KTGAFVALDEAYYEFHGE----SYVD 186 Query: 290 IPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNI 349 E +FSK R+G+ V +K + + +NR+ FN S + Sbjct: 187 FLKKYENLAVIRTFSKAFSLAAQRVGYVVASEKFIDA--------YNRVRLP-FN-VSYV 236 Query: 350 SQAGALACLTPEGLEAMHKVIGFYKENTNIIID 382 SQ A L H+ I ++E T I++ Sbjct: 237 SQMFAKVALD-------HREI--FEERTKFIVE 260 >4DQ6-A nrPDB Length = 391 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 65/296 (21%), Positives = 119/296 (40%), Gaps = 33/296 (11%) Query: 176 SNVTIAVQDPSYPAYVDSSVIMGQTGQFN-TDVQKYGNIEYMRCTPENGFFPDL-STVGR 233 +N I +Q+P Y + +SV+ + + +QK N Y+ + D+ + + Sbjct: 113 ANDKIMIQEPVYSPF--NSVVKNNNRELIISPLQKLENGNYIMD------YEDIENKIKD 164 Query: 234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 + C+P+NP G T+++L +L + K+ I+ D + SD + IP A Sbjct: 165 VKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIH----SDIILKKHKHIPMA 220 Query: 294 ------EEVAMETASFSKYAGFTGVRLGWTVIPKK---LLYSDGFPVAKDFNRIICTCFN 344 E+ + + +K G++ + V+P + L D F D R CF+ Sbjct: 221 SISKEFEKNTITCMAPTKTFNIAGLQSSYVVLPDEKDYKLLDDAF-TRIDIKR--NNCFS 277 Query: 345 GASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHF 404 + + LE + I F + N + L V + +WV F Sbjct: 278 LVATEASYNNGESWLESFLEYLESNIDFAIKYIN---ENMPKLK--VRKPEGTYLLWVDF 332 Query: 405 P--NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 S ++ + +++K V G+ FG GG G+ R++ R + EA R K Sbjct: 333 SALGLSDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKN 388 >3CQ5-A nrPDB Length = 369 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 60/265 (22%), Positives = 107/265 (40%), Gaps = 31/265 (11%) Query: 63 SNMSKLQAGYLFPEIARRRSAHLLKYPDAQV-ISLGIGDTTEPIPEVITSAMAKKAHELS 121 S+M+K+ L P R H P V I L + P E + + + +++ Sbjct: 2 SHMTKITLSDL-PLREELRGEHAYGAPQLNVDIRLNTNENPYPPSEALVADLVATVDKIA 60 Query: 122 T-IEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTI 180 T + Y A + L A I K G+ + D+++ ++G+ + +L FG Sbjct: 61 TELNRYPERDAVELRDELAAYITKQ--TGVAVTRDNLWAANGSNEILQQLLQAFGGPGRT 118 Query: 181 AVQ-DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV------GR 233 A+ PSY + + K + E++ + F D+ + Sbjct: 119 ALGFQPSY--------------SMHPILAKGTHTEFIAVSRGADFRIDMDVALEEIRAKQ 164 Query: 234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 DI+F +PNNPTG + + + +++ A I++ D AYA + + ++ E Sbjct: 165 PDIVFVTTPNNPTGDVTSLDDVERIINVAP---GIVIVDEAYAEFSPSPSATTLLEKYPT 221 Query: 294 EEVAMETASFSKYAGFTGVRLGWTV 318 + V T SK F G RLG+ V Sbjct: 222 KLVVSRT--MSKAFDFAGGRLGYFV 244 >3FTB-A nrPDB Length = 361 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 43/223 (19%), Positives = 91/223 (40%), Gaps = 16/223 (7%) Query: 228 LSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSI 287 +S + D + +PNNP G +E+ +++ A++ I+ D A+ + D + + Sbjct: 139 ISKIDDVDSVIIGNPNNPNGGLINKEKFIHVLKLAEEKKKTIIIDEAFIEFTGDPSSSFV 198 Query: 288 FEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGAS 347 EI + + A +K+ G+R G+ + K + + +N CF Sbjct: 199 GEIKNYSCLFIIRA-MTKFFAMPGIRFGYGITNNKEIAAKIKAKQNPWN---INCF---- 250 Query: 348 NISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGY--DVYGGKNAPYVWVHFP 405 ++ A+ CL + + + + K+ I+ +G+ V+ +A +V Sbjct: 251 --AEMAAINCLKDTNY--IEESLLWIKKERKRFIEELNKIGFIKRVF-SPHANFVLCRLE 305 Query: 406 NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN 448 N S ++ +L K +V F + FVR + ++N Sbjct: 306 NISGEKLYDSLL-KEDIVIRRCCNFIGLDDSFVRFAIKDEKKN 347 >3P1T-A nrPDB Length = 337 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 13/98 (13%) Query: 229 STVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIF 288 + V R D + +P+NPTG A + +L QL + A K ++ D Y Y S F Sbjct: 131 AQVSRDDCVVLANPSNPTGQALSAGELDQLRQRAGK----LLIDETYVDYSS-------F 179 Query: 289 EIPGAE--EVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 G E + SFSK G G+RLG P +L+ Sbjct: 180 RARGLAYGENELVFRSFSKSYGLAGLRLGALFGPSELI 217 >5DJ3-A nrPDB Length = 376 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 2/109 (1%) Query: 169 RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDL 228 R+ + S+V++ + S A VD ++ T D+ + ++ + + DL Sbjct: 83 RVLSCYSSSVSMEILARSLSASVDRVALVHPTFDNIADLLRGNGLDLVPVEEDALHGADL 142 Query: 229 ST--VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 S + +F +PNNPTG E+L +L E ++G+++ D+++ Sbjct: 143 SAELLSSVGCVFVTTPNNPTGRVLAEERLRRLAEQCAEHGTVLALDTSF 191 >5TON-A nrPDB Length = 414 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 76/356 (21%), Positives = 127/356 (35%), Gaps = 36/356 (10%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYG 130 P + + A + PD + ++LG+G D +P + + ++ S++ Y Sbjct: 16 PVLVFKLIADFREDPDPRKVNLGVGAYRTDDCQPWVLPVVRKVEQRIANNSSLN--HEYL 73 Query: 131 AEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS--------RLQVMFGSNVTIAV 182 G R ++ L +GDD + + + R+ F + Sbjct: 74 PILGLAEFRTCASR-----LALGDDSPALQEKRVGGVQSLGGTGALRIGAEFLARWYNGT 128 Query: 183 QDPSYPAYVDSSVIMGQTGQFNT----DVQ--KYGNIEYMRCTPENGFFPDLSTVGRTDI 236 + P YV S G F T D++ +Y + E R GF DL I Sbjct: 129 NNKDTPVYVSSPTWENLNGVFTTAGFKDIRSYRYWDTE-KRGLDLQGFLSDLENAPEFSI 187 Query: 237 -IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE 295 + +NPTG T EQ Q+ K+ +DSAY + S + + + I Sbjct: 188 FVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGNLEKDAWAIRYFVS 247 Query: 296 VAME---TASFSKYAGFTGVRLG-WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQ 351 E SFSK G R+G TV+ K+ V +I+ ++ +Q Sbjct: 248 EGFELFCAQSFSKNFGLYNERVGNLTVVAKE--PDSILRVLSQMQKIVRVTWSNPP--AQ 303 Query: 352 AGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ 407 + T E H+ G K + I+ + L + K P W H +Q Sbjct: 304 GARIVARTLSDPELFHEWTGNVKTMADRILSMRSELRARLEALK-TPGTWNHITDQ 358 >4IX8-A nrPDB Length = 444 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 78/400 (19%), Positives = 157/400 (39%), Gaps = 60/400 (15%) Query: 94 ISLGIGDTTE----PIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIA------ 143 + L IGD T P+++T AM ++ ++GY GA LR ++ Sbjct: 70 LRLSIGDPTVDGNLKTPDIVTEAMV----DVVRSGKFNGYPPTVGADNLRQVVSTYWRRF 125 Query: 144 -KTFYGGLGIGDDDVFVSDG-AKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTG 201 +T + ++V ++ G ++ + L + I V PS+P Y Sbjct: 126 CQTKSRQEALKWENVIITSGVSQAIVLALTALCNEGDNILVCAPSFPHY----------- 174 Query: 202 QFNTDVQKYG-NIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQL 255 + YG Y P + DL T +P+NP G+ +R + Sbjct: 175 --KSVCDSYGIECRYYYLDPSKSWECDLRAAAGMVDSHTKAFVIINPSNPCGSNFSRAHV 232 Query: 256 TQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSI--FEIPGAEEVAMETASFSKYAGFTGV 312 + +++F +++ ++ D YA M +++ S+ F+ + TA KY G Sbjct: 233 SDIIDFCQQHQIPLISDEIYAEMVLNNGIFTSVADFDTNVPRLILGGTA---KYQVCPGW 289 Query: 313 RLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGF 372 R+GW+++ + + + V + + G ++I Q L E ++ Sbjct: 290 RVGWSILIDPMNVAGDWAVGMER---LTQLIAGVNSICQEAIARTLLKCPTECTEHIVTQ 346 Query: 373 YKENTNIIIDTFT-SLGYDVYGGKNAPYVWV-----HFPN-QSSWDVFAEILEKTHVVTT 425 + + +G + + + +V + +F + +S + + ++L++ +V Sbjct: 347 LEAGAKVYARLLEHDIGISMEAPQASMFVMLKLNLSYFQDLKSDMEFYEKLLDEENVQVL 406 Query: 426 PGSGFGPGGEGFVRV-----SAFGHR--ENILEACRRFKQ 458 PG FG GF+R SA + + I+E C R K+ Sbjct: 407 PGEIFGMS--GFLRATVSRPSAVLNEAVDRIIEFCERHKK 444 >1YAA-A nrPDB Length = 412 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%) Query: 222 NGFFPDLSTVGRTDIIFFCS-PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS 280 NGF + I S +NPTG T EQ Q+V+ I ++D+AY + + Sbjct: 164 NGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFAT 223 Query: 281 DDNPRSIFEIP-GAEEVAMET-----ASFSKYAGFTGVRLG 315 D + + + G E+++ + SF+K AG G R+G Sbjct: 224 GDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVG 264 >1AY8-A nrPDB Length = 394 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 8/116 (6%) Query: 162 GAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPE 221 GA L M ++ + V DP++P +V MG +Y + E R Sbjct: 102 GALRQALELARMANPDLRVFVSDPTWPNHVSIMNFMG----LPVQTYRYFDAE-TRGVDF 156 Query: 222 NGFFPDLSTVGRTDIIFF--CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 G DL+ + D++ C +NPTGA T +Q ++ +K G++ + D AY Sbjct: 157 EGMKADLAAAKKGDMVLLHGCC-HNPTGANLTLDQWAEIASILEKTGALPLIDLAY 211 >1LC8-A nrPDB Length = 364 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 12/95 (12%) Query: 226 PDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR 285 PDL D +F C+PNNPTG R L + + K ++ D A+ ++ P Sbjct: 145 PDL------DCLFLCTPNNPTGLLPERPLLQAIADRCKSLNINLILDEAFIDFI----PH 194 Query: 286 SIFEIPGAEE--VAMETASFSKYAGFTGVRLGWTV 318 IP ++ S +K+ G+RLG+ V Sbjct: 195 ETGFIPALKDNPHIWVLRSLTKFYAIPGLRLGYLV 229 >6C3C-A nrPDB Length = 413 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 3/60 (5%) Query: 222 NGFFPDLSTVGRTDIIFFCSPNNPTGAAAT---REQLTQLVEFAKKNGSIIVYDSAYAMY 278 + +P+L RTD +F PNNPTG + R+ ++V F K + +++ D +A + Sbjct: 165 DRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASF 224 >2GB3-A nrPDB Length = 409 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 2/101 (1%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG 292 RT I +P NPTG ++++ LVE A+++G ++ D Y+ + S I Sbjct: 174 RTKGIVLSNPCNPTGVVYGKDEMRYLVEIAERHGLFLIVDEVYSEIVFRGEFASALSIES 233 Query: 293 AEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAK 333 + V ++ S SK G R+G + + L S +A+ Sbjct: 234 DKVVVID--SVSKKFSACGARVGCLITRNEELISHAMKLAQ 272 >1TAR-A nrPDB Length = 401 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 5/102 (4%) Query: 223 GFFPDLSTVGRTDIIFFCS-PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSD 281 G D+S + II + +NPTG +EQ +L KK + +D AY + S Sbjct: 164 GAMEDISKIPEKSIILLHACAHNPTGVDPRQEQWKELASVVKKRNLLAYFDMAYQGFASG 223 Query: 282 DNPRSIFEIPGAEEVAME---TASFSKYAGFTGVRLG-WTVI 319 D R + + E ++ + S++K G G R G +TVI Sbjct: 224 DINRDAWALRHFIEQGIDVVLSQSYAKNMGLYGERAGAFTVI 265 >3FFH-A nrPDB Length = 363 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 6/94 (6%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGS--IIVYDSAYAMYMSDDNPRSIFEI 290 +T I++ C+PNNPTG +L + F + S ++V D AY Y++ P ++ Sbjct: 155 KTTIVWICNPNNPTGNYI---ELADIQAFLDRVPSDVLVVLDEAYIEYVT-PQPEKHEKL 210 Query: 291 PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 + + T +FSK G R+G+ + K+++ Sbjct: 211 VRTYKNLIITRTFSKIYGLASARVGYGIADKEII 244 >2O0R-A nrPDB Length = 411 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 61/246 (24%), Positives = 95/246 (38%), Gaps = 32/246 (13%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN---PRSIFE 289 RT + SP+NPTGA + +L + E A +++ D Y + D P + F+ Sbjct: 160 RTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFD 219 Query: 290 IPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNI 349 G E + +S +K TG ++GW P +L+ G AK + + G + Sbjct: 220 --GMAERTITISSAAKMFNCTGWKIGWACGPAELIA--GVRAAKQY-----LSYVGGAPF 270 Query: 350 SQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSS 409 A ALA T + A + + + + T +G+ V+ Y P Sbjct: 271 QPAVALALDTEDAWVAALR--NSLRARRDRLAAGLTEIGFAVHDSYGT-YFLCADPRPLG 327 Query: 410 WD----VFAEILEKTHVVTTPGSGFGPGGEG-----------FVRVSAFGHRENIL-EAC 453 +D A + EK V P S F G VR + F R++ L EA Sbjct: 328 YDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFT-FCKRDDTLDEAI 386 Query: 454 RRFKQL 459 RR L Sbjct: 387 RRLSVL 392 >3IHJ-A nrPDB Length = 498 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 81/373 (21%), Positives = 142/373 (38%), Gaps = 53/373 (14%) Query: 129 YGAEQGAKPLRAAIAKTFY---GGLGIGDDDVFVSDGAKCDISR-LQVMFG----SNVTI 180 Y A QG +R +A GG+ D+++++ GA IS L+++ S + Sbjct: 125 YSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGV 184 Query: 181 AVQDPSYPAY--VDSSVIMGQTGQFNTDVQKYG-NI-EYMRCTPENGFFPDLSTVGRTDI 236 + P YP Y V S + Q + + + N+ E R E D + Sbjct: 185 MIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCD------PKV 238 Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA--MYMSDDNPRS----IFEI 290 + +P NPTG +R+ + ++ FA + ++ D Y +Y D S ++E+ Sbjct: 239 LCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEM 298 Query: 291 PGAEEVAMETASFSK----YAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGA 346 +E ASF Y G G R G+ + G + K + +C +G Sbjct: 299 GPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKG-QLVKLLSVRLCPPVSGQ 357 Query: 347 SNISQAGALACLTPEGLEAMHK----VIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVW 401 + + E E + V+G + + D F + G + A Y + Sbjct: 358 AAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAF 417 Query: 402 --VHFP---------NQSSWDVF--AEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN 448 + P +Q + D+F ++LE+T + PGSGFG R + R Sbjct: 418 PRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQ------REGTYHFRMT 471 Query: 449 ILEACRRFKQLYK 461 IL + K + + Sbjct: 472 ILPPVEKLKTVLQ 484 >1D2F-A nrPDB Length = 390 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 45/236 (19%), Positives = 87/236 (36%), Gaps = 27/236 (11%) Query: 222 NGFFPDLSTVG------RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 +G+F D+ + I+ CSP NPTG T ++L + + +++G ++ D + Sbjct: 145 DGWFCDMGKLEAVLAKPECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIH 204 Query: 276 AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 335 + + P + + A+ T+ + IP L + G Sbjct: 205 MDMVWGEQPHIPWSNVARGDWALLTSGSKSFN-----------IP-ALTGAYGIIENSSS 252 Query: 336 NRIICTCFNGASNISQAGALACLT-----PEGLEAMHKVIGFYKENTNIIID----TFTS 386 + G +S LA +G + + + K+N I D F Sbjct: 253 RDAYLSALKGRDGLSSPSVLALTAHIAAYQQGAPWLDALRIYLKDNLTYIADKMNAAFPE 312 Query: 387 LGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSA 442 L + + ++ + N + ++E+ V PG +G G GFVR++A Sbjct: 313 LNWQIPQSTYLAWLDLRPLNIDDNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNA 368 >3G7Q-A nrPDB Length = 417 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 14/98 (14%) Query: 185 PSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGF-----FPDLSTVGRTDIIFF 239 P Y Y DS + + + V NIE + PE F F L T +I Sbjct: 136 PEYIGYADSGL------EDDLFVSARPNIELL---PEGQFKYHVDFEHLHIGEETGMICV 186 Query: 240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAM 277 P NPTG T E+L +L A ++ +V D+AY + Sbjct: 187 SRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGV 224 >2X8U-A nrPDB Length = 412 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 255 LTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE-EVAMETASFSKYAGFTG 311 L ++V +KK+G++I+ D A+ M ++ R +FE G E +V +FSK G G Sbjct: 193 LQEMVAVSKKHGAMILVDEAHGMGFFGEHGRGVFEEAGVEADVDFVVGTFSKSVGTVG 250 >4GDY-A nrPDB Length = 439 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 19/183 (10%) Query: 153 GDDDVFVSDGAK---CDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 G D+ V+ G++ C + + + G NV + +P+Y + S +G N + Sbjct: 107 GQMDLCVTSGSQQGLCKVFEMIINPGDNVLL--DEPAYSGTLQSLHPLG-CNIINVASDE 163 Query: 210 YGNIE------YMRCTPENGFFPDLSTVGRTDIIFFCSPN--NPTGAAATREQLTQLVEF 261 G + R PE+ P +T + PN NPTG + T E+ ++ E Sbjct: 164 SGIVPDSLRDILSRWKPEDAKNPQKNTPK----FLYTVPNGNNPTGNSLTSERKKEIYEL 219 Query: 262 AKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321 A+K +I+ D Y + F + + SFSK +G+R+G+ PK Sbjct: 220 ARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIIS-SGLRIGFLTGPK 278 Query: 322 KLL 324 L+ Sbjct: 279 PLI 281 >3IF2-A nrPDB Length = 444 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 25/181 (13%) Query: 121 STIEGYSGYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGAKCDISRLQVMFGSNV 178 S I + Y QG A+ F + + +++ +++G++ L +FG Sbjct: 71 SAIISMANYSNPQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFGGAF 130 Query: 179 TIAVQDPSYPAYVDSSVIMGQTGQF--NTDVQKYG--------NIEYMRCTPENGFF--- 225 VD S+++ T ++ +DV G +I+ + E GFF Sbjct: 131 VNEHSQDKESKSVDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTHDGEEGFFKYR 190 Query: 226 ---------PDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA 276 P L GR I P NPTG T E++ L E AK+ ++ D+AY Sbjct: 191 VDFEALENLPALKE-GRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYG 249 Query: 277 M 277 M Sbjct: 250 M 250 >4WBT-A nrPDB Length = 376 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Query: 228 LSTVGRTD--IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR 285 L+ VGR + +++ +P+NP G+ E++ + A +++V D AY D Sbjct: 152 LAAVGRENAPLVYLANPDNPMGSWWPAERVVAFAQ-ALPETTLLVLDEAYCETAPRDALP 210 Query: 286 SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTV 318 I + V + +FSK G G R+G+T+ Sbjct: 211 PIESLIDKPNV-IRARTFSKAYGLAGARIGYTL 242 >3L8A-A nrPDB Length = 421 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 22/40 (55%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 I CSP+NP G + L ++ E KK+G I+V D + Sbjct: 197 IYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILVSDEIH 236 >1M4N-A nrPDB Length = 435 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 61/300 (20%), Positives = 105/300 (35%), Gaps = 66/300 (22%) Query: 203 FNTDVQKYGNIEY--MRCTPENGFFPDLSTVG-----------RTDIIFFCSPNNPTGAA 249 F+ D++ +E + CT NGF + + R + +P+NP G Sbjct: 148 FDRDLKWRTGVEIVPIHCTSSNGFQITETALEEAYQEAEKRNLRVKGVLVTNPSNPLGTT 207 Query: 250 ATREQLTQLVEFAKKNGSIIVYDSAYA----------MYMSDDNPRSIFEIPGAEEVAME 299 TR +L L+ F + G ++ D Y+ M R+ E + Sbjct: 208 MTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCDENSEVWQRVHV 267 Query: 300 TASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 S SK G G R+G + +D VA A+ +S G ++ T Sbjct: 268 VYSLSKDLGLPGFRVG------AIYSNDDMVVA------------AATKMSSFGLVSSQT 309 Query: 360 PEGLEAM--------------HKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP 405 L AM HK + K+ ++ G G + WV Sbjct: 310 QHLLSAMLSDKKLTKNYIAENHKRL---KQRQKKLVSGLQKSGISCLNGNAGLFCWVDMR 366 Query: 406 N-------QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILE-ACRRFK 457 + ++ +++ +I+ + H+ +PGS G+ RV E L+ A +R K Sbjct: 367 HLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWFRVCFANLPERTLDLAMQRLK 426 >3G0T-A nrPDB Length = 437 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 8/109 (7%) Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY-AMYMSDD-----NPRSIFEI 290 I + +PNNPT T E+L + E A K+ I++ D AY M D P + Sbjct: 186 IIYSNPNNPTWQCMTDEELRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSV 245 Query: 291 PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFP-VAKDFNRI 338 + + S SK + G R+G +I K LY +P + + F R+ Sbjct: 246 ANYTDNYILALSSSKAFSYAGQRIGVLMISGK-LYEREYPDLEESFGRL 293 >3II0-A nrPDB Length = 422 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 60/264 (22%), Positives = 97/264 (36%), Gaps = 32/264 (12%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIG----DTTEP-IPEVITSAMAKKAHELSTIEGYSGY 129 P + + +A + PD + ++LG+G D P + V+ K A++ S Y Sbjct: 3 PVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPI 62 Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS--------RLQVMFGSNVTIA 181 G R+ ++ L +GDD + + + R+ F + Sbjct: 63 ---LGLAEFRSCASR-----LALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNG 114 Query: 182 VQDPSYPAYVDSSVIMGQTGQFNT----DVQ--KYGNIEYMRCTPENGFFPDLSTVGRTD 235 + + P YV S F+ D++ +Y + E R GF DL Sbjct: 115 TNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAE-KRGLDLQGFLNDLENAPEFS 173 Query: 236 IIFFCS-PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE 294 I+ + +NPTG T EQ Q+ K +DSAY + S + R + I Sbjct: 174 IVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFV 233 Query: 295 EVAME---TASFSKYAGFTGVRLG 315 E SFSK G R+G Sbjct: 234 SEGFEFFCAQSFSKNFGLYNERVG 257 >5Z0Q-C nrPDB Length = 389 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 42/203 (20%), Positives = 78/203 (38%), Gaps = 14/203 (6%) Query: 76 EIARRRSAHLL--KYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQ 133 I RR S L KY D ++ L I DT + I A+ ++ + G GYG Sbjct: 16 RIDRRHSDSLKWKKYADRDILPLWIADTDFRAADCIIDALQQRVQQ-----GVFGYGVTS 70 Query: 134 GAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVD 192 A A G I + + G I+ ++ ++ + P YP + Sbjct: 71 EALAEVAIERMESRFGWKIQPEWLVFLPGVVTGINIAVRAFTEAHQSTVSATPIYPPFFL 130 Query: 193 SSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATR 252 + + G+ + +E R + D + G ++ C+P+NP G R Sbjct: 131 APKLAGRQ-----HLSAALRLEQQRWVLDLDSHEDRMS-GNEKLLLLCNPHNPGGTVYRR 184 Query: 253 EQLTQLVEFAKKNGSIIVYDSAY 275 ++L + FA+++ ++ D + Sbjct: 185 KELEAQLRFAQRHDLLVCSDEIH 207 >1C7O-A nrPDB Length = 399 Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust. Identities = 49/251 (19%), Positives = 95/251 (37%), Gaps = 35/251 (13%) Query: 228 LSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSI 287 LS + FCSP+NP G +++L ++ + K+ ++ D + + ++ Sbjct: 159 LSKDKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLIMPGYEHTV 218 Query: 288 FEIPGAEEVAMETASF---SKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFN 344 F+ E++A +T +F SK G+ + +I N I F Sbjct: 219 FQ-SIDEQLADKTITFTAPSKTFNIAGMGMSNIIIK---------------NPDIRERFT 262 Query: 345 GASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKN----APYV 400 + + + L + E +K G + + +ID + D + + AP + Sbjct: 263 KSRDATSGMPFTTLGYKACEICYKECGKWLDGCIKVIDKNQRIVKDFFEVNHPEIKAPLI 322 Query: 401 ------WVHFP----NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENIL 450 W+ F + + + F ++ K + G FG GG GF R++ I Sbjct: 323 EGTYLQWIDFRALKMDHKAMEEF--MIHKAQIFFDEGYIFGDGGIGFERINLAAPSSVIQ 380 Query: 451 EACRRFKQLYK 461 E+ R + K Sbjct: 381 ESLERLNKALK 391 >3MEB-A nrPDB Length = 448 Score = 35.8 bits (81), Expect = 0.045, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 3/86 (3%) Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG 292 ++ +F +NP+G T Q +L+ K+ I +DSAY + + F + Sbjct: 202 KSIFLFHACAHNPSGIDFTEAQWKELLPIMKEKKHIAFFDSAYQGFATGSFEADAFAVRM 261 Query: 293 AEEVAMET---ASFSKYAGFTGVRLG 315 + +E SFSK G G R+G Sbjct: 262 FVDAGVEVLVAQSFSKNFGLYGERIG 287 >3PD6-B nrPDB Length = 401 Score = 35.4 bits (80), Expect = 0.048, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 5/105 (4%) Query: 222 NGFFPDLSTVGRTDIIFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS 280 +G D+S + ++ +NPTG EQ ++ KK +D AY + S Sbjct: 163 SGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFAS 222 Query: 281 DDNPRSIFEIPGAEEVAMETA---SFSKYAGFTGVRLG-WTVIPK 321 D + + + E + S++K G G R+G +TV+ K Sbjct: 223 GDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCK 267 >1IJI-A nrPDB Length = 356 Score = 35.4 bits (80), Expect = 0.050, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE 295 +++ CSPNNPTG + L+E + +I+V D AY + P++ AE Sbjct: 149 VVYVCSPNNPTGQLINPQDFRTLLELT-RGKAIVVADEAYIEFC----PQASLAGWLAEY 203 Query: 296 VAMETA-SFSKYAGFTGVRLGWTVIPKKLL 324 + + SK G+R G+T+ ++++ Sbjct: 204 PHLAILRTLSKAFALAGLRCGFTLANEEVI 233 >2ZY3-A nrPDB Length = 546 Score = 35.4 bits (80), Expect = 0.055, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 7/82 (8%) Query: 237 IFFC-SPNNPTGAAATREQLTQLVEFAKKN--GSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 IFFC +P+NP + L ++ ++ +I+ D Y + D+ +S+F I Sbjct: 248 IFFCVNPSNPPSVKMDQRSLERVRNIVAEHRPDLMILTDDVYGTFA--DDFQSLFAI--C 303 Query: 294 EEVAMETASFSKYAGFTGVRLG 315 E + SFSKY G TG RLG Sbjct: 304 PENTLLVYSFSKYFGATGWRLG 325 >4BMK-A nrPDB Length = 442 Score = 35.4 bits (80), Expect = 0.056, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 255 LTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE-EVAMETASFSKYAGFTG 311 L ++V AKK+G++++ D A++M N R ++E G E ++ +FS G G Sbjct: 235 LKEMVAVAKKHGAMVLVDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSASVGTVG 292 >3NRA-A nrPDB Length = 407 Score = 35.0 bits (79), Expect = 0.065, Method: Compositional matrix adjust. Identities = 12/41 (29%), Positives = 23/41 (56%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA 276 + F +PNNP G + E++ Q+ A + G+ ++ D Y+ Sbjct: 182 VFLFSNPNNPAGVVYSAEEIGQIAALAARYGATVIADQLYS 222 >2ZY2-A nrPDB Length = 544 Score = 34.7 bits (78), Expect = 0.083, Method: Compositional matrix adjust. Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 11/107 (10%) Query: 216 MRCTPENGFF---PDLSTVGRTDI-IFFC-SPNNPTGAAATREQLTQL--VEFAKKNGSI 268 + P+NG+ +L + D+ IFFC +P+NP + L ++ + ++ + Sbjct: 222 IHADPDNGWQYSDAELDKLKDPDVKIFFCVNPSNPPSVKMDQRSLDRVRAIVAEQRPDLL 281 Query: 269 IVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 I+ D Y + D +S+F + + SFSKY G TG RLG Sbjct: 282 ILTDDVYGTFA--DEFQSLFSV--CPRNTLLVYSFSKYFGATGWRLG 324 >6HNB-A nrPDB Length = 491 Score = 34.7 bits (78), Expect = 0.088, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 31/161 (19%) Query: 240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY-----AMYMSDDNPRSIFEIPGAE 294 C+ NPTG++ + E+ Q+ + A K +I+ D Y Y D R + + Sbjct: 214 CTGQNPTGSSLSAERRKQIYDIACKYDFLIIEDEPYYFLQMETYTKDKAAREGKAVHDHD 273 Query: 295 EV----------------AMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRI 338 E + SFSK G+RLGW V K LL + + R+ Sbjct: 274 EFLKALVPSFISLDVEGRVVRLDSFSKVLA-PGLRLGWIVGQKDLL--------ERYVRL 324 Query: 339 ICTCFNGASNISQAGALACLTPEGLEA-MHKVIGFYKENTN 378 S S+A A A L G + +IG E T+ Sbjct: 325 HEVSVQNPSGFSEALANALLRKWGHSGYLDWLIGLRAEYTH 365 >3K7Y-A nrPDB Length = 405 Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust. Identities = 48/225 (21%), Positives = 86/225 (38%), Gaps = 34/225 (15%) Query: 145 TFYGGLGIGDDDVFVSDGAKCDIS----------RLQVMFGSNV-TIAVQDPSYPAYVDS 193 T L G++ ++ D C I L+ + NV T+ V +P Y +V+ Sbjct: 79 TLTQNLIFGNNSKYIEDKKICTIQCIGGTGAIFVLLEFLKMLNVETLYVTNPPYINHVN- 137 Query: 194 SVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-GRTDIIFFCSPNNPTGAAATR 252 M ++ FN + + + + F DL + + +I S NP Sbjct: 138 ---MIESRGFNLKYINFFDYNLIDINYD-LFLNDLRNIPNGSSVILQISCYNPCSVNIEE 193 Query: 253 EQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE--VAMETA-SFSKYAGF 309 + +++E +I++D AY + + + I EE +A SFSK Sbjct: 194 KYFDEIIEIVLHKKHVIIFDIAYQGFGHTNLEEDVLLIRKFEEKNIAFSVCQSFSKNMSL 253 Query: 310 TGVRLGWTVI------PKKLLYSDGFPVAKDF--------NRIIC 340 G R G I KK+++++ + + F NRI+C Sbjct: 254 YGERAGALHIVCKNQEEKKIVFNNLCFIVRKFYSSPVIHTNRILC 298 >3FDD-A nrPDB Length = 533 Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust. Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 7/92 (7%) Query: 237 IFFC-SPNNPTGAAATREQLTQLVEFAKKN--GSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 IFFC +P+NP L ++ + ++ +I+ D Y + D +S+F I A Sbjct: 248 IFFCVNPSNPPSVKMDERSLERVRKIVAEHRPDLMILTDDVYGTFA--DGFQSLFAICPA 305 Query: 294 EEVAMETASFSKYAGFTGVRLGWTVIPKKLLY 325 + + SFSKY G TG RLG K+ ++ Sbjct: 306 NTLLV--YSFSKYFGATGWRLGVVAAHKENIF 335 >3FSL-A nrPDB Length = 397 Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 222 NGFFPDLSTVGRTDIIFF--CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYM 279 N L T+ I+ C +NPTGA T +Q ++E K I D AY + Sbjct: 161 NDLLATLKTLQAGSIVLLHPCC-HNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFG 219 Query: 280 S--DDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 + +++ +I I A A+ + SFSK G R+G Sbjct: 220 AGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVG 257 >2X5F-A nrPDB Length = 430 Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVE----FAKKNGSII--VYDSAYAMYMSDDNPRSIF 288 I+ PNNPTG T +++T +VE A K +I V D+ Y ++ D +S+F Sbjct: 192 IMILNYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFYEDVYTQSLF 250 >1IAY-A nrPDB Length = 428 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 58/232 (25%), Positives = 95/232 (40%), Gaps = 48/232 (20%) Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR--SIFEIPGAE 294 + +P+NP G ++ L ++ F ++ +V D YA + D P+ SI EI + Sbjct: 192 LILTNPSNPLGTTLDKDTLKSVLSFTNQHNIHLVCDEIYAATVF-DTPQFVSIAEILDEQ 250 Query: 295 EVAMETA-------SFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGAS 347 E+ S SK G G R+G ++YS FN + C A Sbjct: 251 EMTYCNKDLVHIVYSLSKDMGLPGFRVG-------IIYS--------FNDDVVNC---AR 292 Query: 348 NISQAGALACLTPEGLEAMHK----VIGFYKENTNII---IDTFTSLGYDVYGGK----N 396 +S G ++ T L AM V F +E+ + FT+ G +V G K N Sbjct: 293 KMSSFGLVSTQTQYFLAAMLSDEKFVDNFLRESAMRLGKRHKHFTN-GLEVVGIKCLKNN 351 Query: 397 A-PYVWVHFP---NQSSWD----VFAEILEKTHVVTTPGSGFGPGGEGFVRV 440 A + W+ +S++D ++ I+ + +PGS F G+ RV Sbjct: 352 AGLFCWMDLRPLLRESTFDSEMSLWRVIINDVKLNVSPGSSFECQEPGWFRV 403 >3F6T-A nrPDB Length = 533 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%) Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSI-IVYDSAYAMYMSDDNPRSIFEIPGAEE 295 + +P NPT L + + +KN + I+ D Y ++ N +SI+ + Sbjct: 248 LIVVNPTNPTSKEFDTNALNAIKQAVEKNPKLMIISDEVYGAFVP--NFKSIYSVVPYN- 304 Query: 296 VAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGF 329 M S+SK G TG RLG + +K ++ D Sbjct: 305 -TMLVYSYSKLFGCTGWRLGVIALNEKNVFDDNI 337 >2HOR-A nrPDB Length = 427 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 17/87 (19%) Query: 241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET 300 SPNNP G L+ A G +YD Y Y P + E++ + T Sbjct: 204 SPNNPEG----------LLRHAVIKGCKSIYDMVY--YWPHYTP---IKYKADEDILLFT 248 Query: 301 ASFSKYAGFTGVRLGWTVIPKKLLYSD 327 SK+ G +G R GW +I + +Y++ Sbjct: 249 --MSKFTGHSGSRFGWALIKDESVYNN 273 >4H51-A nrPDB Length = 420 Score = 32.0 bits (71), Expect = 0.66, Method: Compositional matrix adjust. Identities = 44/165 (26%), Positives = 67/165 (40%), Gaps = 19/165 (11%) Query: 159 VSDGAKCDISRLQVMFGSNVT-IAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMR 217 VS GAK L +F + T I + DP++P + ++ G N Y + + + Sbjct: 122 VSLGAKL----LTRVFDAETTPIYLSDPTWPNHYG---VVKAAGWKNICTYAYYDPKTVS 174 Query: 218 CTPENGFFPDLSTV--GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 E G D+ G I+ C+ +NPTG ++EQ ++ + +DSAY Sbjct: 175 LNFE-GMKKDILAAPDGSVFILHQCA-HNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAY 232 Query: 276 AMYMS-----DDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 Y S D +F G E + SFSK G R G Sbjct: 233 QGYASGSLDTDAYAARLFARRGIE--VLLAQSFSKNMGLYSERAG 275 >1COJ-A nrPDB Length = 212 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 379 IIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKT 420 I+IDT+ Y Y K PY+ F N +WDV E EK Sbjct: 160 IVIDTYEHAYYVDYKNKRPPYIDAFFKN-INWDVVNERFEKA 200 >3BWN-A nrPDB Length = 391 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 19/123 (15%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE 295 I SPNNP G RE + V + + +++D AY Y P I ++ Sbjct: 160 IELVTSPNNPDGT--IRETV---VNRPDDDEAKVIHDFAY--YWPHYTP-----ITRRQD 207 Query: 296 VAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGAL 355 + +FSK G G R+GW ++ K VAK I G S SQ Sbjct: 208 HDIMLFTFSKITGHAGSRIGWALVKDK-------EVAKKMVEYIIVNSIGVSKESQVRTA 260 Query: 356 ACL 358 L Sbjct: 261 KIL 263 >4RKC-A nrPDB Length = 398 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 7/93 (7%) Query: 228 LSTVGRTDIIFF--CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR 285 T+ + D++ C +NPTG TREQ ++ ++ I D AY + +D Sbjct: 166 FETLNKDDVLLLHPCC-HNPTGVDLTREQWDTVLNVIQERELIPFMDIAYQGF-GEDMDS 223 Query: 286 SIFEIPGAEEVAME---TASFSKYAGFTGVRLG 315 + I A ++ + + SFSK G R+G Sbjct: 224 DAYAIRKAVDMGLPLFVSNSFSKNLSLYGERVG 256 >4F5M-A nrPDB Length = 406 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 12/141 (8%) Query: 180 IAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPE-NGFFPDLSTVGRTDIIF 238 + V +PS+P + + G +V++Y + T + + L+ D++ Sbjct: 133 VWVSNPSWP---NHKSVFNSAG---LEVREYAYYDAENHTLDFDALINSLNEAQAGDVVL 186 Query: 239 F--CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS--DDNPRSIFEIPGAE 294 F C +NPTG T EQ L + + + G + ++D AY + +++ + Sbjct: 187 FHGCC-HNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAAMH 245 Query: 295 EVAMETASFSKYAGFTGVRLG 315 + + +S+SK G R+G Sbjct: 246 KELIVASSYSKNFGLYNERVG 266 >1QO0-A nrPDB Length = 385 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Query: 29 TRNACLPMAKRVNTCKCVATPQEKIEYKTKV-----SRNSNMSKLQAGYLFPEIARR 80 TR A +P+ +R + C TP E EY + + N N + L A YL R Sbjct: 87 TRKAVMPVVERADALLCYPTPYEGFEYSPNIVYGGPAPNQNSAPL-AAYLIRHYGER 142 >4WB0-B nrPDB Length = 414 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 8/89 (8%) Query: 232 GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS-----DDNPRS 286 G ++ C+ +NPTG ++EQ ++ + +DSAY Y S D Sbjct: 184 GSVFLLHQCA-HNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAAR 242 Query: 287 IFEIPGAEEVAMETASFSKYAGFTGVRLG 315 +F G E + SFSK G R G Sbjct: 243 LFARRGIE--VLLAQSFSKNMGLYSERAG 269 >4OC9-A nrPDB Length = 424 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 11/91 (12%) Query: 234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 T IFF S +NP A A E++ Q+ AKK+ + + D+ A P Sbjct: 146 TKAIFFESLSNPQIAIADIEKINQI---AKKHKIVSICDNTVAT--------PFLLQPFK 194 Query: 294 EEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 V + S SKY G LG +I +K L Sbjct: 195 HGVDVIVHSLSKYVSGQGTALGGALIERKDL 225 >3EUC-A nrPDB Length = 367 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 236 IIFFCSPNNPTGAAATREQLTQLVEFAKKN--GSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 I++ PNNPTG + +V A+ + S++V D AY + + + + Sbjct: 160 IVYLAYPNNPTGNLFDAADMEAIVRAAQGSVCRSLVVVDEAYQPFAQESWMSRLTDF--G 217 Query: 294 EEVAMETASFSKYAGFTGVRLGWT 317 + M T S G G+RLG+ Sbjct: 218 NLLVMRTVS---KLGLAGIRLGYV 238 >1E0T-A nrPDB Length = 470 Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust. Identities = 21/46 (45%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 192 DSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDII 237 D S+ GQT F TD GN E + T E GF DLS VG T ++ Sbjct: 82 DVSLKAGQTFTFTTDKSVIGNSEMVAVTYE-GFTTDLS-VGNTVLV 125 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3EI8-A nrPDB 579 e-165 4FL0-A nrPDB 471 e-133 3QGU-A nrPDB 450 e-127 3ASB-A nrPDB 374 e-104 1GDE-A nrPDB 330 1e-90 1J32-A nrPDB 322 2e-88 1O4S-A nrPDB 320 8e-88 2Z61-A nrPDB 320 8e-88 6F77-B nrPDB 319 2e-87 2X5D-A nrPDB 317 8e-87 1GC4-A nrPDB 315 2e-86 1XI9-A nrPDB 305 4e-83 4MY5-A nrPDB 300 7e-82 6F35-A nrPDB 297 5e-81 5WMH-A nrPDB 295 2e-80 5YHV-A nrPDB 283 9e-77 3H14-A nrPDB 275 2e-74 3DYD-A nrPDB 265 4e-71 3PDX-A nrPDB 263 9e-71 2O1B-A nrPDB 262 3e-70 1U08-A nrPDB 255 3e-68 3T32-A nrPDB 252 2e-67 1V2E-A nrPDB 251 4e-67 3ELE-A nrPDB 250 7e-67 4WP0-A nrPDB 249 1e-66 3FVS-A nrPDB 249 1e-66 3JTX-A nrPDB 248 4e-66 4IX8-A nrPDB 241 4e-64 2ZC0-A nrPDB 238 4e-63 3B1C-A nrPDB 236 2e-62 3AV7-A nrPDB 235 4e-62 1X0M-A nrPDB 233 1e-61 4CVQ-A nrPDB 232 2e-61 2DOU-A nrPDB 229 2e-60 4DQ6-A nrPDB 228 3e-60 2ZJG-A nrPDB 228 5e-60 3B46-A nrPDB 226 2e-59 1BW0-A nrPDB 223 1e-58 1YIY-A nrPDB 214 8e-56 1VP4-A nrPDB 210 1e-54 3EZS-A nrPDB 206 2e-53 3FDB-A nrPDB 205 5e-53 2ZYJ-A nrPDB 203 1e-52 3OP7-A nrPDB 199 2e-51 3DZZ-A nrPDB 195 4e-50 3TCM-A nrPDB 186 1e-47 5TON-A nrPDB 180 1e-45 3CQ5-A nrPDB 174 9e-44 3FTB-A nrPDB 159 3e-39 4M2J-A nrPDB 156 1e-38 4RAE-A nrPDB 154 7e-38 4R2N-A nrPDB 148 7e-36 1UU1-A nrPDB 143 1e-34 3FKD-A nrPDB 139 2e-33 1LC8-A nrPDB 132 2e-31 3GET-A nrPDB 132 3e-31 1YAA-A nrPDB 124 1e-28 6EZL-A nrPDB 121 5e-28 3P1T-A nrPDB 121 7e-28 1AY8-A nrPDB 119 2e-27 3LY1-A nrPDB 118 4e-27 5DJ3-A nrPDB 101 6e-22 Sequences not found previously or not previously below threshold: 1WST-A nrPDB 205 3e-53 2GB3-A nrPDB 203 2e-52 3L8A-A nrPDB 200 2e-51 2O0R-A nrPDB 198 5e-51 5Z0Q-C nrPDB 182 3e-46 3II0-A nrPDB 170 1e-42 1D2F-A nrPDB 166 1e-41 1C7O-A nrPDB 161 7e-40 1IAY-A nrPDB 156 1e-38 2CST-A nrPDB 151 4e-37 3IHJ-A nrPDB 150 1e-36 3NRA-A nrPDB 149 2e-36 1M4N-A nrPDB 148 6e-36 4GDY-A nrPDB 138 6e-33 3IF2-A nrPDB 132 2e-31 6HNB-A nrPDB 129 2e-30 1IJI-A nrPDB 128 6e-30 3HDO-A nrPDB 126 2e-29 3FFH-A nrPDB 119 2e-27 6HNV-A nrPDB 118 4e-27 4JE5-A nrPDB 118 6e-27 3PD6-B nrPDB 117 7e-27 3G7Q-A nrPDB 117 7e-27 3EUC-A nrPDB 115 5e-26 3RQ1-A nrPDB 115 5e-26 1TAR-A nrPDB 112 3e-25 4F5M-A nrPDB 111 6e-25 3FSL-A nrPDB 111 1e-24 3G0T-A nrPDB 110 1e-24 2ZY3-A nrPDB 106 2e-23 3FDD-A nrPDB 105 5e-23 2ZY2-A nrPDB 105 5e-23 4EMY-A nrPDB 104 8e-23 5X03-B nrPDB 101 5e-22 4N0B-A nrPDB 101 5e-22 4WB0-B nrPDB 101 6e-22 4W5K-A nrPDB 99 2e-21 3MEB-A nrPDB 99 3e-21 4WD2-A nrPDB 99 3e-21 2X5F-A nrPDB 99 4e-21 4H51-A nrPDB 99 4e-21 3F6T-A nrPDB 99 5e-21 4RKC-A nrPDB 94 1e-19 4WBT-A nrPDB 93 2e-19 4EFF-A nrPDB 84 8e-17 6C3C-A nrPDB 79 3e-15 3K7Y-A nrPDB 73 3e-13 5IWQ-A nrPDB 71 8e-13 3BWN-A nrPDB 69 3e-12 2HOR-A nrPDB 69 4e-12 4LW2-A nrPDB 62 4e-10 1M6S-A nrPDB 62 5e-10 2X8U-A nrPDB 56 3e-08 4W91-A nrPDB 56 3e-08 5C6U-A nrPDB 54 2e-07 4BMK-A nrPDB 53 3e-07 6CJB-A nrPDB 52 7e-07 1FC4-A nrPDB 51 8e-07 3VK2-A nrPDB 51 2e-06 4U1T-A nrPDB 50 3e-06 5I92-A nrPDB 49 6e-06 3QI6-A nrPDB 48 9e-06 4PIW-A nrPDB 48 9e-06 3DR4-A nrPDB 47 1e-05 5VMB-A nrPDB 47 2e-05 2DKJ-A nrPDB 46 5e-05 3WGB-A nrPDB 45 9e-05 4J5U-A nrPDB 44 1e-04 4L0O-H nrPDB 44 1e-04 5TXT-B nrPDB 44 1e-04 5LL2-A nrPDB 44 1e-04 3I5T-A nrPDB 44 2e-04 3WY7-A nrPDB 43 2e-04 3NYS-A nrPDB 43 2e-04 2C81-A nrPDB 43 3e-04 5W1B-A nrPDB 43 3e-04 2E7J-A nrPDB 43 3e-04 3ECD-A nrPDB 42 4e-04 1CS1-A nrPDB 42 5e-04 1IBJ-A nrPDB 42 6e-04 4K2M-A nrPDB 42 6e-04 3BB8-A nrPDB 42 7e-04 3N0L-A nrPDB 41 9e-04 1YJS-A nrPDB 41 0.001 6JEQ-A nrPDB 41 0.001 2OGE-A nrPDB 41 0.001 5IJG-A nrPDB 41 0.001 4P3M-A nrPDB 41 0.002 5KQU-A nrPDB 40 0.002 4IYO-A nrPDB 40 0.003 1QO0-A nrPDB 40 0.003 5KQT-A nrPDB 39 0.003 4WXB-A nrPDB 39 0.003 3GBX-A nrPDB 39 0.004 2GMS-A nrPDB 39 0.004 3GJU-A nrPDB 39 0.005 4GSA-A nrPDB 39 0.005 3GZD-A nrPDB 37 0.012 5KR6-A nrPDB 37 0.012 4BHD-A nrPDB 37 0.012 4OTL-A nrPDB 37 0.013 3AEO-A nrPDB 37 0.013 5WT2-A nrPDB 37 0.014 3NDN-A nrPDB 37 0.014 3G8M-A nrPDB 37 0.015 5KQW-A nrPDB 37 0.019 3UWC-A nrPDB 37 0.019 2C44-A nrPDB 36 0.045 5KR5-A nrPDB 36 0.056 2CB1-A nrPDB 35 0.086 5YZA-A nrPDB 35 0.087 3RUY-A nrPDB 34 0.10 2E8Y-A nrPDB 34 0.11 5W70-A nrPDB 34 0.16 6BXI-A nrPDB 34 0.16 5JNF-C nrPDB 34 0.17 5ES8-A nrPDB 34 0.17 5ES6-A nrPDB 34 0.17 3FCR-A nrPDB 34 0.17 4OBV-D nrPDB 34 0.19 3HMU-A nrPDB 34 0.20 6G4F-A nrPDB 33 0.23 5KR3-A nrPDB 33 0.24 4IRN-A nrPDB 33 0.30 3MAF-B nrPDB 32 0.43 5N3U-B nrPDB 32 0.59 5VIU-A nrPDB 32 0.66 1ULZ-A nrPDB 32 0.67 4C65-A nrPDB 32 0.68 5LH9-A nrPDB 32 0.74 1WA5-C nrPDB 31 0.83 6GIO-D nrPDB 31 1.0 5VNX-A nrPDB 31 1.1 5IJW-A nrPDB 31 1.4 3LGA-A nrPDB 31 1.5 5WGB-A nrPDB 31 1.5 4QGR-A nrPDB 30 2.1 6IO1-A nrPDB 30 2.2 3U9T-A nrPDB 30 2.3 4HDE-A nrPDB 30 2.5 3RI6-A nrPDB 30 2.5 4ISY-A nrPDB 29 3.1 4NZ0-A nrPDB 29 3.2 3RHA-A nrPDB 29 5.7 1FGS-A nrPDB 28 8.8 5O9Z-R nrPDB 28 8.9 4BA4-A nrPDB 28 9.4 >3EI8-A nrPDB Length = 432 Score = 579 bits (1492), Expect = e-165, Method: Composition-based stats. Identities = 425/426 (99%), Positives = 425/426 (99%) Query: 36 MAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVIS 95 MAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVIS Sbjct: 1 MAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVIS 60 Query: 96 LGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD 155 LGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD Sbjct: 61 LGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD 120 Query: 156 DVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 215 DVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY Sbjct: 121 DVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 180 Query: 216 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY Sbjct: 181 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 240 Query: 276 AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 335 AMYMSDDNPRSIFEIPGAEEVAMETASFS YAGFTGVRLGWTVIPKKLLYSDGFPVAKDF Sbjct: 241 AMYMSDDNPRSIFEIPGAEEVAMETASFSNYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 300 Query: 336 NRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK 395 NRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK Sbjct: 301 NRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK 360 Query: 396 NAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 455 NAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR Sbjct: 361 NAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 420 Query: 456 FKQLYK 461 FKQLYK Sbjct: 421 FKQLYK 426 >4FL0-A nrPDB Length = 456 Score = 471 bits (1211), Expect = e-133, Method: Composition-based stats. Identities = 257/410 (62%), Positives = 322/410 (78%) Query: 51 EKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVIT 110 +K+ TK+ RN N+ KL+ YLFPEI RR H+ K+P+ Q+ISLG GDTTEPIPE IT Sbjct: 30 KKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQIT 89 Query: 111 SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL 170 S M+ AH LST+EGY GYG EQG K LR AIA+TFY L + ++VFVSDGA+ DISRL Sbjct: 90 SHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL 149 Query: 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST 230 Q++ GSNVTIAVQDP++PAY+DSSVI+GQTG F+ +KY N+ YM C P N FFPDL+ Sbjct: 150 QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAM 209 Query: 231 VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 290 RTD+IFFCSPNNPTG A+R+QL QLV+FAK NGSII++DSAYA ++ D +PRSI+EI Sbjct: 210 TPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI 269 Query: 291 PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 PGA EVA+E +SFSK+AGFTGVRLGW++IP +LLYS+GFP+ DF+RI+ T FNGASNI+ Sbjct: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIA 329 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 QAG LACL+ GL+ + V +YKEN I++DT SLG VYGG NAPY+WVHF SW Sbjct: 330 QAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW 389 Query: 411 DVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 DVF EILE TH++T PGSGFGPGGE ++R+S FG R++I+EA +R + + Sbjct: 390 DVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFF 439 >3QGU-A nrPDB Length = 449 Score = 450 bits (1157), Expect = e-127, Method: Composition-based stats. Identities = 279/437 (63%), Positives = 335/437 (76%), Gaps = 3/437 (0%) Query: 25 FNLRTRNACLPMAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAH 84 N+R+ + + R V + V RN N KL+AGYLFPEIARRR AH Sbjct: 3 LNVRSTASGARSSTRSRRMTAVVQAVAQRAGTIDVQRNENFGKLRAGYLFPEIARRRKAH 62 Query: 85 LLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAK 144 K PDA++ISLGIGDTTEP+P+ I AMAK A L+T EGYSGYGAEQG LR A+A Sbjct: 63 QEKNPDAKIISLGIGDTTEPLPKYIADAMAKAAAGLATREGYSGYGAEQGQGALREAVAS 122 Query: 145 TFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFN 204 TFYG G D++F+SDG+KCDI+R+Q+MFGS T+AVQDPSYP YVD+SV+MG TG N Sbjct: 123 TFYGHAGRAADEIFISDGSKCDIARIQMMFGSKPTVAVQDPSYPVYVDTSVMMGMTGDHN 182 Query: 205 TDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKK 264 + IEYM C P+N FFPDLS RTDIIFFCSPNNPTGAAATR QLT+LV FA+K Sbjct: 183 GT--GFDGIEYMVCNPDNHFFPDLSKAKRTDIIFFCSPNNPTGAAATRAQLTELVNFARK 240 Query: 265 NGSIIVYDSAYAMYMSD-DNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKL 323 NGSI+VYD+AYA+Y+S+ D P++I+EIPGA+EVA+ET SFSKYAGFTGVRLGWTV+PK L Sbjct: 241 NGSILVYDAAYALYISNPDCPKTIYEIPGADEVAIETCSFSKYAGFTGVRLGWTVVPKAL 300 Query: 324 LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDT 383 Y++G PV D+NR++ TCFNGASNI QAG LACL PEGL+ M+ +I FYKEN I+ T Sbjct: 301 KYANGEPVHADWNRVMTTCFNGASNIVQAGGLACLQPEGLKEMNAMIKFYKENAQILKTT 360 Query: 384 FTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAF 443 FT +G+ VYGG +APY+WV FP + SWDVFAEILE+ ++VTTPGSG+GP GEGFVR SAF Sbjct: 361 FTEMGFSVYGGDDAPYIWVGFPGKPSWDVFAEILERCNIVTTPGSGYGPAGEGFVRASAF 420 Query: 444 GHRENILEACRRFKQLY 460 G RENILEA RRFK+ Y Sbjct: 421 GSRENILEAVRRFKEAY 437 >3ASB-A nrPDB Length = 400 Score = 374 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 162/402 (40%), Positives = 237/402 (58%), Gaps = 18/402 (4%) Query: 59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAH 118 + RN + L YLF ++ +R + L+ P VI+L IGDTT+P+ + A A Sbjct: 1 MKRNPHFVSLTKNYLFADLQKRVAQFRLENPQHTVINLSIGDTTQPLNASVAEAFASSIA 60 Query: 119 ELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNV 178 LS+ GYG + G LR +++ FY G + ++F+SDGAK D+ RL FG N Sbjct: 61 RLSSPTTCRGYGPDFGLPALRQKLSEDFYRGF-VDAKEIFISDGAKVDLFRLLSFFGPNQ 119 Query: 179 TIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIF 238 T+A+QDPSYPAY+D + + G I + C EN FFP+ DI+ Sbjct: 120 TVAIQDPSYPAYLDIARLTGAK-----------EIIALPCLQENAFFPEFPEDTHIDILC 168 Query: 239 FCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVA 297 CSPNNPTG ++QL +V +A ++ +I++D+AY+ ++SD + P+SIFEIP A A Sbjct: 169 LCSPNNPTGTVLNKDQLRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCA 228 Query: 298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC 357 +E SFSK GF G+RLGWTVIP++L Y+DG V +D+ R + T FNGAS +Q +A Sbjct: 229 IEINSFSKPLGFAGIRLGWTVIPQELTYADGHFVIQDWERFLSTTFNGASIPAQEAGVAG 288 Query: 358 LTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP--NQSSWDVFAE 415 L+ + I +Y+EN++++ + G++V+GG++APY+WV N S D+F Sbjct: 289 LSILPQL---EAIHYYRENSDLLRKALLATGFEVFGGEHAPYLWVKPTQANISDRDLFDF 345 Query: 416 ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFK 457 L + H+ TPG GFG G GFVR S+ G RE+IL AC R + Sbjct: 346 FLREYHIAITPGIGFGRSGSGFVRFSSLGKREDILAACERLQ 387 >1GDE-A nrPDB Length = 389 Score = 330 bits (845), Expect = 1e-90, Method: Composition-based stats. Identities = 90/379 (23%), Positives = 150/379 (39%), Gaps = 28/379 (7%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL 150 VISLGIG+ P+ I + + G + YG G LR AIA+ Sbjct: 26 KDVISLGIGEPDFDTPQHIKEYAKEALDK-----GLTHYGPNIGLLELREAIAEKLKKQN 80 Query: 151 GIGDD---DVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTD 206 GI D ++ V GA + L + + P++ +Y + ++ G + Sbjct: 81 GIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGKPV---E 137 Query: 207 VQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNG 266 V Y E+ E + +T + SP NPTGA T++ L ++ +F ++ Sbjct: 138 VPTYEEDEFRLNVDELKKY----VTDKTRALIINSPCNPTGAVLTKKDLEEIADFVVEHD 193 Query: 267 SIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLY 325 I++ D Y ++ DD SI + G E + FSK TG RLG+ P ++ Sbjct: 194 LIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFVAAPSWII- 252 Query: 326 SDGFPVAKDFNRIICTCFNGASNISQAGALACLTPE-GLEAMHKVIGFYKENTNIIIDTF 384 + + Q A L E +A+ ++ Y ++ Sbjct: 253 -------ERMVKFQMYNATCPVTFIQYAAAKALKDERSWKAVEEMRKEYDRRRKLVWKRL 305 Query: 385 TSLGYDVYGGKNAPYVWVHFPN--QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSA 442 +G K A Y++ + +S +L++ V PGS FG GEG+VR+S Sbjct: 306 NEMGLPTVKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAFGKAGEGYVRISY 365 Query: 443 FGHRENILEACRRFKQLYK 461 E + EA R +++ K Sbjct: 366 ATAYEKLEEAMDRMERVLK 384 >1J32-A nrPDB Length = 388 Score = 322 bits (825), Expect = 2e-88, Method: Composition-based stats. Identities = 83/387 (21%), Positives = 153/387 (39%), Gaps = 31/387 (8%) Query: 82 SAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAA 141 A +K V S G+ P+ I A +G + YG G LR A Sbjct: 21 KAKAMKAEGIDVCSFSAGEPDFNTPKHIVEAAKAALE-----QGKTRYGPAAGEPRLREA 75 Query: 142 IAKTFY--GGLGIGDDDVFVSDGAKCDISRLQ-VMFGSNVTIAVQDPSYPAYVDSSVIMG 198 IA+ GL G D++ V++G K I L M + + P + +Y + + Sbjct: 76 IAQKLQRDNGLCYGADNILVTNGGKQSIFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLAE 135 Query: 199 QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQL 258 T + + +PE + +T ++ F +P+NPTG T +++ + Sbjct: 136 GTPVILPTTVETQ----FKVSPEQIRQ---AITPKTKLLVFNTPSNPTGMVYTPDEVRAI 188 Query: 259 VEFAKKNGSIIVYDSAYAMYMSDDNPRSIF--EIPGAEEVAMETASFSKYAGFTGVRLGW 316 + A + G ++ D Y + DD P A E ++ + F+K TG R+G+ Sbjct: 189 AQVAVEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSVVCSGFAKTYAMTGWRVGF 248 Query: 317 TVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKEN 376 P P+ K +I + +Q GA+A + + +++ + E Sbjct: 249 LAGP--------VPLVKAATKIQGHSTSNVCTFAQYGAIAAY-ENSQDCVQEMLAAFAER 299 Query: 377 TNIIIDTFTSL-GYDVYGGKNAPYVWVHF--PNQSSWDVFAEILEKTHVVTTPGSGFGPG 433 ++D ++ G + A Y++ +SS D +E+L++ V T PG+ FG Sbjct: 300 RRYMLDALNAMPGLECPKPDGAFYMFPSIAKTGRSSLDFCSELLDQHQVATVPGAAFG-- 357 Query: 434 GEGFVRVSAFGHRENILEACRRFKQLY 460 + +R+S + I R ++ Sbjct: 358 ADDCIRLSYATDLDTIKRGMERLEKFL 384 >1O4S-A nrPDB Length = 389 Score = 320 bits (820), Expect = 8e-88, Method: Composition-based stats. Identities = 93/387 (24%), Positives = 145/387 (37%), Gaps = 40/387 (10%) Query: 82 SAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAA 141 A L VI+L G+ P PE + + + G Y +G LR Sbjct: 32 KAKALIKKGEDVINLTAGEPDFPTPEPVVEEAVRFLQK-----GEVKYTDPRGIYELREG 86 Query: 142 IAKTFYGGL--GIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMG 198 IAK I D V V++GAK + + + V P + +Y+ ++ G Sbjct: 87 IAKRIGERYKKDISPDQVVVTNGAKQALFNAFMALLDPGDEVIVFSPVWVSYIPQIILAG 146 Query: 199 QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATRE 253 T + + F P L V G+T + SPNNPTG RE Sbjct: 147 GT------------VNVVETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRRE 194 Query: 254 QLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVR 313 L LV AKK I+ D Y + D SI ++ + + FSK TG R Sbjct: 195 FLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFSKSHSMTGWR 254 Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY 373 +G+ + +K VA ++I + + ++Q AL L + ++ + Sbjct: 255 VGYLISSEK--------VATAVSKIQSHTTSCINTVAQYAALKALEVDN----SYMVQTF 302 Query: 374 KENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPG 433 KE N +++ +G + A Y++ +LE+ V PGS F Sbjct: 303 KERKNFVVERLKKMGVKFVEPEGAFYLFFKVRG-DDVKFCERLLEEKKVALVPGSAFLK- 360 Query: 434 GEGFVRVSAFGHRENILEACRRFKQLY 460 GFVR+S E + EA R + Sbjct: 361 -PGFVRLSFATSIERLTEALDRIEDFL 386 >2Z61-A nrPDB Length = 370 Score = 320 bits (820), Expect = 8e-88, Method: Composition-based stats. Identities = 88/404 (21%), Positives = 153/404 (37%), Gaps = 42/404 (10%) Query: 60 SRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHE 119 R N + + A L+ +VI L IG+ P+ I K Sbjct: 4 KRLLNFESFEVMDILAL------AQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLK- 56 Query: 120 LSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL--GIGDDDVFVSDGAKCDIS-RLQVMFGS 176 EG + Y +G LR I++ + I D++ ++ G+ + L + Sbjct: 57 ----EGKTHYTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDD 112 Query: 177 NVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI 236 + +Q+P YP Y + +G F ++ + E +T Sbjct: 113 GDEVLIQNPCYPCYKNFIRFLGAKPVF---------CDFTVESLEEAL------SDKTKA 157 Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEV 296 I SP+NP G RE + EFA +N I+ D Y + + S E E Sbjct: 158 IIINSPSNPLGEVIDRE----IYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEK 213 Query: 297 AMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALA 356 + FSK TG R+G+ + +++ + ++ F A ISQ AL Sbjct: 214 TILINGFSKLYAMTGWRIGYVISNDEII--------EAILKLQQNLFISAPTISQYAALK 265 Query: 357 CLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEI 416 E ++ +I + +++ G++V A YV+ + + + ++ Sbjct: 266 AFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNI-GEDGREFAYKL 324 Query: 417 LEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 L++ V TPG GFG G+ ++R+S ENI E R K+ Sbjct: 325 LKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEGLERIKEFL 368 >6F77-B nrPDB Length = 400 Score = 319 bits (817), Expect = 2e-87, Method: Composition-based stats. Identities = 93/404 (23%), Positives = 147/404 (36%), Gaps = 42/404 (10%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQG 134 IA + A LK VI LG G+ P+ I A G + Y G Sbjct: 15 ATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKKAAIDAIDR-----GETKYTPVSG 69 Query: 135 AKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYV 191 LR AIAK F L V G K + + + P + +Y Sbjct: 70 IPELREAIAKKFKRENNLDYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYP 129 Query: 192 DSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAAT 251 + + G T F Q+ + E+ D + +T F SP+NP+GAA + Sbjct: 130 EMVALCGGTPVFVPTRQE----NNFKLKAED---LDRAITPKTKWFVFNSPSNPSGAAYS 182 Query: 252 REQLTQLVEFAKKNGSIIVY-DSAYAMYMSDD-NPRSIFEI-PGAEEVAMETASFSKYAG 308 E+L L + K+ + V D Y D + E+ PG E + SK Sbjct: 183 HEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVSKAYA 242 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHK 368 TG R+G+ P L+ K + I +GA++I+Q A+ L + + + Sbjct: 243 MTGWRIGYAAGPLHLI--------KAMDMIQGQQTSGAASIAQWAAVEALN-GPQDFIGR 293 Query: 369 VIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWVHFPN------------QSSWDVFAE 415 ++ ++++ G + A YV+ ++ D +E Sbjct: 294 NKEIFQGRRDLVVSMLNQAKGISCPTPEGAFYVYPSCAGLIGKTAPSGKVIETDEDFVSE 353 Query: 416 ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 +LE V GS FG G R+S + EACRR ++ Sbjct: 354 LLETEGVAVVHGSAFGLGPN--FRISYATSEALLEEACRRIQRF 395 >2X5D-A nrPDB Length = 412 Score = 317 bits (811), Expect = 8e-87, Method: Composition-based stats. Identities = 95/404 (23%), Positives = 169/404 (41%), Gaps = 41/404 (10%) Query: 72 YLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGA 131 Y+F A + A + +I L +G+ P P I + A E GY Sbjct: 20 YVFNITAELKMAARRR--GEDIIDLSMGNPDGPTPPHIVEKLCTVAQR----EDTHGYST 73 Query: 132 EQGAKPLRAAIAKTFYGGLGIGDD---DVFVSDGAKCDISRLQ-VMFGSNVTIAVQDPSY 187 +G LR AI+ + + D + V+ G+K ++ L TI V +PSY Sbjct: 74 SRGIPRLRRAISHWYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATLDHGDTILVPNPSY 133 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST-----VGRTDIIFFCSP 242 P ++ +VI G + + P FF +L + + ++ P Sbjct: 134 PIHIYGAVIAGA------------QVRSVPLVPGIDFFNELERAIRESIPKPRMMILGFP 181 Query: 243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAMETA 301 +NPT + ++V AK+ ++V+D AYA + D SI ++PGA+++A+E Sbjct: 182 SNPTAQCVELDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF 241 Query: 302 SFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPE 361 + SK G R+G+ V +L+ + RI G Q A+A L Sbjct: 242 TLSKSYNMAGWRIGFMVGNPELVSA--------LARIKSYHDYGTFTPLQVAAIAAL-EG 292 Query: 362 GLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPN----QSSWDVFAEIL 417 + + + Y++ ++++ G+ V K + YVW P S + ++L Sbjct: 293 DQQCVRDIARQYQQRRDVLVKGLREAGWMVENPKASMYVWAKIPEPYAHLGSLEFAKKLL 352 Query: 418 EKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 + V +PG GFG G+ VR + +R+ + +A R K +++ Sbjct: 353 QDAKVSVSPGIGFGDYGDDHVRFALIENRDRLRQAVRGIKAMFR 396 >1GC4-A nrPDB Length = 385 Score = 315 bits (808), Expect = 2e-86, Method: Composition-based stats. Identities = 90/397 (22%), Positives = 148/397 (37%), Gaps = 40/397 (10%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQG 134 +A A L+ +++L G+ PE + A + +G + Y G Sbjct: 15 AVVAVNAKALELRRQGVDLVALTAGEPDFDTPEHVKEAARRALA-----QGKTKYAPPAG 69 Query: 135 AKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYV 191 LR A+A+ F GL + ++ V+ G + L Q + + V P + +Y Sbjct: 70 IPELREALAEKFRRENGLSVTPEETIVTVGGSQALFNLFQAILDPGDEVIVLSPYWVSYP 129 Query: 192 DSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPT 246 + G G + + PE GF PD V RT + SPNNPT Sbjct: 130 EMVRFAG------------GVVVEVETLPEEGFVPDPERVRRAITPRTKALVVNSPNNPT 177 Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKY 306 GA +E L L A ++ +V D Y + + S + A E + +K Sbjct: 178 GAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGRV--APEHTLTVNGAAKA 235 Query: 307 AGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT--PEGLE 364 TG R+G+ PK+++ K + I+Q L LT Sbjct: 236 FAMTGWRIGYACGPKEVI--------KAMASVSRQSTTSPDTIAQWATLEALTNQEASRA 287 Query: 365 AMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQS-SWDVFAEILEKTHVV 423 + Y+ +++++ T+LG A YV + + AE L + V Sbjct: 288 FVEMAREAYRRRRDLLLEGLTALGLKAVRPSGAFYVLMDTSPIAPDEVRAAERLLEAGVA 347 Query: 424 TTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 PG+ F G VR+S EN+ +A RF ++ Sbjct: 348 VVPGTDFAAFG--HVRLSYATSEENLRKALERFARVL 382 >1XI9-A nrPDB Length = 406 Score = 305 bits (780), Expect = 4e-83, Method: Composition-based stats. Identities = 95/396 (23%), Positives = 151/396 (38%), Gaps = 41/396 (10%) Query: 83 AHLLKYPDAQVISLGIGDT---TEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLR 139 A L+ +VI L IGD PE + A K EG++ YG +G LR Sbjct: 30 ARELEKKGIKVIRLNIGDPVKFDFQPPEHMKEAYCKAIK-----EGHNYYGDSEGLPELR 84 Query: 140 AAIAK--TFYGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVI 196 AI + G+ I DDV V+ + + + I V PSYP Y Sbjct: 85 KAIVEREKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILVPGPSYPPYTGLVKF 144 Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAAT 251 G R E + PD+ + RT I +PNNPTGA Sbjct: 145 YGGKPV------------EYRTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYD 192 Query: 252 REQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTG 311 ++ L +++ A + ++ D Y + + S + + + SK TG Sbjct: 193 KKTLEEILNIAGEYEIPVISDEIYDLMTYEGEHISPGSL-TKDVPVIVMNGLSKVYFATG 251 Query: 312 VRLGWT--VIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKV 369 RLG+ V P+ L V + +R+ + +Q A+A LT ++ + + Sbjct: 252 WRLGYMYFVDPENKLSE----VREAIDRLARIRL-CPNTPAQFAAIAGLT-GPMDYLKEY 305 Query: 370 IGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWVHF---PNQSSWDVFAEILEKTHVVTT 425 + KE + I + G + A Y++ P ++ + ++L HV+ Sbjct: 306 MKKLKERRDYIYKRLNEIPGISTTKPQGAFYIFPKIEVGPWKNDKEFVLDVLHNAHVLFV 365 Query: 426 PGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 GSGFG G G R E + EA RF++ K Sbjct: 366 HGSGFGEYGAGHFRAVFLPPIEILEEAMDRFEKFMK 401 >4MY5-A nrPDB Length = 393 Score = 300 bits (769), Expect = 7e-82, Method: Composition-based stats. Identities = 88/407 (21%), Positives = 150/407 (36%), Gaps = 34/407 (8%) Query: 62 NSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELS 121 N N++K++ + R+ + PD V+ L +G+ P+ I A + Sbjct: 10 NKNLNKIEVSMI-----RQFDQSISDIPD--VLKLTLGEPDFATPKHIKEAAKRAIDAD- 61 Query: 122 TIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG---DDDVFVSDGAKCDISR-LQVMFGSN 177 S Y G LR A + + D+++ V+ GA +S L + Sbjct: 62 ----ESHYTGMAGLLALRQAASAFVKEKYHLTYNPDNEILVTIGATEALSASLTAILEPG 117 Query: 178 VTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDII 237 + + P+YP Y ++G V+ TPE L + Sbjct: 118 DKVLLPAPAYPGYEPVVNLVGA-----EVVEIDTRSNDFVLTPEMLEEAILKEGEALKAV 172 Query: 238 FFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVA 297 P NPTG +R+Q+ L E KK ++ D YA + Sbjct: 173 ILNYPTNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYAELTYTGESHVSIA-EYLPDQT 231 Query: 298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC 357 + + SK TG RLG P L + K ++ A+ Q A+ Sbjct: 232 ILISGLSKSHAMTGWRLGLIFAPAVLTAQ----LIKSHQYLVT----AATTSVQFAAIEA 283 Query: 358 LTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP---NQSSWDVFA 414 LT +A+ + Y + + II+ ++ + + A Y++ P Q S+ Sbjct: 284 LTNGKDDAL-PMKEEYIKRRDYIIEKMEAMKFKIIKPDGAFYIFAKIPVAQGQDSFKFLQ 342 Query: 415 EILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 + ++ V PG FG GEG++R+S E I EA +R K+ + Sbjct: 343 DFAKEKAVAFIPGVAFGKYGEGYLRISYAASMETIKEAMKRLKEFME 389 >6F35-A nrPDB Length = 410 Score = 297 bits (761), Expect = 5e-81, Method: Composition-based stats. Identities = 82/395 (20%), Positives = 142/395 (35%), Gaps = 42/395 (10%) Query: 82 SAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAA 141 A +K VI LG G+ PE + A + H G + Y A G L+ A Sbjct: 32 RAAAMKREGKPVIILGAGEPDFDTPEHVKQAASDAIHR-----GETKYTALDGTPELKKA 86 Query: 142 IAKTFY--GGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMG 198 I + F GL D++ V+ GAK + + + + P + +Y D I Sbjct: 87 IREKFQRENGLAYELDEITVATGAKQILFNAMMASLDPGDEVIIPTPYWTSYSDIVHICE 146 Query: 199 QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQL 258 + + + RT + SP+NP+GAA + L Sbjct: 147 GKPVLIA-------CDASSGFRLTAEKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPL 199 Query: 259 VEFAKKNGS-IIVYDSAYAMYMSDDNP--RSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 +E ++ ++ D Y + D PG + + SK TG R+G Sbjct: 200 LEVLLRHPHVWLLVDDMYEHIVYDGFRFVTPAQLEPGLKNRTLTVNGVSKAYAMTGWRIG 259 Query: 316 WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKE 375 + P++L+ K + + S+ISQA ++ L + + + ++ Sbjct: 260 YAGGPRELI--------KAMAVVQSQATSCPSSISQAASVVALN-GPQDFLKERTESFQR 310 Query: 376 NTNIIIDTFTSL-GYDVYGGKNAPYVWVHFPN------------QSSWDVFAEILEKTHV 422 +++++ ++ G D + A Y + ++ D A +LE HV Sbjct: 311 RRDLVVNGLNAIDGLDCRVPEGAFYTFSGCAGVLGKVTPSGKRIKTDTDFCAYLLEDAHV 370 Query: 423 VTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFK 457 PGS FG F R+S + EA R Sbjct: 371 AVVPGSAFGLSP--FFRISYATSEAELKEALERIA 403 >5WMH-A nrPDB Length = 475 Score = 295 bits (756), Expect = 2e-80, Method: Composition-based stats. Identities = 84/436 (19%), Positives = 164/436 (37%), Gaps = 55/436 (12%) Query: 51 EKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVIT 110 E + +S + + L+ + A L VI L G+ P+V+ Sbjct: 62 ETLSSSVDMSLSPRVQSLKPS---KTMVITDLAATLVQSGVPVIRLAAGEPDFDTPKVVA 118 Query: 111 SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKCDI- 167 A EG++ Y G LR AI + GL D + VS+GAK + Sbjct: 119 EAGINAIR-----EGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAKQSLL 173 Query: 168 SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPD 227 + + + + P + +Y + + + T + N F D Sbjct: 174 QAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVV------------IPTKISNNFLLD 221 Query: 228 LSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNG-SIIVYDSAYAMYMSD 281 + ++ ++ CSP+NPTG+ + L ++ K+ +++ D Y + Sbjct: 222 PKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVLSDEIYEHIIYA 281 Query: 282 DNPRSIFE-IPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIIC 340 + F +P E + FSK TG RLG+ PK ++ + +++ Sbjct: 282 PATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLAGPKHIVAA--------CSKLQG 333 Query: 341 TCFNGASNISQAGALAC--LTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVYGGKNA 397 +GAS+I+Q +A L G E + +++ Y+E + ++ + + G + + A Sbjct: 334 QVSSGASSIAQKAGVAALGLGKAGGETVAEMVKAYRERRDFLVKSLGDIKGVKISEPQGA 393 Query: 398 PYVWVHFPNQ------------SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGH 445 Y+++ F S + L+K V PG FG + +R+S Sbjct: 394 FYLFIDFSAYYGSEAEGFGLINDSSSLALYFLDKFQVAMVPGDAFG--DDSCIRISYATS 451 Query: 446 RENILEACRRFKQLYK 461 + + A + ++ + Sbjct: 452 LDVLQAAVEKIRKALE 467 >5YHV-A nrPDB Length = 394 Score = 283 bits (724), Expect = 9e-77, Method: Composition-based stats. Identities = 90/394 (22%), Positives = 149/394 (37%), Gaps = 37/394 (9%) Query: 74 FPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQ 133 F + +A + +++L G + PE + +A A H GY Sbjct: 20 FYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQL-----GYSVAL 74 Query: 134 GAKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSYPAY 190 G LR AIA + G+ + D V ++ G+ + F + +A+ P YP Y Sbjct: 75 GIPELRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCY 134 Query: 191 VDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI----IFFCSPNNPT 246 + +G + + C P+ F P + D + SP NPT Sbjct: 135 RNILSALG------------CEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPT 182 Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKY 306 G E+L + + + ++ D Y + P++ + A+ SFSKY Sbjct: 183 GTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRN-AVVVNSFSKY 241 Query: 307 AGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 TG RLGW ++P L + + + +SQ A++ TPE Sbjct: 242 YAMTGWRLGWLLVPTVL--------RRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEA 293 Query: 367 HKVIGFYKENTNIIIDTFTSLGYDVYGG-KNAPYVWVHFPNQSSW--DVFAEILEKTHVV 423 + Y N ++++D +G D A YV+ + +S +++L T V Sbjct: 294 DGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVA 353 Query: 424 TTPGSGFGPG-GEGFVRVSAFGHRENILEACRRF 456 PG F G FVR+S G +I EA RR Sbjct: 354 IAPGIDFDTARGGSFVRISFAGPSGDIEEALRRI 387 >3H14-A nrPDB Length = 391 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 88/397 (22%), Positives = 146/397 (36%), Gaps = 39/397 (9%) Query: 74 FPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQ 133 F + +A + ++I + +G P A+AK + GY Sbjct: 14 FIVMDVMEAARRAEEAGRRIIHMEVGQPGTGAPRGAVEALAKSLETDAL-----GYTVAL 68 Query: 134 GAKPLRAAIAKTFYGGLGIGDD--DVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSYPAY 190 G LR IA+ + G+ D V ++ G+ + +F S + + P YP+Y Sbjct: 69 GLPALRQRIARLYGEWYGVDLDPGRVVITPGSSGGFLLAFTALFDSGDRVGIGAPGYPSY 128 Query: 191 VDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI--IFFCSPNNPTGA 248 +G + PEN P + D+ + SP NPTG Sbjct: 129 RQILRALGLVPV------------DLPTAPENRLQPVPADFAGLDLAGLMVASPANPTGT 176 Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 + L+E A+ G+ + D Y + + E+ + SFSKY Sbjct: 177 MLDHAAMGALIEAAQAQGASFISDEIYHGIEYEAKAVTALEL---TDECYVINSFSKYFS 233 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHK 368 TG R+GW V+P+ D V + + + C AS ++ A + + Sbjct: 234 MTGWRVGWMVVPE-----DQVRVVERIAQNMFICAPHASQVAALAA-----LDCDAELQA 283 Query: 369 VIGFYKENTNIIIDTFTSLGY-DVYGGKNAPYVWVHFPNQSSW--DVFAEILEKTHVVTT 425 + YK N ++++ G+ + A YV+ + + AEILEK V T Sbjct: 284 NLDVYKANRKLMLERLPKAGFTRIAPPDGAFYVYADVSDLTDDSRAFAAEILEKAGVAVT 343 Query: 426 PGSGFGPG-GEGFVRVSAFGHRENILEACRRFKQLYK 461 PG F P G G +R S +I E R + + Sbjct: 344 PGLDFDPERGAGTLRFSYARATADIEEGLDRLEAFMQ 380 >3DYD-A nrPDB Length = 427 Score = 265 bits (676), Expect = 4e-71, Method: Composition-based stats. Identities = 85/418 (20%), Positives = 143/418 (34%), Gaps = 41/418 (9%) Query: 60 SRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTE----PIPEVITSAMAK 115 R S+M+K P A + + P+ +ISL IGD T P +T AM Sbjct: 26 VRPSDMAKKTFN---PIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKD 82 Query: 116 KAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLG-IGDDDVFVSDGAKCDISRLQVMF 174 Y+GY G R IA ++ + DV ++ G I + Sbjct: 83 ALD----SGKYNGYAPSIGFLSSREEIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVL 138 Query: 175 -GSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVG- 232 I V P + Y + MG ++ PE + DL + Sbjct: 139 ANPGQNILVPRPGFSLYKTLAESMG------------IEVKLYNLLPEKSWEIDLKQLEY 186 Query: 233 ----RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIF 288 +T + +P+NP G+ ++ L +++ A + I+ D Y + D Sbjct: 187 LIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPL 246 Query: 289 EIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASN 348 + + +K G RLGW +I + +D + G Sbjct: 247 ATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDR--RDIFGNEIRDGLVKLSQRILGPCT 304 Query: 349 ISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWV----- 402 I Q + L E H + F K N ++ ++ G A Y+ V Sbjct: 305 IVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEME 364 Query: 403 HFPN-QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 HFP ++ + ++ + V P + F F+RV +LEAC R ++ Sbjct: 365 HFPEFENDVEFTERLVAEQSVHCLPATCF--EYPNFIRVVITVPEVMMLEACSRIQEF 420 >3PDX-A nrPDB Length = 402 Score = 263 bits (673), Expect = 9e-71, Method: Composition-based stats. Identities = 81/416 (19%), Positives = 139/416 (33%), Gaps = 38/416 (9%) Query: 62 NSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTE----PIPEVITSAMAKKA 117 N S + P A + + P+ VISL IGD T P +T AM Sbjct: 2 NVRPSDMSNKTFNPIRAIVDNMKVKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDAL 61 Query: 118 HELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLG-IGDDDVFVSDGAKCDISRLQVMF-G 175 Y+GY G R +A ++ + DV ++ G I + Sbjct: 62 D----SGKYNGYAPSIGYLSSREEVASYYHCPEAPLEAKDVILTSGCSQAIELCLAVLAN 117 Query: 176 SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVG--- 232 I + P + Y + MG ++ PE + DL + Sbjct: 118 PGQNILIPRPGFSLYRTLAESMG------------IEVKLYNLLPEKSWEIDLKQLESLI 165 Query: 233 --RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 290 +T + +P+NP G+ ++ L +++ A++ I+ D Y + D Sbjct: 166 DEKTACLVVNNPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMAT 225 Query: 291 PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 + +K G RLGW +I + +D + G I Sbjct: 226 LSTNVPILSCGGLAKRWLVPGWRLGWILIHDR--RDIFGNEIRDGLVKLSQRILGPCTIV 283 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWV-----HF 404 Q + L E + F K N ++ +++ G A Y+ V HF Sbjct: 284 QGALKSILQRTPQEFYQDTLSFLKSNADLCYGALSAIPGLQPVRPSGAMYLMVGIEMEHF 343 Query: 405 PN-QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 P ++ + ++ + V P + F F RV +LEAC R ++ Sbjct: 344 PEFENDVEFTERLIAEQSVHCLPATCF--EYPNFFRVVITVPEVMMLEACSRIQEF 397 >2O1B-A nrPDB Length = 404 Score = 262 bits (669), Expect = 3e-70, Method: Composition-based stats. Identities = 82/406 (20%), Positives = 151/406 (37%), Gaps = 26/406 (6%) Query: 59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAH 118 V R S+M + + + +++ +I++ +G P P+ I K Sbjct: 15 VPRGSHMISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKAL- 73 Query: 119 ELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGI---GDDDVFVSDGAKCDISRLQVM-F 174 TI YGA G + + AI + + +D+V + G K + + Sbjct: 74 ---TIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGLVAVPTCVI 130 Query: 175 GSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRT 234 + + DP Y Y+ ++ + ++ + D + +T Sbjct: 131 NPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKV--------DSQIIDKT 182 Query: 235 DIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE 294 +I+ PNNPTG+ AT+E + + K + IV+D AY + D SI + Sbjct: 183 KLIYLTYPNNPTGSTATKEVFDEAIAKFKGTDTKIVHDFAYGAFGFDAKNPSILASENGK 242 Query: 295 EVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGA 354 +VA+E S SK +G R+G+ V K ++ + + G Q A Sbjct: 243 DVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQA--------LKKYQTHTNAGMFGALQDAA 294 Query: 355 LACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFA 414 + L + + + +K + K YVW+ P + F Sbjct: 295 IYALN-HYDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFE 353 Query: 415 EIL-EKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 + L ++ ++ PG FG G +VR+S + + EA R +L Sbjct: 354 QFLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTEL 399 >1U08-A nrPDB Length = 386 Score = 255 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 73/390 (18%), Positives = 141/390 (36%), Gaps = 48/390 (12%) Query: 88 YPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFY 147 Q I+L G P + + AH ++ +G + Y G + LR AIA+ Sbjct: 27 AQQHQAINLSQGFPDFDGPRYLQE---RLAHHVA--QGANQYAPMTGVQALREAIAQKTE 81 Query: 148 GGLGIGDD---DVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMG----- 198 G D D+ V+ GA + + + + + + DPSY +Y + + G Sbjct: 82 RLYGYQPDADSDITVTAGATEALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKR 141 Query: 199 ---QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQL 255 Q F D Q++ + RT ++ +P+NP+ + Sbjct: 142 MALQPPHFRVDWQEFAAL----------------LSERTRLVILNTPHNPSATVWQQADF 185 Query: 256 TQLVEFAKKNGSIIVYDSAYAMY-MSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRL 314 L + + ++ D Y S S+ P E A+ +SF K TG ++ Sbjct: 186 AALWQAIAGHEIFVISDEVYEHINFSQQGHASVLAHPQLRERAVAVSSFGKTYHMTGWKV 245 Query: 315 GWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYK 374 G+ V P P++ + ++ + +Q L E + + FY+ Sbjct: 246 GYCVAPA--------PISAEIRKVHQYLTFSVNTPAQLALADMLRAEPEHYL-ALPDFYR 296 Query: 375 ENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWD---VFAEILEKTHVVTTPGSGF- 430 + +I+++ ++ + ++ V + S+ D + ++ V P S F Sbjct: 297 QKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDDVEFCQWLTQEHGVAAIPLSVFC 356 Query: 431 -GPGGEGFVRVSAFGHRENILEACRRFKQL 459 P +R+ +L A R +QL Sbjct: 357 ADPFPHKLIRLCFAKKESTLLAAAERLRQL 386 >3T32-A nrPDB Length = 383 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 79/398 (19%), Positives = 148/398 (37%), Gaps = 28/398 (7%) Query: 73 LFPEIARRRSAHLLKY---PDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGY 129 LF + RR H +K+ + ++I I D +P+ I +A+ K+ I GY+ Sbjct: 3 LFHKTVNRRGTHSIKWDTYKNEELIHAWIADMDFEVPQPIQTALKKRIEH--PIFGYTLP 60 Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYP 188 G + K Y I + + S G +S +Q N ++ VQ P YP Sbjct: 61 PENIGD--IICNWTKKQYNW-DIQKEWIVFSAGIVPALSTSIQAFTKENESVLVQPPIYP 117 Query: 189 AYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGA 248 + + V + +QK + + F ++ CSP+NP G Sbjct: 118 PFFEM-VTTNNRQLCVSPLQKQNDTYAIDFEHLEKQF-----QQGVKLMLLCSPHNPIGR 171 Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE--VAMETASFSKY 306 +E+LT+L K I+V D ++ + D+ + F E + + SK Sbjct: 172 VWKKEELTKLGSLCTKYNVIVVADEIHSDIIYADHTHTPFASLSEELAARTITCMAPSKT 231 Query: 307 AGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 G++ +IP + L + F I NI A+ E + + Sbjct: 232 FNIAGLQASIIIIPNEKL-------RQAFTSIQYRQGFHGLNIFAYTAMQSAYTECNDWL 284 Query: 367 HKVIGFYKENTNIIIDTFTSLG--YDVYGGKNAPYVWVHFP--NQSSWDVFAEILEKTHV 422 +++ + ++N + V + + +W+ N S + + EK + Sbjct: 285 NEIRFYIEDNAKFACEYIKDHIPTLSVMKPEGSFLLWIDCSALNLSQDERTKLLEEKGKI 344 Query: 423 VTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 + PG +G GGE + ++ R + E R + + Sbjct: 345 IVEPGEKYGLGGEEHIGINIGCPRSVLEEILNRLRHTF 382 >1V2E-A nrPDB Length = 381 Score = 251 bits (641), Expect = 4e-67, Method: Composition-based stats. Identities = 83/375 (22%), Positives = 138/375 (36%), Gaps = 44/375 (11%) Query: 94 ISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG 153 ++LG G + P P + A+ + Y G LR A+A+ F + Sbjct: 28 VNLGQGFPSNPPPPFLLEAVRRAL------GRQDQYAPPAGLPALREALAEEF----AVE 77 Query: 154 DDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGN 212 + V V+ GA + LQ + G + V +P + Y+ + + G Sbjct: 78 PESVVVTSGATEALYVLLQSLVGPGDEVVVLEPFFDVYLPDAFLAGAK----------AR 127 Query: 213 IEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGS 267 + + TPE GF DLS + RT + +P NPTG +L + A+ + Sbjct: 128 LVRLDLTPE-GFRLDLSALEKALTPRTRALLLNTPMNPTGLVFGERELEAIARLARAHDL 186 Query: 268 IIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD 327 ++ D Y + PR + E A E S K TG R+GW V PK+ + Sbjct: 187 FLISDEVYDELYYGERPRRLREF--APERTFTVGSAGKRLEATGYRVGWIVGPKEFMPRL 244 Query: 328 GFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGF-YKENTNIIIDTFTS 386 T F+ A QAG L E ++ + Y+ +++ + Sbjct: 245 A-------GMRQWTSFS-APTPLQAGVAEALKLARREGFYEALREGYRRRRDLLAGGLRA 296 Query: 387 LGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGE--GFVRVSAFG 444 +G VY + ++ P WD F ++E+ V P S F R + Sbjct: 297 MGLRVYVPEGTYFLMAELPG---WDAF-RLVEEARVALIPASAFYLEDPPKDLFRFAFCK 352 Query: 445 HRENILEACRRFKQL 459 E + A R ++ Sbjct: 353 TEEELHLALERLGRV 367 >3ELE-A nrPDB Length = 398 Score = 250 bits (639), Expect = 7e-67, Method: Composition-based stats. Identities = 83/396 (20%), Positives = 151/396 (38%), Gaps = 34/396 (8%) Query: 76 EIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGA 135 E ++R+A + K V IG+ + P P+++ + + + ++ GY + QG Sbjct: 23 EYGKKRAAIVGK---ENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSV-ALHGYTSAQGD 78 Query: 136 KPLRAAIAKTFYG--GLGIGDDDVFVSDGAKCDISRLQVMFGSN--VTIAVQDPSYPAYV 191 RAAIA+ G D+++++ GA +S S+ P +P Y Sbjct: 79 VETRAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYK 138 Query: 192 DSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAAT 251 G ++ I++ T + SPNNP+G + Sbjct: 139 VFVNAAGARLVEVPADTEHFQIDFDALEE--------RINAHTRGVIINSPNNPSGTVYS 190 Query: 252 REQLTQLVEFAKK------NGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSK 305 E + +L + +K I+ D Y + D + + S+SK Sbjct: 191 EETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPFVT--KYYDNTLVCYSYSK 248 Query: 306 YAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEA 365 G R+G+ ++P ++ Y A + A ++ Q + C G Sbjct: 249 SLSLPGERIGYVLVPDEV-YDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQGATGD-- 305 Query: 366 MHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTT 425 I YKEN +++ + T +GY + A Y++V + F E ++ V+ Sbjct: 306 ----INAYKENRDLLYEGLTRIGYHCFKPDGAFYMFVKALE-DDSNAFCEKAKEEDVLIV 360 Query: 426 PGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 GFG G+VR+S RE I + F+++YK Sbjct: 361 AADGFG--CPGWVRISYCVDREMIKHSMPAFEKIYK 394 >4WP0-A nrPDB Length = 472 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 70/403 (17%), Positives = 133/403 (33%), Gaps = 48/403 (11%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL 150 V++LG G P P+ A H +S + Y G PL +A F L Sbjct: 28 HDVVNLGQGFPDFPPPDFAVEAFQ---HAVSGDFMLNQYTKTFGYPPLTKILASFFGELL 84 Query: 151 GIGDD---DVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTD 206 G D +V V+ G + Q + + + +P + Y +++ G F + Sbjct: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS- 143 Query: 207 VQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEF 261 K G I+ + + D + RT + +PNNP G +RE+L + Sbjct: 144 -LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 Query: 262 AKKNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIP 320 +++ + + D Y + D + SI +PG E + S K TG ++GW + P Sbjct: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 Query: 321 KKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY------K 374 ++ K + SQA E L F + Sbjct: 263 DHIM--------KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 Query: 375 ENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ--------------SSWDVFAEILEKT 420 + +I + S+G + + ++ + +++ Sbjct: 315 RCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNK 374 Query: 421 HVVTTPGSGFGPGG-----EGFVRVSAFGHRENILEACRRFKQ 458 +V P S F + ++R + + ++ Sbjct: 375 GLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 >3FVS-A nrPDB Length = 422 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 70/403 (17%), Positives = 133/403 (33%), Gaps = 48/403 (11%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL 150 V++LG G P P+ A H +S + Y G PL +A F L Sbjct: 28 HDVVNLGQGFPDFPPPDFAVEAFQ---HAVSGDFMLNQYTKTFGYPPLTKILASFFGELL 84 Query: 151 GIGDD---DVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTD 206 G D +V V+ G + Q + + + +P + Y +++ G F + Sbjct: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS- 143 Query: 207 VQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEF 261 K G I+ + + D + RT + +PNNP G +RE+L + Sbjct: 144 -LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 Query: 262 AKKNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIP 320 +++ + + D Y + D + SI +PG E + S K TG ++GW + P Sbjct: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 Query: 321 KKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY------K 374 ++ K + SQA E L F + Sbjct: 263 DHIM--------KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 Query: 375 ENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ--------------SSWDVFAEILEKT 420 + +I + S+G + + ++ + +++ Sbjct: 315 RCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNK 374 Query: 421 HVVTTPGSGFGPGG-----EGFVRVSAFGHRENILEACRRFKQ 458 +V P S F + ++R + + ++ Sbjct: 375 GLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 >3JTX-A nrPDB Length = 396 Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats. Identities = 88/399 (22%), Positives = 150/399 (37%), Gaps = 56/399 (14%) Query: 89 PDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTF-- 146 + + L IG+ P P+VIT A+ HEL Y G LR A A Sbjct: 28 EGMEAVPLHIGEPKHPTPKVITDALTASLHELE------KYPLTAGLPELRQACANWLKR 81 Query: 147 -YGGLGIGDD-DVFVSDGAKCDISR-LQVMFGS-----NVTIAVQDPSYPAYVDSSVIMG 198 Y GL + D ++ G++ + +Q + I +P Y Y ++++ G Sbjct: 82 RYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGG 141 Query: 199 QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATRE 253 G I + C P F PD ++ RT ++F CSPNNP+G+ + Sbjct: 142 ------------GEIHFANC-PAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLD 188 Query: 254 QLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR-----SIFEIPGAEEVAMETASFSKYAG 308 ++ + K G II D Y+ D N + ++ + + + S SK + Sbjct: 189 GWKEVFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSN 248 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHK 368 G+R G+ +LL K+F + S Q ++A E + Sbjct: 249 VPGLRSGFVAGDAELL--------KNFLLYRTYHGSAMSIPVQRASIAAWDDEQH--VID 298 Query: 369 VIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGS 428 Y+E +I + +DV + Y+W+ P+ + +K + PG Sbjct: 299 NRRLYQEKFERVIPILQQV-FDVKLPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGR 357 Query: 429 GF------GPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 G GEG+VR++ ++A LY+ Sbjct: 358 FLARDTEQGNPGEGYVRIALVADVATCVKAAEDIVSLYR 396 >4IX8-A nrPDB Length = 444 Score = 241 bits (616), Expect = 4e-64, Method: Composition-based stats. Identities = 67/390 (17%), Positives = 143/390 (36%), Gaps = 45/390 (11%) Query: 94 ISLGIGDTTEP----IPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYG- 148 + L IGD T P+++T AM ++ ++GY GA LR ++ + Sbjct: 70 LRLSIGDPTVDGNLKTPDIVTEAMV----DVVRSGKFNGYPPTVGADNLRQVVSTYWRRF 125 Query: 149 ------GLGIGDDDVFVSDG-AKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTG 201 + ++V ++ G ++ + L + I V PS+P Y G Sbjct: 126 CQTKSRQEALKWENVIITSGVSQAIVLALTALCNEGDNILVCAPSFPHYKSVCDSYG--- 182 Query: 202 QFNTDVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLT 256 Y P + DL T +P+NP G+ +R ++ Sbjct: 183 ---------IECRYYYLDPSKSWECDLRAAAGMVDSHTKAFVIINPSNPCGSNFSRAHVS 233 Query: 257 QLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGW 316 +++F +++ ++ D YA + ++ + + +KY G R+GW Sbjct: 234 DIIDFCQQHQIPLISDEIYAEMVLNNGIFTSVADFDTNVPRLILGGTAKYQVCPGWRVGW 293 Query: 317 TVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKEN 376 +++ + + + V + + G ++I Q L E ++ + Sbjct: 294 SILIDPMNVAGDWAVGMER---LTQLIAGVNSICQEAIARTLLKCPTECTEHIVTQLEAG 350 Query: 377 TNIIIDTFT-SLGYDVYGGKNAPYVWVH-----FPN-QSSWDVFAEILEKTHVVTTPGSG 429 + +G + + + +V + F + +S + + ++L++ +V PG Sbjct: 351 AKVYARLLEHDIGISMEAPQASMFVMLKLNLSYFQDLKSDMEFYEKLLDEENVQVLPGEI 410 Query: 430 FGPGGEGFVRVSAFGHRENILEACRRFKQL 459 FG G F+R + + EA R + Sbjct: 411 FGMSG--FLRATVSRPSAVLNEAVDRIIEF 438 >2ZC0-A nrPDB Length = 407 Score = 238 bits (607), Expect = 4e-63, Method: Composition-based stats. Identities = 90/396 (22%), Positives = 154/396 (38%), Gaps = 32/396 (8%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSA-MAKKAHELSTIEGYS-GYGAEQGAKPL 138 + A L+ ++ISL GD PE+I A + + A E+ E S Y G L Sbjct: 24 KKASELQKKGVKLISLAAGDPD---PELIPRAVLGEIAKEVLEKEPKSVMYTPANGIPEL 80 Query: 139 RAAIAKTF--YGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSV 195 R +A Y L + +++ ++ G + L +V+ + ++PSY +++ + Sbjct: 81 REELAAFLKKYDHLEVSPENIVITIGGTGALDLLGRVLIDPGDVVITENPSY---INTLL 137 Query: 196 IMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP--NNPTGAAATRE 253 Q G V + + MR +L G+ + + P NP G + E Sbjct: 138 AFEQLGAKIEGVPV--DNDGMRVDLLEEKIKELKAKGQKVKLIYTIPTGQNPMGVTMSME 195 Query: 254 QLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVR 313 + L+E A K +I+ D+AY + + E + + SK G TG R Sbjct: 196 RRKALLEIASKYDLLIIEDTAYNFMRYEGGDIVPLKALDNEGRVIVAGTLSKVLG-TGFR 254 Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMH--KVIG 371 +GW + ++L K A ISQ AL L E H + Sbjct: 255 IGWIIAEGEIL--------KKVLMQKQPIDFCAPAISQYIALEYLKRGYFEKYHLEGALL 306 Query: 372 FYKENTNIIIDTFTSLGY--DVYGGKNAPYVWVHFPNQSSWDVFA-EILEKTHVVTTPGS 428 YKE +I++ + + +V P + FA E++E+ VV PG Sbjct: 307 GYKEKRDIMLKALENHLPNAEFTKPIAGMFVMFFLPEGADGISFANELMEREGVVVVPGK 366 Query: 429 GF--GPGGEGFVRVSAF-GHRENILEACRRFKQLYK 461 F G+ +R++ +E I ++ +LYK Sbjct: 367 PFYTDESGKNAIRLNFSRPSKEEIPIGIKKLAKLYK 402 >3B1C-A nrPDB Length = 392 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 74/401 (18%), Positives = 141/401 (35%), Gaps = 32/401 (7%) Query: 69 QAGYLFPEIARRRSAHLLKYP----DAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIE 124 + Y F R S H K+ D Q++ I D + + A+ A +L + Sbjct: 5 SSKYNFQTAPNRLSHHTYKWKETETDPQLLPAWIADMDFEVMPEVKQAIHDYAEQL--VY 62 Query: 125 GYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQ 183 GY+ E L ++ Y +D+ +G IS +Q + + Sbjct: 63 GYTYASDELLQAVLDWEKSEHQY---SFDKEDIVFVEGVVPAISIAIQAFTKEGEAVLIN 119 Query: 184 DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPN 243 P YP + S + + N+ ++ G + D+ + C+P+ Sbjct: 120 SPVYPPFARSVRLNNRKLVSNSLKEENGLFQ----IDFEQLENDIVEND-VKLYLLCNPH 174 Query: 244 NPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI--PGAEEVAMETA 301 NP G RE L Q+ +K+ I+V D + + F P ++ A+ + Sbjct: 175 NPGGRVWEREVLEQIGHLCQKHHVILVSDEIHQDLTLFGHEHVSFNTVSPDFKDFALVLS 234 Query: 302 SFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT-- 359 S +K G + + +I L + N +S G +A T Sbjct: 235 SATKTFNIAGTKNSYAIIENPTLCAQFK---------HQQLVNNHHEVSSLGYIATETAY 285 Query: 360 PEGLEAMHKVIGFYKENTNIIIDTFTSL--GYDVYGGKNAPYVWVHFPN--QSSWDVFAE 415 G + + +EN ++ F V + +W+ F + + +F Sbjct: 286 RYGKPWLVALKAVLEENIQFAVEYFAQEAPRLKVMKPQGTYLIWLDFSDYGLTDDALFTL 345 Query: 416 ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRF 456 + ++ V+ GS +G GE R++ + + E C+R Sbjct: 346 LHDQAKVILNRGSDYGSEGELHARLNIAAPKSLVEEICKRI 386 >3AV7-A nrPDB Length = 448 Score = 235 bits (598), Expect = 4e-62, Method: Composition-based stats. Identities = 74/384 (19%), Positives = 136/384 (35%), Gaps = 31/384 (8%) Query: 92 QVISLGIG--DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGG 149 +ISL G + E+I + + + + YG +G PLR + K Sbjct: 77 DIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKAL--QYGTTKGFTPLRETLMKWLGKR 134 Query: 150 LGI-GDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDV 207 GI D+D+ ++ G++ + + +V + V+ P+Y + + + Sbjct: 135 YGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTY-----LAALQAFNFYEPQYI 189 Query: 208 QKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP--NNPTGAAATREQLTQLVEFAKKN 265 Q + E M+ +L + G+ + + P NP G ++ L+E A + Sbjct: 190 QIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEY 249 Query: 266 GSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLY 325 I+V D Y NP + E + +FSK G R+GW V ++ Sbjct: 250 DFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILA-PGFRIGWMVGDPGIIR 308 Query: 326 SDGFPVAKDFNRIICTCFNG--ASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDT 383 +AK + F A G L P ++ FYK + +++ Sbjct: 309 K--MEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIP-------EIRKFYKPRRDAMLEA 359 Query: 384 FTS---LGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGE--GFV 438 G + ++WV P+ E K V PG F + + Sbjct: 360 LEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAFYAHRDVKNTM 419 Query: 439 RVSAF-GHRENILEACRRFKQLYK 461 R++ + I+E +R + K Sbjct: 420 RLNFTYVDEDKIMEGIKRLAETIK 443 >1X0M-A nrPDB Length = 403 Score = 233 bits (595), Expect = 1e-61, Method: Composition-based stats. Identities = 74/384 (19%), Positives = 136/384 (35%), Gaps = 31/384 (8%) Query: 92 QVISLGIG--DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGG 149 +ISL G + E+I + + + + YG +G PLR + K Sbjct: 32 DIISLAGGLPNPKTFPKEIIRDILVEIMEKYADK--ALQYGTTKGFTPLRETLMKWLGKR 89 Query: 150 LGI-GDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDV 207 GI D+D+ ++ G++ + + +V + V+ P+Y + + + Sbjct: 90 YGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTY-----LAALQAFNFYEPQYI 144 Query: 208 QKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP--NNPTGAAATREQLTQLVEFAKKN 265 Q + E M+ +L + G+ + + P NP G ++ L+E A + Sbjct: 145 QIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEY 204 Query: 266 GSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLY 325 I+V D Y NP + E + +FSK G R+GW V ++ Sbjct: 205 DFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILA-PGFRIGWMVGDPGIIR 263 Query: 326 SDGFPVAKDFNRIICTCFNG--ASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDT 383 +AK + F A G L P ++ FYK + +++ Sbjct: 264 K--MEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIP-------EIRKFYKPRRDAMLEA 314 Query: 384 FTS---LGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGE--GFV 438 G + ++WV P+ E K V PG F + + Sbjct: 315 LEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAFYAHRDVKNTM 374 Query: 439 RVSAF-GHRENILEACRRFKQLYK 461 R++ + I+E +R + K Sbjct: 375 RLNFTYVDEDKIMEGIKRLAETIK 398 >4CVQ-A nrPDB Length = 431 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 75/400 (18%), Positives = 141/400 (35%), Gaps = 37/400 (9%) Query: 78 ARRRSAHLLKYPDAQVISLGIGDT---TEPIPEVITSAMAKKAHELSTIEGYSGYGAEQG 134 + A L+ +V+ L IG+ P+ I + + GY +G Sbjct: 46 PVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNL------PTAQGYCDSKG 99 Query: 135 AKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKC-DISRLQVMFGSNVTIAVQDPSYPAYV 191 R AI + + G + +D+++ +G + +Q + S + V P YP + Sbjct: 100 LYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWT 159 Query: 192 DSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPT 246 + + + C + +FPDL + RT I +PNNPT Sbjct: 160 AAVSLSSGKAV------------HYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPT 207 Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKY 306 GA ++E L ++VE A+++ II D Y + DD + + + SK Sbjct: 208 GAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKT 267 Query: 307 AGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 G R GW V+ ++ G+ + + C N + + AL E + Sbjct: 268 YRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQ-SISEFI 326 Query: 367 HKVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWVHFPNQ-----SSWDVFAEILEKT 420 Y E N + + G + A Y++ + + + L + Sbjct: 327 TPGGRLY-EQRNRAWELINDIPGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQE 385 Query: 421 HVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 V+ G+ F R+ ++I + +F + Sbjct: 386 KVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSLSKFARFL 425 >2DOU-A nrPDB Length = 376 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 90/386 (23%), Positives = 162/386 (41%), Gaps = 32/386 (8%) Query: 80 RRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLR 139 +R A +I L IG T P PE A+A+ ++ +T GY + P Sbjct: 17 KRKARER---GVGLIDLSIGSTDLPPPEAPLKALAEALNDPTT----YGYCLKSCTLPFL 69 Query: 140 AAIAKTFYGGLGIGDD---DVFVSDGAKCDISRLQ-VMFGSNVTIAVQDPSYPAYVDSSV 195 A+ + G G+G D + G++ ++ L + + + + +YP+Y ++ Sbjct: 70 EEAARWYEGRYGVGLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSYFGAAR 129 Query: 196 IMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQL 255 + F +++ G + ++ PE + ++ PNNPTGA A Sbjct: 130 V-ASLRTFLIPLREDG-LADLKAVPEGVW-------REAKVLLLNYPNNPTGAVADWGYF 180 Query: 256 TQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 + + A+K+G +++D+ Y + + S +PGA+E +E S SK G RLG Sbjct: 181 EEALGLARKHGLWLIHDNPYVDQVYEGEAPSPLALPGAKERVVELFSLSKSYNLAGFRLG 240 Query: 316 WTVIPKKLLYSDGFPVAKDFNRIICTC-FNGASNISQAGALACLTPEGLEAMHKVIGFYK 374 + + ++ L R+ FN + + + G A TP+ E + Y+ Sbjct: 241 FALGSEEALAR--------LERVKGVIDFNQYAGVLRMGVEALKTPK--EVVRGYARVYR 290 Query: 375 ENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGG 434 E + + + + + Y+W P F L + V PG GFGPGG Sbjct: 291 ERALGMAEALKGV-LSLLPPRATMYLWGRLPEGVDDLEFGLRLVERGVALAPGRGFGPGG 349 Query: 435 EGFVRVSAFGHRENILEACRRFKQLY 460 +GFVR++ E +LEA +R ++ Sbjct: 350 KGFVRIALVRPLEELLEAAKRIREAL 375 >4DQ6-A nrPDB Length = 391 Score = 228 bits (582), Expect = 3e-60, Method: Composition-based stats. Identities = 73/402 (18%), Positives = 142/402 (35%), Gaps = 32/402 (7%) Query: 71 GYLFPEIARRRSAHLLKYPDA-------QVISLGIGDTTEPIPEVITSAMAKKAHELSTI 123 Y F EI R + K+ + ++ + + D I ++ + + I Sbjct: 5 NYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAAPCIIDSLKNRLEQ--EI 62 Query: 124 EGYSGYGAEQGAKPLRAAIAKTFYGGLG--IGDDDVFVSDGAKCDISRL-QVMFGSNVTI 180 GY+ +I Y I + + S G IS L + +N I Sbjct: 63 YGYTTRPDSY-----NESIVNWLYRRHNWKIKSEWLIYSPGVIPAISLLINELTKANDKI 117 Query: 181 AVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFC 240 +Q+P Y + +S V + +QK N Y+ + + + + C Sbjct: 118 MIQEPVYSPF-NSVVKNNNRELIISPLQKLENGNYIM-----DYEDIENKIKDVKLFILC 171 Query: 241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFE--IPGAEEVAM 298 +P+NP G T+++L +L + K+ I+ D ++ + + E+ + Sbjct: 172 NPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMASISKEFEKNTI 231 Query: 299 ETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACL 358 + +K G++ + V+P + Y + CF+ + + Sbjct: 232 TCMAPTKTFNIAGLQSSYVVLPDEKDYKLLDDAFTRIDIKRNNCFSLVATEASYNNGESW 291 Query: 359 TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP--NQSSWDVFAEI 416 LE + I F I + V + +WV F S ++ + + Sbjct: 292 LESFLEYLESNIDFAI---KYINENMPK--LKVRKPEGTYLLWVDFSALGLSDEELESIL 346 Query: 417 LEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 ++K V G+ FG GG G+ R++ R + EA R K Sbjct: 347 VQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKN 388 >2ZJG-A nrPDB Length = 410 Score = 228 bits (580), Expect = 5e-60, Method: Composition-based stats. Identities = 66/407 (16%), Positives = 133/407 (32%), Gaps = 52/407 (12%) Query: 88 YPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIA---K 144 D V++LG G P + ++K A + + Y G L A++ Sbjct: 20 AADPSVVNLGQGFPDISPPSYVKEELSKAAFIDNM----NQYTRGFGHPALVKALSCLYG 75 Query: 145 TFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQF 203 Y ++++ V+ GA + +Q + + + P Y Y + G F Sbjct: 76 KIYQRQIDPNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFYDCYEPMVRMAGAVPVF 135 Query: 204 NTDVQKYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQL 258 K + + + D + +T I +P+NP G TR++L + Sbjct: 136 IPLRSKPTDGMKWT---SSDWTFDPRELESKFSSKTKAIILNTPHNPLGKVYTRQELQVI 192 Query: 259 VEFAKKNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRLGWT 317 + K+ ++ + D Y + + I +PG E + S K TG +LGW+ Sbjct: 193 ADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSAGKTFSVTGWKLGWS 252 Query: 318 VIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC------LTPEGLEAMHKVIG 371 + P L+ K + F + QA + + + Sbjct: 253 IGPAHLI--------KHLQTVQQNSFYTCATPLQAALAEAFWIDIKRMDDPECYFNSLPK 304 Query: 372 FYKENTNIIIDTFTSLGYDVYGGKNAPYVW-------VHFPNQSSWD----VFAEILEK- 419 + + ++ S+G ++ + +S + F + + K Sbjct: 305 ELEVKRDRMVRLLNSVGLKPIVPDGGYFIIADVSSLGADLSDMNSDEPYDYKFVKWMTKH 364 Query: 420 THVVTTPGSGF-----GPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 + P S F P E VR + A +++++ Sbjct: 365 KKLTAIPVSAFCDSKSKPHFEKLVRFCFIKKDSTLDAA----EEIFR 407 >3B46-A nrPDB Length = 447 Score = 226 bits (576), Expect = 2e-59, Method: Composition-based stats. Identities = 82/434 (18%), Positives = 144/434 (33%), Gaps = 44/434 (10%) Query: 56 KTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKY--PDAQVISLGIGDTTEPIPEVITSAM 113 + KV N + A ++ + ++I+LG G + P+ Sbjct: 20 RPKVVANKYFTSNTAKDVWSLTNEAAAKAANNSKNQGRELINLGQGFFSYSPPQFAIKEA 79 Query: 114 AKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKCD-ISRL 170 K I + Y +G L ++ K + + ++V V+ GA +S L Sbjct: 80 QKALD----IPMVNQYSPTRGRPSLINSLIKLYSPIYNTELKAENVTVTTGANEGILSCL 135 Query: 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST 230 + + + V +P + Y+ + + G + + R T + D Sbjct: 136 MGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPPKELDQ--RNTRGEEWTIDFEQ 193 Query: 231 -----VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR 285 +T + +P+NP G TRE+LT L K+ +I+ D Y D+ Sbjct: 194 FEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFTDSFT 253 Query: 286 SIFEI-PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFN 344 I + P ++ + S K TG R+GW + L S AK RI CF Sbjct: 254 RIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYA---AKAHTRI---CFA 307 Query: 345 GASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHF 404 S + +A A + + K+ Y I F LG + +V V F Sbjct: 308 SPSPLQEACANSINDALKIGYFEKMRQEYINKFKIFTSIFDELGLPYTAPEGTYFVLVDF 367 Query: 405 PNQSSWDVFAE----------------ILEKTHVVTTPGSGF-----GPGGEGFVRVSAF 443 + + ++ + VV P + F E +R + Sbjct: 368 SKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAIPPTEFYIKEHEKAAENLLRFAVC 427 Query: 444 GHRENILEACRRFK 457 + A R K Sbjct: 428 KDDAYLENAVERLK 441 >1BW0-A nrPDB Length = 416 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 74/399 (18%), Positives = 137/399 (34%), Gaps = 52/399 (13%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL 150 +I L +GD T + ++A KK E + +GY G+ R A+A + Sbjct: 33 KPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGYFPTVGSPEAREAVATWWRNSF 92 Query: 151 G---------IGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTG 201 + D+ V S G+ + + + + V P +P Y G Sbjct: 93 VHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYG--- 149 Query: 202 QFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLT 256 + + C PEN + DL + +T ++ +P+NP G+ +R+ + Sbjct: 150 ---------IGMHFYNCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVE 200 Query: 257 QLVEFAKKNGSIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAME---TASFSKYAGFTGV 312 +V A++ + D YA + +P + F E + +K G Sbjct: 201 DIVRLAEELRLPLFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGW 260 Query: 313 RLGWTV-IPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIG 371 RLGW + + K ++C G + QA L E + +++ Sbjct: 261 RLGWLLYVDPHGNGPSFLEGLKRVGMLVC----GPCTVVQAALGEALLNTPQEHLDQIVA 316 Query: 372 FYKENTNIIIDTFTS-LGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEK----------T 420 +E+ + + +G + A Y+ + + +I Sbjct: 317 KIEESAMYLYNHIGECIGLAPTMPRGAMYLMSRI----DLEKYRDIKTDVEFFEKLLEEE 372 Query: 421 HVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 +V PG+ F GF R++ E EA R K Sbjct: 373 NVQVLPGTIF--HAPGFTRLTTTRPVEVYREAVERIKAF 409 >1YIY-A nrPDB Length = 429 Score = 214 bits (544), Expect = 8e-56, Method: Composition-based stats. Identities = 69/399 (17%), Positives = 126/399 (31%), Gaps = 48/399 (12%) Query: 94 ISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG 153 ++LG G P+ A A S + Y G L A++K + + Sbjct: 40 LNLGQGFPDYHAPKYAL--NALAAAANSPDPLANQYTRGFGHPRLVQALSKLYSQLVDRT 97 Query: 154 DD---DVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 + +V V+ GA + +Q + + +P + Y G +F Sbjct: 98 INPMTEVLVTVGAYEALYATIQGHVDEGDEVIIIEPFFDCYEPMVKAAGGIPRFIPLKPN 157 Query: 210 YGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAKK 264 + D + + +T +I +P+NP G R +L + KK Sbjct: 158 KTGG----TISSADWVLDNNELEALFNEKTKMIIINTPHNPLGKVMDRAELEVVANLCKK 213 Query: 265 NGSIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKL 323 + V D Y + + I +PG E + S K TG ++GW P+ L Sbjct: 214 WNVLCVSDEVYEHMVFEPFEHIRICTLPGMWERTITIGSAGKTFSLTGWKIGWAYGPEAL 273 Query: 324 LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPE------GLEAMHKVIGFYKENT 377 L K+ + C + Q E + + G Sbjct: 274 L--------KNLQMVHQNCVYTCATPIQEAIAVGFETELKRLKSPECYFNSISGELMAKR 325 Query: 378 NIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWD------------VFAEILEKT-HVVT 424 + + +G + + ++ + + S F + + K+ + Sbjct: 326 DYMASFLAEVGMNPTVPQGGYFMVADWSSLDSKVDLTQETDARKDYRFTKWMTKSVGLQG 385 Query: 425 TPGSGFGPG-----GEGFVRVSAFGHRENILEACRRFKQ 458 P S F GE FVR F EN+ +A ++ Sbjct: 386 IPPSAFYSEPNKHLGEDFVRYCFFKKDENLQKAAEILRK 424 >1VP4-A nrPDB Length = 425 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 75/392 (19%), Positives = 131/392 (33%), Gaps = 37/392 (9%) Query: 88 YPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYS--GYGAEQGAKPLRAAIAKT 145 D IS G G +A+ A E+ E + Y +G L+ I K Sbjct: 40 AADKDAISFGGGVPDPET--FPRKELAEIAKEIIEKEYHYTLQYSTTEGDPVLKQQILKL 97 Query: 146 F---YGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQ 202 YG G+ +D++ + G++ + + +F + + V D PAY+ + Q Sbjct: 98 LERMYGITGLDEDNLIFTVGSQQALDLIGKLFLDDESYCVLDD--PAYLGAINAFRQYLA 155 Query: 203 FNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDII----FFCSPNNPTGAAATREQLTQL 258 V + M + G+ + + +NP G + E+ L Sbjct: 156 NFVVVPL--EDDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNFHNPAGVTTSLEKRKAL 213 Query: 259 VEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTV 318 VE A+K IV D Y + G E + +FSK G+R+G Sbjct: 214 VEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGPERVVLLNTFSKVLA-PGLRIGMVA 272 Query: 319 IPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEG---LEAMHKVIGFYKE 375 K+ + AK + LA E LE + I Y+ Sbjct: 273 GSKEFIRK--IVQAKQSADLCSPAITH--------RLAARYLERYDLLEQLKPTIELYRR 322 Query: 376 NTNIIIDTFTSL-----GYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGF 430 ++++ G + ++W+ P E ++ V PG F Sbjct: 323 KRTVMLNALEEYFSDIPGVKWVKSEGGLFIWLTLPEGFDTWEMFEYAKRKKVFYVPGRVF 382 Query: 431 GPGGE--GFVRVSAF-GHRENILEACRRFKQL 459 E +R+S E I+E +R +++ Sbjct: 383 KVYDEPSPSMRLSFCLPPDEKIVEGIKRLREV 414 >3EZS-A nrPDB Length = 376 Score = 206 bits (524), Expect = 2e-53, Method: Composition-based stats. Identities = 89/407 (21%), Positives = 149/407 (36%), Gaps = 51/407 (12%) Query: 71 GYLFPEIARRRSAHLLKY--PDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSG 128 G F R LLK P + + LGIG+ P+ I A+ H L+ Sbjct: 1 GMTFEPYPFERLRALLKEITPKKRGLDLGIGEPQFETPKFIQDALKNHTHSLNI------ 54 Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIG--DDDVFVSDGAKCDISRLQVMFG---SNVTIAVQ 183 Y + LRAA F I ++++ + G++ + N TIA Sbjct: 55 YPKSAFEESLRAAQRGFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYP 114 Query: 184 DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST--VGRTDIIFFCS 241 +P Y Y ++ + M T EN F P L+ + D++ S Sbjct: 115 NPFYQIYEGAAKFIKAKSLL------------MPLTKENDFTPSLNEKELQEVDLVILNS 162 Query: 242 PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI-----PGAEEV 296 PNNPTG + E+L V+ A K+ I++ D Y+ + P S+ E A + Sbjct: 163 PNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLAGNEAFKN 222 Query: 297 AMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALA 356 + S SK + G+R G+ +LL K F + + A+ I +A A Sbjct: 223 VLVIHSLSKRSSAPGLRSGFIAGDSRLLEK-----YKAFRAYLG--YTSANAIQKASEAA 275 Query: 357 CLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEI 416 L E + Y N + F + Y + YV+ P Q+ + + Sbjct: 276 WLDDRHAEFFRNI---YANNLKLARKIFKNTLIYPY----SFYVY--LPVQNGENFAKTL 326 Query: 417 LEKTHVVTTPGSGFGPG--GEGFVRVSAFGHRENILEACRRFKQLYK 461 + ++T P G G +VR++ + + + Y+ Sbjct: 327 YQNEGIITLPALYLGRNRIGADYVRLALVYDTPLLEKPLE-IIETYR 372 >1WST-A nrPDB Length = 417 Score = 205 bits (522), Expect = 3e-53, Method: Composition-based stats. Identities = 83/425 (19%), Positives = 143/425 (33%), Gaps = 39/425 (9%) Query: 58 KVSRNSNMSKLQAGYLFPEIARRRSAHLLKY-----PDAQVISLGIGDTTEPIPE-VITS 111 K+ + + + F E A A ++ + VISL G P PE Sbjct: 3 KLEKKLSAEPINFDSFFSEKAMLMKASEVRELLKLVETSDVISLAGG---LPAPETFPVE 59 Query: 112 AMAKKAHELSTIEGYS--GYGAEQGAKPLRAAIAKTFYGGLGIGDD--DVFVSDGAKCDI 167 + K A E+ YG +G PLR A+A+ I ++ G++ + Sbjct: 60 TIKKIAVEVLEEHADKALQYGTTKGFTPLRLALARWMEKRYDIPMSKVEIMTVAGSQQAL 119 Query: 168 SRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFP 226 + +V I V+ P+Y A + + K ++ + E Sbjct: 120 DLIGRVFLNPGDPIVVEAPTYLAAIQAFKYYDPEFISIPLDDKGMRVDLLEEKLEEL--- 176 Query: 227 DLSTVGRTDIIF-FCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR 285 R I++ + NP G + ++ +L+E A + +IV D Y+ P Sbjct: 177 -RKQGKRVKIVYTVSTFQNPAGVTMSVDRRKKLLELANEYDFLIVEDGPYSELRYSGEPT 235 Query: 286 SIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNG 345 + + +FSK G R+GW L+ +AK + F Sbjct: 236 PPIKHFDDYGRVIYLGTFSKILA-PGFRIGWVAAHPHLIRK--MEIAKQSIDLCTNTF-- 290 Query: 346 ASNISQAGALACLTPEG---LEAMHKVIGFYKENTNIIIDTFTS---LGYDVYGGKNAPY 399 A+A E E + K+I FYK + +++ G + + + Sbjct: 291 ------GQAIAWKYVENGYLDEHIPKIIEFYKPRRDAMLEALEEYMPEGVEWTKPEGGMF 344 Query: 400 VWVHFPNQSSWDVFAEILEKTHVVTTPGSGF--GPGGEGFVRVSAF-GHRENILEACRRF 456 V V P + E V PG F + +R++ E I E RR Sbjct: 345 VRVTLPEGIDTKLMMERAVAKGVAYVPGEAFFVHRDKKNTMRLNFTYVPEETIREGVRRL 404 Query: 457 KQLYK 461 + K Sbjct: 405 AETIK 409 >3FDB-A nrPDB Length = 377 Score = 205 bits (520), Expect = 5e-53, Method: Composition-based stats. Identities = 73/397 (18%), Positives = 141/397 (35%), Gaps = 35/397 (8%) Query: 71 GYLFPEIARRRSAHLLKYP--DAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSG 128 G FP I R+ + +K+ V+ L + ++ + A+ + G Sbjct: 1 GMQFPSIEDLRARNTMKWTRYGQGVLPLWVAESDFSTCPAVLQAITDAVQREAF-----G 55 Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIG--DDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDP 185 Y + L A A+ + G + +F + + + + V P Sbjct: 56 YQPDGSL--LSQATAEFYADRYGYQARPEWIFPIPDVVRGLYIAIDHFTPAQSKVIVPTP 113 Query: 186 SYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNP 245 +YP + + G F D N+ + E GF I C+P NP Sbjct: 114 AYPPFFHLLSATQREGIF-IDATGGINLHDV----EKGFQAG------ARSILLCNPYNP 162 Query: 246 TGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG-AEEVAMETASFS 304 G E L +L + A + + ++ D +A + D + A V + + S Sbjct: 163 LGMVFAPEWLNELCDLAHRYDARVLVDEIHAPLVFDGQHTVAAGVSDTAASVCITITAPS 222 Query: 305 KYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLE 364 K G++ + A+ + ++ +GAS + A A G + Sbjct: 223 KAWNIAGLKCAQIIFSNP-------SDAEHWQQLSPVIKDGASTLGLIAAEAAYR-YGTD 274 Query: 365 AMHKVIGFYKENTNIIIDTFTSL--GYDVYGGKNAPYVWVHFPNQSSWDVFAE-ILEKTH 421 +++ + + K N + ++ G + + +W+ F + + +E +EK Sbjct: 275 FLNQEVAYLKNNHDFLLHEIPKRIPGAKITPMQATYLMWIDFRDTTIEGSPSEFFIEKAK 334 Query: 422 VVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 V G+ FG G GF R++ RE + EA R + Sbjct: 335 VAMNDGAWFGEDGTGFCRLNFATSREVLEEAIDRMAK 371 >2ZYJ-A nrPDB Length = 397 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 83/386 (21%), Positives = 141/386 (36%), Gaps = 41/386 (10%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYS---GYGAEQGAKPLRAAIAKTFY 147 ++S G P PE+ A +A E Y +G PLRA +A+ Sbjct: 32 PGILSFAGG---LPAPELFPKEEAAEAAARILREKGEVALQYSPTEGYAPLRAFVAEW-- 86 Query: 148 GGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTD 206 +G+ ++V ++ G++ + + +V + ++ PSY MG F Sbjct: 87 --IGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSY---------MGAIQAFRLQ 135 Query: 207 VQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFC-SPNNPTGAAATREQLTQLVEFAKKN 265 ++ + P+ ++ R ++ S NPTG +L++ + Sbjct: 136 GPRFLTVPAGEEGPDLDALEEVLKRERPRFLYLIPSFQNPTGGLTPLPARKRLLQMVMER 195 Query: 266 GSIIVYDSAYAM-YMSDDNPRSIFEI--PGAEEVAMETASFSKYAGFTGVRLGWTVIPKK 322 G ++V D AY Y + S+FE+ + SFSK G+R+ + V + Sbjct: 196 GLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVLS-PGLRVAFAVAHPE 254 Query: 323 LLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIID 382 L AK + N Q L E + +V Y+E ++ Sbjct: 255 ALQK--LVQAKQGADLHTPMLN------QMLVHELLKEGFSERLERVRRVYREKAQAMLH 306 Query: 383 TFTSL---GYDVYGGKNAPYVWVHFP-NQSSWDVFAEILEKTHVVTTPGSGF--GPGGEG 436 K +VW+ P S+ +F LE+ +V PG F GGE Sbjct: 307 ALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLFRRALEE-NVAFVPGGPFFANGGGEN 365 Query: 437 FVRVSAFG-HRENILEACRRFKQLYK 461 +R+S RE I E RR + K Sbjct: 366 TLRLSYATLDREGIAEGVRRLGRALK 391 >2GB3-A nrPDB Length = 409 Score = 203 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 74/391 (18%), Positives = 130/391 (33%), Gaps = 37/391 (9%) Query: 83 AHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAI 142 A + K ++ L IG PEV + + E+ Y G LR A Sbjct: 35 AEMAKKRGVRIHHLNIGQPDLKTPEVFFERIYENKPEVV------YYSHSAGIWELREAF 88 Query: 143 AKTFYGG--LGIGDDDVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQ 199 A + + + ++V V++G + V+ I V +P Y Y + I G Sbjct: 89 ASYYKRRQRVDVKPENVLVTNGGSEAILFSFAVIANPGDEILVLEPFYANYNAFAKIAGV 148 Query: 200 TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLV 259 T + G RT I +P NPTG ++++ LV Sbjct: 149 KLIPVTRRMEEGFAIPQNLESFIN--------ERTKGIVLSNPCNPTGVVYGKDEMRYLV 200 Query: 260 EFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319 E A+++G ++ D Y+ + S I + + S SK G R+G + Sbjct: 201 EIAERHGLFLIVDEVYSEIVFRGEFASALSIES--DKVVVIDSVSKKFSACGARVGCLIT 258 Query: 320 PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNI 379 + L S + + Q G++ L + V Y+E Sbjct: 259 RNEELIS--------HAMKLAQGRLAPPLLEQIGSVGLLNLDDS-FFDFVRETYRERVET 309 Query: 380 IIDTFTSLGY-DVYGGKNAPYVWVHFPNQSSWDVFAEIL-------EKTHVVTTPGSGFG 431 ++ G A Y+ P + + + +L E T V G Sbjct: 310 VLKKLEEHGLKRFTKPSGAFYITAELPVEDAEEFARWMLTDFNMDGETTMVAPLRGFYLT 369 Query: 432 PG-GEGFVRVSAFGHRENILEACRRFKQLYK 461 PG G+ +R++ ++ + A + K Sbjct: 370 PGLGKKEIRIACVLEKDLLSRAIDVLMEGLK 400 >3L8A-A nrPDB Length = 421 Score = 200 bits (507), Expect = 2e-51, Method: Composition-based stats. Identities = 71/422 (16%), Positives = 138/422 (32%), Gaps = 37/422 (8%) Query: 59 VSRNSNMSKLQAG----------YLFPEIARRRSAHLLKYP----DAQVISLGIGDTTEP 104 V R S+M+ + G Y F R + K+ + +++ + + D Sbjct: 15 VPRGSHMASMTGGQQMGRGSMGRYDFTTRPDRLNQFTYKWKTSENNPELLQMWVADMDFL 74 Query: 105 IPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAK 164 I A+ E I GY+ + + + + + +D+ DG Sbjct: 75 PVPEIKEAIINYGRE--HIFGYNYFNDDLYQAVIDW---ERKEHDYAVVKEDILFIDGVV 129 Query: 165 CDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENG 223 IS LQ + + P Y + + + N+ G E Sbjct: 130 PAISIALQAFSEKGDAVLINSPVYYPFARTIRLNDHRLVENSLQIINGRFE----IDFEQ 185 Query: 224 FFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN 283 D+ I CSP+NP G + L ++ E KK+G I+V D + N Sbjct: 186 LEKDIIDNN-VKIYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILVSDEIHQDLALFGN 244 Query: 284 PRSIFEIPGA--EEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICT 341 A ++ + +S +K G + + +I + L R + Sbjct: 245 THHSLNTLDASYKDFTIILSSATKTFNIAGTKNSFAIIQNESLRRKFQ------YRQLAN 298 Query: 342 CFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFT-SLGYDVYGGKNAPYV 400 + + A G + ++ + N ++I V + V Sbjct: 299 NQHEVPTVGMIATQAAFQ-YGKPWLEELKTVIEGNIKLVIKELEAKTKIKVMEPEGTYLV 357 Query: 401 WVHFPNQ--SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 W+ F + + ++ + VV G+ FG G+ F R++ + + EA R Sbjct: 358 WLDFSAYAIAQPQLSEKLQNEAKVVLNDGAHFGKEGKYFARLNVATPKNTVQEALSRIIS 417 Query: 459 LY 460 ++ Sbjct: 418 VF 419 >3OP7-A nrPDB Length = 375 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 69/339 (20%), Positives = 137/339 (40%), Gaps = 34/339 (10%) Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCD-ISRLQVMFGSNVTIAVQDPSY 187 YG +G+ + ++++ + G+ + + ++GA + L + + P+Y Sbjct: 59 YGWIEGSPAFKKSVSQLY---TGVKPEQILQTNGATGANLLVLYSLIEPGDHVISLYPTY 115 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGR-----TDIIFFCSP 242 D +G ++ + ENG+ PDL + + T +I + Sbjct: 116 QQLYDIPKSLGA------------EVDLWQIEEENGWLPDLEKLRQLIRPTTKMICINNA 163 Query: 243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETAS 302 NNPTGA R L +LVE A + G+ I+ D Y + D P SI E+ + + S Sbjct: 164 NNPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSFSELDVP-SIIEV---YDKGIAVNS 219 Query: 303 FSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEG 362 SK G+R+GW ++ +D +D+ I F+ ++Q E Sbjct: 220 LSKTYSLPGIRIGWVAANHQV--TDILRDYRDYTMICAGVFD--DLVAQLAL--AHYQEI 273 Query: 363 LEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHV 422 LE ++ + I+ + Y + +V + + D ++L++ V Sbjct: 274 LERNRHILEENLAILDQWIEEEPLVSYIRPAVVSTSFVKIAV-DMPMEDFCLQLLQEHGV 332 Query: 423 VTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 + PG+ F +G+VR+ +E +++ + Q + Sbjct: 333 LLVPGNRF--ERDGYVRLGFACEQETLIKGLEKLSQFLR 369 >2O0R-A nrPDB Length = 411 Score = 198 bits (502), Expect = 5e-51, Method: Composition-based stats. Identities = 77/382 (20%), Positives = 129/382 (33%), Gaps = 39/382 (10%) Query: 94 ISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG 153 ++LG G E P + A G + Y G+ PLR AIA G+ Sbjct: 28 VNLGQGFPDEDGPPKMLQAAQDAIA-----GGVNQYPPGPGSAPLRRAIAAQRRRHFGVD 82 Query: 154 DD---DVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 D +V V+ GA I+ + + + + +P Y +Y + G V Sbjct: 83 YDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPD 142 Query: 210 YGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSII 269 R + + RT + SP+NPTGA + +L + E A ++ Sbjct: 143 G------RGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVV 196 Query: 270 VYDSAYAMYMSD-DNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDG 328 + D Y + D + G E + +S +K TG ++GW P +L+ G Sbjct: 197 ITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIA--G 254 Query: 329 FPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLG 388 AK + + Q L E + + + + + T +G Sbjct: 255 VRAAKQYLSYVGGA------PFQPAVALALDTEDA-WVAALRNSLRARRDRLAAGLTEIG 307 Query: 389 YDVYGGKNAPYVWVHFPN---QSSWDVFAEILEKTHVVTTPGSGFGPGGEG--------- 436 + V+ ++ S + A + EK V P S F G Sbjct: 308 FAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVW 367 Query: 437 --FVRVSAFGHRENILEACRRF 456 VR + + + EA RR Sbjct: 368 NHLVRFTFCKRDDTLDEAIRRL 389 >3DZZ-A nrPDB Length = 391 Score = 195 bits (495), Expect = 4e-50, Method: Composition-based stats. Identities = 71/400 (17%), Positives = 146/400 (36%), Gaps = 29/400 (7%) Query: 69 QAGYLFPEIARRRSAHLL-KYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYS 127 + Y F + +R+ + + + + I + I I ++M +K + Sbjct: 4 EKQYDFTHVPKRQGNSIKWGVLKEKELPMWIAEMDFKIAPEIMASMEEKLKVAAF----- 58 Query: 128 GYGAEQGAKPLRAAIAKT--FYGGLGIGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQD 184 GY + A+A +D + G IS ++ I VQ+ Sbjct: 59 GYESVP--AEYYKAVADWEEIEHRARPKEDWCVFASGVVPAISAMVRQFTSPGDQILVQE 116 Query: 185 PSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNN 244 P Y + SVI G + + Y N +Y + + ++ FC+P+N Sbjct: 117 PVYNMFY--SVIEGNGRRVISSDLIYENSKYSVNWAD---LEEKLATPSVRMMVFCNPHN 171 Query: 245 PTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYM-SDDNPRSIFEIP-GAEEVAMETAS 302 P G A + E++ ++ E K+ +++ D + + +D++ F + A+ + S Sbjct: 172 PIGYAWSEEEVKRIAELCAKHQVLLISDEIHGDLVLTDEDITPAFTVDWDAKNWVVSLIS 231 Query: 303 FSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEG 362 SK + +IP L + G N+ A EG Sbjct: 232 PSKTFNLAALHAACAIIPNPDLRARAEESF-------FLAGIGEPNLLAIPAAIAAYEEG 284 Query: 363 LEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK--NAPYVWVHFP--NQSSWDVFAEILE 418 + + ++ ++N + +V + WV ++ D + E Sbjct: 285 HDWLRELKQVLRDNFAYAREFLAKEVPEVKVLDSNASYLAWVDISALGMNAEDFCKYLRE 344 Query: 419 KTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 KT ++ + G+G+ G FVR++ +E +++ +R KQ Sbjct: 345 KTGLIISAGNGYRGNGHEFVRINLACPKELVIDGMQRLKQ 384 >3TCM-A nrPDB Length = 500 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 88/394 (22%), Positives = 134/394 (34%), Gaps = 52/394 (13%) Query: 108 VITSAMAKKAHELSTIEGYS--GYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGA 163 ++++ L+ I G + Y QG LR AIA G DD+F++DGA Sbjct: 107 FSADSISRAKQILAMIPGRATGAYSHSQGIHGLRDAIASGIASRDGFPANADDIFLTDGA 166 Query: 164 KCDISRLQVMF--GSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPE 221 + + + I V P YP Y S + G G + + Sbjct: 167 SPGVHLMMQLLIRNEKDGILVPIPQYPLYSASIALHG--GALVPYYLNESTGWGLETSDV 224 Query: 222 NGFFPDLSTVG-RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS 280 D + G + +P NPTG E +V+F K G +++ D Y + Sbjct: 225 KKQLEDARSRGINVRALVVINPGNPTGQVLAEENQYDIVKFCKNEGLVLLADEVYQENIY 284 Query: 281 DDN-----PRSIFEIPGAEEVAMETASF---SK-YAGFTGVRLGWTVIPKKLLYSDGFPV 331 DN + I G E + S+ SK Y G G R G+ + PV Sbjct: 285 VDNKKFHSFKKIVRSLGYGEEDLPLVSYQSVSKGYYGECGKRGGYF-----EITGFSAPV 339 Query: 332 AKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTS----- 386 + +I N SNI+ LA L +A + YK + I+ + Sbjct: 340 REQIYKI--ASVNLCSNIT-GQILASLVMNPPKASDESYASYKAEKDGILASLARRAKAL 396 Query: 387 -------LGYDVYGGKNAPYVW--VHFPNQSSWDV-----------FAEILEKTHVVTTP 426 G + A YV+ + P ++ +LE T +V P Sbjct: 397 EHAFNKLEGITCNEAEGAMYVFPQICLPQKAIEAAKAANKAPDAFYALRLLESTGIVVVP 456 Query: 427 GSGFGP-GGEGFVRVSAFGHRENILEACRRFKQL 459 GSGFG G R + + I RF Sbjct: 457 GSGFGQVPGTWHFRCTILPQEDKIPAVISRFTVF 490 >5Z0Q-C nrPDB Length = 389 Score = 182 bits (462), Expect = 3e-46, Method: Composition-based stats. Identities = 72/404 (17%), Positives = 144/404 (35%), Gaps = 44/404 (10%) Query: 72 YLFPEIARRRSAHLLKYP---DAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSG 128 + F + RR + LK+ D ++ L I DT + I A+ ++ +G G Sbjct: 11 FNFDQRIDRRHSDSLKWKKYADRDILPLWIADTDFRAADCIIDALQQRVQ-----QGVFG 65 Query: 129 YGAEQGAKPLRAAIAKTFYGGLG--IGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDP 185 YG + L + G I + + G I+ ++ ++ + P Sbjct: 66 YGVTS--EALAEVAIERMESRFGWKIQPEWLVFLPGVVTGINIAVRAFTEAHQSTVSATP 123 Query: 186 SYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLS-----TVGRTDIIFFC 240 YP + + + G+ ++ + + DL G ++ C Sbjct: 124 IYPPFFLAPKLAGR-----------QHLSAALRLEQQRWVLDLDSHEDRMSGNEKLLLLC 172 Query: 241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD---NPRSIFEIPGAEEVA 297 +P+NP G R++L + FA+++ ++ D + + + + A + + Sbjct: 173 NPHNPGGTVYRRKELEAQLRFAQRHDLLVCSDEIHCDLVLEPGVQHIPFASLSDDAAQRS 232 Query: 298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC 357 + S SK G+ VIP L + FNR+ ++ A A Sbjct: 233 ITLMSPSKSFNIAGLGASLAVIPNPELRA-------RFNRMRKGMVPDVDVLAYVAASAA 285 Query: 358 LTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYVWVHFPNQSSWDVFAEI 416 EG + + + + N +++ L G + + + W+ D A Sbjct: 286 WR-EGQPWLDAQLDYLRANRDMLAQHVNRLPGLSMVTPEASFLGWIDASGLGVAD-PALF 343 Query: 417 LEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 460 EK + + G FG + FVR + R+ + EA +R + Sbjct: 344 FEKHGLGFSSGRDFG--NDRFVRFNFGCPRQLLEEALQRMTRAL 385 >5TON-A nrPDB Length = 414 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 80/384 (20%), Positives = 131/384 (34%), Gaps = 46/384 (11%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYG 130 P + + A + PD + ++LG+G D +P + + ++ S++ Y Sbjct: 16 PVLVFKLIADFREDPDPRKVNLGVGAYRTDDCQPWVLPVVRKVEQRIANNSSLN--HEYL 73 Query: 131 AEQGAKPLRAAIAKTFYGGLGIGDDDVFV---------SDGAKCDISRLQVMFGSNVTIA 181 G R ++ L +GDD + S G + R+ F + Sbjct: 74 PILGLAEFRTCASR-----LALGDDSPALQEKRVGGVQSLGGTGAL-RIGAEFLARWYNG 127 Query: 182 VQDPSYPAYVDSSVIMGQTGQFNT------DVQKYGNIEYMRCTPENGFFPDLSTVGRTD 235 + P YV S G F T +Y + E R GF DL Sbjct: 128 TNNKDTPVYVSSPTWENLNGVFTTAGFKDIRSYRYWDTE-KRGLDLQGFLSDLENAPEFS 186 Query: 236 IIFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE 294 I +NPTG T EQ Q+ K+ +DSAY + S + + + I Sbjct: 187 IFVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGNLEKDAWAIRYFV 246 Query: 295 EVAMET---ASFSKYAGFTGVRLG-WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 E SFSK G R+G TV+ K+ V +I+ ++ + Sbjct: 247 SEGFELFCAQSFSKNFGLYNERVGNLTVVAKE--PDSILRVLSQMQKIVRVTWSNPP--A 302 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 Q + T E H+ G K + I+ + L + K P W H +Q Sbjct: 303 QGARIVARTLSDPELFHEWTGNVKTMADRILSMRSELRARLEALK-TPGTWNHITDQIGM 361 Query: 411 DVF--------AEILEKTHVVTTP 426 F ++ + H+ P Sbjct: 362 FSFTGLNPKQVEYLINQKHIYLLP 385 >3CQ5-A nrPDB Length = 369 Score = 174 bits (440), Expect = 9e-44, Method: Composition-based stats. Identities = 80/409 (19%), Positives = 147/409 (35%), Gaps = 58/409 (14%) Query: 63 SNMSKLQAGYLFPEIARRRSAHLLKYPDAQV-ISLGIGDTTEPIPEVITSAMAKKAHELS 121 S+M+K+ L P R H P V I L + P E + + + +++ Sbjct: 2 SHMTKITLSDL-PLREELRGEHAYGAPQLNVDIRLNTNENPYPPSEALVADLVATVDKIA 60 Query: 122 TIEGYSGYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNV 178 T + Y E+ A LR +A G+ + D+++ ++G+ + LQ G Sbjct: 61 T--ELNRY-PERDAVELRDELAAYITKQTGVAVTRDNLWAANGSNEILQQLLQAFGGPGR 117 Query: 179 TIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLS------TVG 232 T PSY + + K + E++ + F D+ Sbjct: 118 TALGFQPSYSMH--------------PILAKGTHTEFIAVSRGADFRIDMDVALEEIRAK 163 Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG 292 + DI+F +PNNPTG + + + +++ A I++ D AYA + + ++ E Sbjct: 164 QPDIVFVTTPNNPTGDVTSLDDVERIINVA---PGIVIVDEAYAEFSPSPSATTLLEKYP 220 Query: 293 AEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQA 352 + + + + SK F G RLG+ V + + ++ S +SQA Sbjct: 221 TK--LVVSRTMSKAFDFAGGRLGYFVANPAFIDAV----------MLVRLPYHLSALSQA 268 Query: 353 GALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ-SSWD 411 A+ L + + LGY V ++ + F +Q ++W Sbjct: 269 AAIVALR--HSADTLGTVEKLSVERVRVAARLEELGYAVVPSESNFVFFGDFSDQHAAWQ 326 Query: 412 VFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN---ILEACRRFK 457 F V+ G G +R + EN + A K Sbjct: 327 AFL----DRGVLIR-----DVGIAGHLRTTIGVPEENDAFLDAAAEIIK 366 >3II0-A nrPDB Length = 422 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 82/416 (19%), Positives = 138/416 (33%), Gaps = 48/416 (11%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYG 130 P + + +A + PD + ++LG+G D P + + +K +++ Y Sbjct: 3 PVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLN--HEYL 60 Query: 131 AEQGAKPLRAAIAKTFYGGLGIGDDDVFV---------SDGAKCDISRLQVMFGSNVTIA 181 G R+ ++ L +GDD + S G + R+ F + Sbjct: 61 PILGLAEFRSCASR-----LALGDDSPALKEKRVGGVQSLGGTGAL-RIGADFLARWYNG 114 Query: 182 VQDPSYPAYVDSSVIMGQTGQF------NTDVQKYGNIEYMRCTPENGFFPDLSTVGRTD 235 + + P YV S F + +Y + E R GF DL Sbjct: 115 TNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAE-KRGLDLQGFLNDLENAPEFS 173 Query: 236 IIFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE 294 I+ +NPTG T EQ Q+ K +DSAY + S + R + I Sbjct: 174 IVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFV 233 Query: 295 EVAMET---ASFSKYAGFTGVRLG-WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 E SFSK G R+G TV+ K+ V +I+ ++ + Sbjct: 234 SEGFEFFCAQSFSKNFGLYNERVGNLTVVGKE--PESILQVLSQMEKIVRITWSNPP--A 289 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 Q + T E + G K + I+ + L + K P W H +Q Sbjct: 290 QGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALK-TPGTWNHITDQIGM 348 Query: 411 DVF--------AEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458 F ++ + H+ P G + I EA + + Sbjct: 349 FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATS--IHEAVTKIAE 402 >1D2F-A nrPDB Length = 390 Score = 166 bits (421), Expect = 1e-41, Method: Composition-based stats. Identities = 62/378 (16%), Positives = 125/378 (33%), Gaps = 25/378 (6%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL 150 A ++ I D I A+ ++ G GY + AAIA F Sbjct: 28 ADLLPFTISDMDFATAPCIIEALNQRLMH-----GVFGYSRWK-NDEFLAAIAHWFSTQH 81 Query: 151 GIGDDDVFVSDGAKCDIS---RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDV 207 D V G ++ + + + P+Y A+ + + V Sbjct: 82 YTAIDSQTVVYGPSVIYMVSELIRQWSETGEGVVIHTPAYDAFYKAIE---GNQRTVMPV 138 Query: 208 QKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGS 267 + C + G + I+ CSP NPTG T ++L + + +++G Sbjct: 139 ALEKQADGWFC--DMGKLEAVLAKPECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGV 196 Query: 268 IIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD 327 ++ D + + + P + + A+ T+ SK + + +I Sbjct: 197 RVISDEIHMDMVWGEQPHIPWSNVARGDWALLTSG-SKSFNIPALTGAYGIIENSSSRDA 255 Query: 328 GFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL 387 K + S ++ +A +G + + + K+N I D + Sbjct: 256 YLSALKG-----RDGLSSPSVLALTAHIAAYQ-QGAPWLDALRIYLKDNLTYIADKMNAA 309 Query: 388 --GYDVYGGKNAPYVWVHFPNQSSWDVFAE--ILEKTHVVTTPGSGFGPGGEGFVRVSAF 443 + ++ W+ + D + ++E+ V PG +G G GFVR++A Sbjct: 310 FPELNWQIPQSTYLAWLDLRPLNIDDNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAG 369 Query: 444 GHRENILEACRRFKQLYK 461 R + + + Sbjct: 370 CPRSKLEKGVAGLINAIR 387 >1C7O-A nrPDB Length = 399 Score = 161 bits (407), Expect = 7e-40, Method: Composition-based stats. Identities = 68/417 (16%), Positives = 136/417 (32%), Gaps = 38/417 (9%) Query: 54 EYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAM 113 ++ TK+SR N+ L+ ++ + +V+ L + D P + + Sbjct: 4 DFTTKISR-KNLGSLKWDLMYSQNPE---------VGNEVVPLSVADMEFKNPPELIEGL 53 Query: 114 AKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGG--LGIGDDDVFVSDGAKCDIS-RL 170 K E T+ GY+G + + + K I D + + G + + Sbjct: 54 KKYLDE--TVLGYTGPT-----EEYKKTVKKWMKDRHQWDIQTDWIINTAGVVPAVFNAV 106 Query: 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST 230 + + + P Y Y I Q + + Y T + LS Sbjct: 107 REFTKPGDGVIIITPVY--YPFFMAIKNQERKIIECELLEKDGYY---TIDFQKLEKLSK 161 Query: 231 VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 290 + FCSP+NP G +++L ++ + K+ ++ D + + ++F+ Sbjct: 162 DKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLIMPGYEHTVFQS 221 Query: 291 PG--AEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASN 348 + + + SK G+ + +I + + F + Sbjct: 222 IDEQLADKTITFTAPSKTFNIAGMGMSNIIIKNPDI-------RERFTKSRDATSGMPFT 274 Query: 349 ISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGG--KNAPYVWVHFPN 406 A E + + I +N I+ D F ++ + W+ F Sbjct: 275 TLGYKACEICYKECGKWLDGCIKVIDKNQRIVKDFFEVNHPEIKAPLIEGTYLQWIDFRA 334 Query: 407 QSSWDVFAE--ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 E ++ K + G FG GG GF R++ I E+ R + K Sbjct: 335 LKMDHKAMEEFMIHKAQIFFDEGYIFGDGGIGFERINLAAPSSVIQESLERLNKALK 391 >3FTB-A nrPDB Length = 361 Score = 159 bits (401), Expect = 3e-39, Method: Composition-based stats. Identities = 59/362 (16%), Positives = 130/362 (35%), Gaps = 38/362 (10%) Query: 88 YPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFY 147 + +++ IP+ + + + L + + K+ Sbjct: 23 FKGRELLDYSSNINPLGIPKSFLNNIDEGIKNLGVYPDVNY-----------RRLNKSIE 71 Query: 148 GGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDV 207 L + D + + +GA I +F I + PSY Y ++ G + F+ Sbjct: 72 NYLKLKDIGIVLGNGASEIIELSISLF---EKILIIVPSYAEYEINAKKHGVSVVFS--- 125 Query: 208 QKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGS 267 Y+ + +S + D + +PNNP G +E+ +++ A++ Sbjct: 126 -------YLDENMCIDYEDIISKIDDVDSVIIGNPNNPNGGLINKEKFIHVLKLAEEKKK 178 Query: 268 IIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD 327 I+ D A+ + D + + EI + + + +K+ G+R G+ + K + + Sbjct: 179 TIIIDEAFIEFTGDPSSSFVGEIKNYSCLFI-IRAMTKFFAMPGIRFGYGITNNKEIAAK 237 Query: 328 GFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL 387 +N CF ++ A+ CL + + + + K+ I+ + Sbjct: 238 IKAKQNPWN---INCF------AEMAAINCLKDTN--YIEESLLWIKKERKRFIEELNKI 286 Query: 388 GY-DVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHR 446 G+ +A +V N S ++ +L K +V F + FVR + + Sbjct: 287 GFIKRVFSPHANFVLCRLENISGEKLYDSLL-KEDIVIRRCCNFIGLDDSFVRFAIKDEK 345 Query: 447 EN 448 +N Sbjct: 346 KN 347 >1IAY-A nrPDB Length = 428 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 71/410 (17%), Positives = 124/410 (30%), Gaps = 50/410 (12%) Query: 84 HLLKYPDAQVISLGIGDTTE-----------PIPEVITSAMAKKAHELSTIEGYSGYGAE 132 H LK P+ VI +G+ + I S K ++ + Y Sbjct: 30 HPLKNPNG-VIQMGLAENQLCLDLIEDWIKRNPKGSICSEGIKSFKAIANFQDYH----- 83 Query: 133 QGAKPLRAAIAKT----FYGGLGIGDDDVFVSDGAKCDISRLQVMF-GSNVTIAVQDPSY 187 G R AIAK G + + V ++ GA + V P Y Sbjct: 84 -GLPEFRKAIAKFMEKTRGGRVRFDPERVVMAGGATGANETIIFCLADPGDAFLVPSPYY 142 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTG 247 PA+ + N + + + + + + +P+NP G Sbjct: 143 PAFNRDLRWRTGVQLIPIHCESSNNFKITSKAVKEAYENAQKSNIKVKGLILTNPSNPLG 202 Query: 248 AAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSD-DNPRSIFEIPG-------AEEVAME 299 ++ L ++ F ++ +V D YA + D SI EI +++ Sbjct: 203 TTLDKDTLKSVLSFTNQHNIHLVCDEIYAATVFDTPQFVSIAEILDEQEMTYCNKDLVHI 262 Query: 300 TASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 S SK G G R+G ++YS V ++ F S +Q A L+ Sbjct: 263 VYSLSKDMGLPGFRVG-------IIYSFNDDVVNCARKMS--SFGLVSTQTQYFLAAMLS 313 Query: 360 PEGL--EAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEIL 417 E + + + + +G + W+ F + Sbjct: 314 DEKFVDNFLRESAMRLGKRHKHFTNGLEVVGIKCLKNNAGLFCWMDLRPLLRESTFDSEM 373 Query: 418 EKTHVVTT-------PGSGFGPGGEGFVRVSAFG-HRENILEACRRFKQL 459 V+ PGS F G+ RV + A R ++ Sbjct: 374 SLWRVIINDVKLNVSPGSSFECQEPGWFRVCFANMDDGTVDIALARIRRF 423 >4M2J-A nrPDB Length = 406 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 68/348 (19%), Positives = 117/348 (33%), Gaps = 44/348 (12%) Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYP 188 QG + +R AIA + GG D V V+ G+ I+ L + + VQ+ Y Sbjct: 81 SVSQGGEGVRRAIADRYAGG---DADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYH 137 Query: 189 AYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGA 248 + G + V + P+ T + P+NPTG Sbjct: 138 SLGHYPRAAG----CDVAVLPGRAVRDGEIDPDVLAGL---VTPGTAAVIVNFPHNPTGV 190 Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE-EVAMETASFSKYA 307 + + L L E G+++V+D+A A + + PGA+ + + SK Sbjct: 191 TLSPQGLRALKERTAATGAVLVWDAATAEIA---HRWEVLADPGADGGDTVSYGTLSKTF 247 Query: 308 GFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS------QAGALACLTPE 361 G G+R+GW V PK+LL + FP+ + + + GA A Sbjct: 248 GLPGLRVGWAVAPKELLTAT-FPLRDRTTLFLSPLVELVAERAVRHADELIGARAAEARH 306 Query: 362 GLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPN--------QSSWDVF 413 L + + ++E + F Q Sbjct: 307 NLAHLTGWMAAHEE------------LVRWTPPEGGVCALPVFRELERAAAGPQEVERFC 354 Query: 414 AEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 E+LE+ + PG+ FG R+ G +E+ + + Sbjct: 355 LELLERHRTLLVPGTAFG--APHGARLGFGGPQEDFRAGLDGLSRFLR 400 >4RAE-A nrPDB Length = 394 Score = 154 bits (389), Expect = 7e-38, Method: Composition-based stats. Identities = 73/402 (18%), Positives = 146/402 (36%), Gaps = 41/402 (10%) Query: 59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQV-ISLGIGDTTEPIPEVITSAMAKKA 117 ++R+ + L P A R P V + L + P + + + Sbjct: 2 MTRSGHPVTL---DDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSV 58 Query: 118 HELSTIEGYSGYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGAKCDISRLQVMFG 175 E + Y ++ A LRA +A G+ +G ++++ ++G+ + +L FG Sbjct: 59 REAAID--LHRY-PDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFG 115 Query: 176 SNVTIAVQD-PSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRT 234 A+ PSY + S + +G + + Sbjct: 116 GPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAA--------VVDRKP 167 Query: 235 DIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE 294 D++F SPNNP+G + + L +L++ A I + D AY + S + S+ E ++ Sbjct: 168 DVVFIASPNNPSGQSVSLPDLCKLLDVA---PGIAIVDEAYGEFSSQPSAVSLVEEYPSK 224 Query: 295 EVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGA 354 + T + SK F G RLG+ + ++ + ++ S+++QA A Sbjct: 225 --LVVTRTMSKAFAFAGGRLGYLIATPAVIDA----------MLLVRLPYHLSSVTQAAA 272 Query: 355 LACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ-SSWDVF 413 A L + + + + +G+ V ++ F + ++W + Sbjct: 273 RAALR--HSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRY 330 Query: 414 AEILEKTHVVTTPG-----SGFGPGGEGFVRVSAFGHRENIL 450 E V PG +G + F+R SA + + Sbjct: 331 LEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVP 372 >2CST-A nrPDB Length = 411 Score = 151 bits (382), Expect = 4e-37, Method: Composition-based stats. Identities = 62/366 (16%), Positives = 118/366 (32%), Gaps = 38/366 (10%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYG 130 P + +A + D++ ++LG+G D +P + + + ++ Y Sbjct: 13 PVAVFKLTADFREDGDSRKVNLGVGAYRTDEGQPWVLPVVRKVEQLIAGDGSLN--HEYL 70 Query: 131 AEQGAKPLRAAIAKTFYGGLGIGDDDVFVS---DGAKCDI-----SRLQVMFGSNVTIAV 182 G RA ++ + +GDD ++ G+ + R+ F Sbjct: 71 PILGLPEFRANASR-----IALGDDSPAIAQKRVGSVQGLGGTGALRIGAEFLRRWYNGN 125 Query: 183 QDPSYPAYVDSSVIMGQTGQF------NTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI 236 + + P YV S F + +Y + R G D+ I Sbjct: 126 NNTATPVYVSSPTWENHNSVFMDAGFKDIRTYRYWDA-AKRGLDLQGLLDDMEKAPEFSI 184 Query: 237 IFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE 295 +NPTG T ++ Q+ K+ +DSAY + S + + + Sbjct: 185 FILHACAHNPTGTDPTPDEWKQIAAVMKRRCLFPFFDSAYQGFASGSLDKDAWAVRYFVS 244 Query: 296 VAMET---ASFSKYAGFTGVRLG--WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 E SFSK G R+G V + + V +I+ T ++ S Sbjct: 245 EGFELFCAQSFSKNFGLYNERVGNLSVVGKDE---DNVQRVLSQMEKIVRTTWSNPP--S 299 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 Q + T + + K + ++ + L + P W H +Q Sbjct: 300 QGARIVATTLTSPQLFAEWKDNVKTMADRVLLMRSELRSRLESL-GTPGTWNHITDQIGM 358 Query: 411 DVFAEI 416 F + Sbjct: 359 FSFTGL 364 >3IHJ-A nrPDB Length = 498 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 80/441 (18%), Positives = 141/441 (31%), Gaps = 62/441 (14%) Query: 79 RRRSAHLLKYPDAQVISLGIGD---------------------TTEPIPEVITSAMAKKA 117 +K P +VI IGD K+A Sbjct: 51 ELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRA 110 Query: 118 HELSTIEGYSG---YGAEQGAKPLRAAIAKTFY---GGLGIGDDDVFVSDGAKCDISRLQ 171 + G + Y A QG +R +A GG+ D+++++ GA IS + Sbjct: 111 RRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTIL 170 Query: 172 VMFGSN-----VTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFP 226 + S + + P YP Y S+VI N + Sbjct: 171 KILVSGGGKSRTGVMIPIPQYPLY--SAVISELDAIQVNYYLDEENCWALNVNELRRAVQ 228 Query: 227 DLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRS 286 + ++ +P NPTG +R+ + ++ FA + ++ D Y + + R Sbjct: 229 EAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRF 288 Query: 287 I------FEIPGAEEVAMETASF---SKYA-GFTGVRLGWTVIPKKLLYSDGFPVAKDFN 336 +E+ +E ASF SK G G R G+ + G V Sbjct: 289 HSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSV 348 Query: 337 RIICTCFNGAS---NISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVY 392 R+ A+ ++ A + V+G + + D F + G Sbjct: 349 RLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCN 408 Query: 393 GGKNAPYVW--VHFPNQS-----------SWDVFAEILEKTHVVTTPGSGFG-PGGEGFV 438 + A Y + + P ++ ++LE+T + PGSGFG G Sbjct: 409 PLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHF 468 Query: 439 RVSAFGHRENILEACRRFKQL 459 R++ E + ++ K Sbjct: 469 RMTILPPVEKLKTVLQKVKDF 489 >3NRA-A nrPDB Length = 407 Score = 149 bits (376), Expect = 2e-36, Method: Composition-based stats. Identities = 65/382 (17%), Positives = 127/382 (33%), Gaps = 22/382 (5%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 R A + P + GD P + + ++ Y+ Y + G + L A Sbjct: 33 RGAPIEGRP----VDFSHGDVDAHEPTPGAFDLFSAGVQSGGVQAYTEYRGDLGIRDLLA 88 Query: 141 AIAKTFYGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQ 199 F G D + ++ G + + + +A+ P Y + + ++ Sbjct: 89 PRLAAFTGAPVDARDGLIITPGTQGALFLAVAATVARGDKVAIVQPDY--FANRKLVEFF 146 Query: 200 TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLV 259 G+ Y + + R + + G + F +PNNP G + E++ Q+ Sbjct: 147 EGEMVPVQLDYVSADETRAGLDLTGLEEAFKAG-ARVFLFSNPNNPAGVVYSAEEIGQIA 205 Query: 260 EFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA--EEVAMETASFSKYAGFTGVRLGWT 317 A + G+ ++ D Y+ + A E + SK +G RLG Sbjct: 206 ALAARYGATVIADQLYSRLRYAGASYTHLRAEAAVDAENVVTIMGPSKTESLSGYRLGVA 265 Query: 318 VIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENT 377 + ++ ++ A+ SQ L E M I ++ Sbjct: 266 FGSRAIIAR--------MEKLQAIVSLRAAGYSQ-AVLRGWFDEAPGWMEDRIARHQAIR 316 Query: 378 NIIIDTFTS-LGYDVYGGKNAPYVWVHFPNQ--SSWDVFAEILEKTHVVTTPGSGFGPGG 434 + ++ G + Y++ P + + + + VV TPG+ F P Sbjct: 317 DELLHVLRGCEGVFARTPQAGSYLFPRLPKLAVAPAEFVKILRLQAGVVVTPGTEFSPHT 376 Query: 435 EGFVRVSAFGHRENILEACRRF 456 VR++ E + A RR Sbjct: 377 ADSVRLNFSQDHEAAVAAARRI 398 >1M4N-A nrPDB Length = 435 Score = 148 bits (372), Expect = 6e-36, Method: Composition-based stats. Identities = 58/374 (15%), Positives = 118/374 (31%), Gaps = 34/374 (9%) Query: 111 SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAI----AKTFYGGLGIGDDDVFVSDGAKCD 166 A A K + S + + G + A+ A+ + + + ++ GA Sbjct: 64 EAAAFKKNGESIFAELALFQDYHGLPAFKKAMVDFMAEIRGNKVTFDPNHLVLTAGATSA 123 Query: 167 ISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFF 225 + + + + P YP + + E + Sbjct: 124 NETFIFCLADPGEAVLIPTPYYPGFDRDLKWRTGVEIVPIHCTSSNGFQITETALEEAYQ 183 Query: 226 PDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMY-MSDDNP 284 R + +P+NP G TR +L L+ F + G ++ D Y+ S + Sbjct: 184 EAEKRNLRVKGVLVTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSF 243 Query: 285 RSIFEIPGAEE---------VAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 335 S+ E+ S SK G G R+G ++ + ++ Sbjct: 244 ISVMEVLKDRNCDENSEVWQRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAATKMS--- 300 Query: 336 NRIICTCFNGASNISQAGALACLTPEGL--EAMHKVIGFYKENTNIIIDTFTSLGYDVYG 393 F S+ +Q A L+ + L + + K+ ++ G Sbjct: 301 ------SFGLVSSQTQHLLSAMLSDKKLTKNYIAENHKRLKQRQKKLVSGLQKSGISCLN 354 Query: 394 GKNAPYVWVHFPN-------QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAF-GH 445 G + WV + ++ +++ +I+ + H+ +PGS G+ RV Sbjct: 355 GNAGLFCWVDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWFRVCFANLP 414 Query: 446 RENILEACRRFKQL 459 + A +R K Sbjct: 415 ERTLDLAMQRLKAF 428 >4R2N-A nrPDB Length = 367 Score = 148 bits (372), Expect = 7e-36, Method: Composition-based stats. Identities = 81/377 (21%), Positives = 129/377 (34%), Gaps = 47/377 (12%) Query: 89 PDAQV---ISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKT 145 P V I L +T P A +A + + Y G L+AA+A+ Sbjct: 18 PGKTVPGAIKLASNETVFG-PLPSVRAAIDRATDTV-----NRYPDN-GCVQLKAALARH 70 Query: 146 FYGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFN 204 G + V V G+ +L QV + S+ Y + G Sbjct: 71 L--GPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQV 128 Query: 205 TDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKK 264 ++ M T RT +IF C+PNNPT + L + VE Sbjct: 129 PLTDHTFDLYAMLAT----------VTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPA 178 Query: 265 NGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324 + +I D AY Y+ D + A + +FSK G G+R+G+ + ++ Sbjct: 179 H-ILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVI 237 Query: 325 YSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTF 384 + S+I QA A+A L E + + E + + Sbjct: 238 TALD----------KVYVPFTVSSIGQAAAIASLDAAD-ELLARTDTVVAERARVSAE-L 285 Query: 385 TSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFG 444 + G+ + A +VW P S F E +V P G VRV+ Sbjct: 286 RAAGFTL-PPSQANFVW--LPLGSRTQDFVEQAADARIVVRP------YGTDGVRVTVAA 336 Query: 445 HRENILEACRRFKQLYK 461 EN +A RF + ++ Sbjct: 337 PEEN--DAFLRFARRWR 351 >1UU1-A nrPDB Length = 335 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 70/368 (19%), Positives = 126/368 (34%), Gaps = 52/368 (14%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 + A+ + L + + P PE + + ++ + + Y + L Sbjct: 9 KRAYPYETEKRDKTYLALNENPFPFPEDLVDEVFRRLNSDALRIYYDSP-----DEELIE 63 Query: 141 AIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQT 200 I + ++V V +GA I + +MF +V P+Y Y + +G Sbjct: 64 KILSYLDTDF-LSKNNVSVGNGADEIIYVMMLMFDRSVF---FPPTYSCYRIFAKAVGAK 119 Query: 201 GQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVE 260 + E VG D++F +PNNPTG RE++ +++ Sbjct: 120 FLEVPLTKDLRIPEV--------------NVGEGDVVFIPNPNNPTGHVFEREEIERIL- 164 Query: 261 FAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIP 320 K G+ + D AY + + S + E +FSK R+G+ V Sbjct: 165 ---KTGAFVALDEAYYEFHGE----SYVDFLKKYENLAVIRTFSKAFSLAAQRVGYVVAS 217 Query: 321 KKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNII 380 +K + + V FN S +SQ A L E + F E + Sbjct: 218 EKFIDAYN-RVRLPFN---------VSYVSQMFAKVALD--HREIFEERTKFIVEERERM 265 Query: 381 IDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRV 440 +GY + + +V+V + + + K +V F G VR+ Sbjct: 266 KSALREMGYRITDSRGN-FVFVFMEKEEKERLLEHLRTK-NVAV---RSFREG----VRI 316 Query: 441 SAFGHREN 448 + EN Sbjct: 317 TIGKREEN 324 >3FKD-A nrPDB Length = 350 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 59/374 (15%), Positives = 128/374 (34%), Gaps = 50/374 (13%) Query: 92 QVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLG 151 ++++ T + + K E + Y E A LR +AK Sbjct: 16 EIVNFS----TTVWTDGDKDHLEKHLVEN--LNCIRHY-PEPDAGTLRQMLAKRN----S 64 Query: 152 IGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYG 211 + ++ + V++G ++ F + PS+ Y D+ + F + G Sbjct: 65 VDNNAILVTNGPTAAFYQIAQAF-RGSRSLIAIPSFAEYEDACRMYEHEVCFYPSNEDIG 123 Query: 212 NIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVY 271 ++ D + C+PNNP G R ++ +L+ + V Sbjct: 124 EADFSNM----------------DFCWLCNPNNPDGRLLQRTEILRLLN--DHPDTTFVL 165 Query: 272 DSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPV 331 D +Y + +++ R +I G + + M SFS G G+R+G+ V K + Sbjct: 166 DQSYVSFTTEEVIRPA-DIKGRKNLVM-VYSFSHAYGIPGLRIGYIVANKDFMKR----- 218 Query: 332 AKDFNRIICTCFNGASNISQAGALACL--TPEGLEAMHKVIGFYKENTNIIIDTFTSLGY 389 F+ ++ A + + + + + I L Sbjct: 219 --------VAAFSTPWAVNALAIEAAKFILIHPAQFTLPIRKWQRNTVDFIT-ALNRLDG 269 Query: 390 DVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN- 448 + + ++ ++ +LE+ +++ S F E +VR++ +N Sbjct: 270 VEVHPSGTTFFLLRLKKGTAAELKKYMLEEYNMLIRDASNFRGLDESYVRITTQRPAQNQ 329 Query: 449 -ILEACRRFKQLYK 461 ++A F + Y+ Sbjct: 330 LFIKALETFLEKYE 343 >4GDY-A nrPDB Length = 439 Score = 138 bits (347), Expect = 6e-33, Method: Composition-based stats. Identities = 69/414 (16%), Positives = 134/414 (32%), Gaps = 43/414 (10%) Query: 80 RRSAHLLKYPDAQVISLGIGDT-----TEPIPEVITSAMAKKAHELSTIEGYSGYGAEQG 134 R +L +ISL G + ++ Y G Sbjct: 20 RTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAG 79 Query: 135 AKPLRAAIAKTFYGGLGIGDD----------DVFVSDGAKCDI-SRLQVMFGSNVTIAVQ 183 L + K L D+ V+ G++ + +++ + + Sbjct: 80 IPELLS-WLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLD 138 Query: 184 DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGR---TDIIF-F 239 +P+Y + S +G + + +R + + P+ + + ++ Sbjct: 139 EPAYSGTLQSLHPLGCNIINVASDESGIVPDSLR-DILSRWKPEDAKNPQKNTPKFLYTV 197 Query: 240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAME 299 + NNPTG + T E+ ++ E A+K +I+ D Y + F + + Sbjct: 198 PNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIR 257 Query: 300 TASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 SFSK +G+R+G+ PK L+ + S +Q L Sbjct: 258 ADSFSKIIS-SGLRIGFLTGPKPLIERVILHIQ--------VSTLHPSTFNQLMISQLLH 308 Query: 360 PEGLEAM----HKVIGFYKENTNIIIDTFTS--LGY-DVYGGKNAPYVWVHFPNQSS-WD 411 G E +VI FY + I+ G + + ++W+ + + Sbjct: 309 EWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKE 368 Query: 412 VFAEILEKTHVVTTPGSGF---GPGGEGFVRVSA-FGHRENILEACRRFKQLYK 461 + E K V+ PG+ F ++R S E + A + QL K Sbjct: 369 LIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIK 422 >1LC8-A nrPDB Length = 364 Score = 132 bits (333), Expect = 2e-31, Method: Composition-based stats. Identities = 58/383 (15%), Positives = 114/383 (29%), Gaps = 49/383 (12%) Query: 80 RRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLR 139 R A +L Q++ +P + A+ L IE Y + L Sbjct: 13 REPATVLGISPDQLLDFSANINPLGMPVSVKRAL---IDNLDCIERY----PDADYFHLH 65 Query: 140 AAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQ 199 A+A+ + + +G I + + V P + Y + Sbjct: 66 QALARHHQ----VPASWILAGNGETESIFTVASGLKPRRAMIV-TPGFAEYGRALA---- 116 Query: 200 TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV----GRTDIIFFCSPNNPTGAAATREQL 255 Q I +G+ + + D +F C+PNNPTG R L Sbjct: 117 --------QSGCEIRRWSLREADGWQLTDAILEALTPDLDCLFLCTPNNPTGLLPERPLL 168 Query: 256 TQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEV--AMETASFSKYAGFTGVR 313 + + K ++ D A+ ++ P IP ++ S +K+ G+R Sbjct: 169 QAIADRCKSLNINLILDEAFIDFI----PHETGFIPALKDNPHIWVLRSLTKFYAIPGLR 224 Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY 373 LG+ V + + + ++ L + + Sbjct: 225 LGYLVNSDDAAMARMRRQQMPW---------SVNALAALAGEVALQDSAWQ--QATWHWL 273 Query: 374 KENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPG 433 +E L A Y+ + + D+ +L + ++ + + Sbjct: 274 REEGARFYQALCQLPLLTVYPGRANYLLLRC-EREDIDLQRRLLTQ-RILIRSCANYPGL 331 Query: 434 GEGFVRVSA--FGHRENILEACR 454 + RV+ E +L A R Sbjct: 332 DSRYYRVAIRSAAQNERLLAALR 354 >3IF2-A nrPDB Length = 444 Score = 132 bits (333), Expect = 2e-31, Method: Composition-based stats. Identities = 65/381 (17%), Positives = 131/381 (34%), Gaps = 69/381 (18%) Query: 129 YGAEQGAKPLRAAIAKTFYGGLG--IGDDDVFVSDGAKCDISRLQVMFGSNVTI------ 180 Y QG A+ F + +++ +++G++ L +FG + Sbjct: 79 YSNPQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFG-GAFVNEHSQD 137 Query: 181 --------AVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFF------- 225 ++ P P Y+ S + + F + + + E GFF Sbjct: 138 KESKSVDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTH---DGEEGFFKYRVDFE 194 Query: 226 --PDLSTVGRTDIIFFCS--PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAM---- 277 +L + I C P NPTG T E++ L E AK+ ++ D+AY M Sbjct: 195 ALENLPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYGMPFPN 254 Query: 278 YMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNR 337 + D + + S SK G G+R G V K++ + Sbjct: 255 IIYSDAH------LNWDNNTILCFSLSKI-GLPGMRTGIIVADAKVIEAVSA-------- 299 Query: 338 IICTCFNGASNISQAGA---LACLTPEGLEAMHKVIGFYKENT----NIIIDTFTSLGYD 390 + N A A L + +++ FY++ ++ Sbjct: 300 -MNAVVNLAPTRFGAAIATPLVANDRIKQLSDNEIKPFYQKQATLAVKLLKQALGDYPLM 358 Query: 391 VYGGKNAPYVWVHFPNQ--SSWDVFAEILEKTHVVTTPGSGFGPG--------GEGFVRV 440 ++ + A ++W+ F + S+ D++ E L+ + P F PG +R+ Sbjct: 359 IHKPEGAIFLWLWFKDLPISTLDLY-ERLKAKGTLIVPSEYFFPGVDVSDYQHAHECIRM 417 Query: 441 SAFGHRENILEACRRFKQLYK 461 S + +++ + ++ + Sbjct: 418 SIAADEQTLIDGIKVIGEVVR 438 >3GET-A nrPDB Length = 365 Score = 132 bits (332), Expect = 3e-31, Method: Composition-based stats. Identities = 58/367 (15%), Positives = 131/367 (35%), Gaps = 52/367 (14%) Query: 91 AQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGL 150 +VI L + P + + A++ Y + L++ +A+ + Sbjct: 30 KEVIKLASNENPFGTPPKAIECLRQNANKA------HLYPDDSMI-ELKSTLAQKYK--- 79 Query: 151 GIGDDDVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 + ++++ + G+ I + S ++ Y + G + T Sbjct: 80 -VQNENIIIGAGSDQVIEFAIHSKLNSKNAFLQAGVTFAMYEIYAKQCGAK-CYKTQSIT 137 Query: 210 YGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSII 269 + E+ + + +IF C PNNP G + T+ ++ + ++ Sbjct: 138 HNLDEFKKLYETHK--------DEIKLIFLCLPNNPLGECLDASEATEFIKGVNE-DCLV 188 Query: 270 VYDSAYAMYMSDDNPRSIFE---IPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYS 326 V D+AY + S + + E + + + +FSK G G+R+G+ + ++ + Sbjct: 189 VIDAAYNEFASFKDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIANANIISA 248 Query: 327 DGFPVAKDFNRIICTCFNGASNISQAGALACL-----TPEGLEAMHKVIGFYKENTNIII 381 + + FN SN++ A+A + T + LE + YKE Sbjct: 249 -FYKLRAPFN---------VSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAK--- 295 Query: 382 DTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVS 441 + ++ F ++S D+ ++L+K ++ G +R++ Sbjct: 296 ----KHNIKII-DSYTNFITYFFDEKNSTDLSEKLLKKGIII----RNLKSYGLNAIRIT 346 Query: 442 AFGHREN 448 EN Sbjct: 347 IGTSYEN 353 >6HNB-A nrPDB Length = 491 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 77/433 (17%), Positives = 135/433 (31%), Gaps = 84/433 (19%) Query: 97 GIGDTTEPIPEVITSAMAKKAHEL---STIEGYSGYGAEQGAKPLRAAIAKT--FYGGLG 151 GIG E + K A + + YG+ G I + + Sbjct: 70 GIGAPIEGENKTTIEVFKKAADNVPDQIELARSLQYGSTFGLPEFLQFIKEHTDMVHKVP 129 Query: 152 IGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKY 210 + DV VS G L+ TI V++ ++ + ++S+ G + ++ Sbjct: 130 YENWDVIVSVGNTEAWDSTLRTFCSKGDTILVEEYTFSSALESANGQG-VNTVPVTMDEF 188 Query: 211 GNIEYMRCTPENGFFPDLSTVGRTDIIF-FCSPNNPTGAAATREQLTQLVEFAKKNGSII 269 G I + + + ++ C+ NPTG++ + E+ Q+ + A K +I Sbjct: 189 GIIPEKLEELMSRW-----VGNKPKFLYTICTGQNPTGSSLSAERRKQIYDIACKYDFLI 243 Query: 270 VYDSAY-----AMYMSDDNPRSIFEIPGAEE----------------VAMETASFSKYAG 308 + D Y Y D R + +E + SFSK Sbjct: 244 IEDEPYYFLQMETYTKDKAAREGKAVHDHDEFLKALVPSFISLDVEGRVVRLDSFSKVLA 303 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTP----EGLE 364 G+RLGW V K LL + + R+ S S+A A A L L+ Sbjct: 304 -PGLRLGWIVGQKDLL--------ERYVRLHEVSVQNPSGFSEALANALLRKWGHSGYLD 354 Query: 365 AMHKVIGFYKENTNIIIDTFTSLGYD----VYGGKNAPYVWVHFPNQSSWDVFAEILE-- 418 + + Y ++ ID + V + S + E LE Sbjct: 355 WLIGLRAEYTHKRDVAIDALDQFVPKEVSSFNPPVAGMFFTVTL-DASKHPKYKEFLEDP 413 Query: 419 ------------KTHVVTTPGSGFGPGGEG-----------------FVRVSAFG-HREN 448 K + PGS F G+ F R + + Sbjct: 414 LKVEAAVHEQAIKQGCLLAPGSWFKAEGQSSPPQKNLPANPSHKTHIFFRGTYAAVPLDQ 473 Query: 449 ILEACRRFKQLYK 461 ++ +F + + Sbjct: 474 LVVGLEKFGKAVR 486 >1IJI-A nrPDB Length = 356 Score = 128 bits (321), Expect = 6e-30, Method: Composition-based stats. Identities = 58/324 (17%), Positives = 118/324 (36%), Gaps = 41/324 (12%) Query: 140 AAIAKTFYGGLGIGDDDVFVSDGAKCDISRL-QVMFGSN-VTIAVQDPSYPAYVDSSVIM 197 A+ + + G+ + V VS GA I L + I P+Y Y S+ + Sbjct: 61 KAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETI 120 Query: 198 GQTGQFNTDVQKYGNIEYMRCTPENGFFPDLS----TVGRTDIIFFCSPNNPTGAAATRE 253 G +E + + DL + +++ CSPNNPTG + Sbjct: 121 G--------------VECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQ 166 Query: 254 QLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVR 313 L+E + +I+V D AY + S+ + SK G+R Sbjct: 167 DFRTLLELTRGK-AIVVADEAYIEFCPQA---SLAGWLAEYPHLAILRTLSKAFALAGLR 222 Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY 373 G+T+ ++++ + + + ++ ++ A L+P+G+ AM + + Sbjct: 223 CGFTLANEEVI---------NLLMKVIAPYPLSTPVADIAA-QALSPQGIVAMRERVAQI 272 Query: 374 KENTNIIIDTFTSLG-YDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGP 432 +I + + Y+ F ++S VF + ++ ++ P Sbjct: 273 IAEREYLIAALKEIPCVEQVFDSETNYILARF--KASSAVFKSLWDQGIILRDQNK--QP 328 Query: 433 GGEGFVRVSAFGHRE--NILEACR 454 G +R++ E +++A R Sbjct: 329 SLSGCLRITVGTREESQRVIDALR 352 >3HDO-A nrPDB Length = 360 Score = 126 bits (317), Expect = 2e-29, Method: Composition-based stats. Identities = 60/367 (16%), Positives = 125/367 (34%), Gaps = 45/367 (12%) Query: 94 ISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG 153 I L + P + A+ EL ++ LR + + G Sbjct: 29 IKLNTNENPYPPSPEVVKAI---LEELGPDGAALRIYPSASSQKLREVAGELY----GFD 81 Query: 154 DDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGN 212 + +++G+ ++ ++ I PSY Y + + G V+ +G Sbjct: 82 PSWIIMANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLAEVQGAR------VRTFGL 135 Query: 213 IEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYD 272 R + + F +PN P G + E + +L ++V D Sbjct: 136 TGDFRIAGFPERY-------EGKVFFLTTPNAPLGPSFPLEYIDELARRCAG---MLVLD 185 Query: 273 SAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVA 332 YA + + E+ E + T + SK G+R+G + +++ + Sbjct: 186 ETYAEFAESN----ALELVRRHENVVVTRTLSKSYSLAGMRIGLAIARPEVIAA------ 235 Query: 333 KDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVY 392 ++I ++QA +A L + + + +E S+GYDV Sbjct: 236 --LDKIRDH--YNLDRLAQAACVAALRDQA--YLSECCRRIRETREWFTTELRSIGYDVI 289 Query: 393 GGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEA 452 + Y++ P++ V+ + + V+ S P +R+S RE + + Sbjct: 290 PSQGN-YLFATPPDRDGKRVYDGLYAR-KVLVRHFS--DPLLAHGMRISIGT-REEMEQT 344 Query: 453 CRRFKQL 459 K++ Sbjct: 345 LAALKEI 351 >1YAA-A nrPDB Length = 412 Score = 124 bits (310), Expect = 1e-28, Method: Composition-based stats. Identities = 85/421 (20%), Positives = 132/421 (31%), Gaps = 53/421 (12%) Query: 73 LFPEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSG 128 L P+ + A + LGIG D +P A K H S+ Sbjct: 11 LPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIHNDSSYN--HE 68 Query: 129 YGAEQGAKPLRAAIAKTFYGGL--GIGDDDVFVS-----DGAKCDISRLQVMFGSNVTIA 181 Y G L + AK +G + +D V GA ++ F + + Sbjct: 69 YLGITGLPSLTSNAAKIIFGTQSDALQEDRVISVQSLSGTGALHISAKFFSKFFPDKLVY 128 Query: 182 VQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCS 241 + P++ ++ G + NGF + I S Sbjct: 129 LSKPTWANHMAIFENQGLKTATYPYW-----ANETKSLDLNGFLNAIQKAPEGSIFVLHS 183 Query: 242 -PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEV---- 296 +NPTG T EQ Q+V+ I ++D+AY + + D + + + E Sbjct: 184 CAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLGVEKLSTV 243 Query: 297 --AMETASFSKYAGFTGVRLGW--TVIPKKLLYSDGFP-VAKDFNRIICTCFNGASNISQ 351 SF+K AG G R+G + K+ P V +II + + Sbjct: 244 SPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVSNPPAYGA 303 Query: 352 AGALACL-TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 L TPE E HK + + + P W H NQ Sbjct: 304 KIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKL----GTPGNWDHIVNQCGM 359 Query: 411 DVFA-------EILEKTHVVTTPGSGFGPGGEGFVRVSAF----GHRENILEACRRFKQL 459 F + LE+TH V SG R S G+ E + +A + Sbjct: 360 FSFTGLTPQMVKRLEETHAVYLVASG---------RASIAGLNQGNVEYVAKAIDEVVRF 410 Query: 460 Y 460 Y Sbjct: 411 Y 411 >6EZL-A nrPDB Length = 404 Score = 121 bits (304), Expect = 5e-28, Method: Composition-based stats. Identities = 64/342 (18%), Positives = 110/342 (32%), Gaps = 31/342 (9%) Query: 103 EPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDG 162 P P + K L + Y G P + G + ++V G Sbjct: 46 HPYPLNVVR---KAEQRLLEMNADKEYLPMSGYAPFIEE-SLKIAYGDSVARENVVGIQG 101 Query: 163 --AKCDISR----LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY- 215 +S L + + + + DP++P + TD++KY + Sbjct: 102 LSGTGSLSIGACFLARVLSRDTPVYISDPTWPNHYAVMAAAN-----LTDLRKYRYYDNA 156 Query: 216 MRCTPENGFFPDLSTVGRTDIIFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSA 274 RC +G DL+ I+ +NPTG T EQ +++E + I +DSA Sbjct: 157 KRCIDFDGLLEDLNGAPEGSIVILHACAHNPTGMDPTHEQWAKILEVFQARRLIPFFDSA 216 Query: 275 YAMYMS---DDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPV 331 Y Y + D++ SI + S+SK G R+G I + Sbjct: 217 YQGYATGSLDNDAYSIRLFARQGMEMLLAQSYSKNMGLYAERVGVCSIVTA-NPKKAPLI 275 Query: 332 AKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDV 391 I+ + ++ + +A L E + + +++ +L YD Sbjct: 276 KSQLETIVRSQYSTPP--AHGARVAYLVLSDPELRAGWEQELRVMSTRVLEMRQAL-YDG 332 Query: 392 YGGKNAPYVWVH-------FPNQSSWDVFAEILEKTHVVTTP 426 P W H F E L + V P Sbjct: 333 LKRLGTPGSWEHIIQQVGMFSYLGLTKAQCEKLIERRVFVLP 374 >3P1T-A nrPDB Length = 337 Score = 121 bits (303), Expect = 7e-28, Method: Composition-based stats. Identities = 62/309 (20%), Positives = 102/309 (33%), Gaps = 43/309 (13%) Query: 142 IAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTG 201 + + +D++ + G R+ F S + P + Y + G Sbjct: 56 VMRKLAEHFSCPEDNLMLVRGIDECFDRISAEFSS-MRFVTAWPGFDGYRARIAVSG--- 111 Query: 202 QFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEF 261 + E DL+ V R D + +P+NPTG A + +L QL + Sbjct: 112 --------LRHFEIGLTDDLLLDPNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLRQR 163 Query: 262 AKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG--AEEVAMETASFSKYAGFTGVRLGWTVI 319 A K ++ D Y Y S F G E + SFSK G G+RLG Sbjct: 164 AGK----LLIDETYVDY-------SSFRARGLAYGENELVFRSFSKSYGLAGLRLGALFG 212 Query: 320 PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNI 379 P +L+ + R C G ++ AL + + Sbjct: 213 PSELIAA--------MKRKQWFCNVGTLDL---HALEAALDNDRAREAHIAKTLAQRRR- 260 Query: 380 IIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVR 439 + D LGY V + A +V V ++ + L + + FG +R Sbjct: 261 VADALRGLGYRVASSE-ANFVLV---ENAAGERTLRFLRERGIQVKDAGQFGL--HHHIR 314 Query: 440 VSAFGHREN 448 +S +N Sbjct: 315 ISIGREEDN 323 >1AY8-A nrPDB Length = 394 Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats. Identities = 71/410 (17%), Positives = 122/410 (29%), Gaps = 48/410 (11%) Query: 70 AGYLFPEIARRRSA---HLLKYPDAQVISLGIG---DTTEPIPEVITSAMAKKAHELSTI 123 G L P+ + A P I LG+G D T P I A+ + Sbjct: 2 LGNLKPQAPDKILALMGEFRADPRQGKIDLGVGVYKDATGHTP--IMRAVHAAEQRMLET 59 Query: 124 EGYSGYGAEQGAKPLRAAIAKT-FYGGLGIGDDDVFVSDGAKCDI---SRLQVMFGSNVT 179 E Y G + A+ + GL + G + L M ++ Sbjct: 60 ETTKTYAGLSGEPEFQKAMGELILGDGLKSETTATLATVGGTGALRQALELARMANPDLR 119 Query: 180 IAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFF 239 + V DP++P +V MG +Y + E R G DL+ + D++ Sbjct: 120 VFVSDPTWPNHVSIMNFMG----LPVQTYRYFDAE-TRGVDFEGMKADLAAAKKGDMVLL 174 Query: 240 C-SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEV-- 296 +NPTGA T +Q ++ +K G++ + D AY + D Sbjct: 175 HGCCHNPTGANLTLDQWAEIASILEKTGALPLIDLAYQGF-GDGLEEDAAGTRLIASRIP 233 Query: 297 -AMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGAL 355 + AS SK G R G + + + ++ + Sbjct: 234 EVLIAASCSKNFGIYRERTGCLLALCAD-AATRELAQGAMAFLNRQTYSFPPFH--GAKI 290 Query: 356 ACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAE 415 E + + + ++ L + S D F Sbjct: 291 VSTVLTTPELRADWMAELEAVRSGMLRLREQLA-------------GELRDLSGSDRFGF 337 Query: 416 ILEKTHVVTTPG----------SGFGPGGEGFVRVSAFGHRENILEACRR 455 + E + + G FG G R++ G +N + R Sbjct: 338 VAEHRGMFSRLGATPEQVKRIKEEFGIYMVGDSRINIAGLNDNTIPILAR 387 >3FFH-A nrPDB Length = 363 Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats. Identities = 63/373 (16%), Positives = 128/373 (34%), Gaps = 44/373 (11%) Query: 80 RRSAHLLKYPDAQVI-SLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPL 138 +R ++ I L + + K A + + + A L Sbjct: 20 KREEEVMAELGLTKITKLSSNENPLGTSK-------KVAAIQANSSVETEIYPDGWASSL 72 Query: 139 RAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQ-VMFGSNVTIAVQDPSYPAYVDSSVIM 197 R +A + + ++++ + G I L V+ + + P++ Y +++I Sbjct: 73 RKEVADFYQ----LEEEELIFTAGVDELIELLTRVLLDTTTNTVMATPTFVQYRQNALIE 128 Query: 198 GQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQ 257 G + +Q + G + +T I++ C+PNNPTG + Sbjct: 129 GAEVREIPLLQDGEH-------DLEGMLNAIDE--KTTIVWICNPNNPTGNYIELADIQA 179 Query: 258 LVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWT 317 ++ ++V D AY Y++ P ++ + + T +FSK G R+G+ Sbjct: 180 FLDRVPS-DVLVVLDEAYIEYVT-PQPEKHEKLVRTYKNLIITRTFSKIYGLASARVGYG 237 Query: 318 VIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGL--EAMHKVIGFYKE 375 + K+++ I+ FN S I Q A+ + + E K+ Sbjct: 238 IADKEIIRQLN---------IVRPPFNTTS-IGQKLAIEAIKDQAFIGECRTSNANGIKQ 287 Query: 376 NTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGE 435 F + N +V + ++ LEK +T G+ G Sbjct: 288 Y-EAFAKRFEKVKLY---PANGNFVLIDLGIEAGTIF--SYLEKNGYITRSGAALGFPTA 341 Query: 436 GFVRVSAFGHREN 448 VR++ +N Sbjct: 342 --VRITIGKEEDN 352 >6HNV-A nrPDB Length = 524 Score = 118 bits (296), Expect = 4e-27, Method: Composition-based stats. Identities = 61/386 (15%), Positives = 117/386 (30%), Gaps = 62/386 (16%) Query: 128 GYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGAKCDIS-RLQVMFGSNVTIAVQD 184 Y A +G PL D +VF++ GA ++ V I V++ Sbjct: 129 QYAAVEGHAPLLQFARDFIIRTHKPNYDDWNVFITTGASDGLNKAADVFLDDGDVILVEE 188 Query: 185 PSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST----VGRTDIIF-F 239 ++ ++ S G + + + + T + + + ++ Sbjct: 189 FTFSPFLRFSDNAGAK-AVPVKINFDNDSDGIDLTQFVDLLENWEKHYPNLPKPKALYTI 247 Query: 240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA----------------------- 276 + NPTG + E ++ + A K I+ D Y Sbjct: 248 ATGQNPTGFTQSLEFRKKIYDLAVKYDFAIIEDDPYGYLTLPKYEKPNIGGSGSGNNELK 307 Query: 277 ------MYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFP 330 Y+ + S E+ + +FSK G+RLG+ V K+++ + Sbjct: 308 NDLEIDDYLKNHLTPSYLEL-DTTGRVLRVETFSKLFA-PGLRLGFIVGHKEVIDAVKNY 365 Query: 331 VAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIII------DTF 384 +N+ Q LE + K+ Y ++++ + Sbjct: 366 SDVVNRGASGLTQTIVNNVIQENFKG--VDGWLEWILKMRLNYSYRKDLLLYSIFESQAY 423 Query: 385 TSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEI------LEKTHVVTTPGSG------FGP 432 DV K +V DV ++ L ++ PG F Sbjct: 424 KKGYVDVIDPKAGMFVTFKINLPKDVDVLQKMKLLLWKLISYGILVVPGYNMTVDLEFSK 483 Query: 433 GGEGFVRVSAFG--HRENILEACRRF 456 F R+ + E ILE+ +R Sbjct: 484 DRSNFFRLCYALANNDEEILESGKRL 509 >3LY1-A nrPDB Length = 354 Score = 118 bits (296), Expect = 4e-27, Method: Composition-based stats. Identities = 52/318 (16%), Positives = 106/318 (33%), Gaps = 30/318 (9%) Query: 145 TFYGGLGIGDDDVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQF 203 + + ++ G+ I + ++ + + + +Y + I G Sbjct: 59 KLAAHHQVEAPSILLTAGSSEGIRAAIEAYASLEAQLVIPELTYGDGEHFAKIAGMKVTK 118 Query: 204 NTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAK 263 + + G ++ I++ +PNNPTG + + + +K Sbjct: 119 VKMLDNWA-------FDIEGLKAAVAAYSGPSIVYLVNPNNPTGTITPADVIEPWIA-SK 170 Query: 264 KNGSIIVYDSAYAMYMSDDNPRSIFE-IPGAEEVAMETASFSKYAGFTGVRLGWTVIPKK 322 ++ + D AYA +++D RSI I E + +FSK G+R+G+ V Sbjct: 171 PANTMFIVDEAYAEFVNDPRFRSISPMITQGAENIILLKTFSKIHAMAGMRVGYAVAHPT 230 Query: 323 LLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIID 382 ++ G VA + F+G ALA + K I++ Sbjct: 231 VIALMGRYVAGE-----KINFSGVD-----AALASMNDSAFITYSKKSNDVS--RQILLK 278 Query: 383 TFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSA 442 L + V + + V+ G F P + + R+S Sbjct: 279 ALEDLKLPYLPSEGNF---VFHQLVVPLKDYQTHMADAGVLI--GRAF-PPADNWCRISL 332 Query: 443 FGHREN--ILEACRRFKQ 458 +E + + R F++ Sbjct: 333 GTPQEMQWVADTMREFRK 350 >4JE5-A nrPDB Length = 503 Score = 118 bits (295), Expect = 6e-27, Method: Composition-based stats. Identities = 83/496 (16%), Positives = 133/496 (26%), Gaps = 119/496 (23%) Query: 71 GYLFPEIARRRSAHLLK-----YPDAQVISLGIGDT------------TEPIPEV----- 108 YLF + R LK + D +I LG G P P Sbjct: 13 SYLFSDETNARKPSPLKTCIHLFQDPNIIFLGGGLPLKDYFPWDNLSVDSPKPPFPQGIG 72 Query: 109 ------------ITSAMAKKAHELSTIEGYS---GYGAEQGAKPLRAAIAKTFY--GGLG 151 + A K+ S S YG G L I L Sbjct: 73 APIDEQNCIKYTVNKDYADKSANPSNDIPLSRALQYGFSAGQPELLNFIRDHTKIIHDLK 132 Query: 152 IGDDDVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKY 210 D DV + G S L+V I V+ S+ + + S+ G F + Sbjct: 133 YKDWDVLATAGNTNAWESTLRVFCNRGDVILVEAHSFSSSLASAEAQGVI-TFPVPIDAD 191 Query: 211 GNIEYMRCTPENGFFPDLSTVGRTDIIF-FCSPNNPTGAAATREQLTQLVEFAKKNGSII 269 G I + P + +++ + NPTG + + + + A+K +I Sbjct: 192 GIIPEKLAKVMENWTP---GAPKPKLLYTIPTGQNPTGTSIADHRKEAIYKIAQKYDFLI 248 Query: 270 VYDSAYAMYMSDDNPRSI------------------------FEIPGAEEVAMETASFSK 305 V D Y + + + F E + SFSK Sbjct: 249 VEDEPYYFLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFLSLDTEGRVIRMDSFSK 308 Query: 306 YAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACL----TPE 361 G RLGW K+L K + + + +Q A L Sbjct: 309 VLA-PGTRLGWITGSSKIL--------KPYLSLHEMTIQAPAGFTQVLVNATLSRWGQKG 359 Query: 362 GLEAMHKVIGFYKENTNIIIDTFTSL-----GYDVYGGKNAPYVWVHFPNQSSWDVFAEI 416 L+ + + Y + ID + + + V+ + + Sbjct: 360 YLDWLLGLRHEYTLKRDCAIDALYKYLPQSDAFVINPPIAGMFFTVNIDASVHPEFKTKY 419 Query: 417 --------------LEKTHVVTTPGSGFGPGGEG-----------------FVRVSAFG- 444 + + V+ PGS F GE F R + Sbjct: 420 NSDPYQLEQSLYHKVVERGVLVVPGSWFKSEGETEPPQPAESKEVSNPNIIFFRGTYAAV 479 Query: 445 HRENILEACRRFKQLY 460 E + E +R Sbjct: 480 SPEKLTEGLKRLGDTL 495 >3PD6-B nrPDB Length = 401 Score = 117 bits (294), Expect = 7e-27, Method: Composition-based stats. Identities = 59/356 (16%), Positives = 119/356 (33%), Gaps = 29/356 (8%) Query: 83 AHLLKYPDAQVISLGIG--DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 + +++ ++LG+G P + ++ K +++ Y G Sbjct: 20 EAFKRDTNSKKMNLGVGAYRDDNGKP-YVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCK 78 Query: 141 AIAKT--------FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVD 192 A A+ G + + + + S LQ F + + + PS+ + Sbjct: 79 ASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTP 138 Query: 193 SSVIMGQTGQFNTDVQKYGNIEYMRCT-PENGFFPDLSTVGRTDIIFF-CSPNNPTGAAA 250 G +Q Y + C +G D+S + ++ +NPTG Sbjct: 139 IFRDAGM------QLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDP 192 Query: 251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAME---TASFSKYA 307 EQ ++ KK +D AY + S D + + + E + S++K Sbjct: 193 RPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNM 252 Query: 308 GFTGVRLG-WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 G G R+G +TV+ K + V +I ++ +A + Sbjct: 253 GLYGERVGAFTVVCKDAEEAK--RVESQLKILIRPLYSNPP--LNGARIAATILTSPDLR 308 Query: 367 HKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHV 422 + + K + II T L ++ + + + W H +Q L+ V Sbjct: 309 KQWLQEVKGMADRIISMRTQLVSNLKK-EGSSHNWQHITDQIGM-FCFTGLKPEQV 362 >3G7Q-A nrPDB Length = 417 Score = 117 bits (294), Expect = 7e-27, Method: Composition-based stats. Identities = 63/333 (18%), Positives = 114/333 (34%), Gaps = 40/333 (12%) Query: 149 GLGIGDDDVFVSDGAKCDISRLQVMFG----SNVTIAVQDPSYPAYVDSSVIMGQTGQFN 204 G I ++ +++G++ L +F T V P P Y+ + + F Sbjct: 93 GWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDLFV 152 Query: 205 TDVQKYGNIEYMRCTPENGF-----FPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLV 259 + + PE F F L T +I P NPTG T E+L +L Sbjct: 153 SARP------NIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLD 206 Query: 260 EFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319 A ++ +V D+AY + P + S SK G G R G + Sbjct: 207 RLANQHNIPLVIDNAYG--VPFPGIIFSEARPLWNPNIILCMSLSK-LGLPGSRCGIIIA 263 Query: 320 PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVI--GFYKENT 377 K + + + N II G A + L + + + FY + Sbjct: 264 NDKTITA-----IANMNGIISLAPGGM---GPAMMCEMIKRNDLLRLSETVIKPFYYQRV 315 Query: 378 N----IIIDTFTSLGYDVYGGKNAPYVWVHFPNQS-SWDVFAEILEKTHVVTTPGSGFGP 432 II + ++ + A ++W+ F + + ++ + L+ V+ PG F P Sbjct: 316 QQTIAIIRRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFP 375 Query: 433 G-------GEGFVRVSAFGHRENILEACRRFKQ 458 G +R++ + I + + Sbjct: 376 GLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAE 408 >3EUC-A nrPDB Length = 367 Score = 115 bits (287), Expect = 5e-26, Method: Composition-based stats. Identities = 60/359 (16%), Positives = 119/359 (33%), Gaps = 39/359 (10%) Query: 93 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGI 152 ++ L + +P + S +A + E++ + Y ++ LRA + + G+ Sbjct: 32 LVKLDAMENPYRLPPALRSELAARLGEVAL----NRY-PVPSSEALRAKLKEVMQVPAGM 86 Query: 153 GDDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYG 211 +V + +G+ IS L + P + Y S+ G + Sbjct: 87 ---EVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQFAGLEFVGVPLRADFT 143 Query: 212 NIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKN--GSII 269 P I++ PNNPTG + +V A+ + S++ Sbjct: 144 LDRGAMLAAMAEHQP--------AIVYLAYPNNPTGNLFDAADMEAIVRAAQGSVCRSLV 195 Query: 270 VYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGF 329 V D AY + + S + + SK G G+RLG+ + L Sbjct: 196 VVDEAYQPFAQE----SWMSRLTDFGNLLVMRTVSK-LGLAGIRLGYVAGDPQWLE---- 246 Query: 330 PVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGY 389 + +++A AL L E + + + + + + + + G Sbjct: 247 ------QLDKVRPPYNVNVLTEATALFAL--EHVAVLDEQAAQLRAERSRVAEGMAAHGG 298 Query: 390 DVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN 448 A ++ P+ + F +L + V+ S P +RV+ EN Sbjct: 299 VTVFPSAANFLLARVPDAAQT--FDRLLAR-KVLIKNVSKMHPLLANCLRVTVSTPEEN 354 >3RQ1-A nrPDB Length = 418 Score = 115 bits (287), Expect = 5e-26, Method: Composition-based stats. Identities = 71/415 (17%), Positives = 128/415 (30%), Gaps = 24/415 (5%) Query: 63 SNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIG-DTTEPIPEVITSAMAKKAHELS 121 + + + A + A + V++ +G E V + ++ LS Sbjct: 10 KHAKGKKLKDVIFVTAGQAQADAKENGRENVVNGTLGAIHDEEGNLVFLKTVKEEYLSLS 69 Query: 122 TIEGYSGYGAEQGAKPLRAAIAKT-FYGGLGIGDDDVFVSDGAKCDISRL-QVMFGSNVT 179 E + GY G A K F G + G I L Sbjct: 70 DSE-HVGYAPIAGIPDFLCAAEKECFGNFRPEGHIRSIATAGGTGGIHHLIHNYTEPGDE 128 Query: 180 IAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFF 239 + D + AY VI TG+ + +L+ ++ F Sbjct: 129 VLTADWYWGAYR---VICSDTGRTLVTYSLFDEHNNFNHEAFQNRVNELAAKQTNVVVIF 185 Query: 240 CSP-NNPTGAAATREQLTQLVEFAK------KNGSIIVYDSAYAMYMSDDNPRSIF---- 288 +P NNPTG + + ++ F K +N II D AY Y + + F Sbjct: 186 NTPGNNPTGYSIEDKDWDSILNFLKDLVAIGRNNVIIGIDVAYLDYSGEKDEVRAFFNKF 245 Query: 289 EIPGAEEVAMETASFSKYAGFTGVRLGWTVI--PKKLLYSDGFPVAKDFNRIICT--CFN 344 E + S SK G R+G + + + + F V K +R + C Sbjct: 246 SHLPKEILTCVCYSLSKGFTMYGQRVGAMIGISDDEEIADEFFEVNKSTSRATWSNICRP 305 Query: 345 GASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHF 404 ++ A E + ++ +I +G + + ++ Sbjct: 306 AMRTMANIVADPAKFKEYEAERNCYYQLIRDRADIFKQEAAQVGLPMLPYRGGFFI--TI 363 Query: 405 PNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 P S+ + E+ ++ V +G G + G E I A + +L Sbjct: 364 PTDSANAICEELKKEHIYVIALANGIRIAACGIPKCQMTGLAEKIYNAMKSLGKL 418 >1TAR-A nrPDB Length = 401 Score = 112 bits (281), Expect = 3e-25, Method: Composition-based stats. Identities = 65/356 (18%), Positives = 123/356 (34%), Gaps = 29/356 (8%) Query: 83 AHLLKYPDAQVISLGIG--DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 + +++ ++LG+G P + + + K ++ + Y G Sbjct: 20 EAFKRDTNSKKMNLGVGAYRDDNGKP-YVLNCVRKAEAMIAAKKMDKEYLPIAGLADFTR 78 Query: 141 AIAKT--------FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVD 192 A A+ F G + + + + + LQ F + + + PS+ + Sbjct: 79 ASAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFFKFSRDVYLPKPSWGNHTP 138 Query: 193 SSVIMGQTGQFNTDVQKYGNIEYMRCT-PENGFFPDLSTVGRTDIIFF-CSPNNPTGAAA 250 G +Q Y + C+ G D+S + II +NPTG Sbjct: 139 IFRDAG------LQLQAYRYYDPKTCSLDFTGAMEDISKIPEKSIILLHACAHNPTGVDP 192 Query: 251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET---ASFSKYA 307 +EQ +L KK + +D AY + S D R + + E ++ S++K Sbjct: 193 RQEQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGIDVVLSQSYAKNM 252 Query: 308 GFTGVRLG-WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 G G R G +TVI + + V +I ++ +A L E Sbjct: 253 GLYGERAGAFTVICRDAEEAK--RVESQLKILIRPMYSNPP--MNGARIASLILNTPELR 308 Query: 367 HKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHV 422 + + K + II T L ++ + + + W H +Q L+ V Sbjct: 309 KEWLVEVKGMADRIISMRTQLVSNLKK-EGSSHNWQHITDQIGM-FCFTGLKPEQV 362 >4F5M-A nrPDB Length = 406 Score = 111 bits (277), Expect = 6e-25, Method: Composition-based stats. Identities = 63/383 (16%), Positives = 123/383 (32%), Gaps = 36/383 (9%) Query: 65 MSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIG---DTTEPIPEVITSAMAKKAHELS 121 + A P + + P I+LGIG D T P + +++ K L Sbjct: 12 FENITAAPADPILGLADLFRADERPGK--INLGIGVYKDETGKTP--VLTSVKKAEQYLL 67 Query: 122 TIEGYSGYGAEQGAKPL-RAAIAKTFYGGLGIGDD---DVFVSDGAKCDISRLQVMFGSN 177 E Y G R F G + +D + G + N Sbjct: 68 ENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKN 127 Query: 178 V---TIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMR-CTPENGFFPDLSTVGR 233 + V +PS+P + G +V++Y + + L+ Sbjct: 128 TSVKRVWVSNPSWPNHKSVFNSAG------LEVREYAYYDAENHTLDFDALINSLNEAQA 181 Query: 234 TDIIFFC-SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS--DDNPRSIFEI 290 D++ F +NPTG T EQ L + + + G + ++D AY + +++ + Sbjct: 182 GDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRAF 241 Query: 291 PGAEEVAMETASFSKYAGFTGVRLGWT--VIPKKLLYSDGFPVAKDFNR--IICTCFNGA 346 + + +S+SK G R+G V F K R +GA Sbjct: 242 AAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHGA 301 Query: 347 SNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLG----YDVYGGKNAPYVWV 402 S ++ + L + + + + + ++T G + +N + + Sbjct: 302 SVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFS 361 Query: 403 HFPNQSSWDVFAEILEKTHVVTT 425 + + + E+ V Sbjct: 362 GL----TKEQVLRLREEFGVYAV 380 >3FSL-A nrPDB Length = 397 Score = 111 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 66/319 (20%), Positives = 110/319 (34%), Gaps = 24/319 (7%) Query: 83 AHLLKYPDAQVISLGIG---DTTEPIPEVITSAMAKKAHEL-STIEGYSGYGAEQGAKPL 138 + P + ++L IG + IP++ A+A+ L + G S Y +G Sbjct: 18 ERFKEDPRSDKVNLSIGLYYNEDGIIPQL--QAVAEAEARLNAQPHGASLYLPMEGLNCY 75 Query: 139 RAAIAKTFYGG----LGIGDDDVFVSDGAKCDISRLQVMFG---SNVTIAVQDPSYPAYV 191 R AIA +G L + G + + V DP++ Sbjct: 76 RHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFPESGVWVSDPTW---E 132 Query: 192 DSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFC-SPNNPTGAAA 250 + I G + Y E N L T+ I+ +NPTGA Sbjct: 133 NHVAIFAGAGFEVSTYPWYD--EATNGVRFNDLLATLKTLQAGSIVLLHPCCHNPTGADL 190 Query: 251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMS--DDNPRSIFEIPGAEEVAMETASFSKYAG 308 T +Q ++E K I D AY + + +++ +I I A A+ + SFSK Sbjct: 191 TNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPALVSNSFSKIFS 250 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHK 368 G R+G + + + G V + ++ N A L E L+A Sbjct: 251 LYGERVGGLSVMCEDAEAAG-RVLGQLKATVRRNYSSPPNFGAQVVAAVLNDEALKA--S 307 Query: 369 VIGFYKENTNIIIDTFTSL 387 + +E I+ L Sbjct: 308 WLKEVEEMRTRILAMRQEL 326 >3G0T-A nrPDB Length = 437 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 68/409 (16%), Positives = 133/409 (32%), Gaps = 47/409 (11%) Query: 83 AHLLKYPDAQVISLGIGDTTEPIPEV-ITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAA 141 +L K + + +G P P++ I + + K +++I Y G L+ Sbjct: 36 TNLEKATGTKFCRMEMGVPGLPAPQIGIETEIQKLREGVASI-----YPNLDGLPELKQE 90 Query: 142 IAKT--FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVT-----IAVQDPSYPAYVDSS 194 ++ + + I + G+ ++ DP + Sbjct: 91 ASRFAKLFVNIDIPARACVPTVGSMQGCFVSFLVANRTHKNREYGTLFIDPGFNLNKLQC 150 Query: 195 VIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQ 254 I+GQ + ++ R G+ I + +PNNPT T E+ Sbjct: 151 RILGQKFES-------FDLFEYRGEKLREKLESYLQTGQFCSIIYSNPNNPTWQCMTDEE 203 Query: 255 LTQLVEFAKKNGSIIVYDSAY------AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 L + E A K+ I++ D AY Y P + + + S SK Sbjct: 204 LRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSVANYTDNYILALSSSKAFS 263 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRI----------ICTCFNGASNISQAGALACL 358 + G R+G +I KL + + + F R+ + +GA++ +Q G A L Sbjct: 264 YAGQRIGVLMISGKLYEREYPDLEESFGRLRFGEALSSSALYALSSGATHSAQWGMAAML 323 Query: 359 TPE--GLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGK-------NAPYVWVHFPNQSS 409 G + Y I+ F G+++ K + Y V + S Sbjct: 324 KACNDGEYNFRDSVIEYGRKARIMKKMFLDNGFNIVYDKDGNEPLADGFYFTVGYKGMDS 383 Query: 410 WDVFAEILEKTHVVTTPGSGFGPGGEGFVRVS-AFGHRENILEACRRFK 457 + + + T + G +R+ + + +R + Sbjct: 384 SKLIEKFVRYGMCAITLKTT-GSKRNEAMRICTSLLPESQFPDLEKRLQ 431 >2ZY3-A nrPDB Length = 546 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 64/360 (17%), Positives = 110/360 (30%), Gaps = 73/360 (20%) Query: 156 DVFVSDGAKCDIS------RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 ++F +G ++ +L + + +A+ P + Y++ + Q + Sbjct: 167 NLFAVEGGTAAMAYIFESLKLNGLLKAGDKVAIGMPVFTPYIEIPEL-AQYALEEVAINA 225 Query: 210 YGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKN--GS 267 ++ + E D + I F +P+NP + L ++ ++ Sbjct: 226 DPSLNWQYPDSELDKLKDPA----IKIFFCVNPSNPPSVKMDQRSLERVRNIVAEHRPDL 281 Query: 268 IIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI-------- 319 +I+ D Y + D+ +S+F I E + SFSKY G TG RLG Sbjct: 282 MILTDDVYGTFA--DDFQSLFAI--CPENTLLVYSFSKYFGATGWRLGVVAAHQQNVFDL 337 Query: 320 ---------------------PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGA---- 354 P + D + G S Q Sbjct: 338 ALDKLQESEKVALDHRYRSLLPDVRSLKFIDRLVADSRAVALNHTAGLSTPQQVQMALFS 397 Query: 355 LACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNA--PYVWVHFPN------ 406 L L E E H + + + LG +NA Y + + Sbjct: 398 LFALMDEADEYKHTLKQLIRRRETTLY---RELGMPPLRDENAVDYYTLIDLQDVTAKLY 454 Query: 407 -----------QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 455 S+ D+ I ++T +V PG GFG R S E A R Sbjct: 455 GEAFSEWAVKQSSTGDMLFRIADETGIVLLPGRGFGSNRPSG-RASLANLNEYEYAAIGR 513 >3FDD-A nrPDB Length = 533 Score = 105 bits (261), Expect = 5e-23, Method: Composition-based stats. Identities = 61/360 (16%), Positives = 109/360 (30%), Gaps = 73/360 (20%) Query: 156 DVFVSDGAKCDISRL------QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 ++F +G ++ + + + +A+ P + Y++ + Q + Sbjct: 167 NLFAVEGGTAAMAYIFESMKVNGLLKAGDKVAIGMPVFTPYIEIPEL-AQYALEEVAINA 225 Query: 210 YGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKN--GS 267 + + E D + I F +P+NP L ++ + ++ Sbjct: 226 DPALNWQYPDSELDKLKDPA----IKIFFCVNPSNPPSVKMDERSLERVRKIVAEHRPDL 281 Query: 268 IIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD 327 +I+ D Y + D +S+F I A + SFSKY G TG RLG K+ ++ Sbjct: 282 MILTDDVYGTFA--DGFQSLFAICPA--NTLLVYSFSKYFGATGWRLGVVAAHKENIFDL 337 Query: 328 GF-----------------------------PVAKDFNRIICTCFNGASNISQAGA---- 354 + D + G S Q Sbjct: 338 ALGRLPESEKTALDDRYRSLLPDVRSLKFLDRLVADSRAVALNHTAGLSTPQQVQMTLFS 397 Query: 355 LACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNA--PYVWVHFPNQSSW-- 410 L L E + + + + LG +NA Y + + +S Sbjct: 398 LFALMDES-DQYKHTLKQLIRRREATL--YRELGTPPQRDENAVDYYTLIDLQDVTSKLY 454 Query: 411 ---------------DVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 455 D+ I ++T +V PG GFG R S E A R Sbjct: 455 GEAFSKWAVKQSSTGDMLFRIADETGIVLLPGRGFGSDRPSG-RASLANLNEYEYAAIGR 513 >2ZY2-A nrPDB Length = 544 Score = 105 bits (261), Expect = 5e-23, Method: Composition-based stats. Identities = 63/389 (16%), Positives = 115/389 (29%), Gaps = 86/389 (22%) Query: 139 RAAIAKTFYGGLGIGDD--DVFVSDGAKCDIS------RLQVMFGSNVTIAVQDPSYPAY 190 R I + GG + + D+F +G ++ R+ + + +A+ P + Y Sbjct: 148 RQYIVREMAGG-AVPPESVDLFAVEGGTAAMAYIFESLRISGLLKAGDKVAIGMPVFTPY 206 Query: 191 VDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGR-----TDIIFFCSPNNP 245 ++ + Q + P+NG+ + + + I F +P+NP Sbjct: 207 IEIPELA----------QYDLKEVPIHADPDNGWQYSDAELDKLKDPDVKIFFCVNPSNP 256 Query: 246 TGAAATREQLTQLVEFAKKN--GSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASF 303 + L ++ + +I+ D Y + D +S+F + + SF Sbjct: 257 PSVKMDQRSLDRVRAIVAEQRPDLLILTDDVYGTFA--DEFQSLFSVCPR--NTLLVYSF 312 Query: 304 SKYAGFTGVRLGWTVIPKKLLYSDGF-----------------------------PVAKD 334 SKY G TG RLG K ++ + D Sbjct: 313 SKYFGATGWRLGVIAAHKDNVFDHALSQLPESAKKALDHRYRSLLPDVRSLKFIDRLVAD 372 Query: 335 FNRIICTCFNGASNISQAGALA----CLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYD 390 + G S Q + L E +A + + + + Sbjct: 373 SRVVALNHTAGLSTPQQVQMVLFSLFALMDEA-DAYKQALKQLIRRREATLYRELGMPPL 431 Query: 391 VYGGKNAPYVWVHFPN-----------------QSSWDVFAEILEKTHVVTTPGSGFGPG 433 Y + N S+ D+ + ++T +V PG GFG Sbjct: 432 ENPNSVNYYTLIDLQNVTCRLYGEAFSQWAVQQSSTGDMLFRVADETGIVLLPGRGFGSD 491 Query: 434 GEGFVRVSAFG----HRENILEACRRFKQ 458 R S I A RR Sbjct: 492 RPSG-RASLANLNEYEYAAIGRALRRLAD 519 >4EMY-A nrPDB Length = 413 Score = 104 bits (259), Expect = 8e-23, Method: Composition-based stats. Identities = 70/408 (17%), Positives = 133/408 (32%), Gaps = 40/408 (9%) Query: 72 YLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGA 131 L +I + +A + KY VI+ +G + ++I + + Y Sbjct: 18 DLAFDINNKANAAIEKYGREAVINAALGTLLDDKGKIIALPSVYDRLDEMDRSHIASYAP 77 Query: 132 EQGAKPLRAAIAKTFYGGLGIGDD---DVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSY 187 +G K R + T +G + + G I S + + D + Sbjct: 78 IEGEKDYRKIVIDTLFG--PYKPEGYISAIATPGGTGAIRSAIFSYLDEGDPLICHDYYW 135 Query: 188 PAYVDSSVIMGQ---TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP-N 243 Y G+ T +F TD + Y E + R + SP N Sbjct: 136 APYRKICEEFGRNFKTFEFFTDDFAFNIDVYKEAIDEG-----IRDSDRIASLI-NSPGN 189 Query: 244 NPTGAAATREQLTQLVEFA------KKNGSIIVYDSAYAMYMSDDNPR----SIFEIPGA 293 NPTG + + E+ +++ F K ++ D AY + D + + F Sbjct: 190 NPTGYSLSDEEWDEVITFLKEKAEDKDKKITLIVDVAYLEFAGDGDQQRKFFEKFSNLPR 249 Query: 294 EEVAMETASFSKYAGFTGVRLGWTVI---PKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 + S SK G+R G V K+++ +A + A NI Sbjct: 250 NLFVVVAFSMSKSHTAYGLRSGAAVGISSSKEIIEEFEASLAHSARCNWSNGTHAAQNIL 309 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 410 A + + + K ++ + + + + P ++ Sbjct: 310 IELERAENKKIYEQELVDLRNMLKSRADVFVTAAKENKLTMIPYFGGFFTF--IPTDKAF 367 Query: 411 DVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFG-HRENILEACRRFK 457 D+ ++ EK ++ T P +G +RV+ G E I + +R Sbjct: 368 DIVKDL-EKENIFTIP------SAKG-IRVAICGVGEEKIPKLVQRLA 407 >5X03-B nrPDB Length = 365 Score = 101 bits (252), Expect = 5e-22, Method: Composition-based stats. Identities = 58/349 (16%), Positives = 111/349 (31%), Gaps = 50/349 (14%) Query: 129 YGAEQGAKPLRAAIAKT--FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPS 186 QG +RAAI + G+ + + + G + + L + A+++P Sbjct: 38 MSHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPG 97 Query: 187 YPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNN-- 244 Y + ++ G E G T + D + +P++ Sbjct: 98 Y-------------RRMYQLLKNAGKQVKTIMLDEKGMSIAEITRQQPD-VLVTTPSHQF 143 Query: 245 PTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAMETASF 303 P+G + QL+ +A + + + Y + D + + + + +F Sbjct: 144 PSGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTF 203 Query: 304 SKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGL 363 SK G+R+ + V+P +LL + K + TC + Q + E Sbjct: 204 SKSL-LPGLRISYMVLPPELLRA-----YKQRGYDLQTCSSLTQLTLQEFIESG---EYQ 254 Query: 364 EAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVV 423 + + K+ YKE +I + K A + +IL +H Sbjct: 255 KHIKKMKQHYKEKRERLITALEAEFSGEVTVKGANAGLHFVTEFDTRRTEQDIL--SHAA 312 Query: 424 TTPGSGFGPGGE----------------GFVRVSAFGHRENILEACRRF 456 FG GF R+ E+I E +R Sbjct: 313 GLQLEIFGMSRFNLKENKRQTGRPALIIGFARL----KEEDIQEGVQRL 357 >4N0B-A nrPDB Length = 479 Score = 101 bits (252), Expect = 5e-22, Method: Composition-based stats. Identities = 58/349 (16%), Positives = 111/349 (31%), Gaps = 50/349 (14%) Query: 129 YGAEQGAKPLRAAIAKT--FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPS 186 QG +RAAI + G+ + + + G + + L + A+++P Sbjct: 145 MSHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPG 204 Query: 187 YPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNN-- 244 Y + ++ G E G T + D + +P++ Sbjct: 205 Y-------------RRMYQLLKNAGKQVKTIMLDEKGMSIAEITRQQPD-VLVTTPSHQF 250 Query: 245 PTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAMETASF 303 P+G + QL+ +A + + + Y + D + + + + +F Sbjct: 251 PSGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTF 310 Query: 304 SKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGL 363 SK G+R+ + V+P +LL + K + TC + Q + E Sbjct: 311 SKSL-LPGLRISYMVLPPELLRA-----YKQRGYDLQTCSSLTQLTLQEFIESG---EYQ 361 Query: 364 EAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVV 423 + + K+ YKE +I + K A + +IL +H Sbjct: 362 KHIKKMKQHYKEKRERLITALEAEFSGEVTVKGANAGLHFVTEFDTRRTEQDIL--SHAA 419 Query: 424 TTPGSGFGPGGE----------------GFVRVSAFGHRENILEACRRF 456 FG GF R+ E+I E +R Sbjct: 420 GLQLEIFGMSRFNLKENKRQTGRPALIIGFARL----KEEDIQEGVQRL 464 >4WB0-B nrPDB Length = 414 Score = 101 bits (252), Expect = 6e-22, Method: Composition-based stats. Identities = 64/380 (16%), Positives = 116/380 (30%), Gaps = 36/380 (9%) Query: 59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMA 114 ++ K+Q P + A K P A ++ IG + P P + Sbjct: 9 MTTTERWQKIQGRAPDPIFELAKRAAAAKGPKANLV---IGAYRDEQGLPYPLRVVRKAE 65 Query: 115 KKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFV--SDGAKCDISRLQV 172 + +++ Y G +P K YG + +++ + +S Sbjct: 66 QLLLDMNL---NYEYLPISGYQPFIDEAVKMTYGDT-VELENLVAVQTLSGTGALSLGAK 121 Query: 173 MFG-----SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCT-PENGFFP 226 + I + DP++P + G D++ Y ++ G Sbjct: 122 LLTHVFDAEKTPIYLADPTWPNHYSIVKAAGWK-----DIRTYAYYDHKTLGLDFEGMKK 176 Query: 227 DLSTVGRTDIIFFC-SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR 285 D+ + +NPTG ++EQ ++ + +DSAY Y S Sbjct: 177 DILAAPDGSVFLLHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDT 236 Query: 286 SIFEIPGAEEVAMET---ASFSKYAGFTGVRLGW--TVIPKKLLYSDGFPVAKDFNRIIC 340 + +E SFSK G R G ++ K +D V R Sbjct: 237 DAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDSLIRAEY 296 Query: 341 TCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYV 400 TC + LA L E + I ++ ++ + P Sbjct: 297 TC-----PPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQ-TPGR 350 Query: 401 WVHFPNQSSWDVFAEILEKT 420 W H NQ F + ++ Sbjct: 351 WEHVINQIGMFSFLGLSKEQ 370 >5DJ3-A nrPDB Length = 376 Score = 101 bits (252), Expect = 6e-22, Method: Composition-based stats. Identities = 53/301 (17%), Positives = 118/301 (39%), Gaps = 17/301 (5%) Query: 169 RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDL 228 R+ + S+V++ + S A VD ++ T D+ + ++ + + DL Sbjct: 83 RVLSCYSSSVSMEILARSLSASVDRVALVHPTFDNIADLLRGNGLDLVPVEEDALHGADL 142 Query: 229 ST--VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRS 286 S + +F +PNNPTG E+L +L E ++G+++ D+++ + + + Sbjct: 143 SAELLSSVGCVFVTTPNNPTGRVLAEERLRRLAEQCAEHGTVLALDTSFRGFDAAAHYDH 202 Query: 287 IFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGA 346 + A + K ++ G V + + G PV K ++ I+ G Sbjct: 203 YAVLQEAGCRWVVIEDTGKLWPTLDLKAGLLVFSEDI----GLPVEKIYSDILL----GV 254 Query: 347 SNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPYV-WVHF 404 S + A + + F N +++ + G ++ V V F Sbjct: 255 SPLILALIREFSRDAADGGLADLHAFILHNRSVVRRALAGVEGVSFPDPESRSSVERVAF 314 Query: 405 PNQSSWDVFAEILEKTHVVTTPGSGFG----PGGEGFVRVSAFGHRENILEACRRFKQLY 460 ++ +V+ E+ ++ HV P F G+ VR++ E + ++ + + + Sbjct: 315 AGRTGTEVWEEL-QRHHVFALPCRQFHWAEPSDGDHMVRIALSRSTEPLEKSVQVLRTVL 373 Query: 461 K 461 + Sbjct: 374 E 374 >4W5K-A nrPDB Length = 396 Score = 99.5 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 46/325 (14%), Positives = 85/325 (26%), Gaps = 27/325 (8%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 P + ++L IG + + K+A T+ Y G Sbjct: 18 LGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA----TLGTNMDYAPVTGIASFVE 73 Query: 141 AIAKTFYGGL--GIGDDDVFV--SDGAKCDI----SRLQVMFGSNVTIAVQDPSYPAYVD 192 K +G + D + + G + L + I D YP + Sbjct: 74 EAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGYPNHES 133 Query: 193 SSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFF-CSPNNPTGAAAT 251 G + G L +I +NPTG T Sbjct: 134 IFAKAGM-----ELTPYSYYDPATKGLNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT 188 Query: 252 REQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIF---EIPGAEEVAMETASFSKYAG 308 + Q+ + K+ I D AY + + F + + SFS G Sbjct: 189 HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSANFG 248 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGL----- 363 G R G + + + +I ++ + L L Sbjct: 249 LYGHRCG-ALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWK 307 Query: 364 EAMHKVIGFYKENTNIIIDTFTSLG 388 + + ++ E ++ + G Sbjct: 308 KELKQMSSRIAEVRKRLVSELKACG 332 >3MEB-A nrPDB Length = 448 Score = 99.5 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 44/336 (13%), Positives = 94/336 (27%), Gaps = 30/336 (8%) Query: 90 DAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKT 145 + + ++LG+G ++ +P A+ + Y G A A+ Sbjct: 48 NPKKVNLGVGAYRDESGKPWILPAVKE-AEAIISSDLSKYNKEYPPVAGFPLFLEA-AQF 105 Query: 146 FYGGLGIGDDD--------VFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIM 197 G G+ ++ + ++P + + Sbjct: 106 LMFGKDSKAAQEGRIASCQSLSGTGSLHIGFEFLHLWMPKAEFYMPSTTWPNHYGIYDKV 165 Query: 198 GQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI-IFFCSPNNPTGAAATREQLT 256 + Y + + D+ + I +F +NP+G T Q Sbjct: 166 FNKLKVPYKEYTYLRKDGELEIDFSNTKKDIQSAPEKSIFLFHACAHNPSGIDFTEAQWK 225 Query: 257 QLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIP---GAEEVAMETASFSKYAGFTGVR 313 +L+ K+ I +DSAY + + F + A + SFSK G G R Sbjct: 226 ELLPIMKEKKHIAFFDSAYQGFATGSFEADAFAVRMFVDAGVEVLVAQSFSKNFGLYGER 285 Query: 314 LGWTVI-----------PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPE- 361 +G + K L + + + + I Q + Sbjct: 286 IGCLHVVHAGVEGSVEKNKALSAAMVSGMTLQIRKTWSMSAIHGAYIVQVIVHDKRLLQM 345 Query: 362 GLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNA 397 + + ++ +++ + G K Sbjct: 346 FYDNVKEMSARIHRMRSLLHASLAKRKTPGPGSKGT 381 >4WD2-A nrPDB Length = 408 Score = 99.5 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 50/345 (14%), Positives = 95/345 (27%), Gaps = 28/345 (8%) Query: 83 AHLLKYPDAQVISLGIG---DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLR 139 + K P Q ++L IG D IP + A+ + L G Y G R Sbjct: 26 ENFQKDPRDQKVNLSIGIYFDAEGRIP--VMGAVREAETALQRDSGPKPYLPMVGLAAYR 83 Query: 140 AAIAK--TFYGGLGIGDDDV--FVSDGAKCDISRLQVMFG---SNVTIAVQDPSYPAYVD 192 A+ + + G + + + + DPS+ + Sbjct: 84 DAVQSLVFGADHPARAAGRIATLQTLGGSGALKVGADFLKRYFPDSQVWLSDPSW---EN 140 Query: 193 SSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATR 252 I + G Y D ++ C +NPTG Sbjct: 141 HRFIFERAGFTVNTYPYYDEATGGLKFDAMLAAIDALPARSIVLLHACC-HNPTGVDLDE 199 Query: 253 EQLTQLVEFAKKNGSIIVYDSAYAMYMS--DDNPRSIFEIPGAEEVAMETASFSKYAGFT 310 Q +L++ + + D AY + + D + ++ E+ + SFSK Sbjct: 200 GQWEKLIDVIEARELLPFVDMAYQGFGAGLDADAFAVRELARRGVPTLVANSFSKNFSLY 259 Query: 311 GVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALA-----CLTPEGLEA 365 G R+G + + + V + + ++ A L + E Sbjct: 260 GERVGGLSVVCED-AAAAERVLGQLAGAVRSNYSNPQTYGAKVVAAVLGTPALRKQWEEE 318 Query: 366 MHKVIGFYKENTNIIIDTFTSL----GYDVYGGKNAPYVWVHFPN 406 + + I D Y + + + Sbjct: 319 LSAMCRRIARMRQSIHDGLRDHVSGEALTRYVKQRGMFTYTGLTE 363 >2X5F-A nrPDB Length = 430 Score = 99.1 bits (245), Expect = 4e-21, Method: Composition-based stats. Identities = 60/416 (14%), Positives = 136/416 (32%), Gaps = 38/416 (9%) Query: 65 MSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIE 124 +S L +P+ +SA + + IG T ++ S++ ++L+ E Sbjct: 25 LSDLGQNMFYPKGILSQSAEA----KSTTYNATIGMATNKDGKMFASSLDAMFNDLTPDE 80 Query: 125 GYSGYGAEQGAKPLRAAIAKT-FYGGLGIGDDD---VFVSDGAKCDISRLQVMF-GSNVT 179 + Y QG + LR + + D+ V++ +S + +F + T Sbjct: 81 IFP-YAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIVTNALTHGLSLVGDLFVNQDDT 139 Query: 180 IAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFF 239 I + + ++ Y V + G + + + I+ Sbjct: 140 ILLPEHNWGNYK--LVFNTRNGANLQTYPIFDKDGHYTTDSLVEALQSYNK--DKVIMIL 195 Query: 240 CSPNNPTGAAATREQLTQLVEFAKK-----NGSIIVYDSAYAMYMSDDN-----PRSIFE 289 PNNPTG T +++T +VE K I V D AY +D ++ Sbjct: 196 NYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFYEDVYTQSLFTALTN 255 Query: 290 IPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNI 349 + + + +K G R+G+ + AK I +G Sbjct: 256 LHSNAILPIRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPL-P 314 Query: 350 SQAGALACLT--PEGLEAMHKVIGFYKENTNIIIDTFTS----LGYDVYGGKNAPYVWVH 403 +Q+ L + + + + I KE + + + + Y + ++ + Sbjct: 315 TQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIK 374 Query: 404 FPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFG-HRENILEACRRFKQ 458 + + +++K + + +R++ +++I + Sbjct: 375 VHDVDPEALRKHLIDKYSIGVIALNATD------IRIAFSCVEKDDIPHVFDSIAK 424 >4H51-A nrPDB Length = 420 Score = 99.1 bits (245), Expect = 4e-21, Method: Composition-based stats. Identities = 61/358 (17%), Positives = 109/358 (30%), Gaps = 30/358 (8%) Query: 75 PEIARRRSAHLLKYPDAQVISLGIG----DTTEPIPEVITSAMAKKAHELSTIEGYSGYG 130 P++ + + +L IG + P P + + +++ Y Sbjct: 29 PDVIFDLAKRAAAAKGPKA-NLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDY---EYL 84 Query: 131 AEQGAKPLRAAIAKTFYGGLGIGDDDVFV------SDGAKCDISRLQVMFGSNVT-IAVQ 183 G +P K Y G + +++ + L +F + T I + Sbjct: 85 PISGYQPFIDEAVKIIY-GNTVELENLVAVQTLSGTGAVSLGAKLLTRVFDAETTPIYLS 143 Query: 184 DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPN 243 DP++P + G Y + + + E L+ + I + Sbjct: 144 DPTWPNHYGVVKAAGWKNICT---YAYYDPKTVSLNFEGMKKDILAAPDGSVFILHQCAH 200 Query: 244 NPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET--- 300 NPTG ++EQ ++ + +DSAY Y S + +E Sbjct: 201 NPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLA 260 Query: 301 ASFSKYAGFTGVRLGW--TVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACL 358 SFSK G R G ++ K +D V R TC + LA L Sbjct: 261 QSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTC-----PPAHGARLAHL 315 Query: 359 TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEI 416 E + I ++ ++ + P W H NQ F + Sbjct: 316 ILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQ-TPGSWEHVINQIGMFSFLGL 372 >3F6T-A nrPDB Length = 533 Score = 98.7 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 67/375 (17%), Positives = 115/375 (30%), Gaps = 82/375 (21%) Query: 156 DVFVSDGAKCDI------SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 D+F ++G I + IA+ +P + Y+ + D+ Sbjct: 166 DLFPTEGGTAAIVYAFHSLAENHLLKKGDKIAINEPIFTPYLRIPEL-KDYELVEVDLHS 224 Query: 210 YGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNG-SI 268 Y ++ E D + +P NPT L + + +KN + Sbjct: 225 YEKNDWEIEPNEIEKLKD----PSIKALIVVNPTNPTSKEFDTNALNAIKQAVEKNPKLM 280 Query: 269 IVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD- 327 I+ D Y ++ N +SI+ + M S+SK G TG RLG + +K ++ D Sbjct: 281 IISDEVYGAFV--PNFKSIYSVVPY--NTMLVYSYSKLFGCTGWRLGVIALNEKNVFDDN 336 Query: 328 ----------------------------GFPVAKDFNRIICTCFNGASNISQAG------ 353 + D I G S Q Sbjct: 337 IAHLDKVELRQLHKRYSSVVLDPDKMKFIDRLCADSRSIGLYHTAGLSTPQQIMEALFSM 396 Query: 354 -----------------ALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGY-----DV 391 L E + +H + K+ T+ ++ + + Sbjct: 397 THLLTSTNGGSDDPYIDIARKLVSERYDQLHDAMQAPKDETDTNTHYYSLIDIYRLAEKI 456 Query: 392 YGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFG----HRE 447 YG + Y+ +F D ++ EK VV G GFG G +RVS Sbjct: 457 YGKEFRDYLTNNFEQV---DFLLKLAEKNGVVLVDGVGFGAK-PGELRVSQANLPTEDYA 512 Query: 448 NI-LEACRRFKQLYK 461 I + K+ Y+ Sbjct: 513 LIGKQVLELLKEYYE 527 >4RKC-A nrPDB Length = 398 Score = 94.5 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 54/352 (15%), Positives = 104/352 (29%), Gaps = 36/352 (10%) Query: 90 DAQVISLGIG---DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTF 146 + ++LGIG D + +P + + ++ Y G R + Sbjct: 25 NPDKVNLGIGIYYDESGVMP--VLDCVKIAEQRIADPISPRPYLPMAGLPGHRKGCQELL 82 Query: 147 YGGLGIGDDD----VFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQ 202 +G D + G + ++ F P YV Sbjct: 83 FGKDAPVLKDGLVATIATIGGSGAL-KVGAEFIHEWF-----PQSKCYVSDPTWGNHIAI 136 Query: 203 FNTDVQKYGNIEYMRCTPENGFFPDLSTVGRT---DIIFFCSP--NNPTGAAATREQLTQ 257 F + G Y F ++ T D + P +NPTG TREQ Sbjct: 137 FEGCDIEVGKYPYYDTATGGIKFDEMIAFFETLNKDDVLLLHPCCHNPTGVDLTREQWDT 196 Query: 258 LVEFAKKNGSIIVYDSAYAMYMS--DDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 ++ ++ I D AY + D + +I + + SFSK G R+G Sbjct: 197 VLNVIQERELIPFMDIAYQGFGEDMDSDAYAIRKAVDMGLPLFVSNSFSKNLSLYGERVG 256 Query: 316 --WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASN-----ISQAGALACLTPEGLEAMHK 368 V P + V N + ++ + + A L + + ++ Sbjct: 257 GLSVVCP---TVDETERVFGQLNSTVRRIYSSPPSHGGRVVDIVMNDAALHEQWVGEVYA 313 Query: 369 VIGFYKENTNIIIDTFTSL----GYDVYGGKNAPYVWVHFPNQSSWDVFAEI 416 + K + + +D +N + + + + +E Sbjct: 314 MRDRIKSMRTKLKSVLEAKISGRNFDYLTAQNGMFSFTGLTPEQVERLQSEF 365 >4WBT-A nrPDB Length = 376 Score = 93.3 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 57/373 (15%), Positives = 119/373 (31%), Gaps = 44/373 (11%) Query: 82 SAHLLKYPDAQVISLGIG--DTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLR 139 L+ + I+ IG ++ + A+ + A + Y + L+ Sbjct: 25 GPEALERQHGRKIAARIGANESGFGPAPSVLLAIRQAAGDTW------KYADPE-NHDLK 77 Query: 140 AAIAKTFYGGLGIGDDDVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMG 198 A+A+ LG ++ + +G + ++++ + + YP + G Sbjct: 78 QALAR----HLGTSPANIAIGEGIDGLLGQIVRLVVEAGAPVVTSLGGYPTFNYHVAGHG 133 Query: 199 QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQL 258 ++E + P +++ +P+NP G+ E++ Sbjct: 134 GRLVTVPYADDREDLEGLLAAVGRENAP---------LVYLANPDNPMGSWWPAERVVAF 184 Query: 259 VEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTV 318 + + +++V D AY D I E + + +FSK G G R+G+T+ Sbjct: 185 AQALPET-TLLVLDEAYCETAPRDALPPI-ESLIDKPNVIRARTFSKAYGLAGARIGYTL 242 Query: 319 IPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTN 378 A+ F++I G S I A A + + +V + Sbjct: 243 --------STPGTAQAFDKIRNHF--GMSRI--GVAAAIAALADQDYLKEVTLKIANSRQ 290 Query: 379 IIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVF--AEILEKTHVVT-TPGSGFGPGGE 435 I G +V V +S+ ++ + PG Sbjct: 291 RIGRIAADSGL-APLPSATNFVAVDCGKDASYARAIVDRLMSDHGIFIRMPGVA---PLN 346 Query: 436 GFVRVSAFGHREN 448 +R+S E Sbjct: 347 RCIRISTAPDAEM 359 >4EFF-A nrPDB Length = 420 Score = 84.4 bits (207), Expect = 8e-17, Method: Composition-based stats. Identities = 54/362 (14%), Positives = 109/362 (30%), Gaps = 44/362 (12%) Query: 91 AQVISLGIGDTTEPIPE-VITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGG 149 ++LG+G T + + A+ GY G A++ K Sbjct: 49 PTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDASVQKLL--- 105 Query: 150 LGIGDDDVFVSDG---------AKCDI---SRLQVMFGSNVTIAVQDPSYPAYVDSSVIM 197 +GDD ++ G + + +A+ DPS+ + + Sbjct: 106 --LGDDSPLIAAGRVVTAQALGGTGALKIGADFLRTLNPKAKVAISDPSWENHRALFDMA 163 Query: 198 GQTGQFNTDVQKYGNIEYM--RCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQL 255 G N NG+ P T ++ +NPTG Q Sbjct: 164 GFEVVAYPYYDAKTNGVNFDGMLAALNGYEPG------TIVVLHACCHNPTGVDLNDAQW 217 Query: 256 TQLVEFAKKNGSIIVYDSAYAMYMS--DDNPRSIFEIPGAEEVAMETASFSKYAGFTGVR 313 Q+VE K + D AY + + + ++ A ++SFSK G R Sbjct: 218 AQVVEVVKARRLVPFLDIAYQGFGESIEADAAAVRLFAAANLNVFVSSSFSKSFSLYGER 277 Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALAC------LTPEGLEAMH 367 +G I + V R+I T ++ +A L ++ + Sbjct: 278 VGALSIITDS-KDEAARVLSQLKRVIRTNYSNPPTHG-GAIVAAVLASPELRASWVQELG 335 Query: 368 KVIGFYKENTNIIIDTFTSLG----YDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVV 423 ++ + N +++ + G + + + + + + E+ + Sbjct: 336 EMRDRIRAMRNGLVERLKAAGIERDFSFINAQRGMFSYSGL----TSAQVDRLREEFGIY 391 Query: 424 TT 425 Sbjct: 392 AV 393 >6C3C-A nrPDB Length = 413 Score = 79.4 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 56/346 (16%), Positives = 109/346 (31%), Gaps = 40/346 (11%) Query: 129 YGAEQGAKP-----LRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFG-SNVTIAV 182 Y AE+G + A + + + +S A + + + + Sbjct: 75 YEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTL 134 Query: 183 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 +P + D M + D + +++ + +P+L RTD +F P Sbjct: 135 IEPCFDNLYDVLANM-DVPLYPIDESVFYDVDRI--------YPELERRVRTDALFLVDP 185 Query: 243 NNPTGAAA---TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEE---- 295 NNPTG + R+ ++V F K + +++ D +A + + + F++ E Sbjct: 186 NNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGV 245 Query: 296 VAMETASFSKYAGFTGVRLGWTVIPKK-LLYSDGFPVAKDFNRIICTCFNGASNISQAGA 354 + K W V K L + + + + + S Sbjct: 246 RYLAIEDTGKT---------WPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNML 296 Query: 355 LACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYV-W--VHFPNQSSWD 411 + + + V N T + V W V P ++ D Sbjct: 297 TQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATD 356 Query: 412 VFAEILEKTHVVTTPGSGF----GPGGEGFVRVSAFGHRENILEAC 453 V +L V PG F G+ +VR++ E +A Sbjct: 357 V-HRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAM 401 >3K7Y-A nrPDB Length = 405 Score = 72.9 bits (177), Expect = 3e-13, Method: Composition-based stats. Identities = 49/268 (18%), Positives = 79/268 (29%), Gaps = 26/268 (9%) Query: 65 MSKLQAGYLFPEIARRRSAHLLKYPD--AQVISLGIGDTTEPI-PEVITSAMAKKAHELS 121 M KL + E+ D + I+L IG I ++ ++ Sbjct: 1 MDKLLSSLENIEVDNILKTAREFKEDTCEEKINLSIGVCCNDDGDLHIFDSVLNADKLVT 60 Query: 122 TIEGYSGYGAEQGAK---PLRAAIAKTFYGGLGIGDDDVFVSD---GAKCDISRLQVMFG 175 Y G + L + F +D + G I L Sbjct: 61 ENYKEKPYLLGNGTEDFSTLTQNLI--FGNNSKYIEDKKICTIQCIGGTGAIFVLLEFLK 118 Query: 176 --SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPEN--GFFPDLSTV 231 + T+ V +P Y +V+ G KY N N F DL + Sbjct: 119 MLNVETLYVTNPPYINHVNMIESRGFN-------LKYINFFDYNLIDINYDLFLNDLRNI 171 Query: 232 GRTDIIFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 290 + S NP + +++E +I++D AY + + + I Sbjct: 172 PNGSSVILQISCYNPCSVNIEEKYFDEIIEIVLHKKHVIIFDIAYQGFGHTNLEEDVLLI 231 Query: 291 PGAEEVAM---ETASFSKYAGFTGVRLG 315 EE + SFSK G R G Sbjct: 232 RKFEEKNIAFSVCQSFSKNMSLYGERAG 259 >5IWQ-A nrPDB Length = 434 Score = 71.4 bits (173), Expect = 8e-13, Method: Composition-based stats. Identities = 64/423 (15%), Positives = 132/423 (31%), Gaps = 69/423 (16%) Query: 73 LFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMA---KKAHELSTIEGYSGY 129 LF E +R+ LK + ++ L G + + +A K + + Y Sbjct: 16 LFHEDIKRKF-DELKSKNLKL-DLTRGKPSSEQLDFADELLALPGKGDFKAADGTDVRNY 73 Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDIS----RLQVMFGSNVTI----- 180 G G +R A LG+ + V D + +I +FG+N ++ Sbjct: 74 GGLDGIVDIRQIWA----DLLGVPVEQVLAGDASSLNIMFDVISWSYIFGNNDSVQPWSK 129 Query: 181 ------AVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRT 234 P Y + + G + ++ P+ +L + Sbjct: 130 EETVKWICPVPGYDRHFSITERFG---------FEMISVPMNEDGPDMDAVEELVKNPQV 180 Query: 235 DIIFFC-SPNNPTGAAATREQLTQLVEF-AKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG 292 ++ +NPTG T + +L +V+D+AYA++ D + +I G Sbjct: 181 KGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVIDIVG 240 Query: 293 AEE------VAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGA 346 E S SK G + + + + K + G Sbjct: 241 LGEAAGNPNRFWAFTSTSKI-TLAGAGVSFFLTSAE--------NRKWYTGHAGIRGIGP 291 Query: 347 SNISQAGALACLTPEGLEAMHKVIG----FYKENTNIIID----TFTSLGY-DVYGGKNA 397 + ++Q E + V+ N +++ G Sbjct: 292 NKVNQLA--HARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVAQWTVPAGG 349 Query: 398 PYVWVHFPNQSSWDVFAEILEKTHVVTT-PGSGF----GPGGEGFVRVS-AFGHRENILE 451 ++ + ++ V AE+ ++ + T GS + P + +R++ + E + Sbjct: 350 YFISLDVVPGTASRV-AELAKEAGIALTGAGSSYPLRQDPENKN-LRLAPSLPPVEELEV 407 Query: 452 ACR 454 A Sbjct: 408 AMD 410 >3BWN-A nrPDB Length = 391 Score = 69.4 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 63/356 (17%), Positives = 110/356 (30%), Gaps = 75/356 (21%) Query: 136 KPLRAAIAKTFYGGLGIGDDD---VFVSDGAKC----DISRLQVMFGS-NVTIAVQDPSY 187 L AI K +G +G + + V G+ + L + S V++ P Y Sbjct: 71 PELEDAI-KDLHGVVGNAATEDRYIVVGTGSTQLCQAAVHALSSLARSQPVSVVAAAPFY 129 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTG 247 YV+ + + M + + D I SPNNP G Sbjct: 130 STYVEETTYVRS---------------GMYKWEGDAWGFD---KKGPYIELVTSPNNPDG 171 Query: 248 AAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYA 307 +V + + +++D AY R ++ + +FSK Sbjct: 172 TI-----RETVVNRPDDDEAKVIHDFAYYWPHYTPITR-------RQDHDIMLFTFSKIT 219 Query: 308 GFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT--PEGLEA 365 G G R+GW ++ K VAK I G S SQ L E ++ Sbjct: 220 GHAGSRIGWALVKDK-------EVAKKMVEYIIVNSIGVSKESQVRTAKILNVLKETCKS 272 Query: 366 MHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAP----------------------YVWVH 403 + F+K ++ + + L +V +A + W+ Sbjct: 273 ESESENFFKYGREMMKNRWEKLR-EVVKESDAFTLPKYPEAFCNYFGKSLESYPAFAWLG 331 Query: 404 FPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459 ++ L + V++ G G + VRVS + R + Sbjct: 332 TKEETDLVSE---LRRHKVMSRAGERCG-SDKKHVRVSMLSREDVFNVFLERLANM 383 >2HOR-A nrPDB Length = 427 Score = 69.0 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 56/354 (15%), Positives = 102/354 (28%), Gaps = 63/354 (17%) Query: 137 PLRAAIAKTFY--GGLGIGDDDVFVSDGAKCDISRLQVMFGSNVT---------IAVQDP 185 L I + G D + G I L + N+T + P Sbjct: 104 ELEKTIKELHEVVGNAAAKDRYIVFGVGVTQLIHGLVISLSPNMTATPDAPESKVVAHAP 163 Query: 186 SYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNP 245 YP + + + + G V Y+ + + SPNNP Sbjct: 164 FYPVFREQTKYFDKKG----YVWAGNAANYVNVSNPEQYIE-----------MVTSPNNP 208 Query: 246 TGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSK 305 G L+ A G +YD Y + + + SK Sbjct: 209 EG----------LLRHAVIKGCKSIYDMVYYWPHYTPIKYKA-------DEDILLFTMSK 251 Query: 306 YAGFTGVRLGWTVIPKKLLY----------SDGFPVAKDFNRIICTCFNGASNISQAGAL 355 + G +G R GW +I + +Y ++G P + A +Q G + Sbjct: 252 FTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLRSLKVLKEVVAMVKTQKGTM 311 Query: 356 ACLTPEGLEAMHK----VIGFYKENTNIIIDTFTSLG----YDVYGGKNAPYVWVHFPNQ 407 L G + + + + ++ + + Y WV + Sbjct: 312 RDLNTFGFKKLRERWVNITALLDQSDRFSYQELPQSEYCNYFRRMRPPSPSYAWVKCEWE 371 Query: 408 SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461 D + + + T G GF +VR+S +++ + K + K Sbjct: 372 EDKDCYQTF-QNGRINTQNGVGF-EASSRYVRLSLIKTQDDFDQLMYYLKDMVK 423 >4LW2-A nrPDB Length = 404 Score = 62.5 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 63/392 (16%), Positives = 114/392 (29%), Gaps = 61/392 (15%) Query: 106 PEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFV-SDGAK 164 PE + A + + S + Q A + L DD V + G Sbjct: 35 PEAVVEATQQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTT 94 Query: 165 CDISRLQVM-----FGSNVTIAVQ-DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRC 218 I+ + I V + V ++ QTG + Sbjct: 95 ESINMVAQCYARPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQR----- 149 Query: 219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMY 278 P+ P+L R+ I+ +N TG L + + FA G +++ D A Sbjct: 150 LPDVDLLPEL-ITPRSRILALGQMSNVTGGCPD---LARAITFAHSAGMVVMVDGA---- 201 Query: 279 MSDDNPRSIFEIPGAEEVAMETASFS--KYAGFTGVRLGWTVIPKKLLYS---------- 326 ++ + ++ +FS K G TG +G +LL + Sbjct: 202 --QGAVHFPADVQQLD---IDFYAFSGHKLYGPTG--IGVLYGKSELLEAMSPWLGGGKM 254 Query: 327 ------DGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNII 380 DGF ++ N A I + AL L + + Sbjct: 255 VHEVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEWLADYDINQAESWSRSL---ATLA 311 Query: 381 IDTFTSL-GYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSG-----FGPGG 434 D G+ + +++ + F D+ +L + + G G Sbjct: 312 EDALAKRPGFRSFRCQDSSLLAFDFAGVHHSDMVT-LLAEYGIALRAGQHCAQPLLAELG 370 Query: 435 -EGFVRVSAFG-----HRENILEACRRFKQLY 460 G +R S + ++ A R +L Sbjct: 371 VTGTLRASFAPYNTKSDVDALVNAVDRALELL 402 >1M6S-A nrPDB Length = 347 Score = 62.1 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 62/360 (17%), Positives = 116/360 (32%), Gaps = 40/360 (11%) Query: 110 TSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISR 169 T M K + G YG + L A+TF + FV G + Sbjct: 17 TEEMRKAMAQAEV--GDDVYGEDPTINELERLAAETFGKEAAL-----FVPSGTMGNQVS 69 Query: 170 LQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLS 229 + + ++ S+ + + + +G V P Sbjct: 70 IMAHTQRGDEVILEADSHIFWYEVGAMAVLSGVMPHPVPGKNGAMD-PDDVRKAIRPRNI 128 Query: 230 TVGRTDIIFFCSPNNPTG-AAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIF 288 RT +I + +N +G E + ++ AK++G + D A S + + Sbjct: 129 HFPRTSLIAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGVPVK 188 Query: 289 EIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASN 348 E G + M SK +G V+ D A+ +++ A Sbjct: 189 EYAGYADSVMFC--LSKGLCAP---VGSVVVGD----RDFIERARKARKMLGGGMRQAGV 239 Query: 349 ISQAGALACLTPEGLEAMHKVIGFYK---ENTNIIIDTFTSLGYDVYG--GKNAPYVWVH 403 ++ AG +A + K++ K EN + +GY V K + Sbjct: 240 LAAAGIIA---------LTKMVDRLKEDHENARFLALKLKEIGYSVNPEDVKTNMVILRT 290 Query: 404 FPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAF--GHRENILEACRRFKQLYK 461 + + F E L + V+ S + +R+ R +I EA F++L++ Sbjct: 291 DNLKVNAHGFIEALRNSGVLANAVS------DTEIRLVTHKDVSRNDIEEALNIFEKLFR 344 >2X8U-A nrPDB Length = 412 Score = 56.3 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 44/263 (16%), Positives = 90/263 (34%), Gaps = 30/263 (11%) Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPA 189 G QG K A+ + + + + S G + ++ + + G I + S Sbjct: 86 GTYQGHKACEDALKEFYG-----TEHAIVFSTGYQANLGMISTLAGKGDYIILDADS--- 137 Query: 190 YVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAA 249 + I + ++ ++ + G P ++ + G Sbjct: 138 ---HASIYDGCWLGDAEIVRFRHNSVEDLDKRLGRLP----AEAGKLVVLEGVYSMMGDI 190 Query: 250 ATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE-EVAMETASFSKYAG 308 A L ++V +KK+G++I+ D A+ M ++ R +FE G E +V +FSK G Sbjct: 191 AP---LQEMVAVSKKHGAMILVDEAHGMGFFGEHGRGVFEEAGVEADVDFVVGTFSKSVG 247 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHK 368 G G+ V F V + R + ++ A + Sbjct: 248 TVG---GFCVSNHPK-----FEVLRLVCRPYVFTASLPPSVVATAATSIRKLMHAGDKRA 299 Query: 369 VIGFYKENTNIIIDTFTSLGYDV 391 + +N+ + +GY + Sbjct: 300 HLW---KNSRRLHQGLRDMGYKL 319 >4W91-A nrPDB Length = 422 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 57/443 (12%), Positives = 127/443 (28%), Gaps = 82/443 (18%) Query: 66 SKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAM-AKKAHELSTIE 124 + L Y I R + ++ L G + + P+ + A+ A+E + + Sbjct: 13 NPLTMAYDVEAIRRDFPILSRQVHGKTLVYLDNGASAQ-KPQSVIDAVTHAYANEYANVH 71 Query: 125 GYSGY---GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL-----QVMFGS 176 + A + R + + G D++ + A I+ + G Sbjct: 72 RGLHFLSNAATDAYEKSRETVRRFLNAG---SVDEIVFTKNATEAINTVAYGYGMPFIGE 128 Query: 177 NVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST---VGR 233 I + S I+ ++ + + F + R Sbjct: 129 GDEILL-----SIMEHHSNIV---PWHFIRERQGAKLVFTPVDDNGVFHIEEFEKRLSER 180 Query: 234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 T ++ +N G + ++VE A G ++ D S ++ Sbjct: 181 TKLVAITHMSNTLGTVVP---IKKIVELAHARGIPVLVD------GSQGAVHLPVDVQDL 231 Query: 294 EEVAMETASFSKYAGFTGVRLGWTVIPKKLLYS-DGFPVAKDFNRIIC---TCFNGA--- 346 + K G +G +G ++L F + + +N Sbjct: 232 GC-DWYVFTGHKVYGPSG--IGVLYGRAQMLEKMRPFQGGGEMIEEVTEENVTYNHPPHR 288 Query: 347 -----SNISQAGAL-ACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYV 400 I QA L A L H ++ + + + + N+ + Sbjct: 289 FEAGTPPIVQAIGLGAALEYMEKIGRHAILAHEADLRDYAHERLGRI--------NSLRI 340 Query: 401 WVHFPNQSSWDVFAE----------ILEKTHVVTTPGS--------GFGPGGEGFVRVSA 442 + + P++ + FA ++++ V G+ FG R S Sbjct: 341 FGNAPDKGAIISFALEGIHAHDVSMVIDRAGVAVRAGTHCAQPLLKRFGV--TSTCRASF 398 Query: 443 F-----GHRENILEACRRFKQLY 460 + + EA + ++ + Sbjct: 399 ALYNTRAEVDALAEALEKARKFF 421 >5C6U-A nrPDB Length = 435 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 53/432 (12%), Positives = 121/432 (28%), Gaps = 62/432 (14%) Query: 65 MSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIE 124 L L AR + + + L G + ++ ++ + E Sbjct: 2 FDSLSPQELAALHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPGDDYRDPE 61 Query: 125 GY--SGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFG------- 175 G YG + G LRA A+ LGI ++ + + ++ V F Sbjct: 62 GTDTRNYGGQHGLPGLRAIFAEL----LGIAVPNLIAGNNSSLELMHDIVAFSMLYGGVD 117 Query: 176 ---------SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFP 226 + P Y + + MG +Q +++ + Sbjct: 118 SPRPWIQEQDGIKFLCPVPGYDRHFAITETMGIEMIPIPMLQDGPDVDLIEEL------- 170 Query: 227 DLSTVGRTDIIF-FCSPNNPTGAAATREQLTQLVEF-AKKNGSIIVYDSAYAMYMSDDNP 284 ++ ++ NP+G + E + +LV+ + +D+AYA++ + Sbjct: 171 -VAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMRTAAPDFRLFWDNAYAVHTLTLDF 229 Query: 285 RSIFEIP------GAEEVAMETASFSK-YAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNR 337 ++ G AS SK + + + Sbjct: 230 PRQVDVLGLAAKAGNPNRPYVFASTSKITFA----------GGGVSFFGGSLGNIAWYLQ 279 Query: 338 IICTCFNGASNISQAGALACLTPEGLEAMHKVI--GFYKENTNIIIDTF-----TSLGYD 390 G ++Q L +H + ++ + S Sbjct: 280 YAGKKSIGPDKVNQLRHLRFFGDADGVRLHMLRHQQILAPKFALVAEVLDQRLSESKIAS 339 Query: 391 VYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTT-PGSGF---GPGGEGFVRVS-AFGH 445 K ++ + ++ A + + + T G+ F + +R++ +F Sbjct: 340 WTEPKGGYFISLDVLPGTARRTVA-LAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPS 398 Query: 446 RENILEACRRFK 457 ++ A Sbjct: 399 VPDLRNAVDGLA 410 >4BMK-A nrPDB Length = 442 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 56/350 (16%), Positives = 110/350 (31%), Gaps = 43/350 (12%) Query: 105 IPEVI---TSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSD 161 P+VI A+ K + +G + A+ + + S Sbjct: 102 DPDVIAAGKEALEKFGSGTNGSRMLNG--TFHDHMEVEQALRDFYGTTGA-----IVFST 154 Query: 162 GAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPE 221 G ++ + + G + + S + I Q N ++ ++ + Sbjct: 155 GYMANLGIISTLAGKGEYVILDADS------HASIYDGCQQGNAEIVRFRHNSVEDLDKR 208 Query: 222 NGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSD 281 G P ++ + G A L ++V AKK+G++++ D A++M Sbjct: 209 LGRLP----KEPAKLVVLEGVYSMLGDIAP---LKEMVAVAKKHGAMVLVDEAHSMGFFG 261 Query: 282 DNPRSIFEIPGAE-EVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIIC 340 N R ++E G E ++ +FS G G G+ V P + Sbjct: 262 PNGRGVYEAQGLEGQIDFVVGTFSASVGTVG---GFVVSN--------HPKFEAVRLACR 310 Query: 341 TCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDV-YGGKNAPY 399 AS A A + L H+ N + ++G+ + ++ Sbjct: 311 PYIFTASLPPSVVATATTSIRKLMTAHEKRERLWSNARALHGGLKAMGFRLGTETCDSAI 370 Query: 400 VWVHFPNQSSWDVFAEILEKTHVVTT----PGSGFGPGGEGFVRVSAFGH 445 V V +Q + + L + P + P G +R S Sbjct: 371 VAVMLEDQEQAAMMWQALLDGGLYVNMARPPAT---PAGTFLLRCSICAE 417 >6CJB-A nrPDB Length = 391 Score = 51.7 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 40/223 (17%), Positives = 72/223 (32%), Gaps = 31/223 (13%) Query: 90 DAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAA----IAKT 145 D + I G + + V+T A ++ + GY + P R A IA Sbjct: 15 DTRAIHAGQ-EPCKSTGAVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIASL 73 Query: 146 FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNT 205 G G + G I+ + + GS + D Y G F+ Sbjct: 74 ESGQKGFA-----FASG-MAAINTVIDLLGSGDHVVAMDDLY---------GGTFRLFDK 118 Query: 206 DVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKN 265 + N+ + + + +T +++ +P+NP L ++ AKK Sbjct: 119 VKTRTSNLSFSFIDMSVPENIEAAITPKTKLLWLETPSNP---MLKLANLRKIAAIAKKY 175 Query: 266 GSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 I V D+ +A + P + S +KY Sbjct: 176 NLITVADNTFA--------TPWIQRPLELGFDIVLHSATKYLN 210 >1FC4-A nrPDB Length = 401 Score = 51.3 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 53/334 (15%), Positives = 109/334 (32%), Gaps = 41/334 (12%) Query: 137 PLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVI 196 L +A I F ++G + + G+ I ++ + I Sbjct: 94 ELEQKLAAFLGMEDAILYSSCFDANGG-----LFETLLGAEDAIISDA------LNHASI 142 Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATRE--- 253 + +Y N + + G ++ T + + Sbjct: 143 IDGVRLCKAKRYRYANNDMQEL---EARLKEAREAGARHVLIA------TDGVFSMDGVI 193 Query: 254 -QLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTG 311 L + + A K ++++ D ++A ++ ++ S V + T + K G G Sbjct: 194 ANLKGVCDLADKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGRVDIITGTLGKALG--G 251 Query: 312 VRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIG 371 G+T K+++ + +R + A I A E +EA ++ Sbjct: 252 ASGGYTAARKEVVE-----WLRQRSRPYLFSNSLAPAIVAASIKV---LEMVEAGSELRD 303 Query: 372 FYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFG 431 N + ++ G+ + G +A + V + FA L+K + T G + Sbjct: 304 RLWANARQFREQMSAAGFTLAGADHAI-IPVMLGDAVVAQKFARELQKEGIYVT-GFFYP 361 Query: 432 PGGEGFVRV----SAFGHRENILEACRRFKQLYK 461 +G R+ SA E I A F ++ K Sbjct: 362 VVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK 395 >3VK2-A nrPDB Length = 398 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 37/257 (14%), Positives = 79/257 (30%), Gaps = 40/257 (15%) Query: 131 AEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAY 190 R A + GL + G S L + + + + Y Sbjct: 65 PTLNLLEARMASLEGGEAGLALA-------SGMGAITSTLWTLLRPGDEVLLGNTLYGH- 116 Query: 191 VDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAA 250 + + G+F ++ + + + T +I+F SP NP Sbjct: 117 -TFAFLHHGIGEFGVKLRHVDMADLQAL--------EAAMTPATRVIYFESPANP---NM 164 Query: 251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFT 310 + + + A+K+G+ +V D+ Y + P + S +KY Sbjct: 165 HMADIAGVAKIARKHGATVVVDNTY--------CTPYLQRPLELGADLVVHSATKYLSGH 216 Query: 311 G-VRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKV 369 G + G V + L+ KD + + + A L G++ ++ Sbjct: 217 GDITAGIVVGSQALVDRIRLQGLKDMTGAVLSPHD-----------AALLMRGIKTLNLR 265 Query: 370 IGFYKENTNIIIDTFTS 386 + + N ++ + Sbjct: 266 MDRHCANAQVLAEFLAR 282 >4U1T-A nrPDB Length = 389 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 29/180 (16%), Positives = 59/180 (32%), Gaps = 21/180 (11%) Query: 97 GIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDD 156 G P +++ ++A + + G G + L +A GL Sbjct: 18 SAGTGDVVPPIHVSTTYERRAQD--EPRYFYGRGENPTREELEECLA-----GLERAPFA 70 Query: 157 VFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYM 216 S G + + L + + D Y G G F+ ++ + Y Sbjct: 71 TVFSSG-QAAAATLLSLVRPGQCVVSTDDVY---------AGTDGLFDLAARQGVRVRYA 120 Query: 217 RCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA 276 T G L+ +++ +P NP + ++ A + G+ +V D+ +A Sbjct: 121 DLTTPEGIAAALAE-PDLALVWIETPTNPLLTVVD---VAEVSRRAHERGARVVVDNTFA 176 >5I92-A nrPDB Length = 435 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 41/303 (13%), Positives = 87/303 (28%), Gaps = 39/303 (12%) Query: 158 FVSDGAKCDISRLQVM--FGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 215 VS G + +S +++ + +I + Y + DS ++ +G V + Sbjct: 119 MVSSGTEATMSAIRLARGYTGRDSIIKFEGCYHGHSDSLLVKAGSGALTFGVPNSPGVPA 178 Query: 216 --------MRCTPENGFFPDLSTVGRTDIIFFCSP--NNPTGAAATREQLTQLVEFAKKN 265 + L VG+ P N L L E ++ Sbjct: 179 AFAKHTLTLPFNDIEAVRKTLGEVGKEVACIIVEPVAGNMNCVPPAPGFLEGLREACDEH 238 Query: 266 GSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLY 325 G ++++D + ++ V + ++F K G G+ +G K+ + Sbjct: 239 GVVLIFDEVMTGF-----RVALGGAQAYYGVTPDLSTFGKIIG-GGMPVG-AFGGKREIM 291 Query: 326 SDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKEN-TNIIIDTF 384 P+ + + ++ A L L H + Y + + Sbjct: 292 QQISPLGPVYQ----AGTLSGNPLAMAAGLTTLRLISRPGFHDELTAYTTRMLDGLQQRA 347 Query: 385 TSLGYDVYGGK-NAPYVW-------------VHFPNQSSWDVFAEILEKTHVVTTPGSGF 430 + G + + V + + F ++ V P S F Sbjct: 348 DAAGIPFVTTQAGGMFGLYFSGADAIVTFEDVMASDVERFKRFFHLMLDGGVYLAP-SAF 406 Query: 431 GPG 433 G Sbjct: 407 EAG 409 >3QI6-A nrPDB Length = 392 Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 36/272 (13%), Positives = 80/272 (29%), Gaps = 26/272 (9%) Query: 159 VSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRC 218 S G L+ M + + D +Y G T + V N+EY Sbjct: 87 FSSGMAAADCALRAMLRPGDHVVIPDDAY----------GGTFRLIDKVFTGWNVEYTPV 136 Query: 219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMY 278 + + T +I+ +P NP + + + + + + ++ D+ +A Sbjct: 137 ALADLDAVRAAIRPTTRLIWVETPTNP---LLSIADIAGIAQLGADSSAKVLVDNTFAS- 192 Query: 279 MSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRI 338 + P + + S +KY G +G ++ F ++ Sbjct: 193 -------PALQQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAGA 245 Query: 339 ICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKEN---TNIIIDTFTSLGYDVYGGK 395 + F+ + L E V F E+ + ++ S + Sbjct: 246 VPGPFDAYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAAR 305 Query: 396 N--APYVWVHFPNQSSWDVFAEILEKTHVVTT 425 V ++ ++ KT++ Sbjct: 306 QMRGFGGMVSVRMRAGRTAAEQLCAKTNIFIL 337 >4PIW-A nrPDB Length = 396 Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 37/329 (11%), Positives = 89/329 (27%), Gaps = 45/329 (13%) Query: 119 ELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFG--S 176 EL ++ G G G + G V ++ + ++ Sbjct: 33 ELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAK--VLLTPSCTASLEMAALLLDIQP 90 Query: 177 NVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI 236 + + ++ + ++ V+ G F NI+ + + +T + Sbjct: 91 GDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNIDET--------LIEAAITDKTRV 142 Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEV 296 I P A ++ ++ AKK+ +V D+A + + G Sbjct: 143 IV------PVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMSTYKG--RALGTIGH--- 191 Query: 297 AMETASF--SKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS---- 350 + SF +K G G T+I K L + + + Sbjct: 192 -IGCFSFHETKNYTAGGE-GGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDI 249 Query: 351 ---------QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYG-GKN---- 396 QA L + + ++ + + + ++ Sbjct: 250 GSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCVQN 309 Query: 397 APYVWVHFPNQSSWDVFAEILEKTHVVTT 425 A ++ + L++ ++ Sbjct: 310 AHMFYIKLRDIDDRSALINFLKEAEIMAV 338 >3DR4-A nrPDB Length = 391 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 43/248 (17%), Positives = 79/248 (31%), Gaps = 37/248 (14%) Query: 157 VFVSDGAKCDISRLQVM-FGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 215 + ++G L M G + V +Y A +S G T + + N++ Sbjct: 75 IACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYCGATPVLVDNDPRTFNLDA 134 Query: 216 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 + RT I P + G + ++E A+++ +++ D+A Sbjct: 135 AKLEAL--------ITPRTKAIM---PVHLYGQICDMD---PILEVARRHNLLVIEDAAE 180 Query: 276 AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDF 335 A+ + +S G+ + F TG G L + + Sbjct: 181 AVGATYRGKKS-----GSLGDCATFSFFGNAIITTGE-GGMITTNDDDLAAKMRLLRGQG 234 Query: 336 NRIICTCF-------NGASNISQAGALACLT--PEGLEAMHKVIGFYKENTNIIIDTFTS 386 + +NI A LA L E L A +V+G+Y++ Sbjct: 235 MDPNRRYWFPIVGFNYRMTNIQAAIGLAQLERVDEHLAARERVVGWYEQK-------LAR 287 Query: 387 LGYDVYGG 394 LG V Sbjct: 288 LGNRVTKP 295 >5VMB-A nrPDB Length = 425 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 60/392 (15%), Positives = 117/392 (29%), Gaps = 46/392 (11%) Query: 65 MSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELST-I 123 + + PE+A+ ++ + I L I P V+ + +K ++ + Sbjct: 10 FANISISEFDPELAQAIASEDERQEAH--IEL-IASENYCSPAVMEAQGSKLTNKYAEGY 66 Query: 124 EGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQ 183 G YG + + G +V G++ + + + T+ Sbjct: 67 PGKRYYGGCEFVDVIEQMAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVLGM 126 Query: 184 DPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPN 243 ++ ++ + +G+ VQ N E E L + +I Sbjct: 127 SLAHGGHLTHGAKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEH--KPRMIVAGF-- 182 Query: 244 NPTGAAATR-EQLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAMETA 301 +A +R + + A K G+ + D A+ A ++ + +I Sbjct: 183 ----SAYSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTH-- 236 Query: 302 SFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPE 361 K G R G + ++ F G A+A Sbjct: 237 ---KTLR--GPRSGLILAKANEEIEK---------KLQSAVFPGNQGGPLMHAIAAKAIC 282 Query: 362 GLEAMHKVIGFYK----ENTNIIIDTFTSLGYDVY--GGKNAPYVWVHFPNQSSWDVFAE 415 EAM Y+ +N + + F + GYDV G N ++ + Sbjct: 283 FKEAMSDDFKAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADA 342 Query: 416 ILEKTHVVTT-------PGSGFGPGGEGFVRV 440 L H+ P S F G +R+ Sbjct: 343 WLGAAHITVNKNSVPNDPRSPFVTSG---IRI 371 >2DKJ-A nrPDB Length = 407 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 52/337 (15%), Positives = 93/337 (27%), Gaps = 30/337 (8%) Query: 107 EVITSAMAKKAHE--LSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAK 164 + + A+ G YG + + + + G +V G++ Sbjct: 37 KQVREAVGSVLTNKYAEGYPGARYYGGCEVIDRVESLAIERAKALFGAAWANVQPHSGSQ 96 Query: 165 CDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGF 224 +++ + T+ D + ++ + +G+ V + E Sbjct: 97 ANMAVYMALMEPGDTLMGMDLAAGGHLTHGSRVNFSGKLYKVVSYGVRPDTELIDLEEVR 156 Query: 225 FPDLSTVGRTDIIFFCSPNNPTGAAATREQL--TQLVEFAKKNGSIIVYDSAY-AMYMSD 281 L + + GA+A E A + G+ +V D A+ A ++ Sbjct: 157 RLALEHRPK---VIVA------GASAYPRFWDFKAFREIADEVGAYLVVDMAHFAGLVAA 207 Query: 282 DNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICT 341 + P A V T K G R G + L + F I Sbjct: 208 GLHPNPL--PYAHVVTSTTH---KTLR--GPRGGLILSNDPELGKRIDKLI--FPGIQGG 258 Query: 342 CFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYD-VYGGKNAPYV 400 L PE E V+ EN + + GY V GG + Sbjct: 259 PLEHVIAGKAVAFFEALQPEFKEYSRLVV----ENAKRLAEELARRGYRIVTGGTDNHLF 314 Query: 401 WVHF-PNQSSWDVFAEILEKTHVVTTP-GSGFGPGGE 435 V P + E L+ + F P Sbjct: 315 LVDLRPKGLTGKEAEERLDAVGITVNKNAIPFDPKPP 351 >3WGB-A nrPDB Length = 341 Score = 44.8 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 47/338 (13%), Positives = 104/338 (30%), Gaps = 39/338 (11%) Query: 129 YGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPS-- 186 YG + G L A A + FV G ++ + + + Sbjct: 35 YGEDPGVNALEAYGADLLGKEAAL-----FVPSGTMSNLLAVMSHCQRGEGAVLGSAAHI 89 Query: 187 YPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPT 246 Y S ++G +Q G++ PD T ++ + +N Sbjct: 90 YRYEAQGSAVLGSVALQPVPMQADGSLALADVRAAIA--PDDVHFTPTRLVCLENTHN-- 145 Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKY 306 G L ++ E ++G + D A + ++ E+ + SK Sbjct: 146 GKVLPLPYLREMRELVDEHGLQLHLDGARLFNAVVASGHTVRELVAPFDSVSIC--LSKG 203 Query: 307 AGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAM 366 G V + A+ +++ A ++QAG A + + Sbjct: 204 LGAP-------VGSLLVGSHAFIARARRLRKMVGGGMRQAGILAQAGLFAL-----QQHV 251 Query: 367 HKVIGFYKENTNII--IDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVT 424 ++ ++ + + + D+ + V++ + S + A ++ ++ Sbjct: 252 VRLADDHRRARQLAEGLAALPGIRLDLAQVQTNM-VFLQLTSGESAPLLA-FMKARGIL- 308 Query: 425 TPGSGFGPGGEGFVRVS--AFGHRENILEACRRFKQLY 460 F GE +R+ H ++I E F + Sbjct: 309 -----FSGYGE--LRLVTHLQIHDDDIEEVIDAFTEYL 339 >4J5U-A nrPDB Length = 420 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 53/332 (15%), Positives = 101/332 (30%), Gaps = 39/332 (11%) Query: 108 VITSAMAKKAHELSTIEGYSGYGAEQ---GAKPLRAA---IAKTFYGGLGIGDDDVFVSD 161 ++ A+ + L T + GY +++ G + + A + +V Sbjct: 38 FVSPAVLEAQGALLTNKYAEGYPSKRFYNGCEEVDKAENLAIERVKKLFNCKYANVQPHS 97 Query: 162 GAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQ-FNTDVQKYGNIEYMRCTP 220 G++ + + + T+ ++ +G+ FN Y+ Sbjct: 98 GSQANQAVYLALLQPGDTVLGMSLDSGGHLTHGAAPNMSGKWFNAVSYSVNKETYLIDYD 157 Query: 221 ENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY-AMYM 279 E DL F P N + E K G+ + D A+ A + Sbjct: 158 EIERLADLHKPKLLIAGFSAYPRN--------IDFAKFREIVDKVGAYFMADIAHIAGLV 209 Query: 280 SDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRII 339 + +S IP A V T K G R G + + + ++I Sbjct: 210 ATGEHQSP--IPYAHAVTSTTH---KTLR--GPRGGLILSNDEEI----------GHKIN 252 Query: 340 CTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKE----NTNIIIDTFTSLGYDV-YGG 394 F G +A LE + Y + N + + GYD+ GG Sbjct: 253 SALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVISNAKALASSLQERGYDILTGG 312 Query: 395 KNAPYVWVHFP-NQSSWDVFAEILEKTHVVTT 425 + V V + + + A L++ + Sbjct: 313 TDNHIVLVDLRKDGITGKLAANSLDRAGITCN 344 >4L0O-H nrPDB Length = 388 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 31/193 (16%), Positives = 57/193 (29%), Gaps = 16/193 (8%) Query: 90 DAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGG 149 ++I GI + V + I + GY + P R A+ + Sbjct: 4 QTKLIHGGISE-DATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADL 62 Query: 150 LGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQK 209 G F S I + + S + + D Y G T + V Sbjct: 63 EGGVKGFAFAS--GLAGIHAVFSLLQSGDHVLLGDDVY----------GGTFRLFNQVLV 110 Query: 210 YGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSII 269 + + + T ++ +P+NP L Q AK +G + Sbjct: 111 KNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNP---LLKITDLAQCASVAKDHGLLT 167 Query: 270 VYDSAYAMYMSDD 282 + D+ +A + Sbjct: 168 IVDNTFATPYYQN 180 >5TXT-B nrPDB Length = 491 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 32/217 (14%), Positives = 61/217 (28%), Gaps = 35/217 (16%) Query: 251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD-------------NPRSIFEIPGAEE-- 295 + + ++ + A K G++ D +A+ + + S P + Sbjct: 203 SVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKG 262 Query: 296 --------VAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGAS 347 V M T + K G G G+ +KL+ + F Sbjct: 263 GAKTVMDRVDMITGTLGKSFGSVG---GYVAASRKLID-----WFRSFAPGFIFTTTLPP 314 Query: 348 NISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ 407 ++ A + +++T + F LG V + V V N Sbjct: 315 SVMAGATAAIRYQRCHIDLRTSQ---QKHTMYVKKAFHELGIPVI-PNPSHIVPVLIGNA 370 Query: 408 SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFG 444 ++IL H + F G R+ Sbjct: 371 DLAKQASDILINKHQIYVQAINFPTVARGTERLRITP 407 >5LL2-A nrPDB Length = 480 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 31/198 (15%), Positives = 62/198 (31%), Gaps = 18/198 (9%) Query: 181 AVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFC 240 + + Y DS + + ++ + + P F P T + Sbjct: 196 MLPSVVHVPYPDSYRTYPGETEHDVSLRYFNEFK----KPFESFLP----ADETACVLIE 247 Query: 241 SPNNPTGAAATREQLTQLV-EFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAME 299 G E+ QLV +F ++G + D ++ I +++ + Sbjct: 248 PIQGDGGIIKAPEEYMQLVYKFCHEHGILFAIDEVNQGL---GRTGKMWAIQQFKDIEPD 304 Query: 300 TASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 S K +G+ L + K+++ S P + T N + + L + Sbjct: 305 LMSVGKSLA-SGMPLSAVIGKKEVMQSLDAPAH-----LFTTAGNPVCSAASLATLDVIE 358 Query: 360 PEGLEAMHKVIGFYKENT 377 EGL G Y + Sbjct: 359 YEGLVEKSATDGAYAKQR 376 >3I5T-A nrPDB Length = 476 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 38/310 (12%), Positives = 74/310 (23%), Gaps = 42/310 (13%) Query: 110 TSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISR 169 + + + Y+ + R +A+ + +F + G + Sbjct: 72 RREIVDAMAHQAMVLPYASPWYMATSPAAR--LAEKIATLTPGDLNRIFFTTGGSTAVDS 129 Query: 170 LQVMFGSNVTIAVQDPS-------YPAYVDSSVIMGQTGQFNTDVQKYG----------- 211 F + P Y Y S+ + + + Sbjct: 130 ALR-FSEFYNNVLGRPQKKRIIVRYDGYHGSTALTAACTGRTGNWPNFDIAQDRISFLSS 188 Query: 212 -NIEYMRCTPENGFFPDL---------STVGRTDIIFFCSPNNPTGAA--ATREQLTQLV 259 N + + F DL S T F P +G + Sbjct: 189 PNPRHAGNRSQEAFLDDLVQEFEDRIESLGPDTIAAFLAEPILASGGVIIPPAGYHARFK 248 Query: 260 EFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319 +K+ + + D F V + +F+K GV G+ + Sbjct: 249 AICEKHDILYISDEV---VTGFGRCGEWFASEKVFGVVPDIITFAK-----GVTSGYVPL 300 Query: 320 PKKLLYSDGFPVAKDFNRIICTCFNGASNISQ-AGALACLTPEGLEAMHKVIGFYKENTN 378 + N NG + +Q A L L ++ +E + Sbjct: 301 GGLAISEAVLARISGENAKGSWFTNGYTYSNQPVACAAALANIELMEREGIVDQAREMAD 360 Query: 379 IIIDTFTSLG 388 SL Sbjct: 361 YFAAALASLR 370 >3WY7-A nrPDB Length = 404 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 30/197 (15%), Positives = 64/197 (32%), Gaps = 30/197 (15%) Query: 134 GAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDS 193 G L A LG + + S G ++ L + G I S+ + VD+ Sbjct: 99 GNTELHEAFEHQLASFLG-AESALVFSSGYTANLGALVALSGPGSLIVSDALSHASLVDA 157 Query: 194 SVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATRE 253 + + + E + T + + + Sbjct: 158 CRLSRARVVVSPHRDVDAVDAALAARTEE------------RAVVV------TESVFSAD 199 Query: 254 Q----LTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFE---IPGAEEVAMETASFSKY 306 L L +++G++++ D A+ + + + + + GA ++ M T + SK Sbjct: 200 GDLAPLRDLHAVCRRHGALLLVDEAHGLGVRGTRGQGLLHEVGLAGAPDIVMTT-TLSKA 258 Query: 307 AGFTGVRLGWTVIPKKL 323 G G G + P+ + Sbjct: 259 LGSQG---GAVLGPEAV 272 >3NYS-A nrPDB Length = 367 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 38/290 (13%), Positives = 75/290 (25%), Gaps = 37/290 (12%) Query: 115 KKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMF 174 K + + + Y L +A I + + +Q+ Sbjct: 17 KIDAGIQRVLRHGQYILGPEVTELEDRLADFVGAKYCISCAN------GTDALQIVQMAL 70 Query: 175 G--SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVG 232 G + +Y A ++ ++G + + N++ + + Sbjct: 71 GVGPGDEVITPGFTYVATAETVALLGAKPVYVDIDPRTYNLDPQ--------LLEAAITP 122 Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPG 292 RT I P + A K G ++ D+A + S RS Sbjct: 123 RTKAII------PVSLYGQCADFDAINAIASKYGIPVIEDAAQSFGASYKGKRS------ 170 Query: 293 AEEVAMETASF--SKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 350 + SF S G G G L + +A+ N Sbjct: 171 CNLSTVACTSFFPSAPLGCYG-DGGAIFTNDDELATAIRQIARHGQDRRYHHIRVGVNSR 229 Query: 351 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYV 400 A + LE + I ++ + +G P++ Sbjct: 230 LDTLQAAILLPKLEIFEEEIALRQKVAAEYDLSLKQVGI------GTPFI 273 >2C81-A nrPDB Length = 418 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 44/345 (12%), Positives = 105/345 (30%), Gaps = 53/345 (15%) Query: 104 PIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGA 163 P+ + +K E+ ++ G G + + AK F G+ V + G+ Sbjct: 10 EWPQH-SDRTRRKIEEVFQSNRWAISGYWTGEESMERKFAKAFADFNGV-PYCVPTTSGS 67 Query: 164 KCDISRLQVM-FGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPEN 222 + L+ + G + V ++ A + + + F DV+ + Sbjct: 68 TALMLALEALGIGEGDEVIVPSLTWIATATAVLNVNALPVF-VDVEADTYCIDPQLIKS- 125 Query: 223 GFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYD--SAYAMYMS 280 + +T I P + + ++ E A+++ ++ D ++ + Sbjct: 126 ------AITDKTKAII------PVHLFGSMANMDEINEIAQEHNLFVIEDCAQSHGSVWN 173 Query: 281 DDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFN---- 336 + +I +I S + T G V L+ + D Sbjct: 174 NQRAGTIGDIGAF--------SCQQGKVLTAGEGGIIVTKNPRLFELIQQLRADSRVYCD 225 Query: 337 ----------RIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTS 386 +++ SN + + + + L+ + ++N + D + Sbjct: 226 DSSELMHGDMQLVKKGDIQGSNYCLSEFQSAILLDQLQELDDKNAIREKNAMFLNDALSK 285 Query: 387 L-GYDVYG-----GKNAPYVW------VHFPNQSSWDVFAEILEK 419 + G V + Y + V F ++ + EK Sbjct: 286 IDGIKVMKRPPQVSRQTYYGYVFRFDPVKFGGLNADQFCEILREK 330 >5W1B-A nrPDB Length = 467 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 34/247 (13%), Positives = 70/247 (28%), Gaps = 36/247 (14%) Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSA-YAMYMSDDNPRSI-FEIPGAEEVAMETASFS 304 G + L ++ E AK++G +V DSA + R ++ +EV + ++ Sbjct: 198 GQPVSMSNLKEVYEIAKQHGIFVVMDSARFCENAYFIKARDPKYKNATIKEVIFDMYKYA 257 Query: 305 KYAGFTGVR-----LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 + + +G V + + + G + A + L Sbjct: 258 DALTMSAKKDPLLNIGGLVAIRDNEEIFTLARQRCVPMEGFVTYGGLAGRDMAAMVQGLE 317 Query: 360 PEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHF----PNQSSWDVFAE 415 E + D G + V+V P A+ Sbjct: 318 EGTEEEYLHYR---IGQVKYLGDRLREAGIPIQYPTGGHAVFVDCKKLVPQIPGDQFPAQ 374 Query: 416 -----ILEKTHVVTTPGSGFGPGGE-----------GFVRVSAFG------HRENILEAC 453 + ++ V F G + F+R++ H + I +A Sbjct: 375 AVINALYLESGVRAVEIGSFLLGRDPATGEQKHADMEFMRLTIARRVYTNDHMDYIADAL 434 Query: 454 RRFKQLY 460 K+ + Sbjct: 435 IGLKEKF 441 >2E7J-A nrPDB Length = 371 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 48/307 (15%), Positives = 91/307 (29%), Gaps = 21/307 (6%) Query: 87 KYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYS-GYGAEQGAKPLRAAIAKT 145 K I++ T + E A+ + S + + G E P I Sbjct: 3 KRETKDFINIDPLQTGGKLTEEARQALLEWGDGYSVCDFCTTGRLDEIKTPP----IHDF 58 Query: 146 FYGGLG--IGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQF 203 + L +G D V++GA+ + V D + S V + G Sbjct: 59 IHNQLPKFLGCDVARVTNGAREAKFAVMHSLAKKDAWVVMDE--NCHYSSYVAAERAGLN 116 Query: 204 NTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAK 263 V K +Y TPEN F + + + P G + ++ + Sbjct: 117 IALVPKTDYPDYA-ITPEN-FAQTIEETKKRGEVVLALITYPDGNYGNLPDVKKIAKVCS 174 Query: 264 KNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKL 323 + ++ + AYA+ P S+ EI S K +G +G + K+ Sbjct: 175 EYDVPLLVNGAYAI---GRMPVSLKEIGADF----IVGSGHKSMAASGP-IG-VMGMKEE 225 Query: 324 LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDT 383 ++ + + + L P E + + ++ + Sbjct: 226 WAEIVLRRSEKYKNKEVELLGCTARGATIITLMASFPHVRERIKRWDEEVEKARRFAAE- 284 Query: 384 FTSLGYD 390 LG Sbjct: 285 MEKLGIK 291 >3ECD-A nrPDB Length = 425 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 46/318 (14%), Positives = 88/318 (27%), Gaps = 30/318 (9%) Query: 123 IEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAV 182 G YG + A + A + G +V GA+ + + + + T+ Sbjct: 64 YPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVL- 122 Query: 183 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGF--FPDLSTVGRTDIIFFC 240 + G + R T + L+ + +I Sbjct: 123 ---GMSLDAGGHLTHGAKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAG 179 Query: 241 SPNNPTGAAATRE-QLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAM 298 +A R+ + A G+ ++ D A+ A ++ + E + Sbjct: 180 F------SAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAH-----V 228 Query: 299 ETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACL 358 T++ K G R G+ + + + + G AG Sbjct: 229 VTSTTHKTLR--GPRGGFVLTNDEEIAKKINSAVFPGLQ------GGPLMHVIAGKAVAF 280 Query: 359 TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYD-VYGGKNAPYVWVHF-PNQSSWDVFAEI 416 + I N + D + G D V GG + + V P + Sbjct: 281 GEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQA 340 Query: 417 LEKTHVVTTP-GSGFGPG 433 LE+ + G F P Sbjct: 341 LERAGITCNKNGIPFDPE 358 >1CS1-A nrPDB Length = 386 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 22/157 (14%), Positives = 48/157 (30%), Gaps = 23/157 (14%) Query: 153 GDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGN 212 G V + G V + Y G F++ ++ Sbjct: 67 GAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCY---------GGSYRLFDSLAKRGCY 117 Query: 213 -IEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVY 271 + ++ E L+ + ++ SP+NP + ++ A++ G++ V Sbjct: 118 RVLFVDQGDEQALRAALAE--KPKLVLVESPSNPLLRVVD---IAKICHLAREVGAVSVV 172 Query: 272 DSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 D+ + + P A + S +KY Sbjct: 173 DNTF--------LSPALQNPLALGADLVLHSCTKYLN 201 >1IBJ-A nrPDB Length = 464 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 52/168 (30%), Gaps = 20/168 (11%) Query: 105 IPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAK 164 P T+ + + + Y+ G R A+ L D + G Sbjct: 106 TPLYQTATFKQPSAIENGPYDYTR----SGNPT-RDALESLLAK-LDKADRAFCFTSG-M 158 Query: 165 CDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGF 224 +S + + + I D Y G + + + V + R Sbjct: 159 AALSAVTHLIKNGEEIVAGDDVY----------GGSDRLLSQVVPRSGVVVKRVNTTKLD 208 Query: 225 FPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYD 272 + +T +++ SP NP + ++ E A G++++ D Sbjct: 209 EVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEMAHAQGALVLVD 253 >4K2M-A nrPDB Length = 443 Score = 41.7 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 42/338 (12%), Positives = 101/338 (29%), Gaps = 44/338 (13%) Query: 101 TTEPIPEVIT-SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFV 159 P+ +IT + + L+ + + + + ++ + + Sbjct: 70 PFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYV-----IAT 124 Query: 160 SDGAKCDISRLQVM-FGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRC 218 S G + L + + + S+ A ++ + G + + I+ + Sbjct: 125 SSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPDKI 184 Query: 219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMY 278 + T I P + + + A + ++ D+ + Sbjct: 185 EE--------AITPYTKFIL------PVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIG 230 Query: 279 MSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD-------GFPV 331 ++D + ++ + + K G G + G + L GF V Sbjct: 231 LTD--------LGKYADITTLSFNPYKNFGVCG-KAGAIATDNEELAKKCIQFSYHGFEV 281 Query: 332 AKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNII-IDTFTSLGYD 390 ++I FN + QA L +++ + + I + + GY Sbjct: 282 NVKNKKVINFGFNSKMDNLQAAI--GLERMKYLSLNNFKRLFLADRYITQLAELQNKGYI 339 Query: 391 VYGGKNAPYVWVHFP----NQSSWDVFAEILEKTHVVT 424 + +VW FP + D+ ++ E V T Sbjct: 340 ELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQT 377 >3BB8-A nrPDB Length = 437 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 41/347 (11%), Positives = 85/347 (24%), Gaps = 72/347 (20%) Query: 140 AAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVM---------FGSNVTIAVQDPSYPAY 190 A K LG+ + + G+ ++ L + + +P Sbjct: 65 DAFEKKLGEYLGV-PYVLTTTSGSSANLLALTALTSPKLGVRALKPGDEVITVAAGFPTT 123 Query: 191 VDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAA 250 V+ ++ G F + N + + +T I G Sbjct: 124 VNPTIQNGLIPVFV--------DVDIPTYNVNASLIEAAVSDKTKAIMIAHT---LGNLF 172 Query: 251 TREQLTQLVEFAKKNGSIIVYD------SAYAM------------YMSDDNPRSIFEIPG 292 ++ + A K ++ D S Y ++ E Sbjct: 173 DLAEVRR---VADKYNLWLIEDCCDALGSTYDGKMAGTFGDIGTVSFYPAKHITMGEGGA 229 Query: 293 AEEVAMETASFSKYAG--------FTG------VRLGWTVIPKKLLYSDGFPVAKDFNRI 338 + E S + G R G + Y + + + Sbjct: 230 VFTQSAELKSIIESFRDWGRDCYCAPGCDNTCKKRFGQQLGSLPFGYDHKYTYSHLGYNL 289 Query: 339 ICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAP 398 T A ++Q LE + + + K N + D S + + Sbjct: 290 KITDMQAACGLAQ-----------LERIEEFVEKRKANFKYLKDALQSCADFIELPEAT- 337 Query: 399 YVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGH 445 + S + + E + V F + R+ G+ Sbjct: 338 ----ENSDPSWFGFPITLKEDSGVSRIDLVKFLDEAKVGTRLLFAGN 380 >3N0L-A nrPDB Length = 417 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 41/325 (12%), Positives = 86/325 (26%), Gaps = 37/325 (11%) Query: 123 IEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAV 182 G YG + + + +V + G++ + + I Sbjct: 57 YPGKRYYGGCEFVDEIETLAIERCKKLFNCKFANVQPNSGSQANQGVYAALINPGDKILG 116 Query: 183 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 D S+ ++ + +G+ ++ + +++ + +I Sbjct: 117 MDLSHGGHLTHGAKVSSSGKMYESCFYGVELDG---RIDYEKVREIAKKEKPKLIV---- 169 Query: 243 NNPTGAAATRE--QLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAME 299 GA+A + E A + G+ + D A+ A + S F P A V+ Sbjct: 170 ---CGASAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPF--PYAHVVSST 224 Query: 300 TASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 T K G R G + + L I G A Sbjct: 225 TH---KTLR--GPRGGIIMTNDEELAKKINSA------IFPGIQGGPLMHVIAAKAVGFK 273 Query: 360 PEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNA-------PYVWVHFPNQSSWDV 412 + + N ++ + + + ++ F + + Sbjct: 274 FNLSDEWKVYAKQVRTNAQVLANVLMDRKFKLV-SDGTDNHLVLMSFLDREFSGKDADLA 332 Query: 413 FAEILEKTHVVTTPG---SGFGPGG 434 + T PG S F G Sbjct: 333 LGNAGITANKNTVPGEIRSPFITSG 357 >1YJS-A nrPDB Length = 419 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 49/334 (14%), Positives = 104/334 (31%), Gaps = 38/334 (11%) Query: 123 IEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAV 182 G YG + + + G +V GA+ +++ + T+ Sbjct: 55 YPGRRYYGGCEYVDIVEELARERAKQLFGAEHANVQPHSGAQANMAVYFTVLEHGDTVLG 114 Query: 183 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 + S+ ++ + +G V + E ++ + + + R +I Sbjct: 115 MNLSHGGHLTHGSPVNFSGVQYNFVAYGVDPETHVIDYDD--VREKARLHRPKLIVAA-- 170 Query: 243 NNPTGAAATR-EQLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAMET 300 +A R + E A + G+ ++ D A+ A ++ + +P A V T Sbjct: 171 ----ASAYPRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNP--VPYAHFVTTTT 224 Query: 301 ASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALA-CLT 359 G R G + ++ AK ++ I G + A A Sbjct: 225 H-----QTLRGPRGGMILCQEQF--------AKQIDKAIFPGIQGGPLMHVIAAKAVAFG 271 Query: 360 PEGLEAMHKVIGFYKENTNIIIDTFTSLGYD-VYGGKNAPYVWVHF-PNQSSWDVFAEIL 417 + +N + + G+ V GG + + V P Q + ++L Sbjct: 272 EALQDDFKAYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVL 331 Query: 418 EKTHVVTT-------PGSGFGPGGEGFVRVSAFG 444 ++ + P S F G +R+ Sbjct: 332 DEVGITVNKNTIPYDPESPFVTSG---IRIGTAA 362 >6JEQ-A nrPDB Length = 675 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 35/120 (29%), Gaps = 6/120 (5%) Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGN---IEYMRCTPENGFFPDLSTVGRTDIIFFCSPNN 244 P +D +G T + Y E P + D + + P+N Sbjct: 195 PTGLDHITGLGVTHVQLLPIYDYSQESVDESRLDEPHYNWGYDPQNYNVPEGSYSTDPHN 254 Query: 245 PTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFS 304 P +L +L++ G ++ D Y +PG +FS Sbjct: 255 PAARIL---ELKRLIQKLHARGLRVIMDVVYNHVYDGYLIHFTKLVPGYYLRYKADRTFS 311 >2OGE-A nrPDB Length = 399 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 36/248 (14%), Positives = 65/248 (26%), Gaps = 26/248 (10%) Query: 161 DGAKCDISRLQVMF-----GSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 215 G + LQ+ G + V +Y A + G T + + ++ Sbjct: 82 VGVNSGMDALQLALRGLGIGPGDEVIVPSHTYIASWLAVSATGATPVPVEPHEDHPTLDP 141 Query: 216 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 + + + RT + P + L E A ++G IV D+A Sbjct: 142 L--------LVEKAITPRTRALL------PVHLYGHPADMDALRELADRHGLHIVEDAAQ 187 Query: 276 AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYS-DGFPVAKD 334 A I VA + K G G +L Sbjct: 188 AH----GARYRGRRIGAGSSVAAFSFYPGKNLGCFGDGGAVVTGDPELAERLRMLRNYGS 243 Query: 335 FNRIICTCFNGASNISQA-GALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYG 393 + S + + A+ + L++ + + +G V Sbjct: 244 RQKYSHETKGTNSRLDEMQAAVLRIRLAHLDSWNGRRSALAAEYLSGLAGLPGIGLPVTA 303 Query: 394 GKNAPYVW 401 P VW Sbjct: 304 PDTDP-VW 310 >5IJG-A nrPDB Length = 427 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 18/125 (14%), Positives = 34/125 (27%), Gaps = 4/125 (3%) Query: 141 AIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQT 200 I + + S G + L I P Y + + Sbjct: 86 EIVEDRLAVYEGAESAALFSSGMSAIATTLFAFVRPGDVILHSQPLY----GGTETLLAK 141 Query: 201 GQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVE 260 FN V+ + + + GR +I +P NPT + + ++ E Sbjct: 142 TFFNFGVEAVAFADGVHEATIEKAAEEALAKGRVSVILIETPANPTNSIVDVAAVRRVAE 201 Query: 261 FAKKN 265 + Sbjct: 202 KIEAR 206 >4P3M-A nrPDB Length = 429 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 54/366 (14%), Positives = 109/366 (29%), Gaps = 42/366 (11%) Query: 90 DAQVISLGIGDTTEPIPEVITSAMAKKAHELST-IEGYSGYGAEQGAKPLRAAIAKTFYG 148 I L I P V+ + ++ ++ + G YG + + + Sbjct: 26 QEDHIEL-IASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDVAESLAIERAKS 84 Query: 149 GLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 208 G +V G++ + + Q + TI ++ ++ + +G+ VQ Sbjct: 85 LFGADYANVQPHSGSQANAAVYQALCAPGDTILGMSLAHGGHLTHGSHVSFSGKMYNAVQ 144 Query: 209 KYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSI 268 E + + V + + +G + E A K G+ Sbjct: 145 YGITPE---TGILDYAEIERLAVEHKPTMIIAGFSAYSGIV----DWAKFREIADKVGAY 197 Query: 269 IVYDSAY-AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSD 327 + D A+ A ++ + +P A+ V T K G G R G + Sbjct: 198 LFVDMAHVAGLVAAGLYPNP--VPFADVVTTTTH---KTLG--GPRGGLILAKANEAIEK 250 Query: 328 GFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKE----NTNIIIDT 383 ++ F G +A E Y++ N ++ + Sbjct: 251 ---------KLNSAVFPGQQGGPLMHVIAAKAVAFKECAEPEFAVYQQQVLDNAKAMVKS 301 Query: 384 FTSLGYDVY--GGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTT-------PGSGFGPGG 434 F + GY + G +N ++ + L H+ P S F G Sbjct: 302 FLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALGNAHITVNKNSVPNDPRSPFVTSG 361 Query: 435 EGFVRV 440 +R+ Sbjct: 362 ---LRI 364 >5KQU-A nrPDB Length = 479 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 47/325 (14%), Positives = 92/325 (28%), Gaps = 35/325 (10%) Query: 84 HLLKYPDAQVISLGIGDTTEPI---PEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 + + ++I G I + A+ K+A EL+ Y G+ E + Sbjct: 62 RIRDHEGRELIDAFAGLYCVNIGYGRTEVADAIYKQAKELAYYHTYVGHSTEAIIELSSR 121 Query: 141 AIAKT--------FYGGLGIGDDDVFV--------SDGA---KCDISRLQVMFGSNVTI- 180 I +YG G ++ + G K ISR + GS + Sbjct: 122 IIRDWAPAGMKKVYYGLSGSDANETQIKLVRYYNNVLGRPQKKKIISRQRGYHGSGIMTG 181 Query: 181 -AVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIE---YMRCTPENGFFPDLSTVGRTDI 236 PS+ + D V + + ++ ++R + L+ T Sbjct: 182 SLTGLPSFHQHFDLPVEGIKHTVCPHWYKAPAGMDEAAFVRYCADELEKLILAEGPDTVA 241 Query: 237 IFFCSPNNPTGA--AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAE 294 F P TG + + K +++ D + + Sbjct: 242 AFIGEPVMGTGGIIVPPKGYWEAIQAVLNKYDVLLIADEVVCAFGRLGSKMGSQRYGMRP 301 Query: 295 EVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQA-- 352 ++ + L ++ +K+ K+ ++G + A Sbjct: 302 DLITTAKGLTSAYAP----LSAVIVGEKVWDVIEKASQKEGAMGHGWTYSGHPICAAAAL 357 Query: 353 GALACLTPEGLEAMHKVIGFYKENT 377 L L E L A +G Y Sbjct: 358 ANLDILERENLTANAADVGAYLNQR 382 >4IYO-A nrPDB Length = 397 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 19/144 (13%), Positives = 46/144 (31%), Gaps = 20/144 (13%) Query: 165 CDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGF 224 S + + + + D Y G F ++ +++ + Sbjct: 90 AATSTVMELLDAGSHVVAMDDLY---------GGTFRLFERVRRRTAGLDFSFVDLTDPA 140 Query: 225 FPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNP 284 + T +++ +P NP + + A+K+G + V D+ +A Sbjct: 141 AFKAAIRADTKMVWIETPTNP---MLKLVDIAAIAVIARKHGLLTVVDNTFAS------- 190 Query: 285 RSIFEIPGAEEVAMETASFSKYAG 308 + + P + + S +KY Sbjct: 191 -PMLQRPLSLGADLVVHSATKYLN 213 >1QO0-A nrPDB Length = 385 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 50/141 (35%), Gaps = 23/141 (16%) Query: 29 TRNACLPMAKRVNTCKCVATPQEKIEYKTKVSR-----NSNMSKLQA------------- 70 TR A +P+ +R + C TP E EY + N N + L A Sbjct: 87 TRKAVMPVVERADALLCYPTPYEGFEYSPNIVYGGPAPNQNSAPLAAYLIRHYGERVVFI 146 Query: 71 --GYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSG 128 Y++P + HL + V+ I P + + A+ + + + + Sbjct: 147 GSDYIYPRESNHVMRHLYRQHGGTVLE-EIYIPLYPSDDDLQRAVERIYQARADVVFSTV 205 Query: 129 YGAEQGAKPLRAAIAKTFYGG 149 G G L AIA+ + G Sbjct: 206 VGT--GTAELYRAIARRYGDG 224 >5KQT-A nrPDB Length = 479 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 36/306 (11%), Positives = 80/306 (26%), Gaps = 34/306 (11%) Query: 62 NSNMSKLQAGYLFPEIARRRS--AHLLKYPDAQVISLGIGDTTEPIPEVITS---AMAKK 116 N +L+ E A++ + + + +I L + P + ++ Sbjct: 82 NIGYGRLEVADAIHEQAKQLAYYHTYVGHASEAIIELSARIIRDWAPAGMKKVYYGLSGS 141 Query: 117 AHELSTIEGYSGYGAEQGAKPLRAAIAKTF-YGGLGIGDDDVFVSDGAKCDISRLQVMFG 175 + ++ Y G + I++ Y G G + G+ ++ F Sbjct: 142 DANETQVKLVRYYNNVLGRPQKKKIISRQRGYHGSG-------IVTGSLTGLASFHQHFD 194 Query: 176 SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTD 235 V V F ++R + L+ T Sbjct: 195 LPVE--------------GVKHTLCPHFYKAPAGMDEAAFVRHCAQELENLILAEGPDTV 240 Query: 236 IIFFCSPNNPTGA--AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGA 293 F P TG + + K +++ D + + Sbjct: 241 AAFIGEPVMGTGGIIVPPKGYWEAIQAVLAKYDVLLIADEVVCAFGRLGDKMGSQRHAMR 300 Query: 294 EEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAG 353 ++ + L ++ +K+ ++ ++G I A Sbjct: 301 PDLITTAKGLTSAYAP----LSAVIVGEKVWDVIDSASTREGAMGHGWTYSGHP-ICAAA 355 Query: 354 ALACLT 359 ALA L Sbjct: 356 ALANLD 361 >4WXB-A nrPDB Length = 428 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 32/260 (12%), Positives = 67/260 (25%), Gaps = 19/260 (7%) Query: 123 IEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAV 182 G YG + + G +V G++ + + + T+ Sbjct: 71 YPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVM- 129 Query: 183 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 + G F+ + + + + + L+ + Sbjct: 130 ---GMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVA- 185 Query: 243 NNPTGAAATR-EQLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAMET 300 +A +R + E A G+ ++ D A+ A ++ + S +P A T Sbjct: 186 ---GASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSP--VPYAHVTTTTT 240 Query: 301 ASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTP 360 K G R G + + + F + L P Sbjct: 241 H---KTLR--GPRGGLILTDDEDIAKKLNSAV--FPGLQGGPLEHVIAAKAVALKEALDP 293 Query: 361 EGLEAMHKVIGFYKENTNII 380 E VI ++ Sbjct: 294 AFKEYGENVIKNAAAMADVF 313 >3GBX-A nrPDB Length = 420 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 52/393 (13%), Positives = 117/393 (29%), Gaps = 53/393 (13%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELST-IEGYSGYGAEQGAKPLR 139 ++ K + I L I P V+ + ++ ++ + G YG + + Sbjct: 20 QAMEQEKVRQEEHIEL-IASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVE 78 Query: 140 AAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQ 199 G +V G++ + + + T+ + + ++ + Sbjct: 79 QLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNF 138 Query: 200 TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLV 259 +G+ V + E L+ + +I + +G ++ Sbjct: 139 SGKLYNIVPYGIDESGKIDYDEMAK---LAKEHKPKMII-GGFSAYSGVV----DWAKMR 190 Query: 260 EFAKKNGSIIVYDSAY------AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVR 313 E A G+ + D A+ A + P + + G R Sbjct: 191 EIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKT------------LAGPR 238 Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY 373 G + + + ++ F A +A EAM Y Sbjct: 239 GGLILA--------KGGDEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKVY 290 Query: 374 K----ENTNIIIDTFTSLGYDVYGGKNAPYVW-VHFPNQS-SWDVFAEILEKTHVVTT-- 425 + +N +++ F + GY V G +++ + +++ + L + ++ Sbjct: 291 QQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNKN 350 Query: 426 -----PGSGFGPGGEGFVRV-SAFGHRENILEA 452 P S F G +R+ S R EA Sbjct: 351 SVPNDPKSPFVTSG---IRIGSPAVTRRGFKEA 380 >2GMS-A nrPDB Length = 390 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 44/327 (13%), Positives = 91/327 (27%), Gaps = 79/327 (24%) Query: 143 AKTFYGGLGIGDDDVFVSDGAKCDISRLQVMF-------GSNVTIAVQDPSYPAYVDSSV 195 AKTF V VS G+ ++ + +F I V S+ Sbjct: 44 AKTFGSKYA-----VMVSSGSTANLLMIAALFFTKKPRLKKGDEIIVPAVSWS------- 91 Query: 196 IMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGR-----TDII----FFCSPNNPT 246 +Q+YG N D+ ++ T I +PNN Sbjct: 92 ------TTYYPLQQYGLRVKFVDIDINTLNIDIESLKEAVTDSTKAILTVNLLGNPNN-- 143 Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKY 306 ++ + I++ D+ +M + +N +FS + Sbjct: 144 --------FDEINKIIGGRDIILLEDNCESMGATFNNK--------CAGTFGLMGTFSSF 187 Query: 307 AG--FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGAS----------------- 347 + G V + +Y + N + Sbjct: 188 YSHHIATMEGGCIVTDDEEIYHILLCIRAHGWTRNLPKKNKVTGVKSDDQFEESFKFVLP 247 Query: 348 --NISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTS---LGYDVYGGKNAPYVWV 402 N+ + E L+ + + I ++N +D F L G+++ + + Sbjct: 248 GYNVRPLEMSGAIGIEQLKKLPRFISVRRKNAEYFLDKFKDHPYLDVQQETGESSWFGFS 307 Query: 403 HFPNQSSWDVFAEILEK---THVVTTP 426 + S + +++E + P Sbjct: 308 FIIKKDSGVIRKQLVENLNSAGIECRP 334 >3GJU-A nrPDB Length = 460 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 22/156 (14%), Positives = 40/156 (25%), Gaps = 27/156 (17%) Query: 128 GYGAEQGAKPLRAAIAKTF-YGGLGIGDDDVFVSDGAKCDISRLQVMFG-SNVTIA-VQD 184 Y G + I++ Y G G V G+ + F + + Sbjct: 134 YYNNVLGRPEKKKIISRWRGYHGSG-------VMTGSLTGLDLFHNAFDLPRAPVLHTEA 186 Query: 185 PSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNN 244 P Y F + ++ + + L+ T F P Sbjct: 187 PYY---------------FRRTDRSMSEEQFSQHCADKLEEMILAEGPETIAAFIGEPIL 231 Query: 245 PTGAAATRE--QLTQLVEFAKKNGSIIVYDSAYAMY 278 TG ++ KK ++V D + Sbjct: 232 GTGGIVPPPAGYWEKIQAVLKKYDVLLVADEVVTGF 267 >4GSA-A nrPDB Length = 432 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 33/299 (11%), Positives = 84/299 (28%), Gaps = 45/299 (15%) Query: 158 FVSDGAKC--DISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEY 215 FV+ G + + RL + I + Y + D ++ +G + + Sbjct: 118 FVNSGTEACMAVLRLMRAYTGRDKIIKFEGCYHGHADMFLVKAGSGVATLGLPSSPGVPK 177 Query: 216 MRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGA------------AATREQLTQLVEFAK 263 N + + +F +P G L L E Sbjct: 178 KTTA--NTLTTPYNDLEAVKALFAENPGEIAGVILEPIVGNSGFIVPDAGFLEGLREITL 235 Query: 264 KNGSIIVYDSAYAMY--MSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321 ++ +++V+D + P + K G G+ +G + Sbjct: 236 EHDALLVFDEVMTGFRIAYGGVQEKFGVTPD-------LTTLGKIIG-GGLPVGAYGGKR 287 Query: 322 KLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKEN-TNII 380 +++ VA +G + ++ + L ++ + + ++ + Sbjct: 288 EIMQ----LVAPAGPMYQAGTLSG-NPLAMTAGIKTLELLRQPGTYEYLDQITKRLSDGL 342 Query: 381 IDTFTSLGYDVYGGK-NAPYVWVHFPN---------QSSWDVFAEILE---KTHVVTTP 426 + G+ GG+ + + + +S F+ + + P Sbjct: 343 LAIAQETGHAACGGQVSGMFGFFFTEGPVHNYEDAKKSDLQKFSRFHRGMLEQGIYLAP 401 >3GZD-A nrPDB Length = 440 Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 48/311 (15%), Positives = 91/311 (29%), Gaps = 39/311 (12%) Query: 102 TEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSD 161 T P+ + AM K E + S Y A + AK + A ++ +G D+ + Sbjct: 34 TTPLEPEVIQAMTKAMWE-AWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTS 92 Query: 162 GAKCD----ISRLQVMFGSNVT-----------IAVQDPSY-PAYVDSSVIMGQTGQFNT 205 G I + F +N T + P + + V+ I Sbjct: 93 GGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVE 152 Query: 206 DVQKYGNIEYMRCTPENGFFPDLSTVGR--TDIIFFCSPNNPTGAAATREQLTQLVE--- 260 + + D+ R T ++ NN TG +++Q ++ Sbjct: 153 EQVAAVTFVPVSKVSGQTEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALN 212 Query: 261 ---FAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG-- 315 A I+V+ A R E G + + + F G R+G Sbjct: 213 QERVAAGLPPILVHTDAAQAL---GKQRVDVEDLGVDFLTIV------GHKFYGPRIGAL 263 Query: 316 WTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKE 375 + + R I+ G A L + EA + ++ Sbjct: 264 YIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHM---RD 320 Query: 376 NTNIIIDTFTS 386 + + + + Sbjct: 321 VRDYLEERLEA 331 >5KR6-A nrPDB Length = 479 Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 32/240 (13%), Positives = 60/240 (25%), Gaps = 39/240 (16%) Query: 128 GYGAEQGAKPLRAAIAKTF-YGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDP- 185 Y G + I++ Y G GI ++ L +P Sbjct: 153 YYNNVLGRPQKKKIISRQRGYHGSGIM----------TGSLTGLPAFHNHFD--LPLEPI 200 Query: 186 ---SYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSP 242 + P Y + M E+ R + L+ T F P Sbjct: 201 RHTTCPHYYRAPAGMS-------------EAEFSRHCADELEKMILAEGPDTVAAFIGEP 247 Query: 243 NNPTGAAATREQ--LTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET 300 TG + + K +++ D + + ++ Sbjct: 248 VMGTGGIVPPPEGYWEAIQAVLNKYDILLIADEVVCGFGRTGSMFGSHHYGMKPDLITVA 307 Query: 301 ASFSKYAG-FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLT 359 + +GV +G + ++ + + I I A ALA L Sbjct: 308 KGLTSAYAPLSGVIVG------EKVWKVLEQGSDQYGPIGHGWTYSGHPICAAAALANLD 361 >4BHD-A nrPDB Length = 428 Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 47/380 (12%), Positives = 102/380 (26%), Gaps = 50/380 (13%) Query: 105 IPEVITSAMA-KKAHELST-IEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDG 162 + A A H + + G Y + + + +V + G Sbjct: 33 TSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSG 92 Query: 163 AKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPEN 222 +++ + ++ + + + + E M + Sbjct: 93 VVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADA 152 Query: 223 GFFPDLSTVGRTDIIFFCSPNNPTGAAATREQ-LTQLVEFAKKNGSIIVYDSAYAMYMSD 281 L + +I F G+ + E A++ G+ I YD A+ + + Sbjct: 153 MVKKILEE--KPKLILFG------GSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIA 204 Query: 282 DNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICT 341 F+ P E S K P+ + A + + Sbjct: 205 GKQ---FQDPLREGAEYLMGSTHKTF----------FGPQGGVILTTKENADKIDSHVFP 251 Query: 342 CFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPY-- 399 ++ LA E LE +N + G++V ++ + Sbjct: 252 GVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVL-CEHKDFTE 310 Query: 400 ---VWVHFPNQSSWDV----FAEILEKTHVVT--------------TPGSGFGPGGEGFV 438 V + + + A++ E+ +++ P SG G + Sbjct: 311 SHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNP-SGIRLGTQECT 369 Query: 439 RVSAFGHR-ENILEACRRFK 457 R+ E I E +R Sbjct: 370 RLGMKEKEMEEIAEFMKRIA 389 >4OTL-A nrPDB Length = 423 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 49/327 (14%), Positives = 91/327 (27%), Gaps = 45/327 (13%) Query: 88 YPDAQVISLGIGDTTEPIPEVITSAMAKKAHELST-IEGYSGYGAEQGAKPLRAAIAKTF 146 I L I P V+ + ++ ++ + G YG + + Sbjct: 33 RRQEDHIEL-IASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRV 91 Query: 147 YGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTD 206 G +V + G++ + M TI S+ G + Sbjct: 92 KQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIM----------GMSLAHGGHLTHGSP 141 Query: 207 VQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATRE------QLTQLVE 260 V G + N + + P A +L + Sbjct: 142 VNMSGKWFNVVSYGLNENEDIDYDAAEK----LANEHKPKLIVAGASAFALKIDFERLAK 197 Query: 261 FAKKNGSIIVYDSA-YAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319 AK G+ ++ D A YA ++ + +P A+ V T G R G ++ Sbjct: 198 IAKSVGAYLMVDMAHYAGLIAAGVYPNP--VPHADFVTTTTHK-----SLRGPRGGVILM 250 Query: 320 PKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYK----E 375 + I F G +A EA+ Y+ E Sbjct: 251 KAEYE-----------KPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVE 299 Query: 376 NTNIIIDTFTSLGYDVYGGKNAPYVWV 402 N ++ +T G + G+ +V + Sbjct: 300 NARVLAETLVKRGLRIVSGRTESHVML 326 >3AEO-A nrPDB Length = 389 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 24/157 (15%), Positives = 46/157 (29%), Gaps = 21/157 (13%) Query: 159 VSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRC 218 G S + D Y V D+ ++E ++ Sbjct: 80 FGSGMGAISSSTLAFLQKGDHLIAGDTLYGCTVSLFTHWLPRFGIEVDLIDTSDVEKVK- 138 Query: 219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMY 278 + P+ T +++ SP NPT + + + G+ +V D+ + Sbjct: 139 ---AAWKPN------TKMVYLESPANPTCKV---SDIKGIAVVCHERGARLVVDATF--- 183 Query: 279 MSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315 + E+ + S SKY G +G Sbjct: 184 -TSPCFLKPLELGAD----IALHSVSKYINGHGDVIG 215 >5WT2-A nrPDB Length = 401 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 45/251 (17%), Positives = 82/251 (32%), Gaps = 32/251 (12%) Query: 136 KPLRAAIAKTFYGGLGIGDDDVFVSDGAKC-------DISRLQVMFGSNVTIAVQDPSYP 188 + A+ K + G DDV ++ A + + + I +P Sbjct: 46 PAIAEALDKLYKGINARDIDDVIITSCATESNNWVLKGVYFDECLKKGKNHIVTTVAEHP 105 Query: 189 AYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGA 248 A + + G T + E+ T E + +T ++ NN TG Sbjct: 106 AVRSTCNFLESLGVEVTYLPI---NEHGSITAEQVRE---AITEKTALVSVMWANNETGL 159 Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVA-METASFS--K 305 + ++ K+ G + D+ ++I +IP A + SFS K Sbjct: 160 IFP---IEEIGAICKEKGVLFHTDAV----------QAIGKIPVDVLKANADFLSFSAHK 206 Query: 306 YAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEA 365 + G G +G I + + F + N N I G L E L+ Sbjct: 207 FHGPKG--IGGLYIRSGVGLTPLFHGGEHMNGRRSGTLN-VPYIVGMGEAMKLAVEHLDY 263 Query: 366 MHKVIGFYKEN 376 +V+G ++ Sbjct: 264 EKEVVGKLRDK 274 >3NDN-A nrPDB Length = 414 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 17/116 (14%), Positives = 43/116 (37%), Gaps = 13/116 (11%) Query: 161 DGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTP 220 G + L + G+ + V + + G +++ ++ + Sbjct: 104 SGMAAVFTSLGALLGAGDRL----------VAARSLFGSCFVVCSEILPRWGVQTVFVDG 153 Query: 221 ENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA 276 ++ + + T +FF +P+NP + + + E A G+ +V D+ +A Sbjct: 154 DDLSQWERALSVPTQAVFFETPSNPMQSLVD---IAAVTELAHAAGAKVVLDNVFA 206 >3G8M-A nrPDB Length = 417 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 48/374 (12%), Positives = 105/374 (28%), Gaps = 49/374 (13%) Query: 81 RSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELST-IEGYSGYGAEQGAKPLR 139 ++ K + I L I P V+ + ++ ++ + G YG + + Sbjct: 17 QAMEQEKVRQEEHIEL-IASENYTSPRVMQAQGSQLTNKFAEGYPGKRYYGGCEYVDIVE 75 Query: 140 AAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQ 199 G +V G++ + + + T+ + ++ ++ + Sbjct: 76 QLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNF 135 Query: 200 TGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGR--TDIIFFCSPNNPTGAAATREQLTQ 257 +G + Y + Y + + DL + + + +G + Sbjct: 136 SG------KLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVV----DWAK 185 Query: 258 LVEFAKKNGSIIVYDSAY------AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTG 311 + E A G+ + D A+ A + P + + G Sbjct: 186 MREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKT------------LAG 233 Query: 312 VRLGWTV--IPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKV 369 R G + + LY + G AG L Sbjct: 234 PRGGLILAKGGSEELYKKLNSAVFPGGQ------GGPLMHVIAGKAVALKEAMEPEFKTY 287 Query: 370 IGFYKENTNIIIDTFTSLGYDVY-GGKNAPYVWVHFPNQS-SWDVFAEILEKTHVVTT-- 425 +N +++ F GY V GG + V +++ + L + ++ Sbjct: 288 QQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKN 347 Query: 426 -----PGSGFGPGG 434 P S F G Sbjct: 348 SVPNDPKSPFVTSG 361 >5KQW-A nrPDB Length = 479 Score = 36.7 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 23/172 (13%), Positives = 48/172 (27%), Gaps = 12/172 (6%) Query: 212 NIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQ--LTQLVEFAKKNGSII 269 +++R + L+ T F P TG Q + K ++ Sbjct: 217 EAQFVRYCADELEKLILAEGPDTVAAFIGEPVMGTGGIIPPPQGYWEAIQAVLNKYDILL 276 Query: 270 VYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG-FTGVRLGWTVIPKKLLYSDG 328 + D + + ++ + +GV +G + ++ Sbjct: 277 IADEVVCGFGRLGSKMGSQHYGMKPDLITVAKGLTSAYAPLSGVIVG------EKVWDVI 330 Query: 329 FPVAKDFNRIICTCFNGASNISQAGALA---CLTPEGLEAMHKVIGFYKENT 377 +++ + I A ALA L E L +G Y + Sbjct: 331 EKGSQEHGPMGHGWTYSGHPICAAAALANLDILERENLTGNAADVGAYLQQR 382 >3UWC-A nrPDB Length = 374 Score = 36.7 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 43/132 (32%), Gaps = 16/132 (12%) Query: 144 KTFYGGLGIGDDDVFVSDGAKCDISRLQVM-FGSNVTIAVQDPSYPAYVDSSVIMGQTGQ 202 + + L + V G +++ G+ + ++ A V + V G T Sbjct: 44 EKRFAALHNAPHAIGVGTGTDALAMSFKMLNIGAGDEVITCANTFIASVGAIVQAGATPV 103 Query: 203 FNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFA 262 Y PE + + +T I P + TG A L + A Sbjct: 104 LVDSENGY------VIDPEK---IEAAITDKTKAIM---PVHYTGNIADMP---ALAKIA 148 Query: 263 KKNGSIIVYDSA 274 KK+ IV D+ Sbjct: 149 KKHNLHIVEDAC 160 >2C44-A nrPDB Length = 471 Score = 35.5 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 34/223 (15%), Positives = 66/223 (29%), Gaps = 14/223 (6%) Query: 247 GAAATREQLTQLVEFAKKNGSIIVYDSA-YAMYMSDDNPRSI-FEIPGAEEVAMETASFS 304 G + L + AKK +V DSA +A R ++ E++ ET ++ Sbjct: 202 GQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYA 261 Query: 305 KYAGFTGVRLGWT-VIPKKLLYSDGFPVAKDFNRIICTCFNGASNI--SQAGALACLTPE 361 + + + + D F R +C G + GA+ L Sbjct: 262 DMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVG 321 Query: 362 GLEAMH-KVIGFYKENTNIIIDTFTSLGYDVYGGKN-APYV-----WVHFP--NQSSWDV 412 + M+ + + ++D +G A +V H P + + Sbjct: 322 LYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQAL 381 Query: 413 FAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRR 455 E+ + + F G + E + R Sbjct: 382 ACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPR 424 >5KR5-A nrPDB Length = 479 Score = 35.5 bits (80), Expect = 0.056, Method: Composition-based stats. Identities = 31/258 (12%), Positives = 63/258 (24%), Gaps = 36/258 (13%) Query: 128 GYGAEQGAKPLRAAIA-KTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPS 186 Y G + IA + Y G G + G+ + PS Sbjct: 153 YYNNVLGRPNKKKIIARERSYHGSG-------IVTGSLTGL-----------------PS 188 Query: 187 YPAYVDSS---VIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPN 243 + + D V + +++ E T F P Sbjct: 189 FHQHFDLPIDRVKHTVCPHWYNAPPGMSEAQFVAYCVEELEKLIAREGADTIAAFIAEPV 248 Query: 244 NPTGAAATREQ--LTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETA 301 TG Q + +K+ +++ D + + ++ Sbjct: 249 MGTGGIVPPPQGYWEAIQAVLRKHDILLIADEVVCGFGRLGSKTGSEHYGIKPDLITVAK 308 Query: 302 SFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQA--GALACLT 359 + L ++ +K+ + ++G + A L L Sbjct: 309 GLTSAYAP----LSAVIVSEKVWDVIEKGSREHGVMGHGWTYSGHPVCAAAALANLDILE 364 Query: 360 PEGLEAMHKVIGFYKENT 377 E L +G Y + Sbjct: 365 RENLTGNAADVGAYLQQR 382 >2CB1-A nrPDB Length = 412 Score = 34.8 bits (78), Expect = 0.086, Method: Composition-based stats. Identities = 35/203 (17%), Positives = 64/203 (31%), Gaps = 22/203 (10%) Query: 128 GYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSY 187 GY + P A+ + G + V ++ G + L + + Sbjct: 47 GYVYARQKDPTAKALEERLKALEG-ALEAVVLASGQAATFAALLALLRPGDEV------- 98 Query: 188 PAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTG 247 V + + GQT V + PE + + +T +F + NP Sbjct: 99 ---VAAKGLFGQTIGLFGQVLSLMGVTVRYVDPEPEAVRE-ALSAKTRAVFVETVANPAL 154 Query: 248 AAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYA 307 L L A++ G +V D+ + P A + S +K+A Sbjct: 155 LVPD---LEALATLAEEAGVALVVDNTFG-------AAGALCRPLAWGAHVVVESLTKWA 204 Query: 308 GFTGVRLGWTVIPKKLLYSDGFP 330 G LG V+ ++ +P Sbjct: 205 SGHGSVLGGAVLSRETELWRNYP 227 >5YZA-A nrPDB Length = 525 Score = 34.8 bits (78), Expect = 0.087, Method: Composition-based stats. Identities = 20/165 (12%), Positives = 50/165 (30%), Gaps = 11/165 (6%) Query: 84 HLLKYPDAQVISLGIGDTTEPI---PEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRA 140 ++ +++ LGI + PE + + +A ++ Y + +K Sbjct: 203 DIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAE 262 Query: 141 AIAKTFYGGLGIGDDDVFVSDGAKCD------ISRLQVMFGSNVTIAVQDPSYPAYVDSS 194 IA+ G + + + S G ++ S DP+ P +++S Sbjct: 263 VIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPP--LSPDPTTPDFLNSL 320 Query: 195 VIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFF 239 + G + + + P+ + + Sbjct: 321 LSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVI 365 >3RUY-A nrPDB Length = 392 Score = 34.4 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 25/214 (11%), Positives = 60/214 (28%), Gaps = 23/214 (10%) Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 L + +E KK + V D +F + V + K G Sbjct: 199 IPPAGFLKEALEVCKKENVLFVADEIQTGL---GRTGKVFAC-DWDNVTPDMYILGKALG 254 Query: 309 FTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHK 368 + + +L F G + ++ A ++A L E + + Sbjct: 255 GGVFPISCAAANRDILGV--------FEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTE 306 Query: 369 VIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGS 428 E ++ + + +++ + E L+ ++ Sbjct: 307 RSLQLGEK---LVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLC---- 359 Query: 429 GFGPGGEGFVRVS--AFGHRENILEACRRFKQLY 460 E +R++ E++ A ++ K + Sbjct: 360 --KETHENVIRIAPPLVISEEDLEWAFQKIKAVL 391 >2E8Y-A nrPDB Length = 718 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 37/257 (14%), Positives = 80/257 (31%), Gaps = 40/257 (15%) Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLT 256 +G T V + ++ + + + + + +P++P + +L Sbjct: 263 LGVTHVELLPVNDFAGVDEEKPLDAYNWGYNPLHFFAPEGSYASNPHDPQ---TRKTELK 319 Query: 257 QLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFS------------ 304 Q++ ++G ++ D + +N +PG E S Sbjct: 320 QMINTLHQHGLRVILDVVFNHVYKRENSPFEKTVPGYFFRHDECGKPSNGTGVGNDIASE 379 Query: 305 -----KY-----------AGFTGVR---LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNG 345 K+ G R LG I L + AK + ++ Sbjct: 380 RRMARKFIADCVVYWLEEYNVDGFRFDLLGILDIDTVLYMKEKATKAKPGILLFGEGWDL 439 Query: 346 ASNI--SQAGALA-CLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWV 402 A+ + Q ALA G+ + + +++ + G+ + G++A V Sbjct: 440 ATPLPHEQKAALANAPRMPGIGFFNDM---FRDAVKGNTFHLKATGFALGNGESAQAVMH 496 Query: 403 HFPNQSSWDVFAEILEK 419 S W A I+ + Sbjct: 497 GIAGSSGWKALAPIVPE 513 >5W70-A nrPDB Length = 445 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 21/145 (14%), Positives = 47/145 (32%), Gaps = 18/145 (12%) Query: 130 GAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVM-FGSNVTIAVQDPSYP 188 G +G + A+ F G+ V + G + L+ G+ + V S+ Sbjct: 66 GPYRGTESYERRFARAFAAYNGV-PHCVPAASGTASLMLALEACGIGAGDEVIVPGLSWV 124 Query: 189 AYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGA 248 A + + + F + + + +PE + + T I Sbjct: 125 ASGSTILGVNAVPIFC-----DVDPDTLCLSPEAV---EAAITEHTRAIVVV-------H 169 Query: 249 AAT-REQLTQLVEFAKKNGSIIVYD 272 + + L A+++G ++ D Sbjct: 170 LYSALADMDALSAIAERHGLPLIED 194 >6BXI-A nrPDB Length = 333 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 59/179 (32%), Gaps = 12/179 (6%) Query: 52 KIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITS 111 K ++T+ RN N L + + F + +R A K Q+ +G PEV Sbjct: 157 KKAHRTEFYRNLN-HSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQ 215 Query: 112 AMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDD------DVFVSDGAKC 165 K + ++ G Y G P + + Y + + +V +S+ AK Sbjct: 216 TGYNKLCDWWSL-GVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKD 274 Query: 166 DISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGF 224 I R F + P +S G + + +IE + F Sbjct: 275 LILR----FCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNF 329 >5JNF-C nrPDB Length = 587 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 51/168 (30%), Gaps = 17/168 (10%) Query: 139 RAAIAKTFYGGLGIGDDD--VFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVI 196 RA G G+ DD + D + I + + + DP YP + ++ Sbjct: 239 RANQLAHHLRGKGVKPDDQVAIMLDKSLDMIVSILAVMKAGGAYVPIDPDYPGERIAYML 298 Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPD--------LSTVGRT-DIIFFCSPNNPT- 246 + + C + PD L V R D+++ + T Sbjct: 299 ADSSAAILLTNALHEEKANGACDIIDVHDPDSYSENTNNLPHVNRPDDLVYVMYTSGSTG 358 Query: 247 ---GAAATREQLTQLVEFAKKNGSIIVYDSA--YAMYMSDDNPRSIFE 289 G L E+ + + D A Y+ + D + IF Sbjct: 359 LAKGVMIEHHNLVNFCEWYRPYFGVTPADKALVYSSFSFDGSALDIFT 406 >5ES8-A nrPDB Length = 776 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 51/168 (30%), Gaps = 17/168 (10%) Query: 139 RAAIAKTFYGGLGIGDDD--VFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVI 196 RA G G+ DD + D + I + + + DP YP + ++ Sbjct: 237 RANQLAHHLRGKGVKPDDQVAIMLDKSLDMIVSILAVMKAGGAYVPIDPDYPGERIAYML 296 Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPD--------LSTVGRT-DIIFFCSPNNPT- 246 + + C + PD L V R D+++ + T Sbjct: 297 ADSSAAILLTNALHEEKANGACDIIDVHDPDSYSENTNNLPHVNRPDDLVYVMYTSGSTG 356 Query: 247 ---GAAATREQLTQLVEFAKKNGSIIVYDSA--YAMYMSDDNPRSIFE 289 G L E+ + + D A Y+ + D + IF Sbjct: 357 LAKGVMIEHHNLVNFCEWYRPYFGVTPADKALVYSSFSFDGSALDIFT 404 >5ES6-A nrPDB Length = 685 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 51/168 (30%), Gaps = 17/168 (10%) Query: 139 RAAIAKTFYGGLGIGDDD--VFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVI 196 RA G G+ DD + D + I + + + DP YP + ++ Sbjct: 237 RANQLAHHLRGKGVKPDDQVAIMLDKSLDMIVSILAVMKAGGAYVPIDPDYPGERIAYML 296 Query: 197 MGQTGQFNTDVQKYGNIEYMRCTPENGFFPD--------LSTVGRT-DIIFFCSPNNPT- 246 + + C + PD L V R D+++ + T Sbjct: 297 ADSSAAILLTNALHEEKANGACDIIDVHDPDSYSENTNNLPHVNRPDDLVYVMYTSGSTG 356 Query: 247 ---GAAATREQLTQLVEFAKKNGSIIVYDSA--YAMYMSDDNPRSIFE 289 G L E+ + + D A Y+ + D + IF Sbjct: 357 LAKGVMIEHHNLVNFCEWYRPYFGVTPADKALVYSSFSFDGSALDIFT 404 >3FCR-A nrPDB Length = 458 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 22/156 (14%), Positives = 38/156 (24%), Gaps = 27/156 (17%) Query: 128 GYGAEQGAKPLRAAIAKTF-YGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAV--QD 184 Y G + I++ Y G G+ G+ + F V + + Sbjct: 133 YYNNILGRPEKKKIISRWRGYHGSGL-------VTGSLTGLELFHKKFDLPVEQVIHTEA 185 Query: 185 PSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNN 244 P Y D+ + C E + T F P Sbjct: 186 PYY--------------FRREDLNQTEEQFVAHCVAELEALIEREGAD-TIAAFIGEPIL 230 Query: 245 PTGAAATRE--QLTQLVEFAKKNGSIIVYDSAYAMY 278 TG + K+ ++V D + Sbjct: 231 GTGGIVPPPAGYWEAIQTVLNKHDILLVADEVVTGF 266 >4OBV-D nrPDB Length = 490 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 49/147 (33%), Gaps = 13/147 (8%) Query: 140 AAIAKTFYGGLGIGDD--DVFVSDGAKCDISRLQVMFGSNVT--------IAVQDPSYPA 189 + K +G ++ VFVS G+ +I+ L + +T + D ++ + Sbjct: 135 QEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSS 194 Query: 190 YVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAA 249 I+G T + + + E D G + + T Sbjct: 195 VAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETD-KKSGYIPFVVIGTAG--TTNT 251 Query: 250 ATREQLTQLVEFAKKNGSIIVYDSAYA 276 + + LT++ KK+ D AY Sbjct: 252 GSIDPLTEISALCKKHDMWFHIDGAYG 278 >3HMU-A nrPDB Length = 472 Score = 33.6 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 38/288 (13%), Positives = 78/288 (27%), Gaps = 29/288 (10%) Query: 112 AMAKKAHELSTIEGYSGYGAEQGAKPLRAAI--AKTFYGGLGIGDDDVFVS-----DGAK 164 A+A+K EL+ + + A G++ I +T++ G + V +S G+ Sbjct: 103 ALAQKLAELAPGDLNHVFFAGGGSEANDTNIRMVRTYWQNKGQPEKTVIISRKNAYHGST 162 Query: 165 CDISRLQVMFG-SNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENG 223 S L M G + + D +++ + G + + E+ Sbjct: 163 VASSALGGMAGMHAQSGLIPD---VHHINQPNWWAEGGDMDPE-------EFGLARAREL 212 Query: 224 FFPDLSTVGRTDIIFFCSPNNPTGAAATREQ--LTQLVEFAKKNGSIIVYDSAYAMYMSD 281 L F P G ++ K +++ D + Sbjct: 213 EEAILELGENRVAAFIAEPVQGAGGVIVAPDSYWPEIQRICDKYDILLIADEVICGFGRT 272 Query: 282 DNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICT 341 N + G M +K G+ G+ I ++ + V Sbjct: 273 GN-WFGTQTMGIRPHIMTI---AK-----GLSSGYAPIGGSIVCDEVAHVIGKDEFNHGY 323 Query: 342 CFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGY 389 ++G + E + V + T Sbjct: 324 TYSGHPVAAAVALENLRILEEENILDHVRNVAAPYLKEKWEALTDHPL 371 >6G4F-A nrPDB Length = 464 Score = 33.2 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 30/259 (11%), Positives = 74/259 (28%), Gaps = 40/259 (15%) Query: 49 PQEKIEYKTKVSRNSNMSKLQAGYLFPEIARR-RSAHLLKYPDAQVISLGIGDTTEPIPE 107 P++ I+Y+ N+ + + L P I R ++ I G + + Sbjct: 9 PEKDIQYQLHPYTNARLHQ----ELGPLIIERGEGIYVYDDQGKGYIEAMAGLWSAALGF 64 Query: 108 VITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDI 167 + + +T+ Y + + + +A+ + VF ++ Sbjct: 65 SNQRLIKAAEQQFNTLPFYHLFSHKSHRPSI--ELAEKLIEMAPVPMSKVFFTNSGSEAN 122 Query: 168 SRLQVMFGSNVTIAVQDPSYPAYVDSSV--------------IMGQTGQFNTDVQKYGNI 213 + M + A+ P+ ++ + G F+ + + ++ Sbjct: 123 DTVVKMVWY-LNNALGKPAKKKFISRVNGYHGITVASASLTGLPGNQRGFDLPLPGFLHV 181 Query: 214 ------EYMRCTPENGFFPD----------LSTVGRTDIIFFCSPNNPTGAA--ATREQL 255 + F D L+ T F P G R Sbjct: 182 GCPHHYRFALAGESEEHFADRLAVELEQKILAEGPETIAAFIGEPLMGAGGVIVPPRTYW 241 Query: 256 TQLVEFAKKNGSIIVYDSA 274 ++ + +K +++ D Sbjct: 242 EKIQKVCRKYDILVIADEV 260 >5KR3-A nrPDB Length = 479 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 22/163 (13%), Positives = 44/163 (26%), Gaps = 12/163 (7%) Query: 221 ENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQ--LTQLVEFAKKNGSIIVYDSAYAMY 278 E T F P TG Q + +K+ +++ D + Sbjct: 226 EELEKLIAREGADTIAAFIAEPVMGTGGIIPPPQGYWEAIQAVLRKHDILLIADEVVCGF 285 Query: 279 MSDDNPRSIFEIPGAEEVAMETASFSKYAG-FTGVRLGWTVIPKKLLYSDGFPVAKDFNR 337 + ++ + +GV +G + ++ +++ Sbjct: 286 GRLGSKMGSQHYGIKPDLITVAKGLTSAYAPLSGVIVG------EKVWDVIEKGSQEHGP 339 Query: 338 IICTCFNGASNISQAGALA---CLTPEGLEAMHKVIGFYKENT 377 + I A ALA L E L +G Y + Sbjct: 340 MGHGWTYSGHPICAAAALANLDILERENLTGNAADVGAYLQQR 382 >4IRN-A nrPDB Length = 416 Score = 32.8 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 108 VITSAMAKKAHELSTIEGYSGY-GAEQGAKPLRAAIAKTFYGGLG 151 I+ A + E I G GY + + LR AIA FY G Sbjct: 359 YISEAWVQSCLEAIEIHGAYGYLTNTELERELRDAIASKFYSGTS 403 >3MAF-B nrPDB Length = 518 Score = 32.4 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 38/247 (15%), Positives = 77/247 (31%), Gaps = 26/247 (10%) Query: 159 VSDGAKCDISRLQVMFGS--NVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYM 216 V+ G + + T + P +V+ +Y I+ + Sbjct: 169 VTSGGTESLLLAMKTYRDWARATKGITAP-------EAVVPVSAHAAFDKAAQYFGIKLV 221 Query: 217 RCTPENGFFPDLSTVGR-----TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVY 271 R + + D++ + T ++ +P P G + + ++ A ++G Sbjct: 222 RTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVV---DPIPEIAALAAEHGIGCHV 278 Query: 272 DSAYAMYMSDDNPRSIFEIPGAEEVAMETASFS----KY-AGFTGVRLGWTVIPKKLLY- 325 D+ ++ R + +P + S S KY G G + P L Y Sbjct: 279 DACLGGFILPWAERLGYPVPPFDFRLEGVTSVSADTHKYGYGAKGTSVILYRRPDLLHYQ 338 Query: 326 ---SDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIID 382 + +P F+ GA + + A+ L EG + I + + Sbjct: 339 YFIAADWPGGLYFSPTFAGSRPGALSATAWAAMLSLGEEGYLDATRRILQAADRLKAGVR 398 Query: 383 TFTSLGY 389 SL Sbjct: 399 AIPSLKI 405 >5N3U-B nrPDB Length = 208 Score = 32.1 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 20/56 (35%) Query: 243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAM 298 NNPT AA L QL E A + D Y + P A +V + Sbjct: 44 NNPTAAAIASTALVQLGEVAVPQLLTQIDDYNYGARAYSIRTLAAIADPRALDVLI 99 >5VIU-A nrPDB Length = 419 Score = 31.7 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 24/215 (11%), Positives = 58/215 (26%), Gaps = 22/215 (10%) Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 L Q E KK+ + + D + ++ + K Sbjct: 217 VPNEGFLKQSSELCKKHNVLFIADEVQTGIARTGKLIACHHEDVQPDILI----LGKALS 272 Query: 309 FTGVRLGWTVIPKKL---LYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEA 365 + + + + N + C A ++ Q L+ + Sbjct: 273 GGMYPVSAVLANNNIMDVIKPGQHGSTFGGNPLACAVAMAALDVVQDEKLSERAEKLGNL 332 Query: 366 MHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTT 425 I E T++I + + P+ S+ L++ ++ Sbjct: 333 FRSEIEKLIEKTDLITKVRGKGLLNAI-------LINDTPDSSTAWNLCLALKENGLLAK 385 Query: 426 PGSGFGPGGEGFVRVS--AFGHRENILEACRRFKQ 458 P G +R++ E +L+ + ++ Sbjct: 386 PTHG------NIIRLAPPLVITEEQLLDCVKIIEK 414 >1ULZ-A nrPDB Length = 451 Score = 31.7 bits (70), Expect = 0.67, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 40/135 (29%), Gaps = 12/135 (8%) Query: 295 EVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGA 354 E+A+ K G V + + + +A + I + N + Sbjct: 12 EIAVRIIRACKELGIPTV----AIYNEVESTARHVKLADEAYMIGTDPLDTYLNKQRIIN 67 Query: 355 LACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFA 414 LA G +A+H GF EN G G W Sbjct: 68 LA--LEVGADAIHPGYGFLAENAEF-AKMCEEAGITFIGPH-----WKVIELMGDKARSK 119 Query: 415 EILEKTHVVTTPGSG 429 E+++K V PGS Sbjct: 120 EVMKKAGVPVVPGSD 134 >4C65-A nrPDB Length = 438 Score = 31.7 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 47/157 (29%), Gaps = 26/157 (16%) Query: 121 STIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTI 180 + GY+ Y G +AK G +G + S GA L G Sbjct: 104 ALQNGYTSYRDLAGYG---CEVAKAINDGTIVGPN--VYSSGA-----ALSQTAGHGDIF 153 Query: 181 AVQDP----SYPAYVDSSVIMGQTGQFNTD----VQKYGNIEYMRCTPENGFFPDLSTVG 232 A+ SY G D V++ ++ R + Sbjct: 154 ALPAGEVLGSYGVMNPRPGYWGAGPLCIADGVEEVRRAVRLQIRRGAKVIKVMASGGVMS 213 Query: 233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSII 269 R D NP A + E+L +VE A + I+ Sbjct: 214 RDD--------NPNFAQFSPEELKVIVEEAARQNRIV 242 >5LH9-A nrPDB Length = 458 Score = 31.7 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 22/80 (27%), Gaps = 26/80 (32%) Query: 249 AATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAG 308 + +L E ++G +++ D F + Sbjct: 241 VPPADYWPRLREVCDRHGILLIADEV-------------------------VTGFGRSGC 275 Query: 309 FTGVRLGWTVIPKKLLYSDG 328 G R GW V P L + G Sbjct: 276 MLGSR-GWGVAPDILCLAKG 294 >1WA5-C nrPDB Length = 960 Score = 31.3 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 23/53 (43%) Query: 228 LSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS 280 L+ I +P+NP T E + ++ + ++ ++ DS +++ Sbjct: 596 LAQFIEIVTIMAKNPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSMMPTFLT 648 >6GIO-D nrPDB Length = 439 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 11/27 (40%) Query: 248 AAATREQLTQLVEFAKKNGSIIVYDSA 274 L L + +K+G ++V D Sbjct: 214 VVPPPAFLEALQDRCRKHGILVVVDEV 240 >5VNX-A nrPDB Length = 393 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 51/135 (37%), Gaps = 22/135 (16%) Query: 146 FYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNT 205 F GG ++ S G +++ + + G + TI + ++ + ++ T Sbjct: 96 FAGGFSDAPRALYFSTGYMANLAAVTALAGKDATI------FSDALNHASLIDGTRLSRA 149 Query: 206 DVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATRE----QLTQLVEF 261 VQ Y + + + +T +I T + + L +L+ Sbjct: 150 TVQVYPHADTATLGALLE-----ACTSQTKLIV-------TDTVFSMDGDIAPLAELLAL 197 Query: 262 AKKNGSIIVYDSAYA 276 A+++G+ +V D A+ Sbjct: 198 AERHGAWLVVDDAHG 212 >5IJW-A nrPDB Length = 279 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 55/190 (28%), Gaps = 32/190 (16%) Query: 86 LKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGA----EQGAKPLRAA 141 L P + SL IGD A + Y E +R A Sbjct: 49 LTIPQIRAHSLAIGDDLVSRGVKALVIACNTASSACLRDARERYSPVPVVEVILPAVRRA 108 Query: 142 IAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTG 201 +A T G +G+ ++ GA D ++ A D+ V Sbjct: 109 VAATRNGRIGVIGTQATIASGAYQD-------------------AFAAARDTEVFTVACP 149 Query: 202 QFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEF 261 +F V++ G+ + + D + + P L+ L++ Sbjct: 150 RFVDFVERGVTSGRQVLGLAEGYL-EPLQLAEVDTLVLGCTHYPM--------LSGLIQL 200 Query: 262 AKKNGSIIVY 271 A + +V Sbjct: 201 AMGDNVTLVS 210 >3LGA-A nrPDB Length = 253 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 19/148 (12%), Positives = 42/148 (28%), Gaps = 12/148 (8%) Query: 237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYD--------SAYAMYMSDDNPRSIF 288 +F + P G + E + A +N +D Y ++ I Sbjct: 109 LFLANIVGPEGRVVSYEIREDFAKLAWENIKWAGFDDRVTIKLKDIYEGIEEENVDHVIL 168 Query: 289 EIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASN 348 ++P E V +K G + +T +++ + + + + Sbjct: 169 DLPQPERVV---EHAAKALKPGGFFVAYTPCSNQVM-RLHEKLREFKDYFMKPRTINVLV 224 Query: 349 ISQAGALACLTPEGLEAMHKVIGFYKEN 376 Q C+ P +H + Sbjct: 225 FDQEVKKECMRPRTTALVHTGYITFARR 252 >5WGB-A nrPDB Length = 426 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 20/181 (11%), Positives = 52/181 (28%), Gaps = 20/181 (11%) Query: 102 TEPIPEVITSAMAKKAHEL--STIEGYSGYG--AEQGAKPLRAAIAKTFYGGLGIGDDDV 157 T P+ + AM + YG +E + R +A +G ++ Sbjct: 35 TTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASL----IGADPREI 90 Query: 158 FVSDGAKC----DISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNI 213 + GA I + + S + + ++ + + + Sbjct: 91 IFTSGATESNNIAIKGVARFYRSRKKHLI-----TTQTEHKCVLDSCRSLEAEGFQVTYL 145 Query: 214 EYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDS 273 + + + + T ++ + NN G ++ + ++ D+ Sbjct: 146 PVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGV---KQPIAEIGRICSSRKVYFHTDA 202 Query: 274 A 274 A Sbjct: 203 A 203 >4QGR-A nrPDB Length = 382 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 19/151 (12%), Positives = 44/151 (29%), Gaps = 20/151 (13%) Query: 132 EQGAKPLRAAIAKTFYG-GLGIGDDDVFVSDGAKCDIS--RLQVMFGSNVTIAVQDPSYP 188 +G L +A+ G +G + V + + G + V ++ Sbjct: 34 AEGRYILGPEVAEFEKKLGEYLGVEHVIACANGTDALQMPLMTRGIGPGHAVFVPSFTFA 93 Query: 189 AYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPE-----NGFFPDLSTVGRTDIIFFCSPN 243 A + ++G F N+ + + + D+ + Sbjct: 94 ATAEVVALVGAEPVFVDVDPDSYNMNVEQLEAAIAATIKEGRLEPKAIIPVDLFGLAASY 153 Query: 244 NPTGAAATREQLTQLVEFAKKNGSIIVYDSA 274 N ++ A++ G I+ D+A Sbjct: 154 N------------RITAIAEREGLFIIEDAA 172 >6IO1-A nrPDB Length = 451 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 19/172 (11%), Positives = 51/172 (29%), Gaps = 16/172 (9%) Query: 247 GAAATRE-QLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSK 305 G + + +K G +++ D ++F + V + +F+K Sbjct: 234 GVVVPPDGYWPAIAAVLRKYGILLILDEV---ITGFGRTGTLFGMQQ-YGVQPDIVTFAK 289 Query: 306 YAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEA 365 G+ G+ + + + +R+ F + + L + Sbjct: 290 -----GITSGYVPLGGVGVSDEIAETLASADRVFMHGFTYSGHPVACA--VALRNLDILL 342 Query: 366 MHKVIGFYKENTNIIIDTFTSLGYDVY----GGKNAPYVWVHFPNQSSWDVF 413 ++ + ++ L Y GK + +++S + F Sbjct: 343 AERLWENAAASGAYLLQELKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKF 394 >3U9T-A nrPDB Length = 655 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 31/114 (27%), Gaps = 6/114 (5%) Query: 314 LGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFY 373 +G + + D + S + +A G +A+H GF Sbjct: 32 IGSVAVHSDIDRHARHVAEADIAVDLGGAKPADSYLRGDRIIAAALASGAQAIHPGYGFL 91 Query: 374 KENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPG 427 EN + G G A S ++E+ V PG Sbjct: 92 SENADFAR-ACEEAGLLFLGPPAAA-----IDAMGSKSAAKALMEEAGVPLVPG 139 >4HDE-A nrPDB Length = 170 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 23/56 (41%), Gaps = 1/56 (1%) Query: 77 IARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAE 132 +A+ + + D Q +S + D PE + + + K + S +GY E Sbjct: 55 MAKLQKMAKEEKLDVQFVSFSV-DPDLDKPENLKAFIQKFTEDTSNWNLLTGYSLE 109 >3RI6-A nrPDB Length = 430 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 35/115 (30%), Gaps = 3/115 (2%) Query: 161 DGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTP 220 GA ++ M + I + + V + + G T IE Sbjct: 95 TGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFVDV 154 Query: 221 ENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275 + + + T ++F + +NP L L + G +V D+ Sbjct: 155 MDSLAVEHACDETTKLLFLETISNPQ---LQVADLEALSKVVHAKGIPLVVDTTM 206 >4ISY-A nrPDB Length = 404 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 6/67 (8%) Query: 102 TEPIPEVITSAMA--KKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFV 159 T P+ AMA ++ ++ SG A + + R IA LG +V Sbjct: 20 TTPMHPAAIEAMAAVQRTIGNASSLHTSGRSARRRIEEARELIADK----LGARPSEVIF 75 Query: 160 SDGAKCD 166 + G Sbjct: 76 TAGGTES 82 >4NZ0-A nrPDB Length = 460 Score = 29.4 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 49/156 (31%), Gaps = 30/156 (19%) Query: 259 VEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASF--------------S 304 E +K + D Y ++ D+ R I ++ A+ ++ F S Sbjct: 138 AERLEKMNNKDFSDIVYQTFLKDEL-RPIEKVQAAKTRIVDVPPFEHCILGRQLLGKFAS 196 Query: 305 KYAGFTGVRLGWTVIPKKLLYSDGFPVAKD-FNRIICTCFNGASNISQAGALACLTPE-- 361 K+ G+ LG + ++ F VA F R+ ++ + L E Sbjct: 197 KFQTQPGLELGSAIGCDPDVHWTAFGVAMQGFERVYDVDYSNFDSTHSVAMFRLLAEEFF 256 Query: 362 ------------GLEAMHKVIGFYKENTNIIIDTFT 385 LE++ Y+E +I Sbjct: 257 SEENGFDPLVKDYLESLAISKHAYEEKRYLITGGLP 292 >3RHA-A nrPDB Length = 482 Score = 28.6 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 41/145 (28%), Gaps = 11/145 (7%) Query: 98 IGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDV 157 GD T P+ E + M K L + G R +F+ L +D Sbjct: 103 TGD-TFPVNETTKAEMDKLVAILDELAAEIGPTEPWAHPKARELDTISFHHWLRQNSND- 160 Query: 158 FVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMR 217 + + + + + P++ +V+M + + + I R Sbjct: 161 ------EEACNNIGLFIAGG---MLTKPAHAFSALQAVLMAASAGSFSHLTDEDFILDKR 211 Query: 218 CTPENGFFPDLSTVGRTDIIFFCSP 242 L D + SP Sbjct: 212 VIGGMQQVSLLQAAELGDDVVLNSP 236 >1FGS-A nrPDB Length = 428 Score = 28.2 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 25/80 (31%), Gaps = 8/80 (10%) Query: 208 QKYGNIEYMRCTPEN--------GFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLV 259 + Y TP+N + L + T +I +NP G L QL Sbjct: 273 KVYAKQTEWPLTPQNIRQGLAASHWPARLEKISDTPLIVIDGAHNPDGINGLITALKQLF 332 Query: 260 EFAKKNGSIIVYDSAYAMYM 279 + I+ D YA Sbjct: 333 SQPITVIAGILADKDYAAMA 352 >5O9Z-R nrPDB Length = 557 Score = 28.2 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 8/59 (13%) Query: 49 PQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISL--GIGDTTEPI 105 P+ KIE+KT++ RN LF A R+ L A V+ L DT P Sbjct: 202 PENKIEFKTRLGRNVY------RMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPT 254 >4BA4-A nrPDB Length = 459 Score = 27.8 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 3/26 (11%), Positives = 8/26 (30%) Query: 249 AATREQLTQLVEFAKKNGSIIVYDSA 274 ++ +K ++V D Sbjct: 236 VPPATYWPEIERICRKYDVLLVADEV 261 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.125 0.316 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,732,900 Number of Sequences: 36641 Number of extensions: 592274 Number of successful extensions: 2753 Number of sequences better than 10.0: 210 Number of HSP's better than 10.0 without gapping: 193 Number of HSP's successfully gapped in prelim test: 128 Number of HSP's that attempted gapping in prelim test: 2033 Number of HSP's gapped (non-prelim): 351 length of query: 461 length of database: 10,336,785 effective HSP length: 100 effective length of query: 361 effective length of database: 6,672,685 effective search space: 2408839285 effective search space used: 2408839285 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.2 bits)