BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q93LQ6 (699 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1R6V-A nrPDB 1361 0.0 3VYV-A nrPDB 150 2e-36 3WHI-A nrPDB 149 4e-36 1DBI-A nrPDB 145 6e-35 1BH6-A nrPDB 140 2e-33 2E1P-A nrPDB 131 1e-30 1Y3F-E nrPDB 130 1e-30 3A3N-A nrPDB 130 3e-30 1NDQ-A nrPDB 129 5e-30 1SCN-E nrPDB 125 6e-29 3TEC-E nrPDB 119 3e-27 1GNV-A nrPDB 117 2e-26 6F9M-A nrPDB 115 9e-26 5FFN-A nrPDB 112 5e-25 5YL7-A nrPDB 110 2e-24 2IXT-A nrPDB 109 4e-24 3LPA-A nrPDB 108 8e-24 2WV7-A nrPDB 106 3e-23 3TI9-A nrPDB 102 7e-22 1V6C-A nrPDB 99 5e-21 3I30-X nrPDB 96 8e-20 4LVN-A nrPDB 89 5e-18 3ZXX-A nrPDB 88 1e-17 3VV3-A nrPDB 87 3e-17 2GKO-A nrPDB 87 3e-17 3F7M-A nrPDB 86 5e-17 4TR2-A nrPDB 86 7e-17 1SH7-A nrPDB 85 9e-17 2B6N-A nrPDB 83 5e-16 5Z6O-A nrPDB 82 1e-15 4H6W-A nrPDB 81 1e-15 5WSL-A nrPDB 80 4e-15 3AFG-A nrPDB 80 4e-15 4MZD-A nrPDB 77 3e-14 3QFH-A nrPDB 75 1e-13 3F7O-A nrPDB 70 3e-12 4KB5-A nrPDB 70 3e-12 4DZT-A nrPDB 70 4e-12 4ZOQ-I nrPDB 69 6e-12 4HVL-A nrPDB 64 2e-10 5FAX-A nrPDB 62 1e-09 4KG7-A nrPDB 59 7e-09 1WMD-A nrPDB 59 1e-08 2W2P-A nrPDB 58 1e-08 5VLH-A nrPDB 57 3e-08 6F5G-A nrPDB 55 7e-08 4K8R-B nrPDB 54 2e-07 1XF1-A nrPDB 54 2e-07 2ID4-A nrPDB 50 4e-06 4H6X-A nrPDB 49 5e-06 3HJR-A nrPDB 46 7e-05 5MIM-A nrPDB 43 5e-04 4I0W-B nrPDB 38 0.016 2ZY2-A nrPDB 37 0.027 4YN3-A nrPDB 37 0.039 5C3R-A nrPDB 32 0.86 1OFM-A nrPDB 31 1.9 4REV-A nrPDB 30 4.5 2UXV-A nrPDB 29 7.0 >1R6V-A nrPDB Length = 671 Score = 1361 bits (3523), Expect = 0.0, Method: Compositional matrix adjust. Identities = 670/671 (99%), Positives = 670/671 (99%) Query: 29 SKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELP 88 SKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELP Sbjct: 1 SKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELP 60 Query: 89 QIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGL 148 QIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGL Sbjct: 61 QIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGL 120 Query: 149 NSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY 208 NSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY Sbjct: 121 NSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY 180 Query: 209 RPAFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGG 268 RPAFDEELPAGTDSSYGGS GTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGG Sbjct: 181 RPAFDEELPAGTDSSYGGSAGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGG 240 Query: 269 NGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS 328 NGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS Sbjct: 241 NGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS 300 Query: 329 DSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYE 388 DSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYE Sbjct: 301 DSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYE 360 Query: 389 GHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN 448 GHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN Sbjct: 361 GHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN 420 Query: 449 GWDHDTGYGLVKLDAALQGPLPTQGGVEEFQVVVTDAKGNFGVPTVFVSMMRDNGSCYYA 508 GWDHDTGYGLVKLDAALQGPLPTQGGVEEFQVVVTDAKGNFGVPTVFVSMMRDNGSCYYA Sbjct: 421 GWDHDTGYGLVKLDAALQGPLPTQGGVEEFQVVVTDAKGNFGVPTVFVSMMRDNGSCYYA 480 Query: 509 KTGPDGIARFPHIDSGTYDIFVGGPDHWDRALAPYDGESIPGGYAIALRMAEERQASFVG 568 KTGPDGIARFPHIDSGTYDIFVGGPDHWDRALAPYDGESIPGGYAIALRMAEERQASFVG Sbjct: 481 KTGPDGIARFPHIDSGTYDIFVGGPDHWDRALAPYDGESIPGGYAIALRMAEERQASFVG 540 Query: 569 FGVSPDATQLNVNFNSTLQVKFSTNLSTLKDPQFVVVDPLLRGVYGRVAYARNQTYDLSL 628 FGVSPDATQLNVNFNSTLQVKFSTNLSTLKDPQFVVVDPLLRGVYGRVAYARNQTYDLSL Sbjct: 541 FGVSPDATQLNVNFNSTLQVKFSTNLSTLKDPQFVVVDPLLRGVYGRVAYARNQTYDLSL 600 Query: 629 LSGQISFGIQTLLPAATDITIQGTVTLNGEDIPVYGVLKAGTTWTIIDDFGGLNLGTDSQ 688 LSGQISFGIQTLLPAATDITIQGTVTLNGEDIPVYGVLKAGTTWTIIDDFGGLNLGTDSQ Sbjct: 601 LSGQISFGIQTLLPAATDITIQGTVTLNGEDIPVYGVLKAGTTWTIIDDFGGLNLGTDSQ 660 Query: 689 PIYVWWTIFGQ 699 PIYVWWTIFGQ Sbjct: 661 PIYVWWTIFGQ 671 >3VYV-A nrPDB Length = 275 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 109/290 (37%), Positives = 152/290 (52%), Gaps = 39/290 (13%) Query: 180 SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK 239 +G+N+ VAV+D+G+D +HPDL + A + P+ G+ SHGTHVAGTIAA Sbjct: 22 TGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSETNPYQDGS------SHGTHVAGTIAAL 75 Query: 240 KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGW 299 + G++GVAP A + + + D G Y ++ GI WA + V+N S GG Sbjct: 76 NNSIGVLGVAPSASLYAVKVLDS---TGSGQY---SWIINGIEWAISNNMDVINMSLGGP 129 Query: 300 GYSYTMKEAFDYAMEHGVVMVVSAGN---NTSDSHHQYPAGYPGVIQVAALDYYGGTFRV 356 S +K D A+ G+V+ +AGN + S S YPA YP I V A++ + + Sbjct: 130 TGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVN---SSNQR 186 Query: 357 AGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVT 416 A FSS + V APGV+I ST+PG GTY Y GTSMA PHV Sbjct: 187 ASFSSVGSELDVMAPGVSIQSTLPG------------------GTYGAYNGTSMATPHVA 228 Query: 417 GVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 G A++L K P Q+R LE+TA + GN + + G GL+ + AA Q Sbjct: 229 GAAALILSKHPTWTNAQVRDRLESTA-TYLGNSFYY--GKGLINVQAAAQ 275 >3WHI-A nrPDB Length = 365 Score = 149 bits (376), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 106/290 (36%), Positives = 150/290 (51%), Gaps = 39/290 (13%) Query: 180 SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK 239 +G+N+ VAV+D+G+D +HPDL + A + P+ G+ SHGTHVAGTIAA Sbjct: 112 TGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSETNPYQDGS------SHGTHVAGTIAAL 165 Query: 240 KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGW 299 + G++GV+P A + + + D G Y ++ GI WA + V+N S GG Sbjct: 166 NNSIGVLGVSPSASLYAVKVLDS---TGSGQY---SWIINGIEWAISNNMDVINMSLGGP 219 Query: 300 GYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ---YPAGYPGVIQVAALDYYGGTFRV 356 S +K D A+ G+V+ +AGN S YPA YP I V A++ + + Sbjct: 220 TGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVN---SSNQR 276 Query: 357 AGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVT 416 A FSS + V APGV+I ST+PG GTY Y GT+MA PHV Sbjct: 277 ASFSSAGSELDVMAPGVSIQSTLPG------------------GTYGAYNGTAMATPHVA 318 Query: 417 GVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 G A++L K P Q+R LE+TA + GN + + G GL+ + AA Q Sbjct: 319 GAAALILSKHPTWTNAQVRDRLESTA-TYLGNSFYY--GKGLINVQAAAQ 365 >1DBI-A nrPDB Length = 280 Score = 145 bits (366), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 113/315 (35%), Positives = 161/315 (51%), Gaps = 54/315 (17%) Query: 136 PNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDG 195 PN Y+ + G +T DY +++ G E +AV+DTGVD Sbjct: 3 PNDTYYQGYQYGPQNTYTDYAWDVTKGSSGQE------------------IAVIDTGVDY 44 Query: 196 THPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK-KDGKGIVGVAPGAKI 254 THPDL+G+VI GY ++ P ++ HGTHVAG AA+ + GI G+AP +I Sbjct: 45 THPDLDGKVIKGYDFVDNDYDPMDLNN-----HGTHVAGIAAAETNNATGIAGMAPNTRI 99 Query: 255 MPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAME 314 + + D G+G + D +A II+A D GA+V+N S G ++ T++ A +YA Sbjct: 100 LAVRALDR----NGSGTLSD--IADAIIYAADSGAEVINLSLGCDCHTTTLENAVNYAWN 153 Query: 315 HGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVT 374 G V+V +AGNN S + + PA Y VI V A+D Y R+A FS+ V V APGV Sbjct: 154 KGSVVVAAAGNNGSSTTFE-PASYENVIAVGAVDQYD---RLASFSNYGTWVDVVAPGVD 209 Query: 375 ILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQI 434 I+ST+ G Y Y GTSMA+PHV G+ A+L + N +I Sbjct: 210 IVSTITGN------------------RYAYMSGTSMASPHVAGLAALLASQGRN--NIEI 249 Query: 435 RKLLENTAFDFNGNG 449 R+ +E TA +G G Sbjct: 250 RQAIEQTADKISGTG 264 >1BH6-A nrPDB Length = 274 Score = 140 bits (352), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 103/289 (35%), Positives = 143/289 (49%), Gaps = 40/289 (13%) Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK 240 G N+ V ++DTG+ +H DL +V+ G +F TD G HGTHVAGT+AA Sbjct: 23 GANVKVGIIDTGIASSHTDL--KVVGG--ASFVSGESYNTD---GNGHGTHVAGTVAALD 75 Query: 241 DGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWG 300 + G++GVAP + I + + G Y + +GI WAT +G V+N S GG Sbjct: 76 NTTGVLGVAPNVSLYAIKVLNSS---GSGSY---SAIVSGIEWATQNGLDVINMSLGGPS 129 Query: 301 YSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ---YPAGYPGVIQVAALDYYGGTFRVA 357 S +K+A D A G+V+V +AGN+ + YPA Y VI V A+D A Sbjct: 130 GSTALKQAVDKAYASGIVVVAAAGNSGNSGSQNTIGYPAKYDSVIAVGAVD---SNKNRA 186 Query: 358 GFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTG 417 FSS + V APGV++ ST P TY GTSMA+PHV G Sbjct: 187 SFSSVGSELEVMAPGVSVYSTYPSN------------------TYTSLNGTSMASPHVAG 228 Query: 418 VVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 A++L K+P Q+R L +TA + G G GL+ ++AA Q Sbjct: 229 AAALILSKYPTLSASQVRNRLSSTATNL---GDSFYYGKGLINVEAAAQ 274 >2E1P-A nrPDB Length = 398 Score = 131 bits (329), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 116/340 (34%), Positives = 162/340 (47%), Gaps = 64/340 (18%) Query: 164 WGLEAIGVTQQLWE--EASGTNIIVAVVDTGVDGTHPDLEGQV---IAGYRPAFDEELPA 218 WG+E + +W + S + I VAV+DTGVD HPDL + ++ R +L Sbjct: 88 WGIERVK-APSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKL-- 144 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFD--------------DPA 264 D + HGTHV GTIAA + G+VGVAPG +I + + D + A Sbjct: 145 -RDCADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQA 203 Query: 265 LVGGNGYVGDDYVAAGIIWA--TDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVS 322 ++G +G D GII D A+V++ S GG + + A G+V+V + Sbjct: 204 ILGPDGVADKD--GDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVAA 261 Query: 323 AGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGE 382 +GN + S YPA YP VI V A+D +A FS+R VS APGV ILST P + Sbjct: 262 SGNEGAPS-PSYPAAYPEVIAVGAID---SNDNIASFSNRQPEVS--APGVDILSTYPDD 315 Query: 383 DSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVL----LQKFPNAKPW------ 432 +Y+ GT+MA PHV+GVVA++ QK+ P Sbjct: 316 ------------------SYETLMGTAMATPHVSGVVALIQAAYYQKYGKILPVGTFDDI 357 Query: 433 ---QIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPL 469 +R +L TA D GWD D GYG+V+ A+Q L Sbjct: 358 SKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAAL 397 >1Y3F-E nrPDB Length = 281 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 97/265 (36%), Positives = 134/265 (50%), Gaps = 36/265 (13%) Query: 180 SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK 239 +G+N+ VAV+D+G+D +HPDL+ +AG E D++ SHGTHVAGT+AA Sbjct: 22 TGSNVKVAVIDSGIDSSHPDLK---VAGGASMVPSETNPFQDNN---SHGTHVAGTVAAL 75 Query: 240 KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGW 299 + G++GVAP A + + + G +G ++ GI WA + V+N S GG Sbjct: 76 NNSIGVLGVAPSASLYAVKVL------GADGSGQYSWIINGIEWAIANNMDVINMSLGGP 129 Query: 300 GYSYTMKEAFD---YAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRV 356 S +K A D + V + G + S S YP YP VI V A+D + + Sbjct: 130 SGSAALKAAVDKAVASGVVVVAAAGNEGTSGSSSTVGYPGKYPSVIAVGAVD---SSNQR 186 Query: 357 AGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVT 416 A FSS + V APGV+I ST+PG Y Y GTSMA+PHV Sbjct: 187 ASFSSVGPELDVMAPGVSIQSTLPGNK------------------YGAYNGTSMASPHVA 228 Query: 417 GVVAVLLQKFPNAKPWQIRKLLENT 441 G A++L K PN Q+R LENT Sbjct: 229 GAAALILSKHPNWTNTQVRSSLENT 253 >3A3N-A nrPDB Length = 329 Score = 130 bits (326), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 116/340 (34%), Positives = 162/340 (47%), Gaps = 64/340 (18%) Query: 164 WGLEAIGVTQQLWE--EASGTNIIVAVVDTGVDGTHPDLEGQV---IAGYRPAFDEELPA 218 WG+E + +W + S + I VAV+DTGVD HPDL + ++ R +L Sbjct: 19 WGIERVK-APSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKL-- 75 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFD--------------DPA 264 D + HGTHV GTIAA + G+VGVAPG +I + + D + A Sbjct: 76 -RDCADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQA 134 Query: 265 LVGGNGYVGDDYVAAGIIWA--TDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVS 322 ++G +G D GII D A+V++ S GG + + A G+V+V + Sbjct: 135 ILGPDGVADKD--GDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVAA 192 Query: 323 AGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGE 382 +GN + S YPA YP VI V A+D +A FS+R VS APGV ILST P + Sbjct: 193 SGNEGAPS-PSYPAAYPEVIAVGAID---SNDNIASFSNRQPEVS--APGVDILSTYPDD 246 Query: 383 DSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVL----LQKFPNAKPW------ 432 +Y+ GT+MA PHV+GVVA++ QK+ P Sbjct: 247 ------------------SYETLMGTAMATPHVSGVVALIQAAYYQKYGKILPVGTFDDI 288 Query: 433 ---QIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPL 469 +R +L TA D GWD D GYG+V+ A+Q L Sbjct: 289 SKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAAL 328 >1NDQ-A nrPDB Length = 269 Score = 129 bits (323), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 103/303 (33%), Positives = 145/303 (47%), Gaps = 39/303 (12%) Query: 164 WGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSS 223 WG+ + +G+ + VAV+DTG+ THPDL + A + P P+ D Sbjct: 6 WGISRVQAPAAHNRGLTGSGVKVAVLDTGIS-THPDLNIRGGASFVPGE----PSTQD-- 58 Query: 224 YGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIW 283 G HGTHVAGTIAA + G++GVAP A++ + + +A G+ W Sbjct: 59 -GNGHGTHVAGTIAALNNSIGVLGVAPSAELYAVKVLGASG------SGSVSSIAQGLEW 111 Query: 284 ATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQ 343 A ++G V N S G S T+++A + A GV++V ++GN+ + S YPA Y + Sbjct: 112 AGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGAGSI-SYPARYANAMA 170 Query: 344 VAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYD 403 V A D A FS G+ + APGV + ST PG TY Sbjct: 171 VGATDQ---NNNRASFSQYGAGLDIVAPGVNVQSTYPGS------------------TYA 209 Query: 404 YYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDA 463 GTSMA PHV G A++ QK P+ QIR L+NTA G + G GLV +A Sbjct: 210 SLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSL---GSTNLYGSGLVNAEA 266 Query: 464 ALQ 466 A + Sbjct: 267 ATR 269 >1SCN-E nrPDB Length = 276 Score = 125 bits (314), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 105/291 (36%), Positives = 139/291 (47%), Gaps = 40/291 (13%) Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK 240 G N+ VAV+DTG+ +HPDL V+ G +F TD G HGTHVAGT+AA Sbjct: 23 GANVKVAVLDTGIQASHPDLN--VVGG--ASFVAGEAYNTD---GNGHGTHVAGTVAALD 75 Query: 241 DGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWG 300 + G++GVAP + + + + + +GI WAT +G V+N S GG Sbjct: 76 NTTGVLGVAPSVSLYAVKVLNSSGS------GSYSGIVSGIEWATTNGMDVINMSLGGAS 129 Query: 301 YSYTMKEAFDYA---MEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVA 357 S MK+A D A V ++GN+ S + YPA Y VI V A+D A Sbjct: 130 GSTAMKQAVDNAYARGVVVVAAAGNSGNSGSTNTIGYPAKYDSVIAVGAVD---SNSNRA 186 Query: 358 GFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTG 417 FSS + V APG + ST P TN TY GTSMA+PHV G Sbjct: 187 SFSSVGAELEVMAPGAGVYSTYP----------------TN--TYATLNGTSMASPHVAG 228 Query: 418 VVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGP 468 A++L K PN Q+R L +TA G G GL+ ++AA Q P Sbjct: 229 AAALILSKHPNLSASQVRNRLSSTATYL---GSSFYYGKGLINVEAAAQAP 276 >3TEC-E nrPDB Length = 279 Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 100/277 (36%), Positives = 134/277 (48%), Gaps = 36/277 (12%) Query: 174 QLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVA 233 Q W+ A G+ +A+VDTGV HPDL G+V+ G+ ++ P G HGTH A Sbjct: 22 QAWDIAEGSGAKIAIVDTGVQSNHPDLAGKVVGGWDFVDNDSTPQN-----GNGHGTHCA 76 Query: 234 GTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVM 292 G AA + GI G AP A I+ + + D+ G+G VA GI +A D GAKV+ Sbjct: 77 GIAAAVTNNSTGIAGTAPKASILAVRVLDNS----GSGTW--TAVANGITYAADQGAKVI 130 Query: 293 NHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGG 352 + S GG + +++A +YA G V VV+A N ++ YPA Y I VA+ D Sbjct: 131 SLSLGGTVGNSGLQQAVNYAWNKGSV-VVAAAGNAGNTAPNYPAYYSNAIAVASTDQ--- 186 Query: 353 TFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAA 412 + FS+ V V APG I ST P TY GTSMA Sbjct: 187 NDNKSSFSTYGSVVDVAAPGSWIYSTYPTS------------------TYASLSGTSMAT 228 Query: 413 PHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNG 449 PHV GV +L + +A IR +ENTA +G G Sbjct: 229 PHVAGVAGLLASQGRSAS--NIRAAIENTADKISGTG 263 >1GNV-A nrPDB Length = 266 Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 100/290 (34%), Positives = 136/290 (46%), Gaps = 48/290 (16%) Query: 180 SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK 239 +G+N+ VAV+D+G+D +HPDL +AG E D++ SHGTHVAGT+ A Sbjct: 22 TGSNVKVAVIDSGIDSSHPDLN---VAGGASFVPSETNPFQDNN---SHGTHVAGTVLA- 74 Query: 240 KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGW 299 VAP A + + + G +G ++ GI WA + V+N S GG Sbjct: 75 --------VAPSASLYAVKVL------GADGSGQYSWIINGIEWAIANNMDVINMSLGGP 120 Query: 300 GYSYTMKEAFD---YAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRV 356 S +K A D + V + G + S S YP YP VI V A+D + + Sbjct: 121 SGSAALKAAVDKAVASGVVVVAAAGNEGTSGSSSTVGYPGKYPSVIAVGAVD---SSNQR 177 Query: 357 AGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVT 416 A FSS + V APGV+I ST+PG Y GTSMA+PHV Sbjct: 178 ASFSSVGPELDVMAPGVSICSTLPGNK------------------YGAKSGTSMASPHVA 219 Query: 417 GVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 G A++L K PN Q+R LENT G G GL+ ++AA Q Sbjct: 220 GAAALILSKHPNWTNTQVRSSLENTTTKL---GDSFYYGKGLINVEAAAQ 266 >6F9M-A nrPDB Length = 330 Score = 115 bits (287), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 92/261 (35%), Positives = 131/261 (50%), Gaps = 40/261 (15%) Query: 174 QLWEEAS-GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHV 232 +LWE A G +VAV+DTG HPDL ++ G D+ Y G HGTHV Sbjct: 32 ELWESAEHGKGNVVAVLDTGCQTDHPDLTARIAGGRNFTHDDGGDPERFEDYNG-HGTHV 90 Query: 233 AGTIAAK-KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATD----H 287 AGT+AA +D +G+VGVAP A ++ + + D G Y G + AGI +A D Sbjct: 91 AGTVAASLRDEEGVVGVAPLADLLVVKVLDKE---GSGSYEG---IIAGIHYAIDWRGPE 144 Query: 288 GAK--VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ----YPAGYPGV 341 G K V++ S GG + EA A++ G+ ++ +AGN D+H YP Y V Sbjct: 145 GQKTTVISMSLGGPEDHPELYEAVKRAVDAGIPVICAAGNEGDDAHDTDEFAYPGAYGEV 204 Query: 342 IQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGT 401 IQV A+D+ R+A FS+ ++ + + APG+ I ST G Sbjct: 205 IQVGAVDF---DRRIAPFSNTNNEIDLVAPGINIYSTYL------------------EGK 243 Query: 402 YDYYQGTSMAAPHVTGVVAVL 422 Y GTSMA PHV+G +A++ Sbjct: 244 YASLSGTSMATPHVSGALALI 264 >5FFN-A nrPDB Length = 311 Score = 112 bits (281), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 107/327 (32%), Positives = 154/327 (47%), Gaps = 54/327 (16%) Query: 164 WGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSS 223 WG+++I Q + + G+ I VAV+DTGV +H DL G L G+ + Sbjct: 9 WGIKSIYNDQSITKTTGGSGIKVAVLDTGVYTSHLDLAGSAEQCKDFTQSNPLVDGSCTD 68 Query: 224 YGGSHGTHVAGTIAAK--KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 G HGTHVAGT+ A +G+G+ GVAP AK+ + D G+GY D +AA I Sbjct: 69 RQG-HGTHVAGTVLAHGGSNGQGVYGVAPQAKLWAYKVLGD----NGSGY--SDDIAAAI 121 Query: 282 IWATDHGAK-----VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH-QYP 335 D ++ V+N S G + A DYA GV++V +AGN+ S S+ +P Sbjct: 122 RHVADEASRTGSKVVINMSLGSSAKDSLIASAVDYAYGKGVLIVAAAGNSGSGSNTIGFP 181 Query: 336 AGYPGVIQVAALD--YYGGTFRVAGFSSRSD------------GVSVGAPGVTILSTVPG 381 G + VAAL+ GT+RVA FSSR + + V APG ++ ST Sbjct: 182 GGLVNAVAVAALENVQQNGTYRVADFSSRGNPATAGDYIIQERDIEVSAPGASVESTW-- 239 Query: 382 EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENT 441 Y G Y+ GTSMA PHV G+ A + + Q+R L+N Sbjct: 240 -----YT-----------GGYNTISGTSMATPHVAGLAAKIWSANTSLSHSQLRTELQNR 283 Query: 442 A--FDFN-----GNGWDHDTGYGLVKL 461 A +D G G D+ +G+G ++ Sbjct: 284 AKVYDIKGGIGAGTGDDYASGFGYPRV 310 >5YL7-A nrPDB Length = 347 Score = 110 bits (276), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 101/305 (33%), Positives = 149/305 (48%), Gaps = 49/305 (16%) Query: 176 WEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYR-------------PAFDEELP----- 217 W+ A+G+ ++VAV+DTG H DL ++ GY D P Sbjct: 27 WDTATGSGVVVAVLDTGYR-PHADLNANILPGYDMISNLSVANDGGGRDSDARDPGDAVA 85 Query: 218 ---AGTDSSYGGS-HGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYV 272 GT+ + S HGTHVAGT+AA +G+G+ GVA AK++P+ + G G + Sbjct: 86 ANECGTNGAQNSSWHGTHVAGTVAAVTNNGEGVAGVAYNAKVVPVRVL------GKCGGL 139 Query: 273 GDDYVAAGIIWAT----------DHGAKVMN-HSWGGWGYSYTMKEAFDYAMEHGVVMVV 321 D +A GIIWA+ + A V+N G S T + A + A +G V+V+ Sbjct: 140 TSD-IADGIIWASGGSVSGIPANSNPADVINMSLGGSGSCSSTTQNAINTARSNGTVVVI 198 Query: 322 SAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPG 381 +AGN+ +S + P GV+ VA++ GG + + S D V APG + Sbjct: 199 AAGNDNDNSANYNPGNCNGVVNVASVGRNGGRAYYSNYGSNID---VAAPG---GAQSFA 252 Query: 382 EDSIG-YEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLEN 440 DS G +N + +Y Y QGTSMAAPHV GV A++ Q P+A P +I +L++ Sbjct: 253 NDSEGVLSTYNSGSSTPSSDSYGYSQGTSMAAPHVAGVAALIKQAKPDATPDEIESILKS 312 Query: 441 TAFDF 445 T F Sbjct: 313 TTRSF 317 >2IXT-A nrPDB Length = 310 Score = 109 bits (273), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 106/327 (32%), Positives = 149/327 (45%), Gaps = 54/327 (16%) Query: 164 WGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSS 223 WG++AI L G+ I +AV+DTGV+ +HPDL V + P + Sbjct: 8 WGIKAIYNNDTLTSTTGGSGINIAVLDTGVNTSHPDLVNNV-EQCKDFTGATTPINNSCT 66 Query: 224 YGGSHGTHVAGTIAAK--KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 HGTHVAGT A D GI GVAP A + + D G+GY D +AA I Sbjct: 67 DRNGHGTHVAGTALADGGSDQAGIYGVAPDADLWAYKVLLDS----GSGYSDD--IAAAI 120 Query: 282 IWATDH----GAK-VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNT-SDSHHQYP 335 A D G K +++ S G + + A +YA GV++V +AGN+ S YP Sbjct: 121 RHAADQATATGTKTIISMSLGSSANNSLISSAVNYAYSKGVLIVAAAGNSGYSQGTIGYP 180 Query: 336 AGYPGVIQVAALD--YYGGTFRVAGFSSR------------SDGVSVGAPGVTILSTVPG 381 P I VAAL+ GT+RVA +SSR + + APG ++ ST Sbjct: 181 GALPNAIAVAALENVQQNGTYRVADYSSRGYISTAGDYVIQEGDIEISAPGSSVYSTW-- 238 Query: 382 EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENT 441 NGG Y+ GTSMA PHV+G+ A + + P+ Q+R L+ Sbjct: 239 ---------------YNGG-YNTISGTSMATPHVSGLAAKIWAENPSLSNTQLRSNLQER 282 Query: 442 A--FDFNGN-----GWDHDTGYGLVKL 461 A D G G D+ +G+G ++ Sbjct: 283 AKSVDIKGGYGAAIGDDYASGFGFARV 309 >3LPA-A nrPDB Length = 340 Score = 108 bits (270), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 114/343 (33%), Positives = 162/343 (47%), Gaps = 73/343 (21%) Query: 174 QLWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGY--------------RPA------- 211 ++W+ +G N++VAVVDTG+ H DL V+ GY R A Sbjct: 23 KVWDMGFTGQNVVVAVVDTGI-LHHRDLNANVLPGYDFISNSQISLDGDGRDADPFDEGD 81 Query: 212 -FDEELPAG--------TDSSYGGSHGTHVAGTIAAKKDGK-GIVGVAPGAKIMPIVIFD 261 FD G +DSS+ HG+HVAGTIAA + + G+ GVA GAK++P+ Sbjct: 82 WFDNWACGGYPDPRKERSDSSW---HGSHVAGTIAAVTNNRIGVAGVAYGAKVVPV---- 134 Query: 262 DPALVGGNGYVGDDYVAAGIIWA----------TDHGAKVMNHSWGGWG-YSYTMKEAFD 310 AL GY D ++ G+ WA + AKV+N S G G SY + D Sbjct: 135 -RALGRCGGY--DSDISDGLYWAAGGRIAGIPENRNPAKVINMSLGSDGQCSYNAQTMID 191 Query: 311 YAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGA 370 A G ++VV+AGN ++ + +P V+ V A G R A FS+ V + A Sbjct: 192 RATRLGALVVVAAGNENQNASNTWPTSCNNVLSVGATTSRG--IR-ASFSNYGVDVDLAA 248 Query: 371 PGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKF---- 426 PG ILSTV DS P ++ Y + GTSMA PHV+GV A+++ Sbjct: 249 PGQDILSTV---DS------GTRRPVSD--AYSFMAGTSMATPHVSGVAALVISAANSVN 297 Query: 427 PNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPL 469 N P +++ +L +T FNG D G G+V +AA+ L Sbjct: 298 KNLTPAELKDVLVSTTSPFNGR-LDRALGSGIVDAEAAVNSVL 339 >2WV7-A nrPDB Length = 329 Score = 106 bits (265), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 94/285 (32%), Positives = 137/285 (48%), Gaps = 46/285 (16%) Query: 159 LSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFD---EE 215 LS G+E + A G I+ V+DTG HPDL ++I G D +E Sbjct: 18 LSEVPMGVEIVEAPAVWRASAKGAGQIIGVIDTGCQVDHPDLAERIIGGVNLTTDYGGDE 77 Query: 216 LPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVG-GNGYVGD 274 T+ S HGTHVAGT+AA + G G+VGVAP A + I AL G G+G +G Sbjct: 78 ----TNFSDNNGHGTHVAGTVAAAETGSGVVGVAPKADLFII-----KALSGDGSGEMG- 127 Query: 275 DYVAAGIIWATD------HGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGN--- 325 ++A I +A D +++ S GG S + +A YA+ + V +V +AGN Sbjct: 128 -WIAKAIRYAVDWRGPKGEQMRIITMSLGGPTDSEELHDAVKYAVSNNVSVVCAAGNEGD 186 Query: 326 -NTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDS 384 + YPA Y VI V A+D+ R++ F++ ++ + + APGV I ST DS Sbjct: 187 GREDTNEFAYPAAYNEVIAVGAVDF---DLRLSDFTNTNEEIDIVAPGVGIKSTYL--DS 241 Query: 385 IGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNA 429 Y GT+MAAPHV G +A+++ +A Sbjct: 242 ----------------GYAELSGTAMAAPHVAGALALIINLAEDA 270 >3TI9-A nrPDB Length = 352 Score = 102 bits (253), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 104/343 (30%), Positives = 156/343 (45%), Gaps = 67/343 (19%) Query: 174 QLWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGY-----------------RPA---- 211 ++W+ +G ++V+VVDTG+ H DL G ++ GY PA Sbjct: 24 KVWDRGFTGQGVVVSVVDTGIL-DHVDLNGNMLPGYDFISSAPKARDGDQRDNNPADEGD 82 Query: 212 -FDEELPAG-----TDSSYGGSHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPA 264 FD G + + HG+HVAGTIAA +G G+ GVA GAK++P+ + Sbjct: 83 WFDNWDCGGYPDPRREKRFSTWHGSHVAGTIAAVTNNGVGVAGVAYGAKVIPVRVLGKCG 142 Query: 265 LVGGNGYVGDDYVAAGIIWA----------TDHGAKVMNHSWGGWG-YSYTMKEAFDYAM 313 GY D + G+ W+ + A+V+N S GG G S + + D Sbjct: 143 -----GY--DSDITDGMYWSAGGHIDGVPDNQNPAQVINMSLGGDGDCSQSSQRIIDKTT 195 Query: 314 EHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGV 373 G ++V++AGN D+ +P+ V+ V A G + A FS+ V + APG Sbjct: 196 NLGALIVIAAGNENQDASRTWPSSCNNVLSVGATTPKG---KRAPFSNYGARVHLAAPGT 252 Query: 374 TILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKF----PNA 429 ILST+ +G G P + +Y GTSMAAPHV+GV A+++ Sbjct: 253 NILSTI----DVGQAG-----PVRS--SYGMKAGTSMAAPHVSGVAALVISAANSIGKTL 301 Query: 430 KPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLPTQ 472 P ++ +L T FNG D G G+V +AA+ L Q Sbjct: 302 TPSELSDILVRTTSRFNGR-LDRGLGSGIVDANAAVNAVLGDQ 343 >1V6C-A nrPDB Length = 441 Score = 99.4 bits (246), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 77/222 (34%), Positives = 111/222 (50%), Gaps = 24/222 (10%) Query: 164 WGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSS 223 WG +G T + ++ N + ++D+G D +H DL + G + GT + Sbjct: 6 WGQTFVGAT--VLSDSQAGNRTICIIDSGYDRSHNDLNANNVTGTNNS-------GTGNW 56 Query: 224 Y----GGSHGTHVAGTIAAKKDGKGIVGVAP--GAKIMPIVIFDDPALVGGNGYVGDDYV 277 Y +HGTHVAGTIAA + +G+VGV P A I + +F++ G GY V Sbjct: 57 YQPGNNNAHGTHVAGTIAAIANNEGVVGVMPNQNANIHIVKVFNE----AGWGY-SSSLV 111 Query: 278 AAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAG 337 AA GA V+ S GG G + T + A + +GV+++ +AG N DS + YPA Sbjct: 112 AAIDTCVNSGGANVVTMSLGGSGSTTTERNALNTHYNNGVLLIAAAG-NAGDSSYSYPAS 170 Query: 338 YPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTV 379 Y V+ VAA+D A FS +D V + PG ILSTV Sbjct: 171 YDSVMSVAAVD---SNLDHAAFSQYTDQVEISGPGEAILSTV 209 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 30/74 (40%), Positives = 40/74 (54%), Gaps = 7/74 (9%) Query: 402 YDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVK- 460 Y+YY GTSMA PHV+GV ++ P Q+R L TA D + G D+ TGYG++ Sbjct: 362 YEYYNGTSMATPHVSGVATLVWSYHPECSASQVRAALNATADDLSVAGRDNQTGYGMINA 421 Query: 461 ------LDAALQGP 468 LD + GP Sbjct: 422 VAAKAYLDESCTGP 435 >3I30-X nrPDB Length = 279 Score = 95.5 bits (236), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 84/276 (30%), Positives = 126/276 (45%), Gaps = 53/276 (19%) Query: 160 SNELWGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEG--QVIAGYRPAF 212 +N WGL I G + ++E++G V V+DTG++ +HP+ EG Q++ Y + Sbjct: 4 TNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQMVKTYYYSS 63 Query: 213 DEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGY- 271 + G HGTH AGT+ ++ GVA ++ + + DD G+G Sbjct: 64 RD----------GNGHGTHCAGTVGSR-----TYGVAKKTQLFGVKVLDD----NGSGQY 104 Query: 272 ----VGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNT 327 G D+VA+ V + S GG GYS ++ A GV++ V+AGNN Sbjct: 105 STIIAGMDFVASDKNNRNCPKGVVASLSLGG-GYSSSVNSAAARLQSSGVMVAVAAGNNN 163 Query: 328 SDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGY 387 +D+ + PA P V V A D Y R + FS+ + + PG +ILST Sbjct: 164 ADARNYSPASEPSVCTVGASDRYD---RRSSFSNYGSVLDIFGPGTSILSTWI------- 213 Query: 388 EGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLL 423 GG+ GTSMA PHV G+ A L+ Sbjct: 214 -----------GGSTRSISGTSMATPHVAGLAAYLM 238 >4LVN-A nrPDB Length = 344 Score = 89.4 bits (220), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 84/331 (25%), Positives = 139/331 (41%), Gaps = 71/331 (21%) Query: 155 YGEELSNELWGLE--AIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY---- 208 + +E N WGL+ + TQ+L E + + V+D+G+D HPDL+ + Sbjct: 8 FNDEFRNLQWGLDLSRLDETQELINEHQVMSTRICVIDSGIDYNHPDLKDNIELNLKELH 67 Query: 209 -RPAFDEELPAGTDSSYGGS-------------HGTHVAGTIAA-KKDGKGIVGVAPGAK 253 R FD++ D YG + HGTHV+G I+A + G+VGV +K Sbjct: 68 GRKGFDDDNNGIVDDIYGANFVNNSGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVNSK 127 Query: 254 IMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAM 313 ++ D+ L G +GD + + + A ++N S+ YS + +Y Sbjct: 128 LIICKALDEHKL----GRLGDMFKC--LDYCISRNAHMINGSFSFDEYSGIFNSSVEYLQ 181 Query: 314 EHGVVMVVSAGNNTSDS-------------HHQYP----AGYPGVIQVAAL------DYY 350 G++ VSA N + + +YP Y VI VA L ++Y Sbjct: 182 RKGILFFVSASNCSHPKSSTPDIRKCDLSINAKYPPILSTVYDNVISVANLKKNDNNNHY 241 Query: 351 GGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSM 410 + + F S + APG I ST P HN +Y GTSM Sbjct: 242 --SLSINSFYSNK-YCQLAAPGTNIYSTAP---------HN---------SYRKLNGTSM 280 Query: 411 AAPHVTGVVAVLLQKFPNAKPWQIRKLLENT 441 AAPHV + +++ P+ ++ ++L+++ Sbjct: 281 AAPHVAAIASLIFSINPDLSYKKVIQILKDS 311 >3ZXX-A nrPDB Length = 307 Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 81/277 (29%), Positives = 122/277 (44%), Gaps = 52/277 (18%) Query: 183 NIIVAVVDTGVDGTHPDLEG---QVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK 239 NI VA++D VD HP +G V+ P A + +HGTHVA I + Sbjct: 28 NIRVAILDGPVDIAHPCFQGADLTVLPTLAPT------AARSDGFMSAHGTHVASIIFGQ 81 Query: 240 KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWG-- 297 + + G+AP + + + IF D + +A GI A + GA ++N S G Sbjct: 82 PE-TSVPGIAPQCRGLIVPIFSD-----DRRRITQLDLARGIERAVNAGAHIINISGGEL 135 Query: 298 -------GWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYY 350 GW ++ A ++ V++V +AGNN D H PA P V+ V A+D + Sbjct: 136 TDFGEADGW-----LENAVSLCRQNNVLLVAAAGNNGCDCLH-VPAALPAVLAVGAMDDH 189 Query: 351 GGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSM 410 G + + S + + APG IL PG GGT + GTS Sbjct: 190 GHPLDFSNWGSTYEQQGILAPGEDILGAKPG-----------------GGT-ERLSGTSF 231 Query: 411 AAPHVTGVVAVLL----QKFPNAKPWQIRKLLENTAF 443 A P V+GV A+LL ++ P ++R+LL +A Sbjct: 232 ATPIVSGVAALLLSEQVRRGETPDPQKVRQLLLQSAL 268 >3VV3-A nrPDB Length = 334 Score = 86.7 bits (213), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 90/314 (28%), Positives = 137/314 (43%), Gaps = 80/314 (25%) Query: 161 NELWGLEAIGVT----------QQLWEEASGT-NIIVAVVDTGVDGTHPDLEGQV----- 204 ++LWGL G T + W ++G+ +++V V+DTGVD +HPDL Sbjct: 10 DDLWGLNNEGQTGGTADADIDAPEAWSISTGSRDVVVGVIDTGVDYSHPDLAANAWVNSG 69 Query: 205 -IAGYRPAFDEELPAGTDSSYG-------------GSHGTHVAGTIAAKKDGKGIVGVAP 250 IAG D + D +G HGTHV+GTI G + Sbjct: 70 EIAG--DGIDNDGNGYIDDVHGINAITDVGDPMDDEGHGTHVSGTI----------GASG 117 Query: 251 GAKIMPIVIFDDPALVGGNGYVGDDY-VAAGIIWATDH---------GAKVMNHSWGGWG 300 + + + D ++VG D +G I D+ +V+N+SWGG G Sbjct: 118 NNGVGVVGVNHDVSIVGCKFLAADGTGSTSGAIKCIDYMVGLKNAGVNLRVLNNSWGGGG 177 Query: 301 YSYTMKEAFDYAMEHGVVMVVSAGNNT--SDSHHQYPAGYPG--VIQVAALDYYGG--TF 354 +S + +A + + ++ V +AGN+ +D + YP+ Y V+ +A+ D +F Sbjct: 178 FSQALADAITASEQADILFVAAAGNDAVDNDQNPHYPSNYENDNVLSIASTDSRDNMSSF 237 Query: 355 RVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPH 414 G +S V +GAPG ILSTVPG +Y Y GTSMA PH Sbjct: 238 SQWGLTS----VDMGAPGSGILSTVPGN------------------SYATYSGTSMATPH 275 Query: 415 VTGVVAVLLQKFPN 428 V G A++L P+ Sbjct: 276 VAGAAALVLSVNPD 289 >2GKO-A nrPDB Length = 309 Score = 86.7 bits (213), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 100/329 (30%), Positives = 140/329 (42%), Gaps = 59/329 (17%) Query: 164 WGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSS 223 WG++AI L + G I +AV+DTGV+ HPDL V + + Sbjct: 8 WGIKAIYNNSNLTSTSGGAGINIAVLDTGVNTNHPDLSNNVEQCKDFTVGTNFTDNSCTD 67 Query: 224 YGGSHGTHVAGT-IAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGII 282 G HGTHVAG+ +A G G+ GVAP A + + D G+GY D +A I Sbjct: 68 RQG-HGTHVAGSALANGGTGSGVYGVAPEADLWAYKVLGDD----GSGYADD--IAEAIR 120 Query: 283 WATDHGAK-----VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAG 337 A D V+N S G G S + A DYA + GV+++ +AGN+ G Sbjct: 121 HAGDQATALNTKVVINMSLGSSGESSLITNAVDYAYDKGVLIIAAAGNS---GPKPGSIG 177 Query: 338 YPGVIQVAALDY------YGGTFRVAGFSSRSD------------GVSVGAPGVTILSTV 379 YPG + A GT+RVA FSSR V + APG + ST Sbjct: 178 YPGALVNAVAVAALENTIQNGTYRVADFSSRGHKRTAGDYVIQKGDVEISAPGAAVYSTW 237 Query: 380 PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLE 439 ++ G Y GTSMA+PH G+ A + + P A +R L+ Sbjct: 238 -------FD-----------GGYATISGTSMASPHAAGLAAKIWAQSPAASNVDVRGELQ 279 Query: 440 NTAF-------DFNGNGWDHDTGYGLVKL 461 A + G+G D +G+G K+ Sbjct: 280 TRASVNDILSGNSAGSGDDIASGFGFAKV 308 >3F7M-A nrPDB Length = 279 Score = 85.9 bits (211), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 86/268 (32%), Positives = 114/268 (42%), Gaps = 45/268 (16%) Query: 164 WGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQV--IAGYRPAFDEEL 216 WGL I G T ++ ++G V V+DTGV+ THPD EG+ I Y + Sbjct: 9 WGLTRISHRARGSTAYAYDTSAGAGACVYVIDTGVEDTHPDFEGRAKQIKSYASTARD-- 66 Query: 217 PAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVG-GNGYVGDD 275 G HGTH AGTI +K GVA I + + DD N G D Sbjct: 67 --------GHGHGTHCAGTIGSK-----TWGVAKKVSIFGVKVLDDSGSGSLSNIIAGMD 113 Query: 276 YVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYP 335 +VA+ V + S GG GYS + +A GV + V+AGN+ D+ + P Sbjct: 114 FVASDRQSRNCPRRTVASMSLGG-GYSAALNQAAARLQSSGVFVAVAAGNDNRDAANTSP 172 Query: 336 AGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVP 395 A P V V A D R + FS+ V + APG +I ST Sbjct: 173 ASEPTVCTVGATD--SNDVR-STFSNYGRVVDIFAPGTSITSTWI--------------- 214 Query: 396 ATNGGTYDYYQGTSMAAPHVTGVVAVLL 423 GG + GTSMA PH+ G+ A L Sbjct: 215 ---GGRTNTISGTSMATPHIAGLAAYLF 239 >4TR2-A nrPDB Length = 663 Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 86/327 (26%), Positives = 128/327 (39%), Gaps = 66/327 (20%) Query: 155 YGEELSNELWGLE--AIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY---- 208 + +E N WGL+ + TQ L + + V+D+G+D HPDL + Sbjct: 295 FNDEYRNLQWGLDLARLDETQDLINANRVSVTKICVIDSGIDYNHPDLRNNIDVNVKELH 354 Query: 209 -RPAFDEELPAGTDSSYGGS-------------HGTHVAGTIAAK-KDGKGIVGVAPGAK 253 R D++ D YG + HGTHV+G I+A +G GIVGV +K Sbjct: 355 GRKGVDDDSNGVVDDVYGANFVNNSGDPMDDNYHGTHVSGIISAVGNNGIGIVGVDGHSK 414 Query: 254 IMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAM 313 ++ D L G +GD + I + A ++N S+ YS + ++ Sbjct: 415 LVICKALDQHKL----GRLGDMFKC--IDYCISRQAHMINGSFSFDEYSNIFNASVEHLR 468 Query: 314 EHGVVMVVSAGNNTSDS-------------HHQYP----AGYPGVIQVAALDY---YGGT 353 G++ VSA N D +H+YP + VI VA L + Sbjct: 469 SLGILFFVSASNCAHDKLSKPDIAKCDLAVNHRYPPILSKTHNNVIAVANLKRDLDESYS 528 Query: 354 FRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAP 413 V F S + APG I ST P Y GTSMA+P Sbjct: 529 LSVNSFYSNI-YCQLAAPGTNIYSTTPM------------------NNYRKLNGTSMASP 569 Query: 414 HVTGVVAVLLQKFPNAKPWQIRKLLEN 440 HV + +++ PN QI ++L N Sbjct: 570 HVAAIASIVRSINPNLTYLQIVEILRN 596 >1SH7-A nrPDB Length = 284 Score = 85.1 bits (209), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 85/290 (29%), Positives = 126/290 (43%), Gaps = 45/290 (15%) Query: 160 SNELWGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDE 214 SN +WGL+ I + + G + V+DTGV+ H + G+ ++GY ++ Sbjct: 2 SNAIWGLDRIDQRNLPLDRNYNANFDGFGVTAYVIDTGVNNNHEEFGGRSVSGYDFVDND 61 Query: 215 ELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD 274 DSS HGTHVAGTI + GVA I+ + + G+G Sbjct: 62 -----ADSSDCNGHGTHVAGTIGGSQ-----YGVAKNVNIVGVRVLS----CSGSGTTSG 107 Query: 275 DYVAAGIIWATDH--GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH 332 V +G+ W + G V N S GG G S + A A++ GV +++AGN+ +D+ + Sbjct: 108 --VISGVDWVAQNASGPSVANMSLGG-GQSTALDSAVQGAIQSGVSFMLAAGNSNADACN 164 Query: 333 QYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNE 392 PA P + V + + + S D + APG I S Y+G Sbjct: 165 TSPARVPSGVTVGSTTSSDSRSSFSNWGSCVD---LFAPGSQIKSAW-------YDGG-- 212 Query: 393 NVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTA 442 Y GTSMA PHV GV A+ LQ+ P Q+ LL + A Sbjct: 213 ---------YKTISGTSMATPHVAGVAALYLQENNGLTPLQLTGLLNSRA 253 >2B6N-A nrPDB Length = 278 Score = 82.8 bits (203), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 89/286 (31%), Positives = 132/286 (46%), Gaps = 43/286 (15%) Query: 164 WGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WG++ I + + G+ + V+DTGV TH + G+ +GY D + A Sbjct: 8 WGIDRIDQRNLPLDNNYHTDYDGSGVTAFVIDTGVLNTHNEFGGRASSGYD-FIDNDYDA 66 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 TD + HGTHVAGTI G GVA ++ + + + G+G + V Sbjct: 67 -TDCN---GHGTHVAGTI-----GGSTYGVAKNVNVVGVRVLN----CSGSG--SNSGVI 111 Query: 279 AGIIWATDH--GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPA 336 AGI W ++ G V N S GG G S +A + A+ G+ VV+AGN+ S++ + PA Sbjct: 112 AGINWVKNNASGPAVANMSLGG-GASQATDDAVNAAVAAGITFVVAAGNDNSNACNYSPA 170 Query: 337 GYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPA 396 I V + + FS+ + + APG +I S+ +S A Sbjct: 171 RAADAITVGSTT---SNDSRSSFSNYGTCLDIYAPGSSITSSWYTSNS-----------A 216 Query: 397 TNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTA 442 TN GTSMA+PHV GV A+ L + PN P Q+ LL+ A Sbjct: 217 TN-----TISGTSMASPHVAGVAALYLDENPNLSPAQVTNLLKTRA 257 >5Z6O-A nrPDB Length = 282 Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 102/230 (44%), Gaps = 34/230 (14%) Query: 164 WGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WGL I G T +++ +G I++ VDTG+D H D G+ G A +++ Sbjct: 11 WGLSRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADNDD--- 67 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 TD G HGTH A T A K GVA A ++ + + G +G + V Sbjct: 68 -TD---GNGHGTHTASTAAGSK-----FGVAKKASVVAVKVL------GADGSGTNSQVI 112 Query: 279 AGIIWATDH-------GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSH 331 AG+ WA G VMN S GG YS M +A + GV + V+AGN D+ Sbjct: 113 AGMDWAVKDSKSRGATGKSVMNMSLGG-AYSRAMNDAAANVVRSGVFLSVAAGNEAQDAS 171 Query: 332 HQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPG 381 + PA P V +AA G+ F S D + APG I + PG Sbjct: 172 NSSPASAPNVCTIAASTNSDGSASFTNFGSVVD---LYAPGKDITAAYPG 218 >4H6W-A nrPDB Length = 306 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 82/299 (27%), Positives = 129/299 (43%), Gaps = 37/299 (12%) Query: 173 QQLWEEASGT-NIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTH 231 ++LW E G I VAV+D VD HP G + E A S +HGTH Sbjct: 11 KKLWSETRGDPKICVAVLDGIVDQNHPCFIGADLTRLPSLVSGEANANGSMS---THGTH 67 Query: 232 VAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKV 291 VA I + D + G+AP + + + +F D +L + ++ I A ++GA + Sbjct: 68 VASIIFGQHDSP-VTGIAPQCRGLIVPVFADESL-----KLSQLDLSRAIEQAVNNGANI 121 Query: 292 MNHSWGGW---GYSYT-MKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAAL 347 +N S G G + T +++A E+ V+++ + GN+ + H PA P V+ V A+ Sbjct: 122 INVSAGQLTDAGEADTWLEKAIQLCQENNVLLIAATGNDGCECLH-VPASLPTVLAVGAM 180 Query: 348 DYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQG 407 D G + + + APG IL P NGGT G Sbjct: 181 DDQGKPVDFSNWGDAYQKQGILAPGKDILGAKP-----------------NGGTI-RLSG 222 Query: 408 TSMAAPHVTGVVAVLL----QKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLD 462 TS A P V+GV A+LL ++ P +++ L +A N D + + KL+ Sbjct: 223 TSFATPIVSGVAALLLSLQIKRGEKPDPQKVKNALLASATPCNPKDTDDQSRCLMGKLN 281 >5WSL-A nrPDB Length = 299 Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 77/282 (27%), Positives = 124/282 (43%), Gaps = 43/282 (15%) Query: 164 WGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WGL+ I ++ +G+ + ++DTG+ +H + G+ A FD + Sbjct: 8 WGLDRIDQRTLPLSGTFTYSNTGSGVNAYIIDTGIRVSHSEFGGRATA----VFDA-IGD 62 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 G + + HGTHVAGT+ G + GVA ++ + + + G+G + V Sbjct: 63 GQNGNDCNGHGTHVAGTV-----GGTVYGVAKSVRLYAVRVLN----CSGSG--SNSGVI 111 Query: 279 AGIIWATDHGAK--VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPA 336 AG+ W + + V N S GG G S + A + A+ G+ ++AGN+ D+ PA Sbjct: 112 AGVDWVRQNARRPAVANMSLGG-GASSALDTAVNNAINAGITFALAAGNSNRDACQFSPA 170 Query: 337 GYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPA 396 I V A T A +S+ + + APG +I S D+ Sbjct: 171 RVTAGITVGATT---STDARASYSNYGSCLDLFAPGSSITSAWISSDT------------ 215 Query: 397 TNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLL 438 + + GTSMA PHV GV A+ LQ P+A P +R + Sbjct: 216 ----STNTISGTSMATPHVAGVAALYLQSNPSASPATVRNAI 253 >3AFG-A nrPDB Length = 539 Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 86/267 (32%), Positives = 127/267 (47%), Gaps = 47/267 (17%) Query: 196 THPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIA---AKKDGKGIVGVAPGA 252 +HPDL+G+VI + P + HGTHVA A A +GK G+APGA Sbjct: 153 SHPDLQGKVIGWVDFVNGKTTPYDDN-----GHGTHVASIAAGTGAASNGK-YKGMAPGA 206 Query: 253 KIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATD----HGAKVMNHSWGGWGYS---YTM 305 K++ I + + G+G + D + G+ WA +G KV+N S G S ++ Sbjct: 207 KLVGIKVLNGQ----GSGSISD--IINGVDWAVQNKDKYGIKVINLSLGSSQSSDGTDSL 260 Query: 306 KEAFDYAMEHGVVMVVSAGNNTSDSHH-QYPAGYPGVIQVAALDYYGGTFRVAGFSSRSD 364 +A + A + G+V+VV+AGN+ + + PA VI V A+D Y + FSSR Sbjct: 261 SQAVNNAWDAGLVVVVAAGNSGPNKYTVGSPAAASKVITVGAVDKYD---VITDFSSRGP 317 Query: 365 GV------SVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQ---GTSMAAPHV 415 V APG I++ S+G + DYY GT+MA PHV Sbjct: 318 TADNRLKPEVVAPGNWIIAARASGTSMGQPIN------------DYYTAAPGTAMATPHV 365 Query: 416 TGVVAVLLQKFPNAKPWQIRKLLENTA 442 G+ A+LLQ P+ P +++ L TA Sbjct: 366 AGIAALLLQAHPSWTPDKVKTALIETA 392 >4MZD-A nrPDB Length = 488 Score = 77.0 bits (188), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 90/312 (28%), Positives = 126/312 (40%), Gaps = 60/312 (19%) Query: 184 IIVAVVDTGVDGTHPDLE---GQVIAGYRPA--FDEELPAGT----DSSYGGSHGTHVAG 234 I V ++D+G+ HPDL G P FD E P T D HGT VAG Sbjct: 94 ISVGIIDSGIMEEHPDLSNSLGNYFKNLVPKGGFDNEEPDETGNPSDIVDKMGHGTEVAG 153 Query: 235 TIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNH 294 I A + I+GVAPG + +F G ++VA I A D G KV+N Sbjct: 154 QITANGN---ILGVAPGITVNIYRVF-------GENLSKSEWVARAIRRAADDGNKVINI 203 Query: 295 SWGGW---GYSY-----------TMKEAFDYAMEHGVVMVVSAGN---NTSDSHHQY--- 334 S G + SY K A +YA G ++V + GN N D+ Sbjct: 204 SAGQYLMISGSYDDGTNDYQEYLNYKSAINYATAKGSIVVAALGNDSLNIQDNQTMINFL 263 Query: 335 ---------------PAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTV 379 P+ + VI V +D YG ++ FS+ G T Sbjct: 264 KRFRSIKVPGKVVDAPSVFEDVIAVGGIDGYGN---ISDFSNIGADAIYAPAGTTANFKK 320 Query: 380 PGED---SIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRK 436 G+D S GY + TN G Y Y G S A P V+G +A+++ K+ P Q+++ Sbjct: 321 YGQDKFVSQGYYLKDWLFTTTNTGWYQYVYGNSFATPKVSGALALVVDKYGIKNPNQLKR 380 Query: 437 LLENTAFDFNGN 448 L + + NGN Sbjct: 381 FLLMNSPEVNGN 392 >3QFH-A nrPDB Length = 447 Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 98/412 (23%), Positives = 163/412 (39%), Gaps = 85/412 (20%) Query: 64 VGYNDRSEVDKIVKAVNGKVVLELPQIKVVSIKLNGMTVKQAYDKIKALA--LKGIRYVE 121 V Y + + +K+VK + VV +P++ V IK+ M ALA I+Y+ Sbjct: 25 VEYKNTATFNKLVKKKSLNVVYNIPELHVAQIKMTKMHAN-------ALANYKNDIKYIN 77 Query: 122 PSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEA-S 180 + + + R E L + W + I +++ Sbjct: 78 ATCSTCITSEKTID-----------------RTSNESLFSRQWDMNKITNNGASYDDLPK 120 Query: 181 GTNIIVAVVDTGVDGTHPDLEGQV---------IAGYRPAFDEELPAGTDSSYGGSHGTH 231 N +A++DTGV H DL+ + G+R EE D + HGT Sbjct: 121 HANTKIAIIDTGVMKNHDDLKNNFSTDSKNLVPLNGFRGTEPEETGDVHDVNDRKGHGTM 180 Query: 232 VAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKV 291 V+G +A +GK ++GVAP K +F G+ +V+ I+ A + G +V Sbjct: 181 VSGQTSA--NGK-LIGVAPNNKFTMYRVF-------GSKKTELLWVSKAIVQAANDGNQV 230 Query: 292 MNHSWGGW---------------GYSY-TMKEAFDYAMEHGVVMVVSAGNNTSDSHHQY- 334 +N S G + Y +++A +YA + ++V +AGN+ D + + Sbjct: 231 INISVGSYIILDKNDHQTFRKDEKVEYDALQKAINYAKKKKSIVVAAAGNDGIDVNDKQK 290 Query: 335 ----------------PAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILST 378 PA V+ V + D + F + + APG + Sbjct: 291 LKLQREYQGNGEVKDVPASMDNVVTVGSTDQKSNLSEFSNFGM--NYTDIAAPGGSFAYL 348 Query: 379 VP-GEDSIGYEG--HNENVPAT-NGGTYDYYQGTSMAAPHVTGVVAVLLQKF 426 G D EG H EN+ T N G Y Y GTS+A P V+G +A+++ K+ Sbjct: 349 NQFGVDKWMNEGYMHKENILTTANNGRYIYQAGTSLATPKVSGALALIIDKY 400 >3F7O-A nrPDB Length = 284 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 42/280 (15%) Query: 164 WGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WGL I G T ++ + G+ V+DTGV+ +HP+ EG R + + + Sbjct: 10 WGLGRISHRSKGSTTYEYDTSGGSGTCAYVIDTGVEASHPEFEG------RASQIKSFIS 63 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYV-GDDYV 277 G ++ G HGTH AGTI +K GVA KI + + D+ +G + G D+ Sbjct: 64 GQNTD-GNGHGTHCAGTIGSK-----TYGVAKKTKIYGVKVLDNSGSGSYSGIISGMDFA 117 Query: 278 AAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAG 337 + V N S GG G + ++ + + GV + V+AGN+ +++ + PA Sbjct: 118 VQDSKSRSCPKGVVANMSLGG-GKAQSVNDGAAAMIRAGVFLAVAAGNDNANAANYSPAS 176 Query: 338 YPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPAT 397 P V V A + + FS+ + V + APG ILST Sbjct: 177 EPTVCTVGATT---SSDARSSFSNYGNLVDIFAPGSNILSTWI----------------- 216 Query: 398 NGGTYDYYQGTSMAAPHVTGVVAVL--LQKFPNAKPWQIR 435 GGT + GTSMA PH+ G+ A L L+ FP A+ R Sbjct: 217 -GGTTNTISGTSMATPHIVGLGAYLAGLEGFPGAQALCKR 255 >4KB5-A nrPDB Length = 408 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 103/404 (25%), Positives = 164/404 (40%), Gaps = 86/404 (21%) Query: 121 EPSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEAS 180 +P+ +R++ V PN ++ W + + + Q+ + A+ Sbjct: 21 QPTEQRKICATPTVMPN-------------------SNFADRPWANDYLRI-QEAQKFAT 60 Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK 240 G + VAV+DTGV+G+ P + + P D AG S +HGT A I + Sbjct: 61 GAGVTVAVIDTGVNGS-PRVPAE------PGGDFVDAAGNGMSDCDAHGTMTAAIIGGRP 113 Query: 241 D-GKGIVGVAPGAKIMPI----VIF---------DDPALVGGNGYVGDDYVAAGIIWATD 286 G VG+AP +++ + V F +DP G + +A ++ A + Sbjct: 114 SPTDGFVGMAPDVRLLSLRQTSVAFQPKGARQDPNDPNTTQTAGSI--RSLARSVVHAAN 171 Query: 287 HGAKVMNHSWGGWGYSYTMK-------EAFDYAME-HGVVMVVSAGNNTSDSHHQY---- 334 GA+V+N S Y T + A +YA+ G V+VV+AGN D Sbjct: 172 LGAQVINISEAAC-YKVTRRIDETSLGAAINYAVNVKGAVIVVAAGNTGQDCSQNPPPDP 230 Query: 335 -----------------PAGY-PGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTIL 376 PA Y P V+ V ++ G + + FS V APG + Sbjct: 231 SVPSDPRGWREVQTIVSPAWYDPLVLTVGSIGQNG---QPSNFSMSGPWVGAAAPGENLT 287 Query: 377 STVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRK 436 S +GY+G N G GTS +A +V+G+ A++ Q+FP+ P QI Sbjct: 288 S-------LGYDGQPVNATPGEDGPVPL-NGTSFSAAYVSGLAALVKQRFPDLTPAQIIN 339 Query: 437 LLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLPTQGGVEEFQV 480 + TA G G D+ G G++ AAL +P F+V Sbjct: 340 RITATAR-HPGGGVDNYVGAGVIDPVAALTWEIPDGPEKAPFRV 382 >4DZT-A nrPDB Length = 276 Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 86/286 (30%), Positives = 123/286 (43%), Gaps = 45/286 (15%) Query: 164 WGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WGL+ I ++ A+G + V V+DTG+ TH + G+ GY D Sbjct: 8 WGLDRIDQRDLPLSNSYTYTATGRGVNVYVIDTGIRTTHREFGGRARVGY----DALGGN 63 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 G D + HGTHVAGTI G GVA + + + D NG V Sbjct: 64 GQDCN---GHGTHVAGTI-----GGVTYGVAKAVNLYAVRVLD------CNGSGSTSGVI 109 Query: 279 AGIIWATDHGAK--VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPA 336 AG+ W T + + V N S GG G S + A ++ GVV V+AGN+ +++ + PA Sbjct: 110 AGVDWVTRNHRRPAVANMSLGG-GVSTALDNAVKNSIAAGVVYAVAAGNDNANACNYSPA 168 Query: 337 GYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPA 396 + V A + A FS+ V + APG +I S D+ Sbjct: 169 RVAEALTVGATT---SSDARASFSNYGSCVDLFAPGASIPSAWYTSDT------------ 213 Query: 397 TNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTA 442 GTSMA PHV GV A+ L++ P+A P + + N A Sbjct: 214 ----ATQTLNGTSMATPHVAGVAALYLEQNPSATPASVASAILNGA 255 >4ZOQ-I nrPDB Length = 343 Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 93/361 (25%), Positives = 152/361 (42%), Gaps = 91/361 (25%) Query: 164 WGLEAI-GVTQQLWEEASGTN-------------IIVAVVDTGVDGTHPDLEGQVIAGYR 209 WGL+ I + + LW A T+ + VA++D+G+D HPDL+ V Sbjct: 11 WGLDGILELKEYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPDLKASVNTNGG 70 Query: 210 PAFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGN 269 + + P D + HGT AG I +AP I P + D+ GG+ Sbjct: 71 WNYIDGKPVSGDPT---GHGTQTAGMINI---------IAPDVTITPYQVLDEK---GGD 115 Query: 270 GYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYT------------MKEAFDYAMEHGV 317 Y + ++ A + G +V+N S G SYT + A +YA +H V Sbjct: 116 SY----NIMKAMVDAVNDGHEVINISTG----SYTSLDREGKVLMKAYQRAANYAAKHQV 167 Query: 318 VMVVSAGNN--------TSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVG 369 ++ SAGN +++ P+ V+ V + + ++ +S++ + Sbjct: 168 LVFSSAGNKGVNLDEMRKTENKVHLPSALKHVVSVGS---NMKSNNISPYSNQGREIEFT 224 Query: 370 APG--------------VT--ILSTVP-GEDSIGYEGHNENVPATNGGTYDYYQGTSMAA 412 APG VT +L+T P G+D+ + N+P Y GTS+AA Sbjct: 225 APGGYLGETYDQDGMVRVTDLVLTTYPKGKDNTALD-QMLNIPK----GYSLSYGTSLAA 279 Query: 413 PHVTGVVAVLLQKF-------PNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAAL 465 P V G A+++ ++ P+AK Q+ +L +A D G D GYG V+ AL Sbjct: 280 PQVAGTAALVISEYRERHHRKPSAK--QVHHILRKSALDLGKPGKDVIYGYGEVRAYQAL 337 Query: 466 Q 466 + Sbjct: 338 K 338 >4HVL-A nrPDB Length = 377 Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 100/375 (26%), Positives = 154/375 (41%), Gaps = 50/375 (13%) Query: 128 LIKPTVVKPN---PD--MYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEASGT 182 +I P V P+ PD M + R + D ++ W + + +T+ + A+G Sbjct: 6 VIDPAAVPPDETGPDNPMEQRRVCAAPTVYPD--SNFADRPWASDYLRLTEA-HKFATGA 62 Query: 183 NIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK-KD 241 I VAV+DTGV+G+ P + + P D AG S +HGT A IA + Sbjct: 63 GITVAVIDTGVNGS-PRVPAE------PGGDFVDAAGNGMSDCDAHGTLTASVIAGRGAP 115 Query: 242 GKGIVGVAPGAKIM----------PIVIFDDPALVGGNGYVGD-DYVAAGIIWATDHGAK 290 G +GVAP A+I+ P+ DP G +A I+ A + GA+ Sbjct: 116 TDGFIGVAPDARILSLRHTSAAFQPVGARTDPNNPNTTQTAGSLRSLARAIVHAANLGAQ 175 Query: 291 VMNHSWGGWGYSYT-------MKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQ 343 V+N S Y T + A +YA+ +V++A NT Q P P V Sbjct: 176 VINISEAAC-YKVTRPIDETGVGAAVNYAVHVKNAVVIAAAGNTGQDCTQNPPPDPAVPS 234 Query: 344 -----------VAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGED--SIGYEGH 390 V+ Y V G + G + + P E+ ++GY G Sbjct: 235 DPRGWQQVQTIVSPAWYSPLVLTVGGIGPTGQPSNFSMSGPWVGAAAPAENITALGYGGE 294 Query: 391 NENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGW 450 N G GTS AA +V+G+ A++ Q++P+ P Q+ + TA G G Sbjct: 295 PVNALQGQDGLVPV-AGTSFAAAYVSGLAALIRQRYPDLTPAQVINRITATA-RHPGGGV 352 Query: 451 DHDTGYGLVKLDAAL 465 D+ G G++ AAL Sbjct: 353 DNYVGAGVIDPVAAL 367 >5FAX-A nrPDB Length = 433 Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 91/317 (28%), Positives = 127/317 (40%), Gaps = 60/317 (18%) Query: 185 IVAVVDTGVD------GTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAA 238 IVAV DTG+D H G++ A Y L +++ HGTHVAG++ Sbjct: 25 IVAVADTGLDTGRNDSSMHEAFRGKITALY------ALGRTNNANDPNGHGTHVAGSVLG 78 Query: 239 KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI----IWATDHGAKVMNH 294 KG+ AP A ++ I D +GG + A + A GA++ + Sbjct: 79 NATNKGM---APQANLVFQSIMDSGGGLGG--------LPANLQTLFSQAYSAGARIHTN 127 Query: 295 SWGG---WGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH-QYPAGYPGVIQVAALDYY 350 SWG Y+ + DY ++ + ++ +AGN S P I V A + Sbjct: 128 SWGAPVNGAYTTDSRNVDDYVRKNDMTILFAAGNEGPGSGTISAPGTAKNAITVGATENL 187 Query: 351 GGTF--------RVAGFSSR---SDGV---SVGAPGVTILSTVP--GEDSIGYEGHNENV 394 +F VA FSSR DG V APG ILS DS + H+ Sbjct: 188 RPSFGSYADNINHVAQFSSRGPTRDGRIKPDVMAPGTYILSARSSLAPDSSFWANHDSK- 246 Query: 395 PATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPN-----AKPWQIRKLLENTAFDFNGNG 449 Y Y GTSMA P V G VA L + F KP ++ L A D Sbjct: 247 -------YAYMGGTSMATPIVAGNVAQLREHFVKNRGVTPKPSLLKAALIAGAADVGLGF 299 Query: 450 WDHDTGYGLVKLDAALQ 466 + + G+G V LD +L Sbjct: 300 PNGNQGWGRVTLDKSLN 316 >4KG7-A nrPDB Length = 381 Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 86/309 (27%), Positives = 124/309 (40%), Gaps = 57/309 (18%) Query: 176 WEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGT 235 W+ + G VAV+DTGV P L G + E TD HGT VAG Sbjct: 59 WQHSRGAGQTVAVIDTGVQ-PGPRLPNVEAGGD---YIESTDGLTDCD---GHGTSVAGL 111 Query: 236 IAAKKDGKGIVGVAPGAKIMPIVIFDD---PALVGGNGYVGD-----DYVAAGIIWATDH 287 IA + G GVAP A+++ I P G + + +A ++ A D Sbjct: 112 IAGQPGPDGFSGVAPEARLISIRQNSPRFAPRTPGADSEATRAASDAETLARAVVRAADM 171 Query: 288 GAKVMNHSW-GGWGYSYTMKE-----AFDY-AMEHGVVMVVSAGNN-------TSDSHHQ 333 GA+V+N S T+ + A Y A+E V+V +AGNN + + Sbjct: 172 GARVINISLVTCLPADRTIDQSVLGAALRYAALEKDAVIVAAAGNNRGGVSTGAACESNP 231 Query: 334 YPAGYPG--------------------VIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGV 373 P+G PG V+ V A+D G + + F+ V + APG Sbjct: 232 LPSGTPGDPRNWNGVTSVSIPSWWQPYVLSVGAVDSTG---QPSSFTMAGPWVGIAAPGE 288 Query: 374 TILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQ 433 I+S S +G N + GTS AA +V+GV A++ KFP+ Q Sbjct: 289 NIVSV-----SNAPDGGLSNALPSERDRLVPLTGTSYAAAYVSGVAALVRSKFPDLTARQ 343 Query: 434 IRKLLENTA 442 + L TA Sbjct: 344 VVHRLTTTA 352 >1WMD-A nrPDB Length = 434 Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 87/313 (27%), Positives = 124/313 (39%), Gaps = 51/313 (16%) Query: 185 IVAVVDTGVD------GTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAA 238 IVAV DTG+D H G++ A Y L +++ HGTHVAG++ Sbjct: 25 IVAVADTGLDTGRNDSSMHEAFRGKITALY------ALGRTNNANDTNGHGTHVAGSVLG 78 Query: 239 KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGG 298 +G G+AP A ++ I D + + A GA++ +SWG Sbjct: 79 --NGSTNKGMAPQANLVFQSIMDSGGGL----GGLPSNLQTLFSQAYSAGARIHTNSWGA 132 Query: 299 W---GYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH-QYPAGYPGVIQVAALDYYGGTF 354 Y+ + DY ++ + ++ +AGN + P I V A + +F Sbjct: 133 AVNGAYTTDSRNVDDYVRKNDMTILFAAGNEGPNGGTISAPGTAKNAITVGATENLRPSF 192 Query: 355 --------RVAGFSSR---SDGV---SVGAPGVTILSTVP--GEDSIGYEGHNENVPATN 398 VA FSSR DG V APG ILS DS + H+ Sbjct: 193 GSYADNINHVAQFSSRGPTKDGRIKPDVMAPGTFILSARSSLAPDSSFWANHDSK----- 247 Query: 399 GGTYDYYQGTSMAAPHVTGVVAVLLQKFPN-----AKPWQIRKLLENTAFDFNGNGWDHD 453 Y Y GTSMA P V G VA L + F KP ++ L A D + + Sbjct: 248 ---YAYMGGTSMATPIVAGNVAQLREHFVKNRGITPKPSLLKAALIAGAADIGLGYPNGN 304 Query: 454 TGYGLVKLDAALQ 466 G+G V LD +L Sbjct: 305 QGWGRVTLDKSLN 317 >2W2P-A nrPDB Length = 312 Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 82/304 (26%), Positives = 124/304 (40%), Gaps = 48/304 (15%) Query: 164 WGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAG 219 W LE I + +E G+ + V ++DT + H ++EG+V+ EE G Sbjct: 4 WNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEE--DG 61 Query: 220 T----DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDD 275 T +S SHGTH+AG ++ + GVA GA + + + + G G V Sbjct: 62 TRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVLN----CQGKGTVSGT 112 Query: 276 YVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSH 331 + I + G V+ G GYS + A GVV+V +AGN D+ Sbjct: 113 LIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAGVVLVTAAGNFRDDAC 171 Query: 332 HQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTV----PGEDSIGY 387 PA P VI V A + ++ V++G G V PGED IG Sbjct: 172 LYSPASAPEVITVGATN------------AQDQPVTLGTLGTNFGRCVDLFAPGEDIIGA 219 Query: 388 EGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIR-KLLENTAFDFN 446 + + GTS AA HV G+ A++L P ++R +L+ +A D Sbjct: 220 S-------SACSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVI 272 Query: 447 GNGW 450 W Sbjct: 273 NEAW 276 >5VLH-A nrPDB Length = 460 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 87/319 (27%), Positives = 129/319 (40%), Gaps = 53/319 (16%) Query: 154 DYGEELSNEL-----WGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQV 204 DY EE S+ W LE I + +E G+ + V ++DT + H ++EG+V Sbjct: 141 DYIEEDSSVFAQSIPWNLERITPPRYSADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRV 200 Query: 205 IAGYRPAFDEELPAGT----DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIF 260 + EE GT +S SHGTH+AG ++ + GVA GA + + + Sbjct: 201 MVTDFENVPEE--DGTRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVL 253 Query: 261 DDPALVGGNGYVGDDYVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHG 316 + G G V + I + G V+ G GYS + A G Sbjct: 254 N----CQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAG 308 Query: 317 VVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTIL 376 VV+V +AGN D+ PA P VI V A + ++ V++G G Sbjct: 309 VVLVTAAGNFRDDACLYSPASAPEVITVGATN------------AQDQPVTLGTLGTNFG 356 Query: 377 STV----PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPW 432 V PGED IG + GTS AA HV G+ A++L P Sbjct: 357 RCVDLFAPGEDIIGASSDCSTC-------FVSQSGTSQAAAHVAGIAAMMLSAEPELTLA 409 Query: 433 QIR-KLLENTAFDFNGNGW 450 ++R +L+ +A D W Sbjct: 410 ELRQRLIHFSAKDVINEAW 428 >6F5G-A nrPDB Length = 703 Score = 55.5 bits (132), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 87/319 (27%), Positives = 129/319 (40%), Gaps = 53/319 (16%) Query: 154 DYGEELSNEL-----WGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQV 204 DY EE S+ W LE I + +E G+ + V ++DT + H ++EG+V Sbjct: 141 DYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRV 200 Query: 205 IAGYRPAFDEELPAGT----DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIF 260 + EE GT +S SHGTH+AG ++ + GVA GA + + + Sbjct: 201 MVTDFENVPEE--DGTRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVL 253 Query: 261 DDPALVGGNGYVGDDYVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHG 316 + G G V + I + G V+ G GYS + A G Sbjct: 254 N----CQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAG 308 Query: 317 VVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTIL 376 VV+V +AGN D+ PA P VI V A + ++ V++G G Sbjct: 309 VVLVTAAGNFRDDACLYSPASAPEVITVGATN------------AQDQPVTLGTLGTNFG 356 Query: 377 STV----PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPW 432 V PGED IG + GTS AA HV G+ A++L P Sbjct: 357 RCVDLFAPGEDIIGASSDCSTC-------FVSQSGTSQAAAHVAGIAAMMLSAEPELTLA 409 Query: 433 QIR-KLLENTAFDFNGNGW 450 ++R +L+ +A D W Sbjct: 410 ELRQRLIHFSAKDVINEAW 428 >4K8R-B nrPDB Length = 548 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 82/304 (26%), Positives = 123/304 (40%), Gaps = 48/304 (15%) Query: 164 WGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAG 219 W LE I + +E G+ + V ++DT + H ++EG+V+ EE G Sbjct: 4 WNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEE--DG 61 Query: 220 T----DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDD 275 T +S SHGTH+AG ++ + GVA GA + + + + G G V Sbjct: 62 TRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVLN----CQGKGTVSGT 112 Query: 276 YVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSH 331 + I + G V+ G GYS + A GVV+V +AGN D+ Sbjct: 113 LIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAGVVLVTAAGNFRDDAC 171 Query: 332 HQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTV----PGEDSIGY 387 PA P VI V A + ++ V++G G V PGED IG Sbjct: 172 LYSPASAPEVITVGATN------------AQDQPVTLGTLGTNFGRCVDLFAPGEDIIGA 219 Query: 388 EGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIR-KLLENTAFDFN 446 + GTS AA HV G+ A++L P ++R +L+ +A D Sbjct: 220 SSDCSTC-------FVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVI 272 Query: 447 GNGW 450 W Sbjct: 273 NEAW 276 >1XF1-A nrPDB Length = 926 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 57/192 (29%), Positives = 83/192 (43%), Gaps = 41/192 (21%) Query: 173 QQLWEEA-SGTNIIVAVVDTGVDGTHP--DLEGQVIAGYRPAFDEELPAGT--------- 220 + L E+A G +VAV+D G D H L + A Y+ D E Sbjct: 7 KTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWV 66 Query: 221 --------DSSYGG------SHGTHVAGTIAAK-----KDGKGIVGVAPGAKIMPIVIFD 261 D S G HGTHV+G ++ K+ + G P A+++ + + Sbjct: 67 NDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRV-- 124 Query: 262 DPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYT-----MKEAFDYAMEHG 316 +V G +Y A I A + GAKV+N S+G +Y K+AFDYA G Sbjct: 125 --EIVNGLADYARNY-AQAIRDAINLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKG 181 Query: 317 VVMVVSAGNNTS 328 V +V SAGN++S Sbjct: 182 VSIVTSAGNDSS 193 >2ID4-A nrPDB Length = 503 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 77/318 (24%), Positives = 127/318 (39%), Gaps = 45/318 (14%) Query: 169 IGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSH 228 I V + +G ++ A+VD G+D + DL+ A F++ H Sbjct: 41 INVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYH 100 Query: 229 GTHVAGTIAAKKDGKGIVGVAPG--AKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATD 286 GT AG IAAKK G GV G AKI I I +G + + AA +I+ D Sbjct: 101 GTRCAGEIAAKK-GNNFCGVGVGYNAKISGIRIL--------SGDITTEDEAASLIYGLD 151 Query: 287 HGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAA 346 + + SWG ++ D ++ +V V+ G ++ + + + +G G Sbjct: 152 VN-DIYSCSWGPADDGRHLQGPSDL-VKKALVKGVTEGRDSKGAIYVFASGNGGT----- 204 Query: 347 LDYYGGTFRVAGFSSRSDGVSVGA-----------PGVTILSTVPGEDSIGYEGHNENVP 395 G G+++ +++GA G + + V G H+ ++ Sbjct: 205 ---RGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSGEYIHSSDI- 260 Query: 396 ATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNA--KPWQIRKLLENTAFDFNGNGWDHD 453 NG + + GTS AAP GV +LL+ PN + Q +L + N +G D Sbjct: 261 --NGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRD 318 Query: 454 TG--------YGLVKLDA 463 + YG K+DA Sbjct: 319 SAMGKKYSHRYGFGKIDA 336 >4H6X-A nrPDB Length = 357 Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 54/219 (24%), Positives = 92/219 (42%), Gaps = 28/219 (12%) Query: 211 AFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGN- 269 A + +P D H HV TI ++ + G+AP ++ + A++ GN Sbjct: 92 ALEAVIPDTKDRIVLNDHACHVTSTIVGQEHSP-VFGIAPNCRV---INMPQDAVIRGNY 147 Query: 270 -GYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKE----AFDYAMEHGVVMVVSAG 324 + +A I A + GA +++ ++ + +E A ++ V++V G Sbjct: 148 DDVMSPLNLARAIDLALELGANIIHCAFCRPTQTSEGEEILVQAIKKCQDNNVLIVSPTG 207 Query: 325 NNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDS 384 NN+++S PA PG + V A G + + + + APG IL P + Sbjct: 208 NNSNESWC-LPAVLPGTLAVGAAKVDGTPCHFSNWGGNNTKEGILAPGEEILGAQPCTE- 265 Query: 385 IGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLL 423 E V T GTSMAAP +TG+ A+L+ Sbjct: 266 -------EPVRLT---------GTSMAAPVMTGISALLM 288 >3HJR-A nrPDB Length = 600 Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 73/313 (23%), Positives = 121/313 (38%), Gaps = 63/313 (20%) Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK 240 G + VAVVD G+ HPDL V G + T + +HGT V+G IAA Sbjct: 69 GQGVNVAVVDDGLAIAHPDLADNVRPGSKNVVTGSD-DPTPTDPDTAHGTSVSGIIAAVD 127 Query: 241 DGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWG 300 + G G+AP A++ + DD + + D++ A +V N S+G Sbjct: 128 NAIGTKGIAPRAQLQGFNLLDD-----NSQQLQKDWLYALGDSNASRDNRVFNQSYGMSV 182 Query: 301 YSYTMKEAFDYAM-----------EHGVVMVVSAGN------------NTSDSHHQYPAG 337 + D + G + +AGN N + + + P Sbjct: 183 VDPRSANSLDQSQLDRLFEQQTLKAQGAAYIKAAGNGFNKIAAGGYVLNRTGNGPKLPFE 242 Query: 338 YPGV---------IQVAALDYYGGTFRVAGFSSRSDGVSVGAPG--------VTILSTVP 380 + + V+AL+ G + +SS + + A G + + +P Sbjct: 243 NSNLDPSNSNFWNLVVSALNADGVR---SSYSSVGSNIFLSATGGEYGTDTPAMVTTDLP 299 Query: 381 GEDSIGYEGHNENVPATN--------GGTYDY---YQGTSMAAPHVTGVVAVLLQKFPNA 429 G D +GY ++ P+TN + DY GTS A P +G +A+L+ +P+ Sbjct: 300 GCD-MGYNRTDD--PSTNRLHGNSQLDASCDYNGVMNGTSSATPSTSGAMALLMSAYPDL 356 Query: 430 KPWQIRKLLENTA 442 +R LL +A Sbjct: 357 SVRDLRDLLARSA 369 >5MIM-A nrPDB Length = 482 Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 80/329 (24%), Positives = 125/329 (37%), Gaps = 58/329 (17%) Query: 170 GVTQQ------LWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT-- 220 GVTQ+ W + +G I+V+++D G++ HPDL G G +++ P Sbjct: 19 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 78 Query: 221 -DSSYGGSHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 HGT AG +AA +G VGVA A+I + + D G V D A Sbjct: 79 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--------GEVTDAVEA 130 Query: 279 AGIIWATDHGAKVMNHSWGGW-------GYSYTMKEAFDYAMEH-----GVVMVVSAGNN 326 + +H + + SWG G + +EAF + G + V ++GN Sbjct: 131 RSLGLNPNH-IHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 189 Query: 327 TSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIG 386 + GY I ++ V +S ST+ S G Sbjct: 190 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE------------ACSSTLATTYSSG 237 Query: 387 YEGHNENVPAT-NGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTA--F 443 + + V + + GTS +AP G++A+ L+ N ++ L+ T+ Sbjct: 238 NQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPA 297 Query: 444 DFNGNGW---------DHDTGYGLVKLDA 463 N N W H GYGL LDA Sbjct: 298 HLNANDWATNGVGRKVSHSYGYGL--LDA 324 >4I0W-B nrPDB Length = 477 Score = 37.7 bits (86), Expect = 0.016, Method: Compositional matrix adjust. Identities = 43/149 (28%), Positives = 64/149 (42%), Gaps = 39/149 (26%) Query: 335 PAGYPGVIQVAALDYYGGTFRVAGFSSRSDGV---------SVGAPGVTILSTVPGEDSI 385 PA GVI V + ++ ++ FS R GV + APG ILSTV + Sbjct: 337 PATVEGVISVGSYNFLNNN--LSAFSGR--GVVRPEWLIKPDLVAPGENILSTVEEQG-- 390 Query: 386 GYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQ--KFPNAKPW----QIR-KLL 438 +D GTSMAAP V+G+ A+L + N P+ +I+ L+ Sbjct: 391 ----------------FDTKSGTSMAAPQVSGICALLFEWGIIRNNDPFLYGERIKYYLI 434 Query: 439 ENTAFDFNGNGW-DHDTGYGLVKLDAALQ 466 + G + + D GYG V LD ++ Sbjct: 435 KGAKRTIFGEAYPNPDLGYGFVCLDRTME 463 >2ZY2-A nrPDB Length = 544 Score = 37.0 bits (84), Expect = 0.027, Method: Compositional matrix adjust. Identities = 41/157 (26%), Positives = 60/157 (38%), Gaps = 16/157 (10%) Query: 34 LASLPEIKSQG----YHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELPQ 89 L+ LPE + Y L ++R ++ DR D V A+N L PQ Sbjct: 338 LSQLPESAKKALDHRYRSLLPDVRSLKFI---------DRLVADSRVVALNHTAGLSTPQ 388 Query: 90 IKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGLN 149 +V + + + D K + IR E + REL P + PN Y N Sbjct: 389 -QVQMVLFSLFALMDEADAYKQALKQLIRRREATLYRELGMPPLENPNSVNYYTLIDLQN 447 Query: 150 STARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIV 186 T R YGE S W ++ L+ A T I++ Sbjct: 448 VTCRLYGEAFSQ--WAVQQSSTGDMLFRVADETGIVL 482 >4YN3-A nrPDB Length = 621 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 8/79 (10%) Query: 368 VGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFP 427 + PGV IL+ P +G G N ++ GTSM+ PH+TG+ + P Sbjct: 382 ISGPGVEILAAWPSVAPVG--GIRRNT------LFNIISGTSMSCPHITGIATYVKTYNP 433 Query: 428 NAKPWQIRKLLENTAFDFN 446 P I+ L TA N Sbjct: 434 TWSPAAIKSALMTTASPMN 452 >5C3R-A nrPDB Length = 343 Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 6/99 (6%) Query: 34 LASLPEIKSQGYHILFGELRDGEYTE-GKILVGYNDRSEVDKIVKAVNGKVVLELPQIKV 92 L P +KS+ + I G++R GE+T+ G I + + D S VK+ NG+ + P Sbjct: 193 LLHYPAVKSEVFKINPGQVRAGEHTDYGSITLLFQD-SRGGLQVKSPNGQFIDATPIENT 251 Query: 93 VSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKP 131 V + + + + D IK+ R VEP K+E + P Sbjct: 252 VVVNAGDLLARWSNDTIKSTVH---RVVEPP-KQEDVHP 286 >1OFM-A nrPDB Length = 481 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 531 GGPDHWDRALAPYDGESIPGGYAIALRMAEERQASF 566 G P WD + PY + +PG YA+ R++ +R A F Sbjct: 437 GKPLSWDE-VRPYWLKEMPGTYALTARLSADRAAKF 471 >4REV-A nrPDB Length = 164 Score = 29.6 bits (65), Expect = 4.5, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 21/43 (48%) Query: 221 DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDP 263 D Y G + + I A +G + +AP + I++FDDP Sbjct: 20 DILYNGKNAANATSAIVAAPEGVSLTKLAPQSHFGNIIVFDDP 62 >2UXV-A nrPDB Length = 451 Score = 28.9 bits (63), Expect = 7.0, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 455 GYGLVKLDAALQGPLPTQGGVEEFQVVVTDAK-GNFGVP 492 G LV+ + + P+P GV++F V++ D + NFG P Sbjct: 132 GMWLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTP 170 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1R6V-A nrPDB 1088 0.0 3QFH-A nrPDB 288 5e-78 3WHI-A nrPDB 274 1e-73 3VYV-A nrPDB 268 4e-72 1DBI-A nrPDB 265 7e-71 1BH6-A nrPDB 257 1e-68 2E1P-A nrPDB 255 4e-68 1NDQ-A nrPDB 255 8e-68 3A3N-A nrPDB 249 2e-66 1Y3F-E nrPDB 248 5e-66 2WV7-A nrPDB 247 1e-65 4KB5-A nrPDB 245 5e-65 1SCN-E nrPDB 241 9e-64 2IXT-A nrPDB 238 8e-63 5FFN-A nrPDB 236 3e-62 1GNV-A nrPDB 235 4e-62 3LPA-A nrPDB 234 8e-62 3TEC-E nrPDB 231 1e-60 3TI9-A nrPDB 229 2e-60 4LVN-A nrPDB 229 3e-60 4TR2-A nrPDB 228 8e-60 6F9M-A nrPDB 227 1e-59 4HVL-A nrPDB 223 2e-58 5WSL-A nrPDB 222 4e-58 1SH7-A nrPDB 219 3e-57 4H6W-A nrPDB 218 8e-57 2B6N-A nrPDB 217 1e-56 4DZT-A nrPDB 211 8e-55 3I30-X nrPDB 210 2e-54 3F7M-A nrPDB 209 4e-54 3ZXX-A nrPDB 207 1e-53 2GKO-A nrPDB 205 6e-53 5YL7-A nrPDB 198 5e-51 4MZD-A nrPDB 198 7e-51 6F5G-A nrPDB 197 1e-50 3AFG-A nrPDB 196 3e-50 5VLH-A nrPDB 196 4e-50 4K8R-B nrPDB 194 1e-49 4ZOQ-I nrPDB 193 3e-49 5MIM-A nrPDB 190 2e-48 2W2P-A nrPDB 190 2e-48 4KG7-A nrPDB 189 3e-48 2ID4-A nrPDB 189 5e-48 5FAX-A nrPDB 187 1e-47 3F7O-A nrPDB 186 4e-47 1WMD-A nrPDB 184 1e-46 3VV3-A nrPDB 175 7e-44 1V6C-A nrPDB 173 2e-43 5Z6O-A nrPDB 170 2e-42 4H6X-A nrPDB 164 9e-41 3HJR-A nrPDB 162 4e-40 1XF1-A nrPDB 114 1e-25 Sequences not found previously or not previously below threshold: 4BWG-A nrPDB 91 2e-18 4I0W-B nrPDB 86 6e-17 4YN3-A nrPDB 70 2e-12 3I6S-A nrPDB 70 3e-12 1T1E-A nrPDB 54 2e-07 1GA6-A nrPDB 54 3e-07 1SN7-A nrPDB 50 3e-06 1T1I-A nrPDB 49 7e-06 3EDY-A nrPDB 41 0.002 2ZY2-A nrPDB 34 0.35 1VMA-A nrPDB 33 0.49 5C3R-A nrPDB 32 0.67 1OFM-A nrPDB 32 0.75 2BGN-E nrPDB 32 1.1 1QQ9-A nrPDB 31 1.9 3SUC-A nrPDB 31 2.1 4QQ1-A nrPDB 30 3.7 >1R6V-A nrPDB Length = 671 Score = 1088 bits (2813), Expect = 0.0, Method: Composition-based stats. Identities = 670/671 (99%), Positives = 670/671 (99%) Query: 29 SKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELP 88 SKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELP Sbjct: 1 SKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELP 60 Query: 89 QIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGL 148 QIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGL Sbjct: 61 QIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGL 120 Query: 149 NSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY 208 NSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY Sbjct: 121 NSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY 180 Query: 209 RPAFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGG 268 RPAFDEELPAGTDSSYGGS GTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGG Sbjct: 181 RPAFDEELPAGTDSSYGGSAGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGG 240 Query: 269 NGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS 328 NGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS Sbjct: 241 NGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS 300 Query: 329 DSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYE 388 DSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYE Sbjct: 301 DSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYE 360 Query: 389 GHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN 448 GHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN Sbjct: 361 GHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN 420 Query: 449 GWDHDTGYGLVKLDAALQGPLPTQGGVEEFQVVVTDAKGNFGVPTVFVSMMRDNGSCYYA 508 GWDHDTGYGLVKLDAALQGPLPTQGGVEEFQVVVTDAKGNFGVPTVFVSMMRDNGSCYYA Sbjct: 421 GWDHDTGYGLVKLDAALQGPLPTQGGVEEFQVVVTDAKGNFGVPTVFVSMMRDNGSCYYA 480 Query: 509 KTGPDGIARFPHIDSGTYDIFVGGPDHWDRALAPYDGESIPGGYAIALRMAEERQASFVG 568 KTGPDGIARFPHIDSGTYDIFVGGPDHWDRALAPYDGESIPGGYAIALRMAEERQASFVG Sbjct: 481 KTGPDGIARFPHIDSGTYDIFVGGPDHWDRALAPYDGESIPGGYAIALRMAEERQASFVG 540 Query: 569 FGVSPDATQLNVNFNSTLQVKFSTNLSTLKDPQFVVVDPLLRGVYGRVAYARNQTYDLSL 628 FGVSPDATQLNVNFNSTLQVKFSTNLSTLKDPQFVVVDPLLRGVYGRVAYARNQTYDLSL Sbjct: 541 FGVSPDATQLNVNFNSTLQVKFSTNLSTLKDPQFVVVDPLLRGVYGRVAYARNQTYDLSL 600 Query: 629 LSGQISFGIQTLLPAATDITIQGTVTLNGEDIPVYGVLKAGTTWTIIDDFGGLNLGTDSQ 688 LSGQISFGIQTLLPAATDITIQGTVTLNGEDIPVYGVLKAGTTWTIIDDFGGLNLGTDSQ Sbjct: 601 LSGQISFGIQTLLPAATDITIQGTVTLNGEDIPVYGVLKAGTTWTIIDDFGGLNLGTDSQ 660 Query: 689 PIYVWWTIFGQ 699 PIYVWWTIFGQ Sbjct: 661 PIYVWWTIFGQ 671 >3QFH-A nrPDB Length = 447 Score = 288 bits (737), Expect = 5e-78, Method: Composition-based stats. Identities = 99/453 (21%), Positives = 168/453 (37%), Gaps = 87/453 (19%) Query: 64 VGYNDRSEVDKIVKAVNGKVVLELPQIKVVSIKLNGMTVKQAYDKIKALA--LKGIRYVE 121 V Y + + +K+VK + VV +P++ V IK+ M ALA I+Y+ Sbjct: 25 VEYKNTATFNKLVKKKSLNVVYNIPELHVAQIKMTKMHAN-------ALANYKNDIKYIN 77 Query: 122 PSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEA-S 180 + + + R E L + W + I +++ Sbjct: 78 ATCSTCITSEKTID-----------------RTSNESLFSRQWDMNKITNNGASYDDLPK 120 Query: 181 GTNIIVAVVDTGVDGTHPDLEGQV---------IAGYRPAFDEELPAGTDSSYGGSHGTH 231 N +A++DTGV H DL+ + G+R EE D + HGT Sbjct: 121 HANTKIAIIDTGVMKNHDDLKNNFSTDSKNLVPLNGFRGTEPEETGDVHDVNDRKGHGTM 180 Query: 232 VAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKV 291 V+G +A ++GVAP K +F G+ +V+ I+ A + G +V Sbjct: 181 VSGQTSANGK---LIGVAPNNKFTMYRVF-------GSKKTELLWVSKAIVQAANDGNQV 230 Query: 292 MNHSWGGW----------------GYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ-- 333 +N S G + +++A +YA + ++V +AGN+ D + + Sbjct: 231 INISVGSYIILDKNDHQTFRKDEKVEYDALQKAINYAKKKKSIVVAAAGNDGIDVNDKQK 290 Query: 334 ---------------YPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTI-LS 377 PA V+ V + D + F + APG + Sbjct: 291 LKLQREYQGNGEVKDVPASMDNVVTVGSTDQKSNLSEFSNFGMN--YTDIAAPGGSFAYL 348 Query: 378 TVPGEDSI---GYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFP-NAKPWQ 433 G D GY + N G Y Y GTS+A P V+G +A+++ K+ P + Sbjct: 349 NQFGVDKWMNEGYMHKENILTTANNGRYIYQAGTSLATPKVSGALALIIDKYHLEKHPDK 408 Query: 434 IRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 +LL N + G+G + + AL Sbjct: 409 AIELLYQHGTSKNNKPFSR-YGHGELDVYKALN 440 >3WHI-A nrPDB Length = 365 Score = 274 bits (700), Expect = 1e-73, Method: Composition-based stats. Identities = 124/412 (30%), Positives = 176/412 (42%), Gaps = 55/412 (13%) Query: 58 TEGKILVGYNDRSEVDKIVKAVNGKVVLELPQIKVVSIKLNGMTVKQAYDKIKALALKGI 117 TE K +VG+ K + V+S K + + Y A L Sbjct: 6 TEKKYIVGFKQTMSAMSSAKKKD-----------VISEKGGKVQKQFKYVNAAAATLD-- 52 Query: 118 RYVEPSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWE 177 E + K P+V D + + + +G+ I + Sbjct: 53 ---EKAVKELKKDPSVAYVEEDHIAHEYGKPSWLGGGSTQPAQSVPYGISQIKAPALHSQ 109 Query: 178 EASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIA 237 +G+N+ VAV+D+G+D +HPDL + G E D G SHGTHVAGTIA Sbjct: 110 GYTGSNVKVAVIDSGIDSSHPDLNVR---GGASFVPSETNPYQD---GSSHGTHVAGTIA 163 Query: 238 AKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWG 297 A + G++GV+P A + + + D G ++ GI WA + V+N S G Sbjct: 164 ALNNSIGVLGVSPSASLYAVKVLDS------TGSGQYSWIINGIEWAISNNMDVINMSLG 217 Query: 298 GWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ---YPAGYPGVIQVAALDYYGGTF 354 G S +K D A+ G+V+ +AGN S YPA YP I V A++ + Sbjct: 218 GPTGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVN---SSN 274 Query: 355 RVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPH 414 + A FSS + V APGV+I ST+PG GTY Y GT+MA PH Sbjct: 275 QRASFSSAGSELDVMAPGVSIQSTLPG------------------GTYGAYNGTAMATPH 316 Query: 415 VTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 V G A++L K P Q+R LE+TA G G GL+ + AA Q Sbjct: 317 VAGAAALILSKHPTWTNAQVRDRLESTATYL---GNSFYYGKGLINVQAAAQ 365 >3VYV-A nrPDB Length = 275 Score = 268 bits (686), Expect = 4e-72, Method: Composition-based stats. Identities = 109/309 (35%), Positives = 149/309 (48%), Gaps = 39/309 (12%) Query: 161 NELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT 220 + +G+ I + +G+N+ VAV+D+G+D +HPDL + G E Sbjct: 3 SVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVR---GGASFVPSETNPYQ 59 Query: 221 DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAG 280 D G SHGTHVAGTIAA + G++GVAP A + + + D G ++ G Sbjct: 60 D---GSSHGTHVAGTIAALNNSIGVLGVAPSASLYAVKVLDS------TGSGQYSWIING 110 Query: 281 IIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ---YPAG 337 I WA + V+N S GG S +K D A+ G+V+ +AGN S YPA Sbjct: 111 IEWAISNNMDVINMSLGGPTGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAK 170 Query: 338 YPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPAT 397 YP I V A++ + + A FSS + V APGV+I ST+PG Sbjct: 171 YPSTIAVGAVN---SSNQRASFSSVGSELDVMAPGVSIQSTLPG---------------- 211 Query: 398 NGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYG 457 GTY Y GTSMA PHV G A++L K P Q+R LE+TA G G G Sbjct: 212 --GTYGAYNGTSMATPHVAGAAALILSKHPTWTNAQVRDRLESTATYL---GNSFYYGKG 266 Query: 458 LVKLDAALQ 466 L+ + AA Q Sbjct: 267 LINVQAAAQ 275 >1DBI-A nrPDB Length = 280 Score = 265 bits (676), Expect = 7e-71, Method: Composition-based stats. Identities = 114/332 (34%), Positives = 159/332 (47%), Gaps = 56/332 (16%) Query: 136 PNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDG 195 PN Y+ + G +T DY +++ + +AV+DTGVD Sbjct: 3 PNDTYYQGYQYGPQNTYTDYAWDVTKGS------------------SGQEIAVIDTGVDY 44 Query: 196 THPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAA-KKDGKGIVGVAPGAKI 254 THPDL+G+VI GY ++ P +HGTHVAG AA + GI G+AP +I Sbjct: 45 THPDLDGKVIKGYDFVDNDYDP-----MDLNNHGTHVAGIAAAETNNATGIAGMAPNTRI 99 Query: 255 MPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAME 314 + + D NG +A II+A D GA+V+N S G ++ T++ A +YA Sbjct: 100 LAVRALDR------NGSGTLSDIADAIIYAADSGAEVINLSLGCDCHTTTLENAVNYAWN 153 Query: 315 HGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVT 374 G V+V +AGNN S S PA Y VI V A+D Y R+A FS+ V V APGV Sbjct: 154 KGSVVVAAAGNNGS-STTFEPASYENVIAVGAVDQYD---RLASFSNYGTWVDVVAPGVD 209 Query: 375 ILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQI 434 I+ST+ G Y Y GTSMA+PHV G+ A+L + N +I Sbjct: 210 IVSTITGN------------------RYAYMSGTSMASPHVAGLAALLASQGRN--NIEI 249 Query: 435 RKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 R+ +E TA +G G YG + A+ Sbjct: 250 RQAIEQTADKISGTGT--YFKYGRINSYNAVT 279 >1BH6-A nrPDB Length = 274 Score = 257 bits (657), Expect = 1e-68, Method: Composition-based stats. Identities = 103/308 (33%), Positives = 148/308 (48%), Gaps = 40/308 (12%) Query: 162 ELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTD 221 +G+ I + + G N+ V ++DTG+ +H DL +V+ G E Sbjct: 4 VPYGIPLIKADKVQAQGYKGANVKVGIIDTGIASSHTDL--KVVGGASFVSGESYN---- 57 Query: 222 SSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 + G HGTHVAGT+AA + G++GVAP + I + + +G + +GI Sbjct: 58 -TDGNGHGTHVAGTVAALDNTTGVLGVAPNVSLYAIKVLNS------SGSGSYSAIVSGI 110 Query: 282 IWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSA---GNNTSDSHHQYPAGY 338 WAT +G V+N S GG S +K+A D A G+V+V +A GN+ S + YPA Y Sbjct: 111 EWATQNGLDVINMSLGGPSGSTALKQAVDKAYASGIVVVAAAGNSGNSGSQNTIGYPAKY 170 Query: 339 PGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATN 398 VI V A+D A FSS + V APGV++ ST P Sbjct: 171 DSVIAVGAVD---SNKNRASFSSVGSELEVMAPGVSVYSTYPSN---------------- 211 Query: 399 GGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGL 458 TY GTSMA+PHV G A++L K+P Q+R L +TA + G G GL Sbjct: 212 --TYTSLNGTSMASPHVAGAAALILSKYPTLSASQVRNRLSSTATNL---GDSFYYGKGL 266 Query: 459 VKLDAALQ 466 + ++AA Q Sbjct: 267 INVEAAAQ 274 >2E1P-A nrPDB Length = 398 Score = 255 bits (652), Expect = 4e-68, Method: Composition-based stats. Identities = 107/342 (31%), Positives = 147/342 (42%), Gaps = 64/342 (18%) Query: 163 LWGLEAIGVTQQL-WEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTD 221 WG+E + + S + I VAV+DTGVD HPDL + + D Sbjct: 87 PWGIERVKAPSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKLRD 146 Query: 222 SSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 + HGTHV GTIAA + G+VGVAPG +I + + D G +A GI Sbjct: 147 CADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLD------ARGSGSYSDIAIGI 200 Query: 282 IWAT--------------------DHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVV 321 A D A+V++ S GG + + A G+V+V Sbjct: 201 EQAILGPDGVADKDGDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVA 260 Query: 322 SAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPG 381 ++GN + S YPA YP VI V A+D +A FS+R V APGV ILST P Sbjct: 261 ASGNEGAPS-PSYPAAYPEVIAVGAID---SNDNIASFSNRQP--EVSAPGVDILSTYP- 313 Query: 382 EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKF-------------PN 428 +Y+ GT+MA PHV+GVVA++ + + Sbjct: 314 -----------------DDSYETLMGTAMATPHVSGVVALIQAAYYQKYGKILPVGTFDD 356 Query: 429 AKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLP 470 +R +L TA D GWD D GYG+V+ A+Q L Sbjct: 357 ISKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAALG 398 >1NDQ-A nrPDB Length = 269 Score = 255 bits (650), Expect = 8e-68, Method: Composition-based stats. Identities = 101/306 (33%), Positives = 145/306 (47%), Gaps = 39/306 (12%) Query: 161 NELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT 220 + WG+ + +G+ + VAV+DTG+ THPDL + A + P Sbjct: 3 SVPWGISRVQAPAAHNRGLTGSGVKVAVLDTGI-STHPDLNIRGGASFVPGEP------- 54 Query: 221 DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAG 280 + G HGTHVAGTIAA + G++GVAP A++ + + + +A G Sbjct: 55 STQDGNGHGTHVAGTIAALNNSIGVLGVAPSAELYAVKVLGASGSGSVS------SIAQG 108 Query: 281 IIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPG 340 + WA ++G V N S G S T+++A + A GV++V ++GN+ + S YPA Y Sbjct: 109 LEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGAGSI-SYPARYAN 167 Query: 341 VIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGG 400 + V A D A FS G+ + APGV + ST PG Sbjct: 168 AMAVGATDQ---NNNRASFSQYGAGLDIVAPGVNVQSTYPGS------------------ 206 Query: 401 TYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVK 460 TY GTSMA PHV G A++ QK P+ QIR L+NTA G + G GLV Sbjct: 207 TYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSL---GSTNLYGSGLVN 263 Query: 461 LDAALQ 466 +AA + Sbjct: 264 AEAATR 269 >3A3N-A nrPDB Length = 329 Score = 249 bits (637), Expect = 2e-66, Method: Composition-based stats. Identities = 107/342 (31%), Positives = 147/342 (42%), Gaps = 64/342 (18%) Query: 163 LWGLEAIGVTQQL-WEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTD 221 WG+E + + S + I VAV+DTGVD HPDL + + D Sbjct: 18 PWGIERVKAPSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKLRD 77 Query: 222 SSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 + HGTHV GTIAA + G+VGVAPG +I + + D G +A GI Sbjct: 78 CADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLD------ARGSGSYSDIAIGI 131 Query: 282 IWAT--------------------DHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVV 321 A D A+V++ S GG + + A G+V+V Sbjct: 132 EQAILGPDGVADKDGDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVA 191 Query: 322 SAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPG 381 ++GN + S YPA YP VI V A+D +A FS+R V APGV ILST P Sbjct: 192 ASGNEGAPS-PSYPAAYPEVIAVGAID---SNDNIASFSNRQP--EVSAPGVDILSTYP- 244 Query: 382 EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKF-------------PN 428 +Y+ GT+MA PHV+GVVA++ + + Sbjct: 245 -----------------DDSYETLMGTAMATPHVSGVVALIQAAYYQKYGKILPVGTFDD 287 Query: 429 AKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLP 470 +R +L TA D GWD D GYG+V+ A+Q L Sbjct: 288 ISKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAALG 329 >1Y3F-E nrPDB Length = 281 Score = 248 bits (634), Expect = 5e-66, Method: Composition-based stats. Identities = 103/304 (33%), Positives = 144/304 (47%), Gaps = 39/304 (12%) Query: 161 NELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT 220 + +G+ I + +G+N+ VAV+D+G+D +HPDL+ +AG E Sbjct: 3 SVPYGVSQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLK---VAGGASMVPSETNPFQ 59 Query: 221 DSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAG 280 D SHGTHVAGT+AA + G++GVAP A + + + G +G ++ G Sbjct: 60 D---NNSHGTHVAGTVAALNNSIGVLGVAPSASLYAVKVL------GADGSGQYSWIING 110 Query: 281 IIWATDHGAKVMNHSWGGWGYSYTMKEAFDY---AMEHGVVMVVSAGNNTSDSHHQYPAG 337 I WA + V+N S GG S +K A D + V + G + S S YP Sbjct: 111 IEWAIANNMDVINMSLGGPSGSAALKAAVDKAVASGVVVVAAAGNEGTSGSSSTVGYPGK 170 Query: 338 YPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPAT 397 YP VI V A+D + + A FSS + V APGV+I ST+PG Sbjct: 171 YPSVIAVGAVD---SSNQRASFSSVGPELDVMAPGVSIQSTLPGNK-------------- 213 Query: 398 NGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYG 457 Y Y GTSMA+PHV G A++L K PN Q+R LENT G G G Sbjct: 214 ----YGAYNGTSMASPHVAGAAALILSKHPNWTNTQVRSSLENTTTKL---GDSFYYGKG 266 Query: 458 LVKL 461 L+ + Sbjct: 267 LINV 270 >2WV7-A nrPDB Length = 329 Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats. Identities = 95/339 (28%), Positives = 141/339 (41%), Gaps = 43/339 (12%) Query: 154 DYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFD 213 D LS G+E + A G I+ V+DTG HPDL ++I G D Sbjct: 13 DKVSALSEVPMGVEIVEAPAVWRASAKGAGQIIGVIDTGCQVDHPDLAERIIGGVNLTTD 72 Query: 214 EELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVG 273 T+ S HGTHVAGT+AA + G G+VGVAP A + I G+G Sbjct: 73 -YGGDETNFSDNNGHGTHVAGTVAAAETGSGVVGVAPKADLFIIKAL------SGDGSGE 125 Query: 274 DDYVAAGIIWATD------HGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNT 327 ++A I +A D +++ S GG S + +A YA+ + V +V +AGN Sbjct: 126 MGWIAKAIRYAVDWRGPKGEQMRIITMSLGGPTDSEELHDAVKYAVSNNVSVVCAAGNEG 185 Query: 328 SD----SHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGED 383 + YPA Y VI V A+D+ R++ F++ ++ + + APGV I ST Sbjct: 186 DGREDTNEFAYPAAYNEVIAVGAVDFD---LRLSDFTNTNEEIDIVAPGVGIKSTYL--- 239 Query: 384 SIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPN-----AKPWQIRKLL 438 Y GT+MAAPHV G +A+++ + +I L Sbjct: 240 ---------------DSGYAELSGTAMAAPHVAGALALIINLAEDAFKRSLSETEIYAQL 284 Query: 439 ENTAFDFNGNGWDHDTGYGLVKLDAALQGPLPTQGGVEE 477 A G+ + L + G +G E Sbjct: 285 VRRATPIGFTAQAEGNGFLTLDLVERITGQFTEKGKKLE 323 >4KB5-A nrPDB Length = 408 Score = 245 bits (625), Expect = 5e-65, Method: Composition-based stats. Identities = 99/401 (24%), Positives = 158/401 (39%), Gaps = 80/401 (19%) Query: 121 EPSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEAS 180 +P+ +R++ V PN ++ W + + + Q+ + A+ Sbjct: 21 QPTEQRKICATPTVMPN-------------------SNFADRPWANDYLRI-QEAQKFAT 60 Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK 240 G + VAV+DTGV+G+ P + + P D AG S +HGT A I + Sbjct: 61 GAGVTVAVIDTGVNGS-PRVPAE------PGGDFVDAAGNGMSDCDAHGTMTAAIIGGRP 113 Query: 241 DG-KGIVGVAPGAKIMPIV----------IFDDPALVGGNGYVGD-DYVAAGIIWATDHG 288 G VG+AP +++ + DP G +A ++ A + G Sbjct: 114 SPTDGFVGMAPDVRLLSLRQTSVAFQPKGARQDPNDPNTTQTAGSIRSLARSVVHAANLG 173 Query: 289 AKVMNHSWGGW------GYSYTMKEAFDYAME-HGVVMVVSAGNNTSDSHHQ-------- 333 A+V+N S ++ A +YA+ G V+VV+AGN D Sbjct: 174 AQVINISEAACYKVTRRIDETSLGAAINYAVNVKGAVIVVAAGNTGQDCSQNPPPDPSVP 233 Query: 334 -------------YPAGY-PGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTV 379 PA Y P V+ V ++ G + FS V APG + S Sbjct: 234 SDPRGWREVQTIVSPAWYDPLVLTVGSIGQNGQP---SNFSMSGPWVGAAAPGENLTS-- 288 Query: 380 PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLE 439 +GY+G N G GTS +A +V+G+ A++ Q+FP+ P QI + Sbjct: 289 -----LGYDGQPVNATPGEDGPVP-LNGTSFSAAYVSGLAALVKQRFPDLTPAQIINRIT 342 Query: 440 NTAFDFNGNGWDHDTGYGLVKLDAALQGPLPTQGGVEEFQV 480 TA G G D+ G G++ AAL +P F+V Sbjct: 343 ATARH-PGGGVDNYVGAGVIDPVAALTWEIPDGPEKAPFRV 382 >1SCN-E nrPDB Length = 276 Score = 241 bits (614), Expect = 9e-64, Method: Composition-based stats. Identities = 105/310 (33%), Positives = 142/310 (45%), Gaps = 40/310 (12%) Query: 162 ELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTD 221 +G+ I + + G N+ VAV+DTG+ +HPDL V+ G E Sbjct: 4 VPYGIPLIKADKVQAQGFKGANVKVAVLDTGIQASHPDL--NVVGGASFVAGEAYN---- 57 Query: 222 SSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 + G HGTHVAGT+AA + G++GVAP + + + + +G V GI Sbjct: 58 -TDGNGHGTHVAGTVAALDNTTGVLGVAPSVSLYAVKVLNSSGSGSYSGIVS------GI 110 Query: 282 IWATDHGAKVMNHSWGGWGYSYTMKEAFDYAM---EHGVVMVVSAGNNTSDSHHQYPAGY 338 WAT +G V+N S GG S MK+A D A V ++GN+ S + YPA Y Sbjct: 111 EWATTNGMDVINMSLGGASGSTAMKQAVDNAYARGVVVVAAAGNSGNSGSTNTIGYPAKY 170 Query: 339 PGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATN 398 VI V A+D A FSS + V APG + ST P Sbjct: 171 DSVIAVGAVD---SNSNRASFSSVGAELEVMAPGAGVYSTYPTN---------------- 211 Query: 399 GGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGL 458 TY GTSMA+PHV G A++L K PN Q+R L +TA G G GL Sbjct: 212 --TYATLNGTSMASPHVAGAAALILSKHPNLSASQVRNRLSSTATYL---GSSFYYGKGL 266 Query: 459 VKLDAALQGP 468 + ++AA Q P Sbjct: 267 INVEAAAQAP 276 >2IXT-A nrPDB Length = 310 Score = 238 bits (606), Expect = 8e-63, Method: Composition-based stats. Identities = 99/329 (30%), Positives = 141/329 (42%), Gaps = 54/329 (16%) Query: 163 LWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDS 222 WG++AI L G+ I +AV+DTGV+ +HPDL V P Sbjct: 7 PWGIKAIYNNDTLTSTTGGSGINIAVLDTGVNTSHPDLVNNVEQCKDFT-GATTPINNSC 65 Query: 223 SYGGSHGTHVAGTIAAKKDGK--GIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAG 280 + HGTHVAGT A GI GVAP A + + D +G D +AA Sbjct: 66 TDRNGHGTHVAGTALADGGSDQAGIYGVAPDADLWAYKVLLD------SGSGYSDDIAAA 119 Query: 281 IIWATDHGA-----KVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNT-SDSHHQY 334 I A D +++ S G + + A +YA GV++V +AGN+ S Y Sbjct: 120 IRHAADQATATGTKTIISMSLGSSANNSLISSAVNYAYSKGVLIVAAAGNSGYSQGTIGY 179 Query: 335 PAGYPGVIQVAALD--YYGGTFRVAGFSSRSD------------GVSVGAPGVTILSTVP 380 P P I VAAL+ GT+RVA +SSR + + APG ++ ST Sbjct: 180 PGALPNAIAVAALENVQQNGTYRVADYSSRGYISTAGDYVIQEGDIEISAPGSSVYSTWY 239 Query: 381 GEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLEN 440 G Y+ GTSMA PHV+G+ A + + P+ Q+R L+ Sbjct: 240 ------------------NGGYNTISGTSMATPHVSGLAAKIWAENPSLSNTQLRSNLQE 281 Query: 441 TAF--DFNGN-----GWDHDTGYGLVKLD 462 A D G G D+ +G+G ++ Sbjct: 282 RAKSVDIKGGYGAAIGDDYASGFGFARVQ 310 >5FFN-A nrPDB Length = 311 Score = 236 bits (601), Expect = 3e-62, Method: Composition-based stats. Identities = 103/331 (31%), Positives = 150/331 (45%), Gaps = 54/331 (16%) Query: 160 SNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAG 219 + WG+++I Q + + G+ I VAV+DTGV +H DL G L G Sbjct: 5 TQTPWGIKSIYNDQSITKTTGGSGIKVAVLDTGVYTSHLDLAGSAEQCKDFTQSNPLVDG 64 Query: 220 TDSSYGGSHGTHVAGTIAAK--KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYV 277 + + HGTHVAGT+ A +G+G+ GVAP AK+ + D NG D + Sbjct: 65 S-CTDRQGHGTHVAGTVLAHGGSNGQGVYGVAPQAKLWAYKVLGD------NGSGYSDDI 117 Query: 278 AAGIIWATDHGAK-----VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH 332 AA I D ++ V+N S G + A DYA GV++V +AGN+ S S+ Sbjct: 118 AAAIRHVADEASRTGSKVVINMSLGSSAKDSLIASAVDYAYGKGVLIVAAAGNSGSGSNT 177 Query: 333 -QYPAGYPGVIQVAALD--YYGGTFRVAGFSSRSD------------GVSVGAPGVTILS 377 +P G + VAAL+ GT+RVA FSSR + + V APG ++ S Sbjct: 178 IGFPGGLVNAVAVAALENVQQNGTYRVADFSSRGNPATAGDYIIQERDIEVSAPGASVES 237 Query: 378 TVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKL 437 T G Y+ GTSMA PHV G+ A + + Q+R Sbjct: 238 TWYT------------------GGYNTISGTSMATPHVAGLAAKIWSANTSLSHSQLRTE 279 Query: 438 LENTAFDF-------NGNGWDHDTGYGLVKL 461 L+N A + G G D+ +G+G ++ Sbjct: 280 LQNRAKVYDIKGGIGAGTGDDYASGFGYPRV 310 >1GNV-A nrPDB Length = 266 Score = 235 bits (600), Expect = 4e-62, Method: Composition-based stats. Identities = 102/308 (33%), Positives = 139/308 (45%), Gaps = 48/308 (15%) Query: 162 ELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTD 221 +G+ I + +G+N+ VAV+D+G+D +HPDL +AG E D Sbjct: 4 VSYGVSQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLN---VAGGASFVPSETNPFQD 60 Query: 222 SSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 SHGTHVAGT+ A VAP A + + + G +G ++ GI Sbjct: 61 ---NNSHGTHVAGTVLA---------VAPSASLYAVKVL------GADGSGQYSWIINGI 102 Query: 282 IWATDHGAKVMNHSWGGWGYSYTMKEAFDY---AMEHGVVMVVSAGNNTSDSHHQYPAGY 338 WA + V+N S GG S +K A D + V + G + S S YP Y Sbjct: 103 EWAIANNMDVINMSLGGPSGSAALKAAVDKAVASGVVVVAAAGNEGTSGSSSTVGYPGKY 162 Query: 339 PGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATN 398 P VI V A+D + + A FSS + V APGV+I ST+PG Sbjct: 163 PSVIAVGAVD---SSNQRASFSSVGPELDVMAPGVSICSTLPGNK--------------- 204 Query: 399 GGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGL 458 Y GTSMA+PHV G A++L K PN Q+R LENT G G GL Sbjct: 205 ---YGAKSGTSMASPHVAGAAALILSKHPNWTNTQVRSSLENTTTKL---GDSFYYGKGL 258 Query: 459 VKLDAALQ 466 + ++AA Q Sbjct: 259 INVEAAAQ 266 >3LPA-A nrPDB Length = 340 Score = 234 bits (598), Expect = 8e-62, Method: Composition-based stats. Identities = 106/354 (29%), Positives = 153/354 (43%), Gaps = 55/354 (15%) Query: 156 GEELSNELWG-LEAIGVT-QQLWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPA- 211 ++ E W + GV ++W+ +G N++VAVVDTG+ H DL V+ GY Sbjct: 3 NDQHYREQWHYFDRYGVKADKVWDMGFTGQNVVVAVVDTGI-LHHRDLNANVLPGYDFIS 61 Query: 212 ---------------------FDEELPAG-----TDSSYGGSHGTHVAGTIAA-KKDGKG 244 FD G + S HG+HVAGTIAA + G Sbjct: 62 NSQISLDGDGRDADPFDEGDWFDNWACGGYPDPRKERSDSSWHGSHVAGTIAAVTNNRIG 121 Query: 245 IVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWAT---DHGAKVMNHSWGGWG- 300 + GVA GAK++P+ + G + A G I + AKV+N S G G Sbjct: 122 VAGVAYGAKVVPVRALGRCGGYDSDISDGLYWAAGGRIAGIPENRNPAKVINMSLGSDGQ 181 Query: 301 YSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFS 360 SY + D A G ++VV+AGN ++ + +P V+ V A G A FS Sbjct: 182 CSYNAQTMIDRATRLGALVVVAAGNENQNASNTWPTSCNNVLSVGATTSRGI---RASFS 238 Query: 361 SRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVA 420 + V + APG ILSTV + Y + GTSMA PHV+GV A Sbjct: 239 NYGVDVDLAAPGQDILSTV-----------DSGTRRPVSDAYSFMAGTSMATPHVSGVAA 287 Query: 421 VLLQK----FPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLP 470 +++ N P +++ +L +T FNG D G G+V +AA+ L Sbjct: 288 LVISAANSVNKNLTPAELKDVLVSTTSPFNGR-LDRALGSGIVDAEAAVNSVLG 340 >3TEC-E nrPDB Length = 279 Score = 231 bits (588), Expect = 1e-60, Method: Composition-based stats. Identities = 106/309 (34%), Positives = 145/309 (46%), Gaps = 39/309 (12%) Query: 159 LSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 S+ +G + I Q W+ A G+ +A+VDTGV HPDL G+V+ G+ ++ P Sbjct: 8 FSSRQYGPQKIQAPQ-AWDIAEGSGAKIAIVDTGVQSNHPDLAGKVVGGWDFVDNDSTPQ 66 Query: 219 GTDSSYGGSHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYV 277 G HGTH AG AA + GI G AP A I+ + + D+ +G V Sbjct: 67 N-----GNGHGTHCAGIAAAVTNNSTGIAGTAPKASILAVRVLDN------SGSGTWTAV 115 Query: 278 AAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAG 337 A GI +A D GAKV++ S GG + +++A +YA G V+V +AG N ++ YPA Sbjct: 116 ANGITYAADQGAKVISLSLGGTVGNSGLQQAVNYAWNKGSVVVAAAG-NAGNTAPNYPAY 174 Query: 338 YPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPAT 397 Y I VA+ D + FS+ V V APG I ST P Sbjct: 175 YSNAIAVASTDQ---NDNKSSFSTYGSVVDVAAPGSWIYSTYPTS--------------- 216 Query: 398 NGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYG 457 TY GTSMA PHV GV +L + +A IR +ENTA +G G G Sbjct: 217 ---TYASLSGTSMATPHVAGVAGLLASQGRSASN--IRAAIENTADKISGTGT--YWAKG 269 Query: 458 LVKLDAALQ 466 V A+Q Sbjct: 270 RVNAYKAVQ 278 >3TI9-A nrPDB Length = 352 Score = 229 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 96/337 (28%), Positives = 143/337 (42%), Gaps = 53/337 (15%) Query: 173 QQLWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGG----- 226 ++W+ +G ++V+VVDTG+ H DL G ++ GY D Sbjct: 23 DKVWDRGFTGQGVVVSVVDTGI-LDHVDLNGNMLPGYDFISSAPKARDGDQRDNNPADEG 81 Query: 227 ----------------------SHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDP 263 HG+HVAGTIAA +G G+ GVA GAK++P+ + Sbjct: 82 DWFDNWDCGGYPDPRREKRFSTWHGSHVAGTIAAVTNNGVGVAGVAYGAKVIPVRVLGKC 141 Query: 264 ALVGGNGYVGDDYVAAGIIWAT---DHGAKVMNHSWGGWG-YSYTMKEAFDYAMEHGVVM 319 + G + A G I + A+V+N S GG G S + + D G ++ Sbjct: 142 GGYDSDITDGMYWSAGGHIDGVPDNQNPAQVINMSLGGDGDCSQSSQRIIDKTTNLGALI 201 Query: 320 VVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTV 379 V++AGN D+ +P+ V+ V A G A FS+ V + APG ILST+ Sbjct: 202 VIAAGNENQDASRTWPSSCNNVLSVGATTPKGK---RAPFSNYGARVHLAAPGTNILSTI 258 Query: 380 PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQK----FPNAKPWQIR 435 + +Y GTSMAAPHV+GV A+++ P ++ Sbjct: 259 -----------DVGQAGPVRSSYGMKAGTSMAAPHVSGVAALVISAANSIGKTLTPSELS 307 Query: 436 KLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLPTQ 472 +L T FNG D G G+V +AA+ L Q Sbjct: 308 DILVRTTSRFNGR-LDRGLGSGIVDANAAVNAVLGDQ 343 >4LVN-A nrPDB Length = 344 Score = 229 bits (584), Expect = 3e-60, Method: Composition-based stats. Identities = 83/357 (23%), Positives = 138/357 (38%), Gaps = 68/357 (19%) Query: 155 YGEELSNELWGLE--AIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAG----- 207 + +E N WGL+ + TQ+L E + + V+D+G+D HPDL+ + Sbjct: 8 FNDEFRNLQWGLDLSRLDETQELINEHQVMSTRICVIDSGIDYNHPDLKDNIELNLKELH 67 Query: 208 YRPAFDEELPAGTDSSYG-------------GSHGTHVAGTIAA-KKDGKGIVGVAPGAK 253 R FD++ D YG HGTHV+G I+A + G+VGV +K Sbjct: 68 GRKGFDDDNNGIVDDIYGANFVNNSGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVNSK 127 Query: 254 IMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAM 313 ++ D+ L G +GD + + + A ++N S+ YS + +Y Sbjct: 128 LIICKALDEHKL----GRLGDMFKC--LDYCISRNAHMINGSFSFDEYSGIFNSSVEYLQ 181 Query: 314 EHGVVMVVSAGNNTSDSHHQ-------------YP----AGYPGVIQVAALDYYGGTFRV 356 G++ VSA N + YP Y VI VA L Sbjct: 182 RKGILFFVSASNCSHPKSSTPDIRKCDLSINAKYPPILSTVYDNVISVANLKKNDNNNHY 241 Query: 357 A----GFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAA 412 + F S + APG I ST P +Y GTSMAA Sbjct: 242 SLSINSFYSNK-YCQLAAPGTNIYSTAPHN------------------SYRKLNGTSMAA 282 Query: 413 PHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPL 469 PHV + +++ P+ ++ ++L+++ + + G ++ A+ + Sbjct: 283 PHVAAIASLIFSINPDLSYKKVIQILKDSIVYL-PSLKNMVAWAGYADINKAVNLAI 338 >4TR2-A nrPDB Length = 663 Score = 228 bits (580), Expect = 8e-60, Method: Composition-based stats. Identities = 90/356 (25%), Positives = 135/356 (37%), Gaps = 67/356 (18%) Query: 155 YGEELSNELWGLE--AIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAG----- 207 + +E N WGL+ + TQ L + + V+D+G+D HPDL + Sbjct: 295 FNDEYRNLQWGLDLARLDETQDLINANRVSVTKICVIDSGIDYNHPDLRNNIDVNVKELH 354 Query: 208 YRPAFDEELPAGTDSSYG-------------GSHGTHVAGTIAAK-KDGKGIVGVAPGAK 253 R D++ D YG HGTHV+G I+A +G GIVGV +K Sbjct: 355 GRKGVDDDSNGVVDDVYGANFVNNSGDPMDDNYHGTHVSGIISAVGNNGIGIVGVDGHSK 414 Query: 254 IMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAM 313 ++ D L G +GD + I + A ++N S+ YS + ++ Sbjct: 415 LVICKALDQHKL----GRLGDMFKC--IDYCISRQAHMINGSFSFDEYSNIFNASVEHLR 468 Query: 314 EHGVVMVVSAGNNTSDS-------------HHQYPA----GYPGVIQVAALDYY---GGT 353 G++ VSA N D +H+YP + VI VA L + Sbjct: 469 SLGILFFVSASNCAHDKLSKPDIAKCDLAVNHRYPPILSKTHNNVIAVANLKRDLDESYS 528 Query: 354 FRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAP 413 V F S + APG I ST P + Y GTSMA+P Sbjct: 529 LSVNSFYSNI-YCQLAAPGTNIYSTTPMNN------------------YRKLNGTSMASP 569 Query: 414 HVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPL 469 HV + +++ PN QI ++L N G G V + A+ + Sbjct: 570 HVAAIASIVRSINPNLTYLQIVEILRNAIVKLPSLTERVSWG-GYVDILRAVNLAI 624 >6F9M-A nrPDB Length = 330 Score = 227 bits (579), Expect = 1e-59, Method: Composition-based stats. Identities = 91/316 (28%), Positives = 135/316 (42%), Gaps = 46/316 (14%) Query: 163 LWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDS 222 G+ I + G +VAV+DTG HPDL ++ G D+ Sbjct: 22 PEGVRMIQAPELWESAEHGKGNVVAVLDTGCQTDHPDLTARIAGGRNFTHDDGGDPERFE 81 Query: 223 SYGGSHGTHVAGTIAAK-KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGI 281 Y HGTHVAGT+AA +D +G+VGVAP A ++ + + D G + + AGI Sbjct: 82 DY-NGHGTHVAGTVAASLRDEEGVVGVAPLADLLVVKVLDKE------GSGSYEGIIAGI 134 Query: 282 IWATD------HGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ-- 333 +A D V++ S GG + EA A++ G+ ++ +AGN D+H Sbjct: 135 HYAIDWRGPEGQKTTVISMSLGGPEDHPELYEAVKRAVDAGIPVICAAGNEGDDAHDTDE 194 Query: 334 --YPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHN 391 YP Y VIQV A+D+ R+A FS+ ++ + + APG+ I ST Sbjct: 195 FAYPGAYGEVIQVGAVDFDR---RIAPFSNTNNEIDLVAPGINIYSTYL----------- 240 Query: 392 ENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFP-----NAKPWQIRKLLENTAFDFN 446 G Y GTSMA PHV+G +A++ ++ L Sbjct: 241 -------EGKYASLSGTSMATPHVSGALALIRNISEREFDRELTEAELYAQLVRRTIPL- 292 Query: 447 GNGWDHDTGYGLVKLD 462 G GL+ LD Sbjct: 293 -GYPKTAEGNGLLALD 307 >4HVL-A nrPDB Length = 377 Score = 223 bits (568), Expect = 2e-58, Method: Composition-based stats. Identities = 100/388 (25%), Positives = 154/388 (39%), Gaps = 68/388 (17%) Query: 128 LIKPTVVKPNPD-----MYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEASGT 182 +I P V P+ M + R + D ++ W + + +T + + A+G Sbjct: 6 VIDPAAVPPDETGPDNPMEQRRVCAAPTVYPD--SNFADRPWASDYLRLT-EAHKFATGA 62 Query: 183 NIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK-KD 241 I VAV+DTGV+G+ P + + P D AG S +HGT A IA + Sbjct: 63 GITVAVIDTGVNGS-PRVPAE------PGGDFVDAAGNGMSDCDAHGTLTASVIAGRGAP 115 Query: 242 GKGIVGVAPGAKIM----------PIVIFDDPALVGGNGYVGDD-YVAAGIIWATDHGAK 290 G +GVAP A+I+ P+ DP G +A I+ A + GA+ Sbjct: 116 TDGFIGVAPDARILSLRHTSAAFQPVGARTDPNNPNTTQTAGSLRSLARAIVHAANLGAQ 175 Query: 291 VMNHSWGG------WGYSYTMKEAFDYAME-HGVVMVVSAGNNTSDSHHQ---------- 333 V+N S + A +YA+ V++ +AGN D Sbjct: 176 VINISEAACYKVTRPIDETGVGAAVNYAVHVKNAVVIAAAGNTGQDCTQNPPPDPAVPSD 235 Query: 334 -----------YPAGY-PGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPG 381 PA Y P V+ V + G T + + FS V AP I + Sbjct: 236 PRGWQQVQTIVSPAWYSPLVLTVGGI---GPTGQPSNFSMSGPWVGAAAPAENITA---- 288 Query: 382 EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENT 441 +GY G N G GTS AA +V+G+ A++ Q++P+ P Q+ + T Sbjct: 289 ---LGYGGEPVNALQGQDGLVP-VAGTSFAAAYVSGLAALIRQRYPDLTPAQVINRITAT 344 Query: 442 AFDFNGNGWDHDTGYGLVKLDAALQGPL 469 A G G D+ G G++ AAL + Sbjct: 345 ARH-PGGGVDNYVGAGVIDPVAALTWDV 371 >5WSL-A nrPDB Length = 299 Score = 222 bits (566), Expect = 4e-58, Method: Composition-based stats. Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 43/292 (14%) Query: 160 SNELWGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDE 214 + WGL+ I ++ +G+ + ++DTG+ +H + G+ A + + Sbjct: 4 TGATWGLDRIDQRTLPLSGTFTYSNTGSGVNAYIIDTGIRVSHSEFGGRATAVF-----D 58 Query: 215 ELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD 274 + G + + HGTHVAGT+ + GVA ++ + + + +G + Sbjct: 59 AIGDGQNGNDCNGHGTHVAGTVGGT-----VYGVAKSVRLYAVRVLN------CSGSGSN 107 Query: 275 DYVAAGIIWATDHGAK--VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH 332 V AG+ W + + V N S GG G S + A + A+ G+ ++AGN+ D+ Sbjct: 108 SGVIAGVDWVRQNARRPAVANMSLGG-GASSALDTAVNNAINAGITFALAAGNSNRDACQ 166 Query: 333 QYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNE 392 PA I V A T A +S+ + + APG +I S D+ Sbjct: 167 FSPARVTAGITVGATT---STDARASYSNYGSCLDLFAPGSSITSAWISSDT-------- 215 Query: 393 NVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFD 444 + + GTSMA PHV GV A+ LQ P+A P +R + A Sbjct: 216 --------STNTISGTSMATPHVAGVAALYLQSNPSASPATVRNAIVGNATS 259 >1SH7-A nrPDB Length = 284 Score = 219 bits (558), Expect = 3e-57, Method: Composition-based stats. Identities = 83/292 (28%), Positives = 124/292 (42%), Gaps = 45/292 (15%) Query: 160 SNELWGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDE 214 SN +WGL+ I + + G + V+DTGV+ H + G+ ++GY ++ Sbjct: 2 SNAIWGLDRIDQRNLPLDRNYNANFDGFGVTAYVIDTGVNNNHEEFGGRSVSGYDFVDND 61 Query: 215 ELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD 274 DSS HGTHVAGTI + GVA I+ + + +G Sbjct: 62 A-----DSSDCNGHGTHVAGTIGGSQ-----YGVAKNVNIVGVRVL------SCSGSGTT 105 Query: 275 DYVAAGIIWATDH--GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH 332 V +G+ W + G V N S GG G S + A A++ GV +++AGN+ +D+ + Sbjct: 106 SGVISGVDWVAQNASGPSVANMSLGG-GQSTALDSAVQGAIQSGVSFMLAAGNSNADACN 164 Query: 333 QYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNE 392 PA P + V + + + S V + APG I S Sbjct: 165 TSPARVPSGVTVGSTTSSDSRSSFSNWGS---CVDLFAPGSQIKSAWY------------ 209 Query: 393 NVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFD 444 G Y GTSMA PHV GV A+ LQ+ P Q+ LL + A + Sbjct: 210 ------DGGYKTISGTSMATPHVAGVAALYLQENNGLTPLQLTGLLNSRASE 255 >4H6W-A nrPDB Length = 306 Score = 218 bits (554), Expect = 8e-57, Method: Composition-based stats. Identities = 77/306 (25%), Positives = 123/306 (40%), Gaps = 37/306 (12%) Query: 166 LEAIGVTQQLWEEASGT-NIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSY 224 + I ++LW E G I VAV+D VD HP G + E A S Sbjct: 4 MTNIPGLKKLWSETRGDPKICVAVLDGIVDQNHPCFIGADLTRLPSLVSGEANANGSMS- 62 Query: 225 GGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWA 284 +HGTHVA I + D + G+AP + + + +F D +L + ++ I A Sbjct: 63 --THGTHVASIIFGQHDSP-VTGIAPQCRGLIVPVFADESL-----KLSQLDLSRAIEQA 114 Query: 285 TDHGAKVMNHSWG----GWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPG 340 ++GA ++N S G +++A E+ V+++ + GN+ + PA P Sbjct: 115 VNNGANIINVSAGQLTDAGEADTWLEKAIQLCQENNVLLIAATGNDGCE-CLHVPASLPT 173 Query: 341 VIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGG 400 V+ V A+D G + + + APG IL P G Sbjct: 174 VLAVGAMDDQGKPVDFSNWGDAYQKQGILAPGKDILGAKP------------------NG 215 Query: 401 TYDYYQGTSMAAPHVTGVVAVLLQ----KFPNAKPWQIRKLLENTAFDFNGNGWDHDTGY 456 GTS A P V+GV A+LL + P +++ L +A N D + Sbjct: 216 GTIRLSGTSFATPIVSGVAALLLSLQIKRGEKPDPQKVKNALLASATPCNPKDTDDQSRC 275 Query: 457 GLVKLD 462 + KL+ Sbjct: 276 LMGKLN 281 >2B6N-A nrPDB Length = 278 Score = 217 bits (553), Expect = 1e-56, Method: Composition-based stats. Identities = 81/287 (28%), Positives = 127/287 (44%), Gaps = 43/287 (14%) Query: 164 WGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WG++ I + + G+ + V+DTGV TH + G+ +GY ++ Sbjct: 8 WGIDRIDQRNLPLDNNYHTDYDGSGVTAFVIDTGVLNTHNEFGGRASSGYDFIDNDY--- 64 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 D++ HGTHVAGTI GVA ++ + + + +G + V Sbjct: 65 --DATDCNGHGTHVAGTIGGS-----TYGVAKNVNVVGVRVLN------CSGSGSNSGVI 111 Query: 279 AGIIWATDH--GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPA 336 AGI W ++ G V N S GG G S +A + A+ G+ VV+AGN+ S++ + PA Sbjct: 112 AGINWVKNNASGPAVANMSLGG-GASQATDDAVNAAVAAGITFVVAAGNDNSNACNYSPA 170 Query: 337 GYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPA 396 I V + + FS+ + + APG +I S+ +S Sbjct: 171 RAADAITVGSTT---SNDSRSSFSNYGTCLDIYAPGSSITSSWYTSNS------------ 215 Query: 397 TNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAF 443 + GTSMA+PHV GV A+ L + PN P Q+ LL+ A Sbjct: 216 ----ATNTISGTSMASPHVAGVAALYLDENPNLSPAQVTNLLKTRAT 258 >4DZT-A nrPDB Length = 276 Score = 211 bits (537), Expect = 8e-55, Method: Composition-based stats. Identities = 84/291 (28%), Positives = 121/291 (41%), Gaps = 45/291 (15%) Query: 160 SNELWGLEAIG-----VTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDE 214 S WGL+ I ++ A+G + V V+DTG+ TH + G+ GY Sbjct: 4 SPAPWGLDRIDQRDLPLSNSYTYTATGRGVNVYVIDTGIRTTHREFGGRARVGY------ 57 Query: 215 ELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD 274 G + HGTHVAGTI GVA + + + D NG Sbjct: 58 -DALGGNGQDCNGHGTHVAGTIGGV-----TYGVAKAVNLYAVRVLD------CNGSGST 105 Query: 275 DYVAAGIIWATDHGAK--VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH 332 V AG+ W T + + V N S GG G S + A ++ GVV V+AGN+ +++ + Sbjct: 106 SGVIAGVDWVTRNHRRPAVANMSLGG-GVSTALDNAVKNSIAAGVVYAVAAGNDNANACN 164 Query: 333 QYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNE 392 PA + V A + A FS+ V + APG +I S D+ Sbjct: 165 YSPARVAEALTVGATT---SSDARASFSNYGSCVDLFAPGASIPSAWYTSDT-------- 213 Query: 393 NVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAF 443 GTSMA PHV GV A+ L++ P+A P + + N A Sbjct: 214 --------ATQTLNGTSMATPHVAGVAALYLEQNPSATPASVASAILNGAT 256 >3I30-X nrPDB Length = 279 Score = 210 bits (534), Expect = 2e-54, Method: Composition-based stats. Identities = 89/310 (28%), Positives = 130/310 (41%), Gaps = 46/310 (14%) Query: 160 SNELWGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDE 214 +N WGL I G + ++E++G V V+DTG++ +HP+ EG+ Sbjct: 4 TNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQM-------- 55 Query: 215 ELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYV-G 273 S G HGTH AGT+ G GVA ++ + + DD + + G Sbjct: 56 VKTYYYSSRDGNGHGTHCAGTV-----GSRTYGVAKKTQLFGVKVLDDNGSGQYSTIIAG 110 Query: 274 DDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ 333 D+VA+ V + S GG GYS ++ A GV++ V+AGNN +D+ + Sbjct: 111 MDFVASDKNNRNCPKGVVASLSLGG-GYSSSVNSAAARLQSSGVMVAVAAGNNNADARNY 169 Query: 334 YPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNEN 393 PA P V V A D Y R + FS+ + + PG +ILST G Sbjct: 170 SPASEPSVCTVGASDRYD---RRSSFSNYGSVLDIFGPGTSILSTWIG------------ 214 Query: 394 VPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHD 453 G+ GTSMA PHV G+ A L+ R + D G + Sbjct: 215 ------GSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACRYI-----ADTANKGDLSN 263 Query: 454 TGYGLVKLDA 463 +G V L A Sbjct: 264 IPFGTVNLLA 273 >3F7M-A nrPDB Length = 279 Score = 209 bits (531), Expect = 4e-54, Method: Composition-based stats. Identities = 84/266 (31%), Positives = 113/266 (42%), Gaps = 41/266 (15%) Query: 164 WGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WGL I G T ++ ++G V V+DTGV+ THPD EG+ A Sbjct: 9 WGLTRISHRARGSTAYAYDTSAGAGACVYVIDTGVEDTHPDFEGRAKQIKSYA------- 61 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVG-GNGYVGDDYV 277 + + G HGTH AGTI +K GVA I + + DD N G D+V Sbjct: 62 -STARDGHGHGTHCAGTIGSK-----TWGVAKKVSIFGVKVLDDSGSGSLSNIIAGMDFV 115 Query: 278 AAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAG 337 A+ V + S GG GYS + +A GV + V+AGN+ D+ + PA Sbjct: 116 ASDRQSRNCPRRTVASMSLGG-GYSAALNQAAARLQSSGVFVAVAAGNDNRDAANTSPAS 174 Query: 338 YPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPAT 397 P V V A D + FS+ V + APG +I ST G Sbjct: 175 EPTVCTVGATD---SNDVRSTFSNYGRVVDIFAPGTSITSTWIG---------------- 215 Query: 398 NGGTYDYYQGTSMAAPHVTGVVAVLL 423 G + GTSMA PH+ G+ A L Sbjct: 216 --GRTNTISGTSMATPHIAGLAAYLF 239 >3ZXX-A nrPDB Length = 307 Score = 207 bits (527), Expect = 1e-53, Method: Composition-based stats. Identities = 80/307 (26%), Positives = 127/307 (41%), Gaps = 42/307 (13%) Query: 182 TNIIVAVVDTGVDGTHPDLEG---QVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAA 238 NI VA++D VD HP +G V+ P A + +HGTHVA I Sbjct: 27 HNIRVAILDGPVDIAHPCFQGADLTVLPTLAPT------AARSDGFMSAHGTHVASIIFG 80 Query: 239 KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWG- 297 + + + G+AP + + + IF D + +A GI A + GA ++N S G Sbjct: 81 QPETS-VPGIAPQCRGLIVPIFSDDRR-----RITQLDLARGIERAVNAGAHIINISGGE 134 Query: 298 ---GWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTF 354 ++ A ++ V++V +AGNN D PA P V+ V A+D +G Sbjct: 135 LTDFGEADGWLENAVSLCRQNNVLLVAAAGNNGCD-CLHVPAALPAVLAVGAMDDHGHPL 193 Query: 355 RVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPH 414 + + S + + APG IL PG G + GTS A P Sbjct: 194 DFSNWGSTYEQQGILAPGEDILGAKPG------------------GGTERLSGTSFATPI 235 Query: 415 VTGVVAVLLQ----KFPNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLP 470 V+GV A+LL + P ++R+LL +A + + + +L+ + L Sbjct: 236 VSGVAALLLSEQVRRGETPDPQKVRQLLLQSALPCDDDAPEQARRCLAGRLNVSGAFTLL 295 Query: 471 TQGGVEE 477 G + E Sbjct: 296 KGGNMSE 302 >2GKO-A nrPDB Length = 309 Score = 205 bits (521), Expect = 6e-53, Method: Composition-based stats. Identities = 100/330 (30%), Positives = 138/330 (41%), Gaps = 53/330 (16%) Query: 161 NELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT 220 + WG++AI L + G I +AV+DTGV+ HPDL V Sbjct: 5 STPWGIKAIYNNSNLTSTSGGAGINIAVLDTGVNTNHPDLSNNVEQCKDFTVGTNFTD-N 63 Query: 221 DSSYGGSHGTHVAGTIAAK-KDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAA 279 + HGTHVAG+ A G G+ GVAP A + + D G+GY D +A Sbjct: 64 SCTDRQGHGTHVAGSALANGGTGSGVYGVAPEADLWAYKVLGDD----GSGYA--DDIAE 117 Query: 280 GIIWATDHGAK-----VMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTS-DSHHQ 333 I A D V+N S G G S + A DYA + GV+++ +AGN+ Sbjct: 118 AIRHAGDQATALNTKVVINMSLGSSGESSLITNAVDYAYDKGVLIIAAAGNSGPKPGSIG 177 Query: 334 YPAGYPGVIQVAALDY--YGGTFRVAGFSSRSD------------GVSVGAPGVTILSTV 379 YP + VAAL+ GT+RVA FSSR V + APG + ST Sbjct: 178 YPGALVNAVAVAALENTIQNGTYRVADFSSRGHKRTAGDYVIQKGDVEISAPGAAVYSTW 237 Query: 380 PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLE 439 G Y GTSMA+PH G+ A + + P A +R L+ Sbjct: 238 F------------------DGGYATISGTSMASPHAAGLAAKIWAQSPAASNVDVRGELQ 279 Query: 440 NTAF-------DFNGNGWDHDTGYGLVKLD 462 A + G+G D +G+G K+ Sbjct: 280 TRASVNDILSGNSAGSGDDIASGFGFAKVQ 309 >5YL7-A nrPDB Length = 347 Score = 198 bits (504), Expect = 5e-51, Method: Composition-based stats. Identities = 102/343 (29%), Positives = 150/343 (43%), Gaps = 53/343 (15%) Query: 148 LNSTARDYGEELSNELWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAG 207 N D + GL W+ A+G+ ++VAV+DTG H DL ++ G Sbjct: 3 PNDPRFDDQWHYYEQAGGLN----LPTAWDTATGSGVVVAVLDTGYR-PHADLNANILPG 57 Query: 208 YR----------------------PAFDEELPAGTDSSYGGSHGTHVAGTIAA-KKDGKG 244 Y A + HGTHVAGT+AA +G+G Sbjct: 58 YDMISNLSVANDGGGRDSDARDPGDAVAANECGTNGAQNSSWHGTHVAGTVAAVTNNGEG 117 Query: 245 IVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWA----------TDHGAKVMNH 294 + GVA AK++P+ + + +A GIIWA + A V+N Sbjct: 118 VAGVAYNAKVVPVRVLGKCGGL-------TSDIADGIIWASGGSVSGIPANSNPADVINM 170 Query: 295 SWGGWGYSY-TMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGT 353 S GG G T + A + A +G V+V++AGN+ +S + P GV+ VA++ GG Sbjct: 171 SLGGSGSCSSTTQNAINTARSNGTVVVIAAGNDNDNSANYNPGNCNGVVNVASVGRNGG- 229 Query: 354 FRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIG-YEGHNENVPATNGGTYDYYQGTSMAA 412 A +S+ + V APG + DS G +N + +Y Y QGTSMAA Sbjct: 230 --RAYYSNYGSNIDVAAPG---GAQSFANDSEGVLSTYNSGSSTPSSDSYGYSQGTSMAA 284 Query: 413 PHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGWDHDTG 455 PHV GV A++ Q P+A P +I +L++T F TG Sbjct: 285 PHVAGVAALIKQAKPDATPDEIESILKSTTRSFPATCTSCGTG 327 >4MZD-A nrPDB Length = 488 Score = 198 bits (503), Expect = 7e-51, Method: Composition-based stats. Identities = 89/376 (23%), Positives = 143/376 (38%), Gaps = 68/376 (18%) Query: 121 EPSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSNELWGLEAIGVTQQLWEEAS 180 +P +++ ++ N K + DY W ++ + + + Sbjct: 37 QPLKNQKVEAQPLLISNSSEKKASVYTNSHDFWDY-------QWDMKYVTNNGESYALYQ 89 Query: 181 GTN-IIVAVVDTGVDGTHPDLEGQV---------IAGYRPAFDEELPAGTDSSYGGSHGT 230 + I V ++D+G+ HPDL + G+ +E +D HGT Sbjct: 90 PSKKISVGIIDSGIMEEHPDLSNSLGNYFKNLVPKGGFDNEEPDETGNPSDIVDKMGHGT 149 Query: 231 HVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAK 290 VAG I A + I+GVAPG + +F G ++VA I A D G K Sbjct: 150 EVAGQITANGN---ILGVAPGITVNIYRVF-------GENLSKSEWVARAIRRAADDGNK 199 Query: 291 VMNHSWGGW---GYSY-----------TMKEAFDYAMEHGVVMVVSAGNNT--------- 327 V+N S G + SY K A +YA G ++V + GN++ Sbjct: 200 VINISAGQYLMISGSYDDGTNDYQEYLNYKSAINYATAKGSIVVAALGNDSLNIQDNQTM 259 Query: 328 ------------SDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTI 375 P+ + VI V +D YG ++ FS+ G T Sbjct: 260 INFLKRFRSIKVPGKVVDAPSVFEDVIAVGGIDGYG---NISDFSNIGADAIYAPAGTTA 316 Query: 376 LSTVPGED---SIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPW 432 G+D S GY + TN G Y Y G S A P V+G +A+++ K+ P Sbjct: 317 NFKKYGQDKFVSQGYYLKDWLFTTTNTGWYQYVYGNSFATPKVSGALALVVDKYGIKNPN 376 Query: 433 QIRKLLENTAFDFNGN 448 Q+++ L + + NGN Sbjct: 377 QLKRFLLMNSPEVNGN 392 >6F5G-A nrPDB Length = 703 Score = 197 bits (501), Expect = 1e-50, Method: Composition-based stats. Identities = 85/330 (25%), Positives = 127/330 (38%), Gaps = 44/330 (13%) Query: 154 DYGEELSNE-----LWGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQV 204 DY EE S+ W LE I + +E G+ + V ++DT + H ++EG+V Sbjct: 141 DYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRV 200 Query: 205 IAGYRPAFDEELPA--GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDD 262 + EE +S SHGTH+AG ++ + GVA GA + + + + Sbjct: 201 MVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVLN- 254 Query: 263 PALVGGNGYVGDDYVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVV 318 G G V + I + G V+ G GYS + A GVV Sbjct: 255 ---CQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAGVV 310 Query: 319 MVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFS-SRSDGVSVGAPGVTILS 377 +V +AGN D+ PA P VI V A + + + V + APG I+ Sbjct: 311 LVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIG 370 Query: 378 TVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKL 437 + + GTS AA HV G+ A++L P ++R+ Sbjct: 371 A----------------SSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQR 414 Query: 438 L-ENTAFDFNGNGW-DHDTGYGLVKLDAAL 465 L +A D W D L AAL Sbjct: 415 LIHFSAKDVINEAWFPEDQRVLTPNLVAAL 444 >3AFG-A nrPDB Length = 539 Score = 196 bits (498), Expect = 3e-50, Method: Composition-based stats. Identities = 85/287 (29%), Positives = 124/287 (43%), Gaps = 40/287 (13%) Query: 196 THPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK--KDGKGIVGVAPGAK 253 +HPDL+G+VI + P HGTHVA A G+APGAK Sbjct: 153 SHPDLQGKVIGWVDFVNGKTTPY-----DDNGHGTHVASIAAGTGAASNGKYKGMAPGAK 207 Query: 254 IMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDH----GAKVMNHSWGGWGYSY---TMK 306 ++ I + + G G + G+ WA + G KV+N S G S ++ Sbjct: 208 LVGIKVLN------GQGSGSISDIINGVDWAVQNKDKYGIKVINLSLGSSQSSDGTDSLS 261 Query: 307 EAFDYAMEHGVVMVVSAGNNTSDSHH-QYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDG 365 +A + A + G+V+VV+AGN+ + + PA VI V A+D Y + FSSR Sbjct: 262 QAVNNAWDAGLVVVVAAGNSGPNKYTVGSPAAASKVITVGAVDKYDV---ITDFSSRGPT 318 Query: 366 VS------VGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVV 419 V APG I++ S+G ++ Y GT+MA PHV G+ Sbjct: 319 ADNRLKPEVVAPGNWIIAARASGTSMGQPINDY---------YTAAPGTAMATPHVAGIA 369 Query: 420 AVLLQKFPNAKPWQIRKLLENTAFDFNGNGW-DHDTGYGLVKLDAAL 465 A+LLQ P+ P +++ L TA + D G G V A Sbjct: 370 ALLLQAHPSWTPDKVKTALIETADIVKPDEIADIAYGAGRVNAYKAA 416 >5VLH-A nrPDB Length = 460 Score = 196 bits (497), Expect = 4e-50, Method: Composition-based stats. Identities = 85/330 (25%), Positives = 127/330 (38%), Gaps = 44/330 (13%) Query: 154 DYGEELSNE-----LWGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQV 204 DY EE S+ W LE I + +E G+ + V ++DT + H ++EG+V Sbjct: 141 DYIEEDSSVFAQSIPWNLERITPPRYSADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRV 200 Query: 205 IAGYRPAFDEELPA--GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDD 262 + EE +S SHGTH+AG ++ + GVA GA + + + + Sbjct: 201 MVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVLN- 254 Query: 263 PALVGGNGYVGDDYVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVV 318 G G V + I + G V+ G GYS + A GVV Sbjct: 255 ---CQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAGVV 310 Query: 319 MVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFS-SRSDGVSVGAPGVTILS 377 +V +AGN D+ PA P VI V A + + + V + APG I+ Sbjct: 311 LVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIG 370 Query: 378 TVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKL 437 + + GTS AA HV G+ A++L P ++R+ Sbjct: 371 A----------------SSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQR 414 Query: 438 L-ENTAFDFNGNGW-DHDTGYGLVKLDAAL 465 L +A D W D L AAL Sbjct: 415 LIHFSAKDVINEAWFPEDQRVLTPNLVAAL 444 >4K8R-B nrPDB Length = 548 Score = 194 bits (493), Expect = 1e-49, Method: Composition-based stats. Identities = 80/318 (25%), Positives = 122/318 (38%), Gaps = 39/318 (12%) Query: 161 NELWGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEEL 216 + W LE I + +E G+ + V ++DT + H ++EG+V+ EE Sbjct: 1 SIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEED 60 Query: 217 PA--GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD 274 +S SHGTH+AG ++ + GVA GA + + + + G G V Sbjct: 61 GTRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVLN----CQGKGTVSG 111 Query: 275 DYVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDS 330 + I + G V+ G GYS + A GVV+V +AGN D+ Sbjct: 112 TLIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAGVVLVTAAGNFRDDA 170 Query: 331 HHQYPAGYPGVIQVAALDYYGGTFRVAGFS-SRSDGVSVGAPGVTILSTVPGEDSIGYEG 389 PA P VI V A + + + V + APG I+ Sbjct: 171 CLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGA----------- 219 Query: 390 HNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLL-ENTAFDFNGN 448 + + GTS AA HV G+ A++L P ++R+ L +A D Sbjct: 220 -----SSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINE 274 Query: 449 GW-DHDTGYGLVKLDAAL 465 W D L AAL Sbjct: 275 AWFPEDQRVLTPNLVAAL 292 >4ZOQ-I nrPDB Length = 343 Score = 193 bits (490), Expect = 3e-49, Method: Composition-based stats. Identities = 80/350 (22%), Positives = 136/350 (38%), Gaps = 69/350 (19%) Query: 164 WGLEAI-GVTQQLWEEASGTN-------------IIVAVVDTGVDGTHPDLEGQVIAGYR 209 WGL+ I + + LW A T+ + VA++D+G+D HPDL+ V Sbjct: 11 WGLDGILELKEYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPDLKASVNTNGG 70 Query: 210 PAFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGN 269 + + P D + HGT AG I +AP I P + D+ GG+ Sbjct: 71 WNYIDGKPVSGDPT---GHGTQTAGMINI---------IAPDVTITPYQVLDEK---GGD 115 Query: 270 GYVGDDYVAAGIIWATDHGAKVMNHSWGGWGY--------SYTMKEAFDYAMEHGVVMVV 321 Y + ++ A + G +V+N S G + + A +YA +H V++ Sbjct: 116 SY----NIMKAMVDAVNDGHEVINISTGSYTSLDREGKVLMKAYQRAANYAAKHQVLVFS 171 Query: 322 SAGNNT--------SDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGV 373 SAGN +++ P+ V+ V + + ++ +S++ + APG Sbjct: 172 SAGNKGVNLDEMRKTENKVHLPSALKHVVSVGS---NMKSNNISPYSNQGREIEFTAPGG 228 Query: 374 TILSTV------------PGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAV 421 + T G + + Y GTS+AAP V G A+ Sbjct: 229 YLGETYDQDGMVRVTDLVLTTYPKGKDNTALDQMLNIPKGYSLSYGTSLAAPQVAGTAAL 288 Query: 422 LLQKFPN-----AKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQ 466 ++ ++ Q+ +L +A D G D GYG V+ AL+ Sbjct: 289 VISEYRERHHRKPSAKQVHHILRKSALDLGKPGKDVIYGYGEVRAYQALK 338 >5MIM-A nrPDB Length = 482 Score = 190 bits (483), Expect = 2e-48, Method: Composition-based stats. Identities = 76/349 (21%), Positives = 127/349 (36%), Gaps = 54/349 (15%) Query: 150 STARDYGEELSNELWGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQV 204 ++ + + W L + V + +G I+V+++D G++ HPDL G Sbjct: 1 DVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNY 60 Query: 205 IAGYRPAFDEELPAGTDS---SYGGSHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIF 260 G +++ P HGT AG +AA +G VGVA A+I + + Sbjct: 61 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 120 Query: 261 DDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGG-------WGYSYTMKEAFDYAM 313 D G V D A + +H + + SWG G + +EAF + Sbjct: 121 D--------GEVTDAVEARSLGLNPNH-IHIYSASWGPEDDGKTVDGPARLAEEAFFRGV 171 Query: 314 EH-----GVVMVVSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSV 368 G + V ++GN + GY I ++ V +S Sbjct: 172 SQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYS-------- 223 Query: 369 GAPGVTILSTVPGEDSIGYEGHNENVPAT-NGGTYDYYQGTSMAAPHVTGVVAVLLQKFP 427 ST+ S G + + V + + GTS +AP G++A+ L+ Sbjct: 224 ----EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 279 Query: 428 NAKPWQIRKLLENTA--FDFNGNGW---------DHDTGYGLVKLDAAL 465 N ++ L+ T+ N N W H GYGL+ A + Sbjct: 280 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMV 328 >2W2P-A nrPDB Length = 312 Score = 190 bits (482), Expect = 2e-48, Method: Composition-based stats. Identities = 80/318 (25%), Positives = 122/318 (38%), Gaps = 39/318 (12%) Query: 161 NELWGLEAIGVTQQLWEEAS----GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEEL 216 + W LE I + +E G+ + V ++DT + H ++EG+V+ EE Sbjct: 1 SIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEED 60 Query: 217 PA--GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD 274 +S SHGTH+AG ++ + GVA GA + + + + G G V Sbjct: 61 GTRFHRQASKCDSHGTHLAGVVSGRD-----AGVAKGASMRSLRVLN----CQGKGTVSG 111 Query: 275 DYVAAGIIWATDH----GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDS 330 + I + G V+ G GYS + A GVV+V +AGN D+ Sbjct: 112 TLIGLEFIRKSQLVQPVGPLVVLLPLAG-GYSRVLNAACQRLARAGVVLVTAAGNFRDDA 170 Query: 331 HHQYPAGYPGVIQVAALDYYGGTFRVAGFS-SRSDGVSVGAPGVTILSTVPGEDSIGYEG 389 PA P VI V A + + + V + APG I+ Sbjct: 171 CLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGA----------- 219 Query: 390 HNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLL-ENTAFDFNGN 448 + + GTS AA HV G+ A++L P ++R+ L +A D Sbjct: 220 -----SSACSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINE 274 Query: 449 GW-DHDTGYGLVKLDAAL 465 W D L AAL Sbjct: 275 AWFPEDQRVLTPNLVAAL 292 >4KG7-A nrPDB Length = 381 Score = 189 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 87/339 (25%), Positives = 129/339 (38%), Gaps = 58/339 (17%) Query: 175 LWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAG 234 W+ + G VAV+DTGV P L G + + + + HGT VAG Sbjct: 58 AWQHSRGAGQTVAVIDTGVQ-PGPRLPNVEAGG------DYIESTDGLTDCDGHGTSVAG 110 Query: 235 TIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGD--------DYVAAGIIWATD 286 IA + G GVAP A+++ I G + + +A ++ A D Sbjct: 111 LIAGQPGPDGFSGVAPEARLISIRQNSPRFAPRTPGADSEATRAASDAETLARAVVRAAD 170 Query: 287 HGAKVMNHSWGGWGYS------YTMKEAFDYAM-EHGVVMVVSAGNN-------TSDSHH 332 GA+V+N S + + A YA E V+V +AGNN + + Sbjct: 171 MGARVINISLVTCLPADRTIDQSVLGAALRYAALEKDAVIVAAAGNNRGGVSTGAACESN 230 Query: 333 QYPAGYPG--------------------VIQVAALDYYGGTFRVAGFSSRSDGVSVGAPG 372 P+G PG V+ V A+D G + F+ V + APG Sbjct: 231 PLPSGTPGDPRNWNGVTSVSIPSWWQPYVLSVGAVDSTGQP---SSFTMAGPWVGIAAPG 287 Query: 373 VTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPW 432 I+S S +G N + GTS AA +V+GV A++ KFP+ Sbjct: 288 ENIVSV-----SNAPDGGLSNALPSERDRLVPLTGTSYAAAYVSGVAALVRSKFPDLTAR 342 Query: 433 QIRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLPT 471 Q+ L TA + G G+V AAL + Sbjct: 343 QVVHRLTTTAQG-AARSPSNLIGAGMVDPVAALTWDVAD 380 >2ID4-A nrPDB Length = 503 Score = 189 bits (479), Expect = 5e-48, Method: Composition-based stats. Identities = 84/371 (22%), Positives = 143/371 (38%), Gaps = 57/371 (15%) Query: 156 GEELSNELWGL-------EAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGY 208 + L W L I V + +G ++ A+VD G+D + DL+ A Sbjct: 21 NDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEG 80 Query: 209 RPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK-DGKGIVGVAPGAKIMPIVIFDDPALVG 267 F++ HGT AG IAAKK + VGV AKI I I Sbjct: 81 SWDFNDNTNLPKPRLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRIL------- 133 Query: 268 GNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNT 327 +G + + AA +I+ D + + SWG ++ D ++ +V V+ G ++ Sbjct: 134 -SGDITTEDEAASLIYGLDVN-DIYSCSWGPADDGRHLQGPSD-LVKKALVKGVTEGRDS 190 Query: 328 SDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGA-----------PGVTIL 376 + + + +G G G G+++ +++GA G + + Sbjct: 191 KGAIYVFASGNGGT--------RGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAV 242 Query: 377 STVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIR- 435 V G H+ ++ NG + + GTS AAP GV +LL+ PN ++ Sbjct: 243 MAVTYSSGSGEYIHSSDI---NGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQY 299 Query: 436 -KLLENTAFDFNGNGWDHDTG--------YGLVKLDAALQGPLPTQGGVEEFQVVVTDAK 486 +L + N +G D+ YG K+DA + +A+ Sbjct: 300 LSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWEN-------VNAQ 352 Query: 487 GNFGVPTVFVS 497 F +PT++VS Sbjct: 353 TWFYLPTLYVS 363 >5FAX-A nrPDB Length = 433 Score = 187 bits (475), Expect = 1e-47, Method: Composition-based stats. Identities = 89/317 (28%), Positives = 124/317 (39%), Gaps = 52/317 (16%) Query: 181 GTNIIVAVVDTGVD------GTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAG 234 G IVAV DTG+D H G++ A Y L +++ HGTHVAG Sbjct: 21 GQGQIVAVADTGLDTGRNDSSMHEAFRGKITALYA------LGRTNNANDPNGHGTHVAG 74 Query: 235 TIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNH 294 ++ K G+AP A ++ I D +GG + A GA++ + Sbjct: 75 SVLGNATNK---GMAPQANLVFQSIMDSGGGLGGL----PANLQTLFSQAYSAGARIHTN 127 Query: 295 SWGGW---GYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH-QYPAGYPGVIQVAALDYY 350 SWG Y+ + DY ++ + ++ +AGN S P I V A + Sbjct: 128 SWGAPVNGAYTTDSRNVDDYVRKNDMTILFAAGNEGPGSGTISAPGTAKNAITVGATENL 187 Query: 351 GGTF--------RVAGFSSRSDGV------SVGAPGVTILSTVP--GEDSIGYEGHNENV 394 +F VA FSSR V APG ILS DS + H+ Sbjct: 188 RPSFGSYADNINHVAQFSSRGPTRDGRIKPDVMAPGTYILSARSSLAPDSSFWANHDSK- 246 Query: 395 PATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPN-----AKPWQIRKLLENTAFDFNGNG 449 Y Y GTSMA P V G VA L + F KP ++ L A D Sbjct: 247 -------YAYMGGTSMATPIVAGNVAQLREHFVKNRGVTPKPSLLKAALIAGAADVGLGF 299 Query: 450 WDHDTGYGLVKLDAALQ 466 + + G+G V LD +L Sbjct: 300 PNGNQGWGRVTLDKSLN 316 >3F7O-A nrPDB Length = 284 Score = 186 bits (471), Expect = 4e-47, Method: Composition-based stats. Identities = 80/282 (28%), Positives = 120/282 (42%), Gaps = 42/282 (14%) Query: 162 ELWGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEEL 216 WGL I G T ++ + G+ V+DTGV+ +HP+ EG+ Sbjct: 8 APWGLGRISHRSKGSTTYEYDTSGGSGTCAYVIDTGVEASHPEFEGRASQIKSFI----- 62 Query: 217 PAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDY 276 ++ G HGTH AGTI +K GVA KI + + D+ +G + Sbjct: 63 --SGQNTDGNGHGTHCAGTIGSK-----TYGVAKKTKIYGVKVLDNSGSGSYSGIISGMD 115 Query: 277 VA-AGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYP 335 A + V N S GG G + ++ + + GV + V+AGN+ +++ + P Sbjct: 116 FAVQDSKSRSCPKGVVANMSLGG-GKAQSVNDGAAAMIRAGVFLAVAAGNDNANAANYSP 174 Query: 336 AGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVP 395 A P V V A + + FS+ + V + APG ILST G Sbjct: 175 ASEPTVCTVGATT---SSDARSSFSNYGNLVDIFAPGSNILSTWIG-------------- 217 Query: 396 ATNGGTYDYYQGTSMAAPHVTGVVAVL--LQKFPNAKPWQIR 435 GT + GTSMA PH+ G+ A L L+ FP A+ R Sbjct: 218 ----GTTNTISGTSMATPHIVGLGAYLAGLEGFPGAQALCKR 255 >1WMD-A nrPDB Length = 434 Score = 184 bits (467), Expect = 1e-46, Method: Composition-based stats. Identities = 87/317 (27%), Positives = 124/317 (39%), Gaps = 51/317 (16%) Query: 181 GTNIIVAVVDTGVD------GTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAG 234 G IVAV DTG+D H G++ A Y L +++ HGTHVAG Sbjct: 21 GQGQIVAVADTGLDTGRNDSSMHEAFRGKITALYA------LGRTNNANDTNGHGTHVAG 74 Query: 235 TIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNH 294 ++ +G G+AP A ++ I D +G + A GA++ + Sbjct: 75 SVLG--NGSTNKGMAPQANLVFQSIMDSGGGLG----GLPSNLQTLFSQAYSAGARIHTN 128 Query: 295 SWGGW---GYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHH-QYPAGYPGVIQVAALDYY 350 SWG Y+ + DY ++ + ++ +AGN + P I V A + Sbjct: 129 SWGAAVNGAYTTDSRNVDDYVRKNDMTILFAAGNEGPNGGTISAPGTAKNAITVGATENL 188 Query: 351 GGTF--------RVAGFSSRSD------GVSVGAPGVTILSTVP--GEDSIGYEGHNENV 394 +F VA FSSR V APG ILS DS + H+ Sbjct: 189 RPSFGSYADNINHVAQFSSRGPTKDGRIKPDVMAPGTFILSARSSLAPDSSFWANHDSK- 247 Query: 395 PATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPN-----AKPWQIRKLLENTAFDFNGNG 449 Y Y GTSMA P V G VA L + F KP ++ L A D Sbjct: 248 -------YAYMGGTSMATPIVAGNVAQLREHFVKNRGITPKPSLLKAALIAGAADIGLGY 300 Query: 450 WDHDTGYGLVKLDAALQ 466 + + G+G V LD +L Sbjct: 301 PNGNQGWGRVTLDKSLN 317 >3VV3-A nrPDB Length = 334 Score = 175 bits (443), Expect = 7e-44, Method: Composition-based stats. Identities = 83/306 (27%), Positives = 127/306 (41%), Gaps = 54/306 (17%) Query: 156 GEELSNELWGLEAIGVT----------QQLWEEASGT-NIIVAVVDTGVDGTHPDLEGQV 204 + ++LWGL G T + W ++G+ +++V V+DTGVD +HPDL Sbjct: 5 NDPRFDDLWGLNNEGQTGGTADADIDAPEAWSISTGSRDVVVGVIDTGVDYSHPDLAANA 64 Query: 205 -IAGYRPAFDEELPAGT----------------DSSYGGSHGTHVAGTIAAKKDGKGIVG 247 + A D G D HGTHV+GTI A + V Sbjct: 65 WVNSGEIAGDGIDNDGNGYIDDVHGINAITDVGDPMDDEGHGTHVSGTIGASGNNGVGVV 124 Query: 248 VAP-GAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMK 306 I+ +G + G+ A +V+N+SWGG G+S + Sbjct: 125 GVNHDVSIVGCKFLAADGTGSTSGAIKCIDYMVGLKNAG-VNLRVLNNSWGGGGFSQALA 183 Query: 307 EAFDYAMEHGVVMVVSAGNNT--SDSHHQYPAGY--PGVIQVAALDYYGGTFRVAGFSSR 362 +A + + ++ V +AGN+ +D + YP+ Y V+ +A+ D + + Sbjct: 184 DAITASEQADILFVAAAGNDAVDNDQNPHYPSNYENDNVLSIASTDSRDNMSSFSQWG-- 241 Query: 363 SDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVL 422 V +GAPG ILSTVPG +Y Y GTSMA PHV G A++ Sbjct: 242 LTSVDMGAPGSGILSTVPGN------------------SYATYSGTSMATPHVAGAAALV 283 Query: 423 LQKFPN 428 L P+ Sbjct: 284 LSVNPD 289 >1V6C-A nrPDB Length = 441 Score = 173 bits (439), Expect = 2e-43, Method: Composition-based stats. Identities = 79/264 (29%), Positives = 117/264 (44%), Gaps = 20/264 (7%) Query: 163 LWGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDS 222 WG +G T + ++ N + ++D+G D +H DL + G + + Sbjct: 5 PWGQTFVGAT--VLSDSQAGNRTICIIDSGYDRSHNDLNANNVTGTNNSGTGNWYQPGN- 61 Query: 223 SYGGSHGTHVAGTIAAKKDGKGIVGVAPG--AKIMPIVIFDDPALVGGNGYVGDDYVAAG 280 +HGTHVAGTIAA + +G+VGV P A I + +F++ G GY VAA Sbjct: 62 --NNAHGTHVAGTIAAIANNEGVVGVMPNQNANIHIVKVFNE----AGWGY-SSSLVAAI 114 Query: 281 IIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQYPAGYPG 340 GA V+ S GG G + T + A + +GV+++ +AGN DS + YPA Y Sbjct: 115 DTCVNSGGANVVTMSLGGSGSTTTERNALNTHYNNGVLLIAAAGNAG-DSSYSYPASYDS 173 Query: 341 VIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGG 400 V+ VAA+D A FS +D V + PG ILSTV + + + G Sbjct: 174 VMSVAAVD---SNLDHAAFSQYTDQVEISGPGEAILSTVTVGEGRLADITIGGQSYFSNG 230 Query: 401 TYD----YYQGTSMAAPHVTGVVA 420 GTS A + Sbjct: 231 VVPHNRLTPSGTSYAPAPINASAT 254 Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Query: 367 SVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKF 426 + P V++ G G + V Y+YY GTSMA PHV+GV ++ Sbjct: 328 DITVPSVSVDRA-TGLALKAKLGQSTTVSNQGNQDYEYYNGTSMATPHVSGVATLVWSYH 386 Query: 427 PNAKPWQIRKLLENTAFDFNGNGWDHDTGYGLVKLDAA 464 P Q+R L TA D + G D+ TGYG++ AA Sbjct: 387 PECSASQVRAALNATADDLSVAGRDNQTGYGMINAVAA 424 >5Z6O-A nrPDB Length = 282 Score = 170 bits (431), Expect = 2e-42, Method: Composition-based stats. Identities = 86/296 (29%), Positives = 123/296 (41%), Gaps = 52/296 (17%) Query: 164 WGLEAI-----GVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPA 218 WGL I G T +++ +G I++ VDTG+D H D G+ G A +++ Sbjct: 11 WGLSRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADNDDT-- 68 Query: 219 GTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVA 278 G HGTH A T A K GVA A ++ + + G +G + V Sbjct: 69 -----DGNGHGTHTASTAAGSK-----FGVAKKASVVAVKVL------GADGSGTNSQVI 112 Query: 279 AGIIWATDH-------GAKVMNHSWGGWGYSYTMKEAFDYAMEHGVVMVVSAGNNTSDSH 331 AG+ WA G VMN S GG YS M +A + GV + V+AGN D+ Sbjct: 113 AGMDWAVKDSKSRGATGKSVMNMSLGG-AYSRAMNDAAANVVRSGVFLSVAAGNEAQDAS 171 Query: 332 HQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHN 391 + PA P V +AA G+ A F++ V + APG I + PG Sbjct: 172 NSSPASAPNVCTIAASTNSDGS---ASFTNFGSVVDLYAPGKDITAAYPG---------- 218 Query: 392 ENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNG 447 G GTSMAAPHV G A L+ +++++ +G Sbjct: 219 --------GGSKTLSGTSMAAPHVAGAAAYLMALEGTTTSSACARIVQDAITKISG 266 >4H6X-A nrPDB Length = 357 Score = 164 bits (416), Expect = 9e-41, Method: Composition-based stats. Identities = 58/275 (21%), Positives = 104/275 (37%), Gaps = 31/275 (11%) Query: 211 AFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNG 270 A + +P D H HV TI ++ + G+AP +++ + D + Sbjct: 92 ALEAVIPDTKDRIVLNDHACHVTSTIVGQEHSP-VFGIAPNCRVINMPQ-DAVIRGNYDD 149 Query: 271 YVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMK----EAFDYAMEHGVVMVVSAGNN 326 + +A I A + GA +++ ++ + + +A ++ V++V GNN Sbjct: 150 VMSPLNLARAIDLALELGANIIHCAFCRPTQTSEGEEILVQAIKKCQDNNVLIVSPTGNN 209 Query: 327 TSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIG 386 +++S PA PG + V A G + + + + APG IL P + Sbjct: 210 SNESW-CLPAVLPGTLAVGAAKVDGTPCHFSNWGGNNTKEGILAPGEEILGAQPCTEEP- 267 Query: 387 YEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQ----KFPNAKPWQIRKLLENTA 442 GTSMAAP +TG+ A+L+ + +R L TA Sbjct: 268 ----------------VRLTGTSMAAPVMTGISALLMSLQVQQGKPVDAEAVRTALLKTA 311 Query: 443 FDFNGNGWDHDTGY--GLVKLDAALQGPLPTQGGV 475 + + G V + A++ L Q V Sbjct: 312 IPCDPEVVEEPERCLRGFVNIPGAMK-VLFGQPSV 345 >3HJR-A nrPDB Length = 600 Score = 162 bits (410), Expect = 4e-40, Method: Composition-based stats. Identities = 77/382 (20%), Positives = 131/382 (34%), Gaps = 93/382 (24%) Query: 175 LWEEASG---TNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGTDSSYGGSHGTH 231 W +G + VAVVD G+ HPDL V G + + +HGT Sbjct: 60 WWAHRTGVLGQGVNVAVVDDGLAIAHPDLADNVRPGSKNVVTGSDDPTP-TDPDTAHGTS 118 Query: 232 VAGTIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKV 291 V+G IAA + G G+AP A++ + DD + + D++ A +V Sbjct: 119 VSGIIAAVDNAIGTKGIAPRAQLQGFNLLDD-----NSQQLQKDWLYALGDSNASRDNRV 173 Query: 292 MNHSWGGWGYSYTMKEAFDYAM-----------EHGVVMVVSAGN------------NTS 328 N S+G + D + G + +AGN N + Sbjct: 174 FNQSYGMSVVDPRSANSLDQSQLDRLFEQQTLKAQGAAYIKAAGNGFNKIAAGGYVLNRT 233 Query: 329 DSHHQYPAGYPGV---------IQVAALDYYGGTFRVAGFSSRSDGVSVGAPG------- 372 + + P + + V+AL+ G + +SS + + A G Sbjct: 234 GNGPKLPFENSNLDPSNSNFWNLVVSALNADGV---RSSYSSVGSNIFLSATGGEYGTDT 290 Query: 373 -VTILSTVPGEDSIGYEGHNENVPATNGGTYDY---------YQGTSMAAPHVTGVVAVL 422 + + +PG D +GY ++ G GTS A P +G +A+L Sbjct: 291 PAMVTTDLPGCD-MGYNRTDDPSTNRLHGNSQLDASCDYNGVMNGTSSATPSTSGAMALL 349 Query: 423 LQKFPNAKPWQIRKLLENTAFDF----------------------NGNGWDHD------- 453 + +P+ +R LL +A GW+ + Sbjct: 350 MSAYPDLSVRDLRDLLARSATRVDAKHQPVMVSYTSSTGKVRDVKGLEGWERNAAGMWFS 409 Query: 454 --TGYGLVKLDAALQGPLPTQG 473 G+GL+ ++ AL+ Q Sbjct: 410 PTYGFGLIDVNKALELAANHQP 431 >1XF1-A nrPDB Length = 926 Score = 114 bits (285), Expect = 1e-25, Method: Composition-based stats. Identities = 61/221 (27%), Positives = 92/221 (41%), Gaps = 42/221 (19%) Query: 177 EEASGTNIIVAVVDTGVDGTHP--DLEGQVIAGYRPAFD-----------------EELP 217 + G +VAV+D G D H L + A Y+ D +++ Sbjct: 12 KAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVA 71 Query: 218 AGTDSSYGG------SHGTHVAGTIAAK-----KDGKGIVGVAPGAKIMPIVIFDDPALV 266 D S G HGTHV+G ++ K+ + G P A+++ + + +V Sbjct: 72 YYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRV----EIV 127 Query: 267 GGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYT-----MKEAFDYAMEHGVVMVV 321 G +Y A I A + GAKV+N S+G +Y K+AFDYA GV +V Sbjct: 128 NGLADYARNY-AQAIRDAINLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVT 186 Query: 322 SAGNNTS-DSHHQYP-AGYPGVIQVAALDYYGGTFRVAGFS 360 SAGN++S + P A +P V T VA +S Sbjct: 187 SAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYS 227 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 52/149 (34%), Gaps = 34/149 (22%) Query: 337 GYPGVIQVAALDYYGGTFRVAGFSSRSDGV---SVGAPGVTILSTVPGEDSIGYEGHNEN 393 + +V R + + +DG + APG ILS+V Sbjct: 350 TFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNK---------- 399 Query: 394 VPATNGGTYDYYQGTSMAAPHVTGVVAVLLQ----KFPNAKPWQ----IRKLLENTAF-- 443 Y GTSM+AP V G++ +L + ++P+ P + +K+L ++A Sbjct: 400 --------YAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATAL 451 Query: 444 ---DFNGNGWDHDTGYGLVKLDAALQGPL 469 D G G V A + Sbjct: 452 YDEDEKAYFSPRQQGAGAVDAKKASAATM 480 >4BWG-A nrPDB Length = 347 Score = 90.5 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 61/281 (21%), Positives = 93/281 (33%), Gaps = 66/281 (23%) Query: 200 LEGQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKKDGKGIVGVAPGAKIMPIVI 259 L A + D S HGT +A IA++ GI GV P A I + Sbjct: 61 LSDSEFAKFSFTQDGSPFPVKKSEALYIHGTAMASLIASR---YGIYGVYPHALISSRRV 117 Query: 260 FDDPALVGGNGYVGDDYVAAGIIWATDH------GAKVMNHSWGGWGYSYTM---KEAFD 310 D V D ++ I + K++N S G G + + Sbjct: 118 IPDG--------VQDSWI-RAIESIMSNVFLAPGEEKIINISGGQKGVASASVWTELLSR 168 Query: 311 YAMEHGVVMVVSAGNNTSD------SHHQYPAGY----------PGVIQVAALDYY---- 350 + ++V + GN+ +D +PA Y VI+VAAL Y Sbjct: 169 MGRNNDRLIVAAVGNDGADIRKLSAQQRIWPAAYHPVSSVNKKQDPVIRVAALAQYRKGE 228 Query: 351 -----GGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYY 405 GG + F + V + APG I P Sbjct: 229 TPVLHGGGITGSRFGNN--WVDIAAPGQNITFLRP------------------DAKTGTG 268 Query: 406 QGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFN 446 GTS A V+GV+A + P A ++++ L +A + Sbjct: 269 SGTSEATAIVSGVLAAMTSCNPRATATELKRTLLESADKYP 309 >4I0W-B nrPDB Length = 477 Score = 85.9 bits (211), Expect = 6e-17, Method: Composition-based stats. Identities = 39/194 (20%), Positives = 66/194 (34%), Gaps = 28/194 (14%) Query: 167 EAIGVTQQLWEEA--SGTNIIVAVVDTGVDGTHPDLE---GQVIAGYRPAFDEELPAGTD 221 +W +G I+V +DTG+D TH + G Y + + + Sbjct: 5 NRASCIPSVWNNYNLTGEGILVGFLDTGIDYTHNAFKDAEGNTRIEYIYDLENGVVYDKN 64 Query: 222 S----------------SYGGSHGTHVAGTI-AAKKDGKGIVGVAPGAKIMPIVIFDDPA 264 HGTHVAG A GVA + I + I + + Sbjct: 65 KINEALKSEDPFSIVPEIDLSGHGTHVAGIACAGGNINFDNYGVAYKSSIAMVKITGENS 124 Query: 265 LVGGNGYVGDDYVAAGIIWATD-HGAKVMNHSW----GGWGYSYTMKEAFDYAME-HGVV 318 L + + + + + V+N S G S +++ + V Sbjct: 125 LRAALSTQLMRGLKFLMDKSNEINKPLVVNISLSTNDGSHNGSSLLEKYIQTFTQLQKAV 184 Query: 319 MVVSAGNNTSDSHH 332 +VV+AGN + +HH Sbjct: 185 IVVAAGNEGNSAHH 198 Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 41/148 (27%), Positives = 56/148 (37%), Gaps = 35/148 (23%) Query: 330 SHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGV-------SVGAPGVTILSTVPGE 382 + PA GVI V + ++ ++ FS R + APG ILSTV Sbjct: 332 NTLGIPATVEGVISVGSYNFL--NNNLSAFSGRGVVRPEWLIKPDLVAPGENILSTV--- 386 Query: 383 DSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQ------KFPNAKPWQIRK 436 +D GTSMAAP V+G+ A+L + P +I+ Sbjct: 387 ---------------EEQGFDTKSGTSMAAPQVSGICALLFEWGIIRNNDPFLYGERIKY 431 Query: 437 LLENTAFD--FNGNGWDHDTGYGLVKLD 462 L A F + D GYG V LD Sbjct: 432 YLIKGAKRTIFGEAYPNPDLGYGFVCLD 459 >4YN3-A nrPDB Length = 621 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 30/120 (25%), Positives = 43/120 (35%), Gaps = 19/120 (15%) Query: 358 GFSSRSDGV--------SVGAPGVTILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTS 409 FSSR + PGV IL+ P +G ++ GTS Sbjct: 364 SFSSRGPNRATKDVIKPDISGPGVEILAAWPSVAPVG--------GIRRNTLFNIISGTS 415 Query: 410 MAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGNGW---DHDTGYGLVKLDAALQ 466 M+ PH+TG+ + P P I+ L TA N + G G V A++ Sbjct: 416 MSCPHITGIATYVKTYNPTWSPAAIKSALMTTASPMNARFNPQAEFAYGSGHVNPLKAVR 475 Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 42/227 (18%), Positives = 71/227 (31%), Gaps = 47/227 (20%) Query: 182 TNIIVAVVDTGVDGTHPDLEGQVIA--------------------------GYRPAFDEE 215 +NI+V V+DTG+ P + + + Y Sbjct: 22 SNIVVGVLDTGIWPESPSFDDEGFSPPPPKWKGTCETSNNFRCNRKIIGARSYHIGRPIS 81 Query: 216 LPAGTDSSYGGSHGTHVAGTIAA----KKDGKGI-VGVA----PGAKIMPIVIFDDPALV 266 HGTH A T A + + G+ +G A P A+I + + Sbjct: 82 PGDVNGPRDTNGHGTHTASTAAGGLVSQANLYGLGLGTARGGVPLARIAAYKVCWNDGC- 140 Query: 267 GGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYSYTMKEAFD----YAMEHGVVMVVS 322 D + A A G +++ S GG + +A +A+E G++ S Sbjct: 141 ------SDTDILAAYDDAIADGVDIISLSVGGANPRHYFVDAIAIGSFHAVERGILTSNS 194 Query: 323 AGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVG 369 AGN + + P ++ VAA + V Sbjct: 195 AGNGGPNFFTTA-SLSPWLLSVAASTMDRKFVTQVQIGNGQSFQGVS 240 >3I6S-A nrPDB Length = 649 Score = 70.5 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 63/201 (31%), Gaps = 39/201 (19%) Query: 168 AIGVTQQLWEEAS-GTNIIVAVVDTGV--------DGTHPDLEGQ--------------- 203 + + LW + G ++IVAV+D+G+ D P++ + Sbjct: 9 KLNPSSGLWPASGLGQDVIVAVLDSGIWPESASFQDDGMPEIPKRWKGICKPGTQFNASM 68 Query: 204 ----------VIAGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAK-KDGKGIVGVAPG- 251 G + HGTH A A G G APG Sbjct: 69 CNRKLIGANYFNKGILANDPTVNITMNSARDTDGHGTHCASITAGNFAKGVSHFGYAPGT 128 Query: 252 AKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGG---WGYSYTMKEA 308 A+ + N + A + A G +++ S+G Y + A Sbjct: 129 ARGVAPRARLAVYKFSFNEGTFTSDLIAAMDQAVADGVDMISISYGYRFIPLYEDAISIA 188 Query: 309 FDYAMEHGVVMVVSAGNNTSD 329 AM GV++ SAGN Sbjct: 189 SFGAMMKGVLVSASAGNRGPG 209 Score = 52.0 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 40/137 (29%), Positives = 50/137 (36%), Gaps = 20/137 (14%) Query: 341 VIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNENVPATNGG 400 VAA G + G S + APGV IL+ P G N + Sbjct: 366 APVVAASSARGPSRSYLGIS----KPDILAPGVLILAAYPPNVFATSIGTNILLSTD--- 418 Query: 401 TYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTAFDFNGN-----GWDH--- 452 Y GTSMAAPH G+ A+L P P IR + TA + D+ Sbjct: 419 -YILESGTSMAAPHAAGIAAMLKAAHPEWSPSAIRSAMMTTADPLDNTRKPIKDSDNNKA 477 Query: 453 ----DTGYGLVKLDAAL 465 D G G V + AL Sbjct: 478 ATPLDMGAGHVDPNRAL 494 >1T1E-A nrPDB Length = 552 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 69/361 (19%), Positives = 100/361 (27%), Gaps = 83/361 (22%) Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPA-------FDEELPAGTDSSYGGSHGTHVA 233 G +A+++ G L + A D T G Sbjct: 211 GQGQCIAIIELGGGYDETSLAQYFASLGVSAPQVVSVSVDGATNQPTGDPNGPD------ 264 Query: 234 GTIAAKKDGKGIVGV-APGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVM 292 G + + + G APGAKI N G + H ++ Sbjct: 265 GEV---ELDIEVAGALAPGAKIAVY--------FAPNTDAGFLNAITTAVHDPTHKPSIV 313 Query: 293 NHSWGGWGYS------YTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ-------YPAGYP 339 + SWGG S M AF A GV ++ +AG++ S Q +PA P Sbjct: 314 SISWGGPEDSWAPASIAAMNRAFLDAAALGVTVLAAAGDSGSTDGEQDGLYHVDFPAASP 373 Query: 340 GVIQVAALDYYGGTFRV-------------------------AGFSSRSDGVSVGAPGVT 374 V+ R+ + R++ PG Sbjct: 374 YVLACGGTRLVASAGRIERETVWNDGPDGGSTGGGVSRIFPLPSWQERANVPPSANPGAG 433 Query: 375 ILSTVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQK--------F 426 VP D G G GT+ AP +VA + QK Sbjct: 434 SGRGVP--DVAGNADPATGYEVVIDGETTVIGGTAAVAPLFAALVARINQKLGKPVGYLN 491 Query: 427 PNA--KPWQIRKLLENTAFDF--------NGNGWDHDTGYGLVKLDAALQGPLPTQGGVE 476 P P ++ + D G GWD TG G LQ LP+ + Sbjct: 492 PTLYQLPPEVFHDITEGNNDIANRARIYQAGPGWDPCTGLGSPIGIRLLQALLPSASQAQ 551 Query: 477 E 477 Sbjct: 552 P 552 >1GA6-A nrPDB Length = 372 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 61/297 (20%), Positives = 88/297 (29%), Gaps = 62/297 (20%) Query: 180 SGTNIIVAVVD-TGVDGTHPDLE----GQVIAGYRPAFDEELPAGTDSSYGGSHGTHVAG 234 + N V ++ GV T DL+ +A + + D S G Sbjct: 24 TAANTTVGIITIGGVSQTLQDLQQFTSANGLASVNTQTIQTGSSNGDYSDDQQ------G 77 Query: 235 TIAAKKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHG-AKVMN 293 D + IVG A GA + D + G G + A AKV+N Sbjct: 78 QGEWDLDSQSIVGSAGGAVQQLLFYMADQSASGNTG------LTQAFNQAVSDNVAKVIN 131 Query: 294 HSWG-------GWGYSYTMKEAFDYAMEHGVVMVVSAGN------------NTSDSHHQY 334 S G G F A G VS+G+ + S + Sbjct: 132 VSLGWCEADANADGTLQAEDRIFATAAAQGQTFSVSSGDEGVYECNNRGYPDGSTYSVSW 191 Query: 335 PAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVS-------VGAPG------------VTI 375 PA P VI V Y + +S+ + + A G ++ Sbjct: 192 PASSPNVIAVGGTTLYTTSA--GAYSNETVWNEGLDSNGKLWATGGGYSVYESKPSWQSV 249 Query: 376 LSTVPG----EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPN 428 +S PG D N G GTS+A+P G+ A L N Sbjct: 250 VSGTPGRRLLPDISFDAAQGTGALIYNYGQLQQIGGTSLASPIFVGLWARLQSANSN 306 >1SN7-A nrPDB Length = 364 Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 68/359 (18%), Positives = 99/359 (27%), Gaps = 79/359 (22%) Query: 181 GTNIIVAVVDTGVDGTHPDLEGQVIAGYRPA-----FDEELPAGTDSSYGGSHGTHVAGT 235 G +A+++ G L + PA + + + +G Sbjct: 23 GQGQCIAIIELGGGYDEASLAQYFASLGVPAPQVVSVSVDGASNQPTGDP-------SGP 75 Query: 236 IAAKKDGKGIVGV-APGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNH 294 + + G APGAK N G I V++ Sbjct: 76 DGEVELDIEVAGALAPGAKFAVY--------FAPNTDAGFLDAITTAIHDPTLKPSVVSI 127 Query: 295 SWGGWGYS------YTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ-------YPAGYPGV 341 SWGG S M AF A GV ++ +AG++ S Q +PA P V Sbjct: 128 SWGGPEDSWTSAAIAAMNRAFLDAAALGVTVLAAAGDSGSTDGEQDGLYHVDFPAASPYV 187 Query: 342 IQVAALDYYGGTFRVAG-------------------------FSSRSDGVSVGAPGVTIL 376 + R+A + ++ PG + Sbjct: 188 LACGGTRLVASGGRIAQETVWNDGPDGGATGGGVSRIFPLPAWQEHANVPPSANPGASSG 247 Query: 377 STVPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQK--------FPN 428 VP D G G GTS AP +VA + QK P Sbjct: 248 RGVP--DLAGNADPATGYEVVIDGEATVIGGTSAVAPLFAALVARINQKLGKAVGYLNPT 305 Query: 429 A--KPWQIRKLLENTAFDF--------NGNGWDHDTGYGLVKLDAALQGPLPTQGGVEE 477 P + + D G GWD TG G LQ LP+ + Sbjct: 306 LYQLPADVFHDITEGNNDIANRAQIYQAGPGWDPCTGLGSPIGVRLLQALLPSASQPQP 364 >1T1I-A nrPDB Length = 364 Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 59/285 (20%), Positives = 81/285 (28%), Gaps = 66/285 (23%) Query: 249 APGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWATDHGAKVMNHSWGGWGYS------ 302 APGAKI N G + H +++ S GG S Sbjct: 90 APGAKIAVY--------FAPNTDAGFLNAITTAVHDPTHKPSIVSISAGGPEDSWAPASI 141 Query: 303 YTMKEAFDYAMEHGVVMVVSAGNNTSDSHHQ-------YPAGYPGVIQVAALDYYGGTFR 355 M AF A GV ++ +AG++ S Q +PA P V+ R Sbjct: 142 AAMNRAFLDAAALGVTVLAAAGDSGSTDGEQDGLYHVDFPAASPYVLACGGTRLVASAGR 201 Query: 356 V-------------------------AGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGH 390 + + R++ PG VP D G Sbjct: 202 IERETVWNDGPDGGSTGGGVSRIFPLPSWQERANVPPSANPGAGSGRGVP--DVAGNADP 259 Query: 391 NENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQK--------FPNA--KPWQIRKLLEN 440 G GTS AP +VA + QK P P ++ + Sbjct: 260 ATGYEVVIDGETTVIGGTSAVAPLFAALVARINQKLGKPVGYLNPTLYQLPPEVFHDITE 319 Query: 441 TAFDF--------NGNGWDHDTGYGLVKLDAALQGPLPTQGGVEE 477 D G GWD TG G LQ LP+ + Sbjct: 320 GNNDIANRARIYQAGPGWDPCTGLGSPIGIRLLQALLPSASQAQP 364 >3EDY-A nrPDB Length = 544 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 36/244 (14%), Positives = 67/244 (27%), Gaps = 63/244 (25%) Query: 289 AKVMNHSWGGWGYS------YTMKEAFDYAMEHGVVMVVSAGNNTSDSH---------HQ 333 V S+G S + A G+ ++ ++G++ + Sbjct: 299 PHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPT 358 Query: 334 YPAGYPGVIQVAALDYYGG---TFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGH 390 +PA P V V + T + + S +V V S Sbjct: 359 FPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLP 418 Query: 391 NENVPATNGGTYD-------------------YYQGTSMAAPHVTGVVAVLLQK------ 425 + +G Y + GTS + P G+++++ + Sbjct: 419 PSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGR 478 Query: 426 ------FPNAKPW------QIRKLLENTAFD--------FNGNGWDHDTGYGLVKLDAAL 465 P + + + D +G GWD TG+G A L Sbjct: 479 PPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALL 538 Query: 466 QGPL 469 + L Sbjct: 539 KTLL 542 >2ZY2-A nrPDB Length = 544 Score = 33.5 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 41/156 (26%), Positives = 59/156 (37%), Gaps = 16/156 (10%) Query: 34 LASLPEIKSQG----YHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELPQ 89 L+ LPE + Y L ++R + + DR D V A+N L PQ Sbjct: 338 LSQLPESAKKALDHRYRSLLPDVRS---------LKFIDRLVADSRVVALNHTAGLSTPQ 388 Query: 90 IKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGLN 149 +V + + + D K + IR E + REL P + PN Y N Sbjct: 389 -QVQMVLFSLFALMDEADAYKQALKQLIRRREATLYRELGMPPLENPNSVNYYTLIDLQN 447 Query: 150 STARDYGEELSNELWGLEAIGVTQQLWEEASGTNII 185 T R YGE S W ++ L+ A T I+ Sbjct: 448 VTCRLYGEAFS--QWAVQQSSTGDMLFRVADETGIV 481 >1VMA-A nrPDB Length = 306 Score = 32.7 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 282 IWATDHGAKVMNHSWGGWGYSYTMKE-AFDYAMEHGVVMVVSAG 324 IW GA V++HS G + A A VV++ +AG Sbjct: 153 IWGERVGATVISHSEGADPAAVAFDAVAHALARNKDVVIIDTAG 196 >5C3R-A nrPDB Length = 343 Score = 32.4 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%) Query: 34 LASLPEIKSQGYHILFGELRDGEYTE-GKILVGYNDRSEVDKIVKAVNGKVVLELPQIKV 92 L P +KS+ + I G++R GE+T+ G I + + D S VK+ NG+ + P Sbjct: 193 LLHYPAVKSEVFKINPGQVRAGEHTDYGSITLLFQD-SRGGLQVKSPNGQFIDATPIENT 251 Query: 93 VSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTV-----VKPNPDMYKIRKPG 147 V + + + + D IK+ R VEP + ++ P PN Y PG Sbjct: 252 VVVNAGDLLARWSNDTIKSTVH---RVVEPPKQEDVHPPRYSIAYFCNPNHKSYIEAIPG 308 >1OFM-A nrPDB Length = 481 Score = 32.4 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 531 GGPDHWDRALAPYDGESIPGGYAIALRMAEERQASF 566 G P WD + PY + +PG YA+ R++ +R A F Sbjct: 437 GKPLSWDE-VRPYWLKEMPGTYALTARLSADRAAKF 471 >2BGN-E nrPDB Length = 363 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 59/155 (38%), Gaps = 34/155 (21%) Query: 105 AYDKIKALALKGIRYVEPSYKRELIKPTVVKPNP-----------DMYKIRKPGLNSTAR 153 AY+ ++ A G+ YVE Y L+ + V+P P ++ + GL R Sbjct: 83 AYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGER 142 Query: 154 DYGEELSNEL--------WGLEAIGVTQQLWEEASGTNIIVAVVDTGVDGTHPDLEGQVI 205 D+G ++ + L W E + + ++ E+ +VA+ DL G Sbjct: 143 DFGVKVRSILCCMRHQPSWSSEVVELCKKYREQ-----TVVAI----------DLAGDET 187 Query: 206 AGYRPAFDEELPAGTDSSYGGSHGTHVAGTIAAKK 240 F + A ++ G H T AG + + Sbjct: 188 IEGSSLFPGHVQAYAEAVKSGVHRTVHAGEVGSAN 222 >1QQ9-A nrPDB Length = 284 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 36/98 (36%), Gaps = 7/98 (7%) Query: 323 AGNNTSDSHHQYPAGYPGVIQVAA-LDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPG 381 A NN + H P V V A LD G T + F+S A G +++ PG Sbjct: 20 AANNGGNRAHGRPGYKASVDYVKAKLDAAGYTTTLQQFTSGG------ATGYNLIANWPG 73 Query: 382 EDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVV 419 D ++ + + G G+ AA T + Sbjct: 74 GDPNKVLMAGAHLDSVSSGAGINDNGSGSAAVLETALA 111 >3SUC-A nrPDB Length = 772 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 39/200 (19%), Positives = 66/200 (33%), Gaps = 27/200 (13%) Query: 284 ATDHGAKVMNHSWGGWGYS---YTMKEAFDYAMEHGV--------------------VMV 320 +++G V+ S GG + T+ + Y + G V + Sbjct: 373 NSENGIYVIGGSRGGDAVNISNVTLNNSGRYGVSIGSGIENVSITNISGIGDGINSPVAL 432 Query: 321 VSAGNNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGF--SSRSDGVSVGAPGVTILST 378 VS N+ + GYP V +VA DY G G +S + + + G + ST Sbjct: 433 VSTINSNPEISGLSSIGYPTVARVAGTDYNDGLTLFNGAFRASTTSSGKIHSEGFIMGST 492 Query: 379 VPGEDSIGYEGHNENVPATNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLL 438 E S+ G + + G+S G +L Q L+ Sbjct: 493 SGCEASVSKSGVLTSSSSKTSSERSLIAGSS--TSEAKGTYNTILGSLGAVADEQFAALI 550 Query: 439 ENTAFDFNGNGWDHDTGYGL 458 + +GN + YG+ Sbjct: 551 SASQSRASGNHNLILSSYGI 570 >4QQ1-A nrPDB Length = 543 Score = 30.0 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 35/97 (36%), Gaps = 10/97 (10%) Query: 434 IRKLLENTAFDFNGNGWDHDTGYGLVKLDAALQGPLPTQ--GGVEEFQVVVTD------- 484 +R + + A N T YG + + G Q G EF V + Sbjct: 390 VRTPVSDVAARTEANAKYRGTWYGYIANGTSWSGEASNQEGGNRAEFDVDFSTKKISGTL 449 Query: 485 -AKGNFGVPTVFVSMMRDNGSCYYAKTGPDGIARFPH 520 AK +M++DNG AKTG +G A P Sbjct: 450 TAKDRTSPAFTITAMIKDNGFSGVAKTGENGFALDPQ 486 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.132 0.375 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,776,640 Number of Sequences: 36641 Number of extensions: 1283337 Number of successful extensions: 4148 Number of sequences better than 10.0: 77 Number of HSP's better than 10.0 without gapping: 112 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 3475 Number of HSP's gapped (non-prelim): 186 length of query: 699 length of database: 10,336,785 effective HSP length: 104 effective length of query: 595 effective length of database: 6,526,121 effective search space: 3883041995 effective search space used: 3883041995 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (28.9 bits)