BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q93088 (406 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1LT8-A nrPDB 824 0.0 1UMY-A nrPDB 797 0.0 1Q7Q-A nrPDB 70 1e-12 4CCZ-A nrPDB 56 2e-08 5DML-A nrPDB 51 1e-06 1F8S-A nrPDB 31 1.2 4V6U-AD nrPDB 29 3.7 2UYY-A nrPDB 28 7.0 >1LT8-A nrPDB Length = 406 Score = 824 bits (2128), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/406 (98%), Positives = 400/406 (98%) Query: 1 MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 M PVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAA DIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAAADIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 GVSQTPSYLS KSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP Sbjct: 121 GVSQTPSYLSAKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARL 240 VAATM IGPEGDLHGVPPGE AVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAA+L Sbjct: 181 VAATMAIGPEGDLHGVPPGEAAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQL 240 Query: 241 KAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KAHLMSQPLAYHTPD NKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAHLMSQPLAYHTPDANKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 Query: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ 406 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ Sbjct: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ 406 >1UMY-A nrPDB Length = 407 Score = 797 bits (2059), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/405 (93%), Positives = 392/405 (96%) Query: 1 MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 M P+ GKKAK+GILERLNAGE+VIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPIAGKKAKRGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYV EKISGQ+VNEAACDIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 GVSQTPSYLSCKSETEVKK+F QQLEVFMKKNVDFLIAEYFEHVEEAVWAVE L SGKP Sbjct: 121 GVSQTPSYLSCKSETEVKKIFHQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKTSGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARL 240 +AATMCIGPEGDLHGV PGECAVRLVKAGA+I+GVNCHFDP+ SL+T+KLMKEGLEAARL Sbjct: 181 IAATMCIGPEGDLHGVSPGECAVRLVKAGAAIVGVNCHFDPSTSLQTIKLMKEGLEAARL 240 Query: 241 KAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KA+LMSQPLAYHTPDC KQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPW+RARARKEYW+NLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 Query: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKS 405 RPYNPSMSKPD WGVTKG AELMQQKEATTEQQL+ LFEKQKFKS Sbjct: 361 RPYNPSMSKPDAWGVTKGAAELMQQKEATTEQQLRALFEKQKFKS 405 >1Q7Q-A nrPDB Length = 566 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 75/301 (24%), Positives = 130/301 (43%), Gaps = 32/301 (10%) Query: 14 LERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT 73 + +L + +++ DG + K GY E ++ P+ V ++HR ++ +GS+V+ T Sbjct: 7 VSKLLSERVLLLDGAYGTEFMKYGY---DDLPEELNIKAPDVVLKVHRSYIESGSDVILT 63 Query: 74 FTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAGGVSQT---PSYLS 130 TF A+ KL G + +K+ + A IAR+ A G+ LV G + T P L Sbjct: 64 NTFGATRMKLRKHG--LEDKL--DPIVRNAVRIARRAA--GEKLVFGDIGPTGELPYPLG 117 Query: 131 CKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPV--AATMCIG 188 E + F + +E+ +++ VD +I E F + E AV + V A M Sbjct: 118 STLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFD 177 Query: 189 PEG-DLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQ 247 +G L G P A+ + +G+NC P L + + + + L+ + Sbjct: 178 EKGRSLTGTDPANFAITFDELDIDALGINCSLGPEEILPIFQELSQYTD-----KFLVVE 232 Query: 248 PLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHI 307 P A + ++ + + L+P D + Y LGV GGCCG P H+ Sbjct: 233 PNA-------GKPIVENGKTVYPLKPH-----DFAVHIDSYYELGVNIFGGCCGTTPEHV 280 Query: 308 R 308 + Sbjct: 281 K 281 >4CCZ-A nrPDB Length = 644 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 70/306 (22%), Positives = 133/306 (43%), Gaps = 48/306 (15%) Query: 49 AVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIAR 108 ++ P+ + Q+H+E+L AG+++++T TF ++ + +Y LE ++ +N + +AR Sbjct: 58 SITQPDVIYQIHKEYLLAGADIIETNTFSSTSIA---QADYGLEHLA-YRMNMCSAGVAR 113 Query: 109 QVADEGDA------LVAGGVSQTPSYLSCKSET-----------EVKKVFLQQLEVFMKK 151 + A+E VAG + T LS E+ + + +Q + + Sbjct: 114 KAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDG 173 Query: 152 NVDFLIAEYF---EHVEEAVWAVETLIA---SGKPVAAT-MCIGPEGDLHGVPPGECAVR 204 VD L+ E + + A++A++ L + +P+ + + G GE V Sbjct: 174 GVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVI 233 Query: 205 LVKAGASI-IGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFID 263 V G + IG+NC ++++ + A+++ P A P+ F D Sbjct: 234 SVSHGEPLCIGLNCALGAAEMRPFIEIIGKC-----TTAYVLCYPNA-GLPNT----FGD 283 Query: 264 LPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPP 323 E P + ++ +A + V +GGCCG P HIR IAE + + +PP Sbjct: 284 YDETPSMMAKH------LKDFAMDGL---VNIVGGCCGSTPDHIREIAEAVKNCKPRVPP 334 Query: 324 ASEKHG 329 A+ G Sbjct: 335 ATAFEG 340 >5DML-A nrPDB Length = 310 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 21/178 (11%) Query: 17 LNAGEIVIGDGGFVFALEKRGYVKAGP-WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFT 75 L+ +I++ DG LE RG A W+ + VE+PE +R++H ++ RAG+ T + Sbjct: 11 LDKQDILLLDGAMATELEARGCNLADSLWSAKVLVENPELIREVHLDYYRAGAQCAITAS 70 Query: 76 FYASEDKLENRGNYVLEKISGQEVNEAACDIARQVAD--------EGDALVAGGVSQTPS 127 + A+ RG L++ + + + ++AR+ + G LVAG V + Sbjct: 71 YQATPAGFAARG---LDEAQSKALIGKSVELARKAREAYLAENPQAGTLLVAGSVGPYGA 127 Query: 128 YLSCKSE--------TEVKKVFLQ-QLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIA 176 YL+ SE E + F + ++E + D L E + E E L A Sbjct: 128 YLADGSEYRGDYHCSVEAFQAFHRPRVEALLDAGADLLACETLPNFSEIEALAELLTA 185 >1F8S-A nrPDB Length = 498 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 16/99 (16%) Query: 273 PRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWG 332 P V +W + KYA +GG F PY + ++ L +G + A E Sbjct: 414 PSVIQKWSLDKYA----------MGGITTFTPYQFQHFSDPLTASQGRIYFAGEYTAQAH 463 Query: 333 SGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPD 371 +D K +RA AR ++ +AS P +S + Sbjct: 464 GWIDSTIKSGLRA-AR-----DVNLASENPSGIHLSNDN 496 >4V6U-AD nrPDB Length = 180 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Query: 47 EAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDI 106 +A +E + + +L R L V+ ED LE R L+ I ++ Sbjct: 65 QAEIEREQLLARLKRLGLLPEDAVLDDVLSLTIEDILERR----LQTIVYKKGLARTMRQ 120 Query: 107 ARQVADEGDALVAGGVSQTPSYLSCKSETEV 137 ARQ+ G V G + ++PSYL K E + Sbjct: 121 ARQLIVHGHIEVNGQIIRSPSYLVLKEEEDT 151 >2UYY-A nrPDB Length = 316 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 182 AATMCIGPEGDLHGVPPGECAVRLVKAGASII 213 A + +GP G L G+ PG+C V + A + Sbjct: 100 AKDLVLGPSGVLQGIRPGKCYVDMSTVDADTV 131 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1UMY-A nrPDB 688 0.0 1LT8-A nrPDB 683 0.0 1Q7Q-A nrPDB 337 4e-93 4CCZ-A nrPDB 314 4e-86 5DML-A nrPDB 209 2e-54 Sequences not found previously or not previously below threshold: 4QI6-A nrPDB 37 0.017 4QI5-A nrPDB 37 0.017 3AJB-A nrPDB 35 0.066 1VRD-A nrPDB 33 0.25 5EF4-A nrPDB 32 0.45 3DSD-A nrPDB 31 0.90 6FVU-L nrPDB 31 1.4 6EF0-L nrPDB 30 1.9 5WVI-L nrPDB 30 1.9 3A0V-A nrPDB 29 3.0 2OLS-A nrPDB 29 3.0 1WYD-A nrPDB 29 4.8 6B5K-A nrPDB 29 5.1 2Z3V-A nrPDB 28 8.2 CONVERGED! >1UMY-A nrPDB Length = 407 Score = 688 bits (1776), Expect = 0.0, Method: Composition-based stats. Identities = 377/405 (93%), Positives = 392/405 (96%) Query: 1 MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 M P+ GKKAK+GILERLNAGE+VIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPIAGKKAKRGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYV EKISGQ+VNEAACDIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 GVSQTPSYLSCKSETEVKK+F QQLEVFMKKNVDFLIAEYFEHVEEAVWAVE L SGKP Sbjct: 121 GVSQTPSYLSCKSETEVKKIFHQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKTSGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARL 240 +AATMCIGPEGDLHGV PGECAVRLVKAGA+I+GVNCHFDP+ SL+T+KLMKEGLEAARL Sbjct: 181 IAATMCIGPEGDLHGVSPGECAVRLVKAGAAIVGVNCHFDPSTSLQTIKLMKEGLEAARL 240 Query: 241 KAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KA+LMSQPLAYHTPDC KQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPW+RARARKEYW+NLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 Query: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKS 405 RPYNPSMSKPD WGVTKG AELMQQKEATTEQQL+ LFEKQKFKS Sbjct: 361 RPYNPSMSKPDAWGVTKGAAELMQQKEATTEQQLRALFEKQKFKS 405 >1LT8-A nrPDB Length = 406 Score = 683 bits (1763), Expect = 0.0, Method: Composition-based stats. Identities = 399/406 (98%), Positives = 400/406 (98%) Query: 1 MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 M PVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAA DIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAAADIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 GVSQTPSYLS KSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP Sbjct: 121 GVSQTPSYLSAKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARL 240 VAATM IGPEGDLHGVPPGE AVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAA+L Sbjct: 181 VAATMAIGPEGDLHGVPPGEAAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQL 240 Query: 241 KAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KAHLMSQPLAYHTPD NKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAHLMSQPLAYHTPDANKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 Query: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ 406 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ Sbjct: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ 406 >1Q7Q-A nrPDB Length = 566 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 76/312 (24%), Positives = 133/312 (42%), Gaps = 32/312 (10%) Query: 14 LERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT 73 + +L + +++ DG + K GY E ++ P+ V ++HR ++ +GS+V+ T Sbjct: 7 VSKLLSERVLLLDGAYGTEFMKYGY---DDLPEELNIKAPDVVLKVHRSYIESGSDVILT 63 Query: 74 FTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAGGVSQT---PSYLS 130 TF A+ KL G + +K+ + A IAR+ A G+ LV G + T P L Sbjct: 64 NTFGATRMKLRKHG--LEDKL--DPIVRNAVRIARRAA--GEKLVFGDIGPTGELPYPLG 117 Query: 131 CKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVA--ATMCIG 188 E + F + +E+ +++ VD +I E F + E AV + V A M Sbjct: 118 STLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFD 177 Query: 189 PEGD-LHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQ 247 +G L G P A+ + +G+NC P L + + + + L+ + Sbjct: 178 EKGRSLTGTDPANFAITFDELDIDALGINCSLGPEEILPIFQELSQYTD-----KFLVVE 232 Query: 248 PLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHI 307 P A + ++ + + L+P D + Y LGV GGCCG P H+ Sbjct: 233 PNA-------GKPIVENGKTVYPLKPH-----DFAVHIDSYYELGVNIFGGCCGTTPEHV 280 Query: 308 RAIAEELAPERG 319 + + L + Sbjct: 281 KLFRKVLGNRKP 292 >4CCZ-A nrPDB Length = 644 Score = 314 bits (805), Expect = 4e-86, Method: Composition-based stats. Identities = 78/361 (21%), Positives = 149/361 (41%), Gaps = 62/361 (17%) Query: 8 KAKKGILERLNAGEIVIGDGGFVFALEK--------RGYVKAGPWTPE------AAVEHP 53 K + + + I++ DGG +++ RG P ++ P Sbjct: 3 KTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQP 62 Query: 54 EAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADE 113 + + Q+H+E+L AG+++++T TF ++ + +Y LE ++ +N + +AR+ A+E Sbjct: 63 DVIYQIHKEYLLAGADIIETNTFSSTSIA---QADYGLEHLA-YRMNMCSAGVARKAAEE 118 Query: 114 GDA------LVAGGVSQTPSYLSCKSETE-----------VKKVFLQQLEVFMKKNVDFL 156 VAG + T LS E + + + +Q + + VD L Sbjct: 119 VTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 178 Query: 157 IAEYF---EHVEEAVWAVETLIA---SGKPVAAT-MCIGPEGDLHGVPPGECAVRLVKAG 209 + E + + A++A++ L + +P+ + + G GE V V G Sbjct: 179 LIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHG 238 Query: 210 ASI-IGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFP 268 + IG+NC ++++ + A+++ P A P+ F D E P Sbjct: 239 EPLCIGLNCALGAAEMRPFIEIIGKC-----TTAYVLCYPNA-GLPNT----FGDYDETP 288 Query: 269 FGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKH 328 + ++ +A + V +GGCCG P HIR IAE + + +PPA+ Sbjct: 289 SMMAKH------LKDFAMDGL---VNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFE 339 Query: 329 G 329 G Sbjct: 340 G 340 >5DML-A nrPDB Length = 310 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 75/316 (23%), Positives = 125/316 (39%), Gaps = 42/316 (13%) Query: 17 LNAGEIVIGDGGFVFALEKRGYVKAGP-WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFT 75 L+ +I++ DG LE RG A W+ + VE+PE +R++H ++ RAG+ T + Sbjct: 11 LDKQDILLLDGAMATELEARGCNLADSLWSAKVLVENPELIREVHLDYYRAGAQCAITAS 70 Query: 76 FYASEDKLENRGNYVLEKISGQEVNEAACDIARQVAD--------EGDALVAGGVSQTPS 127 + A+ RG L++ + + + ++AR+ + G LVAG V + Sbjct: 71 YQATPAGFAARG---LDEAQSKALIGKSVELARKAREAYLAENPQAGTLLVAGSVGPYGA 127 Query: 128 YLSCKSE--------TEVKKVFLQ-QLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASG 178 YL+ SE E + F + ++E + D L E + E E L A Sbjct: 128 YLADGSEYRGDYHCSVEAFQAFHRPRVEALLDAGADLLACETLPNFSEIEALAELLTAYP 187 Query: 179 KPVA-ATMCIGPEGDLHGVPPGECAVRLVKAGAS---IIGVNCHFDPTISLKTVKLMKEG 234 + A + + L P V L+ AG +G+NC I+L+ + Sbjct: 188 RARAWFSFTLRDSEHLSDGTPLRDVVALL-AGYPQVVALGINC-----IALENTTAALQH 241 Query: 235 LEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVR 294 L + L+ P + D + + E A + Y + G R Sbjct: 242 LHGLTVLP-LVVYPNSGEHYDAVSKTWHHHGE-------HCAQ---LADYLPQWQAAGAR 290 Query: 295 YIGGCCGFEPYHIRAI 310 IGGCC P I A+ Sbjct: 291 LIGGCCRTTPADIAAL 306 >4QI6-A nrPDB Length = 807 Score = 36.7 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 26/182 (14%), Positives = 59/182 (32%), Gaps = 35/182 (19%) Query: 37 GYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT--FTFYASEDKLENRGNYVLEKI 94 GY + + HP+ V +F A + +++ ++ S + + + + Sbjct: 525 GYNLDDHLNTDTVISHPDVVF---YDFYEAWDDPIESDKNSYLESRTGILAQAAPNIGPM 581 Query: 95 SGQEVNEAACDIARQVADEGDALVAGGVSQ------------------------TPSYLS 130 +E+ A I RQ+ + A V G + TPS + Sbjct: 582 FWEEIVGAD-GIVRQL--QWTARVEGSLGAPNGHTMTMSQYLGRGATSRGRMTITPSLTT 638 Query: 131 CKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPE 190 S+ K + E ++ ++ + ++V W + + +M + P Sbjct: 639 IVSDVPYLKDPNDK-EAVIQGIIN--LQNALQNVANLTWLFPNSTITPREYVESMVVSPS 695 Query: 191 GD 192 Sbjct: 696 NR 697 >4QI5-A nrPDB Length = 585 Score = 36.7 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 26/182 (14%), Positives = 59/182 (32%), Gaps = 35/182 (19%) Query: 37 GYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT--FTFYASEDKLENRGNYVLEKI 94 GY + + HP+ V +F A + +++ ++ S + + + + Sbjct: 303 GYNLDDHLNTDTVISHPDVVF---YDFYEAWDDPIESDKNSYLESRTGILAQAAPNIGPM 359 Query: 95 SGQEVNEAACDIARQVADEGDALVAGGVSQ------------------------TPSYLS 130 +E+ A I RQ+ + A V G + TPS + Sbjct: 360 FWEEIVGAD-GIVRQL--QWTARVEGSLGAPNGHTMTMSQYLGRGATSRGRMTITPSLTT 416 Query: 131 CKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPE 190 S+ K + E ++ ++ + ++V W + + +M + P Sbjct: 417 IVSDVPYLKDPNDK-EAVIQGIIN--LQNALQNVANLTWLFPNSTITPREYVESMVVSPS 473 Query: 191 GD 192 Sbjct: 474 NR 475 >3AJB-A nrPDB Length = 330 Score = 34.8 bits (78), Expect = 0.066, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 47/150 (31%), Gaps = 6/150 (4%) Query: 142 LQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGEC 201 + K L+ Y EE AV+ S + + + D+ P Sbjct: 176 HKSSSWINKDGSKPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFST 235 Query: 202 AV-RLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQG 260 + + G S + N T + ++ G L + +S PLA P N Q Sbjct: 236 VLNTCLNRGFSRLLDNMA---EFFRPTEQDLQHGNSMNSLSS--VSLPLAKIIPIVNGQI 290 Query: 261 FIDLPEFPFGLEPRVATRWDIQKYAREAYN 290 E P + T ++ +A Y Sbjct: 291 HSVCSETPSHFVQDLLTMEQVKDFAANVYE 320 >1VRD-A nrPDB Length = 494 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 37/96 (38%), Gaps = 16/96 (16%) Query: 112 DEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFE-HVEEAVWA 170 ++G LV V +P + +++E +K VD ++ + H + Sbjct: 222 EKGRLLVGAAVGTSPETM-------------ERVEKLVKAGVDVIVIDTAHGHSRRVIET 268 Query: 171 VETLIA--SGKPVAATMCIGPEGDLHGVPPGECAVR 204 +E + A PV A PEG + G AV+ Sbjct: 269 LEMIKADYPDLPVVAGNVATPEGTEALIKAGADAVK 304 >5EF4-A nrPDB Length = 385 Score = 32.1 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 12/104 (11%) Query: 275 VATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERG--FLPPASEKHGSWG 332 VAT + + + Y+ GV G CG EP H I E+G F + +WG Sbjct: 259 VATGIQLSGHGLQFYSEGV--YTGDCGTEPNHGVGIVGYGENEKGIKFWTVKNSWGPTWG 316 Query: 333 SGLDMHTKPWVRARARKEYWENLRIASGRPY----NPSMSKPDG 372 +H ++ ARKE + + S P NP P+G Sbjct: 317 EKGYIH----LQRGARKEGLCGVAMHSSFPIMNDPNPPKDDPNG 356 >3DSD-A nrPDB Length = 349 Score = 30.9 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 26/59 (44%), Gaps = 9/59 (15%) Query: 134 ETEVKKVFLQQLEVFMKKNVDFLIAE---------YFEHVEEAVWAVETLIASGKPVAA 183 E E + F LE+ +++NVDF++ +++A+ ++ PV A Sbjct: 22 EEEFAEAFKNALEIAVQENVDFILIAGDLFHSSRPSPGTLKKAIALLQIPKEHSIPVFA 80 >6FVU-L nrPDB Length = 388 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 40/119 (33%), Gaps = 14/119 (11%) Query: 143 QQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECA 202 +Q E+ + L E + E +E + + + P+G L PPG Sbjct: 126 EQGEITFD-GIGGLT----EQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGK 180 Query: 203 VRLVKAGASIIGVNCHFDPT---------ISLKTVKLMKEGLEAARLKAHLMSQPLAYH 252 L KA A+ IG N F P S + ++ M + M + A Sbjct: 181 TLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIG 239 >6EF0-L nrPDB Length = 273 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 40/119 (33%), Gaps = 14/119 (11%) Query: 143 QQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECA 202 +Q E+ + L E + E +E + + + P+G L PPG Sbjct: 11 EQGEITFD-GIGGLT----EQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGK 65 Query: 203 VRLVKAGASIIGVNCHFDPT---------ISLKTVKLMKEGLEAARLKAHLMSQPLAYH 252 L KA A+ IG N F P S + ++ M + M + A Sbjct: 66 TLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIG 124 >5WVI-L nrPDB Length = 437 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 40/119 (33%), Gaps = 14/119 (11%) Query: 143 QQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECA 202 +Q E+ + L E + E +E + + + P+G L PPG Sbjct: 174 EQGEITFD-GIGGLT----EQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGK 228 Query: 203 VRLVKAGASIIGVNCHFDPT---------ISLKTVKLMKEGLEAARLKAHLMSQPLAYH 252 L KA A+ IG N F P S + ++ M + M + A Sbjct: 229 TLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIG 287 >3A0V-A nrPDB Length = 96 Score = 29.4 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 18/43 (41%) Query: 143 QQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATM 185 +QL K+NV + EE E++ + +PV M Sbjct: 22 EQLFGLKKENVLGRRLKDLPDFEEIGSVAESVFENKEPVFLNM 64 >2OLS-A nrPDB Length = 794 Score = 29.4 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 55/342 (16%), Positives = 102/342 (29%), Gaps = 35/342 (10%) Query: 4 VGGKKAKKGILERLNAGEIVIGDGGFVFALEK-RGYVKAGPWTPEAAVEHPEAVRQLHRE 62 VGGK A G + + V GGF E R ++ + + + + E Sbjct: 20 VGGKNASLGEMISQLTEKGVRVPGGFATTAEAYRAFLAHNGLSERISAALAKLDVEDVAE 79 Query: 63 FLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIA-RQVADEGDALVAGG 121 R G + Q ++L+ K+ A +A R A D A Sbjct: 80 LARVGKEIRQWILDTPFPEQLDAEIEAAWNKMVADA-GGADISVAVRSSATAEDLPDASF 138 Query: 122 VSQTPSYLSCKSETEVKKVFLQQLEVFM-KKNVDFLIAEYFEH-VEEAVWAVETL----- 174 Q ++L+ VK+ + + + + + FEH + V+ + Sbjct: 139 AGQQETFLNINGLDNVKEAMHHVFASLYNDRAISYRVHKGFEHDIVALSAGVQRMVRSDS 198 Query: 175 ----------IASGKP----VAATMCIGPEGDLHGVPPGECAVR--LVKAGASIIGVNCH 218 SG V ++ +G V P E V +KAG I + Sbjct: 199 GASGVMFTLDTESGYDQVVFVTSSYGLGENVVQGAVNPDEFYVFKPTLKAGKPAI-LRKT 257 Query: 219 FDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATR 278 E ++ + D + +L + +E Sbjct: 258 MGSKHIKMIFTDKAEAGKSVTNVDVPEEDRNRFSITD---EEITELAHYALTIEKHYGRP 314 Query: 279 WDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGF 320 DI+ + R+ + + + P +++ E R F Sbjct: 315 MDIE-WGRDGLDGKLYILQA----RPETVKSQEEGNRNLRRF 351 >1WYD-A nrPDB Length = 429 Score = 28.6 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 43/118 (36%), Gaps = 7/118 (5%) Query: 221 PTISLKTVKL-MKEGLEAARLKAHLMSQPLAYHTPDCN------KQGFIDLPEFPFGLEP 273 P + + +L E +E R K + + TP+ K+ + ++P P Sbjct: 269 PEVKIPIKRLKYTEAIEILRSKGYNIKFGDDIGTPELRILNEELKEDLYFIVDWPSDARP 328 Query: 274 RVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSW 331 E+++L +++ G H R + EE ++G P + E W Sbjct: 329 FYTKSKSENPELSESFDLIYKFLEIVSGSTRNHKREVLEEALKKKGLKPESFEFFLKW 386 >6B5K-A nrPDB Length = 296 Score = 28.6 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 24/57 (42%) Query: 5 GGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHR 61 G KK+ +G E ++ + G + RG T ++ ++ + VR L R Sbjct: 185 GLKKSARGEYEITEVNQVYLNQGRLAVEVLARGTAWLDTGTFDSLLDAADFVRTLER 241 >2Z3V-A nrPDB Length = 137 Score = 27.8 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 24/76 (31%), Gaps = 12/76 (15%) Query: 116 ALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKK-----NV---DFLIAEYFEHVEEA 167 +V P YL E + L++ E +++ V D L+ E A Sbjct: 33 LIVVHAYEPVPDYLGEPFFEEALRRRLERAEGVLEEARALTGVPKEDALLLEGVP----A 88 Query: 168 VWAVETLIASGKPVAA 183 ++ A + Sbjct: 89 EAILQAARAEKADLIV 104 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.124 0.331 Lambda K H 0.267 0.0375 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,256,846 Number of Sequences: 36641 Number of extensions: 555570 Number of successful extensions: 1591 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1548 Number of HSP's gapped (non-prelim): 36 length of query: 406 length of database: 10,336,785 effective HSP length: 99 effective length of query: 307 effective length of database: 6,709,326 effective search space: 2059763082 effective search space used: 2059763082 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 60 (27.8 bits)