BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q92947 (438 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1SIR-A nrPDB 820 0.0 4W9U-A nrPDB 531 e-151 3GNC-A nrPDB 516 e-147 3SF6-A nrPDB 377 e-105 2EBA-A nrPDB 374 e-104 3SWO-A nrPDB 341 4e-94 2IX5-A nrPDB 231 4e-61 4L1F-A nrPDB 207 6e-54 5LNX-A nrPDB 205 4e-53 5OL2-C nrPDB 190 8e-49 1BUC-A nrPDB 189 2e-48 2DVL-A nrPDB 186 2e-47 3OWA-A nrPDB 181 7e-46 2Z1Q-A nrPDB 178 3e-45 2VIG-A nrPDB 177 9e-45 1JQI-A nrPDB 177 9e-45 4KTO-A nrPDB 176 3e-44 4O5M-A nrPDB 175 3e-44 4U83-A nrPDB 172 2e-43 4N5F-A nrPDB 169 2e-42 2JIF-A nrPDB 159 2e-39 4M9A-A nrPDB 158 5e-39 3MPI-A nrPDB 157 6e-39 1IVH-A nrPDB 157 8e-39 1UKW-A nrPDB 157 1e-38 3B96-A nrPDB 151 6e-37 6FAH-C nrPDB 144 6e-35 2A1T-A nrPDB 140 1e-33 3MDE-A nrPDB 139 3e-33 3NF4-A nrPDB 137 7e-33 6ES9-A nrPDB 135 2e-32 2PG0-A nrPDB 134 7e-32 2CX9-A nrPDB 133 1e-31 3PFD-A nrPDB 127 1e-29 4IV6-A nrPDB 124 9e-29 1RX0-A nrPDB 120 9e-28 5IDU-A nrPDB 116 2e-26 4IRN-A nrPDB 115 5e-26 5ZW7-A nrPDB 114 9e-26 5JSC-A nrPDB 104 7e-23 1R2J-A nrPDB 95 5e-20 3R7K-A nrPDB 92 4e-19 3P4T-A nrPDB 89 4e-18 6CY8-B nrPDB 74 9e-14 5AHS-A nrPDB 70 2e-12 5EZ3-A nrPDB 67 2e-11 4HR3-A nrPDB 64 2e-10 4RM7-A nrPDB 60 2e-09 2WBI-A nrPDB 58 8e-09 4X28-A nrPDB 56 3e-08 5Y9D-A nrPDB 52 5e-07 5YS9-A nrPDB 50 1e-06 2FON-A nrPDB 49 4e-06 3U33-A nrPDB 48 7e-06 4XVX-A nrPDB 47 2e-05 5GJ7-A nrPDB 47 2e-05 4ZYJ-A nrPDB 46 4e-05 5K3J-A nrPDB 45 7e-05 1W07-A nrPDB 44 1e-04 4X28-D nrPDB 43 3e-04 1IS2-A nrPDB 37 0.015 5K3G-A nrPDB 37 0.017 3M9V-A nrPDB 35 0.083 4JEK-A nrPDB 33 0.20 5T33-G nrPDB 31 0.95 1J49-A nrPDB 29 4.4 4GO4-A nrPDB 29 5.1 6QM4-A nrPDB 28 5.6 1IHU-A nrPDB 28 5.9 5MLG-A nrPDB 28 9.9 >1SIR-A nrPDB Length = 394 Score = 820 bits (2118), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/394 (100%), Positives = 394/394 (100%) Query: 45 RPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELG 104 RPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELG Sbjct: 1 RPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELG 60 Query: 105 VLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY 164 VLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY Sbjct: 61 VLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY 120 Query: 165 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV 224 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV Sbjct: 121 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV 180 Query: 225 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG 284 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG Sbjct: 181 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG 240 Query: 285 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 344 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT Sbjct: 241 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 300 Query: 345 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 404 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA Sbjct: 301 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 360 Query: 405 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK 438 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK Sbjct: 361 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK 394 >4W9U-A nrPDB Length = 395 Score = 531 bits (1369), Expect = e-151, Method: Compositional matrix adjust. Identities = 259/394 (65%), Positives = 308/394 (78%), Gaps = 5/394 (1%) Query: 44 SRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGEL 103 SR F W+DP +LEEQLT DE +IRD+ + + + L+PR+ A E E+ MG+ Sbjct: 3 SRAAFAWEDPFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQA 62 Query: 104 GVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQ 162 G+LG T+ + YG A S VAYGL+ARE+ER+DSGYRS MSVQSSLVM+PIYAYGS+EQR+ Sbjct: 63 GLLGVTLPEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRK 122 Query: 163 KYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLF 222 KYLP L GEL+GCFGLTEP++GSDP+ M+TRA + Y L+G+K WI+NSP+AD+F Sbjct: 123 KYLPGLVSGELIGCFGLTEPDAGSDPAGMKTRAE--KIDGGYRLSGSKMWISNSPIADVF 180 Query: 223 VVWAR--CEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA 280 VVWA+ D IRGF+LEKGM+GLSAP+I GK SLRAS TG I+MDGVEV E+ +LP Sbjct: 181 VVWAKSAAHDNAIRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAILPNV 240 Query: 281 SSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADML 340 S L GPFGCLN ARYGI+WGVLGA+E C ARQY LDR QF PLA QL QKKLADM Sbjct: 241 SGLKGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQ 300 Query: 341 TEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHV 400 TEI LG+ A L++GRL D+ K APEM+S++KRNNCGKALDIARQARDM GGNGI EYHV Sbjct: 301 TEIALGIQASLRVGRLFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHV 360 Query: 401 IRHAMNLEAVNTYEGTHDIHALILGRAITGIQAF 434 +RHA NLE VNTYEGTHD+HALILGRA TGIQAF Sbjct: 361 MRHAQNLETVNTYEGTHDVHALILGRAQTGIQAF 394 >3GNC-A nrPDB Length = 399 Score = 516 bits (1329), Expect = e-147, Method: Compositional matrix adjust. Identities = 258/391 (65%), Positives = 302/391 (77%), Gaps = 6/391 (1%) Query: 48 FDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG 107 F W DPL+L++QL DE ++RD Y Q +L PR+ A R+E I EMGE+G+LG Sbjct: 10 FHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLG 69 Query: 108 PTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLP 166 PTI + YG G+ V+YGL+ARE+ERVDSGYRS MSVQSSLVM PI+ +GS+ Q++KYLP Sbjct: 70 PTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLP 129 Query: 167 QLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWA 226 +LA GE +GCFGLTEPN GSDP SM TRA Y+L+G+K WITNSP+AD+FVVWA Sbjct: 130 KLATGEWIGCFGLTEPNHGSDPGSMVTRA--RKVPGGYSLSGSKMWITNSPIADVFVVWA 187 Query: 227 RC-EDGC--IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSL 283 + EDG IRGF+LEKG +GLSAP I GK LRAS TG I++D VPEEN+LP L Sbjct: 188 KLDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHVKGL 247 Query: 284 GGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEI 343 GPF CLN+ARYGIAWG LGA+E C H ARQY LDR QFG PLA NQLIQKKLADM TEI Sbjct: 248 RGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEI 307 Query: 344 TLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRH 403 TLGL L+LGR+KD+ AA E+ S++KRN+CGKALDIAR ARDMLGGNGISDE+ V RH Sbjct: 308 TLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARH 367 Query: 404 AMNLEAVNTYEGTHDIHALILGRAITGIQAF 434 +NLE VNTYEGTHDIHALILGRA TGIQAF Sbjct: 368 LVNLEVVNTYEGTHDIHALILGRAQTGIQAF 398 >3SF6-A nrPDB Length = 403 Score = 377 bits (969), Expect = e-105, Method: Compositional matrix adjust. Identities = 202/403 (50%), Positives = 264/403 (65%), Gaps = 4/403 (0%) Query: 33 GGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRIL-LANRNEV 91 G T S +A+ D + + L+ +E IRDT R+ Q R+ P I E+ Sbjct: 3 GSMTNSAVAQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGEL 62 Query: 92 FHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHP 151 RE+ E+GELG+LG +KGYGCAG+S+VAYGL ELE DSG RS +SVQ SL M+ Sbjct: 63 PARELAVELGELGLLGMHLKGYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYA 122 Query: 152 IYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKT 211 I+A+GS+EQ+ ++LP +A G +GCFGLTEP+ GSDP+ M TRA S + L GTK Sbjct: 123 IHAFGSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRA--TRSGDDWILTGTKM 180 Query: 212 WITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEV 271 WITN +AD+ VVWAR ++G IRGF++ G +A I+ K SLRAS T +++DGV + Sbjct: 181 WITNGSVADVAVVWARTDEG-IRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRL 239 Query: 272 PEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQL 331 P+ LPGA+SLG P CLN AR+GI +G LGA+ CL TA YA R QF P+ QL Sbjct: 240 PDSARLPGATSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQL 299 Query: 332 IQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGG 391 Q+KLADM E G L LGR KD + APE VSL K NN +A++IAR AR +LG Sbjct: 300 TQQKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLGKLNNVREAIEIARTARTVLGA 359 Query: 392 NGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAF 434 +GI+ EY V+RHA NLE+V TYEGT ++H LI+G+A+TG+ AF Sbjct: 360 SGITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQALTGVGAF 402 >2EBA-A nrPDB Length = 385 Score = 374 bits (960), Expect = e-104, Method: Compositional matrix adjust. Identities = 201/385 (52%), Positives = 253/385 (65%), Gaps = 4/385 (1%) Query: 52 DPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK 111 D LE+ LT +E ++ R + ++ +P I VF +I ELG LGPT+ Sbjct: 3 DFYALEDLLTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLP 62 Query: 112 G-YGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAK 170 YG AGVSS AYGL+ ELERVDSG RS +SVQSSLVM+PIYAYGSEEQ++++LP+LA+ Sbjct: 63 PEYGGAGVSSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLAR 122 Query: 171 GELLGCFGLTEPNSGSDP-SSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE 229 GE++GCFGLTEP+ GSDP +M+TRA ++ LNGTK WITN +A L V+WA+ E Sbjct: 123 GEMVGCFGLTEPDGGSDPYGNMKTRA--RREGDTWVLNGTKMWITNGNLAHLAVIWAKDE 180 Query: 230 DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC 289 G + GFL+ G A ++ K SLRAS T ++++ V VPE LP A L P C Sbjct: 181 GGEVLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRLPKALGLKAPLSC 240 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L AR+GIAWG +GA E A +A R FG PLA+ QL+Q KLA+ML T GL Sbjct: 241 LTQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGLLL 300 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 +L RLKD+ K P VSL KR N KAL AR ARD+LGG+GI+ EYH IRH +NLE Sbjct: 301 AWRLARLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLET 360 Query: 410 VNTYEGTHDIHALILGRAITGIQAF 434 V TYEGTHD+H L+LGR ITG+ AF Sbjct: 361 VYTYEGTHDVHTLVLGREITGLNAF 385 >3SWO-A nrPDB Length = 399 Score = 341 bits (875), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 180/375 (48%), Positives = 238/375 (63%), Gaps = 3/375 (0%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVS 119 L DE I T R + RL P + + E+ E G LGVLG ++GYGCAG + Sbjct: 26 LDQDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHLQGYGCAGTN 85 Query: 120 SVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGL 179 +V+YGL ELE DSG+RS +SVQ SL M IY YGSEEQ+ ++LP+LA G+ +GCFGL Sbjct: 86 AVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGL 145 Query: 180 TEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLE 239 TEP+ GS+P+ M TRA + S+ + LNGTK WITN +AD+ VWA+ +DG IRGFL+ Sbjct: 146 TEPDFGSNPAGMRTRARRDGSD--WILNGTKMWITNGNLADVATVWAQTDDG-IRGFLVP 202 Query: 240 KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAW 299 G +A I K SLRAS T +++D V +P LP A L P CLN AR+GI + Sbjct: 203 TDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQLPLAEGLSAPLSCLNEARFGIVF 262 Query: 300 GVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQ 359 G LGA+ L T Y R F PL+ QL Q+KLA+M E+ G+ + LGR+KD Sbjct: 263 GALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLAIHLGRIKDA 322 Query: 360 DKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDI 419 + PE +SL K NN +A+ IAR+ R +LGG+GI+ EY +RHA NLE+V TYEGT ++ Sbjct: 323 EGVRPEQISLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEM 382 Query: 420 HALILGRAITGIQAF 434 H L +G+A+TG AF Sbjct: 383 HLLSIGKALTGKAAF 397 >2IX5-A nrPDB Length = 436 Score = 231 bits (589), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 140/380 (36%), Positives = 202/380 (53%), Gaps = 3/380 (0%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGC 115 + LT +E IR R ++ + P + F I ++G +GV G +IKGYGC Sbjct: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGC 110 Query: 116 AGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLG 175 G+S A + E+ RVD+ + + V SSL M I GSE Q++KYLP LA+ + Sbjct: 111 PGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVA 170 Query: 176 CFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWAR-CEDGCIR 234 C+ LTEP++GSD S + T A + +NG K WI NS ADL +++AR I Sbjct: 171 CWALTEPDNGSDASGLGTTA--TKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQIN 228 Query: 235 GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNAR 294 GF+++K GL A +I K LR G I++ V VP+E+ LPG +S L +R Sbjct: 229 GFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSR 288 Query: 295 YGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLG 354 +AW +G S +Y +R QFG PLA QL Q+KL ML + +L Sbjct: 289 VMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC 348 Query: 355 RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 414 +L + + P SL K KA + A R++LGGNGI ++ V + +LE + TYE Sbjct: 349 KLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYE 408 Query: 415 GTHDIHALILGRAITGIQAF 434 GT+DI+ L+ GR +TGI +F Sbjct: 409 GTYDINTLVTGREVTGIASF 428 >4L1F-A nrPDB Length = 383 Score = 207 bits (528), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 126/380 (33%), Positives = 201/380 (52%), Gaps = 10/380 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYG 114 ++ LT D+ +I+D + ++ L P + ++ ++ R++I +MGE G G + YG Sbjct: 1 MDFNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 G+ ++Y L EL +VD G +S SL PIY +G+EEQ+QKYL +A+G + Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG--- 231 G FGLTEP++G+D S+ +T A Y LNG+K +ITN AD +VV+A + Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVLKGDK--YILNGSKIFITNGKEADTYVVFAMTDKSQGV 178 Query: 232 -CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG-- 288 I F+LEKGM G +I+ K S T +I + EVP+EN+L G G Sbjct: 179 HGISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLL-GKEGEGFKIAME 237 Query: 289 CLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLH 348 L+ R G+A LG +E L A +Y+ +R QFG +++ Q +Q +ADM T+I + Sbjct: 238 TLDGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARY 297 Query: 349 ACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLE 408 LK++ K E ++ K A+++ A + GG G + +Y R+ N + Sbjct: 298 LVYHAAMLKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAK 357 Query: 409 AVNTYEGTHDIHALILGRAI 428 YEGT+ + ++ RA+ Sbjct: 358 ITQIYEGTNQVMRIVTSRAL 377 >5LNX-A nrPDB Length = 379 Score = 205 bits (521), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 128/378 (33%), Positives = 195/378 (51%), Gaps = 8/378 (2%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTIKGYGCAG 117 +T +++++R R + ++ + P + + + F ++I +MG+ G++G P + YG AG Sbjct: 2 HVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAG 61 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 V+Y L E+ R+ + +SV +S+ +PI +G+EEQ+ KY+P LA G+ LG F Sbjct: 62 ADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAF 121 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC--EDG--CI 233 LTEP+SGSD S+ T A N Y LNG+K +ITN AD+++ +A + G I Sbjct: 122 ALTEPHSGSDAGSLRTTA--IKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGI 179 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL-PGASSLGGPFGCLNN 292 F++EK G + + + K L S T +I D EVPE N+L LN Sbjct: 180 SAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNV 239 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R GIA LG +E L A YA R+QFG P+A NQ I KLADM T H Sbjct: 240 GRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYH 299 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L ++ + S+ K+ A+ A A + GG G +Y V R + + Sbjct: 300 AADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQI 359 Query: 413 YEGTHDIHALILGRAITG 430 YEGT++I LI+ + + G Sbjct: 360 YEGTNEIQRLIISKYLLG 377 >5OL2-C nrPDB Length = 378 Score = 190 bits (483), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 120/366 (32%), Positives = 189/366 (51%), Gaps = 10/366 (2%) Query: 66 LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTIKGYGCAGVSSVAYG 124 ++++ + ++ + + P + E F E + +M + G++G P K YG G +V Y Sbjct: 10 MLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGDTVGYI 69 Query: 125 LLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNS 184 + EL RV +S +SL PIY YG+EEQ+QK+L LA GE LG FGLTEPN+ Sbjct: 70 MAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPNA 129 Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCIRGFLLEK 240 G+D S +T A + Y LNG+K +ITN+ D++VV A + + I F++EK Sbjct: 130 GTDASGQQTTAVLDGDE--YILNGSKIFITNAIAGDIYVVMAMTDKSKGNKGISAFIVEK 187 Query: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNNARYGIA 298 G G S + K +R SAT +I + +P+EN+L G G L+ R GIA Sbjct: 188 GTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLL-GKEGQGFKIAMSTLDGGRIGIA 246 Query: 299 WGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD 358 LG ++ L +Y +R+QFG PL++ Q Q +LADM ++ H Q KD Sbjct: 247 AQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQAAINKD 306 Query: 359 QDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHD 418 K ++ K A+++ +A + GG G + +Y V R + + YEGT + Sbjct: 307 LGKPYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIYEGTSE 366 Query: 419 IHALIL 424 + +++ Sbjct: 367 VQRMVI 372 >1BUC-A nrPDB Length = 383 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 119/365 (32%), Positives = 193/365 (52%), Gaps = 12/365 (3%) Query: 74 YCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK----GYGCAGVSSVAYGLLARE 129 + +++L P + + ++ +E+I E+ LG+ G + G G G ++Y L E Sbjct: 19 FGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYGGSGDDGGDVLSYILAVEE 78 Query: 130 LERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPS 189 L + D+G +S SL +PI+ +G+E Q++K+L L +G LG FGLTEPN+G+D S Sbjct: 79 LAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGTKLGAFGLTEPNAGTDAS 138 Query: 190 SMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCIRGFLLEKGMRGL 245 +T A N + +YTLNG+K +ITN AD+++V+A + + I F+LE G G Sbjct: 139 GQQTIATKND-DGTYTLNGSKIFITNGGAADIYIVFAMTDKSKGNHGITAFILEDGTPGF 197 Query: 246 SAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNNARYGIAWGVLG 303 + + + K + S T ++ V+VP EN+L G G L+ R G+A LG Sbjct: 198 TYGKKEDKMGIHTSQTMELVFQDVKVPAENML-GEEGKGFKIAMMTLDGGRIGVAAQALG 256 Query: 304 ASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAA 363 +E L A +Y+ R+QFG PL + Q I KLADM +I + + K + K Sbjct: 257 IAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAARNLVYKAACKKQEGKPF 316 Query: 364 PEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALI 423 ++ KR A+ + +A + GG G S+EY V RH + + YEGT+++ ++ Sbjct: 317 TVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDAKITQIYEGTNEVQLMV 376 Query: 424 LGRAI 428 G A+ Sbjct: 377 TGGAL 381 >2DVL-A nrPDB Length = 372 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 129/371 (34%), Positives = 191/371 (51%), Gaps = 5/371 (1%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGV 118 LT ++ L+ D R +E L P +R + + + ELG+LG T + +G G+ Sbjct: 3 LTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 SV + L EL D +SV S L + + +GSE Q+++YL LA+GE +G F Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLL 238 LTEP +GSD S+ RA + LNG K+WIT++ A L+VV AR E G I FL+ Sbjct: 123 LTEPQAGSDAKSL--RAEARRVKGGFVLNGVKSWITSAGHAHLYVVMARTEKG-ISAFLV 179 Query: 239 EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL-PGASSLGGPFGCLNNARYGI 297 EKG GLS R + K L A+ T + ++ V VPEEN+L L L++ R G+ Sbjct: 180 EKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGLDSGRVGV 239 Query: 298 AWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLK 357 A +G + A+ YA +R QFG L +Q I K+ADM +I L+ R K Sbjct: 240 AAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLEAARKK 299 Query: 358 DQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTH 417 D+ + S K A+++ R+A +LGG G +Y V R+ + + YEGT Sbjct: 300 DRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEIYEGTS 359 Query: 418 DIHALILGRAI 428 +I L++ R + Sbjct: 360 EIQRLVIAREL 370 >3OWA-A nrPDB Length = 597 Score = 181 bits (458), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 125/397 (31%), Positives = 197/397 (49%), Gaps = 27/397 (6%) Query: 52 DPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREI--ISEMGELGVLGPT 109 D + E +++ +I T + ++P + ++E F R + + E GELG+LG Sbjct: 25 DQVFTPEDFSSEHKMIAKTTEDFIVNEVLPELEYLEQHE-FDRSVRLLKEAGELGLLGAD 83 Query: 110 I-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQL 168 + + YG G+ V+ L+A + R G+ + PI +G+EEQ++KYLP L Sbjct: 84 VPEEYGGIGLDKVSSALIAEKFSRA-GGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLL 142 Query: 169 AKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC 228 A GE L + LTEP SGSD +T A N+ Y LNG K WITNS AD+F+V+A+ Sbjct: 143 ATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYAKI 202 Query: 229 EDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGG--P 286 + F++EK G+S + K ++ S+T +I++ VP+EN+L G G Sbjct: 203 DGEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLL-GEIGKGHIIA 261 Query: 287 FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEI--- 343 F LN RY + G +G+++ + + QYA R QF P+AR LIQ+KLA+M + Sbjct: 262 FNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAA 321 Query: 344 ------TLGLH----ACLQLGRLKDQDKAAPEMVSL-----LKRNNCGKALD-IARQARD 387 T+GL + L +KD A + L + + LD + Sbjct: 322 ESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQ 381 Query: 388 MLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALIL 424 + GG G EY + R + +EGT++I+ LI+ Sbjct: 382 IHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIV 418 >2Z1Q-A nrPDB Length = 577 Score = 178 bits (452), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 124/377 (32%), Positives = 195/377 (51%), Gaps = 22/377 (5%) Query: 67 IRDTFRTYCQERLMPRILLANRNEV-FHREIISEMGELGVLGPTI-KGYGCAGVSSVAYG 124 I T RT+ + ++P + E+ + ++ + GELG+L + + YG + V Sbjct: 35 IARTTRTFVEREVLPLLERMEHGELELNVPLMRKAGELGLLAIDVPEEYGGLDLPKVIST 94 Query: 125 LLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNS 184 ++A EL G+ +S+ P+ +G+EEQ++KYLP+LA GE + + LTEP S Sbjct: 95 VVAEELSG-SGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAAYCLTEPGS 153 Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRG 244 GSD + +TRA + K Y LNG K WI+N+ A LF V+A+ + FL+E+ G Sbjct: 154 GSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAKVDGEHFTAFLVERDTPG 213 Query: 245 LSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGP--FGCLNNARYGIAWGVL 302 LS + K ++AS+T +I++ V+VP ENVL G G F LN RY + G + Sbjct: 214 LSFGPEEKKMGIKASSTRQVILEDVKVPVENVL-GEIGKGHKIAFNVLNVGRYKLGAGAV 272 Query: 303 GASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQ--- 359 G ++ L + QYA R+QFG P+ R LIQ+KL +M + I A + L D+ Sbjct: 273 GGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAESAVYRTVGLIDEALL 332 Query: 360 DKAAPEMV-----------SLLKRNNCGKALD-IARQARDMLGGNGISDEYHVIRHAMNL 407 K PE V S++K + LD + + + GG G S EY + R + Sbjct: 333 GKKGPEAVMAGIEEYAVEASIIKVLGS-EVLDYVVDEGVQIHGGYGYSQEYPIERAYRDA 391 Query: 408 EAVNTYEGTHDIHALIL 424 +EGT++I+ L++ Sbjct: 392 RINRIFEGTNEINRLLI 408 >2VIG-A nrPDB Length = 391 Score = 177 bits (449), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 118/371 (31%), Positives = 187/371 (50%), Gaps = 11/371 (2%) Query: 62 TDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSS 120 T ++L++ T R + ++ L P ++ +F + +MG LG+L + + G AG+ Sbjct: 9 THQMLLQ-TCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDY 67 Query: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180 +AY + E+ R + MSV +SL + PI +GS+EQ+Q ++ G+ +GCF L+ Sbjct: 68 LAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALS 127 Query: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCIRGF 236 EP +GSD + T A + S+ LNGTK WITN+ A VV+A + + I F Sbjct: 128 EPGNGSDAGAASTTAR--AEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSISAF 185 Query: 237 LLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNNAR 294 L+ GL+ + + K +R S+T +I + +P++++L G +G L+ R Sbjct: 186 LVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSIL-GEPGMGFKIAMQTLDMGR 244 Query: 295 YGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLG 354 GIA LG ++ L A YA +RM FG PL + Q+IQ KLADM + + Sbjct: 245 IGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAA 304 Query: 355 RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 414 LKD K + ++ K A I+ QA +LGG G E RH + YE Sbjct: 305 MLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYE 364 Query: 415 GTHDIHALILG 425 GT +I L++ Sbjct: 365 GTSEIQRLVIA 375 >1JQI-A nrPDB Length = 388 Score = 177 bits (449), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 118/367 (32%), Positives = 184/367 (50%), Gaps = 10/367 (2%) Query: 66 LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYG 124 ++R T R + ++ L+P ++ +F + +MGELG+L + + AG+ +AY Sbjct: 16 MLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAGLDYLAYS 75 Query: 125 LLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNS 184 + E+ R + MSV +SL + PI +GS +Q+Q+++ G+ +GCF L+EP + Sbjct: 76 IALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFALSEPGN 135 Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCIRGFLLEK 240 GSD + T A S+ LNGTK WITNS A VV+A + + I FL+ Sbjct: 136 GSDAGAASTTAR--EEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPM 193 Query: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNNARYGIA 298 GL+ + + K +RAS+T +I + +P+EN+L G +G L+ R GIA Sbjct: 194 PTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLL-GEPGMGFKIAMQTLDMGRIGIA 252 Query: 299 WGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD 358 LG ++ L A +YA +R FG PL + Q IQ KLADM + + LKD Sbjct: 253 SQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKD 312 Query: 359 QDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHD 418 K + ++ K A I+ QA +LGG G E R+ + YEGT + Sbjct: 313 NKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSE 372 Query: 419 IHALILG 425 I L++ Sbjct: 373 IQRLVIA 379 >4KTO-A nrPDB Length = 410 Score = 176 bits (445), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 119/368 (32%), Positives = 183/368 (49%), Gaps = 8/368 (2%) Query: 67 IRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYGL 125 +R + R + ER+ P A+R+ F + EMGELG+LG T + +G AG+ +A+ + Sbjct: 40 LRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAHGGAGLGYLAHCV 99 Query: 126 LARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSG 185 E+ R + + S+L ++ I G Q+ +YLP+L GE +G ++EP +G Sbjct: 100 AMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEHVGALAMSEPGAG 159 Query: 186 SDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEKG 241 SD SM+ +A + Y LNG+K WITN P AD+ VV+A+ + I FL+EK Sbjct: 160 SDVVSMKLKA--DKRGDRYVLNGSKMWITNGPDADVLVVYAKTDPAAGPRGITAFLVEKA 217 Query: 242 MRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGCLNNARYGIAWG 300 G SA + K +R S T +I EVPEENVL G + L+ R ++ G Sbjct: 218 FPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLMSGLDYERVVLSAG 277 Query: 301 VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD 360 LG CL Y +R QFG P+ QL+Q KLADM + + D+ Sbjct: 278 PLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAARAYVYAVAAACDRG 337 Query: 361 KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420 + A + + KA +A +A LGGNG +++Y R + + GT +I Sbjct: 338 ETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAKLYEIGAGTSEIR 397 Query: 421 ALILGRAI 428 +++GR + Sbjct: 398 RMLIGREL 405 >4O5M-A nrPDB Length = 390 Score = 175 bits (444), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 121/371 (32%), Positives = 179/371 (48%), Gaps = 14/371 (3%) Query: 67 IRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYGL 125 +RDT R + + R+ P +RN F + E GELGVLG T + YG AG+ +A+ + Sbjct: 20 LRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYGGAGMGYLAHCI 79 Query: 126 LARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSG 185 E+ R + + S+L ++ I GS EQR KYLP+L GE +G ++EP +G Sbjct: 80 AMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHVGALAMSEPGAG 139 Query: 186 SDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEKG 241 SD SM+ A Y LNG K WITN P AD+ VV+A+ + I F++EKG Sbjct: 140 SDVVSMKLAAE--KRGDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGPRGISAFIIEKG 197 Query: 242 MRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL----PGASSLGGPFGCLNNARYGI 297 +G S + K +R S T ++ + EVP EN+L G + L L+ R + Sbjct: 198 FKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVL---MSGLDYERVVL 254 Query: 298 AWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLK 357 A G LG CL Y +R QF P+ QL+Q KLADM + Sbjct: 255 AGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAYVYAVAAAC 314 Query: 358 DQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTH 417 D+ + + + + A +A QA LGGNG ++Y R + + GT Sbjct: 315 DRGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKLYEIGAGTS 374 Query: 418 DIHALILGRAI 428 +I +++GR + Sbjct: 375 EIRRMLIGREL 385 >4U83-A nrPDB Length = 382 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 116/376 (30%), Positives = 183/376 (48%), Gaps = 10/376 (2%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGV 118 LT + IR+ R + QERL P +R F R ++EMG LG LG + +G + + Sbjct: 10 LTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGSDL 69 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 VAY L E+ D + +SV SS+ PI +G+E+Q++++LP++A GE +G F Sbjct: 70 DMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFA 129 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IR 234 LTEP +GSD S+++TRA + + Y ++G+K +IT+ ++ +V+A + I Sbjct: 130 LTEPQAGSDASALKTRARLDGDH--YVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGIS 187 Query: 235 GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLN--N 292 F++ G ++ K +S T + + VP EN L GA G N Sbjct: 188 AFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRL-GAEGEGYKIALANLEG 246 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R GIA +G + AR YA +R+ FG P+ +Q + +LADM T I L Sbjct: 247 GRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLH 306 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L++ K S+ K A + A + GG G +Y V R ++ Sbjct: 307 AAALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQI 366 Query: 413 YEGTHDIHALILGRAI 428 YEGT D+ L++ R + Sbjct: 367 YEGTSDVQRLVIARGL 382 >4N5F-A nrPDB Length = 385 Score = 169 bits (428), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 113/377 (29%), Positives = 182/377 (48%), Gaps = 8/377 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYG 114 ++E T D+ +IRD R + E L P + + I++++GELG+LG + + G Sbjct: 9 MDELYTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELG 68 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 + VAY L E+ D+ + MSV +S+ PI +G+ Q+ ++L +A G ++ Sbjct: 69 GSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVI 128 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC-- 232 G F LTEP++GS+ +++ TRA + + LNG K ++TN A + +V+A + Sbjct: 129 GAFCLTEPHAGSEANNLRTRAELR--DGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEAGK 186 Query: 233 --IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGC 289 I FL+ G + + K +RAS T I + +PE+N+L L Sbjct: 187 RGISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALSN 246 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L R GIA LG + AR+YA +R+QFG P+A +Q IQ+KLADM +I Sbjct: 247 LEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLL 306 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 +L+ S K A + A + GG G +Y V RH + Sbjct: 307 VHHAAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARI 366 Query: 410 VNTYEGTHDIHALILGR 426 YEGT ++ +++ R Sbjct: 367 TQIYEGTSEVQRMVIAR 383 >2JIF-A nrPDB Length = 404 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 112/388 (28%), Positives = 193/388 (49%), Gaps = 14/388 (3%) Query: 48 FDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG 107 F PL + T +E++I+ + + + QE++ P + + N + +I + + G++G Sbjct: 20 FQSMAPL---QTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMG 76 Query: 108 PTIK-GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLP 166 + YG G S ++ L+ EL +VD+ +Q++L+ I +G+EEQ+ YLP Sbjct: 77 IEVDPEYGGTGASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLP 136 Query: 167 QLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWA 226 QL E +G F L+E +GSD +++TRA + Y LNG+K WI+++ A LF+V A Sbjct: 137 QLTT-EKVGSFCLSEAGAGSDSFALKTRA--DKEGDYYVLNGSKMWISSAEHAGLFLVMA 193 Query: 227 RCEDGC----IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASS 282 + I FL+++ GL + + K LRAS+T + + V+VPE N+L G Sbjct: 194 NVDPTIGYKGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANIL-GQIG 252 Query: 283 LGGPF--GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADML 340 G + G LN R GIA +LG ++ C Y +R+QFG L Q +Q ++A + Sbjct: 253 HGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVA 312 Query: 341 TEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHV 400 T++ RL + K + S+ K A + + +GG G + +Y V Sbjct: 313 TQLEAARLLTYNAARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPV 372 Query: 401 IRHAMNLEAVNTYEGTHDIHALILGRAI 428 ++ + + YEG +I + + I Sbjct: 373 EKYFRDAKIGTIYEGASNIQLNTIAKHI 400 >4M9A-A nrPDB Length = 385 Score = 158 bits (399), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 115/379 (30%), Positives = 186/379 (49%), Gaps = 8/379 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKG-YG 114 +++ T D+ +I D R +C E L P +R E++++MGELG LG + +G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 + VAY L E+ + + +SV +S+ P+ YG+ EQ++++L LA G+ + Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE-DGCI 233 G F LTEP++GS+ ++ TRA + + LNG+K ++TN A L +V+A + D Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELR--DGKWILNGSKQFVTNGARAGLAIVFAMTDPDEGK 186 Query: 234 RG---FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL-PGASSLGGPFGC 289 RG F++ G + + K +RAS T I ++ +P+EN+L L Sbjct: 187 RGLSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSN 246 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L R GIA G + AR+YA +R+QFG P+A +Q I +KLA+M T+I Sbjct: 247 LEGGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLL 306 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 RL+ S K A + A + GG G +Y V RH + Sbjct: 307 THHAARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARI 366 Query: 410 VNTYEGTHDIHALILGRAI 428 YEGT ++ +++ R + Sbjct: 367 TQIYEGTSEVQRMVIARQL 385 >3MPI-A nrPDB Length = 397 Score = 157 bits (398), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 112/389 (28%), Positives = 194/389 (49%), Gaps = 16/389 (4%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRI-LLANRNEVFHREIISEMGELGVLGPTI-KGY 113 ++ L+ + +++ R + ++++P N N + E + MGELG G I + Y Sbjct: 1 MDFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEY 60 Query: 114 GCAGVSS--VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 171 G G+ +A ++ E+ R S R ++++ + I YGSE ++KY+P+L+ Sbjct: 61 GGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSA 120 Query: 172 ELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG 231 E LG FG+TEP++GSD +M + A + LNG+KTWI+N+ AD+ + +A + Sbjct: 121 EFLGGFGITEPDAGSDVMAMSSTAE--DKGDHWLLNGSKTWISNAAQADVLIYYAYTDKA 178 Query: 232 C----IRGFLLE-KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL--PGASSLG 284 + F++E + G+ ++ K AS TG + +D V+VP+EN+L PG + Sbjct: 179 AGSRGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGAR- 236 Query: 285 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 344 FG LN+ R A G +G ++ CL A +Y +R QFG P+ Q+ Q +A M E+ Sbjct: 237 IVFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVE 296 Query: 345 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALD-IARQARDMLGGNGISDEYHVIRH 403 + KD+ + + + + G+A+ A A +LG G S EY V R Sbjct: 297 AARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARF 356 Query: 404 AMNLEAVNTYEGTHDIHALILGRAITGIQ 432 + EG+ +I +I+ G++ Sbjct: 357 YRDAPTYYMVEGSANICKMIIALDQLGVR 385 >1IVH-A nrPDB Length = 394 Score = 157 bits (397), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 113/385 (29%), Positives = 184/385 (47%), Gaps = 22/385 (5%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFH--REIISEMGELGVLGPTIK-GYGCA 116 L+ ++ +R T + QE L P+ +R+ F RE ++G LGVLG T YG + Sbjct: 13 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGS 72 Query: 117 GVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGC 176 G+ + + L+ E+ R + S+L ++ + G+E Q++KYLP+L GE +G Sbjct: 73 GLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGA 132 Query: 177 FGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC---- 232 ++EPN+GSD SM+ +A ++ Y LNG K WITN P AD+ +V+A+ + Sbjct: 133 LAMSEPNAGSDVVSMKLKAEKKGNH--YILNGNKFWITNGPDADVLIVYAKTDLAAVPAS 190 Query: 233 --IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL----PGASSLGGP 286 I F++EKGM G S + K +R S T +I + ++P N+L G L Sbjct: 191 RGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVL--- 247 Query: 287 FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG 346 L+ R +A G LG + L Y R FG + QL+Q K+ADM T + Sbjct: 248 MSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMAC 307 Query: 347 LHACLQLGRLKDQDKAAPEMVS--LLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 404 + + D+ + + +L C A +A GGNG +++ + R Sbjct: 308 RQYVYNVAKACDEGHCTAKDCAGVILYSAEC--ATQVALDGIQCFGGNGYINDFPMGRFL 365 Query: 405 MNLEAVNTYEGTHDIHALILGRAIT 429 + + GT ++ L++GRA Sbjct: 366 RDAKLYEIGAGTSEVRRLVIGRAFN 390 >1UKW-A nrPDB Length = 379 Score = 157 bits (396), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 116/376 (30%), Positives = 183/376 (48%), Gaps = 11/376 (2%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGV 118 LT ++ ++ R + +E ++P + E +I ++ E+G+L I + YG G+ Sbjct: 5 LTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGL 64 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 + ++ EL G + + + S L + P+ G+EEQ++++L L + L F Sbjct: 65 KMLDEVIVGEELAYACMGIYT-IPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFA 123 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IR 234 L+EP +GSD ++++TRA + Y LNGTK WI+N A+ VV+A + Sbjct: 124 LSEPGNGSDAAALKTRAIRQGDH--YVLNGTKMWISNGGEAEWVVVFATVNPELRHKGVV 181 Query: 235 GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNN 292 ++E+G G A +I GK RAS T ++ + V+VP EN L G G LN Sbjct: 182 ALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRL-GEEGEGFKIAMQTLNK 240 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R +A G +G + L AR+YA +R FG P+A Q IQ KL DML I Sbjct: 241 TRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYY 300 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L DQ ++ K A + A QA + GG G E+ V + +++ Sbjct: 301 AAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQI 360 Query: 413 YEGTHDIHALILGRAI 428 YEGT++I LI+ R I Sbjct: 361 YEGTNEIQRLIIARHI 376 >3B96-A nrPDB Length = 587 Score = 151 bits (381), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 111/347 (31%), Positives = 171/347 (49%), Gaps = 29/347 (8%) Query: 97 ISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYG 156 + E+G G+ P+ G G+ + Y L + D G + S+ I +G Sbjct: 68 LKELGAFGLQVPS--ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFG 125 Query: 157 SEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS 216 ++ Q++KYLP+LA GE + F LTEP+SGSD +S+ T A + K YTLNG+K WI+N Sbjct: 126 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 185 Query: 217 PMADLFVVWARC-----EDGCIR----GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMD 267 +AD+F V+A+ G ++ F++E+G G++ + K ++AS T + D Sbjct: 186 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 245 Query: 268 GVEVPEENVLPGASSLGGPFGC----LNNARYGIAWGVLGASEFCLHTARQYALDRMQFG 323 GV VP ENVL +G F LNN R+G+A + G + A +A +R QFG Sbjct: 246 GVRVPSENVL---GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFG 302 Query: 324 VPLARNQLIQKKLADM-----LTE-ITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGK 377 + LIQ+KLA M +TE + + A + G Q +AA + K Sbjct: 303 EKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAA-----ISKIFGSEA 357 Query: 378 ALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALIL 424 A + + ++GG G E V R +L +EGT+DI L + Sbjct: 358 AWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 404 >6FAH-C nrPDB Length = 379 Score = 144 bits (364), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 114/370 (30%), Positives = 173/370 (46%), Gaps = 17/370 (4%) Query: 66 LIRDTFRTYCQERLMPRILLANRNEV-----FHREIISEMGELGVLGPTI-KGYGCAGVS 119 +IR R + ++ L IL +EV F +EI+ +M + G G I K G +G Sbjct: 9 MIRKLARDFAEKELTTEIL----DEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGD 64 Query: 120 SVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGL 179 ++Y + E RV +S +SL P+ G+EEQ +KYL + G+ F L Sbjct: 65 HMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFAL 124 Query: 180 TEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE--DGC--IRG 235 TEP +GSD M T A Y LNG KT+IT +P+ D V++A+ + G I Sbjct: 125 TEPGAGSDAGGMSTTAV--DMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISA 182 Query: 236 FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASS-LGGPFGCLNNAR 294 F+++ G+S + + K L AT IIM+ V+VP+EN L + L+ R Sbjct: 183 FIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGR 242 Query: 295 YGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLG 354 G+A +G ++ L A +YA +R QFG +A Q I +ADM T++ Sbjct: 243 LGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAA 302 Query: 355 RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 414 L D K A + S+ K +I +A + GG G EY V R + YE Sbjct: 303 SLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYE 362 Query: 415 GTHDIHALIL 424 GT + +++ Sbjct: 363 GTSQVQQMVI 372 >2A1T-A nrPDB Length = 421 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 105/377 (27%), Positives = 181/377 (48%), Gaps = 12/377 (3%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 + T + + T R + +E ++P ++ + +I ELG++ I + G G Sbjct: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 + + L++ EL +G ++A+ +SL PI G+++Q++KYL ++ + L+ + Sbjct: 100 LGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE-------D 230 +TEP +GSD + ++T+A Y +NG K WITN A+ + + AR + + Sbjct: 159 CVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 Query: 231 GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGC 289 GF++E G+ R + R S T I+ + V+VP+ENVL G + G Sbjct: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 + R +A G +G ++ L A +YAL+R FG L +Q I LA+M ++ L + Sbjct: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 + D + S+ K A +A A +LGGNG + EY V + + + Sbjct: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 Query: 410 VNTYEGTHDIHALILGR 426 YEGT I LI+ R Sbjct: 397 YQIYEGTSQIQRLIVAR 413 >3MDE-A nrPDB Length = 385 Score = 139 bits (350), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 105/381 (27%), Positives = 180/381 (47%), Gaps = 12/381 (3%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 +LT + + T R + +E ++P +R + ++ ELG++ I + +G G Sbjct: 5 ELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFGGLG 64 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 + + L+ EL +G ++A+ ++L P+ G+ +Q++KYL ++ + L+ + Sbjct: 65 LGIIDSCLITEELAYGCTGVQTAIEA-NTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAY 123 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE-------D 230 +TEP +GSD + ++T+A Y +NG K WITN A+ + + AR + Sbjct: 124 CVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAS 181 Query: 231 GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGC 289 GF++E G+ R + R S T I+ + V VP+ENVL G + G Sbjct: 182 KAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGT 241 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 + R +A G +G ++ L A +YAL+R FG LA +Q I LADM ++ L + Sbjct: 242 FDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLS 301 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 + D + S+ K A +A A + GGNG + EY V + + + Sbjct: 302 YQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKI 361 Query: 410 VNTYEGTHDIHALILGRAITG 430 YEGT I +I+ R G Sbjct: 362 YQIYEGTAQIQRIIIAREHIG 382 >3NF4-A nrPDB Length = 387 Score = 137 bits (346), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 104/383 (27%), Positives = 181/383 (47%), Gaps = 10/383 (2%) Query: 53 PLVLEEQLTTDEI--LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PT 109 P+ ++ L + E LI T R + L P + ++E + + ++G G+L P Sbjct: 8 PMAVDRLLPSQEAAELIELT-REIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQ 66 Query: 110 IKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLA 169 + +G G Y + E+ + A+SV S L HP+ +G+EEQ++++LP + Sbjct: 67 PEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVHS-LSSHPLLVFGTEEQKKRWLPGML 125 Query: 170 KGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE 229 GE +G + L+EP +GSD +++ R ++ Y +NG+K+WIT+ AD + ++AR Sbjct: 126 SGEQIGAYSLSEPQAGSDAAAL--RCAATPTDGGYVINGSKSWITHGGKADFYTLFARTG 183 Query: 230 DGC--IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEV-PEENVLPGASSLGGP 286 +G + FL+ GLS + + K L A T D + + + L Sbjct: 184 EGSRGVSCFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIA 243 Query: 287 FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG 346 F L++ R GIA G ++ L A YA +R FG + +Q + LADM + Sbjct: 244 FSALDSGRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATA 303 Query: 347 LHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMN 406 L R +DQ + + S+ K A+ + A + GG G + +Y V R+ Sbjct: 304 RATYLDAARRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMRE 363 Query: 407 LEAVNTYEGTHDIHALILGRAIT 429 + + +EGT+ I L++ R +T Sbjct: 364 AKIMQIFEGTNQIQRLVIARGLT 386 >6ES9-A nrPDB Length = 551 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 118/388 (30%), Positives = 175/388 (45%), Gaps = 28/388 (7%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLAN-RNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 L D +IRD FR Y +ER++P + ++++ EII E+ ELGV G TI + +G G Sbjct: 167 LDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLG 226 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 +S + ++ EL R G S + +S + I G+E Q+ K+LP LA GE+L Sbjct: 227 LSKASMVVVTEELSRGYIGVGS-LGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTA 285 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC--EDGCIRG 235 TEPN+GSD S+ TRA + + + + G KTWIT++ + + AR E RG Sbjct: 286 VFTEPNTGSDLGSLRTRAVRDGED--WVVTGNKTWITHAQRTHVMTLLARTDPETTDWRG 343 Query: 236 ---FLLEK------------GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA 280 FL EK GM G + G ++ G DG + EN+L G Sbjct: 344 LSMFLAEKEPGTDDDPFPTPGMTG-GEIEVLGYRGMKEYELG---FDGFRIKGENLLGGE 399 Query: 281 SSLGGP--FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLAD 338 G +AR A +G ++ +YA+DR QFG L + KLA Sbjct: 400 PGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAM 459 Query: 339 MLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEY 398 M EI + KD + + K A A A + GGNG + EY Sbjct: 460 MAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEY 519 Query: 399 HVIRHAMNLEAVNTYEGTHDIHALILGR 426 + R + +N +EG +I A ++ R Sbjct: 520 AISRVLCDARILNIFEGAAEIQAQVIAR 547 >2PG0-A nrPDB Length = 385 Score = 134 bits (338), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 106/375 (28%), Positives = 173/375 (46%), Gaps = 19/375 (5%) Query: 66 LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYG 124 + R FR + ++ P + + R ++MGE G L P + + YG Sbjct: 16 MFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNADFAYSV 75 Query: 125 LLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNS 184 ++ ELE+V S + + + +V I +YG+EEQ+QK+LP+ GEL+ +TEP + Sbjct: 76 VINEELEKVGSSL-VGIGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIAMTEPGA 134 Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC------IRGFLL 238 GSD +++ T A Y +NG KT+ITN ADL VV + + I ++ Sbjct: 135 GSDLANISTTA--VKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPPHRGISLLVV 192 Query: 239 EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPF--GCLNNARYG 296 E+ G + R K L A T + +VP N+L G G + L R Sbjct: 193 ERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLL-GEEGKGFYYLMEKLQQERLV 251 Query: 297 IAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRL 356 +A A+E +QY R FG ++ Q +Q +LA+M TEI LG + R+ Sbjct: 252 VAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTF---VDRV 308 Query: 357 KDQDKAAPEM---VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTY 413 ++ A ++ VS+ K A +A +A + GG G +EY + R ++ Y Sbjct: 309 IEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAIY 368 Query: 414 EGTHDIHALILGRAI 428 GT+++ I+ R + Sbjct: 369 AGTNEMMKTIIARQL 383 >2CX9-A nrPDB Length = 387 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 113/376 (30%), Positives = 177/376 (47%), Gaps = 14/376 (3%) Query: 62 TDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSS 120 +E + FR + + + P +R F +++ ++ E GV G + + YG AG+S+ Sbjct: 9 AEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAYGGAGLST 68 Query: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180 + + + D ++ +SL I GSE Q++ +LP+LA GE LG +GLT Sbjct: 69 RLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLT 128 Query: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE--------DGC 232 EP SGSD ++++T+A + LNGTK +IT +A ++VV AR + Sbjct: 129 EPGSGSDAAALKTKAE--KVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSPERKHQG 186 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG--GPFGCL 290 I F + RGL R + K L AS T +I++ + VPEE +L G G L Sbjct: 187 ISAFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALL-GERGKGFYDVLRVL 245 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 + R GIA +G + L A YA R FG P+A + + KLA+ TE+ Sbjct: 246 DGGRIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARLLY 305 Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 L+ LKD + + K A+ +A +LGG G +Y V R+ + Sbjct: 306 LKAAELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWRDARLT 365 Query: 411 NTYEGTHDIHALILGR 426 EGT +I L++ R Sbjct: 366 RIGEGTSEILKLVIAR 381 >3PFD-A nrPDB Length = 393 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 95/378 (25%), Positives = 171/378 (45%), Gaps = 12/378 (3%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 QL + I +R+ R ++ + P + F E ++ + G + + YG G Sbjct: 18 QLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFSAIHVPEEYGGQG 77 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 SVA ++ E+ RVD S + + L + GSEE +++ LP +A GE + + Sbjct: 78 ADSVATCIVIEEVARVDCS-ASLIPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASY 136 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED----GCI 233 L+E +GSD +SM TRA + + + LNG+K WITN + + V A + I Sbjct: 137 ALSEREAGSDAASMRTRAVADGDD--WILNGSKCWITNGGKSTWYTVMAVTDPDKGANGI 194 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL--PGASSLGGPFGCLN 291 F++ K G + + K ++ S T + + +P + ++ PG + L+ Sbjct: 195 SAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPG-TGFKTALATLD 253 Query: 292 NARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACL 351 + R I +G ++ L A Y +R QFG P++ NQ +Q LADM +I Sbjct: 254 HTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARLMVY 313 Query: 352 QLGRLKDQDKAAPEMVSLLKRNNCGK-ALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 ++ + +S + A+++ A + GG G + ++ V R + + Sbjct: 314 SAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKIT 373 Query: 411 NTYEGTHDIHALILGRAI 428 YEGT+ I +++ RA+ Sbjct: 374 QIYEGTNQIQRVVMSRAL 391 >4IV6-A nrPDB Length = 388 Score = 124 bits (311), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 103/379 (27%), Positives = 167/379 (44%), Gaps = 13/379 (3%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGV 118 LT +E I T + ++++ P + + E+I M E+G+ G I + YG V Sbjct: 7 LTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAV 66 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 S Y +A EL R AM + +V + +G+EEQ+QKYLP++A GEL Sbjct: 67 SMPCYVQVAEELARGWMSLAGAMGGHT-VVSKLLLLFGTEEQKQKYLPRMATGELRATMA 125 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC------ 232 LTEP GSD +M T A + + Y +NG+KTWI+N+ +DL + + + Sbjct: 126 LTEPGGGSDLQAMRTVARRDGDD--YVINGSKTWISNARRSDLVALMCKTDPDAQPAHKG 183 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGP--FGCL 290 + L+EK + G R K + + + VP ++L G L Sbjct: 184 VSILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGL 242 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 R +A G + A +Y+ +R FG P+ ++Q + LADM T++ Sbjct: 243 EVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLL 302 Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 L D + + K A+ IA A + GG G S EY V R+ + + Sbjct: 303 LSAAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPLM 362 Query: 411 NTYEGTHDIHALILGRAIT 429 EGT++I ++ + + Sbjct: 363 IVGEGTNEIQRNVIAKQLV 381 >1RX0-A nrPDB Length = 393 Score = 120 bits (302), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 100/362 (27%), Positives = 172/362 (47%), Gaps = 11/362 (3%) Query: 74 YCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARELER 132 + + P + ++ E+F +++ + +LG G I+ G +G+S + ++ L Sbjct: 33 FAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALAT 92 Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSME 192 + + +S+ + + I ++G+EEQR K+ P L E + LTEP SGSD +S+ Sbjct: 93 GCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLL 151 Query: 193 TRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRG---FLLEKGMRGLSAPR 249 T A + Y LNG+K +I+ + +D++VV R +G ++EKG GLS + Sbjct: 152 TSAKKQGDH--YILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGK 209 Query: 250 IQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC--LNNARYGIAWGVLGASEF 307 + K + T +I + VP N + G+ G LN R IA LGA+ Sbjct: 210 KEKKVGWNSQPTRAVIFEDCAVPVANRI-GSEGQGFLIAVRGLNGGRINIASCSLGAAHA 268 Query: 308 CLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG-LHACLQLGRLKDQDKAAPEM 366 + R + R QFG PLA NQ +Q LADM T + L L+++ K A + Sbjct: 269 SVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVAL 328 Query: 367 VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 S+ K + I QA M GG G +Y V ++ + EG++++ +++ R Sbjct: 329 CSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISR 388 Query: 427 AI 428 ++ Sbjct: 389 SL 390 >5IDU-A nrPDB Length = 410 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 102/354 (28%), Positives = 158/354 (44%), Gaps = 38/354 (10%) Query: 94 REIISEMGELGVLGPTIKG--YGCAG--VSSVAYGLLARELERVDSGYRSAMSVQSSLVM 149 R+++ +GE G L + G YG G + + A LL L D A+++Q L Sbjct: 58 RKLVRALGEAGWLKYGVGGAQYGGHGDTIDTRAVCLLRETLANHDGLADFALAMQG-LGS 116 Query: 150 HPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGT 209 I G+ EQ+ +YLP+++KGE + F L+EP++GSD ++M +A + Y ++G Sbjct: 117 GAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQA--RAEGDCYVIDGD 174 Query: 210 KTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGV 269 KTWI+N +AD +VV+AR + G RG+SA F + A G+ I + + Sbjct: 175 KTWISNGGIADFYVVFARTGEA--------PGARGISA------FIVDADTPGLQIAERI 220 Query: 270 EVPEENVL----------PGASSLGGP-------FGCLNNARYGIAWGVLGASEFCLHTA 312 +V + L P + LG P L+ R +A LG + L Sbjct: 221 DVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRTSVAAASLGFARRALQEG 280 Query: 313 RQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKR 372 A R FG L QL Q KLA M I + L+DQ + ++ K Sbjct: 281 LARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKW 340 Query: 373 NNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 + A + A + GG G+ V R + A+ YEG ++ LI+GR Sbjct: 341 HASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGR 394 >4IRN-A nrPDB Length = 416 Score = 115 bits (287), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 97/399 (24%), Positives = 171/399 (42%), Gaps = 26/399 (6%) Query: 39 QLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIIS 98 Q+ + S +F W + +I R + Q+ L+ ++ ++ E+F+R+ Sbjct: 29 QMGRGSEFDFAW----------NSQQIQFRKKVIQFAQQSLISDLIKNDKEEIFNRDAWQ 78 Query: 99 EMGELGVLG-PTIKGYGCA--GVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAY 155 + E GV G P YG + + AY L D+G AM+ P+ + Sbjct: 79 KCSEFGVHGWPIPARYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTF 138 Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITN 215 G+EEQ++KYLP L +G + TEP +GSD S++T A + Y LNG K ++TN Sbjct: 139 GTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKDGDK--YILNGYKHYVTN 196 Query: 216 SPMADLFVVWARCEDGC----IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEV 271 +ADLF+++A + + F++EK GL + K +R + + ++ EV Sbjct: 197 GTIADLFIIFATIDPSLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEV 256 Query: 272 PEENVLPGASSLGGPFGCLNNA----RYGIAWGVLGASEFCLHTARQYALDRMQFGVPLA 327 N L G N++ R I +G E L + +YA QFG + Sbjct: 257 SAANRL---GEEGTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIG 313 Query: 328 RNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARD 387 + QL+ KL +M + ++ +K+ + A S+ + +A + Sbjct: 314 KFQLVANKLVEMKLRLENAKAYLYKVAWMKENKQMALLEASMANLYISEAWVQSCLEAIE 373 Query: 388 MLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 + G G + R + A Y GT +I +++ + Sbjct: 374 IHGAYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAK 412 >5ZW7-A nrPDB Length = 402 Score = 114 bits (285), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 90/340 (26%), Positives = 153/340 (45%), Gaps = 31/340 (9%) Query: 107 GPTIKGYGCAGVSSVAYGLLARELER--VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY 164 GP +G + + ++ L+ L + D G ++ + P+Y +GS E + KY Sbjct: 53 GPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKY 112 Query: 165 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV 224 L L G+L+ TEP++GSD +M+ A Y LNG K +ITN+P+AD+F++ Sbjct: 113 LESLVTGKLIAANAATEPDAGSDIYNMQATAQ--PCEGGYILNGKKIFITNAPIADVFII 170 Query: 225 WARCEDG----CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA 280 +A+ + FL+EKG GL+ + K L I+ + + +P+ + Sbjct: 171 YAKTNPDHGFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGME 230 Query: 281 SSLGGPF--------GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLI 332 + G F GCL+ +G L T +YA R QFG + + Q + Sbjct: 231 GAGGAIFHDSMIWEKGCLSAL-------FVGGLARLLETTLEYAKARQQFGKAIGQFQSV 283 Query: 333 QKKLADM---LTEITLGLH-ACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDM 388 ++ DM L + L L+ AC + DQ + A +++ K A+ A Sbjct: 284 SNRIIDMKLRLEQCRLMLYRACWK----HDQGQDAEADIAMSKLLISEYAVQSGLDAIQT 339 Query: 389 LGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 GG + E ++RH +N+ + GT+DI I+ R + Sbjct: 340 FGGAAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKL 379 >5JSC-A nrPDB Length = 410 Score = 104 bits (260), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 82/288 (28%), Positives = 126/288 (43%), Gaps = 33/288 (11%) Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITN 215 G+ EQ+ +YLP++A G + F L+EP +GSD ++M A + +Y L+G KTWI+N Sbjct: 123 GTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSARED--GDAYVLDGDKTWISN 180 Query: 216 SPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEEN 275 +AD +VV+AR + G RG+SA F + A G+ I + ++V + Sbjct: 181 GGIADFYVVFARTGEA--------PGARGISA------FVVDADTPGLEIAERIDVIAPH 226 Query: 276 VL----------PGASSLGGP-------FGCLNNARYGIAWGVLGASEFCLHTARQYALD 318 L P + LG P L+ R +A LG + + A Sbjct: 227 PLARLHFAGARVPRSQMLGAPGEGFKLAMRTLDIFRTSVAAASLGFARHAMAEGVARAAS 286 Query: 319 RMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKA 378 R FG L QL Q KLA M I + L+DQ + ++ K + A Sbjct: 287 RKMFGQTLGDFQLTQAKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKWHASEGA 346 Query: 379 LDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 + A + GG G+ V + A+ YEG ++ LI+GR Sbjct: 347 QQVIDAAVQLYGGMGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGR 394 >1R2J-A nrPDB Length = 366 Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 80/279 (28%), Positives = 124/279 (44%), Gaps = 13/279 (4%) Query: 94 REIISEMGELGVLGPTIKG-YGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPI 152 R+++ +G G+L + +G G+ S G + + S RS M+ Q + + Sbjct: 27 RDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVMTSQG-MAAWTV 85 Query: 153 YAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTW 212 G QR +L +L G+L G +E +GSD S+M TR + + ++G K W Sbjct: 86 QRLGDAGQRATFLKELTSGKL-AAVGFSERQAGSDLSAMRTRVRLD--GDTAVVDGHKVW 142 Query: 213 ITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVP 272 T + AD VV+ EDG ++ G+ R+ RA+ + +D V VP Sbjct: 143 TTAAAYADHLVVFGLQEDGSGAVVVVPADTPGVRVERVPKPSGCRAAGHADLHLDQVRVP 202 Query: 273 EENVLPGA-SSLGGPF---GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLAR 328 VL G+ +SL P L R +AWG +G C A +A R QFG PL Sbjct: 203 AGAVLAGSGASL--PMLVAASLAYGRKSVAWGCVGILRACRTAAVAHARTREQFGRPLGD 260 Query: 329 NQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMV 367 +QL+ +AD+ T + C D+ +PEMV Sbjct: 261 HQLVAGHIADLWTAEQIAARVCEYAS--DHWDEGSPEMV 297 >3R7K-A nrPDB Length = 403 Score = 92.0 bits (227), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 92/368 (25%), Positives = 164/368 (44%), Gaps = 18/368 (4%) Query: 72 RTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYGLLAREL 130 R++ + + P++ R++ E+G+LG + G +G +++ L+ + Sbjct: 41 RSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVGGSGGNAIDSALVTEAI 100 Query: 131 ERV--DSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDP 188 +G +A+ + H I A GS+ ++Y+ G+++G G+TEP +GSD Sbjct: 101 LAAGGSTGVCAALFTHGIALPH-IAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDV 159 Query: 189 SSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED---GCIRGFLLEKGMRGL 245 +++ TRA +Y +NG KT+IT+ AD R G + +++K G Sbjct: 160 ANLRTRAV--REGDTYVVNGAKTFITSGVRADFVTTAVRTGGPGYGGVSLLVIDKNSPGF 217 Query: 246 SAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG--GPFGCLNNARYGIAWGVLG 303 R K R S T + V VP +N L GA + G R GIA Sbjct: 218 EVSRRLDKMGWRCSDTAELSFVDVRVPADN-LVGAENSGFLQIMQQFQAERLGIAVQAYA 276 Query: 304 ASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAA 363 + L A+ +A +R FG PL Q+I+ KLA+M ++ + AC + + A Sbjct: 277 TAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDV---ACTYTRAVMQRWLAG 333 Query: 364 PEMVS--LLKRNNCGKALD-IARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420 ++V+ + +N A D + +A + GG G E + RH + + GT++I Sbjct: 334 EDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRILGIGGGTNEIM 393 Query: 421 ALILGRAI 428 ++ + I Sbjct: 394 NEVIAKRI 401 >3P4T-A nrPDB Length = 403 Score = 89.0 bits (219), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 100/386 (25%), Positives = 161/386 (41%), Gaps = 21/386 (5%) Query: 47 EFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVL 106 E Q P + T + +R T R + + ++P R RE+ + ELG+L Sbjct: 13 EAQTQGPGSMSIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLL 72 Query: 107 GPTI-KGYGCAGVSSVAYGLLARELERVDS--GYRSAMSVQSSLVMHPIYAYGSEEQRQK 163 G + G +G ++ E+ S G +++ V H I A G + Sbjct: 73 GAGFPEDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMI-ASGDQRLIDT 131 Query: 164 YLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFV 223 Y+ +GE +G +TEP GSD + TRA + + Y +NG KT+IT+ AD V Sbjct: 132 YVRPTLRGEKIGALAITEPGGGSDVGHLRTRADLDGDH--YVINGAKTYITSGVRADYVV 189 Query: 224 VWARCED---GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA 280 AR G + +++KG G R K R+S T + V VP N L G+ Sbjct: 190 TAARTGGPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVAN-LVGS 248 Query: 281 SSLGGPFGCLNNA----RYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKL 336 + G F + A R G+A ++ CL ++ +R FG PL Q +Q L Sbjct: 249 ENTG--FAQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTL 306 Query: 337 ADMLTEITLGLHACLQLGRLKDQDKAAPEMVS--LLKRNNCGKALD-IARQARDMLGGNG 393 A M I + + ++ Q +++ +N +A + +A QA + GG G Sbjct: 307 AGMARRIDVARVYTRHV--VERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMG 364 Query: 394 ISDEYHVIRHAMNLEAVNTYEGTHDI 419 E V R ++ + GT +I Sbjct: 365 YMAESEVERQYRDMRILGIGGGTTEI 390 >6CY8-B nrPDB Length = 380 Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 13/215 (6%) Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSME 192 D+G A + + PI +GSE + + LP LA G + ++E ++GSD S++ Sbjct: 79 TDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLATGRKIAANAISEASAGSDISNLA 138 Query: 193 TRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC--EDGCI--RGFLLEKGMRGLSAP 248 T A Y LNG K+++TN +AD +VV+A + G + F++ + G+S Sbjct: 139 TTAQ--KEGDYYVLNGGKSYVTNGSIADYYVVYATTNKKHGYLGQTAFVVPRNTPGISVG 196 Query: 249 RIQGKFSLRASATGMIIMDGVEVPEENVL----PGASSLGGPFGCLNNARYGIAWGVLGA 304 K LR++ + D + ++ L GA + I +GA Sbjct: 197 NDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGARIFAASMDWERCCLFAI---FVGA 253 Query: 305 SEFCLHTARQYALDRMQFGVPLARNQLIQKKLADM 339 + L+ +YA RMQ ++R Q + ++ADM Sbjct: 254 MQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADM 288 >5AHS-A nrPDB Length = 401 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 76/300 (25%), Positives = 131/300 (43%), Gaps = 21/300 (7%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG---PTIKGYGC 115 +LT ++ ++ R Q + + E + + ++++ + G +G PT G Sbjct: 3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPT--SVGG 60 Query: 116 AGVSSVAYGLLARELERVDSGYRSAMSVQSSL-VMHPIYAYGSEEQRQKYLPQLAKGELL 174 G+S++ ++ E+ + ++V S+L + I YGSEEQ + + G+ Sbjct: 61 RGLSTLDTVIVIEEMAKA-CATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDK- 118 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC-EDGCI 233 ++EPN+GS S M TRA N + Y LNG K WIT ++ L +++AR +DG Sbjct: 119 PAICISEPNAGSAASEMTTRADKNGDH--YILNGEKYWITGGGVSKLHLIFARVFDDGVE 176 Query: 234 RGF------LLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPF 287 +G L + G GL R +R + +++ + ++ L F Sbjct: 177 QGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGF 236 Query: 288 GCL----NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEI 343 L N R G LG ++ Y R QFG PLA Q +Q +ADM ++ Sbjct: 237 AALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQL 296 >5EZ3-A nrPDB Length = 573 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 75/277 (27%), Positives = 123/277 (44%), Gaps = 28/277 (10%) Query: 170 KGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE 229 +G LG G+TE G+D + TRA + ++ L G K W ++PM+D F+ A+ + Sbjct: 205 QGVTLG-MGMTEKQGGTDVRANATRAE-PAIGGAWRLTGHK-WFMSAPMSDAFLTLAQTK 261 Query: 230 DGCIRGFLL----EKG-MRGLSAPRIQGKFSLRASATGMIIMDG-----VEVPEENVLPG 279 +G + FLL EKG G R++ K R++A+ + DG + P E V Sbjct: 262 EG-LSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGV--- 317 Query: 280 ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADM 339 + R A G L A ++ R FG PL L+Q+ LADM Sbjct: 318 ----KTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADM 373 Query: 340 LTEITLGLHACLQLGRLKD---QDKA----APEMVSLLKRNNCGKALDIARQARDMLGGN 392 ++ ++L R D D+A A M ++K C A + +A + LGGN Sbjct: 374 ALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGN 433 Query: 393 GISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT 429 G ++ ++ R +EG+ ++ AL + R ++ Sbjct: 434 GYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLS 470 >4HR3-A nrPDB Length = 415 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 72/297 (24%), Positives = 127/297 (42%), Gaps = 27/297 (9%) Query: 149 MHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLN 207 M ++ YGS+EQ++ +L L +G++ F +TEP+ + SD ++M A +N Sbjct: 118 MEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGD--EVVIN 175 Query: 208 GTKTWIT--NSPMADLFVVWARCEDGCIR-----GFLLEKGMRGLSAPRIQGK--FSLRA 258 G K W T P + + + R L+ G++ R+ F Sbjct: 176 GRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEP 235 Query: 259 SATGMIIMDGVEVPEENVLPGASSLGGPF----GCLNNARYGIAWGVLGASEFCLHTARQ 314 G++ D V +P + + G G F G L R A ++G +E L A + Sbjct: 236 GGHGVVSFDNVRLPADAFIAGP---GKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACR 292 Query: 315 YALDRMQFGVPLARNQLIQKKLADMLTEIT----LGLHACLQLGRLKDQDK-AAPEMVSL 369 LDR FG PL ++++AD I L LHA L + +A + + Sbjct: 293 RGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKV 352 Query: 370 LKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 N + +D+A Q + GG G+S+++ + +N A+ +G ++H ++ R Sbjct: 353 AAPNMAQQVIDMAIQ---IHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVAR 406 >4RM7-A nrPDB Length = 391 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 82/323 (25%), Positives = 137/323 (42%), Gaps = 18/323 (5%) Query: 125 LLARELERVDSGYRSAMSVQSSLV-MHPIYAYGSEEQRQKYLPQLAK-GELLGCFGLTEP 182 L+ EL R+ SG + + Q+ L+ + + A+ S Q + + G L ++EP Sbjct: 75 LVIEELSRI-SG--ACLPFQNDLLQLQILEAFASSAQTSPFRTEYQDTGRLSYALAISEP 131 Query: 183 NSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC-----IRGFL 237 +GSD SM R H + +NGTK ++ N A +V A + G ++ Sbjct: 132 EAGSDTRSM--RTHVTREGDTLVMNGTKMFVNNGEYAPALLVSAYDKTGDDGEPEFSFWM 189 Query: 238 LEKGMRGLSA-PRIQGKFSLRASATGMIIMDGVEVPEENVLPGASS-LGGPFGCLNNARY 295 + + G+ A P + S+ AT + D VEV E L G+S + L R Sbjct: 190 VPRSAAGIYAYPEQKIGQSMLPFAT--VRFDNVEVKESWRLKGSSKGFSQLYSLLEYGRV 247 Query: 296 GIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGR 355 LG ++ + A +A R FG +A Q +Q KL +M ++T + R Sbjct: 248 FTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTNMRNLVYGAAR 307 Query: 356 LKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEG 415 D+ + V+L+K A ++A A +LGG G E V + +G Sbjct: 308 EYDRGEHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQDCRGYQFADG 367 Query: 416 THDIHALILGRAITGIQAFTASK 438 T ++ +I I ++ + ASK Sbjct: 368 TDEVMVVIAAPLI--LEQYKASK 388 >2WBI-A nrPDB Length = 428 Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 77/330 (23%), Positives = 138/330 (41%), Gaps = 36/330 (10%) Query: 116 AGVSSVAYGLLARELERVDSGYRSAMSVQSSLV--MHPIYAYGSEEQRQKYLPQLAKGEL 173 +G+S V Y L+A E + + Q+ M ++ YGSEEQ++++L L +G + Sbjct: 90 SGLSHVDYALIAEETGKCFFA-PDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNI 148 Query: 174 LGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS--PMADLFVVWARCED 230 CF +TEP+ + SD +++E + SY +NG K W + + P + +V R ++ Sbjct: 149 TSCFCMTEPDVASSDATNIECSIQRDED--SYVINGKKWWSSGAGNPKCKIAIVLGRTQN 206 Query: 231 GCIRG------FLLEKGMRGLSAPRIQGKFSLRASATG---MIIMDGVEVPEENVLPGAS 281 + L+ G+ R F + G I + V VP N++ G Sbjct: 207 TSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGE- 265 Query: 282 SLGGPF----GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLA 337 G F G L R +G +E L + A R+ F L ++++ +A Sbjct: 266 --GRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIA 323 Query: 338 D---MLTEITL----GLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLG 390 + + +I L H+ LG + + A M+ + K +D A Q + G Sbjct: 324 ESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIA--MIKVAAPRAVSKIVDWAIQ---VCG 378 Query: 391 GNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420 G G+S +Y + + +G ++H Sbjct: 379 GAGVSQDYPLANMYAITRVLRLADGPDEVH 408 >4X28-A nrPDB Length = 400 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 43/136 (31%), Positives = 71/136 (52%), Gaps = 12/136 (8%) Query: 93 HREIISEMGELGVLG---PTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVM 149 +RE I++MG G L P K YG G S++ + E + +++ S V Sbjct: 45 YRETIAQMGRDGWLALGWP--KEYGGQGRSAMDQLIFTDEAA-IAGAPVPFLTINS--VA 99 Query: 150 HPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGT 209 I AYG++EQ++ +LP++A G+L G +EP +G+D +++ T A + + Y +NG Sbjct: 100 PTIMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDD--YVVNGQ 157 Query: 210 KTWITNSPMADLFVVW 225 K W + AD VW Sbjct: 158 KMWTSLIQYADY--VW 171 >5Y9D-A nrPDB Length = 709 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 35/225 (15%) Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQ--LAKGELLGCFGLTEPNSGSDPSS 190 VD R+ +S+ ++L + I G+ EQ + ++ + +A + GCF +TE GS+ Sbjct: 120 VDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKG 179 Query: 191 METRAHYNSSNKSYTLN-----GTKTWITNSPMADLF-VVWARC----EDGCIRGFLL-- 238 +ET A Y+ + + +N TK WI + V +A+ +D R F++ Sbjct: 180 LETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPL 239 Query: 239 ----EKGMR-GLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL--------------PG 279 + ++ G+S I K G I V +P +N+L P Sbjct: 240 RNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPA 299 Query: 280 ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGV 324 L +G L R + S+ L A +YA R QFG Sbjct: 300 LDQL--TYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGT 342 >5YS9-A nrPDB Length = 708 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 86/357 (24%), Positives = 130/357 (36%), Gaps = 62/357 (17%) Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLA---KGELLGCFGLTEPNSGSDPS 189 VD G R + V + L M I G++EQ ++ + A KG GCF +TE GS+ + Sbjct: 114 VDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKG-FYGCFAMTELGHGSNVA 172 Query: 190 SMETRAHYNSSNKSYTLN-----GTKTWITNSPM-ADLFVVWARC----EDGCIRGFLLE 239 +ET A Y + +N TK WI + A +AR +D ++ F+++ Sbjct: 173 GLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVVQ 232 Query: 240 -------KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL---PGASSLGG---- 285 M G++ I K A G I V +P +N+L SS G Sbjct: 233 LRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQP 292 Query: 286 -----PFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFG----------------- 323 +G L R + S+ + A +YA R QFG Sbjct: 293 PLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQ 352 Query: 324 ---VPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSL---------LK 371 +PL K AD LQ KD+ +V L LK Sbjct: 353 RRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGLK 412 Query: 372 RNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 +I Q R GG+G S + + T+EG +++ L +GR + Sbjct: 413 AFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGL 469 >2FON-A nrPDB Length = 683 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 20/151 (13%) Query: 147 LVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSY-- 204 + + I G+++Q++K+LP K +++GC+ TE GS+ +ET A ++ + Sbjct: 124 MFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVI 183 Query: 205 ---TLNGTKTWITN-SPMADLFVVWARC----EDGCIRGFLLE-------KGMRGLSAPR 249 TL +K W ++ VV+AR +D + GF+++ K + G++ Sbjct: 184 HSPTLTSSKWWPGGLGKVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVTVGD 243 Query: 250 IQGKF---SLRASATGMIIMDGVEVPEENVL 277 I KF + + G++ D V +P + +L Sbjct: 244 IGMKFGNGAYNSMDNGVLSFDHVRIPRDQML 274 >3U33-A nrPDB Length = 541 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 69/288 (23%), Positives = 111/288 (38%), Gaps = 24/288 (8%) Query: 157 SEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS 216 S+ LP K LL G+TE GSD S TRA + SY L G K W + Sbjct: 162 SDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAE-RLEDGSYRLVGHK-WFFSV 219 Query: 217 PMADLFVVWARCEDGC----IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVP 272 P +D +V A+ G + FL + + R++ K R++A+ EV Sbjct: 220 PQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNAS-------CEVE 272 Query: 273 EENVLPGASSLGGP-----FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLA 327 ++ + L G R+ A G A +A R FG PL Sbjct: 273 FQDAIGWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLI 332 Query: 328 RNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPE------MVSLLKRNNCGKALDI 381 + L++ L+ M ++ +L R D+ A E K C + + Sbjct: 333 QQPLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPF 392 Query: 382 ARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT 429 +A ++LGG G +E + R + + +EG+ +I L + R + Sbjct: 393 VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLN 440 >4XVX-A nrPDB Length = 389 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 69/295 (23%), Positives = 122/295 (41%), Gaps = 22/295 (7%) Query: 76 QERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDS 135 ER++ A E F R++I +G GV V + LA L ++ S Sbjct: 22 DERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVE--LAFALGQLAS 79 Query: 136 -GYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETR 194 G +S+ S + + +G + + Q +G + C G +E + GSD +ET Sbjct: 80 AGIGVGVSLHDSAIA-ILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVET- 137 Query: 195 AHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED-------GCIRGFLLEKGMRGLSA 247 S + + + G K +++ SP+AD +V AR D G + + + Sbjct: 138 -EIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQT 196 Query: 248 P-RIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPFGCLNNARYGIAWGVLGAS 305 P R G L +A + +D VP + ++ A + L L + R IA + + Sbjct: 197 PYRKVGAGPLDTAA---VCID-TWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASC 252 Query: 306 EFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITL---GLHACLQLGRLK 357 + + + R QFG L +Q ++ ++AD+ + L LH + GRL+ Sbjct: 253 QRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLE 307 >5GJ7-A nrPDB Length = 398 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 63/250 (25%), Positives = 101/250 (40%), Gaps = 32/250 (12%) Query: 180 TEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRG-FLL 238 TEP +GS + Y + G KT+ T SP +V A D + G FL+ Sbjct: 134 TEPATGSPSRGGKPETTAVKVPGGYRITGRKTFSTLSPALTWIMVTATVADEDVVGQFLV 193 Query: 239 EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL----PGASSLGGPFGC----- 289 K + +RA+ + I++ V VPEE V+ PG + P G Sbjct: 194 RK--EDVEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQRPGVQAERRPDGSGWLLH 251 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 + GIA L A +F L A Y + + P+A +++KL +M E+ L Sbjct: 252 IPACYLGIA---LAARDFALEYAATYRPNTLPH--PIAEVPHVEQKLGEM--ELKLLAAR 304 Query: 350 CLQLGRLKDQDKAAPE----------MVSLLKRNNCGKALDIARQARDMLGGNGISDEYH 399 L + D A+PE V L N + +D+A + ++GG +S Sbjct: 305 TLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMR---VVGGRSLSRALP 361 Query: 400 VIRHAMNLEA 409 + R+ ++ A Sbjct: 362 LERYYRDVRA 371 >4ZYJ-A nrPDB Length = 425 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 54/205 (26%), Positives = 92/205 (44%), Gaps = 23/205 (11%) Query: 87 NRNEVFHREIISEMGELGVLGPTIK----GYGCAGVSSVAYGLLARELERVDSGYRSAMS 142 +R + M + GVLG T+ G G + VA L AR R D+G A+ Sbjct: 68 DREATLPVHLFDRMRKEGVLGATVPEDLGGLGVHSLHDVALAL-ARIAGR-DAGVALALH 125 Query: 143 VQSS--LVMHPIYAYGSEEQR---QKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHY 197 +Q S L + + +G+ R + L Q+ GE + C + + +++ TRA Sbjct: 126 MQFSRGLTLDFEWRHGAPSTRPLAEDLLRQMGAGEAVICGAVKDVRG----TTVLTRA-- 179 Query: 198 NSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEKGMRGLSAPRIQGK 253 ++ SY LNG KT ++ + +A +VV R E+ + ++ + GL+ Sbjct: 180 --TDGSYRLNGRKTLVSMAGIATHYVVSTRLEEAGAPVRLAAPVVARTTPGLTVLDNWDG 237 Query: 254 FSLRASATGMIIMDGVEVPEENVLP 278 +R+S + I+ DG V + VLP Sbjct: 238 MGMRSSGSVDIVFDGCPVDRDRVLP 262 >5K3J-A nrPDB Length = 674 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 39/173 (22%), Positives = 76/173 (43%), Gaps = 32/173 (18%) Query: 130 LERVDSGYR-SAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDP 188 L R GY ++ +L + + + S+EQ++K+L + + E++GC+ TE GS+ Sbjct: 99 LHREVIGYEGHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNL 158 Query: 189 SSMETRAHYNSSNKSYTLNGTKT----WIT--------------------NSPMADLFVV 224 ++ET A Y+ +++ + L+ T W N+ F+V Sbjct: 159 RNLETTAVYDIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRNNYGPHFFMV 218 Query: 225 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL 277 R E I ++G++ I K + A+ G + ++ + VP N+L Sbjct: 219 QLRDEKTHI-------PLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTNLL 264 >1W07-A nrPDB Length = 659 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 53/226 (23%), Positives = 92/226 (40%), Gaps = 40/226 (17%) Query: 152 IYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLN---- 207 I G+EEQ++K+L K +++GC+ TE GS+ +ET A + + ++ Sbjct: 110 IKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQ 169 Query: 208 -GTKTWITN-SPMADLFVVWARC----EDGCIRGFLLEKGMRGLSA----PRI------- 250 +K W ++ VV+AR +D I GF+++ +R L P I Sbjct: 170 TASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQ--LRSLEDHSPLPNITVGDIGT 227 Query: 251 -QGKFSLRASATGMIIMDGVEVPEENVL-------------PGASSLGGPFGCLNNARYG 296 G + + G ++ D V +P + +L P +G + R Sbjct: 228 KMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQT 287 Query: 297 IAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTE 342 I A + A +Y+ R QFG A N I+ ++ D T+ Sbjct: 288 IVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQ 330 >4X28-D nrPDB Length = 373 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 16/190 (8%) Query: 155 YGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWIT 214 +GS E +Q + G+ + L + G P H Y L GT+T + Sbjct: 101 FGSPELQQGWGVSAVSGDRILTVAL-DGEMGEGPVQAAGTGH------GYRLTGTRTQVG 153 Query: 215 NSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEE 274 P+AD F+V A + G FL+ G G++ + + + G + ++G +V Sbjct: 154 YGPVADAFLVPAETDSGAAV-FLVAAGDPGVAVTALA---TTGLGSVGHLELNGAKVDAA 209 Query: 275 NVLPGASSLGGPFGCLNN-ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQ 333 + G + + G L+ +R GVL E L +YA R QF P+ Q + Sbjct: 210 RRV-GGTDVAVWLGTLSTLSRTAFQLGVL---ERGLQMTAEYARTREQFDRPIGSFQAVG 265 Query: 334 KKLADMLTEI 343 ++LAD ++ Sbjct: 266 QRLADGYIDV 275 >1IS2-A nrPDB Length = 661 Score = 37.0 bits (84), Expect = 0.015, Method: Compositional matrix adjust. Identities = 36/162 (22%), Positives = 65/162 (40%), Gaps = 17/162 (10%) Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSME 192 V G+ + + + + + + EQ++++ E+ G + TE G+ +E Sbjct: 92 VHRGHPEPLDLHLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLE 151 Query: 193 TRAHYNSSNKSYTLNG-TKTWITNSP-----MADLFVVWAR--CEDGC---------IRG 235 T A Y+ + + LN T T I P ++ +V A+ + C IR Sbjct: 152 TTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIRE 211 Query: 236 FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL 277 K + G++ I KF G + MD +P EN+L Sbjct: 212 IGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 >5K3G-A nrPDB Length = 684 Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 39/70 (55%) Query: 141 MSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSS 200 M++ + + + A S+EQ+ K+L + + E++G + TE G++ ++ET A Y+ Sbjct: 113 MALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIG 172 Query: 201 NKSYTLNGTK 210 + + L+ K Sbjct: 173 TQEFVLHTPK 182 >3M9V-A nrPDB Length = 439 Score = 34.7 bits (78), Expect = 0.083, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 9/94 (9%) Query: 204 YTLNGTKTWITNSPMADLFVVWARCE--DGCIR--GFLLEKGMRGLSAPRIQGKFSLRAS 259 + L+G KT ++ +P+ FV+ AR + DG R ++ + G + +RAS Sbjct: 163 WLLSGRKTLVSMAPVGTHFVINARTDGTDGPPRLASPVVTRDTPGFTVLDNWDGLGMRAS 222 Query: 260 ATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNA 293 T I+ D +P ++VL + P G N+A Sbjct: 223 GTVDIVFDDCPIPADHVL-----MRDPVGARNDA 251 >4JEK-A nrPDB Length = 453 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 85/369 (23%), Positives = 133/369 (36%), Gaps = 68/369 (18%) Query: 94 REIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDS--GYRSAMSVQSSLVMHP 151 RE + G L +L P + YG G + RE+ D G+ + ++ ++ Sbjct: 85 REDLRASGLLSLLVP--REYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLTNAPMIEL 142 Query: 152 IYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKT 211 I GS+EQ + Q+A+ +E NS + + + Y LNGTK Sbjct: 143 I---GSQEQEEHLYTQIAQNNWWTGNASSENNSHVLDWKVSATP---TEDGGYVLNGTKH 196 Query: 212 WITNSPMADLFVVWARCED-----GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIM 266 + + + +DL V+ +D G I + G++ +R + +G Sbjct: 197 FCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDF 256 Query: 267 DGVEVPEENVL--PGA----------SSLGGPFGCL--NNARYGIAWGVLGASEFCLHTA 312 V+V + VL P A SL P L N GIA G L A A Sbjct: 257 HNVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDA-------A 309 Query: 313 RQYALDRMQFGVPLARNQLIQKKLADMLT-----EITLGLHACLQ--------LGRLKDQ 359 R+Y + + P IQ+ D T E T+ L L + D+ Sbjct: 310 REYTRTQARPWTPAG----IQQATEDPYTIRSYGEFTIALQGADAAAREAAHLLQTVWDK 365 Query: 360 -DKAAPE-------MVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVN 411 D PE VS +K AL+I+ +++G G Y R N+ Sbjct: 366 GDALTPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVR--- 422 Query: 412 TYEGTHDIH 420 TH +H Sbjct: 423 ----THSLH 427 >5T33-G nrPDB Length = 357 Score = 31.2 bits (69), Expect = 0.95, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 12/113 (10%) Query: 182 PNSGSDPS------SMETRAHYNSSNKSYTLNGTKTW---ITNSPMADLFVVWARCEDGC 232 P+SG DP + Y ++ K +T TW N+ ++ V+ C Sbjct: 229 PSSGGDPEIVMHSFNCNGEFFYCNTTKLFTSTWNSTWNSTWNNTEGSNSTVITLPCRIRQ 288 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMD--GVEVPEENVLPGASSL 283 I E G + + AP IQG+ ++ TG+++ GV+ +E PG ++ Sbjct: 289 IINMWQEVG-KAMYAPPIQGQIKCSSNITGLLLTRDGGVDTTKETFRPGGGNM 340 >1J49-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 348 HACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGG 391 HA +Q R+ QDKA E V+ R++ A I R+ RD + G Sbjct: 110 HAAIQAARILRQDKAMDEKVA---RHDLRWAPTIGREVRDQVVG 150 >4GO4-A nrPDB Length = 495 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 1/68 (1%) Query: 331 LIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIA-RQARDML 389 ++ K +AD E + L ++LG D + + S L+R+ +DIA Q +L Sbjct: 288 ILHKDIADQFLERFIALAKSIRLGDPMDPETEMGPLTSALRRDRVLSYIDIAIEQGGKVL 347 Query: 390 GGNGISDE 397 G D+ Sbjct: 348 AGGKAPDD 355 >6QM4-A nrPDB Length = 735 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 12/95 (12%) Query: 42 KSSRPEFDW----QDPL------VLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEV 91 + SRPEF+W +DP+ V L++ F C L I+ N EV Sbjct: 255 QQSRPEFEWEHEAEDPITGEPVKVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEV 314 Query: 92 FHREIISEMGE--LGVLGPTIKGYGCAGVSSVAYG 124 F E+ S G+ LG L G +S V G Sbjct: 315 FINEVYSGPGKQYLGFLPTIFLVIGTPTISGVLMG 349 >1IHU-A nrPDB Length = 589 Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 22/126 (17%) Query: 1 MALRGVSVRLLSRGPGLHVLRTW--------VSSAAQTEKGGRTQSQLAKSSRPEFDWQD 52 +A G V L + P H+ T VS E+ R + + ++ E D Sbjct: 351 LADMGFDVHLTTSDPAAHLSMTLNGSLNNLQVSRIDPHEETERYRQHVLETKGKELDEAG 410 Query: 53 PLVLEEQL---TTDEI--------LIRDTFRTYCQERLMPR---ILLANRNEVFHREIIS 98 +LEE L T+EI +IR+ + + P +LL + +HREI Sbjct: 411 KRLLEEDLRSPCTEEIAVFQAFSRVIREAGKRFVVMDTAPTGHTLLLLDATGAYHREIAK 470 Query: 99 EMGELG 104 +MGE G Sbjct: 471 KMGEKG 476 >5MLG-A nrPDB Length = 389 Score = 27.7 bits (60), Expect = 9.9, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 17/117 (14%) Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRG 244 GSDP + HY S +K+ + T ++ P L CE+GC+ +++ G Sbjct: 220 GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLL------CEEGCMA--VVDTGTSY 271 Query: 245 LSAPR-----IQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGGPFGCLNNARY 295 +S P I ++ +++ +VP LP S LGG L+N Y Sbjct: 272 ISGPTSSLQLIMQALGVKEKRANNYVVNCSQVP---TLPDISFYLGGRTYTLSNMDY 325 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1SIR-A nrPDB 514 e-146 3GNC-A nrPDB 464 e-131 4N5F-A nrPDB 462 e-130 4L1F-A nrPDB 459 e-129 1JQI-A nrPDB 459 e-129 5LNX-A nrPDB 458 e-129 3SF6-A nrPDB 456 e-129 5OL2-C nrPDB 454 e-128 4W9U-A nrPDB 449 e-126 2VIG-A nrPDB 447 e-126 4M9A-A nrPDB 441 e-124 4U83-A nrPDB 437 e-123 1UKW-A nrPDB 434 e-122 2A1T-A nrPDB 430 e-121 2EBA-A nrPDB 428 e-120 1BUC-A nrPDB 428 e-120 3MDE-A nrPDB 427 e-120 6FAH-C nrPDB 426 e-120 4O5M-A nrPDB 424 e-119 1IVH-A nrPDB 423 e-119 3SWO-A nrPDB 419 e-117 4KTO-A nrPDB 417 e-117 2JIF-A nrPDB 416 e-117 2IX5-A nrPDB 409 e-114 2DVL-A nrPDB 407 e-114 3PFD-A nrPDB 405 e-113 2PG0-A nrPDB 393 e-109 1RX0-A nrPDB 392 e-109 4IV6-A nrPDB 388 e-108 2Z1Q-A nrPDB 388 e-108 3NF4-A nrPDB 385 e-107 3OWA-A nrPDB 381 e-106 3MPI-A nrPDB 378 e-105 4IRN-A nrPDB 373 e-104 2CX9-A nrPDB 365 e-101 6ES9-A nrPDB 353 9e-98 3B96-A nrPDB 351 2e-97 3R7K-A nrPDB 345 2e-95 5ZW7-A nrPDB 333 8e-92 3P4T-A nrPDB 330 8e-91 5IDU-A nrPDB 321 4e-88 5AHS-A nrPDB 303 2e-82 6CY8-B nrPDB 299 2e-81 5JSC-A nrPDB 297 5e-81 4RM7-A nrPDB 268 3e-72 4HR3-A nrPDB 267 9e-72 2WBI-A nrPDB 263 1e-70 1R2J-A nrPDB 252 2e-67 5YS9-A nrPDB 240 9e-64 5Y9D-A nrPDB 226 2e-59 3U33-A nrPDB 224 5e-59 5EZ3-A nrPDB 212 3e-55 5GJ7-A nrPDB 201 4e-52 4XVX-A nrPDB 200 1e-51 4X28-A nrPDB 199 2e-51 4X28-D nrPDB 190 1e-48 1W07-A nrPDB 189 2e-48 2FON-A nrPDB 188 4e-48 4ZYJ-A nrPDB 185 4e-47 5K3J-A nrPDB 164 7e-41 Sequences not found previously or not previously below threshold: 4Y9J-A nrPDB 169 3e-42 3M9V-A nrPDB 168 4e-42 3MXL-A nrPDB 158 5e-39 1IS2-A nrPDB 156 2e-38 5K3G-A nrPDB 155 3e-38 3MKH-A nrPDB 140 2e-33 2C12-A nrPDB 138 3e-33 5XDD-A nrPDB 128 4e-30 4JEK-A nrPDB 122 3e-28 2JBS-A nrPDB 89 5e-18 2RFQ-A nrPDB 82 5e-16 3AFF-A nrPDB 74 1e-13 5LVW-A nrPDB 72 7e-13 2OR0-A nrPDB 57 2e-08 1U8V-A nrPDB 40 0.002 2YYI-A nrPDB 33 0.19 4Q0M-A nrPDB 32 0.62 1AKL-A nrPDB 31 1.4 4QNW-A nrPDB 30 1.5 1WYZ-A nrPDB 30 1.9 2Q3R-A nrPDB 30 2.4 4C2U-A nrPDB 29 4.9 4C2T-A nrPDB 29 5.2 2VFA-A nrPDB 29 5.5 1GPU-A nrPDB 29 5.5 4EWC-A nrPDB 28 9.2 5OQL-E nrPDB 28 9.5 >1SIR-A nrPDB Length = 394 Score = 514 bits (1323), Expect = e-146, Method: Composition-based stats. Identities = 394/394 (100%), Positives = 394/394 (100%) Query: 45 RPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELG 104 RPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELG Sbjct: 1 RPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELG 60 Query: 105 VLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY 164 VLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY Sbjct: 61 VLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY 120 Query: 165 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV 224 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV Sbjct: 121 LPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVV 180 Query: 225 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG 284 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG Sbjct: 181 WARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG 240 Query: 285 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 344 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT Sbjct: 241 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 300 Query: 345 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 404 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA Sbjct: 301 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 360 Query: 405 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK 438 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK Sbjct: 361 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK 394 >3GNC-A nrPDB Length = 399 Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 255/398 (64%), Positives = 302/398 (75%), Gaps = 6/398 (1%) Query: 41 AKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEM 100 + F W DPL+L++QL DE ++RD Y Q +L PR+ A R+E I EM Sbjct: 3 GSMAAATFHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREM 62 Query: 101 GELGVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEE 159 GE+G+LGPTI + YG G+ V+YGL+ARE+ERVDSGYRS MSVQSSLVM PI+ +GS+ Sbjct: 63 GEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDA 122 Query: 160 QRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMA 219 Q++KYLP+LA GE +GCFGLTEPN GSDP SM TRA Y+L+G+K WITNSP+A Sbjct: 123 QKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRA--RKVPGGYSLSGSKMWITNSPIA 180 Query: 220 DLFVVWARCEDGC---IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENV 276 D+FVVWA+ ++ IRGF+LEKG +GLSAP I GK LRAS TG I++D VPEEN+ Sbjct: 181 DVFVVWAKLDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENI 240 Query: 277 LPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKL 336 LP L GPF CLN+ARYGIAWG LGA+E C H ARQY LDR QFG PLA NQLIQKKL Sbjct: 241 LPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKL 300 Query: 337 ADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISD 396 ADM TEITLGL L+LGR+KD+ AA E+ S++KRN+CGKALDIAR ARDMLGGNGISD Sbjct: 301 ADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISD 360 Query: 397 EYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAF 434 E+ V RH +NLE VNTYEGTHDIHALILGRA TGIQAF Sbjct: 361 EFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAF 398 >4N5F-A nrPDB Length = 385 Score = 462 bits (1189), Expect = e-130, Method: Composition-based stats. Identities = 113/379 (29%), Positives = 182/379 (48%), Gaps = 8/379 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYG 114 ++E T D+ +IRD R + E L P + + I++++GELG+LG + G Sbjct: 9 MDELYTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELG 68 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 + VAY L E+ D+ + MSV +S+ PI +G+ Q+ ++L +A G ++ Sbjct: 69 GSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVI 128 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG--- 231 G F LTEP++GS+ +++ TRA + + LNG K ++TN A + +V+A + Sbjct: 129 GAFCLTEPHAGSEANNLRTRAELR--DGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEAGK 186 Query: 232 -CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLP-GASSLGGPFGC 289 I FL+ G + + K +RAS T I + +PE+N+L L Sbjct: 187 RGISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALSN 246 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L R GIA LG + AR+YA +R+QFG P+A +Q IQ+KLADM +I Sbjct: 247 LEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLL 306 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 +L+ S K A + A + GG G +Y V RH + Sbjct: 307 VHHAAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARI 366 Query: 410 VNTYEGTHDIHALILGRAI 428 YEGT ++ +++ R + Sbjct: 367 TQIYEGTSEVQRMVIARQL 385 >4L1F-A nrPDB Length = 383 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 124/380 (32%), Positives = 199/380 (52%), Gaps = 8/380 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYG 114 ++ LT D+ +I+D + ++ L P + ++ ++ R++I +MGE G G + YG Sbjct: 1 MDFNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 G+ ++Y L EL +VD G +S SL PIY +G+EEQ+QKYL +A+G + Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG--- 231 G FGLTEP++G+D S+ +T A Y LNG+K +ITN AD +VV+A + Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVL--KGDKYILNGSKIFITNGKEADTYVVFAMTDKSQGV 178 Query: 232 -CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPFGC 289 I F+LEKGM G +I+ K S T +I + EVP+EN+L Sbjct: 179 HGISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAMET 238 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L+ R G+A LG +E L A +Y+ +R QFG +++ Q +Q +ADM T+I + Sbjct: 239 LDGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARYL 298 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 LK++ K E ++ K A+++ A + GG G + +Y R+ N + Sbjct: 299 VYHAAMLKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAKI 358 Query: 410 VNTYEGTHDIHALILGRAIT 429 YEGT+ + ++ RA+ Sbjct: 359 TQIYEGTNQVMRIVTSRALL 378 >1JQI-A nrPDB Length = 388 Score = 459 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 117/377 (31%), Positives = 184/377 (48%), Gaps = 8/377 (2%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 +L ++R T R + ++ L+P ++ +F + +MGELG+L + + AG Sbjct: 9 ELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAG 68 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 + +AY + E+ R + MSV +SL + PI +GS +Q+Q+++ G+ +GCF Sbjct: 69 LDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCF 128 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCI 233 L+EP +GSD + T A S+ LNGTK WITNS A VV+A + + I Sbjct: 129 ALSEPGNGSDAGAASTTA--REEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGI 186 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGGPFGCLNN 292 FL+ GL+ + + K +RAS+T +I + +P+EN+L L+ Sbjct: 187 SAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDM 246 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R GIA LG ++ L A +YA +R FG PL + Q IQ KLADM + + Sbjct: 247 GRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWR 306 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 LKD K + ++ K A I+ QA +LGG G E R+ + Sbjct: 307 AAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEI 366 Query: 413 YEGTHDIHALILGRAIT 429 YEGT +I L++ + Sbjct: 367 YEGTSEIQRLVIAGHLL 383 >5LNX-A nrPDB Length = 379 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 127/378 (33%), Positives = 193/378 (51%), Gaps = 8/378 (2%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTIKGYGCAG 117 +T +++++R R + ++ + P + + + F ++I +MG+ G++G P + YG AG Sbjct: 2 HVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAG 61 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 V+Y L E+ R+ + +SV +S+ +PI +G+EEQ+ KY+P LA G+ LG F Sbjct: 62 ADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAF 121 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG----CI 233 LTEP+SGSD S+ T A N Y LNG+K +ITN AD+++ +A I Sbjct: 122 ALTEPHSGSDAGSLRTTAI--KKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGI 179 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPFGCLNN 292 F++EK G + + + K L S T +I D EVPE N+L LN Sbjct: 180 SAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNV 239 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R GIA LG +E L A YA R+QFG P+A NQ I KLADM T H Sbjct: 240 GRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYH 299 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L ++ + S+ K+ A+ A A + GG G +Y V R + + Sbjct: 300 AADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQI 359 Query: 413 YEGTHDIHALILGRAITG 430 YEGT++I LI+ + + G Sbjct: 360 YEGTNEIQRLIISKYLLG 377 >3SF6-A nrPDB Length = 403 Score = 456 bits (1174), Expect = e-129, Method: Composition-based stats. Identities = 200/404 (49%), Positives = 264/404 (65%), Gaps = 4/404 (0%) Query: 33 GGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVF 92 G T S +A+ D + + L+ +E IRDT R+ Q R+ P I + Sbjct: 3 GSMTNSAVAQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGEL 62 Query: 93 H-REIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHP 151 RE+ E+GELG+LG +KGYGCAG+S+VAYGL ELE DSG RS +SVQ SL M+ Sbjct: 63 PARELAVELGELGLLGMHLKGYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYA 122 Query: 152 IYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKT 211 I+A+GS+EQ+ ++LP +A G +GCFGLTEP+ GSDP+ M TRA + + + L GTK Sbjct: 123 IHAFGSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATRSGDD--WILTGTKM 180 Query: 212 WITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEV 271 WITN +AD+ VVWAR ++G IRGF++ G +A I+ K SLRAS T +++DGV + Sbjct: 181 WITNGSVADVAVVWARTDEG-IRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRL 239 Query: 272 PEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQL 331 P+ LPGA+SLG P CLN AR+GI +G LGA+ CL TA YA R QF P+ QL Sbjct: 240 PDSARLPGATSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQL 299 Query: 332 IQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGG 391 Q+KLADM E G L LGR KD + APE VSL K NN +A++IAR AR +LG Sbjct: 300 TQQKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLGKLNNVREAIEIARTARTVLGA 359 Query: 392 NGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFT 435 +GI+ EY V+RHA NLE+V TYEGT ++H LI+G+A+TG+ AF Sbjct: 360 SGITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQALTGVGAFR 403 >5OL2-C nrPDB Length = 378 Score = 454 bits (1167), Expect = e-128, Method: Composition-based stats. Identities = 118/371 (31%), Positives = 188/371 (50%), Gaps = 8/371 (2%) Query: 65 ILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTIKGYGCAGVSSVAY 123 ++++ + ++ + + P + E F E + +M + G++G P K YG G +V Y Sbjct: 9 QMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGDTVGY 68 Query: 124 GLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN 183 + EL RV +S +SL PIY YG+EEQ+QK+L LA GE LG FGLTEPN Sbjct: 69 IMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPN 128 Query: 184 SGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCIRGFLLE 239 +G+D S +T A + Y LNG+K +ITN+ D++VV A + + I F++E Sbjct: 129 AGTDASGQQTTAVLD--GDEYILNGSKIFITNAIAGDIYVVMAMTDKSKGNKGISAFIVE 186 Query: 240 KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPFGCLNNARYGIA 298 KG G S + K +R SAT +I + +P+EN+L L+ R GIA Sbjct: 187 KGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDGGRIGIA 246 Query: 299 WGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD 358 LG ++ L +Y +R+QFG PL++ Q Q +LADM ++ H Q KD Sbjct: 247 AQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQAAINKD 306 Query: 359 QDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHD 418 K ++ K A+++ +A + GG G + +Y V R + + YEGT + Sbjct: 307 LGKPYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIYEGTSE 366 Query: 419 IHALILGRAIT 429 + +++ + Sbjct: 367 VQRMVISGKLL 377 >4W9U-A nrPDB Length = 395 Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats. Identities = 259/394 (65%), Positives = 307/394 (77%), Gaps = 5/394 (1%) Query: 44 SRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGEL 103 SR F W+DP +LEEQLT DE +IRD+ + + + L+PR+ A E E+ MG+ Sbjct: 3 SRAAFAWEDPFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQA 62 Query: 104 GVLGPT-IKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQ 162 G+LG T + YG A S VAYGL+ARE+ER+DSGYRS MSVQSSLVM+PIYAYGS+EQR+ Sbjct: 63 GLLGVTLPEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRK 122 Query: 163 KYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLF 222 KYLP L GEL+GCFGLTEP++GSDP+ M+TRA + Y L+G+K WI+NSP+AD+F Sbjct: 123 KYLPGLVSGELIGCFGLTEPDAGSDPAGMKTRAE--KIDGGYRLSGSKMWISNSPIADVF 180 Query: 223 VVWARCE--DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA 280 VVWA+ D IRGF+LEKGM+GLSAP+I GK SLRAS TG I+MDGVEV E+ +LP Sbjct: 181 VVWAKSAAHDNAIRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAILPNV 240 Query: 281 SSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADML 340 S L GPFGCLN ARYGI+WGVLGA+E C ARQY LDR QF PLA QL QKKLADM Sbjct: 241 SGLKGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQ 300 Query: 341 TEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHV 400 TEI LG+ A L++GRL D+ K APEM+S++KRNNCGKALDIARQARDM GGNGI EYHV Sbjct: 301 TEIALGIQASLRVGRLFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHV 360 Query: 401 IRHAMNLEAVNTYEGTHDIHALILGRAITGIQAF 434 +RHA NLE VNTYEGTHD+HALILGRA TGIQAF Sbjct: 361 MRHAQNLETVNTYEGTHDVHALILGRAQTGIQAF 394 >2VIG-A nrPDB Length = 391 Score = 447 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 115/386 (29%), Positives = 190/386 (49%), Gaps = 10/386 (2%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 +L ++ T R + ++ L P ++ +F + +MG LG+L + + G AG Sbjct: 5 ELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAG 64 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 + +AY + E+ R + MSV +SL + PI +GS+EQ+Q ++ G+ +GCF Sbjct: 65 LDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCF 124 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCI 233 L+EP +GSD + T A + S+ LNGTK WITN+ A VV+A + + I Sbjct: 125 ALSEPGNGSDAGAASTTA--RAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSI 182 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGGPFGCLNN 292 FL+ GL+ + + K +R S+T +I + +P++++L L+ Sbjct: 183 SAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDM 242 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R GIA LG ++ L A YA +RM FG PL + Q+IQ KLADM + + Sbjct: 243 GRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWR 302 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 LKD K + ++ K A I+ QA +LGG G E RH + Sbjct: 303 AAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEI 362 Query: 413 YEGTHDIHALILGRAITGIQAFTASK 438 YEGT +I L++ + ++++ +++ Sbjct: 363 YEGTSEIQRLVIAGHL--LRSYRSAE 386 >4M9A-A nrPDB Length = 385 Score = 441 bits (1134), Expect = e-124, Method: Composition-based stats. Identities = 112/379 (29%), Positives = 184/379 (48%), Gaps = 8/379 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYG 114 +++ T D+ +I D R +C E L P +R E++++MGELG LG + +G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 + VAY L E+ + + +SV +S+ P+ YG+ EQ++++L LA G+ + Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG--- 231 G F LTEP++GS+ ++ TRA + + LNG+K ++TN A L +V+A + Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELR--DGKWILNGSKQFVTNGARAGLAIVFAMTDPDEGK 186 Query: 232 -CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLP-GASSLGGPFGC 289 + F++ G + + K +RAS T I ++ +P+EN+L L Sbjct: 187 RGLSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSN 246 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L R GIA G + AR+YA +R+QFG P+A +Q I +KLA+M T+I Sbjct: 247 LEGGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLL 306 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 RL+ S K A + A + GG G +Y V RH + Sbjct: 307 THHAARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARI 366 Query: 410 VNTYEGTHDIHALILGRAI 428 YEGT ++ +++ R + Sbjct: 367 TQIYEGTSEVQRMVIARQL 385 >4U83-A nrPDB Length = 382 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 8/376 (2%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGP-TIKGYGCAG 117 LT + IR+ R + QERL P +R F R ++EMG LG LG + +G + Sbjct: 9 LLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGSD 68 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 + VAY L E+ D + +SV SS+ PI +G+E+Q++++LP++A GE +G F Sbjct: 69 LDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGF 128 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG----CI 233 LTEP +GSD S+++TRA + Y ++G+K +IT+ ++ +V+A + I Sbjct: 129 ALTEPQAGSDASALKTRARLD--GDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGI 186 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLP-GASSLGGPFGCLNN 292 F++ G ++ K +S T + + VP EN L L Sbjct: 187 SAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEG 246 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R GIA +G + AR YA +R+ FG P+ +Q + +LADM T I L Sbjct: 247 GRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLH 306 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L++ K S+ K A + A + GG G +Y V R ++ Sbjct: 307 AAALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQI 366 Query: 413 YEGTHDIHALILGRAI 428 YEGT D+ L++ R + Sbjct: 367 YEGTSDVQRLVIARGL 382 >1UKW-A nrPDB Length = 379 Score = 434 bits (1117), Expect = e-122, Method: Composition-based stats. Identities = 114/380 (30%), Positives = 182/380 (47%), Gaps = 9/380 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYG 114 ++ LT ++ ++ R + +E ++P + E +I ++ E+G+L I + YG Sbjct: 1 IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYG 60 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 G+ + ++ EL G + + + S L + P+ G+EEQ++++L L + L Sbjct: 61 GMGLKMLDEVIVGEELAYACMGIYT-IPMASDLGITPVLLAGTEEQKERFLRPLTEKPAL 119 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG--- 231 F L+EP +GSD ++++TRA Y LNGTK WI+N A+ VV+A Sbjct: 120 AAFALSEPGNGSDAAALKTRAIR--QGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRH 177 Query: 232 -CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPFGC 289 + ++E+G G A +I GK RAS T ++ + V+VP EN L Sbjct: 178 KGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQT 237 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 LN R +A G +G + L AR+YA +R FG P+A Q IQ KL DML I Sbjct: 238 LNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMY 297 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 L DQ ++ K A + A QA + GG G E+ V + +++ Sbjct: 298 TYYAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKL 357 Query: 410 VNTYEGTHDIHALILGRAIT 429 YEGT++I LI+ R I Sbjct: 358 NQIYEGTNEIQRLIIARHIL 377 >2A1T-A nrPDB Length = 421 Score = 430 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 106/398 (26%), Positives = 185/398 (46%), Gaps = 12/398 (3%) Query: 41 AKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEM 100 ++ ++ + L + T + + T R + +E ++P ++ + +I Sbjct: 22 SQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRA 81 Query: 101 GELGVLGPTIKG-YGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEE 159 ELG++ I G G+ + L++ EL +G ++A+ +SL PI G+++ Sbjct: 82 WELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEG-NSLGQMPIIIAGNDQ 140 Query: 160 QRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMA 219 Q++KYL ++ + L+ + +TEP +GSD + ++T+A Y +NG K WITN A Sbjct: 141 QKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKA 198 Query: 220 DLFVVWARCED-------GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVP 272 + + + AR + GF++E G+ R + R S T I+ + V+VP Sbjct: 199 NWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVP 258 Query: 273 EENVLPG-ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQL 331 +ENVL G + G + R +A G +G ++ L A +YAL+R FG L +Q Sbjct: 259 KENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQA 318 Query: 332 IQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGG 391 I LA+M ++ L + + D + S+ K A +A A +LGG Sbjct: 319 ISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGG 378 Query: 392 NGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT 429 NG + EY V + + + YEGT I LI+ R Sbjct: 379 NGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHI 416 >2EBA-A nrPDB Length = 385 Score = 428 bits (1101), Expect = e-120, Method: Composition-based stats. Identities = 201/385 (52%), Positives = 252/385 (65%), Gaps = 4/385 (1%) Query: 52 DPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPT-I 110 D LE+ LT +E ++ R + ++ +P I VF +I ELG LGPT Sbjct: 3 DFYALEDLLTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLP 62 Query: 111 KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAK 170 YG AGVSS AYGL+ ELERVDSG RS +SVQSSLVM+PIYAYGSEEQ++++LP+LA+ Sbjct: 63 PEYGGAGVSSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLAR 122 Query: 171 GELLGCFGLTEPNSGSDP-SSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE 229 GE++GCFGLTEP+ GSDP +M+TRA ++ LNGTK WITN +A L V+WA+ E Sbjct: 123 GEMVGCFGLTEPDGGSDPYGNMKTRA--RREGDTWVLNGTKMWITNGNLAHLAVIWAKDE 180 Query: 230 DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC 289 G + GFL+ G A ++ K SLRAS T ++++ V VPE LP A L P C Sbjct: 181 GGEVLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRLPKALGLKAPLSC 240 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L AR+GIAWG +GA E A +A R FG PLA+ QL+Q KLA+ML T GL Sbjct: 241 LTQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGLLL 300 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 +L RLKD+ K P VSL KR N KAL AR ARD+LGG+GI+ EYH IRH +NLE Sbjct: 301 AWRLARLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLET 360 Query: 410 VNTYEGTHDIHALILGRAITGIQAF 434 V TYEGTHD+H L+LGR ITG+ AF Sbjct: 361 VYTYEGTHDVHTLVLGREITGLNAF 385 >1BUC-A nrPDB Length = 383 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 118/383 (30%), Positives = 195/383 (50%), Gaps = 10/383 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKG--- 112 ++ LT + + +++L P + + ++ +E+I E+ LG+ G + Sbjct: 1 MDFNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYG 60 Query: 113 -YGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 171 G G ++Y L EL + D+G +S SL +PI+ +G+E Q++K+L L +G Sbjct: 61 GSGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEG 120 Query: 172 ELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE-- 229 LG FGLTEPN+G+D S +T A N + +YTLNG+K +ITN AD+++V+A + Sbjct: 121 TKLGAFGLTEPNAGTDASGQQTIATKN-DDGTYTLNGSKIFITNGGAADIYIVFAMTDKS 179 Query: 230 --DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGGP 286 + I F+LE G G + + + K + S T ++ V+VP EN+L Sbjct: 180 KGNHGITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIA 239 Query: 287 FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG 346 L+ R G+A LG +E L A +Y+ R+QFG PL + Q I KLADM +I Sbjct: 240 MMTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAA 299 Query: 347 LHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMN 406 + + K + K ++ KR A+ + +A + GG G S+EY V RH + Sbjct: 300 RNLVYKAACKKQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRD 359 Query: 407 LEAVNTYEGTHDIHALILGRAIT 429 + YEGT+++ ++ G A+ Sbjct: 360 AKITQIYEGTNEVQLMVTGGALL 382 >3MDE-A nrPDB Length = 385 Score = 427 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 105/385 (27%), Positives = 178/385 (46%), Gaps = 12/385 (3%) Query: 55 VLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKG-Y 113 +LT + + T R + +E ++P +R + ++ ELG++ I + Sbjct: 1 GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESF 60 Query: 114 GCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGEL 173 G G+ + L+ EL +G ++A+ ++L P+ G+ +Q++KYL ++ + L Sbjct: 61 GGLGLGIIDSCLITEELAYGCTGVQTAIEA-NTLGQVPLIIGGNYQQQKKYLGRMTEEPL 119 Query: 174 LGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED--- 230 + + +TEP +GSD + ++T+A Y +NG K WITN A+ + + AR + Sbjct: 120 MCAYCVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSDPDPK 177 Query: 231 ----GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGG 285 GF++E G+ R + R S T I+ + V VP+ENVL G Sbjct: 178 APASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKI 237 Query: 286 PFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITL 345 G + R +A G +G ++ L A +YAL+R FG LA +Q I LADM ++ L Sbjct: 238 AMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVEL 297 Query: 346 GLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAM 405 + + D + S+ K A +A A + GGNG + EY V + Sbjct: 298 ARLSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMR 357 Query: 406 NLEAVNTYEGTHDIHALILGRAITG 430 + + YEGT I +I+ R G Sbjct: 358 DAKIYQIYEGTAQIQRIIIAREHIG 382 >6FAH-C nrPDB Length = 379 Score = 426 bits (1096), Expect = e-120, Method: Composition-based stats. Identities = 108/377 (28%), Positives = 170/377 (45%), Gaps = 9/377 (2%) Query: 60 LTTDEILIRDTFRTYCQERLMP-RILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAG 117 + +IR R + ++ L + + F +EI+ +M + G G I G +G Sbjct: 3 FSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSG 62 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 ++Y + E RV +S +SL P+ G+EEQ +KYL + G+ F Sbjct: 63 GDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAF 122 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----DGCI 233 LTEP +GSD M T A Y LNG KT+IT +P+ D V++A+ + I Sbjct: 123 ALTEPGAGSDAGGMSTTAV--DMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGI 180 Query: 234 RGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGGPFGCLNN 292 F+++ G+S + + K L AT IIM+ V+VP+EN L + L+ Sbjct: 181 SAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDV 240 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R G+A +G ++ L A +YA +R QFG +A Q I +ADM T++ Sbjct: 241 GRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYN 300 Query: 353 LGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L D K A + S+ K +I +A + GG G EY V R + Sbjct: 301 AASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTI 360 Query: 413 YEGTHDIHALILGRAIT 429 YEGT + +++ + Sbjct: 361 YEGTSQVQQMVISGMLL 377 >4O5M-A nrPDB Length = 390 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 120/379 (31%), Positives = 180/379 (47%), Gaps = 8/379 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPT-IKGYG 114 + L + +RDT R + + R+ P +RN F + E GELGVLG T + YG Sbjct: 9 MNFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYG 68 Query: 115 CAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELL 174 AG+ +A+ + E+ R + + S+L ++ I GS EQR KYLP+L GE + Sbjct: 69 GAGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHV 128 Query: 175 GCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE----D 230 G ++EP +GSD SM+ A Y LNG K WITN P AD+ VV+A+ + Sbjct: 129 GALAMSEPGAGSDVVSMKLAAEKR--GDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGP 186 Query: 231 GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLP-GASSLGGPFGC 289 I F++EKG +G S + K +R S T ++ + EVP EN+L + Sbjct: 187 RGISAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMSG 246 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L+ R +A G LG CL Y +R QF P+ QL+Q KLADM Sbjct: 247 LDYERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAY 306 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 + D+ + + + + A +A QA LGGNG ++Y R + + Sbjct: 307 VYAVAAACDRGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKL 366 Query: 410 VNTYEGTHDIHALILGRAI 428 GT +I +++GR + Sbjct: 367 YEIGAGTSEIRRMLIGREL 385 >1IVH-A nrPDB Length = 394 Score = 423 bits (1088), Expect = e-119, Method: Composition-based stats. Identities = 109/380 (28%), Positives = 181/380 (47%), Gaps = 12/380 (3%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFH--REIISEMGELGVLGPTIK-GYGCA 116 L+ ++ +R T + QE L P+ +R+ F RE ++G LGVLG T YG + Sbjct: 13 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGS 72 Query: 117 GVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGC 176 G+ + + L+ E+ R + S+L ++ + G+E Q++KYLP+L GE +G Sbjct: 73 GLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGA 132 Query: 177 FGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE------D 230 ++EPN+GSD SM+ +A Y LNG K WITN P AD+ +V+A+ + Sbjct: 133 LAMSEPNAGSDVVSMKLKAE--KKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPAS 190 Query: 231 GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLGGPFGC 289 I F++EKGM G S + K +R S T +I + ++P N+L + + Sbjct: 191 RGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSG 250 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 L+ R +A G LG + L Y R FG + QL+Q K+ADM T + Sbjct: 251 LDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQY 310 Query: 350 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 + + D+ + + + + A +A GGNG +++ + R + + Sbjct: 311 VYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKL 370 Query: 410 VNTYEGTHDIHALILGRAIT 429 GT ++ L++GRA Sbjct: 371 YEIGAGTSEVRRLVIGRAFN 390 >3SWO-A nrPDB Length = 399 Score = 419 bits (1077), Expect = e-117, Method: Composition-based stats. Identities = 184/404 (45%), Positives = 248/404 (61%), Gaps = 5/404 (1%) Query: 33 GGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVF 92 G T + +K S + + + L DE I T R + RL P + + Sbjct: 1 GSMTLTAPSKKST--YAPLELFDTDRLLDQDERDIAATVRQFVDTRLKPNVEGWFESATL 58 Query: 93 HREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPI 152 E+ E G LGVLG ++GYGCAG ++V+YGL ELE DSG+RS +SVQ SL M I Sbjct: 59 PSELAKEFGNLGVLGMHLQGYGCAGTNAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSI 118 Query: 153 YAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTW 212 Y YGSEEQ+ ++LP+LA G+ +GCFGLTEP+ GS+P+ M TRA + S+ + LNGTK W Sbjct: 119 YRYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRDGSD--WILNGTKMW 176 Query: 213 ITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVP 272 ITN +AD+ VWA+ +DG IRGFL+ G +A I K SLRAS T +++D V +P Sbjct: 177 ITNGNLADVATVWAQTDDG-IRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLP 235 Query: 273 EENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLI 332 LP A L P CLN AR+GI +G LGA+ L T Y R F PL+ QL Sbjct: 236 ASAQLPLAEGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLT 295 Query: 333 QKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGN 392 Q+KLA+M E+ G+ + LGR+KD + PE +SL K NN +A+ IAR+ R +LGG+ Sbjct: 296 QEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQISLGKLNNVREAIAIARECRTLLGGS 355 Query: 393 GISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTA 436 GI+ EY +RHA NLE+V TYEGT ++H L +G+A+TG AF + Sbjct: 356 GITLEYSPLRHANNLESVLTYEGTSEMHLLSIGKALTGKAAFRS 399 >4KTO-A nrPDB Length = 410 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 121/380 (31%), Positives = 186/380 (48%), Gaps = 8/380 (2%) Query: 55 VLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGY 113 L L + +R + R + ER+ P A+R+ F + EMGELG+LG T + + Sbjct: 28 GLNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAH 87 Query: 114 GCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGEL 173 G AG+ +A+ + E+ R + + S+L ++ I G Q+ +YLP+L GE Sbjct: 88 GGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEH 147 Query: 174 LGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG-- 231 +G ++EP +GSD SM+ +A + Y LNG+K WITN P AD+ VV+A+ + Sbjct: 148 VGALAMSEPGAGSDVVSMKLKA--DKRGDRYVLNGSKMWITNGPDADVLVVYAKTDPAAG 205 Query: 232 --CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFG 288 I FL+EK G SA + K +R S T +I EVPEENVL G + Sbjct: 206 PRGITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLMS 265 Query: 289 CLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLH 348 L+ R ++ G LG CL Y +R QFG P+ QL+Q KLADM + Sbjct: 266 GLDYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAARA 325 Query: 349 ACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLE 408 + D+ + A + + KA +A +A LGGNG +++Y R + + Sbjct: 326 YVYAVAAACDRGETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAK 385 Query: 409 AVNTYEGTHDIHALILGRAI 428 GT +I +++GR + Sbjct: 386 LYEIGAGTSEIRRMLIGREL 405 >2JIF-A nrPDB Length = 404 Score = 416 bits (1070), Expect = e-117, Method: Composition-based stats. Identities = 110/387 (28%), Positives = 190/387 (49%), Gaps = 12/387 (3%) Query: 48 FDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG 107 F PL + T +E++I+ + + + QE++ P + + N + +I + + G++G Sbjct: 20 FQSMAPL---QTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMG 76 Query: 108 PTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLP 166 + YG G S ++ L+ EL +VD+ +Q++L+ I +G+EEQ+ YLP Sbjct: 77 IEVDPEYGGTGASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLP 136 Query: 167 QLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWA 226 QL E +G F L+E +GSD +++TRA + Y LNG+K WI+++ A LF+V A Sbjct: 137 QLTT-EKVGSFCLSEAGAGSDSFALKTRA--DKEGDYYVLNGSKMWISSAEHAGLFLVMA 193 Query: 227 RCEDG----CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-AS 281 + I FL+++ GL + + K LRAS+T + + V+VPE N+L Sbjct: 194 NVDPTIGYKGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGH 253 Query: 282 SLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLT 341 G LN R GIA +LG ++ C Y +R+QFG L Q +Q ++A + T Sbjct: 254 GYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVAT 313 Query: 342 EITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVI 401 ++ RL + K + S+ K A + + +GG G + +Y V Sbjct: 314 QLEAARLLTYNAARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVE 373 Query: 402 RHAMNLEAVNTYEGTHDIHALILGRAI 428 ++ + + YEG +I + + I Sbjct: 374 KYFRDAKIGTIYEGASNIQLNTIAKHI 400 >2IX5-A nrPDB Length = 436 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 143/400 (35%), Positives = 207/400 (51%), Gaps = 3/400 (0%) Query: 39 QLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIIS 98 Q +S D + LT +E IR R ++ + P + F I Sbjct: 34 QATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITP 93 Query: 99 EMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSE 158 ++G +GV G +IKGYGC G+S A + E+ RVD+ + + V SSL M I GSE Sbjct: 94 KLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSE 153 Query: 159 EQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPM 218 Q++KYLP LA+ + C+ LTEP++GSD S + T A + +NG K WI NS Sbjct: 154 AQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTAT--KVEGGWKINGQKRWIGNSTF 211 Query: 219 ADLFVVWAR-CEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL 277 ADL +++AR I GF+++K GL A +I K LR G I++ V VP+E+ L Sbjct: 212 ADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL 271 Query: 278 PGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLA 337 PG +S L +R +AW +G S +Y +R QFG PLA QL Q+KL Sbjct: 272 PGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLV 331 Query: 338 DMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDE 397 ML + +L +L + + P SL K KA + A R++LGGNGI + Sbjct: 332 QMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILAD 391 Query: 398 YHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTAS 437 + V + +LE + TYEGT+DI+ L+ GR +TGI +F + Sbjct: 392 FLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASFKPA 431 >2DVL-A nrPDB Length = 372 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 129/371 (34%), Positives = 191/371 (51%), Gaps = 5/371 (1%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPT-IKGYGCAGV 118 LT ++ L+ D R +E L P +R + + + ELG+LG T + +G G+ Sbjct: 3 LTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 SV + L EL D +SV S L + + +GSE Q+++YL LA+GE +G F Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLL 238 LTEP +GSD S+ RA + LNG K+WIT++ A L+VV AR E G I FL+ Sbjct: 123 LTEPQAGSDAKSL--RAEARRVKGGFVLNGVKSWITSAGHAHLYVVMARTEKG-ISAFLV 179 Query: 239 EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPFGCLNNARYGI 297 EKG GLS R + K L A+ T + ++ V VPEEN+L L L++ R G+ Sbjct: 180 EKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGLDSGRVGV 239 Query: 298 AWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLK 357 A +G + A+ YA +R QFG L +Q I K+ADM +I L+ R K Sbjct: 240 AAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLEAARKK 299 Query: 358 DQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTH 417 D+ + S K A+++ R+A +LGG G +Y V R+ + + YEGT Sbjct: 300 DRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEIYEGTS 359 Query: 418 DIHALILGRAI 428 +I L++ R + Sbjct: 360 EIQRLVIAREL 370 >3PFD-A nrPDB Length = 393 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 95/394 (24%), Positives = 171/394 (43%), Gaps = 10/394 (2%) Query: 43 SSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGE 102 +P QL + I +R+ R ++ + P + F E ++ + Sbjct: 2 PGSMAAWSGNPSFELFQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNS 61 Query: 103 LGVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQR 161 G + + YG G SVA ++ E+ RVD S + + L + GSEE + Sbjct: 62 SGFSAIHVPEEYGGQGADSVATCIVIEEVARVDCS-ASLIPAVNKLGTMGLILRGSEELK 120 Query: 162 QKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADL 221 ++ LP +A GE + + L+E +GSD +SM TRA + + + LNG+K WITN + Sbjct: 121 KQVLPAVASGEAMASYALSEREAGSDAASMRTRAVADGDD--WILNGSKCWITNGGKSTW 178 Query: 222 FVVWARCED----GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL 277 + V A + I F++ K G + + K ++ S T + + +P + ++ Sbjct: 179 YTVMAVTDPDKGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRII 238 Query: 278 PG-ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKL 336 + L++ R I +G ++ L A Y +R QFG P++ NQ +Q L Sbjct: 239 GEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFML 298 Query: 337 ADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLL-KRNNCGKALDIARQARDMLGGNGIS 395 ADM +I ++ + +S K A+++ A + GG G + Sbjct: 299 ADMAMKIEAARLMVYSAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYT 358 Query: 396 DEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT 429 ++ V R + + YEGT+ I +++ RA+ Sbjct: 359 QDFPVERMMRDAKITQIYEGTNQIQRVVMSRALL 392 >2PG0-A nrPDB Length = 385 Score = 393 bits (1009), Expect = e-109, Method: Composition-based stats. Identities = 106/378 (28%), Positives = 169/378 (44%), Gaps = 13/378 (3%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGV 118 L + + R FR + ++ P + + R ++MGE G L P + + YG Sbjct: 10 LREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNA 69 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 ++ ELE+V S + + + +V I +YG+EEQ+QK+LP+ GEL+ Sbjct: 70 DFAYSVVINEELEKVGSSL-VGIGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIA 128 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG------C 232 +TEP +GSD +++ T A Y +NG KT+ITN ADL VV + + Sbjct: 129 MTEPGAGSDLANISTTAV--KDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPPHRG 186 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGG--PFGCL 290 I ++E+ G + R K L A T + +VP N+L G G L Sbjct: 187 ISLLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLL-GEEGKGFYYLMEKL 245 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 R +A A+E +QY R FG ++ Q +Q +LA+M TEI LG Sbjct: 246 QQERLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFV 305 Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 ++ K VS+ K A +A +A + GG G +EY + R ++ Sbjct: 306 DRVIEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVS 365 Query: 411 NTYEGTHDIHALILGRAI 428 Y GT+++ I+ R + Sbjct: 366 AIYAGTNEMMKTIIARQL 383 >1RX0-A nrPDB Length = 393 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 100/377 (26%), Positives = 173/377 (45%), Gaps = 11/377 (2%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGV 118 L ++ + + + P + ++ E+F +++ + +LG G I+ G +G+ Sbjct: 19 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 78 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 S + ++ L + + +S+ + + I ++G+EEQR K+ P L E + Sbjct: 79 SRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 137 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC---EDGCIRG 235 LTEP SGSD +S+ T A Y LNG+K +I+ + +D++VV R I Sbjct: 138 LTEPGSGSDAASLLTSA--KKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 195 Query: 236 FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNNA 293 ++EKG GLS + + K + T +I + VP N + G+ G LN Sbjct: 196 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRI-GSEGQGFLIAVRGLNGG 254 Query: 294 RYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQL 353 R IA LGA+ + R + R QFG PLA NQ +Q LADM T + Sbjct: 255 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 314 Query: 354 G-RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 412 L+++ K A + S+ K + I QA M GG G +Y V ++ + Sbjct: 315 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 374 Query: 413 YEGTHDIHALILGRAIT 429 EG++++ +++ R++ Sbjct: 375 LEGSNEVMRILISRSLL 391 >4IV6-A nrPDB Length = 388 Score = 388 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 102/379 (26%), Positives = 166/379 (43%), Gaps = 13/379 (3%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTIKGYGCAGV 118 LT +E I T + ++++ P + + E+I M E+G+ G + YG V Sbjct: 7 LTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAV 66 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 S Y +A EL R AM + +V + +G+EEQ+QKYLP++A GEL Sbjct: 67 SMPCYVQVAEELARGWMSLAGAMGGHT-VVSKLLLLFGTEEQKQKYLPRMATGELRATMA 125 Query: 179 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED------GC 232 LTEP GSD +M T A + + Y +NG+KTWI+N+ +DL + + + Sbjct: 126 LTEPGGGSDLQAMRTVARRDGDD--YVINGSKTWISNARRSDLVALMCKTDPDAQPAHKG 183 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGP--FGCL 290 + L+EK + G R K + + + VP ++L G L Sbjct: 184 VSILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGL 242 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 R +A G + A +Y+ +R FG P+ ++Q + LADM T++ Sbjct: 243 EVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLL 302 Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 L D + + K A+ IA A + GG G S EY V R+ + + Sbjct: 303 LSAAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPLM 362 Query: 411 NTYEGTHDIHALILGRAIT 429 EGT++I ++ + + Sbjct: 363 IVGEGTNEIQRNVIAKQLV 381 >2Z1Q-A nrPDB Length = 577 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 120/388 (30%), Positives = 190/388 (48%), Gaps = 18/388 (4%) Query: 54 LVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNE-VFHREIISEMGELGVLGPTI-K 111 + E I T RT+ + ++P + E + ++ + GELG+L + + Sbjct: 22 VYTPEDFDESVKEIARTTRTFVEREVLPLLERMEHGELELNVPLMRKAGELGLLAIDVPE 81 Query: 112 GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 171 YG + V ++A EL G+ +S+ P+ +G+EEQ++KYLP+LA G Sbjct: 82 EYGGLDLPKVISTVVAEELS-GSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASG 140 Query: 172 ELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG 231 E + + LTEP SGSD + +TRA + K Y LNG K WI+N+ A LF V+A+ + Sbjct: 141 EWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAKVDGE 200 Query: 232 CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGCL 290 FL+E+ GLS + K ++AS+T +I++ V+VP ENVL F L Sbjct: 201 HFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGKGHKIAFNVL 260 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 N RY + G +G ++ L + QYA R+QFG P+ R LIQ+KL +M + I A Sbjct: 261 NVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAESAV 320 Query: 351 LQLGRLKDQ---DKAAPE-----------MVSLLKRNNCGKALDIARQARDMLGGNGISD 396 + L D+ K PE S++K + + + GG G S Sbjct: 321 YRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGYSQ 380 Query: 397 EYHVIRHAMNLEAVNTYEGTHDIHALIL 424 EY + R + +EGT++I+ L++ Sbjct: 381 EYPIERAYRDARINRIFEGTNEINRLLI 408 >3NF4-A nrPDB Length = 387 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 101/382 (26%), Positives = 180/382 (47%), Gaps = 8/382 (2%) Query: 53 PLVLEEQLTTDEI-LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTI 110 P+ ++ L + E + + R + L P + ++E + + ++G G+L P Sbjct: 8 PMAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQP 67 Query: 111 KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAK 170 + +G G Y + E+ + A+SV SL HP+ +G+EEQ++++LP + Sbjct: 68 EEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVH-SLSSHPLLVFGTEEQKKRWLPGMLS 126 Query: 171 GELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED 230 GE +G + L+EP +GSD +++ A ++ Y +NG+K+WIT+ AD + ++AR + Sbjct: 127 GEQIGAYSLSEPQAGSDAAALRCAAT--PTDGGYVINGSKSWITHGGKADFYTLFARTGE 184 Query: 231 G--CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-SSLGGPF 287 G + FL+ GLS + + K L A T D + + + L F Sbjct: 185 GSRGVSCFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAF 244 Query: 288 GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGL 347 L++ R GIA G ++ L A YA +R FG + +Q + LADM + Sbjct: 245 SALDSGRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATAR 304 Query: 348 HACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNL 407 L R +DQ + + S+ K A+ + A + GG G + +Y V R+ Sbjct: 305 ATYLDAARRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREA 364 Query: 408 EAVNTYEGTHDIHALILGRAIT 429 + + +EGT+ I L++ R +T Sbjct: 365 KIMQIFEGTNQIQRLVIARGLT 386 >3OWA-A nrPDB Length = 597 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 118/399 (29%), Positives = 186/399 (46%), Gaps = 27/399 (6%) Query: 50 WQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHRE--IISEMGELGVLG 107 D + E +++ +I T + ++P + F R ++ E GELG+LG Sbjct: 23 TIDQVFTPEDFSSEHKMIAKTTEDFIVNEVLPEL-EYLEQHEFDRSVRLLKEAGELGLLG 81 Query: 108 PTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLP 166 + + YG G+ V+ L+A + R G+ + PI +G+EEQ++KYLP Sbjct: 82 ADVPEEYGGIGLDKVSSALIAEKFSRA-GGFAITHGAHVGIGSLPIVLFGNEEQKKKYLP 140 Query: 167 QLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWA 226 LA GE L + LTEP SGSD +T A N+ Y LNG K WITNS AD+F+V+A Sbjct: 141 LLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYA 200 Query: 227 RCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGG- 285 + + F++EK G+S + K ++ S+T +I++ VP+EN+L G G Sbjct: 201 KIDGEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLL-GEIGKGHI 259 Query: 286 -PFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 344 F LN RY + G +G+++ + + QYA R QF P+AR LIQ+KLA+M + Sbjct: 260 IAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTY 319 Query: 345 LGLHACLQLGRLKDQDKAAPE-------------------MVSLLKRNNCGKALDIARQA 385 + + L + + SL K + Sbjct: 320 AAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEG 379 Query: 386 RDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALIL 424 + GG G EY + R + +EGT++I+ LI+ Sbjct: 380 VQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIV 418 >3MPI-A nrPDB Length = 397 Score = 378 bits (972), Expect = e-105, Method: Composition-based stats. Identities = 108/388 (27%), Positives = 186/388 (47%), Gaps = 14/388 (3%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFH-REIISEMGELGVLGPTI-KGY 113 ++ L+ + +++ R + ++++P + F E + MGELG G I + Y Sbjct: 1 MDFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEY 60 Query: 114 GCAGVSS--VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 171 G G+ +A ++ E+ R S R ++++ + I YGSE ++KY+P+L+ Sbjct: 61 GGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSA 120 Query: 172 ELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG 231 E LG FG+TEP++GSD +M + A + LNG+KTWI+N+ AD+ + +A + Sbjct: 121 EFLGGFGITEPDAGSDVMAMSSTAE--DKGDHWLLNGSKTWISNAAQADVLIYYAYTDKA 178 Query: 232 ----CIRGFLL-EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGG 285 + F++ + G+ ++ K AS TG + +D V+VP+EN+L Sbjct: 179 AGSRGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGARI 237 Query: 286 PFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITL 345 FG LN+ R A G +G ++ CL A +Y +R QFG P+ Q+ Q +A M E+ Sbjct: 238 VFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVEA 297 Query: 346 GLHACLQLGRLKDQDK-AAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 404 + KD+ + V++ K A A +LG G S EY V R Sbjct: 298 ARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARFY 357 Query: 405 MNLEAVNTYEGTHDIHALILGRAITGIQ 432 + EG+ +I +I+ G++ Sbjct: 358 RDAPTYYMVEGSANICKMIIALDQLGVR 385 >4IRN-A nrPDB Length = 416 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 93/398 (23%), Positives = 168/398 (42%), Gaps = 20/398 (5%) Query: 39 QLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIIS 98 Q+ + S +F W + +I R + Q+ L+ ++ ++ E+F+R+ Sbjct: 29 QMGRGSEFDFAW----------NSQQIQFRKKVIQFAQQSLISDLIKNDKEEIFNRDAWQ 78 Query: 99 EMGELGVLG-PTIKGYGCAGVSSVAYGLLARELERVD--SGYRSAMSVQSSLVMHPIYAY 155 + E GV G P YG + + + L +G AM+ P+ + Sbjct: 79 KCSEFGVHGWPIPARYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTF 138 Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITN 215 G+EEQ++KYLP L +G + TEP +GSD S++T A Y LNG K ++TN Sbjct: 139 GTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQ--KDGDKYILNGYKHYVTN 196 Query: 216 SPMADLFVVWARCED----GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEV 271 +ADLF+++A + + F++EK GL + K +R + + ++ EV Sbjct: 197 GTIADLFIIFATIDPSLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEV 256 Query: 272 PEENVLPGA-SSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQ 330 N L + L + R I +G E L + +YA QFG + + Q Sbjct: 257 SAANRLGEEGTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKFQ 316 Query: 331 LIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLG 390 L+ KL +M + ++ +K+ + A S+ + +A ++ G Sbjct: 317 LVANKLVEMKLRLENAKAYLYKVAWMKENKQMALLEASMANLYISEAWVQSCLEAIEIHG 376 Query: 391 GNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 G + R + A Y GT +I +++ + + Sbjct: 377 AYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAKFL 414 >2CX9-A nrPDB Length = 387 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 111/378 (29%), Positives = 175/378 (46%), Gaps = 12/378 (3%) Query: 62 TDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKG-YGCAGVSS 120 +E + FR + + + P +R F +++ ++ E GV G + YG AG+S+ Sbjct: 9 AEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAYGGAGLST 68 Query: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180 + + + D ++ +SL I GSE Q++ +LP+LA GE LG +GLT Sbjct: 69 RLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLT 128 Query: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED--------GC 232 EP SGSD ++++T+A + LNGTK +IT +A ++VV AR + Sbjct: 129 EPGSGSDAAALKTKAE--KVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSPERKHQG 186 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLP-GASSLGGPFGCLN 291 I F + RGL R + K L AS T +I++ + VPEE +L L+ Sbjct: 187 ISAFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGFYDVLRVLD 246 Query: 292 NARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACL 351 R GIA +G + L A YA R FG P+A + + KLA+ TE+ L Sbjct: 247 GGRIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARLLYL 306 Query: 352 QLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVN 411 + LKD + + K A+ +A +LGG G +Y V R+ + Sbjct: 307 KAAELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWRDARLTR 366 Query: 412 TYEGTHDIHALILGRAIT 429 EGT +I L++ R + Sbjct: 367 IGEGTSEILKLVIARRLL 384 >6ES9-A nrPDB Length = 551 Score = 353 bits (906), Expect = 9e-98, Method: Composition-based stats. Identities = 113/388 (29%), Positives = 174/388 (44%), Gaps = 22/388 (5%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLAN-RNEVFHREIISEMGELGVLGPTI-KGYGCAG 117 L D +IRD FR Y +ER++P + ++++ EII E+ ELGV G TI + +G G Sbjct: 167 LDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLG 226 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 177 +S + ++ EL R G S + +S + I G+E Q+ K+LP LA GE+L Sbjct: 227 LSKASMVVVTEELSRGYIGVGS-LGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTA 285 Query: 178 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG-----C 232 TEPN+GSD S+ TRA + + + + G KTWIT++ + + AR + Sbjct: 286 VFTEPNTGSDLGSLRTRAVRDGED--WVVTGNKTWITHAQRTHVMTLLARTDPETTDWRG 343 Query: 233 IRGFLLEK---------GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSL 283 + FL EK G++ I+ R + DG + EN+L G Sbjct: 344 LSMFLAEKEPGTDDDPFPTPGMTGGEIE-VLGYRGMKEYELGFDGFRIKGENLLGGEPGR 402 Query: 284 GGP--FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLT 341 G +AR A +G ++ +YA+DR QFG L + KLA M Sbjct: 403 GFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAV 462 Query: 342 EITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVI 401 EI + KD + + K A A A + GGNG + EY + Sbjct: 463 EIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAIS 522 Query: 402 RHAMNLEAVNTYEGTHDIHALILGRAIT 429 R + +N +EG +I A ++ R + Sbjct: 523 RVLCDARILNIFEGAAEIQAQVIARRLL 550 >3B96-A nrPDB Length = 587 Score = 351 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 114/401 (28%), Positives = 180/401 (44%), Gaps = 22/401 (5%) Query: 53 PLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK- 111 P VL E+ T + + + +E P + E+ + ELG G + Sbjct: 23 PSVLNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPS 80 Query: 112 GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 171 G G+ + Y L + D G + S+ I +G++ Q++KYLP+LA G Sbjct: 81 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 140 Query: 172 ELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC--- 228 E + F LTEP+SGSD +S+ T A + K YTLNG+K WI+N +AD+F V+A+ Sbjct: 141 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 200 Query: 229 ------EDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-AS 281 I F++E+G G++ + K ++AS T + DGV VP ENVL S Sbjct: 201 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 260 Query: 282 SLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLT 341 LNN R+G+A + G + A +A +R QFG + LIQ+KLA M+ Sbjct: 261 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 320 Query: 342 EITLGLHACLQLGRLKDQDK-AAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHV 400 + + DQ ++ K A + + ++GG G E V Sbjct: 321 LQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV 380 Query: 401 IRHAMNLEAVNTYEGTHDIHALILG--------RAITGIQA 433 R +L +EGT+DI L + + ++G+ + Sbjct: 381 ERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 421 >3R7K-A nrPDB Length = 403 Score = 345 bits (886), Expect = 2e-95, Method: Composition-based stats. Identities = 89/403 (22%), Positives = 167/403 (41%), Gaps = 11/403 (2%) Query: 33 GGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVF 92 G T + +S + + + E T + + R++ + + P++ Sbjct: 3 GSMTDAGTTTASE-DGAARFVVAPEAWTTPERRALSQMARSFVEREIAPKLAEWEHVGEI 61 Query: 93 HREIISEMGELGVLGPTI-KGYGCAGVSSVAYGLLAREL--ERVDSGYRSAMSVQSSLVM 149 R++ E+G+LG + G +G +++ L+ + +G +A+ + + Sbjct: 62 PRDLHLNAAEVGLLGIGFPEEVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTHG-IAL 120 Query: 150 HPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGT 209 I A GS+ ++Y+ G+++G G+TEP +GSD +++ TRA +Y +NG Sbjct: 121 PHIAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDVANLRTRAVR--EGDTYVVNGA 178 Query: 210 KTWITNSPMADLFVVWARCED---GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIM 266 KT+IT+ AD R G + +++K G R K R S T + Sbjct: 179 KTFITSGVRADFVTTAVRTGGPGYGGVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSF 238 Query: 267 DGVEVPEENVLPGA-SSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVP 325 V VP +N++ S R GIA + L A+ +A +R FG P Sbjct: 239 VDVRVPADNLVGAENSGFLQIMQQFQAERLGIAVQAYATAGRALDLAKSWARERETFGRP 298 Query: 326 LARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQA 385 L Q+I+ KLA+M ++ + + + + VS+ K + +A Sbjct: 299 LTGRQIIRHKLAEMARQVDVACTYTRAVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEA 358 Query: 386 RDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 + GG G E + RH + + GT++I ++ + I Sbjct: 359 VQIFGGMGYMRESEIERHYRDCRILGIGGGTNEIMNEVIAKRI 401 >5ZW7-A nrPDB Length = 402 Score = 333 bits (855), Expect = 8e-92, Method: Composition-based stats. Identities = 87/381 (22%), Positives = 164/381 (43%), Gaps = 10/381 (2%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGV-LGPTIKGYG 114 ++ L+ + I ++ + + L ++ E+ + G GP +G Sbjct: 1 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFG 60 Query: 115 CAGVSSVAYGLLARELERV--DSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGE 172 + + ++ L+ L + D G ++ + P+Y +GS E + KYL L G+ Sbjct: 61 GSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGK 120 Query: 173 LLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG- 231 L+ TEP++GSD +M+ A Y LNG K +ITN+P+AD+F+++A+ Sbjct: 121 LIAANAATEPDAGSDIYNMQATAQ--PCEGGYILNGKKIFITNAPIADVFIIYAKTNPDH 178 Query: 232 ---CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPF- 287 + FL+EKG GL+ + K L I+ + + +P+ + + G F Sbjct: 179 GFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFH 238 Query: 288 GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGL 347 + + ++ +G L T +YA R QFG + + Q + ++ DM + Sbjct: 239 DSMIWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCR 298 Query: 348 HACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNL 407 + DQ + A +++ K A+ A GG + E ++RH +N+ Sbjct: 299 LMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNM 358 Query: 408 EAVNTYEGTHDIHALILGRAI 428 + GT+DI I+ R + Sbjct: 359 IPSRIFSGTNDIQKEIIARKL 379 >3P4T-A nrPDB Length = 403 Score = 330 bits (846), Expect = 8e-91, Method: Composition-based stats. Identities = 93/390 (23%), Positives = 148/390 (37%), Gaps = 11/390 (2%) Query: 47 EFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVL 106 E Q P + T + +R T R + + ++P R RE+ + ELG+L Sbjct: 13 EAQTQGPGSMSIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLL 72 Query: 107 GPTIKGYGCAGVSSVAY-GLLARELERVDS--GYRSAMSVQSSLVMHPIYAYGSEEQRQK 163 G A ++ E+ S G +++ V H I A G + Sbjct: 73 GAGFPEDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMI-ASGDQRLIDT 131 Query: 164 YLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFV 223 Y+ +GE +G +TEP GSD + TRA + Y +NG KT+IT+ AD V Sbjct: 132 YVRPTLRGEKIGALAITEPGGGSDVGHLRTRA--DLDGDHYVINGAKTYITSGVRADYVV 189 Query: 224 VWARCED---GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA 280 AR G + +++KG G R K R+S T + V VP N++ Sbjct: 190 TAARTGGPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSE 249 Query: 281 -SSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADM 339 + R G+A ++ CL ++ +R FG PL Q +Q LA M Sbjct: 250 NTGFAQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGM 309 Query: 340 LTEITLGLHACLQLGRLKDQDKAAP-EMVSLLKRNNCGKALDIARQARDMLGGNGISDEY 398 I + + + + V K +A QA + GG G E Sbjct: 310 ARRIDVARVYTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAES 369 Query: 399 HVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 V R ++ + GT +I + + + Sbjct: 370 EVERQYRDMRILGIGGGTTEILTSLAAKTL 399 >5IDU-A nrPDB Length = 410 Score = 321 bits (823), Expect = 4e-88, Method: Composition-based stats. Identities = 97/383 (25%), Positives = 157/383 (40%), Gaps = 16/383 (4%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVL--GPTIKGYGCAG 117 + + + L + + + R+++ +GE G L G YG G Sbjct: 26 FEARHRELAAGIEAWATQHLA--CVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHG 83 Query: 118 --VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLG 175 + + A LL L D A+++Q L I G+ EQ+ +YLP+++KGE + Sbjct: 84 DTIDTRAVCLLRETLANHDGLADFALAMQG-LGSGAITLAGTHEQKIRYLPRVSKGEAIA 142 Query: 176 CFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG---- 231 F L+EP++GSD ++M +A + Y ++G KTWI+N +AD +VV+AR + Sbjct: 143 AFALSEPDAGSDVAAMSLQA--RAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGAR 200 Query: 232 CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGCL 290 I F+++ GL + + D VP +L L Sbjct: 201 GISAFIVDADTPGLQIAERIDVIAPH--PLARLHFDSARVPRSQMLGAPGEGFKIAMRTL 258 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 + R +A LG + L A R FG L QL Q KLA M I Sbjct: 259 DVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLV 318 Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 + L+DQ + ++ K + A + A + GG G+ V R + A+ Sbjct: 319 YRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRAL 378 Query: 411 NTYEGTHDIHALILGRAITGIQA 433 YEG ++ LI+GR + A Sbjct: 379 RIYEGATEVQQLIVGRDLLKAHA 401 >5AHS-A nrPDB Length = 401 Score = 303 bits (775), Expect = 2e-82, Method: Composition-based stats. Identities = 85/389 (21%), Positives = 154/389 (39%), Gaps = 22/389 (5%) Query: 59 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAG 117 +LT ++ ++ R Q + + E + + ++++ + G +G + G G Sbjct: 3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRG 62 Query: 118 VSSVAYGLLARELERVDSGYRSAMSVQSSLV-MHPIYAYGSEEQRQKYLPQLAKGELLGC 176 +S++ ++ E+ + + ++V S+L + I YGSEEQ + + G+ Sbjct: 63 LSTLDTVIVIEEMAKACATMG-RITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDK-PA 120 Query: 177 FGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC-EDG---C 232 ++EPN+GS S M TRA + + Y LNG K WIT ++ L +++AR +DG Sbjct: 121 ICISEPNAGSAASEMTTRA--DKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQG 178 Query: 233 IRGFLL---EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC 289 I F+ + G GL R +R + +++ + ++ L F Sbjct: 179 IGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAA 238 Query: 290 L----NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITL 345 L N R G LG ++ Y R QFG PLA Q +Q +ADM ++ Sbjct: 239 LMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEA 298 Query: 346 GLHACLQLGRLKDQDKAAPEM--VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRH 403 + P++ + K A + A G +G + RH Sbjct: 299 ARLMLRSAAV---SGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERH 355 Query: 404 AMNLEAVNTYEGTHDIHALILGRAITGIQ 432 + GT I + I ++ Sbjct: 356 VRDARMFTIAGGTAQILRTQVASKILDMK 384 >6CY8-B nrPDB Length = 380 Score = 299 bits (766), Expect = 2e-81, Method: Composition-based stats. Identities = 81/379 (21%), Positives = 151/379 (39%), Gaps = 16/379 (4%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLG-PTIKGYG 114 + + T ++ + + + +E P + F R+ + +G+ G G P + Y Sbjct: 1 MNFEWTHEQAELFEHALRFGKELSAPL----QEDNGFPRDNWNALGDFGYFGLPIPEKYA 56 Query: 115 --CAGVSSVAYGLLARELER--VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAK 170 +G + + L + D+G A + + PI +GSE + + LP LA Sbjct: 57 KDGSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLAT 116 Query: 171 GELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED 230 G + ++E ++GSD S++ T A Y LNG K+++TN +AD +VV+A Sbjct: 117 GRKIAANAISEASAGSDISNLATTAQ--KEGDYYVLNGGKSYVTNGSIADYYVVYATTNK 174 Query: 231 G----CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGP 286 F++ + G+S K LR++ + D + ++ L Sbjct: 175 KHGYLGQTAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGARI 234 Query: 287 FG-CLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITL 345 F ++ R + +GA + L+ +YA RMQ ++R Q + ++ADM + Sbjct: 235 FAASMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLES 294 Query: 346 GLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAM 405 K QD + V++ K + + + G G DE V Sbjct: 295 ARLMLYYAAWQKSQDVDNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVNNSIK 354 Query: 406 NLEAVNTYEGTHDIHALIL 424 + + GT DI ++ Sbjct: 355 DALGSVLFSGTSDIQRELI 373 >5JSC-A nrPDB Length = 410 Score = 297 bits (761), Expect = 5e-81, Method: Composition-based stats. Identities = 92/379 (24%), Positives = 148/379 (39%), Gaps = 16/379 (4%) Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAG-- 117 + +C+ L + R ++ E+G G L + G G Sbjct: 26 FEPRHRELAAGIEAWCRANLA--HEDHEDVDATCRRLVRELGAAGWLKYGVGGVAYGGHG 83 Query: 118 --VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLG 175 + + A LL L + A+++Q L I G+ EQ+ +YLP++A G + Sbjct: 84 DTIDTRAVCLLRETLAKHSGLADFALAMQG-LGSGAISLGGTHEQKTRYLPRVANGTAIA 142 Query: 176 CFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG---- 231 F L+EP +GSD ++M A +Y L+G KTWI+N +AD +VV+AR + Sbjct: 143 AFALSEPEAGSDVAAMTLSA--REDGDAYVLDGDKTWISNGGIADFYVVFARTGEAPGAR 200 Query: 232 CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGCL 290 I F+++ GL + + G VP +L L Sbjct: 201 GISAFVVDADTPGLEIAERIDVIAPH--PLARLHFAGARVPRSQMLGAPGEGFKLAMRTL 258 Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350 + R +A LG + + A R FG L QL Q KLA M I Sbjct: 259 DIFRTSVAAASLGFARHAMAEGVARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLV 318 Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410 + L+DQ + ++ K + A + A + GG G+ V + A+ Sbjct: 319 YRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRAL 378 Query: 411 NTYEGTHDIHALILGRAIT 429 YEG ++ LI+GR + Sbjct: 379 RIYEGATEVQQLIVGRDLL 397 >4RM7-A nrPDB Length = 391 Score = 268 bits (685), Expect = 3e-72, Method: Composition-based stats. Identities = 90/394 (22%), Positives = 154/394 (39%), Gaps = 18/394 (4%) Query: 55 VLEEQLTTDEILIRDTFRTYCQERLMP-RILLANRNEVFHREIISEMGELGVLG-PTIKG 112 + + L+ DE + + R Y ++ P I +++ E++ +L G I Sbjct: 3 AMYDGLSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHR 62 Query: 113 YGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIY-AYGSEEQRQKYLPQLA-K 170 A L+ EL R+ + Q+ L+ I A+ S Q + + Sbjct: 63 RNHRTYDLFAQVLVIEELSRISGAC---LPFQNDLLQLQILEAFASSAQTSPFRTEYQDT 119 Query: 171 GELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED 230 G L ++EP +GSD SM T H + +NGTK ++ N A +V A + Sbjct: 120 GRLSYALAISEPEAGSDTRSMRT--HVTREGDTLVMNGTKMFVNNGEYAPALLVSAYDKT 177 Query: 231 GC-----IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGAS-SLG 284 G +++ + G+ A + K + D VEV E L G+S Sbjct: 178 GDDGEPEFSFWMVPRSAAGIYA-YPEQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFS 236 Query: 285 GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEIT 344 + L R LG ++ + A +A R FG +A Q +Q KL +M ++T Sbjct: 237 QLYSLLEYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLT 296 Query: 345 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 404 + R D+ + V+L+K A ++A A +LGG G E V Sbjct: 297 NMRNLVYGAAREYDRGEHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIW 356 Query: 405 MNLEAVNTYEGTHDIHALILGRAITGIQAFTASK 438 + +GT ++ +I I ++ + ASK Sbjct: 357 QDCRGYQFADGTDEVMVVIAAPLI--LEQYKASK 388 >4HR3-A nrPDB Length = 415 Score = 267 bits (682), Expect = 9e-72, Method: Composition-based stats. Identities = 84/409 (20%), Positives = 154/409 (37%), Gaps = 37/409 (9%) Query: 52 DPLVLEEQLTTDEILIRDTFRTYCQERLMPR--ILLANRNEVF-------------HREI 96 P ++ + + R + +MP +LA+ +E+ E+ Sbjct: 1 GPGSMDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPEL 60 Query: 97 ---ISEMGELGVLGPTIK--GYGCAGVSSVAYGLLARELERVDSGYRSA-MSVQSSLVMH 150 ++ G+ + G G+S+ Y LA ++ R + S M Sbjct: 61 DSLKAKARAAGLWNLFLPDPELGG-GLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNME 119 Query: 151 PIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLNGT 209 ++ YGS+EQ++ +L L +G++ F +TEP+ + SD ++M A +NG Sbjct: 120 VLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVV--EGDEVVINGR 177 Query: 210 KTWITNSPMAD--LFVVWARCEDGCI-----RGFLLEKGMRGLSAPRIQGKFSL--RASA 260 K W T D + + + L+ G++ R+ Sbjct: 178 KWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGG 237 Query: 261 TGMIIMDGVEVPEENVLPG-ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDR 319 G++ D V +P + + G G L R A ++G +E L A + LDR Sbjct: 238 HGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDR 297 Query: 320 MQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQ--DKAAPEMVSLLKRNNCGK 377 FG PL ++++AD I L L D A VS +K Sbjct: 298 TAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNM 357 Query: 378 ALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 A + A + GG G+S+++ + +N A+ +G ++H ++ R Sbjct: 358 AQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVAR 406 >2WBI-A nrPDB Length = 428 Score = 263 bits (673), Expect = 1e-70, Method: Composition-based stats. Identities = 76/396 (19%), Positives = 150/396 (37%), Gaps = 37/396 (9%) Query: 61 TTDEILIRDTFRTYCQERLMPRILLANRNEVFHRE-----------IISEMGEL----GV 105 T + + + ++ ++P E + + +I ++ E+ G+ Sbjct: 24 TRKGQEVLIKVKHFMKQHILP--AEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGL 81 Query: 106 LGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSA-MSVQSSLVMHPIYAYGSEEQRQKY 164 + +G+S V Y L+A E + + M ++ YGSEEQ++++ Sbjct: 82 WNLFLPAV--SGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQW 139 Query: 165 LPQLAKGELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS--PMADL 221 L L +G + CF +TEP+ + SD +++E + SY +NG K W + + P + Sbjct: 140 LEPLLQGNITSCFCMTEPDVASSDATNIECSIQRD--EDSYVINGKKWWSSGAGNPKCKI 197 Query: 222 FVVWARCEDGCIR------GFLLEKGMRGLSAPRIQGKFSLRASATG---MIIMDGVEVP 272 +V R ++ + L+ G+ R F + G I + V VP Sbjct: 198 AIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVP 257 Query: 273 EENVLPGA-SSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQL 331 N++ G G L R +G +E L + A R+ F L +++ Sbjct: 258 ATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEV 317 Query: 332 IQKKLADMLTEITLGLHACLQLGRLKDQ--DKAAPEMVSLLKRNNCGKALDIARQARDML 389 + +A+ I L+ D A + ++++K I A + Sbjct: 318 VAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVC 377 Query: 390 GGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILG 425 GG G+S +Y + + +G ++H + Sbjct: 378 GGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIA 413 >1R2J-A nrPDB Length = 366 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 87/357 (24%), Positives = 146/357 (40%), Gaps = 10/357 (2%) Query: 82 RILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARELERVDSGYRSA 140 R + + R+++ +G G+L + +G G+ S G + + S RS Sbjct: 15 RAAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSV 74 Query: 141 MSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSS 200 M+ Q + + G QR +L +L G L G +E +GSD S+M TR + Sbjct: 75 MTSQG-MAAWTVQRLGDAGQRATFLKELTSG-KLAAVGFSERQAGSDLSAMRTRVRLD-- 130 Query: 201 NKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASA 260 + ++G K W T + AD VV+ EDG ++ G+ R+ RA+ Sbjct: 131 GDTAVVDGHKVWTTAAAYADHLVVFGLQEDGSGAVVVVPADTPGVRVERVPKPSGCRAAG 190 Query: 261 TGMIIMDGVEVPEENVLPGASSLGGPF---GCLNNARYGIAWGVLGASEFCLHTARQYAL 317 + +D V VP VL G+ P L R +AWG +G C A +A Sbjct: 191 HADLHLDQVRVPAGAVLAGS-GASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAHAR 249 Query: 318 DRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSL-LKRNNCG 376 R QFG PL +QL+ +AD+ T + C D+ ++ K Sbjct: 250 TREQFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVAAE 309 Query: 377 KALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQA 433 +A A A +L G + + V R + + + EG+ ++ ++L + + A Sbjct: 310 RAAAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHALALPA 366 >5YS9-A nrPDB Length = 708 Score = 240 bits (613), Expect = 9e-64, Method: Composition-based stats. Identities = 84/357 (23%), Positives = 127/357 (35%), Gaps = 60/357 (16%) Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAK--GELLGCFGLTEPNSGSDPSS 190 VD G R + V + L M I G++EQ ++ + A GCF +TE GS+ + Sbjct: 114 VDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHGSNVAG 173 Query: 191 METRAHYNSSNKSYTLN-----GTKTWITNSPM-ADLFVVWARC----EDGCIRGFLLE- 239 +ET A Y + +N TK WI + A +AR +D ++ F+++ Sbjct: 174 LETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVVQL 233 Query: 240 ------KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL---PGASSLGG----- 285 M G++ I K A G I V +P +N+L SS G Sbjct: 234 RDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPP 293 Query: 286 ----PFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGV----------------- 324 +G L R + S+ + A +YA R QFG Sbjct: 294 LAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQR 353 Query: 325 ---PLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSL---------LKR 372 PL K AD LQ KD+ +V L LK Sbjct: 354 RLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGLKA 413 Query: 373 NNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT 429 +I Q R GG+G S + + T+EG +++ L +GR + Sbjct: 414 FTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGLI 470 >5Y9D-A nrPDB Length = 709 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 70/363 (19%), Positives = 125/363 (34%), Gaps = 65/363 (17%) Query: 131 ERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQ--LAKGELLGCFGLTEPNSGSDP 188 VD R+ +S+ ++L + I G+ EQ + ++ + +A + GCF +TE GS+ Sbjct: 118 GMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNL 177 Query: 189 SSMETRAHYNSSNKSYTLN-----GTKTWITNSPM-ADLFVVWARC----EDGCIRGFLL 238 +ET A Y+ + + +N TK WI + + V +A+ +D R F++ Sbjct: 178 KGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVV 237 Query: 239 E-------KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSL-------- 283 G+S I K G I V +P +N+L + + Sbjct: 238 PLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTK 297 Query: 284 ----GGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGV-------PLARNQLI 332 +G L R + S+ L A +YA R QFG + Sbjct: 298 PALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYH 357 Query: 333 QKKLADMLTEITLGLHACLQLGRLK--------------------------DQDKAAPEM 366 Q++L +L + + D + Sbjct: 358 QRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAAS 417 Query: 367 VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426 + K I + R GG+G S + + T+EG +++ L +GR Sbjct: 418 AGM-KAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGR 476 Query: 427 AIT 429 + Sbjct: 477 GLV 479 >3U33-A nrPDB Length = 541 Score = 224 bits (572), Expect = 5e-59, Method: Composition-based stats. Identities = 64/285 (22%), Positives = 109/285 (38%), Gaps = 18/285 (6%) Query: 157 SEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS 216 S+ LP K LL G+TE GSD S TRA + SY L G K + + Sbjct: 162 SDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAE-RLEDGSYRLVGHKWFFS-V 219 Query: 217 PMADLFVVWARCEDGCIRGFLLEKGMR-----GLSAPRIQGKFSLRASATGMIIMDGVEV 271 P +D +V A+ G + F + + + + R++ K R++A+ + Sbjct: 220 PQSDAHLVLAQTA-GGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA-- 276 Query: 272 PEENVLP-GASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQ 330 +L + R+ A G A +A R FG PL + Sbjct: 277 -IGWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQP 335 Query: 331 LIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPE------MVSLLKRNNCGKALDIARQ 384 L++ L+ M ++ +L R D+ A E K C + + + Sbjct: 336 LMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFVAE 395 Query: 385 ARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT 429 A ++LGG G +E + R + + +EG+ +I L + R + Sbjct: 396 AMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLN 440 >5EZ3-A nrPDB Length = 573 Score = 212 bits (540), Expect = 3e-55, Method: Composition-based stats. Identities = 85/438 (19%), Positives = 160/438 (36%), Gaps = 44/438 (10%) Query: 29 QTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILI-----RDTFRTYCQERLMPRI 83 QT T + L + + P L +L + +D R L P++ Sbjct: 40 QTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLAR-LANTEL-PKL 97 Query: 84 LLANRNEV---------FHREIISEMGELGVLGPTIK----GYGCAGVSSVA--YGLLAR 128 +R + ++ G+ + G + A Y Sbjct: 98 RTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQL 157 Query: 129 ELERVDSGYRSAMSVQSSLVMHPIYAYGSEE-QRQKY----LPQLAKGELLGCFGLTEPN 183 E + ++ S+ + + +Y S +KY P K + G+TE Sbjct: 158 EAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQ 217 Query: 184 SGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK--- 240 G+D + TRA + ++ L G K +++ +PM+D F+ A+ ++G + FLL + Sbjct: 218 GGTDVRANATRAE-PAIGGAWRLTGHKWFMS-APMSDAFLTLAQTKEG-LSCFLLPRLGE 274 Query: 241 --GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIA 298 G R++ K R++A+ + DG + + + + R A Sbjct: 275 KGESNGFFFQRLKDKLGNRSNASSEVEFDGAL--GQMIGSPGEGVKTIMDMVTLTRLDCA 332 Query: 299 WGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD 358 G L A ++ R FG PL L+Q+ LADM ++ ++L R D Sbjct: 333 VASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFD 392 Query: 359 QDKAAPEMVSLL-------KRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVN 411 + + K C A + +A + LGGNG ++ ++ R Sbjct: 393 MAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNA 452 Query: 412 TYEGTHDIHALILGRAIT 429 +EG+ ++ AL + R ++ Sbjct: 453 IWEGSGNVMALDVARVLS 470 >5GJ7-A nrPDB Length = 398 Score = 201 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 80/384 (20%), Positives = 138/384 (35%), Gaps = 31/384 (8%) Query: 44 SRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGEL 103 S +D L + + RD + + + +R F E I ++ Sbjct: 1 SNAMYDIYGEAALPADVRERLRITRDLAQAFHER-----APEHDRAGDFPFENIEDLKAS 55 Query: 104 GVLGPTIK-GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGS--EEQ 160 G + T+ YG G+S + L + D A+ +++H + G+ +E Sbjct: 56 GYVRWTVPVEYGGLGLSLEEMLMHQEVLAKGDGSTALAIGWHVGILLH-LRETGAFPDEL 114 Query: 161 RQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMAD 220 + + K L TEP +GS + Y + G KT+ T SP Sbjct: 115 FRMVCESVVKEGALINSCATEPATGSPSRGGKPETTAVKVPGGYRITGRKTFSTLSPALT 174 Query: 221 LFVVWARCEDGCIRG-FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL-- 277 +V A D + G FL+ K + +RA+ + I++ V VPEE V+ Sbjct: 175 WIMVTATVADEDVVGQFLVRK--EDVEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVI 232 Query: 278 --PGASSLGGPFGC-----LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQ 330 PG + P G + GIA L A +F L A Y + + P+A Sbjct: 233 QRPGVQAERRPDGSGWLLHIPACYLGIA---LAARDFALEYAATYRPNTLPH--PIAEVP 287 Query: 331 LIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPE-----MVSLLKRNNCGKALDIARQA 385 +++KL +M ++ L R D +K A + A Sbjct: 288 HVEQKLGEMELKLLAARTLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLA 347 Query: 386 RDMLGGNGISDEYHVIRHAMNLEA 409 ++GG +S + R+ ++ A Sbjct: 348 MRVVGGRSLSRALPLERYYRDVRA 371 >4XVX-A nrPDB Length = 389 Score = 200 bits (508), Expect = 1e-51, Method: Composition-based stats. Identities = 72/376 (19%), Positives = 143/376 (38%), Gaps = 17/376 (4%) Query: 62 TDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSV 121 +D R ER++ A E F R++I +G GV V + Sbjct: 8 SDLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKL 67 Query: 122 AYGLLARELER-VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180 LA L + +G +S+ S + + +G + + Q +G + C G + Sbjct: 68 --VELAFALGQLASAGIGVGVSLHDSAIA-ILRRFGKSDYLRDICDQAIRGAAVLCIGAS 124 Query: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIR-----G 235 E + GSD +ET S + + + G K +++ SP+AD +V AR D Sbjct: 125 EESGGSDLQIVET--EIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNV 182 Query: 236 FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGCLNNAR 294 ++ +S K T + +D VP + ++ + L L + R Sbjct: 183 AVVAVPAAQVSVQTPYRKVGAGPLDTAAVCID-TWVPADALVARAGTGLAAISWGLAHER 241 Query: 295 YGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLG 354 IA + + + + + R QFG L +Q ++ ++AD+ + L +A + Sbjct: 242 MSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIA 301 Query: 355 RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGIS-DEYHVIRHAMNLEAVNTY 413 +Q + + +K ++ + + GG G DE + + +++ Sbjct: 302 ---EQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVG 358 Query: 414 EGTHDIHALILGRAIT 429 GT ++ ++ +T Sbjct: 359 GGTDEVLWELVAAGMT 374 >4X28-A nrPDB Length = 400 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 87/406 (21%), Positives = 149/406 (36%), Gaps = 41/406 (10%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLANRN-------EVFHREIISEMGELGVLGP 108 + T + +R R+Y + P A + +RE I++MG G L Sbjct: 1 MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLAL 60 Query: 109 TIK-GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQ 167 YG G S++ + E + +++ S V I AYG++EQ++ +LP+ Sbjct: 61 GWPKEYGGQGRSAMDQLIFTDE-AAIAGAPVPFLTINS--VAPTIMAYGTDEQKRFFLPR 117 Query: 168 LAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWAR 227 +A G+L G +EP +G+D +++ T A + + Y +NG K W + AD + R Sbjct: 118 IAAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDD--YVVNGQKMWTSLIQYADYVWLAVR 175 Query: 228 CEDG--------CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG 279 I ++ G S + SAT V VP N + Sbjct: 176 TNPESSGAKKHRGISVLIVPTTAEGFSWTPVHTMAGPDTSAT---YYSDVRVPVANRVGE 232 Query: 280 AS-SLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRM-QFGVPLARNQLIQKKLA 337 + LN+ R +A CL R++A + G L ++ +Q LA Sbjct: 233 ENAGWKLVTNQLNHER--VALVSPAPIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLA 290 Query: 338 DMLTEITLGLHACLQLGR----LKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGN- 392 + + + +L KD +P S K A + R ++LG Sbjct: 291 RVHAKAEVLKLINWELASSQSGPKDAG-PSPADASAAKVFGTELATEAYRLLMEVLGTAA 349 Query: 393 -------GISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGI 431 G V R + GT+++ I+G G+ Sbjct: 350 TLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMVALGL 395 >4X28-D nrPDB Length = 373 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 72/384 (18%), Positives = 133/384 (34%), Gaps = 27/384 (7%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMP-RILLANR-NEVFHREIISEMGELGVLG-PTIKG 112 ++ T + T P ++ + F RE+ ++ + G+L + Sbjct: 1 MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPES 60 Query: 113 YGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGE 172 G G + + L + SV L + +GS E +Q + G+ Sbjct: 61 LGGDGFGVLEQVAVLVALGHQLAAVPYLESV--VLAAGALARFGSPELQQGWGVSAVSGD 118 Query: 173 LLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC 232 + L + G P H Y L GT+T + P+AD F+V A + G Sbjct: 119 RILTVAL-DGEMGEGPVQAAGTGH------GYRLTGTRTQVGYGPVADAFLVPAETDSGA 171 Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNN 292 FL+ G G++ + + + G + ++G +V + G + + G L+ Sbjct: 172 -AVFLVAAGDPGVAVTALA---TTGLGSVGHLELNGAKVDAARRVGG-TDVAVWLGTLST 226 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 LG E L +YA R QF P+ Q + ++LAD ++ Q Sbjct: 227 --LSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQ 284 Query: 353 LGRLKDQD--------KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHA 404 +D + A V+ +A + GG G+ ++ V R+ Sbjct: 285 AAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYF 344 Query: 405 MNLEAVNTYEGTHDIHALILGRAI 428 + + G +GR + Sbjct: 345 LAAKQTEFALGGATGQLRRIGREL 368 >1W07-A nrPDB Length = 659 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 67/358 (18%), Positives = 126/358 (35%), Gaps = 60/358 (16%) Query: 128 RELER--VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSG 185 E R + + + + + I G+EEQ++K+L K +++GC+ TE G Sbjct: 84 EEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHG 143 Query: 186 SDPSSMETRAHYNSSNKSYTLN-----GTKTWITN-SPMADLFVVWARC----EDGCIRG 235 S+ +ET A + + ++ +K W ++ VV+AR +D I G Sbjct: 144 SNVQGLETTATLDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHG 203 Query: 236 FLLE-------KGMRGLSAPRIQGKFS---LRASATGMIIMDGVEVPEENVL-------- 277 F+++ + ++ I K + G ++ D V +P + +L Sbjct: 204 FIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTR 263 Query: 278 -----PGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLI 332 P +G + R I A + A +Y+ R QFG A N I Sbjct: 264 EGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGI 320 Query: 333 QKKLADMLTEITLGLHACLQLGRLKDQDK-------------AAPEMVSLLKRNNCGKAL 379 + ++ D T+ + + AA + +L + + C L Sbjct: 321 ETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGL 380 Query: 380 DI---------ARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 + R + GG+G + TYEG + + L + R + Sbjct: 381 KSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 >2FON-A nrPDB Length = 683 Score = 188 bits (478), Expect = 4e-48, Method: Composition-based stats. Identities = 64/341 (18%), Positives = 122/341 (35%), Gaps = 58/341 (17%) Query: 143 VQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNK 202 + + + I G+++Q++K+LP K +++GC+ TE GS+ +ET A ++ Sbjct: 120 LHWGMFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTD 179 Query: 203 SYT-----LNGTKTWITN-SPMADLFVVWARC----EDGCIRGFLLE-------KGMRGL 245 + L +K W ++ VV+AR +D + GF+++ K + G+ Sbjct: 180 EFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGV 239 Query: 246 SAPRIQGKFS---LRASATGMIIMDGVEVPEENVLPGAS-------------SLGGPFGC 289 + I KF + G++ D V +P + +L S +G Sbjct: 240 TVGDIGMKFGNGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGT 299 Query: 290 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 349 + R I A + A +Y+ R QFG ++N + ++ D T+ Sbjct: 300 MVYVRQSIVADASLAMSRAVCIATRYSAVRRQFG---SQNGGQETQVIDYKTQQNRLFPL 356 Query: 350 CLQLGRLKDQDK----------------------AAPEMVSLLKRNNCGKALDIARQARD 387 + + A + LK D + R Sbjct: 357 LASAYAFRFVGEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEECRK 416 Query: 388 MLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428 + GG+G + TYEG + + L + R + Sbjct: 417 LCGGHGYLCSSGLPELFAVYVPACTYEGDNVVLQLQVARFL 457 >4ZYJ-A nrPDB Length = 425 Score = 185 bits (469), Expect = 4e-47, Method: Composition-based stats. Identities = 70/348 (20%), Positives = 128/348 (36%), Gaps = 32/348 (9%) Query: 84 LLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSV-AYGLLARELERVDSGYRSAM 141 +R + M + GVLG T+ + G GV S+ L + D+G A+ Sbjct: 65 RDNDREATLPVHLFDRMRKEGVLGATVPEDLGGLGVHSLHDVALALARIAGRDAGVALAL 124 Query: 142 SVQSS--LVMHPIYAYGSEEQR---QKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAH 196 +Q S L + + +G+ R + L Q+ GE + C + + T Sbjct: 125 HMQFSRGLTLDFEWRHGAPSTRPLAEDLLRQMGAGEAVICGAVKDVRG--------TTVL 176 Query: 197 YNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEKGMRGLSAPRIQG 252 +++ SY LNG KT ++ + +A +VV R E+ + ++ + GL+ Sbjct: 177 TRATDGSYRLNGRKTLVSMAGIATHYVVSTRLEEAGAPVRLAAPVVARTTPGLTVLDNWD 236 Query: 253 KFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWGV---LGASEFCL 309 +R+S + I+ DG V + VLP L + +G +E Sbjct: 237 GMGMRSSGSVDIVFDGCPVDRDRVLPRGEPGVRDDAALAGQTVSSIAMLGIYVGIAEAAR 296 Query: 310 HTARQYALDRMQFGVPLARNQLIQK---KLADMLTEITLGLHACLQLGRLKDQDKAAPEM 366 A R G P + + +L + T + L +L D AA Sbjct: 297 RIALTELRRR--GGAPAGVRTTVAEIDARLFALHTAVASALTTADRLADDLSGDLAARGR 354 Query: 367 VSL-----LKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 + K ++ + ++GG G S+ + + R ++ A Sbjct: 355 AMMTPFQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRA 402 >4Y9J-A nrPDB Length = 593 Score = 169 bits (427), Expect = 3e-42, Method: Composition-based stats. Identities = 62/330 (18%), Positives = 122/330 (36%), Gaps = 31/330 (9%) Query: 131 ERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG----LTEPNSGS 186 AM+ + + + YG + + + +L + + +TE GS Sbjct: 138 SAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGS 197 Query: 187 DPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG---------CIRGFL 237 D + +Y L+G K W +++ AD+ + AR D + FL Sbjct: 198 DVAGGCDTYAVQIDKDTYRLHGYK-WFSSAVDADVALTLARIVDSDGNALEGSRGLSLFL 256 Query: 238 LE-----KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNN 292 L+ + G+ R++ K + T +++DG E + + G LN Sbjct: 257 LKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGA--IAERIGDQGRGVAGISNMLNI 314 Query: 293 ARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQ 352 R A LG + AR Y+ R+ FG ++ L LA M + + + Sbjct: 315 TRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFE 374 Query: 353 LGRL---KDQDKAAPEMVSLL-------KRNNCGKALDIARQARDMLGGNGISDEYHVIR 402 RL + K++ +L K +A+ + + + GG G ++ + Sbjct: 375 AARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPT 434 Query: 403 HAMNLEAVNTYEGTHDIHALILGRAITGIQ 432 + + +EGT ++ +L + R +G + Sbjct: 435 LLRDAQVTPIWEGTTNVLSLDVLRVFSGKE 464 >3M9V-A nrPDB Length = 439 Score = 168 bits (426), Expect = 4e-42, Method: Composition-based stats. Identities = 63/361 (17%), Positives = 131/361 (36%), Gaps = 38/361 (10%) Query: 78 RLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSV-AYGLLARELERVDS 135 R+ +R+ F + + + G++G T+ G GV + + + R D+ Sbjct: 37 RIRSTAAEHDRDGTFPTDTFDALRKDGLMGATVPAELGGLGVDRLYDVAVALLAVARADA 96 Query: 136 GYRSAMSVQSS--LVMHPIYAYGSEEQR---QKYLPQLAKGELLGCFGLTEPNSGSDPSS 190 A+ +Q S L + + +G E R ++ L + G+ + C G+ D + Sbjct: 97 STALALHMQLSRGLTLGYEWRHGDERARTLAERILRGMVAGDAVVCSGIK------DHHT 150 Query: 191 METRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEKGMRGLS 246 T + + + L+G KT ++ +P+ FV+ AR + + ++ + G + Sbjct: 151 AVTTLRPDGAGG-WLLSGRKTLVSMAPVGTHFVINARTDGTDGPPRLASPVVTRDTPGFT 209 Query: 247 APRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNN---ARYGIAWGVLG 303 +RAS T I+ D +P ++VL L + + +G Sbjct: 210 VLDNWDGLGMRASGTVDIVFDDCPIPADHVLMRDPVGARNDAVLAGQTVSSVSVLGVYVG 269 Query: 304 ASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA---------CLQLG 354 ++ TA AL+R P +A++ + + L Sbjct: 270 VAQAAYDTAVA-ALER----RPEPPQAAALTLVAEIDSRLYALRATAGSALTAADALSAD 324 Query: 355 RLKDQDKAAPEMV---SLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVN 411 D D+ +M+ K A +I ++GG + + + R +++A Sbjct: 325 LSGDMDERGRQMMRHFQCAKLAVNRLAPEIVSDCLSLVGGASYTAGHPLARLLRDVQAGR 384 Query: 412 T 412 Sbjct: 385 F 385 >5K3J-A nrPDB Length = 674 Score = 164 bits (415), Expect = 7e-41, Method: Composition-based stats. Identities = 71/360 (19%), Positives = 131/360 (36%), Gaps = 50/360 (13%) Query: 129 ELERVDSGY-RSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSD 187 L R GY ++ +L + + + S+EQ++K+L + + E++GC+ TE GS+ Sbjct: 98 HLHREVIGYEGHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSN 157 Query: 188 PSSMETRAHYNSSNKSYTLNGT-----KTWIT-NSPMADLFVVWARC----EDGCIRGFL 237 ++ET A Y+ +++ + L+ K W + +V A + F+ Sbjct: 158 LRNLETTAVYDIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRNNYGPHFFM 217 Query: 238 LEK-------GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG----------- 279 ++ ++G++ I K + A+ G + ++ + VP N+L Sbjct: 218 VQLRDEKTHIPLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTNLLMRHCKVEADGTYV 277 Query: 280 -ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQF---GV----PLARNQL 331 + + R +A L A +Y+ R Q + Q Sbjct: 278 KPPHAKIGYSGMVKIRSQMAMEQGLFLAHALTIAARYSAVRRQGHLDDKQVEVKVLDYQT 337 Query: 332 IQKK----LADMLTEITLGL---HACLQLGRLKDQD-----KAAPEMVSLLKRNNCGKAL 379 Q + LA I G H QL + D + S LK + Sbjct: 338 QQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVAHETG 397 Query: 380 DIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAIT-GIQAFTASK 438 + QAR GG+G S ++ TY G + + L L R + ++ A K Sbjct: 398 EGIEQARMACGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLVKSVELIKAGK 457 >3MXL-A nrPDB Length = 395 Score = 158 bits (399), Expect = 5e-39, Method: Composition-based stats. Identities = 63/358 (17%), Positives = 123/358 (34%), Gaps = 38/358 (10%) Query: 78 RLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSV-AYGLLARELERVDS 135 R+ +R F E + +LG++G T+ G G++ + L D+ Sbjct: 26 RISAEAADRDRTGTFPVEAFEQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAEADA 85 Query: 136 GYRSAMSVQSS--LVMHPIYAYGSE---EQRQKYLPQLAKGELLGCFGLTEPNSGSDPSS 190 A VQ S L + + +G+ ++ L +A+GE C L D Sbjct: 86 STALAWHVQLSRGLTLTYEWQHGTPPVRAMAERLLRAMAEGEAAVCGALK------DAPG 139 Query: 191 METRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWA--RCEDGCI--RGFLLEKGMRGLS 246 + T H + + + L+G K ++ +P+A F V A R +DG + ++ + GL+ Sbjct: 140 VVTELHSDGAGG-WLLSGRKVLVSMAPIATHFFVHAQRRDDDGSVFLAVPVVHRDAPGLT 198 Query: 247 APRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNN---ARYGIAWGVLG 303 +RAS T ++ D V + +L L + + G Sbjct: 199 VLDNWDGLGMRASGTLEVVFDRCPVRADELLERGPVGARRDAVLAGQTVSSITMLGIYAG 258 Query: 304 ASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGL------------HACL 351 ++ A + R G P A + +A + T + + Sbjct: 259 IAQAARDIAVGFCAGR--GGEPRA---GARALVAGLDTRLYALRTTVGAALTNADAASVD 313 Query: 352 QLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 G ++ + K A + ++GG + + + R ++ A Sbjct: 314 LSGDPDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVRA 371 >1IS2-A nrPDB Length = 661 Score = 156 bits (395), Expect = 2e-38, Method: Composition-based stats. Identities = 61/344 (17%), Positives = 113/344 (32%), Gaps = 48/344 (13%) Query: 136 GYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRA 195 G+ + + + + + + EQ++++ E+ G + TE G+ +ET A Sbjct: 95 GHPEPLDLHLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTA 154 Query: 196 HYNSSNKSYTLNGT-----KTWITN-SPMADLFVVWARC----EDGCIRGFLLE------ 239 Y+ + + LN K W ++ +V A+ E + F++ Sbjct: 155 TYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGT 214 Query: 240 -KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL------------PGASSLGGP 286 K + G++ I KF G + MD +P EN+L S Sbjct: 215 HKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLT 274 Query: 287 FGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQF----GVP---LARNQLIQKK---- 335 +G + R + + A +Y+ R Q P + Q Q K Sbjct: 275 YGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPL 334 Query: 336 LADMLTEITLGLHACLQLGRLKDQ-DKAAPEM-------VSLLKRNNCGKALDIARQARD 387 LA +G + R+ + + + LK A + R Sbjct: 335 LATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRM 394 Query: 388 MLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGI 431 GG+G S + + T+EG + + L R + I Sbjct: 395 ACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKI 438 >5K3G-A nrPDB Length = 684 Score = 155 bits (392), Expect = 3e-38, Method: Composition-based stats. Identities = 66/349 (18%), Positives = 126/349 (36%), Gaps = 50/349 (14%) Query: 138 RSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHY 197 + M++ + + + A S+EQ+ K+L + + E++G + TE G++ ++ET A Y Sbjct: 110 GNPMALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATY 169 Query: 198 NSSNKSYTLNGT-----KTWITN-SPMADLFVVWA----RCEDGCIRGFLLE-------K 240 + + + L+ K W N ++ VV A + ++ F++ K Sbjct: 170 DIGTQEFVLHTPKITALKWWPGNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHK 229 Query: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSL------------GGPFG 288 + G++ I K + G + + +P N+L + + + Sbjct: 230 PLPGITIGDIGPKMAYNIVDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYS 289 Query: 289 CLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGV--------PLARNQLIQKKL---- 336 + + R + G + L+ A +Y+ R Q G + Q Q +L Sbjct: 290 AMVHVRSYMLTGQAIMLSYALNIATRYSAVRRQ-GQIDKNEPEVKVLEYQTQQHRLFPFI 348 Query: 337 AD-MLTEITLGLHACLQLGRLKDQDKAAPE-------MVSLLKRNNCGKALDIARQARDM 388 A + L LK+ + S LK + + QAR Sbjct: 349 ARAYAFQFAGAETVKLYERVLKEMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMA 408 Query: 389 LGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTAS 437 GG+G S ++ TYEG + + L L R + A S Sbjct: 409 CGGHGYSMASYISEIYGVAIGGCTYEGENMVMLLQLARYLVKSAALVKS 457 >3MKH-A nrPDB Length = 438 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 61/407 (14%), Positives = 119/407 (29%), Gaps = 48/407 (11%) Query: 54 LVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREI--------ISEMGELGV 105 + ++ L+ + R+ + LMP + + + G+ Sbjct: 1 MAIDFHLSASQKGTYQAARSLARNLLMP-ARQTYLQHPPNSPLRFQSTQPTYAAAVSAGI 59 Query: 106 L-GPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKY 164 L G +G G + + +L E V+ + + L + PI Q ++ Sbjct: 60 LKGQISPAHGGTGGTLIESAILVEECYSVEPSAALTIFA-TGLGLTPINLAAGP-QHAEF 117 Query: 165 LPQLAKGE--LLGCFGLTEPNSGSDPS-----SMETRAHYNSSNKSYTLNGTKTWITNSP 217 L GE L +EP ++ +T A + +NG K W TN Sbjct: 118 LAPFLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARL--EGDEWVINGEKMWATNCA 175 Query: 218 M-----ADLFVVWARCE----------DGCIRGFLLEK------GMRGLSAPRIQGKFSL 256 DL V R + + L+ + G R Sbjct: 176 GWDFKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGH 235 Query: 257 RASATGMIIMDGVEVPEENVL-PGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQY 315 + + + V VP +NVL P FG + + + +G A ++ Sbjct: 236 TSVSGPHVRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKF 295 Query: 316 ALDRMQFGV-PLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD----KAAPEMVSLL 370 A + + G PL Q L+ + + + + A E+ Sbjct: 296 AKEDNRGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAA 355 Query: 371 KRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTH 417 K A+ + +G + + + ++G + Sbjct: 356 KVFCSEAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGN 402 >2C12-A nrPDB Length = 439 Score = 138 bits (349), Expect = 3e-33, Method: Composition-based stats. Identities = 66/408 (16%), Positives = 128/408 (31%), Gaps = 50/408 (12%) Query: 56 LEEQLTTDEILIRDTFRTYCQERLMPRILLA----NRNEVFH--REIISEMGELGVLGPT 109 ++ +L+ ++ R + + L ++ F R E G++ Sbjct: 2 VDFKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKAQ 61 Query: 110 IK-GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQL 168 + G S V ++ EL V+ + V ++L + P+ S ++K+L Sbjct: 62 VPIPLGGTMESLVHESIILEELFAVEPATSITI-VATALGLMPVILCDSPSLQEKFLKPF 120 Query: 169 AKGE--LLGCFGLTEPNSGSD-----PSSMETRAHYNSSNKSYTLNGTKTWITNSPM--- 218 GE L +EPN ++ ++T A + ++G K W +NS Sbjct: 121 ISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTA--RKVGNEWVISGEKLWPSNSGGWDY 178 Query: 219 --ADLFVVWARCED-------------GCIRGFLLEKGMRGLS-------APRIQGKFSL 256 ADL V R D I L+ + + + + Sbjct: 179 KGADLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEPELAGHI 238 Query: 257 RASATGMIIMDGVEVPEENVL--PGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQ 314 S VP EN+L PG + G + + +G + A Sbjct: 239 TTSGP-HTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVGAMAIGTARAAFEEALV 297 Query: 315 YALDRMQFG-VPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD----QDKAAPEMVSL 369 +A + G + +Q + KL D + + + + K EM Sbjct: 298 FAKSDTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQ 357 Query: 370 LKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTH 417 K A++ A +G + + R + ++G + Sbjct: 358 TKIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGN 405 >5XDD-A nrPDB Length = 414 Score = 128 bits (322), Expect = 4e-30, Method: Composition-based stats. Identities = 58/363 (15%), Positives = 112/363 (30%), Gaps = 34/363 (9%) Query: 82 RILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSA 140 + R + + G+L I K G G S E+ D+ Sbjct: 31 TVRERERAGGTPKAERDAIRRSGLLTLLISKERGGLGESWPTVYEAIAEIASADASLGHL 90 Query: 141 MSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSS 200 S + + + S EQ+ ++ PQ + +E N+ A Sbjct: 91 FGYHFSNFAY-VDLFASPEQKARWYPQAVRERWFLGNASSENNA--HVLDWRVTATPLPD 147 Query: 201 NKSYTLNGTKTWITNSPMADLFVVWARC-----EDGCIRGFLLEKGMRGLSAPRIQGKFS 255 SY +NGTK + + S AD +V+A DG I L+ G+ Sbjct: 148 -GSYEINGTKAFCSGSADADRLLVFAVTSRDPNGDGRIVAALIPSDRAGVQVNGDWDSLG 206 Query: 256 LRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLN-------NARYGIAWGVLGASEFC 308 +R + +G + GV V + +L + F + + LG + Sbjct: 207 MRQTDSGSVTFSGVVVYPDELLGTPGQVTDAFASGSKPSLWTPITQLIFTHLYLGIARGA 266 Query: 309 LHTARQYALDR-MQFG----VPLARNQLI----QKKLADMLTEITLGLHACLQLGRLKDQ 359 L A Y+ F + + + A + L++ L ++ Sbjct: 267 LEEAAHYSRSHSRPFTLAGVEKATEDPYVLAIYGEFAAQLQVAEAGAREVALRVQELWER 326 Query: 360 DKAAPE-------MVSLLKRNNCGKALDIARQARDMLGGN-GISDEYHVIRHAMNLEAVN 411 + PE V+ K +++ + + +G S ++ R + Sbjct: 327 NHVTPEQRGQLMVQVASAKIVATRLVIELTSRLYEAMGARAAASRQFGFDRFWRDARTHT 386 Query: 412 TYE 414 ++ Sbjct: 387 LHD 389 >4JEK-A nrPDB Length = 453 Score = 122 bits (307), Expect = 3e-28, Method: Composition-based stats. Identities = 72/417 (17%), Positives = 133/417 (31%), Gaps = 58/417 (13%) Query: 39 QLAKSSRPEFDWQDPLVLEEQLTTDEILIR----------DTFRTYCQERLMPRILLANR 88 Q+ + S L+ ++ +R R ++ + +R Sbjct: 29 QMGRGSEF-----------MTLSPEKQHVRPRDAADNDPVAVARGLAEKWRA-TAVERDR 76 Query: 89 NEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSL 147 ++ G+L + YG G + RE+ D + Sbjct: 77 AGGSATAEREDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLT- 135 Query: 148 VMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLN 207 I GS+EQ + Q+A+ +E + S + A + Y LN Sbjct: 136 NAPMIELIGSQEQEEHLYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPT-EDGGYVLN 192 Query: 208 GTKTWITNSPMADLFVVWARCED-----GCIRGFLLEKGMRGLSAPRIQGKFSLRASATG 262 GTK + + + +DL V+ +D G I + G++ +R + +G Sbjct: 193 GTKHFCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSG 252 Query: 263 MIIMDGVEVPEENVLPGASSLGGPF-----GCL--NNARYGIAWGVLGASEFCLHTARQY 315 V+V + VL ++ F G L A+ A LG + L AR+Y Sbjct: 253 STDFHNVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREY 312 Query: 316 ALDRMQFGVPLARNQLI----------QKKLADMLTEITLGLHACLQLGRLKDQDKAAPE 365 + + P Q + +A + A L + D+ A Sbjct: 313 TRTQARPWTPAGIQQATEDPYTIRSYGEFTIA-LQGADAAAREAAHLLQTVWDKGDALTP 371 Query: 366 M--------VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 414 VS +K AL+I+ +++G G Y R N+ + ++ Sbjct: 372 EDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSLHD 428 >2JBS-A nrPDB Length = 422 Score = 88.5 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 59/387 (15%), Positives = 122/387 (31%), Gaps = 52/387 (13%) Query: 78 RLMPRILLANRNEVFHREIISEMGELGVLGP-TIKGYGCAGVSSVAYGLLARELERVDSG 136 ++ A + E I + E+G+ K YG +S + L +G Sbjct: 50 QIAKNAESAEQLRRVPDENIKLLKEIGLHRAFQPKVYGGLEMSLPDFANCIVTLAGACAG 109 Query: 137 YRSAMSVQSSLVMHP--IYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETR 194 A S+ L H I + + Q + +L +P++ + SS+ Sbjct: 110 TAWAFSL---LCTHSHQIAMFSKQLQDEIWLK--------------DPDA-TASSSIAPF 151 Query: 195 AHYNSSNKSYTLNGTKTWITNSPMADLFVV-WAR--CEDGCIRGF-LLEKGMRGLSAPRI 250 LNG W + A+ +V + R + I F ++ + Sbjct: 152 GKVEEVEGGIILNGDYGWSSGCDHAEYAIVGFNRFDADGNKIYSFGVIPRSD--YEIVDN 209 Query: 251 QGKFSLRASATGMIIMDGVEVPEENVLPGA---SSLGGPFGCLNNARY-----------G 296 ++++S + M+ + V +PE + FG +++ G Sbjct: 210 WYAQAIKSSGSKMLKLVNVFIPEYRISKAKDMMEGKSAGFGLYPDSKIFYTPYRPYFASG 269 Query: 297 IAWGVLGASEFCLHT--ARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA---CL 351 + LG +E + +Q R G + ++A+ ++ Sbjct: 270 FSAVSLGIAERMIEAFKEKQRNRVRAYTGANVGLATPALMRIAESTHQVAAARALLEKTW 329 Query: 352 QLGRLKDQDKAAPEMVSLLKR-----NNCGKALDIARQARDMLGGNGISDEYHVIRHAMN 406 + R+ + P +L ++ + G D + R + Sbjct: 330 EDHRIHGLNHQYPNKETLAFWRTNQAYAVKMCIEAVDRLMAAAGATSFMDNSELQRLFRD 389 Query: 407 LEAVNTYEGTH-DIHALILGRAITGIQ 432 + T D+ A ILGR + G++ Sbjct: 390 AHMTGAHAYTDYDVCAQILGRELMGME 416 >2RFQ-A nrPDB Length = 394 Score = 82.0 bits (201), Expect = 5e-16, Method: Composition-based stats. Identities = 48/363 (13%), Positives = 104/363 (28%), Gaps = 53/363 (14%) Query: 82 RILLANRNEVFHREIISEMGELGVLGP-TIKGYGCAGVSSVAYGLLARELERVDSGYR-- 138 R + + + E G + +G V + R++ Sbjct: 26 RAQETEDLRRIPDDSMKALQETGFFRLLQPEQWGGYQADPVLFYSAVRKIASACGSTGWV 85 Query: 139 -SAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHY 197 S + V + + + + Q + T+ S + M Sbjct: 86 SSIIGVHN----WHLALFSQQAQEDVWGND------------TDVRISSSYAPM---GAG 126 Query: 198 NSSNKSYTLNGTKTWITNSPMADLFVVWA-RCEDG---CIRGFLLEKGMRGLSAPRIQGK 253 + YT+NG W + A V+ +DG FL+ + + Sbjct: 127 QVVDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVDFVSFLIPR--EDYRIDDVWNV 184 Query: 254 FSLRASATGMIIMDGVEVPEENVL----------PGASSLGGPFGCLNNARYG---IAWG 300 LR + + ++++ V VP VL PG P + I+ Sbjct: 185 VGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVYKMPWGTIHPTTISAP 244 Query: 301 VLGASEFCLHTARQY--ALDRMQF-GVPLARNQLIQKKLADMLTEITLG-LHACLQLGRL 356 ++G + ++ R F G + + ++A+ ++I + Sbjct: 245 IVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSDIDAAWRQLSGNVADE 304 Query: 357 KD---QDKAAPEMVSLLKR----NNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 409 + P + L R G+A+ + + G +++ + R + A Sbjct: 305 YALLVAGEEVPFELRLRARRDQVRATGRAISSIDKLFESSGATALANGTPLQRFWRDAHA 364 Query: 410 VNT 412 Sbjct: 365 GRV 367 >3AFF-A nrPDB Length = 394 Score = 73.9 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 44/367 (11%), Positives = 101/367 (27%), Gaps = 53/367 (14%) Query: 78 RLMPRILLANRNEVFHREIISEMGELGVLGP-TIKGYGCAGVSSVAYGLLARELERVDSG 136 + R E + + ++G + +G + R L V Sbjct: 22 EIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGS 81 Query: 137 YR---SAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMET 193 S + V + + + Q + + + + + G+ Sbjct: 82 TGWVSSIVGVHN----WHLALFDQRAQEEVWGEDPST-RISSSYA----PMGAGVV---- 128 Query: 194 RAHYNSSNKSYTLNGTKTWITNSPMADLFVVWA-RCEDG---CIRGFLLEKGMRGLSAPR 249 + Y +NG+ W + A V +DG FL+ + Sbjct: 129 ------VDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSE--YEIKD 180 Query: 250 IQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNAR-------------YG 296 + LR + + +++ V VP L + G L Sbjct: 181 VWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTT 240 Query: 297 IAWGVLGASEFCLHTARQY--ALDRMQF-GVPLARNQLIQKKLADMLTEITLG-LHACLQ 352 I+ ++G + ++ R F G + + ++A+ ++I Sbjct: 241 ISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAWRQLIGN 300 Query: 353 LGRLKDQDKAAPEM-------VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAM 405 + A E+ + G+++ + + G +S+E + R Sbjct: 301 VSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWR 360 Query: 406 NLEAVNT 412 + A Sbjct: 361 DAHAGRV 367 >5LVW-A nrPDB Length = 413 Score = 71.6 bits (174), Expect = 7e-13, Method: Composition-based stats. Identities = 48/385 (12%), Positives = 99/385 (25%), Gaps = 65/385 (16%) Query: 61 TTDEI-LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGV-LGPTIKGYGCAGV 118 T + + + + + R + + + + + T K YG Sbjct: 24 TAELRAELVERVHKFG-PVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLET 82 Query: 119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 178 +A+ L ++ + GS K+ P+ A E+ G Sbjct: 83 DVRTMSEVAKVLSHYCPSTSWVVNNVN----------GSNLLASKF-PRAALDEVFGDA- 130 Query: 179 LTEPNSG-SDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCED------G 231 P + + + A Y L G+ + T D ++ AR D G Sbjct: 131 ---PGAKLASVFAAAGTAVRTP--GGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVG 185 Query: 232 CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC-- 289 + + + L+ +RA+ + +++ VPE V+ G Sbjct: 186 GLSMLVPARD---LTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDL 242 Query: 290 ----------LNNARYGIAWGVLGASEFCLHTARQYALDR-------------MQF---- 322 + A VLGA + + A R F Sbjct: 243 GLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSL 302 Query: 323 GVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIA 382 G + +A T + + + + V Sbjct: 303 GRTALSIDAAEMHVARAATALDDAAYDA--VALPDSELLRIRGDVGQA----VSLVTTAL 356 Query: 383 RQARDMLGGNGISDEYHVIRHAMNL 407 + G ++ + R+ + Sbjct: 357 DELLWAHGAASFAESNPLQRYWRDA 381 >2OR0-A nrPDB Length = 414 Score = 56.5 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 38/244 (15%), Positives = 70/244 (28%), Gaps = 34/244 (13%) Query: 195 AHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG--------CIRGFLLEKGMRGLS 246 + Y L G ++ + + + A DG + L + Sbjct: 137 GVATPVDGGYVLKGRWSFSSGTDHCQWAFLGAMVGDGEGGIATPSSLHVILPRTDYQ--I 194 Query: 247 APRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNAR------------ 294 LR + + +I+DG VP L A + R Sbjct: 195 VEDTWDVIGLRGTGSKDLIVDGAFVPGYRTLNAAKVM-DGRAQKEAGRPEPLFNMPYSCM 253 Query: 295 --YGIAWGVLGASEFCLHTARQYALDRMQF-GVPLARNQLIQKKLADMLTEITLGL-HAC 350 GI V+G +E L DR+ G + + + + + EI Sbjct: 254 FPLGITAAVIGITEGALACHIAVQKDRVAITGQKIKEDPYVLSAIGESAAEINASRVSLI 313 Query: 351 LQLGRLKDQ----DKAAPEMVSLLKRNNCGKALDIARQARDML---GGNGISDEYHVIRH 403 R D+ + E ++ +R A R A ++ GG + + + R Sbjct: 314 ETADRFYDKVDAGKEITFEERAIGRRTQIAAAWRAVRAADEIFARAGGGALHYKTPMQRF 373 Query: 404 AMNL 407 + Sbjct: 374 WRDA 377 >1U8V-A nrPDB Length = 490 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 43/298 (14%), Positives = 86/298 (28%), Gaps = 61/298 (20%) Query: 140 AMSVQSSLVMHPIYAYGSEEQRQ--KYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHY 197 A + S YG+ + +YL + + +L+ +T+P + A Sbjct: 108 AFNAVFSTTYEIDQKYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGD---RGLAPSAQK 164 Query: 198 NSS---------NKSYTLNGTKTWITNSPMADLFVVW---ARC--EDGCIRGFLLEKGMR 243 + + G K T S + ++ A + F Sbjct: 165 DPDLFLRIVEKREDGIVVRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVSFACPSDAD 224 Query: 244 GLSAP---------RIQGK----FSLR--ASATGMIIMDGVEVPEENV-LPGASSLGGPF 287 GL +++ + +++ D V +P + + L G Sbjct: 225 GLFMIYGRQSCDTRKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMM 284 Query: 288 ---------GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLAD 338 + G+ V+GA+ A Y + ++ KL + Sbjct: 285 VERFAGYHRQSYGGCKVGVGDVVIGAA----ALAADYNGAQKA--------SHVKDKLIE 332 Query: 339 ML---TEITLGLHACLQLGRLKDQD--KAAPEMVSLLKRNNCGKALDIARQARDMLGG 391 M + AC G + + ++ K+N +I R A D+ GG Sbjct: 333 MTHLNETLYCCGIACSAEGYPTAAGNYQIDLLLANVCKQNITRFPYEIVRLAEDIAGG 390 >2YYI-A nrPDB Length = 481 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 29/182 (15%), Positives = 53/182 (29%), Gaps = 31/182 (17%) Query: 195 AHYNSSNKSYTLNGTKTWITNSPMADLFVVWARC-----EDGCIRGFLLEKGMRGLSAP- 248 + K + G + T P+AD +++ + F L GL Sbjct: 166 GVVKQTEKGIVVRGARMTATF-PLADEVLIFPSTLLQAGSEKYALAFALPTSTPGLHFVC 224 Query: 249 RIQGKFSLRASAT----------GMIIMDGVEVPEENV--LPGASSLGGPF---GCLNNA 293 R ++I D V VP E V L + G LN+ Sbjct: 225 REALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHM 284 Query: 294 RYGIAWGVLGASEFCLHTARQYALDRMQFGVPLAR--NQLIQKKLADMLTEITLGLHACL 351 + + +E L A A + +Q+K+A+++ + Sbjct: 285 AHQVVALKTAKTEAFLGVAALMAEG-------IGADVYGHVQEKIAEIIVYLEAMRAFWT 337 Query: 352 QL 353 + Sbjct: 338 RA 339 >4Q0M-A nrPDB Length = 327 Score = 31.9 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 2/40 (5%) Query: 95 EIISEMGELGVLGPTIKGYGCAGVSSVAYGLL--ARELER 132 +I ELG G I+GYG G+ LL EL + Sbjct: 215 DIFRAAVELGYRGIVIEGYGAGGIPYRGSDLLQTIEELSK 254 >1AKL-A nrPDB Length = 470 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 47/123 (38%), Gaps = 15/123 (12%) Query: 104 GVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQK 163 G LG + +G AG + YG +A R +S Q + + + A+ + + Sbjct: 360 GGLGAD-QLWGGAGADTFVYGDIAESSAAAPDTLRDFVSGQDKIDLSGLDAFVNGGLVLQ 418 Query: 164 YLPQLA--KGELLGCF-GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMAD 220 Y+ A G+ + + + +GS AH + + +N I + AD Sbjct: 419 YVDAFAGKAGQAILSYDAAS--KAGSLAIDFSGDAHAD-----FAIN----LIGQATQAD 467 Query: 221 LFV 223 + V Sbjct: 468 IVV 470 >4QNW-A nrPDB Length = 392 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 23/67 (34%), Gaps = 9/67 (13%) Query: 336 LADMLTEITLGLHAC-----LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLG 390 LADM I+ L +D+ + + RN A++ ++ G Sbjct: 119 LADMKDLISSSAVPVEEKGPLPRALTEDEIQQCIADFAQAARN----AINAGFDGVEIHG 174 Query: 391 GNGISDE 397 NG + Sbjct: 175 ANGYLID 181 >1WYZ-A nrPDB Length = 242 Score = 30.3 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 8/56 (14%) Query: 145 SSLVMHPIYAYGSEEQRQKYLPQLAKGELL------GCFGLTEPNSGSDPSSMETR 194 SL +P+ + S E YL LA G + GC + +P + D ++ R Sbjct: 57 DSLTFYPLNKHTSPEDISGYLKPLAGGASMGVISEAGCPAVADPGA--DVVAIAQR 110 >2Q3R-A nrPDB Length = 372 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 5/26 (19%), Positives = 10/26 (38%) Query: 372 RNNCGKALDIARQARDMLGGNGISDE 397 R A++ ++ G NG + Sbjct: 166 RLAARNAMEAGFDGVEIHGANGYLID 191 >4C2U-A nrPDB Length = 665 Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 39/114 (34%), Gaps = 12/114 (10%) Query: 215 NSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGM-IIMDGVEVP- 272 +AD +D + + + + + + +L + V + Sbjct: 532 GGSIADFL------DDAALLSSVDDMRTKAENKGAPEDAVTLMTLHNAKGLEFPVVFIVG 585 Query: 273 -EENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVP 325 E+ +LP ++ + R G+ A E L TA A +RMQFG Sbjct: 586 VEQGLLPSKGAIAEGPSGIEEERRLFYVGITRAMERLLMTA---AQNRMQFGKT 636 >4C2T-A nrPDB Length = 745 Score = 28.8 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 39/114 (34%), Gaps = 12/114 (10%) Query: 215 NSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGM-IIMDGVEVP- 272 +AD +D + + + + + + +L + V + Sbjct: 532 GGSIADFL------DDAALLSSVDDMRTKAENKGAPEDAVTLMTLHNAKGLEFPVVFIVG 585 Query: 273 -EENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVP 325 E+ +LP ++ + R G+ A E L TA A +RMQFG Sbjct: 586 VEQGLLPSKGAIAEGPSGIEEERRLFYVGITRAMERLLMTA---AQNRMQFGKT 636 >2VFA-A nrPDB Length = 229 Score = 28.8 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 52 DPLVL--EEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMG 101 DP+ + ++ D +I ++ Y + L+P ++ NR E R+++ EMG Sbjct: 15 DPVFVKDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLARDVMKEMG 66 >1GPU-A nrPDB Length = 680 Score = 28.8 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 17/45 (37%) Query: 106 LGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMH 150 G K YG ++ V+Y A L + ++ S+ + Sbjct: 431 FGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVG 475 >4EWC-A nrPDB Length = 607 Score = 28.0 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 33/114 (28%), Gaps = 20/114 (17%) Query: 62 TDEILIRDTFRTYCQERLM---------PRILLANRNEVFHREIISEMGELGVLGPTIKG 112 ++ + R + +E M R+ F + + G + Sbjct: 65 DQDVYVDKKIRKFLEEEKMKDMSTRVSGAVAAAIERSVEFDNFSKEAAANIEMAGVDDEE 124 Query: 113 YGCAGV----------SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYG 156 G +G+ S++AY L + V + S S I+ G Sbjct: 125 AGGSGLVDNKRKNKGVSNMAYNLSLF-IGMVFPALTTFFSAILSEGEMSIWQNG 177 >5OQL-E nrPDB Length = 414 Score = 27.6 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 67 IRDTFRTYCQERLMPRILLANRNEVFHREIISEM 100 + D R + ER P + E+F ++ I + Sbjct: 4 VADKAR-FYLERAAPELREWEEKEIFTKDEIRNL 36 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.141 0.375 Lambda K H 0.267 0.0435 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,752,149 Number of Sequences: 36641 Number of extensions: 672813 Number of successful extensions: 2429 Number of sequences better than 10.0: 91 Number of HSP's better than 10.0 without gapping: 130 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 1807 Number of HSP's gapped (non-prelim): 168 length of query: 438 length of database: 10,336,785 effective HSP length: 100 effective length of query: 338 effective length of database: 6,672,685 effective search space: 2255367530 effective search space used: 2255367530 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)