BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q92506 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4CQL-A nrPDB 529 e-151 4JRO-A nrPDB 200 4e-52 3FTP-A nrPDB 192 1e-49 3OSU-A nrPDB 191 2e-49 2UVD-A nrPDB 188 2e-48 2HQ1-A nrPDB 184 3e-47 4NBV-A nrPDB 183 7e-47 2PNF-A nrPDB 180 6e-46 4BO1-A nrPDB 176 9e-45 4NBT-A nrPDB 175 1e-44 4KMS-A nrPDB 175 2e-44 4DMM-A nrPDB 174 3e-44 2PH3-A nrPDB 174 3e-44 3RSH-A nrPDB 172 1e-43 2C07-A nrPDB 172 2e-43 4M8S-A nrPDB 171 2e-43 3LYL-A nrPDB 171 3e-43 2CDH-G nrPDB 170 4e-43 1Q7C-A nrPDB 169 8e-43 3WOH-A nrPDB 167 4e-42 3F9I-A nrPDB 163 8e-41 4K6F-A nrPDB 161 3e-40 5CDY-A nrPDB 160 4e-40 4RZH-A nrPDB 160 4e-40 5VT6-A nrPDB 155 1e-38 2NM0-A nrPDB 154 3e-38 3VZS-A nrPDB 150 6e-37 3EMK-A nrPDB 148 3e-36 1UZM-A nrPDB 148 3e-36 3GRP-A nrPDB 147 4e-36 3EZL-A nrPDB 145 1e-35 4RZI-B nrPDB 144 3e-35 5OVL-A nrPDB 141 3e-34 5OVJ-A nrPDB 141 4e-34 3RWB-A nrPDB 138 3e-33 4IIV-A nrPDB 138 3e-33 1GEG-A nrPDB 138 3e-33 4IIN-A nrPDB 136 7e-33 3OEC-A nrPDB 134 4e-32 4Z9Y-A nrPDB 131 3e-31 4HP8-A nrPDB 130 4e-31 1GEE-A nrPDB 130 6e-31 6NRP-A nrPDB 130 8e-31 4CQM-B nrPDB 129 9e-31 5ITV-A nrPDB 127 5e-30 5T5Q-A nrPDB 127 6e-30 3AUT-A nrPDB 125 2e-29 6CI9-A nrPDB 125 2e-29 3WTC-A nrPDB 124 4e-29 2CFC-A nrPDB 123 7e-29 3WYE-A nrPDB 122 2e-28 2O23-A nrPDB 118 2e-27 1K2W-A nrPDB 118 3e-27 5B1Y-A nrPDB 116 9e-27 5O3Z-A nrPDB 116 1e-26 3U5T-A nrPDB 115 1e-26 1E3W-A nrPDB 115 2e-26 4IS3-A nrPDB 114 5e-26 4DBZ-A nrPDB 114 5e-26 1NFF-A nrPDB 112 1e-25 2EW8-A nrPDB 111 3e-25 1X1T-A nrPDB 111 4e-25 3A28-C nrPDB 109 1e-24 4E6P-A nrPDB 108 2e-24 4MOW-A nrPDB 108 3e-24 3V8B-A nrPDB 107 7e-24 5U9P-A nrPDB 106 1e-23 3PPI-A nrPDB 105 3e-23 3UF0-A nrPDB 104 3e-23 3T7C-A nrPDB 102 1e-22 3W8F-A nrPDB 102 1e-22 2Q2Q-A nrPDB 102 2e-22 5OJG-A nrPDB 101 3e-22 2ZAT-A nrPDB 101 3e-22 4DA9-A nrPDB 101 4e-22 3O4R-A nrPDB 101 4e-22 1AE1-A nrPDB 101 4e-22 5EJ2-A nrPDB 100 8e-22 3UVE-A nrPDB 100 8e-22 3V2H-A nrPDB 100 8e-22 2HSD-A nrPDB 100 9e-22 3V2G-A nrPDB 99 1e-21 4TRR-A nrPDB 99 2e-21 3OML-A nrPDB 98 3e-21 3D3W-A nrPDB 98 4e-21 2AG5-A nrPDB 97 7e-21 1CYD-A nrPDB 96 1e-20 4AVY-A nrPDB 96 2e-20 4EGF-A nrPDB 95 3e-20 5YSS-A nrPDB 95 4e-20 3GDF-A nrPDB 94 5e-20 1HXH-A nrPDB 93 1e-19 4CR6-A nrPDB 93 1e-19 3R3S-A nrPDB 92 3e-19 3UN1-A nrPDB 90 9e-19 2AE2-A nrPDB 89 2e-18 2GDZ-A nrPDB 86 1e-17 1AHH-A nrPDB 86 1e-17 1YXM-A nrPDB 86 2e-17 5IZ4-A nrPDB 85 3e-17 2FWM-X nrPDB 84 4e-17 2BGM-A nrPDB 84 7e-17 5JS6-A nrPDB 83 1e-16 1DOH-A nrPDB 83 1e-16 2B4Q-A nrPDB 83 2e-16 1O5I-A nrPDB 82 2e-16 1H5Q-A nrPDB 80 6e-16 3OIC-A nrPDB 79 1e-15 3ZV3-A nrPDB 79 2e-15 5JY1-A nrPDB 77 7e-15 2X9N-A nrPDB 77 7e-15 4FC7-A nrPDB 72 3e-13 1W73-A nrPDB 72 3e-13 4GKB-A nrPDB 69 2e-12 3U4C-A nrPDB 69 2e-12 1BDB-A nrPDB 65 3e-11 5ILO-A nrPDB 64 5e-11 1P33-A nrPDB 64 6e-11 2BFA-A nrPDB 63 1e-10 2QHX-A nrPDB 63 1e-10 4HBG-A nrPDB 62 3e-10 4DRY-A nrPDB 62 3e-10 4RGB-A nrPDB 55 4e-08 1FJH-A nrPDB 54 5e-08 2NWQ-A nrPDB 54 6e-08 3RKU-A nrPDB 51 5e-07 2DKN-A nrPDB 50 7e-07 3PXX-A nrPDB 49 2e-06 3OIG-A nrPDB 49 3e-06 6CGE-A nrPDB 46 1e-05 1A27-A nrPDB 46 2e-05 2YW9-A nrPDB 44 5e-05 3E9N-A nrPDB 44 5e-05 5YCX-A nrPDB 44 8e-05 3UCF-A nrPDB 41 4e-04 5CFZ-A nrPDB 38 0.004 4JQC-A nrPDB 38 0.004 1SNY-A nrPDB 37 0.006 4M89-A nrPDB 36 0.013 2P91-A nrPDB 36 0.015 3DWF-A nrPDB 36 0.020 4J3F-A nrPDB 35 0.039 1B15-A nrPDB 35 0.043 2QE0-A nrPDB 34 0.062 4Q9N-A nrPDB 33 0.13 4ALL-A nrPDB 32 0.22 4Z3K-A nrPDB 32 0.36 5TQV-A nrPDB 32 0.40 4HWK-A nrPDB 32 0.41 5PGZ-A nrPDB 31 0.56 2HRB-A nrPDB 29 1.7 1ENP-A nrPDB 29 1.7 2NTV-A nrPDB 29 1.7 3PRL-A nrPDB 29 2.0 5TY0-A nrPDB 29 2.6 4ZJU-A nrPDB 28 2.8 4NR0-A nrPDB 28 3.6 1EDZ-A nrPDB 28 3.7 3IC6-A nrPDB 28 4.0 3SLK-A nrPDB 28 4.1 2YIB-A nrPDB 28 4.3 5L51-A nrPDB 28 4.5 1OAA-A nrPDB 28 4.5 1Z45-A nrPDB 28 4.7 3U9L-A nrPDB 27 7.4 2UVV-A nrPDB 27 8.4 1W4Y-A nrPDB 27 10.0 >4CQL-A nrPDB Length = 261 Score = 529 bits (1363), Expect = e-151, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS Sbjct: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW Sbjct: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT Sbjct: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL Sbjct: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 ASEDSGYITGTSVEVTGGLFM Sbjct: 241 ASEDSGYITGTSVEVTGGLFM 261 >4JRO-A nrPDB Length = 271 Score = 200 bits (509), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 112/254 (44%), Positives = 157/254 (61%), Gaps = 10/254 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVA-ACDLDRAAAQETVRLLGGPGSKEGPPRG 67 L+ +A+VTG GIGR +++ LA EGA + + AA+ET +L+ G + Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVE------ 80 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A +A+V+ A +Q F R ++V+ AGIT+D L+ M ED+WD VI +N Sbjct: 81 -VEAMKANVAIAEDVDAFFKQAIERFGRV-DILVNNAGITRDNLLMRMKEDEWDDVININ 138 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKGTFL T+A ++ ++ G IIN++S+VG +GN GQ NY ASKAGVIGLT+T AREL Sbjct: 139 LKGTFLCTKAVSRTMMKQRA-GKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTAREL 197 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 GI N+V PGFI T MT K+ +K + + IP+G G ED+A+ V FLAS+ S Y Sbjct: 198 APRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKY 257 Query: 248 ITGTSVEVTGGLFM 261 ITG ++ V GG+ M Sbjct: 258 ITGQTLSVDGGMVM 271 >3FTP-A nrPDB Length = 270 Score = 192 bits (487), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 112/258 (43%), Positives = 154/258 (59%), Gaps = 11/258 (4%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + L +A+VTGA GIGRA+++ LA GA V A A+ G K+ Sbjct: 22 MDKTLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGI-----GAAFKQAG 76 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 G A +V++A A L+E F +V+V+ AGITQD+ + M +D+WD VI Sbjct: 77 LEGRGAVL--NVNDATAVDALVESTLKEFG-ALNVLVNNAGITQDQLAMRMKDDEWDAVI 133 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGS-IINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 NLK F +++A + ++ RG I+NI+S+VG GN GQ NYAA+KAGV G+T+ Sbjct: 134 DTNLKAVFRLSRAVLRPMMK--ARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRAL 191 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 ARE+G GI N V PGFI T MT+ +PQ+ + IP+G LG PED+A VAFLAS Sbjct: 192 AREIGSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASP 251 Query: 244 DSGYITGTSVEVTGGLFM 261 +GYITGT++ V GG+FM Sbjct: 252 QAGYITGTTLHVNGGMFM 269 >3OSU-A nrPDB Length = 246 Score = 191 bits (486), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 106/249 (42%), Positives = 158/249 (63%), Gaps = 10/249 (4%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG-NHAAF 72 ALVTGA GIGR+++++LA EG VA ++ A ++E + +E +G + A Sbjct: 7 ALVTGASRGIGRSIALQLAEEGYNVA---VNYAGSKEKAEAV----VEEIKAKGVDSFAI 59 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 QA+V++A + ++++V + F V+V+ AGIT+D L+ M E +WD VI NLKG F Sbjct: 60 QANVADADEVKAMIKEVVSQFG-SLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVF 118 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 Q A ++ G+IIN+SS+VG VGN GQ NY A+KAGVIGLT++AAREL GI Sbjct: 119 NCIQKATPQMLRQRS-GAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 193 RCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTS 252 N+V PGFI + MT + ++ +++ IP+ G D+A+ VAFLAS+ + YITG + Sbjct: 178 TVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQT 237 Query: 253 VEVTGGLFM 261 + V GG++M Sbjct: 238 IHVNGGMYM 246 >2UVD-A nrPDB Length = 246 Score = 188 bits (477), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 103/254 (40%), Positives = 155/254 (61%), Gaps = 10/254 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPRG 67 L+ +ALVTGA GIGRA+++ LA +GA V + A E V + GS Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGS------- 54 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + A +ADV+ A +++Q F + ++V+ AG+T+D L+ M E++WD VI N Sbjct: 55 DAIAVRADVANAEDVTNMVKQTVDVFGQV-DILVNNAGVTKDNLLMRMKEEEWDTVINTN 113 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG FL T+A ++ ++ G I+NI+S+VG GN GQ NY A+KAGVIGLT+T+A+EL Sbjct: 114 LKGVFLCTKAVSRFMMRQ-RHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKEL 172 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 I N++ PGFIAT MT + + + ++ ++IP G+ +D+A+ V F AS+ S Y Sbjct: 173 ASRNITVNAIAPGFIATDMTDVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKY 232 Query: 248 ITGTSVEVTGGLFM 261 ITG ++ V GG+ M Sbjct: 233 ITGQTLNVDGGMVM 246 >2HQ1-A nrPDB Length = 247 Score = 184 bits (468), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 104/260 (40%), Positives = 147/260 (56%), Gaps = 20/260 (7%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATV------AACDLDRAAAQETVRLLGGPGSK 61 +L+ A+VTG+ G+G+A++ +L GA + A+ LD A E + G Sbjct: 2 QLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLD--ATAEEFKAAGI---- 55 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWD 121 N + DV +++ F R ++V+ AGIT+D +L MSE DWD Sbjct: 56 ------NVVVAKGDVKNPEDVENMVKTAMDAFGRI-DILVNNAGITRDTLMLKMSEKDWD 108 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 V+ NLK +L T+A ++ ++ G IINI+SI G +GN GQ NYAASKAG+IG T+ Sbjct: 109 DVLNTNLKSAYLCTKAVSKIMLKQKS-GKIINITSIAGIIGNAGQANYAASKAGLIGFTK 167 Query: 182 TAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 + A+E GI CN+V PG I T MT +P KV + IP+ G PE+VA+VV FLA Sbjct: 168 SIAKEFAAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLA 227 Query: 242 SEDSGYITGTSVEVTGGLFM 261 S+DS YITG + + GGL M Sbjct: 228 SDDSNYITGQVINIDGGLVM 247 >4NBV-A nrPDB Length = 246 Score = 183 bits (464), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 104/252 (41%), Positives = 151/252 (59%), Gaps = 9/252 (3%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L+ +A++TGA +GIG A + R A +GA V CD+ A +E ++ Sbjct: 2 KLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAA-------ARLAATGA 54 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 +A++ DV+ ++ V A R ++V+ AGIT+D L M+E +D VI VN Sbjct: 55 TVSAYRVDVTRRDEVDAMVAAVLAAHQRV-DILVNNAGITKDARLAKMTEAQFDAVIDVN 113 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG F QA A + G +G I+N SS+VG GN GQTNYAASK GVIG T+T AREL Sbjct: 114 LKGVFNCAQAVAGLMTEQG-KGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWAREL 172 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 G G+R N+V PGF+ T + Q VP KV+D +T + L +P ++A + AFLAS+D+ Y Sbjct: 173 GPKGVRVNAVCPGFVNTEILQTVPDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASY 232 Query: 248 ITGTSVEVTGGL 259 + G ++E +GG+ Sbjct: 233 VNGVAIEASGGM 244 >2PNF-A nrPDB Length = 248 Score = 180 bits (456), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 102/260 (39%), Positives = 153/260 (58%), Gaps = 16/260 (6%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATV----AACDLDRAAAQETVRLLGGPGS 60 ++ +L+ ++LVTG+ GIGRA++ +LA G+TV + + +A A+E G Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVK-- 58 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 G ++ S +A + V ++V+ AGIT+D+ L MS DW Sbjct: 59 ----AHGVEMNLLSEESINKAFEEIYNLVDGI-----DILVNNAGITRDKLFLRMSLLDW 109 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 ++V+ VNL GTFLVTQ + + ++ G I+NISS+VG GNVGQ NY+ +KAG+IG T Sbjct: 110 EEVLKVNLTGTFLVTQNSLRKMIKQRW-GRIVNISSVVGFTGNVGQVNYSTTKAGLIGFT 168 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 ++ A+EL + N+V PGFI T MT + +++ K E IP+G G PE+VA+VV FL Sbjct: 169 KSLAKELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFL 228 Query: 241 ASEDSGYITGTSVEVTGGLF 260 SE + YITG + V GG+F Sbjct: 229 CSELASYITGEVIHVNGGMF 248 >4BO1-A nrPDB Length = 269 Score = 176 bits (446), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 101/253 (39%), Positives = 149/253 (58%), Gaps = 9/253 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +ALVTGA GIG+A+++ L GA V + A++ L G EG Sbjct: 25 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGV-EG----- 78 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A DVS + LE +Q +P +VV+ AGIT+D L+ M +D+W V+ NL Sbjct: 79 -AGLVLDVSSDESVAATLEHIQQHLGQPL-IVVNNAGITRDNLLVRMKDDEWFDVVNTNL 136 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 + +++A + + + G IINI S+VG +GN GQTNYAA+KAG+ G T+ ARE+G Sbjct: 137 NSLYRLSKAVLRGM-TKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVG 195 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 I N+V PGFI T MT+++P+ + + IP+G LG E++A VV FLAS+ + Y+ Sbjct: 196 SRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYV 255 Query: 249 TGTSVEVTGGLFM 261 TG +V V GG++M Sbjct: 256 TGATVPVNGGMYM 268 >4NBT-A nrPDB Length = 240 Score = 175 bits (444), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 99/254 (38%), Positives = 146/254 (57%), Gaps = 20/254 (7%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L +A++TG G+G+A+++ A EGA V A DL G + P Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDL-------------GDLTYSHP--- 46 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 N +V++ + V + + ++V+ AGIT+D M+E WD VI VN Sbjct: 47 NVEGMYLNVTDVTGVEKFYQSVIDKYGKI-DILVNNAGITKDAMTRKMTEAQWDAVIDVN 105 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG F +T+ + +NG GSIINISS+VG GN+GQ NYAA+KAGVIGLT T A+E Sbjct: 106 LKGVFNLTRLVGPQMQTNGY-GSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEF 164 Query: 188 GRHG--IRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 G +R N++ PG+I T + + VPQ ++DK + + LG PE++A V FLAS+D+ Sbjct: 165 ALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDA 224 Query: 246 GYITGTSVEVTGGL 259 Y+TG ++ V GG+ Sbjct: 225 SYVTGQTINVNGGM 238 >4KMS-A nrPDB Length = 249 Score = 175 bits (443), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 99/251 (39%), Positives = 143/251 (56%), Gaps = 12/251 (4%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +A+VTG GIG+A ++ L +G TV A A + + G +K Sbjct: 10 SEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTK--------C 61 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 AD E R A +++++ F +P S++V+ AGIT+D+ L MS DW+ VI VNL Sbjct: 62 WNVADFEECRQA---VKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNS 118 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F ++ + + + N G I+NISSI + G VGQTNY+A+KAG+IG T+ ARE Sbjct: 119 CFNMSSSVMEQM-RNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASK 177 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 I N + PG+IAT M VP+ V+ KI IP LG PE++A VAFL E++G+ITG Sbjct: 178 NITVNCIAPGYIATEMVGAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITG 237 Query: 251 TSVEVTGGLFM 261 ++ + GG M Sbjct: 238 ETISINGGHNM 248 >4DMM-A nrPDB Length = 269 Score = 174 bits (441), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 112/254 (44%), Positives = 153/254 (60%), Gaps = 12/254 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L +ALVTGA GIGRA+++ LA GA VA A A + V + G Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVV------AAIAAAGGE 79 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A +ADVS+ L V + R V+V+ AGIT+D LL M DDW V+ +NL Sbjct: 80 AFAVKADVSQESEVEALFAAVIERWGRL-DVLVNNAGITRDTLLLRMKRDDWQSVLDLNL 138 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 G FL ++AAA+ ++ G IINI+S+VG++GN GQ NY+A+KAGVIGLT+T A+EL Sbjct: 139 GGVFLCSRAAAKIMLKQRS-GRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELA 197 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASED-SGY 247 GI N+V PGFIAT MT ++ +K+ E+IP+G G+ +VA VV FLA++ + Y Sbjct: 198 SRGITVNAVAPGFIATDMTSELA---AEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAY 254 Query: 248 ITGTSVEVTGGLFM 261 ITG + + GGL M Sbjct: 255 ITGQVINIDGGLVM 268 >2PH3-A nrPDB Length = 245 Score = 174 bits (441), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 103/246 (41%), Positives = 148/246 (60%), Gaps = 7/246 (2%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 AL+TGA GIGRA+++RLA +G +A + +E + + G P A Sbjct: 4 ALITGASRGIGRAIALRLAEDGFALA---IHYGQNREKAEEVAEEARRRGSPL--VAVLG 58 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 A++ EA AA L+ Q ++V + AGIT+D L+ M ++DW+ V+ NL F Sbjct: 59 ANLLEAEAATALVHQAAEVLGGLDTLV-NNAGITRDTLLVRMKDEDWEAVLEANLSAVFR 117 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 T+ A + L+ G I+NI+S+VG +GN GQ NY ASKAG+IG T+ A+E + GI Sbjct: 118 TTREAVK-LMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGIT 176 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSV 253 N+V PGFI T MT+++PQ+V + + IP G G PE+VA+ VAFL SE +GYITG ++ Sbjct: 177 VNAVAPGFIETEMTERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTL 236 Query: 254 EVTGGL 259 V GGL Sbjct: 237 CVDGGL 242 >3RSH-A nrPDB Length = 251 Score = 172 bits (436), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 97/259 (37%), Positives = 145/259 (55%), Gaps = 13/259 (5%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 SQ N L +ALVTGA GIG+A++ LA GA V + AQ LG G Sbjct: 5 SQFMN-LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK-- 61 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 +V+ + +L+ + F ++V+ AGIT+D L+ M E++W Sbjct: 62 --------GMALNVTNPESIEAVLKAITDEFG-GVDILVNNAGITRDNLLMRMKEEEWSD 112 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 ++ NL F +++A + ++ +G IIN+ S+VG +GN GQ NYAA+KAGVIG T++ Sbjct: 113 IMETNLTSIFRLSKAVLRGMMKK-RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKS 171 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 ARE+ G+ N+V PGFI T MT+ + + +P G LGDP ++A VAFLAS Sbjct: 172 MAREVASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVPAGRLGDPREIASAVAFLAS 231 Query: 243 EDSGYITGTSVEVTGGLFM 261 ++ YITG ++ V GG++M Sbjct: 232 PEAAYITGETLHVNGGMYM 250 >2C07-A nrPDB Length = 285 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 93/249 (37%), Positives = 143/249 (57%), Gaps = 9/249 (3%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 + +ALVTGAG GIGR ++ LA + V + + V + G + + Sbjct: 44 NKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYES-------S 96 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 + DVS+ ++ ++ + ++V+ AGIT+D L M D+W+ V+ NL Sbjct: 97 GYAGDVSKKEEISEVINKI-LTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNS 155 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F +TQ ++ +++N G IINISSIVG GNVGQ NY++SKAGVIG T++ A+EL Sbjct: 156 LFYITQPISKRMINNRY-GRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASR 214 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 I N++ PGFI++ MT K+ +++ I IP G +G PE+VA++ FL+S+ SGYI G Sbjct: 215 NITVNAIAPGFISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYING 274 Query: 251 TSVEVTGGL 259 + GGL Sbjct: 275 RVFVIDGGL 283 >4M8S-A nrPDB Length = 248 Score = 171 bits (434), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 101/256 (39%), Positives = 147/256 (57%), Gaps = 17/256 (6%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATV---AACDLDRAAAQETVRLLGGPGSKEGPP 65 L +ALVTGA GIG A++ LA GA V A + AA E + GG G Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRV---- 61 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + +E L+ ++ F + ++V+ AGIT+D L+ M E++WD ++ Sbjct: 62 --------LNSAEPETVENLIADIEKTFGKL-DILVNNAGITRDNLLMRMKEEEWDDIMQ 112 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VNLK F ++A + ++ G IINI+S+VG +GN GQTNYAA+KAG+IG +++ AR Sbjct: 113 VNLKSVFRASKAVLRGMMKQRA-GRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAR 171 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 E+G GI N V PGFI T MT+ +P++ T +G GD +D+AD V FLAS+ + Sbjct: 172 EVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQA 231 Query: 246 GYITGTSVEVTGGLFM 261 YITG ++ V GG+ M Sbjct: 232 KYITGQTLHVNGGMLM 247 >3LYL-A nrPDB Length = 247 Score = 171 bits (432), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 99/253 (39%), Positives = 148/253 (58%), Gaps = 9/253 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L +ALVTGA GIG V+ LA +GATV +A+A++ + G K RG Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFK---ARG- 58 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 ++S+ + + +++A + ++V+ AGIT+D ++ MSED+W VI NL Sbjct: 59 ---LVLNISDIESIQNFFAEIKAE-NLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNL 114 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F +++ + ++ G II+I S+VG GN GQTNY A+KAGVIG +++ A E+ Sbjct: 115 SSIFRMSKECVRGMMKKRW-GRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVA 173 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 I N V PGFIAT MT K+ + I IP G +G+P+D+A VAFLASE++ YI Sbjct: 174 SRNITVNVVAPGFIATDMTDKLTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYI 233 Query: 249 TGTSVEVTGGLFM 261 TG ++ V GG++M Sbjct: 234 TGQTLHVNGGMYM 246 >2CDH-G nrPDB Length = 244 Score = 170 bits (431), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 106/251 (42%), Positives = 146/251 (58%), Gaps = 11/251 (4%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S + +VTGA GIG+A+++ L G V A A E V SK+ G A Sbjct: 1 SPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEV-------SKQIEAYGGQA 53 Query: 71 -AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 F DVS+ +++ + VVV+ AGIT+D L+ M + WD+VI +NL Sbjct: 54 ITFGGDVSKEADVEAMMKTAIDAWG-TIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLT 112 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGR 189 G FL TQAA + ++ +G IINI+S+VG +GN+GQ NYAA+KAGVIG ++TAARE Sbjct: 113 GVFLCTQAATKIMMKK-RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGAS 171 Query: 190 HGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA-SEDSGYI 248 I N V PGFIA+ MT K+ + + KI IP+G G PE+VA +V FLA S + YI Sbjct: 172 RNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYI 231 Query: 249 TGTSVEVTGGL 259 TG + + GG+ Sbjct: 232 TGQAFTIDGGI 242 >1Q7C-A nrPDB Length = 244 Score = 169 bits (429), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 94/249 (37%), Positives = 144/249 (57%), Gaps = 12/249 (4%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +ALVTGA GIGRA++ LA GA V AQ LG G Sbjct: 7 IALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGK----------GL 56 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 +V++ + +LE+++A F ++V+ AGIT+D L+ M +++W+ +I NL F Sbjct: 57 MLNVTDPASIESVLEKIRAEFG-EVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVF 115 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 +++A +A++ G II I S+VG +GN GQ N+AA+KAG+IG +++ ARE+ GI Sbjct: 116 RLSKAVMRAMMKK-RHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGI 174 Query: 193 RCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTS 252 N V PGFI T MT+ + I +P G LG +++A+ VAFLAS+++ YITG + Sbjct: 175 TVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGET 234 Query: 253 VEVTGGLFM 261 + V GG++M Sbjct: 235 LHVNGGMYM 243 >3WOH-A nrPDB Length = 251 Score = 167 bits (424), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 107/263 (40%), Positives = 152/263 (57%), Gaps = 30/263 (11%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQET---VRLLGGPGSKEGP 64 L +ALVTG G+GRA+++RLA +GA VA + D ++A+ET + LGG Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTAR---- 64 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSR------PPSVVVSCAGITQDEFLLHMSED 118 +++ DVS+A EQV C P ++V+ AGI +D + ++ Sbjct: 65 ------SYRCDVSDA-------EQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDE 111 Query: 119 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 D+D V+ NLKG FL +A + GSIINISS+ G G+ GQ NYA++KAG+IG Sbjct: 112 DYDAVMNTNLKGAFLFIKACYFGFIRKRS-GSIINISSVSGVFGSAGQANYASAKAGLIG 170 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVA 238 LT++ A+EL +RCN+V PG IAT MTQ + K + +PM G P++VA +VA Sbjct: 171 LTKSIAKELAERNVRCNAVAPGLIATDMTQDLVDD--SKRLDPVPMRRFGRPDEVAGLVA 228 Query: 239 FLASEDSGYITGTSVEVTGGLFM 261 FLA ++S YITG V V GG+ M Sbjct: 229 FLAGDESSYITGQVVCVDGGMAM 251 >3F9I-A nrPDB Length = 249 Score = 163 bits (412), Expect = 8e-41, Method: Compositional matrix adjust. Identities = 95/248 (38%), Positives = 143/248 (57%), Gaps = 16/248 (6%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 +L+TGA SGIG A++ L G+ V + + +E ++ LG + N+ Sbjct: 17 SLITGASSGIGSAIARLLHKLGSKV----IISGSNEEKLKSLGNA------LKDNYTIEV 66 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 +++ L+ + + ++V AGIT D + M + D+DKVI +NLK F+ Sbjct: 67 CNLANKEECSNLISK-----TSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFI 121 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 + + A + ++ G IINISSIVG GN GQ NY ASKAG+IG+T++ + E+ GI Sbjct: 122 LNREAIKKMIQKR-YGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGIT 180 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSV 253 N+V PGFI + MT K+ +K + I + IP+G G PEDVA VAFLAS ++ YITG ++ Sbjct: 181 VNAVAPGFIKSDMTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTL 240 Query: 254 EVTGGLFM 261 V GG+ M Sbjct: 241 HVNGGMLM 248 >4K6F-A nrPDB Length = 255 Score = 161 bits (407), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 98/263 (37%), Positives = 151/263 (57%), Gaps = 11/263 (4%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGA-TVAACDLDRAAAQETVRLLGGPG 59 MA + + +A+VTG G+G AVS+RL G V + A + + G Sbjct: 1 MAHHHHHHMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAG 60 Query: 60 SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD 119 R HA + DV++ + + +E++ P ++V+ AGIT+D L + + + Sbjct: 61 ------REFHA-YPVDVADHDSCQQCIEKIVRDVG-PVDILVNNAGITRDMTLRKLDKVN 112 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 WD VI NL F +T+ +V G G I+NISS+ G G+VGQTNYAA+KAG+ G Sbjct: 113 WDAVIRTNLDSVFNMTKPVCDGMVERGW-GRIVNISSVNGSKGSVGQTNYAAAKAGMHGF 171 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVD-KITEMIPMGHLGDPEDVADVVA 238 T++ A E+ R G+ N+V PG++AT M +PQ ++D KI IP G LG PE+VA +VA Sbjct: 172 TKSLALEIARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVA 231 Query: 239 FLASEDSGYITGTSVEVTGGLFM 261 +L SE++G++TG+++ + GG M Sbjct: 232 YLCSEEAGFVTGSNIAINGGQHM 254 >5CDY-A nrPDB Length = 244 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 93/249 (37%), Positives = 138/249 (55%), Gaps = 12/249 (4%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +ALVTGA GIGRA++ L GA V A+ LG G Sbjct: 7 IALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGK----------GL 56 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 +V + + +L ++A F ++V+ AGIT+D L+ M +D+W +I NL F Sbjct: 57 MLNVVDPTSIDTVLATIRAEFG-EVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVF 115 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 +++A +A++ G II I S+VG +GN GQ NYAA+KAGVIG +++ ARE+ GI Sbjct: 116 RLSKAVMRAMMKKRF-GRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGI 174 Query: 193 RCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTS 252 N V PGFI T MT+ + I +P LGD +++A VAFLAS+++ YI+G + Sbjct: 175 TVNVVAPGFIETDMTRTLTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGET 234 Query: 253 VEVTGGLFM 261 + V GG++M Sbjct: 235 LHVNGGMYM 243 >4RZH-A nrPDB Length = 247 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 105/255 (41%), Positives = 147/255 (57%), Gaps = 14/255 (5%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L + +ALVTGA GIG+A ++ LA G V + A + V E G Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAV-------VAEIIANGG 56 Query: 69 HA-AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A A QA+V+ A L++ FSR V+V+ AGIT+D LL M +DW VI +N Sbjct: 57 EAIAVQANVANADEVDQLIKTTLDKFSRI-DVLVNNAGITRDTLLLRMKLEDWQAVIDLN 115 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L G FL T+A ++ ++ G IINI+S+ G +GN GQ NY+A+KAGVIG T+T A+EL Sbjct: 116 LTGVFLCTKAVSKLMLKQKS-GRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKEL 174 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASED-SG 246 G+ N+V PGFIAT MT+ + + I + IP+ G PE+VA + FLA++ + Sbjct: 175 ASRGVTVNAVAPGFIATDMTENLN---AEPILQFIPLARYGQPEEVAGTIRFLATDPAAA 231 Query: 247 YITGTSVEVTGGLFM 261 YITG + V GG+ M Sbjct: 232 YITGQTFNVDGGMVM 246 >5VT6-A nrPDB Length = 269 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 93/250 (37%), Positives = 141/250 (56%), Gaps = 9/250 (3%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +A VTG G+G A+S RL G VA +R T + E + A+ Sbjct: 27 VAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLM------HERDAGRDFKAY 80 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 DV++ + E+V A F + V+++ AGIT+D + M++ DWD V+ +L F Sbjct: 81 AVDVADFESCERCAEKVLADFGKV-DVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMF 139 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 VT+ +V G I+NI S+ G G GQ NYA++KAG+ G T+T A E + GI Sbjct: 140 NVTKQFIAGMVERRF-GRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGI 198 Query: 193 RCNSVLPGFIATPMTQKVPQKVVD-KITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 N+V PG++AT M + VPQ V++ KI IP+G LG P++VA ++AFL S+D+G++TG Sbjct: 199 TVNTVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGA 258 Query: 252 SVEVTGGLFM 261 + + GG+ M Sbjct: 259 DLAINGGMHM 268 >2NM0-A nrPDB Length = 253 Score = 154 bits (389), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 135/247 (54%), Gaps = 20/247 (8%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG GIG A++ A G VA + G P A + Sbjct: 25 LVTGGNRGIGLAIARAFADAGDKVAIT------------------YRSGEPPEGFLAVKC 66 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 D+++ ++++ P V+++ AG+T+D+ L+ MSE+D+ V+ NL GTF V Sbjct: 67 DITDTEQVEQAYKEIEETHG-PVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRV 125 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 + A +A++ +G ++ ISS+VG +G+ GQ NYAASKAG++G ++ ARELG I Sbjct: 126 VKRANRAML-RAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITF 184 Query: 195 NSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVE 254 N V PGF+ T MT+ + + I +P+G PE++A V FLAS+D+ YITG + Sbjct: 185 NVVAPGFVDTDMTKVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIP 244 Query: 255 VTGGLFM 261 V GGL M Sbjct: 245 VDGGLGM 251 >3VZS-A nrPDB Length = 257 Score = 150 bits (378), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 93/253 (36%), Positives = 139/253 (54%), Gaps = 16/253 (6%) Query: 13 LALVTGAGSGIGRAVSVRLAGEG-ATVAACDLD---RAAAQETVRLLGGPGSKEGPPRGN 68 +A VTG GIG A+ RLA +G VA C + R E + LG + Sbjct: 16 IAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGF----------D 65 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A + +V++ + + ++V++ V+++ AGIT+D M+ DWD VI NL Sbjct: 66 FIASEGNVADWDSTKTAFDKVKSEVGEV-DVLINNAGITRDVVFRKMTRADWDAVIDTNL 124 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F VT+ + G G I+NISS+ G+ G GQTNY+ +KAG+ G T A+E+ Sbjct: 125 TSLFNVTKQVIDGMADRGW-GRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVA 183 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 G+ N+V PG+IAT M + + Q V+DKI IP+ LG PE++A + A+L+SE+SG+ Sbjct: 184 TKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFS 243 Query: 249 TGTSVEVTGGLFM 261 TG + GGL M Sbjct: 244 TGADFSLNGGLHM 256 >3EMK-A nrPDB Length = 246 Score = 148 bits (373), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 90/248 (36%), Positives = 136/248 (54%), Gaps = 12/248 (4%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 ALVTGA G+G A++ L +GA V +E LG F Sbjct: 10 ALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGE----------RIFVFP 59 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 A++S+ A + L ++ + ++V+ AGIT+D + MS++DWD V+ VNL F Sbjct: 60 ANLSDREAVKALGQKAEEEMG-GVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFN 118 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 +T+ ++ G IINI+SIVG GN GQ NY ASKAG+IG +++ A+E+ + Sbjct: 119 LTRELTHPMMRR-RNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVT 177 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSV 253 N + PGFI + MT K+ +K D I IPM +G D+A V +LAS+++ Y+TG ++ Sbjct: 178 VNCIAPGFIESAMTGKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTL 237 Query: 254 EVTGGLFM 261 V GG+ M Sbjct: 238 HVNGGMAM 245 >1UZM-A nrPDB Length = 247 Score = 148 bits (373), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 96/250 (38%), Positives = 139/250 (55%), Gaps = 26/250 (10%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG GIG A++ RLA +G VA G P+G + Sbjct: 19 LVTGGNRGIGLAIAQRLAADGHKVAVTH-----------------RGSGAPKGLFGV-EV 60 Query: 75 DVSEARA---ARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 DV+++ A A +E+ Q P V+VS AG++ D FL+ M+E+ ++KVI NL G Sbjct: 61 DVTDSDAVDRAFTAVEEHQG----PVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGA 116 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHG 191 F V Q A++++ N G +I I S+ G G Q NYAASKAGVIG+ ++ AREL + Sbjct: 117 FRVAQRASRSMQRNKF-GRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKAN 175 Query: 192 IRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 + N V PG+I T MT+ + +++ + IP +G P +VA VV+FLASED+ YI+G Sbjct: 176 VTANVVAPGYIDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGA 235 Query: 252 SVEVTGGLFM 261 + V GG+ M Sbjct: 236 VIPVDGGMGM 245 >3GRP-A nrPDB Length = 266 Score = 147 bits (372), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 90/254 (35%), Positives = 139/254 (54%), Gaps = 12/254 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L ALVTGA GIG A++ +GA V +E LG Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGK---------- 73 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + F A++S+ ++ + L E + ++V+ AGIT+D + M + DWD V+AVN Sbjct: 74 DVFVFSANLSDRKSIKQLAEVAEREME-GIDILVNNAGITRDGLFVRMQDQDWDDVLAVN 132 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L +T+ +++ G IINI+SIVG VGN GQTNY A+KAG+IG ++ A+E+ Sbjct: 133 LTAASTLTRELIHSMMRRRY-GRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEI 191 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 I N + PGFI + MT K+ +K + I MIPM +G E++A +LAS+++ Y Sbjct: 192 ASRNITVNCIAPGFIKSAMTDKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAY 251 Query: 248 ITGTSVEVTGGLFM 261 +TG ++ + GG+ M Sbjct: 252 LTGQTLHINGGMAM 265 >3EZL-A nrPDB Length = 256 Score = 145 bits (367), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 91/253 (35%), Positives = 137/253 (54%), Gaps = 16/253 (6%) Query: 13 LALVTGAGSGIGRAVSVRLAGEG-ATVAACDLD---RAAAQETVRLLGGPGSKEGPPRGN 68 +A VTG GIG ++ RL +G VA C + R E + LG + Sbjct: 15 IAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGF----------D 64 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A + +V + + + ++V+A V+V+ AGIT+D M+ +DW VI NL Sbjct: 65 FYASEGNVGDWDSTKQAFDKVKAEVGEI-DVLVNNAGITRDVVFRKMTREDWQAVIDTNL 123 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F VT+ +V G G IINISS+ G+ G GQTNY+ +KAG+ G T + A+E+ Sbjct: 124 TSLFNVTKQVIDGMVERGW-GRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVA 182 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 G+ N+V PG+I T M + + V++KI IP+ LG P+++ +VA+LASE+SG+ Sbjct: 183 TKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFS 242 Query: 249 TGTSVEVTGGLFM 261 TG + GGL M Sbjct: 243 TGADFSLNGGLHM 255 >4RZI-B nrPDB Length = 240 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 97/252 (38%), Positives = 135/252 (53%), Gaps = 24/252 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L + +VTG GIG A+ L GA VA DL + +G GN Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDL----------------ATDG---GN 46 Query: 69 HAAFQ--ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 A A+V++ + ++ P VV+ AGIT+D F ++ DWD V+ V Sbjct: 47 TEALGVVANVTDLESMTAAAAEITDKLG-PVYGVVANAGITKDNFFPKLTPADWDAVLNV 105 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 NLKG + + + GSI+ ISSI G+ GNVGQTNY+A+KAGVIG+ ++ ARE Sbjct: 106 NLKGVAYSIKPFIEGMYERKA-GSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLARE 164 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE-DS 245 R+G+R N+V PGFI T MT + + + +KIT+ IP G PE++A VAFL S S Sbjct: 165 GARYGVRANAVAPGFIDTEMTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVAS 224 Query: 246 GYITGTSVEVTG 257 Y+TG + V G Sbjct: 225 SYVTGEVLRVNG 236 >5OVL-A nrPDB Length = 300 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 92/247 (37%), Positives = 136/247 (55%), Gaps = 20/247 (8%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG GIG A++ RLA +G VA T R G P G Q Sbjct: 72 LVTGGNRGIGLAIARRLAADGHKVAV----------THRGSGAPDDLFG--------VQC 113 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DV+++ A ++V+ P V+V+ AGI++D FL+ M+E+ +++VI NL G F Sbjct: 114 DVTDSAAVDRAFKEVEE-HQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRC 172 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 Q A++ + G II I S+ G G Q NYAA+KAG+IG+ ++ +REL + G+ Sbjct: 173 AQRASRTMQRKRF-GRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTA 231 Query: 195 NSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVE 254 N V PG+I T MT+ + +++ + IP +G E+VA V+FLASED+ YI G + Sbjct: 232 NVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 291 Query: 255 VTGGLFM 261 V GG+ M Sbjct: 292 VDGGMGM 298 >5OVJ-A nrPDB Length = 256 Score = 141 bits (355), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 92/247 (37%), Positives = 136/247 (55%), Gaps = 20/247 (8%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG GIG A++ RLA +G VA T R G P G Q Sbjct: 28 LVTGGNRGIGLAIARRLAADGHKVAV----------THRGSGAPDDLFG--------VQC 69 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DV+++ A ++V+ P V+V+ AGI++D FL+ M+E+ +++VI NL G F Sbjct: 70 DVTDSAAVDRAFKEVEE-HQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRC 128 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 Q A++ + G II I S+ G G Q NYAA+KAG+IG+ ++ +REL + G+ Sbjct: 129 AQRASRTMQRKRF-GRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTA 187 Query: 195 NSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVE 254 N V PG+I T MT+ + +++ + IP +G E+VA V+FLASED+ YI G + Sbjct: 188 NVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 247 Query: 255 VTGGLFM 261 V GG+ M Sbjct: 248 VDGGMGM 254 >3RWB-A nrPDB Length = 247 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 90/253 (35%), Positives = 133/253 (52%), Gaps = 12/253 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL ALVTGA GIG+A++ RLA +GATV D++ A+ +G Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKAR------- 55 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A AD+S+ + + L ++QA + ++V+ A I + D W K+I VN Sbjct: 56 ---AIAADISDPGSVKALFAEIQA-LTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVN 111 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L GTF+VT+A + + G G +I+I+S G Y A+K GVIG T+ A EL Sbjct: 112 LTGTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATEL 171 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMI-PMGHLGDPEDVADVVAFLASEDSG 246 G++ I N+V PG I + + P EM+ M G PE +ADVV+FLAS+D+ Sbjct: 172 GKYNITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDAR 231 Query: 247 YITGTSVEVTGGL 259 +ITG ++ V G+ Sbjct: 232 WITGQTLNVDAGM 244 >4IIV-A nrPDB Length = 267 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 92/257 (35%), Positives = 132/257 (51%), Gaps = 10/257 (3%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAA-CDLDRAAAQETVRLLGGPGSKEG 63 Q+ S LVTGA GIGRA++ +LA +G + D A AQET+ + G Sbjct: 20 FQSNAMSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANG---- 75 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 GN DV+ R +LE A VV S AGI +D +S DDWD V Sbjct: 76 ---GNGRLLSFDVANREQCREVLEHEIAQHGAWYGVV-SNAGIARDAAFPALSNDDWDAV 131 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 I NL + V Q ++ G II +SS+ G +GN GQ NY+A+KAG+IG T+ Sbjct: 132 IHTNLDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKAL 191 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 A EL + I N + PG I T M + + + + + MIPM +G E+VA + ++L S+ Sbjct: 192 AIELAKRKITVNCIAPGLIDTGMIE-MEESALKEAMSMIPMKRMGQAEEVAGLASYLMSD 250 Query: 244 DSGYITGTSVEVTGGLF 260 +GY+T + + GG+ Sbjct: 251 IAGYVTRQVISINGGML 267 >1GEG-A nrPDB Length = 256 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 93/260 (35%), Positives = 136/260 (52%), Gaps = 19/260 (7%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +ALVTGAG GIG+A+++RL +G VA D + A A+ + G G+ A Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAG-------GHAVAV 56 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 + DVS+ +EQ + V+V+ AG+ + ++ + DKV +N+KG Sbjct: 57 KVDVSDRDQVFAAVEQARKTLGGF-DVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVI 115 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 QAA +A G G IIN S G VGN Y++SK V GLTQTAAR+L GI Sbjct: 116 WGIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGI 175 Query: 193 RCNSVLPGFIATPMTQKVPQKVVD-----------KITEMIPMGHLGDPEDVADVVAFLA 241 N PG + TPM ++ ++V + + + I +G L +PEDVA V++LA Sbjct: 176 TVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLA 235 Query: 242 SEDSGYITGTSVEVTGGLFM 261 S DS Y+TG S+ + GG+ Sbjct: 236 SPDSDYMTGQSLLIDGGMVF 255 >4IIN-A nrPDB Length = 271 Score = 136 bits (343), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 85/249 (34%), Positives = 134/249 (53%), Gaps = 12/249 (4%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 L+TGA GIG ++ LA G V A + ++ E +G AA Sbjct: 33 LITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALK-------NELEEKGYKAAVIK 85 Query: 75 DVSEARAARCLLEQVQACFSRP--PSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 +A + +E +Q S +V+ AG+ +D+ + M +D+ VI NL F Sbjct: 86 --FDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAF 143 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 + + A + + S GS++N++SI+G+ GN+GQTNY+ASK G+I ++++ A E I Sbjct: 144 IGCREALKVM-SKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNI 202 Query: 193 RCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTS 252 R NSV PGFI T M + ++ + IP+ LG ++VA+ VAFL S+ S YITG + Sbjct: 203 RFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGET 262 Query: 253 VEVTGGLFM 261 ++V GGL+M Sbjct: 263 LKVNGGLYM 271 >3OEC-A nrPDB Length = 317 Score = 134 bits (337), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 94/281 (33%), Positives = 151/281 (53%), Gaps = 39/281 (13%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAA------------QETVRL 54 NRL+ +A +TGA G GR +VRLA +GA + A DL R +ETVRL Sbjct: 42 NRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRL 101 Query: 55 LGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLH 114 + G + A QADV + + + ++++ A F ++VS GI+ ++ Sbjct: 102 VEEQGRRI-------IARQADVRDLASLQAVVDEALAEFGHI-DILVSNVGISNQGEVVS 153 Query: 115 MSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKA 174 +++ W ++ NL G + +A +++ G GS+I +SS VG G GQ++YAASK Sbjct: 154 LTDQQWSDILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKH 213 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPM-----------------TQKVPQKVVDK 217 GV GL + A E+GRH IR NSV PG + T M T++ ++ + Sbjct: 214 GVQGLMLSLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQ 273 Query: 218 ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 +T ++P+ + +PEDV++ VA+LAS+++ YI G ++ V GG Sbjct: 274 LT-LLPIPWV-EPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >4Z9Y-A nrPDB Length = 253 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 12/254 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +AL+TG +G+G+ +++ LA G + ++ ++T+ + G + Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNI--VEPKDTIEKVTALGRR------- 58 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 + AD+S L+E+ A F ++V+ AGI + E + SE +WD V+ +N+ Sbjct: 59 FLSLTADMSNVSGHAELVEKAVAEFGHV-DILVNNAGIIRREDAIEFSEKNWDDVMNLNI 117 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 K F ++Q A+ + G G IINI+S++ G + +Y ASK+ V+G+T+ A E Sbjct: 118 KSVFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWA 177 Query: 189 RHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 +HGI N++ PG++AT TQ++ ++ +I + IP G G P+D+ FLAS S Sbjct: 178 KHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASD 237 Query: 247 YITGTSVEVTGGLF 260 YI G ++ V GG Sbjct: 238 YINGYTIAVDGGWL 251 >4HP8-A nrPDB Length = 247 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 90/249 (36%), Positives = 133/249 (53%), Gaps = 17/249 (6%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 ALVTGA +G+G+A++V LA GA V R A ET+ ++ +K+G GN +A Sbjct: 12 ALVTGANTGLGQAIAVGLAAAGAEVVCAA--RRAPDETLDII----AKDG---GNASALL 62 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 D ++ AA+ A F ++V+ AGI + + SE DWD+V+ VNLK F Sbjct: 63 IDFADPLAAKDSF--TDAGFD----ILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFF 116 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 TQA A+ L++ G G ++NI+S++ G + +Y A+K GV GLT+ A E GI Sbjct: 117 TTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGIN 176 Query: 194 CNSVLPGFIATPMTQKVPQKVVDK--ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 N++ PG+I T T+ + I E IP G G ED+A FL+S + Y+ G Sbjct: 177 VNAIAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGA 236 Query: 252 SVEVTGGLF 260 + V GG Sbjct: 237 ILNVDGGWL 245 >1GEE-A nrPDB Length = 261 Score = 130 bits (327), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 84/262 (32%), Positives = 142/262 (54%), Gaps = 19/262 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAA---CDLDRA-AAQETVRLLGGPGS 60 + L + ++TG+ +G+G+++++R A E A V D A + E ++ +GG Sbjct: 1 MYKDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEA- 59 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 A + DV+ L++ F + V+++ AG+ MS DW Sbjct: 60 ---------IAVKGDVTVESDVINLVQSAIKEFGKL-DVMINNAGLENPVSSHEMSLSDW 109 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 +KVI NL G FL ++ A + V N +G++IN+SS+ K+ +YAASK G+ +T Sbjct: 110 NKVIDTNLTGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMT 169 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKV---PQKVVDKITEMIPMGHLGDPEDVADVV 237 +T A E GIR N++ PG I TP+ + P++ D + MIPMG++G+PE++A V Sbjct: 170 ETLALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRAD-VESMIPMGYIGEPEEIAAVA 228 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 A+LAS ++ Y+TG ++ GG+ Sbjct: 229 AWLASSEASYVTGITLFADGGM 250 >6NRP-A nrPDB Length = 263 Score = 130 bits (326), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 86/247 (34%), Positives = 134/247 (54%), Gaps = 12/247 (4%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDR-AAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 LVTG+ GIG+A++++LA G V R A A++ V+ + G N Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQ-------NSHYLM 80 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 DV+E + + +LEQ VV++ AG+T D +++ DWD+VI+ +L G + Sbjct: 81 FDVNERQTVQQILEQDVEQHGGFYGVVLN-AGLTHDGAFPALTDQDWDEVISTSLDGFYN 139 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 V + ++ G I+ +SS+ G +GN GQ NY+A+KAG+IG T+ A EL + I Sbjct: 140 VLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKIT 199 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSV 253 N V PG I T M V +V + +MIP+ +G ++VA VV FL S+++ Y+T + Sbjct: 200 VNCVAPGLIETEM---VTDEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVI 256 Query: 254 EVTGGLF 260 V GGL Sbjct: 257 SVNGGLI 263 >4CQM-B nrPDB Length = 244 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 85/244 (34%), Positives = 131/244 (53%), Gaps = 17/244 (6%) Query: 16 VTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQAD 75 V G GIGRAV+ +A +G +A R L G + G G+H AF D Sbjct: 14 VFGGSRGIGRAVAQLMARKGYRLAVI----------ARNLEGAKAAAGDLGGDHLAFSCD 63 Query: 76 VSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVT 135 V++ + E+++ R + +V+ AGI +D L+ +D + NL G+ L Sbjct: 64 VAKEHDVQNTFEELEKHLGRV-NFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 122 Query: 136 QAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCN 195 +AA + ++ GSI+N+ SIVG GN GQ+ Y+ASK G++G ++ A+E+ R IR N Sbjct: 123 KAAMRTMIQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 181 Query: 196 SVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEV 255 V PGF+ T MT+ + + + + + IP+G G+ +VA V FL +S YITG + V Sbjct: 182 VVAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 236 Query: 256 TGGL 259 GGL Sbjct: 237 DGGL 240 >5ITV-A nrPDB Length = 255 Score = 127 bits (319), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 86/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 L L+TG SGIG A G+ A V D+D A + VR KE R Sbjct: 4 NLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVR-------KENNDRL 56 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + Q D+++ A + +E F V+++ AGI + M DW+KV+ VN Sbjct: 57 HFV--QTDITDEAACQHAVESAVHTFG-GLDVLINNAGIEIVAPIHEMELSDWNKVLQVN 113 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L G FL+++ A + +++ G +G+IIN S+ G V Y ASK GV+ LT++ A + Sbjct: 114 LTGMFLMSKHALKHMLAAG-KGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDY 172 Query: 188 GRHGIRCNSVLPGFIATPMTQK--------VPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 +H IR N V PG I TP+ +K +++ + ++ P+ LG PE++A+V+ F Sbjct: 173 AKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLF 232 Query: 240 LASEDSGYITGTSVEVTGG 258 LAS+ S Y+TG+++ GG Sbjct: 233 LASDLSSYMTGSAITADGG 251 >5T5Q-A nrPDB Length = 247 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 82/261 (31%), Positives = 128/261 (49%), Gaps = 17/261 (6%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 M + +NR ++TGA GIGRA++ GA + DLDR LG P Sbjct: 3 MKFEFENRT----LVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPE- 57 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 A +AD S A A + F +V AGI Q + MS+ DW Sbjct: 58 -------RIATIKADASSADDAEKTVALAMERFGGI-DFLVPSAGIYQAKPFAEMSDADW 109 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 + I++NL G F + + A AL + SI+ ++S+ G +Y A+K ++ +T Sbjct: 110 HRTISINLDGVFYLCKRALPALKEDS---SIVTLASLAAYRGAYVNAHYGATKGAMVSMT 166 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 + +REL R N V PG I TPMT ++ + +D+ P+ LG P ++A V+AFL Sbjct: 167 RALSRELAPK-TRVNGVSPGIIETPMTSELLKTRMDETMTQTPLKRLGKPSEIASVIAFL 225 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 S + ++TG +++V GG++M Sbjct: 226 CSPAASFVTGETIQVNGGIYM 246 >3AUT-A nrPDB Length = 269 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 84/258 (32%), Positives = 135/258 (52%), Gaps = 11/258 (4%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + L+ + ++TG +G+GRA++VR E A V + +E + KE Sbjct: 9 MYTDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNE--EEALD-----AKKEVE 61 Query: 65 PRGNHAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 G A Q DV++ L++ F V+++ AG+ +S D+W+KV Sbjct: 62 EAGGQAIIVQGDVTKEEDVVNLVQTAIKEFGTL-DVMINNAGVENPVPSHELSLDNWNKV 120 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 I NL G FL ++ A + V N +G++IN+SS+ + +YAASK G+ +T+T Sbjct: 121 IDTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETL 180 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDK--ITEMIPMGHLGDPEDVADVVAFLA 241 A E GIR N++ PG + TP+ + V + + MIPMG++G PE+VA V AFLA Sbjct: 181 ALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLA 240 Query: 242 SEDSGYITGTSVEVTGGL 259 S + Y+TG ++ GG+ Sbjct: 241 SSQASYVTGITLFADGGM 258 >6CI9-A nrPDB Length = 259 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 90/259 (34%), Positives = 131/259 (50%), Gaps = 14/259 (5%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + L A+VTG GIGR ++ A G V ++ TV L G Sbjct: 1 SHMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGT---- 56 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCA--GITQDEFLLHMSEDDW 120 RG A +ADV++ AR V SR + + CA GI L ++ DD Sbjct: 57 ---RGKVTAVRADVTDPEDAR---RTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDI 110 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-GNVGQTNYAASKAGVIGL 179 ++V+ VN KGT + QAA QAL ++G G ++ SSI G + G G ++Y ASKA +G Sbjct: 111 EQVLGVNFKGTVYIVQAALQALTASG-HGRVVVTSSITGPITGYPGWSHYGASKAAQLGF 169 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 +TAA EL I N+VLPG I T ++ Q +D++ IP G LG D+ + F Sbjct: 170 LRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALF 229 Query: 240 LASEDSGYITGTSVEVTGG 258 A++++ Y+TG ++ V GG Sbjct: 230 FATDEAAYVTGQTLVVDGG 248 >3WTC-A nrPDB Length = 262 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 90/263 (34%), Positives = 132/263 (50%), Gaps = 21/263 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L +A VTGA GIG+A+++RLA +GA V D+ + ET +KE G Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAET--------AKEVEALGR 57 Query: 69 HA-AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A A AD+S R L ++V+ AGI Q + +L + + +K+ ++N Sbjct: 58 RAVALTADISNRDQFRSTLADAAKTLG-GLDIMVNNAGICQVKPILDIEPAEIEKIFSIN 116 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 ++G QAAA G +G IIN SI G G Y+A+K V LTQ+AA+EL Sbjct: 117 VQGVLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKEL 176 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVD-----------KITEMIPMGHLGDPEDVADV 236 GI NS PG + T M + +++ + K E I +G + +DVA Sbjct: 177 ASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGF 236 Query: 237 VAFLASEDSGYITGTSVEVTGGL 259 VA+L+S D+ Y+TG SV + GGL Sbjct: 237 VAYLSSSDADYMTGQSVLIDGGL 259 >2CFC-A nrPDB Length = 250 Score = 123 bits (309), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 93/252 (36%), Positives = 138/252 (54%), Gaps = 13/252 (5%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +A+VTGA SG G A++ R G VAA DL +ET R + + Sbjct: 2 SRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADV 61 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGIT--QDEFLLHMSE-DDWDKVIAVN 127 A + DV+ A AA +EQ A V+V+ AGIT + +LH + + +DKV+AVN Sbjct: 62 ADEGDVNAAIAAT--MEQFGAI-----DVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 ++G FL +A ++ G G I+NI+S+ V G++ Y SK V+ LT++ A + Sbjct: 115 VRGIFLGCRAVLPHMLLQGA-GVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDY 173 Query: 188 GRHGIRCNSVLPGFIATPMTQ-KVPQ-KVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 GIRCN+V PG I TPMTQ ++ Q ++ D++ IP +G VAD V FLA ED+ Sbjct: 174 AGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDA 233 Query: 246 GYITGTSVEVTG 257 Y+ G ++ + G Sbjct: 234 TYVNGAALVMDG 245 >3WYE-A nrPDB Length = 256 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 91/258 (35%), Positives = 136/258 (52%), Gaps = 19/258 (7%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +ALVTGAG GIG+A+++RL +G VA D + A A+ + G G+ A Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAG-------GHAVAV 56 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 + DVS+ +EQ + V+V+ AGI Q + LL ++E+D ++ +VN+ F Sbjct: 57 KVDVSDRDQVFAAVEQARKTLGGF-DVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVF 115 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 QAA +A G G IIN +SI G + Y+ +K V GLTQTAAR+L GI Sbjct: 116 FGIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGI 175 Query: 193 RCNSVLPGFIATPMTQKVPQKV-----------VDKITEMIPMGHLGDPEDVADVVAFLA 241 N PG + T M +++ ++ + + I +G PEDVA +V+FLA Sbjct: 176 TVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLA 235 Query: 242 SEDSGYITGTSVEVTGGL 259 S DS Y+TG S+ + GG+ Sbjct: 236 SPDSDYMTGQSLLIDGGM 253 >2O23-A nrPDB Length = 265 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 83/266 (31%), Positives = 134/266 (50%), Gaps = 27/266 (10%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 ++ +A++TG SG+G A + RL G+GA+ DL + + + LG N Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG-----------N 58 Query: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE------DDWD 121 + F ADV+ + + L + F R V V+CAGI ++ + +D+ Sbjct: 59 NCVFAPADVTSEKDVQTALALAKGKFGRV-DVAVNCAGIAVASKTYNLKKGQTHTLEDFQ 117 Query: 122 KVIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGV 176 +V+ VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G+ Sbjct: 118 RVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 177 Query: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVAD 235 +G+T AR+L GIR ++ PG TP+ +P+KV + + +P LGDP + A Sbjct: 178 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAH 237 Query: 236 VVAFLASEDSGYITGTSVEVTGGLFM 261 +V A ++ ++ G + + G + M Sbjct: 238 LVQ--AIIENPFLNGEVIRLDGAIRM 261 >1K2W-A nrPDB Length = 256 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 84/266 (31%), Positives = 134/266 (50%), Gaps = 24/266 (9%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL AL+TG+ GIGRA + EGA VA D++ AA+ T +G P + Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIG-PAA------- 53 Query: 68 NHAAFQADVSE-ARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 A DV++ A RC+ E + S ++V+ A + ++ ++ + +D++ A+ Sbjct: 54 --CAIALDVTDQASIDRCVAELLDRWGS--IDILVNNAALFDLAPIVEITRESYDRLFAI 109 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 N+ GT + QA A+A+++ G G IIN++S G+ G Y A+KA VI LTQ+A Sbjct: 110 NVSGTLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLN 169 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVD-----------KITEMIPMGHLGDPEDVAD 235 L RHGI N++ PG + V K D ++ +P G +G ED+ Sbjct: 170 LIRHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTG 229 Query: 236 VVAFLASEDSGYITGTSVEVTGGLFM 261 + FLA+ ++ YI + V GG +M Sbjct: 230 MAIFLATPEADYIVAQTYNVDGGNWM 255 >5B1Y-A nrPDB Length = 270 Score = 116 bits (291), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 90/262 (34%), Positives = 135/262 (51%), Gaps = 23/262 (8%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATV-----AACDLDRAAAQETVRLLGGPGSK 61 + + + ALVTG GIGRA +R A EG +V + DL A+E RL GS Sbjct: 19 SHMETTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRL----GSP 74 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWD 121 E + DV + + + +V +V+V+ AG+ Q + S +W+ Sbjct: 75 EA------YTVRVDVGDPDSVTEMSSRVGELIPHL-NVLVNAAGVLQLGGIEETSISEWE 127 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNV-GQTNYAASKAGVIGLT 180 + + VNL G +LVT+ + SI+N++SI G+ GNV Y+ASKAGVIGLT Sbjct: 128 ETLRVNLTGVYLVTKLLLPL-LRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLT 186 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQK---VPQKVVDKITEMIPMGHLGDPEDVADVV 237 + A +L +GIR N+V P F+ T MT+ P+K ++I + P+ + PEDVA+ + Sbjct: 187 KRLAVQLAGYGIRVNAVAPSFVETDMTRSFLDTPEK-RERIASLHPLKIILKPEDVAEAI 245 Query: 238 AFLAS-EDSGYITGTSVEVTGG 258 FLA S ITG + + G Sbjct: 246 LFLADPRRSRGITGHVLSINAG 267 >5O3Z-A nrPDB Length = 263 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/261 (31%), Positives = 133/261 (50%), Gaps = 18/261 (6%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +A+V G G +G + LA G VA DL+ + A RL S+ G R F Sbjct: 8 VAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNAN---RLADTINSRYGAGRA--YGF 62 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 + D ++ + L V F R +V S AG+ + + D+D + VNL G F Sbjct: 63 KVDATDEASVEALARAVDETFGRADLLVYS-AGVAKAAPITQFRLTDFDLSLQVNLVGYF 121 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 L ++ ++ ++ +G +G II I+S GKVG+ + Y+A+K G +GLTQ+ A +L +GI Sbjct: 122 LCSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGI 181 Query: 193 RCNSVLPG-FIATPMTQKV-----------PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 +S++ G + +PM Q + P++V + +P+ D +DV +V+ F Sbjct: 182 TVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFY 241 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 AS+ + Y TG S+ VTGG M Sbjct: 242 ASDKAAYCTGQSINVTGGQVM 262 >3U5T-A nrPDB Length = 267 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 92/251 (36%), Positives = 130/251 (51%), Gaps = 15/251 (5%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +A+VTGA GIG A++ RLA +G TV +AAA E V K G Sbjct: 29 VAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEV------AGKIEAAGGKALTA 82 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 QADVS+ A R L + F V+V+ AGI + + +D+VIAVNLKGTF Sbjct: 83 QADVSDPAAVRRLFATAEEAFG-GVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTF 141 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTN--YAASKAGVIGLTQTAARELGRH 190 + AAQ L G IIN+S+ +VG + + YAA+KAGV +T ++EL Sbjct: 142 NTLREAAQRLR---VGGRIINMST--SQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGR 196 Query: 191 GIRCNSVLPGFIATPM-TQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249 I N+V PG AT + + +V D+ ++ P+ LG P+D+A VAFLA D ++ Sbjct: 197 DITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVN 256 Query: 250 GTSVEVTGGLF 260 G + GG+ Sbjct: 257 GQVLRANGGII 267 >1E3W-A nrPDB Length = 261 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 82/265 (30%), Positives = 131/265 (49%), Gaps = 25/265 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 ++ +A++TG SG+G + + RL G+GAT D+ + + + LGG N Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----------N 57 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE------DDWDK 122 A+V+ + + L + F R V V+CAGI H + +D+ + Sbjct: 58 CIFAPANVTSEKEVQAALTLAKEKFGRI-DVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 Query: 123 VIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGVI 177 VI VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G++ Sbjct: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVADV 236 G+T AR+L GIR ++ PG ATP+ +P V + + +P LGDP + A + Sbjct: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHL 236 Query: 237 VAFLASEDSGYITGTSVEVTGGLFM 261 V + ++ ++ G + + G + M Sbjct: 237 VQMVI--ENPFLNGEVIRLDGAIRM 259 >4IS3-A nrPDB Length = 268 Score = 114 bits (285), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 129/259 (49%), Gaps = 17/259 (6%) Query: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAAC-----DLDRAAAQETVRLLGGP 58 Q N ++ + ++TG GIG A + GA V+ ++D A AQ Sbjct: 18 QGMNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQ--------- 68 Query: 59 GSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSED 118 KE P F D++ A + QV + R V+++ AGIT + +SE+ Sbjct: 69 -LKELYPEEEVLGFAPDLTSRDAVMAAVGQVAQKYGRL-DVMINNAGITSNNVFSRVSEE 126 Query: 119 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 ++ ++ +N+ G F A Q + + +G IIN +S+ G G++ Y ASKA VIG Sbjct: 127 EFKHIMDINVTGVFNGAWCAYQCM-KDAKKGVIINTASVTGIFGSLSGVGYPASKASVIG 185 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVA 238 LT RE+ R IR V PG + T MT P ++++ + +PM + +PE++A+V Sbjct: 186 LTHGLGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPMKRMLEPEEIANVYL 245 Query: 239 FLASEDSGYITGTSVEVTG 257 FLAS+ + IT T+V V G Sbjct: 246 FLASDLASGITATTVSVDG 264 >4DBZ-A nrPDB Length = 281 Score = 114 bits (284), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 88/266 (33%), Positives = 129/266 (48%), Gaps = 30/266 (11%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +ALVTGA SGIG ++ RL EG V C + T++ L A Sbjct: 26 SEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKEL------------REA 73 Query: 71 AFQAD--VSEARAARCLLEQVQACFSR--PPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 +AD + R+ + V A R P V+V+ AG ++++ W V+ Sbjct: 74 GVEADGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVET 133 Query: 127 NLKGTFLVTQAAAQA--LVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 NL G F VT+ +A ++ G G I+NI+S GK G V Y+ASK GV+G T+ Sbjct: 134 NLTGVFRVTKQVLKAGGMLERGT-GRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALG 192 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKV-----------PQKVVDKITEMIPMGHLGDPEDV 233 EL R GI N+V PGF+ TPM V ++ D+IT +P+G P +V Sbjct: 193 LELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEV 252 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGL 259 A++VA+L + +T ++ V GGL Sbjct: 253 AEMVAYLIGPGAAAVTAQALNVCGGL 278 >1NFF-A nrPDB Length = 260 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 125/255 (49%), Gaps = 19/255 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + RL +ALV+G G+G + + EGA V D+ L G Sbjct: 1 MSGRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDI-----------LDEEGKAMAA 49 Query: 65 PRGNHAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 + A + DV++ + ++ F V+V+ AGI + + +W ++ Sbjct: 50 ELADAARYVHLDVTQPAQWKAAVDTAVTAFG-GLHVLVNNAGILNIGTIEDYALTEWQRI 108 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 + VNL G FL +A + + G RGSIINISSI G G V Y A+K V GLT++ Sbjct: 109 LDVNLTGVFLGIRAVVKPMKEAG-RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKST 167 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 A ELG GIR NS+ PG + TPMT VP+ + +G +P +V+++V +LAS+ Sbjct: 168 ALELGPSGIRVNSIHPGLVKTPMTDWVPEDIFQT-----ALGRAAEPVEVSNLVVYLASD 222 Query: 244 DSGYITGTSVEVTGG 258 +S Y TG V GG Sbjct: 223 ESSYSTGAEFVVDGG 237 >2EW8-A nrPDB Length = 249 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 82/260 (31%), Positives = 130/260 (50%), Gaps = 19/260 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRA-AAQETVRLLGGPGSKEG 63 + RL+ LA++TG +GIGRA++ R A EGA +A DL A A+ +R LG Sbjct: 1 MTQRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLG------- 53 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 + DVS+ +QV + F R ++V+ AGI ++ + W K Sbjct: 54 ---RRVLTVKCDVSQPGDVEAFGKQVISTFGR-CDILVNNAGIYPLIPFDELTFEQWKKT 109 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 +N+ FL+ +A + NG G IIN++S + T+Y ++KA IG T+ Sbjct: 110 FEINVDSGFLMAKAFVPGMKRNGW-GRIINLTSTTYWLKIEAYTHYISTKAANIGFTRAL 168 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQ----KVPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 A +LG+ GI N++ P + T T+ V+ + + IP L P D+ AF Sbjct: 169 ASDLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAF 226 Query: 240 LASEDSGYITGTSVEVTGGL 259 LAS+D+ +ITG ++ V GG+ Sbjct: 227 LASDDASFITGQTLAVDGGM 246 >1X1T-A nrPDB Length = 260 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 83/262 (31%), Positives = 127/262 (48%), Gaps = 19/262 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +A+VTG+ SGIG ++ LA +GA + AA E VR G ++ G Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVR--AGLAAQHGVKVLY 59 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A D+S+ A R L++ R ++V+ AGI + + WD ++A+NL Sbjct: 60 DGA---DLSKGEAVRGLVDNAVRQMGRI-DILVNNAGIQHTALIEDFPTEKWDAILALNL 115 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F T AA + G G IINI+S G V + ++ Y A+K GV+G T+ A E Sbjct: 116 SAVFHGTAAALPHMKKQGF-GRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETA 174 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDK------------ITEMIPMGHLGDPEDVADV 236 GI N++ PG++ TP+ +K + +K ++E P PE + Sbjct: 175 GQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGT 234 Query: 237 VAFLASEDSGYITGTSVEVTGG 258 FLAS+ + ITGT+V V GG Sbjct: 235 AVFLASDAAAQITGTTVSVDGG 256 >3A28-C nrPDB Length = 258 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 87/267 (32%), Positives = 135/267 (50%), Gaps = 27/267 (10%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQ--ETVRLLGGPGSKE---GPP 65 S +A+VTG GIGR +S +LA +G +A DL + Q ET++L+ K G Sbjct: 2 SKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLD 61 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + A F + + EA + V+V+ AGI Q + LL ++E+D ++ + Sbjct: 62 VTDKANFDSAIDEAAEKLGGFD-----------VLVNNAGIAQIKPLLEVTEEDLKQIYS 110 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VN+ F QAA++ G +G IIN +SI G + Y+ +K V GLTQ AA+ Sbjct: 111 VNVFSVFFGIQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQ 170 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKV-----------VDKITEMIPMGHLGDPEDVA 234 EL G N+ PG + T M +++ ++ + + I +G PEDVA Sbjct: 171 ELAPKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVA 230 Query: 235 DVVAFLASEDSGYITGTSVEVTGGLFM 261 +V+FLASE+S Y+TG + V GG+ Sbjct: 231 GLVSFLASENSNYVTGQVMLVDGGMLY 257 >4E6P-A nrPDB Length = 259 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 84/278 (30%), Positives = 132/278 (47%), Gaps = 42/278 (15%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD----RAAAQETVRLLGGPGS 60 + RL AL+TG+ GIGRA + EGATVA D+D R AA E GP + Sbjct: 2 MMKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEI-----GPAA 56 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPS------VVVSCAGITQDEFLLH 114 A Q DV+ + + A + ++V+ A + ++ Sbjct: 57 Y---------AVQMDVTRQ-------DSIDAAIAATVEHAGGLDILVNNAALFDLAPIVE 100 Query: 115 MSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKA 174 ++ + ++K+ A+N+ GT QAAA+ +++ G G IIN++S G+ G Y A+KA Sbjct: 101 ITRESYEKLFAINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKA 160 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV----------PQKVVDKIT-EMIP 223 VI LTQ+A +L +H I N++ PG + V P+ ++ E +P Sbjct: 161 AVISLTQSAGLDLIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVP 220 Query: 224 MGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 G +G ED+ + FLAS +S YI + V GG +M Sbjct: 221 FGRMGTAEDLTGMAIFLASAESDYIVSQTYNVDGGNWM 258 >4MOW-A nrPDB Length = 256 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 84/257 (32%), Positives = 131/257 (50%), Gaps = 15/257 (5%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAA-CDLDRAAAQETVRLLGGPGSKEGPP 65 ++L +A+VTGA GIG A++ LA EGA V +A A V + G Sbjct: 10 SKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAG------ 63 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 G A DVS+A A+ +++ + R V+V+ +G+ + + ++E+ + + Sbjct: 64 -GRAVAVGGDVSKAADAQRIVDTAIETYGRL-DVLVNNSGVYEFAPIEAITEEHYRRQFD 121 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 N+ G L TQAA + L G SIINISS+V + Y+ +K V +T A Sbjct: 122 TNVFGVLLTTQAAVKHL---GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLAL 178 Query: 186 ELGRHGIRCNSVLPGFIATPMTQK---VPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 ELG IR N++ PG I T T + + ++ P+G LG+P D+A V FLAS Sbjct: 179 ELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLAS 238 Query: 243 EDSGYITGTSVEVTGGL 259 +D+ ++TG + V+GGL Sbjct: 239 DDARWMTGEHLVVSGGL 255 >3V8B-A nrPDB Length = 283 Score = 107 bits (266), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 93/262 (35%), Positives = 132/262 (50%), Gaps = 25/262 (9%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +AL+TGAGSGIGRA ++ LA +G TV A R +E + G G G Sbjct: 28 SPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAG-------GQAI 80 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLL-HMSEDDWDKVIAVNLK 129 A +ADVS+ R + + F +VV+ AGI + + +WD+ IAVNL+ Sbjct: 81 ALEADVSDELQMRNAVRDLVLKFGH-LDIVVANAGINGVWAPIDDLKPFEWDETIAVNLR 139 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG--KVGNVGQTNYAASKAGVIGLTQTAAREL 187 GTFL L G G+I+ +SSI G G T Y A+KA + + Q A EL Sbjct: 140 GTFLTLHLTVPYLKQRGG-GAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALEL 198 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-----------GHLGDPEDVADV 236 G+H IR N+V PG I T ++ K+ + IP+ G G EDVA++ Sbjct: 199 GKHHIRVNAVCPGAIETNISDNT--KLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAEL 256 Query: 237 VAFLASEDSGYITGTSVEVTGG 258 + FL SE + ++TG+ V + GG Sbjct: 257 IRFLVSERARHVTGSPVWIDGG 278 >5U9P-A nrPDB Length = 265 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 122/254 (48%), Gaps = 11/254 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL AL+TG+G GIG ++ LA GA + D + A R G Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFA-----A 71 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 +HA F DV+E R +++ +A ++V+ AGI + L DDW ++ VN Sbjct: 72 DHAVF--DVAEHAQVRAAIDEFEARVG-AIDILVNNAGIQRRAPLDAFEPDDWHALMRVN 128 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L G F V QA A+ +++ G G IINI S+ ++ YAA+K V LT+ + Sbjct: 129 LDGVFNVAQAVARHMIARG-HGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADW 187 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDS 245 R+GI+ N + PG+ T + + + D + + P G G +++ FLAS S Sbjct: 188 ARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAAS 247 Query: 246 GYITGTSVEVTGGL 259 ++ G ++ V GGL Sbjct: 248 DFVNGQTLFVDGGL 261 >3PPI-A nrPDB Length = 281 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 85/264 (32%), Positives = 129/264 (48%), Gaps = 28/264 (10%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + A A+V+G G+G A RL +G V DL AA++ G Sbjct: 26 KQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADL---AAEK--------GKALADEL 74 Query: 67 GNHAAFQADVSEARAARCLLEQVQAC--FSRPPSVVVSCAGITQDEFLLHMSEDDWD--- 121 GN A F + + + +L ++A R VV+ G + ++ D Sbjct: 75 GNRAEFVS--TNVTSEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGG 132 Query: 122 --KVIAVNLKGTFLVTQAAAQALVS-----NGCRGSIINISSIVGKVGNVGQTNYAASKA 174 K I + L GT+ V + A ++ + NG RG+++ +SI G G +GQT YAA+KA Sbjct: 133 FTKTIDLYLNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKA 192 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDV 233 GVIGLT AAR+L GIR N++ PG + TP+ + V ++ + K IP LG P++ Sbjct: 193 GVIGLTIAAARDLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEF 252 Query: 234 ADVVAFLASEDSGYITGTSVEVTG 257 AD AFL + +GYI G + + G Sbjct: 253 ADAAAFLLT--NGYINGEVMRLDG 274 >3UF0-A nrPDB Length = 273 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 80/249 (32%), Positives = 126/249 (50%), Gaps = 13/249 (5%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 A+VTGAGSGIGRA++ A GA V A + + G GS E A Sbjct: 34 AVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAE--------AVV 85 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 AD+++ A + E++ A +R V+V+ AGI +S W +V+ VNL ++ Sbjct: 86 ADLADLEGAANVAEELAA--TRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWV 143 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 ++++ A++++G G I+ I+S++ G YAASK V+GLT+ A E G+ Sbjct: 144 LSRSFGTAMLAHGS-GRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVG 202 Query: 194 CNSVLPGFIATPMTQ--KVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 N++ PG++ T T + + +IT IP G PED+ FLAS+ + Y+ G Sbjct: 203 VNALAPGYVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDAASYVHGQ 262 Query: 252 SVEVTGGLF 260 + V GG Sbjct: 263 VLAVDGGWL 271 >3T7C-A nrPDB Length = 299 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 83/282 (29%), Positives = 130/282 (46%), Gaps = 36/282 (12%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAA------------AQETVRLL 55 ++ +A +TGA G GR+ ++ LA EGA + A D+ + ETVR + Sbjct: 25 KVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQV 84 Query: 56 GGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHM 115 G + A Q DV + A + ++ R V+ + A ++ L M Sbjct: 85 EALGRR-------IIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRM 137 Query: 116 SEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAG 175 W +I VNL G ++ + A +++ GSI+ SSI G G NY ASK G Sbjct: 138 DPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHG 197 Query: 176 VIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ----------------KVVDKIT 219 + GL +T A ELG IR N V P +ATPM P +V + Sbjct: 198 LHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQM 257 Query: 220 EMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 ++P+ ++ +P D+++ + FL S+D+ YITG S+ V GG + Sbjct: 258 HVLPIPYV-EPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >3W8F-A nrPDB Length = 260 Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 84/264 (31%), Positives = 126/264 (47%), Gaps = 21/264 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ A+VTG+ SGIG A++ LA GA V + E R S G Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERER------STLESKFGV 55 Query: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A + AD+S+A+A R + + ++V+ AGI + D W+ +IA+N Sbjct: 56 KAYYLNADLSDAQATRDFIAKAAEALG-GLDILVNNAGIQHTAPIEEFPVDKWNAIIALN 114 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L F T AA + G G IINI+S G V +V ++ Y A+K GV+GLT+ A E Sbjct: 115 LSAVFHGTAAALPIMQKQGW-GRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALEN 173 Query: 188 GRHGIRCNSVLPGFIATPMTQK-----VPQKVVD-------KITEMIPMGHLGDPEDVAD 235 GI CN++ PG++ TP+ +K QK +D + E P PE + Sbjct: 174 AGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGG 233 Query: 236 VVAFLASEDSGYITGTSVEVTGGL 259 FL+S + +TGT++ + GG Sbjct: 234 AAVFLSSAAADQMTGTTLSLDGGW 257 >2Q2Q-A nrPDB Length = 255 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 81/264 (30%), Positives = 123/264 (46%), Gaps = 24/264 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPRG 67 L+ ALVTG+ SGIG ++ LA GA + D A A + ++ G Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEI-------ARHGVKAV 54 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 +H A +DV++ A L E+ ++V+ AGI + + WDK+IA+N Sbjct: 55 HHPADLSDVAQIEALFALAEREFGGVD----ILVNNAGIQHVAPVEQFPLESWDKIIALN 110 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L F T+ A + + G IINI+S+ G VG+ G+ Y A+K GV+GLT+ E Sbjct: 111 LSAVFHGTRLALPGMRARNW-GRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLET 169 Query: 188 GRHGIRCNSVLPGFIATPMTQK-----------VPQKVVDKITEMIPMGHLGDPEDVADV 236 + CN++ PG++ TP+ QK Q D + E P PE + ++ Sbjct: 170 ATSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGEL 229 Query: 237 VAFLASEDSGYITGTSVEVTGGLF 260 V FL SE + G + V GG Sbjct: 230 VLFLCSEAGSQVRGAAWNVDGGWL 253 >5OJG-A nrPDB Length = 260 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 125/259 (48%), Gaps = 16/259 (6%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 R +A+VT A GIG A++ RL EGA+V ++ E + L G + Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDE-FLLHMSEDDWDKVIAV 126 H A D + L++ F + +++V+ GI +L +S+ WDK+ V Sbjct: 67 GHIASTDD------QKKLVDFTLQKFGKI-NILVNNHGINPAFGHILEVSDQVWDKLFEV 119 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 N+K F +T+ + G G+II +S G Y +K ++GLT+ A Sbjct: 120 NVKAGFQMTKLVHPHIAKEGG-GAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMG 178 Query: 187 LGRHGIRCNSVLPGFIATPMTQKV------PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 L + IR N + PG I T M+Q + +K + I E I +G LG P+D A VA+L Sbjct: 179 LAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQE-IALGRLGVPDDCAGTVAYL 237 Query: 241 ASEDSGYITGTSVEVTGGL 259 AS+DS YITG + + GG+ Sbjct: 238 ASDDSSYITGEMIIIAGGV 256 >2ZAT-A nrPDB Length = 260 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 87/258 (33%), Positives = 128/258 (49%), Gaps = 22/258 (8%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGPPRG 67 L + +ALVT + GIG A++ RLA +GA V + TV L G G S G Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTV-- 69 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF---LLHMSEDDWDKVI 124 H D R L + ++VS A + + F ++ +E+ WDK++ Sbjct: 70 CHVGKAED-------RERLVAMAVNLHGGVDILVSNAAV--NPFFGNIIDATEEVWDKIL 120 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSI--VGKVGNVGQTNYAASKAGVIGLTQT 182 VN+K T L+T+A + G GS++ +SS+ N+G Y SK ++GLT+ Sbjct: 121 HVNVKATVLMTKAVVPEMEKRGG-GSVLIVSSVGAYHPFPNLGP--YNVSKTALLGLTKN 177 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDK--ITEMIPMGHLGDPEDVADVVAFL 240 A EL IR N + PG I T +Q + K + E + + LG+PED A +V+FL Sbjct: 178 LAVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFL 237 Query: 241 ASEDSGYITGTSVEVTGG 258 SED+ YITG +V V GG Sbjct: 238 CSEDASYITGETVVVGGG 255 >4DA9-A nrPDB Length = 280 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 65/194 (33%), Positives = 108/194 (55%), Gaps = 8/194 (4%) Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVV--VSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 +AD+++ + + ++ V A F R +V A I +D+FL + +++D ++ VNL+ Sbjct: 84 LRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFL-DLKPENFDTIVGVNLR 142 Query: 130 GTFLVTQAAAQALVSNGCRGS--IINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 GT TQA +A++++ R S IINI+S+ + + + +Y SKAG+ +Q A L Sbjct: 143 GTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRL 202 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE--MIPMGHLGDPEDVADVVAFLASEDS 245 GI V PG I + MT V K D + E ++PM G+PED+ ++VA LA Sbjct: 203 AETGIAVFEVRPGIIRSDMTAAVSGKY-DGLIESGLVPMRRWGEPEDIGNIVAGLAGGQF 261 Query: 246 GYITGTSVEVTGGL 259 G+ TG+ ++ GGL Sbjct: 262 GFATGSVIQADGGL 275 >3O4R-A nrPDB Length = 261 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 83/259 (32%), Positives = 131/259 (50%), Gaps = 18/259 (6%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG-SKEGP 64 ++ L + +ALVT + GIG A++ RLA +GA V + + V L G G S G Sbjct: 10 RDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGT 69 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF---LLHMSEDDWD 121 H D R L ++VS A + + F ++ ++E+ WD Sbjct: 70 V--CHVGKAED-------RERLVATAVKLHGGIDILVSNAAV--NPFFGSIMDVTEEVWD 118 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 K + +N+K L+T+A + G GS++ +SSI + G + Y SK ++GLT+ Sbjct: 119 KTLDINVKAPALMTKAVVPEMEKRGG-GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTK 177 Query: 182 TAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAF 239 T A EL IR N + PG I T ++ + ++ + + E + + LG+PED A +V+F Sbjct: 178 TLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSF 237 Query: 240 LASEDSGYITGTSVEVTGG 258 L SED+ YITG +V V GG Sbjct: 238 LCSEDASYITGETVVVGGG 256 >1AE1-A nrPDB Length = 273 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 73/257 (28%), Positives = 118/257 (45%), Gaps = 14/257 (5%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ ALVTG GIG A+ LAG GA V C + E + + G N Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGL-------N 71 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 D+ L++ V F +++V+ AG+ + +E D++ ++ N Sbjct: 72 VEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNF 131 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 + + ++Q A L+ G++I +SSI G + Y+ASK + +T++ A E Sbjct: 132 EAAYHLSQIA-YPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWA 190 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQK------VVDKITEMIPMGHLGDPEDVADVVAFLAS 242 + IR NSV PG I TP+ + +K +D PMG G P++V+ ++AFL Sbjct: 191 KDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCF 250 Query: 243 EDSGYITGTSVEVTGGL 259 + YITG + GG Sbjct: 251 PAASYITGQIIWADGGF 267 >5EJ2-A nrPDB Length = 308 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 82/279 (29%), Positives = 130/279 (46%), Gaps = 24/279 (8%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-----DRAAAQETVRLLGGPG 59 + R+ +A ++GA G GR+ +VRLA EGA + A D+ + A T L Sbjct: 31 MTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETA 90 Query: 60 SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD 119 Q DV + A + ++ R ++V+ AG+ D LH D+ Sbjct: 91 DLVKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRL-DIIVANAGVGTDGRKLHKIRDN 149 Query: 120 -WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 W +I +NL G + +A ++S G GSI+ SS+ G+ +Y A+K GVIG Sbjct: 150 VWQDMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIG 209 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKV--------------PQKV--VDKITEMI 222 L + A ELG H IR N+VLP ++T M P + ++ + Sbjct: 210 LMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTL 269 Query: 223 PMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 P+ + D D+++ V FLAS++S Y+TG S+ V G + Sbjct: 270 PVPWV-DASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >3UVE-A nrPDB Length = 286 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 82/279 (29%), Positives = 127/279 (45%), Gaps = 26/279 (9%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL---------DRAAAQETVRLL 55 + R+ +A VTGA G GR+ +VRLA EGA + A D+ D A T L Sbjct: 5 MTGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDL 64 Query: 56 GGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD-EFLLH 114 + DV + A + ++ R ++V+ AGI + L Sbjct: 65 AETADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRL-DIIVANAGIGNGGDTLDK 123 Query: 115 MSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKA 174 SE+DW ++I +NL G + +A +++ G GSII SS+ G +Y A+K Sbjct: 124 TSEEDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKH 183 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK----------VPQKVVDKITEMIPM 224 GV+GL + ELG+H IR NSV P + TPM + D + + M Sbjct: 184 GVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQM 243 Query: 225 GH-----LGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 H +P D+++ V F AS+++ YITG ++ + G Sbjct: 244 FHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAG 282 >3V2H-A nrPDB Length = 281 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 80/262 (30%), Positives = 133/262 (50%), Gaps = 19/262 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 + + A++TG+ SGIG A++ LA GA + L+ A + +R + G G Sbjct: 23 MMTKTAVITGSTSGIGLAIARTLAKAGANIV---LNGFGAPDEIRTV--TDEVAGLSSGT 77 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 AD+++ ++ V F ++V+ AG+ E + + WD++IAVNL Sbjct: 78 VLHHPADMTKPSEIADMMAMVADRFGGA-DILVNNAGVQFVEKIEDFPVEQWDRIIAVNL 136 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 +F + A + G G IINI+S G V + ++ Y A+K G++GLT+T A E+ Sbjct: 137 SSSFHTIRGAIPPMKKKGW-GRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVA 195 Query: 189 RHGIRCNSVLPGFIATPMTQK-VPQKVVDK-ITEMIPMGHL---GDP-------EDVADV 236 G+ NS+ PG++ TP+ +K +P + + ITE + + G P E VA + Sbjct: 196 ESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASL 255 Query: 237 VAFLASEDSGYITGTSVEVTGG 258 +LA +D+ ITGT V + GG Sbjct: 256 ALYLAGDDAAQITGTHVSMDGG 277 >2HSD-A nrPDB Length = 253 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 64/160 (40%), Positives = 90/160 (56%), Gaps = 1/160 (0%) Query: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159 +V+ AGI+ FL S + + KV+ +NL G F+ + A+ G GSI+NISS G Sbjct: 83 LVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGG-GSIVNISSAAG 141 Query: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219 +G ++Y ASK GV GL++ AA ELG IR NSV PG TPMT + + + Sbjct: 142 LMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNY 201 Query: 220 EMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 PMG +G+P ++A V L S+ S Y+TG + V GG Sbjct: 202 PNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGAELAVDGGW 241 >3V2G-A nrPDB Length = 271 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 88/248 (35%), Positives = 128/248 (51%), Gaps = 16/248 (6%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAA-AQETVRLLGGPGSKEGPPRGNHAAF 72 A VTG GIG A++ RLA EGA VA ++ A AQ V + G G A Sbjct: 34 AFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAG-------GRAVAI 86 Query: 73 QADVSEARA-ARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 +AD +A A + + E V+A ++V+ AGI L + D+D+V+AVN + Sbjct: 87 RADNRDAEAIEQAIRETVEALGGL--DILVNSAGIWHSAPLEETTVADFDEVMAVNFRAP 144 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F+ ++A++ L G G II I S + + V G + Y+ASKA + GLT+ AR+LG Sbjct: 145 FVAIRSASRHL---GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPR 201 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 GI N V PG T M + E I G G+P+D+A +VA+LA ++TG Sbjct: 202 GITVNIVHPGSTDTDM-NPADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQGKFVTG 260 Query: 251 TSVEVTGG 258 S+ + GG Sbjct: 261 ASLTIDGG 268 >4TRR-A nrPDB Length = 269 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 78/267 (29%), Positives = 134/267 (50%), Gaps = 20/267 (7%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + L A+VTGA SGIG+ +++ LA GA VA DL++ A + G K Sbjct: 10 SNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKA---- 65 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 DV+ A +++V F ++VS AGI + + S DW K+ A+ Sbjct: 66 ---IGVAMDVTNEEAVNTGIDKVAEAFG-SVDILVSNAGIQIVNPIENYSFADWKKMQAI 121 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 ++ G FL T+AA + + + G +I + S+ + ++ Y +K G++GL + A+E Sbjct: 122 HVDGAFLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKE 181 Query: 187 LGRHGIRCNSVLPGFIATPMTQK-VPQKVV------DKITEMIPMGHLGD-----PEDVA 234 +H +R + V PGF+ TP+ K +P++ +++ + + +G+ D +DVA Sbjct: 182 GAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVA 241 Query: 235 DVVAFLASEDSGYITGTSVEVTGGLFM 261 V FL++ S +TG S V+ G FM Sbjct: 242 QTVLFLSAFPSAALTGQSFIVSHGWFM 268 >3OML-A nrPDB Length = 613 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 87/258 (33%), Positives = 125/258 (48%), Gaps = 43/258 (16%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL----------DRAA--AQETVRLL 55 R +A+VTGAG+G+GR ++ A GA V DL RAA + +R Sbjct: 16 RYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 56 GGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHM 115 GG AD + ++E F R ++V+ AGI +D L+ Sbjct: 76 GGEAV-------------ADYNSVIDGAKVIETAIKAFGRV-DILVNNAGILRDRSLVKT 121 Query: 116 SEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAG 175 SE DW+ V V+LKG+F TQAA + G II SS G GN GQ NY A+K G Sbjct: 122 SEQDWNLVNDVHLKGSFKCTQAAFPYMKKQNY-GRIIMTSSNSGIYGNFGQVNYTAAKMG 180 Query: 176 VIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVA 234 +IGL T A E R+ + CN ++P A+ MT+ + P + +++ P+ +A Sbjct: 181 LIGLANTVAIEGARNNVLCNVIVPT-AASRMTEGILPDILFNELK----------PKLIA 229 Query: 235 DVVAFL---ASEDSG-YI 248 VVA+L + ED+G YI Sbjct: 230 PVVAYLCHESCEDNGSYI 247 >3D3W-A nrPDB Length = 244 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 76/249 (30%), Positives = 117/249 (46%), Gaps = 20/249 (8%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTGAG GIGR L GA V A +A VR PG + Sbjct: 11 LVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVR--ECPGIEP---------VCV 59 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 D+ + A L V P ++V+ A + + L ++++ +D+ VNL+ V Sbjct: 60 DLGDWEATERALGSVG-----PVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 114 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 +Q A+ L++ G G+I+N+SS + + Y ++K + LT+ A ELG H IR Sbjct: 115 SQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRV 174 Query: 195 NSVLPGFIATPMTQKV---PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 N+V P + T M Q P K + IP+G + E V + + FL S+ SG TG+ Sbjct: 175 NAVNPTVVMTSMGQATWSDPHK-AKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGS 233 Query: 252 SVEVTGGLF 260 ++ V GG + Sbjct: 234 TLPVEGGFW 242 >2AG5-A nrPDB Length = 246 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 129/258 (50%), Gaps = 25/258 (9%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL + ++T A GIG+A ++ A EGA V A D++ + QE L PG + Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE---LEKYPGIQTRV--- 56 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 DV++ + +V+ V+ + AG +L E DWD + +N Sbjct: 57 ------LDVTKKKQIDQFANEVERL-----DVLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-GNVGQTNYAASKAGVIGLTQTAARE 186 ++ +L+ +A +++ G+IIN+SS+ V G V + Y+ +KA VIGLT++ A + Sbjct: 106 VRSMYLMIKAFLPKMLAQK-SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD 164 Query: 187 LGRHGIRCNSVLPGFIATPMTQKV------PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 + GIRCN V PG + TP Q+ P++ + + G E++A + +L Sbjct: 165 FIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 Query: 241 ASEDSGYITGTSVEVTGG 258 AS++S Y+TG V + GG Sbjct: 225 ASDESAYVTGNPVIIDGG 242 >1CYD-A nrPDB Length = 244 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 77/249 (30%), Positives = 120/249 (48%), Gaps = 18/249 (7%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 ALVTGAG GIGR L GA V A + + V L +KE P Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVVAVTRTNS---DLVSL-----AKECP---GIEPVC 58 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 D+ + A L + P ++V+ A + + L ++++ +D+ +VNL+ F Sbjct: 59 VDLGDWDATEKALGGIG-----PVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQ 113 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 V+Q A+ +++ G GSI+N+SS+V V Y+++K + LT+ A ELG H IR Sbjct: 114 VSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIR 173 Query: 194 CNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 NSV P + T M +KV + K+ E P+ + EDV + + FL S+ S +G Sbjct: 174 VNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGG 233 Query: 252 SVEVTGGLF 260 + V G Sbjct: 234 GILVDAGYL 242 >4AVY-A nrPDB Length = 242 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 117/250 (46%), Gaps = 28/250 (11%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG SGIG A++++ A GA V A LD G HA Sbjct: 15 LVTGGSSGIGAAIAMQFAELGAEVVALGLD--------------------ADGVHAPRHP 54 Query: 75 DVSEARAARCLLEQVQACFSRPP--SVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 + +++Q F P V+V+ AGI++D ++ +++V+ +NL Sbjct: 55 RIRREELDITDSQRLQRLFEALPRLDVLVNNAGISRDREEYDLAT--FERVLRLNLSAAM 112 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 L +Q A L G GSI+NI+S+ G+ + Y+ASK ++ LT++ A E I Sbjct: 113 LASQLARPLLAQRG--GSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERI 170 Query: 193 RCNSVLPGFIATPMTQ--KVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 R N++ PG+I TP+ K + +I + P+ G+ +VA AFL + ++TG Sbjct: 171 RVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTG 230 Query: 251 TSVEVTGGLF 260 + V GG Sbjct: 231 AVLAVDGGYL 240 >4EGF-A nrPDB Length = 266 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 59/166 (35%), Positives = 88/166 (53%), Gaps = 2/166 (1%) Query: 98 SVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSI 157 V+V+ AGI+ + ++ +D IAVNL+ L+ A +A+V+ G G+II ++S Sbjct: 100 DVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLASAVGKAMVAAGEGGAIITVASA 159 Query: 158 VGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVV 215 Y SKAG++ T+ ARELG HGIR NSV P + T M Q+V + Sbjct: 160 AALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVCPTVVLTEMGQRVWGDEAKS 219 Query: 216 DKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 + IP+G P +V+D V +LAS+ + I G + V GG M Sbjct: 220 APMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVDIPVDGGYTM 265 >5YSS-A nrPDB Length = 256 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 76/264 (28%), Positives = 127/264 (48%), Gaps = 24/264 (9%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPR 66 L ALVTG+ SGIG ++ LA GAT+ D AA++ V ++ G Sbjct: 2 NLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAV-------AQYGKTP 54 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 G H A D+S+ ++ ++ F ++++ AGI + D W+ +IA+ Sbjct: 55 GYHGA---DLSDEAQIADMMRYAESEFGGV-DILINNAGIQHVSPIETFPVDKWNAIIAI 110 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 NL F T+ A + + G IINI+S+ G V + ++ Y A+K GV+GLT+T A E Sbjct: 111 NLSSVFHTTRLALPGMRARNW-GRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALE 169 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDK-----------ITEMIPMGHLGDPEDVAD 235 + I CN++ PG++ TP+ Q+ K + + + E P PE + + Sbjct: 170 TAQTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGN 229 Query: 236 VVAFLASEDSGYITGTSVEVTGGL 259 + FL S+ + + G + + GG Sbjct: 230 LALFLCSDGAAQVRGVAWNMDGGW 253 >3GDF-A nrPDB Length = 267 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 79/259 (30%), Positives = 124/259 (47%), Gaps = 14/259 (5%) Query: 6 QNRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRA-AAQETVRLLGGPGSKE 62 Q L+ + +VTGA G+G + A GA VA RA A+E V+ L E Sbjct: 15 QLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKEL------E 68 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 A++ V + L++ V A F + + + + AG T D +L S + W+ Sbjct: 69 KTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIAN-AGATADSGILDGSVEAWNH 127 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNV--GQTNYAASKAGVIGLT 180 V+ V+L GTF +A G GS++ +S+ G + N QT+Y +KAG I + Sbjct: 128 VVQVDLNGTFHCAKAVGHHFKERGT-GSLVITASMSGHIANFPQEQTSYNVAKAGCIHMA 186 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 ++ A E R R NS+ PG+I T ++ VP++ MIPMG G +++ + Sbjct: 187 RSLANEW-RDFARVNSISPGYIDTGLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYF 245 Query: 241 ASEDSGYITGTSVEVTGGL 259 AS+ S Y TG + + GG Sbjct: 246 ASDASTYTTGADLLIDGGY 264 >1HXH-A nrPDB Length = 253 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 83/256 (32%), Positives = 126/256 (49%), Gaps = 22/256 (8%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 NRL+ +ALVTG SG+G V L GEGA VA D++ AA Q+ L Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAEL----------- 50 Query: 67 GNHAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 G + F + DVS ++ VQ +V+V+ AGI + +D+ +++ Sbjct: 51 GERSMFVRHDVSSEADWTLVMAAVQRRLG-TLNVLVNNAGILLPGDMETGRLEDFSRLLK 109 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 +N + F+ Q A+ G GSIIN++S+ + Y+ASKA V LT+ AA Sbjct: 110 INTESVFIGCQQGIAAMKETG--GSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAAL 167 Query: 186 ELGRHG--IRCNSVLPGFIATPMTQ-KVPQKVVDKITEMIPM----GHLGDPEDVADVVA 238 + G IR NS+ P I TPM Q +P+ V ++ P G PE +A +V Sbjct: 168 SCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVL 227 Query: 239 FLASEDSGYITGTSVE 254 FLAS++S ++G+ + Sbjct: 228 FLASDESSVMSGSELH 243 >4CR6-A nrPDB Length = 271 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 53/155 (34%), Positives = 85/155 (54%), Gaps = 7/155 (4%) Query: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS-----NGCRGSIINISSIVGKVGNVGQ 166 L +S+ DWD+ + VN+ GTFL +A A+A+V+ +G II I S+ + Sbjct: 104 FLDLSDADWDRYVDVNMTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEA 163 Query: 167 TNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP--MTQKVPQKVVDKITEMIPM 224 Y A+K GV LT+ A +L RHGI N + PG + T ++ +++ + + + Sbjct: 164 AAYVAAKGGVAMLTRAMAVDLARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVAL 223 Query: 225 GHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 G G PE+VA FLA + S +ITG+++ + GGL Sbjct: 224 GRPGLPEEVATAAVFLAEDGSSFITGSTITIDGGL 258 Score = 31.6 bits (70), Expect = 0.33, Method: Compositional matrix adjust. Identities = 20/41 (48%), Positives = 23/41 (56%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL 43 S+ RL A+VTGA GIGRA EGA+V A DL Sbjct: 7 SRRPGRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDL 47 >3R3S-A nrPDB Length = 294 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 81/260 (31%), Positives = 122/260 (46%), Gaps = 24/260 (9%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL--DRAAAQETVRLLGGPGSKEGPP 65 RL+ ALVTG SGIGRA ++ A EGA VA L + AQ+ L+ G K Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKA--- 102 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 D+S+ AR L+ + + + + T + ++ + + + A Sbjct: 103 ----VLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFA 158 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VN+ F +TQ A L+ G SII SSI + +YAA+KA ++ ++ A+ Sbjct: 159 VNVFALFWITQEAI-PLLPKGA--SIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAK 215 Query: 186 ELGRHGIRCNSVLPGFIATPM------TQ-KVPQKVVDKITEMIPMGHLGDPEDVADVVA 238 ++ GIR N V PG I T + TQ K+PQ + PM G P ++A V Sbjct: 216 QVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQ-----FGQQTPMKRAGQPAELAPVYV 270 Query: 239 FLASEDSGYITGTSVEVTGG 258 +LAS++S Y+T V GG Sbjct: 271 YLASQESSYVTAEVHGVCGG 290 >3UN1-A nrPDB Length = 260 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 61/186 (32%), Positives = 102/186 (54%), Gaps = 9/186 (4%) Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 D+S+ A ++ + F R S+V + AG+ + + M+++D+D + VN+ G F + Sbjct: 76 DISKPETADRIVREGIERFGRIDSLV-NNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHI 134 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAAS--KAGVIGLTQTAARELGRHGI 192 TQ AA ++ G G I++I++ + VG + AS K G+ +T++ A E R G+ Sbjct: 135 TQRAAAEMLKQGS-GHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGV 193 Query: 193 RCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTS 252 R N+V PG I TPM P + + + P+G +G+ DV D V +L E +G+ITG Sbjct: 194 RVNAVSPGVIKTPMH---PAETHSTLAGLHPVGRMGEIRDVVDAVLYL--EHAGFITGEI 248 Query: 253 VEVTGG 258 + V GG Sbjct: 249 LHVDGG 254 >2AE2-A nrPDB Length = 260 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 68/256 (26%), Positives = 121/256 (47%), Gaps = 13/256 (5%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L ALVTG GIG + LA GA+V C ++ + + G K Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKV------ 60 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A D+S + L+ V F +++V+ AGI + + +D+ ++++N Sbjct: 61 -EASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINF 119 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 + + ++ A + RG+++ ISS+ G + + Y A+K + LT+ A E Sbjct: 120 EAAYHLS-VLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWA 178 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQ-----KVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 + IR N V PG IAT + + Q + ++K+ + + +G+P+++A +VAFL Sbjct: 179 KDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFP 238 Query: 244 DSGYITGTSVEVTGGL 259 + Y+TG + V GGL Sbjct: 239 AASYVTGQIIYVDGGL 254 >2GDZ-A nrPDB Length = 267 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 127/258 (49%), Gaps = 32/258 (12%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +ALVTGA GIGRA + L +GA VA D + A + L ++ P+ Sbjct: 9 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL----HEQFEPQKT-LFI 63 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL---- 128 Q DV++ + R +V F R ++V+ AG+ +E +W+K + +NL Sbjct: 64 QCDVADQQQLRDTFRKVVDHFGRL-DILVNNAGVN--------NEKNWEKTLQINLVSVI 114 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR--E 186 GT+L ++ + G G IIN+SS+ G + Q Y ASK G++G T++AA Sbjct: 115 SGTYLGLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 172 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQ--------KVVDKITEMIPMGHLGDPEDVADVVA 238 L G+R N++ PGF+ T + + + + + D I +MI + DP +A+ + Sbjct: 173 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 232 Query: 239 FLASEDSGYITGTSVEVT 256 L +D+ + G +++T Sbjct: 233 TLIEDDA--LNGAIMKIT 248 >1AHH-A nrPDB Length = 255 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 125/252 (49%), Gaps = 11/252 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL A++TGAG+GIG+ +++ A GA+V D++ AA V + G G Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-------G 60 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A + D++ + L + + + +V + G F + M+ D+ + +N Sbjct: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMA--DFRRAYELN 118 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 + F ++Q A + NG G I+ I+S+ + N+ T+YA+SKA L + A +L Sbjct: 119 VFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 Query: 188 GRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 G IR N + PG I T + V ++ K+ + P+ LG P+D+A+ FL S + Sbjct: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 Query: 247 YITGTSVEVTGG 258 +++G + V+GG Sbjct: 238 WVSGQILTVSGG 249 >1YXM-A nrPDB Length = 303 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 85/276 (30%), Positives = 127/276 (46%), Gaps = 30/276 (10%) Query: 1 MASQLQNR-------LRSALALVTGAGSGIGRAVSVRLA--GEGATVAACDLDR--AAAQ 49 MAS + R L+ +A+VTG +GIG+A+ L G +A+ L+R +AA Sbjct: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 Query: 50 ETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD 109 E L P +K+ Q ++ L++ F + +V + G Sbjct: 61 ELQANL--PPTKQA----RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG---- 110 Query: 110 EFLL---HMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQ 166 +FL H+S W V+ NL GTF + +A + + GSI+NI + K G Sbjct: 111 QFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG-GSIVNII-VPTKAGFPLA 168 Query: 167 TNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFI----ATPMTQKVPQKVVDKITEMI 222 + A++AGV LT++ A E GIR N V PG I A Q + + I Sbjct: 169 VHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI 228 Query: 223 PMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 P +G PE+V+ VV FL S + +ITG SV+V GG Sbjct: 229 PAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGG 264 >5IZ4-A nrPDB Length = 271 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 75/261 (28%), Positives = 127/261 (48%), Gaps = 24/261 (9%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLD---RAAAQETVRLLGGPGSKEGPPRGNHAA 71 ++TG+ SGIG A ++R A G +VA + D R AA L G++ Sbjct: 18 VITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQT-------LI 70 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQ---DEFLLHMSEDDWDKVIAVNL 128 F ADV + R ++ V + + R +++ +CAG T+ + + ++++V VNL Sbjct: 71 FDADVGKDADCRHAVDMVASRWQRIDALI-NCAGTTRVIPHNAFDQIDDFEFERVYRVNL 129 Query: 129 KGTFLVTQAAAQALVSNGC---RGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 G + +T+AA L + S++N+SS+ G G YAASK V LT + AR Sbjct: 130 IGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLAR 189 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQK-----VVDKITEMIPMGHLGDPEDVADVVAFL 240 L H IR N++ PG + + +V V+ ++TE P+ + P ++A++ FL Sbjct: 190 NLAPH-IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL 248 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 + + ITG + GL + Sbjct: 249 TAH-APAITGQVIAAENGLLL 268 >2FWM-X nrPDB Length = 250 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 77/257 (29%), Positives = 118/257 (45%), Gaps = 35/257 (13%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 VTGAG GIG A ++ GA V D+A QE P + E Sbjct: 11 WVTGAGKGIGYATALAFVEAGAKVTG--FDQAFTQEQY-----PFATE----------VM 53 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF-L 133 DV++A + +++ A R ++V + AGI + +S++DW + AVN+ G F L Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALV-NAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 112 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 Q Q G G+I+ ++S +G + Y ASKA + L + EL G+R Sbjct: 113 FQQTMNQFRRQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 170 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEM------------IPMGHLGDPEDVADVVAFLA 241 CN V PG T M + + V D E IP+G + P+++A+ + FLA Sbjct: 171 CNVVSPGSTDTDMQRTL--WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 228 Query: 242 SEDSGYITGTSVEVTGG 258 S+ + +IT + V GG Sbjct: 229 SDLASHITLQDIVVDGG 245 >2BGM-A nrPDB Length = 278 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 7/153 (4%) Query: 112 LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTN-YA 170 +L +D+ +V+ +N+ G FLV + AA+ ++ +GSI+ +SI G ++ Y Sbjct: 110 ILEAGNEDFKRVMDINVYGAFLVAKHAARVMIP-AKKGSIVFTASISSFTAGEGVSHVYT 168 Query: 171 ASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-----G 225 A+K V+GLT + ELG +GIR N V P +A+P+ V ++ E+ G Sbjct: 169 ATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGVDSSRVEELAHQAANLKG 228 Query: 226 HLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 L EDVAD VA+LA ++S Y++G ++ + GG Sbjct: 229 TLLRAEDVADAVAYLAGDESKYVSGLNLVIDGG 261 >5JS6-A nrPDB Length = 274 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/231 (28%), Positives = 109/231 (47%), Gaps = 22/231 (9%) Query: 35 GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF-QADVSEARAARCLLEQVQACF 93 GA V CD D + + + L G A F DV++ + L+ + F Sbjct: 35 GARVVICDKDESGGRALEQELPG------------AVFILCDVTQEDDVKTLVSETIRRF 82 Query: 94 SRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIIN 153 R VV + + S + +++ +NL GT+ +T+ A L + +G++IN Sbjct: 83 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKS--QGNVIN 140 Query: 154 ISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV--- 210 ISS+VG +G Y A+K V +T+ A + +G+R N + PG I TP+ +++ Sbjct: 141 ISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAAL 200 Query: 211 ---PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 P+ + + P+G +G P +V FLASE + + TG + VTGG Sbjct: 201 MPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGG 250 >1DOH-A nrPDB Length = 283 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 74/268 (27%), Positives = 124/268 (46%), Gaps = 26/268 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRA-AAQETVRLLGGPGSKEGPPRG 67 L +ALVTGAG GIGR +++ L G V + +A+E V + GS Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGS------- 79 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + A +A+V + E+ F + +V S +G+ + ++ +++D+V +N Sbjct: 80 DAACVKANVGVVEDIVRMFEEAVKIFGKL-DIVCSNSGVVSFGHVKDVTPEEFDRVFTIN 138 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTN-YAASKAGVIGLTQTAARE 186 +G F V + A + L G +I + SI G+ V + Y+ SK + + A + Sbjct: 139 TRGQFFVAREAYKHLEIGG---RLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAID 195 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVV--------DKITEMI-----PMGHLGDPEDV 233 + I N V PG I T M V ++ + +++ E P+ +G P D+ Sbjct: 196 MADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDI 255 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGLFM 261 A VV FLAS D G++TG + + GG M Sbjct: 256 ARVVCFLASNDGGWVTGKVIGIDGGACM 283 >2B4Q-A nrPDB Length = 276 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 118/259 (45%), Gaps = 23/259 (8%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 +ALVTG GIG+ ++ L GA V C D A +T L G + P Sbjct: 31 IALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIP------- 83 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 AD+S AR L + + +R ++V+ AG + L W+KV+ +N+ F Sbjct: 84 -ADLSSEAGARRLAQALGELSAR-LDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVF 141 Query: 133 LVTQAAAQAL-----VSNGCRGSIINISSIVGKVGNVGQTNYA--ASKAGVIGLTQTAAR 185 Q L N R +INI S+ G + +G+ YA SKA + L++ A+ Sbjct: 142 SCIQQLLPLLRRSASAENPAR--VINIGSVAG-ISAMGEQAYAYGPSKAALHQLSRMLAK 198 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKV---PQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 EL I N + PG + MT+ + PQ ++ + IPMG G PE++A + LA Sbjct: 199 ELVGEHINVNVIAPGRFPSRMTRHIANDPQ-ALEADSASIPMGRWGRPEEMAALAISLAG 257 Query: 243 EDSGYITGTSVEVTGGLFM 261 Y+TG + + GG + Sbjct: 258 TAGAYMTGNVIPIDGGFHL 276 >1O5I-A nrPDB Length = 249 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/254 (27%), Positives = 117/254 (46%), Gaps = 29/254 (11%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 +R LV A GIGRAV+ L+ EGA V C A +E ++ R Sbjct: 17 IRDKGVLVLAASRGIGRAVADVLSQEGAEVTIC----ARNEELLK------------RSG 60 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 H D+ + L E+V+ ++V AG + F ++ +D+ + I Sbjct: 61 HRYVVCDLR--KDLDLLFEKVKEV-----DILVLNAGGPKAGFFDELTNEDFKEAIDSLF 113 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISS--IVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 + + A+ G G I+ I+S ++ + N+ +N A + + G +T + E Sbjct: 114 LNMIKIVRNYLPAMKEKGW-GRIVAITSFSVISPIENLYTSNSA--RMALTGFLKTLSFE 170 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE-MIPMGHLGDPEDVADVVAFLASEDS 245 + +GI N V PG+ T +++ + K E IPM + PE++A VVAFL SE + Sbjct: 171 VAPYGITVNCVAPGWTETERVKELLSEEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKA 230 Query: 246 GYITGTSVEVTGGL 259 Y+TG ++ V GGL Sbjct: 231 SYLTGQTIVVDGGL 244 >1H5Q-A nrPDB Length = 265 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 14/251 (5%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 +VTG GIG A + +A GA VA A A E +G KE + A+Q Sbjct: 18 IVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVG----KEFGVKTK--AYQC 71 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DVS ++Q+ A P S +++ AG++ + ++ +D+ V VN+ G F Sbjct: 72 DVSNTDIVTKTIQQIDADLG-PISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNT 130 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKV-------GNVGQTNYAASKAGVIGLTQTAAREL 187 +A A+ + +GSI+ SS+ ++ G++ Q Y +SKA L + A E Sbjct: 131 CRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEW 190 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 GIR N++ PG++ T T + +K+ D IP+ PE++ L S+ + Y Sbjct: 191 ASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDHATY 250 Query: 248 ITGTSVEVTGG 258 +TG + GG Sbjct: 251 MTGGEYFIDGG 261 >3OIC-A nrPDB Length = 258 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 117/250 (46%), Gaps = 16/250 (6%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAA-CDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 ALVTG+ G+G+A ++RLA G + + AA ET + G K Sbjct: 7 ALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVK-------VLVV 59 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCA-GITQDEFLLHMSEDDWDKVIAVNLKGT 131 +A+V + + + +Q+ F R V + A G+ + ++ + E WD + +N K Sbjct: 60 KANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRP--VMELEETHWDWTMNINAKAL 117 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNV-GQTNYAASKAGVIGLTQTAARELGRH 190 Q AA+ + NG G I++ISS+ G + + T SKA + LT+ A EL Sbjct: 118 LFCAQEAAKLMEKNGG-GHIVSISSL-GSIRYLENYTTVGVSKAALEALTRYLAVELSPK 175 Query: 191 GIRCNSVLPGFIATPMTQKVPQK--VVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 I N+V G I T + P + +++ + P G + + +D+ D V FL S + I Sbjct: 176 QIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMI 235 Query: 249 TGTSVEVTGG 258 G ++ V GG Sbjct: 236 RGQTIIVDGG 245 >3ZV3-A nrPDB Length = 281 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 79/267 (29%), Positives = 122/267 (45%), Gaps = 28/267 (10%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L +AL+TG SG+GRA+ R EGA VA LD++A E +R L E G Sbjct: 2 KLTGEVALITGGASGLGRALVDRFVAEGARVAV--LDKSA--ERLREL------EVAHGG 51 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD----WDKV 123 N DV + + E+ A F + +++ + L + ED +D + Sbjct: 52 NAVGVVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDI 111 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 VN+KG +A ALVS+ RGS++ S G N G Y A+K V+GL + Sbjct: 112 FHVNVKGYIHAVKACLPALVSS--RGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQM 169 Query: 184 ARELGRHGIRCNSVLPGFIAT----PMTQKVPQKVV------DKITEMIPMGHLGDPEDV 233 A EL H +R N V PG + T P + + ++ + D + ++P+G + E+ Sbjct: 170 AFELAPH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEY 228 Query: 234 ADVVAFLASE-DSGYITGTSVEVTGGL 259 F A+ DS TG + GG+ Sbjct: 229 TGAYVFFATRGDSLPATGALLNYDGGM 255 >5JY1-A nrPDB Length = 274 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 77/261 (29%), Positives = 125/261 (47%), Gaps = 21/261 (8%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAA---AQETVRLLGGPGSKEGPP 65 L +ALVTGAG GIGR V+ EGA V +++ + ++ +R +GG Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW-DKVI 124 + A+ +A A R +EQ + ++V+ A + LL D+ ++ + Sbjct: 72 VTSKASIEA------AVRSAVEQFGSL-----DILVNNAFVPTPNVLLEEKTDEMLEQTL 120 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 +L T+ +AA + G I+N SI + G +Y +KAG++GLT++AA Sbjct: 121 TTSLWATWWAMRAAFVPMRERRW-GRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAA 179 Query: 185 RELGRHGIRCNSVLP---GFIATPMTQKVPQKVVDKITEMIPMGHLGDPE-DVADVVAFL 240 E GR I N++ P G + K P+ ++ P+G GDPE D+ F Sbjct: 180 SEWGRFNITVNAIAPTAMGATFFELAAKNPE-FAERSAAARPLGRSGDPEQDIGPAAVFF 238 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 ASE S ++TG ++ V GGL + Sbjct: 239 ASEMSRFVTGETLHVDGGLHL 259 >2X9N-A nrPDB Length = 288 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 79/273 (28%), Positives = 124/273 (45%), Gaps = 28/273 (10%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + + + A+VTGA IGRA++V+L G V + + E L +KE R Sbjct: 19 SHMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVV---IHYHNSAEAAVSLADELNKE---R 72 Query: 67 GNHAAF-QADVSEARAARCLLEQV-QACFS---RPPSVVVSCAGITQDEFLLHMSEDDWD 121 N A QAD++ + E++ +CF R +V + + + ED+ + Sbjct: 73 SNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSN 132 Query: 122 ---------KVIAVNLKGTFLVTQAAAQAL--VSNGCRGS---IINISSIVGKVGNVGQT 167 ++I N FL+T + AQ + C S I+N+ + + + Sbjct: 133 GKTVETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFS 192 Query: 168 NYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHL 227 Y K ++GLTQ+AA EL +GIR N V PG P+ +K DK +P+G Sbjct: 193 LYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEK--DKWRRKVPLGRR 250 Query: 228 -GDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 E +AD V FL S + YITG+ ++V GGL Sbjct: 251 EASAEQIADAVIFLVSGSAQYITGSIIKVDGGL 283 >4FC7-A nrPDB Length = 277 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 71/261 (27%), Positives = 120/261 (45%), Gaps = 21/261 (8%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEG--ATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 LR +A +TG GSGIG ++ G +A+ L R +L G G + P Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR-KLAGATGRRCLP-- 81 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLH---MSEDDWDKV 123 DV A ++Q F R ++++CA FL +S + + V Sbjct: 82 -----LSMDVRAPPAVMAAVDQALKEFGRI-DILINCAA---GNFLCPAGALSFNAFKTV 132 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 + ++ GTF V++ + + G I+NI++ +G G Q + ++KA V +T+ Sbjct: 133 MDIDTSGTFNVSRVLYEKFFRDHG-GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 191 Query: 184 ARELGRHGIRCNSVLPGFIA-TPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 A E G IR NS+ PG I+ T +++ PQ + P+ LG+ ++A V +L Sbjct: 192 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 251 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 AS + Y+TG + GG ++ Sbjct: 252 ASPLASYVTGAVLVADGGAWL 272 >1W73-A nrPDB Length = 302 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 55/195 (28%), Positives = 98/195 (50%), Gaps = 12/195 (6%) Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAG--ITQDEFLLHMSEDDWDKVIAVNL 128 A Q DV + + + ++ P V+ + AG I+ E +S + W + + L Sbjct: 80 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTE---RLSPNAWKTITDIVL 136 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 GT VT + L+ + ++I++I + G+ A++KAGV ++++ A E G Sbjct: 137 NGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWG 196 Query: 189 RHGIRCNSVLPGFIATP--MTQKVPQKVVDKITEM---IPMGHLGDPEDVADVVAFLASE 243 ++G+R N + PG I T ++ P +K EM IP G LG E++A++ AFL S+ Sbjct: 197 KYGMRFNVIQPGPIKTKGAFSRLDPTGTFEK--EMIGRIPCGRLGTVEELANLAAFLCSD 254 Query: 244 DSGYITGTSVEVTGG 258 + +I G ++ GG Sbjct: 255 YASWINGAVIKFDGG 269 >4GKB-A nrPDB Length = 258 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 7/118 (5%) Query: 148 RGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM- 206 RG+I+NISS G + Y ASK + LT+ A L HG+R N+V+P + TP+ Sbjct: 132 RGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVMTPLY 191 Query: 207 -----TQKVPQKVVDKITEMIPMG-HLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 T + P+ + +I +P+G P+++AD FL S + + TG + V GG Sbjct: 192 RNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTGEWLFVDGG 249 >3U4C-A nrPDB Length = 281 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/267 (25%), Positives = 113/267 (42%), Gaps = 40/267 (14%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGAT--VAACDLDRAAAQETVR--LLGGPGSKEGPPRGNH 69 A V GA GIG+A++++LA + + + + +LD E+V+ +L P + Sbjct: 26 AFVMGASQGIGKAIALKLADQHFSLVINSRNLDNI---ESVKEDILAKH------PEASV 76 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 D+S+ + +++++ R ++ + G D F D ++ Sbjct: 77 IVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTF---------DNCNIEDMT 127 Query: 130 GTFLVTQAA-------AQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 TF A A +L+ G IINI + K + A +I ++ Sbjct: 128 ATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKN 187 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKV-----------PQKVVDKITEMIPMGHLGDPE 231 + +L H I N + PGFIAT + QK ++I IPM +G E Sbjct: 188 ISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAE 247 Query: 232 DVADVVAFLASEDSGYITGTSVEVTGG 258 + A + AFLASE++ YITG + GG Sbjct: 248 ETAALAAFLASEEASYITGQQISADGG 274 >1BDB-A nrPDB Length = 277 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 79/275 (28%), Positives = 122/275 (44%), Gaps = 44/275 (16%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACD--LDRAAAQETVRLLGGPGSKEGPP 65 +L+ L+TG SG+GRA+ R EGA VA D +R A ET G Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELET---------DHGD- 51 Query: 66 RGNHAAFQADVSEARAARCLLEQVQA---CFSRPPSV--VVSCAGI-TQDEFLLHMSEDD 119 N DV R L +Q QA C +R + ++ AGI L+ + E+ Sbjct: 52 --NVLGIVGDV------RSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEES 103 Query: 120 ----WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAG 175 +D+V +N+KG +A ALV++ RG++I S G N G Y A+K Sbjct: 104 LDAAFDEVFHINVKGYIHAVKACLPALVAS--RGNVIFTISNAGFYPNGGGPLYTAAKHA 161 Query: 176 VIGLTQTAARELGRHGIRCNSVLPGFIAT----PMTQKVPQKVV------DKITEMIPMG 225 ++GL + A EL + +R N V G I + P + + K + D + ++P+G Sbjct: 162 IVGLVRELAFELAPY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIG 220 Query: 226 HLGDPEDVADVVAFLASE-DSGYITGTSVEVTGGL 259 + + E+ F A+ D+ TG + GGL Sbjct: 221 RMPEVEEYTGAYVFFATRGDAAPATGALLNYDGGL 255 >5ILO-A nrPDB Length = 271 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 65/212 (30%), Positives = 96/212 (45%), Gaps = 21/212 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEG-ATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 R A+VTG GIG VS +L G A VA DL + +E V+L + P Sbjct: 13 FRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDL-QDNLEEFVKL------RAAHPTQ 65 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + + DV+ + E++ F +VV+ AGI D+ D + + VN Sbjct: 66 SVMIIKMDVANKKGVEATYEEIAKTFGN-IDIVVNVAGIFNDK--------DVQRTLLVN 116 Query: 128 LKGTFLVTQAAAQAL-VSNGCRGSI-INISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 L G T +A + NG +G I +N+SS+VG Y A+KAG+I T+ A Sbjct: 117 LGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLAN 176 Query: 186 E--LGRHGIRCNSVLPGFIATPMTQKVPQKVV 215 E R GI+ +V PG T M +K++ Sbjct: 177 EKYYQRSGIKFVTVCPGATMTDMFTNFTEKII 208 >1P33-A nrPDB Length = 289 Score = 64.3 bits (155), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 48/148 (32%), Positives = 72/148 (48%), Gaps = 13/148 (8%) Query: 122 KVIAVNLKGT-----FLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAA 171 +V A +L G+ + + +A AQ + G SI+N+ + +G T Y Sbjct: 138 EVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQPLLGYTMYTM 197 Query: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDP- 230 +K + GLT++AA EL IR N V PG P +P V + +P+ Sbjct: 198 AKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--DDMPFSVQEDYRRKVPLYQRNSSA 255 Query: 231 EDVADVVAFLASEDSGYITGTSVEVTGG 258 E+V+DVV FL S + YITGT ++V GG Sbjct: 256 EEVSDVVIFLCSPKAKYITGTCIKVDGG 283 >2BFA-A nrPDB Length = 288 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 82/287 (28%), Positives = 121/287 (42%), Gaps = 47/287 (16%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-A 71 +ALVTGA +GR+++ L EG A C +A E L ++ R N A Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEG--YAVCLHYHRSAAEANALSATLNAR----RPNSAIT 61 Query: 72 FQADVSEARAA---------------RCLLEQVQACFSR--PPSVVVSCAGITQDEFLLH 114 QAD+S A RC E V AC++ V+V+ A LL Sbjct: 62 VQADLSNVATAPVSGADGSAPVTLFTRCA-ELVAACYTHWGRCDVLVNNASSFYPTPLLR 120 Query: 115 MSEDDWDKVI---------AVNLKGT-----FLVTQAAAQALV-----SNGCRGSIINIS 155 ED + + +L G+ + + +A A + G SIIN+ Sbjct: 121 NDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMV 180 Query: 156 SIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV 215 + +G T Y +K + GLT++AA EL IR N V PG + + +P V Sbjct: 181 DAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVW 238 Query: 216 DKITEMIPMGHL-GDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 + +P+ +V+DVV FL S + YITGT V+V GG + Sbjct: 239 EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >2QHX-A nrPDB Length = 328 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 82/287 (28%), Positives = 121/287 (42%), Gaps = 47/287 (16%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-A 71 +ALVTGA +GR+++ L EG A C +A E L ++ R N A Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEG--YAVCLHYHRSAAEANALSATLNAR----RPNSAIT 101 Query: 72 FQADVSEARAA---------------RCLLEQVQACFSR--PPSVVVSCAGITQDEFLLH 114 QAD+S A RC E V AC++ V+V+ A LL Sbjct: 102 VQADLSNVATAPVSGADGSAPVTLFTRCA-ELVAACYTHWGRCDVLVNNASSFYPTPLLR 160 Query: 115 MSEDDWDKVI---------AVNLKGT-----FLVTQAAAQALV-----SNGCRGSIINIS 155 ED + + +L G+ + + +A A + G SIIN+ Sbjct: 161 NDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMV 220 Query: 156 SIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVV 215 + +G T Y +K + GLT++AA EL IR N V PG + + +P V Sbjct: 221 DAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVW 278 Query: 216 DKITEMIPMGHL-GDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 + +P+ +V+DVV FL S + YITGT V+V GG + Sbjct: 279 EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >4HBG-A nrPDB Length = 286 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 63/269 (23%), Positives = 115/269 (42%), Gaps = 41/269 (15%) Query: 13 LALVTGAGSGIGRAVSVRLAGEG----------ATVAACDLDRAAAQETVRLLG----GP 58 +A+VTGA GIG+A+ +L +G ++ +DR Q + Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 59 GSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRP------------PSVVVSCAGI 106 K+ P ++ ++ D E R L+Q + P +++++CAG+ Sbjct: 66 DFKKWPHWLDYESY--DGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 Query: 107 TQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSN----------GCRGSIINISS 156 TQ+ + + ++ VN +T + ++ + R +I+NISS Sbjct: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 Query: 157 IV--GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIA-TPMTQKVPQK 213 I+ GK+ G + Y+ASKA + T+ A E+ IRC ++ PG + T M Q +P + Sbjct: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 Query: 214 VVDKITEMIPMGHLGDPEDVADVVAFLAS 242 + + I P ++A+ V L S Sbjct: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYS 272 >4DRY-A nrPDB Length = 281 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 12/174 (6%) Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DV + L V+A F+R +V + L ++ + W+ ++A NL G FL Sbjct: 91 DVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLC 150 Query: 135 TQAAAQALVSNGCRG-SIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 TQ A + + + RG IIN SI + Y A+K + GLT++ A + H I Sbjct: 151 TQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIA 210 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEM-----IPMGHLGDPEDVADVVAFLAS 242 C + G AT MT ++ V+ E+ IP+ H +A+ V ++AS Sbjct: 211 CGQIDIGNAATDMTARMSTGVLQANGEVAAEPTIPIEH------IAEAVVYMAS 258 >4RGB-A nrPDB Length = 294 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 41/280 (14%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL------------DRAAAQETVRLLG 56 L + +TGA G GR+ +V A +GA + D+ +ET RL+ Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 57 GPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMS 116 G + +ADV + + + + F +V+ + AG+ L + Sbjct: 83 KTGQE-------MLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIAN-AGVV----LTNPD 130 Query: 117 EDDWDKVIAVNLK----GTFLVTQAAAQALVSNGCRGSIINISSIVGKV----GNVGQTN 168 E D + + + L G + Q A + G G++I SS++ + G G Sbjct: 131 ERDASEALRLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDA 190 Query: 169 YAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP---------QKVVDKIT 219 Y SK + GL ++ A L IR N V P +TPM + P +V+ ++ Sbjct: 191 YLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMS 250 Query: 220 EMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 +P + +P DV++ + FL S+ TG+ ++V G+ Sbjct: 251 TALPDFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >1FJH-A nrPDB Length = 257 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 3/98 (3%) Query: 165 GQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMI 222 G YA SK + + A G G+R N++ PG TP+ Q Q + + I + + Sbjct: 151 GNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFV 210 Query: 223 P-MGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 P MG +P ++A V+AFL S + Y+ G + + GG+ Sbjct: 211 PPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGI 248 >2NWQ-A nrPDB Length = 272 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 1/138 (0%) Query: 118 DDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVI 177 DDWD ++ N+KG T+ L+++G SI+N+ S+ GK G Y +KA V Sbjct: 120 DDWDTMVDTNIKGLLYSTRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVE 179 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVV 237 + +L G+R ++ PG + + + + H PED+A+ + Sbjct: 180 QFSLNLRCDLQGTGVRVTNLEPGLCESEFSLVRFGGDQARYDKTYAGAHPIQPEDIAETI 239 Query: 238 AFLASEDSGYITGTSVEV 255 ++ ++ + ++ S+E+ Sbjct: 240 FWIMNQPA-HLNINSLEI 256 >3RKU-A nrPDB Length = 287 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 58/243 (23%), Positives = 101/243 (41%), Gaps = 19/243 (7%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQ-ETVRLLGGPGSKEGPPR 66 RL L+TGA +GIG+A ++ A+ L AA + E + L +E P Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLE--ASNGDMKLILAARRLEKLEELKKTIDQEFPNA 87 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 H A Q D+++A + +E + F +V + + + ++ +D V Sbjct: 88 KVHVA-QLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDT 146 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 N+ +TQA + G I+N+ SI G+ + Y ASK V T + +E Sbjct: 147 NVTALINITQAVLPIFQAKNS-GDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKE 205 Query: 187 LGRHGIRCNSVLPGFIATPMT-------QKVPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 L IR + PG + T + ++ + V T ++ +DVAD++ + Sbjct: 206 LINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLM-------ADDVADLIVY 258 Query: 240 LAS 242 S Sbjct: 259 ATS 261 >2DKN-A nrPDB Length = 255 Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 5/100 (5%) Query: 165 GQTN--YAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQ--KVPQKVVDKITE 220 GQT+ YA SK V L + + G+R N V PG + TP+ Q K + + Sbjct: 147 GQTHLAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRR 206 Query: 221 MI-PMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 + P+G +P +VA+ +AFL + +I G+ + V GG+ Sbjct: 207 FVAPLGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGM 246 >3PXX-A nrPDB Length = 287 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 75/286 (26%), Positives = 109/286 (38%), Gaps = 39/286 (13%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-----DRAAAQETVRLLGGPGSK- 61 R++ + LVTG G GR+ +V+LA EGA + D+ T R L G + Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWD 121 E R + A + DV + A L A F + VVV+ AGI H+ + Sbjct: 67 EKTGRKAYTA-EVDVRDRAAVSRELANAVAEFGK-LDVVVANAGIC--PLGAHLPVQAFA 122 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-----------GNVGQTNYA 170 V+ G AA L S SII S+ G + G Y+ Sbjct: 123 DAFDVDFVGVINTVHAALPYLTSG---ASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYS 179 Query: 171 ASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ-----------KVVDKIT 219 +K V T A +L IR N + P + T M P D + Sbjct: 180 YAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALL 239 Query: 220 EMIPMGHLGDP----EDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 M + P D+++ V FLAS++S Y+TG +V G + Sbjct: 240 AFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >3OIG-A nrPDB Length = 266 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 4/126 (3%) Query: 138 AAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSV 197 AA+ +++ G GSI+ ++ + G++ +KA + + A +LG+ IR NS+ Sbjct: 132 AARPMMTEG--GSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSI 189 Query: 198 LPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEV 255 G I T + + ++ I E P+ PE+V D AFL S+ S ITG ++ V Sbjct: 190 SAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHV 249 Query: 256 TGGLFM 261 G + Sbjct: 250 DSGFHI 255 >6CGE-A nrPDB Length = 328 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 92/206 (44%), Gaps = 8/206 (3%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 L+TG SGIG ++VRLA + + + RL + PP G+ Q Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPP-GSLETLQL 65 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DV ++++ E+V V+V AG+ L + ED V+ VN+ GT + Sbjct: 66 DVRDSKSVAAARERVTEGRV---DVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 QA + G G ++ S+ G +G Y ASK + GL ++ A L G+ Sbjct: 123 LQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 Query: 195 NSVLPGFIATPMTQKV---PQKVVDK 217 + + G + T +KV P++V+D+ Sbjct: 182 SLIECGPVHTAFMEKVLGSPEEVLDR 207 >1A27-A nrPDB Length = 289 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 92/206 (44%), Gaps = 8/206 (3%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 L+TG SGIG ++VRLA + + + RL + PP G+ Q Sbjct: 6 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPP-GSLETLQL 64 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DV ++++ E+V V+V AG+ L + ED V+ VN+ GT + Sbjct: 65 DVRDSKSVAAARERVTEGRV---DVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 QA + G G ++ S+ G +G Y ASK + GL ++ A L G+ Sbjct: 122 LQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 195 NSVLPGFIATPMTQKV---PQKVVDK 217 + + G + T +KV P++V+D+ Sbjct: 181 SLIECGPVHTAFMEKVLGSPEEVLDR 206 >2YW9-A nrPDB Length = 261 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 108/256 (42%), Gaps = 26/256 (10%) Query: 14 ALVTGAGS--GIGRAVSVRLAGEGATVA---ACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 ALV G + +G A++ +L GA VA + R A++ LGG Sbjct: 11 ALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGA---------- 60 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF---LLHMSEDDWDKVIA 125 F+ADV++ L V+ F +V + A ++ + DW ++A Sbjct: 61 -LLFRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDW--LLA 117 Query: 126 VNLKGTFLVTQAA-AQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 + + LV A A+ L+ G G I+ ++ + A +KA + + A Sbjct: 118 LEVSAYSLVAVARRAEPLLREG--GGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLA 175 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 ELG G+R N++ G + T + +P K+ D++ + P+ E+V ++ FL S Sbjct: 176 YELGPKGVRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLS 235 Query: 243 EDSGYITGTSVEVTGG 258 + ITG V V G Sbjct: 236 PLASGITGEVVYVDAG 251 >3E9N-A nrPDB Length = 245 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 81/158 (51%), Gaps = 11/158 (6%) Query: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQAL-VSNGCRGSIINISSIV 158 +V A + +D + S +W + +N+ +++ AL ++GC +I I+S Sbjct: 79 LVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLPALRAASGC---VIYINSGA 135 Query: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKI 218 G + G T YAASK + GL +E +GIR ++V PG TPM Q + + + Sbjct: 136 GNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGPTNTPMLQGL---MDSQG 192 Query: 219 TEMIPMGHLGDPEDVADVVAFLASEDSGYITG-TSVEV 255 T P ++ +P+++A+ + F+ D+G T T+V+V Sbjct: 193 TNFRPEIYI-EPKEIANAIRFVI--DAGETTQITNVDV 227 >5YCX-A nrPDB Length = 266 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 48/194 (24%), Positives = 78/194 (40%), Gaps = 29/194 (14%) Query: 87 EQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNG 146 E++ ACF V + G+ + + DD LKG F+ T L N Sbjct: 73 EELTACFETIKQEVGTIHGVAH--CIAFANRDD--------LKGEFVDTSRDGFLLAQNI 122 Query: 147 CRGSIINISSIVGKV----GNVGQTNY-------------AASKAGVIGLTQTAARELGR 189 S+ ++ KV GN+ Y +KA + + A +LG+ Sbjct: 123 SAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQ 182 Query: 190 HGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 HGIR N++ G I T + V ++ +I E P+ E+V D FL S+ + Sbjct: 183 HGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLARG 242 Query: 248 ITGTSVEVTGGLFM 261 +TG ++ V G + Sbjct: 243 VTGENIHVDSGYHI 256 >3UCF-A nrPDB Length = 223 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 8/96 (8%) Query: 170 AASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP----MTQKVPQKVVDKITEMIPMG 225 AA A + T+ A+EL IR N++ PG T M + + +P+G Sbjct: 131 AAINAAIEATTKVLAKELAP--IRVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVG 188 Query: 226 HLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 +G+ D+A +A+L + + Y+TGT ++V GG + Sbjct: 189 KVGEASDIA--MAYLFAIQNSYMTGTVIDVDGGALL 222 >5CFZ-A nrPDB Length = 305 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 19/204 (9%) Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 G+ Q DV+E + + ++ + + V S D+ D D V AV Sbjct: 99 GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL-------DGDYVNAV 151 Query: 127 NLKGTFLVTQAAAQALVS--NGCRGSIINISSIVGKVGNVGQT----NY---AASKAGVI 177 +G + ++ + V+ CR S++N S + + +G NY +KA + Sbjct: 152 TREGFKIAHDISSYSFVAMAKACR-SMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLE 210 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVAD 235 + A +G G+R N++ G I T + +K++ + P+ EDV + Sbjct: 211 ANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGN 270 Query: 236 VVAFLASEDSGYITGTSVEVTGGL 259 AFL S+ S I+G V V GG Sbjct: 271 SAAFLCSDLSAGISGEVVHVDGGF 294 >4JQC-A nrPDB Length = 282 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 19/204 (9%) Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 G+ Q DV+E + + ++ + + V S D+ D D V AV Sbjct: 76 GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL-------DGDYVNAV 128 Query: 127 NLKGTFLVTQAAAQALVS--NGCRGSIINISSIVGKVGNVGQT----NY---AASKAGVI 177 +G + ++ + V+ CR S++N S + + +G NY +KA + Sbjct: 129 TREGFKIAHDISSYSFVAMAKACR-SMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLE 187 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVAD 235 + A +G G+R N++ G I T + +K++ + P+ EDV + Sbjct: 188 ANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGN 247 Query: 236 VVAFLASEDSGYITGTSVEVTGGL 259 AFL S+ S I+G V V GG Sbjct: 248 SAAFLCSDLSAGISGEVVHVDGGF 271 >1SNY-A nrPDB Length = 267 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Query: 148 RGSIINISSIVGKV-GNV--GQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204 R +IIN+SSI+G + GN G Y SK+ + T++ + +L I C S+ PG++ T Sbjct: 165 RAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSLSVDLYPQRIMCVSLHPGWVKT 224 Query: 205 PM 206 M Sbjct: 225 DM 226 >4M89-A nrPDB Length = 261 Score = 36.2 bits (82), Expect = 0.013, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 2/74 (2%) Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLASED 244 LG+ GIRCN + G I T + K++ + P+ E+V + AFL S+ Sbjct: 178 LGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDL 237 Query: 245 SGYITGTSVEVTGG 258 S ITG V GG Sbjct: 238 SSGITGEITYVDGG 251 >2P91-A nrPDB Length = 285 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%) Query: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGD 229 +KA + + A ++ +HG R N++ G + T + +++ T++ P G Sbjct: 177 AKAALESTVRYLAYDIAKHGHRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPIT 236 Query: 230 PEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 EDV D FL S+ + ITG V V G + Sbjct: 237 IEDVGDTAVFLCSDWARAITGEVVHVDNGYHI 268 >3DWF-A nrPDB Length = 276 Score = 35.8 bits (81), Expect = 0.020, Method: Compositional matrix adjust. Identities = 45/174 (25%), Positives = 74/174 (42%), Gaps = 11/174 (6%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETV-RLLGGPGSKEGPPRGNHAAFQ 73 +VTGA GIGR ++ LA GA V + A Q+ V R L + G ++ A Sbjct: 15 IVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCL-----ELGAASAHYIA-- 67 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 + + A + + ++++ + F H D+ K + VN +F+ Sbjct: 68 GSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTF-FHGEIDNVRKSMEVNFH-SFV 125 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 V AA ++ +GSI +SS+ GK+ Y+ASK + G T E Sbjct: 126 VLSVAAMPMLMQ-SQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEF 178 >4J3F-A nrPDB Length = 280 Score = 34.7 bits (78), Expect = 0.039, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGD 229 +KA + + A LG GI+ N+V G I T + +K++D + P+ D Sbjct: 182 AKASLEATVRYTALALGEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVD 241 Query: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258 +V + VAFL S+ + ITG V V G Sbjct: 242 IMEVGNTVAFLCSDMATGITGEVVHVDAG 270 >1B15-A nrPDB Length = 254 Score = 34.7 bits (78), Expect = 0.043, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 12/147 (8%) Query: 65 PRGNHAAFQADVSEARA-ARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 P+ N DV+ A ++ LL+++ + ++++ AGI D H E + Sbjct: 53 PKVNITFHTYDVTVPVAESKKLLKKIFDQL-KTVDILINGAGILDD----HQIE----RT 103 Query: 124 IAVNLKGTFLVTQAAAQALVSN--GCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 IA+N G T A G G I NI S+ G Y+ASKA V+ T Sbjct: 104 IAINFTGLVNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTN 163 Query: 182 TAARELGRHGIRCNSVLPGFIATPMTQ 208 + A+ G+ S+ PG TP+ Sbjct: 164 SLAKLAPITGVTAYSINPGITRTPLVH 190 >2QE0-A nrPDB Length = 475 Score = 34.3 bits (77), Expect = 0.062, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 G G RC +V + + V ++V+KI E + +G+PED AD+ + ++ + Sbjct: 277 FGYSGQRCTAVKRVLV----MESVADELVEKIREKVLALTIGNPEDDADITPLIDTKSAD 332 Query: 247 YITG 250 Y+ G Sbjct: 333 YVEG 336 >4Q9N-A nrPDB Length = 298 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Query: 171 ASKAGVIGLTQTAARELGRH-GIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHL 227 A+KA + T+ A E GR G+R N++ G +A+ + + +++VD + P+ Sbjct: 194 AAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGFIERMVDYYQDWAPLPSP 253 Query: 228 GDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 + E V AFL S + ITG ++ V G Sbjct: 254 MEAEQVGAAAAFLVSPLASAITGETLYVDHG 284 >4ALL-A nrPDB Length = 277 Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust. Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 139 AQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVL 198 A+ L+ G GSI+ + + G+ +KA + + A +LG IR N++ Sbjct: 153 AKKLMPEG--GSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAIS 210 Query: 199 PGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVT 256 G I T + V ++ +I E P+ D +V A+L S+ S +TG ++ V Sbjct: 211 AGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVD 270 Query: 257 GGL 259 G Sbjct: 271 SGF 273 >4Z3K-A nrPDB Length = 275 Score = 31.6 bits (70), Expect = 0.36, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 58/141 (41%), Gaps = 9/141 (6%) Query: 121 DKVIAVNLKGTFLVTQAAAQALV-SNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + A+NL +T + +A S G +++NISS+ G Y A KA L Sbjct: 135 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 194 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDK-----ITEMIPMGHLGDPEDVA 234 Q A E +R + PG + T M Q + VD + E+ G L D + A Sbjct: 195 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 252 Query: 235 DVVAFLASEDSGYITGTSVEV 255 + L +D + +G V+ Sbjct: 253 QKLLSLLEKDE-FKSGAHVDF 272 >5TQV-A nrPDB Length = 233 Score = 31.6 bits (70), Expect = 0.40, Method: Compositional matrix adjust. Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 7/112 (6%) Query: 98 SVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSI 157 +VVVS + E + ++ DD+D V+ N++G + LV + RG + +SS Sbjct: 82 AVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILL-PLVED-ARGVLAVVSSR 139 Query: 158 VGKVGNVGQTN---YAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206 +G + T Y ASKA + + + A+ + RH C S+ PG++ T M Sbjct: 140 MGSISEATGTTGWLYRASKAALNDVLRIASLQT-RHAA-CISLHPGWVRTDM 189 >4HWK-A nrPDB Length = 288 Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust. Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 9/140 (6%) Query: 121 DKVIAVNLKGTFLVTQAAAQALV-SNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + A+NL +T + +A S G +++NISS+ G Y A KA L Sbjct: 148 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 207 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDK-----ITEMIPMGHLGDPEDVA 234 Q A E +R + PG + T M Q + VD + E+ G L D + A Sbjct: 208 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 265 Query: 235 DVVAFLASEDSGYITGTSVE 254 + L +D + +G V+ Sbjct: 266 QKLLSLLEKDE-FKSGAHVD 284 >5PGZ-A nrPDB Length = 276 Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 13/175 (7%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETV-RLLGGPGSKEGPPRGNHAAFQ 73 +VTGA GIGR ++ L+ GA V Q+ V R L + G ++ A Sbjct: 22 IVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCL-----ELGAASAHYIA-- 74 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF-LLHMSEDDWDKVIAVNLKGTF 132 + + A + + ++++ ITQ L H +V+ VN Sbjct: 75 GTMEDMTFAEQFIVKAGKLMGGLDMLILN--HITQTSLSLFHDDIHSVRRVMEVNFLSYV 132 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 +++ AA L GSI ISS+ GK+ Y+ASK + G T EL Sbjct: 133 VMSTAALPML--KQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 >2HRB-A nrPDB Length = 274 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 20/152 (13%) Query: 11 SALALVTGAGSGIGRAVSVRLAGE-GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 S +ALVTGA GIG A++ L + V D A Q V+ L G PR + Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLS---PRFH- 57 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD---WDKVIAV 126 Q D+ + ++ R L + ++ + +V+V+ A + DD +D + Sbjct: 58 ---QLDIDDLQSIRALRDFLRKEYG-GLNVLVNNAAVA-------FKSDDPMPFDIKAEM 106 Query: 127 NLKGTFLVTQAAAQALVS-NGCRGSIINISSI 157 LK F T+ L+ G ++NISS+ Sbjct: 107 TLKTNFFATRNMCNELLPIMKPHGRVVNISSL 138 >1ENP-A nrPDB Length = 312 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 13/98 (13%) Query: 170 AASKAGVIGLTQTAARELGR-HGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLG 228 +++KA + T+ A E GR IR N++ G P+ + K + I MI + Sbjct: 203 SSAKAALESDTRVLAFEAGRKQNIRVNTISAG----PLGSRA-AKAIGFIDTMIEYSYNN 257 Query: 229 DP-------EDVADVVAFLASEDSGYITGTSVEVTGGL 259 P ++V + AFL S + ITG ++ V GL Sbjct: 258 APIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGL 295 >2NTV-A nrPDB Length = 268 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 13/100 (13%) Query: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV------------PQKVVDKIT 219 +K+ + + + ARE G++G+R N V G I T + Q + + Sbjct: 163 AKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWD 222 Query: 220 EMIPMG-HLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 + P+G ++ DP VA V L SE TG+ + GG Sbjct: 223 QRAPIGWNMKDPTPVAKTVCALLSEWLPATTGSIIYADGG 262 >3PRL-A nrPDB Length = 505 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 4/60 (6%) Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 G RC ++ F+ V ++V I E++ +G PED AD+ + + + +I G Sbjct: 290 GQRCTAIKRVFV----QDSVADQLVANIKELVEQLTVGSPEDDADITPVIDEKSAAFIQG 345 >5TY0-A nrPDB Length = 422 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 5/58 (8%) Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADV 236 T+ ++ RH N V+P F + K Q V+D + E +P P D+ D+ Sbjct: 244 FTEAEIKKALRHLTITNKVVPVFCGSAFKNKGVQAVLDGVIEYLP-----SPTDIPDI 296 >4ZJU-A nrPDB Length = 275 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Query: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQ--KVPQKVVDKITEMIPMGHLGD 229 +KA + + A LG GIR N++ G I T K +K++D ++ P+ Sbjct: 173 AKASLEAGVRYLASSLGVDGIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVT 232 Query: 230 PEDVADVVAFLASEDSGYITGTSVEVTGGL 259 E+V + FL S + ITG + V G Sbjct: 233 IEEVGNAALFLCSPWASGITGEILYVDAGF 262 >4NR0-A nrPDB Length = 273 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 2/138 (1%) Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 IA ++ + A A + G GS++ +S + + +KA + + Sbjct: 117 IAHDISAYSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYL 176 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQ--KVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A LG G R N+V G I T K +K++ P+ E+V + AFL Sbjct: 177 AGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLC 236 Query: 242 SEDSGYITGTSVEVTGGL 259 S+ + I+G + V GG Sbjct: 237 SDLASGISGEILYVDGGF 254 >1EDZ-A nrPDB Length = 320 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD 44 NRL +V +GR ++ LA +GATV + D++ Sbjct: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 >3IC6-A nrPDB Length = 223 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%) Query: 161 VGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP 211 +GN+ S IG A + +G H R V P +ATPMT+ P Sbjct: 15 LGNIRIILTRTSHPANIGSAARAMKTMGLH--RLTIVTPNLMATPMTENPP 63 >3SLK-A nrPDB Length = 795 Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 81 AARCLLEQVQACF--SRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAA 138 A R L +V A P + VV AG+ D ++ + D+V+ + G + + Sbjct: 594 ADRETLAKVLASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLLE-- 651 Query: 139 AQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 L+ +++ SS+ G +G+ GQ NYAA+ + + L Q Sbjct: 652 ---LIDPDV--ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQ 689 >2YIB-A nrPDB Length = 853 Score = 28.1 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 203 ATPMTQKVPQKVVDKITEMIPMGHLGDPE 231 A P T + P+K +D++T I G DP+ Sbjct: 694 ARPQTPRSPKKTLDEVTTAITSGTYKDPK 722 >5L51-A nrPDB Length = 324 Score = 28.1 bits (61), Expect = 4.5, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 5/96 (5%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQET-VRLLGGPGSKEGPPRGNHAA 71 A+VTGA GIG + +LA +G TV D E RL+ GS+ G + Sbjct: 17 YAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQ-- 74 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGIT 107 Q DV++ + L++ ++ F ++V+ AG+ Sbjct: 75 -QLDVADPASVAALVDFIKTKFGS-LDILVNNAGLN 108 >1OAA-A nrPDB Length = 259 Score = 28.1 bits (61), Expect = 4.5, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 3/89 (3%) Query: 121 DKVIAVNLKGTFLVTQAAAQALV-SNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + A+NL +T A S G +++NISS+ G Y A KA L Sbjct: 120 NNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 179 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQ 208 Q A E +R S PG + M Q Sbjct: 180 YQVLAAE--EPSVRVLSYAPGPLDNDMQQ 206 >1Z45-A nrPDB Length = 699 Score = 27.7 bits (60), Expect = 4.7, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRL 54 M +QLQ+ S + LVTG IG V L G V A +L + RL Sbjct: 1 MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARL 55 >3U9L-A nrPDB Length = 324 Score = 27.3 bits (59), Expect = 7.4, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 19/36 (52%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD 44 + + L+TGA SG GR + LAG G V A D Sbjct: 3 MSKKIILITGASSGFGRLTAEALAGAGHRVYASMRD 38 >2UVV-A nrPDB Length = 358 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 9/61 (14%) Query: 162 GNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEM 221 G V NY A K GV + G + +LP + PM ++V Q+V +I + Sbjct: 47 GAVATANYEARKFGV---------KAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNL 97 Query: 222 I 222 + Sbjct: 98 L 98 >1W4Y-A nrPDB Length = 323 Score = 26.9 bits (58), Expect = 10.0, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 37 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARA 81 TV+ DL AAQ++V L GGP + P G + QA + A A Sbjct: 94 TVSCADLLTIAAQQSVTLAGGPSWRV--PLGRRDSLQAFLDLANA 136 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4CQL-A nrPDB 329 8e-91 2PNF-A nrPDB 290 4e-79 4JRO-A nrPDB 289 1e-78 2UVD-A nrPDB 286 6e-78 3OSU-A nrPDB 285 2e-77 2HQ1-A nrPDB 282 9e-77 2C07-A nrPDB 280 3e-76 3RSH-A nrPDB 278 2e-75 3FTP-A nrPDB 273 6e-74 3LYL-A nrPDB 272 9e-74 1Q7C-A nrPDB 268 1e-72 3EMK-A nrPDB 268 2e-72 5CDY-A nrPDB 267 3e-72 4M8S-A nrPDB 265 1e-71 4BO1-A nrPDB 265 2e-71 3WOH-A nrPDB 264 2e-71 3F9I-A nrPDB 261 2e-70 4DMM-A nrPDB 261 2e-70 2PH3-A nrPDB 261 3e-70 3GRP-A nrPDB 259 8e-70 4NBT-A nrPDB 258 1e-69 4KMS-A nrPDB 258 2e-69 4NBV-A nrPDB 255 1e-68 1GEE-A nrPDB 255 1e-68 3OEC-A nrPDB 254 3e-68 2CDH-G nrPDB 254 3e-68 4K6F-A nrPDB 253 4e-68 3AUT-A nrPDB 253 4e-68 5ITV-A nrPDB 253 5e-68 2NM0-A nrPDB 253 7e-68 4RZH-A nrPDB 252 8e-68 3EZL-A nrPDB 252 1e-67 1GEG-A nrPDB 252 1e-67 3VZS-A nrPDB 248 1e-66 5VT6-A nrPDB 247 5e-66 6CI9-A nrPDB 247 5e-66 3O4R-A nrPDB 245 2e-65 5OVL-A nrPDB 244 2e-65 4IIN-A nrPDB 244 3e-65 1AE1-A nrPDB 244 3e-65 2EW8-A nrPDB 243 5e-65 4Z9Y-A nrPDB 243 5e-65 6NRP-A nrPDB 243 7e-65 3UVE-A nrPDB 242 1e-64 2AE2-A nrPDB 241 3e-64 1YXM-A nrPDB 239 7e-64 5OVJ-A nrPDB 239 9e-64 1NFF-A nrPDB 238 2e-63 4IIV-A nrPDB 238 2e-63 4IS3-A nrPDB 238 2e-63 3WYE-A nrPDB 238 3e-63 5T5Q-A nrPDB 237 4e-63 3WTC-A nrPDB 237 6e-63 5U9P-A nrPDB 234 2e-62 1UZM-A nrPDB 234 2e-62 3T7C-A nrPDB 233 4e-62 2ZAT-A nrPDB 233 4e-62 4CQM-B nrPDB 232 1e-61 3RWB-A nrPDB 231 3e-61 4RZI-B nrPDB 230 5e-61 2Q2Q-A nrPDB 229 8e-61 5OJG-A nrPDB 228 2e-60 3W8F-A nrPDB 228 2e-60 5EJ2-A nrPDB 228 2e-60 4DBZ-A nrPDB 227 3e-60 1K2W-A nrPDB 227 4e-60 1X1T-A nrPDB 227 5e-60 4HP8-A nrPDB 225 1e-59 3V2H-A nrPDB 225 2e-59 4E6P-A nrPDB 224 3e-59 3V2G-A nrPDB 223 8e-59 3A28-C nrPDB 222 1e-58 5YSS-A nrPDB 222 1e-58 4MOW-A nrPDB 220 3e-58 3U5T-A nrPDB 220 6e-58 2CFC-A nrPDB 218 2e-57 3D3W-A nrPDB 218 2e-57 1AHH-A nrPDB 216 5e-57 3R3S-A nrPDB 216 8e-57 1O5I-A nrPDB 214 2e-56 3UF0-A nrPDB 213 5e-56 2HSD-A nrPDB 213 5e-56 2B4Q-A nrPDB 213 8e-56 1DOH-A nrPDB 213 9e-56 5B1Y-A nrPDB 212 1e-55 1CYD-A nrPDB 212 1e-55 3OIC-A nrPDB 212 1e-55 5O3Z-A nrPDB 210 6e-55 3GDF-A nrPDB 210 7e-55 1H5Q-A nrPDB 208 2e-54 4AVY-A nrPDB 206 8e-54 1HXH-A nrPDB 206 9e-54 4TRR-A nrPDB 206 9e-54 4FC7-A nrPDB 203 4e-53 2O23-A nrPDB 203 7e-53 2AG5-A nrPDB 203 8e-53 4RGB-A nrPDB 198 3e-51 1E3W-A nrPDB 197 5e-51 2GDZ-A nrPDB 196 9e-51 2FWM-X nrPDB 195 2e-50 4EGF-A nrPDB 193 6e-50 5JS6-A nrPDB 193 7e-50 3UN1-A nrPDB 193 7e-50 3V8B-A nrPDB 192 1e-49 3U4C-A nrPDB 191 3e-49 3PXX-A nrPDB 190 6e-49 2X9N-A nrPDB 189 8e-49 5JY1-A nrPDB 188 3e-48 3OML-A nrPDB 186 1e-47 3ZV3-A nrPDB 185 2e-47 4CR6-A nrPDB 184 4e-47 1BDB-A nrPDB 178 2e-45 4DA9-A nrPDB 178 3e-45 2QHX-A nrPDB 176 8e-45 2BFA-A nrPDB 176 1e-44 1P33-A nrPDB 176 1e-44 2BGM-A nrPDB 175 2e-44 5IZ4-A nrPDB 175 2e-44 1W73-A nrPDB 173 5e-44 2NWQ-A nrPDB 168 2e-42 2YW9-A nrPDB 165 2e-41 4GKB-A nrPDB 165 2e-41 3PPI-A nrPDB 164 4e-41 3RKU-A nrPDB 159 8e-40 4HBG-A nrPDB 159 9e-40 1A27-A nrPDB 158 2e-39 4DRY-A nrPDB 158 3e-39 6CGE-A nrPDB 157 4e-39 5ILO-A nrPDB 152 2e-37 3OIG-A nrPDB 148 2e-36 5YCX-A nrPDB 147 4e-36 3E9N-A nrPDB 133 6e-32 2DKN-A nrPDB 124 3e-29 3UCF-A nrPDB 118 3e-27 1FJH-A nrPDB 117 5e-27 Sequences not found previously or not previously below threshold: 2P91-A nrPDB 158 2e-39 4ALL-A nrPDB 137 6e-33 5KOI-A nrPDB 135 2e-32 4ZJU-A nrPDB 129 1e-30 4M89-A nrPDB 128 2e-30 5TF4-A nrPDB 127 5e-30 5CFZ-A nrPDB 127 6e-30 3GRK-A nrPDB 127 6e-30 4J3F-A nrPDB 126 9e-30 4NR0-A nrPDB 126 1e-29 4JQC-A nrPDB 126 1e-29 3K2E-A nrPDB 125 2e-29 5I9N-A nrPDB 123 6e-29 4NK4-A nrPDB 119 1e-27 2HRB-A nrPDB 114 3e-26 3DWF-A nrPDB 111 4e-25 3KZV-A nrPDB 109 1e-24 2PD3-A nrPDB 108 3e-24 5L51-A nrPDB 106 7e-24 5PGZ-A nrPDB 106 8e-24 4Q9N-A nrPDB 106 1e-23 1N5D-A nrPDB 105 2e-23 3O26-A nrPDB 102 1e-22 3BHI-A nrPDB 102 1e-22 1ENP-A nrPDB 101 4e-22 1SNY-A nrPDB 101 5e-22 2O2S-A nrPDB 101 5e-22 1B15-A nrPDB 99 2e-21 4HWK-A nrPDB 93 2e-19 4Z3K-A nrPDB 92 2e-19 2PTG-A nrPDB 92 2e-19 1MG5-A nrPDB 91 3e-19 3U9L-A nrPDB 91 5e-19 5LCX-A nrPDB 88 4e-18 1OAA-A nrPDB 88 5e-18 4OYR-A nrPDB 82 2e-16 3F4B-A nrPDB 80 7e-16 5TQV-A nrPDB 79 1e-15 5WQO-A nrPDB 78 4e-15 2NTV-A nrPDB 77 1e-14 2O2Y-A nrPDB 68 5e-12 3SLK-A nrPDB 67 9e-12 2PK3-A nrPDB 54 6e-08 3ORF-A nrPDB 51 5e-07 4LIS-A nrPDB 50 8e-07 1OOE-A nrPDB 48 3e-06 6BWL-A nrPDB 47 7e-06 1Z45-A nrPDB 47 8e-06 1UDA-A nrPDB 45 3e-05 3RFT-A nrPDB 44 6e-05 1I3M-A nrPDB 43 1e-04 3ENK-A nrPDB 43 1e-04 1DIR-A nrPDB 42 2e-04 2Q1W-A nrPDB 41 6e-04 4R1T-A nrPDB 41 7e-04 1ZZE-A nrPDB 39 0.002 3SXP-A nrPDB 39 0.002 1KEU-A nrPDB 39 0.002 2GN9-A nrPDB 39 0.003 6GCS-E nrPDB 39 0.003 2NNL-D nrPDB 38 0.004 1VL0-A nrPDB 38 0.005 1BXK-A nrPDB 38 0.005 6DEB-A nrPDB 37 0.006 4PVC-A nrPDB 37 0.006 1GY8-A nrPDB 37 0.007 4G5H-A nrPDB 37 0.008 6ACF-A nrPDB 37 0.010 2PZM-A nrPDB 37 0.010 5N2I-A nrPDB 36 0.013 5K1S-A nrPDB 36 0.015 4KUG-A nrPDB 36 0.016 4A10-A nrPDB 36 0.016 2C20-A nrPDB 36 0.022 1LU9-A nrPDB 35 0.031 1OC2-A nrPDB 35 0.042 4QUK-A nrPDB 34 0.047 2HUN-A nrPDB 34 0.047 4K28-A nrPDB 34 0.055 6G2J-P nrPDB 34 0.056 6ACQ-A nrPDB 34 0.064 5F5N-A nrPDB 34 0.072 3OND-A nrPDB 34 0.074 5AOV-A nrPDB 34 0.083 3PEF-A nrPDB 33 0.11 3CT4-A nrPDB 33 0.12 5B6K-A nrPDB 33 0.12 2P4H-X nrPDB 33 0.12 3VPX-A nrPDB 33 0.13 5GUP-L nrPDB 33 0.13 2Z95-A nrPDB 33 0.14 3N58-A nrPDB 33 0.14 3HZZ-A nrPDB 33 0.16 4EUF-A nrPDB 32 0.17 4R1U-A nrPDB 32 0.17 3NJ4-A nrPDB 32 0.17 1O89-A nrPDB 32 0.18 4J2O-A nrPDB 32 0.19 3LK7-A nrPDB 32 0.19 3SC6-A nrPDB 32 0.22 4B3J-A nrPDB 32 0.22 3X2F-A nrPDB 32 0.24 1R66-A nrPDB 32 0.27 6GBN-A nrPDB 32 0.28 5JXW-A nrPDB 32 0.29 6BII-A nrPDB 32 0.30 3PVZ-A nrPDB 32 0.30 1DB3-A nrPDB 32 0.31 2EXX-A nrPDB 32 0.36 3S8M-A nrPDB 31 0.41 2EER-A nrPDB 31 0.46 4BKP-A nrPDB 31 0.46 4J6F-A nrPDB 31 0.47 5OCM-A nrPDB 31 0.47 4WLE-A nrPDB 31 0.48 5UZH-A nrPDB 31 0.51 3H6N-A nrPDB 31 0.51 1RPN-A nrPDB 31 0.52 3DC2-A nrPDB 31 0.54 5TEN-A nrPDB 31 0.55 4PZE-A nrPDB 31 0.64 2HK7-A nrPDB 31 0.73 5V6R-A nrPDB 31 0.76 1XDW-A nrPDB 30 0.93 1EDZ-A nrPDB 30 0.94 1ZDL-A nrPDB 30 0.99 2DFV-A nrPDB 30 1.0 4E0B-A nrPDB 30 1.1 4KTT-E nrPDB 30 1.2 4J0E-A nrPDB 30 1.2 4KDR-A nrPDB 30 1.2 1K20-A nrPDB 30 1.3 1JAY-A nrPDB 30 1.3 4YZP-A nrPDB 30 1.3 4UUP-A nrPDB 30 1.3 4KDC-A nrPDB 30 1.4 6APE-A nrPDB 29 1.6 1ZCJ-A nrPDB 29 1.6 4B4V-A nrPDB 29 1.7 3QFF-A nrPDB 29 1.7 4WOK-A nrPDB 29 1.7 1JPH-A nrPDB 29 1.8 2C54-A nrPDB 29 1.8 4D3S-A nrPDB 29 1.9 3A31-A nrPDB 29 1.9 3ZWA-A nrPDB 29 2.2 5KIA-A nrPDB 29 2.3 6HRD-A nrPDB 29 2.3 4XGU-A nrPDB 29 2.4 1F14-A nrPDB 29 2.4 6H0D-A nrPDB 29 2.5 5GXF-A nrPDB 29 2.7 4B4O-A nrPDB 29 2.7 4J90-A nrPDB 29 2.8 2Q4B-A nrPDB 29 2.8 3R9I-A nrPDB 29 3.1 6C6P-A nrPDB 28 3.6 6GAR-A nrPDB 28 4.0 4A5O-A nrPDB 28 4.0 2YQ5-A nrPDB 28 4.2 4B3F-X nrPDB 28 4.3 1YXY-A nrPDB 28 4.4 2OHJ-A nrPDB 28 4.6 4GBJ-A nrPDB 28 4.6 1IE3-A nrPDB 28 4.6 4MIE-A nrPDB 28 4.6 3HDH-A nrPDB 28 4.7 3L9K-A nrPDB 28 4.7 3DMF-A nrPDB 28 5.4 5NUE-A nrPDB 27 5.4 3K4W-A nrPDB 27 5.6 1MLD-A nrPDB 27 5.8 2BC1-A nrPDB 27 6.1 4EJ0-A nrPDB 27 6.3 4Z6K-A nrPDB 27 6.4 3D64-A nrPDB 27 6.7 6BMQ-A nrPDB 27 6.8 5BUT-A nrPDB 27 6.8 3K6J-A nrPDB 27 6.8 2HMT-A nrPDB 27 7.3 4WEQ-A nrPDB 27 7.7 1PGJ-A nrPDB 27 9.1 6CAU-A nrPDB 27 9.6 3L07-A nrPDB 27 9.8 >4CQL-A nrPDB Length = 261 Score = 329 bits (844), Expect = 8e-91, Method: Composition-based stats. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS Sbjct: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW Sbjct: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT Sbjct: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL Sbjct: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 ASEDSGYITGTSVEVTGGLFM Sbjct: 241 ASEDSGYITGTSVEVTGGLFM 261 >2PNF-A nrPDB Length = 248 Score = 290 bits (743), Expect = 4e-79, Method: Composition-based stats. Identities = 96/256 (37%), Positives = 147/256 (57%), Gaps = 8/256 (3%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 ++ +L+ ++LVTG+ GIGRA++ +LA G+TV A+ + Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANK------ 54 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 + ++ + E++ ++V+ AGIT+D+ L MS DW++V+ Sbjct: 55 YGVKAHGVEMNLLSEESINKAFEEIYNLVDGI-DILVNNAGITRDKLFLRMSLLDWEEVL 113 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 VNL GTFLVTQ + + ++ G I+NISS+VG GNVGQ NY+ +KAG+IG T++ A Sbjct: 114 KVNLTGTFLVTQNSLRKMIKQRW-GRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLA 172 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASED 244 +EL + N+V PGFI T MT + +++ K E IP+G G PE+VA+VV FL SE Sbjct: 173 KELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSEL 232 Query: 245 SGYITGTSVEVTGGLF 260 + YITG + V GG+F Sbjct: 233 ASYITGEVIHVNGGMF 248 >4JRO-A nrPDB Length = 271 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 112/254 (44%), Positives = 156/254 (61%), Gaps = 10/254 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPRG 67 L+ +A+VTG GIGR +++ LA EGA + AA+ET +L+ G + Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVE------ 80 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A +A+V+ A +Q F R ++V+ AGIT+D L+ M ED+WD VI +N Sbjct: 81 -VEAMKANVAIAEDVDAFFKQAIERFGR-VDILVNNAGITRDNLLMRMKEDEWDDVININ 138 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKGTFL T+A ++ ++ G IIN++S+VG +GN GQ NY ASKAGVIGLT+T AREL Sbjct: 139 LKGTFLCTKAVSRTMMKQ-RAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTAREL 197 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 GI N+V PGFI T MT K+ +K + + IP+G G ED+A+ V FLAS+ S Y Sbjct: 198 APRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKY 257 Query: 248 ITGTSVEVTGGLFM 261 ITG ++ V GG+ M Sbjct: 258 ITGQTLSVDGGMVM 271 >2UVD-A nrPDB Length = 246 Score = 286 bits (733), Expect = 6e-78, Method: Composition-based stats. Identities = 103/254 (40%), Positives = 155/254 (61%), Gaps = 10/254 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPRG 67 L+ +ALVTGA GIGRA+++ LA +GA V + A E V + GS Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGS------- 54 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + A +ADV+ A +++Q F + ++V+ AG+T+D L+ M E++WD VI N Sbjct: 55 DAIAVRADVANAEDVTNMVKQTVDVFGQ-VDILVNNAGVTKDNLLMRMKEEEWDTVINTN 113 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG FL T+A ++ ++ G I+NI+S+VG GN GQ NY A+KAGVIGLT+T+A+EL Sbjct: 114 LKGVFLCTKAVSRFMMRQ-RHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKEL 172 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 I N++ PGFIAT MT + + + ++ ++IP G+ +D+A+ V F AS+ S Y Sbjct: 173 ASRNITVNAIAPGFIATDMTDVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKY 232 Query: 248 ITGTSVEVTGGLFM 261 ITG ++ V GG+ M Sbjct: 233 ITGQTLNVDGGMVM 246 >3OSU-A nrPDB Length = 246 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 105/251 (41%), Positives = 153/251 (60%), Gaps = 10/251 (3%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPRGNHA 70 ALVTGA GIGR+++++LA EG VA + A+ V + G + Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGV-------DSF 57 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 A QA+V++A + ++++V + F V+V+ AGIT+D L+ M E +WD VI NLKG Sbjct: 58 AIQANVADADEVKAMIKEVVSQFGSL-DVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKG 116 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F Q A ++ G+IIN+SS+VG VGN GQ NY A+KAGVIGLT++AAREL Sbjct: 117 VFNCIQKATPQMLRQ-RSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASR 175 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 GI N+V PGFI + MT + ++ +++ IP+ G D+A+ VAFLAS+ + YITG Sbjct: 176 GITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITG 235 Query: 251 TSVEVTGGLFM 261 ++ V GG++M Sbjct: 236 QTIHVNGGMYM 246 >2HQ1-A nrPDB Length = 247 Score = 282 bits (723), Expect = 9e-77, Method: Composition-based stats. Identities = 99/254 (38%), Positives = 142/254 (55%), Gaps = 8/254 (3%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L+ A+VTG+ G+G+A++ +L GA + + L + Sbjct: 2 QLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPAST------SLDATAEEFKAAGI 55 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 N + DV +++ F R ++V+ AGIT+D +L MSE DWD V+ N Sbjct: 56 NVVVAKGDVKNPEDVENMVKTAMDAFGRI-DILVNNAGITRDTLMLKMSEKDWDDVLNTN 114 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LK +L T+A ++ ++ G IINI+SI G +GN GQ NYAASKAG+IG T++ A+E Sbjct: 115 LKSAYLCTKAVSKIMLKQ-KSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEF 173 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 GI CN+V PG I T MT +P KV + IP+ G PE+VA+VV FLAS+DS Y Sbjct: 174 AAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 248 ITGTSVEVTGGLFM 261 ITG + + GGL M Sbjct: 234 ITGQVINIDGGLVM 247 >2C07-A nrPDB Length = 285 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 93/250 (37%), Positives = 141/250 (56%), Gaps = 9/250 (3%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + +ALVTGAG GIGR ++ LA + V + + V + G + Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESS------ 96 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 + DVS+ ++ ++ + ++V+ AGIT+D L M D+W+ V+ NL Sbjct: 97 -GYAGDVSKKEEISEVINKILTE-HKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLN 154 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGR 189 F +TQ ++ ++ N G IINISSIVG GNVGQ NY++SKAGVIG T++ A+EL Sbjct: 155 SLFYITQPISKRMI-NNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELAS 213 Query: 190 HGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249 I N++ PGFI++ MT K+ +++ I IP G +G PE+VA++ FL+S+ SGYI Sbjct: 214 RNITVNAIAPGFISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYIN 273 Query: 250 GTSVEVTGGL 259 G + GGL Sbjct: 274 GRVFVIDGGL 283 >3RSH-A nrPDB Length = 251 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 97/259 (37%), Positives = 144/259 (55%), Gaps = 13/259 (5%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 SQ N L +ALVTGA GIG+A++ LA GA V + AQ LG G Sbjct: 5 SQFMN-LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK-- 61 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 +V+ + +L+ + F ++V+ AGIT+D L+ M E++W Sbjct: 62 --------GMALNVTNPESIEAVLKAITDEFGG-VDILVNNAGITRDNLLMRMKEEEWSD 112 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 ++ NL F +++A + ++ G IIN+ S+VG +GN GQ NYAA+KAGVIG T++ Sbjct: 113 IMETNLTSIFRLSKAVLRGMMKKRQ-GRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKS 171 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 ARE+ G+ N+V PGFI T MT+ + + +P G LGDP ++A VAFLAS Sbjct: 172 MAREVASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVPAGRLGDPREIASAVAFLAS 231 Query: 243 EDSGYITGTSVEVTGGLFM 261 ++ YITG ++ V GG++M Sbjct: 232 PEAAYITGETLHVNGGMYM 250 >3FTP-A nrPDB Length = 270 Score = 273 bits (698), Expect = 6e-74, Method: Composition-based stats. Identities = 109/257 (42%), Positives = 151/257 (58%), Gaps = 9/257 (3%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + L +A+VTGA GIGRA+++ LA GA V A A+ G G+ Sbjct: 22 MDKTLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAE-------GIGAAFKQ 74 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 +V++A A L+E F +V+V+ AGITQD+ + M +D+WD VI Sbjct: 75 AGLEGRGAVLNVNDATAVDALVESTLKEFGAL-NVLVNNAGITQDQLAMRMKDDEWDAVI 133 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 NLK F +++A + ++ G I+NI+S+VG GN GQ NYAA+KAGV G+T+ A Sbjct: 134 DTNLKAVFRLSRAVLRPMMKA-RGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALA 192 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASED 244 RE+G GI N V PGFI T MT+ +PQ+ + IP+G LG PED+A VAFLAS Sbjct: 193 REIGSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQ 252 Query: 245 SGYITGTSVEVTGGLFM 261 +GYITGT++ V GG+FM Sbjct: 253 AGYITGTTLHVNGGMFM 269 >3LYL-A nrPDB Length = 247 Score = 272 bits (697), Expect = 9e-74, Method: Composition-based stats. Identities = 97/253 (38%), Positives = 146/253 (57%), Gaps = 9/253 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L +ALVTGA GIG V+ LA +GATV +A+A++ + G K Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKAR----- 57 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 ++S+ + + +++A + ++V+ AGIT+D ++ MSED+W VI NL Sbjct: 58 --GLVLNISDIESIQNFFAEIKAE-NLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNL 114 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F +++ + ++ G II+I S+VG GN GQTNY A+KAGVIG +++ A E+ Sbjct: 115 SSIFRMSKECVRGMMKKRW-GRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVA 173 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 I N V PGFIAT MT K+ + I IP G +G+P+D+A VAFLASE++ YI Sbjct: 174 SRNITVNVVAPGFIATDMTDKLTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYI 233 Query: 249 TGTSVEVTGGLFM 261 TG ++ V GG++M Sbjct: 234 TGQTLHVNGGMYM 246 >1Q7C-A nrPDB Length = 244 Score = 268 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 94/254 (37%), Positives = 144/254 (56%), Gaps = 12/254 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +ALVTGA GIGRA++ LA GA V AQ LG G Sbjct: 2 NFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGK------- 54 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 +V++ + +LE+++A F ++V+ AGIT+D L+ M +++W+ +I N Sbjct: 55 ---GLMLNVTDPASIESVLEKIRAEFGE-VDILVNNAGITRDNLLMRMKDEEWNDIIETN 110 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L F +++A +A++ G II I S+VG +GN GQ N+AA+KAG+IG +++ ARE+ Sbjct: 111 LSSVFRLSKAVMRAMMKK-RHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREV 169 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 GI N V PGFI T MT+ + I +P G LG +++A+ VAFLAS+++ Y Sbjct: 170 ASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAY 229 Query: 248 ITGTSVEVTGGLFM 261 ITG ++ V GG++M Sbjct: 230 ITGETLHVNGGMYM 243 >3EMK-A nrPDB Length = 246 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 91/253 (35%), Positives = 137/253 (54%), Gaps = 12/253 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L ALVTGA G+G A++ L +GA V +E LG Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGE----------R 54 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 F A++S+ A + L ++ + ++V+ AGIT+D + MS++DWD V+ VNL Sbjct: 55 IFVFPANLSDREAVKALGQKAEEEMGG-VDILVNNAGITRDGLFVRMSDEDWDAVLTVNL 113 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F +T+ ++ G IINI+SIVG GN GQ NY ASKAG+IG +++ A+E+ Sbjct: 114 TSVFNLTRELTHPMMRR-RNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIA 172 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 + N + PGFI + MT K+ +K D I IPM +G D+A V +LAS+++ Y+ Sbjct: 173 SRNVTVNCIAPGFIESAMTGKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYV 232 Query: 249 TGTSVEVTGGLFM 261 TG ++ V GG+ M Sbjct: 233 TGQTLHVNGGMAM 245 >5CDY-A nrPDB Length = 244 Score = 267 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 93/253 (36%), Positives = 138/253 (54%), Gaps = 12/253 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 +ALVTGA GIGRA++ L GA V A+ LG G Sbjct: 3 FEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGK-------- 54 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 +V + + +L ++A F ++V+ AGIT+D L+ M +D+W +I NL Sbjct: 55 --GLMLNVVDPTSIDTVLATIRAEFGE-VDILVNNAGITRDNLLMRMKDDEWQDIIDTNL 111 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F +++A +A++ G II I S+VG +GN GQ NYAA+KAGVIG +++ ARE+ Sbjct: 112 TSVFRLSKAVMRAMMKK-RFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVA 170 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 GI N V PGFI T MT+ + I +P LGD +++A VAFLAS+++ YI Sbjct: 171 SRGITVNVVAPGFIETDMTRTLTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYI 230 Query: 249 TGTSVEVTGGLFM 261 +G ++ V GG++M Sbjct: 231 SGETLHVNGGMYM 243 >4M8S-A nrPDB Length = 248 Score = 265 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 97/256 (37%), Positives = 143/256 (55%), Gaps = 11/256 (4%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 L +ALVTGA GIG A++ LA GA V + A L G + Sbjct: 3 TQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGE---- 58 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + +E L+ ++ F + ++V+ AGIT+D L+ M E++WD ++ Sbjct: 59 -----GRVLNSAEPETVENLIADIEKTFGKL-DILVNNAGITRDNLLMRMKEEEWDDIMQ 112 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VNLK F ++A + ++ G IINI+S+VG +GN GQTNYAA+KAG+IG +++ AR Sbjct: 113 VNLKSVFRASKAVLRGMMKQ-RAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAR 171 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 E+G GI N V PGFI T MT+ +P++ T +G GD +D+AD V FLAS+ + Sbjct: 172 EVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQA 231 Query: 246 GYITGTSVEVTGGLFM 261 YITG ++ V GG+ M Sbjct: 232 KYITGQTLHVNGGMLM 247 >4BO1-A nrPDB Length = 269 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 99/253 (39%), Positives = 147/253 (58%), Gaps = 9/253 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +ALVTGA GIG+A+++ L GA V + A++ L G + Sbjct: 25 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEG------ 78 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A DVS + LE +Q +P +VV+ AGIT+D L+ M +D+W V+ NL Sbjct: 79 -AGLVLDVSSDESVAATLEHIQQHLGQPL-IVVNNAGITRDNLLVRMKDDEWFDVVNTNL 136 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 + +++A + + G IINI S+VG +GN GQTNYAA+KAG+ G T+ ARE+G Sbjct: 137 NSLYRLSKAVLRGMTKARW-GRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVG 195 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 I N+V PGFI T MT+++P+ + + IP+G LG E++A VV FLAS+ + Y+ Sbjct: 196 SRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYV 255 Query: 249 TGTSVEVTGGLFM 261 TG +V V GG++M Sbjct: 256 TGATVPVNGGMYM 268 >3WOH-A nrPDB Length = 251 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 104/254 (40%), Positives = 151/254 (59%), Gaps = 12/254 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPRG 67 L +ALVTG G+GRA+++RLA +GA VA + D ++A+ET + G G Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLG-------G 61 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 +++ DVS+A ++ V A P ++V+ AGI +D + ++D+D V+ N Sbjct: 62 TARSYRCDVSDAEQVTRCVKAVTADLG-PVDILVNNAGIIRDGLAASIKDEDYDAVMNTN 120 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG FL +A + GSIINISS+ G G+ GQ NYA++KAG+IGLT++ A+EL Sbjct: 121 LKGAFLFIKACYFGFIRK-RSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKEL 179 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 +RCN+V PG IAT MTQ + K + +PM G P++VA +VAFLA ++S Y Sbjct: 180 AERNVRCNAVAPGLIATDMTQDLVDD--SKRLDPVPMRRFGRPDEVAGLVAFLAGDESSY 237 Query: 248 ITGTSVEVTGGLFM 261 ITG V V GG+ M Sbjct: 238 ITGQVVCVDGGMAM 251 >3F9I-A nrPDB Length = 249 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 94/256 (36%), Positives = 137/256 (53%), Gaps = 16/256 (6%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 L +L+TGA SGIG A++ L G+ V + + L Sbjct: 9 MIDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKD-------- 60 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 N+ +++ L+ + ++V AGIT D + M + D+DKVI Sbjct: 61 --NYTIEVCNLANKEECSNLISKTSN-----LDILVCNAGITSDTLAIRMKDQDFDKVID 113 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 +NLK F++ + A + ++ G IINISSIVG GN GQ NY ASKAG+IG+T++ + Sbjct: 114 INLKANFILNREAIKKMIQKRY-GRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSY 172 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 E+ GI N+V PGFI + MT K+ +K + I + IP+G G PEDVA VAFLAS ++ Sbjct: 173 EVATRGITVNAVAPGFIKSDMTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNA 232 Query: 246 GYITGTSVEVTGGLFM 261 YITG ++ V GG+ M Sbjct: 233 SYITGQTLHVNGGMLM 248 >4DMM-A nrPDB Length = 269 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 112/261 (42%), Positives = 153/261 (58%), Gaps = 13/261 (4%) Query: 3 SQLQN-RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSK 61 S + L +ALVTGA GIGRA+++ LA GA VA A A + Sbjct: 19 SHMTALPLTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAA------DEVVAA 72 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWD 121 G A +ADVS+ L V + R V+V+ AGIT+D LL M DDW Sbjct: 73 IAAAGGEAFAVKADVSQESEVEALFAAVIERWGRL-DVLVNNAGITRDTLLLRMKRDDWQ 131 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 V+ +NL G FL ++AAA+ ++ G IINI+S+VG++GN GQ NY+A+KAGVIGLT+ Sbjct: 132 SVLDLNLGGVFLCSRAAAKIMLKQ-RSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTK 190 Query: 182 TAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 T A+EL GI N+V PGFIAT MT ++ +K+ E+IP+G G+ +VA VV FLA Sbjct: 191 TVAKELASRGITVNAVAPGFIATDMTSEL---AAEKLLEVIPLGRYGEAAEVAGVVRFLA 247 Query: 242 SE-DSGYITGTSVEVTGGLFM 261 ++ + YITG + + GGL M Sbjct: 248 ADPAAAYITGQVINIDGGLVM 268 >2PH3-A nrPDB Length = 245 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 100/248 (40%), Positives = 142/248 (57%), Gaps = 7/248 (2%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 AL+TGA GIGRA+++RLA +G +A Q + A Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHY-----GQNREKAEEVAEEARRRGSPLVAV 56 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 A++ EA AA L+ Q +V+ AGIT+D L+ M ++DW+ V+ NL Sbjct: 57 LGANLLEAEAATALVHQAAEVLGGL-DTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAV 115 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHG 191 F T+ A + ++ G I+NI+S+VG +GN GQ NY ASKAG+IG T+ A+E + G Sbjct: 116 FRTTREAVKLMMKA-RFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRG 174 Query: 192 IRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGT 251 I N+V PGFI T MT+++PQ+V + + IP G G PE+VA+ VAFL SE +GYITG Sbjct: 175 ITVNAVAPGFIETEMTERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQ 234 Query: 252 SVEVTGGL 259 ++ V GGL Sbjct: 235 TLCVDGGL 242 >3GRP-A nrPDB Length = 266 Score = 259 bits (663), Expect = 8e-70, Method: Composition-based stats. Identities = 90/254 (35%), Positives = 139/254 (54%), Gaps = 12/254 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L ALVTGA GIG A++ +GA V +E LG Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGK---------- 73 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + F A++S+ ++ + L E + ++V+ AGIT+D + M + DWD V+AVN Sbjct: 74 DVFVFSANLSDRKSIKQLAEVAEREMEGI-DILVNNAGITRDGLFVRMQDQDWDDVLAVN 132 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L +T+ +++ G IINI+SIVG VGN GQTNY A+KAG+IG ++ A+E+ Sbjct: 133 LTAASTLTRELIHSMMRRRY-GRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEI 191 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 I N + PGFI + MT K+ +K + I MIPM +G E++A +LAS+++ Y Sbjct: 192 ASRNITVNCIAPGFIKSAMTDKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAY 251 Query: 248 ITGTSVEVTGGLFM 261 +TG ++ + GG+ M Sbjct: 252 LTGQTLHINGGMAM 265 >4NBT-A nrPDB Length = 240 Score = 258 bits (660), Expect = 1e-69, Method: Composition-based stats. Identities = 97/258 (37%), Positives = 144/258 (55%), Gaps = 20/258 (7%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 +L +A++TG G+G+A+++ A EGA V A DL Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD----------------LTYS 44 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 N +V++ + V + + ++V+ AGIT+D M+E WD VI Sbjct: 45 HPNVEGMYLNVTDVTGVEKFYQSVIDKYGKI-DILVNNAGITKDAMTRKMTEAQWDAVID 103 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VNLKG F +T+ + +NG GSIINISS+VG GN+GQ NYAA+KAGVIGLT T A+ Sbjct: 104 VNLKGVFNLTRLVGPQMQTNGY-GSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAK 162 Query: 186 ELGRHG--IRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 E G +R N++ PG+I T + + VPQ ++DK + + LG PE++A V FLAS+ Sbjct: 163 EFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASD 222 Query: 244 DSGYITGTSVEVTGGLFM 261 D+ Y+TG ++ V GG+ + Sbjct: 223 DASYVTGQTINVNGGMRL 240 >4KMS-A nrPDB Length = 249 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 95/251 (37%), Positives = 143/251 (56%), Gaps = 12/251 (4%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +A+VTG GIG+A ++ L +G TV A A + + G +K Sbjct: 10 SEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCW------- 62 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 +V++ R +++++ F +P S++V+ AGIT+D+ L MS DW+ VI VNL Sbjct: 63 ----NVADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNS 118 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F ++ + + + + G I+NISSI + G VGQTNY+A+KAG+IG T+ ARE Sbjct: 119 CFNMSSSVMEQMRNQDY-GRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASK 177 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 I N + PG+IAT M VP+ V+ KI IP LG PE++A VAFL E++G+ITG Sbjct: 178 NITVNCIAPGYIATEMVGAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITG 237 Query: 251 TSVEVTGGLFM 261 ++ + GG M Sbjct: 238 ETISINGGHNM 248 >4NBV-A nrPDB Length = 246 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 104/254 (40%), Positives = 152/254 (59%), Gaps = 9/254 (3%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L+ +A++TGA +GIG A + R A +GA V CD+ A +E ++ Sbjct: 2 KLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAA-------ARLAATGA 54 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 +A++ DV+ ++ V A R ++V+ AGIT+D L M+E +D VI VN Sbjct: 55 TVSAYRVDVTRRDEVDAMVAAVLAAHQR-VDILVNNAGITKDARLAKMTEAQFDAVIDVN 113 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG F QA A + G +G I+N SS+VG GN GQTNYAASK GVIG T+T AREL Sbjct: 114 LKGVFNCAQAVAGLMTEQG-KGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWAREL 172 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 G G+R N+V PGF+ T + Q VP KV+D +T + L +P ++A + AFLAS+D+ Y Sbjct: 173 GPKGVRVNAVCPGFVNTEILQTVPDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASY 232 Query: 248 ITGTSVEVTGGLFM 261 + G ++E +GG+ + Sbjct: 233 VNGVAIEASGGMSL 246 >1GEE-A nrPDB Length = 261 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 80/260 (30%), Positives = 136/260 (52%), Gaps = 11/260 (4%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD-RAAAQETVRLLGGPGSKEG 63 + L + ++TG+ +G+G+++++R A E A V A + + G Sbjct: 1 MYKDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVG---- 56 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 G A + DV+ L++ F + V+++ AG+ MS DW+KV Sbjct: 57 ---GEAIAVKGDVTVESDVINLVQSAIKEFGKL-DVMINNAGLENPVSSHEMSLSDWNKV 112 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 I NL G FL ++ A + V N +G++IN+SS+ K+ +YAASK G+ +T+T Sbjct: 113 IDTNLTGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETL 172 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQK--VPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A E GIR N++ PG I TP+ + + + MIPMG++G+PE++A V A+LA Sbjct: 173 ALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLA 232 Query: 242 SEDSGYITGTSVEVTGGLFM 261 S ++ Y+TG ++ GG+ + Sbjct: 233 SSEASYVTGITLFADGGMTL 252 >3OEC-A nrPDB Length = 317 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 91/277 (32%), Positives = 145/277 (52%), Gaps = 25/277 (9%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAA-----AQETVRLLGGPGS 60 NRL+ +A +TGA G GR +VRLA +GA + A DL R AQ + L Sbjct: 41 MNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVR 100 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 A QADV + + + ++++ A F ++VS GI+ ++ +++ W Sbjct: 101 LVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHI-DILVSNVGISNQGEVVSLTDQQW 159 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 ++ NL G + +A +++ G GS+I +SS VG G GQ++YAASK GV GL Sbjct: 160 SDILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLM 219 Query: 181 QTAARELGRHGIRCNSVLPGFIATPM-----------------TQKVPQKVVDKITEMIP 223 + A E+GRH IR NSV PG + T M T++ ++ ++T ++P Sbjct: 220 LSLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLT-LLP 278 Query: 224 MGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLF 260 + +PEDV++ VA+LAS+++ YI G ++ V GG Sbjct: 279 IP-WVEPEDVSNAVAWLASDEARYIHGAAIPVDGGQL 314 >2CDH-G nrPDB Length = 244 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 103/250 (41%), Positives = 143/250 (57%), Gaps = 9/250 (3%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S + +VTGA GIG+A+++ L G V A A E V + G Sbjct: 1 SPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSK------QIEAYGGQAI 54 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 F DVS+ +++ + VVV+ AGIT+D L+ M + WD+VI +NL G Sbjct: 55 TFGGDVSKEADVEAMMKTAIDAWGTI-DVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTG 113 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 FL TQAA + ++ +G IINI+S+VG +GN+GQ NYAA+KAGVIG ++TAARE Sbjct: 114 VFLCTQAATKIMMKK-RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASR 172 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA-SEDSGYIT 249 I N V PGFIA+ MT K+ + + KI IP+G G PE+VA +V FLA S + YIT Sbjct: 173 NINVNVVCPGFIASDMTAKLGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYIT 232 Query: 250 GTSVEVTGGL 259 G + + GG+ Sbjct: 233 GQAFTIDGGI 242 >4K6F-A nrPDB Length = 255 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 96/263 (36%), Positives = 150/263 (57%), Gaps = 11/263 (4%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACD-LDRAAAQETVRLLGGPG 59 MA + + +A+VTG G+G AVS+RL G V + A + + G Sbjct: 1 MAHHHHHHMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAG 60 Query: 60 SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD 119 + A+ DV++ + + +E++ P ++V+ AGIT+D L + + + Sbjct: 61 RE-------FHAYPVDVADHDSCQQCIEKIVRDVG-PVDILVNNAGITRDMTLRKLDKVN 112 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 WD VI NL F +T+ +V G G I+NISS+ G G+VGQTNYAA+KAG+ G Sbjct: 113 WDAVIRTNLDSVFNMTKPVCDGMVERGW-GRIVNISSVNGSKGSVGQTNYAAAKAGMHGF 171 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVD-KITEMIPMGHLGDPEDVADVVA 238 T++ A E+ R G+ N+V PG++AT M +PQ ++D KI IP G LG PE+VA +VA Sbjct: 172 TKSLALEIARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVA 231 Query: 239 FLASEDSGYITGTSVEVTGGLFM 261 +L SE++G++TG+++ + GG M Sbjct: 232 YLCSEEAGFVTGSNIAINGGQHM 254 >3AUT-A nrPDB Length = 269 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 81/258 (31%), Positives = 132/258 (51%), Gaps = 11/258 (4%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD-RAAAQETVRLLGGPGSKEG 63 + L+ + ++TG +G+GRA++VR E A V + A + + + G Sbjct: 9 MYTDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAG---- 64 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 G Q DV++ L++ F V+++ AG+ +S D+W+KV Sbjct: 65 ---GQAIIVQGDVTKEEDVVNLVQTAIKEFGTL-DVMINNAGVENPVPSHELSLDNWNKV 120 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 I NL G FL ++ A + V N +G++IN+SS+ + +YAASK G+ +T+T Sbjct: 121 IDTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETL 180 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQK--VPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A E GIR N++ PG + TP+ + + MIPMG++G PE+VA V AFLA Sbjct: 181 ALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLA 240 Query: 242 SEDSGYITGTSVEVTGGL 259 S + Y+TG ++ GG+ Sbjct: 241 SSQASYVTGITLFADGGM 258 >5ITV-A nrPDB Length = 255 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 83/263 (31%), Positives = 132/263 (50%), Gaps = 19/263 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + L L+TG SGIG A G+ A V D+D A + VR Sbjct: 1 MIMNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRK---------E 51 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 Q D+++ A + +E F V+++ AGI + M DW+KV+ Sbjct: 52 NNDRLHFVQTDITDEAACQHAVESAVHTFGGL-DVLINNAGIEIVAPIHEMELSDWNKVL 110 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 VNL G FL+++ A + +++ G +G+IIN S+ G V Y ASK GV+ LT++ A Sbjct: 111 QVNLTGMFLMSKHALKHMLAAG-KGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA 169 Query: 185 RELGRHGIRCNSVLPGFIATPMTQK--------VPQKVVDKITEMIPMGHLGDPEDVADV 236 + +H IR N V PG I TP+ +K +++ + ++ P+ LG PE++A+V Sbjct: 170 VDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANV 229 Query: 237 VAFLASEDSGYITGTSVEVTGGL 259 + FLAS+ S Y+TG+++ GG Sbjct: 230 MLFLASDLSSYMTGSAITADGGY 252 >2NM0-A nrPDB Length = 253 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 90/251 (35%), Positives = 135/251 (53%), Gaps = 20/251 (7%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S LVTG GIG A++ A G VA G P Sbjct: 21 SRSVLVTGGNRGIGLAIARAFADAGDKVAITYRS------------------GEPPEGFL 62 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 A + D+++ ++++ P V+++ AG+T+D+ L+ MSE+D+ V+ NL G Sbjct: 63 AVKCDITDTEQVEQAYKEIEETHG-PVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTG 121 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 TF V + A +A++ +G ++ ISS+VG +G+ GQ NYAASKAG++G ++ ARELG Sbjct: 122 TFRVVKRANRAML-RAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSR 180 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 I N V PGF+ T MT+ + + I +P+G PE++A V FLAS+D+ YITG Sbjct: 181 NITFNVVAPGFVDTDMTKVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITG 240 Query: 251 TSVEVTGGLFM 261 + V GGL M Sbjct: 241 AVIPVDGGLGM 251 >4RZH-A nrPDB Length = 247 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 103/257 (40%), Positives = 147/257 (57%), Gaps = 12/257 (4%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 L + +ALVTGA GIG+A ++ LA G V + A + V ++ Sbjct: 1 MTALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVV------AEIIAN 54 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 G A QA+V+ A L++ FSR V+V+ AGIT+D LL M +DW VI Sbjct: 55 GGEAIAVQANVANADEVDQLIKTTLDKFSRI-DVLVNNAGITRDTLLLRMKLEDWQAVID 113 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 +NL G FL T+A ++ ++ G IINI+S+ G +GN GQ NY+A+KAGVIG T+T A+ Sbjct: 114 LNLTGVFLCTKAVSKLMLKQ-KSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAK 172 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE-D 244 EL G+ N+V PGFIAT MT+ + + I + IP+ G PE+VA + FLA++ Sbjct: 173 ELASRGVTVNAVAPGFIATDMTENLN---AEPILQFIPLARYGQPEEVAGTIRFLATDPA 229 Query: 245 SGYITGTSVEVTGGLFM 261 + YITG + V GG+ M Sbjct: 230 AAYITGQTFNVDGGMVM 246 >3EZL-A nrPDB Length = 256 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 88/254 (34%), Positives = 136/254 (53%), Gaps = 10/254 (3%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAA-CDLDRAAAQETVRLLGGPGSKEGPPRG 67 + +A VTG GIG ++ RL +G V A C + + + G Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGF------- 63 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + A + +V + + + ++V+A V+V+ AGIT+D M+ +DW VI N Sbjct: 64 DFYASEGNVGDWDSTKQAFDKVKAEVGEI-DVLVNNAGITRDVVFRKMTREDWQAVIDTN 122 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L F VT+ +V G G IINISS+ G+ G GQTNY+ +KAG+ G T + A+E+ Sbjct: 123 LTSLFNVTKQVIDGMVERGW-GRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEV 181 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 G+ N+V PG+I T M + + V++KI IP+ LG P+++ +VA+LASE+SG+ Sbjct: 182 ATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGF 241 Query: 248 ITGTSVEVTGGLFM 261 TG + GGL M Sbjct: 242 STGADFSLNGGLHM 255 >1GEG-A nrPDB Length = 256 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 93/260 (35%), Positives = 136/260 (52%), Gaps = 19/260 (7%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +ALVTGAG GIG+A+++RL +G VA D + A A+ + G G+ A Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAG-------GHAVA 55 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 + DVS+ +EQ + V+V+ AG+ + ++ + DKV +N+KG Sbjct: 56 VKVDVSDRDQVFAAVEQARKTLGGF-DVIVNNAGVAPSTPIESITPEIVDKVYNINVKGV 114 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHG 191 QAA +A G G IIN S G VGN Y++SK V GLTQTAAR+L G Sbjct: 115 IWGIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLG 174 Query: 192 IRCNSVLPGFIATPMTQKVPQKVVD-----------KITEMIPMGHLGDPEDVADVVAFL 240 I N PG + TPM ++ ++V + + + I +G L +PEDVA V++L Sbjct: 175 ITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYL 234 Query: 241 ASEDSGYITGTSVEVTGGLF 260 AS DS Y+TG S+ + GG+ Sbjct: 235 ASPDSDYMTGQSLLIDGGMV 254 >3VZS-A nrPDB Length = 257 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 90/251 (35%), Positives = 138/251 (54%), Gaps = 10/251 (3%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAA-CDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +A VTG GIG A+ RLA +G V A C + ++ + G + Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGF-------DFI 67 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 A + +V++ + + ++V++ V+++ AGIT+D M+ DWD VI NL Sbjct: 68 ASEGNVADWDSTKTAFDKVKSEVGE-VDVLINNAGITRDVVFRKMTRADWDAVIDTNLTS 126 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F VT+ + G G I+NISS+ G+ G GQTNY+ +KAG+ G T A+E+ Sbjct: 127 LFNVTKQVIDGMADRGW-GRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATK 185 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 G+ N+V PG+IAT M + + Q V+DKI IP+ LG PE++A + A+L+SE+SG+ TG Sbjct: 186 GVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTG 245 Query: 251 TSVEVTGGLFM 261 + GGL M Sbjct: 246 ADFSLNGGLHM 256 >5VT6-A nrPDB Length = 269 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 92/251 (36%), Positives = 139/251 (55%), Gaps = 9/251 (3%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +A VTG G+G A+S RL G VA E + E + A Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSH------SERNDHVSTWLMHERDAGRDFKA 79 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 + DV++ + E+V A F + V+++ AGIT+D + M++ DWD V+ +L Sbjct: 80 YAVDVADFESCERCAEKVLADFGK-VDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAM 138 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHG 191 F VT+ +V G I+NI S+ G G GQ NYA++KAG+ G T+T A E + G Sbjct: 139 FNVTKQFIAGMVER-RFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRG 197 Query: 192 IRCNSVLPGFIATPMTQKVPQKVVD-KITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 I N+V PG++AT M + VPQ V++ KI IP+G LG P++VA ++AFL S+D+G++TG Sbjct: 198 ITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTG 257 Query: 251 TSVEVTGGLFM 261 + + GG+ M Sbjct: 258 ADLAINGGMHM 268 >6CI9-A nrPDB Length = 259 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 87/260 (33%), Positives = 132/260 (50%), Gaps = 10/260 (3%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + L A+VTG GIGR ++ A G V ++ TV L G Sbjct: 1 SHMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGT---- 56 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 RG A +ADV++ AR + + + +V + AGI L ++ DD ++ Sbjct: 57 ---RGKVTAVRADVTDPEDARRTVAETVSRHGGL-DIVCANAGIFPSGRLEDLTPDDIEQ 112 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-GNVGQTNYAASKAGVIGLTQ 181 V+ VN KGT + QAA QAL ++G G ++ SSI G + G G ++Y ASKA +G + Sbjct: 113 VLGVNFKGTVYIVQAALQALTASG-HGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLR 171 Query: 182 TAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 TAA EL I N+VLPG I T ++ Q +D++ IP G LG D+ + F A Sbjct: 172 TAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFA 231 Query: 242 SEDSGYITGTSVEVTGGLFM 261 ++++ Y+TG ++ V GG + Sbjct: 232 TDEAAYVTGQTLVVDGGQVL 251 >3O4R-A nrPDB Length = 261 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 83/264 (31%), Positives = 131/264 (49%), Gaps = 15/264 (5%) Query: 1 MASQLQNR---LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG 57 MAS R L + +ALVT + GIG A++ RLA +GA V + + V L G Sbjct: 2 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 61 Query: 58 PGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD-EFLLHMS 116 G + V +A L+ ++VS A + ++ ++ Sbjct: 62 EGL-------SVTGTVCHVGKAEDRERLVATAVKLHGGI-DILVSNAAVNPFFGSIMDVT 113 Query: 117 EDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGV 176 E+ WDK + +N+K L+T+A + G GS++ +SSI + G + Y SK + Sbjct: 114 EEVWDKTLDINVKAPALMTKAVVPEMEKRG-GGSVVIVSSIAAFSPSPGFSPYNVSKTAL 172 Query: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVA 234 +GLT+T A EL IR N + PG I T ++ + ++ + + E + + LG+PED A Sbjct: 173 LGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCA 232 Query: 235 DVVAFLASEDSGYITGTSVEVTGG 258 +V+FL SED+ YITG +V V GG Sbjct: 233 GIVSFLCSEDASYITGETVVVGGG 256 >5OVL-A nrPDB Length = 300 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 89/251 (35%), Positives = 134/251 (53%), Gaps = 20/251 (7%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S LVTG GIG A++ RLA +G VA A + Sbjct: 68 SRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL------------------F 109 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 Q DV+++ A ++V+ P V+V+ AGI++D FL+ M+E+ +++VI NL G Sbjct: 110 GVQCDVTDSAAVDRAFKEVEEHQG-PVEVLVANAGISKDAFLMRMTEERFEEVINTNLTG 168 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F Q A++ + G II I S+ G G Q NYAA+KAG+IG+ ++ +REL + Sbjct: 169 AFRCAQRASRTM-QRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKA 227 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 G+ N V PG+I T MT+ + +++ + IP +G E+VA V+FLASED+ YI G Sbjct: 228 GVTANVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAG 287 Query: 251 TSVEVTGGLFM 261 + V GG+ M Sbjct: 288 AVIPVDGGMGM 298 >4IIN-A nrPDB Length = 271 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 132/255 (51%), Gaps = 10/255 (3%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVR-LLGGPGSKEGPPR 66 + L+TGA GIG ++ LA G V A + ++ L G K Sbjct: 26 QFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYK----- 80 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 A + D + ++ + +V+ AG+ +D+ + M +D+ VI Sbjct: 81 --AAVIKFDAASESDFIEAIQTIVQSDGGLSY-LVNNAGVVRDKLAIKMKTEDFHHVIDN 137 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 NL F+ + A + + + GS++N++SI+G+ GN+GQTNY+ASK G+I ++++ A E Sbjct: 138 NLTSAFIGCREALKVMSKS-RFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYE 196 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 IR NSV PGFI T M + ++ + IP+ LG ++VA+ VAFL S+ S Sbjct: 197 GALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSS 256 Query: 247 YITGTSVEVTGGLFM 261 YITG +++V GGL+M Sbjct: 257 YITGETLKVNGGLYM 271 >1AE1-A nrPDB Length = 273 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 119/257 (46%), Gaps = 14/257 (5%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ ALVTG GIG A+ LAG GA V C + E + + G N Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGL-------N 71 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 D+ L++ V F +++V+ AG+ + +E D++ ++ N Sbjct: 72 VEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNF 131 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 + + ++Q A L ++ G++I +SSI G + Y+ASK + +T++ A E Sbjct: 132 EAAYHLSQIAYPLLKAS-QNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWA 190 Query: 189 RHGIRCNSVLPGFIATPMTQKVP------QKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 + IR NSV PG I TP+ + ++ +D PMG G P++V+ ++AFL Sbjct: 191 KDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCF 250 Query: 243 EDSGYITGTSVEVTGGL 259 + YITG + GG Sbjct: 251 PAASYITGQIIWADGGF 267 >2EW8-A nrPDB Length = 249 Score = 243 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 82/261 (31%), Positives = 130/261 (49%), Gaps = 19/261 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRA-AAQETVRLLGGPGSKEG 63 + RL+ LA++TG +GIGRA++ R A EGA +A DL A A+ +R LG Sbjct: 1 MTQRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLG------- 53 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 + DVS+ +QV + F R ++V+ AGI ++ + W K Sbjct: 54 ---RRVLTVKCDVSQPGDVEAFGKQVISTFGR-CDILVNNAGIYPLIPFDELTFEQWKKT 109 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 +N+ FL+ +A + NG G IIN++S + T+Y ++KA IG T+ Sbjct: 110 FEINVDSGFLMAKAFVPGMKRNGW-GRIINLTSTTYWLKIEAYTHYISTKAANIGFTRAL 168 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQ----KVPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 A +LG+ GI N++ P + T T+ V+ + + IP L P D+ AF Sbjct: 169 ASDLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAF 226 Query: 240 LASEDSGYITGTSVEVTGGLF 260 LAS+D+ +ITG ++ V GG+ Sbjct: 227 LASDDASFITGQTLAVDGGMV 247 >4Z9Y-A nrPDB Length = 253 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 12/254 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +AL+TG +G+G+ +++ LA G + ++ ++T+ + G + Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNI--VEPKDTIEKVTALGRR------- 58 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 + AD+S L+E+ A F ++V+ AGI + E + SE +WD V+ +N+ Sbjct: 59 FLSLTADMSNVSGHAELVEKAVAEFGH-VDILVNNAGIIRREDAIEFSEKNWDDVMNLNI 117 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 K F ++Q A+ + G G IINI+S++ G + +Y ASK+ V+G+T+ A E Sbjct: 118 KSVFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWA 177 Query: 189 RHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 +HGI N++ PG++AT TQ++ ++ +I + IP G G P+D+ FLAS S Sbjct: 178 KHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASD 237 Query: 247 YITGTSVEVTGGLF 260 YI G ++ V GG Sbjct: 238 YINGYTIAVDGGWL 251 >6NRP-A nrPDB Length = 263 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 85/247 (34%), Positives = 133/247 (53%), Gaps = 12/247 (4%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDR-AAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 LVTG+ GIG+A++++LA G V R A A++ V+ + G N Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQ-------NSHYLM 80 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 DV+E + + +LEQ VV++ AG+T D +++ DWD+VI+ +L G + Sbjct: 81 FDVNERQTVQQILEQDVEQHGGFYGVVLN-AGLTHDGAFPALTDQDWDEVISTSLDGFYN 139 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 V + ++ G I+ +SS+ G +GN GQ NY+A+KAG+IG T+ A EL + I Sbjct: 140 VLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKIT 199 Query: 194 CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSV 253 N V PG I T M +V + +MIP+ +G ++VA VV FL S+++ Y+T + Sbjct: 200 VNCVAPGLIETEMVT---DEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVI 256 Query: 254 EVTGGLF 260 V GGL Sbjct: 257 SVNGGLI 263 >3UVE-A nrPDB Length = 286 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 82/282 (29%), Positives = 127/282 (45%), Gaps = 26/282 (9%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL---------DRAAAQETVRLL 55 + R+ +A VTGA G GR+ +VRLA EGA + A D+ D A T L Sbjct: 5 MTGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDL 64 Query: 56 GGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDE-FLLH 114 + DV + A + ++ R ++V+ AGI L Sbjct: 65 AETADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRL-DIIVANAGIGNGGDTLDK 123 Query: 115 MSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKA 174 SE+DW ++I +NL G + +A +++ G GSII SS+ G +Y A+K Sbjct: 124 TSEEDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKH 183 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK----------VPQKVVDKITEMIPM 224 GV+GL + ELG+H IR NSV P + TPM + D + + M Sbjct: 184 GVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQM 243 Query: 225 GH-----LGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 H +P D+++ V F AS+++ YITG ++ + G + Sbjct: 244 FHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >2AE2-A nrPDB Length = 260 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 123/258 (47%), Gaps = 13/258 (5%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 L ALVTG GIG + LA GA+V C ++ + + G K Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFK------ 59 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A D+S + L+ V F +++V+ AGI + + +D+ ++++N Sbjct: 60 -VEASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSIN 118 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 + + ++ A + RG+++ ISS+ G + + Y A+K + LT+ A E Sbjct: 119 FEAAYHLS-VLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEW 177 Query: 188 GRHGIRCNSVLPGFIAT---PMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 + IR N V PG IAT MT + P+ + ++K+ + + +G+P+++A +VAFL Sbjct: 178 AKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCF 237 Query: 243 EDSGYITGTSVEVTGGLF 260 + Y+TG + V GGL Sbjct: 238 PAASYVTGQIIYVDGGLM 255 >1YXM-A nrPDB Length = 303 Score = 239 bits (611), Expect = 7e-64, Method: Composition-based stats. Identities = 75/269 (27%), Positives = 115/269 (42%), Gaps = 16/269 (5%) Query: 1 MASQLQNR-------LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVR 53 MAS + R L+ +A+VTG +GIG+A+ L G+ V + Sbjct: 1 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD 60 Query: 54 LLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLL 113 L + Q ++ L++ F + + +V+ G Sbjct: 61 ELQAN--LPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKI-NFLVNNGGGQFLSPAE 117 Query: 114 HMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASK 173 H+S W V+ NL GTF + +A + + GSI+NI + K G + A++ Sbjct: 118 HISSKGWHAVLETNLTGTFYMCKAVYSSWMKEH-GGSIVNII-VPTKAGFPLAVHSGAAR 175 Query: 174 AGVIGLTQTAARELGRHGIRCNSVLPGFIAT----PMTQKVPQKVVDKITEMIPMGHLGD 229 AGV LT++ A E GIR N V PG I + Q + + IP +G Sbjct: 176 AGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGV 235 Query: 230 PEDVADVVAFLASEDSGYITGTSVEVTGG 258 PE+V+ VV FL S + +ITG SV+V GG Sbjct: 236 PEEVSSVVCFLLSPAASFITGQSVDVDGG 264 >5OVJ-A nrPDB Length = 256 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 89/251 (35%), Positives = 134/251 (53%), Gaps = 20/251 (7%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S LVTG GIG A++ RLA +G VA A + Sbjct: 24 SRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL------------------F 65 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 Q DV+++ A ++V+ P V+V+ AGI++D FL+ M+E+ +++VI NL G Sbjct: 66 GVQCDVTDSAAVDRAFKEVEEHQG-PVEVLVANAGISKDAFLMRMTEERFEEVINTNLTG 124 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F Q A++ + G II I S+ G G Q NYAA+KAG+IG+ ++ +REL + Sbjct: 125 AFRCAQRASRTM-QRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKA 183 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 G+ N V PG+I T MT+ + +++ + IP +G E+VA V+FLASED+ YI G Sbjct: 184 GVTANVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAG 243 Query: 251 TSVEVTGGLFM 261 + V GG+ M Sbjct: 244 AVIPVDGGMGM 254 >1NFF-A nrPDB Length = 260 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 81/254 (31%), Positives = 122/254 (48%), Gaps = 17/254 (6%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + RL +ALV+G G+G + + EGA V D+ + + Sbjct: 1 MSGRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGK----------AMAAE 50 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 DV++ + ++ F V+V+ AGI + + +W +++ Sbjct: 51 LADAARYVHLDVTQPAQWKAAVDTAVTAFGGLH-VLVNNAGILNIGTIEDYALTEWQRIL 109 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 VNL G FL +A + + G RGSIINISSI G G V Y A+K V GLT++ A Sbjct: 110 DVNLTGVFLGIRAVVKPMKEAG-RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTA 168 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASED 244 ELG GIR NS+ PG + TPMT VP+ + +G +P +V+++V +LAS++ Sbjct: 169 LELGPSGIRVNSIHPGLVKTPMTDWVPEDIF-----QTALGRAAEPVEVSNLVVYLASDE 223 Query: 245 SGYITGTSVEVTGG 258 S Y TG V GG Sbjct: 224 SSYSTGAEFVVDGG 237 >4IIV-A nrPDB Length = 267 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 92/258 (35%), Positives = 132/258 (51%), Gaps = 10/258 (3%) Query: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACD-LDRAAAQETVRLLGGPGSKE 62 Q+ S LVTGA GIGRA++ +LA +G + D A AQET+ + G Sbjct: 19 YFQSNAMSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANG--- 75 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 GN DV+ R +LE A V VS AGI +D +S DDWD Sbjct: 76 ----GNGRLLSFDVANREQCREVLEHEIAQHGAWYGV-VSNAGIARDAAFPALSNDDWDA 130 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 VI NL + V Q ++ G II +SS+ G +GN GQ NY+A+KAG+IG T+ Sbjct: 131 VIHTNLDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKA 190 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 A EL + I N + PG I T M + + + + + MIPM +G E+VA + ++L S Sbjct: 191 LAIELAKRKITVNCIAPGLIDTGMIE-MEESALKEAMSMIPMKRMGQAEEVAGLASYLMS 249 Query: 243 EDSGYITGTSVEVTGGLF 260 + +GY+T + + GG+ Sbjct: 250 DIAGYVTRQVISINGGML 267 >4IS3-A nrPDB Length = 268 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 78/257 (30%), Positives = 126/257 (49%), Gaps = 7/257 (2%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 Q N ++ + ++TG GIG A + GA V+ + + L KE Sbjct: 17 FQGMNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQL-----KE 71 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 P F D++ A + QV + R V+++ AGIT + +SE+++ Sbjct: 72 LYPEEEVLGFAPDLTSRDAVMAAVGQVAQKYGRL-DVMINNAGITSNNVFSRVSEEEFKH 130 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 ++ +N+ G F A Q + + +G IIN +S+ G G++ Y ASKA VIGLT Sbjct: 131 IMDINVTGVFNGAWCAYQCM-KDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHG 189 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 RE+ R IR V PG + T MT P ++++ + +PM + +PE++A+V FLAS Sbjct: 190 LGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLAS 249 Query: 243 EDSGYITGTSVEVTGGL 259 + + IT T+V V G Sbjct: 250 DLASGITATTVSVDGAY 266 >3WYE-A nrPDB Length = 256 Score = 238 bits (607), Expect = 3e-63, Method: Composition-based stats. Identities = 91/260 (35%), Positives = 136/260 (52%), Gaps = 19/260 (7%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +ALVTGAG GIG+A+++RL +G VA D + A A+ + G G+ A Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAG-------GHAVA 55 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 + DVS+ +EQ + V+V+ AGI Q + LL ++E+D ++ +VN+ Sbjct: 56 VKVDVSDRDQVFAAVEQARKTLGGF-DVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSV 114 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHG 191 F QAA +A G G IIN +SI G + Y+ +K V GLTQTAAR+L G Sbjct: 115 FFGIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLG 174 Query: 192 IRCNSVLPGFIATPMTQKVPQKV-----------VDKITEMIPMGHLGDPEDVADVVAFL 240 I N PG + T M +++ ++ + + I +G PEDVA +V+FL Sbjct: 175 ITVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFL 234 Query: 241 ASEDSGYITGTSVEVTGGLF 260 AS DS Y+TG S+ + GG+ Sbjct: 235 ASPDSDYMTGQSLLIDGGMV 254 >5T5Q-A nrPDB Length = 247 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 79/257 (30%), Positives = 126/257 (49%), Gaps = 13/257 (5%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 ++ + ++TGA GIGRA++ GA + DLDR LG P Sbjct: 3 MKFEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSP------ 56 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 A +AD S A A + F +V AGI Q + MS+ DW + I Sbjct: 57 --ERIATIKADASSADDAEKTVALAMERFGGI-DFLVPSAGIYQAKPFAEMSDADWHRTI 113 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 ++NL G F + + A AL + SI+ ++S+ G +Y A+K ++ +T+ + Sbjct: 114 SINLDGVFYLCKRALPALKEDS---SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALS 170 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASED 244 REL R N V PG I TPMT ++ + +D+ P+ LG P ++A V+AFL S Sbjct: 171 RELAPK-TRVNGVSPGIIETPMTSELLKTRMDETMTQTPLKRLGKPSEIASVIAFLCSPA 229 Query: 245 SGYITGTSVEVTGGLFM 261 + ++TG +++V GG++M Sbjct: 230 ASFVTGETIQVNGGIYM 246 >3WTC-A nrPDB Length = 262 Score = 237 bits (604), Expect = 6e-63, Method: Composition-based stats. Identities = 88/269 (32%), Positives = 133/269 (49%), Gaps = 21/269 (7%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + L +A VTGA GIG+A+++RLA +GA V D+ + ET + + G + Sbjct: 2 SHMS--LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRR- 58 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 A AD+S R L ++V+ AGI Q + +L + + +K Sbjct: 59 ------AVALTADISNRDQFRSTLADAAKTLGGL-DIMVNNAGICQVKPILDIEPAEIEK 111 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 + ++N++G QAAA G +G IIN SI G G Y+A+K V LTQ+ Sbjct: 112 IFSINVQGVLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQS 171 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVD-----------KITEMIPMGHLGDPE 231 AA+EL GI NS PG + T M + +++ + K E I +G + + Sbjct: 172 AAKELASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETAD 231 Query: 232 DVADVVAFLASEDSGYITGTSVEVTGGLF 260 DVA VA+L+S D+ Y+TG SV + GGL Sbjct: 232 DVAGFVAYLSSSDADYMTGQSVLIDGGLV 260 >5U9P-A nrPDB Length = 265 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 118/254 (46%), Gaps = 11/254 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL AL+TG+G GIG ++ LA GA + D + A R G Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHA-- 74 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 DV+E R +++ +A ++V+ AGI + L DDW ++ VN Sbjct: 75 -----VFDVAEHAQVRAAIDEFEARVGAI-DILVNNAGIQRRAPLDAFEPDDWHALMRVN 128 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L G F V QA A+ +++ G G IINI S+ ++ YAA+K V LT+ + Sbjct: 129 LDGVFNVAQAVARHMIARG-HGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADW 187 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDS 245 R+GI+ N + PG+ T + + + D + + P G G +++ FLAS S Sbjct: 188 ARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAAS 247 Query: 246 GYITGTSVEVTGGL 259 ++ G ++ V GGL Sbjct: 248 DFVNGQTLFVDGGL 261 >1UZM-A nrPDB Length = 247 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 91/251 (36%), Positives = 132/251 (52%), Gaps = 20/251 (7%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S LVTG GIG A++ RLA +G VA A + Sbjct: 15 SRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPK------------------GLF 56 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 + DV+++ A P V+VS AG++ D FL+ M+E+ ++KVI NL G Sbjct: 57 GVEVDVTDSDAVDRAF-TAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTG 115 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 F V Q A++++ G +I I S+ G G Q NYAASKAGVIG+ ++ AREL + Sbjct: 116 AFRVAQRASRSM-QRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKA 174 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 + N V PG+I T MT+ + +++ + IP +G P +VA VV+FLASED+ YI+G Sbjct: 175 NVTANVVAPGYIDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISG 234 Query: 251 TSVEVTGGLFM 261 + V GG+ M Sbjct: 235 AVIPVDGGMGM 245 >3T7C-A nrPDB Length = 299 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 80/278 (28%), Positives = 127/278 (45%), Gaps = 22/278 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAA-----AQETVRLLGGPG 59 + ++ +A +TGA G GR+ ++ LA EGA + A D+ + T L Sbjct: 22 MAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETV 81 Query: 60 SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD 119 + A Q DV + A + ++ R V+ + A ++ L M Sbjct: 82 RQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKT 141 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 W +I VNL G ++ + A +++ GSI+ SSI G G NY ASK G+ GL Sbjct: 142 WRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGL 201 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ----------------KVVDKITEMIP 223 +T A ELG IR N V P +ATPM P +V + ++P Sbjct: 202 MRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLP 261 Query: 224 MGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 + ++ +P D+++ + FL S+D+ YITG S+ V GG + Sbjct: 262 IPYV-EPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >2ZAT-A nrPDB Length = 260 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 80/256 (31%), Positives = 124/256 (48%), Gaps = 12/256 (4%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 + L + +ALVT + GIG A++ RLA +GA V + TV L G G Sbjct: 9 RKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGL----- 63 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD-EFLLHMSEDDWDKVI 124 + V +A L+ ++VS A + ++ +E+ WDK++ Sbjct: 64 --SVTGTVCHVGKAEDRERLVAMAVNLHGG-VDILVSNAAVNPFFGNIIDATEEVWDKIL 120 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 VN+K T L+T+A + G GS++ +SS+ Y SK ++GLT+ A Sbjct: 121 HVNVKATVLMTKAVVPEMEKRG-GGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLA 179 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 EL IR N + PG I T +Q + + + + E + + LG+PED A +V+FL S Sbjct: 180 VELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCS 239 Query: 243 EDSGYITGTSVEVTGG 258 ED+ YITG +V V GG Sbjct: 240 EDASYITGETVVVGGG 255 >4CQM-B nrPDB Length = 244 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 84/251 (33%), Positives = 133/251 (52%), Gaps = 17/251 (6%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 + V G GIGRAV+ +A +G +A + A+ LG G+H Sbjct: 9 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG----------GDHL 58 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 AF DV++ + E+++ R + +V+ AGI +D L+ +D + NL G Sbjct: 59 AFSCDVAKEHDVQNTFEELEKHLGR-VNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLG 117 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 + L +AA + ++ GSI+N+ SIVG GN GQ+ Y+ASK G++G ++ A+E+ R Sbjct: 118 SMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK 176 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITG 250 IR N V PGF+ T MT+ + + + + + IP+G G+ +VA V FL +S YITG Sbjct: 177 KIRVNVVAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITG 231 Query: 251 TSVEVTGGLFM 261 + V GGL + Sbjct: 232 HVLVVDGGLQL 242 >3RWB-A nrPDB Length = 247 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 90/256 (35%), Positives = 132/256 (51%), Gaps = 12/256 (4%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 RL ALVTGA GIG+A++ RLA +GATV D++ A+ +G Sbjct: 1 TERLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKAR----- 55 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 A AD+S+ + + L ++QA ++V+ A I + D W K+I Sbjct: 56 -----AIAADISDPGSVKALFAEIQALTGGI-DILVNNASIVPFVAWDDVDLDHWRKIID 109 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VNL GTF+VT+A + + G G +I+I+S G Y A+K GVIG T+ A Sbjct: 110 VNLTGTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALAT 169 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMI-PMGHLGDPEDVADVVAFLASED 244 ELG++ I N+V PG I + + P EM+ M G PE +ADVV+FLAS+D Sbjct: 170 ELGKYNITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDD 229 Query: 245 SGYITGTSVEVTGGLF 260 + +ITG ++ V G+ Sbjct: 230 ARWITGQTLNVDAGMV 245 >4RZI-B nrPDB Length = 240 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 93/253 (36%), Positives = 129/253 (50%), Gaps = 20/253 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L + +VTG GIG A+ L GA VA DL Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA---------------- 49 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A+V++ + ++ P VV+ AGIT+D F ++ DWD V+ VNL Sbjct: 50 -LGVVANVTDLESMTAAAAEITDKLG-PVYGVVANAGITKDNFFPKLTPADWDAVLNVNL 107 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 KG + + + GSI+ ISSI G+ GNVGQTNY+A+KAGVIG+ ++ ARE Sbjct: 108 KGVAYSIKPFIEGMYER-KAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGA 166 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASE-DSGY 247 R+G+R N+V PGFI T MT + + + +KIT+ IP G PE++A VAFL S S Y Sbjct: 167 RYGVRANAVAPGFIDTEMTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSY 226 Query: 248 ITGTSVEVTGGLF 260 +TG + V G Sbjct: 227 VTGEVLRVNGAHH 239 >2Q2Q-A nrPDB Length = 255 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 77/263 (29%), Positives = 116/263 (44%), Gaps = 22/263 (8%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ ALVTG+ SGIG ++ LA GA + A + + G K Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPA--LAEIARHGVKAVHH--- 56 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 AD+S+ L + F ++V+ AGI + + WDK+IA+NL Sbjct: 57 ----PADLSDVAQIEALFALAEREFGG-VDILVNNAGIQHVAPVEQFPLESWDKIIALNL 111 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F T+ A + + G IINI+S+ G VG+ G+ Y A+K GV+GLT+ E Sbjct: 112 SAVFHGTRLALPGMRARNW-GRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETA 170 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVV-----------DKITEMIPMGHLGDPEDVADVV 237 + CN++ PG++ TP+ QK D + E P PE + ++V Sbjct: 171 TSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELV 230 Query: 238 AFLASEDSGYITGTSVEVTGGLF 260 FL SE + G + V GG Sbjct: 231 LFLCSEAGSQVRGAAWNVDGGWL 253 >5OJG-A nrPDB Length = 260 Score = 228 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 79/257 (30%), Positives = 121/257 (47%), Gaps = 14/257 (5%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 R +A+VT A GIG A++ RL EGA+V ++ E + L G + Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD-EFLLHMSEDDWDKVIAV 126 H A + L++ F + +++V+ GI +L +S+ WDK+ V Sbjct: 67 GHIA------STDDQKKLVDFTLQKFGKI-NILVNNHGINPAFGHILEVSDQVWDKLFEV 119 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 N+K F +T+ + G G+II +S G Y +K ++GLT+ A Sbjct: 120 NVKAGFQMTKLVHPHIAKEG-GGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMG 178 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEM-----IPMGHLGDPEDVADVVAFLA 241 L + IR N + PG I T M+Q + D E+ I +G LG P+D A VA+LA Sbjct: 179 LAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLA 238 Query: 242 SEDSGYITGTSVEVTGG 258 S+DS YITG + + GG Sbjct: 239 SDDSSYITGEMIIIAGG 255 >3W8F-A nrPDB Length = 260 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 79/263 (30%), Positives = 123/263 (46%), Gaps = 19/263 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ A+VTG+ SGIG A++ LA GA V + E R + E Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERS-----TLESKFGVK 56 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 AD+S+A+A R + + ++V+ AGI + D W+ +IA+NL Sbjct: 57 AYYLNADLSDAQATRDFIAKAAEALGGL-DILVNNAGIQHTAPIEEFPVDKWNAIIALNL 115 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F T AA + G G IINI+S G V +V ++ Y A+K GV+GLT+ A E Sbjct: 116 SAVFHGTAAALPIMQKQGW-GRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENA 174 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDK------------ITEMIPMGHLGDPEDVADV 236 GI CN++ PG++ TP+ +K + + + + E P PE + Sbjct: 175 GKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGA 234 Query: 237 VAFLASEDSGYITGTSVEVTGGL 259 FL+S + +TGT++ + GG Sbjct: 235 AVFLSSAAADQMTGTTLSLDGGW 257 >5EJ2-A nrPDB Length = 308 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 80/279 (28%), Positives = 128/279 (45%), Gaps = 24/279 (8%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-----DRAAAQETVRLLGGPG 59 + R+ +A ++GA G GR+ +VRLA EGA + A D+ + A T L Sbjct: 31 MTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETA 90 Query: 60 SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF-LLHMSED 118 Q DV + A + ++ R ++V+ AG+ D L + ++ Sbjct: 91 DLVKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRL-DIIVANAGVGTDGRKLHKIRDN 149 Query: 119 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 W +I +NL G + +A ++S G GSI+ SS+ G+ +Y A+K GVIG Sbjct: 150 VWQDMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIG 209 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKV--------------PQKVV--DKITEMI 222 L + A ELG H IR N+VLP ++T M P ++ + Sbjct: 210 LMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTL 269 Query: 223 PMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 P+ D D+++ V FLAS++S Y+TG S+ V G + Sbjct: 270 PVP-WVDASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >4DBZ-A nrPDB Length = 281 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 87/270 (32%), Positives = 129/270 (47%), Gaps = 23/270 (8%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + + S +ALVTGA SGIG ++ RL EG V C + T++ L G + Sbjct: 19 SHMATQ-DSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEA 77 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 DV L+ V + P V+V+ AG ++++ W Sbjct: 78 D-------GRTCDVRSVPEIEALVAAVVERYG-PVDVLVNNAGRPGGGATAELADELWLD 129 Query: 123 VIAVNLKGTFLVTQAAAQA--LVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 V+ NL G F VT+ +A ++ G G I+NI+S GK G V Y+ASK GV+G T Sbjct: 130 VVETNLTGVFRVTKQVLKAGGMLERGT-GRIVNIASTGGKQGLVHAAPYSASKHGVVGFT 188 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKV-----------PQKVVDKITEMIPMGHLGD 229 + EL R GI N+V PGF+ TPM V ++ D+IT +P+G Sbjct: 189 KALGLELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQ 248 Query: 230 PEDVADVVAFLASEDSGYITGTSVEVTGGL 259 P +VA++VA+L + +T ++ V GGL Sbjct: 249 PSEVAEMVAYLIGPGAAAVTAQALNVCGGL 278 >1K2W-A nrPDB Length = 256 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 78/265 (29%), Positives = 130/265 (49%), Gaps = 22/265 (8%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL AL+TG+ GIGRA + EGA VA D++ AA+ T +G Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAA-------- 53 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A DV++ + + ++ + ++V+ A + ++ ++ + +D++ A+N Sbjct: 54 --CAIALDVTDQASIDRCVAELLDRWGSI-DILVNNAALFDLAPIVEITRESYDRLFAIN 110 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 + GT + QA A+A+++ G G IIN++S G+ G Y A+KA VI LTQ+A L Sbjct: 111 VSGTLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNL 170 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVD-----------KITEMIPMGHLGDPEDVADV 236 RHGI N++ PG + V K D ++ +P G +G ED+ + Sbjct: 171 IRHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGM 230 Query: 237 VAFLASEDSGYITGTSVEVTGGLFM 261 FLA+ ++ YI + V GG +M Sbjct: 231 AIFLATPEADYIVAQTYNVDGGNWM 255 >1X1T-A nrPDB Length = 260 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 81/263 (30%), Positives = 123/263 (46%), Gaps = 19/263 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +A+VTG+ SGIG ++ LA +GA + AA E VR Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVR-----AGLAAQHGVK 56 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 AD+S+ A R L++ R ++V+ AGI + + WD ++A+NL Sbjct: 57 VLYDGADLSKGEAVRGLVDNAVRQMGRI-DILVNNAGIQHTALIEDFPTEKWDAILALNL 115 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F T AA + G G IINI+S G V + ++ Y A+K GV+G T+ A E Sbjct: 116 SAVFHGTAAALPHMKKQG-FGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETA 174 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDK------------ITEMIPMGHLGDPEDVADV 236 GI N++ PG++ TP+ +K + +K ++E P PE + Sbjct: 175 GQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGT 234 Query: 237 VAFLASEDSGYITGTSVEVTGGL 259 FLAS+ + ITGT+V V GG Sbjct: 235 AVFLASDAAAQITGTTVSVDGGW 257 >4HP8-A nrPDB Length = 247 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 87/254 (34%), Positives = 128/254 (50%), Gaps = 17/254 (6%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L ALVTGA +G+G+A++V LA GA V A ET+ ++ G GN Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAAR--RAPDETLDIIAKDG-------GN 57 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 +A D ++ AA+ ++V+ AGI + + SE DWD+V+ VNL Sbjct: 58 ASALLIDFADPLAAKDSFTDA------GFDILVNNAGIIRRADSVEFSELDWDEVMDVNL 111 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 K F TQA A+ L++ G G ++NI+S++ G + +Y A+K GV GLT+ A E Sbjct: 112 KALFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWA 171 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVV--DKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 GI N++ PG+I T T+ + I E IP G G ED+A FL+S + Sbjct: 172 AKGINVNAIAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAAD 231 Query: 247 YITGTSVEVTGGLF 260 Y+ G + V GG Sbjct: 232 YVHGAILNVDGGWL 245 >3V2H-A nrPDB Length = 281 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 74/266 (27%), Positives = 121/266 (45%), Gaps = 19/266 (7%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 + + A++TG+ SGIG A++ LA GA + TV G Sbjct: 20 FQSMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTV-----TDEVAGLS 74 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 G AD+++ ++ V F ++V+ AG+ E + + WD++IA Sbjct: 75 SGTVLHHPADMTKPSEIADMMAMVADRFGGA-DILVNNAGVQFVEKIEDFPVEQWDRIIA 133 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 VNL +F + A + G G IINI+S G V + ++ Y A+K G++GLT+T A Sbjct: 134 VNLSSSFHTIRGAIPPMKKKGW-GRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVAL 192 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVV------------DKITEMIPMGHLGDPEDV 233 E+ G+ NS+ PG++ TP+ +K + + + P E V Sbjct: 193 EVAESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQV 252 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGL 259 A + +LA +D+ ITGT V + GG Sbjct: 253 ASLALYLAGDDAAQITGTHVSMDGGW 278 >4E6P-A nrPDB Length = 259 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 78/268 (29%), Positives = 126/268 (47%), Gaps = 22/268 (8%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + RL AL+TG+ GIGRA + EGATVA D+D A++ +G Sbjct: 2 MMKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAA----- 56 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 A Q DV+ + + ++V+ A + ++ ++ + ++K+ Sbjct: 57 -----YAVQMDVTRQDSIDAAIAATVEHAGGL-DILVNNAALFDLAPIVEITRESYEKLF 110 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 A+N+ GT QAAA+ +++ G G IIN++S G+ G Y A+KA VI LTQ+A Sbjct: 111 AINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAG 170 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKVP-----------QKVVDKITEMIPMGHLGDPEDV 233 +L +H I N++ PG + V + + E +P G +G ED+ Sbjct: 171 LDLIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDL 230 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGLFM 261 + FLAS +S YI + V GG +M Sbjct: 231 TGMAIFLASAESDYIVSQTYNVDGGNWM 258 >3V2G-A nrPDB Length = 271 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 86/252 (34%), Positives = 124/252 (49%), Gaps = 14/252 (5%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAA-AQETVRLLGGPGSKEGPPRG 67 L A VTG GIG A++ RLA EGA VA ++ A AQ V + G G Sbjct: 29 LAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAG-------G 81 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A +AD +A A + + ++V+ AGI L + D+D+V+AVN Sbjct: 82 RAVAIRADNRDAEAIEQAIRETVEALGGL-DILVNSAGIWHSAPLEETTVADFDEVMAVN 140 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVG-KVGNVGQTNYAASKAGVIGLTQTAARE 186 + F+ ++A++ L G G II I S + V G + Y+ASKA + GLT+ AR+ Sbjct: 141 FRAPFVAIRSASRHL---GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARD 197 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 LG GI N V PG T M + E I G G+P+D+A +VA+LA Sbjct: 198 LGPRGITVNIVHPGSTDTDMN-PADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQGK 256 Query: 247 YITGTSVEVTGG 258 ++TG S+ + GG Sbjct: 257 FVTGASLTIDGG 268 >3A28-C nrPDB Length = 258 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 84/263 (31%), Positives = 133/263 (50%), Gaps = 21/263 (7%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDR--AAAQETVRLLGGPGSKEGPPRGN 68 S +A+VTG GIGR +S +LA +G +A DL + A ET++L+ K Sbjct: 2 SKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQK------- 54 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 DV++ +++ V+V+ AGI Q + LL ++E+D ++ +VN+ Sbjct: 55 AVFVGLDVTDKANFDSAIDEAAEKLGGF-DVLVNNAGIAQIKPLLEVTEEDLKQIYSVNV 113 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 F QAA++ G +G IIN +SI G + Y+ +K V GLTQ AA+EL Sbjct: 114 FSVFFGIQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELA 173 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKV-----------VDKITEMIPMGHLGDPEDVADVV 237 G N+ PG + T M +++ ++ + + I +G PEDVA +V Sbjct: 174 PKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLV 233 Query: 238 AFLASEDSGYITGTSVEVTGGLF 260 +FLASE+S Y+TG + V GG+ Sbjct: 234 SFLASENSNYVTGQVMLVDGGML 256 >5YSS-A nrPDB Length = 256 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 75/265 (28%), Positives = 124/265 (46%), Gaps = 24/265 (9%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEGPPR 66 L ALVTG+ SGIG ++ LA GAT+ D AA++ V G G Sbjct: 2 NLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHG--- 58 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 AD+S+ ++ ++ F ++++ AGI + D W+ +IA+ Sbjct: 59 -------ADLSDEAQIADMMRYAESEFGG-VDILINNAGIQHVSPIETFPVDKWNAIIAI 110 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 NL F T+ A + + G IINI+S+ G V + ++ Y A+K GV+GLT+T A E Sbjct: 111 NLSSVFHTTRLALPGMRARNW-GRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALE 169 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDK-----------ITEMIPMGHLGDPEDVAD 235 + I CN++ PG++ TP+ Q+ K + + + E P PE + + Sbjct: 170 TAQTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGN 229 Query: 236 VVAFLASEDSGYITGTSVEVTGGLF 260 + FL S+ + + G + + GG Sbjct: 230 LALFLCSDGAAQVRGVAWNMDGGWV 254 >4MOW-A nrPDB Length = 256 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 84/258 (32%), Positives = 131/258 (50%), Gaps = 15/258 (5%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD-RAAAQETVRLLGGPGSKEGP 64 ++L +A+VTGA GIG A++ LA EGA V +A A V + G Sbjct: 9 MSKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAG----- 63 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 G A DVS+A A+ +++ + R V+V+ +G+ + + ++E+ + + Sbjct: 64 --GRAVAVGGDVSKAADAQRIVDTAIETYGRL-DVLVNNSGVYEFAPIEAITEEHYRRQF 120 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 N+ G L TQAA + L G SIINISS+V + Y+ +K V +T A Sbjct: 121 DTNVFGVLLTTQAAVKHL---GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLA 177 Query: 185 RELGRHGIRCNSVLPGFIATPMTQK---VPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 ELG IR N++ PG I T T + + ++ P+G LG+P D+A V FLA Sbjct: 178 LELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLA 237 Query: 242 SEDSGYITGTSVEVTGGL 259 S+D+ ++TG + V+GGL Sbjct: 238 SDDARWMTGEHLVVSGGL 255 >3U5T-A nrPDB Length = 267 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 90/252 (35%), Positives = 128/252 (50%), Gaps = 11/252 (4%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + +A+VTGA GIG A++ RLA +G TV +AAA E V K G Sbjct: 26 TNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVA------GKIEAAGGKA 79 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 QADVS+ A R L + F V+V+ AGI + + +D+VIAVNLK Sbjct: 80 LTAQADVSDPAAVRRLFATAEEAFGG-VDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLK 138 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGR 189 GTF + AAQ L G IIN+S+ + + YAA+KAGV +T ++EL Sbjct: 139 GTFNTLREAAQRLR---VGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRG 195 Query: 190 HGIRCNSVLPGFIATPM-TQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 I N+V PG AT + + +V D+ ++ P+ LG P+D+A VAFLA D ++ Sbjct: 196 RDITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWV 255 Query: 249 TGTSVEVTGGLF 260 G + GG+ Sbjct: 256 NGQVLRANGGII 267 >2CFC-A nrPDB Length = 250 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 86/254 (33%), Positives = 128/254 (50%), Gaps = 13/254 (5%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +A+VTGA SG G A++ R G VAA DL +ET R + + Sbjct: 2 SRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADK------VL 55 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGIT---QDEFLLHMSEDDWDKVIAVN 127 +ADV++ + F V+V+ AGIT + L + +DKV+AVN Sbjct: 56 RVRADVADEGDVNAAIAATMEQFGAI-DVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 ++G FL +A ++ G G I+NI+S+ V G++ Y SK V+ LT++ A + Sbjct: 115 VRGIFLGCRAVLPHMLLQGA-GVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDY 173 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 GIRCN+V PG I TPMTQ ++ D++ IP +G VAD V FLA ED+ Sbjct: 174 AGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDA 233 Query: 246 GYITGTSVEVTGGL 259 Y+ G ++ + G Sbjct: 234 TYVNGAALVMDGAY 247 >3D3W-A nrPDB Length = 244 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 116/258 (44%), Gaps = 18/258 (6%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 ++ L LVTGAG GIGR L GA V A +A VR G Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG------- 53 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 D+ + A L V P ++V+ A + + L ++++ +D+ Sbjct: 54 ----IEPVCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSF 104 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 VNL+ V+Q A+ L++ G G+I+N+SS + + Y ++K + LT+ A Sbjct: 105 EVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMA 164 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 ELG H IR N+V P + T M Q + IP+G + E V + + FL S Sbjct: 165 LELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLS 224 Query: 243 EDSGYITGTSVEVTGGLF 260 + SG TG+++ V GG + Sbjct: 225 DRSGMTTGSTLPVEGGFW 242 >1AHH-A nrPDB Length = 255 Score = 216 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 70/252 (27%), Positives = 125/252 (49%), Gaps = 11/252 (4%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL A++TGAG+GIG+ +++ A GA+V D++ AA V + G G Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-------G 60 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A + D++ + L + + + ++V+ AG + M D+ + +N Sbjct: 61 QAFACRCDITSEQELSALADFAISKLGK-VDILVNNAGGGGPKPF-DMPMADFRRAYELN 118 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 + F ++Q A + NG G I+ I+S+ + N+ T+YA+SKA L + A +L Sbjct: 119 VFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 Query: 188 GRHGIRCNSVLPGFIATPMTQK-VPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 G IR N + PG I T + + ++ K+ + P+ LG P+D+A+ FL S + Sbjct: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 Query: 247 YITGTSVEVTGG 258 +++G + V+GG Sbjct: 238 WVSGQILTVSGG 249 >3R3S-A nrPDB Length = 294 Score = 216 bits (550), Expect = 8e-57, Method: Composition-based stats. Identities = 76/260 (29%), Positives = 119/260 (45%), Gaps = 14/260 (5%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL--DRAAAQETVRLLGGPGSKEG 63 RL+ ALVTG SGIGRA ++ A EGA VA L + AQ+ L+ G K Sbjct: 44 SGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRK-- 101 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 D+S+ AR L+ + + + + T + ++ + + + Sbjct: 102 -----AVLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQT 156 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 AVN+ F +TQ A L SII SSI + +YAA+KA ++ ++ Sbjct: 157 FAVNVFALFWITQEAIPLLPK---GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGL 213 Query: 184 ARELGRHGIRCNSVLPGFIATPM--TQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A+++ GIR N V PG I T + + Q + + + PM G P ++A V +LA Sbjct: 214 AKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLA 273 Query: 242 SEDSGYITGTSVEVTGGLFM 261 S++S Y+T V GG + Sbjct: 274 SQESSYVTAEVHGVCGGEHL 293 >1O5I-A nrPDB Length = 249 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 111/256 (43%), Gaps = 25/256 (9%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 ++ +R LV A GIGRAV+ L+ EGA V C + + Sbjct: 13 MELGIRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLK--------------- 57 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 R H D+ + L E+V+ ++V AG + F ++ +D+ + I Sbjct: 58 -RSGHRYVVCDLR--KDLDLLFEKVKE-----VDILVLNAGGPKAGFFDELTNEDFKEAI 109 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 + + A+ G G I+ I+S +++ + G +T + Sbjct: 110 DSLFLNMIKIVRNYLPAMKEKGW-GRIVAITSFSVISPIENLYTSNSARMALTGFLKTLS 168 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 E+ +GI N V PG+ T +++ ++ ++ IPM + PE++A VVAFL SE Sbjct: 169 FEVAPYGITVNCVAPGWTETERVKELLSEEKKKQVESQIPMRRMAKPEEIASVVAFLCSE 228 Query: 244 DSGYITGTSVEVTGGL 259 + Y+TG ++ V GGL Sbjct: 229 KASYLTGQTIVVDGGL 244 >3UF0-A nrPDB Length = 273 Score = 213 bits (544), Expect = 5e-56, Method: Composition-based stats. Identities = 80/254 (31%), Positives = 126/254 (49%), Gaps = 13/254 (5%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L A+VTGAGSGIGRA++ A GA V A +E + G G+ Sbjct: 29 LAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-DGVKEVADEIADGG-------GS 80 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A AD+++ A + E++ A R V+V+ AGI +S W +V+ VNL Sbjct: 81 AEAVVADLADLEGAANVAEELAAT--RRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNL 138 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 ++++++ A++++G G I+ I+S++ G YAASK V+GLT+ A E Sbjct: 139 DAAWVLSRSFGTAMLAHGS-GRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWA 197 Query: 189 RHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 G+ N++ PG++ T T + + +IT IP G PED+ FLAS+ + Sbjct: 198 GRGVGVNALAPGYVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDAAS 257 Query: 247 YITGTSVEVTGGLF 260 Y+ G + V GG Sbjct: 258 YVHGQVLAVDGGWL 271 >2HSD-A nrPDB Length = 253 Score = 213 bits (544), Expect = 5e-56, Method: Composition-based stats. Identities = 81/253 (32%), Positives = 119/253 (47%), Gaps = 12/253 (4%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 N L ++TG G+G + + GA V D+ T R LG + Sbjct: 1 NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQ---- 56 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 DV+ + ++ + F +V+ AGI+ FL S + + KV+ + Sbjct: 57 ------HLDVTIEEDWQRVVAYAREEFGS-VDGLVNNAGISTGMFLETESVERFRKVVEI 109 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 NL G F+ + A+ G GSI+NISS G +G ++Y ASK GV GL++ AA E Sbjct: 110 NLTGVFIGMKTVIPAMKDAG-GGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVE 168 Query: 187 LGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 LG IR NSV PG TPMT + + + PMG +G+P ++A V L S+ S Sbjct: 169 LGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSS 228 Query: 247 YITGTSVEVTGGL 259 Y+TG + V GG Sbjct: 229 YVTGAELAVDGGW 241 >2B4Q-A nrPDB Length = 276 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 115/267 (43%), Gaps = 17/267 (6%) Query: 3 SQLQN--RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 S + L +ALVTG GIG+ ++ L GA V C D A +T L G Sbjct: 19 SHMHPYFSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGD 78 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 + A AD+S AR L + + +R ++V+ AG + L W Sbjct: 79 CQ--------AIPADLSSEAGARRLAQALGELSARL-DILVNNAGTSWGAALESYPVSGW 129 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCR---GSIINISSIVGKVGNVGQT-NYAASKAGV 176 +KV+ +N+ F Q L + +INI S+ G Q Y SKA + Sbjct: 130 EKVMQLNVTSVFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAAL 189 Query: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVA 234 L++ A+EL I N + PG + MT+ + + ++ + IPMG G PE++A Sbjct: 190 HQLSRMLAKELVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMA 249 Query: 235 DVVAFLASEDSGYITGTSVEVTGGLFM 261 + LA Y+TG + + GG + Sbjct: 250 ALAISLAGTAGAYMTGNVIPIDGGFHL 276 >1DOH-A nrPDB Length = 283 Score = 213 bits (542), Expect = 9e-56, Method: Composition-based stats. Identities = 73/268 (27%), Positives = 121/268 (45%), Gaps = 26/268 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDR-AAAQETVRLLGGPGSKEGPPRG 67 L +ALVTGAG GIGR +++ L G V + +A+E V + GS Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGS------- 79 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + A +A+V + E+ F + +V S +G+ + ++ +++D+V +N Sbjct: 80 DAACVKANVGVVEDIVRMFEEAVKIFGKL-DIVCSNSGVVSFGHVKDVTPEEFDRVFTIN 138 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARE 186 +G F V + A + L G +I + SI G+ Y+ SK + + A + Sbjct: 139 TRGQFFVAREAYKHLE---IGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAID 195 Query: 187 LGRHGIRCNSVLPGFIATPMT-----------QKVPQKVVDKITEMI--PMGHLGDPEDV 233 + I N V PG I T M + + + VD+ + P+ +G P D+ Sbjct: 196 MADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDI 255 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGLFM 261 A VV FLAS D G++TG + + GG M Sbjct: 256 ARVVCFLASNDGGWVTGKVIGIDGGACM 283 >5B1Y-A nrPDB Length = 270 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 83/256 (32%), Positives = 125/256 (48%), Gaps = 11/256 (4%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + + + ALVTG GIGRA +R A EG +V RA E Sbjct: 19 SHMETTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAE-----EARRLGS 73 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 + DV + + + +V +V+V+ AG+ Q + S +W++ + V Sbjct: 74 PEAYTVRVDVGDPDSVTEMSSRVGELIPHL-NVLVNAAGVLQLGGIEETSISEWEETLRV 132 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNV-GQTNYAASKAGVIGLTQTAAR 185 NL G +LVT+ L SI+N++SI G+ GNV Y+ASKAGVIGLT+ A Sbjct: 133 NLTGVYLVTKLLLPLLRKAKW-ASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAV 191 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 +L +GIR N+V P F+ T MT+ + ++I + P+ + PEDVA+ + FLA Sbjct: 192 QLAGYGIRVNAVAPSFVETDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADP 251 Query: 244 -DSGYITGTSVEVTGG 258 S ITG + + G Sbjct: 252 RRSRGITGHVLSINAG 267 >1CYD-A nrPDB Length = 244 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 117/258 (45%), Gaps = 18/258 (6%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 ++ ALVTGAG GIGR L GA V A + + G Sbjct: 1 MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG------- 53 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 D+ + A L + P ++V+ A + + L ++++ +D+ Sbjct: 54 ----IEPVCVDLGDWDATEKALGGI-----GPVDLLVNNAALVIMQPFLEVTKEAFDRSF 104 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 +VNL+ F V+Q A+ +++ G GSI+N+SS+V V Y+++K + LT+ A Sbjct: 105 SVNLRSVFQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMA 164 Query: 185 RELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 ELG H IR NSV P + T M +KV + K+ E P+ + EDV + + FL S Sbjct: 165 MELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLS 224 Query: 243 EDSGYITGTSVEVTGGLF 260 + S +G + V G Sbjct: 225 DRSASTSGGGILVDAGYL 242 >3OIC-A nrPDB Length = 258 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 70/252 (27%), Positives = 114/252 (45%), Gaps = 12/252 (4%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACD-LDRAAAQETVRLLGGPGSKEGPPRGN 68 ++ ALVTG+ G+G+A ++RLA G + + AA ET + G K Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVK------- 55 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 +A+V + + + +Q+ F R V V+ A ++ + E WD + +N Sbjct: 56 VLVVKANVGQPAKIKEMFQQIDETFGRL-DVFVNNAASGVLRPVMELEETHWDWTMNINA 114 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 K Q AA+ + NG G I++ISS+ T SKA + LT+ A EL Sbjct: 115 KALLFCAQEAAKLMEKNG-GGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELS 173 Query: 189 RHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 I N+V G I T + P + +++ + P G + + +D+ D V FL S + Sbjct: 174 PKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKAD 233 Query: 247 YITGTSVEVTGG 258 I G ++ V GG Sbjct: 234 MIRGQTIIVDGG 245 >5O3Z-A nrPDB Length = 263 Score = 210 bits (535), Expect = 6e-55, Method: Composition-based stats. Identities = 77/262 (29%), Positives = 129/262 (49%), Gaps = 18/262 (6%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +A+V G G +G + LA G VA DL+ + A + G Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTIN-----SRYGAGRAYG 61 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 F+ D ++ + L V F R ++V AG+ + + D+D + VNL G Sbjct: 62 FKVDATDEASVEALARAVDETFGRA-DLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGY 120 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHG 191 FL ++ ++ ++ +G +G II I+S GKVG+ + Y+A+K G +GLTQ+ A +L +G Sbjct: 121 FLCSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYG 180 Query: 192 IRCNSVLPG-FIATPMTQKV-----------PQKVVDKITEMIPMGHLGDPEDVADVVAF 239 I +S++ G + +PM Q + P++V + +P+ D +DV +V+ F Sbjct: 181 ITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLF 240 Query: 240 LASEDSGYITGTSVEVTGGLFM 261 AS+ + Y TG S+ VTGG M Sbjct: 241 YASDKAAYCTGQSINVTGGQVM 262 >3GDF-A nrPDB Length = 267 Score = 210 bits (534), Expect = 7e-55, Method: Composition-based stats. Identities = 78/259 (30%), Positives = 123/259 (47%), Gaps = 14/259 (5%) Query: 6 QNRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRA-AAQETVRLLGGPGSKE 62 Q L+ + +VTGA G+G + A GA VA RA A+E V+ L Sbjct: 15 QLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKT---- 70 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 A++ V + L++ V A F + + + + AG T D +L S + W+ Sbjct: 71 --YGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFI-ANAGATADSGILDGSVEAWNH 127 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNV--GQTNYAASKAGVIGLT 180 V+ V+L GTF +A G GS++ +S+ G + N QT+Y +KAG I + Sbjct: 128 VVQVDLNGTFHCAKAVGHHFKERGT-GSLVITASMSGHIANFPQEQTSYNVAKAGCIHMA 186 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 ++ A E R R NS+ PG+I T ++ VP++ MIPMG G +++ + Sbjct: 187 RSLANEW-RDFARVNSISPGYIDTGLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYF 245 Query: 241 ASEDSGYITGTSVEVTGGL 259 AS+ S Y TG + + GG Sbjct: 246 ASDASTYTTGADLLIDGGY 264 >1H5Q-A nrPDB Length = 265 Score = 208 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 72/268 (26%), Positives = 119/268 (44%), Gaps = 14/268 (5%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 MA + +VTG GIG A + +A GA VA A A E +G Sbjct: 4 MAPGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKE-- 61 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 A+Q DVS ++Q+ A P S +++ AG++ + ++ +D+ Sbjct: 62 ----FGVKTKAYQCDVSNTDIVTKTIQQIDADLG-PISGLIANAGVSVVKPATELTHEDF 116 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-------GNVGQTNYAASK 173 V VN+ G F +A A+ + +GSI+ SS+ ++ G++ Q Y +SK Sbjct: 117 AFVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSK 176 Query: 174 AGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDV 233 A L + A E GIR N++ PG++ T T + +K+ D IP+ PE++ Sbjct: 177 AACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPLNRFAQPEEM 236 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGLFM 261 L S+ + Y+TG + GG + Sbjct: 237 TGQAILLLSDHATYMTGGEYFIDGGQLI 264 >4AVY-A nrPDB Length = 242 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 71/252 (28%), Positives = 117/252 (46%), Gaps = 24/252 (9%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 LVTG SGIG A++++ A GA V A LD P Sbjct: 11 GQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGV-------------HAPRHPRIR 57 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 + D+++++ + L E + V+V+ AGI++D +++V+ +NL Sbjct: 58 REELDITDSQRLQRLFEALPR-----LDVLVNNAGISRDR--EEYDLATFERVLRLNLSA 110 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 L +Q A L G GSI+NI+S+ G+ + Y+ASK ++ LT++ A E Sbjct: 111 AMLASQLARPLLAQRG--GSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAE 168 Query: 191 GIRCNSVLPGFIATPMTQKVPQKVVD--KITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 IR N++ PG+I TP+ + V +I + P+ G+ +VA AFL + ++ Sbjct: 169 RIRVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFV 228 Query: 249 TGTSVEVTGGLF 260 TG + V GG Sbjct: 229 TGAVLAVDGGYL 240 >1HXH-A nrPDB Length = 253 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 82/258 (31%), Positives = 124/258 (48%), Gaps = 20/258 (7%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 NRL+ +ALVTG SG+G V L GEGA VA D++ AA Q+ LG Sbjct: 1 TNRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGE-------- 52 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + DVS ++ VQ +V+V+ AGI + +D+ +++ Sbjct: 53 --RSMFVRHDVSSEADWTLVMAAVQRRLGTL-NVLVNNAGILLPGDMETGRLEDFSRLLK 109 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 +N + F+ Q A+ G GSIIN++S+ + Y+ASKA V LT+ AA Sbjct: 110 INTESVFIGCQQGIAAMKETG--GSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAAL 167 Query: 186 ELGRHG--IRCNSVLPGFIATPMTQ-KVPQKVVDKITEMIP----MGHLGDPEDVADVVA 238 + G IR NS+ P I TPM Q +P+ V ++ P G PE +A +V Sbjct: 168 SCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVL 227 Query: 239 FLASEDSGYITGTSVEVT 256 FLAS++S ++G+ + Sbjct: 228 FLASDESSVMSGSELHAD 245 >4TRR-A nrPDB Length = 269 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 76/268 (28%), Positives = 130/268 (48%), Gaps = 20/268 (7%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 + L A+VTGA SGIG+ +++ LA GA VA DL++ A + G Sbjct: 9 MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAG------ 62 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 G DV+ A +++V F ++VS AGI + + S DW K+ A Sbjct: 63 -GKAIGVAMDVTNEEAVNTGIDKVAEAFGS-VDILVSNAGIQIVNPIENYSFADWKKMQA 120 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 +++ G FL T+AA + + + G +I + S+ + ++ Y +K G++GL + A+ Sbjct: 121 IHVDGAFLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAK 180 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKVV-------DKITEMIPMGH-----LGDPEDV 233 E +H +R + V PGF+ TP+ K + +++ + + +G+ +DV Sbjct: 181 EGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDV 240 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGLFM 261 A V FL++ S +TG S V+ G FM Sbjct: 241 AQTVLFLSAFPSAALTGQSFIVSHGWFM 268 >4FC7-A nrPDB Length = 277 Score = 203 bits (518), Expect = 4e-53, Method: Composition-based stats. Identities = 66/256 (25%), Positives = 112/256 (43%), Gaps = 11/256 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 LR +A +TG GSGIG ++ G R L G + P Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP--- 81 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 DV A ++Q F R ++++CA +S + + V+ ++ Sbjct: 82 ---LSMDVRAPPAVMAAVDQALKEFGRI-DILINCAAGNFLCPAGALSFNAFKTVMDIDT 137 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 GTF V++ + + G I+NI++ +G G Q + ++KA V +T+ A E G Sbjct: 138 SGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 196 Query: 189 RHGIRCNSVLPGFIA-TPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 IR NS+ PG I+ T +++ PQ + P+ LG+ ++A V +LAS + Sbjct: 197 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 256 Query: 246 GYITGTSVEVTGGLFM 261 Y+TG + GG ++ Sbjct: 257 SYVTGAVLVADGGAWL 272 >2O23-A nrPDB Length = 265 Score = 203 bits (517), Expect = 7e-53, Method: Composition-based stats. Identities = 82/265 (30%), Positives = 132/265 (49%), Gaps = 25/265 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 ++ +A++TG SG+G A + RL G+GA+ DL + + + LG N Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN----------N 59 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHM------SEDDWDK 122 ADV+ + + L + F R V V+CAGI ++ + +D+ + Sbjct: 60 CVFAPADVTSEKDVQTALALAKGKFGR-VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQR 118 Query: 123 VIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGVI 177 V+ VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G++ Sbjct: 119 VLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 178 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVADV 236 G+T AR+L GIR ++ PG TP+ +P+KV + + +P LGDP + A + Sbjct: 179 GMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHL 238 Query: 237 VAFLASEDSGYITGTSVEVTGGLFM 261 V A ++ ++ G + + G + M Sbjct: 239 VQ--AIIENPFLNGEVIRLDGAIRM 261 >2AG5-A nrPDB Length = 246 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 74/263 (28%), Positives = 127/263 (48%), Gaps = 25/263 (9%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 RL + ++T A GIG+A ++ A EGA V A D++ + QE + Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY----------- 49 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 DV++ + +V+ V+ + AG +L E DWD + Sbjct: 50 -PGIQTRVLDVTKKKQIDQFANEVER-----LDVLFNVAGFVHHGTVLDCEEKDWDFSMN 103 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-GNVGQTNYAASKAGVIGLTQTAA 184 +N++ +L+ +A +++ G+IIN+SS+ V G V + Y+ +KA VIGLT++ A Sbjct: 104 LNVRSMYLMIKAFLPKMLAQ-KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA 162 Query: 185 RELGRHGIRCNSVLPGFIATPMTQK------VPQKVVDKITEMIPMGHLGDPEDVADVVA 238 + + GIRCN V PG + TP Q+ P++ + + G E++A + Sbjct: 163 ADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCV 222 Query: 239 FLASEDSGYITGTSVEVTGGLFM 261 +LAS++S Y+TG V + GG + Sbjct: 223 YLASDESAYVTGNPVIIDGGWSL 245 >4RGB-A nrPDB Length = 294 Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats. Identities = 60/272 (22%), Positives = 106/272 (38%), Gaps = 19/272 (6%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRA-----AAQETVRLLGGPGS 60 L + +TGA G GR+ +V A +GA + D+ T L Sbjct: 20 MGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETAR 79 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 +ADV + + + + F V++ AG+ + + Sbjct: 80 LVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHI-DTVIANAGVVLTNPDERDASEAL 138 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV----GNVGQTNYAASKAGV 176 + + L G + Q A + G G++I SS++ + G G Y SK + Sbjct: 139 RLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAI 198 Query: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP---------QKVVDKITEMIPMGHL 227 GL ++ A L IR N V P +TPM + P +V+ ++ +P + Sbjct: 199 TGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPM 258 Query: 228 GDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 +P DV++ + FL S+ TG+ ++V G+ Sbjct: 259 IEPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >1E3W-A nrPDB Length = 261 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 82/265 (30%), Positives = 131/265 (49%), Gaps = 25/265 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 ++ +A++TG SG+G + + RL G+GAT D+ + + + LG GN Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG----------GN 57 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHM------SEDDWDK 122 A+V+ + + L + F R V V+CAGI H + +D+ + Sbjct: 58 CIFAPANVTSEKEVQAALTLAKEKFGRI-DVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 Query: 123 VIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGVI 177 VI VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G++ Sbjct: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVADV 236 G+T AR+L GIR ++ PG ATP+ +P V + + +P LGDP + A + Sbjct: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHL 236 Query: 237 VAFLASEDSGYITGTSVEVTGGLFM 261 V + ++ ++ G + + G + M Sbjct: 237 VQMVI--ENPFLNGEVIRLDGAIRM 259 >2GDZ-A nrPDB Length = 267 Score = 196 bits (498), Expect = 9e-51, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 28/263 (10%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + + + +ALVTGA GIGRA + L +GA VA D + A + L E Sbjct: 1 MAHMVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL-----HEQF 55 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 Q DV++ + R +V F R ++V+ AG+ E +W+K + Sbjct: 56 EPQKTLFIQCDVADQQQLRDTFRKVVDHFGRL-DILVNNAGVNN--------EKNWEKTL 106 Query: 125 AVNLKGTFLVTQAAAQALVSN--GCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 +NL T + G G IIN+SS+ G + Q Y ASK G++G T++ Sbjct: 107 QINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 166 Query: 183 --AARELGRHGIRCNSVLPGFIATPMTQKVPQ--------KVVDKITEMIPMGHLGDPED 232 A L G+R N++ PGF+ T + + + + + D I +MI + DP Sbjct: 167 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPL 226 Query: 233 VADVVAFLASEDSGYITGTSVEV 255 +A+ + L +D+ + G +++ Sbjct: 227 IANGLITLIEDDA--LNGAIMKI 247 >2FWM-X nrPDB Length = 250 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 70/260 (26%), Positives = 113/260 (43%), Gaps = 29/260 (11%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 VTGAG GIG A ++ GA V D+A QE Sbjct: 5 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQY---------------P 47 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 A DV++A + +++ A R +V+ AGI + +S++DW + AVN+ Sbjct: 48 FATEVMDVADAAQVAQVCQRLLAETERL-DALVNAAGILRMGATDQLSKEDWQQTFAVNV 106 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 G F + Q G+I+ ++S +G + Y ASKA + L + EL Sbjct: 107 GGAFNLFQQTMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELA 165 Query: 189 RHGIRCNSVLPGFIATPMTQKVP----------QKVVDKITEMIPMGHLGDPEDVADVVA 238 G+RCN V PG T M + + + ++ IP+G + P+++A+ + Sbjct: 166 GSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTIL 225 Query: 239 FLASEDSGYITGTSVEVTGG 258 FLAS+ + +IT + V GG Sbjct: 226 FLASDLASHITLQDIVVDGG 245 >4EGF-A nrPDB Length = 266 Score = 193 bits (491), Expect = 6e-50, Method: Composition-based stats. Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 9/256 (3%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 RL AL+TGA GIG ++ A GA + D + R LG Sbjct: 17 RLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGE------QFGT 70 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + D++E A L + F V+V+ AGI+ + ++ +D IAVN Sbjct: 71 DVHTVAIDLAEPDAPAELARRAAEAFGGL-DVLVNNAGISHPQPVVDTDPQLFDATIAVN 129 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 L+ L+ A +A+V+ G G+II ++S Y SKAG++ T+ AREL Sbjct: 130 LRAPALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLAREL 189 Query: 188 GRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 G HGIR NSV P + T M Q+V + + IP+G P +V+D V +LAS+ + Sbjct: 190 GPHGIRANSVCPTVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAA 249 Query: 246 GYITGTSVEVTGGLFM 261 I G + V GG M Sbjct: 250 SMINGVDIPVDGGYTM 265 >5JS6-A nrPDB Length = 274 Score = 193 bits (491), Expect = 7e-50, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 107/240 (44%), Gaps = 20/240 (8%) Query: 28 SVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLE 87 GA V CD D + + + L G DV++ + L+ Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPGA-----------VFILCDVTQEDDVKTLVS 76 Query: 88 QVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGC 147 + F R VV + + S + +++ +NL GT+ +T+ A L Sbjct: 77 ETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK--S 134 Query: 148 RGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMT 207 +G++INISS+VG +G Y A+K V +T+ A + +G+R N + PG I TP+ Sbjct: 135 QGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLW 194 Query: 208 QKV------PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 +++ P+ + + P+G +G P +V FLAS ++ + TG + VTGG + Sbjct: 195 EELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAEL 253 >3UN1-A nrPDB Length = 260 Score = 193 bits (491), Expect = 7e-50, Method: Composition-based stats. Identities = 71/258 (27%), Positives = 119/258 (46%), Gaps = 25/258 (9%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 Q R + + ++TGA GIG + V A + Sbjct: 20 FQSMMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRS----------------IK 63 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 + D+S+ A ++ + F R S +V+ AG+ + + M+++D+D Sbjct: 64 PSADPDIHTVAGDISKPETADRIVREGIERFGRIDS-LVNNAGVFLAKPFVEMTQEDYDH 122 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAAS--KAGVIGLT 180 + VN+ G F +TQ AA ++ G G I++I++ + VG + AS K G+ +T Sbjct: 123 NLGVNVAGFFHITQRAAAEMLKQGS-GHIVSITTSLVDQPMVGMPSALASLTKGGLNAVT 181 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 ++ A E R G+R N+V PG I TPM P + + + P+G +G+ DV D V +L Sbjct: 182 RSLAMEFSRSGVRVNAVSPGVIKTPMH---PAETHSTLAGLHPVGRMGEIRDVVDAVLYL 238 Query: 241 ASEDSGYITGTSVEVTGG 258 E +G+ITG + V GG Sbjct: 239 --EHAGFITGEILHVDGG 254 >3V8B-A nrPDB Length = 283 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 91/263 (34%), Positives = 133/263 (50%), Gaps = 21/263 (7%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +AL+TGAGSGIGRA ++ LA +G TV A R +E + G G G Sbjct: 28 SPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAG-------GQAI 80 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD-EFLLHMSEDDWDKVIAVNLK 129 A +ADVS+ R + + F +VV+ AGI + + +WD+ IAVNL+ Sbjct: 81 ALEADVSDELQMRNAVRDLVLKFGHL-DIVVANAGINGVWAPIDDLKPFEWDETIAVNLR 139 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVGKVGN--VGQTNYAASKAGVIGLTQTAAREL 187 GTFL L G G+I+ +SSI G G T Y A+KA + + Q A EL Sbjct: 140 GTFLTLHLTVPYLKQRG-GGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALEL 198 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT-------EMIPM--GHLGDPEDVADVVA 238 G+H IR N+V PG I T ++ + ++ +P+ G G EDVA+++ Sbjct: 199 GKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIR 258 Query: 239 FLASEDSGYITGTSVEVTGGLFM 261 FL SE + ++TG+ V + GG + Sbjct: 259 FLVSERARHVTGSPVWIDGGQGL 281 >3U4C-A nrPDB Length = 281 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 57/263 (21%), Positives = 105/263 (39%), Gaps = 18/263 (6%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + + A V GA GIG+A++++LA + ++ + + + P Sbjct: 19 SHMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDI-----LAKHPE 73 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 + D+S+ + +++++ R ++ + G D + + +D Sbjct: 74 ASVIVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDT-FDNCNIEDMTATFTQ 132 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 + A+ + G IINI + K + A +I ++ + + Sbjct: 133 KTVAYIDAIKRASSLM-KQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQ 191 Query: 187 LGRHGIRCNSVLPGFIATPMTQKV-----------PQKVVDKITEMIPMGHLGDPEDVAD 235 L H I N + PGFIAT + QK ++I IPM +G E+ A Sbjct: 192 LAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAA 251 Query: 236 VVAFLASEDSGYITGTSVEVTGG 258 + AFLASE++ YITG + GG Sbjct: 252 LAAFLASEEASYITGQQISADGG 274 >3PXX-A nrPDB Length = 287 Score = 190 bits (483), Expect = 6e-49, Method: Composition-based stats. Identities = 71/287 (24%), Positives = 104/287 (36%), Gaps = 37/287 (12%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-----DRAAAQETVRLLGGPGS 60 R++ + LVTG G GR+ +V+LA EGA + D+ T R L G Sbjct: 5 MGRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGL 64 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW 120 + + DV + A L A F + VVV+ AGI H+ + Sbjct: 65 EVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKL-DVVVANAGICPLGA--HLPVQAF 121 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV-----------GNVGQTNY 169 V+ G AA L SII S+ G + G Y Sbjct: 122 ADAFDVDFVGVINTVHAALPYLT---SGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGY 178 Query: 170 AASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP-----------QKVVDKI 218 + +K V T A +L IR N + P + T M P D + Sbjct: 179 SYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADAL 238 Query: 219 TEMIPMGHLGDP----EDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 M + P D+++ V FLAS++S Y+TG +V G + Sbjct: 239 LAFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >2X9N-A nrPDB Length = 288 Score = 189 bits (481), Expect = 8e-49, Method: Composition-based stats. Identities = 73/275 (26%), Positives = 116/275 (42%), Gaps = 28/275 (10%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + + + A+VTGA IGRA++V+L G V + A A + Sbjct: 19 SHMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAA-----VSLADELNKERS 73 Query: 67 GNHAAFQADVSEARAARCLLEQVQ----ACFSRPPSVVVSCAGITQDEFLLHMSEDD--- 119 QAD++ + E++ F R V+V+ A L+ +D Sbjct: 74 NTAVVCQADLTNSNVLPASCEEIINSCFRAFGR-CDVLVNNASAFYPTPLVQGDHEDNSN 132 Query: 120 -------WDKVIAVNLKGTFLVTQAAAQALVSNG-----CRGSIINISSIVGKVGNVGQT 167 ++I N FL+T + AQ SI+N+ + + + Sbjct: 133 GKTVETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFS 192 Query: 168 NYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHL 227 Y K ++GLTQ+AA EL +GIR N V PG P+ + ++ DK +P+G Sbjct: 193 LYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPV--AMGEEEKDKWRRKVPLGRR 250 Query: 228 -GDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 E +AD V FL S + YITG+ ++V GGL + Sbjct: 251 EASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >5JY1-A nrPDB Length = 274 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 73/261 (27%), Positives = 120/261 (45%), Gaps = 15/261 (5%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 L +ALVTGAG GIGR V+ EGA V +++ + ++ + + G Sbjct: 9 MGLLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMG------ 62 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW-DKVI 124 G + DV+ + + F ++V+ A + LL D+ ++ + Sbjct: 63 -GRSLFVKTDVTSKASIEAAVRSAVEQFGSL-DILVNNAFVPTPNVLLEEKTDEMLEQTL 120 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 +L T+ +AA + G I+N SI + G +Y +KAG++GLT++AA Sbjct: 121 TTSLWATWWAMRAAFVPMRERRW-GRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAA 179 Query: 185 RELGRHGIRCNSVLP---GFIATPMTQKVPQKVVDKITEMIPMGHLGDPE-DVADVVAFL 240 E GR I N++ P G + K P + ++ P+G GDPE D+ F Sbjct: 180 SEWGRFNITVNAIAPTAMGATFFELAAKNP-EFAERSAAARPLGRSGDPEQDIGPAAVFF 238 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 ASE S ++TG ++ V GGL + Sbjct: 239 ASEMSRFVTGETLHVDGGLHL 259 >3OML-A nrPDB Length = 613 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 117/245 (47%), Gaps = 17/245 (6%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 R +A+VTGAG+G+GR ++ A GA V DL + + + + Sbjct: 16 RYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A AD + ++E F R ++V+ AGI +D L+ SE DW+ V V+ Sbjct: 76 GGEAV-ADYNSVIDGAKVIETAIKAFGR-VDILVNNAGILRDRSLVKTSEQDWNLVNDVH 133 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 LKG+F TQAA + G II SS G GN GQ NY A+K G+IGL T A E Sbjct: 134 LKGSFKCTQAAFPYMKKQNY-GRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEG 192 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL----ASE 243 R+ + CN ++P A+ MT+ + ++ + P+ +A VVA+L + Sbjct: 193 ARNNVLCNVIVPTA-ASRMTEGILPDILFNELK---------PKLIAPVVAYLCHESCED 242 Query: 244 DSGYI 248 + YI Sbjct: 243 NGSYI 247 >3ZV3-A nrPDB Length = 281 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 115/267 (43%), Gaps = 28/267 (10%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L +AL+TG SG+GRA+ R EGA VA D +E E G Sbjct: 2 KLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLREL----------EVAHGG 51 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSED----DWDKV 123 N DV + + E+ A F + +++ + L + ED +D + Sbjct: 52 NAVGVVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDI 111 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 VN+KG +A ALVS RGS++ S G N G Y A+K V+GL + Sbjct: 112 FHVNVKGYIHAVKACLPALVS--SRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQM 169 Query: 184 ARELGRHGIRCNSVLPGFIATPM----TQKVPQK------VVDKITEMIPMGHLGDPEDV 233 A EL H +R N V PG + T + + + ++ + D + ++P+G + E+ Sbjct: 170 AFELAPH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEY 228 Query: 234 ADVVAFLASE-DSGYITGTSVEVTGGL 259 F A+ DS TG + GG+ Sbjct: 229 TGAYVFFATRGDSLPATGALLNYDGGM 255 >4CR6-A nrPDB Length = 271 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 79/260 (30%), Positives = 117/260 (45%), Gaps = 19/260 (7%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 RL A+VTGA GIGRA EGA+V A DL A G Sbjct: 11 GRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGA--------- 61 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 D+++ A + A +V A L +S+ DWD+ + V Sbjct: 62 ---IPIACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDV 118 Query: 127 NLKGTFLVTQAAAQALV-----SNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 N+ GTFL +A A+A+V +G II I S+ + Y A+K GV LT+ Sbjct: 119 NMTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTR 178 Query: 182 TAARELGRHGIRCNSVLPGFIAT--PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 A +L RHGI N + PG + T ++ +++ + + +G G PE+VA F Sbjct: 179 AMAVDLARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVF 238 Query: 240 LASEDSGYITGTSVEVTGGL 259 LA + S +ITG+++ + GGL Sbjct: 239 LAEDGSSFITGSTITIDGGL 258 >1BDB-A nrPDB Length = 277 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 111/267 (41%), Gaps = 28/267 (10%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +L+ L+TG SG+GRA+ R EGA VA D E E Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAEL----------ETDHGD 51 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSED----DWDKV 123 N DV + + A F + +++ + L+ + E+ +D+V Sbjct: 52 NVLGIVGDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEV 111 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 +N+KG +A ALV+ RG++I S G N G Y A+K ++GL + Sbjct: 112 FHINVKGYIHAVKACLPALVA--SRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVREL 169 Query: 184 ARELGRHGIRCNSVLPGFIATPM----TQKVPQK------VVDKITEMIPMGHLGDPEDV 233 A EL + +R N V G I + + + + K + D + ++P+G + + E+ Sbjct: 170 AFELAPY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEY 228 Query: 234 ADVVAFLASE-DSGYITGTSVEVTGGL 259 F A+ D+ TG + GGL Sbjct: 229 TGAYVFFATRGDAAPATGALLNYDGGL 255 >4DA9-A nrPDB Length = 280 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 78/261 (29%), Positives = 130/261 (49%), Gaps = 14/261 (5%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL-DRAAAQETVRLLGGPGSKEG 63 + + +A+VTG GIG ++ LA G +A + D + L G G++ Sbjct: 23 MMTQKARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGAR-- 80 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF--LLHMSEDDWD 121 +AD+++ + + ++ V A F R +V+ AGI L + +++D Sbjct: 81 -----VIFLRADLADLSSHQATVDAVVAEFGRIDC-LVNNAGIASIVRDDFLDLKPENFD 134 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGS--IINISSIVGKVGNVGQTNYAASKAGVIGL 179 ++ VNL+GT TQA +A++++ R S IINI+S+ + + + +Y SKAG+ Sbjct: 135 TIVGVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAF 194 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE-MIPMGHLGDPEDVADVVA 238 +Q A L GI V PG I + MT V K I ++PM G+PED+ ++VA Sbjct: 195 SQGLALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLVPMRRWGEPEDIGNIVA 254 Query: 239 FLASEDSGYITGTSVEVTGGL 259 LA G+ TG+ ++ GGL Sbjct: 255 GLAGGQFGFATGSVIQADGGL 275 >2QHX-A nrPDB Length = 328 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 107/288 (37%), Gaps = 47/288 (16%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACD-LDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +ALVTGA +GR+++ L EG V A A L + Sbjct: 47 PVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNAR------RPNSAI 100 Query: 71 AFQADVSEARA-----------------ARCLLEQVQACFSRPPSVVVSCAGITQDEFLL 113 QAD+S L+ + R V+V+ A LL Sbjct: 101 TVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGR-CDVLVNNASSFYPTPLL 159 Query: 114 HMSEDDWD--------------KVIAVNLKGTFLVTQAAAQAL-----VSNGCRGSIINI 154 ED + + N + + +A A + G SIIN+ Sbjct: 160 RNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINM 219 Query: 155 SSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKV 214 + +G T Y +K + GLT++AA EL IR N V PG + + +P V Sbjct: 220 VDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAV 277 Query: 215 VDKITEMIPMG-HLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 + +P+ +V+DVV FL S + YITGT V+V GG + Sbjct: 278 WEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2BFA-A nrPDB Length = 288 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 107/288 (37%), Gaps = 47/288 (16%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACD-LDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +ALVTGA +GR+++ L EG V A A L + Sbjct: 7 PVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNAR------RPNSAI 60 Query: 71 AFQADVSEARA-----------------ARCLLEQVQACFSRPPSVVVSCAGITQDEFLL 113 QAD+S L+ + R V+V+ A LL Sbjct: 61 TVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGR-CDVLVNNASSFYPTPLL 119 Query: 114 HMSEDDWD--------------KVIAVNLKGTFLVTQAAAQAL-----VSNGCRGSIINI 154 ED + + N + + +A A + G SIIN+ Sbjct: 120 RNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINM 179 Query: 155 SSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKV 214 + +G T Y +K + GLT++AA EL IR N V PG + + +P V Sbjct: 180 VDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAV 237 Query: 215 VDKITEMIPMG-HLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 + +P+ +V+DVV FL S + YITGT V+V GG + Sbjct: 238 WEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >1P33-A nrPDB Length = 289 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 72/294 (24%), Positives = 111/294 (37%), Gaps = 45/294 (15%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + + +ALVTGA +G +++ L EG TV AA T+ + Sbjct: 1 MTTSPTAPVALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLA-----ATLNAR 55 Query: 65 PRGNHAAFQADVSEARA-----------------ARCLLEQVQACFSRPPSVVVSCAGIT 107 + QAD+S L++ + R V+V+ A Sbjct: 56 RPNSAITVQADLSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGR-CDVLVNNASSF 114 Query: 108 QDEFLLHMS--------------EDDWDKVIAVNLKGTFLVTQAAAQALV-----SNGCR 148 LL E + N + + +A AQ + G Sbjct: 115 YPTPLLRKDAGEGGSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTS 174 Query: 149 GSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQ 208 SI+N+ + +G T Y +K + GLT++AA EL IR N V PG P Sbjct: 175 YSIVNMVDAMTSQPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--D 232 Query: 209 KVPQKVVDKITEMIPMG-HLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 +P V + +P+ E+V+DVV FL S + YITGT ++V GG + Sbjct: 233 DMPFSVQEDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >2BGM-A nrPDB Length = 278 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 65/240 (27%), Positives = 112/240 (46%), Gaps = 18/240 (7%) Query: 28 SVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLE 87 + GA V D+ Q+ +G P + DV++ R L++ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDV--------ISFVHCDVTKDEDVRNLVD 84 Query: 88 QVQACFSRPPSVVVSCAGITQDEF--LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSN 145 A + ++ G+ +L +D+ +V+ +N+ G FLV + AA+ ++ Sbjct: 85 TTIAKHGKL-DIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPA 143 Query: 146 GCRGSIINISSIVGKVGNVGQTN-YAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 204 +GSI+ +SI G ++ Y A+K V+GLT + ELG +GIR N V P +A+ Sbjct: 144 -KKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVAS 202 Query: 205 PMTQKVPQKVVDKITEMIPM-----GHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 P+ V ++ E+ G L EDVAD VA+LA ++S Y++G ++ + GG Sbjct: 203 PLLTDVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGY 262 >5IZ4-A nrPDB Length = 271 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 69/261 (26%), Positives = 121/261 (46%), Gaps = 18/261 (6%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 + ++TG+ SGIG A ++R A G +VA + D + + Sbjct: 15 PVCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAA----STVEALCRDAGAQTLI 70 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAG---ITQDEFLLHMSEDDWDKVIAVNL 128 F ADV + R ++ V + + R +++CAG + + + ++++V VNL Sbjct: 71 FDADVGKDADCRHAVDMVASRWQRI-DALINCAGTTRVIPHNAFDQIDDFEFERVYRVNL 129 Query: 129 KGTFLVTQAAAQALVSNG---CRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 G + +T+AA L + S++N+SS+ G G YAASK V LT + AR Sbjct: 130 IGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLAR 189 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQK-----VVDKITEMIPMGHLGDPEDVADVVAFL 240 L H IR N++ PG + + +V V+ ++TE P+ + P ++A++ FL Sbjct: 190 NLAPH-IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL 248 Query: 241 ASEDSGYITGTSVEVTGGLFM 261 + + ITG + GL + Sbjct: 249 -TAHAPAITGQVIAAENGLLL 268 >1W73-A nrPDB Length = 302 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 117/255 (45%), Gaps = 10/255 (3%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 N + +A +TG G+G+G+ ++ L+ GA + T + Sbjct: 22 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISS------QTG 75 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 A Q DV + + + ++ P ++V++ A +S + W + + Sbjct: 76 NKVHAIQCDVRDPDMVQNTVSELIKVAGHP-NIVINNAAGNFISPTERLSPNAWKTITDI 134 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE 186 L GT VT + L+ + ++I++I + G+ A++KAGV ++++ A E Sbjct: 135 VLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE 194 Query: 187 LGRHGIRCNSVLPGFIAT--PMTQKVPQKVVD-KITEMIPMGHLGDPEDVADVVAFLASE 243 G++G+R N + PG I T ++ P + ++ IP G LG E++A++ AFL S+ Sbjct: 195 WGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 254 Query: 244 DSGYITGTSVEVTGG 258 + +I G ++ GG Sbjct: 255 YASWINGAVIKFDGG 269 >2NWQ-A nrPDB Length = 272 Score = 168 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 53/254 (20%), Positives = 101/254 (39%), Gaps = 16/254 (6%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + + L +TGA SG G A + R A G ++ Q L Sbjct: 18 SHMSSTL-----FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSA----- 67 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDE-FLLHMSEDDWD 121 + DV + A ++ + F+ +++ AG+ DDWD Sbjct: 68 ---KTRVLPLTLDVRDRAAMSAAVDNLPEEFATLRG-LINNAGLALGTDPAQSCDLDDWD 123 Query: 122 KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 ++ N+KG T+ L+++G SI+N+ S+ GK G Y +KA V + Sbjct: 124 TMVDTNIKGLLYSTRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSL 183 Query: 182 TAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 +L G+R ++ PG + + + + H PED+A+ + ++ Sbjct: 184 NLRCDLQGTGVRVTNLEPGLCESEFSLVRFGGDQARYDKTYAGAHPIQPEDIAETIFWIM 243 Query: 242 SEDSGYITGTSVEV 255 ++ + ++ S+E+ Sbjct: 244 NQPA-HLNINSLEI 256 >2YW9-A nrPDB Length = 261 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 59/260 (22%), Positives = 98/260 (37%), Gaps = 18/260 (6%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L ALV G +G A++ +L GA VA L K Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSY--------QAERLRPEAEKLAEAL 57 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD---EFLLHMSEDDWDKV 123 G F+ADV++ L V+ F +V + A ++ + DW Sbjct: 58 GGALLFRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLA 117 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 + V+ V + A L G I+ ++ + A +KA + + Sbjct: 118 LEVSAYSLVAVARRAEPLLRE---GGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYL 174 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A ELG G+R N++ G + T + +P K+ D++ + P+ E+V ++ FL Sbjct: 175 AYELGPKGVRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLL 234 Query: 242 SEDSGYITGTSVEVTGGLFM 261 S + ITG V V G + Sbjct: 235 SPLASGITGEVVYVDAGYHI 254 >4GKB-A nrPDB Length = 258 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 69/262 (26%), Positives = 111/262 (42%), Gaps = 19/262 (7%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + L+ + +VTG SGIG A+S+RLA E A G Sbjct: 1 MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPD--------GAFLDALAQ 52 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 + ++ + R + Q A F R +V+ AG+ D L D + + Sbjct: 53 RQPRATYLPVELQDDAQCRDAVAQTIATFGRL-DGLVNNAGV-NDGIGLDAGRDAFVASL 110 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA 184 NL + + L + RG+I+NISS G + Y ASK + LT+ A Sbjct: 111 ERNLIHYYAMAHYCVPHLKA--TRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWA 168 Query: 185 RELGRHGIRCNSVLPGFIATPMTQ------KVPQKVVDKITEMIPMG-HLGDPEDVADVV 237 L HG+R N+V+P + TP+ + + P+ + +I +P+G P+++AD Sbjct: 169 VALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTA 228 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 FL S + + TG + V GG Sbjct: 229 VFLLSPRASHTTGEWLFVDGGY 250 >3PPI-A nrPDB Length = 281 Score = 164 bits (415), Expect = 4e-41, Method: Composition-based stats. Identities = 81/262 (30%), Positives = 122/262 (46%), Gaps = 24/262 (9%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + A A+V+G G+G A RL +G V DL + LG Sbjct: 26 KQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGN--------- 76 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLL--HMSEDD---WD 121 +V+ + +E R VV+ G + ++ S D + Sbjct: 77 -RAEFVSTNVTSEDSVLAAIEAAN-QLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFT 134 Query: 122 KVIAVNLKGTFLVTQAAAQAL-----VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGV 176 K I + L GT+ V + A ++ NG RG+++ +SI G G +GQT YAA+KAGV Sbjct: 135 KTIDLYLNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGV 194 Query: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVAD 235 IGLT AAR+L GIR N++ PG + TP+ + V ++ + K IP LG P++ AD Sbjct: 195 IGLTIAAARDLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFAD 254 Query: 236 VVAFLASEDSGYITGTSVEVTG 257 AFL + +GYI G + + G Sbjct: 255 AAAFLLT--NGYINGEVMRLDG 274 >3RKU-A nrPDB Length = 287 Score = 159 bits (404), Expect = 8e-40, Method: Composition-based stats. Identities = 51/243 (20%), Positives = 96/243 (39%), Gaps = 19/243 (7%) Query: 8 RLRSALALVTGAGSGIGRAVSVRLAGEG---ATVAACDLDRAAAQETVRLLGGPGSKEGP 64 RL L+TGA +GIG+A ++ + +E + + Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQE-----F 84 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAG-ITQDEFLLHMSEDDWDKV 123 P Q D+++A + +E + F ++V+ AG + + ++ +D V Sbjct: 85 PNAKVHVAQLDITQAEKIKPFIENLPQEFKDI-DILVNNAGKALGSDRVGQIATEDIQDV 143 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 N+ +TQA + G I+N+ SI G+ + Y ASK V T + Sbjct: 144 FDTNVTALINITQAVLPIFQAKNS-GDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSL 202 Query: 184 ARELGRHGIRCNSVLPGFIATPMT----QKVPQKVVDKITEMIPMGHLGDPEDVADVVAF 239 +EL IR + PG + T + + ++ + + P+ +DVAD++ + Sbjct: 203 RKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPL----MADDVADLIVY 258 Query: 240 LAS 242 S Sbjct: 259 ATS 261 >4HBG-A nrPDB Length = 286 Score = 159 bits (403), Expect = 9e-40, Method: Composition-based stats. Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 37/271 (13%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +A+VTGA GIG+A+ +L +G + + + + T G S R A Sbjct: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 Query: 72 FQ-------ADVSEARAARCLLEQ--VQACFSRPPS---------------VVVSCAGIT 107 D ++ ++ +S ++++CAG+T Sbjct: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 Query: 108 QDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVS----------NGCRGSIINISSI 157 Q+ + + ++ VN +T + ++ R +I+NISSI Sbjct: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 Query: 158 --VGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIA-TPMTQKVPQKV 214 GK+ G + Y+ASKA + T+ A E+ IRC ++ PG + T M Q +P + Sbjct: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 Query: 215 VDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 + + I P ++A+ V L S + Sbjct: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 >1A27-A nrPDB Length = 289 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 56/208 (26%), Positives = 93/208 (44%), Gaps = 8/208 (3%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 + L+TG SGIG ++VRLA + + + RL + PP G+ Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPP-GSLETL 62 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 Q DV ++++ E+V V+V AG+ L + ED V+ VN+ GT Sbjct: 63 QLDVRDSKSVAAARERVTE---GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 119 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 + QA + G G ++ S+ G +G Y ASK + GL ++ A L G+ Sbjct: 120 RMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 178 Query: 193 RCNSVLPGFIATPMTQKV---PQKVVDK 217 + + G + T +KV P++V+D+ Sbjct: 179 HLSLIECGPVHTAFMEKVLGSPEEVLDR 206 >2P91-A nrPDB Length = 285 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 52/264 (19%), Positives = 100/264 (37%), Gaps = 17/264 (6%) Query: 5 LQNRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 L AL+TG I ++ EGA +A L + Sbjct: 15 FMGLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATP--------KLEKRVREI 66 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF---LLHMSEDD 119 G+ + DVS + L + ++ + +V S A ++EF ++ S + Sbjct: 67 AKGFGSDLVVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREG 126 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + + +++ +T+ + G G+I+ +S + +KA + Sbjct: 127 FKIAMDISVYSLIALTRELLPLM--EGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALEST 184 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVV 237 + A ++ +HG R N++ G + T + +++ T++ P G EDV D Sbjct: 185 VRYLAYDIAKHGHRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTA 244 Query: 238 AFLASEDSGYITGTSVEVTGGLFM 261 FL S+ + ITG V V G + Sbjct: 245 VFLCSDWARAITGEVVHVDNGYHI 268 >4DRY-A nrPDB Length = 281 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 67/244 (27%), Positives = 107/244 (43%), Gaps = 10/244 (4%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 M +Q + +ALVTG G+G+GR ++ L+ EG +V +GG Sbjct: 23 MMAQGKGSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGR-- 80 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGI-TQDEFLLHMSEDD 119 A DV + L V+A F+R ++V+ AG L ++ + Sbjct: 81 ----TGNIVRAVVCDVGDPDQVAALFAAVRAEFARL-DLLVNNAGSNVPPVPLEEVTFEQ 135 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNG-CRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 W+ ++A NL G FL TQ A + + + G IIN SI + Y A+K + G Sbjct: 136 WNGIVAANLTGAFLCTQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITG 195 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVA 238 LT++ A + H I C + G AT MT ++ V+ E + E +A+ V Sbjct: 196 LTKSTALDGRMHDIACGQIDIGNAATDMTARMSTGVLQANGE-VAAEPTIPIEHIAEAVV 254 Query: 239 FLAS 242 ++AS Sbjct: 255 YMAS 258 >6CGE-A nrPDB Length = 328 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 56/208 (26%), Positives = 93/208 (44%), Gaps = 8/208 (3%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 + L+TG SGIG ++VRLA + + + RL + PP G+ Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPP-GSLETL 63 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 Q DV ++++ E+V V+V AG+ L + ED V+ VN+ GT Sbjct: 64 QLDVRDSKSVAAARERVTE---GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 + QA + G G ++ S+ G +G Y ASK + GL ++ A L G+ Sbjct: 121 RMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 Query: 193 RCNSVLPGFIATPMTQKV---PQKVVDK 217 + + G + T +KV P++V+D+ Sbjct: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDR 207 >5ILO-A nrPDB Length = 271 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 21/214 (9%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGA-TVAACDLDRAAAQETVRLLGGPGSKEGPP 65 R A+VTG GIG VS +L GA VA DL + +E V+L + P Sbjct: 11 TSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDL-QDNLEEFVKL------RAAHP 63 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + + DV+ + E++ F +VV+ AGI D+ D + + Sbjct: 64 TQSVMIIKMDVANKKGVEATYEEIAKTFGNI-DIVVNVAGIFNDK--------DVQRTLL 114 Query: 126 VNLKGTFLVTQAAAQALVSN--GCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 VNL G T +A + + G G ++N+SS+VG Y A+KAG+I T+ Sbjct: 115 VNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCL 174 Query: 184 ARE--LGRHGIRCNSVLPGFIATPMTQKVPQKVV 215 A E R GI+ +V PG T M +K++ Sbjct: 175 ANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKII 208 >3OIG-A nrPDB Length = 266 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 53/264 (20%), Positives = 95/264 (35%), Gaps = 16/264 (6%) Query: 5 LQNRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 + L +V G I ++ L GA + + L G Sbjct: 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTL---- 56 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 R + DV+ ++ + A ++E + + D Sbjct: 57 --DRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDG 114 Query: 123 -VIAVNLKGTFLVT--QAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 ++A N+ L +AA + GSI+ ++ + G++ +KA + Sbjct: 115 FLLAHNISSYSLTAVVKAARPMMTE---GGSIVTLTYLGGELVMPNYNVMGVAKASLDAS 171 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVV 237 + A +LG+ IR NS+ G I T + + ++ I E P+ PE+V D Sbjct: 172 VKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTA 231 Query: 238 AFLASEDSGYITGTSVEVTGGLFM 261 AFL S+ S ITG ++ V G + Sbjct: 232 AFLFSDMSRGITGENLHVDSGFHI 255 >5YCX-A nrPDB Length = 266 Score = 147 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 50/260 (19%), Positives = 92/260 (35%), Gaps = 16/260 (6%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L+ +V G I ++ L GA + + VR L Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGER-LERNVRELADT-----LEG 59 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD---EFLLHMSEDDWDKV 123 DV+ E ++ V A +D + S D + Sbjct: 60 QESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLA 119 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 ++ V + A + + G+I+ ++ + G+ +KA + + Sbjct: 120 QNISAFSLTAVAREAKKVMTE---GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYL 176 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A +LG+HGIR N++ G I T + V ++ +I E P+ E+V D FL Sbjct: 177 ANDLGQHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLF 236 Query: 242 SEDSGYITGTSVEVTGGLFM 261 S+ + +TG ++ V G + Sbjct: 237 SDLARGVTGENIHVDSGYHI 256 >4ALL-A nrPDB Length = 277 Score = 137 bits (345), Expect = 6e-33, Method: Composition-based stats. Identities = 51/263 (19%), Positives = 90/263 (34%), Gaps = 16/263 (6%) Query: 5 LQNRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 L + ++ G I V+ L GA + + +E +LL E Sbjct: 21 HMLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPE 80 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD---EFLLHMSEDD 119 +Q DV EQ+ V S A + S + Sbjct: 81 AHL------YQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREG 134 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + ++ +V A + + GSI+ + + G+ +KA + Sbjct: 135 FLLAQDISSYSLTIVAHEAKKLMPE---GGSIVATTYLGGEFAVQNYNVMGVAKASLEAN 191 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADVV 237 + A +LG IR N++ G I T + V ++ +I E P+ D +V Sbjct: 192 VKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTA 251 Query: 238 AFLASEDSGYITGTSVEVTGGLF 260 A+L S+ S +TG ++ V G Sbjct: 252 AYLLSDLSSGVTGENIHVDSGFH 274 >5KOI-A nrPDB Length = 293 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 43/264 (16%), Positives = 92/264 (34%), Gaps = 21/264 (7%) Query: 5 LQNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 ++ ++ L+ G + + ++ +LA +GA +A LG Sbjct: 22 MEGLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTY--------QGDALGKRVKPL 73 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLH-----MSE 117 G+ DV + + E+++ + +V G + L + Sbjct: 74 AEQVGSDFVLPCDVEDIATVDAVFEEIEKKWGGL-DFLVHAIGFSDKTELKGRYADVTTR 132 Query: 118 DDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVI 177 +++ + + ++ V Q A + + GSI+ ++ +KA + Sbjct: 133 ENFSRTMVISAYSFTEVAQRAEKLMKD---GGSILTLTYGGSTRTIPNYNVMGVAKAALE 189 Query: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVAD 235 + + A + G GIR N++ G + T + + P+ D +DV Sbjct: 190 AMVRYLAADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGK 249 Query: 236 VVAFLASEDSGYITGTSVEVTGGL 259 +L S+ S +TG V G Sbjct: 250 SAVYLLSDLSSGVTGEIHFVDSGY 273 >3E9N-A nrPDB Length = 245 Score = 133 bits (336), Expect = 6e-32, Method: Composition-based stats. Identities = 54/248 (21%), Positives = 101/248 (40%), Gaps = 24/248 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +A+VTGA G+G + L+ + V A + + G Sbjct: 3 LKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEG------------ 49 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 ++D+ + +++++ +V A + +D + S +W + +N+ Sbjct: 50 VEPIESDIVKEVLEEGGVDKLKNL--DHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNV 107 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 +++ AL + G +I I+S G + G T YAASK + GL +E Sbjct: 108 IVPAELSRQLLPALRA--ASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEA 165 Query: 189 RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 +GIR ++V PG TPM Q + I +P+++A+ + F+ D+G Sbjct: 166 NNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEI----YIEPKEIANAIRFVI--DAGET 219 Query: 249 TGTSVEVT 256 T V Sbjct: 220 T-QITNVD 226 >4ZJU-A nrPDB Length = 275 Score = 129 bits (325), Expect = 1e-30, Method: Composition-based stats. Identities = 49/262 (18%), Positives = 90/262 (34%), Gaps = 18/262 (6%) Query: 6 QNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63 Q L L+ G S I ++ L EGA +A + L + Sbjct: 11 QGLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNE--------KLKKRVDEFA 62 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE----DD 119 G+ F DV+ ++ + VV S ++ D Sbjct: 63 EQFGSKLVFPCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDG 122 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + ++ + +AA L + +G ++ ++ + +KA + Sbjct: 123 FKIAHDISAYSFVAMARAAKPLLQAR--QGCLLTLTYQGSERVMPNYNVMGMAKASLEAG 180 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVV 237 + A LG GIR N++ G I T + +K++D ++ P+ E+V + Sbjct: 181 VRYLASSLGVDGIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAA 240 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 FL S + ITG + V G Sbjct: 241 LFLCSPWASGITGEILYVDAGF 262 >4M89-A nrPDB Length = 261 Score = 128 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 52/262 (19%), Positives = 94/262 (35%), Gaps = 18/262 (6%) Query: 6 QNRLRSALALVTG--AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63 L+ L+TG + I ++ +GA +A V L K Sbjct: 1 MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTY--------VVDKLEERVRKMA 52 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDE----FLLHMSEDD 119 + F+ DV+ + + + +V S ++ FL +S + Sbjct: 53 AELDSELVFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREA 112 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 ++ ++ + +AA + G +I+ +S + +KA + Sbjct: 113 FNTAHEISAYSLPALAKAARPMM--RGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAG 170 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVV 237 + A LG+ GIRCN + G I T + K++ + P+ E+V + Sbjct: 171 IRFTAACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTA 230 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 AFL S+ S ITG V GG Sbjct: 231 AFLLSDLSSGITGEITYVDGGY 252 >5TF4-A nrPDB Length = 274 Score = 127 bits (320), Expect = 5e-30, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 88/259 (33%), Gaps = 20/259 (7%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L L+ G I ++ + GA +A A + Sbjct: 10 LYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEA--------MKKRVEPLAEEV 61 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGIT----QDEFLLHMSEDDWDK 122 DVS++ + + ++ + + +V G + + +SE ++ Sbjct: 62 KGFVCGHCDVSDSASIDAVFNTIEKKWGKL-DFLVHAIGFSDKEELSGRYVDISESNFMM 120 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 + +++ +T+ A + + GSI+ ++ + +KA + + Sbjct: 121 TMNISVYSLTALTKRAEKLM---SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKY 177 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFL 240 A +LG IR N++ G I T + ++ P+ E+V D +L Sbjct: 178 LAVDLGPKHIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYL 237 Query: 241 ASEDSGYITGTSVEVTGGL 259 S+ S +TG V G Sbjct: 238 LSDLSRSVTGEVHHVDSGY 256 >5CFZ-A nrPDB Length = 305 Score = 127 bits (319), Expect = 6e-30, Method: Composition-based stats. Identities = 50/262 (19%), Positives = 100/262 (38%), Gaps = 19/262 (7%) Query: 6 QNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63 L LVTG S I ++ + EGA +A + L G + Sbjct: 44 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--------DKLKGRVEEFA 95 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF----LLHMSEDD 119 G+ Q DV+E + + ++ + + V S D+ + ++ + Sbjct: 96 AQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREG 155 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + ++ + +A +++++ G +++ +S + + +KA + Sbjct: 156 FKIAHDISSYSFVAMAKAC-RSMLNPGS--ALLTLSYLGAERAIPNYNVMGLAKASLEAN 212 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVV 237 + A +G G+R N++ G I T + K++ + P+ EDV + Sbjct: 213 VRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 272 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 AFL S+ S I+G V V GG Sbjct: 273 AFLCSDLSAGISGEVVHVDGGF 294 >3GRK-A nrPDB Length = 293 Score = 127 bits (319), Expect = 6e-30, Method: Composition-based stats. Identities = 43/259 (16%), Positives = 89/259 (34%), Gaps = 18/259 (6%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L+ L+ G I ++ GA +A L Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTY--------QGDALKKRVEPLAEEL 80 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD---EFLLHMSEDDWDKV 123 G A DV++A + + E ++ + + +V + +D + SE ++ Sbjct: 81 GAFVAGHCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNT 140 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 + +++ V++ A + + GSI+ ++ + +KA + + Sbjct: 141 MLISVYSLTAVSRRAEKLMAD---GGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYL 197 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A +LG IR N++ G I T + ++ P+ ++V DV + Sbjct: 198 AVDLGPQNIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFL 257 Query: 242 SEDSGYITGTSVEVTGGLF 260 S+ S +TG G Sbjct: 258 SDLSRSVTGEVHHADSGYH 276 >4J3F-A nrPDB Length = 280 Score = 126 bits (317), Expect = 9e-30, Method: Composition-based stats. Identities = 49/264 (18%), Positives = 96/264 (36%), Gaps = 19/264 (7%) Query: 5 LQNRLRSALALVTG--AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 L L+TG + I ++ + EGA +A + + K Sbjct: 20 HMGFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQ---------FKDRVEKL 70 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD----EFLLHMSED 118 A DV + + L ++ + ++V S A +D F+ ++ + Sbjct: 71 CAEFNPAAVLPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTRE 130 Query: 119 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 + ++ + + + + S++ ++ I + +KA + Sbjct: 131 GFSIAHDISAYSFAALAKEGRSMMKNRN--ASMVALTYIGAEKAMPSYNTMGVAKASLEA 188 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVADV 236 + A LG GI+ N+V G I T + +K++D + P+ D +V + Sbjct: 189 TVRYTALALGEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNT 248 Query: 237 VAFLASEDSGYITGTSVEVTGGLF 260 VAFL S+ + ITG V V G Sbjct: 249 VAFLCSDMATGITGEVVHVDAGYH 272 >4NR0-A nrPDB Length = 273 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 49/262 (18%), Positives = 92/262 (35%), Gaps = 16/262 (6%) Query: 6 QNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63 L AL+ G S I ++ + EGA +A + G GS+ Sbjct: 1 MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPE 60 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMS----EDD 119 F DV++ + + + +V S D+ + + Sbjct: 61 ------LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREG 114 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + ++ + +A + + G GS++ +S + + +KA + Sbjct: 115 FRIAHDISAYSFIALAKAGREMMK--GRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAG 172 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVV 237 + A LG G R N+V G I T + +K++ P+ E+V + Sbjct: 173 VRYLAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAG 232 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 AFL S+ + I+G + V GG Sbjct: 233 AFLCSDLASGISGEILYVDGGF 254 >4JQC-A nrPDB Length = 282 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 50/263 (19%), Positives = 100/263 (38%), Gaps = 19/263 (7%) Query: 5 LQNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 L LVTG S I ++ + EGA +A + L G + Sbjct: 20 HMGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--------DKLKGRVEEF 71 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF----LLHMSED 118 G+ Q DV+E + + ++ + + V S D+ + ++ + Sbjct: 72 AAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTRE 131 Query: 119 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 + ++ + +A +++++ G +++ +S + + +KA + Sbjct: 132 GFKIAHDISSYSFVAMAKAC-RSMLNPGS--ALLTLSYLGAERAIPNYNVMGLAKASLEA 188 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADV 236 + A +G G+R N++ G I T + K++ + P+ EDV + Sbjct: 189 NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNS 248 Query: 237 VAFLASEDSGYITGTSVEVTGGL 259 AFL S+ S I+G V V GG Sbjct: 249 AAFLCSDLSAGISGEVVHVDGGF 271 >3K2E-A nrPDB Length = 296 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 88/259 (33%), Gaps = 18/259 (6%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 + ++ G + ++ + +GA VA L + L G K Sbjct: 28 MEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVK----- 82 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD---EFLLHMSEDDWDKV 123 DVS+A + + + + + VV + A ++ + S ++ Sbjct: 83 ---LTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTS 139 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 + ++ + A + + GSI+ +S + KA + + Sbjct: 140 MHISCYSFTYIASKAEPLMTN---GGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYL 196 Query: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVAFLA 241 A +LG+ IR N++ G + T + + ++ P+ +DV +L Sbjct: 197 AVDLGKQQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLL 256 Query: 242 SEDSGYITGTSVEVTGGLF 260 S+ TG +V V G Sbjct: 257 SDLGRGTTGETVHVDCGYH 275 >2DKN-A nrPDB Length = 255 Score = 124 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 65/276 (23%), Positives = 103/276 (37%), Gaps = 61/276 (22%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 + +TG+ SGIG A+ LA G TV D +A Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQAD------------------------I 38 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 +AD+S + V +V CAG+ ++ + V+AVN G Sbjct: 39 EADLSTPGGRETAVAAVLDRCGGVLDGLVCCAGVG-------VTAANSGLVVAVNYFGVS 91 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNV------------------------GQTN 168 + A+AL ++I + SI GQT+ Sbjct: 92 ALLDGLAEALSRGQQPAAVI-VGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTH 150 Query: 169 --YAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQ--KVPQKVVDKITEMI-P 223 YA SK V L + + G+R N V PG + TP+ Q K + + + P Sbjct: 151 LAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAP 210 Query: 224 MGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 +G +P +VA+ +AFL + +I G+ + V GG+ Sbjct: 211 LGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGM 246 >5I9N-A nrPDB Length = 276 Score = 123 bits (310), Expect = 6e-29, Method: Composition-based stats. Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 19/262 (7%) Query: 6 QNRLRSALALVTG--AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63 L L+TG + I ++ EGA +A + GS+ Sbjct: 1 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE-- 58 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDE----FLLHMSEDD 119 F DV++ L ++ + +V S ++ FL ++ ++ Sbjct: 59 ------LVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTREN 112 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + ++ + +AA L + S++ +S + + +KA + Sbjct: 113 FRIAHDISAYSFPALAKAALPMLSDD---ASLLTLSYLGAERAIPNYNTMGLAKAALEAS 169 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVV 237 + A LG G+R N++ G I T + K++D + P+ E V + Sbjct: 170 VRYLAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAG 229 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 AFL S+ + +T + V G Sbjct: 230 AFLLSDLASGVTAEVMHVDSGF 251 >4NK4-A nrPDB Length = 301 Score = 119 bits (300), Expect = 1e-27, Method: Composition-based stats. Identities = 46/262 (17%), Positives = 92/262 (35%), Gaps = 18/262 (6%) Query: 5 LQNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 + N L+ L+ G + I ++ L GA +A +G Sbjct: 35 MINILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSY--------QGESIGKRLKPL 86 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD---EFLLHMSEDD 119 + +V + + L E+++ + VV S A ++ + S D+ Sbjct: 87 ALTVDSDFMIPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDN 146 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 + + + V+ + + AAQ + G++I ++ A +K+ + Sbjct: 147 FIQTMLVSCFSFTEIVRRAAQLM---PHGGAMITLTYGGSMRVVPNYNAMAPAKSALESS 203 Query: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVV 237 T+ A + G IR N++ G + T + + E P+ ED+ + Sbjct: 204 TKYLACDYGGMNIRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSA 263 Query: 238 AFLASEDSGYITGTSVEVTGGL 259 +L S S +TG V G Sbjct: 264 LYLLSYLSNGVTGEIHYVDCGY 285 >3UCF-A nrPDB Length = 223 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 49/253 (19%), Positives = 90/253 (35%), Gaps = 42/253 (16%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 + +V G SGIG ++ +L E V Sbjct: 8 VYVVLGGTSGIGAELAKQLESEHTIVHVASRQTG-------------------------- 41 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 D+S+ ++ E + ++V+ ++ + G Sbjct: 42 -LDISDEKSVYHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAV 96 Query: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192 L + A+ L GSI S ++ + AA A + T+ A+EL I Sbjct: 97 LAAKHGARYLKQ---GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--I 151 Query: 193 RCNSVLPGFIATP----MTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 R N++ PG T M + + +P+G +G+ D+A +A+L + + Y+ Sbjct: 152 RVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIA--MAYLFAIQNSYM 209 Query: 249 TGTSVEVTGGLFM 261 TGT ++V GG + Sbjct: 210 TGTVIDVDGGALL 222 >1FJH-A nrPDB Length = 257 Score = 117 bits (294), Expect = 5e-27, Method: Composition-based stats. Identities = 62/278 (22%), Positives = 102/278 (36%), Gaps = 63/278 (22%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 + +++G +GIG A L G + D+ A Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE------------------------V 38 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 AD+S A + + V A S+ +V CAG+ +L V++VN G Sbjct: 39 IADLSTAEGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVLG-------NVVSVNYFGAT 91 Query: 133 LVTQAAAQALVSNGCRGSIINISSIV----GKVGNV------------------------ 164 + A AL +++ ISS+ N Sbjct: 92 ELMDAFLPALKKGHQPAAVV-ISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQG 150 Query: 165 GQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK--VPQKVVDKITEMI 222 G YA SK + + A G G+R N++ PG TP+ Q + + I + + Sbjct: 151 GNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFV 210 Query: 223 P-MGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 P MG +P ++A V+AFL S + Y+ G + + GG+ Sbjct: 211 PPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGI 248 >2HRB-A nrPDB Length = 274 Score = 114 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 54/262 (20%), Positives = 88/262 (33%), Gaps = 67/262 (25%) Query: 11 SALALVTGAGSGIGRAVSVRLAGE--GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 S +ALVTGA GIG A++ L + G V D A Q V+ L G Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSG-DVVLTARDVARGQAAVQQLQAEGLSPRFH--- 57 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGIT---QDEFLLHMSEDDWDKVIA 125 Q D+ + ++ R L + ++ + +V+V+ A + D + + + Sbjct: 58 ----QLDIDDLQSIRALRDFLRKEYGGL-NVLVNNAAVAFKSDDPMPFDIKAE---MTLK 109 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISS----------------------------- 156 N T + + G ++NISS Sbjct: 110 TNFFATRNMCNELLPIMK---PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLV 166 Query: 157 -------------IVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH----GIRCNSVLP 199 + + G + Y SK GV L++ AR L I N+ P Sbjct: 167 DLMKKFVEDTKNEVHEREGWPN-SPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCP 225 Query: 200 GFIATPMTQKVPQKVVDKITEM 221 G + T M K + V++ E Sbjct: 226 GPVKTDMDGKDSIRTVEEGAET 247 >3DWF-A nrPDB Length = 276 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 13/200 (6%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +VTGA GIGR ++ LA GA V + A Q+ V G+ + Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGA------AS 62 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 + + A + + +++ + H D+ K + VN Sbjct: 63 AHYIAGSMEDMTFAEEFVAEAGNLMGGL-DMLILNHVLYNRLTFFHGEIDNVRKSMEVNF 121 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG 188 +++ AA L+ +GSI +SS+ GK+ Y+ASK + G T E Sbjct: 122 HSFVVLSVAAMPMLMQ--SQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFL 179 Query: 189 RHGIRCN---SVLPGFIATP 205 + + + +L G I T Sbjct: 180 VNKVNVSITLCIL-GLIDTE 198 >3KZV-A nrPDB Length = 254 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 38/218 (17%), Positives = 74/218 (33%), Gaps = 14/218 (6%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 + LVTG GIG+++ L + R+ A + Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEA--------PLKKLKEKYGDRFF 53 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 D++E + L+ + S+V + + + + + + W K+ +N Sbjct: 54 YVVGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFS 113 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190 + A L G+++ +SS + Y +SKA + T A E Sbjct: 114 IVSLVGIALPELKKTN--GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ER 169 Query: 191 GIRCNSVLPGFIATPMTQKVPQKV--VDKITEMIPMGH 226 ++ +V PG + T M + + V E + M Sbjct: 170 QVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFR 207 >2PD3-A nrPDB Length = 275 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 46/262 (17%), Positives = 92/262 (35%), Gaps = 18/262 (6%) Query: 6 QNRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63 L+ L+ G I ++ +GAT+A L+ + L Sbjct: 1 MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNES--------LEKRVRPIA 52 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF---LLHMSEDDW 120 + ++ DVS+ + L V+ +V S A ++ LL S+ + Sbjct: 53 QELNSPYVYELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAF 112 Query: 121 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180 + + +++ +T L S++ +S + +KA + Sbjct: 113 NTAMEISVYSLIELTNTLKPLL---NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAV 169 Query: 181 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQ--KVVDKITEMIPMGHLGDPEDVADVVA 238 + A +LG+H IR N++ G I T + + ++ P+ E+V + Sbjct: 170 RYLAVDLGKHHIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGM 229 Query: 239 FLASEDSGYITGTSVEVTGGLF 260 +L S S ++G V G Sbjct: 230 YLLSSLSSGVSGEVHFVDAGYH 251 >5L51-A nrPDB Length = 324 Score = 106 bits (266), Expect = 7e-24, Method: Composition-based stats. Identities = 48/275 (17%), Positives = 85/275 (30%), Gaps = 83/275 (30%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 A+VTGA GIG + +LA +G TV D E L E Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGD--YV 71 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGI----------------------- 106 + Q DV++ + L++ ++ F ++V+ AG+ Sbjct: 72 VSQQLDVADPASVAALVDFIKTKFGSL-DILVNNAGLNGTYMEGDASVLNDYVEAEFKTF 130 Query: 107 ---------TQDEFLLHM--SEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINIS 155 + + + + + I N G+ VT+A L + I+N+S Sbjct: 131 QSGAAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSP-RIVNVS 189 Query: 156 SIVGKVGN-------------------------------------------VGQTNYAAS 172 S + + + Y S Sbjct: 190 STLSSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVS 249 Query: 173 KAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMT 207 KA + T+ A++ R N+V PG+ T ++ Sbjct: 250 KAALNAYTRIIAKKYPSF--RINAVCPGYTKTDLS 282 >5PGZ-A nrPDB Length = 276 Score = 106 bits (266), Expect = 8e-24, Method: Composition-based stats. Identities = 49/201 (24%), Positives = 76/201 (37%), Gaps = 15/201 (7%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L+ +VTGA GIGR ++ L+ GA V Q+ V G+ Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEF-LLHMSEDDWDKVIAVN 127 + + A + + ++++ ITQ L H +V+ VN Sbjct: 76 T------MEDMTFAEQFIVKAGKLMGGLDMLILNH--ITQTSLSLFHDDIHSVRRVMEVN 127 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 +++ AA L + GSI ISS+ GK+ Y+ASK + G T EL Sbjct: 128 FLSYVVMSTAALPMLKQSN--GSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 Query: 188 GRHGIRCN---SVLPGFIATP 205 + + VL G I T Sbjct: 186 YITKVNVSITLCVL-GLIDTE 205 >4Q9N-A nrPDB Length = 298 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 55/282 (19%), Positives = 100/282 (35%), Gaps = 35/282 (12%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATVAA-----CDLDRAAAQETVRLLGGPGSK 61 L +A + G G +G G ++ LA GAT+ + + E + Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 62 EGPPRGNHAAFQADVS--------------------EARAARCLLEQVQACFSRPPSVVV 101 G + D S ++EQV+ F +V Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 102 SCAGITQ-DEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGK 160 S A + + LL S + ++ + + + S I+++ + Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM---NAGASTISLTYLASM 182 Query: 161 VGNVGQTN-YAASKAGVIGLTQTAARELGRH-GIRCNSVLPGFIATPMTQKVP--QKVVD 216 G A+KA + T+ A E GR G+R N++ G +A+ + + +++VD Sbjct: 183 RAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGFIERMVD 242 Query: 217 KITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 + P+ + E V AFL S + ITG ++ V G Sbjct: 243 YYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHG 284 >1N5D-A nrPDB Length = 288 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 53/243 (21%), Positives = 84/243 (34%), Gaps = 61/243 (25%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGA-TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +ALVTGA GIG A+ L + A V D A Q V+ L G Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFH----- 59 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK--VIAVNL 128 Q D+ + ++ R L + ++ + V+V+ A I L + + + N Sbjct: 60 --QLDIIDLQSIRALCDFLRKEYGGL-DVLVNNAAIAFQ--LDNPTPFHIQAELTMKTNF 114 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVG------------------------KVGNV 164 GT V + G ++N+SS G VG + Sbjct: 115 MGTRNVCTELLPLIKPQ---GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLM 171 Query: 165 GQ-----------------TNYAASKAGVIGLTQTAAREL----GRHGIRCNSVLPGFIA 203 + + Y +K GV L++ AR+L I N+ PG++ Sbjct: 172 NKFVEDTKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVR 231 Query: 204 TPM 206 T M Sbjct: 232 TDM 234 >3O26-A nrPDB Length = 311 Score = 102 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 48/284 (16%), Positives = 83/284 (29%), Gaps = 82/284 (28%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 A+VTG GIG + +L+ G V D E V L + N Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHE------NVVF 66 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGIT------------------------ 107 Q DV++ A L ++V+ AG+ Sbjct: 67 HQLDVTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELV 126 Query: 108 ------QDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKV 161 + + L+ + + ++ + +N G VT+ L + I+N+SS G + Sbjct: 127 KIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSP-RIVNVSSSTGSL 185 Query: 162 GNVGQ-------------------------------------------TNYAASKAGVIG 178 V Y SKA + Sbjct: 186 KYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNA 245 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMI 222 T+ A ++ + N V PG + T M + ++ E + Sbjct: 246 YTRVLANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHV 287 >3BHI-A nrPDB Length = 276 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 59/291 (20%), Positives = 92/291 (31%), Gaps = 82/291 (28%) Query: 13 LALVTGAGSGIGRAVSVRLAG--EGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +ALVTG GIG A+ L G V D Q V+ L G Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSG-DVVLTARDVTRGQAAVQQLQAEGLSPRFH----- 59 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK--VIAVNL 128 Q D+ + ++ R L + ++ + V+V+ AGI + + + N Sbjct: 60 --QLDIDDLQSIRALRDFLRKEYGGL-DVLVNNAGIA--FKVADPTPFHIQAEVTMKTNF 114 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVG----------------------------- 159 GT V + G ++N+SSI+ Sbjct: 115 FGTRDVCTELLPLIKPQ---GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLM 171 Query: 160 -------------KVGNVGQTNYAASKAGVIGLTQTAARELGR----HGIRCNSVLPGFI 202 K G + Y +K GV L++ AR+L I N+ PG++ Sbjct: 172 NKFVEDTKKGVHQKEGWP-SSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWV 230 Query: 203 ATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLA--SEDSGYITGT 251 T M K PE+ A+ +LA D+ G Sbjct: 231 RTDMAGPKATK---------------SPEEGAETPVYLALLPPDAEGPHGQ 266 >1ENP-A nrPDB Length = 312 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 58/283 (20%), Positives = 100/283 (35%), Gaps = 35/283 (12%) Query: 9 LRSALALVTGAG--SGIGRAVSVRLAGEGATV-AACDLDRAAAQETVRLLGGPGSKEGPP 65 LR A + G +G G AV+ LA GA + + ET G P Sbjct: 16 LRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLP 75 Query: 66 RGNHAAFQ------------ADV------------SEARAARCLLEQVQACFSRPPSVVV 101 G+ + DV S + E V+ F +V Sbjct: 76 DGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILVH 135 Query: 102 SCA-GITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGK 160 S A G + LL S + I+ + + + G+ I+++ I + Sbjct: 136 SLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM---NPGGASISLTYIASE 192 Query: 161 VGNVGQ-TNYAASKAGVIGLTQTAARELGRH-GIRCNSVLPGFIATPMTQKVP--QKVVD 216 G +++KA + T+ A E GR IR N++ G + + + + +++ Sbjct: 193 RIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKAIGFIDTMIE 252 Query: 217 KITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 P+ ++V + AFL S + ITG ++ V GL Sbjct: 253 YSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGL 295 >1SNY-A nrPDB Length = 267 Score = 101 bits (251), Expect = 5e-22, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 77/210 (36%), Gaps = 26/210 (12%) Query: 15 LVTGAGSGIGRAVSVRLA---GEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 L+TG G+G + L + +R A+E L N Sbjct: 25 LITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNH--------SNIHI 76 Query: 72 FQADVSEARAARCLLEQVQA-CFSRPPSVVVSCAGITQ-DEFLLHMSEDDWDKVIAVNLK 129 + D+ A L+ ++ + +V+ + AGI + + + + N Sbjct: 77 LEIDLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTV 136 Query: 130 GTFLVTQAAAQALVSNG----------CRGSIINISSIVGKVGN---VGQTNYAASKAGV 176 ++ +A L R +IIN+SSI+G + G Y SK+ + Sbjct: 137 VPIMLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSAL 196 Query: 177 IGLTQTAARELGRHGIRCNSVLPGFIATPM 206 T++ + +L I C S+ PG++ T M Sbjct: 197 NAATKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >2O2S-A nrPDB Length = 315 Score = 101 bits (251), Expect = 5e-22, Method: Composition-based stats. Identities = 57/296 (19%), Positives = 101/296 (34%), Gaps = 41/296 (13%) Query: 3 SQLQNRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAAC-----------DLDRAAAQ 49 S LR A V G G G A++ LA GA VA L Sbjct: 1 SAFPIDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLD 60 Query: 50 ETVRLLGGPGSKEGPPRGNHAAF------QADVSEAR--------AARCLLEQVQACFSR 95 E +L G + AAF D+ + + + + +V+ Sbjct: 61 EDRKLPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGN 120 Query: 96 PPSVVVSCA-GITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINI 154 +V S A G + LL S + + + + Q + GS + + Sbjct: 121 IDILVHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM---NEGGSAVTL 177 Query: 155 SSIVGKVGNVGQTN-YAASKAGVIGLTQTAARELG-RHGIRCNSVLPGFIATPMTQKVPQ 212 S + + G +++KA + T+T A E G ++G+R N++ G + + + + Sbjct: 178 SYLAAERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGK 237 Query: 213 KVVDKITE--------MIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLF 260 + P+ +DV FL S + ++G ++ V GL Sbjct: 238 SGEKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLH 293 >1B15-A nrPDB Length = 254 Score = 99.1 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 20/204 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L + + A GIG S L LDR + L K P+ N Sbjct: 3 LTNKNVIFVAALGGIGLDTSRELVKRNLKNFVI-LDRVENPTALAEL-----KAINPKVN 56 Query: 69 HAAFQADVSEA-RAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 DV+ ++ LL+++ + ++++ AGI + + ++ IA+N Sbjct: 57 ITFHTYDVTVPVAESKKLLKKIFDQL-KTVDILINGAGI--------LDDHQIERTIAIN 107 Query: 128 LKGTFLVTQAAAQAL-VSNGCRGSII-NISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 G T A G G II NI S+ G Y+ASKA V+ T + A+ Sbjct: 108 FTGLVNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK 167 Query: 186 ELGR-HGIRCNSVLPGFIATPMTQ 208 L G+ S+ PG TP+ Sbjct: 168 -LAPITGVTAYSINPGITRTPLVH 190 >4HWK-A nrPDB Length = 288 Score = 92.6 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 52/240 (21%), Positives = 86/240 (35%), Gaps = 22/240 (9%) Query: 5 LQNRLRSALALVTGAGSGIGR---AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSK 61 ++ L A+ L+TGA G GR + L G+ + + A ++ LG S Sbjct: 28 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS- 86 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQAC---FSRPPSVVVSCAGITQDEFLLHMSED 118 AD+ + LL ++ ++++ AG D + Sbjct: 87 ----GLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLS 142 Query: 119 DWDKVIA---VNLKGTFLVTQAAAQALVSNGCRGS-IINISSIVGKVGNVGQTNYAASKA 174 D +V +NL +T + +A + ++NISS+ G Y A KA Sbjct: 143 DSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKA 202 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQ-----KVPQKVVDKITEMIPMGHLGD 229 L Q A E +R + PG + T M Q V + + E+ G L D Sbjct: 203 ARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 260 >4Z3K-A nrPDB Length = 275 Score = 92.2 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 52/240 (21%), Positives = 86/240 (35%), Gaps = 22/240 (9%) Query: 5 LQNRLRSALALVTGAGSGIGR---AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSK 61 ++ L A+ L+TGA G GR + L G+ + + A ++ LG S Sbjct: 15 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS- 73 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQAC---FSRPPSVVVSCAGITQDEFLLHMSED 118 AD+ + LL ++ ++++ AG D + Sbjct: 74 ----GLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLS 129 Query: 119 DWDKVIA---VNLKGTFLVTQAAAQALVSNGCRGS-IINISSIVGKVGNVGQTNYAASKA 174 D +V +NL +T + +A + ++NISS+ G Y A KA Sbjct: 130 DSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKA 189 Query: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQ-----KVPQKVVDKITEMIPMGHLGD 229 L Q A E +R + PG + T M Q V + + E+ G L D Sbjct: 190 ARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 247 >2PTG-A nrPDB Length = 319 Score = 91.8 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 57/303 (18%), Positives = 99/303 (32%), Gaps = 54/303 (17%) Query: 9 LRSALALVTGA--GSGIGRAVSVRLAGEGATVAAC------------------DLDRAAA 48 LR A V G +G G A+ L GA V + D A Sbjct: 7 LRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 49 QETVRLLGGPGSKEGPPRGNHAAFQAD------------VSEAR--------AARCLLEQ 88 QE + +++ + D VS + + E Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEA 126 Query: 89 VQACFSRPPSVVVSCA-GITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGC 147 V+A + +V S A G + LL S + ++ + + Q + Sbjct: 127 VRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE--- 183 Query: 148 RGSIINISSIVGKVGNVGQTN-YAASKAGVIGLTQTAARELGR-HGIRCNSVLPGFIATP 205 GS + +S I + G +++KA + +T A E GR +R N + G + + Sbjct: 184 GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSR 243 Query: 206 MTQKVPQK--------VVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTG 257 + + +D P+ + +DV FL S + +TG ++ V Sbjct: 244 AASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDN 303 Query: 258 GLF 260 GL Sbjct: 304 GLH 306 >1MG5-A nrPDB Length = 255 Score = 91.4 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 49/206 (23%), Positives = 74/206 (35%), Gaps = 20/206 (9%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L + + GIG S L LDR + L K P+ Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVI-LDRIENPAAIAEL-----KAINPKVT 57 Query: 69 HAAFQADVSEA-RAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + DV+ LL+ + A + V+++ AGI + + ++ IAVN Sbjct: 58 VTFYPYDVTVPIAETTKLLKTIFAQL-KTVDVLINGAGI--------LDDHQIERTIAVN 108 Query: 128 LKGTFLVTQAAAQAL-VSNGCRGSII-NISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 G T A G G II NI S+ G Y+ +KA V+ T + A+ Sbjct: 109 YTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK 168 Query: 186 ELGR-HGIRCNSVLPGFIATPMTQKV 210 L G+ +V PG T + K Sbjct: 169 -LAPITGVTAYTVNPGITRTTLVHKF 193 >3U9L-A nrPDB Length = 324 Score = 91.0 bits (225), Expect = 5e-19, Method: Composition-based stats. Identities = 52/239 (21%), Positives = 86/239 (35%), Gaps = 20/239 (8%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 + + L+TGA SG GR + LAG G V A D + + Sbjct: 3 MSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRN--ASNVEAIAGFARDNDVD 60 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128 + DV + ++Q+ R V++ AG + + + ++ +N+ Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRI-DVLIHNAGHMVFGPAEAFTPEQFAELYDINV 119 Query: 129 KGTFLVTQAAAQALVSNGCRGSI-INISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 T V +AA + I I+ SS G Y A+KA + + AREL Sbjct: 120 LSTQRVNRAALPHMRRQKHGLLIWISSSSSAGGTP-PYLAPYFAAKAAMDAIAVQYAREL 178 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 R GI + ++PG + H G P+D A + A ++G Sbjct: 179 SRWGIETSIIVPGAFTSGTNH---------------FAHSGVPDDHARQAEYEAGPNAG 222 >5LCX-A nrPDB Length = 316 Score = 87.9 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 53/300 (17%), Positives = 92/300 (30%), Gaps = 88/300 (29%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 ALVTGA GIG + +LA +G V + E + L Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKE---LNVSENRLVF 64 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMS------EDDWD---- 121 Q DV++ + + +++ F + ++V+ AG++ E + +S E D+ Sbjct: 65 HQLDVTDLASVAAVAVFIKSKFGKL-DILVNNAGVSGVEMVGDVSVFNEYIEADFKALQA 123 Query: 122 ---------------------------KVIAVNLKGTFLVTQAAAQALVSNGCRGSIINI 154 + N G +TQA L+ I+N+ Sbjct: 124 LEAGAKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIP-LLQLSPSPRIVNV 182 Query: 155 SSIV------------GKVG-------------------------------NVGQTNYAA 171 SS G +G Sbjct: 183 SSSFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERV 242 Query: 172 SKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPE 231 SKA + T+ AA++ R N++ PG+ T +T V + +P+ P+ Sbjct: 243 SKAALNAYTKIAAKKYPSF--RINAICPGYAKTDITFHAGPLSVAE-AAQVPVKLALLPD 299 >1OAA-A nrPDB Length = 259 Score = 87.6 bits (216), Expect = 5e-18, Method: Composition-based stats. Identities = 47/214 (21%), Positives = 79/214 (36%), Gaps = 17/214 (7%) Query: 13 LALVTGAGSGIGRAVSVRLAGE---GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + ++TGA G GRA++ +LA G+ + + ++ LG P Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQ-----QPDLKV 62 Query: 70 AAFQADVSEARAARCLLEQVQAC---FSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA- 125 AD+ + LL V+ ++++ A D ++ +D +V Sbjct: 63 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 122 Query: 126 --VNLKGTFLVTQAAAQALVSN-GCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT 182 +NL +T A + G +++NISS+ G Y A KA L Q Sbjct: 123 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 182 Query: 183 AARELGRHGIRCNSVLPGFIATPMTQKVPQKVVD 216 A E +R S PG + M Q + D Sbjct: 183 LAAE--EPSVRVLSYAPGPLDNDMQQLARETSKD 214 >4OYR-A nrPDB Length = 289 Score = 82.2 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 54/280 (19%), Positives = 87/280 (31%), Gaps = 35/280 (12%) Query: 3 SQLQNRLRSALALVTG--AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 S + L LV+G S I ++ +GA + DR L Sbjct: 19 SHMTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDR---------LRLIQR 69 Query: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFS---RPPSVVVSCAGITQDE----FLL 113 + DV L +V + VV S + Q Sbjct: 70 ITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFF 129 Query: 114 HMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASK 173 D K I ++ + +A + GSI+ + +K Sbjct: 130 DAPYADVSKGIHISAYSYASMAKALLPIM---NPGGSIVGM-DFDPSRAMPAYNWMTVAK 185 Query: 174 AGVIGLTQTAARELGRHGIRCNSVLPGFIAT-PMTQKVPQKVVDKITEMI---------- 222 + + + + ARE G++G+R N V G I T M+ V + ++ I Sbjct: 186 SALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQR 245 Query: 223 -PMGH-LGDPEDVADVVAFLASEDSGYITGTSVEVTGGLF 260 P+G + D VA V L S+ TG + GG Sbjct: 246 APIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAH 285 >3F4B-A nrPDB Length = 323 Score = 80.2 bits (197), Expect = 7e-16, Method: Composition-based stats. Identities = 37/206 (17%), Positives = 77/206 (37%), Gaps = 30/206 (14%) Query: 81 AARCLLEQVQACFSRPPSVVVSCA-GITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAA 139 + + + + + +V S A G + LL S D + I+ + + + Sbjct: 106 SIEEVANLIYNKYGKISMLVHSLANGREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFC 165 Query: 140 QALVSNGCRGSIINISSIVGKVGNVGQTN-YAASKAGVIGLTQTAARELGR-HGIRCNSV 197 + + GS+++++ + G +++KA + T+ A LGR + IR N++ Sbjct: 166 KFM---NSGGSVVSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTI 222 Query: 198 LPGFIATPMTQKVP------------------------QKVVDKITEMIPMGHLGDPEDV 233 G + + + +D + P+ DV Sbjct: 223 SAGPLKSRAATAINKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDV 282 Query: 234 ADVVAFLASEDSGYITGTSVEVTGGL 259 V +FL S++S +TG ++ V GL Sbjct: 283 GSVASFLLSKESSAVTGQTIYVDNGL 308 >5TQV-A nrPDB Length = 233 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 91/250 (36%), Gaps = 35/250 (14%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 L+ GA G+GR + +G V A D A+ L A Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL-------------GAHA 56 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGI--TQDEFLLHMSEDDWDKVIAVNLK 129 D+++ L ++ V V +G+ + E + ++ DD+D V+ N++ Sbjct: 57 HALDITQPEQIAALGWKLD---GERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVR 113 Query: 130 GTFLVTQAAAQALVSNGCRGSIIN--ISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 G + + ++++ + SI G G Y ASKA + + + A+ L Sbjct: 114 GPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWL-YRASKAALNDVLRIAS--L 170 Query: 188 GRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGY 247 C S+ PG++ T M Q +D T + M + +A+ A D Sbjct: 171 QTRHAACISLHPGWVRTDMGGA--QAALDPATSVTGMRRV-----IAE-----AGADVSQ 218 Query: 248 ITGTSVEVTG 257 G + G Sbjct: 219 SNGRFFQYDG 228 >5WQO-A nrPDB Length = 234 Score = 77.9 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 69/198 (34%), Gaps = 18/198 (9%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 L+ GA GIG ++ GA V A + L G + A Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQ-------AVT 61 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD--EFLLHMSEDDWDKVIAVNLKGT 131 D+++ A + E + R ++ AGI + + + + ++ N Sbjct: 62 GDLNQHDCAERIGEMLGE---RRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAP 118 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVG---NVGQTNYAASKAGVIGLTQTAARELG 188 + +A + + G + +SS + + + Y ASKA + L ++ E Sbjct: 119 LRLARALSGRV---SRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFE 175 Query: 189 RHGIRCNSVLPGFIATPM 206 + PG++ T M Sbjct: 176 ELPFSLLLLHPGWVRTEM 193 >2NTV-A nrPDB Length = 268 Score = 76.8 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 55/272 (20%), Positives = 89/272 (32%), Gaps = 35/272 (12%) Query: 9 LRSALALVTG--AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L LV+G S I ++ GA + DR + + Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIAD---------RLP 54 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFS---RPPSVVVSCAGITQDEF----LLHMSEDD 119 + DV L E+V A + VV S + Q +D Sbjct: 55 DKAPLIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYED 114 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 K I ++ + +A + GSI+ + +K+ + + Sbjct: 115 VSKGIHISTYSYASLAKALLLIM---NSGGSIVGM-DFDPTRAMPAYNWMTVAKSALESV 170 Query: 180 TQTAARELGRHGIRCNSVLPGFIAT-PMTQKVPQKVVDK-----------ITEMIPMGH- 226 + ARE G++G+R N V G I T M+ V ++ + P+G Sbjct: 171 NRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWN 230 Query: 227 LGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258 + DP VA V L SE TG+ + GG Sbjct: 231 MKDPTPVAKTVCALLSEWLPATTGSIIYADGG 262 >2O2Y-A nrPDB Length = 349 Score = 67.9 bits (165), Expect = 5e-12, Method: Composition-based stats. Identities = 35/227 (15%), Positives = 71/227 (31%), Gaps = 52/227 (22%) Query: 80 RAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAA 139 L+ Q + + + + +D LL+ S + ++ + + + Sbjct: 113 EDVANLIHQKYGKINMLVHSLANAKEVQKD--LLNTSRKGYLDALSKSSYSLISLCKYFV 170 Query: 140 QALVSNGCRGSIINISSIVGKVGNVGQTN-YAASKAGVIGLTQTAARELGR-HGIRCNSV 197 + SII+++ + G +++KA + T+ A LGR + IR N++ Sbjct: 171 NIMKPQS---SIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTI 227 Query: 198 LPGFIATP------------------------------MTQKVPQKVVDKITEM------ 221 G + + M ++ Sbjct: 228 SAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFID 287 Query: 222 ---------IPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGL 259 P+ D+ V +FL S +S ITG ++ V GL Sbjct: 288 YAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGL 334 >3SLK-A nrPDB Length = 795 Score = 66.8 bits (162), Expect = 9e-12, Method: Composition-based stats. Identities = 41/195 (21%), Positives = 72/195 (36%), Gaps = 32/195 (16%) Query: 13 LALVTGAGSGIGRAVSVRLA-GEGAT----VAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 LVTG +G V+ L G V+ + A E V L G++ Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQ-- 589 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 DV++ +L + P + VV AG+ D ++ + D+V+ Sbjct: 590 -----ACDVADRETLAKVLASIPDE--HPLTAVVHAAGVLDDGVSESLTVERLDQVLRPK 642 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL-------- 179 + G + + + ++ SS+ G +G+ GQ NYAA+ + + L Sbjct: 643 VDGARNLLELIDPDVA-------LVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRG 695 Query: 180 --TQTAARE-LGRHG 191 T++ A HG Sbjct: 696 LPTRSLAWGPWAEHG 710 >2PK3-A nrPDB Length = 321 Score = 54.0 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 47/274 (17%), Positives = 88/274 (32%), Gaps = 64/274 (23%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 AL+TG +G+ ++ L + V + A N Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEA-----------------KLPNVEMIS 57 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW---DKVIAVNLKG 130 D+ +++ + ++ + +P + A + +D W + N+ G Sbjct: 58 LDIMDSQRVKKVISDI-----KPDYIFHLAAKSSV--------KDSWLNKKGTFSTNVFG 104 Query: 131 TFLVTQAAAQALVSNGCRGSIINISS-------------IVGKVGNVGQTNYAASKAGVI 177 T V A + I+ I S + + + Y SKA V Sbjct: 105 TLHVLDAV----RDSNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVG 160 Query: 178 GLTQTAARELGRHGI---RCNSVLP----GFIATPMTQKVPQKVVDKITEMIPMGHLGDP 230 L + + G I N + P GF+ +++ ++K +I +G+L Sbjct: 161 MLARQYVKAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAV 220 Query: 231 EDVADV-----VAFLASEDSGYITGTSVEVTGGL 259 D DV +L S+ TG V G+ Sbjct: 221 RDFTDVRDIVQAYWLLSQYGK--TGDVYNVCSGI 252 >3ORF-A nrPDB Length = 251 Score = 51.0 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 32/201 (15%), Positives = 58/201 (28%), Gaps = 24/201 (11%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S LV G +G V + + D + + G Sbjct: 22 SKNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKDSG----------- 70 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 + ++E++ + + + V + G + +I +NL Sbjct: 71 --------EEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYS 122 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG-- 188 F A+ L G + + G Y A+KA + + A E G Sbjct: 123 AFASAHIGAKLL---NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGL 179 Query: 189 RHGIRCNSVLPGFIATPMTQK 209 G +LP + TP +K Sbjct: 180 PAGSTSLGILPVTLDTPTNRK 200 >4LIS-A nrPDB Length = 371 Score = 50.2 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 51/179 (28%), Gaps = 35/179 (19%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 LVTG IG ++ L G V D ++ E + + E Q Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRI------ELISGKKAEFAQ 59 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 DV++ A + E V+ A + D VN+ GT Sbjct: 60 LDVTDEAAFDKVFEAHPD-----IDSVIHFAALKAVGESGEKPLD----YYHVNVYGTI- 109 Query: 134 VTQAAAQALVSNGCRGSIINISS---------------IVGKVGNVGQTNYAASKAGVI 177 +++V + +I+ SS I Y +K + Sbjct: 110 ---CLLRSMVRHNVT-NIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >1OOE-A nrPDB Length = 236 Score = 48.3 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 63/204 (30%), Gaps = 25/204 (12%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 + +V G +G A+ G TV ++D +A + + G+K Sbjct: 4 GKV-IVYGGKGALGSAILEFFKKNGYTV--LNIDLSANDQADSNILVDGNKNWT------ 54 Query: 71 AFQADVSEARAARCLLEQVQACF-SRPPSVVVSCAGITQDEFLLHMS-EDDWDKVIAVNL 128 + +LEQ + V AG + D +I ++ Sbjct: 55 ---------EQEQSILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSV 105 Query: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR--E 186 + + + A L G + + Y +KA V LT + A Sbjct: 106 WSSAIAAKLATTHLK---PGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDS 162 Query: 187 LGRHGIRCNSVLPGFIATPMTQKV 210 +++P + TPM +K Sbjct: 163 GLPDNSAVLTIMPVTLDTPMNRKW 186 >6BWL-A nrPDB Length = 328 Score = 47.1 bits (111), Expect = 7e-06, Method: Composition-based stats. Identities = 56/266 (21%), Positives = 86/266 (32%), Gaps = 42/266 (15%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG IGR V RL + V D A T + + Q Sbjct: 4 LVTGGAGFIGRWVVKRLLQDKHEVWILD---NLANSTTANITEFAHDLNLKQ----CIQG 56 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 D+ + + L E F + A I + S DD + GTF + Sbjct: 57 DIKDKKLVAQLFEN--NSFDLCYHL---AASIN-----VQDSIDDARATFENDTIGTFNL 106 Query: 135 TQAAAQA------LVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT--AARE 186 + + + NI I + YA SK + + A + Sbjct: 107 LEQCLNYDVKMVFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYK 166 Query: 187 LGRHGIR-CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGD---------PEDVAD- 235 L IR N+ P F T V ++ + +P+ GD ED AD Sbjct: 167 LPVVVIRPFNTYGP-FQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCADF 225 Query: 236 -VVAFLASEDSGYI----TGTSVEVT 256 V A +++ +G+I TG + + Sbjct: 226 VVAAGYSAKANGHIINAGTGQDISIN 251 >1Z45-A nrPDB Length = 699 Score = 47.1 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 63/185 (34%), Gaps = 20/185 (10%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPG 59 M +QLQ+ S + LVTG IG V L G V A +L + RL Sbjct: 1 MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARL----- 55 Query: 60 SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD 119 E + + ++ D+ + + + ++ + V+ AG+ + Sbjct: 56 --EVLTKHHIPFYEVDLCDRKGLEKVFKEYK------IDSVIHFAGLKAVGESTQIPLRY 107 Query: 120 WD-----KVIAVNLKGTFLVTQ-AAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASK 173 + V+ + L + V++ + + G N+ I + Y +K Sbjct: 108 YHNNILGTVVLLELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTK 167 Query: 174 AGVIG 178 + Sbjct: 168 YAIEN 172 >1UDA-A nrPDB Length = 338 Score = 45.2 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 52/172 (30%), Gaps = 33/172 (19%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 LVTG IG V+L G V D + + + ++ G K + Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPT------FVE 56 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 D+ +L V+ AG+ + + +D N+ GT Sbjct: 57 GDIRNEALMTEILHD------HAIDTVIHFAGLKAVGESVQKPLEYYDN----NVNGTLR 106 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVG------------QTNYAASK 173 + A + + + + I SS N Q+ Y SK Sbjct: 107 LISA----MRAANVK-NFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSK 153 >3RFT-A nrPDB Length = 267 Score = 44.0 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 58/182 (31%), Gaps = 49/182 (26%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 LVTGA +GR + RLA E +RL S P N Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPM--------------AEILRL--ADLSPLDPAGPNEEC 47 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 Q D+++A A ++ +V GI+ ++ +++++ N+ G Sbjct: 48 VQCDLADANAVNAMVA--------GCDGIVHLGGISVEKP--------FEQILQGNIIGL 91 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQ------------TNYAASKAGVIGL 179 + + +AA + I+ SS Y SK L Sbjct: 92 YNLYEAA-----RAHGQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENL 146 Query: 180 TQ 181 + Sbjct: 147 AR 148 >1I3M-A nrPDB Length = 348 Score = 43.3 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 31/184 (16%), Positives = 56/184 (30%), Gaps = 29/184 (15%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 LVTG IG + L G D A + L + + + Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 D+ + A + L ++ V+ AG+ + D VNL GT Sbjct: 65 MDILDQGALQRLFKK------YSFMAVIHFAGLKAMGESVQKPLD----YYRVNLTGTIQ 114 Query: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQ-------------TNYAASKAGVIGLT 180 + + + ++G + +++ SS GN Y SK + + Sbjct: 115 L----LEIMKAHGVK-NLVF-SSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168 Query: 181 QTAA 184 + Sbjct: 169 RDLC 172 >3ENK-A nrPDB Length = 341 Score = 42.9 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 LVTG IG +V L G V D + +E + + K A Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTP------AFH 60 Query: 73 QADVSEARAARCLLEQ 88 + DVS+ RA + + Sbjct: 61 ETDVSDERALARIFDA 76 >1DIR-A nrPDB Length = 241 Score = 42.5 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 31/209 (14%), Positives = 59/209 (28%), Gaps = 24/209 (11%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + LV G +G VA+ D+ ++ S Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFT------- 58 Query: 70 AAFQADVSEARAARCLLEQVQACFS--RPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 A + +V + +++ G + D + + Sbjct: 59 ----------EQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQS 108 Query: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAA--R 185 + + + + A + L G + + G G Y +K V L Q+ A Sbjct: 109 IWTSTISSHLATKHLKE---GGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKN 165 Query: 186 ELGRHGIRCNSVLPGFIATPMTQKVPQKV 214 G +VLP + TPM +K + Sbjct: 166 SGMPSGAAAIAVLPVTLDTPMNRKSMPEA 194 >2Q1W-A nrPDB Length = 333 Score = 40.6 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 59/208 (28%), Gaps = 43/208 (20%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +TG IG ++ L G V D + N Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGID-----------NFATGRREHLKDHPNLTF 70 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 + +++ L+ +Q P VV A +D DDW N G Sbjct: 71 VEGSIADHALVNQLIGDLQ------PDAVVHTAASYKD-------PDDWYNDTLTNCVGG 117 Query: 132 FLVTQAAAQALVSNGCRGSIIN--ISSIVGKVG-----------NVGQTNYAASKAGVIG 178 V QAA G + + G N ++YA SK+ Sbjct: 118 SNVVQAA-----KKNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANED 172 Query: 179 LTQTAARELGRHGIRCNSVLPGFIATPM 206 + + + + N V P ++ P+ Sbjct: 173 YLEYSGLDFVTFRL-ANVVGPRNVSGPL 199 >4R1T-A nrPDB Length = 337 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 53/163 (32%), Gaps = 28/163 (17%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + + VTGAG I + L +G TV + + G + Sbjct: 2 SHGMRSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPK------NGHLREL 55 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 + +AD+ + ++ R + F V DD ++ Sbjct: 56 EGAKERLTLCKADLLDYQSLREAINGCDGVFHTASPV-----------------TDDPEQ 98 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVG 165 ++ + GT V AAA+A V ++ SSI + Sbjct: 99 MVEPAVIGTKNVINAAAEANVR-----RVVFTSSIGAVYMDPN 136 >1ZZE-A nrPDB Length = 342 Score = 39.4 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 46/157 (29%), Gaps = 25/157 (15%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 +L LVTGA + V +L G V + + P Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDA-----KYPGRFE 64 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 A D+ + V+ AG+ ++ S +D+V+ + Sbjct: 65 TAVVEDMLKQ--------------GAYDEVIKGAAGVAHIASVVSFSNK-YDEVVTPAIG 109 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISS-IVGKVGNVG 165 GT +AAA + + SS + + Sbjct: 110 GTLNALRAAA----ATPSVKRFVLTSSTVSALIPKPN 142 >3SXP-A nrPDB Length = 362 Score = 39.0 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 29/204 (14%), Positives = 59/204 (28%), Gaps = 32/204 (15%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEG--ATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L + L+TG +G ++ A V D R+ + G + Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 AD++ R L + + A ++ L + V+ Sbjct: 68 FKGEVIAADINNPLDLRRLEKL-------HFDYLFHQAAVSDTTMLNQ------ELVMKT 114 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSIINISS--IVGKVGNVGQT--------NYAASKAGV 176 N + + + ++ + +I SS + G Y SK + Sbjct: 115 NYQAFLNLLE------IARSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCM 168 Query: 177 IGLTQTAARELGRHGIR-CNSVLP 199 + + + + G+R N P Sbjct: 169 DEFVLSHSNDNVQVGLRYFNVYGP 192 >1KEU-A nrPDB Length = 361 Score = 39.0 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 65/209 (31%), Gaps = 45/209 (21%) Query: 15 LVTGAGSGIGRAVSVRLAG--EGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 L+TG IG AV + + V L A E++ + Sbjct: 4 LITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEH------- 56 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132 AD+ ++ + EQ Q P +V+ A D + + I N+ GT+ Sbjct: 57 -ADICDSAEITRIFEQYQ-----PDAVMHLAAESHVDRSI--TGPAAF---IETNIVGTY 105 Query: 133 LVTQAAAQAL------VSNGCRGSIINISSIVGKVGNVG-------------------QT 167 + + A + N R I+ + G + + + Sbjct: 106 ALLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSS 165 Query: 168 NYAASKAGVIGLTQTAARELGRHGIRCNS 196 Y+ASKA L + R G I N Sbjct: 166 PYSASKASSDHLVRAWRRTYGLPTIVTNC 194 >2GN9-A nrPDB Length = 344 Score = 38.6 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 28/171 (16%), Positives = 48/171 (28%), Gaps = 31/171 (18%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAG--EGATVAACDLDRAAAQETVRLLGGPGSKE 62 QN L + L+TG G+ ++ + D E P + Sbjct: 15 HQNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMR- 73 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 F DV + LE V + + A + + + Sbjct: 74 --------FFIGDVRDLERLNYALEGV--------DICIHAAALKHVPIAEYNPLE---- 113 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASK 173 I N+ G V A + +S +I +S+ Y A+K Sbjct: 114 CIKTNIMGASNVINACLKNAISQ-----VIALSTDKAANP---INLYGATK 156 >6GCS-E nrPDB Length = 375 Score = 38.6 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 20/136 (14%), Positives = 42/136 (30%), Gaps = 25/136 (18%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 A V GA +G ++ +LA G TV + K G Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYR---------EEMAKRHLKVTGDLGVV 102 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 + D+ + + R +VV+ G +++ V+++ Sbjct: 103 NFLEMDLRNLESIDEAV--------RHSDIVVNLIG-------REYETKNFN-YYDVHVE 146 Query: 130 GTFLVTQAAAQALVSN 145 G + +A + ++ Sbjct: 147 GARRIAEAVKKHNIAR 162 >2NNL-D nrPDB Length = 337 Score = 38.3 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 44/271 (16%), Positives = 93/271 (34%), Gaps = 54/271 (19%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 +S VTGA IG + +RL G TV A D ++ LL P ++ + Sbjct: 4 QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAET-----HL 58 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 ++AD+++ + ++ F + S+D ++VI ++ Sbjct: 59 TLWKADLADEGSFDEAIKGCTGVFH-------------VATPMDFESKDPENEVIKPTIE 105 Query: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQ-TNY----------AASK---AG 175 G + ++ A + ++ SS Q Y +K A Sbjct: 106 GMLGIMKSCA----AAKTVRRLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAW 161 Query: 176 VIGLTQTAARELG-----RHGIRCNSVLPGFIATPM-TQKVPQKVV---------DKITE 220 + +++T A + + I +++P + P +P ++ + Sbjct: 162 MYFVSKTLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYS 221 Query: 221 MIPMGHLGDPEDVADVVAFLASE---DSGYI 248 +I G +D+ + +L + YI Sbjct: 222 IIRQGQFVHLDDLCNAHIYLFENPKAEGRYI 252 >1VL0-A nrPDB Length = 292 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 54/180 (30%), Gaps = 55/180 (30%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 L+TGA +GR + +L G+ V D+ Sbjct: 16 LITGANGQLGREIQKQLKGKNVEVIPTDVQD----------------------------L 47 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 D++ A + + P+VV++CA T + E+ +D +N G + Sbjct: 48 DITNVLAVNKFFNE------KKPNVVINCAAHT----AVDKCEEQYDLAYKINAIGPKNL 97 Query: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVG-----------QTNYAASKAGVIGLTQTA 183 AA I+ IS+ G Q+ Y +K + Sbjct: 98 AAAAY------SVGAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >1BXK-A nrPDB Length = 355 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 34/191 (17%), Positives = 58/191 (30%), Gaps = 37/191 (19%) Query: 12 ALALVTGAGSGIGRAVSVRLAGE--GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 L+TG IG A+ + E A V L A ++ + Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQ--------SERF 53 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129 A + D+ + + + +P V+ A E + S D I N+ Sbjct: 54 AFEKVDICDRAELARVFTE-----HQPDCVMHLAA-----ESHVDRSIDGPAAFIETNIV 103 Query: 130 GTFLVTQAAAQAL------VSNGCRGSIINISSIVGK-----------VGNVGQTNYAAS 172 GT+ + +AA + R I+ + G + Y+AS Sbjct: 104 GTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSAS 163 Query: 173 KAGVIGLTQTA 183 KA L + Sbjct: 164 KASSDHLVRAW 174 >6DEB-A nrPDB Length = 285 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAA 48 L A++ GA + +GR ++ L GATV+ C + Sbjct: 158 LEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDL 197 >4PVC-A nrPDB Length = 342 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 26/148 (17%), Positives = 46/148 (31%), Gaps = 22/148 (14%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 V+GA I + + L E V + A+ G Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSME-------VV 55 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI-AVN-LKGT 131 D+S+ + V + +V+ A F +++ + D +I AVN +KG Sbjct: 56 PDISKLD----AFDHVFQKHGKDIKIVLHTA----SPFCFDITDSERDLLIPAVNGVKGI 107 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIVG 159 + A V ++ SS Sbjct: 108 LHSIKKYAADSVE-----RVVLTSSYAA 130 >1GY8-A nrPDB Length = 397 Score = 37.1 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 44/164 (26%), Gaps = 26/164 (15%) Query: 14 ALVTGAGSGIGRAVSVRLAGE-GATVAACDL---------DRAAAQETVRLLGGPGSKEG 63 LV G IG L + +V D + R L + Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 64 PPRGNHAAFQ-ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 P +AA + DV + +VV CA + E S D K Sbjct: 65 PWADRYAALEVGDVRNEDFLNGVF----TRHGPIDAVVHMCAFLAVGE-----SVRDPLK 115 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQ 166 N+ G + QA II SS GN Sbjct: 116 YYDNNVVGILRLLQAMLLH-----KCDKIIF-SSSAAIFGNPTM 153 >4G5H-A nrPDB Length = 363 Score = 37.1 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 22/138 (15%), Positives = 38/138 (27%), Gaps = 22/138 (15%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 + L+TG G AV R + D + + K Sbjct: 23 FDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLK------ 76 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 + DV ++++ + V V A + Q + + N Sbjct: 77 ---FYIGDVRDSQSVETAMRDV--------DYVFHAAALKQVPSCEFFPVEA----VKTN 121 Query: 128 LKGTFLVTQAAAQALVSN 145 + GT V Q+A V Sbjct: 122 IIGTENVLQSAIHQNVKK 139 >6ACF-A nrPDB Length = 367 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 24/74 (32%), Gaps = 11/74 (14%) Query: 6 QNRLRSALALVTGAGSGIG---RAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 + L + V G+G + L EGA + D+++ A V G Sbjct: 168 SDSLEGKVVAV----QGVGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAV-- 221 Query: 63 GPPRGNHAAFQADV 76 + + D+ Sbjct: 222 --DPNDIYGVECDI 233 >2PZM-A nrPDB Length = 330 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 58/176 (32%), Gaps = 40/176 (22%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 L+TG +G + +G + D +E + PP + + Sbjct: 24 LITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVL-----------PPVAGLSVIEG 72 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 V++A + + VV A +D DDW + A N++G+ V Sbjct: 73 SVTDAGLLERAFDSFKPTH------VVHSAAAYKD-------PDDWAEDAATNVQGSINV 119 Query: 135 TQAAAQALVSN----------GCRGSI-INISSIVGKVGNVGQTNYAASKAGVIGL 179 +AA++A V G ++ I I S T+Y SK Sbjct: 120 AKAASKAGVKRLLNFQTALCYGRPATVPIPIDS-----PTAPFTSYGISKTAGEAF 170 >5N2I-A nrPDB Length = 232 Score = 36.3 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 27/88 (30%), Gaps = 5/88 (5%) Query: 16 VTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQAD 75 V G GR ++ R A G V AQ LG G AA D Sbjct: 24 VLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGE-GLPVRGMDNAGAAEAGD 82 Query: 76 VSE----ARAARCLLEQVQACFSRPPSV 99 V R LLE ++ + V Sbjct: 83 VVIVAVPWDGHRALLESLKDVLAGKIVV 110 >5K1S-A nrPDB Length = 362 Score = 35.9 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 26/97 (26%), Gaps = 6/97 (6%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP------GSKEGP 64 L+TGA G+G + +GA V A A Q Sbjct: 184 GETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFASD 243 Query: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVV 101 R DV+ +Q + VVV Sbjct: 244 VRKRTQGAGVDVAVEIVGSATFDQTLKSMAPGGRVVV 280 >4KUG-A nrPDB Length = 290 Score = 35.9 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 30/93 (32%), Gaps = 6/93 (6%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 V GAG+ +G + A +G V D+ + + SK A Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCA 104 + ++ + ++ C +VV A Sbjct: 61 DKEEILSRISGTTDMKLAADC-----DLVVEAA 88 >4A10-A nrPDB Length = 447 Score = 35.9 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 32/92 (34%), Gaps = 2/92 (2%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + + L+ GA G+G + +++ G + + A + VR LG G Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 70 AAFQADVSE-ARAARCLLEQVQACFSRPPSVV 100 D R L + V R P +V Sbjct: 279 DDIADDPRRVVETGRKLAKLVVEKAGREPDIV 310 >2C20-A nrPDB Length = 330 Score = 35.6 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 33/113 (29%), Gaps = 11/113 (9%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 L+ G IG +L EG +V D + ++ + G+K AF Sbjct: 5 LICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITE----GAKFYNGDLRDKAFLR 60 Query: 75 DVSEARAARCLLEQVQACF-----SRPPSVVVSC--AGITQDEFLLHMSEDDW 120 DV ++ +P + + E + D + Sbjct: 61 DVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKF 113 >1LU9-A nrPDB Length = 287 Score = 35.2 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 26/79 (32%), Gaps = 4/79 (5%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 ++ A+V +G + LAGEGA V C AQ + K Sbjct: 115 GSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVN----KRFKVN 170 Query: 67 GNHAAFQADVSEARAARCL 85 A D S A A + Sbjct: 171 VTAAETADDASRAEAVKGA 189 >1OC2-A nrPDB Length = 348 Score = 34.8 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 39/130 (30%), Gaps = 18/130 (13%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +VTG IG + V LD+ + G + E Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDK------LTYAGNKANLEAILGDRVEL 58 Query: 72 FQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGT 131 D+++A L + A +V A D L S I N GT Sbjct: 59 VVGDIADAELVDKLAAKADA-------IVHYAAESHNDNSLNDPSPF-----IHTNFIGT 106 Query: 132 FLVTQAAAQA 141 + + +AA + Sbjct: 107 YTLLEAARKY 116 >4QUK-A nrPDB Length = 319 Score = 34.4 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 53/262 (20%), Positives = 87/262 (33%), Gaps = 52/262 (19%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 + VTGA I + L G TV A D ++ L+ G+KE F Sbjct: 2 VVCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKVDHLVKLDGAKERLQL-----F 56 Query: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDE-FLLHMSEDDWDKVIAVNLKGT 131 +A++ E SVV C G+ H +D ++I LKGT Sbjct: 57 KANLLEE--------------GAFDSVVQGCHGVFHTASPFYHDVKDPQAELIDPALKGT 102 Query: 132 FLVTQAAAQALVSNGCRGSIINISSIV--GKVGNVGQTNYAA-----------SKAGV-I 177 V + A + ++ SSI G + +K+ + Sbjct: 103 LNVLNSCA----KSPSLKRVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADFCAKSNLWY 158 Query: 178 GLTQTAARELG-----RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMI--------PM 224 ++ T A E + I ++ P + P+ Q V I +I Sbjct: 159 VVSATLAEEAAWKFVKENNIDMVTINPAMVIGPLLQPVLNTSAAAILNLINGAQTFPNAS 218 Query: 225 GHLGDPEDVADVVAFLASEDSG 246 + +DVA+ LA E++ Sbjct: 219 FGWVNVKDVANAHI-LAYENAS 239 >2HUN-A nrPDB Length = 336 Score = 34.4 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 66/180 (36%), Gaps = 30/180 (16%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG IG + + ++D+ L K+ + + Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANL-----KDLEDDPRYTFVKG 61 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 DV++ + L+ +V VV A + + + S + + + N+ GT+ + Sbjct: 62 DVADYELVKELVRKV--------DGVVHLAAESHVDRSIS-SPEIF---LHSNVIGTYTL 109 Query: 135 TQAAAQ--------ALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAG----VIGLTQT 182 ++ + + ++ G I+ S + + Y+A+KA V+G T+T Sbjct: 110 LESIRRENPEVRFVHVSTDEVYGDILK-GSFTENDRLMPSSPYSATKAASDMLVLGWTRT 168 >4K28-A nrPDB Length = 269 Score = 34.4 bits (78), Expect = 0.055, Method: Composition-based stats. Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEG-ATVAACDLDRAAAQETVRLLG 56 ALV G G G+G A++ LA G A++ CD A LLG Sbjct: 125 GKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLG 170 >6G2J-P nrPDB Length = 377 Score = 34.4 bits (78), Expect = 0.056, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 40/123 (32%), Gaps = 22/123 (17%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 ++ + +A V GA +GR V L G+ V +RL+G G Sbjct: 48 RSSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQLTFLE 107 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 D + + R ++ +VV++ D++ V Sbjct: 108 W--------DARDKDSIRKAVQH--------SNVVIN-----LIGREWETRNFDFEDVF- 145 Query: 126 VNL 128 VN+ Sbjct: 146 VNI 148 >6ACQ-A nrPDB Length = 302 Score = 34.0 bits (77), Expect = 0.064, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 28/91 (30%), Gaps = 11/91 (12%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 V GAG+ +G ++ A +G V D+ + + SK A Sbjct: 22 KKVCVIGAGT-MGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEA 80 Query: 72 FQ----------ADVSEARAARCLLEQVQAC 92 + D++ A ++E Sbjct: 81 TKVEILTRISGTVDLNMAADCDLVIEAAVER 111 >5F5N-A nrPDB Length = 289 Score = 34.0 bits (77), Expect = 0.072, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 25/83 (30%), Gaps = 11/83 (13%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 + LVTGA G A L G V A D G + + Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRD-----------PGTDAARALAAAGVS 49 Query: 71 AFQADVSEARAARCLLEQVQACF 93 D+++ + R + V F Sbjct: 50 LVTGDLNDQASLRAAMADVHGVF 72 >3OND-A nrPDB Length = 488 Score = 34.0 bits (77), Expect = 0.074, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD 44 + +A+V G G +G+ + L GA V ++D Sbjct: 263 IAGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEID 297 >5AOV-A nrPDB Length = 336 Score = 33.6 bits (76), Expect = 0.083, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 40/114 (35%), Gaps = 5/114 (4%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L + G G IG+A++ R +G + R + + LG Sbjct: 148 LYGKTIGIVGFGR-IGQAIARR--AKGFNMRILYYSRTRKSQAEKELGAEYRPLEEVLKE 204 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCA--GITQDEFLLHMSEDDW 120 V + ++ + + +P +++V+ A + + L+ ++ W Sbjct: 205 SDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGW 258 >3PEF-A nrPDB Length = 287 Score = 33.2 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 24/66 (36%), Gaps = 1/66 (1%) Query: 22 GI-GRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEAR 80 GI G A++ L G +V + A+E L + + A +++ Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAMLADPA 69 Query: 81 AARCLL 86 AA + Sbjct: 70 AAEEVC 75 >3CT4-A nrPDB Length = 332 Score = 33.2 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 30/99 (30%), Gaps = 8/99 (8%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEG---ATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 +ALV+G GSG A + GEG A V + + G Sbjct: 46 GKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLLI 104 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRP---PSVVVSC 103 + DV AR + E + + + V Sbjct: 105 -IKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVEN 142 >5B6K-A nrPDB Length = 366 Score = 33.2 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 21/161 (13%), Positives = 44/161 (27%), Gaps = 28/161 (17%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + V+GA I + V +L + V ++ G Sbjct: 19 SHMT------TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFN 72 Query: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122 D+S+ A + E+ + V + H + D +K Sbjct: 73 YE-------IVKDISDPTAFDHVFEK------HGKDIKV----VLHTASPFHFNTTDIEK 115 Query: 123 VIAVNLKGTFLVTQAAAQALVSNGCRG--SIINISSIVGKV 161 + L T+ +++ + ++ SS Sbjct: 116 DL---LIPAVNGTKGILESIKKYAAQTVERVVVTSSFAANT 153 >2P4H-X nrPDB Length = 322 Score = 33.2 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 27/95 (28%), Gaps = 7/95 (7%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + + VTG +G + L G +V + V L Sbjct: 1 KGRVC-VTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLP----GASEKL 55 Query: 70 AAFQADVSEARAARCLLEQVQACFSR--PPSVVVS 102 F AD+S + +E F P VS Sbjct: 56 HFFNADLSNPDSFAAAIEGCVGIFHTASPIDFAVS 90 >3VPX-A nrPDB Length = 364 Score = 33.2 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 21/53 (39%), Gaps = 1/53 (1%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG 59 + L V G G+ + A+ L EGA + D++ A Q V G Sbjct: 169 DSLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATA 220 >5GUP-L nrPDB Length = 377 Score = 32.9 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 54/169 (31%), Gaps = 31/169 (18%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 ++ + +A V GA +GR V L G+ V +R +G G Sbjct: 48 RSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFME 107 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + + R ++E +VV++ G D++ V Sbjct: 108 WNGK--------DKDSIRKVVEH--------SNVVINLVGREW-----ETKNFDFEDV-- 144 Query: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKA 174 F+ A + +I+IS + + + + Y SKA Sbjct: 145 ------FVKIPHAIAQVSKEAGVEKLIHISHLNADIKSP--SRYLRSKA 185 >2Z95-A nrPDB Length = 345 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 38/116 (32%), Gaps = 20/116 (17%) Query: 9 LRSALALVTGAGSGI-GRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 + AL+TG G G ++ L +G V D KE Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADRRSG-------EFASWRLKELGIEN 52 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCA-----GITQDEFLLHMSED 118 + D+ E +E+VQ P V + A G++ ++ +L D Sbjct: 53 DVKIIHMDLLEFSNIIRTIEKVQ------PDEVYNLAAQSFVGVSFEQPILTAEVD 102 >3N58-A nrPDB Length = 464 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETV 52 + +A+V G G +G+ + LAG GA V ++D A + Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAA 287 >3HZZ-A nrPDB Length = 467 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 30/92 (32%), Gaps = 1/92 (1%) Query: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 + L+ GA G+G + + + A G C + E R +G + G Sbjct: 246 QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGYK 304 Query: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVV 101 + + + ++++ +V Sbjct: 305 FWKDEHTQDPKEWKRFGKRIRELTGGEDIDIV 336 >4EUF-A nrPDB Length = 418 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 30/101 (29%), Gaps = 7/101 (6%) Query: 12 ALALVTGAGSGIGRA--VSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 L+ GA SG G A +SV G A + A + G + Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 70 AAFQA-----DVSEARAARCLLEQVQACFSRPPSVVVSCAG 105 A D +++ ++ F + V S A Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFVYSLAA 161 >4R1U-A nrPDB Length = 349 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 45/157 (28%), Gaps = 28/157 (17%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 VTGAG I + L G TV + + G + R Sbjct: 27 DQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPK------NGHLKELEGARERLT 80 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 + D+ + ++ + VV C G+ + + D+ L+ Sbjct: 81 LHKVDLLDLQSIQS--------------VVHGCHGVFHTASPVTDNPDEM-------LEP 119 Query: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQT 167 T+ A R ++ SSI + + Sbjct: 120 AVNGTKNVIIASAEAKVR-RVVFTSSIGTVYMDPNTS 155 >3NJ4-A nrPDB Length = 435 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRL 54 + +A+V G G +G+ + L G GA V ++D A + Sbjct: 214 IAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAME 258 >1O89-A nrPDB Length = 345 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 21/56 (37%), Gaps = 4/56 (7%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +VTGA G+G L G V A + + T L G+ PR A Sbjct: 172 VVTGASGGVGSTAVALLHKLGYQVVAV----SGRESTHEYLKSLGASRVLPRDEFA 223 >4J2O-A nrPDB Length = 363 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 39/140 (27%), Gaps = 26/140 (18%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 + + L+TG G AV R + D + + K Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLK------ 74 Query: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWD--KVIA 125 + DV + + +R I L + ++ + + Sbjct: 75 ---FYIGDVRDYNSILNA--------TRGVDY------IYHAAALKQVPSCEFHPMEAVK 117 Query: 126 VNLKGTFLVTQAAAQALVSN 145 N+ GT V +AA Q V Sbjct: 118 TNVLGTENVLEAAIQNHVKR 137 >3LK7-A nrPDB Length = 451 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 19/67 (28%), Gaps = 1/67 (1%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 + LV G G A + LA GA V D T + L G K Sbjct: 7 FENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVCGSHP 65 Query: 69 HAAFQAD 75 D Sbjct: 66 LELLDED 72 >3SC6-A nrPDB Length = 287 Score = 32.1 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 49/158 (31%), Gaps = 31/158 (19%) Query: 37 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRP 96 V + ++ L P D++ + ++++++ Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKLL----DITNISQVQQVVQEIRPH---- 58 Query: 97 PSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISS 156 +++ CA T+ + +E + D +N G V A A LV ++ IS+ Sbjct: 59 --IIIHCAAYTK----VDQAEKERDLAYVINAIGARNV--AVASQLV----GAKLVYIST 106 Query: 157 IVGKVG----------NVGQTN-YAASKAGVIGLTQTA 183 G N N Y ASK + Sbjct: 107 DYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >4B3J-A nrPDB Length = 736 Score = 32.1 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 27/103 (26%), Gaps = 17/103 (16%) Query: 19 AGSGIGRAVSVRLAGEGATVAACDLDRAAA----------QETVRLLGGPGSKEGPPRGN 68 +G ++ A G V D+ AA + G + Sbjct: 348 GAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSDALLA 407 Query: 69 HAAFQADVSEARAARCLLEQVQA-------CFSRPPSVVVSCA 104 AD ++ + ++E V F +V A Sbjct: 408 RITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNA 450 >3X2F-A nrPDB Length = 411 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 54/161 (33%), Gaps = 27/161 (16%) Query: 9 LRSALALVTGAGSG-IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 + +V AG G GR +++R AG GA V ++D A E + + + Sbjct: 195 VAGKNVVV--AGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAVKI 252 Query: 68 NHAAFQA----DVSEARAARCLLEQVQACFSRPPSVVVSCAGIT----QDEFLLHMSEDD 119 A DV L + V++ AG L ++ + Sbjct: 253 ADFVITASGNTDVLSKEDILSLKDGA----------VLANAGHFNVEIPVRVLEEIAVEK 302 Query: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGK 160 ++ N+ G L L G ++N+++ G Sbjct: 303 FEA--RPNVTGYTLENGKTVFLLAE----GRLVNLAAGDGH 337 Score = 27.5 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 26/193 (13%), Positives = 58/193 (30%), Gaps = 32/193 (16%) Query: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDR-AAAQETVRLLGGPGSKEG 63 + L + A +++ L+ GA V + + + L G Sbjct: 39 MSIHLEAKTAY-----------LAITLSKLGAKVVITGSNPLSTQDDVAEALRSKGITVY 87 Query: 64 PPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKV 123 R + + +L++ RP + I L +S + ++V Sbjct: 88 ARRTHDESIY-----RENLMKVLDE------RPDFI------IDDGGDLTVISHTEREEV 130 Query: 124 IAVNLKGTFLVTQAAAQALVSNGCRG--SIINISSIVGKVGNVGQTNYAASKAGVIGLTQ 181 + NLKG T + L + G + I+ K+ + Y ++ + + Sbjct: 131 LE-NLKGVSEETTTGVRRLKALEETGKLRVPVIAVNDSKMKYLFDNRYGTGQSTWDAIMR 189 Query: 182 TAARELGRHGIRC 194 + + Sbjct: 190 NTNLLVAGKNVVV 202 >1R66-A nrPDB Length = 337 Score = 32.1 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 36/182 (19%), Positives = 54/182 (29%), Gaps = 49/182 (26%) Query: 15 LVTGAGSGIGRAVSVRLAGEGA--------TVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 LVTG IG +L GA + L A + + + Sbjct: 4 LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNRANLAPVDA--------D 54 Query: 67 GNHAAFQADVSEARAARCLLEQVQA--CFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 D+ +A L V A F+ V S AG + Sbjct: 55 PRLRFVHGDIRDAGLLARELRGVDAIVHFAAESHVDRSIAGASVFT-------------- 100 Query: 125 AVNLKGTFLVTQAAAQALVSNGCRGSIINIS-----------SIVGKVGNVGQTNYAASK 173 N++GT + Q A + G ++++S S + YAASK Sbjct: 101 ETNVQGTQTLLQCAV-----DAGVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASK 155 Query: 174 AG 175 AG Sbjct: 156 AG 157 >6GBN-A nrPDB Length = 438 Score = 32.1 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETV 52 + +A+V G G +G+ + L G GA V ++D A + Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEIDPICALQAA 259 >5JXW-A nrPDB Length = 498 Score = 31.7 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 26/164 (15%), Positives = 47/164 (28%), Gaps = 27/164 (16%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L +V G G +G+ + L+G GA V ++D A + E Sbjct: 269 LAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEA 327 Query: 69 HAAFQA----DVSEARAARCLLEQV-QACFSRPPSV-----VVSCAGITQDEFLLHMSED 118 A DV R + E A + + GI ++ + ++ Sbjct: 328 DIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYGLENYPGI----KVIEVKQN 383 Query: 119 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVG 162 K L+ + G ++N+ G Sbjct: 384 VHKFTFPDTQKSVILLCK------------GRLVNLGCATGHPP 415 >6BII-A nrPDB Length = 333 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 17/121 (14%), Positives = 43/121 (35%), Gaps = 5/121 (4%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 + G G IG+A++ R G G + R E +E + Sbjct: 150 GKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARSRKPEAEKELGAEFKPLEELLRESDFV 208 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCA--GITQDEFLLHMSEDDWDKVIAVNL 128 +++ ++ + + +P +V+V+ A + + L+ ++ W +++ Sbjct: 209 VLAVPLTKET--YHMINEERLRLMKPTAVLVNVARGKVVDTKALIRALKEGWIAAAGLDV 266 Query: 129 K 129 Sbjct: 267 F 267 >3PVZ-A nrPDB Length = 399 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 37/124 (29%), Gaps = 12/124 (9%) Query: 15 LVTGAGSGIGRAVSVR-LAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 LV G IG+AV+ + D+ E VR + S G G+ F Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIR---SSFGYINGDFQTFA 95 Query: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 D+ + + V+ A + ++I VN+ T Sbjct: 96 LDIGSIE-----YDAFIKADGQYDYVLNLSA--LKHVRSEKDPFTLM-RMIDVNVFNTDK 147 Query: 134 VTQA 137 Q Sbjct: 148 TIQQ 151 >1DB3-A nrPDB Length = 372 Score = 31.7 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 44/127 (34%), Gaps = 12/127 (9%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +AL+TG G ++ L +G V + R A+ + Sbjct: 1 SKVALITGVTGQDGSYLAEFLLEKGYEV--HGIKRRASSFNTERVDHIYQDPHTCNPKFH 58 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 D+S+ +L +VQ P V + ++ +S + + V+ G Sbjct: 59 LHYGDLSDTSNLTRILREVQ------PDEVYNLGAMSHVA----VSFESPEYTADVDAMG 108 Query: 131 TFLVTQA 137 T + +A Sbjct: 109 TLRLLEA 115 >2EXX-A nrPDB Length = 306 Score = 31.7 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 27/86 (31%), Gaps = 12/86 (13%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEG-ATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 + L +V G G +V+ L +G V + ++ + L G++ Sbjct: 9 VDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPR--KKAAKELRLQGAE------ 60 Query: 68 NHAAFQADVSEARAARCLLEQVQACF 93 Q D + L A F Sbjct: 61 ---VVQGDQDDQVIMELALNGAYATF 83 >3S8M-A nrPDB Length = 422 Score = 31.3 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 28/97 (28%), Gaps = 8/97 (8%) Query: 12 ALALVTGAGSGIGRA--VSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 LV GA SG G A ++ G GA ++ G S Sbjct: 62 KKVLVIGASSGYGLASRITAAF-GFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKA 120 Query: 70 AA-----FQADVSEARAARCLLEQVQACFSRPPSVVV 101 A D A ++E ++ +VV Sbjct: 121 AGLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVV 157 >2EER-A nrPDB Length = 347 Score = 31.3 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 11 SALALVTGAGSGIGR-AVSVRLAGEGATVAACDLDRAAAQETVRL 54 S +V GAG G+G A+ + A GAT+ D+ A + R Sbjct: 171 SKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRA 215 >4BKP-A nrPDB Length = 336 Score = 31.3 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 29/113 (25%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 LVTG +G+A+ ++ +GA G ++ A Sbjct: 26 LVTGGSGLVGKAI-QKVVADGA-----------------------GLPGEDWVFVSSKDA 61 Query: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 D+++ R L E+VQ V+ A + + + D W K + +N Sbjct: 62 DLTDTAQTRALFEKVQPTH-----VIHLAAMVGGLFRNIKYNLDFWRKNVHMN 109 >4J6F-A nrPDB Length = 382 Score = 31.3 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 17/39 (43%), Gaps = 1/39 (2%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAA 48 LVTGA G+G A+ GA +A + AA Sbjct: 207 GETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAA 245 >5OCM-A nrPDB Length = 291 Score = 31.3 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 26/80 (32%), Gaps = 2/80 (2%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAA 82 +G+A++ +G + A + S VS+ A Sbjct: 14 MGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVVVCVSDHAAV 73 Query: 83 RCLLEQVQACFSRPPSVVVS 102 R +L+ + + V+V+ Sbjct: 74 RAVLDPLGDVLAGR--VLVN 91 >4WLE-A nrPDB Length = 340 Score = 31.3 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 45/144 (31%), Gaps = 34/144 (23%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKE 62 S + + + +A V GA GIG+ +S+ L + Sbjct: 19 SHMSAQNNAKVA-VLGASGGIGQPLSLLL---------------------KNSPLVSRLT 56 Query: 63 GPPRGNHAAFQADVSEARAARCLL-----EQVQACFSRPPSVVVSCAGITQDEFLLHMSE 117 + AD+S + EQ+ C + VVV AG+ + + Sbjct: 57 LYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCL-KGCDVVVIPAGVPRKPGMTR--- 112 Query: 118 DDWDKVIAVNLKGTFLVTQAAAQA 141 D + N +T A AQ Sbjct: 113 ---DDLFNTNATIVATLTAACAQH 133 >5UZH-A nrPDB Length = 345 Score = 30.9 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 17/120 (14%), Positives = 40/120 (33%), Gaps = 14/120 (11%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 S +AL+TG G ++ L +G V + R ++ + + Sbjct: 1 SKVALITGITGQDGSYLAEFLLEKGYMV--YGIIRRSSSFNTGRVEHLYKDIHITKAKFK 58 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 D+++ ++ +++ P + + A + + M E N+ G Sbjct: 59 LLYGDLTDTGNLISIIAKIK------PDEIYNLAAQSHVKVSFEMPE------YTANVDG 106 >3H6N-A nrPDB Length = 127 Score = 30.9 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 21/48 (43%), Gaps = 2/48 (4%) Query: 201 FIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 + T +V +K+++ + +P EDV + + AS YI Sbjct: 23 AMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDV--DLEWFASSTQSYI 68 >1RPN-A nrPDB Length = 335 Score = 30.9 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATV-AACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 ALVTG G ++ L +G V + + +R LG G + Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYED----- 69 Query: 71 AFQADVSEARAARCLLEQVQ 90 D+++A + + + + Q Sbjct: 70 ---GDMADACSVQRAVIKAQ 86 >3DC2-A nrPDB Length = 529 Score = 30.9 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 38/94 (40%), Gaps = 3/94 (3%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 V G G IG+ V+ R+A GA V A D + A+ + + R + Sbjct: 142 GKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFI 200 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCA 104 + + + L+++ ++P ++V+ A Sbjct: 201 SVH--LPKTPETAGLIDKEALAKTKPGVIIVNAA 232 >5TEN-A nrPDB Length = 269 Score = 30.9 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%) Query: 18 GAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVS 77 G G+G A++ + + + VA + + T +G + G G H A AD+ Sbjct: 165 GTAIGMGEAIAGAMGNKLSDVAVYAREGITGERTKDEIGFATIRAGDIVGEHTAMFADIG 224 Query: 78 EARAA 82 E Sbjct: 225 ERVEI 229 >4PZE-A nrPDB Length = 284 Score = 30.6 bits (68), Expect = 0.64, Method: Composition-based stats. Identities = 33/191 (17%), Positives = 67/191 (35%), Gaps = 19/191 (9%) Query: 19 AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSE 78 +G ++ A G V D+ AA Q+ V + + A +A Sbjct: 10 GAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEADKASALA 69 Query: 79 ARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL-----KGTFL 133 + ++A +V+ A D + + D ++ N+ + Sbjct: 70 RIKGSTSYDDLKAT-----DIVIEAATENYDLKVKILK--QIDGIVGENVIIASNTSSIS 122 Query: 134 VTQAAAQALVSNGCRG-SIINISSIVGKVGNV-GQTNYAASKAGVIGLTQTAARELGRHG 191 +T+ AA ++ G N ++ V + G + A V L++ +LG++ Sbjct: 123 ITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSK----QLGKYP 178 Query: 192 IRCNSVLPGFI 202 I + PGF+ Sbjct: 179 ITVKN-SPGFV 188 >2HK7-A nrPDB Length = 269 Score = 30.6 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 24/70 (34%), Gaps = 1/70 (1%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 ++ LV GAG G RAV L EGA V + + A + + + Sbjct: 121 VKEKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVID 179 Query: 69 HAAFQADVSE 78 + + Sbjct: 180 KVQVIVNTTS 189 >5V6R-A nrPDB Length = 587 Score = 30.6 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 2/48 (4%) Query: 201 FIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYI 248 + T +V +K+++ + +P EDV + + AS Y+ Sbjct: 236 AMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDV--DLEWFASSTQSYV 281 >1XDW-A nrPDB Length = 331 Score = 30.2 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 36/103 (34%), Gaps = 5/103 (4%) Query: 2 ASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSK 61 A +R+ V G G IGR + G GATV D+ E Sbjct: 137 AFMFSKEVRNCTVGVVGLGR-IGRVAAQIFHGMGATVIGEDVFEIKGIE--DYCTQVSLD 193 Query: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCA 104 E + + A + A + ++ + +++V+CA Sbjct: 194 EVLEKSDIITIHAPYIKENGAVVTRDFLKKM--KDGAILVNCA 234 >1EDZ-A nrPDB Length = 320 Score = 30.2 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 7 NRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDR 45 NRL +V +GR ++ LA +GATV + D++ Sbjct: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNN 211 >1ZDL-A nrPDB Length = 517 Score = 30.2 bits (67), Expect = 0.99, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP 58 LV G GSG G A + A G VA D + + T LGG Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGT 78 >2DFV-A nrPDB Length = 347 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 27/83 (32%), Gaps = 6/83 (7%) Query: 7 NRLRSALALVTGAG--SGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 + L+TGAG +G AV+ GA +E + +G P Sbjct: 163 GPISGKSVLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSDFRRELAKKVG-ADYVINP 218 Query: 65 PRGNHAAFQADVSEARAARCLLE 87 + D+++ LE Sbjct: 219 FEEDVVKEVMDITDGNGVDVFLE 241 >4E0B-A nrPDB Length = 313 Score = 30.2 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 21/35 (60%), Gaps = 4/35 (11%) Query: 12 ALALVTGAGSGIGRAVSVRLAG---EGATVAACDL 43 +A++ GA GIG+A+++ L G+ +A D+ Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDI 38 >4KTT-E nrPDB Length = 327 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQ-ETVRLLGGPG 59 + LVTGA +GRAV C RA + E V LL Sbjct: 21 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNA 70 >4J0E-A nrPDB Length = 320 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG 57 +A+V +G ++ A G V D+++ A ++ + Sbjct: 17 VAIV--GSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQ 59 >4KDR-A nrPDB Length = 223 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 30/92 (32%), Gaps = 20/92 (21%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L L G G GI ++ +A EGATV D +G + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLD------------MGFEPLQVAKLHAL 105 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVV 100 + Q D + +E+ A + VV Sbjct: 106 ESGIQVDY-----VQETVEEHAAKHAGQYDVV 132 >1K20-A nrPDB Length = 310 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 20/144 (13%), Positives = 42/144 (29%), Gaps = 23/144 (15%) Query: 25 RAVSVRLAG-EGATV---------AACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 +A++ LA G + A +L +A+E + + G Sbjct: 164 KAIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRVAQVNTV 223 Query: 75 DVSEARAARCLLEQVQAC----------FSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 D++E + +E ++ S + I + E ++ V+ Sbjct: 224 DIAEVLERQAEIEAAIEKAIADNGYSDFVLMITDIINSNSEILAIGSNMDKVEAAFNFVL 283 Query: 125 AVN---LKGTFLVTQAAAQALVSN 145 N L G + L + Sbjct: 284 ENNHAFLAGAVSRKKQVVPQLTES 307 >1JAY-A nrPDB Length = 212 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDL 43 +AL+ G +G+ +++RLA G + Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSR 32 >4YZP-A nrPDB Length = 536 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 35/114 (30%), Gaps = 12/114 (10%) Query: 29 VRLAGEGATVAACDLDRAAAQETVRLLG--------GPGSKEGPPRGNHAAFQADVSEAR 80 + EG V + A E + P ++ Q D +E + Sbjct: 258 EKFVREGYPVIIGEYGTLGANEKHSKWLYHDTFVRLAHKYQMVPMWWDNGNDQFDRAERQ 317 Query: 81 AARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 +++++ R V A I + + + D+ + + L G L Sbjct: 318 WRDPVVKEIVIQAGRG----VPNAIIKPADLFIKKGQSISDQTVDIQLNGNVLT 367 >4UUP-A nrPDB Length = 341 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 31/105 (29%), Gaps = 8/105 (7%) Query: 14 ALVTGAGSGIGRAVSVRLAGE---GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 L+TGA IG A++ R+A G L ++ Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 71 AFQADVSEARAARCLLEQVQACFSRPP-----SVVVSCAGITQDE 110 D E + + F R P ++ AGI + + Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQ 111 >4KDC-A nrPDB Length = 246 Score = 29.8 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 30/92 (32%), Gaps = 20/92 (21%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 L L G G GI ++ +A EGATV D +G + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLD------------MGFEPLQVAKLHAL 105 Query: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVV 100 + Q D + +E+ A + VV Sbjct: 106 ESGIQVDY-----VQETVEEHAAKHAGQYDVV 132 >6APE-A nrPDB Length = 298 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 20/40 (50%) Query: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL 43 ++ + GA + IG+ +S+ + GA+V+ C + Sbjct: 163 HYHIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHI 202 >1ZCJ-A nrPDB Length = 463 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 18/42 (42%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 +GR +++ A G +V A + D +++ KE Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEAS 89 >4B4V-A nrPDB Length = 303 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 20/46 (43%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRL 54 + A+V G + +G+ +++ L ATV C E V+ Sbjct: 177 IAGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQ 222 >3QFF-A nrPDB Length = 389 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 21/54 (38%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADV 76 +GR +++ G +A D + + V + S + H A +DV Sbjct: 25 LGRMMALAAKEMGYKIAVLDPTKNSPCAQVADIEIVASYDDLKAIQHLAEISDV 78 >4WOK-A nrPDB Length = 336 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 20/53 (37%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVR 53 MA + + + LV G IG + LAG+G D Q VR Sbjct: 1 MAHHHHHHMSANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVR 53 >1JPH-A nrPDB Length = 388 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 26/87 (29%), Gaps = 6/87 (6%) Query: 29 VRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQ 88 LA G V D A ++ +G + +G + L++Q Sbjct: 291 EELAQAGYEVVGLDWT-VAPKKARECVGKTVTLQGNLDPCALY-----ASEEEIGQLVKQ 344 Query: 89 VQACFSRPPSVVVSCAGITQDEFLLHM 115 + F + G+ D H+ Sbjct: 345 MLDDFGPHRYIANLGHGLYPDMDPEHV 371 >2C54-A nrPDB Length = 379 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 16/32 (50%) Query: 16 VTGAGSGIGRAVSVRLAGEGATVAACDLDRAA 47 +TGAG I ++ RL EG V A D + Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKNE 65 >4D3S-A nrPDB Length = 293 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 9/73 (12%), Positives = 22/73 (30%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAA 82 +G+A++ L G + + +A A+ ++E Sbjct: 19 MGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVLLSLTEHAVM 78 Query: 83 RCLLEQVQACFSR 95 +LE ++ Sbjct: 79 YRVLEGAESDLKG 91 >3A31-A nrPDB Length = 471 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 22/85 (25%), Gaps = 3/85 (3%) Query: 26 AVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ---ADVSEARAA 82 +++ L +G VA + VR + + DV Sbjct: 362 SIAKGLLDKGFRVAVKGSSKTGLSSDVRHIESTAKPAVNVFIGAKEVREKVLDVRVFDLE 421 Query: 83 RCLLEQVQACFSRPPSVVVSCAGIT 107 ++ + V + A + Sbjct: 422 SMKRRRLAIAYGDAADAVENLAAVA 446 >3ZWA-A nrPDB Length = 742 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 18/42 (42%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 +GR +++ A G +V A + D +++ KE Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEAS 368 >5KIA-A nrPDB Length = 351 Score = 29.0 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 36/118 (30%), Gaps = 2/118 (1%) Query: 8 RLRSALALVTGAGSGIG-RAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 L L+TGAG IG AV++ V D++ R+ Sbjct: 169 NLVGEDVLITGAGP-IGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRES 227 Query: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVI 124 ++E + V + F+ + + + DW++VI Sbjct: 228 LRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVI 285 >6HRD-A nrPDB Length = 317 Score = 29.0 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 35/99 (35%), Gaps = 13/99 (13%) Query: 3 SQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRA----------AAQETV 52 S + + ++ + +V GAG +G ++ A G V + A + E Sbjct: 19 SHMSDAIQ-RVGVV-GAGQ-MGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERA 75 Query: 53 RLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQA 91 G +E F D+++ + ++E V Sbjct: 76 VSAGKVTERERDRALGLLTFTTDLNDLSDRQLVIEAVVE 114 >4XGU-A nrPDB Length = 424 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 12/77 (15%) Query: 120 WDKVI-AVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178 W+ +I NLK + AA L IIN++ ++ G G G Sbjct: 136 WENLIYDSNLKNEVMSYVAALARLSEKHVNTKIINVNRLILLTGPPGT--------GKTS 187 Query: 179 LTQTAARELGRHGIRCN 195 L + A+ L IR N Sbjct: 188 LCKGLAQHLS---IRMN 201 >1F14-A nrPDB Length = 310 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 26/88 (29%), Gaps = 2/88 (2%) Query: 16 VTGAGSGI-GRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 VT G G+ G ++ A G TV D ++ + + K + Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKAG 77 Query: 75 DVSEARAARCLLEQVQAC-FSRPPSVVV 101 D + + A +VV Sbjct: 78 DECVEKTLSTIATSTDAASVVHSTDLVV 105 >6H0D-A nrPDB Length = 403 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 23/51 (45%), Gaps = 4/51 (7%) Query: 13 LALVTGAGSG----IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG 59 +AL+ + G + +A++ + G V A + + + A+E +G Sbjct: 258 VALIYASAYGNTSTLAQAIARGITKAGVAVTAINAETSNAEEIKEAIGKSA 308 >5GXF-A nrPDB Length = 330 Score = 28.6 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 LVTGA G+G + LA G VAA ET L G+ + R Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAV----TGRPETADYLTSLGATQIVAR 201 >4B4O-A nrPDB Length = 298 Score = 28.6 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 17/58 (29%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 LV G IG A++ L G V + T L G N A Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAG 60 >4J90-A nrPDB Length = 222 Score = 28.6 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 20/53 (37%), Gaps = 9/53 (16%) Query: 6 QNRLRSA-LALVTGAGSGIGR---AVSVRLAGEGATVAACDLDRAAAQETVRL 54 R+++ A++ G+GR ++ L G V A D++ Sbjct: 1 MGRIKNKQFAVI-----GLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASY 48 >2Q4B-A nrPDB Length = 253 Score = 28.6 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 25/80 (31%), Gaps = 12/80 (15%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 LVTGA G+ + L + + + L + G Sbjct: 5 PTVLVTGASGRTGQ------------IVYKKLKEGSDKFVAKGLVRSAQGKEKIGGEADV 52 Query: 72 FQADVSEARAARCLLEQVQA 91 F D+++A + + + A Sbjct: 53 FIGDITDADSINPAFQGIDA 72 >3R9I-A nrPDB Length = 260 Score = 28.6 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 16/37 (43%), Gaps = 5/37 (13%) Query: 12 ALALVTGAGSGIGR-----AVSVRLAGEGATVAACDL 43 + +VT G+G+ A++ LA +G D Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDF 39 >6C6P-A nrPDB Length = 458 Score = 28.2 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPG 59 ++ GAG +G A++ L+ +G V + D V PG Sbjct: 10 VIIVGAGV-LGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPG 54 >6GAR-A nrPDB Length = 349 Score = 28.2 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 34/118 (28%), Gaps = 8/118 (6%) Query: 7 NRLRSALALVTGAGSGIGRAV--SVRLAGEGATVAACDLDRA--AAQETVRLLGGPGSKE 62 R + +++G G+ AV + L V + V+ L ++ Sbjct: 149 KRFKGKTVIISGGGNS---AVDWANELEPIAKKVYVTYRKEELSGHEAQVKQLMNSSAEC 205 Query: 63 GPPRGNHAAFQADVSEA-RAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDD 119 D EA + P V+ G +D LL SE D Sbjct: 206 FFNTSITKLIAGDNHEAIEYVELTNHETGEVSHLPIDEVIINHGYERDITLLENSELD 263 >4A5O-A nrPDB Length = 286 Score = 28.2 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 6/70 (8%) Query: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDL------DRAAAQETVRLLGGPGSKEGPPRG 67 A+V GA + +GR +++ L G TV D + + V + G Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSRADLVVVAAGKPGLVKGEWI 223 Query: 68 NHAAFQADVS 77 A DV Sbjct: 224 KEGAIVIDVG 233 >2YQ5-A nrPDB Length = 343 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 9/21 (42%), Positives = 12/21 (57%) Query: 23 IGRAVSVRLAGEGATVAACDL 43 IG AV+ + GA V A D+ Sbjct: 159 IGSAVAEIFSAMGAKVIAYDV 179 >4B3F-X nrPDB Length = 646 Score = 27.9 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 55/165 (33%), Gaps = 15/165 (9%) Query: 31 LAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQ 90 LA + D+ + Q V+ +E N + R +LE + Sbjct: 282 LARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLT 341 Query: 91 ACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGS 150 + V+ + G + D L + E +D V+ ++ L L + C Sbjct: 342 SA----NVVLATNTGASADGPLKLLPESYFDVVV-IDECAQALEASCWIPLLKARKC--- 393 Query: 151 IINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELG-RHGIRC 194 ++ ++ ++ KA + GL+ + L +G R Sbjct: 394 --ILAGDHKQLPPTTVSH----KAALAGLSLSLMERLAEEYGARV 432 >1YXY-A nrPDB Length = 234 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 7/56 (12%) Query: 142 LVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSV 197 L+ G I+ G+ Y+ + G++ L AA+E G GIR NSV Sbjct: 10 LMEQLKGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >2OHJ-A nrPDB Length = 404 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 16/37 (43%), Gaps = 3/37 (8%) Query: 6 QNRLRSALALVTGAGSGIGRAVS---VRLAGEGATVA 39 NR + ALV G+ G G A LA G VA Sbjct: 338 FNRTLTRKALVFGSMGGNGGATGTMKELLAEAGFDVA 374 >4GBJ-A nrPDB Length = 297 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 7/74 (9%), Positives = 22/74 (29%), Gaps = 1/74 (1%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAA 82 +G ++ L G + + + A+ +L + +++ A Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVFSVLADDAAV 75 Query: 83 RCLLE-QVQACFSR 95 L ++ + Sbjct: 76 EELFSMELVEKLGK 89 >1IE3-A nrPDB Length = 312 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 36/101 (35%), Gaps = 7/101 (6%) Query: 12 ALALVTGAGSGIGRAVSVRLAGE---GATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 +A V GA GIG+A+++ L + G+ ++ D+ V L P + + Sbjct: 2 KVA-VLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSG 60 Query: 69 HAAFQADVSEARAARCLLEQVQACFS-RPPSVVVSCAGITQ 108 A A E + V + AGI + Sbjct: 61 EDATPA--LEGADVVLISAGVARKPGMDRSDLFNVNAGIVK 99 >4MIE-A nrPDB Length = 351 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 7/47 (14%) Query: 12 ALALV-TGAGSGIGRAVSVRL--AGEGATVA-ACDLDRAAAQETVRL 54 + ++ TGA +GRA RL GA V D+D AA+ VR Sbjct: 16 KVGVIGTGA---MGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRD 59 >3HDH-A nrPDB Length = 302 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 26/88 (29%), Gaps = 2/88 (2%) Query: 16 VTGAGSGI-GRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 VT G G+ G ++ A G TV D ++ + + K + Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKAG 77 Query: 75 DVSEARAARCLLEQVQAC-FSRPPSVVV 101 D + + A +VV Sbjct: 78 DEFVEKTLSSISTSTDAASVVHSTDLVV 105 >3L9K-A nrPDB Length = 97 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 21/46 (45%) Query: 80 RAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 + L+++Q+ ++VV+ GI L + + + +++ Sbjct: 3 QEVEETLKRIQSHKGVVGTIVVNNEGIPVKSTLDNTTTVQYAGLMS 48 >3DMF-A nrPDB Length = 381 Score = 27.9 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 37/110 (33%), Gaps = 14/110 (12%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 +R L GAG G A+++ LA GA V + D A+ + L K Sbjct: 232 VRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQ----- 283 Query: 69 HAAFQADVSEARAARCLLEQVQA----CFSRPPSVVVSCAGITQDEFLLH 114 A +DV EA + + + V+ A + L Sbjct: 284 --ALHSDVDEALTEEARFDIIVTNPPFHVGGAVILDVAQAFVNVAAARLR 331 >5NUE-A nrPDB Length = 332 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 22/67 (32%), Gaps = 5/67 (7%) Query: 14 ALVTGAGSGIGRAVSVRLAG---EGAT--VAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 LVTGA IG A+ +A GA V LD A E + + P Sbjct: 8 VLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLK 67 Query: 69 HAAFQAD 75 D Sbjct: 68 GVVATTD 74 >3K4W-A nrPDB Length = 291 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 15/65 (23%) Query: 155 SSIVGKVGNVGQTNYAASKA---------GVIGLTQTAAR----ELGRHGIRCNSVLPGF 201 SS++G V N A +KA + T+ A E+ GIR ++ PG Sbjct: 71 SSVLGSVSNADVA--AVAKAYPDKFHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGV 128 Query: 202 IATPM 206 ATPM Sbjct: 129 WATPM 133 >1MLD-A nrPDB Length = 314 Score = 27.5 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 41/135 (30%), Gaps = 34/135 (25%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +A V GA GIG+ +S+ L + + Sbjct: 2 KVA-VLGASGGIGQPLSLLL---------------------KNSPLVSRLTLYDIAHTPG 39 Query: 72 FQADVSEARAARCLL-----EQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 AD+S + EQ+ C + VVV AG+ + + D + Sbjct: 40 VAADLSHIETRATVKGYLGPEQLPDCL-KGCDVVVIPAGVPRKPGMTR------DDLFNT 92 Query: 127 NLKGTFLVTQAAAQA 141 N +T A AQ Sbjct: 93 NATIVATLTAACAQH 107 >2BC1-A nrPDB Length = 490 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 56/175 (32%), Gaps = 23/175 (13%) Query: 12 ALALVTGAGSGIGRAVSVRLAGEGATVAACD-LDRAAAQETVRLLGGPGSKEGPPRGNHA 70 +A+V IG ++ +G V D +D A R L +K G Sbjct: 196 RVAVV--GAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQL 253 Query: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130 AF V E + + + +V+ G + L + D + G Sbjct: 254 AFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFR-------NG 306 Query: 131 TFLVTQA---AAQALVSNGCRGSI----------INISSIVGKVGNVGQTNYAAS 172 FLV + + + + G +I I ++S + G V N + Sbjct: 307 AFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGT 361 >4EJ0-A nrPDB Length = 342 Score = 27.5 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 20/134 (14%), Positives = 38/134 (28%), Gaps = 29/134 (21%) Query: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 +VTGA IG + L G T + A + L Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNL-----------------VDC 58 Query: 75 DVSEARAARCLLEQVQA-CFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 ++ + +E+ F + + + E D ++ N F Sbjct: 59 EIDDYLDKTEFVERFARGDFGKVR-------AVFHEGACSDTMETDGRYMMDNN----FR 107 Query: 134 VTQAAAQALVSNGC 147 ++A A ++ G Sbjct: 108 YSRAVLDACLAQGA 121 >4Z6K-A nrPDB Length = 346 Score = 27.5 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 52/145 (35%), Gaps = 16/145 (11%) Query: 15 LVTGAGSGIGRAVSVRLA-GEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 +V G+G ++V+ A G VAA D+D + LG + Q Sbjct: 168 VVISGIGGLG-HMAVQYAIAMGLNVAAVDIDDDKL-AFAKKLGAKVTVNAKNTDPAEYLQ 225 Query: 74 ADVSEARAA------RCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA-V 126 ++ A A +Q + R ++V + G+ +D V+ + Sbjct: 226 KEIGGAHGALVTAVSAKAFDQALSMLRRGGTLVCN--GLPPG----DFPVSIFDTVLNGI 279 Query: 127 NLKGTFLVTQAAAQALVSNGCRGSI 151 ++G+ + T+ Q + G + Sbjct: 280 TIRGSIVGTRLDLQESLDMAAAGKV 304 >3D64-A nrPDB Length = 494 Score = 27.5 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRL 54 + +A+V G G +G+ + L G GATV ++D A + Sbjct: 275 IAGKIAVVAGYGD-VGKGCAQSLRGLGATVWVTEIDPICALQAAME 319 >6BMQ-A nrPDB Length = 523 Score = 27.5 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 11/37 (29%) Query: 33 GEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69 +GA V + A E +GG H Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKALSLTDLDNYH 421 >5BUT-A nrPDB Length = 288 Score = 27.5 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRL 54 R+++ V G G G ++ L G V A D++ Sbjct: 1 MGRIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNAYASY 48 Score = 27.1 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 13/36 (36%), Gaps = 3/36 (8%) Query: 22 GIGR---AVSVRLAGEGATVAACDLDRAAAQETVRL 54 G+GR ++ L G V A D++ Sbjct: 155 GLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY 190 >3K6J-A nrPDB Length = 460 Score = 27.5 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 9/97 (9%), Positives = 30/97 (30%), Gaps = 9/97 (9%) Query: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG-------PGSKEGPP 65 +A++ G +G+A+++ G + ++ + ++ K Sbjct: 57 VAIIGGGT--MGKAMAICFGLAGIETFLVVRNEQRCKQELEVMYAREKSFKRLNDKRIEK 114 Query: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVS 102 + +D + ++E V + + Sbjct: 115 INANLKITSDFHKLSNCDLIVESVIEDMKLKKELFAN 151 >2HMT-A nrPDB Length = 144 Score = 27.1 bits (59), Expect = 7.3, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRL 54 R+++ V G G G ++ L G V A D++ Sbjct: 1 MGRIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNAYASY 48 >4WEQ-A nrPDB Length = 341 Score = 27.1 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 15/49 (30%), Gaps = 1/49 (2%) Query: 23 IGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAA 71 +G+ + +LA G V + E V G R + Sbjct: 172 LGQDAARKLAAMGFKVIGWSRSKR-VIEGVETYDAAGLDAFLGRTDFLV 219 >1PGJ-A nrPDB Length = 478 Score = 27.1 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 33/85 (38%), Gaps = 11/85 (12%) Query: 27 VSVRLAGEGATVAACDLDRAAAQETVRL-LGGPGSKEGPPRGNHAAFQADVSEA------ 79 +++ +A +G VA + + ++E ++ P + AF A + + Sbjct: 16 LALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALIL 75 Query: 80 ----RAARCLLEQVQACFSRPPSVV 100 A +EQ++ F + +V Sbjct: 76 VQAGAATDSTIEQLKKVFEKGDILV 100 >6CAU-A nrPDB Length = 472 Score = 26.7 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 25/77 (32%), Gaps = 11/77 (14%) Query: 22 GIGRA----VSVRLAGEGATVAACDLDRAAAQETVRL------LGGPGSKEGPPRGNHAA 71 GIG A ++ LA +G ++ D+ + + + +G + Sbjct: 19 GIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEENGIKVYIGHEAENIKNANVLVVS 78 Query: 72 FQADVSEARAARCLLEQ 88 D + +EQ Sbjct: 79 TAIDPENPE-VKAAIEQ 94 >3L07-A nrPDB Length = 285 Score = 26.7 bits (58), Expect = 9.8, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 20/43 (46%) Query: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL 43 M + + A A+V GA + +G+ VS L ATV C Sbjct: 151 MLREYGIKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHR 193 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.159 0.472 Lambda K H 0.267 0.0486 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,701,989 Number of Sequences: 36641 Number of extensions: 538862 Number of successful extensions: 3481 Number of sequences better than 10.0: 392 Number of HSP's better than 10.0 without gapping: 393 Number of HSP's successfully gapped in prelim test: 177 Number of HSP's that attempted gapping in prelim test: 2134 Number of HSP's gapped (non-prelim): 622 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.1 bits)