BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8VXY9 (476 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4PXB-A nrPDB 862 0.0 3N5F-A nrPDB 249 2e-66 5TP4-A nrPDB 214 5e-56 5THW-A nrPDB 213 2e-55 4WJB-A nrPDB 200 1e-51 5I4M-A nrPDB 200 1e-51 1Z2L-A nrPDB 197 6e-51 2V8D-A nrPDB 167 1e-41 6C0D-A nrPDB 142 4e-34 1QQ9-A nrPDB 40 0.003 4QI7-A nrPDB 36 0.035 4MCR-A nrPDB 35 0.10 1LFW-A nrPDB 33 0.24 6AIT-A nrPDB 30 3.4 3MRU-A nrPDB 28 7.5 4ECM-A nrPDB 28 9.4 >4PXB-A nrPDB Length = 430 Score = 862 bits (2226), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/427 (99%), Positives = 426/427 (99%) Query: 50 FGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGL 109 FGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGL Sbjct: 4 FGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGL 63 Query: 110 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGF 169 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGF Sbjct: 64 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGF 123 Query: 170 KPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGY 229 KPKRSLEIILFTS EPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGY Sbjct: 124 KPKRSLEIILFTSAEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGY 183 Query: 230 AEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGG 289 AEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGG Sbjct: 184 AEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGG 243 Query: 290 HAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLE 349 HAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLE Sbjct: 244 HAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLE 303 Query: 350 IDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAAT 409 IDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAAT Sbjct: 304 IDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAAT 363 Query: 410 ELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLT 469 ELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLT Sbjct: 364 ELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLT 423 Query: 470 LAKLSLD 476 LAKLSLD Sbjct: 424 LAKLSLD 430 >3N5F-A nrPDB Length = 408 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 155/410 (37%), Positives = 228/410 (55%), Gaps = 11/410 (2%) Query: 66 LQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDG 125 L ++ EL PS VTR+ +T ++ A+ V + M AGL V EDA GN+ G+ +G Sbjct: 7 LWQRLMELGEVGKQPSGGVTRLSFTAEERRAKDLVASYMREAGLFVYEDAAGNLIGRKEG 66 Query: 126 LEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEP 185 P+ V GSH+D++ G +DG +GVL +E + + G +E++ FT EE Sbjct: 67 TNPDATVVLVGSHLDSVYNGGCFDGPLGVLAGVEVVQTMNEHGVVTHHPIEVVAFTDEEG 126 Query: 186 TRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKG 245 RF +GSR +AG+ EAL+ D + +S EA + AG D+ L K G Sbjct: 127 ARFRFGMIGSRAMAGTLP-PEALECR--DAEGISLAEAMKQAGLDPDR---LPQAARKPG 180 Query: 246 SYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLA 305 + A++ELHIEQG +LE+ GL +G+VT IA +K EG HAGA M R D A Sbjct: 181 TVKAYVELHIEQGRVLEETGLPVGIVTGIAGLIWVKFTIEGKAEHAGATPMSLRRDPMAA 240 Query: 306 AAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVIK 365 AA++ + +E+ + + TVGTVG L ++PG IN IP + +D RD+ R+ V K Sbjct: 241 AAQIIIVIEEEARRTGT--TVGTVGQLHVYPGGINVIPERVEFVLDLRDLKAEVRDQVWK 298 Query: 366 KIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATE-LNLSHKMMISRAYH 424 I A TIAK+R V+++ ++ P SD+ +K+ AEAA + L + S A H Sbjct: 299 AIAVRAETIAKERNVRVTTERLQEMPPVLCSDE--VKRAAEAACQKLGYPSFWLPSGAAH 356 Query: 425 DSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKLS 474 DS+ +A I P+GMIF+ G SH P E+S+ ED A G +VL T+ +L+ Sbjct: 357 DSVQLAPICPIGMIFVRSQDGVSHSPAEWSTKEDCAAGAEVLYHTVWQLA 406 >5TP4-A nrPDB Length = 431 Score = 214 bits (546), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 127/408 (31%), Positives = 203/408 (49%), Gaps = 12/408 (2%) Query: 59 LSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGN 118 L +D L + +++ P V R+ TD D R AG+TV DAVGN Sbjct: 13 LEIDGARLWRSLADMARIGATPRGGVRRLALTDDDRRGRDLFAQWCRDAGMTVSVDAVGN 72 Query: 119 IFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEII 178 +F + DG + V GSH+D P G++DGV GVL +E + L +G + LEI+ Sbjct: 73 LFARRDGADAQAAPVLIGSHLDTQPEGGRFDGVYGVLAGLEVVRTLNDAGIVTDKPLEIV 132 Query: 179 LFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLS 238 +T+EE RF + LGS + G+ L +AL D + ++ A + G Sbjct: 133 SWTNEEGARFAPAMLGSAVFTGALPLDDALARQ--DAEGITLGAALDACG--------CR 182 Query: 239 SVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPY 298 G+ A+ E HIEQGP+LE G IG+VT A L V G HAG MPY Sbjct: 183 GTRAPGGAVDAYFEAHIEQGPVLEANGTTIGIVTGGQAIRWLDVRVTGVAAHAGTTPMPY 242 Query: 299 RNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEA 358 R DA A+A++AL +E+ ++ + + T+G + + N+I +D R D+A Sbjct: 243 RKDAYFASAQMALELER-IVAGHAPRGLATIGQAGIRNASRNTIAGDVTFTVDLRHHDDA 301 Query: 359 RRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKMM 418 + + + + ++++ +A R V+++ + P D+ ++ +A AA +++ + Sbjct: 302 QVDAMERALRDACARVAAARGVQVA-IDTCWRSPATPFDRGCVELVARAAEAFGYTNERI 360 Query: 419 ISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVL 466 +S A HD++ +AR P M+FIPC G SH E + P+D+ G VL Sbjct: 361 VSGAGHDAILLARRVPTAMVFIPCVDGLSHNEAEDALPDDVTRGTNVL 408 >5THW-A nrPDB Length = 434 Score = 213 bits (541), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 133/409 (32%), Positives = 203/409 (49%), Gaps = 11/409 (2%) Query: 58 SLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVG 117 S+ VD L N + E++ P V R+ TD D + R + AG TV D +G Sbjct: 24 SIKVDGKRLWNSLMEMAKIGATPKGGVCRLALTDLDKAGRDLIVRWAKEAGCTVTVDTMG 83 Query: 118 NIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEI 177 N+F + G + V TGSH D+ P G++DG+ GVLG +E I L G + + +E+ Sbjct: 84 NVFMRRAGRVADAAPVVTGSHADSQPTGGRFDGIYGVLGGLEVIRSLNDHGIETEHPIEV 143 Query: 178 ILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDL 237 +++T+EE +RF + + S + AG L L VDG+ + E + GYA D Sbjct: 144 VIWTNEEGSRFAPAMVASGVFAGVFTLEYGLSRKDVDGKTIG--EELQRIGYAGD----- 196 Query: 238 SSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMP 297 V A ELHIEQGPILE E IGVVT ++ F G HAG MP Sbjct: 197 --VPCGGRPLHAAFELHIEQGPILEAERKTIGVVTDAQGQRWYEITFTGQEAHAGPTPMP 254 Query: 298 YRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDE 357 R DA L A+ + V + L+ TVG++++HP + N IP + +D R D+ Sbjct: 255 RRRDALLGASRVVDLVNRIGLDHAPFGCA-TVGMMQVHPNSRNVIPGRVFFTVDFRHPDD 313 Query: 358 ARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKM 417 A + +++ IA ++ + +I P A D ++ + EAA H+ Sbjct: 314 AVLAQMDAALRDGVARIAADIGLETALEQIFYYKPVAF-DPACVQAVREAAERFGYPHRD 372 Query: 418 MISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVL 466 ++S A HD+ ++A+++P M+F+PC G SH E ++PE + G VL Sbjct: 373 IVSGAGHDACYLAQVAPTSMVFVPCVDGISHNEVEDATPEWIEAGANVL 421 >4WJB-A nrPDB Length = 424 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 134/414 (32%), Positives = 201/414 (48%), Gaps = 17/414 (4%) Query: 56 ASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDA 115 AS VD L ++ ++ P V R+ TD D +R AG TVR D Sbjct: 14 ASMPRVDGDRLWASLERMAQIGATPKGGVCRLALTDLDRESRDLFVQWAREAGCTVRVDR 73 Query: 116 VGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSL 175 +GN+F + G P+ V TGSH D+ P G+YDG+ GVLG +E + L + + +R + Sbjct: 74 MGNVFARRAGRRPDAAPVMTGSHADSQPTGGRYDGIYGVLGGLEVVRALNDAAIETERPV 133 Query: 176 EIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDD 235 +++++T+EE +RF + + + + +G L L T DG + E GYA + Sbjct: 134 DVVIWTNEEGSRFAPAMVSAGVFSGVYTLEYGLSRT--DGAGRTIGEELERIGYAGAE-- 189 Query: 236 DLSSVFLKKGSY--FAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGA 293 G Y A ELHIEQG ILE G IGVVTA +V G HAG Sbjct: 190 -------PVGGYPVHAAYELHIEQGAILERAGKTIGVVTAGQGQRWYEVTLTGVDAHAGT 242 Query: 294 VLMPYRNDAGLAAAELALAVEKHVLESE-SIDTVGTVGILELHPGAINSIPSKSHLEIDT 352 M +R DA + AA + VE VL + D TVG++E P + N++P ++ Sbjct: 243 TPMAFRRDALVGAARMISFVE--VLGRRYAPDARATVGMIEARPNSRNTVPGGCFFTVEF 300 Query: 353 RDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELN 412 R D+A + + ++ +A + + +I P + + I + +AA L Sbjct: 301 RHPDDAVLDELDAALRAELARVADETGLGAQIEQIFTYAPVPFAPR-CIDTVRDAARSLG 359 Query: 413 LSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVL 466 LSH ++S A HD+ ++AR++P GMIF+PC G SH E +PE G VL Sbjct: 360 LSHMDIVSGAGHDACYVARVAPTGMIFVPCVDGLSHNEAEAITPEWATAGADVL 413 >5I4M-A nrPDB Length = 434 Score = 200 bits (508), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 132/412 (32%), Positives = 201/412 (48%), Gaps = 11/412 (2%) Query: 55 LASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVRED 114 L +S+ VD L + + E++ P V R+ TD D +AR + AG TV D Sbjct: 21 LDTSIKVDGRRLWDSLMEVAKIGATPKGGVCRLALTDLDKAARDLIVGWAKAAGCTVTVD 80 Query: 115 AVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRS 174 +GN+F + G + V TGSH D+ P G++DG+ GVLG +E I L G + + Sbjct: 81 TMGNVFMRRAGRVADAAPVVTGSHADSQPTGGRFDGIYGVLGGLEVIRSLNDHGIETEHP 140 Query: 175 LEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKD 234 +E++++T+EE +RF + + S + AG L L VDG+ + E GYA D Sbjct: 141 VEVVIWTNEEGSRFAPAMVASGVFAGVFPLEYGLSRKDVDGKTIG--EELARIGYAGDAP 198 Query: 235 DDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAV 294 A ELHIEQGPILE E IGVVT ++ F G HAG Sbjct: 199 -------CGGRKLHAAFELHIEQGPILEAECKTIGVVTDAQGQRWYEITFTGQEAHAGPT 251 Query: 295 LMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRD 354 MP R DA L A+ + V + L+ TVG++++HP + N IP + +D R Sbjct: 252 PMPRRRDALLGASRVVDLVNRIGLDHAPYGCA-TVGMMQVHPNSRNVIPGRVFFTVDFRH 310 Query: 355 IDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLS 414 D+A + +++ IA + + +I P A D + + AA S Sbjct: 311 PDDAVLAKMDAALRDGVARIAADIGLDTALEQIFYYAPIAF-DSACVAAVRAAADRFGYS 369 Query: 415 HKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVL 466 H+ ++S A HD+ ++A+++P M+F+PC G SH E ++P + G VL Sbjct: 370 HRDIVSGAGHDACYLAQVAPTSMVFVPCIDGISHNEIEDATPAWIEAGANVL 421 >1Z2L-A nrPDB Length = 423 Score = 197 bits (502), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 129/411 (31%), Positives = 203/411 (49%), Gaps = 11/411 (2%) Query: 66 LQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDG 125 ++ + LSSF P+ +TR+LY+ + + ++ K MA +GL R D VGN++G+ +G Sbjct: 11 IEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNG 70 Query: 126 LEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEP 185 E V +GSHID + G DG G L A AI+ LK P R++E++ EE Sbjct: 71 TEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEG 130 Query: 186 TRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKG 245 +RF GS+ + G + + D + SF++A ++ G+ ++ + Sbjct: 131 SRFPYVFWGSKNIFGLANPDDV--RNICDAKGNSFVDAMKACGFTLP-----NAPLTPRQ 183 Query: 246 SYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLA 305 AF+ELHIEQG +LE G IGVV AI V G HAG M YR D A Sbjct: 184 DIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYA 243 Query: 306 AAELA-LAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVI 364 + + +VEK + + V T G +E P +N +P K+ ID R D A Sbjct: 244 FSRICHQSVEKAKRMGDPL--VLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFT 301 Query: 365 KKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKMMISRAYH 424 ++++ I + + + ++++P ++ +LV + E L++++M S A H Sbjct: 302 QQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKELV-ATLTELCEREKLNYRVMHSGAGH 360 Query: 425 DSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKLSL 475 D+ A P MIFIP G SH P E ++ D+A GVK L+L L +L+ Sbjct: 361 DAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAW 411 >2V8D-A nrPDB Length = 474 Score = 167 bits (422), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 123/386 (31%), Positives = 192/386 (49%), Gaps = 14/386 (3%) Query: 86 RVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYS 145 R+ T D + R + N G V+ D +GN+F + G P ATGSH+D P + Sbjct: 62 RLAGTALDGAMRDWFTNECESLGCKVKVDKIGNMFAVYPGKNGGKP-TATGSHLDTQPEA 120 Query: 146 GKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELA 205 GKYDG++GVL +E + K + + P + ++++ + E RF SC GS + + L Sbjct: 121 GKYDGILGVLAGLEVLRTFKDNNYVPNYDVCVVVWFNAEGARFARSCTGSSVWSHDLSLE 180 Query: 206 EALK-TTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDE 264 EA +V + + S ++ ++ GY D + K+ A ELHIEQGPILEDE Sbjct: 181 EAYGLMSVGEDKPESVYDSLKNIGYIGD-----TPASYKENEIDAHFELHIEQGPILEDE 235 Query: 265 GLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAVEKHVLESESID 324 IG+VT + A KV G G HAG R DA L ++++ +A + ++ + Sbjct: 236 NKAIGIVTGVQAYNWQKVTVHGVGAHAGTTPWRLRKDALLMSSKMIVAASE---IAQRHN 292 Query: 325 TVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVIKKIQESANTIAK-KRKVKLS 383 + T GI++ P ++N IP + +D R + T++K+ + + K LS Sbjct: 293 GLFTCGIIDAKPYSVNIIPGEVSFTLDFRHPSDDVLATMLKEAAAEFDRLIKINDGGALS 352 Query: 384 EFKIVNQDPPALS-DKLVIKKMAEAA-TELNLSH-KMMISRAYHDSLFMARISPMGMIFI 440 Q PA++ ++ I+ ++ +A + + + S A HDS A P MIFI Sbjct: 353 YESETLQVSPAVNFHEVCIECVSRSAFAQFKKDQVRQIWSGAGHDSCQTAPHVPTSMIFI 412 Query: 441 PCYKGYSHKPEEYSSPEDMANGVKVL 466 P G SH EYSSPE++ NG KVL Sbjct: 413 PSKDGLSHNYYEYSSPEEIENGFKVL 438 >6C0D-A nrPDB Length = 422 Score = 142 bits (357), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 120/406 (29%), Positives = 186/406 (45%), Gaps = 14/406 (3%) Query: 61 VDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIF 120 +D L + + L SF A P V R+ + D+ ARR++ M AGL D VG +F Sbjct: 16 IDPIRLLDDLKTLRSFG-ATGPGVVRLSLSPVDIDARRWLAGRMTDAGLDAAIDGVGTVF 74 Query: 121 GKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILF 180 G+ +P PA+ GSH D P G DG +GV+ +E L + ++++ + Sbjct: 75 GR--SRKPG-PALVIGSHSDTQPTGGWLDGALGVIYGLEIARALGECEATREFAVDVASW 131 Query: 181 TSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSV 240 EE T F S LGSR G + ++L++ + + + +A AG A + V Sbjct: 132 IDEEGT-FS-SFLGSRSFVGDA-IDDSLRSAR-NHEGLLLGDALAQAGLA-----NTPRV 182 Query: 241 FLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRN 300 L + A+LE HIEQG LE IGVVT I ++ F G HAG M R Sbjct: 183 TLDRKRQRAYLEPHIEQGGRLEASAKLIGVVTTIVGIREFQLRFIGQRNHAGTTPMAIRR 242 Query: 301 DAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARR 360 DAG A ++ DTV TVG ++L PG+ + +P K+ L + RD + R Sbjct: 243 DAGAALVAFIAHIDDAFGRLADADTVWTVGRIDLDPGSFSVVPGKAVLHLQFRDANPNRL 302 Query: 361 NTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKM-MI 419 + + + + + V+ + P D + + +A+AA L M M Sbjct: 303 HAMENALVALVDEWNGQHLVRAELIACEGAEEPVTMDAALQQHLAQAADALAPGQWMHMP 362 Query: 420 SRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKV 465 S A HD+ +A+ P M+F+P G SH E ++ + + G +V Sbjct: 363 SGASHDAQVIAQHIPACMLFVPSIGGVSHDFIEDTAEQHIVLGCEV 408 >1QQ9-A nrPDB Length = 284 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 23/175 (13%) Query: 99 YVKNLMALAGLTV------REDAVG-NIFGKWDGLEPNLPAVATGSHIDAIPY-SGKYDG 150 YVK + AG T A G N+ W G +PN +A G+H+D++ +G D Sbjct: 40 YVKAKLDAAGYTTTLQQFTSGGATGYNLIANWPGGDPNKVLMA-GAHLDSVSSGAGINDN 98 Query: 151 VVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKT 210 G +E + R+G++P + L + +EE + +GS+ L A ++ Sbjct: 99 GSGSAAVLETALAVSRAGYQPDKHLRFAWWGAEE-----LGLIGSKFYV--NNLPSADRS 151 Query: 211 TVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEG 265 + N I + + D D + F +YFA L + E +E EG Sbjct: 152 KLAGYLNFDMIGSPNPGYFVYDDDPVIEKTFK---NYFAGLNVPTE----IETEG 199 >4QI7-A nrPDB Length = 806 Score = 36.2 bits (82), Expect = 0.035, Method: Compositional matrix adjust. Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 8/162 (4%) Query: 132 AVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGIS 191 A G + IP + VV G + +L RSG PK LE++ +++ PT S Sbjct: 457 AFRNGGYSGIIPVTNTTGRVVLSAGTFGSAKILLRSGIGPKDQLEVVKASADGPTMVSNS 516 Query: 192 CLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFL 251 L G + TV+ NV+F + ++ + D++ + FA Sbjct: 517 SW-IDLPVGHNLVDHTNTDTVIQHNNVTFYDFYKA--WDNPNTTDMNLYLNGRSGIFAQA 573 Query: 252 ELHIEQGPILEDE--GLDIGVVTAIAAPASLKVEFEGNGGHA 291 +I GP+ +E G D G+V + A ++ FE G+A Sbjct: 574 APNI--GPLFWEEITGAD-GIVRQLHWTARVEGSFETPDGYA 612 >4MCR-A nrPDB Length = 757 Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust. Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 16/112 (14%) Query: 118 NIFGKWDG-LEPNLPAVATGSHIDAIPYSG--KYDGVVGVLGAIEAINVLKRSGFKPKRS 174 N+ G G +EP+ V G H D+ + G G V + + LK+ G++P+R+ Sbjct: 364 NVIGTLRGAVEPDR-YVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRT 422 Query: 175 LEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARS 226 ILF S + FG L GS E AE + ++ + V++I A S Sbjct: 423 ---ILFASWDAAEFG--------LLGSTEWAEE-NSRLLQERGVAYINADSS 462 >1LFW-A nrPDB Length = 470 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 23/37 (62%) Query: 155 LGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGIS 191 L A + +LK +GFKPK+ ++ +L T+EE GI Sbjct: 125 LTAYYGMLLLKEAGFKPKKKIDFVLGTNEETNWVGID 161 >6AIT-A nrPDB Length = 439 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 7/89 (7%) Query: 161 INVLKRSGFKPK-------RSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVV 213 I VL+RSGF P+ + L+ ++S P L LA ++ A ++ VV Sbjct: 166 IQVLQRSGFDPQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVV 225 Query: 214 DGQNVSFIEAARSAGYAEDKDDDLSSVFL 242 ++ AR+ G + L+S L Sbjct: 226 QSSEDFYLAKARTLGMYNSGRNQLTSDLL 254 >3MRU-A nrPDB Length = 490 Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 4/49 (8%) Query: 98 RYVKNLMALAGLTVREDAVGNIFGK---WDGLEPNLPAVATGSHIDAIP 143 +Y+ G VR D GN+F K G+E N V +HID +P Sbjct: 38 QYIVTWATEQGFDVRRDPTGNVFIKKPATPGME-NKKGVVLQAHIDMVP 85 >4ECM-A nrPDB Length = 269 Score = 28.1 bits (61), Expect = 9.4, Method: Compositional matrix adjust. Identities = 17/81 (20%), Positives = 44/81 (54%), Gaps = 7/81 (8%) Query: 172 KRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTT-------VVDGQNVSFIEAA 224 K +++L + ++P RFG++ + +R + +E + K++ + D + S+I+ Sbjct: 150 KEGAKVLLQSVDDPERFGVANIQNRKIIEIEEKPKEPKSSYAVTGIYLYDSKVFSYIKEL 209 Query: 225 RSAGYAEDKDDDLSSVFLKKG 245 + + E + D+++ +LK+G Sbjct: 210 KPSARGELEITDINNWYLKRG 230 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4PXB-A nrPDB 580 e-166 5THW-A nrPDB 574 e-164 5I4M-A nrPDB 557 e-159 4WJB-A nrPDB 528 e-150 1Z2L-A nrPDB 514 e-146 5TP4-A nrPDB 508 e-144 3N5F-A nrPDB 489 e-138 2V8D-A nrPDB 477 e-135 6C0D-A nrPDB 440 e-124 Sequences not found previously or not previously below threshold: 3RZA-A nrPDB 62 4e-10 3GB0-A nrPDB 61 9e-10 5GNE-A nrPDB 52 6e-07 1CG2-A nrPDB 50 2e-06 3IO1-A nrPDB 42 8e-04 2QYV-A nrPDB 42 8e-04 3MRU-A nrPDB 41 0.001 3ISZ-A nrPDB 38 0.009 3IFE-A nrPDB 38 0.011 4O23-A nrPDB 36 0.033 3CT9-A nrPDB 35 0.062 6ESL-A nrPDB 35 0.087 4X8I-A nrPDB 34 0.15 2QE0-A nrPDB 34 0.20 4Q7A-A nrPDB 33 0.31 5DS0-A nrPDB 33 0.36 2WZN-A nrPDB 32 0.57 3HUL-A nrPDB 31 1.1 3KL9-A nrPDB 31 1.1 1Y0Y-A nrPDB 31 1.2 1VHO-A nrPDB 30 1.5 7MDH-A nrPDB 30 1.9 1EZ0-A nrPDB 30 2.6 3E6I-A nrPDB 30 2.7 4H2K-A nrPDB 30 3.2 5XOY-A nrPDB 29 3.3 2J63-A nrPDB 29 6.1 2O2X-A nrPDB 28 8.4 >4PXB-A nrPDB Length = 430 Score = 580 bits (1496), Expect = e-166, Method: Composition-based stats. Identities = 426/427 (99%), Positives = 426/427 (99%) Query: 50 FGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGL 109 FGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGL Sbjct: 4 FGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGL 63 Query: 110 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGF 169 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGF Sbjct: 64 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGF 123 Query: 170 KPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGY 229 KPKRSLEIILFTS EPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGY Sbjct: 124 KPKRSLEIILFTSAEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGY 183 Query: 230 AEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGG 289 AEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGG Sbjct: 184 AEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGG 243 Query: 290 HAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLE 349 HAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLE Sbjct: 244 HAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLE 303 Query: 350 IDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAAT 409 IDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAAT Sbjct: 304 IDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAAT 363 Query: 410 ELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLT 469 ELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLT Sbjct: 364 ELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLT 423 Query: 470 LAKLSLD 476 LAKLSLD Sbjct: 424 LAKLSLD 430 >5THW-A nrPDB Length = 434 Score = 574 bits (1480), Expect = e-164, Method: Composition-based stats. Identities = 133/416 (31%), Positives = 205/416 (49%), Gaps = 11/416 (2%) Query: 55 LASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVRED 114 + S+ VD L N + E++ P V R+ TD D + R + AG TV D Sbjct: 21 IDPSIKVDGKRLWNSLMEMAKIGATPKGGVCRLALTDLDKAGRDLIVRWAKEAGCTVTVD 80 Query: 115 AVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRS 174 +GN+F + G + V TGSH D+ P G++DG+ GVLG +E I L G + + Sbjct: 81 TMGNVFMRRAGRVADAAPVVTGSHADSQPTGGRFDGIYGVLGGLEVIRSLNDHGIETEHP 140 Query: 175 LEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKD 234 +E++++T+EE +RF + + S + AG L L VDG+ + E + GYA D Sbjct: 141 IEVVIWTNEEGSRFAPAMVASGVFAGVFTLEYGLSRKDVDGK--TIGEELQRIGYAGD-- 196 Query: 235 DDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAV 294 V A ELHIEQGPILE E IGVVT ++ F G HAG Sbjct: 197 -----VPCGGRPLHAAFELHIEQGPILEAERKTIGVVTDAQGQRWYEITFTGQEAHAGPT 251 Query: 295 LMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRD 354 MP R DA L A+ + V + L+ TVG++++HP + N IP + +D R Sbjct: 252 PMPRRRDALLGASRVVDLVNRIGLDHAPFGC-ATVGMMQVHPNSRNVIPGRVFFTVDFRH 310 Query: 355 IDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLS 414 D+A + +++ IA ++ + +I P A D ++ + EAA Sbjct: 311 PDDAVLAQMDAALRDGVARIAADIGLETALEQIFYYKPVAF-DPACVQAVREAAERFGYP 369 Query: 415 HKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTL 470 H+ ++S A HD+ ++A+++P M+F+PC G SH E ++PE + G VL + Sbjct: 370 HRDIVSGAGHDACYLAQVAPTSMVFVPCVDGISHNEVEDATPEWIEAGANVLLHAM 425 >5I4M-A nrPDB Length = 434 Score = 557 bits (1435), Expect = e-159, Method: Composition-based stats. Identities = 132/416 (31%), Positives = 202/416 (48%), Gaps = 11/416 (2%) Query: 55 LASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVRED 114 L +S+ VD L + + E++ P V R+ TD D +AR + AG TV D Sbjct: 21 LDTSIKVDGRRLWDSLMEVAKIGATPKGGVCRLALTDLDKAARDLIVGWAKAAGCTVTVD 80 Query: 115 AVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRS 174 +GN+F + G + V TGSH D+ P G++DG+ GVLG +E I L G + + Sbjct: 81 TMGNVFMRRAGRVADAAPVVTGSHADSQPTGGRFDGIYGVLGGLEVIRSLNDHGIETEHP 140 Query: 175 LEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKD 234 +E++++T+EE +RF + + S + AG L L VDG+ + E GYA D Sbjct: 141 VEVVIWTNEEGSRFAPAMVASGVFAGVFPLEYGLSRKDVDGK--TIGEELARIGYAGD-- 196 Query: 235 DDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAV 294 A ELHIEQGPILE E IGVVT ++ F G HAG Sbjct: 197 -----APCGGRKLHAAFELHIEQGPILEAECKTIGVVTDAQGQRWYEITFTGQEAHAGPT 251 Query: 295 LMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRD 354 MP R DA L A+ + V + L+ TVG++++HP + N IP + +D R Sbjct: 252 PMPRRRDALLGASRVVDLVNRIGLDHAPYGC-ATVGMMQVHPNSRNVIPGRVFFTVDFRH 310 Query: 355 IDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLS 414 D+A + +++ IA + + +I P A D + + AA S Sbjct: 311 PDDAVLAKMDAALRDGVARIAADIGLDTALEQIFYYAPIAF-DSACVAAVRAAADRFGYS 369 Query: 415 HKMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTL 470 H+ ++S A HD+ ++A+++P M+F+PC G SH E ++P + G VL + Sbjct: 370 HRDIVSGAGHDACYLAQVAPTSMVFVPCIDGISHNEIEDATPAWIEAGANVLLHAM 425 >4WJB-A nrPDB Length = 424 Score = 528 bits (1361), Expect = e-150, Method: Composition-based stats. Identities = 130/419 (31%), Positives = 200/419 (47%), Gaps = 11/419 (2%) Query: 56 ASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDA 115 AS VD L ++ ++ P V R+ TD D +R AG TVR D Sbjct: 14 ASMPRVDGDRLWASLERMAQIGATPKGGVCRLALTDLDRESRDLFVQWAREAGCTVRVDR 73 Query: 116 VGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSL 175 +GN+F + G P+ V TGSH D+ P G+YDG+ GVLG +E + L + + +R + Sbjct: 74 MGNVFARRAGRRPDAAPVMTGSHADSQPTGGRYDGIYGVLGGLEVVRALNDAAIETERPV 133 Query: 176 EIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDD 235 +++++T+EE +RF + + + + +G L L T DG + E GYA + Sbjct: 134 DVVIWTNEEGSRFAPAMVSAGVFSGVYTLEYGLSRT--DGAGRTIGEELERIGYAGAEP- 190 Query: 236 DLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVL 295 + A ELHIEQG ILE G IGVVTA +V G HAG Sbjct: 191 ------VGGYPVHAAYELHIEQGAILERAGKTIGVVTAGQGQRWYEVTLTGVDAHAGTTP 244 Query: 296 MPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDI 355 M +R DA + AA + VE D TVG++E P + N++P ++ R Sbjct: 245 MAFRRDALVGAARMISFVEVLGRRYAP-DARATVGMIEARPNSRNTVPGGCFFTVEFRHP 303 Query: 356 DEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSH 415 D+A + + ++ +A + + +I P + + I + +AA L LSH Sbjct: 304 DDAVLDELDAALRAELARVADETGLGAQIEQIFTYAPVPFAPR-CIDTVRDAARSLGLSH 362 Query: 416 KMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKLS 474 ++S A HD+ ++AR++P GMIF+PC G SH E +PE G VL + + + Sbjct: 363 MDIVSGAGHDACYVARVAPTGMIFVPCVDGLSHNEAEAITPEWATAGADVLLRAVLQSA 421 >1Z2L-A nrPDB Length = 423 Score = 514 bits (1323), Expect = e-146, Method: Composition-based stats. Identities = 128/411 (31%), Positives = 203/411 (49%), Gaps = 11/411 (2%) Query: 66 LQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDG 125 ++ + LSSF P+ +TR+LY+ + + ++ K MA +GL R D VGN++G+ +G Sbjct: 11 IEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNG 70 Query: 126 LEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEP 185 E V +GSHID + G DG G L A AI+ LK P R++E++ EE Sbjct: 71 TEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEG 130 Query: 186 TRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKG 245 +RF GS+ + G + + D + SF++A ++ G+ ++ + Sbjct: 131 SRFPYVFWGSKNIFGLANPDDV--RNICDAKGNSFVDAMKACGFTLP-----NAPLTPRQ 183 Query: 246 SYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLA 305 AF+ELHIEQG +LE G IGVV AI V G HAG M YR D A Sbjct: 184 DIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYA 243 Query: 306 AAELA-LAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVI 364 + + +VEK + + V T G +E P +N +P K+ ID R D A Sbjct: 244 FSRICHQSVEKAKRMGDPL--VLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFT 301 Query: 365 KKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKMMISRAYH 424 ++++ I + + + ++++P ++ +L + + E L++++M S A H Sbjct: 302 QQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL-VATLTELCEREKLNYRVMHSGAGH 360 Query: 425 DSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKLSL 475 D+ A P MIFIP G SH P E ++ D+A GVK L+L L +L+ Sbjct: 361 DAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAW 411 >5TP4-A nrPDB Length = 431 Score = 508 bits (1308), Expect = e-144, Method: Composition-based stats. Identities = 128/408 (31%), Positives = 202/408 (49%), Gaps = 12/408 (2%) Query: 59 LSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGN 118 L +D L + +++ P V R+ TD D R AG+TV DAVGN Sbjct: 13 LEIDGARLWRSLADMARIGATPRGGVRRLALTDDDRRGRDLFAQWCRDAGMTVSVDAVGN 72 Query: 119 IFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEII 178 +F + DG + V GSH+D P G++DGV GVL +E + L +G + LEI+ Sbjct: 73 LFARRDGADAQAAPVLIGSHLDTQPEGGRFDGVYGVLAGLEVVRTLNDAGIVTDKPLEIV 132 Query: 179 LFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLS 238 +T+EE RF + LGS + G+ L +AL D + ++ A + G Sbjct: 133 SWTNEEGARFAPAMLGSAVFTGALPLDDALARQ--DAEGITLGAALDACG--------CR 182 Query: 239 SVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPY 298 G+ A+ E HIEQGP+LE G IG+VT A L V G HAG MPY Sbjct: 183 GTRAPGGAVDAYFEAHIEQGPVLEANGTTIGIVTGGQAIRWLDVRVTGVAAHAGTTPMPY 242 Query: 299 RNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEA 358 R DA A+A++AL +E+ V + + T+G + + N+I +D R D+A Sbjct: 243 RKDAYFASAQMALELERIV-AGHAPRGLATIGQAGIRNASRNTIAGDVTFTVDLRHHDDA 301 Query: 359 RRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKMM 418 + + + + ++++ +A R V+++ + P D+ ++ +A AA +++ + Sbjct: 302 QVDAMERALRDACARVAAARGVQVAID-TCWRSPATPFDRGCVELVARAAEAFGYTNERI 360 Query: 419 ISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVL 466 +S A HD++ +AR P M+FIPC G SH E + P+D+ G VL Sbjct: 361 VSGAGHDAILLARRVPTAMVFIPCVDGLSHNEAEDALPDDVTRGTNVL 408 >3N5F-A nrPDB Length = 408 Score = 489 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 155/415 (37%), Positives = 229/415 (55%), Gaps = 11/415 (2%) Query: 61 VDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIF 120 + L ++ EL PS VTR+ +T ++ A+ V + M AGL V EDA GN+ Sbjct: 2 IQGERLWQRLMELGEVGKQPSGGVTRLSFTAEERRAKDLVASYMREAGLFVYEDAAGNLI 61 Query: 121 GKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILF 180 G+ +G P+ V GSH+D++ G +DG +GVL +E + + G +E++ F Sbjct: 62 GRKEGTNPDATVVLVGSHLDSVYNGGCFDGPLGVLAGVEVVQTMNEHGVVTHHPIEVVAF 121 Query: 181 TSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSV 240 T EE RF +GSR +AG+ EAL+ D + +S EA + AG D+ L Sbjct: 122 TDEEGARFRFGMIGSRAMAGTLPP-EALECR--DAEGISLAEAMKQAGLDPDR---LPQA 175 Query: 241 FLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRN 300 K G+ A++ELHIEQG +LE+ GL +G+VT IA +K EG HAGA M R Sbjct: 176 ARKPGTVKAYVELHIEQGRVLEETGLPVGIVTGIAGLIWVKFTIEGKAEHAGATPMSLRR 235 Query: 301 DAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARR 360 D AAA++ + +E+ + + TVGTVG L ++PG IN IP + +D RD+ R Sbjct: 236 DPMAAAAQIIIVIEEEARRTGT--TVGTVGQLHVYPGGINVIPERVEFVLDLRDLKAEVR 293 Query: 361 NTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATE-LNLSHKMMI 419 + V K I A TIAK+R V+++ ++ P SD+ +K+ AEAA + L + Sbjct: 294 DQVWKAIAVRAETIAKERNVRVTTERLQEMPPVLCSDE--VKRAAEAACQKLGYPSFWLP 351 Query: 420 SRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKLS 474 S A HDS+ +A I P+GMIF+ G SH P E+S+ ED A G +VL T+ +L+ Sbjct: 352 SGAAHDSVQLAPICPIGMIFVRSQDGVSHSPAEWSTKEDCAAGAEVLYHTVWQLA 406 >2V8D-A nrPDB Length = 474 Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats. Identities = 134/431 (31%), Positives = 209/431 (48%), Gaps = 24/431 (5%) Query: 51 GSINL--ASSLSVDAPGLQNQIDELSS-FSDAPSPS-------VTRVLYTDKDVSARRYV 100 G++NL A+ LS+ + L I E S F + R+ T D + R + Sbjct: 17 GTLNLPAAAPLSIASGRLNQTILETGSQFGGVARWGQESHEFGMRRLAGTALDGAMRDWF 76 Query: 101 KNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEA 160 N G V+ D +GN+F + G P ATGSH+D P +GKYDG++GVL +E Sbjct: 77 TNECESLGCKVKVDKIGNMFAVYPGKNGGKP-TATGSHLDTQPEAGKYDGILGVLAGLEV 135 Query: 161 INVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALK-TTVVDGQNVS 219 + K + + P + ++++ + E RF SC GS + + L EA +V + + S Sbjct: 136 LRTFKDNNYVPNYDVCVVVWFNAEGARFARSCTGSSVWSHDLSLEEAYGLMSVGEDKPES 195 Query: 220 FIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPAS 279 ++ ++ GY D + K+ A ELHIEQGPILEDE IG+VT + A Sbjct: 196 VYDSLKNIGYIGD-----TPASYKENEIDAHFELHIEQGPILEDENKAIGIVTGVQAYNW 250 Query: 280 LKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAI 339 KV G G HAG R DA L ++++ +A + ++ + + T GI++ P ++ Sbjct: 251 QKVTVHGVGAHAGTTPWRLRKDALLMSSKMIVAASEI---AQRHNGLFTCGIIDAKPYSV 307 Query: 340 NSIPSKSHLEIDTRDIDEARRNTVIKKIQESANTIAK-KRKVKLSEFKIVNQDPPALS-D 397 N IP + +D R + T++K+ + + K LS Q PA++ Sbjct: 308 NIIPGEVSFTLDFRHPSDDVLATMLKEAAAEFDRLIKINDGGALSYESETLQVSPAVNFH 367 Query: 398 KLVIKKMAEAA-TELNLSH-KMMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSS 455 ++ I+ ++ +A + + + S A HDS A P MIFIP G SH EYSS Sbjct: 368 EVCIECVSRSAFAQFKKDQVRQIWSGAGHDSCQTAPHVPTSMIFIPSKDGLSHNYYEYSS 427 Query: 456 PEDMANGVKVL 466 PE++ NG KVL Sbjct: 428 PEEIENGFKVL 438 >6C0D-A nrPDB Length = 422 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 119/408 (29%), Positives = 185/408 (45%), Gaps = 14/408 (3%) Query: 59 LSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGN 118 +D L + + L SF P V R+ + D+ ARR++ M AGL D VG Sbjct: 14 PRIDPIRLLDDLKTLRSFGAT-GPGVVRLSLSPVDIDARRWLAGRMTDAGLDAAIDGVGT 72 Query: 119 IFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEII 178 +FG+ +P PA+ GSH D P G DG +GV+ +E L + ++++ Sbjct: 73 VFGR--SRKPG-PALVIGSHSDTQPTGGWLDGALGVIYGLEIARALGECEATREFAVDVA 129 Query: 179 LFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLS 238 + EE T F S LGSR G + ++L++ + + + +A AG A + Sbjct: 130 SWIDEEGT-FS-SFLGSRSFVGDA-IDDSLRSAR-NHEGLLLGDALAQAGLA-----NTP 180 Query: 239 SVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPY 298 V L + A+LE HIEQG LE IGVVT I ++ F G HAG M Sbjct: 181 RVTLDRKRQRAYLEPHIEQGGRLEASAKLIGVVTTIVGIREFQLRFIGQRNHAGTTPMAI 240 Query: 299 RNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEA 358 R DAG A ++ DTV TVG ++L PG+ + +P K+ L + RD + Sbjct: 241 RRDAGAALVAFIAHIDDAFGRLADADTVWTVGRIDLDPGSFSVVPGKAVLHLQFRDANPN 300 Query: 359 RRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKM- 417 R + + + + + V+ + P D + + +A+AA L M Sbjct: 301 RLHAMENALVALVDEWNGQHLVRAELIACEGAEEPVTMDAALQQHLAQAADALAPGQWMH 360 Query: 418 MISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKV 465 M S A HD+ +A+ P M+F+P G SH E ++ + + G +V Sbjct: 361 MPSGASHDAQVIAQHIPACMLFVPSIGGVSHDFIEDTAEQHIVLGCEV 408 >3RZA-A nrPDB Length = 396 Score = 62.4 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 68/384 (17%), Positives = 119/384 (30%), Gaps = 71/384 (18%) Query: 61 VDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVG--- 117 ++ L N EL T + + + +K GL V+ED Sbjct: 21 INEQRLLNTFLELVQIDSE----------TGNESTIQPILKEKFIALGLDVKEDEAAKHP 70 Query: 118 -----NIFGKWDGL--EPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFK 170 N+ + E +P + SH+D V+ AI ++K G+ Sbjct: 71 KLGANNLVCTMNSTIEEGEVPKLYLTSHMDT------------VVPAINVKPIVKDDGY- 117 Query: 171 PKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEAL----KTTVVDGQNVSFIEAARS 226 +++ G + LG+ AG + E L + + GQ I Sbjct: 118 --------IYSD------GTTILGADDKAGLAAMLEVLQVIKEQQIPHGQIQFVITVGEE 163 Query: 227 AGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEG 286 +G K+ + A G ++ V + + G Sbjct: 164 SGLIGAKELNSEL-------LDADF------GYAIDASADVGTTVVGAPTQMLISAKIIG 210 Query: 287 NGGHAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKS 346 HA + + A A A+ + L T +G N + + Sbjct: 211 KTAHA-STP----KEGVSAINIAAKAISRMKLGQVDEITTANIGKFHGGSAT-NIVADEV 264 Query: 347 HLEIDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSD-KLVIKKMA 405 LE + R D R T +K + + T A + K + ++D + V+K Sbjct: 265 ILEAEARSHDPERIKTQVKHMTDVFETTASELGGKAEVTVEQSYPGFKINDNEAVVKIAQ 324 Query: 406 EAATELNLSHKMMISRAYHDSLFM 429 E+A L LS +IS D + Sbjct: 325 ESARNLGLSANTIISGGGSDGSII 348 >3GB0-A nrPDB Length = 373 Score = 61.3 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 64/420 (15%), Positives = 126/420 (30%), Gaps = 56/420 (13%) Query: 61 VDAPGLQNQIDELSSFSDAPS--PSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGN 118 ++ L N+ EL + +V + + V GN Sbjct: 3 INQERLVNEFMELVQVDSETKFEAEICKV----LTKKFTDLGVEVFEDDTMAVTGHGAGN 58 Query: 119 IFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEII 178 + + + + SH+D + +K Sbjct: 59 LICTLPATKDGVDTIYFTSHMDTVVPGNG------------IKPSIKDGYIVSD------ 100 Query: 179 LFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLS 238 G + LG+ AG + EA++ IE + G ++ + Sbjct: 101 ----------GTTILGADDKAGLASMFEAIRVLKEKNIPHGTIEFIITVG---EESGLVG 147 Query: 239 SVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPY 298 + L + A G L+ +G +V A A + G HAG Sbjct: 148 AKALDRERITAKY------GYALDSDGKVGEIVVAAPTQAKVNAIIRGKTAHAGVAP--- 198 Query: 299 RNDAGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEA 358 A A A+ K L +T +G E N + + + R + Sbjct: 199 -EKGVSAITIAAKAIAKMPLGRIDSETTANIGRFEGGTQT-NIVCDHVQIFAEARSLINE 256 Query: 359 RRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSD-KLVIKKMAEAATELNLSHKM 417 + + K++E+ T AK+ V +D V++ AA ++ + + Sbjct: 257 KMEAQVAKMKEAFETTAKEMGGHADVEVNVMYPGFKFADGDHVVEVAKRAAEKIGRTPSL 316 Query: 418 MISRAYHDSLFMARI-SPMGMIFIPCYKGYS--HKPEEYSSPEDMANGVKVLSLTLAKLS 474 S D+ +A P + + GY H E E++A +++ + +++ Sbjct: 317 HQSGGGSDANVIAGHGIPTVNLAV----GYEEIHTTNEKIPVEELAKTAELVVAIIEEVA 372 >5GNE-A nrPDB Length = 375 Score = 51.6 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 73/210 (34%), Gaps = 39/210 (18%) Query: 42 YPIHEPGQFGSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVK 101 YPI+ Q S+ +D + L+S+ + R + V A ++ K Sbjct: 94 YPINHEAQVHSL----FEQIDPAKIWQTNQHLTSY-------INRSAKSRTGVEAAQWFK 142 Query: 102 N----LMALAG---LTVREDAVGNIFGKWD-----GLEPNLPAVATGSHIDAIPYS--GK 147 L G + GN F + G + A+ G+HID + + G Sbjct: 143 QQFDTLAQDYGRKDVESYFVKTGNKFIQPSVVTVIGKDKPGEAIVIGAHIDTLDGNMPGA 202 Query: 148 YDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEA 207 D G+ +E V+ S F+ R + I + +EE +GS + + Sbjct: 203 DDDSSGISVELEMARVVFSSNFELNRPIYFIAYAAEE-----RGLIGSG-----YVVQDF 252 Query: 208 LKTTVVDGQNVSFIEAARSAGYAEDKDDDL 237 L+ + V + AGY + D Sbjct: 253 LQKKI----PVKAVMQLDQAGYRANAKDQT 278 >1CG2-A nrPDB Length = 393 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 69/356 (19%), Positives = 115/356 (32%), Gaps = 95/356 (26%) Query: 101 KNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKY---------DGV 151 AGL V ++ VG I G+ + SH+D + G D Sbjct: 59 VTRSKSAGLVVGDNIVGKIKGR------GGKNLLLMSHMDTVYLKGILAKAPFRVEGDKA 112 Query: 152 VGVLGA---------IEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSK 202 G A + + +LK G + ++ ++ T EE F GSR L Sbjct: 113 YGPGIADDKGGNAVILHTLKLLKEYGVRDYGTITVLFNTDEEKGSF-----GSRDL---- 163 Query: 203 ELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPILE 262 E A+ A Y + + Sbjct: 164 -----------------IQEEAKLADYVLSFEPTSAG----------------------- 183 Query: 263 DEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAVEKHVLESES 322 DE L +G + A ++V G HAGA +A + A++L L ++++ Sbjct: 184 DEKLSLGT----SGIAYVQVNITGKASHAGAAP-ELGVNALVEASDLVLRTMNIDDKAKN 238 Query: 323 IDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVIKKIQESANTIAKKRKVKL 382 + T+ N IP+ + L D R AR ++ +K+ + Sbjct: 239 LRFNWTIAKAG---NVSNIIPASATLNADVRY---ARNEDFDAAMKTLEERAQQKKLPEA 292 Query: 383 SEFKIVNQDPPALS-----DKLVIKKMA---EAATELNLSHKMMISRAYHDSLFMA 430 IV + PA + KLV K +A EA L + + + D+ + A Sbjct: 293 DVKVIVTRGRPAFNAGEGGKKLVDKAVAYYKEAGGTLGVEER---TGGGTDAAYAA 345 >3IO1-A nrPDB Length = 445 Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 46/244 (18%), Positives = 79/244 (32%), Gaps = 25/244 (10%) Query: 246 SYFAFLELHIEQGPILEDEGLDIGVVTAI----AAPASLKVEFEGNGGHAGAVLMPYRND 301 F +HI G+ G V A V+F G HAG RN Sbjct: 201 DVDYFTAIHI-------GTGVPAGTVVCGGDNFMATTKFDVQFSGVAAHAGGKPEDGRNA 253 Query: 302 AGLAAAELALAVEKHVLESESIDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRN 361 AA + + + VG+++ G N +PS + L+++TR EA Sbjct: 254 LLAAAQA--ALGLHAIPPHSAGASRVNVGVMQAGTG-RNVVPSSALLKVETRGESEAINQ 310 Query: 362 TVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATEL-----NLSHK 416 V ++ Q A + + +++ + + + E A + + Sbjct: 311 YVFERAQHVVAGAAAMYEARYEL-RMMGAATASAPSPAWVDYLREQAARVPGVQQAVDRI 369 Query: 417 MMISRAYHDSLFMARISPMG-----MIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLA 471 + + +L MAR+ G MIF H + MA V+ L+ Sbjct: 370 AAPAGSEDATLMMARVQARGGLASYMIFGTELSAGHHNEKFDFDESVMAVAVETLARVAL 429 Query: 472 KLSL 475 Sbjct: 430 NFPW 433 >2QYV-A nrPDB Length = 487 Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 28/88 (31%), Gaps = 12/88 (13%) Query: 60 SVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNI 119 S+ L P PS K+ +++ N G D VGN+ Sbjct: 7 SLQPKLLWQ---WFDQICAIPHPSY-------KEEQLAQFIINWAKTKGFFAERDEVGNV 56 Query: 120 FGKWDGLEP--NLPAVATGSHIDAIPYS 145 + N V +H+D +P + Sbjct: 57 LIRKPATVGMENRKPVVLQAHLDMVPQA 84 >3MRU-A nrPDB Length = 490 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 57/372 (15%), Positives = 112/372 (30%), Gaps = 61/372 (16%) Query: 60 SVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNI 119 ++ L D++ S P P + + + +Y+ G VR D GN+ Sbjct: 10 TLSPAPLWQFFDKICSI---PHP-------SKHEEALAQYIVTWATEQGFDVRRDPTGNV 59 Query: 120 FGKWDGLEP--NLPAVATGSHIDAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEI 177 F K N V +HID +P + + P + Sbjct: 60 FIKKPATPGMENKKGVVLQAHIDMVPQKNE--------------DTDHDFTQDPIQPYID 105 Query: 178 ILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQNV----SFIEAARSAGYAEDK 233 + + + T LG+ G L + + + + E A G + Sbjct: 106 GEWVTAKGTT-----LGADNGIGMASCLAVLASKEIKHGPIEVLLTIDEEAGMTGAFGLE 160 Query: 234 DDDLSSVFLKKGSYFAFLELHIE-QGPILEDEGLDIGVVTAIAAPASLKVEFEG-NGGHA 291 L L E+++ G I DI A + ++ +G GGH+ Sbjct: 161 AGWLKGDILLNTDSEQEGEVYMGCAGGIDGAMTFDITRDAIPAGFITRQLTLKGLKGGHS 220 Query: 292 GAVLMPYRNDAGLAAAELAL-AVEKHVLESESIDTVGTVGILELHPGA-INSIPSKSHLE 349 G + R +A ++ L ++E G+ N+IP ++ + Sbjct: 221 GCDIHTGRGNANKLIGRFLAGHAQELDLR-----------LVEFRGGSLRNAIPREAFVT 269 Query: 350 IDTRDIDEARRNTVIK-----------KIQESANTIAKKRKVKLSEFKIVNQDPPALSDK 398 + ++ + + KI+ T ++ F I +Q + Sbjct: 270 VALPAENQDKLAELFNYYTELLKTELGKIETDIVTFNEEVATDAQVFAIADQQRFIAALN 329 Query: 399 LVIKKMAEAATE 410 + + E Sbjct: 330 ACPNGVMRMSDE 341 >3ISZ-A nrPDB Length = 377 Score = 38.2 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 59/403 (14%), Positives = 124/403 (30%), Gaps = 54/403 (13%) Query: 84 VTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIP 143 + R + D ++ + + G + + W + P +A H D +P Sbjct: 13 IRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEPVIAFAGHTDVVP 72 Query: 144 YSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGIS---CLGSRLLAG 200 + P S EII + +G GS LA Sbjct: 73 TGD------------------ENQWSSPPFSAEII-----DGMLYGRGAADMKGS--LAA 107 Query: 201 SKELAEALKTTVVDGQN-VSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFL---ELHIE 256 AE + + ++ + + A+D + + + + E Sbjct: 108 MIVAAEEYVKANPNHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEP--- 164 Query: 257 QGPILEDEGLDIG--VVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAVE 314 ++G V + + +G GH + + AA + Sbjct: 165 ------SSAKNLGDVVKNGRRGSITGNLYIQGIQGHVAYPHLA--ENPIHKAALFLQELT 216 Query: 315 KHVLESES---IDTVGTVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVIKKIQESA 371 + + + T + + G+ N IP++ +++ + R E + +IK+ Sbjct: 217 TYQWDKGNEFFPPTSLQIANIHAGTGSNNVIPAELYIQFNLRYCTE-VTDEIIKQ---KV 272 Query: 372 NTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATE-LNLSHKMMISRAYHDSLFMA 430 + +K +K ++ P ++ + A E + ++ K D F+A Sbjct: 273 AEMLEKHNLKYRIEWNLSGKPFLTKPGKLLDSITSAIEETIGITPKAETGGGTSDGRFIA 332 Query: 431 RISPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKL 473 + + F P HK E S ED+ ++ L L Sbjct: 333 LMGAEVVEFGP-LNSTIHKVNECVSVEDLGKCGEIYHKMLVNL 374 >3IFE-A nrPDB Length = 434 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 78/394 (19%), Positives = 137/394 (34%), Gaps = 40/394 (10%) Query: 90 TDKDVSARRYVKNLMALAGLT-VREDAVGNIFGKWDG-LEPNLPAVATGSHIDAIPY-SG 146 T + + + + GLT V D G + + ++P + +H+D +G Sbjct: 53 TPGQIEFGKLLVEELKEVGLTEVTMDDNGYVMATLPANTDKDVPVIGFLAHLDTATDFTG 112 Query: 147 K---------YDGVVGVLGA-IEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSR 196 K +DG L + + ++ P I+ T G + LG+ Sbjct: 113 KNVKPQIHENFDGNAITLNEELNIVLTPEQFPELPSYKGHTIITTD------GTTLLGAD 166 Query: 197 LLAGSKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIE 256 AG E+ A+ + + Q + D++ ++ A ++ Sbjct: 167 DKAGLTEIMVAMNYLIHNPQ---IKHGKIRVAFTPDEEIGRGPAHFDVEAFGASFAYMMD 223 Query: 257 QGPILEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAVEKH 316 GP+ GL+ A A K+ F G H G RN A +LA+ H Sbjct: 224 GGPL---GGLEYESFNAAGA----KLTFNGTNTHPGTAKNKMRN-----ATKLAMEFNGH 271 Query: 317 V-LESESIDTVGTVGILELHPGAINSIPSKSHLEI-DT-RDIDEARRNTVIKKIQESANT 373 + +E T G G L + SK++ I D R EAR+NT+ +++ Sbjct: 272 LPVEEAPEYTEGYEGFYHLLSLNGDVEQSKAYYIIRDFDRKNFEARKNTIENIVKQMQEK 331 Query: 374 IAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKMMISRAYHDSLFMARI- 432 + V + N + ++ EA LN+ + R D ++ + Sbjct: 332 YGQDAVVLEMNDQYYNMLEKIEPVREIVDIAYEAMKSLNIEPNIHPIRGGTDGSQLSYMG 391 Query: 433 SPMGMIFIPCYKGYSHKPEEYSSPEDMANGVKVL 466 P IF H EY S + M V+V+ Sbjct: 392 LPTPNIFTGGEN--YHGKFEYVSVDVMEKAVQVI 423 >4O23-A nrPDB Length = 384 Score = 36.2 bits (82), Expect = 0.033, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 20/62 (32%) Query: 84 VTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIP 143 ++R T D ++ + + G E G+ W P V H D +P Sbjct: 17 ISRPSVTPDDRDCQKLLAERLHKIGFAAEELHFGDTKNIWLRRGTKAPVVCFAGHTDVVP 76 Query: 144 YS 145 Sbjct: 77 TG 78 Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 35/207 (16%), Positives = 64/207 (30%), Gaps = 9/207 (4%) Query: 270 VVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLAAA--ELALAVEKHVLESESIDTVG 327 + S + +G GH + A A EL V E T Sbjct: 178 IKNGRRGSLSGNLTVKGKQGHIAYPHLAINPVHTFAPALLELTQEVWDEGNEYFPP-TSF 236 Query: 328 TVGILELHPGAINSIPSKSHLEIDTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKI 387 + + GA N IP + +++ + R E+ +++ + I K V+ Sbjct: 237 QISNINGGTGATNVIPGELNVKFNFRFSTEST----EAGLKQRVHAILDKHGVQYDLQWS 292 Query: 388 VNQDPPALSDKLVIKKMAEA-ATELNLSHKMMISRAYHDSLFMARISPMGMIFIPCYKGY 446 + P + A A + ++ + D F+ I+ + P Sbjct: 293 CSGQPFLTQAGKLTDVARAAIAETCGIEAELSTTGGTSDGRFIKAIAQELIELGPS-NAT 351 Query: 447 SHKPEEYSSPEDMANGVKVLSLTLAKL 473 H+ E D+ V LA+L Sbjct: 352 IHQINENVRLNDIPKLSAVYEGILARL 378 >3CT9-A nrPDB Length = 356 Score = 35.1 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 56/321 (17%), Positives = 101/321 (31%), Gaps = 72/321 (22%) Query: 88 LYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAI-PYSG 146 + ++ A +++N + G+ N++ + P + SHID + P +G Sbjct: 25 SISREETQAADFLQNYIEAEGMQTGRKG-NNVWCLSPMFDLKKPTILLNSHIDTVKPVNG 83 Query: 147 KYDGVV------GVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAG 200 G L + + +G L++ F C S+ Sbjct: 84 WRKDPFTPREENGKLYGLGS----NDAGASVVSLLQV----------FLQLCRTSQN--- 126 Query: 201 SKELAEALKTTVVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPI 260 L + VS E S L V FA + E P Sbjct: 127 -YNLIYLASCE----EEVSGKEGIESV------LPGLPPVS------FAIVGEPTEMQPA 169 Query: 261 LEDEGLDIGVVTAIAAPASLKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAV------- 313 + ++GL + L V G GHA R++ A ++ + Sbjct: 170 IAEKGLMV-----------LDVTATGKAGHAA------RDEGDNAIYKVLNDIAWFRDYR 212 Query: 314 -EKHVLESESIDTVGTVGILELHPGAI-NSIPSKSHLEIDTRDIDEARRNTVIKKIQESA 371 EK + TV ++ G N +P K +D R + + +I++ Sbjct: 213 FEKESPLLGPVKMSVTV----INAGTQHNVVPDKCTFVVDIRSNELYSNEDLFAEIRKHI 268 Query: 372 NTIAKKRKVKLSEFKIVNQDP 392 AK R +L+ +I + P Sbjct: 269 ACDAKARSFRLNSSRIDEKHP 289 >6ESL-A nrPDB Length = 393 Score = 34.7 bits (78), Expect = 0.087, Method: Composition-based stats. Identities = 36/193 (18%), Positives = 68/193 (35%), Gaps = 34/193 (17%) Query: 16 ISLLLPSSLAQQQQHESIRTMEDFSGYP---------IHEPGQFGSINLASSLSVDAPGL 66 +S L +LA QQ + + ++ P ++E +N A+ + + + Sbjct: 75 VSHKLTGTLAANQQQSAQKLLQKKLVKPFGVSKLHKDVYEIKHEEEVN-AALKEIVSDNI 133 Query: 67 QNQIDELSSFSDAPSPSVTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWD-- 124 + ++S+ R D V ++K+ + F K Sbjct: 134 WQTLTHMTSY-------YNRSATKDTGVETANWLKSKFEQMAVEYGRTDTSTFFVKTGWY 186 Query: 125 ---------GLEPNLPAVATGSHIDA----IPYSGKYDGVVGVLGAIEAINVLKRSGFKP 171 G + PA+ G+H+D +P +G D G +EA V+ S Sbjct: 187 KQPSLVTVIGKDIKAPAIVIGAHMDTLDGRMPGAG--DDGSGSSSIMEAARVILSSKTTF 244 Query: 172 KRSLEIILFTSEE 184 KR + I + +EE Sbjct: 245 KRPIYFIWYAAEE 257 >4X8I-A nrPDB Length = 346 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 3/46 (6%) Query: 97 RRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAI 142 R V +++ V+ D +GN+ + G P V +H+D I Sbjct: 25 RDLVVDILKDVADEVKIDKLGNVIAHFKGS---APKVMVAAHMDKI 67 >2QE0-A nrPDB Length = 475 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 34/133 (25%), Positives = 48/133 (36%), Gaps = 14/133 (10%) Query: 152 VGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTT 211 +G + + E K + + R+ EII + +EE R G L GS E A K Sbjct: 82 IGAILSKEVAKGYKSAVSEVVRTAEIINYAAEEGLR----MEGEVLEGGSFEAASKKKIA 137 Query: 212 VVDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPI--------LED 263 VV + V + A Y + + L G+ AF QG I + Sbjct: 138 VVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPP--TQGSISGLLLAEAFAE 195 Query: 264 EGLDIGVVTAIAA 276 GL GV I Sbjct: 196 AGLPAGVFNTITG 208 >4Q7A-A nrPDB Length = 370 Score = 32.8 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 25/68 (36%), Gaps = 3/68 (4%) Query: 96 ARRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVL 155 A ++ MA G D GN G E + G HID +P V GVL Sbjct: 35 AVEWLCQQMAALGYQAEPDGAGNAVGTRG--EGPREIMLLG-HIDTVPGEVPVQVVDGVL 91 Query: 156 GAIEAINV 163 A++ Sbjct: 92 YGRGAVDA 99 >5DS0-A nrPDB Length = 359 Score = 32.8 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 33/110 (30%), Gaps = 9/110 (8%) Query: 145 SGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKEL 204 +D +G +EAI +K G + ++ EE + G++ A + Sbjct: 176 GKAFDDRIGAFVLMEAIRRMKDQGIEHPNTVYGSATVQEE-----VGLRGAQTTAHVVDP 230 Query: 205 AEALKTTV---VDGQNVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFL 251 AL V D + EA G + F+ Sbjct: 231 DVALVLEVDIAGDVPGIKPHEALTKMG-KGPGLVTYDRSMIPNQPLKEFV 279 >2WZN-A nrPDB Length = 354 Score = 32.0 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 52/343 (15%), Positives = 97/343 (28%), Gaps = 71/343 (20%) Query: 97 RRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIPYSGKYDGVVGVLG 156 R V +++ V+ D +GN+ + G P + +H+D I GV+ Sbjct: 33 RDIVVDVLKEVADEVKVDKLGNVIAHFKGSSPR---IMVAAHMDKI----------GVM- 78 Query: 157 AIEAINVLKRSGFKPKRSLEIILFTSEEPTRFGISCLGSRLLAGSKELAEALKTTVVDGQ 216 + ++ + L T+V + Sbjct: 79 ---------------------VNHIDKDG------------YLHIVPIGGVLPETLVAQR 105 Query: 217 NVSFIEAARSAGYAEDKDDDLSSVFLKKGSYFAFLELHIEQGPILEDEGLDIGVVTAIAA 276 F E G L KGS + ++ ++ G ++E ++G Sbjct: 106 IRFFTEKGERYGVVGVLPPHLRRGQEDKGSKIDWDQIVVDVGASSKEEAEEMGFRVGTVG 165 Query: 277 PASLKVEFEGNGGHAGAVLMPYRNDAGLAAAELALAVEKHVLESESIDTVG-TVGILELH 335 F H A A E A + H + + +V VG+ Sbjct: 166 --EFAPNFTRLNEHRFATPYLDDRICLYAMIEAARQLGDHEADIYIVGSVQEEVGLRGAR 223 Query: 336 PGAINSIPS-----KSHLEIDTRD-----------IDEARRNTVIKKIQESANTIAKKRK 379 + P D + K++ A+ +AKK + Sbjct: 224 VASYAINPEVGIAMDVTFAKQPHDKGKIVPELGKGPVMDVGPNINPKLRAFADEVAKKYE 283 Query: 380 VKLSEFKIVNQDPPALSDKLVIKKMAE--AATELNLSHKMMIS 420 + L P +D V++ E A L++ + M S Sbjct: 284 IPLQVEP---SPRPTGTDANVMQINKEGVATAVLSIPIRYMHS 323 >3HUL-A nrPDB Length = 298 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 26/86 (30%), Gaps = 4/86 (4%) Query: 129 NLPAVATGSHI----DAIPYSGKYDGVVGVLGAIEAINVLKRSGFKPKRSLEIILFTSEE 184 NL T H+ D P G V+ IE N L + + I Sbjct: 64 NLAPNLTPHHLVMTCDIPPARGLGSSSAAVVAGIELANTLAELNLSKEEKVRIAAEIEGH 123 Query: 185 PTRFGISCLGSRLLAGSKELAEALKT 210 P + LG+ ++ + + Sbjct: 124 PDNVAPAVLGNWVVGAKLDGEDFYVR 149 >3KL9-A nrPDB Length = 355 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 110 TVREDAVGNIFGKWDGLEPNLPAVATGSHIDAI---PYSGKYDGVVGV--LGAI 158 V D +G IFG + P V SH+D + K DG V +G Sbjct: 39 EVVTDGLGGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGW 92 >1Y0Y-A nrPDB Length = 353 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 18/46 (39%), Gaps = 3/46 (6%) Query: 97 RRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAI 142 R V + V+ D +GN+ G P V +H+D I Sbjct: 30 RDVVIEEIKDYVDEVKVDKLGNVIAHKKG---EGPKVMIAAHMDQI 72 >1VHO-A nrPDB Length = 346 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 7/88 (7%) Query: 394 ALSDKLVIKKMAEAATELNLS-HKMMI---SRAYHDSLFMARI-SPMGMIFIPCYKGYSH 448 + D+ +++K+ E A + N+S + + S D + + R +I IP Y H Sbjct: 252 PVVDRNLVQKIIEIAKKHNVSLQEEAVGGRSGTETDFVQLVRNGVRTSLISIPLK--YMH 309 Query: 449 KPEEYSSPEDMANGVKVLSLTLAKLSLD 476 P E P D+ ++LSL +L ++ Sbjct: 310 TPVEMVDPRDVEELARLLSLVAVELEVE 337 >7MDH-A nrPDB Length = 375 Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 22/63 (34%), Gaps = 2/63 (3%) Query: 58 SLSVDAPGLQNQIDELSSFSDAPSP-SVTRVLYTDKDVSA-RRYVKNLMALAGLTVREDA 115 S+ +D + +D P + R D + K L A+A V+ Sbjct: 97 SIGIDPYEVFEDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASKNVKVLV 156 Query: 116 VGN 118 VGN Sbjct: 157 VGN 159 >1EZ0-A nrPDB Length = 510 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 33/81 (40%), Gaps = 7/81 (8%) Query: 351 DTRDIDEARRNTVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATE 410 D R ++ ++R ++++ I + + AL + + ++A A + Sbjct: 45 DFRRLNNSKRASLLRTIASELEARSDDIIARAHLET-------ALPEVRLTGEIARTANQ 97 Query: 411 LNLSHKMMISRAYHDSLFMAR 431 L L ++ S +YH ++ Sbjct: 98 LRLFADVVNSGSYHQAILDTP 118 >3E6I-A nrPDB Length = 476 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 36/96 (37%), Gaps = 8/96 (8%) Query: 362 TVIKKIQESANTIAKKRKVKLSEFKIVNQDPPALSDKLVIKKMAEAATELNLSHKMMISR 421 + +K+ E + + ++ I ++ D + + E + L + Sbjct: 299 EIEEKLHEEIDRVIGPSRIPA----IKDRQEMPYMDAV----VHEIQRFITLVPSNLPHE 350 Query: 422 AYHDSLFMARISPMGMIFIPCYKGYSHKPEEYSSPE 457 A D++F + P G + +P + +E+ PE Sbjct: 351 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 386 >4H2K-A nrPDB Length = 269 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 9/62 (14%), Positives = 20/62 (32%) Query: 84 VTRVLYTDKDVSARRYVKNLMALAGLTVREDAVGNIFGKWDGLEPNLPAVATGSHIDAIP 143 + R + D ++ + + G + + W + P +A H D +P Sbjct: 16 IRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEPVIAFAGHTDVVP 75 Query: 144 YS 145 Sbjct: 76 TG 77 >5XOY-A nrPDB Length = 373 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 425 DSLFMARISPMGMI-FIPCYKGYSHKPEEYSSPEDMANGVKVLSLTLAKLS 474 D +A P+ M+ + P H P E+ + G++VL L L+ Sbjct: 314 DMNVLAPHWPVPMVAYGPGDSTLDHTPYEHVEVAEFLKGIEVLRGALEALA 364 >2J63-A nrPDB Length = 467 Score = 28.5 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 32/88 (36%), Gaps = 11/88 (12%) Query: 180 FTSEEPTRFGISCLGSR------LLAGSKELAEALKTTVVDGQNVSFIEAARSA-GYAED 232 + +E + +GS + AG +AE D ++ + G+A + Sbjct: 328 WATENAAVPSAAAMGSGSSPHGFIWAGDLNVAE----RDYDRYYAGTFKSMQECSGFAPE 383 Query: 233 KDDDLSSVFLKKGSYFAFLELHIEQGPI 260 + + S F +L+ + GP+ Sbjct: 384 ERMSFRETMQRTNSVDIFRQLYPQAGPV 411 >2O2X-A nrPDB Length = 218 Score = 28.1 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Query: 42 YPIHEPGQF----GSINLASSLSVDAPGLQNQIDELSSFSDAPSPSVTRVLYTDKDVSAR 97 +P H P F G+IN+ + D + + L + + A + V+ T++ AR Sbjct: 27 FPPHLPALFLDRDGTINVDTDYPSDPAEIVLRPQMLPAIATANRAGIPVVVVTNQSGIAR 86 Query: 98 RYVKNLMALAGLTVRE 113 Y A A + R Sbjct: 87 GYF-GWSAFAAVNGRV 101 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.131 0.338 Lambda K H 0.267 0.0403 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,201,034 Number of Sequences: 36641 Number of extensions: 620910 Number of successful extensions: 1959 Number of sequences better than 10.0: 43 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1860 Number of HSP's gapped (non-prelim): 69 length of query: 476 length of database: 10,336,785 effective HSP length: 101 effective length of query: 375 effective length of database: 6,636,044 effective search space: 2488516500 effective search space used: 2488516500 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.1 bits)