BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8TEA1 (469 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5WWT-A nrPDB 964 0.0 5ZVG-B nrPDB 172 2e-43 2YXL-A nrPDB 120 1e-27 1IXK-A nrPDB 109 3e-24 3M4X-A nrPDB 107 1e-23 3AJD-A nrPDB 103 1e-22 6ELZ-q nrPDB 103 1e-22 3M6U-A nrPDB 97 1e-20 2FRX-A nrPDB 96 3e-20 1SQG-A nrPDB 88 7e-18 2B9E-A nrPDB 77 2e-14 4FZV-A nrPDB 67 2e-11 1WXW-A nrPDB 51 9e-07 2AS0-A nrPDB 41 0.001 3CCF-A nrPDB 38 0.008 1UWV-A nrPDB 37 0.020 4DMG-A nrPDB 35 0.050 2YXE-A nrPDB 34 0.17 1EIZ-A nrPDB 33 0.19 4KXX-A nrPDB 33 0.24 3D79-A nrPDB 33 0.35 2B3T-A nrPDB 33 0.36 1Q7H-A nrPDB 32 0.72 3LGA-A nrPDB 32 0.86 5YQS-A nrPDB 30 1.5 1JG3-A nrPDB 30 1.8 5OQL-R nrPDB 30 3.1 5JXR-A nrPDB 29 3.4 3UY5-A nrPDB 29 3.7 5JXT-B nrPDB 29 4.9 5O9X-A nrPDB 29 5.7 2J28-9 nrPDB 28 6.4 2CX0-A nrPDB 28 7.6 2IPX-A nrPDB 28 7.7 5WP4-A nrPDB 28 8.3 5WYK-3B nrPDB 28 8.7 >5WWT-A nrPDB Length = 477 Score = 964 bits (2493), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/469 (100%), Positives = 469/469 (100%) Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH Sbjct: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60 Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC Sbjct: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120 Query: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS Sbjct: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180 Query: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD Sbjct: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240 Query: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL Sbjct: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300 Query: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ Sbjct: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360 Query: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ Sbjct: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420 Query: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST Sbjct: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469 >5ZVG-B nrPDB Length = 384 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 132/431 (30%), Positives = 212/431 (49%), Gaps = 71/431 (16%) Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60 + FPK E+ Y K F GK+EA + ++K L P +RVNT Sbjct: 2 LEAFPK-----ELREYYKNLF---------GKEEANK----IMKKLREPVEHYYIRVNTL 43 Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPR--KNIKKQQCEAIVGA 118 S + L+ EL+K+ GL L+ P L + L GP + + + + Sbjct: 44 KISREK----LIGELKKE--GLKP--LRSPYLPEGLYFVREGPNFSDDFEPKLPVVVANK 95 Query: 119 QCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISE 178 +V +GA +YAPG++ A + +K GD + + D KG + +G GI+ Sbjct: 96 YAAESVYQGAMLYAPGVLKADKNIKEGDEVQI-RDPKG-------------LLVGIGIAR 141 Query: 179 LSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLP---RYLFLQNLPSALVSHVLNPQPG 235 + KE+ +G+ + +T P + PS + Y + Q LPS + + VL P+ Sbjct: 142 MDYKEMTEAT---RGLAVEVTLPKFKLPSLSELKAFEKGYFYPQGLPSMVTARVLEPKED 198 Query: 236 EKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGT 295 + I+D+ AAPGGKTTHIA L+ ++GE+IA+DK N++ K+++N LG+ +++ D Sbjct: 199 DVIIDMAAAPGGKTTHIAQLLENKGEIIAIDKSKNRLRKMEENIKRLGVKNVKLVQMDAR 258 Query: 296 KAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLF 355 K P L D+ILLDAPC+ +G RP + ++K + + QR Sbjct: 259 KL-------------PDLGIKADKILLDAPCTALGVRPKLWEERTLKHIEATARYQRAFI 305 Query: 356 TAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSC 415 AA++ L+ GVLVYSTCT++ ENE V + + K ++L+ Q IG G+ Sbjct: 306 WAAIKSLRRGGVLVYSTCTLSYEENEGNVKFMIRK--GMKLEEQSIFIGSPGI------- 356 Query: 416 EQLKQLQRFDP 426 + ++QRF P Sbjct: 357 -GMNKVQRFYP 366 >2YXL-A nrPDB Length = 450 Score = 120 bits (301), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 68/188 (36%), Positives = 110/188 (58%), Gaps = 18/188 (9%) Query: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKI 275 + +Q SA+ S VL+P+PGE ++DL AAPGGKTTH+A LM ++G++ A D +++++ Sbjct: 241 IIVQEEASAVASIVLDPKPGETVVDLAAAPGGKTTHLAELMKNKGKIYAFDVDKMRMKRL 300 Query: 276 KQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSG---MGQR 332 K +G+ ++ D KA ++ GE E D++LLDAPC+ +G+ Sbjct: 301 KDFVKRMGIKIVKPLVKDARKAPEII------GE-----EVADKVLLDAPCTSSGTIGKN 349 Query: 333 PNMACTWSVKE--VASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK 390 P + W ++E + LQR+L +A +L+KP G L+Y+TC+I ENE+ + W L Sbjct: 350 PEL--RWRLREDKINEMSQLQRELLESAARLVKPGGRLLYTTCSIFKEENEKNIRWFLNV 407 Query: 391 FPCLQLQP 398 P +L P Sbjct: 408 HPEFKLVP 415 >1IXK-A nrPDB Length = 315 Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 71/218 (32%), Positives = 113/218 (51%), Gaps = 21/218 (9%) Query: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKI 275 +++Q S L+P+PGE + D+ AAPGGKT+++A LM + G + A D N++ + Sbjct: 100 IYIQEASSMYPPVALDPKPGEIVADMAAAPGGKTSYLAQLMRNDGVIYAFDVDENRLRET 159 Query: 276 KQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG---QR 332 + N LG+ ++ F +L++ FD+ILLDAPC+G G + Sbjct: 160 RLNLSRLGVLNVILFHSSSLHIGELNV-------------EFDKILLDAPCTGSGTIHKN 206 Query: 333 PNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFP 392 P ++ ++ Q LQ +L +++LKP G+LVYSTC++ ENE + WAL F Sbjct: 207 PERKWNRTMDDIKFCQGLQMRLLEKGLEVLKPGGILVYSTCSLEPEENEFVIQWALDNFD 266 Query: 393 C--LQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSA 428 L L+ EP + G LS E++K +R P Sbjct: 267 VELLPLKYGEPALTNPF--GIELS-EEIKNARRLYPDV 301 >3M4X-A nrPDB Length = 456 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 64/183 (34%), Positives = 101/183 (55%), Gaps = 17/183 (9%) Query: 215 YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEK 274 Y + Q + +V +PGEK+LDLCAAPGGK+T +AA M +G ++ ++IF K K Sbjct: 86 YEYSQEPSAMIVGTAAAAKPGEKVLDLCAAPGGKSTQLAAQMKGKG-LLVTNEIFPKRAK 144 Query: 275 I-KQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG--- 330 I +N G+++ T ++V P FDRI++DAPCSG G Sbjct: 145 ILSENIERWGVSNAIV-----TNHAPAELV-------PHFSGFFDRIVVDAPCSGEGMFR 192 Query: 331 QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK 390 + PN W+ + Q Q+++ ++A+++LK +G L+YSTCT ENEE ++W + Sbjct: 193 KDPNAIKEWTEESPLYCQKRQQEILSSAIKMLKNKGQLIYSTCTFAPEENEEIISWLVEN 252 Query: 391 FPC 393 +P Sbjct: 253 YPV 255 >3AJD-A nrPDB Length = 274 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 66/185 (35%), Positives = 104/185 (56%), Gaps = 20/185 (10%) Query: 213 PRYLFLQNLPSALVSH----VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKI 268 P YLF +P ++ S VLNP+ + ILD+CAAPGGKTTH+A LM ++G ++A++ Sbjct: 58 PEYLFGYYMPQSISSMIPPIVLNPREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVE-- 115 Query: 269 FNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPES---FDRILLDAP 325 + K + AL +N + T + DM + + +L ++ FD+ILLDAP Sbjct: 116 ---ISKTRTKALKSNINRMGVL---NTIIINADMRKYKD----YLLKNEIFFDKILLDAP 165 Query: 326 CSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVA 385 CSG + + S +++ Q++L + LLK +G LVYSTC++ + ENEE + Sbjct: 166 CSGNIIK-DKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIK 224 Query: 386 WALTK 390 + L K Sbjct: 225 YILQK 229 >6ELZ-q nrPDB Length = 618 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 87/275 (31%), Positives = 131/275 (47%), Gaps = 51/275 (18%) Query: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260 P+ +P + L + LQ S L L+P E+ILD+ AAPGGKTT+I+A+M + G Sbjct: 315 PIGATPEY---LAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTG 371 Query: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRI 320 V A D ++ + + N LG + +D E P + FDRI Sbjct: 372 CVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAR-------------EFPKVIGGFDRI 418 Query: 321 LLDAPCSG---MGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLL----KPEGVLVYSTC 373 LLDAPCSG +G+ ++ + + K+ LQ++L +A+ + K GV+VYSTC Sbjct: 419 LLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTC 478 Query: 374 TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGM---RGAGLSCEQLKQLQRFDPSAVP 430 ++ + E+E + +AL K P ++L IG E RG ++F P Sbjct: 479 SVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSYRG-----------KKFHP---- 523 Query: 431 LPDTDMDSLREARREDMLRLANKDSIGFFIAKFVK 465 S++ ARR N D GFF+AKF K Sbjct: 524 -------SVKLARRY-YPHTYNVD--GFFVAKFQK 548 >3M6U-A nrPDB Length = 464 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 69/188 (36%), Positives = 95/188 (50%), Gaps = 24/188 (12%) Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIK 276 ++Q + V +L+P+PGE++LDL AAPGGKTTH+AA M +G ++A N+V+ + Sbjct: 84 YIQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLA-----NEVDGKR 138 Query: 277 QNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPES----FDRILLDAPCSGMG-- 330 LL + A + T+ P L E+ F R+LLDAPCSG G Sbjct: 139 VRGLLENVERWGA------------PLAVTQAPPRALAEAFGTYFHRVLLDAPCSGEGMF 186 Query: 331 -QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALT 389 + A W +Q+ L A +LL P GVLVYSTCT ENE VA L Sbjct: 187 RKDREAARHWGPSAPKRMAEVQKALLAQASRLLGPGGVLVYSTCTFAPEENEGVVAHFLK 246 Query: 390 KFPCLQLQ 397 P +L+ Sbjct: 247 AHPEFRLE 254 >2FRX-A nrPDB Length = 479 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 55/160 (34%), Positives = 84/160 (52%), Gaps = 15/160 (9%) Query: 236 EKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGT 295 ++++D+ AAPG KTT I+A M+++G ++A + ++V+ + N G++++ FDG Sbjct: 119 QRVMDVAAAPGSKTTQISARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGR 178 Query: 296 KAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQR 352 +PE FD ILLDAPCSG G + P+ WS + QR Sbjct: 179 VFGAA------------VPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQR 226 Query: 353 KLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFP 392 +L +A L+P G LVYSTCT+ ENE W +P Sbjct: 227 ELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYP 266 >1SQG-A nrPDB Length = 429 Score = 88.2 bits (217), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 25/190 (13%) Query: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260 PV+ P F+ ++ +Q+ + L PQ GE ILDLCAAPGGKTTHI + + Sbjct: 216 PVHALPGFED---GWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVA-PEA 271 Query: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL---PESF 317 +V+A+D ++ ++ N LG+ + V+ +G P + F Sbjct: 272 QVVAVDIDEQRLSRVYDNLKRLGMKAT---------------VKQGDGRYPSQWCGEQQF 316 Query: 318 DRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCT 374 DRILLDAPCS G + P++ +++ LQ ++ A LK G LVY+TC+ Sbjct: 317 DRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCS 376 Query: 375 ITLAENEEQV 384 + EN Q+ Sbjct: 377 VLPEENSLQI 386 >2B9E-A nrPDB Length = 309 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 65/204 (31%), Positives = 98/204 (48%), Gaps = 25/204 (12%) Query: 215 YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEK 274 +L LQ+ S L + +L+P PG ++D CAAPG KT+H+AAL+ +QG++ A D ++ Sbjct: 83 HLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGKIFAFDL---DAKR 139 Query: 275 IKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG---- 330 + A LL + + + D + + +P + ILLD CSG G Sbjct: 140 LASMATLLARAGVSC-----CELAEEDFLAVSPSDPRY--HEVHYILLDPSCSGSGMPSR 192 Query: 331 --QRPNMACTWSVK--EVASYQPLQRKLFTAAVQLLKPE-GVLVYSTCTITLAENEEQVA 385 + P V+ +A +Q QR L A L P LVYSTC++ ENE+ V Sbjct: 193 QLEEPGAGTPSPVRLHALAGFQ--QRALCHA---LTFPSLQRLVYSTCSLCQEENEDVVR 247 Query: 386 WALTKFP-CLQLQPQEPQIGGEGM 408 AL + P +L P P G+ Sbjct: 248 DALQQNPGAFRLAPALPAWPHRGL 271 >4FZV-A nrPDB Length = 359 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 59/188 (31%), Positives = 89/188 (47%), Gaps = 34/188 (18%) Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT---------THIAALMHDQGEVIALDK 267 +L + S L L QPG+ +LDLCAAPGGKT ++AA + L K Sbjct: 131 YLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQK 190 Query: 268 IFNKV--EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325 I + E+I+ N +R +DG K +L EG +++DR+L+D P Sbjct: 191 ILHSYVPEEIRDG------NQVRVTSWDGRKWGEL------EG------DTYDRVLVDVP 232 Query: 326 CS----GMGQRPNMACTWSVKEVASYQP-LQRKLFTAAVQLLKPEGVLVYSTCTITLAEN 380 C+ + + N S K+ P LQ +L A + KP G +VYSTC+++ +N Sbjct: 233 CTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQN 292 Query: 381 EEQVAWAL 388 E V A+ Sbjct: 293 EYVVQGAI 300 >1WXW-A nrPDB Length = 382 Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 22/145 (15%) Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294 GE+ LD+ + GG H+A EV+A+D + + ++NA L GL ++R Sbjct: 210 GERALDVFSYAGGFALHLALGFR---EVVAVDSSAEALRRAEENARLNGLGNVRVL---- 262 Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKL 354 +A D++ E E E FD ++LD P G++ + KEV Sbjct: 263 -EANAFDLLRRLEKE----GERFDLVVLDPPAFAKGKKDVERAYRAYKEVN--------- 308 Query: 355 FTAAVQLLKPEGVLVYSTCTITLAE 379 A++LLK G+L ++C+ + E Sbjct: 309 -LRAIKLLKEGGILATASCSHHMTE 332 >2AS0-A nrPDB Length = 396 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 63/142 (44%), Gaps = 20/142 (14%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 QPG+++LD+ GG H A D EVI +DK +E K+NA L G+ F Sbjct: 216 QPGDRVLDVFTYTGGFAIHAAIAGAD--EVIGIDKSPRAIETAKENAKLNGVEDRMKFIV 273 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 G+ +++ ++ E FD ++LD P A K++ + Sbjct: 274 -GSAFEEMEKLQKK-------GEKFDIVVLDPP----------AFVQHEKDLKAGLRAYF 315 Query: 353 KLFTAAVQLLKPEGVLVYSTCT 374 + A + L+K G+LV +C+ Sbjct: 316 NVNFAGLNLVKDGGILVTCSCS 337 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 15/67 (22%) Query: 112 CEAIVGAQCGNAVLRGAH-VYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKV 170 +V AQ A+ +GA V+ G+V +K GD++ VY+ +G K Sbjct: 2 ARVVVDAQAARAIGKGAMIVFKKGVVRVEGDIKPGDIVEVYT-------RGGK------- 47 Query: 171 FLGNGIS 177 FLG G + Sbjct: 48 FLGKGFA 54 >3CCF-A nrPDB Length = 279 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 3/50 (6%) Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQN 278 +LNPQPGE ILDL G T IA EV+ D +EK +QN Sbjct: 52 LLNPQPGEFILDLGCGTGQLTEKIA---QSGAEVLGTDNAATMIEKARQN 98 >1UWV-A nrPDB Length = 433 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 12/99 (12%) Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA 289 L+ QP +++LDL G T +A V+ ++ + VEK +QNA L GL ++ Sbjct: 282 LDVQPEDRVLDLFCGMGNFTLPLAT---QAASVVGVEGVPALVEKGQQNARLNGLQNVTF 338 Query: 290 FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSG 328 + + +E+ + P+ FD++LLD +G Sbjct: 339 YH---------ENLEEDVTKQPWAKNGFDKVLLDPARAG 368 >4DMG-A nrPDB Length = 393 Score = 35.4 bits (80), Expect = 0.050, Method: Compositional matrix adjust. Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 26/145 (17%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 +PGE++LD+ + GG A +A+DK + + Q AL LGL Sbjct: 213 RPGERVLDVYSYVGGFALRAA---RKGAYALAVDKDLEALGVLDQAALRLGLR------V 263 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 D L + EG F +LLD P + +RP +E+ + + Sbjct: 264 DIRHGEALPTLRGLEG-------PFHHVLLDPPT--LVKRP--------EELPAMKRHLV 306 Query: 353 KLFTAAVQLLKPEGVLVYSTCTITL 377 L A++LL EG L S+C+ L Sbjct: 307 DLVREALRLLAEEGFLWLSSCSYHL 331 >2YXE-A nrPDB Length = 215 Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 5/105 (4%) Query: 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG 283 ++ +L+ +PG K+L++ G A ++ + G V+++++I EK ++ LG Sbjct: 67 GMMCELLDLKPGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRKLG 126 Query: 284 LNSIRAFCFDGTKAVK----LDMVEDTEGEPPFLPESFDRILLDA 324 +++ DGT + D + T P +PE R L D Sbjct: 127 YDNVIVIVGDGTLGYEPLAPYDRIYTTAAGPK-IPEPLIRQLKDG 170 >1EIZ-A nrPDB Length = 180 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 22/34 (64%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266 +PG ++DL AAPGG + ++ + +G +IA D Sbjct: 21 KPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACD 54 >4KXX-A nrPDB Length = 637 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%) Query: 169 KVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSH 228 K F G GI+ + KE + G P K M ++ + +Y + ++ PS +++ Sbjct: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300 Query: 229 VLNPQ-PGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266 + P P K+ D A +A L H +IALD Sbjct: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALD 339 >3D79-A nrPDB Length = 179 Score = 32.7 bits (73), Expect = 0.35, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 28/53 (52%) Query: 105 KNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGK 157 ++++K +V +L GA V APGIV A + +K GD + V + G+ Sbjct: 88 EDLRKWPRRVVVDEGAVPHILNGADVMAPGIVDADEGIKEGDFVFVVEEKYGR 140 >2B3T-A nrPDB Length = 276 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 14/141 (9%) Query: 179 LSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSA--LVSHVLNPQPGE 236 L+R+ + L G+ + P+++SP+ +++PR P LV L P + Sbjct: 59 LTRRRDGEPIAHLTGVREFWSLPLFVSPA--TLIPR-------PDTECLVEQALARLPEQ 109 Query: 237 --KILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294 +ILDL G +A+ D E+IA+D++ + V ++NA L + +I D Sbjct: 110 PCRILDLGTGTGAIALALASERPD-CEIIAVDRMPDAVSLAQRNAQHLAIKNIHILQSDW 168 Query: 295 TKAVKLDMVEDTEGEPPFLPE 315 A+ PP++ E Sbjct: 169 FSALAGQQFAMIVSNPPYIDE 189 >1Q7H-A nrPDB Length = 153 Score = 31.6 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 17/47 (36%), Positives = 25/47 (53%) Query: 124 VLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKV 170 +L G+ ++APGIVS ++ GD+I V S G E D +V Sbjct: 83 ILNGSDLFAPGIVSMDDSIRKGDMIFVKSSKGYFIAVGMAEMDAGEV 129 >3LGA-A nrPDB Length = 253 Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust. Identities = 35/154 (22%), Positives = 62/154 (40%), Gaps = 40/154 (25%) Query: 223 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLL 282 +AL+ PG+ I++ G T +A ++ +G V++ + I+++ L Sbjct: 82 AALIVAYAGISPGDFIVEAGVGSGALTLFLANIVGPEGRVVSYE--------IREDFAKL 133 Query: 283 GLNSIRAFCFDGTKAVKL-DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSV 341 +I+ FD +KL D+ E E E+ D ++LD P Sbjct: 134 AWENIKWAGFDDRVTIKLKDIYEGIE------EENVDHVILDLP---------------- 171 Query: 342 KEVASYQPLQRKLFTAAVQLLKPEGVLV-YSTCT 374 QP ++ A + LKP G V Y+ C+ Sbjct: 172 ------QP--ERVVEHAAKALKPGGFFVAYTPCS 197 >5YQS-A nrPDB Length = 765 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 275 IKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL 313 I Q A LG+N + D + ++ VE+T GE PFL Sbjct: 138 IGQEASALGVNHVMGPVVDLARELRFGRVEETYGEDPFL 176 >1JG3-A nrPDB Length = 235 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 15/101 (14%) Query: 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG 283 A++ + N +PG IL++ G I+ ++ + +V +++I VE K+N G Sbjct: 81 AIMLEIANLKPGMNILEVGTGSGWNAALISEIV--KTDVYTIERIPELVEFAKRNLERAG 138 Query: 284 LNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324 + ++ DG+K G PP P +D I++ A Sbjct: 139 VKNVHVILGDGSK-----------GFPPKAP--YDVIIVTA 166 >5OQL-R nrPDB Length = 313 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266 +PG K+L L AA G +H+A ++ G V A++ Sbjct: 151 KPGSKVLYLGAASGTSVSHVADIVGPTGAVYAVE 184 >5JXR-A nrPDB Length = 723 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query: 243 AAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG-----LNSIRAFC-FDGTK 296 A PG T L+++ G+++ LDK+ +++K L+ L+ + +C F G K Sbjct: 393 AEPGPPYTTDEHLIYNAGKMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYK 452 Query: 297 AVKLD 301 ++D Sbjct: 453 YCRID 457 >3UY5-A nrPDB Length = 428 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Query: 191 LKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQP-GEKILDLC-AAPGGK 248 L G +R+ P F+++ R+ Q +P L L PQ +++L C AAPGG Sbjct: 184 LGGSSVRLVRPTEHRGEFEAIYERWR--QQVPGGL----LRPQVLWDELLAECKAAPGGD 237 Query: 249 TTHIAALMHDQGEVIALDKIFNKVEKIKQ 277 A L D + +D+ K+ ++ + Sbjct: 238 RESFALLHPDGYALYRVDRTDLKLARVSE 266 >5JXT-B nrPDB Length = 349 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query: 243 AAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG-----LNSIRAFC-FDGTK 296 A PG T L+++ G+++ LDK+ +++K L+ L+ + +C F G K Sbjct: 68 AEPGPPYTTDEHLIYNAGKMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYK 127 Query: 297 AVKLD 301 ++D Sbjct: 128 YCRID 132 >5O9X-A nrPDB Length = 549 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 27/112 (24%), Positives = 41/112 (36%), Gaps = 12/112 (10%) Query: 157 KCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSP---SFDSVLP 213 + +G K V NG+ +E+ LPE G+ I++ ++P +F+ Sbjct: 201 RVMRGVKVKGSLTVDCANGVGGPKLRELIKYLPEDTGLDIKIVNDDVINPDSLNFECGAD 260 Query: 214 RYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIAL 265 Q P P ILD CA+ G I D+G V L Sbjct: 261 YVKTKQRAP---------PSSKASILDRCASLDGDADRILYYFLDEGNVFRL 303 >2J28-9 nrPDB Length = 430 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%) Query: 138 ASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMG 195 AS+ + GDV+S+ DI+ K + E +K+ G+G + L ++K MG Sbjct: 290 ASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDG---FDLNDFLEQLRQMKNMG 344 >2CX0-A nrPDB Length = 187 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 123 AVLRGAHVYAPGIVSASQFMKAGDVI-SVYSDIKGKCKKGAKEFDGT 168 A+ +GAH+ PG+V GDV+ ++Y + + G E D + Sbjct: 104 ALAKGAHLMIPGVVGVEGSFTRGDVVAALYHETRTPVMVGVAEVDSS 150 >2IPX-A nrPDB Length = 233 Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Query: 217 FLQNLPSALVSHV--LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266 F L +A++ V ++ +PG K+L L AA G +H++ ++ G V A++ Sbjct: 58 FRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVE 109 >5WP4-A nrPDB Length = 491 Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 7/71 (9%) Query: 226 VSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG-L 284 V +L P G+ +L+L A G T +A GE+IALD I N IK+N + G Sbjct: 45 VLSLLPPYEGKSVLELGAGIGRFTGELA---QKAGELIALDFIDN---VIKKNESINGHY 98 Query: 285 NSIRAFCFDGT 295 +++ C D T Sbjct: 99 KNVKFMCADVT 109 >5WYK-3B nrPDB Length = 327 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 22/33 (66%) Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266 PG+K+L L AA G +H++ ++ +G V A++ Sbjct: 166 PGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVE 198 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5WWT-A nrPDB 722 0.0 5ZVG-B nrPDB 433 e-122 6ELZ-q nrPDB 253 2e-67 1IXK-A nrPDB 249 3e-66 2YXL-A nrPDB 211 7e-55 3AJD-A nrPDB 202 4e-52 3M4X-A nrPDB 202 4e-52 2FRX-A nrPDB 200 1e-51 3M6U-A nrPDB 198 5e-51 1SQG-A nrPDB 196 2e-50 2B9E-A nrPDB 186 2e-47 4FZV-A nrPDB 151 5e-37 1WXW-A nrPDB 118 5e-27 2AS0-A nrPDB 117 9e-27 Sequences not found previously or not previously below threshold: 3C0K-A nrPDB 70 2e-12 4DMG-A nrPDB 61 7e-10 1UWV-A nrPDB 56 3e-08 1O54-A nrPDB 49 3e-06 3TMA-A nrPDB 49 5e-06 3V8V-A nrPDB 48 8e-06 3A27-A nrPDB 48 9e-06 3D79-A nrPDB 46 5e-05 5YAC-A nrPDB 45 6e-05 1Q7H-A nrPDB 45 8e-05 2VS1-A nrPDB 43 3e-04 5OQL-R nrPDB 42 5e-04 2PWY-A nrPDB 42 7e-04 3A26-A nrPDB 40 0.002 3CCF-A nrPDB 40 0.002 1EIZ-A nrPDB 40 0.003 3VSE-A nrPDB 39 0.004 2IPX-A nrPDB 38 0.007 1NT2-A nrPDB 38 0.009 2ZZN-A nrPDB 38 0.009 5WYK-3B nrPDB 38 0.012 3EEY-A nrPDB 38 0.012 6GKZ-A nrPDB 37 0.016 2ESR-A nrPDB 37 0.021 2IH5-A nrPDB 36 0.033 2B25-A nrPDB 36 0.035 2AUS-C nrPDB 36 0.040 4PON-A nrPDB 36 0.047 4DF3-A nrPDB 36 0.053 3CJR-A nrPDB 35 0.057 3TFW-A nrPDB 35 0.060 2CX0-A nrPDB 35 0.073 2OKC-A nrPDB 35 0.091 3UFB-A nrPDB 34 0.13 5KPG-A nrPDB 34 0.13 2FHP-A nrPDB 34 0.16 2YXD-A nrPDB 34 0.17 1KG4-A nrPDB 34 0.18 2NNW-B nrPDB 34 0.19 3BUS-A nrPDB 34 0.20 3HAY-A nrPDB 33 0.23 4BQH-A nrPDB 33 0.24 1I9G-A nrPDB 33 0.26 3LDF-A nrPDB 33 0.27 2IGT-A nrPDB 33 0.29 6ELZ-w nrPDB 32 0.53 3C3Y-A nrPDB 31 1.00 2PBF-A nrPDB 31 1.1 2J28-9 nrPDB 31 1.2 3BKX-A nrPDB 31 1.3 5VM2-A nrPDB 31 1.5 5LLK-A nrPDB 31 1.6 2GNO-A nrPDB 30 1.8 2HZ7-A nrPDB 30 1.9 1ULZ-A nrPDB 30 1.9 1P6U-A nrPDB 30 2.0 5WP5-A nrPDB 30 2.1 2EQA-A nrPDB 30 2.6 2GKS-A nrPDB 29 3.9 3ZV0-C nrPDB 29 4.3 5O9X-A nrPDB 29 6.0 >5WWT-A nrPDB Length = 477 Score = 722 bits (1863), Expect = 0.0, Method: Composition-based stats. Identities = 469/469 (100%), Positives = 469/469 (100%) Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH Sbjct: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60 Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC Sbjct: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120 Query: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS Sbjct: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180 Query: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD Sbjct: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240 Query: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL Sbjct: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300 Query: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ Sbjct: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360 Query: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ Sbjct: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420 Query: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST Sbjct: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469 >5ZVG-B nrPDB Length = 384 Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats. Identities = 141/472 (29%), Positives = 222/472 (47%), Gaps = 95/472 (20%) Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60 + FPK E+ Y K F GK+EA + ++K L P +RVNT Sbjct: 2 LEAFPK-----ELREYYKNLF---------GKEEANK----IMKKLREPVEHYYIRVNTL 43 Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPR--KNIKKQQCEAIVGA 118 S + L+ EL+K+ GL L+ P L + L GP + + + + Sbjct: 44 KISREK----LIGELKKE--GLKP--LRSPYLPEGLYFVREGPNFSDDFEPKLPVVVANK 95 Query: 119 QCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISE 178 +V +GA +YAPG++ A + +K GD + + D KG + +G GI+ Sbjct: 96 YAAESVYQGAMLYAPGVLKADKNIKEGDEVQI-RDPKG-------------LLVGIGIAR 141 Query: 179 LSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLP---RYLFLQNLPSALVSHVLNPQPG 235 + KE+ +G+ + +T P + PS + Y + Q LPS + + VL P+ Sbjct: 142 MDYKEMTEAT---RGLAVEVTLPKFKLPSLSELKAFEKGYFYPQGLPSMVTARVLEPKED 198 Query: 236 EKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGT 295 + I+D+ AAPGGKTTHIA L+ ++GE+IA+DK N++ K+++N LG+ +++ D Sbjct: 199 DVIIDMAAAPGGKTTHIAQLLENKGEIIAIDKSKNRLRKMEENIKRLGVKNVKLVQMDAR 258 Query: 296 KAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLF 355 K P L D+ILLDAPC+ +G RP + ++K + + QR Sbjct: 259 KL-------------PDLGIKADKILLDAPCTALGVRPKLWEERTLKHIEATARYQRAFI 305 Query: 356 TAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSC 415 AA++ L+ GVLVYSTCT++ ENE V + + K ++L+ Q IG G+ Sbjct: 306 WAAIKSLRRGGVLVYSTCTLSYEENEGNVKFMIRK--GMKLEEQSIFIGSPGI------- 356 Query: 416 EQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCK 467 + ++QRF P L + GFFIAK K K Sbjct: 357 -GMNKVQRFYP--------------------HKHL----TQGFFIAKLRKVK 383 >6ELZ-q nrPDB Length = 618 Score = 253 bits (645), Expect = 2e-67, Method: Composition-based stats. Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 45/272 (16%) Query: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260 P+ +P + L + LQ S L L+P E+ILD+ AAPGGKTT+I+A+M + G Sbjct: 315 PIGATPEY---LAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTG 371 Query: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRI 320 V A D ++ + + N LG + +D + P + FDRI Sbjct: 372 CVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREF-------------PKVIGGFDRI 418 Query: 321 LLDAPCSG---MGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLL----KPEGVLVYSTC 373 LLDAPCSG +G+ ++ + + K+ LQ++L +A+ + K GV+VYSTC Sbjct: 419 LLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTC 478 Query: 374 TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPD 433 ++ + E+E + +AL K P ++L IG E + ++F P Sbjct: 479 SVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSY--------RGKKFHP------- 523 Query: 434 TDMDSLREARREDMLRLANKDSIGFFIAKFVK 465 S++ ARR N D GFF+AKF K Sbjct: 524 ----SVKLARRY-YPHTYNVD--GFFVAKFQK 548 >1IXK-A nrPDB Length = 315 Score = 249 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 81/273 (29%), Positives = 127/273 (46%), Gaps = 45/273 (16%) Query: 198 MTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMH 257 +T + S L +++Q S L+P+PGE + D+ AAPGGKT+++A LM Sbjct: 82 LTREPFSITSTPEFLTGLIYIQEASSMYPPVALDPKPGEIVADMAAAPGGKTSYLAQLMR 141 Query: 258 DQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESF 317 + G + A D N++ + + N LG+ ++ F +L++ F Sbjct: 142 NDGVIYAFDVDENRLRETRLNLSRLGVLNVILFHSSSLHIGELNV-------------EF 188 Query: 318 DRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCT 374 D+ILLDAPC+G G + P ++ ++ Q LQ +L +++LKP G+LVYSTC+ Sbjct: 189 DKILLDAPCTGSGTIHKNPERKWNRTMDDIKFCQGLQMRLLEKGLEVLKPGGILVYSTCS 248 Query: 375 ITLAENEEQVAWALTKFPC--LQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLP 432 + ENE + WAL F L L+ EP + G LS E++K +R P Sbjct: 249 LEPEENEFVIQWALDNFDVELLPLKYGEPALTNPF--GIELS-EEIKNARRLYPDVH--- 302 Query: 433 DTDMDSLREARREDMLRLANKDSIGFFIAKFVK 465 ++ GFFIAK K Sbjct: 303 ---------------------ETSGFFIAKIRK 314 >2YXL-A nrPDB Length = 450 Score = 211 bits (536), Expect = 7e-55, Method: Composition-based stats. Identities = 64/188 (34%), Positives = 104/188 (55%), Gaps = 14/188 (7%) Query: 214 RYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVE 273 + +Q SA+ S VL+P+PGE ++DL AAPGGKTTH+A LM ++G++ A D +++ Sbjct: 239 GKIIVQEEASAVASIVLDPKPGETVVDLAAAPGGKTTHLAELMKNKGKIYAFDVDKMRMK 298 Query: 274 KIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGM---G 330 ++K +G+ ++ D KA ++ E D++LLDAPC+ G Sbjct: 299 RLKDFVKRMGIKIVKPLVKDARKAPEII-----------GEEVADKVLLDAPCTSSGTIG 347 Query: 331 QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK 390 + P + ++ LQR+L +A +L+KP G L+Y+TC+I ENE+ + W L Sbjct: 348 KNPELRWRLREDKINEMSQLQRELLESAARLVKPGGRLLYTTCSIFKEENEKNIRWFLNV 407 Query: 391 FPCLQLQP 398 P +L P Sbjct: 408 HPEFKLVP 415 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 15/99 (15%) Query: 5 PKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASV 64 PK L YL ++ + + LG E E F ++ K H + ++RVNT A+V Sbjct: 144 PKNELEELEWKYLAPSWLIERVKGILG-DETEDFFRSVNK--RH--EWISIRVNTLKANV 198 Query: 65 QHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGP 103 + V + EL++ V +++ + +L I GP Sbjct: 199 EEV----IGELEED----GVEVVRSERVPTILKI--KGP 227 >3AJD-A nrPDB Length = 274 Score = 202 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 69/230 (30%), Positives = 112/230 (48%), Gaps = 17/230 (7%) Query: 202 VYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGE 261 + +P + L Y Q++ S + VLNP+ + ILD+CAAPGGKTTH+A LM ++G Sbjct: 54 IGSTPEY---LFGYYMPQSISSMIPPIVLNPREDDFILDMCAAPGGKTTHLAQLMKNKGT 110 Query: 262 VIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRIL 321 ++A++ + + +K N +G+ + D K + FD+IL Sbjct: 111 IVAVEISKTRTKALKSNINRMGVLNTIIINADMRKYKDYLL---------KNEIFFDKIL 161 Query: 322 LDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENE 381 LDAPCSG + + S +++ Q++L + LLK +G LVYSTC++ + ENE Sbjct: 162 LDAPCSGNIIK-DKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENE 220 Query: 382 EQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPL 431 E + + L K ++L I +G + +K R P P Sbjct: 221 EVIKYILQKRNDVEL----IIIKANEFKGINIKEGYIKGTLRVFPPNEPF 266 >3M4X-A nrPDB Length = 456 Score = 202 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 66/217 (30%), Positives = 108/217 (49%), Gaps = 16/217 (7%) Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272 Y + Q + +V +PGEK+LDLCAAPGGK+T +AA M +G ++ + + Sbjct: 84 AGYEYSQEPSAMIVGTAAAAKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRA 143 Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG-- 330 + + +N G+++ T ++V P FDRI++DAPCSG G Sbjct: 144 KILSENIERWGVSNAIV-----TNHAPAELV-------PHFSGFFDRIVVDAPCSGEGMF 191 Query: 331 -QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALT 389 + PN W+ + Q Q+++ ++A+++LK +G L+YSTCT ENEE ++W + Sbjct: 192 RKDPNAIKEWTEESPLYCQKRQQEILSSAIKMLKNKGQLIYSTCTFAPEENEEIISWLVE 251 Query: 390 KFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDP 426 +P + Q G R S L++ R P Sbjct: 252 NYPVTIEEIPLTQSVSSG-RSEWGSVAGLEKTIRIWP 287 >2FRX-A nrPDB Length = 479 Score = 200 bits (507), Expect = 1e-51, Method: Composition-based stats. Identities = 71/277 (25%), Positives = 112/277 (40%), Gaps = 49/277 (17%) Query: 197 RMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVL--NPQPGEKILDLCAAPGGKTTHIAA 254 P+ + L ++Q S L L + ++++D+ AAPG KTT I+A Sbjct: 81 EDALPLGST---AEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQISA 137 Query: 255 LMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLP 314 M+++G ++A + ++V+ + N G++++ FDG +P Sbjct: 138 RMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAA------------VP 185 Query: 315 ESFDRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYS 371 E FD ILLDAPCSG G + P+ WS + QR+L +A L+P G LVYS Sbjct: 186 EMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYS 245 Query: 372 TCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPL 431 TCT+ ENE W +P F P Sbjct: 246 TCTLNQEENEAVCLWLKETYP---------------------------DAVEFLPLGDLF 278 Query: 432 PDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKS 468 P + E ++ D GFF+A+ K ++ Sbjct: 279 PGANKALTEEGFLHVFPQIY--DCEGFFVARLRKTQA 313 >3M6U-A nrPDB Length = 464 Score = 198 bits (503), Expect = 5e-51, Method: Composition-based stats. Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 25/222 (11%) Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272 ++Q + V +L+P+PGE++LDL AAPGGKTTH+AA M +G ++A + +V Sbjct: 80 AGLYYIQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLANEVDGKRV 139 Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPES----FDRILLDAPCSG 328 + +N G + T+ P L E+ F R+LLDAPCSG Sbjct: 140 RGLLENVERWG-----------------APLAVTQAPPRALAEAFGTYFHRVLLDAPCSG 182 Query: 329 MG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVA 385 G + A W +Q+ L A +LL P GVLVYSTCT ENE VA Sbjct: 183 EGMFRKDREAARHWGPSAPKRMAEVQKALLAQASRLLGPGGVLVYSTCTFAPEENEGVVA 242 Query: 386 WALTKFPCLQLQPQEPQ-IGGEGMRGAGLSCEQLKQLQRFDP 426 L P +L+ + G+ G +L + R P Sbjct: 243 HFLKAHPEFRLEDARLHPLFAPGVPEWGEGNPELLKTARLWP 284 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 45/145 (31%), Gaps = 31/145 (21%) Query: 37 RKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNGLSVPILQH-PDLQDV 95 +F LK L+ +RVNT + F +S L+ P Q+ Sbjct: 16 EEFPAFLKALTEGKRTYGLRVNTLKLPPE------------AFQRISPWPLRPIPWCQEG 63 Query: 96 LLIPVI---GPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGD-VISVY 151 P GP G ++ A G++ K G+ V+ + Sbjct: 64 FYYPEEARPGPHPFF-----------YAGLYYIQEPSAQAVGVL---LDPKPGERVLDLA 109 Query: 152 SDIKGKCKKGAKEFDGTKVFLGNGI 176 + GK A G + L N + Sbjct: 110 AAPGGKTTHLAARMGGKGLLLANEV 134 >1SQG-A nrPDB Length = 429 Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats. Identities = 67/225 (29%), Positives = 105/225 (46%), Gaps = 27/225 (12%) Query: 196 IRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAAL 255 + PV+ P F+ ++ +Q+ + L PQ GE ILDLCAAPGGKTTHI + Sbjct: 211 LETPAPVHALPGFED---GWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEV 267 Query: 256 MHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL-- 313 + +V+A+D ++ ++ N LG+ + V+ +G P Sbjct: 268 -APEAQVVAVDIDEQRLSRVYDNLKRLGMKAT---------------VKQGDGRYPSQWC 311 Query: 314 -PESFDRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLV 369 + FDRILLDAPCS G + P++ +++ LQ ++ A LK G LV Sbjct: 312 GEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLV 371 Query: 370 YSTCTITLAENEEQVAWALTKFPCLQLQPQEP--QIGGEGMRGAG 412 Y+TC++ EN Q+ L + +L Q G + + GA Sbjct: 372 YATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAE 416 >2B9E-A nrPDB Length = 309 Score = 186 bits (472), Expect = 2e-47, Method: Composition-based stats. Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 21/204 (10%) Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272 +L LQ+ S L + +L+P PG ++D CAAPG KT+H+AAL+ +QG++ A D Sbjct: 81 AGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGKIFAFDLDA--- 137 Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG-- 330 +++ A LL + + + D + + +P + ILLD CSG G Sbjct: 138 KRLASMATLLARAGVSC-----CELAEEDFLAVSPSDPRY--HEVHYILLDPSCSGSGMP 190 Query: 331 ----QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPE-GVLVYSTCTITLAENEEQVA 385 + P V+ A QR L A L P LVYSTC++ ENE+ V Sbjct: 191 SRQLEEPGAGTPSPVRLHALAGFQQRALCHA---LTFPSLQRLVYSTCSLCQEENEDVVR 247 Query: 386 WALTKFPC-LQLQPQEPQIGGEGM 408 AL + P +L P P G+ Sbjct: 248 DALQQNPGAFRLAPALPAWPHRGL 271 >4FZV-A nrPDB Length = 359 Score = 151 bits (382), Expect = 5e-37, Method: Composition-based stats. Identities = 57/190 (30%), Positives = 88/190 (46%), Gaps = 34/190 (17%) Query: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT---------THIAALMHDQGEVIALD 266 +L + S L L QPG+ +LDLCAAPGGKT ++AA + L Sbjct: 130 YYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQ 189 Query: 267 KIFNKV--EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324 KI + E+I+ N +R +DG K +L+ +++DR+L+D Sbjct: 190 KILHSYVPEEIRDG------NQVRVTSWDGRKWGELE------------GDTYDRVLVDV 231 Query: 325 PCS----GMGQRPNMACTWSVKEVASYQP-LQRKLFTAAVQLLKPEGVLVYSTCTITLAE 379 PC+ + + N S K+ P LQ +L A + KP G +VYSTC+++ + Sbjct: 232 PCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQ 291 Query: 380 NEEQVAWALT 389 NE V A+ Sbjct: 292 NEYVVQGAIE 301 >1WXW-A nrPDB Length = 382 Score = 118 bits (295), Expect = 5e-27, Method: Composition-based stats. Identities = 47/203 (23%), Positives = 84/203 (41%), Gaps = 33/203 (16%) Query: 188 LPELKGMGIRMTEPVYLSPSFDSVLPRYL-FLQN-LPSALVSHVLNPQP---------GE 236 EL+G+ + + + P V + +L + L+ + GE Sbjct: 152 TRELEGLPLYVRPLLGEVPERVQVQEGRVRYLVDLRAGQKTGAYLDQRENRLYMERFRGE 211 Query: 237 KILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTK 296 + LD+ + GG H+A EV+A+D + + ++NA L GL ++R + Sbjct: 212 RALDVFSYAGGFALHLALGFR---EVVAVDSSAEALRRAEENARLNGLGNVRVL-----E 263 Query: 297 AVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356 A D++ E E E FD ++LD P G++ + KEV Sbjct: 264 ANAFDLLRRLEKE----GERFDLVVLDPPAFAKGKKDVERAYRAYKEVN----------L 309 Query: 357 AAVQLLKPEGVLVYSTCTITLAE 379 A++LLK G+L ++C+ + E Sbjct: 310 RAIKLLKEGGILATASCSHHMTE 332 >2AS0-A nrPDB Length = 396 Score = 117 bits (293), Expect = 9e-27, Method: Composition-based stats. Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 20/146 (13%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 QPG+++LD+ GG H A D EVI +DK +E K+NA L G+ F Sbjct: 216 QPGDRVLDVFTYTGGFAIHAAIAGAD--EVIGIDKSPRAIETAKENAKLNGVEDRMKFIV 273 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 G+ +++ ++ E FD ++LD P A K++ + Sbjct: 274 -GSAFEEMEKLQKK-------GEKFDIVVLDPP----------AFVQHEKDLKAGLRAYF 315 Query: 353 KLFTAAVQLLKPEGVLVYSTCTITLA 378 + A + L+K G+LV +C+ + Sbjct: 316 NVNFAGLNLVKDGGILVTCSCSQHVD 341 Score = 36.0 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 114 AIVGAQCGNAVLRGAH-VYAPGIVSASQFMKAGDVISVYS 152 +V AQ A+ +GA V+ G+V +K GD++ VY+ Sbjct: 4 VVVDAQAARAIGKGAMIVFKKGVVRVEGDIKPGDIVEVYT 43 >3C0K-A nrPDB Length = 396 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 59/163 (36%), Gaps = 22/163 (13%) Query: 212 LPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNK 271 Y Q + +++L+ + GG ++ALM +V+++D Sbjct: 201 KTGYYLDQRDSRLATRRYV---ENKRVLNCFSYTGGFA--VSALMGGCSQVVSVDTSQEA 255 Query: 272 VEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQ 331 ++ +QN L + V+ D+ + E FD I++D P + Sbjct: 256 LDIARQNVELN------KLDLSKAEFVRDDVFKLLRT-YRDRGEKFDVIVMDPPKFVENK 308 Query: 332 RPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCT 374 M K++ A+QLL G+L+ +C+ Sbjct: 309 SQLMGACRGYKDINML----------AIQLLNEGGILLTFSCS 341 >4DMG-A nrPDB Length = 393 Score = 61.4 bits (147), Expect = 7e-10, Method: Composition-based stats. Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 26/144 (18%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 +PGE++LD+ + GG A +A+DK + + Q AL LGL Sbjct: 213 RPGERVLDVYSYVGGFALRAA---RKGAYALAVDKDLEALGVLDQAALRLGLR------V 263 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 D L + EG F +LLD P +E+ + + Sbjct: 264 DIRHGEALPTLRGLEGP-------FHHVLLDPP----------TLVKRPEELPAMKRHLV 306 Query: 353 KLFTAAVQLLKPEGVLVYSTCTIT 376 L A++LL EG L S+C+ Sbjct: 307 DLVREALRLLAEEGFLWLSSCSYH 330 >1UWV-A nrPDB Length = 433 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 12/96 (12%) Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288 L+ QP +++LDL G T +A V+ ++ + VEK +QNA L GL ++ Sbjct: 281 WLDVQPEDRVLDLFCGMGNFTLPLATQAAS---VVGVEGVPALVEKGQQNARLNGLQNVT 337 Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324 + + +E+ + P+ FD++LLD Sbjct: 338 FYH---------ENLEEDVTKQPWAKNGFDKVLLDP 364 >1O54-A nrPDB Length = 277 Score = 49.5 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 53/317 (16%), Positives = 101/317 (31%), Gaps = 63/317 (19%) Query: 137 SASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGI 196 + +K GD + + + + + ++ LG + E+F P G I Sbjct: 15 KVADTLKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGI----IDLNEVFEKGP---GEII 67 Query: 197 RMTEPVY---LSPSFDS----VLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT 249 R + L PS + R + S+ ++ +L+ + G++I+D G Sbjct: 68 RTSAGKKGYILIPSLIDEIMNMKRRTQIVYPKDSSFIAMMLDVKEGDRIIDTGVGSGAMC 127 Query: 250 THIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGE 309 +A + G+V A +K + + N GL ++ ++ + Sbjct: 128 AVLARAVGSSGKVFAYEKREEFAKLAESNLTKWGL-------------IERVTIKVRDIS 174 Query: 310 PPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLV 369 F + D + LD P W+ + LK G Sbjct: 175 EGFDEKDVDALFLDVP-----------DPWNY-------------IDKCWEALKGGGRFA 210 Query: 370 YSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAV 429 T+ N QV L K L ++ R E+L+ + R V Sbjct: 211 ----TVCPTTN--QVQETLKKLQELPFI--RIEVWESLFRPYKPVPERLRPVDRM----V 258 Query: 430 PLPDTDMDSLREARRED 446 + + + RRE+ Sbjct: 259 AHTAYMIFATKVCRREE 275 >3TMA-A nrPDB Length = 354 Score = 49.1 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 51/150 (34%), Gaps = 24/150 (16%) Query: 223 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLL 282 + + + + +PG ++LD G A+ + V A D ++ ++ AL Sbjct: 192 AQALLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLAREAALAS 251 Query: 283 GLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVK 342 GL+ IR D P F PE DRIL + P G R Sbjct: 252 GLSWIRFLRADARHL------------PRFFPE-VDRILANPP---HGLRLGRK------ 289 Query: 343 EVASYQPLQRKLFTAAVQLLKPEGVLVYST 372 L A+ LL P G + T Sbjct: 290 --EGLFHLYWDFLRGALALLPPGGRVALLT 317 >3V8V-A nrPDB Length = 702 Score = 47.9 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 29/137 (21%), Positives = 50/137 (36%), Gaps = 20/137 (14%) Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294 G+ L+L + G T H A + +D +E ++N L GL Sbjct: 539 GKDFLNLFSYTGSATVH--AGLGGARSTTTVDMSRTYLEWAERNLRLNGLTGR------A 590 Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKL 354 + ++ D + E FD I +D P +R A +A + L+R Sbjct: 591 HRLIQADCLAWL----REANEQFDLIFIDPPTFSNSKRMEDAFDVQRDHLALMKDLKR-- 644 Query: 355 FTAAVQLLKPEGVLVYS 371 LL+ G +++S Sbjct: 645 ------LLRAGGTIMFS 655 >3A27-A nrPDB Length = 272 Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 44/132 (33%), Gaps = 3/132 (2%) Query: 188 LPELKGMGIRMTEPVYLSPS--FDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAP 245 P +K + + TE ++ F + + ++ Q E ++D+ A Sbjct: 71 TPHVKILYGKETETIHKEYGCLFKLDVAKIMWSQGNIEERKRMAFISNENEVVVDMFAGI 130 Query: 246 GGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVED 305 G T +A + V A++K + +N L LN++ D D+ + Sbjct: 131 GYFTIPLAKYSKPK-LVYAIEKNPTAYHYLCENIKLNKLNNVIPILADNRDVELKDVADR 189 Query: 306 TEGEPPFLPESF 317 F Sbjct: 190 VIMGYVHKTHKF 201 >3D79-A nrPDB Length = 179 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 50/118 (42%), Gaps = 18/118 (15%) Query: 83 SVPILQHPDL--QDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQ 140 ++ DL V+ + + ++++K +V +L GA V APGIV A + Sbjct: 64 KPMFIRRKDLIFPLVIALYNLSDEEDLRKWPRRVVVDEGAVPHILNGADVMAPGIVDADE 123 Query: 141 FMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRM 198 +K GD + V + G+ L GI+ +S K + + +G +++ Sbjct: 124 GIKEGDFVFVVEEKYGRP-------------LAIGIALMSGKVMKE---KNRGKAVKV 165 >5YAC-A nrPDB Length = 346 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 232 PQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFC 291 Q GE + D+ A G + +A V A D ++ +++N L +N++ Sbjct: 196 AQEGEVVFDMFAGVGPFSILLA---KKAELVFACDINPWAIKYLEENIKLNKVNNVVPIL 252 Query: 292 FDGTKAV 298 D + Sbjct: 253 GDSREIE 259 >1Q7H-A nrPDB Length = 153 Score = 44.9 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 24/121 (19%) Query: 79 FNGLSVPILQHPDL-QDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVS 137 + G + Q DL V L+ P +NI V +L G+ ++APGIVS Sbjct: 43 YIGGKPMVFQAGDLIPSVYLLNYRNPSRNI------VTVDEGAEPHILNGSDLFAPGIVS 96 Query: 138 ASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIR 197 ++ GD+I V S KG F+ G++E+ E+ + +G R Sbjct: 97 MDDSIRKGDMIFVKSS-KGY-------------FIAVGMAEMDAGEV---MATKRGKAAR 139 Query: 198 M 198 + Sbjct: 140 I 140 >2VS1-A nrPDB Length = 425 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 49/140 (35%), Gaps = 42/140 (30%) Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFD 293 GEKILD+ + G ++A + V D +E ++N + ++ Sbjct: 290 EGEKILDMYSGVGTFGIYLAKRGFN---VKGFDSNEFAIEMARRNVEINNVD-------- 338 Query: 294 GTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRK 353 + ++ D E + FD +++D P +G+ R Sbjct: 339 ----AEFEVASDREVSV----KGFDTVIVDPPRAGLHPRLVKRLNRE------------- 377 Query: 354 LFTAAVQLLKPEGVLVYSTC 373 KP GV+VY +C Sbjct: 378 ---------KP-GVIVYVSC 387 >5OQL-R nrPDB Length = 313 Score = 42.2 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 +PG K+L L AA G +H+A ++ G V A++ + A ++ Sbjct: 151 KPGSKVLYLGAASGTSVSHVADIVGPTGAVYAVEFSHRSGRDLINMATR--RTNVIPIVE 208 Query: 293 DGTKAVKLDMV 303 D K + M+ Sbjct: 209 DARKPMAYRML 219 >2PWY-A nrPDB Length = 258 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIK 276 + ++ + + +L+ PG ++L+ GG T +A + ++G V + + + + + + Sbjct: 81 YPKDASAMV--TLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAE 138 Query: 277 QNAL-LLGLNSIR 288 +N + ++R Sbjct: 139 RNVRAFWQVENVR 151 >3A26-A nrPDB Length = 301 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 35/91 (38%), Gaps = 3/91 (3%) Query: 228 HVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSI 287 +P E ++D+ A G + IA ++ + +VIA++K + + +N L + Sbjct: 142 MAKVAKPDELVVDMFAGIGHLSLPIA--VYGKAKVIAIEKDPYTFKFLVENIHLNKVEDR 199 Query: 288 R-AFCFDGTKAVKLDMVEDTEGEPPFLPESF 317 A+ D ++ + F Sbjct: 200 MSAYNMDNRDFPGENIADRILMGYVVRTHEF 230 >3CCF-A nrPDB Length = 279 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 3/50 (6%) Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQN 278 +LNPQPGE ILDL G T IA EV+ D +EK +QN Sbjct: 52 LLNPQPGEFILDLGCGTGQLTEKIAQSG---AEVLGTDNAATMIEKARQN 98 >1EIZ-A nrPDB Length = 180 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 23/39 (58%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNK 271 +PG ++DL AAPGG + ++ + +G +IA D + Sbjct: 21 KPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMD 59 >3VSE-A nrPDB Length = 398 Score = 39.1 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 44/136 (32%), Gaps = 20/136 (14%) Query: 237 KILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTK 296 +L+L + G + A+ V D ++N GLN+I Sbjct: 217 HVLNLFSYTGAFSVIAASEASSTTSV---DLANRSRSLTEEN---FGLNAIDPKSQYIYV 270 Query: 297 AVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356 D + S+D I++D P + K S Q KL Sbjct: 271 MDTFDFYKYAARH----GHSYDTIVIDPPSFA----------RNKKRTFSVQKDYDKLIN 316 Query: 357 AAVQLLKPEGVLVYST 372 A+ +L EG L+ T Sbjct: 317 GALNILSSEGTLLLCT 332 >2IPX-A nrPDB Length = 233 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 54/172 (31%), Gaps = 38/172 (22%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 +PG K+L L AA G +H++ ++ G V A++ + A +I Sbjct: 76 KPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKK--RTNIIPVIE 133 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 D + L D I D QP Q Sbjct: 134 DARH----------PHKYRMLIAMVDVIFADV----------------------AQPDQT 161 Query: 353 KLFT-AAVQLLKPEGVLVYS---TCTITLAENEEQVAWALTKFPCLQLQPQE 400 ++ A L+ G V S C + A E A + K ++PQE Sbjct: 162 RIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQE 213 >1NT2-A nrPDB Length = 210 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 62/158 (39%), Gaps = 11/158 (6%) Query: 221 LPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNAL 280 L H L + E++L L AA G +H+A ++ D+G + A++ EK+ + Sbjct: 44 AAMILKGHRLKLRGDERVLYLGAASGTTVSHLADIV-DEGIIYAVEYSAKPFEKLLELVR 102 Query: 281 LLGLNSIRAFCFDGTK-AVKLDMVEDTEGEPPFLPESFDRILLDAPC----SGMGQRPNM 335 N+I FD +K +VE + + + +L A G+ M Sbjct: 103 E--RNNIIPLLFDASKPWKYSGIVEKVDLIYQDIAQKNQIEILKANAEFFLKEKGEVVIM 160 Query: 336 ACTWSVKEVASYQPLQRKLF---TAAVQLLKPEGVLVY 370 S+ A + + + + +++K ++ Y Sbjct: 161 VKARSIDSTAEPEEVFKSVLKEMEGDFKIVKHGSLMPY 198 >2ZZN-A nrPDB Length = 336 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 32/87 (36%), Gaps = 4/87 (4%) Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294 + ++D+ A G + + ++ A+D + +E +K+N L L Sbjct: 196 NDVVVDMFAGVGPFSI----ACKNAKKIYAIDINPHAIELLKKNIKLNKLEHKIIPILSD 251 Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRIL 321 + V + P F + D+ L Sbjct: 252 VREVDVKGNRVIMNLPKFAHKFIDKAL 278 >5WYK-3B nrPDB Length = 327 Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFD 293 PG+K+L L AA G +H++ ++ +G V A++ ++ A +I D Sbjct: 166 PGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKK--RPNIIPIIED 223 Query: 294 GTKAVKLDMV 303 K M+ Sbjct: 224 ARHPQKYRML 233 >3EEY-A nrPDB Length = 197 Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 50/158 (31%), Gaps = 24/158 (15%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 + G+ ++D G T +A+L+ + G V D + + L L Sbjct: 21 KEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIK 80 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 DG + D + P F+ L +++ Sbjct: 81 DGHQ------NMDKYIDCPVKAVMFNLGYL---------------PSGDHSISTRPETTI 119 Query: 353 KLFTAAVQLLKPEGVL---VYSTCTITLAENEEQVAWA 387 + + A++LL G++ +Y E E+ + + Sbjct: 120 QALSKAMELLVTGGIITVVIYYGGDTGFEEKEKVLEFL 157 >6GKZ-A nrPDB Length = 351 Score = 37.2 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 15/90 (16%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 Q G+ +LDL G T H+A + V A+ ++ E I++ + L ++ Sbjct: 122 QDGQSVLDLGCGQGALTLHVAQKYKN-CRVTAVTNSVSQKEYIEEESRRRNLLNVEVKLA 180 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILL 322 D T + E++DRIL+ Sbjct: 181 DITTHE--------------MAETYDRILV 196 >2ESR-A nrPDB Length = 177 Score = 36.8 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 32/92 (34%), Gaps = 13/92 (14%) Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFD 293 G ++LDL A GG I A+ + ++K I+ N ++ + Sbjct: 31 NGGRVLDLFAGSGGLA--IEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTL--- 85 Query: 294 GTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325 + + E L FD + LD P Sbjct: 86 --------LKMEAERAIDCLTGRFDLVFLDPP 109 >2IH5-A nrPDB Length = 421 Score = 36.0 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 61/188 (32%), Gaps = 37/188 (19%) Query: 193 GMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHI 252 G+ ++ P +P L R + +VS P+ G ++L+ A G Sbjct: 2 GLPPLLSLPSNSAP---RSLGRVETPPEVVDFMVSLAEAPR-GGRVLEPACAHGPFLRAF 57 Query: 253 AALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPF 312 + ++ + D + + + EP Sbjct: 58 REAHGTAYRFVGVEIDPKAL--------------------DLPPWAEGILADFLLWEP-- 95 Query: 313 LPESFDRILLDAP--CSGMGQRPNMACTWSVKEV--------ASYQPLQRKLFTAAVQLL 362 E+FD IL + P G + + +VK++ L AV+LL Sbjct: 96 -GEAFDLILGNPPYGIVGEASKYPIHVFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLL 154 Query: 363 KPEGVLVY 370 KP GVLV+ Sbjct: 155 KPGGVLVF 162 >2B25-A nrPDB Length = 336 Score = 36.0 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 42/96 (43%), Gaps = 2/96 (2%) Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288 +++ PG+ +L+ + GG + ++ + QG VI+ + + + K+N +S + Sbjct: 100 MMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHW-RDSWK 158 Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPE-SFDRILLD 323 + + +D G + +FD + LD Sbjct: 159 LSHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALD 194 >2AUS-C nrPDB Length = 334 Score = 36.0 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 17/98 (17%) Query: 101 IGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKK 160 I P + + + + AV GA++ PGIV + +K GD++++ + Sbjct: 240 IQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMT-------- 291 Query: 161 GAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRM 198 + G + +S +E+ KG+ + + Sbjct: 292 ------LKDELVALGKAMMSTQEMIE---RSKGIAVDV 320 >4PON-A nrPDB Length = 200 Score = 35.6 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 24/70 (34%) Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA 289 + G+ ++D G T +A L+ + G V A D + V K+ Sbjct: 22 MAAGEGDIVIDATMGNGHDTQFLAELVGENGHVYAFDIQESAVANTKERLGEAYQARTTL 81 Query: 290 FCFDGTKAVK 299 F K K Sbjct: 82 FHKSHDKIAK 91 >4DF3-A nrPDB Length = 233 Score = 35.6 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 34/105 (32%), Gaps = 13/105 (12%) Query: 221 LPSALVSHVLNP-QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNA 279 + L + P + G++IL L A G +H++ ++ +G + ++ + Sbjct: 63 AAALLKGLIELPVKEGDRILYLGIASGTTASHMSDIIGPRGRIYGVEFAPRVMR------ 116 Query: 280 LLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324 + D + + L E D + D Sbjct: 117 ------DLLTVVRDRRNIFPILGDARFPEKYRHLVEGVDGLYADV 155 >3CJR-A nrPDB Length = 254 Score = 35.2 bits (79), Expect = 0.057, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 27/61 (44%), Gaps = 3/61 (4%) Query: 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG 283 AL + + +PG+K+LDL G A G+ + +D + + + NA G Sbjct: 110 ALKALARHLRPGDKVLDLGTGSGVLAI---AAEKLGGKALGVDIDPMVLPQAEANAKRNG 166 Query: 284 L 284 + Sbjct: 167 V 167 >3TFW-A nrPDB Length = 248 Score = 35.2 bits (79), Expect = 0.060, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 10/113 (8%) Query: 212 LPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNK 271 LP + N L + ++ ++IL++ G T +A + G+++ L+ + Sbjct: 42 LPAHDVAANQGQFL-ALLVRLTQAKRILEIGTLGGYSTIWMARELPADGQLLTLEADAHH 100 Query: 272 VEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324 + ++N L G++ R +G L+ + + FD I +DA Sbjct: 101 AQVARENLQLAGVDQ-RVTLREGPALQSLESLGECPA--------FDLIFIDA 144 >2CX0-A nrPDB Length = 187 Score = 34.8 bits (78), Expect = 0.073, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 113 EAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVI-SVYSDIKGKCKKGAKEFDGTKV 170 +V A+ +GAH+ PG+V GDV+ ++Y + + G E D + + Sbjct: 94 VVLVDKGAAIALAKGAHLMIPGVVGVEGSFTRGDVVAALYHETRTPVMVGVAEVDSSAL 152 >2OKC-A nrPDB Length = 445 Score = 34.8 bits (78), Expect = 0.091, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 50/166 (30%), Gaps = 24/166 (14%) Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272 F + +NPQ GE + D GG M Q K Sbjct: 150 AGQYFTPRPLIQAMVDCINPQMGETVCDPACGTGGFLLTAYDYMKGQS------ASKEKR 203 Query: 273 EKIKQNALLLGLNSIRA----------FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILL 322 + ++ A L G+++ GT + + E EP L D IL Sbjct: 204 DFLRDKA-LHGVDNTPLVVTLASMNLYLHGIGTDRSPIVCEDSLEKEPSTL---VDVILA 259 Query: 323 DAPCSGMGQRPNMACTWSVKEV-ASYQPLQRKLFTAAVQLLKPEGV 367 + P G RP + + + + Q + +LK G Sbjct: 260 NPP---FGTRPAGSVDINRPDFYVETKNNQLNFLQHMMLMLKTGGR 302 >3UFB-A nrPDB Length = 530 Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 33/195 (16%), Positives = 64/195 (32%), Gaps = 11/195 (5%) Query: 174 NGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQ 233 NGI S +E+ + + M M + S F + P F+ V++PQ Sbjct: 165 NGIHFNSSEEMHTLSRLYETMLREMRDAAGDSGEFYTPRPVVRFMVE--------VMDPQ 216 Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA-FCF 292 GE +LD GG + Q + + ++ + A L ++ Sbjct: 217 LGESVLDPACGTGGFLVEAFEHLERQCKTVEDREVLQESSIFGGEAKSLPYLLVQMNLLL 276 Query: 293 DGTKAVKLDMVEDTEGEPPFLPES--FDRILLDAPCSGMGQRPNMACTWSVKEVASYQPL 350 G + ++D + + D IL + P G ++ + + A L Sbjct: 277 HGLEYPRIDPENSLRFPLREMGDKDRVDVILTNPPFGGEEEKGILGNFPEDMQTAETAML 336 Query: 351 QRKLFTAAVQLLKPE 365 +L ++ Sbjct: 337 FLQLIMRKLKRPGHG 351 >5KPG-A nrPDB Length = 397 Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 56/166 (33%), Gaps = 5/166 (3%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 + G+ ILDL G T H+A +V + ++ E I L L+++ Sbjct: 167 KDGQSILDLGCGHGSLTLHVAQKYRG-CKVTGITNSVSQKEFIMDQCKKLDLSNVEIILE 225 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352 D TK + + L + + Q + +V +YQ Sbjct: 226 DVTKFETEITYDRIFAVALIEHMKNYELFLKKVSTWIAQDGLLFVEHHCHKVFAYQYEPL 285 Query: 353 KLFTAAVQLLKPEGVLVYSTCTI---TLAENEEQVAWALT-KFPCL 394 + + P G LV S+ +I + W L+ K P L Sbjct: 286 DEDDWYTEYIFPSGTLVMSSSSILLYFQEDVSVVNHWTLSGKHPSL 331 >2FHP-A nrPDB Length = 187 Score = 33.7 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 12/92 (13%) Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294 G LDL + GG + D+ I ++K F ++ IK+N A + Sbjct: 45 GGMALDLYSGSGGLAIEAVSRGMDKS--ICIEKNFAALKVIKENI---------AITKEP 93 Query: 295 TKAVKLDMVEDTEGEPPFLPE-SFDRILLDAP 325 K M + E + + FD +LLD P Sbjct: 94 EKFEVRKMDANRALEQFYEEKLQFDLVLLDPP 125 >2YXD-A nrPDB Length = 183 Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA 289 LN + ++D+ GG T IA V A+D + +E KQN + + Sbjct: 31 LNLNKDDVVVDVGCGSGGMTVEIAKRCK---FVYAIDYLDGAIEVTKQNLAKFNIKN--C 85 Query: 290 FCFDGTKAVKLDMVE 304 G LD +E Sbjct: 86 QIIKGRAEDVLDKLE 100 >1KG4-A nrPDB Length = 225 Score = 33.7 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 54/169 (31%), Gaps = 18/169 (10%) Query: 238 ILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKA 297 + DL AP + H+ + L K +V + + A G Sbjct: 62 VTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRST 121 Query: 298 VKLDMVEDTEGEPPFLPESFDRILLDAPCSGM----GQRPNMACTWSVKEVASYQPLQRK 353 + P L + R+L A C + G++ WS+ E + + Sbjct: 122 AGAILSLSLGKHFPILDGNVARVL--ARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVER 179 Query: 354 LFTAAVQLLKPEGVLVYST---CTITLAEN----EEQVAWALTKFPCLQ 395 A + L ++ + C++ +N +WAL +P + Sbjct: 180 FNQAMMDL---GAMICTRSKPKCSLCPLQNGCIAAANNSWAL--YPGKK 223 >2NNW-B nrPDB Length = 234 Score = 33.7 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 32/92 (34%), Gaps = 12/92 (13%) Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292 +PG+ +L L A G +H++ ++ +G++ ++ + ++ Sbjct: 79 KPGKSVLYLGIASGTTASHVSDIVGWEGKIYGIEFSPRVLREL------------VPIVE 126 Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324 + + + E L D I D Sbjct: 127 ERRNIIPILGDATKPEEYRALVTKVDVIFEDV 158 >3BUS-A nrPDB Length = 273 Score = 33.7 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 47/141 (33%), Gaps = 33/141 (23%) Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288 +L+ + G+++LD+ G +A V + +V + A GL + Sbjct: 56 LLDVRSGDRVLDVGCGIGKPAVRLAT--ARDVRVTGISISRPQVNQANARATAAGLANRV 113 Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQ 348 F + + PF SFD + W+++ + Sbjct: 114 TFSY------------ADAMDLPFEDASFDAV------------------WALESLHHMP 143 Query: 349 PLQRKLFTAAVQLLKPEGVLV 369 R L A ++L+P G + Sbjct: 144 DRGRALREMA-RVLRPGGTVA 163 >3HAY-A nrPDB Length = 346 Score = 33.3 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 36/98 (36%), Gaps = 17/98 (17%) Query: 101 IGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKK 160 I P + + + + AV GA + PGI +K GD++++ + Sbjct: 240 IQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMT-------- 291 Query: 161 GAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRM 198 + G + ++ +E+ KG+ + + Sbjct: 292 ------LKDELVALGKAMMTSQEMLEKT---KGIAVDV 320 >4BQH-A nrPDB Length = 549 Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 28/140 (20%), Positives = 48/140 (34%), Gaps = 9/140 (6%) Query: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300 +CAAPGG AAL + D E + Q+ LG+ ++ D A Sbjct: 231 ICAAPGGNGAVFAALAAPRAT-KDKDGTLQVKESLLQHLRKLGIAYVQIGNIDNLLANVA 289 Query: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPN----MACTWSVKEVASYQPLQRKLFT 356 D V + E ++ P G +R + W V E +++ Sbjct: 290 DPVFIGYA----IEEEAHVVVKTCPKRGPDERVGVFVRASGKWGVVEYTEIGDRAKEIDD 345 Query: 357 AAVQLLKPEGVLVYSTCTIT 376 A +L + + C++ Sbjct: 346 ATGELKFNCANISSNLCSLH 365 >1I9G-A nrPDB Length = 280 Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 55/159 (34%), Gaps = 37/159 (23%) Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272 P+ ++ ++ + H + PG ++L+ A G T + + G+VI+ ++ + Sbjct: 80 PQVIYPKDAAQIV--HEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVISYEQRADHA 137 Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQR 332 E ++N G +V + S DR +LD Sbjct: 138 EHARRNVSGC----------YGQPPDNWRLVVSDLADSELPDGSVDRAVLD--------- 178 Query: 333 PNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVL-VY 370 M W ++ A +LL GVL VY Sbjct: 179 --MLAPW-------------EVLDAVSRLLVAGGVLMVY 202 >3LDF-A nrPDB Length = 385 Score = 32.9 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 46/138 (33%), Gaps = 19/138 (13%) Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294 G+ +L+L + + A + L K + A L + + + D Sbjct: 213 GKTVLNLFSYTAAFSVAAAMGGAMATTSVDLAKRSRALSLAHFEANHLDMANHQLVVMD- 271 Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKL 354 V D ++D I++D P + KEV S KL Sbjct: 272 --------VFDYFKYARRHHLTYDIIIIDPPSFA----------RNKKEVFSVSKDYHKL 313 Query: 355 FTAAVQLLKPEGVLVYST 372 +++L G+++ ST Sbjct: 314 IRQGLEILSENGLIIAST 331 >2IGT-A nrPDB Length = 332 Score = 32.9 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 36/98 (36%), Gaps = 13/98 (13%) Query: 261 EVIALDKIFNKVEKIKQNALLLGLNS--IRAFCFDGTKAVKLDMVEDTEGEPPFLPESFD 318 EV +D + K+N +L GL IR C D K ++ + ++D Sbjct: 177 EVTHVDASKKAIGWAKENQVLAGLEQAPIRWICEDAMKFIQREERR---------GSTYD 227 Query: 319 RILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356 IL D P G G + + + R++ + Sbjct: 228 IILTDPPKFGRGTHGEVW--QLFDHLPLMLDICREILS 263 >6ELZ-w nrPDB Length = 841 Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 73/216 (33%), Gaps = 31/216 (14%) Query: 238 ILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKA 297 ++DLCAAPG + L +I +D + K + ++ F D T Sbjct: 50 VIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMK-----------PMPNVITFQSDITTE 98 Query: 298 VKLDMVEDTEGEPPFLPESFDRILLD-APCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356 + D +L D AP G+G W Q + L Sbjct: 99 DCRSKLRGYMKTW-----KADTVLHDGAPNVGLG--------WVQDAFTQSQLTLQALKL 145 Query: 357 AAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCE 416 A L+ G V I +++ ++ W + +++ +P + C+ Sbjct: 146 AVENLVVN-GTFVT---KIFRSKDYNKLIWVFQQLFE-KVEATKPPASRNVSAEIFVVCK 200 Query: 417 QLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLAN 452 K +R DP + P + L + ++ ++ N Sbjct: 201 GFKAPKRLDPRLLD-PKEVFEELPDGQQNMESKIYN 235 >3C3Y-A nrPDB Length = 237 Score = 31.4 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 34/197 (17%), Positives = 64/197 (32%), Gaps = 36/197 (18%) Query: 215 YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEK 274 Y+ L L+S VL +K +++ G A + D G++ A+D E Sbjct: 51 YMSTSPLAGQLMSFVLKLVNAKKTIEVGVFTGYSLLLTALSIPDDGKITAIDFDREAYEI 110 Query: 275 IKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPN 334 G+ F ++++ E E S+D +DA +PN Sbjct: 111 GLPFIRKAGVEHKINFIESDAMLALDNLLQGQESE-----GSYDFGFVDA------DKPN 159 Query: 335 MACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTC----TITLAENEEQVAWALTK 390 ++L+K G++ Y T+ E+E + Sbjct: 160 YIKYH----------------ERLMKLVKVGGIVAYDNTLWGGTVAQPESE-VPDFMKEN 202 Query: 391 FPCL----QLQPQEPQI 403 + +L +P+I Sbjct: 203 REAVIELNKLLAADPRI 219 >2PBF-A nrPDB Length = 227 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 59/156 (37%), Gaps = 15/156 (9%) Query: 233 QPGEKILDLCAAPGGKTTHIAALM----HDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288 +PG + +D+ + G T +A M + VI L+++ + V +N Sbjct: 79 KPGSRAIDVGSGSGYLTVCMAIKMNVLENKNSYVIGLERVKDLVNFSLENIKRDKPE--- 135 Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQ 348 D K + ++ + E E L FD I + A S + P + + Sbjct: 136 LLKIDNFKIIHKNIYQVNEEEKKELG-LFDAIHVGASAS---ELPEILVDLLAENGKLII 191 Query: 349 PLQRKLFTAAVQLLKPEGVLV----YSTCTITLAEN 380 P++ ++ K G ++ + C ++L +N Sbjct: 192 PIEEDYTQVLYEITKKNGKIIKDRLFDVCFVSLKKN 227 >2J28-9 nrPDB Length = 430 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Query: 138 ASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIR 197 AS+ + GDV+S+ DI+ K + E +K+ G+G E + + GM Sbjct: 290 ASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDFLEQLRQMKNMGGMASL 349 Query: 198 MTEPVYLSPSFDSV 211 M P + Sbjct: 350 M----GKLPGMGQI 359 >3BKX-A nrPDB Length = 275 Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 34/104 (32%), Gaps = 3/104 (2%) Query: 219 QNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQN 278 Q ++ +PGEKIL++ G + +A + G V +D Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTL 87 Query: 279 ALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILL 322 T ++ ++ P + FDR++L Sbjct: 88 GQAWNHLLAGPLGDRLTVHFNTNL---SDDLGPIADQHFDRVVL 128 >5VM2-A nrPDB Length = 347 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 28/75 (37%) Query: 203 YLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEV 262 Y P + L + + + +PG+KI+ L A G T A E+ Sbjct: 137 YKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEI 196 Query: 263 IALDKIFNKVEKIKQ 277 +D + ++ +Q Sbjct: 197 AVVDVLEKRLAMAEQ 211 >5LLK-A nrPDB Length = 266 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 6/109 (5%) Query: 205 SPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIA 264 P SV ++ ++ H +P PGE + CAA T L D ++ Sbjct: 96 IPQTSSVFSIEVYPEDHSELQSVHTASPDPGEVVSSACAADEPVTVLTVILDADLTKMTP 155 Query: 265 LDKI--FNKVEKIKQ----NALLLGLNSIRAFCFDGTKAVKLDMVEDTE 307 +I +++ + N L+ + + R F A + + E Sbjct: 156 KQRIDLLHRMRSFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVE 204 >2GNO-A nrPDB Length = 305 Score = 30.2 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 15 NYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNT-----HLASVQHVKN 69 NY E + K ++ ++ ++ LK L PP + + +NT L +++ Sbjct: 75 NYSPELYTRKYVIVHDCERMTQQAANAFLKALEEPPEYAVIVLNTRRWHYLLPTIKSRVF 134 Query: 70 LLLDELQKQFNGL 82 ++ + K+F L Sbjct: 135 RVVVNVPKEFRDL 147 >2HZ7-A nrPDB Length = 851 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 34/195 (17%), Positives = 66/195 (33%), Gaps = 9/195 (4%) Query: 253 AALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPF 312 A + QG+ ++ +++ NA G + D + LD++ + Sbjct: 150 AEQLIRQGDAYVESVSPEELSRLRGNATTPG---TPSPYRDRSVEENLDLLRRMKAGEFA 206 Query: 313 LPESFDRILLD--APCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVY 370 E R +D AP + + P + + + L+ V Sbjct: 207 DGEHVLRAKIDLTAP-NMKLRDPVLYRIVNKPHFRTSDEWHIYPAYDFEHPLQDAIEGVT 265 Query: 371 -STCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAV 429 S C++ +N W + K +P + + G G+ S +L++L + Sbjct: 266 HSMCSLEFVDNRAIYDWLMEKL-NFDPRPHQYEFGRRGLEYTITSKRKLRELVQ-AGRVS 323 Query: 430 PLPDTDMDSLREARR 444 D M +LR RR Sbjct: 324 GWDDPRMPTLRAQRR 338 >1ULZ-A nrPDB Length = 451 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 39/122 (31%), Gaps = 23/122 (18%) Query: 1 MSIFPKISLRPEVENYLKE---------GFMNKEIVTALGKQEAERKFETLLKHLS--HP 49 + I P + L PE Y G+ N + + QE F + + HP Sbjct: 238 VEIAPSLILTPEKREYYGNIVTKAAKEIGYYNAGTMEFIADQEGNLYFIEMNTRIQVEHP 297 Query: 50 PSFTTVRVNTHL--ASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNI 107 S ++ + + L + + +FNG ++ I P+KN Sbjct: 298 VSEMVTGIDIVKWQIKIAAGEPLTIKQEDVKFNGYAIEC----------RINAEDPKKNF 347 Query: 108 KK 109 Sbjct: 348 AP 349 >1P6U-A nrPDB Length = 129 Score = 30.2 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 45/112 (40%), Gaps = 6/112 (5%) Query: 168 TKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYL------SPSFDSVLPRYLFLQNL 221 +++ LG+ + +L K+I + +GM I P +L P D + N Sbjct: 18 SRLLLGDALQQLGFKQITAAGDGEQGMKIMAQNPHHLVISDFNMPKMDGLGLLQAVRANP 77 Query: 222 PSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVE 273 + + ++ G++ L AA G +A + A++ +F ++ Sbjct: 78 ATKKAAFIILTAQGDRALVQKAAALGANNVLAKPFTIEKMKAAIEAVFGALK 129 >5WP5-A nrPDB Length = 491 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNA 279 ++ +PG+K+LD+ GG ++A V+ +D N + + A Sbjct: 278 MDLKPGQKVLDVGCGIGGGDFYMAENF--DVHVVGIDLSVNMISFALERA 325 >2EQA-A nrPDB Length = 352 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 14/98 (14%) Query: 5 PKISLRP---EVENYLKEGFMNKEIVT-ALGKQEAERKFETLLKHLSHPPSFTTVRVN-- 58 P + LRP +E LK+ F I A GK+EAE +K+ + P+ + V Sbjct: 191 PPVLLRPGPFTIEE-LKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPNTRLLLVENR 249 Query: 59 -------THLASVQHVKNLLLDELQKQFNGLSVPILQH 89 + L+ V L+ EL K+F GL IL Sbjct: 250 NIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGS 287 >2GKS-A nrPDB Length = 546 Score = 29.1 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 14/88 (15%) Query: 5 PKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSH--------------PP 50 P S R +V N ++EG + V A + ER + L K PP Sbjct: 454 PYRSARNQVRNMMEEGKFIEVFVDAPVEVCEERDVKGLYKKAKEGLIKGFTGVDDPYEPP 513 Query: 51 SFTTVRVNTHLASVQHVKNLLLDELQKQ 78 VRV+T + + +L+ L+K+ Sbjct: 514 VAPEVRVDTTKLTPEESALKILEFLKKE 541 >3ZV0-C nrPDB Length = 195 Score = 29.1 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 27/65 (41%) Query: 84 VPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMK 143 +P P +D+ GP + + +V NAV GA + PG++ + ++ Sbjct: 48 IPAGSSPLKRDLKSYISSGPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIE 107 Query: 144 AGDVI 148 D I Sbjct: 108 LYDEI 112 >5O9X-A nrPDB Length = 549 Score = 28.7 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 42/109 (38%), Gaps = 6/109 (5%) Query: 157 KCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYL 216 + +G K V NG+ +E+ LPE G+ I++ ++P + Sbjct: 201 RVMRGVKVKGSLTVDCANGVGGPKLRELIKYLPEDTGLDIKIVNDDVINPDSLNFECGAD 260 Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIAL 265 +++ A S + ILD CA+ G I D+G V L Sbjct: 261 YVKTKQRAPPSSKAS------ILDRCASLDGDADRILYYFLDEGNVFRL 303 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.118 0.302 Lambda K H 0.267 0.0354 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,289,028 Number of Sequences: 36641 Number of extensions: 574359 Number of successful extensions: 1889 Number of sequences better than 10.0: 76 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 1742 Number of HSP's gapped (non-prelim): 122 length of query: 469 length of database: 10,336,785 effective HSP length: 101 effective length of query: 368 effective length of database: 6,636,044 effective search space: 2442064192 effective search space used: 2442064192 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.9 bits)