BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q8TEA1
(469 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
5WWT-A nrPDB 964 0.0
5ZVG-B nrPDB 172 2e-43
2YXL-A nrPDB 120 1e-27
1IXK-A nrPDB 109 3e-24
3M4X-A nrPDB 107 1e-23
3AJD-A nrPDB 103 1e-22
6ELZ-q nrPDB 103 1e-22
3M6U-A nrPDB 97 1e-20
2FRX-A nrPDB 96 3e-20
1SQG-A nrPDB 88 7e-18
2B9E-A nrPDB 77 2e-14
4FZV-A nrPDB 67 2e-11
1WXW-A nrPDB 51 9e-07
2AS0-A nrPDB 41 0.001
3CCF-A nrPDB 38 0.008
1UWV-A nrPDB 37 0.020
4DMG-A nrPDB 35 0.050
2YXE-A nrPDB 34 0.17
1EIZ-A nrPDB 33 0.19
4KXX-A nrPDB 33 0.24
3D79-A nrPDB 33 0.35
2B3T-A nrPDB 33 0.36
1Q7H-A nrPDB 32 0.72
3LGA-A nrPDB 32 0.86
5YQS-A nrPDB 30 1.5
1JG3-A nrPDB 30 1.8
5OQL-R nrPDB 30 3.1
5JXR-A nrPDB 29 3.4
3UY5-A nrPDB 29 3.7
5JXT-B nrPDB 29 4.9
5O9X-A nrPDB 29 5.7
2J28-9 nrPDB 28 6.4
2CX0-A nrPDB 28 7.6
2IPX-A nrPDB 28 7.7
5WP4-A nrPDB 28 8.3
5WYK-3B nrPDB 28 8.7
>5WWT-A nrPDB
Length = 477
Score = 964 bits (2493), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60
MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH
Sbjct: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60
Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120
LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC
Sbjct: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120
Query: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180
GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS
Sbjct: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180
Query: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240
RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD
Sbjct: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240
Query: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300
LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL
Sbjct: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300
Query: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360
DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ
Sbjct: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360
Query: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420
LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ
Sbjct: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420
Query: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469
LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST
Sbjct: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469
>5ZVG-B nrPDB
Length = 384
Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 132/431 (30%), Positives = 212/431 (49%), Gaps = 71/431 (16%)
Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60
+ FPK E+ Y K F GK+EA + ++K L P +RVNT
Sbjct: 2 LEAFPK-----ELREYYKNLF---------GKEEANK----IMKKLREPVEHYYIRVNTL 43
Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPR--KNIKKQQCEAIVGA 118
S + L+ EL+K+ GL L+ P L + L GP + + + +
Sbjct: 44 KISREK----LIGELKKE--GLKP--LRSPYLPEGLYFVREGPNFSDDFEPKLPVVVANK 95
Query: 119 QCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISE 178
+V +GA +YAPG++ A + +K GD + + D KG + +G GI+
Sbjct: 96 YAAESVYQGAMLYAPGVLKADKNIKEGDEVQI-RDPKG-------------LLVGIGIAR 141
Query: 179 LSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLP---RYLFLQNLPSALVSHVLNPQPG 235
+ KE+ +G+ + +T P + PS + Y + Q LPS + + VL P+
Sbjct: 142 MDYKEMTEAT---RGLAVEVTLPKFKLPSLSELKAFEKGYFYPQGLPSMVTARVLEPKED 198
Query: 236 EKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGT 295
+ I+D+ AAPGGKTTHIA L+ ++GE+IA+DK N++ K+++N LG+ +++ D
Sbjct: 199 DVIIDMAAAPGGKTTHIAQLLENKGEIIAIDKSKNRLRKMEENIKRLGVKNVKLVQMDAR 258
Query: 296 KAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLF 355
K P L D+ILLDAPC+ +G RP + ++K + + QR
Sbjct: 259 KL-------------PDLGIKADKILLDAPCTALGVRPKLWEERTLKHIEATARYQRAFI 305
Query: 356 TAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSC 415
AA++ L+ GVLVYSTCT++ ENE V + + K ++L+ Q IG G+
Sbjct: 306 WAAIKSLRRGGVLVYSTCTLSYEENEGNVKFMIRK--GMKLEEQSIFIGSPGI------- 356
Query: 416 EQLKQLQRFDP 426
+ ++QRF P
Sbjct: 357 -GMNKVQRFYP 366
>2YXL-A nrPDB
Length = 450
Score = 120 bits (301), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 68/188 (36%), Positives = 110/188 (58%), Gaps = 18/188 (9%)
Query: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKI 275
+ +Q SA+ S VL+P+PGE ++DL AAPGGKTTH+A LM ++G++ A D +++++
Sbjct: 241 IIVQEEASAVASIVLDPKPGETVVDLAAAPGGKTTHLAELMKNKGKIYAFDVDKMRMKRL 300
Query: 276 KQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSG---MGQR 332
K +G+ ++ D KA ++ GE E D++LLDAPC+ +G+
Sbjct: 301 KDFVKRMGIKIVKPLVKDARKAPEII------GE-----EVADKVLLDAPCTSSGTIGKN 349
Query: 333 PNMACTWSVKE--VASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK 390
P + W ++E + LQR+L +A +L+KP G L+Y+TC+I ENE+ + W L
Sbjct: 350 PEL--RWRLREDKINEMSQLQRELLESAARLVKPGGRLLYTTCSIFKEENEKNIRWFLNV 407
Query: 391 FPCLQLQP 398
P +L P
Sbjct: 408 HPEFKLVP 415
>1IXK-A nrPDB
Length = 315
Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 71/218 (32%), Positives = 113/218 (51%), Gaps = 21/218 (9%)
Query: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKI 275
+++Q S L+P+PGE + D+ AAPGGKT+++A LM + G + A D N++ +
Sbjct: 100 IYIQEASSMYPPVALDPKPGEIVADMAAAPGGKTSYLAQLMRNDGVIYAFDVDENRLRET 159
Query: 276 KQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG---QR 332
+ N LG+ ++ F +L++ FD+ILLDAPC+G G +
Sbjct: 160 RLNLSRLGVLNVILFHSSSLHIGELNV-------------EFDKILLDAPCTGSGTIHKN 206
Query: 333 PNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFP 392
P ++ ++ Q LQ +L +++LKP G+LVYSTC++ ENE + WAL F
Sbjct: 207 PERKWNRTMDDIKFCQGLQMRLLEKGLEVLKPGGILVYSTCSLEPEENEFVIQWALDNFD 266
Query: 393 C--LQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSA 428
L L+ EP + G LS E++K +R P
Sbjct: 267 VELLPLKYGEPALTNPF--GIELS-EEIKNARRLYPDV 301
>3M4X-A nrPDB
Length = 456
Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 64/183 (34%), Positives = 101/183 (55%), Gaps = 17/183 (9%)
Query: 215 YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEK 274
Y + Q + +V +PGEK+LDLCAAPGGK+T +AA M +G ++ ++IF K K
Sbjct: 86 YEYSQEPSAMIVGTAAAAKPGEKVLDLCAAPGGKSTQLAAQMKGKG-LLVTNEIFPKRAK 144
Query: 275 I-KQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG--- 330
I +N G+++ T ++V P FDRI++DAPCSG G
Sbjct: 145 ILSENIERWGVSNAIV-----TNHAPAELV-------PHFSGFFDRIVVDAPCSGEGMFR 192
Query: 331 QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK 390
+ PN W+ + Q Q+++ ++A+++LK +G L+YSTCT ENEE ++W +
Sbjct: 193 KDPNAIKEWTEESPLYCQKRQQEILSSAIKMLKNKGQLIYSTCTFAPEENEEIISWLVEN 252
Query: 391 FPC 393
+P
Sbjct: 253 YPV 255
>3AJD-A nrPDB
Length = 274
Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 66/185 (35%), Positives = 104/185 (56%), Gaps = 20/185 (10%)
Query: 213 PRYLFLQNLPSALVSH----VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKI 268
P YLF +P ++ S VLNP+ + ILD+CAAPGGKTTH+A LM ++G ++A++
Sbjct: 58 PEYLFGYYMPQSISSMIPPIVLNPREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVE-- 115
Query: 269 FNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPES---FDRILLDAP 325
+ K + AL +N + T + DM + + +L ++ FD+ILLDAP
Sbjct: 116 ---ISKTRTKALKSNINRMGVL---NTIIINADMRKYKD----YLLKNEIFFDKILLDAP 165
Query: 326 CSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVA 385
CSG + + S +++ Q++L + LLK +G LVYSTC++ + ENEE +
Sbjct: 166 CSGNIIK-DKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIK 224
Query: 386 WALTK 390
+ L K
Sbjct: 225 YILQK 229
>6ELZ-q nrPDB
Length = 618
Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 87/275 (31%), Positives = 131/275 (47%), Gaps = 51/275 (18%)
Query: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260
P+ +P + L + LQ S L L+P E+ILD+ AAPGGKTT+I+A+M + G
Sbjct: 315 PIGATPEY---LAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTG 371
Query: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRI 320
V A D ++ + + N LG + +D E P + FDRI
Sbjct: 372 CVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAR-------------EFPKVIGGFDRI 418
Query: 321 LLDAPCSG---MGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLL----KPEGVLVYSTC 373
LLDAPCSG +G+ ++ + + K+ LQ++L +A+ + K GV+VYSTC
Sbjct: 419 LLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTC 478
Query: 374 TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGM---RGAGLSCEQLKQLQRFDPSAVP 430
++ + E+E + +AL K P ++L IG E RG ++F P
Sbjct: 479 SVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSYRG-----------KKFHP---- 523
Query: 431 LPDTDMDSLREARREDMLRLANKDSIGFFIAKFVK 465
S++ ARR N D GFF+AKF K
Sbjct: 524 -------SVKLARRY-YPHTYNVD--GFFVAKFQK 548
>3M6U-A nrPDB
Length = 464
Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 69/188 (36%), Positives = 95/188 (50%), Gaps = 24/188 (12%)
Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIK 276
++Q + V +L+P+PGE++LDL AAPGGKTTH+AA M +G ++A N+V+ +
Sbjct: 84 YIQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLA-----NEVDGKR 138
Query: 277 QNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPES----FDRILLDAPCSGMG-- 330
LL + A + T+ P L E+ F R+LLDAPCSG G
Sbjct: 139 VRGLLENVERWGA------------PLAVTQAPPRALAEAFGTYFHRVLLDAPCSGEGMF 186
Query: 331 -QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALT 389
+ A W +Q+ L A +LL P GVLVYSTCT ENE VA L
Sbjct: 187 RKDREAARHWGPSAPKRMAEVQKALLAQASRLLGPGGVLVYSTCTFAPEENEGVVAHFLK 246
Query: 390 KFPCLQLQ 397
P +L+
Sbjct: 247 AHPEFRLE 254
>2FRX-A nrPDB
Length = 479
Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 55/160 (34%), Positives = 84/160 (52%), Gaps = 15/160 (9%)
Query: 236 EKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGT 295
++++D+ AAPG KTT I+A M+++G ++A + ++V+ + N G++++ FDG
Sbjct: 119 QRVMDVAAAPGSKTTQISARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGR 178
Query: 296 KAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQR 352
+PE FD ILLDAPCSG G + P+ WS + QR
Sbjct: 179 VFGAA------------VPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQR 226
Query: 353 KLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFP 392
+L +A L+P G LVYSTCT+ ENE W +P
Sbjct: 227 ELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYP 266
>1SQG-A nrPDB
Length = 429
Score = 88.2 bits (217), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 25/190 (13%)
Query: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260
PV+ P F+ ++ +Q+ + L PQ GE ILDLCAAPGGKTTHI + +
Sbjct: 216 PVHALPGFED---GWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVA-PEA 271
Query: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL---PESF 317
+V+A+D ++ ++ N LG+ + V+ +G P + F
Sbjct: 272 QVVAVDIDEQRLSRVYDNLKRLGMKAT---------------VKQGDGRYPSQWCGEQQF 316
Query: 318 DRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCT 374
DRILLDAPCS G + P++ +++ LQ ++ A LK G LVY+TC+
Sbjct: 317 DRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCS 376
Query: 375 ITLAENEEQV 384
+ EN Q+
Sbjct: 377 VLPEENSLQI 386
>2B9E-A nrPDB
Length = 309
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 65/204 (31%), Positives = 98/204 (48%), Gaps = 25/204 (12%)
Query: 215 YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEK 274
+L LQ+ S L + +L+P PG ++D CAAPG KT+H+AAL+ +QG++ A D ++
Sbjct: 83 HLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGKIFAFDL---DAKR 139
Query: 275 IKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG---- 330
+ A LL + + + D + + +P + ILLD CSG G
Sbjct: 140 LASMATLLARAGVSC-----CELAEEDFLAVSPSDPRY--HEVHYILLDPSCSGSGMPSR 192
Query: 331 --QRPNMACTWSVK--EVASYQPLQRKLFTAAVQLLKPE-GVLVYSTCTITLAENEEQVA 385
+ P V+ +A +Q QR L A L P LVYSTC++ ENE+ V
Sbjct: 193 QLEEPGAGTPSPVRLHALAGFQ--QRALCHA---LTFPSLQRLVYSTCSLCQEENEDVVR 247
Query: 386 WALTKFP-CLQLQPQEPQIGGEGM 408
AL + P +L P P G+
Sbjct: 248 DALQQNPGAFRLAPALPAWPHRGL 271
>4FZV-A nrPDB
Length = 359
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/188 (31%), Positives = 89/188 (47%), Gaps = 34/188 (18%)
Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT---------THIAALMHDQGEVIALDK 267
+L + S L L QPG+ +LDLCAAPGGKT ++AA + L K
Sbjct: 131 YLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQK 190
Query: 268 IFNKV--EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325
I + E+I+ N +R +DG K +L EG +++DR+L+D P
Sbjct: 191 ILHSYVPEEIRDG------NQVRVTSWDGRKWGEL------EG------DTYDRVLVDVP 232
Query: 326 CS----GMGQRPNMACTWSVKEVASYQP-LQRKLFTAAVQLLKPEGVLVYSTCTITLAEN 380
C+ + + N S K+ P LQ +L A + KP G +VYSTC+++ +N
Sbjct: 233 CTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQN 292
Query: 381 EEQVAWAL 388
E V A+
Sbjct: 293 EYVVQGAI 300
>1WXW-A nrPDB
Length = 382
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 22/145 (15%)
Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294
GE+ LD+ + GG H+A EV+A+D + + ++NA L GL ++R
Sbjct: 210 GERALDVFSYAGGFALHLALGFR---EVVAVDSSAEALRRAEENARLNGLGNVRVL---- 262
Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKL 354
+A D++ E E E FD ++LD P G++ + KEV
Sbjct: 263 -EANAFDLLRRLEKE----GERFDLVVLDPPAFAKGKKDVERAYRAYKEVN--------- 308
Query: 355 FTAAVQLLKPEGVLVYSTCTITLAE 379
A++LLK G+L ++C+ + E
Sbjct: 309 -LRAIKLLKEGGILATASCSHHMTE 332
>2AS0-A nrPDB
Length = 396
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/142 (26%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
QPG+++LD+ GG H A D EVI +DK +E K+NA L G+ F
Sbjct: 216 QPGDRVLDVFTYTGGFAIHAAIAGAD--EVIGIDKSPRAIETAKENAKLNGVEDRMKFIV 273
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
G+ +++ ++ E FD ++LD P A K++ +
Sbjct: 274 -GSAFEEMEKLQKK-------GEKFDIVVLDPP----------AFVQHEKDLKAGLRAYF 315
Query: 353 KLFTAAVQLLKPEGVLVYSTCT 374
+ A + L+K G+LV +C+
Sbjct: 316 NVNFAGLNLVKDGGILVTCSCS 337
Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 15/67 (22%)
Query: 112 CEAIVGAQCGNAVLRGAH-VYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKV 170
+V AQ A+ +GA V+ G+V +K GD++ VY+ +G K
Sbjct: 2 ARVVVDAQAARAIGKGAMIVFKKGVVRVEGDIKPGDIVEVYT-------RGGK------- 47
Query: 171 FLGNGIS 177
FLG G +
Sbjct: 48 FLGKGFA 54
>3CCF-A nrPDB
Length = 279
Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQN 278
+LNPQPGE ILDL G T IA EV+ D +EK +QN
Sbjct: 52 LLNPQPGEFILDLGCGTGQLTEKIA---QSGAEVLGTDNAATMIEKARQN 98
>1UWV-A nrPDB
Length = 433
Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 12/99 (12%)
Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA 289
L+ QP +++LDL G T +A V+ ++ + VEK +QNA L GL ++
Sbjct: 282 LDVQPEDRVLDLFCGMGNFTLPLAT---QAASVVGVEGVPALVEKGQQNARLNGLQNVTF 338
Query: 290 FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSG 328
+ + +E+ + P+ FD++LLD +G
Sbjct: 339 YH---------ENLEEDVTKQPWAKNGFDKVLLDPARAG 368
>4DMG-A nrPDB
Length = 393
Score = 35.4 bits (80), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 26/145 (17%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+PGE++LD+ + GG A +A+DK + + Q AL LGL
Sbjct: 213 RPGERVLDVYSYVGGFALRAA---RKGAYALAVDKDLEALGVLDQAALRLGLR------V 263
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
D L + EG F +LLD P + +RP +E+ + +
Sbjct: 264 DIRHGEALPTLRGLEG-------PFHHVLLDPPT--LVKRP--------EELPAMKRHLV 306
Query: 353 KLFTAAVQLLKPEGVLVYSTCTITL 377
L A++LL EG L S+C+ L
Sbjct: 307 DLVREALRLLAEEGFLWLSSCSYHL 331
>2YXE-A nrPDB
Length = 215
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG 283
++ +L+ +PG K+L++ G A ++ + G V+++++I EK ++ LG
Sbjct: 67 GMMCELLDLKPGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRKLG 126
Query: 284 LNSIRAFCFDGTKAVK----LDMVEDTEGEPPFLPESFDRILLDA 324
+++ DGT + D + T P +PE R L D
Sbjct: 127 YDNVIVIVGDGTLGYEPLAPYDRIYTTAAGPK-IPEPLIRQLKDG 170
>1EIZ-A nrPDB
Length = 180
Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 22/34 (64%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266
+PG ++DL AAPGG + ++ + +G +IA D
Sbjct: 21 KPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACD 54
>4KXX-A nrPDB
Length = 637
Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 169 KVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSH 228
K F G GI+ + KE + G P K M ++ + +Y + ++ PS +++
Sbjct: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300
Query: 229 VLNPQ-PGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266
+ P P K+ D A +A L H +IALD
Sbjct: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALD 339
>3D79-A nrPDB
Length = 179
Score = 32.7 bits (73), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 28/53 (52%)
Query: 105 KNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGK 157
++++K +V +L GA V APGIV A + +K GD + V + G+
Sbjct: 88 EDLRKWPRRVVVDEGAVPHILNGADVMAPGIVDADEGIKEGDFVFVVEEKYGR 140
>2B3T-A nrPDB
Length = 276
Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 14/141 (9%)
Query: 179 LSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSA--LVSHVLNPQPGE 236
L+R+ + L G+ + P+++SP+ +++PR P LV L P +
Sbjct: 59 LTRRRDGEPIAHLTGVREFWSLPLFVSPA--TLIPR-------PDTECLVEQALARLPEQ 109
Query: 237 --KILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294
+ILDL G +A+ D E+IA+D++ + V ++NA L + +I D
Sbjct: 110 PCRILDLGTGTGAIALALASERPD-CEIIAVDRMPDAVSLAQRNAQHLAIKNIHILQSDW 168
Query: 295 TKAVKLDMVEDTEGEPPFLPE 315
A+ PP++ E
Sbjct: 169 FSALAGQQFAMIVSNPPYIDE 189
>1Q7H-A nrPDB
Length = 153
Score = 31.6 bits (70), Expect = 0.72, Method: Composition-based stats.
Identities = 17/47 (36%), Positives = 25/47 (53%)
Query: 124 VLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKV 170
+L G+ ++APGIVS ++ GD+I V S G E D +V
Sbjct: 83 ILNGSDLFAPGIVSMDDSIRKGDMIFVKSSKGYFIAVGMAEMDAGEV 129
>3LGA-A nrPDB
Length = 253
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 35/154 (22%), Positives = 62/154 (40%), Gaps = 40/154 (25%)
Query: 223 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLL 282
+AL+ PG+ I++ G T +A ++ +G V++ + I+++ L
Sbjct: 82 AALIVAYAGISPGDFIVEAGVGSGALTLFLANIVGPEGRVVSYE--------IREDFAKL 133
Query: 283 GLNSIRAFCFDGTKAVKL-DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSV 341
+I+ FD +KL D+ E E E+ D ++LD P
Sbjct: 134 AWENIKWAGFDDRVTIKLKDIYEGIE------EENVDHVILDLP---------------- 171
Query: 342 KEVASYQPLQRKLFTAAVQLLKPEGVLV-YSTCT 374
QP ++ A + LKP G V Y+ C+
Sbjct: 172 ------QP--ERVVEHAAKALKPGGFFVAYTPCS 197
>5YQS-A nrPDB
Length = 765
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 275 IKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL 313
I Q A LG+N + D + ++ VE+T GE PFL
Sbjct: 138 IGQEASALGVNHVMGPVVDLARELRFGRVEETYGEDPFL 176
>1JG3-A nrPDB
Length = 235
Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG 283
A++ + N +PG IL++ G I+ ++ + +V +++I VE K+N G
Sbjct: 81 AIMLEIANLKPGMNILEVGTGSGWNAALISEIV--KTDVYTIERIPELVEFAKRNLERAG 138
Query: 284 LNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324
+ ++ DG+K G PP P +D I++ A
Sbjct: 139 VKNVHVILGDGSK-----------GFPPKAP--YDVIIVTA 166
>5OQL-R nrPDB
Length = 313
Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266
+PG K+L L AA G +H+A ++ G V A++
Sbjct: 151 KPGSKVLYLGAASGTSVSHVADIVGPTGAVYAVE 184
>5JXR-A nrPDB
Length = 723
Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 243 AAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG-----LNSIRAFC-FDGTK 296
A PG T L+++ G+++ LDK+ +++K L+ L+ + +C F G K
Sbjct: 393 AEPGPPYTTDEHLIYNAGKMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYK 452
Query: 297 AVKLD 301
++D
Sbjct: 453 YCRID 457
>3UY5-A nrPDB
Length = 428
Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 8/89 (8%)
Query: 191 LKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQP-GEKILDLC-AAPGGK 248
L G +R+ P F+++ R+ Q +P L L PQ +++L C AAPGG
Sbjct: 184 LGGSSVRLVRPTEHRGEFEAIYERWR--QQVPGGL----LRPQVLWDELLAECKAAPGGD 237
Query: 249 TTHIAALMHDQGEVIALDKIFNKVEKIKQ 277
A L D + +D+ K+ ++ +
Sbjct: 238 RESFALLHPDGYALYRVDRTDLKLARVSE 266
>5JXT-B nrPDB
Length = 349
Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 243 AAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG-----LNSIRAFC-FDGTK 296
A PG T L+++ G+++ LDK+ +++K L+ L+ + +C F G K
Sbjct: 68 AEPGPPYTTDEHLIYNAGKMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYK 127
Query: 297 AVKLD 301
++D
Sbjct: 128 YCRID 132
>5O9X-A nrPDB
Length = 549
Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 41/112 (36%), Gaps = 12/112 (10%)
Query: 157 KCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSP---SFDSVLP 213
+ +G K V NG+ +E+ LPE G+ I++ ++P +F+
Sbjct: 201 RVMRGVKVKGSLTVDCANGVGGPKLRELIKYLPEDTGLDIKIVNDDVINPDSLNFECGAD 260
Query: 214 RYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIAL 265
Q P P ILD CA+ G I D+G V L
Sbjct: 261 YVKTKQRAP---------PSSKASILDRCASLDGDADRILYYFLDEGNVFRL 303
>2J28-9 nrPDB
Length = 430
Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 138 ASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMG 195
AS+ + GDV+S+ DI+ K + E +K+ G+G + L ++K MG
Sbjct: 290 ASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDG---FDLNDFLEQLRQMKNMG 344
>2CX0-A nrPDB
Length = 187
Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 123 AVLRGAHVYAPGIVSASQFMKAGDVI-SVYSDIKGKCKKGAKEFDGT 168
A+ +GAH+ PG+V GDV+ ++Y + + G E D +
Sbjct: 104 ALAKGAHLMIPGVVGVEGSFTRGDVVAALYHETRTPVMVGVAEVDSS 150
>2IPX-A nrPDB
Length = 233
Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 217 FLQNLPSALVSHV--LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266
F L +A++ V ++ +PG K+L L AA G +H++ ++ G V A++
Sbjct: 58 FRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVE 109
>5WP4-A nrPDB
Length = 491
Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 226 VSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG-L 284
V +L P G+ +L+L A G T +A GE+IALD I N IK+N + G
Sbjct: 45 VLSLLPPYEGKSVLELGAGIGRFTGELA---QKAGELIALDFIDN---VIKKNESINGHY 98
Query: 285 NSIRAFCFDGT 295
+++ C D T
Sbjct: 99 KNVKFMCADVT 109
>5WYK-3B nrPDB
Length = 327
Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266
PG+K+L L AA G +H++ ++ +G V A++
Sbjct: 166 PGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVE 198
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
5WWT-A nrPDB 722 0.0
5ZVG-B nrPDB 433 e-122
6ELZ-q nrPDB 253 2e-67
1IXK-A nrPDB 249 3e-66
2YXL-A nrPDB 211 7e-55
3AJD-A nrPDB 202 4e-52
3M4X-A nrPDB 202 4e-52
2FRX-A nrPDB 200 1e-51
3M6U-A nrPDB 198 5e-51
1SQG-A nrPDB 196 2e-50
2B9E-A nrPDB 186 2e-47
4FZV-A nrPDB 151 5e-37
1WXW-A nrPDB 118 5e-27
2AS0-A nrPDB 117 9e-27
Sequences not found previously or not previously below threshold:
3C0K-A nrPDB 70 2e-12
4DMG-A nrPDB 61 7e-10
1UWV-A nrPDB 56 3e-08
1O54-A nrPDB 49 3e-06
3TMA-A nrPDB 49 5e-06
3V8V-A nrPDB 48 8e-06
3A27-A nrPDB 48 9e-06
3D79-A nrPDB 46 5e-05
5YAC-A nrPDB 45 6e-05
1Q7H-A nrPDB 45 8e-05
2VS1-A nrPDB 43 3e-04
5OQL-R nrPDB 42 5e-04
2PWY-A nrPDB 42 7e-04
3A26-A nrPDB 40 0.002
3CCF-A nrPDB 40 0.002
1EIZ-A nrPDB 40 0.003
3VSE-A nrPDB 39 0.004
2IPX-A nrPDB 38 0.007
1NT2-A nrPDB 38 0.009
2ZZN-A nrPDB 38 0.009
5WYK-3B nrPDB 38 0.012
3EEY-A nrPDB 38 0.012
6GKZ-A nrPDB 37 0.016
2ESR-A nrPDB 37 0.021
2IH5-A nrPDB 36 0.033
2B25-A nrPDB 36 0.035
2AUS-C nrPDB 36 0.040
4PON-A nrPDB 36 0.047
4DF3-A nrPDB 36 0.053
3CJR-A nrPDB 35 0.057
3TFW-A nrPDB 35 0.060
2CX0-A nrPDB 35 0.073
2OKC-A nrPDB 35 0.091
3UFB-A nrPDB 34 0.13
5KPG-A nrPDB 34 0.13
2FHP-A nrPDB 34 0.16
2YXD-A nrPDB 34 0.17
1KG4-A nrPDB 34 0.18
2NNW-B nrPDB 34 0.19
3BUS-A nrPDB 34 0.20
3HAY-A nrPDB 33 0.23
4BQH-A nrPDB 33 0.24
1I9G-A nrPDB 33 0.26
3LDF-A nrPDB 33 0.27
2IGT-A nrPDB 33 0.29
6ELZ-w nrPDB 32 0.53
3C3Y-A nrPDB 31 1.00
2PBF-A nrPDB 31 1.1
2J28-9 nrPDB 31 1.2
3BKX-A nrPDB 31 1.3
5VM2-A nrPDB 31 1.5
5LLK-A nrPDB 31 1.6
2GNO-A nrPDB 30 1.8
2HZ7-A nrPDB 30 1.9
1ULZ-A nrPDB 30 1.9
1P6U-A nrPDB 30 2.0
5WP5-A nrPDB 30 2.1
2EQA-A nrPDB 30 2.6
2GKS-A nrPDB 29 3.9
3ZV0-C nrPDB 29 4.3
5O9X-A nrPDB 29 6.0
>5WWT-A nrPDB
Length = 477
Score = 722 bits (1863), Expect = 0.0, Method: Composition-based stats.
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60
MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH
Sbjct: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60
Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120
LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC
Sbjct: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC 120
Query: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180
GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS
Sbjct: 121 GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS 180
Query: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240
RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD
Sbjct: 181 RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD 240
Query: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300
LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL
Sbjct: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300
Query: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360
DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ
Sbjct: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ 360
Query: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420
LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ
Sbjct: 361 LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ 420
Query: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469
LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST
Sbjct: 421 LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST 469
>5ZVG-B nrPDB
Length = 384
Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats.
Identities = 141/472 (29%), Positives = 222/472 (47%), Gaps = 95/472 (20%)
Query: 1 MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH 60
+ FPK E+ Y K F GK+EA + ++K L P +RVNT
Sbjct: 2 LEAFPK-----ELREYYKNLF---------GKEEANK----IMKKLREPVEHYYIRVNTL 43
Query: 61 LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPR--KNIKKQQCEAIVGA 118
S + L+ EL+K+ GL L+ P L + L GP + + + +
Sbjct: 44 KISREK----LIGELKKE--GLKP--LRSPYLPEGLYFVREGPNFSDDFEPKLPVVVANK 95
Query: 119 QCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISE 178
+V +GA +YAPG++ A + +K GD + + D KG + +G GI+
Sbjct: 96 YAAESVYQGAMLYAPGVLKADKNIKEGDEVQI-RDPKG-------------LLVGIGIAR 141
Query: 179 LSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLP---RYLFLQNLPSALVSHVLNPQPG 235
+ KE+ +G+ + +T P + PS + Y + Q LPS + + VL P+
Sbjct: 142 MDYKEMTEAT---RGLAVEVTLPKFKLPSLSELKAFEKGYFYPQGLPSMVTARVLEPKED 198
Query: 236 EKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGT 295
+ I+D+ AAPGGKTTHIA L+ ++GE+IA+DK N++ K+++N LG+ +++ D
Sbjct: 199 DVIIDMAAAPGGKTTHIAQLLENKGEIIAIDKSKNRLRKMEENIKRLGVKNVKLVQMDAR 258
Query: 296 KAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLF 355
K P L D+ILLDAPC+ +G RP + ++K + + QR
Sbjct: 259 KL-------------PDLGIKADKILLDAPCTALGVRPKLWEERTLKHIEATARYQRAFI 305
Query: 356 TAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSC 415
AA++ L+ GVLVYSTCT++ ENE V + + K ++L+ Q IG G+
Sbjct: 306 WAAIKSLRRGGVLVYSTCTLSYEENEGNVKFMIRK--GMKLEEQSIFIGSPGI------- 356
Query: 416 EQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCK 467
+ ++QRF P L + GFFIAK K K
Sbjct: 357 -GMNKVQRFYP--------------------HKHL----TQGFFIAKLRKVK 383
>6ELZ-q nrPDB
Length = 618
Score = 253 bits (645), Expect = 2e-67, Method: Composition-based stats.
Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 45/272 (16%)
Query: 201 PVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQG 260
P+ +P + L + LQ S L L+P E+ILD+ AAPGGKTT+I+A+M + G
Sbjct: 315 PIGATPEY---LAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTG 371
Query: 261 EVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRI 320
V A D ++ + + N LG + +D + P + FDRI
Sbjct: 372 CVFANDANKSRTKSLIANIHRLGCTNTIVCNYDAREF-------------PKVIGGFDRI 418
Query: 321 LLDAPCSG---MGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLL----KPEGVLVYSTC 373
LLDAPCSG +G+ ++ + + K+ LQ++L +A+ + K GV+VYSTC
Sbjct: 419 LLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTC 478
Query: 374 TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPD 433
++ + E+E + +AL K P ++L IG E + ++F P
Sbjct: 479 SVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSY--------RGKKFHP------- 523
Query: 434 TDMDSLREARREDMLRLANKDSIGFFIAKFVK 465
S++ ARR N D GFF+AKF K
Sbjct: 524 ----SVKLARRY-YPHTYNVD--GFFVAKFQK 548
>1IXK-A nrPDB
Length = 315
Score = 249 bits (634), Expect = 3e-66, Method: Composition-based stats.
Identities = 81/273 (29%), Positives = 127/273 (46%), Gaps = 45/273 (16%)
Query: 198 MTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMH 257
+T + S L +++Q S L+P+PGE + D+ AAPGGKT+++A LM
Sbjct: 82 LTREPFSITSTPEFLTGLIYIQEASSMYPPVALDPKPGEIVADMAAAPGGKTSYLAQLMR 141
Query: 258 DQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESF 317
+ G + A D N++ + + N LG+ ++ F +L++ F
Sbjct: 142 NDGVIYAFDVDENRLRETRLNLSRLGVLNVILFHSSSLHIGELNV-------------EF 188
Query: 318 DRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCT 374
D+ILLDAPC+G G + P ++ ++ Q LQ +L +++LKP G+LVYSTC+
Sbjct: 189 DKILLDAPCTGSGTIHKNPERKWNRTMDDIKFCQGLQMRLLEKGLEVLKPGGILVYSTCS 248
Query: 375 ITLAENEEQVAWALTKFPC--LQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLP 432
+ ENE + WAL F L L+ EP + G LS E++K +R P
Sbjct: 249 LEPEENEFVIQWALDNFDVELLPLKYGEPALTNPF--GIELS-EEIKNARRLYPDVH--- 302
Query: 433 DTDMDSLREARREDMLRLANKDSIGFFIAKFVK 465
++ GFFIAK K
Sbjct: 303 ---------------------ETSGFFIAKIRK 314
>2YXL-A nrPDB
Length = 450
Score = 211 bits (536), Expect = 7e-55, Method: Composition-based stats.
Identities = 64/188 (34%), Positives = 104/188 (55%), Gaps = 14/188 (7%)
Query: 214 RYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVE 273
+ +Q SA+ S VL+P+PGE ++DL AAPGGKTTH+A LM ++G++ A D +++
Sbjct: 239 GKIIVQEEASAVASIVLDPKPGETVVDLAAAPGGKTTHLAELMKNKGKIYAFDVDKMRMK 298
Query: 274 KIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGM---G 330
++K +G+ ++ D KA ++ E D++LLDAPC+ G
Sbjct: 299 RLKDFVKRMGIKIVKPLVKDARKAPEII-----------GEEVADKVLLDAPCTSSGTIG 347
Query: 331 QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK 390
+ P + ++ LQR+L +A +L+KP G L+Y+TC+I ENE+ + W L
Sbjct: 348 KNPELRWRLREDKINEMSQLQRELLESAARLVKPGGRLLYTTCSIFKEENEKNIRWFLNV 407
Query: 391 FPCLQLQP 398
P +L P
Sbjct: 408 HPEFKLVP 415
Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats.
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 15/99 (15%)
Query: 5 PKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASV 64
PK L YL ++ + + LG E E F ++ K H + ++RVNT A+V
Sbjct: 144 PKNELEELEWKYLAPSWLIERVKGILG-DETEDFFRSVNK--RH--EWISIRVNTLKANV 198
Query: 65 QHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGP 103
+ V + EL++ V +++ + +L I GP
Sbjct: 199 EEV----IGELEED----GVEVVRSERVPTILKI--KGP 227
>3AJD-A nrPDB
Length = 274
Score = 202 bits (512), Expect = 4e-52, Method: Composition-based stats.
Identities = 69/230 (30%), Positives = 112/230 (48%), Gaps = 17/230 (7%)
Query: 202 VYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGE 261
+ +P + L Y Q++ S + VLNP+ + ILD+CAAPGGKTTH+A LM ++G
Sbjct: 54 IGSTPEY---LFGYYMPQSISSMIPPIVLNPREDDFILDMCAAPGGKTTHLAQLMKNKGT 110
Query: 262 VIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRIL 321
++A++ + + +K N +G+ + D K + FD+IL
Sbjct: 111 IVAVEISKTRTKALKSNINRMGVLNTIIINADMRKYKDYLL---------KNEIFFDKIL 161
Query: 322 LDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENE 381
LDAPCSG + + S +++ Q++L + LLK +G LVYSTC++ + ENE
Sbjct: 162 LDAPCSGNIIK-DKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENE 220
Query: 382 EQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPL 431
E + + L K ++L I +G + +K R P P
Sbjct: 221 EVIKYILQKRNDVEL----IIIKANEFKGINIKEGYIKGTLRVFPPNEPF 266
>3M4X-A nrPDB
Length = 456
Score = 202 bits (512), Expect = 4e-52, Method: Composition-based stats.
Identities = 66/217 (30%), Positives = 108/217 (49%), Gaps = 16/217 (7%)
Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272
Y + Q + +V +PGEK+LDLCAAPGGK+T +AA M +G ++ + +
Sbjct: 84 AGYEYSQEPSAMIVGTAAAAKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRA 143
Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG-- 330
+ + +N G+++ T ++V P FDRI++DAPCSG G
Sbjct: 144 KILSENIERWGVSNAIV-----TNHAPAELV-------PHFSGFFDRIVVDAPCSGEGMF 191
Query: 331 -QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALT 389
+ PN W+ + Q Q+++ ++A+++LK +G L+YSTCT ENEE ++W +
Sbjct: 192 RKDPNAIKEWTEESPLYCQKRQQEILSSAIKMLKNKGQLIYSTCTFAPEENEEIISWLVE 251
Query: 390 KFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDP 426
+P + Q G R S L++ R P
Sbjct: 252 NYPVTIEEIPLTQSVSSG-RSEWGSVAGLEKTIRIWP 287
>2FRX-A nrPDB
Length = 479
Score = 200 bits (507), Expect = 1e-51, Method: Composition-based stats.
Identities = 71/277 (25%), Positives = 112/277 (40%), Gaps = 49/277 (17%)
Query: 197 RMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVL--NPQPGEKILDLCAAPGGKTTHIAA 254
P+ + L ++Q S L L + ++++D+ AAPG KTT I+A
Sbjct: 81 EDALPLGST---AEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQISA 137
Query: 255 LMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLP 314
M+++G ++A + ++V+ + N G++++ FDG +P
Sbjct: 138 RMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAA------------VP 185
Query: 315 ESFDRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYS 371
E FD ILLDAPCSG G + P+ WS + QR+L +A L+P G LVYS
Sbjct: 186 EMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYS 245
Query: 372 TCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPL 431
TCT+ ENE W +P F P
Sbjct: 246 TCTLNQEENEAVCLWLKETYP---------------------------DAVEFLPLGDLF 278
Query: 432 PDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKS 468
P + E ++ D GFF+A+ K ++
Sbjct: 279 PGANKALTEEGFLHVFPQIY--DCEGFFVARLRKTQA 313
>3M6U-A nrPDB
Length = 464
Score = 198 bits (503), Expect = 5e-51, Method: Composition-based stats.
Identities = 72/222 (32%), Positives = 102/222 (45%), Gaps = 25/222 (11%)
Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272
++Q + V +L+P+PGE++LDL AAPGGKTTH+AA M +G ++A + +V
Sbjct: 80 AGLYYIQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLANEVDGKRV 139
Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPES----FDRILLDAPCSG 328
+ +N G + T+ P L E+ F R+LLDAPCSG
Sbjct: 140 RGLLENVERWG-----------------APLAVTQAPPRALAEAFGTYFHRVLLDAPCSG 182
Query: 329 MG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVA 385
G + A W +Q+ L A +LL P GVLVYSTCT ENE VA
Sbjct: 183 EGMFRKDREAARHWGPSAPKRMAEVQKALLAQASRLLGPGGVLVYSTCTFAPEENEGVVA 242
Query: 386 WALTKFPCLQLQPQEPQ-IGGEGMRGAGLSCEQLKQLQRFDP 426
L P +L+ + G+ G +L + R P
Sbjct: 243 HFLKAHPEFRLEDARLHPLFAPGVPEWGEGNPELLKTARLWP 284
Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats.
Identities = 28/145 (19%), Positives = 45/145 (31%), Gaps = 31/145 (21%)
Query: 37 RKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNGLSVPILQH-PDLQDV 95
+F LK L+ +RVNT + F +S L+ P Q+
Sbjct: 16 EEFPAFLKALTEGKRTYGLRVNTLKLPPE------------AFQRISPWPLRPIPWCQEG 63
Query: 96 LLIPVI---GPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGD-VISVY 151
P GP G ++ A G++ K G+ V+ +
Sbjct: 64 FYYPEEARPGPHPFF-----------YAGLYYIQEPSAQAVGVL---LDPKPGERVLDLA 109
Query: 152 SDIKGKCKKGAKEFDGTKVFLGNGI 176
+ GK A G + L N +
Sbjct: 110 AAPGGKTTHLAARMGGKGLLLANEV 134
>1SQG-A nrPDB
Length = 429
Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats.
Identities = 67/225 (29%), Positives = 105/225 (46%), Gaps = 27/225 (12%)
Query: 196 IRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAAL 255
+ PV+ P F+ ++ +Q+ + L PQ GE ILDLCAAPGGKTTHI +
Sbjct: 211 LETPAPVHALPGFED---GWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEV 267
Query: 256 MHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL-- 313
+ +V+A+D ++ ++ N LG+ + V+ +G P
Sbjct: 268 -APEAQVVAVDIDEQRLSRVYDNLKRLGMKAT---------------VKQGDGRYPSQWC 311
Query: 314 -PESFDRILLDAPCSGMG---QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLV 369
+ FDRILLDAPCS G + P++ +++ LQ ++ A LK G LV
Sbjct: 312 GEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLV 371
Query: 370 YSTCTITLAENEEQVAWALTKFPCLQLQPQEP--QIGGEGMRGAG 412
Y+TC++ EN Q+ L + +L Q G + + GA
Sbjct: 372 YATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAE 416
>2B9E-A nrPDB
Length = 309
Score = 186 bits (472), Expect = 2e-47, Method: Composition-based stats.
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272
+L LQ+ S L + +L+P PG ++D CAAPG KT+H+AAL+ +QG++ A D
Sbjct: 81 AGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGKIFAFDLDA--- 137
Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG-- 330
+++ A LL + + + D + + +P + ILLD CSG G
Sbjct: 138 KRLASMATLLARAGVSC-----CELAEEDFLAVSPSDPRY--HEVHYILLDPSCSGSGMP 190
Query: 331 ----QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPE-GVLVYSTCTITLAENEEQVA 385
+ P V+ A QR L A L P LVYSTC++ ENE+ V
Sbjct: 191 SRQLEEPGAGTPSPVRLHALAGFQQRALCHA---LTFPSLQRLVYSTCSLCQEENEDVVR 247
Query: 386 WALTKFPC-LQLQPQEPQIGGEGM 408
AL + P +L P P G+
Sbjct: 248 DALQQNPGAFRLAPALPAWPHRGL 271
>4FZV-A nrPDB
Length = 359
Score = 151 bits (382), Expect = 5e-37, Method: Composition-based stats.
Identities = 57/190 (30%), Positives = 88/190 (46%), Gaps = 34/190 (17%)
Query: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT---------THIAALMHDQGEVIALD 266
+L + S L L QPG+ +LDLCAAPGGKT ++AA + L
Sbjct: 130 YYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQ 189
Query: 267 KIFNKV--EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324
KI + E+I+ N +R +DG K +L+ +++DR+L+D
Sbjct: 190 KILHSYVPEEIRDG------NQVRVTSWDGRKWGELE------------GDTYDRVLVDV 231
Query: 325 PCS----GMGQRPNMACTWSVKEVASYQP-LQRKLFTAAVQLLKPEGVLVYSTCTITLAE 379
PC+ + + N S K+ P LQ +L A + KP G +VYSTC+++ +
Sbjct: 232 PCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQ 291
Query: 380 NEEQVAWALT 389
NE V A+
Sbjct: 292 NEYVVQGAIE 301
>1WXW-A nrPDB
Length = 382
Score = 118 bits (295), Expect = 5e-27, Method: Composition-based stats.
Identities = 47/203 (23%), Positives = 84/203 (41%), Gaps = 33/203 (16%)
Query: 188 LPELKGMGIRMTEPVYLSPSFDSVLPRYL-FLQN-LPSALVSHVLNPQP---------GE 236
EL+G+ + + + P V + +L + L+ + GE
Sbjct: 152 TRELEGLPLYVRPLLGEVPERVQVQEGRVRYLVDLRAGQKTGAYLDQRENRLYMERFRGE 211
Query: 237 KILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTK 296
+ LD+ + GG H+A EV+A+D + + ++NA L GL ++R +
Sbjct: 212 RALDVFSYAGGFALHLALGFR---EVVAVDSSAEALRRAEENARLNGLGNVRVL-----E 263
Query: 297 AVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356
A D++ E E E FD ++LD P G++ + KEV
Sbjct: 264 ANAFDLLRRLEKE----GERFDLVVLDPPAFAKGKKDVERAYRAYKEVN----------L 309
Query: 357 AAVQLLKPEGVLVYSTCTITLAE 379
A++LLK G+L ++C+ + E
Sbjct: 310 RAIKLLKEGGILATASCSHHMTE 332
>2AS0-A nrPDB
Length = 396
Score = 117 bits (293), Expect = 9e-27, Method: Composition-based stats.
Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 20/146 (13%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
QPG+++LD+ GG H A D EVI +DK +E K+NA L G+ F
Sbjct: 216 QPGDRVLDVFTYTGGFAIHAAIAGAD--EVIGIDKSPRAIETAKENAKLNGVEDRMKFIV 273
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
G+ +++ ++ E FD ++LD P A K++ +
Sbjct: 274 -GSAFEEMEKLQKK-------GEKFDIVVLDPP----------AFVQHEKDLKAGLRAYF 315
Query: 353 KLFTAAVQLLKPEGVLVYSTCTITLA 378
+ A + L+K G+LV +C+ +
Sbjct: 316 NVNFAGLNLVKDGGILVTCSCSQHVD 341
Score = 36.0 bits (81), Expect = 0.041, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 114 AIVGAQCGNAVLRGAH-VYAPGIVSASQFMKAGDVISVYS 152
+V AQ A+ +GA V+ G+V +K GD++ VY+
Sbjct: 4 VVVDAQAARAIGKGAMIVFKKGVVRVEGDIKPGDIVEVYT 43
>3C0K-A nrPDB
Length = 396
Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats.
Identities = 30/163 (18%), Positives = 59/163 (36%), Gaps = 22/163 (13%)
Query: 212 LPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNK 271
Y Q + +++L+ + GG ++ALM +V+++D
Sbjct: 201 KTGYYLDQRDSRLATRRYV---ENKRVLNCFSYTGGFA--VSALMGGCSQVVSVDTSQEA 255
Query: 272 VEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQ 331
++ +QN L + V+ D+ + E FD I++D P +
Sbjct: 256 LDIARQNVELN------KLDLSKAEFVRDDVFKLLRT-YRDRGEKFDVIVMDPPKFVENK 308
Query: 332 RPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCT 374
M K++ A+QLL G+L+ +C+
Sbjct: 309 SQLMGACRGYKDINML----------AIQLLNEGGILLTFSCS 341
>4DMG-A nrPDB
Length = 393
Score = 61.4 bits (147), Expect = 7e-10, Method: Composition-based stats.
Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 26/144 (18%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+PGE++LD+ + GG A +A+DK + + Q AL LGL
Sbjct: 213 RPGERVLDVYSYVGGFALRAA---RKGAYALAVDKDLEALGVLDQAALRLGLR------V 263
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
D L + EG F +LLD P +E+ + +
Sbjct: 264 DIRHGEALPTLRGLEGP-------FHHVLLDPP----------TLVKRPEELPAMKRHLV 306
Query: 353 KLFTAAVQLLKPEGVLVYSTCTIT 376
L A++LL EG L S+C+
Sbjct: 307 DLVREALRLLAEEGFLWLSSCSYH 330
>1UWV-A nrPDB
Length = 433
Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats.
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288
L+ QP +++LDL G T +A V+ ++ + VEK +QNA L GL ++
Sbjct: 281 WLDVQPEDRVLDLFCGMGNFTLPLATQAAS---VVGVEGVPALVEKGQQNARLNGLQNVT 337
Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324
+ + +E+ + P+ FD++LLD
Sbjct: 338 FYH---------ENLEEDVTKQPWAKNGFDKVLLDP 364
>1O54-A nrPDB
Length = 277
Score = 49.5 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 53/317 (16%), Positives = 101/317 (31%), Gaps = 63/317 (19%)
Query: 137 SASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGI 196
+ +K GD + + + + + ++ LG + E+F P G I
Sbjct: 15 KVADTLKPGDRVLLSFEDESEFLVDLEKDKKLHTHLGI----IDLNEVFEKGP---GEII 67
Query: 197 RMTEPVY---LSPSFDS----VLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT 249
R + L PS + R + S+ ++ +L+ + G++I+D G
Sbjct: 68 RTSAGKKGYILIPSLIDEIMNMKRRTQIVYPKDSSFIAMMLDVKEGDRIIDTGVGSGAMC 127
Query: 250 THIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGE 309
+A + G+V A +K + + N GL ++ ++ +
Sbjct: 128 AVLARAVGSSGKVFAYEKREEFAKLAESNLTKWGL-------------IERVTIKVRDIS 174
Query: 310 PPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLV 369
F + D + LD P W+ + LK G
Sbjct: 175 EGFDEKDVDALFLDVP-----------DPWNY-------------IDKCWEALKGGGRFA 210
Query: 370 YSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAV 429
T+ N QV L K L ++ R E+L+ + R V
Sbjct: 211 ----TVCPTTN--QVQETLKKLQELPFI--RIEVWESLFRPYKPVPERLRPVDRM----V 258
Query: 430 PLPDTDMDSLREARRED 446
+ + + RRE+
Sbjct: 259 AHTAYMIFATKVCRREE 275
>3TMA-A nrPDB
Length = 354
Score = 49.1 bits (115), Expect = 5e-06, Method: Composition-based stats.
Identities = 34/150 (22%), Positives = 51/150 (34%), Gaps = 24/150 (16%)
Query: 223 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLL 282
+ + + + +PG ++LD G A+ + V A D ++ ++ AL
Sbjct: 192 AQALLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLAREAALAS 251
Query: 283 GLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVK 342
GL+ IR D P F PE DRIL + P G R
Sbjct: 252 GLSWIRFLRADARHL------------PRFFPE-VDRILANPP---HGLRLGRK------ 289
Query: 343 EVASYQPLQRKLFTAAVQLLKPEGVLVYST 372
L A+ LL P G + T
Sbjct: 290 --EGLFHLYWDFLRGALALLPPGGRVALLT 317
>3V8V-A nrPDB
Length = 702
Score = 47.9 bits (112), Expect = 8e-06, Method: Composition-based stats.
Identities = 29/137 (21%), Positives = 50/137 (36%), Gaps = 20/137 (14%)
Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294
G+ L+L + G T H A + +D +E ++N L GL
Sbjct: 539 GKDFLNLFSYTGSATVH--AGLGGARSTTTVDMSRTYLEWAERNLRLNGLTGR------A 590
Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKL 354
+ ++ D + E FD I +D P +R A +A + L+R
Sbjct: 591 HRLIQADCLAWL----REANEQFDLIFIDPPTFSNSKRMEDAFDVQRDHLALMKDLKR-- 644
Query: 355 FTAAVQLLKPEGVLVYS 371
LL+ G +++S
Sbjct: 645 ------LLRAGGTIMFS 655
>3A27-A nrPDB
Length = 272
Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats.
Identities = 22/132 (16%), Positives = 44/132 (33%), Gaps = 3/132 (2%)
Query: 188 LPELKGMGIRMTEPVYLSPS--FDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAP 245
P +K + + TE ++ F + + ++ Q E ++D+ A
Sbjct: 71 TPHVKILYGKETETIHKEYGCLFKLDVAKIMWSQGNIEERKRMAFISNENEVVVDMFAGI 130
Query: 246 GGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVED 305
G T +A + V A++K + +N L LN++ D D+ +
Sbjct: 131 GYFTIPLAKYSKPK-LVYAIEKNPTAYHYLCENIKLNKLNNVIPILADNRDVELKDVADR 189
Query: 306 TEGEPPFLPESF 317
F
Sbjct: 190 VIMGYVHKTHKF 201
>3D79-A nrPDB
Length = 179
Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats.
Identities = 26/118 (22%), Positives = 50/118 (42%), Gaps = 18/118 (15%)
Query: 83 SVPILQHPDL--QDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQ 140
++ DL V+ + + ++++K +V +L GA V APGIV A +
Sbjct: 64 KPMFIRRKDLIFPLVIALYNLSDEEDLRKWPRRVVVDEGAVPHILNGADVMAPGIVDADE 123
Query: 141 FMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRM 198
+K GD + V + G+ L GI+ +S K + + +G +++
Sbjct: 124 GIKEGDFVFVVEEKYGRP-------------LAIGIALMSGKVMKE---KNRGKAVKV 165
>5YAC-A nrPDB
Length = 346
Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats.
Identities = 14/67 (20%), Positives = 27/67 (40%), Gaps = 3/67 (4%)
Query: 232 PQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFC 291
Q GE + D+ A G + +A V A D ++ +++N L +N++
Sbjct: 196 AQEGEVVFDMFAGVGPFSILLA---KKAELVFACDINPWAIKYLEENIKLNKVNNVVPIL 252
Query: 292 FDGTKAV 298
D +
Sbjct: 253 GDSREIE 259
>1Q7H-A nrPDB
Length = 153
Score = 44.9 bits (104), Expect = 8e-05, Method: Composition-based stats.
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 24/121 (19%)
Query: 79 FNGLSVPILQHPDL-QDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVS 137
+ G + Q DL V L+ P +NI V +L G+ ++APGIVS
Sbjct: 43 YIGGKPMVFQAGDLIPSVYLLNYRNPSRNI------VTVDEGAEPHILNGSDLFAPGIVS 96
Query: 138 ASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIR 197
++ GD+I V S KG F+ G++E+ E+ + +G R
Sbjct: 97 MDDSIRKGDMIFVKSS-KGY-------------FIAVGMAEMDAGEV---MATKRGKAAR 139
Query: 198 M 198
+
Sbjct: 140 I 140
>2VS1-A nrPDB
Length = 425
Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats.
Identities = 27/140 (19%), Positives = 49/140 (35%), Gaps = 42/140 (30%)
Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFD 293
GEKILD+ + G ++A + V D +E ++N + ++
Sbjct: 290 EGEKILDMYSGVGTFGIYLAKRGFN---VKGFDSNEFAIEMARRNVEINNVD-------- 338
Query: 294 GTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRK 353
+ ++ D E + FD +++D P +G+ R
Sbjct: 339 ----AEFEVASDREVSV----KGFDTVIVDPPRAGLHPRLVKRLNRE------------- 377
Query: 354 LFTAAVQLLKPEGVLVYSTC 373
KP GV+VY +C
Sbjct: 378 ---------KP-GVIVYVSC 387
>5OQL-R nrPDB
Length = 313
Score = 42.2 bits (97), Expect = 5e-04, Method: Composition-based stats.
Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+PG K+L L AA G +H+A ++ G V A++ + A ++
Sbjct: 151 KPGSKVLYLGAASGTSVSHVADIVGPTGAVYAVEFSHRSGRDLINMATR--RTNVIPIVE 208
Query: 293 DGTKAVKLDMV 303
D K + M+
Sbjct: 209 DARKPMAYRML 219
>2PWY-A nrPDB
Length = 258
Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats.
Identities = 12/73 (16%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIK 276
+ ++ + + +L+ PG ++L+ GG T +A + ++G V + + + + + +
Sbjct: 81 YPKDASAMV--TLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAE 138
Query: 277 QNAL-LLGLNSIR 288
+N + ++R
Sbjct: 139 RNVRAFWQVENVR 151
>3A26-A nrPDB
Length = 301
Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 16/91 (17%), Positives = 35/91 (38%), Gaps = 3/91 (3%)
Query: 228 HVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSI 287
+P E ++D+ A G + IA ++ + +VIA++K + + +N L +
Sbjct: 142 MAKVAKPDELVVDMFAGIGHLSLPIA--VYGKAKVIAIEKDPYTFKFLVENIHLNKVEDR 199
Query: 288 R-AFCFDGTKAVKLDMVEDTEGEPPFLPESF 317
A+ D ++ + F
Sbjct: 200 MSAYNMDNRDFPGENIADRILMGYVVRTHEF 230
>3CCF-A nrPDB
Length = 279
Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats.
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQN 278
+LNPQPGE ILDL G T IA EV+ D +EK +QN
Sbjct: 52 LLNPQPGEFILDLGCGTGQLTEKIAQSG---AEVLGTDNAATMIEKARQN 98
>1EIZ-A nrPDB
Length = 180
Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 23/39 (58%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNK 271
+PG ++DL AAPGG + ++ + +G +IA D +
Sbjct: 21 KPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMD 59
>3VSE-A nrPDB
Length = 398
Score = 39.1 bits (89), Expect = 0.004, Method: Composition-based stats.
Identities = 28/136 (20%), Positives = 44/136 (32%), Gaps = 20/136 (14%)
Query: 237 KILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTK 296
+L+L + G + A+ V D ++N GLN+I
Sbjct: 217 HVLNLFSYTGAFSVIAASEASSTTSV---DLANRSRSLTEEN---FGLNAIDPKSQYIYV 270
Query: 297 AVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356
D + S+D I++D P + K S Q KL
Sbjct: 271 MDTFDFYKYAARH----GHSYDTIVIDPPSFA----------RNKKRTFSVQKDYDKLIN 316
Query: 357 AAVQLLKPEGVLVYST 372
A+ +L EG L+ T
Sbjct: 317 GALNILSSEGTLLLCT 332
>2IPX-A nrPDB
Length = 233
Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats.
Identities = 35/172 (20%), Positives = 54/172 (31%), Gaps = 38/172 (22%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+PG K+L L AA G +H++ ++ G V A++ + A +I
Sbjct: 76 KPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKK--RTNIIPVIE 133
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
D + L D I D QP Q
Sbjct: 134 DARH----------PHKYRMLIAMVDVIFADV----------------------AQPDQT 161
Query: 353 KLFT-AAVQLLKPEGVLVYS---TCTITLAENEEQVAWALTKFPCLQLQPQE 400
++ A L+ G V S C + A E A + K ++PQE
Sbjct: 162 RIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQE 213
>1NT2-A nrPDB
Length = 210
Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats.
Identities = 31/158 (19%), Positives = 62/158 (39%), Gaps = 11/158 (6%)
Query: 221 LPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNAL 280
L H L + E++L L AA G +H+A ++ D+G + A++ EK+ +
Sbjct: 44 AAMILKGHRLKLRGDERVLYLGAASGTTVSHLADIV-DEGIIYAVEYSAKPFEKLLELVR 102
Query: 281 LLGLNSIRAFCFDGTK-AVKLDMVEDTEGEPPFLPESFDRILLDAPC----SGMGQRPNM 335
N+I FD +K +VE + + + +L A G+ M
Sbjct: 103 E--RNNIIPLLFDASKPWKYSGIVEKVDLIYQDIAQKNQIEILKANAEFFLKEKGEVVIM 160
Query: 336 ACTWSVKEVASYQPLQRKLF---TAAVQLLKPEGVLVY 370
S+ A + + + + +++K ++ Y
Sbjct: 161 VKARSIDSTAEPEEVFKSVLKEMEGDFKIVKHGSLMPY 198
>2ZZN-A nrPDB
Length = 336
Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats.
Identities = 15/87 (17%), Positives = 32/87 (36%), Gaps = 4/87 (4%)
Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294
+ ++D+ A G + + ++ A+D + +E +K+N L L
Sbjct: 196 NDVVVDMFAGVGPFSI----ACKNAKKIYAIDINPHAIELLKKNIKLNKLEHKIIPILSD 251
Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRIL 321
+ V + P F + D+ L
Sbjct: 252 VREVDVKGNRVIMNLPKFAHKFIDKAL 278
>5WYK-3B nrPDB
Length = 327
Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFD 293
PG+K+L L AA G +H++ ++ +G V A++ ++ A +I D
Sbjct: 166 PGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKK--RPNIIPIIED 223
Query: 294 GTKAVKLDMV 303
K M+
Sbjct: 224 ARHPQKYRML 233
>3EEY-A nrPDB
Length = 197
Score = 37.5 bits (85), Expect = 0.012, Method: Composition-based stats.
Identities = 24/158 (15%), Positives = 50/158 (31%), Gaps = 24/158 (15%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+ G+ ++D G T +A+L+ + G V D + + L L
Sbjct: 21 KEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIK 80
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
DG + D + P F+ L +++
Sbjct: 81 DGHQ------NMDKYIDCPVKAVMFNLGYL---------------PSGDHSISTRPETTI 119
Query: 353 KLFTAAVQLLKPEGVL---VYSTCTITLAENEEQVAWA 387
+ + A++LL G++ +Y E E+ + +
Sbjct: 120 QALSKAMELLVTGGIITVVIYYGGDTGFEEKEKVLEFL 157
>6GKZ-A nrPDB
Length = 351
Score = 37.2 bits (84), Expect = 0.016, Method: Composition-based stats.
Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 15/90 (16%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
Q G+ +LDL G T H+A + V A+ ++ E I++ + L ++
Sbjct: 122 QDGQSVLDLGCGQGALTLHVAQKYKN-CRVTAVTNSVSQKEYIEEESRRRNLLNVEVKLA 180
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILL 322
D T + E++DRIL+
Sbjct: 181 DITTHE--------------MAETYDRILV 196
>2ESR-A nrPDB
Length = 177
Score = 36.8 bits (83), Expect = 0.021, Method: Composition-based stats.
Identities = 19/92 (20%), Positives = 32/92 (34%), Gaps = 13/92 (14%)
Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFD 293
G ++LDL A GG I A+ + ++K I+ N ++ +
Sbjct: 31 NGGRVLDLFAGSGGLA--IEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTL--- 85
Query: 294 GTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325
+ + E L FD + LD P
Sbjct: 86 --------LKMEAERAIDCLTGRFDLVFLDPP 109
>2IH5-A nrPDB
Length = 421
Score = 36.0 bits (81), Expect = 0.033, Method: Composition-based stats.
Identities = 35/188 (18%), Positives = 61/188 (32%), Gaps = 37/188 (19%)
Query: 193 GMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHI 252
G+ ++ P +P L R + +VS P+ G ++L+ A G
Sbjct: 2 GLPPLLSLPSNSAP---RSLGRVETPPEVVDFMVSLAEAPR-GGRVLEPACAHGPFLRAF 57
Query: 253 AALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPF 312
+ ++ + D + + + EP
Sbjct: 58 REAHGTAYRFVGVEIDPKAL--------------------DLPPWAEGILADFLLWEP-- 95
Query: 313 LPESFDRILLDAP--CSGMGQRPNMACTWSVKEV--------ASYQPLQRKLFTAAVQLL 362
E+FD IL + P G + + +VK++ L AV+LL
Sbjct: 96 -GEAFDLILGNPPYGIVGEASKYPIHVFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLL 154
Query: 363 KPEGVLVY 370
KP GVLV+
Sbjct: 155 KPGGVLVF 162
>2B25-A nrPDB
Length = 336
Score = 36.0 bits (81), Expect = 0.035, Method: Composition-based stats.
Identities = 18/96 (18%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288
+++ PG+ +L+ + GG + ++ + QG VI+ + + + K+N +S +
Sbjct: 100 MMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHW-RDSWK 158
Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPE-SFDRILLD 323
+ + +D G + +FD + LD
Sbjct: 159 LSHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALD 194
>2AUS-C nrPDB
Length = 334
Score = 36.0 bits (81), Expect = 0.040, Method: Composition-based stats.
Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 101 IGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKK 160
I P + + + + AV GA++ PGIV + +K GD++++ +
Sbjct: 240 IQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMT-------- 291
Query: 161 GAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRM 198
+ G + +S +E+ KG+ + +
Sbjct: 292 ------LKDELVALGKAMMSTQEMIE---RSKGIAVDV 320
>4PON-A nrPDB
Length = 200
Score = 35.6 bits (80), Expect = 0.047, Method: Composition-based stats.
Identities = 15/70 (21%), Positives = 24/70 (34%)
Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA 289
+ G+ ++D G T +A L+ + G V A D + V K+
Sbjct: 22 MAAGEGDIVIDATMGNGHDTQFLAELVGENGHVYAFDIQESAVANTKERLGEAYQARTTL 81
Query: 290 FCFDGTKAVK 299
F K K
Sbjct: 82 FHKSHDKIAK 91
>4DF3-A nrPDB
Length = 233
Score = 35.6 bits (80), Expect = 0.053, Method: Composition-based stats.
Identities = 15/105 (14%), Positives = 34/105 (32%), Gaps = 13/105 (12%)
Query: 221 LPSALVSHVLNP-QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNA 279
+ L + P + G++IL L A G +H++ ++ +G + ++ +
Sbjct: 63 AAALLKGLIELPVKEGDRILYLGIASGTTASHMSDIIGPRGRIYGVEFAPRVMR------ 116
Query: 280 LLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324
+ D + + L E D + D
Sbjct: 117 ------DLLTVVRDRRNIFPILGDARFPEKYRHLVEGVDGLYADV 155
>3CJR-A nrPDB
Length = 254
Score = 35.2 bits (79), Expect = 0.057, Method: Composition-based stats.
Identities = 15/61 (24%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Query: 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG 283
AL + + +PG+K+LDL G A G+ + +D + + + NA G
Sbjct: 110 ALKALARHLRPGDKVLDLGTGSGVLAI---AAEKLGGKALGVDIDPMVLPQAEANAKRNG 166
Query: 284 L 284
+
Sbjct: 167 V 167
>3TFW-A nrPDB
Length = 248
Score = 35.2 bits (79), Expect = 0.060, Method: Composition-based stats.
Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 10/113 (8%)
Query: 212 LPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNK 271
LP + N L + ++ ++IL++ G T +A + G+++ L+ +
Sbjct: 42 LPAHDVAANQGQFL-ALLVRLTQAKRILEIGTLGGYSTIWMARELPADGQLLTLEADAHH 100
Query: 272 VEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324
+ ++N L G++ R +G L+ + + FD I +DA
Sbjct: 101 AQVARENLQLAGVDQ-RVTLREGPALQSLESLGECPA--------FDLIFIDA 144
>2CX0-A nrPDB
Length = 187
Score = 34.8 bits (78), Expect = 0.073, Method: Composition-based stats.
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 113 EAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVI-SVYSDIKGKCKKGAKEFDGTKV 170
+V A+ +GAH+ PG+V GDV+ ++Y + + G E D + +
Sbjct: 94 VVLVDKGAAIALAKGAHLMIPGVVGVEGSFTRGDVVAALYHETRTPVMVGVAEVDSSAL 152
>2OKC-A nrPDB
Length = 445
Score = 34.8 bits (78), Expect = 0.091, Method: Composition-based stats.
Identities = 32/166 (19%), Positives = 50/166 (30%), Gaps = 24/166 (14%)
Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272
F + +NPQ GE + D GG M Q K
Sbjct: 150 AGQYFTPRPLIQAMVDCINPQMGETVCDPACGTGGFLLTAYDYMKGQS------ASKEKR 203
Query: 273 EKIKQNALLLGLNSIRA----------FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILL 322
+ ++ A L G+++ GT + + E EP L D IL
Sbjct: 204 DFLRDKA-LHGVDNTPLVVTLASMNLYLHGIGTDRSPIVCEDSLEKEPSTL---VDVILA 259
Query: 323 DAPCSGMGQRPNMACTWSVKEV-ASYQPLQRKLFTAAVQLLKPEGV 367
+ P G RP + + + + Q + +LK G
Sbjct: 260 NPP---FGTRPAGSVDINRPDFYVETKNNQLNFLQHMMLMLKTGGR 302
>3UFB-A nrPDB
Length = 530
Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats.
Identities = 33/195 (16%), Positives = 64/195 (32%), Gaps = 11/195 (5%)
Query: 174 NGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQ 233
NGI S +E+ + + M M + S F + P F+ V++PQ
Sbjct: 165 NGIHFNSSEEMHTLSRLYETMLREMRDAAGDSGEFYTPRPVVRFMVE--------VMDPQ 216
Query: 234 PGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA-FCF 292
GE +LD GG + Q + + ++ + A L ++
Sbjct: 217 LGESVLDPACGTGGFLVEAFEHLERQCKTVEDREVLQESSIFGGEAKSLPYLLVQMNLLL 276
Query: 293 DGTKAVKLDMVEDTEGEPPFLPES--FDRILLDAPCSGMGQRPNMACTWSVKEVASYQPL 350
G + ++D + + D IL + P G ++ + + A L
Sbjct: 277 HGLEYPRIDPENSLRFPLREMGDKDRVDVILTNPPFGGEEEKGILGNFPEDMQTAETAML 336
Query: 351 QRKLFTAAVQLLKPE 365
+L ++
Sbjct: 337 FLQLIMRKLKRPGHG 351
>5KPG-A nrPDB
Length = 397
Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats.
Identities = 33/166 (19%), Positives = 56/166 (33%), Gaps = 5/166 (3%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+ G+ ILDL G T H+A +V + ++ E I L L+++
Sbjct: 167 KDGQSILDLGCGHGSLTLHVAQKYRG-CKVTGITNSVSQKEFIMDQCKKLDLSNVEIILE 225
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQR 352
D TK + + L + + Q + +V +YQ
Sbjct: 226 DVTKFETEITYDRIFAVALIEHMKNYELFLKKVSTWIAQDGLLFVEHHCHKVFAYQYEPL 285
Query: 353 KLFTAAVQLLKPEGVLVYSTCTI---TLAENEEQVAWALT-KFPCL 394
+ + P G LV S+ +I + W L+ K P L
Sbjct: 286 DEDDWYTEYIFPSGTLVMSSSSILLYFQEDVSVVNHWTLSGKHPSL 331
>2FHP-A nrPDB
Length = 187
Score = 33.7 bits (75), Expect = 0.16, Method: Composition-based stats.
Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 12/92 (13%)
Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294
G LDL + GG + D+ I ++K F ++ IK+N A +
Sbjct: 45 GGMALDLYSGSGGLAIEAVSRGMDKS--ICIEKNFAALKVIKENI---------AITKEP 93
Query: 295 TKAVKLDMVEDTEGEPPFLPE-SFDRILLDAP 325
K M + E + + FD +LLD P
Sbjct: 94 EKFEVRKMDANRALEQFYEEKLQFDLVLLDPP 125
>2YXD-A nrPDB
Length = 183
Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats.
Identities = 19/75 (25%), Positives = 29/75 (38%), Gaps = 5/75 (6%)
Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA 289
LN + ++D+ GG T IA V A+D + +E KQN + +
Sbjct: 31 LNLNKDDVVVDVGCGSGGMTVEIAKRCK---FVYAIDYLDGAIEVTKQNLAKFNIKN--C 85
Query: 290 FCFDGTKAVKLDMVE 304
G LD +E
Sbjct: 86 QIIKGRAEDVLDKLE 100
>1KG4-A nrPDB
Length = 225
Score = 33.7 bits (75), Expect = 0.18, Method: Composition-based stats.
Identities = 28/169 (16%), Positives = 54/169 (31%), Gaps = 18/169 (10%)
Query: 238 ILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKA 297
+ DL AP + H+ + L K +V + + A G
Sbjct: 62 VTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRST 121
Query: 298 VKLDMVEDTEGEPPFLPESFDRILLDAPCSGM----GQRPNMACTWSVKEVASYQPLQRK 353
+ P L + R+L A C + G++ WS+ E + +
Sbjct: 122 AGAILSLSLGKHFPILDGNVARVL--ARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVER 179
Query: 354 LFTAAVQLLKPEGVLVYST---CTITLAEN----EEQVAWALTKFPCLQ 395
A + L ++ + C++ +N +WAL +P +
Sbjct: 180 FNQAMMDL---GAMICTRSKPKCSLCPLQNGCIAAANNSWAL--YPGKK 223
>2NNW-B nrPDB
Length = 234
Score = 33.7 bits (75), Expect = 0.19, Method: Composition-based stats.
Identities = 13/92 (14%), Positives = 32/92 (34%), Gaps = 12/92 (13%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCF 292
+PG+ +L L A G +H++ ++ +G++ ++ + ++
Sbjct: 79 KPGKSVLYLGIASGTTASHVSDIVGWEGKIYGIEFSPRVLREL------------VPIVE 126
Query: 293 DGTKAVKLDMVEDTEGEPPFLPESFDRILLDA 324
+ + + E L D I D
Sbjct: 127 ERRNIIPILGDATKPEEYRALVTKVDVIFEDV 158
>3BUS-A nrPDB
Length = 273
Score = 33.7 bits (75), Expect = 0.20, Method: Composition-based stats.
Identities = 24/141 (17%), Positives = 47/141 (33%), Gaps = 33/141 (23%)
Query: 229 VLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288
+L+ + G+++LD+ G +A V + +V + A GL +
Sbjct: 56 LLDVRSGDRVLDVGCGIGKPAVRLAT--ARDVRVTGISISRPQVNQANARATAAGLANRV 113
Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQ 348
F + + PF SFD + W+++ +
Sbjct: 114 TFSY------------ADAMDLPFEDASFDAV------------------WALESLHHMP 143
Query: 349 PLQRKLFTAAVQLLKPEGVLV 369
R L A ++L+P G +
Sbjct: 144 DRGRALREMA-RVLRPGGTVA 163
>3HAY-A nrPDB
Length = 346
Score = 33.3 bits (74), Expect = 0.23, Method: Composition-based stats.
Identities = 16/98 (16%), Positives = 36/98 (36%), Gaps = 17/98 (17%)
Query: 101 IGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKK 160
I P + + + + AV GA + PGI +K GD++++ +
Sbjct: 240 IQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMT-------- 291
Query: 161 GAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRM 198
+ G + ++ +E+ KG+ + +
Sbjct: 292 ------LKDELVALGKAMMTSQEMLEKT---KGIAVDV 320
>4BQH-A nrPDB
Length = 549
Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats.
Identities = 28/140 (20%), Positives = 48/140 (34%), Gaps = 9/140 (6%)
Query: 241 LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL 300
+CAAPGG AAL + D E + Q+ LG+ ++ D A
Sbjct: 231 ICAAPGGNGAVFAALAAPRAT-KDKDGTLQVKESLLQHLRKLGIAYVQIGNIDNLLANVA 289
Query: 301 DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPN----MACTWSVKEVASYQPLQRKLFT 356
D V + E ++ P G +R + W V E +++
Sbjct: 290 DPVFIGYA----IEEEAHVVVKTCPKRGPDERVGVFVRASGKWGVVEYTEIGDRAKEIDD 345
Query: 357 AAVQLLKPEGVLVYSTCTIT 376
A +L + + C++
Sbjct: 346 ATGELKFNCANISSNLCSLH 365
>1I9G-A nrPDB
Length = 280
Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats.
Identities = 30/159 (18%), Positives = 55/159 (34%), Gaps = 37/159 (23%)
Query: 213 PRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKV 272
P+ ++ ++ + H + PG ++L+ A G T + + G+VI+ ++ +
Sbjct: 80 PQVIYPKDAAQIV--HEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVISYEQRADHA 137
Query: 273 EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQR 332
E ++N G +V + S DR +LD
Sbjct: 138 EHARRNVSGC----------YGQPPDNWRLVVSDLADSELPDGSVDRAVLD--------- 178
Query: 333 PNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVL-VY 370
M W ++ A +LL GVL VY
Sbjct: 179 --MLAPW-------------EVLDAVSRLLVAGGVLMVY 202
>3LDF-A nrPDB
Length = 385
Score = 32.9 bits (73), Expect = 0.27, Method: Composition-based stats.
Identities = 25/138 (18%), Positives = 46/138 (33%), Gaps = 19/138 (13%)
Query: 235 GEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDG 294
G+ +L+L + + A + L K + A L + + + D
Sbjct: 213 GKTVLNLFSYTAAFSVAAAMGGAMATTSVDLAKRSRALSLAHFEANHLDMANHQLVVMD- 271
Query: 295 TKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKL 354
V D ++D I++D P + KEV S KL
Sbjct: 272 --------VFDYFKYARRHHLTYDIIIIDPPSFA----------RNKKEVFSVSKDYHKL 313
Query: 355 FTAAVQLLKPEGVLVYST 372
+++L G+++ ST
Sbjct: 314 IRQGLEILSENGLIIAST 331
>2IGT-A nrPDB
Length = 332
Score = 32.9 bits (73), Expect = 0.29, Method: Composition-based stats.
Identities = 21/98 (21%), Positives = 36/98 (36%), Gaps = 13/98 (13%)
Query: 261 EVIALDKIFNKVEKIKQNALLLGLNS--IRAFCFDGTKAVKLDMVEDTEGEPPFLPESFD 318
EV +D + K+N +L GL IR C D K ++ + ++D
Sbjct: 177 EVTHVDASKKAIGWAKENQVLAGLEQAPIRWICEDAMKFIQREERR---------GSTYD 227
Query: 319 RILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356
IL D P G G + + + R++ +
Sbjct: 228 IILTDPPKFGRGTHGEVW--QLFDHLPLMLDICREILS 263
>6ELZ-w nrPDB
Length = 841
Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats.
Identities = 39/216 (18%), Positives = 73/216 (33%), Gaps = 31/216 (14%)
Query: 238 ILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKA 297
++DLCAAPG + L +I +D + K + ++ F D T
Sbjct: 50 VIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMK-----------PMPNVITFQSDITTE 98
Query: 298 VKLDMVEDTEGEPPFLPESFDRILLD-APCSGMGQRPNMACTWSVKEVASYQPLQRKLFT 356
+ D +L D AP G+G W Q + L
Sbjct: 99 DCRSKLRGYMKTW-----KADTVLHDGAPNVGLG--------WVQDAFTQSQLTLQALKL 145
Query: 357 AAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCE 416
A L+ G V I +++ ++ W + +++ +P + C+
Sbjct: 146 AVENLVVN-GTFVT---KIFRSKDYNKLIWVFQQLFE-KVEATKPPASRNVSAEIFVVCK 200
Query: 417 QLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLAN 452
K +R DP + P + L + ++ ++ N
Sbjct: 201 GFKAPKRLDPRLLD-PKEVFEELPDGQQNMESKIYN 235
>3C3Y-A nrPDB
Length = 237
Score = 31.4 bits (69), Expect = 1.00, Method: Composition-based stats.
Identities = 34/197 (17%), Positives = 64/197 (32%), Gaps = 36/197 (18%)
Query: 215 YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEK 274
Y+ L L+S VL +K +++ G A + D G++ A+D E
Sbjct: 51 YMSTSPLAGQLMSFVLKLVNAKKTIEVGVFTGYSLLLTALSIPDDGKITAIDFDREAYEI 110
Query: 275 IKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPN 334
G+ F ++++ E E S+D +DA +PN
Sbjct: 111 GLPFIRKAGVEHKINFIESDAMLALDNLLQGQESE-----GSYDFGFVDA------DKPN 159
Query: 335 MACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTC----TITLAENEEQVAWALTK 390
++L+K G++ Y T+ E+E +
Sbjct: 160 YIKYH----------------ERLMKLVKVGGIVAYDNTLWGGTVAQPESE-VPDFMKEN 202
Query: 391 FPCL----QLQPQEPQI 403
+ +L +P+I
Sbjct: 203 REAVIELNKLLAADPRI 219
>2PBF-A nrPDB
Length = 227
Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats.
Identities = 29/156 (18%), Positives = 59/156 (37%), Gaps = 15/156 (9%)
Query: 233 QPGEKILDLCAAPGGKTTHIAALM----HDQGEVIALDKIFNKVEKIKQNALLLGLNSIR 288
+PG + +D+ + G T +A M + VI L+++ + V +N
Sbjct: 79 KPGSRAIDVGSGSGYLTVCMAIKMNVLENKNSYVIGLERVKDLVNFSLENIKRDKPE--- 135
Query: 289 AFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQ 348
D K + ++ + E E L FD I + A S + P + +
Sbjct: 136 LLKIDNFKIIHKNIYQVNEEEKKELG-LFDAIHVGASAS---ELPEILVDLLAENGKLII 191
Query: 349 PLQRKLFTAAVQLLKPEGVLV----YSTCTITLAEN 380
P++ ++ K G ++ + C ++L +N
Sbjct: 192 PIEEDYTQVLYEITKKNGKIIKDRLFDVCFVSLKKN 227
>2J28-9 nrPDB
Length = 430
Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats.
Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 4/74 (5%)
Query: 138 ASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIR 197
AS+ + GDV+S+ DI+ K + E +K+ G+G E + + GM
Sbjct: 290 ASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDFLEQLRQMKNMGGMASL 349
Query: 198 MTEPVYLSPSFDSV 211
M P +
Sbjct: 350 M----GKLPGMGQI 359
>3BKX-A nrPDB
Length = 275
Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats.
Identities = 18/104 (17%), Positives = 34/104 (32%), Gaps = 3/104 (2%)
Query: 219 QNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQN 278
Q ++ +PGEKIL++ G + +A + G V +D
Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTL 87
Query: 279 ALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILL 322
T ++ ++ P + FDR++L
Sbjct: 88 GQAWNHLLAGPLGDRLTVHFNTNL---SDDLGPIADQHFDRVVL 128
>5VM2-A nrPDB
Length = 347
Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats.
Identities = 15/75 (20%), Positives = 28/75 (37%)
Query: 203 YLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEV 262
Y P + L + + + +PG+KI+ L A G T A E+
Sbjct: 137 YKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEI 196
Query: 263 IALDKIFNKVEKIKQ 277
+D + ++ +Q
Sbjct: 197 AVVDVLEKRLAMAEQ 211
>5LLK-A nrPDB
Length = 266
Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 6/109 (5%)
Query: 205 SPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIA 264
P SV ++ ++ H +P PGE + CAA T L D ++
Sbjct: 96 IPQTSSVFSIEVYPEDHSELQSVHTASPDPGEVVSSACAADEPVTVLTVILDADLTKMTP 155
Query: 265 LDKI--FNKVEKIKQ----NALLLGLNSIRAFCFDGTKAVKLDMVEDTE 307
+I +++ + N L+ + + R F A + + E
Sbjct: 156 KQRIDLLHRMRSFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVE 204
>2GNO-A nrPDB
Length = 305
Score = 30.2 bits (66), Expect = 1.8, Method: Composition-based stats.
Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 15 NYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNT-----HLASVQHVKN 69
NY E + K ++ ++ ++ LK L PP + + +NT L +++
Sbjct: 75 NYSPELYTRKYVIVHDCERMTQQAANAFLKALEEPPEYAVIVLNTRRWHYLLPTIKSRVF 134
Query: 70 LLLDELQKQFNGL 82
++ + K+F L
Sbjct: 135 RVVVNVPKEFRDL 147
>2HZ7-A nrPDB
Length = 851
Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats.
Identities = 34/195 (17%), Positives = 66/195 (33%), Gaps = 9/195 (4%)
Query: 253 AALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPF 312
A + QG+ ++ +++ NA G + D + LD++ +
Sbjct: 150 AEQLIRQGDAYVESVSPEELSRLRGNATTPG---TPSPYRDRSVEENLDLLRRMKAGEFA 206
Query: 313 LPESFDRILLD--APCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVY 370
E R +D AP + + P + + + L+ V
Sbjct: 207 DGEHVLRAKIDLTAP-NMKLRDPVLYRIVNKPHFRTSDEWHIYPAYDFEHPLQDAIEGVT 265
Query: 371 -STCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAV 429
S C++ +N W + K +P + + G G+ S +L++L +
Sbjct: 266 HSMCSLEFVDNRAIYDWLMEKL-NFDPRPHQYEFGRRGLEYTITSKRKLRELVQ-AGRVS 323
Query: 430 PLPDTDMDSLREARR 444
D M +LR RR
Sbjct: 324 GWDDPRMPTLRAQRR 338
>1ULZ-A nrPDB
Length = 451
Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats.
Identities = 22/122 (18%), Positives = 39/122 (31%), Gaps = 23/122 (18%)
Query: 1 MSIFPKISLRPEVENYLKE---------GFMNKEIVTALGKQEAERKFETLLKHLS--HP 49
+ I P + L PE Y G+ N + + QE F + + HP
Sbjct: 238 VEIAPSLILTPEKREYYGNIVTKAAKEIGYYNAGTMEFIADQEGNLYFIEMNTRIQVEHP 297
Query: 50 PSFTTVRVNTHL--ASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNI 107
S ++ + + L + + +FNG ++ I P+KN
Sbjct: 298 VSEMVTGIDIVKWQIKIAAGEPLTIKQEDVKFNGYAIEC----------RINAEDPKKNF 347
Query: 108 KK 109
Sbjct: 348 AP 349
>1P6U-A nrPDB
Length = 129
Score = 30.2 bits (66), Expect = 2.0, Method: Composition-based stats.
Identities = 21/112 (18%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 168 TKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYL------SPSFDSVLPRYLFLQNL 221
+++ LG+ + +L K+I + +GM I P +L P D + N
Sbjct: 18 SRLLLGDALQQLGFKQITAAGDGEQGMKIMAQNPHHLVISDFNMPKMDGLGLLQAVRANP 77
Query: 222 PSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVE 273
+ + ++ G++ L AA G +A + A++ +F ++
Sbjct: 78 ATKKAAFIILTAQGDRALVQKAAALGANNVLAKPFTIEKMKAAIEAVFGALK 129
>5WP5-A nrPDB
Length = 491
Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats.
Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 230 LNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNA 279
++ +PG+K+LD+ GG ++A V+ +D N + + A
Sbjct: 278 MDLKPGQKVLDVGCGIGGGDFYMAENF--DVHVVGIDLSVNMISFALERA 325
>2EQA-A nrPDB
Length = 352
Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 5 PKISLRP---EVENYLKEGFMNKEIVT-ALGKQEAERKFETLLKHLSHPPSFTTVRVN-- 58
P + LRP +E LK+ F I A GK+EAE +K+ + P+ + V
Sbjct: 191 PPVLLRPGPFTIEE-LKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPNTRLLLVENR 249
Query: 59 -------THLASVQHVKNLLLDELQKQFNGLSVPILQH 89
+ L+ V L+ EL K+F GL IL
Sbjct: 250 NIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGS 287
>2GKS-A nrPDB
Length = 546
Score = 29.1 bits (63), Expect = 3.9, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 5 PKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSH--------------PP 50
P S R +V N ++EG + V A + ER + L K PP
Sbjct: 454 PYRSARNQVRNMMEEGKFIEVFVDAPVEVCEERDVKGLYKKAKEGLIKGFTGVDDPYEPP 513
Query: 51 SFTTVRVNTHLASVQHVKNLLLDELQKQ 78
VRV+T + + +L+ L+K+
Sbjct: 514 VAPEVRVDTTKLTPEESALKILEFLKKE 541
>3ZV0-C nrPDB
Length = 195
Score = 29.1 bits (63), Expect = 4.3, Method: Composition-based stats.
Identities = 15/65 (23%), Positives = 27/65 (41%)
Query: 84 VPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMK 143
+P P +D+ GP + + +V NAV GA + PG++ + ++
Sbjct: 48 IPAGSSPLKRDLKSYISSGPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIE 107
Query: 144 AGDVI 148
D I
Sbjct: 108 LYDEI 112
>5O9X-A nrPDB
Length = 549
Score = 28.7 bits (62), Expect = 6.0, Method: Composition-based stats.
Identities = 25/109 (22%), Positives = 42/109 (38%), Gaps = 6/109 (5%)
Query: 157 KCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYL 216
+ +G K V NG+ +E+ LPE G+ I++ ++P +
Sbjct: 201 RVMRGVKVKGSLTVDCANGVGGPKLRELIKYLPEDTGLDIKIVNDDVINPDSLNFECGAD 260
Query: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIAL 265
+++ A S + ILD CA+ G I D+G V L
Sbjct: 261 YVKTKQRAPPSSKAS------ILDRCASLDGDADRILYYFLDEGNVFRL 303
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.307 0.118 0.302
Lambda K H
0.267 0.0354 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,289,028
Number of Sequences: 36641
Number of extensions: 574359
Number of successful extensions: 1889
Number of sequences better than 10.0: 76
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 1742
Number of HSP's gapped (non-prelim): 122
length of query: 469
length of database: 10,336,785
effective HSP length: 101
effective length of query: 368
effective length of database: 6,636,044
effective search space: 2442064192
effective search space used: 2442064192
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 60 (27.9 bits)