BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8TDY4 (903 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3LVQ-E nrPDB 595 e-170 2B0O-E nrPDB 592 e-169 1DCQ-A nrPDB 308 5e-84 5C6R-A nrPDB 191 1e-48 2DA0-A nrPDB 160 3e-39 3T9K-A nrPDB 120 3e-27 3FM8-C nrPDB 82 8e-16 2CRR-A nrPDB 82 9e-16 2IQJ-A nrPDB 73 6e-13 3O47-A nrPDB 73 7e-13 3DWD-A nrPDB 72 8e-13 5NZS-P nrPDB 67 3e-11 3SUB-A nrPDB 67 5e-11 2P57-A nrPDB 65 9e-11 2OWA-A nrPDB 63 6e-10 2CRW-A nrPDB 62 9e-10 6BY9-A nrPDB 50 4e-06 5AQA-A nrPDB 49 1e-05 6AUN-A nrPDB 47 3e-05 5AQ9-A nrPDB 47 5e-05 3B7B-A nrPDB 46 6e-05 5H76-A nrPDB 45 2e-04 5AQB-A nrPDB 44 3e-04 5CBO-A nrPDB 44 3e-04 5AQ7-A nrPDB 44 4e-04 5MIO-C nrPDB 41 0.003 2OLM-A nrPDB 40 0.004 6MWQ-A nrPDB 40 0.005 2D9L-A nrPDB 39 0.007 6FES-A nrPDB 39 0.008 3UI2-A nrPDB 39 0.012 3EU9-A nrPDB 39 0.015 3DEO-A nrPDB 38 0.022 5DND-A nrPDB 38 0.024 4H6Y-A nrPDB 35 0.098 5GP7-A nrPDB 35 0.10 4Z68-A nrPDB 34 0.34 5HKP-A nrPDB 33 0.59 5JHQ-A nrPDB 33 0.64 4NIK-A nrPDB 32 0.85 2DWZ-A nrPDB 32 1.1 2KXP-C nrPDB 32 1.3 4G9Y-A nrPDB 31 2.0 1V5U-A nrPDB 31 2.5 3ZKJ-A nrPDB 31 2.7 2DDM-A nrPDB 30 3.8 4OT9-A nrPDB 30 4.5 1G3N-B nrPDB 30 5.0 6E2G-A nrPDB 30 5.8 4CIU-A nrPDB 29 8.2 6OO7-A nrPDB 29 8.5 5AN8-A nrPDB 29 8.8 5ET1-A nrPDB 29 9.4 >3LVQ-E nrPDB Length = 497 Score = 595 bits (1535), Expect = e-170, Method: Compositional matrix adjust. Identities = 282/282 (100%), Positives = 282/282 (100%) Query: 416 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF 475 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF Sbjct: 1 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF 60 Query: 476 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKY 535 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKY Sbjct: 61 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKY 120 Query: 536 VEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVK 595 VEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVK Sbjct: 121 VEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVK 180 Query: 596 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAG 655 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAG Sbjct: 181 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAG 240 Query: 656 ETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 697 ETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE Sbjct: 241 ETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 282 >2B0O-E nrPDB Length = 301 Score = 592 bits (1525), Expect = e-169, Method: Compositional matrix adjust. Identities = 282/283 (99%), Positives = 283/283 (100%) Query: 415 AGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR 474 +GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR Sbjct: 19 SGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR 78 Query: 475 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAK 534 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAK Sbjct: 79 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAK 138 Query: 535 YVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAV 594 YVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAV Sbjct: 139 YVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAV 198 Query: 595 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 654 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA Sbjct: 199 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 258 Query: 655 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 697 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE Sbjct: 259 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 301 >1DCQ-A nrPDB Length = 278 Score = 308 bits (790), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 146/274 (53%), Positives = 194/274 (70%), Gaps = 4/274 (1%) Query: 423 DLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLT 482 +LTK +I+EV+ GN CCDCGA DPTWLSTNLG+LTCI+CSG+HRELGV +SRMQSLT Sbjct: 2 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT 61 Query: 483 LDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR 542 LD+LG SELLLA N+GN FNE+ME LPS KP+ SDM R+DYI AKY+E R+AR Sbjct: 62 LDVLGTSELLLAKNIGNAGFNEIMECCLPSEDPVKPNPGSDMIARKDYITAKYMERRYAR 121 Query: 543 R----CTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVAN 598 + + L A+ RD+ +L+A+A+G D + +P + P+E LHLAV+ + Sbjct: 122 KKHADTAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD 181 Query: 599 QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETA 658 + SL +VDF++QN G+LD + G+TALHY L + +CLKLLL+G+A + NE+GET Sbjct: 182 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP 241 Query: 659 LDIARKKHHKECEELLEQAQAGTFAFPLHVDYSW 692 LDIA++ H+ CEELL QA +G F +HV+Y W Sbjct: 242 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEW 275 >5C6R-A nrPDB Length = 150 Score = 191 bits (485), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 86/123 (69%), Positives = 101/123 (82%) Query: 289 GYSIHQHQGNKQFGTEKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKLTL 348 GYS+HQ QGNK++G+EK GFL KKSDGIR+VWQ+RKC VK G LTISH+T NR P KL L Sbjct: 25 GYSMHQLQGNKEYGSEKKGFLLKKSDGIRKVWQRRKCAVKNGILTISHATSNRQPAKLNL 84 Query: 349 LTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAG 408 LTCQV+PN E+KK FDL++HNRTYHFQAEDE + AW+SVL NSK+EAL+ AF GE S G Sbjct: 85 LTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNSKEEALTMAFRGEQSTG 144 Query: 409 PGS 411 S Sbjct: 145 ENS 147 >2DA0-A nrPDB Length = 114 Score = 160 bits (405), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 74/105 (70%), Positives = 87/105 (82%), Gaps = 1/105 (0%) Query: 304 EKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKLTLLTCQVRPNPEEKKCF 363 EK G+L KKSDGIR+VWQ+RKC VK G LTISH+T NR P KL LLTCQV+PN E+KK F Sbjct: 11 EKKGYLLKKSDGIRKVWQRRKCSVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSF 70 Query: 364 DLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAG 408 DL++HNRTYHFQAEDE + AW+SVL NSK+EAL+ AF G PS+G Sbjct: 71 DLISHNRTYHFQAEDEQDYVAWISVLTNSKEEALTMAFSG-PSSG 114 >3T9K-A nrPDB Length = 390 Score = 120 bits (300), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 95/328 (28%), Positives = 142/328 (43%), Gaps = 64/328 (19%) Query: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLG 487 ++A+V+S GN+QCCDC P W S NLGV CIQCSG+HR LGV FS+++SLTLD Sbjct: 35 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 94 Query: 488 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR----- 542 P + L +GN N++ EA++ + KP + +I AKYVE +F Sbjct: 95 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEI 154 Query: 543 -----------------------------RCTPEP--QRLWT----AICNR------DLL 561 R PEP + L + A+ R L Sbjct: 155 RGRRGGRGRPRGQPPVPPKPSIRPRPGDLRSKPEPPSEDLGSLHPGALLFRASGHPPSLP 214 Query: 562 SVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD 621 ++ +A A+G D G D P ++ SL +F++QNG +++ + Sbjct: 215 TMADALAHGADVNWVNGGQDNATP-------LIQATAANSLLACEFLLQNGANVNQADSA 267 Query: 622 GNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE------ 675 G LH+A + L LK A +G + G L IA + + + LL Sbjct: 268 GRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMRE 327 Query: 676 ----QAQAGTFAF-PLHVDYSWVISTEP 698 Q QAG + + D+S + S +P Sbjct: 328 AEAAQGQAGDETYLDIFRDFSLMASDDP 355 >3FM8-C nrPDB Length = 392 Score = 82.4 bits (202), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 49/149 (32%), Positives = 76/149 (51%), Gaps = 10/149 (6%) Query: 429 IAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGP 488 + E+ RPGN++C DCGA DP W S LGV C+ CSG+HR + + S+++S+ LD Sbjct: 27 VLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIP-QVSKVKSVRLDAWEE 85 Query: 489 SELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEP 548 +++ + GN + E+++PS +P+ R +I AKY F PE Sbjct: 86 AQVEFMASHGNDAARARFESKVPSFYY-RPTPSDCQLLREQWIRAKYERQEF---IYPEK 141 Query: 549 QRLWTAICNRDLLSVLEAFANGQDFGQPL 577 Q ++A L + G+D GQ L Sbjct: 142 QEPYSAGYREGFL-----WKRGRDNGQFL 165 >2CRR-A nrPDB Length = 141 Score = 82.0 bits (201), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 39/104 (37%), Positives = 61/104 (58%) Query: 410 GSWGSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHR 469 GS GS+G + ++ +L+++++ N C DC A P W S N+GV CI+C+G+HR Sbjct: 1 GSSGSSGKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHR 60 Query: 470 ELGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSH 513 LGV SR++S+ LD ++ +MGNT + EA LP + Sbjct: 61 NLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPEN 104 >2IQJ-A nrPDB Length = 134 Score = 72.8 bits (177), Expect = 6e-13, Method: Composition-based stats. Identities = 34/89 (38%), Positives = 49/89 (55%) Query: 423 DLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLT 482 D + ++A + N C DC + P W S N+GV CI+C+G+HR LGV SR++S+ Sbjct: 12 DRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 71 Query: 483 LDLLGPSELLLALNMGNTSFNEVMEAQLP 511 LD ++ MGN N + EA LP Sbjct: 72 LDQWTQEQIQCMQEMGNGKANRLYEAYLP 100 >3O47-A nrPDB Length = 329 Score = 72.8 bits (177), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 33/85 (38%), Positives = 51/85 (60%) Query: 425 TKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484 T+ ++ EV+ + N+ C +CGA +P W+S G+ C++CSG HR LGV S ++S+T+D Sbjct: 24 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 83 Query: 485 LLGPSELLLALNMGNTSFNEVMEAQ 509 EL GN F E +E+Q Sbjct: 84 KWKDIELEKMKAGGNAKFREFLESQ 108 >3DWD-A nrPDB Length = 147 Score = 72.4 bits (176), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 33/85 (38%), Positives = 51/85 (60%) Query: 425 TKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484 T+ ++ EV+ + N+ C +CGA +P W+S G+ C++CSG HR LGV S ++S+T+D Sbjct: 25 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 84 Query: 485 LLGPSELLLALNMGNTSFNEVMEAQ 509 EL GN F E +E+Q Sbjct: 85 KWKDIELEKMKAGGNAKFREFLESQ 109 >5NZS-P nrPDB Length = 520 Score = 67.4 bits (163), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 28/59 (47%), Positives = 35/59 (59%) Query: 426 KLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484 + L +++ P N C DCGA P+W S GV CI CSGVHR LGV S ++S LD Sbjct: 11 QTLFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69 >3SUB-A nrPDB Length = 163 Score = 66.6 bits (161), Expect = 5e-11, Method: Composition-based stats. Identities = 29/75 (38%), Positives = 42/75 (56%) Query: 433 KSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELL 492 K N++C DCG ++P W+S N G+ CI CSGVHR LGV S ++S+ +D+ +L Sbjct: 17 KEDESNNKCFDCGISNPDWVSVNHGIFLCINCSGVHRSLGVHISIVRSIKMDIFTDEQLK 76 Query: 493 LALNMGNTSFNEVME 507 GN +E Sbjct: 77 YIDKGGNKKCQTYLE 91 >2P57-A nrPDB Length = 144 Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLG 487 L +++ P N C DCGA +P+W S GV CI CSGVHR LGV S ++S LD Sbjct: 27 LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNW 86 Query: 488 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTR 527 L + +G N A HG A + +R Sbjct: 87 NWFQLRCMQVGG---NANATAFFRQHGCTANDANTKYNSR 123 >2OWA-A nrPDB Length = 138 Score = 63.2 bits (152), Expect = 6e-10, Method: Composition-based stats. Identities = 26/61 (42%), Positives = 38/61 (62%) Query: 432 VKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSEL 491 V++RP N C DC + +PTWLS + V C+ CS HR++GV S ++S LD P +L Sbjct: 30 VRNRPENRTCFDCESRNPTWLSLSFAVFICLNCSSDHRKMGVHISFVRSSDLDKFTPIQL 89 Query: 492 L 492 + Sbjct: 90 V 90 >2CRW-A nrPDB Length = 149 Score = 62.4 bits (150), Expect = 9e-10, Method: Composition-based stats. Identities = 27/57 (47%), Positives = 34/57 (59%) Query: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484 + ++S P N C DCGA +P+W S GV CI CSG HR LGV S ++S LD Sbjct: 19 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 75 >6BY9-A nrPDB Length = 328 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 58/217 (26%), Positives = 90/217 (41%), Gaps = 30/217 (13%) Query: 548 PQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDF 607 P++L+ + +L VL +G D + + ++P LH A A + + Sbjct: 68 PKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSP----LHAA---AEAGHVDICHM 120 Query: 608 IIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHH 667 ++Q G ++D + D T L AA N + +K L+K ALV + G T L +A KK H Sbjct: 121 LVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGH 180 Query: 668 KE-CEELLEQAQAGTFA------FPL-------HVDYSWVISTEPGSDSEEDEEEKRCLL 713 E + LL Q P+ HVD ++ ++ + D EE CL Sbjct: 181 YEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICL- 239 Query: 714 KLPAQAHWA--SGRLDISNKTYETVASLGAATPQGES 748 HWA SG +DI+ L A G+S Sbjct: 240 ------HWAAFSGCVDIAEILLAAKCDLHAVNIHGDS 270 >5AQA-A nrPDB Length = 418 Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ ++++G +DA G T LH AA + + +++LLK A V Sbjct: 51 LHLA---AYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVN 107 Query: 650 TVNEAGETALDIARKKHHKECEELLEQAQA 679 ++ G T L +A K +KE E+L +A A Sbjct: 108 AMDSDGMTPLHLAAKWGYKEIVEVLLKAGA 137 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 3/89 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ +++NG ++A +DG T LH AA + + +++LLK A V Sbjct: 84 LHLA---AYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVD 140 Query: 650 TVNEAGETALDIARKKHHKECEELLEQAQ 678 ++ G+ L +A + H E L A+ Sbjct: 141 AQDKFGKRPLWLAADQGHAEIAAKLVAAR 169 >6AUN-A nrPDB Length = 752 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 25/63 (39%), Positives = 37/63 (58%) Query: 607 FIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKH 666 +++ G +D+ +A GNTALH A + N+ DC+ +LL A GT E G T L +A K Sbjct: 302 MLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKD 361 Query: 667 HKE 669 + E Sbjct: 362 NME 364 Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust. Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 8/104 (7%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK-GRALV 648 LHLA + + S LV+ + +D G TA HYA + L+LL K A + Sbjct: 156 LHLACRKGD--SEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGL 213 Query: 649 GTVNEAGETALDIARKKHHKECEELLEQAQA-----GTFAFPLH 687 VN+ G T L +A + +E +L A G FP+H Sbjct: 214 NQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIH 257 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 4/97 (4%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LH+AV + N+ +V ++ G + GNT LH A + + +K L+ A V Sbjct: 321 LHVAV-MRNRFDCVMV--LLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVD 377 Query: 650 TVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPL 686 T N+ GET +A K K+ ++L+ ++A AF L Sbjct: 378 TPNDFGETPAFMASKI-SKQLQDLMPISRARKPAFIL 413 >5AQ9-A nrPDB Length = 422 Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ +++NG ++A +DG T LH AA + + +++LLK A V Sbjct: 84 LHLA---AYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVN 140 Query: 650 TVNEAGETALDIARKKHHKECEELLEQAQA 679 ++ G+T D+A + + LL+ A A Sbjct: 141 AQDKFGKTPFDLADDNGNDDVGTLLQVAAA 170 Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 3/85 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ ++++G +DA G T LH AA + + +++LLK A V Sbjct: 51 LHLA---AYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVN 107 Query: 650 TVNEAGETALDIARKKHHKECEELL 674 ++ G T L +A K + E E+L Sbjct: 108 AMDSDGMTPLHLAAKWGYLEIVEVL 132 >3B7B-A nrPDB Length = 237 Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 62/227 (27%), Positives = 92/227 (40%), Gaps = 34/227 (14%) Query: 597 ANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGE 656 A + + ++Q G ++D + D T L AA N + +K L+K ALV + G Sbjct: 19 AEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGS 78 Query: 657 TALDIARKKHHKE-CEELLEQAQAGTFA------FPL-------HVDYSWVISTEPGSDS 702 T L +A KK H E + LL Q P+ HVD ++ ++ + Sbjct: 79 TCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDIN 138 Query: 703 EEDEEEKRCLLKLPAQAHWA--SGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNS 760 D EE CL HWA SG +DI+ L A G+S P+ + Sbjct: 139 IRDNEENICL-------HWAAFSGCVDIAEILLAAKCDLHAVNIHGDS-------PLHIA 184 Query: 761 SRTLVQGCARHASGDRSEVSSLSSEAPETP---ESLGSPASSSSLMS 804 +R C S+V +L ++ ETP SL S S+ MS Sbjct: 185 ARENRYDCVVLFLSRDSDV-TLKNKEGETPLQCASLNSQVWSALQMS 230 >5H76-A nrPDB Length = 201 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 10/107 (9%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ ++++G +DA G T LH AA + + +++LLK A V Sbjct: 43 LHLA---AYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVN 99 Query: 650 TVNEAGETALDIARKKHHKECEELL-------EQAQAGTFAFPLHVD 689 ++ G T L +A K + E E+L Q + G AF + +D Sbjct: 100 AMDSDGMTPLHLAAKWGYLEIVEVLLKHGAVNAQDKFGKTAFDISID 146 >5AQB-A nrPDB Length = 428 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 7/99 (7%) Query: 579 GPDAQAPEELV---LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQP 635 G D A +E+ LHLA L +V+ +++NG ++A DG T LH AA Sbjct: 37 GADVNALDEVGWTPLHLAA----WGHLEIVECLLKNGADVNAADIDGYTPLHLAAFSGHL 92 Query: 636 DCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELL 674 + +++LLK A V ++AG T L +A H E E+L Sbjct: 93 EIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVL 131 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 3/88 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ +++ G ++A G T LH AA++ + +++LLK A V Sbjct: 83 LHLA---AFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVN 139 Query: 650 TVNEAGETALDIARKKHHKECEELLEQA 677 ++ G+T D+A +++ E+L +A Sbjct: 140 AQDKFGKTPRDLAIDNGNEDIAEVLGKA 167 >5CBO-A nrPDB Length = 176 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 5/101 (4%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A +V+ +++ G ++A A G+T LH AA + +++LLK A V Sbjct: 40 LHLA---AYWGHFEIVEVLLKYGADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADVN 96 Query: 650 TVNEAGETALDIARKKHHKECEELL--EQAQAGTFAFPLHV 688 ++ G+TA DI+ +++ E+L +AQ F LH+ Sbjct: 97 AQDKFGKTAFDISIDNGNEDLAEILCKNKAQQAAFYCILHM 137 >5AQ7-A nrPDB Length = 418 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A + L +V+ +++NG ++A G+T LH AA + +++LLK A V Sbjct: 51 LHLA---AWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVN 107 Query: 650 TVNEAGETALDIARKKHHKECEELLEQAQA 679 + G L +A +KE E+L +A A Sbjct: 108 ATDVIGTAPLHLAAMWGYKEIVEVLLKAGA 137 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 13/129 (10%) Query: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 664 V ++ NG ++ G T LH AA +++LLK A V +E G T L +A Sbjct: 30 VRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAY 89 Query: 665 KHHKECEELLEQAQAGTFAF------PLHVDYSW------VISTEPGSDSE-EDEEEKRC 711 H E E+L + AG A PLH+ W + + G+D + +D+ KR Sbjct: 90 TGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRP 149 Query: 712 LLKLPAQAH 720 L Q H Sbjct: 150 LWLAADQGH 158 Score = 39.7 bits (91), Expect = 0.006, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 6/103 (5%) Query: 579 GPDAQAPEE---LVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQP 635 G D A +E LHLA A L +V+ +++NG ++A G LH AA++ Sbjct: 70 GADVNANDERGHTPLHLA---AYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYK 126 Query: 636 DCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 + +++LLK A V ++ G+ L +A + H E L A+ Sbjct: 127 EIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAAR 169 >5MIO-C nrPDB Length = 573 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 11/108 (10%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ ++++G + A G+T LH AAL + +++LLK A V Sbjct: 447 LHLA---ATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVN 503 Query: 650 TVNEAGETALDIARKKHH-KECEELLE-------QAQAGTFAFPLHVD 689 V+ G+T L +A H K E LL+ Q + G A+ +D Sbjct: 504 AVDTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSID 551 Score = 37.7 bits (86), Expect = 0.023, Method: Compositional matrix adjust. Identities = 25/70 (35%), Positives = 36/70 (51%) Query: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 664 V ++ NG ++A A G T LH AA Y + +++LLK A V + G T L +A Sbjct: 426 VRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAAL 485 Query: 665 KHHKECEELL 674 H E E+L Sbjct: 486 IGHLEIVEVL 495 Score = 34.7 bits (78), Expect = 0.20, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA + + L +V+ ++++G ++A G+T L AA+ ++ LLK A V Sbjct: 480 LHLAALIGH---LEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVN 536 Query: 650 TVNEAGETALDIARKKHHKECEELLEQ 676 ++ G+TA D + ++ E+L++ Sbjct: 537 AQDKFGKTAYDTSIDNGSEDLAEILQK 563 >2OLM-A nrPDB Length = 140 Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/113 (21%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLG 487 ++ ++ P N +C DC PT+++ +G C CSG R L R++S+++ Sbjct: 15 MLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTFT 73 Query: 488 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRF 540 E+ GN ++ P D ++++ KY + R+ Sbjct: 74 QQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFR-DPQKVKEFLQEKYEKKRW 125 >6MWQ-A nrPDB Length = 493 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A L +V+ +++ G ++A G T LH A+ + +++LLK A V Sbjct: 75 LHLA---ATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGADVN 131 Query: 650 TVNEAGETALDIARKKHHKECEELLEQ 676 ++ G+TA DI+ +++ E+L++ Sbjct: 132 AQDKFGKTAFDISIDNGNEDLAEILQK 158 Score = 38.9 bits (89), Expect = 0.011, Method: Compositional matrix adjust. Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A + L +V+ +++ G ++A G T LH AA + +++LLK A V Sbjct: 42 LHLA---AQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVN 98 Query: 650 TVNEAGETALDIARKKHHKECEELL--------EQAQAGTFAFPLHVD 689 ++ G+T L + H E E+L Q + G AF + +D Sbjct: 99 ALDLIGKTPLHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISID 146 >2D9L-A nrPDB Length = 134 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 24/113 (21%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLG 487 ++ ++ P N +C DC PT+++ +G C CSG R L R++S+++ Sbjct: 10 MLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTFT 68 Query: 488 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRF 540 E+ GN ++ P D ++++ KY + R+ Sbjct: 69 QQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFR-DPQKVKEFLQEKYEKKRW 120 >6FES-A nrPDB Length = 367 Score = 39.3 bits (90), Expect = 0.008, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 3/85 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A + L +V+ +++NG ++A G+T LH AA + +++LLK A V Sbjct: 43 LHLA---AWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVN 99 Query: 650 TVNEAGETALDIARKKHHKECEELL 674 + G L +A H+E E+L Sbjct: 100 ATDVIGTAPLHLAAMWGHEEIVEVL 124 Score = 37.4 bits (85), Expect = 0.028, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 6/98 (6%) Query: 579 GPDAQAPEE---LVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQP 635 G D A +E LHLA A L +V+ +++NG ++A G LH AA++ Sbjct: 62 GADVNANDERGHTPLHLA---AYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHE 118 Query: 636 DCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEEL 673 + +++LLK A ++ G+T D+AR ++ L Sbjct: 119 EIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARL 156 Score = 37.4 bits (85), Expect = 0.030, Method: Compositional matrix adjust. Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%) Query: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 664 V ++ NG ++ G T LH AA +++LLK A V +E G T L +A Sbjct: 22 VRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAY 81 Query: 665 KHHKECEELLEQAQAGTFAF------PLHVDYSW 692 H E E+L + AG A PLH+ W Sbjct: 82 TGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMW 115 >3UI2-A nrPDB Length = 244 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 1/98 (1%) Query: 568 ANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGN-TAL 626 A+ Q Q L D A +E + VA S V + + G LD + G TAL Sbjct: 56 ADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTAL 115 Query: 627 HYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 664 H AA Y +P+ ++ L++ A + +E G TAL++AR+ Sbjct: 116 HMAAGYVRPEVVEALVELGADIEVEDERGLTALELARE 153 >3EU9-A nrPDB Length = 240 Score = 38.5 bits (88), Expect = 0.015, Method: Composition-based stats. Identities = 19/43 (44%), Positives = 27/43 (62%) Query: 623 NTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKK 665 NTALH+A L + LLL+ A V N GE+ALD+A+++ Sbjct: 178 NTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQR 220 >3DEO-A nrPDB Length = 183 Score = 37.7 bits (86), Expect = 0.022, Method: Compositional matrix adjust. Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 1/98 (1%) Query: 568 ANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGN-TAL 626 A+ Q Q L D A +E + VA S V + + G LD + G TAL Sbjct: 55 ADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTAL 114 Query: 627 HYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 664 H AA Y +P+ ++ L++ A + +E G TAL++AR+ Sbjct: 115 HMAAGYVRPEVVEALVELGADIEVEDERGLTALELARE 152 >5DND-A nrPDB Length = 588 Score = 37.7 bits (86), Expect = 0.024, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 44/88 (50%) Query: 592 LAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTV 651 LA+ +A+ L + +++ G L K ++G T LH AA + + +LL V Sbjct: 425 LALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNAR 484 Query: 652 NEAGETALDIARKKHHKECEELLEQAQA 679 + G + L +A + H+EC LL +A A Sbjct: 485 DRDGLSPLLLAVQGRHRECIRLLRKAGA 512 >4H6Y-A nrPDB Length = 501 Score = 35.4 bits (80), Expect = 0.098, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 310 YKKSDGIRRVWQ--KRKCGVKYGCLTISHSTINRPPVKLTLLTCQVRPNPEEKKCFDLVT 367 +K S+G +++W C Y +H + P + +L N ++ F L Sbjct: 409 FKNSNGWQKLWVVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHF 468 Query: 368 HNRTYHFQAEDEHECEAWVSVLQNSKDEA 396 + Y+F+AE E+ E W+ V++++ A Sbjct: 469 KSHVYYFRAESEYTFERWMEVIRSATSSA 497 >5GP7-A nrPDB Length = 169 Score = 35.4 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 4/95 (4%) Query: 581 DAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKL 640 D Q LHLA N L + ++++++G ++A+ G LH AA Y D L Sbjct: 38 DTQGRNSTPLHLAAGYNN---LEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAAL 94 Query: 641 LLKGRALVGTVNEAGETAL-DIARKKHHKECEELL 674 L+K V ++ T L + A+K + C LL Sbjct: 95 LIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLL 129 >4Z68-A nrPDB Length = 155 Score = 33.9 bits (76), Expect = 0.34, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 4/98 (4%) Query: 581 DAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKL 640 D + + LH A A + +V++++Q+G + AK G LH A Y + +L Sbjct: 32 DIEGRQSTPLHFA---AGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAEL 88 Query: 641 LLKGRALVGTVNEAGETAL-DIARKKHHKECEELLEQA 677 L+K A+V + T L + A K ++ C+ LL+ Sbjct: 89 LVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHG 126 >5HKP-A nrPDB Length = 351 Score = 33.1 bits (74), Expect = 0.59, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Query: 587 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRA 646 E LH AV + + + +++ G +++ K D T LH AA D +++L K A Sbjct: 212 ETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 271 Query: 647 LVGTVNEAGETALD-IARKKHHKECEELL 674 + ++ G+TAL A H + C LL Sbjct: 272 KMNALDSLGQTALHRAALAGHLQTCRLLL 300 Score = 30.4 bits (67), Expect = 3.8, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A + +V ++Q+G + AK G LH A Y + +LLLK A V Sbjct: 62 LHLA---AGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN 118 Query: 650 TVNEAGETALDIARKKHHKECEELL 674 ++ T L A K+ E LL Sbjct: 119 AMDLWQFTPLHEAASKNRVEVCSLL 143 Score = 29.3 bits (64), Expect = 7.3, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 615 LDAKAADG--NTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEE 672 ++ A+DG +T LH AA YN+ ++LLL+ A V ++ G L A H E E Sbjct: 49 VNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTE 108 Query: 673 LLEQAQAGTFAFPL 686 LL + A A L Sbjct: 109 LLLKHGACVNAMDL 122 >5JHQ-A nrPDB Length = 482 Score = 32.7 bits (73), Expect = 0.64, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 586 EELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGR 645 E LH AV + + + +++ G +++ K D T LH AA D +++L K Sbjct: 355 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 414 Query: 646 ALVGTVNEAGETALD-IARKKHHKECEELL 674 A + ++ G+TAL A H + C LL Sbjct: 415 AKMNALDTLGQTALHRAALAGHLQTCRLLL 444 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 LHLA A + +V ++Q+G + AK G LH A Y + +LLLK A V Sbjct: 206 LHLA---AGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN 262 Query: 650 TVNEAGETALDIARKKHHKECEELL 674 ++ T L A K+ E LL Sbjct: 263 AMDLWQFTPLHEAASKNRVEVCSLL 287 Score = 30.0 bits (66), Expect = 5.3, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 615 LDAKAADG--NTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEE 672 ++ A+DG +T LH AA YN+ ++LLL+ A V ++ G L A H E E Sbjct: 193 VNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTE 252 Query: 673 LLEQAQAGTFAFPL 686 LL + A A L Sbjct: 253 LLLKHGACVNAMDL 266 >4NIK-A nrPDB Length = 230 Score = 32.3 bits (72), Expect = 0.85, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 39/76 (51%) Query: 604 LVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIAR 663 +V+F++Q G ++ K G + LH AA + + +K LL A V VN+ G T L A Sbjct: 59 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 118 Query: 664 KKHHKECEELLEQAQA 679 K+ E +L + A Sbjct: 119 SKNRHEIAVMLLEGGA 134 >2DWZ-A nrPDB Length = 231 Score = 32.3 bits (72), Expect = 1.1, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 39/76 (51%) Query: 604 LVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIAR 663 +V+F++Q G ++ K G + LH AA + + +K LL A V VN+ G T L A Sbjct: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAA 114 Query: 664 KKHHKECEELLEQAQA 679 K+ E +L + A Sbjct: 115 SKNRHEIAVMLLEGGA 130 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 3/57 (5%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRA 646 LH+A A+ +V ++ G H++A +G T LHYAA N+ + +LL+G A Sbjct: 77 LHIA---ASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA 130 >2KXP-C nrPDB Length = 118 Score = 32.0 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 10/110 (9%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 +W A+ N DL V + A G+D + L G + P LH A A+ L +++F++ Sbjct: 7 MW-ALKNGDLDEVKDYVAKGEDVNRTLEG--GRKP----LHYA---ADCGQLEILEFLLL 56 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALD 660 G ++A T L A C+KLLL A G TAL+ Sbjct: 57 KGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALE 106 >4G9Y-A nrPDB Length = 157 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 40/131 (30%), Positives = 51/131 (38%), Gaps = 10/131 (7%) Query: 362 CFDLVTHNRTYHFQAEDEHEC--EAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDG 419 DL TH + + H VS S A+ +A + EP + G Sbjct: 6 AVDLATHPGHLARRLQQAHYLLWNTMVSEETTSPQYAVLNALVAEPGLDQRTVG------ 59 Query: 420 EPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQ 479 E L + IAEV SR G D DP +L LT + VHR LGVR +RM Sbjct: 60 ERVGLDRSTIAEVVSRLGRRGLLDK-VRDPQDGRRSLLRLTD-EGLRVHRRLGVRIARMN 117 Query: 480 SLTLDLLGPSE 490 + L L E Sbjct: 118 QVFLAPLAADE 128 >1V5U-A nrPDB Length = 117 Score = 30.8 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 22/43 (51%) Query: 358 EEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSA 400 +EK FD+ T R Y+F A+D + WV +Q+ SS Sbjct: 75 DEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSSGPSSG 117 >3ZKJ-A nrPDB Length = 261 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 5/85 (5%) Query: 608 IIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHH 667 +I G ++ AD + LH A L C+K+LLK A V V T L A Sbjct: 22 LISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGS 81 Query: 668 KECEELLEQAQAGT-----FAFPLH 687 +C LL Q A A P+H Sbjct: 82 WDCVNLLLQHGASVQPESDLASPIH 106 Score = 30.4 bits (67), Expect = 4.0, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 602 LPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDI 661 L V ++++G ++ AD +T L A + DC+ LLL+ A V ++ + Sbjct: 49 LSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEA 108 Query: 662 ARKKHHKEC 670 AR+ H EC Sbjct: 109 ARRG-HVEC 116 >2DDM-A nrPDB Length = 283 Score = 30.4 bits (67), Expect = 3.8, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 641 LLKGRALVGTVNEAGETALDIARKKHHKECEELL 674 LLKG+AL V+ AG L++ R E +EL+ Sbjct: 243 LLKGKALTDAVHRAGLRVLEVMRYTQQHESDELI 276 >4OT9-A nrPDB Length = 359 Score = 30.0 bits (66), Expect = 4.5, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 590 LHLAVKVANQASLPLVDFIIQN-GGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALV 648 LHLA ++ L LV ++ +++A+ GNT LH AA P +LLLK A + Sbjct: 232 LHLATEMEE---LGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI 288 Query: 649 GTVNE 653 NE Sbjct: 289 HAENE 293 Score = 29.3 bits (64), Expect = 7.7, Method: Compositional matrix adjust. Identities = 40/146 (27%), Positives = 60/146 (41%), Gaps = 20/146 (13%) Query: 590 LHLAVKVANQASLPLVDFIIQNGGH-----LDAKAADGNTALHYAALYNQPDCLKLLLKG 644 +HLA++ A + L+ ++Q+G L +G +H A P+CL LL+ Sbjct: 158 MHLALR-AGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDS 216 Query: 645 RALV-GTVNEAGETALDIARKKHH-----KECEELLEQAQAGTFA--FPLHVDYSWVIST 696 A V T + G TAL +A + +L A TFA PLH+ T Sbjct: 217 GAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPT 276 Query: 697 ------EPGSDSEEDEEEKRCLLKLP 716 + G+D + EE C L P Sbjct: 277 LTRLLLKAGADIHAENEEPLCPLPSP 302 >1G3N-B nrPDB Length = 168 Score = 30.0 bits (66), Expect = 5.0, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRAL-VGTVNEAGETALDIARKKHHKECEELLEQAQA 679 +GN LH AA ++ L+K A VG N G+TA D+AR E L++ A Sbjct: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 Query: 680 G 680 G Sbjct: 162 G 162 >6E2G-A nrPDB Length = 727 Score = 29.6 bits (65), Expect = 5.8, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 11/80 (13%) Query: 590 LHLAVKVAN-QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKG---- 644 L LA K N QA + L+ F G + K A G TALH AALY+ + +L++ Sbjct: 49 LLLAAKENNVQALIKLLKF---EGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 105 Query: 645 --RALVGTVNEAGETALDIA 662 + + E G+TAL IA Sbjct: 106 VFEPMTSELYE-GQTALHIA 124 >4CIU-A nrPDB Length = 727 Score = 29.3 bits (64), Expect = 8.2, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 185 ERRIFQLHM-CEYLLKAGESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKL 243 +RRI QL + + L+KA + K+ D L + Q++ ++ WKA ++ + + Sbjct: 274 DRRIIQLKLEQQALMKASDEASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTI 333 Query: 244 AASVH----ALHQAQE-------DELQ--KLTQLRDSLRGTLQLESREEHLSR 283 A + A+ QA+ ELQ K+ +L L QLE + L R Sbjct: 334 KAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLR 386 >6OO7-A nrPDB Length = 786 Score = 29.3 bits (64), Expect = 8.5, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 21/91 (23%) Query: 571 QDFGQPLPGPDAQAPEEL-----VLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD---- 621 +D G P P +AQ +E LH+A++ + SL V +++NG ++ AKA Sbjct: 142 RDSGNPQPLVNAQCTDEYYRGHSALHIAIE---KRSLQCVKLLVENGANVHAKACGHFFQ 198 Query: 622 ---------GNTALHYAALYNQPDCLKLLLK 643 G L AA Q D + LL+ Sbjct: 199 KNQDTCFYFGELPLSLAACTKQWDVVNYLLE 229 >5AN8-A nrPDB Length = 613 Score = 29.3 bits (64), Expect = 8.8, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 8/55 (14%) Query: 571 QDFGQPLPGPDAQAPEELV-----LHLAVKVANQASLPLVDFIIQNGGHLDAKAA 620 +D G P P +AQ +E LH+A++ + SL V +++NG ++ AKA Sbjct: 67 RDSGNPQPLVNAQCTDEYYRGHSALHIAIE---KRSLQCVKLLVENGANVHAKAC 118 >5ET1-A nrPDB Length = 353 Score = 28.9 bits (63), Expect = 9.4, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 25/57 (43%) Query: 622 GNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G T LH AA + +C ++L A + + G TA D+A H C L Q Sbjct: 273 GGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQ 329 Score = 28.9 bits (63), Expect = 9.8, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%) Query: 607 FIIQNGGHLDAKAADGNTALHYAALYNQPDCLK-LLLKGRALVGTVNEAGETALDIARKK 665 + Q G + K G T LH AA + PD +K LL +G A + G + A K Sbjct: 90 LLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAK 149 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2B0O-E nrPDB 441 e-124 3LVQ-E nrPDB 441 e-124 1DCQ-A nrPDB 370 e-102 3T9K-A nrPDB 306 4e-83 6BY9-A nrPDB 303 2e-82 3B7B-A nrPDB 270 2e-72 5C6R-A nrPDB 251 9e-67 2DA0-A nrPDB 210 2e-54 3FM8-C nrPDB 192 8e-49 2CRR-A nrPDB 168 9e-42 2IQJ-A nrPDB 157 1e-38 2P57-A nrPDB 149 6e-36 5AQ9-A nrPDB 144 1e-34 5AQA-A nrPDB 144 1e-34 3O47-A nrPDB 143 3e-34 5H76-A nrPDB 142 4e-34 5NZS-P nrPDB 141 2e-33 3DWD-A nrPDB 139 6e-33 5AQB-A nrPDB 138 1e-32 2CRW-A nrPDB 137 2e-32 5AQ7-A nrPDB 136 3e-32 5CBO-A nrPDB 135 9e-32 3SUB-A nrPDB 122 5e-28 2OWA-A nrPDB 121 2e-27 6AUN-A nrPDB 93 6e-19 Sequences not found previously or not previously below threshold: 6FES-A nrPDB 134 1e-31 6MWQ-A nrPDB 125 1e-28 5MIO-C nrPDB 119 6e-27 4NIK-A nrPDB 89 1e-17 5JHQ-A nrPDB 87 4e-17 2DWZ-A nrPDB 86 8e-17 4Z68-A nrPDB 84 2e-16 2OLM-A nrPDB 83 6e-16 2D9L-A nrPDB 82 1e-15 3EU9-A nrPDB 82 1e-15 5HKP-A nrPDB 81 2e-15 5GP7-A nrPDB 81 2e-15 3ZKJ-A nrPDB 77 3e-14 5DND-A nrPDB 76 7e-14 2KXP-C nrPDB 74 3e-13 1G3N-B nrPDB 71 2e-12 5ET1-A nrPDB 71 3e-12 1BLX-B nrPDB 71 3e-12 4OAU-C nrPDB 71 3e-12 1BD8-A nrPDB 68 2e-11 3UI2-A nrPDB 65 1e-10 3DEO-A nrPDB 65 1e-10 4O1O-A nrPDB 64 4e-10 4OT9-A nrPDB 61 2e-09 1D9S-A nrPDB 61 3e-09 6EMK-G nrPDB 59 6e-09 2A5E-A nrPDB 59 7e-09 3EHQ-A nrPDB 57 4e-08 5D68-A nrPDB 55 2e-07 5U0K-A nrPDB 54 3e-07 4BSZ-B nrPDB 52 2e-06 5UQE-A nrPDB 51 2e-06 6E2G-A nrPDB 51 2e-06 2RFA-A nrPDB 51 2e-06 5U0J-A nrPDB 51 3e-06 6DMR-A nrPDB 50 4e-06 1WG0-A nrPDB 50 6e-06 5C5B-A nrPDB 48 2e-05 2F37-A nrPDB 47 4e-05 6BOA-A nrPDB 46 6e-05 4N5Q-A nrPDB 45 1e-04 5AN8-A nrPDB 45 2e-04 6DVZ-A nrPDB 45 2e-04 3LJN-A nrPDB 45 2e-04 5IRX-A nrPDB 44 3e-04 6OO7-A nrPDB 44 3e-04 6CV9-A nrPDB 42 0.001 2NYJ-A nrPDB 42 0.002 6BO5-A nrPDB 41 0.002 5HI9-A nrPDB 41 0.002 6DJS-A nrPDB 41 0.003 6CUD-A nrPDB 41 0.003 2ETB-A nrPDB 40 0.004 4XD0-A nrPDB 37 0.025 3ODW-A nrPDB 36 0.058 6MHW-A nrPDB 36 0.074 5UIL-A nrPDB 35 0.14 6BBJ-A nrPDB 35 0.18 6C8G-A nrPDB 34 0.34 4H6Y-A nrPDB 34 0.35 3W9G-A nrPDB 34 0.37 6G1K-A nrPDB 33 0.52 4DX2-A nrPDB 33 0.64 4WPZ-A nrPDB 32 0.86 1WPI-A nrPDB 32 0.93 2DHJ-A nrPDB 32 1.3 3V2G-A nrPDB 31 2.1 2J59-M nrPDB 31 2.2 1MPH-A nrPDB 31 2.2 1U5K-A nrPDB 31 2.9 1RP4-A nrPDB 30 3.8 >2B0O-E nrPDB Length = 301 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 282/283 (99%), Positives = 283/283 (100%) Query: 415 AGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR 474 +GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR Sbjct: 19 SGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR 78 Query: 475 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAK 534 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAK Sbjct: 79 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAK 138 Query: 535 YVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAV 594 YVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAV Sbjct: 139 YVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAV 198 Query: 595 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 654 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA Sbjct: 199 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 258 Query: 655 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 697 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE Sbjct: 259 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 301 >3LVQ-E nrPDB Length = 497 Score = 441 bits (1133), Expect = e-124, Method: Composition-based stats. Identities = 282/282 (100%), Positives = 282/282 (100%) Query: 416 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF 475 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF Sbjct: 1 GHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRF 60 Query: 476 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKY 535 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKY Sbjct: 61 SRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKY 120 Query: 536 VEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVK 595 VEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVK Sbjct: 121 VEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVK 180 Query: 596 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAG 655 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAG Sbjct: 181 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAG 240 Query: 656 ETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 697 ETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE Sbjct: 241 ETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTE 282 >1DCQ-A nrPDB Length = 278 Score = 370 bits (950), Expect = e-102, Method: Composition-based stats. Identities = 146/277 (52%), Positives = 195/277 (70%), Gaps = 4/277 (1%) Query: 423 DLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLT 482 +LTK +I+EV+ GN CCDCGA DPTWLSTNLG+LTCI+CSG+HRELGV +SRMQSLT Sbjct: 2 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT 61 Query: 483 LDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR 542 LD+LG SELLLA N+GN FNE+ME LPS KP+ SDM R+DYI AKY+E R+AR Sbjct: 62 LDVLGTSELLLAKNIGNAGFNEIMECCLPSEDPVKPNPGSDMIARKDYITAKYMERRYAR 121 Query: 543 R----CTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVAN 598 + + L A+ RD+ +L+A+A+G D + +P + P+E LHLAV+ + Sbjct: 122 KKHADTAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD 181 Query: 599 QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETA 658 + SL +VDF++QN G+LD + G+TALHY L + +CLKLLL+G+A + NE+GET Sbjct: 182 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP 241 Query: 659 LDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVIS 695 LDIA++ H+ CEELL QA +G F +HV+Y W + Sbjct: 242 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLL 278 >3T9K-A nrPDB Length = 390 Score = 306 bits (783), Expect = 4e-83, Method: Composition-based stats. Identities = 101/359 (28%), Positives = 150/359 (41%), Gaps = 65/359 (18%) Query: 406 SAGPGSWGSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCS 465 SA G EP + ++A+V+S GN+QCCDC P W S NLGV CIQCS Sbjct: 14 SAATLGSGGMARGREPGGVGH-VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCS 72 Query: 466 GVHRELGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMG 525 G+HR LGV FS+++SLTLD P + L +GN N++ EA++ + KP Sbjct: 73 GIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQ 132 Query: 526 TRRDYIMAKYVEHRFAR----------------------------------RCTPEP--Q 549 + +I AKYVE +F R PEP + Sbjct: 133 EKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGDLRSKPEPPSE 192 Query: 550 RLWT----AICNR------DLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQ 599 L + A+ R L ++ +A A+G D G D P ++ Sbjct: 193 DLGSLHPGALLFRASGHPPSLPTMADALAHGADVNWVNGGQDNATP-------LIQATAA 245 Query: 600 ASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETAL 659 SL +F++QNG +++ + G LH+A + L LK A +G + G L Sbjct: 246 NSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPL 305 Query: 660 DIARKKHHKECEELLE----------QAQAGTFAF-PLHVDYSWVISTEPGSDSEEDEE 707 IA + + + LL Q QAG + + D+S + S +P S + Sbjct: 306 TIAMETANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHD 364 >6BY9-A nrPDB Length = 328 Score = 303 bits (777), Expect = 2e-82, Method: Composition-based stats. Identities = 76/312 (24%), Positives = 126/312 (40%), Gaps = 43/312 (13%) Query: 514 GGPKPSAESDMGTRRDYIMAKYV--EHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQ 571 G +P+ G ++ + + + + ++ P++L+ + +L VL +G Sbjct: 32 GLGRPTPGLSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGI 91 Query: 572 DFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAAL 631 D + + ++P LH A A + + ++Q G ++D + D T L AA Sbjct: 92 DPNFKMEHQNKRSP----LHAA---AEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAE 144 Query: 632 YNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKE-CEELLEQAQAGTFA------F 684 N + +K L+K ALV + G T L +A KK H E + LL Q Sbjct: 145 NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWT 204 Query: 685 PL-------HVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWA--SGRLDISNKTYET 735 P+ HVD ++ ++ + D EE CL HWA SG +DI+ Sbjct: 205 PMIWATEYKHVDLVKLLLSKGSDINIRDNEENICL-------HWAAFSGCVDIAEILLAA 257 Query: 736 VASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETP---ES 792 L A G+S P+ ++R C S+V +L ++ ETP S Sbjct: 258 KCDLHAVNIHGDS-------PLHIAARENRYDCVVLFLSRDSDV-TLKNKEGETPLQCAS 309 Query: 793 LGSPASSSSLMS 804 L S S+ MS Sbjct: 310 LNSQVWSALQMS 321 >3B7B-A nrPDB Length = 237 Score = 270 bits (690), Expect = 2e-72, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 100/250 (40%), Gaps = 41/250 (16%) Query: 574 GQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYN 633 + + ++P LH A A + + ++Q G ++D + D T L AA N Sbjct: 3 NFKMEHQNKRSP----LHAA---AEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENN 55 Query: 634 QPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKE-CEELLEQAQAGTFA------FPL 686 + +K L+K ALV + G T L +A KK H E + LL Q P+ Sbjct: 56 HLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPM 115 Query: 687 -------HVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWA--SGRLDISNKTYETVA 737 HVD ++ ++ + D EE CL HWA SG +DI+ Sbjct: 116 IWATEYKHVDLVKLLLSKGSDINIRDNEENICL-------HWAAFSGCVDIAEILLAAKC 168 Query: 738 SLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETP---ESLG 794 L A G+S P+ ++R C S+V +L ++ ETP SL Sbjct: 169 DLHAVNIHGDS-------PLHIAARENRYDCVVLFLSRDSDV-TLKNKEGETPLQCASLN 220 Query: 795 SPASSSSLMS 804 S S+ MS Sbjct: 221 SQVWSALQMS 230 >5C6R-A nrPDB Length = 150 Score = 251 bits (641), Expect = 9e-67, Method: Composition-based stats. Identities = 86/123 (69%), Positives = 101/123 (82%) Query: 289 GYSIHQHQGNKQFGTEKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKLTL 348 GYS+HQ QGNK++G+EK GFL KKSDGIR+VWQ+RKC VK G LTISH+T NR P KL L Sbjct: 25 GYSMHQLQGNKEYGSEKKGFLLKKSDGIRKVWQRRKCAVKNGILTISHATSNRQPAKLNL 84 Query: 349 LTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAG 408 LTCQV+PN E+KK FDL++HNRTYHFQAEDE + AW+SVL NSK+EAL+ AF GE S G Sbjct: 85 LTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNSKEEALTMAFRGEQSTG 144 Query: 409 PGS 411 S Sbjct: 145 ENS 147 >2DA0-A nrPDB Length = 114 Score = 210 bits (534), Expect = 2e-54, Method: Composition-based stats. Identities = 74/105 (70%), Positives = 87/105 (82%), Gaps = 1/105 (0%) Query: 304 EKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKLTLLTCQVRPNPEEKKCF 363 EK G+L KKSDGIR+VWQ+RKC VK G LTISH+T NR P KL LLTCQV+PN E+KK F Sbjct: 11 EKKGYLLKKSDGIRKVWQRRKCSVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSF 70 Query: 364 DLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAG 408 DL++HNRTYHFQAEDE + AW+SVL NSK+EAL+ AF G PS+G Sbjct: 71 DLISHNRTYHFQAEDEQDYVAWISVLTNSKEEALTMAFSG-PSSG 114 >3FM8-C nrPDB Length = 392 Score = 192 bits (487), Expect = 8e-49, Method: Composition-based stats. Identities = 49/152 (32%), Positives = 77/152 (50%), Gaps = 10/152 (6%) Query: 426 KLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDL 485 + + E+ RPGN++C DCGA DP W S LGV C+ CSG+HR + + S+++S+ LD Sbjct: 24 RRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIP-QVSKVKSVRLDA 82 Query: 486 LGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCT 545 +++ + GN + E+++PS +P+ R +I AKY F Sbjct: 83 WEEAQVEFMASHGNDAARARFESKVPSFYY-RPTPSDCQLLREQWIRAKYERQEF---IY 138 Query: 546 PEPQRLWTAICNRDLLSVLEAFANGQDFGQPL 577 PE Q ++A L + G+D GQ L Sbjct: 139 PEKQEPYSAGYREGFL-----WKRGRDNGQFL 165 Score = 32.8 bits (73), Expect = 0.70, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 42/123 (34%), Gaps = 17/123 (13%) Query: 289 GYSIHQHQGNKQFGTEKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKL-- 346 G+ + + N QF + K F+ + +G + + + + I H P K+ Sbjct: 152 GFLWKRGRDNGQFLSRK--FVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGH 209 Query: 347 --TLLTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGE 404 L ++ N R ED E W + L+ ++ L AF G Sbjct: 210 PHGLQVTYLKDNS-----------TRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA 258 Query: 405 PSA 407 A Sbjct: 259 SDA 261 >2CRR-A nrPDB Length = 141 Score = 168 bits (426), Expect = 9e-42, Method: Composition-based stats. Identities = 39/104 (37%), Positives = 61/104 (58%) Query: 410 GSWGSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHR 469 GS GS+G + ++ +L+++++ N C DC A P W S N+GV CI+C+G+HR Sbjct: 1 GSSGSSGKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHR 60 Query: 470 ELGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSH 513 LGV SR++S+ LD ++ +MGNT + EA LP + Sbjct: 61 NLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPEN 104 >2IQJ-A nrPDB Length = 134 Score = 157 bits (398), Expect = 1e-38, Method: Composition-based stats. Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 6/131 (4%) Query: 415 AGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVR 474 G + D + ++A + N C DC + P W S N+GV CI+C+G+HR LGV Sbjct: 4 TGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVH 63 Query: 475 FSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPS-HGGPKPSAESDMGTRRDYIMA 533 SR++S+ LD ++ MGN N + EA LP P+ +I Sbjct: 64 ISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV-----EGFIRD 118 Query: 534 KYVEHRFARRC 544 KY + ++ R Sbjct: 119 KYEKKKYMDRS 129 >2P57-A nrPDB Length = 144 Score = 149 bits (375), Expect = 6e-36, Method: Composition-based stats. Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 8/134 (5%) Query: 406 SAGPGSWGSAGHDGEPHD-LTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQC 464 S+G GSA EP+ + L +++ P N C DCGA +P+W S GV CI C Sbjct: 8 SSGLVPRGSA----EPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDC 63 Query: 465 SGVHRELGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDM 524 SGVHR LGV S ++S LD L + +G N A HG A + Sbjct: 64 SGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGG---NANATAFFRQHGCTANDANTKY 120 Query: 525 GTRRDYIMAKYVEH 538 +R + + + Sbjct: 121 NSRAAQMYREKIRQ 134 >5AQ9-A nrPDB Length = 422 Score = 144 bits (364), Expect = 1e-34, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D A + A L +V+ ++++G +DA Sbjct: 17 KLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 76 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G T LH AA + + +++LLK A V ++ G T L +A K + E E+L + Sbjct: 77 DVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHG 136 Query: 679 AGTFAFPLHVDYSWVISTEPGSDSE 703 A A + ++ + G+D Sbjct: 137 ADVNAQDKFGKTPFDLADDNGNDDV 161 Score = 132 bits (333), Expect = 5e-31, Method: Composition-based stats. Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 9/131 (6%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A + L V +G D + LHLA A L +V+ +++ Sbjct: 51 LHLAAYSGHLEIVEVLLKHGADVDA------SDVFGYTPLHLA---AYWGHLEIVEVLLK 101 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 NG ++A +DG T LH AA + + +++LLK A V ++ G+T D+A + + Sbjct: 102 NGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDV 161 Query: 671 EELLEQAQAGT 681 LL+ A A Sbjct: 162 GTLLQVAAAAD 172 Score = 61.7 bits (148), Expect = 2e-09, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 38/111 (34%), Gaps = 9/111 (8%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A L V NG D D P LHLA A L +V+ +++ Sbjct: 84 LHLAAYWGHLEIVEVLLKNGADVNAM--DSDGMTP----LHLA---AKWGYLEIVEVLLK 134 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDI 661 +G ++A+ G T A D LL A G LD+ Sbjct: 135 HGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAADQLGARVGYIELDL 185 >5AQA-A nrPDB Length = 418 Score = 144 bits (363), Expect = 1e-34, Method: Composition-based stats. Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D A + A L +V+ ++++G +DA Sbjct: 17 KLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 76 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G T LH AA + + +++LLK A V ++ G T L +A K +KE E+L +A Sbjct: 77 DVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAG 136 Query: 679 AGTFAFPLH-VDYSWVISTEP 698 A A W+ + + Sbjct: 137 ADVDAQDKFGKRPLWLAADQG 157 Score = 120 bits (301), Expect = 3e-27, Method: Composition-based stats. Identities = 36/140 (25%), Positives = 60/140 (42%), Gaps = 9/140 (6%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A + L V +G D + LHLA A L +V+ +++ Sbjct: 51 LHLAAYSGHLEIVEVLLKHGADVDA------SDVFGYTPLHLA---AYWGHLEIVEVLLK 101 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 NG ++A +DG T LH AA + + +++LLK A V ++ G+ L +A + H E Sbjct: 102 NGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEI 161 Query: 671 EELLEQAQAGTFAFPLHVDY 690 L A+ + +D Sbjct: 162 AAKLVAARLKARVGYIELDL 181 >3O47-A nrPDB Length = 329 Score = 143 bits (361), Expect = 3e-34, Method: Composition-based stats. Identities = 45/148 (30%), Positives = 71/148 (47%), Gaps = 9/148 (6%) Query: 424 LTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTL 483 T+ ++ EV+ + N+ C +CGA +P W+S G+ C++CSG HR LGV S ++S+T+ Sbjct: 23 RTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTM 82 Query: 484 DLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTR-----RDYIMAKYVEH 538 D EL GN F E +E+Q P S + +R RD ++A Sbjct: 83 DKWKDIELEKMKAGGNAKFREFLESQ--EDYDPCWSLQEKYNSRAAALFRDKVVALAEGR 140 Query: 539 RFARRCTPEPQRLWTAICNRDLLSVLEA 566 ++ +P + WT R L E Sbjct: 141 EWSLESSPA--QNWTPPQPRGLFGKKEM 166 >5H76-A nrPDB Length = 201 Score = 142 bits (359), Expect = 4e-34, Method: Composition-based stats. Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 10/138 (7%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D A + A L +V+ ++++G +DA Sbjct: 9 KLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 68 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELL---- 674 G T LH AA + + +++LLK A V ++ G T L +A K + E E+L Sbjct: 69 DVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHG 128 Query: 675 ---EQAQAGTFAFPLHVD 689 Q + G AF + +D Sbjct: 129 AVNAQDKFGKTAFDISID 146 Score = 119 bits (297), Expect = 7e-27, Method: Composition-based stats. Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 16/138 (11%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A + L V +G D + LHLA A L +V+ +++ Sbjct: 43 LHLAAYSGHLEIVEVLLKHGADVDA------SDVFGYTPLHLA---AYWGHLEIVEVLLK 93 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 NG ++A +DG T LH AA + + +++LLK A V ++ G+TA DI+ +++ Sbjct: 94 NGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDL 152 Query: 671 EELLEQAQAGTFAFPLHV 688 ++L F LH+ Sbjct: 153 AQIL------AFYEILHL 164 >5NZS-P nrPDB Length = 520 Score = 141 bits (355), Expect = 2e-33, Method: Composition-based stats. Identities = 39/135 (28%), Positives = 54/135 (40%), Gaps = 3/135 (2%) Query: 418 DGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSR 477 G + L +++ P N C DCGA P+W S GV CI CSGVHR LGV S Sbjct: 3 AGPSKSEIQTLFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSF 62 Query: 478 MQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVE 537 ++S LD L + +G N A HG A + +R + + + Sbjct: 63 IRSTELDSNWSWLQLRCMQVGG---NANATAFFRQHGCLANDANTKYNSRAAQMYREKIR 119 Query: 538 HRFARRCTPEPQRLW 552 + LW Sbjct: 120 QLGSTALARHGTDLW 134 >3DWD-A nrPDB Length = 147 Score = 139 bits (350), Expect = 6e-33, Method: Composition-based stats. Identities = 36/104 (34%), Positives = 56/104 (53%), Gaps = 2/104 (1%) Query: 424 LTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTL 483 T+ ++ EV+ + N+ C +CGA +P W+S G+ C++CSG HR LGV S ++S+T+ Sbjct: 24 RTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTM 83 Query: 484 DLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTR 527 D EL GN F E +E+Q P S + +R Sbjct: 84 DKWKDIELEKMKAGGNAKFREFLESQ--EDYDPCWSLQEKYNSR 125 >5AQB-A nrPDB Length = 428 Score = 138 bits (348), Expect = 1e-32, Method: Composition-based stats. Identities = 44/155 (28%), Positives = 67/155 (43%), Gaps = 17/155 (10%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELV---LHLAVKVANQASLPLVDFIIQNGGHL 615 +LEA GQD + G D A +E+ LHLA L +V+ +++NG + Sbjct: 17 KLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAA----WGHLEIVECLLKNGADV 72 Query: 616 DAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 675 +A DG T LH AA + +++LLK A V ++AG T L +A H E E+L Sbjct: 73 NAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLL 132 Query: 676 QAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKR 710 + A A P + ++ E Sbjct: 133 KNGADVNAQDKF-------GKTPRDLAIDNGNEDI 160 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 9/112 (8%) Query: 567 FANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL 626 NG D D P LHLA A L +V+ +++ G ++A G T L Sbjct: 66 LKNGADVN--AADIDGYTP----LHLA---AFSGHLEIVEVLLKYGADVNADDQAGFTPL 116 Query: 627 HYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 H AA++ + +++LLK A V ++ G+T D+A +++ E+L +A Sbjct: 117 HLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAA 168 Score = 68.2 bits (165), Expect = 2e-11, Method: Composition-based stats. Identities = 29/120 (24%), Positives = 45/120 (37%), Gaps = 13/120 (10%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A + L V G D D QA LHLA A L +V+ +++ Sbjct: 83 LHLAAFSGHLEIVEVLLKYGADVN-----ADDQA-GFTPLHLA---AIFGHLEIVEVLLK 133 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 NG ++A+ G T A D ++L K LV + A + + + + E Sbjct: 134 NGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAADQ----LGARVGYIEL 189 >2CRW-A nrPDB Length = 149 Score = 137 bits (345), Expect = 2e-32, Method: Composition-based stats. Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 3/126 (2%) Query: 427 LLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLL 486 + ++S P N C DCGA +P+W S GV CI CSG HR LGV S ++S LD Sbjct: 18 TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSN 77 Query: 487 GPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTP 546 L + +G N + HG + +R + + ++ ++ Sbjct: 78 WSWFQLRCMQVGG---NASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSLASQATRK 134 Query: 547 EPQRLW 552 LW Sbjct: 135 HGTDLW 140 >5AQ7-A nrPDB Length = 418 Score = 136 bits (343), Expect = 3e-32, Method: Composition-based stats. Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 4/141 (2%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D +E A + L +V+ +++NG ++A Sbjct: 17 KLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAN 76 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G+T LH AA + +++LLK A V + G L +A +KE E+L +A Sbjct: 77 DERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAG 136 Query: 679 AGTFAFPLH-VDYSWVISTEP 698 A A W+ + + Sbjct: 137 ADVDAQDKFGKRPLWLAADQG 157 Score = 111 bits (277), Expect = 1e-24, Method: Composition-based stats. Identities = 36/140 (25%), Positives = 57/140 (40%), Gaps = 9/140 (6%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A L V NG D P LHLA A L +V+ +++ Sbjct: 51 LHLAAWEGHLGIVEVLLKNGADVNANDE--RGHTP----LHLA---AYTGHLEIVEVLLK 101 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 NG ++A G LH AA++ + +++LLK A V ++ G+ L +A + H E Sbjct: 102 NGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEI 161 Query: 671 EELLEQAQAGTFAFPLHVDY 690 L A+ + +D Sbjct: 162 AAKLVAARLKARVGYIELDL 181 >5CBO-A nrPDB Length = 176 Score = 135 bits (339), Expect = 9e-32, Method: Composition-based stats. Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D A + + A +V+ +++ G ++A Sbjct: 6 KLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNAS 65 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELL--EQ 676 A G+T LH AA + +++LLK A V ++ G+TA DI+ +++ E+L + Sbjct: 66 DATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCKNK 125 Query: 677 AQAGTFAFPLHV 688 AQ F LH+ Sbjct: 126 AQQAAFYCILHM 137 Score = 113 bits (282), Expect = 4e-25, Method: Composition-based stats. Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 3/129 (2%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 ++ A+ V ++ NG ++A G T LH AA + + +++LLK A V + Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66 Query: 653 EAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCL 712 G+T L +A K + E+L + A A + + ED E C Sbjct: 67 ATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQD---KFGKTAFDISIDNGNEDLAEILCK 123 Query: 713 LKLPAQAHW 721 K A + Sbjct: 124 NKAQQAAFY 132 Score = 70.2 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 29/129 (22%), Positives = 47/129 (36%), Gaps = 18/129 (13%) Query: 626 LHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFA-- 683 L AA Q D +++L+ A V ++ G T L +A H E E+L + A A Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66 Query: 684 ----FPLHVDYSW-------VISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKT 732 PLH+ W V+ + +D+ K +G D++ Sbjct: 67 ATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDK-----FGKTAFDISIDNGNEDLAEIL 121 Query: 733 YETVASLGA 741 + A A Sbjct: 122 CKNKAQQAA 130 >6FES-A nrPDB Length = 367 Score = 134 bits (338), Expect = 1e-31, Method: Composition-based stats. Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 3/127 (2%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D +E A + L +V+ +++NG ++A Sbjct: 9 KLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAN 68 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G+T LH AA + +++LLK A V + G L +A H+E E+L + Sbjct: 69 DERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNG 128 Query: 679 AGTFAFP 685 A A Sbjct: 129 ADARAQD 135 Score = 111 bits (278), Expect = 1e-24, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 48/127 (37%), Gaps = 13/127 (10%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 ++ A V ++ NG ++ G T LH AA +++LLK A V + Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 69 Query: 653 EAGETALDIARKKHHKECEELLEQAQAGTFAFPL-------------HVDYSWVISTEPG 699 E G T L +A H E E+L + AG A + H + V+ Sbjct: 70 ERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGA 129 Query: 700 SDSEEDE 706 +D+ Sbjct: 130 DARAQDK 136 Score = 110 bits (276), Expect = 2e-24, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 9/126 (7%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A L V NG D P LHLA A L +V+ +++ Sbjct: 43 LHLAAWEGHLGIVEVLLKNGADVNANDE--RGHTP----LHLA---AYTGHLEIVEVLLK 93 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 NG ++A G LH AA++ + +++LLK A ++ G+T D+AR ++ Sbjct: 94 NGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESV 153 Query: 671 EELLEQ 676 L + Sbjct: 154 ARLARK 159 >6MWQ-A nrPDB Length = 493 Score = 125 bits (313), Expect = 1e-28, Method: Composition-based stats. Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 6/162 (3%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D A + L A + L +V+ +++ G ++A Sbjct: 8 KLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAA 67 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G T LH AA + +++LLK A V ++ G+T L + H E E+L + Sbjct: 68 DLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHG 127 Query: 679 AGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAH 720 A A + + ED E L L AH Sbjct: 128 ADVNAQD---KFGKTAFDISIDNGNEDLAEILQKLNLSDIAH 166 >3SUB-A nrPDB Length = 163 Score = 122 bits (307), Expect = 5e-28, Method: Composition-based stats. Identities = 29/77 (37%), Positives = 42/77 (54%) Query: 433 KSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELL 492 K N++C DCG ++P W+S N G+ CI CSGVHR LGV S ++S+ +D+ +L Sbjct: 17 KEDESNNKCFDCGISNPDWVSVNHGIFLCINCSGVHRSLGVHISIVRSIKMDIFTDEQLK 76 Query: 493 LALNMGNTSFNEVMEAQ 509 GN +E Sbjct: 77 YIDKGGNKKCQTYLENY 93 >2OWA-A nrPDB Length = 138 Score = 121 bits (302), Expect = 2e-27, Method: Composition-based stats. Identities = 33/99 (33%), Positives = 48/99 (48%) Query: 432 VKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSEL 491 V++RP N C DC + +PTWLS + V C+ CS HR++GV S ++S LD P +L Sbjct: 30 VRNRPENRTCFDCESRNPTWLSLSFAVFICLNCSSDHRKMGVHISFVRSSDLDKFTPIQL 89 Query: 492 LLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDY 530 + GN + L + PK + R Y Sbjct: 90 VRMDIGGNGRARNYFKQVLGVNFSPKTKEYASSICGRQY 128 >5MIO-C nrPDB Length = 573 Score = 119 bits (298), Expect = 6e-27, Method: Composition-based stats. Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 3/154 (1%) Query: 562 SVLEAFANGQDFGQPL---PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAK 618 +LEA GQD + G D A + L A L +V+ ++++G + A Sbjct: 413 KLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSAS 472 Query: 619 AADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G+T LH AAL + +++LLK A V V+ G+T L +A H + E L + Sbjct: 473 DLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHG 532 Query: 679 AGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCL 712 A A ++ S + GS+ + +K L Sbjct: 533 ADVNAQDKFGKTAYDTSIDNGSEDLAEILQKLNL 566 Score = 101 bits (252), Expect = 1e-21, Method: Composition-based stats. Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 9/126 (7%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L A L V +G D + LHLA + L +V+ +++ Sbjct: 447 LHLAATYGHLEIVEVLLKHGADVSA------SDLMGSTPLHLAALI---GHLEIVEVLLK 497 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKEC 670 +G ++A G+T L AA+ ++ LLK A V ++ G+TA D + ++ Sbjct: 498 HGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDL 557 Query: 671 EELLEQ 676 E+L++ Sbjct: 558 AEILQK 563 >6AUN-A nrPDB Length = 752 Score = 92.9 bits (229), Expect = 6e-19, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 43/82 (52%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 A + + + +++ G +D+ +A GNTALH A + N+ DC+ +LL A GT Sbjct: 288 ASPLHWAKNAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPG 347 Query: 653 EAGETALDIARKKHHKECEELL 674 E G T L +A K + E + L Sbjct: 348 EHGNTPLHLAISKDNMEMIKAL 369 Score = 75.2 bits (183), Expect = 1e-13, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 74/221 (33%), Gaps = 33/221 (14%) Query: 588 LVLHLAVKVANQASLPLVDFIIQN-GGHLDAKAADGNTALHYAALYNQPDCLKLLLKGR- 645 LHLA + + ++ ++Q +D G TA HYA + L+LL K Sbjct: 154 TPLHLACRKGDS---EILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNAS 210 Query: 646 ALVGTVNEAGETALDIARKKHHKECEELLEQAQA-----GTFAFPLHVDY--------SW 692 A + VN+ G T L +A + +E +L A G FP+H Sbjct: 211 AGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAEM 270 Query: 693 VISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCP 752 +IS + +D + HWA +++ + + + + G + Sbjct: 271 IISMDSSQIHSKDPR------YGASPLHWAKN-AEMARMLLKRGCDVDSTSAAGNTA--- 320 Query: 753 PPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETPESL 793 + + C + + E TP L Sbjct: 321 ----LHVAVMRNRFDCVMVLLTYGANAGT-PGEHGNTPLHL 356 Score = 64.4 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 46/207 (22%), Positives = 77/207 (37%), Gaps = 25/207 (12%) Query: 485 LLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESD----MGTRRDYIMAKYVEHRF 540 +G E++ L + N N + + P H K S + + I +K + R+ Sbjct: 229 QMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAEMIISMDSSQIHSK--DPRY 286 Query: 541 ARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQA 600 N ++ +L G D A LH+AV + Sbjct: 287 GA-------SPLHWAKNAEMARML--LKRGCDVD------STSAAGNTALHVAVM---RN 328 Query: 601 SLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALD 660 V ++ G + GNT LH A + + +K L+ A V T N+ GET Sbjct: 329 RFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAF 388 Query: 661 IARKKHHKECEELLEQAQAGTFAFPLH 687 +A K K+ ++L+ ++A AF L Sbjct: 389 MASKIS-KQLQDLMPISRARKPAFILS 414 Score = 52.8 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 50/119 (42%), Gaps = 12/119 (10%) Query: 581 DAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-GNTALHYAALYNQPDCLK 639 + P +H A+K + + ++ I + + +K G + LH+A + + Sbjct: 247 NVMGPSGFPIHTAMKFSQKGCAEMI--ISMDSSQIHSKDPRYGASPLHWA---KNAEMAR 301 Query: 640 LLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT------FAFPLHVDYSW 692 +LLK V + + AG TAL +A ++ +C +L A PLH+ S Sbjct: 302 MLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISK 360 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 80/257 (31%), Gaps = 41/257 (15%) Query: 548 PQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDF 607 P+ + L S +A N Q F LP ++S+ ++ Sbjct: 62 PRNPHSGFRLFQLESEADALVNFQQFSSQLP-----------------PFYESSVQVLHV 104 Query: 608 -IIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKH 666 ++Q+ L ++ T H A +C T NE G T L +A +K Sbjct: 105 EVLQHLSDL-IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKG 163 Query: 667 HKECEELLEQ---AQAGT--------FAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKL 715 E L Q AQ F + + D S V+ + S + + L Sbjct: 164 DSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVNKQGLT- 222 Query: 716 PAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGD 775 P G+ ++ A P G P+ + + +GCA Sbjct: 223 PLHLACQMGKQEMVRVLLLCNARCNVMGPSG--------FPIHTAMKFSQKGCAEMIISM 274 Query: 776 RSEVSSLSSEAPETPES 792 S S + S+ P S Sbjct: 275 DS--SQIHSKDPRYGAS 289 >4NIK-A nrPDB Length = 230 Score = 88.7 bits (218), Expect = 1e-17, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 71/203 (34%), Gaps = 36/203 (17%) Query: 588 LVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRAL 647 LH A +V+F++Q G ++ K G + LH AA + + +K LL A Sbjct: 46 TALHWACS---AGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 102 Query: 648 VGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEE 707 V VN+ G T L A K+ E +L + A A +D Sbjct: 103 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA--------------------KDHY 142 Query: 708 EKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQG 767 E + + A G L + + AS +G + P+ + Sbjct: 143 EATAMHRAA-----AKGNLKMIHILLYYKASTNIQDTEGNT-------PLHLACDEERVE 190 Query: 768 CARHASGDRSEVSSLSSEAPETP 790 A+ + + + ++ +TP Sbjct: 191 EAKLLVSQGASIY-IENKEEKTP 212 Score = 67.5 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 48/134 (35%), Gaps = 20/134 (14%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G A + A++ + +++ G + DAK TA+H AA + Sbjct: 100 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMI 159 Query: 639 KLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEP 698 +LL +A + G T L +A V+ + ++ ++ Sbjct: 160 HILLYYKASTNIQDTEGNTPLHLA--------------------CDEERVEEAKLLVSQG 199 Query: 699 GSDSEEDEEEKRCL 712 S E++EEK L Sbjct: 200 ASIYIENKEEKTPL 213 Score = 62.5 bits (150), Expect = 8e-10, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 38/86 (44%) Query: 578 PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDC 637 G + A + + A + +L ++ ++ + + +GNT LH A + + Sbjct: 132 GGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEE 191 Query: 638 LKLLLKGRALVGTVNEAGETALDIAR 663 KLL+ A + N+ +T L +A+ Sbjct: 192 AKLLVSQGASIYIENKEEKTPLQVAK 217 >5JHQ-A nrPDB Length = 482 Score = 86.7 bits (213), Expect = 4e-17, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 87/257 (33%), Gaps = 49/257 (19%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G + A ++ L + +V ++ G +A+ T LH AA+ + D Sbjct: 72 GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVC 131 Query: 639 KLLLKGRALVGTVNEAGETALDIARK------KHHKECEELLEQAQAGTFAFPLHVDYSW 692 +LL+ A N G++ALD+A + +ELLE A++G + Sbjct: 132 IVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGN-------EEKL 184 Query: 693 VISTEPGSDSEEDEEEKRCLLKLPAQAHWASG--RLDISNKTYETVASLGAATPQGESED 750 + P + + + + H A+G R+ I + A + A +D Sbjct: 185 MALLTPLNVNCHASD-----GRKSTPLHLAAGYNRVRIVQLLLQHGADVHA-------KD 232 Query: 751 CPPPLPVKNSSRTLVQGCARH----------------------ASGDRSEVSSLSSEAPE 788 +P+ N+ AS +R EV SL Sbjct: 233 KGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGA 292 Query: 789 TPESLGSPASSSSLMSP 805 P + S+ M+P Sbjct: 293 DPTLVNCHGKSAVDMAP 309 Score = 79.4 bits (194), Expect = 6e-15, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 51/132 (38%), Gaps = 6/132 (4%) Query: 549 QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFI 608 L A DL V + A P E LH AV + + + + Sbjct: 324 HSLLQAAREADLAKVKKTLALEI-INFKQPQS-----HETALHCAVASLHPKRKQVTELL 377 Query: 609 IQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHK 668 ++ G +++ K D T LH AA D +++L K A + ++ G+TAL A H Sbjct: 378 LRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHL 437 Query: 669 ECEELLEQAQAG 680 + LL + Sbjct: 438 QTCRLLLSYGSD 449 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 49/113 (43%), Gaps = 13/113 (11%) Query: 565 EAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNT 624 G + + D P LH+A A +A +++ + ++G ++A G T Sbjct: 376 LLLRKGANVNEKN--KDFMTP----LHVA---AERAHNDVMEVLHKHGAKMNALDTLGQT 426 Query: 625 ALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQA 677 ALH AAL +LLL + ++ G T A + ++ +++L ++ Sbjct: 427 ALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSES 475 Score = 55.5 bits (132), Expect = 1e-07, Method: Composition-based stats. Identities = 34/181 (18%), Positives = 56/181 (30%), Gaps = 28/181 (15%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQ-----APE-------ELVLHLAVKVAN 598 L A + ++G D + PE E H ++ A Sbjct: 272 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAR 331 Query: 599 QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQP---DCLKLLLKGRALVGTVNEAG 655 +A L V + + TALH A P +LLL+ A V N+ Sbjct: 332 EADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDF 391 Query: 656 ETALDIARKKHHKECEELLEQAQAGTFAFPL-------------HVDYSWVISTEPGSDS 702 T L +A ++ H + E+L + A A H+ ++ + S Sbjct: 392 MTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPS 451 Query: 703 E 703 Sbjct: 452 I 452 Score = 38.2 bits (87), Expect = 0.018, Method: Composition-based stats. Identities = 39/243 (16%), Positives = 84/243 (34%), Gaps = 29/243 (11%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G A + + A++ + + ++ +G G +A+ A + L Sbjct: 258 GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 317 Query: 639 KLLLKGRALVGTVNEAGETALDIARKKHHKECEEL-LEQAQAGTFAFPLHV--------D 689 KG +L+ EA D+A+ K E + +Q Q+ A V Sbjct: 318 TYEFKGHSLLQAAREA-----DLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQ 372 Query: 690 YSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESE 749 + ++ + + +E++++ L +AH D+ ++ A + A G++ Sbjct: 373 VTELLLRKGANVNEKNKDFMTPLHVAAERAH-----NDVMEVLHKHGAKMNALDTLGQTA 427 Query: 750 DCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETPESLGSPASSS--SLMSPLE 807 + ++ R S+ S+ S T +G+ A S +P+ Sbjct: 428 -------LHRAALAGHLQTCRLLLSYGSD-PSIISLQGFTAAQMGNEAVQQILSESTPIR 479 Query: 808 PGD 810 D Sbjct: 480 TSD 482 >2DWZ-A nrPDB Length = 231 Score = 86.0 bits (211), Expect = 8e-17, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 70/203 (34%), Gaps = 36/203 (17%) Query: 588 LVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRAL 647 LH A +V+F++Q G ++ K G + LH AA + + +K LL A Sbjct: 42 TALHWACS---AGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAH 98 Query: 648 VGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEE 707 V VN+ G T L A K+ E +L + A A H D + + Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-HYDATAM-------------- 143 Query: 708 EKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQG 767 A G L + + AS +G + P+ + Sbjct: 144 ----------HRAAAKGNLKMVHILLFYKASTNIQDTEGNT-------PLHLACDEERVE 186 Query: 768 CARHASGDRSEVSSLSSEAPETP 790 A+ + + + ++ +TP Sbjct: 187 EAKFLVTQGASIY-IENKEEKTP 208 Score = 66.7 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 27/136 (19%), Positives = 48/136 (35%), Gaps = 20/136 (14%) Query: 577 LPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPD 636 + G A + A++ + +++ G + DAK TA+H AA Sbjct: 94 VKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLK 153 Query: 637 CLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVIST 696 + +LL +A + G T L +A V+ + + T Sbjct: 154 MVHILLFYKASTNIQDTEGNTPLHLA--------------------CDEERVEEAKFLVT 193 Query: 697 EPGSDSEEDEEEKRCL 712 + S E++EEK L Sbjct: 194 QGASIYIENKEEKTPL 209 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 37/86 (43%) Query: 578 PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDC 637 G + A + + A + +L +V ++ + + +GNT LH A + + Sbjct: 128 GGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEE 187 Query: 638 LKLLLKGRALVGTVNEAGETALDIAR 663 K L+ A + N+ +T L +A+ Sbjct: 188 AKFLVTQGASIYIENKEEKTPLQVAK 213 >4Z68-A nrPDB Length = 155 Score = 84.4 bits (207), Expect = 2e-16, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 581 DAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKL 640 D + + LH A A + +V++++Q+G + AK G LH A Y + +L Sbjct: 32 DIEGRQSTPLHFA---AGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAEL 88 Query: 641 LLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAG 680 L+K A+V + T L A K E +LL Q A Sbjct: 89 LVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGAD 128 Score = 79.4 bits (194), Expect = 7e-15, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 1/97 (1%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G D A ++ L + + + ++++G ++ T LH AA + + Sbjct: 60 GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 119 Query: 639 KLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 675 KLLL+ A N G T LD+ + + ++LL Sbjct: 120 KLLLQHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLR 155 Score = 69.4 bits (168), Expect = 7e-12, Method: Composition-based stats. Identities = 38/182 (20%), Positives = 64/182 (35%), Gaps = 37/182 (20%) Query: 593 AVKVANQASLPLVDFI--IQNGGHLDAKAADGN--TALHYAALYNQPDCLKLLLKGRALV 648 ++ A + V + +Q+ ++ + +G T LH+AA YN+ ++ LL+ A V Sbjct: 7 LLEAAKAGDVETVKKLCTVQS---VNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63 Query: 649 GTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEE 708 ++ G L A H E ELL + A L W + Sbjct: 64 HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL-----WKFT------------- 105 Query: 709 KRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGC 768 P A G+ +I + A P ++ D PL + T +Q Sbjct: 106 -------PLHEAAAKGKYEICKLLLQ-----HGADPTKKNRDGNTPLDLVKDGDTDIQDL 153 Query: 769 AR 770 R Sbjct: 154 LR 155 >2OLM-A nrPDB Length = 140 Score = 82.9 bits (203), Expect = 6e-16, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 50/129 (38%), Gaps = 5/129 (3%) Query: 413 GSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHREL- 471 GS+ + + ++ ++ P N +C DC PT+++ +G C CSG R L Sbjct: 1 GSSAK-RKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 59 Query: 472 GVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYI 531 R++S+++ E+ GN ++ P + ++ Sbjct: 60 PPH--RVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FL 116 Query: 532 MAKYVEHRF 540 KY + R+ Sbjct: 117 QEKYEKKRW 125 >2D9L-A nrPDB Length = 134 Score = 82.1 bits (201), Expect = 1e-15, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 51/132 (38%), Gaps = 13/132 (9%) Query: 410 GSWGSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHR 469 GS GS+G ++ ++ P N +C DC PT+++ +G C CSG R Sbjct: 1 GSSGSSG---------LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLR 51 Query: 470 EL-GVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRR 528 L R++S+++ E+ GN ++ P + Sbjct: 52 GLNPPH--RVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE 109 Query: 529 DYIMAKYVEHRF 540 ++ KY + R+ Sbjct: 110 -FLQEKYEKKRW 120 >3EU9-A nrPDB Length = 240 Score = 81.7 bits (200), Expect = 1e-15, Method: Composition-based stats. Identities = 41/187 (21%), Positives = 72/187 (38%), Gaps = 23/187 (12%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-GNTALHYAALYNQPDC 637 G D + P++ + L A + LV + I G +D D +T LH+A Sbjct: 32 GYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSM 91 Query: 638 LKLLLKGRALVGTVNEAGETALDIARKKHHKECE-ELLEQAQAGTF------------AF 684 + L+K A ++ G + + +A + H L+ + Q A+ Sbjct: 92 VVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAY 151 Query: 685 PLH-VDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWA--SGRLDISNKTYETVASLGA 741 H VD + ++ T S + D+ K HWA +G + + E A++ A Sbjct: 152 RTHSVDPTRLLLTFNVSVNLGDKYHK------NTALHWAVLAGNTTVISLLLEAGANVDA 205 Query: 742 ATPQGES 748 +GES Sbjct: 206 QNIKGES 212 Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 43/246 (17%), Positives = 76/246 (30%), Gaps = 57/246 (23%) Query: 481 LTLDLLGPSELLLALNMG-NTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHR 539 +D +++ A G E++EA + +P E+ I + + Sbjct: 3 THIDDYSTWDIVKATQYGIYERCRELVEA---GYDVRQPDKENVTLLHWAAINNRIDLVK 59 Query: 540 FARRCTPEPQRLWT---------AICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVL 590 + +L A L V++ G D + Sbjct: 60 YYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDG------EGCSCI 113 Query: 591 HLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL------------------------ 626 HLA A +V ++I G +D +G T L Sbjct: 114 HLA---AQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVN 170 Query: 627 -----------HYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 675 H+A L + LLL+ A V N GE+ALD+A+++ + L+ Sbjct: 171 LGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQ 230 Query: 676 QAQAGT 681 +A+ Sbjct: 231 EARQAK 236 >5HKP-A nrPDB Length = 351 Score = 81.3 bits (199), Expect = 2e-15, Method: Composition-based stats. Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Query: 588 LVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRAL 647 LHLA A + +V ++Q+G + AK G LH A Y + +LLLK A Sbjct: 60 TPLHLA---AGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 116 Query: 648 VGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLH 687 V ++ T L A K+ E LL A H Sbjct: 117 VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCH 156 Score = 79.4 bits (194), Expect = 6e-15, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 51/132 (38%), Gaps = 6/132 (4%) Query: 549 QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFI 608 L A DL V + A P E LH AV + + + + Sbjct: 180 HSLLQAAREADLAKVKKTLALEI-INFKQPQS-----HETALHCAVASLHPKRKQVAELL 233 Query: 609 IQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHK 668 ++ G +++ K D T LH AA D +++L K A + ++ G+TAL A H Sbjct: 234 LRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHL 293 Query: 669 ECEELLEQAQAG 680 + LL + Sbjct: 294 QTCRLLLSYGSD 305 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 34/145 (23%), Positives = 52/145 (35%), Gaps = 27/145 (18%) Query: 614 HLDAKAADGN--TALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECE 671 +++ A+DG T LH AA YN+ ++LLL+ A V ++ G L A H E Sbjct: 48 NVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVT 107 Query: 672 ELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNK 731 ELL + A A L W + P + R+++ + Sbjct: 108 ELLLKHGACVNAMDL-----WQFT--------------------PLHEAASKNRVEVCSL 142 Query: 732 TYETVASLGAATPQGESEDCPPPLP 756 A G+S P P Sbjct: 143 LLSHGADPTLVNCHGKSAVDMAPTP 167 Score = 69.8 bits (169), Expect = 6e-12, Method: Composition-based stats. Identities = 46/271 (16%), Positives = 93/271 (34%), Gaps = 52/271 (19%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G D A ++ L + + + ++++G ++A T LH AA N+ + Sbjct: 81 GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVC 140 Query: 639 KLLLKGRALVGTVNEAGETALDIARK-----------KHHKECE---------------- 671 LLL A VN G++A+D+A K H + Sbjct: 141 SLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLAL 200 Query: 672 ELLEQAQAGTFAFPLH----------VDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHW 721 E++ Q + LH + ++ + + +E++++ L +AH Sbjct: 201 EIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAH- 259 Query: 722 ASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSEVSS 781 D+ ++ A + A G++ + ++ R S+ S Sbjct: 260 ----NDVMEVLHKHGAKMNALDSLGQTA-------LHRAALAGHLQTCRLLLSYGSD-PS 307 Query: 782 LSSEAPETPESLGSPASSS--SLMSPLEPGD 810 + S T +G+ A S +P+ D Sbjct: 308 IISLQGFTAAQMGNEAVQQILSESTPMRTSD 338 Score = 69.4 bits (168), Expect = 6e-12, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 54/122 (44%), Gaps = 7/122 (5%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G + + + A +A +++ + ++G ++A + G TALH AAL Sbjct: 237 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTC 296 Query: 639 KLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEP 698 +LLL + ++ G T A + ++ +++L ++ + VDY + +++ Sbjct: 297 RLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTPMRTS---DVDYRLLEASKA 349 Query: 699 GS 700 G Sbjct: 350 GD 351 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 50/150 (33%), Gaps = 15/150 (10%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQ-----APE-------ELVLHLAVKVAN 598 L A + ++G D + PE E H ++ A Sbjct: 128 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAR 187 Query: 599 QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQP---DCLKLLLKGRALVGTVNEAG 655 +A L V + + TALH A P +LLL+ A V N+ Sbjct: 188 EADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDF 247 Query: 656 ETALDIARKKHHKECEELLEQAQAGTFAFP 685 T L +A ++ H + E+L + A A Sbjct: 248 MTPLHVAAERAHNDVMEVLHKHGAKMNALD 277 >5GP7-A nrPDB Length = 169 Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 581 DAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKL 640 D Q LHLA A +L + ++++++G ++A+ G LH AA Y D L Sbjct: 38 DTQGRNSTPLHLA---AGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAAL 94 Query: 641 LLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAG 680 L+K V ++ T L A +K + LL A Sbjct: 95 LIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGAD 134 Score = 72.9 bits (177), Expect = 6e-13, Method: Composition-based stats. Identities = 35/148 (23%), Positives = 52/148 (35%), Gaps = 5/148 (3%) Query: 539 RFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPL--PGPDAQAPEELVLHLAVKV 596 R + CTPE L A N + + L G D A ++ L Sbjct: 24 RVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 83 Query: 597 ANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGE 656 A+ + + +I+ ++A T LH AA + LLL A N+ G+ Sbjct: 84 ASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 143 Query: 657 TALDIARKKHHKECEELLEQAQAGTFAF 684 T LD+A + LL A F Sbjct: 144 TPLDLATA---DDIRALLIDAMPENLYF 168 Score = 70.2 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 2/74 (2%) Query: 614 HLDAKAADGN--TALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECE 671 +++ + G T LH AA YN + + LL+ A V ++ G L A H + Sbjct: 33 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 92 Query: 672 ELLEQAQAGTFAFP 685 LL + A Sbjct: 93 ALLIKYNTCVNATD 106 >3ZKJ-A nrPDB Length = 261 Score = 77.1 bits (188), Expect = 3e-14, Method: Composition-based stats. Identities = 50/230 (21%), Positives = 80/230 (34%), Gaps = 26/230 (11%) Query: 595 KVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 654 + A + +I G ++ AD + LH A L C+K+LLK A V V Sbjct: 9 EAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTAD 68 Query: 655 GETALDIARKKHHKECEELLEQAQA-----GTFAFPL-------HVDYSWVISTEPGSDS 702 T L A +C LL Q A A P+ HV+ + G+ Sbjct: 69 WHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNI- 127 Query: 703 EEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSR 762 + K L P + + K E+ A + QG+ +D P+ +R Sbjct: 128 ----DHKISHLGTPLYLACENQQRACVKKLLESGADVN----QGKGQDS----PLHAVAR 175 Query: 763 TLVQGCARHASGDRSEVSSLSSEAPETPESLGSPASSSSLMSPLEPGDPS 812 T + A ++ + + + P L P S + + G PS Sbjct: 176 TASEELACLLMDFGADTQA-KNAEGKRPVELVPPESPLAQLFLEREGPPS 224 Score = 63.2 bits (152), Expect = 5e-10, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 1/111 (0%) Query: 573 FGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALY 632 L + PE + + A + + V+ +I GG++D K + T L+ A Sbjct: 85 VNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACEN 144 Query: 633 NQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFA 683 Q C+K LL+ A V + ++ L + +E LL A T A Sbjct: 145 QQRACVKKLLESGADVN-QGKGQDSPLHAVARTASEELACLLMDFGADTQA 194 >5DND-A nrPDB Length = 588 Score = 75.9 bits (185), Expect = 7e-14, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 47/94 (50%) Query: 586 EELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGR 645 + ++ LA+ +A+ L + +++ G L K ++G T LH AA + + +LL Sbjct: 419 DAVMPSLALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRG 478 Query: 646 ALVGTVNEAGETALDIARKKHHKECEELLEQAQA 679 V + G + L +A + H+EC LL +A A Sbjct: 479 MDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGA 512 Score = 55.5 bits (132), Expect = 1e-07, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 9/128 (7%) Query: 560 LLSVLEAFANGQDFGQPLP----GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHL 615 + S+ A A+ + G D + + L A +V ++ G + Sbjct: 422 MPSLALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDV 481 Query: 616 DAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN--EAGETALDIARKKHHKECEEL 673 +A+ DG + L A +C++LL K A + + +AG +A + + E L Sbjct: 482 NARDRDGLSPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASR---ADMEGL 538 Query: 674 LEQAQAGT 681 QAG Sbjct: 539 QAWGQAGA 546 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 45/140 (32%), Gaps = 20/140 (14%) Query: 630 ALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFP---- 685 A + + L+ L++ + + + G+T L +A + +L A Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489 Query: 686 ---------LHVDYSWVISTEPGSDSEEDEEE---KRCLLKLPAQAH----WASGRLDIS 729 H + ++ S +D ++ + C L A W D+ Sbjct: 490 SPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQAGADLQ 549 Query: 730 NKTYETVASLGAATPQGESE 749 Y+ ++L A G E Sbjct: 550 QPGYDGRSALCVAEAAGNQE 569 >2KXP-C nrPDB Length = 118 Score = 73.6 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 12/127 (9%) Query: 549 QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFI 608 + A+ N DL V + A G+D + L G + P LH A A+ L +++F+ Sbjct: 4 KEFMWALKNGDLDEVKDYVAKGEDVNRTLEG--GRKP----LHYA---ADCGQLEILEFL 54 Query: 609 IQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHK 668 + G ++A T L A C+KLLL A G TAL+ ++ Sbjct: 55 LLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALE---ATDNQ 111 Query: 669 ECEELLE 675 + LL+ Sbjct: 112 AIKALLQ 118 Score = 68.6 bits (166), Expect = 1e-11, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 32/83 (38%) Query: 600 ASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETAL 659 L V + G ++ G LHYAA Q + L+ LL A + ++ T L Sbjct: 13 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 72 Query: 660 DIARKKHHKECEELLEQAQAGTF 682 A + H C +LL A Sbjct: 73 LSAVYEGHVSCVKLLLSKGADKT 95 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 25/91 (27%), Gaps = 13/91 (14%) Query: 627 HYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFA--- 683 +A D +K + V E G L A E E L A A Sbjct: 7 MWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDK 66 Query: 684 ----------FPLHVDYSWVISTEPGSDSEE 704 + HV ++ ++ + + Sbjct: 67 HHITPLLSAVYEGHVSCVKLLLSKGADKTVK 97 >1G3N-B nrPDB Length = 168 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Query: 577 LPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPD 636 L G + + + A L + +++ ++ + +GN LH AA Sbjct: 58 LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLR 117 Query: 637 CLKLLLKGRA-LVGTVNEAGETALDIARKKHHKECEELLEQAQAG 680 ++ L+K A VG N G+TA D+AR E L++ AG Sbjct: 118 VVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 Score = 47.0 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 53/157 (33%), Gaps = 27/157 (17%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 A + L + ++QN +++A+ G TAL P+ + LL A + Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLKD 67 Query: 653 EAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCL 712 G + A + + + L + QA + ED E L Sbjct: 68 RTGFAVIHDAARAGFLDTLQTLLEFQA--------------------DVNIEDNEGNLPL 107 Query: 713 LKLPAQAHWASGRLDISNKTYE-TVASLGAATPQGES 748 + H L + + T +++G +G++ Sbjct: 108 HLAAKEGH-----LRVVEFLVKHTASNVGHRNHKGDT 139 >5ET1-A nrPDB Length = 353 Score = 70.9 bits (172), Expect = 3e-12, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 63/177 (35%), Gaps = 19/177 (10%) Query: 513 HGGPKPSAESDMGTRRDYIMAKY----VEHRFARRCTPEPQ-------RLWTAICNRDLL 561 H +A+++ G Y+ + V + C+ +P A Sbjct: 161 HYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHN 220 Query: 562 SVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD 621 VL + D D +H A A++ ++ +++ +G + ++ Sbjct: 221 PVLVWLVSFADVSFSEQDHDGAT----AMHFA---ASRGHTKVLSWLLLHGAEI-SQDLW 272 Query: 622 GNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 G T LH AA + +C ++L A + + G TA D+A H C L Q Sbjct: 273 GGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQ 329 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 48/128 (37%), Gaps = 11/128 (8%) Query: 555 ICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGH 614 C L V + L D P LH A ++ P++ +++ Sbjct: 180 ACQEGHLEVTKYLVQECSADPHLRAQDGMTP----LHAAAQM---GHNPVLVWLVSF-AD 231 Query: 615 LD--AKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEE 672 + + DG TA+H+AA L LL A + + + G T L A + EC + Sbjct: 232 VSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEI-SQDLWGGTPLHDAAENGELECCQ 290 Query: 673 LLEQAQAG 680 +L AG Sbjct: 291 ILAVNGAG 298 Score = 58.6 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 30/193 (15%), Positives = 62/193 (32%), Gaps = 34/193 (17%) Query: 578 PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGH-LDAKAADGNTALHYAALYNQPD 636 G ++ + A + LP + ++ + ++A+ +G T L+ A + Sbjct: 128 GGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLE 187 Query: 637 CLKLLLKG-RALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVIS 695 K L++ A + G T L A + H W++S Sbjct: 188 VTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPV-------------------LVWLVS 228 Query: 696 TEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPL 755 S SE+D + + ++ H + + L A S+D Sbjct: 229 FADVSFSEQDHDGATAMHFAASRGH-----TKVLSWLL-----LHGAEI---SQDLWGGT 275 Query: 756 PVKNSSRTLVQGC 768 P+ +++ C Sbjct: 276 PLHDAAENGELEC 288 Score = 58.2 bits (139), Expect = 2e-08, Method: Composition-based stats. Identities = 44/232 (18%), Positives = 83/232 (35%), Gaps = 36/232 (15%) Query: 548 PQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDF 607 ++ A DL + A G L + + L +H A + L + + Sbjct: 4 LEQALQAARRGDLDVLRSLHAAGL-----LGPSLRDSLDALPVHHAARS---GKLHCLRY 55 Query: 608 IIQNGG-HLDAKAADGNTALHYAALYNQPDCLKLLL-KGRALVGTVNEAGETALDIARKK 665 +++ ++A +G T H AA CL+ LL +G V + +G T L +A + Sbjct: 56 LVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARF 115 Query: 666 HHKECEE-LLEQAQA------GTFAFPLHV--------DYSWVISTEPGSDSEEDEEEKR 710 H + + LL Q A T A P+H ++ P + + Sbjct: 116 GHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGAT 175 Query: 711 CLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSR 762 L + H L+++ + S A P ++D P+ +++ Sbjct: 176 PLYLACQEGH-----LEVTKYLVQ-ECS---ADPHLRAQD--GMTPLHAAAQ 216 Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 738 SLGAATPQGES-EDCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETPE 791 SL AA G S D LPV +++R+ C R+ + + + + TP Sbjct: 21 SLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPA 75 >1BLX-B nrPDB Length = 166 Score = 70.5 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 38/83 (45%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 A++V S + +++ G + + A G + +H AA D LK+L++ A V ++ Sbjct: 45 ALQVMMFGSPAVALELLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALD 104 Query: 653 EAGETALDIARKKHHKECEELLE 675 G + +A ++ H L Sbjct: 105 STGSLPIHLAIREGHSSVVSFLA 127 Score = 61.7 bits (148), Expect = 2e-09, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 46/112 (41%), Gaps = 10/112 (8%) Query: 564 LEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGN 623 LE G + +P +H A + L + ++++G ++A + G+ Sbjct: 58 LELLKQGASPN--VQDASGTSP----VHDAART---GFLDTLKVLVEHGADVNALDSTGS 108 Query: 624 TALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 675 +H A + L + + + +G T L++AR++ + ++L+ Sbjct: 109 LPIHLAIREGHSSVVS-FLAPESDLHHRDASGLTPLELARQRGAQNLMDILQ 159 Score = 47.0 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 34/91 (37%), Gaps = 2/91 (2%) Query: 596 VANQASLPLVDFIIQNG-GHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 654 A + + V ++ H DA G TAL ++ P LLK A + + Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALELLKQGASPNVQDAS 73 Query: 655 GETALDIARKKHHKECEELLEQAQAGTFAFP 685 G + + A + + ++L + A A Sbjct: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNALD 104 >4OAU-C nrPDB Length = 699 Score = 70.5 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 29/166 (17%), Positives = 58/166 (34%), Gaps = 17/166 (10%) Query: 579 GPDAQAPEELV----LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQ 634 G D A + + +H + + + ++ +G ++ + G T L A Sbjct: 172 GADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKH 231 Query: 635 PDCLKLLLKGR-ALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHV----- 688 ++ LL+ + + G+TAL +A + K+ ELL + A T L + Sbjct: 232 LGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRN 291 Query: 689 ---DYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNK 731 V+ + + E P +HW + D+ Sbjct: 292 YDHSLVKVLLSHGAKEDFHPPAED----WKPQSSHWGAALKDLHRI 333 Score = 69.8 bits (169), Expect = 6e-12, Method: Composition-based stats. Identities = 38/220 (17%), Positives = 69/220 (31%), Gaps = 24/220 (10%) Query: 591 HLAVKVANQASLPLVDFIIQNGGHLD-AKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 HL +K + LV +++ G +++ + G T LH A ++ D ++LLL+ A Sbjct: 7 HLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPV 66 Query: 650 TVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLH-------------VDYSWVIST 696 + G T +A + +L A + V + Sbjct: 67 LRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYK 126 Query: 697 EPGSDSEE-----DEEEKRCLLKLPAQAHWASGRLDISNKTY-ETVASLGAATPQGESED 750 + + D+E R G +++ E A + A G + Sbjct: 127 RGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNAL 186 Query: 751 CPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETP 790 L SS H D ++ E +TP Sbjct: 187 IHALL----SSDDSDVEAITHLLLDHGADVNVRGERGKTP 222 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 41/246 (16%), Positives = 71/246 (28%), Gaps = 42/246 (17%) Query: 488 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPE 547 ++ L + N + GG P + +R D + R + Sbjct: 15 NEDVDLVQQLLEGGANVNFQ---EEEGGWTPLHNAVQMSREDIV-------ELLLRHGAD 64 Query: 548 PQRLWTAICNRDLLSVLEAFANGQDFG--QPLPGPDAQAPEELVLHLAVKVANQASLPLV 605 P N +L A A G D + ++ A + + Sbjct: 65 P---VLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKAL 121 Query: 606 DFIIQNGGHLD---AKAAD-------GNTALHYAALYNQPDCLKLLL-KGRALVGTVNEA 654 F+ + G +++ D G TAL AA + LK+LL + A V + Sbjct: 122 KFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNM 181 Query: 655 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLK 714 G AL LL + A + ++ + E K L+ Sbjct: 182 GRNAL----------IHALLSSDDSDVEA------ITHLLLDHGADVNVRGERGKTPLIL 225 Query: 715 LPAQAH 720 + H Sbjct: 226 AVEKKH 231 >1BD8-A nrPDB Length = 156 Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 36/83 (43%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 A++V S + +++ G + + G + +H AA D LK+L++ A V + Sbjct: 39 ALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPD 98 Query: 653 EAGETALDIARKKHHKECEELLE 675 G + +A ++ H L Sbjct: 99 GTGALPIHLAVQEGHTAVVSFLA 121 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 13/97 (13%), Positives = 35/97 (36%), Gaps = 1/97 (1%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G + A L + ++++G ++ G +H A + Sbjct: 58 GASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVV 117 Query: 639 KLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 675 L + + + G T L++A ++ ++ ++L+ Sbjct: 118 S-FLAAESDLHRRDARGLTPLELALQRGAQDLVDILQ 153 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 37/100 (37%), Gaps = 8/100 (8%) Query: 596 VANQASLPLVDFIIQNG-GHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 654 A + + V ++ H DA G TAL ++ LLK A + + Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASPNVQDTS 67 Query: 655 GETALDIARKKHHKECEELLEQAQAGTF------AFPLHV 688 G + + A + + ++L + A A P+H+ Sbjct: 68 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL 107 >3UI2-A nrPDB Length = 244 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 14/137 (10%) Query: 529 DYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL 588 ++ + Y+ A E + W + A+ Q Q L D A +E Sbjct: 30 SWVPSSYI----AADVVSEYETPWWTAARK---------ADEQALSQLLEDRDVDAVDEN 76 Query: 589 VLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGN-TALHYAALYNQPDCLKLLLKGRAL 647 + VA S V + + G LD + G TALH AA Y +P+ ++ L++ A Sbjct: 77 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGAD 136 Query: 648 VGTVNEAGETALDIARK 664 + +E G TAL++AR+ Sbjct: 137 IEVEDERGLTALELARE 153 >3DEO-A nrPDB Length = 183 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 14/137 (10%) Query: 529 DYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL 588 ++ + Y+ A E + W + A+ Q Q L D A +E Sbjct: 29 SWVPSSYI----AADVVSEYETPWWTAARK---------ADEQALSQLLEDRDVDAVDEN 75 Query: 589 VLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGN-TALHYAALYNQPDCLKLLLKGRAL 647 + VA S V + + G LD + G TALH AA Y +P+ ++ L++ A Sbjct: 76 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGAD 135 Query: 648 VGTVNEAGETALDIARK 664 + +E G TAL++AR+ Sbjct: 136 IEVEDERGLTALELARE 152 >4O1O-A nrPDB Length = 717 Score = 63.6 bits (153), Expect = 4e-10, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 51/140 (36%), Gaps = 7/140 (5%) Query: 553 TAICNRDLLSVLEAFANGQDFG-QPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQN 611 A + ++ + NG D D + + + A + + +V ++ Sbjct: 114 EAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHA 173 Query: 612 -GGHLDAKAADGNTALHYAALYNQPD----CLKLLLKGRALVGTVNEAGETALDIARKKH 666 +DA+ G AL YA L +LLL A V E +T L +A ++ Sbjct: 174 MKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERK 233 Query: 667 HKECEE-LLEQAQAGTFAFP 685 + + + LLEQ Q Sbjct: 234 NLDLVQMLLEQEQIEVNDTD 253 Score = 62.8 bits (151), Expect = 6e-10, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 67/212 (31%), Gaps = 42/212 (19%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L +A+ V +G D L + P + ++ L+ ++ Sbjct: 46 LHSAVQMDSEDLVALLLKHGADPC--LRKRNGATPF-------IIAGITGNVRLLQLLLP 96 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGT-----VNEA-----GETALD 660 N ++ +G TA AA+Y + + L+ L + A V ++ G TAL Sbjct: 97 NVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALM 156 Query: 661 IARKKHHKECEELLEQAQ---------AGTFAFPLHV---------DYSWVISTEPGSDS 702 A +K H +L A G A + + ++ + Sbjct: 157 DAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGADVN 216 Query: 703 EEDEEEKRCLLKLPAQAHWASGRLDISNKTYE 734 E K L+ + + LD+ E Sbjct: 217 VRGEGSKTPLILAVERKN-----LDLVQMLLE 243 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 35/96 (36%), Gaps = 1/96 (1%) Query: 592 LAVKVANQASLPLVDFIIQNGGHLDAKAAD-GNTALHYAALYNQPDCLKLLLKGRALVGT 650 + + +A + V +++ G + + + G + LH A + D + LLLK A Sbjct: 11 MLTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCL 70 Query: 651 VNEAGETALDIARKKHHKECEELLEQAQAGTFAFPL 686 G T IA + +LL + Sbjct: 71 RKRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDV 106 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 38/108 (35%), Gaps = 6/108 (5%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFII-QNGGHLDAKAADGNTALHYAALYNQPDC 637 G D E + + +L LV ++ Q ++ +G TAL A + Sbjct: 212 GADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELRLEEI 271 Query: 638 LKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFP 685 KLL A + IAR+ + + + L +AG P Sbjct: 272 AKLLCHRGASTNCGDLVA-----IARRNYDSDLVKFLRLHKAGEDFRP 314 >4OT9-A nrPDB Length = 359 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 68/381 (17%), Positives = 122/381 (32%), Gaps = 56/381 (14%) Query: 507 EAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEA 566 EA PS P + + + A + R QR A+ + + + A Sbjct: 13 EAAEPS--APSRTPQCEPQAPEMLQRA----REYNARLFGLAQRSARALLDYGVTADARA 66 Query: 567 FANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGH---LDAKAADGN 623 GQ + P LHLA+ + + + ++I + ++ Sbjct: 67 LLAGQRHLLTAQDENGDTP----LHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQ 122 Query: 624 TALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK--KHHKECEELLEQAQAGT 681 T LH A + Q + LL+ A ++ G++A+ +A + E L Q+ A Sbjct: 123 TPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPA 182 Query: 682 FAFPLHV-DYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLG 740 LH+ D+ + P + + LD+ ++ A + Sbjct: 183 VPQLLHMPDFEGLY---PVHLAVRARSPE---------------CLDL---LVDSGAEVE 221 Query: 741 AATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETP----ESLGSP 796 A QG + ++ G H + + A TP LG P Sbjct: 222 ATERQG------GRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYP 275 Query: 797 ASSSSLMSP--------LEPGDPSQAPPNSE-EGLREPPGTSRPSLTSGTTPSEMYLPVR 847 + L+ EP P +PP S+ + E P S G TP ++ + Sbjct: 276 TLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTK 335 Query: 848 FSSESTRSYRRGARSPEDGPS 868 + + + P PS Sbjct: 336 VKTLLLNAAQNTMEPPLTPPS 356 >1D9S-A nrPDB Length = 136 Score = 60.5 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 47/131 (35%), Gaps = 11/131 (8%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 L TA + +V + G D + P ++V S + + ++ Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRF--GRRP--------IQVMMMGSAQVAELLLL 65 Query: 611 NGGHLDAKAADGNT-ALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKE 669 +G + T +H AA D L +L + A + + G +D+A ++ H++ Sbjct: 66 HGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRD 125 Query: 670 CEELLEQAQAG 680 L A Sbjct: 126 IARYLHAATGD 136 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 31/94 (32%), Gaps = 2/94 (2%) Query: 593 AVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVN 652 A + + V +++ G +A G + + +LLL A + Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAEPNCAD 74 Query: 653 EAGET-ALDIARKKHHKECEELLEQAQAGTFAFP 685 A T + A ++ + +L +A A Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVCD 108 >6EMK-G nrPDB Length = 426 Score = 59.4 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 48/128 (37%), Gaps = 8/128 (6%) Query: 550 RLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFII 609 L A + L + G D + + +HLA+ + + ++ Sbjct: 43 SLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNT----CVHLALM---KGHEQTLHLLL 95 Query: 610 QNGGH-LDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHK 668 Q ++ + +G +H A + + CL LL+ A + ++ G+T L + + Sbjct: 96 QQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSI 155 Query: 669 ECEELLEQ 676 C ++L Sbjct: 156 SCMKMLLN 163 Score = 49.0 bits (115), Expect = 9e-06, Method: Composition-based stats. Identities = 50/298 (16%), Positives = 91/298 (30%), Gaps = 54/298 (18%) Query: 599 QASLPLVDFIIQNGGHL--DAKAADGNTALHYAALYNQPDCLKLLLKGRALVG--TVNEA 654 + +L +V +++ L + + +G ++LHYA+ + + L++ Sbjct: 15 EGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFK 74 Query: 655 GETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLK 714 G T + +A K H++ LL Q Q F + E + + Sbjct: 75 GNTCVHLALMKGHEQTLHLLLQ-QFPRF------------------INHRGENGRAPIHI 115 Query: 715 LPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASG 774 ++ L + A L G++ P+ C + Sbjct: 116 ACMNDYYQ--CLSL---LIGVGADLWVMDTNGDT-------PLHVCLEYGSISCMKMLLN 163 Query: 775 DRSEVSSLSSEAPETPESLGSPASSSSLMSPLEPGDPSQAPPNSEEGLREPPGTSRPSLT 834 E SL P++ + + L+E P L Sbjct: 164 -----------EGEV--SLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKKKG-PPLG 209 Query: 835 SGTTPSEMYLPV---RFSSESTRSYRRGARSPEDGPSARQPLP--RRNVPVGITEGDG 887 +G PS P+ + + E S SP S PLP R + T G+G Sbjct: 210 AGKKPSSFRTPILNAKATFEDGPSPVLSMNSPYSLYSNNSPLPVLPRRISTHTTSGNG 267 Score = 47.0 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 34/87 (39%), Gaps = 10/87 (11%) Query: 579 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 638 G + +AP +H+A L L +I G L +G+T LH Y C+ Sbjct: 106 GENGRAP----IHIACMNDYYQCLSL---LIGVGADLWVMDTNGDTPLHVCLEYGSISCM 158 Query: 639 KLLLKGRA---LVGTVNEAGETALDIA 662 K+LL ++ +D+A Sbjct: 159 KMLLNEGEVSLDDNVRDKGNWKPIDVA 185 >2A5E-A nrPDB Length = 156 Score = 59.4 bits (142), Expect = 7e-09, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 47/137 (34%), Gaps = 11/137 (8%) Query: 546 PEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLV 605 P L TA + V G P + P ++V S + Sbjct: 11 PSADWLATAAARGRVEEVRALLEAGALPNAPNSY--GRRP--------IQVMMMGSARVA 60 Query: 606 DFIIQNGGHLDAKAADGNT-ALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 664 + ++ +G + T +H AA D L +L + A + + G +D+A + Sbjct: 61 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 Query: 665 KHHKECEELLEQAQAGT 681 H++ L A GT Sbjct: 121 LGHRDVARYLRAAAGGT 137 >3EHQ-A nrPDB Length = 222 Score = 57.1 bits (136), Expect = 4e-08, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 53/153 (34%), Gaps = 17/153 (11%) Query: 527 RRDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPE 586 R I + YV + P L A +L + E N + Sbjct: 57 RTGLIPSNYVAEQAESIDNP----LHEAAKRGNLSWLRECLDNRVGVN---------GLD 103 Query: 587 ELVLHLAVKVANQASLPLVDFII-QNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGR 645 + + +V+ + Q L+ + G+TALH AA D ++LLL Sbjct: 104 KAGSTALYWACHGGHKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKG 163 Query: 646 ALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 A N + A D+A + C LL++ Q Sbjct: 164 ARTDLRNIEKKLAFDMAT---NAACASLLKKKQ 193 Score = 51.3 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 14/110 (12%) Query: 615 LDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELL 674 + +A + LH AA L+ L R V +++AG TAL A HK+ E+L Sbjct: 66 VAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEML 125 Query: 675 ---------EQAQAGTFAFPL-----HVDYSWVISTEPGSDSEEDEEEKR 710 +Q + G A + D ++ + + E+K Sbjct: 126 FTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKL 175 >5D68-A nrPDB Length = 486 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 39/92 (42%), Gaps = 4/92 (4%) Query: 586 EELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLL-KG 644 ++ LH + A + L+ ++ ++ +D +HYA Y + + ++LL KG Sbjct: 38 DDFPLH---RSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG 94 Query: 645 RALVGTVNEAGETALDIARKKHHKECEELLEQ 676 + +N + L A H E ++L Sbjct: 95 KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN 126 Score = 46.7 bits (109), Expect = 5e-05, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 36/87 (41%), Gaps = 5/87 (5%) Query: 596 VANQASLPLVDFIIQNG-GHLDAKAADGNTALHYAALYNQPDCLKLLLKG-RALVGTVNE 653 + +++ G + + ++ LH+AA + +++LL ++ Sbjct: 78 ACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ 137 Query: 654 AGETALDIARKKHH---KECEELLEQA 677 G + L+I + +E +LL++A Sbjct: 138 QGRSPLNICEENKQNNWEEAAKLLKEA 164 >5U0K-A nrPDB Length = 141 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 1/84 (1%) Query: 596 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKG-RALVGTVNEA 654 A + + + ++ K D TALH AA + +K L++ + + Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRW 91 Query: 655 GETALDIARKKHHKECEELLEQAQ 678 G LD A + +H E +LL+ Q Sbjct: 92 GNIPLDDAVQFNHLEVVKLLQDYQ 115 Score = 35.1 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%) Query: 626 LHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQA 677 L +AA L+ + + TAL +A + H E + L +A Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEA 80 >4BSZ-B nrPDB Length = 202 Score = 51.7 bits (122), Expect = 2e-06, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 15/133 (11%) Query: 555 ICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ---- 610 DL S+ + F + L + LH+A A + V +I++ Sbjct: 22 ARAGDLDSLKDIFTTLVSP-ELLSTCKESESDSTALHMA---AANGHIETVRYILETVSR 77 Query: 611 -NGGH-----LDAKAADGNTALHYAALYNQPDCLKLLL-KGRALVGTVNEAGETALDIAR 663 N ++ GNTALH+A+L + D +KLL + A N+ G A+ A Sbjct: 78 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAE 137 Query: 664 KKHHKECEELLEQ 676 +E E + Sbjct: 138 NSGKEEVETYFLK 150 >5UQE-A nrPDB Length = 520 Score = 51.3 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 44/116 (37%), Gaps = 6/116 (5%) Query: 564 LEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGN 623 L FA D G D + + L A A + + + ++ + D Sbjct: 397 LRHFAKKLDP--RREGGDQRVKSVINLLFA---AYTGDVSALRRFALSAMDMEQRDYDSR 451 Query: 624 TALHYAALYNQPDCLKLLLKG-RALVGTVNEAGETALDIARKKHHKECEELLEQAQ 678 TALH AA + +K LL+ + + T +D A H + ++L++ Q Sbjct: 452 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQ 507 Score = 36.3 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 44/129 (34%), Gaps = 22/129 (17%) Query: 538 HRFARRCTPEPQ----------RLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEE 587 FA++ P + L A D+ ++ + D Q Sbjct: 398 RHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQR------DYDSR 451 Query: 588 LVLHLAVKVANQASLPLVDFIIQNGGHLDA--KAADGNTALHYAALYNQPDCLKLLLKGR 645 LH+A A + + +V F+++ ++ K NT + A + D K+L + + Sbjct: 452 TALHVA---AAEGHVEVVKFLLEA-CKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQ 507 Query: 646 ALVGTVNEA 654 ++ Sbjct: 508 VQYTPQGDS 516 >6E2G-A nrPDB Length = 727 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 31/127 (24%) Query: 587 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYN 633 + LH+AV N + LV ++ G + A+A G L +AA Sbjct: 118 QTALHIAVINQN---VNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVG 174 Query: 634 QPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWV 693 + ++LL++ A + + G T L I + +K TFA + Y+ + Sbjct: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNK------------TFACQM---YNLL 219 Query: 694 ISTEPGS 700 +S + G Sbjct: 220 LSYDGGD 226 Score = 49.4 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 35/138 (25%), Positives = 54/138 (39%), Gaps = 12/138 (8%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 LW C E++A +D + + E +L A + QA + L+ F Sbjct: 15 LWNKFCR--WFHRRESWAQSRD--EQNLLQQKRIWESPLLLAAKENNVQALIKLLKF--- 67 Query: 611 NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALV--GTVNE---AGETALDIARKK 665 G + K A G TALH AALY+ + +L++ + + G+TAL IA Sbjct: 68 EGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVIN 127 Query: 666 HHKECEELLEQAQAGTFA 683 + L A A Sbjct: 128 QNVNLVRALLARGASVSA 145 Score = 45.9 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 33/178 (18%), Positives = 59/178 (33%), Gaps = 29/178 (16%) Query: 527 RRDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFA-NGQDFGQPLPGPDAQAP 585 R + ++ E ++ L A ++ ++++ G + Q A Sbjct: 26 RESWAQSR-DEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQK------GAM 78 Query: 586 EELVLHLAVKVANQASLPLVDFIIQNGGHL-----DAKAADGNTALHYAALYNQPDCLKL 640 E LH+A A +L +++ L ++ +G TALH A + + ++ Sbjct: 79 GETALHIA---ALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRA 135 Query: 641 LLKGRALVGTVNE-------------AGETALDIARKKHHKECEELLEQAQAGTFAFP 685 LL A V GE L A +E LL + A A Sbjct: 136 LLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQD 193 >2RFA-A nrPDB Length = 232 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 31/127 (24%) Query: 587 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYN 633 + LH+AV N + LV ++ G + A+A G L +AA Sbjct: 76 QTALHIAVINQN---VNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVG 132 Query: 634 QPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWV 693 + ++LL++ A + + G T L I + +K TFA + Y+ + Sbjct: 133 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNK------------TFACQM---YNLL 177 Query: 694 ISTEPGS 700 +S + G Sbjct: 178 LSYDGGD 184 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 596 VANQASLPLVDFIIQ-NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALV--GTVN 652 A + + + +++ G + + A G TALH AALY+ + +L++ + + Sbjct: 10 AAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 69 Query: 653 E---AGETALDIARKKHHKECEELLEQAQAGTFA 683 G+TAL IA + L A A Sbjct: 70 SELYEGQTALHIAVINQNVNLVRALLARGASVSA 103 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 41/120 (34%), Gaps = 21/120 (17%) Query: 584 APEELVLHLAVKVANQASLPLVDFIIQNGGHL-----DAKAADGNTALHYAALYNQPDCL 638 A E LH+A A +L +++ L ++ +G TALH A + + + Sbjct: 35 AMGETALHIA---ALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLV 91 Query: 639 KLLLKGRALVGTVNE-------------AGETALDIARKKHHKECEELLEQAQAGTFAFP 685 + LL A V GE L A +E LL + A A Sbjct: 92 RALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQD 151 Score = 40.1 bits (92), Expect = 0.005, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 1/68 (1%) Query: 624 TALHYAALYNQPDCLKLLLKG-RALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTF 682 + L AA N L LLK V GETAL IA + E +L +A Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64 Query: 683 AFPLHVDY 690 P+ + Sbjct: 65 FEPMTSEL 72 >5U0J-A nrPDB Length = 140 Score = 50.9 bits (120), Expect = 3e-06, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 34/84 (40%), Gaps = 1/84 (1%) Query: 596 VANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKG-RALVGTVNEA 654 A + + + ++ + D TALH AA + +K LL+ + + Sbjct: 31 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 90 Query: 655 GETALDIARKKHHKECEELLEQAQ 678 T +D A H + ++L++ Q Sbjct: 91 NNTPMDEALHFGHHDVFKILQEYQ 114 Score = 36.3 bits (82), Expect = 0.064, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%) Query: 626 LHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQA 677 L +AA L+ + + TAL +A + H E + L +A Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 79 Score = 35.5 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 38/107 (35%), Gaps = 12/107 (11%) Query: 550 RLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFII 609 L A D+ ++ + D Q LH+A A + + +V F++ Sbjct: 27 NLLFAAYTGDVSALRRFALSAMDMEQR------DYDSRTALHVA---AAEGHVEVVKFLL 77 Query: 610 QNGGHLDA--KAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEA 654 + ++ K NT + A + D K+L + + ++ Sbjct: 78 EA-CKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDS 123 >6DMR-A nrPDB Length = 730 Score = 50.1 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 31/134 (23%) Query: 587 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYN 633 + LH+AV N L LV ++ G + A+A G L +AA Sbjct: 118 QTALHIAVMNQN---LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVG 174 Query: 634 QPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWV 693 + ++LL++ A + + G T L I + +K TFA + Y+ + Sbjct: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNK------------TFACQM---YNLL 219 Query: 694 ISTEPGSDSEEDEE 707 +S + SD + E Sbjct: 220 LSYDEHSDHLQSLE 233 Score = 47.0 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 41/130 (31%), Gaps = 21/130 (16%) Query: 574 GQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAA-----DGNTALHY 628 Q A E LH+A A +L +++ L + A G TALH Sbjct: 67 NQSCDFQQRGAVGETALHVA---ALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHI 123 Query: 629 AALYNQPDCLKLLLKGRALVGTVNE-------------AGETALDIARKKHHKECEELLE 675 A + + ++ LL A V GE L A +E LL Sbjct: 124 AVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI 183 Query: 676 QAQAGTFAFP 685 + A A Sbjct: 184 EHGADIRAQD 193 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 35/147 (23%), Positives = 57/147 (38%), Gaps = 12/147 (8%) Query: 544 CTPEPQRLWTAICNRDLLSVLEAFANG-QDFGQPLPGPDAQAPEELVLHLAVKVANQASL 602 C P+ + W L +L ++ G QD+ Q + E + ++ A + L Sbjct: 4 CPPKAKGPWA-----QLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDL 58 Query: 603 PLVDFIIQN-GGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNE-----AGE 656 L+ ++ N + A G TALH AALY+ + LL++ + G+ Sbjct: 59 RLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQ 118 Query: 657 TALDIARKKHHKECEELLEQAQAGTFA 683 TAL IA + L A A Sbjct: 119 TALHIAVMNQNLNLVRALLARGASVSA 145 >1WG0-A nrPDB Length = 243 Score = 49.7 bits (117), Expect = 6e-06, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 42/120 (35%), Gaps = 18/120 (15%) Query: 580 PDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHL---DAKAADGNTALHYAALYNQPD 636 D + P LH +V + QA + F++ ++ D G T H A + Sbjct: 34 QDGRIP----LHWSV--SFQAH-EITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLE 86 Query: 637 CLKLLLKG--RALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT------FAFPLHV 688 +K L + + + G T L +A K E + L + A PLH Sbjct: 87 VVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHR 146 Score = 49.7 bits (117), Expect = 6e-06, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 32/92 (34%), Gaps = 2/92 (2%) Query: 585 PEELVLHLAVKVANQASLPLVDFIIQN--GGHLDAKAADGNTALHYAALYNQPDCLKLLL 642 P++ + +L +V + L+ G T LH A + + L+ Sbjct: 68 PDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLI 127 Query: 643 KGRALVGTVNEAGETALDIARKKHHKECEELL 674 + A V ++ + L A + ELL Sbjct: 128 ENGASVRIKDKFNQIPLHRAASVGSLKLIELL 159 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 32/201 (15%), Positives = 55/201 (27%), Gaps = 31/201 (15%) Query: 617 AKAADGNTALHYAALYNQPDCLKLLLKGRALVGT---VNEAGETALDIARKKHHKECEEL 673 K DG LH++ + + LL V +++G T IA + E + Sbjct: 31 QKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKS 90 Query: 674 L----------EQAQAGTFAFPLHVDYSW-----VISTEPGSDSEEDEEEKRCLLKLPAQ 718 L + G L V W + S +D+ + L + + Sbjct: 91 LYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASV 150 Query: 719 AHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSE 778 S K E + LG + +D P+ ++ A Sbjct: 151 G---------SLKLIELLCGLGKSAV--NWQDKQGWTPLFHALAEGHGDAAVLLVEKYGA 199 Query: 779 VSSLSSEAPETPE--SLGSPA 797 L E +L Sbjct: 200 EYDLVDNKGAKAEDVALNEQV 220 >5C5B-A nrPDB Length = 375 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 58/314 (18%), Positives = 131/314 (41%), Gaps = 26/314 (8%) Query: 88 LSQNSHELSTGFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQL 147 L + +S+ + E+++ L L + + FP+ + L++ K+ Sbjct: 75 LGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKE-ILTLKEVF 133 Query: 148 EKAWKDYEA---KMAKLEKERDRARVTGGIPGEVAQDMQRERRIFQLHMCEYLLKAGESQ 204 + A D++A + ++L K+R+ +V EV +D+ R+ M Y Q Sbjct: 134 QIASNDHDAAINRYSRLSKKRENDKVKY----EVTEDVYTSRKKQHQTMMHYFCALNTLQ 189 Query: 205 MKQGPDFLQSLIKFFHAQHNFFQDGWKAA-QSLFPFIEKLAASVHALHQAQEDELQKLTQ 263 K+ L+ L+ + AQ +FF+ G + + L F+ + SV + + + +++ + Q Sbjct: 190 YKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQ 249 Query: 264 LRDSLRGTLQLESREEHLSRKNSGCGYSIHQHQGNKQFGTEKVGFL--YKKSDGIRRVWQ 321 + L ++ S ++ + + N+ T K G+L K+ + W Sbjct: 250 TIEDL----EVASDPLYVPDPDPT------KFPVNRNL-TRKAGYLNARNKTGLVSSTWD 298 Query: 322 KRKCGVKYGCLTISHSTINRPPVKLTLLTCQVRP-NPEEKK-CFDLVTHN--RTYHFQAE 377 ++ + G L + + + C V + E+++ CF + + + ++ QAE Sbjct: 299 RQFYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAE 358 Query: 378 DEHECEAWVSVLQN 391 + + E W+ + N Sbjct: 359 SKKDHEEWICTINN 372 >2F37-A nrPDB Length = 251 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 24/111 (21%) Query: 571 QDFGQPLPGPDAQAPEE-----LVLHLAVKVANQASLPLVDFIIQNGGHLDAKAA----- 620 +D G P P +AQ ++ LH+A+ + SL V +++NG ++ A+A Sbjct: 75 RDSGNPQPLVNAQCTDDYYRGHSALHIAI---EKRSLQCVKLLVENGANVHARACGRFFQ 131 Query: 621 --------DGNTALHYAALYNQPDCLKLLLKG---RALVGTVNEAGETALD 660 G L AA Q D + LL+ A + + G T L Sbjct: 132 KGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLH 182 Score = 41.7 bits (96), Expect = 0.002, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 54/174 (31%), Gaps = 36/174 (20%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTVN-------------EAGETALDIARKKHH 667 G++ALH A C+KLL++ A V GE L +A Sbjct: 94 RGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQ 153 Query: 668 KECE-ELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRL 726 + LLE +P S D + L L + ++ + Sbjct: 154 WDVVSYLLENPH------------------QPASLQATDSQGNTVLHALVMISDNSAENI 195 Query: 727 DISNKTYETVASLGA---ATPQ-GESEDCPPPLPVKNSSRTLVQGCARHASGDR 776 + Y+ + GA T Q + + P+K +++ RH Sbjct: 196 ALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQRE 249 >6BOA-A nrPDB Length = 742 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 54/139 (38%), Gaps = 14/139 (10%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQ 610 LW+ C E++A +D + + E +L A + ++ +++ Sbjct: 15 LWSKFCR--WFQRRESWAQSRD--EQNLLQQKRIWESPLL----LAAKDNDVQALNKLLK 66 Query: 611 N-GGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALV--GTVNE---AGETALDIARK 664 + + A G TALH AALY+ + +L++ + + G+TAL IA Sbjct: 67 YEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVV 126 Query: 665 KHHKECEELLEQAQAGTFA 683 + L +A A Sbjct: 127 NQNMNLVRALLARRASVSA 145 Score = 45.9 bits (107), Expect = 8e-05, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 16/95 (16%) Query: 587 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAA-------------DGNTALHYAALYN 633 + LH+AV N + LV ++ + A+A G L +AA N Sbjct: 118 QTALHIAVVNQN---MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVN 174 Query: 634 QPDCLKLLLKGRALVGTVNEAGETALDIARKKHHK 668 + ++LL++ A + + G T L I + +K Sbjct: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNK 209 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 43/120 (35%), Gaps = 21/120 (17%) Query: 584 APEELVLHLAVKVANQASLPLVDFIIQNGGHL-----DAKAADGNTALHYAALYNQPDCL 638 A E LH+A A +L +++ L ++ +G TALH A + + + Sbjct: 77 AMGETALHIA---ALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLV 133 Query: 639 KLLLKGRALVGTVNE-------------AGETALDIARKKHHKECEELLEQAQAGTFAFP 685 + LL RA V GE L A + +E LL + A A Sbjct: 134 RALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQD 193 >4N5Q-A nrPDB Length = 257 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 41/119 (34%), Gaps = 15/119 (12%) Query: 557 NRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLD 616 ++++ +L AFA D + + + +I G ++ Sbjct: 67 TKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVN 126 Query: 617 AKAA--------------DGNTALHYAALYNQPDCLKLLLKG-RALVGTVNEAGETALD 660 A A G T L AA NQP+ ++LL++ + + + + G L Sbjct: 127 AHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 185 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 50/164 (30%), Gaps = 32/164 (19%) Query: 553 TAICNRDLLSVLEAFAN------GQDFGQPLPGP-DAQAPEELVLHLAVKVANQASLPLV 605 + C +L +L+ + G D L A + L A+ N + +V Sbjct: 12 SEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIV 71 Query: 606 DFIIQNGGHLDAKAAD-----------GNTALHYAALYNQPDCLKLLLKGRALVGTVNE- 653 ++ D G TAL+ A Q D +L+ A V + Sbjct: 72 RILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKG 131 Query: 654 -------------AGETALDIARKKHHKECEELLEQAQAGTFAF 684 GET L +A + E +LL + + Sbjct: 132 VFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITS 175 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 34/180 (18%), Positives = 55/180 (30%), Gaps = 31/180 (17%) Query: 519 SAESDMGTR-------RDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQ 571 + + R + I+ +++ + L AI R A G Sbjct: 64 NPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGA 123 Query: 572 DFG------QPLP--GPDAQAPEELVLHLAVKVANQASLPLVDFIIQN-GGHLDAKAADG 622 D P + E L LA A +V +++N + ++ + G Sbjct: 124 DVNAHAKGVFFNPKYQHEGFYFGETPLALA---ACTNQPEIVQLLMENEQTDITSQDSRG 180 Query: 623 NTALHYAA-----LYNQPDCLK-----LLLKGR--ALVGTVNEAGETALDIARKKHHKEC 670 N LH Q D +K +LL+ L N G T L +A K E Sbjct: 181 NNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEI 240 Score = 32.4 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 35/175 (20%), Positives = 56/175 (32%), Gaps = 21/175 (12%) Query: 491 LLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRD------YIMAKYVEHRFARRC 544 +LLA N + + A+ +A + RR I A + A+ Sbjct: 73 ILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGV 132 Query: 545 TPEPQRLWTAICNRDLLSVLEAFANGQDFGQPL---PGPDAQAPEELV---LHLAVKVAN 598 P+ + L A N + Q L D + + LH V VA Sbjct: 133 FFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAE 192 Query: 599 QASLP------LVDFIIQNGGHLDAKA---ADGNTALHYAALYNQPDCLKLLLKG 644 + D I+ G+ + + DG T L AA + + LK +L Sbjct: 193 DFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247 >5AN8-A nrPDB Length = 613 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 40/167 (23%), Positives = 60/167 (35%), Gaps = 29/167 (17%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPG---PDAQAP----EELVLHLAVKVANQASLP 603 L AI R L V NG + G Q EL L LA Sbjct: 91 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQW---D 147 Query: 604 LVDFIIQN---GGHLDAKAADGNTALHYAALY--NQPDCLKL-------LLKGRALV--- 648 +V+++++N L A+ + GNT LH + N P+ L LL+ A + Sbjct: 148 VVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLLQAGARLCPN 207 Query: 649 ----GTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYS 691 G N G T L +A K+ E + + Q + L ++ Sbjct: 208 VQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFT 254 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 55/192 (28%), Gaps = 46/192 (23%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTVN-------------EAGETALDIARKKHH 667 G++ALH A C+KLL++ A V GE L +A Sbjct: 86 RGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQ 145 Query: 668 KECEELL---------EQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQ 718 + L QAQ LH + P E L+ Sbjct: 146 WDVVNYLLENPHPAASLQAQDSLGNTVLHA-LVMIADNSP---------ENSALVVRMYD 195 Query: 719 AHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDR-- 776 +G N E + +L T P+K +++ +H Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLT------------PLKLAAKEGKIEIFKHILQREFS 243 Query: 777 SEVSSLSSEAPE 788 + SLS + E Sbjct: 244 APCQSLSRKFTE 255 >6DVZ-A nrPDB Length = 791 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 47/282 (16%), Positives = 86/282 (30%), Gaps = 53/282 (18%) Query: 553 TAICNRDLLSVLEAFAN------GQDFGQPLPGP-DAQAPEELVLHLAVKVANQASLPLV 605 + C +L +L+ + G D L A + L A+ N + +V Sbjct: 128 SEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIV 187 Query: 606 DFIIQNGGHLDAKAAD-----------GNTALHYAALYNQPDCLKLLLKGRALVGTVNE- 653 ++ D G TAL+ A Q D +L+ A V + Sbjct: 188 RILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKG 247 Query: 654 -------------AGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGS 700 GET L +A + E +LL + E Sbjct: 248 VFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME-------------------NEQTD 288 Query: 701 DSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPL-PVKN 759 + +D L L A + D + Y+ + L + + E+ L P++ Sbjct: 289 ITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMIL-LRSGNWELETMRNNDGLTPLQL 347 Query: 760 SSRTLVQGCARHASGDRSEVSSLSSEAPETPESLGSPASSSS 801 +++ ++ + L S + + + P SSS Sbjct: 348 AAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPVSSSL 389 Score = 32.4 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 35/175 (20%), Positives = 56/175 (32%), Gaps = 21/175 (12%) Query: 491 LLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRD------YIMAKYVEHRFARRC 544 +LLA N + + A+ +A + RR I A + A+ Sbjct: 189 ILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGV 248 Query: 545 TPEPQRLWTAICNRDLLSVLEAFANGQDFGQPL---PGPDAQAPEELV---LHLAVKVAN 598 P+ + L A N + Q L D + + LH V VA Sbjct: 249 FFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAE 308 Query: 599 QASLP------LVDFIIQNGGHLDAKA---ADGNTALHYAALYNQPDCLKLLLKG 644 + D I+ G+ + + DG T L AA + + LK +L Sbjct: 309 DFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 363 >3LJN-A nrPDB Length = 364 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 35/178 (19%), Positives = 59/178 (33%), Gaps = 12/178 (6%) Query: 578 PGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDC 637 P + ++ + A + V +I+ G + G TALH A + D Sbjct: 9 PKLNRIKSDDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDT 68 Query: 638 LKLLLKGRALVGTVNE--AGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVIS 695 K L A VG V+ G+ + +A + + L + P S + Sbjct: 69 AKYL----ASVGEVHSLWHGQKPIHLAVMANKTDLVVALVEGAKERGQMP----ESLLNE 120 Query: 696 TEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPP 753 + +E K C K HW G + + + LGA+ + D P Sbjct: 121 CDEREVNEIGSHVKHC--KGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETP 176 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 40/121 (33%), Gaps = 22/121 (18%) Query: 612 GGHLDAKAADGNTALHYAALYN--QPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKE 669 G H+ G TALH+ + +K+L++ A ++A ET L A + ++E Sbjct: 130 GSHVKHC--KGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNRE 187 Query: 670 CEELLEQAQAGTF-----------AFPLH-------VDYSWVISTEPGSDSEEDEEEKRC 711 +L+ LH D + + ED E Sbjct: 188 ALDLMMDTVPSKSSLRLDYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVP 247 Query: 712 L 712 L Sbjct: 248 L 248 Score = 35.9 bits (81), Expect = 0.086, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 2/81 (2%) Query: 586 EELVLHLAVKVANQASLPLV--DFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 643 +E L A++ N+ +L L+ ++ LD GN+ LH+A L N D ++ Sbjct: 173 DETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQGNSHLHWAILINWEDVAMRFVE 232 Query: 644 GRALVGTVNEAGETALDIARK 664 V + L ++ + Sbjct: 233 MGIDVNMEDNEHTVPLYLSVR 253 >5IRX-A nrPDB Length = 636 Score = 44.4 bits (103), Expect = 3e-04, Method: Composition-based stats. Identities = 40/192 (20%), Positives = 63/192 (32%), Gaps = 36/192 (18%) Query: 528 RDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFG--------QPLPG 579 + ++ A Y + + + L AI R++ V NG D + G Sbjct: 82 KQFVNASYTDSYYKGQTA-----LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKG 136 Query: 580 PDAQAPEELVLHLAVKVANQASLPLVDFIIQNG---GHLDAKAADGNTALHYAALY--NQ 634 EL L LA A L +V F++QN + A+ + GNT LH N Sbjct: 137 RPGFYFGELPLSLA---ACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNT 193 Query: 635 PDCLKL-------LLKGRALVGT-------VNEAGETALDIARKKHHKEC-EELLEQAQA 679 D K +L A + N G T L +A +L++ Sbjct: 194 VDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIH 253 Query: 680 GTFAFPLHVDYS 691 L ++ Sbjct: 254 EPECRHLSRKFT 265 Score = 39.3 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 31/113 (27%), Gaps = 31/113 (27%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTVNE--------------AGETALDIARKKH 666 G TALH A + LL++ A V GE L +A + Sbjct: 95 KGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTN 154 Query: 667 HKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQA 719 + L Q SW +P S D L L A Sbjct: 155 QLAIVKFLLQN-------------SW----QPADISARDSVGNTVLHALVEVA 190 >6OO7-A nrPDB Length = 786 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 38/167 (22%), Positives = 58/167 (34%), Gaps = 29/167 (17%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPG---PDAQAP----EELVLHLAVKVANQASLP 603 L AI R L V NG + G Q EL L LA Sbjct: 166 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQW---D 222 Query: 604 LVDFIIQNG---GHLDAKAADGNTALHY-------AALYNQPDCLKL--LLKGRALV--- 648 +V+++++N L A+ + GNT LH +A + LL+ A + Sbjct: 223 VVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARLCPN 282 Query: 649 ----GTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYS 691 G N G T L +A K+ E + + Q + L ++ Sbjct: 283 VQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFT 329 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 58/192 (30%), Gaps = 46/192 (23%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTVN-------------EAGETALDIARKKHH 667 G++ALH A C+KLL++ A V GE L +A Sbjct: 161 RGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQ 220 Query: 668 KECEELL---------EQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQ 718 + L QAQ LH + V+ + D E L+ Sbjct: 221 WDVVNYLLENPHQPASLQAQDSLGNTVLH---ALVMIAD-------DSAENSALVVRMYD 270 Query: 719 AHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDR-- 776 +G N E + +L T P+K +++ +H Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLT------------PLKLAAKEGKIEIFKHILQREFS 318 Query: 777 SEVSSLSSEAPE 788 + SLS + E Sbjct: 319 APCQSLSRKFTE 330 >6CV9-A nrPDB Length = 842 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 34/85 (40%), Gaps = 7/85 (8%) Query: 594 VKVANQASLPLVDFIIQ--NGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTV 651 + A ++P+V +++ + +++ G AL A + +LLLK L Sbjct: 14 LDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73 Query: 652 NEAGETALDIARKKHHKECEELLEQ 676 + AL +A K + E + Sbjct: 74 D-----ALLLAISKGYVRIVEAILN 93 >2NYJ-A nrPDB Length = 273 Score = 41.7 bits (96), Expect = 0.002, Method: Composition-based stats. Identities = 38/166 (22%), Positives = 56/166 (33%), Gaps = 35/166 (21%) Query: 528 RDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFG--------QPLPG 579 + ++ A Y + + + L AI R++ V NG D + G Sbjct: 87 KQFVNASYTDSYYKGQTA-----LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKG 141 Query: 580 PDAQAPEELVLHLAVKVANQASLPLVDFIIQNG---GHLDAKAADGNTALHYAALY--NQ 634 EL L LA A L +V F++QN + A+ + GNT LH N Sbjct: 142 RPGFYFGELPLSLA---ACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNT 198 Query: 635 PDCLKL-------LLKGRALVGT-------VNEAGETALDIARKKH 666 D K +L A + N G T L +A Sbjct: 199 VDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSG 244 Score = 39.3 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 31/113 (27%), Gaps = 31/113 (27%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTVNE--------------AGETALDIARKKH 666 G TALH A + LL++ A V GE L +A + Sbjct: 100 KGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTN 159 Query: 667 HKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQA 719 + L Q SW +P S D L L A Sbjct: 160 QLAIVKFLLQN-------------SW----QPADISARDSVGNTVLHALVEVA 195 >6BO5-A nrPDB Length = 695 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 41/167 (24%), Positives = 59/167 (35%), Gaps = 29/167 (17%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPE-------ELVLHLAVKVANQASLP 603 L AI R L V NG D G Q + EL L LA Sbjct: 128 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW---D 184 Query: 604 LVDFIIQNG---GHLDAKAADGNTALHYAALY--NQPDCLKL-------LLKGRALV--- 648 +V ++++N L+A + GNT LH + N P+ L LL+ A + Sbjct: 185 VVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPT 244 Query: 649 ----GTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYS 691 N G T L +A K+ E + Q + PL ++ Sbjct: 245 VQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFT 291 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 56/182 (30%), Gaps = 36/182 (19%) Query: 615 LDAKAAD----GNTALHYAALYNQPDCLKLLLKGRALV-------------GTVNEAGET 657 ++A+ D G++ALH A C+KLL++ A V GT GE Sbjct: 113 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 172 Query: 658 ALDIARKKHHKECEELLEQA---QAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLK 714 L +A + L + A A + +S E+ Sbjct: 173 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENS-------- 224 Query: 715 LPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASG 774 H G L + + TV + QG P+K +++ RH Sbjct: 225 -ALVIHMYDGLLQMGARLCPTVQLEEISNHQG-------LTPLKLAAKEGKIEIFRHILQ 276 Query: 775 DR 776 Sbjct: 277 RE 278 >5HI9-A nrPDB Length = 770 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 41/167 (24%), Positives = 59/167 (35%), Gaps = 29/167 (17%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPE-------ELVLHLAVKVANQASLP 603 L AI R L V NG D G Q + EL L LA Sbjct: 168 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW---D 224 Query: 604 LVDFIIQNG---GHLDAKAADGNTALHYAALY--NQPDCLKL-------LLKGRALV--- 648 +V ++++N L+A + GNT LH + N P+ L LL+ A + Sbjct: 225 VVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPT 284 Query: 649 ----GTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYS 691 N G T L +A K+ E + Q + PL ++ Sbjct: 285 VQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFT 331 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 56/182 (30%), Gaps = 36/182 (19%) Query: 615 LDAKAAD----GNTALHYAALYNQPDCLKLLLKGRALV-------------GTVNEAGET 657 ++A+ D G++ALH A C+KLL++ A V GT GE Sbjct: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 Query: 658 ALDIARKKHHKECEELLEQA---QAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLK 714 L +A + L + A A + +S E+ Sbjct: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENS-------- 264 Query: 715 LPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASG 774 H G L + + TV + QG P+K +++ RH Sbjct: 265 -ALVIHMYDGLLQMGARLCPTVQLEEISNHQG-------LTPLKLAAKEGKIEIFRHILQ 316 Query: 775 DR 776 Sbjct: 317 RE 318 >6DJS-A nrPDB Length = 676 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 594 VKVANQASLPLVDFIIQNGG--HLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTV 651 + A ++P+V +++ +++ G AL A + +LLLK L Sbjct: 49 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 108 Query: 652 NEAGETALDIARKKHHKECEELLEQ 676 + AL +A K + E + Sbjct: 109 D-----ALLLAISKGYVRIVEAILN 128 >6CUD-A nrPDB Length = 806 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 594 VKVANQASLPLVDFIIQNGG--HLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTV 651 + A ++P+V +++ +++ G AL A + +LLLK L Sbjct: 32 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 91 Query: 652 NEAGETALDIARKKHHKECEELLEQ 676 + AL +A K + E + Sbjct: 92 D-----ALLLAISKGYVRIVEAILN 111 >2ETB-A nrPDB Length = 256 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 56/182 (30%), Gaps = 36/182 (19%) Query: 615 LDAKAAD----GNTALHYAALYNQPDCLKLLLKGRALV-------------GTVNEAGET 657 ++A+ D G++ALH A C+KLL++ A V GT GE Sbjct: 79 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 138 Query: 658 ALDIARKKHHKECEELLEQA---QAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLK 714 L +A + L + A A + +S E+ Sbjct: 139 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENS-------- 190 Query: 715 LPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASG 774 H G L + + TV + QG P+K +++ RH Sbjct: 191 -ALVIHMYDGLLQMGARLCPTVQLEEISNHQG-------LTPLKLAAKEGKIEIFRHILQ 242 Query: 775 DR 776 Sbjct: 243 RE 244 Score = 38.2 bits (87), Expect = 0.019, Method: Composition-based stats. Identities = 38/146 (26%), Positives = 52/146 (35%), Gaps = 29/146 (19%) Query: 551 LWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPE-------ELVLHLAVKVANQASLP 603 L AI R L V NG D G Q + EL L LA Sbjct: 94 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW---D 150 Query: 604 LVDFIIQNG---GHLDAKAADGNTALHYAALY--NQPDCLKL-------LLKGRALV--- 648 +V ++++N L+A + GNT LH + N P+ L LL+ A + Sbjct: 151 VVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPT 210 Query: 649 ----GTVNEAGETALDIARKKHHKEC 670 N G T L +A K+ E Sbjct: 211 VQLEEISNHQGLTPLKLAAKEGKIEI 236 >4XD0-A nrPDB Length = 417 Score = 37.4 bits (85), Expect = 0.025, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 32/81 (39%), Gaps = 4/81 (4%) Query: 594 VKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALY----NQPDCLKLLLKGRALVG 649 + A ++ ++++++ G +++ + G T Y Y L+ L+ + Sbjct: 329 IIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLF 388 Query: 650 TVNEAGETALDIARKKHHKEC 670 + G + D RK + E Sbjct: 389 LKDNEGLSVFDYMRKNKNIEL 409 Score = 30.9 bits (68), Expect = 2.8, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 15/36 (41%) Query: 622 GNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGET 657 G + + AA + D ++ L+ + N G T Sbjct: 324 GWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTT 359 >3ODW-A nrPDB Length = 536 Score = 36.3 bits (82), Expect = 0.058, Method: Composition-based stats. Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 9/85 (10%) Query: 790 PESLGSPASSSSLMSPLEPGDPSQAPPNSEEGLREPPGTSRPSLTSGTTPSEMYLPVRFS 849 P SL SP +PLE GD S P S E L P T + T P + P R Sbjct: 92 PLSLDSPDREPGADAPLELGDSSPQGPMSLESLAPPESTDEGAETESPEPGDEGEPGRSG 151 Query: 850 SESTRSYRRGARSPEDGPSARQPLP 874 E PE+ P R+ +P Sbjct: 152 LE---------LEPEEPPGWRELVP 167 >6MHW-A nrPDB Length = 826 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 621 DGNTALHYAALYNQPDCLKLLLKG-RALVGTVNEAGETALD 660 G T L AA NQP+ ++LL++ + + + + G L Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILH 302 Score = 30.9 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 3/42 (7%) Query: 606 DFIIQNGGHLD---AKAADGNTALHYAALYNQPDCLKLLLKG 644 D I+ G+ + + DG T L AA + + LK +L Sbjct: 323 DMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364 Score = 29.3 bits (64), Expect = 7.5, Method: Composition-based stats. Identities = 36/196 (18%), Positives = 63/196 (32%), Gaps = 35/196 (17%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTVNE--------------AGETALDIARKKH 666 +G TAL+ A Q D LL+ A V + GET L +A + Sbjct: 215 EGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTN 274 Query: 667 HKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRL 726 E +LL + E + D L L A + Sbjct: 275 QPEIVQLLME-------------------HEQTDITSRDSRGNNILHALVTVAEDFKTQN 315 Query: 727 DISNKTYETVASLGAATPQGESEDCPPPL-PVKNSSRTLVQGCARHASGDRSEVSSLSSE 785 D + Y+ + L + + E+ L P++ +++ ++ + L S Sbjct: 316 DFVKRMYDMIL-LRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSL 374 Query: 786 APETPESLGSPASSSS 801 + + + P SSS Sbjct: 375 SRKFTDWAYGPVSSSL 390 >5UIL-A nrPDB Length = 405 Score = 35.1 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 31/85 (36%), Gaps = 4/85 (4%) Query: 594 VKVANQASLPLVDFIIQNGGHLDAKAADGNTALH----YAALYNQPDCLKLLLKGRALVG 649 + A ++ L+ +++ G +++ + G T Y LK+L+ + Sbjct: 316 IVAAYHGNIELIKWLVSKGANINDRNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLT 375 Query: 650 TVNEAGETALDIARKKHHKECEELL 674 + T D K +K + + Sbjct: 376 LTDYKDYTVFDYLEKSGNKNLLQYM 400 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 608 IIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGET 657 +I+ L K G + + AA + + +K L+ A + N G T Sbjct: 297 LIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKGTT 346 >6BBJ-A nrPDB Length = 868 Score = 34.7 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 35/220 (15%), Positives = 68/220 (30%), Gaps = 48/220 (21%) Query: 505 VMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVL 564 ++E+ + PK + + Y R ++ E + L + + D V+ Sbjct: 83 LLESTIYESSAPKKAPMDSLFGYETYHHHPTENRRKRKKILLEKENLNSQAPSPDPPPVI 142 Query: 565 EAFAN-----------GQDFGQPLP---GPDAQAPEE---------LVLHLAVKVANQAS 601 + F + LP + +E L A+ N Sbjct: 143 KMFNRHMLFDIVSRGSTAELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLNGGK 202 Query: 602 LPLVDFII---QNGGH----LDAKAAD----GNTALHYAALYNQPDCLKLLLKGRALVGT 650 + +I + G+ +++ D G TALH A ++LL++ A V Sbjct: 203 NDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHA 262 Query: 651 V---------NE-----AGETALDIARKKHHKECEELLEQ 676 +E GE L +A + + L + Sbjct: 263 QARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTE 302 >6C8G-A nrPDB Length = 675 Score = 34.0 bits (76), Expect = 0.34, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 14/70 (20%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTV---------NE-----AGETALDIARKKH 666 G TALH A ++LL++ A V +E GE L +A + Sbjct: 102 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 161 Query: 667 HKECEELLEQ 676 + L + Sbjct: 162 QPDIVHYLTE 171 >4H6Y-A nrPDB Length = 501 Score = 34.0 bits (76), Expect = 0.35, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 10/93 (10%) Query: 310 YKKSDGIRRVWQKRKCGVKYGCLTISHS-TINRPPVKLTLLTCQV-----RPNPEEKKCF 363 +K S+G WQK CL S N P L LL + N ++ F Sbjct: 409 FKNSNG----WQKLWVVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVF 464 Query: 364 DLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEA 396 L + Y+F+AE E+ E W+ V++++ A Sbjct: 465 KLHFKSHVYYFRAESEYTFERWMEVIRSATSSA 497 >3W9G-A nrPDB Length = 260 Score = 33.6 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 24/70 (34%), Gaps = 14/70 (20%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTV---------NE-----AGETALDIARKKH 666 G TALH A ++LL++ A V +E GE L +A + Sbjct: 92 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 151 Query: 667 HKECEELLEQ 676 L + Sbjct: 152 QPHIVHYLTE 161 Score = 31.6 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 36/99 (36%), Gaps = 22/99 (22%) Query: 587 ELVLHLAVKVANQASLPLVDFIIQNG---GHLDAKAADGNTALH-YAALYNQ-------- 634 EL L LA A +V ++ +NG L + + GNT LH A+ + Sbjct: 141 ELPLSLA---ACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFV 197 Query: 635 PDCLKLLLKGRALVGTV-------NEAGETALDIARKKH 666 LLL A + N G + L +A K Sbjct: 198 TKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTG 236 >6G1K-A nrPDB Length = 921 Score = 33.2 bits (74), Expect = 0.52, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 32/82 (39%), Gaps = 9/82 (10%) Query: 614 HLDAKAADGNTALHYAALYNQPDCLKLLLK-----GRALVGTVNEA--GETALDIARKK- 665 +++ G TAL A + ++LLL G AL+ + + G L + KK Sbjct: 62 NINCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKP 121 Query: 666 -HHKECEELLEQAQAGTFAFPL 686 K+ +L Q F + Sbjct: 122 SGEKQVPPILLDKQFSDFTPDI 143 >4DX2-A nrPDB Length = 259 Score = 32.8 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 23/70 (32%), Gaps = 14/70 (20%) Query: 621 DGNTALHYAALYNQPDCLKLLLKGRALVGTV---------NE-----AGETALDIARKKH 666 G TALH A ++LL+ A V +E GE L +A + Sbjct: 90 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 149 Query: 667 HKECEELLEQ 676 L + Sbjct: 150 QPHIVNYLTE 159 >4WPZ-A nrPDB Length = 397 Score = 32.4 bits (72), Expect = 0.86, Method: Composition-based stats. Identities = 26/66 (39%), Positives = 33/66 (50%), Gaps = 4/66 (6%) Query: 2 PEQFSVAEFLAVTAEDLSSPAGAAAFAAKMPRYRGAALAREEILEGDQAILQRIKKAVRA 61 PE F E L VT E+ +P AF A + GA LAR E+ E AIL R+ + A Sbjct: 318 PEVFEDGERLNVTREN--NPH--LAFGAGIHHCLGAQLARIELQEALGAILDRMPQVRLA 373 Query: 62 IHSSGL 67 + S L Sbjct: 374 VPESEL 379 >1WPI-A nrPDB Length = 133 Score = 32.4 bits (72), Expect = 0.93, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 23/48 (47%) Query: 338 TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAW 385 T+ R P ++L T + N + +KC L+ + ++ F E + W Sbjct: 6 TLQRQPRTISLFTNDIASNIKSQKCLQLLKGDVSHRFDVEIANRFPTW 53 >2DHJ-A nrPDB Length = 125 Score = 32.0 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 30/72 (41%), Gaps = 7/72 (9%) Query: 338 TINRPPVKLTLLTCQVRPNPEEKKC-FDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEA 396 + P+ + + + ++K F L T + FQAED + AW+ +Q S + Sbjct: 60 SEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTIQESSN-- 117 Query: 397 LSSAFLGEPSAG 408 PS+G Sbjct: 118 ----LNSGPSSG 125 >3V2G-A nrPDB Length = 271 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 16/89 (17%) Query: 20 SPAGAAAFAAKMPRYRGAALAREEILEG-------------DQAILQRIKKA---VRAIH 63 S AG AF R GAA+A+ LEG QA++ I++A AI Sbjct: 28 SLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIR 87 Query: 64 SSGLGHVENEEQYREAVESLGNSHLSQNS 92 + E+ RE VE+LG + NS Sbjct: 88 ADNRDAEAIEQAIRETVEALGGLDILVNS 116 >2J59-M nrPDB Length = 168 Score = 31.3 bits (69), Expect = 2.2, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Query: 338 TINRPPVKLTLLTCQVRPNPEEKKC-FDLVTHNRTYHFQAEDEHECEAWVSVLQNSKD 394 + P+ + + + ++K F L T + FQAED + AW+ +Q S + Sbjct: 54 SEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTIQESSN 111 >1MPH-A nrPDB Length = 106 Score = 31.3 bits (69), Expect = 2.2, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 343 PVKLTLLTCQVRPNPEEKK-CFDL-VTHNRTYHFQAEDEHECEAWVSVLQNS 392 PV L C+V + ++KK F L ++ Y FQA+D+ E W+ + ++ Sbjct: 55 PVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQAISSA 106 >1U5K-A nrPDB Length = 244 Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 435 RPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGV 467 P ++C CGA DP G L C +C+ + Sbjct: 147 IPQTARCARCGAPDPEHPDPLGGQLLCSKCAAL 179 >1RP4-A nrPDB Length = 389 Score = 30.5 bits (67), Expect = 3.8, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 14/36 (38%), Gaps = 1/36 (2%) Query: 465 SGVHRELGVRFSR-MQSLTLDLLGPSELLLALNMGN 499 SG H +G S+ + P+ L +GN Sbjct: 190 SGFHASIGTHLSKEYLNTKTGKWEPNLDLFMARIGN 225 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.128 0.353 Lambda K H 0.267 0.0394 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,905,676 Number of Sequences: 36641 Number of extensions: 1414728 Number of successful extensions: 3436 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 139 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 2869 Number of HSP's gapped (non-prelim): 361 length of query: 903 length of database: 10,336,785 effective HSP length: 106 effective length of query: 797 effective length of database: 6,452,839 effective search space: 5142912683 effective search space used: 5142912683 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)