BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q8TBE9
(248 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
4KNV-A nrPDB 495 e-141
2GFH-A nrPDB 493 e-140
2YY6-A nrPDB 56 1e-08
5OLW-A nrPDB 46 2e-05
2HSZ-A nrPDB 43 1e-04
4BX2-A nrPDB 43 1e-04
2P27-A nrPDB 42 3e-04
3KBB-A nrPDB 41 4e-04
4BKM-A nrPDB 41 6e-04
2HI0-A nrPDB 38 0.003
3NAS-A nrPDB 37 0.005
2C4N-A nrPDB 35 0.023
3PDW-A nrPDB 35 0.033
2X4D-A nrPDB 35 0.038
1TE2-A nrPDB 34 0.045
4RN3-A nrPDB 34 0.072
3L5K-A nrPDB 33 0.11
4G9B-A nrPDB 33 0.13
4GIB-A nrPDB 32 0.20
5BPD-A nrPDB 31 0.43
1PW5-A nrPDB 31 0.55
2B7N-A nrPDB 30 0.78
1RQL-A nrPDB 30 0.78
4PNH-A nrPDB 30 0.80
3HLT-A nrPDB 30 1.3
4I9G-A nrPDB 29 1.5
1CR6-A nrPDB 28 2.9
2HO4-A nrPDB 28 3.0
4Y2Y-A nrPDB 28 3.0
>4KNV-A nrPDB
Length = 241
Score = 495 bits (1275), Expect = e-141, Method: Compositional matrix adjust.
Identities = 237/239 (99%), Positives = 238/239 (99%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN
Sbjct: 1 MRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 60
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV
Sbjct: 61 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 120
Query: 126 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 185
RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV
Sbjct: 121 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 180
Query: 186 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKV 244
MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDC V
Sbjct: 181 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCLV 239
>2GFH-A nrPDB
Length = 260
Score = 493 bits (1268), Expect = e-140, Method: Compositional matrix adjust.
Identities = 233/247 (94%), Positives = 243/247 (98%)
Query: 1 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC
Sbjct: 13 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 72
Query: 61 FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE 120
FHPY+TCITD+RTSHWEEAIQETKGGA NRKLAEECYFLWKSTRLQHM LA+DVKAMLTE
Sbjct: 73 FHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMILADDVKAMLTE 132
Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
LRKEVRLLLLTNGDRQTQREKIEACACQSYFDA+V+GGEQ+EEKPAPSIFY+CC+LLGVQ
Sbjct: 133 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVIGGEQKEEKPAPSIFYHCCDLLGVQ 192
Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
PGDCVMVGDTLETDIQGGLNAGLKATVWINK+G VPL SSP+PHYMVSSVLELPALLQSI
Sbjct: 193 PGDCVMVGDTLETDIQGGLNAGLKATVWINKSGRVPLTSSPMPHYMVSSVLELPALLQSI 252
Query: 241 DCKVSMS 247
DCKVSMS
Sbjct: 253 DCKVSMS 259
>2YY6-A nrPDB
Length = 213
Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/241 (23%), Positives = 104/241 (43%), Gaps = 40/241 (16%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+R + FDLD TLID+A ++ + +K +L E ++P N
Sbjct: 1 MRVILFDLDGTLIDSA---------------------KDIALALEKTLKELGLEEYYPDN 39
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL----AEDVKAMLTEL 121
T + ++ K EE +++ L++ + ++ L L
Sbjct: 40 V------TKYIGGGVRALLEKVLKDKFREEYVEVFRKHYLENPVVYTKPYPEIPYTLEAL 93
Query: 122 R-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
+ K +L +++N + ++ ++ YFD +V G E+KP+P+ +LG +
Sbjct: 94 KSKGFKLAVVSNKLEELSKKILDILNLSGYFDLIVGGDTFGEKKPSPTPVLKTLEILGEE 153
Query: 181 PGDCVMVGDTLETDIQGGLNAGLKA--TVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
P ++VGDT + DI+ G AG K +W G V L S +P + +S +L L+
Sbjct: 154 PEKALIVGDT-DADIEAGKRAGTKTALALW----GYVKLNSQ-IPDFTLSRPSDLVKLMD 207
Query: 239 S 239
+
Sbjct: 208 N 208
>5OLW-A nrPDB
Length = 227
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 45/220 (20%)
Query: 7 RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNT 66
+AV FDLD + DTA +YH++ + + +++ + F+
Sbjct: 3 KAVLFDLDGVITDTA----------------EYHFRA-WKALAEEIGINGVDRQFN---- 41
Query: 67 CITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKA---------M 117
L+ E+++Q+ A + AEE L K ++ + +DV +
Sbjct: 42 --EQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQL 99
Query: 118 LTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
L +LR + L + + +E YFDA+ E KPAP IF + +
Sbjct: 100 LKDLRSNKIKIALASASKNGPF-LLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAV 158
Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPL 217
GV P + + + D+ Q G+ A I +G +P+
Sbjct: 159 GVAPSESIGLEDS-----QAGIQA-------IKDSGALPI 186
>2HSZ-A nrPDB
Length = 243
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 110 LAEDVKAMLTELRKEVRLL-LLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPS 168
L +VK L L+ + +L ++TN + + + A F ++ G E KP P+
Sbjct: 115 LYPNVKETLEALKAQGYILAVVTNKPTKHVQPILTAFGIDHLFSEMLGGQSLPEIKPHPA 174
Query: 169 IFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAG 202
FYY C G+ P + VGD+ + DI +AG
Sbjct: 175 PFYYLCGKFGLYPKQILFVGDS-QNDIFAAHSAG 207
>4BX2-A nrPDB
Length = 293
Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 19/115 (16%)
Query: 130 LTNGDRQTQREKIEACA-CQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVG 188
L++G R + A S A+VVG KP+P +F V P +MVG
Sbjct: 181 LSDGSRTPGTGSLAAAVETASGRQALVVG------KPSPYMFQCITEDFSVDPARTLMVG 234
Query: 189 DTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYMVSSVLEL 233
D LETDI G G+ T + G+ L+ + VPHY V S+ +L
Sbjct: 235 DRLETDILFGHRCGM--TTVLTLTGVSSLEEAQAYLTAGQRDLVPHYYVESIADL 287
>2P27-A nrPDB
Length = 306
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 19/115 (16%)
Query: 130 LTNGDRQTQREKIEACA-CQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVG 188
L++G R + A S A+VVG KP+P +F + P +MVG
Sbjct: 186 LSDGSRTPGTGSLAAAVETASGRQALVVG------KPSPYMFECITENFSIDPARTLMVG 239
Query: 189 DTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYMVSSVLEL 233
D LETDI G G+ T + G+ L+ + VPHY V S+ +L
Sbjct: 240 DRLETDILFGHRCGM--TTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADL 292
>3KBB-A nrPDB
Length = 216
Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 123 KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPG 182
K ++L L T+ ++ E++ + YFD +V G + + KP P I+ L V P
Sbjct: 99 KRIKLALATSTPQREALERLRRLDLEKYFDVMVFGDQVKNGKPDPEIYLLVLERLNVVPE 158
Query: 183 DCVMVGDTLETDIQGGLNAGLK 204
V+ D+ ++ ++ +AG++
Sbjct: 159 KVVVFEDS-KSGVEAAKSAGIE 179
>4BKM-A nrPDB
Length = 309
Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 16/121 (13%)
Query: 127 LLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREE----KPAPSIFYYCCNLLGVQPG 182
LL+ TN D + E A V QR+ KP+P +F V P
Sbjct: 185 LLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSPYMFQCITEDFSVDPA 244
Query: 183 DCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYMVSSVLE 232
+MVGD LETDI G G+ T + G+ L+ + VPHY V S+ +
Sbjct: 245 RTLMVGDRLETDILFGHRCGM--TTVLTLTGVSSLEEAQAYLTAGQRDLVPHYYVESIAD 302
Query: 233 L 233
L
Sbjct: 303 L 303
>2HI0-A nrPDB
Length = 240
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 50/227 (22%), Positives = 94/227 (41%), Gaps = 25/227 (11%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEE--AEIICDKVQVKLSKECFH 62
+ +A FD+D T++DT+ + + ++ + E V V +++ +
Sbjct: 3 KYKAAIFDMDGTILDTSADLTSALNYAFEQTGHRHDFTVEDIKNFFGSGVVVAVTRALAY 62
Query: 63 PYNTCITDL-----RTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA-EDVKA 116
+ L + EA+ +T+ NR L E + + + Q T +
Sbjct: 63 EAGSSRESLVAFGTKDEQIPEAVTQTE---VNRVL--EVFKPYYADHCQIKTGPFPGILD 117
Query: 117 MLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCN 175
++ LR K V+L +++N + + +E S FD + KPAP + C
Sbjct: 118 LMKNLRQKGVKLAVVSNKPNEAVQVLVEELFPGS-FDFALGEKSGIRRKPAPDMTSECVK 176
Query: 176 LLGVQPGDCVMVGDTLETDIQGGLNA---------GLKATVWINKNG 213
+LGV CV +GD+ E DIQ N+ G ++ ++ K+G
Sbjct: 177 VLGVPRDKCVYIGDS-EIDIQTARNSEMDEIAVNWGFRSVPFLQKHG 222
>3NAS-A nrPDB
Length = 233
Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
++AV FDLD + DTA +YH+ I +++ + ++ N
Sbjct: 2 LKAVIFDLDGVITDTA----------------EYHFLAWKHI-AEQIDIPFDRDM----N 40
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA----ED----VKAM 117
+ + E+I G AE+ + + R M ++ ED + +
Sbjct: 41 ERLKGISREESLESILIFGGAETKYTNAEKQELMHRKNRDYQMLISKLTPEDLLPGIGRL 100
Query: 118 LTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
L +L+ E + L + R + + A F A+V + KP P IF +L
Sbjct: 101 LCQLKNENIKIGLASSSRNAPK-ILRRLAIIDDFHAIVDPTTLAKGKPDPDIFLTAAAML 159
Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKA 205
V P DC + D E I +AG+ A
Sbjct: 160 DVSPADCAAIEDA-EAGISAIKSAGMFA 186
>2C4N-A nrPDB
Length = 250
Score = 35.4 bits (80), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINK-NGIVPLKSSPV 222
KP+P I N + + V+VGD L TDI G AGL+ + ++ + + + S P
Sbjct: 176 KPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSSLDDIDSMPF 235
Query: 223 -PHYMVSSVLEL 233
P ++ SV E+
Sbjct: 236 RPSWIYPSVAEI 247
>3PDW-A nrPDB
Length = 266
Score = 35.0 bits (79), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 16/40 (40%), Positives = 21/40 (52%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
KP I +LG + +MVGD TDI G+NAG+
Sbjct: 183 KPESIIMEQAMRVLGTDVSETLMVGDNYATDIMAGINAGM 222
>2X4D-A nrPDB
Length = 271
Score = 34.7 bits (78), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 22/42 (52%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
KP+P F +GV+ VM+GD + D+ G G++A
Sbjct: 190 KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRA 231
>1TE2-A nrPDB
Length = 226
Score = 34.3 bits (77), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 33/195 (16%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
++ A FD+D LID+ R L+V+ L + E + D + +++
Sbjct: 8 QILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNE---LPDTLGLRI-------- 56
Query: 65 NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
D+ W ++ G + +++ E + ++L E+ + +L +R+
Sbjct: 57 -----DMVVDLWYA--RQPWNGPSRQEVVERVIA-------RAISLVEETRPLLPGVREA 102
Query: 125 VRL-----LL--LTNGDRQTQREKI-EACACQSYFDAVVVGGEQREEKPAPSIFYYCCNL 176
V L LL L + EK+ + FDA+ + KP P ++ C
Sbjct: 103 VALCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK 162
Query: 177 LGVQPGDCVMVGDTL 191
LGV P CV + D++
Sbjct: 163 LGVDPLTCVALEDSV 177
>4RN3-A nrPDB
Length = 213
Score = 33.9 bits (76), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 42/204 (20%), Positives = 78/204 (38%), Gaps = 23/204 (11%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
++AV +D D + D+ A+ +++++ ++ E + + ++E +
Sbjct: 11 IKAVIYDCDGVMFDSFEANLAFYQRIMEMMGRPRLSRDNEEQM-RILHTYANREVLAHFF 69
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
D WEEA++ G R+L + M + E + L L+ V
Sbjct: 70 PSPGD-----WEEAVR-CAGAIDYREL------------VPLMIMEEGFREALDTLKGRV 111
Query: 126 RLLLLTNGDRQTQREKI-EACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDC 184
L + TN R T + + + SYF V+ KP P G+ P +
Sbjct: 112 GLGVCTN--RSTSMDMVLRLFSLDSYFSIVMTASRVTNPKPHPEPLLKVLEHFGIGPREA 169
Query: 185 VMVGDTLETDIQGGLNAGLKATVW 208
+ VGD+ E D AG+ +
Sbjct: 170 LFVGDS-EVDRLSAEAAGVPFVAY 192
>3L5K-A nrPDB
Length = 250
Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 55/228 (24%), Positives = 87/228 (38%), Gaps = 58/228 (25%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK-----------EEAEIICDKVQV 54
V + FD+D L+DT E+ KY + E A+II D +Q+
Sbjct: 30 VTHLIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKALEAAQIIIDVLQL 89
Query: 55 KLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDV 114
+SK EE ++E++ KL E ++ + L M AE
Sbjct: 90 PMSK------------------EELVEESQ-----TKLKE----VFPTAAL--MPGAE-- 118
Query: 115 KAMLTELRKE-VRLLLLTNG-----DRQTQREKIEACACQSYFDAVVVGG--EQREEKPA 166
++ LRK + L T+ D +T R K S F +V+G E + KP
Sbjct: 119 -KLIIHLRKHGIPFALATSSRSASFDMKTSRHK----EFFSLFSHIVLGDDPEVQHGKPD 173
Query: 167 PSIFYYCCNLLGVQPG--DCVMVGDTLETDIQGGLNAGLKATVWINKN 212
P IF C P C++ D ++ L AG++ + + N
Sbjct: 174 PDIFLACAKRFSPPPAMEKCLVFEDA-PNGVEAALAAGMQVVMVPDGN 220
>4G9B-A nrPDB
Length = 243
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 47/238 (19%), Positives = 89/238 (37%), Gaps = 43/238 (18%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
+++ V FDLD + DTA H++ +I + + + + + +
Sbjct: 4 KLQGVIFDLDGVITDTA----------------HLHFQAWQQIAAE-IGISIDAQ----F 42
Query: 65 NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAE-DVKAMLTELRK 123
N + + I + G + E ++ L +L E V A+L +R
Sbjct: 43 NESLKGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPGIRS 102
Query: 124 ---EVRLLLLTNGDRQTQREK---IEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
++R ++ G + A + +F + + KP P IF C L
Sbjct: 103 LLADLRAQQISVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL 162
Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPA 235
GV P C+ + D Q G++A IN +G ++S + + + L LP+
Sbjct: 163 GVPPQACIGI-----EDAQAGIDA-------INASG---MRSVGIGAGLTGAQLLLPS 205
>4GIB-A nrPDB
Length = 250
Score = 32.3 bits (72), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 13/40 (32%), Positives = 19/40 (47%)
Query: 151 FDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDT 190
FD + G+ + KP P IF L V P +C+ + D
Sbjct: 157 FDFIADAGKCKNNKPHPEIFLMSAKGLNVNPQNCIGIEDA 196
>5BPD-A nrPDB
Length = 264
Score = 31.2 bits (69), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 27/55 (49%)
Query: 182 GDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPAL 236
D + LE DI ++ G+K + + KN + LK+S + Y LEL AL
Sbjct: 153 ADDGFIAVNLEDDIIKAVDRGVKTKILLTKNLLPRLKASKIIDYAKEGKLELRAL 207
>1PW5-A nrPDB
Length = 253
Score = 30.8 bits (68), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 16/40 (40%), Positives = 20/40 (50%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
KP P + GV MVGD L TD++ G NAG+
Sbjct: 183 KPNPLVVDVISEKFGVPKERMAMVGDRLYTDVKLGKNAGI 222
>2B7N-A nrPDB
Length = 273
Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 85 GGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
GGA+N +L + + K T L+H+ +D+K+ LT RK +
Sbjct: 142 GGASNHRLGLDDALMLKDTHLRHV---KDLKSFLTHARKNL 179
>1RQL-A nrPDB
Length = 267
Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 4/133 (3%)
Query: 74 SHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE-VRLLLLTN 132
S W ++ A +++ EE + + ++ + VK ++ LR+ +++ T
Sbjct: 68 SEWNRVFRQLPTEADIQEMYEEFEEILFAILPRYASPINAVKEVIASLRERGIKIGSTTG 127
Query: 133 GDRQTQREKIEACACQSYF-DAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD-CVMVGDT 190
R+ + A Q Y D +V + +P P + Y LGV P + + VGDT
Sbjct: 128 YTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELGVYPMNHMIKVGDT 187
Query: 191 LETDIQGGLNAGL 203
+ +D++ G NAG+
Sbjct: 188 V-SDMKEGRNAGM 199
>4PNH-A nrPDB
Length = 199
Score = 30.4 bits (67), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 163 EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPV 222
KP P + + P D +VGD+L D+Q G G + + + G L + +
Sbjct: 118 RKPMPGMMKLIAERFEIDPADTPVVGDSLR-DLQAGAALGFRPHLVLTGKGKKTLAAGGL 176
Query: 223 P 223
P
Sbjct: 177 P 177
>3HLT-A nrPDB
Length = 266
Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 6/51 (11%)
Query: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
A VVG KP + F G +P + VM+GD D+ G + G+
Sbjct: 174 ATVVG------KPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGM 218
>4I9G-A nrPDB
Length = 361
Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 8/45 (17%)
Query: 164 KPAPSIFYYCCNLLGVQPGD---CVMVGDTLETDIQGGLNAGLKA 205
KPAP++ V GD ++VGD L+TDI+G AGL +
Sbjct: 194 KPAPALMTEA-----VARGDFRAALVVGDRLDTDIEGANAAGLPS 233
>1CR6-A nrPDB
Length = 554
Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 14/60 (23%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 130 LTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGD 189
L +GD++ ++ C +FD ++ + KP P I+ + + L +P + V + D
Sbjct: 127 LDDGDKRDSLAQM-MCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDD 185
>2HO4-A nrPDB
Length = 259
Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 6/51 (11%)
Query: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
A+VVG KP + F P + VM+GD D+ G N G+
Sbjct: 174 AMVVG------KPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGM 218
>4Y2Y-A nrPDB
Length = 561
Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 114 VKAMLTELRKEVRLLLLTNG--DRQTQREKIEACACQ--SYFDAVVVGGEQREEKPAPSI 169
++A L +K +LTN D + +R+ + C+ +FD ++ + KP P I
Sbjct: 106 LQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQI 165
Query: 170 FYYCCNLLGVQPGDCVMVGD 189
+ + + L P + V + D
Sbjct: 166 YKFLLDTLKASPSEVVFLDD 185
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
2GFH-A nrPDB 381 e-106
4KNV-A nrPDB 372 e-104
2YY6-A nrPDB 204 2e-53
5OLW-A nrPDB 168 2e-42
4BKM-A nrPDB 127 6e-30
2HSZ-A nrPDB 124 5e-29
4BX2-A nrPDB 110 6e-25
2P27-A nrPDB 107 4e-24
3KBB-A nrPDB 101 4e-22
Sequences not found previously or not previously below threshold:
3NAS-A nrPDB 93 2e-19
4G9B-A nrPDB 88 2e-18
4GIB-A nrPDB 82 2e-16
1RQL-A nrPDB 73 1e-13
4RN3-A nrPDB 69 2e-12
2HDO-A nrPDB 65 2e-11
2HI0-A nrPDB 63 9e-11
1TE2-A nrPDB 62 3e-10
3L5K-A nrPDB 58 5e-09
2C4N-A nrPDB 53 9e-08
2X4D-A nrPDB 53 1e-07
3QUB-A nrPDB 52 2e-07
1PW5-A nrPDB 51 4e-07
3PDW-A nrPDB 50 8e-07
3NUQ-A nrPDB 48 3e-06
4Y2Y-A nrPDB 47 9e-06
4PNH-A nrPDB 45 3e-05
2B0C-A nrPDB 44 4e-05
1CR6-A nrPDB 43 9e-05
4JB3-A nrPDB 43 2e-04
3L8F-A nrPDB 43 2e-04
3L1U-A nrPDB 43 2e-04
2O2X-A nrPDB 41 7e-04
4I9G-A nrPDB 38 0.003
2HO4-A nrPDB 37 0.010
3L8H-A nrPDB 36 0.011
1U7O-A nrPDB 36 0.015
3HLT-A nrPDB 36 0.016
2QLT-A nrPDB 35 0.030
5YA1-A nrPDB 33 0.14
3IRU-A nrPDB 32 0.21
6GRI-C nrPDB 30 0.91
2WM8-A nrPDB 30 1.2
1PZ1-A nrPDB 29 1.5
3WDH-A nrPDB 28 4.0
5MSN-A nrPDB 28 4.1
5OKI-C nrPDB 28 4.9
2LEF-A nrPDB 27 7.7
>2GFH-A nrPDB
Length = 260
Score = 381 bits (979), Expect = e-106, Method: Composition-based stats.
Identities = 233/247 (94%), Positives = 243/247 (98%)
Query: 1 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC
Sbjct: 13 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 72
Query: 61 FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE 120
FHPY+TCITD+RTSHWEEAIQETKGGA NRKLAEECYFLWKSTRLQHM LA+DVKAMLTE
Sbjct: 73 FHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMILADDVKAMLTE 132
Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
LRKEVRLLLLTNGDRQTQREKIEACACQSYFDA+V+GGEQ+EEKPAPSIFY+CC+LLGVQ
Sbjct: 133 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVIGGEQKEEKPAPSIFYHCCDLLGVQ 192
Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
PGDCVMVGDTLETDIQGGLNAGLKATVWINK+G VPL SSP+PHYMVSSVLELPALLQSI
Sbjct: 193 PGDCVMVGDTLETDIQGGLNAGLKATVWINKSGRVPLTSSPMPHYMVSSVLELPALLQSI 252
Query: 241 DCKVSMS 247
DCKVSMS
Sbjct: 253 DCKVSMS 259
>4KNV-A nrPDB
Length = 241
Score = 372 bits (954), Expect = e-104, Method: Composition-based stats.
Identities = 237/239 (99%), Positives = 238/239 (99%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN
Sbjct: 1 MRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 60
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV
Sbjct: 61 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 120
Query: 126 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 185
RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV
Sbjct: 121 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 180
Query: 186 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKV 244
MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDC V
Sbjct: 181 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCLV 239
>2YY6-A nrPDB
Length = 213
Score = 204 bits (519), Expect = 2e-53, Method: Composition-based stats.
Identities = 55/239 (23%), Positives = 103/239 (43%), Gaps = 36/239 (15%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+R + FDLD TLID+A ++ + +K +L E ++P N
Sbjct: 1 MRVILFDLDGTLIDSA---------------------KDIALALEKTLKELGLEEYYPDN 39
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA----EDVKAMLTEL 121
T + ++ K EE +++ L++ + ++ L L
Sbjct: 40 V------TKYIGGGVRALLEKVLKDKFREEYVEVFRKHYLENPVVYTKPYPEIPYTLEAL 93
Query: 122 R-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
+ K +L +++N + ++ ++ YFD +V G E+KP+P+ +LG +
Sbjct: 94 KSKGFKLAVVSNKLEELSKKILDILNLSGYFDLIVGGDTFGEKKPSPTPVLKTLEILGEE 153
Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQS 239
P ++VGDT + DI+ G AG K + G V L S +P + +S +L L+ +
Sbjct: 154 PEKALIVGDT-DADIEAGKRAGTKTA--LALWGYVKLNS-QIPDFTLSRPSDLVKLMDN 208
>5OLW-A nrPDB
Length = 227
Score = 168 bits (425), Expect = 2e-42, Method: Composition-based stats.
Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 45/220 (20%)
Query: 7 RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNT 66
+AV FDLD + DTA +YH++ + + +++ + F+
Sbjct: 3 KAVLFDLDGVITDTA----------------EYHFRA-WKALAEEIGINGVDRQFN---- 41
Query: 67 CITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKA---------M 117
L+ E+++Q+ A + AEE L K ++ + +DV +
Sbjct: 42 --EQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQL 99
Query: 118 LTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
L +LR + L + + +E YFDA+ E KPAP IF + +
Sbjct: 100 LKDLRSNKIKIALASASKNGPF-LLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAV 158
Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPL 217
GV P + + + D+ Q G+ A I +G +P+
Sbjct: 159 GVAPSESIGLEDS-----QAGIQA-------IKDSGALPI 186
>4BKM-A nrPDB
Length = 309
Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats.
Identities = 42/150 (28%), Positives = 61/150 (40%), Gaps = 20/150 (13%)
Query: 104 RLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQRE- 162
+M L + V+ L++ LL+ TN D + E A V QR+
Sbjct: 166 HFSYMKLTKAVRY----LQQPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQA 221
Query: 163 ---EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKS 219
KP+P +F V P +MVGD LETDI G G+ T + G+ L+
Sbjct: 222 DIIGKPSPYMFQCITEDFSVDPARTLMVGDRLETDILFGHRCGM--TTVLTLTGVSSLEE 279
Query: 220 SP----------VPHYMVSSVLELPALLQS 239
+ VPHY V S+ +L L+
Sbjct: 280 AQAYLTAGQRDLVPHYYVESIADLMEGLED 309
>2HSZ-A nrPDB
Length = 243
Score = 124 bits (310), Expect = 5e-29, Method: Composition-based stats.
Identities = 45/254 (17%), Positives = 89/254 (35%), Gaps = 46/254 (18%)
Query: 2 GLSRVRAVFFDLDNTLIDT---AGASRRGMLEVIKLLQSKYHYKEEA------------- 45
G+++ + + FDLD TL+++ S L+ + L Q+ +
Sbjct: 19 GMTQFKLIGFDLDGTLVNSLPDLALSINSALKDVNLPQASENLVMTWIGNGADVLSQRAV 78
Query: 46 EIICDKVQVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRL 105
+ C + + +L+++ F + + F +
Sbjct: 79 DWACKQAEKELTEDEF----------------------------KYFKRQFGFYYGENLC 110
Query: 106 QHMTLAEDVKAMLTELRKEVR-LLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEK 164
L +VK L L+ + L ++TN + + + A F ++ G E K
Sbjct: 111 NISRLYPNVKETLEALKAQGYILAVVTNKPTKHVQPILTAFGIDHLFSEMLGGQSLPEIK 170
Query: 165 PAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPH 224
P P+ FYY C G+ P + VGD+ + DI +AG + P
Sbjct: 171 PHPAPFYYLCGKFGLYPKQILFVGDS-QNDIFAAHSAGCAVVGLTYGYNYNIPIAQSKPD 229
Query: 225 YMVSSVLELPALLQ 238
++ ++ + Q
Sbjct: 230 WIFDDFADILKITQ 243
>4BX2-A nrPDB
Length = 293
Score = 110 bits (274), Expect = 6e-25, Method: Composition-based stats.
Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 16/133 (12%)
Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQRE----EKPAPSIFYYCCNL 176
LR LL+ T+ D A V R+ KP+P +F
Sbjct: 163 LRDPDCLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFQCITED 222
Query: 177 LGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYM 226
V P +MVGD LETDI G G+ T + G+ L+ + VPHY
Sbjct: 223 FSVDPARTLMVGDRLETDILFGHRCGM--TTVLTLTGVSSLEEAQAYLTAGQRDLVPHYY 280
Query: 227 VSSVLELPALLQS 239
V S+ +L L+
Sbjct: 281 VESIADLMEGLED 293
>2P27-A nrPDB
Length = 306
Score = 107 bits (267), Expect = 4e-24, Method: Composition-based stats.
Identities = 38/150 (25%), Positives = 58/150 (38%), Gaps = 17/150 (11%)
Query: 104 RLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQRE- 162
+H + A+ ++ LR LL+ T+ D A V R+
Sbjct: 152 YDEHFSFAK-LREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQA 210
Query: 163 ---EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKS 219
KP+P +F + P +MVGD LETDI G G+ T + G+ L+
Sbjct: 211 LVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGM--TTVLTLTGVSRLEE 268
Query: 220 SP----------VPHYMVSSVLELPALLQS 239
+ VPHY V S+ +L L+
Sbjct: 269 AQAYLAAGQHDLVPHYYVESIADLTEGLED 298
>3KBB-A nrPDB
Length = 216
Score = 101 bits (250), Expect = 4e-22, Method: Composition-based stats.
Identities = 44/211 (20%), Positives = 84/211 (39%), Gaps = 44/211 (20%)
Query: 6 VRAVFFDLDNTLIDTAG----ASRRGMLEVIKLLQSKYHYK-------EEAEIICDKVQV 54
+ AV FD+D L+DT A RR K H + E I+ + +++
Sbjct: 1 MEAVIFDMDGVLMDTEPLYFEAYRRVAESYGKPYTEDLHRRIMGVPEREGLPILMEALEI 60
Query: 55 KLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDV 114
K S E F +++ EE ++ ++ V
Sbjct: 61 KDSLENF---------------------------KKRVHEEKKRVFSELLKEN----PGV 89
Query: 115 KAMLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYC 173
+ L ++ K ++L L T+ ++ E++ + YFD +V G + + KP P I+
Sbjct: 90 REALEFVKSKRIKLALATSTPQREALERLRRLDLEKYFDVMVFGDQVKNGKPDPEIYLLV 149
Query: 174 CNLLGVQPGDCVMVGDTLETDIQGGLNAGLK 204
L V P V+ D+ ++ ++ +AG++
Sbjct: 150 LERLNVVPEKVVVFEDS-KSGVEAAKSAGIE 179
>3NAS-A nrPDB
Length = 233
Score = 92.6 bits (228), Expect = 2e-19, Method: Composition-based stats.
Identities = 46/211 (21%), Positives = 76/211 (36%), Gaps = 37/211 (17%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
++AV FDLD + DTA +YH+ + I +++ +
Sbjct: 2 LKAVIFDLDGVITDTA----------------EYHFLA-WKHIAEQIDIPF-------DR 37
Query: 66 TCITDLRTSHWEEAIQETK--GGAANRKLAEECYFLWKSTRLQHMTLA---------EDV 114
L+ EE+++ GGA + E L + L +
Sbjct: 38 DMNERLKGISREESLESILIFGGAETKYTNAEKQELMHRKNRDYQMLISKLTPEDLLPGI 97
Query: 115 KAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCC 174
+L +L+ E + L + R + + A F A+V + KP P IF
Sbjct: 98 GRLLCQLKNENIKIGLASSSRNAP-KILRRLAIIDDFHAIVDPTTLAKGKPDPDIFLTAA 156
Query: 175 NLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
+L V P DC + D E I +AG+ A
Sbjct: 157 AMLDVSPADCAAIEDA-EAGISAIKSAGMFA 186
>4G9B-A nrPDB
Length = 243
Score = 88.4 bits (217), Expect = 2e-18, Method: Composition-based stats.
Identities = 38/212 (17%), Positives = 80/212 (37%), Gaps = 37/212 (17%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
+++ V FDLD + DTA H++ + I ++ + + F+
Sbjct: 4 KLQGVIFDLDGVITDTA----------------HLHFQA-WQQIAAEIGISI-DAQFN-- 43
Query: 65 NTCITDLRTSHWEEAIQETK--GGAANRKLAEECYFLWKSTRLQHM---------TLAED 113
L+ +E+++ GG ++E L L ++ +
Sbjct: 44 ----ESLKGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPG 99
Query: 114 VKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYC 173
++++L +LR + + L + + A + +F + + KP P IF
Sbjct: 100 IRSLLADLRAQQISVGLASVSLNAPT-ILAALELREFFTFCADASQLKNSKPDPEIFLAA 158
Query: 174 CNLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
C LGV P C+ + D + I +G+++
Sbjct: 159 CAGLGVPPQACIGIEDA-QAGIDAINASGMRS 189
>4GIB-A nrPDB
Length = 250
Score = 82.2 bits (201), Expect = 2e-16, Method: Composition-based stats.
Identities = 35/209 (16%), Positives = 71/209 (33%), Gaps = 37/209 (17%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+ A FDLD + DTA YHY + KV + +
Sbjct: 26 IEAFIFDLDGVITDTAY----------------YHYMA-WRKLAHKVGIDI-------DT 61
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKL--AEECYFLWKSTRLQHMTLAEDV--------- 114
L+ E++ + EE + + +++L +++
Sbjct: 62 KFNESLKGISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGI 121
Query: 115 KAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCC 174
+++L +++ + L++ + + FD + G+ + KP P IF
Sbjct: 122 ESLLIDVKSNNIKIGLSSASKN-AINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSA 180
Query: 175 NLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
L V P +C+ + D I +A +
Sbjct: 181 KGLNVNPQNCIGIEDA-SAGIDAINSANM 208
>1RQL-A nrPDB
Length = 267
Score = 73.0 bits (177), Expect = 1e-13, Method: Composition-based stats.
Identities = 51/268 (19%), Positives = 100/268 (37%), Gaps = 35/268 (13%)
Query: 1 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
M ++ AV FD T +D G +++ +H K I ++ + +
Sbjct: 1 MDRMKIEAVIFDWAGTTVD------YGCFAPLEVFMEIFH-KRGVAITAEEARKPMGLLK 53
Query: 61 FHPYNTCITDLR-TSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLT 119
R S W ++ A +++ EE + + ++ + VK ++
Sbjct: 54 IDHVRALTEMPRIASEWNRVFRQLPTEADIQEMYEEFEEILFAILPRYASPINAVKEVIA 113
Query: 120 ELRKEVRLLLLTNGDRQTQREKIEA-CACQSYF-DAVVVGGEQREEKPAPSIFYYCCNLL 177
LR+ + T G + + + A Q Y D +V + +P P + Y L
Sbjct: 114 SLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMEL 173
Query: 178 GVQP-GDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPV-------------- 222
GV P + VGDT+ +D++ G NAG+ I + + L V
Sbjct: 174 GVYPMNHMIKVGDTV-SDMKEGRNAGMWTVGVILGSSELGLTEEEVENMDSVELREKIEV 232
Query: 223 ---------PHYMVSSVLELPALLQSID 241
H+ + ++ EL ++++ I+
Sbjct: 233 VRNRFVENGAHFTIETMQELESVMEHIE 260
>4RN3-A nrPDB
Length = 213
Score = 68.7 bits (166), Expect = 2e-12, Method: Composition-based stats.
Identities = 42/200 (21%), Positives = 71/200 (35%), Gaps = 25/200 (12%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK--EEAEIICDKVQVKLSKECFHP 63
++AV +D D + D+ A+ +++++ + EE I + F P
Sbjct: 11 IKAVIYDCDGVMFDSFEANLAFYQRIMEMMGRPRLSRDNEEQMRILHTYANREVLAHFFP 70
Query: 64 YNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRK 123
WEEA++ G R+L + M + E + L L+
Sbjct: 71 SPGD--------WEEAVR-CAGAIDYREL------------VPLMIMEEGFREALDTLKG 109
Query: 124 EVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
V L + TN + + SYF V+ KP P G+ P +
Sbjct: 110 RVGLGVCTNRSTSMDM-VLRLFSLDSYFSIVMTASRVTNPKPHPEPLLKVLEHFGIGPRE 168
Query: 184 CVMVGDTLETDIQGGLNAGL 203
+ VGD+ E D AG+
Sbjct: 169 ALFVGDS-EVDRLSAEAAGV 187
>2HDO-A nrPDB
Length = 209
Score = 65.3 bits (157), Expect = 2e-11, Method: Composition-based stats.
Identities = 34/235 (14%), Positives = 79/235 (33%), Gaps = 33/235 (14%)
Query: 7 RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKY---HYKEEAEIICDKVQVKLSKECFHP 63
+A+ FD+D TL ++ A M EV+ + ++ + ++ +L
Sbjct: 5 QALMFDIDGTLTNSQPAYTTVMREVLATYGKPFSPAQAQKTFPMAAEQAMTELG------ 58
Query: 64 YNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRK 123
+ + + S Q + L + ++ +L
Sbjct: 59 --------------------IAASEFDHFQAQYEDVMASHYDQ-IELYPGITSLFEQLPS 97
Query: 124 EVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
E+RL ++T+ R + + + + + KP P + V P +
Sbjct: 98 ELRLGIVTSQRRNELESGMRSYPFMMRMAVTISADDTPKRKPDPLPLLTALEKVNVAPQN 157
Query: 184 CVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
+ +GD++ +D Q A + + + G+ P + L++ L +
Sbjct: 158 ALFIGDSV-SDEQTAQAANVDFGLAV--WGMDPNADHQKVAHRFQKPLDILELFK 209
>2HI0-A nrPDB
Length = 240
Score = 63.3 bits (152), Expect = 9e-11, Method: Composition-based stats.
Identities = 43/213 (20%), Positives = 84/213 (39%), Gaps = 16/213 (7%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK-EEAE-IICDKVQVKLSKECFH 62
+ +A FD+D T++DT+ + + ++ + E+ + V V +++ +
Sbjct: 3 KYKAAIFDMDGTILDTSADLTSALNYAFEQTGHRHDFTVEDIKNFFGSGVVVAVTRALAY 62
Query: 63 PYNTCITDLR--TSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL----AEDVKA 116
+ L + E+ + NR L ++K H + +
Sbjct: 63 EAGSSRESLVAFGTKDEQIPEAVTQTEVNRVL-----EVFKPYYADHCQIKTGPFPGILD 117
Query: 117 MLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCN 175
++ LR K V+L +++N + + +E FD + KPAP + C
Sbjct: 118 LMKNLRQKGVKLAVVSNKPNEAVQVLVEEL-FPGSFDFALGEKSGIRRKPAPDMTSECVK 176
Query: 176 LLGVQPGDCVMVGDTLETDIQGGLNAGLKATVW 208
+LGV CV +GD+ E DIQ N+ +
Sbjct: 177 VLGVPRDKCVYIGDS-EIDIQTARNSEMDEIAV 208
>1TE2-A nrPDB
Length = 226
Score = 61.8 bits (148), Expect = 3e-10, Method: Composition-based stats.
Identities = 39/205 (19%), Positives = 77/205 (37%), Gaps = 20/205 (9%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
++ A FD+D LID+ R L+V+ L + E +++ + + ++
Sbjct: 8 QILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNELPDTL-GLRIDMVVDLWY-- 64
Query: 65 NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
+E ++ A + L EE L V+ + +++
Sbjct: 65 --ARQPWNGPSRQEVVERVIARAIS--LVEETR-----------PLLPGVREAVALCKEQ 109
Query: 125 VRLLLLTNGDRQTQREK-IEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
L+ L + EK + + FDA+ + KP P ++ C LGV P
Sbjct: 110 GLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAKLGVDPLT 169
Query: 184 CVMVGDTLETDIQGGLNAGLKATVW 208
CV + D++ + A +++ V
Sbjct: 170 CVALEDSV-NGMIASKAARMRSIVV 193
>3L5K-A nrPDB
Length = 250
Score = 57.6 bits (137), Expect = 5e-09, Method: Composition-based stats.
Identities = 38/209 (18%), Positives = 66/209 (31%), Gaps = 34/209 (16%)
Query: 9 VFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCI 68
+ FD+D L+DT E+ KY + ++ ++ K
Sbjct: 33 LIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKAL--------------- 77
Query: 69 TDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQ---HMTLAEDVKAMLTELRKEV 125
EA Q EE ++ + L + ++ LRK
Sbjct: 78 ---------EAAQIIIDVLQLPMSKEELVEESQTKLKEVFPTAALMPGAEKLIIHLRKHG 128
Query: 126 RLLLLTNGDRQTQREKIEACACQ--SYFDAVVVGG--EQREEKPAPSIFYYCCNLLGVQP 181
L R + + + S F +V+G E + KP P IF C P
Sbjct: 129 IPFALATSSRSASFDMKTSRHKEFFSLFSHIVLGDDPEVQHGKPDPDIFLACAKRFSPPP 188
Query: 182 --GDCVMVGDTLETDIQGGLNAGLKATVW 208
C++ D ++ L AG++ +
Sbjct: 189 AMEKCLVFEDAP-NGVEAALAAGMQVVMV 216
>2C4N-A nrPDB
Length = 250
Score = 53.3 bits (126), Expect = 9e-08, Method: Composition-based stats.
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 8/116 (6%)
Query: 123 KEVRLLLLTNGDRQTQREKIEAC-ACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQP 181
+ TN R AC A + + + KP+P I N +
Sbjct: 135 ANGARFIATN-PDTHGRGFYPACGALCAGIEKISGRKPFYVGKPSPWIIRAALNKMQAHS 193
Query: 182 GDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPL---KSSPV-PHYMVSSVLEL 233
+ V+VGD L TDI G AGL+ + + +G+ L S P P ++ SV E+
Sbjct: 194 EETVIVGDNLRTDILAGFQAGLETILVL--SGVSSLDDIDSMPFRPSWIYPSVAEI 247
>2X4D-A nrPDB
Length = 271
Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats.
Identities = 48/264 (18%), Positives = 82/264 (31%), Gaps = 36/264 (13%)
Query: 3 LSRVRAVFFDLDNTLIDTAGAS--------------RRGMLEVIKLLQSKYHYKEEAEII 48
L+ VR V D+ L D+ +R L+V + E
Sbjct: 9 LAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESAASRAELVGQ 68
Query: 49 CDKVQVKLSKECFH---PYNTCITDLRTSH----WEEAIQETKGGAA----NRKLAEECY 97
++ +S++ P I R + ++ N + +
Sbjct: 69 LQRLGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAG 128
Query: 98 FLWKSTRLQHM--TLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVV 155
+ + + L E K +L L K T+G ++A A V
Sbjct: 129 ESFSYQNMNNAFQVLMELEKPVLISLGKGRYYAA-TSGLMLDVGPYMKALEYACGIKAEV 187
Query: 156 VGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIV 215
VG KP+P F +GV+ VM+GD + D+ G G++A
Sbjct: 188 VG------KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP 241
Query: 216 PLKSSP--VPHYMVSSVLELPALL 237
+ P V ++ E LL
Sbjct: 242 SDEHHPEVKADGYVDNLAEAVDLL 265
>3QUB-A nrPDB
Length = 243
Score = 52.2 bits (123), Expect = 2e-07, Method: Composition-based stats.
Identities = 33/212 (15%), Positives = 68/212 (32%), Gaps = 29/212 (13%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
+++AV FD+D L ++ YH E + + LS+E + +
Sbjct: 23 KLKAVLFDMDGVLFNS----------------MPYH-SEAWHQVMKTHGLDLSREEAYMH 65
Query: 65 NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL--AEDVKAMLTELR 122
S Q G A ++ E Y + +L +++
Sbjct: 66 ---AGRTGASTINIVFQRELGKEATQEEIESIYHEKSILFNSYPEAERMPGAWELLQKVK 122
Query: 123 KEVRLLLLTNGDRQTQREKIEAC--ACQSYF--DAVVVGGEQREEKPAPSIFYYCCNLLG 178
E ++ G Q +E F + +V + + KP P + G
Sbjct: 123 SEGLTPMVVTGS--GQLSLLERLEHNFPGMFHKELMVTAFDVKYGKPNPEPYLMALKKGG 180
Query: 179 VQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
++ + V++ + ++ G AG+
Sbjct: 181 LKADEAVVIENAP-LGVEAGHKAGIFTIAVNT 211
>1PW5-A nrPDB
Length = 253
Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats.
Identities = 39/228 (17%), Positives = 73/228 (32%), Gaps = 20/228 (8%)
Query: 3 LSRVRAVFFDLDNT--LIDTAGASRRGMLEVIKLLQSKYHY--------KEEAEIICDKV 52
L ++ D+D T L D+ LE +K ++ + ++ +
Sbjct: 2 LDKIELFILDMDGTFYLDDSLLPGSLEFLETLKEKNKRFVFFTNNSSLGAQDYVRKLRNM 61
Query: 53 QVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAE 112
V + + + + G +K+ E + + L
Sbjct: 62 GVDVPDDAVVTSGEITAEHMLKRFGRCRIFLLGTPQLKKVFEAYGHVIDEENPDFVVLGF 121
Query: 113 DVKAMLTELRKEVRLL------LLTNGDRQTQREKIEACACQSYFDAVVVGGEQR----E 162
D L+K LL + T+ D ++ S A+ ++
Sbjct: 122 DKTLTYERLKKACILLRKGKFYIATHPDINCPSKEGPVPDAGSIMAAIEASTGRKPDLIA 181
Query: 163 EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
KP P + GV MVGD L TD++ G NAG+ + + +
Sbjct: 182 GKPNPLVVDVISEKFGVPKERMAMVGDRLYTDVKLGKNAGIVSILVLT 229
>3PDW-A nrPDB
Length = 266
Score = 50.2 bits (118), Expect = 8e-07, Method: Composition-based stats.
Identities = 40/229 (17%), Positives = 66/229 (28%), Gaps = 19/229 (8%)
Query: 1 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHY-------KEEAEIICDKVQ 53
M L + DLD T+ + V L Y + + DK+
Sbjct: 1 MSLKTYKGYLIDLDGTMYNGTEKIEEACEFVRTLKDRGVPYLFVTNNSSRTPKQVADKLV 60
Query: 54 ---VKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL 110
+ ++E + ++A G R+ EE + + +
Sbjct: 61 SFDIPATEEQVFTTSMATAQHIAQQKKDASVYVIGEEGIRQAIEENGLTFGGENADFVVV 120
Query: 111 AEDVKAMLTELR------KEVRLLLLTNGDRQTQREKIEACA---CQSYFDAVVVGGEQR 161
D + + + TNGD E+ S
Sbjct: 121 GIDRSITYEKFAVGCLAIRNGARFISTNGDIAIPTERGLLPGNGSLTSVLTVSTGVQPVF 180
Query: 162 EEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
KP I +LG + +MVGD TDI G+NAG+ +
Sbjct: 181 IGKPESIIMEQAMRVLGTDVSETLMVGDNYATDIMAGINAGMDTLLVHT 229
>3NUQ-A nrPDB
Length = 282
Score = 48.3 bits (113), Expect = 3e-06, Method: Composition-based stats.
Identities = 50/246 (20%), Positives = 89/246 (36%), Gaps = 32/246 (13%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
++ FFD+DN L ++ M + I + +KLS E H N
Sbjct: 57 LKVFFFDIDNCLYKSSTRIHDLMQQSILRFF--------------QTHLKLSPEDAHVLN 102
Query: 66 TCITDLRTSHWEEAIQETKGGAA-NRKLAEECYFLWKSTRLQHMTLAEDVK--AMLTELR 122
S+++E +G ++ A E L + L D+ ML LR
Sbjct: 103 -------NSYYKEYGLAIRGLVMFHKVNALEYNRLVDDSLPLQDILKPDIPLRNMLLRLR 155
Query: 123 KEVR---LLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREE----KPAPSIFYYCCN 175
+ + L L TN + + FD + R + KP F
Sbjct: 156 QSGKIDKLWLFTNAYKNHAIRCLRLLGIADLFDGLTYCDYSRTDTLVCKPHVKAFEKAMK 215
Query: 176 LLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVP-LKSSPVPHYMVSSVLELP 234
G+ + D +I+ G+ G+K + + +N + L +P ++S +LELP
Sbjct: 216 ESGLARYENAYFIDDSGKNIETGIKLGMKTCIHLVENEVNEILGQTPEGAIVISDILELP 275
Query: 235 ALLQSI 240
++ +
Sbjct: 276 HVVSDL 281
>4Y2Y-A nrPDB
Length = 561
Score = 46.8 bits (109), Expect = 9e-06, Method: Composition-based stats.
Identities = 39/243 (16%), Positives = 85/243 (34%), Gaps = 30/243 (12%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+RA FDLD L A G + E + + + + + P
Sbjct: 3 LRAAVFDLDGVLALPAVFGVLG--------------RTEEALALPRGLLNDAFQKGGPEG 48
Query: 66 TCITDLRT----SHW----EEAIQETKGGAANRKLAEEC--YFLWKSTRLQHMTLAEDVK 115
++ S W EE ++ A L + ++ ++
Sbjct: 49 ATTRLMKGEITLSQWIPLMEENCRKCSETA-KVCLPKNFSIKEIFDKAISARKINRPMLQ 107
Query: 116 AMLTELRKEVRLLLLTNG--DRQTQREKIEACACQ--SYFDAVVVGGEQREEKPAPSIFY 171
A L +K +LTN D + +R+ + C+ +FD ++ + KP P I+
Sbjct: 108 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 167
Query: 172 YCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVL 231
+ + L P + V + D + +++ + G+ + + + + ++++
Sbjct: 168 FLLDTLKASPSEVVFLDD-IGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPA 226
Query: 232 ELP 234
LP
Sbjct: 227 PLP 229
>4PNH-A nrPDB
Length = 199
Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats.
Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVP 223
KP P + + P D +VGD+L D+Q G G + + + G L + +P
Sbjct: 119 KPMPGMMKLIAERFEIDPADTPVVGDSLR-DLQAGAALGFRPHLVLTGKGKKTLAAGGLP 177
Query: 224 H 224
Sbjct: 178 E 178
>2B0C-A nrPDB
Length = 206
Score = 44.5 bits (103), Expect = 4e-05, Method: Composition-based stats.
Identities = 42/223 (18%), Positives = 77/223 (34%), Gaps = 38/223 (17%)
Query: 10 FFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCIT 69
FDL N ++D G + ++ + K+ FH
Sbjct: 11 IFDLGNVIVDIDFNRVLGAWSDLT-----------------RIPLASLKKSFHMGEAFHQ 53
Query: 70 DLRTSHWEEAIQETK-GGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV-RL 127
R +EA E A E+ W++ + L +V A++ +LR++ R+
Sbjct: 54 HERGEISDEAFAEALCHEMALPLSYEQFSHGWQAV---FVALRPEVIAIMHKLREQGHRV 110
Query: 128 LLLTNGDRQT----QREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
++L+N +R E E D + + + KP I+ + G P D
Sbjct: 111 VVLSNTNRLHTTFWPEEYPEIRDAA---DHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD 167
Query: 184 CVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYM 226
V D + I+G G+ + + +K +P Y
Sbjct: 168 TVFFDDNADN-IEGANQLGITSILVKDKT--------TIPDYF 201
>1CR6-A nrPDB
Length = 554
Score = 43.3 bits (100), Expect = 9e-05, Method: Composition-based stats.
Identities = 35/234 (14%), Positives = 81/234 (34%), Gaps = 12/234 (5%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+R FDLD L + A E L + + +L K ++
Sbjct: 3 LRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKI-TFS 61
Query: 66 TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
+ + S+ + + N +++ + + L +A + +K
Sbjct: 62 QWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPML----QAAIALKKKGF 117
Query: 126 RLLLLTN-----GDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
++TN GD++ ++ C +FD ++ + KP P I+ + + L +
Sbjct: 118 TTCIVTNNWLDDGDKRDSLAQM-MCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAK 176
Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELP 234
P + V + D ++++ + G+ + N + + L +P
Sbjct: 177 PNEVVFLDD-FGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP 229
>4JB3-A nrPDB
Length = 228
Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats.
Identities = 38/209 (18%), Positives = 67/209 (32%), Gaps = 28/209 (13%)
Query: 4 SRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHP 63
S ++ + FD ++D + L +A+ DK +H
Sbjct: 22 SMIKNIVFDFGGVIVDIDRDKAVQAFIKLGL--------ADADTRLDK---------YHQ 64
Query: 64 YNTCITDLRTSHWEEAIQETKGGAANRKLA-EECYFLWKSTRLQHMTLAEDVKAMLTELR 122
+ ++ G R+L EE W + + +L LR
Sbjct: 65 TGIFQELEEGKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNE--VDLRKLDYIL-GLR 121
Query: 123 KEVRLLLLTNGD------RQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNL 176
K + LL+N + + E Y D + + + KPAP IF +
Sbjct: 122 KSYHVYLLSNTNPFVMSWACSPEFSSEGKPLNDYCDKLYLSYQLGHTKPAPEIFDFMIKD 181
Query: 177 LGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
V P + + V D ++I G G +
Sbjct: 182 SHVIPSETLFVDD-GSSNIHIGKELGFET 209
>3L8F-A nrPDB
Length = 187
Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats.
Identities = 31/162 (19%), Positives = 60/162 (37%), Gaps = 27/162 (16%)
Query: 103 TRLQHMTLAEDVKAMLTELRK-EVRLLLLTNGD-------RQTQREKIEACACQSYFDAV 154
+ + + V + EL+K L+++TN + Q E + S D
Sbjct: 24 HEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRD 83
Query: 155 VVGG--------------EQRE----EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQ 196
V E R+ KP P + + L + MVGD LE D+Q
Sbjct: 84 VDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLE-DMQ 142
Query: 197 GGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
+ A + V + + ++ ++++S+ +LP ++
Sbjct: 143 AAVAANVGTKVLVRTGKPITPEAENAADWVLNSLADLPQAIK 184
>3L1U-A nrPDB
Length = 211
Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats.
Identities = 31/162 (19%), Positives = 60/162 (37%), Gaps = 27/162 (16%)
Query: 103 TRLQHMTLAEDVKAMLTELRK-EVRLLLLTNGD-------RQTQREKIEACACQSYFDAV 154
+ + + V + EL+K L+++TN + Q E + S D
Sbjct: 44 HEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRD 103
Query: 155 VVGG--------------EQRE----EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQ 196
V E R+ KP P + + L + MVGD LE D+Q
Sbjct: 104 VDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLE-DMQ 162
Query: 197 GGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
+ A + V + + ++ ++++S+ +LP ++
Sbjct: 163 AAVAANVGTKVLVRTGKPITPEAENAADWVLNSLADLPQAIK 204
>2O2X-A nrPDB
Length = 218
Score = 40.6 bits (93), Expect = 7e-04, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 150 YFDAVVVGGEQRE---EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKAT 206
Y +A V + KP P + L + ++VGD L D+Q G AGL
Sbjct: 120 YHEAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVGDKL-ADMQAGKRAGLAQG 178
Query: 207 VWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
++ V + P S + +L A ++++
Sbjct: 179 WLVDGEAAVQPGFAIRPLRDSSELGDLLAAIETL 212
>4I9G-A nrPDB
Length = 361
Score = 38.3 bits (87), Expect = 0.003, Method: Composition-based stats.
Identities = 23/101 (22%), Positives = 38/101 (37%), Gaps = 6/101 (5%)
Query: 113 DVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAV---VVGGEQREEKPAPSI 169
D+ +R L + N D E+ S A+ + KPAP++
Sbjct: 141 DLAEAALAIRAGA-LWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPAL 199
Query: 170 FYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
++VGD L+TDI+G AGL + + +
Sbjct: 200 MTEAVAR--GDFRAALVVGDRLDTDIEGANAAGLPSLMVLT 238
>2HO4-A nrPDB
Length = 259
Score = 36.8 bits (83), Expect = 0.010, Method: Composition-based stats.
Identities = 46/253 (18%), Positives = 84/253 (33%), Gaps = 42/253 (16%)
Query: 6 VRAVFFDLDNTL--IDTAGASRRGMLEVIKLLQSKYHY--------KEEAEIICDKVQVK 55
++AV DL+ TL D A + L+ ++ + K++ K++ +
Sbjct: 7 LKAVLVDLNGTLHIEDAAVPGAQEALKRLRATSVMVRFVTNTTKETKKDLLERLKKLEFE 66
Query: 56 LSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVK 115
+S++ T +T R ++ ++ +R L E F T+ + +
Sbjct: 67 ISEDEIF---TSLTAARNLIEQKQVRPML-LLDDRALPE---FTGVQTQDPNAVVIGLAP 119
Query: 116 AML--TELRKEVRLLL---------------LTNGDRQTQREKIEACACQSYFDAVVVGG 158
L + RLLL +G + A + A+VVG
Sbjct: 120 EHFHYQLLNQAFRLLLDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKAMVVG- 178
Query: 159 EQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLK 218
KP + F P + VM+GD D+ G N G+ + +
Sbjct: 179 -----KPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGMLGILVKTGKYKAADE 233
Query: 219 SS--PVPHYMVSS 229
P P+ S
Sbjct: 234 EKINPPPYLTCES 246
>3L8H-A nrPDB
Length = 179
Score = 36.4 bits (82), Expect = 0.011, Method: Composition-based stats.
Identities = 16/61 (26%), Positives = 22/61 (36%), Gaps = 1/61 (1%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVP 223
KP P ++ V VGD+L D+Q AG + NG L +P
Sbjct: 101 KPLPGMYRDIARRYDVDLAGVPAVGDSLR-DLQAAAQAGCAPWLVQTGNGRKTLAQGGLP 159
Query: 224 H 224
Sbjct: 160 E 160
>1U7O-A nrPDB
Length = 164
Score = 36.0 bits (81), Expect = 0.015, Method: Composition-based stats.
Identities = 21/102 (20%), Positives = 33/102 (32%), Gaps = 11/102 (10%)
Query: 101 KSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDR--QTQREKIEACACQSYFDAVVVGG 158
+ R Q++ L +V +L L+ + + Q + +E YF
Sbjct: 38 RDRRGQNIQLYPEVPEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLGKYFI------ 91
Query: 159 EQREEKPAPSI--FYYCCNLLGVQPGDCVMVGDTLETDIQGG 198
QRE P + F + GV V D I G
Sbjct: 92 -QREIYPGSKVTHFERLHHKTGVPFSQMVFFDDENRNIIDVG 132
>3HLT-A nrPDB
Length = 266
Score = 36.0 bits (81), Expect = 0.016, Method: Composition-based stats.
Identities = 15/69 (21%), Positives = 25/69 (36%), Gaps = 2/69 (2%)
Query: 163 EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSS-- 220
KP + F G +P + VM+GD D+ G + G+ + +
Sbjct: 178 GKPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKIN 237
Query: 221 PVPHYMVSS 229
P P+ S
Sbjct: 238 PPPYLTCES 246
>2QLT-A nrPDB
Length = 275
Score = 35.2 bits (79), Expect = 0.030, Method: Composition-based stats.
Identities = 35/194 (18%), Positives = 65/194 (33%), Gaps = 34/194 (17%)
Query: 5 RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
++ A FD+D T+I + A + K K ++ E + + +
Sbjct: 34 KINAALFDVDGTIIISQPAIAAFWRDFGK---DKPYFDAE-----HVIHISHGWRTYDAI 85
Query: 65 NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
D EE + + G K E + + +L + L L KE
Sbjct: 86 AKFAPDFAD---EEYVNK-LEGEIPEKYGEHSIEVPGAVKLCNA---------LNALPKE 132
Query: 125 VRLLLLTNGDRQTQREKIEACACQS--YFDAVVVGGEQREEKPAPSIFYYCCNLLGV--- 179
+ + T+G R ++ + + YF + + ++ KP P + N LG
Sbjct: 133 -KWAVATSGTRDMAKKWFDILKIKRPEYF---ITANDVKQGKPHPEPYLKGRNGLGFPIN 188
Query: 180 --QP--GDCVMVGD 189
P V+ D
Sbjct: 189 EQDPSKSKVVVFED 202
>5YA1-A nrPDB
Length = 540
Score = 32.9 bits (73), Expect = 0.14, Method: Composition-based stats.
Identities = 11/49 (22%), Positives = 20/49 (40%)
Query: 2 GLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICD 50
G +RAV FDL+ I A R + ++ + ++ C+
Sbjct: 30 GTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACE 78
>3IRU-A nrPDB
Length = 277
Score = 32.1 bits (71), Expect = 0.21, Method: Composition-based stats.
Identities = 41/202 (20%), Positives = 67/202 (33%), Gaps = 33/202 (16%)
Query: 71 LRTSHWEEAIQETKGGAANRKLAEECYFLW----KSTRLQHMTLAEDVKAMLTELRKEVR 126
L S A KG A+N + + Y L+ Q L K + +L +
Sbjct: 69 LGNSRIANAWLSIKGQASNEEDIKRLYDLFAPIQTRIVAQRSQLIPGWKEVFDKLIAQGI 128
Query: 127 LLLLTNGDRQTQR-EKIEACACQSYFDA-VVVGGEQREEKPAPSIFYYCCNLLGV-QPGD 183
+ G + A Q Y A V + +P P + L V
Sbjct: 129 KVGGNTGYGPGMMAPALIAAKEQGYTPASTVFATDVVRGRPFPDMALKVALELEVGHVNG 188
Query: 184 CVMVGDTLETDIQGGLNAGLKATVWINKNG-----------IVPLKSSPV---------- 222
C+ V DTL I+ GL AG+ TV ++ +G +
Sbjct: 189 CIKVDDTL-PGIEEGLRAGM-WTVGVSCSGNEVGLDREDWQALSSDEQQSYRQHAEQRLF 246
Query: 223 ---PHYMVSSVLELPALLQSID 241
HY++ SV +L ++ ++
Sbjct: 247 NAGAHYVIDSVADLETVITDVN 268
>6GRI-C nrPDB
Length = 272
Score = 30.2 bits (66), Expect = 0.91, Method: Composition-based stats.
Identities = 16/82 (19%), Positives = 27/82 (32%), Gaps = 7/82 (8%)
Query: 134 DRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD------CVM- 186
E + C QS + ++ G +R KP ++ Y + +M
Sbjct: 154 PLSQALEPVATCNTQSLYRSLSGGDSERLGKPHFALVYCIIFEKALFKYRYRGYRMALME 213
Query: 187 VGDTLETDIQGGLNAGLKATVW 208
G + + GLK VW
Sbjct: 214 TGSMYQNAVLVADQIGLKNRVW 235
>2WM8-A nrPDB
Length = 187
Score = 29.8 bits (65), Expect = 1.2, Method: Composition-based stats.
Identities = 16/97 (16%), Positives = 27/97 (27%), Gaps = 11/97 (11%)
Query: 101 KSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDR--QTQREKIEACACQSYFDAVVVGG 158
+ R Q + L +V +L L+ + + + +E YF
Sbjct: 60 RDRRGQDVRLYPEVPEVLKRLQSLGVPGAAASRTSEIEGANQLLELFDLFRYFV------ 113
Query: 159 EQREEKPAPSI--FYYCCNLLGVQPGDCVMVGDTLET 193
RE P I F G+ + D
Sbjct: 114 -HREIYPGSKITHFERLQQKTGIPFSQMIFFDDERRN 149
>1PZ1-A nrPDB
Length = 333
Score = 29.4 bits (64), Expect = 1.5, Method: Composition-based stats.
Identities = 24/125 (19%), Positives = 46/125 (36%), Gaps = 12/125 (9%)
Query: 3 LSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFH 62
+ +RA D TLIDTA A G E I K + K + I+ K +
Sbjct: 37 IETIRAAL-DQGITLIDTAPAYGFGQSEEIVGKAIKEYMKRDQVILATKTALDWKNNQLF 95
Query: 63 PYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELR 122
R ++ ++E + ++L + L++ + E+ ++ EL
Sbjct: 96 ---------RHANRARIVEEVENSL--KRLQTDYIDLYQVHWPDPLVPIEETAEVMKELY 144
Query: 123 KEVRL 127
++
Sbjct: 145 DAGKI 149
>3WDH-A nrPDB
Length = 710
Score = 27.9 bits (60), Expect = 4.0, Method: Composition-based stats.
Identities = 13/67 (19%), Positives = 23/67 (34%), Gaps = 2/67 (2%)
Query: 54 VKLSKECFH-PYNTCITDLRTSH-WEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA 111
K + ++ P D WEE ++E RK FL +HM
Sbjct: 576 KKGVENSYNSPDEVNQVDWNEKSRWEEDVREIMKLIELRKKHGAFRFLTADQVRRHMKFY 635
Query: 112 EDVKAML 118
+ +++
Sbjct: 636 DTHPSVI 642
>5MSN-A nrPDB
Length = 293
Score = 27.9 bits (60), Expect = 4.1, Method: Composition-based stats.
Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 6/71 (8%)
Query: 61 FHPYNTCITDLRTSHW---EEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAM 117
F P + I LR H+ ++ +Q E L++ LQ ED+K +
Sbjct: 204 FFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFR---LQSQWDLEDIKPL 260
Query: 118 LTELRKEVRLL 128
+ EL +
Sbjct: 261 IEELNSRGMKI 271
>5OKI-C nrPDB
Length = 380
Score = 27.5 bits (59), Expect = 4.9, Method: Composition-based stats.
Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 6/71 (8%)
Query: 61 FHPYNTCITDLRTSHW---EEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAM 117
F P + I LR H+ ++ +Q E L++ LQ ED+K +
Sbjct: 291 FFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFR---LQSQWDLEDIKPL 347
Query: 118 LTELRKEVRLL 128
+ EL +
Sbjct: 348 IEELNSRGMKI 358
>2LEF-A nrPDB
Length = 86
Score = 27.1 bits (58), Expect = 7.7, Method: Composition-based stats.
Identities = 11/37 (29%), Positives = 14/37 (37%), Gaps = 3/37 (8%)
Query: 79 AIQETKGGAANRKLAEE---CYFLWKSTRLQHMTLAE 112
AI + G + EE Y L + R HM L
Sbjct: 32 AINQILGRRWHALSREEQAKYYELARKERQLHMQLYP 68
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.310 0.118 0.280
Lambda K H
0.267 0.0358 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,314,678
Number of Sequences: 36641
Number of extensions: 241281
Number of successful extensions: 867
Number of sequences better than 10.0: 49
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 766
Number of HSP's gapped (non-prelim): 92
length of query: 248
length of database: 10,336,785
effective HSP length: 95
effective length of query: 153
effective length of database: 6,855,890
effective search space: 1048951170
effective search space used: 1048951170
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 57 (26.8 bits)