BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= Q8TBE9
         (248 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

4KNV-A nrPDB                                                          495   e-141
2GFH-A nrPDB                                                          493   e-140
2YY6-A nrPDB                                                           56   1e-08
5OLW-A nrPDB                                                           46   2e-05
2HSZ-A nrPDB                                                           43   1e-04
4BX2-A nrPDB                                                           43   1e-04
2P27-A nrPDB                                                           42   3e-04
3KBB-A nrPDB                                                           41   4e-04
4BKM-A nrPDB                                                           41   6e-04
2HI0-A nrPDB                                                           38   0.003
3NAS-A nrPDB                                                           37   0.005
2C4N-A nrPDB                                                           35   0.023
3PDW-A nrPDB                                                           35   0.033
2X4D-A nrPDB                                                           35   0.038
1TE2-A nrPDB                                                           34   0.045
4RN3-A nrPDB                                                           34   0.072
3L5K-A nrPDB                                                           33   0.11 
4G9B-A nrPDB                                                           33   0.13 
4GIB-A nrPDB                                                           32   0.20 
5BPD-A nrPDB                                                           31   0.43 
1PW5-A nrPDB                                                           31   0.55 
2B7N-A nrPDB                                                           30   0.78 
1RQL-A nrPDB                                                           30   0.78 
4PNH-A nrPDB                                                           30   0.80 
3HLT-A nrPDB                                                           30   1.3  
4I9G-A nrPDB                                                           29   1.5  
1CR6-A nrPDB                                                           28   2.9  
2HO4-A nrPDB                                                           28   3.0  
4Y2Y-A nrPDB                                                           28   3.0  

>4KNV-A nrPDB
          Length = 241

 Score =  495 bits (1275), Expect = e-141,   Method: Compositional matrix adjust.
 Identities = 237/239 (99%), Positives = 238/239 (99%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           +RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN
Sbjct: 1   MRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 60

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
           TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV
Sbjct: 61  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 120

Query: 126 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 185
           RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV
Sbjct: 121 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 180

Query: 186 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKV 244
           MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDC V
Sbjct: 181 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCLV 239


>2GFH-A nrPDB
          Length = 260

 Score =  493 bits (1268), Expect = e-140,   Method: Compositional matrix adjust.
 Identities = 233/247 (94%), Positives = 243/247 (98%)

Query: 1   MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
           MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC
Sbjct: 13  MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 72

Query: 61  FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE 120
           FHPY+TCITD+RTSHWEEAIQETKGGA NRKLAEECYFLWKSTRLQHM LA+DVKAMLTE
Sbjct: 73  FHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMILADDVKAMLTE 132

Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
           LRKEVRLLLLTNGDRQTQREKIEACACQSYFDA+V+GGEQ+EEKPAPSIFY+CC+LLGVQ
Sbjct: 133 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVIGGEQKEEKPAPSIFYHCCDLLGVQ 192

Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
           PGDCVMVGDTLETDIQGGLNAGLKATVWINK+G VPL SSP+PHYMVSSVLELPALLQSI
Sbjct: 193 PGDCVMVGDTLETDIQGGLNAGLKATVWINKSGRVPLTSSPMPHYMVSSVLELPALLQSI 252

Query: 241 DCKVSMS 247
           DCKVSMS
Sbjct: 253 DCKVSMS 259


>2YY6-A nrPDB
          Length = 213

 Score = 56.2 bits (134), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 56/241 (23%), Positives = 104/241 (43%), Gaps = 40/241 (16%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           +R + FDLD TLID+A                     ++  +  +K   +L  E ++P N
Sbjct: 1   MRVILFDLDGTLIDSA---------------------KDIALALEKTLKELGLEEYYPDN 39

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL----AEDVKAMLTEL 121
                  T +    ++         K  EE   +++   L++  +      ++   L  L
Sbjct: 40  V------TKYIGGGVRALLEKVLKDKFREEYVEVFRKHYLENPVVYTKPYPEIPYTLEAL 93

Query: 122 R-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
           + K  +L +++N   +  ++ ++      YFD +V G    E+KP+P+       +LG +
Sbjct: 94  KSKGFKLAVVSNKLEELSKKILDILNLSGYFDLIVGGDTFGEKKPSPTPVLKTLEILGEE 153

Query: 181 PGDCVMVGDTLETDIQGGLNAGLKA--TVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
           P   ++VGDT + DI+ G  AG K    +W    G V L S  +P + +S   +L  L+ 
Sbjct: 154 PEKALIVGDT-DADIEAGKRAGTKTALALW----GYVKLNSQ-IPDFTLSRPSDLVKLMD 207

Query: 239 S 239
           +
Sbjct: 208 N 208


>5OLW-A nrPDB
          Length = 227

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 45/220 (20%)

Query: 7   RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNT 66
           +AV FDLD  + DTA                +YH++   + + +++ +      F+    
Sbjct: 3   KAVLFDLDGVITDTA----------------EYHFRA-WKALAEEIGINGVDRQFN---- 41

Query: 67  CITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKA---------M 117
               L+    E+++Q+    A  +  AEE   L K     ++ + +DV           +
Sbjct: 42  --EQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQL 99

Query: 118 LTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
           L +LR     + L +  +      +E      YFDA+    E    KPAP IF    + +
Sbjct: 100 LKDLRSNKIKIALASASKNGPF-LLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAV 158

Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPL 217
           GV P + + + D+     Q G+ A       I  +G +P+
Sbjct: 159 GVAPSESIGLEDS-----QAGIQA-------IKDSGALPI 186


>2HSZ-A nrPDB
          Length = 243

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 110 LAEDVKAMLTELRKEVRLL-LLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPS 168
           L  +VK  L  L+ +  +L ++TN   +  +  + A      F  ++ G    E KP P+
Sbjct: 115 LYPNVKETLEALKAQGYILAVVTNKPTKHVQPILTAFGIDHLFSEMLGGQSLPEIKPHPA 174

Query: 169 IFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAG 202
            FYY C   G+ P   + VGD+ + DI    +AG
Sbjct: 175 PFYYLCGKFGLYPKQILFVGDS-QNDIFAAHSAG 207


>4BX2-A nrPDB
          Length = 293

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 19/115 (16%)

Query: 130 LTNGDRQTQREKIEACA-CQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVG 188
           L++G R      + A     S   A+VVG      KP+P +F        V P   +MVG
Sbjct: 181 LSDGSRTPGTGSLAAAVETASGRQALVVG------KPSPYMFQCITEDFSVDPARTLMVG 234

Query: 189 DTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYMVSSVLEL 233
           D LETDI  G   G+  T  +   G+  L+ +           VPHY V S+ +L
Sbjct: 235 DRLETDILFGHRCGM--TTVLTLTGVSSLEEAQAYLTAGQRDLVPHYYVESIADL 287


>2P27-A nrPDB
          Length = 306

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 19/115 (16%)

Query: 130 LTNGDRQTQREKIEACA-CQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVG 188
           L++G R      + A     S   A+VVG      KP+P +F        + P   +MVG
Sbjct: 186 LSDGSRTPGTGSLAAAVETASGRQALVVG------KPSPYMFECITENFSIDPARTLMVG 239

Query: 189 DTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYMVSSVLEL 233
           D LETDI  G   G+  T  +   G+  L+ +           VPHY V S+ +L
Sbjct: 240 DRLETDILFGHRCGM--TTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADL 292


>3KBB-A nrPDB
          Length = 216

 Score = 41.2 bits (95), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 123 KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPG 182
           K ++L L T+  ++   E++     + YFD +V G + +  KP P I+      L V P 
Sbjct: 99  KRIKLALATSTPQREALERLRRLDLEKYFDVMVFGDQVKNGKPDPEIYLLVLERLNVVPE 158

Query: 183 DCVMVGDTLETDIQGGLNAGLK 204
             V+  D+ ++ ++   +AG++
Sbjct: 159 KVVVFEDS-KSGVEAAKSAGIE 179


>4BKM-A nrPDB
          Length = 309

 Score = 40.8 bits (94), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 16/121 (13%)

Query: 127 LLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREE----KPAPSIFYYCCNLLGVQPG 182
           LL+ TN D +   E     A        V    QR+     KP+P +F        V P 
Sbjct: 185 LLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSPYMFQCITEDFSVDPA 244

Query: 183 DCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYMVSSVLE 232
             +MVGD LETDI  G   G+  T  +   G+  L+ +           VPHY V S+ +
Sbjct: 245 RTLMVGDRLETDILFGHRCGM--TTVLTLTGVSSLEEAQAYLTAGQRDLVPHYYVESIAD 302

Query: 233 L 233
           L
Sbjct: 303 L 303


>2HI0-A nrPDB
          Length = 240

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 50/227 (22%), Positives = 94/227 (41%), Gaps = 25/227 (11%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEE--AEIICDKVQVKLSKECFH 62
           + +A  FD+D T++DT+      +    +    ++ +  E         V V +++   +
Sbjct: 3   KYKAAIFDMDGTILDTSADLTSALNYAFEQTGHRHDFTVEDIKNFFGSGVVVAVTRALAY 62

Query: 63  PYNTCITDL-----RTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA-EDVKA 116
              +    L     +     EA+ +T+    NR L  E +  + +   Q  T     +  
Sbjct: 63  EAGSSRESLVAFGTKDEQIPEAVTQTE---VNRVL--EVFKPYYADHCQIKTGPFPGILD 117

Query: 117 MLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCN 175
           ++  LR K V+L +++N   +  +  +E     S FD  +        KPAP +   C  
Sbjct: 118 LMKNLRQKGVKLAVVSNKPNEAVQVLVEELFPGS-FDFALGEKSGIRRKPAPDMTSECVK 176

Query: 176 LLGVQPGDCVMVGDTLETDIQGGLNA---------GLKATVWINKNG 213
           +LGV    CV +GD+ E DIQ   N+         G ++  ++ K+G
Sbjct: 177 VLGVPRDKCVYIGDS-EIDIQTARNSEMDEIAVNWGFRSVPFLQKHG 222


>3NAS-A nrPDB
          Length = 233

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 31/208 (14%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           ++AV FDLD  + DTA                +YH+     I  +++ +   ++     N
Sbjct: 2   LKAVIFDLDGVITDTA----------------EYHFLAWKHI-AEQIDIPFDRDM----N 40

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA----ED----VKAM 117
             +  +      E+I    G       AE+   + +  R   M ++    ED    +  +
Sbjct: 41  ERLKGISREESLESILIFGGAETKYTNAEKQELMHRKNRDYQMLISKLTPEDLLPGIGRL 100

Query: 118 LTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
           L +L+ E   + L +  R   +  +   A    F A+V      + KP P IF     +L
Sbjct: 101 LCQLKNENIKIGLASSSRNAPK-ILRRLAIIDDFHAIVDPTTLAKGKPDPDIFLTAAAML 159

Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKA 205
            V P DC  + D  E  I    +AG+ A
Sbjct: 160 DVSPADCAAIEDA-EAGISAIKSAGMFA 186


>2C4N-A nrPDB
          Length = 250

 Score = 35.4 bits (80), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 2/72 (2%)

Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINK-NGIVPLKSSPV 222
           KP+P I     N +     + V+VGD L TDI  G  AGL+  + ++  + +  + S P 
Sbjct: 176 KPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSSLDDIDSMPF 235

Query: 223 -PHYMVSSVLEL 233
            P ++  SV E+
Sbjct: 236 RPSWIYPSVAEI 247


>3PDW-A nrPDB
          Length = 266

 Score = 35.0 bits (79), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 21/40 (52%)

Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
           KP   I      +LG    + +MVGD   TDI  G+NAG+
Sbjct: 183 KPESIIMEQAMRVLGTDVSETLMVGDNYATDIMAGINAGM 222


>2X4D-A nrPDB
          Length = 271

 Score = 34.7 bits (78), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 22/42 (52%)

Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
           KP+P  F      +GV+    VM+GD +  D+ G    G++A
Sbjct: 190 KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRA 231


>1TE2-A nrPDB
          Length = 226

 Score = 34.3 bits (77), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 33/195 (16%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
           ++ A  FD+D  LID+     R  L+V+  L      + E   + D + +++        
Sbjct: 8   QILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNE---LPDTLGLRI-------- 56

Query: 65  NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
                D+    W    ++   G + +++ E           + ++L E+ + +L  +R+ 
Sbjct: 57  -----DMVVDLWYA--RQPWNGPSRQEVVERVIA-------RAISLVEETRPLLPGVREA 102

Query: 125 VRL-----LL--LTNGDRQTQREKI-EACACQSYFDAVVVGGEQREEKPAPSIFYYCCNL 176
           V L     LL  L +       EK+      +  FDA+    +    KP P ++  C   
Sbjct: 103 VALCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK 162

Query: 177 LGVQPGDCVMVGDTL 191
           LGV P  CV + D++
Sbjct: 163 LGVDPLTCVALEDSV 177


>4RN3-A nrPDB
          Length = 213

 Score = 33.9 bits (76), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 42/204 (20%), Positives = 78/204 (38%), Gaps = 23/204 (11%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           ++AV +D D  + D+  A+      +++++      ++  E +   +    ++E    + 
Sbjct: 11  IKAVIYDCDGVMFDSFEANLAFYQRIMEMMGRPRLSRDNEEQM-RILHTYANREVLAHFF 69

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
               D     WEEA++   G    R+L            +  M + E  +  L  L+  V
Sbjct: 70  PSPGD-----WEEAVR-CAGAIDYREL------------VPLMIMEEGFREALDTLKGRV 111

Query: 126 RLLLLTNGDRQTQREKI-EACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDC 184
            L + TN  R T  + +    +  SYF  V+        KP P          G+ P + 
Sbjct: 112 GLGVCTN--RSTSMDMVLRLFSLDSYFSIVMTASRVTNPKPHPEPLLKVLEHFGIGPREA 169

Query: 185 VMVGDTLETDIQGGLNAGLKATVW 208
           + VGD+ E D      AG+    +
Sbjct: 170 LFVGDS-EVDRLSAEAAGVPFVAY 192


>3L5K-A nrPDB
          Length = 250

 Score = 33.1 bits (74), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 55/228 (24%), Positives = 87/228 (38%), Gaps = 58/228 (25%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK-----------EEAEIICDKVQV 54
           V  + FD+D  L+DT         E+      KY +            E A+II D +Q+
Sbjct: 30  VTHLIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKALEAAQIIIDVLQL 89

Query: 55  KLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDV 114
            +SK                  EE ++E++      KL E    ++ +  L  M  AE  
Sbjct: 90  PMSK------------------EELVEESQ-----TKLKE----VFPTAAL--MPGAE-- 118

Query: 115 KAMLTELRKE-VRLLLLTNG-----DRQTQREKIEACACQSYFDAVVVGG--EQREEKPA 166
             ++  LRK  +   L T+      D +T R K       S F  +V+G   E +  KP 
Sbjct: 119 -KLIIHLRKHGIPFALATSSRSASFDMKTSRHK----EFFSLFSHIVLGDDPEVQHGKPD 173

Query: 167 PSIFYYCCNLLGVQPG--DCVMVGDTLETDIQGGLNAGLKATVWINKN 212
           P IF  C       P    C++  D     ++  L AG++  +  + N
Sbjct: 174 PDIFLACAKRFSPPPAMEKCLVFEDA-PNGVEAALAAGMQVVMVPDGN 220


>4G9B-A nrPDB
          Length = 243

 Score = 32.7 bits (73), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 47/238 (19%), Positives = 89/238 (37%), Gaps = 43/238 (18%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
           +++ V FDLD  + DTA                  H++   +I  + + + +  +    +
Sbjct: 4   KLQGVIFDLDGVITDTA----------------HLHFQAWQQIAAE-IGISIDAQ----F 42

Query: 65  NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAE-DVKAMLTELRK 123
           N  +  +        I +  G   +    E     ++   L   +L E  V A+L  +R 
Sbjct: 43  NESLKGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPGIRS 102

Query: 124 ---EVRLLLLTNGDRQTQREK---IEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
              ++R   ++ G           + A   + +F       + +  KP P IF   C  L
Sbjct: 103 LLADLRAQQISVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL 162

Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPA 235
           GV P  C+ +      D Q G++A       IN +G   ++S  +   +  + L LP+
Sbjct: 163 GVPPQACIGI-----EDAQAGIDA-------INASG---MRSVGIGAGLTGAQLLLPS 205


>4GIB-A nrPDB
          Length = 250

 Score = 32.3 bits (72), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 19/40 (47%)

Query: 151 FDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDT 190
           FD +   G+ +  KP P IF      L V P +C+ + D 
Sbjct: 157 FDFIADAGKCKNNKPHPEIFLMSAKGLNVNPQNCIGIEDA 196


>5BPD-A nrPDB
          Length = 264

 Score = 31.2 bits (69), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 182 GDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPAL 236
            D   +   LE DI   ++ G+K  + + KN +  LK+S +  Y     LEL AL
Sbjct: 153 ADDGFIAVNLEDDIIKAVDRGVKTKILLTKNLLPRLKASKIIDYAKEGKLELRAL 207


>1PW5-A nrPDB
          Length = 253

 Score = 30.8 bits (68), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 20/40 (50%)

Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
           KP P +        GV      MVGD L TD++ G NAG+
Sbjct: 183 KPNPLVVDVISEKFGVPKERMAMVGDRLYTDVKLGKNAGI 222


>2B7N-A nrPDB
          Length = 273

 Score = 30.4 bits (67), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 3/41 (7%)

Query: 85  GGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
           GGA+N +L  +   + K T L+H+   +D+K+ LT  RK +
Sbjct: 142 GGASNHRLGLDDALMLKDTHLRHV---KDLKSFLTHARKNL 179


>1RQL-A nrPDB
          Length = 267

 Score = 30.4 bits (67), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 4/133 (3%)

Query: 74  SHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE-VRLLLLTN 132
           S W    ++    A  +++ EE   +  +   ++ +    VK ++  LR+  +++   T 
Sbjct: 68  SEWNRVFRQLPTEADIQEMYEEFEEILFAILPRYASPINAVKEVIASLRERGIKIGSTTG 127

Query: 133 GDRQTQREKIEACACQSYF-DAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD-CVMVGDT 190
             R+      +  A Q Y  D +V   +    +P P + Y     LGV P +  + VGDT
Sbjct: 128 YTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELGVYPMNHMIKVGDT 187

Query: 191 LETDIQGGLNAGL 203
           + +D++ G NAG+
Sbjct: 188 V-SDMKEGRNAGM 199


>4PNH-A nrPDB
          Length = 199

 Score = 30.4 bits (67), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 1/61 (1%)

Query: 163 EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPV 222
            KP P +         + P D  +VGD+L  D+Q G   G +  + +   G   L +  +
Sbjct: 118 RKPMPGMMKLIAERFEIDPADTPVVGDSLR-DLQAGAALGFRPHLVLTGKGKKTLAAGGL 176

Query: 223 P 223
           P
Sbjct: 177 P 177


>3HLT-A nrPDB
          Length = 266

 Score = 29.6 bits (65), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 6/51 (11%)

Query: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
           A VVG      KP  + F       G +P + VM+GD    D+ G  + G+
Sbjct: 174 ATVVG------KPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGM 218


>4I9G-A nrPDB
          Length = 361

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 8/45 (17%)

Query: 164 KPAPSIFYYCCNLLGVQPGD---CVMVGDTLETDIQGGLNAGLKA 205
           KPAP++         V  GD    ++VGD L+TDI+G   AGL +
Sbjct: 194 KPAPALMTEA-----VARGDFRAALVVGDRLDTDIEGANAAGLPS 233


>1CR6-A nrPDB
          Length = 554

 Score = 28.5 bits (62), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 130 LTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGD 189
           L +GD++    ++  C    +FD ++   +    KP P I+ +  + L  +P + V + D
Sbjct: 127 LDDGDKRDSLAQM-MCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDD 185


>2HO4-A nrPDB
          Length = 259

 Score = 28.5 bits (62), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 6/51 (11%)

Query: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
           A+VVG      KP  + F          P + VM+GD    D+ G  N G+
Sbjct: 174 AMVVG------KPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGM 218


>4Y2Y-A nrPDB
          Length = 561

 Score = 28.5 bits (62), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 114 VKAMLTELRKEVRLLLLTNG--DRQTQREKIEACACQ--SYFDAVVVGGEQREEKPAPSI 169
           ++A L   +K     +LTN   D + +R+ +    C+   +FD ++   +    KP P I
Sbjct: 106 LQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQI 165

Query: 170 FYYCCNLLGVQPGDCVMVGD 189
           + +  + L   P + V + D
Sbjct: 166 YKFLLDTLKASPSEVVFLDD 185


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

2GFH-A nrPDB                                                          381   e-106
4KNV-A nrPDB                                                          372   e-104
2YY6-A nrPDB                                                          204   2e-53
5OLW-A nrPDB                                                          168   2e-42
4BKM-A nrPDB                                                          127   6e-30
2HSZ-A nrPDB                                                          124   5e-29
4BX2-A nrPDB                                                          110   6e-25
2P27-A nrPDB                                                          107   4e-24
3KBB-A nrPDB                                                          101   4e-22

Sequences not found previously or not previously below threshold:

3NAS-A nrPDB                                                           93   2e-19
4G9B-A nrPDB                                                           88   2e-18
4GIB-A nrPDB                                                           82   2e-16
1RQL-A nrPDB                                                           73   1e-13
4RN3-A nrPDB                                                           69   2e-12
2HDO-A nrPDB                                                           65   2e-11
2HI0-A nrPDB                                                           63   9e-11
1TE2-A nrPDB                                                           62   3e-10
3L5K-A nrPDB                                                           58   5e-09
2C4N-A nrPDB                                                           53   9e-08
2X4D-A nrPDB                                                           53   1e-07
3QUB-A nrPDB                                                           52   2e-07
1PW5-A nrPDB                                                           51   4e-07
3PDW-A nrPDB                                                           50   8e-07
3NUQ-A nrPDB                                                           48   3e-06
4Y2Y-A nrPDB                                                           47   9e-06
4PNH-A nrPDB                                                           45   3e-05
2B0C-A nrPDB                                                           44   4e-05
1CR6-A nrPDB                                                           43   9e-05
4JB3-A nrPDB                                                           43   2e-04
3L8F-A nrPDB                                                           43   2e-04
3L1U-A nrPDB                                                           43   2e-04
2O2X-A nrPDB                                                           41   7e-04
4I9G-A nrPDB                                                           38   0.003
2HO4-A nrPDB                                                           37   0.010
3L8H-A nrPDB                                                           36   0.011
1U7O-A nrPDB                                                           36   0.015
3HLT-A nrPDB                                                           36   0.016
2QLT-A nrPDB                                                           35   0.030
5YA1-A nrPDB                                                           33   0.14 
3IRU-A nrPDB                                                           32   0.21 
6GRI-C nrPDB                                                           30   0.91 
2WM8-A nrPDB                                                           30   1.2  
1PZ1-A nrPDB                                                           29   1.5  
3WDH-A nrPDB                                                           28   4.0  
5MSN-A nrPDB                                                           28   4.1  
5OKI-C nrPDB                                                           28   4.9  
2LEF-A nrPDB                                                           27   7.7  

>2GFH-A nrPDB
          Length = 260

 Score =  381 bits (979), Expect = e-106,   Method: Composition-based stats.
 Identities = 233/247 (94%), Positives = 243/247 (98%)

Query: 1   MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
           MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC
Sbjct: 13  MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 72

Query: 61  FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE 120
           FHPY+TCITD+RTSHWEEAIQETKGGA NRKLAEECYFLWKSTRLQHM LA+DVKAMLTE
Sbjct: 73  FHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMILADDVKAMLTE 132

Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
           LRKEVRLLLLTNGDRQTQREKIEACACQSYFDA+V+GGEQ+EEKPAPSIFY+CC+LLGVQ
Sbjct: 133 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVIGGEQKEEKPAPSIFYHCCDLLGVQ 192

Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
           PGDCVMVGDTLETDIQGGLNAGLKATVWINK+G VPL SSP+PHYMVSSVLELPALLQSI
Sbjct: 193 PGDCVMVGDTLETDIQGGLNAGLKATVWINKSGRVPLTSSPMPHYMVSSVLELPALLQSI 252

Query: 241 DCKVSMS 247
           DCKVSMS
Sbjct: 253 DCKVSMS 259


>4KNV-A nrPDB
          Length = 241

 Score =  372 bits (954), Expect = e-104,   Method: Composition-based stats.
 Identities = 237/239 (99%), Positives = 238/239 (99%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           +RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN
Sbjct: 1   MRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 60

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
           TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV
Sbjct: 61  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 120

Query: 126 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 185
           RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV
Sbjct: 121 RLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCV 180

Query: 186 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKV 244
           MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDC V
Sbjct: 181 MVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCLV 239


>2YY6-A nrPDB
          Length = 213

 Score =  204 bits (519), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 55/239 (23%), Positives = 103/239 (43%), Gaps = 36/239 (15%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           +R + FDLD TLID+A                     ++  +  +K   +L  E ++P N
Sbjct: 1   MRVILFDLDGTLIDSA---------------------KDIALALEKTLKELGLEEYYPDN 39

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA----EDVKAMLTEL 121
                  T +    ++         K  EE   +++   L++  +      ++   L  L
Sbjct: 40  V------TKYIGGGVRALLEKVLKDKFREEYVEVFRKHYLENPVVYTKPYPEIPYTLEAL 93

Query: 122 R-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
           + K  +L +++N   +  ++ ++      YFD +V G    E+KP+P+       +LG +
Sbjct: 94  KSKGFKLAVVSNKLEELSKKILDILNLSGYFDLIVGGDTFGEKKPSPTPVLKTLEILGEE 153

Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQS 239
           P   ++VGDT + DI+ G  AG K    +   G V L S  +P + +S   +L  L+ +
Sbjct: 154 PEKALIVGDT-DADIEAGKRAGTKTA--LALWGYVKLNS-QIPDFTLSRPSDLVKLMDN 208


>5OLW-A nrPDB
          Length = 227

 Score =  168 bits (425), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 45/220 (20%)

Query: 7   RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNT 66
           +AV FDLD  + DTA                +YH++   + + +++ +      F+    
Sbjct: 3   KAVLFDLDGVITDTA----------------EYHFRA-WKALAEEIGINGVDRQFN---- 41

Query: 67  CITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKA---------M 117
               L+    E+++Q+    A  +  AEE   L K     ++ + +DV           +
Sbjct: 42  --EQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQL 99

Query: 118 LTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLL 177
           L +LR     + L +  +      +E      YFDA+    E    KPAP IF    + +
Sbjct: 100 LKDLRSNKIKIALASASKNGPF-LLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAV 158

Query: 178 GVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPL 217
           GV P + + + D+     Q G+ A       I  +G +P+
Sbjct: 159 GVAPSESIGLEDS-----QAGIQA-------IKDSGALPI 186


>4BKM-A nrPDB
          Length = 309

 Score =  127 bits (318), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 42/150 (28%), Positives = 61/150 (40%), Gaps = 20/150 (13%)

Query: 104 RLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQRE- 162
              +M L + V+     L++   LL+ TN D +   E     A        V    QR+ 
Sbjct: 166 HFSYMKLTKAVRY----LQQPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQA 221

Query: 163 ---EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKS 219
               KP+P +F        V P   +MVGD LETDI  G   G+  T  +   G+  L+ 
Sbjct: 222 DIIGKPSPYMFQCITEDFSVDPARTLMVGDRLETDILFGHRCGM--TTVLTLTGVSSLEE 279

Query: 220 SP----------VPHYMVSSVLELPALLQS 239
           +           VPHY V S+ +L   L+ 
Sbjct: 280 AQAYLTAGQRDLVPHYYVESIADLMEGLED 309


>2HSZ-A nrPDB
          Length = 243

 Score =  124 bits (310), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 45/254 (17%), Positives = 89/254 (35%), Gaps = 46/254 (18%)

Query: 2   GLSRVRAVFFDLDNTLIDT---AGASRRGMLEVIKLLQSKYHYKEEA------------- 45
           G+++ + + FDLD TL+++      S    L+ + L Q+  +                  
Sbjct: 19  GMTQFKLIGFDLDGTLVNSLPDLALSINSALKDVNLPQASENLVMTWIGNGADVLSQRAV 78

Query: 46  EIICDKVQVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRL 105
           +  C + + +L+++ F                            +    +  F +     
Sbjct: 79  DWACKQAEKELTEDEF----------------------------KYFKRQFGFYYGENLC 110

Query: 106 QHMTLAEDVKAMLTELRKEVR-LLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEK 164
               L  +VK  L  L+ +   L ++TN   +  +  + A      F  ++ G    E K
Sbjct: 111 NISRLYPNVKETLEALKAQGYILAVVTNKPTKHVQPILTAFGIDHLFSEMLGGQSLPEIK 170

Query: 165 PAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPH 224
           P P+ FYY C   G+ P   + VGD+ + DI    +AG                +   P 
Sbjct: 171 PHPAPFYYLCGKFGLYPKQILFVGDS-QNDIFAAHSAGCAVVGLTYGYNYNIPIAQSKPD 229

Query: 225 YMVSSVLELPALLQ 238
           ++     ++  + Q
Sbjct: 230 WIFDDFADILKITQ 243


>4BX2-A nrPDB
          Length = 293

 Score =  110 bits (274), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 16/133 (12%)

Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQRE----EKPAPSIFYYCCNL 176
           LR    LL+ T+ D                  A V     R+     KP+P +F      
Sbjct: 163 LRDPDCLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFQCITED 222

Query: 177 LGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSP----------VPHYM 226
             V P   +MVGD LETDI  G   G+  T  +   G+  L+ +           VPHY 
Sbjct: 223 FSVDPARTLMVGDRLETDILFGHRCGM--TTVLTLTGVSSLEEAQAYLTAGQRDLVPHYY 280

Query: 227 VSSVLELPALLQS 239
           V S+ +L   L+ 
Sbjct: 281 VESIADLMEGLED 293


>2P27-A nrPDB
          Length = 306

 Score =  107 bits (267), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 38/150 (25%), Positives = 58/150 (38%), Gaps = 17/150 (11%)

Query: 104 RLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQRE- 162
             +H + A+ ++     LR    LL+ T+ D                  A V     R+ 
Sbjct: 152 YDEHFSFAK-LREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQA 210

Query: 163 ---EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKS 219
               KP+P +F        + P   +MVGD LETDI  G   G+  T  +   G+  L+ 
Sbjct: 211 LVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGM--TTVLTLTGVSRLEE 268

Query: 220 SP----------VPHYMVSSVLELPALLQS 239
           +           VPHY V S+ +L   L+ 
Sbjct: 269 AQAYLAAGQHDLVPHYYVESIADLTEGLED 298


>3KBB-A nrPDB
          Length = 216

 Score =  101 bits (250), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 44/211 (20%), Positives = 84/211 (39%), Gaps = 44/211 (20%)

Query: 6   VRAVFFDLDNTLIDTAG----ASRRGMLEVIKLLQSKYHYK-------EEAEIICDKVQV 54
           + AV FD+D  L+DT      A RR      K      H +       E   I+ + +++
Sbjct: 1   MEAVIFDMDGVLMDTEPLYFEAYRRVAESYGKPYTEDLHRRIMGVPEREGLPILMEALEI 60

Query: 55  KLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDV 114
           K S E F                            +++ EE   ++     ++      V
Sbjct: 61  KDSLENF---------------------------KKRVHEEKKRVFSELLKEN----PGV 89

Query: 115 KAMLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYC 173
           +  L  ++ K ++L L T+  ++   E++     + YFD +V G + +  KP P I+   
Sbjct: 90  REALEFVKSKRIKLALATSTPQREALERLRRLDLEKYFDVMVFGDQVKNGKPDPEIYLLV 149

Query: 174 CNLLGVQPGDCVMVGDTLETDIQGGLNAGLK 204
              L V P   V+  D+ ++ ++   +AG++
Sbjct: 150 LERLNVVPEKVVVFEDS-KSGVEAAKSAGIE 179


>3NAS-A nrPDB
          Length = 233

 Score = 92.6 bits (228), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 46/211 (21%), Positives = 76/211 (36%), Gaps = 37/211 (17%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           ++AV FDLD  + DTA                +YH+    + I +++ +           
Sbjct: 2   LKAVIFDLDGVITDTA----------------EYHFLA-WKHIAEQIDIPF-------DR 37

Query: 66  TCITDLRTSHWEEAIQETK--GGAANRKLAEECYFLWKSTRLQHMTLA---------EDV 114
                L+    EE+++     GGA  +    E   L       +  L            +
Sbjct: 38  DMNERLKGISREESLESILIFGGAETKYTNAEKQELMHRKNRDYQMLISKLTPEDLLPGI 97

Query: 115 KAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCC 174
             +L +L+ E   + L +  R    + +   A    F A+V      + KP P IF    
Sbjct: 98  GRLLCQLKNENIKIGLASSSRNAP-KILRRLAIIDDFHAIVDPTTLAKGKPDPDIFLTAA 156

Query: 175 NLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
            +L V P DC  + D  E  I    +AG+ A
Sbjct: 157 AMLDVSPADCAAIEDA-EAGISAIKSAGMFA 186


>4G9B-A nrPDB
          Length = 243

 Score = 88.4 bits (217), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 38/212 (17%), Positives = 80/212 (37%), Gaps = 37/212 (17%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
           +++ V FDLD  + DTA                  H++   + I  ++ + +    F+  
Sbjct: 4   KLQGVIFDLDGVITDTA----------------HLHFQA-WQQIAAEIGISI-DAQFN-- 43

Query: 65  NTCITDLRTSHWEEAIQETK--GGAANRKLAEECYFLWKSTRLQHM---------TLAED 113
                 L+    +E+++     GG      ++E   L     L ++          +   
Sbjct: 44  ----ESLKGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPG 99

Query: 114 VKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYC 173
           ++++L +LR +   + L +         + A   + +F       + +  KP P IF   
Sbjct: 100 IRSLLADLRAQQISVGLASVSLNAPT-ILAALELREFFTFCADASQLKNSKPDPEIFLAA 158

Query: 174 CNLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
           C  LGV P  C+ + D  +  I     +G+++
Sbjct: 159 CAGLGVPPQACIGIEDA-QAGIDAINASGMRS 189


>4GIB-A nrPDB
          Length = 250

 Score = 82.2 bits (201), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 35/209 (16%), Positives = 71/209 (33%), Gaps = 37/209 (17%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           + A  FDLD  + DTA                 YHY      +  KV + +         
Sbjct: 26  IEAFIFDLDGVITDTAY----------------YHYMA-WRKLAHKVGIDI-------DT 61

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKL--AEECYFLWKSTRLQHMTLAEDV--------- 114
                L+     E++         +     EE   + +     +++L +++         
Sbjct: 62  KFNESLKGISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGI 121

Query: 115 KAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCC 174
           +++L +++     + L++  +      +        FD +   G+ +  KP P IF    
Sbjct: 122 ESLLIDVKSNNIKIGLSSASKN-AINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSA 180

Query: 175 NLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
             L V P +C+ + D     I    +A +
Sbjct: 181 KGLNVNPQNCIGIEDA-SAGIDAINSANM 208


>1RQL-A nrPDB
          Length = 267

 Score = 73.0 bits (177), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 51/268 (19%), Positives = 100/268 (37%), Gaps = 35/268 (13%)

Query: 1   MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
           M   ++ AV FD   T +D       G    +++    +H K    I  ++ +  +    
Sbjct: 1   MDRMKIEAVIFDWAGTTVD------YGCFAPLEVFMEIFH-KRGVAITAEEARKPMGLLK 53

Query: 61  FHPYNTCITDLR-TSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLT 119
                      R  S W    ++    A  +++ EE   +  +   ++ +    VK ++ 
Sbjct: 54  IDHVRALTEMPRIASEWNRVFRQLPTEADIQEMYEEFEEILFAILPRYASPINAVKEVIA 113

Query: 120 ELRKEVRLLLLTNGDRQTQREKIEA-CACQSYF-DAVVVGGEQREEKPAPSIFYYCCNLL 177
            LR+    +  T G  +   + +    A Q Y  D +V   +    +P P + Y     L
Sbjct: 114 SLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMEL 173

Query: 178 GVQP-GDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPV-------------- 222
           GV P    + VGDT+ +D++ G NAG+     I  +  + L    V              
Sbjct: 174 GVYPMNHMIKVGDTV-SDMKEGRNAGMWTVGVILGSSELGLTEEEVENMDSVELREKIEV 232

Query: 223 ---------PHYMVSSVLELPALLQSID 241
                     H+ + ++ EL ++++ I+
Sbjct: 233 VRNRFVENGAHFTIETMQELESVMEHIE 260


>4RN3-A nrPDB
          Length = 213

 Score = 68.7 bits (166), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 42/200 (21%), Positives = 71/200 (35%), Gaps = 25/200 (12%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK--EEAEIICDKVQVKLSKECFHP 63
           ++AV +D D  + D+  A+      +++++      +  EE   I      +     F P
Sbjct: 11  IKAVIYDCDGVMFDSFEANLAFYQRIMEMMGRPRLSRDNEEQMRILHTYANREVLAHFFP 70

Query: 64  YNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRK 123
                       WEEA++   G    R+L            +  M + E  +  L  L+ 
Sbjct: 71  SPGD--------WEEAVR-CAGAIDYREL------------VPLMIMEEGFREALDTLKG 109

Query: 124 EVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
            V L + TN         +   +  SYF  V+        KP P          G+ P +
Sbjct: 110 RVGLGVCTNRSTSMDM-VLRLFSLDSYFSIVMTASRVTNPKPHPEPLLKVLEHFGIGPRE 168

Query: 184 CVMVGDTLETDIQGGLNAGL 203
            + VGD+ E D      AG+
Sbjct: 169 ALFVGDS-EVDRLSAEAAGV 187


>2HDO-A nrPDB
          Length = 209

 Score = 65.3 bits (157), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 34/235 (14%), Positives = 79/235 (33%), Gaps = 33/235 (14%)

Query: 7   RAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKY---HYKEEAEIICDKVQVKLSKECFHP 63
           +A+ FD+D TL ++  A    M EV+      +     ++   +  ++   +L       
Sbjct: 5   QALMFDIDGTLTNSQPAYTTVMREVLATYGKPFSPAQAQKTFPMAAEQAMTELG------ 58

Query: 64  YNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRK 123
                                  +       +   +  S   Q + L   + ++  +L  
Sbjct: 59  --------------------IAASEFDHFQAQYEDVMASHYDQ-IELYPGITSLFEQLPS 97

Query: 124 EVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
           E+RL ++T+  R      + +          +   +  + KP P         + V P +
Sbjct: 98  ELRLGIVTSQRRNELESGMRSYPFMMRMAVTISADDTPKRKPDPLPLLTALEKVNVAPQN 157

Query: 184 CVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
            + +GD++ +D Q    A +   + +   G+ P        +     L++  L +
Sbjct: 158 ALFIGDSV-SDEQTAQAANVDFGLAV--WGMDPNADHQKVAHRFQKPLDILELFK 209


>2HI0-A nrPDB
          Length = 240

 Score = 63.3 bits (152), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 43/213 (20%), Positives = 84/213 (39%), Gaps = 16/213 (7%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK-EEAE-IICDKVQVKLSKECFH 62
           + +A  FD+D T++DT+      +    +    ++ +  E+ +      V V +++   +
Sbjct: 3   KYKAAIFDMDGTILDTSADLTSALNYAFEQTGHRHDFTVEDIKNFFGSGVVVAVTRALAY 62

Query: 63  PYNTCITDLR--TSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL----AEDVKA 116
              +    L    +  E+  +       NR L      ++K     H  +       +  
Sbjct: 63  EAGSSRESLVAFGTKDEQIPEAVTQTEVNRVL-----EVFKPYYADHCQIKTGPFPGILD 117

Query: 117 MLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCN 175
           ++  LR K V+L +++N   +  +  +E       FD  +        KPAP +   C  
Sbjct: 118 LMKNLRQKGVKLAVVSNKPNEAVQVLVEEL-FPGSFDFALGEKSGIRRKPAPDMTSECVK 176

Query: 176 LLGVQPGDCVMVGDTLETDIQGGLNAGLKATVW 208
           +LGV    CV +GD+ E DIQ   N+ +     
Sbjct: 177 VLGVPRDKCVYIGDS-EIDIQTARNSEMDEIAV 208


>1TE2-A nrPDB
          Length = 226

 Score = 61.8 bits (148), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 39/205 (19%), Positives = 77/205 (37%), Gaps = 20/205 (9%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
           ++ A  FD+D  LID+     R  L+V+  L      + E       +++ +  + ++  
Sbjct: 8   QILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNELPDTL-GLRIDMVVDLWY-- 64

Query: 65  NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
                       +E ++     A +  L EE              L   V+  +   +++
Sbjct: 65  --ARQPWNGPSRQEVVERVIARAIS--LVEETR-----------PLLPGVREAVALCKEQ 109

Query: 125 VRLLLLTNGDRQTQREK-IEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
             L+ L +       EK +     +  FDA+    +    KP P ++  C   LGV P  
Sbjct: 110 GLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAKLGVDPLT 169

Query: 184 CVMVGDTLETDIQGGLNAGLKATVW 208
           CV + D++   +     A +++ V 
Sbjct: 170 CVALEDSV-NGMIASKAARMRSIVV 193


>3L5K-A nrPDB
          Length = 250

 Score = 57.6 bits (137), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 38/209 (18%), Positives = 66/209 (31%), Gaps = 34/209 (16%)

Query: 9   VFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCI 68
           + FD+D  L+DT         E+      KY +  ++ ++  K                 
Sbjct: 33  LIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKAL--------------- 77

Query: 69  TDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQ---HMTLAEDVKAMLTELRKEV 125
                    EA Q            EE     ++   +      L    + ++  LRK  
Sbjct: 78  ---------EAAQIIIDVLQLPMSKEELVEESQTKLKEVFPTAALMPGAEKLIIHLRKHG 128

Query: 126 RLLLLTNGDRQTQREKIEACACQ--SYFDAVVVGG--EQREEKPAPSIFYYCCNLLGVQP 181
               L    R    +   +   +  S F  +V+G   E +  KP P IF  C       P
Sbjct: 129 IPFALATSSRSASFDMKTSRHKEFFSLFSHIVLGDDPEVQHGKPDPDIFLACAKRFSPPP 188

Query: 182 --GDCVMVGDTLETDIQGGLNAGLKATVW 208
               C++  D     ++  L AG++  + 
Sbjct: 189 AMEKCLVFEDAP-NGVEAALAAGMQVVMV 216


>2C4N-A nrPDB
          Length = 250

 Score = 53.3 bits (126), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 8/116 (6%)

Query: 123 KEVRLLLLTNGDRQTQREKIEAC-ACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQP 181
                 + TN      R    AC A  +  + +         KP+P I     N +    
Sbjct: 135 ANGARFIATN-PDTHGRGFYPACGALCAGIEKISGRKPFYVGKPSPWIIRAALNKMQAHS 193

Query: 182 GDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPL---KSSPV-PHYMVSSVLEL 233
            + V+VGD L TDI  G  AGL+  + +  +G+  L    S P  P ++  SV E+
Sbjct: 194 EETVIVGDNLRTDILAGFQAGLETILVL--SGVSSLDDIDSMPFRPSWIYPSVAEI 247


>2X4D-A nrPDB
          Length = 271

 Score = 52.9 bits (125), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 48/264 (18%), Positives = 82/264 (31%), Gaps = 36/264 (13%)

Query: 3   LSRVRAVFFDLDNTLIDTAGAS--------------RRGMLEVIKLLQSKYHYKEEAEII 48
           L+ VR V  D+   L D+                  +R  L+V          + E    
Sbjct: 9   LAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESAASRAELVGQ 68

Query: 49  CDKVQVKLSKECFH---PYNTCITDLRTSH----WEEAIQETKGGAA----NRKLAEECY 97
             ++   +S++      P    I   R         + ++           N  +  +  
Sbjct: 69  LQRLGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAG 128

Query: 98  FLWKSTRLQHM--TLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVV 155
             +    + +    L E  K +L  L K       T+G        ++A        A V
Sbjct: 129 ESFSYQNMNNAFQVLMELEKPVLISLGKGRYYAA-TSGLMLDVGPYMKALEYACGIKAEV 187

Query: 156 VGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIV 215
           VG      KP+P  F      +GV+    VM+GD +  D+ G    G++A          
Sbjct: 188 VG------KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP 241

Query: 216 PLKSSP--VPHYMVSSVLELPALL 237
             +  P       V ++ E   LL
Sbjct: 242 SDEHHPEVKADGYVDNLAEAVDLL 265


>3QUB-A nrPDB
          Length = 243

 Score = 52.2 bits (123), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 33/212 (15%), Positives = 68/212 (32%), Gaps = 29/212 (13%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
           +++AV FD+D  L ++                  YH  E    +     + LS+E  + +
Sbjct: 23  KLKAVLFDMDGVLFNS----------------MPYH-SEAWHQVMKTHGLDLSREEAYMH 65

Query: 65  NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL--AEDVKAMLTELR 122
                    S      Q   G  A ++  E  Y         +           +L +++
Sbjct: 66  ---AGRTGASTINIVFQRELGKEATQEEIESIYHEKSILFNSYPEAERMPGAWELLQKVK 122

Query: 123 KEVRLLLLTNGDRQTQREKIEAC--ACQSYF--DAVVVGGEQREEKPAPSIFYYCCNLLG 178
            E    ++  G    Q   +E         F  + +V   + +  KP P  +       G
Sbjct: 123 SEGLTPMVVTGS--GQLSLLERLEHNFPGMFHKELMVTAFDVKYGKPNPEPYLMALKKGG 180

Query: 179 VQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
           ++  + V++ +     ++ G  AG+       
Sbjct: 181 LKADEAVVIENAP-LGVEAGHKAGIFTIAVNT 211


>1PW5-A nrPDB
          Length = 253

 Score = 51.4 bits (121), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 39/228 (17%), Positives = 73/228 (32%), Gaps = 20/228 (8%)

Query: 3   LSRVRAVFFDLDNT--LIDTAGASRRGMLEVIKLLQSKYHY--------KEEAEIICDKV 52
           L ++     D+D T  L D+        LE +K    ++ +         ++       +
Sbjct: 2   LDKIELFILDMDGTFYLDDSLLPGSLEFLETLKEKNKRFVFFTNNSSLGAQDYVRKLRNM 61

Query: 53  QVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAE 112
            V +  +          +     +        G    +K+ E    +        + L  
Sbjct: 62  GVDVPDDAVVTSGEITAEHMLKRFGRCRIFLLGTPQLKKVFEAYGHVIDEENPDFVVLGF 121

Query: 113 DVKAMLTELRKEVRLL------LLTNGDRQTQREKIEACACQSYFDAVVVGGEQR----E 162
           D       L+K   LL      + T+ D     ++       S   A+     ++     
Sbjct: 122 DKTLTYERLKKACILLRKGKFYIATHPDINCPSKEGPVPDAGSIMAAIEASTGRKPDLIA 181

Query: 163 EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
            KP P +        GV      MVGD L TD++ G NAG+ + + + 
Sbjct: 182 GKPNPLVVDVISEKFGVPKERMAMVGDRLYTDVKLGKNAGIVSILVLT 229


>3PDW-A nrPDB
          Length = 266

 Score = 50.2 bits (118), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 40/229 (17%), Positives = 66/229 (28%), Gaps = 19/229 (8%)

Query: 1   MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHY-------KEEAEIICDKVQ 53
           M L   +    DLD T+ +           V  L      Y           + + DK+ 
Sbjct: 1   MSLKTYKGYLIDLDGTMYNGTEKIEEACEFVRTLKDRGVPYLFVTNNSSRTPKQVADKLV 60

Query: 54  ---VKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTL 110
              +  ++E     +           ++A     G    R+  EE    +       + +
Sbjct: 61  SFDIPATEEQVFTTSMATAQHIAQQKKDASVYVIGEEGIRQAIEENGLTFGGENADFVVV 120

Query: 111 AEDVKAMLTELR------KEVRLLLLTNGDRQTQREKIEACA---CQSYFDAVVVGGEQR 161
             D      +        +     + TNGD     E+          S            
Sbjct: 121 GIDRSITYEKFAVGCLAIRNGARFISTNGDIAIPTERGLLPGNGSLTSVLTVSTGVQPVF 180

Query: 162 EEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
             KP   I      +LG    + +MVGD   TDI  G+NAG+   +   
Sbjct: 181 IGKPESIIMEQAMRVLGTDVSETLMVGDNYATDIMAGINAGMDTLLVHT 229


>3NUQ-A nrPDB
          Length = 282

 Score = 48.3 bits (113), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 50/246 (20%), Positives = 89/246 (36%), Gaps = 32/246 (13%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           ++  FFD+DN L  ++      M + I                  +  +KLS E  H  N
Sbjct: 57  LKVFFFDIDNCLYKSSTRIHDLMQQSILRFF--------------QTHLKLSPEDAHVLN 102

Query: 66  TCITDLRTSHWEEAIQETKGGAA-NRKLAEECYFLWKSTRLQHMTLAEDVK--AMLTELR 122
                   S+++E     +G    ++  A E   L   +      L  D+    ML  LR
Sbjct: 103 -------NSYYKEYGLAIRGLVMFHKVNALEYNRLVDDSLPLQDILKPDIPLRNMLLRLR 155

Query: 123 KEVR---LLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREE----KPAPSIFYYCCN 175
           +  +   L L TN  +      +        FD +      R +    KP    F     
Sbjct: 156 QSGKIDKLWLFTNAYKNHAIRCLRLLGIADLFDGLTYCDYSRTDTLVCKPHVKAFEKAMK 215

Query: 176 LLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVP-LKSSPVPHYMVSSVLELP 234
             G+   +     D    +I+ G+  G+K  + + +N +   L  +P    ++S +LELP
Sbjct: 216 ESGLARYENAYFIDDSGKNIETGIKLGMKTCIHLVENEVNEILGQTPEGAIVISDILELP 275

Query: 235 ALLQSI 240
            ++  +
Sbjct: 276 HVVSDL 281


>4Y2Y-A nrPDB
          Length = 561

 Score = 46.8 bits (109), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 39/243 (16%), Positives = 85/243 (34%), Gaps = 30/243 (12%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           +RA  FDLD  L   A     G              + E  +   +  +  + +   P  
Sbjct: 3   LRAAVFDLDGVLALPAVFGVLG--------------RTEEALALPRGLLNDAFQKGGPEG 48

Query: 66  TCITDLRT----SHW----EEAIQETKGGAANRKLAEEC--YFLWKSTRLQHMTLAEDVK 115
                ++     S W    EE  ++    A    L +      ++             ++
Sbjct: 49  ATTRLMKGEITLSQWIPLMEENCRKCSETA-KVCLPKNFSIKEIFDKAISARKINRPMLQ 107

Query: 116 AMLTELRKEVRLLLLTNG--DRQTQREKIEACACQ--SYFDAVVVGGEQREEKPAPSIFY 171
           A L   +K     +LTN   D + +R+ +    C+   +FD ++   +    KP P I+ 
Sbjct: 108 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 167

Query: 172 YCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVL 231
           +  + L   P + V + D +  +++   + G+   +  + +  +          ++++  
Sbjct: 168 FLLDTLKASPSEVVFLDD-IGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPA 226

Query: 232 ELP 234
            LP
Sbjct: 227 PLP 229


>4PNH-A nrPDB
          Length = 199

 Score = 45.2 bits (105), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 1/61 (1%)

Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVP 223
           KP P +         + P D  +VGD+L  D+Q G   G +  + +   G   L +  +P
Sbjct: 119 KPMPGMMKLIAERFEIDPADTPVVGDSLR-DLQAGAALGFRPHLVLTGKGKKTLAAGGLP 177

Query: 224 H 224
            
Sbjct: 178 E 178


>2B0C-A nrPDB
          Length = 206

 Score = 44.5 bits (103), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 42/223 (18%), Positives = 77/223 (34%), Gaps = 38/223 (17%)

Query: 10  FFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCIT 69
            FDL N ++D       G    +                  ++ +   K+ FH       
Sbjct: 11  IFDLGNVIVDIDFNRVLGAWSDLT-----------------RIPLASLKKSFHMGEAFHQ 53

Query: 70  DLRTSHWEEAIQETK-GGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV-RL 127
             R    +EA  E      A     E+    W++     + L  +V A++ +LR++  R+
Sbjct: 54  HERGEISDEAFAEALCHEMALPLSYEQFSHGWQAV---FVALRPEVIAIMHKLREQGHRV 110

Query: 128 LLLTNGDRQT----QREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD 183
           ++L+N +R        E  E        D + +  +    KP   I+ +     G  P D
Sbjct: 111 VVLSNTNRLHTTFWPEEYPEIRDAA---DHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD 167

Query: 184 CVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYM 226
            V   D  +  I+G    G+ + +  +K          +P Y 
Sbjct: 168 TVFFDDNADN-IEGANQLGITSILVKDKT--------TIPDYF 201


>1CR6-A nrPDB
          Length = 554

 Score = 43.3 bits (100), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 35/234 (14%), Positives = 81/234 (34%), Gaps = 12/234 (5%)

Query: 6   VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
           +R   FDLD  L   + A      E    L   +          +    +L K     ++
Sbjct: 3   LRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKI-TFS 61

Query: 66  TCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEV 125
             +  +  S+ + +         N  +++       +  +    L    +A +   +K  
Sbjct: 62  QWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPML----QAAIALKKKGF 117

Query: 126 RLLLLTN-----GDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
              ++TN     GD++    ++  C    +FD ++   +    KP P I+ +  + L  +
Sbjct: 118 TTCIVTNNWLDDGDKRDSLAQM-MCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAK 176

Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELP 234
           P + V + D   ++++   + G+   +  N    +             + L +P
Sbjct: 177 PNEVVFLDD-FGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP 229


>4JB3-A nrPDB
          Length = 228

 Score = 42.5 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 38/209 (18%), Positives = 67/209 (32%), Gaps = 28/209 (13%)

Query: 4   SRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHP 63
           S ++ + FD    ++D            + L         +A+   DK         +H 
Sbjct: 22  SMIKNIVFDFGGVIVDIDRDKAVQAFIKLGL--------ADADTRLDK---------YHQ 64

Query: 64  YNTCITDLRTSHWEEAIQETKGGAANRKLA-EECYFLWKSTRLQHMTLAEDVKAMLTELR 122
                         +  ++  G    R+L  EE    W     +       +  +L  LR
Sbjct: 65  TGIFQELEEGKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNE--VDLRKLDYIL-GLR 121

Query: 123 KEVRLLLLTNGD------RQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNL 176
           K   + LL+N +        +     E      Y D + +  +    KPAP IF +    
Sbjct: 122 KSYHVYLLSNTNPFVMSWACSPEFSSEGKPLNDYCDKLYLSYQLGHTKPAPEIFDFMIKD 181

Query: 177 LGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
             V P + + V D   ++I  G   G + 
Sbjct: 182 SHVIPSETLFVDD-GSSNIHIGKELGFET 209


>3L8F-A nrPDB
          Length = 187

 Score = 42.5 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 31/162 (19%), Positives = 60/162 (37%), Gaps = 27/162 (16%)

Query: 103 TRLQHMTLAEDVKAMLTELRK-EVRLLLLTNGD-------RQTQREKIEACACQSYFDAV 154
             + +    + V   + EL+K    L+++TN          + Q E +      S  D  
Sbjct: 24  HEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRD 83

Query: 155 VVGG--------------EQRE----EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQ 196
           V                 E R+     KP P +     + L +      MVGD LE D+Q
Sbjct: 84  VDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLE-DMQ 142

Query: 197 GGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
             + A +   V +     +  ++     ++++S+ +LP  ++
Sbjct: 143 AAVAANVGTKVLVRTGKPITPEAENAADWVLNSLADLPQAIK 184


>3L1U-A nrPDB
          Length = 211

 Score = 42.5 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 31/162 (19%), Positives = 60/162 (37%), Gaps = 27/162 (16%)

Query: 103 TRLQHMTLAEDVKAMLTELRK-EVRLLLLTNGD-------RQTQREKIEACACQSYFDAV 154
             + +    + V   + EL+K    L+++TN          + Q E +      S  D  
Sbjct: 44  HEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRD 103

Query: 155 VVGG--------------EQRE----EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQ 196
           V                 E R+     KP P +     + L +      MVGD LE D+Q
Sbjct: 104 VDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLE-DMQ 162

Query: 197 GGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
             + A +   V +     +  ++     ++++S+ +LP  ++
Sbjct: 163 AAVAANVGTKVLVRTGKPITPEAENAADWVLNSLADLPQAIK 204


>2O2X-A nrPDB
          Length = 218

 Score = 40.6 bits (93), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 4/94 (4%)

Query: 150 YFDAVVVGGEQRE---EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKAT 206
           Y +A V      +    KP P +       L +     ++VGD L  D+Q G  AGL   
Sbjct: 120 YHEAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVGDKL-ADMQAGKRAGLAQG 178

Query: 207 VWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
             ++    V    +  P    S + +L A ++++
Sbjct: 179 WLVDGEAAVQPGFAIRPLRDSSELGDLLAAIETL 212


>4I9G-A nrPDB
          Length = 361

 Score = 38.3 bits (87), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/101 (22%), Positives = 38/101 (37%), Gaps = 6/101 (5%)

Query: 113 DVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAV---VVGGEQREEKPAPSI 169
           D+      +R    L +  N D     E+       S   A+        +   KPAP++
Sbjct: 141 DLAEAALAIRAGA-LWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPAL 199

Query: 170 FYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
                          ++VGD L+TDI+G   AGL + + + 
Sbjct: 200 MTEAVAR--GDFRAALVVGDRLDTDIEGANAAGLPSLMVLT 238


>2HO4-A nrPDB
          Length = 259

 Score = 36.8 bits (83), Expect = 0.010,   Method: Composition-based stats.
 Identities = 46/253 (18%), Positives = 84/253 (33%), Gaps = 42/253 (16%)

Query: 6   VRAVFFDLDNTL--IDTAGASRRGMLEVIKLLQSKYHY--------KEEAEIICDKVQVK 55
           ++AV  DL+ TL   D A    +  L+ ++       +        K++      K++ +
Sbjct: 7   LKAVLVDLNGTLHIEDAAVPGAQEALKRLRATSVMVRFVTNTTKETKKDLLERLKKLEFE 66

Query: 56  LSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVK 115
           +S++      T +T  R    ++ ++       +R L E   F    T+  +  +     
Sbjct: 67  ISEDEIF---TSLTAARNLIEQKQVRPML-LLDDRALPE---FTGVQTQDPNAVVIGLAP 119

Query: 116 AML--TELRKEVRLLL---------------LTNGDRQTQREKIEACACQSYFDAVVVGG 158
                  L +  RLLL                 +G        + A    +   A+VVG 
Sbjct: 120 EHFHYQLLNQAFRLLLDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKAMVVG- 178

Query: 159 EQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLK 218
                KP  + F          P + VM+GD    D+ G  N G+   +          +
Sbjct: 179 -----KPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGMLGILVKTGKYKAADE 233

Query: 219 SS--PVPHYMVSS 229
               P P+    S
Sbjct: 234 EKINPPPYLTCES 246


>3L8H-A nrPDB
          Length = 179

 Score = 36.4 bits (82), Expect = 0.011,   Method: Composition-based stats.
 Identities = 16/61 (26%), Positives = 22/61 (36%), Gaps = 1/61 (1%)

Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVP 223
           KP P ++        V       VGD+L  D+Q    AG    +    NG   L    +P
Sbjct: 101 KPLPGMYRDIARRYDVDLAGVPAVGDSLR-DLQAAAQAGCAPWLVQTGNGRKTLAQGGLP 159

Query: 224 H 224
            
Sbjct: 160 E 160


>1U7O-A nrPDB
          Length = 164

 Score = 36.0 bits (81), Expect = 0.015,   Method: Composition-based stats.
 Identities = 21/102 (20%), Positives = 33/102 (32%), Gaps = 11/102 (10%)

Query: 101 KSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDR--QTQREKIEACACQSYFDAVVVGG 158
           +  R Q++ L  +V  +L  L+     +   +     Q   + +E      YF       
Sbjct: 38  RDRRGQNIQLYPEVPEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLGKYFI------ 91

Query: 159 EQREEKPAPSI--FYYCCNLLGVQPGDCVMVGDTLETDIQGG 198
            QRE  P   +  F    +  GV     V   D     I  G
Sbjct: 92  -QREIYPGSKVTHFERLHHKTGVPFSQMVFFDDENRNIIDVG 132


>3HLT-A nrPDB
          Length = 266

 Score = 36.0 bits (81), Expect = 0.016,   Method: Composition-based stats.
 Identities = 15/69 (21%), Positives = 25/69 (36%), Gaps = 2/69 (2%)

Query: 163 EKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSS-- 220
            KP  + F       G +P + VM+GD    D+ G  + G+   +          +    
Sbjct: 178 GKPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKIN 237

Query: 221 PVPHYMVSS 229
           P P+    S
Sbjct: 238 PPPYLTCES 246


>2QLT-A nrPDB
          Length = 275

 Score = 35.2 bits (79), Expect = 0.030,   Method: Composition-based stats.
 Identities = 35/194 (18%), Positives = 65/194 (33%), Gaps = 34/194 (17%)

Query: 5   RVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPY 64
           ++ A  FD+D T+I +  A      +  K    K ++  E       + +      +   
Sbjct: 34  KINAALFDVDGTIIISQPAIAAFWRDFGK---DKPYFDAE-----HVIHISHGWRTYDAI 85

Query: 65  NTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
                D      EE + +   G    K  E    +  + +L +          L  L KE
Sbjct: 86  AKFAPDFAD---EEYVNK-LEGEIPEKYGEHSIEVPGAVKLCNA---------LNALPKE 132

Query: 125 VRLLLLTNGDRQTQREKIEACACQS--YFDAVVVGGEQREEKPAPSIFYYCCNLLGV--- 179
            +  + T+G R   ++  +    +   YF   +   + ++ KP P  +    N LG    
Sbjct: 133 -KWAVATSGTRDMAKKWFDILKIKRPEYF---ITANDVKQGKPHPEPYLKGRNGLGFPIN 188

Query: 180 --QP--GDCVMVGD 189
              P     V+  D
Sbjct: 189 EQDPSKSKVVVFED 202


>5YA1-A nrPDB
          Length = 540

 Score = 32.9 bits (73), Expect = 0.14,   Method: Composition-based stats.
 Identities = 11/49 (22%), Positives = 20/49 (40%)

Query: 2  GLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICD 50
          G   +RAV FDL+   I    A  R +         ++   +  ++ C+
Sbjct: 30 GTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACE 78


>3IRU-A nrPDB
          Length = 277

 Score = 32.1 bits (71), Expect = 0.21,   Method: Composition-based stats.
 Identities = 41/202 (20%), Positives = 67/202 (33%), Gaps = 33/202 (16%)

Query: 71  LRTSHWEEAIQETKGGAANRKLAEECYFLW----KSTRLQHMTLAEDVKAMLTELRKEVR 126
           L  S    A    KG A+N +  +  Y L+         Q   L    K +  +L  +  
Sbjct: 69  LGNSRIANAWLSIKGQASNEEDIKRLYDLFAPIQTRIVAQRSQLIPGWKEVFDKLIAQGI 128

Query: 127 LLLLTNGDRQTQR-EKIEACACQSYFDA-VVVGGEQREEKPAPSIFYYCCNLLGV-QPGD 183
            +    G         + A   Q Y  A  V   +    +P P +       L V     
Sbjct: 129 KVGGNTGYGPGMMAPALIAAKEQGYTPASTVFATDVVRGRPFPDMALKVALELEVGHVNG 188

Query: 184 CVMVGDTLETDIQGGLNAGLKATVWINKNG-----------IVPLKSSPV---------- 222
           C+ V DTL   I+ GL AG+  TV ++ +G            +                 
Sbjct: 189 CIKVDDTL-PGIEEGLRAGM-WTVGVSCSGNEVGLDREDWQALSSDEQQSYRQHAEQRLF 246

Query: 223 ---PHYMVSSVLELPALLQSID 241
               HY++ SV +L  ++  ++
Sbjct: 247 NAGAHYVIDSVADLETVITDVN 268


>6GRI-C nrPDB
          Length = 272

 Score = 30.2 bits (66), Expect = 0.91,   Method: Composition-based stats.
 Identities = 16/82 (19%), Positives = 27/82 (32%), Gaps = 7/82 (8%)

Query: 134 DRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGD------CVM- 186
                 E +  C  QS + ++  G  +R  KP  ++ Y       +           +M 
Sbjct: 154 PLSQALEPVATCNTQSLYRSLSGGDSERLGKPHFALVYCIIFEKALFKYRYRGYRMALME 213

Query: 187 VGDTLETDIQGGLNAGLKATVW 208
            G   +  +      GLK  VW
Sbjct: 214 TGSMYQNAVLVADQIGLKNRVW 235


>2WM8-A nrPDB
          Length = 187

 Score = 29.8 bits (65), Expect = 1.2,   Method: Composition-based stats.
 Identities = 16/97 (16%), Positives = 27/97 (27%), Gaps = 11/97 (11%)

Query: 101 KSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDR--QTQREKIEACACQSYFDAVVVGG 158
           +  R Q + L  +V  +L  L+         +     +   + +E      YF       
Sbjct: 60  RDRRGQDVRLYPEVPEVLKRLQSLGVPGAAASRTSEIEGANQLLELFDLFRYFV------ 113

Query: 159 EQREEKPAPSI--FYYCCNLLGVQPGDCVMVGDTLET 193
             RE  P   I  F       G+     +   D    
Sbjct: 114 -HREIYPGSKITHFERLQQKTGIPFSQMIFFDDERRN 149


>1PZ1-A nrPDB
          Length = 333

 Score = 29.4 bits (64), Expect = 1.5,   Method: Composition-based stats.
 Identities = 24/125 (19%), Positives = 46/125 (36%), Gaps = 12/125 (9%)

Query: 3   LSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFH 62
           +  +RA   D   TLIDTA A   G  E I     K + K +  I+  K  +        
Sbjct: 37  IETIRAAL-DQGITLIDTAPAYGFGQSEEIVGKAIKEYMKRDQVILATKTALDWKNNQLF 95

Query: 63  PYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELR 122
                    R ++    ++E +     ++L  +   L++      +   E+   ++ EL 
Sbjct: 96  ---------RHANRARIVEEVENSL--KRLQTDYIDLYQVHWPDPLVPIEETAEVMKELY 144

Query: 123 KEVRL 127
              ++
Sbjct: 145 DAGKI 149


>3WDH-A nrPDB
          Length = 710

 Score = 27.9 bits (60), Expect = 4.0,   Method: Composition-based stats.
 Identities = 13/67 (19%), Positives = 23/67 (34%), Gaps = 2/67 (2%)

Query: 54  VKLSKECFH-PYNTCITDLRTSH-WEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLA 111
            K  +  ++ P      D      WEE ++E       RK      FL      +HM   
Sbjct: 576 KKGVENSYNSPDEVNQVDWNEKSRWEEDVREIMKLIELRKKHGAFRFLTADQVRRHMKFY 635

Query: 112 EDVKAML 118
           +   +++
Sbjct: 636 DTHPSVI 642


>5MSN-A nrPDB
          Length = 293

 Score = 27.9 bits (60), Expect = 4.1,   Method: Composition-based stats.
 Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 6/71 (8%)

Query: 61  FHPYNTCITDLRTSHW---EEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAM 117
           F P +  I  LR  H+   ++ +Q            E    L++   LQ     ED+K +
Sbjct: 204 FFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFR---LQSQWDLEDIKPL 260

Query: 118 LTELRKEVRLL 128
           + EL      +
Sbjct: 261 IEELNSRGMKI 271


>5OKI-C nrPDB
          Length = 380

 Score = 27.5 bits (59), Expect = 4.9,   Method: Composition-based stats.
 Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 6/71 (8%)

Query: 61  FHPYNTCITDLRTSHW---EEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAM 117
           F P +  I  LR  H+   ++ +Q            E    L++   LQ     ED+K +
Sbjct: 291 FFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFR---LQSQWDLEDIKPL 347

Query: 118 LTELRKEVRLL 128
           + EL      +
Sbjct: 348 IEELNSRGMKI 358


>2LEF-A nrPDB
          Length = 86

 Score = 27.1 bits (58), Expect = 7.7,   Method: Composition-based stats.
 Identities = 11/37 (29%), Positives = 14/37 (37%), Gaps = 3/37 (8%)

Query: 79  AIQETKGGAANRKLAEE---CYFLWKSTRLQHMTLAE 112
           AI +  G   +    EE    Y L +  R  HM L  
Sbjct: 32  AINQILGRRWHALSREEQAKYYELARKERQLHMQLYP 68


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.310    0.118    0.280 

Lambda     K      H
   0.267   0.0358    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,314,678
Number of Sequences: 36641
Number of extensions: 241281
Number of successful extensions: 867
Number of sequences better than 10.0: 49
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 766
Number of HSP's gapped (non-prelim): 92
length of query: 248
length of database: 10,336,785
effective HSP length: 95
effective length of query: 153
effective length of database: 6,855,890
effective search space: 1048951170
effective search space used: 1048951170
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 57 (26.8 bits)