BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8NHX9 (752 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6NQ0-A nrPDB 1522 0.0 5E1J-A nrPDB 164 1e-40 6C96-A nrPDB 151 8e-37 5HVD-A nrPDB 50 5e-06 4LTR-A nrPDB 44 2e-04 5HKD-A nrPDB 44 3e-04 6DU8-A nrPDB 44 4e-04 5Z1W-A nrPDB 42 7e-04 4DXW-A nrPDB 42 0.001 3RVY-A nrPDB 40 0.004 3WKV-A nrPDB 37 0.023 5EK0-A nrPDB 37 0.024 6N4I-A nrPDB 37 0.028 4G7Y-S nrPDB 37 0.044 4BGN-A nrPDB 35 0.17 4G80-S nrPDB 33 0.62 6E2G-A nrPDB 31 2.1 6BOA-A nrPDB 30 3.5 5T5I-A nrPDB 29 6.0 4F4L-A nrPDB 29 6.4 >6NQ0-A nrPDB Length = 756 Score = 1522 bits (3940), Expect = 0.0, Method: Compositional matrix adjust. Identities = 748/752 (99%), Positives = 748/752 (99%) Query: 1 MAEPQAESEPLLGGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR 60 MAEPQAESEP GGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR Sbjct: 5 MAEPQAESEPAAGGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR 64 Query: 61 SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP 120 SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP Sbjct: 65 SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP 124 Query: 121 PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC 180 PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC Sbjct: 125 PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC 184 Query: 181 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG 240 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG Sbjct: 185 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG 244 Query: 241 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS 300 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS Sbjct: 245 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS 304 Query: 301 LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ 360 LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ Sbjct: 305 LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ 364 Query: 361 NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP 420 NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP Sbjct: 365 NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP 424 Query: 421 FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY 480 FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY Sbjct: 425 FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY 484 Query: 481 LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL 540 LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL Sbjct: 485 LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL 544 Query: 541 WDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL 600 WDMTRMLNMLIVFRFLRIIPSMK MAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL Sbjct: 545 WDMTRMLNMLIVFRFLRIIPSMKPMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL 604 Query: 601 FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD 660 FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD Sbjct: 605 FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD 664 Query: 661 AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM 720 AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM Sbjct: 665 AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM 724 Query: 721 TVELLFRDILEEPGEDELTERLSQHPHLWLCR 752 TVELLFRDILEEP EDELTERLSQHPHLWLCR Sbjct: 725 TVELLFRDILEEPEEDELTERLSQHPHLWLCR 756 >5E1J-A nrPDB Length = 741 Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 186/748 (24%), Positives = 326/748 (43%), Gaps = 122/748 (16%) Query: 8 SEPLLGGARGGGGDWPAGLTTYRSIQVGPG-----AAARWDLCIDQAVVFIEDAIQYRSI 62 +PL+G GGG RS + G AAA DL D + +E Sbjct: 2 EDPLIGRDSLGGG---GTDRVRRSEAITHGTPFQKAAALVDLAEDGIGLPVE-------- 50 Query: 63 NHRVDASSMWLYRRYYSNVCQRTL--SFTIFLILFLAFIETP-----SSLTSTADVRYRA 115 +D SS RYY + L S F +LFL F E P + S D Y Sbjct: 51 --ILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYY 108 Query: 116 APWEPPCGLTESV--EVLCLLVFAAD----LSVKGYLFGWAHFQKNLWLLGYLVVLVVSL 169 P ES+ EV+ L + +S +G W + NL + +V+L V + Sbjct: 109 LGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTS-RLNLVKVACVVILFVDV 167 Query: 170 VDWTVSLSLVCHE--PLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHL 227 + + LS + + P RI +R + + ++ TL + L ++ L + L Sbjct: 168 LVDFLYLSPLAFDFLPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFL 227 Query: 228 CLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRA 287 + ++F +Q LT F + +L + +L TT+NNPDV IPAY +R Sbjct: 228 LFASWIAFVMFEDTQQG-------LTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRW 280 Query: 288 YAIFFIVFTVIGSLFLMNLLTAIIYSQFRGYLMKSLQ-TSLFRRRLGTRAAFEVLSSMVG 346 ++FF+++ +IG F+ NL+ A++Y F+ L K + +RR+ +A + S G Sbjct: 281 SSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNG 340 Query: 347 EGGAFPQAVGVKPQNLLQVLQKVQLDSSHKQAMMEKVRSYGSV-LLSAEEFQKLFNELDR 405 E +D + + E++ +Y ++ +S EEF +F+ELD Sbjct: 341 E-----------------------IDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDD 377 Query: 406 S--------------------VVKEHPPR-----PE-YQSPFLQSAQFLFGHYYFDYLGN 439 + KE P P+ Y S Q + F Y + Sbjct: 378 TRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAIS 437 Query: 440 LIALANLVSICVFLVLDADVLPAER----DDFILGILNCVFIVYYLLEMLLKVFALGLRG 495 I + N +++ V LD + A++ +F+ G + Y+LEM LK++ G Sbjct: 438 FILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWI-------YVLEMALKIYTYGFEN 490 Query: 496 YLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIVFRF 555 Y +N FD L+T V+++ E +T P+ S + R L + + R Sbjct: 491 YWREGANRFDFLVTWVIVIGETATFIT---------PDENTFFSNGEWIRYLLLARMLRL 541 Query: 556 LRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLA 615 +R++ +++ +T + L+ ++ + G + V ++ IG+ +F G++ A GN L Sbjct: 542 IRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNA--GNKKLF 599 Query: 616 PANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGP-WSKIYF 674 + +Y NF+D+ +VTL+NL+V+ NWQV++++Y+ +G WS YF Sbjct: 600 ET-------ELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYF 652 Query: 675 VLWWLVSSVIWVNLFLALILENFLHKWD 702 V +++++ ++ +NL +A +LE F + D Sbjct: 653 VSFYVITILLLLNLVVAFVLEAFFTELD 680 >6C96-A nrPDB Length = 825 Score = 151 bits (382), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 160/598 (26%), Positives = 271/598 (45%), Gaps = 66/598 (11%) Query: 127 SVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRI 186 ++E+ L+V +L +K G+ F ++ + VLVV ++ V L +R+ Sbjct: 143 TLELFALMVVVFELCMKLRWLGFHTFVRHKRTMVKTSVLVVQFIEAIVVLVRQTSH-VRV 201 Query: 187 RRLLRPFFLL--QNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQD 244 R LR FL+ + +++ L+ I SLP + LLL + +F + G LF+ D Sbjct: 202 TRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFSTNPSD 261 Query: 245 DGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLM 304 YF L S+ +L VLLTTAN PDVM+P+YS+N +FFIV+ I F+M Sbjct: 262 P--------YFSTLENSIVNLFVLLTTANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIM 313 Query: 305 NLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGG-AFPQAVGVKPQNLL 363 NLL A+++ F ++ L +R + A+ +L+S G ++ Q G L Sbjct: 314 NLLLAVVFDTFNDIEKHKFKSLLLHKRTAIQHAYGLLASQRRPAGISYRQFEG------L 367 Query: 364 QVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFN--------ELDRSVVKEHPPRP 415 K ++ + + + + + LLS ++F ++ + +R + PR Sbjct: 368 MRFYKPRMSARERFLTFKALNQSNTPLLSLKDFYDIYEVAALQWKAKRNRQHWFDELPRT 427 Query: 416 EYQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICV--FLVLDADVLPAERDDFILGILN 473 + + L F Y L+ N V I V F++ + L Sbjct: 428 AFL--IFKGINILVNSKAFQYFMYLVVAVNGVWILVETFMLKGGNFTSKHVPWSYL---- 481 Query: 474 CVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPE 533 VF+ Y +E+ +KV LG YLS N+FD +T Sbjct: 482 -VFLTIYGVELFMKVAGLGPVEYLSSGWNLFDFSVTAFAF-------------------- 520 Query: 534 MVGLLSLWDMTRMLNMLIVFR---FLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVY 590 +GLL+L ++V R LR+ K V T+ L+ M + G L+ Y Sbjct: 521 -LGLLALTLNMEPFYFIVVLRPLQLLRLFKLKKRYRNVLDTMFELLPRMASLGLTLLTFY 579 Query: 591 YVFAIIGINLFRGVIVALPGN-SSLAPANG--SAPCGSFEQLE---YWANNFDDFAAALV 644 Y FAI+G+ F G + N S++A A + G+ ++E Y+ NNFD+ + V Sbjct: 580 YSFAIVGMEFFNGRLTPNCCNTSTVADAYRFINHTVGNKTKVEEGYYYLNNFDNILNSFV 639 Query: 645 TLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWD 702 TL+ L VVNNW + ++ + WS++YF+ +++V+ V+ + + +A ILE F+ + + Sbjct: 640 TLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVV-MTIIVAFILEAFVFRMN 696 >5HVD-A nrPDB Length = 277 Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 46/189 (24%), Positives = 92/189 (48%), Gaps = 15/189 (7%) Query: 123 GLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHE 182 L E V+ LCL +F ++S+K Y +G F ++ W L V++ ++L+ SLS+ Sbjct: 46 NLLERVDQLCLTIFIVEISLKIYAYGVRGFFRSGWNLFDFVIVAIALMPAQGSLSV---- 101 Query: 183 PLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGK 242 LR R+ R L+ M++ ++ + +LP + SV LL + + + L+ Sbjct: 102 -LRTFRIFRVMRLVSVIPTMRRVVQGMLLALPGVGSVAALLTVVFYIAAVMATNLYGATF 160 Query: 243 QDDGQDRERLTYFQNLPESLTSLLVLLTTAN-NPDVMIPAYSKNRAYAIFFIVFTVIGSL 301 + +F +L +SL +L ++T + + ++ P + + +FFI F ++ + Sbjct: 161 PE---------WFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTF 211 Query: 302 FLMNLLTAI 310 ++NL I Sbjct: 212 TVLNLFIGI 220 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 44/216 (20%), Positives = 97/216 (44%), Gaps = 51/216 (23%) Query: 480 YLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLS 539 +++E+ LK++A G+RG+ N+FD ++ + L+ +L+V Sbjct: 59 FIVEISLKIYAYGVRGFFRSGWNLFDFVIVAIALMPAQGSLSVL---------------- 102 Query: 540 LWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGIN 599 R + V R + +IP+M+ VV +L L + + +L VV+Y+ A++ N Sbjct: 103 -----RTFRIFRVMRLVSVIPTMR--RVVQGMLLAL-PGVGSVAALLTVVFYIAAVMATN 154 Query: 600 LFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFL 659 L+ +F + W F D + +L TL+ +M + +W + + Sbjct: 155 LY---------------------GATFPE---W---FGDLSKSLYTLFQVMTLESWSMGI 187 Query: 660 DAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILE 695 P + ++F+ + ++++ +NLF+ + ++ Sbjct: 188 VRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGICVD 223 >4LTR-A nrPDB Length = 152 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 33/124 (26%) Query: 579 MRAFGGI------LVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYW 632 +RA GI L+V++YVFA++G LF SF + W Sbjct: 8 LRAIPGIAWIALLLLVIFYVFAVMGTKLF---------------------AQSFPE---W 43 Query: 633 ANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLAL 692 F A++ TL+ +M + +W + + + PW+ IYFV + LVSS +NLF+ + Sbjct: 44 ---FGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGI 100 Query: 693 ILEN 696 I+E+ Sbjct: 101 IIES 104 >5HKD-A nrPDB Length = 152 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 33/124 (26%) Query: 579 MRAFGGI------LVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYW 632 +RA GI L+V++YVFA++G LF SF + W Sbjct: 8 LRAIPGIAWIALLLLVIFYVFAVMGTKLF---------------------AQSFPE---W 43 Query: 633 ANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLAL 692 F A++ TL+ +M + +W + + + PW+ IYFV + LVSS +NLF+ + Sbjct: 44 ---FGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGI 100 Query: 693 ILEN 696 I+E+ Sbjct: 101 IIES 104 >6DU8-A nrPDB Length = 805 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 45/156 (28%), Positives = 74/156 (47%), Gaps = 24/156 (15%) Query: 465 DDFILG--ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLL--------- 513 D FI+G ++ CVFI YY++E +L++ LR YLS N+ D L V+LL Sbjct: 349 DFFIVGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILD--LVVILLSIVAVGFHI 405 Query: 514 --VLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLM 565 LE++ L L P + L+ W T+ NM V + + I K M Sbjct: 406 FRTLEVNRLMGKLLQQPNTYADFE-FLAFW-QTQYNNMNAVNLFFAWIKIFKYISFNKTM 463 Query: 566 AVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLF 601 ++ST+ +++ F + +V++ +A +G LF Sbjct: 464 TQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLF 499 >5Z1W-A nrPDB Length = 566 Score = 42.4 bits (98), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 45/156 (28%), Positives = 74/156 (47%), Gaps = 24/156 (15%) Query: 465 DDFILG--ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLL--------- 513 D FI+G ++ CVFI YY++E +L++ LR YLS N+ D L V+LL Sbjct: 286 DFFIVGCEVVFCVFIFYYVVEEILEIHLHRLR-YLSSVWNILD--LVVILLSIVAVGFHI 342 Query: 514 --VLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLM 565 LE++ L L P + L+ W T+ NM V + + I K M Sbjct: 343 FRTLEVNRLMGKLLQQPDTYADF-EFLAFW-QTQYNNMNAVNLFFAWIKIFKYISFNKTM 400 Query: 566 AVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLF 601 ++ST+ +++ F + +V++ +A +G LF Sbjct: 401 TQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLF 436 >4DXW-A nrPDB Length = 229 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/162 (28%), Positives = 81/162 (50%), Gaps = 12/162 (7%) Query: 150 AHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCI 209 A F K+ W + V++ +SL+ + S + LRI R+LR L+ +K+ ++ I Sbjct: 70 ADFFKSGWNIFDTVIVAISLIPIPNNSSFLVLRLLRIFRVLR---LISVIPELKQIIEAI 126 Query: 210 RWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLL 269 S+ + V LLL I L ++ G +LF G D + + +L SL +L +L Sbjct: 127 LESVRRVFFVSLLLFIILYIYATMGAILF--GNDDPSR-------WGDLGISLITLFQVL 177 Query: 270 TTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAII 311 T ++ VM+P ++F F +I S+ ++NL+ AI+ Sbjct: 178 TLSSWETVMLPMQEIYWWSWVYFFSFIIICSITILNLVIAIL 219 Score = 33.1 bits (74), Expect = 0.46, Method: Compositional matrix adjust. Identities = 34/156 (21%), Positives = 73/156 (46%), Gaps = 30/156 (19%) Query: 546 MLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVI 605 +L +L +FR LR+I + + + +L V+ + +L ++ Y++A +G LF Sbjct: 100 VLRLLRIFRVLRLISVIPELKQIIEAILESVRRVFFVSLLLFIILYIYATMGAILF---- 155 Query: 606 VALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQ-VFLDAYRR 664 GN + + D +L+TL+ ++ +++W+ V L Sbjct: 156 ----GNDD-------------------PSRWGDLGISLITLFQVLTLSSWETVMLPMQEI 192 Query: 665 YSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHK 700 Y WS +YF + ++ S+ +NL +A++++ + K Sbjct: 193 YW--WSWVYFFSFIIICSITILNLVIAILVDVVIQK 226 >3RVY-A nrPDB Length = 285 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 46/182 (25%), Positives = 84/182 (46%), Gaps = 18/182 (9%) Query: 131 LCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLL 190 + + +F ++ ++ Y+ + F K+ W L V+ +SLV + E LR+ R+L Sbjct: 69 IVITIFTIEIILRIYVHRISFF-KDPWSLFDFFVVAISLVPTSSGF-----EILRVLRVL 122 Query: 191 RPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRE 250 R F L+ M+K + + +P M SV L+ + +F + LF E Sbjct: 123 RLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFG----------E 172 Query: 251 RL-TYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYA-IFFIVFTVIGSLFLMNLLT 308 R +F L ES +L ++T + ++ + YA +FFI F + + ++NL+ Sbjct: 173 RFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVV 232 Query: 309 AI 310 AI Sbjct: 233 AI 234 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 39/225 (17%), Positives = 96/225 (42%), Gaps = 52/225 (23%) Query: 471 ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGW 530 + N + I + +E++L+++ + + P ++FD + + LV Sbjct: 65 LFNQIVITIFTIEIILRIYVHRI-SFFKDPWSLFDFFVVAISLV---------------- 107 Query: 531 RPEMVGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVY 590 P G +++ R+L +L +FR + +P M+ + S ++ ++ M + ++ + + Sbjct: 108 -PTSSG----FEILRVLRVLRLFRLVTAVPQMRK---IVSALISVIPGMLSVIALMTLFF 159 Query: 591 YVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLM 650 Y+FAI+ LF E+ W F + TL+ +M Sbjct: 160 YIFAIMATQLFG------------------------ERFPEW---FGTLGESFYTLFQVM 192 Query: 651 VVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILE 695 + +W + + P++ ++F+ + V + + +NL +A+ ++ Sbjct: 193 TLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAICVD 237 >3WKV-A nrPDB Length = 196 Score = 37.4 bits (85), Expect = 0.023, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 53/96 (55%), Gaps = 5/96 (5%) Query: 461 PAERDDFILGI--LNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEIS 518 P E+D + ++ +V+++L++ L++FA G + + + P V DGL+ VV VL++ Sbjct: 72 PDEQDYAVTAFHYMSFAILVFFMLDLGLRIFAYGPKNFFTNPWEVADGLIVVVSFVLDLV 131 Query: 519 TLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIVFR 554 L H ++ LL LW + R++N +I+ R Sbjct: 132 LLFK---SHHFEALGLLILLRLWRVARIINGIIISR 164 >5EK0-A nrPDB Length = 296 Score = 37.4 bits (85), Expect = 0.024, Method: Compositional matrix adjust. Identities = 39/225 (17%), Positives = 102/225 (45%), Gaps = 42/225 (18%) Query: 472 LNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLV-LEISTLAVYRLPHPGW 530 +N VFI+ + +E++L+++ + + P ++FD ++ ++ +V + ++ L P Sbjct: 65 INVVFIILFTIEIILRIYVHRI-SFFKDPWSLFDFVVVIISIVGMFLADLIETYFVSPT- 122 Query: 531 RPEMVGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVY 590 + R++ + + R LR++ ++ M + S ++ ++ M + ++ + + Sbjct: 123 ------------LFRVIRLARIGRILRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFF 170 Query: 591 YVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLM 650 Y+FAI+ LF E+ W F + TL+ +M Sbjct: 171 YIFAIMATQLFG------------------------ERFPEW---FGTLGESFYTLFQVM 203 Query: 651 VVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILE 695 + +W + + P++ ++F+ + V + + +NL +A+I++ Sbjct: 204 TLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVD 248 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 46/193 (23%), Positives = 89/193 (46%), Gaps = 20/193 (10%) Query: 128 VEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDW-------TVSLSLVC 180 + V+ +++F ++ ++ Y+ + F K+ W L VV+++S+V T +S Sbjct: 65 INVVFIILFTIEIILRIYVHRISFF-KDPWSLFDFVVVIISIVGMFLADLIETYFVSPTL 123 Query: 181 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG 240 +R+ R+ R L+ M+K + + +P M SV L+ + +F + LF Sbjct: 124 FRVIRLARIGRILRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFG- 182 Query: 241 GKQDDGQDRERL-TYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYA-IFFIVFTVI 298 ER +F L ES +L ++T + ++ + YA +FFI F + Sbjct: 183 ---------ERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFV 233 Query: 299 GSLFLMNLLTAII 311 + ++NL+ AII Sbjct: 234 VTFVMINLVVAII 246 >6N4I-A nrPDB Length = 288 Score = 37.0 bits (84), Expect = 0.028, Method: Compositional matrix adjust. Identities = 54/281 (19%), Positives = 120/281 (42%), Gaps = 54/281 (19%) Query: 415 PEYQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNC 474 P +L+ + ++ ++ LI L L F+ ++ + E + +L I N Sbjct: 14 PRGSHMYLRITNIVESSFFTKFIIYLIVLNTL-----FMAMEHHPMTEEFKN-VLAIGNL 67 Query: 475 VFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEM 534 VF + +E++L+++ + + P ++FD L I TL++ L + ++ Sbjct: 68 VFTGIFAIEIILRIYVHRI-SFFKDPWSLFDSL---------IVTLSLVEL----FLADV 113 Query: 535 VGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFA 594 GL L R +L VFR + +P M+ + S ++ ++ M + ++ + +Y+FA Sbjct: 114 EGLSVL----RSFRLLRVFRLVTAVPQMR---KIVSALISVIPGMLSVIALMTLFFYIFA 166 Query: 595 IIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNN 654 I+ LF E+ W F + TL+ +M + + Sbjct: 167 IMATQLFG------------------------ERFPEW---FGTLGESFYTLFQVMTLES 199 Query: 655 WQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILE 695 W + + P++ ++F+ + V + + +NL +A+ ++ Sbjct: 200 WSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAICVD 240 Score = 36.2 bits (82), Expect = 0.050, Method: Compositional matrix adjust. Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 14/178 (7%) Query: 135 VFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFF 194 +FA ++ ++ Y+ + F K+ W L +++ +SLV+ ++ + LR RLLR F Sbjct: 72 IFAIEIILRIYVHRISFF-KDPWSLFDSLIVTLSLVELFLA-DVEGLSVLRSFRLLRVFR 129 Query: 195 LLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERL-T 253 L+ M+K + + +P M SV L+ + +F + LF ER Sbjct: 130 LVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFG----------ERFPE 179 Query: 254 YFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYA-IFFIVFTVIGSLFLMNLLTAI 310 +F L ES +L ++T + ++ + YA +FFI F + + ++NL+ AI Sbjct: 180 WFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAI 237 >4G7Y-S nrPDB Length = 185 Score = 36.6 bits (83), Expect = 0.044, Method: Compositional matrix adjust. Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 16/113 (14%) Query: 472 LNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEI--STLAVYRLPHPG 529 L+C Y++L++ L++FA G + + + P V DGL+ VV V+ I + L Y Sbjct: 79 LSC----YFMLDLGLRIFAYGPKNFFTNPWEVADGLIIVVTFVVTIFYTVLDEY------ 128 Query: 530 WRPEMVGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAF 582 + G L ++ + +L V R RI S + M AS+ + QN R + Sbjct: 129 --VQETGADGLGELVVLARLLRVVRLARIFYSHQQMK--ASSRRTISQNKRRY 177 >4BGN-A nrPDB Length = 298 Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust. Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 36/142 (25%) Query: 558 IIPSMKLMAVVASTVLGLVQNMRAFGGILVV---VYYVFAIIGINLFRGVIVALPGNSSL 614 +IPS++ + V L+ + + G I+++ ++Y+F ++G LFR V Sbjct: 129 VIPSLRRL------VSALLYTIPSLGNIMLLMGLIFYIFGVMGTFLFRDV---------- 172 Query: 615 APANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYF 674 AP EY F +L+TL+ ++ + +W + WS IYF Sbjct: 173 AP-------------EY----FGSLHLSLITLFQVVTLESWASGIMRPIMAEVFWSWIYF 215 Query: 675 VLWWLVSSVIWVNLFLALILEN 696 V + LV + + NLF+ +I+ N Sbjct: 216 VAFILVGTFVIFNLFVGVIVSN 237 >4G80-S nrPDB Length = 155 Score = 32.7 bits (73), Expect = 0.62, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 4/46 (8%) Query: 472 LNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEI 517 L+C Y++L++ L++FA G + + + P V DGL+ VV V+ I Sbjct: 68 LSC----YFMLDLGLRIFAYGPKNFFTNPWEVADGLIIVVTFVVTI 109 >6E2G-A nrPDB Length = 727 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 9/69 (13%) Query: 247 QDRERLTYFQNLPESLTS----LLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLF 302 +D + L +F + P +L S L ++ N DV +P Y+I + F +I +L Sbjct: 514 EDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPF-----MYSITYAAFAIIATLL 568 Query: 303 LMNLLTAII 311 ++NLL A++ Sbjct: 569 MLNLLIAMM 577 >6BOA-A nrPDB Length = 742 Score = 30.0 bits (66), Expect = 3.5, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 9/69 (13%) Query: 247 QDRERLTYFQNLPESLTS----LLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLF 302 +D E L +F + P +L S L ++ N +V +P Y+I + F +I +L Sbjct: 515 EDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPFM-----YSITYAAFAIIATLL 569 Query: 303 LMNLLTAII 311 ++NLL A++ Sbjct: 570 MLNLLIAMM 578 >5T5I-A nrPDB Length = 569 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 5/57 (8%) Query: 649 LMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRS 705 L++ N +V L +GP+++ V+ WL+S+ +NL +E LHKW R Sbjct: 372 LLIDNPEKVCLTTDSPNAGPFTRYPRVIAWLMSNKYRMNL-----IEGELHKWAQRK 423 >4F4L-A nrPDB Length = 112 Score = 29.3 bits (64), Expect = 6.4, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 53/115 (46%), Gaps = 27/115 (23%) Query: 581 AFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFA 640 + +L VV+Y+ A++ NL+ +F + W F D + Sbjct: 8 SVAALLTVVFYIAAVMATNLYGA---------------------TFPE---W---FGDLS 40 Query: 641 AALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILE 695 +L TL+ +M + +W + + P + ++F+ + ++++ +NLF+ +I++ Sbjct: 41 KSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 95 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6NQ0-A nrPDB 1030 0.0 5E1J-A nrPDB 617 e-177 6C96-A nrPDB 515 e-146 5HVD-A nrPDB 189 3e-48 4DXW-A nrPDB 148 7e-36 6DU8-A nrPDB 123 4e-28 5Z1W-A nrPDB 115 1e-25 4LTR-A nrPDB 97 3e-20 5HKD-A nrPDB 94 2e-19 Sequences not found previously or not previously below threshold: 5EK0-A nrPDB 125 9e-29 3RVY-A nrPDB 122 7e-28 6N4I-A nrPDB 120 3e-27 4PA4-A nrPDB 98 2e-20 4BGN-A nrPDB 96 7e-20 4F4L-A nrPDB 93 4e-19 5MKE-A nrPDB 79 7e-15 6D1W-A nrPDB 74 2e-13 5T4D-A nrPDB 71 1e-12 4G7Y-S nrPDB 52 9e-07 4G80-S nrPDB 49 1e-05 6G1K-A nrPDB 42 8e-04 3WKV-A nrPDB 42 0.001 6CV9-A nrPDB 40 0.003 4JTA-B nrPDB 40 0.004 5Z96-A nrPDB 40 0.005 2A79-B nrPDB 38 0.014 6E2G-A nrPDB 38 0.018 6BOA-A nrPDB 35 0.099 6AYG-A nrPDB 35 0.15 6DMR-A nrPDB 34 0.19 5VA1-A nrPDB 34 0.27 6CUD-A nrPDB 32 0.86 5MRF-DD nrPDB 31 2.2 >6NQ0-A nrPDB Length = 756 Score = 1030 bits (2662), Expect = 0.0, Method: Composition-based stats. Identities = 748/752 (99%), Positives = 748/752 (99%) Query: 1 MAEPQAESEPLLGGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR 60 MAEPQAESEP GGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR Sbjct: 5 MAEPQAESEPAAGGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR 64 Query: 61 SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP 120 SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP Sbjct: 65 SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP 124 Query: 121 PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC 180 PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC Sbjct: 125 PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC 184 Query: 181 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG 240 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG Sbjct: 185 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG 244 Query: 241 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS 300 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS Sbjct: 245 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS 304 Query: 301 LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ 360 LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ Sbjct: 305 LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ 364 Query: 361 NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP 420 NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP Sbjct: 365 NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP 424 Query: 421 FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY 480 FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY Sbjct: 425 FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY 484 Query: 481 LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL 540 LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL Sbjct: 485 LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL 544 Query: 541 WDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL 600 WDMTRMLNMLIVFRFLRIIPSMK MAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL Sbjct: 545 WDMTRMLNMLIVFRFLRIIPSMKPMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL 604 Query: 601 FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD 660 FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD Sbjct: 605 FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD 664 Query: 661 AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM 720 AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM Sbjct: 665 AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM 724 Query: 721 TVELLFRDILEEPGEDELTERLSQHPHLWLCR 752 TVELLFRDILEEP EDELTERLSQHPHLWLCR Sbjct: 725 TVELLFRDILEEPEEDELTERLSQHPHLWLCR 756 >5E1J-A nrPDB Length = 741 Score = 617 bits (1590), Expect = e-177, Method: Composition-based stats. Identities = 186/748 (24%), Positives = 324/748 (43%), Gaps = 122/748 (16%) Query: 8 SEPLLGGARGGGGDWPAGLTTYRSIQVGPG-----AAARWDLCIDQAVVFIEDAIQYRSI 62 +PL+G GGG RS + G AAA DL D + +E Sbjct: 2 EDPLIGRDSLGGG---GTDRVRRSEAITHGTPFQKAAALVDLAEDGIGLPVE-------- 50 Query: 63 NHRVDASSMWLYRRYYSNVCQRTL--SFTIFLILFLAFIETP-----SSLTSTADVRYRA 115 +D SS RYY + L S F +LFL F E P + S D Y Sbjct: 51 --ILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYY 108 Query: 116 APWEPPCGLTESV--EVLCLLVFAAD----LSVKGYLFGWAHFQKNLWLLGYLVVLVVSL 169 P ES+ EV+ L + +S +G W + NL + +V+L V + Sbjct: 109 LGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTS-RLNLVKVACVVILFVDV 167 Query: 170 VDWTVSLSLVCHE--PLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHL 227 + + LS + + P RI +R + + ++ TL + L ++ L + L Sbjct: 168 LVDFLYLSPLAFDFLPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFL 227 Query: 228 CLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRA 287 + ++F +Q LT F + +L + +L TT+NNPDV IPAY +R Sbjct: 228 LFASWIAFVMFEDTQQG-------LTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRW 280 Query: 288 YAIFFIVFTVIGSLFLMNLLTAIIYSQFRGYLMKSLQ-TSLFRRRLGTRAAFEVLSSMVG 346 ++FF+++ +IG F+ NL+ A++Y F+ L K + +RR+ +A + S G Sbjct: 281 SSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNG 340 Query: 347 EGGAFPQAVGVKPQNLLQVLQKVQLDSSHKQAMMEKVRSYGS-VLLSAEEFQKLFNELDR 405 E +D + + E++ +Y + +S EEF +F+ELD Sbjct: 341 E-----------------------IDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDD 377 Query: 406 S--------------------VVKEHPPR-----PE-YQSPFLQSAQFLFGHYYFDYLGN 439 + KE P P+ Y S Q + F Y + Sbjct: 378 TRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAIS 437 Query: 440 LIALANLVSICVFLVLDADVLPAERDD----FILGILNCVFIVYYLLEMLLKVFALGLRG 495 I + N +++ V LD + A++ F+ G + Y+LEM LK++ G Sbjct: 438 FILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWI-------YVLEMALKIYTYGFEN 490 Query: 496 YLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIVFRF 555 Y +N FD L+T V+++ E +T P+ S + R L + + R Sbjct: 491 YWREGANRFDFLVTWVIVIGETATFIT---------PDENTFFSNGEWIRYLLLARMLRL 541 Query: 556 LRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLA 615 +R++ +++ +T + L+ ++ + G + V ++ IG+ +F G++ A GN L Sbjct: 542 IRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNA--GNKKLF 599 Query: 616 PANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGP-WSKIYF 674 + +Y NF+D+ +VTL+NL+V+ NWQV++++Y+ +G WS YF Sbjct: 600 ET-------ELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYF 652 Query: 675 VLWWLVSSVIWVNLFLALILENFLHKWD 702 V +++++ ++ +NL +A +LE F + D Sbjct: 653 VSFYVITILLLLNLVVAFVLEAFFTELD 680 >6C96-A nrPDB Length = 825 Score = 515 bits (1327), Expect = e-146, Method: Composition-based stats. Identities = 160/598 (26%), Positives = 271/598 (45%), Gaps = 66/598 (11%) Query: 127 SVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRI 186 ++E+ L+V +L +K G+ F ++ + VLVV ++ V L +R+ Sbjct: 143 TLELFALMVVVFELCMKLRWLGFHTFVRHKRTMVKTSVLVVQFIEAIVVLVRQTSH-VRV 201 Query: 187 RRLLRPFFLL--QNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQD 244 R LR FL+ + +++ L+ I SLP + LLL + +F + G LF+ D Sbjct: 202 TRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFSTNPSD 261 Query: 245 DGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLM 304 YF L S+ +L VLLTTAN PDVM+P+YS+N +FFIV+ I F+M Sbjct: 262 P--------YFSTLENSIVNLFVLLTTANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIM 313 Query: 305 NLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGG-AFPQAVGVKPQNLL 363 NLL A+++ F ++ L +R + A+ +L+S G ++ Q G L Sbjct: 314 NLLLAVVFDTFNDIEKHKFKSLLLHKRTAIQHAYGLLASQRRPAGISYRQFEG------L 367 Query: 364 QVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFN--------ELDRSVVKEHPPRP 415 K ++ + + + + + LLS ++F ++ + +R + PR Sbjct: 368 MRFYKPRMSARERFLTFKALNQSNTPLLSLKDFYDIYEVAALQWKAKRNRQHWFDELPRT 427 Query: 416 EYQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICV--FLVLDADVLPAERDDFILGILN 473 + + L F Y L+ N V I V F++ + L Sbjct: 428 AFL--IFKGINILVNSKAFQYFMYLVVAVNGVWILVETFMLKGGNFTSKHVPWSYL---- 481 Query: 474 CVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPE 533 VF+ Y +E+ +KV LG YLS N+FD +T Sbjct: 482 -VFLTIYGVELFMKVAGLGPVEYLSSGWNLFDFSVTAFA--------------------- 519 Query: 534 MVGLLSLWDMTRMLNMLIVFR---FLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVY 590 +GLL+L ++V R LR+ K V T+ L+ M + G L+ Y Sbjct: 520 FLGLLALTLNMEPFYFIVVLRPLQLLRLFKLKKRYRNVLDTMFELLPRMASLGLTLLTFY 579 Query: 591 YVFAIIGINLFRGVIVALPGN-SSLAPANG--SAPCGSFEQLE---YWANNFDDFAAALV 644 Y FAI+G+ F G + N S++A A + G+ ++E Y+ NNFD+ + V Sbjct: 580 YSFAIVGMEFFNGRLTPNCCNTSTVADAYRFINHTVGNKTKVEEGYYYLNNFDNILNSFV 639 Query: 645 TLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWD 702 TL+ L VVNNW + ++ + WS++YF+ +++V+ V+ + + +A ILE F+ + + Sbjct: 640 TLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVV-MTIIVAFILEAFVFRMN 696 >5HVD-A nrPDB Length = 277 Score = 189 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 46/193 (23%), Positives = 91/193 (47%), Gaps = 15/193 (7%) Query: 123 GLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHE 182 L E V+ LCL +F ++S+K Y +G F ++ W L V++ ++L+ SLS+ Sbjct: 46 NLLERVDQLCLTIFIVEISLKIYAYGVRGFFRSGWNLFDFVIVAIALMPAQGSLSV---- 101 Query: 183 PLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGK 242 LR R+ R L+ M++ ++ + +LP + SV LL + + + L+ Sbjct: 102 -LRTFRIFRVMRLVSVIPTMRRVVQGMLLALPGVGSVAALLTVVFYIAAVMATNLYGATF 160 Query: 243 QDDGQDRERLTYFQNLPESLTSLLVLLTTANN-PDVMIPAYSKNRAYAIFFIVFTVIGSL 301 + +F +L +SL +L ++T + ++ P + + +FFI F ++ + Sbjct: 161 PE---------WFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTF 211 Query: 302 FLMNLLTAIIYSQ 314 ++NL I Sbjct: 212 TVLNLFIGICVDA 224 Score = 165 bits (418), Expect = 6e-41, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 115/278 (41%), Gaps = 55/278 (19%) Query: 419 SPFLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIV 478 S + + L F + I + N + + D + +L ++ + + Sbjct: 2 SHMSRKIRDLIESKRFQNVITAIIVLNGAVLGLLT----DTTLSASSQNLLERVDQLCLT 57 Query: 479 YYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLL 538 +++E+ LK++A G+RG+ N+FD ++ + L+ +L+V Sbjct: 58 IFIVEISLKIYAYGVRGFFRSGWNLFDFVIVAIALMPAQGSLSVL--------------- 102 Query: 539 SLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGI 598 R + V R + +IP+M+ VV +L L + + +L VV+Y+ A++ Sbjct: 103 ------RTFRIFRVMRLVSVIPTMR--RVVQGMLLAL-PGVGSVAALLTVVFYIAAVMAT 153 Query: 599 NLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVF 658 NL+ +F + F D + +L TL+ +M + +W + Sbjct: 154 NLYG---------------------ATFPEW------FGDLSKSLYTLFQVMTLESWSMG 186 Query: 659 LDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 + P + ++F+ + ++++ +NLF+ + ++ Sbjct: 187 IVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGICVDA 224 >4DXW-A nrPDB Length = 229 Score = 148 bits (374), Expect = 7e-36, Method: Composition-based stats. Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%) Query: 150 AHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCI 209 A F K+ W + V++ +SL+ + S + LRI R+LR L+ +K+ ++ I Sbjct: 70 ADFFKSGWNIFDTVIVAISLIPIPNNSSFLVLRLLRIFRVLR---LISVIPELKQIIEAI 126 Query: 210 RWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLL 269 S+ + V LLL I L ++ G +LF G D + + +L SL +L +L Sbjct: 127 LESVRRVFFVSLLLFIILYIYATMGAILF--GNDDPSR-------WGDLGISLITLFQVL 177 Query: 270 TTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYS 313 T ++ VM+P ++F F +I S+ ++NL+ AI+ Sbjct: 178 TLSSWETVMLPMQEIYWWSWVYFFSFIIICSITILNLVIAILVD 221 Score = 78.6 bits (192), Expect = 9e-15, Method: Composition-based stats. Identities = 36/224 (16%), Positives = 94/224 (41%), Gaps = 51/224 (22%) Query: 478 VYYLLEMLLKVFALGLR-GYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVG 536 +++++E+L++ + + N+FD ++ + L+ + Sbjct: 53 IFFVIEILIRFIGEKQKADFFKSGWNIFDTVIVAISLIPIPNN----------------- 95 Query: 537 LLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAII 596 S + + R+L + V R + +IP +K + +L V+ + +L ++ Y++A + Sbjct: 96 --SSFLVLRLLRIFRVLRLISVIPELK---QIIEAILESVRRVFFVSLLLFIILYIYATM 150 Query: 597 GINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQ 656 G LF + + D +L+TL+ ++ +++W+ Sbjct: 151 GAILFGNDDPS---------------------------RWGDLGISLITLFQVLTLSSWE 183 Query: 657 VFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHK 700 + + WS +YF + ++ S+ +NL +A++++ + K Sbjct: 184 TVML-PMQEIYWWSWVYFFSFIIICSITILNLVIAILVDVVIQK 226 >5EK0-A nrPDB Length = 296 Score = 125 bits (313), Expect = 9e-29, Method: Composition-based stats. Identities = 41/269 (15%), Positives = 112/269 (41%), Gaps = 45/269 (16%) Query: 428 LFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYYLLEMLLK 487 + +F + + N+V++ V ++ +L +N VFI+ + +E++L+ Sbjct: 26 IVESSFFTKFIIYLIVLNMVTMMVE-----KEGQSQHMTEVLYWINVVFIILFTIEIILR 80 Query: 488 VFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRML 547 ++ + + P ++FD ++ ++ +V + + R++ Sbjct: 81 IYVHRI-SFFKDPWSLFDFVVVIISIVGMFLADLI------------ETYFVSPTLFRVI 127 Query: 548 NMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVA 607 + + R LR++ ++ M + S ++ ++ M + ++ + +Y+FAI+ LF Sbjct: 128 RLARIGRILRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGER--- 184 Query: 608 LPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSG 667 F + F + TL+ +M + +W + + Sbjct: 185 ------------------FPEW------FGTLGESFYTLFQVMTLESWSMGIVRPLMEVY 220 Query: 668 PWSKIYFVLWWLVSSVIWVNLFLALILEN 696 P++ ++F+ + V + + +NL +A+I++ Sbjct: 221 PYAWVFFIPFIFVVTFVMINLVVAIIVDA 249 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 86/195 (44%), Gaps = 18/195 (9%) Query: 128 VEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVS-------LSLVC 180 + V+ +++F ++ ++ Y+ F K+ W L VV+++S+V ++ +S Sbjct: 65 INVVFIILFTIEIILRIYVHRI-SFFKDPWSLFDFVVVIISIVGMFLADLIETYFVSPTL 123 Query: 181 HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG 240 +R+ R+ R L+ M+K + + +P M SV L+ + +F + LF Sbjct: 124 FRVIRLARIGRILRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGE 183 Query: 241 GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANN-PDVMIPAYSKNRAYAIFFIVFTVIG 299 + +F L ES +L ++T + ++ P +FFI F + Sbjct: 184 RFPE---------WFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVV 234 Query: 300 SLFLMNLLTAIIYSQ 314 + ++NL+ AII Sbjct: 235 TFVMINLVVAIIVDA 249 >6DU8-A nrPDB Length = 805 Score = 123 bits (308), Expect = 4e-28, Method: Composition-based stats. Identities = 42/158 (26%), Positives = 76/158 (48%), Gaps = 20/158 (12%) Query: 465 DDFILG--ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLV-------- 514 D FI+G ++ CVFI YY++E +L++ LR YLS N+ D ++ ++ +V Sbjct: 349 DFFIVGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFR 407 Query: 515 -LEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLMAV 567 LE++ L L P + L+ W T+ NM V + + I K M Sbjct: 408 TLEVNRLMGKLLQQPNTYADFE-FLAFW-QTQYNNMNAVNLFFAWIKIFKYISFNKTMTQ 465 Query: 568 VASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVI 605 ++ST+ +++ F + +V++ +A +G LF + Sbjct: 466 LSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQV 503 >3RVY-A nrPDB Length = 285 Score = 122 bits (305), Expect = 7e-28, Method: Composition-based stats. Identities = 43/187 (22%), Positives = 80/187 (42%), Gaps = 16/187 (8%) Query: 129 EVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRR 188 + + +F ++ ++ Y+ F K+ W L V+ +SLV + E LR+ R Sbjct: 67 NQIVITIFTIEIILRIYVHRI-SFFKDPWSLFDFFVVAISLVP-----TSSGFEILRVLR 120 Query: 189 LLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQD 248 +LR F L+ M+K + + +P M SV L+ + +F + LF + Sbjct: 121 VLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPE---- 176 Query: 249 RERLTYFQNLPESLTSLLVLLTTANN-PDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLL 307 +F L ES +L ++T + ++ P +FFI F + + ++NL+ Sbjct: 177 -----WFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLV 231 Query: 308 TAIIYSQ 314 AI Sbjct: 232 VAICVDA 238 Score = 120 bits (301), Expect = 2e-27, Method: Composition-based stats. Identities = 38/269 (14%), Positives = 101/269 (37%), Gaps = 56/269 (20%) Query: 428 LFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYYLLEMLLK 487 + +F + + N +++ + + + N + I + +E++L+ Sbjct: 26 IVESSFFTKFIIYLIVLNGITMGLETSK----TFMQSFGVYTTLFNQIVITIFTIEIILR 81 Query: 488 VFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMTRML 547 ++ + + P ++FD + + LV S +L Sbjct: 82 IYVHRI-SFFKDPWSLFDFFVVAISLVPTSSGF------------------------EIL 116 Query: 548 NMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVA 607 +L V R R++ ++ M + S ++ ++ M + ++ + +Y+FAI+ LF Sbjct: 117 RVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGER--- 173 Query: 608 LPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSG 667 F + F + TL+ +M + +W + + Sbjct: 174 ------------------FPEW------FGTLGESFYTLFQVMTLESWSMGIVRPLMEVY 209 Query: 668 PWSKIYFVLWWLVSSVIWVNLFLALILEN 696 P++ ++F+ + V + + +NL +A+ ++ Sbjct: 210 PYAWVFFIPFIFVVTFVMINLVVAICVDA 238 >6N4I-A nrPDB Length = 288 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 43/181 (23%), Positives = 81/181 (44%), Gaps = 12/181 (6%) Query: 135 VFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFF 194 +FA ++ ++ Y+ F K+ W L +++ +SLV+ ++ + LR RLLR F Sbjct: 72 IFAIEIILRIYVHRI-SFFKDPWSLFDSLIVTLSLVELFLA-DVEGLSVLRSFRLLRVFR 129 Query: 195 LLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTY 254 L+ M+K + + +P M SV L+ + +F + LF + + Sbjct: 130 LVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPE---------W 180 Query: 255 FQNLPESLTSLLVLLTTANN-PDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYS 313 F L ES +L ++T + ++ P +FFI F + + ++NL+ AI Sbjct: 181 FGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAICVD 240 Query: 314 Q 314 Sbjct: 241 A 241 Score = 115 bits (287), Expect = 8e-26, Method: Composition-based stats. Identities = 38/229 (16%), Positives = 93/229 (40%), Gaps = 48/229 (20%) Query: 468 ILGILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPH 527 +L I N VF + +E++L+++ + + P ++FD L+ + LV Sbjct: 61 VLAIGNLVFTGIFAIEIILRIYVHRI-SFFKDPWSLFDSLIVTLSLV------------- 106 Query: 528 PGWRPEMVGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILV 587 L+ + +L + R R++ ++ M + S ++ ++ M + ++ Sbjct: 107 -------ELFLADVEGLSVLRSFRLLRVFRLVTAVPQMRKIVSALISVIPGMLSVIALMT 159 Query: 588 VVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLW 647 + +Y+FAI+ LF F + F + TL+ Sbjct: 160 LFFYIFAIMATQLFGER---------------------FPEW------FGTLGESFYTLF 192 Query: 648 NLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 +M + +W + + P++ ++F+ + V + + +NL +A+ ++ Sbjct: 193 QVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAICVDA 241 >5Z1W-A nrPDB Length = 566 Score = 115 bits (287), Expect = 1e-25, Method: Composition-based stats. Identities = 42/158 (26%), Positives = 76/158 (48%), Gaps = 20/158 (12%) Query: 465 DDFILG--ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLV-------- 514 D FI+G ++ CVFI YY++E +L++ LR YLS N+ D ++ ++ +V Sbjct: 286 DFFIVGCEVVFCVFIFYYVVEEILEIHLHRLR-YLSSVWNILDLVVILLSIVAVGFHIFR 344 Query: 515 -LEISTLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLMAV 567 LE++ L L P + L+ W T+ NM V + + I K M Sbjct: 345 TLEVNRLMGKLLQQPDTYADFE-FLAFW-QTQYNNMNAVNLFFAWIKIFKYISFNKTMTQ 402 Query: 568 VASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVI 605 ++ST+ +++ F + +V++ +A +G LF + Sbjct: 403 LSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQV 440 >4PA4-A nrPDB Length = 149 Score = 97.5 bits (241), Expect = 2e-20, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Query: 215 EMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTTANN 274 + SV LL + + + L+ + +F +L +SL +L ++T + Sbjct: 5 GVGSVAALLTVVFYIAAVMATNLYGATFPE---------WFGDLSKSLYTLFQVMTLESW 55 Query: 275 -PDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQ 314 ++ P + + +FFI F ++ + ++NL II Sbjct: 56 SMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDA 96 Score = 93.7 bits (231), Expect = 3e-19, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 53/119 (44%), Gaps = 27/119 (22%) Query: 578 NMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFD 637 + + +L VV+Y+ A++ NL+ +F + F Sbjct: 5 GVGSVAALLTVVFYIAAVMATNLYG---------------------ATFPEW------FG 37 Query: 638 DFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 D + +L TL+ +M + +W + + P + ++F+ + ++++ +NLF+ +I++ Sbjct: 38 DLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDA 96 >4LTR-A nrPDB Length = 152 Score = 97.1 bits (240), Expect = 3e-20, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 27/126 (21%) Query: 571 TVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLE 630 ++L + + +L+V++YVFA++G LF SF + Sbjct: 6 SLLRAIPGIAWIALLLLVIFYVFAVMGTKLF---------------------AQSFPEW- 43 Query: 631 YWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFL 690 F A++ TL+ +M + +W + + + PW+ IYFV + LVSS +NLF+ Sbjct: 44 -----FGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFI 98 Query: 691 ALILEN 696 +I+E+ Sbjct: 99 GIIIES 104 Score = 89.0 bits (219), Expect = 7e-18, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 209 IRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVL 268 + ++P +A + LLL + +F + G LFA + +F L S+ +L + Sbjct: 7 LLRAIPGIAWIALLLLVIFYVFAVMGTKLFAQSFPE---------WFGTLGASMYTLFQV 57 Query: 269 LTTANN-PDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQFR 316 +T + + P I+F+ F ++ S ++NL II + Sbjct: 58 MTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQ 106 >4BGN-A nrPDB Length = 298 Score = 95.6 bits (236), Expect = 7e-20, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 88/199 (44%), Gaps = 15/199 (7%) Query: 118 WEPPCGLTESVEVLCLLVFAADLSVKGYLFGWA-HFQKNLWLLGYLVVLVVSLVDWTVSL 176 ++P ++ + L VF A++ +K HF K+ W + +++ + + Sbjct: 52 YQPYQDWFYLIDRMILWVFTAEIILKLVATRPRYHFFKDSWNVFDFLIVA----SGHLFV 107 Query: 177 SLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGML 236 LR+ R+LR + +++ + + +++P + ++ LL+ + +F + G Sbjct: 108 GAQFVTVLRVLRVLRLLRAVTVIPSLRRLVSALLYTIPSLGNIMLLMGLIFYIFGVMGTF 167 Query: 237 LFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTTANN-PDVMIPAYSKNRAYAIFFIVF 295 LF + YF +L SL +L ++T + +M P ++ I+F+ F Sbjct: 168 LFRDVAPE---------YFGSLHLSLITLFQVVTLESWASGIMRPIMAEVFWSWIYFVAF 218 Query: 296 TVIGSLFLMNLLTAIIYSQ 314 ++G+ + NL +I S Sbjct: 219 ILVGTFVIFNLFVGVIVSN 237 Score = 89.8 bits (221), Expect = 4e-18, Method: Composition-based stats. Identities = 51/287 (17%), Positives = 105/287 (36%), Gaps = 55/287 (19%) Query: 411 HPPRPEYQSPFLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILG 470 H + + P +L H F ++ + N + + + +D F L Sbjct: 5 HERHSQLKHPIEAWCDWLVNHPRFTSAIIVLIVINAIVVGMETYPGI--YQPYQDWFYL- 61 Query: 471 ILNCVFIVYYLLEMLLKVFALGLR-GYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPG 529 ++ + + + E++LK+ A R + NVFD L+ + + Sbjct: 62 -IDRMILWVFTAEIILKLVATRPRYHFFKDSWNVFDFLIVASGHLFVGAQFVTVLRVLRV 120 Query: 530 WRPEMVGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVV 589 R + +IPS++ + S +L + ++ ++ ++ Sbjct: 121 LRLLRA--------------------VTVIPSLRR---LVSALLYTIPSLGNIMLLMGLI 157 Query: 590 YYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNL 649 +Y+F ++G LFR +AP F +L+TL+ + Sbjct: 158 FYIFGVMGTFLFR----------DVAPEY-----------------FGSLHLSLITLFQV 190 Query: 650 MVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 + + +W + WS IYFV + LV + + NLF+ +I+ N Sbjct: 191 VTLESWASGIMRPIMAEVFWSWIYFVAFILVGTFVIFNLFVGVIVSN 237 >5HKD-A nrPDB Length = 152 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 27/126 (21%) Query: 571 TVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLE 630 ++L + + +L+V++YVFA++G LF SF + Sbjct: 6 SLLRAIPGIAWIALLLLVIFYVFAVMGTKLF---------------------AQSFPEW- 43 Query: 631 YWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFL 690 F A++ TL+ +M + +W + + + PW+ IYFV + LVSS +NLF+ Sbjct: 44 -----FGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFI 98 Query: 691 ALILEN 696 +I+E+ Sbjct: 99 GIIIES 104 Score = 86.3 bits (212), Expect = 4e-17, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 209 IRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVL 268 + ++P +A + LLL + +F + G LFA + +F L S+ +L + Sbjct: 7 LLRAIPGIAWIALLLLVIFYVFAVMGTKLFAQSFPE---------WFGTLGASMYTLFQV 57 Query: 269 LTTANN-PDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQFR 316 +T + + P I+F+ F ++ S ++NL II + Sbjct: 58 MTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQ 106 >4F4L-A nrPDB Length = 112 Score = 93.3 bits (230), Expect = 4e-19, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Query: 215 EMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTTANN 274 + SV LL + + + L+ + +F +L +SL +L ++T + Sbjct: 5 GVGSVAALLTVVFYIAAVMATNLYGATFPE---------WFGDLSKSLYTLFQVMTLESW 55 Query: 275 -PDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQ 314 ++ P + + +FFI F ++ + ++NL II Sbjct: 56 SMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDA 96 Score = 89.0 bits (219), Expect = 7e-18, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 53/119 (44%), Gaps = 27/119 (22%) Query: 578 NMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFD 637 + + +L VV+Y+ A++ NL+ +F + F Sbjct: 5 GVGSVAALLTVVFYIAAVMATNLYG---------------------ATFPEW------FG 37 Query: 638 DFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 D + +L TL+ +M + +W + + P + ++F+ + ++++ +NLF+ +I++ Sbjct: 38 DLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDA 96 >5MKE-A nrPDB Length = 968 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 88/241 (36%), Gaps = 48/241 (19%) Query: 471 ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDG--------LLTVVLLVLEISTLAV 522 I+ C FI YY++E +L++ L Y N D + + + + + Sbjct: 478 IIFCFFIFYYVVEEILEIRIHKL-HYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLL 536 Query: 523 YRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLMAVVASTVLGLV 576 L P L+ W + N+ V + + I + M+ +++T+ Sbjct: 537 QFLEDQNTFPNFEH-LAYW-QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCA 594 Query: 577 QNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNF 636 +++ F + +++ +A + +F + ++F Sbjct: 595 KDLFGFAIMFFIIFLAYAQLAYLVFGTQV----------------------------DDF 626 Query: 637 DDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 F + T + +++ + ++ R GP IYF + I +N+FLA+I + Sbjct: 627 STFQECIFTQFRIILGDINFAEIEEANRVLGP---IYFTTFVFFMFFILLNMFLAIINDT 683 Query: 697 F 697 + Sbjct: 684 Y 684 Score = 32.4 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 23/163 (14%), Positives = 50/163 (30%), Gaps = 24/163 (14%) Query: 187 RRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDG 246 ++ F + + M + + ++ ++ I + L+F D Sbjct: 568 FVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDD-- 625 Query: 247 QDRERLTYFQNLPESLTSLL-VLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMN 305 F E + + ++L N ++ I+F F L+N Sbjct: 626 --------FSTFQECIFTQFRIILGDINFAEIEEANRVLGP---IYFTTFVFFMFFILLN 674 Query: 306 LLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEG 348 + AII + + L + A LS ++ +G Sbjct: 675 MFLAIINDTYSEV----------KSDLAQQKAEMELSDLIRKG 707 >6D1W-A nrPDB Length = 740 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 88/241 (36%), Gaps = 48/241 (19%) Query: 471 ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDG--------LLTVVLLVLEISTLAV 522 I+ C FI YY++E +L++ L Y N D + + + + + Sbjct: 426 IIFCFFIFYYVVEEILEIRIHKL-HYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLL 484 Query: 523 YRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLMAVVASTVLGLV 576 L P L+ W + N+ V + + I + M+ +++T+ Sbjct: 485 QFLEDQNTFPNFEH-LAYW-QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCA 542 Query: 577 QNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNF 636 +++ F + +++ +A + +F + ++F Sbjct: 543 KDLFGFAIMPFIIFLAYAQLAYLVFGTQV----------------------------DDF 574 Query: 637 DDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 F + T + +++ + ++ R GP IYF + I +N+FLA+I + Sbjct: 575 STFQECIFTQFRIILGDINFAEIEEANRVLGP---IYFTTFVFFMFFILLNMFLAIINDT 631 Query: 697 F 697 + Sbjct: 632 Y 632 Score = 29.7 bits (65), Expect = 4.3, Method: Composition-based stats. Identities = 18/133 (13%), Positives = 40/133 (30%), Gaps = 14/133 (10%) Query: 187 RRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDG 246 ++ F + + M + + ++ ++ I + L+F D Sbjct: 516 FVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMPFIIFLAYAQLAYLVFGTQVDD-- 573 Query: 247 QDRERLTYFQNLPESLTSLL-VLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMN 305 F E + + ++L N ++ I+F F L+N Sbjct: 574 --------FSTFQECIFTQFRIILGDINFAEIEEANRVLGP---IYFTTFVFFMFFILLN 622 Query: 306 LLTAIIYSQFRGY 318 + AII + Sbjct: 623 MFLAIINDTYSEV 635 >5T4D-A nrPDB Length = 510 Score = 71.3 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 89/241 (36%), Gaps = 48/241 (19%) Query: 471 ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGL--------LTVVLLVLEISTLAV 522 I+ C FI YY++E +L++ L Y N D + + + + + + Sbjct: 286 IIFCFFIFYYVVEEILEIRIHKL-HYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLL 344 Query: 523 YRLPHPGWRPEMVGLLSLWDMTRMLNMLIV------FRFLRIIPSMKLMAVVASTVLGLV 576 L P L+ W + N+ V + + I + M+ +++T+ Sbjct: 345 QFLEDQNTFPNFEH-LAYW-QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCA 402 Query: 577 QNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNF 636 +++ F + +++ +A + +F + ++F Sbjct: 403 KDLFGFAIMFFIIFLAYAQLAYLVFGTQV----------------------------DDF 434 Query: 637 DDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 F + T + +++ + ++ R GP IYF + I +N+FLA+I + Sbjct: 435 STFQECIFTQFRIILGDINFAEIEEANRVLGP---IYFTTFVFFMFFILLNMFLAIINDT 491 Query: 697 F 697 + Sbjct: 492 Y 492 Score = 30.1 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 18/133 (13%), Positives = 40/133 (30%), Gaps = 14/133 (10%) Query: 187 RRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDG 246 ++ F + + M + + ++ ++ I + L+F D Sbjct: 376 FVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDD-- 433 Query: 247 QDRERLTYFQNLPESLTSLL-VLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMN 305 F E + + ++L N ++ I+F F L+N Sbjct: 434 --------FSTFQECIFTQFRIILGDINFAEIEEANRVLGP---IYFTTFVFFMFFILLN 482 Query: 306 LLTAIIYSQFRGY 318 + AII + Sbjct: 483 MFLAIINDTYSEV 495 >4G7Y-S nrPDB Length = 185 Score = 52.1 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 54/143 (37%), Gaps = 9/143 (6%) Query: 425 AQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYYLLEM 484 + + H G + +++ + + L L ++ + Y++L++ Sbjct: 31 VRAVIDHLGMRVFGVFLIFLDIILMIIDLSLPGKSESSQ---SFYDGMALALSCYFMLDL 87 Query: 485 LLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMT 544 L++FA G + + + P V DGL+ VV V + G L ++ Sbjct: 88 GLRIFAYGPKNFFTNPWEVADGLIIVVTFV------VTIFYTVLDEYVQETGADGLGELV 141 Query: 545 RMLNMLIVFRFLRIIPSMKLMAV 567 + +L V R RI S + M Sbjct: 142 VLARLLRVVRLARIFYSHQQMKA 164 >4G80-S nrPDB Length = 155 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 53/143 (37%), Gaps = 9/143 (6%) Query: 425 AQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYYLLEM 484 + + H G + +++ + + L L ++ + Y++L++ Sbjct: 20 VRAVIDHLGMRVFGVFLIFLDIILMIIDLSLPGKSESSQ---SFYDGMALALSCYFMLDL 76 Query: 485 LLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSLWDMT 544 L++FA G + + + P V DGL+ VV V + G L + Sbjct: 77 GLRIFAYGPKNFFTNPWEVADGLIIVVTFV------VTIFYTVLDEYVQETGADGLGRLV 130 Query: 545 RMLNMLIVFRFLRIIPSMKLMAV 567 + +L V R RI S + M Sbjct: 131 VLARLLRVVRLARIFYSHQQMKA 153 >6G1K-A nrPDB Length = 921 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 28/246 (11%), Positives = 87/246 (35%), Gaps = 19/246 (7%) Query: 461 PAERDDFILGILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTL 520 P + IL + ++ + +++ G + Y+ N+ D ++ + L + Sbjct: 399 PTTVEWMILPWVLG-----FIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKI 453 Query: 521 AVYRLPHPGWRPEMVGLLSLWDMTRML----NMLIVFRFLRIIPSMKLMAVVASTVLGLV 576 Y + + + + N+ R + + + + + ++ ++ Sbjct: 454 VAYVKYSGCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRML 513 Query: 577 QNMRAFGGILVVVYYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNF 636 ++ F I +V FA L+ + Q ++ F Sbjct: 514 LDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCER--------QNNAFSTLF 565 Query: 637 DDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILEN 696 + + +++ L+ + + + A +++ F + ++S V+ +N+ +A++ + Sbjct: 566 ETLQSLFWSIFGLISL--YVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNS 623 Query: 697 FLHKWD 702 + H D Sbjct: 624 YQHIAD 629 >3WKV-A nrPDB Length = 196 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 54/100 (54%), Gaps = 5/100 (5%) Query: 461 PAERDDFILGILNCVF--IVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEIS 518 P E+D + F +V+++L++ L++FA G + + + P V DGL+ VV VL+ Sbjct: 72 PDEQDYAVTAFHYMSFAILVFFMLDLGLRIFAYGPKNFFTNPWEVADGLIVVVSFVLD-- 129 Query: 519 TLAVYRLPHPGWRPEMVGLLSLWDMTRMLNMLIVFRFLRI 558 L + H ++ LL LW + R++N +I+ R ++ Sbjct: 130 -LVLLFKSHHFEALGLLILLRLWRVARIINGIIISRMKQL 168 >6CV9-A nrPDB Length = 842 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 27/205 (13%), Positives = 72/205 (35%), Gaps = 39/205 (19%) Query: 487 KVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVY-------RLPHPGWRPEMVGLLS 539 +++ G + YL N+ D + + I+ + + + + ++ Sbjct: 423 EIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVT 482 Query: 540 LWDMTRMLNMLIV-----------------------FRFLRIIPSMKLMAVVASTVLGLV 576 L D + N+ + R I+P+ + + ++ V Sbjct: 483 LGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV 542 Query: 577 QNMRAFGGILVVVYYVFAIIGINLFRGVIVA--LPGNSSLAPANGSAPCGSF--EQLEYW 632 +++ F I ++V+ F I NL+ I A +++ + + F +++ Sbjct: 543 KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSV 602 Query: 633 ANNFD-----DFAAALVTLWNLMVV 652 N++ + L ++N+ +V Sbjct: 603 VINYNHKFIENIGYVLYGVYNVTMV 627 Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 42/109 (38%), Gaps = 5/109 (4%) Query: 214 PEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLL-VLLTTA 272 + + + I + +F F + +F ++ F + ES +L + + Sbjct: 540 RTVKDIFKFMVIFIMVFVAFMIGMF--NLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLS 597 Query: 273 NNPDVMIPAYSKN--RAYAIFFIVFTVIGSLFLMNLLTAIIYSQFRGYL 319 V+I K + + V+ V + L+N+L A+I S F+ Sbjct: 598 EVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIE 646 >4JTA-B nrPDB Length = 514 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 59/147 (40%), Gaps = 11/147 (7%) Query: 128 VEVLCLLVFAADLSVKGYLF-GWAHFQKNLWLLGYLVVLVVSLVDWTVSLS--------- 177 VE LC++ F+ + V+ + A F N+ + +V ++ V ++ S Sbjct: 244 VETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYYVTIFLTESNKSVLQFQN 303 Query: 178 -LVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGML 236 + RI R+LR F L ++S ++ + ++ S+ E+ + L I + LF+ Sbjct: 304 VRRVVQIFRIMRILRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF 363 Query: 237 LFAGGKQDDGQDRERLTYFQNLPESLT 263 A + ++ + + Sbjct: 364 AEADERDSQFPSIPDAFWWAVVSMTTV 390 >5Z96-A nrPDB Length = 755 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 38/240 (15%), Positives = 93/240 (38%), Gaps = 20/240 (8%) Query: 465 DDFILGILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLL---VLEISTLA 521 I+ + +++ ++ + +++ GL+ Y+ N+ D ++ + L L+I Sbjct: 398 PPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV 457 Query: 522 VYRLPHPGWRPEM-VGLLSLWDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMR 580 Y +P +M L + + N+ R + + + + + ++ ++ ++ Sbjct: 458 KYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDIL 517 Query: 581 AFGGILVVVYYVFAIIGIN---LFRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFD 637 F I +V FA G+N + L +A FE L+ Sbjct: 518 KFLFIYCLVLLAFAN-GLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETLQSLFW--- 573 Query: 638 DFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENF 697 ++ L NL V N + A ++ F + ++S V+ +N+ +A++ ++ Sbjct: 574 ----SIFGLINLYVTN-----VKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSY 624 >2A79-B nrPDB Length = 499 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 59/151 (39%), Gaps = 15/151 (9%) Query: 128 VEVLCLLVFAADLSVKGYLF-GWAHFQKNLWLLGYLVVLVVSLV--------------DW 172 VE LC++ F+ + V+ + A F N+ + +V ++ + Sbjct: 225 VETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQG 284 Query: 173 TVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTM 232 ++SL +R+ R+ R F L ++S ++ + ++ S+ E+ + L I + LF+ Sbjct: 285 QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSS 344 Query: 233 FGMLLFAGGKQDDGQDRERLTYFQNLPESLT 263 A + ++ + + Sbjct: 345 AVYFAEADERDSQFPSIPDAFWWAVVSMTTV 375 >6E2G-A nrPDB Length = 727 Score = 37.8 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 30/198 (15%), Positives = 73/198 (36%), Gaps = 27/198 (13%) Query: 132 CLLVFAADLSVKGYLFGWAHFQKNLWL--LGYLVVLVVSLVDWTVSLSLVCHEPLRIRRL 189 +++ ++ + G F L +++++ + + + + + + + Sbjct: 395 AVIILLVEIP-DIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPM 453 Query: 190 --------LRPFFLLQNSSMMKKTLKCIRWSL-PEMASVGLLLAIHLCLFTMFGMLLFAG 240 + + M+ I+ + ++ L+A+ + F ++F Sbjct: 454 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQT 513 Query: 241 GKQDDGQDRERLTYFQNLPESLTSLLVLLTT----ANNPDVMIPAYSKNRAYAIFFIVFT 296 D+ L +F + P +L S L T N DV +P Y+I + F Sbjct: 514 EDPDE------LGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFM-----YSITYAAFA 562 Query: 297 VIGSLFLMNLLTAIIYSQ 314 +I +L ++NLL A++ Sbjct: 563 IIATLLMLNLLIAMMGDT 580 >6BOA-A nrPDB Length = 742 Score = 35.5 bits (80), Expect = 0.099, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 64/158 (40%), Gaps = 18/158 (11%) Query: 162 LVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSL-PEMASVG 220 LV +V+ L+ + + + + + + M+ I+ + ++ Sbjct: 437 LVTMVMRLISASGEVVPMSFAL--VLGWCNVMYFAEGFQMLGPFTIMIQKMIFGDLMRFC 494 Query: 221 LLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLTT----ANNPD 276 L+A+ + F ++F +D E L +F + P +L S L T N + Sbjct: 495 WLMAVVILGFASAFYIIFQT------EDPEELGHFYDYPMALFSTFELFLTIIDGPANYN 548 Query: 277 VMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQ 314 V +P Y+I + F +I +L ++NLL A++ Sbjct: 549 VDLPFM-----YSITYAAFAIIATLLMLNLLIAMMGDT 581 >6AYG-A nrPDB Length = 558 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 57/149 (38%), Gaps = 25/149 (16%) Query: 549 MLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINLFRGVIVAL 608 ML+ +R + ++ T+ + N+ F ++Y + F G IV Sbjct: 387 MLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYC------FCGWIVLG 440 Query: 609 PGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGP 668 P + N + C + N DD + + M ++ V+L Sbjct: 441 PYHDKFRSLNMVSEC------LFSLINGDD----MFATFAKMQQKSYLVWL--------- 481 Query: 669 WSKIYFVLWWLVSSVIWVNLFLALILENF 697 +S+IY + + + ++LF+ALI + + Sbjct: 482 FSRIYLYSFISLFIYMILSLFIALITDTY 510 >6DMR-A nrPDB Length = 730 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 40/108 (37%), Gaps = 12/108 (11%) Query: 212 SLPEMASVGLLLAIHLCLFTMFGML-LFAGGKQDDGQDRERLTYFQNLPESLTSLLVLLT 270 + +M L+ L + G F Q +D L F + P +L S L Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQ--TEDPNNLGEFSDYPTALFSTFELFL 538 Query: 271 T----ANNPDVMIPAYSKNRAYAIFFIVFTVIGSLFLMNLLTAIIYSQ 314 T N V +P Y I + F +I +L ++NL A++ Sbjct: 539 TIIDGPANYSVDLPFM-----YCITYAAFAIIATLLMLNLFIAMMGDT 581 Score = 30.9 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 32/70 (45%), Gaps = 8/70 (11%) Query: 627 EQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLDAYRRYSGPWSKIY---FVLWWLVSSV 683 + F D+ AL + + L + +D YS +Y + + +++++ Sbjct: 514 TEDPNNLGEFSDYPTALFSTFELFL-----TIIDGPANYSVDLPFMYCITYAAFAIIATL 568 Query: 684 IWVNLFLALI 693 + +NLF+A++ Sbjct: 569 LMLNLFIAMM 578 >5VA1-A nrPDB Length = 795 Score = 34.0 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 43/112 (38%), Gaps = 10/112 (8%) Query: 151 HFQKNLWLLGYLVVLVVSLVDWTVSLSLVCHEPLRIRRLLRPFFLLQNSSMMKKTLKCIR 210 H+ K W L +V + + S S L+ RLLR L++ + + + Sbjct: 252 HYFK-GWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLR---LVRVARKLDR------ 301 Query: 211 WSLPEMASVGLLLAIHLCLFTMFGMLLFAGGKQDDGQDRERLTYFQNLPESL 262 +S A + LL+ + + +A G + R+ + NL + + Sbjct: 302 YSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQI 353 >6CUD-A nrPDB Length = 806 Score = 32.0 bits (71), Expect = 0.86, Method: Composition-based stats. Identities = 24/205 (11%), Positives = 63/205 (30%), Gaps = 39/205 (19%) Query: 487 KVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTL-----AVYRLPHPGWRPEMVGL--LS 539 +++ G R Y+ NV D + + + + A + + L ++ Sbjct: 443 ELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVT 502 Query: 540 LWDMTRMLNMLI-----------------------VFRFLRIIPSMKLMAVVASTVLGLV 576 L + R I+P+ + + ++ V Sbjct: 503 LPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV 562 Query: 577 QNMRAFGGILVVVYYVFAI---------IGINLFRGVIVALPGNSSLAPANGSAPCGSFE 627 +++ F + ++V++ F I +G + +L + + Sbjct: 563 KDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSV 622 Query: 628 QLEYWANNFDDFAAALVTLWNLMVV 652 L+Y ++ L ++N+ +V Sbjct: 623 VLKYDHKFIENIGYVLYGIYNVTMV 647 >5MRF-DD nrPDB Length = 486 Score = 30.9 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 21/45 (46%), Gaps = 3/45 (6%) Query: 697 FLHKWDPRSHLQPLAGTP---EATYQMTVELLFRDILEEPGEDEL 738 F W PR L P A P E +++ + RD + PG+ E+ Sbjct: 421 FFTPWKPRPFLSPFAILPHHLEISFKTCHAVYLRDPVARPGQSEV 465 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.321 0.128 0.333 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,817,415 Number of Sequences: 36641 Number of extensions: 960877 Number of successful extensions: 3382 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 44 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 3127 Number of HSP's gapped (non-prelim): 128 length of query: 752 length of database: 10,336,785 effective HSP length: 104 effective length of query: 648 effective length of database: 6,526,121 effective search space: 4228926408 effective search space used: 4228926408 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 63 (28.9 bits)