BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8NB78 (822 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4FWE-A nrPDB 1667 0.0 3ABT-A nrPDB 207 1e-53 5L3D-A nrPDB 206 2e-53 3L1R-A nrPDB 148 1e-35 2BK5-A nrPDB 94 2e-19 2BXR-A nrPDB 93 4e-19 1O5W-A nrPDB 91 2e-18 3RHA-A nrPDB 83 6e-16 3BI4-A nrPDB 82 9e-16 3KVE-A nrPDB 61 2e-09 3NK2-X nrPDB 60 4e-09 6CR0-A nrPDB 57 2e-08 2JB2-A nrPDB 56 7e-08 1F8S-A nrPDB 49 7e-06 1REO-A nrPDB 49 8e-06 2VVL-G nrPDB 47 3e-05 4IV9-A nrPDB 45 1e-04 1SEZ-A nrPDB 42 8e-04 3K30-A nrPDB 42 0.001 3LXD-A nrPDB 42 0.001 5MOG-A nrPDB 42 0.002 4DGK-A nrPDB 42 0.002 1I8T-A nrPDB 41 0.002 3WE0-A nrPDB 41 0.002 5NMX-A nrPDB 40 0.004 3KYB-A nrPDB 39 0.006 5JFC-L nrPDB 38 0.016 5VJ7-A nrPDB 38 0.016 4A6N-B nrPDB 37 0.034 4Y4M-A nrPDB 37 0.039 2TMD-A nrPDB 37 0.040 4X4J-A nrPDB 37 0.045 2QA2-A nrPDB 36 0.060 3LOV-A nrPDB 36 0.068 3I6D-A nrPDB 36 0.074 1PS9-A nrPDB 35 0.12 6C6P-A nrPDB 35 0.14 2CVJ-A nrPDB 34 0.23 4Y4N-A nrPDB 34 0.25 4IVM-B nrPDB 34 0.25 6J0Z-C nrPDB 34 0.25 4YRY-B nrPDB 34 0.27 1RP0-A nrPDB 34 0.27 1NHQ-A nrPDB 34 0.28 1DOD-A nrPDB 34 0.28 3BHF-A nrPDB 34 0.32 2YQU-A nrPDB 33 0.39 3MJ4-A nrPDB 33 0.43 3UKH-A nrPDB 33 0.43 5YGQ-A nrPDB 33 0.48 3ATQ-A nrPDB 33 0.51 1ZOV-A nrPDB 33 0.52 1V59-A nrPDB 33 0.56 3LK7-A nrPDB 33 0.58 1NAA-A nrPDB 33 0.59 4JDR-A nrPDB 33 0.66 3O0H-A nrPDB 33 0.67 3NIX-A nrPDB 33 0.68 6BRD-A nrPDB 33 0.72 4AP1-A nrPDB 33 0.75 1GPJ-A nrPDB 32 0.76 1EBD-A nrPDB 32 0.77 2GMH-A nrPDB 32 0.81 3JSK-A nrPDB 32 0.84 5GJK-A nrPDB 32 0.87 2RR4-A nrPDB 32 0.94 2R9Z-A nrPDB 32 0.95 6CMZ-A nrPDB 32 0.96 2IVE-A nrPDB 32 1.1 3NTA-A nrPDB 32 1.1 6N7F-A nrPDB 32 1.2 4OVI-A nrPDB 32 1.3 1FOH-A nrPDB 32 1.4 5KOX-A nrPDB 32 1.4 2BRY-A nrPDB 32 1.6 4TXK-A nrPDB 32 1.6 4GCM-A nrPDB 32 1.7 4K2X-A nrPDB 31 1.8 4ZCC-A nrPDB 31 1.9 5J5Z-A nrPDB 31 2.1 2Q7V-A nrPDB 31 2.1 5MJK-A nrPDB 31 2.2 2VHY-A nrPDB 31 2.2 6ACQ-A nrPDB 31 2.3 6DLL-A nrPDB 31 2.7 5TUM-A nrPDB 31 2.7 3URH-A nrPDB 30 2.9 5XIG-A nrPDB 30 2.9 4UEJ-A nrPDB 30 2.9 4ZN0-A nrPDB 30 3.2 3WPZ-A nrPDB 30 3.2 2RGJ-A nrPDB 30 3.2 1ZDL-A nrPDB 30 3.3 4CBQ-A nrPDB 30 3.4 1L1F-A nrPDB 30 3.5 5TUL-A nrPDB 30 3.6 6DU7-A nrPDB 30 3.8 3ISH-A nrPDB 30 3.9 3AB1-A nrPDB 30 4.5 3UP5-A nrPDB 30 4.8 3KKJ-A nrPDB 30 5.1 2DKH-A nrPDB 30 5.2 4NTC-A nrPDB 30 5.2 3R9U-A nrPDB 30 5.4 3IHG-A nrPDB 30 5.4 4CUK-A nrPDB 30 5.8 1S79-A nrPDB 30 6.1 4MOP-A nrPDB 29 6.6 3LAD-A nrPDB 29 6.6 4RG3-A nrPDB 29 6.9 5XGV-A nrPDB 29 7.4 3CP8-A nrPDB 29 7.9 2EQ6-A nrPDB 29 8.3 6QVI-A nrPDB 29 8.3 >4FWE-A nrPDB Length = 796 Score = 1667 bits (4317), Expect = 0.0, Method: Compositional matrix adjust. Identities = 794/796 (99%), Positives = 794/796 (99%) Query: 27 GRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLS 86 G AKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLS Sbjct: 1 GHMAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLS 60 Query: 87 CGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPE 146 CGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPE Sbjct: 61 CGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPE 120 Query: 147 CRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLI 206 CRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLI Sbjct: 121 CRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLI 180 Query: 207 LPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMN 266 LPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMN Sbjct: 181 LPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMN 240 Query: 267 RYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEAL 326 RYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEAL Sbjct: 241 RYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEAL 300 Query: 327 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI 386 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI Sbjct: 301 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI 360 Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP 446 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP Sbjct: 361 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP 420 Query: 447 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD 506 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD Sbjct: 421 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD 480 Query: 507 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA 566 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA Sbjct: 481 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA 540 Query: 567 QFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT 626 QFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT Sbjct: 541 QFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT 600 Query: 627 VPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP 686 VPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP Sbjct: 601 VPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP 660 Query: 687 SASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEV 746 SASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEV Sbjct: 661 SASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEV 720 Query: 747 PDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVT 806 PDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVT Sbjct: 721 PDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVT 780 Query: 807 GAYLSGVREASKIAAF 822 GAYLSGVREASKIAAF Sbjct: 781 GAYLSGVREASKIAAF 796 >3ABT-A nrPDB Length = 662 Score = 207 bits (528), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 123/332 (37%), Positives = 184/332 (55%), Gaps = 29/332 (8%) Query: 509 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 568 L EK++E+ S + S + Q+L +H +NLE+A + L +S + WD ++ F +F Sbjct: 333 LEEKLQELEAN--PPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDF-EF 389 Query: 569 AGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY--SGDEVQVTTTDGTG----YSAQK 622 G H + GYS + LAEGLDI+L + V+ + Y SG EV T T Y Sbjct: 390 TGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDA 449 Query: 623 VLVTVPLALL--QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 680 VL T+PL +L Q A+QF PPL E K A+ +G G + K+ L F FWD V + Sbjct: 450 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSV---NL 506 Query: 681 FGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLREL 740 FGHV + + RG +F+++ K +L++++AGEA + + D ++ +C+A L+ + Sbjct: 507 FGHVGSTTASRGELFLFWNL---YKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGI 563 Query: 741 FKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQ------------G 788 F VP P + V+RW DPW + +YS+V G SG YD++A+ I Sbjct: 564 FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIP 623 Query: 789 TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 820 +FFAGE T R++P TV GA LSG+REA +IA Sbjct: 624 RLFFAGEHTIRNYPATVHGALLSGLREAGRIA 655 Score = 103 bits (257), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 20/255 (7%) Query: 287 DVMELDELYEFPEYSRDPT----MYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 15 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 72 Query: 343 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLH 402 V V R+ ++ R GLIN G+ LP K VIIIG+G +GLAAARQL Sbjct: 73 SDTVL-VHRVHSYLERHGLINFGIYKRIKP---LPTKKTGK-VIIIGSGVSGLAAARQLQ 127 Query: 403 NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR-GAQIVNGCINNPVALMCEQLGISMHKF 461 +FG+ VT+LEA+DR+GGRV + KG V GA +V G NP+A++ +Q+ + + K Sbjct: 128 SFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKI 185 Query: 462 GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS--EWRKDKTQLQDVP--LGEKIEEIY 517 ++C L + G+ D+ ++ FN LL+ S + D L + P LG+ +E + Sbjct: 186 KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVI 245 Query: 518 KAFIKESGIQFSELE 532 + ++E ++ ++E Sbjct: 246 Q--LQEKHVKDEQIE 258 >5L3D-A nrPDB Length = 852 Score = 206 bits (525), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 122/332 (36%), Positives = 184/332 (55%), Gaps = 29/332 (8%) Query: 509 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 568 L EK++E+ S + S + Q+L +H +NLE+A + L +S + WD ++ F +F Sbjct: 504 LEEKLQELEAN--PPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDF-EF 560 Query: 569 AGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY--SGDEVQVTTTDGTG----YSAQK 622 G H + GYS + LAEGLDI+L + V+ + Y SG EV T T Y Sbjct: 561 TGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDA 620 Query: 623 VLVTVPLALL--QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 680 VL T+PL +L Q A+QF PPL E K A+ +G G + K+ L F FWD V + Sbjct: 621 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSV---NL 677 Query: 681 FGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLREL 740 FGHV + + RG +F+++ K +L++++AGEA + + D ++ +C+A L+ + Sbjct: 678 FGHVGSTTASRGELFLFWNL---YKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGI 734 Query: 741 FKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQ------------G 788 F VP P + V+RW DPW + ++S+V G SG YD++A+ I Sbjct: 735 FGSSAVPQPKETVVSRWRADPWARGSHSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIP 794 Query: 789 TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 820 +FFAGE T R++P TV GA LSG+REA +IA Sbjct: 795 RLFFAGEHTIRNYPATVHGALLSGLREAGRIA 826 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 20/255 (7%) Query: 287 DVMELDELYEFPEYSRDP----TMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 186 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 243 Query: 343 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLH 402 V V R+ ++ R GLIN G+ LP K VIIIG+G +GLAAARQL Sbjct: 244 SDTVL-VHRVHSYLERHGLINFGIYK---RIKPLPTKKTGK-VIIIGSGVSGLAAARQLQ 298 Query: 403 NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR-GAQIVNGCINNPVALMCEQLGISMHKF 461 +FG+ VT+LEA+DR+GGRV + KG V GA +V G NP+A++ +Q+ + + K Sbjct: 299 SFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKI 356 Query: 462 GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS--EWRKDKTQLQDVP--LGEKIEEIY 517 ++C L + G+ D+ ++ FN LL+ S + D L + P LG+ +E + Sbjct: 357 KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVI 416 Query: 518 KAFIKESGIQFSELE 532 + ++E ++ ++E Sbjct: 417 Q--LQEKHVKDEQIE 429 >3L1R-A nrPDB Length = 478 Score = 148 bits (373), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 135/472 (28%), Positives = 215/472 (45%), Gaps = 67/472 (14%) Query: 385 VIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIGGRVWDDKSFKGVTVGRGA---QIVN 440 VI++GAG +G++AA++L GI + +LEA D IGGR+ +F G+ V GA + VN Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM-HKTNFAGINVELGANWVEGVN 65 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLI------QEGGRITDPTIDKRMDFHFNALLDVV 494 G NP+ + + + F D + ++GG + + KR++ L D V Sbjct: 66 GGKMNPIWPIVNST-LKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIE-----LADSV 119 Query: 495 SEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSN------------ 542 E +GEK+ A ++ S L Q L H N Sbjct: 120 EE------------MGEKLSATLHASGRDD---MSILAMQRLNEHQPNGPATPVDMVVDY 164 Query: 543 --LEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTP--GYSVIIEKLA----------- 587 +Y S ++ F+ F D + GY ++ LA Sbjct: 165 YKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSG 224 Query: 588 EGLD--IQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSE 645 + +D +QL V+ I YS V V T D + YSA V+V+ L +LQ IQF P L Sbjct: 225 KIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPT 284 Query: 646 KKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQ-K 704 K++AI + I L+FP +FW + +G +FF + ++S+RG + V+ + + Q Sbjct: 285 WKVRAIYQFDMAVYTMIFLKFPRKFW-PEGKGREFFLY---ASSRRGYYGVWQEFEKQYP 340 Query: 705 KHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQ 764 +VL+ + E + D+Q + M LR++F ++VPD T V RW +D + + Sbjct: 341 DANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYK 400 Query: 765 MAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREA 816 +S G + YD + + G V+F GE T+ H+ V GAYLSG+ A Sbjct: 401 GTFSNWPVGVNRYEYDQLRAPV-GRVYFTGEHTSEHYNGYVHGAYLSGIDSA 451 >2BK5-A nrPDB Length = 520 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 105/450 (23%), Positives = 184/450 (40%), Gaps = 37/450 (8%) Query: 393 AGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCE 452 +G+AAA+ LH+ G+ V VLEA+DR+GGR + ++ K V G V G N + + + Sbjct: 15 SGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV-GPTQNRILRLAK 73 Query: 453 QLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH--FNAL--LDVVSEWRKDKTQLQDVP 508 +LG+ +K E LI + + R F +N + LD + WR +++P Sbjct: 74 ELGLETYKVNEVERLIHH---VKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIP 130 Query: 509 LGEKIEEIYKAFIKES--GIQFSELEGQVL------QFHLSNLEYACGSNLHQVSAR--S 558 + +KA + E + EL ++ Q + + H+VSA Sbjct: 131 ----SDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFL 186 Query: 559 WDHNE-------FFAQFAGDHTLLTPGYSVIIEKLAE--GLDIQLKSPVQCIDYSGDEVQ 609 W + F G G + E++ + G ++L+ PV ID + + V Sbjct: 187 WYVKQCGGTTRIFSTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVL 246 Query: 610 VTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYR 669 V T + Y A+ V+ +P L K I FNPPL + + I + G + K + + Sbjct: 247 VETLNHEMYEAKYVISAIPPTLGMK--IHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEP 304 Query: 670 FWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQV 729 FW K D+ G + + + D P+ ++ +M I + L ++ Sbjct: 305 FWRKK----DYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER 360 Query: 730 LQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGT 789 L++ ++ E +P Y W + + Y+ G Y + Sbjct: 361 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR 420 Query: 790 VFFAGEATNRHFPQTVTGAYLSGVREASKI 819 ++FAG T H+ + GA +G R A +I Sbjct: 421 IYFAGTETATHWSGYMEGAVEAGERAAREI 450 >2BXR-A nrPDB Length = 527 Score = 93.2 bits (230), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 106/460 (23%), Positives = 177/460 (38%), Gaps = 33/460 (7%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVN 440 H V++IG G +GL+AA+ L +G+ V VLEA+DR+GGR + ++ V G V Sbjct: 12 HMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYV- 70 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDF----HFNALLDVVSE 496 G N + + ++LGI +K L+Q + T R F + A LD + Sbjct: 71 GPTQNRILRLSKELGIETYKVNVSERLVQ---YVKGKTYPFRGAFPPVWNPIAYLDYNNL 127 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVL------QFHLSNLEYACGSN 550 WR +++P E + K + EL ++ +F + S Sbjct: 128 WRTIDNMGKEIPTDAPWEAQHAD--KWDKMTMKELIDKICWTKTARRFAYLFVNINVTSE 185 Query: 551 LHQVSAR--SWDHNE-------FFAQFAGDHTLLTPGYSVIIEKLAE--GLDIQLKSPVQ 599 H+VSA W + F G G + E++ + G ++L PV Sbjct: 186 PHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVT 245 Query: 600 CIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGII 659 +D S D + + T + Y + V+ +P L K I F P L ++ + I L G + Sbjct: 246 HVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAK--IHFRPELPAERNQLIQRLPMGAV 303 Query: 660 EKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVA 719 K + + FW K D+ G + + D P +M I Sbjct: 304 IKCMMYYKEAFWKKK----DYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKAD 359 Query: 720 SVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAY 779 + L + ++ ++ QE P Y W + + Y+ G Y Sbjct: 360 RLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQY 419 Query: 780 DIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + G +FFAG T + + GA +G R A ++ Sbjct: 420 GRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREV 459 >1O5W-A nrPDB Length = 534 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 112/461 (24%), Positives = 181/461 (39%), Gaps = 35/461 (7%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD--DKSFKGVTVGRGAQI 438 H V++IG G +GLAAA+ L + I V VLEA+DR+GGR + ++ K V VG GA + Sbjct: 20 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVG-GAYV 78 Query: 439 VNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH--FNAL--LDVV 494 G N + + ++LGI +K L+Q + T R F +N L LD Sbjct: 79 --GPTQNRILRLSKELGIETYKVNVNERLVQ---YVKGKTYPFRGAFPPVWNPLAYLDYN 133 Query: 495 SEWRKDKTQLQDVPL-----GEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGS 549 + WR +++P+ +E K +K+ I +F + S Sbjct: 134 NLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDL-IDKICWTKTAREFAYLFVNINVTS 192 Query: 550 NLHQVSAR--SWDHNE-------FFAQFAGDHTLLTPGYSVIIEKLAE--GLDIQLKSPV 598 H+VSA W + F G G + E++ G ++L SPV Sbjct: 193 EPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPV 252 Query: 599 QCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGI 658 ID + D + V T + Y + V+ +P L K I F P L ++ + I L G Sbjct: 253 TYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAK--IHFKPELPPERNQLIQRLPMGA 310 Query: 659 IEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAV 718 + K + + FW K D+ G + + + D P +M I Sbjct: 311 VIKCMVYYKEAFWKKK----DYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKA 366 Query: 719 ASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEA 778 + L ++ ++ QE P Y W + + Y+ G Sbjct: 367 DRLAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQ 426 Query: 779 YDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 Y + G ++FAG T + + GA +G R A ++ Sbjct: 427 YGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREV 467 >3RHA-A nrPDB Length = 482 Score = 82.8 bits (203), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 113/479 (23%), Positives = 197/479 (41%), Gaps = 78/479 (16%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 ++ V+I+GAGP+GL AAR+L G+ V VLEA+DR+GGR W D + G + G Q V+ Sbjct: 7 DRDVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGRTWTD-TIDGAMLEIGGQWVS- 64 Query: 442 CINNPVALM--CEQLGISM---HKFGERCDLIQEGGRI--------TDPTIDKRMDFHFN 488 + LM ++LG+ M ++ GE + +G R + T MD Sbjct: 65 --PDQTVLMELLDELGLKMYSRYRDGESVYIGADGKRTQYTGDTFPVNETTKAEMD-KLV 121 Query: 489 ALLDVVSEWRKDKTQLQDVPLGEKIEEI-YKAFIKESGIQFSELEGQVLQFHLSNLEYAC 547 A+LD ++ T+ P +++ I + +++++ SN E AC Sbjct: 122 AILDELAA-EIGPTEPWAHPKARELDTISFHHWLRQN----------------SNDEEAC 164 Query: 548 ---------GSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGL-------- 590 G A S A AG + LT ++ +++ G+ Sbjct: 165 NNIGLFIAGGMLTKPAHAFSALQAVLMAASAGSFSHLTDEDFILDKRVIGGMQQVSLLQA 224 Query: 591 -----DIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSE 645 D+ L SPV+ I + + V V + T +A+ V++ VP L + + F+PPL Sbjct: 225 AELGDDVVLNSPVRTIKWDENGVSVVSERAT-VNARFVIMAVPPNLYSR--VSFDPPLPR 281 Query: 646 KKMKAINSLGAGIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYD-MDPQ 703 ++ + G++ K+ + FW + + G F S L YD + Sbjct: 282 RQHQMHQHQSLGLVIKVHAVYDTPFWREEGLSGTGF--------SAGALVQEVYDNTNHG 333 Query: 704 KKHSVLMSVIAGEAVASVRTL---DDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTD 760 L+ ++ E +V L D K+ + + +A F + P Y+ + W ++ Sbjct: 334 DSRGTLVGFVSDEKADAVFELSAEDRKKAILESIAG----FLGDKALTPEVYYESDWGSE 389 Query: 761 PWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 W + AY+ G Y G ++++ Q V GA G A++I Sbjct: 390 EWTRGAYASSYDLGGLHRYGKDQHANVGPIYWSSSDLAAEGYQHVDGAVRMGQATAARI 448 >3BI4-A nrPDB Length = 516 Score = 82.0 bits (201), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 129/519 (24%), Positives = 208/519 (40%), Gaps = 104/519 (20%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIK-VTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 K VIIIGAG AGL AA LH GI+ VLEA+DR+GGR+ ++G GA + Sbjct: 9 KKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHHD 68 Query: 442 CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDK 501 + NP+ L QL ++ G + + I R+D LL++V Sbjct: 69 TLTNPLFLEEAQLSLND---GRTRFVFDDDNFIYIDEERGRVDHDKELLLEIV------- 118 Query: 502 TQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVL----QFHLSN------------LEY 545 D + + E + + S F +L + L QF L+N LE Sbjct: 119 ----DNEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQF-LTNDQIRYLPQLCRYLEL 173 Query: 546 ACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLD---IQLKSPVQCID 602 G + +SA+ + +F + L Y +++++A+ ++L V+ I Sbjct: 174 WHGLDWKLLSAK----DTYFGHQGRNAFALN--YDSVVQRIAQSFPQNWLKLSCEVKSIT 227 Query: 603 YS-GDEVQVTTTDGTGYSAQKVLVTVPLALLQ---------KGAIQFNPPLSEKKMKAIN 652 V V DGT Y+A V++TVP ++L +G I+F PPL A + Sbjct: 228 REPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLKPVIQDAFD 287 Query: 653 SLGAGIIEKIALQFPYRFW---DSKV-----QGADFFGHVPPSASKRGLFAVFYDMDPQK 704 + G + K+ +F W SK+ +F V + + L ++ D QK Sbjct: 288 KIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSMLEREDSQK 347 Query: 705 KHSV--------LMSVIAGEAVASVRTL-------------DDKQVL----QQCMATLRE 739 SV +++ VAS L +DK+ L Q + + + Sbjct: 348 HTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMK 407 Query: 740 LFKEQEVPDPTK---------------YFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAE 784 ++V D + V+ W+ DP+ + AYS G + D++ Sbjct: 408 CLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPG--DDPVDMVVA 465 Query: 785 DIQGT---VFFAGEATNRHFPQTVTGAYLSGVREASKIA 820 G + FAGE T GA+ SG REA++I+ Sbjct: 466 MSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREATRIS 504 >3KVE-A nrPDB Length = 486 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 112/465 (24%), Positives = 188/465 (40%), Gaps = 75/465 (16%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 L K + K V+++GAG +GL+AA L G KVTVLEA +R GGRV ++ + G Sbjct: 27 LKKTSNPKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRV---RTHRNSKEGWY 83 Query: 436 AQIVNGCINNP-----VALMCEQLGISMHKFGERCD--------LIQEGGRIT-DPTIDK 481 A + G + P V + G+++++F + D + + G + DP + K Sbjct: 84 ANL--GPMRIPEKHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVNKDPGLLK 141 Query: 482 RMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYK---AFIKESGIQFSELEGQVLQF 538 SE K QL + LG ++++ + ++I +S E + + Sbjct: 142 --------YPVKPSEEGKSAGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEG 193 Query: 539 HLS-NLEYACGSNLHQVSA------RSWDHNEFFAQ-------FAGDHTLLTPGYSVIIE 584 +LS G L++ S S H++ FA G L T Y I E Sbjct: 194 NLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDQLPTSMYRAIEE 253 Query: 585 KLAEGLDIQLKSPVQCIDYSGDEVQVT----TTDGTGYSAQKVLVTVPLALLQKGAIQFN 640 K ++ + V I + ++V VT D + +A V+V ++ IQF Sbjct: 254 K------VKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVCTTSRAARR--IQFE 305 Query: 641 PPLSEKKMKAINSLGAGIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYD 699 PPL KK A+ S+ KI L +FW D + G +P ++Y Sbjct: 306 PPLPPKKQHALRSVHYRSGTKIFLTCSSKFWEDDGIHGGKSTTDLPSR-------FIYY- 357 Query: 700 MDPQKKHSVLMSVIAGEAVA-------SVRTLDDKQVLQQCMATLRELFKEQEVPDPTKY 752 P S + VI + +++ D ++ ++ + +L KE+ Sbjct: 358 --PNHNFSTGVGVIIAYGIGDDANFFQALKFKDCADIVFNDLSLIHQLPKEEIQSFCYPS 415 Query: 753 FVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEAT 797 + +WS D + A + T + + QG +FFAGE T Sbjct: 416 MIQKWSLDKYAMGAITTF-TPYQFQRFSEALTAPQGRIFFAGEYT 459 >3NK2-X nrPDB Length = 431 Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 70/291 (24%), Positives = 123/291 (42%), Gaps = 43/291 (14%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW--DDKSFKGVTVGRGAQIVNGCI 443 I++G G +GL AAR L N G KV +LE +R+GGR + + ++ G+ V G ++ Sbjct: 5 IVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLHRKH 64 Query: 444 NNPVALMCEQLGISM----------HKFG----ERCDLI--QEGGRITDPTIDKRMDFHF 487 + +A ++ GI H+ G ++ I E + T D H Sbjct: 65 HPRLAAELDRYGIPTAAASEFTSFRHRLGPTAVDQAFPIPGSEAVAVEAATYTLLRDAH- 123 Query: 488 NALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYAC 547 +D+ + D+PL E ++++ +L QF L+ Sbjct: 124 --RIDLEKGLENQDLEDLDIPLNEYVDKL-------------DLPPVSRQFLLAWAWNML 168 Query: 548 GSNLHQVSAR------SWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGL-DIQLKSPVQC 600 G Q SA + H + + G + +++ +++ + +I+L++ V Sbjct: 169 GQPADQASALWMLQLVAAHHYSILGVVLSLDEVFSNGSADLVDAMSQEIPEIRLQTVVTG 228 Query: 601 IDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAI 651 ID SGD V VT DG + A V+V P+ ++ I F P L E++ I Sbjct: 229 IDQSGDVVNVTVKDGHAFQAHSVIVATPMNTWRR--IVFTPALPERRRSVI 277 >6CR0-A nrPDB Length = 440 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 98/466 (21%), Positives = 183/466 (39%), Gaps = 71/466 (15%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINN 445 I++GAG +GL AAR+L G V ++EA+ R+GGR +F G V G V+ C + Sbjct: 12 IVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRT-HVVNFLGRPVEIGGAGVHWCQPH 70 Query: 446 PVALMCEQLGISMHKFGERCDL------IQEGGRITDP--TIDKRMDFHFNALLDVVSEW 497 A M ++ G K DL +G +I P T D+ F E Sbjct: 71 VFAEM-QRYGFGF-KEAPLADLDKAYMVFADGQKIDVPPATFDEEYTTAFEKFCSRSREL 128 Query: 498 ---------RKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFH---LSNLEY 545 + + L V + +E + + +Q + + ++ + + L Y Sbjct: 129 FPRPYSPLDNHEVSNLDGVSARDHLESL-----GLNELQLASMNAELTLYGGAPTTELSY 183 Query: 546 ACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEG--LDIQLKSPVQCIDY 603 H ++ SWD F H + G + + + + + D + PV+ + Sbjct: 184 PSFVKFHALA--SWDTITFTDSEKRYH--VQGGTNALCQAIFDDCRADSEFGVPVEAVAQ 239 Query: 604 SGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIA 663 + + V VT D + A ++T+P + ++F PPL +K IE Sbjct: 240 TDNGVTVTLADKRVFRALTCVLTLPTKVYAD--VRFEPPLPPEKR--------AFIEHAE 289 Query: 664 LQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASV-- 721 + GA+ + HV ++ L F D + + + + + ++ Sbjct: 290 M----------ADGAELYVHV-----RQNLGNTFTFCDDPNPFNAVQTYAYDDELGTILK 334 Query: 722 -----RTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSG 776 ++L + + A +R++ + EV + Y W+ D + + +Y ++ G Sbjct: 335 ITIGRQSLINLENFDAIAAEIRKIHGDVEVLEALPY---NWAMDEYARTSYPAMRKGWFS 391 Query: 777 EAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF 822 D+ + +FFAG AT + + + GA SG+R +I F Sbjct: 392 RYKDMAKP--ENRLFFAGSATADGWHEYIDGAIESGIRVGREIRHF 435 >2JB2-A nrPDB Length = 489 Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 97/440 (22%), Positives = 169/440 (38%), Gaps = 63/440 (14%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW------DDKSFK 428 L+ K + SV+++G GPAGL +A +L G KVTVLEA+ R GGRVW ++ Sbjct: 4 LIGKVKGSHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGRVWTARGGSEETDLS 63 Query: 429 G----VTVGRGAQIVNGCINNPVALM----CEQLGISMHKFGE---------RCDLIQEG 471 G T G G P + + C +LG+ + FG + D G Sbjct: 64 GETQKCTFSEGHFYNVGATRIPQSHITLDYCRELGVEIQGFGNQNANTFVNYQSDTSLSG 123 Query: 472 GRITDPTIDKRMDFHFNALLDVVSEW--------RKDKTQLQDV--PLGEKIEEIYKAFI 521 +T + + LL ++ R+DK L + G+ ++ ++ Sbjct: 124 QSVTYRAAKADTFGYMSELLKKATDQGALDQVLSREDKDALSEFLSDFGDLSDD--GRYL 181 Query: 522 KESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLL--TP-- 577 S + G L F +A Q RS F F D ++ TP Sbjct: 182 GSSRRGYDSEPGAGLNFGTEKKPFAM-----QEVIRSGIGRNFSFDFGYDQAMMMFTPVG 236 Query: 578 GYSVIIEKLAEGL---DIQLKSPVQCIDYSGDEVQVTTTDG---TGYSAQKVLVTVPLAL 631 G I + + +I + V + + V V T G +A + T+P L Sbjct: 237 GMDRIYYAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTIPPHL 296 Query: 632 LQKGAIQFNPP---LSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSA 688 + G +Q N P L+ K +S G K+ +++ R+W+++ + +G + Sbjct: 297 V--GRLQNNLPGDVLTALKAAKPSSSG-----KLGIEYSRRWWETEDR---IYGGASNTD 346 Query: 689 SKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPD 748 YD + V+ +G+ + +L +Q L + +A E+ E+ D Sbjct: 347 KDISQIMFPYDHYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEGSEIHGEKYTRD 406 Query: 749 PTKYFVTRWSTDPWIQMAYS 768 + F W + + A++ Sbjct: 407 ISSSFSGSWRRTKYSESAWA 426 >1F8S-A nrPDB Length = 498 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 101/449 (22%), Positives = 181/449 (40%), Gaps = 57/449 (12%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 K V+I+GAG AGL+AA L G +VTVLEA +R GGRV ++++ G A + G Sbjct: 34 KHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRV---RTYRNEEAGWYANL--GP 88 Query: 443 INNP-----VALMCEQLGISMHKFGERCD--------LIQEGGRI-TDPTIDKRMDFHFN 488 + P V + + +++F + D + ++ G + DP + + + Sbjct: 89 MRLPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGL---LKYPVK 145 Query: 489 ALLDVVSEWRKDKTQLQDVPLGEKIEEIYK---AFIKESGIQFSELEGQVLQFHLS-NLE 544 SE K QL + LG+ +EE+ + ++I +S E + + LS Sbjct: 146 P-----SEAGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLSPGAV 200 Query: 545 YACGSNLHQVSA------RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPV 598 G L++ S S H++ FA + + G + + + ++ Sbjct: 201 DMIGDLLNEDSGYYVSFIESLKHDDIFA-YEKRFDEIVDGMDKLPTAMYRDIQDKVHFNA 259 Query: 599 QCIDYSGDEVQVTTTDGT------GYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAIN 652 Q I ++ +VT T +A V+V ++ I+FNPPL KK A+ Sbjct: 260 QVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCTTSRAVR--LIKFNPPLLPKKAHALR 317 Query: 653 SLGAGIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMS 711 S+ KI L +FW D + G +P F + + + V+++ Sbjct: 318 SVHYRSGTKIFLTCTTKFWEDDGIHGGKSTTDLPSR------FIYYPNHNFTNGVGVIIA 371 Query: 712 VIAGEAVASVRTLDDK---QVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYS 768 G+ + LD K ++ ++ + +L K+ + +WS D + + Sbjct: 372 YGIGDDANFFQALDFKDCADIVFNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYAMGGIT 431 Query: 769 FVKTGGSGEAYDIIAEDIQGTVFFAGEAT 797 D + QG ++FAGE T Sbjct: 432 TFTPYQFQHFSDPLTAS-QGRIYFAGEYT 459 >1REO-A nrPDB Length = 486 Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 81/326 (24%), Positives = 135/326 (41%), Gaps = 45/326 (13%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 K V+++GAG +GL+AA L G +VTVLEA +R GGRV ++ K + Sbjct: 34 KHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLGPMRLPE 93 Query: 443 INNPVALMCEQLGISMHKFGERCD--------LIQEGGRI-TDPTIDKRMDFHFNALLDV 493 + V + G+ +++F + D + + G + DP + + + Sbjct: 94 KHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVKKDPGV---LKYPVKP---- 146 Query: 494 VSEWRKDKTQLQDVPLGEKIEEIYK---AFIKESGIQFSELEGQVLQFHLS-NLEYACGS 549 SE K QL + LG+ +EE+ + ++I +S E + + +LS G Sbjct: 147 -SEEGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDMIGD 205 Query: 550 NLHQVSA------RSWDHNEFFAQ-------FAGDHTLLTPGYSVIIEKL---AEGLDIQ 593 +++ S S H++ FA G L T Y I EK+ A+ + IQ Sbjct: 206 LMNEDSGYYVSFPESLRHDDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQ 265 Query: 594 LKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINS 653 + + Y Q + +A V+V ++ I+F PPL KK A+ S Sbjct: 266 KNAEKVTVVY-----QTPAKEMASVTADYVIVCTTSRATRR--IKFEPPLPPKKAHALRS 318 Query: 654 LGAGIIEKIALQFPYRFW-DSKVQGA 678 + KI L +FW D + G Sbjct: 319 VHYRSGTKIFLTCTKKFWEDEGIHGG 344 >2VVL-G nrPDB Length = 495 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 22/38 (57%), Positives = 25/38 (65%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW 422 VI+IG G GL A R L G K +LEA+DRIGGR W Sbjct: 42 VIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSW 79 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Query: 597 PVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGA 656 PV+ + D +VT DG + A++V+ T+PL +L IQF+P LS +++ A+ + Sbjct: 278 PVRSVVNERDAARVTARDGREFVAKRVVCTIPLNVLS--TIQFSPALSTERISAMQAGHV 335 Query: 657 GIIEKI 662 + K+ Sbjct: 336 SMCTKV 341 >4IV9-A nrPDB Length = 557 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/39 (58%), Positives = 29/39 (74%), Gaps = 1/39 (2%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVL-EAKDRIGGRVW 422 V I+GAG +GL AA +L G+K VL E++DRIGGRVW Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVW 79 >1SEZ-A nrPDB Length = 504 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 24/58 (41%), Positives = 35/58 (60%), Gaps = 11/58 (18%) Query: 378 KDYHN--KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR---------VWDD 424 +D H+ K V +IGAG +GLAAA +L G+ VTV EA+ + GG+ +WD+ Sbjct: 7 EDKHSSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDE 64 >3K30-A nrPDB Length = 690 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 31/50 (62%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVT 431 + V+++GAGP+GL AAR L G V + EA +GGRV + + G++ Sbjct: 391 DARVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRVTQESALPGLS 440 >3LXD-A nrPDB Length = 415 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 22/51 (43%), Positives = 30/51 (58%) Query: 371 ADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 AD+ + D K+ ++IG G GL AA L FG+ VT+LEA R+ RV Sbjct: 141 ADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARV 191 >5MOG-A nrPDB Length = 497 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCIN 444 V+I GAG AGL+ A+ L + G K +LEA+D +GG++ K G G I G Sbjct: 20 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGAYP 79 Query: 445 NPVALMCEQLGIS 457 N L E LGI+ Sbjct: 80 NIQNLFGE-LGIN 91 >4DGK-A nrPDB Length = 501 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 7/76 (9%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR--VWDDKSFKGVTVGRGAQIVN 440 K +IGAG GLA A +L GI V +LE +D+ GGR V++D+ F T G ++ Sbjct: 2 KPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGF---TFDAGPTVIT 58 Query: 441 --GCINNPVALMCEQL 454 I AL +QL Sbjct: 59 DPSAIEELFALAGKQL 74 >1I8T-A nrPDB Length = 367 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 73/273 (26%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR-GAQI------ 438 II+G+G G A +L KV V+E ++ IGG + + +G+ + + GA I Sbjct: 5 IIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDC-EGIQIHKYGAHIFHTNDK 63 Query: 439 -----------VNGCINNPVALMCEQLG---ISMHKFGERCDLI--QEGGRITDPTIDKR 482 N N+P+A+ ++L +M+ F + + QE I + K Sbjct: 64 YIWDYVNDLVEFNRFTNSPLAIYKDKLFNLPFNMNTFHQMWGVKDPQEAQNIINAQKKKY 123 Query: 483 MDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFI-----KESGIQFSELEGQVLQ 537 D K L++ + E++Y+A I K+ G EL +++ Sbjct: 124 GD--------------KVPENLEEQAISLVGEDLYQALIKGYTEKQWGRSAKELPAFIIK 169 Query: 538 FHLSNLEYACGSNLHQVSAR-SWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKS 596 ++ R ++D+N F ++ G + GY+ +IEK+ EG+D++L Sbjct: 170 ---------------RIPVRFTFDNNYFSDRYQG---IPVGGYTKLIEKMLEGVDVKL-- 209 Query: 597 PVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPL 629 ID+ D+ D A +++ T P+ Sbjct: 210 ---GIDFLKDK------DSLASKAHRIIYTGPI 233 >3WE0-A nrPDB Length = 580 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 2/55 (3%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGV 430 +P H + V I+GAG AGL AA +L G+K V EA ++GGR+ ++F G Sbjct: 59 IPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEAS-KMGGRL-RSQAFNGT 111 >5NMX-A nrPDB Length = 425 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 423 + V ++GAGP+GL AAR L G +V V E +GG W+ Sbjct: 2 RRVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGG-TWN 41 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 20/31 (64%) Query: 371 ADQYLLPKDYHNKSVIIIGAGPAGLAAARQL 401 A ++ P+ + NK V+I+GAGP+G A + Sbjct: 173 AHEFRSPEPFRNKRVLIVGAGPSGHDMALHI 203 >3KYB-A nrPDB Length = 390 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 28/44 (63%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDK 425 +K ++I+GAG +G RQL G +V +++ +D IGG +D + Sbjct: 3 SKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDAR 46 >5JFC-L nrPDB Length = 474 Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 5/55 (9%) Query: 370 GADQYLLPKDY-----HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 G D LL ++ + K V IIGAGPAGL A L G +VT+ EA + GG Sbjct: 137 GIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG 191 >5VJ7-A nrPDB Length = 476 Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 5/55 (9%) Query: 370 GADQYLLPKDY-----HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 G D LL ++ + K V IIGAGPAGL A L G +VT+ EA + GG Sbjct: 137 GIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG 191 >4A6N-B nrPDB Length = 398 Score = 37.0 bits (84), Expect = 0.034, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query: 375 LLPKDYH-----NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW 422 L+P+ H +K+V IIG GP GL A+ L GI V+V E + R++ Sbjct: 14 LVPRGSHMNLLSDKNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIF 66 >4Y4M-A nrPDB Length = 290 Score = 37.0 bits (84), Expect = 0.039, Method: Compositional matrix adjust. Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 3/47 (6%) Query: 366 VLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 +L D +L D V+I+GAGP+GL AR L G KV VLE Sbjct: 46 ILKASFDMWL---DIVEADVVIVGAGPSGLTCARYLAKEGFKVVVLE 89 >2TMD-A nrPDB Length = 729 Score = 37.0 bits (84), Expect = 0.040, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 25/38 (65%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 SV+I+GAGP+G AAR L G V + + ++IGG + Sbjct: 391 SVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHL 428 >4X4J-A nrPDB Length = 507 Score = 36.6 bits (83), Expect = 0.045, Method: Compositional matrix adjust. Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 1/39 (2%) Query: 375 LLPKDYH-NKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 L+P+ H + V+I GAGPAGL A +L GI V VLE Sbjct: 14 LVPRGSHMDAPVVIAGAGPAGLMLAGELRLAGIGVVVLE 52 >2QA2-A nrPDB Length = 499 Score = 36.2 bits (82), Expect = 0.060, Method: Compositional matrix adjust. Identities = 17/31 (54%), Positives = 22/31 (70%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 + SVI++GAGPAGL A +L G+ V VLE Sbjct: 12 DASVIVVGAGPAGLMLAGELRLGGVDVMVLE 42 >3LOV-A nrPDB Length = 475 Score = 36.2 bits (82), Expect = 0.068, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 3/56 (5%) Query: 382 NKSVIIIGAGPAGLAAARQLHNF--GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 +K ++I+G G GLAAA + +T+LEA +R+GG+V + G T+ RG Sbjct: 4 SKRLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYRE-DGFTIERG 58 >3I6D-A nrPDB Length = 470 Score = 35.8 bits (81), Expect = 0.074, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Query: 383 KSVIIIGAGPAGLAAARQLH------NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 K V+IIG G GLAAA + N +++T++EA R+GG++ K G + RG Sbjct: 6 KHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKK-DGYIIERG 63 >1PS9-A nrPDB Length = 671 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKG 429 +LP K++ ++GAGPAGLA A G +VT+ +A IGG+ K G Sbjct: 367 ILPA-VQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPG 420 >6C6P-A nrPDB Length = 458 Score = 35.0 bits (79), Expect = 0.14, Method: Compositional matrix adjust. Identities = 28/73 (38%), Positives = 33/73 (45%), Gaps = 12/73 (16%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK----DRIGG--------RVWDDKSFK 428 ++ VII+GAG G A A L G KVTV+E DRI G V D Sbjct: 6 NDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLG 65 Query: 429 GVTVGRGAQIVNG 441 G AQ+VNG Sbjct: 66 DTVEGLDAQVVNG 78 >2CVJ-A nrPDB Length = 180 Score = 34.3 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 9/47 (19%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVT 431 VI++G GP+GL+AA L G+KV VL+ GGR KGV+ Sbjct: 4 VIVVGGGPSGLSAALFLARAGLKVLVLD-----GGR----SKVKGVS 41 >4Y4N-A nrPDB Length = 286 Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust. Identities = 17/34 (50%), Positives = 21/34 (61%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 D + V I+G GP+GL AAR + G KV VLE Sbjct: 49 DIIDVDVAIVGGGPSGLTAARYIAKEGYKVVVLE 82 >4IVM-B nrPDB Length = 483 Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGI--KVTVLEAKDRIGGRVWDDKSFKGVT--VGRGAQ 437 ++V+++G G +GLAA+ L KV ++E+ +R+GG + + G +G G Sbjct: 8 GRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPGGI 67 Query: 438 IVNGCINNPVALMCEQLGISMHKFGERCD 466 G + L+ +LG+ R D Sbjct: 68 RPAGALGARTLLLVSELGLDSEVLPVRGD 96 >6J0Z-C nrPDB Length = 491 Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 23/34 (67%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 ++++ V+++GAGP GL A +L G+ V VL+ Sbjct: 2 EFYDSDVVVVGAGPTGLMLAGELRLAGVSVVVLD 35 >4YRY-B nrPDB Length = 468 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 22/37 (59%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 + V ++G+GPAGL AA L G V + EA + GG Sbjct: 141 EKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGG 177 >1RP0-A nrPDB Length = 284 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 13/80 (16%) Query: 380 YHNKSVIIIGAGPAGLAAARQLH-NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQI 438 Y V+++GAG AGL+AA ++ N ++V ++E GG W G Q+ Sbjct: 37 YAETDVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW-----------LGGQL 85 Query: 439 VNGCI-NNPVALMCEQLGIS 457 + I P L +++G++ Sbjct: 86 FSAMIVRKPAHLFLDEIGVA 105 >1NHQ-A nrPDB Length = 447 Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust. Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGV 430 +V++IG+G G+ AA G KVTV++ DR G V+ DK F V Sbjct: 151 NVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLG-VYLDKEFTDV 196 >1DOD-A nrPDB Length = 394 Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust. Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 2/39 (5%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAK--DRIGGRV 421 V IIGAGP+GL + LH GI +LE + D + GR+ Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRI 43 >3BHF-A nrPDB Length = 390 Score = 33.9 bits (76), Expect = 0.32, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 25/158 (15%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKD--RIGGRVWDDKSFKGVTVGRGAQIVNGC 442 VI++GAG G+AA QL G+K +++A D G D G G + V Sbjct: 7 VIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYV--- 63 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKT 502 P+AL ++L + K + G + P + +A + E K+ + Sbjct: 64 ---PLALRSQELWYELEKETHHKIFTKTGVLVFGPKGE-------SAFVAETMEAAKEHS 113 Query: 503 QLQDVPLGEKIE---------EIYKA-FIKESGIQFSE 530 D+ G++I E Y A F SG+ FSE Sbjct: 114 LTVDLLEGDEINKRWPGITVPENYNAIFEPNSGVLFSE 151 >2YQU-A nrPDB Length = 455 Score = 33.5 bits (75), Expect = 0.39, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 23/35 (65%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 +++IGAGP G AA + G+KV V+E + +GG Sbjct: 4 LLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGG 38 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 19/35 (54%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 K +I++G G GL H G +V VLE DRI Sbjct: 168 KRLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRI 202 >3MJ4-A nrPDB Length = 397 Score = 33.5 bits (75), Expect = 0.43, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 27/47 (57%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTV 432 +I+GAG AG A +L + G +V +++ + IGG +D GV + Sbjct: 33 LIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYDDAGVLI 79 >3UKH-A nrPDB Length = 519 Score = 33.5 bits (75), Expect = 0.43, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 385 VIIIGAGPAGLAAARQLHNF-GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 V++IGAGP GL AA++L+ G ++++ + GG D + +G G ++ Sbjct: 9 VLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVTPEGFLYDVGGHVI 64 >5YGQ-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.48, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 24/36 (66%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR 420 V+I+GAGP GL A +L +K +++ D++GG+ Sbjct: 9 VLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQ 44 >3ATQ-A nrPDB Length = 453 Score = 33.1 bits (74), Expect = 0.51, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 27/38 (71%), Gaps = 2/38 (5%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAK--DRIGGR 420 V+IIG G AG +AA QL G+K+ ++++K +RIG + Sbjct: 9 VLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDK 46 >1ZOV-A nrPDB Length = 386 Score = 33.1 bits (74), Expect = 0.52, Method: Compositional matrix adjust. Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 17/154 (11%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKD--RIGGRVWDDKSFKGVTVGRGAQIVNGC 442 VI++GAG G+AA L G+K ++++ D G D G G + V Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYV--- 62 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPT-----IDKRMDFHFNALLDVVSEW 497 P AL ++L + K Q G + P + + M+ A + + Sbjct: 63 ---PFALRAQELWYELEKETHHKIFTQTGVLVYGPKGGSAFVSETME---AANIHSLEHE 116 Query: 498 RKDKTQLQDVPLGEKIEEIYKA-FIKESGIQFSE 530 + QL D G ++ + Y+A F SG+ FSE Sbjct: 117 LFEGKQLTDRWAGVEVPDNYEAIFEPNSGVLFSE 150 >1V59-A nrPDB Length = 478 Score = 33.1 bits (74), Expect = 0.56, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 382 NKS--VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 NKS V+IIG GPAG AA + G +E + ++GG Sbjct: 3 NKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGG 42 >3LK7-A nrPDB Length = 451 Score = 32.7 bits (73), Expect = 0.58, Method: Compositional matrix adjust. Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 19/126 (15%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 + NK V+++G +G AAAR L G VTV + G+ +D+ + G ++V Sbjct: 7 FENKKVLVLGLARSGEAAARLLAKLGAIVTVND------GKPFDENPTAQSLLEEGIKVV 60 Query: 440 NGCINNPVALMCEQLGISMHKFGERCDLIQEGGR-ITDPTIDKRMDFHFNALLDVVSEWR 498 C ++P+ L+ E C +I+ G +P + K ++ L +V + Sbjct: 61 --CGSHPLELLDEDF----------CYMIKNPGIPYNNPMVKKALEKQIPVLTEVELAYL 108 Query: 499 KDKTQL 504 ++QL Sbjct: 109 VSESQL 114 >1NAA-A nrPDB Length = 541 Score = 32.7 bits (73), Expect = 0.59, Method: Compositional matrix adjust. Identities = 18/36 (50%), Positives = 22/36 (61%), Gaps = 5/36 (13%) Query: 377 PKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 P DY II+GAGP G+ AA +L G KV +LE Sbjct: 2 PYDY-----IIVGAGPGGIIAADRLSEAGKKVLLLE 32 >4JDR-A nrPDB Length = 474 Score = 32.7 bits (73), Expect = 0.66, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 25/35 (71%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 V+++GAGPAG +AA + + G++ ++E + +GG Sbjct: 9 VVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGG 43 >3O0H-A nrPDB Length = 484 Score = 32.7 bits (73), Expect = 0.67, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 20/35 (57%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 KS++I+G G G+ A H G+K T+L D I Sbjct: 192 KSIVIVGGGYIGVEFANIFHGLGVKTTLLHRGDLI 226 >3NIX-A nrPDB Length = 421 Score = 32.7 bits (73), Expect = 0.68, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 20/28 (71%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 V++IGAGPAG AA ++ G KV ++E Sbjct: 8 VLVIGAGPAGTVAASLVNKSGFKVKIVE 35 >6BRD-A nrPDB Length = 476 Score = 32.7 bits (73), Expect = 0.72, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 19/28 (67%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 VI++G GP GL A +L G++V VLE Sbjct: 4 VIVVGGGPTGLMLAGELRLHGVRVLVLE 31 >4AP1-A nrPDB Length = 549 Score = 32.7 bits (73), Expect = 0.75, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW 422 V+++GAG AGL A + + G+ V EA +GG VW Sbjct: 24 VVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGG-VW 60 >1GPJ-A nrPDB Length = 404 Score = 32.3 bits (72), Expect = 0.76, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 4/54 (7%) Query: 362 INTGVLSVGADQYLLPK----DYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVL 411 I+ G +S+G+ L + H+K+V+++GAG G A+ L + G++ ++ Sbjct: 143 ISEGAVSIGSAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLV 196 >1EBD-A nrPDB Length = 455 Score = 32.3 bits (72), Expect = 0.77, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 20/35 (57%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 KS+++IG G G+ NFG KVT+LE I Sbjct: 171 KSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEI 205 Score = 30.4 bits (67), Expect = 3.0, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 +++GAGP G AA + G KVT++E K +GG Sbjct: 7 LVVGAGPGGYVAAIRAAQLGQKVTIVE-KGNLGG 39 >2GMH-A nrPDB Length = 584 Score = 32.3 bits (72), Expect = 0.81, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 11/55 (20%) Query: 385 VIIIGAGPAGLAAARQL------HNFGIKVTVLEAKDRIG-----GRVWDDKSFK 428 V+I+GAGPAGL+AA +L H ++V ++E IG G D ++F+ Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACLDPRAFE 92 >3JSK-A nrPDB Length = 344 Score = 32.3 bits (72), Expect = 0.84, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 373 QYLLPKDYHNKS-VIIIGAGPAGLAAARQLHNF--GIKVTVLEAKDRIGGRVW 422 +Y D H ++ ++I+GAG GL+AA L +++T++EA GG W Sbjct: 69 RYFADLDAHAETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW 121 >5GJK-A nrPDB Length = 94 Score = 32.3 bits (72), Expect = 0.87, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 7/76 (9%) Query: 291 LDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVE 350 L E + S+ P +YLA RN ++ + N +E LT C R L C V Sbjct: 25 LPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTAC-----RRNLTGDVCA--VM 77 Query: 351 RILYFMTRKGLINTGV 366 R+ F+ + GL+N V Sbjct: 78 RVHAFLEQWGLVNYQV 93 >2RR4-A nrPDB Length = 69 Score = 32.3 bits (72), Expect = 0.94, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 6/52 (11%) Query: 139 WVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPED 190 WVQC+ P C KWR+L I + + + C NT ++ + C +PE+ Sbjct: 18 WVQCSFPNCGKWRRLCGNIDPS-VLPDNWSCDQ--NTDVQ---YNRCDIPEE 63 >2R9Z-A nrPDB Length = 463 Score = 32.3 bits (72), Expect = 0.95, Method: Compositional matrix adjust. Identities = 17/35 (48%), Positives = 23/35 (65%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 K V IIGAG G+ A L +FG +VTV+ +DR+ Sbjct: 167 KRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRL 201 >6CMZ-A nrPDB Length = 466 Score = 32.3 bits (72), Expect = 0.96, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 2/42 (4%) Query: 378 KDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 K+ H ++++IG GP G AA + GI TVL +DR+GG Sbjct: 5 KNEHT-TLLVIGGGPGGYVAAIRAGQLGIP-TVLVERDRLGG 44 >2IVE-A nrPDB Length = 478 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 23/38 (60%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 +V ++G G +GLA A L + G +LE+ R+GG V Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAV 55 >3NTA-A nrPDB Length = 574 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 19/31 (61%) Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 ++G G GL LH+ GIK T+LE D++ Sbjct: 156 VVGGGFIGLEMMESLHHLGIKTTLLELADQV 186 >6N7F-A nrPDB Length = 453 Score = 32.0 bits (71), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 6/49 (12%) Query: 371 ADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 ++ ++P DY I+IG G AG+A+A + G KV + E K+ IGG Sbjct: 1 SNAMVIPYDY-----IVIGGGSAGIASANRAAMHGAKVLLAEGKE-IGG 43 >4OVI-A nrPDB Length = 542 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW 422 V+++GAG +GL A +L G V V+E +GG VW Sbjct: 19 VLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG-VW 55 >1FOH-A nrPDB Length = 664 Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 5/35 (14%) Query: 385 VIIIGAGPAGLAAARQLHNF-----GIKVTVLEAK 414 V+I+GAGPAGL AAR L + +KV +++ + Sbjct: 10 VLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKR 44 >5KOX-A nrPDB Length = 476 Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 18/32 (56%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 H VII G GP GL A +L G++ VLE Sbjct: 3 HMIDVIIAGGGPTGLMLAGELRLHGVRTVVLE 34 >2BRY-A nrPDB Length = 497 Score = 31.6 bits (70), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 N +++GAGP GL AA +L G +V ++E + Sbjct: 92 NTKCLVVGAGPCGLRAAVELALLGARVVLVEKR 124 >4TXK-A nrPDB Length = 615 Score = 31.6 bits (70), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 N +++GAGP GL AA +L G +V ++E + Sbjct: 84 NTKCLVVGAGPCGLRAAVELALLGARVVLVEKR 116 >4GCM-A nrPDB Length = 312 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI-GGRVWDDKSFK 428 + NK + +IG G + + L F KVT++ +D + R+ D++FK Sbjct: 143 FKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFK 192 >4K2X-A nrPDB Length = 523 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 375 LLPKDYHNK-SVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 L+P+ H + V+I GAGP GL A +L G + VLE Sbjct: 14 LVPRGSHMRYDVVIAGAGPTGLMLACELRLAGARTLVLE 52 >4ZCC-A nrPDB Length = 336 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQ 437 + IIG G AGL+AA+ L + G +V + + GGR+ +S G ++ GAQ Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAG-SLDMGAQ 56 >5J5Z-A nrPDB Length = 496 Score = 31.2 bits (69), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 6/50 (12%) Query: 370 GADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 GADQ P D V +IG+GP G AA + G K +E + +GG Sbjct: 22 GADQ---PID---ADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG 65 >2Q7V-A nrPDB Length = 325 Score = 31.2 bits (69), Expect = 2.1, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 23/105 (21%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV-WDD--KSFKGVTVGRGAQ 437 H+ V+IIG GPAGL AA + +LE K GG++ W + ++F G Sbjct: 7 HDYDVVIIGGGPAGLTAAIYTGRAQLSTLILE-KGMPGGQIAWSEEVENFPG-------- 57 Query: 438 IVNGCINNPVALMCEQLGISMH----KFGERCDLIQEGGRITDPT 478 P+A M +L MH KFG + ++ + G D T Sbjct: 58 -----FPEPIAGM--ELAQRMHQQAEKFGAKVEMDEVQGVQHDAT 95 >5MJK-A nrPDB Length = 327 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 11/38 (28%), Positives = 23/38 (60%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 + N+ +++IG G + + A L FG VT++ +D++ Sbjct: 161 FRNQEILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKL 198 >2VHY-A nrPDB Length = 377 Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/28 (53%), Positives = 19/28 (67%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 V++IGAG AG AAR + G VTVL+ Sbjct: 171 VVVIGAGTAGYNAARIANGMGATVTVLD 198 >6ACQ-A nrPDB Length = 302 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 24/49 (48%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 423 L+P+ H K V +IGAG G A+ G +V + + KD R D Sbjct: 14 LVPRGSHMKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLD 62 >6DLL-A nrPDB Length = 398 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 18/28 (64%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 V IIGAGP+GL + LH GI ++E Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIVE 35 >5TUM-A nrPDB Length = 410 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 375 LLPKDYH----NKSVIIIGAGPAGLAAARQLHNFGIKVTVLE--AKDRIGGRVWD 423 L+P+ H N +++IGAG AG A L FG ++E A R GG+ D Sbjct: 14 LVPRGSHMMSKNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALD 68 >3URH-A nrPDB Length = 491 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 +I+IG+GP G A + G+KV V+E + GG Sbjct: 28 LIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGG 62 >5XIG-A nrPDB Length = 500 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 20/89 (22%), Positives = 39/89 (43%), Gaps = 5/89 (5%) Query: 675 VQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCM 734 ++ F V P+ +++ L + DP+ + + + ++ D +QV+ M Sbjct: 406 IEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGDSEQVMTGAM 465 Query: 735 ATLRELFKEQEVPDPTKYFVT-----RWS 758 TL F + +P+ TK F T RW+ Sbjct: 466 KTLCIPFDQPPMPEGTKCFYTGKPAKRWT 494 >4UEJ-A nrPDB Length = 346 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 23/41 (56%) Query: 367 LSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIK 407 ++VG + L + NK+VIIIGAG GL A + G K Sbjct: 146 ITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAK 186 >4ZN0-A nrPDB Length = 311 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 +IIIG GPAGL A +G+ +LE ++ I G++ Sbjct: 10 LIIIGGGPAGLTAGIYAVRYGLDTLILE-RNEISGQI 45 >3WPZ-A nrPDB Length = 542 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 366 VLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDK 425 + S+ AD+ L D H + I PAG+ AA + N G L K+ + G++++D+ Sbjct: 96 IFSLVADRNLGFDDRHVFAKIGYFYRPAGVPAAERPENGGWTYGGLVFKEGVTGQIFEDQ 155 Query: 426 SFKGVTVGRGAQIV--NGCIN---NPVALMCEQLGISMHKFGERCDL 467 SF T G+ V NG I VA G ++ + R L Sbjct: 156 SFSHQTQWTGSARVSKNGEIKLFFTDVAFYRNSDGTNIKPYDPRIAL 202 >2RGJ-A nrPDB Length = 402 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 385 VIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRI 417 ++I GAG GL+ A LH GI KVT+LE+ I Sbjct: 7 ILIAGAGIGGLSCALALHQAGIGKVTLLESSSEI 40 >1ZDL-A nrPDB Length = 517 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 37/191 (19%) Query: 375 LLPKDYHNKS-----------VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 423 L+P+ H S +++IG G GLA A++ G KV V + + Sbjct: 14 LVPRGSHMASASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVAD---------YV 64 Query: 424 DKSFKGVTVGRGAQIVN-GCINNPVALMCEQLGISM---HKFG-ERCDLIQEGGRITDPT 478 + S +G G G VN GCI + LG + H +G E +Q + T Sbjct: 65 EPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVAQPVQHNWK----T 120 Query: 479 IDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQF 538 + + + H +L W + QLQD + K I +F+ E ++ + G+ Sbjct: 121 MAEAVQNHVKSL-----NW-GHRVQLQDRKV--KYFNIKASFVDEHTVRGVDKGGKATLL 172 Query: 539 HLSNLEYACGS 549 ++ A G Sbjct: 173 SAEHIVIATGG 183 >4CBQ-A nrPDB Length = 314 Score = 30.4 bits (67), Expect = 3.4, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 + NK ++++G G A + A L +G KV +L +D Sbjct: 150 FRNKVLMVVGGGDAAMEEALHLTKYGSKVIILHRRD 185 >1L1F-A nrPDB Length = 505 Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 423 + +K+ ++ G G GL + R LH FG K + D G +W+ Sbjct: 246 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESD---GSIWN 286 >5TUL-A nrPDB Length = 406 Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD--RIGGRVWDDKSFKGVTVGRGAQI 438 H K +++IGA AG A L+++G + T++E R GG D +G+ V Q+ Sbjct: 24 HTKKILVIGASIAGPALCYWLNHYGFQPTLVEKNQSTRKGGYAID---LRGIAVDVAKQM 80 >6DU7-A nrPDB Length = 448 Score = 30.0 bits (66), Expect = 3.8, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDR 416 +SV I+GAG + A LH FG+K + +DR Sbjct: 167 ESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDR 200 >3ISH-A nrPDB Length = 311 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 20/35 (57%) Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 IIG GPAGL+A G+K VL K GG++ Sbjct: 6 IIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQI 40 >3AB1-A nrPDB Length = 360 Score = 30.0 bits (66), Expect = 4.5, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 379 DYHN-KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 D+H+ + + IIG GP G+ AA Q I ++E+ ++GG++ Sbjct: 10 DHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQL 53 >3UP5-A nrPDB Length = 545 Score = 30.0 bits (66), Expect = 4.8, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 22/34 (64%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 ++IGAG G+ A ++ G+KV +EA + +GG Sbjct: 13 VVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGG 46 >3KKJ-A nrPDB Length = 336 Score = 29.6 bits (65), Expect = 5.1, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQ 437 + IIG G AGL+AA+ L G +V + + GGR+ +S G + GAQ Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGA-LDMGAQ 56 >2DKH-A nrPDB Length = 639 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 1/32 (3%) Query: 385 VIIIGAGPAGLAAARQLHNF-GIKVTVLEAKD 415 V+I+G GPAGL A QL F I+ ++E K+ Sbjct: 35 VLIVGCGPAGLTLAAQLAAFPDIRTCIVEQKE 66 >4NTC-A nrPDB Length = 335 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/22 (68%), Positives = 17/22 (77%), Gaps = 4/22 (18%) Query: 385 VIIIGAGPAGLAA----ARQLH 402 V+IIGAGPAGL+ ARQLH Sbjct: 17 VLIIGAGPAGLSTATGLARQLH 38 >3R9U-A nrPDB Length = 315 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 21/37 (56%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV 421 V IIG GPAGL+A G+K V+ K GG++ Sbjct: 7 VAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQI 43 >3IHG-A nrPDB Length = 535 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 H V+++GAG GL+ A L G++V V+E + Sbjct: 4 HEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 >4CUK-A nrPDB Length = 338 Score = 29.6 bits (65), Expect = 5.8, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 H K+ +IG G G+AA R L FG+++ + Sbjct: 143 HGKTAGVIGTGKIGVAALRILKGFGMRLLAFD 174 >1S79-A nrPDB Length = 103 Score = 29.6 bits (65), Expect = 6.1, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Query: 485 FHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFI------KESGIQFSELEGQ 534 F +A LD + EW +DK Q+ ++ + + + +K I ES +F E GQ Sbjct: 19 FPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQ 74 >4MOP-A nrPDB Length = 633 Score = 29.3 bits (64), Expect = 6.6, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 V+I+G+GP G AR+L G KV + + Sbjct: 49 VVIVGSGPIGCTYARELVGAGYKVAMFD 76 >3LAD-A nrPDB Length = 476 Score = 29.3 bits (64), Expect = 6.6, Method: Compositional matrix adjust. Identities = 13/28 (46%), Positives = 18/28 (64%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 VI+IGAGP G AA + G+K ++E Sbjct: 6 VIVIGAGPGGYVAAIKSAQLGLKTALIE 33 >4RG3-A nrPDB Length = 548 Score = 29.3 bits (64), Expect = 6.9, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 368 SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHN-FGIKVTVLEAKDRIGG 419 S+ A ++ + H ++IGAG G+ A +LH+ G+ + D GG Sbjct: 2 SLEASMHMTAQTTHTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGG 54 >5XGV-A nrPDB Length = 462 Score = 29.3 bits (64), Expect = 7.4, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 + +VII G GP GL A +L G+ VLE D Sbjct: 1 SDTVIIAGGGPVGLMLACELGLAGVDTVVLERHD 34 >3CP8-A nrPDB Length = 641 Score = 29.3 bits (64), Expect = 7.9, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 30/60 (50%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 L+P+ H VI++GAG AG AA + G+ ++ + R+ + + GV G+ Sbjct: 14 LVPRGSHMYDVIVVGAGHAGCEAALAVARGGLHCLLITSDLSAVARMSCNPAIGGVAKGQ 73 >2EQ6-A nrPDB Length = 464 Score = 29.3 bits (64), Expect = 8.3, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 +I+IG GP G AA + G+KV +EA + +GG Sbjct: 9 LIVIGTGPGGYHAAIRAAQLGLKVLAVEAGE-VGG 42 >6QVI-A nrPDB Length = 534 Score = 28.9 bits (63), Expect = 8.3, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 18/93 (19%) Query: 399 RQLHNFGIKVTVLEAKDRIGGRVW---DDKSFKGVTVGRGAQIVNGCINNPVALMCEQLG 455 RQ+ + + V K +GG + KGV VGRGAQ + G E +G Sbjct: 203 RQVQDLCASLRVQYGKISVGGSTQIGEPNNKVKGVFVGRGAQDITG----------ENVG 252 Query: 456 ISMHKFGERCDLIQEGGRITD----PTIDKRMD 484 + + G C G ++D PT+D ++D Sbjct: 253 VCRNNKGV-CTEAMGGFDLSDPPPFPTLDAKLD 284 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4FWE-A nrPDB 1340 0.0 2BXR-A nrPDB 455 e-128 1O5W-A nrPDB 453 e-127 2BK5-A nrPDB 422 e-118 3KVE-A nrPDB 370 e-102 1F8S-A nrPDB 364 e-101 1REO-A nrPDB 360 2e-99 3L1R-A nrPDB 346 3e-95 3RHA-A nrPDB 324 1e-88 3BI4-A nrPDB 323 3e-88 6CR0-A nrPDB 313 2e-85 2JB2-A nrPDB 299 5e-81 3ABT-A nrPDB 292 4e-79 5L3D-A nrPDB 288 7e-78 3NK2-X nrPDB 230 1e-60 2VVL-G nrPDB 180 3e-45 5MOG-A nrPDB 123 3e-28 4IV9-A nrPDB 112 6e-25 4DGK-A nrPDB 84 3e-16 1SEZ-A nrPDB 78 1e-14 3LXD-A nrPDB 69 8e-12 3K30-A nrPDB 67 3e-11 Sequences not found previously or not previously below threshold: 2COM-A nrPDB 130 3e-30 2L3D-A nrPDB 128 1e-29 5IT3-A nrPDB 122 6e-28 3X0V-A nrPDB 100 3e-21 3WE0-A nrPDB 99 9e-21 3LOV-A nrPDB 82 1e-15 3I6D-A nrPDB 75 2e-13 4IVM-B nrPDB 71 2e-12 1I8T-A nrPDB 66 1e-10 4RPJ-A nrPDB 61 2e-09 5ZBC-A nrPDB 61 2e-09 5NMX-A nrPDB 61 2e-09 5BR7-A nrPDB 59 6e-09 5VJ7-A nrPDB 59 8e-09 5JFC-L nrPDB 59 8e-09 2UZZ-A nrPDB 58 1e-08 3KYB-A nrPDB 58 2e-08 3UKH-A nrPDB 57 2e-08 5EQD-A nrPDB 57 4e-08 3BHF-A nrPDB 55 1e-07 4MO2-B nrPDB 53 5e-07 4ZCC-A nrPDB 51 2e-06 3KKJ-A nrPDB 51 3e-06 2IVE-A nrPDB 51 3e-06 4UIR-A nrPDB 50 5e-06 2YQU-A nrPDB 49 6e-06 2TMD-A nrPDB 49 6e-06 4YRY-B nrPDB 49 1e-05 2CVJ-A nrPDB 49 1e-05 3MJ4-A nrPDB 49 1e-05 4OVI-A nrPDB 48 1e-05 3UP5-A nrPDB 48 1e-05 4Y4M-A nrPDB 47 2e-05 1NHQ-A nrPDB 47 2e-05 2Q7V-A nrPDB 47 3e-05 4REP-A nrPDB 47 3e-05 4Y4N-A nrPDB 47 3e-05 1ZOV-A nrPDB 47 4e-05 6JDK-A nrPDB 46 5e-05 6N7F-A nrPDB 46 6e-05 3JSK-A nrPDB 46 9e-05 3R9U-A nrPDB 46 1e-04 4X4J-A nrPDB 45 1e-04 5GJK-A nrPDB 45 1e-04 5J5Z-A nrPDB 44 2e-04 5UTH-A nrPDB 44 2e-04 1PS9-A nrPDB 44 2e-04 5TR3-A nrPDB 44 2e-04 2A87-A nrPDB 44 2e-04 4AP1-A nrPDB 44 3e-04 1V59-A nrPDB 43 4e-04 1EBD-A nrPDB 43 4e-04 3FG2-P nrPDB 43 5e-04 4A6N-B nrPDB 43 5e-04 3IHG-A nrPDB 43 5e-04 2QA2-A nrPDB 43 5e-04 1RP0-A nrPDB 43 6e-04 5MJK-A nrPDB 43 7e-04 3LAD-A nrPDB 42 7e-04 5TWC-A nrPDB 42 8e-04 4C5O-A nrPDB 42 8e-04 5ER0-A nrPDB 42 8e-04 2GMH-A nrPDB 42 8e-04 4GCM-A nrPDB 42 0.001 4C3X-A nrPDB 42 0.001 6BRD-A nrPDB 42 0.001 1NAA-A nrPDB 42 0.001 3FPZ-A nrPDB 42 0.001 3URH-A nrPDB 41 0.002 4P9S-A nrPDB 41 0.002 3ATQ-A nrPDB 41 0.002 4B1B-A nrPDB 41 0.002 1DOD-A nrPDB 41 0.002 6ER9-A nrPDB 41 0.002 6BZ0-A nrPDB 41 0.002 5TUK-A nrPDB 41 0.003 1LVL-A nrPDB 41 0.003 4ZN0-A nrPDB 40 0.004 5Z70-A nrPDB 40 0.004 5L46-A nrPDB 40 0.004 2GV8-A nrPDB 40 0.004 3RP7-A nrPDB 40 0.005 1DXL-A nrPDB 40 0.005 4RG3-A nrPDB 40 0.005 6CMZ-A nrPDB 40 0.005 4K2X-A nrPDB 40 0.005 3T14-A nrPDB 40 0.005 5KOX-A nrPDB 40 0.006 5W4C-A nrPDB 40 0.006 4K22-A nrPDB 40 0.006 6J0Z-C nrPDB 39 0.006 2RGJ-A nrPDB 39 0.006 3CP8-A nrPDB 39 0.006 5YGQ-A nrPDB 39 0.007 6BPY-A nrPDB 39 0.007 2R9Z-A nrPDB 39 0.007 5Y77-A nrPDB 39 0.007 4EMJ-A nrPDB 39 0.008 6BZ5-A nrPDB 39 0.009 5TUM-A nrPDB 39 0.010 4TXK-A nrPDB 39 0.010 2BRY-A nrPDB 39 0.010 4N9X-A nrPDB 39 0.012 3COX-A nrPDB 39 0.012 3AB1-A nrPDB 38 0.015 3G5Q-A nrPDB 38 0.018 4JDR-A nrPDB 38 0.018 3ISH-A nrPDB 38 0.018 3LZX-A nrPDB 38 0.020 3DDM-A nrPDB 38 0.021 2DCE-A nrPDB 38 0.021 6DLL-A nrPDB 37 0.023 5XGV-A nrPDB 37 0.024 2GAG-B nrPDB 37 0.024 2VOU-A nrPDB 37 0.030 5UWY-A nrPDB 37 0.032 6C6P-A nrPDB 37 0.032 5VT6-A nrPDB 37 0.033 2E5V-A nrPDB 37 0.036 5XHU-A nrPDB 37 0.037 1ZDL-A nrPDB 37 0.038 1C0L-A nrPDB 37 0.039 5U8W-A nrPDB 37 0.040 5X6R-A nrPDB 37 0.041 3NTA-A nrPDB 37 0.043 3NIX-A nrPDB 37 0.044 6GAR-A nrPDB 37 0.046 2BC1-A nrPDB 37 0.047 5TUF-A nrPDB 37 0.048 3GMC-A nrPDB 36 0.056 3D8X-A nrPDB 36 0.066 6ACQ-A nrPDB 36 0.068 1Q1R-A nrPDB 36 0.069 2EQ6-A nrPDB 36 0.073 4YKF-A nrPDB 36 0.074 1FL2-A nrPDB 36 0.074 2YVG-A nrPDB 36 0.078 6IUM-B nrPDB 36 0.078 4JNQ-A nrPDB 36 0.078 1FOH-A nrPDB 36 0.080 3CGD-A nrPDB 36 0.085 1F6M-A nrPDB 36 0.10 3O0H-A nrPDB 36 0.11 5GSN-A nrPDB 35 0.12 4MOP-A nrPDB 35 0.12 2NVK-X nrPDB 35 0.14 5EZ7-A nrPDB 35 0.14 3ICS-A nrPDB 35 0.14 4NTC-A nrPDB 35 0.15 6A37-A nrPDB 35 0.16 6AON-A nrPDB 35 0.16 2VHY-A nrPDB 35 0.17 4USR-A nrPDB 35 0.18 3L8K-A nrPDB 34 0.19 5ZYN-B nrPDB 34 0.23 1D4E-A nrPDB 34 0.23 2RR4-A nrPDB 34 0.23 6DU7-A nrPDB 34 0.25 5X68-A nrPDB 34 0.27 6BWT-A nrPDB 34 0.30 3QJ4-A nrPDB 34 0.30 3WSV-A nrPDB 34 0.31 3IP1-A nrPDB 34 0.34 1GAL-A nrPDB 34 0.34 1GPJ-A nrPDB 34 0.34 4YNU-A nrPDB 34 0.35 2EEZ-A nrPDB 34 0.41 1KNR-A nrPDB 34 0.41 4U2L-A nrPDB 33 0.44 2CUL-A nrPDB 33 0.48 4CBQ-A nrPDB 33 0.49 5EVY-X nrPDB 33 0.53 3IWA-A nrPDB 33 0.53 6GAS-A nrPDB 33 0.56 4H7U-A nrPDB 33 0.56 2QAE-A nrPDB 33 0.58 3OC4-A nrPDB 33 0.70 4CPD-A nrPDB 32 0.72 3HDH-A nrPDB 32 0.79 1F14-A nrPDB 32 0.79 2WOP-A nrPDB 32 0.82 3SM8-A nrPDB 32 0.92 2ZBW-A nrPDB 32 0.94 2A9F-A nrPDB 32 1.1 1QO8-A nrPDB 32 1.2 2BS2-A nrPDB 32 1.2 2CDU-A nrPDB 32 1.3 5OC1-A nrPDB 32 1.4 4CUK-A nrPDB 32 1.4 4FFM-A nrPDB 31 1.7 3CUK-A nrPDB 31 1.7 1VE9-A nrPDB 31 1.7 2QA1-A nrPDB 31 1.7 1XDI-A nrPDB 31 2.0 5V36-A nrPDB 31 2.3 2HQM-A nrPDB 31 2.4 5YPT-A nrPDB 31 2.4 2JFH-A nrPDB 31 2.5 1VDC-A nrPDB 30 5.7 >4FWE-A nrPDB Length = 796 Score = 1340 bits (3467), Expect = 0.0, Method: Composition-based stats. Identities = 794/796 (99%), Positives = 794/796 (99%) Query: 27 GRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLS 86 G AKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLS Sbjct: 1 GHMAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLS 60 Query: 87 CGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPE 146 CGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPE Sbjct: 61 CGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPE 120 Query: 147 CRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLI 206 CRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLI Sbjct: 121 CRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLI 180 Query: 207 LPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMN 266 LPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMN Sbjct: 181 LPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMN 240 Query: 267 RYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEAL 326 RYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEAL Sbjct: 241 RYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEAL 300 Query: 327 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI 386 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI Sbjct: 301 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI 360 Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP 446 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP Sbjct: 361 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP 420 Query: 447 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD 506 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD Sbjct: 421 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD 480 Query: 507 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA 566 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA Sbjct: 481 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA 540 Query: 567 QFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT 626 QFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT Sbjct: 541 QFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT 600 Query: 627 VPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP 686 VPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP Sbjct: 601 VPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP 660 Query: 687 SASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEV 746 SASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEV Sbjct: 661 SASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEV 720 Query: 747 PDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVT 806 PDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVT Sbjct: 721 PDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVT 780 Query: 807 GAYLSGVREASKIAAF 822 GAYLSGVREASKIAAF Sbjct: 781 GAYLSGVREASKIAAF 796 >2BXR-A nrPDB Length = 527 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 106/460 (23%), Positives = 176/460 (38%), Gaps = 33/460 (7%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVN 440 H V++IG G +GL+AA+ L +G+ V VLEA+DR+GGR + ++ V G V Sbjct: 12 HMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYV- 70 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFN----ALLDVVSE 496 G N + + ++LGI +K L+Q + T R F A LD + Sbjct: 71 GPTQNRILRLSKELGIETYKVNVSERLVQ---YVKGKTYPFRGAFPPVWNPIAYLDYNNL 127 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVL------QFHLSNLEYACGSN 550 WR +++P E + K + EL ++ +F + S Sbjct: 128 WRTIDNMGKEIPTDAPWEAQHAD--KWDKMTMKELIDKICWTKTARRFAYLFVNINVTSE 185 Query: 551 LHQVSAR--SWDHNE-------FFAQFAGDHTLLTPGYSVIIEKLAE--GLDIQLKSPVQ 599 H+VSA W + F G G + E++ + G ++L PV Sbjct: 186 PHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVT 245 Query: 600 CIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGII 659 +D S D + + T + Y + V+ +P L K I F P L ++ + I L G + Sbjct: 246 HVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAK--IHFRPELPAERNQLIQRLPMGAV 303 Query: 660 EKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVA 719 K + + FW K D+ G + + D P +M I Sbjct: 304 IKCMMYYKEAFWKKK----DYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKAD 359 Query: 720 SVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAY 779 + L + ++ ++ QE P Y W + + Y+ G Y Sbjct: 360 RLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQY 419 Query: 780 DIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + G +FFAG T + + GA +G R A ++ Sbjct: 420 GRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREV 459 >1O5W-A nrPDB Length = 534 Score = 453 bits (1165), Expect = e-127, Method: Composition-based stats. Identities = 106/460 (23%), Positives = 178/460 (38%), Gaps = 33/460 (7%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVN 440 H V++IG G +GLAAA+ L + I V VLEA+DR+GGR + ++ V G V Sbjct: 20 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYV- 78 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH--FNAL--LDVVSE 496 G N + + ++LGI +K L+Q + T R F +N L LD + Sbjct: 79 GPTQNRILRLSKELGIETYKVNVNERLVQ---YVKGKTYPFRGAFPPVWNPLAYLDYNNL 135 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVL------QFHLSNLEYACGSN 550 WR +++P+ + + + + +L ++ +F + S Sbjct: 136 WRTMDEMGKEIPVDAPWQA--RHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSE 193 Query: 551 LHQVSAR--SWDHNE-------FFAQFAGDHTLLTPGYSVIIEKLAE--GLDIQLKSPVQ 599 H+VSA W + F G G + E++ G ++L SPV Sbjct: 194 PHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVT 253 Query: 600 CIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGII 659 ID + D + V T + Y + V+ +P L K I F P L ++ + I L G + Sbjct: 254 YIDQTDDNIIVETLNHEHYECKYVISAIPPILTAK--IHFKPELPPERNQLIQRLPMGAV 311 Query: 660 EKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVA 719 K + + FW K D+ G + + + D P +M I Sbjct: 312 IKCMVYYKEAFWKKK----DYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKAD 367 Query: 720 SVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAY 779 + L ++ ++ QE P Y W + + Y+ G Y Sbjct: 368 RLAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQY 427 Query: 780 DIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + G ++FAG T + + GA +G R A ++ Sbjct: 428 GRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREV 467 >2BK5-A nrPDB Length = 520 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 102/451 (22%), Positives = 179/451 (39%), Gaps = 33/451 (7%) Query: 392 PAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMC 451 +G+AAA+ LH+ G+ V VLEA+DR+GGR + ++ K V G V G N + + Sbjct: 14 ISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV-GPTQNRILRLA 72 Query: 452 EQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH--FNA--LLDVVSEWRKDKTQLQDV 507 ++LG+ +K E LI + + R F +N LD + WR +++ Sbjct: 73 KELGLETYKVNEVERLIHH---VKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREI 129 Query: 508 PLGEKIEEIYKAFIKESGIQFSELEGQVL------QFHLSNLEYACGSNLHQVSAR--SW 559 P + + + EL ++ Q + + H+VSA W Sbjct: 130 PSDAPWKAPLAE--EWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLW 187 Query: 560 DHNE-------FFAQFAGDHTLLTPGYSVIIEKLAE--GLDIQLKSPVQCIDYSGDEVQV 610 + F G G + E++ + G ++L+ PV ID + + V V Sbjct: 188 YVKQCGGTTRIFSTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLV 247 Query: 611 TTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRF 670 T + Y A+ V+ +P L K I FNPPL + + I + G + K + + F Sbjct: 248 ETLNHEMYEAKYVISAIPPTLGMK--IHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305 Query: 671 WDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVL 730 W K D+ G + + + D P+ ++ +M I + L ++ L Sbjct: 306 WRKK----DYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERL 361 Query: 731 QQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTV 790 ++ ++ E +P Y W + + Y+ G Y + + Sbjct: 362 KKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRI 421 Query: 791 FFAGEATNRHFPQTVTGAYLSGVREASKIAA 821 +FAG T H+ + GA +G R A +I Sbjct: 422 YFAGTETATHWSGYMEGAVEAGERAAREILH 452 >3KVE-A nrPDB Length = 486 Score = 370 bits (949), Expect = e-102, Method: Composition-based stats. Identities = 101/472 (21%), Positives = 186/472 (39%), Gaps = 46/472 (9%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 L K + K V+++GAG +GL+AA L G KVTVLEA +R GGRV ++ K Sbjct: 27 LKKTSNPKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRNSKEGWYANL 86 Query: 436 AQIVNGCINNPVALMCEQLGISMHKFGERCD--------LIQEGGRITDPTIDKRMDFHF 487 + + V + G+++++F + D + + G + + + Sbjct: 87 GPMRIPEKHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVNKD--PGLLKYPV 144 Query: 488 NALLDVVSEWRKDKTQLQDVPLGEKIEEIYK---AFIKESGIQFSELEGQVLQFHLS-NL 543 SE K QL + LG ++++ + ++I +S E + + +LS Sbjct: 145 KP-----SEEGKSAGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEGNLSPGA 199 Query: 544 EYACGSNLHQVSA------RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLD--IQLK 595 G L++ S S H++ FA + G + + ++ ++ Sbjct: 200 VDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKR-FDEIVGGMDQLPTSMYRAIEEKVKFN 258 Query: 596 SPVQCIDYSGDEVQVTT----TDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAI 651 + V I + ++V VT D + +A V+V ++ IQF PPL KK A+ Sbjct: 259 ARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVCTTSRAARR--IQFEPPLPPKKQHAL 316 Query: 652 NSLGAGIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLM 710 S+ KI L +FW D + G +P F + + + V++ Sbjct: 317 RSVHYRSGTKIFLTCSSKFWEDDGIHGGKSTTDLPSR------FIYYPNHNFSTGVGVII 370 Query: 711 SVIAGEAVASVRTL---DDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAY 767 + G+ + L D ++ ++ + +L KE+ + +WS D + A Sbjct: 371 AYGIGDDANFFQALKFKDCADIVFNDLSLIHQLPKEEIQSFCYPSMIQKWSLDKYAMGAI 430 Query: 768 SFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + + + QG +FFAGE T + SG+ A + Sbjct: 431 TTFTPYQF-QRFSEALTAPQGRIFFAGEYTAEA-HGWIDSTIKSGLTAARDV 480 >1F8S-A nrPDB Length = 498 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 100/472 (21%), Positives = 181/472 (38%), Gaps = 46/472 (9%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 L + K V+I+GAG AGL+AA L G +VTVLEA +R GGRV ++ + Sbjct: 27 LKATSNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANL 86 Query: 436 AQIVNGCINNPVALMCEQLGISMHKFGERCD--------LIQEGGRITDPTIDKRMDFHF 487 + + V + + +++F + D + ++ G + + + Sbjct: 87 GPMRLPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKD--PGLLKYPV 144 Query: 488 NALLDVVSEWRKDKTQLQDVPLGEKIEEIYK---AFIKESGIQFSELEGQVLQFHLS-NL 543 SE K QL + LG+ +EE+ + ++I +S E + + LS Sbjct: 145 KP-----SEAGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLSPGA 199 Query: 544 EYACGSNLHQVSA------RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSP 597 G L++ S S H++ FA + G + + + ++ Sbjct: 200 VDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKR-FDEIVDGMDKLPTAMYRDIQDKVHFN 258 Query: 598 VQCIDYSGDEVQVTTTDGT------GYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAI 651 Q I ++ +VT T +A V+V ++ I+FNPPL KK A+ Sbjct: 259 AQVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCTTSRAVR--LIKFNPPLLPKKAHAL 316 Query: 652 NSLGAGIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLM 710 S+ KI L +FW D + G +P F + + + V++ Sbjct: 317 RSVHYRSGTKIFLTCTTKFWEDDGIHGGKSTTDLPSR------FIYYPNHNFTNGVGVII 370 Query: 711 SVIAGEAVASVRTLDDK---QVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAY 767 + G+ + LD K ++ ++ + +L K+ + +WS D + Sbjct: 371 AYGIGDDANFFQALDFKDCADIVFNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYAMGGI 430 Query: 768 SFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + D + QG ++FAGE T + SG+R A + Sbjct: 431 TTFTPYQFQHFSDPLTAS-QGRIYFAGEYTA-QAHGWIDSTIKSGLRAARDV 480 >1REO-A nrPDB Length = 486 Score = 360 bits (923), Expect = 2e-99, Method: Composition-based stats. Identities = 95/472 (20%), Positives = 181/472 (38%), Gaps = 46/472 (9%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 L + K V+++GAG +GL+AA L G +VTVLEA +R GGRV ++ K Sbjct: 27 LKATSNPKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANL 86 Query: 436 AQIVNGCINNPVALMCEQLGISMHKFGERCD--------LIQEGGRITDPTIDKRMDFHF 487 + + V + G+ +++F + D + + G + + + Sbjct: 87 GPMRLPEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVKKD--PGVLKYPV 144 Query: 488 NALLDVVSEWRKDKTQLQDVPLGEKIEEIYK---AFIKESGIQFSELEGQVLQFHLS-NL 543 SE K QL + LG+ +EE+ + ++I +S E + + +LS Sbjct: 145 KP-----SEEGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGA 199 Query: 544 EYACGSNLHQVSA------RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLD--IQLK 595 G +++ S S H++ FA + G + + ++ + L Sbjct: 200 VDMIGDLMNEDSGYYVSFPESLRHDDIFAYEKR-FDEIVGGMDKLPTSMYRAIEEKVHLN 258 Query: 596 SPVQCIDYSGDEVQVTT----TDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAI 651 + V I + ++V V + +A V+V ++ I+F PPL KK A+ Sbjct: 259 AQVIKIQKNAEKVTVVYQTPAKEMASVTADYVIVCTTSRATRR--IKFEPPLPPKKAHAL 316 Query: 652 NSLGAGIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLM 710 S+ KI L +FW D + G +P F + + + V++ Sbjct: 317 RSVHYRSGTKIFLTCTKKFWEDEGIHGGKSTTDLPSR------FIYYPNHNFTSGVGVII 370 Query: 711 SVIAGEAVASVRTLDDK---QVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAY 767 + G+ + LD K ++ ++ + +L +E+ + +WS D + Sbjct: 371 AYGIGDDANFFQALDFKDCADIVINDLSLIHQLPREEIQTFCYPSMIQKWSLDKYAMGGI 430 Query: 768 SFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + + ++FAGE T + SG+R A + Sbjct: 431 TTFTPYQFQH-FSESLTASVDRIYFAGEHTAEA-HGWIDSTIKSGLRAARDV 480 >3L1R-A nrPDB Length = 478 Score = 346 bits (887), Expect = 3e-95, Method: Composition-based stats. Identities = 132/468 (28%), Positives = 204/468 (43%), Gaps = 57/468 (12%) Query: 384 SVIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV--- 439 VI++GAG +G++AA++L GI + +LEA D IGGR+ +F G+ V GA V Sbjct: 6 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM-HKTNFAGINVELGANWVEGV 64 Query: 440 NGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPT-IDKRMDFHFNALLDVVSEWR 498 NG NP+ + + + F D + + D D+ L D V E Sbjct: 65 NGGKMNPIWPIVNST-LKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEE-- 121 Query: 499 KDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSN--------------LE 544 +GEK+ A ++ S L Q L H N + Sbjct: 122 ----------MGEKLSATLHASGRDD---MSILAMQRLNEHQPNGPATPVDMVVDYYKFD 168 Query: 545 YACGSNLHQVSARSWDHNEFFAQFAGDHTLLTP--GYSVIIEKLAE-------------G 589 Y S ++ F+ F D + GY ++ LA Sbjct: 169 YEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVD 228 Query: 590 LDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMK 649 +QL V+ I YS V V T D + YSA V+V+ L +LQ IQF P L K++ Sbjct: 229 PRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVR 288 Query: 650 AINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKK-HSV 708 AI + I L+FP +FW + +G +FF + ++S+RG + V+ + + Q +V Sbjct: 289 AIYQFDMAVYTMIFLKFPRKFW-PEGKGREFFLY---ASSRRGYYGVWQEFEKQYPDANV 344 Query: 709 LMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYS 768 L+ + E + D+Q + M LR++F ++VPD T V RW +D + + +S Sbjct: 345 LLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFS 404 Query: 769 FVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREA 816 G + YD + G V+F GE T+ H+ V GAYLSG+ A Sbjct: 405 NWPVGVNRYEYDQL-RAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSA 451 >3RHA-A nrPDB Length = 482 Score = 324 bits (829), Expect = 1e-88, Method: Composition-based stats. Identities = 101/464 (21%), Positives = 191/464 (41%), Gaps = 48/464 (10%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 ++ V+I+GAGP+GL AAR+L G+ V VLEA+DR+GGR W D G + G Q V+ Sbjct: 7 DRDVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGRTWTDT-IDGAMLEIGGQWVS- 64 Query: 442 CINNPVALMCEQLGISMH---KFGERCDLIQEGGRI--------TDPTIDKRMDFHFNAL 490 + + ++LG+ M+ + GE + +G R + T MD A+ Sbjct: 65 PDQTVLMELLDELGLKMYSRYRDGESVYIGADGKRTQYTGDTFPVNETTKAEMD-KLVAI 123 Query: 491 LDVVSEWRKDKTQLQDVPLGEKIEEI-YKAFIKESGIQFSELEGQVLQFHLSNLEYACGS 549 LD ++ T+ P +++ I + +++++ + + L A G Sbjct: 124 LDELAA-EIGPTEPWAHPKARELDTISFHHWLRQN-----SNDEEACN--NIGLFIAGGM 175 Query: 550 NLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGL-------------DIQLKS 596 A S A AG + LT ++ +++ G+ D+ L S Sbjct: 176 LTKPAHAFSALQAVLMAASAGSFSHLTDEDFILDKRVIGGMQQVSLLQAAELGDDVVLNS 235 Query: 597 PVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGA 656 PV+ I + + V V + T +A+ V++ VP L + + F+PPL ++ + Sbjct: 236 PVRTIKWDENGVSVVSERAT-VNARFVIMAVPPNLYSR--VSFDPPLPRRQHQMHQHQSL 292 Query: 657 GIIEKIALQFPYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAG 715 G++ K+ + FW + + G F V+ + + L+ ++ Sbjct: 293 GLVIKVHAVYDTPFWREEGLSGTGFSAGALVQE-------VYDNTNHGDSRGTLVGFVSD 345 Query: 716 EAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGS 775 E +V L + + + ++ ++ P Y+ + W ++ W + AY+ G Sbjct: 346 EKADAVFELSAEDRKKAILESIAGFLGDK-ALTPEVYYESDWGSEEWTRGAYASSYDLGG 404 Query: 776 GEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 Y G ++++ Q V GA G A++I Sbjct: 405 LHRYGKDQHANVGPIYWSSSDLAAEGYQHVDGAVRMGQATAARI 448 >3BI4-A nrPDB Length = 516 Score = 323 bits (827), Expect = 3e-88, Method: Composition-based stats. Identities = 125/518 (24%), Positives = 205/518 (39%), Gaps = 102/518 (19%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 K VIIIGAG AGL AA LH GI VLEA+DR+GGR+ ++G GA + Sbjct: 9 KKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHHD 68 Query: 442 CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDK 501 + NP+ L QL ++ G + + I R+D LL++V Sbjct: 69 TLTNPLFLEEAQLSLN---DGRTRFVFDDDNFIYIDEERGRVDHDKELLLEIV------- 118 Query: 502 TQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVL----QFHLSN-----------LEYA 546 D + + E + + S F +L + L QF ++ LE Sbjct: 119 ----DNEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELW 174 Query: 547 CGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLD---IQLKSPVQCIDY 603 G + +SA+ + +F + L Y +++++A+ ++L V+ I Sbjct: 175 HGLDWKLLSAK----DTYFGHQGRNAFALN--YDSVVQRIAQSFPQNWLKLSCEVKSITR 228 Query: 604 S-GDEVQVTTTDGTGYSAQKVLVTVPLALLQ---------KGAIQFNPPLSEKKMKAINS 653 V V DGT Y+A V++TVP ++L +G I+F PPL A + Sbjct: 229 EPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLKPVIQDAFDK 288 Query: 654 LGAGIIEKIALQFPYRFWDSKV--------QGADFFGHVPPSASKRGLFAVFYDMDPQKK 705 + G + K+ +F W ++ +F V + + L ++ D QK Sbjct: 289 IHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSMLEREDSQKH 348 Query: 706 HSV--------LMSVIAGEAVASVRTL-------------DDKQVL----QQCMATLREL 740 SV +++ VAS L +DK+ L Q + + + Sbjct: 349 TSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMKC 408 Query: 741 FKEQEVPDPTK---------------YFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAED 785 ++V D + V+ W+ DP+ + AYS G + D++ Sbjct: 409 LDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPG--DDPVDMVVAM 466 Query: 786 IQG---TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 820 G + FAGE T GA+ SG REA++I+ Sbjct: 467 SNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREATRIS 504 >6CR0-A nrPDB Length = 440 Score = 313 bits (801), Expect = 2e-85, Method: Composition-based stats. Identities = 97/468 (20%), Positives = 181/468 (38%), Gaps = 71/468 (15%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 I++GAG +GL AAR+L G V ++EA+ R+GGR +F G V G V+ C Sbjct: 10 DAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRT-HVVNFLGRPVEIGGAGVHWCQ 68 Query: 444 NNPVALMCEQLGISMHKFGERCDL------IQEGGRITDP--TIDKRMDFHFNALLDVVS 495 + A M ++ G K DL +G +I P T D+ F Sbjct: 69 PHVFAEM-QRYGFGF-KEAPLADLDKAYMVFADGQKIDVPPATFDEEYTTAFEKFCSRSR 126 Query: 496 EW---------RKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFH---LSNL 543 E + + L V + +E + + +Q + + ++ + + L Sbjct: 127 ELFPRPYSPLDNHEVSNLDGVSARDHLESL-----GLNELQLASMNAELTLYGGAPTTEL 181 Query: 544 EYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEG--LDIQLKSPVQCI 601 Y H ++ SWD F H + G + + + + + D + PV+ + Sbjct: 182 SYPSFVKFHALA--SWDTITFTDSEKRYH--VQGGTNALCQAIFDDCRADSEFGVPVEAV 237 Query: 602 DYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEK 661 + + V VT D + A ++T+P + ++F PPL +K I Sbjct: 238 AQTDNGVTVTLADKRVFRALTCVLTLPTKVYAD--VRFEPPLPPEKRAFIEHAEMA---- 291 Query: 662 IALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASV 721 GA+ + HV ++ L F D + + + + + ++ Sbjct: 292 --------------DGAELYVHV-----RQNLGNTFTFCDDPNPFNAVQTYAYDDELGTI 332 Query: 722 -------RTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGG 774 ++L + + A +R++ + EV + Y W+ D + + +Y ++ G Sbjct: 333 LKITIGRQSLINLENFDAIAAEIRKIHGDVEVLEALPY---NWAMDEYARTSYPAMRKGW 389 Query: 775 SGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF 822 D+ + +FFAG AT + + + GA SG+R +I F Sbjct: 390 FSRYKDMAK--PENRLFFAGSATADGWHEYIDGAIESGIRVGREIRHF 435 >2JB2-A nrPDB Length = 489 Score = 299 bits (764), Expect = 5e-81, Method: Composition-based stats. Identities = 104/497 (20%), Positives = 183/497 (36%), Gaps = 71/497 (14%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS-------- 426 L+ K + SV+++G GPAGL +A +L G KVTVLEA+ R GGRVW + Sbjct: 4 LIGKVKGSHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGRVWTARGGSEETDLS 63 Query: 427 --FKGVTVGRGAQIVNGCINNPVAL----MCEQLGISMHKFGERC---------DLIQEG 471 + T G G P + C +LG+ + FG + D G Sbjct: 64 GETQKCTFSEGHFYNVGATRIPQSHITLDYCRELGVEIQGFGNQNANTFVNYQSDTSLSG 123 Query: 472 GRITDPTIDKRMDFHFNALLDVVSEW--------RKDKTQLQDV--PLGEKIEEIYKAFI 521 +T + + LL ++ R+DK L + G+ ++ ++ Sbjct: 124 QSVTYRAAKADTFGYMSELLKKATDQGALDQVLSREDKDALSEFLSDFGDLSDD--GRYL 181 Query: 522 KESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLL----TP 577 S + G L F +A Q RS F F D ++ Sbjct: 182 GSSRRGYDSEPGAGLNFGTEKKPFAM-----QEVIRSGIGRNFSFDFGYDQAMMMFTPVG 236 Query: 578 GYSVIIEKLAEGL---DIQLKSPVQCIDYSGDEVQVTTTDG---TGYSAQKVLVTVPLAL 631 G I + + +I + V + + V V T G +A + T+P L Sbjct: 237 GMDRIYYAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTIPPHL 296 Query: 632 LQKGAIQFNPP---LSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSA 688 + G +Q N P L+ K +S G K+ +++ R+W+++ + +G + Sbjct: 297 V--GRLQNNLPGDVLTALKAAKPSSSG-----KLGIEYSRRWWETEDR---IYGGASNTD 346 Query: 689 SKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPD 748 YD + V+ +G+ + +L +Q L + +A E+ E+ D Sbjct: 347 KDISQIMFPYDHYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEGSEIHGEKYTRD 406 Query: 749 PTKYFVTRWSTDPWIQMAYSFVKTGGSGE------AYDIIAEDIQGTVFFAGEATNRHFP 802 + F W + + A++ G Y+ + E ++FAG+ + + Sbjct: 407 ISSSFSGSWRRTKYSESAWANWAGSGGSHGGAATPEYEKLLE-PVDKIYFAGDHLS-NAI 464 Query: 803 QTVTGAYLSGVREASKI 819 GA S + I Sbjct: 465 AWQHGALTSARDVVTHI 481 >3ABT-A nrPDB Length = 662 Score = 292 bits (747), Expect = 4e-79, Method: Composition-based stats. Identities = 141/452 (31%), Positives = 218/452 (48%), Gaps = 37/452 (8%) Query: 395 LAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQL 454 L A L + VL K G+ + + QI + ++L Sbjct: 215 LEATSYLS-HQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKEL 273 Query: 455 GISM----HKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVP-- 508 M K E +E + P D +F + ++ K+ +L + Sbjct: 274 LNKMVNLKEKIKELHQQYKEASEVKPP-RDITAEFLVKSKHRDLTALCKEYDELAETQGK 332 Query: 509 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 568 L EK++E+ S + S + Q+L +H +NLE+A + L +S + WD ++ F +F Sbjct: 333 LEEKLQELEAN--PPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDF-EF 389 Query: 569 AGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY--SGDEVQVTTTDGTG----YSAQK 622 G H + GYS + LAEGLDI+L + V+ + Y SG EV T T Y Sbjct: 390 TGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDA 449 Query: 623 VLVTVPLALL--QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 680 VL T+PL +L Q A+QF PPL E K A+ +G G + K+ L F FWD V + Sbjct: 450 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSV---NL 506 Query: 681 FGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLREL 740 FGHV + + RG +F+++ K +L++++AGEA + + D ++ +C+A L+ + Sbjct: 507 FGHVGSTTASRGELFLFWNLY---KAPILLALVAGEAAGIMENISDDVIVGRCLAILKGI 563 Query: 741 FKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAED------------IQG 788 F VP P + V+RW DPW + +YS+V G SG YD++A+ Sbjct: 564 FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIP 623 Query: 789 TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 820 +FFAGE T R++P TV GA LSG+REA +IA Sbjct: 624 RLFFAGEHTIRNYPATVHGALLSGLREAGRIA 655 Score = 238 bits (607), Expect = 7e-63, Method: Composition-based stats. Identities = 83/273 (30%), Positives = 131/273 (47%), Gaps = 21/273 (7%) Query: 287 DVMELDELYEFPEYSRDPT----MYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 15 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 72 Query: 343 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLH 402 V V R+ ++ R GLIN G+ LP K VIIIG+G +GLAAARQL Sbjct: 73 SDTVL-VHRVHSYLERHGLINFGIYKRIKP---LPTKKTGK-VIIIGSGVSGLAAARQLQ 127 Query: 403 NFGIKVTVLEAKDRIGGRVWDDKSFKGVTV-GRGAQIVNGCINNPVALMCEQLGISMHKF 461 +FG+ VT+LEA+DR+GGRV + KG V GA +V G NP+A++ +Q+ + + K Sbjct: 128 SFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKI 185 Query: 462 GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS--EWRKDKTQLQDVPLG-----EKIE 514 ++C L + G+ D+ ++ FN LL+ S + D L + P+ E + Sbjct: 186 KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVI 245 Query: 515 EIYKAFIKESGIQFSELEGQVLQFHLSNLEYAC 547 ++ + +K+ I+ + + + L Sbjct: 246 QLQEKHVKDEQIEHWKKIVKTQEELKELLNKMV 278 >5L3D-A nrPDB Length = 852 Score = 288 bits (737), Expect = 7e-78, Method: Composition-based stats. Identities = 140/452 (30%), Positives = 218/452 (48%), Gaps = 37/452 (8%) Query: 395 LAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQL 454 L A L + VL K G+ + + QI + ++L Sbjct: 386 LEATSYLS-HQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKEL 444 Query: 455 GISM----HKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVP-- 508 M K E +E + P D +F + ++ K+ +L + Sbjct: 445 LNKMVNLKEKIKELHQQYKEASEVKPP-RDITAEFLVKSKHRDLTALCKEYDELAETQGK 503 Query: 509 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 568 L EK++E+ S + S + Q+L +H +NLE+A + L +S + WD ++ F +F Sbjct: 504 LEEKLQELEAN--PPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDF-EF 560 Query: 569 AGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY--SGDEVQVTTTDGTG----YSAQK 622 G H + GYS + LAEGLDI+L + V+ + Y SG EV T T Y Sbjct: 561 TGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDA 620 Query: 623 VLVTVPLALL--QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 680 VL T+PL +L Q A+QF PPL E K A+ +G G + K+ L F FWD V + Sbjct: 621 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSV---NL 677 Query: 681 FGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLREL 740 FGHV + + RG +F+++ K +L++++AGEA + + D ++ +C+A L+ + Sbjct: 678 FGHVGSTTASRGELFLFWNLY---KAPILLALVAGEAAGIMENISDDVIVGRCLAILKGI 734 Query: 741 FKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAED------------IQG 788 F VP P + V+RW DPW + ++S+V G SG YD++A+ Sbjct: 735 FGSSAVPQPKETVVSRWRADPWARGSHSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIP 794 Query: 789 TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 820 +FFAGE T R++P TV GA LSG+REA +IA Sbjct: 795 RLFFAGEHTIRNYPATVHGALLSGLREAGRIA 826 Score = 237 bits (605), Expect = 1e-62, Method: Composition-based stats. Identities = 83/273 (30%), Positives = 131/273 (47%), Gaps = 21/273 (7%) Query: 287 DVMELDELYEFPEYSRDPT----MYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 186 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 243 Query: 343 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLH 402 V V R+ ++ R GLIN G+ LP K VIIIG+G +GLAAARQL Sbjct: 244 SDTVL-VHRVHSYLERHGLINFGIYKRIKP---LPTKKTGK-VIIIGSGVSGLAAARQLQ 298 Query: 403 NFGIKVTVLEAKDRIGGRVWDDKSFKGVTV-GRGAQIVNGCINNPVALMCEQLGISMHKF 461 +FG+ VT+LEA+DR+GGRV + KG V GA +V G NP+A++ +Q+ + + K Sbjct: 299 SFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKI 356 Query: 462 GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS--EWRKDKTQLQDVPLG-----EKIE 514 ++C L + G+ D+ ++ FN LL+ S + D L + P+ E + Sbjct: 357 KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVI 416 Query: 515 EIYKAFIKESGIQFSELEGQVLQFHLSNLEYAC 547 ++ + +K+ I+ + + + L Sbjct: 417 QLQEKHVKDEQIEHWKKIVKTQEELKELLNKMV 449 >3NK2-X nrPDB Length = 431 Score = 230 bits (587), Expect = 1e-60, Method: Composition-based stats. Identities = 98/464 (21%), Positives = 171/464 (36%), Gaps = 68/464 (14%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW--DDKSFKGVTVGRGAQIV 439 I++G G +GL AAR L N G KV +LE +R+GGR + + ++ G+ V G + Sbjct: 1 MYDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYL 60 Query: 440 NGCINNPVALMCEQLGISM----------HKFGERC------DLIQEGGRITDPTIDKRM 483 + + +A ++ GI H+ G E + T Sbjct: 61 HRKHHPRLAAELDRYGIPTAAASEFTSFRHRLGPTAVDQAFPIPGSEAVAVEAATYTLLR 120 Query: 484 DFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNL 543 D H +D+ + D+PL E ++++ +L QF L+ Sbjct: 121 DAH---RIDLEKGLENQDLEDLDIPLNEYVDKL-------------DLPPVSRQFLLAWA 164 Query: 544 EYACGSNLHQVSAR------SWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGL-DIQLKS 596 G Q SA + H + + G + +++ +++ + +I+L++ Sbjct: 165 WNMLGQPADQASALWMLQLVAAHHYSILGVVLSLDEVFSNGSADLVDAMSQEIPEIRLQT 224 Query: 597 PVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGA 656 V ID SGD V VT DG + A V+V P+ ++ I F P L E++ I Sbjct: 225 VVTGIDQSGDVVNVTVKDGHAFQAHSVIVATPMNTWRR--IVFTPALPERRRSVIEEGHG 282 Query: 657 GIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYD-MDPQKKHSVLMSVIAG 715 G KI + V+GA+ G+F YD + + +L++ Sbjct: 283 GQGLKILIH---------VRGAE----AGIECVGDGIFPTLYDYCEVSESERLLVAF--- 326 Query: 716 EAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGS 775 S D V + L E+ + W DP + + + G Sbjct: 327 TDSGSFDPTDIGAVKDAVLYYLPEV-------EVLGIDYHDWIADPLFEGPWVAPRVGQF 379 Query: 776 GEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + + E G + F G + FP + GA + + I Sbjct: 380 SRVHKELGE-PAGRIHFVGSDVSLEFPGYIEGALETAECAVNAI 422 >2VVL-G nrPDB Length = 495 Score = 180 bits (456), Expect = 3e-45, Method: Composition-based stats. Identities = 93/490 (18%), Positives = 163/490 (33%), Gaps = 54/490 (11%) Query: 359 KGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIG 418 +G+ + GV+S + KD VI+IG G GL A R L G K +LEA+DRIG Sbjct: 17 QGVTSLGVISPPTNIEDTDKD-GPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIG 75 Query: 419 GRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCE-------QLGISMHKFGERCDLIQEG 471 GR W + G G V+ ++ + + + L Sbjct: 76 GRSWS-SNIDGYPYEMGGTWVHWHQSHVWREITRYKMHNALSPSFNFSRGVNHFQLRTNP 134 Query: 472 GRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSEL 531 T T + + +AL + + + P ++ + + +SE Sbjct: 135 TTSTYMTHEAEDELLRSALHKFTNVDGTNGRTVLPFPHDMFYVPEFRKY---DEMSYSER 191 Query: 532 EGQVLQFHLSN--------LEYACGSNLHQVS---ARSWDHNEFFAQFAGDH----TLLT 576 Q+ N + G L S W + Sbjct: 192 IDQIRDELSLNERSSLEAFILLCSGGTLENSSFGEFLHWWAMSGYTYQGCMDCLMSYKFK 251 Query: 577 PGYSVIIEKLAE------GLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLA 630 G S + E L PV+ + D +VT DG + A++V+ T+PL Sbjct: 252 DGQSAFARRFWEEAAGTGRLGYVFGCPVRSVVNERDAARVTARDGREFVAKRVVCTIPLN 311 Query: 631 LLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASK 690 +L IQF+P LS +++ A+ + + K+ + + + G P Sbjct: 312 VLS--TIQFSPALSTERISAMQAGHVSMCTKVHAEVDNK------DMRSWTGIAYPFNKL 363 Query: 691 RGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDD-KQVLQQCMATLRELFKEQEVPDP 749 +A+ P ++ G ++ +D ++ L+ F + + Sbjct: 364 --CYAIGDGTTPAGNTHLV---CFGTDANHIQPDEDVRETLKAVGQLAPGTFGVKRLVF- 417 Query: 750 TKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAY 809 W D + + A+ F + G E + G V FA + + GA Sbjct: 418 -----HNWVKDEFAKGAWFFSRPGMVSECL-QGLREKHGGVVFANSDWALGWRSFIDGAI 471 Query: 810 LSGVREASKI 819 G R A + Sbjct: 472 EEGTRAARVV 481 >2COM-A nrPDB Length = 124 Score = 130 bits (326), Expect = 3e-30, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 17/111 (15%) Query: 287 DVMELDELYEFPEYSRDPT----MYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 25 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 82 Query: 343 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPA 393 V V R+ ++ R GLIN G+ LP G+GP+ Sbjct: 83 SDTVL-VHRVHSYLERHGLINFGIYKRIKP---LPTKKT-------GSGPS 122 >2L3D-A nrPDB Length = 102 Score = 128 bits (321), Expect = 1e-29, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 7/90 (7%) Query: 287 DVMELDELYEFPEYSRDPT----MYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 15 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 72 Query: 343 IRCVQEVERILYFMTRKGLINTGVLSVGAD 372 V V R+ ++ R GLIN G+ Sbjct: 73 SDTVL-VHRVHSYLERHGLINFGIYKRIKP 101 >5MOG-A nrPDB Length = 497 Score = 123 bits (309), Expect = 3e-28, Method: Composition-based stats. Identities = 83/470 (17%), Positives = 161/470 (34%), Gaps = 54/470 (11%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 V+I GAG AGL+ A+ L + G K +LEA+D +GG++ K G G I G Sbjct: 19 QVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGAY 78 Query: 444 NNPVALMCEQLGISMH-KFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEW---RK 499 N L +LGI+ ++ E + + P R DF + W R Sbjct: 79 PNIQNLFG-ELGINDRLQWKEHSMIFAMPNK---PGEFSRFDFPETLPAPLNGIWAILRN 134 Query: 500 DKTQLQDVPLGEKIEEIYKAFIKESG----IQFSELEGQVLQFHLSNLEYAC-------- 547 ++ + + + ++ F+ E Q + Sbjct: 135 NEMLTWPEKVKFALGLLPAMVGGQAYVEAQDGFTVSEWMKKQGVPDRVNDEVFIAMSKAL 194 Query: 548 -GSNLHQVSAR--SWDHNEFFAQFAGDHTLLTPGY--SVIIEKLAE-----GLDIQLKSP 597 N ++S + N F + G G + + + G +++L S Sbjct: 195 NFINPDELSMQCILIALNRFLQEKHGSKMAFLDGNPPERLCMPIVDHVRSLGGEVRLNSR 254 Query: 598 VQCIDYSGDEVQVT---TTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKM----KA 650 +Q I+ + D V TDGT + + P+ +L+ Q E K K Sbjct: 255 IQKIELNPDG-TVKHFALTDGTQITGDAYVFATPVDILKLLVPQ------EWKEISYFKK 307 Query: 651 INSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLM 710 + L + + + F + ++ + + + + + + + Sbjct: 308 LEKLVGVPVINVHIWFDRKLKNTYDHLLFSRSSLLSVYADMSV--TCKEYYDPNRSMLEL 365 Query: 711 SVIAGEA-VASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSF 769 E V D ++++ M L +LF ++ D +K + ++ + Y Sbjct: 366 VFAPAEEWVGR----SDTEIIEATMQELAKLFPDEIAADQSKAKILKYHVVKTPRSVYKT 421 Query: 770 VKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 + E + + AG+ T + + ++ GA LSG A + Sbjct: 422 IPD---CEPCRPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQSV 468 >5IT3-A nrPDB Length = 85 Score = 122 bits (306), Expect = 6e-28, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 7/85 (8%) Query: 287 DVMELDELYEFPEYSRDPT----MYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 342 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 4 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 61 Query: 343 IRCVQEVERILYFMTRKGLINTGVL 367 V V R+ ++ R GLIN G+ Sbjct: 62 SDTVL-VHRVHSYLERHGLINFGIY 85 >4IV9-A nrPDB Length = 557 Score = 112 bits (280), Expect = 6e-25, Method: Composition-based stats. Identities = 86/497 (17%), Positives = 151/497 (30%), Gaps = 69/497 (13%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVL-EAKDRIGGRVWDDK--SFKGVTVGRGAQIVN 440 V I+GAG +GL AA +L G+K VL E++DRIGGRVW + + + Sbjct: 40 RVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRF 99 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTID-KRMDFHFNALLDVVSEWRK 499 + ++ GIS ++ V W+ Sbjct: 100 PPSATGLFHYLKKFGISTSTTFPDPGVVDTELHYRGKRYHWPAGKKPPELFRRVYEGWQS 159 Query: 500 DKTQLQDVPLGEKIEEIYKAFIKESG------IQFSELEGQVLQFHLSNLEYACGSNLHQ 553 ++ + G + + + +SG I + N + H Sbjct: 160 LLSEGYLLEGGSLVAPLDITAMLKSGRLEEAAIAWQGWLNVFRDCSFYNAIVCIFTGRHP 219 Query: 554 VSARSWDHNEFFAQFA-----------------------------GDHTLLTPGYSVIIE 584 W E F F D L+ G S + Sbjct: 220 PGGDRWARPEDFELFGSLGIGSGGFLPVFQAGFTEILRMVINGYQSDQRLIPDGISSLAA 279 Query: 585 KLAEGL-------DIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQ--KG 635 +LA+ D S V I +++ + T G +V+VT +Q Sbjct: 280 RLADQSFDGKALRDRVCFSRVGRISREAEKIIIQTEAGEQRVFDRVIVTSSNRAMQMIHC 339 Query: 636 AIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFA 695 LS +A+ K+ + +FW + RG++ Sbjct: 340 LTDSESFLSRDVARAVRETHLTGSSKLFILTRTKFWIK----NKLPTTIQSDGLVRGVYC 395 Query: 696 V-FYDMDPQKKHSVLMSVIAGEAVASVRTLDDK----QVLQQCMATLRELFKEQEVPDPT 750 + + +P+ VL+S + + + DK QVL +A + F +P Sbjct: 396 LDYQPDEPEGHGVVLLSYTWEDDAQKMLAMPDKKTRCQVLVDDLAAIHPTFASYLLPVDG 455 Query: 751 KYFV----TRWSTDPWIQMAYSFVKTG----GSGEAYDIIAEDIQGT---VFFAGEATNR 799 Y W TDP A+ G + + + ++ AG + + Sbjct: 456 DYERYVLHHDWLTDPHSAGAFKLNYPGEDVYSQRLFFQPMTANSPNKDTGLYLAGCSCSF 515 Query: 800 HFPQTVTGAYLSGVREA 816 + GA + + A Sbjct: 516 AG-GWIEGAVQTALNSA 531 >3X0V-A nrPDB Length = 541 Score = 100 bits (248), Expect = 3e-21, Method: Composition-based stats. Identities = 85/489 (17%), Positives = 165/489 (33%), Gaps = 59/489 (12%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVT---VLEAKDRIGGRVW--DDKSFKGV 430 ++ + V I+GAG +GL A L + I + E+ R GGR++ K Sbjct: 1 AEEELPPRKVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFTDAKHD 60 Query: 431 TVGRGAQ-IVNGCINNPVALMCEQLGISMHKF---GERCDLIQEGGR----ITDPTIDKR 482 GA + + ++ G+ + K+ GE + + DP + Sbjct: 61 YYDIGAMRYPDIPSMKRTFNLFKRTGMPLIKYYLDGENTPQLYNNHFFAKGVVDPYMVSV 120 Query: 483 MDFHFNA--LLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSE---------L 531 + ++D V E + L E ++ + + + E Sbjct: 121 ANGGTVPDDVVDSVGEKLQQAFGYYKEKLAEDFDKGFDELMLVDDMTTREYLKRGGPKGE 180 Query: 532 EGQVLQFHLSNLEYACG--SNLHQVSARSWDHNEFFAQFAGDH-TLLTPGYSVIIEKLAE 588 + F + +E + Q + S + F + G S++++ + E Sbjct: 181 APKYDFFAIQWMETQNTGTNLFDQAFSESVIDSFDFDNPTKPEWYCIEGGTSLLVDAMKE 240 Query: 589 GL--DIQLKSPVQCIDYSGDE-------VQVTTTDGTGYSAQKVLVTVPLALLQKGAIQF 639 L +Q V+ I D V++ D +GYS V T L L + ++ Sbjct: 241 TLVHKVQNNKRVEAISIDLDAPDDGNMSVKIGGKDYSGYS--TVFNTTALGCLDRMDLR- 297 Query: 640 NPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSA-SKRGLFAVFY 698 L + AI L K+AL+F Y +W G + R Y Sbjct: 298 GLNLHPTQADAIRCLHYDNSTKVALKFSYPWWIK--DCGITCGGAASTDLPLRTCVYPSY 355 Query: 699 DMDPQKKHSVLMSVIAGEAVASVRTLDD---------KQVLQQCMATLRELFKE----QE 745 ++ + +L S + + +L ++++ + L L E ++ Sbjct: 356 NLGDTGEAVLLASYTWSQDATRIGSLVKDAPPQPPKEDELVELILQNLARLHAEHMTYEK 415 Query: 746 VPDPT--KYFVTRWSTDPWIQMAYSFVKTGGSGEAYD-IIAEDIQGTVFFAGEATNRHFP 802 + + Y W+ DP + A++ G Y ++ G GEA++ H Sbjct: 416 IKEAYTGVYHAYCWANDPNVGGAFALFGPGQFSNLYPYLMRPAAGGKFHIVGEASSVH-H 474 Query: 803 QTVTGAYLS 811 + G+ S Sbjct: 475 AWIIGSLES 483 >3WE0-A nrPDB Length = 580 Score = 98.7 bits (244), Expect = 9e-21, Method: Composition-based stats. Identities = 86/505 (17%), Positives = 161/505 (31%), Gaps = 81/505 (16%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV--WDDKSFKGVTVG 433 +P H + V I+GAG AGL AA +L G+K V EA ++GGR+ G+ Sbjct: 59 IPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEAS-KMGGRLRSQAFNGTDGIIAE 117 Query: 434 RGAQIVNGCINNPVALMCEQLGISMHKF------GERCDLIQEGGRITD-------PTID 480 G + + ++LG+ F R +I G+ P + Sbjct: 118 LGG-MRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALF 176 Query: 481 KRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHL 540 + + + L+ + + + ++D + E F + F Sbjct: 177 QEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAF-- 234 Query: 541 SNLEYACGSNLHQVSARSWDHNEFF-----------AQFAGDHTL-LTPGYSVIIEKLAE 588 + L + QV + + F DH + G + + + Sbjct: 235 AKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWR 294 Query: 589 GLDIQL--------------KSP---VQCIDYSGDE---VQVTTTDGTGYSAQKVLVTVP 628 + + +P V+ I + D V D Y+A ++T Sbjct: 295 HVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAA---VLTTC 351 Query: 629 LALLQKGAIQFNPPLSEKKM-KAINSLGAGIIEKIALQFPYRFWDSKV--QGADFFGHVP 685 + L I L +KM A++ K + FW K G D Sbjct: 352 QSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTL 411 Query: 686 PSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDD--KQVLQQCMATLRELFKE 743 RG Y D ++ + +++ L ++ +Q + L++++ + Sbjct: 412 TDRLTRGT----YLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPK 467 Query: 744 QEVP-----DPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGT-------VF 791 ++ DP W DP A+ G + A +Q +F Sbjct: 468 TDIAGHIIGDPITI---SWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIF 524 Query: 792 FAGEATNRHF-PQTVTGAYLSGVRE 815 AG+ + + P V GA + + Sbjct: 525 IAGDDVS--WTPAWVEGAVQTSLNA 547 >4DGK-A nrPDB Length = 501 Score = 84.1 bits (206), Expect = 3e-16, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 100/277 (36%), Gaps = 42/277 (15%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 K +IGAG GLA A +L GI V +LE +D+ GGR + + +G T G ++ Sbjct: 1 MKPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYED-QGFTFDAGPTVITD 59 Query: 442 C--INNPVALMCEQL-------------------GISMHKFGERCDLIQEGGRITDP--- 477 I AL +QL G + ++ L + + Sbjct: 60 PSAIEELFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNPRDVE 119 Query: 478 TIDKRMDFHFNALLDVVSEWRKDK-----TQLQDVPLGEKIEEIYKAFIKESGIQFSELE 532 + +D+ + + L+ P K++ + K + S +E Sbjct: 120 GYRQFLDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVA----SYIE 175 Query: 533 GQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAE---- 588 + L+ S G N S+ + ++ G +++ + + Sbjct: 176 DEHLRQAFSFHSLLVGGNPFATSSIYTLIHALEREWG--VWFPRGGTGALVQGMIKLFQD 233 Query: 589 -GLDIQLKSPVQCIDYSGDEVQ-VTTTDGTGYSAQKV 623 G ++ L + V ++ +G++++ V DG + Q V Sbjct: 234 LGGEVVLNARVSHMETTGNKIEAVHLEDGRRFLTQAV 270 >3LOV-A nrPDB Length = 475 Score = 81.8 bits (200), Expect = 1e-15, Method: Composition-based stats. Identities = 79/418 (18%), Positives = 148/418 (35%), Gaps = 59/418 (14%) Query: 382 NKSVIIIGAGPAGLAAARQLHNF--GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 +K ++I+G G GLAAA + +T+LEA +R+GG+V + G T+ RG Sbjct: 4 SKRLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYR-EDGFTIERGPDSY 62 Query: 440 NGCINNPVALMCEQLGIS---MHKFGERCDLIQEGGRITDP-----TIDKRMDFHFNALL 491 + + + E +G+ + + ++ GG P I +D L Sbjct: 63 V-ARKHILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLDLFRQTTL 121 Query: 492 DVVSEWRKDKTQL-----------QDVPLGEKIEEIYKAFIKESGI-------------- 526 E ++ L QD+PLGE + + E I Sbjct: 122 LTEEEKQEVADLLLHPSDSLRIPEQDIPLGEYLRPRLGDALVEKLIEPLLSGIYAGNIDQ 181 Query: 527 --QFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIE 584 F+ V + + + + + + + G L G +IE Sbjct: 182 MSTFATYPQFVANEQKAGSLFEGMRLMRPLD-QLPQTPQTTIKATGQFLSLETGLESLIE 240 Query: 585 KLAEGL---DIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNP 641 +L E L +I+L++P+ I ++ T G Y A VL+T+P +Q P Sbjct: 241 RLEEVLERSEIRLETPLLAISREDGRYRLKTDHGPEY-ADYVLLTIP----HPQVVQLLP 295 Query: 642 P--LSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYD 699 L E + + + + I Q ++G F + S A+ Sbjct: 296 DAHLPELEQ--LTTHSTATVTMIFDQQQSL----PIEGTGFVVNRRAPYSITACTAIDQK 349 Query: 700 MDPQ-KKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTR 756 + H+VL + + + D+ + Q + L ++ +P + ++R Sbjct: 350 WNHSAPDHTVLRAFVGRPGNDHLVHESDEVLQQAVLQDLEKICGR--TLEPKQVIISR 405 >1SEZ-A nrPDB Length = 504 Score = 78.3 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 87/510 (17%), Positives = 165/510 (32%), Gaps = 97/510 (19%) Query: 376 LPKDYHN--KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVG 433 +D H+ K V +IGAG +GLAAA +L G+ VTV EA+ + GG++ S G+ Sbjct: 5 AGEDKHSSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSV-SQDGLIWD 63 Query: 434 RGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDV 493 GA + + L+ + LG+ + ++ L Q I + + L+ Sbjct: 64 EGANTMTESEGDVTFLI-DSLGL---REKQQFPLSQNKRYIARNGTPVLLPSNPIDLIKS 119 Query: 494 VSEWRKDKTQLQDVPL---GEKIEEIYKAFIKESGIQFSELEGQVLQFHL-SNLEYACGS 549 K Q+ P+ +K+ ++ + SG +V+ + + + CG Sbjct: 120 NFLSTGSKLQMLLEPILWKNKKLSQVSDSHESVSGFFQRHFGKEVVDYLIDPFVAGTCGG 179 Query: 550 NLHQVSA-----RSWDHNEFFAQF----------------------------AGDHTLLT 576 + +S W+ + F Sbjct: 180 DPDSLSMHHSFPELWNLEKRFGSVILGAIRSKLSPKNEKKQGPPKTSANKKRQRGSFSFL 239 Query: 577 PGYSVIIEKLAEG---LDIQLKSPVQCI-----------DYSGDEVQVTTTDGTGYSAQK 622 G + + + + +++L S V + +S S Sbjct: 240 GGMQTLTDAICKDLREDELRLNSRVLELSCSCTEDSAIDSWSIISASPHKRQSEEESFDA 299 Query: 623 VLVTVPLALLQKGAI--QFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 680 V++T PL ++ I + NP L I + + + F ++G F Sbjct: 300 VIMTAPLCDVKSMKIAKRGNPFLL----NFIPEVDYVPLSVVITTFKRENVKYPLEG--F 353 Query: 681 FGHVPPSASKRGL--------FAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQ 732 VP + GL +F D P + + + + G + ++ + Sbjct: 354 GVLVPSKEQQHGLKTLGTLFSSMMFPDRAPNNVY-LYTTFVGGSRNRELAKASRTELKEI 412 Query: 733 CMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQ----- 787 + L++L + P ++ Y G YD + + I Sbjct: 413 VTSDLKQLLGAEGEPT-------------YVNHLYWSKAFPLYGHNYDSVLDAIDKMEKN 459 Query: 788 -GTVFFAGEATNRHFPQTVTGAYLSGVREA 816 +F+AG +V A SG A Sbjct: 460 LPGLFYAGNH---RGGLSVGKALSSGCNAA 486 >3I6D-A nrPDB Length = 470 Score = 74.8 bits (182), Expect = 2e-13, Method: Composition-based stats. Identities = 83/477 (17%), Positives = 158/477 (33%), Gaps = 76/477 (15%) Query: 381 HNKSVIIIGAGPAGLAAARQL------HNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 K V+IIG G GLAAA + N +++T++EA R+GG++ K G + R Sbjct: 4 GKKHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKK-DGYIIER 62 Query: 435 GA-QIVNGCINNPVALMCEQLGIS----MHKFGERCDLIQEGGRITDPTIDKRMDFHFNA 489 G + + P + + LG+ + G+ L+ + Sbjct: 63 GPDSFLERKKSAPQ--LVKDLGLEHLLVNNATGQSYVLVNRTLHPMPKGAVMGIPTKIAP 120 Query: 490 LLD-----------------VVSEWRKDKTQLQDVPLGEKIEEIYKAFIKE-------SG 525 + + + KD L + +E+ + I+ Sbjct: 121 FVSTGLFSLSGKARAAMDFILPASKTKDDQSLGEFFRRRVGDEVVENLIEPLLSGIYAGD 180 Query: 526 IQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEK 585 I L QF+ + ++ + + + A+ G L+ G ++E+ Sbjct: 181 IDKLSLMSTFPQFYQTEQKHRSLILGMKKTRPQGSGQQLTAKKQGQFQTLSTGLQTLVEE 240 Query: 586 LAEGLD---IQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPP 642 + + L + + V + +SG + +G A V+VT P G + P Sbjct: 241 IEKQLKLTKVYKGTKVTKLSHSGSCYSLELDNGVTLDADSVIVTAPHKAAA-GMLSELPA 299 Query: 643 LSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFA-VFYDMD 701 +S K + + + +AL FP + +G F V S + A + + Sbjct: 300 ISHLKN-----MHSTSVANVALGFPEGSVQMEHEGTGF---VISRNSDFAITACTWTNKK 351 Query: 702 PQKKHS----VLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRW 757 +L + + S+ L D ++ + L+++ +P VTRW Sbjct: 352 WPHAAPEGKTLLRAYVGKAGDESIVDLSDNDIINIVLEDLKKVM--NINGEPEMTCVTRW 409 Query: 758 STDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQ-TVTGAYLSGV 813 + G + EA +P +TGA GV Sbjct: 410 HE---------SMPQYHVGHKQ---------RIKELREALASAYPGVYMTGASFEGV 448 >4IVM-B nrPDB Length = 483 Score = 71.0 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 57/357 (15%), Positives = 121/357 (33%), Gaps = 48/357 (13%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGI--KVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 ++V+++G G +GLAA+ L KV ++E+ +R+GG + + G G + Sbjct: 8 GRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPGGI 67 Query: 440 --NGCINNPVALMCEQLGI--------SMHKFGERCDLIQEGGRITDPT---------ID 480 G + L+ +LG+ H + L G PT Sbjct: 68 RPAGALGARTLLLVSELGLDSEVLPVRGDHPAAQNRFLYVGGALHALPTGLRGLLRPSPP 127 Query: 481 KRMDFHFNALLDVVSEWRKDKTQ---------LQDVPLGEKIEEIYKAFIKESGIQFSEL 531 + L ++ K+ + L ++ + + + + S Sbjct: 128 FSKPLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVASLAMDSLCRGVFAGNSRELSIR 187 Query: 532 EGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHT----LLTPGYSVIIEKL- 586 F + L + R+ + + A L G ++ + L Sbjct: 188 SCFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQALAERWSQWSLRGGLEMLPQALE 247 Query: 587 ----AEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPP 642 + G+ + PV + + + + A V+ +P ++L + P Sbjct: 248 THLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPASVLSELLPAEAAP 307 Query: 643 LSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYD 699 L +A++++ A + + LQ+ + FGH+ PS+ G+ + YD Sbjct: 308 L----ARALSAITAVSVAVVNLQYQGAHLPVQG-----FGHLVPSSEDPGVLGIVYD 355 >3LXD-A nrPDB Length = 415 Score = 69.0 bits (167), Expect = 8e-12, Method: Composition-based stats. Identities = 22/54 (40%), Positives = 31/54 (57%) Query: 371 ADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDD 424 AD+ + D K+ ++IG G GL AA L FG+ VT+LEA R+ RV + Sbjct: 141 ADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGE 194 >3K30-A nrPDB Length = 690 Score = 67.1 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 43/223 (19%), Positives = 76/223 (34%), Gaps = 16/223 (7%) Query: 367 LSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS 426 G + + V+++GAGP+GL AAR L G V + EA +GGRV + + Sbjct: 376 WRRGWHPERIRAKESDARVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRVTQESA 435 Query: 427 FKGVT----VGRGAQIVNGCINNP-VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDK 481 G++ V + V + N + G + +FG + G + Sbjct: 436 LPGLSAWGRVKEYREAVLAELPNVEIYRESPMTGDDIVEFGFEHVITATGATWRTDGV-A 494 Query: 482 RMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLS 541 R + + + D +P G+K+ + + Sbjct: 495 RFHTTALPIAEGMQVLGPDDLFAGRLPDGKKV-------VVYDDDHYYLGGVVAELLAQK 547 Query: 542 NLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIE 584 E + + QVS SW N F L+ G + + + Sbjct: 548 GYEVSIVTPGAQVS--SW-TNNTFEVNRIQRRLIENGVARVTD 587 >1I8T-A nrPDB Length = 367 Score = 65.6 bits (158), Expect = 1e-10, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 91/249 (36%), Gaps = 19/249 (7%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 II+G+G G A +L KV V+E ++ IGG + + +G+ + + + Sbjct: 1 MYDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTE-DCEGIQIHKYGAHIFH 59 Query: 442 CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDK 501 + + L + ++F I + P + + D Sbjct: 60 TNDKYIWDYVNDL-VEFNRFTNSPLAIYKDKLFNLP-FNMNTFHQMWGVKDPQEAQNIIN 117 Query: 502 TQ--LQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSW 559 Q + E +EE + + E Q Q+ S E ++ Sbjct: 118 AQKKKYGDKVPENLEEQAISLVGEDLYQALIKGYTEKQWGRSAKELPAFIIKRIPVRFTF 177 Query: 560 DHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYS 619 D+N F ++ G + GY+ +IEK+ EG+D++L ID+ D D Sbjct: 178 DNNYFSDRYQG---IPVGGYTKLIEKMLEGVDVKLG-----IDFLKD------KDSLASK 223 Query: 620 AQKVLVTVP 628 A +++ T P Sbjct: 224 AHRIIYTGP 232 >4RPJ-A nrPDB Length = 399 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 54/387 (13%), Positives = 121/387 (31%), Gaps = 38/387 (9%) Query: 383 KSVIIIGAGPAGLAAA-RQLHNFGIKVTVLEAKDRIGGRVWDD-KSFKGVTVGRGAQIVN 440 + ++G+G GL A R +V VLE + IGG + + + G+ V + + Sbjct: 8 FDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLF 67 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKD 500 N V Q + R + G P + F + Sbjct: 68 HTSNKRVWDYVRQF-TDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLI 126 Query: 501 KTQLQDVPLGEK--IEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARS 558 Q ++ + +EE + I + Q+ E + + Sbjct: 127 AEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYT 186 Query: 559 WDHNEFFAQFAGDHTLLTPGYSVIIEKLAEG--LDIQLK-------------SPVQCIDY 603 +D+ F + G L T GY+ ++ +A ++++L SP + Y Sbjct: 187 FDNRYFSDTYEG---LPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVY 243 Query: 604 SGD-EVQVTTTDGTG--YSAQKVLVTVPLALLQKGAI--QFNPPLSEKKMKAINSLG--- 655 +G + +G + + +P+ Q A+ + + ++ Sbjct: 244 TGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPER 303 Query: 656 -AGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIA 714 + + ++ RF + + + + + R L A + + S + Sbjct: 304 DYRTDKTVIMREYSRFAEDDDEPY----YPINTEADRALLATYRARAKSETASSKVLF-- 357 Query: 715 GEAVASVRTLDDKQVLQQCMATLRELF 741 G + + + LD + + + Sbjct: 358 GGRLGTYQYLDMHMAIASALNMYDNVL 384 >5ZBC-A nrPDB Length = 451 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 60/454 (13%), Positives = 137/454 (30%), Gaps = 58/454 (12%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNF----GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 H+ + I+GAG +GL A L + G+ + + + + GGR+ ++ G Sbjct: 22 KHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKMLDGKASIELG 81 Query: 436 AQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS 495 A +P +M + ++ ++ P + H L Sbjct: 82 A-GRYSPQLHP------HFQSAMQHYSQKSEVY--------PFTQLKFKSHVQQKLKRA- 125 Query: 496 EWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVS 555 + +L++ ++ + + +S + + + + L + + Sbjct: 126 -MNELSPRLKEHGKESFLQFVSRYQGHDSAVGMI----RSMGYDALFLPDISAEMAYDIV 180 Query: 556 ARSWDHNEFFAQFAGDHTLLTPGYSVIIEKL-----AEGLDIQLKSPVQCIDYSGDEVQV 610 + + A G++ +I+ + A G L + + GD + Sbjct: 181 GKHPEIQSVTDNDANQWFAAETGFAGLIQGIKAKVKAAGARFSLGYRLLSVRTDGDGYLL 240 Query: 611 TTTDGTGY----SAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQF 666 G+ + +++ +P + + + F P SL K L + Sbjct: 241 QLAGDDGWKLEHRTRHLILAIPPSAMAGLNVDF-PE--AWSGARYGSLPL---FKGFLTY 294 Query: 667 PYRFW-DSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLD 725 +W D K+ P + + + +A + + Sbjct: 295 GEPWWLDYKLDDQVLIVDNPLRKIYFKGDKYLFFYTDSEMANYWRGCVAEGEDGYLEQI- 353 Query: 726 DKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAED 785 + L + +RE +P P + W+ F + ++ Sbjct: 354 -RTHLASALGIVRE-----RIPQPLAHVHKYWAH------GVEFCRDSDIDHP-SALSHR 400 Query: 786 IQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 819 G + A + G LS REAS++ Sbjct: 401 DSGII--ACSDAYTEHAGWMEGGLLSA-REASRL 431 >5NMX-A nrPDB Length = 425 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 + V ++GAGP+GL AAR L G +V V E +GG W+ ++ G + + Sbjct: 1 MRRVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGG-TWNYTDETWMS-EDGRPVYSS 58 Query: 442 CINNPVALMCEQL 454 N + ++L Sbjct: 59 MYQNLFVNLPKEL 71 >5BR7-A nrPDB Length = 393 Score = 59.4 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 39/217 (17%), Positives = 80/217 (36%), Gaps = 8/217 (3%) Query: 382 NKSVIIIGAGPAGLAAA-RQLHNFGIKVTVLEAKDRIGGRVWDD-KSFKGVTVGRGAQIV 439 + +I++G+G GL A R G KV ++E + +GG + + + G+ + + + Sbjct: 3 DFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHL 62 Query: 440 NGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNAL--LDVVSEW 497 N V Q + + R + G P ++ F D E Sbjct: 63 FHTSNKRVWDYVNQF-TAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEAREL 121 Query: 498 RKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSAR 557 K+++ D +EE + I + + Q+ E G+ Sbjct: 122 IKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRY 181 Query: 558 SWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQL 594 ++D+ F + G L GY+ + +A+ +I++ Sbjct: 182 NFDNRYFNDTYEG---LPVDGYAQWLSNMADHENIEV 215 >5VJ7-A nrPDB Length = 476 Score = 59.0 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 26/125 (20%) Query: 309 ALRNLILALWYTNCKEALTPQKCIPHIIVRG---------LVRIRCVQEVER-ILYFMTR 358 A+R + +W N A+T + C G + I ++ER + + Sbjct: 79 AVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIG---KLERFVADYARE 135 Query: 359 KGLINTGVLSVGADQYLLPKDYH----NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 G D+ LL + K V IIGAGPAGL A L G +VT+ EA Sbjct: 136 HG---------IDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL 186 Query: 415 DRIGG 419 + GG Sbjct: 187 HQPGG 191 >5JFC-L nrPDB Length = 474 Score = 59.0 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 26/125 (20%) Query: 309 ALRNLILALWYTNCKEALTPQKCIPHIIVRG---------LVRIRCVQEVER-ILYFMTR 358 A+R + +W N A+T + C G + I ++ER + + Sbjct: 79 AVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIG---KLERFVADYARE 135 Query: 359 KGLINTGVLSVGADQYLLPKDYH----NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 G D+ LL + K V IIGAGPAGL A L G +VT+ EA Sbjct: 136 HG---------IDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL 186 Query: 415 DRIGG 419 + GG Sbjct: 187 HQPGG 191 >2UZZ-A nrPDB Length = 372 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 62/343 (18%), Positives = 102/343 (29%), Gaps = 62/343 (18%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 +IIIG+G G AA G+ V + +A S G T G Sbjct: 4 DLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPP----HQHGSHHGDTRLIRHAYGEGEK 59 Query: 444 NNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQ 503 P+ L + L + + E + G I D + +W+ + + Sbjct: 60 YVPLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPAD---STFLANVAHSAEQWQLNVEK 116 Query: 504 LQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNE 563 L + + EI + ++ I E + G +++ ++W Sbjct: 117 LDAQGIMARWPEIR---VPDNYIGLFETD--------------SGFLRSELAIKTWIQ-- 157 Query: 564 FFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKV 623 A+ AG L PV I + D V + T DG Y A+K Sbjct: 158 -LAKEAGCAQL-------------------FNCPVTAIRHDDDGVTIETADGE-YQAKKA 196 Query: 624 LVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGH 683 +V K + P +K+ A K +F F G Sbjct: 197 IVCA--GTWVKDLLPELPVQPVRKVFAWYQADGRYSVK------NKF-------PAFTGE 241 Query: 684 VPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDD 726 +P G A + K + + A E V + D Sbjct: 242 LPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSD 284 >3KYB-A nrPDB Length = 390 Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 43/227 (18%), Positives = 83/227 (36%), Gaps = 8/227 (3%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS-FKGVTVGRGAQIVN 440 +K ++I+GAG +G RQL G +V +++ +D IGG +D + V V + Sbjct: 3 SKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHIF 62 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKD 500 N V + M + R G + P ++ F+ E R Sbjct: 63 HTDNETVWNYINKHA-EMMPYVNRVKATVNGQVFSLPINLHTINQFFSKTCS-PDEARAL 120 Query: 501 KTQLQDVPLGEK--IEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARS 558 + D + + EE FI + + + Q+ + E S L ++ R Sbjct: 121 IAEKGDSTIADPQTFEEQALRFIGKELYEAFFKGYTIKQWGMQPSELP-ASILKRLPVRF 179 Query: 559 WDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSG 605 + +F + GY+ +I+ + +I++ + I Sbjct: 180 NYDDNYFNH--KFQGMPKCGYTQMIKSILNHENIKVDLQREFIVDER 224 >3UKH-A nrPDB Length = 519 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 67/484 (13%), Positives = 146/484 (30%), Gaps = 63/484 (13%) Query: 384 SVIIIGAGPAGLAAARQL-HNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 V++IGAGP GL AA++L G ++++ + GG D + +G G ++ Sbjct: 8 DVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVTPEGFLYDVGGHVIFSH 67 Query: 443 INNPVALMCEQLGISM--HKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKD 500 + E L + + +G + P + + + Sbjct: 68 YKYFDDCLDEALPKEDDWYTHQRISYVRCQGQWVPYPFQNNISMLPKEEQVKCIDGMIDA 127 Query: 501 KTQLQ-DVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSW 559 + + + +E + + + + C +V+A + Sbjct: 128 ALEARVANTKPKTFDEWIVRMMGTGIADLFMRPYNFKVWAVPTTKMQCAWLGERVAAPNL 187 Query: 560 D---HNEFFAQFAGD-------HTLLTPGYSVIIEKLAEGLD---IQLKSPVQCIDYSGD 606 N + AG+ G I +A L + + + + Sbjct: 188 KAVTTNVILGKTAGNWGPNATFRFPARGGTGGIWIAVANTLPKEKTRFGEKGKVTKVNAN 247 Query: 607 EVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSL------------ 654 VT DGT +K++ T+ + L + + L + S Sbjct: 248 NKTVTLQDGTTIGYKKLVSTMAVDFLAEAM--NDQELVGLTKQLFYSSTHVIGVGVRGSR 305 Query: 655 GAGIIEKIALQFPY---RFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQ------KK 705 I +K L FP F+ + + + P ++ K + PQ Sbjct: 306 PERIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPEASKKLPTMQLADGSRPQSTEAKEGP 365 Query: 706 HSVLMSVIAGEA----------VASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVT 755 + +M ++ + ++ L + ++L+ + + + PT Sbjct: 366 YWSIMLEVSESSMKPVNQETILADCIQGLVNTEMLKPTDEIVSTYHRRFDHGYPTPTLER 425 Query: 756 RWSTDP----------WIQMAYSFVK--TGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQ 803 + W + + + G ++ + E + V A E T ++P Sbjct: 426 EGALTQILPKLQDKDIWSRGRFGSWRYEVGNQDHSFMLGVEAVDNIVNGAVELTL-NYPD 484 Query: 804 TVTG 807 V G Sbjct: 485 FVNG 488 >5EQD-A nrPDB Length = 400 Score = 56.7 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 36/218 (16%), Positives = 70/218 (32%), Gaps = 8/218 (3%) Query: 381 HNKSVIIIGAGPAGLAAA-RQLHNFGIKVTVLEAKDRIGGRVWDD-KSFKGVTVGRGAQI 438 N + ++G+G GL A R G +V V+E + IGG + + + G+ V + Sbjct: 3 GNFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYSEPEPETGIEVHKYGAH 62 Query: 439 VNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWR 498 + N V Q + R + G P + F Sbjct: 63 LFHTSNKRVWDYVRQF-TDFTGYQHRVFAMHNGQAYQFPMGLGLVSQFFGRYFSPDEARA 121 Query: 499 KDKTQLQDVPL--GEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSA 556 Q ++ + EE + + + Q+ + + Sbjct: 122 LIAEQASEIDTKDAKNFEEKAISLVGRPLYEAFIKHYTAKQWQTDPKDLPASNITRLPVR 181 Query: 557 RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQL 594 ++D+ F + G L GY+ +E +A I++ Sbjct: 182 YTFDNRYFNDTYEG---LPVEGYTKWLENMAADERIEV 216 >3BHF-A nrPDB Length = 390 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 89/272 (32%), Gaps = 52/272 (19%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 + VI++GAG G+AA QL G+K +++A D + S G T Sbjct: 2 STHFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPP----HTNGSHHGDTKIIRHAYG 57 Query: 440 NGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRK 499 G P+AL ++L + K + G + P F ++ E Sbjct: 58 EGREYVPLALRSQELWYELEKETHHKIFTKTGVLVFGP--KGESAF-VAETMEAAKEHSL 114 Query: 500 DKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSW 559 L+ + ++ I + E+ E G + R+ Sbjct: 115 TVDLLEGDEINKRWPGI---TVPENYNAI--------------FEPNSGVLFSENCIRA- 156 Query: 560 DHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYS 619 Y + E G + + V+ D S D V++ T +G Y+ Sbjct: 157 -------------------YRELAEA--RGAKVLTHTRVEDFDISPDSVKIETANG-SYT 194 Query: 620 AQKVLVTVPLALLQKGAIQ---FNPPLSEKKM 648 A K++V+ + + + PL + Sbjct: 195 ADKLIVS--MGAWNSKLLSKLNLDIPLQPYRQ 224 >4MO2-B nrPDB Length = 368 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 34/217 (15%), Positives = 73/217 (33%), Gaps = 9/217 (4%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 +I+G+G G A + G V+E ++ IGG + + + K + V + + Sbjct: 1 MYDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNCYTE-NIKNINVHKYGAHIFR 59 Query: 442 CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDK 501 + + Q + F I + P F + +E RK Sbjct: 60 TSDQNIWDYMNQF-CEFNHFINSPIAIYKDEIYNLPF--NMNTFSKLWGIKTPNEARKII 116 Query: 502 TQLQDVPLG--EKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSW 559 + + + +EE + + + Q+ S + S + ++ R Sbjct: 117 EMQKQIIQHPPKNLEEQAISLVGTDVYEKLIKGYTEKQWGRSCKDLP-ASIIRRLPVRYI 175 Query: 560 DHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKS 596 N +F + GY+ I +K+ + + L + Sbjct: 176 YDNNYFND--PYQGIPKGGYTAIFDKMLKKSKVILNT 210 >4ZCC-A nrPDB Length = 336 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 + IIG G AGL+AA+ L + G +V + + GGR+ +S G ++ GAQ Sbjct: 4 PIAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAG-SLDMGAQYFT-AR 61 Query: 444 NNPVALMCEQ 453 + A +Q Sbjct: 62 DRRFATAVKQ 71 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 34/248 (13%), Positives = 70/248 (28%), Gaps = 38/248 (15%) Query: 577 PGYSVIIEKLAEGLDIQLKSPVQCI---DYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQ 633 PG S I + L + + + + + + + + +S V++ P Sbjct: 107 PGMSAITRAMRGDLPVSFSCRITDVFRGEQHWNLLDAESENHGPFS--HVIIATPAPQAT 164 Query: 634 KGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGL 693 + K + + +AL F G L Sbjct: 165 ALLAA-----APKLASVVAGVKMDPTWAVALAFETPLQTP------MQGCFV---QDSPL 210 Query: 694 FAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQE---VPDPT 750 + + + L S + A + + +Q + L F E +P P Sbjct: 211 DWLARNRSKPGRDDTLDSWVL-HATSQWSRQNLDASREQVIEHLHGAFAELIDCAMPAPV 269 Query: 751 KYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYL 810 RW + + + +++ G ++ G+ V GA+L Sbjct: 270 FSLAHRWL---YAR--------PAGSHEWGALSDADLG-IYVCGDWCL---SGRVEGAWL 314 Query: 811 SGVREASK 818 SG A + Sbjct: 315 SGQEAARR 322 >3KKJ-A nrPDB Length = 336 Score = 50.6 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 + IIG G AGL+AA+ L G +V + + GGR+ +S G + GAQ Sbjct: 4 PIAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGA-LDMGAQYFT-AR 61 Query: 444 NNPVALMCEQ 453 + A +Q Sbjct: 62 DRRFATAVKQ 71 Score = 34.4 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 33/245 (13%), Positives = 69/245 (28%), Gaps = 32/245 (13%) Query: 577 PGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGA 636 PG S I + + + + + + + +G + ++ A Sbjct: 107 PGMSAITRAMRGDMPVSFSCRITEVFRGEEHWNLLDAEGQNHGPFSHVIIATPAPQASTL 166 Query: 637 IQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAV 696 + P L + + +AL F G L + Sbjct: 167 LAAAPKL----ASVVAGVKMDPTWAVALAFETPLQTP------MQGCFV---QDSPLDWL 213 Query: 697 FYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQE---VPDPTKYF 753 + ++ L + I A + + +Q + L F E +P P Sbjct: 214 ARNRSKPERDDTLDTWIL-HATSQWSRQNLDASREQVIEHLHGAFAELIDCTMPAPVFSL 272 Query: 754 VTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGV 813 RW + + + +++ G ++ G+ V GA+LSG Sbjct: 273 AHRWL---YAR--------PAGAHEWGALSDADLG-IYVCGDWCL---SGRVEGAWLSGQ 317 Query: 814 REASK 818 A + Sbjct: 318 EAARR 322 >2IVE-A nrPDB Length = 478 Score = 50.6 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 43/116 (37%), Gaps = 5/116 (4%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 +P+ +V ++G G +GLA A L + G +LE+ R+GG V + G V +G Sbjct: 11 MPRTTGM-NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGT-HALAGYLVEQG 68 Query: 436 AQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALL 491 AL +++ D + + + + A L Sbjct: 69 PNSFLDREPATRALAAA---LNLEGRIRAADPAAKRRYVYTRGRLRSVPASPPAFL 121 >4UIR-A nrPDB Length = 646 Score = 49.8 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 54/279 (19%), Positives = 100/279 (35%), Gaps = 35/279 (12%) Query: 378 KDYHNKSVIIIGAGPAGLAAARQLHNFGI----KVTVLEAKDRIGGRVWDDKSFKGVTVG 433 + Y N + IIG+G AG++AA G +T LE GG + + + Sbjct: 58 QSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSLDGAGNPTDGYII 117 Query: 434 RGAQIVNGCINNPVALMCEQLGISM---HKFGERCDLIQEGGRITDPTIDKRMDFHFNAL 490 RG + ++ N + + + M + + LI + Sbjct: 118 RGGREMDMTYENLWDMFQDIPALEMPAPYSVLDEYRLINDNDSNYSKARLINNKGEIKDF 177 Query: 491 ----------LDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFH- 539 L ++ K+K +L D+ + + E +F+K + F +H Sbjct: 178 SKFGLNKMDQLAIIRLLLKNKEELDDLTIEDYFSE---SFLKSNFWTFWRTMFAFENWHS 234 Query: 540 LSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQ 599 L L+ LH + + + F ++ T +TP + EK G++I L + V+ Sbjct: 235 LLELKLYMHRFLHAIDGLNDLSSLVFPKYNQYDTFVTPLRKFLQEK---GVNIHLNTLVK 291 Query: 600 CID---YSGDEV---QVTTTDGTGYSA-----QKVLVTV 627 +D + +V +T DG V+VT Sbjct: 292 DLDIHINTEGKVVEGIITEQDGKEVKIPVGKNDYVIVTT 330 >2YQU-A nrPDB Length = 455 Score = 49.4 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 48/273 (17%), Positives = 88/273 (32%), Gaps = 22/273 (8%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG---RV----------WDDKSFK 428 +++IGAGP G AA + G+KV V+E + +GG RV ++ ++ Sbjct: 1 MYDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYE 60 Query: 429 GVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFN 488 G V G + ALM + + L ++ G R Sbjct: 61 AKK-GLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQG-TARFLSERK 118 Query: 489 ALLDVVSEWRKDKTQLQDVPLGEKIEEI-----YKAFIKESGIQFSELEGQVLQFHLSNL 543 L++ E + + L I + + F E+ +++ + Sbjct: 119 VLVEETGEELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKRLIVVGGGVI 178 Query: 544 EYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY 603 G H++ A ++ + +K +GL I+ V + Sbjct: 179 GLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKK--QGLTIRTGVRVTAVVP 236 Query: 604 SGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGA 636 +V G A +VLV V +G Sbjct: 237 EAKGARVELEGGEVLEADRVLVAVGRRPYTEGL 269 >2TMD-A nrPDB Length = 729 Score = 49.4 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 68/203 (33%), Gaps = 5/203 (2%) Query: 367 LSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS 426 G + + SV+I+GAGP+G AAR L G V + + ++IGG + + Sbjct: 374 YRRGWHPEKFRQTKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAA 433 Query: 427 FKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH 486 G+ + + ++ S G++ + + + Sbjct: 434 LPGLG-EW--SYHRDYRETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIATGAR 490 Query: 487 FNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYA 546 +N D + D D L +++ K+ + + F +L Sbjct: 491 WNT--DGTNCLTHDPIPGADASLPDQLTPEQVMDGKKKIGKRVVILNADTYFMAPSLAEK 548 Query: 547 CGSNLHQVSARSWDHNEFFAQFA 569 + H+V+ S H + F Sbjct: 549 LATAGHEVTIVSGVHLANYMHFT 571 >4YRY-B nrPDB Length = 468 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 9/76 (11%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 V ++G+GPAGL AA L G V + EA + GG + G + I Sbjct: 142 KVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGG---------VLVYGIPEFRLPKRI 192 Query: 444 NNPVALMCEQLGISMH 459 +LG++ H Sbjct: 193 VEREVSYIRKLGVNFH 208 >2CVJ-A nrPDB Length = 180 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 44/111 (39%), Gaps = 7/111 (6%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLE-AKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 VI++G GP+GL+AA L G+KV VL+ + ++ G V ++ G+ + Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKG-VSRVPNYPGLLDEPSGE----E 57 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDV 493 + + + G + + G + GG T + L Sbjct: 58 LLRRLEAHARRYGAEV-RPGVVKGVRDMGGVFEVETEEGVEKAERLLLCTH 107 >3MJ4-A nrPDB Length = 397 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 33/227 (14%), Positives = 75/227 (33%), Gaps = 6/227 (2%) Query: 377 PKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGA 436 ++ +I+GAG AG A +L + G +V +++ + IGG +D GV + Sbjct: 24 QQESKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYDDAGVLIHPYG 83 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSE 496 + + V + + R +G + P ++ + L Sbjct: 84 PHIFHTNSKDVFEYLSRF-TEWRPYQHRVLASVDGQLLPIPINLDTVNRLYGLNLTSFQV 142 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSA 556 + + V E++ + + Q+ L E + Sbjct: 143 EEFFASVAEKVEQVRTSEDVVVSKVGRDLYNKFFRGYTRKQWGLDPSELDASVTARVPTR 202 Query: 557 RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQ--LKSPVQCI 601 + D+ F + + GY+ + + + +I+ L + + I Sbjct: 203 TNRDNRYFADTY---QAMPLHGYTRMFQNMLSSPNIKVMLNTDYREI 246 >4OVI-A nrPDB Length = 542 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 V+++GAG +GL A +L G V V+E +GG VW + G Sbjct: 18 DVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG-VWYWNRYPGARCDI 67 >3UP5-A nrPDB Length = 545 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 ++IGAG G+ A ++ G+KV +EA + +GG W + G + Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGG-TWYWNRYPGCRLDT 60 >4Y4M-A nrPDB Length = 290 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 11/114 (9%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 V+I+GAGP+GL AR L G KV VLE R IV Sbjct: 60 ADVVIVGAGPSGLTCARYLAKEGFKVVVLE-------RHLAFGGGTWGGGMGFPYIVV-- 110 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSE 496 P + ++GI + G+ + + + MD L +V E Sbjct: 111 -EEPADELLREVGIKLIDMGD-GYYVADSVEVPAKLAVAAMDAGAKILTGIVVE 162 >1NHQ-A nrPDB Length = 447 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 32/196 (16%), Positives = 64/196 (32%), Gaps = 3/196 (1%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 +V++IG+G G+ AA G KVTV++ DR G D + +T A + Sbjct: 151 NVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIAT 210 Query: 444 NNPVALM---CEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKD 500 V + K DL+ + T + + + ++ Sbjct: 211 GETVERYEGDGRVQKVVTDKNAYDADLVVVAVGVRPNTAWLKGTLELHPNGLIKTDEYMR 270 Query: 501 KTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWD 560 ++ +G+ Y E I + + +F + NLE + Sbjct: 271 TSEPDVFAVGDATLIKYNPADTEVNIALATNARKQGRFAVKNLEEPVKPFPGVQGSSGLA 330 Query: 561 HNEFFAQFAGDHTLLT 576 ++ G + ++ Sbjct: 331 VFDYKFASTGINEVMA 346 >2Q7V-A nrPDB Length = 325 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 4/86 (4%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW---DDKSFKGVT 431 + H+ V+IIG GPAGL AA + +LE K GG++ + ++F G Sbjct: 1 MTAPTAHDYDVVIIGGGPAGLTAAIYTGRAQLSTLILE-KGMPGGQIAWSEEVENFPGFP 59 Query: 432 VGRGAQIVNGCINNPVALMCEQLGIS 457 + ++ ++ + Sbjct: 60 EPIAGMELAQRMHQQAEKFGAKVEMD 85 >4REP-A nrPDB Length = 495 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 103/311 (33%), Gaps = 38/311 (12%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 K+ I+IGAG GLAAA +L + G VT+ E D GG++ + G G + Sbjct: 1 MKNAIVIGAGIGGLAAALRLRHQGYSVTIFEKNDYAGGKLHAIEK-DGYRFDLGPSLFTL 59 Query: 442 CI--NNPVALMCEQL--------GISMHKFGERCDLIQ----EGGRITD--PTIDKRMDF 485 N AL E++ IS H F + L + I D + Sbjct: 60 PHLVENLFALFPEEIIDFGYKSKAISFHYFWDDGTLFKASTDSSQFIEDASKVFKEEKST 119 Query: 486 HFNALLDVVSEWRKDKTQLQDVPLGEK--------IEEIYKAFIKESGIQFSELEGQVLQ 537 L S++ K+ + L + ++ I A ++ + Sbjct: 120 IKKYLAKSKSKYELTKSLFLEKSLHKATTYFSLDTVKAIVHAPFLGLNNTLNDENSKFKN 179 Query: 538 FHLSNLEY----ACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAE----- 588 L+ L GS+ +Q + G I + L E Sbjct: 180 PKLTQLFNRYATYNGSSPYQTPGIMTMIPHL--ELGLGTYYPDGGMHRISQSLFELAQKV 237 Query: 589 GLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKM 648 G+ + + V I S ++V T Y + V+ + + + ++ P +K Sbjct: 238 GVKFRFRESVTNITTSKNKVTGVETKNGSYLSDLVVSNMDIVPTYRNLMKDVPA--PEKT 295 Query: 649 KAINSLGAGII 659 + + +I Sbjct: 296 LSQERSSSALI 306 >4Y4N-A nrPDB Length = 286 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 41/116 (35%), Gaps = 11/116 (9%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 + V I+G GP+GL AAR + G KV VLE R IV Sbjct: 52 DVDVAIVGGGPSGLTAARYIAKEGYKVVVLE-------RHLAFGGGTWGGGMGFPYIVV- 103 Query: 442 CINNPVALMCEQLGISMHKF-GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSE 496 P + ++G+ + K GE + + +D L +V E Sbjct: 104 --EEPADEILREVGVKLEKVEGEDGLYTADSVEVPAKLAVGAIDAGAKVLTGIVVE 157 >1ZOV-A nrPDB Length = 386 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 4/98 (4%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 + VI++GAG G+AA L G+K ++++ D + S G T Sbjct: 1 STHFDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPP----HTNGSHHGDTRIIRHAYG 56 Query: 440 NGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDP 477 G P AL ++L + K Q G + P Sbjct: 57 EGREYVPFALRAQELWYELEKETHHKIFTQTGVLVYGP 94 >6JDK-A nrPDB Length = 544 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 31/139 (22%), Positives = 48/139 (34%), Gaps = 18/139 (12%) Query: 368 SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSF 427 SV + Q D +I+GAG G+ +L G KV + EA +GG +W + Sbjct: 3 SVQSSQTQKNDDAEVFDALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGG-IWYWNCY 61 Query: 428 KGVTVGRGAQIV-----------NGCINNPVALMCEQLGISMHKFGERCDLIQE---GGR 473 G V I N P + H ++ DL ++ G R Sbjct: 62 PGARVDSHIPIYEFSIEELWRDWNWTERFPAWDELRRY---FHYVDKKLDLSRDIRFGMR 118 Query: 474 ITDPTIDKRMDFHFNALLD 492 ++ D+ D D Sbjct: 119 VSAAEFDEARDQWVIRTTD 137 >6N7F-A nrPDB Length = 453 Score = 45.9 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 40/264 (15%), Positives = 83/264 (31%), Gaps = 24/264 (9%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 I+IG G AG+A+A + G KV + E K+ IGG + + GAQ+ Sbjct: 7 PYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKE-IGGTCVNLGCVPKKVMWYGAQVA-- 63 Query: 442 CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFN-----ALLDVVSE 496 + + + G + ++ + I + F + D Sbjct: 64 ---DILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVF 120 Query: 497 WR----KDKTQLQDVPL-------GEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEY 545 + QL P +I A S F L+ + + Y Sbjct: 121 KDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGY 180 Query: 546 ACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLA-EGLDIQLKSPV-QCIDY 603 + A + F + V+++++A G + + V + + Sbjct: 181 IAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKN 240 Query: 604 SGDEVQVTTTDGTGYSAQKVLVTV 627 + + + + DG +++ + Sbjct: 241 TDESLTLYLKDGQEVEVDQLIWAI 264 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 38/111 (34%), Gaps = 8/111 (7%) Query: 367 LSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS 426 + +D + D K ++GAG + A LH G K + DR R +D Sbjct: 156 YGISSDGFFA-LDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPL-RSFDKTI 213 Query: 427 FKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDP 477 + VNG + A + + + + +++G + Sbjct: 214 VDVLVDEMA---VNGPRLHTHAEVAK---VVKNTDESLTLYLKDGQEVEVD 258 >3JSK-A nrPDB Length = 344 Score = 45.5 bits (106), Expect = 9e-05, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 15/95 (15%) Query: 373 QYLLPKDYHNK-SVIIIGAGPAGLAAARQLH--NFGIKVTVLEAKDRIGGRVWDDKSFKG 429 +Y D H + ++I+GAG GL+AA L +++T++EA GG W Sbjct: 69 RYFADLDAHAETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW------- 121 Query: 430 VTVGRGAQIVNG-CINNPVALMCEQLGISMHKFGE 463 G Q+ + + P + +++G+ G+ Sbjct: 122 ----LGGQLFSAMVMRKPADVFLDEVGVPYEDEGD 152 >3R9U-A nrPDB Length = 315 Score = 45.5 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW---DDKSFKGVTVGRGAQIVN 440 V IIG GPAGL+A G+K V+ K GG++ + +++ GV AQ+++ Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGV-----AQVMD 60 Query: 441 G-CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRK 499 G P + C + G+ G L G T + + ++ S +K Sbjct: 61 GISFMAPWSEQCMRFGLKHEMVGVEQILKNSDGSFTIKLEGGKTELAKAVIVCTGSAPKK 120 Query: 500 DKTQLQDVPLGEKIEE 515 + +D G+ + Sbjct: 121 AGFKGEDEFFGKGVST 136 >4X4J-A nrPDB Length = 507 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 4/54 (7%) Query: 375 LLPKDYH-NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSF 427 L+P+ H + V+I GAGPAGL A +L GI V VLE R+ R + + Sbjct: 14 LVPRGSHMDAPVVIAGAGPAGLMLAGELRLAGIGVVVLE---RLPARTGESRGL 64 >5GJK-A nrPDB Length = 94 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 7/80 (8%) Query: 287 DVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCV 346 + L E + S+ P +YLA RN ++ + N +E LT C ++ V Sbjct: 21 ERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGD-------V 73 Query: 347 QEVERILYFMTRKGLINTGV 366 V R+ F+ + GL+N V Sbjct: 74 CAVMRVHAFLEQWGLVNYQV 93 >5J5Z-A nrPDB Length = 496 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 43/288 (14%), Positives = 91/288 (31%), Gaps = 39/288 (13%) Query: 370 GADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKG 429 GADQ + + V +IG+GP G AA + G K +E + +GG + Sbjct: 22 GADQPI------DADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPS 75 Query: 430 VTVGRGAQIVNGCINNPVA---LMCEQLGISMHKFGER------------CDLIQEGGRI 474 + + + A + ++ +++ K E+ L ++ + Sbjct: 76 KALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVV 135 Query: 475 TDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGI-------Q 527 K + + T+ + G ++ I E I Sbjct: 136 HVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALS 195 Query: 528 FSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFA--GDHTLLTPGYSVIIEK 585 ++ +++ + GS ++ A EF G ++ + I++K Sbjct: 196 LKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNFQRILQK 254 Query: 586 LAEGLDIQLKSPVQCIDYSGDE---VQVTTTDG---TGYSAQKVLVTV 627 +G +L + V D V + G + +LV + Sbjct: 255 --QGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCI 300 >5UTH-A nrPDB Length = 319 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 35/109 (32%), Gaps = 3/109 (2%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG--RVWDDKSFKGVTVG 433 + VIIIG+GPAG AA +K V E G + +++ G G Sbjct: 9 MSTSQTVHDVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGGALMTTTEVENYPGFREG 68 Query: 434 RGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKR 482 + + L + + ++ + D T R Sbjct: 69 ITGPELMDQMREQALRFGADLRMEDVDAVQLEGPVKTV-VVGDETHQAR 116 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 19/34 (55%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 ++ ++++G G + + A L F VT++ +D Sbjct: 155 DQDIVVVGGGDSAMEEATFLTRFARSVTLIHRRD 188 >1PS9-A nrPDB Length = 671 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 54/277 (19%), Positives = 88/277 (31%), Gaps = 35/277 (12%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVT--VGRGAQIVN 440 K++ ++GAGPAGLA A G +VT+ +A IGG+ K G Sbjct: 374 KNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYY-- 431 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNAL---LDVVSEW 497 M E G+++ K + + + D TI +D Sbjct: 432 -------RRMIEVTGVTL-KLNHT--VTADQLQAFDETILASGIVPRTPPIDGIDHPKVL 481 Query: 498 RKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNL--EYACGSNLHQVS 555 P+G K+ I I + G+ +++ E+ S+L Q Sbjct: 482 SYLDVLRDKAPVGNKVAIIGCGGIGFDTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAG 541 Query: 556 ARSWDHNEF------------FAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY 603 S + A G T G+ L+ G+ + Q ID Sbjct: 542 GLSPQGMQIPRSPRQIVMLQRKASKPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDD 601 Query: 604 SGDEVQVTTTDGTGYSAQKVLVTV---PLALLQKGAI 637 G V V + + V++ P L + I Sbjct: 602 DGLHV-VINGETQVLAVDNVVICAGQEPNRALAQPLI 637 >5TR3-A nrPDB Length = 481 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 92/278 (33%), Gaps = 38/278 (13%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRV--------------------- 421 V++IGAGP G AA + G+K +E G++ Sbjct: 8 FDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALLDSS 67 Query: 422 WDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDK 481 W K K + + A++ + GI + G L + G + K Sbjct: 68 WKYKEAK-ESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGK 126 Query: 482 RMDFHFN---------ALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELE 532 + +++ + ++ D+P + + Q Sbjct: 127 LLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAVPKR 186 Query: 533 GQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDI 592 V+ + LE GS ++ A T ++ + K +GLDI Sbjct: 187 LGVIGAGVIGLE--LGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTK--QGLDI 242 Query: 593 QLKSPVQCIDYSGDEVQVTTTDGTG---YSAQKVLVTV 627 +L + V +G+EV+VT T+ G + K++V V Sbjct: 243 KLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAV 280 Score = 36.3 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 19/40 (47%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 L K + +IGAG GL G +VTVLEA D Sbjct: 178 LEFQAVPKRLGVIGAGVIGLELGSVWARLGAEVTVLEALD 217 >2A87-A nrPDB Length = 335 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 32/102 (31%), Gaps = 2/102 (1%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG--RVWDDKSFKGVTVGRGAQIVN 440 + VI+IG+GPAG AA + V E G D +++ G G + Sbjct: 15 RDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELM 74 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKR 482 + L + + ++ T R Sbjct: 75 DEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRAR 116 >4AP1-A nrPDB Length = 549 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 + V+++GAG AGL A + + G+ V EA +GG VW + G Sbjct: 20 TSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGG-VWYWNRYPGARCDV 72 >1V59-A nrPDB Length = 478 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 43/260 (16%), Positives = 84/260 (32%), Gaps = 34/260 (13%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG---------------------R 420 + V+IIG GPAG AA + G +E + ++GG + Sbjct: 5 SHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQ 64 Query: 421 VWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQL--GISMHKFGERCDLIQEGGRITDPT 478 + + +G+ V +I +QL GI + + + G D T Sbjct: 65 MHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDET 124 Query: 479 I-------DKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSEL 531 + +LDV + +++ P E EE + + E+ Sbjct: 125 KIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTG--ALSLKEI 182 Query: 532 EGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLD 591 ++ + GS ++ ++ A + ++K +GLD Sbjct: 183 PKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKK--QGLD 240 Query: 592 IQLKSPVQCIDYSGDEVQVT 611 +L + V + D+ V Sbjct: 241 FKLSTKVISAKRNDDKNVVE 260 >1EBD-A nrPDB Length = 455 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 46/274 (16%), Positives = 87/274 (31%), Gaps = 42/274 (15%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 +++GAGP G AA + G KVT++E K +GG + +++ Sbjct: 5 ETLVVGAGPGGYVAAIRAAQLGQKVTIVE-KGNLGGVCLNVGCIPSK------ALISASH 57 Query: 444 NNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQ 503 A E++GI +QE + ++ L ++ K + Sbjct: 58 RYEQAKHSEEMGIKAENVTIDFAKVQEWKASVVKKLTGGVEG-----LLKGNKVEIVKGE 112 Query: 504 LQDVPLGEKI----EEIYKAFIKESGIQFSELEGQVLQFHLSNL------EYACGSNLHQ 553 V + K + I ++ F SN G Sbjct: 113 AYFVDANTVRVVNGDSAQTYTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEVPKS 172 Query: 554 VSARSWDHNEF-----FAQFAGDHTLLTPGYSVII---EKLA---------EGLDIQLKS 596 + + +A F T+L ++ +++A +G+++ + Sbjct: 173 LVVIGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNA 232 Query: 597 PVQCIDYSGDEVQVTTT---DGTGYSAQKVLVTV 627 + + D V VT + A VLVTV Sbjct: 233 LAKGAEEREDGVTVTYEANGETKTIDADYVLVTV 266 Score = 36.7 bits (83), Expect = 0.042, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 361 LINTGVLSVGADQY-LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 L N + D L KS+++IG G G+ NFG KVT+LE I Sbjct: 148 LPNFKFSNRILDSTGALNLGEVPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEI 205 >3FG2-P nrPDB Length = 404 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 3/75 (4%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD---DKSFKGVTVGRGAQIV 439 K V++IGAG GL A G++V V+E R+ RV F G G ++ Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVTPEISSYFHDRHSGAGIRMH 202 Query: 440 NGCINNPVALMCEQL 454 G +A +++ Sbjct: 203 YGVRATEIAAEGDRV 217 >4A6N-B nrPDB Length = 398 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 4/58 (6%) Query: 365 GVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW 422 G++ G+ LL +K+V IIG GP GL A+ L GI V+V E + R++ Sbjct: 13 GLVPRGSHMNLL----SDKNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIF 66 >3IHG-A nrPDB Length = 535 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 25/94 (26%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD-------------------RIGG-- 419 H V+++GAG GL+ A L G++V V+E + RIGG Sbjct: 4 HEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERRPGLSPYPRAAGQNPRTMELLRIGGVA 63 Query: 420 ----RVWDDKSFKGVTVGRGAQIVNGCINNPVAL 449 R D + +G V R A+ V G I V+ Sbjct: 64 DEVVRADDIRGTQGDFVIRLAESVRGEILRTVSE 97 >2QA2-A nrPDB Length = 499 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 27/106 (25%), Positives = 39/106 (36%), Gaps = 15/106 (14%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD-RIG--------GRVWDDKSFKGV 430 + SVI++GAGPAGL A +L G+ V VLE R G R + +G+ Sbjct: 10 RSDASVIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQRTGESRGLGFTARTMEVFDQRGI 69 Query: 431 -----TVGRGAQIVNGCINNPV-ALMCEQLGISMHKFGERCDLIQE 470 V Q G L G+ +++E Sbjct: 70 LPAFGPVETSTQGHFGGRPVDFGVLEGAHYGVKAVPQSTTESVLEE 115 >1RP0-A nrPDB Length = 284 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 35/223 (15%), Positives = 78/223 (34%), Gaps = 27/223 (12%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNF-GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQ 437 Y V+++GAG AGL+AA ++ ++V ++E GG W G Q Sbjct: 36 TYAETDVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW-----------LGGQ 84 Query: 438 IVNGCI-NNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSE 496 + + I P L +++G++ + + +++ T + K + L + V+ Sbjct: 85 LFSAMIVRKPAHLFLDEIGVA-YDEQDTYVVVKHAALFTSTIMSKLLARPNVKLFNAVAA 143 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSA 556 + ++ +G + A + ++ S ++ V++ + Sbjct: 144 ---EDLIVKGNRVGGVVTNW--ALVAQNHHTQSCMDPNVMEAKIVVSSCGHDGPFGATGV 198 Query: 557 RSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQ 599 + PG + AE ++L V Sbjct: 199 KRLKSIGMIDH--------VPGMKALDMNTAEDAIVRLTREVV 233 >5MJK-A nrPDB Length = 327 Score = 42.8 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 8/71 (11%) Query: 375 LLPKDYHN----KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR---VWDDKSF 427 L+P+ H V+IIG+GPAG+ AA +K +LE + GG+ + +++ Sbjct: 13 LVPRGSHMTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLE-RGVPGGQMNNTAEIENY 71 Query: 428 KGVTVGRGAQI 438 G G ++ Sbjct: 72 PGYETIMGPEL 82 Score = 34.4 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 22/36 (61%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 N+ +++IG G + + A L FG VT++ +D++ Sbjct: 163 NQEILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKL 198 >3LAD-A nrPDB Length = 476 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 44/225 (19%), Positives = 74/225 (32%), Gaps = 23/225 (10%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 VI+IGAGP G AA + G+K ++E K +G T G + GC Sbjct: 4 FDVIVIGAGPGGYVAAIKSAQLGLKTALIE----------KYKGKEGKTALGGTCLNVGC 53 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKT 502 I + L H+ + + I PT+ R D L V+ K Sbjct: 54 IPSKALLDSSYKFHEAHESFKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANG 113 Query: 503 QLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHN 562 G+ + ++ + +G N+ A GS ++ D + Sbjct: 114 VTLFEGHGKL--------LAGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQD 165 Query: 563 EFFAQFAGDHTLLTPGYSVIIEKLAEGLDI-----QLKSPVQCID 602 PG +I GL++ +L + V ++ Sbjct: 166 VIVDSTGALDFQNVPGKLGVIGAGVIGLELGSVWARLGAEVTVLE 210 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 14/30 (46%), Positives = 17/30 (56%) Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLEAKDR 416 +IGAG GL G +VTVLEA D+ Sbjct: 185 VIGAGVIGLELGSVWARLGAEVTVLEAMDK 214 >5TWC-A nrPDB Length = 344 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 39/243 (16%), Positives = 82/243 (33%), Gaps = 15/243 (6%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG--RVWDDKSFKGVTVGRGAQIV 439 K V IIG GP+GL A+ + V +++ + +GG R++ +K + G Sbjct: 1 MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYPEK----IIWDIGGIAP 56 Query: 440 NGCINNPVALMCEQLGI--SMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEW 497 C + + L +H D+ ++ R + + + A++ + Sbjct: 57 KPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVIIAIGAG 116 Query: 498 RKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSAR 557 + QL + + ++ +S +F + + + + L++A S Sbjct: 117 IINPKQLDVKGVERY-QLTNLHYVVQSYRRFKDKDVLISGGGNTALDWAHDIAKIAKSVT 175 Query: 558 SWDHNEFFAQFAGDHTLLTPGYSVII------EKLAEGLDIQLKSPVQCIDYSGDEVQVT 611 E + TL+T + + + + V SGD V Sbjct: 176 VVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDRHTVK 235 Query: 612 TTD 614 D Sbjct: 236 FDD 238 >4C5O-A nrPDB Length = 357 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 V++IG G +GL+A L G+ +L+A+ GG Sbjct: 5 DVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGG 40 >5ER0-A nrPDB Length = 518 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 35/99 (35%), Gaps = 5/99 (5%) Query: 373 QYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSF----K 428 Q L+ K + +IGAG G A G VT+++A R+ + + D F + Sbjct: 188 QALIEDAKEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPK-YFDADFTDVIE 246 Query: 429 GVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDL 467 G Q+ G L I K DL Sbjct: 247 QDYRDHGVQLALGETVESFTDSATGLTIKTDKNSYETDL 285 >2GMH-A nrPDB Length = 584 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 14/97 (14%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQL------HNFGIKVTVLEAKDRIG-----GRVWDD 424 + + V+I+GAGPAGL+AA +L H ++V ++E IG G D Sbjct: 29 MERFAEEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACLDP 88 Query: 425 KSFKG---VTVGRGAQIVNGCINNPVALMCEQLGISM 458 ++F+ +GA + + ++ E+ I + Sbjct: 89 RAFEELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPV 125 >4GCM-A nrPDB Length = 312 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 10/95 (10%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW---DDKSFKGVTVGRGAQI 438 + + IIGAGPAG+ AA +K ++E + GG++ + ++F G + G + Sbjct: 6 DFDIAIIGAGPAGMTAAVYASRANLKTVMIE-RGIPGGQMANTEEVENFPGFEMITGPDL 64 Query: 439 VNGCINNPVALMCEQLGISMHKFGERCDLIQEGGR 473 + ++ G +++++G+ + +G Sbjct: 65 ST-----KMFEHAKKFG-AVYQYGDIKSVEDKGEY 93 >4C3X-A nrPDB Length = 530 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 46/145 (31%), Gaps = 11/145 (7%) Query: 375 LLPKDYHNKS------VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS-- 426 L+P+ H + V+++G+G L A G+ VLE DR GG + Sbjct: 14 LVPRGSHMQDWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASI 73 Query: 427 -FKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDF 485 G V A + + N L + + + + ++F Sbjct: 74 WLPGTQVQERAGLPDSTENART--YLRALLGDAESERQDAYVETAPAVVALLEQNPNIEF 131 Query: 486 HFNALLDVVSEWRKDKTQLQDVPLG 510 F A D + T PL Sbjct: 132 EFRAFPDYYKAEGRMDTGRSINPLD 156 >6BRD-A nrPDB Length = 476 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQ 437 VI++G GP GL A +L G++V VLE + R + ++ AQ Sbjct: 1 MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEP-TRQSRAQGLHVRSIEVMAQ 55 Score = 33.2 bits (74), Expect = 0.42, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 16/44 (36%) Query: 583 IEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVT 626 A G +I+ + + D V V DG A+ V+ Sbjct: 107 EHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGC 150 >1NAA-A nrPDB Length = 541 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 15/32 (46%), Positives = 19/32 (59%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 II+GAGP G+ AA +L G KV +LE Sbjct: 1 TPYDYIIVGAGPGGIIAADRLSEAGKKVLLLE 32 >3FPZ-A nrPDB Length = 326 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 15/102 (14%) Query: 366 VLSVGADQYLLPKDYHN-KSVIIIGAGPAGLAAARQLHNF--GIKVTVLEAKDRIGGRVW 422 V +Y D VII+GAG +GL+AA + +KV ++E+ GG W Sbjct: 48 VSRAMTSRYFKDLDKFAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSW 107 Query: 423 DDKSFKGVTVGRGAQIVNG-CINNPVALMCEQLGISMHKFGE 463 G Q+ + + P L ++L I G+ Sbjct: 108 -----------LGGQLFSAMVMRKPAHLFLQELEIPYEDEGD 138 >3URH-A nrPDB Length = 491 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 42/272 (15%), Positives = 91/272 (33%), Gaps = 30/272 (11%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 +I+IG+GP G A + G+KV V+E + GG + + +++ + Sbjct: 27 DLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMFHQAQ 86 Query: 444 N----------NPVALMCEQL------------GISMHKFGERCDLIQEGGRITDPTIDK 481 + NP + + + G+S + D Q G++ Sbjct: 87 HGLEALGVEVANPKLNLQKMMAHKDATVKSNVDGVSFLFKKNKIDGFQGTGKVLGQGKVS 146 Query: 482 RMDFHFNA-LLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHL 540 + +L+ + + + +P E + + ++ ++ Sbjct: 147 VTNEKGEEQVLEAKNVVIATGSDVAGIPGVEVAFDEKTIVSSTGALALEKVPASMIVVGG 206 Query: 541 SNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQC 600 + GS ++ A+ G + ++ K +G+D +L + V Sbjct: 207 GVIGLELGSVWARLGAKVTVVEFLDTILGGMDGEVAKQLQRMLTK--QGIDFKLGAKVTG 264 Query: 601 IDYSGDEVQVTTT-----DGTGYSAQKVLVTV 627 SGD +VT + T A+ VL+ Sbjct: 265 AVKSGDGAKVTFEPVKGGEATTLDAEVVLIAT 296 Score = 35.9 bits (81), Expect = 0.065, Method: Composition-based stats. Identities = 16/44 (36%), Positives = 21/44 (47%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 L + S+I++G G GL G KVTV+E D I G Sbjct: 192 LALEKVPASMIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILG 235 >4P9S-A nrPDB Length = 848 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 37/110 (33%), Gaps = 10/110 (9%) Query: 377 PKDYHNKSVIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 P+ +IIG G G++ A L G+ V +LE + G W Sbjct: 18 PEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLT------- 70 Query: 436 AQIVNGCINNPVALMCE-QLGISMHKFGERCDLIQEGGRITDPTIDKRMD 484 + IN +L + + + + G I T +R+D Sbjct: 71 -TYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD 119 >3ATQ-A nrPDB Length = 453 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 2/39 (5%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD--RIGGR 420 V+IIG G AG +AA QL G+K+ ++++K RIG + Sbjct: 8 DVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDK 46 >4B1B-A nrPDB Length = 542 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 10/81 (12%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 + + ++ ++IG GP G+A+A++ G +V + + + S +G G G Sbjct: 36 VEEHTYDYDYVVIGGGPGGMASAKEAAAHGARVLLFD---------YVKPSSQGTKWGIG 86 Query: 436 AQIVN-GCINNPVALMCEQLG 455 VN GC+ + +G Sbjct: 87 GTCVNVGCVPKKLMHYAGHMG 107 >1DOD-A nrPDB Length = 394 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAK--DRIGGRVWDDKSFKG 429 V IIGAGP+GL + LH GI +LE + D + GR+ +G Sbjct: 4 QVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQG 51 >6ER9-A nrPDB Length = 549 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 48/142 (33%), Gaps = 35/142 (24%) Query: 384 SVIIIGAGPAGLAAARQLH-NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 ++IGAG G+ A +LH G+ V + D GG W + G + Sbjct: 11 DAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGG-TWYWNRYPGALSDTESH----- 64 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEG----GRITDPTI---------DKRMDFHFNA 489 +++F DL+Q+G IT P I + HF Sbjct: 65 ---------------LYRFSFDRDLLQDGTWKTTYITQPEILEYLESVVDRFDLRRHFRF 109 Query: 490 LLDVVSEWRKDKTQLQDVPLGE 511 +V S + L +V + Sbjct: 110 GTEVTSAIYLEDENLWEVSTDK 131 >6BZ0-A nrPDB Length = 480 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 46/286 (16%), Positives = 94/286 (32%), Gaps = 35/286 (12%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK-----DRIGGRVWDDKSFKGVTVGRGAQ 437 +++IG GP G AA + G KV +E + +GG + + + Sbjct: 8 FDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSH 67 Query: 438 IVNGCINNPVALMCE--QLGISMHKFGERCD------------LIQEGGRITDPTIDKRM 483 +++ ++ + K R D L++ G K + Sbjct: 68 RYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLL 127 Query: 484 DFHFNALLDVVSEWRK---------DKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQ 534 + E + + ++P+ ++I + F E+ + Sbjct: 128 AGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTG--ALNFPEVPKR 185 Query: 535 VLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQL 594 + + GS ++ A A L+ Y I+ K +GLDI++ Sbjct: 186 LGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTK--QGLDIRI 243 Query: 595 KSPVQCIDYSGDEVQVTTT---DGTGYSAQKVLVTVPLALLQKGAI 637 + V + +G EV V T + + K++V V +G + Sbjct: 244 GAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLL 289 Score = 33.2 bits (74), Expect = 0.41, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 16/34 (47%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 K + +IGAG GL G +V V EA D Sbjct: 183 PKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMD 216 >5TUK-A nrPDB Length = 408 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 37/110 (33%), Gaps = 9/110 (8%) Query: 375 LLPKDYHNKSVI----IIGAGPAGLAAARQLHNFGIKVTVLE--AKDRIGGRVWDDKSFK 428 L+P+ H +I +IGAG AG A L FG ++E A R GG D + Sbjct: 14 LVPRGSHMMPIINKILVIGAGIAGPAVCYWLRRFGFSPILVERCANLRKGGHAVDIRGVA 73 Query: 429 GVTVGRGAQIVNGCINNPVALMCEQLGIS---MHKFGERCDLIQEGGRIT 475 C + + +H+ +EG I Sbjct: 74 IDLAKSMGIYKKICNMRTQVELGRYVDAEGNILHEEKGERFGFREGDDIE 123 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 34/110 (30%), Gaps = 5/110 (4%) Query: 528 FSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLA 587 + ++ Q L A G+ LH+ F + D +L I+ Sbjct: 83 YKKICNMRTQVELGRYVDAEGNILHEEKGE-----RFGFREGDDIEILRGDLVQILIDAM 137 Query: 588 EGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAI 637 + V+ I ++V+V DG V+ L + + Sbjct: 138 GDVPCHFNQWVESIKQRDNDVEVQFKDGRTELYDLVIGADGLHSTTRRMV 187 >1LVL-A nrPDB Length = 458 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 37/91 (40%), Gaps = 18/91 (19%) Query: 369 VGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFK 428 V + L + ++++G G GL G +V+V+EA++RI Sbjct: 158 VISSTEALAPKALPQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERI----------- 206 Query: 429 GVTVGRGAQIVNGCINNPVALMCEQLGISMH 459 + + PVA ++LGI++H Sbjct: 207 -------LPTYDSELTAPVAESLKKLGIALH 230 >4ZN0-A nrPDB Length = 311 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 9/82 (10%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD---DKSFKGVTVGRGA 436 +IIIG GPAGL A +G+ +LE ++ I G++ +++ G G Sbjct: 5 ASMYDLIIIGGGPAGLTAGIYAVRYGLDTLILE-RNEISGQISMADIVENYPGFPSISGL 63 Query: 437 QIVNGCINNPVALMCEQLGISM 458 ++ +++G+ Sbjct: 64 EL-----MERFRTHAQEVGVKT 80 >5Z70-A nrPDB Length = 605 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 38/244 (15%), Positives = 75/244 (30%), Gaps = 24/244 (9%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGI----KVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQ 437 + IIG+G AGLA+A L G +T+L+A GG + + + + RG + Sbjct: 4 GRKAWIIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSLDGSGNAEDGYLIRGGR 63 Query: 438 IVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEW 497 +N ++ L + + D + R+ + D + Sbjct: 64 EMNWNYDHFWDLFQDIPALEYPSPYSVLDEYRAVNDNDPNWSKSRLMHKQGQIRDFSTLG 123 Query: 498 RKDKTQLQDVPLGEKIEEIYKAFIKESGIQ---FSELEGQVLQFHLSNLEYACGSNLHQV 554 Q E I+ + K I + F N + Sbjct: 124 LSSAHQW------ELIKLLLKRKEDLDDITIEQYFSDSFLETNFWYLWRSMFAFQNWQSL 177 Query: 555 SARSWDHNEFFAQFAG---DHTLLTPGYSV--------IIEKLAEGLDIQLKSPVQCIDY 603 + F G L+ P Y+ + +G++++ + V +D Sbjct: 178 LEVKLYMHRFLDAIDGLTDMSALVFPKYNQYDSFVVPLVNYLKGQGVNVEFGTRVYDLDM 237 Query: 604 SGDE 607 + + Sbjct: 238 TDNN 241 >5L46-A nrPDB Length = 841 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 32/197 (16%), Positives = 53/197 (26%), Gaps = 22/197 (11%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIK-VTVLEAKDRIGGRVWDDKSFKGVTVGRGAQI 438 +IIG G G++ A L G+K V +LE + G W Sbjct: 20 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLT--------TY 71 Query: 439 VNGCINNPVALMCE-QLGISMHKFGERCDLIQEGGRITDPTIDKRMD-----------FH 486 + IN +L + + + + G I T R+D Sbjct: 72 FHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 131 Query: 487 FNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYA 546 L + ++ L + + I + + G L Sbjct: 132 TEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAP 191 Query: 547 CGSNLHQVSARSWDHNE 563 S L S +WD Sbjct: 192 VTS-LKARSDGTWDVET 207 >2GV8-A nrPDB Length = 447 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 3/46 (6%) Query: 383 KSVIIIGAGPAGLAAARQL--HNFGIKVTVLEAKDRIGGRVWDDKS 426 + + IIGAGP+GL A+ L +VT+ E + GG VW+ S Sbjct: 7 RKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGG-VWNYTS 51 >3RP7-A nrPDB Length = 407 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 17/33 (51%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEA 413 H K I+IGAG GL+AA L GI V EA Sbjct: 23 HMK-AIVIGAGIGGLSAAVALKQSGIDCDVYEA 54 Score = 34.4 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 33/187 (17%), Positives = 59/187 (31%), Gaps = 35/187 (18%) Query: 456 ISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEE 515 +++ + G CD+ + I + +S W + + +G+ +E Sbjct: 40 VALKQSGIDCDVYEAVKEIK-------------PVGAAISVWPNGVKCMAHLGMGDIMET 86 Query: 516 IYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLL 575 + + F E + QF L+ L GS VS R+ E + D Sbjct: 87 FGGPLRRMAYRDFRSGE-NMTQFSLAPLIERTGSRPCPVS-RAELQREMLDYWGRD---- 140 Query: 576 TPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLA-LLQK 634 +Q V + D V V TDG+ S ++ L+ Sbjct: 141 ---------------SVQFGKRVTRCEEDADGVTVWFTDGSSASGDLLIAADGSHSALRP 185 Query: 635 GAIQFNP 641 + F P Sbjct: 186 WVLGFTP 192 >1DXL-A nrPDB Length = 470 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 46/270 (17%), Positives = 90/270 (33%), Gaps = 28/270 (10%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 V+IIG GP G AA + G K T +E + +GG + + + + + Sbjct: 8 DVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAK 67 Query: 444 N----------NPVALMCEQLGISMHKFGERCD----LIQEGGRITDPTIDKRMDFHFNA 489 + N + +G L ++ K + + Sbjct: 68 HSFANHGVKVSNVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVKGYGKFVSPSEIS 127 Query: 490 LLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGI-------QFSELEGQVLQFHLSN 542 + + E K + + G ++ + I E I SE+ +++ Sbjct: 128 VDTIEGENTVVKGKHIIIATGSDVKSLPGVTIDEKKIVSSTGALALSEIPKKLVVIGAGY 187 Query: 543 LEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCID 602 + GS ++ + + + +EK +G+ +LK+ V +D Sbjct: 188 IGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEK--QGMKFKLKTKVVGVD 245 Query: 603 YSGDEVQVTTT-----DGTGYSAQKVLVTV 627 SGD V++T + T A VLV+ Sbjct: 246 TSGDGVKLTVEPSAGGEQTIIEADVVLVSA 275 Score = 32.8 bits (73), Expect = 0.66, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 20/45 (44%) Query: 368 SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 + + L K +++IGAG GL G +VTV+E Sbjct: 163 KIVSSTGALALSEIPKKLVVIGAGYIGLEMGSVWGRIGSEVTVVE 207 >4RG3-A nrPDB Length = 548 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 52/154 (33%), Gaps = 35/154 (22%) Query: 368 SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQL-HNFGIKVTVLEAKDRIGGRVWDDKS 426 S+ A ++ + H ++IGAG G+ A +L H G+ + D GG W Sbjct: 2 SLEASMHMTAQTTHTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGG-TWYWNR 60 Query: 427 FKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEG----GRITDPTI--- 479 + G + +++F DL+QE IT P I Sbjct: 61 YPGALSDTESH--------------------LYRFSFDRDLLQESTWKTTYITQPEILEY 100 Query: 480 ------DKRMDFHFNALLDVVSEWRKDKTQLQDV 507 + HF +V S D L +V Sbjct: 101 LEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEV 134 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 27/67 (40%), Gaps = 7/67 (10%) Query: 580 SVIIEKLAEGLDIQLKSPVQCIDYSGDEVQ--VTTTDGTGYSAQKVLVTVPLALLQKGAI 637 ++++ + + V Y DE VTT G Y A+ V+ V LL AI Sbjct: 102 EDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAV--GLLS--AI 157 Query: 638 QFNPPLS 644 F P L Sbjct: 158 NF-PNLP 163 >6CMZ-A nrPDB Length = 466 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 K ++++GAG GL G+ V+V+EA +R+ Sbjct: 178 PKRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERV 213 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 386 IIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 ++IG GP G AA + GI ++E +DR+GG Sbjct: 12 LVIGGGPGGYVAAIRAGQLGIPTVLVE-RDRLGG 44 >4K2X-A nrPDB Length = 523 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 375 LLPKDYHNK-SVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 L+P+ H + V+I GAGP GL A +L G + VLE Sbjct: 14 LVPRGSHMRYDVVIAGAGPTGLMLACELRLAGARTLVLE 52 >3T14-A nrPDB Length = 437 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 51/168 (30%), Gaps = 10/168 (5%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNF---GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGA 436 + V+I+GAG G+ AA ++ G +VT++ A D + VG G Sbjct: 2 RGSAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISAND------YFQFVPSNPWVGVGW 55 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSE 496 + + I P+ E+ GI + D+ A ++ Sbjct: 56 KERDD-IAFPIRHYVERKGIHFIAQSAEQIDAEAQNITLADGNTVHYDYLMIATGPKLAF 114 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLE 544 + + P+ + G ++ ++ Sbjct: 115 ENVPGSDPHEGPVQSIATVDHAERAFAEYQALLREPGPIVIGAMAGAS 162 >5KOX-A nrPDB Length = 476 Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 19/38 (50%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 H VII G GP GL A +L G++ VLE + Sbjct: 2 SHMIDVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTP 39 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 24/63 (38%) Query: 589 GLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKM 648 G +I+ V +D D V DGT A+ ++ + + + P ++ Sbjct: 116 GAEIRRGCEVAGLDQDADGVTAELADGTRLRARYLVGCDGGRSTVRRLLGVDFPGEPTRV 175 Query: 649 KAI 651 + + Sbjct: 176 ETL 178 >5W4C-A nrPDB Length = 371 Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEA----KDRIGGR---VWDDKSFK 428 + K H+K V+IIG+GP G AA L ++ + E GG+ D ++F Sbjct: 25 VSKKMHSK-VVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLTTTTDVENFP 83 Query: 429 GVTVGRGAQIVNGCINNPVALMCEQLGISM 458 G G + + E+ G + Sbjct: 84 GFPEGVTGT----EMMDKFRAQSERFGTKI 109 >4K22-A nrPDB Length = 365 Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 14/31 (45%), Positives = 18/31 (58%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 V I+G G GLA A L G++V VLE + Sbjct: 5 DVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >6J0Z-C nrPDB Length = 491 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 23/34 (67%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 ++++ V+++GAGP GL A +L G+ V VL+ Sbjct: 2 EFYDSDVVVVGAGPTGLMLAGELRLAGVSVVVLD 35 >2RGJ-A nrPDB Length = 402 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 6/78 (7%) Query: 384 SVIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDR-----IGGRVWDDKSFKGVTVGRGAQ 437 ++I GAG GL+ A LH GI KVT+LE+ +G + +G G Sbjct: 6 DILIAGAGIGGLSCALALHQAGIGKVTLLESSSEIRPLGVGINIQPAAVEALAELGLGPA 65 Query: 438 IVNGCINNPVALMCEQLG 455 + I +Q G Sbjct: 66 LAATAIPTHELRYIDQSG 83 >3CP8-A nrPDB Length = 641 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 66/452 (14%), Positives = 129/452 (28%), Gaps = 61/452 (13%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 L+P+ H VI++GAG AG AA + G+ ++ + R+ Sbjct: 14 LVPRGSHMYDVIVVGAGHAGCEAALAVARGGLHCLLITSDLSAVARM-------SCNPAI 66 Query: 435 GAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVV 494 G + G I + + ++G ++ G + ++ R P + A D Sbjct: 67 GG-VAKGQITREIDALGGEMGKAIDATGIQFRML---NRSKGPAM-----HSPRAQADKT 117 Query: 495 SEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQV 554 + ++ P + +++ SG S ACG+ L+ + Sbjct: 118 QYSLYMRRIVEHEPNIDLLQDTVIGVSANSGKFSSVTVRSGRAIQAKAAILACGTFLNGL 177 Query: 555 SARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTD 614 DH F + + + ++ +P + S D VT Sbjct: 178 IHIGMDH--FPGGRSTAEPPVEGLTESLASLGFSFGRLKTGTPPRIDSRSVDYTIVTEQP 235 Query: 615 GTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAG----IIEKIALQFPYRF 670 G + ++ + + + +K I G K+ P Sbjct: 236 GDVDPVPFSFSST--SVANRNLVSCYLTKTTEKTHDILRTGFDRSPLFTGKVQGVGPRYC 293 Query: 671 WDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVL 730 + + + F P S +F D + + S E + Sbjct: 294 PSIEDKISRF-----PDKSSHHIFLEPEGTDTVEMYVNGFSTSLPEDIQ----------- 337 Query: 731 QQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTV 790 +A LR + +E + Y F + + Sbjct: 338 ---IAGLRSIPGLEEAKMIRPGYAIE----------YDFFHPWQIR---STMETRPVENL 381 Query: 791 FFAGEATNRHFPQTVTGA---YLSGVREASKI 819 FFAG+ A ++G+ KI Sbjct: 382 FFAGQ--INGTSGYEEAAAQGLMAGINAVRKI 411 >5YGQ-A nrPDB Length = 342 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG-C 442 V+I+GAGP GL A +L +K +++ D++GG+ + K + G +V G Sbjct: 8 DVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIYDIPGIPMVTGHG 67 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTID 480 + + + + H ++++ +I DP Sbjct: 68 LTEALMEQIKPFNPTFH----LSEMVENVEKIGDPGFR 101 >6BPY-A nrPDB Length = 374 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 42/118 (35%), Gaps = 19/118 (16%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEA----KDRIGGRVWDDK---SFKGVTVGRGA 436 V+IIG+GPA AA L +K + E GG++ +F G G G Sbjct: 6 KVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFPDGIGG 65 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVV 494 A + E + +FG + + R+ + ++ +N D Sbjct: 66 -----------AELMENMRKQSIRFGTEV-ITETISRVDLSSKPFKLWTEWNDGPDKE 111 Score = 33.2 bits (74), Expect = 0.42, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 20/36 (55%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 NK + +IG G + A L +G VTVL +D++ Sbjct: 158 NKPLYVIGGGDSAAEEAMFLAKYGSSVTVLVRRDKL 193 >2R9Z-A nrPDB Length = 463 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 17/36 (47%), Positives = 23/36 (63%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 K V IIGAG G+ A L +FG +VTV+ +DR+ Sbjct: 166 PKRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRL 201 >5Y77-A nrPDB Length = 473 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 56/171 (32%), Gaps = 33/171 (19%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI----GGR------VWDDKSFKGV 430 + + V IIGAG AG AR L G +V + E + G R ++ + Sbjct: 7 NARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHAL 66 Query: 431 TVG-------------RGAQIVNGCINNPVALMCEQLGISMHKFGER--CDLIQEGGRIT 475 + RG + + + ++ +G Sbjct: 67 RLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAA 126 Query: 476 DPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGI 526 +I HFN LD V R + L +V GE++E+ + I G Sbjct: 127 GASI------HFNLGLDSVDFAR-QRLTLSNVS-GERLEKRFHLLIGADGC 169 >4EMJ-A nrPDB Length = 410 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 9/65 (13%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD---------RIGGRVWDDKSFKGVTVGR 434 ++I+G G G A G+ VT+LEA D RIG + + GV V Sbjct: 145 RLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAWLRGLLTELGVQVEL 204 Query: 435 GAQIV 439 G +V Sbjct: 205 GTGVV 209 >6BZ5-A nrPDB Length = 450 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 26/85 (30%), Gaps = 1/85 (1%) Query: 540 LSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQ 599 S + S S+ ++ L EG+ Q Sbjct: 92 TSEPWEDVWFEWRRGSDASYLGATIAPGVGQSSVHRADFIDALVTHLPEGI-AQFGKRAT 150 Query: 600 CIDYSGDEVQVTTTDGTGYSAQKVL 624 ++ G EVQV TDGT Y ++ Sbjct: 151 QVEQQGGEVQVLFTDGTEYRCDLLI 175 >5TUM-A nrPDB Length = 410 Score = 38.6 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 41/110 (37%), Gaps = 9/110 (8%) Query: 375 LLPKDYHNKS----VIIIGAGPAGLAAARQLHNFGIKVTVLE--AKDRIGGRVWDDKSFK 428 L+P+ H S +++IGAG AG A L FG ++E A R GG+ D + Sbjct: 14 LVPRGSHMMSKNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGIA 73 Query: 429 ---GVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRIT 475 +G QI + G +H+ ++ + Sbjct: 74 THIAREMGIYDQICEMRTRIERGRFVDSSGKVLHEEQGEKFGFRQDDEVE 123 >4TXK-A nrPDB Length = 615 Score = 38.6 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 23/43 (53%) Query: 372 DQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 Y + N +++GAGP GL AA +L G +V ++E + Sbjct: 74 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLVEKR 116 >2BRY-A nrPDB Length = 497 Score = 38.6 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 23/43 (53%) Query: 372 DQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK 414 Y + N +++GAGP GL AA +L G +V ++E + Sbjct: 82 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLVEKR 124 >4N9X-A nrPDB Length = 411 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 39/100 (39%), Gaps = 11/100 (11%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG 441 + V+I G G GLA A L G+++ VLE ++ + T+G+G + Sbjct: 3 SFDVVIAGGGMVGLALACGLQGSGLRIAVLE-----------KQAAEPQTLGKGHALRVS 51 Query: 442 CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDK 481 IN + +G+ + +R + + K Sbjct: 52 AINAASECLLRHIGVWENLVAQRVSPYNDMQVWDKDSFGK 91 >3COX-A nrPDB Length = 507 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 5/49 (10%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTV 432 ++IG+G G AA +L GI ++E GR WD G Sbjct: 13 PALVIGSGYGGAVAALRLTQAGIPTQIVEM-----GRSWDTPGSDGKIF 56 >3AB1-A nrPDB Length = 360 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 41/263 (15%), Positives = 91/263 (34%), Gaps = 25/263 (9%) Query: 378 KDYHN-KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGA 436 D+H+ + + IIG GP G+ AA Q I ++E+ ++GG++ K + Sbjct: 9 TDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYD---- 64 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGER---CDLIQEGGRITDPTIDKRM-DFHFNALLD 492 V G P + E L ++ + + + ++ D T + R + Sbjct: 65 --VAGFPEVPAIDLVESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRSRA 122 Query: 493 VVSEWRKDKTQLQDVPLGEKIEEIYKA---FIKESGIQFSELEGQVLQFHLSNLEYACGS 549 V+ + + +P I+ + + + +S F ++ S L++ G Sbjct: 123 VLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVEDFKGKRVVIVGGGDSALDWTVGL 182 Query: 550 NLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQ 609 + S F + + +D+ L++ V I+ S + Sbjct: 183 IKNAASVTLVHRGHEFQGHGKTAHEVERA------RANGTIDVYLETEVASIEESNGVLT 236 Query: 610 VTTTDGT-----GYSAQKVLVTV 627 + A ++L+ + Sbjct: 237 RVHLRSSDGSKWTVEADRLLILI 259 >3G5Q-A nrPDB Length = 443 Score = 37.8 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 45/126 (35%), Gaps = 16/126 (12%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFK-----GVTVGRGA 436 + V ++GAG AG AA L G+ V + E + + R+ + G Sbjct: 1 MERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPK---RMTPAHGTDRFAEIVCSNSLGG 57 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPT-----IDKRMDFHFNALL 491 + A M + G + + + + G D I +R+ H LL Sbjct: 58 EGETNAKGLLQAEM-RRAGSLVMEAADLARVPAGGALAVDREEFSGYITERLTGH--PLL 114 Query: 492 DVVSEW 497 +VV E Sbjct: 115 EVVREE 120 >4JDR-A nrPDB Length = 474 Score = 37.8 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 25/36 (69%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 V+++GAGPAG +AA + + G++ ++E + +GG Sbjct: 8 QVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGG 43 >3ISH-A nrPDB Length = 311 Score = 37.8 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 46/112 (41%), Gaps = 10/112 (8%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW---DDKSFKGVTVGRGAQIVN 440 IIG GPAGL+A G+K VL K GG++ + +++ GV ++V+ Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVK-----EVVS 57 Query: 441 GC-INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALL 491 G P C + G+ H+ + ++ D + + ++ Sbjct: 58 GLDFMQPWQEQCFRFGLK-HEMTAVQRVSKKDSHFVILAEDGKTFEAKSVII 108 >3LZX-A nrPDB Length = 332 Score = 37.8 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 67/190 (35%), Gaps = 13/190 (6%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRG 435 + +D + IIG GP GL A V ++E+ ++GG+ + + Sbjct: 1 MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQ------LSALYPEKY 54 Query: 436 AQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRIT--DPTIDKRM---DFHFNAL 490 V G + L M KF + L Q + + K + + H++ Sbjct: 55 IYDVAGFPKIRAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVTNEETHYSKT 114 Query: 491 LDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSN 550 + + + K + ++ E+ E + + +F+ +L S +++A Sbjct: 115 VIITAGNGAFKPRKLELENAEQYEGKNLHYFVDDLQKFAGRRVAILGGGDSAVDWALMLE 174 Query: 551 L--HQVSARS 558 +VS Sbjct: 175 PIAKEVSIIH 184 >3DDM-A nrPDB Length = 392 Score = 37.8 bits (86), Expect = 0.021, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 45/158 (28%), Gaps = 15/158 (9%) Query: 402 HNFGIKVTVLE-AKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHK 460 G+ + + + A R G +W G +G A +N V G K Sbjct: 116 AIAGLDIALCDLAARRAGQPLWAWLGGSGDRIGVYASGINPENPEDVVARKAAEGYRAFK 175 Query: 461 FGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAF 520 D D R H LL + D Q D+P ++ Sbjct: 176 LKVGFD----------DARDVRNALHVRELLGAATPLMADANQGWDLPRARQM----AQR 221 Query: 521 IKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARS 558 + + + + E + + E A + + + Sbjct: 222 LGPAQLDWLEEPLRADRPAAEWAELAQAAPMPLAGGEN 259 >2DCE-A nrPDB Length = 111 Score = 37.8 bits (86), Expect = 0.021, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 10/84 (11%) Query: 287 DVMELDELYEFPEYSRD-----PTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLV 341 ++++ +E PE+ P YL +RN IL W E P+ + GL Sbjct: 25 NIIQEEEKQAIPEFFEGRQAKTPERYLKIRNYILDQW-----EICKPKYLNKTSVRPGLK 79 Query: 342 RIRCVQEVERILYFMTRKGLINTG 365 V + RI ++ G IN G Sbjct: 80 NCGDVNCIGRIHTYLELIGAINFG 103 >6DLL-A nrPDB Length = 398 Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAK--DRIGGRVWDDKSFKG 429 V IIGAGP+GL + LH GI ++E + + + GR+ +G Sbjct: 7 QVAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQG 54 >5XGV-A nrPDB Length = 462 Score = 37.5 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 17/33 (51%) Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 VII G GP GL A +L G+ VLE D Sbjct: 4 VIIAGGGPVGLMLACELGLAGVDTVVLERHDAP 36 Score = 36.3 bits (82), Expect = 0.058, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 24/63 (38%), Gaps = 5/63 (7%) Query: 569 AGDHTLLTPGYSVIIEKLAE-----GLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKV 623 ++ + +L E G+ ++ + + + + D VQVTT DG + Sbjct: 86 GDRAFSFAVPHAQVERRLEERARSLGVRVRRSTEITSVRQTPDGVQVTTGDGEVVEGAYL 145 Query: 624 LVT 626 + Sbjct: 146 VGC 148 >2GAG-B nrPDB Length = 405 Score = 37.5 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 2/60 (3%) Query: 377 PKDYHNKSVIIIGAGPAGLAAARQLHN-FGI-KVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 P+ + II+G G GLA A L GI V VLE GG + + + Sbjct: 16 PEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 75 >2VOU-A nrPDB Length = 397 Score = 37.1 bits (84), Expect = 0.030, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 + ++G +GL AA L + G+ V V E + Sbjct: 7 RIAVVGGSISGLTAALMLRDAGVDVDVYERSPQP 40 >5UWY-A nrPDB Length = 308 Score = 37.1 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG-RVWDDKSFKGVTVG 433 ++ ++++G G + + A L F KVTV+ +D++ ++ D++F V Sbjct: 143 DQDLLVVGGGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKILQDRAFANDKVD 195 Score = 36.3 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 7/104 (6%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR---VWDDKSFKGVTVGRGAQI 438 +IIG+GPAG+ AA + V ++E GG+ +D +++ G G ++ Sbjct: 4 MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGA-PGGQMNNTFDIENYPGYDHISGPEL 62 Query: 439 VNGCINNPV-ALMCEQLGI--SMHKFGERCDLIQEGGRITDPTI 479 + GI + FG+ ++ E T+ Sbjct: 63 AMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKTV 106 >6C6P-A nrPDB Length = 458 Score = 37.1 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 49/151 (32%), Gaps = 24/151 (15%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 ++ VII+GAG G A A L G KVTV+E + K G + Sbjct: 5 QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE------------RDLKEPDRIVGEFLQ 52 Query: 440 NGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRK 499 G + + + LG+ G ++ G I D + Sbjct: 53 PGGYH-----VLKDLGLGDTVEGLDAQVV-NGYMIHDQESKSEVQIP------YPLSENN 100 Query: 500 DKTQLQDVPLGEKIEEIYKAFIKESGIQFSE 530 + G I + KA + E +F E Sbjct: 101 QVQSGRAFHHGRFIMSLRKAAMAEPNAKFIE 131 >5VT6-A nrPDB Length = 269 Score = 37.1 bits (84), Expect = 0.033, Method: Composition-based stats. Identities = 30/120 (25%), Positives = 45/120 (37%), Gaps = 12/120 (10%) Query: 377 PKDYHNKSVIIIGAGPAGLAAA--RQLHNFGIKVTV--LEAKDRIGGRVWDDKSFKGVTV 432 P K V + G GL AA R+LH+ G+ V V E D + + ++ G Sbjct: 19 PGSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERD-AGRDF 77 Query: 433 GRGAQIVNGCINNPVALMCEQLGIS-MHKFGERCDLIQEGGRITDPTIDKRMDFHFNALL 491 A V CE+ + FG+ LI G D T K ++A++ Sbjct: 78 KAYAVDVAD------FESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVM 131 >2E5V-A nrPDB Length = 472 Score = 37.1 bits (84), Expect = 0.036, Method: Composition-based stats. Identities = 39/243 (16%), Positives = 76/243 (31%), Gaps = 34/243 (13%) Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNP 446 IIG+G AGL+A L G KVT++ + GG K G A + + Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLISKRID-GGSTPIAKG------GVAASVGSDDSPEL 56 Query: 447 VALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQD 506 A ++G + + E + ++ W + + Sbjct: 57 HAQDTIRVGDGLCDVKTVNYVTSEAKNV----------------IETFESWGFEFEEDLR 100 Query: 507 VPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFA 566 + G + + F+ L + + +E + + E Sbjct: 101 LEGGHTKRRVLHRTDETGREIFNFLLKLAREEGIPIIEDRLVEIRVKDGKVTGFVTEKRG 160 Query: 567 QFAGDHTLL--TPGYSVIIEK-------LAEGLDIQL--KSPVQCIDYSGDEVQVTTTDG 615 L+ T GYS + E + +G+ I + + +++ VT+ DG Sbjct: 161 LVEDVDKLVLATGGYSYLYEYSSTQSTNIGDGMAIAFKAGTILADMEFVQFHPTVTSLDG 220 Query: 616 TGY 618 + Sbjct: 221 EVF 223 >5XHU-A nrPDB Length = 329 Score = 36.7 bits (83), Expect = 0.037, Method: Composition-based stats. Identities = 29/196 (14%), Positives = 53/196 (27%), Gaps = 5/196 (2%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 V IIG GP GL A +K V+E ++GG+V K + G + G Sbjct: 4 DVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIRDIGGIPGIAGKQ 63 Query: 444 NNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRK-DKT 502 +R + T H+ + + + Sbjct: 64 LIEQLKEQAATFDPDIVLNQRVTGFERLDDGTIVLTGSEGKKHYTRTVILACGMGTLEVN 123 Query: 503 QLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHN 562 + + + E F + + +++A S Sbjct: 124 EFDSEDAARYAGKNLH-YGVEKLDAFKGKRVVISGGGDTAVDWANELEPIAASVTVVHRR 182 Query: 563 EFFAQFAGDHTLLTPG 578 E +F G + +T Sbjct: 183 E---EFGGMESSVTKM 195 >1ZDL-A nrPDB Length = 517 Score = 36.7 bits (83), Expect = 0.038, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 48/131 (36%), Gaps = 21/131 (16%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVN- 440 + +++IG G GLA A++ G KV V + + + S +G G G VN Sbjct: 32 SFDLLVIGGGSGGLACAKEAAQLGKKVAVAD---------YVEPSPRGTKWGLGGTCVNV 82 Query: 441 GCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKD 500 GCI + LG G D G + P + ++ + + V K Sbjct: 83 GCIPKKLMHQAALLG------GMIRDAHHYGWEVAQP-----VQHNWKTMAEAVQNHVKS 131 Query: 501 KTQLQDVPLGE 511 V L + Sbjct: 132 LNWGHRVQLQD 142 >1C0L-A nrPDB Length = 363 Score = 36.7 bits (83), Expect = 0.039, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 K V+++G+G GL++A L G V +L A+D Sbjct: 7 KRVVVLGSGVIGLSSALILARKGYSVHIL-ARD 38 >5U8W-A nrPDB Length = 481 Score = 36.7 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 16/41 (39%), Positives = 20/41 (48%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDR 416 L K + +IGAG GL G +VTVLEA D+ Sbjct: 178 LEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDK 218 Score = 35.1 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 50/277 (18%), Positives = 92/277 (33%), Gaps = 36/277 (12%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVL------EAKDRIGG----------RVWDDKS 426 V++IGAGP G AA + G+K + E K +GG + D S Sbjct: 8 FDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSS 67 Query: 427 FK----GVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKR 482 +K G + A++ + I + G L + G + K Sbjct: 68 YKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKL 127 Query: 483 MDFH---------FNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEG 533 + +L+ + ++ ++P ++I Q + Sbjct: 128 LANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKL 187 Query: 534 QVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQ 593 V+ + LE GS ++ A + ++ K +GL+I+ Sbjct: 188 GVIGAGVIGLE--LGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTK--QGLNIR 243 Query: 594 LKSPVQCIDYSGDEVQVTTTDGTG---YSAQKVLVTV 627 L + V + +V VT TD G + K++V V Sbjct: 244 LGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAV 280 >5X6R-A nrPDB Length = 420 Score = 36.7 bits (83), Expect = 0.041, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 27/58 (46%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 ++SV IIGAG G AA G VT+ + + +K+ K + + A+ + Sbjct: 28 SESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGI 85 >3NTA-A nrPDB Length = 574 Score = 36.7 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 + + ++G G GL LH+ GIK T+LE D++ Sbjct: 150 NVEHATVVGGGFIGLEMMESLHHLGIKTTLLELADQV 186 >3NIX-A nrPDB Length = 421 Score = 36.7 bits (83), Expect = 0.044, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 20/29 (68%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 V++IGAGPAG AA ++ G KV ++E Sbjct: 7 DVLVIGAGPAGTVAASLVNKSGFKVKIVE 35 >6GAR-A nrPDB Length = 349 Score = 36.7 bits (83), Expect = 0.046, Method: Composition-based stats. Identities = 32/242 (13%), Positives = 75/242 (30%), Gaps = 21/242 (8%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 V +IG GPAGL +A ++ ++E +GG++ K + G + Sbjct: 7 FDVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPHLGGKI-HVYPEKMIW-DVGG--LLPV 62 Query: 443 INNPVALMCEQLGISMHKF-----GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEW 497 + + Q G++ + + G T T + HF+ + V + Sbjct: 63 TGDKLIEQLVQQGLTFKPEVVLDTKVESIIRNQDGTFTLKTST--GEEHFSKTVIVATGS 120 Query: 498 RKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSAR 557 K Q + E+ E + +S +F + S +++A Sbjct: 121 GILKPQKLSIEGAERFEVSNLNYTVKSLKRFKGKTVIISGGGNSAVDWANELEP------ 174 Query: 558 SWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTG 617 L+ + + + + + + + + + + + T Sbjct: 175 ----IAKKVYVTYRKEELSGHEAQVKQLMNSSAECFFNTSITKLIAGDNHEAIEYVELTN 230 Query: 618 YS 619 + Sbjct: 231 HE 232 >2BC1-A nrPDB Length = 490 Score = 36.7 bits (83), Expect = 0.047, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 22/50 (44%) Query: 366 VLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 + AD ++ K V ++GAG G+ A G +V +++ D Sbjct: 178 LYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVD 227 >5TUF-A nrPDB Length = 409 Score = 36.7 bits (83), Expect = 0.048, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 33/90 (36%), Gaps = 5/90 (5%) Query: 548 GSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDE 607 G+ LH+ F + + +L I+ K + + K V I+ + D Sbjct: 103 GNVLHEEQGE-----TFGFRQDDEVEILRGDLVEILMKAIADIPCEFKQSVIKIEQNEDS 157 Query: 608 VQVTTTDGTGYSAQKVLVTVPLALLQKGAI 637 V VT DG + V+ + +G + Sbjct: 158 VTVTYKDGRVENYDLVIAADGIHSATRGMV 187 >3GMC-A nrPDB Length = 415 Score = 36.3 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 27/72 (37%), Gaps = 5/72 (6%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI---GGRVWDDKSFKGVTVGRGA--Q 437 + + G G AGL AA L G V + E + G ++ + V G GA Sbjct: 48 RRAEVAGGGFAGLTAAIALKQNGWDVRLHEKSSELRAFGAGIYLWHNGLRVLEGLGALDD 107 Query: 438 IVNGCINNPVAL 449 ++ G P Sbjct: 108 VLQGSHTPPTYE 119 >3D8X-A nrPDB Length = 326 Score = 35.9 bits (81), Expect = 0.066, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 42/119 (35%), Gaps = 19/119 (15%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEA----KDRIGGR---VWDDKSFKGVTVGRGA 436 V IIG+GPA AA L IK + E GG+ + ++F G G Sbjct: 12 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 71 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS 495 + + + + G + + + ++ + ++ FN + V+ Sbjct: 72 S----ELMDRMREQSTKFGTEI--------ITETVSKVDLSSKPFKLWTEFNEDAEPVT 118 >6ACQ-A nrPDB Length = 302 Score = 35.9 bits (81), Expect = 0.068, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 54/144 (37%), Gaps = 4/144 (2%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 L+P+ H K V +IGAG G A+ G +V + + KD R D + + + Sbjct: 14 LVPRGSHMKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVK 73 Query: 435 GAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVV 494 +I + + + ++M CDL+ E + I K++ + + Sbjct: 74 KGKIEEATKVEILTRISGTVDLNM---AADCDLVIEA-AVERMDIKKQIFADLDNICKPE 129 Query: 495 SEWRKDKTQLQDVPLGEKIEEIYK 518 + + + L + + K Sbjct: 130 TILASNTSSLSITEVASATKRPDK 153 >1Q1R-A nrPDB Length = 431 Score = 35.9 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 20/42 (47%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 423 + +++IG G GL A + VT+L+ R+ RV Sbjct: 149 DNRLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTA 190 >2EQ6-A nrPDB Length = 464 Score = 35.9 bits (81), Expect = 0.073, Method: Composition-based stats. Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 +I+IG GP G AA + G+KV +EA + +GG Sbjct: 8 DLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGE-VGG 42 >4YKF-A nrPDB Length = 521 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 K V +IG G +G+ AA L VT+LE Sbjct: 355 GKRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 385 >1FL2-A nrPDB Length = 310 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 K V +IG G +G+ AA L VT+LE Sbjct: 144 GKRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 174 >2YVG-A nrPDB Length = 408 Score = 35.9 bits (81), Expect = 0.078, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVW 422 ++I+G G GL A G+ V+++E + R+ R Sbjct: 147 RLLIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAA 185 >6IUM-B nrPDB Length = 701 Score = 35.9 bits (81), Expect = 0.078, Method: Composition-based stats. Identities = 33/127 (25%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 303 DPTMYL-ALRNLILALWYTNCKEALTPQKCIPHIIVR-GLVRIRCVQEVERILYFMT--- 357 +P YL RN + A+ P KC+ + QE E LY +T Sbjct: 208 NPEGYLGFARNTVAAMAKNFP----APLKCLEAVAGSLKPFEQGLKQEREGFLYLVTTPE 263 Query: 358 ----RKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEA 413 R S D + V +IGAG G + N GI VT+LE Sbjct: 264 SRALRHAFFGERAASKIPDVPEGTPTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILET 323 Query: 414 KDRIGGR 420 K R Sbjct: 324 KQEALDR 330 >4JNQ-A nrPDB Length = 345 Score = 35.9 bits (81), Expect = 0.078, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 8/79 (10%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR---VWDDKSFKGVTVGRGAQIV 439 VI+IG+GPAG AA +K V+ A + GG+ D +++ G Sbjct: 27 APVIVIGSGPAGYTAAIYAARAMLKPVVI-AGLQQGGQLMITTDVENYPGYAEPVQGPW- 84 Query: 440 NGCINNPVALMCEQLGISM 458 + +A E +G + Sbjct: 85 ---MMEQMARQAENVGAQI 100 >1FOH-A nrPDB Length = 664 Score = 35.9 bits (81), Expect = 0.080, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 12/84 (14%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 V+I+GAGPAGL AAR L + + K + R+ D +S K + Sbjct: 9 DVLIVGAGPAGLMAARVLSEY------VRQKPDLKVRIIDKRSTKVY------NGQADGL 56 Query: 444 NNPVALMCEQLGISMHKFGERCDL 467 + LG++ E D+ Sbjct: 57 QCRTLESLKNLGLADKILSEANDM 80 >3CGD-A nrPDB Length = 480 Score = 35.5 bits (80), Expect = 0.085, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 17/35 (48%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIG 418 V IIG G GL A G KV ++E D IG Sbjct: 188 DVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIG 222 >1F6M-A nrPDB Length = 320 Score = 35.5 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 41/100 (41%), Gaps = 6/100 (6%) Query: 377 PKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR---VWDDKSFKGVTVG 433 H+K ++I+G+GPAG AA ++ ++ ++ GG+ + +++ G Sbjct: 1 GTTKHSK-LLILGSGPAGYTAAVYAARANLQPVLITGMEK-GGQLTTTTEVENWPGDPND 58 Query: 434 RGAQIVNGCINNPVALMCEQLGIS-MHKFGERCDLIQEGG 472 ++ ++ ++ ++K + + G Sbjct: 59 LTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNG 98 >3O0H-A nrPDB Length = 484 Score = 35.5 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 21/41 (51%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 + + KS++I+G G G+ A H G+K T+L D Sbjct: 184 IFDLEKLPKSIVIVGGGYIGVEFANIFHGLGVKTTLLHRGD 224 >5GSN-A nrPDB Length = 453 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 63/212 (29%), Gaps = 13/212 (6%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIK------VTVLEAKDRIGGRVWDDKSFKGVTVGRGA 436 K V +IGAGP+GLA R + + + E + GG +W+ G+ Sbjct: 3 KRVAVIGAGPSGLAQLRAFQSAADQGAEIPEIVCFEKQANWGG-LWNYTWRTGL--DENG 59 Query: 437 QIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSE 496 + V+ + + + G+ + ++ + DV Sbjct: 60 EPVHCSMYRYLWSNGPKEGLEFADYSFEEHFGKQIASYPPRAVLFDYIEGRVHKADVRKW 119 Query: 497 WRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVL----QFHLSNLEYACGSNLH 552 R + E + A E+ +S V+ F N+ + G + Sbjct: 120 IRFNSPVRWVSYDAETAKFTVTAHNHETDSTYSAAFDHVICASGHFSTPNVPFYEGFDTF 179 Query: 553 QVSARSWDHNEFFAQFAGDHTLLTPGYSVIIE 584 +F G L+ S + Sbjct: 180 NGRIVHAHDFRDAREFEGKDVLVMGASSSAED 211 >4MOP-A nrPDB Length = 633 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKD 415 V+I+G+GP G AR+L G KV + + + Sbjct: 48 DVVIVGSGPIGCTYARELVGAGYKVAMFDIGE 79 >2NVK-X nrPDB Length = 488 Score = 35.1 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 4/52 (7%) Query: 360 GLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVL 411 G + G+ S L D +++GAG GL A L G + TV+ Sbjct: 169 GAVEYGITS----DDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVM 216 >5EZ7-A nrPDB Length = 392 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS--FKGVTVGRGAQI 438 + ++I+G G AGL +L G ++E+ GG+ + G + Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGYATVLVESASLGGGQSVKSQGIIHGGAKYALHGAL 65 >3ICS-A nrPDB Length = 588 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 + + +IG G G+ L GI+VT++E Sbjct: 184 EKKPRHATVIGGGFIGVEMVENLRERGIEVTLVE 217 >4NTC-A nrPDB Length = 335 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKG 429 V+IIGAGPAGL+ A L V ++ + + G Sbjct: 16 DVLIIGAGPAGLSTATGLARQLHTAVVFDSGVYRNAKTQHMHNVLG 61 >6A37-A nrPDB Length = 552 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 40/109 (36%), Gaps = 11/109 (10%) Query: 378 KDYHNKSVIIIGAGPAGLAAARQLH-NFGIKVTVLEAKDRIGGRVWDDKSFKG--VTVGR 434 + IIIGAG GL + ++L +F +KV + +GG W + G Sbjct: 22 TQKMDFDAIIIGAGFGGLYSLKKLRDDFNLKVRAFDRATEVGG-TWFWNQYPGALSDSET 80 Query: 435 GAQIVNGCINNPVALMCEQLGIS-------MHKFGERCDLIQEGGRITD 476 + + ++ IS + + ++ DL ++ T Sbjct: 81 HLYCYSWDKELLQEMEIKRKYISQPDVLAYLKRVADKHDLRKDIQFETG 129 >6AON-A nrPDB Length = 478 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 10/71 (14%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 V++IGAGP G AA + G+ V ++A ++ +G G GC Sbjct: 8 FDVVVIGAGPGGYIAAIRAAQLGMSVACIDA----------WQNGQGGPAPGGTCTNVGC 57 Query: 443 INNPVALMCEQ 453 I + L + Sbjct: 58 IPSKALLQSSE 68 Score = 34.8 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 9/61 (14%) Query: 353 LYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE 412 L F + L N G L++GA K + +IGAG GL G +VT+LE Sbjct: 166 LPFDEKNILSNDGALNIGA---------VPKKLGVIGAGVIGLEMGSVWRRLGAEVTILE 216 Query: 413 A 413 A Sbjct: 217 A 217 >2VHY-A nrPDB Length = 377 Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 327 TPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVI 386 T +P + V R +V T+ G GVL G V+ Sbjct: 122 TADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGG---RGVLMGGVPGV------EPADVV 172 Query: 387 IIGAGPAGLAAARQLHNFGIKVTVLE 412 +IGAG AG AAR + G VTVL+ Sbjct: 173 VIGAGTAGYNAARIANGMGATVTVLD 198 >4USR-A nrPDB Length = 361 Score = 34.8 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 1/65 (1%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR-VWDDKSFKGVTVGRGAQIVNGC 442 VI+IG G A L A L + +L+ + GG + S + + + I Sbjct: 9 DVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGGAWLHAWDSLRLFSPAAWSSIAGWP 68 Query: 443 INNPV 447 + +P Sbjct: 69 MPSPT 73 >3L8K-A nrPDB Length = 466 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 19/36 (52%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 + ++IIGAG GL A G++ ++E DR Sbjct: 172 PQDMVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRA 207 >5ZYN-B nrPDB Length = 471 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 383 KSVIIIGAGPAGLAAARQL-HNFGIKVTVLEAKDRIGG 419 + V++IG+G AGL + +L + I V +L+ IGG Sbjct: 5 QPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGG 42 >1D4E-A nrPDB Length = 572 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 15/135 (11%) Query: 368 SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSF 427 D+ + V+IIG+G AGLAAA + G KV +LE + GG Sbjct: 112 KAAQDKAIAAGVKETTDVVIIGSGGAGLAAAVSARDAGAKVILLEKEPIPGGNT------ 165 Query: 428 KGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHF 487 A +N P A +LGI K D ++ G I DP + K + + Sbjct: 166 -----KLAAGGMNAAETKPQA----KLGIEDKKQIMIDDTMKGGRNINDPELVKVLANNS 216 Query: 488 NALLDVVSEWRKDKT 502 + +D ++ D T Sbjct: 217 SDSIDWLTSMGADMT 231 >2RR4-A nrPDB Length = 69 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 8/53 (15%) Query: 139 WVQCTKPECRKWRQLTKEIQLTPQI-AKTYRCGMKPNTAIKPETSDHCSLPED 190 WVQC+ P C KWR+L I P + + C NT ++ + C +PE+ Sbjct: 18 WVQCSFPNCGKWRRLCGNID--PSVLPDNWSCDQ--NTDVQ---YNRCDIPEE 63 >6DU7-A nrPDB Length = 448 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 +SV I+GAG + A LH FG+K + +DR Sbjct: 166 PESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRP 201 >5X68-A nrPDB Length = 391 Score = 34.0 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 30/88 (34%), Gaps = 11/88 (12%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 442 K V +IG G G A L ++ V EA++ RV + +N Sbjct: 15 KKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDT--RVATFTR---------GRSINLA 63 Query: 443 INNPVALMCEQLGISMHKFGERCDLIQE 470 +++ + +G+ + + Sbjct: 64 LSHRGRQALKAVGLEDQIVSQGIPMRAR 91 >6BWT-A nrPDB Length = 319 Score = 34.0 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 39/114 (34%), Gaps = 16/114 (14%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIV 439 ++ +II+G+GPAG AA +K ++ + GG++ + Sbjct: 5 ANHHKLIILGSGPAGYTAAIYAARANLKPVIITGM-QPGGQLTTTTD-----------VY 52 Query: 440 NGCINNPVALMCEQLGISMHKFGERCD---LIQEGGRITDPTIDKRMDFHFNAL 490 N P +M +L + K ER D + + ++ Sbjct: 53 NWPGE-PDGIMGPELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGEVEQY 105 >3QJ4-A nrPDB Length = 342 Score = 34.0 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 382 NKSVIIIGAGPAG-LAAA--RQLHNFGIKVTVLEAKDRIGGRVWD--DKSFKGVTVGRGA 436 V+I+GAG G L AA R+ + + + V + D GGR+ T GA Sbjct: 1 MAQVLIVGAGMTGSLCAALLRRQTSGPLYLAVWDKADDSGGRMTTACSPHNPQCTADLGA 60 Query: 437 QIVNGCINN 445 Q + C + Sbjct: 61 QYIT-CTPH 68 >3WSV-A nrPDB Length = 322 Score = 34.0 bits (76), Expect = 0.31, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 11/61 (18%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNFGI-KVTVL----------EAKDRIGGRVWDDKSF 427 ++ V+I+G G G + A + N G+ VL EA D + G W +K+ Sbjct: 2 KKTSRKVVIVGTGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNV 61 Query: 428 K 428 Sbjct: 62 S 62 >3IP1-A nrPDB Length = 404 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 17/28 (60%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVL 411 +V+I+G GP GLAA L + G +L Sbjct: 216 NVVILGGGPIGLAAVAILKHAGASKVIL 243 >1GAL-A nrPDB Length = 583 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 9/64 (14%) Query: 377 PKDYHNKSV--IIIGAGPAGLAAARQLHNF-GIKVTVLEAK----DRIGGRVWDDKSFKG 429 PKD ++V II G G GL A +L I V V+E+ DR G + +D + G Sbjct: 12 PKDVSGRTVDYIIAGGGLTGLTTAARLTENPNISVLVIESGSYESDR--GPIIEDLNAYG 69 Query: 430 VTVG 433 G Sbjct: 70 DIFG 73 >1GPJ-A nrPDB Length = 404 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 49/144 (34%), Gaps = 35/144 (24%) Query: 362 INTGVLSVGADQYLLPKDY----HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 I+ G +S+G+ L + H+K+V+++GAG G A+ L + G++ + + Sbjct: 143 ISEGAVSIGSAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVL------V 196 Query: 418 GGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDP 477 R ++ + LG +F E D + + Sbjct: 197 ANRTYE----------------------RAVELARDLGGEAVRFDELVDHLARSDVVVSA 234 Query: 478 TIDKRMDFHFNALLDVVSEWRKDK 501 T + DV RK Sbjct: 235 TA---APHPVIHVDDVREALRKRD 255 >4YNU-A nrPDB Length = 571 Score = 33.6 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Query: 384 SVIIIGAGPAGLAAARQLHNF-GIKVTVLEAK 414 I++G G +GL A +L + V +LEA Sbjct: 7 DYIVVGGGTSGLVVANRLSENPDVSVLLLEAG 38 >2EEZ-A nrPDB Length = 369 Score = 33.6 bits (75), Expect = 0.41, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 8/53 (15%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAK--------DRIGGRVWDDKS 426 SV+I+G G G AA+ G +VT+L+ D GGRV + Sbjct: 166 PASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTA 218 >1KNR-A nrPDB Length = 540 Score = 33.6 bits (75), Expect = 0.41, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Query: 381 HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS 426 H+ V+IIG+G AGL+ A +L + +V VL G + + Sbjct: 7 HSCDVLIIGSGAAGLSLALRLADQ-HQVIVLSKGPVTEGSTFYAQG 51 >4U2L-A nrPDB Length = 510 Score = 33.2 bits (74), Expect = 0.44, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 21/49 (42%), Gaps = 5/49 (10%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTV 432 ++IG G +A +L G++ +LE G++W+ G Sbjct: 7 PAVVIGTGYGAAVSALRLGEAGVQTLMLEM-----GQLWNQPGPDGNIF 50 >2CUL-A nrPDB Length = 232 Score = 33.2 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVL 411 V+I+GAG +G A L G++V +L Sbjct: 5 QVLIVGAGFSGAETAFWLAQKGVRVGLL 32 >4CBQ-A nrPDB Length = 314 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 25/65 (38%), Gaps = 7/65 (10%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE----AKDRIGGRVWDDK---SFKGVTV 432 + V+IIG+GPA AA L +K + E GG++ +F G Sbjct: 2 SNIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPN 61 Query: 433 GRGAQ 437 G Sbjct: 62 GIDGN 66 >5EVY-X nrPDB Length = 438 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 37/300 (12%), Positives = 78/300 (26%), Gaps = 33/300 (11%) Query: 513 IEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDH 572 +E I + I E ++ + S Sbjct: 72 VEAIQRLGIGELYKSVADSTPA------PWQDIWF--EWRHAHDASLVGATVAPGIGQSS 123 Query: 573 TLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALL 632 ++ ++L G+ L V + + V + DG+ Y+A + + Sbjct: 124 IHRADFIDMLEKRLPAGIAS-LGKHVVDYTENAEGVTLNFADGSTYTADVAIAADGIKSS 182 Query: 633 QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSAS--K 690 + + L A++ G L Q A H+ Sbjct: 183 MRNTL-----LRAAGHDAVHPQFTGTSAYRGLVETSAL-REAYQAASLDEHLLNVPQMYL 236 Query: 691 RGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCM--ATLRELFKEQEVPD 748 V + K ++++ ++ +VA + D+ ++ L E Sbjct: 237 IEDGHVLTFPVKKGKLIIIVAFVSDRSVAKPQWPSDQPWVRPATTDEMLHRFAGAGEAVK 296 Query: 749 PTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGA 808 + T + +D + + G V G+A + P GA Sbjct: 297 TLLTSIKS--------------PTLWALHDFDPLPTYVHGRVALIGDAAHAMLPHQGAGA 342 Score = 32.1 bits (71), Expect = 0.95, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 15/42 (35%), Gaps = 1/42 (2%) Query: 378 KDYHNKSVIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIG 418 K V +IG G AG A A L V + E G Sbjct: 18 KSKSPLRVAVIGGGIAGTALALGLSKSSHVNVKLFETAPAFG 59 >3IWA-A nrPDB Length = 472 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 384 SVIIIGAGPAGLAAARQLHNF-GIKVTVLEAKDRI 417 +I+G G GL A L + GI TV+E D+I Sbjct: 161 KAVIVGGGFIGLEMAVSLADMWGIDTTVVELADQI 195 >6GAS-A nrPDB Length = 331 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 43/117 (36%), Gaps = 11/117 (9%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCI 443 + IIG GP GL A V ++E+ ++GG+ + + V G Sbjct: 11 DITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQ------LSALYPEKYIYDVAGFP 64 Query: 444 NNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKD 500 + + L M KF L + T++K+ D F + + + + K Sbjct: 65 KVRAQELVDNLKEQMKKFDPTVCLEEAV-----DTLEKQADGIFKLVTNKQTHYSKS 116 >4H7U-A nrPDB Length = 602 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 43/267 (16%), Positives = 82/267 (30%), Gaps = 33/267 (12%) Query: 367 LSVGADQYLLPKD---YHNKSVIIIGAGPAGLAAARQLHN-FGIKVTVLEAKDRIGGRVW 422 ++ GA Y P D + I+ G G AGL A +L KV V+EA + Sbjct: 22 IARGAITYQHPDDLPSGVDYDFIVAGGGTAGLVVASRLSENSNWKVLVIEAG--PSNKDA 79 Query: 423 DDKSFKGV--TVGRGAQIVNGCINNPV-ALMCEQLGISMHKFGERCDLIQEGGRITDPTI 479 G+ T+G G+ I P L L K C G + Sbjct: 80 FVTRVPGLASTLGAGSPIDWNYTTIPQDGLDGRSLDYPRAKILGGCST--HNGMVYTRGS 137 Query: 480 DKRMDF----------HFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKE------ 523 + ++++L + + K D + I+ F + Sbjct: 138 KDDWNSWAGIIGDQGLGWDSILPAIKKAEKFTQDFTDQSVKGHIDPSVHGFDGKLSVSAA 197 Query: 524 -SGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVI 582 S I F++L + + + + N + W +H + + Sbjct: 198 YSNISFNDLLFETTKELNAEFPFKLDMNDGKPIGLGWTQYTI-----DNHAERSSSATSY 252 Query: 583 IEKLAEGLDIQLKSPVQCIDYSGDEVQ 609 +E + + + + + V + + Sbjct: 253 LESTGDNVHVLVNTLVTRVLSASGNGT 279 >2QAE-A nrPDB Length = 468 Score = 32.8 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 18/35 (51%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDR 416 K++++IG G GL G +VTV+E R Sbjct: 174 PKTMVVIGGGVIGLELGSVWARLGAEVTVVEFAPR 208 >3OC4-A nrPDB Length = 452 Score = 32.8 bits (73), Expect = 0.70, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 23/42 (54%) Query: 376 LPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 +P ++++V +IGAGP G+ A L V V E+ + + Sbjct: 141 VPLLENSQTVAVIGAGPIGMEAIDFLVKMKKTVHVFESLENL 182 >4CPD-A nrPDB Length = 347 Score = 32.4 bits (72), Expect = 0.72, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 33/90 (36%), Gaps = 9/90 (10%) Query: 366 VLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDK 425 +LS + + SV +IGAGP GL A G + A DRI R+ Sbjct: 153 ILSTAYGGLIQGQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKIL--AIDRIPERL---- 206 Query: 426 SFKGVTVGRGAQIVNGCINNPVALMCEQLG 455 GA +N NPV + + Sbjct: 207 ---ERAASLGAIPINAEQENPVRRVRSETN 233 >3HDH-A nrPDB Length = 302 Score = 32.4 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR 420 K V +IG G G A+ G V +++ + I + Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 53 >1F14-A nrPDB Length = 310 Score = 32.4 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR 420 K V +IG G G A+ G V +++ + I + Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 53 >2WOP-A nrPDB Length = 562 Score = 32.4 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 26/64 (40%), Gaps = 9/64 (14%) Query: 391 GPAGLAAARQLHNF-GIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVAL 449 GPAGL A L G E D GGR W + +G+ G I + + + V Sbjct: 75 GPAGLVPAPDLAEGPG------EVSD--GGRTWTYRLRRGLRYDDGTPITSDDVRHAVQR 126 Query: 450 MCEQ 453 + Q Sbjct: 127 VFAQ 130 >3SM8-A nrPDB Length = 381 Score = 32.1 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 383 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIG 418 ++IGAG AG + L G +V VLE + + G Sbjct: 10 ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPG 44 >2ZBW-A nrPDB Length = 335 Score = 32.1 bits (71), Expect = 0.94, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 423 V+I+GAGP GL A + G+ ++ GG++ Sbjct: 7 DVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTA 46 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 19/134 (14%), Positives = 41/134 (30%), Gaps = 9/134 (6%) Query: 594 LKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINS 653 L + ++ GD +VTT+ G Y+A+ V++ + + I ++ Sbjct: 84 LGERAETLEREGDLFKVTTSQGNAYTAKAVIIAAGVGAFEPRRIG----APGEREFEGRG 139 Query: 654 LGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKH--SVLMS 711 + + K Q V G D + PQ + + + Sbjct: 140 VYYAVKSKAEFQGKRVL---IVGGGDSAVDWALNLLDTARRITLIHRRPQFRAHEASVKE 196 Query: 712 VIAGEAVASVRTLD 725 ++ + L Sbjct: 197 LMKAHEEGRLEVLT 210 >2A9F-A nrPDB Length = 398 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Query: 344 RCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHN 403 R ++E ++ + G + ++ LL K S+++ G G AGL+ R+L Sbjct: 150 RLIKECHIPVFHDDQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLA 209 Query: 404 FG-IKVTVLE 412 G KVTV++ Sbjct: 210 AGATKVTVVD 219 >1QO8-A nrPDB Length = 566 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 V+++GAG AG A+ G V +++ GG Sbjct: 123 QVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSGG 158 >2BS2-A nrPDB Length = 660 Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 14/28 (50%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVTVL 411 ++IG G AGL AA G+ VL Sbjct: 7 DSLVIGGGLAGLRAAVATQQKGLSTIVL 34 >2CDU-A nrPDB Length = 452 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 33/78 (42%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR 434 L + K++ IIG+G G A N V +++ +R+ + +D + + Sbjct: 142 LFEEAPKAKTITIIGSGYIGAELAEAYSNQNYNVNLIDGHERVLYKYFDKEFTDILAKDY 201 Query: 435 GAQIVNGCINNPVALMCE 452 A VN + + VA E Sbjct: 202 EAHGVNLVLGSKVAAFEE 219 >5OC1-A nrPDB Length = 565 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 382 NKSVIIIGAGPAG-LAAARQLHNFGIKVTVLEAK 414 + +++GAG AG + AAR + + V VLEA Sbjct: 1 DFDYVVVGAGNAGNVVAARLTEDPDVSVLVLEAG 34 >4CUK-A nrPDB Length = 338 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 34/88 (38%), Gaps = 12/88 (13%) Query: 325 ALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKS 384 A +P+ H I + R RI R N + + L H K+ Sbjct: 99 AYSPEAVAEHAIGMMMTLNR------RIHRAYQRTRDANFSL------EGLTGFTMHGKT 146 Query: 385 VIIIGAGPAGLAAARQLHNFGIKVTVLE 412 +IG G G+AA R L FG+++ + Sbjct: 147 AGVIGTGKIGVAALRILKGFGMRLLAFD 174 >4FFM-A nrPDB Length = 363 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 21/44 (47%) Query: 382 NKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDK 425 K++ ++G G AA G+KV +++ + R + D+ Sbjct: 1 MKTICLVGGKLQGFEAAYLSKKAGMKVVLVDKNPQALIRNYADE 44 >3CUK-A nrPDB Length = 347 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 14/26 (53%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVT 409 V++IGAG GL+ A +H V Sbjct: 2 RVVVIGAGVIGLSTALCIHERYHSVL 27 >1VE9-A nrPDB Length = 347 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 14/26 (53%) Query: 384 SVIIIGAGPAGLAAARQLHNFGIKVT 409 V++IGAG GL+ A +H V Sbjct: 2 RVVVIGAGVIGLSTALCIHERYHSVL 27 >2QA1-A nrPDB Length = 500 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 380 YHNKSVIIIGAGPAGLAAARQLHNFG 405 + +VI++GAGPAG+ A +L G Sbjct: 9 RSDAAVIVVGAGPAGMMLAGELRLAG 34 >1XDI-A nrPDB Length = 499 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%) Query: 373 QYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRI 417 + L D +I++G+G G G+ VTV+ ++D + Sbjct: 173 RQLYDLDALPDHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHV 217 >5V36-A nrPDB Length = 453 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 34/245 (13%), Positives = 68/245 (27%), Gaps = 30/245 (12%) Query: 404 FGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMC-----EQLGISM 458 G KV + E K ++GG + V V INN A + + Sbjct: 29 HGAKVILFEGK-QVGGTCVNVGCVP-KKVMWYGAQVAETINNYAADYGFDVTTQAFHFDV 86 Query: 459 HKFGERCDL----------IQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVP 508 K + + G +D H ++V E L Sbjct: 87 LKQNRQAYIDRIHDSYERGFDSNGVERVYGYATFVDAHT---VEVAGEHYTAPHILIATG 143 Query: 509 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 568 + +I + + F EL+ + + Y + A + + F Sbjct: 144 GHALLPDIPGSEYGITSDGFFELDAIPKRTAVVGAGYIAVEISGILHALGSETHLFV--- 200 Query: 569 AGDHTLLTPGYSVIIEKLAEGLDI------QLKSPVQCIDYSGDEVQVTTTDGTGYSAQK 622 L I+ L + + P + I + + + + +G Y+ Sbjct: 201 -RRDRPLRKFDKEIVGTLVDEMKKDGPHLHTFSVPKEVIKNTDNSLTLILENGEEYTVDT 259 Query: 623 VLVTV 627 ++ + Sbjct: 260 LIWAI 264 >2HQM-A nrPDB Length = 479 Score = 30.9 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 22/62 (35%), Gaps = 11/62 (17%) Query: 355 FMTRKGLINTG---VLSVGADQYLLPKDY--------HNKSVIIIGAGPAGLAAARQLHN 403 + L+ TG + + L D K V+++GAG G+ A H Sbjct: 147 YSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHG 206 Query: 404 FG 405 G Sbjct: 207 LG 208 >5YPT-A nrPDB Length = 429 Score = 30.9 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 50/158 (31%), Gaps = 6/158 (3%) Query: 372 DQYLLPKDYHNKSVIIIGAGPAGL--AAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKG 429 D L D +K++ IG+ A + AAA + TVL + + Sbjct: 18 DSPDLGTDDDDKAMADIGS-MANIVNAAAYKHRRAAGPATVLAIGKATPPTAYSQSEYPD 76 Query: 430 VTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGR---ITDPTIDKRMDFH 486 + A +C+ GI+ F D+++ +P++D R D Sbjct: 77 FFFDITNTSHKTELKAKFARICKNSGINTRYFHCTEDILKANPSMCTYLEPSLDVRQDIA 136 Query: 487 FNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKES 524 + + + + P + ++ + Sbjct: 137 IREVPRLAEKAAIEALAEWGQPRDQITHVVFATTSGVN 174 >2JFH-A nrPDB Length = 445 Score = 30.9 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 20/41 (48%) Query: 379 DYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 419 DY K+V+IIG G GL+ G+ V++ + G Sbjct: 3 DYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPG 43 >1VDC-A nrPDB Length = 333 Score = 29.7 bits (65), Expect = 5.7, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 44/124 (35%), Gaps = 19/124 (15%) Query: 375 LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE---AKD-RIGGR---VWDDKSF 427 + + HN + I+G+GPA AA +K + E A D GG+ D ++F Sbjct: 1 MNGLETHNTRLCIVGSGPAAHTAAIYAARAELKPLLFEGWMANDIAPGGQLTTTTDVENF 60 Query: 428 KGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHF 487 G G + ++ +FG + ++ + ++ Sbjct: 61 PGFPEGILG-----------VELTDKFRKQSERFGTTIFT-ETVTKVDFSSKPFKLFTDS 108 Query: 488 NALL 491 A+L Sbjct: 109 KAIL 112 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.125 0.346 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,154,489 Number of Sequences: 36641 Number of extensions: 1259531 Number of successful extensions: 4133 Number of sequences better than 10.0: 265 Number of HSP's better than 10.0 without gapping: 340 Number of HSP's successfully gapped in prelim test: 88 Number of HSP's that attempted gapping in prelim test: 3485 Number of HSP's gapped (non-prelim): 616 length of query: 822 length of database: 10,336,785 effective HSP length: 105 effective length of query: 717 effective length of database: 6,489,480 effective search space: 4652957160 effective search space used: 4652957160 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (29.0 bits)