BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8N4T8 (237 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4CQM-B nrPDB 478 e-135 3RSH-A nrPDB 189 1e-48 1Q7C-A nrPDB 187 4e-48 4DMM-A nrPDB 187 5e-48 4JRO-A nrPDB 184 3e-47 2UVD-A nrPDB 183 5e-47 2PNF-A nrPDB 182 1e-46 3WOH-A nrPDB 181 2e-46 5CDY-A nrPDB 179 1e-45 2NM0-A nrPDB 177 2e-45 4BO1-A nrPDB 176 8e-45 4RZH-A nrPDB 175 1e-44 2CDH-G nrPDB 171 2e-43 4IIN-A nrPDB 169 1e-42 3OSU-A nrPDB 168 2e-42 4M8S-A nrPDB 167 3e-42 2C07-A nrPDB 167 5e-42 2HQ1-A nrPDB 167 5e-42 3FTP-A nrPDB 166 8e-42 2PH3-A nrPDB 164 4e-41 3LYL-A nrPDB 162 2e-40 3GRP-A nrPDB 158 2e-39 3F9I-A nrPDB 155 1e-38 3EMK-A nrPDB 155 1e-38 5OVL-A nrPDB 150 4e-37 5OVJ-A nrPDB 150 4e-37 4RZI-B nrPDB 145 1e-35 1UZM-A nrPDB 143 5e-35 4KMS-A nrPDB 138 2e-33 6NRP-A nrPDB 138 2e-33 3VZS-A nrPDB 134 5e-32 3EZL-A nrPDB 131 3e-31 4CQL-A nrPDB 129 9e-31 4K6F-A nrPDB 128 2e-30 4IIV-A nrPDB 124 3e-29 4AVY-A nrPDB 124 5e-29 5VT6-A nrPDB 122 2e-28 4NBT-A nrPDB 121 2e-28 6CI9-A nrPDB 118 3e-27 4MOW-A nrPDB 117 4e-27 2O23-A nrPDB 115 1e-26 2HSD-A nrPDB 114 5e-26 5B1Y-A nrPDB 112 9e-26 2GDZ-A nrPDB 111 3e-25 3OEC-A nrPDB 111 3e-25 5T5Q-A nrPDB 111 3e-25 3O4R-A nrPDB 110 4e-25 1YXM-A nrPDB 110 6e-25 2CFC-A nrPDB 110 6e-25 4DBZ-A nrPDB 109 1e-24 1K2W-A nrPDB 109 1e-24 5U9P-A nrPDB 108 2e-24 4E6P-A nrPDB 108 3e-24 4IS3-A nrPDB 107 4e-24 4NBV-A nrPDB 107 5e-24 1H5Q-A nrPDB 107 5e-24 1E3W-A nrPDB 107 5e-24 1GEG-A nrPDB 105 1e-23 1O5I-A nrPDB 103 5e-23 3V2G-A nrPDB 103 5e-23 5ITV-A nrPDB 103 6e-23 2B4Q-A nrPDB 102 1e-22 3AUT-A nrPDB 101 2e-22 3UN1-A nrPDB 100 5e-22 1DOH-A nrPDB 100 5e-22 3UF0-A nrPDB 100 7e-22 2ZAT-A nrPDB 99 1e-21 3U5T-A nrPDB 96 1e-20 5JS6-A nrPDB 96 2e-20 2EW8-A nrPDB 96 2e-20 3PPI-A nrPDB 96 2e-20 4HP8-A nrPDB 96 2e-20 1GEE-A nrPDB 96 2e-20 4Z9Y-A nrPDB 94 5e-20 3U4C-A nrPDB 94 5e-20 1NFF-A nrPDB 94 7e-20 4TRR-A nrPDB 92 2e-19 4FC7-A nrPDB 92 2e-19 1AE1-A nrPDB 92 2e-19 3OIC-A nrPDB 91 3e-19 5IZ4-A nrPDB 91 4e-19 3WYE-A nrPDB 91 4e-19 4CR6-A nrPDB 91 5e-19 3WTC-A nrPDB 89 2e-18 2FWM-X nrPDB 88 3e-18 2AG5-A nrPDB 88 3e-18 2AE2-A nrPDB 88 4e-18 5OJG-A nrPDB 87 5e-18 5JY1-A nrPDB 87 6e-18 1X1T-A nrPDB 85 2e-17 3RWB-A nrPDB 85 3e-17 3T7C-A nrPDB 84 4e-17 3OML-A nrPDB 84 5e-17 3R3S-A nrPDB 84 5e-17 3A28-C nrPDB 83 8e-17 3ZV3-A nrPDB 83 1e-16 3D3W-A nrPDB 82 2e-16 3UVE-A nrPDB 82 2e-16 2BGM-A nrPDB 81 5e-16 1HXH-A nrPDB 80 6e-16 3V8B-A nrPDB 80 8e-16 5ILO-A nrPDB 80 8e-16 3V2H-A nrPDB 80 9e-16 5YSS-A nrPDB 79 2e-15 2Q2Q-A nrPDB 78 3e-15 4DA9-A nrPDB 77 5e-15 2X9N-A nrPDB 77 6e-15 4EGF-A nrPDB 77 8e-15 5EJ2-A nrPDB 76 1e-14 1BDB-A nrPDB 75 2e-14 1AHH-A nrPDB 75 3e-14 5O3Z-A nrPDB 75 3e-14 4HBG-A nrPDB 75 4e-14 3RKU-A nrPDB 74 6e-14 3UCF-A nrPDB 74 7e-14 1W73-A nrPDB 73 1e-13 1CYD-A nrPDB 73 1e-13 4DRY-A nrPDB 72 2e-13 4GKB-A nrPDB 71 5e-13 3GDF-A nrPDB 70 1e-12 3W8F-A nrPDB 69 2e-12 4ZJU-A nrPDB 66 1e-11 1P33-A nrPDB 62 1e-10 3E9N-A nrPDB 62 2e-10 2BFA-A nrPDB 61 5e-10 4NR0-A nrPDB 60 6e-10 2QHX-A nrPDB 60 6e-10 2NWQ-A nrPDB 60 6e-10 4RGB-A nrPDB 60 7e-10 5KOI-A nrPDB 60 9e-10 2DKN-A nrPDB 58 3e-09 4M89-A nrPDB 57 1e-08 3GRK-A nrPDB 56 1e-08 3PXX-A nrPDB 56 1e-08 3K2E-A nrPDB 55 2e-08 5TF4-A nrPDB 55 2e-08 3OIG-A nrPDB 50 6e-07 1A27-A nrPDB 49 2e-06 6CGE-A nrPDB 49 2e-06 3U9L-A nrPDB 49 2e-06 5PGZ-A nrPDB 49 2e-06 1OAA-A nrPDB 49 3e-06 1FJH-A nrPDB 47 7e-06 1SNY-A nrPDB 47 8e-06 1MG5-A nrPDB 47 1e-05 1B15-A nrPDB 46 1e-05 2HRB-A nrPDB 46 2e-05 4ALL-A nrPDB 45 3e-05 3KZV-A nrPDB 45 4e-05 4Z3K-A nrPDB 44 5e-05 3DWF-A nrPDB 44 6e-05 4HWK-A nrPDB 44 6e-05 5I9N-A nrPDB 43 1e-04 2PD3-A nrPDB 43 1e-04 3BHI-A nrPDB 42 3e-04 1N5D-A nrPDB 39 0.002 5TQV-A nrPDB 39 0.002 5L51-A nrPDB 39 0.002 5WQO-A nrPDB 38 0.004 2PTG-A nrPDB 37 0.006 2NTV-A nrPDB 36 0.013 3O26-A nrPDB 35 0.023 4OYR-A nrPDB 34 0.051 4PSH-A nrPDB 33 0.12 4P71-A nrPDB 30 0.85 4V73-BP nrPDB 30 0.85 3F6S-A nrPDB 30 0.95 3SLK-A nrPDB 29 1.9 5LCX-A nrPDB 29 2.0 4B4O-A nrPDB 29 2.2 4ZRP-A nrPDB 28 2.7 3ORF-A nrPDB 28 2.9 5AOG-A nrPDB 28 4.2 1C0L-A nrPDB 27 5.2 5N2I-A nrPDB 27 6.3 2CF5-A nrPDB 27 8.5 >4CQM-B nrPDB Length = 244 Score = 478 bits (1229), Expect = e-135, Method: Compositional matrix adjust. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE Sbjct: 8 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 67 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR Sbjct: 68 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 127 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF Sbjct: 128 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 187 Query: 181 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL 237 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL Sbjct: 188 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL 244 >3RSH-A nrPDB Length = 251 Score = 189 bits (479), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 99/239 (41%), Positives = 149/239 (62%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G SRGIG+A+A+L+A +G ++ A + GA+A + LG + + +V Sbjct: 13 KVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPES 72 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 ++ + + G V+ LVN AGI RD LL+R K E+ + TNL KA +R M Sbjct: 73 IEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGM 132 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+NVGS+VG GN+GQ+ Y+A+K G++GF++++A+EVA + + VN VAPGF+ Sbjct: 133 MKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIE 192 Query: 183 TDMTKDLKEEHLKKN---IPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQLI 236 TDMTK L +E +P GR G+ E+A AV FL E+ YITG L V+GG+ +I Sbjct: 193 TDMTKALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGETLHVNGGMYMI 251 >1Q7C-A nrPDB Length = 244 Score = 187 bits (474), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 99/239 (41%), Positives = 149/239 (62%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K+ V G SRGIGRA+A+ +A +G ++ A + GA+A + LG + +V Sbjct: 6 KIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPAS 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 +++ E++ G V+ LVN AGI RD LL+R K E+ + TNL KA MR M Sbjct: 66 IESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAM 125 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+ +GS+VG GN GQ+ ++A+K GL+GFS++LA+EVA + I VNVVAPGF+ Sbjct: 126 MKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIE 185 Query: 183 TDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQLI 236 TDMT+ L ++ + +P GR G E+A+AV FL E+ YITG L V+GG+ ++ Sbjct: 186 TDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGGMYMV 244 >4DMM-A nrPDB Length = 269 Score = 187 bits (474), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 105/239 (43%), Positives = 146/239 (61%), Gaps = 7/239 (2%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS----CDV 57 D++ V G SRGIGRA+A +A G ++AV + GA + DV Sbjct: 28 DRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKADV 87 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++E +V+ F + + GR++ LVN AGI RD LL+R K +D S L NL G L +A Sbjct: 88 SQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCSRA 147 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A + M++Q+ G I+N+ S+VG GN GQ+ YSA+K G++G ++ +AKE+A + I VN VA Sbjct: 148 AAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNAVA 207 Query: 178 PGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YITGHVLVVDGGL 233 PGF+ TDMT +L E L + IPLGR+GE EVA V FL P YITG V+ +DGGL Sbjct: 208 PGFIATDMTSELAAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYITGQVINIDGGL 266 >4JRO-A nrPDB Length = 271 Score = 184 bits (466), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 109/243 (44%), Positives = 150/243 (61%), Gaps = 15/243 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD---LGGDH----LAFSC 55 KV V GGSRGIGR +A +A++G A I N G+ AA + L +H A Sbjct: 30 KVAVVTGGSRGIGRDIAINLAKEG---ANIFFNYNGSPEAAEETAKLVAEHGVEVEAMKA 86 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 +VA DV F++ + GRV+ LVN AGI RD LL+R K ++ ++ NL G+ L Sbjct: 87 NVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFLCT 146 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 KA RTM++Q+ G I+N+ S+VGL GN+GQ+ Y ASK G++G ++ A+E+A + I VN Sbjct: 147 KAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGINVNA 206 Query: 176 VAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVD 230 VAPGF+ TDMT L E E + IPLG +G T ++A+AV+FL S YITG L VD Sbjct: 207 VAPGFITTDMTDKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYITGQTLSVD 266 Query: 231 GGL 233 GG+ Sbjct: 267 GGM 269 >2UVD-A nrPDB Length = 246 Score = 183 bits (465), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 105/244 (43%), Positives = 150/244 (61%), Gaps = 17/244 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD-------LGGDHLAFSC 55 KV V G SRGIGRA+A +A++G + V N G + A + LG D +A Sbjct: 5 KVALVTGASRGIGRAIAIDLAKQGANVVV---NYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 DVA DV N ++ G+V+ LVN AG+ +D LL+R K E+ + ++TNL G L Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLCT 121 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 KA R M++Q+ G IVN+ S+VG+ GN GQ+ Y A+K G++G ++ AKE+A + I VN Sbjct: 122 KAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNA 181 Query: 176 VAPGFVHTDMTKDLKEEHLK----KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 229 +APGF+ TDMT D+ +E++K K IP +FGE ++A+AV F +S YITG L V Sbjct: 182 IAPGFIATDMT-DVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYITGQTLNV 240 Query: 230 DGGL 233 DGG+ Sbjct: 241 DGGM 244 >2PNF-A nrPDB Length = 248 Score = 182 bits (462), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 101/240 (42%), Positives = 143/240 (59%), Gaps = 9/240 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH----LAFSCDVA 58 KV V G +RGIGRA+A+ +A G + + + E AKA A ++ + ++ Sbjct: 8 KVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMNLL 67 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E + FEE+ + ++ LVN AGI RD L +R D L NL G+ L + + Sbjct: 68 SEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVTQNS 127 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 +R MI+Q+ G IVN+ S+VG GN GQ YS +K GL+GF+++LAKE+A + + VN VAP Sbjct: 128 LRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAP 187 Query: 179 GFVHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ TDMT L EE K+ IPLGRFG EVA+ V+FL + YITG V+ V+GG+ Sbjct: 188 GFIETDMTAVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITGEVIHVNGGM 247 >3WOH-A nrPDB Length = 251 Score = 181 bits (460), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 101/240 (42%), Positives = 151/240 (62%), Gaps = 7/240 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI-ARNLEGAKAAAGD---LGGDHLAFSCDVA 58 KV V GGSRG+GRA+A +AR G +A++ + AK G+ LGG ++ CDV+ Sbjct: 12 KVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRCDVS 71 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 V + + LG V+ LVN AGI RDGL K ED + ++TNL G+ L KA Sbjct: 72 DAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLFIKAC 131 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 I+++ GSI+N+ S+ G+ G++GQ+ Y+++K GL+G ++++AKE+A + +R N VAP Sbjct: 132 YFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNAVAP 191 Query: 179 GFVHTDMTKDLKEEHLKKN-IPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 G + TDMT+DL ++ + + +P+ RFG EVA V FL ES YITG V+ VDGG+ + Sbjct: 192 GLIATDMTQDLVDDSKRLDPVPMRRFGRPDEVAGLVAFLAGDESSYITGQVVCVDGGMAM 251 >5CDY-A nrPDB Length = 244 Score = 179 bits (453), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 96/239 (40%), Positives = 144/239 (60%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K+ V G SRGIGRA+A+L+ +G + A + +GA+A + LG + +V Sbjct: 6 KIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTS 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + + G V+ LVN AGI RD LL+R K ++ + TNL KA MR M Sbjct: 66 IDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVMRAM 125 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+ +GS+VG GN+GQ Y+A+K G++GFS++LA+EVA + I VNVVAPGF+ Sbjct: 126 MKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVAPGFIE 185 Query: 183 TDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQLI 236 TDMT+ L ++ + +P R G+ E+A AV FL E+ YI+G L V+GG+ +I Sbjct: 186 TDMTRTLTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGETLHVNGGMYMI 244 >2NM0-A nrPDB Length = 253 Score = 177 bits (450), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 99/238 (41%), Positives = 144/238 (60%), Gaps = 13/238 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 M + V GG+RGIG A+A+ A G ++A+ R+ E + LA CD+ Sbjct: 20 MSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEG--------FLAVKCDITDT 71 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V+ ++E+E+ G V L+ AG+ +D LL+R ED S + TNL G+ K A R Sbjct: 72 EQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANR 131 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 M++ + G +V + S+VGL G++GQ+ Y+ASK GLVGF+R+LA+E+ + I NVVAPGF Sbjct: 132 AMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGF 191 Query: 181 VHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 V TDMTK L +E ++ +PLGR+ E+A V FL ++ YITG V+ VDGGL Sbjct: 192 VDTDMTKVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGGL 249 >4BO1-A nrPDB Length = 269 Score = 176 bits (446), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 103/241 (42%), Positives = 145/241 (60%), Gaps = 8/241 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 KV V G SRGIG+A+A + R G + A + GA+ A L G + DV+ Sbjct: 28 KVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSS 87 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + V T E +++HLG+ +VN AGI RD LLVR K ++ ++TNL KA + Sbjct: 88 DESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSKAVL 147 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 R M + + G I+N+GS+VG GN+GQ+ Y+A+K GL GF+RALA+EV + I VN VAPG Sbjct: 148 RGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPG 207 Query: 180 FVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 F+ TDMT++L E E L IPLGR G+ E+A V FL + Y+TG + V+GG+ Sbjct: 208 FIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMY 267 Query: 235 L 235 + Sbjct: 268 M 268 >4RZH-A nrPDB Length = 247 Score = 175 bits (444), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 97/238 (40%), Positives = 143/238 (60%), Gaps = 7/238 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +V V G SRGIG+A A +A G ++ V A++ A A ++ GG+ +A +VA Sbjct: 7 QVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQANVA 66 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +V + R++ LVN AGI RD LL+R K ED + + NL G L KA Sbjct: 67 NADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAV 126 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M++Q+ G I+N+ S+ G+ GN GQ+ YSA+K G++GF++ +AKE+A + + VN VAP Sbjct: 127 SKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAP 186 Query: 179 GFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YITGHVLVVDGGL 233 GF+ TDMT++L E + + IPL R+G+ EVA + FL P YITG VDGG+ Sbjct: 187 GFIATDMTENLNAEPILQFIPLARYGQPEEVAGTIRFLATDPAAAYITGQTFNVDGGM 244 >2CDH-G nrPDB Length = 244 Score = 171 bits (433), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 99/242 (40%), Positives = 143/242 (59%), Gaps = 10/242 (4%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 V V G SRGIG+A+A + + G ++ V AR+ + A+ + + GG + F DV+K Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 E DV+ + G ++ +VN AGI RD LL+R K + NL G L +AA Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + M++++ G I+N+ S+VGL GN GQ+ Y+A+K G++GFS+ A+E A + I VNVV PG Sbjct: 123 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPG 182 Query: 180 FVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLLESP---YITGHVLVVDGGL 233 F+ +DMT L E+ KK IPLGR G+ VA V FL SP YITG +DGG+ Sbjct: 183 FIASDMTAKLGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQAFTIDGGI 242 Query: 234 QL 235 + Sbjct: 243 AI 244 >4IIN-A nrPDB Length = 271 Score = 169 bits (427), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 98/238 (41%), Positives = 138/238 (57%), Gaps = 9/238 (3%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDL---GGDHLAFSCDVAKEHD 62 + G S+GIG +A+ +A G ++ + R N E A A +L G D A E D Sbjct: 34 ITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESD 93 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + + + G +++LVN AG+ RD L ++ KTED + NL + + C+ A++ M Sbjct: 94 FIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVM 153 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 + + GS+VNV SI+G +GN GQ+ YSASKGG++ S++ A E A + IR N V PGF+ Sbjct: 154 SKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRFNSVTPGFIE 213 Query: 183 TDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 TDM +LK+E KNIPL R G EVA AV FLL S YITG L V+GGL + Sbjct: 214 TDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLKVNGGLYM 271 >3OSU-A nrPDB Length = 246 Score = 168 bits (426), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 97/245 (39%), Positives = 150/245 (61%), Gaps = 11/245 (4%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGDL---GGDHLAFSCD 56 M K V G SRGIGR++A +A +GY +AV A + E A+A ++ G D A + Sbjct: 3 MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQAN 62 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 VA +V+ +E+ G ++ LVN AGI RD LL+R K ++ + TNL G + Sbjct: 63 VADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQ 122 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A M++Q+ G+I+N+ S+VG GN GQ+ Y A+K G++G +++ A+E+A + I VN V Sbjct: 123 KATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAV 182 Query: 177 APGFVHTDMT----KDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVD 230 APGF+ +DMT +LKE+ L + IPL RFG+ ++A+ V FL ++ YITG + V+ Sbjct: 183 APGFIVSDMTDALSDELKEQMLTQ-IPLARFGQDTDIANTVAFLASDKAKYITGQTIHVN 241 Query: 231 GGLQL 235 GG+ + Sbjct: 242 GGMYM 246 >4M8S-A nrPDB Length = 248 Score = 167 bits (424), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 98/239 (41%), Positives = 145/239 (60%), Gaps = 10/239 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA---GDLGGDHLAFSCDVAK 59 K+ V G SRGIG A+A +A G ++ A + GA A + GG+ + A+ Sbjct: 9 KIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNS--AE 66 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 V+N ++EK G+++ LVN AGI RD LL+R K E+ + NL KA + Sbjct: 67 PETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKAVL 126 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 R M++Q+ G I+N+ S+VG+ GN+GQ+ Y+A+K GL+GFS+++A+EV + I VN VAPG Sbjct: 127 RGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCVAPG 186 Query: 180 FVHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 F+ TDMT+ L EE LGRFG+ ++A AV+FL ++ YITG L V+GG+ Sbjct: 187 FIDTDMTRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQTLHVNGGM 245 >2C07-A nrPDB Length = 285 Score = 167 bits (422), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 91/241 (37%), Positives = 140/241 (58%), Gaps = 8/241 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +KV V G RGIGR +A+++A+ + I+R + + ++ G + ++ DV+ Sbjct: 44 NKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVS 103 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 K+ ++ ++ V+ LVN AGI RD L +R K ++ L TNL + Sbjct: 104 KKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPI 163 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + MI + G I+N+ SIVGL GN GQ+ YS+SK G++GF+++LAKE+A + I VN +AP Sbjct: 164 SKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAP 223 Query: 179 GFVHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 GF+ +DMT + E+ ++ NIP GR G EVA+ FL +S YI G V V+DGGL Sbjct: 224 GFISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGL 283 Query: 234 Q 234 Sbjct: 284 S 284 >2HQ1-A nrPDB Length = 247 Score = 167 bits (422), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 98/241 (40%), Positives = 140/241 (58%), Gaps = 11/241 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV----IARNLEGAKAAAGDLGGDHLAFSCDVA 58 K V G SRG+G+A+A + G + + + +L+ G + + DV Sbjct: 6 KTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKGDVK 65 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 DV+N + GR++ LVN AGI RD L+++ +D L+TNL + L KA Sbjct: 66 NPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYLCTKAV 125 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M++Q+ G I+N+ SI G+ GN+GQ+ Y+ASK GL+GF++++AKE A K I N VAP Sbjct: 126 SKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYCNAVAP 185 Query: 179 GFVHTDMTKDL----KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 G + TDMT L KE +L NIPL RFG EVA+ V FL +S YITG V+ +DGG Sbjct: 186 GIIKTDMTDVLPDKVKEMYL-NNIPLKRFGTPEEVANVVGFLASDDSNYITGQVINIDGG 244 Query: 233 L 233 L Sbjct: 245 L 245 >3FTP-A nrPDB Length = 270 Score = 166 bits (420), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 105/243 (43%), Positives = 139/243 (57%), Gaps = 11/243 (4%) Query: 1 MDK-VCAVFGGSRGIGRAVAQLMARKGYRL---AVIARNLEGAKAAAGDLGGDHLAFSCD 56 +DK V V G SRGIGRA+A +AR+G + A EG AA G + + Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLN 85 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 V V E K G +N LVN AGI +D L +R K ++ + + TNL + Sbjct: 86 VNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRLSR 145 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A +R M++ +GG IVN+ S+VG GN GQ Y+A+K G+ G +RALA+E+ + I VN V Sbjct: 146 AVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNCV 205 Query: 177 APGFVHTDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLESP---YITGHVLVVD 230 APGF+ TDMTK L +E LK IPLGR G ++AHAV F L SP YITG L V+ Sbjct: 206 APGFIDTDMTKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAF-LASPQAGYITGTTLHVN 264 Query: 231 GGL 233 GG+ Sbjct: 265 GGM 267 >2PH3-A nrPDB Length = 245 Score = 164 bits (414), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 106/246 (43%), Positives = 141/246 (57%), Gaps = 28/246 (11%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAV-------------IARNLEGAKAAAGDLGGDHLAF 53 + G SRGIGRA+A +A G+ LA+ G+ A LG + L Sbjct: 6 ITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVA-VLGANLLEA 64 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 A H LG ++ LVN AGI RD LLVR K ED + L NL Sbjct: 65 EAATALVHQAAEV-------LGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFR 117 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 T + A++ M++ + G IVN+ S+VG+ GN GQ+ Y ASK GL+GF+RA+AKE A++ I V Sbjct: 118 TTREAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITV 177 Query: 174 NVVAPGFVHTDMT----KDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVL 227 N VAPGF+ T+MT +++KE +LK+ IP GRFG EVA AV FL+ ++ YITG L Sbjct: 178 NAVAPGFIETEMTERLPQEVKEAYLKQ-IPAGRFGRPEEVAEAVAFLVSEKAGYITGQTL 236 Query: 228 VVDGGL 233 VDGGL Sbjct: 237 CVDGGL 242 >3LYL-A nrPDB Length = 247 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 94/242 (38%), Positives = 140/242 (57%), Gaps = 8/242 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +KV V G SRGIG VA +A KG + A + A+ + G +++ Sbjct: 5 EKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNIS 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +QN F E++ ++ LVN AGI RD L++R ++ S ++TNL K Sbjct: 65 DIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSKEC 124 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 +R M++++ G I+++GS+VG GN GQ+ Y A+K G++GFS++LA EVA + I VNVVAP Sbjct: 125 VRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNVVAP 184 Query: 179 GFVHTDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 GF+ TDMT L +E + IP G+ GE ++A AV FL E+ YITG L V+GG+ Sbjct: 185 GFIATDMTDKLTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITGQTLHVNGGM 244 Query: 234 QL 235 + Sbjct: 245 YM 246 >3GRP-A nrPDB Length = 266 Score = 158 bits (399), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 88/235 (37%), Positives = 137/235 (58%), Gaps = 5/235 (2%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V G + GIG A+A+ +G + + + K A DLG D FS +++ ++ Sbjct: 32 VTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDRKSIKQL 91 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 E E+ + ++ LVN AGI RDGL VR + +D L NL + + + +M++++ Sbjct: 92 AEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSMMRRR 151 Query: 127 GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 G I+N+ SIVG+ GN GQ+ Y A+K GL+GFS+ALA+E+A + I VN +APGF+ + MT Sbjct: 152 YGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIAPGFIKSAMT 211 Query: 187 KDLKE---EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQLI 236 L E E + IP+ R G E+A A V+L E+ Y+TG L ++GG+ +I Sbjct: 212 DKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTGQTLHINGGMAMI 266 >3F9I-A nrPDB Length = 249 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 89/239 (37%), Positives = 138/239 (57%), Gaps = 9/239 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G S GIG A+A+L+ + G ++ + N E K+ L ++ C++A + + Sbjct: 15 KTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLANKEE 74 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 N L ++ LV AGI D L +R K +D + NL + + + A++ M Sbjct: 75 CSN----LISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKM 130 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 IQ++ G I+N+ SIVG+ GN GQ+ Y ASK GL+G +++L+ EVA + I VN VAPGF+ Sbjct: 131 IQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGFIK 190 Query: 183 TDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 +DMT L E E + + IPLG +G +VA+AV FL + YITG L V+GG+ ++ Sbjct: 191 SDMTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTLHVNGGMLMV 249 >3EMK-A nrPDB Length = 246 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 88/235 (37%), Positives = 137/235 (58%), Gaps = 5/235 (2%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V G + G+G A+A+ + +G + + E K A +LG F +++ V+ Sbjct: 12 VTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDREAVKAL 71 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 ++ E+ +G V+ LVN AGI RDGL VR ED + L NL + M++++ Sbjct: 72 GQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTRELTHPMMRRR 131 Query: 127 GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 G I+N+ SIVG+ GN GQ+ Y ASK GL+GFS++LA+E+A + + VN +APGF+ + MT Sbjct: 132 NGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAPGFIESAMT 191 Query: 187 KDLKEEH---LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQLI 236 L E+ + NIP+ R G ++A AVV+L E+ Y+TG L V+GG+ +I Sbjct: 192 GKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTLHVNGGMAMI 246 >5OVL-A nrPDB Length = 300 Score = 150 bits (380), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 91/235 (38%), Positives = 139/235 (59%), Gaps = 15/235 (6%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V GG+RGIG A+A+ +A G+++AV R A DL G CDV V Sbjct: 73 VTGGNRGIGLAIARRLAADGHKVAVTHRG----SGAPDDLFG----VQCDVTDSAAVDRA 124 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 F+E+E+H G V LV AGI++D L+R E ++TNL G+ + A RTM +++ Sbjct: 125 FKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKR 184 Query: 127 GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 G I+ +GS+ G+ G Q+ Y+A+K GL+G +R++++E+A+ + NVVAPG++ T+MT Sbjct: 185 FGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMT 244 Query: 187 KDLKEEHLKKN----IPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 + L +E ++ IP R G EVA AV FL ++ YI G V+ VDGG+ + Sbjct: 245 RAL-DERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGMGM 298 >5OVJ-A nrPDB Length = 256 Score = 150 bits (380), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 91/235 (38%), Positives = 139/235 (59%), Gaps = 15/235 (6%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V GG+RGIG A+A+ +A G+++AV R A DL G CDV V Sbjct: 29 VTGGNRGIGLAIARRLAADGHKVAVTHRG----SGAPDDLFG----VQCDVTDSAAVDRA 80 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 F+E+E+H G V LV AGI++D L+R E ++TNL G+ + A RTM +++ Sbjct: 81 FKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKR 140 Query: 127 GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 G I+ +GS+ G+ G Q+ Y+A+K GL+G +R++++E+A+ + NVVAPG++ T+MT Sbjct: 141 FGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMT 200 Query: 187 KDLKEEHLKKN----IPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 + L +E ++ IP R G EVA AV FL ++ YI G V+ VDGG+ + Sbjct: 201 RAL-DERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGMGM 254 >4RZI-B nrPDB Length = 240 Score = 145 bits (367), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 89/236 (37%), Positives = 128/236 (54%), Gaps = 13/236 (5%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 DKV V GG+RGIG A+ +L+ G ++A +G A L +V Sbjct: 8 DKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA-------LGVVANVTDLE 60 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + E+ LG V +V AGI +D + D + L+ NL G + K + Sbjct: 61 SMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEG 120 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M +++ GSIV + SI G +GN GQ+ YSA+K G++G ++LA+E AR +R N VAPGF+ Sbjct: 121 MYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFI 180 Query: 182 HTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE---SPYITGHVLVVDG 231 T+MT ++E E + K IP RFG+ E+A AV FLL S Y+TG VL V+G Sbjct: 181 DTEMTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVNG 236 >1UZM-A nrPDB Length = 247 Score = 143 bits (361), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 87/234 (37%), Positives = 134/234 (57%), Gaps = 13/234 (5%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V GG+RGIG A+AQ +A G+++AV R G+ A G G DV V Sbjct: 20 VTGGNRGIGLAIAQRLAADGHKVAVTHR---GSGAPKGLFG-----VEVDVTDSDAVDRA 71 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 F +E+H G V LV+ AG++ D L+R E ++ NL G+ + A R+M + + Sbjct: 72 FTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK 131 Query: 127 GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 G ++ +GS+ GL G Q+ Y+ASK G++G +R++A+E+++ + NVVAPG++ TDMT Sbjct: 132 FGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMT 191 Query: 187 KDLKEEHLK---KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 + L E + + IP R G EVA V FL ++ YI+G V+ VDGG+ + Sbjct: 192 RALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGM 245 >4KMS-A nrPDB Length = 249 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 89/246 (36%), Positives = 135/246 (54%), Gaps = 15/246 (6%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR---NLEGAKAAAGDLGGDHLAFSC-D 56 M ++ V GG+RGIG+A A + KG L V+A N + AK G + C + Sbjct: 9 MSEIAIVTGGTRGIGKATALELKNKG--LTVVANFFSNYDAAKEMEEKYG---IKTKCWN 63 Query: 57 VAKEHDVQNTFEELEKHLGR-VNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 VA + + +E+E+ + V+ LVN AGI +D +L R +D ++ NL Sbjct: 64 VADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMS 123 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + M M Q G IVN+ SI G GQ+ YSA+K G++GF++ALA+E A K I VN Sbjct: 124 SSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNC 183 Query: 176 VAPGFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLLESP--YITGHVLVVD 230 +APG++ T+M + E+ L K +IP R G+ E+A AV FL++ +ITG + ++ Sbjct: 184 IAPGYIATEMVGAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISIN 243 Query: 231 GGLQLI 236 GG +I Sbjct: 244 GGHNMI 249 >6NRP-A nrPDB Length = 263 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 93/241 (38%), Positives = 136/241 (56%), Gaps = 9/241 (3%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG-AKAAAGD---LGGDHLAFSCD 56 M + V G SRGIG+A+A +A+ G+ + V AR+ + A+ + LG + D Sbjct: 23 MTRRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFD 82 Query: 57 VAKEHDVQNTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 V + VQ E+ +E+H G ++NA G+ DG +D + T+L G Sbjct: 83 VNERQTVQQILEQDVEQHGGFYGVVLNA-GLTHDGAFPALTDQDWDEVISTSLDGFYNVL 141 Query: 116 KAAMRTMIQ-QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 K + MI ++GG IV + S+ G+ GN GQ YSA+K GL+G ++ALA E+A++KI VN Sbjct: 142 KPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVN 201 Query: 175 VVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 VAPG + T+M D +EH K IPL R G+ EVA V FL E+ Y+T V+ V+GG Sbjct: 202 CVAPGLIETEMVTDEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVISVNGG 261 Query: 233 L 233 L Sbjct: 262 L 262 >3VZS-A nrPDB Length = 257 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 88/248 (35%), Positives = 133/248 (53%), Gaps = 21/248 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA----------RNLEGAKAAAGDLGGDHLA 52 ++ V GG GIG A+ Q +A+ G+R V+A + LE KA LG D +A Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFR--VVAGCGPNSPRREKWLEQQKA----LGFDFIA 68 Query: 53 FSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112 +VA + F++++ +G V+ L+N AGI RD + + D + + TNL Sbjct: 69 SEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLF 128 Query: 113 LTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 172 K + M + G IVN+ S+ G KG GQ+ YS +K GL GF+ ALA+EVA K + Sbjct: 129 NVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVT 188 Query: 173 VNVVAPGFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLL--ESPYITGHVL 227 VN V+PG++ TDM K ++++ L K IP+ R G E+A +L ES + TG Sbjct: 189 VNTVSPGYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADF 248 Query: 228 VVDGGLQL 235 ++GGL + Sbjct: 249 SLNGGLHM 256 >3EZL-A nrPDB Length = 256 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 81/246 (32%), Positives = 131/246 (53%), Gaps = 17/246 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV--------IARNLEGAKAAAGDLGGDHLAFS 54 ++ V GG GIG ++ Q + + G+R+ + LE KA LG D A Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKA----LGFDFYASE 69 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 +V + F++++ +G ++ LVN AGI RD + + ED + + TNL Sbjct: 70 GNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNV 129 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 K + M+++ G I+N+ S+ G KG GQ+ YS +K G+ GF+ +LA+EVA K + VN Sbjct: 130 TKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVN 189 Query: 175 VVAPGFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 229 V+PG++ TDM K ++ + L+K IP+ R G E+ V +L ES + TG + Sbjct: 190 TVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSL 249 Query: 230 DGGLQL 235 +GGL + Sbjct: 250 NGGLHM 255 >4CQL-A nrPDB Length = 261 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 85/244 (34%), Positives = 131/244 (53%), Gaps = 17/244 (6%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVI----------ARNLEGAKAAAGDLGGDHLAFSCD 56 V G GIGRAV+ +A +G +A R L G + G G+H AF D Sbjct: 16 VTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQAD 75 Query: 57 VAKEHDVQNTFEELEKHLGRV-NFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 V++ + E+++ R + +V+ AGI +D L+ +D + NL G+ L Sbjct: 76 VSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVT 135 Query: 116 KAAMRTMIQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 +AA + ++ GSI+N+ SIVG GN GQ+ Y+ASK G++G ++ A+E+ R IR N Sbjct: 136 QAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCN 195 Query: 175 VVAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 229 V PGF+ T MT+ + + + + + IP+G G+ +VA V FL +S YITG + V Sbjct: 196 SVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEV 255 Query: 230 DGGL 233 GGL Sbjct: 256 TGGL 259 >4K6F-A nrPDB Length = 255 Score = 128 bits (321), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 81/243 (33%), Positives = 133/243 (54%), Gaps = 10/243 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI-ARNLEGAKAAAGDL---GGDHLAFSCDVA 58 ++ V GG G+G AV+ + G+R+ V + N GA ++ G + A+ DVA Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVA 71 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 Q E++ + +G V+ LVN AGI RD L + + + + TNL K Sbjct: 72 DHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPV 131 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 M+++ G IVN+ S+ G KG+ GQ+ Y+A+K G+ GF+++LA E+ARK + VN V+P Sbjct: 132 CDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNTVSP 191 Query: 179 GFVHTDM----TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 G++ T M +D+ + + IP GR G+ EVA V +L E+ ++TG + ++GG Sbjct: 192 GYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAINGG 251 Query: 233 LQL 235 + Sbjct: 252 QHM 254 >4IIV-A nrPDB Length = 267 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 85/244 (34%), Positives = 135/244 (55%), Gaps = 13/244 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGDL---GGDHLAFSCD 56 M + V G S+GIGRA+A+ +A G+ + V R+ GA+ + GG+ S D Sbjct: 25 MSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFD 84 Query: 57 VAKEHDVQNTFE-ELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 VA + E E+ +H G +V+ AGI RD +D + +HTNL Sbjct: 85 VANREQCREVLEHEIAQH-GAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVI 143 Query: 116 KAAMRTMI-QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 + + MI +QGG I+ + S+ G+ GN GQ YSA+K G++G ++ALA E+A++KI VN Sbjct: 144 QPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVN 203 Query: 175 VVAPGFVHTDMTKDLKEEHLKKN---IPLGRFGETIEVAHAVVFLLE--SPYITGHVLVV 229 +APG + T M +++E LK+ IP+ R G+ EVA +L+ + Y+T V+ + Sbjct: 204 CIAPGLIDTGMI-EMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQVISI 262 Query: 230 DGGL 233 +GG+ Sbjct: 263 NGGM 266 >4AVY-A nrPDB Length = 242 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 86/236 (36%), Positives = 124/236 (52%), Gaps = 23/236 (9%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF---SCDVAKEHDV 63 V GGS GIG A+A A G + + + +G A H D+ + Sbjct: 16 VTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAP------RHPRIRREELDITDSQRL 69 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 Q FE L R++ LVN AGI+RD T + V L NL +ML + A R ++ Sbjct: 70 QRLFEALP----RLDVLVNNAGISRDREEYDLATFERV--LRLNLSAAMLASQLA-RPLL 122 Query: 124 QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 Q+GGSI+N+ S+ G++ + YSASKG +V +R+LA E A ++IRVN +APG++ T Sbjct: 123 AQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDT 182 Query: 184 DMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 + LK + + + PL R+GE EVA A FL + ++TG VL VDGG Sbjct: 183 PLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGG 238 >5VT6-A nrPDB Length = 269 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 78/243 (32%), Positives = 132/243 (54%), Gaps = 10/243 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI--ARN--LEGAKAAAGDLGGDHLAFSCDVA 58 +V V GG G+G A+++ + G +AV RN + D G D A++ DVA Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVA 85 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + E++ G+V+ L+N AGI RD ++ D + + T+L K Sbjct: 86 DFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQF 145 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M++++ G IVN+GS+ G +G GQ+ Y+++K G+ GF++ LA E A++ I VN V+P Sbjct: 146 IAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTVSP 205 Query: 179 GFVHTDM----TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 G++ T M +D+ E + IP+GR G EVA + FL ++ ++TG L ++GG Sbjct: 206 GYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLAINGG 265 Query: 233 LQL 235 + + Sbjct: 266 MHM 268 >4NBT-A nrPDB Length = 240 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 129/248 (52%), Gaps = 29/248 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS-------- 54 KV + GG++G+G+A+A A EGAK AGDLG L +S Sbjct: 7 KVAVITGGAKGLGQAIALAYAE------------EGAKVIAGDLG--DLTYSHPNVEGMY 52 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 +V V+ ++ + G+++ LVN AGI +D + + + + NL G Sbjct: 53 LNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNL 112 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK--KIR 172 + M GSI+N+ S+VG+ GN GQ+ Y+A+K G++G + AKE A K +R Sbjct: 113 TRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVR 172 Query: 173 VNVVAPGFVHTDMTKDLKEEHLKKNIP---LGRFGETIEVAHAVVFLL--ESPYITGHVL 227 VN +APG++ TD+ K + ++ L K L R G+ E+A +FL ++ Y+TG + Sbjct: 173 VNAIAPGYIMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTI 232 Query: 228 VVDGGLQL 235 V+GG++L Sbjct: 233 NVNGGMRL 240 >6CI9-A nrPDB Length = 259 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 78/235 (33%), Positives = 115/235 (48%), Gaps = 9/235 (3%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH---LAFSCDVAKEHDV 63 V GGS+GIGR +A+ A G + + RN + DL G A DV D Sbjct: 14 VTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDA 73 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 + T E G ++ + AGI G L +D+ L N G++ +AA++ + Sbjct: 74 RRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALT 133 Query: 124 QQQGGSIVNVGSIVG-LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 G +V SI G + G G S Y ASK +GF R A E+A KKI +N V PG + Sbjct: 134 ASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIM 193 Query: 183 TDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 T+ ++ +++L + IP GR G ++ +A +F E+ Y+TG LVVDGG Sbjct: 194 TEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGG 248 >4MOW-A nrPDB Length = 256 Score = 117 bits (293), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 85/245 (34%), Positives = 130/245 (53%), Gaps = 16/245 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKA---AAGDLGGDHLAFSCDVA 58 KV V G S+GIG A+A+ +A +G + V A + GA A A + GG +A DV+ Sbjct: 15 KVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGGDVS 74 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 K D Q + + GR++ LVN +G+ + E Q TN+ G +LT +AA Sbjct: 75 KAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLTTQAA 134 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 ++ + +G SI+N+ S+V +VYS +KG + + LA E+ +KIRVN + P Sbjct: 135 VKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVNAINP 192 Query: 179 GFVHTDMT-------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 229 G + T+ T DL+ + L + PLGR GE ++A VFL ++ ++TG LVV Sbjct: 193 GMIVTEGTHSAGIIGSDLEAQVLGQT-PLGRLGEPNDIASVAVFLASDDARWMTGEHLVV 251 Query: 230 DGGLQ 234 GGL Sbjct: 252 SGGLN 256 >2O23-A nrPDB Length = 265 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 124/248 (50%), Gaps = 16/248 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V + GG+ G+G A A+ + +G ++ G +A A LG + + DV E DV Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 73 Query: 64 QNTFEELEKHLGRVNFLVNAAGI---NRDGLLVRTKT---EDMVSQLHTNLLGSMLTCKA 117 Q + GRV+ VN AGI ++ L + +T ED L NL+G+ + Sbjct: 74 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 133 Query: 118 AMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A I Sbjct: 134 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 193 Query: 172 RVNVVAPGFVHTDMTKDLKEE---HLKKNIPL-GRFGETIEVAHAVVFLLESPYITGHVL 227 RV +APG T + L E+ L +P R G+ E AH V ++E+P++ G V+ Sbjct: 194 RVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVI 253 Query: 228 VVDGGLQL 235 +DG +++ Sbjct: 254 RLDGAIRM 261 >2HSD-A nrPDB Length = 253 Score = 114 bits (284), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 89/237 (37%), Positives = 115/237 (48%), Gaps = 7/237 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS-CDVAKEH 61 K + GG+RG+G A+ G R+ V+A L+ AA GD + DV E Sbjct: 6 KTVIITGGARGLGAEAARQAVAAGARV-VLADVLDEEGAATARELGDAARYQHLDVTIEE 64 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 D Q + G V+ LVN AGI+ L E + NL G + K + Sbjct: 65 DWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPA 124 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M GGSIVN+ S GL G + S Y ASK G+ G S+ A E+ +IRVN V PG Sbjct: 125 MKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMT 184 Query: 182 HTDMTKDL---KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 +T MT + + E N P+GR GE E+A AVV LL S Y+TG L VDGG Sbjct: 185 YTPMTAETGIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGAELAVDGGW 241 >5B1Y-A nrPDB Length = 270 Score = 112 bits (281), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 86/240 (35%), Positives = 120/240 (50%), Gaps = 14/240 (5%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARN----LEGAKAAAGDLGG-DHLAFSCDVAKEH 61 V GGSRGIGRA AR+G+ + + ++ E A LG + DV Sbjct: 28 VTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGDPD 87 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 V + + + +N LVNAAG+ + G + T + L NL G L K + Sbjct: 88 SVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTKLLLPL 147 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSV-YSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 + + + SIVNV SI G GN V YSASK G++G ++ LA ++A IRVN VAP F Sbjct: 148 LRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAPSF 207 Query: 181 VHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLLE---SPYITGHVLVVDGG 232 V TDMT+ K E + PL + +VA A++FL + S ITGHVL ++ G Sbjct: 208 VETDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITGHVLSINAG 267 >2GDZ-A nrPDB Length = 267 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 78/248 (31%), Positives = 130/248 (52%), Gaps = 29/248 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG---AKAAAGDLGGDH--LAFSCDV 57 KV V G ++GIGRA A+ + KG ++A++ NLE KAA + L CDV Sbjct: 8 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCDV 67 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 A + +++TF ++ H GR++ LVN AG+N + +T ++VS + LG Sbjct: 68 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG------- 120 Query: 118 AMRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSR--ALAKEVARKKIR 172 + M +Q GG I+N+ S+ GL + Q VY ASK G+VGF+R ALA + +R Sbjct: 121 -LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 179 Query: 173 VNVVAPGFVHTDMTKDLKEE-----------HLKKNIPLGRFGETIEVAHAVVFLLESPY 221 +N + PGFV+T + + +++E H+K I + +A+ ++ L+E Sbjct: 180 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 239 Query: 222 ITGHVLVV 229 + G ++ + Sbjct: 240 LNGAIMKI 247 >3OEC-A nrPDB Length = 317 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 89/268 (33%), Positives = 131/268 (48%), Gaps = 40/268 (14%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI-----ARNLEGAKAAAGDL----------G 47 KV + G +RG GR A +A+ G + I NL+ A+ + +L G Sbjct: 47 KVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVEEQG 106 Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN 107 +A DV +Q +E G ++ LV+ GI+ G +V + L TN Sbjct: 107 RRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDILQTN 166 Query: 108 LLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 L+G+ C+A + +MI++ QGGS++ V S VGL+G GQS Y+ASK G+ G +LA EV Sbjct: 167 LIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSLANEV 226 Query: 167 ARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIP--------------------LGRFGET 206 R IRVN V PG V+T+M L E+ LK +P + E Sbjct: 227 GRHNIRVNSVNPGAVNTEMA--LNEKLLKMFLPHLENPTREDAAELFSQLTLLPIPWVEP 284 Query: 207 IEVAHAVVFLL--ESPYITGHVLVVDGG 232 +V++AV +L E+ YI G + VDGG Sbjct: 285 EDVSNAVAWLASDEARYIHGAAIPVDGG 312 >5T5Q-A nrPDB Length = 247 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 74/242 (30%), Positives = 120/242 (49%), Gaps = 12/242 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH--LAFSCDVAK 59 ++ + G + GIGRA+A+L G L + + EG A A LG D + Sbjct: 9 NRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASS 68 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 D + T + G ++FLV +AGI + D + NL G CK A+ Sbjct: 69 ADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCKRAL 128 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + ++ SIV + S+ +G + Y A+KG +V +RAL++E+A K RVN V+PG Sbjct: 129 PAL--KEDSSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELA-PKTRVNGVSPG 185 Query: 180 FVHTDMTKDLKEEHLKKNI---PLGRFGETIEVAHAVVFLLESP---YITGHVLVVDGGL 233 + T MT +L + + + + PL R G+ E+A + FL SP ++TG + V+GG+ Sbjct: 186 IIETPMTSELLKTRMDETMTQTPLKRLGKPSEIASVIAFLC-SPAASFVTGETIQVNGGI 244 Query: 234 QL 235 + Sbjct: 245 YM 246 >3O4R-A nrPDB Length = 261 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 11/242 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS---CDVA 58 +KV V + GIG A+A+ +A+ G + V +R + A L G+ L+ + C V Sbjct: 15 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 74 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ-LHTNLLGSMLTCKA 117 K D + K G ++ LV+ A +N + TE++ + L N+ L KA Sbjct: 75 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 134 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + M ++ GGS+V V SI + G S Y+ SK L+G ++ LA E+A + IRVN +A Sbjct: 135 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 194 Query: 178 PGFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVD 230 PG + T ++ L KEE +K+ + + R GE + A V FL ++ YITG +VV Sbjct: 195 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVG 254 Query: 231 GG 232 GG Sbjct: 255 GG 256 >1YXM-A nrPDB Length = 303 Score = 110 bits (274), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 81/253 (32%), Positives = 126/253 (49%), Gaps = 24/253 (9%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH--------LAFS 54 +V V GG+ GIG+A+ + + G + + +R LE K+AA +L + + Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 C++ E +V N + G++NFLVN G ++ + L TNL G+ Sbjct: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYS-ASKGGLVGFSRALAKEVARKKIRV 173 CKA + +++ GGSIVN+ IV K +V+S A++ G+ +++LA E A IR+ Sbjct: 139 CKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRI 196 Query: 174 NVVAPGFVHTDMT--------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YI 222 N VAPG +++ + E +K IP R G EV+ V FLL SP +I Sbjct: 197 NCVAPGVIYSQTAVENYGSWGQSFFEGSFQK-IPAKRIGVPEEVSSVVCFLL-SPAASFI 254 Query: 223 TGHVLVVDGGLQL 235 TG + VDGG L Sbjct: 255 TGQSVDVDGGRSL 267 >2CFC-A nrPDB Length = 250 Score = 110 bits (274), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 82/251 (32%), Positives = 121/251 (48%), Gaps = 16/251 (6%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVI---ARNLEGAKAAAGDLGGDH-LAFSCD 56 M +V V G S G G A+A +G R+A + A LE D L D Sbjct: 1 MSRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRAD 60 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGI---NRDGLLVRTKTEDMVSQLHTNLLGSML 113 VA E DV + G ++ LVN AGI + G+L T E + N+ G L Sbjct: 61 VADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFL 120 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 C+A + M+ Q G IVN+ S+ L G+S Y+ SKG ++ ++++A + A IR Sbjct: 121 GCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRC 180 Query: 174 NVVAPGFVHTDMTK------DLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGH 225 N V PG + T MT+ +L+++ L + IP G +VA AV+FL ++ Y+ G Sbjct: 181 NAVCPGMIETPMTQWRLDQPELRDQVLAR-IPQKEIGTAAQVADAVMFLAGEDATYVNGA 239 Query: 226 VLVVDGGLQLI 236 LV+DG I Sbjct: 240 ALVMDGAYTAI 250 >4DBZ-A nrPDB Length = 281 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 21/253 (8%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +V V G + GIG +A+ + ++G R+ V AR EG + +L G + +CDV Sbjct: 26 SEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVR 85 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +++ + + G V+ LVN AG G E + + TNL G K Sbjct: 86 SVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQV 145 Query: 119 MRT--MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 ++ M+++ G IVN+ S G +G + YSASK G+VGF++AL E+AR I VN V Sbjct: 146 LKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAV 205 Query: 177 APGFVHTDMTKDLKEEH--------------LKKNIPLGRFGETIEVAHAVVFLL--ESP 220 PGFV T M ++E + + +P+GR+ + EVA V +L+ + Sbjct: 206 CPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPGAA 265 Query: 221 YITGHVLVVDGGL 233 +T L V GGL Sbjct: 266 AVTAQALNVCGGL 278 >1K2W-A nrPDB Length = 256 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 115/247 (46%), Gaps = 17/247 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G +RGIGRA A+ R+G R+A+ NLE A+A A ++G A + DV + Sbjct: 6 KTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVTDQAS 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + EL G ++ LVN A + +V E N+ G++ +A R M Sbjct: 66 IDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQAVARAM 125 Query: 123 IQ-QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 I +GG I+N+ S G +G + VY A+K ++ +++ + R I VN +APG V Sbjct: 126 IAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAIAPGVV 185 Query: 182 --------------HTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGH 225 + ++ + K+ + +P GR G ++ +FL E+ YI Sbjct: 186 DGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEADYIVAQ 245 Query: 226 VLVVDGG 232 VDGG Sbjct: 246 TYNVDGG 252 >5U9P-A nrPDB Length = 265 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 74/239 (30%), Positives = 117/239 (48%), Gaps = 14/239 (5%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL-----GGDHLAFSCDVAKEH 61 + G RGIG +A+ +A G + + RN E A A DH F DVA+ Sbjct: 25 ITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF--DVAEHA 82 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 V+ +E E +G ++ LVN AGI R L + +D + + NL G +A R Sbjct: 83 QVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVAQAVARH 142 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 MI + G I+N+ S+ + Y+A+KG + ++ + + AR I+ N +APG+ Sbjct: 143 MIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQANGLAPGYF 202 Query: 182 HTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 T++ + L + + L K P GR+G+ E+ A +FL S ++ G L VDGGL Sbjct: 203 ETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFVNGQTLFVDGGL 261 >4E6P-A nrPDB Length = 259 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 120/247 (48%), Gaps = 17/247 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G +RGIGRA A+ R+G +A+ ++E A+ AA ++G A DV ++ Sbjct: 9 KSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDVTRQDS 68 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + +H G ++ LVN A + +V E N+ G++ T +AA R M Sbjct: 69 IDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQAAARQM 128 Query: 123 IQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 I Q +GG I+N+ S G +G + ++Y A+K ++ +++ ++ + +I VN +APG V Sbjct: 129 IAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAIAPGVV 188 Query: 182 ---HTDMTKDL-----------KEEHLKKNIPLGRFGETIEVAHAVVFL--LESPYITGH 225 H D L K+ + + +P GR G ++ +FL ES YI Sbjct: 189 DGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAESDYIVSQ 248 Query: 226 VLVVDGG 232 VDGG Sbjct: 249 TYNVDGG 255 >4IS3-A nrPDB Length = 268 Score = 107 bits (267), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 119/244 (48%), Gaps = 12/244 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH-----LAFSCD 56 DKV + GG+RGIG A A++ G ++++ E A L + L F+ D Sbjct: 25 DKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPD 84 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 + V ++ + GR++ ++N AGI + + R E+ + N+ G Sbjct: 85 LTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVFNGAW 144 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A + M + G I+N S+ G+ G+ Y ASK ++G + L +E+ RK IRV V Sbjct: 145 CAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIRVVGV 204 Query: 177 APGFVHTDMT----KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVD 230 APG V+TDMT ++ E +LK +P+ R E E+A+ +FL + IT + VD Sbjct: 205 APGVVNTDMTNGNPPEIMEGYLKA-LPMKRMLEPEEIANVYLFLASDLASGITATTVSVD 263 Query: 231 GGLQ 234 G + Sbjct: 264 GAYR 267 >4NBV-A nrPDB Length = 246 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 76/244 (31%), Positives = 123/244 (50%), Gaps = 14/244 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL-----AFSCDV 57 +V + G + GIG A AQ A G V+ +++ A+ A+ DV Sbjct: 6 RVAIITGAAAGIGFATAQRFAEDG--AIVVLCDVQEARVREAAARLAATGATVSAYRVDV 63 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + +V + RV+ LVN AGI +D L + + + NL G + C Sbjct: 64 TRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKG-VFNCAQ 122 Query: 118 AMRTMIQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A+ ++ +QG G I+N S+VGL GN GQ+ Y+ASK G++GF++ A+E+ K +RVN V Sbjct: 123 AVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVNAV 182 Query: 177 APGFVHTDMTKDLKEEHLK---KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDG 231 PGFV+T++ + + ++ L + L R E E+A FL ++ Y+ G + G Sbjct: 183 CPGFVNTEILQTVPDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVNGVAIEASG 242 Query: 232 GLQL 235 G+ L Sbjct: 243 GMSL 246 >1H5Q-A nrPDB Length = 265 Score = 107 bits (266), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 82/254 (32%), Positives = 125/254 (49%), Gaps = 18/254 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARN----LEGAKAAAGDLGGDHLAFSCD 56 ++K V GG+RGIG A + +A G +AVI R+ +E + + G A+ CD Sbjct: 13 VNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCD 72 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 V+ V T ++++ LG ++ L+ AG++ ED N+ G TC+ Sbjct: 73 VSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCR 132 Query: 117 AAMRTMIQ-QQGGSIVNVGSIVG-------LKGNSGQSVYSASKGGLVGFSRALAKEVAR 168 A + +Q QQ GSIV S+ L G+ Q Y++SK + LA E A Sbjct: 133 AVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEWAS 192 Query: 169 KKIRVNVVAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYIT 223 IRVN ++PG+V+TD T + + +H NIPL RF + E+ + LL + Y+T Sbjct: 193 AGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDHATYMT 252 Query: 224 GHVLVVDGGLQLIL 237 G +DGG QLI Sbjct: 253 GGEYFIDGG-QLIW 265 >1E3W-A nrPDB Length = 261 Score = 107 bits (266), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 125/252 (49%), Gaps = 24/252 (9%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVI-ARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 V + GG+ G+G + A+ + +G ++ N EG + A LGG+ + +V E + Sbjct: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-ETEAKKLGGNCIFAPANVTSEKE 70 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRT---------KTEDMVSQLHTNLLGSML 113 VQ ++ GR++ VN AGI + ++T ED ++ NL+G+ Sbjct: 71 VQAALTLAKEKFGRIDVAVNCAGI---AVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 Query: 114 TCKAAMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVA 167 + M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A Sbjct: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 Query: 168 RKKIRVNVVAPGFVHTDMTKDLKE---EHLKKNIPL-GRFGETIEVAHAVVFLLESPYIT 223 IRV +APG T + L + L +P R G+ E AH V ++E+P++ Sbjct: 188 PIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLN 247 Query: 224 GHVLVVDGGLQL 235 G V+ +DG +++ Sbjct: 248 GEVIRLDGAIRM 259 >1GEG-A nrPDB Length = 256 Score = 105 bits (262), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/254 (31%), Positives = 127/254 (50%), Gaps = 22/254 (8%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDV 57 M KV V G +GIG+A+A + + G+ +A+ N AKA A ++ GG +A DV Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHT-NLLGSMLTCK 116 + V E+ K LG + +VN AG+ + + T ++V +++ N+ G + + Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGV-APSTPIESITPEIVDKVYNINVKGVIWGIQ 119 Query: 117 AAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 AA+ ++ GG I+N S G GN +VYS+SK + G ++ A+++A I VN Sbjct: 120 AAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNG 179 Query: 176 VAPGFVHTDMTKDLKEE--------------HLKKNIPLGRFGETIEVAHAVVFLL--ES 219 PG V T M ++ + K I LGR E +VA V +L +S Sbjct: 180 YCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDS 239 Query: 220 PYITGHVLVVDGGL 233 Y+TG L++DGG+ Sbjct: 240 DYMTGQSLLIDGGM 253 >1O5I-A nrPDB Length = 249 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 76/238 (31%), Positives = 118/238 (49%), Gaps = 18/238 (7%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 DK V SRGIGRAVA +++++G + + ARN E K + H CD+ K+ Sbjct: 19 DKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSG------HRYVVCDLRKDL 72 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 D+ FE++++ V+ LV AG + G ED + + L + + + Sbjct: 73 DL--LFEKVKE----VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPA 126 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M ++ G IV + S + ++++ L GF + L+ EVA I VN VAPG+ Sbjct: 127 MKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWT 186 Query: 182 HTDMTKDLKEEHLKK----NIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 T+ K+L E KK IP+ R + E+A V FL ++ Y+TG +VVDGGL Sbjct: 187 ETERVKELLSEEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVDGGL 244 >3V2G-A nrPDB Length = 271 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 77/239 (32%), Positives = 120/239 (50%), Gaps = 11/239 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL-EGAKAAAGDL---GGDHLAFSCDVA 58 K V GGSRGIG A+A+ +A +G +A+ N E A+A ++ GG +A D Sbjct: 32 KTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIRADNR 91 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 ++ E + LG ++ LVN+AGI L T D + N + ++A Sbjct: 92 DAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFVAIRSA 151 Query: 119 MRTMIQQQGGSIVNVGS-IVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 R + GG I+ +GS + L G S+YSASK L G ++ LA+++ + I VN+V Sbjct: 152 SRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGITVNIVH 209 Query: 178 PGFVHTDMTKDLKE--EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 PG TDM + E ++ I G +GE ++A V +L + ++TG L +DGG Sbjct: 210 PGSTDTDMNPADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQGKFVTGASLTIDGG 268 >5ITV-A nrPDB Length = 255 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 77/248 (31%), Positives = 121/248 (48%), Gaps = 20/248 (8%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA--GDLGGDHLAF-SCDVA 58 DK + GG+ GIG A Q A G + V+ +++ A+ A D L F D+ Sbjct: 7 DKTVLITGGASGIGYAAVQ--AFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDIT 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E Q+ E G ++ L+N AGI + + D L NL G L K A Sbjct: 65 DEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHA 124 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 ++ M+ G+I+N S+ GL Y+ASKGG++ ++++A + A+ +IRVN V P Sbjct: 125 LKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCP 184 Query: 179 GFVHTDMT------------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITG 224 G + T + +++K+E K N PL R G+ E+A+ ++FL S Y+TG Sbjct: 185 GIIDTPLNEKSFLENNEGTLEEIKKEKAKVN-PLLRLGKPEEIANVMLFLASDLSSYMTG 243 Query: 225 HVLVVDGG 232 + DGG Sbjct: 244 SAITADGG 251 >2B4Q-A nrPDB Length = 276 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 122/248 (49%), Gaps = 16/248 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKE 60 ++ V GGSRGIG+ +AQ + G R+ + AR+ E A L GD A D++ E Sbjct: 30 RIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLSSE 89 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 + + L + R++ LVN AG + L + N+ S+ +C + Sbjct: 90 AGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVT-SVFSCIQQLL 148 Query: 121 TMIQQQGGS-----IVNVGSIVGLKGNSGQS-VYSASKGGLVGFSRALAKEVARKKIRVN 174 ++++ + ++N+GS+ G+ Q+ Y SK L SR LAKE+ + I VN Sbjct: 149 PLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVGEHINVN 208 Query: 175 VVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLES--PYITGHVL 227 V+APG + MT+ + E +IP+GR+G E+A + L + Y+TG+V+ Sbjct: 209 VIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAGAYMTGNVI 268 Query: 228 VVDGGLQL 235 +DGG L Sbjct: 269 PIDGGFHL 276 >3AUT-A nrPDB Length = 269 Score = 101 bits (252), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 120/244 (49%), Gaps = 12/244 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE----GAKAAAGDLGGDHLAFSCDV 57 DKV + GGS G+GRA+A ++ ++ + N E AK + GG + DV Sbjct: 15 DKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQGDV 74 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 KE DV N + K G ++ ++N AG+ ++ + TNL G+ L + Sbjct: 75 TKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGSRE 134 Query: 118 AMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A++ ++ G+++N+ S+ + Y+ASKGG+ + LA E A K IRVN + Sbjct: 135 AIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNI 194 Query: 177 APGFVHTDMTKD-----LKEEHLKKNIPLGRFGETIEVAHAVVFLLES--PYITGHVLVV 229 PG ++T + + ++ ++ IP+G G+ EVA FL S Y+TG L Sbjct: 195 GPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFA 254 Query: 230 DGGL 233 DGG+ Sbjct: 255 DGGM 258 >3UN1-A nrPDB Length = 260 Score = 100 bits (249), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 114/236 (48%), Gaps = 16/236 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV + G S+GIG + + + YR+ +R+++ + D + D++K Sbjct: 29 KVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSADP------DIHTVAGDISKPET 82 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 E + GR++ LVN AG+ V ED L N+ G + A M Sbjct: 83 ADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAEM 142 Query: 123 IQQQGGSIVNVGS------IVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 ++Q G IV++ + +VG+ ++ S +KGGL +R+LA E +R +RVN V Sbjct: 143 LKQGSGHIVSITTSLVDQPMVGMP----SALASLTKGGLNAVTRSLAMEFSRSGVRVNAV 198 Query: 177 APGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGG 232 +PG + T M L P+GR GE +V AV++L + +ITG +L VDGG Sbjct: 199 SPGVIKTPMHPAETHSTLAGLHPVGRMGEIRDVVDAVLYLEHAGFITGEILHVDGG 254 >1DOH-A nrPDB Length = 283 Score = 100 bits (249), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 25/253 (9%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAK---AAAGDLGGDHLAFSCDVA 58 KV V G RGIGR +A + R+G ++ V A + E A+ AA G D +V Sbjct: 30 KVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVG 89 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 D+ FEE K G+++ + + +G+ G + E+ N G + A Sbjct: 90 VVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREA 149 Query: 119 MRTMIQQQGGSIVNVGSIVG-LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + + + GG ++ +GSI G K +VYS SKG + F+R +A ++A KKI VNVVA Sbjct: 150 YKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITVNVVA 207 Query: 178 PGFVHTDMTKDLKEEHLK--KNI--------------PLGRFGETIEVAHAVVFLLESP- 220 PG + TDM + E++ +N+ PL R G I++A V FL + Sbjct: 208 PGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLASNDG 267 Query: 221 -YITGHVLVVDGG 232 ++TG V+ +DGG Sbjct: 268 GWVTGKVIGIDGG 280 >3UF0-A nrPDB Length = 273 Score = 100 bits (248), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 80/246 (32%), Positives = 114/246 (46%), Gaps = 22/246 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA---GDLGGDHLAFSCDVAK 59 + V G GIGRA+A AR G + R +G K A D GG A D+A Sbjct: 32 RTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-DGVKEVADEIADGGGSAEAVVADLAD 90 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMV-----SQLHTNLLGSMLT 114 N EEL RV+ LVN AGI + R E++ L NL + + Sbjct: 91 LEGAANVAEELAATR-RVDVLVNNAGI-----IARAPAEEVSLGRWREVLTVNLDAAWVL 144 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 ++ M+ G IV + S++ +G + Y+ASK +VG +RALA E A + + VN Sbjct: 145 SRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVN 204 Query: 175 VVAPGFVHTDMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 227 +APG+V T T L+ + + IP GR+ ++ VFL + Y+ G VL Sbjct: 205 ALAPGYVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDAASYVHGQVL 264 Query: 228 VVDGGL 233 VDGG Sbjct: 265 AVDGGW 270 >2ZAT-A nrPDB Length = 260 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/242 (30%), Positives = 125/242 (51%), Gaps = 11/242 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS---CDVA 58 +KV V + GIG A+A+ +A+ G + V +R E L G+ L+ + C V Sbjct: 14 NKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVG 73 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ-LHTNLLGSMLTCKA 117 K D + G V+ LV+ A +N + TE++ + LH N+ ++L KA Sbjct: 74 KAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKA 133 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + M ++ GGS++ V S+ Y+ SK L+G ++ LA E+A + IRVN +A Sbjct: 134 VVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLA 193 Query: 178 PGFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVD 230 PG + T+ ++ L ++E++K+++ + R G + A V FL ++ YITG +VV Sbjct: 194 PGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVVVG 253 Query: 231 GG 232 GG Sbjct: 254 GG 255 >3U5T-A nrPDB Length = 267 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 81/246 (32%), Positives = 122/246 (49%), Gaps = 20/246 (8%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL-------GGDHLAFS 54 +KV V G SRGIG A+A +A G+ + + N G AAA ++ GG L Sbjct: 27 NKVAIVTGASRGIGAAIAARLASDGFTVVI---NYAGKAAAAEEVAGKIEAAGGKALTAQ 83 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 DV+ V+ F E+ G V+ LVN AGI + T + NL G+ T Sbjct: 84 ADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNT 143 Query: 115 CKAAMRTMIQQQGGSIVNVG-SIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 + A + + + GG I+N+ S VGL S +Y+A+K G+ + L+KE+ + I V Sbjct: 144 LREAAQRL--RVGGRIINMSTSQVGLLHPS-YGIYAAAKAGVEAMTHVLSKELRGRDITV 200 Query: 174 NVVAPGFVHTDMTKDLKEEHLK----KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVL 227 N VAPG TD+ + K + ++ K PL R G ++A AV FL + ++ G VL Sbjct: 201 NAVAPGPTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNGQVL 260 Query: 228 VVDGGL 233 +GG+ Sbjct: 261 RANGGI 266 >5JS6-A nrPDB Length = 274 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 70/228 (30%), Positives = 116/228 (50%), Gaps = 25/228 (10%) Query: 25 KGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAA 84 G R+ + ++ G +A +L G CDV +E DV+ E + GR++ +VN A Sbjct: 34 SGARVVICDKDESGGRALEQELPGAVFIL-CDVTQEDDVKTLVSETIRRFGRLDCVVNNA 92 Query: 85 GINRDGLLVRTKTEDMVSQ-----LHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139 G + + E+ +Q L NLLG+ K A+ + + QG +++N+ S+VG Sbjct: 93 GHHPP----PQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG-NVINISSLVGA 147 Query: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDL---------- 189 G + Y A+KG + ++ALA + + +RVN ++PG + T + ++L Sbjct: 148 IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRAT 207 Query: 190 -KEEHLKKNIPLGRFGETIEVAHAVVFLL-ESPYITGHVLVVDGGLQL 235 +E L + PLGR G+ EV A VFL E+ + TG L+V GG +L Sbjct: 208 IREGMLAQ--PLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAEL 253 >2EW8-A nrPDB Length = 249 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/240 (29%), Positives = 113/240 (47%), Gaps = 8/240 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDLGGDHLAFSCDVAKE 60 DK+ + GG+ GIGRA+A+ A +G +A+ A+AA +LG L CDV++ Sbjct: 7 DKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDVSQP 66 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 DV+ +++ GR + LVN AGI E N+ L KA + Sbjct: 67 GDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMAKAFVP 126 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 M + G I+N+ S + Y ++K +GF+RALA ++ + I VN +AP Sbjct: 127 GMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAIAPSL 186 Query: 181 VHTDMTKDLKEEHLKKNIP-----LGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 V T T+ + +P + R +++ A FL ++ +ITG L VDGG+ Sbjct: 187 VRTATTEASALSAMFDVLPNMLQAIPRLQVPLDLTGAAAFLASDDASFITGQTLAVDGGM 246 >3PPI-A nrPDB Length = 281 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 78/241 (32%), Positives = 114/241 (47%), Gaps = 17/241 (7%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V GG+ G+G A + + G + + E KA A +LG S +V E V Sbjct: 35 VSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSVLAA 94 Query: 67 FEELEKHLGRVNFLVNAAG--------INRDGLLVR----TKTEDMVSQLHTNLLGSMLT 114 E LGR+ + V A G + RDG TKT D+ N+ + Sbjct: 95 IEA-ANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNGTYNVARLVAA 153 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 AA + G++V SI G +G GQ+ Y+A+K G++G + A A++++ IRVN Sbjct: 154 SIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAARDLSSAGIRVN 213 Query: 175 VVAPGFVHTDMTKDLKEEHLKK---NIPLG-RFGETIEVAHAVVFLLESPYITGHVLVVD 230 +APG + T + + + EE L K NIP R G E A A FLL + YI G V+ +D Sbjct: 214 TIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFADAAAFLLTNGYINGEVMRLD 273 Query: 231 G 231 G Sbjct: 274 G 274 >4HP8-A nrPDB Length = 247 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/237 (30%), Positives = 118/237 (49%), Gaps = 16/237 (6%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNL--EGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V G + G+G+A+A +A G + AR E A D GG+ A D A + Sbjct: 14 VTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKD-GGNASALLIDFADPLAAK 72 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 ++F + + LVN AGI R V D + NL T +A + ++ Sbjct: 73 DSFTD-----AGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKELLA 127 Query: 125 Q-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 + + G +VN+ S++ +G Y+A+K G+ G ++ LA E A K I VN +APG++ T Sbjct: 128 KGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYIET 187 Query: 184 DMTKDLKEEHLK-----KNIPLGRFGETIEVAHAVVFLLESP--YITGHVLVVDGGL 233 + T+ L+ + + + IP GR+G + ++A A VFL + Y+ G +L VDGG Sbjct: 188 NNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILNVDGGW 244 >1GEE-A nrPDB Length = 261 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 120/245 (48%), Gaps = 12/245 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD----LGGDHLAFSCDVA 58 KV + G S G+G+++A A + ++ V R+ E + + +GG+ +A DV Sbjct: 8 KVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVT 67 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E DV N + K G+++ ++N AG+ D + TNL G+ L + A Sbjct: 68 VESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGSREA 127 Query: 119 MRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 ++ ++ G+++N+ S+ Y+ASKGG+ + LA E A K IRVN + Sbjct: 128 IKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIG 187 Query: 178 PGFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVD 230 PG ++T + + + ++ IP+G GE E+A +L E+ Y+TG L D Sbjct: 188 PGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEASYVTGITLFAD 247 Query: 231 GGLQL 235 GG+ L Sbjct: 248 GGMTL 252 >4Z9Y-A nrPDB Length = 253 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 76/244 (31%), Positives = 119/244 (48%), Gaps = 17/244 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAA---AGDLGGDHLAFSCDVAK 59 KV + G G+G+ +A +A+ G ++ N+ K LG L+ + D++ Sbjct: 11 KVALITGCDTGLGQGMAIGLAQAG--CDIVGVNIVEPKDTIEKVTALGRRFLSLTADMSN 68 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINR--DGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 E+ G V+ LVN AGI R D + K D V L N+ + Sbjct: 69 VSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNL--NIKSVFFMSQT 126 Query: 118 AMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 R I+Q +GG I+N+ S++ +G Y+ASK ++G +R +A E A+ I VN + Sbjct: 127 VARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNAI 186 Query: 177 APGFVHTDMTKDLK--EEHLKK---NIPLGRFGETIEVAHAVVFLLESP--YITGHVLVV 229 APG++ T+ T+ L+ EE K+ IP GR+G ++ VFL S YI G+ + V Sbjct: 187 APGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYINGYTIAV 246 Query: 230 DGGL 233 DGG Sbjct: 247 DGGW 250 >3U4C-A nrPDB Length = 281 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 66/249 (26%), Positives = 114/249 (45%), Gaps = 25/249 (10%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH-----LAFSCDVAKEH 61 V G S+GIG+A+A +A + + L + +RNL+ ++ D+ H + + D++ +H Sbjct: 28 VMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMSDQH 87 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 F+++E GR++ L+N EDM + + + K A Sbjct: 88 TRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDAIKRASSL 147 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSAS--KGGLVGFSRALAKEVARKKIRVNVVAPG 179 M Q + G I+N+ + L G ++++ S L+ S+ ++ ++A I VN + PG Sbjct: 148 MKQNEFGRIINI--VGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVNCLNPG 205 Query: 180 FVHTD--------------MTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYIT 223 F+ TD ++K EE + IP+ R G E A FL E+ YIT Sbjct: 206 FIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEEASYIT 265 Query: 224 GHVLVVDGG 232 G + DGG Sbjct: 266 GQQISADGG 274 >1NFF-A nrPDB Length = 260 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 77/232 (33%), Positives = 113/232 (48%), Gaps = 4/232 (1%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V GG+RG+G + + M +G ++ E KA A +L DV + Sbjct: 8 KVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVTQPAQ 67 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + + G ++ LVN AGI G + + L NL G L +A ++ M Sbjct: 68 WKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRAVVKPM 127 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 + GSI+N+ SI GL G Y+A+K + G +++ A E+ IRVN + PG V Sbjct: 128 KEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHPGLVK 187 Query: 183 TDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 T MT + E+ + LGR E +EV++ VV+L ES Y TG VVDGG Sbjct: 188 TPMTDWVPEDIFQT--ALGRAAEPVEVSNLVVYLASDESSYSTGAEFVVDGG 237 >4TRR-A nrPDB Length = 269 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 123/252 (48%), Gaps = 21/252 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 K V G + GIG+ +A +A+ G +A+ N +GA A A ++ GG + + DV Sbjct: 15 KTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMDVTN 74 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 E V +++ + G V+ LV+ AGI + D ++ G+ LT KAA+ Sbjct: 75 EEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTTKAAL 134 Query: 120 RTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M + +GG ++ +GS+ + + +S Y +K GL+G +R LAKE A+ +R +VV P Sbjct: 135 KHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSHVVCP 194 Query: 179 GFVHTDMTKD----------LKEEHLKKNIPLGR-----FGETIEVAHAVVFL--LESPY 221 GFV T + + EE + K + LG F +VA V+FL S Sbjct: 195 GFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLSAFPSAA 254 Query: 222 ITGHVLVVDGGL 233 +TG +V G Sbjct: 255 LTGQSFIVSHGW 266 >4FC7-A nrPDB Length = 277 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 74/249 (29%), Positives = 114/249 (45%), Gaps = 14/249 (5%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE----GAKAAAGDLGGDHLAFSCDV 57 DKV + GG GIG +A++ R G + +R+L A+ AG G L S DV Sbjct: 27 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 86 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 V ++ K GR++ L+N A N + + + G+ + Sbjct: 87 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 146 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + GG IVN+ + +G +G + Q ++K + +R LA E + IRVN +A Sbjct: 147 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 206 Query: 178 PGFVH-TDMTKDL--KEEHLKKNI---PLGRFGETIEVAHAVVFLLESP---YITGHVLV 228 PG + T+ + L + L + PL R G E+AH+V++ L SP Y+TG VLV Sbjct: 207 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY-LASPLASYVTGAVLV 265 Query: 229 VDGGLQLIL 237 DGG L Sbjct: 266 ADGGAWLTF 274 >1AE1-A nrPDB Length = 273 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/248 (29%), Positives = 122/248 (49%), Gaps = 27/248 (10%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARN---LEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V GGS+GIG A+ + +A G R+ +RN L+ + G + CD+ + Sbjct: 26 VTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTE- 84 Query: 64 QNTFEELEKHL--GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC-----K 116 ++ + H+ G++N LVN AG+ ++ + +D + + ++G+ + Sbjct: 85 RDKLMQTVAHVFDGKLNILVNNAGV-----VIHKEAKDFTEKDYNIIMGTNFEAAYHLSQ 139 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A + Q G+++ + SI G S+YSASKG + +++LA E A+ IRVN V Sbjct: 140 IAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSV 199 Query: 177 APGFVHTDM--TKDLKEEHLKKNI-------PLGRFGETIEVAHAVVFLL--ESPYITGH 225 APG + T + T K H K+ I P+GR G+ EV+ + FL + YITG Sbjct: 200 APGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYITGQ 259 Query: 226 VLVVDGGL 233 ++ DGG Sbjct: 260 IIWADGGF 267 >3OIC-A nrPDB Length = 258 Score = 91.3 bits (225), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 121/249 (48%), Gaps = 15/249 (6%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGD---LGGDHLAFSCDV 57 +K V G SRG+G+A A +A GY + + AR+ + A A + LG L +V Sbjct: 4 NKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANV 63 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVN--AAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 + ++ F+++++ GR++ VN A+G+ R + + D ++ L + Sbjct: 64 GQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKAL--LFCA 121 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + A + M + GG IV++ S+ ++ + SK L +R LA E++ K+I VN Sbjct: 122 QEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNA 181 Query: 176 VAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLESP--YITGHVLV 228 V+ G + TD K E ++N P GR E ++ V FL+ S I G ++ Sbjct: 182 VSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTII 241 Query: 229 VDGGLQLIL 237 VDGG L++ Sbjct: 242 VDGGRSLLV 250 >5IZ4-A nrPDB Length = 271 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 73/258 (28%), Positives = 115/258 (44%), Gaps = 29/258 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG------DLGGDHLAFSCD 56 VC + G + GIG A A A+ G+ +A+ + AA+ D G L F D Sbjct: 15 PVCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDAD 74 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH------TNLLG 110 V K+ D ++ + + R++ L+N AG R ++ D + NL+G Sbjct: 75 VGKDADCRHAVDMVASRWQRIDALINCAGTTR---VIPHNAFDQIDDFEFERVYRVNLIG 131 Query: 111 SMLTCKAAMRTMIQQ----QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 +AA+ + + + S+VNV S+ GL G Y+ASKG + + +LA+ + Sbjct: 132 LYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNL 191 Query: 167 ARKKIRVNVVAPGFVHTDM--------TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL- 217 A IRVN +APG V + D + ++ PL R E+A FL Sbjct: 192 A-PHIRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLTA 250 Query: 218 ESPYITGHVLVVDGGLQL 235 +P ITG V+ + GL L Sbjct: 251 HAPAITGQVIAAENGLLL 268 >3WYE-A nrPDB Length = 256 Score = 90.9 bits (224), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 121/253 (47%), Gaps = 20/253 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDV 57 M KV V G +GIG+A+A + + G+ +A+ N AKA A ++ GG +A DV Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + V E+ K LG + +VN AGI + L+ ED+ N+ +A Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 120 Query: 118 AMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A+ ++ GG I+N SI ++G S YS +K + G ++ A+++A I VN Sbjct: 121 AVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 177 APGFVHTDMTKDLKEEHLKKN--------------IPLGRFGETIEVAHAVVFLL--ESP 220 PG V T M + + E K N I LGR +VA V FL +S Sbjct: 181 CPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSD 240 Query: 221 YITGHVLVVDGGL 233 Y+TG L++DGG+ Sbjct: 241 YMTGQSLLIDGGM 253 >4CR6-A nrPDB Length = 271 Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 75/249 (30%), Positives = 117/249 (46%), Gaps = 16/249 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G + GIGRA + R+G +V+A +L AA + +CD+A Sbjct: 16 KAAIVTGAAGGIGRATVEAYLREG--ASVVAMDLAPRLAATRYEEPGAIPIACDLADRAA 73 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINR-DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + + LG ++ LV + G + D + N+ G+ LTC+A R Sbjct: 74 IDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAGARA 133 Query: 122 MIQQQGGS------IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 M+ G I+ +GS+ + Y A+KGG+ +RA+A ++AR I VN+ Sbjct: 134 MVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGILVNM 193 Query: 176 VAPGFV-----HTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLV 228 +APG V +T ++ E + + LGR G EVA A VFL E S +ITG + Sbjct: 194 IAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAEDGSSFITGSTIT 253 Query: 229 VDGGLQLIL 237 +DGGL ++ Sbjct: 254 IDGGLSAMI 262 >3WTC-A nrPDB Length = 262 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 76/259 (29%), Positives = 125/259 (48%), Gaps = 36/259 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGY----------RLAVIARNLEGAKAAAGDLGGDHLA 52 K+ AV G ++GIG+A+A +A+ G LA A+ +E LG +A Sbjct: 9 KIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEA-------LGRRAVA 61 Query: 53 FSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112 + D++ ++T + K LG ++ +VN AGI + ++ + ++ N+ G + Sbjct: 62 LTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVL 121 Query: 113 LTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK 170 +AA T+ +++G G I+N SI G +G YSA+K + +++ AKE+A Sbjct: 122 WGMQAAA-TLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSG 180 Query: 171 IRVNVVAPGFVHTDM--TKDLKEEHLK------------KNIPLGRFGETIEVAHAVVFL 216 I VN PG V TDM T D + + + I LGR +VA V +L Sbjct: 181 ITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYL 240 Query: 217 LES--PYITGHVLVVDGGL 233 S Y+TG +++DGGL Sbjct: 241 SSSDADYMTGQSVLIDGGL 259 >2FWM-X nrPDB Length = 250 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 65/195 (33%), Positives = 91/195 (46%), Gaps = 15/195 (7%) Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 DVA V + L R++ LVNAAGI R G + ED N+ G+ Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 113 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + M +Q+GG+IV V S G S Y ASK L + ++ E+A +R NV Sbjct: 114 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 173 Query: 176 VAPGFVHTDMTK------DLKE-------EHLKKNIPLGRFGETIEVAHAVVFLLE--SP 220 V+PG TDM + D +E E K IPLG+ E+A+ ++FL + Sbjct: 174 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 233 Query: 221 YITGHVLVVDGGLQL 235 +IT +VVDGG L Sbjct: 234 HITLQDIVVDGGSTL 248 >2AG5-A nrPDB Length = 246 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 63/222 (28%), Positives = 107/222 (48%), Gaps = 28/222 (12%) Query: 37 EGAKAAAGDLGGDHL----------AFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGI 86 EGAK A D+ L DV K+ + E+E R++ L N AG Sbjct: 29 EGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVE----RLDVLFNVAGF 84 Query: 87 NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVG-LKGNSGQ 145 G ++ + +D ++ N+ L KA + M+ Q+ G+I+N+ S+ +KG + Sbjct: 85 VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNR 144 Query: 146 SVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM----------TKDLKEEHLK 195 VYS +K ++G ++++A + ++ IR N V PG V T ++ + + LK Sbjct: 145 CVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLK 204 Query: 196 KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 + GRF E+A V+L ES Y+TG+ +++DGG L Sbjct: 205 RQ-KTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 >2AE2-A nrPDB Length = 260 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 72/241 (29%), Positives = 110/241 (45%), Gaps = 14/241 (5%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARN---LEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V GGSRGIG + + +A G + +RN L G A CD++ + Sbjct: 14 VTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCDLSSRSER 73 Query: 64 QNTFEELEKHL-GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 Q + H G++N LVN AGI ED + N + A + Sbjct: 74 QELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLSVLAHPFL 133 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 + G++V + S+ G ++VY A+KG + +R LA E A+ IRVN V PG + Sbjct: 134 KASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNGVGPGVIA 193 Query: 183 TDMTK-DLKEEHLKKNI-------PLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 T + + +++ K+N+ L R GE E+A V FL + Y+TG ++ VDGG Sbjct: 194 TSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASYVTGQIIYVDGG 253 Query: 233 L 233 L Sbjct: 254 L 254 >5OJG-A nrPDB Length = 260 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 115/247 (46%), Gaps = 15/247 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA----FSCDVA 58 KV V ++GIG A+A+ + +G + + +RN + A L L + +A Sbjct: 11 KVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIA 70 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 D + + + G++N LVN GIN G ++ + N+ K Sbjct: 71 STDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKL 130 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + ++ GG+I+ S K G + Y +K LVG +RALA +A+ IRVN +A Sbjct: 131 VHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIA 190 Query: 178 PGFVHTDMTKDL--------KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVL 227 PG + T M++ L KE + I LGR G + A V +L +S YITG ++ Sbjct: 191 PGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMI 250 Query: 228 VVDGGLQ 234 ++ GG+Q Sbjct: 251 IIAGGVQ 257 >5JY1-A nrPDB Length = 274 Score = 87.0 bits (214), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 9/200 (4%) Query: 45 DLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ- 103 ++GG L DV + ++ + G ++ LVN A + +L+ KT++M+ Q Sbjct: 60 EMGGRSLFVKTDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQT 119 Query: 104 LHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALA 163 L T+L + +AA M +++ G IVN SI G Y+ +K G+VG +R+ A Sbjct: 120 LTTSLWATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAA 179 Query: 164 KEVARKKIRVNVVAP---GFVHTDMTKDLKE--EHLKKNIPLGRFGET-IEVAHAVVFLL 217 E R I VN +AP G ++ E E PLGR G+ ++ A VF Sbjct: 180 SEWGRFNITVNAIAPTAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFA 239 Query: 218 E--SPYITGHVLVVDGGLQL 235 S ++TG L VDGGL L Sbjct: 240 SEMSRFVTGETLHVDGGLHL 259 >1X1T-A nrPDB Length = 260 Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 116/253 (45%), Gaps = 22/253 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV----IARNLEGAKAA-AGDLGGDHLAFSCDV 57 KV V G + GIG +A +A +G + + A +E +A A G L D+ Sbjct: 5 KVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDGADL 64 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 +K V+ + + +GR++ LVN AGI L+ TE + L NL A Sbjct: 65 SKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHGTAA 124 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A+ M +Q G I+N+ S GL ++ +S Y A+K G+VGF++ A E A + I N + Sbjct: 125 ALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITANAIC 184 Query: 178 PGFVHTDMTKD----LKE-----------EHLKKNIPLGRFGETIEVAHAVVFLLE--SP 220 PG+V T + + L E E L + P +F ++ VFL + Sbjct: 185 PGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLASDAAA 244 Query: 221 YITGHVLVVDGGL 233 ITG + VDGG Sbjct: 245 QITGTTVSVDGGW 257 >3RWB-A nrPDB Length = 247 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/239 (29%), Positives = 114/239 (47%), Gaps = 9/239 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G ++GIG+A+A +A G + V N EGAKAAA +G A + D++ Sbjct: 7 KTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPGS 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 V+ F E++ G ++ LVN A I + + NL G+ + +A M Sbjct: 67 VKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRAGTDQM 126 Query: 123 -IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 + G ++++ S G + Y A+KGG++GF+RALA E+ + I N V PG + Sbjct: 127 RAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAVTPGLI 186 Query: 182 HTDMTKDLKEEHLKKNIPL-----GRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 +D K + + G+ G+ +A V FL ++ +ITG L VD G+ Sbjct: 187 ESDGVKASPHNEAFGFVEMLQAMKGK-GQPEHIADVVSFLASDDARWITGQTLNVDAGM 244 >3T7C-A nrPDB Length = 299 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 83/270 (30%), Positives = 125/270 (46%), Gaps = 43/270 (15%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI--ARNLEGAK---AAAGDL----------G 47 KV + G +RG GR+ A +AR+G + I + L+G K + DL G Sbjct: 29 KVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALG 88 Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNF-LVNAAGINRDGLLVRTKTEDMVSQLHT 106 +A DV +Q ++ LGR++ L NAA + L R + + Sbjct: 89 RRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMIDV 148 Query: 107 NLLGSMLTCKAAM-RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 NL G+ +T + A+ M ++GGSIV SI GL+G Y ASK GL G R +A E Sbjct: 149 NLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMALE 208 Query: 166 VARKKIRVNVVAPGFVHTDM----------TKDLKEEHLKK-----------NIPLGRFG 204 + + IRVN+V P V T M DL+ ++ IP + Sbjct: 209 LGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIP---YV 265 Query: 205 ETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 E ++++A++FL+ ++ YITG L VDGG Sbjct: 266 EPADISNAILFLVSDDARYITGVSLPVDGG 295 >3OML-A nrPDB Length = 613 Score = 84.0 bits (206), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 68/192 (35%), Positives = 95/192 (49%), Gaps = 23/192 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL------EGAKAAAGDL--------GG 48 +V V G G+GR A L A +G + V+ +L +GA A D+ GG Sbjct: 20 RVAVVTGAGAGLGREYALLFAERGAK--VVVNDLGGTHSGDGASQRAADIVVDEIRKAGG 77 Query: 49 DHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED--MVSQLHT 106 + +A D D E K GRV+ LVN AGI RD LV+T +D +V+ +H Sbjct: 78 EAVA---DYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVH- 133 Query: 107 NLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 L GS +AA M +Q G I+ S G+ GN GQ Y+A+K GL+G + +A E Sbjct: 134 -LKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEG 192 Query: 167 ARKKIRVNVVAP 178 AR + NV+ P Sbjct: 193 ARNNVLCNVIVP 204 >3R3S-A nrPDB Length = 294 Score = 84.0 bits (206), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 115/248 (46%), Gaps = 17/248 (6%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAV-----IARNLEGAKAAAGDLGGDHLAFSCD 56 D+ V GG GIGRA A AR+G +A+ + + KA + G + D Sbjct: 49 DRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLLPGD 108 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ-LHTNLLGSMLTC 115 ++ E ++ + + LG ++ L AG ++ T + Q N+ Sbjct: 109 LSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFWIT 168 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + A+ + +G SI+ SI + + Y+A+K ++ +SR LAK+VA K IRVN+ Sbjct: 169 QEAIPLL--PKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNI 226 Query: 176 VAPGFVHTDM------TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVL 227 VAPG + T + T+D K + P+ R G+ E+A V+L ES Y+T V Sbjct: 227 VAPGPIWTALQISGGQTQD-KIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVH 285 Query: 228 VVDGGLQL 235 V GG L Sbjct: 286 GVCGGEHL 293 >3A28-C nrPDB Length = 258 Score = 83.2 bits (204), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 81/256 (31%), Positives = 120/256 (46%), Gaps = 24/256 (9%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG----DLGGDHLAF-SC 55 M KV V GG++GIGR +++ +A G+ +AV + +AA + F Sbjct: 1 MSKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGL 60 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 DV + + + +E + LG + LVN AGI + L+ ED+ N+ Sbjct: 61 DVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGI 120 Query: 116 KAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +AA R + G G I+N SI ++G S YS +K + G ++A A+E+A K V Sbjct: 121 QAASRKF-DELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTV 179 Query: 174 NVVAPGFVHTDMTKDLKEEHLKKN--------------IPLGRFGETIEVAHAVVFLLE- 218 N APG V T M + + E K N I LGR +VA V FL Sbjct: 180 NAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASE 239 Query: 219 -SPYITGHVLVVDGGL 233 S Y+TG V++VDGG+ Sbjct: 240 NSNYVTGQVMLVDGGM 255 >3ZV3-A nrPDB Length = 281 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 73/252 (28%), Positives = 117/252 (46%), Gaps = 23/252 (9%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 +V + GG+ G+GRA+ +G R+AV+ ++ E + GG+ + DV D Sbjct: 6 EVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVRSLQD 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ-----LHTNLLGSMLTCKA 117 + E G+++ L+ AGI + ED + H N+ G + KA Sbjct: 66 QKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYIHAVKA 125 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + ++ + GS+V S G N G +Y+A+K +VG R +A E+A +RVN VA Sbjct: 126 CLPALVSSR-GSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELA-PHVRVNGVA 183 Query: 178 PGFVHTDM----TKDLKEEH---------LKKNIPLGRFGETIEVAHAVVFLL---ESPY 221 PG ++TD+ + L E+ LK +P+GR E A VF +S Sbjct: 184 PGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFATRGDSLP 243 Query: 222 ITGHVLVVDGGL 233 TG +L DGG+ Sbjct: 244 ATGALLNYDGGM 255 >3D3W-A nrPDB Length = 244 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 73/240 (30%), Positives = 105/240 (43%), Gaps = 21/240 (8%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ-N 65 V G +GIGR Q + G R+ ++R DL D L C + V Sbjct: 12 VTGAGKGIGRGTVQALHATGARVVAVSRT-------QADL--DSLVRECPGIEPVCVDLG 62 Query: 66 TFEELEKHLGRV---NFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 +E E+ LG V + LVN A + + E NL + + R + Sbjct: 63 DWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGL 122 Query: 123 IQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 I + G+IVNV S + + SVY ++KG L ++ +A E+ KIRVN V P V Sbjct: 123 IARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVV 182 Query: 182 HTDM-----TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 T M + K + + IPLG+F E V +A++FLL S TG L V+GG Sbjct: 183 MTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFW 242 >3UVE-A nrPDB Length = 286 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 125/273 (45%), Gaps = 45/273 (16%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL-EGAKAAAGDLG-----GDHLAFSCD 56 KV V G +RG GR+ A +A++G +IA ++ + +A D + LA + D Sbjct: 12 KVAFVTGAARGQGRSHAVRLAQEGAD--IIAVDICKPIRAGVVDTAIPASTPEDLAETAD 69 Query: 57 VAKEHDVQNTFEELE---------------KHLGRVNFLVNAAGINRDG-LLVRTKTEDM 100 + K H+ + E++ + LGR++ +V AGI G L +T ED Sbjct: 70 LVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDW 129 Query: 101 VSQLHTNLLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFS 159 + NL G T KA + MI +GGSI+ S+ GLK Y A+K G+VG Sbjct: 130 TEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLM 189 Query: 160 RALAKEVARKKIRVNVVAPGFVHTDM----------TKDLKEEHLKKNIPLGR------- 202 RA E+ + IRVN V P V T M DL+ P+ + Sbjct: 190 RAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPI 249 Query: 203 -FGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 + E I++++AV+F E+ YITG L +D G Sbjct: 250 PWVEPIDISNAVLFFASDEARYITGVTLPIDAG 282 >2BGM-A nrPDB Length = 278 Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 68/223 (30%), Positives = 102/223 (45%), Gaps = 29/223 (13%) Query: 38 GAKAAAGDLGGDH-------------LAF-SCDVAKEHDVQNTFEELEKHLGRVNFLVNA 83 GAK D+ DH ++F CDV K+ DV+N + G+++ + Sbjct: 40 GAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGKLDIMFGN 99 Query: 84 AGI--NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKG 141 G+ ++ ED + N+ G+ L K A R MI + GSIV SI Sbjct: 100 VGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTASISSFTA 159 Query: 142 NSGQS-VYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDL-------KEE- 192 G S VY+A+K ++G + +L E+ IRVN V+P V + + D+ EE Sbjct: 160 GEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGVDSSRVEEL 219 Query: 193 -HLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 H N+ G +VA AV +L ES Y++G LV+DGG Sbjct: 220 AHQAANLK-GTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGG 261 >1HXH-A nrPDB Length = 253 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 70/243 (28%), Positives = 112/243 (46%), Gaps = 13/243 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V GG+ G+G V +L+ +G ++A N + A +LG + DV+ E D Sbjct: 7 KVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSSEAD 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 +++ LG +N LVN AGI G + + ED L N + C+ + M Sbjct: 67 WTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQGIAAM 126 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK--KIRVNVVAPGF 180 ++ GGSI+N+ S+ + YSASK + +RA A ++ IRVN + P Sbjct: 127 -KETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNSIHPDG 185 Query: 181 VHTDM-----TKDLKEEHLKKNIPLGRFGETI---EVAHAVVFLL--ESPYITGHVLVVD 230 ++T M K + +E + + L R G +A V+FL ES ++G L D Sbjct: 186 IYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDESSVMSGSELHAD 245 Query: 231 GGL 233 + Sbjct: 246 NSI 248 >3V8B-A nrPDB Length = 283 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 74/256 (28%), Positives = 122/256 (47%), Gaps = 24/256 (9%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 V + G GIGRA A +A G + + R + A ++ GG +A DV+ Sbjct: 29 PVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSD 88 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRT---KTEDMVSQLHTNLLGSMLTCK 116 E ++N +L G ++ +V AGIN G+ K + + NL G+ LT Sbjct: 89 ELQMRNAVRDLVLKFGHLDIVVANAGIN--GVWAPIDDLKPFEWDETIAVNLRGTFLTLH 146 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKG--NSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 + + Q+ GG+IV V SI G + G + Y+A+K V + LA E+ + IRVN Sbjct: 147 LTVPYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVN 206 Query: 175 VVAPGFVHTDMTKDLKEEH----------LKKNIPL--GRFGETIEVAHAVVFLLE--SP 220 V PG + T+++ + K H K +P+ G+ G + +VA + FL+ + Sbjct: 207 AVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERAR 266 Query: 221 YITGHVLVVDGGLQLI 236 ++TG + +DGG L+ Sbjct: 267 HVTGSPVWIDGGQGLL 282 >5ILO-A nrPDB Length = 271 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 68/199 (34%), Positives = 98/199 (49%), Gaps = 17/199 (8%) Query: 3 KVCAVFGGSRGIGRAVA-QLMARKGYRLAVI--ARNLEG-AKAAAGDLGGDHLAFSCDVA 58 K V GG+ GIG V+ QL+A ++A+I NLE K A + DVA Sbjct: 16 KNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVA 75 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + V+ T+EE+ K G ++ +VN AGI D + RT L NL G + + +A Sbjct: 76 NKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRT--------LLVNLGGIINSTLSA 127 Query: 119 MRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE--VARKKIRV 173 + M + GG +VN+ S+VGL VY A+K G++ F+R LA E R I+ Sbjct: 128 LPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKF 187 Query: 174 NVVAPGFVHTDMTKDLKEE 192 V PG TDM + E+ Sbjct: 188 VTVCPGATMTDMFTNFTEK 206 >3V2H-A nrPDB Length = 281 Score = 79.7 bits (195), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 115/258 (44%), Gaps = 28/258 (10%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK--------AAAGDLGGDHLA 52 M K + G + GIG A+A+ +A+ G A I N GA AG G L Sbjct: 24 MTKTAVITGSTSGIGLAIARTLAKAG---ANIVLNGFGAPDEIRTVTDEVAGLSSGTVLH 80 Query: 53 FSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112 D+ K ++ + + G + LVN AG+ + E + NL S Sbjct: 81 HPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSF 140 Query: 113 LTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 172 T + A+ M ++ G I+N+ S GL + +S Y A+K G++G ++ +A EVA + Sbjct: 141 HTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVT 200 Query: 173 VNVVAPGFVHTDM----------TKDLKEEHLKKNI-----PLGRFGETIEVAHAVVFLL 217 VN + PG+V T + T+ + EE + + P +F +VA ++L Sbjct: 201 VNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLA 260 Query: 218 --ESPYITGHVLVVDGGL 233 ++ ITG + +DGG Sbjct: 261 GDDAAQITGTHVSMDGGW 278 >5YSS-A nrPDB Length = 256 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 52/186 (27%), Positives = 90/186 (48%), Gaps = 1/186 (0%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDLGGDHLAFSCDVAKEH 61 K V G + GIG +AQ++A+ G L + +++ AK A G D++ E Sbjct: 6 KTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADLSDEA 65 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + + E G V+ L+N AGI + + + + NL T + A+ Sbjct: 66 QIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTRLALPG 125 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M + G I+N+ S+ GL + +S Y A+K G+VG ++ +A E A+ +I N + PG+V Sbjct: 126 MRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNALCPGWV 185 Query: 182 HTDMTK 187 T + + Sbjct: 186 LTPLVQ 191 >2Q2Q-A nrPDB Length = 255 Score = 77.8 bits (190), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 23/197 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYR------------LAVIARNLEGAKAAAGDLGGDH 50 K V G + GIG +AQ++AR G LA IAR+ G KA H Sbjct: 5 KTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARH--GVKAV------HH 56 Query: 51 LAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLG 110 A DVA+ ++ F E+ G V+ LVN AGI + + E + NL Sbjct: 57 PADLSDVAQ---IEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSA 113 Query: 111 SMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK 170 + A+ M + G I+N+ S+ GL G++G++ Y A+K G+VG ++ + E A Sbjct: 114 VFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSN 173 Query: 171 IRVNVVAPGFVHTDMTK 187 + N + PG+V T + + Sbjct: 174 VTCNAICPGWVLTPLVQ 190 >4DA9-A nrPDB Length = 280 Score = 77.4 bits (189), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 112/233 (48%), Gaps = 17/233 (7%) Query: 19 AQLMARKGYRLAVI----ARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHL 74 A+ +A G+ +A+ A + A LG + D+A Q T + + Sbjct: 46 ARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLADLSSHQATVDAVVAEF 105 Query: 75 GRVNFLVNAAGIN---RDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGG--- 128 GR++ LVN AGI RD L K E+ + + NL G++ +A ++ M+ Sbjct: 106 GRIDCLVNNAGIASIVRDDFL-DLKPENFDTIVGVNLRGTVFFTQAVLKAMLASDARASR 164 Query: 129 SIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKD 188 SI+N+ S+ + + + Y SK GL FS+ LA +A I V V PG + +DMT Sbjct: 165 SIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVFEVRPGIIRSDMTAA 224 Query: 189 L--KEEHLKKN--IPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 + K + L ++ +P+ R+GE ++ + V L + + TG V+ DGGL + Sbjct: 225 VSGKYDGLIESGLVPMRRWGEPEDIGNIVAGLAGGQFGFATGSVIQADGGLSI 277 >2X9N-A nrPDB Length = 288 Score = 77.0 bits (188), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 80/267 (29%), Positives = 130/267 (48%), Gaps = 45/267 (16%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARN-LEGAKAAAGDLGGD--HLAFSC--DVAKEH 61 V G ++ IGRA+A + + GYR+ + N E A + A +L + + A C D+ + Sbjct: 28 VTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSN 87 Query: 62 DVQNTFEEL----EKHLGRVNFLVNAAGI-------------NRDGLLVRTKTEDMVSQL 104 + + EE+ + GR + LVN A N +G V T+ +++ Sbjct: 88 VLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG-- 145 Query: 105 HTNLLGSMLTCKAAMRTMIQQQGG----------SIVNVGSIVGLKGNSGQSVYSASKGG 154 TN + L + Q+Q G SIVN+ + + S+Y+ K Sbjct: 146 -TNAIAPFLL----TMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHA 200 Query: 155 LVGFSRALAKEVARKKIRVNVVAPG--FVHTDMTKDLKEEHLKKNIPLGRFGETIE-VAH 211 LVG +++ A E+A IRVN VAPG + M ++ K++ +K +PLGR + E +A Sbjct: 201 LVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRK-VPLGRREASAEQIAD 259 Query: 212 AVVFLL--ESPYITGHVLVVDGGLQLI 236 AV+FL+ + YITG ++ VDGGL L+ Sbjct: 260 AVIFLVSGSAQYITGSIIKVDGGLSLV 286 >4EGF-A nrPDB Length = 266 Score = 76.6 bits (187), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 113/241 (46%), Gaps = 12/241 (4%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARN---LEGAKAAAGD-LGGDHLAFSCDVAKEHD 62 + G ++GIG +A+ A G RL + R+ L+ A+ A G+ G D + D+A+ Sbjct: 25 ITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVAIDLAEPDA 84 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + G ++ LVN AGI+ +V T + + + NL L A + M Sbjct: 85 PAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLASAVGKAM 144 Query: 123 IQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 + +GG+I+ V S L Y SK GLV ++ LA+E+ IR N V P V Sbjct: 145 VAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVCPTVV 204 Query: 182 HTDMTK-----DLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 T+M + + K + IPLGRF EV+ AVV+L + I G + VDGG Sbjct: 205 LTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVDIPVDGGYT 264 Query: 235 L 235 + Sbjct: 265 M 265 >5EJ2-A nrPDB Length = 308 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 122/273 (44%), Gaps = 49/273 (17%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI-----ARNLEGAKAAAGDLGGDHLAFSCDV 57 KV + G +RG GR+ A +A++G + I NL + DL A + D+ Sbjct: 38 KVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDL-----AETADL 92 Query: 58 AKEHDVQ--------NTFEELE-------KHLGRVNFLVNAAGINRDGLLVRTKTEDMVS 102 K+ D + FE L+ + LGR++ +V AG+ DG + K D V Sbjct: 93 VKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLH-KIRDNVW 151 Query: 103 Q--LHTNLLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFS 159 Q + NL G T KA + ++ +GGSIV S+ G K Y A+K G++G Sbjct: 152 QDMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLM 211 Query: 160 RALAKEVARKKIRVNVVAPGFVHTDMT----------KDLKEEHLKKNIPLGRFGETI-- 207 RA A E+ IRVN V P V T M DL+ P+ + T+ Sbjct: 212 RAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPV 271 Query: 208 ------EVAHAVVFLL--ESPYITGHVLVVDGG 232 ++++AV+FL ES Y+TG L VD G Sbjct: 272 PWVDASDISNAVLFLASDESRYVTGVSLPVDAG 304 >1BDB-A nrPDB Length = 277 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 113/248 (45%), Gaps = 23/248 (9%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 + GG+ G+GRA+ +G ++AV+ ++ E D G + L DV D + Sbjct: 10 ITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRSLEDQKQA 69 Query: 67 FEELEKHLGRVNFLVNAAGI-NRDGLLVRTKTEDMVSQ----LHTNLLGSMLTCKAAMRT 121 G+++ L+ AGI + LV E + + H N+ G + KA + Sbjct: 70 ASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHAVKACLPA 129 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 ++ +G I + S G N G +Y+A+K +VG R LA E+A +RVN V G + Sbjct: 130 LVASRGNVIFTI-SNAGFYPNGGGPLYTAAKHAIVGLVRELAFELA-PYVRVNGVGSGGI 187 Query: 182 HTDM---------TKDLKE----EHLKKNIPLGRFGETIEVAHAVVFLL---ESPYITGH 225 ++D+ +K + + LK +P+GR E E A VF ++ TG Sbjct: 188 NSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFATRGDAAPATGA 247 Query: 226 VLVVDGGL 233 +L DGGL Sbjct: 248 LLNYDGGL 255 >1AHH-A nrPDB Length = 255 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 110/243 (45%), Gaps = 13/243 (5%) Query: 1 MDKVCAVFGGS-RGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD---LGGDHLAFSCD 56 +D CA+ G+ GIG+ +A A G + V N + A + LGG A CD Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 + E ++ + LG+V+ LVN AG D N+ + Sbjct: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 M + GG I+ + S+ N + Y++SK R +A ++ K IRVN + Sbjct: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 Query: 177 APGFVHTDMTKDL----KEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YITGHVLVV 229 APG + TD K + E+ + ++ P+ R G+ ++A+A +FL SP +++G +L V Sbjct: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLC-SPAASWVSGQILTV 246 Query: 230 DGG 232 GG Sbjct: 247 SGG 249 >5O3Z-A nrPDB Length = 263 Score = 74.7 bits (182), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 66/255 (25%), Positives = 117/255 (45%), Gaps = 23/255 (9%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL-----GGDHLAFSC 55 M++V V GG + +G + + +A+ GY +AV N A A + G F Sbjct: 5 MEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKV 64 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 D E V+ +++ GR + LV +AG+ + + + + D L NL+G L Sbjct: 65 DATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCS 124 Query: 116 KAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 + + MI+ G I+ + S G G+ S YSA+K G VG +++LA ++A I V+ Sbjct: 125 REFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVH 184 Query: 175 VVAPG-FVHTDMTKDLKEEHLKK--------------NIPLGRFGETIEVAHAVVFLL-- 217 + G + + M + L ++ +K +PL R + +V + ++F Sbjct: 185 SLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASD 244 Query: 218 ESPYITGHVLVVDGG 232 ++ Y TG + V GG Sbjct: 245 KAAYCTGQSINVTGG 259 >4HBG-A nrPDB Length = 286 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 68/265 (25%), Positives = 108/265 (40%), Gaps = 52/265 (19%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS----CDVAK 59 V V G +RGIG+A+ Q + +KG ++ E + A D G S C +A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 60 EHDVQNTFEELEKHLG-------------------------------RVNFLVNAAGINR 88 + + + E + G VN L+N AG+ + Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 89 DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQG-----------GSIVNVGSIV 137 + L VRT + ++ N + + ++ M++ Q +IVN+ SI+ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 138 --GLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH-TDMTKDLK---E 191 G G SVYSASK L F+ LA E+ + IR ++PG V TDM ++L + Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 Query: 192 EHLKKNIPLGRFGETIEVAHAVVFL 216 E L++ I E+A V L Sbjct: 246 EMLERTIGASGTSAPAEIAEEVWSL 270 >3RKU-A nrPDB Length = 287 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 17/197 (8%) Query: 3 KVCAVFGGSRGIGRAVA--QLMARKG-YRLAVIARNLEGAKAAAGDLGGD------HLAF 53 K + G S GIG+A A L A G +L + AR LE + + + H+A Sbjct: 34 KTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVA- 92 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAG----INRDGLLVRTKTEDMVSQLHTNLL 109 D+ + ++ E L + ++ LVN AG +R G + TED+ TN+ Sbjct: 93 QLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIA---TEDIQDVFDTNVT 149 Query: 110 GSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK 169 + +A + + G IVN+GSI G S+Y ASK + F+ +L KE+ Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 170 KIRVNVVAPGFVHTDMT 186 KIRV ++APG V T+ + Sbjct: 210 KIRVILIAPGLVETEFS 226 >3UCF-A nrPDB Length = 223 Score = 73.6 bits (179), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 64/240 (26%), Positives = 108/240 (45%), Gaps = 33/240 (13%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V V GG+ GIG +A+ + + + V +R D++ E V Sbjct: 8 VYVVLGGTSGIGAELAKQLESEHTIVHVASRQT-----------------GLDISDEKSV 50 Query: 64 QNTFEELEKHLGRVNFLVNAAG-INRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + FE + G + L+ AG G +V + T G++L K R + Sbjct: 51 YHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGARYL 106 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 +QGGSI ++ K + V +A + ++ LAKE+A IRVN ++PG Sbjct: 107 --KQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELA--PIRVNAISPGLTK 162 Query: 183 TDMTK-------DLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQL 235 T+ K D + + ++P+G+ GE ++A A +F +++ Y+TG V+ VDGG L Sbjct: 163 TEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAYLFAIQNSYMTGTVIDVDGGALL 222 >1W73-A nrPDB Length = 302 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/232 (28%), Positives = 108/232 (46%), Gaps = 17/232 (7%) Query: 21 LMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVAKEHDVQNTFEELEKHLGR 76 L++ G + + +R ++ KA A + G A CDV VQNT EL K G Sbjct: 45 LLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGH 104 Query: 77 VNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ-QQGGSIVNVGS 135 N ++N A N R + L G+ + +I+ Q+G + +++ + Sbjct: 105 PNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITT 164 Query: 136 IVGLKGNSGQSVYSAS-KGGLVGFSRALAKEVARKKIRVNVVAPGFVHT-------DMTK 187 I G SG V SAS K G+ S++LA E + +R NV+ PG + T D T Sbjct: 165 IYAETG-SGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTG 223 Query: 188 DLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLIL 237 ++E + + IP GR G E+A+ FL + +I G V+ DGG ++++ Sbjct: 224 TFEKEMIGR-IPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLI 274 >1CYD-A nrPDB Length = 244 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 13/234 (5%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 V G +GIGR + + G ++ + R + A + G + C + D Sbjct: 12 VTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG--IEPVCVDLGDWDAT-- 67 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQ- 125 E+ +G V+ LVN A + + E NL + R MI + Sbjct: 68 -EKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRG 126 Query: 126 QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM 185 GSIVNV S+V YS++KG + ++A+A E+ KIRVN V P V TDM Sbjct: 127 VPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTDM 186 Query: 186 TKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 K + + LK+ PL +F E +V ++++FLL S +G ++VD G Sbjct: 187 GKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAG 240 >4DRY-A nrPDB Length = 281 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 65/227 (28%), Positives = 102/227 (44%), Gaps = 22/227 (9%) Query: 18 VAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH----LAFSCDVAKEHDVQNTFEELEKH 73 +AQ ++ +GY + + R + AAAG++GG A CDV V F + Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAE 108 Query: 74 LGRVNFLVNAAGINRDGLLVRTKT-EDMVSQLHTNLLGSMLTCKAAMRTMIQQ--QGGSI 130 R++ LVN AG N + + T E + NL G+ L + A R M Q +GG I Sbjct: 109 FARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTPRGGRI 168 Query: 131 VNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLK 190 +N GSI + Y+A+K + G +++ A + I + G TDMT + Sbjct: 169 INNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATDMTARMS 228 Query: 191 EEHLKKNIPLGRFGE-----TIEVAH---AVVFLLESPYITGHVLVV 229 L+ N GE TI + H AVV++ P ++ +VL + Sbjct: 229 TGVLQAN------GEVAAEPTIPIEHIAEAVVYMASLP-LSANVLTM 268 >4GKB-A nrPDB Length = 258 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 56/172 (32%), Positives = 81/172 (47%), Gaps = 16/172 (9%) Query: 74 LGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNV 133 GR++ LVN AG+N DG+ + + V+ L NL+ + ++ G+IVN+ Sbjct: 81 FGRLDGLVNNAGVN-DGIGLDAGRDAFVASLERNLIHYYAMAHYCV-PHLKATRGAIVNI 138 Query: 134 GSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDL---- 189 S + G S Y ASKG + +R A + +RVN V P V T + ++ Sbjct: 139 SSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATF 198 Query: 190 -----KEEHLKKNIPLG-RFGETIEVAHAVVFLLESP---YITGHVLVVDGG 232 K + +PLG RF E+A VFLL SP + TG L VDGG Sbjct: 199 EDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLL-SPRASHTTGEWLFVDGG 249 >3GDF-A nrPDB Length = 267 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 109/245 (44%), Gaps = 15/245 (6%) Query: 3 KVCAVFG--GSRGIGRAVAQLMARKGYRLAVI-ARNLEGAKAAAGDL----GGDHLAFSC 55 KV V G G +G+G A+ A G +A+ A +GA+ +L G A+ C Sbjct: 21 KVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYKC 80 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 V + +++ G+++ + AG D ++ E + +L G+ Sbjct: 81 QVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNGTFHCA 140 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGN--SGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 KA ++ GS+V S+ G N Q+ Y+ +K G + +R+LA E R RV Sbjct: 141 KAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW-RDFARV 199 Query: 174 NVVAPGFVHT---DMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLV 228 N ++PG++ T D ++ IP+GR G E+ A V+ S Y TG L+ Sbjct: 200 NSISPGYIDTGLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYFASDASTYTTGADLL 259 Query: 229 VDGGL 233 +DGG Sbjct: 260 IDGGY 264 >3W8F-A nrPDB Length = 260 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 65/253 (25%), Positives = 109/253 (43%), Gaps = 22/253 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV----IARNLEGAKAA-AGDLGGDHLAFSCDV 57 K V G + GIG A+A +A+ G + + ++E ++ G + D+ Sbjct: 5 KKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADL 64 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + ++ + + LG ++ LVN AGI + + + + NL A Sbjct: 65 SDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAA 124 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A+ M +Q G I+N+ S GL + +S Y A+K G+VG ++ A E A K I N + Sbjct: 125 ALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCNAIC 184 Query: 178 PGFVHTDMTKDLKE---------------EHLKKNIPLGRFGETIEVAHAVVFLLESP-- 220 PG+V T + + E E L + P +F ++ A VFL + Sbjct: 185 PGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSAAAD 244 Query: 221 YITGHVLVVDGGL 233 +TG L +DGG Sbjct: 245 QMTGTTLSLDGGW 257 >4ZJU-A nrPDB Length = 275 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 17/238 (7%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG---GDHLAFSCDVAKEHDVQNTFEEL 70 I +AQ + R+G LA N E K + G L F CDVA + ++ N F EL Sbjct: 30 IAYGIAQALHREGAELAFTYPN-EKLKKRVDEFAEQFGSKLVFPCDVAVDAEIDNAFAEL 88 Query: 71 EKHLGRVNFLVNAAGI----NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 KH V+ +V++ G DG D H S + A + ++Q + Sbjct: 89 AKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISAYSFVAMARAAKPLLQAR 148 Query: 127 GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 G ++ + + +V +K L R LA + IRVN ++ G + T Sbjct: 149 QGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVDGIRVNAISAGPIRTLAA 208 Query: 187 KDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLESPY---ITGHVLVVDGGLQLI 236 +K + +K PL R EV +A +FL SP+ ITG +L VD G + Sbjct: 209 SGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLC-SPWASGITGEILYVDAGFNTV 265 >1P33-A nrPDB Length = 289 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/188 (31%), Positives = 89/188 (47%), Gaps = 26/188 (13%) Query: 73 HLGRVNFLVNAAGINRDGLLVRTKT-------------EDMVSQLH-TNLLGSMLTCKA- 117 H GR + LVN A L+R E + L +N + KA Sbjct: 100 HWGRCDVLVNNASSFYPTPLLRKDAGEGGSSVGDKESLEVAAADLFGSNAIAPYFLIKAF 159 Query: 118 AMR---TMIQQQGGS--IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 172 A R T +Q+G S IVN+ + + G ++Y+ +K L G +R+ A E+A +IR Sbjct: 160 AQRVADTRAEQRGTSYSIVNMVDAMTSQPLLGYTMYTMAKEALEGLTRSAALELASLQIR 219 Query: 173 VNVVAPGF--VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YITGHVL 227 VN V+PG + DM ++E++ +K +PL + + E VV L SP YITG + Sbjct: 220 VNGVSPGLSVLPDDMPFSVQEDYRRK-VPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCI 278 Query: 228 VVDGGLQL 235 VDGG L Sbjct: 279 KVDGGYSL 286 >3E9N-A nrPDB Length = 245 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 59/220 (26%), Positives = 108/220 (49%), Gaps = 12/220 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K+ V G + G+G + + ++R + + + RN E A A G + D+ KE Sbjct: 6 KIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEGVE--PIESDIVKEVL 62 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + ++L K+L V+ LV+AA + RD T V++ H +L +++ R + Sbjct: 63 EEGGVDKL-KNLDHVDTLVHAAAVARD----TTIEAGSVAEWHAHLDLNVIVPAELSRQL 117 Query: 123 I---QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + + G ++ + S G + G ++Y+ASK L G + A KE A IRV+ V+PG Sbjct: 118 LPALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPG 177 Query: 180 FVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLES 219 +T M + L + N + E E+A+A+ F++++ Sbjct: 178 PTNTPMLQGLMDSQ-GTNFRPEIYIEPKEIANAIRFVIDA 216 >2BFA-A nrPDB Length = 288 Score = 60.8 bits (146), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 62/191 (32%), Positives = 87/191 (45%), Gaps = 32/191 (16%) Query: 73 HLGRVNFLVNAAGINRDGLLVR-----------------TKTEDMVSQLHTNLLGSMLTC 115 H GR + LVN A L+R T T D+ +N + Sbjct: 99 HWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADL---FGSNAIAPYFLI 155 Query: 116 KA-AMR---TMIQQQGG--SIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK 169 KA A R T + +G SI+N+ + + G ++Y+ +KG L G +R+ A E+A Sbjct: 156 KAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPL 215 Query: 170 KIRVNVVAPGF--VHTDMTKDLKEEHLKKNIPL-GRFGETIEVAHAVVFLLES--PYITG 224 +IRVN V PG + DM + E H K +PL R EV+ V+FL S YITG Sbjct: 216 QIRVNGVGPGLSVLVDDMPPAVWEGHRSK-VPLYQRDSSAAEVSDVVIFLCSSKAKYITG 274 Query: 225 HVLVVDGGLQL 235 + VDGG L Sbjct: 275 TCVKVDGGYSL 285 >4NR0-A nrPDB Length = 273 Score = 60.5 bits (145), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 63/236 (26%), Positives = 98/236 (41%), Gaps = 15/236 (6%) Query: 14 IGRAVAQLMARKGYRLAVIARN--LEG--AKAAAGDLGGDHLAFSCDVAKEHDVQNTFEE 69 I +A M R+G LA +N L G + A+G L F CDVA + ++ F Sbjct: 20 IASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCFPCDVADDSQIEAVFAA 79 Query: 70 LEKHLGRVNFLVN----AAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQ 125 L KH ++ +V+ A G DG T + H S + A R M++ Sbjct: 80 LGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISAYSFIALAKAGREMMKG 139 Query: 126 QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM 185 + GS++ + + + +V +K L R LA + + RVN V+ G + T Sbjct: 140 RNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGAEGTRVNAVSAGPIRTLA 199 Query: 186 TKDLKEEHL-----KKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 +K ++ PL R EV +A FL + I+G +L VDGG Sbjct: 200 ASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLASGISGEILYVDGGFN 255 >2QHX-A nrPDB Length = 328 Score = 60.5 bits (145), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 62/191 (32%), Positives = 87/191 (45%), Gaps = 32/191 (16%) Query: 73 HLGRVNFLVNAAGINRDGLLVR-----------------TKTEDMVSQLHTNLLGSMLTC 115 H GR + LVN A L+R T T D+ +N + Sbjct: 139 HWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFG---SNAIAPYFLI 195 Query: 116 KA-AMR---TMIQQQGG--SIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK 169 KA A R T + +G SI+N+ + + G ++Y+ +KG L G +R+ A E+A Sbjct: 196 KAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPL 255 Query: 170 KIRVNVVAPGF--VHTDMTKDLKEEHLKKNIPL-GRFGETIEVAHAVVFLLES--PYITG 224 +IRVN V PG + DM + E H K +PL R EV+ V+FL S YITG Sbjct: 256 QIRVNGVGPGLSVLVDDMPPAVWEGHRSK-VPLYQRDSSAAEVSDVVIFLCSSKAKYITG 314 Query: 225 HVLVVDGGLQL 235 + VDGG L Sbjct: 315 TCVKVDGGYSL 325 >2NWQ-A nrPDB Length = 272 Score = 60.5 bits (145), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 47/190 (24%), Positives = 83/190 (43%), Gaps = 4/190 (2%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH--LAFSCDVA 58 M + G + G G A A+ A G+ L + R E +A AG+L L + DV Sbjct: 20 MSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVR 79 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRT-KTEDMVSQLHTNLLGSMLTCKA 117 + + L + + L+N AG+ ++ +D + + TN+ G + + + Sbjct: 80 DRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRL 139 Query: 118 AMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 + +I G SIVN+GS+ G G VY +K + FS L ++ +RV + Sbjct: 140 LLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNL 199 Query: 177 APGFVHTDMT 186 PG ++ + Sbjct: 200 EPGLCESEFS 209 >4RGB-A nrPDB Length = 294 Score = 60.5 bits (145), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 68/268 (25%), Positives = 114/268 (42%), Gaps = 36/268 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKG----------------YRLAVIARNLEGAKAAAGDL 46 +V + G +RG GR+ A + A +G Y+L LE Sbjct: 26 RVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTY-EELEETARLVEKT 84 Query: 47 GGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHT 106 G + L DV + +Q F+ + G ++ ++ AG+ R +E + L Sbjct: 85 GQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGLDI 144 Query: 107 NLLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGL----KGNSGQSVYSASKGGLVGFSRA 161 L+G T + A+ M ++ QGG+++ S++ L G G Y SK + G R+ Sbjct: 145 MLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLVRS 204 Query: 162 LAKEVARKKIRVNVVAPGFVHTDMTKD------LKEEH------LKKNIPLGRFGETIEV 209 A +A +IRVN VAP T M + + EE+ + +P E +V Sbjct: 205 YALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEPRDV 264 Query: 210 AHAVVFLLESP--YITGHVLVVDGGLQL 235 ++A++FL+ TG VL VD G+ + Sbjct: 265 SNAILFLISDAGRSFTGSVLKVDAGMDV 292 >5KOI-A nrPDB Length = 293 Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 52/200 (26%), Positives = 92/200 (46%), Gaps = 12/200 (6%) Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-- 105 G CDV V FEE+EK G ++FLV+A G + D ++ + D+ ++ + Sbjct: 78 GSDFVLPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFS-DKTELKGRYADVTTRENFS 136 Query: 106 -TNLLGSMLTCKAAMRT-MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALA 163 T ++ + + A R + + GGSI+ + + +V +K L R LA Sbjct: 137 RTMVISAYSFTEVAQRAEKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLA 196 Query: 164 KEVARKKIRVNVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE 218 + + IRVN ++ G V T + + + ++N PL R + +V + V+LL Sbjct: 197 ADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLS 256 Query: 219 --SPYITGHVLVVDGGLQLI 236 S +TG + VD G ++ Sbjct: 257 DLSSGVTGEIHFVDSGYNIV 276 >2DKN-A nrPDB Length = 255 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 71/269 (26%), Positives = 113/269 (42%), Gaps = 54/269 (20%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 V A+ G + GIG A+ +L+AR G+ + I R +A GG A + Sbjct: 2 SVIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGRETAVAA------- 54 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 L++ G ++ LV AG+ V +V + N G + Sbjct: 55 ------VLDRCGGVLDGLVCCAGVG-----VTAANSGLV--VAVNYFGVSALLDGLAEAL 101 Query: 123 IQQQGGSIVNVGSIVG--------------LKGNSGQSV------------YSASKGGLV 156 + Q + V VGSI L G+ +++ Y+ SK + Sbjct: 102 SRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVT 161 Query: 157 GFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKE-----EHLKKNI-PLGRFGETIEVA 210 +R + A + +R+NVVAPG V T + + K E ++ + PLGR E EVA Sbjct: 162 CLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEPREVA 221 Query: 211 HAVVFLL--ESPYITGHVLVVDGGLQLIL 237 A+ FLL ++ +I G VL VDGG+ ++ Sbjct: 222 EAIAFLLGPQASFIHGSVLFVDGGMDALM 250 >4M89-A nrPDB Length = 261 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 61/240 (25%), Positives = 104/240 (43%), Gaps = 19/240 (7%) Query: 12 RGIGRAVAQLMARKGYRLA---VIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFE 68 R I +A+ +G LA V+ + E + A +L + L F CDVA + ++ F Sbjct: 18 RSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSE-LVFRCDVASDDEINQVFA 76 Query: 69 ELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 +L KH ++ LV++ G G + + + + + H S+ A R M++ Sbjct: 77 DLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAYSLPALAKAARPMMR 136 Query: 125 QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT- 183 + +IV + + ++ +V +K L R A + ++ IR N ++ G + T Sbjct: 137 GRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEGIRCNGISAGPIKTL 196 Query: 184 ------DMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 D K L H+ + PL R EV + FLL S ITG + VDGG + Sbjct: 197 AASGIADFGKLLG--HVAAHNPLRRNVTIEEVGNTAAFLLSDLSSGITGEITYVDGGYSI 254 >3GRK-A nrPDB Length = 293 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 55/200 (27%), Positives = 83/200 (41%), Gaps = 13/200 (6%) Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN 107 G +A CDVA + FE LEK G+++FLV+A G + L + + Sbjct: 81 GAFVAGHCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNT 140 Query: 108 LLGSMLTCKAAMR--TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 +L S+ + A R + GGSI+ + K +V +K L + LA + Sbjct: 141 MLISVYSLTAVSRRAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVD 200 Query: 166 VARKKIRVNVVAPGFVHT-------DMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE 218 + + IRVN ++ G + T D LK N PL R EV ++ L Sbjct: 201 LGPQNIRVNAISAGPIKTLAASGIGDFRYILKWNEY--NAPLRRTVTIDEVGDVGLYFLS 258 Query: 219 --SPYITGHVLVVDGGLQLI 236 S +TG V D G +I Sbjct: 259 DLSRSVTGEVHHADSGYHVI 278 >3PXX-A nrPDB Length = 287 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 74/282 (26%), Positives = 111/282 (39%), Gaps = 54/282 (19%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKG----------------YRLAVIARNLEGAKAAAGD 45 DKV V GG+RG GR+ A +A +G Y LA +R+LE A Sbjct: 10 DKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLAT-SRDLEEAGLEVEK 68 Query: 46 LGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH 105 G DV V G+++ +V AGI G + Sbjct: 69 TGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLG--AHLPVQAFADAFD 126 Query: 106 TNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL-----------KGNSGQSVYSASKGG 154 + +G + T AA+ + G SI+ GS+ GL G + YS +K Sbjct: 127 VDFVGVINTVHAALPYLTS--GASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQL 184 Query: 155 LVGFSRALAKEVARKKIRVNVVAPGFVHTDM----------TKDLKEEH---------LK 195 + ++ LA ++A + IR NV+ P V+TDM DL+ Sbjct: 185 VDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFPAM 244 Query: 196 KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 + +P + E ++++AV FL ES Y+TG VD G L Sbjct: 245 QAMPTP-YVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >3K2E-A nrPDB Length = 296 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 13/200 (6%) Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQ 103 G L CDV+ V N F+ L + G ++F+V+A + G V T + ++ Sbjct: 80 GVKLTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTS 139 Query: 104 LHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALA 163 +H + T A+ + GGSI+ + K +V K L + LA Sbjct: 140 MHISCYS--FTYIASKAEPLMTNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLA 197 Query: 164 KEVARKKIRVNVVAPGFVHTDMTKDLKEEHL-----KKNIPLGRFGETIEVAHAVVFLLE 218 ++ +++IRVN ++ G V T + + + H K N PL R +V A ++LL Sbjct: 198 VDLGKQQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLS 257 Query: 219 S--PYITGHVLVVDGGLQLI 236 TG + VD G ++ Sbjct: 258 DLGRGTTGETVHVDCGYHVV 277 >5TF4-A nrPDB Length = 274 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 53/195 (27%), Positives = 83/195 (42%), Gaps = 17/195 (8%) Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLG 110 CDV+ + F +EK G+++FLV+A G + G V + + ++ ++ Sbjct: 69 CDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYS 128 Query: 111 SMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK 170 K A + M GGSI+ + K +V +K L + LA ++ K Sbjct: 129 LTALTKRAEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKH 186 Query: 171 IRVNVVAPGFVHT-------DMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPY 221 IRVN ++ G + T D LK N PL R EV + ++LL S Sbjct: 187 IRVNAISAGPIKTLAASGIGDFRYILKWNEY--NAPLRRTVTIEEVGDSALYLLSDLSRS 244 Query: 222 ITGHVLVVDGGLQLI 236 +TG V VD G +I Sbjct: 245 VTGEVHHVDSGYNII 259 >3OIG-A nrPDB Length = 266 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 57/249 (22%), Positives = 99/249 (39%), Gaps = 37/249 (14%) Query: 12 RGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG-----DHLAFSCDVAKEHDVQNT 66 R I +A+ + G RL + E + + +L G D + CDV + +++ Sbjct: 19 RSIAWGIARSLHEAGARL-IFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETC 77 Query: 67 FEELEKHLGRVNFLVNAAGI-------------NRDGLLVRTKTEDMVSQLHTNLLGSML 113 F +++ +G ++ + + NRDG L L N+ L Sbjct: 78 FASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFL-----------LAHNISSYSL 126 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 T + +GGSIV + + G +V +K L + LA ++ ++ IRV Sbjct: 127 TAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRV 186 Query: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G + T K + + + +++ PL R EV FL S ITG Sbjct: 187 NSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGEN 246 Query: 227 LVVDGGLQL 235 L VD G + Sbjct: 247 LHVDSGFHI 255 >1A27-A nrPDB Length = 289 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 53/190 (27%), Positives = 86/190 (45%), Gaps = 13/190 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNL-------EGAKAAAGDLGGDHLAF 53 V + G S GIG +A +A + +++ R+L E A+A A G Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE-TL 62 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 DV V E + + GRV+ LV AG+ G L + + S L N++G++ Sbjct: 63 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 120 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +A + M ++ G ++ GS+ GL G VY ASK L G +LA + + + Sbjct: 121 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 174 NVVAPGFVHT 183 +++ G VHT Sbjct: 181 SLIECGPVHT 190 >6CGE-A nrPDB Length = 328 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 53/190 (27%), Positives = 86/190 (45%), Gaps = 13/190 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNL-------EGAKAAAGDLGGDHLAF 53 V + G S GIG +A +A + +++ R+L E A+A A G Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE-TL 63 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 DV V E + + GRV+ LV AG+ G L + + S L N++G++ Sbjct: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +A + M ++ G ++ GS+ GL G VY ASK L G +LA + + + Sbjct: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 Query: 174 NVVAPGFVHT 183 +++ G VHT Sbjct: 182 SLIECGPVHT 191 >3U9L-A nrPDB Length = 324 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 54/229 (23%), Positives = 96/229 (41%), Gaps = 17/229 (7%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLA-----VIARNLEGAKAAAG---DLGGDHLAFS 54 K+ + G S G GR A+ +A G+R+ ++ RN +A AG D D Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLE 65 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 DV + V +++ GR++ L++ AG G E N+L + Sbjct: 66 LDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVLSTQRV 125 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ-SVYSASKGGLVGFSRALAKEVARKKIRV 173 +AA+ M +Q+ G ++ + S G + Y A+K + + A+E++R I Sbjct: 126 NRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRWGIET 185 Query: 174 NVVAPG--------FVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVV 214 +++ PG F H+ + D + + P GE I+ A A + Sbjct: 186 SIIVPGAFTSGTNHFAHSGVPDDHARQAEYEAGPNAGLGEEIKKAFAAI 234 >5PGZ-A nrPDB Length = 276 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 29/189 (15%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG---DLGGDHLAFSCDVAK 59 K V G S+GIGR +A +++ G + + AR+ EG + +LG A Sbjct: 19 KKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGA---------AS 69 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGI--NRDGLLVRTKTEDMVSQLH-----------T 106 H + T E++ F+V A + D L++ T+ +S H Sbjct: 70 AHYIAGTMEDMT---FAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEV 126 Query: 107 NLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 N L ++ AA+ M++Q GSI + S+ G + YSASK L GF + E+ Sbjct: 127 NFLSYVVMSTAAL-PMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 Query: 167 ARKKIRVNV 175 K+ V++ Sbjct: 186 YITKVNVSI 194 >1OAA-A nrPDB Length = 259 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 57/206 (27%), Positives = 86/206 (41%), Gaps = 21/206 (10%) Query: 4 VCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNLEGAKAAAGDLGGDHLAF-----SC 55 VC + G SRG GRA+A +AR G + V AR+ + +LG + Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 56 DVAKEHDVQ---NTFEELEKH--LGRVNFLVNAAGIN--RDGLLVRTKTEDMVSQLHTNL 108 D+ E VQ + EL + L R+ + NAA + G L ++ + N Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALN- 126 Query: 109 LGSMLTCKAAMRTMIQQQGG---SIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 L SML + Q G ++VN+ S+ L+ G +Y A K + LA E Sbjct: 127 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 166 VARKKIRVNVVAPGFVHTDMTKDLKE 191 +RV APG + DM + +E Sbjct: 187 --EPSVRVLSYAPGPLDNDMQQLARE 210 >1FJH-A nrPDB Length = 257 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 10/103 (9%) Query: 144 GQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKD-LKEEHLKKNI---- 198 G Y+ SK L R A +R+N +APG T + + L++ ++I Sbjct: 151 GNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFV 210 Query: 199 -PLGRFGETIEVAHAVVFLLESP---YITGHVLVVDGGLQLIL 237 P+GR E E+A + FL+ SP Y+ G +V+DGG+ ++ Sbjct: 211 PPMGRRAEPSEMASVIAFLM-SPAASYVHGAQIVIDGGIDAVM 252 >1SNY-A nrPDB Length = 267 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 51/206 (24%), Positives = 95/206 (46%), Gaps = 32/206 (15%) Query: 7 VFGGSRGIGRAVAQLM---ARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 + G +RG+G + + + + L RN E AK DL +H E D+ Sbjct: 26 ITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELE-DLAKNHSNIHI---LEIDL 81 Query: 64 QNTFEELEKHLGRV---------NFLVNAAGI-NRDGLLVRTKTEDMVSQLHTNLLGSML 113 +N F+ +K + + N L N AGI + + ++++++ L TN + ++ Sbjct: 82 RN-FDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIM 140 Query: 114 TCKAAMRTM--------IQQQG---GSIVNVGSIVG-LKGNS--GQSVYSASKGGLVGFS 159 KA + + Q G +I+N+ SI+G ++GN+ G Y SK L + Sbjct: 141 LAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAAT 200 Query: 160 RALAKEVARKKIRVNVVAPGFVHTDM 185 ++L+ ++ ++I + PG+V TDM Sbjct: 201 KSLSVDLYPQRIMCVSLHPGWVKTDM 226 >1MG5-A nrPDB Length = 255 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/183 (25%), Positives = 75/183 (40%), Gaps = 20/183 (10%) Query: 13 GIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEK 72 GIG ++ + ++ + VI +E AA +L + + +DV E K Sbjct: 17 GIGLDTSKELLKRDLKNLVILDRIENP-AAIAELKAINPKVTVTF-YPYDVTVPIAETTK 74 Query: 73 -------HLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQ 125 L V+ L+N AGI D + RT + N G + T A + ++ Sbjct: 75 LLKTIFAQLKTVDVLINGAGILDDHQIERT--------IAVNYTGLVNTTTAILDFWDKR 126 Query: 126 QGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 +GG I N+GS+ G VYS +K +V F+ +LAK + V PG Sbjct: 127 KGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITR 186 Query: 183 TDM 185 T + Sbjct: 187 TTL 189 >1B15-A nrPDB Length = 254 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 11/122 (9%) Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 +++ L V+ L+N AGI D + RT + N G + T A + +++ Sbjct: 75 LKKIFDQLKTVDILINGAGILDDHQIERT--------IAINFTGLVNTTTAILDFWDKRK 126 Query: 127 GGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 GG I N+ S+ G VYSASK +V F+ +LAK + + PG T Sbjct: 127 GGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGVTAYSINPGITRT 186 Query: 184 DM 185 + Sbjct: 187 PL 188 >2HRB-A nrPDB Length = 274 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 58/235 (24%), Positives = 91/235 (38%), Gaps = 57/235 (24%) Query: 3 KVCAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHLA---FSCDVA 58 +V V G +RGIG A+A+ + R+ + + AR++ +AA L + L+ D+ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 62 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGI---NRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 ++ + L K G +N LVN A + + D + K E L TN + C Sbjct: 63 DLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAE---MTLKTNFFATRNMC 119 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKG--NSGQ---------------------------- 145 + M + G +VN+ S+ L+ N + Sbjct: 120 NELLPIM--KPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTK 177 Query: 146 -----------SVYSASKGGLVGFSRALAKEVARK----KIRVNVVAPGFVHTDM 185 S Y SK G+ SR LA+ + K +I VN PG V TDM Sbjct: 178 NEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDM 232 >4ALL-A nrPDB Length = 277 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 14/198 (7%) Query: 50 HLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNA-AGINRDGLLVR-TKTEDMVSQLHTN 107 HL + DV + +V N FE++ K +G ++ + ++ A N + L R ++T L + Sbjct: 82 HL-YQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQD 140 Query: 108 LLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVA 167 + LT A + +GGSIV + G +V +K L + LA ++ Sbjct: 141 ISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLG 200 Query: 168 RKKIRVNVVAPGFVHTDMTKD-------LKEEHLKKNIPLGRFGETIEVAHAVVFLLE-- 218 IRVN ++ G + T K LKE +++ PL R + +EV +LL Sbjct: 201 PDNIRVNAISAGPIRTLSAKGVGGFNTILKE--IEERAPLKRNVDQVEVGKTAAYLLSDL 258 Query: 219 SPYITGHVLVVDGGLQLI 236 S +TG + VD G I Sbjct: 259 SSGVTGENIHVDSGFHAI 276 >3KZV-A nrPDB Length = 254 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 83/193 (43%), Gaps = 4/193 (2%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAV--IARNLEGAKAAAGDLGGDHLAFSCDVA 58 M KV V G SRGIG+++ ++ V +AR+ K G D+ Sbjct: 1 MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDIT 60 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 ++ ++ K G+++ LV AG+ V + +L+ S+++ Sbjct: 61 EDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGI 120 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 +++ G++V V S S Y +SK L F+ LA E ++++ VAP Sbjct: 121 ALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAP 178 Query: 179 GFVHTDMTKDLKE 191 G V TDM +++E Sbjct: 179 GIVDTDMQVNIRE 191 >4Z3K-A nrPDB Length = 275 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 19/212 (8%) Query: 4 VCAVFGGSRGIGRA---VAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH-----LAFSC 55 VC + G SRG GR + + G L + ARN E + +LG + + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 56 DVAKEHDVQN---TFEELEKHLGRVN-FLVNAAGINRD---GLLVRTKTEDMVSQLHTNL 108 D+ E +Q EL + G L+N AG D G + + + + + NL Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 142 Query: 109 LGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 + + ++ G ++VN+ S+ L+ G ++Y A K + LA E Sbjct: 143 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 201 Query: 167 ARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNI 198 +RV APG + TDM + +E + ++ Sbjct: 202 -EPNVRVLNYAPGPLDTDMQQLARETSVDPDM 232 >3DWF-A nrPDB Length = 276 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 48/174 (27%), Positives = 77/174 (44%), Gaps = 7/174 (4%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK---AAAGDLGGDHLAFSCDVAKEHDV 63 V G S+GIGR +A +A+ G + V AR+ E + A +LG + ++ Sbjct: 16 VTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDMTF 75 Query: 64 QNTF-EELEKHLGRVNFLV-NAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 F E +G ++ L+ N NR + +++ + N ++ AAM Sbjct: 76 AEEFVAEAGNLMGGLDMLILNHVLYNRLTFF-HGEIDNVRKSMEVNFHSFVVLSVAAMPM 134 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 ++Q Q GSI V S+ G + YSASK L GF L E K+ V++ Sbjct: 135 LMQSQ-GSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSI 187 >4HWK-A nrPDB Length = 288 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 19/212 (8%) Query: 4 VCAVFGGSRGIGRA---VAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH-----LAFSC 55 VC + G SRG GR + + G L + ARN E + +LG + + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 56 DVAKEHDVQN---TFEELEKHLGRVN-FLVNAAGINRD---GLLVRTKTEDMVSQLHTNL 108 D+ E +Q EL + G L+N AG D G + + + + + NL Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 155 Query: 109 LGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 + + ++ G ++VN+ S+ L+ G ++Y A K + LA E Sbjct: 156 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 214 Query: 167 ARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNI 198 +RV APG + TDM + +E + ++ Sbjct: 215 -EPNVRVLNYAPGPLDTDMQQLARETSVDPDM 245 >5I9N-A nrPDB Length = 276 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 56/241 (23%), Positives = 97/241 (40%), Gaps = 16/241 (6%) Query: 11 SRGIGRAVAQLMARKGYRLAVIA---RNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67 +R I +A+ R+G LA R + A + G + L F CDVA + + F Sbjct: 17 NRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE-LVFPCDVADDAQIDALF 75 Query: 68 EELEKHLGRVNFLVNAAGI-NRD---GLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 L+ H ++ LV++ G R+ G + T + H S A M+ Sbjct: 76 ASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPML 135 Query: 124 QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 S++ + + + + +K L R LA + K +RVN ++ G + T Sbjct: 136 SDD-ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPIKT 194 Query: 184 DMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 +K + ++ N PL R +V +A FLL + +T V+ VD G + Sbjct: 195 LAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAV 254 Query: 237 L 237 + Sbjct: 255 V 255 >2PD3-A nrPDB Length = 275 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 58/240 (24%), Positives = 107/240 (44%), Gaps = 17/240 (7%) Query: 11 SRGIGRAVAQLMARKGYRLAVIARN--LEG-AKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67 ++ I +AQ +G LA N LE + A +L ++ + DV+KE ++ + Sbjct: 17 NKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYV-YELDVSKEEHFKSLY 75 Query: 68 EELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM--IQQ 125 ++K LG ++F+V++ L + E S +T + S+ + T+ + Sbjct: 76 NSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSLIELTNTLKPLLN 135 Query: 126 QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT-- 183 G S++ + + K + +V +K L R LA ++ + IRVN ++ G + T Sbjct: 136 NGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIRVNALSAGPIRTLA 195 Query: 184 -----DMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPY--ITGHVLVVDGGLQLI 236 D LK + N PL + EV +A ++LL S ++G V VD G ++ Sbjct: 196 SSGIADFRMILKWNEI--NAPLRKNVSLEEVGNAGMYLLSSLSSGVSGEVHFVDAGYHVM 253 >3BHI-A nrPDB Length = 276 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 59/234 (25%), Positives = 93/234 (39%), Gaps = 57/234 (24%) Query: 4 VCAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHLA---FSCDVAK 59 V V GG++GIG A+ + + R + + AR++ +AA L + L+ D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVS---QLHTNLLGSMLTCK 116 ++ + L K G ++ LVN AGI V T + + TN G+ C Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGI---AFKVADPTPFHIQAEVTMKTNFFGTRDVCT 122 Query: 117 AAMRTMIQQQGGSIVNVGSI---------------------------VGL---------- 139 + +I+ Q G +VNV SI VGL Sbjct: 123 ELL-PLIKPQ-GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKK 180 Query: 140 ----KGNSGQSVYSASKGGLVGFSRALAKEVARK----KIRVNVVAPGFVHTDM 185 K S Y +K G+ SR A++++ + KI +N PG+V TDM Sbjct: 181 GVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDM 234 >1N5D-A nrPDB Length = 288 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 57/235 (24%) Query: 3 KVCAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHLA---FSCDVA 58 +V V G ++GIG A+ + + R+ + + AR++ +AA L + L+ D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVS---QLHTNLLGSMLTC 115 ++ + L K G ++ LVN A I + T + + TN +G+ C Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAI---AFQLDNPTPFHIQAELTMKTNFMGTRNVC 121 Query: 116 KAAMRTMIQQQGGSIVNVGS---------------------------IVGL--------- 139 + +I+ QG +VNV S +VGL Sbjct: 122 TELL-PLIKPQG-RVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTK 179 Query: 140 -----KGNSGQSVYSASKGGLVGFSRALAKEV----ARKKIRVNVVAPGFVHTDM 185 K S Y +K G+ SR A+++ A KI +N PG+V TDM Sbjct: 180 NGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDM 234 >5TQV-A nrPDB Length = 233 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 9/186 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G SRG+GR + R G+ + AR+ + + AA LG A + D+ + Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARD-DASLAALRALGAH--AHALDITQPEQ 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + +L+ V +V+ R + ++D + +HTN+ G M + + Sbjct: 67 IAALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLV 126 Query: 123 IQQQGGSIV---NVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 +G V +GSI G +G +Y ASK L R +A R ++ + PG Sbjct: 127 EDARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLR-IASLQTRHAACIS-LHPG 183 Query: 180 FVHTDM 185 +V TDM Sbjct: 184 WVRTDM 189 >5L51-A nrPDB Length = 324 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/270 (21%), Positives = 94/270 (34%), Gaps = 89/270 (32%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARN----LEGAKAAAGDLG---GDHL-AFS 54 + V G ++GIG + + +A KG + + +R+ +E + +LG GD++ + Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGIN--------------------------- 87 DVA V + ++ G ++ LVN AG+N Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSGAA 135 Query: 88 --------RDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVG- 138 G LV T E + TN GS +A + + Q IVNV S + Sbjct: 136 KTEPYHPKATGRLVET-VEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLSS 194 Query: 139 -----------------------------------LKGNSGQ-------SVYSASKGGLV 156 + G + S Y SK L Sbjct: 195 LVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAALN 254 Query: 157 GFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 ++R +AK+ R+N V PG+ TD++ Sbjct: 255 AYTRIIAKKYP--SFRINAVCPGYTKTDLS 282 >5WQO-A nrPDB Length = 234 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 45/191 (23%), Positives = 81/191 (42%), Gaps = 14/191 (7%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKA--AAGDLGGDHLAFSCDVAKEHDVQ 64 + G SRGIG +A ++G ++ +AR +G+ A + G+ L +HD Sbjct: 11 IVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHDCA 70 Query: 65 NTFEELEKHLG--RVNFLVNAAGI--NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 E + + LG R++ L+ AGI + + E TN + + +A Sbjct: 71 ---ERIGEMLGERRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARALSG 127 Query: 121 TMIQQQGGSIVNVGS---IVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + +GG + + S + L ++ +Y ASK L R+ E + ++ Sbjct: 128 RV--SRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLLH 185 Query: 178 PGFVHTDMTKD 188 PG+V T+M D Sbjct: 186 PGWVRTEMGGD 196 >2PTG-A nrPDB Length = 319 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 17/127 (13%) Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSV-YSASKGGLVGFSRALAKEVARKK-IRVNVVAPGF 180 + ++GGS + + I K G S++K L R LA E R + +RVN ++ G Sbjct: 180 LMKEGGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGP 239 Query: 181 VHTDMTK-----------DLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPY---ITGHV 226 + + DL ++ + N PL + E+ +V A +FLL SP +TG Sbjct: 240 LKSRAASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLL-SPLARAVTGAT 298 Query: 227 LVVDGGL 233 L VD GL Sbjct: 299 LYVDNGL 305 >2NTV-A nrPDB Length = 268 Score = 36.2 bits (82), Expect = 0.013, Method: Compositional matrix adjust. Identities = 38/153 (24%), Positives = 60/153 (39%), Gaps = 21/153 (13%) Query: 98 EDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVG 157 ED+ +H + KA + +I GGSIV + + + + +K L Sbjct: 113 EDVSKGIHISTYSYASLAKALL--LIMNSGGSIVGM-DFDPTRAMPAYNWMTVAKSALES 169 Query: 158 FSRALAKEVARKKIRVNVVAPGFVHT---------------DMTKDLKEEHLKKNIPLG- 201 +R +A+E + +R N+VA G + T L EE + P+G Sbjct: 170 VNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGW 229 Query: 202 RFGETIEVAHAVVFLLES--PYITGHVLVVDGG 232 + VA V LL P TG ++ DGG Sbjct: 230 NMKDPTPVAKTVCALLSEWLPATTGSIIYADGG 262 >3O26-A nrPDB Length = 311 Score = 35.4 bits (80), Expect = 0.023, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%) Query: 146 SVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM 185 + Y+ SK L ++R LA ++ K +VN V PG V T+M Sbjct: 234 AAYTTSKACLNAYTRVLANKIP--KFQVNCVCPGLVKTEM 271 Score = 30.0 bits (66), Expect = 0.85, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%) Query: 5 CAVF-GGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG---DHLAF-SCDVAK 59 CAV GG++GIG + + ++ G + + R++ A L +++ F DV Sbjct: 14 CAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVTD 73 Query: 60 EHDVQNTFEELEK-HLGRVNFLVNAAGI 86 ++ + K H G+++ LVN AG+ Sbjct: 74 PIATMSSLADFIKTHFGKLDILVNNAGV 101 >4OYR-A nrPDB Length = 289 Score = 34.3 bits (77), Expect = 0.051, Method: Compositional matrix adjust. Identities = 50/206 (24%), Positives = 76/206 (36%), Gaps = 37/206 (17%) Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAG-----INRDGLLVRT----------KTEDMVSQL 104 E DVQN E L GRV + A ++ G + +T D+ + Sbjct: 82 ELDVQNE-EHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGI 140 Query: 105 HTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAK 164 H + KA + M GGSIV + + + + +K L +R +A+ Sbjct: 141 HISAYSYASMAKALLPIM--NPGGSIVGM-DFDPSRAMPAYNWMTVAKSALESVNRFVAR 197 Query: 165 EVARKKIRVNVVAPGFVHTDMTK---------------DLKEEHLKKNIPLG-RFGETIE 208 E + +R N+VA G + T L EE + P+G + Sbjct: 198 EAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATP 257 Query: 209 VAHAVVFLLES--PYITGHVLVVDGG 232 VA V LL P TG ++ DGG Sbjct: 258 VAKTVCALLSDWLPATTGDIIYADGG 283 >4PSH-A nrPDB Length = 227 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 10/97 (10%) Query: 136 IVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK-IRVNVVAPGFVHTDMTKD-LKEEH 193 +VGL + + G +VGF LAKE+AR+ + + +V DMT D L Sbjct: 12 LVGLSADFPPFEFVDENGNIVGFDVDLAKEIARRLGVELKIV-------DMTFDGLIPSL 64 Query: 194 LKKNIPLGRFGETIEVAHAVVFLLESPYI-TGHVLVV 229 L K I + G TI V PY G V+VV Sbjct: 65 LTKKIDVIISGMTITEERKKVVAFSDPYFDAGQVIVV 101 >4P71-A nrPDB Length = 792 Score = 30.0 bits (66), Expect = 0.85, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 142 NSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLG 201 + GQ+ +G LVG+ AL E+A+K +++ P F+ + ++ + HL K L Sbjct: 642 HPGQTARIEREGRLVGYLGALHPELAKK---LDLEQPVFLFELLLAEVVDGHLPKFRELS 698 Query: 202 RFGE 205 RF E Sbjct: 699 RFPE 702 >4V73-BP nrPDB Length = 115 Score = 30.0 bits (66), Expect = 0.85, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 23/32 (71%) Query: 183 TDMTKDLKEEHLKKNIPLGRFGETIEVAHAVV 214 +++ K L++E +K+++P R G+T+EV VV Sbjct: 2 SNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVV 33 >3F6S-A nrPDB Length = 148 Score = 30.0 bits (66), Expect = 0.95, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 16/84 (19%) Query: 1 MDKVCAVFGGSRGIGRAVAQ----LMARKGYRLAVIARNLEGAKAAAGDL--GGDHLAFS 54 M KV VFG S G ++AQ L+A G+ + + L A A+A +L G D + F Sbjct: 1 MSKVLIVFGSSTGNTESIAQKLEELIAAGGHEVTL----LNAADASAENLADGYDAVLFG 56 Query: 55 C------DVAKEHDVQNTFEELEK 72 C D+ + D + FEE ++ Sbjct: 57 CSAWGMEDLEMQDDFLSLFEEFDR 80 >3SLK-A nrPDB Length = 795 Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 85/197 (43%), Gaps = 26/197 (13%) Query: 7 VFGGSRGIGRAVAQ-LMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF-------SCDVA 58 V GG+ +G VA+ L+ +G R V+ A + A +L A+ +CDVA Sbjct: 535 VTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQACDVA 594 Query: 59 KEHDVQNTFEEL-EKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + + ++H + +V+AAG+ DG+ E + L + G+ Sbjct: 595 DRETLAKVLASIPDEH--PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGA------ 646 Query: 118 AMRTMIQ--QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 R +++ ++V S+ G+ G+ GQ Y+A+ F ALA++ + + Sbjct: 647 --RNLLELIDPDVALVLFSSVSGVLGSGGQGNYAAAN----SFLDALAQQRQSRGLPTRS 700 Query: 176 VAPG-FVHTDMTKDLKE 191 +A G + M L+E Sbjct: 701 LAWGPWAEHGMASTLRE 717 >5LCX-A nrPDB Length = 316 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 20/36 (55%), Gaps = 2/36 (5%) Query: 151 SKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMT 186 SK L +++ AK+ R+N + PG+ TD+T Sbjct: 243 SKAALNAYTKIAAKKYP--SFRINAICPGYAKTDIT 276 >4B4O-A nrPDB Length = 298 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 9/68 (13%) Query: 9 GGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA----FSCDVAKEHDVQ 64 GG+ IG A+ QL+ +G+ + +++R K G + D LA SCD A + Sbjct: 7 GGTGFIGTALTQLLNARGHEVTLVSR-----KPGPGRITWDELAASGLPSCDAAVNLAGE 61 Query: 65 NTFEELEK 72 N L + Sbjct: 62 NILNPLRR 69 >4ZRP-A nrPDB Length = 409 Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 18/34 (52%) Query: 187 KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP 220 + ++EE LK P G FG A+ FL+ SP Sbjct: 206 RTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSP 239 >3ORF-A nrPDB Length = 251 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 40/172 (23%), Positives = 66/172 (38%), Gaps = 24/172 (13%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAAAGDLGGDHLAFSCDVAK 59 M K V GGS +G V + K + +++ R A DH +F+ + Sbjct: 21 MSKNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNA---------DH-SFTIKDSG 70 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAG------INRDGLLVRTKTEDMVSQLHTNLLGSML 113 E ++++ E++ +V+ V AAG + D L K + NL + Sbjct: 71 EEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVK-----GMIDMNLYSAFA 125 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 + + + QGG V G+ L SG Y A+K + LA E Sbjct: 126 SAHIGAKLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASE 175 >5AOG-A nrPDB Length = 307 Score = 27.7 bits (60), Expect = 4.2, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 86 INRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ 145 +NR+GL T +D+ S T L + R Q S+V +G I L G GQ Sbjct: 240 VNREGLF--TSDQDLFSNARTRALVDKFA--RSQRDFFDQFAFSVVKMGQIKVLTGTQGQ 295 >1C0L-A nrPDB Length = 363 Score = 27.3 bits (59), Expect = 5.2, Method: Compositional matrix adjust. Identities = 13/28 (46%), Positives = 20/28 (71%) Query: 10 GSRGIGRAVAQLMARKGYRLAVIARNLE 37 GS IG + A ++ARKGY + ++AR+L Sbjct: 13 GSGVIGLSSALILARKGYSVHILARDLP 40 >5N2I-A nrPDB Length = 232 Score = 27.3 bits (59), Expect = 6.3, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 26/42 (61%) Query: 6 AVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG 47 AV GG+ GR +A+ A G+ + + +R+ E A+A A +LG Sbjct: 23 AVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELG 64 >2CF5-A nrPDB Length = 357 Score = 26.9 bits (58), Expect = 8.5, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 18/35 (51%) Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDG 90 +V K V FE LEK+ R F+V+ G N D Sbjct: 323 EVVKMDYVNTAFERLEKNDVRYRFVVDVEGSNLDA 357 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4CQM-B nrPDB 315 8e-87 2PNF-A nrPDB 288 1e-78 3OSU-A nrPDB 279 6e-76 3RSH-A nrPDB 278 1e-75 2C07-A nrPDB 276 4e-75 4JRO-A nrPDB 274 2e-74 3EMK-A nrPDB 272 1e-73 2UVD-A nrPDB 270 3e-73 1Q7C-A nrPDB 270 3e-73 5CDY-A nrPDB 266 6e-72 3LYL-A nrPDB 266 6e-72 3FTP-A nrPDB 265 1e-71 3WOH-A nrPDB 263 4e-71 4DMM-A nrPDB 263 6e-71 2HQ1-A nrPDB 263 7e-71 3F9I-A nrPDB 260 5e-70 3GRP-A nrPDB 260 5e-70 4RZH-A nrPDB 257 3e-69 4M8S-A nrPDB 255 1e-68 2NM0-A nrPDB 255 1e-68 4BO1-A nrPDB 254 2e-68 3O4R-A nrPDB 249 8e-67 2CDH-G nrPDB 248 1e-66 5ITV-A nrPDB 248 2e-66 6NRP-A nrPDB 246 7e-66 2PH3-A nrPDB 245 1e-65 2ZAT-A nrPDB 245 2e-65 4KMS-A nrPDB 243 4e-65 4IIN-A nrPDB 243 4e-65 5OVL-A nrPDB 243 4e-65 4K6F-A nrPDB 242 1e-64 3AUT-A nrPDB 241 1e-64 3EZL-A nrPDB 240 3e-64 3VZS-A nrPDB 239 8e-64 1GEG-A nrPDB 238 1e-63 5OVJ-A nrPDB 238 2e-63 4CQL-A nrPDB 235 1e-62 5VT6-A nrPDB 235 2e-62 1GEE-A nrPDB 234 2e-62 2EW8-A nrPDB 233 5e-62 1UZM-A nrPDB 232 8e-62 4RZI-B nrPDB 232 1e-61 4NBT-A nrPDB 232 1e-61 1NFF-A nrPDB 231 2e-61 1YXM-A nrPDB 230 3e-61 1AE1-A nrPDB 230 3e-61 5T5Q-A nrPDB 230 4e-61 5U9P-A nrPDB 230 6e-61 6CI9-A nrPDB 230 6e-61 4NBV-A nrPDB 230 7e-61 4DBZ-A nrPDB 228 1e-60 3OEC-A nrPDB 228 1e-60 2AE2-A nrPDB 227 3e-60 4IIV-A nrPDB 225 1e-59 3WYE-A nrPDB 225 2e-59 1K2W-A nrPDB 222 1e-58 3V2H-A nrPDB 222 1e-58 4Z9Y-A nrPDB 221 2e-58 3W8F-A nrPDB 221 3e-58 2CFC-A nrPDB 220 3e-58 3OIC-A nrPDB 220 4e-58 3V2G-A nrPDB 220 4e-58 4IS3-A nrPDB 219 5e-58 5OJG-A nrPDB 219 6e-58 2Q2Q-A nrPDB 219 8e-58 5YSS-A nrPDB 219 8e-58 1X1T-A nrPDB 218 2e-57 2HSD-A nrPDB 217 3e-57 1O5I-A nrPDB 217 4e-57 4E6P-A nrPDB 216 6e-57 3R3S-A nrPDB 216 6e-57 1AHH-A nrPDB 215 1e-56 3WTC-A nrPDB 214 2e-56 3UN1-A nrPDB 214 3e-56 3U5T-A nrPDB 214 4e-56 3RWB-A nrPDB 213 5e-56 5B1Y-A nrPDB 213 7e-56 4MOW-A nrPDB 211 2e-55 4FC7-A nrPDB 211 3e-55 3UVE-A nrPDB 209 8e-55 2B4Q-A nrPDB 209 9e-55 4AVY-A nrPDB 209 1e-54 3A28-C nrPDB 208 1e-54 4HP8-A nrPDB 207 3e-54 1DOH-A nrPDB 206 6e-54 3T7C-A nrPDB 204 3e-53 3UF0-A nrPDB 202 9e-53 2O23-A nrPDB 202 9e-53 5JS6-A nrPDB 202 1e-52 1HXH-A nrPDB 201 2e-52 3D3W-A nrPDB 201 3e-52 1H5Q-A nrPDB 200 4e-52 2GDZ-A nrPDB 200 5e-52 3GDF-A nrPDB 199 6e-52 5EJ2-A nrPDB 199 9e-52 3V8B-A nrPDB 197 3e-51 3ZV3-A nrPDB 197 4e-51 1E3W-A nrPDB 197 4e-51 4TRR-A nrPDB 195 1e-50 1CYD-A nrPDB 195 1e-50 3U4C-A nrPDB 195 2e-50 2FWM-X nrPDB 194 2e-50 2AG5-A nrPDB 194 3e-50 5JY1-A nrPDB 191 2e-49 5O3Z-A nrPDB 189 8e-49 1BDB-A nrPDB 188 2e-48 5IZ4-A nrPDB 183 9e-47 4RGB-A nrPDB 181 3e-46 4EGF-A nrPDB 179 8e-46 4CR6-A nrPDB 179 1e-45 2X9N-A nrPDB 178 2e-45 4DA9-A nrPDB 178 2e-45 4ZJU-A nrPDB 178 2e-45 3OML-A nrPDB 178 3e-45 2BGM-A nrPDB 178 3e-45 1W73-A nrPDB 178 3e-45 3PXX-A nrPDB 175 1e-44 5TF4-A nrPDB 174 2e-44 2NWQ-A nrPDB 174 3e-44 4M89-A nrPDB 173 5e-44 4NR0-A nrPDB 171 2e-43 3GRK-A nrPDB 169 8e-43 4DRY-A nrPDB 169 8e-43 3K2E-A nrPDB 169 9e-43 5KOI-A nrPDB 168 2e-42 3PPI-A nrPDB 167 4e-42 3RKU-A nrPDB 166 5e-42 1P33-A nrPDB 166 6e-42 3OIG-A nrPDB 166 1e-41 1A27-A nrPDB 166 1e-41 4GKB-A nrPDB 165 1e-41 2QHX-A nrPDB 165 1e-41 5I9N-A nrPDB 165 2e-41 2BFA-A nrPDB 165 2e-41 6CGE-A nrPDB 164 2e-41 4ALL-A nrPDB 160 5e-40 3E9N-A nrPDB 157 2e-39 4HBG-A nrPDB 154 3e-38 2HRB-A nrPDB 153 5e-38 5ILO-A nrPDB 152 1e-37 3KZV-A nrPDB 148 2e-36 3UCF-A nrPDB 147 4e-36 1N5D-A nrPDB 145 1e-35 3BHI-A nrPDB 144 3e-35 2PD3-A nrPDB 144 5e-35 5PGZ-A nrPDB 139 7e-34 3DWF-A nrPDB 137 5e-33 3U9L-A nrPDB 134 3e-32 2DKN-A nrPDB 132 9e-32 4Z3K-A nrPDB 129 1e-30 4HWK-A nrPDB 129 1e-30 1OAA-A nrPDB 125 1e-29 1SNY-A nrPDB 123 7e-29 1B15-A nrPDB 116 8e-27 1FJH-A nrPDB 115 2e-26 1MG5-A nrPDB 110 4e-25 Sequences not found previously or not previously below threshold: 2P91-A nrPDB 179 1e-45 2YW9-A nrPDB 173 7e-44 5YCX-A nrPDB 166 9e-42 5CFZ-A nrPDB 163 6e-41 4JQC-A nrPDB 161 2e-40 4J3F-A nrPDB 154 3e-38 4NK4-A nrPDB 145 2e-35 5L51-A nrPDB 127 3e-30 3O26-A nrPDB 119 2e-27 2O2S-A nrPDB 112 1e-25 4Q9N-A nrPDB 112 1e-25 5LCX-A nrPDB 105 2e-23 1ENP-A nrPDB 104 2e-23 2NTV-A nrPDB 102 1e-22 5WQO-A nrPDB 100 7e-22 2PTG-A nrPDB 100 1e-21 4OYR-A nrPDB 99 2e-21 3F4B-A nrPDB 95 3e-20 5TQV-A nrPDB 91 4e-19 2O2Y-A nrPDB 82 2e-16 3SLK-A nrPDB 75 2e-14 4LIS-A nrPDB 68 3e-12 3ORF-A nrPDB 63 8e-11 2PK3-A nrPDB 63 9e-11 6BWL-A nrPDB 57 5e-09 3RFT-A nrPDB 56 1e-08 1UDA-A nrPDB 55 2e-08 1OOE-A nrPDB 54 4e-08 1Z45-A nrPDB 54 6e-08 1DIR-A nrPDB 51 5e-07 1I3M-A nrPDB 50 7e-07 2GN9-A nrPDB 50 7e-07 2Q1W-A nrPDB 49 1e-06 2NNL-D nrPDB 48 4e-06 4PVC-A nrPDB 47 6e-06 3HFS-A nrPDB 46 1e-05 1VL0-A nrPDB 46 1e-05 3ENK-A nrPDB 46 1e-05 3SC6-A nrPDB 46 1e-05 4G5H-A nrPDB 46 2e-05 4J2O-A nrPDB 45 4e-05 4R1T-A nrPDB 44 4e-05 5N2I-A nrPDB 44 6e-05 1GPJ-A nrPDB 43 1e-04 4R1U-A nrPDB 43 1e-04 1OC2-A nrPDB 43 1e-04 5YWN-A nrPDB 42 2e-04 1ZZE-A nrPDB 42 2e-04 1GY8-A nrPDB 42 2e-04 2PZM-A nrPDB 42 2e-04 4QUK-A nrPDB 42 3e-04 1R66-A nrPDB 41 3e-04 5B6K-A nrPDB 41 5e-04 4EJ0-A nrPDB 41 5e-04 1RPN-A nrPDB 40 6e-04 6ACF-A nrPDB 40 0.001 1KEU-A nrPDB 39 0.002 6GCS-E nrPDB 39 0.002 5F5N-A nrPDB 39 0.002 2C20-A nrPDB 39 0.002 2HUN-A nrPDB 38 0.003 2Q4B-A nrPDB 38 0.003 5K1S-A nrPDB 37 0.005 4WPG-A nrPDB 37 0.008 4KTT-E nrPDB 37 0.009 1BXK-A nrPDB 36 0.011 3VPX-A nrPDB 36 0.011 1LU9-A nrPDB 36 0.011 4EUF-A nrPDB 36 0.013 2P4H-X nrPDB 35 0.021 1ZDL-A nrPDB 35 0.022 4EJ6-A nrPDB 35 0.031 5ENV-A nrPDB 35 0.038 2HK7-A nrPDB 35 0.040 2GGS-A nrPDB 34 0.046 6ACQ-A nrPDB 34 0.052 3PVZ-A nrPDB 34 0.053 1MLD-A nrPDB 34 0.055 5INT-A nrPDB 34 0.059 3PEF-A nrPDB 34 0.061 3IP1-A nrPDB 34 0.062 1O89-A nrPDB 34 0.063 1EQ2-A nrPDB 34 0.068 2X86-A nrPDB 34 0.071 4K28-A nrPDB 34 0.073 3OND-A nrPDB 34 0.076 3VR3-A nrPDB 34 0.082 4WLE-A nrPDB 34 0.082 6C6P-A nrPDB 33 0.092 3LK7-A nrPDB 33 0.093 2EXX-A nrPDB 33 0.10 4J6F-A nrPDB 33 0.12 4B4O-A nrPDB 33 0.12 2C54-A nrPDB 33 0.12 1DB3-A nrPDB 33 0.13 4KDR-A nrPDB 33 0.14 5U9C-A nrPDB 32 0.16 4KDC-A nrPDB 32 0.16 1ML4-A nrPDB 32 0.18 4Z6K-A nrPDB 32 0.18 2GAS-A nrPDB 32 0.19 3BIC-A nrPDB 32 0.20 1QYD-A nrPDB 32 0.20 1JPH-A nrPDB 32 0.22 6BMQ-A nrPDB 32 0.22 4WOK-A nrPDB 32 0.23 3DMF-A nrPDB 32 0.24 6G2J-P nrPDB 32 0.26 3R9I-A nrPDB 32 0.27 1JAY-A nrPDB 32 0.29 3WMX-A nrPDB 32 0.30 1C0L-A nrPDB 32 0.31 4N18-A nrPDB 32 0.32 4UUP-A nrPDB 32 0.32 3DQQ-A nrPDB 32 0.34 3F6S-A nrPDB 31 0.40 3K6J-A nrPDB 31 0.47 1HE4-A nrPDB 31 0.47 4BKP-A nrPDB 31 0.49 2VN8-A nrPDB 31 0.50 4J90-A nrPDB 31 0.55 2EER-A nrPDB 30 0.59 5VXO-A nrPDB 30 0.65 3MFY-A nrPDB 30 0.67 1U3W-A nrPDB 30 0.76 3NJ4-A nrPDB 30 0.92 5BUT-A nrPDB 30 0.93 2V6G-A nrPDB 30 0.95 5BN5-A nrPDB 30 0.96 6MVR-A nrPDB 30 1.00 2HMT-A nrPDB 30 1.0 4GBJ-A nrPDB 30 1.1 3DOJ-A nrPDB 30 1.1 6BI4-A nrPDB 30 1.1 3PII-A nrPDB 30 1.1 2CF5-A nrPDB 30 1.2 3X2F-A nrPDB 29 1.4 5JXW-A nrPDB 29 1.4 5UZH-A nrPDB 29 1.5 5GXF-A nrPDB 29 1.5 4E0B-A nrPDB 29 1.5 4AP9-A nrPDB 29 1.6 7REQ-A nrPDB 29 1.6 1YXY-A nrPDB 29 1.6 6BII-A nrPDB 29 1.8 3H0K-A nrPDB 29 1.8 5NUE-A nrPDB 29 1.8 4RQU-A nrPDB 29 1.9 5GUP-L nrPDB 29 1.9 1VPD-A nrPDB 29 2.1 3RI6-A nrPDB 29 2.3 6C55-A nrPDB 29 2.3 4W5U-B nrPDB 29 2.3 6DEB-A nrPDB 29 2.6 5U5G-A nrPDB 29 2.7 4YUC-A nrPDB 28 3.0 1ZCJ-A nrPDB 28 3.1 3N58-A nrPDB 28 3.1 2RIR-A nrPDB 28 3.2 1LLU-A nrPDB 28 3.2 3S2F-A nrPDB 28 3.2 5VM2-A nrPDB 28 3.3 5LBA-B nrPDB 28 3.4 5LB8-A nrPDB 28 3.4 1NHQ-A nrPDB 28 3.6 3H9U-A nrPDB 28 3.8 5L6F-A nrPDB 28 3.9 3ZWA-A nrPDB 28 3.9 3ZU2-A nrPDB 28 3.9 2QYS-A nrPDB 28 4.0 3TWO-A nrPDB 28 4.2 2X3N-A nrPDB 28 4.2 1YB5-A nrPDB 28 4.2 4XRR-A nrPDB 28 4.3 3NT2-A nrPDB 28 4.3 3DC2-A nrPDB 28 4.4 1LEH-A nrPDB 28 4.4 1QQV-A nrPDB 28 4.5 6GBN-A nrPDB 28 4.7 1IE3-A nrPDB 27 5.2 5YZ0-C nrPDB 27 5.2 4D3S-A nrPDB 27 5.4 3QWB-A nrPDB 27 5.5 6H5E-B nrPDB 27 5.8 4Y4N-A nrPDB 27 5.9 3CJR-A nrPDB 27 6.5 5EVM-A nrPDB 27 6.7 3K96-A nrPDB 27 6.8 3K4W-A nrPDB 27 6.8 4MIT-A nrPDB 27 6.9 3JTJ-A nrPDB 27 7.0 1HSZ-A nrPDB 27 7.0 1ZK7-A nrPDB 27 7.1 5JH1-A nrPDB 27 7.5 4DLL-A nrPDB 27 7.6 5HC7-A nrPDB 27 7.8 3RHA-A nrPDB 27 8.0 5A3V-A nrPDB 27 8.1 5C1C-A nrPDB 27 8.2 3CGD-A nrPDB 27 8.2 2BC1-A nrPDB 27 8.4 2A9F-A nrPDB 27 8.6 4TSK-A nrPDB 27 8.7 3G1U-A nrPDB 27 8.7 5OCM-A nrPDB 27 8.8 5YDP-A nrPDB 27 9.0 2O0B-A nrPDB 27 9.0 1HRD-A nrPDB 27 9.3 1VIM-A nrPDB 27 9.6 4A5O-A nrPDB 27 9.7 >4CQM-B nrPDB Length = 244 Score = 315 bits (809), Expect = 8e-87, Method: Composition-based stats. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE Sbjct: 8 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 67 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR Sbjct: 68 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 127 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF Sbjct: 128 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 187 Query: 181 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL 237 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL Sbjct: 188 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL 244 >2PNF-A nrPDB Length = 248 Score = 288 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 102/240 (42%), Positives = 143/240 (59%), Gaps = 9/240 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVA 58 KV V G +RGIGRA+A+ +A G + + + E AKA A ++ G ++ Sbjct: 8 KVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMNLL 67 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E + FEE+ + ++ LVN AGI RD L +R D L NL G+ L + + Sbjct: 68 SEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVTQNS 127 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 +R MI+Q+ G IVN+ S+VG GN GQ YS +K GL+GF+++LAKE+A + + VN VAP Sbjct: 128 LRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAP 187 Query: 179 GFVHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ TDMT L EE K+ IPLGRFG EVA+ V+FL + YITG V+ V+GG+ Sbjct: 188 GFIETDMTAVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITGEVIHVNGGM 247 >3OSU-A nrPDB Length = 246 Score = 279 bits (715), Expect = 6e-76, Method: Composition-based stats. Identities = 94/244 (38%), Positives = 145/244 (59%), Gaps = 9/244 (3%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDL---GGDHLAFSCD 56 M K V G SRGIGR++A +A +GY +AV + E A+A ++ G D A + Sbjct: 3 MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQAN 62 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 VA +V+ +E+ G ++ LVN AGI RD LL+R K ++ + TNL G + Sbjct: 63 VADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQ 122 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A M++Q+ G+I+N+ S+VG GN GQ+ Y A+K G++G +++ A+E+A + I VN V Sbjct: 123 KATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAV 182 Query: 177 APGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDG 231 APGF+ +DMT L + E + IPL RFG+ ++A+ V FL + YITG + V+G Sbjct: 183 APGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNG 242 Query: 232 GLQL 235 G+ + Sbjct: 243 GMYM 246 >3RSH-A nrPDB Length = 251 Score = 278 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 98/239 (41%), Positives = 148/239 (61%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G SRGIG+A+A+L+A +G ++ A + GA+A + LG + + +V Sbjct: 13 KVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPES 72 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 ++ + + G V+ LVN AGI RD LL+R K E+ + TNL KA +R M Sbjct: 73 IEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGM 132 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+NVGS+VG GN+GQ+ Y+A+K G++GF++++A+EVA + + VN VAPGF+ Sbjct: 133 MKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIE 192 Query: 183 TDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 TDMTK L +E +P GR G+ E+A AV FL + YITG L V+GG+ +I Sbjct: 193 TDMTKALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGETLHVNGGMYMI 251 >2C07-A nrPDB Length = 285 Score = 276 bits (708), Expect = 4e-75, Method: Composition-based stats. Identities = 91/241 (37%), Positives = 139/241 (57%), Gaps = 8/241 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +KV V G RGIGR +A+++A+ + I+R + + ++ G + ++ DV+ Sbjct: 44 NKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVS 103 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 K+ ++ ++ V+ LVN AGI RD L +R K ++ L TNL + Sbjct: 104 KKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPI 163 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + MI + G I+N+ SIVGL GN GQ+ YS+SK G++GF+++LAKE+A + I VN +AP Sbjct: 164 SKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAP 223 Query: 179 GFVHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ +DMT + E+ ++ NIP GR G EVA+ FL S YI G V V+DGGL Sbjct: 224 GFISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGL 283 Query: 234 Q 234 Sbjct: 284 S 284 >4JRO-A nrPDB Length = 271 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 103/242 (42%), Positives = 145/242 (59%), Gaps = 9/242 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA----RNLEGAKAAAGDLGGDHLAFSCDVA 58 KV V GGSRGIGR +A +A++G + E + G + A +VA Sbjct: 30 KVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAMKANVA 89 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 DV F++ + GRV+ LVN AGI RD LL+R K ++ ++ NL G+ L KA Sbjct: 90 IAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFLCTKAV 149 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 RTM++Q+ G I+N+ S+VGL GN+GQ+ Y ASK G++G ++ A+E+A + I VN VAP Sbjct: 150 SRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGINVNAVAP 209 Query: 179 GFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ TDMT L E E + IPLG +G T ++A+AV+FL S YITG L VDGG+ Sbjct: 210 GFITTDMTDKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYITGQTLSVDGGM 269 Query: 234 QL 235 + Sbjct: 270 VM 271 >3EMK-A nrPDB Length = 246 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 87/239 (36%), Positives = 137/239 (57%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 + V G + G+G A+A+ + +G + + E K A +LG F +++ Sbjct: 8 RKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDREA 67 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 V+ ++ E+ +G V+ LVN AGI RDGL VR ED + L NL + M Sbjct: 68 VKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTRELTHPM 127 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+N+ SIVG+ GN GQ+ Y ASK GL+GFS++LA+E+A + + VN +APGF+ Sbjct: 128 MRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAPGFIE 187 Query: 183 TDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 + MT L E + + NIP+ R G ++A AVV+L + Y+TG L V+GG+ +I Sbjct: 188 SAMTGKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTLHVNGGMAMI 246 >2UVD-A nrPDB Length = 246 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 103/242 (42%), Positives = 145/242 (59%), Gaps = 9/242 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGD---LGGDHLAFSCDVA 58 KV V G SRGIGRA+A +A++G + V N + A + LG D +A DVA Sbjct: 5 KVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRADVA 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 DV N ++ G+V+ LVN AG+ +D LL+R K E+ + ++TNL G L KA Sbjct: 65 NAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLCTKAV 124 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 R M++Q+ G IVN+ S+VG+ GN GQ+ Y A+K G++G ++ AKE+A + I VN +AP Sbjct: 125 SRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNAIAP 184 Query: 179 GFVHTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ TDMT L E + K IP +FGE ++A+AV F S YITG L VDGG+ Sbjct: 185 GFIATDMTDVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYITGQTLNVDGGM 244 Query: 234 QL 235 + Sbjct: 245 VM 246 >1Q7C-A nrPDB Length = 244 Score = 270 bits (691), Expect = 3e-73, Method: Composition-based stats. Identities = 98/239 (41%), Positives = 148/239 (61%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K+ V G SRGIGRA+A+ +A +G ++ A + GA+A + LG + +V Sbjct: 6 KIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPAS 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 +++ E++ G V+ LVN AGI RD LL+R K E+ + TNL KA MR M Sbjct: 66 IESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAM 125 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+ +GS+VG GN GQ+ ++A+K GL+GFS++LA+EVA + I VNVVAPGF+ Sbjct: 126 MKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIE 185 Query: 183 TDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 TDMT+ L ++ + +P GR G E+A+AV FL + YITG L V+GG+ ++ Sbjct: 186 TDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGGMYMV 244 >5CDY-A nrPDB Length = 244 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 95/239 (39%), Positives = 143/239 (59%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K+ V G SRGIGRA+A+L+ +G + A + +GA+A + LG + +V Sbjct: 6 KIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTS 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + + G V+ LVN AGI RD LL+R K ++ + TNL KA MR M Sbjct: 66 IDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVMRAM 125 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+ +GS+VG GN+GQ Y+A+K G++GFS++LA+EVA + I VNVVAPGF+ Sbjct: 126 MKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVAPGFIE 185 Query: 183 TDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 TDMT+ L ++ + +P R G+ E+A AV FL + YI+G L V+GG+ +I Sbjct: 186 TDMTRTLTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGETLHVNGGMYMI 244 >3LYL-A nrPDB Length = 247 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 93/242 (38%), Positives = 139/242 (57%), Gaps = 8/242 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA---GDLGGDHLAFSCDVA 58 +KV V G SRGIG VA +A KG + A + A+ + G +++ Sbjct: 5 EKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNIS 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +QN F E++ ++ LVN AGI RD L++R ++ S ++TNL K Sbjct: 65 DIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSKEC 124 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 +R M++++ G I+++GS+VG GN GQ+ Y A+K G++GFS++LA EVA + I VNVVAP Sbjct: 125 VRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNVVAP 184 Query: 179 GFVHTDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ TDMT L +E + IP G+ GE ++A AV FL + YITG L V+GG+ Sbjct: 185 GFIATDMTDKLTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITGQTLHVNGGM 244 Query: 234 QL 235 + Sbjct: 245 YM 246 >3FTP-A nrPDB Length = 270 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 104/248 (41%), Positives = 140/248 (56%), Gaps = 13/248 (5%) Query: 1 MDK-----VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK---AAAGDLGGDHLA 52 MDK V V G SRGIGRA+A +AR+G + A GA+ AA G + Sbjct: 22 MDKTLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRG 81 Query: 53 FSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112 +V V E K G +N LVN AGI +D L +R K ++ + + TNL Sbjct: 82 AVLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVF 141 Query: 113 LTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 172 +A +R M++ +GG IVN+ S+VG GN GQ Y+A+K G+ G +RALA+E+ + I Sbjct: 142 RLSRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGIT 201 Query: 173 VNVVAPGFVHTDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 227 VN VAPGF+ TDMTK L +E LK IPLGR G ++AHAV FL + YITG L Sbjct: 202 VNCVAPGFIDTDMTKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITGTTL 261 Query: 228 VVDGGLQL 235 V+GG+ + Sbjct: 262 HVNGGMFM 269 >3WOH-A nrPDB Length = 251 Score = 263 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 98/240 (40%), Positives = 148/240 (61%), Gaps = 7/240 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI----ARNLEGAKAAAGDLGGDHLAFSCDVA 58 KV V GGSRG+GRA+A +AR G +A++ + + + LGG ++ CDV+ Sbjct: 12 KVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRCDVS 71 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 V + + LG V+ LVN AGI RDGL K ED + ++TNL G+ L KA Sbjct: 72 DAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLFIKAC 131 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 I+++ GSI+N+ S+ G+ G++GQ+ Y+++K GL+G ++++AKE+A + +R N VAP Sbjct: 132 YFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNAVAP 191 Query: 179 GFVHTDMTKDLKEEHLK-KNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 235 G + TDMT+DL ++ + +P+ RFG EVA V FL ES YITG V+ VDGG+ + Sbjct: 192 GLIATDMTQDLVDDSKRLDPVPMRRFGRPDEVAGLVAFLAGDESSYITGQVVCVDGGMAM 251 >4DMM-A nrPDB Length = 269 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 104/241 (43%), Positives = 146/241 (60%), Gaps = 7/241 (2%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF----SCDV 57 D++ V G SRGIGRA+A +A G ++AV + GA DV Sbjct: 28 DRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKADV 87 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++E +V+ F + + GR++ LVN AGI RD LL+R K +D S L NL G L +A Sbjct: 88 SQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCSRA 147 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A + M++Q+ G I+N+ S+VG GN GQ+ YSA+K G++G ++ +AKE+A + I VN VA Sbjct: 148 AAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNAVA 207 Query: 178 PGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL---ESPYITGHVLVVDGGLQ 234 PGF+ TDMT +L E L + IPLGR+GE EVA V FL + YITG V+ +DGGL Sbjct: 208 PGFIATDMTSELAAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYITGQVINIDGGLV 267 Query: 235 L 235 + Sbjct: 268 M 268 >2HQ1-A nrPDB Length = 247 Score = 263 bits (672), Expect = 7e-71, Method: Composition-based stats. Identities = 96/242 (39%), Positives = 138/242 (57%), Gaps = 9/242 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV----IARNLEGAKAAAGDLGGDHLAFSCDVA 58 K V G SRG+G+A+A + G + + + +L+ G + + DV Sbjct: 6 KTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKGDVK 65 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 DV+N + GR++ LVN AGI RD L+++ +D L+TNL + L KA Sbjct: 66 NPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYLCTKAV 125 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M++Q+ G I+N+ SI G+ GN+GQ+ Y+ASK GL+GF++++AKE A K I N VAP Sbjct: 126 SKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYCNAVAP 185 Query: 179 GFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 G + TDMT L + E NIPL RFG EVA+ V FL S YITG V+ +DGGL Sbjct: 186 GIIKTDMTDVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNYITGQVINIDGGL 245 Query: 234 QL 235 + Sbjct: 246 VM 247 >3F9I-A nrPDB Length = 249 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 88/239 (36%), Positives = 138/239 (57%), Gaps = 9/239 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G S GIG A+A+L+ + G ++ + N E K+ L ++ C++A + + Sbjct: 15 KTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLANKEE 74 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 N + ++ LV AGI D L +R K +D + NL + + + A++ M Sbjct: 75 CSNLISKTSN----LDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKM 130 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 IQ++ G I+N+ SIVG+ GN GQ+ Y ASK GL+G +++L+ EVA + I VN VAPGF+ Sbjct: 131 IQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGFIK 190 Query: 183 TDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 +DMT L E E + + IPLG +G +VA+AV FL + YITG L V+GG+ ++ Sbjct: 191 SDMTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTLHVNGGMLMV 249 >3GRP-A nrPDB Length = 266 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 87/239 (36%), Positives = 137/239 (57%), Gaps = 5/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 + V G + GIG A+A+ +G + + + K A DLG D FS +++ Sbjct: 28 RKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDRKS 87 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 ++ E E+ + ++ LVN AGI RDGL VR + +D L NL + + + +M Sbjct: 88 IKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSM 147 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 ++++ G I+N+ SIVG+ GN GQ+ Y A+K GL+GFS+ALA+E+A + I VN +APGF+ Sbjct: 148 MRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIAPGFIK 207 Query: 183 TDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 + MT L E E + IP+ R G E+A A V+L + Y+TG L ++GG+ +I Sbjct: 208 SAMTDKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTGQTLHINGGMAMI 266 >4RZH-A nrPDB Length = 247 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 96/240 (40%), Positives = 144/240 (60%), Gaps = 7/240 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +V V G SRGIG+A A +A G ++ V A++ A A ++ GG+ +A +VA Sbjct: 7 QVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQANVA 66 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +V + R++ LVN AGI RD LL+R K ED + + NL G L KA Sbjct: 67 NADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAV 126 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M++Q+ G I+N+ S+ G+ GN GQ+ YSA+K G++GF++ +AKE+A + + VN VAP Sbjct: 127 SKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAP 186 Query: 179 GFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL---ESPYITGHVLVVDGGLQL 235 GF+ TDMT++L E + + IPL R+G+ EVA + FL + YITG VDGG+ + Sbjct: 187 GFIATDMTENLNAEPILQFIPLARYGQPEEVAGTIRFLATDPAAAYITGQTFNVDGGMVM 246 >4M8S-A nrPDB Length = 248 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 97/239 (40%), Positives = 143/239 (59%), Gaps = 6/239 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG-DHLAFSCDVAKEH 61 K+ V G SRGIG A+A +A G ++ A + GA A + L + A+ Sbjct: 9 KIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSAEPE 68 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 V+N ++EK G+++ LVN AGI RD LL+R K E+ + NL KA +R Sbjct: 69 TVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKAVLRG 128 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M++Q+ G I+N+ S+VG+ GN+GQ+ Y+A+K GL+GFS+++A+EV + I VN VAPGF+ Sbjct: 129 MMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCVAPGFI 188 Query: 182 HTDMTKDLKEE---HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 TDMT+ L EE LGRFG+ ++A AV+FL + YITG L V+GG+ + Sbjct: 189 DTDMTRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQTLHVNGGMLM 247 >2NM0-A nrPDB Length = 253 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 99/240 (41%), Positives = 143/240 (59%), Gaps = 13/240 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 M + V GG+RGIG A+A+ A G ++A+ R+ E + LA CD+ Sbjct: 20 MSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEG--------FLAVKCDITDT 71 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V+ ++E+E+ G V L+ AG+ +D LL+R ED S + TNL G+ K A R Sbjct: 72 EQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANR 131 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 M++ + G +V + S+VGL G++GQ+ Y+ASK GLVGF+R+LA+E+ + I NVVAPGF Sbjct: 132 AMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGF 191 Query: 181 VHTDMTKDLKEEH---LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 V TDMTK L +E + +PLGR+ E+A V FL + YITG V+ VDGGL + Sbjct: 192 VDTDMTKVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGGLGM 251 >4BO1-A nrPDB Length = 269 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 103/241 (42%), Positives = 145/241 (60%), Gaps = 8/241 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 KV V G SRGIG+A+A + R G + A + GA+ A L G + DV+ Sbjct: 28 KVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSS 87 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + V T E +++HLG+ +VN AGI RD LLVR K ++ ++TNL KA + Sbjct: 88 DESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSKAVL 147 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 R M + + G I+N+GS+VG GN+GQ+ Y+A+K GL GF+RALA+EV + I VN VAPG Sbjct: 148 RGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPG 207 Query: 180 FVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 F+ TDMT++L E E L IPLGR G+ E+A V FL + Y+TG + V+GG+ Sbjct: 208 FIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMY 267 Query: 235 L 235 + Sbjct: 268 M 268 >3O4R-A nrPDB Length = 261 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 80/242 (33%), Positives = 121/242 (50%), Gaps = 11/242 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF---SCDVA 58 +KV V + GIG A+A+ +A+ G + V +R + A L G+ L+ C V Sbjct: 15 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 74 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 K D + K G ++ LV+ A +N G ++ E L N+ L KA Sbjct: 75 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 134 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + M ++ GGS+V V SI + G S Y+ SK L+G ++ LA E+A + IRVN +A Sbjct: 135 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 194 Query: 178 PGFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVD 230 PG + T ++ L KEE +K+ + + R GE + A V FL + YITG +VV Sbjct: 195 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVG 254 Query: 231 GG 232 GG Sbjct: 255 GG 256 >2CDH-G nrPDB Length = 244 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 97/244 (39%), Positives = 142/244 (58%), Gaps = 10/244 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGDL---GGDHLAFSCDV 57 V V G SRGIG+A+A + + G ++ V AR+ + A+ + + GG + F DV Sbjct: 1 SPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDV 60 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 +KE DV+ + G ++ +VN AGI RD LL+R K + NL G L +A Sbjct: 61 SKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQA 120 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A + M++++ G I+N+ S+VGL GN GQ+ Y+A+K G++GFS+ A+E A + I VNVV Sbjct: 121 ATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVC 180 Query: 178 PGFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLL---ESPYITGHVLVVDG 231 PGF+ +DMT L E+ KK IPLGR G+ VA V FL + YITG +DG Sbjct: 181 PGFIASDMTAKLGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQAFTIDG 240 Query: 232 GLQL 235 G+ + Sbjct: 241 GIAI 244 >5ITV-A nrPDB Length = 255 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 16/249 (6%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA-GDLGGDHLAFSCDVAKE 60 DK + GG+ GIG A Q + + V + +A + D+ E Sbjct: 7 DKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDE 66 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 Q+ E G ++ L+N AGI + + D L NL G L K A++ Sbjct: 67 AACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALK 126 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 M+ G+I+N S+ GL Y+ASKGG++ ++++A + A+ +IRVN V PG Sbjct: 127 HMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGI 186 Query: 181 VHTDM------------TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 + T + +++K+E K N PL R G+ E+A+ ++FL S Y+TG Sbjct: 187 IDTPLNEKSFLENNEGTLEEIKKEKAKVN-PLLRLGKPEEIANVMLFLASDLSSYMTGSA 245 Query: 227 LVVDGGLQL 235 + DGG Sbjct: 246 ITADGGYTA 254 >6NRP-A nrPDB Length = 263 Score = 246 bits (629), Expect = 7e-66, Method: Composition-based stats. Identities = 90/240 (37%), Positives = 130/240 (54%), Gaps = 7/240 (2%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARN-LEGAKAAAGD---LGGDHLAFSCD 56 M + V G SRGIG+A+A +A+ G+ + V AR+ A+ + LG + D Sbjct: 23 MTRRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFD 82 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 V + VQ E+ + G +V AG+ DG +D + T+L G K Sbjct: 83 VNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLK 142 Query: 117 AAMRTMIQ-QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + MI ++GG IV + S+ G+ GN GQ YSA+K GL+G ++ALA E+A++KI VN Sbjct: 143 PLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNC 202 Query: 176 VAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 VAPG + T+M D +EH K IPL R G+ EVA V FL + Y+T V+ V+GGL Sbjct: 203 VAPGLIETEMVTDEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVISVNGGL 262 >2PH3-A nrPDB Length = 245 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 102/242 (42%), Positives = 138/242 (57%), Gaps = 10/242 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA----RNLEGAKAAAGDLGGDHLAF-SCDV 57 + + G SRGIGRA+A +A G+ LA+ E A G +A ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + + + LG ++ LVN AGI RD LLVR K ED + L NL T + Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A++ M++ + G IVN+ S+VG+ GN GQ+ Y ASK GL+GF+RA+AKE A++ I VN VA Sbjct: 122 AVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVA 181 Query: 178 PGFVHTDMTKDLK---EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 PGF+ T+MT+ L +E K IP GRFG EVA AV FL+ + YITG L VDGG Sbjct: 182 PGFIETEMTERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCVDGG 241 Query: 233 LQ 234 L Sbjct: 242 LT 243 >2ZAT-A nrPDB Length = 260 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 74/242 (30%), Positives = 121/242 (50%), Gaps = 11/242 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF---SCDVA 58 +KV V + GIG A+A+ +A+ G + V +R E L G+ L+ C V Sbjct: 14 NKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVG 73 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 K D + G V+ LV+ A +N G ++ E LH N+ ++L KA Sbjct: 74 KAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKA 133 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + M ++ GGS++ V S+ Y+ SK L+G ++ LA E+A + IRVN +A Sbjct: 134 VVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLA 193 Query: 178 PGFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVD 230 PG + T+ ++ L ++E++K+++ + R G + A V FL + YITG +VV Sbjct: 194 PGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVVVG 253 Query: 231 GG 232 GG Sbjct: 254 GG 255 >4KMS-A nrPDB Length = 249 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 85/243 (34%), Positives = 132/243 (54%), Gaps = 9/243 (3%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIA-RNLEGAKAAAGDLGGDHLAFSCDVAK 59 M ++ V GG+RGIG+A A + KG + N + AK G + +VA Sbjct: 9 MSEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCW--NVAD 66 Query: 60 EHDVQNTFEELEKHLGR-VNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + + +E+E+ + V+ LVN AGI +D +L R +D ++ NL + Sbjct: 67 FEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSV 126 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 M M Q G IVN+ SI G GQ+ YSA+K G++GF++ALA+E A K I VN +AP Sbjct: 127 MEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAP 186 Query: 179 GFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 G++ T+M + E+ L K +IP R G+ E+A AV FL++ + +ITG + ++GG Sbjct: 187 GYIATEMVGAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGGH 246 Query: 234 QLI 236 +I Sbjct: 247 NMI 249 >4IIN-A nrPDB Length = 271 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 99/242 (40%), Positives = 139/242 (57%), Gaps = 9/242 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDL---GGDHLAFSCDVA 58 K + G S+GIG +A+ +A G ++ + R N E A A +L G D A Sbjct: 30 KNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAA 89 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E D + + + G +++LVN AG+ RD L ++ KTED + NL + + C+ A Sbjct: 90 SESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREA 149 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 ++ M + + GS+VNV SI+G +GN GQ+ YSASKGG++ S++ A E A + IR N V P Sbjct: 150 LKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRFNSVTP 209 Query: 179 GFVHTDMTKDLKEEHLK---KNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 GF+ TDM +LK+E KNIPL R G EVA AV FLL S YITG L V+GGL Sbjct: 210 GFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLKVNGGL 269 Query: 234 QL 235 + Sbjct: 270 YM 271 >5OVL-A nrPDB Length = 300 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 87/240 (36%), Positives = 133/240 (55%), Gaps = 13/240 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 + + V GG+RGIG A+A+ +A G+++AV R CDV Sbjct: 67 VSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL--------FGVQCDVTDS 118 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V F+E+E+H G V LV AGI++D L+R E ++TNL G+ + A R Sbjct: 119 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 178 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 TM +++ G I+ +GS+ G+ G Q+ Y+A+K GL+G +R++++E+A+ + NVVAPG+ Sbjct: 179 TMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGY 238 Query: 181 VHTDMTKDLKEEHLK---KNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 + T+MT+ L E IP R G EVA AV FL + YI G V+ VDGG+ + Sbjct: 239 IDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGMGM 298 >4K6F-A nrPDB Length = 255 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 80/243 (32%), Positives = 131/243 (53%), Gaps = 10/243 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDL---GGDHLAFSCDVA 58 ++ V GG G+G AV+ + G+R+ V N GA ++ G + A+ DVA Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVA 71 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 Q E++ + +G V+ LVN AGI RD L + + + + TNL K Sbjct: 72 DHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPV 131 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 M+++ G IVN+ S+ G KG+ GQ+ Y+A+K G+ GF+++LA E+ARK + VN V+P Sbjct: 132 CDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNTVSP 191 Query: 179 GFVHTDM----TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 G++ T M +D+ + + IP GR G+ EVA V +L + ++TG + ++GG Sbjct: 192 GYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAINGG 251 Query: 233 LQL 235 + Sbjct: 252 QHM 254 >3AUT-A nrPDB Length = 269 Score = 241 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 73/245 (29%), Positives = 120/245 (48%), Gaps = 12/245 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG----AKAAAGDLGGDHLAFSCDV 57 DKV + GGS G+GRA+A ++ ++ + N E AK + GG + DV Sbjct: 15 DKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQGDV 74 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 KE DV N + K G ++ ++N AG+ ++ + TNL G+ L + Sbjct: 75 TKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGSRE 134 Query: 118 AMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A++ ++ G+++N+ S+ + Y+ASKGG+ + LA E A K IRVN + Sbjct: 135 AIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNI 194 Query: 177 APGFVHTDMTKD-----LKEEHLKKNIPLGRFGETIEVAHAVVFLLES--PYITGHVLVV 229 PG ++T + + ++ ++ IP+G G+ EVA FL S Y+TG L Sbjct: 195 GPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFA 254 Query: 230 DGGLQ 234 DGG+ Sbjct: 255 DGGMT 259 >3EZL-A nrPDB Length = 256 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 127/242 (52%), Gaps = 9/242 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGD---LGGDHLAFSCDVA 58 ++ V GG GIG ++ Q + + G+R+ N D LG D A +V Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVG 73 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + F++++ +G ++ LVN AGI RD + + ED + + TNL K Sbjct: 74 DWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQV 133 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M+++ G I+N+ S+ G KG GQ+ YS +K G+ GF+ +LA+EVA K + VN V+P Sbjct: 134 IDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSP 193 Query: 179 GFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 G++ TDM K ++ + L+K IP+ R G E+ V +L S + TG ++GGL Sbjct: 194 GYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLNGGL 253 Query: 234 QL 235 + Sbjct: 254 HM 255 >3VZS-A nrPDB Length = 257 Score = 239 bits (610), Expect = 8e-64, Method: Composition-based stats. Identities = 82/242 (33%), Positives = 127/242 (52%), Gaps = 9/242 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV----IARNLEGAKAAAGDLGGDHLAFSCDVA 58 ++ V GG GIG A+ Q +A+ G+R+ + E LG D +A +VA Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + F++++ +G V+ L+N AGI RD + + D + + TNL K Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQV 134 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M + G IVN+ S+ G KG GQ+ YS +K GL GF+ ALA+EVA K + VN V+P Sbjct: 135 IDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSP 194 Query: 179 GFVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 G++ TDM K ++++ L K IP+ R G E+A +L S + TG ++GGL Sbjct: 195 GYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGGL 254 Query: 234 QL 235 + Sbjct: 255 HM 256 >1GEG-A nrPDB Length = 256 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 78/253 (30%), Positives = 121/253 (47%), Gaps = 20/253 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDV 57 M KV V G +GIG+A+A + + G+ +A+ N AKA A ++ GG +A DV Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + V E+ K LG + +VN AG+ + E + + N+ G + +A Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 118 AMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A+ ++ GG I+N S G GN +VYS+SK + G ++ A+++A I VN Sbjct: 121 AVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 177 APGFVHTDMTKDLKEE--------------HLKKNIPLGRFGETIEVAHAVVFLLE--SP 220 PG V T M ++ + K I LGR E +VA V +L S Sbjct: 181 CPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSD 240 Query: 221 YITGHVLVVDGGL 233 Y+TG L++DGG+ Sbjct: 241 YMTGQSLLIDGGM 253 >5OVJ-A nrPDB Length = 256 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 87/240 (36%), Positives = 133/240 (55%), Gaps = 13/240 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 + + V GG+RGIG A+A+ +A G+++AV R CDV Sbjct: 23 VSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL--------FGVQCDVTDS 74 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V F+E+E+H G V LV AGI++D L+R E ++TNL G+ + A R Sbjct: 75 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 134 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 TM +++ G I+ +GS+ G+ G Q+ Y+A+K GL+G +R++++E+A+ + NVVAPG+ Sbjct: 135 TMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGY 194 Query: 181 VHTDMTKDLKEEHLK---KNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 + T+MT+ L E IP R G EVA AV FL + YI G V+ VDGG+ + Sbjct: 195 IDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGMGM 254 >4CQL-A nrPDB Length = 261 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 84/248 (33%), Positives = 131/248 (52%), Gaps = 17/248 (6%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG----------DHLAFS 54 V G GIGRAV+ +A +G +A + A+ LGG +H AF Sbjct: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 Query: 55 CDVAKEHDVQNTFEELEKHLGRV-NFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 DV++ + E+++ R + +V+ AGI +D L+ +D + NL G+ L Sbjct: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 Query: 114 TCKAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 172 +AA + ++ GSI+N+ SIVG GN GQ+ Y+ASK G++G ++ A+E+ R IR Sbjct: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 Query: 173 VNVVAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 227 N V PGF+ T MT+ + + + + + IP+G G+ +VA V FL S YITG + Sbjct: 194 CNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSV 253 Query: 228 VVDGGLQL 235 V GGL + Sbjct: 254 EVTGGLFM 261 >5VT6-A nrPDB Length = 269 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 75/243 (30%), Positives = 130/243 (53%), Gaps = 10/243 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAA----AGDLGGDHLAFSCDVA 58 +V V GG G+G A+++ + G +AV + D G D A++ DVA Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVA 85 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + E++ G+V+ L+N AGI RD ++ D + + T+L K Sbjct: 86 DFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQF 145 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M++++ G IVN+GS+ G +G GQ+ Y+++K G+ GF++ LA E A++ I VN V+P Sbjct: 146 IAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTVSP 205 Query: 179 GFVHTDMTKDLKEEHLKK----NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 G++ T M + + ++ L+ IP+GR G EVA + FL + ++TG L ++GG Sbjct: 206 GYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLAINGG 265 Query: 233 LQL 235 + + Sbjct: 266 MHM 268 >1GEE-A nrPDB Length = 261 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 70/245 (28%), Positives = 117/245 (47%), Gaps = 12/245 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG----AKAAAGDLGGDHLAFSCDVA 58 KV + G S G+G+++A A + ++ V R+ E +GG+ +A DV Sbjct: 8 KVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVT 67 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E DV N + K G+++ ++N AG+ D + TNL G+ L + A Sbjct: 68 VESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGSREA 127 Query: 119 MRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 ++ ++ G+++N+ S+ Y+ASKGG+ + LA E A K IRVN + Sbjct: 128 IKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIG 187 Query: 178 PGFVHTDMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLLES--PYITGHVLVVD 230 PG ++T + + + ++ IP+G GE E+A +L S Y+TG L D Sbjct: 188 PGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEASYVTGITLFAD 247 Query: 231 GGLQL 235 GG+ L Sbjct: 248 GGMTL 252 >2EW8-A nrPDB Length = 249 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 71/240 (29%), Positives = 112/240 (46%), Gaps = 8/240 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDLGGDHLAFSCDVAKE 60 DK+ + GG+ GIGRA+A+ A +G +A+ A+AA +LG L CDV++ Sbjct: 7 DKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDVSQP 66 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 DV+ +++ GR + LVN AGI E N+ L KA + Sbjct: 67 GDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMAKAFVP 126 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 M + G I+N+ S + Y ++K +GF+RALA ++ + I VN +AP Sbjct: 127 GMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAIAPSL 186 Query: 181 VHTDMTKDLKEEHLKKNIP-----LGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 V T T+ + +P + R +++ A FL + +ITG L VDGG+ Sbjct: 187 VRTATTEASALSAMFDVLPNMLQAIPRLQVPLDLTGAAAFLASDDASFITGQTLAVDGGM 246 >1UZM-A nrPDB Length = 247 Score = 232 bits (593), Expect = 8e-62, Method: Composition-based stats. Identities = 84/240 (35%), Positives = 131/240 (54%), Gaps = 13/240 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 + + V GG+RGIG A+AQ +A G+++AV R K DV Sbjct: 14 VSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL--------FGVEVDVTDS 65 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V F +E+H G V LV+ AG++ D L+R E ++ NL G+ + A R Sbjct: 66 DAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASR 125 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 +M + + G ++ +GS+ GL G Q+ Y+ASK G++G +R++A+E+++ + NVVAPG+ Sbjct: 126 SMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGY 185 Query: 181 VHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 + TDMT+ L E + + IP R G EVA V FL + YI+G V+ VDGG+ + Sbjct: 186 IDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGM 245 >4RZI-B nrPDB Length = 240 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 88/239 (36%), Positives = 128/239 (53%), Gaps = 13/239 (5%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 DKV V GG+RGIG A+ +L+ G ++A +G + L +V Sbjct: 8 DKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT-------EALGVVANVTDLE 60 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + E+ LG V +V AGI +D + D + L+ NL G + K + Sbjct: 61 SMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEG 120 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M +++ GSIV + SI G +GN GQ+ YSA+K G++G ++LA+E AR +R N VAPGF+ Sbjct: 121 MYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFI 180 Query: 182 HTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE---SPYITGHVLVVDGGLQ 234 T+MT ++E E + K IP RFG+ E+A AV FLL S Y+TG VL V+G Sbjct: 181 DTEMTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVNGAHH 239 >4NBT-A nrPDB Length = 240 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 75/246 (30%), Positives = 126/246 (51%), Gaps = 25/246 (10%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS------CD 56 KV + GG++G+G+A+A A +G ++ AGDLG + + Sbjct: 7 KVAVITGGAKGLGQAIALAYAEEGAKVI------------AGDLGDLTYSHPNVEGMYLN 54 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 V V+ ++ + G+++ LVN AGI +D + + + + NL G + Sbjct: 55 VTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTR 114 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK--IRVN 174 M GSI+N+ S+VG+ GN GQ+ Y+A+K G++G + AKE A K +RVN Sbjct: 115 LVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVN 174 Query: 175 VVAPGFVHTDMTKDLKEEHLKKNIP---LGRFGETIEVAHAVVFLLE--SPYITGHVLVV 229 +APG++ TD+ K + ++ L K L R G+ E+A +FL + Y+TG + V Sbjct: 175 AIAPGYIMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTINV 234 Query: 230 DGGLQL 235 +GG++L Sbjct: 235 NGGMRL 240 >1NFF-A nrPDB Length = 260 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 76/232 (32%), Positives = 111/232 (47%), Gaps = 4/232 (1%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V GG+RG+G + + M +G ++ E KA A +L DV + Sbjct: 8 KVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVTQPAQ 67 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + + G ++ LVN AGI G + + L NL G L +A ++ M Sbjct: 68 WKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRAVVKPM 127 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 + GSI+N+ SI GL G Y+A+K + G +++ A E+ IRVN + PG V Sbjct: 128 KEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHPGLVK 187 Query: 183 TDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 T MT + E+ LGR E +EV++ VV+L S Y TG VVDGG Sbjct: 188 TPMTDWVPEDIF--QTALGRAAEPVEVSNLVVYLASDESSYSTGAEFVVDGG 237 >1YXM-A nrPDB Length = 303 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 75/251 (29%), Positives = 119/251 (47%), Gaps = 20/251 (7%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG--------DHLAFS 54 +V V GG+ GIG+A+ + + G + + +R LE K+AA +L + Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 C++ E +V N + G++NFLVN G ++ + L TNL G+ Sbjct: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 CKA + +++ GGSIVN+ + G A++ G+ +++LA E A IR+N Sbjct: 139 CKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 Query: 175 VVAPGFVHTDMT--------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITG 224 VAPG +++ + E +K IP R G EV+ V FLL + +ITG Sbjct: 198 CVAPGVIYSQTAVENYGSWGQSFFEGSFQK-IPAKRIGVPEEVSSVVCFLLSPAASFITG 256 Query: 225 HVLVVDGGLQL 235 + VDGG L Sbjct: 257 QSVDVDGGRSL 267 >1AE1-A nrPDB Length = 273 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 71/247 (28%), Positives = 113/247 (45%), Gaps = 15/247 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKA---AAGDLGGDHLAFSCDVAKE 60 V GGS+GIG A+ + +A G R+ +RN + + G + CD+ Sbjct: 23 TALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSR 82 Query: 61 HDVQNTFEELEKHL-GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + + + G++N LVN AG+ +D + TN + + A Sbjct: 83 TERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAY 142 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + Q G+++ + SI G S+YSASKG + +++LA E A+ IRVN VAPG Sbjct: 143 PLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPG 202 Query: 180 FVHTDMTKDL--KEEHLKKNI-------PLGRFGETIEVAHAVVFLL--ESPYITGHVLV 228 + T + + K H K+ I P+GR G+ EV+ + FL + YITG ++ Sbjct: 203 VILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYITGQIIW 262 Query: 229 VDGGLQL 235 DGG Sbjct: 263 ADGGFTA 269 >5T5Q-A nrPDB Length = 247 Score = 230 bits (587), Expect = 4e-61, Method: Composition-based stats. Identities = 72/241 (29%), Positives = 117/241 (48%), Gaps = 10/241 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG--DHLAFSCDVAK 59 ++ + G + GIGRA+A+L G L + + EG A A LG D + Sbjct: 9 NRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASS 68 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 D + T + G ++FLV +AGI + D + NL G CK A+ Sbjct: 69 ADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCKRAL 128 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + + SIV + S+ +G + Y A+KG +V +RAL++E+A K RVN V+PG Sbjct: 129 PALKEDS--SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TRVNGVSPG 185 Query: 180 FVHTDMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 + T MT +L + + + PL R G+ E+A + FL + ++TG + V+GG+ Sbjct: 186 IIETPMTSELLKTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGETIQVNGGIY 245 Query: 235 L 235 + Sbjct: 246 M 246 >5U9P-A nrPDB Length = 265 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 72/242 (29%), Positives = 117/242 (48%), Gaps = 10/242 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG---DLGGDHLAFSCDVAK 59 + + G RGIG +A+ +A G + + RN E A A D G DVA+ Sbjct: 21 RRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVFDVAE 80 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 V+ +E E +G ++ LVN AGI R L + +D + + NL G +A Sbjct: 81 HAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVAQAVA 140 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 R MI + G I+N+ S+ + Y+A+KG + ++ + + AR I+ N +APG Sbjct: 141 RHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQANGLAPG 200 Query: 180 FVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLESP--YITGHVLVVDGG 232 + T++ + L + + L K P GR+G+ E+ A +FL + ++ G L VDGG Sbjct: 201 YFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFVNGQTLFVDGG 260 Query: 233 LQ 234 L Sbjct: 261 LT 262 >6CI9-A nrPDB Length = 259 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 116/239 (48%), Gaps = 9/239 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG---DHLAFSCDVAK 59 + V GGS+GIGR +A+ A G + + RN + DL G A DV Sbjct: 10 RSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTD 69 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 D + T E G ++ + AGI G L +D+ L N G++ +AA+ Sbjct: 70 PEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAAL 129 Query: 120 RTMIQQQGGSIVNVGSIVG-LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + + G +V SI G + G G S Y ASK +GF R A E+A KKI +N V P Sbjct: 130 QALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLP 189 Query: 179 GFVHTDMTKDLKEEHLKKN---IPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 232 G + T+ ++ +++L + IP GR G ++ +A +F E+ Y+TG LVVDGG Sbjct: 190 GNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGG 248 >4NBV-A nrPDB Length = 246 Score = 230 bits (586), Expect = 7e-61, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 116/241 (48%), Gaps = 8/241 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSC---DVAK 59 +V + G + GIG A AQ A G + + + AA L S DV + Sbjct: 6 RVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRVDVTR 65 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 +V + RV+ LVN AGI +D L + + + NL G +A Sbjct: 66 RDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNCAQAVA 125 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 M +Q G I+N S+VGL GN GQ+ Y+ASK G++GF++ A+E+ K +RVN V PG Sbjct: 126 GLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVNAVCPG 185 Query: 180 FVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 FV+T++ + + + + + + L R E E+A FL + Y+ G + GG+ Sbjct: 186 FVNTEILQTVPDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVNGVAIEASGGMS 245 Query: 235 L 235 L Sbjct: 246 L 246 >4DBZ-A nrPDB Length = 281 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 21/253 (8%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVA 58 +V V G + GIG +A+ + ++G R+ V AR EG + +L G + +CDV Sbjct: 26 SEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVR 85 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +++ + + G V+ LVN AG G E + + TNL G K Sbjct: 86 SVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQV 145 Query: 119 MRT--MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 ++ M+++ G IVN+ S G +G + YSASK G+VGF++AL E+AR I VN V Sbjct: 146 LKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAV 205 Query: 177 APGFVHTDMTKDLKE--------------EHLKKNIPLGRFGETIEVAHAVVFLL--ESP 220 PGFV T M ++E + + +P+GR+ + EVA V +L+ + Sbjct: 206 CPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPGAA 265 Query: 221 YITGHVLVVDGGL 233 +T L V GGL Sbjct: 266 AVTAQALNVCGGL 278 >3OEC-A nrPDB Length = 317 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 86/268 (32%), Positives = 126/268 (47%), Gaps = 40/268 (14%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR------------NLEGAKA---AAGDLG 47 KV + G +RG GR A +A+ G + I + E K + G Sbjct: 47 KVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVEEQG 106 Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN 107 +A DV +Q +E G ++ LV+ GI+ G +V + L TN Sbjct: 107 RRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDILQTN 166 Query: 108 LLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 166 L+G+ C+A + +MI++ QGGS++ V S VGL+G GQS Y+ASK G+ G +LA EV Sbjct: 167 LIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSLANEV 226 Query: 167 ARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIP--------------------LGRFGET 206 R IRVN V PG V+T+M L E+ LK +P + E Sbjct: 227 GRHNIRVNSVNPGAVNTEM--ALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIPWVEP 284 Query: 207 IEVAHAVVFLLE--SPYITGHVLVVDGG 232 +V++AV +L + YI G + VDGG Sbjct: 285 EDVSNAVAWLASDEARYIHGAAIPVDGG 312 >2AE2-A nrPDB Length = 260 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 71/246 (28%), Positives = 110/246 (44%), Gaps = 14/246 (5%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAKE 60 V GGSRGIG + + +A G + +RN + G A CD++ Sbjct: 11 TALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCDLSSR 70 Query: 61 HDVQNTFEELEKHL-GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + Q + H G++N LVN AGI ED + N + A Sbjct: 71 SERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLSVLAH 130 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + + G++V + S+ G ++VY A+KG + +R LA E A+ IRVN V PG Sbjct: 131 PFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNGVGPG 190 Query: 180 FVHTDMTK-DLKEEHLKKNI-------PLGRFGETIEVAHAVVFLL--ESPYITGHVLVV 229 + T + + +++ K+N+ L R GE E+A V FL + Y+TG ++ V Sbjct: 191 VIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASYVTGQIIYV 250 Query: 230 DGGLQL 235 DGGL Sbjct: 251 DGGLMA 256 >4IIV-A nrPDB Length = 267 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 80/242 (33%), Positives = 127/242 (52%), Gaps = 9/242 (3%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIA-RNLEGAKAAAGDL---GGDHLAFSCD 56 M + V G S+GIGRA+A+ +A G+ + V R+ GA+ + GG+ S D Sbjct: 25 MSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFD 84 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 VA + E G +V+ AGI RD +D + +HTNL + Sbjct: 85 VANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQ 144 Query: 117 AAMRTMI-QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + MI +QGG I+ + S+ G+ GN GQ YSA+K G++G ++ALA E+A++KI VN Sbjct: 145 PCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNC 204 Query: 176 VAPGFVHTDMT--KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDG 231 +APG + T M ++ + IP+ R G+ EVA +L+ + Y+T V+ ++G Sbjct: 205 IAPGLIDTGMIEMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQVISING 264 Query: 232 GL 233 G+ Sbjct: 265 GM 266 >3WYE-A nrPDB Length = 256 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 78/253 (30%), Positives = 119/253 (47%), Gaps = 20/253 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDV 57 M KV V G +GIG+A+A + + G+ +A+ N AKA A ++ GG +A DV Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + V E+ K LG + +VN AGI + L+ ED+ N+ +A Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 120 Query: 118 AMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A+ ++ GG I+N SI ++G S YS +K + G ++ A+++A I VN Sbjct: 121 AVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 177 APGFVHTDMTKDLKEE--------------HLKKNIPLGRFGETIEVAHAVVFLLE--SP 220 PG V T M + + E +I LGR +VA V FL S Sbjct: 181 CPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSD 240 Query: 221 YITGHVLVVDGGL 233 Y+TG L++DGG+ Sbjct: 241 YMTGQSLLIDGGM 253 >1K2W-A nrPDB Length = 256 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 71/250 (28%), Positives = 115/250 (46%), Gaps = 17/250 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G +RGIGRA A+ R+G R+A+ NLE A+A A ++G A + DV + Sbjct: 6 KTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVTDQAS 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + EL G ++ LVN A + +V E N+ G++ +A R M Sbjct: 66 IDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQAVARAM 125 Query: 123 IQ-QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 I +GG I+N+ S G +G + VY A+K ++ +++ + R I VN +APG V Sbjct: 126 IAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAIAPGVV 185 Query: 182 HTD--------------MTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGH 225 + + + K+ + +P GR G ++ +FL E+ YI Sbjct: 186 DGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEADYIVAQ 245 Query: 226 VLVVDGGLQL 235 VDGG + Sbjct: 246 TYNVDGGNWM 255 >3V2H-A nrPDB Length = 281 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 110/257 (42%), Gaps = 22/257 (8%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG-----AKAAAGDLGGDHLAFSC 55 M K + G + GIG A+A+ +A+ G + + AG G L Sbjct: 24 MTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPA 83 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 D+ K ++ + + G + LVN AG+ + E + NL S T Sbjct: 84 DMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTI 143 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + A+ M ++ G I+N+ S GL + +S Y A+K G++G ++ +A EVA + VN Sbjct: 144 RGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNS 203 Query: 176 VAPGFVHTDMTKD---------------LKEEHLKKNIPLGRFGETIEVAHAVVFLL--E 218 + PG+V T + + + E + K P +F +VA ++L + Sbjct: 204 ICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDD 263 Query: 219 SPYITGHVLVVDGGLQL 235 + ITG + +DGG Sbjct: 264 AAQITGTHVSMDGGWTA 280 >4Z9Y-A nrPDB Length = 253 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 67/240 (27%), Positives = 113/240 (47%), Gaps = 9/240 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLA-VIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 KV + G G+G+ +A +A+ G + V + LG L+ + D++ Sbjct: 11 KVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADMSNVS 70 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 E+ G V+ LVN AGI R + ++ ++ N+ + R Sbjct: 71 GHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQTVARQ 130 Query: 122 MIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 I+Q GG I+N+ S++ +G Y+ASK ++G +R +A E A+ I VN +APG+ Sbjct: 131 FIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNAIAPGY 190 Query: 181 VHTDMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLLESP--YITGHVLVVDGGL 233 + T+ T+ L+ + + IP GR+G ++ VFL S YI G+ + VDGG Sbjct: 191 MATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYINGYTIAVDGGW 250 >3W8F-A nrPDB Length = 260 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 64/255 (25%), Positives = 108/255 (42%), Gaps = 22/255 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA----RNLEGAKAAAG-DLGGDHLAFSCDV 57 K V G + GIG A+A +A+ G + + ++E ++ G + D+ Sbjct: 5 KKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADL 64 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + ++ + + LG ++ LVN AGI + + + + NL A Sbjct: 65 SDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAA 124 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A+ M +Q G I+N+ S GL + +S Y A+K G+VG ++ A E A K I N + Sbjct: 125 ALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCNAIC 184 Query: 178 PGFVHTDMT---------------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPY- 221 PG+V T + + E L + P +F ++ A VFL + Sbjct: 185 PGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSAAAD 244 Query: 222 -ITGHVLVVDGGLQL 235 +TG L +DGG Sbjct: 245 QMTGTTLSLDGGWTA 259 >2CFC-A nrPDB Length = 250 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 78/250 (31%), Positives = 116/250 (46%), Gaps = 14/250 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD----LGGDHLAFSCD 56 M +V V G S G G A+A +G R+A + + E + A L D Sbjct: 1 MSRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRAD 60 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGIN---RDGLLVRTKTEDMVSQLHTNLLGSML 113 VA E DV + G ++ LVN AGI G+L T E + N+ G L Sbjct: 61 VADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFL 120 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 C+A + M+ Q G IVN+ S+ L G+S Y+ SKG ++ ++++A + A IR Sbjct: 121 GCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRC 180 Query: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHV 226 N V PG + T MT+ + + + IP G +VA AV+FL ++ Y+ G Sbjct: 181 NAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNGAA 240 Query: 227 LVVDGGLQLI 236 LV+DG I Sbjct: 241 LVMDGAYTAI 250 >3OIC-A nrPDB Length = 258 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 67/247 (27%), Positives = 117/247 (47%), Gaps = 11/247 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAV-IARNLEGAKAAAGD---LGGDHLAFSCDV 57 +K V G SRG+G+A A +A GY + + AR+ + A A + LG L +V Sbjct: 4 NKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANV 63 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + ++ F+++++ GR++ VN A ++ + ++ N + + Sbjct: 64 GQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQE 123 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A + M + GG IV++ S+ ++ + SK L +R LA E++ K+I VN V+ Sbjct: 124 AAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVS 183 Query: 178 PGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLES--PYITGHVLVVD 230 G + TD K E ++N P GR E ++ V FL+ S I G ++VD Sbjct: 184 GGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIVD 243 Query: 231 GGLQLIL 237 GG L++ Sbjct: 244 GGRSLLV 250 >3V2G-A nrPDB Length = 271 Score = 220 bits (561), Expect = 4e-58, Method: Composition-based stats. Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 11/242 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL-EGAKAAAGDL---GGDHLAFSCDVA 58 K V GGSRGIG A+A+ +A +G +A+ N E A+A ++ GG +A D Sbjct: 32 KTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIRADNR 91 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 ++ E + LG ++ LVN+AGI L T D + N + ++A Sbjct: 92 DAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFVAIRSA 151 Query: 119 MRTMIQQQGGSIVNVGS-IVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 R + GG I+ +GS + L G S+YSASK L G ++ LA+++ + I VN+V Sbjct: 152 SRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGITVNIVH 209 Query: 178 PGFVHTDMTKDLKE--EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 PG TDM + E ++ I G +GE ++A V +L + ++TG L +DGG Sbjct: 210 PGSTDTDMNPADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQGKFVTGASLTIDGGA 269 Query: 234 QL 235 Sbjct: 270 NA 271 >4IS3-A nrPDB Length = 268 Score = 219 bits (560), Expect = 5e-58, Method: Composition-based stats. Identities = 72/243 (29%), Positives = 117/243 (48%), Gaps = 10/243 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG-----DHLAFSCD 56 DKV + GG+RGIG A A++ G ++++ E A L + L F+ D Sbjct: 25 DKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPD 84 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 + V ++ + GR++ ++N AGI + + R E+ + N+ G Sbjct: 85 LTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVFNGAW 144 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A + M + G I+N S+ G+ G+ Y ASK ++G + L +E+ RK IRV V Sbjct: 145 CAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIRVVGV 204 Query: 177 APGFVHTDMTKDLKEEHLK---KNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDG 231 APG V+TDMT E ++ K +P+ R E E+A+ +FL + IT + VDG Sbjct: 205 APGVVNTDMTNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASDLASGITATTVSVDG 264 Query: 232 GLQ 234 + Sbjct: 265 AYR 267 >5OJG-A nrPDB Length = 260 Score = 219 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 15/248 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA----FSCDVA 58 KV V ++GIG A+A+ + +G + + +RN + A L L + +A Sbjct: 11 KVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIA 70 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 D + + + G++N LVN GIN G ++ + N+ K Sbjct: 71 STDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKL 130 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + ++ GG+I+ S K G + Y +K LVG +RALA +A+ IRVN +A Sbjct: 131 VHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIA 190 Query: 178 PGFVHTDMTKDL--------KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 227 PG + T M++ L KE + I LGR G + A V +L S YITG ++ Sbjct: 191 PGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMI 250 Query: 228 VVDGGLQL 235 ++ GG+Q Sbjct: 251 IIAGGVQA 258 >2Q2Q-A nrPDB Length = 255 Score = 219 bits (559), Expect = 8e-58, Method: Composition-based stats. Identities = 62/248 (25%), Positives = 105/248 (42%), Gaps = 17/248 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDLGGDHLAFSCDVAKEH 61 K V G + GIG +AQ++AR G + + + A A G + D++ Sbjct: 5 KTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLSDVA 64 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 ++ F E+ G V+ LVN AGI + + E + NL + A+ Sbjct: 65 QIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLALPG 124 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M + G I+N+ S+ GL G++G++ Y A+K G+VG ++ + E A + N + PG+V Sbjct: 125 MRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICPGWV 184 Query: 182 HTDMTKDLKEEH--------------LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGH 225 T + + ++ L + P F + V+FL + G Sbjct: 185 LTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQVRGA 244 Query: 226 VLVVDGGL 233 VDGG Sbjct: 245 AWNVDGGW 252 >5YSS-A nrPDB Length = 256 Score = 219 bits (559), Expect = 8e-58, Method: Composition-based stats. Identities = 61/248 (24%), Positives = 109/248 (43%), Gaps = 17/248 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDLGGDHLAFSCDVAKEH 61 K V G + GIG +AQ++A+ G L + +++ AK A G D++ E Sbjct: 6 KTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADLSDEA 65 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + + E G V+ L+N AGI + + + + NL T + A+ Sbjct: 66 QIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTRLALPG 125 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M + G I+N+ S+ GL + +S Y A+K G+VG ++ +A E A+ +I N + PG+V Sbjct: 126 MRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNALCPGWV 185 Query: 182 HTDMTK--------------DLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGH 225 T + + ++ L + P F ++ + +FL + + G Sbjct: 186 LTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGAAQVRGV 245 Query: 226 VLVVDGGL 233 +DGG Sbjct: 246 AWNMDGGW 253 >1X1T-A nrPDB Length = 260 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 74/255 (29%), Positives = 114/255 (44%), Gaps = 22/255 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI----ARNLEGAKA-AAGDLGGDHLAFSCDV 57 KV V G + GIG +A +A +G + + A +E +A A G L D+ Sbjct: 5 KVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDGADL 64 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 +K V+ + + +GR++ LVN AGI L+ TE + L NL A Sbjct: 65 SKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHGTAA 124 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A+ M +Q G I+N+ S GL ++ +S Y A+K G+VGF++ A E A + I N + Sbjct: 125 ALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITANAIC 184 Query: 178 PGFVHTDMTKD---------------LKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SP 220 PG+V T + + E L + P +F ++ VFL + Sbjct: 185 PGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLASDAAA 244 Query: 221 YITGHVLVVDGGLQL 235 ITG + VDGG Sbjct: 245 QITGTTVSVDGGWTA 259 >2HSD-A nrPDB Length = 253 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 87/237 (36%), Positives = 112/237 (47%), Gaps = 5/237 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + GG+RG+G A+ G R+ + E A A +LG DV E D Sbjct: 6 KTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEED 65 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 Q + G V+ LVN AGI+ L E + NL G + K + M Sbjct: 66 WQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAM 125 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 GGSIVN+ S GL G + S Y ASK G+ G S+ A E+ +IRVN V PG + Sbjct: 126 KDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTY 185 Query: 183 TDMTKDL---KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 T MT + + E N P+GR GE E+A AVV LL S Y+TG L VDGG Sbjct: 186 TPMTAETGIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGAELAVDGGWT 242 >1O5I-A nrPDB Length = 249 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 119/239 (49%), Gaps = 18/239 (7%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 DK V SRGIGRAVA +++++G + + ARN E K + H CD+ K+ Sbjct: 19 DKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSG------HRYVVCDLRKDL 72 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 D+ FE++++ V+ LV AG + G ED + + L + + + Sbjct: 73 DL--LFEKVKE----VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPA 126 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 M ++ G IV + S + ++++ L GF + L+ EVA I VN VAPG+ Sbjct: 127 MKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWT 186 Query: 182 HTDMTKDL----KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 T+ K+L K++ ++ IP+ R + E+A V FL + Y+TG +VVDGGL Sbjct: 187 ETERVKELLSEEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVDGGLS 245 >4E6P-A nrPDB Length = 259 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 119/250 (47%), Gaps = 17/250 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G +RGIGRA A+ R+G +A+ ++E A+ AA ++G A DV ++ Sbjct: 9 KSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDVTRQDS 68 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + +H G ++ LVN A + +V E N+ G++ T +AA R M Sbjct: 69 IDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQAAARQM 128 Query: 123 IQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 I Q +GG I+N+ S G +G + ++Y A+K ++ +++ ++ + +I VN +APG V Sbjct: 129 IAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAIAPGVV 188 Query: 182 HTDMTKDL--------------KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGH 225 + + K+ + + +P GR G ++ +FL S YI Sbjct: 189 DGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAESDYIVSQ 248 Query: 226 VLVVDGGLQL 235 VDGG + Sbjct: 249 TYNVDGGNWM 258 >3R3S-A nrPDB Length = 294 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 69/247 (27%), Positives = 108/247 (43%), Gaps = 15/247 (6%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG-----AKAAAGDLGGDHLAFSCD 56 D+ V GG GIGRA A AR+G +A+ E KA + G + D Sbjct: 49 DRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLLPGD 108 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGL-LVRTKTEDMVSQLHTNLLGSMLTC 115 ++ E ++ + + LG ++ L AG + +E N+ Sbjct: 109 LSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFWIT 168 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + A+ + + G SI+ SI + + Y+A+K ++ +SR LAK+VA K IRVN+ Sbjct: 169 QEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNI 226 Query: 176 VAPGFVHTDM-----TKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLV 228 VAPG + T + K + P+ R G+ E+A V+L S Y+T V Sbjct: 227 VAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHG 286 Query: 229 VDGGLQL 235 V GG L Sbjct: 287 VCGGEHL 293 >1AHH-A nrPDB Length = 255 Score = 215 bits (548), Expect = 1e-56, Method: Composition-based stats. Identities = 63/239 (26%), Positives = 105/239 (43%), Gaps = 10/239 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD---LGGDHLAFSCDVAK 59 K + G GIG+ +A A G + V N + A + LGG A CD+ Sbjct: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 E ++ + LG+V+ LVN AG D N+ + Sbjct: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 M + GG I+ + S+ N + Y++SK R +A ++ K IRVN +APG Sbjct: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 Query: 180 FVHTDMTKDL----KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 + TD K + E+ + ++ P+ R G+ ++A+A +FL + +++G +L V GG Sbjct: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 >3WTC-A nrPDB Length = 262 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 69/251 (27%), Positives = 120/251 (47%), Gaps = 20/251 (7%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD---LGGDHLAFSCDVAK 59 K+ AV G ++GIG+A+A +A+ G + ++ + A + LG +A + D++ Sbjct: 9 KIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTADISN 68 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 ++T + K LG ++ +VN AGI + ++ + ++ N+ G + +AA Sbjct: 69 RDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLWGMQAAA 128 Query: 120 RTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 ++ G I+N SI G +G YSA+K + +++ AKE+A I VN P Sbjct: 129 TLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITVNSYCP 188 Query: 179 GFVHTDMTKDLKEEHLK--------------KNIPLGRFGETIEVAHAVVFLLES--PYI 222 G V TDM + + + + I LGR +VA V +L S Y+ Sbjct: 189 GIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLSSSDADYM 248 Query: 223 TGHVLVVDGGL 233 TG +++DGGL Sbjct: 249 TGQSVLIDGGL 259 >3UN1-A nrPDB Length = 260 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 71/235 (30%), Positives = 111/235 (47%), Gaps = 8/235 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV + G S+GIG + + + YR+ +R+++ + D + D++K Sbjct: 29 KVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSAD------PDIHTVAGDISKPET 82 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 E + GR++ LVN AG+ V ED L N+ G + A M Sbjct: 83 ADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAEM 142 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSAS--KGGLVGFSRALAKEVARKKIRVNVVAPGF 180 ++Q G IV++ + + + G AS KGGL +R+LA E +R +RVN V+PG Sbjct: 143 LKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNAVSPGV 202 Query: 181 VHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQL 235 + T M L P+GR GE +V AV++L + +ITG +L VDGG Sbjct: 203 IKTPMHPAETHSTLAGLHPVGRMGEIRDVVDAVLYLEHAGFITGEILHVDGGQNA 257 >3U5T-A nrPDB Length = 267 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 76/243 (31%), Positives = 113/243 (46%), Gaps = 14/243 (5%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA----GDLGGDHLAFSCDV 57 +KV V G SRGIG A+A +A G+ + + A GG L DV Sbjct: 27 NKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQADV 86 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + V+ F E+ G V+ LVN AGI + T + NL G+ T + Sbjct: 87 SDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNTLRE 146 Query: 118 AMRTMIQQQGGSIVNVG-SIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A + + + GG I+N+ S VGL + +Y+A+K G+ + L+KE+ + I VN V Sbjct: 147 AAQRL--RVGGRIINMSTSQVGLL-HPSYGIYAAAKAGVEAMTHVLSKELRGRDITVNAV 203 Query: 177 APGFVHTDMT----KDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVD 230 APG TD+ D + K PL R G ++A AV FL + ++ G VL + Sbjct: 204 APGPTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNGQVLRAN 263 Query: 231 GGL 233 GG+ Sbjct: 264 GGI 266 >3RWB-A nrPDB Length = 247 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 70/238 (29%), Positives = 110/238 (46%), Gaps = 7/238 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G ++GIG+A+A +A G + V N EGAKAAA +G A + D++ Sbjct: 7 KTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPGS 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 V+ F E++ G ++ LVN A I + + NL G+ + +A M Sbjct: 67 VKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRAGTDQM 126 Query: 123 IQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 G ++++ S G + Y A+KGG++GF+RALA E+ + I N V PG + Sbjct: 127 RAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAVTPGLI 186 Query: 182 HTDMTKDLKEEHLKKNI----PLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 +D K + + G+ +A V FL + +ITG L VD G+ Sbjct: 187 ESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARWITGQTLNVDAGM 244 >5B1Y-A nrPDB Length = 270 Score = 213 bits (542), Expect = 7e-56, Method: Composition-based stats. Identities = 85/242 (35%), Positives = 119/242 (49%), Gaps = 14/242 (5%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARN----LEGAKAAAGDLGG-DHLAFSCDVAK 59 V GGSRGIGRA AR+G+ + + ++ E A LG + DV Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGD 85 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 V + + + +N LVNAAG+ + G + T + L NL G L K + Sbjct: 86 PDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTKLLL 145 Query: 120 RTMIQQQGGSIVNVGSIVGLKGN-SGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + + + SIVNV SI G GN YSASK G++G ++ LA ++A IRVN VAP Sbjct: 146 PLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAP 205 Query: 179 GFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLLE---SPYITGHVLVVD 230 FV TDMT+ K E + PL + +VA A++FL + S ITGHVL ++ Sbjct: 206 SFVETDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITGHVLSIN 265 Query: 231 GG 232 G Sbjct: 266 AG 267 >4MOW-A nrPDB Length = 256 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 79/244 (32%), Positives = 123/244 (50%), Gaps = 14/244 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARN----LEGAKAAAGDLGGDHLAFSCDVA 58 KV V G S+GIG A+A+ +A +G + V + + +A + GG +A DV+ Sbjct: 15 KVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGGDVS 74 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 K D Q + + GR++ LVN +G+ + E Q TN+ G +LT +AA Sbjct: 75 KAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLTTQAA 134 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 ++ + +G SI+N+ S+V +VYS +KG + + LA E+ +KIRVN + P Sbjct: 135 VKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVNAINP 192 Query: 179 GFVHTDMTKDLK------EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVD 230 G + T+ T E + PLGR GE ++A VFL + ++TG LVV Sbjct: 193 GMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARWMTGEHLVVS 252 Query: 231 GGLQ 234 GGL Sbjct: 253 GGLN 256 >4FC7-A nrPDB Length = 277 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 110/248 (44%), Gaps = 12/248 (4%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL----EGAKAAAGDLGGDHLAFSCDV 57 DKV + GG GIG +A++ R G + +R+L A+ AG G L S DV Sbjct: 27 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 86 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 V ++ K GR++ L+N A N + + + G+ + Sbjct: 87 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 146 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + GG IVN+ + +G +G + Q ++K + +R LA E + IRVN +A Sbjct: 147 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 206 Query: 178 PGFVH-TDMTKDLKEEHLK-----KNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVV 229 PG + T+ + L PL R G E+AH+V++L + Y+TG VLV Sbjct: 207 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 266 Query: 230 DGGLQLIL 237 DGG L Sbjct: 267 DGGAWLTF 274 >3UVE-A nrPDB Length = 286 Score = 209 bits (533), Expect = 8e-55, Method: Composition-based stats. Identities = 74/271 (27%), Positives = 111/271 (40%), Gaps = 41/271 (15%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA-------------------RNLEGAKAAA 43 KV V G +RG GR+ A +A++G + + +L Sbjct: 12 KVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETADLV 71 Query: 44 GDLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVR-TKTEDMVS 102 + DV ++ + + LGR++ +V AGI G + T ED Sbjct: 72 KGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWTE 131 Query: 103 QLHTNLLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRA 161 + NL G T KA + MI +GGSI+ S+ GLK Y A+K G+VG RA Sbjct: 132 MIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRA 191 Query: 162 LAKEVARKKIRVNVVAPGFVHTDMT----------KDLKEEHLKKNIPLGR--------F 203 E+ + IRVN V P V T M DL+ P+ + + Sbjct: 192 FGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPIPW 251 Query: 204 GETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 E I++++AV+F + YITG L +D G Sbjct: 252 VEPIDISNAVLFFASDEARYITGVTLPIDAG 282 >2B4Q-A nrPDB Length = 276 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 72/247 (29%), Positives = 116/247 (46%), Gaps = 14/247 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKE 60 ++ V GGSRGIG+ +AQ + G R+ + AR+ E A L GD A D++ E Sbjct: 30 RIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLSSE 89 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 + + L + R++ LVN AG + L + N+ + + Sbjct: 90 AGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQQLLP 149 Query: 121 TMIQQ----QGGSIVNVGSIVGLKGNSGQS-VYSASKGGLVGFSRALAKEVARKKIRVNV 175 + + ++N+GS+ G+ Q+ Y SK L SR LAKE+ + I VNV Sbjct: 150 LLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVGEHINVNV 209 Query: 176 VAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLES--PYITGHVLV 228 +APG + MT+ + E +IP+GR+G E+A + L + Y+TG+V+ Sbjct: 210 IAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAGAYMTGNVIP 269 Query: 229 VDGGLQL 235 +DGG L Sbjct: 270 IDGGFHL 276 >4AVY-A nrPDB Length = 242 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 83/236 (35%), Positives = 120/236 (50%), Gaps = 17/236 (7%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V GGS GIG A+A A G + + + +G A D+ +Q Sbjct: 14 VLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRH---PRIRREELDITDSQRLQ 70 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 FE L R++ LVN AGI+RD L NL +ML + A R ++ Sbjct: 71 RLFEALP----RLDVLVNNAGISRDR--EEYDLATFERVLRLNLSAAMLASQLA-RPLLA 123 Query: 125 QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTD 184 Q+GGSI+N+ S+ G++ + YSASKG +V +R+LA E A ++IRVN +APG++ T Sbjct: 124 QRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDTP 183 Query: 185 MTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233 + LK + + + PL R+GE EVA A FL + ++TG VL VDGG Sbjct: 184 LGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGGY 239 >3A28-C nrPDB Length = 258 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 77/255 (30%), Positives = 117/255 (45%), Gaps = 22/255 (8%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA-----GDLGGDHLAFSC 55 M KV V GG++GIGR +++ +A G+ +AV + +AA + Sbjct: 1 MSKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGL 60 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 DV + + + +E + LG + LVN AGI + L+ ED+ N+ Sbjct: 61 DVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGI 120 Query: 116 KAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 +AA R + G I+N SI ++G S YS +K + G ++A A+E+A K VN Sbjct: 121 QAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVN 180 Query: 175 VVAPGFVHTDMTKDLKEE--------------HLKKNIPLGRFGETIEVAHAVVFLLE-- 218 APG V T M + + E +I LGR +VA V FL Sbjct: 181 AYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASEN 240 Query: 219 SPYITGHVLVVDGGL 233 S Y+TG V++VDGG+ Sbjct: 241 SNYVTGQVMLVDGGM 255 >4HP8-A nrPDB Length = 247 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 117/240 (48%), Gaps = 14/240 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL-EGAKAAAGDLGGDHLAFSCDVAKEH 61 + V G + G+G+A+A +A G + AR + GG+ A D A Sbjct: 10 RKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFADPL 69 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 +++F + + LVN AGI R V D + NL T +A + Sbjct: 70 AAKDSFTDA-----GFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKE 124 Query: 122 MI-QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180 ++ + + G +VN+ S++ +G Y+A+K G+ G ++ LA E A K I VN +APG+ Sbjct: 125 LLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGY 184 Query: 181 VHTDMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFL--LESPYITGHVLVVDGGL 233 + T+ T+ L+ + + + IP GR+G + ++A A VFL + Y+ G +L VDGG Sbjct: 185 IETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILNVDGGW 244 >1DOH-A nrPDB Length = 283 Score = 206 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 120/256 (46%), Gaps = 25/256 (9%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARN----LEGAKAAAGDLGGDHLAFSCDVA 58 KV V G RGIGR +A + R+G ++ V N E AA G D +V Sbjct: 30 KVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVG 89 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 D+ FEE K G+++ + + +G+ G + E+ N G + A Sbjct: 90 VVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREA 149 Query: 119 MRTMIQQQGGSIVNVGSIVGL-KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + + + GG ++ +GSI G K +VYS SKG + F+R +A ++A KKI VNVVA Sbjct: 150 YKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITVNVVA 207 Query: 178 PGFVHTDMTKDLKEEHL----------------KKNIPLGRFGETIEVAHAVVFLLESP- 220 PG + TDM + E++ + PL R G I++A V FL + Sbjct: 208 PGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLASNDG 267 Query: 221 -YITGHVLVVDGGLQL 235 ++TG V+ +DGG + Sbjct: 268 GWVTGKVIGIDGGACM 283 >3T7C-A nrPDB Length = 299 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 78/270 (28%), Positives = 120/270 (44%), Gaps = 37/270 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA---------------RNLEGAKAAAGDLG 47 KV + G +RG GR+ A +AR+G + I +L LG Sbjct: 29 KVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALG 88 Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGL-LVRTKTEDMVSQLHT 106 +A DV +Q ++ LGR++ ++ A + +G L R + + Sbjct: 89 RRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMIDV 148 Query: 107 NLLGSMLTCKAAMRT-MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 NL G+ +T + A+ M ++GGSIV SI GL+G Y ASK GL G R +A E Sbjct: 149 NLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMALE 208 Query: 166 VARKKIRVNVVAPGFVHTDMT----------KDLKEEHLKKNIPLGR--------FGETI 207 + + IRVN+V P V T M DL+ ++ R + E Sbjct: 209 LGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIPYVEPA 268 Query: 208 EVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 ++++A++FL+ + YITG L VDGG L Sbjct: 269 DISNAILFLVSDDARYITGVSLPVDGGALL 298 >3UF0-A nrPDB Length = 273 Score = 202 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 77/241 (31%), Positives = 110/241 (45%), Gaps = 12/241 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 + V G GIGRA+A AR G + R +G K A ++ GG A D+A Sbjct: 32 RTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-DGVKEVADEIADGGGSAEAVVADLAD 90 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 N EEL RV+ LVN AGI L NL + + ++ Sbjct: 91 LEGAANVAEELAATR-RVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLSRSFG 149 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 M+ G IV + S++ +G + Y+ASK +VG +RALA E A + + VN +APG Sbjct: 150 TAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNALAPG 209 Query: 180 FVHTDMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232 +V T T L+ + + IP GR+ ++ VFL + Y+ G VL VDGG Sbjct: 210 YVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDAASYVHGQVLAVDGG 269 Query: 233 L 233 Sbjct: 270 W 270 >2O23-A nrPDB Length = 265 Score = 202 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 77/248 (31%), Positives = 118/248 (47%), Gaps = 16/248 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V + GG+ G+G A A+ + +G ++ G +A A LG + + DV E DV Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 73 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRT------KTEDMVSQLHTNLLGSMLTCKA 117 Q + GRV+ VN AGI ED L NL+G+ + Sbjct: 74 QTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRL 133 Query: 118 AMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A I Sbjct: 134 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 193 Query: 172 RVNVVAPGFVHTDMTKDLKEE---HLKKNIPL-GRFGETIEVAHAVVFLLESPYITGHVL 227 RV +APG T + L E+ L +P R G+ E AH V ++E+P++ G V+ Sbjct: 194 RVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVI 253 Query: 228 VVDGGLQL 235 +DG +++ Sbjct: 254 RLDGAIRM 261 >5JS6-A nrPDB Length = 274 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 66/228 (28%), Positives = 109/228 (47%), Gaps = 13/228 (5%) Query: 19 AQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVN 78 + G R+ + ++ G +A +L G + CDV +E DV+ E + GR++ Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVTQEDDVKTLVSETIRRFGRLD 86 Query: 79 FLVNAAGI-NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIV 137 +VN AG T + L NLLG+ K A+ + + Q G+++N+ S+V Sbjct: 87 CVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-GNVINISSLV 145 Query: 138 GLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKN 197 G G + Y A+KG + ++ALA + + +RVN ++PG + T + ++L Sbjct: 146 GAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPR 205 Query: 198 I---------PLGRFGETIEVAHAVVFLLE-SPYITGHVLVVDGGLQL 235 PLGR G+ EV A VFL + + TG L+V GG +L Sbjct: 206 ATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAEL 253 >1HXH-A nrPDB Length = 253 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 69/240 (28%), Positives = 110/240 (45%), Gaps = 13/240 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V GG+ G+G V +L+ +G ++A N + A +LG + DV+ E D Sbjct: 7 KVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSSEAD 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 +++ LG +N LVN AGI G + + ED L N + C+ + M Sbjct: 67 WTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQGIAAM 126 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK--IRVNVVAPGF 180 ++ GGSI+N+ S+ + YSASK + +RA A ++ IRVN + P Sbjct: 127 -KETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNSIHPDG 185 Query: 181 VHTDM-----TKDLKEEHLKKNIPLGRFGE---TIEVAHAVVFLLE--SPYITGHVLVVD 230 ++T M K + +E + + L R G +A V+FL S ++G L D Sbjct: 186 IYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDESSVMSGSELHAD 245 >3D3W-A nrPDB Length = 244 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 66/241 (27%), Positives = 101/241 (41%), Gaps = 13/241 (5%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 + V G +GIGR Q + G R+ ++R + + G D+ Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG-IEPVCVDLGDWEA 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + + G V+ LVN A + + E NL + + R + Sbjct: 67 TERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGL 122 Query: 123 IQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 181 I + G+IVNV S + + SVY ++KG L ++ +A E+ KIRVN V P V Sbjct: 123 IARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVV 182 Query: 182 HTDMTKD-----LKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQ 234 T M + K + + IPLG+F E V +A++FLL S TG L V+GG Sbjct: 183 MTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFW 242 Query: 235 L 235 Sbjct: 243 A 243 >1H5Q-A nrPDB Length = 265 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 81/254 (31%), Positives = 124/254 (48%), Gaps = 18/254 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGA----KAAAGDLGGDHLAFSCD 56 ++K V GG+RGIG A + +A G +AVI R+ A + + G A+ CD Sbjct: 13 VNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCD 72 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 V+ V T ++++ LG ++ L+ AG++ ED N+ G TC+ Sbjct: 73 VSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCR 132 Query: 117 AAMRTMI-QQQGGSIVNVGSI-------VGLKGNSGQSVYSASKGGLVGFSRALAKEVAR 168 A + + +QQ GSIV S+ L G+ Q Y++SK + LA E A Sbjct: 133 AVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEWAS 192 Query: 169 KKIRVNVVAPGFVHTDMTKDLKE---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYIT 223 IRVN ++PG+V+TD T + + +H NIPL RF + E+ + LL + Y+T Sbjct: 193 AGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDHATYMT 252 Query: 224 GHVLVVDGGLQLIL 237 G +DGG QLI Sbjct: 253 GGEYFIDGG-QLIW 265 >2GDZ-A nrPDB Length = 267 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 127/248 (51%), Gaps = 29/248 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG---AKAAAGD--LGGDHLAFSCDV 57 KV V G ++GIGRA A+ + KG ++A++ NLE KAA + L CDV Sbjct: 8 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCDV 67 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 A + +++TF ++ H GR++ LVN AG+N ++ L NL+ + Sbjct: 68 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISGTYL 119 Query: 118 AMRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRA--LAKEVARKKIR 172 + M +Q GG I+N+ S+ GL + Q VY ASK G+VGF+R+ LA + +R Sbjct: 120 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 179 Query: 173 VNVVAPGFVHTDMTKDLKEE-----------HLKKNIPLGRFGETIEVAHAVVFLLESPY 221 +N + PGFV+T + + +++E H+K I + +A+ ++ L+E Sbjct: 180 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 239 Query: 222 ITGHVLVV 229 + G ++ + Sbjct: 240 LNGAIMKI 247 >3GDF-A nrPDB Length = 267 Score = 199 bits (508), Expect = 6e-52, Method: Composition-based stats. Identities = 64/246 (26%), Positives = 105/246 (42%), Gaps = 15/246 (6%) Query: 3 KVCAVFGGS--RGIGRAVAQLMARKGYRLAVIARN-----LEGAKAAAGDLGGDHLAFSC 55 KV V G S +G+G A+ A G +A+ + E K G A+ C Sbjct: 21 KVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYKC 80 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 V + +++ G+++ + AG D ++ E + +L G+ Sbjct: 81 QVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNGTFHCA 140 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSG--QSVYSASKGGLVGFSRALAKEVARKKIRV 173 KA ++ GS+V S+ G N Q+ Y+ +K G + +R+LA E R RV Sbjct: 141 KAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW-RDFARV 199 Query: 174 NVVAPGFVHT---DMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLV 228 N ++PG++ T D ++ IP+GR G E+ A V+ S Y TG L+ Sbjct: 200 NSISPGYIDTGLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYFASDASTYTTGADLL 259 Query: 229 VDGGLQ 234 +DGG Sbjct: 260 IDGGYT 265 >5EJ2-A nrPDB Length = 308 Score = 199 bits (507), Expect = 9e-52, Method: Composition-based stats. Identities = 72/270 (26%), Positives = 113/270 (41%), Gaps = 37/270 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIA---------------RNLEGAKAAAGDLG 47 KV + G +RG GR+ A +A++G + I +L DL Sbjct: 38 KVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVKDLD 97 Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED-MVSQLHT 106 + DV +++ + + LGR++ +V AG+ DG + ++ + Sbjct: 98 RRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDI 157 Query: 107 NLLGSMLTCKAAMRT-MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 NL G T KA + + +GGSIV S+ G K Y A+K G++G RA A E Sbjct: 158 NLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVE 217 Query: 166 VARKKIRVNVVAPGFVHTDMT----------KDLKEEHLKKNIPLGR--------FGETI 207 + IRVN V P V T M DL+ P+ + + + Sbjct: 218 LGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWVDAS 277 Query: 208 EVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 ++++AV+FL S Y+TG L VD G L Sbjct: 278 DISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >3V8B-A nrPDB Length = 283 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 72/255 (28%), Positives = 120/255 (47%), Gaps = 20/255 (7%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVA 58 V + G GIGRA A +A G + + R + A ++ GG +A DV+ Sbjct: 28 SPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVS 87 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 E ++N +L G ++ +V AGIN + K + + NL G+ LT Sbjct: 88 DELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHL 147 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGN--SGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 + + Q+ GG+IV V SI G + G + Y+A+K V + LA E+ + IRVN Sbjct: 148 TVPYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNA 207 Query: 176 VAPGFVHTDMTK----------DLKEEHLKKNIPL--GRFGETIEVAHAVVFLLE--SPY 221 V PG + T+++ + E K +P+ G+ G + +VA + FL+ + + Sbjct: 208 VCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARH 267 Query: 222 ITGHVLVVDGGLQLI 236 +TG + +DGG L+ Sbjct: 268 VTGSPVWIDGGQGLL 282 >3ZV3-A nrPDB Length = 281 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 113/253 (44%), Gaps = 23/253 (9%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V + GG+ G+GRA+ +G R+AV+ ++ E + GG+ + DV D Sbjct: 7 VALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVRSLQDQ 66 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED-----MVSQLHTNLLGSMLTCKAA 118 + E G+++ L+ AGI + ED H N+ G + KA Sbjct: 67 KRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYIHAVKAC 126 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + ++ + GS+V S G N G +Y+A+K +VG R +A E+A +RVN VAP Sbjct: 127 LPALVSSR-GSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH-VRVNGVAP 184 Query: 179 GFVHTDMTKDLK-------------EEHLKKNIPLGRFGETIEVAHAVVFLL---ESPYI 222 G ++TD+ + LK +P+GR E A VF +S Sbjct: 185 GGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFATRGDSLPA 244 Query: 223 TGHVLVVDGGLQL 235 TG +L DGG+ + Sbjct: 245 TGALLNYDGGMGV 257 >1E3W-A nrPDB Length = 261 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 119/248 (47%), Gaps = 16/248 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V + GG+ G+G + A+ + +G ++ + A LGG+ + +V E +V Sbjct: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 Query: 64 QNTFEELEKHLGRVNFLVNAAGIN------RDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 Q ++ GR++ VN AGI + ED ++ NL+G+ + Sbjct: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRL 131 Query: 118 AMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A I Sbjct: 132 VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 Query: 172 RVNVVAPGFVHTDMTKDLKE---EHLKKNIPL-GRFGETIEVAHAVVFLLESPYITGHVL 227 RV +APG T + L + L +P R G+ E AH V ++E+P++ G V+ Sbjct: 192 RVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVI 251 Query: 228 VVDGGLQL 235 +DG +++ Sbjct: 252 RLDGAIRM 259 >4TRR-A nrPDB Length = 269 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 124/254 (48%), Gaps = 21/254 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 K V G + GIG+ +A +A+ G +A+ N +GA A A ++ GG + + DV Sbjct: 15 KTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMDVTN 74 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 E V +++ + G V+ LV+ AGI + D ++ G+ LT KAA+ Sbjct: 75 EEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTTKAAL 134 Query: 120 RTMIQ-QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 + M + +GG ++ +GS+ + + +S Y +K GL+G +R LAKE A+ +R +VV P Sbjct: 135 KHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSHVVCP 194 Query: 179 GFVHTDMTK----------DLKEEHLKKNIPLGR-----FGETIEVAHAVVFLLE--SPY 221 GFV T + + EE + K + LG F +VA V+FL S Sbjct: 195 GFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLSAFPSAA 254 Query: 222 ITGHVLVVDGGLQL 235 +TG +V G + Sbjct: 255 LTGQSFIVSHGWFM 268 >1CYD-A nrPDB Length = 244 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 102/237 (43%), Gaps = 13/237 (5%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V G +GIGR + + G ++ + R + A + G D+ Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG-IEPVCVDLGDWD--- 65 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 E+ +G V+ LVN A + + E NL + R MI Sbjct: 66 -ATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMIN 124 Query: 125 QQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 + GSIVNV S+V YS++KG + ++A+A E+ KIRVN V P V T Sbjct: 125 RGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLT 184 Query: 184 DMTKDLKEE-----HLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGL 233 DM K + + LK+ PL +F E +V ++++FLL S +G ++VD G Sbjct: 185 DMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAGY 241 >3U4C-A nrPDB Length = 281 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 115/256 (44%), Gaps = 26/256 (10%) Query: 1 MDK-VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH-----LAFS 54 M K V G S+GIG+A+A +A + + L + +RNL+ ++ D+ H + + Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA 80 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 D++ +H F+++E GR++ L+N EDM + + + Sbjct: 81 GDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDA 140 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSAS--KGGLVGFSRALAKEVARKKIR 172 K A M Q + G I+N+ + L G ++++ S L+ S+ ++ ++A I Sbjct: 141 IKRASSLMKQNEFGRIINI--VGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNIT 198 Query: 173 VNVVAPGFVHTD--------------MTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE 218 VN + PGF+ TD ++K EE + IP+ R G E A FL Sbjct: 199 VNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLAS 258 Query: 219 --SPYITGHVLVVDGG 232 + YITG + DGG Sbjct: 259 EEASYITGQQISADGG 274 >2FWM-X nrPDB Length = 250 Score = 194 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 103/248 (41%), Gaps = 22/248 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G +GIG A A G ++ G A DVA Sbjct: 8 KNVWVTGAGKGIGYATALAFVEAGAKVT-------GFDQAFTQEQYPFATEVMDVADAAQ 60 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 V + L R++ LVNAAGI R G + ED N+ G+ + M Sbjct: 61 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 120 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 +Q+GG+IV V S G S Y ASK L + ++ E+A +R NVV+PG Sbjct: 121 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 180 Query: 183 TDMTKDLK-------------EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 227 TDM + L E K IPLG+ E+A+ ++FL + +IT + Sbjct: 181 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 240 Query: 228 VVDGGLQL 235 VVDGG L Sbjct: 241 VVDGGSTL 248 >2AG5-A nrPDB Length = 246 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 59/228 (25%), Positives = 103/228 (45%), Gaps = 18/228 (7%) Query: 20 QLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNF 79 AR+G ++ N + G DV K+ + E+E R++ Sbjct: 24 LAFAREGAKVIATDINESKLQELEKYPGIQTRVL--DVTKKKQIDQFANEVE----RLDV 77 Query: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIV-G 138 L N AG G ++ + +D ++ N+ L KA + M+ Q+ G+I+N+ S+ Sbjct: 78 LFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASS 137 Query: 139 LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK---------DL 189 +KG + VYS +K ++G ++++A + ++ IR N V PG V T + + Sbjct: 138 VKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEE 197 Query: 190 KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 K GRF E+A V+L S Y+TG+ +++DGG L Sbjct: 198 ARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 245 >5JY1-A nrPDB Length = 274 Score = 191 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 73/245 (29%), Positives = 111/245 (45%), Gaps = 12/245 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAK 59 +V V G GIGR VA+ +G + + N + ++ GG L DV Sbjct: 15 RVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTDVTS 74 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDM-VSQLHTNLLGSMLTCKAA 118 + ++ + G ++ LVN A + +L+ KT++M L T+L + +AA Sbjct: 75 KASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAMRAA 134 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178 M +++ G IVN SI G Y+ +K G+VG +R+ A E R I VN +AP Sbjct: 135 FVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNAIAP 194 Query: 179 ---GFVHTDMTKDLKE--EHLKKNIPLGRFGETI-EVAHAVVFLLE--SPYITGHVLVVD 230 G ++ E E PLGR G+ ++ A VF S ++TG L VD Sbjct: 195 TAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVTGETLHVD 254 Query: 231 GGLQL 235 GGL L Sbjct: 255 GGLHL 259 >5O3Z-A nrPDB Length = 263 Score = 189 bits (481), Expect = 8e-49, Method: Composition-based stats. Identities = 66/258 (25%), Positives = 115/258 (44%), Gaps = 23/258 (8%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL-----GGDHLAFSC 55 M++V V GG + +G + + +A+ GY +AV N A A + G F Sbjct: 5 MEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKV 64 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 D E V+ +++ GR + LV +AG+ + + + + D L NL+G L Sbjct: 65 DATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCS 124 Query: 116 KAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 + + MI+ G I+ + S G G+ S YSA+K G VG +++LA ++A I V+ Sbjct: 125 REFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVH 184 Query: 175 VVAPG-FVHTDMTKDLK--------------EEHLKKNIPLGRFGETIEVAHAVVFLLE- 218 + G + + M + L E + +PL R + +V + ++F Sbjct: 185 SLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASD 244 Query: 219 -SPYITGHVLVVDGGLQL 235 + Y TG + V GG + Sbjct: 245 KAAYCTGQSINVTGGQVM 262 >1BDB-A nrPDB Length = 277 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 65/252 (25%), Positives = 109/252 (43%), Gaps = 23/252 (9%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + GG+ G+GRA+ +G ++AV+ ++ E D G + L DV D + Sbjct: 8 VLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRSLEDQK 67 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED-----MVSQLHTNLLGSMLTCKAAM 119 G+++ L+ AGI + E+ H N+ G + KA + Sbjct: 68 QAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHAVKACL 127 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 ++ + G+++ S G N G +Y+A+K +VG R LA E+A +RVN V G Sbjct: 128 PALVASR-GNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-VRVNGVGSG 185 Query: 180 FVHTDMTKDLK-------------EEHLKKNIPLGRFGETIEVAHAVVFLL---ESPYIT 223 +++D+ + LK +P+GR E E A VF ++ T Sbjct: 186 GINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFATRGDAAPAT 245 Query: 224 GHVLVVDGGLQL 235 G +L DGGL + Sbjct: 246 GALLNYDGGLGV 257 >5IZ4-A nrPDB Length = 271 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 70/254 (27%), Positives = 113/254 (44%), Gaps = 23/254 (9%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARN------LEGAKAAAGDLGGDHLAFSCDV 57 VC + G + GIG A A A+ G+ +A+ + +A D G L F DV Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGL---LVRTKTEDMVSQLHTNLLGSMLT 114 K+ D ++ + + R++ L+N AG R + + NL+G Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 115 CKAAMRTMIQQ----QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK 170 +AA+ + + + S+VNV S+ GL G Y+ASKG + + +LA+ +A Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLAPH- 194 Query: 171 IRVNVVAPGFVHTDMTKDLKE--------EHLKKNIPLGRFGETIEVAHAVVFL-LESPY 221 IRVN +APG V + + + + ++ PL R E+A FL +P Sbjct: 195 IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLTAHAPA 254 Query: 222 ITGHVLVVDGGLQL 235 ITG V+ + GL L Sbjct: 255 ITGQVIAAENGLLL 268 >4RGB-A nrPDB Length = 294 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 64/267 (23%), Positives = 108/267 (40%), Gaps = 34/267 (12%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAV---------------IARNLEGAKAAAGDLG 47 +V + G +RG GR+ A + A +G + LE G Sbjct: 26 RVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVEKTG 85 Query: 48 GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN 107 + L DV + +Q F+ + G ++ ++ AG+ R +E + L Sbjct: 86 QEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGLDIM 145 Query: 108 LLGSMLTCKAAMRTMIQQ-QGGSIVNVGSIVGLK----GNSGQSVYSASKGGLVGFSRAL 162 L+G T + A+ M ++ QGG+++ S++ L G G Y SK + G R+ Sbjct: 146 LIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLVRSY 205 Query: 163 AKEVARKKIRVNVVAPGFVHTDMTKDLKE------------EHLKKNIPLGRFGETIEVA 210 A +A +IRVN VAP T M + + +P E +V+ Sbjct: 206 ALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEPRDVS 265 Query: 211 HAVVFLLESPY--ITGHVLVVDGGLQL 235 +A++FL+ TG VL VD G+ + Sbjct: 266 NAILFLISDAGRSFTGSVLKVDAGMDV 292 >4EGF-A nrPDB Length = 266 Score = 179 bits (455), Expect = 8e-46, Method: Composition-based stats. Identities = 72/245 (29%), Positives = 109/245 (44%), Gaps = 12/245 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGA----KAAAGDLGGDHLAFSCDVA 58 K + G ++GIG +A+ A G RL + R++ +A G D + D+A Sbjct: 21 KRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVAIDLA 80 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + + G ++ LVN AGI+ +V T + + + NL L A Sbjct: 81 EPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLASAV 140 Query: 119 MRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 + M+ GG+I+ V S L Y SK GLV ++ LA+E+ IR N V Sbjct: 141 GKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVC 200 Query: 178 PGFVHTDMTK-----DLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVD 230 P V T+M + + K + IPLGRF EV+ AVV+L + I G + VD Sbjct: 201 PTVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVDIPVD 260 Query: 231 GGLQL 235 GG + Sbjct: 261 GGYTM 265 >4CR6-A nrPDB Length = 271 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 113/249 (45%), Gaps = 16/249 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G + GIGRA + R+G + + A + G + +CD+A Sbjct: 16 KAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG--AIPIACDLADRAA 73 Query: 63 VQNTFEELEKHLGRVNFLVNAAGI-NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + + LG ++ LV + G + D + N+ G+ LTC+A R Sbjct: 74 IDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAGARA 133 Query: 122 MIQQQGG------SIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175 M+ G I+ +GS+ + Y A+KGG+ +RA+A ++AR I VN+ Sbjct: 134 MVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGILVNM 193 Query: 176 VAPGFVH-----TDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLV 228 +APG V T ++ E + + LGR G EVA A VFL E S +ITG + Sbjct: 194 IAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAEDGSSFITGSTIT 253 Query: 229 VDGGLQLIL 237 +DGGL ++ Sbjct: 254 IDGGLSAMI 262 >2P91-A nrPDB Length = 285 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 105/250 (42%), Gaps = 18/250 (7%) Query: 3 KVCAVFGGS--RGIGRAVAQLMARKGYRLAVIARN---LEGAKAAAGDLGGDHLAFSCDV 57 K + G + R I +A+ R+G +LA + + A G D L CDV Sbjct: 22 KRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSD-LVVKCDV 80 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGSML 113 + + D++N + LE++ G ++ +V++ G ++ T E + ++ + Sbjct: 81 SLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYSLIA 140 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 + + M + + G+IV + K +V +K L R LA ++A+ R+ Sbjct: 141 LTRELLPLM-EGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHGHRI 199 Query: 174 NVVAPGFVHTDMTKDLK-----EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G V T + EH K P G+ +V VFL + ITG V Sbjct: 200 NAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARAITGEV 259 Query: 227 LVVDGGLQLI 236 + VD G ++ Sbjct: 260 VHVDNGYHIM 269 >2X9N-A nrPDB Length = 288 Score = 178 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 73/265 (27%), Positives = 117/265 (44%), Gaps = 37/265 (13%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARN-LEGAKAAAGDLGGD----HLAFSCDVAK 59 V G ++ IGRA+A + + GYR+ + N E A + A +L + + D+ Sbjct: 26 AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTN 85 Query: 60 ----EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED----------MVSQLH 105 + + GR + LVN A LV+ ED + + Sbjct: 86 SNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG 145 Query: 106 TNLLGSMLTCKAAMRTMIQQQGG----------SIVNVGSIVGLKGNSGQSVYSASKGGL 155 TN + L + Q+Q G SIVN+ + + S+Y+ K L Sbjct: 146 TNAIAPFLLT----MSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHAL 201 Query: 156 VGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKE-EHLKKNIPLGRF-GETIEVAHAV 213 VG +++ A E+A IRVN VAPG + +E + ++ +PLGR ++A AV Sbjct: 202 VGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAV 261 Query: 214 VFLL--ESPYITGHVLVVDGGLQLI 236 +FL+ + YITG ++ VDGGL L+ Sbjct: 262 IFLVSGSAQYITGSIIKVDGGLSLV 286 >4DA9-A nrPDB Length = 280 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 70/247 (28%), Positives = 118/247 (47%), Gaps = 15/247 (6%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-NLEGAKAAAGDL---GGDHLAFSCDVAK 59 V V GG RGIG +A+ +A G+ +A+ + EG +L G + D+A Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRD--GLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 Q T + + GR++ LVN AGI + K E+ + + NL G++ +A Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQA 150 Query: 118 AMRTMIQ---QQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 ++ M+ + SI+N+ S+ + + + Y SK GL FS+ LA +A I V Sbjct: 151 VLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVF 210 Query: 175 VVAPGFVHTDMTKDLKEEH----LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLV 228 V PG + +DMT + ++ +P+ R+GE ++ + V L + + TG V+ Sbjct: 211 EVRPGIIRSDMTAAVSGKYDGLIESGLVPMRRWGEPEDIGNIVAGLAGGQFGFATGSVIQ 270 Query: 229 VDGGLQL 235 DGGL + Sbjct: 271 ADGGLSI 277 >4ZJU-A nrPDB Length = 275 Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 100/247 (40%), Gaps = 17/247 (6%) Query: 6 AVFGGSR--GIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG---GDHLAFSCDVAKE 60 + G + I +AQ + R+G LA N E K + G L F CDVA + Sbjct: 20 LIAGVASKLSIAYGIAQALHREGAELAFTYPN-EKLKKRVDEFAEQFGSKLVFPCDVAVD 78 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 ++ N F EL KH V+ +V++ G DG D H S + Sbjct: 79 AEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISAYSFVAMA 138 Query: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 A + ++Q + G ++ + + +V +K L R LA + IRVN + Sbjct: 139 RAAKPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVDGIRVNAI 198 Query: 177 APGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVV 229 + G + T +K + +K PL R EV +A +FL + ITG +L V Sbjct: 199 SAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLCSPWASGITGEILYV 258 Query: 230 DGGLQLI 236 D G + Sbjct: 259 DAGFNTV 265 >3OML-A nrPDB Length = 613 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 65/227 (28%), Positives = 96/227 (42%), Gaps = 16/227 (7%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR---------NLEGAKAAAGDLGGDHLAF 53 +V V G G+GR A L A +G ++ V + A ++ Sbjct: 20 RVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEA 79 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 D D E K GRV+ LVN AGI RD LV+T +D +L GS Sbjct: 80 VADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGSFK 139 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +AA M +Q G I+ S G+ GN GQ Y+A+K GL+G + +A E AR + Sbjct: 140 CTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLC 199 Query: 174 NVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP 220 NV+ P + MT+ + + L + + +A V +L Sbjct: 200 NVIVPTA-ASRMTEGILPDILFNEL------KPKLIAPVVAYLCHES 239 >2BGM-A nrPDB Length = 278 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 65/231 (28%), Positives = 105/231 (45%), Gaps = 15/231 (6%) Query: 19 AQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL--AFSCDVAKEHDVQNTFEELEKHLGR 76 A+L R G ++ + + + ++G + CDV K+ DV+N + G+ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 77 VNFLVNAAGINRDGL--LVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVG 134 ++ + G+ ++ ED + N+ G+ L K A R MI + GSIV Sbjct: 93 LDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTA 152 Query: 135 SIVGLKGNSGQS-VYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDL---- 189 SI G S VY+A+K ++G + +L E+ IRVN V+P V + + D+ Sbjct: 153 SISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGVD 212 Query: 190 ---KEEHLKKNIPL-GRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQ 234 EE + L G +VA AV +L ES Y++G LV+DGG Sbjct: 213 SSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYT 263 >1W73-A nrPDB Length = 302 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 13/229 (5%) Query: 22 MARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVAKEHDVQNTFEELEKHLGRV 77 ++ G + + +R ++ KA A + G A CDV VQNT EL K G Sbjct: 46 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHP 105 Query: 78 NFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGG-SIVNVGSI 136 N ++N A N R + L G+ + +I+ Q G + +++ +I Sbjct: 106 NIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTI 165 Query: 137 VGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM------TKDLK 190 G+ +++K G+ S++LA E + +R NV+ PG + T Sbjct: 166 YAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTF 225 Query: 191 EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLIL 237 E+ + IP GR G E+A+ FL + +I G V+ DGG ++++ Sbjct: 226 EKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLI 274 >3PXX-A nrPDB Length = 287 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 69/281 (24%), Positives = 107/281 (38%), Gaps = 52/281 (18%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAV---------------IARNLEGAKAAAGDL 46 DKV V GG+RG GR+ A +A +G + + +R+LE A Sbjct: 10 DKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVEKT 69 Query: 47 GGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHT 106 G DV V G+++ +V AGI G + Sbjct: 70 GRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLG--AHLPVQAFADAFDV 127 Query: 107 NLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLK-----------GNSGQSVYSASKGGL 155 + +G + T AA+ + G SI+ GS+ GL G + YS +K + Sbjct: 128 DFVGVINTVHAALPYLTS--GASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQLV 185 Query: 156 VGFSRALAKEVARKKIRVNVVAPGFVHTDMT-------------------KDLKEEHLKK 196 ++ LA ++A + IR NV+ P V+TDM L + Sbjct: 186 DSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFPAMQ 245 Query: 197 NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 +P + E ++++AV FL S Y+TG VD G L Sbjct: 246 AMPTP-YVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >5TF4-A nrPDB Length = 274 Score = 174 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 60/240 (25%), Positives = 100/240 (41%), Gaps = 17/240 (7%) Query: 11 SRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSC---DVAKEHDVQNTF 67 +R I +A+ + G LA + E K L + F C DV+ + F Sbjct: 23 NRSIAWGIAKTASSAGAELAFTYQG-EAMKKRVEPLAEEVKGFVCGHCDVSDSASIDAVF 81 Query: 68 EELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 +EK G+++FLV+A G + G V + + ++ ++ K A + M Sbjct: 82 NTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSLTALTKRAEKLM- 140 Query: 124 QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 GGSI+ + K +V +K L + LA ++ K IRVN ++ G + T Sbjct: 141 -SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAISAGPIKT 199 Query: 184 DMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 + + + + N PL R EV + ++LL S +TG V VD G +I Sbjct: 200 LAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSVTGEVHHVDSGYNII 259 >2NWQ-A nrPDB Length = 272 Score = 174 bits (441), Expect = 3e-44, Method: Composition-based stats. Identities = 49/226 (21%), Positives = 92/226 (40%), Gaps = 15/226 (6%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG--DHLAFSCDVA 58 M + G + G G A A+ A G+ L + R E +A AG+L L + DV Sbjct: 20 MSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVR 79 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDG-LLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + + L + + L+N AG+ +D + + TN+ G + + + Sbjct: 80 DRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRL 139 Query: 118 AMRTMIQQQGG-SIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 + +I G SIVN+GS+ G G VY +K + FS L ++ +RV + Sbjct: 140 LLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNL 199 Query: 177 APGFVHTDMT-------KDLKEEHLKKNIPLGRFGETIEVAHAVVF 215 PG ++ + + ++ P+ + ++A + + Sbjct: 200 EPGLCESEFSLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFW 241 >4M89-A nrPDB Length = 261 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 60/249 (24%), Positives = 106/249 (42%), Gaps = 17/249 (6%) Query: 3 KVCAVFG--GSRGIGRAVAQLMARKGYRLA---VIARNLEGAKAAAGDLGGDHLAFSCDV 57 K + G R I +A+ +G LA V+ + E + A +L + L F CDV Sbjct: 7 KKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSE-LVFRCDV 65 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGSML 113 A + ++ F +L KH ++ LV++ G G + + + + + H S+ Sbjct: 66 ASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAYSLP 125 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A R M++ + +IV + + ++ +V +K L R A + ++ IR Sbjct: 126 ALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEGIRC 185 Query: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G + T + + H+ + PL R EV + FLL S ITG + Sbjct: 186 NGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDLSSGITGEI 245 Query: 227 LVVDGGLQL 235 VDGG + Sbjct: 246 TYVDGGYSI 254 >2YW9-A nrPDB Length = 261 Score = 173 bits (439), Expect = 7e-44, Method: Composition-based stats. Identities = 63/250 (25%), Positives = 111/250 (44%), Gaps = 19/250 (7%) Query: 3 KVCAVFGGS--RGIGRAVAQLMARKGYRLAVIA---RNLEGAKAAAGDLGGDHLAFSCDV 57 K V G + R +G A+A + G +A+ R A+ A LGG L F DV Sbjct: 9 KKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGG-ALLFRADV 67 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSML 113 ++ ++ F +++ G +++LV+A +G + T+ +D + L + + Sbjct: 68 TQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYSLVA 127 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 + A + ++GG IV + K +V + +K L R LA E+ K +RV Sbjct: 128 VARRAEPLL--REGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVRV 185 Query: 174 NVVAPGFVHTDMTKDLK-----EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G V T + + + + + PL R EV + +FLL + ITG V Sbjct: 186 NAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASGITGEV 245 Query: 227 LVVDGGLQLI 236 + VD G ++ Sbjct: 246 VYVDAGYHIM 255 >4NR0-A nrPDB Length = 273 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 19/250 (7%) Query: 3 KVCAVFGGSR--GIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG-----GDHLAFSC 55 K + G + I +A M R+G LA +N + + + L F C Sbjct: 7 KRALIVGVASKLSIASGIAAAMHREGAELAFTYQN-DKLRGRVEEFASGWGSRPELCFPC 65 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGS 111 DVA + ++ F L KH ++ +V++ G DG T + H S Sbjct: 66 DVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISAYS 125 Query: 112 MLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 + A R M++ + GS++ + + + +V +K L R LA + + Sbjct: 126 FIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGAEGT 185 Query: 172 RVNVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITG 224 RVN V+ G + T +K ++ PL R EV +A FL + I+G Sbjct: 186 RVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLASGISG 245 Query: 225 HVLVVDGGLQ 234 +L VDGG Sbjct: 246 EILYVDGGFN 255 >3GRK-A nrPDB Length = 293 Score = 169 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 59/240 (24%), Positives = 99/240 (41%), Gaps = 17/240 (7%) Query: 11 SRGIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67 +R I +A+ G LA + + A +LG +A CDVA + F Sbjct: 42 NRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGA-FVAGHCDVADAASIDAVF 100 Query: 68 EELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 E LEK G+++FLV+A G + G + T + + + ++ + A + M Sbjct: 101 ETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYSLTAVSRRAEKLM- 159 Query: 124 QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 GGSI+ + K +V +K L + LA ++ + IRVN ++ G + T Sbjct: 160 -ADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIRVNAISAGPIKT 218 Query: 184 DMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 + + + + N PL R EV ++ L S +TG V D G +I Sbjct: 219 LAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLSRSVTGEVHHADSGYHVI 278 >4DRY-A nrPDB Length = 281 Score = 169 bits (429), Expect = 8e-43, Method: Composition-based stats. Identities = 59/212 (27%), Positives = 91/212 (42%), Gaps = 9/212 (4%) Query: 18 VAQLMARKGYRLAVIARNLEGAKAAAGDLGGD----HLAFSCDVAKEHDVQNTFEELEKH 73 +AQ ++ +GY + + R + AAAG++GG A CDV V F + Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAE 108 Query: 74 LGRVNFLVNAAGIN-RDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQ--QGGSI 130 R++ LVN AG N L E + NL G+ L + A R M Q +GG I Sbjct: 109 FARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTPRGGRI 168 Query: 131 VNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLK 190 +N GSI + Y+A+K + G +++ A + I + G TDMT + Sbjct: 169 INNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATDMTARMS 228 Query: 191 EEHLKKN--IPLGRFGETIEVAHAVVFLLESP 220 L+ N + +A AVV++ P Sbjct: 229 TGVLQANGEVAAEPTIPIEHIAEAVVYMASLP 260 >3K2E-A nrPDB Length = 296 Score = 169 bits (429), Expect = 9e-43, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 103/250 (41%), Gaps = 19/250 (7%) Query: 3 KVCAVFGGS--RGIGRAVAQLMARKGYRLAVIARNL---EGAKAAAGDLGGDHLAFSCDV 57 K + G + + + +A+ + +G +A+ + + A LG L CDV Sbjct: 31 KKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVK-LTVPCDV 89 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGSML 113 + V N F+ L + G ++F+V+A + G V T + ++ +H + Sbjct: 90 SDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCYSFTY 149 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A M GGSI+ + K +V K L + LA ++ +++IRV Sbjct: 150 IASKAEPLMT--NGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQIRV 207 Query: 174 NVVAPGFVHTDMTKDLKEEHL-----KKNIPLGRFGETIEVAHAVVFLLES--PYITGHV 226 N ++ G V T + + + H K N PL R +V A ++LL TG Sbjct: 208 NAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSDLGRGTTGET 267 Query: 227 LVVDGGLQLI 236 + VD G ++ Sbjct: 268 VHVDCGYHVV 277 >5KOI-A nrPDB Length = 293 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 60/238 (25%), Positives = 101/238 (42%), Gaps = 18/238 (7%) Query: 14 IGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEEL 70 + +A+ +A +G LA + K A +G D + CDV V FEE+ Sbjct: 42 LAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFV-LPCDVEDIATVDAVFEEI 100 Query: 71 EKHLGRVNFLVNAAGINRDGLL-----VRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQ 125 EK G ++FLV+A G + L T E+ + + + A + M + Sbjct: 101 EKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYSFTEVAQRAEKLM--K 158 Query: 126 QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM 185 GGSI+ + + +V +K L R LA + + IRVN ++ G V T Sbjct: 159 DGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVRTLA 218 Query: 186 TKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 + + + ++N PL R + +V + V+LL S +TG + VD G ++ Sbjct: 219 GAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVTGEIHFVDSGYNIV 276 >3PPI-A nrPDB Length = 281 Score = 167 bits (423), Expect = 4e-42, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 111/245 (45%), Gaps = 21/245 (8%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V GG+ G+G A + + G + + E KA A +LG S +V E V Sbjct: 33 AIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSVL 92 Query: 65 NTFEELEKHLGRVNFLVNAAG--------INRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 E LGR+ + V A G + RDG + L G+ + Sbjct: 93 AAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMG--GFTKTIDLYLNGTYNVAR 149 Query: 117 ------AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK 170 AA + G++V SI G +G GQ+ Y+A+K G++G + A A++++ Sbjct: 150 LVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAARDLSSAG 209 Query: 171 IRVNVVAPGFVHTDMTKDLKEEHLKK---NIPL-GRFGETIEVAHAVVFLLESPYITGHV 226 IRVN +APG + T + + + EE L K NIP R G E A A FLL + YI G V Sbjct: 210 IRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFADAAAFLLTNGYINGEV 269 Query: 227 LVVDG 231 + +DG Sbjct: 270 MRLDG 274 >3RKU-A nrPDB Length = 287 Score = 166 bits (422), Expect = 5e-42, Method: Composition-based stats. Identities = 60/229 (26%), Positives = 96/229 (41%), Gaps = 20/229 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARK---GYRLAVIARNLEGAKAAAGDL-----GGDHLAFS 54 K + G S GIG+A A +L + AR LE + + Sbjct: 34 KTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQ 93 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLV-RTKTEDMVSQLHTNLLGSML 113 D+ + ++ E L + ++ LVN AG V + TED+ TN+ + Sbjct: 94 LDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALIN 153 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +A + + G IVN+GSI G S+Y ASK + F+ +L KE+ KIRV Sbjct: 154 ITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRV 213 Query: 174 NVVAPGFVHTDMT-------KDLKEEHLKKNIPLGRFGETIEVAHAVVF 215 ++APG V T+ + ++ + K PL +VA +V+ Sbjct: 214 ILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPL----MADDVADLIVY 258 >1P33-A nrPDB Length = 289 Score = 166 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 67/279 (24%), Positives = 113/279 (40%), Gaps = 48/279 (17%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIA-RNLEGAKAAAGDLGGD----HLAFSCDVA 58 V V G ++ +G ++A+ + +GY + + R+ A A L + D++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 59 KEHD-----------------VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED-- 99 + H GR + LVN A L+R + Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 100 ------------MVSQLHTNLLGSMLTCKA----AMRTMIQQQGGS--IVNVGSIVGLKG 141 +N + KA T +Q+G S IVN+ + + Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 142 NSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF--VHTDMTKDLKEEHLKKNIP 199 G ++Y+ +K L G +R+ A E+A +IRVN V+PG + DM ++E++ ++ +P Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLPDDMPFSVQEDY-RRKVP 247 Query: 200 L-GRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 L R EV+ V+FL + YITG + VDGG L Sbjct: 248 LYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >5YCX-A nrPDB Length = 266 Score = 166 bits (420), Expect = 9e-42, Method: Composition-based stats. Identities = 53/251 (21%), Positives = 102/251 (40%), Gaps = 19/251 (7%) Query: 3 KVCAVFGGS--RGIGRAVAQLMARKGYRLAVIA---RNLEGAKAAAGDL-GGDHLAFSCD 56 K V G + R I +A+ + G +L R + A L G + L CD Sbjct: 9 KTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVLPCD 68 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSM 112 V + ++ FE +++ +G ++ + + G V T + + + + Sbjct: 69 VTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISAFSLT 128 Query: 113 LTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIR 172 + A + M + GG+I+ + + G + +V +K L + LA ++ + IR Sbjct: 129 AVAREAKKVMTE--GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQHGIR 186 Query: 173 VNVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGH 225 VN ++ G + T K + + +++ PL R EV VFL + +TG Sbjct: 187 VNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLARGVTGE 246 Query: 226 VLVVDGGLQLI 236 + VD G ++ Sbjct: 247 NIHVDSGYHIL 257 >3OIG-A nrPDB Length = 266 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 56/251 (22%), Positives = 102/251 (40%), Gaps = 21/251 (8%) Query: 3 KVCAVFGGS--RGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG-----DHLAFSC 55 + V G + R I +A+ + G RL E + + +L G D + C Sbjct: 8 RNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAG-ERLEKSVHELAGTLDRNDSIILPC 66 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGS 111 DV + +++ F +++ +G ++ + + G + T + + + + Sbjct: 67 DVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSL 126 Query: 112 MLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 KAA M + GGSIV + + G +V +K L + LA ++ ++ I Sbjct: 127 TAVVKAARPMMTE--GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENI 184 Query: 172 RVNVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITG 224 RVN ++ G + T K + + + +++ PL R EV FL S ITG Sbjct: 185 RVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITG 244 Query: 225 HVLVVDGGLQL 235 L VD G + Sbjct: 245 ENLHVDSGFHI 255 >1A27-A nrPDB Length = 289 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 26/216 (12%) Query: 4 VCAVFGGSRGIGRAVAQLMARK---GYRLAVIARNL-------EGAKAAAGDLGGDHLAF 53 V + G S GIG +A +A +++ R+L E A+A A G Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS-LETL 62 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 DV V E + + GRV+ LV AG+ G L + + S L N++G++ Sbjct: 63 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 120 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +A + M ++ G ++ GS+ GL G VY ASK L G +LA + + + Sbjct: 121 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 174 NVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEV 209 +++ G VHT + + G EV Sbjct: 181 SLIECGPVHTAFMEKV-------------LGSPEEV 203 >4GKB-A nrPDB Length = 258 Score = 165 bits (419), Expect = 1e-41, Method: Composition-based stats. Identities = 69/247 (27%), Positives = 107/247 (43%), Gaps = 16/247 (6%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK--AAAGDLGGDHLAFSCDVAK 59 DKV V GG+ GIG A++ +A + V AR+ A ++ Sbjct: 7 DKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVELQD 66 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + ++ + GR++ LVN AG+N DG+ + + V+ L NL+ + Sbjct: 67 DAQCRDAVAQTIATFGRLDGLVNNAGVN-DGIGLDAGRDAFVASLERNLIHYYAMAHYCV 125 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 + + G+IVN+ S + G S Y ASKG + +R A + +RVN V P Sbjct: 126 PHLKATR-GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPA 184 Query: 180 FVHTDMTK---------DLKEEHLKKNIPLG-RFGETIEVAHAVVFLLE--SPYITGHVL 227 V T + + + K + +PLG RF E+A VFLL + + TG L Sbjct: 185 EVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTGEWL 244 Query: 228 VVDGGLQ 234 VDGG Sbjct: 245 FVDGGYT 251 >2QHX-A nrPDB Length = 328 Score = 165 bits (419), Expect = 1e-41, Method: Composition-based stats. Identities = 67/279 (24%), Positives = 107/279 (38%), Gaps = 48/279 (17%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIA-RNLEGAKAAAGDLGGD----HLAFSCDVA 58 V V G ++ +GR++A+ + +GY + + R+ A A + L + D++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 59 KEHD-----------------VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMV 101 H GR + LVN A L+R + Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 102 --------------SQLHTNLLGSMLTCKAAM------RTMIQQQGGSIVNVGSIVGLKG 141 +N + KA + SI+N+ + + Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 142 NSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF--VHTDMTKDLKEEHLKKNIP 199 G ++Y+ +KG L G +R+ A E+A +IRVN V PG + DM + E H + +P Sbjct: 228 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGH-RSKVP 286 Query: 200 L-GRFGETIEVAHAVVFLLES--PYITGHVLVVDGGLQL 235 L R EV+ V+FL S YITG + VDGG L Sbjct: 287 LYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >5I9N-A nrPDB Length = 276 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 57/251 (22%), Positives = 98/251 (39%), Gaps = 18/251 (7%) Query: 3 KVCAVFG--GSRGIGRAVAQLMARKGYRLAVI---ARNLEGAKAAAGDLGGDHLAFSCDV 57 K + G +R I +A+ R+G LA R + A + G + L F CDV Sbjct: 7 KRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE-LVFPCDV 65 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSML 113 A + + F L+ H ++ LV++ G G + T + H S Sbjct: 66 ADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFP 125 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A M+ S++ + + + + +K L R LA + K +RV Sbjct: 126 ALAKAALPMLSDD-ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRV 184 Query: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G + T +K + ++ N PL R +V +A FLL + +T V Sbjct: 185 NAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEV 244 Query: 227 LVVDGGLQLIL 237 + VD G ++ Sbjct: 245 MHVDSGFNAVV 255 >2BFA-A nrPDB Length = 288 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 67/279 (24%), Positives = 107/279 (38%), Gaps = 48/279 (17%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIA-RNLEGAKAAAGDLGGD----HLAFSCDVA 58 V V G ++ +GR++A+ + +GY + + R+ A A + L + D++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 59 KEHD-----------------VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMV 101 H GR + LVN A L+R + Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 102 --------------SQLHTNLLGSMLTCKAAM------RTMIQQQGGSIVNVGSIVGLKG 141 +N + KA + SI+N+ + + Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 142 NSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF--VHTDMTKDLKEEHLKKNIP 199 G ++Y+ +KG L G +R+ A E+A +IRVN V PG + DM + E H + +P Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGH-RSKVP 246 Query: 200 L-GRFGETIEVAHAVVFLLES--PYITGHVLVVDGGLQL 235 L R EV+ V+FL S YITG + VDGG L Sbjct: 247 LYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >6CGE-A nrPDB Length = 328 Score = 164 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 26/216 (12%) Query: 4 VCAVFGGSRGIGRAVAQLMARK---GYRLAVIARNL-------EGAKAAAGDLGGDHLAF 53 V + G S GIG +A +A +++ R+L E A+A A G Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS-LETL 63 Query: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113 DV V E + + GRV+ LV AG+ G L + + S L N++G++ Sbjct: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 +A + M ++ G ++ GS+ GL G VY ASK L G +LA + + + Sbjct: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 Query: 174 NVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEV 209 +++ G VHT + + G EV Sbjct: 182 SLIECGPVHTAFMEKV-------------LGSPEEV 204 >5CFZ-A nrPDB Length = 305 Score = 163 bits (414), Expect = 6e-41, Method: Composition-based stats. Identities = 61/249 (24%), Positives = 104/249 (41%), Gaps = 18/249 (7%) Query: 3 KVCAVFGGSR--GIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDV 57 K V G + I +AQ M R+G LA +N + + A LG D + CDV Sbjct: 50 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQCDV 108 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSML 113 A++ + F EL K + + V++ G DG V T + H S + Sbjct: 109 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 168 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A R+M+ G +++ + + + +V +K L R +A + + +RV Sbjct: 169 AMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV 227 Query: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G + T +K+ H + P+ R +V ++ FL S I+G V Sbjct: 228 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEV 287 Query: 227 LVVDGGLQL 235 + VDGG + Sbjct: 288 VHVDGGFSI 296 >4JQC-A nrPDB Length = 282 Score = 161 bits (408), Expect = 2e-40, Method: Composition-based stats. Identities = 61/249 (24%), Positives = 104/249 (41%), Gaps = 18/249 (7%) Query: 3 KVCAVFGGSR--GIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDV 57 K V G + I +AQ M R+G LA +N + + A LG D + CDV Sbjct: 27 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQCDV 85 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSML 113 A++ + F EL K + + V++ G DG V T + H S + Sbjct: 86 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 145 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A R+M+ G +++ + + + +V +K L R +A + + +RV Sbjct: 146 AMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV 204 Query: 174 NVVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G + T +K+ H + P+ R +V ++ FL S I+G V Sbjct: 205 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEV 264 Query: 227 LVVDGGLQL 235 + VDGG + Sbjct: 265 VHVDGGFSI 273 >4ALL-A nrPDB Length = 277 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 55/252 (21%), Positives = 102/252 (40%), Gaps = 19/252 (7%) Query: 2 DKVCAVFGGS--RGIGRAVAQLMARKGYRLAVIAR---NLEGAKAAAGDLGG-DHLAFSC 55 +K + G + R I VA+++ + G +L R + + + L + + Sbjct: 27 NKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQI 86 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGS 111 DV + +V N FE++ K +G ++ + ++ G T E + + Sbjct: 87 DVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSL 146 Query: 112 MLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 + A + M +GGSIV + G +V +K L + LA ++ I Sbjct: 147 TIVAHEAKKLM--PEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNI 204 Query: 172 RVNVVAPGFVHTDMTKDLK-----EEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITG 224 RVN ++ G + T K + + +++ PL R + +EV +LL S +TG Sbjct: 205 RVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTG 264 Query: 225 HVLVVDGGLQLI 236 + VD G I Sbjct: 265 ENIHVDSGFHAI 276 >3E9N-A nrPDB Length = 245 Score = 157 bits (399), Expect = 2e-39, Method: Composition-based stats. Identities = 59/228 (25%), Positives = 108/228 (47%), Gaps = 7/228 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K+ V G + G+G + + ++R + + + RN E A A G + D+ KE Sbjct: 6 KIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEGVE--PIESDIVKEVL 62 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + ++L K+L V+ LV+AA + RD + + + L N++ + + + Sbjct: 63 EEGGVDKL-KNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLPAL 121 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 G ++ + S G + G ++Y+ASK L G + A KE A IRV+ V+PG + Sbjct: 122 RAA-SGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGPTN 180 Query: 183 TDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVD 230 T M + L + P + E E+A+A+ F++++ T + VD Sbjct: 181 TPMLQGLMDSQGTNFRP-EIYIEPKEIANAIRFVIDAGETT-QITNVD 226 >4HBG-A nrPDB Length = 286 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 105/265 (39%), Gaps = 52/265 (19%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF----SCDVA- 58 V V G +RGIG+A+ Q + +KG ++ E + A D G C +A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 59 ---------------------KEHDVQNTFEELEKHLGR---------VNFLVNAAGINR 88 ++ + L + VN L+N AG+ + Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 89 DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQG-----------GSIVNVGSI- 136 + L VRT + ++ N + + ++ M++ Q +IVN+ SI Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 137 -VGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH-TDMTKDLK---E 191 G G SVYSASK L F+ LA E+ + IR ++PG V TDM ++L + Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 Query: 192 EHLKKNIPLGRFGETIEVAHAVVFL 216 E L++ I E+A V L Sbjct: 246 EMLERTIGASGTSAPAEIAEEVWSL 270 >4J3F-A nrPDB Length = 280 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 52/249 (20%), Positives = 96/249 (38%), Gaps = 16/249 (6%) Query: 3 KVCAVFG--GSRGIGRAVAQLMARKGYRLAVIARNL--EGAKAAAGDLGGDHLAFSCDVA 58 K + G ++ I +A+ M R+G LA + + + CDV Sbjct: 27 KKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEF-NPAAVLPCDVI 85 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSMLT 114 + ++++ F EL K ++ +V++ +G + T + S H S Sbjct: 86 SDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDISAYSFAA 145 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVN 174 R+M++ + S+V + I K + +K L R A + I+VN Sbjct: 146 LAKEGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGEDGIKVN 205 Query: 175 VVAPGFVHTDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVL 227 V+ G + T + ++ PL + + +EV + V FL + ITG V+ Sbjct: 206 AVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAFLCSDMATGITGEVV 265 Query: 228 VVDGGLQLI 236 VD G + Sbjct: 266 HVDAGYHCV 274 >2HRB-A nrPDB Length = 274 Score = 153 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 54/233 (23%), Positives = 83/233 (35%), Gaps = 51/233 (21%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHL---AFSCDV 57 +V V G +RGIG A+A+ + R+ + + AR++ +AA L + L D+ Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDI 61 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++ + L K G +N LVN A + L TN + C Sbjct: 62 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 121 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSG--------------------------------- 144 + M + G +VN+ S+ L+ Sbjct: 122 LLPIM--KPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNE 179 Query: 145 --------QSVYSASKGGLVGFSRALAKEVARK----KIRVNVVAPGFVHTDM 185 S Y SK G+ SR LA+ + K +I VN PG V TDM Sbjct: 180 VHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDM 232 >5ILO-A nrPDB Length = 271 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 63/201 (31%), Positives = 95/201 (47%), Gaps = 17/201 (8%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGY-RLAVIARN---LEGAKAAAGDLGGDHLAFSCDVA 58 K V GG+ GIG V++ + G ++A+I E K A + DVA Sbjct: 16 KNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVA 75 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + V+ T+EE+ K G ++ +VN AGI D D+ L NL G + + +A Sbjct: 76 NKKGVEATYEEIAKTFGNIDIVVNVAGIFNDK--------DVQRTLLVNLGGIINSTLSA 127 Query: 119 MRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE--VARKKIRV 173 + M + GG +VN+ S+VGL VY A+K G++ F+R LA E R I+ Sbjct: 128 LPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKF 187 Query: 174 NVVAPGFVHTDMTKDLKEEHL 194 V PG TDM + E+ + Sbjct: 188 VTVCPGATMTDMFTNFTEKII 208 >3KZV-A nrPDB Length = 254 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 46/194 (23%), Positives = 79/194 (40%), Gaps = 6/194 (3%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAV--IARNLEGAKAAAGDLGGDHLAFSCDVA 58 M KV V G SRGIG+++ ++ V +AR+ K G D+ Sbjct: 1 MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDIT 60 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGL-LVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++ ++ K G+++ LV AG+ + N + Sbjct: 61 EDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGI 120 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 A+ + ++ G++V V S S Y +SK L F+ LA E ++++ VA Sbjct: 121 ALPEL-KKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVA 177 Query: 178 PGFVHTDMTKDLKE 191 PG V TDM +++E Sbjct: 178 PGIVDTDMQVNIRE 191 >3UCF-A nrPDB Length = 223 Score = 147 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 63/240 (26%), Positives = 108/240 (45%), Gaps = 33/240 (13%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V V GG+ GIG +A+ + + + V +R D++ E V Sbjct: 8 VYVVLGGTSGIGAELAKQLESEHTIVHVASRQT-----------------GLDISDEKSV 50 Query: 64 QNTFEELEKHLGRVNFLVNAAG-INRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + FE + G + L+ AG G +V + T G++L K R + Sbjct: 51 YHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGARYL 106 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 182 +QGGSI ++ K + V +A + ++ LAKE+A IRVN ++PG Sbjct: 107 --KQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAISPGLTK 162 Query: 183 TDMTKDL-------KEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQL 235 T+ K + + + ++P+G+ GE ++A A +F +++ Y+TG V+ VDGG L Sbjct: 163 TEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAYLFAIQNSYMTGTVIDVDGGALL 222 >1N5D-A nrPDB Length = 288 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 55/258 (21%), Positives = 93/258 (36%), Gaps = 53/258 (20%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGY-RLAVIARNLEGAKAAAGDLGGDHL---AFSCDV 57 +V V G ++GIG A+ + + R+ + + AR++ +AA L + L D+ Sbjct: 4 TRVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDI 63 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++ + L K G ++ LVN A I + TN +G+ C Sbjct: 64 IDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRNVCTE 123 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKG------------------------------------ 141 + +I+ Q G +VNV S G++ Sbjct: 124 LLP-LIKPQ-GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTKNG 181 Query: 142 -----NSGQSVYSASKGGLVGFSRALAKEV----ARKKIRVNVVAPGFVHTDM--TKDLK 190 S Y +K G+ SR A+++ A KI +N PG+V TDM K K Sbjct: 182 VHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDMGGPKAPK 241 Query: 191 EEHLKKNIPLGRFGETIE 208 + P+ + Sbjct: 242 SPEVGAETPVYLALLPSD 259 >4NK4-A nrPDB Length = 301 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 45/250 (18%), Positives = 100/250 (40%), Gaps = 19/250 (7%) Query: 3 KVCAVFGGSR--GIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDV 57 K + G + I +A+++ G +LA + K A + D + C+V Sbjct: 42 KRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVDSDFM-IPCNV 100 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRD----GLLVRTKTEDMVSQLHTNLLGSML 113 + FE +++ ++F+V++ + G T ++ + + + Sbjct: 101 EDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVSCFSFTE 160 Query: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 + A + M GG+++ + ++ + + +K L ++ LA + IR+ Sbjct: 161 IVRRAAQLM--PHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNIRI 218 Query: 174 NVVAPGFVHTDMTKDLKEEH-----LKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G V T + K+N PL R ++ ++ ++LL S +TG + Sbjct: 219 NAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNGVTGEI 278 Query: 227 LVVDGGLQLI 236 VD G ++ Sbjct: 279 HYVDCGYNIV 288 >3BHI-A nrPDB Length = 276 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 57/263 (21%), Positives = 94/263 (35%), Gaps = 63/263 (23%) Query: 4 VCAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHL---AFSCDVAK 59 V V GG++GIG A+ + + R + + AR++ +AA L + L D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 ++ + L K G ++ LVN AGI + TN G+ C + Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELL 125 Query: 120 RTMIQQQGGSIVNVGSIVGLKG-------------------------------------- 141 +I+ Q G +VNV SI+ ++ Sbjct: 126 P-LIKPQ-GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 183 Query: 142 ---NSGQSVYSASKGGLVGFSRALAKEVARK----KIRVNVVAPGFVHTDMTKDLKEEHL 194 S Y +K G+ SR A++++ + KI +N PG+V TDM + Sbjct: 184 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKS- 242 Query: 195 KKNIPLGRFGETIEVAHAVVFLL 217 E A V+L Sbjct: 243 -----------PEEGAETPVYLA 254 >2PD3-A nrPDB Length = 275 Score = 144 bits (363), Expect = 5e-35, Method: Composition-based stats. Identities = 48/240 (20%), Positives = 102/240 (42%), Gaps = 17/240 (7%) Query: 11 SRGIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67 ++ I +AQ +G LA N + A +L ++ + DV+KE ++ + Sbjct: 17 NKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYV-YELDVSKEEHFKSLY 75 Query: 68 EELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 ++K LG ++F+V++ +G L+ T + + ++ + + Sbjct: 76 NSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSLIELTNTLKPLL- 134 Query: 124 QQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHT 183 G S++ + + K + +V +K L R LA ++ + IRVN ++ G + T Sbjct: 135 -NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIRVNALSAGPIRT 193 Query: 184 DMTKDLKEEHL-----KKNIPLGRFGETIEVAHAVVF--LLESPYITGHVLVVDGGLQLI 236 + + + + + N PL + EV +A ++ S ++G V VD G ++ Sbjct: 194 LASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGVSGEVHFVDAGYHVM 253 >5PGZ-A nrPDB Length = 276 Score = 139 bits (352), Expect = 7e-34, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 79/188 (42%), Gaps = 7/188 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG---DLGG-DHLAFSCDVA 58 K V G S+GIGR +A +++ G + + AR+ EG + +LG + + Sbjct: 19 KKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTME 78 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + + K +G ++ L+ L + + N L ++ AA Sbjct: 79 DMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAA 138 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV--V 176 + M++Q GSI + S+ G + YSASK L GF + E+ K+ V++ Sbjct: 139 LP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSITLC 197 Query: 177 APGFVHTD 184 G + T+ Sbjct: 198 VLGLIDTE 205 >3DWF-A nrPDB Length = 276 Score = 137 bits (345), Expect = 5e-33, Method: Composition-based stats. Identities = 46/188 (24%), Positives = 77/188 (40%), Gaps = 7/188 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG---DLG-GDHLAFSCDVA 58 K V G S+GIGR +A +A+ G + V AR+ E + +LG + + Sbjct: 12 KKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSME 71 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + E +G ++ L+ + + +++ + N ++ AA Sbjct: 72 DMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAA 131 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV--V 176 M M+ Q GSI V S+ G + YSASK L GF L E K+ V++ Sbjct: 132 MP-MLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSITLC 190 Query: 177 APGFVHTD 184 G + T+ Sbjct: 191 ILGLIDTE 198 >3U9L-A nrPDB Length = 324 Score = 134 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 54/229 (23%), Positives = 96/229 (41%), Gaps = 17/229 (7%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLA-----VIARNLEGAKAAAG---DLGGDHLAFS 54 K+ + G S G GR A+ +A G+R+ ++ RN +A AG D D Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLE 65 Query: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 DV + V +++ GR++ L++ AG G E N+L + Sbjct: 66 LDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVLSTQRV 125 Query: 115 CKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ-SVYSASKGGLVGFSRALAKEVARKKIRV 173 +AA+ M +Q+ G ++ + S G + Y A+K + + A+E++R I Sbjct: 126 NRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRWGIET 185 Query: 174 NVVAPG--------FVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVV 214 +++ PG F H+ + D + + P GE I+ A A + Sbjct: 186 SIIVPGAFTSGTNHFAHSGVPDDHARQAEYEAGPNAGLGEEIKKAFAAI 234 >2DKN-A nrPDB Length = 255 Score = 132 bits (334), Expect = 9e-32, Method: Composition-based stats. Identities = 66/268 (24%), Positives = 104/268 (38%), Gaps = 54/268 (20%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V A+ G + GIG A+ +L+AR G+ + I R +A GG A + Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGRETAVAA-------- 54 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 L++ G ++ LV AG+ + + N G + Sbjct: 55 -----VLDRCGGVLDGLVCCAGVG-------VTAANSGLVVAVNYFGVSALLDGLAEALS 102 Query: 124 QQQGGSIVNVGSIVGLKGNSG--------------------------QSVYSASKGGLVG 157 + Q + V VGSI + + Y+ SK + Sbjct: 103 RGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVTC 162 Query: 158 FSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKN------IPLGRFGETIEVAH 211 +R + A + +R+NVVAPG V T + + K + PLGR E EVA Sbjct: 163 LARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEPREVAE 222 Query: 212 AVVFLL--ESPYITGHVLVVDGGLQLIL 237 A+ FLL ++ +I G VL VDGG+ ++ Sbjct: 223 AIAFLLGPQASFIHGSVLFVDGGMDALM 250 >4Z3K-A nrPDB Length = 275 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 54/213 (25%), Positives = 91/213 (42%), Gaps = 21/213 (9%) Query: 4 VCAVFGGSRGIGRAVAQLMARK---GYRLAVIARNLEGAKAAAGDLGGD-----HLAFSC 55 VC + G SRG GR +A L+A G L + ARN E + +LG + + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 56 DVAKEHDVQNTFEELEKH-----LGRVNFLVNAAGINRD---GLLVRTKTEDMVSQLHTN 107 D+ E +Q L + L R+ L+N AG D G + + + + + N Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 141 Query: 108 LLGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 L + + ++ G ++VN+ S+ L+ G ++Y A K + LA E Sbjct: 142 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 201 Query: 166 VARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNI 198 +RV APG + TDM + +E + ++ Sbjct: 202 --EPNVRVLNYAPGPLDTDMQQLARETSVDPDM 232 >4HWK-A nrPDB Length = 288 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 54/213 (25%), Positives = 91/213 (42%), Gaps = 21/213 (9%) Query: 4 VCAVFGGSRGIGRAVAQLMARK---GYRLAVIARNLEGAKAAAGDLGGD-----HLAFSC 55 VC + G SRG GR +A L+A G L + ARN E + +LG + + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 56 DVAKEHDVQNTFEELEKH-----LGRVNFLVNAAGINRD---GLLVRTKTEDMVSQLHTN 107 D+ E +Q L + L R+ L+N AG D G + + + + + N Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 108 LLGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 L + + ++ G ++VN+ S+ L+ G ++Y A K + LA E Sbjct: 155 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 214 Query: 166 VARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNI 198 +RV APG + TDM + +E + ++ Sbjct: 215 --EPNVRVLNYAPGPLDTDMQQLARETSVDPDM 245 >5L51-A nrPDB Length = 324 Score = 127 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 51/284 (17%), Positives = 88/284 (30%), Gaps = 89/284 (31%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNL----EGAKAAAGDLGGD----HLAFSCD 56 V G ++GIG + + +A KG + + +R+ E + +LG + ++ D Sbjct: 18 AVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQLD 77 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVR---------------------- 94 VA V + ++ G ++ LVN AG+N + Sbjct: 78 VADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSGAAKT 137 Query: 95 ------------TKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGN 142 E + TN GS +A + + Q IVNV S + Sbjct: 138 EPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLSSLVF 197 Query: 143 -------------------------------------------SGQSVYSASKGGLVGFS 159 S Y SK L ++ Sbjct: 198 QTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAALNAYT 257 Query: 160 RALAKEVARKKIRVNVVAPGFVHTDMTKDLKE--EHLKKNIPLG 201 R +AK+ +I N V PG+ TD++ + + P+ Sbjct: 258 RIIAKKYPSFRI--NAVCPGYTKTDLSYGHGQFTDAEAAEAPVK 299 >1OAA-A nrPDB Length = 259 Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats. Identities = 53/206 (25%), Positives = 80/206 (38%), Gaps = 21/206 (10%) Query: 4 VCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNLEGAKAAAGDLGGDHLAFS-----C 55 VC + G SRG GRA+A +AR G + V AR+ + +LG Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 56 DVAKEHDVQNTFEELEKH-----LGRVNFLVNAA---GINRDGLLVRTKTEDMVSQLHTN 107 D+ E VQ + + L R+ L+N A G G L ++ + N Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 108 LLGSMLTCKAAMRTMIQQQGGS--IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 165 L + + G S +VN+ S+ L+ G +Y A K + LA E Sbjct: 127 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 166 VARKKIRVNVVAPGFVHTDMTKDLKE 191 +RV APG + DM + +E Sbjct: 187 --EPSVRVLSYAPGPLDNDMQQLARE 210 >1SNY-A nrPDB Length = 267 Score = 123 bits (309), Expect = 7e-29, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 86/204 (42%), Gaps = 24/204 (11%) Query: 5 CAVFGGSRGIGRAVAQLMA---RKGYRLAVIARNLEGAKAAAGDLGGDH---LAFSCDVA 58 + G +RG+G + + + + L RN E AK DL +H D+ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKEL-EDLAKNHSNIHILEIDLR 82 Query: 59 KEHDVQNTFEEL--EKHLGRVNFLVNAAGINRD-GLLVRTKTEDMVSQLHTNLLGSMLTC 115 ++ +N L N AGI + ++++++ L TN + ++ Sbjct: 83 NFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLA 142 Query: 116 KAAMRTMIQQ-----------QGGSIVNVGSIVG-LKGN--SGQSVYSASKGGLVGFSRA 161 KA + + + +I+N+ SI+G ++GN G Y SK L +++ Sbjct: 143 KACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKS 202 Query: 162 LAKEVARKKIRVNVVAPGFVHTDM 185 L+ ++ ++I + PG+V TDM Sbjct: 203 LSVDLYPQRIMCVSLHPGWVKTDM 226 >3O26-A nrPDB Length = 311 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 48/291 (16%), Positives = 88/291 (30%), Gaps = 88/291 (30%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG----DHLAFSCDVA 58 + V GG++GIG + + ++ G + + R++ A L + + DV Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 59 KE-HDVQNTFEELEKHLGRVNFLVNAAGINRDGL-------------------------- 91 + + + ++ H G+++ LVN AG+ + Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYEKP 132 Query: 92 ----LVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVG--------- 138 L+ E L N G + + + IVNV S G Sbjct: 133 EAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVSNET 192 Query: 139 ---------------------------------LKGNSGQ-SVYSASKGGLVGFSRALAK 164 G + Y+ SK L ++R LA Sbjct: 193 ALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRVLAN 252 Query: 165 EVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVF 215 ++ + + VN V PG V T+M + ++ V +F Sbjct: 253 KIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEG--------AEHVVRIALF 293 >1B15-A nrPDB Length = 254 Score = 116 bits (291), Expect = 8e-27, Method: Composition-based stats. Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 16/193 (8%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG----DLGGDHLAFSCDV 57 +K GIG ++ + ++ + VI +E A A + + + DV Sbjct: 5 NKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHTYDV 64 Query: 58 AKE-HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 + + +++ L V+ L+N AGI D + RT + N G + T Sbjct: 65 TVPVAESKKLLKKIFDQLKTVDILINGAGILDDHQIERT--------IAINFTGLVNTTT 116 Query: 117 AAMRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A + +++GG I N+ S+ G VYSASK +V F+ +LAK + Sbjct: 117 AILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGVTA 176 Query: 174 NVVAPGFVHTDMT 186 + PG T + Sbjct: 177 YSINPGITRTPLV 189 >1FJH-A nrPDB Length = 257 Score = 115 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 47/271 (17%), Positives = 96/271 (35%), Gaps = 58/271 (21%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 + + G + GIG A +++ G+++ I D++ Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE--------------VIADLSTAEGR 48 Query: 64 QNTFEELEKHL-GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 + ++ ++ LV AG+ ++ + + N G+ A + + Sbjct: 49 KQAIADVLAKCSKGMDGLVLCAGLGPQTKVL-------GNVVSVNYFGATELMDAFLPAL 101 Query: 123 IQQQGGSIVNVGSIV----GLKGNS------------------------GQSVYSASKGG 154 + + V + S+ N G Y+ SK Sbjct: 102 KKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNA 161 Query: 155 LVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKD-LKEEHLKKNI-----PLGRFGETIE 208 L R A +R+N +APG T + + L++ ++I P+GR E E Sbjct: 162 LTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPMGRRAEPSE 221 Query: 209 VAHAVVFLLE--SPYITGHVLVVDGGLQLIL 237 +A + FL+ + Y+ G +V+DGG+ ++ Sbjct: 222 MASVIAFLMSPAASYVHGAQIVIDGGIDAVM 252 >2O2S-A nrPDB Length = 315 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 58/288 (20%), Positives = 105/288 (36%), Gaps = 56/288 (19%) Query: 3 KVCAVFGGSR--GIGRAVAQLMARKGYRLAV---------------IARNLEGAKAAAGD 45 + V G + G G A+A+ +A G R+A+ R E K G Sbjct: 10 QTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLPDGS 69 Query: 46 LGGDHLAFSCDVA--------------------KEHDVQNTFEELEKHLGRVNFLVN--A 83 L + D A + ++ ++++ LG ++ LV+ A Sbjct: 70 LIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVHSLA 129 Query: 84 AGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNS 143 G L+ T + ++ + + + M +GGS V + + + Sbjct: 130 NGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM--NEGGSAVTLSYLAAERVVP 187 Query: 144 GQ-SVYSASKGGLVGFSRALAKEVA-RKKIRVNVVAPGFVHTDMTKDLKEEHLKKNI--- 198 G S++K L +R LA E + +RVN ++ G + + + + K I Sbjct: 188 GYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFIDYA 247 Query: 199 --------PLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 PL R + +V A +FLL + ++G L VD GL + Sbjct: 248 IDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAM 295 >4Q9N-A nrPDB Length = 298 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 55/282 (19%), Positives = 109/282 (38%), Gaps = 50/282 (17%) Query: 3 KVCAV--FGGSRGIGRAVAQLMARKGYRLA---------VIARNLEGAKAAA------GD 45 K+ + G G G +A+++A G + + +++LE K A G+ Sbjct: 9 KIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELSNGE 68 Query: 46 LGGDHLAFSCDVA--------------------KEHDVQNTFEELEKHLGRVNFLVNAAG 85 L + D + + V E+++KH G ++ LV++ Sbjct: 69 LLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVHSLA 128 Query: 86 INR--DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNS 143 + L+ T + ++ L T+ + M G S +++ + ++ Sbjct: 129 NSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM--NAGASTISLTYLASMRAVP 186 Query: 144 GQ-SVYSASKGGLVGFSRALAKEVARK-KIRVNVVAPGFVHTDMTKDL-----KEEHLKK 196 G +A+K L ++ LA E R+ +RVN ++ G + + K + ++ + Sbjct: 187 GYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGFIERMVDYYQD 246 Query: 197 NIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLI 236 PL E +V A FL+ + ITG L VD G ++ Sbjct: 247 WAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGANVM 288 >1MG5-A nrPDB Length = 255 Score = 110 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 46/196 (23%), Positives = 76/196 (38%), Gaps = 16/196 (8%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG----DLGGDHLAFSCDV 57 +K G GIG ++ + ++ + VI +E A A + + DV Sbjct: 6 NKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDV 65 Query: 58 AKE-HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116 + + + L V+ L+N AGI D + RT + N G + T Sbjct: 66 TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIERT--------IAVNYTGLVNTTT 117 Query: 117 AAMRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173 A + +++GG I N+GS+ G VYS +K +V F+ +LAK + Sbjct: 118 AILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTA 177 Query: 174 NVVAPGFVHTDMTKDL 189 V PG T + Sbjct: 178 YTVNPGITRTTLVHKF 193 >5LCX-A nrPDB Length = 316 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 45/269 (16%), Positives = 78/269 (28%), Gaps = 89/269 (33%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNL----EGAKAAAGDLG---GDHLAFSCDV 57 V G ++GIG + + +A KG + + +RN E + +L + DV Sbjct: 10 ALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDV 69 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGIN------RDGLLVRTKTEDMVSQLH------ 105 V ++ G+++ LVN AG++ + D + Sbjct: 70 TDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAGAK 129 Query: 106 -------------------------TNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIV--- 137 TN G +A + + IVNV S Sbjct: 130 EEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSFGSL 189 Query: 138 ---------GLKG-------------------------------NSGQSVYSASKGGLVG 157 G+ G + SK L Sbjct: 190 LLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAALNA 249 Query: 158 FSRALAKEVARKKIRVNVVAPGFVHTDMT 186 +++ AK+ +I N + PG+ TD+T Sbjct: 250 YTKIAAKKYPSFRI--NAICPGYAKTDIT 276 >1ENP-A nrPDB Length = 312 Score = 104 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 45/188 (23%), Positives = 79/188 (42%), Gaps = 13/188 (6%) Query: 58 AKEHDVQNTFEELEKHLGRVNFLVN--AAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 + VQ E + + G ++ LV+ A G L+ T + ++ + + + Sbjct: 111 SSNWTVQEAAECVRQDFGSIDILVHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLL 170 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ-SVYSASKGGLVGFSRALAKEVARK-KIRV 173 + M GG+ +++ I + G S++K L +R LA E RK IRV Sbjct: 171 SHFLPIM--NPGGASISLTYIASERIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRV 228 Query: 174 NVVAPGFVHTDMTKDL-----KEEHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHV 226 N ++ G + + K + E+ N P+ + EV +A FL+ + ITG Sbjct: 229 NTISAGPLGSRAAKAIGFIDTMIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGAT 288 Query: 227 LVVDGGLQ 234 + VD GL Sbjct: 289 IYVDNGLN 296 >2NTV-A nrPDB Length = 268 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 54/261 (20%), Positives = 92/261 (35%), Gaps = 32/261 (12%) Query: 3 KVCAVFG--GSRGIGRAVAQLMARKGYRLAVIARNLEGA-KAAAGDLGGDHLAFSCDVAK 59 K V G I +A++ G +L + + + A L DV Sbjct: 7 KRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIELDVQN 66 Query: 60 EHDVQNTFEELEKHLG---RVNFLVNAAGINR-----DGLLVRTKTEDMVSQLHTNLLGS 111 E + E + +G +++ +V++ G ED+ +H + Sbjct: 67 EEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGIHISTYSY 126 Query: 112 MLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 KA + +I GGSIV + + + + +K L +R +A+E + + Sbjct: 127 ASLAKALL--LIMNSGGSIVGM-DFDPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGV 183 Query: 172 RVNVVAPGFVHTDMTKD---------------LKEEHLKKNIPLG-RFGETIEVAHAVVF 215 R N+VA G + T L EE + P+G + VA V Sbjct: 184 RSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKTVCA 243 Query: 216 LLES--PYITGHVLVVDGGLQ 234 LL P TG ++ DGG Sbjct: 244 LLSEWLPATTGSIIYADGGAS 264 >5WQO-A nrPDB Length = 234 Score = 100 bits (249), Expect = 7e-22, Method: Composition-based stats. Identities = 45/216 (20%), Positives = 81/216 (37%), Gaps = 13/216 (6%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAFSCDVAKEH 61 + G SRGIG +A ++G ++ +AR + G +A A G A + D+ + Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRD--GLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + E L + R++ L+ AGI + E TN + + +A Sbjct: 69 CAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARALS 126 Query: 120 RTMIQQQGGSIVNVGSIVGLKG---NSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 +GG + + S + ++ +Y ASK L R+ E + ++ Sbjct: 127 G--RVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLL 184 Query: 177 APGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHA 212 PG+V T+M D + G + A Sbjct: 185 HPGWVRTEMGGD-SAPLSVEESAAGLVAAVEDAAGV 219 >2PTG-A nrPDB Length = 319 Score = 99.8 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 58/301 (19%), Positives = 107/301 (35%), Gaps = 69/301 (22%) Query: 3 KVCAVFGG--SRGIGRAVAQLMARKGYRLAV----------------------IARNLEG 38 K V G S G G A+ +L+ G R+ V E Sbjct: 10 KTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYAQEP 69 Query: 39 AKAAAGDLGGDHLAFSCD------------------VAKEH--------DVQNTFEELEK 72 + A + + D V+ + E + Sbjct: 70 SSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEAVRA 129 Query: 73 HLGRVNFLVN--AAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSI 130 +G+++ LV+ A G L++T + ++ + ++ + + + M + GGS Sbjct: 130 DVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE--GGSA 187 Query: 131 VNVGSIVGLKGNSGQSV-YSASKGGLVGFSRALAKEVAR-KKIRVNVVAPGFVHTDMTKD 188 + + I K G S++K L R LA E R + +RVN ++ G + + Sbjct: 188 LALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSRAASA 247 Query: 189 LKE-----------EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQL 235 + + ++ + N PL + E+ +V A +FLL + +TG L VD GL Sbjct: 248 IGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDNGLHA 307 Query: 236 I 236 + Sbjct: 308 M 308 >4OYR-A nrPDB Length = 289 Score = 99.0 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 51/261 (19%), Positives = 91/261 (34%), Gaps = 32/261 (12%) Query: 3 KVCAVFG--GSRGIGRAVAQLMARKGYRLAVIARNLEGA-KAAAGDLGGDHLAFSCDVAK 59 K V G I +A++ +G +L + + + L DV Sbjct: 28 KRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQN 87 Query: 60 EHDVQNTFEELEKHLG---RVNFLVNAAGINR-----DGLLVRTKTEDMVSQLHTNLLGS 111 E + + + + +G +++ +V++ G D+ +H + Sbjct: 88 EEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSY 147 Query: 112 MLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 KA + M GGSIV + + + + +K L +R +A+E + + Sbjct: 148 ASMAKALLPIM--NPGGSIVGM-DFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGV 204 Query: 172 RVNVVAPGFVHTDMTKD---------------LKEEHLKKNIPLG-RFGETIEVAHAVVF 215 R N+VA G + T L EE + P+G + VA V Sbjct: 205 RSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCA 264 Query: 216 LLES--PYITGHVLVVDGGLQ 234 LL P TG ++ DGG Sbjct: 265 LLSDWLPATTGDIIYADGGAH 285 >3F4B-A nrPDB Length = 323 Score = 95.2 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 41/209 (19%), Positives = 81/209 (38%), Gaps = 35/209 (16%) Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRD--GLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 ++ + G+++ LV++ R+ L+ T + + + + + CK Sbjct: 106 SIEEVANLIYNKYGKISMLVHSLANGREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFC 165 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSV-YSASKGGLVGFSRALAKEVARK-KIRVNVVA 177 + M GGS+V++ K G S++K L +R LA + RK IR+N ++ Sbjct: 166 KFM--NSGGSVVSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTIS 223 Query: 178 PGFVHTDMTKDLKE---------------------------EHLKKNIPLGRFGETIEVA 210 G + + + + ++ +K PL + + +V Sbjct: 224 AGPLKSRAATAINKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVG 283 Query: 211 HAVVFLLE--SPYITGHVLVVDGGLQLIL 237 FLL S +TG + VD GL ++ Sbjct: 284 SVASFLLSKESSAVTGQTIYVDNGLNIMF 312 >5TQV-A nrPDB Length = 233 Score = 90.9 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 77/188 (40%), Gaps = 13/188 (6%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G SRG+GR + R G+ + AR+ A LG A D+ + Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAAL-RALGAHAHAL--DITQPEQ 66 Query: 63 VQNTFEELEKHLGRVNFLVNAAGI--NRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 + +L+ R++ V +G+ R + ++D + +HTN+ G M + Sbjct: 67 IAALGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLL-PILL 123 Query: 121 TMIQQQGGSIVNVGSIVGLKGNSGQSV---YSASKGGLVGFSRALAKEVARKKIRVNVVA 177 +++ G + V S +G + + Y ASK L R + + + + Sbjct: 124 PLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIAS--LQTRHAACISLH 181 Query: 178 PGFVHTDM 185 PG+V TDM Sbjct: 182 PGWVRTDM 189 >2O2Y-A nrPDB Length = 349 Score = 82.1 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 42/231 (18%), Positives = 79/231 (34%), Gaps = 58/231 (25%) Query: 62 DVQNTFEELEKHLGRVNFLVN---AAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 +++ + + G++N LV+ A L+ T + + L + + CK Sbjct: 111 TIEDVANLIHQKYGKINMLVHSLANAK-EVQKDLLNTSRKGYLDALSKSSYSLISLCKYF 169 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSV-YSASKGGLVGFSRALAKEVAR-KKIRVNVV 176 + M Q SI+++ K G S++K L +R LA + R IR+N + Sbjct: 170 VNIMKPQS--SIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTI 227 Query: 177 APGFVHTDMTKDLKE--------------------------------------------- 191 + G + + + + Sbjct: 228 SAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFID 287 Query: 192 ---EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGGLQLIL 237 E+ +K PL + + ++ FLL S ITG + VD GL ++ Sbjct: 288 YAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMF 338 >3SLK-A nrPDB Length = 795 Score = 75.2 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 40/186 (21%), Positives = 71/186 (38%), Gaps = 26/186 (13%) Query: 4 VCAVFGGSRGIGRAVAQLMA-RKGYR-LAVIARN---LEGAKAAAGDL---GGDHLAFSC 55 V GG+ +G VA+ + +G R L +++R GA L G + +C Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 DVA + + + +V+AAG+ DG+ E + L + G+ Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGF----------SRALA-K 164 + + ++V S+ G+ G+ GQ Y+A+ L +R+LA Sbjct: 651 ELIDPDV------ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLAWG 704 Query: 165 EVARKK 170 A Sbjct: 705 PWAEHG 710 >4LIS-A nrPDB Length = 371 Score = 68.2 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 26/171 (15%), Positives = 53/171 (30%), Gaps = 31/171 (18%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIA----RNLEGAKAAAGDLGGDHLAFSCDVAKE 60 V GG+ IG + GY++ V + E G DV E Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 F+++ + ++ +++ A + G + H N+ G++ +R Sbjct: 66 ----AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLD----YYHVNVYGTICL----LR 113 Query: 121 TMIQQQGGSIVNVGSIVGLK---------------GNSGQSVYSASKGGLV 156 +M++ +IV S + Y +K + Sbjct: 114 SMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >3ORF-A nrPDB Length = 251 Score = 63.2 bits (153), Expect = 8e-11, Method: Composition-based stats. Identities = 40/209 (19%), Positives = 71/209 (33%), Gaps = 15/209 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 M K V GGS +G V + K + I + +F+ + E Sbjct: 21 MSKNILVLGGSGALGAEVVKFFKSKSWNTISIDFR---------ENPNADHSFTIKDSGE 71 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLV-RTKTEDMVSQLHTNLLGSMLTCKAAM 119 ++++ E++ +V+ V AAG G + + + NL + + Sbjct: 72 EEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIGA 131 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVA--RKKIRVNVVA 177 + + QGG V G+ L SG Y A+K + LA E + Sbjct: 132 KLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGIL 189 Query: 178 PGFVHTDMTKD-LKEEHLKKNIPLGRFGE 205 P + T + + + + PL E Sbjct: 190 PVTLDTPTNRKYMSDANFDDWTPLSEVAE 218 >2PK3-A nrPDB Length = 321 Score = 63.2 bits (153), Expect = 9e-11, Method: Composition-based stats. Identities = 43/258 (16%), Positives = 86/258 (33%), Gaps = 49/258 (18%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + G + +G+ +A + + + +RN E + S D+ V+ Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKL-------PNVEMISLDIMDSQRVK 67 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 ++ + +++ + A V+ + TN+ G++ A + + Sbjct: 68 KVISDI-----KPDYIFHLAA----KSSVKDSWLNKKGTFSTNVFGTLHVLDAVRDSNLD 118 Query: 125 QQGGSIVNVGS-------------IVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 I+ +GS + S Y SK + +R K I Sbjct: 119 C---RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDII 175 Query: 172 ---RVNVVAP----GFVHTDMTKDLKEEHLKKNIPLGRFG---------ETIEVAHAVVF 215 N + P GFV D K + + ++K P+ + G + ++ A + Sbjct: 176 HTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAY-W 234 Query: 216 LLESPYITGHVLVVDGGL 233 LL TG V V G+ Sbjct: 235 LLSQYGKTGDVYNVCSGI 252 >6BWL-A nrPDB Length = 328 Score = 57.4 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 44/267 (16%), Positives = 82/267 (30%), Gaps = 59/267 (22%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGD---HLAFSCDVAKEH 61 V GG+ IGR V + + + + + ++ A + D D+ + Sbjct: 3 ILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDKK 62 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 V FE L AA IN V+ +D + + +G+ + + Sbjct: 63 LVAQLFEN--NSFDLCYHL--AASIN-----VQDSIDDARATFENDTIGTFNLLEQCLNY 113 Query: 122 ----------MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171 M+ + N+ I L S Y+ SK + K+ Sbjct: 114 DVKMVFMSTCMVYDKA---TNIQGISELDPIKPASPYAGSKIAAENMVLSY---YYAYKL 167 Query: 172 RVNVVAPGFVHTDMTKDLKEEHLKK--------NIPLGRFGE---------TIEVAHAVV 214 V V+ P + K E + N+PL +G+ + A Sbjct: 168 PVVVIRPFNTYGPFQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCAD--- 224 Query: 215 FLLESPYI-----------TGHVLVVD 230 F++ + Y TG + ++ Sbjct: 225 FVVAAGYSAKANGHIINAGTGQDISIN 251 >3RFT-A nrPDB Length = 267 Score = 56.3 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 48/170 (28%), Gaps = 37/170 (21%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G + +GR + + +A L + + G + CD+A + Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSP------LDPAGPNEECVQCDLADANA 57 Query: 63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 V + +V+ GI+ + L N++G +AA Sbjct: 58 VNAMVA-------GCDGIVHLGGISVEKPFE--------QILQGNIIGLYNLYEAA---- 98 Query: 123 IQQQGGSIVNVGSIVGLKGNSGQ------------SVYSASKGGLVGFSR 160 IV S + +Y SK +R Sbjct: 99 RAHGQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLAR 148 >1UDA-A nrPDB Length = 338 Score = 55.1 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 29/170 (17%), Positives = 53/170 (31%), Gaps = 29/170 (17%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIA---RNLEGAKAAAGDLGGDHLA-FSCDVAKE 60 V GGS IG + + G+ + ++ + LGG H D+ E Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNE 62 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 E+ ++ +++ AG+ G V+ E N+ G++ A Sbjct: 63 ----ALMTEILHDH-AIDTVIHFAGLKAVGESVQKPLE----YYDNNVNGTLRLISA--- 110 Query: 121 TMIQQQGGSIVNVGS------------IVGLKGNSGQSVYSASKGGLVGF 158 M + + S + + QS Y SK + Sbjct: 111 -MRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQI 159 >1OOE-A nrPDB Length = 236 Score = 54.4 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 31/191 (16%), Positives = 64/191 (33%), Gaps = 14/191 (7%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V+GG +G A+ + + GY + I + A D ++ + Q Sbjct: 6 VIVYGGKGALGSAILEFFKKNGYTVLNIDLS-------ANDQADSNILVDGNKNWTEQEQ 58 Query: 65 NTFEELEKHLGR--VNFLVNAAGINRDGLLVRTK-TEDMVSQLHTNLLGSMLTCKAAMRT 121 + E+ L V+ + AG G ++ + ++ S + K A Sbjct: 59 SILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSSAIAAKLATTH 118 Query: 122 MIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE--VARKKIRVNVVAPG 179 + + GG + G+ + Y +K + + +LA + V + P Sbjct: 119 L--KPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNSAVLTIMPV 176 Query: 180 FVHTDMTKDLK 190 + T M + Sbjct: 177 TLDTPMNRKWM 187 >1Z45-A nrPDB Length = 699 Score = 54.0 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 25/176 (14%), Positives = 50/176 (28%), Gaps = 32/176 (18%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIA----RNLEGAKAAAGDLGGDHLAFSCDV 57 K+ V GG+ IG + GY V + + D+ Sbjct: 11 SKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDL 70 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++ F+E +++ +++ AG+ G + H N+LG+++ Sbjct: 71 CDRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIPL----RYYHNNILGTVVL--- 118 Query: 118 AMRTMIQQQGGSIVNVGSIVGLK---------------GNSGQSVYSASKGGLVGF 158 + M Q V S + Y +K + Sbjct: 119 -LELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENI 173 >1DIR-A nrPDB Length = 241 Score = 50.9 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 41/231 (17%), Positives = 76/231 (32%), Gaps = 30/231 (12%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 + V+GG +G Q + + +A + + + Sbjct: 8 RRVLVYGGRGALGSRCVQAFRARNWWVA-------SIDVVENEEASASVIVKMTDSFTEQ 60 Query: 63 VQNTFEELEKHLG--RVNFLVNAAGINRDGLLVRTKT-EDMVSQLHTNLLGSMLTCKAAM 119 E+ K LG +V+ ++ AG G ++ ++ S ++ A Sbjct: 61 ADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLAT 120 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALA--KEVARKKIRVNVVA 177 + + + GG + G+ L G G Y +KG + ++LA V Sbjct: 121 KHLKE--GGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVL 178 Query: 178 PGFVHTDMT-KDLKEEHLKKNIPLGRFGETIEVAHAVVFLLES--PYITGH 225 P + T M K + E PL FL+E+ +ITG+ Sbjct: 179 PVTLDTPMNRKSMPEADFSSWTPLE-------------FLVETFHDWITGN 216 >1I3M-A nrPDB Length = 348 Score = 50.1 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 55/185 (29%), Gaps = 37/185 (20%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIA----------RNLEGAKAAAGDLGGDH 50 M + V GG+ IG + GY VI E + G Sbjct: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60 Query: 51 LAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLG 110 D+ + +Q F++ +++ AG+ G V+ + NL G Sbjct: 61 EFEEMDILDQGALQRLFKKY-----SFMAVIHFAGLKAMGESVQKPLD----YYRVNLTG 111 Query: 111 SMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ-------------SVYSASKGGLVG 157 ++ + M ++V S + GN + Y SK + Sbjct: 112 TI----QLLEIMKAHGVKNLVF-SSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEE 166 Query: 158 FSRAL 162 R L Sbjct: 167 MIRDL 171 >2GN9-A nrPDB Length = 344 Score = 50.1 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 54/154 (35%), Gaps = 21/154 (13%) Query: 2 DKVCAVFGGSRGIGRAVAQLMAR--KGYRLAVIARNLEGAKAAAGDLGG-DHLAFSCDVA 58 ++ + GG+ G+ + + ++ V +R+ A + F DV Sbjct: 21 NQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRFFIGDVR 80 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 + E V+ ++AA + + E + TN++G+ A Sbjct: 81 DLERLNYALE-------GVDICIHAAALKHVPIAEYNPLE----CIKTNIMGASNVINAC 129 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASK 152 ++ I Q ++ + + ++Y A+K Sbjct: 130 LKNAISQ----VIALSTDKAANPI---NLYGATK 156 >2Q1W-A nrPDB Length = 333 Score = 49.3 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 37/193 (19%), Positives = 63/193 (32%), Gaps = 40/193 (20%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 M KV + G IG +A+L+ +G ++ I G + D + +A Sbjct: 21 MKKV-FITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDH-PNLTFVEGSIADH 78 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V +L+ + +V+ A +D +D + TN +G +AA Sbjct: 79 ALVNQLIGDLQ-----PDAVVHTAASYKD-------PDDWYNDTLTNCVGGSNVVQAA-- 124 Query: 121 TMIQQQGGSIVN--VGSIVGLKG-----------NSGQSVYSASKGG---------LVGF 158 + G V G+K N S Y+ SK L Sbjct: 125 --KKNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGLDFV 182 Query: 159 SRALAKEVARKKI 171 + LA V + + Sbjct: 183 TFRLANVVGPRNV 195 >2NNL-D nrPDB Length = 337 Score = 47.8 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 42/257 (16%), Positives = 77/257 (29%), Gaps = 54/257 (21%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAF-SCD 56 + V G S IG + + +GY + R+ K L HL D Sbjct: 5 SETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKAD 64 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED-MVSQLHTNLLGSMLTC 115 +A E + G+ + +++D + + G + Sbjct: 65 LADEGSFDEAIKG-------------CTGVFHVATPMDFESKDPENEVIKPTIEGMLGIM 111 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ-SVY----------SASK---GGLVGFSRA 161 K+ + +V S + Q VY +K + S+ Sbjct: 112 KSCAAAKTVR---RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKT 168 Query: 162 LAKEVA-----RKKIRVNVVAPG-----FVHTDMTKDL--------KEEHLKKNIPLGRF 203 LA++ A I + P F+ + M L E I G+F Sbjct: 169 LAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQF 228 Query: 204 GETIEVAHAVVFLLESP 220 ++ +A ++L E+P Sbjct: 229 VHLDDLCNAHIYLFENP 245 >4PVC-A nrPDB Length = 342 Score = 47.0 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 21/140 (15%), Positives = 50/140 (35%), Gaps = 16/140 (11%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGD---HLAFSCDVAKEH 61 V G + I + + L+ ++ Y++ AR+ E A+ G + + D++K Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQL-HTN-LLGSMLTCKAAM 119 + F+ KH + +++ A + + N + G + + K Sbjct: 63 AFDHVFQ---KHGKDIKIVLHTA----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115 Query: 120 RTMIQQQGGSIVNVGSIVGL 139 ++ +V S + Sbjct: 116 ADSVE----RVVLTSSYAAV 131 >3HFS-A nrPDB Length = 338 Score = 46.3 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 43/269 (15%), Positives = 79/269 (29%), Gaps = 79/269 (29%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAA-----AGDLGGDHLAFSCDV 57 K V GG+ + + +L+ +KGY + R+ + K +LG D F D+ Sbjct: 10 KTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELG-DLKIFRADL 68 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 E + +F+ + A DM+ + G + KA Sbjct: 69 TDELSFEAPIA-------GCDFVFHVA--TPVHFASEDPENDMIKPA---IQGVVNVMKA 116 Query: 118 AMRTMIQQQGGSIVNVGSIVGLK------------------------GNSGQSVYSASKG 153 R + ++ S + Y ASK Sbjct: 117 CTRAKSVK---RVILTSSAAAVTINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKT 173 Query: 154 GLVGFSRALAKEVARKK----IRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEV 209 + A + A + I V + T M + +I Sbjct: 174 ----LAEKAAWKFAEENNIDLITV-------IPTLMAGSSLTSDVPSSI----------- 211 Query: 210 AHAVVFLLESPYITGHVLVVDG--GLQLI 236 + L ITG+ +++G G+Q++ Sbjct: 212 -GLAMSL-----ITGNEFLINGMKGMQML 234 >1VL0-A nrPDB Length = 292 Score = 46.3 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 51/169 (30%), Gaps = 43/169 (25%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + G + +GR + + + KG + VI +++ D+ V Sbjct: 15 ILITGANGQLGREIQKQL--KGKNVEVIPTDVQDL----------------DITNVLAVN 56 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 F E + N ++N A V E N +G AA Sbjct: 57 KFFNE-----KKPNVVINCAAHT----AVDKCEEQYDLAYKINAIGPKNLAAAAY----- 102 Query: 125 QQGGSIVNVGSIVGLKGNS-----------GQSVYSASKGGLVGFSRAL 162 G IV + + G + QS Y +K F +AL Sbjct: 103 SVGAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >3ENK-A nrPDB Length = 341 Score = 45.9 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 21/70 (30%), Gaps = 4/70 (5%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIA----RNLEGAKAAAGDLGGDHLAFSCDVAK 59 V GG+ IG A + GY + + E G DV+ Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSD 66 Query: 60 EHDVQNTFEE 69 E + F+ Sbjct: 67 ERALARIFDA 76 >3SC6-A nrPDB Length = 287 Score = 45.9 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 23/152 (15%), Positives = 50/152 (32%), Gaps = 31/152 (20%) Query: 28 RLAVIARNLEGAKAAAGDLGGDHLAF------SCDVAKEHDVQNTFEELEKHLGRVNFLV 81 R+ + N + K +L + D+ VQ +E+ R + ++ Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKLLDITNISQVQQVVQEI-----RPHIII 61 Query: 82 NAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKG 141 + A + V ++ N +G+ A ++ G +V + + +G Sbjct: 62 HCAAYTK----VDQAEKERDLAYVINAIGARNV--AVASQLV---GAKLVYISTDYVFQG 112 Query: 142 -----------NSGQSVYSASKGGLVGFSRAL 162 + ++Y ASK F + L Sbjct: 113 DRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >4G5H-A nrPDB Length = 363 Score = 45.9 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 22/157 (14%), Positives = 57/157 (36%), Gaps = 20/157 (12%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAAAGDLGGDHL-AFSCDVAK 59 DK+ + GG+ G AV + + + + +R+ + L + DV Sbjct: 25 DKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYIGDVRD 84 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 V+ + V+++ +AA + + E + TN++G+ ++A+ Sbjct: 85 SQSVETAMRD-------VDYVFHAAALKQVPSCEFFPVEAVK----TNIIGTENVLQSAI 133 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLV 156 +++ ++ + + + SK + Sbjct: 134 HQNVKK----VICLSTDKAAYPI---NAMGISKAMME 163 >4J2O-A nrPDB Length = 363 Score = 44.7 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 57/157 (36%), Gaps = 20/157 (12%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAA-AGDLGGDHLAFSCDVAK 59 DKV + GG+ G AV + + + + +R+ + + DV Sbjct: 23 DKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYIGDVRD 82 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 + + N V+++ +AA + + E + TN+LG+ +AA+ Sbjct: 83 YNSILNATR-------GVDYIYHAAALKQVPSCEFHPMEAVK----TNVLGTENVLEAAI 131 Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLV 156 + ++ +V + + + + SK + Sbjct: 132 QNHVK----RVVCLSTDKAVYPI---NAMGISKAMME 161 >4R1T-A nrPDB Length = 337 Score = 44.3 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 19/149 (12%), Positives = 42/149 (28%), Gaps = 24/149 (16%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK----AAAGDLGGDHLAFSCDVA 58 +V V G I + +++ KGY + RN + K D+ Sbjct: 11 QVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKADLL 70 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 ++ + + + A D + ++G+ AA Sbjct: 71 DYQSLREAIN-------GCDGVFHTASPVTDDPEQMVEPA---------VIGTKNVINAA 114 Query: 119 MRTMIQQQGGSIVNVGSIVGLKGNSGQSV 147 ++ +V SI + + + Sbjct: 115 AEANVR----RVVFTSSIGAVYMDPNRDP 139 >5N2I-A nrPDB Length = 232 Score = 44.0 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 30/63 (47%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 AV GG+ GR +A+ A G+ + + +R+ E A+A A +LG D A + Sbjct: 22 IAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAG 81 Query: 65 NTF 67 + Sbjct: 82 DVV 84 >1GPJ-A nrPDB Length = 404 Score = 43.2 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 16/102 (15%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 DK V G +G+ VA+ + +G R + V R E A A DLGG+ + Sbjct: 167 DKTVLVVGAGE-MGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVR-------- 217 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVS 102 F+EL HL R + +V+A + V E + Sbjct: 218 ------FDELVDHLARSDVVVSATAAPHPVIHVDDVREALRK 253 >4R1U-A nrPDB Length = 349 Score = 42.8 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 21/149 (14%), Positives = 42/149 (28%), Gaps = 24/149 (16%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK----AAAGDLGGDHLAFSCDV 57 D+ V G I + +L+ +GY + RN E K D+ Sbjct: 27 DQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKVDL 86 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 +Q+ + + + A D + + G+ A Sbjct: 87 LDLQSIQSVVH-------GCHGVFHTASPVTDNPDEMLEPA---------VNGTKNVIIA 130 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQS 146 + ++ +V SI + + S Sbjct: 131 SAEAKVR----RVVFTSSIGTVYMDPNTS 155 >1OC2-A nrPDB Length = 348 Score = 42.8 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 40/123 (32%), Gaps = 15/123 (12%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL---EGAKA-AAGDLGGDHLAFSCDVA 58 K V GG+ IG + + V + G KA LG D+A Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 V + + +V+ A + + D +HTN +G+ +AA Sbjct: 65 DAELVDKLAAKA-------DAIVHYAAESHN----DNSLNDPSPFIHTNFIGTYTLLEAA 113 Query: 119 MRT 121 + Sbjct: 114 RKY 116 >5YWN-A nrPDB Length = 334 Score = 42.4 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 45/257 (17%), Positives = 85/257 (33%), Gaps = 47/257 (18%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 M V G + + + + L+ KGY++ R+ E G D V K Sbjct: 1 MTTSVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYE---VVKV 57 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTN-LLGSMLTCKAAM 119 + + F+E K V ++ A TE + N + + K Sbjct: 58 LEQKGAFDEALKKHPEVTIFLHTA---SPVTFEVEDTEKEILIPAINGTKYVLQSIKDVA 114 Query: 120 RTMIQQQGGSIVNVGSIVGL--------------KGNSGQSVYSASK-GGLVGF--SRAL 162 + +V S+V + + + Y SK G++ + S+ Sbjct: 115 PQIT-----RVVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQF 169 Query: 163 A-------KEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVF 215 A E + ++ V P ++ K+E +K G + E+ ++V+ Sbjct: 170 AERAAWEFVEQEKPNFALSTVNPVYI---FGPQAKDEEVK-----GTLNHSAEMVNSVLK 221 Query: 216 LLES---PYITGHVLVV 229 L + P TG + V Sbjct: 222 LNKDDDVPATTGTFIDV 238 >1ZZE-A nrPDB Length = 342 Score = 42.4 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 21/141 (14%), Positives = 48/141 (34%), Gaps = 13/141 (9%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA-FSCDVAKEHDV 63 V G + + V + + GY++ AR+ + F V ++ Sbjct: 14 VLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLK 73 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 Q ++E+ K AAG+ +V + + + G++ +AA T Sbjct: 74 QGAYDEVIKG---------AAGVAHIASVVSFSNK-YDEVVTPAIGGTLNALRAAAATPS 123 Query: 124 QQQGGSIVNVGSIVGLKGNSG 144 ++ ++ ++ L Sbjct: 124 VKRF--VLTSSTVSALIPKPN 142 >1GY8-A nrPDB Length = 397 Score = 42.4 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 58/207 (28%), Gaps = 53/207 (25%) Query: 5 CAVFGGSRGIGRAVAQLMARK-GYRLAVIAR---------NLEGAKAAAGDLGGD----- 49 V GG+ IG + + R + + ++ ++E + A L Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 50 ------HLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQ 103 DV E + F G ++ +V+ G VR Sbjct: 65 PWADRYAALEVGDVRNEDFLNGVF----TRHGPIDAVVHMCAFLAVGESVRDPL----KY 116 Query: 104 LHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQ------------------ 145 N++G + +A M+ + I+ S + GN Sbjct: 117 YDNNVVGILRLLQA----MLLHKCDKIIF-SSSAAIFGNPTMGSVSTNAEPIDINAKKSP 171 Query: 146 -SVYSASKGGLVGFSRALAKEVARKKI 171 S Y SK R A+ K I Sbjct: 172 ESPYGESKLIAERMIRDCAEAYGIKGI 198 >2PZM-A nrPDB Length = 330 Score = 42.0 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 47/121 (38%), Gaps = 13/121 (10%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + GG+ +G + + +G+ + VI G + + G + V ++ Sbjct: 23 ILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGLSV-IEGSVTDAGLLE 81 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 F+ + +V++A +D +D TN+ GS+ KAA + ++ Sbjct: 82 RAFDSFKPTH-----VVHSAAAYKD-------PDDWAEDAATNVQGSINVAKAASKAGVK 129 Query: 125 Q 125 + Sbjct: 130 R 130 >4QUK-A nrPDB Length = 319 Score = 41.6 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 44/141 (31%), Gaps = 14/141 (9%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V V G S I + +L+ +GY + R+ K D AKE Sbjct: 2 VVCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKV-------DHLVKLDGAKE--R 52 Query: 64 QNTFEELEKHLGRVNFLV-NAAGINRDG-LLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 F+ G + +V G+ + + L G++ + ++ Sbjct: 53 LQLFKANLLEEGAFDSVVQGCHGVFHTASPFYHDVKDPQAELIDPALKGTLNVLNSCAKS 112 Query: 122 MIQQQGGSIVNVGSIVGLKGN 142 + +V SI + N Sbjct: 113 PSLK---RVVLTSSIAAVAYN 130 >1R66-A nrPDB Length = 337 Score = 41.3 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 44/263 (16%), Positives = 74/263 (28%), Gaps = 51/263 (19%) Query: 6 AVFGGSRGIGRAVAQLMARKGY-------RLAVIA---RNLEGAKAAAGDLGGDHLAFSC 55 V GG+ IG + + G + V+ A A D Sbjct: 4 LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHG 62 Query: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115 D+ L + L V+ +V+ A + V TN+ G+ Sbjct: 63 DIRDAG-------LLARELRGVDAIVHFAAESH----VDRSIAGASVFTETNVQGTQTLL 111 Query: 116 KAAMRTMIQQQGGSIVNVG-----------SIVGLKGNSGQSVYSASKGGLVGFSRALAK 164 + A+ G +V+V S S Y+ASK G +RA + Sbjct: 112 QCAVDA----GVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHR 167 Query: 165 EVARK-KIR--VNVVAPG--------FVHTDMTKDLKEEHLKKNIPLGRFGETIE-VAHA 212 +I N P T++ + + T + Sbjct: 168 TYGLDVRITRCCNNYGPYQHPEKLIPLFVTNLLDGGTLPLYGDGANVREWVHTDDHCRGI 227 Query: 213 VVFLLESPYITGHVLVVDGGLQL 235 + L G + + GGL+L Sbjct: 228 ALVLAGGRA--GEIYHIGGGLEL 248 >5B6K-A nrPDB Length = 366 Score = 40.9 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 20/141 (14%), Positives = 47/141 (33%), Gaps = 18/141 (12%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL---GGDHLAFSCDVAKE 60 V G + I + V + + + Y++ R+ E + G + D++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 61 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 F+ + + G+ + V + T D+ L L+ ++ K + Sbjct: 83 ----TAFDHVFEKHGK-DIKV----VLHTASPFHFNTTDIEKDL---LIPAVNGTKGILE 130 Query: 121 TMIQ---QQGGSIVNVGSIVG 138 ++ + Q +V S Sbjct: 131 SIKKYAAQTVERVVVTSSFAA 151 >4EJ0-A nrPDB Length = 342 Score = 40.9 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 27/161 (16%), Positives = 44/161 (27%), Gaps = 29/161 (18%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V G + IG + + + +G + NL A C++ D Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKN-------LVDCEIDDYLDK 66 Query: 64 QNTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 122 E G+V + +G T D + N S A + Sbjct: 67 TEFVERFARGDFGKVR------AVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACL--- 117 Query: 123 IQQQGGSIVNVGSIVGLKGN----------SGQSVYSASKG 153 QG + S G+ + +VY SK Sbjct: 118 --AQGAQFLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >1RPN-A nrPDB Length = 335 Score = 40.5 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 3/70 (4%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLA-VIARNLEGAKAAAGDLG--GDHLAFSCDV 57 M + V G + G +A+L+ KGYR+ ++AR + +LG GD D+ Sbjct: 13 MTRSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDGDM 72 Query: 58 AKEHDVQNTF 67 A VQ Sbjct: 73 ADACSVQRAV 82 >6ACF-A nrPDB Length = 367 Score = 39.7 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%), Gaps = 7/61 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL------AFSCD 56 KV AV G + + + + +G +L V N E A + G + CD Sbjct: 174 KVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYGVECD 232 Query: 57 V 57 + Sbjct: 233 I 233 >1KEU-A nrPDB Length = 361 Score = 39.3 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 30/203 (14%), Positives = 62/203 (30%), Gaps = 43/203 (21%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAV------IARNLEGAKAAAGDLGGDHLAFSCDVA 58 + GG+ IG AV + + + V A NLE + + D+ Sbjct: 3 ILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISE--SNRYNFEHADIC 60 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 ++ FE+ + + +++ A + + + + TN++G+ + A Sbjct: 61 DSAEITRIFEQYQ-----PDAVMHLAAESHVDRSITGPA----AFIETNIVGTYALLEVA 111 Query: 119 MRTMI-----QQQGGSI--VNVGSIVGLKGNS-------------------GQSVYSASK 152 + ++ ++ + G + S YSASK Sbjct: 112 RKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASK 171 Query: 153 GGLVGFSRALAKEVARKKIRVNV 175 RA + I N Sbjct: 172 ASSDHLVRAWRRTYGLPTIVTNC 194 >6GCS-E nrPDB Length = 375 Score = 38.9 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 40/124 (32%), Gaps = 18/124 (14%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL--AFSCDVAKEH 61 VFG + +G + +A+ G + V R E AK G + D+ Sbjct: 55 TATVFGANGFLGSYLTAKLAKHGTTVVVPYR-EEMAKRHLKVTGDLGVVNFLEMDLRNLE 113 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + + +VN G +T++ ++ G+ +A + Sbjct: 114 SIDEAVR-------HSDIVVNLIG-------REYETKNFN-YYDVHVEGARRIAEAVKKH 158 Query: 122 MIQQ 125 I + Sbjct: 159 NIAR 162 >5F5N-A nrPDB Length = 289 Score = 38.9 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 26/69 (37%), Gaps = 1/69 (1%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 ++ V G + G A + + +G + + R+ G AA + D+ + Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDP-GTDAARALAAAGVSLVTGDLNDQA 59 Query: 62 DVQNTFEEL 70 ++ ++ Sbjct: 60 SLRAAMADV 68 >2C20-A nrPDB Length = 330 Score = 38.9 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 26/170 (15%), Positives = 52/170 (30%), Gaps = 37/170 (21%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + GG+ IG + + +G + V+ NL+ A G ++ D+ + ++ Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVD-NLQTGHEDAITEGAK--FYNGDLRDKAFLR 60 Query: 65 NTFE----ELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 + F E H + LV G++ + L + N+ G+ L M Sbjct: 61 DVFTQENIEAVMHFAA-DSLV---GVSMEKPL---------QYYNNNVYGA-LCLLEVMD 106 Query: 121 TMIQQQGGSIVNVGSIVGLKGNS------------GQSVYSASKGGLVGF 158 + S G + Y +K + Sbjct: 107 EFKVDKF----IFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKM 152 >2HUN-A nrPDB Length = 336 Score = 38.2 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 54/169 (31%), Gaps = 28/169 (16%) Query: 6 AVFGGSRGIGRAVAQLMARKG--YRLAVIAR-----NLEGAKAAAGDLGGDHLAFSCDVA 58 V GG IG + + K + + I + N K D + DVA Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDP--RYTFVKGDVA 64 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 V+ +V+ +V+ A + + + LH+N++G+ ++ Sbjct: 65 DYELVKELVR-------KVDGVVHLAAESHVDRSISSPEI----FLHSNVIGTYTLLESI 113 Query: 119 MRTMIQQQGGSI--------VNVGSIVGLKGNSGQSVYSASKGGLVGFS 159 R + + + + GS S YSA+K Sbjct: 114 RRENPEVRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLV 162 >2Q4B-A nrPDB Length = 253 Score = 38.2 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 9/78 (11%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V G S G+ + ++G +A+ L + +GG+ F D+ + Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGSD-KFVAKGLVRSAQGKEKIGGEADVFIGDITDADSI 63 Query: 64 QNTFEELEKHLGRVNFLV 81 F+ ++ LV Sbjct: 64 NPAFQ-------GIDALV 74 >5K1S-A nrPDB Length = 362 Score = 37.4 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 27/77 (35%), Gaps = 6/77 (7%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA-----FSCDVA 58 + G S G+G + QL G R+ + + +A + + F+ DV Sbjct: 186 TVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFASDVR 245 Query: 59 KEHDVQNTFEELEKHLG 75 K + + +G Sbjct: 246 KRTQ-GAGVDVAVEIVG 261 >4WPG-A nrPDB Length = 289 Score = 37.0 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 20/138 (14%), Positives = 40/138 (28%), Gaps = 31/138 (22%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + G + +G + L+ +G + D+ E V+ Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVD------------------VAEMDITNEDKVE 48 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 F +++ L + + A E N+ GS KA + Sbjct: 49 AVFAQVKPTL-----VYHCAAYTAVDAAED---EGKALNEAINVTGSENIAKACGKY--- 97 Query: 125 QQGGSIVNVGSIVGLKGN 142 G ++V + + GN Sbjct: 98 --GATLVYISTDYVFDGN 113 >4KTT-E nrPDB Length = 327 Score = 36.6 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 22/161 (13%), Positives = 46/161 (28%), Gaps = 35/161 (21%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 ++ V G + +GRAV + + + K ++ + Sbjct: 21 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK-----------FEQVNLLDSN 69 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 V + + + H +V+ A R ++ N+ S K A Sbjct: 70 AVHHIIHDFQPH-----VIVHCAAERRPDVVENQPDAASQ----LNVDASGNLAKEAAAV 120 Query: 122 MIQQQGGSIVNVGSIVGLKG-NSGQ---------SVYSASK 152 G ++ + S G N ++Y +K Sbjct: 121 -----GAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTK 156 >1BXK-A nrPDB Length = 355 Score = 36.2 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 28/182 (15%), Positives = 62/182 (34%), Gaps = 31/182 (17%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE---GAKAAAGDLGGDHLAF-SCDVA 58 + + GG+ IG A+ + + + V+ L + A + AF D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 59 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 ++ F E + + +++ A + + + + TN++G+ +AA Sbjct: 62 DRAELARVFTEHQ-----PDCVMHLAAESHVDRSIDGPA----AFIETNIVGTYTLLEAA 112 Query: 119 MRT---MIQQQGGSI----VNVGSIVG-----------LKGNSGQSVYSASKGGLVGFSR 160 + + + + ++ + G + S YSASK R Sbjct: 113 RAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVR 172 Query: 161 AL 162 A Sbjct: 173 AW 174 >3VPX-A nrPDB Length = 364 Score = 36.2 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 25/64 (39%), Gaps = 3/64 (4%) Query: 8 FGGSRGIG---RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 +G+G A+ + + +G +L + N E + A G + + ++E D+ Sbjct: 175 TVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINEIYSQEADIF 234 Query: 65 NTFE 68 Sbjct: 235 APCA 238 >1LU9-A nrPDB Length = 287 Score = 36.2 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 27/64 (42%), Gaps = 3/64 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G+ +G A L+A +G + + R L+ A+AAA + F +V Sbjct: 120 KKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKR---FKVNVTAAET 176 Query: 63 VQNT 66 + Sbjct: 177 ADDA 180 >4EUF-A nrPDB Length = 418 Score = 36.2 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 25/96 (26%), Gaps = 17/96 (17%) Query: 3 KVCAVFGGSRGIGRA--VAQLMARKGYRLA-------VIARNLEGA--------KAAAGD 45 K + G S G G A ++ R + A K A Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 46 LGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLV 81 G F D + ++ G+++ V Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >2P4H-X nrPDB Length = 322 Score = 35.5 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 41/260 (15%), Positives = 74/260 (28%), Gaps = 63/260 (24%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL------GGDHLAFSCD 56 +VC V GG+ +G + + + GY + R K L F+ D Sbjct: 3 RVC-VTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFNAD 61 Query: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSMLTC 115 ++ E GI + + + + G++ Sbjct: 62 LSNPDSFAAAIEG-------------CVGIFHTASPIDFAVSEPEEIVTKRTVDGALGIL 108 Query: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGN----------------------SGQSVYSASKG 153 KA + + ++ + S + N Y+ SK Sbjct: 109 KACVNSKTVKRF---IYTSSGSAVSFNGKDKDVLDESDWSDVDLLRSVKPFGWNYAVSKT 165 Query: 154 GLVGFSRALAKEVARK-KIRVNV-VAP---GFVHTDMTKDLKEEHL------KKNIPLGR 202 + E + I V + P G D E+ L K+ I + R Sbjct: 166 ----LAEKAVLEFGEQNGIDVVTLILPFIVGRFVCPKLPDSIEKALVLVLGKKEQIGVTR 221 Query: 203 --FGETIEVAHAVVFLLESP 220 +VA A ++LLE+ Sbjct: 222 FHMVHVDDVARAHIYLLENS 241 >1ZDL-A nrPDB Length = 517 Score = 35.5 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 21/50 (42%), Gaps = 1/50 (2%) Query: 6 AVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSC 55 V GG G G A A+ A+ G ++AV + LGG + C Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGC 84 >4EJ6-A nrPDB Length = 370 Score = 34.7 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 31/84 (36%), Gaps = 5/84 (5%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V + GG IG QL G +++ + A ++G + D + V Sbjct: 186 VAILGGGV--IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATA---TVDPSAGDVV 240 Query: 64 QNTFEELEKHLGRVNFLVNAAGIN 87 + + G V+ ++ AG+ Sbjct: 241 EAIAGPVGLVPGGVDVVIECAGVA 264 >5ENV-A nrPDB Length = 347 Score = 34.7 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Query: 5 CAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 A+ G + G+G ++A A+ GYR+ I EG + +GG+ D KE D+ Sbjct: 173 VAISGAAGGLG-SLAVQYAKAMGYRVLGID-GGEGKEELFRSIGGEVFI---DFTKEKDI 227 Query: 64 QNTFEELEK--HLGRVNFLVNAAGINRDGLLVR 94 + G +N V+ A I VR Sbjct: 228 VGAVLKATDGGAHGVINVSVSEAAIEASTRYVR 260 >2HK7-A nrPDB Length = 269 Score = 34.7 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 +K V G G RAV + ++G ++ + R E A A + + +V + Sbjct: 123 EKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKV 181 Query: 62 DV 63 V Sbjct: 182 QV 183 >2GGS-A nrPDB Length = 273 Score = 34.3 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 14/112 (12%), Positives = 38/112 (33%), Gaps = 21/112 (18%) Query: 6 AVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQN 65 + G S +G +++L++ + + + + + ++ G + D+ Sbjct: 4 LITGASGQLGIELSRLLSER-HEVIKVYNS--------SEIQG---GYKLDLTD---FPR 48 Query: 66 TFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 + + K R + ++NAA + V + N +A Sbjct: 49 LEDFIIKK--RPDVIINAAAMTD----VDKCEIEKEKAYKINAEAVRHIVRA 94 >6ACQ-A nrPDB Length = 302 Score = 34.3 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKA 41 M KVC + G+ +G +AQ A KG+ + + E Sbjct: 21 MKKVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDR 59 >3PVZ-A nrPDB Length = 399 Score = 33.9 bits (77), Expect = 0.053, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 66/180 (36%), Gaps = 22/180 (12%) Query: 6 AVFGGSRGIGRAVAQL-MARKGYRLAVIARNLEGAKAAAGD-------LGGDHLAFSCDV 57 V GG+ IG+AV + R +L V+ + D + GD F+ D+ Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFALDI 98 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 ++ K G+ ++++N + + ++ + N+ + T + Sbjct: 99 GSIE-----YDAFIKADGQYDYVLNLSALKHVRS--EKDPFTLMRMIDVNVFNTDKTIQQ 151 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 177 ++ ++ + K + ++ ASK + F ++E+A R VA Sbjct: 152 SIDAGAKKYF-------CVSTDKAANPVNMMGASKRIMEMFLMRKSEEIAISTARFANVA 204 >1MLD-A nrPDB Length = 314 Score = 33.9 bits (77), Expect = 0.055, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 40/121 (33%), Gaps = 17/121 (14%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G S GIG+ ++ L+ + ++ A DL + Sbjct: 2 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLS--------HIETRAT 52 Query: 63 VQNTF--EELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V+ E+L L + +V AG+ R + R +TN A + Sbjct: 53 VKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNATIVATLTAACAQ 106 Query: 121 T 121 Sbjct: 107 H 107 >5INT-A nrPDB Length = 220 Score = 33.9 bits (77), Expect = 0.059, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 34/94 (36%), Gaps = 16/94 (17%) Query: 1 MDKVCAVFGGSRG-IGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVA- 58 +D V + S G +G A+A++ G + +++ G L V Sbjct: 20 IDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS-------------GPTALNPPLHVTT 66 Query: 59 -KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGL 91 + Q+ E + +H V+ ++ A + Sbjct: 67 VQVESAQDMLEAVIQHYQNVDVVIKTAAVADYRP 100 >3PEF-A nrPDB Length = 287 Score = 33.9 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 13 GI-GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDV 57 GI G A+A+ + + G + + R+ E A+ A LG + A C+V Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAA-LGAERAATPCEV 54 >3IP1-A nrPDB Length = 404 Score = 33.9 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 4/64 (6%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 + GG IG A ++ G +++ E + A +LG DH+ D KE+ V+ Sbjct: 217 VVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVI---DPTKENFVE 272 Query: 65 NTFE 68 + Sbjct: 273 AVLD 276 >1O89-A nrPDB Length = 345 Score = 33.9 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 18/44 (40%), Gaps = 1/44 (2%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG 48 V G S G+G L+ + GY++ ++ E LG Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVS-GRESTHEYLKSLGA 213 >1EQ2-A nrPDB Length = 310 Score = 33.9 bits (77), Expect = 0.068, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 51/170 (30%), Gaps = 29/170 (17%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V GG+ IG + + + KG ++ NL+ ++A D + Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVN-------LVDLNIADYMDKE 54 Query: 65 NTFEELE--KHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGS----MLTCKAA 118 + ++ + G V I +G T D + N S + Sbjct: 55 DFLIQIMAGEEFGDVE------AIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLERE 108 Query: 119 MRTMIQQQ----GGSIVNVGS--IVGLKGNSGQSVYSASKGGLVGFSRAL 162 + + GG S I + +VY SK + R + Sbjct: 109 IPFLYASSAATYGGR----TSDFIESREYEKPLNVYGYSKFLFDEYVRQI 154 >2X86-A nrPDB Length = 357 Score = 33.6 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 36/108 (33%), Gaps = 15/108 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 ++ V GG+ IG + + + KG ++ NL+ ++A D Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVN-------LVDLNIADYMD 99 Query: 63 VQNTFEELE--KHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNL 108 ++ ++ + G V I +G T D + N Sbjct: 100 KEDFLIQIMAGEEFGDVE------AIFHEGACSSTTEWDGKYMMDNNY 141 >4K28-A nrPDB Length = 269 Score = 33.6 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 2/54 (3%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKG-YRLAVIARNLEGAKAAAGDLGGDHLAFSC 55 K V G G+G A+A +A G + + + A LG + Sbjct: 126 KRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTV 178 >3OND-A nrPDB Length = 488 Score = 33.6 bits (76), Expect = 0.076, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 3/61 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G +G+ A + + G R+ V + A A + G L DV E D Sbjct: 266 KVAVVAGYGD-VGKGCAAALKQAGARVIVTEIDPICALQATME-GLQVLTLE-DVVSEAD 322 Query: 63 V 63 + Sbjct: 323 I 323 >3VR3-A nrPDB Length = 600 Score = 33.6 bits (76), Expect = 0.082, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 24/63 (38%) Query: 15 GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHL 74 G +A+ GY +A++A + A ++ G D + + E + Sbjct: 317 GITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERS 376 Query: 75 GRV 77 GRV Sbjct: 377 GRV 379 >4WLE-A nrPDB Length = 340 Score = 33.6 bits (76), Expect = 0.082, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 41/121 (33%), Gaps = 17/121 (14%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G S GIG+ ++ L+ + ++ A DL + + Sbjct: 28 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLS--------HIETKAA 78 Query: 63 VQNTF--EELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMR 120 V+ E+L L + +V AG+ R + R +TN A + Sbjct: 79 VKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNATIVATLTAACAQ 132 Query: 121 T 121 Sbjct: 133 H 133 >6C6P-A nrPDB Length = 458 Score = 33.2 bits (75), Expect = 0.092, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 30/70 (42%), Gaps = 3/70 (4%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSC-DVAKEHD 62 V V G+ +G A+A +++R G ++ VI R+L+ G+ D+ Sbjct: 10 VIIV--GAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLGDT 67 Query: 63 VQNTFEELEK 72 V+ ++ Sbjct: 68 VEGLDAQVVN 77 >3LK7-A nrPDB Length = 451 Score = 33.2 bits (75), Expect = 0.093, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSC 55 +K V G +R G A A+L+A+ G + V A L + + C Sbjct: 9 NKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVC 61 >2EXX-A nrPDB Length = 306 Score = 33.2 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKG-YRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 K+ VFGG+ G +VA+ + G +++ V+ RN A L G D + Sbjct: 12 KLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQG-AEVVQGDQDDQV 70 Query: 62 DVQNTFEELEKHL 74 ++ Sbjct: 71 IMELALNGAYATF 83 >4J6F-A nrPDB Length = 382 Score = 33.2 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 23/74 (31%), Gaps = 21/74 (28%) Query: 4 VCAVFGGSRGIGRAVAQLMARK--------------------GYRLAVIARNLEGAKAAA 43 V G S G+G A+ +AR G + V + A+A Sbjct: 209 TVLVTGASGGVGSAI-IQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAEAVE 267 Query: 44 GDLGGDHLAFSCDV 57 GG + D+ Sbjct: 268 AASGGRPIDVVADL 281 >4B4O-A nrPDB Length = 298 Score = 32.8 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 39/117 (33%), Gaps = 23/117 (19%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V GG+ IG A+ QL+ +G+ + +++R + +L L Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLP------------ 50 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121 + VN AG N L R L + L + L KA + Sbjct: 51 -----------SCDAAVNLAGENILNPLRRWNETFQKEVLGSRLETTQLLAKAITKA 96 >2C54-A nrPDB Length = 379 Score = 32.8 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 35/112 (31%), Gaps = 13/112 (11%) Query: 7 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 + G I +A+ + +G+ + + D+ D D+ Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKN--EHMTEDMFCDEFHLV-DL-------RV 83 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E K V+ + N A D + + ++ N + S +AA Sbjct: 84 MENCLKVTEGVDHVFNLAA---DMGGMGFIQSNHSVIMYNNTMISFNMIEAA 132 >1DB3-A nrPDB Length = 372 Score = 32.8 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 26/77 (33%), Gaps = 8/77 (10%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR-----NLEGAKAAAGD---LGGDHLAF 53 KV + G + G +A+ + KGY + I R N E D Sbjct: 1 SKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLH 60 Query: 54 SCDVAKEHDVQNTFEEL 70 D++ ++ E+ Sbjct: 61 YGDLSDTSNLTRILREV 77 >4KDR-A nrPDB Length = 223 Score = 32.8 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K G GI +A+ MAR+G + + E + L D Sbjct: 64 KKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQ--VAKLHALESGIQVD-----Y 113 Query: 63 VQNTFEE-LEKHLGRVNFL 80 VQ T EE KH G+ + + Sbjct: 114 VQETVEEHAAKHAGQYDVV 132 >5U9C-A nrPDB Length = 292 Score = 32.4 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 3/67 (4%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR---NLEGAKAAAGDLGGDHLAFSCDV 57 M + + GG+ +G V + Y + V R NL +A + + Sbjct: 4 MKRKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHF 63 Query: 58 AKEHDVQ 64 A E DV Sbjct: 64 AAETDVD 70 >4KDC-A nrPDB Length = 246 Score = 32.4 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K G GI +A+ MAR+G + + E + L D Sbjct: 64 KKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQ--VAKLHALESGIQVD-----Y 113 Query: 63 VQNTFEE-LEKHLGRVNFL 80 VQ T EE KH G+ + + Sbjct: 114 VQETVEEHAAKHAGQYDVV 132 >1ML4-A nrPDB Length = 308 Score = 32.4 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 25/56 (44%), Gaps = 2/56 (3%) Query: 27 YRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFE--ELEKHLGRVNFL 80 + VI EGA A ++ + + D + +H Q + ++K GR++ L Sbjct: 101 CDVIVIRHPKEGAARLAAEVAEVPVINAGDGSNQHPTQTLLDLYTIKKEFGRIDGL 156 >4Z6K-A nrPDB Length = 346 Score = 32.4 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 41/102 (40%), Gaps = 14/102 (13%) Query: 16 RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHLG 75 A A+ + G ++ V A+N + A+ ++GG H A V+ F++ L Sbjct: 201 LAFAKKL---GAKVTVNAKNTDPAEYLQKEIGGAHGALVTAVS-----AKAFDQALSMLR 252 Query: 76 RVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSMLTCK 116 R LV G+ V + L+ + GS++ + Sbjct: 253 RGGTLVCN-GLPPGDFPVSI----FDTVLNGITIRGSIVGTR 289 >2GAS-A nrPDB Length = 307 Score = 32.4 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 30/88 (34%), Gaps = 14/88 (15%) Query: 5 CAVFGGSRGIGRAVAQLMARKG---YRLA---VIARNLEGAKAAAGDLGGDHLAF-SCDV 57 + G + IGR + + G Y L + A N E + + + D+ Sbjct: 5 ILILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLGVILLEGDI 64 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAG 85 + ++ V+ ++ AAG Sbjct: 65 NDHETLVKAIKQ-------VDIVICAAG 85 >3BIC-A nrPDB Length = 762 Score = 32.4 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 31/107 (28%), Gaps = 13/107 (12%) Query: 9 GGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFE 68 G RG + +A A G+ + + + A + D A + Sbjct: 616 GHDRG-AKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGV-STLAAGHKTLVP 673 Query: 69 ELEKHL---GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112 EL K L GR + LV G+ +D + Sbjct: 674 ELIKELNSLGRPDILVMCGGV--------IPPQDYEFLFEVGVSNVF 712 >1QYD-A nrPDB Length = 313 Score = 32.4 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 19/104 (18%) Query: 1 MDKV--CAVFGGSRGIGRAVAQLMARKGYRLAVIAR-----NLEGAKAAA--GDLGGDHL 51 MDK + GG+ IG+ + G+ V+ R N++ + LG + Sbjct: 1 MDKKSRVLIVGGTGYIGKRIVNASISLGHPTYVLFRPEVVSNIDKVQMLLYFKQLGAKLI 60 Query: 52 AFSCDVAKEHDVQNTFEELEKHLGRVNFLVNA-AGINRDGLLVR 94 S D D Q + L++ V+ +++A AG ++ Sbjct: 61 EASLD-----DHQRLVDALKQ----VDVVISALAGGVLSHHILE 95 >1JPH-A nrPDB Length = 388 Score = 32.0 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 30/83 (36%), Gaps = 9/83 (10%) Query: 20 QLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDV------AKEHDVQNTFEELEKH 73 + +A+ GY + + + K A + G + ++ A E ++ +++ Sbjct: 291 EELAQAGYEVVGLDWTVAPKK--ARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDD 348 Query: 74 LGRVNFLVN-AAGINRDGLLVRT 95 G ++ N G+ D Sbjct: 349 FGPHRYIANLGHGLYPDMDPEHV 371 >6BMQ-A nrPDB Length = 523 Score = 32.0 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%) Query: 24 RKGYRLAVIARNLEGAKAAAGDLGGDHLAFS 54 KG ++ + R E A A +GG L+ + Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKALSLT 415 >4WOK-A nrPDB Length = 336 Score = 32.0 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 30/139 (21%), Positives = 44/139 (31%), Gaps = 18/139 (12%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V GG+ IG A+L+A +GY V NL +A G D+ + + Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVVYD-NLSTGHQSAVRWGD---FVEGDILDQARLV 69 Query: 65 NTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 T E+ +++ A G ED N+ G+ A T Q Sbjct: 70 ETMEKYAPV-----AVIHFAASAYVG----ESVEDPAKYYRNNVGGTQSLLDACRLTRTQ 120 Query: 125 QQGGSIVNVGSIVGLKGNS 143 V S G Sbjct: 121 N-----VIFSSSCATYGVP 134 >3DMF-A nrPDB Length = 381 Score = 32.0 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 18/126 (14%), Positives = 41/126 (32%), Gaps = 15/126 (11%) Query: 9 GGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFE 68 G G A+ +AR G + + +L + L + L K + + + Sbjct: 241 GAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANAL-------KAQALHSDVD 290 Query: 69 ELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLL--GSMLTCK---AAMRTMI 123 E R + +V + G ++ + V+ L G ++ Sbjct: 291 EALTEEARFDIIVTNPPFHVGGAVILDVAQAFVNVAAARLRPGGVFFLVSNPFLKYEPLL 350 Query: 124 QQQGGS 129 +++ G+ Sbjct: 351 EEKFGA 356 >6G2J-P nrPDB Length = 377 Score = 32.0 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 37/109 (33%), Gaps = 19/109 (17%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIAR----NLEGAKAAAGDLGGDHLAFSCDVAK 59 V VFG + +GR V + R G ++ + R ++ + GDLG D Sbjct: 55 VATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLR-LMGDLG-QLTFLEWDARD 112 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNL 108 + ++ + + IN G T+ D N+ Sbjct: 113 KDSIRKAVQH------------SNVVINLIGREWETRNFDFEDVF-VNI 148 >3R9I-A nrPDB Length = 260 Score = 31.6 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%), Gaps = 5/38 (13%) Query: 1 MDKVCAVFGGSRGIGR-----AVAQLMARKGYRLAVIA 33 M ++ V G G+G+ A+A +A+KG + VI Sbjct: 1 MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVID 38 >1JAY-A nrPDB Length = 212 Score = 31.6 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 13/68 (19%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE------------GAKAAAGDLGGDH 50 +V + GG+ +G+ +A +A G+ + V +R E A+ + + Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNED 60 Query: 51 LAFSCDVA 58 A +CD+A Sbjct: 61 AAEACDIA 68 >3WMX-A nrPDB Length = 358 Score = 31.6 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 32/198 (16%), Positives = 60/198 (30%), Gaps = 43/198 (21%) Query: 5 CAVFGGSRGIGRAVAQLMARK-GYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 + G + IG +A +A + G + + + G H+ + ++ D Sbjct: 28 ILIVGANGQIGSELALALAERYGRTNVITSDVVPT---------GRHVHLTHEMLNATD- 77 Query: 64 QNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMI 123 + + + G + AA ++ G K + N+ + + A Sbjct: 78 RGELATVVERHGITQVYLLAAALSATG----EKAPQW--AWNLNMTSLLNVLELA----- 126 Query: 124 QQQGG--SIVNVGSIVGLKG------------NSGQSVYSASKGGLVGFSRALAKEVARK 169 +Q G + SI +VY SK G+ R A Sbjct: 127 -RQTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWCRWY---HANH 182 Query: 170 KIRVNVVA-PGFV--HTD 184 + V V PG + T Sbjct: 183 GVDVRSVRYPGLISHKTP 200 >1C0L-A nrPDB Length = 363 Score = 31.6 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNL 36 K V G IG + A ++ARKGY + ++AR+L Sbjct: 7 KRVVVLGSGV-IGLSSALILARKGYSVHILARDL 39 >4N18-A nrPDB Length = 332 Score = 31.6 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 26/70 (37%), Gaps = 21/70 (30%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKH 73 IG +A +AR GYR++ +R+ + G EE H Sbjct: 167 IGGYIADQLARLGYRVSGWSRSEKQLAGVTCYRG--------------------EEALDH 206 Query: 74 L-GRVNFLVN 82 G ++ L+N Sbjct: 207 FLGSLDGLIN 216 >4UUP-A nrPDB Length = 341 Score = 31.6 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 34/103 (33%), Gaps = 19/103 (18%) Query: 5 CAVFGGSRGIGRAVAQLMARKGY----RLAVIARNLEGAKAAAG----DLGGDHLAFSCD 56 + G + IG A+A +A+ ++ + + A A +L Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 57 VAKEHDVQNTFEELEKHL-----------GRVNFLVNAAGINR 88 V D + F++++ R + L AGI + Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFK 109 >3DQQ-A nrPDB Length = 421 Score = 31.6 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 53/174 (30%), Gaps = 30/174 (17%) Query: 6 AVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQN 65 V GGS G+ +A+ A+ G + A++A L G + S + Sbjct: 219 LVTGGS-GLAMGLARQWAKHG---------VSQARSAGYPLSGRAVVLSG--SCSQMTNQ 266 Query: 66 TFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQ 125 +H RD + R + + L +L+ + + MI Sbjct: 267 QVAFYRQH-----------APTRDVDVARCLSSETREAYAEALAQWVLSQDSELAPMISA 315 Query: 126 QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179 S L Q + + + LA +A I +VA G Sbjct: 316 -------TASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGG 362 >3F6S-A nrPDB Length = 148 Score = 31.2 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 1 MDKVCAVFGGSRGIGRAVAQLM----ARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCD 56 M KV VFG S G ++AQ + A G+ + ++ A+ A S Sbjct: 1 MSKVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLADGYDAVLFGCSAW 60 Query: 57 VAKEHDVQNTFEELEKHLGRV 77 ++ ++Q+ F L + R+ Sbjct: 61 GMEDLEMQDDFLSLFEEFDRI 81 >3K6J-A nrPDB Length = 460 Score = 30.9 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS 54 ++ V + GG+ +G+A+A G ++ RN + K + +F Sbjct: 54 VNSVAIIGGGT--MGKAMAICFGLAGIETFLVVRNEQRCKQELEVMYAREKSFK 105 >1HE4-A nrPDB Length = 206 Score = 30.9 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 22/66 (33%), Gaps = 3/66 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K A+FG + G + GY + V+ R+ + DV + D Sbjct: 4 KKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRL---PSEGPRPAHVVVGDVLQAAD 60 Query: 63 VQNTFE 68 V T Sbjct: 61 VDKTVA 66 >4BKP-A nrPDB Length = 336 Score = 30.9 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 37/107 (34%), Gaps = 26/107 (24%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS---CDVAKEH 61 V GGS +G+A+ Q + G L G D + S D+ Sbjct: 25 ILVTGGSGLVGKAI-QKVVADGAGL----------------PGEDWVFVSSKDADLTDTA 67 Query: 62 DVQNTFEELEKHLGRVNFLVN-AAGINRDGLLVRTKTEDMVSQLHTN 107 + FE+++ +++ AA + ++ + +H N Sbjct: 68 QTRALFEKVQPTH-----VIHLAAMVGGLFRNIKYNLDFWRKNVHMN 109 >2VN8-A nrPDB Length = 375 Score = 30.9 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 13/113 (11%) Query: 3 KVCAVFGGSRGIG-RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 K + G S G+G A+ + A + AV +++ LG D DV Sbjct: 185 KRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDAS---ELVRKLGAD------DVIDYK 235 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLT 114 + EE K L +F+++ G + + + + L+ L Sbjct: 236 S--GSVEEQLKSLKPFDFILDNVGGSTETWAPDF-LKKWSGATYVTLVTPFLL 285 >4J90-A nrPDB Length = 222 Score = 30.9 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 13 GIGR---AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 G+GR ++ + + R G+ + + N E A A A + +E+++ Sbjct: 13 GLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASY---ATHAVIANATEENEL 63 >2EER-A nrPDB Length = 347 Score = 30.5 bits (68), Expect = 0.59, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 16/44 (36%), Gaps = 1/44 (2%) Query: 2 DKVCAVFGGSRGIGR-AVAQLMARKGYRLAVIARNLEGAKAAAG 44 K V G G+G A+ A G + + E +AA Sbjct: 171 SKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKR 214 >5VXO-A nrPDB Length = 325 Score = 30.5 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 2/48 (4%) Query: 164 KEVARKK--IRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEV 209 ++ + +RVN V+ G D+ L+ L ++ L + E+ Sbjct: 74 IDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEI 121 >3MFY-A nrPDB Length = 588 Score = 30.5 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%) Query: 15 GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHL 74 G +A+ GY +A++A + A ++ G + + + E + Sbjct: 312 GITIAEYFRDMGYDVALMADSTSRWAEALREISGRLEEMPGEEGYPAYLASKLAEFYERA 371 Query: 75 GRV 77 GRV Sbjct: 372 GRV 374 >1U3W-A nrPDB Length = 374 Score = 30.1 bits (67), Expect = 0.76, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 32/87 (36%), Gaps = 17/87 (19%) Query: 3 KVCAVFGGS-------RGIGRAVAQLMARKG-YRLAVIARNLEGAKAAAGDLGGDHLAFS 54 KV V GS G+G +V G R+ + N + A A +LG Sbjct: 185 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKF-AKAKELGATECI-- 241 Query: 55 CDVAKEHDVQNTFEELEKHL--GRVNF 79 D + +E+ K + G V+F Sbjct: 242 ----NPQDYKKPIQEVLKEMTDGGVDF 264 >3NJ4-A nrPDB Length = 435 Score = 30.1 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 19/43 (44%), Gaps = 1/43 (2%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD 45 KV V G +G+ AQ + G R+ + + A AA + Sbjct: 217 KVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAME 258 >5BUT-A nrPDB Length = 288 Score = 30.1 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 13 GIGR---AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 G+GR ++ + + R G+ + + N E A A A + +E+++ Sbjct: 13 GLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY---ATHAVIANATEENEL 63 Score = 30.1 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 13 GIGR---AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 G+GR ++ + + R G+ + + N E A A A + +E+++ Sbjct: 155 GLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY---ATHAVIANATEENEL 205 >2V6G-A nrPDB Length = 364 Score = 30.1 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 9/69 (13%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKG-----YRLAVIARNLEGAKAAAGDLGGDHLAFSCD 56 V + G + IG ++A+++ +++ +AR A CD Sbjct: 1 SSVALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRT----RPAWHEDNPINYVQCD 56 Query: 57 VAKEHDVQN 65 ++ D Q Sbjct: 57 ISDPDDSQA 65 >5BN5-A nrPDB Length = 570 Score = 30.1 bits (67), Expect = 0.96, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 22/67 (32%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKH 73 +G + + +GY + V A + A ++ + + E + Sbjct: 300 LGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYER 359 Query: 74 LGRVNFL 80 GRV L Sbjct: 360 SGRVRTL 366 >6MVR-A nrPDB Length = 767 Score = 29.7 bits (66), Expect = 1.00, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 20/86 (23%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAK- 59 +DKV G + +GR + + A G KA + +LGG CD A Sbjct: 233 VDKVAF-TGSTA-VGRRIREATAGTG-------------KALSLELGGKGPYVVCDDADI 277 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAG 85 + V+ + + + G+ V AG Sbjct: 278 DSAVEGLVDAIWFNQGQ----VCCAG 299 >2HMT-A nrPDB Length = 144 Score = 29.7 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 17/35 (48%), Gaps = 3/35 (8%) Query: 13 GIGR---AVAQLMARKGYRLAVIARNLEGAKAAAG 44 G+GR ++ + + R G+ + + N E A A Sbjct: 13 GLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYAS 47 >4GBJ-A nrPDB Length = 297 Score = 29.7 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 13/75 (17%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCD-----------VAKEHD 62 +G +A+++ GY L V R A+ LG + + D +A + Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKAEPL-TKLGATVVENAIDAITPGGIVFSVLADDAA 74 Query: 63 VQNTFE-ELEKHLGR 76 V+ F EL + LG+ Sbjct: 75 VEELFSMELVEKLGK 89 >3DOJ-A nrPDB Length = 310 Score = 29.7 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 37/100 (37%), Gaps = 8/100 (8%) Query: 13 GI-GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELE 71 GI G+A++ + + G+++ V R L + G +V K+ + T L Sbjct: 30 GIMGKAMSMNLLKNGFKVTVWNRTLSKCDELV-EHGASVCESPAEVIKK--CKYTIAMLS 86 Query: 72 KHLGRVNFLVNAAG----INRDGLLVRTKTEDMVSQLHTN 107 ++ + + G I + T D + L N Sbjct: 87 DPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKIN 126 >6BI4-A nrPDB Length = 346 Score = 29.7 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 28/173 (16%), Positives = 57/173 (32%), Gaps = 26/173 (15%) Query: 5 CAVFGGSRGIGRAVAQLMARK-------GYRLAVIARNLEGAKAAAGDLGGDHLAFSCDV 57 V GG+ IG M + + + NL K+ ++ ++ Sbjct: 27 ILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHP--NYYFVKGEI 84 Query: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 117 +++ +E + V +VN A + V E+ + TN++G++ + Sbjct: 85 QNGELLEHVIKERD-----VQVIVNFAAESH----VDRSIENPIPFYDTNVIGTVTLLEL 135 Query: 118 AMRTM--------IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRAL 162 + + GS+ G + S YS+SK + A Sbjct: 136 VKKYPHIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKASADMIALAY 188 >3PII-A nrPDB Length = 339 Score = 29.7 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 40/107 (37%), Gaps = 17/107 (15%) Query: 14 IG---RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEEL 70 IG +A+ + G L V + AK +GG H A V+K Q+ + + Sbjct: 196 IGDEKLELAKEL---GADLVVNPLKEDAAKFMKEKVGGVHAAVVTAVSKPA-FQSAYNSI 251 Query: 71 EKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH-TNLLGSMLTCK 116 + G LV G+ + L+ ++GS++ + Sbjct: 252 RR--GGACVLV---GL----PPEEMPIPIFDTVLNGIKIIGSIVGTR 289 >2CF5-A nrPDB Length = 357 Score = 29.7 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKH 73 +G +A+ G+ + VI+ + + + A DLG D D AK ++ ++ + + Sbjct: 195 MGVKIAKA---MGHHVTVISSSNKKREEALQDLGADDYVIGSDQAKMSELADSLDYVIDT 251 >3X2F-A nrPDB Length = 411 Score = 29.3 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 38/110 (34%), Gaps = 12/110 (10%) Query: 18 VAQLMARKGYRLAVIARN-LEGAKAAAGDLGGDHLAFSCDVAKEHDV--QNTFEELEKHL 74 +A +++ G ++ + N L A L + + + +N + L++ Sbjct: 50 LAITLSKLGAKVVITGSNPLSTQDDVAEALRSKGITVYARRTHDESIYRENLMKVLDE-- 107 Query: 75 GRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQ 124 R +F+ I+ G L + L NL G +R + Sbjct: 108 -RPDFI-----IDDGGDLTVISHTEREEVLE-NLKGVSEETTTGVRRLKA 150 Score = 28.5 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 43/135 (31%), Gaps = 26/135 (19%) Query: 15 GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHL 74 GR +A A G R+ V ++ KA + G V + + + Sbjct: 209 GRGIALRAAGLGARVIVTE--VDPVKAVEAIMDG------FTVMPMKEAVKIADFVITAS 260 Query: 75 GRVNFL-------------VNAAGINRDGLLVRTKTEDMVSQLHT--NLLGSMLTCKAAM 119 G + L + AG + VR E V + N+ G L + Sbjct: 261 GNTDVLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEIAVEKFEARPNVTGYTLENGKTV 320 Query: 120 RTMIQQQGGSIVNVG 134 + + G +VN+ Sbjct: 321 FLLAE---GRLVNLA 332 >5JXW-A nrPDB Length = 498 Score = 29.3 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G +G+ AQ ++ G R+ V ++ A + G ++ DV E D Sbjct: 272 KKIVVLGYGE-VGKGCAQGLSGVGARVIVTE--IDPICALQASMEGYQVSVLEDVVSEAD 328 Query: 63 V 63 + Sbjct: 329 I 329 >5UZH-A nrPDB Length = 345 Score = 29.3 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 26/78 (33%), Gaps = 8/78 (10%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIAR--------NLEGAKAAAGDLGGDHLAF 53 KV + G + G +A+ + KGY + I R +E Sbjct: 1 SKVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLL 60 Query: 54 SCDVAKEHDVQNTFEELE 71 D+ ++ + +++ Sbjct: 61 YGDLTDTGNLISIIAKIK 78 >5GXF-A nrPDB Length = 330 Score = 29.3 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 16/36 (44%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAK 40 V G + G+G ++A GY +A + E A Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >4E0B-A nrPDB Length = 313 Score = 29.3 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%), Gaps = 4/34 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMAR---KGYRLAVIA 33 KV + G + GIG+A+A L+ G LA+ Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYD 37 >4AP9-A nrPDB Length = 201 Score = 29.3 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 20/37 (54%) Query: 16 RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA 52 R + + + KG+++ +I+ + E +LG + +A Sbjct: 85 RELVETLREKGFKVVLISGSFEEVLEPFKELGDEFMA 121 >7REQ-A nrPDB Length = 727 Score = 29.3 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 32/99 (32%), Gaps = 3/99 (3%) Query: 9 GGSRGIGRAVAQLMARKGYRLAV--IARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 66 G RG + +A A G+ + V + + E A + + S + Sbjct: 608 GHDRGQ-KVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPA 666 Query: 67 FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH 105 + LGR + L+ G+ + + + V Sbjct: 667 LRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYT 705 >1YXY-A nrPDB Length = 234 Score = 29.3 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 7/57 (12%) Query: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176 + M Q +GG IV + G+ +YS + GG++ A+E IR N V Sbjct: 9 KLMEQLKGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >6BII-A nrPDB Length = 333 Score = 28.9 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 43/120 (35%), Gaps = 16/120 (13%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G R IG+A+A+ G R+ AR+ + A +LG + + + Sbjct: 151 KTIGIVGFGR-IGQAIAKRAKGFGMRILYTARSRKP--EAEKELGAEFKPLEELLRESDF 207 Query: 63 VQNTFEELEKHLGRVN-----------FLVNAA--GINRDGLLVRTKTEDMVSQLHTNLL 109 V ++ +N LVN A + L+R E ++ ++ Sbjct: 208 VVLAVPLTKETYHMINEERLRLMKPTAVLVNVARGKVVDTKALIRALKEGWIAAAGLDVF 267 >3H0K-A nrPDB Length = 178 Score = 28.9 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 24/53 (45%), Gaps = 2/53 (3%) Query: 3 KVCAVFGGSRGIGR-AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS 54 KV + G G G+ A+L+ +G ++ V++ + + G + F+ Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFA 52 >5NUE-A nrPDB Length = 332 Score = 28.9 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 28/118 (23%), Positives = 40/118 (33%), Gaps = 12/118 (10%) Query: 5 CAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 V G + IG A+ ++AR G VI L+ AA G Sbjct: 8 VLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLK 67 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119 V T + +E G VN V G R + R + N+ S+ +AA Sbjct: 68 GVVATTDAVEGCTG-VNVAVMVGGFPRKEGMER------KDVMSKNV--SIYKSQAAA 116 >4RQU-A nrPDB Length = 375 Score = 28.9 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 8/77 (10%) Query: 1 MDKVCAVF-GGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA-GDLGGDHLAFSCDVA 58 +DKVC V G S G+G + +KG +A+ G AA + G D Sbjct: 165 LDKVCIVSCGLSTGLGATLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFN 224 Query: 59 KEHDVQNTFEELEKHLG 75 + F++ K G Sbjct: 225 SKR-----FDQA-KEFG 235 >5GUP-L nrPDB Length = 377 Score = 28.9 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 32/103 (31%), Gaps = 14/103 (13%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEH 61 V VFG + +GR V + R G ++ V R +G G + + + Sbjct: 55 VATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFMEWNGKDKD 114 Query: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQL 104 ++ E + IN G TK D Sbjct: 115 SIRKVVEH------------SNVVINLVGREWETKNFDFEDVF 145 >1VPD-A nrPDB Length = 299 Score = 28.9 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 6/51 (11%) Query: 13 GI-GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLG-----GDHLAFSCDV 57 GI G+ +++ + + GY L V RN E +A CDV Sbjct: 14 GIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDV 64 >3RI6-A nrPDB Length = 430 Score = 28.5 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 25/80 (31%), Gaps = 16/80 (20%) Query: 8 FGG------SRGIGRAVAQL---MARKGYRLAVIAR----NLEGAKAAAGDLGGDHLAFS 54 G G+ A++ +AR G + R L + G + Sbjct: 95 TGALGVLALGSGM-AAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFV- 152 Query: 55 CDVAKEHDVQNTFEELEKHL 74 DV V++ +E K L Sbjct: 153 -DVMDSLAVEHACDETTKLL 171 >6C55-A nrPDB Length = 340 Score = 28.5 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 6/59 (10%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI---ARNLEGAKAAAGDLGGDHLAF-SCDV 57 K+ V G G A AQ + GY + + R+ + AK D+ A DV Sbjct: 19 KIAVV--GYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADV 75 >4W5U-B nrPDB Length = 408 Score = 28.5 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 22/74 (29%), Gaps = 13/74 (17%) Query: 49 DHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTE---------- 98 + +CD + +N L G + LV A + DG Sbjct: 186 NACGLTCDSSGPDAFRNLMAALRSTFG--DELV-TAAVTADGTPGGKIEATDYAGAAQYV 242 Query: 99 DMVSQLHTNLLGSM 112 D + + + G+ Sbjct: 243 DWYNVMTYDFFGAW 256 >6DEB-A nrPDB Length = 285 Score = 28.5 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 15/30 (50%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVI 32 K + G S +GR +A ++ G ++V Sbjct: 161 KDAVIIGASNIVGRPMATMLLNAGATVSVC 190 >5U5G-A nrPDB Length = 295 Score = 28.5 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD 45 M++V G R +G+A+ + + + V R+ E A Sbjct: 1 MNRVVGFIGLGR-MGQAICRRLLASQMPVHVHNRSREKADDLIRQ 44 >4YUC-A nrPDB Length = 335 Score = 28.2 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 22/168 (13%), Positives = 51/168 (30%), Gaps = 28/168 (16%) Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAG-----INRDGLLVRTKT---EDMVSQLHTN--LL 109 + + L ++ ++NA+G + G LV+ + V + N L Sbjct: 63 AEAAKEAVRDAGLKLEDIDLIINASGSPEQAVPDGGPLVQRELGLGRSGVPSITVNASCL 122 Query: 110 GSMLTCKAAMRTMIQQQGGSIVNVGSIVG-----LKGNSGQSVYS-ASKGGLVGFSRALA 163 + A + ++ I+ V S + + +++ A+ +V Sbjct: 123 SFFVALDVAANYLNMRRYKRILIVSSDISSVALDFRKPENFTLFGDAAAAAVVTL----- 177 Query: 164 KEVARKKIRVNVVAPGFVHT---DMTKDLKEEHLKKNIPLGRFGETIE 208 E K + + V T + + P G+ + Sbjct: 178 PEPGEK----SCIHASQVRTYGYGAEFSMVPGGGSRRHPNGKNTTPED 221 >1ZCJ-A nrPDB Length = 463 Score = 28.2 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 14/31 (45%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAG 44 +GR +A AR G + + + + AA Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKK 78 >3N58-A nrPDB Length = 464 Score = 28.2 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 9/78 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G +G+ AQ +A G R+ V + A AA D G + + D Sbjct: 248 KVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAAMD-GFEVVTL-------DD 298 Query: 63 VQNTFEELEKHLGRVNFL 80 +T + + G + + Sbjct: 299 AASTADIVVTTTGNKDVI 316 >2RIR-A nrPDB Length = 300 Score = 28.2 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 18/73 (24%) Query: 13 GIGRA---VAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEE 69 G+GR +A+ A G + V AR+ A ++G + F D E Sbjct: 164 GLGRTGMTIARTFAALGANVKVGARSSAHL-ARITEMG--LVPFHTD------------E 208 Query: 70 LEKHLGRVNFLVN 82 L++H+ ++ +N Sbjct: 209 LKEHVKDIDICIN 221 >1LLU-A nrPDB Length = 342 Score = 28.2 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 19/46 (41%), Gaps = 3/46 (6%) Query: 16 RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 +A+ + G L V AR + +A D+GG H V+ Sbjct: 207 LELARKL---GASLTVNARQEDPVEAIQRDIGGAHGVLVTAVSNSA 249 >3S2F-A nrPDB Length = 340 Score = 28.2 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 20/41 (48%), Gaps = 3/41 (7%) Query: 18 VAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVA 58 +A+ + G +AV AR+ + A ++GG H V+ Sbjct: 205 LARRL---GAEVAVNARDTDPAAWLQKEIGGAHGVLVTAVS 242 >5VM2-A nrPDB Length = 347 Score = 28.2 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 28/83 (33%), Gaps = 6/83 (7%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K + G IG Q G + LE A A LG + AKE Sbjct: 170 KKIIILGAGC-IGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGA---TVVINGAKEDT 225 Query: 63 VQNTFEELEKHLGRVNFLVNAAG 85 + ++ + +G + + AG Sbjct: 226 IAR-CQQFTEDMGA-DIVFETAG 246 >5LBA-B nrPDB Length = 445 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 23/53 (43%), Gaps = 5/53 (9%) Query: 147 VYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIP 199 VY ++ LA E++ + + G ++ T ++ + +++ +P Sbjct: 256 VYCRTREACEQ----LAIELSCRGVNAKAYHAGLKASERT-LVQNDWMEEKVP 303 >5LB8-A nrPDB Length = 518 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 23/53 (43%), Gaps = 5/53 (9%) Query: 147 VYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIP 199 VY ++ LA E++ + + G ++ T ++ + +++ +P Sbjct: 256 VYCRTREACEQ----LAIELSCRGVNAKAYHAGLKASERT-LVQNDWMEEKVP 303 >1NHQ-A nrPDB Length = 447 Score = 28.2 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%), Gaps = 2/33 (6%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIA 33 ++ V + GS IG A+ A+ G ++ VI Sbjct: 149 VNNVVVI--GSGYIGIEAAEAFAKAGKKVTVID 179 >3H9U-A nrPDB Length = 436 Score = 27.8 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 10/90 (11%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G +G+ A + G R+ V + A AA + G L DV +E Sbjct: 212 KTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAME-GYQVLLVE-DVVEEAH 268 Query: 63 V---QNTFEELE--KHLGRV--NFLVNAAG 85 + +++ +H R+ + +V G Sbjct: 269 IFVTTTGNDDIITSEHFPRMRDDAIVCNIG 298 >5L6F-A nrPDB Length = 497 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 20/67 (29%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 V S + A K ++ V ARN K A +AK V Sbjct: 11 TAVVSAASSPHAKRAAIDECLKNAKVPVTARNSTEWKTDASPFNDRLPYTPAAIAKPATV 70 Query: 64 QNTFEEL 70 ++ + Sbjct: 71 EHIQAAV 77 >3ZWA-A nrPDB Length = 742 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 14/31 (45%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAG 44 +GR +A AR G + + + + AA Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKK 357 >3ZU2-A nrPDB Length = 422 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 34/96 (35%), Gaps = 18/96 (18%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRL----AVIARNLEGAK-------------AAAGD 45 K V G S G G A A++ A G R E K A Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 46 LGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLV 81 G + + D + Q T + +++ LG+V+ ++ Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVI 159 >2QYS-A nrPDB Length = 318 Score = 27.8 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 30/83 (36%), Gaps = 6/83 (7%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 60 M +FGG+ IG + + + G+ V R + E Sbjct: 10 MKSKILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLGAIIVKGELDE 69 Query: 61 HDVQNTFEELEKHLGRVNFLVNA 83 H E+L + + +V+ +++A Sbjct: 70 H------EKLVELMKKVDVVISA 86 >3TWO-A nrPDB Length = 348 Score = 27.8 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 24/74 (32%), Gaps = 13/74 (17%) Query: 7 VFGGSR-------GIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAK 59 V G++ G+G + G ++V ARN E K A +G H Sbjct: 174 VTKGTKVGVAGFGGLGSMAVKYAVAMGAEVSVFARN-EHKKQDALSMGVKHFY-----TD 227 Query: 60 EHDVQNTFEELEKH 73 + + + Sbjct: 228 PKQCKEELDFIIST 241 >2X3N-A nrPDB Length = 399 Score = 27.8 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 19/79 (24%) Query: 5 CAVFGGSRGIGRAV-AQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 + G GIG A+ A L+ R+G+R+ V+ E A+ G D+ K + Sbjct: 9 VLINGC--GIGGAMLAYLLGRQGHRVVVV----EQARRERAING-------ADLLKPAGI 55 Query: 64 Q-----NTFEELEKHLGRV 77 + E+ + GRV Sbjct: 56 RVVEAAGLLAEVTRRGGRV 74 >1YB5-A nrPDB Length = 351 Score = 27.8 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 33/79 (41%), Gaps = 10/79 (12%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 V G S G+G A Q+ G ++ A EG + G + +V Sbjct: 174 VLVHGASGGVGLAACQIARAYGLKILGTAGTEEG-QKIVLQNGAHEVFNHREV------- 225 Query: 65 NTFEELEKHLG--RVNFLV 81 N ++++K++G ++ ++ Sbjct: 226 NYIDKIKKYVGEKGIDIII 244 >4XRR-A nrPDB Length = 456 Score = 27.8 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 12/95 (12%), Positives = 26/95 (27%), Gaps = 2/95 (2%) Query: 6 AVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAA-AGDLGGDHLAFSCDVAKEHDVQ 64 V G+ +G +A +A +G + + + AG + V Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAATG 77 Query: 65 NTFEELE-KHLGRVNFLVNAAGINRDGLLVRTKTE 98 +G + ++ G D + Sbjct: 78 RLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQ 112 >3NT2-A nrPDB Length = 344 Score = 27.8 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 23/71 (32%), Gaps = 7/71 (9%) Query: 8 FGGSRGIGRAVAQLMARK--GYR-LAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQ 64 G IG+ + K G +AV N E A+ + + D + D + Sbjct: 10 TGA---IGKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQYQLNATVYPNDDSLLAD-E 65 Query: 65 NTFEELEKHLG 75 N L G Sbjct: 66 NVDAVLVTSWG 76 >3DC2-A nrPDB Length = 529 Score = 27.8 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 47/126 (37%), Gaps = 16/126 (12%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 K V G R IG+ VAQ +A G + + A+AA LG + L+ +A+ Sbjct: 143 KTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAA--QLGIELLSLDDLLARADF 199 Query: 63 VQNTFEELEKHLGRVN-----------FLVNAA--GINRDGLLVRTKTEDMVSQLHTNLL 109 + + + G ++ +VNAA G+ + L T V ++ Sbjct: 200 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVF 259 Query: 110 GSMLTC 115 + Sbjct: 260 ATEPCT 265 >1LEH-A nrPDB Length = 364 Score = 27.8 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 26/55 (47%), Gaps = 9/55 (16%) Query: 12 RGIG---RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLA------FSCDV 57 +G+G +A+ + + +G +L V N AA + G D +A +CD+ Sbjct: 179 QGLGNVAKALCKKLNTEGAKLVVTDVNKAAVSAAVAEEGADAVAPNAIYGVTCDI 233 >1QQV-A nrPDB Length = 67 Score = 27.8 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 18/56 (32%), Gaps = 11/56 (19%) Query: 77 VNFLVNAA------GINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126 ++ LVN A G++ ED + G + A + QQ Sbjct: 9 LDVLVNTAAEDLPRGVDPSRKENHLSDEDFKAVF-----GMTRSAFANLPLWKQQN 59 >6GBN-A nrPDB Length = 438 Score = 27.8 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G +G+ A + G R+ V ++ A + G + D K D Sbjct: 220 KVAVVAGYGD-VGKGSAASLRGAGARVIVTE--IDPICALQAAMDGYEVKKMADAVKRAD 276 Query: 63 V 63 + Sbjct: 277 I 277 >1IE3-A nrPDB Length = 312 Score = 27.4 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 48/134 (35%), Gaps = 20/134 (14%) Query: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 62 KV V G + GIG+A+A L+ + G++ + D+ + D++ Sbjct: 2 KVA-VLGAAGGIGQALALLLKTQ---------LPSGSELSLYDIAPVTPGVAVDLSHIPT 51 Query: 63 VQNT----FEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 118 E+ L + ++ +AG+ R + R+ + N + Sbjct: 52 AVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRS------DLFNVNAGIVKNLVQQV 105 Query: 119 MRTMIQQQGGSIVN 132 +T + G I N Sbjct: 106 AKTCPKACIGIITN 119 >5YZ0-C nrPDB Length = 791 Score = 27.4 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 15/43 (34%) Query: 26 GYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFE 68 G A +LE A A + DV+ +H V + Sbjct: 50 GAHGDFTADDLEELDTLASQALSQCPAAARDVSSDHKVHRLLD 92 >4D3S-A nrPDB Length = 293 Score = 27.4 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 16/31 (51%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAG 44 +G+A+A + GY L V R A+A A Sbjct: 19 MGQAMAGALLEAGYELTVWNRTKAKAEALAE 49 >3QWB-A nrPDB Length = 334 Score = 27.4 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 31/78 (39%), Gaps = 10/78 (12%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL--AFSCDV----- 57 +F + G+G + QL+ KG +A E K A + G ++L A D+ Sbjct: 152 VLLFAAAGGVGLILNQLLKMKGAHTIAVASTDEKLK-IAKEYGAEYLINASKEDILRQVL 210 Query: 58 --AKEHDVQNTFEELEKH 73 V +F+ + K Sbjct: 211 KFTNGKGVDASFDSVGKD 228 >6H5E-B nrPDB Length = 437 Score = 27.4 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 5/23 (21%), Positives = 9/23 (39%) Query: 63 VQNTFEELEKHLGRVNFLVNAAG 85 N F + G ++ +VN Sbjct: 128 FTNFFRDQMDRFGEIDIMVNNIA 150 >4Y4N-A nrPDB Length = 286 Score = 27.4 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE 37 V V GG G+ A+ +A++GY++ V+ R+L Sbjct: 55 VAIVGGGPSGL--TAARYIAKEGYKVVVLERHLA 86 >3CJR-A nrPDB Length = 254 Score = 27.0 bits (59), Expect = 6.5, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 25/81 (30%), Gaps = 14/81 (17%) Query: 16 RAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFE------- 68 +A+A+ + R G ++ + AA LGG L D + + Sbjct: 112 KALARHL-RPGDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRNGVRPR 170 Query: 69 ------ELEKHLGRVNFLVNA 83 E G + LV Sbjct: 171 FLEGSLEAALPFGPFDLLVAN 191 >5EVM-A nrPDB Length = 529 Score = 27.0 bits (59), Expect = 6.7, Method: Composition-based stats. Identities = 9/15 (60%), Positives = 11/15 (73%) Query: 216 LLESPYITGHVLVVD 230 LLES ITG ++ VD Sbjct: 256 LLESDSITGQIIYVD 270 >3K96-A nrPDB Length = 356 Score = 27.0 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 33/88 (37%), Gaps = 2/88 (2%) Query: 10 GSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEE 69 G+ G A+A ++ARKG ++ + + + + G ++ + ++ + Sbjct: 36 GAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAE-GVNNRYLP-NYPFPETLKAYCDL 93 Query: 70 LEKHLGRVNFLVNAAGINRDGLLVRTKT 97 G + L+ ++ R K Sbjct: 94 KASLEGVTDILIVVPSFAFHEVITRMKP 121 >3K4W-A nrPDB Length = 291 Score = 27.0 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 24/65 (36%), Gaps = 15/65 (23%) Query: 134 GSIVGLKGNSGQSVYSASKG---------GLVGFSRALAK----EVARKKIRVNVVAPGF 180 S++G N+ + + +K + +R A E+ IR+ + PG Sbjct: 71 SSVLGSVSNADVA--AVAKAYPDKFHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGV 128 Query: 181 VHTDM 185 T M Sbjct: 129 WATPM 133 >4MIT-A nrPDB Length = 186 Score = 27.0 bits (59), Expect = 6.9, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 18/57 (31%), Gaps = 5/57 (8%) Query: 17 AVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKH 73 A+ + + +G + A+ E C +++ F+E K Sbjct: 131 AIVKRLTEQGMTVINTAKGEELKNRIKA-----VKYIECSAKTSENLKTVFDEAVKT 182 >3JTJ-A nrPDB Length = 253 Score = 27.0 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 24/76 (31%), Gaps = 6/76 (7%) Query: 20 QLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRV-- 77 + +A G ++A + A GG+ D E+ +H G Sbjct: 39 RALAS-GADRVIVATDHPDVVKAVEAAGGEVCLTRAD---HQSGTERLAEVIEHYGFADD 94 Query: 78 NFLVNAAGINRDGLLV 93 + +VN G V Sbjct: 95 DIIVNVQGDEPLVPPV 110 >1HSZ-A nrPDB Length = 374 Score = 27.0 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 17/86 (19%) Query: 4 VCAVFGGS-------RGIGRAVAQLMARKGY-RLAVIARNLEGAKAAAGDLGGDHLAFSC 55 V V GS G+G + G R+ + N + A A +LG Sbjct: 186 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKF-AKAKELGATECI--- 241 Query: 56 DVAKEHDVQNTFEELEKHL--GRVNF 79 D + +E+ K + G V+F Sbjct: 242 ---NPQDYKKPIQEVLKEMTDGGVDF 264 >1ZK7-A nrPDB Length = 467 Score = 27.0 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 20/34 (58%), Gaps = 2/34 (5%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARN 35 +++ + GS + +AQ AR G ++ V+ARN Sbjct: 177 ERLAVI--GSSVVALELAQAFARLGSKVTVLARN 208 >5JH1-A nrPDB Length = 309 Score = 27.0 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 2/38 (5%) Query: 119 MRTMIQQQGGSI--VNVGSIVGLKGNSGQSVYSASKGG 154 R + G I V +GS G G +VY+A K G Sbjct: 1 ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAG 38 >4DLL-A nrPDB Length = 320 Score = 27.0 bits (59), Expect = 7.6, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 16/35 (45%) Query: 10 GSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAG 44 G+ +G +A+ + GY L V R A + A Sbjct: 38 GTGSMGLPMARRLCEAGYALQVWNRTPARAASLAA 72 >5HC7-A nrPDB Length = 261 Score = 27.0 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 25/80 (31%), Gaps = 6/80 (7%) Query: 19 AQLMARK----GYRLAVIARNLEGAKAAAGDLGG--DHLAFSCDVAKEHDVQNTFEELEK 72 A+ +++ + LAV E AA + +H D E + Sbjct: 124 AEGLSQANKGMHFILAVAYGGREDIVEAARKIAAKVEHGILRPDDIDEATFEQHLMTNIT 183 Query: 73 HLGRVNFLVNAAGINRDGLL 92 + L+ AAG R Sbjct: 184 KFPSPDLLIRAAGEQRLSNF 203 >3RHA-A nrPDB Length = 482 Score = 27.0 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 28/76 (36%), Gaps = 4/76 (5%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVI-ARNLEGAKAAAGDLGGDHLAFSCDVAK 59 +D+ + G G A+ + + G +AV+ AR+ G + + G L Sbjct: 6 LDRDVVIVGAGPS-GLTAARELKKAGLSVAVLEARDRVGGRTWTDTIDGAMLEIGGQWVS 64 Query: 60 EHDVQNTFEELEKHLG 75 Q EL LG Sbjct: 65 PD--QTVLMELLDELG 78 >5A3V-A nrPDB Length = 329 Score = 27.0 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 33/106 (31%), Gaps = 18/106 (16%) Query: 5 CAVFGGSRGIGRAVAQLMAR-KGYRLAVI--ARNLEGAKAAAGDLGGDHLAFSCDVAKEH 61 V S G+G A +A+ + ARN+E K+ D D Sbjct: 159 ILVTAASGGVG-HYAVQLAKLANAHVTATCGARNIEFVKSLGADE-------VLDYKTPE 210 Query: 62 DVQNTFEELEKHLG-RVNFLVNAAGINRDGLLVRTKTEDMVSQLHT 106 L+ G + + +V+ A + +E+ + Sbjct: 211 G-----AALKSPSGKKYDAVVHCANGIPFSVFEPNLSEN-GKVIDI 250 >5C1C-A nrPDB Length = 299 Score = 27.0 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 11/93 (11%), Positives = 28/93 (30%), Gaps = 3/93 (3%) Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGS--MLTCKA 117 E V F + G + + N AG + + + N+ + + + Sbjct: 157 EGAVDYIFGDASVWFGECDIVSNGAGAITASSRETSSDSGWYAIDNCNIKAASGVSLTEE 216 Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNS-GQSVYS 149 + ++ S++ N G + + Sbjct: 217 VYLGRPWRVLARVIYQNSVLSDIINPKGWTTMA 249 >3CGD-A nrPDB Length = 480 Score = 27.0 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 41/117 (35%), Gaps = 15/117 (12%) Query: 4 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGA----KAAAGDLGGDHLAFSCDVAK 59 V + GG+ IG +A+ G ++ +I RN A + + ++ Sbjct: 189 VTIIGGGA--IGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILT 246 Query: 60 EHDVQNT-----FEELEKHLG--RVNFLVNAAGINRDGLLVRTKT--EDMVSQLHTN 107 +V+ E +E G + + ++ + G+ + + + + N Sbjct: 247 NENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLEGTNIRTNHKGAIEVN 303 >2BC1-A nrPDB Length = 490 Score = 27.0 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%), Gaps = 2/33 (6%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIA 33 + +V V G+ IG +A+ RKG + +I Sbjct: 194 IKRVAVV--GAGYIGVELAEAFQRKGKEVVLID 224 >2A9F-A nrPDB Length = 398 Score = 26.6 bits (58), Expect = 8.6, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 40/106 (37%), Gaps = 12/106 (11%) Query: 1 MDKVCAVFGGSRGIGRAVAQLMARKGY-RLAVIARNLEGAKAAAGDLGGDHLAFSCDVAK 59 +D+V V G G ++ + + G ++ V+ + + A L HL V Sbjct: 186 LDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDKFGIINEQEAAQLAPHHLDI-AKVTN 244 Query: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLH 105 T E+ + + + G++ G+L + +S++ Sbjct: 245 REFKSGTLEDALE---GADIFI---GVSAPGVL----KAEWISKMA 280 >4TSK-A nrPDB Length = 350 Score = 26.6 bits (58), Expect = 8.7, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 20/52 (38%), Gaps = 2/52 (3%) Query: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF 53 DK AV G G A AQ + G+ + + R A D G +A Sbjct: 17 DKRIAVIGYGS-QGHAHAQNLRDSGFDVVIGLRPGSSWAKAEAD-GFRVMAV 66 >3G1U-A nrPDB Length = 437 Score = 26.6 bits (58), Expect = 8.7, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 19/49 (38%), Gaps = 2/49 (4%) Query: 15 GRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 63 G+ A + G R+ V ++ A + G +A DV + + Sbjct: 224 GKGCAAALRAFGARVVVTE--VDPINALQASMEGYQVALVEDVMADAHI 270 >5OCM-A nrPDB Length = 291 Score = 26.6 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 25/79 (31%), Gaps = 11/79 (13%) Query: 14 IGRAVAQLMARKGYRLAVIARNLEGAKAAAG----------DLGGDHLAFSCDVAKEHDV 63 +G+A+A + G+ V R+ A A D V+ V Sbjct: 14 MGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVVVCVSDHAAV 73 Query: 64 QNTFEELEKHLGRVNFLVN 82 + + L L LVN Sbjct: 74 RAVLDPLGDVLAG-RVLVN 91 >5YDP-A nrPDB Length = 235 Score = 26.6 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 118 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK---KIRVN 174 AM +++ + S V + + G S Q++YS + G G ++A A +++ K +IR + Sbjct: 54 AMHQLLESRDWSAVTMSDVAKAAGLSRQTLYS-TFGNRQGLAQAYALQLSEKFAGEIRDS 112 Query: 175 VV-APGFVHTDMTKDL 189 ++ PG + +++ + Sbjct: 113 IIRHPGQIELALSEGI 128 >2O0B-A nrPDB Length = 450 Score = 26.6 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 198 IPLGRFGETIEVAHAVVFLLESPYITGHVLVVDG 231 + R+ ++ +AV FL + ++G + + G Sbjct: 229 VAARRWDIEPDLTNAVAFL-SAAVVSGGTVRITG 261 >1HRD-A nrPDB Length = 449 Score = 26.6 bits (58), Expect = 9.3, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 43/133 (32%), Gaps = 28/133 (21%) Query: 13 GIG---RAVAQLMARKGYRLAVIA------RNLEGAKAAAG-----DLGGDHLAFSCDVA 58 G G A+ +A G + ++ + EG ++ D A Sbjct: 237 GFGNVAWGAAKKLAELGAKAVTLSGPDGYIYDPEGITTEEKINYMLEMRASGRNKVQDYA 296 Query: 59 KEHDVQNTFEELEKHLG-RVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM----- 112 + VQ F EK G +V+ ++ A E + N+ + Sbjct: 297 DKFGVQ--FFPGEKPWGQKVDIIMPCA------TQNDVDLEQAKKIVANNVKYYIEVANM 348 Query: 113 LTCKAAMRTMIQQ 125 T A+R ++QQ Sbjct: 349 PTTNEALRFLMQQ 361 >1VIM-A nrPDB Length = 200 Score = 26.6 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 15/36 (41%), Gaps = 2/36 (5%) Query: 3 KVCAVFGGSRG--IGRAVAQLMARKGYRLAVIARNL 36 + V G R I +A A + GY + V+ + Sbjct: 48 RSIFVIGAGRSGYIAKAFAMRLMHLGYTVYVVGETV 83 >4A5O-A nrPDB Length = 286 Score = 26.6 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 13/30 (43%) Query: 5 CAVFGGSRGIGRAVAQLMARKGYRLAVIAR 34 V G S +GR +A + G + V R Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHR 193 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.169 0.499 Lambda K H 0.267 0.0515 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,018,979 Number of Sequences: 36641 Number of extensions: 499157 Number of successful extensions: 3765 Number of sequences better than 10.0: 463 Number of HSP's better than 10.0 without gapping: 446 Number of HSP's successfully gapped in prelim test: 200 Number of HSP's that attempted gapping in prelim test: 2312 Number of HSP's gapped (non-prelim): 703 length of query: 237 length of database: 10,336,785 effective HSP length: 94 effective length of query: 143 effective length of database: 6,892,531 effective search space: 985631933 effective search space used: 985631933 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.6 bits)