BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8N335 (351 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2PLA-A nrPDB 717 0.0 1X0X-A nrPDB 536 e-153 4FGW-A nrPDB 320 5e-88 1YJ8-A nrPDB 292 1e-79 3K96-A nrPDB 134 5e-32 1Z82-A nrPDB 129 2e-30 1EVY-A nrPDB 104 6e-23 1TXG-A nrPDB 59 2e-09 1G5T-A nrPDB 30 1.8 2CYC-A nrPDB 29 2.9 2V7S-A nrPDB 28 4.5 >2PLA-A nrPDB Length = 349 Score = 717 bits (1850), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/349 (100%), Positives = 349/349 (100%) Query: 1 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH 60 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH Sbjct: 1 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH 60 Query: 61 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL Sbjct: 61 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 Query: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK Sbjct: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 Query: 181 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 240 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF Sbjct: 181 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 240 Query: 241 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ 300 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ Sbjct: 241 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ 300 Query: 301 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPE 349 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPE Sbjct: 301 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPE 349 >1X0X-A nrPDB Length = 354 Score = 536 bits (1380), Expect = e-153, Method: Compositional matrix adjust. Identities = 249/347 (71%), Positives = 297/347 (85%) Query: 4 APLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENV 63 A KVCIVGSGNWGSA+AKI+G N +L +F V MWVFEE + G+KLT+IIN HENV Sbjct: 7 ASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENV 66 Query: 64 KYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKG 123 KYLPGHKLP NVVA+ ++ +A +DAD+L+FV+PHQFI +ICD++ G + A GI+LIKG Sbjct: 67 KYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKG 126 Query: 124 IDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELL 183 +DEGP GLKLIS++I E++GI +SVLMGANIA+EVA EKFCETTIG K G L KEL+ Sbjct: 127 VDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKELM 186 Query: 184 QTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARI 243 QTPNFRITVV + DTVE+CGALKN+VAVGAGFCDGL GDNTKAAVIRLGLMEMIAFA++ Sbjct: 187 QTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKL 246 Query: 244 FCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQ 303 FC G VS+ATFLESCGVADLITTCYGGRNR+VAEAFARTGK+IE+LEKE+LNGQKLQGP+ Sbjct: 247 FCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPE 306 Query: 304 TSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEH 350 T+ E+Y IL+ KGL+DKFPLF AVY++CYE +PV E + CLQ+HPEH Sbjct: 307 TARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEH 353 >4FGW-A nrPDB Length = 391 Score = 320 bits (821), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 160/349 (45%), Positives = 224/349 (64%), Gaps = 10/349 (2%) Query: 2 AAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQK-FASTVKMWVFEETVNGRKLTDIINNDH 60 A P KV ++GSGNWG+ +AK++ N K + FA V+MWVFEE +NG KLT+IIN H Sbjct: 31 AEKPFKVTVIGSGNWGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRH 90 Query: 61 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 +NVKYLPG LP+N+VA +L ++V+D D++VF IPHQF+ RIC ++ G V I+ Sbjct: 91 QNVKYLPGITLPDNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISC 150 Query: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMEN----- 175 +KG + G +G++L+S I E++GI L GANIA EVA E + ETT+ + ++ Sbjct: 151 LKGFEVGAKGVQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEG 210 Query: 176 ----GLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIR 231 + K L P F ++V++D + +CGALKN+VA+G GF +GL G+N AA+ R Sbjct: 211 KDVDHKVLKALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQR 270 Query: 232 LGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEK 291 +GL E+I F ++F + ES GVADLITTC GGRN +VA A +GK E EK Sbjct: 271 VGLGEIIRFGQMFFPESREETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEK 330 Query: 292 EMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEM 340 E+LNGQ QG T EV+ L+ G ++ FPLF AVYQI Y + P++ + Sbjct: 331 ELLNGQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNL 379 >1YJ8-A nrPDB Length = 375 Score = 292 bits (748), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 146/349 (41%), Positives = 220/349 (63%), Gaps = 7/349 (2%) Query: 5 PLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVK 64 PLK+ I+GSGNW SA++K++G N K F + V+MW+ +E VNG ++ DIINN HEN K Sbjct: 21 PLKISILGSGNWASAISKVVGTNAKNNYLFENEVRMWIRDEFVNGERMVDIINNKHENTK 80 Query: 65 YLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEI----TGRVPKKALGITL 120 YL G LP N+VA S+L+ + DADLL+F++P Q++ + I + ++ A I+L Sbjct: 81 YLKGVPLPHNIVAHSDLASVINDADLLIFIVPCQYLESVLASIKESESIKIASHAKAISL 140 Query: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 KG +KL S+ I + + I S L GANIA +VA E F E TIG ++ ++++ Sbjct: 141 TKGFIVKKNQMKLCSNYISDFLNIPCSALSGANIAMDVAMENFSEATIGGNDKDSLVIWQ 200 Query: 181 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 240 + P F+I V++ VE+CGALKNI+ + GFCDGL N+K+A+IR G+ EMI F Sbjct: 201 RVFDLPYFKINCVNETIEVEICGALKNIITLACGFCDGLNLPTNSKSAIIRNGINEMILF 260 Query: 241 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFART--GKTIEELEKEMLNGQK 298 ++F + + + LESCG AD+IT+ GRN + + F ++ KT EELE E+L GQK Sbjct: 261 GKVFFQ-KFNENILLESCGFADIITSFLAGRNAKCSAEFIKSTPKKTWEELENEILKGQK 319 Query: 299 LQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSH 347 LQG T VY ++K+K + ++FPLFT +++I +E+ +L ++ Sbjct: 320 LQGTVTLKYVYHMIKEKNMTNEFPLFTVLHKISFENEDPSSLLKTFMNN 368 >3K96-A nrPDB Length = 356 Score = 134 bits (337), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 100/354 (28%), Positives = 178/354 (50%), Gaps = 29/354 (8%) Query: 2 AAAPLK--VCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINND 59 A P K + I+G+G+WG+A+A ++ +K QK V++W +E + +NN Sbjct: 24 AMEPFKHPIAILGAGSWGTALALVL---ARKGQK----VRLWSYESDHVDEMQAEGVNN- 75 Query: 60 HENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGIT 119 +YLP + PE + A +L +++ ++ V+P H + + + K Sbjct: 76 ----RYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAW 131 Query: 120 LIKGIDEGPEGLKLISDIIREKMG-IDISVLMGANIANEVAAEKFCETTIGSKVMENGLL 178 KG+ +G +L+ +++ ++G + ++V+ G ++A EVAA ++ S + Sbjct: 132 GTKGLAKGS---RLLHEVVATELGQVPMAVISGPSLATEVAANLPTAVSLASNNSQFSKD 188 Query: 179 FKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMI 238 E L FR+ DD VELCG++KNI+A+ G DGL+ G N +AA+I GL EM Sbjct: 189 LIERLHGQRFRVYKNDDMIGVELCGSVKNILAIATGISDGLKLGSNARAALITRGLTEMG 248 Query: 239 AFARIFCKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTGKTIEELEKEMLNG 296 +F G+ T T L G+ DL+ TC RNRR A G+ +++ E + G Sbjct: 249 RLVSVFG-GKQETLTGL--AGLGDLVLTCTDNQSRNRRFGLAL---GEGVDKKEAQQAIG 302 Query: 297 QKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYES-RPVQEMLSCLQSHPE 349 Q ++G + +V+ + ++ + + PL V++I +E P Q + L+ P+ Sbjct: 303 QAIEGLYNTDQVHALAQKHAI--EMPLTFQVHRILHEDLDPQQAVQELLERSPK 354 >1Z82-A nrPDB Length = 335 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 103/344 (29%), Positives = 170/344 (49%), Gaps = 37/344 (10%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 ++ ++G+G+WG+ A+++ N V +W +++ D+IN H + Y Sbjct: 15 MRFFVLGAGSWGTVFAQMLHEN-------GEEVILWA-----RRKEIVDLINVSHTS-PY 61 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVP-KKALGITLIKGI 124 + K+ V +N E ++ D+LV IP Q+I E R+P K ++ + L KGI Sbjct: 62 VEESKI---TVRATNDLEEIKKEDILVIAIPVQYIR----EHLLRLPVKPSMVLNLSKGI 114 Query: 125 DEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQ 184 + + K +S+I+ E +G +VL G + A EVA + T+ EN ++ + Sbjct: 115 E--IKTGKRVSEIVEEILGCPYAVLSGPSHAEEVAKKLPTAVTLAG---ENSKELQKRIS 169 Query: 185 TPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIF 244 T FR+ +D VE+ GALKN++A+ AG DG DN KAA+ G+ E+ F F Sbjct: 170 TEYFRVYTCEDVVGVEIAGALKNVIAIAAGILDGFGGWDNAKAALETRGIYEIARFGMFF 229 Query: 245 CKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTGKTIEELEKEMLNGQKLQGP 302 Q TF+ G+ DL+ TC RNRR E AR ++ LE + Q ++G Sbjct: 230 GADQ---KTFMGLAGIGDLMVTCNSRYSRNRRFGELIARGFNPLKLLES---SNQVVEGA 283 Query: 303 QTSAEVYRILKQKGLLDKFPLFTAVYQICYESR-PVQEMLSCLQ 345 T V +I K+ + P+ VY++ YE + P+Q M ++ Sbjct: 284 FTVKAVMKIAKENKI--DMPISEEVYRVVYEGKPPLQSMRDLMR 325 >1EVY-A nrPDB Length = 366 Score = 104 bits (259), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 101/352 (28%), Positives = 171/352 (48%), Gaps = 38/352 (10%) Query: 7 KVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMW-VFEETVNGRKLTDIINNDHENVKY 65 K + GSG +G+A+A ++ ++ V +W + EE V ++N ENV + Sbjct: 17 KAVVFGSGAFGTALAMVLSKKCRE-------VCVWHMNEEEVR------LVNEKRENVLF 63 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRV-----PKKALGITL 120 L G +L N+ S++ +A A++++FVIP QF+ ++ G + K+ + Sbjct: 64 LKGVQLASNITFTSDVEKAYNGAEIILFVIPTQFLRGFFEKSGGNLIAYAKEKQVPVLVC 123 Query: 121 IKGIDEGPEGLKLISDIIREKMGID-ISVLMGANIANEVAAEKFCETTIGSKVMENGLLF 179 KGI+ LK ++II E + +SVL G + A EVA F +I S + Sbjct: 124 TKGIERST--LKFPAEIIGEFLPSPLLSVLAGPSFAIEVATGVFTCVSIASADINVARRL 181 Query: 180 KELLQTPNFRITVVDDADTV--ELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEM 237 + ++ T + DTV E+ A+KN++A+G+G +GL G N +AA+I GL+E+ Sbjct: 182 QRIMSTGDRSFVCWATTDTVGCEVASAVKNVLAIGSGVANGLGMGLNARAALIMRGLLEI 241 Query: 238 IAFARIFCKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTGKTIEELEKEMLN 295 G +A F G+ DL TC RN V + + G IEE+++ + Sbjct: 242 RDLTAAL--GGDGSAVF-GLAGLGDLQLTCSSELSRNFTVGKKLGK-GLPIEEIQRT--S 295 Query: 296 GQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESR----PVQEMLSC 343 +G T+ + R+ KQ L K PL +Y+I Y+ + + ++LSC Sbjct: 296 KAVAEGVATADPLMRLAKQ--LKVKMPLCHQIYEIVYKKKNPRDALADLLSC 345 >1TXG-A nrPDB Length = 335 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 58/222 (26%), Positives = 93/222 (41%), Gaps = 19/222 (8%) Query: 128 PEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPN 187 PE + + +RE+ + G IA EVA S + KE+ +T Sbjct: 118 PEAVWRLKHDLRERT----VAITGPAIAREVAKRMPTTVVFSSPSESSANKMKEIFETEY 173 Query: 188 FRITVVDDADTVELCGALKNIVAVGAGFCDGLRCG-----DNTKAAVIRLGLMEMIAFAR 242 F + V D E+ ALKN+ ++ + G N K + + EM Sbjct: 174 FGVEVTTDIIGTEITSALKNVYSIAIAWIRGYESRKNVEMSNAKGVIATRAINEMAELIE 233 Query: 243 IFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFAR---TGKTIEELEKEMLNGQKL 299 I G TA L G DLI T GGRN + E + + +EELE+ + + Sbjct: 234 ILG-GDRETAFGL--SGFGDLIATFRGGRNGMLGELLGKGLSIDEAMEELERRGVG--VV 288 Query: 300 QGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEML 341 +G +T+ + YR+ + K L ++Y++ YE V+E+L Sbjct: 289 EGYKTAEKAYRLSSKINADTK--LLDSIYRVLYEGLKVEEVL 328 >1G5T-A nrPDB Length = 196 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 19/34 (55%) Query: 317 LLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEH 350 LLD L Y + Y+ P++E++S L + P H Sbjct: 120 LLDMVVLDELTYMVAYDYLPLEEVISALNARPGH 153 >2CYC-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 45/190 (23%), Positives = 77/190 (40%), Gaps = 38/190 (20%) Query: 101 HRICDEITGRVPKKALGITLIKGI---DEGPEGLK---LISDI---IREKMGIDISVLMG 151 H I EI+G + LG L+ G D G+K ++D I +K+G D+ V+ Sbjct: 36 HYIGFEISGYI---HLGTGLMAGAKIADFQKAGIKTRVFLADWHSWINDKLGGDLEVIQE 92 Query: 152 ANIAN-EVAAEKFCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVELCGALKNIVA 210 + +V EK E G +L E+L+ ++ TV+D + V L +++I Sbjct: 93 VALKYFKVGMEKSIEVMGGDPKKVEFVLASEILEKGDYWQTVIDISKNVTLSRVMRSITI 152 Query: 211 VGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGG 270 +G + + D K + M+ A IF +G +T + G Sbjct: 153 MGRQMGEAI---DFAKL------IYPMMQVADIFYQG----------------VTIAHAG 187 Query: 271 RNRRVAEAFA 280 ++R A A Sbjct: 188 MDQRKAHVIA 197 >2V7S-A nrPDB Length = 215 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 24/112 (21%), Positives = 50/112 (44%), Gaps = 15/112 (13%) Query: 103 ICDEITGRVPKKALGITLIKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEK 162 +CD++T + ++ + +++ G E K+ ++I+RE+ +++ NE A Sbjct: 103 LCDKLTADIARRPIANSVMFGATFSAEDFKIAANIVREEAA-KYGATTESSLFNESAKRD 161 Query: 163 FCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAG 214 + V NG F+ LLQ + + D C L+ ++ + AG Sbjct: 162 Y-------DVQGNGYEFR-LLQIKFATLNITGD------CFLLQKVLDLPAG 199 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2PLA-A nrPDB 495 e-141 1X0X-A nrPDB 493 e-140 4FGW-A nrPDB 461 e-130 1YJ8-A nrPDB 436 e-122 3K96-A nrPDB 351 2e-97 1Z82-A nrPDB 322 2e-88 1EVY-A nrPDB 311 3e-85 1TXG-A nrPDB 227 7e-60 Sequences not found previously or not previously below threshold: 3C7A-A nrPDB 40 0.001 3HWR-A nrPDB 39 0.003 5UAU-A nrPDB 35 0.042 2GRA-A nrPDB 35 0.043 1VJT-A nrPDB 34 0.091 2HQM-A nrPDB 33 0.16 1BG6-A nrPDB 32 0.29 5WNO-A nrPDB 32 0.34 1HSZ-A nrPDB 32 0.53 3WFI-A nrPDB 32 0.59 3U95-A nrPDB 31 0.94 1EE2-A nrPDB 30 1.1 1U3W-A nrPDB 30 1.5 1HSO-A nrPDB 30 1.7 3HFN-A nrPDB 30 1.8 6BII-A nrPDB 30 1.8 2EW2-A nrPDB 29 3.1 4A7P-A nrPDB 29 3.1 6ACQ-A nrPDB 29 4.6 5AYV-A nrPDB 28 5.0 4WJI-A nrPDB 28 7.8 3L5H-A nrPDB 27 9.1 6A0R-B nrPDB 27 9.4 >2PLA-A nrPDB Length = 349 Score = 495 bits (1275), Expect = e-141, Method: Composition-based stats. Identities = 349/349 (100%), Positives = 349/349 (100%) Query: 1 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH 60 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH Sbjct: 1 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH 60 Query: 61 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL Sbjct: 61 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 Query: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK Sbjct: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 Query: 181 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 240 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF Sbjct: 181 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 240 Query: 241 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ 300 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ Sbjct: 241 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ 300 Query: 301 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPE 349 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPE Sbjct: 301 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPE 349 >1X0X-A nrPDB Length = 354 Score = 493 bits (1268), Expect = e-140, Method: Composition-based stats. Identities = 249/349 (71%), Positives = 298/349 (85%) Query: 2 AAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHE 61 + A KVCIVGSGNWGSA+AKI+G N +L +F V MWVFEE + G+KLT+IIN HE Sbjct: 5 SMASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHE 64 Query: 62 NVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLI 121 NVKYLPGHKLP NVVA+ ++ +A +DAD+L+FV+PHQFI +ICD++ G + A GI+LI Sbjct: 65 NVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLI 124 Query: 122 KGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKE 181 KG+DEGP GLKLIS++I E++GI +SVLMGANIA+EVA EKFCETTIG K G L KE Sbjct: 125 KGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKE 184 Query: 182 LLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFA 241 L+QTPNFRITVV + DTVE+CGALKN+VAVGAGFCDGL GDNTKAAVIRLGLMEMIAFA Sbjct: 185 LMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFA 244 Query: 242 RIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQG 301 ++FC G VS+ATFLESCGVADLITTCYGGRNR+VAEAFARTGK+IE+LEKE+LNGQKLQG Sbjct: 245 KLFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQG 304 Query: 302 PQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEH 350 P+T+ E+Y IL+ KGL+DKFPLF AVY++CYE +PV E + CLQ+HPEH Sbjct: 305 PETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEH 353 >4FGW-A nrPDB Length = 391 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 161/359 (44%), Positives = 227/359 (63%), Gaps = 10/359 (2%) Query: 2 AAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQK-FASTVKMWVFEETVNGRKLTDIINNDH 60 A P KV ++GSGNWG+ +AK++ N K + FA V+MWVFEE +NG KLT+IIN H Sbjct: 31 AEKPFKVTVIGSGNWGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRH 90 Query: 61 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 +NVKYLPG LP+N+VA +L ++V+D D++VF IPHQF+ RIC ++ G V I+ Sbjct: 91 QNVKYLPGITLPDNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISC 150 Query: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMEN----- 175 +KG + G +G++L+S I E++GI L GANIA EVA E + ETT+ + ++ Sbjct: 151 LKGFEVGAKGVQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEG 210 Query: 176 ----GLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIR 231 + K L P F ++V++D + +CGALKN+VA+G GF +GL G+N AA+ R Sbjct: 211 KDVDHKVLKALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQR 270 Query: 232 LGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEK 291 +GL E+I F ++F + ES GVADLITTC GGRN +VA A +GK E EK Sbjct: 271 VGLGEIIRFGQMFFPESREETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEK 330 Query: 292 EMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEH 350 E+LNGQ QG T EV+ L+ G ++ FPLF AVYQI Y + P++ + ++ H Sbjct: 331 ELLNGQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLH 389 >1YJ8-A nrPDB Length = 375 Score = 436 bits (1120), Expect = e-122, Method: Composition-based stats. Identities = 146/349 (41%), Positives = 219/349 (62%), Gaps = 7/349 (2%) Query: 5 PLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVK 64 PLK+ I+GSGNW SA++K++G N K F + V+MW+ +E VNG ++ DIINN HEN K Sbjct: 21 PLKISILGSGNWASAISKVVGTNAKNNYLFENEVRMWIRDEFVNGERMVDIINNKHENTK 80 Query: 65 YLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEIT----GRVPKKALGITL 120 YL G LP N+VA S+L+ + DADLL+F++P Q++ + I ++ A I+L Sbjct: 81 YLKGVPLPHNIVAHSDLASVINDADLLIFIVPCQYLESVLASIKESESIKIASHAKAISL 140 Query: 121 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 KG +KL S+ I + + I S L GANIA +VA E F E TIG ++ ++++ Sbjct: 141 TKGFIVKKNQMKLCSNYISDFLNIPCSALSGANIAMDVAMENFSEATIGGNDKDSLVIWQ 200 Query: 181 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 240 + P F+I V++ VE+CGALKNI+ + GFCDGL N+K+A+IR G+ EMI F Sbjct: 201 RVFDLPYFKINCVNETIEVEICGALKNIITLACGFCDGLNLPTNSKSAIIRNGINEMILF 260 Query: 241 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFART--GKTIEELEKEMLNGQK 298 ++F + + + LESCG AD+IT+ GRN + + F ++ KT EELE E+L GQK Sbjct: 261 GKVFFQ-KFNENILLESCGFADIITSFLAGRNAKCSAEFIKSTPKKTWEELENEILKGQK 319 Query: 299 LQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSH 347 LQG T VY ++K+K + ++FPLFT +++I +E+ +L ++ Sbjct: 320 LQGTVTLKYVYHMIKEKNMTNEFPLFTVLHKISFENEDPSSLLKTFMNN 368 >3K96-A nrPDB Length = 356 Score = 351 bits (901), Expect = 2e-97, Method: Composition-based stats. Identities = 97/354 (27%), Positives = 174/354 (49%), Gaps = 29/354 (8%) Query: 2 AAAPLK--VCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINND 59 A P K + I+G+G+WG+A+A ++ V++W +E + +NN Sbjct: 24 AMEPFKHPIAILGAGSWGTALALVLARK-------GQKVRLWSYESDHVDEMQAEGVNN- 75 Query: 60 HENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGIT 119 +YLP + PE + A +L +++ ++ V+P H + + + K Sbjct: 76 ----RYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAW 131 Query: 120 LIKGIDEGPEGLKLISDIIREKMG-IDISVLMGANIANEVAAEKFCETTIGSKVMENGLL 178 KG+ +G +L+ +++ ++G + ++V+ G ++A EVAA ++ S + Sbjct: 132 GTKGLAKGS---RLLHEVVATELGQVPMAVISGPSLATEVAANLPTAVSLASNNSQFSKD 188 Query: 179 FKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMI 238 E L FR+ DD VELCG++KNI+A+ G DGL+ G N +AA+I GL EM Sbjct: 189 LIERLHGQRFRVYKNDDMIGVELCGSVKNILAIATGISDGLKLGSNARAALITRGLTEMG 248 Query: 239 AFARIFCKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTGKTIEELEKEMLNG 296 +F G+ T T L G+ DL+ TC RNRR A G+ +++ E + G Sbjct: 249 RLVSVFG-GKQETLTGL--AGLGDLVLTCTDNQSRNRRFGLAL---GEGVDKKEAQQAIG 302 Query: 297 QKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYES-RPVQEMLSCLQSHPE 349 Q ++G + +V+ + ++ + + PL V++I +E P Q + L+ P+ Sbjct: 303 QAIEGLYNTDQVHALAQKHAI--EMPLTFQVHRILHEDLDPQQAVQELLERSPK 354 >1Z82-A nrPDB Length = 335 Score = 322 bits (825), Expect = 2e-88, Method: Composition-based stats. Identities = 103/346 (29%), Positives = 169/346 (48%), Gaps = 37/346 (10%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 ++ ++G+G+WG+ A+++ N V +W +++ D+IN H + Y Sbjct: 15 MRFFVLGAGSWGTVFAQMLHEN-------GEEVILWA-----RRKEIVDLINVSHTS-PY 61 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVP-KKALGITLIKGI 124 + K+ V +N E ++ D+LV IP Q+I E R+P K ++ + L KGI Sbjct: 62 VEESKI---TVRATNDLEEIKKEDILVIAIPVQYIR----EHLLRLPVKPSMVLNLSKGI 114 Query: 125 DEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQ 184 + + K +S+I+ E +G +VL G + A EVA + T+ EN ++ + Sbjct: 115 EI--KTGKRVSEIVEEILGCPYAVLSGPSHAEEVAKKLPTAVTLAG---ENSKELQKRIS 169 Query: 185 TPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIF 244 T FR+ +D VE+ GALKN++A+ AG DG DN KAA+ G+ E+ F F Sbjct: 170 TEYFRVYTCEDVVGVEIAGALKNVIAIAAGILDGFGGWDNAKAALETRGIYEIARFGMFF 229 Query: 245 CKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTGKTIEELEKEMLNGQKLQGP 302 Q TF+ G+ DL+ TC RNRR E AR ++ LE + Q ++G Sbjct: 230 GADQ---KTFMGLAGIGDLMVTCNSRYSRNRRFGELIARGFNPLKLLES---SNQVVEGA 283 Query: 303 QTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPV-QEMLSCLQSH 347 T V +I K+ + P+ VY++ YE +P Q M ++ Sbjct: 284 FTVKAVMKIAKENKI--DMPISEEVYRVVYEGKPPLQSMRDLMRRS 327 >1EVY-A nrPDB Length = 366 Score = 311 bits (797), Expect = 3e-85, Method: Composition-based stats. Identities = 99/352 (28%), Positives = 168/352 (47%), Gaps = 38/352 (10%) Query: 7 KVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMW-VFEETVNGRKLTDIINNDHENVKY 65 K + GSG +G+A+A ++ + V +W + EE V ++N ENV + Sbjct: 17 KAVVFGSGAFGTALAMVLSKKCR-------EVCVWHMNEEEVR------LVNEKRENVLF 63 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRV-----PKKALGITL 120 L G +L N+ S++ +A A++++FVIP QF+ ++ G + K+ + Sbjct: 64 LKGVQLASNITFTSDVEKAYNGAEIILFVIPTQFLRGFFEKSGGNLIAYAKEKQVPVLVC 123 Query: 121 IKGIDEGPEGLKLISDIIREKMGID-ISVLMGANIANEVAAEKFCETTIGSKVMENGLLF 179 KGI+ LK ++II E + +SVL G + A EVA F +I S + Sbjct: 124 TKGIERST--LKFPAEIIGEFLPSPLLSVLAGPSFAIEVATGVFTCVSIASADINVARRL 181 Query: 180 KELLQTPNFRITVV--DDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEM 237 + ++ T + D E+ A+KN++A+G+G +GL G N +AA+I GL+E+ Sbjct: 182 QRIMSTGDRSFVCWATTDTVGCEVASAVKNVLAIGSGVANGLGMGLNARAALIMRGLLEI 241 Query: 238 IAFARIFCKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTGKTIEELEKEMLN 295 G +A F G+ DL TC RN V + + G IEE+++ + Sbjct: 242 RDLTAAL--GGDGSAVF-GLAGLGDLQLTCSSELSRNFTVGKKLGK-GLPIEEIQRT--S 295 Query: 296 GQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESR----PVQEMLSC 343 +G T+ + R+ KQ L K PL +Y+I Y+ + + ++LSC Sbjct: 296 KAVAEGVATADPLMRLAKQ--LKVKMPLCHQIYEIVYKKKNPRDALADLLSC 345 >1TXG-A nrPDB Length = 335 Score = 227 bits (578), Expect = 7e-60, Method: Composition-based stats. Identities = 79/350 (22%), Positives = 147/350 (42%), Gaps = 40/350 (11%) Query: 8 VCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLP 67 V I+G+G GSA++ + +N + V++W E ++ I+ E+ + Sbjct: 3 VSILGAGAMGSALSVPLVDN-------GNEVRIWGTEFDT---EILKSISAGREHPRL-- 50 Query: 68 GHKLPENVVAMSN-LSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDE 126 G KL + L + +++A++++ + + + I + + + + + KG+ + Sbjct: 51 GVKLNGVEIFWPEQLEKCLENAEVVLLGVSTDGVLPVMSRILPYLKDQYIVL-ISKGLID 109 Query: 127 -------GPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLF 179 PE + + +RE+ + G IA EVA S + Sbjct: 110 FDNSVLTVPEAVWRLKHDLRERT----VAITGPAIAREVAKRMPTTVVFSSPSESSANKM 165 Query: 180 KELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCG-----DNTKAAVIRLGL 234 KE+ +T F + V D E+ ALKN+ ++ + G N K + + Sbjct: 166 KEIFETEYFGVEVTTDIIGTEITSALKNVYSIAIAWIRGYESRKNVEMSNAKGVIATRAI 225 Query: 235 MEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFART---GKTIEELEK 291 EM I G TA L G DLI T GGRN + E + + +EELE+ Sbjct: 226 NEMAELIEILG-GDRETAFGL--SGFGDLIATFRGGRNGMLGELLGKGLSIDEAMEELER 282 Query: 292 EMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEML 341 + ++G +T+ + YR+ + K L ++Y++ YE V+E+L Sbjct: 283 RGVG--VVEGYKTAEKAYRLSSKINADTK--LLDSIYRVLYEGLKVEEVL 328 >3C7A-A nrPDB Length = 404 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 33/178 (18%), Positives = 59/178 (33%), Gaps = 27/178 (15%) Query: 7 KVCIVGSGNWGSAVAKII----GNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHEN 62 KVC+ G GN ++ + G V+ L FA + W + + +LT I+N Sbjct: 4 KVCVCGGGNGAHTLSGLAASRDGVEVRVLTLFADEAERWT--KALGADELTVIVNEKDGT 61 Query: 63 VKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIK 122 + V + A+ AD+++ +P + V AL + Sbjct: 62 QTEVKSRP----KVITKDPEIAISGADVVILTVPAFAHEGYFQAMAPYVQDSALIV---- 113 Query: 123 GIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 180 G+ DI+ +K A V+ F ++ E G + Sbjct: 114 GLPSQAGFEFQCRDILGDK-------------AAAVSMMSFETLPWACRIKEFGRKVE 158 >3HWR-A nrPDB Length = 318 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 54/151 (35%), Gaps = 15/151 (9%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 +KV I+G+G G ++ + V + + V + T + E + Sbjct: 20 MKVAIMGAGAVGCYYGGMLA-------RAGHEVILIARPQHVQAIEATGL---RLETQSF 69 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGID 125 K V+ S+ AVQ ADL++F + + + K AL ++L G++ Sbjct: 70 DEQVK-----VSASSDPSAVQGADLVLFCVKSTDTQSAALAMKPALAKSALVLSLQNGVE 124 Query: 126 EGPEGLKLISDIIREKMGIDISVLMGANIAN 156 L+ + + + + G Sbjct: 125 NADTLRSLLEQEVAAAVVYVATEMAGPGHVR 155 >5UAU-A nrPDB Length = 322 Score = 35.1 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 48/128 (37%), Gaps = 15/128 (11%) Query: 75 VVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKG-----IDEGPE 129 V + E VQ +D+L + I I DEI + + + ++ G I++ Sbjct: 72 VKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLS 131 Query: 130 GLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPNFR 189 + +IR + V GA + T +E+G L ++LL + F Sbjct: 132 AFRPAPRVIRCMTNTPVVVREGATVY----------ATGTHAQVEDGRLMEQLLSSVGFC 181 Query: 190 ITVVDDAD 197 V +D Sbjct: 182 TEVEEDLI 189 >2GRA-A nrPDB Length = 277 Score = 35.1 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 48/128 (37%), Gaps = 15/128 (11%) Query: 75 VVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKG-----IDEGPE 129 V + E VQ +D+L + I I DEI + + + ++ G I++ Sbjct: 52 VKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLS 111 Query: 130 GLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPNFR 189 + +IR + V GA + T +E+G L ++LL + F Sbjct: 112 AFRPAPRVIRCMTNTPVVVREGATVY----------ATGTHAQVEDGRLMEQLLSSVGFC 161 Query: 190 ITVVDDAD 197 V +D Sbjct: 162 TEVEEDLI 169 >1VJT-A nrPDB Length = 483 Score = 33.9 bits (76), Expect = 0.091, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 +K+ I+G+G+ A+ +++G+ + + +++ + + I+ KY Sbjct: 13 MKISIIGAGSVRFAL-QLVGDIAQTEELSREDTHIYMMDVHERRLNASYIL-----ARKY 66 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLV 92 + P +V S+L EA+ AD ++ Sbjct: 67 VEELNSPVKIVKTSSLDEAIDGADFII 93 >2HQM-A nrPDB Length = 479 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 48/126 (38%), Gaps = 9/126 (7%) Query: 1 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQK-FASTVKMWVFEE----TVNGRKLTDI 55 + P KV +VG+G G +A + + + F+E T+ + + Sbjct: 181 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 240 Query: 56 INNDHEN--VKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQ-FIHRICDEITGRVP 112 IN + VK + + + N S+++ D D L++ I + + + + ++ Sbjct: 241 INVHKLSKIVKVEKNVE-TDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLN 299 Query: 113 KKALGI 118 I Sbjct: 300 SHDQII 305 >1BG6-A nrPDB Length = 359 Score = 32.4 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 44/115 (38%), Gaps = 11/115 (9%) Query: 4 APLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENV 63 ++G GN G A A + + + + + + E G + + Sbjct: 3 ESKTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQR-IKEIQDRGAIIAEG-------- 53 Query: 64 KYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGI 118 L G P+ + S++ AV+DAD+++ V+P I I + + L I Sbjct: 54 PGLAGTAHPDLLT--SDIGLAVKDADVILIVVPAIHHASIAANIASYISEGQLII 106 >5WNO-A nrPDB Length = 330 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 14/113 (12%), Positives = 37/113 (32%), Gaps = 15/113 (13%) Query: 11 VGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINN---DHENVKYLP 67 +G+G +G+ A I K K +K++ +++ L + N H+N+ + Sbjct: 30 LGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQSQTDEMLEEATNMFRLRHDNLLKII 89 Query: 68 GHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 120 G + ++ ++ P + + + + Sbjct: 90 GFCMHDD------------GLKIVTIYRPLGNLQNFLKLHKENLGAREQVLYC 130 >1HSZ-A nrPDB Length = 374 Score = 31.6 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 44/136 (32%), Gaps = 20/136 (14%) Query: 176 GLLFKELLQTPNFRITVVDD---ADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRL 232 G L T F V D ++ L+ + +G GF G N A + Sbjct: 134 GKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV--AKVTP 191 Query: 233 GLMEMIAFARIFCKGQVSTATFLE--SCGVADLITTCYGGRNRRVAEAFART-------- 282 G +F G V + + + G A +I A+ T Sbjct: 192 GST-----CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 246 Query: 283 GKTIEELEKEMLNGQK 298 K I+E+ KEM +G Sbjct: 247 KKPIQEVLKEMTDGGV 262 >3WFI-A nrPDB Length = 312 Score = 31.6 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 40/119 (33%), Gaps = 12/119 (10%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 +K+ I G+G GS ++ + ++ W N E Sbjct: 1 MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDG----WAEHVQQIKEHGLQANFNGKEVEAK 56 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGI 124 LP +V S + + DL++ + ++ +I + K + L+ GI Sbjct: 57 LP-------IVLQSEVEKE-DQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLCLLNGI 107 >3U95-A nrPDB Length = 477 Score = 30.9 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 +K+ IVG+G+ A+ +++ + + + +++ + + I+ KY Sbjct: 1 MKISIVGAGSVRFAL-QLVEDIAQTDELSREDTHIYLMDVHERRLNASYIL-----ARKY 54 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLV 92 + P VV +L EA++ AD ++ Sbjct: 55 VEELNSPVKVVKTESLDEAIEGADFII 81 >1EE2-A nrPDB Length = 373 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 32/136 (23%), Positives = 45/136 (33%), Gaps = 20/136 (14%) Query: 176 GLLFKELLQTPNFRITVVDDADTV---ELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRL 232 G L T F V D +V + L+ + VG GF G G K A + Sbjct: 133 GKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY--GSAVKVAKVTQ 190 Query: 233 GLMEMIAFARIFCKGQVSTATFLE--SCGVADLITTCYGGRNRRVAEAFART-------- 282 G +F G V + + + G A +I A+ T Sbjct: 191 GST-----CAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDY 245 Query: 283 GKTIEELEKEMLNGQK 298 K I+E+ EM NG Sbjct: 246 KKPIQEVLTEMSNGGV 261 >1U3W-A nrPDB Length = 374 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 42/124 (33%), Gaps = 20/124 (16%) Query: 188 FRITVVDD---ADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIF 244 F V D ++ L+ + +G GF G G K A + G +F Sbjct: 146 FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY--GSAVKVAKVTPGST-----CAVF 198 Query: 245 CKGQVSTATFLE--SCGVADLITTCYGGRNRRVAEAFART--------GKTIEELEKEML 294 G V + + + G A +I A+ T K I+E+ KEM Sbjct: 199 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 258 Query: 295 NGQK 298 +G Sbjct: 259 DGGV 262 >1HSO-A nrPDB Length = 374 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 41/124 (33%), Gaps = 20/124 (16%) Query: 188 FRITVVDD---ADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIF 244 F V D ++ L+ + +G GF G N A + G +F Sbjct: 146 FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV--AKVTPGST-----CAVF 198 Query: 245 CKGQVSTATFLE--SCGVADLITTCYGGRNRRVAEAFART--------GKTIEELEKEML 294 G V + + + G A +I A+ T K I+E+ KEM Sbjct: 199 GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 258 Query: 295 NGQK 298 +G Sbjct: 259 DGGV 262 >3HFN-A nrPDB Length = 72 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 8/60 (13%), Positives = 25/60 (41%) Query: 124 IDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELL 183 D ++ + ++I++ ++I ++ G I V + I + ++K+ + Sbjct: 6 FDTSLPSIRQLQNLIKQAAPVEIKLVTGDAITGRVLWQDPTCVCIADENSRQTTIWKQAI 65 >6BII-A nrPDB Length = 333 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 28/80 (35%), Gaps = 2/80 (2%) Query: 243 IFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGP 302 I G++ A + G I R + K +EEL +E + + Sbjct: 155 IVGFGRIGQAIAKRAKGFGMRILYTARSRKPEAEKELGAEFKPLEELLRE--SDFVVLAV 212 Query: 303 QTSAEVYRILKQKGLLDKFP 322 + E Y ++ ++ L P Sbjct: 213 PLTKETYHMINEERLRLMKP 232 >2EW2-A nrPDB Length = 316 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 41/119 (34%), Gaps = 11/119 (9%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 +K+ I G+G GS + ++ + W + N E V Sbjct: 4 MKIAIAGAGAMGSRLGIMLHQGGNDVTLIDQ----WPAHIEAIRKNGLIADFNGEEVVAN 59 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGI 124 LP + + + + DL++ + Q + + I + +K + L+ G+ Sbjct: 60 LP-------IFSPEEIDHQNEQVDLIIALTKAQQLDAMFKAIQPMITEKTYVLCLLNGL 111 >4A7P-A nrPDB Length = 446 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 35/223 (15%), Positives = 77/223 (34%), Gaps = 42/223 (18%) Query: 60 HENVK--YLPGHK--LPENVVA-----MSNLSEAVQDADLLVFVI--PHQ---------F 99 H+NV Y PG + NV A ++L+E V+DAD + + P + + Sbjct: 48 HQNVMPIYEPGLDALVASNVKAGRLSFTTDLAEGVKDADAVFIAVGTPSRRGDGHADLSY 107 Query: 100 IHRICDEITGRVPKKALGIT-LIKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEV 158 + EI + K ++ +T + G E ++I+++ V+ E Sbjct: 108 VFAAAREIAENLTKPSVIVTKSTVPVGTGDEVERIIAEVAP---NSGAKVVSNPEFLREG 164 Query: 159 AA----EKFCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAG 214 AA ++ +G++ + +E+ +++ A ++ G Sbjct: 165 AAIEDFKRPDRVVVGTEDEFARQVMREI----YRPLSLNQSAP----------VLFTGRR 210 Query: 215 FCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQVSTATFLES 257 + ++ N AV + E+ + + Sbjct: 211 TSELIKYAANAFLAVKITFINEIADLCEQVGADVQEVSRGIGM 253 >6ACQ-A nrPDB Length = 302 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 30/222 (13%), Positives = 69/222 (31%), Gaps = 5/222 (2%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 KVC++G+G GS +A+ ++ + + L+ ++ ++ Sbjct: 22 KKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLV--KKGKIEE 79 Query: 66 LPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGI---TLIK 122 ++ + +L+ A ++ + I + + K + T Sbjct: 80 ATKVEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETILASNTSSL 139 Query: 123 GIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKEL 182 I E K +I V+ + +A + + + G E+ Sbjct: 140 SITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIGKDPVEV 199 Query: 183 LQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDN 224 + P F + + E G L +A ++ G N Sbjct: 200 AEAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGAN 241 >5AYV-A nrPDB Length = 309 Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 17/135 (12%), Positives = 49/135 (36%), Gaps = 19/135 (14%) Query: 6 LKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKY 65 +++ ++G+G+ GS ++ + + V + + R+ D IN + +V Sbjct: 1 MRIYVLGAGSIGSLFGALLA-------RAGNDVTL------IGRREQVDAINKNGLHVFG 47 Query: 66 LPGHKL-PENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGI 124 + P+ + + DLL+ + + + + +++ G+ Sbjct: 48 AEEFTVKPKATIYAPE-----EPPDLLILAVKSYSTKTALECARQCIGRNTWVLSIQNGL 102 Query: 125 DEGPEGLKLISDIIR 139 LK +++ Sbjct: 103 GNEELALKYTPNVMG 117 >4WJI-A nrPDB Length = 293 Score = 27.8 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 24/58 (41%), Gaps = 2/58 (3%) Query: 82 SEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALG--ITLIKGIDEGPEGLKLISDI 137 +EAV+ ADL+V +P + EI + A+ + KG L D+ Sbjct: 59 AEAVEGADLVVVSVPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPKDV 116 >3L5H-A nrPDB Length = 589 Score = 27.4 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 9/73 (12%), Positives = 23/73 (31%), Gaps = 4/73 (5%) Query: 23 IIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLP----GHKLPENVVAM 78 ++ + +W ++ IIN +V + +L N++ Sbjct: 26 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTF 85 Query: 79 SNLSEAVQDADLL 91 L + V ++ Sbjct: 86 GQLEQNVYGITII 98 >6A0R-B nrPDB Length = 332 Score = 27.4 bits (59), Expect = 9.4, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 3 AAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFA 35 LK+ ++G G GSA ++ ++L F Sbjct: 1 MEALKIALLGGGTVGSAFYNLVLERAEELSAFG 33 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.128 0.314 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,151,070 Number of Sequences: 36641 Number of extensions: 388311 Number of successful extensions: 1452 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1378 Number of HSP's gapped (non-prelim): 52 length of query: 351 length of database: 10,336,785 effective HSP length: 98 effective length of query: 253 effective length of database: 6,745,967 effective search space: 1706729651 effective search space used: 1706729651 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.4 bits)