BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q8LQ68
(506 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
5ZQT-A nrPDB 947 0.0
4QS9-A nrPDB 647 0.0
1BDG-A nrPDB 274 6e-74
5HFU-A nrPDB 273 2e-73
4FOI-A nrPDB 271 4e-73
1BG3-A nrPDB 271 5e-73
3O1W-A nrPDB 265 4e-71
3HM8-A nrPDB 258 3e-69
3W0L-A nrPDB 251 5e-67
1IG8-A nrPDB 247 9e-66
4DCH-A nrPDB 238 5e-63
3B8A-X nrPDB 234 8e-62
2YHX-A nrPDB 39 0.004
1HKG-A nrPDB 36 0.031
4OVD-A nrPDB 33 0.20
5ZEP-H nrPDB 30 2.0
2IZO-A nrPDB 29 4.0
4B2T-A nrPDB 29 5.0
6FPX-A nrPDB 29 5.4
6D7W-A nrPDB 29 6.2
5HFZ-A nrPDB 29 6.2
>5ZQT-A nrPDB
Length = 473
Score = 947 bits (2449), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 45 AAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGL 104
AAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGL
Sbjct: 12 AAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGL 71
Query: 105 FYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVK 164
FYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVK
Sbjct: 72 FYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVK 131
Query: 165 TEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME 224
TEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME
Sbjct: 132 TEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME 191
Query: 225 RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS 284
RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS
Sbjct: 192 RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS 251
Query: 285 GNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAH 344
GNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAH
Sbjct: 252 GNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAH 311
Query: 345 DASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYITL 404
DASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYITL
Sbjct: 312 DASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYITL 371
Query: 405 HVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCLE 464
HVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCLE
Sbjct: 372 HVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCLE 431
Query: 465 ATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASVE 506
ATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASVE
Sbjct: 432 ATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASVE 473
>4QS9-A nrPDB
Length = 474
Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 310/459 (67%), Positives = 377/459 (82%), Gaps = 2/459 (0%)
Query: 44 RAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHG 103
R A+++ E+ +TP + LR +ADAM EM GL +D + LKMLISYVDNLP+GDE G
Sbjct: 14 RVLAILKAFEEDCATPISKLRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKG 73
Query: 104 LFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFV 163
LFYALDLGGTNFRV+RV LGG+++RVV Q++EEV+IPPHLM G S ELF+FIA L FV
Sbjct: 74 LFYALDLGGTNFRVMRVLLGGKQERVVKQEFEEVSIPPHLMTGGSDELFNFIAEALAKFV 133
Query: 164 KTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAM 223
TE EDFHLPEGRQRELGFTF+FPV QTS+SSG+LIKWTKGFSI VG+DVV L++A+
Sbjct: 134 ATECEDFHLPEGRQRELGFTFAFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGALNKAL 193
Query: 224 ERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPR 283
ER GLDM++ ALVNDTVGTLAGGRY + DV AAVILGTGTNAAYVE A AIPKW GLLP+
Sbjct: 194 ERVGLDMRIAALVNDTVGTLAGGRYYNPDVVAAVILGTGTNAAYVERATAIPKWHGLLPK 253
Query: 284 SGNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLA 343
SG MVINMEWGNF+S LP +++D+ LDFESLNPGEQI EK+ISGMYLGEI+RR+LLK+A
Sbjct: 254 SGEMVINMEWGNFRSSHLPLTEFDHTLDFESLNPGEQILEKIISGMYLGEILRRVLLKMA 313
Query: 344 HDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYIT 403
DA+ FGD VP+KL FI+RTP MSAMH+DTS DLK +G+K+KDIL V TSL+ R +
Sbjct: 314 EDAAFFGDTVPSKLRIPFIIRTPHMSAMHNDTSPDLKIVGSKIKDILEVPTTSLKMRKVV 373
Query: 404 LHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCL 463
+ +C+++A RGARL+AAGIYGILKKLGRD + + Q++VIA+DGGL+EHY +F C+
Sbjct: 374 ISLCNIIATRGARLSAAGIYGILKKLGRDTTKDE--EVQKSVIAMDGGLFEHYTQFSECM 431
Query: 464 EATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQY 502
E++L +LLG+EA+ SV V +NDGSGIGAALLAASHS Y
Sbjct: 432 ESSLKELLGDEASGSVEVTHSNDGSGIGAALLAASHSLY 470
>1BDG-A nrPDB
Length = 451
Score = 274 bits (701), Expect = 6e-74, Method: Compositional matrix adjust.
Identities = 171/459 (37%), Positives = 253/459 (55%), Gaps = 31/459 (6%)
Query: 51 EVEQRFSTPTALLRGIADAMVEEMERGLR--ADPHAPLKMLISYVDNLPTGDEHGLFYAL 108
E+ + F I D M E M GL+ + + +KM SYV P G E G F AL
Sbjct: 14 EILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTPNGTETGNFLAL 73
Query: 109 DLGGTNFRVIRVQLGGREK--RVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTE 166
DLGGTN+RV+ V L G+ K R+ + Y IP M G+ ELF +IA L F++
Sbjct: 74 DLGGTNYRVLSVTLEGKGKSPRIQERTY---CIPAEKMSGSGTELFKYIAETLADFLENN 130
Query: 167 GEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ 226
G + ++ +LGFTFSFP Q ++ TL++WTKGFS +G G +V L ++++
Sbjct: 131 GM-----KDKKFDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQTELDKR 185
Query: 227 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSGN 286
L++K A+VNDTVGTLA D A +I+GTGTN AY+E ++ + G+ +
Sbjct: 186 ELNVKCVAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGV--KEPE 243
Query: 287 MVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLA 343
+VIN EWG F + R+ +D ++D +SL+PG+Q+YEKM+SGMYLGE+VR I++ L
Sbjct: 244 VVINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRHIIVYLV 303
Query: 344 HDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYIT 403
LF +P +L+ R L T ++ + D +H L + L D L V I
Sbjct: 304 EQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHLLYNTHYMLTDDLHVPVVEPIDNRIV 363
Query: 404 LHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCL 463
+ C++V +R A LA AGI IL+++ R V + +DG LY+ + KF C
Sbjct: 364 RYACEMVVKRAAYLAGAGIACILRRINRSEV----------TVGVDGSLYKFHPKF--CE 411
Query: 464 EAT-LADLLGEEAASSVVVKLANDGSGIGAALLAASHSQ 501
T + D L + + ++L+ DGSG GAA +AAS ++
Sbjct: 412 RMTDMVDKL-KPKNTRFCLRLSEDGSGKGAAAIAASCTR 449
>5HFU-A nrPDB
Length = 923
Score = 273 bits (697), Expect = 2e-73, Method: Compositional matrix adjust.
Identities = 175/461 (37%), Positives = 261/461 (56%), Gaps = 33/461 (7%)
Query: 49 IEEVEQ-----RFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISYVDNLPTGDE 101
+++V+Q R S T L I+ +EME+GL A H A +KML ++V + P G E
Sbjct: 25 VQKVDQYLYHMRLSDETLL--EISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 82
Query: 102 HGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELES 161
HG F ALDLGGTNFRV+ V++ + V + + AIP +M G+ +LFD IA L +
Sbjct: 83 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 142
Query: 162 FV-KTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELS 220
F+ K + +D LP LGFTFSFP HQT + L+ WTKGF +G G DVVA +
Sbjct: 143 FMDKLQIKDKKLP------LGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIR 196
Query: 221 RAMERQG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTG 279
+A++R+G D+ + A+VNDTVGT+ Y D++ +I+GTG+NA Y+E I G
Sbjct: 197 KAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG 256
Query: 280 LLPRSGNMVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVR 336
G M INMEWG F + R+++D +D SLNPG+Q++EKMISGMY+GE+VR
Sbjct: 257 ---DEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVR 313
Query: 337 RILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTS 396
IL+K+A + LFG + +L T D+S + + K ++ LG+ D +
Sbjct: 314 LILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMR--LGL-DPT 370
Query: 397 LEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHY 456
E T +C +V+ R A L AA + +L+++ ++ G ++ R+ I +DG +Y+ +
Sbjct: 371 QEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENK----GEERLRSTIGVDGSVYKKH 426
Query: 457 KKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAA 497
F L T+ L+ V + DGSG GAA++ A
Sbjct: 427 PHFAKRLHKTVRRLV---PGCDVRFLRSEDGSGKGAAMVTA 464
Score = 261 bits (667), Expect = 5e-70, Method: Compositional matrix adjust.
Identities = 169/440 (38%), Positives = 231/440 (52%), Gaps = 36/440 (8%)
Query: 70 MVEEMERGLRADPHA--PLKMLISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREK 127
M EMERGL + HA P+KML +YV P G E G F ALDLGGTNFRV+ V++ +
Sbjct: 497 MKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKW 556
Query: 128 RVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFP 187
V + AIP +M GT ELFD I + F++ G +G LGFTFSFP
Sbjct: 557 GGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMG-----MKGVSLPLGFTFSFP 611
Query: 188 VHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME-RQGLDMKVTALVNDTVGTLAGG 246
Q S+ L+KWTKGF +G GEDVV L A+ R+ D+ V A+VNDTVGT+
Sbjct: 612 CQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTC 671
Query: 247 RYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSGNMVINMEWGNFKSERLP---R 303
+ D +I+GTG+NA Y+E + G G M +NMEWG F R
Sbjct: 672 GFEDPHCEVGLIVGTGSNACYMEEMRNVELVEG---EEGRMCVNMEWGAFGDNGCLDDFR 728
Query: 304 SDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFIL 363
+++D A+D SLNPG+Q +EKMISGMYLGEIVR IL+ LF + +L+ R I
Sbjct: 729 TEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIF 788
Query: 364 RTPDMSAMHHDT------SHDLKHLGAKLKDILGVADTSLEARYITLHVCDLVAERGARL 417
T +S + D L+HLG +++ + I VC +VA R A+L
Sbjct: 789 ETKFLSQIESDCLALLQVRAILQHLG---------LESTCDDSIIVKEVCTVVARRAAQL 839
Query: 418 AAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCLEATLADLLGEEAAS 477
AG+ ++ ++ +R G + + +DG LY+ + F + T+ DL
Sbjct: 840 CGAGMAAVVDRIRENR----GLDALKVTVGVDGTLYKLHPHFAKVMHETVKDL---APKC 892
Query: 478 SVVVKLANDGSGIGAALLAA 497
V + DGSG GAAL+ A
Sbjct: 893 DVSFLQSEDGSGKGAALITA 912
>4FOI-A nrPDB
Length = 917
Score = 271 bits (694), Expect = 4e-73, Method: Compositional matrix adjust.
Identities = 181/469 (38%), Positives = 249/469 (53%), Gaps = 30/469 (6%)
Query: 35 REAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISY 92
R AE+ R+ IEE F +L + M EME GLR H A +KML S+
Sbjct: 462 RLAEQHRQ------IEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSF 515
Query: 93 VDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELF 152
V P G E+G F ALDLGGTNFRV+ V++ +KR V + AIP +M GT ELF
Sbjct: 516 VRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELF 575
Query: 153 DFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVG 212
D I + + F+ D+ +G + LGFTFSFP QTS+ +G LI WTKGF VG
Sbjct: 576 DHIVSCISDFL-----DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVG 630
Query: 213 EDVVAELSRAME-RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHA 271
DVV L A++ R+ D+ V A+VNDTVGT+ Y + +I+GTG+NA Y+E
Sbjct: 631 HDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEM 690
Query: 272 NAIPKWTGLLPRSGNMVINMEWGNFKSERL---PRSDYDNALDFESLNPGEQIYEKMISG 328
+ G G M INMEWG F R+ YD +D SLN G+Q YEKMISG
Sbjct: 691 KNVEMVEG---DQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISG 747
Query: 329 MYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKD 388
MYLGEIVR IL+ LF + L+ R I T +S + D L + A L+
Sbjct: 748 MYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLA-LLQVRAILQQ 806
Query: 389 ILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIAL 448
LG+ +++ + + VC +V+ R A+L AG+ ++ K+ +R G + + +
Sbjct: 807 -LGL-NSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENR----GLDRLNVTVGV 860
Query: 449 DGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAA 497
DG LY+ + F + T+ +L +V L+ DGSG GAAL+ A
Sbjct: 861 DGTLYKLHPHFSRIMHQTVKEL---SPKCNVSFLLSEDGSGKGAALITA 906
Score = 256 bits (655), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 165/435 (37%), Positives = 247/435 (56%), Gaps = 30/435 (6%)
Query: 72 EEMERGLRAD--PHAPLKMLISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRV 129
+EM+ GL D P A +KML ++V ++P G E G F ALDLGG++FR++RVQ+ + +
Sbjct: 45 KEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQN 104
Query: 130 VSQQYEEVAIPPHLMVGTSMELFDFIAAELESFV-KTEGEDFHLPEGRQRELGFTFSFPV 188
V + E P +++ G+ +LFD +A L F+ K + +D LP +GFTFSFP
Sbjct: 105 VHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLP------VGFTFSFPC 158
Query: 189 HQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQG-LDMKVTALVNDTVGTLAGGR 247
Q+ I LI WTK F +G G DVV L++A++++G D + A+VNDTVGT+
Sbjct: 159 QQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCG 218
Query: 248 YVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSGNMVINMEWGNFKSE---RLPRS 304
Y D +I+GTGTNA Y+E I G G M IN EWG F + R+
Sbjct: 219 YDDQHCEVGLIIGTGTNACYMEELRHIDLVEG---DEGRMCINTEWGAFGDDGSLEDIRT 275
Query: 305 DYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILR 364
++D +D SLNPG+Q++EKM+SGMYLGE+VR IL+K+A + LF + +L R
Sbjct: 276 EFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFN 335
Query: 365 TPDMSAMHHDTS--HDLKHLGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAGI 422
T D+SA+ + H+ K + + LGV + + + HVC +V+ R A L AA +
Sbjct: 336 TSDVSAIEKNKEGLHNAKEILTR----LGVEPSDDDCVSVQ-HVCTIVSFRSANLVAATL 390
Query: 423 YGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCLEATLADLLGEEAASSVVVK 482
IL +L RD + G+ + RT + ++G LY+ + ++ TL L+ + S V
Sbjct: 391 GAILNRL-RD---NKGTPRLRTTVGVNGSLYKTHPQYSRRFHKTLRRLVPD---SDVRFL 443
Query: 483 LANDGSGIGAALLAA 497
L+ GSG GAA++ A
Sbjct: 444 LSESGSGKGAAMVTA 458
>1BG3-A nrPDB
Length = 918
Score = 271 bits (693), Expect = 5e-73, Method: Compositional matrix adjust.
Identities = 177/469 (37%), Positives = 252/469 (53%), Gaps = 30/469 (6%)
Query: 35 REAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISY 92
R AE+ R+ IEE F L + + EME GLR + + A +KML S+
Sbjct: 462 RLAEQHRQ------IEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSF 515
Query: 93 VDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELF 152
V ++P G EHG F ALDLGGTNFRV+ V++ +KR V + +IP +M GT ELF
Sbjct: 516 VRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELF 575
Query: 153 DFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVG 212
D I + + F+ D+ +G + LGFTFSFP HQT++ G LI WTKGF G
Sbjct: 576 DHIVSCISDFL-----DYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEG 630
Query: 213 EDVVAELSRAME-RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHA 271
DV + L A++ R+ D+ V A+VNDTVGT+ Y + +I+GTGTNA Y+E
Sbjct: 631 HDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEM 690
Query: 272 NAIPKWTGLLPRSGNMVINMEWGNFKSERL---PRSDYDNALDFESLNPGEQIYEKMISG 328
+ G G M INMEWG F R+D+D +D SLN G+Q +EKMISG
Sbjct: 691 KNVEMVEG---NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISG 747
Query: 329 MYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKD 388
MYLGEIVR IL+ LF + L+ R I T +S + D L + A L+
Sbjct: 748 MYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLA-LLQVRAILQQ 806
Query: 389 ILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIAL 448
LG+ +++ + + VC +V++R A+L AG+ +++K+ +R G + +
Sbjct: 807 -LGL-NSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENR----GLDHLNVTVGV 860
Query: 449 DGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAA 497
DG LY+ + F + T+ +L +V L+ DGSG GAAL+ A
Sbjct: 861 DGTLYKLHPHFSRIMHQTVKEL---SPKCTVSFLLSEDGSGKGAALITA 906
Score = 255 bits (652), Expect = 3e-68, Method: Compositional matrix adjust.
Identities = 163/435 (37%), Positives = 246/435 (56%), Gaps = 30/435 (6%)
Query: 72 EEMERGLRAD--PHAPLKMLISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRV 129
+EM+ GL D P A +KML ++V ++P G E G F ALDLGG++FR++RVQ+ + +
Sbjct: 45 KEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQN 104
Query: 130 VSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEGEDFH-LPEGRQRELGFTFSFPV 188
VS + E P +++ G+ +LFD +A L F++ + LP +GFTFSFP
Sbjct: 105 VSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKKIKDKKLP------VGFTFSFPC 158
Query: 189 HQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQG-LDMKVTALVNDTVGTLAGGR 247
Q+ I LI WTK F +G G DVV L++A++++G D + A+VNDTVGT+
Sbjct: 159 RQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCG 218
Query: 248 YVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSGNMVINMEWGNFKSE---RLPRS 304
Y D +I+GTGTNA Y+E I G G M IN EWG F + R+
Sbjct: 219 YDDQQCEVGLIIGTGTNACYMEELRHIDLVEG---DEGRMCINTEWGAFGDDGSLEDIRT 275
Query: 305 DYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILR 364
++D LD SLNPG+Q++EKM+SGMY+GE+VR IL+K+A + LF + +L R
Sbjct: 276 EFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFN 335
Query: 365 TPDMSAMHHDTS--HDLKHLGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAGI 422
T D+SA+ D + K + + LGV + ++ + H+C +V+ R A L AA +
Sbjct: 336 TSDVSAIEKDKEGIQNAKEILTR----LGVEPSDVDCVSVQ-HICTIVSFRSANLVAATL 390
Query: 423 YGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCLEATLADLLGEEAASSVVVK 482
IL +L RD + G+ + RT + +DG LY+ + ++ TL L+ + S V
Sbjct: 391 GAILNRL-RD---NKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPD---SDVRFL 443
Query: 483 LANDGSGIGAALLAA 497
L+ G+G GAA++ A
Sbjct: 444 LSESGTGKGAAMVTA 458
>3O1W-A nrPDB
Length = 485
Score = 265 bits (676), Expect = 4e-71, Method: Compositional matrix adjust.
Identities = 167/461 (36%), Positives = 237/461 (51%), Gaps = 31/461 (6%)
Query: 49 IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYAL 108
I +E F+ + +R I + E+++GL + + M+ +V PTG E G F AL
Sbjct: 27 IHGLETLFTVSSEKMRSIVKHFISELDKGL-SKKGGNIPMIPGWVVEYPTGKETGDFLAL 85
Query: 109 DLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEGE 168
DLGGTN RV+ V+LGG +Q + +P HL GTS +L+ FIA L+ FV
Sbjct: 86 DLGGTNLRVVLVKLGGNHDFDTTQN--KYRLPDHLRTGTSEQLWSFIAKCLKEFV----- 138
Query: 169 DFHLPEGRQREL--GFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ 226
D P+G L GFTFS+P Q I+SG L +WTKGF I G G DVV L +E+
Sbjct: 139 DEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL 198
Query: 227 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPR--- 283
+ + V AL+NDT GTL Y D +I+GTG N AY + + I K GLLP
Sbjct: 199 NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIG 258
Query: 284 -SGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 340
M IN E+G+F +E LPR+ YD +D ES PG+Q +EKM SG YLGEI+R +LL
Sbjct: 259 PDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLL 318
Query: 341 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 400
L +F D +KL++ +++ T S + D +L+ K L + T +E +
Sbjct: 319 DLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERK 378
Query: 401 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 460
I + +LV R ARL G+ I K G + IA DG ++ Y ++
Sbjct: 379 LIR-KLAELVGTRAARLTVCGVSAICDKRGY----------KTAHIAADGSVFNRYPGYK 427
Query: 461 TCLEATLADLLGEEAAS----SVVVKLANDGSGIGAALLAA 497
L D+ + + + A DGSG+GAA++A
Sbjct: 428 EKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIAC 468
>3HM8-A nrPDB
Length = 445
Score = 258 bits (660), Expect = 3e-69, Method: Compositional matrix adjust.
Identities = 177/465 (38%), Positives = 258/465 (55%), Gaps = 33/465 (7%)
Query: 48 VIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYA 107
++EE F L + M + M +GLR + + L+ML ++V P G E G F A
Sbjct: 5 LLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASS-LRMLPTFVRATPDGSERGDFLA 63
Query: 108 LDLGGTNFRV--IRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKT 165
LDLGGTNFRV +RV G ++ S+ Y +IP + G+ +LFD I + F +
Sbjct: 64 LDLGGTNFRVLLVRVTTG---VQITSEIY---SIPETVAQGSGQQLFDHIVDCIVDFQQK 117
Query: 166 EGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAM-E 224
+G G+ LGFTFSFP Q + G L+ WTKGF + G+DVV+ L A+
Sbjct: 118 QG-----LSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITR 172
Query: 225 RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS 284
RQ +++ V A+VNDTVGT+ Y D +I+GTGTNA Y+E + G+ S
Sbjct: 173 RQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNV---AGVPGDS 229
Query: 285 GNMVINMEWGNFK---SERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLK 341
G M INMEWG F S + + +D ++D S+NPG+Q +EKMISGMYLGEIVR ILL
Sbjct: 230 GRMCINMEWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLH 289
Query: 342 LAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARY 401
L LF +L+ R I +T +S + D S L+ + A L+D LG+ TS +A
Sbjct: 290 LTSLGVLFRGQQIQRLQTRDIFKTKFLSEIESD-SLALRQVRAILED-LGLPLTSDDA-L 346
Query: 402 ITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRT 461
+ L VC V++R A+L AG+ +++K+ +R G ++ + +DG LY+ + +F +
Sbjct: 347 MVLEVCQAVSQRAAQLCGAGVAAVVEKIRENR----GLEELAVSVGVDGTLYKLHPRFSS 402
Query: 462 CLEATLADLLGEEAASSVVVKL-ANDGSGIGAALLAASHSQYASV 505
+ AT+ +L A VV L + DGSG GAAL+ A + A +
Sbjct: 403 LVAATVREL----APRCVVTFLQSEDGSGKGAALVTAVACRLAQL 443
>3W0L-A nrPDB
Length = 458
Score = 251 bits (641), Expect = 5e-67, Method: Compositional matrix adjust.
Identities = 167/459 (36%), Positives = 249/459 (54%), Gaps = 30/459 (6%)
Query: 49 IEEVEQRFSTPTALLRGIADAMVEEMERGL--RADPHAPLKMLISYVDNLPTGDEHGLFY 106
++++ F L + M EMERGL + A +KML +YV + P G E G F
Sbjct: 9 VDQILSEFHLQEEDLHVLMCRMQAEMERGLHLETNEEASVKMLPTYVRSTPDGSEVGDFL 68
Query: 107 ALDLGGTNFRVIRVQLG----GREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESF 162
ALDLGGTNFRV+ V++G G+ K V +++ +IP M GT+ LFD+IA + +
Sbjct: 69 ALDLGGTNFRVMLVKVGEDLEGQWK--VETKHKMYSIPVDAMTGTAEMLFDYIAECISDY 126
Query: 163 VKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRA 222
+ + + ++ LGFTFSFPV I G L+ WTKGF +G G +VV L A
Sbjct: 127 LDQQN-----MKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDA 181
Query: 223 MERQG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLL 281
++R+G +M V A+VNDTV T+ Y D+ +I+GTG NA Y+E + + G
Sbjct: 182 IKRRGDFEMDVVAMVNDTVATMISCYYEDHHCEVGLIVGTGCNACYMEEMSNVELVEG-- 239
Query: 282 PRSGNMVINMEWGNF-KSERLP--RSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRI 338
G M +N EWG F + L R +YD +D SLNPG+Q+YEKMI G Y+GE+VR +
Sbjct: 240 -EEGRMCVNTEWGAFGDTGELEDFRLEYDRVVDEASLNPGQQLYEKMIGGKYMGELVRLV 298
Query: 339 LLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLE 398
L+K+ ++ LFG KL+ R T +S + DTS D K L+ LGV T +
Sbjct: 299 LIKMVNENLLFGGESSEKLKTRGAFETQFVSQIEADTS-DFKQTLNILR-TLGVQATIGD 356
Query: 399 ARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKK 458
+ L C+ V+ R A + +AG+ GIL ++ + R + R + +DG +Y+ +
Sbjct: 357 CHAVRL-ACESVSTRAAIMCSAGLAGILNRMRQSR----REELLRITVGVDGSVYKLHPS 411
Query: 459 FRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAA 497
F+ AT+ L + + + +GSG GAAL++A
Sbjct: 412 FKDKFHATVLKLT---SGCEITFIQSEEGSGRGAALISA 447
>1IG8-A nrPDB
Length = 486
Score = 247 bits (630), Expect = 9e-66, Method: Compositional matrix adjust.
Identities = 153/439 (34%), Positives = 227/439 (51%), Gaps = 30/439 (6%)
Query: 49 IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYAL 108
IE E+ F+ PT L+ + + E+E+GL + + M+ +V + PTG E G F A+
Sbjct: 27 IENFEKIFTVPTETLQAVTKHFISELEKGL-SKKGGNIPMIPGWVMDFPTGKESGDFLAI 85
Query: 109 DLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSM--ELFDFIAAELESFVKTE 166
DLGGTN RV+ V+LGG +Q + P M T EL++FIA L++F+
Sbjct: 86 DLGGTNLRVVLVKLGGDRTFDTTQSKYRL---PDAMRTTQNPDELWEFIADSLKAFI--- 139
Query: 167 GEDFHLPEGRQRE--LGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME 224
D P+G LGFTFSFP Q I+ G L +WTKGF I DVV L + +
Sbjct: 140 --DEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQIT 197
Query: 225 RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLL--- 281
++ + ++V AL+NDT GTL Y D + VI GTG N AY + + I K G L
Sbjct: 198 KRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDD 257
Query: 282 -PRSGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRI 338
P S M IN E+G+F +E LPR+ YD +D ES PG+Q +EKM SG YLGEI+R
Sbjct: 258 IPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLA 317
Query: 339 LLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLE 398
L+ + +F + +K ++ F++ T + + D +L+ ++ G+ +T+++
Sbjct: 318 LMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGI-NTTVQ 376
Query: 399 ARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKK 458
R + + +L+ R ARL+ GI I +K G + IA DG +Y Y
Sbjct: 377 ERKLIRRLSELIGARAARLSVCGIAAICQKRGY----------KTGHIAADGSVYNRYPG 426
Query: 459 FRTCLEATLADLLGEEAAS 477
F+ L D+ G S
Sbjct: 427 FKEKAANALKDIYGWTQTS 445
>4DCH-A nrPDB
Length = 473
Score = 238 bits (607), Expect = 5e-63, Method: Compositional matrix adjust.
Identities = 167/478 (34%), Positives = 254/478 (53%), Gaps = 29/478 (6%)
Query: 39 EERRRRAAAVIEEVEQ---RFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISYV 93
++R R AA E+VEQ F L+ + M +EM+RGLR + H A +KML +YV
Sbjct: 3 DDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYV 62
Query: 94 DNLPTGDEHGLFYALDLGGTNFRVIRVQLGGRE--KRVVSQQYEEVAIPPHLMVGTSMEL 151
+ P G E G F +LDLGGTNFRV+ V++G E + V +++ +IP M GT+ L
Sbjct: 63 RSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEML 122
Query: 152 FDFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTV 211
FD+I+ + F+ D H + ++ LGFTFSFPV I G L+ WTKGF +G
Sbjct: 123 FDYISECISDFL-----DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAE 177
Query: 212 GEDVVAELSRAMERQG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEH 270
G +VV L A++R+G +M V A+VNDTV T+ Y D+ +I+GTG NA Y+E
Sbjct: 178 GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEE 237
Query: 271 ANAIPKWTGLLPRSGNMVINMEWGNF-KSERLPRS--DYDNALDFESLNPGEQIYEKMIS 327
+ G G M +N EWG F S L +YD +D S NPG+Q+YEK+I
Sbjct: 238 MQNVELVEG---DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIG 294
Query: 328 GMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLK 387
G Y+GE+VR +LL+L + LF +L R T +S + DT D K + +
Sbjct: 295 GKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTG-DRKQI-YNIL 352
Query: 388 DILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIA 447
LG+ ++ + I C+ V+ R A + +AG+ G++ ++ R R +
Sbjct: 353 STLGLRPSTTDCD-IVRRACESVSTRAAHMCSAGLAGVINRMRESR----SEDVMRITVG 407
Query: 448 LDGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASV 505
+DG +Y+ + F+ A++ L + + + +GSG GAAL++A + A +
Sbjct: 408 VDGSVYKLHPSFKERFHASVRRLT---PSCEITFIESEEGSGRGAALVSAVACKKACM 462
>3B8A-X nrPDB
Length = 485
Score = 234 bits (596), Expect = 8e-62, Method: Compositional matrix adjust.
Identities = 163/460 (35%), Positives = 240/460 (52%), Gaps = 29/460 (6%)
Query: 49 IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYAL 108
I ++E F+ + LR + ++E+ +GL + M+ +V PTG E G + A+
Sbjct: 27 IHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK-GGNIPMIPGWVMEFPTGKESGNYLAI 85
Query: 109 DLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSM--ELFDFIAAELESFVKTE 166
DLGGTN RV+ V+L G +Q ++ PH M T EL+ FIA L+ F+ E
Sbjct: 86 DLGGTNLRVVLVKLSGNHTFDTTQSKYKL---PHDMRTTKHQEELWSFIADSLKDFM-VE 141
Query: 167 GEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ 226
E + + LGFTFS+P Q I+ G L +WTKGF I G DVV L + ++
Sbjct: 142 QELLNTKD--TLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR 199
Query: 227 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLL----P 282
L +++ AL+NDTVGTL Y D + VI GTG N A+ + + I K G L P
Sbjct: 200 ELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIP 259
Query: 283 RSGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 340
+ M IN E+G+F +E LPR+ YD A+D +S PG+Q +EKM SG YLGE++R +LL
Sbjct: 260 SNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLL 319
Query: 341 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 400
+L + D +KL+Q +I+ T + + D +L+ + GV T+L R
Sbjct: 320 ELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVK-TTLPER 378
Query: 401 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 460
+ +C+L+ R ARLA GI I +K G + IA DG +Y Y F+
Sbjct: 379 KLIRRLCELIGTRAARLAVCGIAAICQKRGY----------KTGHIAADGSVYNKYPGFK 428
Query: 461 TCLEATLADLL---GEEAASSVVVKLANDGSGIGAALLAA 497
L D+ G+ + + + A DGSG GAA++AA
Sbjct: 429 EAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAA 468
>2YHX-A nrPDB
Length = 457
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 47/218 (21%), Positives = 82/218 (37%), Gaps = 22/218 (10%)
Query: 56 FSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYALDLGGTNF 115
F P +L+ + + + + P M+ +V +G + G F A+ +GG +
Sbjct: 16 FIVPPXILQAVVSILTTRXDDXDSSAASIP--MVPGWVLKQVSGAQAGSFLAIVMGGGDL 73
Query: 116 RVIRVQLGGREK------RVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEGED 169
VI + L GR++ R ++ AIP L + + S +
Sbjct: 74 EVILISLAGRQESSIXASRSLAAAMSTTAIPSDLWGNXAX------SNAAFSSXEFSSXA 127
Query: 170 FHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQGLD 229
+P LGFTF + + G + FS+ +++ + A G
Sbjct: 128 GSVP------LGFTFXEAGAKEXVIKGQITXQAXAFSLAXL--XKLISAMXNAXFPAGDX 179
Query: 230 MKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAY 267
A + D+ G L Y D + +I G+G NAAY
Sbjct: 180 XXSVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAY 217
>1HKG-A nrPDB
Length = 457
Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 42/188 (22%), Positives = 71/188 (37%), Gaps = 20/188 (10%)
Query: 86 LKMLISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREK------RVVSQQYEEVAI 139
+ M+ +V G + G F A+ +GG + VI + L G ++ R ++ AI
Sbjct: 44 IPMVPGWVLKQVXGSQAGSFLAIVMGGGDLEVILIXLAGYQESSIXASRSLAASMXTTAI 103
Query: 140 PPHLMVGTSMELFDFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLI 199
P L + + S + +P LGFTF + + G +
Sbjct: 104 PSDLWGNXAX------SNAAFSSXEFSSXAGSVP------LGFTFXEAGAKEXVIKGQIT 151
Query: 200 KWTKGFSINGTVGEDVVAELSRAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVIL 259
FS+ +++ + A G A + D+ G L Y D + +I
Sbjct: 152 XQAXAFSLAXL--XKLISAMXNAXFPAGDXXXXVADIXDSHGILXXVNYTDAXIKMGIIF 209
Query: 260 GTGTNAAY 267
G+G NAAY
Sbjct: 210 GSGVNAAY 217
>4OVD-A nrPDB
Length = 564
Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 11/66 (16%)
Query: 298 SERLPRSDYDNALDFESLNPGEQIYEKMISGMY-LGEIVRRILLKLAHDASLFGD----V 352
S LP + DN +D+ESLN K++S +Y G + + I + D +LFG
Sbjct: 265 SYPLPDFESDNGVDYESLN------LKLVSSIYEPGSVFKVITTSIGVDNNLFGPNSTFN 318
Query: 353 VPTKLE 358
+PT+L+
Sbjct: 319 IPTELQ 324
>5ZEP-H nrPDB
Length = 151
Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 22 GVAVVVSRRRRSKREAEEERRRRAAAVIEEVEQRFSTPTALLRGIAD 68
G+A+V SR ++R+AEE RR R + VI ++E TA L G+ D
Sbjct: 34 GLAIVASRG--AERQAEEIRRARESKVIRDIEHANELKTA-LEGLGD 77
>2IZO-A nrPDB
Length = 346
Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 38/55 (69%), Gaps = 5/55 (9%)
Query: 27 VSRRRRSKREAEEE-RRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRA 80
+ RRR++K EAE + R ++ IEE+ +++S A+LR +++ MVEE ++ LRA
Sbjct: 88 LERRRKAKEEAERKLERAKSEGKIEEL-RKYSQ--AILR-LSNIMVEESKKLLRA 138
>4B2T-A nrPDB
Length = 556
Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Query: 57 STPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYALDLGGTNFR 116
++ + +LRG D M +EMER L D +K ++ +P G + AL + N+
Sbjct: 371 TSASVILRGANDFMCDEMERSLH-DALCVVKRVLESKSVVPGG--GAVEAALSIYLENY- 426
Query: 117 VIRVQLGGREKRVVSQQYEEV-AIPPHLMVGTSMELFDFIAAELESF 162
+G RE+ +++ + IP L V + + D + A+L +F
Sbjct: 427 --ATSMGSREQLAIAEFARSLPVIPNTLAVNAAQDSTDLV-AKLRAF 470
>6FPX-A nrPDB
Length = 192
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
Query: 382 LGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDR 433
A++ +I+ D EAR +++ + G+RL Y I+K++GRDR
Sbjct: 145 FSAEISEIVSHMDHGSEAR----DGMEMMYDEGSRLCTLINYAIMKRIGRDR 192
>6D7W-A nrPDB
Length = 416
Score = 28.9 bits (63), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 405 HVCDLVAERGARLAAAGIYGIL 426
H CD +A RGA+ A G +GIL
Sbjct: 257 HECDALAHRGAQRVALGGFGIL 278
>5HFZ-A nrPDB
Length = 170
Score = 28.9 bits (63), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
Query: 382 LGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDR 433
A++ +I+ D EAR +++ + G+RL Y I+K++GRDR
Sbjct: 123 FSAEISEIVSHMDHGSEAR----DGMEMMYDEGSRLCTLINYAIMKRIGRDR 170
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
5ZQT-A nrPDB 644 0.0
1BG3-A nrPDB 627 e-180
4FOI-A nrPDB 627 e-180
4QS9-A nrPDB 608 e-174
5HFU-A nrPDB 593 e-170
3O1W-A nrPDB 584 e-167
3W0L-A nrPDB 584 e-167
4DCH-A nrPDB 576 e-165
3HM8-A nrPDB 568 e-162
1IG8-A nrPDB 567 e-162
3B8A-X nrPDB 558 e-159
1BDG-A nrPDB 548 e-156
Sequences not found previously or not previously below threshold:
2YHX-A nrPDB 139 3e-33
1HKG-A nrPDB 135 6e-32
1Q1R-A nrPDB 29 4.9
1E19-A nrPDB 29 6.0
6MU0-A nrPDB 29 6.1
2WD5-A nrPDB 28 7.9
2BWY-A nrPDB 28 8.0
1Q5D-A nrPDB 28 9.7
>5ZQT-A nrPDB
Length = 473
Score = 644 bits (1661), Expect = 0.0, Method: Composition-based stats.
Identities = 463/466 (99%), Positives = 463/466 (99%)
Query: 41 RRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGD 100
R AAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGD
Sbjct: 8 RIPMAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGD 67
Query: 101 EHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELE 160
EHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELE
Sbjct: 68 EHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELE 127
Query: 161 SFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELS 220
SFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELS
Sbjct: 128 SFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELS 187
Query: 221 RAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGL 280
RAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGL
Sbjct: 188 RAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGL 247
Query: 281 LPRSGNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 340
LPRSGNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL
Sbjct: 248 LPRSGNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 307
Query: 341 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 400
KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR
Sbjct: 308 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 367
Query: 401 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 460
YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR
Sbjct: 368 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 427
Query: 461 TCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASVE 506
TCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASVE
Sbjct: 428 TCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASVE 473
>1BG3-A nrPDB
Length = 918
Score = 627 bits (1618), Expect = e-180, Method: Composition-based stats.
Identities = 177/474 (37%), Positives = 253/474 (53%), Gaps = 30/474 (6%)
Query: 35 REAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISY 92
R AE+ R+ IEE F L + + EME GLR + + A +KML S+
Sbjct: 462 RLAEQHRQ------IEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSF 515
Query: 93 VDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELF 152
V ++P G EHG F ALDLGGTNFRV+ V++ +KR V + +IP +M GT ELF
Sbjct: 516 VRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELF 575
Query: 153 DFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVG 212
D I + + F+ D+ +G + LGFTFSFP HQT++ G LI WTKGF G
Sbjct: 576 DHIVSCISDFL-----DYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEG 630
Query: 213 EDVVAELSRAMERQ-GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHA 271
DV + L A++R+ D+ V A+VNDTVGT+ Y + +I+GTGTNA Y+E
Sbjct: 631 HDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEM 690
Query: 272 NAIPKWTGLLPRSGNMVINMEWGNFKSERL---PRSDYDNALDFESLNPGEQIYEKMISG 328
+ G G M INMEWG F R+D+D +D SLN G+Q +EKMISG
Sbjct: 691 KNVEMVEG---NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISG 747
Query: 329 MYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKD 388
MYLGEIVR IL+ LF + L+ R I T +S + D L + A L+
Sbjct: 748 MYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLA-LLQVRAILQQ 806
Query: 389 ILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIAL 448
LG+ +++ + + VC +V++R A+L AG+ +++K+ +R G + +
Sbjct: 807 -LGL-NSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENR----GLDHLNVTVGV 860
Query: 449 DGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQY 502
DG LY+ + F + T+ +L +V L+ DGSG GAAL+ A +
Sbjct: 861 DGTLYKLHPHFSRIMHQTVKEL---SPKCTVSFLLSEDGSGKGAALITAVGVRL 911
Score = 494 bits (1271), Expect = e-140, Method: Composition-based stats.
Identities = 163/463 (35%), Positives = 249/463 (53%), Gaps = 24/463 (5%)
Query: 48 VIEEVEQRFSTPTALLRGIADAMVEEMERGLRAD--PHAPLKMLISYVDNLPTGDEHGLF 105
I++ +L I +EM+ GL D P A +KML ++V ++P G E G F
Sbjct: 21 KIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDF 80
Query: 106 YALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKT 165
ALDLGG++FR++RVQ+ + + VS + E P +++ G+ +LFD +A L F++
Sbjct: 81 IALDLGGSSFRILRVQVNHEKNQNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEK 140
Query: 166 EGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMER 225
+ +GFTFSFP Q+ I LI WTK F +G G DVV L++A+++
Sbjct: 141 KKIKDKK-----LPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKK 195
Query: 226 QG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS 284
+G D + A+VNDTVGT+ Y D +I+GTGTNA Y+E I G
Sbjct: 196 RGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEG---DE 252
Query: 285 GNMVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLK 341
G M IN EWG F + R+++D LD SLNPG+Q++EKM+SGMY+GE+VR IL+K
Sbjct: 253 GRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVK 312
Query: 342 LAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARY 401
+A + LF + +L R T D+SA+ D +++ L LGV + ++
Sbjct: 313 MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKDK-EGIQNAKEILTR-LGVEPSDVDC-V 369
Query: 402 ITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRT 461
H+C +V+ R A L AA + IL +L ++ G+ + RT + +DG LY+ + ++
Sbjct: 370 SVQHICTIVSFRSANLVAATLGAILNRLRDNK----GTPRLRTTVGVDGSLYKMHPQYSR 425
Query: 462 CLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYAS 504
TL L+ S V L+ G+G GAA++ A + A
Sbjct: 426 RFHKTLRRLV---PDSDVRFLLSESGTGKGAAMVTAVAYRLAE 465
>4FOI-A nrPDB
Length = 917
Score = 627 bits (1617), Expect = e-180, Method: Composition-based stats.
Identities = 181/474 (38%), Positives = 250/474 (52%), Gaps = 30/474 (6%)
Query: 35 REAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISY 92
R AE+ R+ IEE F +L + M EME GLR H A +KML S+
Sbjct: 462 RLAEQHRQ------IEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSF 515
Query: 93 VDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELF 152
V P G E+G F ALDLGGTNFRV+ V++ +KR V + AIP +M GT ELF
Sbjct: 516 VRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELF 575
Query: 153 DFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVG 212
D I + + F+ D+ +G + LGFTFSFP QTS+ +G LI WTKGF VG
Sbjct: 576 DHIVSCISDFL-----DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVG 630
Query: 213 EDVVAELSRAMERQ-GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHA 271
DVV L A++R+ D+ V A+VNDTVGT+ Y + +I+GTG+NA Y+E
Sbjct: 631 HDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEM 690
Query: 272 NAIPKWTGLLPRSGNMVINMEWGNFKSERL---PRSDYDNALDFESLNPGEQIYEKMISG 328
+ G G M INMEWG F R+ YD +D SLN G+Q YEKMISG
Sbjct: 691 KNVEMVEG---DQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISG 747
Query: 329 MYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKD 388
MYLGEIVR IL+ LF + L+ R I T +S + D L + A L+
Sbjct: 748 MYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLA-LLQVRAILQQ 806
Query: 389 ILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIAL 448
LG+ +++ + + VC +V+ R A+L AG+ ++ K+ +R G + + +
Sbjct: 807 -LGL-NSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENR----GLDRLNVTVGV 860
Query: 449 DGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQY 502
DG LY+ + F + T+ +L +V L+ DGSG GAAL+ A +
Sbjct: 861 DGTLYKLHPHFSRIMHQTVKEL---SPKCNVSFLLSEDGSGKGAALITAVGVRL 911
Score = 498 bits (1282), Expect = e-141, Method: Composition-based stats.
Identities = 164/463 (35%), Positives = 247/463 (53%), Gaps = 24/463 (5%)
Query: 48 VIEEVEQRFSTPTALLRGIADAMVEEMERGLRAD--PHAPLKMLISYVDNLPTGDEHGLF 105
I++ L I +EM+ GL D P A +KML ++V ++P G E G F
Sbjct: 21 KIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 80
Query: 106 YALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKT 165
ALDLGG++FR++RVQ+ + + V + E P +++ G+ +LFD +A L F++
Sbjct: 81 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 140
Query: 166 EGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMER 225
+ ++ +GFTFSFP Q+ I LI WTK F +G G DVV L++A+++
Sbjct: 141 RK-----IKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKK 195
Query: 226 QG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS 284
+G D + A+VNDTVGT+ Y D +I+GTGTNA Y+E I G
Sbjct: 196 RGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG---DE 252
Query: 285 GNMVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLK 341
G M IN EWG F + R+++D +D SLNPG+Q++EKM+SGMYLGE+VR IL+K
Sbjct: 253 GRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVK 312
Query: 342 LAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARY 401
+A + LF + +L R T D+SA+ + L + L LGV S +
Sbjct: 313 MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEILTR-LGVE-PSDDDCV 369
Query: 402 ITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRT 461
HVC +V+ R A L AA + IL +L ++ G+ + RT + ++G LY+ + ++
Sbjct: 370 SVQHVCTIVSFRSANLVAATLGAILNRLRDNK----GTPRLRTTVGVNGSLYKTHPQYSR 425
Query: 462 CLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYAS 504
TL L+ S V L+ GSG GAA++ A + A
Sbjct: 426 RFHKTLRRLV---PDSDVRFLLSESGSGKGAAMVTAVAYRLAE 465
>4QS9-A nrPDB
Length = 474
Score = 608 bits (1567), Expect = e-174, Method: Composition-based stats.
Identities = 310/459 (67%), Positives = 376/459 (81%), Gaps = 2/459 (0%)
Query: 44 RAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHG 103
R A+++ E+ +TP + LR +ADAM EM GL +D + LKMLISYVDNLP+GDE G
Sbjct: 14 RVLAILKAFEEDCATPISKLRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKG 73
Query: 104 LFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFV 163
LFYALDLGGTNFRV+RV LGG+++RVV Q++EEV+IPPHLM G S ELF+FIA L FV
Sbjct: 74 LFYALDLGGTNFRVMRVLLGGKQERVVKQEFEEVSIPPHLMTGGSDELFNFIAEALAKFV 133
Query: 164 KTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAM 223
TE EDFHLPEGRQRELGFTF+FPV QTS+SSG+LIKWTKGFSI VG+DVV L++A+
Sbjct: 134 ATECEDFHLPEGRQRELGFTFAFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGALNKAL 193
Query: 224 ERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPR 283
ER GLDM++ ALVNDTVGTLAGGRY + DV AAVILGTGTNAAYVE A AIPKW GLLP+
Sbjct: 194 ERVGLDMRIAALVNDTVGTLAGGRYYNPDVVAAVILGTGTNAAYVERATAIPKWHGLLPK 253
Query: 284 SGNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLA 343
SG MVINMEWGNF+S LP +++D+ LDFESLNPGEQI EK+ISGMYLGEI+RR+LLK+A
Sbjct: 254 SGEMVINMEWGNFRSSHLPLTEFDHTLDFESLNPGEQILEKIISGMYLGEILRRVLLKMA 313
Query: 344 HDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYIT 403
DA+ FGD VP+KL FI+RTP MSAMH+DTS DLK +G+K+KDIL V TSL+ R +
Sbjct: 314 EDAAFFGDTVPSKLRIPFIIRTPHMSAMHNDTSPDLKIVGSKIKDILEVPTTSLKMRKVV 373
Query: 404 LHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCL 463
+ +C+++A RGARL+AAGIYGILKKLGRD + Q++VIA+DGGL+EHY +F C+
Sbjct: 374 ISLCNIIATRGARLSAAGIYGILKKLGRDTTKD--EEVQKSVIAMDGGLFEHYTQFSECM 431
Query: 464 EATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQY 502
E++L +LLG+EA+ SV V +NDGSGIGAALLAASHS Y
Sbjct: 432 ESSLKELLGDEASGSVEVTHSNDGSGIGAALLAASHSLY 470
>5HFU-A nrPDB
Length = 923
Score = 593 bits (1528), Expect = e-170, Method: Composition-based stats.
Identities = 173/473 (36%), Positives = 244/473 (51%), Gaps = 30/473 (6%)
Query: 35 REAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAP--LKMLISY 92
R A++ R R ++ + L + M EMERGL + HA +KML +Y
Sbjct: 468 RLADQHRAR------QKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTY 521
Query: 93 VDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELF 152
V P G E G F ALDLGGTNFRV+ V++ + V + AIP +M GT ELF
Sbjct: 522 VCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELF 581
Query: 153 DFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVG 212
D I + F++ + +G LGFTFSFP Q S+ L+KWTKGF +G G
Sbjct: 582 DHIVQCIADFLE-----YMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 636
Query: 213 EDVVAELSRAMERQ-GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHA 271
EDVV L A+ R+ D+ V A+VNDTVGT+ + D +I+GTG+NA Y+E
Sbjct: 637 EDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEM 696
Query: 272 NAIPKWTGLLPRSGNMVINMEWGNFKSERLP---RSDYDNALDFESLNPGEQIYEKMISG 328
+ G G M +NMEWG F R+++D A+D SLNPG+Q +EKMISG
Sbjct: 697 RNVELVEG---EEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISG 753
Query: 329 MYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKD 388
MYLGEIVR IL+ LF + +L+ R I T +S + D L + A L+
Sbjct: 754 MYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLA-LLQVRAILQH 812
Query: 389 ILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIAL 448
LG+ ++ + I VC +VA R A+L AG+ ++ ++ +R G + + +
Sbjct: 813 -LGLE-STCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENR----GLDALKVTVGV 866
Query: 449 DGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQ 501
DG LY+ + F + T+ DL V + DGSG GAAL+ A +
Sbjct: 867 DGTLYKLHPHFAKVMHETVKDL---APKCDVSFLQSEDGSGKGAALITAVACR 916
Score = 584 bits (1505), Expect = e-167, Method: Composition-based stats.
Identities = 168/462 (36%), Positives = 255/462 (55%), Gaps = 24/462 (5%)
Query: 48 VIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISYVDNLPTGDEHGLF 105
+++ L I+ +EME+GL A H A +KML ++V + P G EHG F
Sbjct: 27 KVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEF 86
Query: 106 YALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKT 165
ALDLGGTNFRV+ V++ + V + + AIP +M G+ +LFD IA L +F+
Sbjct: 87 LALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFM-- 144
Query: 166 EGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMER 225
D + ++ LGFTFSFP HQT + L+ WTKGF +G G DVVA + +A++R
Sbjct: 145 ---DKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQR 201
Query: 226 QG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRS 284
+G D+ + A+VNDTVGT+ Y D++ +I+GTG+NA Y+E I G
Sbjct: 202 RGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG---DE 258
Query: 285 GNMVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLK 341
G M INMEWG F + R+++D +D SLNPG+Q++EKMISGMY+GE+VR IL+K
Sbjct: 259 GRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVK 318
Query: 342 LAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARY 401
+A + LFG + +L T D+S + + K ++ LG+ D + E
Sbjct: 319 MAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMR--LGL-DPTQEDCV 375
Query: 402 ITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRT 461
T +C +V+ R A L AA + +L+++ ++ G ++ R+ I +DG +Y+ + F
Sbjct: 376 ATHRICQIVSTRSASLCAATLAAVLQRIKENK----GEERLRSTIGVDGSVYKKHPHFAK 431
Query: 462 CLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYA 503
L T+ L+ V + DGSG GAA++ A + A
Sbjct: 432 RLHKTVRRLV---PGCDVRFLRSEDGSGKGAAMVTAVAYRLA 470
>3O1W-A nrPDB
Length = 485
Score = 584 bits (1506), Expect = e-167, Method: Composition-based stats.
Identities = 167/461 (36%), Positives = 237/461 (51%), Gaps = 31/461 (6%)
Query: 49 IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYAL 108
I +E F+ + +R I + E+++GL + + M+ +V PTG E G F AL
Sbjct: 27 IHGLETLFTVSSEKMRSIVKHFISELDKGL-SKKGGNIPMIPGWVVEYPTGKETGDFLAL 85
Query: 109 DLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEGE 168
DLGGTN RV+ V+LGG +Q + +P HL GTS +L+ FIA L+ FV
Sbjct: 86 DLGGTNLRVVLVKLGGNHDFDTTQN--KYRLPDHLRTGTSEQLWSFIAKCLKEFV----- 138
Query: 169 DFHLPEGRQ--RELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ 226
D P+G LGFTFS+P Q I+SG L +WTKGF I G G DVV L +E+
Sbjct: 139 DEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL 198
Query: 227 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPR--- 283
+ + V AL+NDT GTL Y D +I+GTG N AY + + I K GLLP
Sbjct: 199 NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIG 258
Query: 284 -SGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 340
M IN E+G+F +E LPR+ YD +D ES PG+Q +EKM SG YLGEI+R +LL
Sbjct: 259 PDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLL 318
Query: 341 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 400
L +F D +KL++ +++ T S + D +L+ K L + T +E R
Sbjct: 319 DLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVE-R 377
Query: 401 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 460
+ + +LV R ARL G+ I K G + IA DG ++ Y ++
Sbjct: 378 KLIRKLAELVGTRAARLTVCGVSAICDKRGY----------KTAHIAADGSVFNRYPGYK 427
Query: 461 TCLEATLADLLGEEAAS----SVVVKLANDGSGIGAALLAA 497
L D+ + + + A DGSG+GAA++A
Sbjct: 428 EKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIAC 468
>3W0L-A nrPDB
Length = 458
Score = 584 bits (1505), Expect = e-167, Method: Composition-based stats.
Identities = 165/465 (35%), Positives = 248/465 (53%), Gaps = 26/465 (5%)
Query: 49 IEEVEQRFSTPTALLRGIADAMVEEMERGL--RADPHAPLKMLISYVDNLPTGDEHGLFY 106
++++ F L + M EMERGL + A +KML +YV + P G E G F
Sbjct: 9 VDQILSEFHLQEEDLHVLMCRMQAEMERGLHLETNEEASVKMLPTYVRSTPDGSEVGDFL 68
Query: 107 ALDLGGTNFRVIRVQLGGR--EKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVK 164
ALDLGGTNFRV+ V++G + V +++ +IP M GT+ LFD+IA + ++
Sbjct: 69 ALDLGGTNFRVMLVKVGEDLEGQWKVETKHKMYSIPVDAMTGTAEMLFDYIAECISDYLD 128
Query: 165 TEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME 224
+ + ++ LGFTFSFPV I G L+ WTKGF +G G +VV L A++
Sbjct: 129 QQN-----MKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIK 183
Query: 225 RQG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPR 283
R+G +M V A+VNDTV T+ Y D+ +I+GTG NA Y+E + + G
Sbjct: 184 RRGDFEMDVVAMVNDTVATMISCYYEDHHCEVGLIVGTGCNACYMEEMSNVELVEG---E 240
Query: 284 SGNMVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 340
G M +N EWG F R +YD +D SLNPG+Q+YEKMI G Y+GE+VR +L+
Sbjct: 241 EGRMCVNTEWGAFGDTGELEDFRLEYDRVVDEASLNPGQQLYEKMIGGKYMGELVRLVLI 300
Query: 341 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 400
K+ ++ LFG KL+ R T +S + DTS D K L+ LGV T +
Sbjct: 301 KMVNENLLFGGESSEKLKTRGAFETQFVSQIEADTS-DFKQTLNILR-TLGVQATIGDCH 358
Query: 401 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 460
+ L C+ V+ R A + +AG+ GIL ++ + R + R + +DG +Y+ + F+
Sbjct: 359 AVRL-ACESVSTRAAIMCSAGLAGILNRMRQSR----REELLRITVGVDGSVYKLHPSFK 413
Query: 461 TCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASV 505
AT+ L + + + +GSG GAAL++A + A +
Sbjct: 414 DKFHATVLKLT---SGCEITFIQSEEGSGRGAALISAVAYKMAVM 455
>4DCH-A nrPDB
Length = 473
Score = 576 bits (1484), Expect = e-165, Method: Composition-based stats.
Identities = 162/478 (33%), Positives = 250/478 (52%), Gaps = 29/478 (6%)
Query: 39 EERRRRAAAV---IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPH--APLKMLISYV 93
++R R AA +E++ F L+ + M +EM+RGLR + H A +KML +YV
Sbjct: 3 DDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYV 62
Query: 94 DNLPTGDEHGLFYALDLGGTNFRVIRVQLGGR--EKRVVSQQYEEVAIPPHLMVGTSMEL 151
+ P G E G F +LDLGGTNFRV+ V++G + V +++ +IP M GT+ L
Sbjct: 63 RSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEML 122
Query: 152 FDFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTV 211
FD+I+ + F+ D H + ++ LGFTFSFPV I G L+ WTKGF +G
Sbjct: 123 FDYISECISDFL-----DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAE 177
Query: 212 GEDVVAELSRAMERQG-LDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEH 270
G +VV L A++R+G +M V A+VNDTV T+ Y D+ +I+GTG NA Y+E
Sbjct: 178 GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEE 237
Query: 271 ANAIPKWTGLLPRSGNMVINMEWGNFKSERLP---RSDYDNALDFESLNPGEQIYEKMIS 327
+ G G M +N EWG F +YD +D S NPG+Q+YEK+I
Sbjct: 238 MQNVELVEG---DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIG 294
Query: 328 GMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLK 387
G Y+GE+VR +LL+L + LF +L R T +S + DT D K + L
Sbjct: 295 GKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDT-GDRKQIYNIL- 352
Query: 388 DILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIA 447
LG+ ++ + I C+ V+ R A + +AG+ G++ ++ R R +
Sbjct: 353 STLGLRPSTTDCD-IVRRACESVSTRAAHMCSAGLAGVINRMRESR----SEDVMRITVG 407
Query: 448 LDGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASV 505
+DG +Y+ + F+ A++ L + + + +GSG GAAL++A + A +
Sbjct: 408 VDGSVYKLHPSFKERFHASVRRLT---PSCEITFIESEEGSGRGAALVSAVACKKACM 462
>3HM8-A nrPDB
Length = 445
Score = 568 bits (1464), Expect = e-162, Method: Composition-based stats.
Identities = 169/462 (36%), Positives = 251/462 (54%), Gaps = 27/462 (5%)
Query: 48 VIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYA 107
++EE F L + M + M +GLR + + L+ML ++V P G E G F A
Sbjct: 5 LLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEA-SSLRMLPTFVRATPDGSERGDFLA 63
Query: 108 LDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEG 167
LDLGGTNFRV+ V++ V E +IP + G+ +LFD I + F + +G
Sbjct: 64 LDLGGTNFRVLLVRVTTG----VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQG 119
Query: 168 EDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ- 226
G+ LGFTFSFP Q + G L+ WTKGF + G+DVV+ L A+ R+
Sbjct: 120 -----LSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQ 174
Query: 227 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSGN 286
+++ V A+VNDTVGT+ Y D +I+GTGTNA Y+E + G+ SG
Sbjct: 175 AVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNV---AGVPGDSGR 231
Query: 287 MVINMEWGNFKSER---LPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLA 343
M INMEWG F + + + +D ++D S+NPG+Q +EKMISGMYLGEIVR ILL L
Sbjct: 232 MCINMEWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLT 291
Query: 344 HDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYIT 403
LF +L+ R I +T +S + D S L+ + A L+D LG+ TS + +
Sbjct: 292 SLGVLFRGQQIQRLQTRDIFKTKFLSEIESD-SLALRQVRAILED-LGLPLTS-DDALMV 348
Query: 404 LHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTCL 463
L VC V++R A+L AG+ +++K+ +R G ++ + +DG LY+ + +F + +
Sbjct: 349 LEVCQAVSQRAAQLCGAGVAAVVEKIRENR----GLEELAVSVGVDGTLYKLHPRFSSLV 404
Query: 464 EATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQYASV 505
AT+ +L V + DGSG GAAL+ A + A +
Sbjct: 405 AATVREL---APRCVVTFLQSEDGSGKGAALVTAVACRLAQL 443
>1IG8-A nrPDB
Length = 486
Score = 567 bits (1461), Expect = e-162, Method: Composition-based stats.
Identities = 155/472 (32%), Positives = 240/472 (50%), Gaps = 34/472 (7%)
Query: 29 RRRRSKREAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKM 88
++ ++++ + + + IE E+ F+ PT L+ + + E+E+GL + + M
Sbjct: 7 KKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGL-SKKGGNIPM 65
Query: 89 LISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTS 148
+ +V + PTG E G F A+DLGGTN RV+ V+LGG +Q + P M T
Sbjct: 66 IPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRL---PDAMRTTQ 122
Query: 149 --MELFDFIAAELESFVKTEGEDFHLPEGRQRE--LGFTFSFPVHQTSISSGTLIKWTKG 204
EL++FIA L++F+ D P+G LGFTFSFP Q I+ G L +WTKG
Sbjct: 123 NPDELWEFIADSLKAFI-----DEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKG 177
Query: 205 FSINGTVGEDVVAELSRAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTN 264
F I DVV L + + ++ + ++V AL+NDT GTL Y D + VI GTG N
Sbjct: 178 FDIPNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVN 237
Query: 265 AAYVEHANAIPKWTGLL----PRSGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPG 318
AY + + I K G L P S M IN E+G+F +E LPR+ YD +D ES PG
Sbjct: 238 GAYYDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPG 297
Query: 319 EQIYEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHD 378
+Q +EKM SG YLGEI+R L+ + +F + +K ++ F++ T + + D +
Sbjct: 298 QQTFEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFEN 357
Query: 379 LKHLGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDG 438
L+ ++ G+ +T+++ R + + +L+ R ARL+ GI I +K G
Sbjct: 358 LEDTDDLFQNEFGI-NTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGY------- 409
Query: 439 SQKQRTVIALDGGLYEHYKKFRTCLEATLADLLGEEAAS----SVVVKLAND 486
+ IA DG +Y Y F+ L D+ G S + + A D
Sbjct: 410 ---KTGHIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAED 458
>3B8A-X nrPDB
Length = 485
Score = 558 bits (1437), Expect = e-159, Method: Composition-based stats.
Identities = 163/484 (33%), Positives = 249/484 (51%), Gaps = 29/484 (5%)
Query: 29 RRRRSKREAEEERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKM 88
++ ++++ + + + I ++E F+ + LR + ++E+ +GL + M
Sbjct: 7 KKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGL-TKKGGNIPM 65
Query: 89 LISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGT- 147
+ +V PTG E G + A+DLGGTN RV+ V+L G +Q ++ PH M T
Sbjct: 66 IPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKL---PHDMRTTK 122
Query: 148 -SMELFDFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFS 206
EL+ FIA L+ F+ E E + + LGFTFS+P Q I+ G L +WTKGF
Sbjct: 123 HQEELWSFIADSLKDFM-VEQELLNTKD--TLPLGFTFSYPASQNKINEGILQRWTKGFD 179
Query: 207 INGTVGEDVVAELSRAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAA 266
I G DVV L + ++ L +++ AL+NDTVGTL Y D + VI GTG N A
Sbjct: 180 IPNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGA 239
Query: 267 YVEHANAIPKWTGLL----PRSGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPGEQ 320
+ + + I K G L P + M IN E+G+F +E LPR+ YD A+D +S PG+Q
Sbjct: 240 FYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQ 299
Query: 321 IYEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLK 380
+EKM SG YLGE++R +LL+L + D +KL+Q +I+ T + + D +L+
Sbjct: 300 AFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLE 359
Query: 381 HLGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQ 440
+ GV T+L R + +C+L+ R ARLA GI I +K G
Sbjct: 360 DTDDIFQKDFGVK-TTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGY--------- 409
Query: 441 KQRTVIALDGGLYEHYKKFRTCLEATLADLLGEE---AASSVVVKLANDGSGIGAALLAA 497
+ IA DG +Y Y F+ L D+ G + + + A DGSG GAA++AA
Sbjct: 410 -KTGHIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAA 468
Query: 498 SHSQ 501
+
Sbjct: 469 LSEK 472
>1BDG-A nrPDB
Length = 451
Score = 548 bits (1413), Expect = e-156, Method: Composition-based stats.
Identities = 166/459 (36%), Positives = 249/459 (54%), Gaps = 25/459 (5%)
Query: 48 VIEEVEQRFSTPTALLRGIADAMVEEMERGLR--ADPHAPLKMLISYVDNLPTGDEHGLF 105
+ E+ + F I D M E M GL+ + + +KM SYV P G E G F
Sbjct: 11 KVVEILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTPNGTETGNF 70
Query: 106 YALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKT 165
ALDLGGTN+RV+ V L G+ K Q+ IP M G+ ELF +IA L F++
Sbjct: 71 LALDLGGTNYRVLSVTLEGKGKSPRIQE-RTYCIPAEKMSGSGTELFKYIAETLADFLEN 129
Query: 166 EGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMER 225
G + ++ +LGFTFSFP Q ++ TL++WTKGFS +G G +V L +++
Sbjct: 130 NG-----MKDKKFDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQTELDK 184
Query: 226 QGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSG 285
+ L++K A+VNDTVGTLA D A +I+GTGTN AY+E ++ + G+ +
Sbjct: 185 RELNVKCVAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGV--KEP 242
Query: 286 NMVINMEWGNFKSE---RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKL 342
+VIN EWG F + R+ +D ++D +SL+PG+Q+YEKM+SGMYLGE+VR I++ L
Sbjct: 243 EVVINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRHIIVYL 302
Query: 343 AHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYI 402
LF +P +L+ R L T ++ + D +H L + L D L V I
Sbjct: 303 VEQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHLLYNTHYMLTDDLHVPVVEPIDNRI 362
Query: 403 TLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFRTC 462
+ C++V +R A LA AGI IL+++ R + +DG LY+ + KF
Sbjct: 363 VRYACEMVVKRAAYLAGAGIACILRRINRSE----------VTVGVDGSLYKFHPKFCER 412
Query: 463 LEATLADLLGEEAASSVVVKLANDGSGIGAALLAASHSQ 501
+ + L + + ++L+ DGSG GAA +AAS ++
Sbjct: 413 MTDMVDKL--KPKNTRFCLRLSEDGSGKGAAAIAASCTR 449
>2YHX-A nrPDB
Length = 457
Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats.
Identities = 85/464 (18%), Positives = 152/464 (32%), Gaps = 36/464 (7%)
Query: 47 AVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFY 106
+++E F P +L+ + + A + M+ +V +G + G F
Sbjct: 7 SLVEVHXXVFIVPPXILQAVVSILTT--RXDDXDSSAASIPMVPGWVLKQVSGAQAGSFL 64
Query: 107 ALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTS--MELFDFIAAELESFVK 164
A+ +GG + VI + L GR++ + A M T+ +L+ A
Sbjct: 65 AIVMGGGDLEVILISLAGRQESSIXASRSLAA----AMSTTAIPSDLWGNXAXS----NA 116
Query: 165 TEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAME 224
LGFTF + + G + FS+ +++ + A
Sbjct: 117 AFSSXEFSSXAGSVPLGFTFXEAGAKEXVIKGQITXQAXAFSLAXLX--KLISAMXNAXF 174
Query: 225 RQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAI--PKWTGLLP 282
G A + D+ G L Y D + +I G+G NAAY + I G
Sbjct: 175 PAGDXXXSVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAYWCDSTXIGDAADGGXXG 234
Query: 283 RSGNMVINMEWGNFKSE--RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 340
+G M I + +F+ LP+ Y L+ S + + K G+ +R +L+
Sbjct: 235 GAGXMXICCDQSSFRKAFPSLPQIXYLXTLNXXSPXAXK-TFXKNSXAKNXGQSLRDVLM 293
Query: 341 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 400
+ T + + DL+ G+A + +
Sbjct: 294 XFKXXGQX-HXXXAXSFXAANVENTSYPAKIQKLPHFDLRXXXDLFXGDQGIAXKTX-MK 351
Query: 401 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 460
+ L+A RL I I +K G IA G Y F
Sbjct: 352 XVVRRXLFLIAAYAFRLVVCXIXAICQKKGYS----------SGHIAAXGSX-RSYSGFS 400
Query: 461 TCLEATLADLLGEEA----ASSVVVKLANDGSGIGAALLAASHS 500
++ G + + + A DG G + ++ + S
Sbjct: 401 XNSATXNXNIYGWPQSAXXSKPIXITPAIDGXGAASXVIXSIAS 444
>1HKG-A nrPDB
Length = 457
Score = 135 bits (339), Expect = 6e-32, Method: Composition-based stats.
Identities = 83/469 (17%), Positives = 149/469 (31%), Gaps = 36/469 (7%)
Query: 42 RRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDE 101
+++E F P +L+ + + A + M+ +V G +
Sbjct: 2 ASXDXSLVEVHXXVFIVPPXILQAVVS--IATTRXDDXDSAAASIPMVPGWVLKQVXGSQ 59
Query: 102 HGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTS--MELFDFIAAEL 159
G F A+ +GG + VI + L G ++ + A M T+ +L+ A
Sbjct: 60 AGSFLAIVMGGGDLEVILIXLAGYQESSIXASRSLAA----SMXTTAIPSDLWGNXAXS- 114
Query: 160 ESFVKTEGEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAEL 219
LGFTF + + G + FS+ +++ +
Sbjct: 115 ---NAAFSSXEFSSXAGSVPLGFTFXEAGAKEXVIKGQITXQAXAFSLAXLX--KLISAM 169
Query: 220 SRAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAI--PKW 277
A G A + D+ G L Y D + +I G+G NAAY + I
Sbjct: 170 XNAXFPAGDXXXXVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAYWCDSTXIADAAD 229
Query: 278 TGLLPRSGNMVINMEWGNFKSE--RLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIV 335
G +G M + +F+ LP+ Y L+ S + +EK G+ +
Sbjct: 230 AGXXGGAGXMXVCCXQDSFRKAFPSLPQIXYXXTLNXXSPXAXK-TFEKNSXAKNXGQSL 288
Query: 336 RRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADT 395
R +L+ + + + + DL+ G+A
Sbjct: 289 RDVLMXYKXXGQX-HXXXAXDFXAANVENSSYPAKIQKLPHFDLRXXXDLFXGDQGIAXK 347
Query: 396 SLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEH 455
+ + + L+A RL I I +K G IA G
Sbjct: 348 TX-MKXVVRRXLFLIAAYAFRLVVCXIXAICQKKGYS----------SGHIAAXGSX-RD 395
Query: 456 YKKFRTCLEATLADLLGEEA----ASSVVVKLANDGSGIGAALLAASHS 500
Y F ++ G + + + A DG G ++ + S
Sbjct: 396 YSGFSXNSATXNXNIYGWPQSAXXSKPIXITPAIDGEGAAXXVIXSIAS 444
>1Q1R-A nrPDB
Length = 431
Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats.
Identities = 11/42 (26%), Positives = 14/42 (33%)
Query: 244 AGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSG 285
Y A V + TGT E + K T +L G
Sbjct: 193 VSAFYEHLHREAGVDIRTGTQVCGFEMSTDQQKVTAVLCEDG 234
>1E19-A nrPDB
Length = 314
Score = 28.8 bits (63), Expect = 6.0, Method: Composition-based stats.
Identities = 19/146 (13%), Positives = 45/146 (30%), Gaps = 20/146 (13%)
Query: 116 RVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFIAAELESFVKTEGEDFHLPEG 175
RV+ + LGG + Q+ + ++ IA + + + P+
Sbjct: 4 RVV-IALGGNALQQRGQKGSYEEMMDNVRKTARQ-----IAEIIARGYEVVITHGNGPQV 57
Query: 176 RQRELGF-----TFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQGLDM 230
L T+ P ++ W +G + L + ++G++
Sbjct: 58 GSLLLHMDAGQATYGIPAQPMDVAGAMSQGW---------IGYMIQQALKNELRKRGMEK 108
Query: 231 KVTALVNDTVGTLAGGRYVDNDVAAA 256
KV ++ T+ + +
Sbjct: 109 KVVTIITQTIVDKNDPAFQNPTKPVG 134
>6MU0-A nrPDB
Length = 160
Score = 28.8 bits (63), Expect = 6.1, Method: Composition-based stats.
Identities = 16/72 (22%), Positives = 27/72 (37%), Gaps = 4/72 (5%)
Query: 6 VVGTAVVVCAAAAAAVGVAVVVSRRRRSKREAEEERRRRAAAVIEEVEQRFSTPTALLRG 65
+ GT V VC AA GV + ++ A + + RF T + ++
Sbjct: 76 ICGTGVGVCMAANKVKGVLAALVVSEKTAALARQHDNANVLC----LSSRFVTDSENIKI 131
Query: 66 IADAMVEEMERG 77
+ D + E G
Sbjct: 132 VDDFLKANFEGG 143
>2WD5-A nrPDB
Length = 233
Score = 28.5 bits (62), Expect = 7.9, Method: Composition-based stats.
Identities = 31/154 (20%), Positives = 57/154 (37%), Gaps = 17/154 (11%)
Query: 302 PRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRF 361
P S Y +D P ++ Y+ ++ LG+ + I++ D + EQR
Sbjct: 52 PGSVYGRLIDL--CQPTQKKYQIAVT-KVLGKNMDAIIVDSEKTG---RDCIQYIKEQRG 105
Query: 362 ILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEARYITLHVCDLVAERGARLAAAG 421
T ++K KL+++ G RY H+ + A A G
Sbjct: 106 EPETFLPLD-----YLEVKPTDEKLRELKGAKLVIDVIRYEPPHI------KKALQYACG 154
Query: 422 IYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEH 455
+ + R + G ++ +ALDG L++
Sbjct: 155 NALVCDNVEDARRIAFGGHQRHKTVALDGTLFQK 188
>2BWY-A nrPDB
Length = 440
Score = 28.5 bits (62), Expect = 8.0, Method: Composition-based stats.
Identities = 27/116 (23%), Positives = 41/116 (35%), Gaps = 31/116 (26%)
Query: 258 ILGTGTNAAYVEHANA-IPKWTG--LLPRSGNMVINMEWGNFKSE------------RLP 302
I+G+G N + + G +L +G E+ + + +
Sbjct: 232 IVGSGENGCILHYTENECEMRDGDLVLIDAG-----CEYKGYAGDITRTFPVNGKFTQAQ 286
Query: 303 RSDYDNALD--FESLN---PGEQIYEKMISGMYLGEIVRRILLKLAHDASLFGDVV 353
R YD L+ SL PG I E GE+VR ++ L L GDV
Sbjct: 287 REIYDIVLESLETSLRLYRPGTSILE------VTGEVVRIMVSGLVKLGILKGDVD 336
>1Q5D-A nrPDB
Length = 419
Score = 28.1 bits (61), Expect = 9.7, Method: Composition-based stats.
Identities = 31/178 (17%), Positives = 59/178 (33%), Gaps = 16/178 (8%)
Query: 202 TKGFSINGTVGEDVVAELSRAMERQGLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGT 261
TK + T G ++ + R L+ V ++ + + I+
Sbjct: 195 TKTLVASVTEGLALLHGVLDERRRNPLENDVLTMLLQAEADGSRLSTKELVALVGAIIAA 254
Query: 262 GTNAAYVEHANAIPKWTGLLPRSGNMVINMEWGNFKSERLPRSDYDNALDFESLNPGEQI 321
GT+ A A+ L ++ E G ++ +DN L ++ Q
Sbjct: 255 GTDTTIYLIAFAVLNL--LRSPEALELVKAEPGLMRNALDEVLRFDNILRIGTVRFARQD 312
Query: 322 YEKMISGMYLGEIVRRILLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDL 379
E + + GE+V ++ P+ L + PD+ + DTS L
Sbjct: 313 LEYCGASIKKGEMVFLLI--------------PSALRDGTVFSRPDVFDVRRDTSASL 356
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.316 0.137 0.370
Lambda K H
0.267 0.0416 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,971,226
Number of Sequences: 36641
Number of extensions: 791088
Number of successful extensions: 2499
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2261
Number of HSP's gapped (non-prelim): 63
length of query: 506
length of database: 10,336,785
effective HSP length: 101
effective length of query: 405
effective length of database: 6,636,044
effective search space: 2687597820
effective search space used: 2687597820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)