BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8LPL7 (355 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6IJN-A nrPDB 725 0.0 6N9M-A nrPDB 102 2e-22 6N91-A nrPDB 100 1e-21 3IAR-A nrPDB 95 4e-20 2BGN-E nrPDB 93 2e-19 3KM8-A nrPDB 92 3e-19 2AMX-A nrPDB 86 3e-17 3PBM-A nrPDB 77 9e-15 6II7-A nrPDB 67 9e-12 3EWD-A nrPDB 67 2e-11 4GXW-A nrPDB 66 3e-11 3RYS-A nrPDB 61 8e-10 3LGD-A nrPDB 56 3e-08 3NQW-A nrPDB 29 2.4 >6IJN-A nrPDB Length = 376 Score = 725 bits (1871), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/355 (99%), Positives = 355/355 (100%) Query: 1 MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKL 60 MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKL Sbjct: 22 MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKL 81 Query: 61 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL 120 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL Sbjct: 82 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL 141 Query: 121 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD 180 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD Sbjct: 142 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD 201 Query: 181 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH 240 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH Sbjct: 202 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH 261 Query: 241 ACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFGVF 300 ACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCT+DFGVF Sbjct: 262 ACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTNDFGVF 321 Query: 301 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV 355 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV Sbjct: 322 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV 376 >6N9M-A nrPDB Length = 341 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 96/351 (27%), Positives = 151/351 (43%), Gaps = 40/351 (11%) Query: 6 SLPKIELHAHLNGSIRDSTLLELARV--LGEKGVIVFADVEHV-IQKNDRSLVEVFKLFD 62 +LP ++H HL+G+IR T+L+L R + + + HV + + LV D Sbjct: 5 TLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLD 64 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKR----SYMEAVIQ 118 K+ R+ E +ED A + Y+ELR +P + M+ + +EAVI Sbjct: 65 WGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPG---YMAMAHQLPIAGVVEAVID 121 Query: 119 GLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEM 178 G+R DG + RL+ + R + ++ + L Sbjct: 122 GVR----------------------DGCNTFGVEARLIGIMSRTFGEAACLQELDALLAH 159 Query: 179 RDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEI-QAMLDFKPHR 237 R+ + +DL+G+ L S FL A+D HIT+H GE P+ I QA+ + R Sbjct: 160 RE-NITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER 218 Query: 238 IGHACFFKDEDWTKLKSF----RIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILC 293 IGH K + L F RI +E CLTSNI T +++S+ H L Sbjct: 219 IGHGV--KAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLN 276 Query: 294 TDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLR 344 TDD V + +EY +A + GLS+ + ++ F D K+ LR Sbjct: 277 TDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALR 327 >6N91-A nrPDB Length = 340 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 91/341 (26%), Positives = 145/341 (42%), Gaps = 34/341 (9%) Query: 6 SLPKIELHAHLNGSIRDSTLLELARVLGEK-GVIVFADVEHVIQ--KNDRSLVEVFKLFD 62 SLP +LH HL+G+IR T+LEL + G K + +Q + + SLV D Sbjct: 5 SLPLTDLHRHLDGNIRTQTILELGQKFGVKLPANTLQTLTPYVQIVEAEPSLVAFLSKLD 64 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTP-KRSDSIGMSKRSYMEAVIQGLR 121 + D R+ E VED + Y ELR +P + + +EAV+ G+R Sbjct: 65 WGVAVLGDLDACRRVAYENVEDALNARIDYAELRFSPYYMAMKHSLPVTGVVEAVVDGVR 124 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 + G+ I L+ + R T++ + + L ++ Sbjct: 125 A----------------------GVRDFGIQANLIGIMSRTFGTDACQQELDAILSQKN- 161 Query: 182 GVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEI-QAMLDFKPHRIGH 240 +V +DL+G+ L F+ + +D LH+T+H GE P+ + QA+ D RIGH Sbjct: 162 HIVAVDLAGDELGQPGDRFIQHFKQVRDAGLHVTVHAGEAAGPESMWQAIRDLGATRIGH 221 Query: 241 A--CFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILC--TDD 296 + L RI +E CLTSN+ T ++ S+ H +H ++ C TDD Sbjct: 222 GVKAIHDPKLMDYLAQHRIGIESCLTSNLQTSTVDSLATHPLKRFL--EHGILACINTDD 279 Query: 297 FGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAED 337 V L EY +A GLS+ + ++ F D Sbjct: 280 PAVEGIELPYEYEVAAPQAGLSQEQIRQAQLNGLELAFLSD 320 >3IAR-A nrPDB Length = 367 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 99/357 (27%), Positives = 168/357 (47%), Gaps = 31/357 (8%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVE----HVIQKNDR-SLVEVFKLFD 62 PK+ELH HL+GSI+ T+L R +G+ + A+ +VI + +L + FD Sbjct: 7 PKVELHVHLDGSIKPETILYYGR---RRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFD 63 Query: 63 L-IHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLR 121 + + + + RI E VE A E VVY+E+R +P + S +E + + Sbjct: 64 YYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPH------LLANSKVEPIPWN-Q 116 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 + ++ D V A Q L G K R +L R + S + V+L + + Sbjct: 117 AEGDLTPDEVVALVGQGLQEGERDFGVK---ARSILCCMRHQPNWSP-KVVELCKKYQQQ 172 Query: 182 GVVGIDLSGNPLVGEWSTFLP----ALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPH 236 VV IDL+G+ + S+ LP A Q A + +H T+H GEV + + ++ +D K Sbjct: 173 TVVAIDLAGDETI-PGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTE 231 Query: 237 RIGHACFFKDED---WTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILC 293 R+GH + ED + +L+ + EIC S+ +T + H L N + L Sbjct: 232 RLGHG-YHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLN 290 Query: 294 TDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATF-AEDEVKQQLRFIFDS 349 TDD +F ++L +Y + R +G ++ E L A ++F EDE ++ L ++ + Sbjct: 291 TDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKA 347 >2BGN-E nrPDB Length = 363 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 95/357 (26%), Positives = 166/357 (46%), Gaps = 31/357 (8%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEH-----VIQKNDRSLVEVFKLFD 62 PK+ELH HL+G+I+ T+L + +G+ + AD + +L + FD Sbjct: 10 PKVELHVHLDGAIKPETILYYGK---RRGIALPADTPEELLNIIGMDKPLTLPDFLAKFD 66 Query: 63 L-IHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLR 121 + + + RI E VE A + VVY+E+R +P + S +E + + Sbjct: 67 YYMPAIAGCRDAIKRIAYEFVEMKAKDGVVYVEVRYSPH------LLANSKVEPIPWN-Q 119 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 + ++ D V + +Q L G K VR +L R + + S+ E V+L + R+ Sbjct: 120 AEGDLTPDEVVSLVNQGLQEGERDFGVK---VRSILCCMRHQPSWSS-EVVELCKKYREQ 175 Query: 182 GVVGIDLSGNPLVGEWSTFLP----ALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPH 236 VV IDL+G+ + E S+ P A A + +H T+H GEV + ++ +D K Sbjct: 176 TVVAIDLAGDETI-EGSSLFPGHVQAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTE 234 Query: 237 RIGHACFFKDED---WTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILC 293 R+GH + ED + +L+ + EIC S+ +T + H N + L Sbjct: 235 RLGHG-YHTLEDTTLYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRFKNDQVNYSLN 293 Query: 294 TDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATF-AEDEVKQQLRFIFDS 349 TDD +F ++L +Y + + +G ++ E L A ++F EDE K+ L ++ + Sbjct: 294 TDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKA 350 >3KM8-A nrPDB Length = 352 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 97/342 (28%), Positives = 162/342 (47%), Gaps = 32/342 (9%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFAD-VEHV--IQKNDR--SLVEVFKLFD 62 PK+ELH HL+G+I+ T+L + ++G+ + AD VE + I D+ SL FD Sbjct: 10 PKVELHVHLDGAIKPETILYFGK---KRGIALPADTVEELRNIIGMDKPLSLPGFLAKFD 66 Query: 63 LIHKLTTD-HKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLR 121 + + + RI E VE A E VVY+E+R +P + SK M Sbjct: 67 YYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHL---LANSKVDPMPW------ 117 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKK--IYVRLLLSIDRRETTESAMETVKLALEMR 179 + +E D VT D L N G G + I VR +L R + + S +E ++L + Sbjct: 118 NQTEGD---VTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWS-LEVLELCKKYN 173 Query: 180 DVGVVGIDLSGNPLVGEWSTFLP----ALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FK 234 VV +DL+G+ + E S+ P A + A N +H T+H G+V +P+ ++ +D K Sbjct: 174 QKTVVAMDLAGDETI-EGSSLFPGHVEAYEGAVKNGIHRTVHAGQVGSPEVVREAVDILK 232 Query: 235 PHRIGHACFFKDED--WTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLIL 292 R+GH +++ + +L + E+C S+ +T + H N K L Sbjct: 233 TERVGHGEHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSL 292 Query: 293 CTDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATF 334 TDD +F ++L +Y + + +G ++ E L A ++F Sbjct: 293 NTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSF 334 >2AMX-A nrPDB Length = 376 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 83/352 (23%), Positives = 157/352 (44%), Gaps = 32/352 (9%) Query: 5 QSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADV--EHVIQKNDRSLVEVFKLFD 62 + +PK+ELH HL+ + L+ AR + + ++ ++ K +SL E + Sbjct: 47 RRIPKVELHCHLDLTFSAEFFLKWARKYNLQPNMSDDEILDHYLFTKEGKSLAEFIRKAI 106 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKR-SDSIGMSKRSYMEAVIQGLR 121 + L D+ + + + V + E VV +E R +P S S G+ +A I+G++ Sbjct: 107 SVSDLYRDYDFIEDLAKWAVIEKYKEGVVLMEFRYSPTFVSSSYGLDVELIHKAFIKGIK 166 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 + +E+ L+N KI+V L+ D S + A++ + Sbjct: 167 NATEL------------LNN--------KIHVALICISDTGHAAASIKHSGDFAIKHKH- 205 Query: 182 GVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGE---VPNPKEIQAMLD-FKPHR 237 VG D G + + +D+ LH+T+H GE +PN + ++ R Sbjct: 206 DFVGFDHGGREI--DLKDHKDVYHSVRDHGLHLTVHAGEDATLPNLNTLYTAINILNVER 263 Query: 238 IGHACFFK--DEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 IGH DE +K I +E+C SN++ ++ S+D H LY+A + + +D Sbjct: 264 IGHGIRVSESDELIELVKKKDILLEVCPISNLLLNNVKSMDTHPIRKLYDAGVKVSVNSD 323 Query: 296 DFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIF 347 D G+F +++++ Y L + E + A + +F D+VK +L+ ++ Sbjct: 324 DPGMFLSNINDNYEKLYIHLNFTLEEFMIMNNWAFEKSFVSDDVKSELKALY 375 >3PBM-A nrPDB Length = 326 Score = 77.4 bits (189), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 87/343 (25%), Positives = 144/343 (41%), Gaps = 35/343 (10%) Query: 2 EWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKND-RSLVEVFKL 60 EW+ +LPK ELH HL G++ L LA + + + DVE + + +L E L Sbjct: 5 EWLNALPKAELHLHLEGTLEPELLFALAE--RNRIALPWNDVETLRKAYAFNNLQEFLDL 62 Query: 61 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL 120 + + + +T ++ +NVV++E P+ G+ E V+ G+ Sbjct: 63 YYAGADVLRTEQDFYDLTWAYLQKCKAQNVVHVEPFFDPQTHTDRGIP----FEVVLAGI 118 Query: 121 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD 180 R+ D +KL G L+LS R + E A +T+ AL RD Sbjct: 119 RA---------ALRDGEKLLGIRHG---------LILSFLRHLSEEQAQKTLDQALPFRD 160 Query: 181 VGV-VGIDLS--GNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPH 236 + VG+D S G+P S F A+ H GE P+ I LD K Sbjct: 161 AFIAVGLDSSEVGHPP----SKFQRVFDRARSEGFLTVAHAGEEGPPEYIWEALDLLKVE 216 Query: 237 RIGHAC-FFKDEDWT-KLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCT 294 RI H F+DE +L +IP+ +C SN + H D+ + + + Sbjct: 217 RIDHGVRAFEDERLMRRLIDEQIPLTVCPLSNTKLCVFDDMSQHTILDMLERGVKVTVNS 276 Query: 295 DDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAED 337 DD F ++ + +SLG+++ + LA+ ++DA ++ Sbjct: 277 DDPAYFGGYVTENFHALQQSLGMTEEQARRLAQNSLDARLVKE 319 >6II7-A nrPDB Length = 367 Score = 67.4 bits (163), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 79/356 (22%), Positives = 151/356 (42%), Gaps = 45/356 (12%) Query: 3 WIQSLPKIELHAHLNGSIRDSTLLELARV------LGEKGVIVFADVEHVIQKNDRSLVE 56 W + LPK ELH HL+ L + R + ++ +I + ++ K +SL E Sbjct: 37 W-KRLPKCELHCHLDVCFSVDFFLNVIRKYNIQPNMSDEEIIDY----YLFSKPGKSLDE 91 Query: 57 VFKLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPK-RSDSIGMSKRSYMEA 115 + + + D+ V + + V + E VV +E R +P S + K EA Sbjct: 92 FVEKALRLTDIYIDYTVVEDLAKHAVFNKYKEGVVLMEFRYSPSFMSFKHNLDKDLIHEA 151 Query: 116 VIQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLA 175 +++GL N + KI V LL + D + E E + Sbjct: 152 IVKGL--------------------NEAVALLEYKIQVGLLCTGDGGLSHERMKEAAEFC 191 Query: 176 LEMRDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGE---VPNPKEIQAMLD 232 ++ + VG D +G+ + + F ++ + I++H GE +PN + ++ Sbjct: 192 IKHKK-DFVGYDHAGHEV--DLKPFKDIFDNIREEGISISVHAGEDVSIPNLNSLYTAIN 248 Query: 233 F-KPHRIGHACFFKDE----DWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAK 287 RIGH + D K K I +E+C SN++ ++ S+D H LY+A Sbjct: 249 LLHVKRIGHGIRVSESQELIDLVKEKD--ILLEVCPISNVLLNNVKSMDTHPIRMLYDAG 306 Query: 288 HPLILCTDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQL 343 + + +DD G+F T++++ Y L + ++ + A+ +F + ++K ++ Sbjct: 307 VKVSVNSDDPGMFLTNITDNYEELYTHLNFTLADFMKMNLWAVQKSFVDPDIKNKI 362 >3EWD-A nrPDB Length = 370 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 75/358 (20%), Positives = 157/358 (43%), Gaps = 42/358 (11%) Query: 3 WIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADV--EHVIQKNDRSLVE---- 56 W + +PK ELH HL+ + R + + +V ++ K +SL E Sbjct: 33 W-KRIPKCELHCHLDLCFSADFFVSCIRKYNLQPNLSDEEVLDYYLFAKGGKSLGEFVEK 91 Query: 57 VFKLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKR-SDSIGMSKRSYMEA 115 K+ D+ H D++ + + + V + E VV +E R +P + + +A Sbjct: 92 AIKVADIFH----DYEVIEDLAKHAVFNKYKEGVVLMEFRYSPTFVAFKYNLDIELIHQA 147 Query: 116 VIQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLA 175 +++G++ V E+ +D K+H A L+ I + + Sbjct: 148 IVKGIKEVVEL-LD-------HKIHVA-------------LMCIGTGHEAANIKASADFC 186 Query: 176 LEMRDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGE---VPNPKEIQAMLD 232 L+ + VG D G+ + + + Y +++ + +++H GE +PN + + + Sbjct: 187 LKHK-ADFVGFDHGGHEV--DLKEYKEIFDYVRESGVPLSVHAGEDVTLPNLNTLYSAIQ 243 Query: 233 -FKPHRIGHACFFKD--EDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHP 289 K RIGH + E +K I +E+C SN++ K+ S+D H LY+A Sbjct: 244 VLKVERIGHGIRVAESQELIDMVKEKNILLEVCPISNVLLKNAKSMDTHPIRQLYDAGVK 303 Query: 290 LILCTDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIF 347 + + +DD G+F T+++++Y L + + + A++ +F + +K +++ ++ Sbjct: 304 VSVNSDDPGMFLTNINDDYEELYTHLNFTLEDFMKMNEWALEKSFMDSNIKDKIKNLY 361 >4GXW-A nrPDB Length = 380 Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 83/358 (23%), Positives = 139/358 (38%), Gaps = 50/358 (13%) Query: 4 IQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKLFDL 63 +LPK+ELH HL G++R T + LA+ G I A+++ + ++ + + L L Sbjct: 26 FHALPKVELHCHLLGAVRHDTFVALAQRSGAP--IERAEIDAFYARGEKPVGVLHVLRAL 83 Query: 64 IHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSI-GMSKRSYMEAVIQGLRS 122 L T + RI E +ED A NV + E P + + G+ A++ G+R Sbjct: 84 DRYLLTRPDDLRRIAYEYLEDAAAHNVRHAEFFWNPTGTVRVSGIPYADAQAAIVTGMRD 143 Query: 123 VSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMR--D 180 + DF GIG RL+ SIDR + + A+ V R + Sbjct: 144 AAR---DF--------------GIG-----ARLIPSIDREQDPDEAVAIVDWMKANRADE 181 Query: 181 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNP-KEIQAMLD-FKPHRI 238 V +GID N E F A + A+ T H GE P + ++ +D R+ Sbjct: 182 VAGIGIDYRENDRPPE--LFWKAYRDARAAGFRTTAHAGEFGMPWRNVETAVDLLHVDRV 239 Query: 239 GHACFFKD--EDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILC--- 293 H D E + I + T++ +++ D + +HP+ Sbjct: 240 DHGYTIVDNPELCARYAERGIVFTVVPTNSYYLRTLPP-------DQWAERHPMRKMPGL 292 Query: 294 -------TDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLR 344 TDD + + S + L G + ++ ID + +D+ K R Sbjct: 293 GLKIHPNTDDPTLHKVNPSEAWELMFSHFGFTIADLKQFMLNGIDGAWVDDDTKAAWR 350 >3RYS-A nrPDB Length = 343 Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 77/343 (22%), Positives = 141/343 (41%), Gaps = 35/343 (10%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVF-KLFDLIHK 66 P ELH H+ G+++ + LA G + + + D+E + +K + + ++ F L+ Sbjct: 14 PVAELHLHIEGTLQPELIFALAERNGIE--LPYEDIEELREKYEFTDLQSFLDLYYANMA 71 Query: 67 LTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLRSVSEV 126 + + T +TR +E A V + E+ P+ S G++ + + V L + E Sbjct: 72 VLQTEQDFTDMTRAYLERAAAGGVRHAEIMMDPQAHTSRGVALETCVNGVANALATSEE- 130 Query: 127 DIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMR-DVGVVG 185 DF + L+ + R + +SA+E + L M + +G Sbjct: 131 --DF-------------------GVSTLLIAAFLRDMSEDSALEVLDQLLAMHAPIAGIG 169 Query: 186 IDLS--GNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPHRIGHA- 241 +D + GNP S F Q A + L H GE I LD RI H Sbjct: 170 LDSAEVGNP----PSKFERLYQRAAEAGLRRIAHAGEEGPASYITEALDVLHVERIDHGI 225 Query: 242 -CFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFGVF 300 C + +L + ++P+ +C SN+ +++ + H ++ + + +DD F Sbjct: 226 RCMEDTDVVQRLVAEQVPLTVCPLSNVRLRAVDKLADHPLPEMLAIGLNVCVNSDDPAYF 285 Query: 301 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQL 343 + + + V+ L S E LA +I ++FA D K L Sbjct: 286 GGYVDDNFEQLVKVLEFSVPEQATLAANSIRSSFASDARKAVL 328 >3LGD-A nrPDB Length = 508 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 83/320 (25%), Positives = 130/320 (40%), Gaps = 47/320 (14%) Query: 58 FKLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVI 117 F + LIH V R +E ED NV+Y+E+R + +S + E Sbjct: 186 FTISGLIHYAPVFRDYVFRSMQEFYED----NVLYMEIRA--RLLPVYELSGEHHDEE-- 237 Query: 118 QGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALE 177 +++ EV FV + IG K IY S R + E++++A+ Sbjct: 238 WSVKTYQEVAQKFVETHP--------EFIGIKIIY-----SDHRSKDVAVIAESIRMAMG 284 Query: 178 MR---DVGVVGIDLSGNPLVGE-WSTFLPALQY-AKDN-DLHITLHCGEVPNP-----KE 226 +R V G DL G+ G + AL AKD L H GE + Sbjct: 285 LRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRN 344 Query: 227 IQAMLDFKPHRIGHACFFKDEDWTKLKSFR--IPVEICLTSNIVTKSISSIDIHHFADLY 284 I L RIGH + S++ IP+E+C SN V K +S + H A L Sbjct: 345 ILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLM 404 Query: 285 NAKHPLILCTDDFGVF-STSLSNEYALAVRSLGLSKSETFALARAAIDA----------- 332 HP+++ +DD +F + LS ++ +G K++ L + A+++ Sbjct: 405 ATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEK 464 Query: 333 -TFAEDEVKQQLRFIFDSAS 351 TF E K+ +FI D A+ Sbjct: 465 NTFMEIWKKRWDKFIADVAT 484 >3NQW-A nrPDB Length = 179 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 9/74 (12%) Query: 15 HLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKLFDLIHKLTTDHKTV 74 ++N I ST+L + + ++GV++ A + V++ D S +V KLF V Sbjct: 33 YVNHVINVSTILSVEACITDEGVLMAALLHDVVEDTDASFEDVEKLF---------GPDV 83 Query: 75 TRITREVVEDFALE 88 + REV +D +LE Sbjct: 84 CGLVREVTDDKSLE 97 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6IJN-A nrPDB 429 e-121 2BGN-E nrPDB 346 6e-96 3IAR-A nrPDB 346 1e-95 2AMX-A nrPDB 332 1e-91 3KM8-A nrPDB 328 2e-90 3EWD-A nrPDB 327 4e-90 6II7-A nrPDB 327 6e-90 6N9M-A nrPDB 314 3e-86 6N91-A nrPDB 313 8e-86 3PBM-A nrPDB 297 6e-81 4GXW-A nrPDB 291 3e-79 3RYS-A nrPDB 289 9e-79 3LGD-A nrPDB 231 4e-61 Sequences not found previously or not previously below threshold: 2A3L-A nrPDB 49 4e-06 2BB0-A nrPDB 44 8e-05 2OOF-A nrPDB 40 0.001 2I9U-A nrPDB 37 0.011 2PAJ-A nrPDB 33 0.20 2Z9W-A nrPDB 33 0.22 3ROR-A nrPDB 33 0.27 2OOD-A nrPDB 31 0.59 3E0L-A nrPDB 31 0.60 4DYK-A nrPDB 31 0.65 4V1Y-A nrPDB 31 0.74 2PUZ-A nrPDB 31 0.76 4CJ9-A nrPDB 31 1.0 4TO8-A nrPDB 30 1.9 3Q94-A nrPDB 29 2.2 2IDA-A nrPDB 29 2.4 3I6S-A nrPDB 29 2.7 2NX9-A nrPDB 29 2.9 4R7W-A nrPDB 29 3.3 1N0W-A nrPDB 29 4.3 5H1C-A nrPDB 29 4.4 1H54-A nrPDB 28 5.2 1H4S-A nrPDB 28 6.9 3V7P-A nrPDB 28 7.4 >6IJN-A nrPDB Length = 376 Score = 429 bits (1102), Expect = e-121, Method: Composition-based stats. Identities = 354/355 (99%), Positives = 355/355 (100%) Query: 1 MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKL 60 MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKL Sbjct: 22 MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKL 81 Query: 61 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL 120 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL Sbjct: 82 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL 141 Query: 121 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD 180 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD Sbjct: 142 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD 201 Query: 181 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH 240 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH Sbjct: 202 VGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH 261 Query: 241 ACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFGVF 300 ACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCT+DFGVF Sbjct: 262 ACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTNDFGVF 321 Query: 301 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV 355 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV Sbjct: 322 STSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV 376 >2BGN-E nrPDB Length = 363 Score = 346 bits (888), Expect = 6e-96, Method: Composition-based stats. Identities = 92/355 (25%), Positives = 164/355 (46%), Gaps = 27/355 (7%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEH-----VIQKNDRSLVEVFKLFD 62 PK+ELH HL+G+I+ T+L + +G+ + AD + +L + FD Sbjct: 10 PKVELHVHLDGAIKPETILYYGKR---RGIALPADTPEELLNIIGMDKPLTLPDFLAKFD 66 Query: 63 L-IHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLR 121 + + + RI E VE A + VVY+E+R +P + S +E + + Sbjct: 67 YYMPAIAGCRDAIKRIAYEFVEMKAKDGVVYVEVRYSPH------LLANSKVEPIPWN-Q 119 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 + ++ D V + +Q L G K VR +L R + + S+ E V+L + R+ Sbjct: 120 AEGDLTPDEVVSLVNQGLQEGERDFGVK---VRSILCCMRHQPSWSS-EVVELCKKYREQ 175 Query: 182 GVVGIDLSGNPLVGEWSTF---LPALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPHR 237 VV IDL+G+ + S F + A A + +H T+H GEV + ++ +D K R Sbjct: 176 TVVAIDLAGDETIEGSSLFPGHVQAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTER 235 Query: 238 IGHACFFKDE--DWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 +GH ++ + +L+ + EIC S+ +T + H N + L TD Sbjct: 236 LGHGYHTLEDTTLYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRFKNDQVNYSLNTD 295 Query: 296 DFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATF-AEDEVKQQLRFIFDS 349 D +F ++L +Y + + +G ++ E L A ++F EDE K+ L ++ + Sbjct: 296 DPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKA 350 >3IAR-A nrPDB Length = 367 Score = 346 bits (886), Expect = 1e-95, Method: Composition-based stats. Identities = 94/353 (26%), Positives = 160/353 (45%), Gaps = 23/353 (6%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLG--EKGVIVFADVEHVIQKNDRSLVEVFKLFDL-I 64 PK+ELH HL+GSI+ T+L R G + + +L + FD + Sbjct: 7 PKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYM 66 Query: 65 HKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLRSVS 124 + + + RI E VE A E VVY+E+R +P + S +E + ++ Sbjct: 67 PAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPH------LLANSKVEPIPWN-QAEG 119 Query: 125 EVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDVGVV 184 ++ D V A Q L G K R +L R + S + V+L + + VV Sbjct: 120 DLTPDEVVALVGQGLQEGERDFGVK---ARSILCCMRHQPNWSP-KVVELCKKYQQQTVV 175 Query: 185 GIDLSGNPLVGEWSTFLP----ALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPHRIG 239 IDL+G+ + S+ LP A Q A + +H T+H GEV + + ++ +D K R+G Sbjct: 176 AIDLAGDETI-PGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLG 234 Query: 240 HACFFKDE--DWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDF 297 H ++ + +L+ + EIC S+ +T + H L N + L TDD Sbjct: 235 HGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDP 294 Query: 298 GVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATF-AEDEVKQQLRFIFDS 349 +F ++L +Y + R +G ++ E L A ++F EDE ++ L ++ + Sbjct: 295 LIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKA 347 >2AMX-A nrPDB Length = 376 Score = 332 bits (852), Expect = 1e-91, Method: Composition-based stats. Identities = 82/355 (23%), Positives = 156/355 (43%), Gaps = 32/355 (9%) Query: 2 EWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADV--EHVIQKNDRSLVEVFK 59 E + +PK+ELH HL+ + L+ AR + + ++ ++ K +SL E + Sbjct: 44 EIWRRIPKVELHCHLDLTFSAEFFLKWARKYNLQPNMSDDEILDHYLFTKEGKSLAEFIR 103 Query: 60 LFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKR-SDSIGMSKRSYMEAVIQ 118 + L D+ + + + V + E VV +E R +P S S G+ +A I+ Sbjct: 104 KAISVSDLYRDYDFIEDLAKWAVIEKYKEGVVLMEFRYSPTFVSSSYGLDVELIHKAFIK 163 Query: 119 GLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEM 178 G+++ +E+ + KI+V L+ D S + A++ Sbjct: 164 GIKNATELLNN--------------------KIHVALICISDTGHAAASIKHSGDFAIKH 203 Query: 179 RDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGE---VPNPKEIQAMLD-FK 234 + VG D G + + +D+ LH+T+H GE +PN + ++ Sbjct: 204 KH-DFVGFDHGGREI--DLKDHKDVYHSVRDHGLHLTVHAGEDATLPNLNTLYTAINILN 260 Query: 235 PHRIGHACFFK--DEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLIL 292 RIGH DE +K I +E+C SN++ ++ S+D H LY+A + + Sbjct: 261 VERIGHGIRVSESDELIELVKKKDILLEVCPISNLLLNNVKSMDTHPIRKLYDAGVKVSV 320 Query: 293 CTDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIF 347 +DD G+F +++++ Y L + E + A + +F D+VK +L+ ++ Sbjct: 321 NSDDPGMFLSNINDNYEKLYIHLNFTLEEFMIMNNWAFEKSFVSDDVKSELKALY 375 >3KM8-A nrPDB Length = 352 Score = 328 bits (841), Expect = 2e-90, Method: Composition-based stats. Identities = 87/339 (25%), Positives = 151/339 (44%), Gaps = 24/339 (7%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVI----QKNDRSLVEVFKLFDL 63 PK+ELH HL+G+I+ T+L + G + VE + SL FD Sbjct: 10 PKVELHVHLDGAIKPETILYFGKKRGI--ALPADTVEELRNIIGMDKPLSLPGFLAKFDY 67 Query: 64 IHKLT-TDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLRS 122 + + + RI E VE A E VVY+E+R +P + S ++ + ++ Sbjct: 68 YMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPH------LLANSKVDPMPWN-QT 120 Query: 123 VSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDVG 182 +V D V +Q L G I VR +L R + + S +E ++L + Sbjct: 121 EGDVTPDDVVDLVNQGLQEGEQAFG---IKVRSILCCMRHQPSWS-LEVLELCKKYNQKT 176 Query: 183 VVGIDLSGNPLVGEWSTF---LPALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPHRI 238 VV +DL+G+ + S F + A + A N +H T+H G+V +P+ ++ +D K R+ Sbjct: 177 VVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGQVGSPEVVREAVDILKTERV 236 Query: 239 GHACFFKDE--DWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDD 296 GH ++ + +L + E+C S+ +T + H N K L TDD Sbjct: 237 GHGEHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDD 296 Query: 297 FGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFA 335 +F ++L +Y + + +G ++ E L A ++F Sbjct: 297 PLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFL 335 >3EWD-A nrPDB Length = 370 Score = 327 bits (838), Expect = 4e-90, Method: Composition-based stats. Identities = 70/352 (19%), Positives = 152/352 (43%), Gaps = 33/352 (9%) Query: 5 QSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADV--EHVIQKNDRSLVEVFKLFD 62 + +PK ELH HL+ + R + + +V ++ K +SL E + Sbjct: 34 KRIPKCELHCHLDLCFSADFFVSCIRKYNLQPNLSDEEVLDYYLFAKGGKSLGEFVEKAI 93 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKR-SDSIGMSKRSYMEAVIQGLR 121 + + D++ + + + V + E VV +E R +P + + +A+++G++ Sbjct: 94 KVADIFHDYEVIEDLAKHAVFNKYKEGVVLMEFRYSPTFVAFKYNLDIELIHQAIVKGIK 153 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 V E+ KI+V L + I + + L+ + Sbjct: 154 EVVEL--------------------LDHKIHVAL-MCIGTGHEAANIKASADFCLKHK-A 191 Query: 182 GVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGE---VPNPKEIQAMLD-FKPHR 237 VG D G+ + + + Y +++ + +++H GE +PN + + + K R Sbjct: 192 DFVGFDHGGHEV--DLKEYKEIFDYVRESGVPLSVHAGEDVTLPNLNTLYSAIQVLKVER 249 Query: 238 IGHACFFKD--EDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 IGH + E +K I +E+C SN++ K+ S+D H LY+A + + +D Sbjct: 250 IGHGIRVAESQELIDMVKEKNILLEVCPISNVLLKNAKSMDTHPIRQLYDAGVKVSVNSD 309 Query: 296 DFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRFIF 347 D G+F T+++++Y L + + + A++ +F + +K +++ ++ Sbjct: 310 DPGMFLTNINDDYEELYTHLNFTLEDFMKMNEWALEKSFMDSNIKDKIKNLY 361 >6II7-A nrPDB Length = 367 Score = 327 bits (837), Expect = 6e-90, Method: Composition-based stats. Identities = 76/348 (21%), Positives = 148/348 (42%), Gaps = 32/348 (9%) Query: 5 QSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADV--EHVIQKNDRSLVEVFKLFD 62 + LPK ELH HL+ L + R + + ++ ++ K +SL E + Sbjct: 38 KRLPKCELHCHLDVCFSVDFFLNVIRKYNIQPNMSDEEIIDYYLFSKPGKSLDEFVEKAL 97 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPK-RSDSIGMSKRSYMEAVIQGLR 121 + + D+ V + + V + E VV +E R +P S + K EA+++GL Sbjct: 98 RLTDIYIDYTVVEDLAKHAVFNKYKEGVVLMEFRYSPSFMSFKHNLDKDLIHEAIVKGL- 156 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 N + KI V LL + D + E E + ++ + Sbjct: 157 -------------------NEAVALLEYKIQVGLLCTGDGGLSHERMKEAAEFCIKHKK- 196 Query: 182 GVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGE---VPNPKEIQAMLDF-KPHR 237 VG D +G+ + + F ++ + I++H GE +PN + ++ R Sbjct: 197 DFVGYDHAGHEV--DLKPFKDIFDNIREEGISISVHAGEDVSIPNLNSLYTAINLLHVKR 254 Query: 238 IGHACFFKD--EDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 IGH + E +K I +E+C SN++ ++ S+D H LY+A + + +D Sbjct: 255 IGHGIRVSESQELIDLVKEKDILLEVCPISNVLLNNVKSMDTHPIRMLYDAGVKVSVNSD 314 Query: 296 DFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQL 343 D G+F T++++ Y L + ++ + A+ +F + ++K ++ Sbjct: 315 DPGMFLTNITDNYEELYTHLNFTLADFMKMNLWAVQKSFVDPDIKNKI 362 >6N9M-A nrPDB Length = 341 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 91/346 (26%), Positives = 146/346 (42%), Gaps = 30/346 (8%) Query: 6 SLPKIELHAHLNGSIRDSTLLELARVLG--EKGVIVFADVEHV-IQKNDRSLVEVFKLFD 62 +LP ++H HL+G+IR T+L+L R + + HV + + LV D Sbjct: 5 TLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLD 64 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTP-KRSDSIGMSKRSYMEAVIQGLR 121 K+ R+ E +ED A + Y+ELR +P + + + +EAVI G+R Sbjct: 65 WGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVR 124 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 DG + RL+ + R + ++ + L R+ Sbjct: 125 ----------------------DGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHRE- 161 Query: 182 GVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAML-DFKPHRIGH 240 + +DL+G+ L S FL A+D HIT+H GE P+ I + + RIGH Sbjct: 162 NITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGH 221 Query: 241 ACFFKDE--DWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFG 298 ++ L RI +E CLTSNI T +++S+ H L TDD Sbjct: 222 GVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPA 281 Query: 299 VFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLR 344 V + +EY +A + GLS+ + ++ F D K+ LR Sbjct: 282 VQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALR 327 >6N91-A nrPDB Length = 340 Score = 313 bits (801), Expect = 8e-86, Method: Composition-based stats. Identities = 87/341 (25%), Positives = 139/341 (40%), Gaps = 30/341 (8%) Query: 6 SLPKIELHAHLNGSIRDSTLLELARVLGEK-GVIVFADVEHVIQ--KNDRSLVEVFKLFD 62 SLP +LH HL+G+IR T+LEL + G K + +Q + + SLV D Sbjct: 5 SLPLTDLHRHLDGNIRTQTILELGQKFGVKLPANTLQTLTPYVQIVEAEPSLVAFLSKLD 64 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPK-RSDSIGMSKRSYMEAVIQGLR 121 + D R+ E VED + Y ELR +P + + +EAV+ G+R Sbjct: 65 WGVAVLGDLDACRRVAYENVEDALNARIDYAELRFSPYYMAMKHSLPVTGVVEAVVDGVR 124 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDV 181 + G+ I L+ + R T++ + + L ++ Sbjct: 125 A----------------------GVRDFGIQANLIGIMSRTFGTDACQQELDAILSQKN- 161 Query: 182 GVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAML-DFKPHRIGH 240 +V +DL+G+ L F+ + +D LH+T+H GE P+ + + D RIGH Sbjct: 162 HIVAVDLAGDELGQPGDRFIQHFKQVRDAGLHVTVHAGEAAGPESMWQAIRDLGATRIGH 221 Query: 241 AC--FFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFG 298 + L RI +E CLTSN+ T ++ S+ H + TDD Sbjct: 222 GVKAIHDPKLMDYLAQHRIGIESCLTSNLQTSTVDSLATHPLKRFLEHGILACINTDDPA 281 Query: 299 VFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEV 339 V L EY +A GLS+ + ++ F D Sbjct: 282 VEGIELPYEYEVAAPQAGLSQEQIRQAQLNGLELAFLSDSE 322 >3PBM-A nrPDB Length = 326 Score = 297 bits (759), Expect = 6e-81, Method: Composition-based stats. Identities = 82/341 (24%), Positives = 139/341 (40%), Gaps = 31/341 (9%) Query: 2 EWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKND-RSLVEVFKL 60 EW+ +LPK ELH HL G++ L LA + + + DVE + + +L E L Sbjct: 5 EWLNALPKAELHLHLEGTLEPELLFALAERN--RIALPWNDVETLRKAYAFNNLQEFLDL 62 Query: 61 FDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGL 120 + + + +T ++ +NVV++E P+ G+ E V+ G+ Sbjct: 63 YYAGADVLRTEQDFYDLTWAYLQKCKAQNVVHVEPFFDPQTHTDRGIP----FEVVLAGI 118 Query: 121 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRD 180 R+ D +KL G L+LS R + E A +T+ AL RD Sbjct: 119 RAA---------LRDGEKLLGIRHG---------LILSFLRHLSEEQAQKTLDQALPFRD 160 Query: 181 VGV-VGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDF-KPHRI 238 + VG+D S + S F A+ H GE P+ I LD K RI Sbjct: 161 AFIAVGLDSS--EVGHPPSKFQRVFDRARSEGFLTVAHAGEEGPPEYIWEALDLLKVERI 218 Query: 239 GHACF--FKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDD 296 H + +L +IP+ +C SN + H D+ + + +DD Sbjct: 219 DHGVRAFEDERLMRRLIDEQIPLTVCPLSNTKLCVFDDMSQHTILDMLERGVKVTVNSDD 278 Query: 297 FGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAED 337 F ++ + +SLG+++ + LA+ ++DA ++ Sbjct: 279 PAYFGGYVTENFHALQQSLGMTEEQARRLAQNSLDARLVKE 319 >4GXW-A nrPDB Length = 380 Score = 291 bits (744), Expect = 3e-79, Method: Composition-based stats. Identities = 77/353 (21%), Positives = 134/353 (37%), Gaps = 36/353 (10%) Query: 3 WIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSLVEVFKLFD 62 + +LPK+ELH HL G++R T + LA+ G I A+++ + ++ + + L Sbjct: 25 FFHALPKVELHCHLLGAVRHDTFVALAQRSGAP--IERAEIDAFYARGEKPVGVLHVLRA 82 Query: 63 LIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSI-GMSKRSYMEAVIQGLR 121 L L T + RI E +ED A NV + E P + + G+ A++ G+R Sbjct: 83 LDRYLLTRPDDLRRIAYEYLEDAAAHNVRHAEFFWNPTGTVRVSGIPYADAQAAIVTGMR 142 Query: 122 SVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMR-- 179 + I RL+ SIDR + + A+ V R Sbjct: 143 DAAR----------------------DFGIGARLIPSIDREQDPDEAVAIVDWMKANRAD 180 Query: 180 DVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNP-KEIQAMLD-FKPHR 237 +V +GID N E F A + A+ T H GE P + ++ +D R Sbjct: 181 EVAGIGIDYRENDRPPEL--FWKAYRDARAAGFRTTAHAGEFGMPWRNVETAVDLLHVDR 238 Query: 238 IGHACFFKD--EDWTKLKSFRIPVEICLTSNIVTKSISSI---DIHHFADLYNAKHPLIL 292 + H D E + I + T++ +++ + H + + Sbjct: 239 VDHGYTIVDNPELCARYAERGIVFTVVPTNSYYLRTLPPDQWAERHPMRKMPGLGLKIHP 298 Query: 293 CTDDFGVFSTSLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLRF 345 TDD + + S + L G + ++ ID + +D+ K R Sbjct: 299 NTDDPTLHKVNPSEAWELMFSHFGFTIADLKQFMLNGIDGAWVDDDTKAAWRA 351 >3RYS-A nrPDB Length = 343 Score = 289 bits (740), Expect = 9e-79, Method: Composition-based stats. Identities = 72/341 (21%), Positives = 135/341 (39%), Gaps = 31/341 (9%) Query: 8 PKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRS-LVEVFKLFDLIHK 66 P ELH H+ G+++ + LA G + + + D+E + +K + + L L+ Sbjct: 14 PVAELHLHIEGTLQPELIFALAERNGIE--LPYEDIEELREKYEFTDLQSFLDLYYANMA 71 Query: 67 LTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLRSVSEV 126 + + T +TR +E A V + E+ P+ S G++ + + V L + E Sbjct: 72 VLQTEQDFTDMTRAYLERAAAGGVRHAEIMMDPQAHTSRGVALETCVNGVANALATSEE- 130 Query: 127 DIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMR-DVGVVG 185 + L+ + R + +SA+E + L M + +G Sbjct: 131 ---------------------DFGVSTLLIAAFLRDMSEDSALEVLDQLLAMHAPIAGIG 169 Query: 186 IDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLD-FKPHRIGHA--C 242 +D + + S F Q A + L H GE I LD RI H C Sbjct: 170 LDSA--EVGNPPSKFERLYQRAAEAGLRRIAHAGEEGPASYITEALDVLHVERIDHGIRC 227 Query: 243 FFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFGVFST 302 + +L + ++P+ +C SN+ +++ + H ++ + + +DD F Sbjct: 228 MEDTDVVQRLVAEQVPLTVCPLSNVRLRAVDKLADHPLPEMLAIGLNVCVNSDDPAYFGG 287 Query: 303 SLSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQL 343 + + + V+ L S E LA +I ++FA D K L Sbjct: 288 YVDDNFEQLVKVLEFSVPEQATLAANSIRSSFASDARKAVL 328 >3LGD-A nrPDB Length = 508 Score = 231 bits (588), Expect = 4e-61, Method: Composition-based stats. Identities = 80/321 (24%), Positives = 127/321 (39%), Gaps = 47/321 (14%) Query: 57 VFKLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAV 116 F + LIH V R +E ED NV+Y+E+R + +S + E Sbjct: 185 FFTISGLIHYAPVFRDYVFRSMQEFYED----NVLYMEIRA--RLLPVYELSGEHHDEE- 237 Query: 117 IQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLAL 176 +++ EV FV + IG K IY S R + E++++A+ Sbjct: 238 -WSVKTYQEVAQKFVETHP--------EFIGIKIIY-----SDHRSKDVAVIAESIRMAM 283 Query: 177 EMR---DVGVVGIDLSGNPLVGE-WSTFLPALQYAKDND--LHITLHCGEVPNP-----K 225 +R V G DL G+ G + AL + L H GE + Sbjct: 284 GLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDR 343 Query: 226 EIQAMLDFKPHRIGHACFFKDEDWTKLKSFR--IPVEICLTSNIVTKSISSIDIHHFADL 283 I L RIGH + S++ IP+E+C SN V K +S + H A L Sbjct: 344 NILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATL 403 Query: 284 YNAKHPLILCTDDFGVFS-TSLSNEYALAVRSLGLSKSETFALARAAIDA---------- 332 HP+++ +DD +F LS ++ +G K++ L + A+++ Sbjct: 404 MATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESE 463 Query: 333 --TFAEDEVKQQLRFIFDSAS 351 TF E K+ +FI D A+ Sbjct: 464 KNTFMEIWKKRWDKFIADVAT 484 >2A3L-A nrPDB Length = 701 Score = 48.7 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 60/197 (30%), Gaps = 39/197 (19%) Query: 183 VVGIDLSGNPLVGEWST-------------FLPALQY--------------AKDNDLHIT 215 VVG DL + E F PA Y +++ T Sbjct: 456 VVGFDLVDDESKPERRPTKHMPTPAQWTNAFNPAFSYYVYYCYANLYVLNKLRESKGMTT 515 Query: 216 L----HCGEVPNPKEIQAMLDFKPHRIGHACFFKDEDWTKLKSF--RIPVEICLTSNIVT 269 + H GE + + A H I H + + + +I + + SN Sbjct: 516 ITLRPHSGEAGDIDHL-AATFLTCHSIAHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSL 574 Query: 270 KSISSIDIHHFADLYNAKHPLILCTDDFG---VFSTSLSNEYALAVRSLGLSKSETFALA 326 + F + + L TDD + L EY++A LS + +A Sbjct: 575 --FLDYHRNPFPVFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSACDLCEIA 632 Query: 327 RAAIDATFAEDEVKQQL 343 R ++ + +K Sbjct: 633 RNSVYQSGFSHALKSHW 649 >2BB0-A nrPDB Length = 421 Score = 44.4 bits (103), Expect = 8e-05, Method: Composition-based stats. Identities = 36/319 (11%), Positives = 86/319 (26%), Gaps = 34/319 (10%) Query: 17 NGSIRDSTLLELARVLGEKGVIVFADVEHVIQKNDRSL------VEVFKLFDLIHKLTTD 70 +++ + L G++ ++ + + + + + Sbjct: 56 EAGYEADEIIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLDILAQGGGILST 115 Query: 71 HKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLRSVSEVDIDF 130 K + E + A +S + V G E ++ Sbjct: 116 VKDTRAASEEELLQKA-------------HFHLQRMLSYGTTTAEVKSGYGLEKETELKQ 162 Query: 131 VTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMRDVGVVGI-DLS 189 + + D + + + + + + + + L E+++ + D+ Sbjct: 163 LRVAKKLHESQPVDLVSTF-MGAHAIPPEYQNDPDDFLDQMLSLLPEIKEQELASFADIF 221 Query: 190 GNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGHACFFKDEDW 249 V S LQ A + + +H E+ + K H DE Sbjct: 222 TETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGKLKAVSADHLVGTSDEGI 281 Query: 250 TKLKSFRIPVEICLTSNIVTKSISSIDIHHFAD-LYNAKHPLILCTD-DFGVFSTSLSNE 307 KL + + + A + + + L TD + G +S + Sbjct: 282 KKLAEAGTIAVLLPGTTFYLG----KSTYARARAMIDEGVCVSLATDFNPG---SSPTEN 334 Query: 308 YAL----AVRSLGLSKSET 322 L A L ++ E Sbjct: 335 IQLIMSIAALHLKMTAEEI 353 >2OOF-A nrPDB Length = 416 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 48/161 (29%), Gaps = 5/161 (3%) Query: 186 IDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGHACFFK 245 +D+ + + A L + H ++ N +F + H + Sbjct: 211 VDVFCEHIGFSLAQTEQVYLAADQYGLAVKGHMDQLSNLGGSTLAANFGALSVDHLEYLD 270 Query: 246 DEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD-DFGVF-STS 303 E L + + T+ K + L A P+ + +D + G S Sbjct: 271 PEGIQALAHRGVVATLLPTAFYFLKETK---LPPVVALRKAGVPMAVSSDINPGTAPIVS 327 Query: 304 LSNEYALAVRSLGLSKSETFALARAAIDATFAEDEVKQQLR 344 L +A GL+ E A E E QLR Sbjct: 328 LRMAMNMACTLFGLTPVEAMAGVTRHAARALGEQEQLGQLR 368 >2I9U-A nrPDB Length = 439 Score = 37.1 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 21/61 (34%), Gaps = 4/61 (6%) Query: 235 PHRIGHACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCT 294 P + H E+ +K + + C TSN S + N ++L + Sbjct: 264 PTLMAHCIHSSKEEINLIKRNNVTIVHCPTSNFNLGS----GMMPVRKYLNLGINVVLGS 319 Query: 295 D 295 D Sbjct: 320 D 320 >2PAJ-A nrPDB Length = 492 Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 18/56 (32%), Gaps = 4/56 (7%) Query: 240 HACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 H ++ L V C SN S I ++ +A P+ + D Sbjct: 285 HLVKVDADEIALLAQTGTGVAHCPQSNGRLGS----GICPVREMADAGVPVSIGVD 336 >2Z9W-A nrPDB Length = 392 Score = 32.9 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 39/127 (30%), Gaps = 11/127 (8%) Query: 60 LFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQG 119 L L + D+ ++ E V D A + +R + K G A Sbjct: 25 LRGLGRTVLYDYDPAFQLLYEKVVDKAQKA-----MRLSNKPVILHGEPVLGLEAA---- 75 Query: 120 LRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEMR 179 + S + D V + + ++ G G K+ LL + Sbjct: 76 --AASLISPDDVVLNLASGVYGKGFGYWAKRYSPHLLEIEVPYNEAIDPQAVADMLKAHP 133 Query: 180 DVGVVGI 186 ++ VV + Sbjct: 134 EITVVSV 140 >3ROR-A nrPDB Length = 291 Score = 32.5 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 31/211 (14%), Positives = 52/211 (24%), Gaps = 32/211 (15%) Query: 21 RDSTLLELARVLGEKGVIVFADVEHVIQKN---DRSLVEVFKLFDLIHKLTTDHKTVTRI 77 R + + ++G + VI+K R + RI Sbjct: 30 RPE---YVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRI 86 Query: 78 TREVVEDFALENVVYLELRTTPKRSDSIGMSK---RSYMEAVIQGLRSVSEVDIDFVTAS 134 E + D P G K S E + G+ + + + Sbjct: 87 AHEYLVDNGAY----------PSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNI 136 Query: 135 DSQKLHNAGDGIGRKKIYVRLLLSIDR---RETTESAMETVKLALEMRDVGVVGIDLSGN 191 D G + R T E+ M + R + V+G Sbjct: 137 DVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIG------ 190 Query: 192 PLVGEWSTFLPALQYAKD---NDLHITLHCG 219 V E +D + + T H G Sbjct: 191 -RVIESYANRFGYNVVRDFTGHGIGTTFHNG 220 >2OOD-A nrPDB Length = 475 Score = 31.3 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 14/33 (42%) Query: 239 GHACFFKDEDWTKLKSFRIPVEICLTSNIVTKS 271 GH + + ++ ++ V C SN+ S Sbjct: 272 GHGVYLSNNEFRRMSKKGAAVVFCPCSNLFLGS 304 >3E0L-A nrPDB Length = 455 Score = 31.3 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 47/156 (30%), Gaps = 29/156 (18%) Query: 161 RRETTESAMETVKLALEMRDVGVVGIDLSGNPLVGEWSTFLPALQY-----AKDNDLHIT 215 + T ES ET + EM P+V + L AK DLHI Sbjct: 184 KETTEESIKETERFVSEMLQKNY----SRVKPIVTPGNGVSETLMGELGNIAKTRDLHIQ 239 Query: 216 LHCGE--------------VPNPKEIQAMLDFKPHR--IGHACFFKDEDWTKLKSFRIPV 259 H E N + + ++ + H C+ E+ + Sbjct: 240 SHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASI 299 Query: 260 EICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 C SN+ S + ++ + + L TD Sbjct: 300 AHCPNSNLSLSS----GFLNVLEVLKHEVKIGLGTD 331 >4DYK-A nrPDB Length = 451 Score = 31.3 bits (69), Expect = 0.65, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 18/56 (32%), Gaps = 4/56 (7%) Query: 240 HACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 H ++D L V C SN+ S L+ A + + TD Sbjct: 258 HMTQVDNDDLAMLVETNSSVIHCPESNLKLAS----GFCPVEKLWQAGVNVAIGTD 309 >4V1Y-A nrPDB Length = 494 Score = 31.0 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 37/114 (32%), Gaps = 16/114 (14%) Query: 193 LVGEWSTFLPALQYAKDNDLHITLHCGEVP--------NPKEIQAMLDFKPHR--IGHAC 242 + E + A A+D + TLH E +P E R + H Sbjct: 241 VTVEGMRWAQAF--ARDRAVMWTLHMAESDHDERIHGMSPAEYMECYGLLDERLQVAHCV 298 Query: 243 FFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDD 296 +F +D L + V + SN S + ++ + + TD+ Sbjct: 299 YFDRKDVRLLHRHNVKVASQVVSNAYLGS----GVAPVPEMVERGMAVGIGTDN 348 >2PUZ-A nrPDB Length = 419 Score = 31.0 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 14/124 (11%), Positives = 32/124 (25%), Gaps = 4/124 (3%) Query: 176 LEMRDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKP 235 + +D + A+ L + LH ++ N + + Sbjct: 213 KAHAEGLADAVDGFCEGIAFSVKEIDRVFAAAQQRGLPVKLHAEQLSNLGGAELAASYNA 272 Query: 236 HRIGHACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTD 295 H + + L + + + + L +A + L TD Sbjct: 273 LSADHLEYLDETGAKALAKAGTVAVLLPGAFYALR---EKQLPPVQALRDAGAEIALATD 329 Query: 296 -DFG 298 + G Sbjct: 330 CNPG 333 >4CJ9-A nrPDB Length = 794 Score = 30.6 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 20/134 (14%), Positives = 46/134 (34%), Gaps = 8/134 (5%) Query: 121 RSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETV-KLALEMR 179 +++++ + A Q + + + + + + A++TV L +R Sbjct: 283 ATIAKIAGNIGGAQALQTVLDLEPALCERGFSQATIAKMAGNNGGAQALQTVLDLEPALR 342 Query: 180 DVGVVGIDL---SGNPLVGE-WSTFLPALQYAKDNDLH---ITLHCGEVPNPKEIQAMLD 232 D+ +GN + + + + + I G + + +QA+LD Sbjct: 343 KRDFRQADIIKIAGNDGGAQALQAVIEHGPTLRQHGFNLADIVKMAGNIGGAQALQAVLD 402 Query: 233 FKPHRIGHACFFKD 246 KP H D Sbjct: 403 LKPVLDEHGFSQPD 416 >4TO8-A nrPDB Length = 292 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 42/148 (28%), Gaps = 11/148 (7%) Query: 102 SDSIGMSKRSYMEAVIQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDR 161 G S EA+ G SV + + K + V L Sbjct: 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVG 142 Query: 162 RETTESAMETV-----KLALEMRDVGVV-----GIDLSGNPLVGEWST-FLPALQYAKDN 210 + + + + K E+ + + + P GE F + Sbjct: 143 GQEDDVVADGIIYADPKECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLST 202 Query: 211 DLHITLHCGEVPNPKEIQAMLDFKPHRI 238 L + LH G K+IQ + F +I Sbjct: 203 GLPLVLHGGTGIPTKDIQKAIPFGTAKI 230 >3Q94-A nrPDB Length = 288 Score = 29.4 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 43/148 (29%), Gaps = 11/148 (7%) Query: 102 SDSIGMSKRSYMEAVIQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDR 161 G S EA+ G SV + + + + + V L Sbjct: 86 HLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVG 145 Query: 162 RETTESAMETV---KLALEMRDVGVVGID-------LSGNPLVGEWSTFLPALQYAKD-N 210 + + E V A V GID P GE + ++ +D Sbjct: 146 GQEDDVIAEGVIYADPAECKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFT 205 Query: 211 DLHITLHCGEVPNPKEIQAMLDFKPHRI 238 + + LH G +I+ + +I Sbjct: 206 GVPLVLHGGTGIPTADIEKAISLGTSKI 233 >2IDA-A nrPDB Length = 102 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 19/51 (37%) Query: 247 EDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDF 297 E+ K+ S + + IC T V S H + HP+I D Sbjct: 22 EECLKIGSPWVHLRICRTCGHVGCCDDSPHKHATRHFHATGHPIIEGYDPP 72 >3I6S-A nrPDB Length = 649 Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 23/69 (33%), Gaps = 1/69 (1%) Query: 263 LTSNIVTKSISSIDIHHFADL-YNAKHPLILCTDDFGVFSTSLSNEYALAVRSLGLSKSE 321 N S + L A H D G+ + +Y + SL ++ + Sbjct: 461 PLDNTRKPIKDSDNNKAATPLDMGAGHVDPNRALDPGLVYDATPQDYVNLLCSLNFTEEQ 520 Query: 322 TFALARAAI 330 +AR++ Sbjct: 521 FKTIARSSA 529 >2NX9-A nrPDB Length = 464 Score = 29.0 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 49/132 (37%), Gaps = 8/132 (6%) Query: 116 VIQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLA 175 V + +++ +V F +D + + A + + + + L + V +A Sbjct: 106 VERAVKNGMDVFRVFDAMNDVRNMQQALQAVKKMGAHAQGTLCY-TTSPVHNLQTWVDVA 164 Query: 176 LEMRDVGVVGI---DLSGNPLVGEWSTFLPALQYAKDNDLHITLH--CGEVPNPKEIQAM 230 ++ ++GV I D++G + L+ D +LH+ H G + Sbjct: 165 QQLAELGVDSIALKDMAGILTPYAAEELVSTLKKQVDVELHLHCHSTAGLADM--TLLKA 222 Query: 231 LDFKPHRIGHAC 242 ++ R+ A Sbjct: 223 IEAGVDRVDTAI 234 >4R7W-A nrPDB Length = 431 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 49/317 (15%), Positives = 84/317 (26%), Gaps = 69/317 (21%) Query: 8 PKIELHAHLNGSI--------RDSTLLE-LARVLGEKGVIVFADVEHVIQKNDRSLVEVF 58 P +E H HL+ ++ R TL E + R K I D K L + Sbjct: 51 PFVEPHIHLDATLTAGEPEWNRSGTLFEGITRWSQRKASITPEDTRQRALKTIGMLRDFG 110 Query: 59 KLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQ 118 H TD V+ A + + + + +S + A+ Sbjct: 111 VQHVRTHVDVTDPSLAALQALLAVKQEAADLIDLQIVAFPQEGIESYPNGRELMTRAIEM 170 Query: 119 GLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTESAMETVKLALEM 178 G V + T R + S M + LA Sbjct: 171 GADVVGGIPHYENT----------------------------RDKGVSSVMFLMDLAQRY 202 Query: 179 RDVGVVGIDLSGNPLVGEWSTFLPAL---QYAKDNDLHITL-HCGEVPNPKEIQAMLDFK 234 + +D+ + + S FL L + +T H + + Sbjct: 203 GRL----VDVHCDEIDDPQSRFLEVLAEEARVRGMGAQVTASHTCAMGSYDNAYCS---- 254 Query: 235 PHRIGHACFFKDEDWTKLKSFRIPVEICLTSNIVTK----SISSID-IHHFADLYNAKHP 289 + + LK+ I C T +I + S + A+L A Sbjct: 255 ------------KLFRLLKASGINFISCPTESIHLQGRFDSWPKRRGVTRVAELDRAGIN 302 Query: 290 LILCTD---DFGVFSTS 303 + D D + Sbjct: 303 VCFAQDSIQDPWYPLGN 319 >1N0W-A nrPDB Length = 243 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 13/32 (40%) Query: 17 NGSIRDSTLLELARVLGEKGVIVFADVEHVIQ 48 G+ R LL +A G G V +V + Sbjct: 67 EGTFRPERLLAVAERYGLSGSDVLDNVAYARA 98 >5H1C-A nrPDB Length = 339 Score = 28.6 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 13/32 (40%) Query: 17 NGSIRDSTLLELARVLGEKGVIVFADVEHVIQ 48 G+ R LL +A G G V +V + Sbjct: 163 EGTFRPERLLAVAERYGLSGSDVLDNVAYARA 194 >1H54-A nrPDB Length = 754 Score = 28.3 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 10/80 (12%), Positives = 25/80 (31%), Gaps = 11/80 (13%) Query: 280 FADLYNAKHPLILCTDDFGVFSTSLSNEYA-----------LAVRSLGLSKSETFALARA 328 + + + + + + + ++EY LA +L + + + Sbjct: 460 ISRFWADRVHFSKRNNQYMIHGVTGADEYENNVDNNWDTNMLAQWTLKYTLEILGKVDQD 519 Query: 329 AIDATFAEDEVKQQLRFIFD 348 DE K + + I D Sbjct: 520 TAKQLDVSDEEKTKWQDIVD 539 >1H4S-A nrPDB Length = 477 Score = 27.9 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 37/122 (30%), Gaps = 15/122 (12%) Query: 108 SKRSYMEAVIQGLRSVSEVDIDFVTASDSQKLHNAGDGIGRKKIYVRLLLSIDRRETTES 167 + E ++G+ E+ + + A G++ + + L + Sbjct: 332 PGYKFHEWELKGVPFRVELGPKDLE---GGQAVLASRLGGKETLPLAALPEALPGKLDAF 388 Query: 168 AMETVKLALEMRDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEI 227 E + AL R+ +D A + A + HCG+ + I Sbjct: 389 HEELYRRALAFREDHTRKVDT------------YEAFKEAVQEGFALAFHCGDKACERLI 436 Query: 228 QA 229 Q Sbjct: 437 QE 438 >3V7P-A nrPDB Length = 427 Score = 27.9 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 28/77 (36%), Gaps = 10/77 (12%) Query: 240 HACFFKDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHFADLYNAK-HPLILCTDDFG 298 H + +E+ + S+ + C SN + + DL K P + TD G Sbjct: 257 HMVWANEEEIQTIASYNAHIIHCPISNRLLGN-------GVLDLEKIKSIPYAIATD--G 307 Query: 299 VFSTSLSNEYALAVRSL 315 + S N Y +L Sbjct: 308 LSSNYSLNMYEELKAAL 324 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.120 0.293 Lambda K H 0.267 0.0367 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,909,500 Number of Sequences: 36641 Number of extensions: 367276 Number of successful extensions: 1238 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1101 Number of HSP's gapped (non-prelim): 62 length of query: 355 length of database: 10,336,785 effective HSP length: 98 effective length of query: 257 effective length of database: 6,745,967 effective search space: 1733713519 effective search space used: 1733713519 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.5 bits)