BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8LAS7 (226 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2ZFD-A nrPDB 461 e-131 1UHN-A nrPDB 383 e-107 1V1G-A nrPDB 251 3e-67 6EPA-A nrPDB 79 2e-15 4IL1-A nrPDB 79 2e-15 4ORC-B nrPDB 78 3e-15 2L2E-A nrPDB 75 3e-14 5B8I-B nrPDB 73 1e-13 5M6C-E nrPDB 72 2e-13 2LCP-A nrPDB 70 6e-13 5T7C-A nrPDB 69 2e-12 5YPX-A nrPDB 69 2e-12 3DD4-A nrPDB 69 2e-12 1S6C-A nrPDB 67 9e-12 1S1E-A nrPDB 66 9e-12 1BJF-A nrPDB 64 6e-11 2E30-A nrPDB 62 2e-10 1DGU-A nrPDB 59 2e-09 2LM5-A nrPDB 59 2e-09 2JUL-A nrPDB 59 2e-09 2JU0-A nrPDB 58 3e-09 2BEC-A nrPDB 54 5e-08 2NA0-A nrPDB 53 1e-07 2GGZ-A nrPDB 53 1e-07 2R2I-A nrPDB 51 3e-07 2I94-A nrPDB 49 1e-06 2D8N-A nrPDB 48 3e-06 5A2H-A nrPDB 46 1e-05 5ZOR-A nrPDB 44 7e-05 2L1W-A nrPDB 43 1e-04 3EK4-A nrPDB 43 1e-04 6O20-F nrPDB 42 2e-04 1JBA-A nrPDB 42 2e-04 3WFN-B nrPDB 42 2e-04 2N6A-A nrPDB 41 4e-04 6HCS-A nrPDB 41 4e-04 4E53-A nrPDB 41 4e-04 2F2P-A nrPDB 41 4e-04 5I0I-E nrPDB 40 7e-04 4OY4-A nrPDB 40 8e-04 3U0K-A nrPDB 40 0.001 3KF9-A nrPDB 40 0.001 2LMV-A nrPDB 39 0.002 1GGZ-A nrPDB 39 0.002 1CLM-A nrPDB 38 0.003 5PAL-A nrPDB 37 0.005 5ZGM-A nrPDB 37 0.005 2Q4U-A nrPDB 36 0.011 1S6I-A nrPDB 36 0.011 1DTL-A nrPDB 36 0.015 2E6W-A nrPDB 36 0.015 1OZS-A nrPDB 35 0.020 6IIE-A nrPDB 35 0.038 4JWQ-A nrPDB 34 0.041 2KN2-A nrPDB 34 0.056 5UKG-A nrPDB 34 0.066 2RO9-A nrPDB 33 0.067 2AAO-A nrPDB 33 0.091 3K21-A nrPDB 33 0.11 2G9B-A nrPDB 33 0.11 4I2Y-A nrPDB 33 0.12 2WCE-A nrPDB 33 0.12 1TOP-A nrPDB 32 0.15 2LUC-A nrPDB 32 0.18 4ZCV-A nrPDB 32 0.19 1QLS-A nrPDB 32 0.19 5D43-A nrPDB 32 0.19 1IYJ-B nrPDB 32 0.20 5E37-A nrPDB 32 0.21 4N5X-A nrPDB 32 0.21 2KQY-A nrPDB 32 0.22 3QRX-A nrPDB 32 0.22 3PAT-A nrPDB 32 0.23 2ROB-A nrPDB 32 0.26 4WPX-A nrPDB 32 0.26 6I8Y-A nrPDB 32 0.28 2TN4-A nrPDB 32 0.30 2NS2-A nrPDB 32 0.32 2GGM-A nrPDB 32 0.32 5MWC-D nrPDB 31 0.36 1JC2-A nrPDB 31 0.44 2NCO-A nrPDB 31 0.45 2M97-A nrPDB 31 0.45 2OBH-A nrPDB 31 0.49 4RGJ-A nrPDB 30 0.61 2IO3-A nrPDB 30 0.68 1NSH-A nrPDB 30 0.68 2BL0-C nrPDB 30 0.76 1FW4-A nrPDB 30 0.86 2M5E-A nrPDB 30 0.87 4YZB-A nrPDB 30 1.2 2M29-A nrPDB 30 1.2 1JF0-A nrPDB 29 1.4 5ZH6-A nrPDB 29 1.4 1A75-A nrPDB 29 1.4 2Z23-A nrPDB 29 1.6 2KYF-A nrPDB 29 1.8 1M39-A nrPDB 29 1.9 1BU3-A nrPDB 29 2.0 2KZ2-A nrPDB 28 2.8 5DJ4-A nrPDB 28 2.9 5CPV-A nrPDB 28 2.9 3AAJ-A nrPDB 28 3.0 1TIZ-A nrPDB 28 3.0 1Q80-A nrPDB 28 3.6 2PMY-A nrPDB 28 3.6 5JN2-A nrPDB 28 3.9 3KPX-A nrPDB 28 4.1 2JXC-A nrPDB 28 4.4 2LV7-A nrPDB 27 4.9 5XND-A nrPDB 27 5.0 5LUG-A nrPDB 27 5.0 3TZ1-A nrPDB 27 6.7 1NYA-A nrPDB 27 7.1 3O4Y-A nrPDB 27 7.6 2K2I-A nrPDB 27 8.0 4MSP-A nrPDB 27 8.3 1S36-A nrPDB 27 8.7 >2ZFD-A nrPDB Length = 226 Score = 461 bits (1187), Expect = e-131, Method: Compositional matrix adjust. Identities = 226/226 (100%), Positives = 226/226 (100%) Query: 1 MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSA 60 MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSA Sbjct: 1 MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSA 60 Query: 61 VIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 VIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI Sbjct: 61 VIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD Sbjct: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 Query: 181 GKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT 226 GKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT Sbjct: 181 GKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT 226 >1UHN-A nrPDB Length = 189 Score = 383 bits (984), Expect = e-107, Method: Compositional matrix adjust. Identities = 189/189 (100%), Positives = 189/189 (100%) Query: 32 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 91 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 60 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT Sbjct: 61 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 120 Query: 152 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDIT 211 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDIT Sbjct: 121 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDIT 180 Query: 212 TTFPSFVFH 220 TTFPSFVFH Sbjct: 181 TTFPSFVFH 189 >1V1G-A nrPDB Length = 222 Score = 251 bits (640), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 119/200 (59%), Positives = 157/200 (78%) Query: 26 QSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL 85 + G DPELLA T F+V E+EALYELFKK+SS++IDDGLI+KEEFQLALF+ + +L Sbjct: 15 RPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNL 74 Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 FADR+FD+FD K NG++ F EF R+L VFHP+AP+ +K+ F+F+LYDL+Q GFIER+E+K Sbjct: 75 FADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELK 134 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 +MVVA L ES + L + +IE ++DK F +AD K+DGKID +EW+ V +PSL+KNMTL Sbjct: 135 EMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKNMTLP 194 Query: 206 YLKDITTTFPSFVFHSQVED 225 YLKDI TFPSFV + E+ Sbjct: 195 YLKDINRTFPSFVSSCEEEE 214 >6EPA-A nrPDB Length = 187 Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFK---TNKKESLFADRVFD 92 L DT F+ EI ++ F K +GL+ ++ F + ++K + S FA VF Sbjct: 16 LTTDTYFTEKEIRQWHKGFLKDCP----NGLLTEQGF-IKIYKQFFPDGDPSKFASLVFR 70 Query: 93 LFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATL 152 +FD ++G + FEEF RALS+ +D+K+H++F+LYD+ G+I R+E+ +V A Sbjct: 71 VFDENNDGAIEFEEFIRALSI-TSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIY 129 Query: 153 AESGMNLK---DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + + + +DK F++ D HD ++ EE+R P +++ ++L Sbjct: 130 QMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSL 184 >4IL1-A nrPDB Length = 823 Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 8/151 (5%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 F EI+ L + FKK+ + + G ++ EEF + +++ RV D+FDT NG Sbjct: 172 FDADEIKRLGKRFKKLD--LDNSGSLSVEEF---MSLPELQQNPLVQRVIDIFDTDGNGE 226 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ + G NLKD Sbjct: 227 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV---GNNLKD 283 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 T ++ I+DKT AD DG+I EE+ ++V Sbjct: 284 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 10 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 63 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 115 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >4ORC-B nrPDB Length = 170 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 52/151 (34%), Positives = 88/151 (58%), Gaps = 8/151 (5%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 F EI+ L + FKK+ + + G ++ EEF ++L + +++ RV D+FDT NG Sbjct: 15 FDADEIKRLGKRFKKLD--LDNSGSLSVEEF-MSLPEL--QQNPLVQRVIDIFDTDGNGE 69 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ + G NLKD Sbjct: 70 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV---GNNLKD 126 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 T ++ I+DKT AD DG+I EE+ ++V Sbjct: 127 TQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 >2L2E-A nrPDB Length = 190 Score = 74.7 bits (182), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 87/175 (49%), Gaps = 11/175 (6%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDL 93 L R T F E++ Y+ F K + G +NK EFQ F S FA+ VF++ Sbjct: 16 LVRSTRFDKKELQQWYKGFFKDCPS----GHLNKSEFQKIYKQFFPFGDPSAFAEYVFNV 71 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 FD NG + F+EF ALSV ++DK+ ++FQLYDL G I E+ ++V A Sbjct: 72 FDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 Query: 154 ESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G +K ED ++K F D DG++ EE+ R P+++ ++L Sbjct: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 >5B8I-B nrPDB Length = 171 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 54/166 (32%), Positives = 88/166 (53%), Gaps = 15/166 (9%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 F E++ L++ F K+ G I ++EF L+L + + + R+ +FD G Sbjct: 15 FDHEEVDRLWKRFMKLDRD--KSGTIERDEF-LSLPQVSSNP--LSTRMIAIFDEDGGGD 69 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE---VKQMVVATLAESGMN 158 + F+EF LS F ++K+ F+F++YD+ + GFI E V +M+V G N Sbjct: 70 VDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMV------GSN 123 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 LKD ++ I+DKT EAD DG+I EE+ +V + + +MTL Sbjct: 124 LKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMV-ENTDVSMSMTL 168 >5M6C-E nrPDB Length = 193 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 14/177 (7%) Query: 33 PELLA---RDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFA 87 PE+L +T FS E++ Y+ F K G++N +EF+ A F S FA Sbjct: 10 PEMLQDLRENTEFSELELQEWYKGFLKDCPT----GILNVDEFKKIYANFFPYGDASKFA 65 Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 + VF FDT +G + F EF ALSV ++ K+ ++F +YDL G+I R+E+ ++ Sbjct: 66 EHVFRNFDTNSDGTIDFREFIIALSV-TSRGRLEQKLMWAFSMYDLDGNGYISREEMLEI 124 Query: 148 VVA--TLAESGMNLK--DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 V A + S M + ++ E +K F + DT +DGK+ EE+ PS+++ Sbjct: 125 VQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVR 181 >2LCP-A nrPDB Length = 190 Score = 70.5 bits (171), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 54/176 (30%), Positives = 87/176 (49%), Gaps = 9/176 (5%) Query: 34 ELLARDTVFSVSEIEALYELF-KKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFD 92 E L R T F+ E++ Y+ F K S +D K Q F K FA VF+ Sbjct: 14 EELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTK---FATFVFN 70 Query: 93 LFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATL 152 +FD +G + F EF +ALSV +D+K+ ++F+LYDL G+I R E+ +V A Sbjct: 71 VFDENKDGRIEFSEFIQALSV-TSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIY 129 Query: 153 AESGMNL----KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + ++ E +D+ F D DGK+ +E++ PS+++ ++L Sbjct: 130 QMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSL 185 >5T7C-A nrPDB Length = 193 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 56/177 (31%), Positives = 89/177 (50%), Gaps = 14/177 (7%) Query: 33 PELLA---RDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFA 87 PE+L +T F+ E++ Y+ F K G + +EF+ A F S FA Sbjct: 10 PEVLQDLRENTEFTDHELQEWYKGFLKDCPT----GHLTVDEFKKIYANFFPYGDASKFA 65 Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 + VF FDT +G + F EF ALSV ++ K+ ++F +YDL G+I R E+ ++ Sbjct: 66 EHVFRTFDTNGDGTIDFREFIIALSV-TSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEI 124 Query: 148 VVA--TLAESGMNLK--DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 V A + S M + ++ E DK F + DT +DGK+ EE+ PS+++ Sbjct: 125 VQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVR 181 >5YPX-A nrPDB Length = 223 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 47/161 (29%), Positives = 83/161 (51%), Gaps = 7/161 (4%) Query: 42 FSVSEIEALYELFKKISSAV-IDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNG 100 F+ +E+E+L +K + + +D L Q K N E L DRVF FD + Sbjct: 41 FTKTEVESLIICYKNLLEGLKMDRNLFRDILHQ----KFNMTEDLLMDRVFRAFDKDSDS 96 Query: 101 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL- 159 + E+ LSVF +D+K+ ++F ++DL G+I R+E+ QM+ L + Sbjct: 97 YISLTEWVEGLSVF-LRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPTEED 155 Query: 160 KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 D I+D+++ ++ D HD ++ K++++ VL P LL+ Sbjct: 156 PDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLIEPLLLE 196 >3DD4-A nrPDB Length = 229 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 46/177 (25%), Positives = 92/177 (51%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 ELL + F+ E++ LY FK + G++N+E F+ + F + +A +F Sbjct: 53 ELLEAQSKFTKKELQILYRGFKNECPS----GVVNEETFKEIYSQFFPQGDSTTYAHFLF 108 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FDT HNG + FE+F + LS+ + +K++++F LYD+ + G+I ++E+ ++ A Sbjct: 109 NAFDTDHNGAVSFEDFIKGLSIL-LRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAI 167 Query: 152 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + ED ++ F++ D DG + +E+ + +++++M L Sbjct: 168 YDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQL 224 >1S6C-A nrPDB Length = 183 Score = 66.6 bits (161), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L T F+ E++ LY FK + G++N+E F+ A F + S +A +F Sbjct: 7 EQLEAQTNFTKRELQVLYRGFKNECPS----GVVNEETFKQIYAQFFPHGDASTYAHYLF 62 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FDT G + FE+F ALS+ + +K+ ++F LYD+ + G+I ++E+ +V A Sbjct: 63 NAFDTTQTGSVKFEDFVTALSIL-LRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 121 Query: 152 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + ED +D F++ D DG + +E+ ++++++ L Sbjct: 122 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQL 178 >1S1E-A nrPDB Length = 224 Score = 66.2 bits (160), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L T F+ E++ LY FK + G++N+E F+ A F + S +A +F Sbjct: 40 EQLEAQTNFTKRELQVLYRGFKNECPS----GVVNEETFKQIYAQFFPHGDASTYAHYLF 95 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FDT G + FE+F ALS+ + +K+ ++F LYD+ + G+I ++E+ +V A Sbjct: 96 NAFDTTQTGSVKFEDFVTALSIL-LRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 154 Query: 152 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + ED +D F++ D DG + +E+ ++++++ L Sbjct: 155 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQL 211 >1BJF-A nrPDB Length = 193 Score = 63.5 bits (153), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 14/177 (7%) Query: 33 PEL---LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFA 87 PE+ L T F+ EI+ Y+ F + + G ++ EEF+ F S FA Sbjct: 10 PEVMQDLLESTDFTEHEIQEWYKGFLRDCPS----GHLSMEEFKKIYGNFFPYGDASKFA 65 Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 + VF FD +G + F EF ALSV ++ K+ ++F +YDL G+I + E+ ++ Sbjct: 66 EHVFRTFDANGDGTIDFREFIIALSV-TSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEI 124 Query: 148 VVA--TLAESGMNLK--DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 V A + S M + ++ E +K F + DT DGK+ EE+ PS+++ Sbjct: 125 VQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVR 181 >2E30-A nrPDB Length = 195 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 57/199 (28%), Positives = 96/199 (48%), Gaps = 34/199 (17%) Query: 30 LGDPEL--LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ----LALFKTNKKE 83 L D EL + ++T FS S+I LY F + ++G +++E+FQ LA+ Sbjct: 9 LRDEELEEIKKETGFSHSQITRLYSRFTSLDKG--ENGTLSREDFQRIPELAI------- 59 Query: 84 SLFADRVFDLFDTKHNGILGFEEFARALSVFHP----------NAP-----IDDKIHFSF 128 + DR+ + F + + F F R L+ F P N P +K+HF+F Sbjct: 60 NPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAF 119 Query: 129 QLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 +LYDL + I R E+ Q++ + G+N+ D + I D+T +EAD D I E+ Sbjct: 120 RLYDLDKDEKISRDELLQVLRMMV---GVNISDEQLGSIADRTIQEADQDGDSAISFTEF 176 Query: 189 RSLVLRHPSLLKNMTLQYL 207 VL + + M++++L Sbjct: 177 VK-VLEKVDVEQKMSIRFL 194 >1DGU-A nrPDB Length = 183 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/117 (29%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Query: 82 KESLFADRVFDLFDTK-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIE 140 K + F +R+ +F T L FE+F LSVF A D K H++F+++D G + Sbjct: 57 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 116 Query: 141 RQEVKQMVVATLAES-GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 R+++ ++V E L + ++ +ID EE+D DG I+ E++ ++ R P Sbjct: 117 REDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 173 >2LM5-A nrPDB Length = 214 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/117 (29%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Query: 82 KESLFADRVFDLFDTK-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIE 140 K + F +R+ +F T L FE+F LSVF A D K H++F+++D G + Sbjct: 88 KANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLN 147 Query: 141 RQEVKQMVVATLAES-GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 R+++ ++V E L + ++ +ID EE+D DG I+ E++ ++ R P Sbjct: 148 REDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSP 204 >2JUL-A nrPDB Length = 256 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 87/175 (49%), Gaps = 11/175 (6%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQL--ALFKTNKKESLFADRVFDL 93 L T F+ E+++LY FK GL++++ F+L + F + +A +F+ Sbjct: 82 LQAQTKFTKKELQSLYRGFKNECPT----GLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 FD NG + FE+F LS+ + +K+ ++F LYD+ + G I ++E+ ++ + Sbjct: 138 FDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 Query: 154 ESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + + ED +++ F++ D DG + +E+ + +++ +M L Sbjct: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 >2JU0-A nrPDB Length = 190 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 FA+ +F +FD +NG + FEEF LS +++K+ ++F+LYDL G+I E+ Sbjct: 64 FANHLFTVFDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEML 122 Query: 146 QMVVATLAESG----MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKN 201 +V + G +N + E + K F+ D DG I +E+R PS++ Sbjct: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGA 182 Query: 202 MTL 204 + L Sbjct: 183 LNL 185 >2BEC-A nrPDB Length = 202 Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 26/171 (15%) Query: 30 LGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFAD 88 + D + + R+T FS + + L+ F+ + G +++ + Q + N D Sbjct: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQIGALAVNP----LGD 64 Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHP-------------NAPID---DKIHFSFQLYD 132 R+ + F + + F F R L+ F P P++ +K+H++FQLYD Sbjct: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 Query: 133 LKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 L + G I R E+ Q++ + G+ + + +E+I D+T +EAD DG + Sbjct: 125 LDRDGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAV 172 >2NA0-A nrPDB Length = 205 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 33/120 (27%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Query: 84 SLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 S + +++F+ FD +G + F E+ ALS+ ++ K+ + F+LYD+ G I+R E Sbjct: 53 SQYVEQMFETFDFNKDGYIDFMEYEAALSLVL-KGKVEQKLRWYFKLYDVDGNGCIDRDE 111 Query: 144 VKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 + ++ A A + + E+ D F + D DG++ EE+ V + LL +T Sbjct: 112 LLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLT 171 >2GGZ-A nrPDB Length = 211 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 47/176 (26%), Positives = 85/176 (48%), Gaps = 10/176 (5%) Query: 28 GGLGDPELLARDT-VFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKES 84 G +G+ + +A D E Y F + GL EF+ L L N+K + Sbjct: 1 GHMGNGKSIAGDQKAVPTQETHVWYRTFMMEYPS----GLQTLHEFKTLLGLQGLNQKAN 56 Query: 85 LFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 D+V++ FDT +G + F EF A+++ ++ K+ + F+LYD G I++ E+ Sbjct: 57 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM-QEKMEQKLKWYFKLYDADGNGSIDKNEL 115 Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 M +A A +G + E+ I+ F + D +DG++ EE+ + + + LL+ Sbjct: 116 LDMFMAVQALNGQ--QTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 169 >2R2I-A nrPDB Length = 198 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 34/118 (28%), Positives = 62/118 (52%), Gaps = 2/118 (1%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 + +++F+ FD +G + F E+ ALS+ +D K+ + F+LYD+ G I+R E+ Sbjct: 53 YVEQMFETFDFNKDGYIDFMEYVAALSLV-LKGKVDQKLRWYFKLYDVDGNGCIDRGELL 111 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 ++ A A + N T E+ + F++ D DG++ EE+ V + LL +T Sbjct: 112 NIIKAIRAINRCNEAMTA-EEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILT 168 >2I94-A nrPDB Length = 202 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 9/129 (6%) Query: 26 QSGGLGDP--ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNK 81 +SG L E L +T F+ E+ + Y+ F K + G I ++EFQ + F Sbjct: 5 KSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPS----GRITRQEFQTIYSKFFPEA 60 Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 +A VF FD +G L F+E+ AL + + K+ ++F LYD+ G I + Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSA-GKTNQKLEWAFSLYDVDGNGTISK 119 Query: 142 QEVKQMVVA 150 EV ++V A Sbjct: 120 NEVLEIVTA 128 >2D8N-A nrPDB Length = 207 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 37/119 (31%), Positives = 60/119 (50%), Gaps = 7/119 (5%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L +T FS E+ + Y+ F K G I +++FQ A F + +A VF Sbjct: 22 EELQLNTKFSEEELCSWYQSFLKDCPT----GRITQQQFQSIYAKFFPDTDPKAYAQHVF 77 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FD+ +G L F+E+ AL + + K+ ++F LYD+ G I + EV ++V+A Sbjct: 78 RSFDSNLDGTLDFKEYVIALHM-TTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 >5A2H-A nrPDB Length = 149 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/152 (23%), Positives = 73/152 (48%), Gaps = 16/152 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 +SE + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 10 ISEFKEAFSLFDKDG-----DGCITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 63 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + ++++ +F+++D Q GFI E++ ++ NL + Sbjct: 64 IDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT--------NLGE 115 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + ++ +D+ EAD DG+I+ EE+ +++ Sbjct: 116 KLTDEEVDEMIREADVDGDGQINYEEFVKVMM 147 >5ZOR-A nrPDB Length = 149 Score = 43.5 bits (101), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 38/134 (28%), Positives = 70/134 (52%), Gaps = 14/134 (10%) Query: 65 GLINKEEFQLAL----FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 G I+ EE LA+ F ++ + +R +T NG++ + EF R + Sbjct: 22 GAIDAEEMALAMKGLGFGDLPRDEV--ERTVRSMNTNANGLIEYGEFERMVKSRMAQKDS 79 Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 +++ +FQL+DL ++G I +K+ VA L G N D V++++I EAD D Sbjct: 80 PEEVLKAFQLFDLDKKGKISFANLKE--VAKLL--GENPGDDVLQEMI----AEADEDGD 131 Query: 181 GKIDKEEWRSLVLR 194 G++ EE++S++++ Sbjct: 132 GEVSFEEFKSVMMQ 145 >2L1W-A nrPDB Length = 149 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 29/132 (21%), Positives = 67/132 (50%), Gaps = 11/132 (8%) Query: 64 DGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPID 121 DG I EE + N E D + ++ D NG + F+EF ++ + + Sbjct: 24 DGCITVEELATVIRSLDQNPTEEELQDMISEV-DADGNGTIEFDEFLSLMAKKVKDTDAE 82 Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +++ +F+++D Q G+I E++ +++ NL + + ++ +++ +EAD DG Sbjct: 83 EELKEAFKVFDKDQNGYISASELRHVMI--------NLGEKLTDEEVEQMIKEADLDGDG 134 Query: 182 KIDKEEWRSLVL 193 +++ EE+ +++ Sbjct: 135 QVNYEEFVKMMM 146 >3EK4-A nrPDB Length = 451 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 312 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 365 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 366 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 417 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 418 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 >6O20-F nrPDB Length = 169 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 30 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 83 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 84 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 135 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 136 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 >1JBA-A nrPDB Length = 204 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 30/134 (22%), Positives = 65/134 (48%), Gaps = 10/134 (7%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 N++ + + + +F FDT + + F E+ AL++ ++ K+ ++F++YD + G I Sbjct: 54 NEEATQYVEAMFRAFDTNGDNTIDFLEYVAALNLVL-RGTLEHKLKWTFKIYDKDRNGCI 112 Query: 140 ERQEVKQMV---------VATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRS 190 +RQE+ +V + E+ K E+++D+ F D DG++ E+ Sbjct: 113 DRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVE 172 Query: 191 LVLRHPSLLKNMTL 204 R ++K + + Sbjct: 173 GARRDKWVMKMLQM 186 >3WFN-B nrPDB Length = 182 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 16 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 69 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 70 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 121 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 122 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 >2N6A-A nrPDB Length = 173 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 11 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 64 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 65 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 116 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 117 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 >6HCS-A nrPDB Length = 167 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 70/151 (46%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 10 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 63 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ + NL + Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMT--------NLGE 115 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >4E53-A nrPDB Length = 185 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 17 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 70 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 122 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 123 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >2F2P-A nrPDB Length = 179 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 10 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 63 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 115 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 116 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >5I0I-E nrPDB Length = 145 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 29/131 (22%), Positives = 63/131 (48%), Gaps = 11/131 (8%) Query: 64 DGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPID 121 DG I +E + N E+ D + ++ D NG + F EF ++ + + Sbjct: 23 DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGTIDFPEFLTMMARKMKDTDSE 81 Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++I +F+++D G+I E++ ++ NL + + ++ +D+ EAD DG Sbjct: 82 EEIREAFRVFDKDGNGYISAAELRHVMT--------NLGEKLTDEEVDEMIREADIDGDG 133 Query: 182 KIDKEEWRSLV 192 +++ EE+ ++ Sbjct: 134 QVNYEEFVQMM 144 >4OY4-A nrPDB Length = 415 Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 32/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D +G Sbjct: 17 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGDGT 70 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 122 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 123 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >3U0K-A nrPDB Length = 442 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/151 (21%), Positives = 71/151 (47%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D +G Sbjct: 303 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGDGT 356 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D G+I E++ ++ NL + Sbjct: 357 IDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGE 408 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 409 KLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 >3KF9-A nrPDB Length = 149 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 40/149 (26%), Positives = 75/149 (50%), Gaps = 24/149 (16%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLAL----FKTNKKE--SLFADRVFDLFDTKHN 99 EI ++LF S G I+ +E ++A+ F+ K+E + AD D + Sbjct: 9 EIREAFDLFDTDGS-----GTIDAKELKVAMRALGFEPKKEEIKKMIAD-----IDKDGS 58 Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 G + FEEF + ++ ++I +F+L+D + G I + +K++ E G N+ Sbjct: 59 GTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVA----KELGENM 114 Query: 160 KDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 D ++++ID EAD DG++++EE+ Sbjct: 115 TDEELQEMID----EADRDGDGEVNEEEF 139 >2LMV-A nrPDB Length = 148 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/98 (25%), Positives = 50/98 (51%), Gaps = 8/98 (8%) Query: 95 DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 + +NG L F EF ++ ++++ +F+++D GFI E++ +++ Sbjct: 56 ENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMI----- 110 Query: 155 SGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + V ++ ID+ EAD DG I+ EE+ ++ Sbjct: 111 ---NLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMI 145 >1GGZ-A nrPDB Length = 148 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/152 (23%), Positives = 70/152 (46%), Gaps = 17/152 (11%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 V+E + + LF K DG I E + N E+ D + ++ D NG Sbjct: 9 VTEFKEAFSLFDKDG-----DGCITTRELGTVMRSLGQNPTEAELRDMMSEI-DRDGNGT 62 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + +++I +F+++D GF+ E++ ++ L + Sbjct: 63 VDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMT--------RLGE 114 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEW-RSLV 192 + ++ +D+ ADT DG+++ EE+ R LV Sbjct: 115 KLSDEEVDEMIRAADTDGDGQVNYEEFVRVLV 146 >1CLM-A nrPDB Length = 148 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 34/152 (22%), Positives = 69/152 (45%), Gaps = 16/152 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 9 IAEFKEAFALFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 62 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ ++++ +F+++D G I E++ ++ NL + Sbjct: 63 IDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMT--------NLGE 114 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + +D +D+ EAD DG I+ EE+ +++ Sbjct: 115 KLTDDEVDEMIREADIDGDGHINYEEFVRMMV 146 >5PAL-A nrPDB Length = 109 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Query: 106 EFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIE 165 ++ R + D ++ F++ D Q GFIE +E+K V+ + G +L DT + Sbjct: 25 DYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKG-VLKGFSAHGRDLNDTETK 83 Query: 166 DIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ D+ HDGKI +E+ +V + Sbjct: 84 ALL----AAGDSDHDGKIGADEFAKMVAQ 108 >5ZGM-A nrPDB Length = 110 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F++ D Q GFIE +E+K V+ + G +L DT + ++ D+ HDGKI +E Sbjct: 48 FEILDKDQSGFIEEEELKS-VLKGFSAHGRDLSDTETKALL----AAGDSDHDGKIGADE 102 Query: 188 WRSLVLR 194 + +V + Sbjct: 103 FAKMVAQ 109 >2Q4U-A nrPDB Length = 272 Score = 36.2 bits (82), Expect = 0.011, Method: Compositional matrix adjust. Identities = 39/171 (22%), Positives = 71/171 (41%), Gaps = 25/171 (14%) Query: 63 DDGLINKEE----FQLALFKTNKKESLFADRV-------FDLFDTKHNGILGFEEFARA- 110 D+G I +E F+ L K K+ + +RV +D +G L EE A Sbjct: 24 DNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEELANMI 83 Query: 111 -------LSVFHPNAPIDDKIHFS--FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 L +F AP+D+ + F ++ YD G+I E+K + + + Sbjct: 84 LPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPP 143 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDITT 212 +++ D + D DG++D + + R +L +N LQ+ D ++ Sbjct: 144 NKLDEYTDAMMKIFDKNKDGRLDLND----LARILALQENFLLQFKMDASS 190 >1S6I-A nrPDB Length = 188 Score = 36.2 bits (82), Expect = 0.011, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 18/159 (11%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK--ESLFADRVFDLFDTKHN 99 S EI L ELFK I + + G I +E + L + + ES D + D D + Sbjct: 4 LSEEEIGGLKELFKMIDTD--NSGTITFDELKDGLKRVGSELMESEIKD-LMDAADIDKS 60 Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 G + + EF A +V ++ + +F +D G+I E++Q Sbjct: 61 GTIDYGEFI-AATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQAC----------- 108 Query: 160 KDTVIEDI-IDKTFEEADTKHDGKIDKEEWRSLVLRHPS 197 KD ++DI ID +E D +DG+ID E+ +++ + Sbjct: 109 KDFGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRKRKG 147 >1DTL-A nrPDB Length = 161 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 13/104 (12%) Query: 89 RVFDLFDTKHNGILGFEEF----ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 + D D +G + F+EF R++ ++++ F+++D G+I+ +E+ Sbjct: 59 EMIDEVDEDGSGTVDFDEFLVMMVRSMKD-DSKGKSEEELSDLFRMFDKNADGYIDLEEL 117 Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 K M+ AT +T+ ED I++ ++ D +DG+ID +E+ Sbjct: 118 KIMLQAT--------GETITEDDIEELMKDGDKNNDGRIDYDEF 153 >2E6W-A nrPDB Length = 100 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 20/91 (21%), Positives = 47/91 (51%), Gaps = 4/91 (4%) Query: 118 APIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI----IDKTFE 173 + +K+ ++F LYD+ + G+I ++E+ ++ + G + + ED +++ FE Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 174 EADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 + D DG + EE+ + +++ +M L Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIMSSMQL 95 >1OZS-A nrPDB Length = 73 Score = 35.4 bits (80), Expect = 0.020, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 37/61 (60%), Gaps = 8/61 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+++D G+I+ +E+K M+ AT +T+ ED I++ ++ D +DG+ID +E Sbjct: 13 FRMFDKNADGYIDLEELKIMLQAT--------GETITEDDIEELMKDGDKNNDGRIDYDE 64 Query: 188 W 188 + Sbjct: 65 F 65 >6IIE-A nrPDB Length = 93 Score = 34.7 bits (78), Expect = 0.038, Method: Compositional matrix adjust. Identities = 16/69 (23%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATL-AESGMNLKDTVIEDIIDKTFEEADTKH 179 +DK+ F+F+LYD + G ++ EV ++++ + ++ + + I+ + +E D Sbjct: 8 EDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDG 67 Query: 180 DGKIDKEEW 188 G + + EW Sbjct: 68 SGSVSQAEW 76 >4JWQ-A nrPDB Length = 199 Score = 34.3 bits (77), Expect = 0.041, Method: Compositional matrix adjust. Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Query: 65 GLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF-ARALSVFHPNAPIDDK 123 G I K + + L + K D + D D+ +G + + EF A AL H + + Sbjct: 73 GNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFLAAALDRKHLSKKL--- 129 Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 I+ +F+++D+ G I E+ ++ + + KD + + K +E D +DGKI Sbjct: 130 IYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDV---NQVKKMIQEVDKNNDGKI 186 Query: 184 DKEEW 188 D E+ Sbjct: 187 DFYEF 191 >2KN2-A nrPDB Length = 92 Score = 33.9 bits (76), Expect = 0.056, Method: Compositional matrix adjust. Identities = 16/79 (20%), Positives = 46/79 (58%), Gaps = 8/79 (10%) Query: 115 HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEE 174 H + ++++ +F+++D Q G+I E++ +++ NL + + ++ +++ +E Sbjct: 2 HMDTDAEEELKEAFKVFDKDQNGYISASELRHVMI--------NLGEKLTDEEVEQMIKE 53 Query: 175 ADTKHDGKIDKEEWRSLVL 193 AD DG+++ EE+ +++ Sbjct: 54 ADLDGDGQVNYEEFVKMMM 72 >5UKG-A nrPDB Length = 419 Score = 33.9 bits (76), Expect = 0.066, Method: Compositional matrix adjust. Identities = 30/151 (19%), Positives = 68/151 (45%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D +G Sbjct: 280 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGDGT 333 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 F EF ++ +++I +F+++D G+I E++ ++ +L + Sbjct: 334 FDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMT--------DLGE 385 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ AD DG+++ EE+ ++ Sbjct: 386 KLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 >2RO9-A nrPDB Length = 69 Score = 33.5 bits (75), Expect = 0.067, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 38/67 (56%), Gaps = 8/67 (11%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +F+++D Q GFI E++ ++ NL + + ++ +D+ EAD DG+I+ E Sbjct: 9 AFRVFDKDQNGFISAAELRHVMT--------NLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 187 EWRSLVL 193 E+ +++ Sbjct: 61 EFVKVMM 67 >2AAO-A nrPDB Length = 166 Score = 33.1 bits (74), Expect = 0.091, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 71/156 (45%), Gaps = 18/156 (11%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFK--TNKKESLFADRVFDLFDTKHN 99 S EI L E+F I + G I EE + L + N KES D + D ++ Sbjct: 21 LSEEEIAGLKEMFNMIDAD--KSGQITFEELKAGLKRVGANLKESEILD-LMQAADVDNS 77 Query: 100 GILGFEEFARALSVFHPNA-PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 G + ++EF A H N +D + +F +D G+I E++Q A Sbjct: 78 GTIDYKEFIAA--TLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQ------ACEEFG 129 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++D IE+++ + D +DG+ID E+ +++ + Sbjct: 130 VEDVRIEELM----RDVDQDNDGRIDYNEFVAMMQK 161 >3K21-A nrPDB Length = 191 Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust. Identities = 30/129 (23%), Positives = 59/129 (45%), Gaps = 7/129 (5%) Query: 65 GLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF-ARALSVFHPNAPIDDK 123 G I KE+ + L K K D + D D+ +G + + EF A AL + + Sbjct: 67 GYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFIAAALDRKQLSKKL--- 123 Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 I+ +F+++D+ G I E+ ++ + + +D + + + + D +DGKI Sbjct: 124 IYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQRDV---NRVKRMIRDVDKNNDGKI 180 Query: 184 DKEEWRSLV 192 D E+ ++ Sbjct: 181 DFHEFSEMM 189 >2G9B-A nrPDB Length = 263 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +++ YD GFIE +E+K + L ++ + DT + + D + D+ +DGK++ Sbjct: 108 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 167 Query: 187 EW-RSLVLRHPSLLK 200 E R L ++ LLK Sbjct: 168 EMARLLPVQENFLLK 182 Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust. Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 23/101 (22%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSV-------FHPNAPIDDKIHFSFQLYDLKQQGF 138 + D + LFD+ ++G L E AR L V F + + +F+LYD G+ Sbjct: 148 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 207 Query: 139 IERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 I+ E+ D +++D+ +K +E D + Sbjct: 208 IDENEL----------------DALLKDLCEKNKQELDINN 232 >4I2Y-A nrPDB Length = 421 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 30/151 (19%), Positives = 69/151 (45%), Gaps = 16/151 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D +G Sbjct: 282 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGDGT 335 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 F EF ++ + +++I +F+++D G+I E++ ++ +L + Sbjct: 336 FDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMT--------DLGE 387 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ AD DG+++ EE+ ++ Sbjct: 388 KLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 >2WCE-A nrPDB Length = 95 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 5/67 (7%) Query: 128 FQLYDLKQQGF--IERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDK 185 F Y +++ F + + E+KQ++ LA + N+KD +ID+ F+ D D ++D Sbjct: 18 FHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKA---VIDEIFQGLDANQDEQVDF 74 Query: 186 EEWRSLV 192 +E+ S+V Sbjct: 75 QEFISMV 81 >1TOP-A nrPDB Length = 162 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 63/121 (52%), Gaps = 15/121 (12%) Query: 76 LFKTNKKESLFADRVFDLFDTKHNGILGFEEF----ARALSVFHPNAPIDDKIHFSFQLY 131 L + KE L D + + D +G + FEEF R + ++++ F+++ Sbjct: 49 LGQNPTKEEL--DAIIEEVDEDGSGTIDFEEFLVMMVRQMKE-DAKGKSEEELANCFRIF 105 Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 D GFI+ +E+ +++ AT G ++ + IED++ +++D +DG+ID +E+ + Sbjct: 106 DKNADGFIDIEELGEILRAT----GEHVTEEDIEDLM----KDSDKNNDGRIDFDEFLKM 157 Query: 192 V 192 + Sbjct: 158 M 158 >2LUC-A nrPDB Length = 105 Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Query: 47 IEALYELFKKISSAVIDDGLINKEEF------QLALFKTNKKESLFADRVFDLFDTKHNG 100 IE+L +F+K + + ++K EF +LA F N+K+ DR+ DT +G Sbjct: 14 IESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDG 73 Query: 101 ILGFEEF 107 L F EF Sbjct: 74 QLDFSEF 80 >4ZCV-A nrPDB Length = 165 Score = 32.3 bits (72), Expect = 0.19, Method: Compositional matrix adjust. Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 18/149 (12%) Query: 48 EALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF 107 E L++ + V+D G + + L + E +++F D +G L FEEF Sbjct: 16 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE----EKIFTTGDVNKDGKLDFEEF 71 Query: 108 ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 + L K+ +F+ D G IE E +V +L G+ + + E I Sbjct: 72 MKYLKDHEK------KMKLAFKSLDKNNDGKIEASE----IVQSLQTLGLTISEQQAELI 121 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + + D +D EWR L +P Sbjct: 122 L----QSIDVDGTMTVDWNEWRDYFLFNP 146 >1QLS-A nrPDB Length = 99 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 6/67 (8%) Query: 47 IEALYELFKKISSAVIDDGLINKEEF------QLALFKTNKKESLFADRVFDLFDTKHNG 100 IE+L +F+K + ++ I+K EF +LA F N+K+ DR+ D +G Sbjct: 12 IESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDG 71 Query: 101 ILGFEEF 107 L F+EF Sbjct: 72 QLDFQEF 78 >5D43-A nrPDB Length = 178 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 42/169 (24%), Positives = 80/169 (47%), Gaps = 25/169 (14%) Query: 24 YKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL----FKT 79 YK+ G PEL T E+ ++LF S G I+ +E ++A+ F+ Sbjct: 15 YKRKVG-PKPEL----TEDQKQEVREAFDLFDSDGS-----GTIDVKELKVAMRALGFEP 64 Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 K+E ++ D + G + F +F ++ ++I +F+L+D + G I Sbjct: 65 RKEE---MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 Query: 140 ERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 + +K++ E G +L D ++++ID EAD DG++++EE+ Sbjct: 122 SFKNLKRVA----NELGESLTDEELQEMID----EADRDGDGEVNEEEF 162 >1IYJ-B nrPDB Length = 817 Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust. Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 7/78 (8%) Query: 39 DTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFD--- 95 D+V S + LY +S A I N E FQ A+ KE+L A + F L D Sbjct: 125 DSVPSACSPKQLY--MYGVSKACISVNSKNAEYFQFAIEDHFGKEALCAGKGFRLADGGW 182 Query: 96 --TKHNGILGFEEFARAL 111 +G G EEF RAL Sbjct: 183 LIPSDDGKAGKEEFYRAL 200 >5E37-A nrPDB Length = 356 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 42/74 (56%), Gaps = 5/74 (6%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESG---MNLKDTVIEDIIDKTFEEADTK 178 +++ F++ D+ G I+R+E++ ++ + ESG M + + ED +++ E+ D Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESM--ESGEVYMMSQHWLPEDELERCMEQYDVN 86 Query: 179 HDGKIDKEEWRSLV 192 DG I EE++ ++ Sbjct: 87 KDGVISFEEFKQII 100 Score = 27.7 bits (60), Expect = 3.8, Method: Compositional matrix adjust. Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 18/135 (13%) Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPI--------DDKIHFSFQLYDLKQQGFI 139 +R F + D NG + EE L +D++ + YD+ + G I Sbjct: 32 ERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKDGVI 91 Query: 140 ERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 +E KQ++ G+ L+ T+ E + F+ D +G I E L SL Sbjct: 92 SFEEFKQIIY-----DGLLLEGTLAE--YESAFKAVDKSGNGTIGATELSKL---FASLG 141 Query: 200 KNMTLQYLKDITTTF 214 ++L+ L D+ + Sbjct: 142 NPVSLEKLVDLMQMY 156 >4N5X-A nrPDB Length = 199 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 18/149 (12%) Query: 48 EALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF 107 E L++ + V+D G + + L + E +++F D +G L FEEF Sbjct: 25 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE----EKIFTTGDVNKDGKLDFEEF 80 Query: 108 ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 + L K+ +F+ D G IE E +V +L G+ + + E I Sbjct: 81 MKYLKDHEK------KMKLAFKSLDKNNDGKIEASE----IVQSLQTLGLTISEQQAELI 130 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + + D +D EWR L +P Sbjct: 131 L----QSIDVDGTMTVDWNEWRDYFLFNP 155 >2KQY-A nrPDB Length = 108 Score = 32.0 bits (71), Expect = 0.22, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 7/72 (9%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA-DTKHD 180 D+I F + D + GFIE +E+ Q+ + + S V+ K F A DT D Sbjct: 41 DQIKKVFGILDQDKSGFIEEEEL-QLFLKNFSSSAR-----VLTSAETKAFLAAGDTDGD 94 Query: 181 GKIDKEEWRSLV 192 GKI EE++SLV Sbjct: 95 GKIGVEEFQSLV 106 >3QRX-A nrPDB Length = 169 Score = 32.0 bits (71), Expect = 0.22, Method: Compositional matrix adjust. Identities = 36/147 (24%), Positives = 71/147 (48%), Gaps = 20/147 (13%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLAL----FKTNKKESLFADRVFDLFDTKHNGI 101 EI ++LF S G I+ +E ++A+ F+ K+E ++ D +G Sbjct: 29 EIREAFDLFDTDGS-----GTIDAKELKVAMRALGFEPKKEE---IKKMISEIDKDGSGT 80 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + FEEF ++ ++I +F+L+D G I ++++++ E G NL + Sbjct: 81 IDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVA----KELGENLTE 136 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEW 188 ++++I EAD D +ID++E+ Sbjct: 137 EELQEMI----AEADRNDDNEIDEDEF 159 >3PAT-A nrPDB Length = 110 Score = 32.0 bits (71), Expect = 0.23, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ D GFIE +E+K V+ + A G +L D + + + AD DGKI +E Sbjct: 48 FKAIDADASGFIEEEELK-FVLKSFAADGRDLTDAETKAFL----KAADKDGDGKIGIDE 102 Query: 188 WRSLV 192 + +LV Sbjct: 103 FETLV 107 >2ROB-A nrPDB Length = 70 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 15/67 (22%), Positives = 40/67 (59%), Gaps = 8/67 (11%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +F+++D Q G+I E++ +++ NL + + ++ +++ +EAD DG+++ E Sbjct: 9 AFKVFDKDQNGYISASELRHVMI--------NLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 187 EWRSLVL 193 E+ +++ Sbjct: 61 EFVKMMM 67 >4WPX-A nrPDB Length = 177 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 56/152 (36%) Query: 90 VFDLFDTKHNGILGFEEFA---RALS------------VFHPNAPID------------- 121 F+LFD+ +G+L +EEF RAL V H P + Sbjct: 31 AFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWPHDQECPPVYRQ 90 Query: 122 --------------------DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 D++ +F+L+D+ +G I +++++ + G N+ D Sbjct: 91 FNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVC----QQVGNNIPD 146 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 I+ +I EE D+ G +D++E+ L++ Sbjct: 147 ADIQAMI----EEFDSNGKGGVDEDEFLRLMM 174 >6I8Y-A nrPDB Length = 222 Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 20/102 (19%) Query: 122 DKIHFSFQLYDLKQQGF-------------IERQEVKQMVVATLAESGMNLKDTVIEDII 168 D++ + LY +K GF + EV VAT S +L DT+I + Sbjct: 31 DQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAV 90 Query: 169 DKTFEEADTKHDGKIDKEEWRSLVL-RHPSLLKNMTLQYLKD 209 + FE D K+EWR +VL R P + + Y KD Sbjct: 91 EHMFETEDGS------KDEWRGMVLARAPVMNTWFYITYEKD 126 >2TN4-A nrPDB Length = 159 Score = 31.6 bits (70), Expect = 0.30, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 15/121 (12%) Query: 76 LFKTNKKESLFADRVFDLFDTKHNGILGFEEF----ARALSVFHPNAPIDDKIHFSFQLY 131 L +T KE L D + + D +G + FEEF R + ++++ F+++ Sbjct: 46 LGQTPTKEEL--DAIIEEVDEDGSGTIDFEEFLVMMVRQMKE-DAKGKSEEELAELFRIF 102 Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 D G+I+ +E+ ++ A SG ++ D IE ++ ++ D +DG+ID +E+ + Sbjct: 103 DRNADGYIDAEELAEIFRA----SGEHVTDEEIESLM----KDGDKNNDGRIDFDEFLKM 154 Query: 192 V 192 + Sbjct: 155 M 155 >2NS2-A nrPDB Length = 242 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 20/102 (19%) Query: 122 DKIHFSFQLYDLKQQGF-------------IERQEVKQMVVATLAESGMNLKDTVIEDII 168 D++ + LY +K GF + EV VAT S +L DT+I + Sbjct: 58 DQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAV 117 Query: 169 DKTFEEADTKHDGKIDKEEWRSLVL-RHPSLLKNMTLQYLKD 209 + FE D K+EWR +VL R P + + Y KD Sbjct: 118 EHMFETEDGS------KDEWRGMVLARAPVMNTWFYITYEKD 153 >2GGM-A nrPDB Length = 172 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 69/138 (50%), Gaps = 16/138 (11%) Query: 65 GLINKEEFQLAL----FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 G I+ +E ++A+ F+ K+E ++ D + G + F +F ++ Sbjct: 46 GTIDVKELKVAMRALGFEPKKEE---IKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDT 102 Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 ++I +F+L+D + G I + +K++ E G NL D ++++ID EAD D Sbjct: 103 KEEILKAFKLFDDDETGKISFKNLKRVA----KELGENLTDEELQEMID----EADRDGD 154 Query: 181 GKIDKEEWRSLVLRHPSL 198 G++ ++E+ +++ SL Sbjct: 155 GEVSEQEFLR-IMKKTSL 171 >5MWC-D nrPDB Length = 311 Score = 31.2 bits (69), Expect = 0.36, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 8/74 (10%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 P ++++ F+ +D GFI+R+E ++ T G L D ED D+ F ++DT Sbjct: 148 PSEEELSECFRTFDKDGDGFIDREEFGGIIRLT----GEQLTD---EDP-DEIFGDSDTD 199 Query: 179 HDGKIDKEEWRSLV 192 +G+ID +E+ +V Sbjct: 200 KNGRIDFDEFLKMV 213 Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%) Query: 25 KQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-E 83 K +G D ++A V E L E F+ DG I++EEF + T ++ Sbjct: 128 KGTGFPADGPVMANSLTAMVPSEEELSECFRTFDKD--GDGFIDREEFGGIIRLTGEQLT 185 Query: 84 SLFADRVFDLFDTKHNGILGFEEFARAL 111 D +F DT NG + F+EF + + Sbjct: 186 DEDPDEIFGDSDTDKNGRIDFDEFLKMV 213 >1JC2-A nrPDB Length = 76 Score = 30.8 bits (68), Expect = 0.44, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 39/65 (60%), Gaps = 8/65 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+++D GFI+ +E+ +++ AT + VIE+ I+ +++D +DG+ID +E Sbjct: 16 FRIFDKNADGFIDIEELGEILRAT--------GEHVIEEDIEDLMKDSDKNNDGRIDFDE 67 Query: 188 WRSLV 192 + ++ Sbjct: 68 FLKMM 72 >2NCO-A nrPDB Length = 102 Score = 30.8 bits (68), Expect = 0.45, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ YD G ++ E+ ++ T AE GM+ ED+ + ADT DG + EE Sbjct: 21 FKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDV-KIWLQMADTNSDGSVSLEE 79 Query: 188 WRSLVLR 194 + L+++ Sbjct: 80 YEDLIIK 86 >2M97-A nrPDB Length = 69 Score = 30.8 bits (68), Expect = 0.45, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 8/65 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+++D GFI+R+E ++ T G L D ED+ D+ F ++DT +G+ID +E Sbjct: 9 FRIFDKDGNGFIDREEFGDIIRLT----GEQLTD---EDV-DEIFGDSDTDKNGRIDFDE 60 Query: 188 WRSLV 192 + ++ Sbjct: 61 FLKMM 65 >2OBH-A nrPDB Length = 143 Score = 30.8 bits (68), Expect = 0.49, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 64/128 (50%), Gaps = 15/128 (11%) Query: 65 GLINKEEFQLAL----FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 G I+ +E ++A+ F+ K+E ++ D + G + F +F ++ Sbjct: 21 GTIDVKELKVAMRALGFEPKKEE---IKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDT 77 Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 ++I +F+L+D + G I + +K++ E G NL D ++++ID EAD D Sbjct: 78 KEEILKAFKLFDDDETGKISFKNLKRVA----KELGENLTDEELQEMID----EADRDGD 129 Query: 181 GKIDKEEW 188 G++ ++E+ Sbjct: 130 GEVSEQEF 137 >4RGJ-A nrPDB Length = 520 Score = 30.4 bits (67), Expect = 0.61, Method: Compositional matrix adjust. Identities = 25/108 (23%), Positives = 52/108 (48%), Gaps = 11/108 (10%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 D++ + D NG + + EF +S+ +++ +F+L+D G I E+ Q Sbjct: 420 VDQILNSIDLDQNGYIEYSEFL-TVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQ 478 Query: 147 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + L++ TV++ E D +DG+ID +E+R ++++ Sbjct: 479 LF--GLSDVSSECWKTVLK--------EVDQNNDGEIDFKEFRDMLVK 516 >2IO3-A nrPDB Length = 232 Score = 30.4 bits (67), Expect = 0.68, Method: Compositional matrix adjust. Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 18/119 (15%) Query: 76 LFKTNKKESLFADRVFDLF---DTKHNGILGFEEFARALSVFHPN---APIDDKIHFSFQ 129 L + NKK+ A VF F K G + + + +++F PI K+H+S Sbjct: 66 LVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLV 125 Query: 130 LYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 + DL+++ + ++ + G + + +++ + D E+ TK + ++ EW Sbjct: 126 VIDLRKKCL--------KYLDSMGQKGHRICEILLQYLQD----ESKTKRNSDLNLLEW 172 >1NSH-A nrPDB Length = 101 Score = 30.4 bits (67), Expect = 0.68, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%) Query: 47 IEALYELFKKISSAVIDDGLINKEEF------QLALFKTNKKESLFADRVFDLFDTKHNG 100 IE+L +F+K + ++K EF +LA F N+K+ DR+ D +G Sbjct: 10 IESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDG 69 Query: 101 ILGFEEF 107 L F+EF Sbjct: 70 QLDFQEF 76 >2BL0-C nrPDB Length = 142 Score = 30.0 bits (66), Expect = 0.76, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 8/69 (11%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +F+L+D ++ GFI K+ + L + G+ ++ ++ F EAD +GKI Sbjct: 11 AFELFDSERTGFI----TKEGLQTVLKQFGVRVEPAAFNEM----FNEADATGNGKIQFP 62 Query: 187 EWRSLVLRH 195 E+ S++ R Sbjct: 63 EFLSMMGRR 71 >1FW4-A nrPDB Length = 71 Score = 30.0 bits (66), Expect = 0.86, Method: Compositional matrix adjust. Identities = 16/72 (22%), Positives = 40/72 (55%), Gaps = 8/72 (11%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 +++I +F+++D G+I E++ ++ NL + + ++ +D+ EAD D Sbjct: 5 EEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGEKLTDEEVDEMIREADIDGD 56 Query: 181 GKIDKEEWRSLV 192 G+++ EE+ ++ Sbjct: 57 GQVNYEEFVQMM 68 >2M5E-A nrPDB Length = 73 Score = 30.0 bits (66), Expect = 0.87, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 8/67 (11%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +F+++D G I E++ ++ NL + + +D +D+ EAD DG I+ E Sbjct: 13 AFKVFDRDGNGLISAAELRHVMT--------NLGEKLTDDEVDEMIREADIDGDGHINYE 64 Query: 187 EWRSLVL 193 E+ +++ Sbjct: 65 EFVRMMV 71 >4YZB-A nrPDB Length = 491 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/107 (20%), Positives = 47/107 (43%), Gaps = 11/107 (10%) Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 ++V D D NG + + EF +++ ++ +F ++D G I E+ + Sbjct: 389 EQVLDAVDFDKNGFIEYSEFV-TVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATI 447 Query: 148 VVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + +S + + E D +DG++D EE+R ++L+ Sbjct: 448 FGVSEVDS----------ETWRRVLAEVDRNNDGEVDFEEFRQMLLK 484 >2M29-A nrPDB Length = 171 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 26/110 (23%), Positives = 46/110 (41%), Gaps = 7/110 (6%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 F+ FDT +G +G+ E + P + ++ Q ++ GF++ +E +++ Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMRTLG-YMPTEMELLEVSQHVKMRMGGFVDFEEFVELIS 91 Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 L E ++ I F E D DG+I E R P+LL Sbjct: 92 PKLREETAHMLGVRELRI---AFREFDKDRDGRITVAELRQAA---PALL 135 >1JF0-A nrPDB Length = 195 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Query: 64 DGLINKEEFQLALFKTNKKESL--FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPID 121 +G N LA + N+ + + D VFD+FD +G + +E+ +A +P + Sbjct: 90 EGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEW-KAYGRISGISPSE 148 Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQ 146 + +FQ DL G ++ E+ + Sbjct: 149 EDCEKTFQHCDLDNSGELDVDEMTR 173 >5ZH6-A nrPDB Length = 107 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F + D + GFIE E+K + + + + L +T + D+ HDGKI +E Sbjct: 46 FDILDQDRSGFIEVDELK-LFLQNFSATARELDETETNAFL----AAGDSDHDGKIGVDE 100 Query: 188 WRSLV 192 ++++V Sbjct: 101 FKAMV 105 >1A75-A nrPDB Length = 108 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 7/72 (9%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA-DTKHD 180 D I +F D + GFIE E+K + A + + D K F +A D+ D Sbjct: 41 DDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGA------RALTDAETKAFLKAGDSDGD 94 Query: 181 GKIDKEEWRSLV 192 G I EEW +LV Sbjct: 95 GAIGVEEWVALV 106 >2Z23-A nrPDB Length = 517 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 6/85 (7%) Query: 145 KQMVVATLAESGMNLK-DTVIEDIIDKTFEEADTKHDGKID--KEEWRSLVLRHPSLLKN 201 K++ +A + NL D +E+ KTF DT+H G D + W PS N Sbjct: 372 KKLAIAAASIWKKNLGVDVKLENQEWKTF--LDTRHQGTYDVARAAW-CADYNEPSSFLN 428 Query: 202 MTLQYLKDITTTFPSFVFHSQVEDT 226 M L + TT + S VF +EDT Sbjct: 429 MMLSNSSNNTTHYKSSVFDKLIEDT 453 >2KYF-A nrPDB Length = 108 Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTF-EEADTKHDGKIDKE 186 F++ D Q GFIE E+K + ESG V+ KTF AD DGKI E Sbjct: 47 FRILDNDQSGFIEEDELKYFL--QRFESGAR----VLTASETKTFLAAADHDGDGKIGAE 100 Query: 187 EWRSLV 192 E++ +V Sbjct: 101 EFQEMV 106 >1M39-A nrPDB Length = 89 Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 50/97 (51%), Gaps = 9/97 (9%) Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F +F ++ ++I +F+L+D + G I + +K++ E G NL D Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVA----KELGENLTD 56 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSL 198 ++++ID EAD DG++ ++E+ +++ SL Sbjct: 57 EELQEMID----EADRDGDGEVSEQEFLR-IMKKTSL 88 >1BU3-A nrPDB Length = 109 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 5/71 (7%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 D I +F + D + GFIE E+K + + + L D + + + D+ DG Sbjct: 42 DDIKKAFFVIDQDKSGFIEEDELK-LFLQVFSAGARALTDAETKAFL----KAGDSDGDG 96 Query: 182 KIDKEEWRSLV 192 I +EW +LV Sbjct: 97 AIGVDEWAALV 107 >2KZ2-A nrPDB Length = 94 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 16/72 (22%), Positives = 39/72 (54%), Gaps = 8/72 (11%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 +++I +F++ D G+I E++ ++ NL + + ++ +D+ EAD D Sbjct: 28 EEEIREAFRVEDKDGNGYISAAELRHVMT--------NLGEKLTDEEVDEMIREADIDGD 79 Query: 181 GKIDKEEWRSLV 192 G+++ EE+ ++ Sbjct: 80 GQVNYEEFVQMM 91 >5DJ4-A nrPDB Length = 480 Score = 28.1 bits (61), Expect = 2.9, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 10/76 (13%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFD-TKHNGI 101 S ++EAL E +++ +++ D ++EE + + F+ K ESL D+ + + H + Sbjct: 254 SARDVEALMERMQQLQESLLRDEGTSQEEME-SRFELEKSESLLVTPSADILEPSPHPDM 312 Query: 102 L--------GFEEFAR 109 L G+E+F R Sbjct: 313 LCFVEDPTFGYEDFTR 328 >5CPV-A nrPDB Length = 109 Score = 28.1 bits (61), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 7/72 (9%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA-DTKHD 180 D + +F + D + GFIE E+K + A++ + D KTF +A D+ D Sbjct: 42 DDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADA------RALTDGETKTFLKAGDSDGD 95 Query: 181 GKIDKEEWRSLV 192 GKI +E+ +LV Sbjct: 96 GKIGVDEFTALV 107 >3AAJ-A nrPDB Length = 167 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 22/129 (17%) Query: 50 LYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLF----ADRVFDLFDTKHNGILGFE 105 L+ +F+++ G+I+ E Q AL +N + F + +FD ++ + F Sbjct: 6 LWNVFQRVDKD--RSGVISDTELQQAL--SNGTWTPFNPVTVRSIISMFDRENKAGVNFS 61 Query: 106 EFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIE 165 EF + F+ YD G I++ E+KQ A SG L D Sbjct: 62 EFTGVWKYITDWQNV-------FRTYDRDNSGMIDKNELKQ------ALSGYRLSDQ-FH 107 Query: 166 DIIDKTFEE 174 DI+ + F+ Sbjct: 108 DILIRKFDR 116 >1TIZ-A nrPDB Length = 67 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQG 137 A RVF+ FD +G L +EF F P +D + F F+ D+ G Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKF-FEEIDVDGNG 52 >1Q80-A nrPDB Length = 174 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 9/116 (7%) Query: 9 KHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSV-------SEIEALYELFKKISSAV 61 K L S+ G +D L +GG G E +++ + S +E LF + + Sbjct: 47 KVLMDSLTGVWDNFLTAVAGGKGIDETTFINSMKEMVKNPEAKSVVEGPLPLFFR-AVDT 105 Query: 62 IDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPN 117 +D I+++E+ + F + A FD DT ++G+L EEF A S F N Sbjct: 106 NEDNNISRDEYGI-FFGMLGLDKTMAPASFDAIDTNNDGLLSLEEFVIAGSDFFMN 160 >2PMY-A nrPDB Length = 91 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 17/91 (18%) Query: 22 DLYKQSGGLGDPELLAR-DTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTN 80 +LY Q G GD E LAR +VF+ + G + +EEF+ AL Sbjct: 13 NLYFQ-GADGDGEELARLRSVFAACDAN--------------RSGRLEREEFR-ALCTEL 56 Query: 81 KKESLFADRVFDLFDTKHNGILGFEEFARAL 111 + A+ VF D +G + F+EFAR Sbjct: 57 RVRPADAEAVFQRLDADRDGAITFQEFARGF 87 >5JN2-A nrPDB Length = 525 Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust. Identities = 21/107 (19%), Positives = 48/107 (44%), Gaps = 11/107 (10%) Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 D+V D D NG + + EF +++ +++ +F+++D G I E+ + Sbjct: 426 DQVLDAVDFDKNGYIEYSEFV-TVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATI 484 Query: 148 VVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + +S + E D +DG++D +E++ ++L+ Sbjct: 485 FGVSDVDS----------ETWKSVLSEVDKNNDGEVDFDEFQQMLLK 521 >3KPX-A nrPDB Length = 198 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 13/110 (11%) Query: 48 EALYELFKKIS---------SAVIDDGLINKEEFQLALFKTNKKESL--FADRVFDLFDT 96 EA+ FKKI A ++ G + L L+ NKK + + + VFD+FD Sbjct: 69 EAVEAFFKKIGLDYGKEVEFPAFVN-GWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDK 127 Query: 97 KHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 +G + +E+ + P D+ +F+ DL G ++ E+ + Sbjct: 128 DGSGSISLDEW-KTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 >2JXC-A nrPDB Length = 100 Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 10/52 (19%) Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 GF+ +VK ++ +N K V DI+ + +E +D HDG +D++E Sbjct: 28 NGFLSGDKVKPVL--------LNSKLPV--DILGRVWELSDIDHDGMLDRDE 69 >2LV7-A nrPDB Length = 100 Score = 27.3 bits (59), Expect = 4.9, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 8/71 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++I +F+++D GFI +QE+ + G + +E II + D DG Sbjct: 36 EEIREAFKVFDRDGNGFISKQELG----TAMRSLGYMPNEVELEVIIQRL----DMDGDG 87 Query: 182 KIDKEEWRSLV 192 ++D EE+ +L+ Sbjct: 88 QVDFEEFVTLL 98 >5XND-A nrPDB Length = 114 Score = 27.3 bits (59), Expect = 5.0, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 11/74 (14%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDT--VIEDIIDKTFEEA-DTK 178 D++ +F + D + GFIE +E+K + N K + D K F +A D+ Sbjct: 47 DEVKKAFAIIDQDKSGFIEEEELKLFL--------QNFKAGARALSDAETKAFLKAGDSD 98 Query: 179 HDGKIDKEEWRSLV 192 DGKI +E+ +++ Sbjct: 99 GDGKIGIDEFAAMI 112 >5LUG-A nrPDB Length = 222 Score = 27.3 bits (59), Expect = 5.0, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 7/62 (11%) Query: 149 VATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNM-TLQYL 207 VA+ S NL +T+I ++ FE +H K+EWR +VL ++K + Y Sbjct: 71 VASSHISDANLANTIIGKAVEHMFE---GEHG---SKDEWRGMVLAQAPIMKAWFYITYE 124 Query: 208 KD 209 KD Sbjct: 125 KD 126 >3TZ1-A nrPDB Length = 74 Score = 26.9 bits (58), Expect = 6.7, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 8/71 (11%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +F++ D +++G I + +V + ++ +L D + ED I+ E DT G +D E Sbjct: 12 AFRVLDKEKKGVI-KVDVLRWILKSLG-------DELTEDEIENMIAETDTDGSGTVDYE 63 Query: 187 EWRSLVLRHPS 197 E++ L++ + Sbjct: 64 EFKCLMMSSDA 74 >1NYA-A nrPDB Length = 176 Score = 26.9 bits (58), Expect = 7.1, Method: Compositional matrix adjust. Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 5/54 (9%) Query: 64 DGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFH 115 DG IN +EF L +K E A F+ DT NG L +E A+ FH Sbjct: 116 DGQINADEFAAWLTALGMSKAE---AAEAFNQVDTNGNGELSLDELLTAVRDFH 166 >3O4Y-A nrPDB Length = 196 Score = 26.9 bits (58), Expect = 7.6, Method: Compositional matrix adjust. Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 7/106 (6%) Query: 88 DRVFDLFDTKHNGILGFEEF-ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 D + D D+ +G + + EF A A+ + + I+ +F+++D+ G I E+ Sbjct: 93 DLLLDQIDSDGSGNIDYTEFLAAAIDRRQLSKKL---IYCAFRVFDVDNDGEITTAELAH 149 Query: 147 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 ++ + +D + + K E D DGKID E+ ++ Sbjct: 150 VLFNGNKRGNITERDV---NQVKKMIREVDKNGDGKIDFYEFSEMM 192 >2K2I-A nrPDB Length = 79 Score = 26.9 bits (58), Expect = 8.0, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 9/72 (12%) Query: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 +F+L+D + G I + +K++ E G NL D ++++ID EAD DG++ ++ Sbjct: 16 AFKLFDDDETGKISFKNLKRVA----KELGENLTDEELQEMID----EADRDGDGEVSEQ 67 Query: 187 EWRSLVLRHPSL 198 E+ +++ SL Sbjct: 68 EFLR-IMKKTSL 78 >4MSP-A nrPDB Length = 200 Score = 26.6 bits (57), Expect = 8.3, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 7/64 (10%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK----DTVIEDIIDKTF 172 N P + H SFQ DL + + EVK + + G + D ++EDI DK Sbjct: 125 NGP---RSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKED 181 Query: 173 EEAD 176 E+ D Sbjct: 182 EDKD 185 >1S36-A nrPDB Length = 195 Score = 26.6 bits (57), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/61 (24%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 + D VFD+FD +G + +E+ +A +P + +F+ DL G ++ E+ Sbjct: 114 WGDAVFDIFDKDGSGTITLDEW-KAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMT 172 Query: 146 Q 146 + Sbjct: 173 R 173 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2ZFD-A nrPDB 299 6e-82 1V1G-A nrPDB 237 3e-63 1UHN-A nrPDB 226 4e-60 5T7C-A nrPDB 196 6e-51 1BJF-A nrPDB 192 1e-49 2JUL-A nrPDB 191 3e-49 5M6C-E nrPDB 189 8e-49 2LCP-A nrPDB 189 9e-49 2L2E-A nrPDB 188 2e-48 6EPA-A nrPDB 184 3e-47 1S6C-A nrPDB 182 1e-46 1S1E-A nrPDB 181 2e-46 3DD4-A nrPDB 181 2e-46 2JU0-A nrPDB 171 3e-43 4IL1-A nrPDB 160 3e-40 2GGZ-A nrPDB 158 2e-39 2NA0-A nrPDB 156 8e-39 2R2I-A nrPDB 154 2e-38 2I94-A nrPDB 154 3e-38 1JBA-A nrPDB 153 6e-38 4ORC-B nrPDB 150 5e-37 2D8N-A nrPDB 150 6e-37 3U0K-A nrPDB 147 3e-36 5B8I-B nrPDB 146 9e-36 4OY4-A nrPDB 145 1e-35 3EK4-A nrPDB 144 2e-35 2BEC-A nrPDB 144 3e-35 2E30-A nrPDB 140 6e-34 2N6A-A nrPDB 135 2e-32 3WFN-B nrPDB 134 2e-32 2F2P-A nrPDB 131 3e-31 6O20-F nrPDB 130 4e-31 4E53-A nrPDB 129 1e-30 5YPX-A nrPDB 129 1e-30 6HCS-A nrPDB 125 1e-29 5A2H-A nrPDB 124 3e-29 5I0I-E nrPDB 122 9e-29 1DGU-A nrPDB 119 1e-27 2LM5-A nrPDB 118 2e-27 2L1W-A nrPDB 112 9e-26 5ZOR-A nrPDB 112 2e-25 3KF9-A nrPDB 102 9e-23 Sequences not found previously or not previously below threshold: 4I2Y-A nrPDB 135 1e-32 5UKG-A nrPDB 134 4e-32 1CLM-A nrPDB 120 5e-28 1GGZ-A nrPDB 114 3e-26 2E6W-A nrPDB 104 3e-23 5D43-A nrPDB 99 1e-21 3QRX-A nrPDB 98 3e-21 2GGM-A nrPDB 97 4e-21 2LMV-A nrPDB 94 6e-20 2OBH-A nrPDB 92 1e-19 2LHI-A nrPDB 89 1e-18 4DS7-A nrPDB 87 5e-18 1LKJ-A nrPDB 85 3e-17 1TOP-A nrPDB 84 4e-17 2TN4-A nrPDB 84 5e-17 1DTL-A nrPDB 82 1e-16 3K21-A nrPDB 79 1e-15 4RGJ-A nrPDB 79 1e-15 3HZT-A nrPDB 79 1e-15 4JWQ-A nrPDB 79 2e-15 2KN2-A nrPDB 77 5e-15 5JN2-A nrPDB 77 8e-15 3O4Y-A nrPDB 76 1e-14 2HF5-A nrPDB 76 1e-14 1FW4-A nrPDB 76 1e-14 2LAP-A nrPDB 76 1e-14 3LIJ-A nrPDB 75 2e-14 2LHH-A nrPDB 75 2e-14 2KZ2-A nrPDB 75 3e-14 4YZB-A nrPDB 74 4e-14 2RO9-A nrPDB 74 5e-14 4MVF-A nrPDB 74 7e-14 3Q5I-A nrPDB 73 9e-14 2ROB-A nrPDB 73 1e-13 1S6I-A nrPDB 72 1e-13 3KHE-A nrPDB 72 2e-13 3FWC-A nrPDB 72 2e-13 2M5E-A nrPDB 72 3e-13 1M39-A nrPDB 71 3e-13 3NCG-A nrPDB 71 3e-13 3PM8-A nrPDB 71 4e-13 3L19-A nrPDB 71 4e-13 2JNF-A nrPDB 70 6e-13 2AAO-A nrPDB 70 9e-13 2M29-A nrPDB 69 2e-12 2BL0-C nrPDB 69 2e-12 3IFK-A nrPDB 67 8e-12 2LC5-A nrPDB 66 9e-12 2JNX-A nrPDB 63 1e-10 5E37-A nrPDB 62 1e-10 5MWC-D nrPDB 62 2e-10 2K2I-A nrPDB 62 2e-10 2B1U-A nrPDB 60 5e-10 1JFJ-A nrPDB 60 5e-10 3E3R-A nrPDB 60 7e-10 2LV7-A nrPDB 60 8e-10 4N5X-A nrPDB 60 1e-09 4ZCV-A nrPDB 60 1e-09 4WPX-A nrPDB 59 2e-09 5COC-A nrPDB 59 2e-09 5H7D-E nrPDB 58 4e-09 2Q4U-A nrPDB 57 8e-09 3J04-B nrPDB 56 1e-08 3AAJ-A nrPDB 56 1e-08 2BL0-B nrPDB 55 2e-08 2RO8-A nrPDB 55 3e-08 1JC2-A nrPDB 54 4e-08 2I08-A nrPDB 54 4e-08 2K7C-A nrPDB 54 5e-08 2AMI-A nrPDB 54 6e-08 4Q57-A nrPDB 54 6e-08 1OQP-A nrPDB 54 6e-08 2K2A-A nrPDB 53 8e-08 1OZS-A nrPDB 53 1e-07 2M97-A nrPDB 52 1e-07 1C7W-A nrPDB 52 2e-07 5OTJ-D nrPDB 52 2e-07 6IIE-A nrPDB 52 2e-07 1SR6-C nrPDB 52 2e-07 5JOJ-A nrPDB 51 5e-07 5ZGM-A nrPDB 50 5e-07 5JOL-A nrPDB 50 6e-07 2KSZ-A nrPDB 50 6e-07 2G9B-A nrPDB 50 7e-07 2LVK-A nrPDB 49 1e-06 1Y1X-A nrPDB 49 1e-06 5PAL-A nrPDB 49 2e-06 1YX7-A nrPDB 49 2e-06 1ZMZ-A nrPDB 48 4e-06 2OPO-A nrPDB 47 5e-06 2NCO-A nrPDB 47 5e-06 1W7I-B nrPDB 47 5e-06 3I5H-B nrPDB 47 6e-06 1F55-A nrPDB 47 6e-06 4MSP-A nrPDB 47 6e-06 5XND-A nrPDB 47 6e-06 1TRF-A nrPDB 47 8e-06 1TNP-A nrPDB 47 8e-06 3TZ1-A nrPDB 47 8e-06 5H53-C nrPDB 47 8e-06 1H4B-A nrPDB 47 9e-06 2M8U-A nrPDB 47 9e-06 2N7L-C nrPDB 47 1e-05 3DTP-E nrPDB 46 1e-05 2KYF-A nrPDB 46 1e-05 4D1E-A nrPDB 46 1e-05 5VLN-A nrPDB 46 1e-05 1IJ5-A nrPDB 46 1e-05 4P5W-A nrPDB 45 2e-05 1SJJ-A nrPDB 45 2e-05 1GGW-A nrPDB 45 2e-05 5E1J-A nrPDB 45 2e-05 1JF0-A nrPDB 45 3e-05 1I84-U nrPDB 45 3e-05 6EAZ-A nrPDB 45 3e-05 3PAT-A nrPDB 45 3e-05 2N8Y-A nrPDB 45 4e-05 1QX2-A nrPDB 44 4e-05 1O1A-B nrPDB 44 4e-05 3LCP-C nrPDB 44 5e-05 2VRG-A nrPDB 44 5e-05 3A4U-B nrPDB 44 5e-05 5TBY-E nrPDB 44 7e-05 3KPX-A nrPDB 44 7e-05 5TBY-C nrPDB 44 8e-05 3JAX-C nrPDB 43 9e-05 6FSA-D nrPDB 43 9e-05 4P5X-A nrPDB 43 9e-05 4L9M-A nrPDB 43 1e-04 4YGB-B nrPDB 43 1e-04 1B7T-Y nrPDB 43 1e-04 2HPS-A nrPDB 43 1e-04 4GJF-A nrPDB 43 1e-04 3SIA-A nrPDB 42 1e-04 4OKH-A nrPDB 42 2e-04 3AKA-A nrPDB 42 2e-04 1QXP-A nrPDB 42 2e-04 5ZH6-A nrPDB 42 2e-04 2OS8-B nrPDB 42 2e-04 1A75-A nrPDB 42 2e-04 2KQY-A nrPDB 42 2e-04 1S36-A nrPDB 42 2e-04 5Z1Q-A nrPDB 42 2e-04 3I5I-C nrPDB 42 2e-04 5XOP-A nrPDB 41 4e-04 3JBH-C nrPDB 41 4e-04 5B7X-A nrPDB 41 4e-04 6MI5-X nrPDB 41 4e-04 3MSE-B nrPDB 41 4e-04 1RTP-1 nrPDB 41 4e-04 1N2D-A nrPDB 41 5e-04 2JOJ-A nrPDB 40 7e-04 5VE9-A nrPDB 40 7e-04 2K7B-A nrPDB 40 7e-04 4NQG-A nrPDB 40 7e-04 1TIZ-A nrPDB 40 7e-04 1NYA-A nrPDB 40 8e-04 1DFK-Y nrPDB 40 9e-04 5CPV-A nrPDB 40 9e-04 2MA2-A nrPDB 40 9e-04 2LVV-A nrPDB 40 0.001 5I2L-A nrPDB 40 0.001 2I18-A nrPDB 39 0.001 2SAS-A nrPDB 39 0.001 1TTX-A nrPDB 39 0.001 1SL8-A nrPDB 39 0.002 1S6J-A nrPDB 39 0.002 1F4Q-A nrPDB 39 0.002 1BU3-A nrPDB 39 0.002 1CB1-A nrPDB 39 0.002 2EC6-B nrPDB 39 0.002 1RK9-A nrPDB 39 0.002 2WCE-A nrPDB 39 0.002 1BOD-A nrPDB 38 0.002 1Q80-A nrPDB 38 0.002 6AGH-A nrPDB 38 0.003 2FCE-A nrPDB 38 0.003 1JUO-A nrPDB 38 0.003 1G33-A nrPDB 38 0.003 1ZFS-A nrPDB 38 0.003 2NLN-A nrPDB 38 0.003 5H53-B nrPDB 38 0.003 5VT9-A nrPDB 38 0.003 2LUC-A nrPDB 38 0.003 2PMY-A nrPDB 38 0.003 4OCI-A nrPDB 38 0.004 2W4G-C nrPDB 38 0.004 4PAL-A nrPDB 38 0.004 2L50-A nrPDB 38 0.004 3A8R-A nrPDB 38 0.004 5MRA-A nrPDB 38 0.004 1QLS-A nrPDB 38 0.005 1UHK-A nrPDB 37 0.005 2M7M-A nrPDB 37 0.006 3TS5-B nrPDB 37 0.007 1NSH-A nrPDB 37 0.008 3BOW-B nrPDB 36 0.015 2L0P-A nrPDB 36 0.017 1GJY-A nrPDB 35 0.019 2MBX-A nrPDB 35 0.021 4NSC-A nrPDB 35 0.022 1KQV-A nrPDB 35 0.029 1KFU-L nrPDB 35 0.036 3DF0-A nrPDB 34 0.047 2M1U-A nrPDB 34 0.048 4C0K-A nrPDB 34 0.050 6AGI-A nrPDB 34 0.054 6DS2-B nrPDB 34 0.055 5CSF-A nrPDB 34 0.062 5HYD-A nrPDB 33 0.076 3CS1-A nrPDB 33 0.077 2AUC-A nrPDB 33 0.084 2KGR-A nrPDB 33 0.085 4FTG-A nrPDB 33 0.13 3H4S-E nrPDB 33 0.13 4HRG-A nrPDB 33 0.14 2MHH-A nrPDB 33 0.14 2Y5I-A nrPDB 33 0.15 2MJW-B nrPDB 32 0.16 4AOM-A nrPDB 32 0.19 1KFX-S nrPDB 32 0.20 2JXC-A nrPDB 32 0.31 1WY9-A nrPDB 32 0.31 5X2E-A nrPDB 32 0.33 5HLO-A nrPDB 31 0.49 1NUB-A nrPDB 31 0.51 3TQO-A nrPDB 30 0.58 2VTG-A nrPDB 30 0.71 2JQ6-A nrPDB 30 0.79 5W1A-B nrPDB 30 0.82 2KFH-A nrPDB 30 0.92 1NP8-A nrPDB 30 1.0 4MDC-A nrPDB 30 1.2 4I5L-B nrPDB 29 1.3 1SRA-A nrPDB 29 1.5 4YBH-B nrPDB 29 1.5 2NS2-A nrPDB 29 1.6 1Z5V-A nrPDB 29 1.6 1C4O-A nrPDB 29 1.9 2QPT-A nrPDB 29 1.9 1SNL-A nrPDB 29 2.1 4MEW-A nrPDB 29 2.1 2KHN-A nrPDB 28 2.2 4PEM-A nrPDB 28 2.2 4PEL-A nrPDB 28 2.2 1DJX-A nrPDB 28 2.2 5MKE-A nrPDB 28 2.3 4CJ1-A nrPDB 28 2.3 4D10-D nrPDB 28 2.3 5NF4-A nrPDB 28 2.5 6I8Y-A nrPDB 28 2.6 4DUQ-A nrPDB 28 2.7 6D1W-A nrPDB 28 2.7 3FZI-A nrPDB 28 3.0 4W7S-A nrPDB 28 3.1 5L0P-A nrPDB 28 3.3 4H9M-A nrPDB 28 3.6 3S8P-A nrPDB 28 3.6 2JTT-A nrPDB 28 4.0 5ZWN-y nrPDB 28 4.3 5MVF-A nrPDB 27 4.8 2QXL-A nrPDB 27 5.1 4A0G-A nrPDB 27 5.2 5FM1-C nrPDB 27 5.3 5Z6Z-A nrPDB 27 5.3 5Z2T-C nrPDB 27 5.3 4D0P-A nrPDB 27 5.5 5VC2-A nrPDB 27 5.5 6G18-t nrPDB 27 5.6 1QJT-A nrPDB 27 5.6 4FL4-A nrPDB 27 5.7 2YY5-A nrPDB 27 5.9 3X0D-A nrPDB 27 6.1 2Y3N-B nrPDB 27 6.3 5VP3-A nrPDB 27 7.0 4I0B-A nrPDB 27 7.0 3KCC-A nrPDB 27 7.0 1FI6-A nrPDB 27 8.5 1L9X-A nrPDB 27 8.6 4U3S-B nrPDB 27 8.8 5LPU-C nrPDB 27 9.1 4I5K-A nrPDB 27 9.6 4UQF-A nrPDB 27 9.6 6GYL-Q nrPDB 27 9.8 >2ZFD-A nrPDB Length = 226 Score = 299 bits (766), Expect = 6e-82, Method: Composition-based stats. Identities = 226/226 (100%), Positives = 226/226 (100%) Query: 1 MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSA 60 MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSA Sbjct: 1 MSQCVDGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSA 60 Query: 61 VIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 VIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI Sbjct: 61 VIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD Sbjct: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 Query: 181 GKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT 226 GKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT Sbjct: 181 GKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT 226 >1V1G-A nrPDB Length = 222 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 119/200 (59%), Positives = 157/200 (78%) Query: 26 QSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL 85 + G DPELLA T F+V E+EALYELFKK+SS++IDDGLI+KEEFQLALF+ + +L Sbjct: 15 RPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNL 74 Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 FADR+FD+FD K NG++ F EF R+L VFHP+AP+ +K+ F+F+LYDL+Q GFIER+E+K Sbjct: 75 FADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELK 134 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 +MVVA L ES + L + +IE ++DK F +AD K+DGKID +EW+ V +PSL+KNMTL Sbjct: 135 EMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKNMTLP 194 Query: 206 YLKDITTTFPSFVFHSQVED 225 YLKDI TFPSFV + E+ Sbjct: 195 YLKDINRTFPSFVSSCEEEE 214 >1UHN-A nrPDB Length = 189 Score = 226 bits (577), Expect = 4e-60, Method: Composition-based stats. Identities = 189/189 (100%), Positives = 189/189 (100%) Query: 32 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 91 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 60 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT Sbjct: 61 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 120 Query: 152 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDIT 211 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDIT Sbjct: 121 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDIT 180 Query: 212 TTFPSFVFH 220 TTFPSFVFH Sbjct: 181 TTFPSFVFH 189 >5T7C-A nrPDB Length = 193 Score = 196 bits (499), Expect = 6e-51, Method: Composition-based stats. Identities = 53/176 (30%), Positives = 86/176 (48%), Gaps = 11/176 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 + L +T F+ E++ Y+ F K G + +EF+ A F S FA+ VF Sbjct: 14 QDLRENTEFTDHELQEWYKGFLKDCPT----GHLTVDEFKKIYANFFPYGDASKFAEHVF 69 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 FDT +G + F EF ALSV ++ K+ ++F +YDL G+I R E+ ++V A Sbjct: 70 RTFDTNGDGTIDFREFIIALSV-TSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAI 128 Query: 152 LAESGMNLK----DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 +K ++ E DK F + DT +DGK+ EE+ PS+++ + Sbjct: 129 YKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQ 184 >1BJF-A nrPDB Length = 193 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 11/176 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 + L T F+ EI+ Y+ F + + G ++ EEF+ F S FA+ VF Sbjct: 14 QDLLESTDFTEHEIQEWYKGFLRDCPS----GHLSMEEFKKIYGNFFPYGDASKFAEHVF 69 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 FD +G + F EF ALSV ++ K+ ++F +YDL G+I + E+ ++V A Sbjct: 70 RTFDANGDGTIDFREFIIALSV-TSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAI 128 Query: 152 LAESGMNLK----DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 +K ++ E +K F + DT DGK+ EE+ PS+++ + Sbjct: 129 YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQ 184 >2JUL-A nrPDB Length = 256 Score = 191 bits (484), Expect = 3e-49, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 87/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 + L T F+ E+++LY FK GL++++ F+ + F + +A +F Sbjct: 80 DQLQAQTKFTKKELQSLYRGFKNECPT----GLVDEDTFKLIYSQFFPQGDATTYAHFLF 135 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FD NG + FE+F LS+ + +K+ ++F LYD+ + G I ++E+ ++ + Sbjct: 136 NAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 Query: 152 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + + ED +++ F++ D DG + +E+ + +++ +M L Sbjct: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 >5M6C-E nrPDB Length = 193 Score = 189 bits (480), Expect = 8e-49, Method: Composition-based stats. Identities = 54/176 (30%), Positives = 89/176 (50%), Gaps = 11/176 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 + L +T FS E++ Y+ F K G++N +EF+ A F S FA+ VF Sbjct: 14 QDLRENTEFSELELQEWYKGFLKDCPT----GILNVDEFKKIYANFFPYGDASKFAEHVF 69 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 FDT +G + F EF ALSV ++ K+ ++F +YDL G+I R+E+ ++V A Sbjct: 70 RNFDTNSDGTIDFREFIIALSV-TSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAI 128 Query: 152 LAESGMNLK----DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 +K ++ E +K F + DT +DGK+ EE+ PS+++ + Sbjct: 129 YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQ 184 >2LCP-A nrPDB Length = 190 Score = 189 bits (480), Expect = 9e-49, Method: Composition-based stats. Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L R T F+ E++ Y+ F K + G ++ FQ F + FA VF Sbjct: 14 EELTRKTYFTEKEVQQWYKGFIKDCPS----GQLDAAGFQKIYKQFFPFGDPTKFATFVF 69 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 ++FD +G + F EF +ALSV +D+K+ ++F+LYDL G+I R E+ +V A Sbjct: 70 NVFDENKDGRIEFSEFIQALSV-TSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAI 128 Query: 152 LAESGMNL----KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + ++ E +D+ F D DGK+ +E++ PS+++ ++L Sbjct: 129 YQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSL 185 >2L2E-A nrPDB Length = 190 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 57/177 (32%), Positives = 88/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 + L R T F E++ Y+ F K + G +NK EFQ F S FA+ VF Sbjct: 14 QDLVRSTRFDKKELQQWYKGFFKDCPS----GHLNKSEFQKIYKQFFPFGDPSAFAEYVF 69 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 ++FD NG + F+EF ALSV ++DK+ ++FQLYDL G I E+ ++V A Sbjct: 70 NVFDADKNGYIDFKEFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128 Query: 152 LAESGMNLK----DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G +K + E ++K F D DG++ EE+ R P+++ ++L Sbjct: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSL 185 >6EPA-A nrPDB Length = 187 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 53/176 (30%), Positives = 92/176 (52%), Gaps = 10/176 (5%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 + L DT F+ EI ++ F K +GL+ ++ F F + S FA VF Sbjct: 14 DRLTTDTYFTEKEIRQWHKGFLKDCP----NGLLTEQGFIKIYKQFFPDGDPSKFASLVF 69 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 +FD ++G + FEEF RALS+ +D+K+H++F+LYD+ G+I R+E+ +V A Sbjct: 70 RVFDENNDGAIEFEEFIRALSI-TSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAI 128 Query: 152 LAESGMNLK---DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G + + + +DK F++ D HD ++ EE+R P +++ ++L Sbjct: 129 YQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSL 184 >1S6C-A nrPDB Length = 183 Score = 182 bits (461), Expect = 1e-46, Method: Composition-based stats. Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L T F+ E++ LY FK + G++N+E F+ A F + S +A +F Sbjct: 7 EQLEAQTNFTKRELQVLYRGFKNECPS----GVVNEETFKQIYAQFFPHGDASTYAHYLF 62 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FDT G + FE+F ALS+ + +K+ ++F LYD+ + G+I ++E+ +V A Sbjct: 63 NAFDTTQTGSVKFEDFVTALSILL-RGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 121 Query: 152 LAESGMN----LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G LK+ +D F++ D DG + +E+ ++++++ L Sbjct: 122 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQL 178 >1S1E-A nrPDB Length = 224 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L T F+ E++ LY FK + G++N+E F+ A F + S +A +F Sbjct: 40 EQLEAQTNFTKRELQVLYRGFKNECPS----GVVNEETFKQIYAQFFPHGDASTYAHYLF 95 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FDT G + FE+F ALS+ + +K+ ++F LYD+ + G+I ++E+ +V A Sbjct: 96 NAFDTTQTGSVKFEDFVTALSILL-RGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 154 Query: 152 LAESGMN----LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G LK+ +D F++ D DG + +E+ ++++++ L Sbjct: 155 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQL 211 >3DD4-A nrPDB Length = 229 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 46/177 (25%), Positives = 92/177 (51%), Gaps = 11/177 (6%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 ELL + F+ E++ LY FK + G++N+E F+ + F + +A +F Sbjct: 53 ELLEAQSKFTKKELQILYRGFKNECPS----GVVNEETFKEIYSQFFPQGDSTTYAHFLF 108 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 + FDT HNG + FE+F + LS+ + +K++++F LYD+ + G+I ++E+ ++ A Sbjct: 109 NAFDTDHNGAVSFEDFIKGLSILL-RGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAI 167 Query: 152 LAESGMN----LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G LK+ ++ F++ D DG + +E+ + +++++M L Sbjct: 168 YDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQL 224 >2JU0-A nrPDB Length = 190 Score = 171 bits (432), Expect = 3e-43, Method: Composition-based stats. Identities = 47/175 (26%), Positives = 80/175 (45%), Gaps = 11/175 (6%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDL 93 L + T F EI+ ++ F + + G + +E+F F FA+ +F + Sbjct: 16 LKQSTYFDRREIQQWHKGFLRDCPS----GQLAREDFVKIYKQFFPFGSPEDFANHLFTV 71 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 FD +NG + FEEF LS +++K+ ++F+LYDL G+I E+ +V + Sbjct: 72 FDKDNNGFIHFEEFITVLST-TSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYK 130 Query: 154 ESGM----NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G N + E + K F+ D DG I +E+R PS++ + L Sbjct: 131 MMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNL 185 >4IL1-A nrPDB Length = 823 Score = 160 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 52/157 (33%), Positives = 86/157 (54%), Gaps = 8/157 (5%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFD 95 L + F EI+ L + FKK+ + + G ++ EEF + +++ RV D+FD Sbjct: 166 LEMCSHFDADEIKRLGKRFKKLD--LDNSGSLSVEEF---MSLPELQQNPLVQRVIDIFD 220 Query: 96 TKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 T NG + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ Sbjct: 221 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 277 Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 G NLKDT ++ I+DKT AD DG+I EE+ ++V Sbjct: 278 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 Score = 145 bits (366), Expect = 1e-35, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 6 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 59 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 111 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 60.1 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 63 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 64 IDFPEFLTMMARK 76 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 32/200 (16%), Positives = 60/200 (30%), Gaps = 56/200 (28%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 82 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 136 Query: 102 LGFEEFARALSVF---------------------HPNAPIDDKIHFSFQLYDLKQQGFIE 140 + +EEF + ++ H +A ++ F+ DL G + Sbjct: 137 VNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLS 196 Query: 141 RQE-----------VKQMVVATLAESGMNLKDTVIEDIIDKT----------------FE 173 +E + Q V+ G + ++ I+ F Sbjct: 197 VEEFMSLPELQQNPLVQRVIDIFDTDGN--GEVDFKEFIEGVSQFSVKGDKEQKLRFAFR 254 Query: 174 EADTKHDGKIDKEEWRSLVL 193 D DG I E ++ Sbjct: 255 IYDMDKDGYISNGELFQVLK 274 >2GGZ-A nrPDB Length = 211 Score = 158 bits (399), Expect = 2e-39, Method: Composition-based stats. Identities = 47/176 (26%), Positives = 84/176 (47%), Gaps = 10/176 (5%) Query: 28 GGLGDPELLARDTV-FSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKES 84 G +G+ + +A D E Y F + GL EF+ L L N+K + Sbjct: 1 GHMGNGKSIAGDQKAVPTQETHVWYRTFMMEYPS----GLQTLHEFKTLLGLQGLNQKAN 56 Query: 85 LFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 D+V++ FDT +G + F EF A+++ ++ K+ + F+LYD G I++ E+ Sbjct: 57 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM-QEKMEQKLKWYFKLYDADGNGSIDKNEL 115 Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 M +A A +G E+ I+ F + D +DG++ EE+ + + + LL+ Sbjct: 116 LDMFMAVQALNGQQT--LSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 169 >2NA0-A nrPDB Length = 205 Score = 156 bits (394), Expect = 8e-39, Method: Composition-based stats. Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 12/200 (6%) Query: 28 GGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESL 85 G + D + + S +E Y+ F + G + EF+ L + S Sbjct: 2 GNIMDGKSVEE---LSSTECHQWYKKFMTECPS----GQLTLYEFRQFFGLKNLSPWASQ 54 Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 + +++F+ FD +G + F E+ ALS+ ++ K+ + F+LYD+ G I+R E+ Sbjct: 55 YVEQMFETFDFNKDGYIDFMEYEAALSLVL-KGKVEQKLRWYFKLYDVDGNGCIDRDELL 113 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 ++ A A + + E+ D F + D DG++ EE+ V + LL +T Sbjct: 114 TIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRS 173 Query: 206 YLKDITTTFPSFVFHSQVED 225 D+T Q E+ Sbjct: 174 L--DLTRIVRRLQNGEQDEE 191 >2R2I-A nrPDB Length = 198 Score = 154 bits (390), Expect = 2e-38, Method: Composition-based stats. Identities = 41/165 (24%), Positives = 76/165 (46%), Gaps = 8/165 (4%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKH 98 S +E Y+ F + G + EF+ L + + + +++F+ FD Sbjct: 10 ELSATECHQWYKKFMTECPS----GQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNK 65 Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 +G + F E+ ALS+ +D K+ + F+LYD+ G I+R E+ ++ A A + N Sbjct: 66 DGYIDFMEYVAALSLVL-KGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCN 124 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 E+ + F++ D DG++ EE+ V + LL +T Sbjct: 125 EA-MTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILT 168 >2I94-A nrPDB Length = 202 Score = 154 bits (389), Expect = 3e-38, Method: Composition-based stats. Identities = 47/190 (24%), Positives = 82/190 (43%), Gaps = 15/190 (7%) Query: 26 QSGGLGDP--ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNK 81 +SG L E L +T F+ E+ + Y+ F K + G I ++EFQ + F Sbjct: 5 KSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPS----GRITRQEFQTIYSKFFPEA 60 Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 +A VF FD +G L F+E+ AL + + K+ ++F LYD+ G I + Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHM-TSAGKTNQKLEWAFSLYDVDGNGTISK 119 Query: 142 QEVKQMVVATLAESGMN------LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 EV ++V A + E +K + K D K+ ++E+ L + Sbjct: 120 NEVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLAN 179 Query: 196 PSLLKNMTLQ 205 +L+ + + Sbjct: 180 KEILRLIQFE 189 >1JBA-A nrPDB Length = 204 Score = 153 bits (386), Expect = 6e-38, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 79/172 (45%), Gaps = 15/172 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFADRVFDLFDTKHNGI 101 ++++ Y+ F + + G + EF+ N++ + + + +F FDT + Sbjct: 20 DAAQLQEWYKKFLEECPS----GTLFMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNT 75 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA-------- 153 + F E+ AL++ ++ K+ ++F++YD + G I+RQE+ +V + Sbjct: 76 IDFLEYVAALNLVL-RGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVE 134 Query: 154 -ESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 E+ K E+++D+ F D DG++ E+ R ++K + + Sbjct: 135 VEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQM 186 >4ORC-B nrPDB Length = 170 Score = 150 bits (378), Expect = 5e-37, Method: Composition-based stats. Identities = 52/157 (33%), Positives = 86/157 (54%), Gaps = 8/157 (5%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFD 95 L + F EI+ L + FKK+ + + G ++ EEF + +++ RV D+FD Sbjct: 9 LEMCSHFDADEIKRLGKRFKKLD--LDNSGSLSVEEF---MSLPELQQNPLVQRVIDIFD 63 Query: 96 TKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 T NG + F+EF +S F + K+ F+F++YD+ + G+I E+ Q++ Sbjct: 64 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 120 Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 G NLKDT ++ I+DKT AD DG+I EE+ ++V Sbjct: 121 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 34/87 (39%), Gaps = 14/87 (16%) Query: 108 ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 S F +A ++ F+ DL G + +E M+L + + Sbjct: 9 LEMCSHF--DADEIKRLGKRFKKLDLDNSGSLSVEEF------------MSLPELQQNPL 54 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + + DT +G++D +E+ V + Sbjct: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQ 81 >2D8N-A nrPDB Length = 207 Score = 150 bits (378), Expect = 6e-37, Method: Composition-based stats. Identities = 44/180 (24%), Positives = 80/180 (44%), Gaps = 13/180 (7%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L +T FS E+ + Y+ F K G I +++FQ A F + +A VF Sbjct: 22 EELQLNTKFSEEELCSWYQSFLKDCPT----GRITQQQFQSIYAKFFPDTDPKAYAQHVF 77 Query: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 FD+ +G L F+E+ AL + + K+ ++F LYD+ G I + EV ++V+A Sbjct: 78 RSFDSNLDGTLDFKEYVIALHMTTA-GKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAI 136 Query: 152 LAESGMN------LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 + E +K ++ D K+ ++E+ L + +L+ + + Sbjct: 137 FKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFE 196 >3U0K-A nrPDB Length = 442 Score = 147 bits (371), Expect = 3e-36, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 76/170 (44%), Gaps = 19/170 (11%) Query: 25 KQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKK 82 K G + L + ++E + + LF K DG I +E + N Sbjct: 287 KTKGWEPTRDQLTEEQ---IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPT 338 Query: 83 ESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQ 142 E+ D + ++ D +G + F EF ++ + +++I +F+++D G+I Sbjct: 339 EAELQDMINEV-DADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAA 397 Query: 143 EVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 E++ ++ NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 398 ELRHVM--------TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 62.8 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D DG Sbjct: 305 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGDGT 356 Query: 183 IDKEEWRSLVLRH 195 ID E+ ++ R Sbjct: 357 IDFPEFLIMMARK 369 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 375 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 429 Query: 102 LGFEEFARALSVF 114 + +EEF + ++ Sbjct: 430 VNYEEFVQMMTAK 442 >5B8I-B nrPDB Length = 171 Score = 146 bits (368), Expect = 9e-36, Method: Composition-based stats. Identities = 50/169 (29%), Positives = 85/169 (50%), Gaps = 9/169 (5%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFD 95 + + F E++ L++ F K+ G I ++EF L + + R+ +FD Sbjct: 9 IVSGSNFDHEEVDRLWKRFMKLDRD--KSGTIERDEF---LSLPQVSSNPLSTRMIAIFD 63 Query: 96 TKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 G + F+EF LS F ++K+ F+F++YD+ + GFI E+ ++ Sbjct: 64 EDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKM---MV 120 Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 G NLKD ++ I+DKT EAD DG+I EE+ +V + + +MTL Sbjct: 121 GSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMV-ENTDVSMSMTL 168 >4OY4-A nrPDB Length = 415 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 13 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 66 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 +G + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 67 GDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 118 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 63.1 bits (152), Expect = 8e-11, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D DG Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGDGT 70 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 71 IDFPEFLTMMARK 83 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 29/74 (39%), Gaps = 6/74 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 89 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 143 Query: 102 LGFEEFARALSVFH 115 + +EEF + ++ Sbjct: 144 VNYEEFVQMMTAKL 157 >3EK4-A nrPDB Length = 451 Score = 144 bits (364), Expect = 2e-35, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 308 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 361 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 362 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 413 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 414 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 Score = 63.9 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 41/101 (40%), Gaps = 15/101 (14%) Query: 102 LGFEEFARALSVFHPNAPIDD-------KIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 + F+E L D + +F L+D G I +E+ ++ + Sbjct: 286 IDFKEDGNILGHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL--- 342 Query: 155 SGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 G N + ++D+I+ E D +G ID E+ +++ R Sbjct: 343 -GQNPTEAELQDMIN----EVDADGNGTIDFPEFLTMMARK 378 Score = 45.0 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 384 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 438 Query: 102 LGFEEFARALSVF 114 + +EEF + ++ Sbjct: 439 VNYEEFVQMMTAK 451 >2BEC-A nrPDB Length = 202 Score = 144 bits (363), Expect = 3e-35, Method: Composition-based stats. Identities = 48/196 (24%), Positives = 89/196 (45%), Gaps = 27/196 (13%) Query: 30 LGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFAD 88 + D + + R+T FS + + L+ F+ + G +++ + Q + N D Sbjct: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQIGALAVNP----LGD 64 Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAPID----------------DKIHFSFQLYD 132 R+ + F + + F F R L+ F P D +K+H++FQLYD Sbjct: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 Query: 133 LKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 L + G I R E+ Q++ G+ + + +E+I D+T +EAD DG + E+ Sbjct: 125 LDRDGKISRHEMLQVLR---LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK-S 180 Query: 193 LRHPSLLKNMTLQYLK 208 L + + M+++ LK Sbjct: 181 LEKMDVEQKMSIRILK 196 >2E30-A nrPDB Length = 195 Score = 140 bits (352), Expect = 6e-34, Method: Composition-based stats. Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 24/189 (12%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDL 93 E + ++T FS S+I LY F + ++G +++E+FQ + DR+ + Sbjct: 15 EEIKKETGFSHSQITRLYSRFTSLDKG--ENGTLSREDFQRI---PELAINPLGDRIINA 69 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPID---------------DKIHFSFQLYDLKQQGF 138 F + + F F R L+ F P + +K+HF+F+LYDL + Sbjct: 70 FFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEK 129 Query: 139 IERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSL 198 I R E+ Q++ G+N+ D + I D+T +EAD D I E+ VL + Sbjct: 130 ISRDELLQVLRM---MVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVK-VLEKVDV 185 Query: 199 LKNMTLQYL 207 + M++++L Sbjct: 186 EQKMSIRFL 194 >4I2Y-A nrPDB Length = 421 Score = 135 bits (340), Expect = 1e-32, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 70/155 (45%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 278 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 331 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 +G F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 332 GDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVM--------T 383 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 +L + + ++ +D+ AD DG+++ EE+ ++ Sbjct: 384 DLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 61.2 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D DG Sbjct: 284 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGDGT 335 Query: 183 IDKEEWRSLVLRH 195 D E+ +++ R Sbjct: 336 FDFPEFLTMMARK 348 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I E + + +K D + + D +G Sbjct: 354 SEEEIREAFRVFDKDG-----NGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQ 408 Query: 102 LGFEEFARALSVF 114 + +EEF + ++ Sbjct: 409 VNYEEFVQMMTAK 421 >2N6A-A nrPDB Length = 173 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 7 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 60 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 61 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 112 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 113 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 64 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 65 IDFPEFLTMMARK 77 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 83 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 137 Query: 102 LGFEEFARALS 112 + +EEF + ++ Sbjct: 138 VNYEEFVQMMT 148 >3WFN-B nrPDB Length = 182 Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 12 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 65 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 66 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 117 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 118 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 55.8 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 69 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 70 IDFPEFLTMMARK 82 >5UKG-A nrPDB Length = 419 Score = 134 bits (336), Expect = 4e-32, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 69/155 (44%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 276 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 329 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 +G F EF ++ +++I +F+++D G+I E++ ++ Sbjct: 330 GDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVM--------T 381 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 +L + + ++ +D+ AD DG+++ EE+ ++ Sbjct: 382 DLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D DG Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGDGT 333 Query: 183 IDKEEWRSLVLRH 195 D E+ +++ R Sbjct: 334 FDFPEFLTMMARK 346 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 6/75 (8%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHN 99 + EI + +F K +G I E + + +K D + + D + Sbjct: 350 RVTEEEIREAFRVFDKDG-----NGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGD 404 Query: 100 GILGFEEFARALSVF 114 G + +EEF + ++ Sbjct: 405 GQVNYEEFVQMMTAK 419 >2F2P-A nrPDB Length = 179 Score = 131 bits (329), Expect = 3e-31, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 6 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 59 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 111 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 63 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 64 IDFPEFLTMMARK 76 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 82 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 136 Query: 102 LGFEEFARALSVF 114 + +EEF + ++ Sbjct: 137 VNYEEFVQMMTAK 149 >6O20-F nrPDB Length = 169 Score = 130 bits (328), Expect = 4e-31, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 26 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 79 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 80 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 131 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 132 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 83 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 84 IDFPEFLTMMARK 96 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 102 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 156 Query: 102 LGFEEFARALSVF 114 + +EEF + ++ Sbjct: 157 VNYEEFVQMMTAK 169 >4E53-A nrPDB Length = 185 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 13 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 66 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 67 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 118 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 53.5 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 70 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 71 IDFPEFLTMMARK 83 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 41/104 (39%), Gaps = 13/104 (12%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 89 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 143 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 + +EEF + ++ KI SF+ G I R+++K Sbjct: 144 VNYEEFVQMMTAKGGGGGAATKIQASFR-------GHITRKKLK 180 >5YPX-A nrPDB Length = 223 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 47/165 (28%), Positives = 83/165 (50%), Gaps = 7/165 (4%) Query: 39 DTVFSVSEIEALYELFKKISSAV-IDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTK 97 F+ +E+E+L +K + + +D L Q K N E L DRVF FD Sbjct: 38 QKHFTKTEVESLIICYKNLLEGLKMDRNLFRDILHQ----KFNMTEDLLMDRVFRAFDKD 93 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 + + E+ LSVF +D+K+ ++F ++DL G+I R+E+ QM+ L + Sbjct: 94 SDSYISLTEWVEGLSVFL-RGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPT 152 Query: 158 NL-KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKN 201 D I+D+++ ++ D HD ++ K++++ VL P LL+ Sbjct: 153 EEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLIEPLLLEA 197 >6HCS-A nrPDB Length = 167 Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 6 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 59 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ + Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFM--------T 111 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 63 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 64 IDFPEFLTMMARK 76 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 31/80 (38%), Gaps = 6/80 (7%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 82 SEEEIREAFRVFDKDG-----NGYISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQ 136 Query: 102 LGFEEFARALSVFHPNAPID 121 + +EEF + ++ ++ Sbjct: 137 VNYEEFVQMMTAKLEGTGLE 156 >5A2H-A nrPDB Length = 149 Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats. Identities = 36/154 (23%), Positives = 73/154 (47%), Gaps = 16/154 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 +SE + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 10 ISEFKEAFSLFDKDG-----DGCITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 63 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF ++ + ++++ +F+++D Q GFI E++ ++ NL + Sbjct: 64 IDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVM--------TNLGE 115 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 + ++ +D+ EAD DG+I+ EE+ +++ Sbjct: 116 KLTDEEVDEMIREADVDGDGQINYEEFVKVMMAK 149 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 29/70 (41%), Gaps = 6/70 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S E++ + +F K +G I+ E + + +K D + D +G Sbjct: 82 SEEELKEAFRVFDKD-----QNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQ 136 Query: 102 LGFEEFARAL 111 + +EEF + + Sbjct: 137 INYEEFVKVM 146 >5I0I-E nrPDB Length = 145 Score = 122 bits (307), Expect = 9e-29, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 71/155 (45%), Gaps = 16/155 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + L K DG I +E + N E+ D + ++ D Sbjct: 4 TEEQIAEFKEAFSLADKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 57 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D G+I E++ ++ Sbjct: 58 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------T 109 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + ++ +D+ EAD DG+++ EE+ ++ Sbjct: 110 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 61 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 62 IDFPEFLTMMARK 74 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 80 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 134 Query: 102 LGFEEFARALS 112 + +EEF + ++ Sbjct: 135 VNYEEFVQMMT 145 >1CLM-A nrPDB Length = 148 Score = 120 bits (301), Expect = 5e-28, Method: Composition-based stats. Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%) Query: 37 ARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLF 94 T ++E + + LF K DG I +E + N E+ D + ++ Sbjct: 2 QELTEEQIAEFKEAFALFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV- 55 Query: 95 DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 D NG + F EF ++ ++++ +F+++D G I E++ ++ Sbjct: 56 DADGNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVM------ 109 Query: 155 SGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 NL + + +D +D+ EAD DG I+ EE+ ++ Sbjct: 110 --TNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMM 145 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 62 Query: 183 IDKEEWRSLVLRH 195 ID E+ SL+ R Sbjct: 63 IDFPEFLSLMARK 75 >1DGU-A nrPDB Length = 183 Score = 119 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 42/170 (24%), Positives = 78/170 (45%), Gaps = 5/170 (2%) Query: 40 TVFSVSEIEALYELFKKISSAV---IDDGLINKEEFQLALFKTNKKESLFADRVFDLFDT 96 T + EI + F ++ ++ L + F+ L K + F +R+ +F T Sbjct: 12 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 71 Query: 97 K-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 L FE+F LSVF A D K H++F+++D G + R+++ ++V E Sbjct: 72 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 131 Query: 156 -GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 L + ++ +ID EE+D DG I+ E++ ++ R P + + Sbjct: 132 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 181 >2LM5-A nrPDB Length = 214 Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats. Identities = 42/170 (24%), Positives = 78/170 (45%), Gaps = 5/170 (2%) Query: 40 TVFSVSEIEALYELFKKISSAV---IDDGLINKEEFQLALFKTNKKESLFADRVFDLFDT 96 T + EI + F ++ ++ L + F+ L K + F +R+ +F T Sbjct: 43 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 102 Query: 97 K-HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 L FE+F LSVF A D K H++F+++D G + R+++ ++V E Sbjct: 103 SPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEG 162 Query: 156 -GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 L + ++ +ID EE+D DG I+ E++ ++ R P + + Sbjct: 163 EDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKI 212 >1GGZ-A nrPDB Length = 148 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 16/154 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T V+E + + LF K DG I E + N E+ D + ++ D Sbjct: 5 TEEQVTEFKEAFSLFDKDG-----DGCITTRELGTVMRSLGQNPTEAELRDMMSEI-DRD 58 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 NG + F EF ++ + +++I +F+++D GF+ E++ ++ Sbjct: 59 GNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVM--------T 110 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 L + + ++ +D+ ADT DG+++ EE+ + Sbjct: 111 RLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRV 144 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + + D+ E D +G Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSL----GQNPTEAELRDM----MSEIDRDGNGT 62 Query: 183 IDKEEWRSLVLRH 195 +D E+ ++ R Sbjct: 63 VDFPEFLGMMARK 75 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGIL 102 EI + +F K +G ++ E + + + +K D + DT +G + Sbjct: 82 EEEIREAFRVFDKDG-----NGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQV 136 Query: 103 GFEEFARAL 111 +EEF R L Sbjct: 137 NYEEFVRVL 145 >2L1W-A nrPDB Length = 149 Score = 112 bits (281), Expect = 9e-26, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 73/150 (48%), Gaps = 16/150 (10%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGILG 103 + + + LF K DG I EE + N E D + ++ D NG + Sbjct: 11 DFKEAFGLFDKDG-----DGCITVEELATVIRSLDQNPTEEELQDMISEV-DADGNGTIE 64 Query: 104 FEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTV 163 F+EF ++ + ++++ +F+++D Q G+I E++ +++ NL + + Sbjct: 65 FDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMI--------NLGEKL 116 Query: 164 IEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 ++ +++ +EAD DG+++ EE+ +++ Sbjct: 117 TDEEVEQMIKEADLDGDGQVNYEEFVKMMM 146 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 125 HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKID 184 +F L+D G I +E+ ++ + N + ++D+I E D +G I+ Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSL----DQNPTEEELQDMI----SEVDADGNGTIE 64 Query: 185 KEEWRSLVLRH 195 +E+ SL+ + Sbjct: 65 FDEFLSLMAKK 75 >5ZOR-A nrPDB Length = 149 Score = 112 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 74/156 (47%), Gaps = 19/156 (12%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLAL----FKTNKKESLFADRVFDLFDTKH 98 + +I + LF S G I+ EE LA+ F ++ +R +T Sbjct: 5 TDEQIREAFNLFDADGS-----GAIDAEEMALAMKGLGFGDLPRDE--VERTVRSMNTNA 57 Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 NG++ + EF R + +++ +FQL+DL ++G I +K++ G N Sbjct: 58 NGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLL----GEN 113 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 D V++++I EAD DG++ EE++S++++ Sbjct: 114 PGDDVLQEMI----AEADEDGDGEVSFEEFKSVMMQ 145 Score = 33.5 bits (75), Expect = 0.076, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 26/75 (34%), Gaps = 4/75 (5%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 S E+ ++LF I + + L N + + + + + D +G + Sbjct: 79 SPEEVLKAFQLFDLDKKGKISFANLKEV---AKLLGENPGDDVLQEMIAEA-DEDGDGEV 134 Query: 103 GFEEFARALSVFHPN 117 FEEF + Sbjct: 135 SFEEFKSVMMQMRGK 149 >2E6W-A nrPDB Length = 100 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 47/91 (51%), Gaps = 4/91 (4%) Query: 118 APIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI----IDKTFE 173 + +K+ ++F LYD+ + G+I ++E+ ++ + G + + ED +++ FE Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 174 EADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 + D DG + EE+ + +++ +M L Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIMSSMQL 95 >3KF9-A nrPDB Length = 149 Score = 102 bits (255), Expect = 9e-23, Method: Composition-based stats. Identities = 38/157 (24%), Positives = 76/157 (48%), Gaps = 16/157 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T EI ++LF S G I+ +E ++A+ K+ + D+ D Sbjct: 3 TEEQKQEIREAFDLFDTDGS-----GTIDAKELKVAMRALGFEPKKEEIKKMIADI-DKD 56 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 +G + FEEF + ++ ++I +F+L+D + G I + +K++ E G Sbjct: 57 GSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAK----ELGE 112 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 N+ D ++++ID EAD DG++++EE+ ++ + Sbjct: 113 NMTDEELQEMID----EADRDGDGEVNEEEFFRIMKK 145 >5D43-A nrPDB Length = 178 Score = 99.0 bits (245), Expect = 1e-21, Method: Composition-based stats. Identities = 38/173 (21%), Positives = 80/173 (46%), Gaps = 21/173 (12%) Query: 24 YKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNK 81 YK+ G PEL E+ ++LF S G I+ +E ++A+ Sbjct: 15 YKRKVG-PKPELTEDQ----KQEVREAFDLFDSDGS-----GTIDVKELKVAMRALGFEP 64 Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 ++ + ++ D + G + F +F ++ ++I +F+L+D + G I Sbjct: 65 RKEEMKKMISEV-DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 Query: 142 QEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + +K++ E G +L D ++++ID EAD DG++++EE+ ++ + Sbjct: 124 KNLKRVAN----ELGESLTDEELQEMID----EADRDGDGEVNEEEFLKIMKK 168 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 8/79 (10%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 ++ +F L+D G I+ +E+K + A L ++ + K E D Sbjct: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA--------LGFEPRKEEMKKMISEVD 77 Query: 177 TKHDGKIDKEEWRSLVLRH 195 + GKI ++ +++ + Sbjct: 78 KEATGKISFNDFLAVMTQK 96 >3QRX-A nrPDB Length = 169 Score = 97.8 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 35/157 (22%), Positives = 73/157 (46%), Gaps = 16/157 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T EI ++LF S G I+ +E ++A+ K+ + ++ D Sbjct: 23 TEEQKQEIREAFDLFDTDGS-----GTIDAKELKVAMRALGFEPKKEEIKKMISEI-DKD 76 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 +G + FEEF ++ ++I +F+L+D G I ++++++ E G Sbjct: 77 GSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAK----ELGE 132 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 NL + ++++I EAD D +ID++E+ ++ + Sbjct: 133 NLTEEELQEMI----AEADRNDDNEIDEDEFIRIMKK 165 >2GGM-A nrPDB Length = 172 Score = 97.4 bits (241), Expect = 4e-21, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 74/166 (44%), Gaps = 20/166 (12%) Query: 31 GDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFAD 88 PEL EI ++LF G I+ +E ++A+ K+ Sbjct: 21 PKPELTEEQ----KQEIREAFDLFDADG-----TGTIDVKELKVAMRALGFEPKKEEIKK 71 Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 + ++ D + G + F +F ++ ++I +F+L+D + G I + +K++ Sbjct: 72 MISEI-DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVA 130 Query: 149 VATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 E G NL D ++++ID EAD DG++ ++E+ ++ + Sbjct: 131 K----ELGENLTDEELQEMID----EADRDGDGEVSEQEFLRIMKK 168 >2LMV-A nrPDB Length = 148 Score = 93.6 bits (231), Expect = 6e-20, Method: Composition-based stats. Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + F K G I E + N E+ D + + + Sbjct: 5 TEEQIAEFKDAFVQFDKEG-----TGKIATRELGTLMRTLGQNPTEAELQDLIAEA-ENN 58 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 +NG L F EF ++ ++++ +F+++D GFI E++ +++ Sbjct: 59 NNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMI-------- 110 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 NL + V ++ ID+ EAD DG I+ EE+ ++ + Sbjct: 111 NLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMISQK 148 >2OBH-A nrPDB Length = 143 Score = 92.4 bits (228), Expect = 1e-19, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 72/157 (45%), Gaps = 16/157 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T EI ++LF G I+ +E ++A+ K+ + ++ D + Sbjct: 1 TEEQKQEIREAFDLFDADG-----TGTIDVKELKVAMRALGFEPKKEEIKKMISEI-DKE 54 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 G + F +F ++ ++I +F+L+D + G I + +K++ E G Sbjct: 55 GTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAK----ELGE 110 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 NL D ++++ID EAD DG++ ++E+ ++ + Sbjct: 111 NLTDEELQEMID----EADRDGDGEVSEQEFLRIMKK 143 >2LHI-A nrPDB Length = 176 Score = 89.3 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 67/157 (42%), Gaps = 17/157 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K ++G I+ E + + E+ D + ++ D Sbjct: 6 TEEQIAEFKEAFALFDKD-----NNGSISSSELATVMRSLGLSPSEAEVNDLMNEI-DVD 59 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 N + F EF +S + + ++ +F+++D G I E+K ++ + Sbjct: 60 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI------ 113 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + + +D E + G+I+ +++ +L+ + Sbjct: 114 --GEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 147 >4DS7-A nrPDB Length = 147 Score = 87.4 bits (215), Expect = 5e-18, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 67/157 (42%), Gaps = 17/157 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K + G I+ E + + E+ AD + ++ D Sbjct: 6 TEEQIAEFKEAFALFDKD-----NSGSISASELATVMRSLGLSPSEAEVADLMNEI-DVD 59 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 N + F EF +S + ++ +F+++D G I E+K ++ + Sbjct: 60 GNHAIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI------ 113 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + + +D+ E + G+I+ +++ +L+ + Sbjct: 114 --GEKLTDAEVDEMLREV-SDGSGEINIKQFAALLSK 147 >1LKJ-A nrPDB Length = 146 Score = 84.7 bits (208), Expect = 3e-17, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 67/157 (42%), Gaps = 17/157 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K ++G I+ E + + E+ D + ++ D Sbjct: 5 TEEQIAEFKEAFALFDKD-----NNGSISSSELATVMRSLGLSPSEAEVNDLMNEI-DVD 58 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 N + F EF +S + + ++ +F+++D G I E+K ++ + Sbjct: 59 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI------ 112 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + + +D E + G+I+ +++ +L+ + Sbjct: 113 --GEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 146 >1TOP-A nrPDB Length = 162 Score = 84.3 bits (207), Expect = 4e-17, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 70/154 (45%), Gaps = 19/154 (12%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E +A +++F G I+ +E + N + D + + D +G Sbjct: 19 IAEFKAAFDMFDADG-----GGDISTKELGTVMRMLGQNPTKEEL-DAIIEEVDEDGSGT 72 Query: 102 LGFEEFARALSVFHP---NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 + FEEF + ++++ F+++D GFI+ +E+ +++ A Sbjct: 73 IDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRA-------- 124 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + V E+ I+ +++D +DG+ID +E+ ++ Sbjct: 125 TGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 31/72 (43%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F ++D G I +E+ ++ L ++ +D EE D G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRM--------LGQNPTKEELDAIIEEVDEDGSGT 72 Query: 183 IDKEEWRSLVLR 194 ID EE+ +++R Sbjct: 73 IDFEEFLVMMVR 84 >2TN4-A nrPDB Length = 159 Score = 83.9 bits (206), Expect = 5e-17, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 68/154 (44%), Gaps = 19/154 (12%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E +A +++F G I+ +E + + D + + D +G Sbjct: 16 IAEFKAAFDMFDADG-----GGDISVKELGTVMRMLGQTPTKEEL-DAIIEEVDEDGSGT 69 Query: 102 LGFEEFARALSVFHP---NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 + FEEF + ++++ F+++D G+I+ +E+ ++ A+ Sbjct: 70 IDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRAS------- 122 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + V ++ I+ ++ D +DG+ID +E+ ++ Sbjct: 123 -GEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F ++D G I +E+ ++ L T ++ +D EE D G Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMRM--------LGQTPTKEELDAIIEEVDEDGSGT 69 Query: 183 IDKEEWRSLVLR 194 ID EE+ +++R Sbjct: 70 IDFEEFLVMMVR 81 Score = 32.3 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 8/71 (11%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK--ESLFADRVFDLFDTKHNG 100 S E+ L+ +F + DG I+ EE +F+ + + + + D ++G Sbjct: 91 SEEELAELFRIFDR-----NADGYIDAEELA-EIFRASGEHVTDEEIESLMKDGDKNNDG 144 Query: 101 ILGFEEFARAL 111 + F+EF + + Sbjct: 145 RIDFDEFLKMM 155 >1DTL-A nrPDB Length = 161 Score = 82.4 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 73/159 (45%), Gaps = 18/159 (11%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTK 97 T +E +A +++F +DG I+ +E + + N + + ++ D Sbjct: 13 TEEQKNEFKAAFDIFV----LGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV-DED 67 Query: 98 HNGILGFEEFARALSVFH---PNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 +G + F+EF + ++++ F+++D G+I+ +E+K M+ A Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA---- 123 Query: 155 SGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 +T+ ED I++ ++ D +DG+ID +E+ + Sbjct: 124 ----TGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 40.4 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 38/85 (44%), Gaps = 9/85 (10%) Query: 112 SVFHPNAPIDDKIHFSFQLYDLK-QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK 170 +V ++ +F ++ L + G I +E+ +++ G N ++++ID Sbjct: 8 AVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMR----MLGQNPTPEELQEMID- 62 Query: 171 TFEEADTKHDGKIDKEEWRSLVLRH 195 E D G +D +E+ +++R Sbjct: 63 ---EVDEDGSGTVDFDEFLVMMVRS 84 >3K21-A nrPDB Length = 191 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFE 105 ++E L F + G I KE+ + L K K D + D D+ +G + + Sbjct: 50 DVEKLKSTFLVLDEDG--KGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYT 107 Query: 106 EFARALSVFHPNAPIDDKIHF-SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 EF A + K+ + +F+++D+ G I E+ ++ + + +D Sbjct: 108 EFIAA---ALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQRDV-- 162 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + + + + D +DGKID E+ ++ Sbjct: 163 -NRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 36/81 (44%), Gaps = 9/81 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +K+ +F + D +G+I ++++K+ + + N D ++ D+ G Sbjct: 52 EKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNF---------DLLLDQIDSDGSG 102 Query: 182 KIDKEEWRSLVLRHPSLLKNM 202 KID E+ + L L K + Sbjct: 103 KIDYTEFIAAALDRKQLSKKL 123 Score = 33.1 bits (74), Expect = 0.094, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 30/77 (38%), Gaps = 11/77 (14%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFA------DRVFDLFDT 96 S I + +F +DG I E L+ NKK ++ R+ D Sbjct: 120 SKKLIYCAFRVFDVD-----NDGEITTAELAHILYNGNKKGNITQRDVNRVKRMIRDVDK 174 Query: 97 KHNGILGFEEFARALSV 113 ++G + F EF+ + + Sbjct: 175 NNDGKIDFHEFSEMMKL 191 >4RGJ-A nrPDB Length = 520 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 71/164 (43%), Gaps = 25/164 (15%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLA---LFKTNKKESL---------FADRV 90 ++ E + L ++FKK+ DG +++ E + L K +++ D++ Sbjct: 366 TIDETKELTKIFKKMDKNG--DGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQI 423 Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 + D NG + + EF +S+ +++ +F+L+D G I E+ Q+ Sbjct: 424 LNSIDLDQNGYIEYSEFLT-VSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFGL 482 Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + S +E D +DG+ID +E+R ++++ Sbjct: 483 SDVSSECW----------KTVLKEVDQNNDGEIDFKEFRDMLVK 516 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 35/98 (35%), Gaps = 3/98 (3%) Query: 111 LSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD---TVIEDI 167 + ++ F+ D G ++R E+ L G + D IE Sbjct: 360 MGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYE 419 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 +D+ D +G I+ E+ ++ + LL L+ Sbjct: 420 VDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERLE 457 Score = 34.6 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 19/49 (38%) Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ A L G L + K F++ D DG++D+ E Sbjct: 351 KLAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKE 399 >3HZT-A nrPDB Length = 467 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 81/199 (40%), Gaps = 28/199 (14%) Query: 9 KHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSV-SEIEALYELFKKISSAVIDDGLI 67 KH T LG ++ ++ S L +L + + E + L ++F+++ + DG + Sbjct: 276 KHALTGALG--NMKKFQSSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNG--DGQL 331 Query: 68 NKEEF-----QLALFK-------TNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFH 115 +++E +L +K + + D + D NG + + EF Sbjct: 332 DRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQ 391 Query: 116 PNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA 175 +++ +FQ +D G I +E+ ++ V ++ + +E Sbjct: 392 LL-LSRERLLAAFQQFDSDGSGKITNEELGRLFGV----------TEVDDETWHQVLQEC 440 Query: 176 DTKHDGKIDKEEWRSLVLR 194 D +DG++D EE+ ++ + Sbjct: 441 DKNNDGEVDFEEFVEMMQK 459 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 40/96 (41%), Gaps = 5/96 (5%) Query: 109 RALSVFHPNAPIDD--KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD---TV 163 L + +++ ++ F+ D G ++R+E+ + + G + D + Sbjct: 299 AMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQ 358 Query: 164 IEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 IE +D + D +G I+ E+ ++ + LL Sbjct: 359 IEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLL 394 >4JWQ-A nrPDB Length = 199 Score = 78.6 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 65/149 (43%), Gaps = 9/149 (6%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFE 105 +++ L +F + G I K + + L + K D + D D+ +G + + Sbjct: 56 DLQQLKTVFLYLDEDG--KGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYT 113 Query: 106 EFARALSVFHPNAPIDDKIHF-SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 EF L+ + K+ + +F+++D+ G I E+ ++ + + KD Sbjct: 114 EF---LAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDV-- 168 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + + K +E D +DGKID E+ ++ Sbjct: 169 -NQVKKMIQEVDKNNDGKIDFYEFCEMMK 196 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 30/97 (30%), Gaps = 4/97 (4%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAP 119 G I+ EF A F +FD ++G + E A L + Sbjct: 103 DSDGSGRIDYTEFLAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGS 162 Query: 120 IDDK----IHFSFQLYDLKQQGFIERQEVKQMVVATL 152 I K + Q D G I+ E +M+ Sbjct: 163 ITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMKLKY 199 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++ F D +G I + ++K+ + N + ++ D ++ D+ G Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKKGL--------ENSGLKLPQNF-DVLLDQIDSDGSG 108 Query: 182 KIDKEEWRSLVLRHPSLLKNM 202 +ID E+ + L L K + Sbjct: 109 RIDYTEFLAAALDRKHLSKKL 129 Score = 30.4 bits (67), Expect = 0.59, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 29/78 (37%), Gaps = 11/78 (14%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDL------FDT 96 S I + +F +DG I E L+ NKK S+ V + D Sbjct: 126 SKKLIYCAFRVFDVD-----NDGEITTAELAHILYNGNKKGSITQKDVNQVKKMIQEVDK 180 Query: 97 KHNGILGFEEFARALSVF 114 ++G + F EF + + Sbjct: 181 NNDGKIDFYEFCEMMKLK 198 >2KN2-A nrPDB Length = 92 Score = 77.4 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 46/79 (58%), Gaps = 8/79 (10%) Query: 115 HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEE 174 H + ++++ +F+++D Q G+I E++ +++ NL + + ++ +++ +E Sbjct: 2 HMDTDAEEELKEAFKVFDKDQNGYISASELRHVMI--------NLGEKLTDEEVEQMIKE 53 Query: 175 ADTKHDGKIDKEEWRSLVL 193 AD DG+++ EE+ +++ Sbjct: 54 ADLDGDGQVNYEEFVKMMM 72 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGIL 102 E++ +++F K +G I+ E + + +K +++ D +G + Sbjct: 8 EEELKEAFKVFDKD-----QNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQV 62 Query: 103 GFEEFARAL 111 +EEF + + Sbjct: 63 NYEEFVKMM 71 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 27/73 (36%), Gaps = 1/73 (1%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 + F +FD NG + E R + + D+++ + DL G + Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASE-LRHVMINLGEKLTDEEVEQMIKEADLDGDGQV 62 Query: 140 ERQEVKQMVVATL 152 +E +M++ Sbjct: 63 NYEEFVKMMMTVR 75 >5JN2-A nrPDB Length = 525 Score = 76.6 bits (187), Expect = 8e-15, Method: Composition-based stats. Identities = 31/164 (18%), Positives = 69/164 (42%), Gaps = 25/164 (15%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF----QLALFKTNKKESLF--------ADRV 90 S E + L +F K+ DG +++ E + + + S+ D+V Sbjct: 371 SQDETKELTAIFHKMDKNG--DGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQV 428 Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 D D NG + + EF +++ +++ +F+++D G I E+ + Sbjct: 429 LDAVDFDKNGYIEYSEFVT-VAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIF-- 485 Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 G++ D+ + E D +DG++D +E++ ++L+ Sbjct: 486 -----GVSDVDSETWKSV---LSEVDKNNDGEVDFDEFQQMLLK 521 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 36/92 (39%), Gaps = 3/92 (3%) Query: 111 LSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM---NLKDTVIEDI 167 + + ++ F D G ++R E+ + + G L + +E Sbjct: 365 MGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHE 424 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 +D+ + D +G I+ E+ ++ + +LL Sbjct: 425 VDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLL 456 Score = 35.4 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 17/49 (34%) Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ A L G L + F + D DG++D+ E Sbjct: 356 KLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKE 404 >3O4Y-A nrPDB Length = 196 Score = 76.2 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 61/149 (40%), Gaps = 9/149 (6%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFE 105 +++ L F + G I K + + L ++ D + D D+ +G + + Sbjct: 53 DVQKLKAAFLHLDE--EGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYT 110 Query: 106 EFARALSVFHPNAPIDDKIHF-SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 EF L+ + K+ + +F+++D+ G I E+ ++ + +D Sbjct: 111 EF---LAAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRGNITERDV-- 165 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + + K E D DGKID E+ ++ Sbjct: 166 -NQVKKMIREVDKNGDGKIDFYEFSEMMK 193 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 34/97 (35%), Gaps = 4/97 (4%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAP 119 G I+ EF A + F +FD ++G + E A L + Sbjct: 100 DSDGSGNIDYTEFLAAAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRGN 159 Query: 120 IDDK----IHFSFQLYDLKQQGFIERQEVKQMVVATL 152 I ++ + + D G I+ E +M+ TL Sbjct: 160 ITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMKLTL 196 Score = 34.6 bits (78), Expect = 0.030, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 32/81 (39%), Gaps = 9/81 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 K+ +F D + +G I + ++++ + + N D ++ D+ G Sbjct: 55 QKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNF---------DLLLDQIDSDGSG 105 Query: 182 KIDKEEWRSLVLRHPSLLKNM 202 ID E+ + + L K + Sbjct: 106 NIDYTEFLAAAIDRRQLSKKL 126 >2HF5-A nrPDB Length = 68 Score = 76.2 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 84 SLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 + D + ++ D NG + F EF ++ + +++I +F+++D G+I E Sbjct: 1 AELQDMINEV-DADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAE 59 Query: 144 VKQMVV 149 ++ ++ Sbjct: 60 LRHVMT 65 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 24/61 (39%), Gaps = 7/61 (11%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 D G I+ E M+ +KDT E+ I + F D +G I E R + Sbjct: 11 DADGNGTIDFPEFLTMMA-------RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 63 Query: 192 V 192 + Sbjct: 64 M 64 >1FW4-A nrPDB Length = 71 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 41/76 (53%), Gaps = 8/76 (10%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 + +++I +F+++D G+I E++ ++ NL + + ++ +D+ EAD Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVM--------TNLGEKLTDEEVDEMIREAD 52 Query: 177 TKHDGKIDKEEWRSLV 192 DG+++ EE+ ++ Sbjct: 53 IDGDGQVNYEEFVQMM 68 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S EI + +F K +G I+ E + + +K D + D +G Sbjct: 4 SEEEIREAFRVFDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 58 Query: 102 LGFEEFARALSVF 114 + +EEF + ++ Sbjct: 59 VNYEEFVQMMTAK 71 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 1/72 (1%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 + F +FD NG + E R + D+++ + D+ G + Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAE-LRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 59 Query: 140 ERQEVKQMVVAT 151 +E QM+ A Sbjct: 60 NYEEFVQMMTAK 71 >2LAP-A nrPDB Length = 167 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 56/157 (35%), Gaps = 19/157 (12%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 + E+ + F K DG IN + + E + + + G Sbjct: 24 IEELREAFREFDKD-----KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGH 77 Query: 102 LGFEEFARALSVFHPNAPID----DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 + F++F + D ++ +F+ +D G I E+++ A G Sbjct: 78 VDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELRE---AMRKLLGH 134 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + IE+ + D DG++D EE+ ++ R Sbjct: 135 QVGHRDIEE----IIRDVDLNGDGRVDFEEFVRMMSR 167 >3LIJ-A nrPDB Length = 494 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 60/161 (37%), Gaps = 22/161 (13%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF---------QLALFKTNKKESLFADRVFDL 93 S E + L ++F+ I DG ++++E + + D + Sbjct: 341 SQEETKELTDIFRHIDKNG--DGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGA 398 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 D NG + + EF +++ + DK+ +FQ +D G I E+ + Sbjct: 399 ADFDRNGYIDYSEFVT-VAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGL--- 454 Query: 154 ESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 D + + D+ +DG +D EE+ ++ + Sbjct: 455 -------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 488 Score = 50.1 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 36/95 (37%) Query: 111 LSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK 170 ++ + ++ F+ D G ++RQE+ E IE +D Sbjct: 335 MASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDA 394 Query: 171 TFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 AD +G ID E+ ++ + SLL L+ Sbjct: 395 ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLE 429 Score = 33.9 bits (76), Expect = 0.064, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 18/45 (40%), Gaps = 1/45 (2%) Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 A L + +++ D F D DG++D++E + Sbjct: 331 ALLYMASKLTSQEETKELTD-IFRHIDKNGDGQLDRQELIDGYSK 374 >2LHH-A nrPDB Length = 128 Score = 75.1 bits (183), Expect = 2e-14, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 54/128 (42%), Gaps = 12/128 (9%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K ++G I+ E + + E+ D + ++ D Sbjct: 5 TEEQIAEFKEAFALFDKD-----NNGSISSSELATVMRSLGLSPSEAEVNDLMNEI-DVD 58 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 N + F EF +S + + ++ +F+++D G I E+K ++ + G Sbjct: 59 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI----GE 114 Query: 158 NLKDTVIE 165 L D +E Sbjct: 115 KLTDAELE 122 Score = 47.0 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 30/72 (41%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I E+ ++ + L + E ++ E D + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRS--------LGLSPSEAEVNDLMNEIDVDGNHQ 62 Query: 183 IDKEEWRSLVLR 194 I+ E+ +L+ R Sbjct: 63 IEFSEFLALMSR 74 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 42/114 (36%), Gaps = 10/114 (8%) Query: 80 NKKESLFADR--VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQG 137 N E A+ F LFD +NG + E A + + P + +++ D+ Sbjct: 3 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLS-PSEAEVNDLMNEIDVDGNH 61 Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 IE E ++ LK E + + F+ D DG I E + + Sbjct: 62 QIEFSEFLALMS-------RQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHV 108 >2KZ2-A nrPDB Length = 94 Score = 74.7 bits (182), Expect = 3e-14, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 40/79 (50%), Gaps = 8/79 (10%) Query: 114 FHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFE 173 + +++I +F++ D G+I E++ ++ NL + + ++ +D+ Sbjct: 21 LMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVM--------TNLGEKLTDEEVDEMIR 72 Query: 174 EADTKHDGKIDKEEWRSLV 192 EAD DG+++ EE+ ++ Sbjct: 73 EADIDGDGQVNYEEFVQMM 91 Score = 35.4 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 26/82 (31%), Gaps = 1/82 (1%) Query: 70 EEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQ 129 E + F + D NG + E R + D+++ + Sbjct: 14 ENLYFQSLMKDTDSEEEIREAFRVEDKDGNGYISAAE-LRHVMTNLGEKLTDEEVDEMIR 72 Query: 130 LYDLKQQGFIERQEVKQMVVAT 151 D+ G + +E QM+ A Sbjct: 73 EADIDGDGQVNYEEFVQMMTAK 94 Score = 35.4 bits (80), Expect = 0.023, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFD 92 + L +DT S EI + + K +G I+ E + + +K D + Sbjct: 19 QSLMKDTD-SEEEIREAFRVEDKDG-----NGYISAAELRHVMTNLGEKLTDEEVDEMIR 72 Query: 93 LFDTKHNGILGFEEFARALSVF 114 D +G + +EEF + ++ Sbjct: 73 EADIDGDGQVNYEEFVQMMTAK 94 >4YZB-A nrPDB Length = 491 Score = 74.3 bits (181), Expect = 4e-14, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 68/164 (41%), Gaps = 25/164 (15%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF--QLALFKTNKKESLFA----------DRV 90 + E L ++F+++ DG ++K+E K E + A ++V Sbjct: 334 TNEETVELNKIFQRMDKNG--DGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQV 391 Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 D D NG + + EF +++ ++ +F ++D G I E+ + Sbjct: 392 LDAVDFDKNGFIEYSEFVT-VAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIF-- 448 Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 G++ D+ + E D +DG++D EE+R ++L+ Sbjct: 449 -----GVSEVDSETWRRV---LAEVDRNNDGEVDFEEFRQMLLK 484 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK---DTVIEDIIDKTFEEADTKH 179 +++ FQ D G +++QE+ + V + G ++ + IE +++ + D Sbjct: 340 ELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDK 399 Query: 180 DGKIDKEEWRSLVLRHPSLLKNMTLQ 205 +G I+ E+ ++ + +LL L+ Sbjct: 400 NGFIEYSEFVTVAMDRKTLLSRQRLE 425 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%) Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 ++ A L G L ++K F+ D DG++DK+E Sbjct: 319 KLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEG 364 >2RO9-A nrPDB Length = 69 Score = 73.9 bits (180), Expect = 5e-14, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 42/77 (54%), Gaps = 8/77 (10%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 ++++ +F+++D Q GFI E++ ++ NL + + ++ +D+ EAD Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVM--------TNLGEKLTDEEVDEMIREADVD 52 Query: 179 HDGKIDKEEWRSLVLRH 195 DG+I+ EE+ +++ Sbjct: 53 GDGQINYEEFVKVMMAK 69 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F +FD NG + E R + D+++ + D+ G I +E ++++A Sbjct: 10 FRVFDKDQNGFISAAE-LRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 68 Query: 151 T 151 Sbjct: 69 K 69 Score = 35.8 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 29/70 (41%), Gaps = 6/70 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S E++ + +F K +G I+ E + + +K D + D +G Sbjct: 2 SEEELKEAFRVFDKD-----QNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQ 56 Query: 102 LGFEEFARAL 111 + +EEF + + Sbjct: 57 INYEEFVKVM 66 >4MVF-A nrPDB Length = 506 Score = 73.5 bits (179), Expect = 7e-14, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 65/150 (43%), Gaps = 10/150 (6%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKT-NKKESLFADRVFDLFDTKHNGILGF 104 EI L +F + V + G ++ +E L K +K +V D+ +G + + Sbjct: 358 EINNLRNIFIALD--VDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHY 415 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 +F A + + F+ +D+ G I +E+K++ ++++ +I Sbjct: 416 TDFLAATIDKQTYLKKEVCLI-PFKFFDIDGNGKISVEELKRIF------GRDDIENPLI 468 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + ID +E D DG+ID E+ ++ + Sbjct: 469 DKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 498 Score = 34.3 bits (77), Expect = 0.042, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 36/106 (33%), Gaps = 9/106 (8%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 +F D ++G L +E L D IH + D G I + + Sbjct: 365 IFIALDVDNSGTLSSQEILDGLKKIGYQKIPPD-IHQVLRDIDSNASGQIHYTDFLAATI 423 Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 + + +++ F+ D +GKI EE + + R Sbjct: 424 DK--------QTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRD 461 Score = 30.0 bits (66), Expect = 0.78, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 27/80 (33%), Gaps = 8/80 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + + F D+ G + QE+ + + I + + D+ G Sbjct: 360 NNLRNIFIALDVDNSGTLSSQEILDGLKKI---GYQKIPPD-----IHQVLRDIDSNASG 411 Query: 182 KIDKEEWRSLVLRHPSLLKN 201 +I ++ + + + LK Sbjct: 412 QIHYTDFLAATIDKQTYLKK 431 >3Q5I-A nrPDB Length = 504 Score = 73.2 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 68/163 (41%), Gaps = 26/163 (15%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF--QLALFKTNKKE-------SLFADRVFDL 93 ++ E + L ++FKK+ DG ++K+E + + K E D + Sbjct: 350 TLEERKELTDIFKKLDKNG--DGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKE 407 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPI--DDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 D NG + + EF SV + ++++ +F L+D + G I ++E+ + Sbjct: 408 VDFDKNGYIEYSEFI---SVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFGL- 463 Query: 152 LAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ E + EAD D ID +E+ S++ + Sbjct: 464 ---------TSISEKTWNDVLGEADQNKDNMIDFDEFVSMMHK 497 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 34/85 (40%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 ++ F+ D G ++++E+ + + +E+ +D +E D + Sbjct: 354 RKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKN 413 Query: 181 GKIDKEEWRSLVLRHPSLLKNMTLQ 205 G I+ E+ S+ + L L+ Sbjct: 414 GYIEYSEFISVCMDKQILFSEERLR 438 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 35/100 (35%), Gaps = 10/100 (10%) Query: 24 YKQSGGLGDPELLA----RDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKT 79 + ++G + E ++ + +FS + + LF G I KEE LF Sbjct: 410 FDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTD-----KSGKITKEELA-NLFGL 463 Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAP 119 + V D + ++ F+EF + + Sbjct: 464 TSISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKICDHKT 503 Score = 33.9 bits (76), Expect = 0.063, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 ++ A + G L + F++ D DG++DK+E Sbjct: 335 KLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEG 380 >2ROB-A nrPDB Length = 70 Score = 72.8 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 44/75 (58%), Gaps = 8/75 (10%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 ++++ +F+++D Q G+I E++ +++ NL + + ++ +++ +EAD Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMI--------NLGEKLTDEEVEQMIKEADLD 52 Query: 179 HDGKIDKEEWRSLVL 193 DG+++ EE+ +++ Sbjct: 53 GDGQVNYEEFVKMMM 67 Score = 35.8 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGIL 102 E++ +++F K +G I+ E + + +K +++ D +G + Sbjct: 3 EEELKEAFKVFDKD-----QNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQV 57 Query: 103 GFEEFARAL 111 +EEF + + Sbjct: 58 NYEEFVKMM 66 Score = 35.4 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 26/71 (36%), Gaps = 1/71 (1%) Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 F +FD NG + E R + + D+++ + DL G + Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASE-LRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNY 59 Query: 142 QEVKQMVVATL 152 +E +M++ Sbjct: 60 EEFVKMMMTVR 70 >1S6I-A nrPDB Length = 188 Score = 72.4 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 18/157 (11%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKH 98 S EI L ELFK I + G I +E + L + ES D + D D Sbjct: 3 RLSEEEIGGLKELFKMID--TDNSGTITFDELKDGLKRVGSELMESEIKDLM-DAADIDK 59 Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 +G + + EF A +V ++ + +F +D G+I E++Q Sbjct: 60 SGTIDYGEFIAA-TVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACK--------- 109 Query: 159 LKDTVIEDI-IDKTFEEADTKHDGKIDKEEWRSLVLR 194 D ++DI ID +E D +DG+ID E+ +++ + Sbjct: 110 --DFGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 36/97 (37%), Gaps = 10/97 (10%) Query: 26 QSGGLGDPELLARDTVFSVSEIEA----LYELFKKISSAVIDDGLINKEEFQLALFKTNK 81 +SG + E +A + E E + F K S G I +E Q A K Sbjct: 59 KSGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGS-----GYITLDEIQQAC-KDFG 112 Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 + + D + D ++G + + EFA + N Sbjct: 113 LDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRKRKGNG 149 >3KHE-A nrPDB Length = 191 Score = 72.0 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 77/199 (38%), Gaps = 28/199 (14%) Query: 9 KHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSV-SEIEALYELFKKISSAVIDDGLI 67 KH T LG ++ ++ S L +L + + E + L ++F+++ + DG + Sbjct: 2 KHALTGALG--NMKKFQSSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNG--DGQL 57 Query: 68 NKEEF------------QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFH 115 +++E + + D + D NG + + EF Sbjct: 58 DRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQ 117 Query: 116 PNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA 175 +++ +FQ +D G I +E+ ++ V ++ + +E Sbjct: 118 LL-LSRERLLAAFQQFDSDGSGKITNEELGRLFGV----------TEVDDETWHQVLQEC 166 Query: 176 DTKHDGKIDKEEWRSLVLR 194 D +DG++D EE+ ++ + Sbjct: 167 DKNNDGEVDFEEFVEMMQK 185 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 40/96 (41%), Gaps = 5/96 (5%) Query: 109 RALSVFHPNAPIDD--KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD---TV 163 L + +++ ++ F+ D G ++R+E+ + + G + D + Sbjct: 25 AMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQ 84 Query: 164 IEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 IE +D + D +G I+ E+ ++ + LL Sbjct: 85 IEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLL 120 >3FWC-A nrPDB Length = 161 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 70/163 (42%), Gaps = 20/163 (12%) Query: 32 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADR 89 + ELL EI + LF +DG ++ E ++A+ + D Sbjct: 14 NSELLEEQ----KQEIYEAFSLFDM-----NNDGFLDYHELKVAMKALGFELPKREILD- 63 Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + D +D++ ++ +++F + D+I +FQL+D G I + ++++ Sbjct: 64 LIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAK 123 Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 L +T+ ++ + EE D DG+I++ E+ ++ Sbjct: 124 --------ELGETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 33/102 (32%), Gaps = 29/102 (28%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVAT-----------------------------L 152 +I+ +F L+D+ GF++ E+K + A Sbjct: 23 QEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFY 82 Query: 153 AESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 G + D I + F+ D H GKI + R + Sbjct: 83 IVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKE 124 >2M5E-A nrPDB Length = 73 Score = 71.6 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 38/78 (48%), Gaps = 8/78 (10%) Query: 115 HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEE 174 ++++ +F+++D G I E++ ++ NL + + +D +D+ E Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVM--------TNLGEKLTDDEVDEMIRE 52 Query: 175 ADTKHDGKIDKEEWRSLV 192 AD DG I+ EE+ ++ Sbjct: 53 ADIDGDGHINYEEFVRMM 70 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 7/64 (10%) Query: 91 FDLFDTKHNGILGFEEF---ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 F +FD NG++ E L + +D+ I + D+ G I +E +M Sbjct: 14 FKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREA----DIDGDGHINYEEFVRM 69 Query: 148 VVAT 151 +V+ Sbjct: 70 MVSK 73 Score = 35.4 bits (80), Expect = 0.018, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGI 101 S E+ +++F + +GLI+ E + + +K D + D +G Sbjct: 6 SEEELIEAFKVFDRDG-----NGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGH 60 Query: 102 LGFEEFARAL 111 + +EEF R + Sbjct: 61 INYEEFVRMM 70 >1M39-A nrPDB Length = 89 Score = 71.2 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 48/93 (51%), Gaps = 8/93 (8%) Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F +F ++ ++I +F+L+D + G I + +K++ E G NL D Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAK----ELGENLTD 56 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++++ID EAD DG++ ++E+ ++ + Sbjct: 57 EELQEMID----EADRDGDGEVSEQEFLRIMKK 85 Score = 30.0 bits (66), Expect = 0.90, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 F LFD G + F+ + ++ D+++ D G + QE +++ Sbjct: 27 FKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMK 84 Score = 28.1 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 27/73 (36%), Gaps = 4/73 (5%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 + EI ++LF + I + + +L N + + + + D +G + Sbjct: 19 TKEEILKAFKLFDDDETGKISFKNLKRVAKEL---GENLTDEELQEMIDEA-DRDGDGEV 74 Query: 103 GFEEFARALSVFH 115 +EF R + Sbjct: 75 SEQEFLRIMKKTS 87 >3NCG-A nrPDB Length = 486 Score = 71.2 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 27/166 (16%), Positives = 71/166 (42%), Gaps = 26/166 (15%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKT------------NKKESLFADRV 90 ++ E + L E+F+K+ + +DG+++++E + + S D++ Sbjct: 326 TLDETKQLTEIFRKLDTN--NDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQI 383 Query: 91 FDLF---DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 L D +G + + EF + ++ +++ +F+++D G I +E+ ++ Sbjct: 384 DSLMPLLDMDGSGSIEYSEFIAS-AIDRTILLSRERMERAFKMFDKDGSGKISTKELFKL 442 Query: 148 VVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 +E++ + E+ D DG++D E+ ++ Sbjct: 443 FS-------QADSSIQMEEL-ESIIEQVDNNKDGEVDFNEFVEMLQ 480 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 48/131 (36%), Gaps = 22/131 (16%) Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFH-------------PNAPIDDKIHFSF 128 E+ +F DT ++G+L +E R F + I+D+I Sbjct: 328 DETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLM 387 Query: 129 QLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE- 187 L D+ G IE E S ++ + + +++ F+ D GKI +E Sbjct: 388 PLLDMDGSGSIEYSE--------FIASAIDRTILLSRERMERAFKMFDKDGSGKISTKEL 439 Query: 188 WRSLVLRHPSL 198 ++ S+ Sbjct: 440 FKLFSQADSSI 450 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 11/109 (10%) Query: 14 SVLGCFDLDLYKQSGGLGDPELLA----RDTVFSVSEIEALYELFKKISSAVIDDGLINK 69 S++ D+D SG + E +A R + S +E +++F K S I K Sbjct: 385 SLMPLLDMD---GSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKIS----TK 437 Query: 70 EEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 E F+L + + + + + D +G + F EF L F N Sbjct: 438 ELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQNFVRNE 486 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 34/95 (35%), Gaps = 6/95 (6%) Query: 111 LSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM------NLKDTVI 164 ++ ++ F+ D G ++R E+ + + G+ + + I Sbjct: 320 MASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTI 379 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 ED ID D G I+ E+ + + LL Sbjct: 380 EDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILL 414 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 20/47 (42%) Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 K++ A L L + + F + DT +DG +D++E Sbjct: 310 KKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRG 356 >3PM8-A nrPDB Length = 197 Score = 70.9 bits (172), Expect = 4e-13, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 65/152 (42%), Gaps = 10/152 (6%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKT-NKKESLFADRVFDLFDTKHNGILGF 104 EI L +F + V + G ++ +E L K +K +V D+ +G + + Sbjct: 55 EINNLRNIFIALD--VDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHY 112 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 +F A + + F+ +D+ G I +E+K++ ++++ +I Sbjct: 113 TDFLAATIDKQTYLKKEVCLI-PFKFFDIDGNGKISVEELKRIF------GRDDIENPLI 165 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + ID +E D DG+ID E+ ++ + Sbjct: 166 DKAIDSLLQEVDLNGDGEIDFHEFMLMMSKKK 197 Score = 28.9 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 27/80 (33%), Gaps = 8/80 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + + F D+ G + QE+ + + I + + D+ G Sbjct: 57 NNLRNIFIALDVDNSGTLSSQEILDGLKKI---GYQKIPPD-----IHQVLRDIDSNASG 108 Query: 182 KIDKEEWRSLVLRHPSLLKN 201 +I ++ + + + LK Sbjct: 109 QIHYTDFLAATIDKQTYLKK 128 >3L19-A nrPDB Length = 214 Score = 70.9 bits (172), Expect = 4e-13, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 60/161 (37%), Gaps = 22/161 (13%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF---------QLALFKTNKKESLFADRVFDL 93 S E + L ++F+ I DG ++++E + + D + Sbjct: 58 SQEETKELTDIFRHIDKNG--DGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGA 115 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 D NG + + EF +++ + DK+ +FQ +D G I E+ + Sbjct: 116 ADFDRNGYIDYSEFVT-VAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFGL--- 171 Query: 154 ESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 D + + D+ +DG +D EE+ ++ + Sbjct: 172 -------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 205 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 36/95 (37%) Query: 111 LSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK 170 ++ + ++ F+ D G ++RQE+ E IE +D Sbjct: 52 MASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDA 111 Query: 171 TFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 AD +G ID E+ ++ + SLL L+ Sbjct: 112 ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLE 146 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 50/112 (44%), Gaps = 13/112 (11%) Query: 14 SVLGCFDLDLYKQSGGLGDPELLA----RDTVFSVSEIEALYELFKKISSAVIDDGLINK 69 ++LG D D ++G + E + R ++ S ++E+ ++ F + +G I+ Sbjct: 111 AILGAADFD---RNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDG-----NGKISV 162 Query: 70 EEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPID 121 +E ++F + ES + D+ ++G + FEEF + + N Sbjct: 163 DELA-SVFGLDHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLCSNNEPQ 213 Score = 31.9 bits (71), Expect = 0.20, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 18/45 (40%), Gaps = 1/45 (2%) Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 A L + +++ D F D DG++D++E + Sbjct: 48 ALLYMASKLTSQEETKELTD-IFRHIDKNGDGQLDRQELIDGYSK 91 >2JNF-A nrPDB Length = 158 Score = 70.5 bits (171), Expect = 6e-13, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 67/159 (42%), Gaps = 16/159 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 + S ++++ L F+ G ++ ++ + L + +S + D FD Sbjct: 5 SKLSSNQVKLLETAFR-DFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQ-LIDEFDPF 62 Query: 98 HNGILGFEEFARALSVFHPNA----PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 NG + F+ F + F + ++ +F+LYD + G+I +++++ Sbjct: 63 GNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILA---- 118 Query: 154 ESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 L +T+ + +D +E D G +D EE+ ++ Sbjct: 119 ----ELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 153 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 37/96 (38%), Gaps = 6/96 (6%) Query: 17 GCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL 76 G D D +K G E + + + E+ + L+ K + I ++ + +L Sbjct: 65 GDIDFDSFKIIGARFLGEEVNPEQM--QQELREAFRLYDKEGNGYISTDVMREILAEL-- 120 Query: 77 FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALS 112 S D + D D +G + FEEF ++ Sbjct: 121 --DETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 >2AAO-A nrPDB Length = 166 Score = 69.7 bits (169), Expect = 9e-13, Method: Composition-based stats. Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 16/154 (10%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNG 100 S EI L E+F I G I EE + L N KES D + D ++G Sbjct: 22 SEEEIAGLKEMFNMID--ADKSGQITFEELKAGLKRVGANLKESEILDLM-QAADVDNSG 78 Query: 101 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK 160 + ++EF A ++ +D + +F +D G+I E++Q E Sbjct: 79 TIDYKEFIAA-TLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFGVE------ 131 Query: 161 DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + I++ + D +DG+ID E+ +++ + Sbjct: 132 ----DVRIEELMRDVDQDNDGRIDYNEFVAMMQK 161 Score = 33.1 bits (74), Expect = 0.099, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 6/75 (8%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILG 103 + A + F K S G I +E Q A + E + + + D ++G + Sbjct: 98 EDHLFAAFTYFDKDGS-----GYITPDELQQAC-EEFGVEDVRIEELMRDVDQDNDGRID 151 Query: 104 FEEFARALSVFHPNA 118 + EF + Sbjct: 152 YNEFVAMMQKGSITG 166 >2M29-A nrPDB Length = 171 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 40/98 (40%), Gaps = 11/98 (11%) Query: 100 GILGFEEFARALSVFHPNAPID----DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 G + FEEF +S ++ +F+ +D + G I E++Q A Sbjct: 79 GFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPAL---- 134 Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 L + + +D+ E D DG ID +E+ ++ Sbjct: 135 ---LGEPLEGTELDEMLREMDLNGDGTIDFDEFVMMLS 169 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 25/71 (35%), Gaps = 7/71 (9%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKE--SLFADRVFDLFDTKHNGI 101 V E+ + F K DG I E + A + D + D +G Sbjct: 104 VRELRIAFREFDKD-----RDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGT 158 Query: 102 LGFEEFARALS 112 + F+EF LS Sbjct: 159 IDFDEFVMMLS 169 >2BL0-C nrPDB Length = 142 Score = 68.5 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 61/151 (40%), Gaps = 17/151 (11%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNGI 101 VSE + +ELF G I KE Q L F + + F + +F+ D NG Sbjct: 5 VSEFKEAFELFDSE-----RTGFITKEGLQTVLKQFGVRVEPAAFNE-MFNEADATGNGK 58 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F EF + +D + +F+ +D + G+I + ++ ++ G LK Sbjct: 59 IQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNL----GDRLKP 114 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + + T E G+I + + + + Sbjct: 115 HEFAEFLGITETEK-----GQIRYDNFINTM 140 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 46/92 (50%), Gaps = 10/92 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F+L+D ++ GFI ++ ++ ++ + G+ ++ ++ F EAD +GK Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLK----QFGVRVEPAAFNEM----FNEADATGNGK 58 Query: 183 IDKEEWRSLVLRHPSLLKNMTLQYLKDITTTF 214 I E+ S++ R + + + L+ TF Sbjct: 59 IQFPEFLSMMGR--RMKQTTSEDILRQAFRTF 88 >3IFK-A nrPDB Length = 90 Score = 66.6 bits (161), Expect = 8e-12, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K DG I +E + N E+ D + ++ D Sbjct: 5 TEEQIAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 58 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQ 129 NG + F EF ++ + +++I +F+ Sbjct: 59 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 62 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 63 IDFPEFLTMMARK 75 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 30/83 (36%), Gaps = 8/83 (9%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F LFD +G + +E + P + ++ D G I+ E M+ Sbjct: 16 FSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA- 73 Query: 151 TLAESGMNLKDTVIEDIIDKTFE 173 +KDT E+ I + F Sbjct: 74 ------RKMKDTDSEEEIREAFR 90 >2LC5-A nrPDB Length = 151 Score = 66.2 bits (160), Expect = 9e-12, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 64/158 (40%), Gaps = 17/158 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T E + ++LF K +D + EE + N + ++ + +D Sbjct: 9 TAEEQQEYKEAFQLFDKD-----NDNKLTAEELGTVMRALGANPTKQKISE-IVKDYDKD 62 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 ++G E F + + + I +F+++D ++ G+I E+K ++ Sbjct: 63 NSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTT------- 115 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 L + + E +D +E + +G I+ +++ L+ Sbjct: 116 -LGEKLTEQEVDDLLKEIGVE-EGLINVDDFVKLITSK 151 >2JNX-A nrPDB Length = 134 Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 53/140 (37%), Gaps = 17/140 (12%) Query: 53 LFKKISSAVIDDGLINKEEFQLALFKTNK-KESLFADRVFDLFDTKHNGILGFEEFARAL 111 LFK++ + DG ++ EE + + K +F D NG + EF + Sbjct: 5 LFKQLDANG--DGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFA 62 Query: 112 SVFHPNAPIDDK--IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID 169 + D+K + ++L D G + ++EV E ++D Sbjct: 63 AAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKF-----------GYEKVVD 111 Query: 170 KTFEEADTKHDGKIDKEEWR 189 + +AD DG I EE+ Sbjct: 112 QI-MKADANGDGYITLEEFL 130 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 24/65 (36%), Gaps = 8/65 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ D G + +EVK V + E ++ F+ D +G+ID E Sbjct: 6 FKQLDANGDGSVSYEEVKAFVSSKR--------PIKNEQLLQLIFKAIDIDGNGEIDLAE 57 Query: 188 WRSLV 192 + Sbjct: 58 FTKFA 62 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 18/41 (43%) Query: 167 IIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYL 207 + + F++ D DG + EE ++ V + LQ + Sbjct: 1 MAEALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLI 41 Score = 28.9 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 24/63 (38%), Gaps = 8/63 (12%) Query: 47 IEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEE 106 ++ LY+L DG + KEE + F D++ D +G + EE Sbjct: 77 LKILYKLMDADG-----DGKLTKEE--VTTFFKKFGYEKVVDQIMKA-DANGDGYITLEE 128 Query: 107 FAR 109 F Sbjct: 129 FLA 131 >5E37-A nrPDB Length = 356 Score = 62.4 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 66/171 (38%), Gaps = 20/171 (11%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQ----------LALFKTNKKESLFADRVFD 92 S +++E L FK V +G I++EE + + + + +R + Sbjct: 24 SKAKMEELERRFKMAD--VDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCME 81 Query: 93 LFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATL 152 +D +G++ FEEF + + + +F+ D G I E+ ++ + Sbjct: 82 QYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASL- 140 Query: 153 AESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 +E ++D + D G+I+ E+ + LK+MT Sbjct: 141 ------GNPVSLEKLVDLM-QMYDKDDSGQIEFPEFLLMFRNSLLDLKDMT 184 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 37/161 (22%), Positives = 62/161 (38%), Gaps = 12/161 (7%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADR--VFDLFDTKHNG 100 E+E E + V DG+I+ EEF+ ++ E A+ F D NG Sbjct: 72 PEDELERCMEQYD-----VNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNG 126 Query: 101 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV-ATLAESGMNL 159 +G E ++ + + +K+ Q+YD G IE E M + L M Sbjct: 127 TIGATELSKLFASLGNPVSL-EKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTT 185 Query: 160 KDTVIEDIIDKTFEEAD-TKHDGKI--DKEEWRSLVLRHPS 197 T+ E + D + D + +EE +L+ +P Sbjct: 186 YMTLDEAGAGSSGSLVDAVEGDMTLIFSEEELDALISANPD 226 Score = 28.1 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 28/58 (48%) Query: 140 ERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPS 197 + V+ + A E M+ + +++ F+ AD +G ID+EE R+L+ S Sbjct: 3 SARSVRVVPRAATFEGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMES 60 >5MWC-D nrPDB Length = 311 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 8/83 (9%) Query: 110 ALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID 169 + P ++++ F+ +D GFI+R+E ++ +G L D D Sbjct: 139 MANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIR----LTGEQLTDEDP----D 190 Query: 170 KTFEEADTKHDGKIDKEEWRSLV 192 + F ++DT +G+ID +E+ +V Sbjct: 191 EIFGDSDTDKNGRIDFDEFLKMV 213 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 39/136 (28%), Gaps = 19/136 (13%) Query: 26 QSGGLGDPELLARDTVFSVS------EIEALYELFKKISSAVIDDGLINKEEFQLALFKT 79 ++ D L + ++ E + F + + +L Sbjct: 98 RTVQFEDGASLTVNYRYTYEGSHIKGEAQVKGTGFPADGPVMAN-----------SLTAM 146 Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 E ++ F FD +G + EEF + D+ F D + G I Sbjct: 147 VPSEEELSE-CFRTFDKDGDGFIDREEF-GGIIRLTGEQLTDEDPDEIFGDSDTDKNGRI 204 Query: 140 ERQEVKQMVVATLAES 155 + E +MV Sbjct: 205 DFDEFLKMVENVQLSM 220 >2K2I-A nrPDB Length = 79 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 43/83 (51%), Gaps = 8/83 (9%) Query: 112 SVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKT 171 + ++I +F+L+D + G I + +K++ E G NL D ++++ID Sbjct: 1 TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAK----ELGENLTDEELQEMID-- 54 Query: 172 FEEADTKHDGKIDKEEWRSLVLR 194 EAD DG++ ++E+ ++ + Sbjct: 55 --EADRDGDGEVSEQEFLRIMKK 75 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 F LFD G + F+ + ++ D+++ D G + QE +++ Sbjct: 17 FKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMK 74 Score = 27.7 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 27/73 (36%), Gaps = 4/73 (5%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 + EI ++LF + I + + +L N + + + + D +G + Sbjct: 9 TKEEILKAFKLFDDDETGKISFKNLKRVAKEL---GENLTDEELQEMIDEA-DRDGDGEV 64 Query: 103 GFEEFARALSVFH 115 +EF R + Sbjct: 65 SEQEFLRIMKKTS 77 >2B1U-A nrPDB Length = 71 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 34/74 (45%), Gaps = 8/74 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + + +F+ +D G I E+++ + L + ++ +D EAD DG Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAG--------LGQPLPQEELDAMIREADVDQDG 57 Query: 182 KIDKEEWRSLVLRH 195 +++ EE+ ++ + Sbjct: 58 RVNYEEFARMLAQE 71 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKT-NKKESLFADRVFDLFDTKHNGILG 103 +++ + F + DG I +E + A+ D + D +G + Sbjct: 6 EDLQVAFRAFDQDG-----DGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVN 60 Query: 104 FEEFARALS 112 +EEFAR L+ Sbjct: 61 YEEFARMLA 69 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 27/61 (44%), Gaps = 7/61 (11%) Query: 91 FDLFDTKHNGILGFEEFARALSVF---HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 F FD +G + +E RA++ P +D I + D+ Q G + +E +M Sbjct: 12 FRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREA----DVDQDGRVNYEEFARM 67 Query: 148 V 148 + Sbjct: 68 L 68 >1JFJ-A nrPDB Length = 134 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 17/144 (11%) Query: 53 LFKKISSAVIDDGLINKEEFQLALFKTNK-KESLFADRVFDLFDTKHNGILGFEEFARAL 111 LFK+I V DG ++ EE + + K K +F D NG + EFA+ Sbjct: 5 LFKEID--VNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 112 SVFHPNAPIDDK--IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID 169 DDK + ++L D+ G + ++E V + + G+ + + Sbjct: 63 GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEE----VTSFFKKHGI--------EKVA 110 Query: 170 KTFEEADTKHDGKIDKEEWRSLVL 193 + +AD DG I EE+ L Sbjct: 111 EQVMKADANGDGYITLEEFLEFSL 134 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 6/110 (5%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 A+ +F D +G + +EE +S + + F+ D G I++ E Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN-EQLLQLIFKSIDADGNGEIDQNEFA 59 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 + + G +L D I + ++ D DGK+ KEE S +H Sbjct: 60 KFYGSI---QGQDLSDDKIGLKV--LYKLMDVDGDGKLTKEEVTSFFKKH 104 Score = 32.3 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 20/41 (48%) Query: 167 IIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYL 207 + + F+E D DG + EE ++ V + ++ LQ + Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLI 41 >3E3R-A nrPDB Length = 204 Score = 60.1 bits (144), Expect = 7e-10, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 66/167 (39%), Gaps = 15/167 (8%) Query: 47 IEALYELFKKISSAVIDDGLINKEEF--QLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 I+ L F+++ ++ +EF LA ++ A+ V +D +G L Sbjct: 36 IQGLARFFRQLDRDGSRS--LDADEFRQGLAKLGLVLDQAE-AEGVCRKWDRNGSGTLDL 92 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 EEF RAL A + I +F D G + +++ + + A + + Sbjct: 93 EEFLRALRPPMSQA-REAVIAAAFAKLDRSGDGVVTVDDLRGVY-SGRAHPKVRSGEWTE 150 Query: 165 EDIIDKTFEEAD-TKHDGKIDKEEWRS-------LVLRHPSLLKNMT 203 ++++ + + D ++ DG++ E++ + + MT Sbjct: 151 DEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMT 197 >2LV7-A nrPDB Length = 100 Score = 60.1 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 8/68 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++I +F+++D GFI +QE+ + + E ++ + D DG Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPN--------EVELEVIIQRLDMDGDG 87 Query: 182 KIDKEEWR 189 ++D EE+ Sbjct: 88 QVDFEEFV 95 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 28 GGLGDPELLARDTVFSV-----SEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTN 80 G P LL+ + EI +++F + +G I+K+E A+ Sbjct: 14 GIYTVPNLLSEQRPVDIPEDELEEIREAFKVFDRDG-----NGFISKQELGTAMRSLGYM 68 Query: 81 KKESLFADRVFDLFDTKHNGILGFEEFARAL 111 E + + D +G + FEEF L Sbjct: 69 PNEVEL-EVIIQRLDMDGDGQVDFEEFVTLL 98 Score = 35.0 bits (79), Expect = 0.025, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 F +FD NG + +E A+ P + ++ Q D+ G ++ +E ++ Sbjct: 42 FKVFDRDGNGFISKQELGTAM-RSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFVTLL 98 >4N5X-A nrPDB Length = 199 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 59/149 (39%), Gaps = 18/149 (12%) Query: 48 EALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF 107 E L++ + V+D G + + L + +++ +++F D +G L FEEF Sbjct: 25 ETLFQALDRNGDGVVDIGELQEGLRNLGI--PLGQDAE--EKIFTTGDVNKDGKLDFEEF 80 Query: 108 ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 + L + K+ +F+ D G IE E+ Q + L T+ E Sbjct: 81 MKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSL--------QTLGLTISEQQ 126 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + + D +D EWR L +P Sbjct: 127 AELILQSIDVDGTMTVDWNEWRDYFLFNP 155 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 11/79 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 FQ D G ++ E+++ + NL + +D +K F D DGK+D EE Sbjct: 28 FQALDRNGDGVVDIGELQEGLR--------NLGIPLGQDAEEKIFTTGDVNKDGKLDFEE 79 Query: 188 WRSLVLRHPSLLKNMTLQY 206 + + H K M L + Sbjct: 80 FMKYLKDHE---KKMKLAF 95 >4ZCV-A nrPDB Length = 165 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 59/149 (39%), Gaps = 18/149 (12%) Query: 48 EALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF 107 E L++ + V+D G + + L + +++ +++F D +G L FEEF Sbjct: 16 ETLFQALDRNGDGVVDIGELQEGLRNLGI--PLGQDAE--EKIFTTGDVNKDGKLDFEEF 71 Query: 108 ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 + L + K+ +F+ D G IE E+ Q + L T+ E Sbjct: 72 MKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSL--------QTLGLTISEQQ 117 Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + + D +D EWR L +P Sbjct: 118 AELILQSIDVDGTMTVDWNEWRDYFLFNP 146 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 11/79 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 FQ D G ++ E+++ + NL + +D +K F D DGK+D EE Sbjct: 19 FQALDRNGDGVVDIGELQEGLR--------NLGIPLGQDAEEKIFTTGDVNKDGKLDFEE 70 Query: 188 WRSLVLRHPSLLKNMTLQY 206 + + H K M L + Sbjct: 71 FMKYLKDHE---KKMKLAF 86 >4WPX-A nrPDB Length = 177 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 71/167 (42%), Gaps = 28/167 (16%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQL---ALFKTNKKESLFADRVFDLFDTKHNG 100 + I +ELF DGL++ EEF+ AL K+ + D + N Sbjct: 25 KTRISEAFELFDS-----NKDGLLSYEEFRFVLRALGFDLPKQQTY-DMLVRHGQRPANW 78 Query: 101 ILG------FEEF----ARALS-VFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + +F A+AL+ D++ +F+L+D+ +G I +++++ Sbjct: 79 PHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQ 138 Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 G N+ D I+ +I++ D+ G +D++E+ L++ Sbjct: 139 QV----GNNIPDADIQAMIEEF----DSNGKGGVDEDEFLRLMMSKK 177 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF-QLALFKTNKKESLFADRVFDLFDTKHNGI 101 E+ + LF G+I +++ ++ N + + FD+ G Sbjct: 109 PRDELRRAFRLFDVDGK-----GMITEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGG 163 Query: 102 LGFEEFARAL 111 + +EF R + Sbjct: 164 VDEDEFLRLM 173 Score = 29.6 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 18/45 (40%) Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 +Q+ N + I + FE D+ DG + EE+R Sbjct: 5 RQIQYTIPPREDYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFR 49 >5COC-A nrPDB Length = 130 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 30/75 (40%), Gaps = 8/75 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 62 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 115 Query: 102 LGFEEFARALSVFHP 116 + F EF ++ Sbjct: 116 IDFPEFLTMMARKMK 130 Score = 56.6 bits (135), Expect = 9e-09, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 115 Query: 183 IDKEEWRSLVLRH 195 ID E+ +++ R Sbjct: 116 IDFPEFLTMMARK 128 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 34/109 (31%), Gaps = 2/109 (1%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 E + K + + L + A + + F + F LFD +G + Sbjct: 24 EEQRNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEECIAEFKEA-FSLFDKDGDGTITT 82 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 +E + P + ++ D G I+ E M+ + Sbjct: 83 KELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK 130 >5H7D-E nrPDB Length = 120 Score = 57.8 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNG 107 Query: 182 KIDKEEWRSLVLR 194 ID E+ +++ R Sbjct: 108 TIDFPEFLTMMAR 120 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 28/72 (38%), Gaps = 8/72 (11%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 + + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 55 IQAFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 108 Query: 102 LGFEEFARALSV 113 + F EF ++ Sbjct: 109 IDFPEFLTMMAR 120 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 21/58 (36%), Gaps = 1/58 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 F LFD +G + +E + P + ++ D G I+ E M+ Sbjct: 62 FSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 >2Q4U-A nrPDB Length = 272 Score = 56.6 bits (135), Expect = 8e-09, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 67/170 (39%), Gaps = 18/170 (10%) Query: 47 IEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRV-------FDLFDTKHN 99 +++ F + I+ ++ + F+ L K K+ + +RV +D + Sbjct: 13 FLQIWQHFDADDNGYIEGKELD-DFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFD 71 Query: 100 GILGFEEFARA--------LSVFHPNAPIDDKIHFS--FQLYDLKQQGFIERQEVKQMVV 149 G L EE A L +F AP+D+ + F ++ YD G+I E+K + Sbjct: 72 GRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLK 131 Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLL 199 + + +++ D + D DG++D + ++ + L Sbjct: 132 DLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFL 181 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 49/157 (31%), Gaps = 15/157 (9%) Query: 46 EIEALYELFKKISSAVID----DGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 E ++ + SS I + Q K + D + +FD +G Sbjct: 105 EFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGR 164 Query: 102 LGFEEFARALSVF-----------HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 L + AR L++ F YD+ + G +E EV V Sbjct: 165 LDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKD 224 Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 + ++ ++ + D DGKI K E Sbjct: 225 MMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSE 261 >3J04-B nrPDB Length = 143 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 56/154 (36%), Gaps = 17/154 (11%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHN 99 F S+I+ E F I DG I+KE+ LA N + + + Sbjct: 1 FDQSQIQEFKEAFNMIDQN--RDGFIDKEDLHDMLASMGKNPTDEYLEGMMSEA-----P 53 Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 G + F F +D I +F +D + GFI +++++ Sbjct: 54 GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTM-------- 105 Query: 160 KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 D ++ +D+ + EA G + E+ ++ Sbjct: 106 GDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILK 139 >3AAJ-A nrPDB Length = 167 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 63/169 (37%), Gaps = 34/169 (20%) Query: 50 LYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLF----ADRVFDLFDTKHNGILGFE 105 L+ +F+++ G+I+ E Q AL N + F + +FD ++ + F Sbjct: 6 LWNVFQRVDKD--RSGVISDTELQQALS--NGTWTPFNPVTVRSIISMFDRENKAGVNFS 61 Query: 106 EFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIE 165 EF + F+ YD G I++ E+KQ A SG L D Sbjct: 62 EFTGVWKYITDWQNV-------FRTYDRDNSGMIDKNELKQ------ALSGYRLSD---- 104 Query: 166 DIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTF 214 D + D + G+I +++ + LQ L DI + Sbjct: 105 QFHDILIRKFDRQGRGQIAFDDFIQGC---------IVLQRLTDIFRRY 144 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 45/108 (41%), Gaps = 12/108 (11%) Query: 47 IEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEE 106 I +F+ + G+I+K E + AL + F D + FD + G + F++ Sbjct: 70 ITDWQNVFRTYDRD--NSGMIDKNELKQALSG-YRLSDQFHDILIRKFDRQGRGQIAFDD 126 Query: 107 FARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI--ERQEVKQMVVATL 152 F + V ++ F+ YD Q G+I ++ MV + + Sbjct: 127 FIQGCIVL-------QRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 167 >2BL0-B nrPDB Length = 145 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 62/157 (39%), Gaps = 30/157 (19%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNG 100 S +I+ +++F K +DG ++ EE AL N + G Sbjct: 3 SADQIQECFQIFDKD-----NDGKVSIEELGSALRSLGKNPTNAELNTI---------KG 48 Query: 101 ILGFEEF----ARALSVFHPNAPIDD--KIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 L +EF + + P + ++ +F+ D + G I+ E++Q++ Sbjct: 49 QLNAKEFDLATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLL------ 102 Query: 155 SGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 +NL D + +++ +E DG I+ E + + Sbjct: 103 --LNLGDALTSSEVEELMKEVSVSGDGAINYESFVDM 137 Score = 27.3 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 26/71 (36%), Gaps = 5/71 (7%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNG 100 + + + + F+ + +G I + E + L S + + ++ +G Sbjct: 71 PTEQSKEMLDAFRALDK--EGNGTIQEAELRQLLLNLGDALTSSEVEELMKEV-SVSGDG 127 Query: 101 ILGFEEFARAL 111 + +E F L Sbjct: 128 AINYESFVDML 138 >2RO8-A nrPDB Length = 79 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T +SE + + LF K DG I +E + N E+ D + ++ D Sbjct: 5 TDEQISEFKEAFSLFDKDG-----DGCITTKELGTVMRSLGQNPTEAELQDMINEV-DAD 58 Query: 98 HNGILGFEEFARALSVFHPNA 118 NG + F EF ++ + Sbjct: 59 GNGTIDFPEFLNLMARKMKDT 79 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 62 Query: 183 IDKEEWRSLVLRH 195 ID E+ +L+ R Sbjct: 63 IDFPEFLNLMARK 75 Score = 33.5 bits (75), Expect = 0.071, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 22/63 (34%), Gaps = 1/63 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F LFD +G + +E + P + ++ D G I+ E ++ Sbjct: 16 FSLFDKDGDGCITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMAR 74 Query: 151 TLA 153 + Sbjct: 75 KMK 77 >1JC2-A nrPDB Length = 76 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 42/77 (54%), Gaps = 8/77 (10%) Query: 116 PNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA 175 ++++ F+++D GFI+ +E+ +++ A + VIE+ I+ +++ Sbjct: 4 AKGKSEEELANCFRIFDKNADGFIDIEELGEILRA--------TGEHVIEEDIEDLMKDS 55 Query: 176 DTKHDGKIDKEEWRSLV 192 D +DG+ID +E+ ++ Sbjct: 56 DKNNDGRIDFDEFLKMM 72 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNG 100 S E+ + +F K DG I+ EE L + E D + D D ++G Sbjct: 8 SEEELANCFRIFDK-----NADGFIDIEELGEILRATGEHVIEEDIEDLMKDS-DKNNDG 61 Query: 101 ILGFEEFARAL 111 + F+EF + + Sbjct: 62 RIDFDEFLKMM 72 >2I08-A nrPDB Length = 78 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F LYD G I +E+ ++ + G+N + ++D+I+ E D +G Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSL----GLNPTEAELQDMIN----EVDADGNGT 62 Query: 183 IDKEEWRSLVLR 194 ID E+ +++ R Sbjct: 63 IDFPEFLTMMAR 74 Score = 53.5 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 31/79 (39%), Gaps = 8/79 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + L+ K DG I +E + N E+ D + ++ D Sbjct: 5 TEEQIAEFKEAFSLYDKDG-----DGTITTKELGTVMRSLGLNPTEAELQDMINEV-DAD 58 Query: 98 HNGILGFEEFARALSVFHP 116 NG + F EF ++ Sbjct: 59 GNGTIDFPEFLTMMARIMK 77 Score = 34.6 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 23/63 (36%), Gaps = 1/63 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F L+D +G + +E + N P + ++ D G I+ E M+ Sbjct: 16 FSLYDKDGDGTITTKELGTVMRSLGLN-PTEAELQDMINEVDADGNGTIDFPEFLTMMAR 74 Query: 151 TLA 153 + Sbjct: 75 IMK 77 >2K7C-A nrPDB Length = 72 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 7/72 (9%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 ++ +F+ +D G I E+++ A G + IE+ + D DG+ Sbjct: 8 ELRDAFREFDTNGDGEISTSELRE---AMRKLLGHQVGHRDIEE----IIRDVDLNGDGR 60 Query: 183 IDKEEWRSLVLR 194 +D EE+ ++ R Sbjct: 61 VDFEEFVRMMSR 72 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 7/72 (9%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFAD--RVFDLFDTKHNGI 101 V E+ + F DG I+ E + A+ K + D + D +G Sbjct: 6 VKELRDAFREFDTNG-----DGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGR 60 Query: 102 LGFEEFARALSV 113 + FEEF R +S Sbjct: 61 VDFEEFVRMMSR 72 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 23/58 (39%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 F FDT +G + E A+ + I + DL G ++ +E +M+ Sbjct: 13 FREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMM 70 >2AMI-A nrPDB Length = 96 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +I +F L+D G I+ +E+K + A L ++ I K E D G Sbjct: 30 QEIREAFDLFDTDGSGTIDAKELKVAMRA--------LGFEPKKEEIKKMISEIDKDGSG 81 Query: 182 KIDKEEWRSLV 192 ID EE+ +++ Sbjct: 82 TIDFEEFLTMM 92 Score = 50.1 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 32/78 (41%), Gaps = 8/78 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T EI ++LF S G I+ +E ++A+ K+ + ++ D Sbjct: 25 TEEQKQEIREAFDLFDTDGS-----GTIDAKELKVAMRALGFEPKKEEIKKMISEI-DKD 78 Query: 98 HNGILGFEEFARALSVFH 115 +G + FEEF ++ Sbjct: 79 GSGTIDFEEFLTMMTAKM 96 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 1/62 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FDLFDT +G + +E A+ P ++I D G I+ +E M+ A Sbjct: 36 FDLFDTDGSGTIDAKELKVAMRAL-GFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTA 94 Query: 151 TL 152 + Sbjct: 95 KM 96 >4Q57-A nrPDB Length = 65 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E + + LF K DG I +E + N E+ D + ++ D NG Sbjct: 1 IAEFKEAFSLFDKDG-----DGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGT 54 Query: 102 LGFEEFARALS 112 + F EF ++ Sbjct: 55 IDFPEFLTMMA 65 Score = 53.1 bits (126), Expect = 9e-08, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 8/70 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I +E+ ++ + G N + ++D+I+ E D +G Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAELQDMIN----EVDADGNGT 54 Query: 183 IDKEEWRSLV 192 ID E+ +++ Sbjct: 55 IDFPEFLTMM 64 Score = 36.2 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 21/58 (36%), Gaps = 1/58 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 F LFD +G + +E + P + ++ D G I+ E M+ Sbjct: 8 FSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 64 >1OQP-A nrPDB Length = 77 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 41/80 (51%), Gaps = 8/80 (10%) Query: 115 HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEE 174 ++I +F+L+D G I ++++++ E G NL + ++++I E Sbjct: 2 SGERDSREEILKAFRLFDDDNSGTITIKDLRRVAK----ELGENLTEEELQEMI----AE 53 Query: 175 ADTKHDGKIDKEEWRSLVLR 194 AD D +ID++E+ ++ + Sbjct: 54 ADRNDDNEIDEDEFIRIMKK 73 Score = 27.7 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 24/59 (40%), Gaps = 1/59 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 F LFD ++G + ++ R ++ ++++ D I+ E +++ Sbjct: 15 FRLFDDDNSGTITIKD-LRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMK 72 >2K2A-A nrPDB Length = 70 Score = 53.1 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 36/73 (49%), Gaps = 8/73 (10%) Query: 120 IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 + ++ +F+LYD + G+I +++++ L +T+ + +D +E D Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILA--------ELDETLSSEDLDAMIDEIDADG 52 Query: 180 DGKIDKEEWRSLV 192 G +D EE+ ++ Sbjct: 53 SGTVDFEEFMGVM 65 Score = 34.6 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 27/69 (39%), Gaps = 4/69 (5%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILG 103 E+ + L+ K + I ++ + +L S D + D D +G + Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAEL----DETLSSEDLDAMIDEIDADGSGTVD 57 Query: 104 FEEFARALS 112 FEEF ++ Sbjct: 58 FEEFMGVMT 66 >1OZS-A nrPDB Length = 73 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 41/77 (53%), Gaps = 8/77 (10%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 ++++ F+++D G+I+ +E+K M+ A +T+ ED I++ ++ D Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA--------TGETITEDDIEELMKDGD 53 Query: 177 TKHDGKIDKEEWRSLVL 193 +DG+ID +E+ + Sbjct: 54 KNNDGRIDYDEFLEFMK 70 Score = 35.8 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 23/72 (31%), Gaps = 1/72 (1%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 K +F +FD +G + EE L +D I + D G I Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA-TGETITEDDIEELMKDGDKNNDGRI 60 Query: 140 ERQEVKQMVVAT 151 + E + + Sbjct: 61 DYDEFLEFMKGV 72 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 32/71 (45%), Gaps = 6/71 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL-FADRVFDLFDTKHNGI 101 S E+ L+ +F K DG I+ EE ++ L T + + + + D ++G Sbjct: 5 SEEELSDLFRMFDK-----NADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGR 59 Query: 102 LGFEEFARALS 112 + ++EF + Sbjct: 60 IDYDEFLEFMK 70 >2M97-A nrPDB Length = 69 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 40/73 (54%), Gaps = 8/73 (10%) Query: 120 IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 ++++ F+++D GFI+R+E ++ + + ++ +D+ F ++DT Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRL--------TGEQLTDEDVDEIFGDSDTDK 52 Query: 180 DGKIDKEEWRSLV 192 +G+ID +E+ ++ Sbjct: 53 NGRIDFDEFLKMM 65 Score = 36.2 bits (82), Expect = 0.011, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFADRVFDLFDTKHNGI 101 S E+ + +F K +G I++EEF + + D +F DT NG Sbjct: 1 SEEELSECFRIFDKDG-----NGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGR 55 Query: 102 LGFEEFARAL 111 + F+EF + + Sbjct: 56 IDFDEFLKMM 65 >1C7W-A nrPDB Length = 81 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 40/84 (47%), Gaps = 7/84 (8%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 +++I +F+++D G I+ E K ++ ++ + + +++ +EAD Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKV-------GEEPLTDAEVEEAMKEAD 55 Query: 177 TKHDGKIDKEEWRSLVLRHPSLLK 200 +G ID E+ L+ + + LK Sbjct: 56 EDGNGVIDIPEFMDLIKKSKNALK 79 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 28/70 (40%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 + + R F +FD +G++ F+EF + D ++ + + D G I Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVI 62 Query: 140 ERQEVKQMVV 149 + E ++ Sbjct: 63 DIPEFMDLIK 72 Score = 33.5 bits (75), Expect = 0.072, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 7/72 (9%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKE--SLFADRVFDLFDTKHNG 100 EI +++F DG+I+ +EF+ + K ++ + D NG Sbjct: 6 DEEEILRAFKVFDANG-----DGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNG 60 Query: 101 ILGFEEFARALS 112 ++ EF + Sbjct: 61 VIDIPEFMDLIK 72 >5OTJ-D nrPDB Length = 110 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ +D G I E+ + + D + + E DT DG ID E Sbjct: 9 FKRFDTNGDGKISLSELTDALRTLG---------STSADEVQRMMAEIDTDGDGFIDFNE 59 Query: 188 WRSLVLRHPSLLKNMTLQYLKDITT 212 + S +P L+K++ + ++ + Sbjct: 60 FISFCNANPGLMKDVAKVFKGELNS 84 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 24/64 (37%), Gaps = 2/64 (3%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 +R+F FDT +G + E AL + D++ D GFI+ E Sbjct: 5 MERIFKRFDTNGDGKISLSELTDAL--RTLGSTSADEVQRMMAEIDTDGDGFIDFNEFIS 62 Query: 147 MVVA 150 A Sbjct: 63 FCNA 66 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 25/65 (38%), Gaps = 5/65 (7%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 ++E +++ F DG I+ E AL + R+ DT +G + F Sbjct: 3 DDMERIFKRFDTNG-----DGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDF 57 Query: 105 EEFAR 109 EF Sbjct: 58 NEFIS 62 Score = 28.9 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 166 DIIDKTFEEADTKHDGKIDKEEWRSLVL 193 D +++ F+ DT DGKI E + Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALR 30 >6IIE-A nrPDB Length = 93 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Query: 115 HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD-TVIEDIIDKTFE 173 +DK+ F+F+LYD + G ++ EV ++++ + + D + + I+ + + Sbjct: 2 MEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 174 EADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 E D G + + EW LL + L+ Sbjct: 62 EIDYDGSGSVSQAEWVRAGATTVPLLVLLGLE 93 >1SR6-C nrPDB Length = 156 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 66/162 (40%), Gaps = 17/162 (10%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNG 100 S EI+ L ++F+ DG ++ F+L + + VF + T G Sbjct: 2 KLSQDEIDDLKDVFELFDFWDGRDGAVDA--FKLGDVCRCLGINPRNEDVFAVGGTHKMG 59 Query: 101 --ILGFEEFARALSVFHP--NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESG 156 L FEEF A D +F+ +D + QGFI E++ ++ A Sbjct: 60 EKSLPFEEFLPAYEGLMDCEQGTFAD-YMEAFKTFDREGQGFISGAELRHVLTA------ 112 Query: 157 MNLKDTVIEDIIDKTFEEADTKHD--GKIDKEEWRSLVLRHP 196 L + + ++ +D+ + D + D G + E++ V+ P Sbjct: 113 --LGERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAGP 152 >5JOJ-A nrPDB Length = 97 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 ++ +F D G+I E+ + A L + +I + D DG+ Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLP----LPGYRVREITENLMATGDLDQDGR 68 Query: 183 IDKEEWRS 190 I +E+ Sbjct: 69 ISFDEFIK 76 Score = 31.6 bits (70), Expect = 0.27, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 22/61 (36%), Gaps = 3/61 (4%) Query: 91 FDLFDTKHNGILGFEEF---ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 F DT NG + F E +A + P + + DL Q G I E ++ Sbjct: 18 FAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKI 77 Query: 148 V 148 Sbjct: 78 F 78 Score = 31.2 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 12/85 (14%), Positives = 26/85 (30%), Gaps = 9/85 (10%) Query: 28 GGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFA 87 G + D E++ E+ + + I +N L + Sbjct: 4 GSVSDEEMM---------ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREIT 54 Query: 88 DRVFDLFDTKHNGILGFEEFARALS 112 + + D +G + F+EF + Sbjct: 55 ENLMATGDLDQDGRISFDEFIKIFH 79 >5ZGM-A nrPDB Length = 110 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 9/109 (8%) Query: 87 ADRVFDLFDTKHN-GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 AD + + G ++ F + + + + ++ F++ D Q GFIE +E+K Sbjct: 9 ADDINKAVSAFKDPGTFDYKRFFQLVGL---KGKSEAQVKEVFEILDKDQSGFIEEEELK 65 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ + G +L DT + + D+ HDGKI +E+ +V + Sbjct: 66 SVLKG-FSAHGRDLSDTETKAL----LAAGDSDHDGKIGADEFAKMVAQ 109 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 31/92 (33%), Gaps = 3/92 (3%) Query: 59 SAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 SA D G + + F L K VF++ D +G + EE L F + Sbjct: 17 SAFKDPGTFDYKRF-FQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHG 75 Query: 119 P--IDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 D + D G I E +MV Sbjct: 76 RDLSDTETKALLAAGDSDHDGKIGADEFAKMV 107 >5JOL-A nrPDB Length = 82 Score = 50.4 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 ++ +F D G+I E+ + A L + +I + D DG+ Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLP----LPGYRVREITENLMATGDLDQDGR 68 Query: 183 IDKEEWRS 190 I +E+ Sbjct: 69 ISFDEFIK 76 Score = 31.6 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 22/61 (36%), Gaps = 3/61 (4%) Query: 91 FDLFDTKHNGILGFEEF---ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 F DT NG + F E +A + P + + DL Q G I E ++ Sbjct: 18 FAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKI 77 Query: 148 V 148 Sbjct: 78 F 78 Score = 31.2 bits (69), Expect = 0.41, Method: Composition-based stats. Identities = 12/85 (14%), Positives = 26/85 (30%), Gaps = 9/85 (10%) Query: 28 GGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFA 87 G + D E++ E+ + + I +N L + Sbjct: 4 GSVSDEEMM---------ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREIT 54 Query: 88 DRVFDLFDTKHNGILGFEEFARALS 112 + + D +G + F+EF + Sbjct: 55 ENLMATGDLDQDGRISFDEFIKIFH 79 >2KSZ-A nrPDB Length = 76 Score = 50.4 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 125 HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKID 184 +F L+D G I +E+ ++ + N + ++D+I E D +G I+ Sbjct: 13 KEAFGLFDKDGDGCITVEELATVIRSL----DQNPTEEELQDMI----SEVDADGNGTIE 64 Query: 185 KEEWRSLVLRH 195 +E+ SL+ + Sbjct: 65 FDEFLSLMAKK 75 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 28/71 (39%), Gaps = 8/71 (11%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGILG 103 + + + LF K DG I EE + N E D + ++ D NG + Sbjct: 11 DFKEAFGLFDKDG-----DGCITVEELATVIRSLDQNPTEEELQDMISEV-DADGNGTIE 64 Query: 104 FEEFARALSVF 114 F+EF ++ Sbjct: 65 FDEFLSLMAKK 75 Score = 36.2 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 F LFD +G + EE + P ++++ D G IE E ++ Sbjct: 16 FGLFDKDGDGCITVEE-LATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 >2G9B-A nrPDB Length = 263 Score = 50.1 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 55/151 (36%), Gaps = 37/151 (24%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL---------FADRVFDLFD 95 E + + G I EE + L +K + + D + LFD Sbjct: 103 EEFMKTWRKYDTD-----HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 157 Query: 96 TKHNGILGFEEFARALSV-------FHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 + ++G L E AR L V F + + +F+LYD G+I+ E+ Sbjct: 158 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL---- 213 Query: 149 VATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 D +++D+ +K +E D + Sbjct: 214 ------------DALLKDLCEKNKQELDINN 232 Score = 50.1 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 39/82 (47%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++ +++ YD GFIE +E+K + L ++ + DT + + D + D+ +DG Sbjct: 103 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 162 Query: 182 KIDKEEWRSLVLRHPSLLKNMT 203 K++ E L+ + L Sbjct: 163 KLELTEMARLLPVQENFLLKFQ 184 Score = 43.5 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 7/103 (6%) Query: 92 DLFDTKHNGILGFEE---FARALSVFHPNAPIDDKIHFS----FQLYDLKQQGFIERQEV 144 +DT H+G + EE F + L D K+ +L+D G +E E+ Sbjct: 110 RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 169 Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 +++ + +K FE D +G ID+ E Sbjct: 170 ARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 212 >2LVK-A nrPDB Length = 77 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 9/73 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ +D G I E+ + + D + + E DT DG ID E Sbjct: 8 FKRFDTNGDGKISLSELTDALRTLG---------STSADEVQRMMAEIDTDGDGFIDFNE 58 Query: 188 WRSLVLRHPSLLK 200 + S +P L+K Sbjct: 59 FISFCNANPGLMK 71 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 +R+F FDT +G + E AL + D++ D GFI+ E Sbjct: 4 MERIFKRFDTNGDGKISLSELTDAL--RTLGSTSADEVQRMMAEIDTDGDGFIDFNE 58 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 25/65 (38%), Gaps = 5/65 (7%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 ++E +++ F DG I+ E AL + R+ DT +G + F Sbjct: 2 DDMERIFKRFDTNG-----DGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDF 56 Query: 105 EEFAR 109 EF Sbjct: 57 NEFIS 61 Score = 27.7 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 166 DIIDKTFEEADTKHDGKIDKEEWRSLVL 193 D +++ F+ DT DGKI E + Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALR 29 >1Y1X-A nrPDB Length = 191 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 24/150 (16%), Positives = 48/150 (32%), Gaps = 19/150 (12%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 E+ + S I +N + + +D H+G + Sbjct: 25 DNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHM----YDKNHSGEI 80 Query: 103 GFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDT 162 F+EF L F + + F+ D G ++ E V A L SG + + Sbjct: 81 TFDEFKD-LHHFILS------MREGFRKRDSSGDGRLDSNE----VRAALLSSGYQVSEQ 129 Query: 163 VIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + + + D + G + +++ L Sbjct: 130 TFQAL----MRKFDRQRRGSLGFDDYVELS 155 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 48/137 (35%), Gaps = 21/137 (15%) Query: 74 LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALS---VFHPNAPIDDKIHFSFQL 130 A + ++ F DT +G + E ALS V A + +H + Sbjct: 16 YAPSARHMNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLH----M 71 Query: 131 YDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRS 190 YD G I E K + L+ + F + D+ DG++D E R+ Sbjct: 72 YDKNHSGEITFDEFKDLHHFILSMR--------------EGFRKRDSSGDGRLDSNEVRA 117 Query: 191 LVLRHPSLLKNMTLQYL 207 +L + T Q L Sbjct: 118 ALLSSGYQVSEQTFQAL 134 >5PAL-A nrPDB Length = 109 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 9/109 (8%) Query: 87 ADRVFDLFDTKHN-GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 AD + + G ++ F + + D ++ F++ D Q GFIE +E+K Sbjct: 8 ADDINKAISAFKDPGTFDYKRFFHLVGL---KGKTDAQVKEVFEILDKDQSGFIEEEELK 64 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ + G +L DT + + D+ HDGKI +E+ +V + Sbjct: 65 GVLKG-FSAHGRDLNDTETKAL----LAAGDSDHDGKIGADEFAKMVAQ 108 Score = 35.0 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 31/92 (33%), Gaps = 3/92 (3%) Query: 59 SAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 SA D G + + F L K VF++ D +G + EE L F + Sbjct: 16 SAFKDPGTFDYKRF-FHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHG 74 Query: 119 P--IDDKIHFSFQLYDLKQQGFIERQEVKQMV 148 D + D G I E +MV Sbjct: 75 RDLNDTETKALLAAGDSDHDGKIGADEFAKMV 106 >1YX7-A nrPDB Length = 83 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 + ++ +F+ D G++ E++ +V A L +++ K + AD Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAY--KALSKDKVKEASAKLIKMADKN 61 Query: 179 HDGKIDKEEWRSL 191 DGKI KEE+ + Sbjct: 62 SDGKISKEEFLNA 74 Score = 33.1 bits (74), Expect = 0.089, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 20/64 (31%), Gaps = 5/64 (7%) Query: 88 DRVFDLFDTKHNGIL---GFEEFARALSVF--HPNAPIDDKIHFSFQLYDLKQQGFIERQ 142 + F D +G + + F L + + + ++ D G I ++ Sbjct: 10 EAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKISKE 69 Query: 143 EVKQ 146 E Sbjct: 70 EFLN 73 Score = 28.1 bits (61), Expect = 2.9, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 9/69 (13%) Query: 49 ALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRV-------FDLFDTKHNGI 101 L FKK+ + DG + E Q + + ++L D+V + D +G Sbjct: 8 ELEAAFKKLDANG--DGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 102 LGFEEFARA 110 + EEF A Sbjct: 66 ISKEEFLNA 74 >1ZMZ-A nrPDB Length = 98 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 34/74 (45%), Gaps = 8/74 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +I +F L+D G I+ +E+K + A L ++ I K E D + G Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRA--------LGFEPKKEEIKKMISEIDKEGTG 82 Query: 182 KIDKEEWRSLVLRH 195 K++ ++ +++ + Sbjct: 83 KMNFGDFLTVMTQK 96 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 32/88 (36%), Gaps = 12/88 (13%) Query: 31 GDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFAD 88 PEL EI ++LF G I+ +E ++A+ K+ Sbjct: 21 PKPELTEEQ----KQEIREAFDLFDADG-----TGTIDVKELKVAMRALGFEPKKEEIKK 71 Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHP 116 + ++ D + G + F +F ++ Sbjct: 72 MISEI-DKEGTGKMNFGDFLTVMTQKMS 98 Score = 35.0 bits (79), Expect = 0.023, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 23/62 (37%), Gaps = 1/62 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FDLFD G + +E A+ P ++I D + G + + ++ Sbjct: 37 FDLFDADGTGTIDVKELKVAMRA-LGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQ 95 Query: 151 TL 152 + Sbjct: 96 KM 97 >2OPO-A nrPDB Length = 86 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 9/76 (11%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ +D G I E+ + + + D + + E DT DG I +E Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLGSVTP---------DEVRRMMAEIDTDGDGFISFDE 67 Query: 188 WRSLVLRHPSLLKNMT 203 + + L+K+++ Sbjct: 68 FTDFARANRGLVKDVS 83 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 23/63 (36%), Gaps = 2/63 (3%) Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 +R+F FDT +G + E AL P D++ D GFI E Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGSVTP--DEVRRMMAEIDTDGDGFISFDEFTDF 71 Query: 148 VVA 150 A Sbjct: 72 ARA 74 Score = 33.9 bits (76), Expect = 0.064, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Query: 37 ARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDT 96 A DT +++ E +++ F DG I+ E AL R+ DT Sbjct: 3 AEDTPQDIADRERIFKRFDTNG-----DGKISSSELGDALKTLGSVTPDEVRRMMAEIDT 57 Query: 97 KHNGILGFEEF 107 +G + F+EF Sbjct: 58 DGDGFISFDEF 68 Score = 30.8 bits (68), Expect = 0.49, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 161 DTVIEDIIDK--TFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFV 218 + +DI D+ F+ DT DGKI E + S+ + + + +I T F+ Sbjct: 4 EDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGDGFI 63 Query: 219 FHSQVED 225 + D Sbjct: 64 SFDEFTD 70 >2NCO-A nrPDB Length = 102 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ YD G ++ E+ ++ T AE GM+ ED + + ADT DG + EE Sbjct: 21 FKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-VKIWLQMADTNSDGSVSLEE 79 Query: 188 WRSLVLRH 195 + L+++ Sbjct: 80 YEDLIIKS 87 Score = 30.4 bits (67), Expect = 0.67, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 27/70 (38%), Gaps = 9/70 (12%) Query: 48 EALYELFKKISSAVIDDGLI------NKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 L++ + K S + D I E ++ F K++ ++ DT +G Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMA---DTNSDGS 74 Query: 102 LGFEEFARAL 111 + EE+ + Sbjct: 75 VSLEEYEDLI 84 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPN------APIDDKIHFSFQLYDLKQQGFIE 140 A R+F +D +G L +E A L + P + + Q+ D G + Sbjct: 17 ARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVS 76 Query: 141 RQEVKQMVVATLAESGMNLKDTVI 164 +E + +++ +L ++G+ ++ + Sbjct: 77 LEEYEDLIIKSLQKAGIRVEKQSL 100 >1W7I-B nrPDB Length = 151 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 55/154 (35%), Gaps = 17/154 (11%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFD-LFDTKHNGILG 103 E + +ELF ++ I L ++ + N + + + D + + Sbjct: 10 EEFKEAFELFDRVGDGKI---LYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVD 66 Query: 104 FEEFARALSVF---HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK 160 FE F L +D + F+++D + G + E++ ++ L Sbjct: 67 FETFLPMLQAVAKNRGQGTYEDYLE-GFRVFDKEGNGKVMGAELRHVLTT--------LG 117 Query: 161 DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + E+ ++ +G I+ E + +L Sbjct: 118 EKMTEEEVETVLA-GHEDSNGCINYEAFLKHILS 150 >3I5H-B nrPDB Length = 153 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 53/142 (37%), Gaps = 13/142 (9%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDL 93 E R S +++ L E F I DG I E+ + +F + + D + Sbjct: 2 EEAPRRVKLSQRQMQELKEAFTMID--QDRDGFIGMEDLK-DMFSSLGRVPP--DDELNA 56 Query: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 + G L F F +D + +F ++D QGFI +K ++ Sbjct: 57 MLKECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLL----- 111 Query: 154 ESGMNLKDTVIEDIIDKTFEEA 175 N+ D ++ I +++A Sbjct: 112 ---ENMGDNFSKEEIKNVWKDA 130 Score = 33.9 bits (76), Expect = 0.056, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 29/90 (32%), Gaps = 25/90 (27%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMV-------------------------VATLAESG 156 ++ +F + D + GFI +++K M A L G Sbjct: 16 QELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLKECPGQLNFTAFLTLFG 75 Query: 157 MNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 + T ED + F D G I ++ Sbjct: 76 EKVSGTDPEDALRNAFSMFDEDGQGFIPED 105 >1F55-A nrPDB Length = 77 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 30/72 (41%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F L+D G I E+ ++ + L + E ++ E D + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRS--------LGLSPSEAEVNDLMNEIDVDGNHQ 62 Query: 183 IDKEEWRSLVLR 194 I+ E+ +L+ R Sbjct: 63 IEFSEFLALMSR 74 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 8/79 (10%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTK 97 T ++E + + LF K ++G I+ E + + E+ D + ++ D Sbjct: 5 TEEQIAEFKEAFALFDKD-----NNGSISSSELATVMRSLGLSPSEAEVNDLMNEI-DVD 58 Query: 98 HNGILGFEEFARALSVFHP 116 N + F EF +S Sbjct: 59 GNHQIEFSEFLALMSRQLK 77 >4MSP-A nrPDB Length = 200 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 30/64 (46%) Query: 125 HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKID 184 H SFQ DL + + EVK + + G + ++ + +++ F++ D DG I Sbjct: 130 HESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFIS 189 Query: 185 KEEW 188 E+ Sbjct: 190 AREF 193 >5XND-A nrPDB Length = 114 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 10/98 (10%) Query: 97 KHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESG 156 K G ++F +A + + D++ +F + D + GFIE +E+K L Sbjct: 25 KAAGSFDHKKFFKACGL---SGKSTDEVKKAFAIIDQDKSGFIEEEELK------LFLQN 75 Query: 157 MNLKDTVIEDIIDKTFEEA-DTKHDGKIDKEEWRSLVL 193 + D K F +A D+ DGKI +E+ +++ Sbjct: 76 FKAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIK 113 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 29/74 (39%), Gaps = 9/74 (12%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLF----DTKH 98 S E++ + + + G I +EE +L L +D F D+ Sbjct: 45 STDEVKKAFAIIDQD-----KSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDG 99 Query: 99 NGILGFEEFARALS 112 +G +G +EFA + Sbjct: 100 DGKIGIDEFAAMIK 113 Score = 30.8 bits (68), Expect = 0.47, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 29/92 (31%), Gaps = 3/92 (3%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFH--PN 117 G + ++F + K + + F + D +G + EE L F Sbjct: 23 GCKAAGSFDHKKF-FKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGAR 81 Query: 118 APIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 A D + + D G I E M+ Sbjct: 82 ALSDAETKAFLKAGDSDGDGKIGIDEFAAMIK 113 >1TRF-A nrPDB Length = 76 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F ++D G I +E+ ++ G N ++ +D EE D G Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMR----MLGQNPT----KEELDAIIEEVDEDGSGT 61 Query: 183 IDKEEWRSLVLR 194 ID EE+ +++R Sbjct: 62 IDFEEFLVMMVR 73 Score = 40.0 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 8/75 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E +A +++F G I+ +E + N + D + + D +G Sbjct: 8 IAEFKAAFDMFDADG-----GGDISTKELGTVMRMLGQNPTKEEL-DAIIEEVDEDGSGT 61 Query: 102 LGFEEFARALSVFHP 116 + FEEF + Sbjct: 62 IDFEEFLVMMVRQMK 76 Score = 33.1 bits (74), Expect = 0.10, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 24/59 (40%), Gaps = 1/59 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 FD+FD G + +E + P +++ + D G I+ +E M+V Sbjct: 15 FDMFDADGGGDISTKELGTVM-RMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMV 72 >1TNP-A nrPDB Length = 90 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 + +F ++D G I +E+ ++ G N ++ +D EE D G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMR----MLGQNPT----KEELDAIIEEVDEDGSGT 72 Query: 183 IDKEEWRSLVLR 194 ID EE+ +++R Sbjct: 73 IDFEEFLVMMVR 84 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 29/76 (38%), Gaps = 8/76 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 ++E +A +++F G I+ +E + N + D + + D +G Sbjct: 19 IAEFKAAFDMFDADG-----GGDISTKELGTVMRMLGQNPTKEEL-DAIIEEVDEDGSGT 72 Query: 102 LGFEEFARALSVFHPN 117 + FEEF + Sbjct: 73 IDFEEFLVMMVRQMKE 88 Score = 33.9 bits (76), Expect = 0.060, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FD+FD G + +E + P +++ + D G I+ +E M+V Sbjct: 26 FDMFDADGGGDISTKELGTVM-RMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVR 84 Query: 151 TLAE 154 + E Sbjct: 85 QMKE 88 >3TZ1-A nrPDB Length = 74 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 39/75 (52%), Gaps = 8/75 (10%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 + ++ +F++ D +++G I+ ++ ++ + L D + ED I+ E DT Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKS--------LGDELTEDEIENMIAETDTDGS 57 Query: 181 GKIDKEEWRSLVLRH 195 G +D EE++ L++ Sbjct: 58 GTVDYEEFKCLMMSS 72 Score = 31.2 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 26/69 (37%), Gaps = 4/69 (5%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 E++ + + K VI ++ + L E + + + DT +G + Sbjct: 5 DERELKEAFRVLDKEKKGVIK---VDVLRWILKSLGDELTEDEIENMIAET-DTDGSGTV 60 Query: 103 GFEEFARAL 111 +EEF + Sbjct: 61 DYEEFKCLM 69 >5H53-C nrPDB Length = 153 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 21/157 (13%), Positives = 53/157 (33%), Gaps = 12/157 (7%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNG 100 FS + + E F +++ L TN + + + + + N Sbjct: 4 EFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNA 63 Query: 101 I-LGFEEFARALSVFHPNAP--IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 + FE+F L N + +++D + G + E++ ++ Sbjct: 64 KKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT------- 116 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 L + + E+ ++ +G I+ E + ++ Sbjct: 117 -LGEKMKEEEVE-ALMAGQEDSNGCINYEAFVKHIMS 151 >1H4B-A nrPDB Length = 84 Score = 46.6 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 27/73 (36%), Gaps = 9/73 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ +D G I E+ + + + + D + E DT DG I +E Sbjct: 15 FKRFDANGDGKISAAELGEALKTLGSITP---------DEVKHMMAEIDTDGDGFISFQE 65 Query: 188 WRSLVLRHPSLLK 200 + + LLK Sbjct: 66 FTDFGRANRGLLK 78 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 26/72 (36%), Gaps = 2/72 (2%) Query: 79 TNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGF 138 + ++ +R+F FD +G + E AL P + K + D GF Sbjct: 3 DHPQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMA--EIDTDGDGF 60 Query: 139 IERQEVKQMVVA 150 I QE A Sbjct: 61 ISFQEFTDFGRA 72 >2M8U-A nrPDB Length = 77 Score = 46.6 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 33/69 (47%), Gaps = 8/69 (11%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 ++ +F+++D G++ +++++ L D + D I++ EAD ++ G Sbjct: 12 QVIEAFKVFDRDGNGYVTVDYLRKVLN--------ELGDMMPADEIEEMIYEADPQNSGY 63 Query: 183 IDKEEWRSL 191 + E + + Sbjct: 64 VQYETFVGM 72 >2N7L-C nrPDB Length = 141 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 38/84 (45%), Gaps = 9/84 (10%) Query: 112 SVFHPNAPIDDKIHFSFQLYDLK-QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK 170 +V ++ +F ++ L + G I +E+ +++ G N ++++ID Sbjct: 23 AVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMR----MLGQNPTPEELQEMID- 77 Query: 171 TFEEADTKHDGKIDKEEWRSLVLR 194 E D G +D +E+ +++R Sbjct: 78 ---EVDEDGSGTVDFDEFLVMMVR 98 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 35/86 (40%), Gaps = 10/86 (11%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L + +E +A +++F +DG I+ +E + + N + + Sbjct: 25 EQLTEEQ---KNEFKAAFDIFV----LGAEDGSISTKELGKVMRMLGQNPTPEELQEMID 77 Query: 92 DLFDTKHNGILGFEEFARALSVFHPN 117 ++ D +G + F+EF + + Sbjct: 78 EV-DEDGSGTVDFDEFLVMMVRXMKD 102 Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 38/102 (37%), Gaps = 3/102 (2%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKH-NGILGFEEFARALSVFHPNA 118 ++ G ++ T ++++ F FD+F +G + +E + + Sbjct: 9 GLVPRGSMDDIYKAAVEQLTEEQKNEFK-AAFDIFVLGAEDGSISTKELGKVM-RMLGQN 66 Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK 160 P +++ D G ++ E M+V + + NL Sbjct: 67 PTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMKDDSENLY 108 >3DTP-E nrPDB Length = 196 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 63/153 (41%), Gaps = 14/153 (9%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 F+ +++ E F+ I DG I+K + + A F + + L ++ D + G Sbjct: 51 FTQHQVQEFKEAFQLID--QDKDGFISKNDIR-ATFDSLGR--LCTEQELDSMVAEAPGP 105 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F F +D I +F L+D + G + + +K+ + + Sbjct: 106 INFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTW--------GE 156 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 +D +D+ EA +G ID +++ ++ + Sbjct: 157 KFSQDEVDQALSEAPIDGNGLIDIKKFAQILTK 189 >2KYF-A nrPDB Length = 108 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 + ++ F++ D Q GFIE E+K + ESG + + AD Sbjct: 36 SKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQ--RFESGARV---LTASETKTFLAAAD 90 Query: 177 TKHDGKIDKEEWRSLVLR 194 DGKI EE++ +V Sbjct: 91 HDGDGKIGAEEFQEMVQS 108 Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 2/79 (2%) Query: 74 LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI--DDKIHFSFQLY 131 + +KK S +F + D +G + +E L F A + + Sbjct: 30 FQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAA 89 Query: 132 DLKQQGFIERQEVKQMVVA 150 D G I +E ++MV + Sbjct: 90 DHDGDGKIGAEEFQEMVQS 108 >4D1E-A nrPDB Length = 876 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 51/116 (43%), Gaps = 7/116 (6%) Query: 34 ELLARDT-VFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRV 90 ++L RD + ++ F +GL++ E+F+ L + E+ FA R+ Sbjct: 723 QILTRDAKGITQEQMNEFRASFNHFDR--RKNGLMDHEDFRACLISMGYDLGEAEFA-RI 779 Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 L D G + F+ F ++ + +++ SF++ + +I +E+++ Sbjct: 780 MTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP-YILAEELRR 834 Score = 36.6 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 11/75 (14%), Positives = 27/75 (36%), Gaps = 8/75 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++ SF +D ++ G ++ ++ A L G +L + + D G Sbjct: 738 NEFRASFNHFDRRKNGLMDHED----FRACLISMGYDLGEAEFA----RIMTLVDPNGQG 789 Query: 182 KIDKEEWRSLVLRHP 196 + + + + R Sbjct: 790 TVTFQSFIDFMTRET 804 >5VLN-A nrPDB Length = 120 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 38/85 (44%), Gaps = 9/85 (10%) Query: 112 SVFHPNAPIDDKIHFSFQLYDLK-QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK 170 +V ++ +F ++ L + G I +E+ +++ G N ++++ID Sbjct: 8 AVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMR----MLGQNPTPEELQEMID- 62 Query: 171 TFEEADTKHDGKIDKEEWRSLVLRH 195 E D G +D +E+ +++R Sbjct: 63 ---EVDEDGSGTVDFDEFLVMMVRS 84 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 35/86 (40%), Gaps = 10/86 (11%) Query: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 E L + +E +A +++F +DG I+ +E + + N + + Sbjct: 10 EQLTEEQ---KNEFKAAFDIFV----LGAEDGSISTKELGKVMRMLGQNPTPEELQEMID 62 Query: 92 DLFDTKHNGILGFEEFARALSVFHPN 117 ++ D +G + F+EF + + Sbjct: 63 EV-DEDGSGTVDFDEFLVMMVRSMKD 87 >1IJ5-A nrPDB Length = 323 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 63/149 (42%), Gaps = 18/149 (12%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFE 105 ++ AL F+KI + +G ++++EF+ + + D +F D + +GF Sbjct: 186 DLAALVADFRKIDTN--SNGTLSRKEFREHFVRLGFDKKSVQDALFRYADEDESDDVGFS 243 Query: 106 EFAR-ALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVI 164 E+ L + I ++F D + G + ++EV++++ ++ ++ Sbjct: 244 EYVHLGLCLLVLR------ILYAFA--DFDKSGQLSKEEVQKVLE------DAHIPESAR 289 Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + + F D + +E+ LVL Sbjct: 290 KKF-EHQFSVVDVDDSKSLSYQEFVMLVL 317 >4P5W-A nrPDB Length = 411 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 49/121 (40%), Gaps = 8/121 (6%) Query: 74 LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDL 133 L +F ++ + + + D +G++ F+EF SV D +FQL+D Sbjct: 67 LNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCA---PDALFMVAFQLFDK 123 Query: 134 KQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 +G + ++VKQ+ T ++ + + F + +H + E+ +L Sbjct: 124 AGKGEVTFEDVKQVFGQTTIH--QHIPFNWDSEFVQLHFGKERKRH---LTYAEFTQFLL 178 Query: 194 R 194 Sbjct: 179 E 179 >1SJJ-A nrPDB Length = 863 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 46/103 (44%), Gaps = 9/103 (8%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNGILG 103 E A + F + G+++ E+F+ L N E+ FA R+ + D G++ Sbjct: 726 EFRASFNHFDR-----KKTGMMDCEDFRACLISMGYNMGEAEFA-RIMSIVDPNRMGVVT 779 Query: 104 FEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 F+ F +S + D++ SF++ + +I E+++ Sbjct: 780 FQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITVDELRR 821 Score = 33.5 bits (75), Expect = 0.079, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 27/75 (36%), Gaps = 8/75 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++ SF +D K+ G ++ ++ A L G N+ + + D G Sbjct: 725 NEFRASFNHFDRKKTGMMDCED----FRACLISMGYNMGEAEFA----RIMSIVDPNRMG 776 Query: 182 KIDKEEWRSLVLRHP 196 + + + + R Sbjct: 777 VVTFQAFIDFMSRET 791 >1GGW-A nrPDB Length = 140 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 22/156 (14%), Positives = 58/156 (37%), Gaps = 21/156 (13%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 S + + LF + + I I L N + + ++ + Sbjct: 3 DDSPYKQAFSLFDRHGTGRIPKTSIGDL---LRACGQNPTLAEITE-----IESTLPAEV 54 Query: 103 GFEEFARALSV---FHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 E+F + L+ F ++ + FQ++D G I E++ ++ + G L Sbjct: 55 DMEQFLQVLNRPNGFDMPGDPEEFVK-GFQVFDKDATGMIGVGELRYVLTSL----GEKL 109 Query: 160 KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 + +++++ + DG ++ ++ ++L + Sbjct: 110 SNEEMDELLKGVPVK-----DGMVNYHDFVQMILAN 140 >5E1J-A nrPDB Length = 741 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 39/97 (40%), Gaps = 13/97 (13%) Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 + +F L D + G I++ Q + + + ++ F+E D D KI Sbjct: 327 LEKAFGLIDSDKNGEIDKN---QCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKI 383 Query: 184 DKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFH 220 +K+E+ L + + L++ K+ PS H Sbjct: 384 NKDEFADLC-------QAIALRFQKE---EVPSLFEH 410 Score = 32.7 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 33/103 (32%), Gaps = 4/103 (3%) Query: 69 KEEFQLALFKTNKKESLFADRVFDLFDTKHNGILG----FEEFARALSVFHPNAPIDDKI 124 KE+ + ++ + ++ F L D+ NG + + F + + ++ Sbjct: 309 KEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEF 368 Query: 125 HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 F D + I + E + A ++ E Sbjct: 369 GLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHF 411 >1JF0-A nrPDB Length = 195 Score = 45.0 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Query: 85 LFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 + D VFD+FD +G + +E+ +A +P ++ +FQ DL G ++ E+ Sbjct: 113 EWGDAVFDIFDKDGSGTITLDEW-KAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEM 171 Query: 145 KQ 146 + Sbjct: 172 TR 173 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 8/60 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F ++D G I E A SG++ E+ +KTF+ D + G++D +E Sbjct: 119 FDIFDKDGSGTITLDE----WKAYGRISGISPS----EEDCEKTFQHCDLDNSGELDVDE 170 Score = 34.3 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 42/130 (32%), Gaps = 14/130 (10%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARA--------LSVFHPNAPIDDKI 124 +L N K +FD D NG + +E L Sbjct: 8 KLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDC 67 Query: 125 HFSF-QLYDLKQQGFIERQEVKQ----MVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 +F + L+ + E + + A LA+ N T+I + D F+ D Sbjct: 68 VEAFFRGCGLEYGKETKFPEFLEGWKNLANADLAKWARNEP-TLIREWGDAVFDIFDKDG 126 Query: 180 DGKIDKEEWR 189 G I +EW+ Sbjct: 127 SGTITLDEWK 136 Score = 26.9 bits (58), Expect = 7.4, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 10/25 (40%) Query: 171 TFEEADTKHDGKIDKEEWRSLVLRH 195 F+ D +G+I +E S Sbjct: 25 MFDYLDINGNGQITLDEIVSKASDD 49 >1I84-U nrPDB Length = 166 Score = 45.0 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 F +EIE E F I DG+I+K++ + F + ++ + + D + +G Sbjct: 19 FDETEIEDFKEAFTVIDQNA--DGIIDKDDLR-ETFAAMGRLNVKNEEL-DAMIKEASGP 74 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F F A +D I +F++ D +G I++ +++++ G Sbjct: 75 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTT----GGGRFTP 130 Query: 162 TVIEDI 167 I+++ Sbjct: 131 EEIKNM 136 Score = 31.6 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 28/95 (29%), Gaps = 26/95 (27%) Query: 115 HPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT----------------------- 151 + + +F + D G I++ ++++ A Sbjct: 18 MFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPINF 77 Query: 152 ---LAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 L G LK ED+I F+ D G I Sbjct: 78 TVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSI 112 >6EAZ-A nrPDB Length = 379 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 49/129 (37%), Gaps = 15/129 (11%) Query: 95 DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 D G++ + E+ L++ H +F++ D+ IER+E ++ + Sbjct: 95 DLGDKGVISYTEYLFLLTILT---KPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQ 151 Query: 155 SGMNLKDTVIEDIIDKTFEEADTK-----------HDGKIDKEEWRSLVLRHPSLLKNMT 203 G T + D T +E + K+ +E+R + + ++ M Sbjct: 152 DGFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEME 211 Query: 204 -LQYLKDIT 211 LQ+ K + Sbjct: 212 FLQFSKGLN 220 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 48/109 (44%), Gaps = 7/109 (6%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFADRVFDLFDTKHNG 100 F+ +E + +Y + +V + I+ +EF+ F T+ ++ A ++F L + Sbjct: 234 FTNTENKDIYWRNVREKLSVGES--ISLDEFKSFCHFTTHLEDFAIAMQMFSL----AHR 287 Query: 101 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + EF RA+ V D+ + F+++DL + E ++ Sbjct: 288 PVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLK 336 >3PAT-A nrPDB Length = 110 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 9/109 (8%) Query: 87 ADRVFDLFDT-KHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 AD + D K G ++F + + +A + + F+ D GFIE +E+K Sbjct: 9 ADDIKKALDAVKAEGSFNHKKFFALVGLKAMSA---NDVKKVFKAIDADASGFIEEEELK 65 Query: 146 QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ + A+ + + + AD DGKI +E+ +LV Sbjct: 66 FVLKSFAAD-----GRDLTDAETKAFLKAADKDGDGKIGIDEFETLVHE 109 Score = 36.6 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 3/96 (3%) Query: 55 KKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVF 114 KK AV +G N ++F AL + +VF D +G + EE L F Sbjct: 13 KKALDAVKAEGSFNHKKF-FALVGLKAMSANDVKKVFKAIDADASGFIEEEELKFVLKSF 71 Query: 115 HPNA-PIDDKIHFSF-QLYDLKQQGFIERQEVKQMV 148 + + D +F + D G I E + +V Sbjct: 72 AADGRDLTDAETKAFLKAADKDGDGKIGIDEFETLV 107 >2N8Y-A nrPDB Length = 153 Score = 44.7 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 41/107 (38%), Gaps = 12/107 (11%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALF------KTNKKESLFADRVFDLFDTKHN 99 E A + F + G + EEF+ L + + R+ + D Sbjct: 11 EFRASFNHFDRD-----HSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRL 65 Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 G++ F+ F +S + D++ SF++ + +I E+++ Sbjct: 66 GVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRR 111 Score = 34.3 bits (77), Expect = 0.040, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 26/75 (34%), Gaps = 3/75 (4%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 ++ SF +D G + +E K +++ + G D E + D G Sbjct: 10 NEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGN---DPQGEAEFARIMSIVDPNRLG 66 Query: 182 KIDKEEWRSLVLRHP 196 + + + + R Sbjct: 67 VVTFQAFIDFMSRET 81 >1QX2-A nrPDB Length = 76 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 35/78 (44%), Gaps = 8/78 (10%) Query: 119 PIDDKIHFSFQLYDLKQQ--GFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 ++I +F+++ K+ I ++E+K ++ + +D+ EE D Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMST------LDEMIEEVD 55 Query: 177 TKHDGKIDKEEWRSLVLR 194 DG++ EE+ ++ + Sbjct: 56 KNGDGEVSFEEFLVMMKK 73 Score = 34.6 bits (78), Expect = 0.035, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNK---KESLFADRVFDLFDTKHN 99 S EI+ +E+F ++ D I+KEE +L + K D + + D + Sbjct: 3 SPEEIKGAFEVF---AAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGD 59 Query: 100 GILGFEEFARALSVFH 115 G + FEEF + Sbjct: 60 GEVSFEEFLVMMKKIS 75 >1O1A-B nrPDB Length = 145 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI 101 F +EIE E F I DG+I+K++ + F + ++ + + D + +G Sbjct: 1 FDETEIEDFKEAFTVIDQNA--DGIIDKDDLR-ETFAAMGRLNVKNEEL-DAMIKEASGP 56 Query: 102 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 + F F A +D I +F++ D +G I++ +++++ G Sbjct: 57 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTT----GGGRFTP 112 Query: 162 TVIEDI 167 I+++ Sbjct: 113 EEIKNM 118 Score = 30.8 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 27/88 (30%), Gaps = 26/88 (29%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVAT--------------------------LAES 155 + +F + D G I++ ++++ A L Sbjct: 7 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPINFTVFLTMF 66 Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKI 183 G LK ED+I F+ D G I Sbjct: 67 GEKLKGADPEDVIMGAFKVLDPDGKGSI 94 >3LCP-C nrPDB Length = 93 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN----LKDTVIEDIIDKTFEE 174 P + ++H+ F+++D ++ E+ + E G + + + +IID + Sbjct: 16 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 74 Query: 175 ADTKHDGKIDKEEWRSLVL 193 D +DG ID E+ + Sbjct: 75 DDKNNDGYIDYAEFAKSLQ 93 >2VRG-A nrPDB Length = 124 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN----LKDTVIEDIIDKTFEE 174 P + ++H+ F+++D ++ E+ + E G + + + +IID + Sbjct: 47 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 105 Query: 175 ADTKHDGKIDKEEWRSLVL 193 D +DG ID E+ + Sbjct: 106 DDKNNDGYIDYAEFAKSLQ 124 >3A4U-B nrPDB Length = 143 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN----LKDTVIEDIIDKTFEE 174 P + ++H+ F+++D ++ E+ + E G + + + +IID + Sbjct: 66 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 124 Query: 175 ADTKHDGKIDKEEWRSLVL 193 D +DG ID E+ + Sbjct: 125 DDKNNDGYIDYAEFAKSLQ 143 >5TBY-E nrPDB Length = 166 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 60/154 (38%), Gaps = 18/154 (11%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQ---LALFKTNKKESLFADRVFDLFDTKH 98 F ++I+ E F + DG I+K + + AL + N K + + + Sbjct: 21 FEQTQIQEFKEAFTIMDQN--RDGFIDKNDLRDTFAALGRVNVKNEEIDEMI-----KEA 73 Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 G + F F A ++ I +F+++D + +G ++ V++M+ Sbjct: 74 PGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQ------- 126 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + ++ +D+ F G +D + ++ Sbjct: 127 -AERFSKEEVDQMFAAFPPDVTGNLDYKNLVHII 159 >3KPX-A nrPDB Length = 198 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 67 INKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHF 126 + K + +L + + VFD+FD +G + +E+ + P D+ Sbjct: 98 LAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEW-KTYGGISGICPSDEDAEK 156 Query: 127 SFQLYDLKQQGFIERQEVKQ 146 +F+ DL G ++ E+ + Sbjct: 157 TFKHCDLDNSGKLDVDEMTR 176 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 8/60 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F ++D G I E SG+ D + +KTF+ D + GK+D +E Sbjct: 122 FDIFDKDGSGSISLDE----WKTYGGISGICPSD----EDAEKTFKHCDLDNSGKLDVDE 173 Score = 33.9 bits (76), Expect = 0.062, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 26/72 (36%), Gaps = 2/72 (2%) Query: 125 HFSFQLYDLKQQGFIERQE-VKQMVVATLAESGMNLKDTVI-EDIIDKTFEEADTKHDGK 182 F F D+ G I E V + A+ G T ++ ++ F++ + + Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKE 85 Query: 183 IDKEEWRSLVLR 194 ++ + + Sbjct: 86 VEFPAFVNGWKE 97 Score = 31.2 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 41/130 (31%), Gaps = 14/130 (10%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFA--------RALSVFHPNAPIDDKI 124 +L + K +F+ D NG + +E L + Sbjct: 11 KLKTNFEDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEA 70 Query: 125 HFSF-QLYDLKQQGFIER----QEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 +F + L +E K++ L N K ++I + + F+ D Sbjct: 71 VEAFFKKIGLDYGKEVEFPAFVNGWKELAKHDLKLWSQN-KKSLIRNWGEAVFDIFDKDG 129 Query: 180 DGKIDKEEWR 189 G I +EW+ Sbjct: 130 SGSISLDEWK 139 >5TBY-C nrPDB Length = 195 Score = 43.5 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 53/160 (33%), Gaps = 14/160 (8%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKH 98 F+ +IE E F + I + L N ++ + + Sbjct: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 Query: 99 N-GILGFEEFARALSVFHPNAPID--DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAES 155 N ++ FE F L N + +++D + G + E++ ++ Sbjct: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT----- 159 Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 L + + ED ++K +G I+ E + ++ Sbjct: 160 ---LGERLTEDEVEKLMA-GQEDSNGCINYEAFVKHIMSS 195 >3JAX-C nrPDB Length = 151 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 24/156 (15%), Positives = 53/156 (33%), Gaps = 12/156 (7%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHN-G 100 FS + E F+ L ++ + N + + + + N Sbjct: 4 FSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLK 63 Query: 101 ILGFEEFARALSVFHPNAPID--DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 L FE+F + N + +++D + G + E++ ++V G Sbjct: 64 TLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTL----GEK 119 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + +E ++ +G I+ EE +VL Sbjct: 120 MTEEEVEQLV-----AGHEDSNGCINYEELVRMVLS 150 >6FSA-D nrPDB Length = 199 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 23/166 (13%), Positives = 57/166 (34%), Gaps = 14/166 (8%) Query: 32 DPELLARD-TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRV 90 DP + + T + E + + LF + + + L N ++ + Sbjct: 42 DPSKIKIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDV-LRALGQNPTQAEVLRVL 100 Query: 91 FDLFDTKHNG-ILGFEEFARALSVFHPNAPI--DDKIHFSFQLYDLKQQGFIERQEVKQM 147 + N ++ F+ F L N + +++D + G + E++ + Sbjct: 101 GKPKQEELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 160 Query: 148 VVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + L + + ED ++K +G I+ E + ++ Sbjct: 161 LAT--------LGEKLTEDEVEKLMA-GQEDSNGCINYEAFVKHIM 197 >4P5X-A nrPDB Length = 315 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 53/151 (35%), Gaps = 12/151 (7%) Query: 48 EALYELFKKISSAVID-DGLINKEEFQLALFKTNKKES---LFADRVFDLFDTKHNGILG 103 L +F + +S +D + + E+F + + + D +G++ Sbjct: 18 HELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLIS 77 Query: 104 FEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTV 163 ++EF SV D +FQL+D G + + VK++ T+ ++ Sbjct: 78 YQEFLAFESVLCA---PDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHH--HIPFNW 132 Query: 164 IEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + I F ++ E+ + Sbjct: 133 DCEFIRLHFG---HNRKKHLNYTEFTQFLQE 160 Score = 30.4 bits (67), Expect = 0.63, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 39/132 (29%), Gaps = 39/132 (29%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFE-------------- 105 DGLI+ +EF +S+F F LFD NG + FE Sbjct: 69 DQTKDGLISYQEFLAFESVLCAPDSMFI-VAFQLFDKSGNGEVTFENVKEIFGQTIIHHH 127 Query: 106 -------EFARALSVFHPNAPID---------------DKIHFSFQLYDLKQQGFIERQE 143 EF R F N + +F L D + G I + Sbjct: 128 IPFNWDCEFIRL--HFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLD 185 Query: 144 VKQMVVATLAES 155 ++V + Sbjct: 186 FSDIMVTIRSHM 197 >4L9M-A nrPDB Length = 559 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 38/97 (39%), Gaps = 20/97 (20%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ YD Q G+I ++E +++ + F D +G I ++E Sbjct: 431 FKNYDHDQDGYISQEEFEKIAASFPFS-----------------FCVMDKDREGLISRDE 473 Query: 188 WRSLVLRHPSLLKNMTLQY---LKDITTTFPSFVFHS 221 + +R S+ + L + ++ T P+F + Sbjct: 474 ITAYFMRASSIYSKLGLGFPHNFQETTYLKPTFCDNC 510 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 26/73 (35%), Gaps = 17/73 (23%) Query: 79 TNKKESLF-------ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLY 131 D VF +D +G + EEF + + F FSF + Sbjct: 412 PKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFP----------FSFCVM 461 Query: 132 DLKQQGFIERQEV 144 D ++G I R E+ Sbjct: 462 DKDREGLISRDEI 474 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 16/32 (50%) Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + ++D F+ D DG I +EE+ + P Sbjct: 424 QRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 >4YGB-B nrPDB Length = 104 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN----LKDTVIEDIIDKTFEE 174 P + ++H+ F+++D ++ E+ + E G + + + +IID + Sbjct: 27 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 85 Query: 175 ADTKHDGKIDKEEWRSLVL 193 D +DG ID E+ + Sbjct: 86 DDKNNDGYIDYAEFAKSLQ 104 >1B7T-Y nrPDB Length = 156 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 61/156 (39%), Gaps = 18/156 (11%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLA--LFKTNKKESLFADRVFDLFDTK 97 T +I+ + E F I V DG ++KE+ + + + + Sbjct: 10 TKLPQKQIQEMKEAFSMID--VDRDGFVSKEDIKAISEQLGRAPDDKELTAML-----KE 62 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 G L F F S ++ I +F ++D ++ + + +K ++ Sbjct: 63 APGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLL--------E 114 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 N+ D +D + TF+EA + GK D ++ +++ Sbjct: 115 NMGDNFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIK 149 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 38/99 (38%), Gaps = 14/99 (14%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK--------TFE 173 ++ +F + D+ + GF+ +++ + A + G D + ++ + F Sbjct: 18 QEMKEAFSMIDVDRDGFVSKED----IKAISEQLGRAPDDKELTAMLKEAPGPLNFTMFL 73 Query: 174 EADTKHDGKIDKEEWRS--LVLRHPSLLKNMTLQYLKDI 210 + D EE + K + ++Y+KD+ Sbjct: 74 SIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDL 112 >2HPS-A nrPDB Length = 186 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 ++D DT +G + EF L P+ DDK F D + G I R E V Sbjct: 107 MYDCIDTDKDGYVSLPEFKAFLQAVGPDLT-DDKAITCFNTLDFNKNGQISRDEFLVTVN 165 Score = 34.6 bits (78), Expect = 0.039, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 22/58 (37%), Gaps = 8/58 (13%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 D + G++ E K + A + +D F D +G+I ++E+ Sbjct: 112 DTDKDGYVSLPEFKAFLQAV--------GPDLTDDKAITCFNTLDFNKNGQISRDEFL 161 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 38/109 (34%), Gaps = 13/109 (11%) Query: 95 DTKHNGILGFEEF---------ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV- 144 D +G + E++ LS + + + QL L I +E Sbjct: 24 DVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQL-GLAPGVRISVEEAA 82 Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + L G VI+ +I ++ DT DG + E+++ + Sbjct: 83 VNATDSLLKMKGEEKAMAVIQSLI--MYDCIDTDKDGYVSLPEFKAFLQ 129 Score = 32.7 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 22/65 (33%), Gaps = 1/65 (1%) Query: 52 ELFKKISSAVIDDGLINKEEFQLALFKTNKK-ESLFADRVFDLFDTKHNGILGFEEFARA 110 L DG ++ EF+ L A F+ D NG + +EF Sbjct: 104 SLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVT 163 Query: 111 LSVFH 115 ++ F Sbjct: 164 VNDFL 168 >4GJF-A nrPDB Length = 89 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 37/84 (44%), Gaps = 9/84 (10%) Query: 112 SVFHPNAPIDDKIHFSFQLY-DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK 170 +V ++ +F ++ + G I +E+ +++ G N ++++ID Sbjct: 8 AVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMR----MLGQNPTPEELQEMID- 62 Query: 171 TFEEADTKHDGKIDKEEWRSLVLR 194 E D G +D +E+ +++R Sbjct: 63 ---EVDEDGSGTVDFDEFLVMMVR 83 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 34/80 (42%), Gaps = 7/80 (8%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTK 97 T +E +A +++F + +DG I+ +E + + N + + ++ D Sbjct: 13 TEEQKNEFKAAFDIFVQ----GAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEV-DED 67 Query: 98 HNGILGFEEFARALSVFHPN 117 +G + F+EF + + Sbjct: 68 GSGTVDFDEFLVMMVRCMKD 87 >3SIA-A nrPDB Length = 220 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 44/127 (34%), Gaps = 16/127 (12%) Query: 23 LYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKK 82 +Y+ + + + + +Y+ F + G + E + F + Sbjct: 26 IYQMPPSVRNTWWFPLLNTIPLDQYTRIYQWFMGVDRD--RSGTLEINELMMGQFPGGIR 83 Query: 83 ESL-FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLK---QQGF 138 S A R+ +FDT NG + F EF + ++ L+ + + G Sbjct: 84 LSPQTALRMMRIFDTDFNGHISFYEFMAMYKF----------MELAYNLFVMNARARSGT 133 Query: 139 IERQEVK 145 +E E+ Sbjct: 134 LEPHEIL 140 Score = 28.5 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 18/66 (27%), Gaps = 4/66 (6%) Query: 89 RVFDLF---DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 R++ F D +G L E + +++D G I E Sbjct: 52 RIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALR-MMRIFDTDFNGHISFYEFM 110 Query: 146 QMVVAT 151 M Sbjct: 111 AMYKFM 116 >4OKH-A nrPDB Length = 189 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 29/127 (22%), Positives = 37/127 (29%), Gaps = 30/127 (23%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + L DT +G L +EF KI F+ YD Q G I E++ V Sbjct: 60 MIALMDTDGSGKLNLQEF----HHLWNKIKAWQKI---FKHYDTDQSGTINSYEMRNAVN 112 Query: 150 ATLAESGMNLKDTVIEDIIDK---------------------TFEEADTKHDGKIDKE-- 186 L D + DK F D DG I Sbjct: 113 DAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVL 172 Query: 187 EWRSLVL 193 EW L + Sbjct: 173 EWLQLTM 179 >3AKA-A nrPDB Length = 166 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 33/91 (36%), Gaps = 11/91 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDT-------VIEDIIDKTFEEADTKHD 180 F +D G I+R + A LAE G+ + E + AD D Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRDGD 69 Query: 181 GKIDKEEWRSLVLR----HPSLLKNMTLQYL 207 +I +EE+ + ++ P + +L Sbjct: 70 QRITREEFVTGAVKRLRDKPDRFAEIARPFL 100 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 50/169 (29%), Gaps = 39/169 (23%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQ------LALFKT----------NKKESLFA 87 I A + F + +G I++ +F LA F Sbjct: 3 ERRIAARFTTFDQDG-----NGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALW 57 Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDK-------IHFSFQLYDLKQQGFIE 140 + + D + + EEF +V D +H + + D G + Sbjct: 58 QGLAGIADRDGDQRITREEFVTG-AVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVT 116 Query: 141 RQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + + + A V ED+ + DT DGK+ + E Sbjct: 117 VADTARALTAF----------GVPEDLARQAAAALDTDGDGKVGETEIV 155 >1QXP-A nrPDB Length = 900 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 69/197 (35%), Gaps = 45/197 (22%) Query: 25 KQSGGLGDPELLARDTV----FSVSEIEALYE-LFKKISSAVIDDGLINKEEFQLAL--- 76 K++G + + + S EI+ ++ LF K++ ++ I+ +E Q L Sbjct: 506 KKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDME---ISVKELQTILNRI 562 Query: 77 ------FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQL 130 +TN + +L D NG LG EF + I F+ Sbjct: 563 ISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTI-------FRK 615 Query: 131 YDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID--------------------- 169 +DL + G + E++ + A + L ++ D Sbjct: 616 FDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILF 675 Query: 170 KTFEEADTKHDGKIDKE 186 K F++ D ++ G I + Sbjct: 676 KIFKQLDPENTGTIQLD 692 Score = 35.0 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 38/127 (29%), Gaps = 30/127 (23%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV----- 144 + + D+ G LGFEEF + K ++ ++ + G I E+ Sbjct: 779 MVAVMDSDTTGKLGFEEFKYLWNNI-------KKWQGIYKRFETDRSGTIGSNELPGAFE 831 Query: 145 ---KQMVVATLAESGMNLKDTVIEDIID-------------KTFEEADTKHDGKI--DKE 186 + + D D + F D G+I + + Sbjct: 832 AAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQ 891 Query: 187 EWRSLVL 193 EW L + Sbjct: 892 EWLQLTM 898 Score = 34.6 bits (78), Expect = 0.031, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 41/110 (37%), Gaps = 4/110 (3%) Query: 82 KESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQ-LYDL--KQQGF 138 + + D + F K G ++ +A ++ +++I +F+ L+ Sbjct: 491 EPNKEGDFLLRFFSEKKAGTQELDDQIQA-NLPDEKVLSEEEIDDNFKTLFSKLAGDDME 549 Query: 139 IERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 I +E++ ++ +++ + + D +GK+ E+ Sbjct: 550 ISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEF 599 >5ZH6-A nrPDB Length = 107 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 D + F + D + GFIE E+K ++ + E + D+ Sbjct: 37 KSDANLAKVFDILDQDRSGFIEVDELK-----LFLQNFSATARELDETETNAFLAAGDSD 91 Query: 179 HDGKIDKEEWRSLVL 193 HDGKI +E++++V Sbjct: 92 HDGKIGVDEFKAMVK 106 Score = 34.6 bits (78), Expect = 0.030, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 3/88 (3%) Query: 65 GLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA-PIDDK 123 G N + F + TNK ++ A +VFD+ D +G + +E L F A +D+ Sbjct: 21 GSFNHKTFFVTSGLTNKSDANLA-KVFDILDQDRSGFIEVDELKLFLQNFSATARELDET 79 Query: 124 IHFSF-QLYDLKQQGFIERQEVKQMVVA 150 +F D G I E K MV A Sbjct: 80 ETNAFLAAGDSDHDGKIGVDEFKAMVKA 107 >2OS8-B nrPDB Length = 157 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 27/156 (17%), Positives = 56/156 (35%), Gaps = 18/156 (11%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTK 97 T +I+ + E F I DG I+ + + + + + + Sbjct: 11 TKLPQKQIQEMKEAFTMIDQN--RDGFIDINDLKEMFSSLGRTPDDKELTAML-----KE 63 Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 G L F F S ++ I +F ++D + + +K ++ Sbjct: 64 APGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLL--------E 115 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 N+ D +D + TF+EA + GK D + +++ Sbjct: 116 NMGDNFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIK 150 Score = 31.9 bits (71), Expect = 0.21, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 36/95 (37%), Gaps = 6/95 (6%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID----KTFEEADT 177 ++ +F + D + GFI+ ++K+M + ++++ F + Sbjct: 19 QEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNFTMFLSIFS 78 Query: 178 KHDGKIDKEEWRSLV--LRHPSLLKNMTLQYLKDI 210 D EE + K + ++Y+KD+ Sbjct: 79 DKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDL 113 >1A75-A nrPDB Length = 108 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 5/77 (6%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 + D I +F D + GFIE E+K + + L D + + D Sbjct: 36 SGKSADDIKKAFVFIDQDKSGFIEEDELK-LFLQVFKAGARALTDAETK----AFLKAGD 90 Query: 177 TKHDGKIDKEEWRSLVL 193 + DG I EEW +LV Sbjct: 91 SDGDGAIGVEEWVALVK 107 Score = 30.8 bits (68), Expect = 0.49, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 20/58 (34%), Gaps = 4/58 (6%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSV 113 G I ++E +L L D F D+ +G +G EE+ + Sbjct: 51 DQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSDGDGAIGVEEWVALVKA 108 Score = 27.3 bits (59), Expect = 4.8, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 28/87 (32%), Gaps = 6/87 (6%) Query: 70 EEFQLALFKTN-KKESLFADRVFDLF---DTKHNGILGFEEFARALSVFHP--NAPIDDK 123 + F F AD + F D +G + +E L VF A D + Sbjct: 22 DSFSYKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAE 81 Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVA 150 + D G I +E +V A Sbjct: 82 TKAFLKAGDSDGDGAIGVEEWVALVKA 108 >2KQY-A nrPDB Length = 108 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 5/82 (6%) Query: 112 SVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKT 171 S ++ D+I F + D + GFIE +E++ + + + + Sbjct: 31 STVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAET-----KAF 85 Query: 172 FEEADTKHDGKIDKEEWRSLVL 193 DT DGKI EE++SLV Sbjct: 86 LAAGDTDGDGKIGVEEFQSLVK 107 Score = 29.6 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 21/58 (36%), Gaps = 4/58 (6%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSV 113 G I +EE QL L + + F DT +G +G EEF + Sbjct: 51 DQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKIGVEEFQSLVKA 108 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%), Gaps = 2/64 (3%) Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAPI--DDKIHFSFQLYDLKQQGFIERQEVKQ 146 +VF + D +G + EE L F +A + + D G I +E + Sbjct: 45 KVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKIGVEEFQS 104 Query: 147 MVVA 150 +V A Sbjct: 105 LVKA 108 >1S36-A nrPDB Length = 195 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 85 LFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 + D VFD+FD +G + +E+ +A +P + +F+ DL G ++ E+ Sbjct: 113 EWGDAVFDIFDKDGSGTITLDEW-KAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEM 171 Query: 145 KQ 146 + Sbjct: 172 TR 173 Score = 34.6 bits (78), Expect = 0.030, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 42/134 (31%), Gaps = 22/134 (16%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFA--------RALSVFHPNAPIDDKI 124 +L N + +FD D NG + +E L Sbjct: 8 KLKTDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVC 67 Query: 125 HFSFQLYDLKQQGFIERQEV---------KQMVVATLAESGMNLKDTVIEDIIDKTFEEA 175 +F + G +E+ KQ+ + L + N T+I + D F+ Sbjct: 68 VEAF----FRGCGMEYGKEIAFPQFLDGFKQLATSELKKWARNEP-TLIREWGDAVFDIF 122 Query: 176 DTKHDGKIDKEEWR 189 D G I +EW+ Sbjct: 123 DKDGSGTITLDEWK 136 >5Z1Q-A nrPDB Length = 95 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 32/74 (43%), Gaps = 8/74 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +I +F L+D + G I+ E+K + A L V + I + E D + +G Sbjct: 27 QEIKEAFDLFDTNKTGSIDYHELKVAMRA--------LGFDVKKPEILELMNEYDREGNG 78 Query: 182 KIDKEEWRSLVLRH 195 I +++ ++ Sbjct: 79 YIGFDDFLDIMTEK 92 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FDLFDT G + + E A+ + + I YD + G+I + ++ Sbjct: 33 FDLFDTNKTGSIDYHELKVAMRALGFDVKKPE-ILELMNEYDREGNGYIGFDDFLDIMTE 91 Query: 151 TLA 153 + Sbjct: 92 KIK 94 Score = 35.0 bits (79), Expect = 0.023, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 40/94 (42%), Gaps = 11/94 (11%) Query: 26 QSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKE 83 Q + L+ + EI+ ++LF G I+ E ++A+ + K+ Sbjct: 11 QPPKKRVRQELSEEQ---KQEIKEAFDLFDT-----NKTGSIDYHELKVAMRALGFDVKK 62 Query: 84 SLFADRVFDLFDTKHNGILGFEEFARALSVFHPN 117 + + + +D + NG +GF++F ++ N Sbjct: 63 PEILELMNE-YDREGNGYIGFDDFLDIMTEKIKN 95 >3I5I-C nrPDB Length = 159 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 50/159 (31%), Gaps = 8/159 (5%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHN 99 + + EIE + E+F DG ++ + L + Sbjct: 1 SQLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTKKMGE 60 Query: 100 GILGFEEFARALSVFHPN--APIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 EE D+ +F+ +D + QG I E++ ++ G Sbjct: 61 KAYKLEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLK----MLGE 116 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 + + DI TF + DG I E+ V+ P Sbjct: 117 RITEDQCNDIF--TFCDIREDIDGNIKYEDLMKKVMAGP 153 >5XOP-A nrPDB Length = 66 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 25/64 (39%), Gaps = 8/64 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ D+ G + +EVK V A E ++ F+ D DG ID EE Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKN--------EQLLQLIFKSIDKDGDGFIDFEE 57 Query: 188 WRSL 191 + Sbjct: 58 FAKF 61 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 A+ +F D +G + +EE +S + + F+ D GFI+ +E Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN-EQLLQLIFKSIDKDGDGFIDFEE 57 Score = 33.9 bits (76), Expect = 0.062, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 60 AVIDDGLINKEEFQLALFKTNK-KESLFADRVFDLFDTKHNGILGFEEF 107 V DG ++ EE + + K K +F D +G + FEEF Sbjct: 10 DVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEF 58 Score = 32.3 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 20/41 (48%) Query: 167 IIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYL 207 + + F+E D DG + EE ++ V + ++ LQ + Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLI 41 >3JBH-C nrPDB Length = 156 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 53/154 (34%), Gaps = 12/154 (7%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 +E+E E F +G I+ + L + K +L + D + L Sbjct: 7 AEVEKAREHF--EIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNGGSDKRGEKKLTL 64 Query: 105 EEFARALSVFHPNAPID--DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDT 162 EEF S + + ++YD + G + E+ ++++ G L D Sbjct: 65 EEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSL----GERLTDI 120 Query: 163 VIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHP 196 E+ D DG + E + ++ P Sbjct: 121 ECEE----IMRVCDEDDDGFLKYEPFVKTIIAGP 150 >5B7X-A nrPDB Length = 156 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 46/132 (34%), Gaps = 13/132 (9%) Query: 64 DGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPID 121 DG I+ ++ + E + + F + E+F + Sbjct: 27 DGKIDVKQLGTLIRSLGCAPTEDEVNSYIKE-FAIEGE-TFQIEQFELIMEREQSKPDTR 84 Query: 122 D-KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 + K+ +F+++D + G I+ ++ + D + ++ ++K F + Sbjct: 85 EIKLRKAFEVFDQDKDGKIKASDLAHNLTTV--------GDKMTKEEVEKVFSILGITME 136 Query: 181 GKIDKEEWRSLV 192 ID + LV Sbjct: 137 SDIDLATFLKLV 148 Score = 29.6 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 23/91 (25%), Gaps = 29/91 (31%) Query: 122 DKIHFSFQLYDLKQQGFIE-----------------------------RQEVKQMVVATL 152 KI F YD G I+ E Q+ L Sbjct: 13 QKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGETFQIEQFEL 72 Query: 153 AESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 K E + K FE D DGKI Sbjct: 73 IMEREQSKPDTREIKLRKAFEVFDQDKDGKI 103 >6MI5-X nrPDB Length = 117 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 36/102 (35%), Gaps = 18/102 (17%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FD +G + +E A S +F D + G ++ +E+K V Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSA-------------AFDKLDPDKDGTLDAKELKGRVSE 55 Query: 151 --TLAESGMNLKDTVIED---IIDKTFEEADTKHDGKIDKEE 187 N ++ ++ F+ A+ +DG ID E Sbjct: 56 ADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDARE 97 Score = 32.7 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 31/91 (34%), Gaps = 25/91 (27%) Query: 54 FKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSV 113 F K+ DG ++ +E + ++ D ++G L +E+ A+ Sbjct: 33 FDKLDPD--KDGTLDAKELK----------GRVSEADLKKLDPDNDGTLDKKEYLAAVEA 80 Query: 114 FHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 F+ + G I+ +E+ Sbjct: 81 Q-------------FKAANPDNDGTIDAREL 98 >3MSE-B nrPDB Length = 180 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 52/144 (36%), Gaps = 9/144 (6%) Query: 52 ELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARAL 111 ELF K+ + +G ++ E + + + +R+ D G + + EF Sbjct: 43 ELFYKLDTN--HNGSLSHREI-YTVLASVGIKKWDINRILQALDINDRGNITYTEFMAG- 98 Query: 112 SVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMV-VATLAESGMNLKDTVIEDIIDK 170 + + +F D + G+I + ++ +V L + ++ + I Sbjct: 99 -CYRWKNIESTFLKAAFNKIDKDEDGYISKSDIVSLVHDKVLDNNDIDNFFLSVHSIKKG 157 Query: 171 TFEEADTKHDGKIDKEEWRSLVLR 194 E KI +E++ +L Sbjct: 158 IPREHIIN---KISFQEFKDYMLS 178 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 38/108 (35%), Gaps = 12/108 (11%) Query: 85 LFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 + + +F DT HNG L E L+ ++I + D+ +G I E Sbjct: 39 KYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWDINRILQAL---DINDRGNITYTEF 95 Query: 145 KQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 +G + + F + D DG I K + SLV Sbjct: 96 ---------MAGCYRWKNIESTFLKAAFNKIDKDEDGYISKSDIVSLV 134 Score = 34.6 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 33/100 (33%), Gaps = 10/100 (10%) Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 I+ F D G + +E+ ++ + G+ D I++ + D G I Sbjct: 41 INELFYKLDTNHNGSLSHREIYTVLASV----GIKKWD------INRILQALDINDRGNI 90 Query: 184 DKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQV 223 E+ + R ++ I ++ S + Sbjct: 91 TYTEFMAGCYRWKNIESTFLKAAFNKIDKDEDGYISKSDI 130 >1RTP-1 nrPDB Length = 109 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 34/96 (35%), Gaps = 8/96 (8%) Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 ++F + + + +A + F + D + GFIE E+ ++ + Sbjct: 22 DSFDHKKFFQMVGLKKKSAD---DVKKVFHILDKDKSGFIEEDELGSILKGF-----SSD 73 Query: 160 KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 + D DGKI EE+ +LV Sbjct: 74 ARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVAES 109 Score = 29.2 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 26/77 (33%), Gaps = 2/77 (2%) Query: 74 LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAP--IDDKIHFSFQLY 131 + KK + +VF + D +G + +E L F +A + Sbjct: 30 FQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAG 89 Query: 132 DLKQQGFIERQEVKQMV 148 D G I +E +V Sbjct: 90 DKDGDGKIGVEEFSTLV 106 >1N2D-A nrPDB Length = 148 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + +FQ++D + G + +++ M+ L + + + +D+ + + +G Sbjct: 83 EDFVKAFQVFDKESTGKVSVGDLRYMLTG--------LGEKLTDAEVDELLKGVEVDSNG 134 Query: 182 KIDKEEWRSLVLR 194 +ID +++ VLR Sbjct: 135 EIDYKKFIEDVLR 147 Score = 30.0 bits (66), Expect = 0.89, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 29/78 (37%), Gaps = 4/78 (5%) Query: 32 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 91 + + L T + +++F K S+ + G + L T+ + D + Sbjct: 70 NEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAE----VDELL 125 Query: 92 DLFDTKHNGILGFEEFAR 109 + NG + +++F Sbjct: 126 KGVEVDSNGEIDYKKFIE 143 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 7/90 (7%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F L+D K QG I + + + A G N + +++DII+ D + ++ Sbjct: 10 FTLFDKKGQGAIAKDSLGDYLRAI----GYNPTNQLVQDIINADSSLRDA---SSLTLDQ 62 Query: 188 WRSLVLRHPSLLKNMTLQYLKDITTTFPSF 217 L+ + L T +D F F Sbjct: 63 ITGLIEVNEKELDATTKAKTEDFVKAFQVF 92 >2JOJ-A nrPDB Length = 77 Score = 40.4 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 32/74 (43%), Gaps = 8/74 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +I +F L+D + G I+ E+K + A L V + I + E D + +G Sbjct: 7 QEIKEAFDLFDTNKTGSIDYHELKVAMRA--------LGFDVKKPEILELMNEYDREGNG 58 Query: 182 KIDKEEWRSLVLRH 195 I +++ ++ Sbjct: 59 YIGFDDFLDIMTEK 72 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 FDLFDT G + + E A+ + + I YD + G+I + ++ Sbjct: 13 FDLFDTNKTGSIDYHELKVAMRALGFDVKKPE-ILELMNEYDREGNGYIGFDDFLDIMTE 71 Query: 151 TLA 153 + Sbjct: 72 KIK 74 Score = 34.6 bits (78), Expect = 0.034, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 35/78 (44%), Gaps = 8/78 (10%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 EI+ ++LF G I+ E ++A+ + K+ + + + +D + NG Sbjct: 6 KQEIKEAFDLFDT-----NKTGSIDYHELKVAMRALGFDVKKPEILELMNE-YDREGNGY 59 Query: 102 LGFEEFARALSVFHPNAP 119 +GF++F ++ N Sbjct: 60 IGFDDFLDIMTEKIKNRD 77 >5VE9-A nrPDB Length = 91 Score = 40.4 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 35/95 (36%), Gaps = 14/95 (14%) Query: 19 FDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFK 78 FD D++++ R S + + K DG I ++EF + Sbjct: 9 FDFDVWRKK--------YMRWMNHKKSRVMDFFRRIDKD-----QDGKITRQEFIDGILA 55 Query: 79 TN-KKESLFADRVFDLFDTKHNGILGFEEFARALS 112 + L V D+FD +G + + EF AL Sbjct: 56 SKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALH 90 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 10/63 (15%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI-IDKTFEEADTKHDGKIDKE 186 F+ D Q G I RQE ++A T +E + F D DG ID Sbjct: 33 FRRIDKDQDGKITRQEFIDGILA------SKFPTTKLEMTAVADIF---DRDGDGYIDYY 83 Query: 187 EWR 189 E+ Sbjct: 84 EFV 86 Score = 35.4 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDI 210 + + F D DGKI ++E+ +L + + + DI Sbjct: 26 KSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADI 71 >2K7B-A nrPDB Length = 76 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 8/71 (11%), Positives = 32/71 (45%), Gaps = 8/71 (11%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +++ +F+ +D + G+I +++ + G + + ++ ++ + G Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTM----GYMPTEMELIELS----QQINMNLGG 61 Query: 182 KIDKEEWRSLV 192 +D +++ L+ Sbjct: 62 HVDFDDFVELM 72 Score = 28.1 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 23/70 (32%), Gaps = 8/70 (11%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLAL--FKTNKKESLFADRVFDLFDTKHNGI 101 + E+ + F K DG IN + + E + + + G Sbjct: 9 IEELREAFREFDKD-----KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGH 62 Query: 102 LGFEEFARAL 111 + F++F + Sbjct: 63 VDFDDFVELM 72 >4NQG-A nrPDB Length = 197 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 85 LFADRVFDLFDTKHNGILGFEEFARALS---VFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 L+ D +FD+ D NG + +E+ + + + +F DL G ++ Sbjct: 114 LWGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEA----TFAHCDLDGDGKLDV 169 Query: 142 QEVKQ 146 E+ + Sbjct: 170 DEMTR 174 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 38/128 (29%), Gaps = 18/128 (14%) Query: 78 KTNKKESLFADRVFDLFDTKHNGILGFEEFA--------RALSVFHPNAPIDDKIHFSF- 128 N K +F+ D NG + E + L K F Sbjct: 14 FDNPKWIARHKHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFF 73 Query: 129 ----QLYDLKQQ--GFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 YD +I + K++ L N + T+I D F+ D +G Sbjct: 74 GGAGLEYDKDTTWPEYI--EGWKRLAKTELERHSKN-RVTLIRLWGDALFDIIDKDGNGS 130 Query: 183 IDKEEWRS 190 + +EW Sbjct: 131 VSLDEWIQ 138 Score = 34.6 bits (78), Expect = 0.034, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 19/62 (30%), Gaps = 12/62 (19%) Query: 128 FQLYDLKQQGFIERQEVKQMVVA--TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDK 185 F + D G + E Q G + TF D DGK+D Sbjct: 120 FDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQC----------EATFAHCDLDGDGKLDV 169 Query: 186 EE 187 +E Sbjct: 170 DE 171 >1TIZ-A nrPDB Length = 67 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ +D + G + E +++ +A ++ I K FEE D +G+++ +E Sbjct: 7 FEKFDKNKDGKLSLDEFREVALAF--------SPYFTQEDIVKFFEEIDVDGNGELNADE 58 Query: 188 WRSLVLR 194 + S + + Sbjct: 59 FTSCIEK 65 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 A RVF+ FD +G L +EF F P +D + F F+ D+ G + E Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKF-FEEIDVDGNGELNADE 58 Score = 31.2 bits (69), Expect = 0.41, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 15/26 (57%) Query: 168 IDKTFEEADTKHDGKIDKEEWRSLVL 193 + FE+ D DGK+ +E+R + L Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVAL 28 >1NYA-A nrPDB Length = 176 Score = 40.0 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 41/112 (36%), Gaps = 14/112 (12%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPID------DKIHFSFQ-LYD-------LKQQ 136 FD +D NG L +F + D + +F L+D + Sbjct: 13 FDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKEAGVGSD 72 Query: 137 GFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 G + ++ ++ + E G + V+ ++ D DG+I+ +E+ Sbjct: 73 GSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEF 124 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 34/105 (32%), Gaps = 12/105 (11%) Query: 54 FKKISSAVIDDGLINKEEFQLA---LFKTNKKES------LFADRVFDLFDTKHNGILGF 104 + + V DG + +E+F L + S + + D +G + Sbjct: 62 YLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINA 121 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 +EFA L+ + +F D G + E+ V Sbjct: 122 DEFAAWLTAL---GMSKAEAAEAFNQVDTNGNGELSLDELLTAVR 163 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 30/78 (38%), Gaps = 7/78 (8%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIED-------IIDKTFE 173 D++ F +D G +ER + ++ G + ++ + D + Sbjct: 6 SDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAK 65 Query: 174 EADTKHDGKIDKEEWRSL 191 EA DG + +E++ + Sbjct: 66 EAGVGSDGSLTEEQFIRV 83 Score = 31.9 bits (71), Expect = 0.25, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 23/62 (37%), Gaps = 10/62 (16%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 D G I E A L GM+ + + F + DT +G++ +E + Sbjct: 112 DKNADGQINADE----FAAWLTALGMSKAEAA------EAFNQVDTNGNGELSLDELLTA 161 Query: 192 VL 193 V Sbjct: 162 VR 163 Score = 30.0 bits (66), Expect = 0.75, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 64 DGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFH 115 DG IN +EF L ++ A+ F+ DT NG L +E A+ FH Sbjct: 116 DGQINADEFAAWLTALGMSKAEAAEA-FNQVDTNGNGELSLDELLTAVRDFH 166 >1DFK-Y nrPDB Length = 139 Score = 40.0 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 60/153 (39%), Gaps = 18/153 (11%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLA--LFKTNKKESLFADRVFDLFDTKHNG 100 +I+ + E F I V DG ++KE+ + + + + G Sbjct: 2 PQKQIQEMKEAFSMID--VDRDGFVSKEDIKAISEQLGRAPDDKELTAML-----KEAPG 54 Query: 101 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK 160 L F F S ++ I +F ++D ++ + + +K ++ N+ Sbjct: 55 PLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLL--------ENMG 106 Query: 161 DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 D +D + TF+EA + GK D ++ +++ Sbjct: 107 DNFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIK 138 Score = 32.3 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 38/99 (38%), Gaps = 14/99 (14%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDK--------TFE 173 ++ +F + D+ + GF+ +++ + A + G D + ++ + F Sbjct: 7 QEMKEAFSMIDVDRDGFVSKED----IKAISEQLGRAPDDKELTAMLKEAPGPLNFTMFL 62 Query: 174 EADTKHDGKIDKEEWRS--LVLRHPSLLKNMTLQYLKDI 210 + D EE + K + ++Y+KD+ Sbjct: 63 SIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDL 101 >5CPV-A nrPDB Length = 109 Score = 40.0 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 D + +F + D + GFIE E+K ++ + + + D+ Sbjct: 39 KSADDVKKAFAIIDQDKSGFIEEDELK-----LFLQNFKADARALTDGETKTFLKAGDSD 93 Query: 179 HDGKIDKEEWRSLVL 193 DGKI +E+ +LV Sbjct: 94 GDGKIGVDEFTALVK 108 Score = 26.9 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 26/79 (32%), Gaps = 2/79 (2%) Query: 74 LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAP--IDDKIHFSFQLY 131 A K + + F + D +G + +E L F +A D + + Sbjct: 31 FAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAG 90 Query: 132 DLKQQGFIERQEVKQMVVA 150 D G I E +V A Sbjct: 91 DSDGDGKIGVDEFTALVKA 109 >2MA2-A nrPDB Length = 81 Score = 40.0 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 23/61 (37%), Gaps = 8/61 (13%) Query: 84 SLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 + VF FD +G + EEF F + +F D Q G I R+E Sbjct: 12 EKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLS--------AFGDLDQNQDGCISREE 63 Query: 144 V 144 + Sbjct: 64 M 64 Score = 35.4 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 15/80 (18%) Query: 120 IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 I+ + F+ +D+ G I ++E Q++ F + D Sbjct: 11 IEKMVESVFRNFDVDGDGHISQEE-FQIIRGNFPYL--------------SAFGDLDQNQ 55 Query: 180 DGKIDKEEWRSLVLRHPSLL 199 DG I +EE S LR S+L Sbjct: 56 DGCISREEMVSYFLRSSSVL 75 Score = 34.3 bits (77), Expect = 0.041, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 15/28 (53%) Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWR 189 IE +++ F D DG I +EE++ Sbjct: 9 EHIEKMVESVFRNFDVDGDGHISQEEFQ 36 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 15/78 (19%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILG 103 +E+++ F DG I++EEFQ+ + S F D D +G + Sbjct: 12 EKMVESVFRNFDVDG-----DGHISQEEFQI-IRGNFPYLSAFGD-----LDQNQDGCIS 60 Query: 104 FEE----FARALSVFHPN 117 EE F R+ SV Sbjct: 61 REEMVSYFLRSSSVLGGR 78 >2LVV-A nrPDB Length = 226 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 52/151 (34%), Gaps = 24/151 (15%) Query: 49 ALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHN--------- 99 L++ F + + G + + K ++ + D V FD + Sbjct: 55 ELFKQFDTNGTGKL--GFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVG 112 Query: 100 --GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 ++ F EF L + ++ F D +E QE K+ + L E G+ Sbjct: 113 EEDLVEFLEFRLMLCYIYDIF----ELTVMFDTMDKDGSLLLELQEFKEAL-PKLKEWGV 167 Query: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 ++ D F E DT G + +E+ Sbjct: 168 DITDATT------VFNEIDTNGSGVVTFDEF 192 Score = 32.3 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTN--KKESLFADRVFDLFDTKHN 99 + + E+ +++ K S L+ +EF+ AL K + A VF+ DT + Sbjct: 130 YDIFELTVMFDTMDKDGSL-----LLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGS 184 Query: 100 GILGFEEF 107 G++ F+EF Sbjct: 185 GVVTFDEF 192 Score = 30.8 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 41/117 (35%), Gaps = 23/117 (19%) Query: 90 VFDLFDTKHNGILGFEEFARA----LSVFHPNAPIDDKIHFSF--------QLYDLKQQG 137 +F FDT G LGF E L + + D + +F ++ + ++ Sbjct: 56 LFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEED 115 Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 +E E + M+ + + F+ D ++ +E++ + + Sbjct: 116 LVEFLEFRLMLCYIYDIFELTV-----------MFDTMDKDGSLLLELQEFKEALPK 161 >5I2L-A nrPDB Length = 120 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 32/91 (35%), Gaps = 17/91 (18%) Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 N F+EF+R + F+ YD + GFI+ E+K M+ Sbjct: 17 NPYTEFKEFSR---------KQIKDMEKMFKQYDAGRDGFIDLMELKLMM--------EK 59 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 L + +E D D K+ E+ Sbjct: 60 LGAPQTHLGLKNMIKEVDEDFDSKLSFREFL 90 Score = 26.6 bits (57), Expect = 8.6, Method: Composition-based stats. Identities = 6/63 (9%), Positives = 19/63 (30%), Gaps = 1/63 (1%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 +++F +D +G + E + + + + D + +E Sbjct: 33 MEKMFKQYDAGRDGFIDLME-LKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLL 91 Query: 147 MVV 149 + Sbjct: 92 IFR 94 >2I18-A nrPDB Length = 64 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 29/70 (41%), Gaps = 12/70 (17%) Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 + ++L D+ G + ++E V + + G+ + + + +AD DG I Sbjct: 7 LKVLYKLMDVDGDGKLTKEE----VTSFFKKHGI--------EKVAEQVMKADANGDGYI 54 Query: 184 DKEEWRSLVL 193 EE+ L Sbjct: 55 TLEEFLEFSL 64 Score = 28.1 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 25/63 (39%), Gaps = 8/63 (12%) Query: 47 IEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEE 106 ++ LY+L DG + KEE + F A++V D +G + EE Sbjct: 7 LKVLYKLMDVDG-----DGKLTKEE--VTSFFKKHGIEKVAEQVMKA-DANGDGYITLEE 58 Query: 107 FAR 109 F Sbjct: 59 FLE 61 >2SAS-A nrPDB Length = 185 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 42/132 (31%), Gaps = 16/132 (12%) Query: 78 KTNKKESLFADRVFDLF-DTKHNGILGFEEFARALSV--------------FHPNAPIDD 122 N + FD F D H+G + +F ++ A ++D Sbjct: 1 GLNDFQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLED 60 Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMV-VATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + D+ + + +E M + ++ I F+ D DG Sbjct: 61 EWRDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDG 120 Query: 182 KIDKEEWRSLVL 193 +D EE+++ Sbjct: 121 IVDLEEFQNYCK 132 >1TTX-A nrPDB Length = 109 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 +++ F+ D Q G+++ +E+K + + + E AD DG Sbjct: 42 NQVKDVFRFIDNDQSGYLDEEELKFFLQKF-----ESGARELTESETKSLMAAADNDGDG 96 Query: 182 KIDKEEWRSLV 192 KI EE++ +V Sbjct: 97 KIGAEEFQEMV 107 Score = 27.3 bits (59), Expect = 4.9, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 28/77 (36%), Gaps = 9/77 (11%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADR----VFDLFD 95 + S ++++ ++ G +++EE + L K + + D Sbjct: 37 SKMSANQVKDVFRFIDND-----QSGYLDEEELKFFLQKFESGARELTESETKSLMAAAD 91 Query: 96 TKHNGILGFEEFARALS 112 +G +G EEF + Sbjct: 92 NDGDGKIGAEEFQEMVH 108 >1SL8-A nrPDB Length = 191 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Query: 85 LFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV 144 L+ D +FD+ D NG + +E+ +A + + +F++ D+ + G ++ E+ Sbjct: 109 LWGDALFDIIDKDQNGAISLDEW-KAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 Query: 145 KQ 146 + Sbjct: 168 TR 169 Score = 33.5 bits (75), Expect = 0.072, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 38/131 (29%), Gaps = 16/131 (12%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF--------ARALSVFHPNAPIDDKI 124 +L N K +F+ D HNG + +E L A Sbjct: 4 KLTPDFDNPKWIGRHKHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDA 63 Query: 125 HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDII------DKTFEEADTK 178 +F + + E + + + LK I D F+ D Sbjct: 64 VEAF--FGGAGMKYGVETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKD 121 Query: 179 HDGKIDKEEWR 189 +G I +EW+ Sbjct: 122 QNGAISLDEWK 132 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 22/60 (36%), Gaps = 8/60 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F + D Q G I E A +G+ E+ TF D G++D +E Sbjct: 115 FDIIDKDQNGAISLDE----WKAYTKSAGIIQSSEDCEE----TFRVCDIDESGQLDVDE 166 >1S6J-A nrPDB Length = 87 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 24/66 (36%), Gaps = 8/66 (12%) Query: 124 IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 + F++ D G I E+K + + ++E I + AD G I Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLK--------RVGSELMESEIKDLMDAADIDKSGTI 76 Query: 184 DKEEWR 189 D E+ Sbjct: 77 DYGEFI 82 Score = 34.3 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 6/86 (6%) Query: 27 SGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKES 84 SG + D + + S EI L ELFK I + G I +E + L + ES Sbjct: 3 SGHIDDDDKHMAE-RLSEEEIGGLKELFKMID--TDNSGTITFDELKDGLKRVGSELMES 59 Query: 85 LFADRVFDLFDTKHNGILGFEEFARA 110 D + D D +G + + EF A Sbjct: 60 EIKDLM-DAADIDKSGTIDYGEFIAA 84 Score = 32.3 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Query: 64 DGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDK 123 G I+ ++ +A + ++ + +F + DT ++G + F+E L + ++ + Sbjct: 3 SGHIDDDDKHMAERLSEEEIGGLKE-LFKMIDTDNSGTITFDELKDGLKRV-GSELMESE 60 Query: 124 IHFSFQLYDLKQQGFIERQE 143 I D+ + G I+ E Sbjct: 61 IKDLMDAADIDKSGTIDYGE 80 Score = 27.3 bits (59), Expect = 6.1, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 26/57 (45%), Gaps = 3/57 (5%) Query: 156 GMNLKDTVIEDII---DKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKD 209 ++ + + E+ I + F+ DT + G I +E + + R S L ++ L D Sbjct: 10 DKHMAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMD 66 >1F4Q-A nrPDB Length = 165 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 49/138 (35%), Gaps = 23/138 (16%) Query: 63 DDGLINKEEFQ--LALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSVFHP 116 DG ++ EE Q L N S F+ + D H G +GF F + + Sbjct: 12 QDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNA 71 Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 +F D G +E E++Q + G L + I+ + Sbjct: 72 -------WKENFMTVDQDGSGTVEHHELRQAI----GLMGYRLSPQTLTTIVKRY----- 115 Query: 177 TKHDGKIDKEEWRSLVLR 194 +G+I +++ + ++ Sbjct: 116 -SKNGRIFFDDYVACCVK 132 >1BU3-A nrPDB Length = 109 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 5/77 (6%) Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 A D I +F + D + GFIE E+K + A + + + + D Sbjct: 37 TAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGAR-----ALTDAETKAFLKAGD 91 Query: 177 TKHDGKIDKEEWRSLVL 193 + DG I +EW +LV Sbjct: 92 SDGDGAIGVDEWAALVK 108 Score = 28.1 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 22/58 (37%), Gaps = 4/58 (6%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSV 113 G I ++E +L L + D F D+ +G +G +E+A + Sbjct: 52 DQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIGVDEWAALVKA 109 >1CB1-A nrPDB Length = 78 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Query: 139 IERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + ++E+KQ++ A + +D F+E D DG++ EE++ LV + Sbjct: 26 LSKEELKQLIQAEFPSLLKGPRT------LDDLFQELDKNGDGEVSFEEFQVLVKK 75 Score = 30.4 bits (67), Expect = 0.71, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 3/70 (4%) Query: 49 ALYELFKKISSAVIDDGLINKEEFQLALFKTNK---KESLFADRVFDLFDTKHNGILGFE 105 L +F+K ++ D ++KEE + + K D +F D +G + FE Sbjct: 8 ELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFE 67 Query: 106 EFARALSVFH 115 EF + Sbjct: 68 EFQVLVKKIS 77 >2EC6-B nrPDB Length = 133 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 52/147 (35%), Gaps = 14/147 (9%) Query: 47 IEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEE 106 ++ + E F I IN + + + + + + G L F Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAML-----KEAPGPLNFTM 55 Query: 107 FARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIED 166 F S ++ I +F ++D + + +K ++ N+ D +D Sbjct: 56 FLSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLL--------ENMGDNFNKD 107 Query: 167 IIDKTFEEADTKHDGKIDKEEWRSLVL 193 + TF+EA + GK D + +++ Sbjct: 108 EMRMTFKEAPVEG-GKFDYVRFVAMIK 133 >1RK9-A nrPDB Length = 110 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 35/99 (35%), Gaps = 8/99 (8%) Query: 97 KHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESG 156 ++F + + + +A + F + D + GFIE E+ ++ ++ Sbjct: 20 SATDSFDHKKFFQMVGLKKKSAD---DVKKVFHMLDKDKSGFIEEDELGFILKGFSPDAR 76 Query: 157 MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 + D DGKI +E+ +LV Sbjct: 77 -----DLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES 110 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 26/77 (33%), Gaps = 2/77 (2%) Query: 74 LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAP--IDDKIHFSFQLY 131 + KK + +VF + D +G + +E L F P+A + Sbjct: 31 FQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAG 90 Query: 132 DLKQQGFIERQEVKQMV 148 D G I E +V Sbjct: 91 DKDGDGKIGVDEFSTLV 107 Score = 27.3 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 28/74 (37%), Gaps = 9/74 (12%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFA----DRVFDLFDTKH 98 S +++ ++ + K G I ++E L + + + D Sbjct: 40 SADDVKKVFHMLDKD-----KSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDG 94 Query: 99 NGILGFEEFARALS 112 +G +G +EF+ ++ Sbjct: 95 DGKIGVDEFSTLVA 108 >2WCE-A nrPDB Length = 95 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 3/55 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + + E+KQ++ LA + N+KD +ID+ F+ D D ++D +E+ S+V Sbjct: 30 TLSKGELKQLLTKELANTIKNIKDKA---VIDEIFQGLDANQDEQVDFQEFISMV 81 Score = 33.5 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 54 FKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSV 113 F +S + L+ KE LA N K+ D +F D + + F+EF +++ Sbjct: 28 FDTLSKGELKQ-LLTKE---LANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVAI 83 Query: 114 FHPNA 118 A Sbjct: 84 ALKAA 88 >1BOD-A nrPDB Length = 74 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 10/78 (12%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI--IDKTFEEAD 176 +++ F+ YD + G Q+ L ++++ + +D+ FEE D Sbjct: 2 KSPEELKGIFEKYDKEGDG--------QLSKEELKLLLQTEFPSLLKGMSTLDELFEELD 53 Query: 177 TKHDGKIDKEEWRSLVLR 194 DG++ EE++ LV + Sbjct: 54 KNGDGEVSFEEFQVLVKK 71 Score = 26.9 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%), Gaps = 2/73 (2%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGIL 102 S E++ ++E + K + + +L D +F+ D +G + Sbjct: 3 SPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTL--DELFEELDKNGDGEV 60 Query: 103 GFEEFARALSVFH 115 FEEF + Sbjct: 61 SFEEFQVLVKKIS 73 >1Q80-A nrPDB Length = 174 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALS-VFHPNA 118 +D I+++E+ + F + A FD DT ++G+L EEF A S F + Sbjct: 104 DTNEDNNISRDEYGIF-FGMLGLDKTMAPASFDAIDTNNDGLLSLEEFVIAGSDFFMNDG 162 Query: 119 PIDDKIHF 126 +K+ + Sbjct: 163 DSTNKVFW 170 Score = 35.0 bits (79), Expect = 0.023, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 48/146 (32%), Gaps = 26/146 (17%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDT------------KHNGILGFEEF 107 DG I + +F+ + K+ + A+ L D+ + F Sbjct: 16 DFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVAGGKGIDETTF 75 Query: 108 ARALS--VFHPNAP--IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTV 163 ++ V +P A ++ + F+ D + I R E + L + Sbjct: 76 INSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDE-YGIFFGMLGLDKTMAPAS- 133 Query: 164 IEDIIDKTFEEADTKHDGKIDKEEWR 189 F+ DT +DG + EE+ Sbjct: 134 --------FDAIDTNNDGLLSLEEFV 151 Score = 26.9 bits (58), Expect = 7.7, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 14/37 (37%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 K+ F D + G I R + + M ES M Sbjct: 6 QKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMK 42 >6AGH-A nrPDB Length = 339 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 49/109 (44%), Gaps = 7/109 (6%) Query: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFADRVFDLFDTKHNG 100 F+ +E + +Y +K + + I+ +EF+ F T+ ++ A ++F L + Sbjct: 231 FTNTENKDIY--WKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQMFSL----AHR 284 Query: 101 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + EF RA+ V ++ + F+++DL + +E ++ Sbjct: 285 PVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLK 333 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 19/129 (14%), Positives = 47/129 (36%), Gaps = 15/129 (11%) Query: 95 DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 D G++ + E+ L++ H +F++ D IE++E ++ + Sbjct: 92 DLGDKGLISYTEYLFLLTILT---KPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQ 148 Query: 155 SGMNLKDTVIEDIIDKTFEEADTK-----------HDGKIDKEEWRSLVLRHPSLLKNMT 203 + T + +E + K+ +E+R + + ++ M Sbjct: 149 DDLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEME 208 Query: 204 -LQYLKDIT 211 LQ+ K ++ Sbjct: 209 FLQFSKGLS 217 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 21/54 (38%), Gaps = 2/54 (3%) Query: 67 INKEEFQLALFKTNKKE--SLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 + EF+ A+ +E + D VF +FD + L EEF L Sbjct: 286 VRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRMHRG 339 >2FCE-A nrPDB Length = 70 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 35/73 (47%), Gaps = 8/73 (10%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + +FQ++D + G + +++ M+ L + + + +D+ + + +G Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTG--------LGEKLTDAEVDELLKGVEVDSNG 56 Query: 182 KIDKEEWRSLVLR 194 +ID +++ VLR Sbjct: 57 EIDYKKFIEDVLR 69 >1JUO-A nrPDB Length = 198 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 49/138 (35%), Gaps = 23/138 (16%) Query: 63 DDGLINKEEFQ--LALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSVFHP 116 DG I+ +E Q L F L D +G +GF EF +V + Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG 104 Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 F +D + G ++ QE+++ + G L ++ + Sbjct: 105 -------WRQHFISFDTDRSGTVDPQELQKALTTM----GFRLSP----QAVNSIAKRYS 149 Query: 177 TKHDGKIDKEEWRSLVLR 194 T GKI +++ + ++ Sbjct: 150 TN--GKITFDDYIACCVK 165 Score = 28.1 bits (61), Expect = 2.8, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 34/106 (32%), Gaps = 19/106 (17%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F FDT +G + +E +AL+ ++ + Y G I + V Sbjct: 109 FISFDTDRSGTVDPQELQKALTT-MGFRLSPQAVNSIAKRY--STNGKITFDDYIACCVK 165 Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDK--EEWRSLVLR 194 A + F DT G ++ +++ V+ Sbjct: 166 LRALTDS--------------FRRRDTAQQGVVNFPYDDFIQCVMS 197 >1G33-A nrPDB Length = 73 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 27/77 (35%), Gaps = 5/77 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 D + F + D + GFIE E+ ++ + + D Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGF-----SSDARDLSAKETKTLMAAGDKD 56 Query: 179 HDGKIDKEEWRSLVLRH 195 DGKI EE+ +LV Sbjct: 57 GDGKIGVEEFSTLVAES 73 Score = 27.3 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAP--IDDKIHFSFQLYDLKQQGFIERQEVKQ 146 +VF + D +G + +E L F +A + D G I +E Sbjct: 9 KVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFST 68 Query: 147 MV 148 +V Sbjct: 69 LV 70 >1ZFS-A nrPDB Length = 93 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + ++E+K ++ L+ KD D +DK +E D DG++D +E+ Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDA---DAVDKIMKELDENGDGEVDFQEFV 75 Score = 33.5 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 34/78 (43%), Gaps = 6/78 (7%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQ------LALFKTNKKESLFADRVFDLFDTK 97 + +E L +F S D ++K+E + L+ F +K++ D++ D Sbjct: 5 ETAMETLINVFHAHSGKEGDKYKLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDEN 64 Query: 98 HNGILGFEEFARALSVFH 115 +G + F+EF ++ Sbjct: 65 GDGEVDFQEFVVLVAALT 82 >2NLN-A nrPDB Length = 108 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ D Q G+++ E+K + L ++ + ++D AD DGKI +E Sbjct: 47 FRFIDNDQSGYLDGDELKYFLQ-KFQSDARELTESETKSLMDA----ADNDGDGKIGADE 101 Query: 188 WRSLV 192 ++ +V Sbjct: 102 FQEMV 106 Score = 28.9 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 28/77 (36%), Gaps = 9/77 (11%) Query: 40 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADR----VFDLFD 95 + S S+++ ++ G ++ +E + L K + + D D Sbjct: 36 SKMSASQVKDIFRFIDND-----QSGYLDGDELKYFLQKFQSDARELTESETKSLMDAAD 90 Query: 96 TKHNGILGFEEFARALS 112 +G +G +EF + Sbjct: 91 NDGDGKIGADEFQEMVH 107 Score = 28.9 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 22/61 (36%), Gaps = 2/61 (3%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAP--IDDKIHFSFQLYDLKQQGFIERQEVKQM 147 +F D +G L +E L F +A + + D G I E ++M Sbjct: 46 IFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEM 105 Query: 148 V 148 V Sbjct: 106 V 106 >5H53-B nrPDB Length = 146 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILG 103 ++I+ E F I DG+I+KE+ + F + ++ + + D + +G + Sbjct: 1 QTQIQEFKEAFTVIDQN--RDGIIDKEDLR-DTFAAMGRLNVKNEEL-DAMMKEASGPIN 56 Query: 104 FEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F F A +D I +F++ D + +G I++Q ++++++ Sbjct: 57 FTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLIT 103 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 29/70 (41%), Gaps = 11/70 (15%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + +F + D + G I++++++ A + N + +D +EA G Sbjct: 5 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKN-------EELDAMMKEA----SG 53 Query: 182 KIDKEEWRSL 191 I+ + ++ Sbjct: 54 PINFTVFLTM 63 >5VT9-A nrPDB Length = 152 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 56/149 (37%), Gaps = 17/149 (11%) Query: 46 EIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFE 105 E + +Y F +S G ++ + + L + +AD+ F+ K L + Sbjct: 18 EADEMYARFNARASG----GKVSTGD-AMILARQLGLAPSYADK--QAFEEKSGDNLDYA 70 Query: 106 EFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIE 165 F + + + + +F +D+ + G++ R+++ +++ G L Sbjct: 71 SFQKFVGTSTHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMT----YGEPLTTEEFN 126 Query: 166 DIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + F +ID ++ +L Sbjct: 127 ALAAEYFTS------DQIDYRQFCKAMLE 149 >2LUC-A nrPDB Length = 105 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 6/75 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF------QLALFKTNKKESLFADRVFDLFDT 96 + IE+L +F+K + + ++K EF +LA F N+K+ DR+ DT Sbjct: 10 TERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDT 69 Query: 97 KHNGILGFEEFARAL 111 +G L F EF + Sbjct: 70 NSDGQLDFSEFLNLI 84 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 7/74 (9%) Query: 122 DKIHFSFQLYDLKQQGF---IERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 + + FQ Y + G+ + + E + LA N KD ++D+ ++ DT Sbjct: 15 ESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPG---VLDRMMKKLDTN 70 Query: 179 HDGKIDKEEWRSLV 192 DG++D E+ +L+ Sbjct: 71 SDGQLDFSEFLNLI 84 >2PMY-A nrPDB Length = 91 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 28/78 (35%), Gaps = 12/78 (15%) Query: 116 PNAPIDD--KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFE 173 + ++ ++ F D + G +ER+E A E + D + F+ Sbjct: 19 ADGDGEELARLRSVFAACDANRSGRLEREE----FRALCTELRVRPAD------AEAVFQ 68 Query: 174 EADTKHDGKIDKEEWRSL 191 D DG I +E+ Sbjct: 69 RLDADRDGAITFQEFARG 86 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 E+ L +F + G + +EEF+ + + + A+ VF D +G + F Sbjct: 24 EELARLRSVFAACDAN--RSGRLEREEFRALCTELRVRPAD-AEAVFQRLDADRDGAITF 80 Query: 105 EEFARA 110 +EFAR Sbjct: 81 QEFARG 86 Score = 33.1 bits (74), Expect = 0.094, Method: Composition-based stats. Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 VF D +G L EEF RAL P D + FQ D + G I QE Sbjct: 32 VFAACDANRSGRLEREEF-RALCTELRVRPADAEA--VFQRLDADRDGAITFQE 82 >4OCI-A nrPDB Length = 146 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 22/148 (14%), Positives = 52/148 (35%), Gaps = 18/148 (12%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNGIL 102 +++ + LF DG + EF+ + + + S A + + Sbjct: 6 EDLKESFLLFDGDG-----DGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRG---M 57 Query: 103 GFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDT 162 +E F S + D+I + + D ++GFI E+++++ D Sbjct: 58 SYELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTI--------GDN 109 Query: 163 VIEDIIDKTFEEADTKHDGKIDKEEWRS 190 + + I F G + +++ + Sbjct: 110 MEQKEITDLFTFMGIDEQGVVKVDDFIN 137 Score = 30.4 bits (67), Expect = 0.68, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 15/37 (40%) Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 ++ + SF L+D G++ E + +V Sbjct: 5 NEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMET 41 >2W4G-C nrPDB Length = 145 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 18/153 (11%), Positives = 47/153 (30%), Gaps = 12/153 (7%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGI-LG 103 EI E F +++ + N + + + + N + Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKIT 60 Query: 104 FEEFARALSVFHPNAP--IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 FEEF L N + +++D + G + E++ ++ + + Sbjct: 61 FEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVE 120 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 ++ + +G I+ E + ++ Sbjct: 121 ELM---------KGQEDSNGCINYEAFVKHIMS 144 >4PAL-A nrPDB Length = 108 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%), Gaps = 5/72 (6%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 D + +F + D + GFIE E+K ++ + + + D DG Sbjct: 41 DDVKKAFYVIDQDKSGFIEEDELK-----LFLQNFSPSARALTDAETKAFLADGDKDGDG 95 Query: 182 KIDKEEWRSLVL 193 I +E+ +++ Sbjct: 96 MIGVDEFAAMIK 107 Score = 30.8 bits (68), Expect = 0.55, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 22/58 (37%), Gaps = 4/58 (6%) Query: 60 AVIDDGLINKEEFQLALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSV 113 G I ++E +L L + D F D +G++G +EFA + Sbjct: 51 DQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVDEFAAMIKA 108 >2L50-A nrPDB Length = 102 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 I + ++M+ E L DT DK + D HDG+I +E+ Sbjct: 31 KISKSSFREMLQ---KELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEY 78 Score = 27.3 bits (59), Expect = 4.9, Method: Composition-based stats. Identities = 7/21 (33%), Positives = 13/21 (61%) Query: 87 ADRVFDLFDTKHNGILGFEEF 107 AD++ D H+G + F+E+ Sbjct: 58 ADKLIQNLDANHDGRISFDEY 78 >3A8R-A nrPDB Length = 179 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 56/133 (42%), Gaps = 12/133 (9%) Query: 65 GLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKI 124 G+ +EF + +F + ++ +V + + F E D+++ Sbjct: 53 GMDGSDEFAVQMFDSLARKRGIVKQVL-----TKDELKDFYE------QLTDQG-FDNRL 100 Query: 125 HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKID 184 F + D G + +EVK+++ + + + ++ ++ EE D + G I+ Sbjct: 101 RTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKERADEYTALIMEELDPTNLGYIE 160 Query: 185 KEEWRSLVLRHPS 197 E+ +L+L+ PS Sbjct: 161 MEDLEALLLQSPS 173 >5MRA-A nrPDB Length = 167 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 49/138 (35%), Gaps = 23/138 (16%) Query: 63 DDGLINKEEFQ--LALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSVFHP 116 DG I+ +E Q L F L D +G +GF EF +V + Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG 73 Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 F +D + G ++ QE+++ + G L ++ + Sbjct: 74 -------WRQHFISFDTDRSGTVDPQELQKALTTM----GFRLSP----QAVNSIAKRYS 118 Query: 177 TKHDGKIDKEEWRSLVLR 194 T GKI +++ + ++ Sbjct: 119 TN--GKITFDDYIACCVK 134 Score = 27.7 bits (60), Expect = 4.0, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 34/106 (32%), Gaps = 19/106 (17%) Query: 91 FDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 F FDT +G + +E +AL+ ++ + Y G I + V Sbjct: 78 FISFDTDRSGTVDPQELQKALTT-MGFRLSPQAVNSIAKRY--STNGKITFDDYIACCVK 134 Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDK--EEWRSLVLR 194 A + F DT G ++ +++ V+ Sbjct: 135 LRALTDS--------------FRRRDTAQQGVVNFPYDDFIQCVMS 166 >1QLS-A nrPDB Length = 99 Score = 37.7 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF------QLALFKTNKKESLFADRVFDLFDT 96 + IE+L +F+K + ++ I+K EF +LA F N+K+ DR+ D Sbjct: 8 TERCIESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDL 67 Query: 97 KHNGILGFEEFARAL 111 +G L F+EF + Sbjct: 68 DSDGQLDFQEFLNLI 82 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Query: 135 QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 I + E + LA N KD ++D+ ++ D DG++D +E+ +L+ Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDPG---VLDRMMKKLDLDSDGQLDFQEFLNLI 82 >1UHK-A nrPDB Length = 191 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 D +FD+ D NG + +E+ +A + + +F++ D+ + G ++ E+ + Sbjct: 111 GDALFDIVDKDQNGAITLDEW-KAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 32.3 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 21/60 (35%), Gaps = 8/60 (13%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F + D Q G I E K A + ++TF D G++D +E Sbjct: 115 FDIVDKDQNGAITLDEWKAYTKAA--------GIIQSSEDCEETFRVCDIDESGQLDVDE 166 Score = 31.6 bits (70), Expect = 0.31, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 44/132 (33%), Gaps = 18/132 (13%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEF--------ARALSVFHPNAPIDDKI 124 +L N + +F+ D HNG + +E L A Sbjct: 4 KLTSDFDNPRWIGRHKHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDA 63 Query: 125 HFSF-----QLYDLKQQ--GFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADT 177 +F Y ++ +I + K++ L + N T+I D F+ D Sbjct: 64 VEAFFGGAGMKYGVETDWPAYI--EGWKKLATDELEKYAKNEP-TLIRIWGDALFDIVDK 120 Query: 178 KHDGKIDKEEWR 189 +G I +EW+ Sbjct: 121 DQNGAITLDEWK 132 >2M7M-A nrPDB Length = 66 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%), Gaps = 1/58 (1%) Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE 143 A+ +F D +G + +EE +S + + F+ D G I++ E Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN-EQLLQLIFKSIDADGNGEIDQNE 57 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 8/64 (12%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F+ D+ G + +EVK V A E ++ F+ D +G+ID+ E Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKN--------EQLLQLIFKSIDADGNGEIDQNE 57 Query: 188 WRSL 191 + Sbjct: 58 FAKF 61 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 20/41 (48%) Query: 167 IIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYL 207 + + F+E D DG + EE ++ V + ++ LQ + Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLI 41 Score = 28.9 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 53 LFKKISSAVIDDGLINKEEFQLALFKTNK-KESLFADRVFDLFDTKHNGILGFEEF 107 LFK+I V DG ++ EE + + K K +F D NG + EF Sbjct: 5 LFKEID--VNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEF 58 >3TS5-B nrPDB Length = 161 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 54/155 (34%), Gaps = 18/155 (11%) Query: 41 VFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKH 98 ++ + E F I DG I+ + + + + + + Sbjct: 16 RLPQKLMQEMKEAFTMIDQN--RDGFIDINDLKEMFSSLGRTPDDKELTAML-----KEA 68 Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMN 158 G L F F S ++ I +F ++D + + +K ++ N Sbjct: 69 PGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLL--------EN 120 Query: 159 LKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + D +D + TF+EA + GK D + +++ Sbjct: 121 MGDNFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIK 154 Score = 32.3 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 37/98 (37%), Gaps = 6/98 (6%) Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID----KTFEE 174 + ++ +F + D + GFI+ ++K+M + ++++ F Sbjct: 20 KLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNFTMFLS 79 Query: 175 ADTKHDGKIDKEEWRSLV--LRHPSLLKNMTLQYLKDI 210 + D EE + K + ++Y+KD+ Sbjct: 80 IFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDL 117 >1NSH-A nrPDB Length = 101 Score = 36.6 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 6/75 (8%) Query: 43 SVSEIEALYELFKKISSAVIDDGLINKEEF------QLALFKTNKKESLFADRVFDLFDT 96 + IE+L +F+K + ++K EF +LA F N+K+ DR+ D Sbjct: 6 TERCIESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDL 65 Query: 97 KHNGILGFEEFARAL 111 +G L F+EF + Sbjct: 66 NSDGQLDFQEFLNLI 80 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 122 DKIHFSFQLYDLKQQG---FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTK 178 + + FQ Y + G + + E + LA N KD ++D+ ++ D Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPG---VLDRMMKKLDLN 66 Query: 179 HDGKIDKEEWRSLV 192 DG++D +E+ +L+ Sbjct: 67 SDGQLDFQEFLNLI 80 >3BOW-B nrPDB Length = 184 Score = 35.8 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 38/127 (29%), Gaps = 30/127 (23%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV----- 144 + + D+ G LGFEEF + K ++ +D + G I E+ Sbjct: 63 MVAVMDSDTTGKLGFEEFKYLWNNI-------KKWQGIYKRFDTDRSGTIGSNELPGAFE 115 Query: 145 ---KQMVVATLAESGMNLKDTVIEDIID-------------KTFEEADTKHDGKI--DKE 186 + + D D + F D G+I + + Sbjct: 116 AAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQ 175 Query: 187 EWRSLVL 193 EW L + Sbjct: 176 EWLQLTM 182 >2L0P-A nrPDB Length = 94 Score = 35.8 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + ++E+K+++ L+ KD D +DK +E D DG++D +E+ Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDV---DAVDKVMKELDENGDGEVDFQEYV 76 Score = 31.9 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 6/78 (7%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQ------LALFKTNKKESLFADRVFDLFDTK 97 + +E L +F S D ++K+E + L+ F +K+ D+V D Sbjct: 6 ETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDEN 65 Query: 98 HNGILGFEEFARALSVFH 115 +G + F+E+ ++ Sbjct: 66 GDGEVDFQEYVVLVAALT 83 >1GJY-A nrPDB Length = 167 Score = 35.4 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 48/138 (34%), Gaps = 23/138 (16%) Query: 63 DDGLINKEEFQ--LALFKTNKKESLFADRVFDLF----DTKHNGILGFEEFARALSVFHP 116 DG I+ +E Q L F L D +G +GF EF +V + Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNG 73 Query: 117 NAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEAD 176 F +D + G ++ QE+++ + G L + I + Sbjct: 74 -------WRQHFISFDSDRSGTVDPQELQKALTTM----GFRLNPQTVNSIAKRY----- 117 Query: 177 TKHDGKIDKEEWRSLVLR 194 GKI +++ + ++ Sbjct: 118 -STSGKITFDDYIACCVK 134 >2MBX-A nrPDB Length = 109 Score = 35.4 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 10/98 (10%) Query: 97 KHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESG 156 K G + F + + A I F++ D + F+E E+K L Sbjct: 20 KAEGSFDHKAFFTKVGL---AAKSPADIKKVFEIIDQDKSDFVEEDELK------LFLQN 70 Query: 157 MNLKDTVIEDIIDKTFEEA-DTKHDGKIDKEEWRSLVL 193 + + D K F +A D+ DGKI +E+ +++ Sbjct: 71 FSAGARALSDAETKVFLKAGDSDGDGKIGVDEFGAMIK 108 Score = 29.2 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 23/64 (35%), Gaps = 2/64 (3%) Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHP--NAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 +VF++ D + + +E L F A D + + D G I E Sbjct: 46 KVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGDGKIGVDEFGA 105 Query: 147 MVVA 150 M+ A Sbjct: 106 MIKA 109 >4NSC-A nrPDB Length = 401 Score = 35.4 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 32/98 (32%), Gaps = 4/98 (4%) Query: 25 KQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFK--TNKK 82 KQ LG + + + F +I E F S G F +F Sbjct: 86 KQPEHLGLDQYIIK--RFDGKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLST 143 Query: 83 ESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 + F +FD +G + EEF + S+ + Sbjct: 144 PQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSM 181 Score = 34.6 bits (78), Expect = 0.037, Method: Composition-based stats. Identities = 10/60 (16%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 G++ F ++ +V +F+++DL G ++ +E +Q+ +++ M + Sbjct: 127 GLISFSDYIFLTTVLS---TPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGM 183 Score = 32.3 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 21/42 (50%), Gaps = 4/42 (9%) Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMT 203 + + + F+ D DG++D EE+ + S++++ T Sbjct: 142 STPQRNFEIAFKMFDLNGDGEVDMEEFEQV----QSIIRSQT 179 Score = 30.8 bits (68), Expect = 0.53, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 13/31 (41%) Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 D VF LFD NG L +EF + Sbjct: 339 DVVFALFDCDGNGELSNKEFVSIMKQRLMRG 369 Score = 30.4 bits (67), Expect = 0.67, Method: Composition-based stats. Identities = 22/134 (16%), Positives = 48/134 (35%), Gaps = 16/134 (11%) Query: 64 DGLINKEEFQ---LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI 120 DG I + +F LA K+ R + G L F+E + + Sbjct: 244 DGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKG-LTFQEVENFFTFLKNINDV 302 Query: 121 DDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD 180 D + F Y + +++ ++Q+ + + + D F D + Sbjct: 303 DTALSF----YHMAG-ASLDKVTMQQVARTVAKV-------ELSDHVCDVVFALFDCDGN 350 Query: 181 GKIDKEEWRSLVLR 194 G++ +E+ S++ + Sbjct: 351 GELSNKEFVSIMKQ 364 Score = 29.2 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 13/35 (37%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDT 162 F L+D G + +E ++ L KD Sbjct: 342 FALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDM 376 >1KQV-A nrPDB Length = 79 Score = 35.0 bits (79), Expect = 0.029, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 169 DKTFEEADTKHDGKIDKEEWRSLVLR 194 D+ FEE D DG++ EE++ LV + Sbjct: 51 DELFEELDKNGDGEVSFEEFQVLVKK 76 Score = 27.3 bits (59), Expect = 6.0, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 13/28 (46%) Query: 88 DRVFDLFDTKHNGILGFEEFARALSVFH 115 D +F+ D +G + FEEF + Sbjct: 51 DELFEELDKNGDGEVSFEEFQVLVKKIS 78 >1KFU-L nrPDB Length = 699 Score = 34.6 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 42/118 (35%), Gaps = 28/118 (23%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + D+ D+ +G LG +EF + K ++ D+ + G + E+++ + Sbjct: 579 MVDMLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALE 631 Query: 150 ATLAESGMNLKDTVIEDIID---------------------KTFEEADTKHDGKIDKE 186 + L ++ D K F++ D ++ G I+ + Sbjct: 632 EAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELD 689 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 33/173 (19%), Positives = 57/173 (32%), Gaps = 19/173 (10%) Query: 28 GGLGDPELLARDTV-------FSVSEIEALYELFKKISSAVIDDGLINKEEFQL-ALFKT 79 G PE L+ T F + + F + + L E + + F+ Sbjct: 431 GIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEP 490 Query: 80 NKKESLFADRVFDLFDTKHNGI--LGFEEFARALSVF-HPNAPIDDKIHFSF-QLYDLKQ 135 NK D +F K + +E L F IDD + F QL + Sbjct: 491 NKD----GDFCIRVFSEKKADYQAVD-DEIEANLEEFDISEDDIDDGVRRLFAQL--AGE 543 Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 I E++ ++ LA+ D + + D+ GK+ +E+ Sbjct: 544 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 596 Score = 27.3 bits (59), Expect = 5.0, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 38/96 (39%), Gaps = 9/96 (9%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 ++I+ +++++I V G +N E + AL + K +V I+ F Sbjct: 601 TKIQKYQKIYREID--VDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDF 658 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIE 140 + F R L + + F+ D + G IE Sbjct: 659 DNFVRCLVRL-------ETLFKIFKQLDPENTGTIE 687 >3DF0-A nrPDB Length = 714 Score = 34.3 bits (77), Expect = 0.047, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 40/118 (33%), Gaps = 28/118 (23%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + D+ D +G LG +EF + K ++ D+ + G + E+++ + Sbjct: 580 MVDMLDEDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALE 632 Query: 150 ATLAESGMNLKDTVIEDIID---------------------KTFEEADTKHDGKIDKE 186 + L ++ D K F++ D ++ G I + Sbjct: 633 EAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLD 690 Score = 32.3 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 20/54 (37%) Query: 135 QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 + I E++ ++ LA+ D + + D GK+ +E+ Sbjct: 544 EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 Score = 26.9 bits (58), Expect = 7.6, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 ++I+ +++++I V G +N E + AL + K +V I+ F Sbjct: 602 TKIQKYQKIYREID--VDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDF 659 Query: 105 EEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 + F R L + + F+ D + G I Sbjct: 660 DNFVRCLVRL-------EILFKIFKQLDPENTGTI 687 >2M1U-A nrPDB Length = 93 Score = 34.3 bits (77), Expect = 0.048, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 32/74 (43%), Gaps = 11/74 (14%) Query: 120 IDDK--IHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADT 177 D+K + +F +D GF+ +E + ++ + E I + FE AD Sbjct: 22 SDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIR---------DGLPMTEAEITEFFEAADP 72 Query: 178 KHDGKIDKEEWRSL 191 + G ID + + ++ Sbjct: 73 NNTGFIDYKAFAAM 86 Score = 31.9 bits (71), Expect = 0.22, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 2/67 (2%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 E L E F DG ++ EEF+ + F+ D + G + + Sbjct: 23 DEKTQLIEAFYNFD--GDYDGFVSVEEFRGIIRDGLPMTEAEITEFFEAADPNNTGFIDY 80 Query: 105 EEFARAL 111 + FA L Sbjct: 81 KAFAAML 87 >4C0K-A nrPDB Length = 423 Score = 34.3 bits (77), Expect = 0.050, Method: Composition-based stats. Identities = 24/162 (14%), Positives = 57/162 (35%), Gaps = 18/162 (11%) Query: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALF--KTNKKESLFADRVFDL 93 + + + + ++L +FK + D L+N E L + D V + Sbjct: 1 MMEEQELTSACKKSLVRIFKICD--IDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAV 58 Query: 94 FDTK-----HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEV-KQM 147 +N + + F +F ++ ++ L++ G+ ++ E+ ++ Sbjct: 59 IQKNVPDGIYNDAVTLKGFLFLHCLFIQRG--RNETTWAV----LRRFGYNDQLEMCQEY 112 Query: 148 VVATLAESGMNLKDTVI--EDIIDKTFEEADTKHDGKIDKEE 187 + L + + + + FE D DG + EE Sbjct: 113 LRPPLKIPPGSSTELSHRGQQFLIAVFERYDRDGDGALSPEE 154 >6AGI-A nrPDB Length = 382 Score = 33.9 bits (76), Expect = 0.054, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 45 SEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGF 104 +E +++ K+ + + G+I+ E+ L L K F++FDT N ++ Sbjct: 66 AETPPVWKGSSKLFRNLKEKGVISYTEY-LFLLCILTKPHAGFRIAFNMFDTDGNEMVDK 124 Query: 105 EEFARALSVFHPNAPIDD 122 +EF +F + Sbjct: 125 KEFLVLQEIFRKKNEKRE 142 Score = 31.2 bits (69), Expect = 0.33, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 41/91 (45%), Gaps = 5/91 (5%) Query: 60 AVIDDGLINKEEFQ-LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 ++ ++ I +EF+ F N ++ A +++ + +G +EF RA+ V Sbjct: 284 SIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNF----ASRSIGQDEFKRAVYVATGLK 339 Query: 119 PIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 ++ F+++D+ + + +E ++ Sbjct: 340 FSPHLVNTVFKIFDVDKDDQLSYKEFIGIMK 370 Score = 31.2 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 6/47 (12%), Positives = 18/47 (38%), Gaps = 3/47 (6%) Query: 99 NGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVK 145 G++ + E+ L + +F ++D ++++E Sbjct: 85 KGVISYTEYLFLLCILT---KPHAGFRIAFNMFDTDGNEMVDKKEFL 128 Score = 30.8 bits (68), Expect = 0.47, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 32/93 (34%), Gaps = 9/93 (9%) Query: 35 LLARDTVFSVSEIEALYELFKKISSAVIDDGL-------INKEEFQLALFKTNKK--ESL 85 + + + E + ++ + I + I ++EF+ A++ Sbjct: 284 SIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPH 343 Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNA 118 + VF +FD + L ++EF + Sbjct: 344 LVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRG 376 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 48/132 (36%), Gaps = 18/132 (13%) Query: 65 GLINKEEFQLALFKTNKKESL--FADRVFDLFDTKHNGILG-FEEFARALSVFHPNAPID 121 I++E+F L + E+ F + V + F F + L+ Sbjct: 254 NTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNL------- 306 Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + + +Y+ + I + E K+ A +G+ +++ F+ D D Sbjct: 307 EDFAIALNMYNFASR-SIGQDEFKR---AVYVATGLKFSP----HLVNTVFKIFDVDKDD 358 Query: 182 KIDKEEWRSLVL 193 ++ +E+ ++ Sbjct: 359 QLSYKEFIGIMK 370 >6DS2-B nrPDB Length = 114 Score = 33.9 bits (76), Expect = 0.055, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 67 INKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHF 126 + +++ Q L K NK E + + + + DT + L FEEF ++ +K+H Sbjct: 40 LVRKDLQNFLKKENKNEKVI-EHIMEDLDTNADKQLSFEEFIMLMARLTWA--SHEKMHE 96 Score = 32.7 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 2/57 (3%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + + E K++V L K+ E +I+ E+ DT D ++ EE+ L+ R Sbjct: 31 TLNQGEFKELVRKDLQNFLK--KENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 >5CSF-A nrPDB Length = 95 Score = 33.9 bits (76), Expect = 0.062, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 +++ E+K+++ L+ +K+ ++++DK E D DG+ D +E+ + V Sbjct: 30 KLKKSELKELINNELSHFLEEIKE---QEVVDKVMETLDNDGDGECDFQEFMAFV 81 Score = 31.2 bits (69), Expect = 0.33, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 20/44 (45%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHP 116 +L+ F KE D+V + D +G F+EF +++ Sbjct: 43 ELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTT 86 >5HYD-A nrPDB Length = 99 Score = 33.5 bits (75), Expect = 0.076, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + + E+K ++ L E K+T + +DK ++ D D ++D E+ +V Sbjct: 28 KLSKGELKLLLQRELTEFLSCQKETQL---VDKIVQDLDANKDNEVDFNEFVVMV 79 Score = 32.3 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 19/43 (44%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFH 115 +L F + +KE+ D++ D + + F EF ++ Sbjct: 41 ELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALT 83 >3CS1-A nrPDB Length = 219 Score = 33.5 bits (75), Expect = 0.077, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 46/168 (27%), Gaps = 34/168 (20%) Query: 37 ARDTVFSVSEIEALYELFKK-----ISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 91 T + L++ F K + + G + K ++ S D Sbjct: 40 REKTAEAKQRRIELFKKFDKNETGKLCYDEVYSGCLEV-------LKLDEFTSRVRDITK 92 Query: 92 DLFDTK-----------HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIE 140 FD + F EF L + ++ F D ++ Sbjct: 93 RAFDKSRTLGSKLENKGSEDFVEFLEFRLMLCYIYDFF----ELTVMFDEIDASGNMLVD 148 Query: 141 RQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 +E K+ V A + F+E D G + +E+ Sbjct: 149 EEEFKRAVPKLEAWGAKVEDPAAL-------FKELDKNGTGSVTFDEF 189 Score = 32.3 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 3/79 (3%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 +FD D N ++ EEF RA+ + F+ D G + E Sbjct: 135 MFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFAAWAS 194 Query: 150 ATLAES---GMNLKDTVIE 165 A ++ N+ ++ +E Sbjct: 195 AVKLDADGDPDNVPESALE 213 >2AUC-A nrPDB Length = 126 Score = 33.5 bits (75), Expect = 0.084, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 38/94 (40%), Gaps = 10/94 (10%) Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 L +E++ L++ + +++ F +D GF+ + ++K ++ G L Sbjct: 43 DSLTYEQYLEYLTMCVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTT----WGDAL 98 Query: 160 KDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 + D ++ E +I+ + + +L Sbjct: 99 TEQEANDALNAFSSE------DRINYKLFCEDIL 126 >2KGR-A nrPDB Length = 111 Score = 33.5 bits (75), Expect = 0.085, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 38/88 (43%), Gaps = 4/88 (4%) Query: 89 RVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQE-VKQM 147 ++F+ D +G L +A ++ ++ ++ + L D+ Q G + +E + M Sbjct: 18 QLFNSHDKTMSGHLTGP---QARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 74 Query: 148 VVATLAESGMNLKDTVIEDIIDKTFEEA 175 + +A SG L + + I +F Sbjct: 75 HLIDVAMSGQPLPPVLPPEYIPPSFRRV 102 Score = 32.3 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 14/95 (14%), Positives = 33/95 (34%), Gaps = 10/95 (10%) Query: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 K F +D G + + + ++ ++ ++ + + + +D DGK Sbjct: 15 KYRQLFNSHDKTMSGHLTGPQARTIL----------MQSSLPQAQLASIWNLSDIDQDGK 64 Query: 183 IDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSF 217 + EE+ + + L + PSF Sbjct: 65 LTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSF 99 >4FTG-A nrPDB Length = 96 Score = 32.7 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + + F+F + + G++ +++++ ++ N KD + +DK ++ D DG Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPL---AVDKIMKDLDQCRDG 64 Query: 182 KIDKEEWRSLV 192 K+ + + SL+ Sbjct: 65 KVGFQSFFSLI 75 >3H4S-E nrPDB Length = 135 Score = 32.7 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 40/98 (40%), Gaps = 8/98 (8%) Query: 104 FEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTV 163 +E+ ++ ++ F L ++ I + +++ SG+ + + Sbjct: 22 YEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESLRR-------NSGILGIEGM 74 Query: 164 IEDIIDKTFEEADTKHDGKIDKEEWRSLVLR-HPSLLK 200 ++ E D DG +++ E+ L++R P +++ Sbjct: 75 SKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMME 112 >4HRG-A nrPDB Length = 115 Score = 32.7 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 122 DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDG 181 + + F+F + + G++ +++++ ++ N KD + +DK ++ D DG Sbjct: 11 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPL---AVDKIMKDLDQCRDG 66 Query: 182 KIDKEEWRSLV 192 K+ + + SL+ Sbjct: 67 KVGFQSFFSLI 77 >2MHH-A nrPDB Length = 96 Score = 32.7 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 21/53 (39%), Gaps = 3/53 (5%) Query: 95 DTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQM 147 D + L F+E+ + L D I F YD+ ++ +E +M Sbjct: 28 DANADQHLDFDEWRQELKC---RGHADADIEAVFAKYDVDGDRVLDAEEQMKM 77 >2Y5I-A nrPDB Length = 99 Score = 32.7 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 29/52 (55%), Gaps = 3/52 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + + E+K+++ A L + M+ KD ++ ++K + D+ D ++D E+ Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDPML---VEKIMNDLDSNKDNEVDFNEFV 76 Score = 30.4 bits (67), Expect = 0.60, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 47 IEALYELFKKISSAVIDDGLINKEEFQ------LALFKTNKKESLFADRVFDLFDTKHNG 100 ++AL +F S + D ++K E + L F ++K+ + +++ + D+ + Sbjct: 9 MDALITVFHNYSGSEGDKYKLSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDN 68 Query: 101 ILGFEEFARALSVFH 115 + F EF ++ Sbjct: 69 EVDFNEFVVLVAALT 83 >2MJW-B nrPDB Length = 94 Score = 32.3 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 25/69 (36%), Gaps = 6/69 (8%) Query: 54 FKKISSAVIDDGLINKEEFQLAL------FKTNKKESLFADRVFDLFDTKHNGILGFEEF 107 F + S + + K E ++ + F + K+ D++ D + + F EF Sbjct: 15 FSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEF 74 Query: 108 ARALSVFHP 116 ++ Sbjct: 75 IVFVAAITS 83 Score = 32.3 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 24/55 (43%), Gaps = 3/55 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 + + E+K V E L+ +D +DK ++ D D ++D E+ V Sbjct: 27 TLTKGELK---VLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFV 78 >4AOM-A nrPDB Length = 146 Score = 32.3 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 24/51 (47%) Query: 100 GILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVA 150 L +E++ LS+ + +++ F +D G++ + ++K ++ Sbjct: 62 DNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTT 112 >1KFX-S nrPDB Length = 184 Score = 31.9 bits (71), Expect = 0.20, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 42/129 (32%), Gaps = 34/129 (26%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFS--FQLYDLKQQGFIERQEVKQM 147 + + D+ G LGFEEF + + ++ +D + G I E+ Sbjct: 63 MVAVMDSDTTGKLGFEEFKYLWNNIK---------RWQAIYKQFDTDRSGTICSSELPGA 113 Query: 148 VVATLAESGMNLKDTVIEDIID---------------------KTFEEADTKHDGKI--D 184 A +L + +I D + F+ D G+I + Sbjct: 114 FEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 173 Query: 185 KEEWRSLVL 193 +EW L + Sbjct: 174 IQEWLQLTM 182 >2JXC-A nrPDB Length = 100 Score = 31.6 bits (70), Expect = 0.31, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 10/57 (17%) Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 GF+ +VK ++ L + DI+ + +E +D HDG +D++E+ + Sbjct: 28 NGFLSGDKVKPVL----------LNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >1WY9-A nrPDB Length = 147 Score = 31.6 bits (70), Expect = 0.31, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 36/97 (37%), Gaps = 13/97 (13%) Query: 114 FHPNAPIDDKIHFSFQL----YDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIID 169 + + + K+ +F++ +DL G I+ +K+M+ L + Sbjct: 37 YSNDEDLPSKLE-AFKVKYMEFDLNGNGDIDIMSLKRML--------EKLGVPKTHLELK 87 Query: 170 KTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQY 206 + E + + ++ ++L S + M L Y Sbjct: 88 RLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMY 124 >5X2E-A nrPDB Length = 80 Score = 31.6 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 22/53 (41%), Gaps = 3/53 (5%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQ 142 +F D ++ + E + ++ + + + +K QL+D G I + Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSMVEKWK---QLFDPDNTGSITLE 55 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 10/69 (14%) Query: 128 FQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 F D I E++Q V + NL + +++K + D + G I E Sbjct: 7 FVSIDKDGTNVISYPELEQYV------AENNLDPS----MVEKWKQLFDPDNTGSITLET 56 Query: 188 WRSLVLRHP 196 + S + P Sbjct: 57 FCSKLGLKP 65 >5HLO-A nrPDB Length = 94 Score = 30.8 bits (68), Expect = 0.49, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 17/30 (56%) Query: 165 EDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + D F+E D DG ++ +E+ LV++ Sbjct: 49 KKGADVWFKELDINTDGAVNFQEFLILVIK 78 Score = 26.9 bits (58), Expect = 7.4, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 16/50 (32%), Gaps = 2/50 (4%) Query: 79 TNKKESLFADRVFDLFDTKHNGILGFEEFARALSV--FHPNAPIDDKIHF 126 AD F D +G + F+EF + + ++ H Sbjct: 44 PQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHK 93 >1NUB-A nrPDB Length = 229 Score = 30.8 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 24/66 (36%), Gaps = 11/66 (16%) Query: 124 IHFSFQLYDLKQ-QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 +H+ F D G++ E+ + + +E + FE D +D Sbjct: 157 VHWQFGQLDQHPIDGYLSHTEL----------APLRAPLIPMEHCTTRFFETCDLDNDKY 206 Query: 183 IDKEEW 188 I +EW Sbjct: 207 IALDEW 212 >3TQO-A nrPDB Length = 462 Score = 30.4 bits (67), Expect = 0.58, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 46/118 (38%), Gaps = 13/118 (11%) Query: 17 GCFDLDLYKQSGGLGDPELLARDTVFSVSEIEAL------YELFKKISSAVIDDGLINKE 70 G +++ K S LG+ + S E+ Y S +++G + E Sbjct: 261 GLLEINKEKMSKSLGNIISIREALKESDVEVLRYFLLSGHYRNPLSYSKENLENGRLALE 320 Query: 71 EFQLALFK----TNKKESLFADRVFDLFDTKHNGILGFE---EFARALSVFHPNAPID 121 F LAL ++K S + DR ++ D N + F E R ++ F N I+ Sbjct: 321 RFYLALRGLPVVNHEKTSSYTDRFYEAMDDDFNTPIAFALLFEMVREINRFRDNNQIE 378 >2VTG-A nrPDB Length = 150 Score = 30.4 bits (67), Expect = 0.71, Method: Composition-based stats. Identities = 18/124 (14%), Positives = 40/124 (32%), Gaps = 12/124 (9%) Query: 105 EEFARALSVFHPNAPIDDKI---HFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 161 EF + + +K+ + +DL +G I+ +K+M+ L Sbjct: 31 REFLCD-QKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMM--------EKLGV 81 Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTFPSFVFHS 221 + K E I ++ +++L S + + + + + P V Sbjct: 82 PKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEGKANESSPKPVGPP 141 Query: 222 QVED 225 D Sbjct: 142 PERD 145 >2JQ6-A nrPDB Length = 139 Score = 30.0 bits (66), Expect = 0.79, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 10/53 (18%) Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 G I K+ +V K + ++ K ++ AD DG +D EE+ Sbjct: 64 NGKITGANAKKEMV----------KSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >5W1A-B nrPDB Length = 155 Score = 30.0 bits (66), Expect = 0.82, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 40/103 (38%), Gaps = 12/103 (11%) Query: 102 LGFEEFARALSVFHPNAPID--DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNL 159 + +EF S + +LYD ++ G + E++ ++A L Sbjct: 61 IKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLA--------L 112 Query: 160 KDTVIEDIIDKTFEE-AD-TKHDGKIDKEEWRSLVLRHPSLLK 200 +++ ++ ++ F + D +G I + + + P LK Sbjct: 113 GESLDDEQVETLFADCMDPEDDEGFIPYSPFLARMCDRPDQLK 155 >2KFH-A nrPDB Length = 105 Score = 30.0 bits (66), Expect = 0.92, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 10/53 (18%) Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 G I K+ +V K + ++ K ++ AD DG +D EE+ Sbjct: 30 NGKITGANAKKEMV----------KSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >1NP8-A nrPDB Length = 159 Score = 29.6 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 32/90 (35%), Gaps = 8/90 (8%) Query: 90 VFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVV 149 + + D+ G LGFEEF + K ++ +D + G I E+ Sbjct: 59 MVAVMDSDTTGKLGFEEFKYLWNNI-------KKWQGIYKRFDTDRSGTIGSNELPGAFE 111 Query: 150 ATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 A ++ +I D+T D + Sbjct: 112 AAGFHLNQHIYSMIIRRYSDET-GNMDFDN 140 >4MDC-A nrPDB Length = 252 Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 33/80 (41%), Gaps = 2/80 (2%) Query: 6 DGIKHLCTSVLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDG 65 D ++ LC + + LD + SG + L + F +EI L E F + A + Sbjct: 78 DSMRALCGATIISEYLD--ETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRP 135 Query: 66 LINKEEFQLALFKTNKKESL 85 L+ + F+L + + Sbjct: 136 LVRERIFKLQMTPDQGGGAP 155 >4I5L-B nrPDB Length = 413 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 43/121 (35%), Gaps = 15/121 (12%) Query: 91 FDLFDTKHNGILGFEEFAR----ALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 F DT H+ ++ ++ AR ALS + + ++ +++G I + Sbjct: 204 FWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKV---QKEGKISYADFVW 260 Query: 147 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQY 206 +++ +D I+ F D DG + E L +M ++ Sbjct: 261 FLIS--------EEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEA 312 Query: 207 L 207 L Sbjct: 313 L 313 >1SRA-A nrPDB Length = 151 Score = 29.2 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 24/66 (36%), Gaps = 11/66 (16%) Query: 124 IHFSFQLYDLKQ-QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 +H+ F D G++ E+ + + +E + FE D +D Sbjct: 79 VHWQFGQLDQHPIDGYLSHTEL----------APLRAPLIPMEHCTTRFFETCDLDNDKY 128 Query: 183 IDKEEW 188 I +EW Sbjct: 129 IALDEW 134 >4YBH-B nrPDB Length = 92 Score = 29.2 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 25/65 (38%), Gaps = 4/65 (6%) Query: 54 FKKISSAVIDDGLINKEEFQLALFKTNKKESLFAD----RVFDLFDTKHNGILGFEEFAR 109 F K S D ++K+E + + K S D R+ + D + + F+E+ Sbjct: 18 FHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVT 77 Query: 110 ALSVF 114 L Sbjct: 78 FLGAL 82 Score = 28.9 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 25/52 (48%), Gaps = 5/52 (9%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + ++E+K+++ G L+D I + E+ D D +++ +E+ Sbjct: 30 TLSKKELKELIQ-KELTIGSKLQDAE----IARLMEDLDRNKDQEVNFQEYV 76 >2NS2-A nrPDB Length = 242 Score = 29.2 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 7/79 (8%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 +L + + EV VAT S +L DT+I ++ FE D D EWR + Sbjct: 81 ELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAVEHMFETEDGSKD------EWRGM 134 Query: 192 VLRHPSLLKN-MTLQYLKD 209 VL ++ + Y KD Sbjct: 135 VLARAPVMNTWFYITYEKD 153 >1Z5V-A nrPDB Length = 474 Score = 29.2 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 8/72 (11%) Query: 162 TVIEDIIDKTFEEADTKHDGKIDKEEWR--------SLVLRHPSLLKNMTLQYLKDITTT 213 + E I + F+ D + DG E + + LL+ + +Y K + T Sbjct: 109 SQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQT 168 Query: 214 FPSFVFHSQVED 225 + F ++ D Sbjct: 169 YSVFPNQDEMSD 180 >1C4O-A nrPDB Length = 664 Score = 28.9 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 40/112 (35%), Gaps = 8/112 (7%) Query: 19 FDLDLYKQSGGLGDPELLARDTVFSVSEIEA----LYELFKKISSAVIDDGLINKEEFQL 74 +DL++ + G E AR F+ L + F + +D+ + + Q Sbjct: 286 YDLEMLRVMGTCPGVENYAR--YFTGKAPGEPPYTLLDYFPEDFLVFLDESHVTVPQLQG 343 Query: 75 ALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALS--VFHPNAPIDDKI 124 ++ D F L N L FEEF +S VF P ++ Sbjct: 344 MYRGDYARKKTLVDYGFRLPSALDNRPLRFEEFLERVSQVVFVSATPGPFEL 395 >2QPT-A nrPDB Length = 550 Score = 28.9 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 21/53 (39%), Gaps = 10/53 (18%) Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 G + A G L ++V+ + ++ +D DG +D EE+ Sbjct: 471 DGKLSGS------KAKTWMVGTKLPNSVLG----RIWKLSDVDRDGMLDDEEF 513 >1SNL-A nrPDB Length = 103 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 29/77 (37%), Gaps = 8/77 (10%) Query: 128 FQLYDLKQQGFIERQEVK--------QMVVATLAESGMNLKDTVIEDIIDKTFEEADTKH 179 F L+D+ G ++ QE++ ++ E M + + + + DT Sbjct: 26 FILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQ 85 Query: 180 DGKIDKEEWRSLVLRHP 196 D + EE+ + R Sbjct: 86 DRLVTLEEFLASTQRKE 102 >4MEW-A nrPDB Length = 356 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 43/121 (35%), Gaps = 15/121 (12%) Query: 91 FDLFDTKHNGILGFEEFAR----ALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 F DT H+ ++ ++ AR ALS + + ++ +++G I + Sbjct: 196 FWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKV---QKEGKISYADFVW 252 Query: 147 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQY 206 +++ +D I+ F D DG + E L +M ++ Sbjct: 253 FLIS--------EEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEA 304 Query: 207 L 207 L Sbjct: 305 L 305 >2KHN-A nrPDB Length = 121 Score = 28.5 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 21/43 (48%) Query: 163 VIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQ 205 + + ++ + + AD +DG++D+ E+ + L+ L Sbjct: 63 LPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLP 105 >4PEM-A nrPDB Length = 286 Score = 28.5 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 21/57 (36%), Gaps = 4/57 (7%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEE--FARALSVFHPNAPIDDKIHFSFQLYDLK 134 ++AD + LF G + ++ F ++ + + + +F +D Sbjct: 40 YGMPHIYADDTYRLFY--GYGYVVAQDRLFQMEMARRSTQGTVSEVLGKAFVSFDKD 94 >4PEL-A nrPDB Length = 222 Score = 28.5 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 21/57 (36%), Gaps = 4/57 (7%) Query: 80 NKKESLFADRVFDLFDTKHNGILGFEE--FARALSVFHPNAPIDDKIHFSFQLYDLK 134 ++AD + LF G + ++ F ++ + + + +F +D Sbjct: 40 YGMPHIYADDTYRLFY--GYGYVVAQDRLFQMEMARRSTQGTVSEVLGKAFVSFDKD 94 >1DJX-A nrPDB Length = 624 Score = 28.5 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 16/39 (41%) Query: 156 GMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 G + ++ I +AD D K++ +E + + Sbjct: 1 GSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKE 39 >5MKE-A nrPDB Length = 968 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 19/57 (33%), Gaps = 3/57 (5%) Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 G L F+E + L D +I F YD + E +QM E Sbjct: 732 GGGKLNFDELRQDLK---GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 785 >4CJ1-A nrPDB Length = 625 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 30/77 (38%), Gaps = 12/77 (15%) Query: 108 ARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDI 167 AL+ F +++ + D+ G + ++ ++ + ++ L + E Sbjct: 541 IYALAGFVNYNSPQNEVLYG----DVNDDGKVNSTDL-TLLKRYVLKAVSTLPSSKAE-- 593 Query: 168 IDKTFEEADTKHDGKID 184 + AD DG+++ Sbjct: 594 -----KNADVNRDGRVN 605 >4D10-D nrPDB Length = 410 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 56/157 (35%), Gaps = 32/157 (20%) Query: 83 ESLFADRVFDLFDTKHNGILGFEEFARAL-----------SVFHPNAPIDDKIHFSFQLY 131 E ++ DR+ N +EFA L S A I+ + + +LY Sbjct: 269 EKMYLDRIIR-----GN---QLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLY 320 Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 + I +E+ ++ A++ + E ++ ++ DG + E R Sbjct: 321 N-----NITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQI----DGIVHF-ETREA 370 Query: 192 VLRHPSLLKNMTLQ---YLKDITTTFPSFVFHSQVED 225 + ++++ Q L+ I+ T P + + Sbjct: 371 LPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQ 407 >5NF4-A nrPDB Length = 451 Score = 28.5 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 23/67 (34%), Gaps = 10/67 (14%) Query: 72 FQLALFKTNKKESLFADRVF-----DLFDTKHNGIL-----GFEEFARALSVFHPNAPID 121 FQ A+ + + V+ T + FE+ +L++ ++ Sbjct: 23 FQGAMRGVDPQPDPLQPDVYLLVNARAAHTNGEESINMDAEDFEDRVHSLAMLVFDSNTG 82 Query: 122 DKIHFSF 128 +K+ F Sbjct: 83 EKVAEHF 89 >6I8Y-A nrPDB Length = 222 Score = 28.5 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 7/79 (8%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 +L + + EV VAT S +L DT+I ++ FE D D EWR + Sbjct: 54 ELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAVEHMFETEDGSKD------EWRGM 107 Query: 192 VLRHPSLLKN-MTLQYLKD 209 VL ++ + Y KD Sbjct: 108 VLARAPVMNTWFYITYEKD 126 >4DUQ-A nrPDB Length = 98 Score = 28.5 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 24/51 (47%), Gaps = 3/51 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 + + E+K+++ E + + V E+ + K D D ++D +E+ Sbjct: 29 KLSKGEMKELL---HKELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEY 76 >6D1W-A nrPDB Length = 740 Score = 28.5 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 19/57 (33%), Gaps = 3/57 (5%) Query: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAE 154 G L F+E + L D +I F YD + E +QM E Sbjct: 680 GGGKLNFDELRQDLK---GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKE 733 >3FZI-A nrPDB Length = 265 Score = 28.1 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 29/62 (46%), Gaps = 3/62 (4%) Query: 73 QLALFKTNKKESLFADRVFDLFDTKHNGIL-GFEEFARALSVFHPNAP-IDDKIHFSFQL 130 +A++ SL + FDT+ + F++F +++ PN ++++ + + Sbjct: 70 GVAMYTKVPPSSLREGFGVERFDTEGRIQIADFDDFL-LYNIYFPNGKMSEERLKYKLEF 128 Query: 131 YD 132 YD Sbjct: 129 YD 130 >4W7S-A nrPDB Length = 463 Score = 28.1 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 22/57 (38%), Gaps = 1/57 (1%) Query: 144 VKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 +KQ+ L E+ + D ED + + D D ++++ P + K Sbjct: 207 MKQVETLVLDEADKMI-DLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEK 262 >5L0P-A nrPDB Length = 353 Score = 28.1 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 37/105 (35%), Gaps = 9/105 (8%) Query: 38 RDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFD-T 96 + FS+ I++ F+ A++ L+ KE+F+ + + D + Sbjct: 123 AENEFSLRPIDS--NTFEMNGKALL---LLTKEDFRYRSPHSGDVLYELLQHILKQRDGS 177 Query: 97 KHNGILGFEEFARALSVFHPNAPIDDKIHFS---FQLYDLKQQGF 138 +G + R ++ + + ++ F L + F Sbjct: 178 GGSGSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTF 222 >4H9M-A nrPDB Length = 840 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 14/36 (38%) Query: 38 RDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ 73 R F E + E F K + I+++E+ Sbjct: 245 RSKGFGHEEEKDASEGFTKEDPNCPFNTFIHRKEYA 280 >3S8P-A nrPDB Length = 273 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 23/60 (38%), Gaps = 5/60 (8%) Query: 44 VSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF---DLFDTKH 98 E++ + E FKK + E+ L K +E LF + VF +F T Sbjct: 72 QEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDS 131 >2JTT-A nrPDB Length = 90 Score = 27.7 bits (60), Expect = 4.0, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 26/52 (50%), Gaps = 5/52 (9%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + ++E+K+++ G L+D I ++D + D D +++ +E+ Sbjct: 28 TLSKKELKELIQ-KELTIGSKLQDAEIVKLMD----DLDRNKDQEVNFQEYI 74 Score = 26.6 bits (57), Expect = 9.6, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 25/65 (38%), Gaps = 4/65 (6%) Query: 54 FKKISSAVIDDGLINKEEFQLALFKTNKKESLFAD----RVFDLFDTKHNGILGFEEFAR 109 F K S D ++K+E + + K S D ++ D D + + F+E+ Sbjct: 16 FHKYSGKEGDKHTLSKKELKELIQKELTIGSKLQDAEIVKLMDDLDRNKDQEVNFQEYIT 75 Query: 110 ALSVF 114 L Sbjct: 76 FLGAL 80 >5ZWN-y nrPDB Length = 588 Score = 27.7 bits (60), Expect = 4.3, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 22/57 (38%), Gaps = 1/57 (1%) Query: 144 VKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLK 200 +KQ+ L E+ + D ED + + D D ++++ P + K Sbjct: 332 MKQVETLVLDEADKMI-DLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEK 387 >5MVF-A nrPDB Length = 523 Score = 27.3 bits (59), Expect = 4.8, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 10/53 (18%) Query: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 G I V A L ++V+ K ++ AD DG +D+EE+ Sbjct: 444 NGKISG------VNAKKEMVTSKLPNSVLG----KIWKLADCDCDGMLDEEEF 486 >2QXL-A nrPDB Length = 658 Score = 27.3 bits (59), Expect = 5.1, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 37/83 (44%), Gaps = 10/83 (12%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 D+ + R+E++++V L + + + K +A + ++D E Sbjct: 293 DVDVSSQLSREELEELVKPLL---------ERVTEPVTKALAQAKLSAE-EVDFVEIIGG 342 Query: 192 VLRHPSLLKNMTLQYLKDITTTF 214 R P+L ++++ + K ++TT Sbjct: 343 TTRIPTLKQSISEAFGKPLSTTL 365 >4A0G-A nrPDB Length = 831 Score = 27.3 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 20/44 (45%) Query: 120 IDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTV 163 I+ + +F+ + + +E K +VV +A G DT+ Sbjct: 455 IEIALKMAFRKFCVDHNFCEATEEEKHIVVKVIALRGSYHGDTL 498 >5FM1-C nrPDB Length = 473 Score = 27.3 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 24/63 (38%), Gaps = 8/63 (12%) Query: 169 DKTFEEADTKHDGKIDKEEWR--------SLVLRHPSLLKNMTLQYLKDITTTFPSFVFH 220 D + D + D + E ++ + +LL+ + +Y K I TT+ F Sbjct: 117 DDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPAR 176 Query: 221 SQV 223 S Sbjct: 177 SSE 179 >5Z6Z-A nrPDB Length = 153 Score = 27.3 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%), Gaps = 3/38 (7%) Query: 15 VLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYE 52 +L F+ D + G+ E LAR+T S I+ ++ Sbjct: 109 LLRAFEKDRF---PGIAAREELARETGLPESRIQIWFQ 143 >5Z2T-C nrPDB Length = 64 Score = 27.3 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%), Gaps = 3/38 (7%) Query: 15 VLGCFDLDLYKQSGGLGDPELLARDTVFSVSEIEALYE 52 +L F+ D + G+ E LAR+T S I+ ++ Sbjct: 20 LLRAFEKDRF---PGIAAREELARETGLPESRIQIWFQ 54 >4D0P-A nrPDB Length = 387 Score = 27.3 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 41/115 (35%), Gaps = 28/115 (24%) Query: 83 ESLFADRVFDLFDTKHNGILGFEEFARAL-----------SVFHPNAPIDDKIHFSFQLY 131 E ++ DR+ N +EFA L S A I+ + + +LY Sbjct: 289 EKMYLDRIIR-----GN---QLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLY 340 Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 + I +E+ ++ A++ + E ++ ++ DG + E Sbjct: 341 N-----NITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQI----DGIVHFE 386 >5VC2-A nrPDB Length = 424 Score = 27.3 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 18/45 (40%) Query: 131 YDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEA 175 Y + G+I+ +E ++ + E + +I K F E Sbjct: 150 YGVNLDGYIDYEEALKIAQSVKPEIIVCGFSAYPREIDFKKFREI 194 >6G18-t nrPDB Length = 475 Score = 27.3 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 48/122 (39%), Gaps = 10/122 (8%) Query: 26 QSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL 85 ++ G + + + SE E + + + GL++ E+ + K Sbjct: 169 KATGEEEGMDIQKSENEDDSEWEDVDDEKGDSNDDYDSAGLLSDED---CMSVPGKTHRA 225 Query: 86 FADRVFDLFDTKHNGILGFEEFARALSVFHPNAPI---DDKIHFSFQLYDLKQQGFIERQ 142 AD +F +TK F E++ SV N + D++ ++ YD + G ++ Sbjct: 226 IADHLFWSEETKSR----FTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDDEIGALDNA 281 Query: 143 EV 144 E+ Sbjct: 282 EL 283 >1QJT-A nrPDB Length = 99 Score = 27.3 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 16/26 (61%) Query: 163 VIEDIIDKTFEEADTKHDGKIDKEEW 188 + + I+ K ++ ADT G + K+E+ Sbjct: 42 LPDLILGKIWDLADTDGKGVLSKQEF 67 >4FL4-A nrPDB Length = 88 Score = 27.3 bits (59), Expect = 5.7, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 22/53 (41%), Gaps = 8/53 (15%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKID 184 D+ G + ++ ++ + ++ L + E + AD DG+++ Sbjct: 24 DVNDDGKVNSTDL-TLLKRYVLKAVSTLPSSKAE-------KNADVNRDGRVN 68 >2YY5-A nrPDB Length = 348 Score = 27.3 bits (59), Expect = 5.9, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 44/115 (38%), Gaps = 18/115 (15%) Query: 69 KEEFQLALFKTNKKESLFADRVFDLFDT---------KHNGILGFEEFARALSVFHPNAP 119 +++F+L L ++ +R+ DLFD NG++ ++ + A Sbjct: 172 QKKFKLKLRLPQFVQNKDTNRIMDLFDPTKKMSKSSKNQNGVIYLDDPKEVVVKKIRQAT 231 Query: 120 ID--DKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTF 172 D +KI F+ + Q G + ++ A L E + + ++ F Sbjct: 232 TDSFNKIRFASKT----QPGV---TNMLTILKALLKEPVNQSLTNQLGNDLEAYF 279 >3X0D-A nrPDB Length = 655 Score = 27.3 bits (59), Expect = 6.1, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 32/84 (38%), Gaps = 2/84 (2%) Query: 55 KKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVF 114 K G + QL+ KT++ L V FD +H + F+E +V Sbjct: 207 KDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVA 266 Query: 115 HPNAPIDDKIHFSFQLYDLKQQGF 138 H + ID + + D+ + G Sbjct: 267 HSSGTIDALLMWW--DIDMDRNGT 288 >2Y3N-B nrPDB Length = 71 Score = 26.9 bits (58), Expect = 6.3, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 11/56 (19%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 DL G I +V + + G N E+AD +DG I+ ++ Sbjct: 8 DLNGDGVINMADVMILAQSFGKAIG-NPG----------VNEKADLNNDGVINSDD 52 >5VP3-A nrPDB Length = 206 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 25/55 (45%), Gaps = 10/55 (18%) Query: 140 ERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 + +E+K M+ A V ++ F++ADT GK+++ E L + Sbjct: 144 DVEELKTMMKAF----------DVPQEAAYTFFQKADTDKTGKLERPELVHLFRK 188 >4I0B-A nrPDB Length = 222 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 7/32 (21%), Positives = 18/32 (56%) Query: 182 KIDKEEWRSLVLRHPSLLKNMTLQYLKDITTT 213 +I +++R L+ +P +L ++ Q + + T Sbjct: 109 EISYKKFRQLIQVNPDILMRLSAQMARRLQVT 140 >3KCC-A nrPDB Length = 260 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 7/32 (21%), Positives = 18/32 (56%) Query: 182 KIDKEEWRSLVLRHPSLLKNMTLQYLKDITTT 213 +I +++R L+ +P +L ++ Q + + T Sbjct: 147 EISYKKFRQLIQVNPDILMRLSAQMARRLQVT 178 >1FI6-A nrPDB Length = 92 Score = 26.6 bits (57), Expect = 8.5, Method: Composition-based stats. Identities = 5/19 (26%), Positives = 10/19 (52%) Query: 171 TFEEADTKHDGKIDKEEWR 189 +E +D DG + +E+ Sbjct: 48 IWELSDFDKDGALTLDEFC 66 >1L9X-A nrPDB Length = 315 Score = 26.6 bits (57), Expect = 8.6, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 13/30 (43%) Query: 112 SVFHPNAPIDDKIHFSFQLYDLKQQGFIER 141 S+ N +++K+ F + G IE Sbjct: 195 SLSVKNFTMNEKLKKFFNVLTTNTDGKIEF 224 >4U3S-B nrPDB Length = 184 Score = 26.6 bits (57), Expect = 8.8, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 19/53 (35%), Gaps = 11/53 (20%) Query: 135 QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 187 Q G I +++ ++ A G + D + D DG I E+ Sbjct: 128 QDGAINLEDILEICKAF----GTSSTDAKYQ-------VGLDLNRDGAISLED 169 >5LPU-C nrPDB Length = 104 Score = 26.6 bits (57), Expect = 9.1, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 21/52 (40%), Gaps = 3/52 (5%) Query: 138 FIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWR 189 + + E+K+++ E L E K D+ D ++D +E+ Sbjct: 31 KLNKSELKELLT---RELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYC 79 >4I5K-A nrPDB Length = 285 Score = 26.6 bits (57), Expect = 9.6, Method: Composition-based stats. Identities = 20/170 (11%), Positives = 45/170 (26%), Gaps = 46/170 (27%) Query: 84 SLFADRVFDLFDTKHNGILGFEE-----FARALSVFHPNAPIDDKIHF-----------S 127 + R+F + +G + E F + L++ I+ + Sbjct: 62 TTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCK 121 Query: 128 FQLYDLKQQGFIERQEVKQ---------MVVATLAESGMNLKDTVIEDI----------- 167 F D +I + ++ + ++ + + K E Sbjct: 122 FWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLI 181 Query: 168 ----------IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYL 207 I+ F D DG + E ++ M ++ L Sbjct: 182 SEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPL 231 >4UQF-A nrPDB Length = 202 Score = 26.6 bits (57), Expect = 9.6, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 23/67 (34%), Gaps = 10/67 (14%) Query: 132 DLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSL 191 D + I++Q++ V L G N + D + EE + Sbjct: 10 DDDDKEQIDKQKIADAVKVILEAVGENPDREGLIDTPMRVARM----------YEEVFAG 59 Query: 192 VLRHPSL 198 + + PS+ Sbjct: 60 LKKDPSV 66 >6GYL-Q nrPDB Length = 735 Score = 26.6 bits (57), Expect = 9.8, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 19/48 (39%), Gaps = 3/48 (6%) Query: 151 TLAESGMNLKDTVIEDIIDKTFEEADTK---HDGKIDKEEWRSLVLRH 195 E G+N E+ T E D DGK++ +E+ + R Sbjct: 657 IKQEEGLNSTVAEREETPAPTITEKDIIEAIGDGKVNIKEFGKFIRRK 704 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.135 0.359 Lambda K H 0.267 0.0417 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,611,259 Number of Sequences: 36641 Number of extensions: 336670 Number of successful extensions: 3462 Number of sequences better than 10.0: 356 Number of HSP's better than 10.0 without gapping: 352 Number of HSP's successfully gapped in prelim test: 162 Number of HSP's that attempted gapping in prelim test: 1471 Number of HSP's gapped (non-prelim): 1056 length of query: 226 length of database: 10,336,785 effective HSP length: 94 effective length of query: 132 effective length of database: 6,892,531 effective search space: 909814092 effective search space used: 909814092 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.5 bits)