BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8K2I4 (879 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6DDT-A nrPDB 1791 0.0 6BYC-A nrPDB 374 e-103 2WBK-A nrPDB 364 e-101 5N6U-A nrPDB 357 1e-98 4CVU-A nrPDB 317 1e-86 6D1P-A nrPDB 56 6e-08 3DEC-A nrPDB 52 9e-07 6D8G-A nrPDB 47 3e-05 3GM8-A nrPDB 47 5e-05 6DXU-D nrPDB 46 5e-05 6MVH-A nrPDB 46 7e-05 6ETZ-A nrPDB 45 2e-04 6D8K-A nrPDB 42 0.001 6MVF-A nrPDB 41 0.003 3CMG-A nrPDB 40 0.003 6ED1-A nrPDB 40 0.004 6ED2-A nrPDB 39 0.008 3HN3-A nrPDB 39 0.012 3FN9-A nrPDB 38 0.020 5Z1B-A nrPDB 37 0.025 6MVG-A nrPDB 37 0.029 6NCW-A nrPDB 37 0.050 6NCZ-A nrPDB 37 0.052 5T99-A nrPDB 36 0.072 5T9G-A nrPDB 34 0.25 6B6L-A nrPDB 33 0.58 4JKL-A nrPDB 33 0.63 5Z19-A nrPDB 32 1.3 4PU9-A nrPDB 32 1.3 5DMY-A nrPDB 31 1.9 5MMP-A nrPDB 31 2.3 3VUP-A nrPDB 30 3.8 4CUC-A nrPDB 30 4.1 1CT9-A nrPDB 30 4.9 2RCC-A nrPDB 30 5.5 4YPJ-A nrPDB 30 6.1 6D89-C nrPDB 29 8.4 >6DDT-A nrPDB Length = 868 Score = 1791 bits (4638), Expect = 0.0, Method: Compositional matrix adjust. Identities = 858/858 (100%), Positives = 858/858 (100%) Query: 22 SYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYS 81 SYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYS Sbjct: 11 SYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYS 70 Query: 82 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK 141 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK Sbjct: 71 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK 130 Query: 142 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI 201 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI Sbjct: 131 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI 190 Query: 202 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ 261 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ Sbjct: 191 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ 250 Query: 262 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV 321 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV Sbjct: 251 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV 310 Query: 322 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD 381 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD Sbjct: 311 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD 370 Query: 382 ANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR 441 ANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR Sbjct: 371 ANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR 430 Query: 442 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRP 501 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRP Sbjct: 431 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRP 490 Query: 502 FIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP 561 FIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP Sbjct: 491 FIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP 550 Query: 562 SFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYL 621 SFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYL Sbjct: 551 SFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYL 610 Query: 622 TQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLH 681 TQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLH Sbjct: 611 TQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLH 670 Query: 682 YFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVV 741 YFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVV Sbjct: 671 YFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVV 730 Query: 742 KAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLE 801 KAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLE Sbjct: 731 KAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLE 790 Query: 802 ANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPT 861 ANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPT Sbjct: 791 ANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPT 850 Query: 862 SKSELQQAFSVTSLTDTY 879 SKSELQQAFSVTSLTDTY Sbjct: 851 SKSELQQAFSVTSLTDTY 868 >6BYC-A nrPDB Length = 862 Score = 374 bits (960), Expect = e-103, Method: Compositional matrix adjust. Identities = 274/902 (30%), Positives = 416/902 (46%), Gaps = 98/902 (10%) Query: 22 SYSLSGSWRVSNGNGSLE----------LPATVPGYVHSALHQHGLIQDPYYRFNDLNYR 71 + +L G WRV G + LPA VPG V + L ++ DP+YR N+ + Sbjct: 5 AVTLDGGWRVRLVPGQEQGKTYPKAAAWLPAQVPGAVQTDLIAAKIVPDPFYRDNEGKIQ 64 Query: 72 WISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDIT 131 W L +W Y T F + + + V+L+FDG+DT AE+ N + DNMF + D Sbjct: 65 WAGLSDWQYQTRFTVDAATLKREHVELVFDGLDTFAEVTLNGKQLLSADNMFRQWRVDAK 124 Query: 132 NVVK-DVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPV---EQKGECHVNFIRKAQCS 187 +++K N L+++ S ++ + A Y +P E + ++RKA + Sbjct: 125 SLLKRGDNLLEVKLYSPIKKIQPWL-AKQPYALPGAYDSAFGDEPEARHSSTYVRKAPYN 183 Query: 188 FSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSV 247 F WDWGP + GIWKDVR+EA++ +D L +A A +++A D+ + +S Sbjct: 184 FGWDWGPRMVNAGIWKDVRVEAWDAVRVDGLHIAQQRVDAHSA---QVQAQLDLQAGRSG 240 Query: 248 GGQVTVAI----PQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNM 303 QVT+ + Q Q T D + Q V L V+I + W+P G+G Q Y Sbjct: 241 PVQVTLDVLGPDGQKVGQFTQDAVVDPGQNRVDLAVRI---ANPKRWFPAGYGAQDRYTF 297 Query: 304 TILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSF 363 G + R+V+L E K G S ING+PIF KG+N IP D+F Sbjct: 298 VASVRDADGDSQQIKRVTGLRSVELRRE--KDRFGKSMEIVINGIPIFAKGANLIPLDAF 355 Query: 364 QDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYP 423 +VT +R++ Q DANMN LR+WGGG Y+ D FY + DELGIM+WQDFMF A+ P Sbjct: 356 PARVTHERMRSTLQDARDANMNMLRMWGGGHYQDDYFYDVADELGIMIWQDFMFGGAVPP 415 Query: 424 TEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFH-------VNPRDMKT 476 + F + R+E QV+RL+ HPS+++W GNNE + NW V+P + Sbjct: 416 YDVEFRENTRQEAIEQVKRLRDHPSLVLWCGNNEVQTGWE-NWGDRVKFKQSVDPEERTR 474 Query: 477 YIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNY 536 TL+ R++V + D P+ A+SP + GD+H++ Sbjct: 475 IERGMTTLFGTVFREVVATYDSDVPYWATSPGTDFDGAAD--------QTNDGDMHYWK- 525 Query: 537 ADDCWNWKIFP-------KARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHE 589 W P R +SEYG QS+P T+ + D + + R H + Sbjct: 526 ---VWGGPALPVTEYLNVTPRFMSEYGLQSFPDMRTVRAFAEPGD--MDPESPVMRVHQK 580 Query: 590 ----DGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIV 645 +GN +++ ++ F P + F+ +YL+Q+MQA+ I SR + Sbjct: 581 FDKGNGNKRLMLYIRREFGEP------KDFESFVYLSQLMQAEGINIAASHLRASRPQ-- 632 Query: 646 DGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFARRFFAPLLPVGFE-DEGVFYV 704 +MG+LYWQLND+W SW+S++Y G+WK LHY ARRF+AP + D+G V Sbjct: 633 -----SMGSLYWQLNDVWPGASWSSVDYYGRWKALHYHARRFYAPEMIAALRNDKGQTEV 687 Query: 705 YGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVVKAGEAVVLFQMPVSELL----KR 760 VS D T LT R W + ++ ++ K E + + + K+ Sbjct: 688 SLVS----DRTTPLTAR---W---RMRVMGMDGKVLSKREEKASVNALSSQHVGNFSDKQ 737 Query: 761 CRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLEANITVNISQKGNVFVFDLE 820 G + + D + F + K L A I G+ + L Sbjct: 738 LLGSADPKRTYAVFELLDGDTLLSREVVFFAPAKQL-ALPAAKIDSQWRADGDGYALTLT 796 Query: 821 TSAVAPFVWLDVGSIPGRFSDNGF-LMIRKKLSVLFYPWKPTSK---SELQQAFSVTSLT 876 + +A VWL G + SDN F L+ + L+V + TSK ++LQ A V L Sbjct: 797 SDTLAREVWLSFGDVDATLSDNAFDLLPGEPLTV-----RVTSKAALAQLQSALQVRDLA 851 Query: 877 DT 878 T Sbjct: 852 AT 853 >2WBK-A nrPDB Length = 847 Score = 364 bits (935), Expect = e-101, Method: Compositional matrix adjust. Identities = 261/878 (29%), Positives = 420/878 (47%), Gaps = 73/878 (8%) Query: 25 LSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEF 84 L W S +PATVPG VH L H L+ +P+Y N+ +W+ ++W Y T F Sbjct: 11 LDTGWEFSQSGTEKWMPATVPGTVHQDLISHELLPNPFYGMNEKKIQWVENEDWEYRTSF 70 Query: 85 KIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVV-KDVNSLKLQ 143 + ++LIF+G+DT A++ N + K DNMF GY+ + +V+ K N L + Sbjct: 71 IVSEEQLNRDGIQLIFEGLDTYADVYLNGSLLLKADNMFVGYTLPVKSVLRKGENHLYIY 130 Query: 144 FRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVN-FIRKAQCSFSWDWGPSFPSQGIW 202 F S ++ Q A + P + E H++ F RKA S+ WDWG + G+W Sbjct: 131 FHSPIRQTLPQY-ASNGFNYPAD----NDHHEKHLSVFSRKAPYSYGWDWGIRMVTSGVW 185 Query: 203 KDVRIEAYNIAHLD--YLTFLPVYDNASQAWN-------IEIKASFDVASSKSVGGQVTV 253 + V + Y+IA + Y+ L + D ++ N + K +V + S+ G Sbjct: 186 RPVTLRFYDIATISDYYVRQLSLTDENARLSNELIVNQIVPQKIPAEVRVNVSLNGTTVT 245 Query: 254 AIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGL 313 + Q + LQ + L ++ V W P G G T Y+ + A + Sbjct: 246 EVKQ-------QVTLQPGINHITLPAEVTNPV---RWMPNGWGTPTLYDFSAQIACGDRI 295 Query: 314 KIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQ 373 E++ ++ RT++++ E K G SFYF++NG+P+F KG+N+IP D+ VT++R Q Sbjct: 296 VAEQSHRIGLRTIRVVNE--KDKDGESFYFEVNGIPMFAKGANYIPQDALLPNVTTERYQ 353 Query: 374 LLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVR 433 LF+ + +ANMN +R+WGGG YE + FY L DE GI+VWQDFMFA YP++P FL V Sbjct: 354 TLFRDMKEANMNMVRIWGGGTYENNLFYDLADENGILVWQDFMFACTPYPSDPTFLKRVE 413 Query: 434 KEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFH--VNPRDMKTYIDDYVTLYVKNIRK 491 E Y +RRL++H S+ +W GNNE AL F P + + Y L+ + + Sbjct: 414 AEAVYNIRRLRNHASLAMWCGNNEILEALKYWGFEKKFTPEVYQGLMHGYDKLFRELLPS 473 Query: 492 IVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYS--IQYGDIHFYNYADDCWNWKIFPKA 549 V D R ++ SSP E W + D ++ + YG F + D Sbjct: 474 TVKEFDSDRFYVHSSPYLANWGRPESWGTGDSHNWGVWYGKKPFESLDTDL--------P 525 Query: 550 RLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGT 609 R +S++G+QS+P T+ ++ ED+ S Q GN + ++ + +P+ Sbjct: 526 RFMSQFGFQSFPEMKTIAAFAAPEDYQIESEVMNAHQKSSIGNSLIRTYMERDYIIPE-- 583 Query: 610 DPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWA 669 +F+D +Y+ V+Q Q ++ E + R+R + MG LYWQLND W SW+ Sbjct: 584 ----SFEDFVYVGLVLQGQGMRHGLEAHRRNRP-------YCMGTLYWQLNDSWPVVSWS 632 Query: 670 SLEYGGKWKMLHYFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWS-SP 728 S++Y G WK LHY A+R FAP+L + VY +SD D Q+T+ + Sbjct: 633 SIDYYGNWKALHYQAKRAFAPVLINPIQQNDSLSVYLISD-RLDTMEQMTLEMKVVDFDG 691 Query: 729 KPLCSLVN-SSIVVKAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFS---P 784 K L + S+ V A + +++ + L T E C SF K+ Sbjct: 692 KTLGKKIQVHSLEVPANTSKCVYRAKLDGWL------TPEDCRRSFLKLILKDKSGHQVA 745 Query: 785 TNYHFLSSLKDAKGLLEANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGF 844 + HF KD + L +++ + Q L +S +A ++++ R+SDN F Sbjct: 746 ESVHFFRKTKDLQ-LPPTSVSYQMKQTDGKCELTLFSSMLAKDIFIETPLQGARYSDNFF 804 Query: 845 LMI---RKKLSVLFYPWKPTSKSELQQAFSVTSLTDTY 879 ++ RKK+ + P K + ++ + +TY Sbjct: 805 DLLPGERKKVIIT----SPRIKKGEELPVNIKHIRETY 838 >5N6U-A nrPDB Length = 836 Score = 357 bits (916), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 247/831 (29%), Positives = 415/831 (49%), Gaps = 74/831 (8%) Query: 24 SLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTE 83 L G W A VPG VH L ++GLI DP+ N+L +W+ ++W Y + Sbjct: 28 KLDGEWEFKAVKDKKWRKAKVPGCVHLDLMENGLIPDPFVGENELEVQWVEKEDWIYRKK 87 Query: 84 FKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNV-VKDVNSLKL 142 F++ ++ + L F+G+DT +EI N IG+TDNMF + F++ ++ V+ N L++ Sbjct: 88 FQVGKEFLKYSSIYLEFEGIDTFSEIYLNGKKIGETDNMFIAWEFNVKDLLVEGENELEV 147 Query: 143 QFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVN--FIRKAQCSFSWDWGPSFPSQG 200 + S + E ++K + P + G + F RKAQ SF WDWGP + G Sbjct: 148 RLFSPSKVLEERAKNY----------PYKLHGGDYSPRVFGRKAQYSFGWDWGPRLATSG 197 Query: 201 IWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLK- 259 IWK V+++ +N A L ++PV S N +I D+ +S+ V I K Sbjct: 198 IWKSVKLKGWNKARL-LDVWVPV---RSLGENAQINIELDIELQESIPVDVAFRISHKKP 253 Query: 260 -TQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKA 318 +Q L + + +K+ + I+ + W+PRG+G Q Y + ++ + G ++K Sbjct: 254 VLEQRLRFTLPEGRVFLKIPLTIKNP---KLWFPRGYGEQNLYTLQLVLLDEKGEVLDKV 310 Query: 319 AKVY-FRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQ 377 + + R V+L + + + G SF FKIN +P+F KG+NWIPADSF ++ + +LL Sbjct: 311 EERFGIRKVELFTQ--EDNKGESFVFKINNIPVFAKGANWIPADSFLPRIKEEDYRLLLI 368 Query: 378 SVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVT 437 +A +N LRVWGGGIYE D FY LCDELGIMVWQDFMFA A YP + FL V+KE Sbjct: 369 RAKEAGVNMLRVWGGGIYENDIFYELCDELGIMVWQDFMFACAEYPDDENFLNDVQKEAE 428 Query: 438 YQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSED 497 + ++RL++HPSI++W GNN N W+ + I Y + + + D Sbjct: 429 FVIKRLRNHPSIVLWCGNNCNHWGYYAKWWGEREKFWGEEI------YSRVLPDVCARLD 482 Query: 498 KSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIH----FYNYADDCWNWKIFPKARLVS 553 +RP+ SSP G DP S + GD H ++ + D +N + R +S Sbjct: 483 LTRPYWPSSPYGGK----------DPNSQEVGDRHNWEVWHGWID--FNGYLKDNGRFIS 530 Query: 554 EYGYQSWPSFSTLEK-VSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPL 612 E+G Q+ P T+ K ++S++++ SR +G +++ + HFK+ + + Sbjct: 531 EFGMQAPPVAETIRKFITSEKEYYPQSREMEFHNKAREGTERIIRYIAGHFKITEDMN-- 588 Query: 613 RTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLE 672 + IYL+Q++Q +KT E + + K HT G+L WQ ND W SW+ ++ Sbjct: 589 ----EYIYLSQIIQGLALKTGIEHWR-------NNKFHTSGSLIWQWNDCWPVVSWSIID 637 Query: 673 YGGKWKMLHYFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLC 732 Y K K +YF +R F + G V+GV+D + + ++ + + + Sbjct: 638 YYKKLKPSYYFVKRAFRDIKVNIEPRNGKLLVFGVNDTLEKFYGKIEYAISTFRGKRRGK 697 Query: 733 SLVNSSIVVKAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSS 792 V+ I + A +V+L + + ++ K +E V Y +K+ N +F + Sbjct: 698 KEVD--IEIPANSSVILGEFNLEDVDK-----FKEFFYVQLY--NEKDELIDQNEYFFAP 748 Query: 793 LKDAKGLLEANITVNISQ-KGNVFVFDLETSAVAPFVWLDVGSIPGRFSDN 842 + + L A + ++ + + N ++ ++E+ +A +W+ + + DN Sbjct: 749 FRHLE-LPNAVVVYSVKEIEENSYLLNIESDFLA--LWVSLKLENAEWEDN 796 >4CVU-A nrPDB Length = 942 Score = 317 bits (813), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 231/767 (30%), Positives = 352/767 (45%), Gaps = 103/767 (13%) Query: 5 LLLILALFRAGCVVAGPSYSLSGS--------WRVSNGNGSLELPATVPGYVHSALHQHG 56 L L L++F AG VA + S W V+N G++ +P P H LH G Sbjct: 7 LSLSLSIF-AGAAVATTESTGKASIHDLALQKWTVTNEYGNITVPGKFPSQAHLDLHAAG 65 Query: 57 LIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVK--LIFDGVDTVAEILFNNV 114 +I + ND + RWI+ NWTY++ K LS+ + L+FDG+DT A + F + Sbjct: 66 VIGESNNGLNDFDLRWIAAQNWTYTS--KPISGLSKHSDIATWLVFDGLDTYATVKFCDH 123 Query: 115 TIGKTDNMFTGYSFDITNVVKDVNS---LKLQFRSAVQYAECQSKAHTSYRVPPECP-PV 170 +G DN F + +D+++ + S L + F S + + + P P Sbjct: 124 IVGTPDNQFRQWFYDVSSALASCKSDPVLSINFGSVPRIINAINASDEVQHWPASVVYPF 183 Query: 171 EQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRI-------EAYNI-AHLD------ 216 E ++RK Q F WDWGP+F G W+ RI E Y++ +D Sbjct: 184 EYPNR---QWVRKEQNDFGWDWGPAFSPVGPWQPGRIVQLSKGGELYSLNTDIDIFRKGQ 240 Query: 217 YLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVK 276 + F P + + W + AS D + ++V I ++ + + + + + Sbjct: 241 FNNFAP---DQTAPW--VVNASLDFLGTLPKHASMSVIITDASDSRSV-LYSGKLEGVTQ 294 Query: 277 LLVKIRKDVAVET-----WWPRGHGNQTGYNMTILFALDGGLK--IEKAAKVYFRTVQL- 328 + + V ++ WWPR GNQ YN+T+ + G + +V FRT+ Sbjct: 295 SDMTVTGSVTIDAHKPKLWWPRDMGNQQLYNITVSVSSAGSKTPILVSQRRVGFRTILFS 354 Query: 329 --------IEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVV 380 I GI +PG +++F+ING + KG+N IP D+F +VTSDR+ LF SV Sbjct: 355 SGNITDAQIASGI--TPGNNWHFEINGHEFYAKGANLIPPDAFWPRVTSDRMNRLFDSVE 412 Query: 381 DANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQV 440 N N LRVW G Y D Y + DE G+++W +F F+ LYP F A+V E+TY V Sbjct: 413 SQNFNMLRVWSSGTYLPDWIYDIADERGVLLWSEFQFSDTLYPDSDDFKANVVGEITYNV 472 Query: 441 RRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSR 500 RRL H S+ W G NE E + +P + Y L++ + ++ + S Sbjct: 473 RRLNHHASLACWMGGNEFENLMLPIAQGADPATYPYVLGQYENLFITTLFNVLAANSHSI 532 Query: 501 PFIASSPTNGMKTMEEGWISYD---PYSIQ-----------YGDIHFYNYADDC-WNWKI 545 + S N GW+ D P I YGD FYNY ++ Sbjct: 533 SYSPCSANN-------GWLEIDLDLPVPIVERYYNTTSGHIYGDTDFYNYDTSVSFDTSA 585 Query: 546 FPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHED-------------GN 592 +P R +E+G+ S PS T ++ E+ ++NS + R HH G Sbjct: 586 YPVGRFANEFGFISMPSIQTWQQAVDPEELSFNSTTVILRNHHYPAGGLTRNIHNSTLGQ 645 Query: 593 HQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKG--- 649 +M V+ ++ P TDP+ F + TQ+ QA K+E +FY R G G Sbjct: 646 VEMTLAVERYYPTPDKTDPVANFSSWCHATQLFQADMYKSEIQFYRR-------GSGLPE 698 Query: 650 HTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFARRFFAPLLPVGF 696 +G+LYWQLNDIWQAP+WA LEY G+WK+L Y +RR + ++ F Sbjct: 699 RQLGSLYWQLNDIWQAPTWAGLEYDGRWKVLPYVSRRTYEHVIASAF 745 >6D1P-A nrPDB Length = 814 Score = 56.2 bits (134), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 44/194 (22%), Positives = 86/194 (44%), Gaps = 25/194 (12%) Query: 309 LDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADS-FQDKV 367 +D G + FR + E+G F +NG + L+G++ + + Sbjct: 291 IDNGDTLRTTQHFGFRHFRFEEKGP---------FYLNGERLLLRGTHRHEDHAGVGAAL 341 Query: 368 TSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEF-YALCDELGIMVWQDFMFASALYPTEP 426 T + ++ Q + + N +R+ G Y+Q LCDELG++VW++ + E Sbjct: 342 TEEMMRTEMQQIKEMGANFIRL---GHYQQSGIILRLCDELGLLVWEEIPWCRGGLGGE- 397 Query: 427 GFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYV 486 + R+ +T + + ++HPS+I+W NEN +W P D +T+ D + ++ Sbjct: 398 SYKNQARRMLTNMIEQHRNHPSVILWGLGNEN------DW----PGDFQTFEKDSIRAFM 447 Query: 487 KNIRKIVLSEDKSR 500 + + D +R Sbjct: 448 GELHDLAHRLDPTR 461 >3DEC-A nrPDB Length = 1000 Score = 52.4 bits (124), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 67/248 (27%), Positives = 104/248 (41%), Gaps = 49/248 (19%) Query: 304 TILFAL-DGGLKIEK--AAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPA 360 T+L L D G K+ + KV FRT + I+ G F ING+P+ +KG N Sbjct: 309 TLLLELKDAGGKVTEITGTKVGFRTSE-IKNG---------RFCINGVPVLVKGVNRHEH 358 Query: 361 DSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEF-YALCDELGIMVWQDFMFAS 419 V+ + ++ + + N+NT+R Y + Y LCD G+ V + S Sbjct: 359 SQLGRTVSKELMEQDIRLMKQHNINTVR---NSHYPAHPYWYQLCDRYGLYVIDEANIES 415 Query: 420 ALYPTEPGFLASVRKEVTY------QVRRL----KSHPSIIIWSGNNENEVAL----SVN 465 P AS+ K+ T+ + RR+ K+HPS++IWS NE + + + Sbjct: 416 HGMGYGP---ASLAKDSTWLPAHIDRTRRMYERSKNHPSVVIWSLGNEAGNGINFERTYD 472 Query: 466 WFHVNPRDMKTY---------IDDYVTLY--VKNIRKIVLSEDKSRPFIASSPTNGMKT- 513 W ++ D Y +Y V IR V+ +D RPFI + M Sbjct: 473 WLKSVEKNRPVQYERAEENYNTDIYCRMYRSVDVIRNYVVRKDIYRPFILCEYLHAMGNS 532 Query: 514 ---MEEGW 518 M+E W Sbjct: 533 CGGMKEYW 540 >6D8G-A nrPDB Length = 886 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 60/125 (48%), Gaps = 6/125 (4%) Query: 396 EQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGN 455 + D +CD+LG++ W++ + P PG+ + + + +R+ +HPSII W Sbjct: 366 QADALLEMCDKLGMLAWEEIPIID-IVPNTPGYGDNCERNLREMIRQHYNHPSIITWG-- 422 Query: 456 NENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTME 515 NE+ L + ++K ++ + L + +++ ED +R I++ +G + Sbjct: 423 YMNEILLVTQRKYKTEAELKPVLERTLAL-ANRLERVLKEEDSTR--ISTMAFHGSNSYN 479 Query: 516 EGWIS 520 E +S Sbjct: 480 ETGLS 484 >3GM8-A nrPDB Length = 801 Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 84/388 (21%), Positives = 141/388 (36%), Gaps = 71/388 (18%) Query: 80 YSTEFKIPFNLSEWQ--KVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDV 137 Y F IP S+W+ KV+++F+GV +E+ N +GK N + + +D+T Sbjct: 70 YRKTFTIP---SKWKNKKVQILFEGVYLNSEVWINGHWLGKRPNGYISFVYDLT------ 120 Query: 138 NSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFP 197 P Q+G+ + + + W + Sbjct: 121 -------------------------------PYLQEGKNQIAVKVDHSKALTGRW---YT 146 Query: 198 SQGIWKDVRIEAYNIAHLDY--LTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAI 255 GI++ V + N H+ Y + F N A + + K + + + Sbjct: 147 GSGIYRPVYLLVSNPTHIPYSGIHFRSKLQNKQSA-TYTLSIEIETQEKKPIKVKTYLQA 205 Query: 256 PQLKTQQTND-IELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLK 314 P T++ I + + L IRK + W P + Y + D + Sbjct: 206 PNGSIADTSEKIFVSSADSLCFLSGSIRKPL---LWSPD---SPNVYTLICQLTRDNKIL 259 Query: 315 IEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG-SNWIPADSFQDKVTSDRLQ 373 E V FR QL + G F +NG + +KG + + V D L Sbjct: 260 DECRLPVGFR--QLEFNPVSG-------FLLNGKSLKIKGVCDHHTVGAVGAAVPDDLLH 310 Query: 374 LLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFA----SALYPTEPGFL 429 + + D N +R FY LCD +GIMV + + A F Sbjct: 311 YRLKLLKDMGCNAIRTSHNPF--SPAFYNLCDTMGIMVLNEGLDGWNQPKAADDYGNYFD 368 Query: 430 ASVRKEVTYQVRRLKSHPSIIIWSGNNE 457 +K++T ++R ++HPSII+WS NE Sbjct: 369 EWWQKDMTDFIKRDRNHPSIIMWSIGNE 396 >6DXU-D nrPDB Length = 830 Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 12/109 (11%) Query: 393 GIYEQDEF-YALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIII 451 G Y+Q E LCDELGI+VW++ + + + R+ + + + +HP++II Sbjct: 366 GHYQQSEIILDLCDELGILVWEEIPWCRGGLGGDV-YKKQARRMLANMIVQHHNHPAVII 424 Query: 452 WSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSR 500 W NEN+ W P D T+ + ++K + + D +R Sbjct: 425 WGLGNEND------W----PNDFNTFDKSAIRAFMKELHDMAHRLDDTR 463 >6MVH-A nrPDB Length = 780 Score = 46.2 bits (108), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 68/279 (24%), Positives = 115/279 (41%), Gaps = 48/279 (17%) Query: 200 GIWKDVRIEAYNIAH--LDY-----LTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVT 252 G+++DV I A N +H LDY + P A + +E+ + A K V T Sbjct: 163 GLYRDVNIIAVNKSHFDLDYYGGPGIKVTPEIKGADASVEVEVFLTNAAADQKLV---YT 219 Query: 253 VAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGG 312 V + K + + + ++ + AV W +G + Y T AL G Sbjct: 220 VKDAEGKEVAKTETAAGETKAVLSI-------PAVHLW----NGKKDPYLYTAEVALVSG 268 Query: 313 LKIEKAAKVYF--RTVQLIEEGIKGSPGLSFYFKINGLPIFLKG-----SNWIPADSFQD 365 + A F RT ++ E +G F +NG L+G W ++ Sbjct: 269 EEAVDAVSTRFGCRTFEIDPE--RG-------FILNGEEYPLRGVSRHQDRWGIGNALLP 319 Query: 366 KVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPT 424 + + + L + + T+R+ Y+ D+ FY LCDE G+++W + + S+ P Sbjct: 320 EHHREDIDL----ICELGATTIRL---AHYQHDQYFYDLCDERGLVIWAEIPYISSHMPN 372 Query: 425 EPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALS 463 S KE+ Q +HPSI++W +NE +A S Sbjct: 373 GRENTISQMKELVVQNY---NHPSIVVWGLSNEITMAGS 408 >6ETZ-A nrPDB Length = 989 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 84/386 (21%), Positives = 143/386 (37%), Gaps = 117/386 (30%) Query: 98 LIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVV-KDVNSLKLQFR--SAVQYAECQ 154 L FDG+++ + N V +G T + FD++ ++ + N+L ++ SA Y E Q Sbjct: 126 LRFDGIESAGTVWLNGVELGTTRGSRLAHEFDVSGILEQGENTLAVRVAQFSAASYVEDQ 185 Query: 155 SKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAH 214 W W P GI++DV ++A A Sbjct: 186 DM---------------------------------W-WLP-----GIFRDVTLQARPAAG 206 Query: 215 LDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQV---TVAIPQLKTQQTNDIELQQE 271 +D + YD+ + ++++AS GGQ V +P+L + E++ Sbjct: 207 IDDVFVHAGYDHITGEGILKVEASR--------GGQAIDAVVRVPELALELAAGTEVRVP 258 Query: 272 QRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAA-KVYFRTVQLIE 330 AVE W + L+ E A ++ FR++ + + Sbjct: 259 --------------AVEPW---------SAEVPKLYEAAVSAAGESVALQIGFRSIAIED 295 Query: 331 EGIKGSPGLSFYFKINGLPIFLKGSNW----------IPADSFQDKVTSDRLQLLFQSVV 380 FK+NG I L+G N +P D V L+L+ Q Sbjct: 296 A----------QFKVNGRRILLRGVNRHEHHPRLGRVVPRD-----VVEAELRLMKQH-- 338 Query: 381 DANMNTLRVWGGGIYEQDEFYALCDELGIMV-----WQDFMFASALYPT----EPGFLAS 431 N+N +R +F AL D+LG V + F SA + +P + + Sbjct: 339 --NINAIRT--SHYPPHPQFLALADQLGFYVVLECDLETHGFESAGWAQNPSDDPQWEDA 394 Query: 432 VRKEVTYQVRRLKSHPSIIIWSGNNE 457 + + V R K+H S+++WS NE Sbjct: 395 LVDRMRRTVERDKNHASVVMWSLGNE 420 >6D8K-A nrPDB Length = 597 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 75/348 (21%), Positives = 150/348 (43%), Gaps = 50/348 (14%) Query: 243 SSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYN 302 S K G ++TV+IP+LKT + D+ E + + + I+K +E W N Y Sbjct: 223 SDKKAGEKITVSIPELKT--SIDMLTDAEGK-AETVFNIKK---LERW---SSENPKLYE 273 Query: 303 MTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNW---IP 359 + + A D ++E+ ++ FR + + G Y +NG P F+ ++ IP Sbjct: 274 VIVSSAND---RVEE--QIGFRNITV--------KGTDIY--LNGKPTFMCSISFHEEIP 318 Query: 360 ADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYA-LCDELGIMVWQDFMFA 418 + +D LL ++ +N +R+ Y Q+E+ L +++G ++WQ+ Sbjct: 319 QRMGRAFSEADAAMLLNEAKA-LGVNMIRL---AHYPQNEYTVRLAEKMGFILWQEIPVW 374 Query: 419 SALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYI 478 + T ++ ++ ++R ++ ++ W NE + + + N F + + + Sbjct: 375 QGIDFTNNNTRKKAQRMLSEMIKRDQNRCAVGYWGIANETQPSKARNEFLTSLLETGKQL 434 Query: 479 DDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTME----EGWISYDPYSIQYGDIHFY 534 D LYV + + +K R + S T+ + + GW Y P+ I+ + Sbjct: 435 DT-TRLYVAAFDLVRFNREKKRFVMEDSFTSQLDVVAVNKYMGW--YHPWPIEPENAV-- 489 Query: 535 NYADDCWNWKIFP-KARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRF 581 W++ P K ++SE+G ++ S E V+S Y +R Sbjct: 490 --------WEVIPDKPLIISEFGGEALYGQSGDENVASSWSEEYQARL 529 >6MVF-A nrPDB Length = 769 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 14/121 (11%) Query: 343 FKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANM------NTLRVWGGGIYE 396 F ING L+G QDK+ + DA + NT+R+ Sbjct: 287 FSINGEATPLRG-----VSRHQDKLYKGNALTVEDHYQDAQIIKELGANTIRL--AHYQH 339 Query: 397 QDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNN 456 +FY CDELG VW + F S ++ + V +E+ + + +HPSI+ W +N Sbjct: 340 SQDFYDACDELGFAVWAEIPFIS-VFKSGKDAHTHVMEEMKELIIQNYNHPSILFWGISN 398 Query: 457 E 457 E Sbjct: 399 E 399 >3CMG-A nrPDB Length = 667 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 45/166 (27%), Positives = 69/166 (41%), Gaps = 28/166 (16%) Query: 400 FYALCDELGIMVWQDFMFASALYPTEPGFL--ASVRKEVTYQ----VRRLKSHPSIIIWS 453 Y L D+ GI+ W + F + GF+ AS R+ Q +R+ +HPSI W Sbjct: 332 MYDLMDKHGIVTWAEIPFVGPGGYADKGFVDQASFRENGKQQLIELIRQHYNHPSICFWG 391 Query: 454 GNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKT 513 NE +K D+ V YVK + + ED +RP ++S +G Sbjct: 392 LFNE----------------LKEVGDNPVE-YVKELNALAKQEDPTRPTTSASNQDGNLN 434 Query: 514 MEEGWISYDPYSIQYGDI--HFYNYADDCWNWKIFPKARL-VSEYG 556 I+++ Y YG + D K P+ R+ +SEYG Sbjct: 435 FITENIAWNRYDGWYGSTPKTLATFLDRT--HKKHPELRIGISEYG 478 Score = 35.8 bits (81), Expect = 0.082, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 2/46 (4%) Query: 92 EWQKVKLI--FDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK 135 EW+ +L FDGV+++A++ N IG+ + + F+IT++VK Sbjct: 62 EWKGKRLFLRFDGVNSIADVFINRKHIGEHRGGYGAFIFEITDLVK 107 >6ED1-A nrPDB Length = 879 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%) Query: 395 YEQD-EFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWS 453 Y QD E Y CDELG++VW + + + F + ++ + + + +HPS+++W Sbjct: 359 YPQDPEIYRACDELGLIVWSEICVVNEVRKN-TAFAHNCKEMLKEMILQNYNHPSVVLWG 417 Query: 454 GNNE 457 NE Sbjct: 418 AMNE 421 >6ED2-A nrPDB Length = 631 Score = 39.3 bits (90), Expect = 0.008, Method: Compositional matrix adjust. Identities = 92/424 (21%), Positives = 153/424 (36%), Gaps = 94/424 (22%) Query: 65 FNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFT 124 F D R D W Y T F +P S W V L F V A + N V + + + F Sbjct: 81 FTDKASREYCGDFW-YETSFFVPAEWSGWDIV-LRFGSVTHRARVFVNGVEVAQHEGGFL 138 Query: 125 GYSFDITNVVKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKA 184 + +TN+V+ KL + + +E A T+ C + RK Sbjct: 139 PFDATVTNIVRYNQFNKLSVLANNELSETMLPAGTT---------------CTLADGRKI 183 Query: 185 QCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLP---VYDNASQAWNIEIKASFDV 241 + +D+ + GI + V +L LP V D +++ E A D Sbjct: 184 AAPY-FDF---YNYAGIHRPV-----------WLMALPKERVLDYSTRYRLTETGAEIDY 228 Query: 242 ASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGY 301 S + VTV + T+ + L+VK N + Sbjct: 229 TVSTNGPHPVTVELYDGTTRVA-----ESSGTTGTLVVK----------------NARLW 267 Query: 302 NMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPAD 361 N+ + D ++I + + V + I GI+ F +NG P++L+G Sbjct: 268 NVHAAYLYDLVIRIHEGSAVVDEYLDRI--GIRTFEIRHGRFLLNGSPVYLRG------- 318 Query: 362 SFQDKVTSD-RLQLLFQSVVDANMNTLRVWGGGIYE------QDEFYALCDELGIMVWQD 414 F +D R + L V + ++ G + +E Y + DE G ++ + Sbjct: 319 -FGRHEDADIRGRGLDLPTVKRDFELMKWIGANCFRTSHYPYAEEIYQMADEEGFLIIDE 377 Query: 415 -----FMFASALY----------------PTEPGFLASVRKEVTYQVRRLKSHPSIIIWS 453 FM ++A + T P L + + +T + R K+HPS+I WS Sbjct: 378 VPAVGFMQSTANFLAANQGNGRQQGFFEKETTPALLKNHKAALTDMIDRDKNHPSVIAWS 437 Query: 454 GNNE 457 NE Sbjct: 438 LLNE 441 >3HN3-A nrPDB Length = 613 Score = 38.5 bits (88), Expect = 0.012, Method: Compositional matrix adjust. Identities = 66/298 (22%), Positives = 103/298 (34%), Gaps = 52/298 (17%) Query: 286 AVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKI 345 V WWP + Y ++ L + + Y V GI+ F I Sbjct: 264 GVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPV-----GIRTVAVTKSQFLI 318 Query: 346 NGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYE------QDE 399 NG P + G N + + R + ++ + N LR G + +E Sbjct: 319 NGKPFYFHGVN-------KHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEE 371 Query: 400 FYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQV-----RRLKSHPSIIIWSG 454 +CD GI+V + + P F +V QV RR K+HP++++WS Sbjct: 372 VMQMCDRYGIVVIDE---CPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSV 428 Query: 455 NNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTM 514 NE L + Y+K + S D SRP S +N Sbjct: 429 ANEPASHL-----------------ESAGYYLKMVIAHTKSLDPSRPVTFVSNSNYAADK 471 Query: 515 EEGWI------SYDPYSIQYGDIHF--YNYADDCWNW-KIFPKARLVSEYGYQSWPSF 563 ++ SY + YG + A NW K + K + SEYG ++ F Sbjct: 472 GAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGF 529 >3FN9-A nrPDB Length = 692 Score = 37.7 bits (86), Expect = 0.020, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Query: 378 SVVDANMNTLRVWGGGIYEQ-DEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEV 436 +++D T+R Y+Q D Y+ CD LG+++W + + + E S +E+ Sbjct: 326 AIMDVGATTVRF---AHYQQSDYLYSRCDTLGLIIWAEIPCVNRVTGYETENAQSQLREL 382 Query: 437 TYQVRRLKSHPSIIIWSGNNE 457 +R+ +HPSI +W +NE Sbjct: 383 ---IRQSFNHPSIYVWGLHNE 400 >5Z1B-A nrPDB Length = 692 Score = 37.4 bits (85), Expect = 0.025, Method: Compositional matrix adjust. Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 5/114 (4%) Query: 343 FKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD-ANMNTLRVWGGGIYEQDEFY 401 F ING P + KG F + T D L + S++ + N+ R E Y Sbjct: 388 FLINGKPFYFKGFGKHEDSYFHGRGTDDVLNVKDVSLIHWLHANSFRTSHYPYAES--MY 445 Query: 402 ALCDELGIMVWQDF--MFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWS 453 LCD GI++ + + S L P R+ + + R K+HP I++WS Sbjct: 446 DLCDREGIVIIDEVPAVGMSWLQYANPLVAERHREAIRGMIARDKNHPCIVMWS 499 Score = 32.7 bits (73), Expect = 0.66, Method: Compositional matrix adjust. Identities = 23/95 (24%), Positives = 37/95 (38%), Gaps = 14/95 (14%) Query: 40 LPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLI 99 LP VPG + + L +Y W+ Y F +P L Q++ L Sbjct: 66 LPMAVPGSYNDQNDELNL---------RAHYGWV-----VYQRSFAVPSRLVAGQRMILR 111 Query: 100 FDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVV 134 FD A++ N +G F + FD+T+ + Sbjct: 112 FDAATHAADVYLNGQLLGSHFGGFLPFEFDVTSAL 146 >6MVG-A nrPDB Length = 777 Score = 37.4 bits (85), Expect = 0.029, Method: Compositional matrix adjust. Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 54/276 (19%) Query: 200 GIWKDVRIEAYNIAH--LDY-----LTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVT 252 G+++DV I A N +H LDY L P + + +E+ S + A + V Q+T Sbjct: 163 GMYRDVNIIAVNKSHFDLDYYGGNGLKVTPEVADKNAKIAVEVFLSGEKAGQQLVY-QIT 221 Query: 253 VAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGG 312 A L + I +Q V L + V W G + Y T+ DG Sbjct: 222 DAEGVLAAETKTGISDKQ----VNLEI-----TDVHLW--NGRKDPYLYTATVRLMEDGV 270 Query: 313 LKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRL 372 + + RT + P F+ N P L+G QD+ + Sbjct: 271 CIDSVSTRFGCRTFTI-------DPDKGFFLNGNSYP--LRG-----VSRHQDRAGNGNA 316 Query: 373 QLLFQSVVDANM------NTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPTE 425 L D ++ T+R+ Y+ + FY LCDE G+++W + + S Sbjct: 317 LLPEHHREDIDLICEMGATTIRL---AHYQHAQYFYDLCDEKGLVLWAEIPYISQ----- 368 Query: 426 PGFLASVRKEVTYQVRRL----KSHPSIIIWSGNNE 457 + + R+ Q++ L +HPSI++W +NE Sbjct: 369 --HMKNGRENTISQMKELIVQNYNHPSIVVWGLSNE 402 >6NCW-A nrPDB Length = 574 Score = 36.6 bits (83), Expect = 0.050, Method: Compositional matrix adjust. Identities = 109/479 (22%), Positives = 174/479 (36%), Gaps = 100/479 (20%) Query: 79 TYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVN 138 +YS EF+ N ++L F GV A +L + +G N +T FD+ V+KD+ Sbjct: 57 SYSREFEAKGN------IRLEFKGVSHTASVLVDGKPVGSHYNAYT--PFDV--VLKDIR 106 Query: 139 SLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPS 198 P + Q + I A SF D P+ Sbjct: 107 -----------------------------PGIHQ-----LEVI--ADNSFGPDSALHVPN 130 Query: 199 Q-----GIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTV 253 GI + V +E A+L ++ F P W + + SS + G V V Sbjct: 131 DYQSYGGISRGVVLEELGEAYLSWIHFTPFL--RKDGWYGKAEICVRNLSSGRLDGSVEV 188 Query: 254 AIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGL 313 I + + I L+ E+ ++ A E W P + Y +T + G Sbjct: 189 EIGK-NSFAVLPIVLEGEEEKSFSTEELPCPWA-ECWSPE---SPVLYLITAVLRTADGA 243 Query: 314 KIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG-SNWIPADSFQDKVTSDRL 372 + +V FR ++ + I +NG + +KG F + + Sbjct: 244 ADDIIDRVGFREIRTEGKDIL----------LNGRKLRIKGFCRHEDHPQFGCALPFSAM 293 Query: 373 QLLFQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPTE---PGF 428 Q + D N++R Y DE F LCDE GI+VW++ A L P F Sbjct: 294 QHDLMLIKDLGANSIRTVH---YPNDELFLDLCDEQGILVWEE-NHARGLSEENMRNPHF 349 Query: 429 LASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKN 488 + + +HPSI IW NE A + + Y + Y Sbjct: 350 KQQCGDCIREMITAHYNHPSIYIWG--ILNECASDTEY------GRECYSEQY------- 394 Query: 489 IRKIVLSEDKSRPFIASSPTNGMKT-MEEGW---ISYDPYSIQYGDIHFYNYADDCWNW 543 +++ S D RP SS + KT + G+ +SY+ Y Y D+ +Y D+ + W Sbjct: 395 --ELIKSLDPYRP--RSSASCRFKTDICLGYPEVVSYNIYPKWYHDVPVEDYLDELYQW 449 >6NCZ-A nrPDB Length = 610 Score = 36.6 bits (83), Expect = 0.052, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Query: 345 INGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALC 404 +NG P+FL+G + DS ++ R + + + + + +E L Sbjct: 305 LNGEPVFLRGIS-CHEDSVENGKGLTREERIENIRIAKELGCNFMRLAHYPHNEEMAKLA 363 Query: 405 DELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNEN 458 DELG+++W++ A+ + ++ + R + S+IIWS NEN Sbjct: 364 DELGLLLWEEIPVYWAIRFEREKTYEDAQNQLRELINRDWNRASVIIWSVGNEN 417 >5T99-A nrPDB Length = 822 Score = 36.2 bits (82), Expect = 0.072, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 4/63 (6%) Query: 399 EFYALCDELGIMVWQDFMFASALYPTEPG----FLASVRKEVTYQVRRLKSHPSIIIWSG 454 EF LCD +G++V + + G F +K++T + R ++HPS+I+WS Sbjct: 355 EFLDLCDRMGLVVLDEAFDEWTKAKVDNGYHLYFDEWSKKDLTSLIMRDRNHPSVIMWSI 414 Query: 455 NNE 457 NE Sbjct: 415 GNE 417 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%) Query: 91 SEWQK--VKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK--DVNSLKLQF 144 ++W+ V++ FDG + A++ N V +G+ +TG+ DIT +K + N L +Q Sbjct: 96 AQWKDKIVRIGFDGAMSEAKVWINGVKVGEHPYGYTGFEIDITKYLKIGEENVLAVQL 153 >5T9G-A nrPDB Length = 846 Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust. Identities = 79/408 (19%), Positives = 149/408 (36%), Gaps = 88/408 (21%) Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNS 139 YS F P N + +K ++FDGV +E N +G ++ + +DI++ + Sbjct: 89 YSKTFDTPDNFVD-KKCYIVFDGVYNNSEYWINGRKLGFHPYGYSPFFYDISDYLN---- 143 Query: 140 LKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQ 199 P Q+ V W + Sbjct: 144 -----------------------------PKGQENRISVRIDHSRYADSRW-----YTGS 169 Query: 200 GIWKDVRIEAYNIAHLD-YLTFL--PVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIP 256 GI+++ ++ + H+ + TF+ PV + NIE++ D + ++ G+V + Sbjct: 170 GIYRETQLIFTDKLHIPVWGTFVTTPVVSSERATVNIEVRVKNDYSGPRA--GEVRTSYF 227 Query: 257 QLKTQQTND------IELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALD 310 K ++ + IE +E +I + + +++ + W + IL +D Sbjct: 228 DSKNKKVGEKLTSFLIEAGKEMKINQSV-----EISNPSLWDVDSPSMYLAKSEIL--VD 280 Query: 311 GGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWI-PADSFQDKVTS 369 G + K R+++ + KG F +NG + +KG A + Sbjct: 281 GNVVDTKETPFGIRSIKF--DAKKG-------FFLNGKNMKIKGVCLHHDASMIGAALVE 331 Query: 370 DRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPG-- 427 D + Q++ D N +R+ D F LCDE+G +V ++F F YP + Sbjct: 332 DVWRRRLQTLKDGGCNAIRL--SHNPGADAFLELCDEMGFLVQEEF-FDEWDYPKDKRLN 388 Query: 428 ----------------FLASVRKEVTYQVRRLKSHPSIIIWSGNNENE 459 F +++ + R ++HP I WS NE E Sbjct: 389 MDEQSIDYITRGYCEYFQEWAERDLKNVMLRSRNHPCIFQWSIGNEIE 436 >6B6L-A nrPDB Length = 776 Score = 33.1 bits (74), Expect = 0.58, Method: Compositional matrix adjust. Identities = 63/282 (22%), Positives = 120/282 (42%), Gaps = 46/282 (16%) Query: 196 FPSQGIWKDVRIEAYNIAHLD-YLTFL--PVYDNASQAWNIEIKASFDVASSKSVGGQVT 252 + GI++ ++ N H + + TF+ PV + A E+ +A+++ V G+V Sbjct: 150 YTGSGIYRHTFLKITNPLHFETWGTFVTTPV----ATADKAEVHVQSVLANTEKVTGKV- 204 Query: 253 VAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDV--AVETWWPR--GHGNQTGYNMTILFA 308 I + + N+ + +++++V L K + +V A+E P+ N Y + Sbjct: 205 --ILETRIVDKNNHTVARKEQLVTLDNKEKTEVGHALEVLAPQLWSIDNPYLYQVVNRLL 262 Query: 309 LDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG------SNWIPADS 362 D + E+ + R + E F++NG + LKG + + A + Sbjct: 263 QDDKVIDEEYISIGIRNIAFSAEN---------GFQLNGKSMKLKGGCIHHDNGLLGAKA 313 Query: 363 FQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYAL---CDELGIMVWQD----F 415 F D+ +++LL A N LR + AL CD LG++V + + Sbjct: 314 F-DRAEERKIELLKA----AGFNALR-----LSHNPPSIALLNACDRLGMLVIDEAFDMW 363 Query: 416 MFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNE 457 + Y F ++++ V R ++HPS+I+WS NE Sbjct: 364 RYGHYQYDYAQYFDKLWKEDLHSMVARDRNHPSVIMWSIGNE 405 >4JKL-A nrPDB Length = 602 Score = 32.7 bits (73), Expect = 0.63, Method: Compositional matrix adjust. Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 28/136 (20%) Query: 343 FKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYE------ 396 F +N PI+ KG +D + R L ++ ++N L+ G + Sbjct: 283 FLLNRKPIYFKGFG-----KHEDTFINGRG--LNEAANLMDLNLLKDMGANSFRTSHYPY 335 Query: 397 QDEFYALCDELGIMV---------WQDFMFASALYPTEPGFLASVRKEVTYQ------VR 441 +E L D +G++V +Q+F + L P + G ++ + ++ V+ Sbjct: 336 SEEMMRLADRMGVLVIDEVPAVGLFQNFNASLDLSPKDNGTWNLMQTKAAHEQAIQELVK 395 Query: 442 RLKSHPSIIIWSGNNE 457 R K+HPS+++W NE Sbjct: 396 RDKNHPSVVMWVVANE 411 >5Z19-A nrPDB Length = 627 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 53/235 (22%), Positives = 80/235 (34%), Gaps = 60/235 (25%) Query: 301 YNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPA 360 Y + IL G+ E K+ RTV++ EG K +N P++LKG Sbjct: 278 YQIVILITDGNGVLDEYREKIGIRTVRI--EGTK--------ILLNDRPVYLKGFG---- 323 Query: 361 DSFQDKVTSDR------LQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQD 414 +D R ++ F+ + N N R +E+Y DE G ++ + Sbjct: 324 -KHEDFPILGRGFHWGIVKRDFECLKWTNANCFRT--SHYPYAEEWYQFADEEGFLIIDE 380 Query: 415 FMFASALYPTE-------------------PGFLASVRKEVTYQVRRLKSHPSIIIWSGN 455 + T P L S + + R K+HPS+I WS Sbjct: 381 VPAVGMMRSTRNFVAAGSGNYTYFFEALTVPELLKSHIADTEEMITRDKNHPSVIAWSLF 440 Query: 456 NENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSED-KSRPFIASSPTN 509 NE E I DY Y K + + D +SRP + N Sbjct: 441 NEPET-----------------ITDYAYEYFKEVFAAAETYDFQSRPMTGAFEKN 478 >4PU9-A nrPDB Length = 398 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 12/109 (11%) Query: 7 LILALFRAGCVVAGPSYSLSGSWR------VSNGNGSLELPATVPGYVHSALHQHGLIQD 60 +I+ + AG SY +SG V+ + LEL G +H +++HG+ Q Sbjct: 99 VIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQA 158 Query: 61 PYY------RFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGV 103 P + + W SL+ +T TEF+ +++ + GV Sbjct: 159 PLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGV 207 >5DMY-A nrPDB Length = 904 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 6/104 (5%) Query: 37 SLELPATVPGYVHSALHQHGLIQD-----PYYRFNDLNYRWISLDNWTYSTEFKIPFNLS 91 S + A P + SA Q L D Y + N+ ++ Y F I +L+ Sbjct: 50 SDSVQAQDPAFDDSAWQQVDLPHDYSITQKYSQSNEAESAYLPGGTGWYRKSFTIDRDLA 109 Query: 92 EWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK 135 +++ + FDGV A + FN V +G ++ +SFD+T K Sbjct: 110 G-KRIAINFDGVYMNATVWFNGVKLGTHPYGYSPFSFDLTGNAK 152 >5MMP-A nrPDB Length = 234 Score = 31.2 bits (69), Expect = 2.3, Method: Compositional matrix adjust. Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 12/109 (11%) Query: 7 LILALFRAGCVVAGPSYSLSGSWR------VSNGNGSLELPATVPGYVHSALHQHGLIQD 60 +I+ + AG SY +SG V+ + LEL G +H +++HG+ Q Sbjct: 107 VIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQA 166 Query: 61 PYY------RFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGV 103 P + + W SL+ +T TEF+ +++ + GV Sbjct: 167 PLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGV 215 >3VUP-A nrPDB Length = 351 Score = 30.4 bits (67), Expect = 3.8, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 9/79 (11%) Query: 342 YFKINGLPIFLKGSN--WIP-ADSFQD---KVTSDRLQLLFQSVVDANMNTLRVWGGGIY 395 +F +NG +FL G N W+ A F D + +R++ F+ + DA N++R+W I+ Sbjct: 8 HFVLNGQRVFLSGGNLPWMSYAYDFGDGQWQRNKNRIEPEFKKLHDAGGNSMRLW---IH 64 Query: 396 EQDEFYALCDELGIMVWQD 414 Q E ++ G + D Sbjct: 65 IQGETTPAFNDQGFVTGPD 83 >4CUC-A nrPDB Length = 849 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 3/51 (5%) Query: 84 FKIPFNLSEW---QKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDIT 131 ++ F L E + V+L FDGV +++ N +G N + +S+DIT Sbjct: 78 YRKTFKLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDIT 128 >1CT9-A nrPDB Length = 553 Score = 30.0 bits (66), Expect = 4.9, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 3/54 (5%) Query: 588 HEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSR 641 E NH ++HF + +G D +R D IY + I+ T YL SR Sbjct: 284 QEVANHLGTVHHEIHFTVQEGLDAIR---DVIYHIETYDVTTIRASTPMYLMSR 334 >2RCC-A nrPDB Length = 346 Score = 29.6 bits (65), Expect = 5.5, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 469 VNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEE 516 +NP DM+TYI ++ N R + L +K P I +P ++ E+ Sbjct: 276 INPEDMETYIS-----FIANKRAVQLGMEKPYPEIKHNPMKWIRAYED 318 >4YPJ-A nrPDB Length = 810 Score = 29.6 bits (65), Expect = 6.1, Method: Compositional matrix adjust. Identities = 39/181 (21%), Positives = 80/181 (44%), Gaps = 17/181 (9%) Query: 372 LQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFM--FASALYPTEPG-- 427 ++ Q + D +N +RV E ++LG+ + ++ +A + P + G Sbjct: 323 VERQMQIMKDMGVNAIRVTHNPA--SPELLEAANKLGLFIIEEAFDSWAQSKKPYDYGRF 380 Query: 428 FLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHV-NPRDMKTYIDDYVTLYV 486 F A ++ V R K+ P+II+WS NE+ + N V R++ ++ + + Sbjct: 381 FNAWAEHDIKEMVDRGKNEPAIIMWSIG--NEIYDTTNAAGVETARNLVGWVKE-----I 433 Query: 487 KNIRKIVLSEDKSR-PFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKI 545 R + EDK+R + +P N ++E + D + Y + ++ Y +WK+ Sbjct: 434 DTTRPTTIGEDKTRGDKVNVTPINSY--IKEIFNIVDVVGLNYSENNYDGYHKQNPSWKL 491 Query: 546 F 546 + Sbjct: 492 Y 492 >6D89-C nrPDB Length = 595 Score = 29.3 bits (64), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 1/54 (1%) Query: 88 FNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKD-VNSL 140 ++L +++ L F V+ A + N +G+ FT ++F+ITN++K+ NSL Sbjct: 109 YSLQPGKRLFLNFGAVNYEAIVWLNGKRLGRHIGGFTPFNFEITNLLKEGTNSL 162 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6DDT-A nrPDB 1173 0.0 2WBK-A nrPDB 926 0.0 6BYC-A nrPDB 891 0.0 5N6U-A nrPDB 861 0.0 4CVU-A nrPDB 698 0.0 3GM8-A nrPDB 301 1e-81 6D8K-A nrPDB 265 6e-71 6ETZ-A nrPDB 233 2e-61 6D1P-A nrPDB 230 2e-60 3DEC-A nrPDB 229 6e-60 6MVH-A nrPDB 212 6e-55 6D8G-A nrPDB 209 5e-54 6DXU-D nrPDB 185 5e-47 Sequences not found previously or not previously below threshold: 6MVG-A nrPDB 182 8e-46 6ED1-A nrPDB 175 6e-44 6NCW-A nrPDB 168 1e-41 5T9G-A nrPDB 158 6e-39 5T99-A nrPDB 155 6e-38 4YPJ-A nrPDB 155 1e-37 6MVF-A nrPDB 153 2e-37 6D89-C nrPDB 151 1e-36 6NCZ-A nrPDB 150 2e-36 3CMG-A nrPDB 150 3e-36 6B6L-A nrPDB 148 7e-36 5DMY-A nrPDB 146 4e-35 5Z1B-A nrPDB 141 2e-33 3FN9-A nrPDB 138 7e-33 6ED2-A nrPDB 138 9e-33 3HN3-A nrPDB 138 1e-32 6CXS-A nrPDB 138 1e-32 4CUC-A nrPDB 136 5e-32 5Z19-A nrPDB 126 4e-29 4JKL-A nrPDB 125 7e-29 5EUV-A nrPDB 125 1e-28 6ECA-A nrPDB 124 1e-28 5C70-A nrPDB 123 5e-28 3K4D-A nrPDB 120 3e-27 6BJW-A nrPDB 113 4e-25 4XZW-A nrPDB 45 2e-04 4UOQ-A nrPDB 40 0.006 4CT9-A nrPDB 38 0.017 4NRS-A nrPDB 38 0.018 5GSM-A nrPDB 36 0.069 5WH8-A nrPDB 36 0.096 3TTS-A nrPDB 35 0.12 2VRK-A nrPDB 35 0.21 3WH9-A nrPDB 34 0.34 4UCF-A nrPDB 34 0.39 3SMA-A nrPDB 33 0.66 3JUG-A nrPDB 33 0.67 5E9A-A nrPDB 33 0.72 3MAN-A nrPDB 32 1.2 5XTH-p nrPDB 32 1.3 4PSP-A nrPDB 32 1.3 2WHL-A nrPDB 32 1.3 6IJO-1 nrPDB 31 2.4 3WFL-A nrPDB 31 2.7 3VUP-A nrPDB 31 3.1 5BR7-A nrPDB 31 3.2 2CSX-A nrPDB 30 3.4 4AWE-A nrPDB 30 3.4 5OGZ-A nrPDB 30 4.9 6NMI-A nrPDB 30 7.0 5OF4-A nrPDB 30 7.0 5IY9-V nrPDB 30 7.0 4ERN-A nrPDB 30 7.0 >6DDT-A nrPDB Length = 868 Score = 1173 bits (3034), Expect = 0.0, Method: Composition-based stats. Identities = 858/858 (100%), Positives = 858/858 (100%) Query: 22 SYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYS 81 SYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYS Sbjct: 11 SYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYS 70 Query: 82 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK 141 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK Sbjct: 71 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK 130 Query: 142 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI 201 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI Sbjct: 131 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI 190 Query: 202 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ 261 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ Sbjct: 191 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ 250 Query: 262 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV 321 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV Sbjct: 251 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV 310 Query: 322 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD 381 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD Sbjct: 311 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD 370 Query: 382 ANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR 441 ANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR Sbjct: 371 ANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR 430 Query: 442 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRP 501 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRP Sbjct: 431 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRP 490 Query: 502 FIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP 561 FIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP Sbjct: 491 FIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP 550 Query: 562 SFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYL 621 SFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYL Sbjct: 551 SFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYL 610 Query: 622 TQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLH 681 TQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLH Sbjct: 611 TQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLH 670 Query: 682 YFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVV 741 YFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVV Sbjct: 671 YFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVV 730 Query: 742 KAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLE 801 KAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLE Sbjct: 731 KAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLE 790 Query: 802 ANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPT 861 ANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPT Sbjct: 791 ANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPT 850 Query: 862 SKSELQQAFSVTSLTDTY 879 SKSELQQAFSVTSLTDTY Sbjct: 851 SKSELQQAFSVTSLTDTY 868 >2WBK-A nrPDB Length = 847 Score = 926 bits (2392), Expect = 0.0, Method: Composition-based stats. Identities = 261/878 (29%), Positives = 420/878 (47%), Gaps = 73/878 (8%) Query: 25 LSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEF 84 L W S +PATVPG VH L H L+ +P+Y N+ +W+ ++W Y T F Sbjct: 11 LDTGWEFSQSGTEKWMPATVPGTVHQDLISHELLPNPFYGMNEKKIQWVENEDWEYRTSF 70 Query: 85 KIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVV-KDVNSLKLQ 143 + ++LIF+G+DT A++ N + K DNMF GY+ + +V+ K N L + Sbjct: 71 IVSEEQLNRDGIQLIFEGLDTYADVYLNGSLLLKADNMFVGYTLPVKSVLRKGENHLYIY 130 Query: 144 FRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVN-FIRKAQCSFSWDWGPSFPSQGIW 202 F S ++ Q A + P + E H++ F RKA S+ WDWG + G+W Sbjct: 131 FHSPIRQTLPQY-ASNGFNYPAD----NDHHEKHLSVFSRKAPYSYGWDWGIRMVTSGVW 185 Query: 203 KDVRIEAYNIAHLD--YLTFLPVYDNASQAWN-------IEIKASFDVASSKSVGGQVTV 253 + V + Y+IA + Y+ L + D ++ N + K +V + S+ G Sbjct: 186 RPVTLRFYDIATISDYYVRQLSLTDENARLSNELIVNQIVPQKIPAEVRVNVSLNGTTVT 245 Query: 254 AIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGL 313 + Q + LQ + L ++ V W P G G T Y+ + A + Sbjct: 246 EVKQ-------QVTLQPGINHITLPAEVTNPV---RWMPNGWGTPTLYDFSAQIACGDRI 295 Query: 314 KIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQ 373 E++ ++ RT++++ E K G SFYF++NG+P+F KG+N+IP D+ VT++R Q Sbjct: 296 VAEQSHRIGLRTIRVVNE--KDKDGESFYFEVNGIPMFAKGANYIPQDALLPNVTTERYQ 353 Query: 374 LLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVR 433 LF+ + +ANMN +R+WGGG YE + FY L DE GI+VWQDFMFA YP++P FL V Sbjct: 354 TLFRDMKEANMNMVRIWGGGTYENNLFYDLADENGILVWQDFMFACTPYPSDPTFLKRVE 413 Query: 434 KEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWF--HVNPRDMKTYIDDYVTLYVKNIRK 491 E Y +RRL++H S+ +W GNNE AL F P + + Y L+ + + Sbjct: 414 AEAVYNIRRLRNHASLAMWCGNNEILEALKYWGFEKKFTPEVYQGLMHGYDKLFRELLPS 473 Query: 492 IVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYS--IQYGDIHFYNYADDCWNWKIFPKA 549 V D R ++ SSP E W + D ++ + YG F + D Sbjct: 474 TVKEFDSDRFYVHSSPYLANWGRPESWGTGDSHNWGVWYGKKPFESLDTDL--------P 525 Query: 550 RLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGT 609 R +S++G+QS+P T+ ++ ED+ S Q GN + ++ + +P+ Sbjct: 526 RFMSQFGFQSFPEMKTIAAFAAPEDYQIESEVMNAHQKSSIGNSLIRTYMERDYIIPE-- 583 Query: 610 DPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWA 669 +F+D +Y+ V+Q Q ++ E + R+R + MG LYWQLND W SW+ Sbjct: 584 ----SFEDFVYVGLVLQGQGMRHGLEAHRRNRP-------YCMGTLYWQLNDSWPVVSWS 632 Query: 670 SLEYGGKWKMLHYFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWS-SP 728 S++Y G WK LHY A+R FAP+L + VY +SD D Q+T+ + Sbjct: 633 SIDYYGNWKALHYQAKRAFAPVLINPIQQNDSLSVYLISD-RLDTMEQMTLEMKVVDFDG 691 Query: 729 KPLCSLVN-SSIVVKAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFS---P 784 K L + S+ V A + +++ + L T E C SF K+ Sbjct: 692 KTLGKKIQVHSLEVPANTSKCVYRAKLDGWL------TPEDCRRSFLKLILKDKSGHQVA 745 Query: 785 TNYHFLSSLKDAKGLLEANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGF 844 + HF KD + L +++ + Q L +S +A ++++ R+SDN F Sbjct: 746 ESVHFFRKTKDLQ-LPPTSVSYQMKQTDGKCELTLFSSMLAKDIFIETPLQGARYSDNFF 804 Query: 845 LMI---RKKLSVLFYPWKPTSKSELQQAFSVTSLTDTY 879 ++ RKK+ + P K + ++ + +TY Sbjct: 805 DLLPGERKKVIIT----SPRIKKGEELPVNIKHIRETY 838 >6BYC-A nrPDB Length = 862 Score = 891 bits (2302), Expect = 0.0, Method: Composition-based stats. Identities = 271/902 (30%), Positives = 412/902 (45%), Gaps = 96/902 (10%) Query: 21 PSYSLSGSWRVSNGNGSL----------ELPATVPGYVHSALHQHGLIQDPYYRFNDLNY 70 + +L G WRV G LPA VPG V + L ++ DP+YR N+ Sbjct: 4 TAVTLDGGWRVRLVPGQEQGKTYPKAAAWLPAQVPGAVQTDLIAAKIVPDPFYRDNEGKI 63 Query: 71 RWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDI 130 +W L +W Y T F + + + V+L+FDG+DT AE+ N + DNMF + D Sbjct: 64 QWAGLSDWQYQTRFTVDAATLKREHVELVFDGLDTFAEVTLNGKQLLSADNMFRQWRVDA 123 Query: 131 TNVVK-DVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPV---EQKGECHVNFIRKAQC 186 +++K N L+++ S ++ + A Y +P E + ++RKA Sbjct: 124 KSLLKRGDNLLEVKLYSPIKKIQPWL-AKQPYALPGAYDSAFGDEPEARHSSTYVRKAPY 182 Query: 187 SFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKS 246 +F WDWGP + GIWKDVR+EA++ +D L +A A +++A D+ + +S Sbjct: 183 NFGWDWGPRMVNAGIWKDVRVEAWDAVRVDGLHIAQQRVDAHSA---QVQAQLDLQAGRS 239 Query: 247 VGGQVTVAI----PQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYN 302 QVT+ + Q Q T D + Q V L V+I + W+P G+G Q Y Sbjct: 240 GPVQVTLDVLGPDGQKVGQFTQDAVVDPGQNRVDLAVRIANP---KRWFPAGYGAQDRYT 296 Query: 303 MTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADS 362 G + R+V+L E K G S ING+PIF KG+N IP D+ Sbjct: 297 FVASVRDADGDSQQIKRVTGLRSVELRRE--KDRFGKSMEIVINGIPIFAKGANLIPLDA 354 Query: 363 FQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALY 422 F +VT +R++ Q DANMN LR+WGGG Y+ D FY + DELGIM+WQDFMF A+ Sbjct: 355 FPARVTHERMRSTLQDARDANMNMLRMWGGGHYQDDYFYDVADELGIMIWQDFMFGGAVP 414 Query: 423 PTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNW------FHVNPRDMKT 476 P + F + R+E QV+RL+ HPS+++W GNNE + V+P + Sbjct: 415 PYDVEFRENTRQEAIEQVKRLRDHPSLVLWCGNNEVQTGWENWGDRVKFKQSVDPEERTR 474 Query: 477 YIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNY 536 TL+ R++V + D P+ A+SP + GD+H++ Sbjct: 475 IERGMTTLFGTVFREVVATYDSDVPYWATSPGTDFDGAAD--------QTNDGDMHYWK- 525 Query: 537 ADDCWNWKIFP-------KARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHE 589 W P R +SEYG QS+P T+ + D + + R H + Sbjct: 526 ---VWGGPALPVTEYLNVTPRFMSEYGLQSFPDMRTVRAFAEPGD--MDPESPVMRVHQK 580 Query: 590 ----DGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIV 645 +GN +++ ++ F P + F+ +YL+Q+MQA+ I SR + Sbjct: 581 FDKGNGNKRLMLYIRREFGEP------KDFESFVYLSQLMQAEGINIAASHLRASRPQ-- 632 Query: 646 DGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFARRFFAPLLPVGFE-DEGVFYV 704 +MG+LYWQLND+W SW+S++Y G+WK LHY ARRF+AP + D+G V Sbjct: 633 -----SMGSLYWQLNDVWPGASWSSVDYYGRWKALHYHARRFYAPEMIAALRNDKGQTEV 687 Query: 705 YGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVVKAGEAVVLFQMPVSEL----LKR 760 VSD T LT R + ++ ++ K E + + + K+ Sbjct: 688 SLVSD----RTTPLTARW------RMRVMGMDGKVLSKREEKASVNALSSQHVGNFSDKQ 737 Query: 761 CRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLEANITVNISQKGNVFVFDLE 820 G + + D + F + K L A I G+ + L Sbjct: 738 LLGSADPKRTYAVFELLDGDTLLSREVVFFAPAKQL-ALPAAKIDSQWRADGDGYALTLT 796 Query: 821 TSAVAPFVWLDVGSIPGRFSDNGF-LMIRKKLSVLFYPWKPTSK---SELQQAFSVTSLT 876 + +A VWL G + SDN F L+ + L+V + TSK ++LQ A V L Sbjct: 797 SDTLAREVWLSFGDVDATLSDNAFDLLPGEPLTV-----RVTSKAALAQLQSALQVRDLA 851 Query: 877 DT 878 T Sbjct: 852 AT 853 >5N6U-A nrPDB Length = 836 Score = 861 bits (2223), Expect = 0.0, Method: Composition-based stats. Identities = 251/862 (29%), Positives = 425/862 (49%), Gaps = 77/862 (8%) Query: 24 SLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTE 83 L G W A VPG VH L ++GLI DP+ N+L +W+ ++W Y + Sbjct: 28 KLDGEWEFKAVKDKKWRKAKVPGCVHLDLMENGLIPDPFVGENELEVQWVEKEDWIYRKK 87 Query: 84 FKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVV-KDVNSLKL 142 F++ ++ + L F+G+DT +EI N IG+TDNMF + F++ +++ + N L++ Sbjct: 88 FQVGKEFLKYSSIYLEFEGIDTFSEIYLNGKKIGETDNMFIAWEFNVKDLLVEGENELEV 147 Query: 143 QFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVN--FIRKAQCSFSWDWGPSFPSQG 200 + S + E ++K + P + G + F RKAQ SF WDWGP + G Sbjct: 148 RLFSPSKVLEERAKNY----------PYKLHGGDYSPRVFGRKAQYSFGWDWGPRLATSG 197 Query: 201 IWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLK- 259 IWK V+++ +N A L ++PV S N +I D+ +S+ V I K Sbjct: 198 IWKSVKLKGWNKARL-LDVWVPV---RSLGENAQINIELDIELQESIPVDVAFRISHKKP 253 Query: 260 -TQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKA 318 +Q L + + +K+ + I+ + W+PRG+G Q Y + ++ + G ++K Sbjct: 254 VLEQRLRFTLPEGRVFLKIPLTIKNP---KLWFPRGYGEQNLYTLQLVLLDEKGEVLDKV 310 Query: 319 A-KVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQ 377 + R V+L + + + G SF FKIN +P+F KG+NWIPADSF ++ + +LL Sbjct: 311 EERFGIRKVELFTQ--EDNKGESFVFKINNIPVFAKGANWIPADSFLPRIKEEDYRLLLI 368 Query: 378 SVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVT 437 +A +N LRVWGGGIYE D FY LCDELGIMVWQDFMFA A YP + FL V+KE Sbjct: 369 RAKEAGVNMLRVWGGGIYENDIFYELCDELGIMVWQDFMFACAEYPDDENFLNDVQKEAE 428 Query: 438 YQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSED 497 + ++RL++HPSI++W GNN N W+ + I Y + + + D Sbjct: 429 FVIKRLRNHPSIVLWCGNNCNHWGYYAKWWGEREKFWGEEI------YSRVLPDVCARLD 482 Query: 498 KSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIH----FYNYADDCWNWKIFPKARLVS 553 +RP+ SSP G DP S + GD H ++ + D +N + R +S Sbjct: 483 LTRPYWPSSPYGGK----------DPNSQEVGDRHNWEVWHGWID--FNGYLKDNGRFIS 530 Query: 554 EYGYQSWPSFSTLEKV-SSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPL 612 E+G Q+ P T+ K +S++++ SR +G +++ + HFK+ + + Sbjct: 531 EFGMQAPPVAETIRKFITSEKEYYPQSREMEFHNKAREGTERIIRYIAGHFKITEDMN-- 588 Query: 613 RTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLE 672 + IYL+Q++Q +KT E + + K HT G+L WQ ND W SW+ ++ Sbjct: 589 ----EYIYLSQIIQGLALKTGIEHWR-------NNKFHTSGSLIWQWNDCWPVVSWSIID 637 Query: 673 YGGKWKMLHYFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLC 732 Y K K +YF +R F + G V+GV+D + + ++ + + + Sbjct: 638 YYKKLKPSYYFVKRAFRDIKVNIEPRNGKLLVFGVNDTLEKFYGKIEYAISTFRGKRRGK 697 Query: 733 SLVNSSIVVKAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSS 792 V+ I + A +V+L + + ++ K +E V Y +K+ N +F + Sbjct: 698 KEVD--IEIPANSSVILGEFNLEDVDK-----FKEFFYVQLY--NEKDELIDQNEYFFAP 748 Query: 793 LKDAKGLLEANITVNISQ-KGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLM-IRKK 850 + + L A + ++ + + N ++ ++E+ +A +W+ + + DN + + K Sbjct: 749 FRHLE-LPNAVVVYSVKEIEENSYLLNIESDFLA--LWVSLKLENAEWEDNFVNIYPKTK 805 Query: 851 LSVLFYPWKPTSKSELQQAFSV 872 S+ F P + E++ + Sbjct: 806 YSIRFK--APYTLKEVESKLKL 825 >4CVU-A nrPDB Length = 942 Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats. Identities = 260/964 (26%), Positives = 421/964 (43%), Gaps = 123/964 (12%) Query: 5 LLLILALFRAGCVVAGPSYSLSGS--------WRVSNGNGSLELPATVPGYVHSALHQHG 56 L L L++F AG VA + S W V+N G++ +P P H LH G Sbjct: 7 LSLSLSIF-AGAAVATTESTGKASIHDLALQKWTVTNEYGNITVPGKFPSQAHLDLHAAG 65 Query: 57 LIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVK--LIFDGVDTVAEILFNNV 114 +I + ND + RWI+ NWTY++ K LS+ + L+FDG+DT A + F + Sbjct: 66 VIGESNNGLNDFDLRWIAAQNWTYTS--KPISGLSKHSDIATWLVFDGLDTYATVKFCDH 123 Query: 115 TIGKTDNMFTGYSFDITNVVKDVNS---LKLQFRSAVQYAECQSKAHTSYRVPPECP-PV 170 +G DN F + +D+++ + S L + F S + + + P P Sbjct: 124 IVGTPDNQFRQWFYDVSSALASCKSDPVLSINFGSVPRIINAINASDEVQHWPASVVYPF 183 Query: 171 EQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRI-------EAYNI-AHLD------ 216 E ++RK Q F WDWGP+F G W+ RI E Y++ +D Sbjct: 184 EYPNR---QWVRKEQNDFGWDWGPAFSPVGPWQPGRIVQLSKGGELYSLNTDIDIFRKGQ 240 Query: 217 YLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVK 276 + F P + + W + AS D + ++V I ++ + + + + + Sbjct: 241 FNNFAP---DQTAPW--VVNASLDFLGTLPKHASMSVIITDASDSRSV-LYSGKLEGVTQ 294 Query: 277 LLVKIRKDVAVE-----TWWPRGHGNQTGYNMTILFALDGGLK--IEKAAKVYFRTVQLI 329 + + V ++ WWPR GNQ YN+T+ + G + +V FRT+ Sbjct: 295 SDMTVTGSVTIDAHKPKLWWPRDMGNQQLYNITVSVSSAGSKTPILVSQRRVGFRTILFS 354 Query: 330 EEGIKG-------SPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDA 382 I +PG +++F+ING + KG+N IP D+F +VTSDR+ LF SV Sbjct: 355 SGNITDAQIASGITPGNNWHFEINGHEFYAKGANLIPPDAFWPRVTSDRMNRLFDSVESQ 414 Query: 383 NMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRR 442 N N LRVW G Y D Y + DE G+++W +F F+ LYP F A+V E+TY VRR Sbjct: 415 NFNMLRVWSSGTYLPDWIYDIADERGVLLWSEFQFSDTLYPDSDDFKANVVGEITYNVRR 474 Query: 443 LKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPF 502 L H S+ W G NE E + +P + Y L++ + ++ + S + Sbjct: 475 LNHHASLACWMGGNEFENLMLPIAQGADPATYPYVLGQYENLFITTLFNVLAANSHSISY 534 Query: 503 IASSPTNGMKTMEEGWISYD---PYSIQ-----------YGDIHFYNYADDC-WNWKIFP 547 S N GW+ D P I YGD FYNY ++ +P Sbjct: 535 SPCSANN-------GWLEIDLDLPVPIVERYYNTTSGHIYGDTDFYNYDTSVSFDTSAYP 587 Query: 548 KARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHED-------------GNHQ 594 R +E+G+ S PS T ++ E+ ++NS + R HH G + Sbjct: 588 VGRFANEFGFISMPSIQTWQQAVDPEELSFNSTTVILRNHHYPAGGLTRNIHNSTLGQVE 647 Query: 595 MLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGA 654 M V+ ++ P TDP+ F + TQ+ QA K+E +FY R +G+ Sbjct: 648 MTLAVERYYPTPDKTDPVANFSSWCHATQLFQADMYKSEIQFYRRGSGLPE----RQLGS 703 Query: 655 LYWQLNDIWQAPSWASLEYGGKWKMLHYFARRFFAPLLPVGFED--EGVFYVYGVSDLHK 712 LYWQLNDIWQAP+WA LEY G+WK+L Y +RR + ++ F + ++ SDL + Sbjct: 704 LYWQLNDIWQAPTWAGLEYDGRWKVLPYVSRRTYEHVIASAFWNYTANELEIWVTSDLWE 763 Query: 713 DHHTQLTVRLHHWSSPKPLCSLVNSSIVVKAGEAVVLFQMPVSEL----LKRCRGCTRET 768 ++++ W K + ++ + + + +++ ++ + Sbjct: 764 PVAGEVSL---TWVDLK--GKPIANNAGMTKSTKFNVGAINTTQIITANIQSDLKIPDTS 818 Query: 769 CVVSFYFST----------DKELFSPTNYHFLS--SLKDAKGLLEANITVNISQKGNVFV 816 V T K + HFL + + +++ N S K Sbjct: 819 DAVLVIELTAHGKLPNAASSKTTTFTHHNHFLPVWPNQAKVSDPKLHLSYNKSTKK---- 874 Query: 817 FDLETSA-VAPFVWLDVGS-IPGRFSDNGFLM-IRKKLSVLFYPWKPTSKSELQQAFSVT 873 F +E +A V+ + WL + + G F DN F++ +K V F + T+ + + +V Sbjct: 875 FTVEATAGVSLYTWLTHPAGVLGFFDDNAFVLRPGEKKEVGFTLQQDTTGGKWTEQVTVE 934 Query: 874 SLTD 877 SL D Sbjct: 935 SLWD 938 >3GM8-A nrPDB Length = 801 Score = 301 bits (769), Expect = 1e-81, Method: Composition-based stats. Identities = 125/676 (18%), Positives = 218/676 (32%), Gaps = 142/676 (21%) Query: 19 AGPSYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNW 78 A S WR+ N + T + + Q G + W Sbjct: 24 ASSSSYNDSQWRILNIPHDWSIEGTYKQFENGTDWQSGFLP--------AGISW------ 69 Query: 79 TYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVN 138 Y F IP + +KV+++F+GV +E+ N +GK N + + +D+T Sbjct: 70 -YRKTFTIPSKW-KNKKVQILFEGVYLNSEVWINGHWLGKRPNGYISFVYDLT------- 120 Query: 139 SLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPS 198 P Q+G+ + + + W + Sbjct: 121 ------------------------------PYLQEGKNQIAVKVDHSKALTGRW---YTG 147 Query: 199 QGIWKDVRIEAYNIAHLDY--LTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIP 256 GI++ V + N H+ Y + F N A + + K + + + P Sbjct: 148 SGIYRPVYLLVSNPTHIPYSGIHFRSKLQNKQSA-TYTLSIEIETQEKKPIKVKTYLQAP 206 Query: 257 QLKTQQTND-IELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKI 315 T++ I + + L IRK + W P + Y + D + Sbjct: 207 NGSIADTSEKIFVSSADSLCFLSGSIRKPL---LWSPD---SPNVYTLICQLTRDNKILD 260 Query: 316 EKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG-SNWIPADSFQDKVTSDRLQL 374 E V FR QL + G F +NG + +KG + + V D L Sbjct: 261 ECRLPVGFR--QLEFNPVSG-------FLLNGKSLKIKGVCDHHTVGAVGAAVPDDLLHY 311 Query: 375 LFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFA----SALYPTEPGFLA 430 + + D N +R FY LCD +GIMV + + A F Sbjct: 312 RLKLLKDMGCNAIRTSHNPF--SPAFYNLCDTMGIMVLNEGLDGWNQPKAADDYGNYFDE 369 Query: 431 SVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIR 490 +K++T ++R ++HPSII+WS NE A + V+L+ Sbjct: 370 WWQKDMTDFIKRDRNHPSIIMWSIGNEVTGA------------TPEIQHNLVSLF----- 412 Query: 491 KIVLSEDKSRPFIA--SSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPK 548 D RP + PT GMKT F +N Sbjct: 413 ---HQLDPDRPVTQGGTDPTRGMKT--------------DYQKKFNYLDIIGFNGNGEEI 455 Query: 549 ARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQG 608 L E+ ++++P TL ++++ Y +R Q + F P Sbjct: 456 GEL--EHFHKNYP---TLCAIATEVPHTYQTRGVYRSQ---------TQWRRRDFPAPWE 501 Query: 609 TDPLRTFKDTIY----LTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQ 664 + ++ + + + + +C E++ Y +S + WQ + Sbjct: 502 KGNI-NWEQFKHRVFPIPDLTEKECFPEESD-YPYYQSSYDNASVRISARKSWQRTCSFP 559 Query: 665 AP----SWASLEYGGK 676 W S +Y G+ Sbjct: 560 WLMGEFRWGSFDYLGE 575 >6D8K-A nrPDB Length = 597 Score = 265 bits (677), Expect = 6e-71, Method: Composition-based stats. Identities = 96/523 (18%), Positives = 198/523 (37%), Gaps = 95/523 (18%) Query: 69 NYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSF 128 ++ W Y+ F ++ L F V + N IG + FT + Sbjct: 92 ELKYYEGTVW-YARHF--DAKRLTHKRQFLYFGAVSYRCRVYLNGAEIGSHEGGFTPFQI 148 Query: 129 DITNVV-KDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCS 187 ++T+++ + N + ++ + + A + Sbjct: 149 EVTDLLNEGENFIAIEVNN--------------------------------RRTKDAIPA 176 Query: 188 FSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSV 247 S+DW + GI +DV + +L+ F+ + + ++ S K Sbjct: 177 MSFDW---WNYGGITRDVLLVTTPQTYLED-YFIQLDKESPNRMIAKVALS-----DKKA 227 Query: 248 GGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILF 307 G ++TV+IP+LKT + D+ E + + + I+K +E W N Y + + Sbjct: 228 GEKITVSIPELKT--SIDMLTDAEGK-AETVFNIKK---LERW---SSENPKLYEVIVSS 278 Query: 308 ALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWI---PADSFQ 364 A D ++ FR + + G Y +NG P F+ ++ P + Sbjct: 279 AND-----RVEEQIGFRNITV--------KGTDIY--LNGKPTFMCSISFHEEIPQRMGR 323 Query: 365 DKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFY-ALCDELGIMVWQDFMFASALYP 423 +D LL + +N +R+ Y Q+E+ L +++G ++WQ+ + Sbjct: 324 AFSEADAAMLLNE-AKALGVNMIRL---AHYPQNEYTVRLAEKMGFILWQEIPVWQGIDF 379 Query: 424 TEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVT 483 T ++ ++ ++R ++ ++ W NE + + + N F + + +D Sbjct: 380 TNNNTRKKAQRMLSEMIKRDQNRCAVGYWGIANETQPSKARNEFLTSLLETGKQLDT-TR 438 Query: 484 LYVKNIRKIVLSEDKSRPFIASSPTNGMKTME----EGWISYDPYSIQYGDIHFYNYADD 539 LYV + + +K R + S T+ + + GW Y P+ I+ + Sbjct: 439 LYVAAFDLVRFNREKKRFVMEDSFTSQLDVVAVNKYMGW--YHPWPIEPENAV------- 489 Query: 540 CWNWKIFP-KARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRF 581 W++ P K ++SE+G ++ S E V+S Y +R Sbjct: 490 ---WEVIPDKPLIISEFGGEALYGQSGDENVASSWSEEYQARL 529 >6ETZ-A nrPDB Length = 989 Score = 233 bits (594), Expect = 2e-61, Method: Composition-based stats. Identities = 107/578 (18%), Positives = 190/578 (32%), Gaps = 146/578 (25%) Query: 20 GPSYSLSGSWRVSNGNGSLELP-------------ATVPGYVHSALHQHGL-----IQDP 61 P SL+G W+ GS P ++P +H HG +Q P Sbjct: 34 APRLSLNGEWQFRLSPGSRVAPDDGWQLGEALNGFESLPVPSSWPMHGHGAPAYTNVQFP 93 Query: 62 YYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDN 121 + + + N + L FDG+++ + N V +G T Sbjct: 94 F----AVEPPHVPEANPIGDHLVVFEAGPEFFPHALLRFDGIESAGTVWLNGVELGTTRG 149 Query: 122 MFTGYSFDITNVV-KDVNSLKLQF--RSAVQYAECQSKAHTSYRVPPECPPVEQKGECHV 178 + FD++ ++ + N+L ++ SA Y E Q Sbjct: 150 SRLAHEFDVSGILEQGENTLAVRVAQFSAASYVEDQDM---------------------- 187 Query: 179 NFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKAS 238 W W P GI++DV ++A A +D + YD+ + ++++AS Sbjct: 188 -----------W-WLP-----GIFRDVTLQARPAAGIDDVFVHAGYDHITGEGILKVEAS 230 Query: 239 FDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQ 298 + V +P+L + E++ AVE W Sbjct: 231 RGGQA-----IDAVVRVPELALELAAGTEVRV--------------PAVEPWS------- 264 Query: 299 TGYNMTILFALDGGLKIEKAA-KVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNW 357 + L+ E A ++ FR++ + + FK+NG I L+G N Sbjct: 265 --AEVPKLYEAAVSAAGESVALQIGFRSIAIEDA----------QFKVNGRRILLRGVNR 312 Query: 358 IPAD-SFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMV----- 411 V D ++ + + N+N +R +F AL D+LG V Sbjct: 313 HEHHPRLGRVVPRDVVEAELRLMKQHNINAIRT--SHYPPHPQFLALADQLGFYVVLECD 370 Query: 412 WQDFMFASALYP----TEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVA-----L 462 + F SA + +P + ++ + V R K+H S+++WS NE + Sbjct: 371 LETHGFESAGWAQNPSDDPQWEDALVDRMRRTVERDKNHASVVMWSLGNEAGTGRNLAAM 430 Query: 463 SVNWFHVNP-------RDMKTY-IDDYVTLYVKNIRKIV-----------LSEDKSR--- 500 S +P D + +D Y +Y + + D R Sbjct: 431 SRWTKDRDPSRPIHYEGDWSSEHVDVYSRMYASQAETALIGQGIEPALNDAALDARRRAM 490 Query: 501 PFIASSPTNGM----KTMEEGWISYDPYSIQYGDIHFY 534 PF+ + M M E ++ Y G + Sbjct: 491 PFVLCEYVHAMGNGPGGMSEYQALFEKYPRLMGGFVWE 528 >6D1P-A nrPDB Length = 814 Score = 230 bits (586), Expect = 2e-60, Method: Composition-based stats. Identities = 98/543 (18%), Positives = 189/543 (34%), Gaps = 83/543 (15%) Query: 29 WRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFN--DLNYRWISLDNWTYSTEFKI 86 W V P TVP L Q + + + D + + W Y T I Sbjct: 46 WEVMRPITGAGKPETVP------LWQKVTLPHCFNAEDAVDPDVNYYQGPGW-YRTMLNI 98 Query: 87 PFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKL---Q 143 + + L F+G E+ I + + DIT V+ L + Sbjct: 99 ENPYTN-GRTCLEFEGAGQKTEVYVYTTRIASHVGGYDEWKADITEAVEAFRRTPLCRER 157 Query: 144 FRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWK 203 F + A + + +P + G G+++ Sbjct: 158 FGGKIPIAIRCDNSRDTEMIPSDMSDFNLYG-------------------------GLYR 192 Query: 204 DVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQ-VTVAI--PQLKT 260 V + H + + D + +I I +F S K + ++ + P+ K Sbjct: 193 YVNLVYTPAVHFEQIRIEATTDEKGKQGSISIDIAFGGLSGKEKKAKEFSLRVFSPEGKE 252 Query: 261 QQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAK 320 + EL + I + +++ + W P + Y +D G + Sbjct: 253 VNSISSELTE---ISSYQISLKRP---QLWSPH---SPALYTCVAEL-IDNGDTLRTTQH 302 Query: 321 VYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADS-FQDKVTSDRLQLLFQSV 379 FR + E+G F +NG + L+G++ + +T + ++ Q + Sbjct: 303 FGFRHFRFEEKGP---------FYLNGERLLLRGTHRHEDHAGVGAALTEEMMRTEMQQI 353 Query: 380 VDANMNTLRVWGGGIYEQDEF-YALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTY 438 + N +R+ G Y+Q LCDELG++VW++ + + R+ +T Sbjct: 354 KEMGANFIRL---GHYQQSGIILRLCDELGLLVWEEIPWCRGGLG-GESYKNQARRMLTN 409 Query: 439 QVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDK 498 + + ++HPS+I+W NEN+ P D +T+ D + ++ + + D Sbjct: 410 MIEQHRNHPSVILWGLGNENDW----------PGDFQTFEKDSIRAFMGELHDLAHRLDP 459 Query: 499 SRPFIASSPTNGMKTMEEGWISYDP--YSIQYGDIHFYNYADDCWNWKIFPKARLVSEYG 556 +R S+ + ++ Y P ++ YG F NY + L +E+G Sbjct: 460 TR----STAIRRCEFCKDIVDVYSPTIWAGWYGRR-FRNYREMETAGINATTRFLHAEWG 514 Query: 557 YQS 559 S Sbjct: 515 GDS 517 >3DEC-A nrPDB Length = 1000 Score = 229 bits (582), Expect = 6e-60, Method: Composition-based stats. Identities = 109/594 (18%), Positives = 196/594 (32%), Gaps = 114/594 (19%) Query: 24 SLSGSWRVSNGNGSLELPA---------------TVPGYVHSALHQHGLIQDPYYRFNDL 68 SL+G W+ P VPG + + + Y F+D Sbjct: 46 SLNGQWKFHWVKNPDTRPKDFYKPSYYTGGWADIKVPGNWERQGYGTAIYVNETYEFDDK 105 Query: 69 N---------YRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKT 119 + + +Y FK+P +V L +GV + + N +G Sbjct: 106 MFNFKKNPPLVPYKENEVGSYRRTFKVPAGWEGR-RVVLCCEGVISFYYVWVNGEFLGYN 164 Query: 120 DNMFTGYSFDITNVV-KDVNS--LKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGEC 176 T +DIT+ + N+ L++ S+ Y ECQ Sbjct: 165 QGSKTAAEWDITDKLTDGENTIALEVYRWSSGAYLECQDM-------------------- 204 Query: 177 HVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNAS-QAWNIEI 235 W GI +DV + + ++ + + + E+ Sbjct: 205 -------------WR------LSGIERDVYLYSTPEQYIADYKVTSLLEKEHYKEGIFEL 245 Query: 236 KASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGH 295 + + +S + T+ KT +L+ ++ ++ V W Sbjct: 246 EVAVGGTASGTSSIAYTLKDASDKTVLEGSRKLESHGSGNLIVFDEQRLPDVRRW---NA 302 Query: 296 GNQTGYNMTILFALDGGLKIE-KAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG 354 + Y + + GG E KV FRT ++ + F ING+P+ +KG Sbjct: 303 EHPELYTLLLELKDAGGKVTEITGTKVGFRTSEI----------KNGRFCINGVPVLVKG 352 Query: 355 SNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEF-YALCDELGIMVWQ 413 N V+ + ++ + + N+NT+R Y + Y LCD G+ V Sbjct: 353 VNRHEHSQLGRTVSKELMEQDIRLMKQHNINTVR---NSHYPAHPYWYQLCDRYGLYVID 409 Query: 414 DFMFASALYPTEP-------GFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVAL---- 462 + S P +L + R K+HPS++IWS NE + Sbjct: 410 EANIESHGMGYGPASLAKDSTWLPAHIDRTRRMYERSKNHPSVVIWSLGNEAGNGINFER 469 Query: 463 SVNWFHVNPRDMKTY---------IDDYVTLY--VKNIRKIVLSEDKSRPFIASSPTNGM 511 + +W ++ D Y +Y V IR V+ +D RPFI + M Sbjct: 470 TYDWLKSVEKNRPVQYERAEENYNTDIYCRMYRSVDVIRNYVVRKDIYRPFILCEYLHAM 529 Query: 512 ----KTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWP 561 M+E W ++ + G +++ D + ++ + YG P Sbjct: 530 GNSCGGMKEYWEVFENEPMAQGGC-IWDWVDQSFR-EVDKDGKWYWTYGGDYGP 581 >6MVH-A nrPDB Length = 780 Score = 212 bits (539), Expect = 6e-55, Method: Composition-based stats. Identities = 94/501 (18%), Positives = 173/501 (34%), Gaps = 103/501 (20%) Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNS 139 Y+ + K L E L G + A++ N + D ++ + DIT + + + Sbjct: 79 YAKQLK-KSELPEADCYYLELRGANASADVYVNGKAVAHHDGGYSTWRVDITKELTEEEN 137 Query: 140 LKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQ 199 L + A Y + Sbjct: 138 LIV-------IAVENGVNDRVYPQNADFTFY----------------------------G 162 Query: 200 GIWKDVRIEAYNIAHLD-------YLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVT 252 G+++DV I A N +H D + P A + +E+ + A K V T Sbjct: 163 GLYRDVNIIAVNKSHFDLDYYGGPGIKVTPEIKGADASVEVEVFLTNAAADQKLV---YT 219 Query: 253 VAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGG 312 V + K + + + ++ + AV W +G + Y T AL G Sbjct: 220 VKDAEGKEVAKTETAAGETKAVLSIP-------AVHLW----NGKKDPYLYTAEVALVSG 268 Query: 313 LKIEKAAKVYF--RTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWI-----PADSFQD 365 + A F RT ++ E F +NG L+G + ++ Sbjct: 269 EEAVDAVSTRFGCRTFEIDPERG---------FILNGEEYPLRGVSRHQDRWGIGNALLP 319 Query: 366 KVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPT 424 + + + L + + T+R+ Y+ D+ FY LCDE G+++W + + S+ P Sbjct: 320 EHHREDIDL----ICELGATTIRL---AHYQHDQYFYDLCDERGLVIWAEIPYISSHMPN 372 Query: 425 EPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTL 484 S KE+ V + +HPSI++W +NE +A S + + Sbjct: 373 GRENTISQMKEL---VVQNYNHPSIVVWGLSNEITMAGSSDEDLLENH------------ 417 Query: 485 YVKNIRKIVLSEDKSR----PFIASSPTNGMKTMEEGWISYDPYSIQY-GDIHFYNYADD 539 + + +V D +R ++ + ISY+ Y Y GD+ D Sbjct: 418 --RILNDMVHEMDHTRLTTIAVVSMCDIHDPYIQIPDVISYNHYFGWYGGDVSMNGPWMD 475 Query: 540 CWNWKIFPKARLVSEYGYQSW 560 ++ + +SEYG ++ Sbjct: 476 NFHKEFPNIPLGMSEYGCEAL 496 >6D8G-A nrPDB Length = 886 Score = 209 bits (531), Expect = 5e-54, Method: Composition-based stats. Identities = 101/609 (16%), Positives = 201/609 (33%), Gaps = 92/609 (15%) Query: 2 HLHLLLILALFRAGCVVAGPSY-SLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQD 60 H +I++LF V A +++ SW+ G + + +++H + Sbjct: 14 HWMAAVIISLFVLPPVHAQRQTQTINDSWKFLKGECTAAADSAFDDSKWTSIH----LPH 69 Query: 61 PYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTD 120 + + W Y + +P + +++ L D A I N +G+ Sbjct: 70 TWNTDAYTEKDYYRGTGW-YRRQLTLPQGW-KEKQIILRLDAAGKSATIYINGKNVGEHA 127 Query: 121 NMFTGYSFDITNVVKDV--NSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHV 178 +T SF+IT + N+L + +A Q S T + Sbjct: 128 GGYTACSFNITPFLSFDTPNTLAVCVDNARQDIAPISGDFTFFG---------------- 171 Query: 179 NFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHL-------DYLTF-LPVYDNASQA 230 GI++DV + A H D L P Sbjct: 172 ---------------------GIYRDVWLTAVPNQHFNLTNHGSDGLFISTPQVSEEQAT 210 Query: 231 WNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQ-QEQRIVKLLVKIRKDVAVET 289 +I + D ++ T+ P QT +Q + + + E Sbjct: 211 LSIRGEVKNDAPEKATLELTHTIYRPDGTLLQTLKKNIQLKAGETYAFSNEATPVLKPEL 270 Query: 290 WWPRGHGNQTGYNMTILFALDGGLKI--EKAAKVYFRTVQLIEEGIKGSPGLSFYFKING 347 W P Y + + + FR + F +NG Sbjct: 271 WTP---ETPRLYRVETTLRNRKTKTLLDQSNHYTAFRWFRFD---------GDEGFFLNG 318 Query: 348 LPIFLKGSNWIP-ADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDE 406 P L+G +T++ + F + + N +R+ + D +CD+ Sbjct: 319 KPYKLRGICRHQDQKPIGPALTAEMHRRDFLLMKEMGANFIRI--SHYPQADALLEMCDK 376 Query: 407 LGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNW 466 LG++ W++ + P PG+ + + + +R+ +HPSII W NE+ L Sbjct: 377 LGMLAWEEIPIID-IVPNTPGYGDNCERNLREMIRQHYNHPSIITW--GYMNEILLVTQR 433 Query: 467 FHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWIS----YD 522 + ++K ++ + L + +++ ED +R I++ +G + E +S Sbjct: 434 KYKTEAELKPVLERTLAL-ANRLERVLKEEDSTR--ISTMAFHGSNSYNETGLSKITDIV 490 Query: 523 PYSIQYGDIHFYNYADDCWNWKIFPK-------ARLVSEYGYQSWPSFSTLEKVSSQEDW 575 +++ G +Y + + + +VSEYG S +L + Sbjct: 491 GWNLYQG---WYGGDLTGFEKFLAQQHQNHPTHPMIVSEYGAGSDKRLHSLHPRAFDFSI 547 Query: 576 AYNSRFSLH 584 Y ++ H Sbjct: 548 EYQQKYLEH 556 >6DXU-D nrPDB Length = 830 Score = 185 bits (470), Expect = 5e-47, Method: Composition-based stats. Identities = 82/503 (16%), Positives = 169/503 (33%), Gaps = 72/503 (14%) Query: 12 FRAGCVV-AGPSYSLSGSWRVSNGN-GSLE---LPATVPGYVHSALHQHGLIQDPYYRFN 66 F++ V A L+ +W G+ G + PA + Q + + + Sbjct: 19 FQSNAKVPAMNKIRLTNNWEYLKGDLGGIWEAVRPAAPGSSEAVPIWQPVTLPHCFNAED 78 Query: 67 --DLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFT 124 D + + W Y T I ++ L FDG ++ +G + Sbjct: 79 AVDPDVNYYEGPGW-YKTLLAIDNPYRN-GRIVLDFDGAGQKTDVYVYTTHVGSHVGGYD 136 Query: 125 GYSFDITNVVK---DVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFI 181 ++ DIT+ VK + C + +P + G Sbjct: 137 SWNVDITDAVKAFLGSKDAERFKGKVPLSIRC-DNSRDLEMIPSDLADFNIYG------- 188 Query: 182 RKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASF-D 240 G+++ + + + + + + +++K SF + Sbjct: 189 ------------------GLYRYLNLVYLPEVSFEQIHLESSLSSNLKEGILKVKTSFYN 230 Query: 241 VASSKSVGGQVTVAIPQLKTQQTNDIE-LQQEQRIVKLLVKIRKDVAVETWWPRGHGNQT 299 + V+V K + +E + + +KI+ V W Sbjct: 231 PEDIRKADVTVSVYDVDRKPVFSKTLEGILPLGDQLLAKMKIKNPV---LW---DVDVPQ 284 Query: 300 GYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIP 359 Y + + FR + ++G F +NG + L+G++ Sbjct: 285 LYTCELTVKTPD-QTFTTEERFGFRHTEFKDKGP---------FFLNGKRLLLRGTHRHE 334 Query: 360 ADSFQD-KVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEF-YALCDELGIMVWQDFMF 417 + +T D ++ + + D +N +R+ G Y+Q E LCDELGI+VW++ + Sbjct: 335 DHAGVAQAMTEDMMRREMRMMKDMGVNFIRL---GHYQQSEIILDLCDELGILVWEEIPW 391 Query: 418 ASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTY 477 + + R+ + + + +HP++IIW NEN+ P D T+ Sbjct: 392 CRGGLGGDV-YKKQARRMLANMIVQHHNHPAVIIWGLGNENDW----------PNDFNTF 440 Query: 478 IDDYVTLYVKNIRKIVLSEDKSR 500 + ++K + + D +R Sbjct: 441 DKSAIRAFMKELHDMAHRLDDTR 463 >6MVG-A nrPDB Length = 777 Score = 182 bits (460), Expect = 8e-46, Method: Composition-based stats. Identities = 86/493 (17%), Positives = 167/493 (33%), Gaps = 102/493 (20%) Query: 88 FNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQFRSA 147 L E ++ L F GV+ A++ N + D ++ + ++T+ + D +L + Sbjct: 86 EELPEGEQYYLEFLGVNASADVYVNGNHLDHHDGGYSTWRVNMTDALTDGKNLIV----- 140 Query: 148 VQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRI 207 A S Y + G+++DV I Sbjct: 141 --VAVDNSANDRVYPQKADFTFY----------------------------GGMYRDVNI 170 Query: 208 EAYNIAHLD-------YLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKT 260 A N +H D L P + + +E+ S + G Q+ I + Sbjct: 171 IAVNKSHFDLDYYGGNGLKVTPEVADKNAKIAVEVFLS-----GEKAGQQLVYQITDAEG 225 Query: 261 QQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAK 320 + + + V L + V W G + Y T+ DG + + Sbjct: 226 VLAAETKTGISDKQVNLEIT-----DVHLW--NGRKDPYLYTATVRLMEDGVCIDSVSTR 278 Query: 321 VYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPA-----DSFQDKVTSDRLQLL 375 RT + + F +NG L+G + ++ + + + L Sbjct: 279 FGCRTFTIDPDKG---------FFLNGNSYPLRGVSRHQDRAGNGNALLPEHHREDIDL- 328 Query: 376 FQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPTEPGFLASVRK 434 + + T+R+ Y+ + FY LCDE G+++W + + S S K Sbjct: 329 ---ICEMGATTIRL---AHYQHAQYFYDLCDEKGLVLWAEIPYISQHMKNGRENTISQMK 382 Query: 435 EVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVL 494 E+ + + +HPSI++W +NE ++ + D ++ + + Sbjct: 383 EL---IVQNYNHPSIVVWGLSNEITMSGEAD------------EDLMENHHI--LNDLAH 425 Query: 495 SEDKSRPFIASSPTNGMKTMEEGWI------SYDPYSIQY-GDIHFYNYADDCWNWKIFP 547 D +R + + M M +I SY+ Y Y GD D ++ + Sbjct: 426 EMDPTR--LTTMAVVSMCDMHNPYIQIPDVVSYNHYFGWYGGDTSMNGPWMDEFHKEFPK 483 Query: 548 KARLVSEYGYQSW 560 +SEYG ++ Sbjct: 484 IPIGMSEYGCEAL 496 >6ED1-A nrPDB Length = 879 Score = 175 bits (444), Expect = 6e-44, Method: Composition-based stats. Identities = 86/564 (15%), Positives = 177/564 (31%), Gaps = 100/564 (17%) Query: 20 GPSYSLSGSWRVSNGNGSL----------ELPATVPGYVHSALHQHGLIQDPYYRFNDLN 69 S++ SW+ N + +P + G + D + Sbjct: 24 ASEISITDSWKYKAENDERFSSMDWNDSDWVTVDLPHTWN-----AGDVIDEQRGYRRG- 77 Query: 70 YRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFD 129 W Y + IP + +K+ L FDGV + A++ N + +T + D Sbjct: 78 ISW-------YRKKLFIPSE-ARDKKITLRFDGVASKADVYLNGKLLKTHLGAYTAFGVD 129 Query: 130 ITNV--VKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCS 187 IT++ V N L ++ + + +PP G Sbjct: 130 ITDICEVGKENLLAVKV---------DNSSSLGEILPPVSGDFSIFG------------- 167 Query: 188 FSWDWGPSFPSQGIWKDVRIEAYNIAH--------LDYLTFLPVYDNASQAWNIEIKASF 239 GI++ V ++ H + P + + I Sbjct: 168 ------------GIYRRVFLQWTEKVHFVTEPYAAVPVRIQTPEVSVSEASMQIVAFLKN 215 Query: 240 DVASSKSVGGQVTVAIPQLKTQQTNDIELQ-QEQRIVKLLVKIRKDVAVETWWPRGHGNQ 298 D +K V V + + + ++L+ R + + + W P Sbjct: 216 DFTDTKHVHVNVFLCDEMNRIVKEKQLKLKLIPGRKYPISTSVGRIENPHLWSP---ELP 272 Query: 299 TGYNMTILFALDGGLKI--EKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSN 356 Y + + ++ E + V FR + + G F +NG + L+G+ Sbjct: 273 YLYTVKVQVCDAKNGEMYQEVISPVGFRWFSVDKTG----------FYLNGKYLKLRGAA 322 Query: 357 WIPADS-FQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDF 415 + + + + + + + N +R+ + E Y CDELG++VW + Sbjct: 323 RHQDYAGLGTAIPVEMNRRDMRLLKEMGANFVRI--SHYPQDPEIYRACDELGLIVWSEI 380 Query: 416 MFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNEN-EVALSVNWFHVNPRDM 474 + + F + ++ + + + +HPS+++W NE + + Sbjct: 381 CVVNEVRKNT-AFAHNCKEMLKEMILQNYNHPSVVLWGAMNELWDYHKQAIALARELEAL 439 Query: 475 KTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTME--EGWISYDPYSIQYGDIH 532 K +D Y L + ++ + + + E W D +I Sbjct: 440 KKELDPY-RLSCVAFHAFTWEKPYTQSSKEMFSISDVNGVNVYESWYQGDSATIAP---- 494 Query: 533 FYNYADDCWNWKIFPKARLVSEYG 556 D + K R +SE+G Sbjct: 495 ----MFDKFCSYSTAKPRFLSEFG 514 >6NCW-A nrPDB Length = 574 Score = 168 bits (424), Expect = 1e-41, Method: Composition-based stats. Identities = 94/514 (18%), Positives = 169/514 (32%), Gaps = 87/514 (16%) Query: 79 TYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVN 138 +Y + ++L F GV A +L + +G N +T + + ++ ++ Sbjct: 51 SYRGQASYSREFEAKGNIRLEFKGVSHTASVLVDGKPVGSHYNAYTPFDVVLKDIRPGIH 110 Query: 139 SLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPS 198 L++ A+ ++ VP + Sbjct: 111 QLEV-------IADNSFGPDSALHVPNDYQSY---------------------------- 135 Query: 199 QGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQL 258 GI + V +E A+L ++ F P W + + SS + G V V I Sbjct: 136 GGISRGVVLEELGEAYLSWIHFTPFL--RKDGWYGKAEICVRNLSSGRLDGSVEVEI--G 191 Query: 259 KTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKA 318 K + + + + E W P + Y +T + G + Sbjct: 192 KNSFAVLPIVLEGEEEKSFSTEELPCPWAECWSP---ESPVLYLITAVLRTADGAADDII 248 Query: 319 AKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPAD-SFQDKVTSDRLQLLFQ 377 +V FR ++ + I +NG + +KG F + +Q Sbjct: 249 DRVGFREIRTEGKDI----------LLNGRKLRIKGFCRHEDHPQFGCALPFSAMQHDLM 298 Query: 378 SVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPTE---PGFLASVR 433 + D N++R Y DE F LCDE GI+VW++ A L P F Sbjct: 299 LIKDLGANSIRTV---HYPNDELFLDLCDEQGILVWEE-NHARGLSEENMRNPHFKQQCG 354 Query: 434 KEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIV 493 + + +HPSI IW NE + + +++ Sbjct: 355 DCIREMITAHYNHPSIYIWGILNECASDTEYGRECYSEQ-----------------YELI 397 Query: 494 LSEDKSRPFIASSPTNGMK---TMEEGWISYDPYSIQYGDIHFYNYADDCWNW-----KI 545 S D RP ++S E +SY+ Y Y D+ +Y D+ + W + Sbjct: 398 KSLDPYRPRSSASCRFKTDICLGYPEV-VSYNIYPKWYHDVPVEDYLDELYQWIQNESEG 456 Query: 546 FPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNS 579 K L++E G + + T V E++ + Sbjct: 457 TGKPFLITEIGAGAIYGYRTPAHVKWSEEYQVQA 490 >5T9G-A nrPDB Length = 846 Score = 158 bits (400), Expect = 6e-39, Method: Composition-based stats. Identities = 74/457 (16%), Positives = 143/457 (31%), Gaps = 84/457 (18%) Query: 29 WRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPF 88 + N N S +P L + F W YS F P Sbjct: 46 YSFVNYNPSSWKTVNLPHDWSVDL-PFESTAEGCTGFLKGGIGW-------YSKTFDTPD 97 Query: 89 NLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQFRSAV 148 N + +K ++FDGV +E N +G ++ + +DI++ + Sbjct: 98 NFVD-KKCYIVFDGVYNNSEYWINGRKLGFHPYGYSPFFYDISDYL-------------- 142 Query: 149 QYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIE 208 P Q+ ++ W + GI+++ ++ Sbjct: 143 -------------------NPKGQENR--ISVRIDHSRYADSRW---YTGSGIYRETQLI 178 Query: 209 AYNIAHLDY---LTFLPVYDNASQAWNIEIKASFDVASSKSVGGQV-TVAIPQLKTQQTN 264 + H+ PV + NIE++ D + ++ + K + Sbjct: 179 FTDKLHIPVWGTFVTTPVVSSERATVNIEVRVKNDYSGPRAGEVRTSYFDSKNKKVGEKL 238 Query: 265 DIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFR 324 L + + +K+ + W + + Y +DG + K R Sbjct: 239 TSFLIEAGKEMKINQSVEIS-NPSLW---DVDSPSMYLAKSEILVDGNVVDTKETPFGIR 294 Query: 325 TVQLIEEGIKGSPGLSFYFKINGLPIFLKG-SNWIPADSFQDKVTSDRLQLLFQSVVDAN 383 +++ + F +NG + +KG A + D + Q++ D Sbjct: 295 SIKFDAKKG---------FFLNGKNMKIKGVCLHHDASMIGAALVEDVWRRRLQTLKDGG 345 Query: 384 MNTLRVWGGGIYEQDEFYALCDELGIMVWQDF-------------MFASALY----PTEP 426 N +R+ D F LCDE+G +V ++F M ++ Sbjct: 346 CNAIRLSHN--PGADAFLELCDEMGFLVQEEFFDEWDYPKDKRLNMDEQSIDYITRGYCE 403 Query: 427 GFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALS 463 F +++ + R ++HP I WS NE E Sbjct: 404 YFQEWAERDLKNVMLRSRNHPCIFQWSIGNEIEWTYK 440 >5T99-A nrPDB Length = 822 Score = 155 bits (392), Expect = 6e-38, Method: Composition-based stats. Identities = 102/625 (16%), Positives = 184/625 (29%), Gaps = 124/625 (19%) Query: 78 WTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK-- 135 W Y F I + + V++ FDG + A++ N V +G+ +TG+ DIT +K Sbjct: 87 W-YRKTF-IGDAQWKDKIVRIGFDGAMSEAKVWINGVKVGEHPYGYTGFEIDITKYLKIG 144 Query: 136 DVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPS 195 + N L +Q S W Sbjct: 145 EENVLAVQL---------------------------------------TPRDLSSRW--- 162 Query: 196 FPSQGIWKDVRIEAYNIAHLD----YLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQV 251 +P GI+++V + N ++ Y+T P + IE + + Sbjct: 163 YPGAGIYRNVWLRVDNKVYIPEHGVYVT-TPTVTKSKAVVQIETTVKNATFGNGKFNIRH 221 Query: 252 TVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDG 311 ++ Q +T + ++ + + W G N Y + Sbjct: 222 SIINAQGETVAILNDNVEVAAGEQGKTLAYINMLNPNIW---GQKNPYMYKLKTEIYDGK 278 Query: 312 GLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG-SNWIPADSFQDKVTSD 370 L R + ++G F +NG I G V Sbjct: 279 DLTDTYFTDFGIRKICFTKDG----------FFLNGEKIRFNGVCLHHDNGPMGAAVNVR 328 Query: 371 RLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDF--MFASALYPTE--P 426 + Q + + +N +R EF LCD +G++V + + A Sbjct: 329 ADERKLQIMKEMGVNAIRTSHN--PPSPEFLDLCDRMGLVVLDEAFDEWTKAKVDNGYHL 386 Query: 427 GFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYV 486 F +K++T + R ++HPS+I+WS NE Sbjct: 387 YFDEWSKKDLTSLIMRDRNHPSVIMWSIGNEILEQSDKKKGFTV---------------A 431 Query: 487 KNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFY--NYADDCWNWK 544 K + I D +RP T G + + + +++ YA+ + Sbjct: 432 KYLADICRELDPTRP-----STCGFNYYPAPFDNNMAQQVDIAGMNYKPGKYAEVQRLYP 486 Query: 545 IFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFK 604 P T SS+ + ++ ++G +Q+ Sbjct: 487 DLP------------LYGSETSSCTSSRGVYHLPIE-----KYEKNGTNQVTSY---DLI 526 Query: 605 LPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRS-EIVDGKGHTMGALYWQLNDIW 663 P+ P + + I T ++ D H YW ND W Sbjct: 527 GPKWAYPPDIEFHFQEMNPRFMGEFIWTGFDYLGEPTPYGGRDNSTHG----YW--NDDW 580 Query: 664 QAPSWASLEYGGKWKMLHYFARRFF 688 + S Y G + RF+ Sbjct: 581 PSRS----SYFGAVDLCGLPKDRFY 601 >4YPJ-A nrPDB Length = 810 Score = 155 bits (390), Expect = 1e-37, Method: Composition-based stats. Identities = 93/571 (16%), Positives = 185/571 (32%), Gaps = 95/571 (16%) Query: 36 GSLELPATVPG--YVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEW 93 S +P + +++ L + D W Y F IP + Sbjct: 36 DSSWRKLNLPHDWSIELDFNKNSLATHEG-GYLDGGIGW-------YRKTFTIP-ESMKG 86 Query: 94 QKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQFRSAVQYAEC 153 +++ L FDGV + N +G + +S+DI++ + Sbjct: 87 KRISLDFDGVYMNSTTYLNGEVLGTYPFGYNAFSYDISDKLYKD---------------- 130 Query: 154 QSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIA 213 G +V ++ S W + GI+++V + + Sbjct: 131 --------------------GRANVLVVKVNNTQPSSRW---YSGSGIYRNVYLTVTDPI 167 Query: 214 HLD-YLTFLP------VYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDI 266 H+ Y TF+ NI+ K S D A +K V + T+ T QT + Sbjct: 168 HVARYGTFVTTPNLEKSIKEDRADVNIKTKISNDAAEAKQVKIKSTIYDGAGNTVQTVET 227 Query: 267 ELQQEQRIVKLLVKIRKDV-AVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRT 325 E + + + + W YN+ + G K R Sbjct: 228 EEKTAAAGTVTPFEQNTVIKQPKLWSID---KPYRYNLVTEVIVGGQTVDTYETKFGVRY 284 Query: 326 VQLIEEGIKGSPGLSFYFKINGLPIFLKGSN-WIPADSFQDKVTSDRLQLLFQSVVDANM 384 + E F +NG + L G + + + ++ Q + D + Sbjct: 285 FKFDENEG---------FSLNGEYMKLHGVSMHHDLGALGAATNARGVERQMQIMKDMGV 335 Query: 385 NTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFA----SALYPTEPGFLASVRKEVTYQV 440 N +RV E ++LG+ + ++ + Y F A ++ V Sbjct: 336 NAIRVTHN--PASPELLEAANKLGLFIIEEAFDSWAQSKKPYDYGRFFNAWAEHDIKEMV 393 Query: 441 RRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSR 500 R K+ P+II+WS NE + + + + R + EDK+R Sbjct: 394 DRGKNEPAIIMWSIGNEIYDTTNAAGVETARNLVGWVKE------IDTTRPTTIGEDKTR 447 Query: 501 -PFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQS 559 + +P N ++E + D + Y + ++ Y +WK+ YG ++ Sbjct: 448 GDKVNVTPINSY--IKEIFNIVDVVGLNYSENNYDGYHKQNPSWKL---------YGSET 496 Query: 560 WPSFSTLEKVSSQEDWAYNSRFSLHRQHHED 590 + + + + +++++ +Q D Sbjct: 497 SSATRSRGVYTHPYQYNQSTKYADLQQSSYD 527 >6MVF-A nrPDB Length = 769 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 85/534 (15%), Positives = 164/534 (30%), Gaps = 93/534 (17%) Query: 79 TYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK-DV 137 YS FK P +V + A + N + F+ + DIT++ + Sbjct: 72 VYSRTFKKPVQPLTGGRVYVEVLAAALDATVKVNGTVATTHEGGFSIFRADITDLCRDGD 131 Query: 138 NSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFP 197 N L ++ S T P Sbjct: 132 NELTIEV----------SNEDTPSMYPASADFTFY------------------------- 156 Query: 198 SQGIWKDVRIEAYNIAHLDYLTF------LPVYDNASQAWNIEIKASFDVASSKSVGGQV 251 G+++ V + + AH D + + A EIK SF S Sbjct: 157 -GGLYRGVNLISVPNAHFDLDYYGGPGIMVTPKPTADGGATFEIK-SFVTNPDDSFTVMY 214 Query: 252 TVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDG 311 ++ P + ++ + I A E W Y + + Sbjct: 215 SIEDPYGCEVASA---VRPSDN---TAISIYVPDA-ELW---SMDEPNLYTVVARLQRNN 264 Query: 312 GLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSF-QDKVTSD 370 E A V R+ + +G F ING L+G + + + +T + Sbjct: 265 EAFDEIYANVGVRSYTVTPDGG---------FSINGEATPLRGVSRHQDKLYKGNALTVE 315 Query: 371 RLQLLFQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPTEPGFL 429 Q + + NT+R+ Y+ + FY CDELG VW + F S ++ + Sbjct: 316 DHYQDAQIIKELGANTIRL---AHYQHSQDFYDACDELGFAVWAEIPFIS-VFKSGKDAH 371 Query: 430 ASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNI 489 V +E+ + + +HPSI+ W +NE + D + Sbjct: 372 THVMEEMKELIIQNYNHPSILFWGISNEILIGGISQELVDTHHD---------------L 416 Query: 490 RKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKA 549 +K+ D +R + ++ + I+ D+ YN+ + KI Sbjct: 417 QKLCKELDPTRLTTIAHVSHTPTSGPMHRIT---------DVESYNHYFGWYGGKIEQNG 467 Query: 550 RLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHF 603 + ++ ++ + + + ++S + + E+ + F Sbjct: 468 PWLDKFHAENPDICLGISEYGCEGIINWHSNTPQCKDYSEEYQALYHEYMAQAF 521 >6D89-C nrPDB Length = 595 Score = 151 bits (381), Expect = 1e-36, Method: Composition-based stats. Identities = 88/539 (16%), Positives = 170/539 (31%), Gaps = 90/539 (16%) Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK-DVN 138 Y F+ + + L F V+ A + N +G+ FT ++F+ITN++K N Sbjct: 103 YRKHFEYSLQPGKR--LFLNFGAVNYEAIVWLNGKRLGRHIGGFTPFNFEITNLLKEGTN 160 Query: 139 SLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPS 198 SL ++ + R+P P V W++G Sbjct: 161 SLVVKV--------------DNKRLPEAVPTVNAD---------------WWNFG----- 186 Query: 199 QGIWKDVRIEAYNIAHL-DYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQ 257 GI + V + ++ DY L D ++++ S ++T+ IP+ Sbjct: 187 -GITRPVTLIEMPATYIRDYYVQLAKDDKNMIEGWVQLEGSDKEQ-------KITLDIPE 238 Query: 258 LKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEK 317 LK ++ L+ W P N Y + + + Sbjct: 239 LKV--KKEVTTDANGYASFLIKS-----KPILWTP---ENPKLYAVNL-----ASETDKV 283 Query: 318 AAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSF--QDKVTSDRLQLL 375 + ++ FRT++ +N IF +G + + + D L Sbjct: 284 SDEIGFRTIRTE----------GIKILLNDKEIFCRGISIHEETPYYSGRAYSKDHAHTL 333 Query: 376 FQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMFASALYPTEPGFLASVRK 434 + N +R+ Y +E + +G +VW + ++ + + Sbjct: 334 LSWAKELGCNFVRL---AHYPHNEEMVREAERMGFLVWSEIPVYWTIHWENKDTYQNAEQ 390 Query: 435 EVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVL 494 ++ + R K+ +IIIWS NE + + F N + +D V L + K + Sbjct: 391 QLCDMIARDKNRCNIIIWSIANETPHSKTRLTFLSNLANKARSLDS-VRLIGAAMEKEEV 449 Query: 495 SEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSE 554 + + E YD S + D + + K +SE Sbjct: 450 QPGVLTVNDPLGELLDIISFNEYVGWYDGDS-EKCDRVNWTFDTQ--------KPVFISE 500 Query: 555 YGYQSWPSFSTL--EKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDP 611 G + E+ + + R G + F+ P+ P Sbjct: 501 LGGGALYGHHGSPKERFTEEYQEDLYIRHVNM-LKRIPGLAGTTPWILKDFRSPRRHVP 558 >6NCZ-A nrPDB Length = 610 Score = 150 bits (379), Expect = 2e-36, Method: Composition-based stats. Identities = 80/561 (14%), Positives = 166/561 (29%), Gaps = 100/561 (17%) Query: 60 DPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKT 119 DP Y + + ++ +F + V L + + + N +G Sbjct: 97 DPMYLLYEGSM--------VFTRKFSYIAE--REETVFLKVGAANYLCRVFLNGKYVGMH 146 Query: 120 DNMFTGYSFDITNVVKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVN 179 T ++IT +K N + +VP E Sbjct: 147 RGGSTPAFWNITEYLKAEN----------RIVLAVDGTRRPEQVPTENT----------- 185 Query: 180 FIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASF 239 DW F G+++D+ + H+ V D ++ S Sbjct: 186 -----------DW---FNYCGVYRDIALIRVPKCHIKTFKIALVPDGTFGHVMAKVTLS- 230 Query: 240 DVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQT 299 + + + + I +L + +E + + E W P Sbjct: 231 -----EKITAKAELVIEELGVSRKIQLENGAGEVVFD--------AKPELWTP---EKPK 274 Query: 300 GYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIP 359 Y++ + + +V FR +++ +NG P+FL+G + Sbjct: 275 LYDVKVTC-----GTDTVSDRVGFREIRV----------NGRDILLNGEPVFLRGISCHE 319 Query: 360 AD-SFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDE-FYALCDELGIMVWQDFMF 417 +T + + + N +R+ Y +E L DELG+++W++ Sbjct: 320 DSVENGKGLTREERIENIRIAKELGCNFMRL---AHYPHNEEMAKLADELGLLLWEEIPV 376 Query: 418 ASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTY 477 A+ + ++ + R + S+IIWS NEN F + Sbjct: 377 YWAIRFEREKTYEDAQNQLRELINRDWNRASVIIWSVGNENADTDERLKFMSVLAECAHR 436 Query: 478 IDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYA 537 D+ + + ++ + R + + E Y P + Sbjct: 437 EDETRMVSAACLVNAAKNKIEDRL----MEYLDIIGINEYCGWYTPD---------FAML 483 Query: 538 DDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWA---YNSRFSLHRQHHEDGNHQ 594 K +V+E+G + P E+ Y + + R Sbjct: 484 PALMENSQPDKPVIVTEFGADALPHHHGTISDKGTEECQADVYEKQIATLRNIDYI--KG 541 Query: 595 MLHQVKMHFKLPQGTDPLRTF 615 M + F+ P+ T ++ + Sbjct: 542 MTPWILYDFRCPRRTSLIQKY 562 >3CMG-A nrPDB Length = 667 Score = 150 bits (378), Expect = 3e-36, Method: Composition-based stats. Identities = 89/518 (17%), Positives = 182/518 (35%), Gaps = 96/518 (18%) Query: 92 EWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQFRSAVQYA 151 + +++ L FDGV+++A++ N IG+ + + F+IT++VK Sbjct: 64 KGKRLFLRFDGVNSIADVFINRKHIGEHRGGYGAFIFEITDLVK---------YGEKNSV 114 Query: 152 ECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYN 211 ++ + P G GI++DV + + Sbjct: 115 LVRANNGEQLDIMPLVGDFNFYG-------------------------GIYRDVHLLITD 149 Query: 212 IAHLDYLTFLP--------VYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQT 263 + L + V ++ S A + + ++ +++ Sbjct: 150 ETCISPLDYASPGVYLVQEVVSPQEAKVCAKVNLSNRAADGTAELQVLVTDGTKVICKES 209 Query: 264 NDIELQQEQRIV-KLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVY 322 ++ L+Q I+ +L + I+K W G + Y ++I DG + Sbjct: 210 RNVSLKQGADILEQLPLLIQKP---RLW--NGCEDPFMYQVSISLHKDGKQIDSVTQPLG 264 Query: 323 FRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPA-----DSFQDKVTSDRLQLLFQ 377 R F +NG + L G ++ + + + + L Sbjct: 265 LRYYHTDP---------DKGFFLNGKHLPLHGVCRHQDRAEVGNALRPQHHEEDVAL--- 312 Query: 378 SVVDANMNTLRVWGGGIYEQDEF-YALCDELGIMVWQDFMF------ASALYPTEPGFLA 430 + + +N +R+ Y Q + Y L D+ GI+ W + F A + + F Sbjct: 313 -MREMGVNAIRL---AHYPQATYMYDLMDKHGIVTWAEIPFVGPGGYADKGFVDQASFRE 368 Query: 431 SVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIR 490 + ++++ +R+ +HPSI W NE NP + YVK + Sbjct: 369 NGKQQLIELIRQHYNHPSICFWGLFNEL------KEVGDNPVE-----------YVKELN 411 Query: 491 KIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKAR 550 + ED +RP ++S +G I+++ Y YG K P+ R Sbjct: 412 ALAKQEDPTRPTTSASNQDGNLNFITENIAWNRYDGWYGSTPKTLATFLDRTHKKHPELR 471 Query: 551 L-VSEYGYQS--WPSFSTLEKVSSQEDWAYNSRFSLHR 585 + +SEYG + + +L++ S+ W + + + Sbjct: 472 IGISEYGAGASIYHQQDSLKQPSASGWWHPENWQTYYH 509 >6B6L-A nrPDB Length = 776 Score = 148 bits (374), Expect = 7e-36, Method: Composition-based stats. Identities = 94/554 (16%), Positives = 179/554 (32%), Gaps = 97/554 (17%) Query: 11 LFRAGCVVAGPSYSLSGS-WRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLN 69 LF G + G SL S WR N +PG P+ Sbjct: 15 LFHRGDIAEGEKQSLDDSQWRQINLP-HDWSIEDIPGT-----------NSPFTADAATE 62 Query: 70 YR---WISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGY 126 + W Y F I + + + + FDG+ A+I N+ + +T + Sbjct: 63 VAGGFTVGGTGW-YRKHFYIDAAE-KGKCIAVSFDGIYMNADIWVNDRHVANHVYGYTAF 120 Query: 127 SFDITNVVK--DVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKA 184 DIT+ V+ N + ++ ++ Sbjct: 121 ELDITDYVRFGAENLIAVR-------------------------------------VKNE 143 Query: 185 QCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLP-VYDNASQAWNIEIKASFDVAS 243 + W + GI++ ++ N H + T+ V + A E+ +A+ Sbjct: 144 GMNCRW-----YTGSGIYRHTFLKITNPLH--FETWGTFVTTPVATADKAEVHVQSVLAN 196 Query: 244 SKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDV-------AVETWWPRGHG 296 ++ V G+V + + + N+ + +++++V L K + +V A + W Sbjct: 197 TEKVTGKVIL---ETRIVDKNNHTVARKEQLVTLDNKEKTEVGHALEVLAPQLWSID--- 250 Query: 297 NQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKG-S 355 N Y + D + E+ + R + E F++NG + LKG Sbjct: 251 NPYLYQVVNRLLQDDKVIDEEYISIGIRNIAFSAENG---------FQLNGKSMKLKGGC 301 Query: 356 NWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDF 415 K + + + A N LR+ CD LG++V + Sbjct: 302 IHHDNGLLGAKAFDRAEERKIELLKAAGFNALRLSHN--PPSIALLNACDRLGMLVIDEA 359 Query: 416 --MFASALYPTE--PGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNP 471 M+ Y + F ++++ V R ++HPS+I+WS NE + + + Sbjct: 360 FDMWRYGHYQYDYAQYFDKLWKEDLHSMVARDRNHPSVIMWSIGNEIKNKETAEIVDICR 419 Query: 472 RDMKTY--IDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYG 529 +D + + ++D P + E P I Y Sbjct: 420 ELTGFVKTLDTTRPVTAGVNSIVDATDDFLAPLDVCGYNYCLNRY-ESDAKRHPDRIIYA 478 Query: 530 DIHFYNYADDCWNW 543 + + A D W Sbjct: 479 SESYASQAYDYWKG 492 >5DMY-A nrPDB Length = 904 Score = 146 bits (368), Expect = 4e-35, Method: Composition-based stats. Identities = 72/480 (15%), Positives = 149/480 (31%), Gaps = 96/480 (20%) Query: 22 SYSLSGSWRVSNGNG-SLELPATVPGYVHS-ALHQHGLIQDPYYRFNDLNYRWISLDNWT 79 + +W+ + + PA L I Y + N+ ++ Sbjct: 38 TSDFDANWKFMLSDSVQAQDPAFDDSAWQQVDLPHDYSITQKYSQSNEAESAYLPGGTGW 97 Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK--DV 137 Y F I +L+ +++ + FDGV A + FN V +G ++ +SFD+T K Sbjct: 98 YRKSFTIDRDLAG-KRIAINFDGVYMNATVWFNGVKLGTHPYGYSPFSFDLTGNAKFGGE 156 Query: 138 NSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFP 197 N++ ++ E + R W + Sbjct: 157 NTIVVKV------------------------------ENRLPSSR---------W---YS 174 Query: 198 SQGIWKDVRIEAYNIAHLDYLTFL------PVYDNASQAWNIEIKASFDVASSKSVGGQV 251 GI++DV + + H+ + + N+ K + D ++ ++ + Sbjct: 175 GSGIYRDVTLTVTDGVHVGNNGVAIKTPSLATQNGGNVTMNLTTKVANDTEAAANITLKQ 234 Query: 252 TVAIPQLKTQQTNDIELQQEQRI-----VKLLVKIRKDVAVETWWPRGHGNQTGYNMTIL 306 TV KT + I + I + + W + N Y + Sbjct: 235 TVFPKGGKTDAAIGTVTTASKSIAAGASADVTSTIT-AASPKLWSIK---NPNLYTVRTE 290 Query: 307 FALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSN-WIPADSFQD 365 + + FR F +NG + LKG + S Sbjct: 291 VLNGDTVLDTYDTEYGFRWTGFDATSG---------FSLNGEKVKLKGVSMHHDQGSLGA 341 Query: 366 KVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDF--MFASALYP 423 ++ + + +N++R +C+E G++V ++ M+ + Sbjct: 342 VANRRAIERQVEILQKMGVNSIRTTHN--PAAKALIDVCNEKGVLVVEEVFDMWNRSKNG 399 Query: 424 TEPGFLA--------------------SVRKEVTYQVRRLKSHPSIIIWSGNNENEVALS 463 + + ++T + R ++ PS+I+WS NE +S Sbjct: 400 NTEDYGKWFGQTIAGDNAVLGGDKDETWAKFDLTSTINRDRNAPSVIMWSLGNEMMEGIS 459 >5Z1B-A nrPDB Length = 692 Score = 141 bits (354), Expect = 2e-33, Method: Composition-based stats. Identities = 109/709 (15%), Positives = 203/709 (28%), Gaps = 140/709 (19%) Query: 25 LSGSWRVS----NGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWT- 79 L G W + + A +P + A + Y ND + W Sbjct: 39 LDGVWDFRTAGEDSYPAEWADAPLPEPLPMA------VPGSYNDQND-ELNLRAHYGWVV 91 Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVV-KDVN 138 Y F +P L Q++ L FD A++ N +G F + FD+T+ + N Sbjct: 92 YQRSFAVPSRLVAGQRMILRFDAATHAADVYLNGQLLGSHFGGFLPFEFDVTSALHAGEN 151 Query: 139 SLKLQFRSAVQYAECQSKAHTSYRVPPE---CPPVEQKGECHVNFIRKAQCSFSWDWGPS 195 L + + + + P + + H F Sbjct: 152 LLTVAVDNRIGSSTLPVGNDAGTAFMGSDNANVPAVAEAKKHARRQNLPNFDF------- 204 Query: 196 FPSQGIWKDVRIEAYNI-AHLDYLTFLPVY-DNASQAWNIEIKA---------------- 237 F G+ + V + A++ + D+ + A Sbjct: 205 FNFAGLNRHVELYTTPADAYIADIAITTERLDHIAGDACTAANALIAYDVTFGGDFPSNP 264 Query: 238 -----------------------SFDVASSKSVGGQVTVAIPQLKTQQTNDIELQ---QE 271 D+ + + G QV ++I + + Sbjct: 265 TDPNTLIQPSDPAINHADPSESSESDIQRTATYGRQVRISILDGEGTVVAGVTADIERSG 324 Query: 272 QRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKA------AKVYFRT 325 K +I A + W P G Y +GG + RT Sbjct: 325 DGTAKASGEIAIRDA-KLWNP---GAAYLYTAVAELLPEGGAESSSRIIDAYRQTFGIRT 380 Query: 326 VQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQL-LFQSVVDANM 384 V++ F ING P + KG F + T D L + + + Sbjct: 381 VEV----------SGTTFLINGKPFYFKGFGKHEDSYFHGRGTDDVLNVKDVSLIHWLHA 430 Query: 385 NTLRVWGGGIYE-QDEFYALCDELGIMVWQDFMFASALYPT--EPGFLASVRKEVTYQVR 441 N+ R Y + Y LCD GI++ + + P R+ + + Sbjct: 431 NSFRT---SHYPYAESMYDLCDREGIVIIDEVPAVGMSWLQYANPLVAERHREAIRGMIA 487 Query: 442 RLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDK-SR 500 R K+HP I++WS N L + + DY + ++ + D +R Sbjct: 488 RDKNHPCIVMWSIAN--APGLDGD------GERPRQAYDYFR----PLYELAHASDPQNR 535 Query: 501 PFIA----SSPTNGMKTMEEGWISYDPYSIQYG-----DIHFYNYADDCWNWKIFPKARL 551 P + T + + + Y Y D + + W+ K + Sbjct: 536 PVTLVCCQNDYTTDITERTMDVVCINRYYGWYNLSGDLDAACHALNIELDFWENIGKPVM 595 Query: 552 VSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDP 611 +EYG + E++ R ++ N ++ K + + + Sbjct: 596 FTEYGADTIEGIHGTHGEMFSEEFQ--------RDYYARINAEID---KRPWFIGEQ--- 641 Query: 612 LRTFKDTIYLTQVMQAQCIKTET----------EFYLRSRSEIVDGKGH 650 L F D +++ + + +LR R + G+ Sbjct: 642 LWNFADFATFQGIIRVEGNRKGILTRDRQPKMAAHWLRERWAGIPDYGY 690 >3FN9-A nrPDB Length = 692 Score = 138 bits (348), Expect = 7e-33, Method: Composition-based stats. Identities = 68/448 (15%), Positives = 144/448 (32%), Gaps = 88/448 (19%) Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK--DV 137 Y P + E ++V L F+GV AE+ N G ++ ++ +I +K Sbjct: 64 YRKTQFFPHD-LEGKRVFLRFEGVGACAEVYVNGKLAGTHKGGYSAFACEIGTALKLGAE 122 Query: 138 NSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFP 197 N + ++ + + P+ PV Q F Sbjct: 123 NEIIVKADNKAR---------------PDVIPVN-------------QNLFG-------V 147 Query: 198 SQGIWKDVRIEAYNIAHL-------DYLTFLPVYDNASQAWNIEIKASFDVASSKSVGG- 249 GI++ V + ++ + + A +I +K D A + Sbjct: 148 YGGIYRPVWLIVTEQNNITVTDCASPGVYITQKDVSKKSA-DITVKVKLDNAGLQPAAVT 206 Query: 250 ---QVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTIL 306 + Q + +L + + + K W +G + Y + Sbjct: 207 LENTIYTQEGQKVGTHSRSFDLSPQG--TQTYLSTFKLKNPHLW--QGRKDPYLYKVVCR 262 Query: 307 FALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPA-DSFQD 365 DG + E + R +++ F +NG + G Sbjct: 263 LMADGKVIDEVVQPLGVRKYEIVAGKG---------FFLNGEKYSMYGVTRHQDWWGLGS 313 Query: 366 KVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQ-DEFYALCDELGIMVWQDFMFASALYPT 424 + ++ +++D T+R Y+Q D Y+ CD LG+++W + + + Sbjct: 314 ALKNEHHDFDLAAIMDVGATTVRF---AHYQQSDYLYSRCDTLGLIIWAEIPCVNRVTGY 370 Query: 425 EPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTL 484 E + + ++ +R+ +HPSI +W +NE +Y Sbjct: 371 E---TENAQSQLRELIRQSFNHPSIYVWGLHNEV-----------------YQPHEYTAA 410 Query: 485 YVKNIRKIVLSEDKSRPFIASSPTNGMK 512 +++ + +ED R ++ + M Sbjct: 411 LTRSLHDLAKTEDPDRYTVSVNGYGHMD 438 >6ED2-A nrPDB Length = 631 Score = 138 bits (347), Expect = 9e-33, Method: Composition-based stats. Identities = 115/658 (17%), Positives = 213/658 (32%), Gaps = 115/658 (17%) Query: 25 LSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLD---NWTYS 81 L G WR S S + A G+ L + P F DL S + ++ Y Sbjct: 42 LDGMWRFSFDPESKGVEA---GWA-LDLPSSLSMPVP-ASFCDLFTDKASREYCGDFWYE 96 Query: 82 TEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLK 141 T F +P S W + L F V A + N V + + + F + +TN+V+ K Sbjct: 97 TSFFVPAEWSGWD-IVLRFGSVTHRARVFVNGVEVAQHEGGFLPFDATVTNIVRYNQFNK 155 Query: 142 LQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGI 201 L + + +E A T+ C + RK + +D+ + GI Sbjct: 156 LSVLANNELSETMLPAGTT---------------CTLADGRKIAAPY-FDF---YNYAGI 196 Query: 202 WKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQ 261 + V + A + D +++ E A D S + VTV + Sbjct: 197 HRPVWLMALPKERV--------LDYSTRYRLTETGAEIDYTVSTNGPHPVTVELYDG--- 245 Query: 262 QTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKV 321 T + ++ R W Y++ I + E ++ Sbjct: 246 -TTRVAESSGTTGTLVVKNAR------LW---NVHAAYLYDLVIRIHEGSAVVDEYLDRI 295 Query: 322 YFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIP-ADSFQDKVTSDRLQLLFQSVV 380 RT ++ F +NG P++L+G AD + ++ F+ + Sbjct: 296 GIRTFEIR----------HGRFLLNGSPVYLRGFGRHEDADIRGRGLDLPTVKRDFELMK 345 Query: 381 DANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQDFM----------FASALYPTE---- 425 N R Y +E Y + DE G ++ + F +A Sbjct: 346 WIGANCFRT---SHYPYAEEIYQMADEEGFLIIDEVPAVGFMQSTANFLAANQGNGRQQG 402 Query: 426 -------PGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPR-DMKTY 477 P L + + +T + R K+HPS+I WS NE + + + P ++ Sbjct: 403 FFEKETTPALLKNHKAALTDMIDRDKNHPSVIAWSLLNEPQCTSAGTEEYFKPLFELARR 462 Query: 478 ID-----DYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIH 532 +D T+ + ++ + + + GW + + Sbjct: 463 LDPQKRPRTYTVLMTSLPDTSKGQRFADFVSLNRYY--------GWYVLGGAGLADAEAA 514 Query: 533 FYNYADDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGN 592 F+ + D W + + + +EYG + L V Y + + Sbjct: 515 FH-HEMDGWAKVLHGRPLIFTEYGTDNLSGAHKLPSVM--WSAEYQNEYL---------- 561 Query: 593 HQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGH 650 +M H V H+ QG + + F D +++ K F + + + Sbjct: 562 -EMTHAVFDHYDFVQG-ELVWNFADFQTTEGILRVDGNKKGI-FTRQRQPKDAAYLFR 616 >3HN3-A nrPDB Length = 613 Score = 138 bits (347), Expect = 1e-32, Method: Composition-based stats. Identities = 116/663 (17%), Positives = 201/663 (30%), Gaps = 102/663 (15%) Query: 25 LSGSWRVSNGNGSLELPATVPGYVHSALHQHGL-----IQDPYYRFNDLNYRWISLDNWT 79 L G W + L + G + + + ++R W Sbjct: 21 LDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQ-DWRLRHFVGWV 79 Query: 80 -YSTEFKIPFNLSE--WQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKD 136 Y E +P ++ +V L + A + N V + + + + DI+N+V+ Sbjct: 80 WYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQ- 138 Query: 137 VNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVN--FIRKAQCSFSWDWGP 194 S ++ + T +PP + F++ F Sbjct: 139 ----VGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYFVQNTYFDF------ 188 Query: 195 SFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVA 254 F G+ + V + ++D +T + S N +I V S +V + Sbjct: 189 -FNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQIS----VKGSNLFKLEVRLL 243 Query: 255 IPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLK 314 + K Q K V WWP + Y ++ L Sbjct: 244 DAENKVVANGTGTQGQL-----------KVPGVSLWWPYLMHERPAYLYSLEVQLTAQTS 292 Query: 315 IEKA-----AKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIP-ADSFQDKVT 368 + V RTV + + F ING P + G N AD Sbjct: 293 LGPVSDFYTLPVGIRTVAVTKS----------QFLINGKPFYFHGVNKHEDADIRGKGFD 342 Query: 369 SDRLQLLFQSVVDANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQDFMFASALYPT--E 425 L F + N R Y +E +CD GI+V + P Sbjct: 343 WPLLVKDFNLLRWLGANAFRT---SHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFN 399 Query: 426 PGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLY 485 L + + VRR K+HP++++WS NE P Y+ + Sbjct: 400 NVSLHHHMQVMEEVVRRDKNHPAVVMWSVANE-------------PASHLESAGYYLKMV 446 Query: 486 VKNIRKIVLSEDKSRP--FIASSPTNGMKTMEEGWI----SYDPYSIQYGDIHF--YNYA 537 + + S D SRP F+++S K + SY + YG + A Sbjct: 447 IAH----TKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLA 502 Query: 538 DDCWNWK-IFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQML 596 NW + K + SEYG ++ F + E++ SL Q+H + + Sbjct: 503 TQFENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQ----KSLLEQYHLGLDQKRR 558 Query: 597 HQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALY 656 V + F D + + K F + + + Y Sbjct: 559 KYVVGEL--------IWNFADFMTEQSPTRVLGNKKGI-FTRQRQPKSAAFLLRER---Y 606 Query: 657 WQL 659 W++ Sbjct: 607 WKI 609 >6CXS-A nrPDB Length = 602 Score = 138 bits (346), Expect = 1e-32, Method: Composition-based stats. Identities = 104/661 (15%), Positives = 213/661 (32%), Gaps = 124/661 (18%) Query: 25 LSGSWRVSNGNGS------------LELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRW 72 LSG W+ G+ + VP ++ L + ++D + W Sbjct: 18 LSGIWKFKLNEGNGLTEELSKAPLEDTIEMAVPSS-YNDLVESQEVRD--------HVGW 68 Query: 73 ISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITN 132 + W Y F IP L +++ L F A++ N + + FT + +I + Sbjct: 69 V----W-YERNFTIPKTLLN-ERIVLRFGSATHEAKVYLNGELLVEHKGGFTPFEAEIND 122 Query: 133 VV-KDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWD 191 ++ N L + + + + VE G+ + K +F + Sbjct: 123 LLVSGDNRLTVAVNNII---------DETTLPVGLVKEVEVDGKK----VIKNSVNFDF- 168 Query: 192 WGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQV 251 F GI + V+I ++++ +T + + + N E++A +V Sbjct: 169 ----FNYAGIHRPVKIYTTPKSYIEDITIVTDFKENNGYVNYEVQA------VGKCNIKV 218 Query: 252 TVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDG 311 T+ + N+I + E + KL + V W P N Y + + D Sbjct: 219 TIIDEE------NNIVAEGEGKEGKLTIN-----NVHLWEPM---NAYLYKLKVELLDDE 264 Query: 312 GLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDR 371 + + RTV++ F IN P + KG + ++ Sbjct: 265 EIIDTYFEEFGVRTVEV----------KDGKFLINNKPFYFKGFGKHEDSYVNGRGINEA 314 Query: 372 LQL-LFQSVVDANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQDFM-------FASALY 422 + + F + N+ R Y +E L D GI+V + F + + Sbjct: 315 INIKDFNLMKWIGANSFRT---SHYPYSEEIMRLADREGIVVIDETPAVGLHLNFMATGF 371 Query: 423 PTEPGFLASV---------RKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRD 473 + + + + V R K+HP +++WS NE + + P Sbjct: 372 GGDAPKRDTWKEIGTKEAHERILRELVSRDKNHPCVVMWSVANEPDSDSEGAKEYFEPLI 431 Query: 474 MKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHF 533 T D V + ++ + D+ + + + Y + + GD+ Sbjct: 432 KLTKELDPQKRPVTVVTYLMSTPDR------CKVGDIVDVLCLN--RYYGWYVAGGDLEE 483 Query: 534 YN--YADDCWNWKIF--PKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHE 589 D+ W+ + +EYG + V E++ + Sbjct: 484 AKRMLEDELKGWEERCPKTPIMFTEYGADTVAGLHDTVPVMFTEEYQVE---------YY 534 Query: 590 DGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKG 649 NH+++ + K + F D +++ Q K F + +++ Sbjct: 535 KANHEVMDKCKNFVGE-----QVWNFADFATSQGIIRVQGNKKGI-FTRERKPKMIAHSL 588 Query: 650 H 650 Sbjct: 589 R 589 >4CUC-A nrPDB Length = 849 Score = 136 bits (341), Expect = 5e-32, Method: Composition-based stats. Identities = 86/551 (15%), Positives = 157/551 (28%), Gaps = 105/551 (19%) Query: 74 SLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNV 133 + W Y FK+ + + V+L FDGV +++ N +G N + +S+DIT Sbjct: 73 GGEAW-YRKTFKLDEKDLK-KNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKY 130 Query: 134 VKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWG 193 ++ G +V + S W Sbjct: 131 LQKD------------------------------------GRENVIAVHAVNKQPSSRW- 153 Query: 194 PSFPSQGIWKDVRIEAYNIAHLDYL---TFLPVYDNA-SQAWNIEIKASF---DVASSKS 246 + GI++DV ++ + H++ P + + + D + Sbjct: 154 --YSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVTSKIVNTDDKDHEL 211 Query: 247 VGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTIL 306 V V + + + +V W + Y + Sbjct: 212 VAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLWTVLNDKPALYELITR 271 Query: 307 FALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSN-WIPADSFQD 365 DG L K +R F +NG I G + + Sbjct: 272 VYRDGQLVDAKKDLFGYRYYHWTPNEG---------FSLNGERIKFHGVSLHHDHGALGA 322 Query: 366 KVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMF----ASAL 421 + + + + +N++R EQ + ELG++V ++ Sbjct: 323 EENYKAEYRRLKQMKEMGVNSIRTTHNPASEQT--LQIAAELGLLVQEEAFDTWYGGKKP 380 Query: 422 YPTEPGFLASVRK------------EVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHV 469 Y F ++ V R K++P+I +WS NE A Sbjct: 381 YDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIGEANG------ 434 Query: 470 NPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASS----PTNGMKTMEEGWISYDPYS 525 D + VK + K++ DK+R + NG E+ D Sbjct: 435 ---------DAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVG 485 Query: 526 IQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHR 585 Y + ++ W I YG Q+ + T E +S Sbjct: 486 FNYSEDNYKALRAKHPKWLI---------YGSQTSSATRTRGSYYRPERELKHSNGPERN 536 Query: 586 QHHED-GNHQM 595 D GN ++ Sbjct: 537 YEQSDYGNDRV 547 >5Z19-A nrPDB Length = 627 Score = 126 bits (316), Expect = 4e-29, Method: Composition-based stats. Identities = 91/589 (15%), Positives = 169/589 (28%), Gaps = 89/589 (15%) Query: 24 SLSGSWRVSNGNGSLELPAT----VPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWT 79 SL G W+ + + +P V + D + + +Y ++ Sbjct: 43 SLDGMWKFQFDPEEIGKKSGWENGLPAPVSMPVPSS--FADFFTDHKERDY----CGDFW 96 Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNS 139 Y TEF +P +K+ L F + + N + I + F DI+ V K Sbjct: 97 YETEFYLPAEWRN-KKIWLRFGSITHRGTVYCNGMEITSHEGGFLPVLADISTVAKP--- 152 Query: 140 LKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQ 199 Q + +P + G + K F F Sbjct: 153 -----GQVNQVVVKINNELNETSLPCGATKILNNGRK----LAKPYFDF-------FNYS 196 Query: 200 GIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLK 259 G+ + V + A + + E+ + + V V + + Sbjct: 197 GLQRSVWVIALPEESVKDYSVDYELCGTDALVKYEVVTTGE--------HPVIVRLLDAE 248 Query: 260 TQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAA 319 + + E ++ I + W R N Y + IL G+ E Sbjct: 249 GELVAETEGKEG---------ILQVANARLWEVR---NAYLYQIVILITDGNGVLDEYRE 296 Query: 320 KVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPA-DSFQDKVTSDRLQLLFQS 378 K+ RTV++ +N P++LKG ++ F+ Sbjct: 297 KIGIRTVRIE----------GTKILLNDRPVYLKGFGKHEDFPILGRGFHWGIVKRDFEC 346 Query: 379 VVDANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQDFM----------FASALYPT--- 424 + N N R Y +E+Y DE G ++ + F +A Sbjct: 347 LKWTNANCFRT---SHYPYAEEWYQFADEEGFLIIDEVPAVGMMRSTRNFVAAGSGNYTY 403 Query: 425 ------EPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYI 478 P L S + + R K+HPS+I WS NE E + + Sbjct: 404 FFEALTVPELLKSHIADTEEMITRDKNHPSVIAWSLFNEPETITDYAYEYFKEVFAAAET 463 Query: 479 DDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDI-HFYNYA 537 D+ + + ++ P + + Y + + + Sbjct: 464 YDFQSRPMTG----AFEKNSKPELCKCYPLCDFICLNRYYGWYISGGPEIEEAEELFRDE 519 Query: 538 DDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQ 586 D W K + +E+G + L + E++ R Sbjct: 520 MDRWKAKELNVPFVFTEFGTDTMAGLHKLPSIMWSEEYQKEYLEMNFRV 568 >4JKL-A nrPDB Length = 602 Score = 125 bits (314), Expect = 7e-29, Method: Composition-based stats. Identities = 86/584 (14%), Positives = 183/584 (31%), Gaps = 81/584 (13%) Query: 22 SYSLSGSWRVSNG--NGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWT 79 +Y L G W G N + LP+ + +I + + + ++ Sbjct: 15 TYDLGGIWNFKLGEHNPNELLPSD----------EVMVIPTSFNDLMVSKEKRDYIGDFW 64 Query: 80 YSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNS 139 Y ++P +SE +++ L F V A+I + V +G+ FT + + + Sbjct: 65 YEKVIEVPK-VSEDEEMVLRFGSVTHQAKIYVDGVLVGEHKGGFTPFEVLVPECKYNNEK 123 Query: 140 LKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQ 199 +K+ C + +P + + + + F F Sbjct: 124 IKVSI--------CANNVLDYTTLPVGNYSEIIQEDGSIKKKVRENFDF-------FNYA 168 Query: 200 GIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLK 259 G+ + +++ H+ +T + +S V Q Sbjct: 169 GVHRPLKLMIRPKNHIFDITITSRLSD----------------DLQSADLHFLVETNQKV 212 Query: 260 TQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAA 319 + + + + + + V W N Y + +D L+ Sbjct: 213 DEVRISVFDEDNKLVGETKDSRLFLSDVHLW---EVLNAYLYTARVEIFVDNQLQDVYEE 269 Query: 320 KVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLL-FQS 378 R +++ + F +N PI+ KG + ++ L+ Sbjct: 270 NFGLREIEV----------TNGQFLLNRKPIYFKGFGKHEDTFINGRGLNEAANLMDLNL 319 Query: 379 VVDANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQDFM-------FASALY--PTEPGF 428 + D N+ R Y +E L D +G++V + F ++L P + G Sbjct: 320 LKDMGANSFRT---SHYPYSEEMMRLADRMGVLVIDEVPAVGLFQNFNASLDLSPKDNGT 376 Query: 429 ------LASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYV 482 A+ + + V+R K+HPS+++W NE + + P D Sbjct: 377 WNLMQTKAAHEQAIQELVKRDKNHPSVVMWVVANEPASHEAGAHDYFEPLVKLYKDLDPQ 436 Query: 483 TLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWN 542 V + ++ + D+ + + D + + G W Sbjct: 437 KRPVTLVNILMATPDRDQVMDLVDVVCLNRYYGWYVDHGDLTNAEVGIR----KELLEWQ 492 Query: 543 WKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQ 586 K K +++EYG + P + + E++ + HR Sbjct: 493 DKFPDKPIIITEYGADTLPGLHSTWNIPYTEEFQCDFYEMSHRV 536 >5EUV-A nrPDB Length = 731 Score = 125 bits (312), Expect = 1e-28, Method: Composition-based stats. Identities = 88/565 (15%), Positives = 161/565 (28%), Gaps = 115/565 (20%) Query: 24 SLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTE 83 L+ W + G PAT P + H + P F++ +Y+ +TY Sbjct: 6 KLNHGWIFAEGAAD---PAT-PLAGETVTLPHNAVDLPLSYFDETSYQRA----FTYQ-- 55 Query: 84 FKIPFNLSEWQK--VKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVK-DVNSL 140 ++ WQ V+L FDG + N V + + +T + D+T+ ++ N + Sbjct: 56 -RVIAWDDAWQGRRVQLRFDGAMADNVVWVNGVQVVAHPDGYTPFVADLTDHLRPGDNLV 114 Query: 141 KLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQG 200 ++ P +++ G Sbjct: 115 TVRI-------------------DGSENPAIPPFGAQIDY---------------LTYAG 140 Query: 201 IWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKT 260 I++DV + HL L D S A + I+ + + + + Sbjct: 141 IYRDVWLMVLPERHLTNARILTP-DALSDAKTVVIRPEV----TAPGPVRARLLDGDREI 195 Query: 261 QQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAK 320 T + + + + W N Y + + G + Sbjct: 196 AATEG----------EGELTLAGLTGLSLWSTD---NPQLYTVELTLPDSG---DVTTHR 239 Query: 321 VYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIP--ADSFQDKVTSDRLQLLFQS 378 FRT + +G F +NG P+ L+G N A + + Sbjct: 240 FGFRTAEWTPQG----------FLLNGQPMKLRGLNRHQSWAHQGYAAGRHAQERDAEIV 289 Query: 379 VVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTY 438 D N +R + F CDE+G++V+++ + + + V Sbjct: 290 RHDLCCNMVRT--SHYPQSTWFLDRCDEIGLLVFEEIPGWQHI--GDQAWQDRSVDNVRA 345 Query: 439 QVRRLKSHPSIIIWSGN-NE---NEVALSVNWFHVNPRDMKTYIDDY-VTLYVKNIRKIV 493 + R +HPSI+IW NE N D I + + + Sbjct: 346 MITRDWNHPSIVIWGVRINESPDNHDFYVRTNALARELDPTRAIGGVRCITDSEMLEDVY 405 Query: 494 LSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVS 553 D FI + + + P LV+ Sbjct: 406 TMND----FILDESELPLINRPRTALR----------------PTEEVTGIKKPVPYLVT 445 Query: 554 EYGYQSWPSFSTLEKVSSQEDWAYN 578 EY +P+ K E Sbjct: 446 EYNGHMFPT-----KAQDPELRQME 465 >6ECA-A nrPDB Length = 627 Score = 124 bits (311), Expect = 1e-28, Method: Composition-based stats. Identities = 98/591 (16%), Positives = 179/591 (30%), Gaps = 89/591 (15%) Query: 21 PSYSLSGSWRVS-NGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLD--- 76 L G W+ + G E G H + P FND S + Sbjct: 39 TDQKLDGLWQFKFDEAGEGEKSGWETG-----FHDGVSMPVP-ASFNDFFTDKASREYTG 92 Query: 77 NWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKD 136 ++ YS F +P ++ + + L FD V A I N I + F ++ DI+ Sbjct: 93 DFWYSRNFFVPSA-AKGKALFLRFDAVTHRATIFVNGKEIRTHEGGFLPFAADISE---- 147 Query: 137 VNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSF 196 +++ + + + +P + G+ V + F + Sbjct: 148 ----AVKYGAENTVVVKGNNELSREALPAGDTITLRNGKKMV----RPFFDF-------Y 192 Query: 197 PSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIP 256 G+ + V + + + T N ++ + D V++A Sbjct: 193 NYSGLNRSVHLLSLPQERVLDYTTTFALAGNDATVNYTVETNGDA------PVTVSLADA 246 Query: 257 QLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIE 316 + T + Q W R N Y +TI D ++ Sbjct: 247 DGQVVATAQGKQGALQVQ-----------NAHLWQVR---NAYLYTLTIQLGDDTQTPLD 292 Query: 317 K-AAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSF-QDKVTSDRLQL 374 ++ RT+++ +N PI+LKG F + + Sbjct: 293 TYTDRIGIRTIKI----------SGTDILVNDKPIYLKGFGRHEDSPFAGRAFDLNVEKK 342 Query: 375 LFQSVVDANMNTLRVWGGGIYEQD-EFYALCDELGIMVWQDFMFASALYP--------TE 425 F + N+ R Y D + Y + DE G ++ + + Sbjct: 343 DFALMKWIGANSFRT---SHYPYDEQVYKIADEEGFLLTDEVPAVGFKMAAAAFLGGLNQ 399 Query: 426 PGFLASVRKEV--------TYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTY 477 F K++ ++R K+HPS++ WS NE + + P + + Sbjct: 400 SFFKGPWLKKLHERHIDQIRDLIKRDKNHPSVLAWSLFNEPDTIDE----NAVPYFKQIF 455 Query: 478 IDDYVTLYVKNIRKIVLSEDKSR--PFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYN 535 + R LSED + + P M GW + Y I G+ + Sbjct: 456 DESKDLDPQGRPRTFTLSEDDTIETSKVLDFPDFYMLNRYPGWYHFGGYQISDGEAGLRD 515 Query: 536 YADDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQ 586 D W K + +E+G + L V E++ R Sbjct: 516 -EMDKWQKAGVKKPVVFTEFGADTEAGLHKLPSVMWTEEYQVEVLKMFSRV 565 >5C70-A nrPDB Length = 612 Score = 123 bits (307), Expect = 5e-28, Method: Composition-based stats. Identities = 90/609 (14%), Positives = 165/609 (27%), Gaps = 123/609 (20%) Query: 23 YSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYR-FNDLNYR----WISLDN 77 SL G W+ + + T P + Y F D W+ Sbjct: 21 ISLDGLWKFALASDDNN---TQPWTSQLKTSLECPVPASYNDIFADSKIHDHVGWV---- 73 Query: 78 WTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDV 137 Y + +P SE ++ + + I N + +T + DIT++V Sbjct: 74 -YYQRDVIVPKGWSE-ERYLVRCEAATHHGRIYVNGNLVADHVGGYTPFEADITDLVAA- 130 Query: 138 NSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFP 197 + T +PP + + V + ++ Sbjct: 131 -------GEQFRLTIAVDNELTYQTIPPGKVEILEATGKKVQTYQHDFYNY--------- 174 Query: 198 SQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQ 257 G+ + V + + H+ +T + + + VAS+ QV V Sbjct: 175 -AGLARSVWLYSVPQQHIQDITVRTDVQGTTGLIDYNV-----VASTTQGTIQVAVIDED 228 Query: 258 LKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEK 317 T T+ I +V W P G Y + I+ Sbjct: 229 GTTVATSS----------GSNGTIHIP-SVHLWQP---GAAYLYQLHASIIDSSKKTIDT 274 Query: 318 -AAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQL-L 375 RTV++ F IN P + G + + K D + Sbjct: 275 YKLATGIRTVKV----------QGTQFLINDKPFYFTGFGKHEDTNIRGKGHDDAYMVHD 324 Query: 376 FQSVVDANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQDFMFAS--------------- 419 FQ + N+ R Y +E D GI+V + Sbjct: 325 FQLLHWMGANSFRT---SHYPYAEEVMEYADRQGIVVIDETPAVGLAFSIGAGAQTSNPP 381 Query: 420 ---ALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKT 476 + + + + + R K+HPS+++WS NE Sbjct: 382 ATFSPDRINNKTREAHAQAIRELIHRDKNHPSVVMWSIANE-----------------PA 424 Query: 477 YIDDYVTLYVKNIRKIVLSEDKSRPF--------------IASSPTNGMKTMEEGWISYD 522 +D Y + K+ D +RP IA GW + Sbjct: 425 SNEDGAREYFAPLPKLARQLDPTRPVTFANVGLATYKADRIADLFDVLCLNRYFGWYT-- 482 Query: 523 PYSIQYGDIHFYNYADDCWNW-KIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRF 581 D ++ W + + K +++EYG + ++ + + + Sbjct: 483 --QTAELDEAEAALEEELRGWTEKYDKPIVMTEYGADTVAGLHSV--MVTPWSEEFQVEM 538 Query: 582 SLHRQHHED 590 D Sbjct: 539 LDMYHRVFD 547 >3K4D-A nrPDB Length = 605 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 96/587 (16%), Positives = 176/587 (29%), Gaps = 106/587 (18%) Query: 24 SLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTE 83 L G W S + + + +F D + R + + W Y E Sbjct: 16 KLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADIRNYAGNVW-YQRE 74 Query: 84 FKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQ 143 IP + Q++ L FD V ++ NN + + +T + D+T + Sbjct: 75 VFIPKGWAG-QRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTP--------YVI 125 Query: 144 FRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWK 203 +V+ C + +PP ++ G+ ++ F GI + Sbjct: 126 AGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHD-----------FFNYAGIHR 174 Query: 204 DVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQT 263 V + +D +T + + +Q N AS D + V + + T Sbjct: 175 SVMLYTTPNTWVDDITVVT---HVAQDCN---HASVDWQVVANGDVSVELRDADQQVVAT 228 Query: 264 NDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYF 323 Q V W P G Y + + A +V Sbjct: 229 GQGTSGTLQV-----------VNPHLWQP---GEGYLYEL-CVTAKSQTECDIYPLRVGI 273 Query: 324 RTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVD-A 382 R+V + E F IN P + G + K + L + +++D Sbjct: 274 RSVAVKGE----------QFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWI 323 Query: 383 NMNTLRVWGGGIYE-QDEFYALCDELGIMVWQD-----------FMFASALYPTEPGFLA 430 N+ R Y +E DE GI+V + F + P E Sbjct: 324 GANSYRT---SHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEE 380 Query: 431 SVRKE--------VTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYV 482 +V E + + R K+HPS+++WS NE P Sbjct: 381 AVNGETQQAHLQAIKELIARDKNHPSVVMWSIANE-------------PDTRP----QGA 423 Query: 483 TLYVKNIRKIVLSEDKSRP-----FIASSPTNGMKTMEEGWI---SYDPYSIQYGDIHFY 534 Y + + D +RP + + + Y + +Q GD+ Sbjct: 424 REYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLETA 483 Query: 535 N--YADDCWNW-KIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYN 578 + W + + +++EYG + ++ + Y Sbjct: 484 EKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSM--YTDMWSEEYQ 528 >6BJW-A nrPDB Length = 635 Score = 113 bits (281), Expect = 4e-25, Method: Composition-based stats. Identities = 89/662 (13%), Positives = 187/662 (28%), Gaps = 111/662 (16%) Query: 23 YSLSGSWRVSNGNG----SLELPATVPGYVHSALHQHGLIQDPYYRFNDL-----NYRWI 73 LSG W NG + + Y + +Y W+ Sbjct: 37 SDLSGVWDFKLDNGKGFEEKWYEKPLKDA---DTMP---VPASYNDLKEGTDFRDHYGWV 90 Query: 74 SLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNV 133 Y +P + Q++ L V A I N I + F + ++ + Sbjct: 91 -----FYQRNISVP-EYVKSQRIVLRCAAVTHYAMIYLNGKLICEHKGGFLPFEVELNDD 144 Query: 134 VK-DVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDW 192 ++ N L + + + Y + + K Q + ++D+ Sbjct: 145 LQDGDNLLTIAVNNVIDYTTLPVGGKANMMSGMMGGMGAGASD-------KPQNNPNFDF 197 Query: 193 GPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVT 252 F GI + V+I +++ +T D + + + + ++ Sbjct: 198 ---FNYCGITRPVKIYTTPETYINDITVTADIDFTKEEPSAVLNYNVEIKGKDYNNITCK 254 Query: 253 VAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGG 312 V + + + ++ E E V++ + + + + Q Y + Sbjct: 255 VELFDEEGTKLSETE-GSEGTFEISNVRLWQPLNAYLYKIKVTAGQDVYTLP-------- 305 Query: 313 LKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRL 372 R+V++ F IN P + KG + + + Sbjct: 306 --------YGVRSVRVD----------GTKFLINEKPFYFKGYGKHEDTFPNGRGINLPM 347 Query: 373 QL-LFQSVVDANMNTLRVWGGGIYE-QDEFYALCDELGIMVWQD-------FMFASALYP 423 + + N+ R Y +E LCDE GI+V + F Sbjct: 348 NTKDISIMKWQHANSFRT---SHYPYSEEMMRLCDEEGIVVIDETTAVGVNLQFGGGANF 404 Query: 424 TEP-----------GFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPR 472 + + + R K+H +++WS NE + A + + P Sbjct: 405 GGERIGTFDKEHGVQTQEHHKDVIRDLISRDKNHACVVMWSIANEPDSAAEGAYDYFKPL 464 Query: 473 -DMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMK---TMEEGWISYDPYSIQY 528 D+ +D ++S + S GW P ++ Sbjct: 465 YDLARELDPQKR------PCTLVSVQGTTADTDCSSQLSDVICLNRYYGWYFGGP-DLEV 517 Query: 529 GDIHFYNYADDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHH 588 +I + +W K + +EYG + V E++ ++ Sbjct: 518 SEI---GLRKELSDWGKLGKPVMFTEYGADTVSGLHDTTSVMYTEEYQVEYYEMNNKV-- 572 Query: 589 EDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGK 648 + F + + F D +++ Q K F + ++V Sbjct: 573 ---------FDEFDFVVGEQA---WNFADFATSQSLLRVQGNKKGL-FTRDRKPKMVAHY 619 Query: 649 GH 650 Sbjct: 620 FR 621 >4XZW-A nrPDB Length = 313 Score = 44.5 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 38/234 (16%), Positives = 65/234 (27%), Gaps = 47/234 (20%) Query: 346 NGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVW------GGGIYEQDE 399 +G P L+G + F D Q L N +R+ G Q E Sbjct: 23 DGKPFQLRGISTHGLQWFGQFANKDAFQTLRDDWK---ANVVRLAMYTDPNANGYIAQPE 79 Query: 400 FY--------ALCDELGIMVWQDFMFASALYPTEPG-FLASVRKEVTYQVRRLKSHPSII 450 + ELG+ V + L +P + ++ R + P++I Sbjct: 80 WLKAKVKEGVEAAKELGMYV---IIDWHILNDNDPNLYKEQAKRFFAEMAREYGNTPNVI 136 Query: 451 IWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNG 510 NE + P Y + + + S D+ I G Sbjct: 137 Y-EIANE-PNGDVTWEEKIRP-------------YADEVIRTIRSIDRDNLIIV---GTG 178 Query: 511 MKTMEEGWISYDPYSIQ--------YGDIHFYNYADDCWNWKIFPKARLVSEYG 556 + + ++ DP + Y H D V+E+G Sbjct: 179 TWSQDVDDVASDPLPYKNIMYALHFYAGTHGQFLRDKANYALSKGTPIFVTEWG 232 >4UOQ-A nrPDB Length = 695 Score = 39.5 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 36/107 (33%), Gaps = 15/107 (14%) Query: 405 DELGIMVWQDFMFASALY-PTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALS 463 DE G ++W A + PT P F + K +P+I+ W NE Sbjct: 114 DEQGHVIW---PGARQHWRPTSPTFRTYALRLCREMAEHYKDNPAIVSWHVGNEYGCHNY 170 Query: 464 VNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNG 510 + Y DD V + + R + DK ++ + Sbjct: 171 FD-----------YSDDAVQAFREWCRDRYGTIDKVNAAWGTNFWSQ 206 >4CT9-A nrPDB Length = 394 Score = 38.0 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 42/261 (16%), Positives = 88/261 (33%), Gaps = 19/261 (7%) Query: 144 FRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWK 203 F A A ++ + R+P +G ++RK GP + +W+ Sbjct: 103 FFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQ 162 Query: 204 DVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQT 263 +V + + Y + ++ +E V + V + Sbjct: 163 EV-LPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEE-------VEVGTYPKVHG 214 Query: 264 NDIEL-QQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVY 322 ++ + +E R+ +L +I+K + E W G G T G + + Sbjct: 215 VEVVVRGREDRVAELAERIKKKLLKEVW---GEGEMTLAEAVKRRMEREGATLSTMESL- 270 Query: 323 FRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNW---IPADSFQDKVTSDRLQLLFQSV 379 T L+ I PG S F + G+ + G+ +P D V+++ + + ++ Sbjct: 271 --TGGLLGAEITRVPGAS-RFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAA 327 Query: 380 VDANMNTLRVWGGGIYEQDEF 400 +T + G+ D Sbjct: 328 RSLFGSTYALATTGVAGPDPL 348 >4NRS-A nrPDB Length = 449 Score = 38.0 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 347 GLPIFLKGSNWIPADSFQDKV----TSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYA 402 G P ++G+N+ + R++L + + + +N LRV D+ Y Sbjct: 52 GEPYLIRGANYWQGMNLGADDCSGGDRKRMELEIKQMAEMGINNLRVMASSEGPDDQPYR 111 Query: 403 L 403 + Sbjct: 112 M 112 >5GSM-A nrPDB Length = 786 Score = 36.1 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 42/125 (33%), Gaps = 25/125 (20%) Query: 342 YFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVW----------- 390 + I+G P+ + G +V +D + + +A +NT+ + Sbjct: 10 RYVIDGEPVTIAGGTLQ-----FFRVPADAWKDRLLKMREAGLNTVDTYVAWNWHEPEKG 64 Query: 391 -----GGGIYEQD--EFYALCDELGIMV-WQDFMFASALYPTEPGFLASVRKEVTYQVRR 442 G +++ F L DELG V + + + G + E + + Sbjct: 65 SFDFKGETHPQRNLVGFLELADELGFYVIIRPGPYICGEWRNG-GIPDWLIDEHPEILAK 123 Query: 443 LKSHP 447 + P Sbjct: 124 GPNGP 128 >5WH8-A nrPDB Length = 323 Score = 35.7 bits (80), Expect = 0.096, Method: Composition-based stats. Identities = 45/232 (19%), Positives = 70/232 (30%), Gaps = 40/232 (17%) Query: 347 GLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRV------WGGGIYEQ--- 397 G P+ L+G + F T L L V D N++ R+ WGG Q Sbjct: 26 GKPVQLRGMSSHGLAWFPKCYTEASLTAL---VKDWNIDIFRLAIYTHEWGGYTTNQWKS 82 Query: 398 --------DEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSI 449 D +C +LGI D+ + L Y + K + Sbjct: 83 KDDYNAYIDNMVDICAKLGIYCIIDWHVLNDGSGDPNYTLDDAIPFWDYMSAKHKDDKHV 142 Query: 450 IIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPT- 508 ++ NE V W V Y + + ++ D + I +PT Sbjct: 143 -LYEICNE-PNGFDVKWADVKE-------------YAEAVIPVIRKNDPDKIIICGTPTW 187 Query: 509 -NGMKTMEEGWISYDPYSIQ---YGDIHFYNYADDCWNWKIFPKARLVSEYG 556 + + +SYD Y H D A V+E+G Sbjct: 188 SQDVDLAAQDPLSYDNVMYTLHFYSGTHTQYLRDKAQVAINKGLALFVTEFG 239 >3TTS-A nrPDB Length = 675 Score = 35.3 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 15/35 (42%) Query: 423 PTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNE 457 P P + + R K HP I++W +NE Sbjct: 116 PNSPTYRKYAKILAGKLAERYKDHPQIVMWHVSNE 150 >2VRK-A nrPDB Length = 496 Score = 34.5 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 31/208 (14%), Positives = 55/208 (26%), Gaps = 22/208 (10%) Query: 355 SNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQD 414 + D + R+ N + V + EF LC+ LG + Sbjct: 77 DEYHWKDGVGPREKRKRM---------VNTHWGGVIENNHFGTHEFMMLCELLGCEPYIS 127 Query: 415 FMFASALYPTEPGFLASV-----RKEVTYQVRRLKSHP-SIIIWSGNNENEVALSVNWFH 468 S ++ + ++ + P I W NEN N Sbjct: 128 GNVGSGTVQEMSEWVEYITFDGESPMANWRRENGREKPWRIKYWGVGNEN-WGCGGNMRA 186 Query: 469 VNPRDMKTYIDDYVTLYVKN-IRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSI- 526 D+ Y+ Y N + KI + + + +S Y++ Sbjct: 187 EYYADLYRQFQTYLRNYGDNKLHKIACGANTADYHW-TEVLMKQAAPFMHGLSLHYYTVP 245 Query: 527 --QYGDIHFYNYADDCWNWKIFPKARLV 552 + D W W KA + Sbjct: 246 GPWEKKGPATGFTTDEW-WVTLKKALFM 272 >3WH9-A nrPDB Length = 345 Score = 33.8 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 47/147 (31%), Gaps = 11/147 (7%) Query: 424 TEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNE-----NEVALSVNWFHVNPRDMKTYI 478 T ++ + + V R + ++ W NE + ++ NW + +K Sbjct: 135 TSDTMQSAYQTYIKTVVERYSNSSAVFAWELANEPRCPSCDTSVLYNWIEKTSKFIKGLD 194 Query: 479 DDYVTLYVKNIRKIVLSEDKSRPFIASS---PTNGMKTMEEGWISYDPYSIQYGDIHFYN 535 D + + + D S P+ S T + + + Y +G + Sbjct: 195 ADRMVCIGDEGFGLNIDSDGSYPYQFSEGLNFTMNLDIDTIDFGTLHLYPDSWGTSDDWG 254 Query: 536 YADDCWNW---KIFPKARLVSEYGYQS 559 + K K L+ EYG S Sbjct: 255 NGWITAHGAACKAAGKPCLLEEYGVTS 281 >4UCF-A nrPDB Length = 689 Score = 33.8 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 43/151 (28%), Gaps = 25/151 (16%) Query: 405 DELGIMVWQDFMFASALY-PTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALS 463 DE G VW A + PT P F K +P ++ W +NE Sbjct: 111 DERGDTVW---PGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYG---C 164 Query: 464 VNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDP 523 N F DY ++ +K K+ + + S Sbjct: 165 HNRF------------DYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEII 212 Query: 524 YSIQYGDIHFYNYADDCWNWKIFPKARLVSE 554 GD +F N K+ R S+ Sbjct: 213 PPRYIGDGNFMN------PGKLLDYKRFSSD 237 >3SMA-A nrPDB Length = 286 Score = 33.0 bits (73), Expect = 0.66, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 24/91 (26%) Query: 230 AWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVET 289 + + AS G Q V Q + + + + R+ E Sbjct: 39 GGVLLVHASLSALGWVCGGAQAVVLALQDAVGKEGTLVMPTFSGDLSDPSTWRRPPVPED 98 Query: 290 WWPRGHGNQTGYNMTILFALDGGLKIEKAAK 320 WWP ++ + G E + Sbjct: 99 WWPVIREQMPPFDPDLTPTRGMGAVAECFRR 129 >3JUG-A nrPDB Length = 345 Score = 33.0 bits (73), Expect = 0.67, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 36/104 (34%), Gaps = 19/104 (18%) Query: 346 NGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLR--VWGGGIYEQD----- 398 NG P +KG N D ++ + NT+R + GG +E+D Sbjct: 36 NGQPFVMKGINH------GHAWYKDTASTAIPAIAEQGANTIRIVLSDGGQWEKDDIDTV 89 Query: 399 -EFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR 441 E L ++ ++ + T + + + V Y + Sbjct: 90 REVIELAEQNKMVAVVEV-----HDATGRDSRSDLDRAVDYWIE 128 >5E9A-A nrPDB Length = 712 Score = 32.6 bits (72), Expect = 0.72, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%) Query: 424 TEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNE 457 + P + V+ +R HP++I W +NE Sbjct: 149 SSPVYREKVQLMNGQLAKRYAHHPAVIGWHISNE 182 >3MAN-A nrPDB Length = 302 Score = 31.8 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 32/233 (13%), Positives = 67/233 (28%), Gaps = 36/233 (15%) Query: 343 FKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRV--------WGGGI 394 ++ NG ++G + P + + + T F + NT+RV G Sbjct: 12 YEANGQEFIIRGVS-HPHNWY-PQHTQA-----FADIKSHGANTVRVVLSNGVRWSKNGP 64 Query: 395 YEQDEFYALCDELGIMVWQDFMFASA-LYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWS 453 + +LC + ++ + + + L L+ ++ + Sbjct: 65 SDVANVISLCKQNRLICMLEVHDTTGYGEQSGASTLDQAVDYWIELKSVLQGEEDYVLIN 124 Query: 454 GNNE---NEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNG 510 NE N+ A W ++ L ++ P TN Sbjct: 125 IGNEPYGNDSATVAAWATDTSAAIQ-------RLRAAGFEHTLV---VDAPNWGQDWTNT 174 Query: 511 MKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPK-------ARLVSEYG 556 M+ + + DP IH Y + + ++ E+G Sbjct: 175 MRNNADQVYASDPTGNTVFSIHMYGVYSQASTITSYLEHFVNAGLPLIIGEFG 227 >5XTH-p nrPDB Length = 172 Score = 31.8 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 7/76 (9%) Query: 613 RTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLE 672 + KD TQ+++ + E EF+ R + G Y + D ++ P W + Sbjct: 45 KNEKDMAKATQLLK----EAEEEFWYRQHPQPYIFPDSPGGTSYERY-DCYKVPEWCLDD 99 Query: 673 YGGKWKMLH--YFARR 686 + K ++ YFA+R Sbjct: 100 WHPSEKAMYPDYFAKR 115 >4PSP-A nrPDB Length = 585 Score = 31.8 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 28/186 (15%), Positives = 56/186 (30%), Gaps = 27/186 (14%) Query: 656 YWQLNDIWQAPSWA---SLEYGGKWKMLHYFARRF---------FAPLLPVGFEDEGVFY 703 YWQ +D A SW+ ++Y M+H R +P+ +E + Sbjct: 299 YWQTDDAISASSWSYTVGIKYYSSKAMVHSLLDRVSKNGNMLLNISPMANGVLPEEQIKV 358 Query: 704 VYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNS---SIVVKAGEAVVLF-QMPVSELLK 759 + + D + + W + V + ++ + + F + ++L Sbjct: 359 LNDIGDFL-SRYGEAVYDTRAWDIYGEGPNQVEGGSFTAPLQGNSSDIRFTRNKEDDVLY 417 Query: 760 RCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLEANITV----NISQKGNVF 815 E +VS + L SLK + L + Q + Sbjct: 418 VTVLGWPEDNLVSV------KNLGSNALVDLESLKSVELLGDKAGDYVKVSEWEQSKDAL 471 Query: 816 VFDLET 821 L + Sbjct: 472 DITLPS 477 >2WHL-A nrPDB Length = 294 Score = 31.8 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 36/104 (34%), Gaps = 19/104 (18%) Query: 346 NGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLR--VWGGGIYEQD----- 398 NG P ++G N D ++ + NT+R + GG +E+D Sbjct: 13 NGQPFVMRGINH------GHAWYKDTASTAIPAIAEQGANTIRIVLSDGGQWEKDDIDTI 66 Query: 399 -EFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVR 441 E L ++ ++ + T + + + V Y + Sbjct: 67 REVIELAEQNKMVAVVEV-----HDATGRDSRSDLNRAVDYWIE 105 >6IJO-1 nrPDB Length = 248 Score = 31.1 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 17/48 (35%) Query: 324 RTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDR 371 RT+ +G G NG + +K NW+P + D Sbjct: 26 RTLSARTAAPRGFSGRRVAAVSNGSRVTMKAGNWLPGSDAPAWLPDDL 73 >3WFL-A nrPDB Length = 342 Score = 30.7 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 66/206 (32%), Gaps = 29/206 (14%) Query: 370 DRLQLLFQSVVDAN----MNTLRVWGGGIYEQDEFYALCDELGIMVW-QDFMFASALYPT 424 +RL + S N +N + W D GI + F ++ + T Sbjct: 89 ERLDYVVSSAEQHNVKLIINFVNNWS-------------DYGGIPAYVNAFGGSTTSWYT 135 Query: 425 EPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNE-----NEVALSVNWFHVNPRDMKTYID 479 + A+ R + V R P++ W NE + ++ NW +K+ Sbjct: 136 DEASQAAYRNYIKTVVSRYIDSPAVFAWELANEPRCHGCDTSVIYNWVAATSSFIKSIDS 195 Query: 480 DYVTLYVKNIRKIVLSEDKSRPFIA---SSPTNGMKTMEEGWISYDPYSIQYGDIHFYN- 535 ++ + + D S P+ ++ T + + ++ Y +G + + Sbjct: 196 QHLVCIGDEGLGLDIDSDGSYPYSYYEGTNFTLNLGVDTIDFGTFHLYPSSWGVSNSFGS 255 Query: 536 --YADDCWNWKIFPKARLVSEYGYQS 559 K L EYG S Sbjct: 256 PWVTAHGAACAAAGKPCLFEEYGVTS 281 >3VUP-A nrPDB Length = 351 Score = 30.7 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 55/167 (32%), Gaps = 41/167 (24%) Query: 339 LSFYFKINGLPIFLKGSN-------WIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVW- 390 + +F +NG +FL G N + D + +R++ F+ + DA N++R+W Sbjct: 5 QNGHFVLNGQRVFLSGGNLPWMSYAYDFGDGQWQR-NKNRIEPEFKKLHDAGGNSMRLWI 63 Query: 391 --------------------GGGIYEQD--EFYALCDELGIMV----W------QDFMFA 418 G D + + I+V W Sbjct: 64 HIQGETTPAFNDQGFVTGPDKQGTMLDDMKDLLDTAKKYNILVFPCLWNAAVNQDSHNRL 123 Query: 419 SALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVN 465 L + + + K + V +K H ++ W NE E + + Sbjct: 124 DGLIKDQHKLQSYIDKALKPIVNHVKGHVALGGWDLMNEPEGMMIPD 170 >5BR7-A nrPDB Length = 393 Score = 30.7 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 25/178 (14%), Positives = 51/178 (28%), Gaps = 24/178 (13%) Query: 57 LIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTI 116 LI P Y + R + W + ++P V+ FD FN+ Sbjct: 144 LIGRPLY---EAFIRDYTAKQWQ-TDPKELPAGNITRLPVRYNFD------NRYFNDTYE 193 Query: 117 GKTDNMFTGYSFDITNVVKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGEC 176 G + + + ++ + L + + Q+ E Sbjct: 194 GLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNP-EAPVVYTGPLDRYFDYSEG 252 Query: 177 HVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYL------TFLPVYDNAS 228 H+ + + D+ + G ++ + YN A Y F P ++ Sbjct: 253 HLGWR-------TLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRH 303 >2CSX-A nrPDB Length = 497 Score = 30.3 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 20/147 (13%), Positives = 42/147 (28%), Gaps = 8/147 (5%) Query: 395 YEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSG 454 YE + Y L DE+ + ++ F ++ L + E+ ++ L S Sbjct: 307 YEVVQEYGL-DEVRYFLLREVPFGQDGDFSKKAILNRINGELANEIGNLYSR-------V 358 Query: 455 NNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTM 514 N L + + + Y + K+ + +S N Sbjct: 359 VNMAHKFLGGEVSGARDEEYAKIAQESIKNYENYMEKVNFYKAIEEILKFTSYLNKYVDE 418 Query: 515 EEGWISYDPYSIQYGDIHFYNYADDCW 541 ++ W + Y D + Sbjct: 419 KQPWALNKERKKEELQKVLYALVDGLF 445 >4AWE-A nrPDB Length = 387 Score = 30.3 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 48/159 (30%), Gaps = 27/159 (16%) Query: 426 PGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLY 485 P + ++ V V R + +I+ W NE + PR K + VT + Sbjct: 150 PKIKEAFKRYVKAMVTRYRDSEAILAWELANEARCG--ADGTRNLPRSEKGCTTETVTGW 207 Query: 486 VKNIRKIVLSEDKSRPFI-------------ASSPTNGMKT---------MEEGWISYDP 523 ++ + V S D + NG + + Sbjct: 208 IEEMSAYVKSLDGNHLVTWGGEGGFNRGEDEEDGFYNGADGGDFDRELGLRNVDFGTMHL 267 Query: 524 YSIQYGDIHFYN---YADDCWNWKIFPKARLVSEYGYQS 559 Y + ++ D + + K ++ EYG+ + Sbjct: 268 YPDWWSKSIEWSNQWIHDHAASGRAANKPVVLEEYGWMT 306 >5OGZ-A nrPDB Length = 456 Score = 29.9 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 30/89 (33%), Gaps = 3/89 (3%) Query: 466 WFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYS 525 ++++P Y ++ + LY K ++ ED + +I YDP S Sbjct: 248 RWYLDPVLKGRYPENALKLYKKKGIELSFPEDDLKLISQPIDFIAFNNYSSEFIKYDPSS 307 Query: 526 ---IQYGDIHFYNYADDCWNWKIFPKARL 551 + + W I+P+ Sbjct: 308 ESGFSPANSILEKFEKTDMGWIIYPEGLY 336 >6NMI-A nrPDB Length = 653 Score = 29.5 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 3/119 (2%) Query: 275 VKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIK 334 ++ I K E W P + Y + + + FR Q + + + Sbjct: 419 LQNNGYIAKVQCAEVWCPM---SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHE 475 Query: 335 GSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGG 393 F N + + +R+Q+L + +NT+ + G Sbjct: 476 RRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVG 534 >5OF4-A nrPDB Length = 553 Score = 29.5 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 3/119 (2%) Query: 275 VKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIK 334 ++ I K E W P + Y + + + FR Q + + + Sbjct: 267 LQNNGYIAKVQCAEVWCPM---SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHE 323 Query: 335 GSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGG 393 F N + + +R+Q+L + +NT+ + G Sbjct: 324 RRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVG 382 >5IY9-V nrPDB Length = 782 Score = 29.5 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 3/119 (2%) Query: 275 VKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIK 334 ++ I K E W P + Y + + + FR Q + + + Sbjct: 496 LQNNGYIAKVQCAEVWCPM---SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHE 552 Query: 335 GSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGG 393 F N + + +R+Q+L + +NT+ + G Sbjct: 553 RRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVG 611 >4ERN-A nrPDB Length = 289 Score = 29.5 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 3/119 (2%) Query: 275 VKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIK 334 ++ I K E W P + Y + + + FR Q + + + Sbjct: 3 LQNNGYIAKVQCAEVWCPM---SPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHE 59 Query: 335 GSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGG 393 F N + + +R+Q+L + +NT+ + G Sbjct: 60 RRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVG 118 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.112 0.280 Lambda K H 0.267 0.0345 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,574,107 Number of Sequences: 36641 Number of extensions: 1063962 Number of successful extensions: 3174 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 61 Number of HSP's successfully gapped in prelim test: 45 Number of HSP's that attempted gapping in prelim test: 2847 Number of HSP's gapped (non-prelim): 155 length of query: 879 length of database: 10,336,785 effective HSP length: 106 effective length of query: 773 effective length of database: 6,452,839 effective search space: 4988044547 effective search space used: 4988044547 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (29.1 bits)