BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8IIK4 (219 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4ADS-G nrPDB 446 e-126 1Q7R-A nrPDB 110 4e-25 4WXY-B nrPDB 109 9e-25 2ISS-D nrPDB 107 3e-24 2NV0-A nrPDB 99 1e-21 2YWJ-A nrPDB 95 2e-20 2YWD-A nrPDB 82 1e-16 3N18-A nrPDB 29 1.6 1L9X-A nrPDB 28 2.3 3FGC-A nrPDB 28 3.4 3RJ4-A nrPDB 28 3.9 1OX5-A nrPDB 28 4.3 3U0E-A nrPDB 27 6.1 2YJV-A nrPDB 27 7.3 1E0Z-A nrPDB 27 7.4 5JK6-A nrPDB 27 9.6 >4ADS-G nrPDB Length = 217 Score = 446 bits (1147), Expect = e-126, Method: Compositional matrix adjust. Identities = 216/217 (99%), Positives = 217/217 (100%) Query: 3 EITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCA 62 EITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCA Sbjct: 1 EITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCA 60 Query: 63 YENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRN 122 YENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRN Sbjct: 61 YENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRN 120 Query: 123 FYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII 182 FYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII Sbjct: 121 FYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII 180 Query: 183 AAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 AAVEQNNCLGTVF+PELLPHTAFQQYFYEKVKNYKYS Sbjct: 181 AAVEQNNCLGTVFNPELLPHTAFQQYFYEKVKNYKYS 217 >1Q7R-A nrPDB Length = 219 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 79/218 (36%), Positives = 104/218 (47%), Gaps = 24/218 (11%) Query: 2 SEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCC 61 S + IGVL LQG H+ ++ + V+ L DGLV+PGGESTT+RR Sbjct: 22 SNMKIGVLGLQGAVREHVR---AIEACGAEAVIVKKSEQLEGLDGLVLPGGESTTMRRLI 78 Query: 62 AYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICR 121 + L L F KP++GTCAG ILL+K + ++ G +DIT+ R Sbjct: 79 --DRYGLMEPLKQFAAA-GKPMFGTCAGLILLAKRIVGY-------DEPHLGLMDITVER 128 Query: 122 NFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNI 181 N +G Q +SF L+I F IRAP+I E D V VLAT++ + Sbjct: 129 NSFGRQRESFEAELSIKGVGDGF----VGVFIRAPHIVEA-GDGVDVLATYN------DR 177 Query: 182 IAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 I A Q LG FHPEL QYF VK K + Sbjct: 178 IVAARQGQFLGCSFHPELTDDHRLMQYFLNMVKEAKMA 215 >4WXY-B nrPDB Length = 228 Score = 109 bits (272), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 78/219 (35%), Positives = 105/219 (47%), Gaps = 24/219 (10%) Query: 1 MSEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRC 60 M+ + IGVL LQG H+ ++ + V+ L DGLV+PGGESTT+RR Sbjct: 30 MASMKIGVLGLQGAVREHVR---AIEACGAEAVIVKKSEQLEGLDGLVLPGGESTTMRRL 86 Query: 61 CAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITIC 120 + L L F KP++GTCAG ILL+K + ++ G +DIT+ Sbjct: 87 I--DRYGLMEPLKQFAAA-GKPMFGTCAGLILLAKRIVGY-------DEPHLGLMDITVE 136 Query: 121 RNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPN 180 RN +G Q +SF L+I F IRAP+I E D V VLAT++ + Sbjct: 137 RNSFGRQRESFEAELSIKGVGDGF----VGVFIRAPHIVEA-GDGVDVLATYN------D 185 Query: 181 IIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 I A Q LG F+PEL QYF VK K + Sbjct: 186 RIVAARQGQFLGCSFNPELTDDHRLMQYFLNMVKEAKMA 224 >2ISS-D nrPDB Length = 208 Score = 107 bits (268), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/213 (37%), Positives = 110/213 (51%), Gaps = 23/213 (10%) Query: 2 SEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCC 61 S + IGVL +QGD H+ KL + +L V+ L + DGL++PGGESTT+ R Sbjct: 19 SHMKIGVLGVQGDVREHVEALHKLGVETL---IVKLPEQLDMVDGLILPGGESTTMIRIL 75 Query: 62 AYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICR 121 E D + LV I+ P++ TCAG ILL+K ++N YS + G LDIT+ R Sbjct: 76 K-EMD-MDEKLVERINN-GLPVFATCAGVILLAKRIKN---YS----QEKLGVLDITVER 125 Query: 122 NFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNI 181 N YG Q +SF + I + K A IRAP I E V++LAT+ ++ Sbjct: 126 NAYGRQVESFETFVEI---PAVGKDPFRAIFIRAPRIVET-GKNVEILATYDYDP----- 176 Query: 182 IAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVK 214 V++ N L FHPEL +YF E VK Sbjct: 177 -VLVKEGNILACTFHPELTDDLRLHRYFLEMVK 208 >2NV0-A nrPDB Length = 196 Score = 99.0 bits (245), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 73/214 (34%), Positives = 101/214 (47%), Gaps = 24/214 (11%) Query: 4 ITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAY 63 +TIGVL LQG HI+ ++ + V+ L DGL++PGGESTT+RR Sbjct: 2 LTIGVLGLQGAVREHIH---AIEACGAAGLVVKRPEQLNEVDGLILPGGESTTMRRLI-- 56 Query: 64 ENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNF 123 + L F KP++GTCAG I+L+K + + G L++ + RN Sbjct: 57 DTYQFMEPLREFA-AQGKPMFGTCAGLIILAKEIAG-------SDNPHLGLLNVVVERNS 108 Query: 124 YGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIA 183 +G Q DSF L I + T IRAP+I E + V+VL+ + I Sbjct: 109 FGRQVDSFEADLTI----KGLDEPFTGVFIRAPHILEA-GENVEVLSEHNGR------IV 157 Query: 184 AVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYK 217 A +Q LG FHPEL Q F E V+ YK Sbjct: 158 AAKQGQFLGCSFHPELTEDHRVTQLFVEMVEEYK 191 >2YWJ-A nrPDB Length = 186 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 72/210 (34%), Positives = 96/210 (45%), Gaps = 35/210 (16%) Query: 4 ITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAY 63 + IGVL++QGD E H K +V+ V DL D L+IPGGEST + + Sbjct: 1 MIIGVLAIQGDVEEHEEAIKK---AGYEAKKVKRVEDLEGIDALIIPGGESTAIGKLMK- 56 Query: 64 ENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNF 123 L+ I PI GTCAG +LLSK N+ +DIT+ RN Sbjct: 57 -----KYGLLEKIKNSNLPILGTCAGMVLLSKGTGI--------NQILLELMDITVKRNA 103 Query: 124 YGSQNDSFICSLNIISDSSAFKKDLT---AACIRAPYIREILSDEVKVLATFSHESYGPN 180 YG Q DSF + KDL IRAP + +ILSD+V+V+A + Sbjct: 104 YGRQVDSFEKEIEF--------KDLGKVYGVFIRAPVVDKILSDDVEVIARDGDK----- 150 Query: 181 IIAAVEQNNCLGTVFHPELLPHTAFQQYFY 210 I V+Q + FHPE L ++ Y Y Sbjct: 151 -IVGVKQGKYMALSFHPE-LSEDGYKVYKY 178 >2YWD-A nrPDB Length = 191 Score = 82.4 bits (202), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 61/207 (29%), Positives = 91/207 (43%), Gaps = 23/207 (11%) Query: 5 TIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYE 64 +GVL+LQGDF H +L I + +VR L L++PGGESTT+ + Sbjct: 4 VVGVLALQGDFREHKEALKRLGIEA---KEVRKKEHLEGLKALIVPGGESTTIGKLA--R 58 Query: 65 NDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFY 124 + + + + ++GTCAG I L+K + + + G L+ + RN + Sbjct: 59 EYGIEDEVRKRVEEGSLALFGTCAGAIWLAKEI------VGYPEQPRLGVLEAWVERNAF 112 Query: 125 GSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAA 184 G Q +SF L + S IRAP R L + V+VLA ++ Sbjct: 113 GRQVESFEEDLEVEGLGS-----FHGVFIRAPVFRR-LGEGVEVLARLG------DLPVL 160 Query: 185 VEQNNCLGTVFHPELLPHTAFQQYFYE 211 V Q L + FHPEL +YF E Sbjct: 161 VRQGKVLASSFHPELTEDPRLHRYFLE 187 >3N18-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 6/86 (6%) Query: 51 GGESTTVRRCCAYENDTLYNALVHFIHVLKKPI---WGTCAGCILLSKNVENIKLYSNFG 107 GG+ +TV Y D + + + ++ K + G G +LL N + ++ Sbjct: 43 GGDRSTVEFSPVYGTDADFKSDISYLKSKGKKVVLSIGGQNGVVLLPDNAAKDRFINSIQ 102 Query: 108 ---NKFSFGGLDITICRNFYGSQNDS 130 +K+ F G+DI + Y + ND+ Sbjct: 103 SLIDKYGFDGIDIDLGSGIYLNGNDT 128 >1L9X-A nrPDB Length = 315 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 39/172 (22%), Positives = 67/172 (38%), Gaps = 26/172 (15%) Query: 45 DGLVIPGGESTTVRRCCAYENDTLYN-ALVHFIHVLKKPIWGTCAG-----------CIL 92 +G++ PGG R A YN ++ F P+WGTC G C+L Sbjct: 88 NGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLL 147 Query: 93 LSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAAC 152 + + ++ + NF G L + +NF + SL + ++ F K + Sbjct: 148 TATDTVDVAMPLNFTG----GQLHSRMFQNF----PTELLLSLAVEPLTANFHK--WSLS 197 Query: 153 IRAPYIREILSDEVKVLATFSHESYGPNIIAAVE--QNNCLGTVFHPELLPH 202 ++ + E L VL T + I+ +E + G +HPE P+ Sbjct: 198 VKNFTMNEKLKKFFNVLTTNTDGKI--EFISTMEGYKYPVYGVQWHPEKAPY 247 >3FGC-A nrPDB Length = 355 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 119 ICRNFYGSQNDSFICSLNIISDSSAFK 145 ICRNF G DS++ + I DS K Sbjct: 242 ICRNFLGHWYDSYVNATKIFDDSDQTK 268 >3RJ4-A nrPDB Length = 290 Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust. Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 15 FEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVI 49 F+ ++N + + + S + +Q R VHDL C G + Sbjct: 101 FKLYLNSYNQTRFASWDEVQTRLVHDLSACAGETV 135 >1OX5-A nrPDB Length = 555 Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 5/50 (10%) Query: 150 AACIRAPYIREILSDEVKVL-ATFSHESYGPNIIAAVEQNNCLGTVFHPE 198 AA + + + + +D K+ A + E + IAAV +NN T FHPE Sbjct: 153 AAILNSEKKKNLENDGWKIAKAKYGSEEF----IAAVNKNNIFATQFHPE 198 >3U0E-A nrPDB Length = 428 Score = 26.9 bits (58), Expect = 6.1, Method: Compositional matrix adjust. Identities = 10/33 (30%), Positives = 19/33 (57%) Query: 92 LLSKNVENIKLYSNFGNKFSFGGLDITICRNFY 124 ++ K ++N++L + N F FGG + T+ Y Sbjct: 394 IVRKRIDNVQLNTVLSNSFGFGGTNATLVFQRY 426 >2YJV-A nrPDB Length = 161 Score = 26.9 bits (58), Expect = 7.3, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 90 CILLSKNVENIK-LYSNFGNKFSFGGLDITI 119 C + ++V ++ L+SNFG + SFGG IT+ Sbjct: 9 CDIYQEDVNVVEPLFSNFGGRASFGGQIITV 39 >1E0Z-A nrPDB Length = 128 Score = 26.9 bits (58), Expect = 7.4, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 23/47 (48%), Gaps = 5/47 (10%) Query: 136 NIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII 182 I+SD +KD+ CI +P +DEVK++ H Y N + Sbjct: 86 QILSDEEVEEKDVRLTCIGSP-----AADEVKIVYNAKHLDYLQNRV 127 >5JK6-A nrPDB Length = 438 Score = 26.6 bits (57), Expect = 9.6, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 156 PYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFH--PELLPHTAFQQYFY 210 P RE + K+ +T+ H P I E+ G V++ EL P A Q+ Y Sbjct: 163 PVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAY 219 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4ADS-G nrPDB 337 2e-93 1Q7R-A nrPDB 258 1e-69 4WXY-B nrPDB 255 8e-69 2NV0-A nrPDB 244 2e-65 2ISS-D nrPDB 236 4e-63 2YWD-A nrPDB 224 2e-59 2YWJ-A nrPDB 206 7e-54 Sequences not found previously or not previously below threshold: 1KA9-H nrPDB 41 3e-04 1GPM-A nrPDB 41 4e-04 1OX5-A nrPDB 41 5e-04 2W7T-A nrPDB 39 0.002 5U6R-A nrPDB 39 0.002 3FIJ-A nrPDB 39 0.002 4GUD-A nrPDB 38 0.003 4WIN-A nrPDB 34 0.050 4WIM-A nrPDB 34 0.057 1L9X-A nrPDB 34 0.071 1K9V-F nrPDB 33 0.095 5TW7-A nrPDB 33 0.12 4OFW-A nrPDB 33 0.12 3TQI-A nrPDB 32 0.16 2VXO-A nrPDB 32 0.19 2A9V-A nrPDB 32 0.21 5IVA-B nrPDB 32 0.25 2VPI-A nrPDB 32 0.26 4L6H-A nrPDB 31 0.48 4YDS-A nrPDB 30 0.75 2N8X-A nrPDB 30 0.76 3EBK-A nrPDB 30 1.0 2VKT-A nrPDB 29 1.3 2VRN-A nrPDB 29 1.3 1WL8-A nrPDB 29 1.4 1OI4-A nrPDB 29 1.9 1YKW-A nrPDB 29 2.5 2VDJ-A nrPDB 28 2.7 5X9W-A nrPDB 28 3.3 2YWB-A nrPDB 28 3.5 1GVH-A nrPDB 27 4.3 1G2I-A nrPDB 27 4.4 4HI0-E nrPDB 27 6.3 >4ADS-G nrPDB Length = 217 Score = 337 bits (864), Expect = 2e-93, Method: Composition-based stats. Identities = 216/217 (99%), Positives = 217/217 (100%) Query: 3 EITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCA 62 EITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCA Sbjct: 1 EITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCA 60 Query: 63 YENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRN 122 YENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRN Sbjct: 61 YENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRN 120 Query: 123 FYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII 182 FYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII Sbjct: 121 FYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNII 180 Query: 183 AAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 AAVEQNNCLGTVF+PELLPHTAFQQYFYEKVKNYKYS Sbjct: 181 AAVEQNNCLGTVFNPELLPHTAFQQYFYEKVKNYKYS 217 >1Q7R-A nrPDB Length = 219 Score = 258 bits (660), Expect = 1e-69, Method: Composition-based stats. Identities = 78/218 (35%), Positives = 103/218 (47%), Gaps = 24/218 (11%) Query: 2 SEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCC 61 S + IGVL LQG H+ ++ + V+ L DGLV+PGGESTT+RR Sbjct: 22 SNMKIGVLGLQGAVREHVRA---IEACGAEAVIVKKSEQLEGLDGLVLPGGESTTMRRLI 78 Query: 62 AYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICR 121 + L L F KP++GTCAG ILL+K + ++ G +DIT+ R Sbjct: 79 --DRYGLMEPLKQFAAA-GKPMFGTCAGLILLAKRIVGY-------DEPHLGLMDITVER 128 Query: 122 NFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNI 181 N +G Q +SF L+I IRAP+I E D V VLAT++ + Sbjct: 129 NSFGRQRESFEAELSIKGVGDG----FVGVFIRAPHIVEA-GDGVDVLATYN------DR 177 Query: 182 IAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 I A Q LG FHPEL QYF VK K + Sbjct: 178 IVAARQGQFLGCSFHPELTDDHRLMQYFLNMVKEAKMA 215 >4WXY-B nrPDB Length = 228 Score = 255 bits (652), Expect = 8e-69, Method: Composition-based stats. Identities = 77/219 (35%), Positives = 104/219 (47%), Gaps = 24/219 (10%) Query: 1 MSEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRC 60 M+ + IGVL LQG H+ ++ + V+ L DGLV+PGGESTT+RR Sbjct: 30 MASMKIGVLGLQGAVREHVRA---IEACGAEAVIVKKSEQLEGLDGLVLPGGESTTMRRL 86 Query: 61 CAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITIC 120 + L L F KP++GTCAG ILL+K + ++ G +DIT+ Sbjct: 87 I--DRYGLMEPLKQFAAA-GKPMFGTCAGLILLAKRIVGY-------DEPHLGLMDITVE 136 Query: 121 RNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPN 180 RN +G Q +SF L+I IRAP+I E D V VLAT++ + Sbjct: 137 RNSFGRQRESFEAELSIKGVGDG----FVGVFIRAPHIVEA-GDGVDVLATYN------D 185 Query: 181 IIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 I A Q LG F+PEL QYF VK K + Sbjct: 186 RIVAARQGQFLGCSFNPELTDDHRLMQYFLNMVKEAKMA 224 >2NV0-A nrPDB Length = 196 Score = 244 bits (623), Expect = 2e-65, Method: Composition-based stats. Identities = 73/214 (34%), Positives = 101/214 (47%), Gaps = 24/214 (11%) Query: 4 ITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAY 63 +TIGVL LQG HI+ ++ + V+ L DGL++PGGESTT+RR Sbjct: 2 LTIGVLGLQGAVREHIHA---IEACGAAGLVVKRPEQLNEVDGLILPGGESTTMRRLI-- 56 Query: 64 ENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNF 123 + L F KP++GTCAG I+L+K + + G L++ + RN Sbjct: 57 DTYQFMEPLREFA-AQGKPMFGTCAGLIILAKEIAG-------SDNPHLGLLNVVVERNS 108 Query: 124 YGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIA 183 +G Q DSF L I + T IRAP+I E + V+VL+ + I Sbjct: 109 FGRQVDSFEADLTIKG----LDEPFTGVFIRAPHILEA-GENVEVLSEHNGR------IV 157 Query: 184 AVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYK 217 A +Q LG FHPEL Q F E V+ YK Sbjct: 158 AAKQGQFLGCSFHPELTEDHRVTQLFVEMVEEYK 191 >2ISS-D nrPDB Length = 208 Score = 236 bits (603), Expect = 4e-63, Method: Composition-based stats. Identities = 76/213 (35%), Positives = 107/213 (50%), Gaps = 23/213 (10%) Query: 2 SEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCC 61 S + IGVL +QGD H+ KL + +L V+ L + DGL++PGGESTT+ R Sbjct: 19 SHMKIGVLGVQGDVREHVEALHKLGVETL---IVKLPEQLDMVDGLILPGGESTTMIRIL 75 Query: 62 AYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICR 121 + LV I+ P++ TCAG ILL+K ++N ++ G LDIT+ R Sbjct: 76 K--EMDMDEKLVERINN-GLPVFATCAGVILLAKRIKNY-------SQEKLGVLDITVER 125 Query: 122 NFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNI 181 N YG Q +SF + I + K A IRAP I E V++LAT+ ++ Sbjct: 126 NAYGRQVESFETFVEI---PAVGKDPFRAIFIRAPRIVET-GKNVEILATYDYDP----- 176 Query: 182 IAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVK 214 V++ N L FHPEL +YF E VK Sbjct: 177 -VLVKEGNILACTFHPELTDDLRLHRYFLEMVK 208 >2YWD-A nrPDB Length = 191 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 61/208 (29%), Positives = 90/208 (43%), Gaps = 23/208 (11%) Query: 5 TIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYE 64 +GVL+LQGDF H +L I +VR L L++PGGESTT+ + Sbjct: 4 VVGVLALQGDFREHKEALKRLGI---EAKEVRKKEHLEGLKALIVPGGESTTIGKLA--R 58 Query: 65 NDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFY 124 + + + + ++GTCAG I L+K + + + G L+ + RN + Sbjct: 59 EYGIEDEVRKRVEEGSLALFGTCAGAIWLAKEIVG------YPEQPRLGVLEAWVERNAF 112 Query: 125 GSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAA 184 G Q +SF L + S IRAP R L + V+VLA ++ Sbjct: 113 GRQVESFEEDLEVEGLGS-----FHGVFIRAPVFRR-LGEGVEVLARLG------DLPVL 160 Query: 185 VEQNNCLGTVFHPELLPHTAFQQYFYEK 212 V Q L + FHPEL +YF E Sbjct: 161 VRQGKVLASSFHPELTEDPRLHRYFLEL 188 >2YWJ-A nrPDB Length = 186 Score = 206 bits (523), Expect = 7e-54, Method: Composition-based stats. Identities = 70/209 (33%), Positives = 94/209 (44%), Gaps = 29/209 (13%) Query: 4 ITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAY 63 + IGVL++QGD E H K +V+ V DL D L+IPGGEST + + Sbjct: 1 MIIGVLAIQGDVEEHEEAIKK---AGYEAKKVKRVEDLEGIDALIIPGGESTAIGKLMK- 56 Query: 64 ENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNF 123 L+ I PI GTCAG +LLSK N+ +DIT+ RN Sbjct: 57 -----KYGLLEKIKNSNLPILGTCAGMVLLSKGTGI--------NQILLELMDITVKRNA 103 Query: 124 YGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIA 183 YG Q DSF + + IRAP + +ILSD+V+V+A + I Sbjct: 104 YGRQVDSFEKEIEFKDLGKVY-----GVFIRAPVVDKILSDDVEVIARDGDK------IV 152 Query: 184 AVEQNNCLGTVFHPELLPH-TAFQQYFYE 211 V+Q + FHPEL +YF E Sbjct: 153 GVKQGKYMALSFHPELSEDGYKVYKYFVE 181 >1KA9-H nrPDB Length = 200 Score = 41.3 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 56/197 (28%), Gaps = 19/197 (9%) Query: 21 HFIKLQIPSLNIIQVRNVHDLGLCDGLVIPG-GESTTVRRCCAYENDTLYNALVHFIHVL 79 L+ ++ ++ D LV+PG G V R A++ + + Sbjct: 18 AAKALEAAGFSVAVAQDPKAHEEADLLVLPGQGHFGQVMR--AFQESGFVERVRRHLE-R 74 Query: 80 KKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIIS 139 P G C G +L + E G + + R G +L Sbjct: 75 GLPFLGICVGMQVLYEGSEEAPGVRG------LGLVPGEVRRFRAGRVPQMGWNALEFGG 128 Query: 140 DSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPEL 199 + LT R Y + + E G A + + N L FHPE Sbjct: 129 AFA----PLTG---RHFYFANSYYGPLTPYSLGKGEYEGTPFTALLAKENLLAPQFHPEK 181 Query: 200 LPHTAFQQYFYEKVKNY 216 F + Y Sbjct: 182 SGKAGLA--FLALARRY 196 >1GPM-A nrPDB Length = 525 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 61/175 (34%), Gaps = 32/175 (18%) Query: 46 GLVIPGG-ESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYS 104 G+++ GG ESTT E ++ ++ P++G C G ++ + S Sbjct: 53 GIILSGGPESTT-------EENSPRAP--QYVFEAGVPVFGVCYGMQTMAMQLGGHVEAS 103 Query: 105 NFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFK---KDLTAACI-RAPYIRE 160 N R F +Q + S + A K L + + Sbjct: 104 N--------------EREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTA 149 Query: 161 ILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKN 215 I SD + V +T S P I A E+ G FHPE+ + V++ Sbjct: 150 IPSDFITVASTES----CPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRD 200 >1OX5-A nrPDB Length = 555 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 38/183 (20%), Positives = 64/183 (34%), Gaps = 15/183 (8%) Query: 24 KLQIPSLNIIQVRNVHDLG--LCDGLVIPGGESTTVRRCCAYE-NDTLYNALVHFIHVLK 80 ++ + V++ D L++PG N + +I Sbjct: 23 AIEHLGYEVQLVKSPKDFNISGTSRLILPG--VGNYGHFVDNLFNRGFEKPIREYIE-SG 79 Query: 81 KPIWGTCAGC-ILLSKNVENIKLYSNFGNKFSFGGLDIT---ICRNFYGSQNDSFICSLN 136 KPI G C G L + +VE+ K F D + + + S S Sbjct: 80 KPIMGICVGLQALFAGSVESPKSTGLNYIDFKLSRFDDSEKPVPEIGWNSCIPSENLFFG 139 Query: 137 IISDSSAFKKDLTAACIRAPYIREILSDEVKVL-ATFSHESYGPNIIAAVEQNNCLGTVF 195 + + AA + + + + +D K+ A + E + IAAV +NN T F Sbjct: 140 LDPYKRYYFVHSFAAILNSEKKKNLENDGWKIAKAKYGSEEF----IAAVNKNNIFATQF 195 Query: 196 HPE 198 HPE Sbjct: 196 HPE 198 >2W7T-A nrPDB Length = 273 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 45/218 (20%), Positives = 74/218 (33%), Gaps = 37/218 (16%) Query: 9 LSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPG--GESTTVRRCCAYEND 66 ++LQ I + ++ N + R L CDG+ +PG G +C A Sbjct: 37 IALQ--VRLDILYVDSEELEGPNADEARKA--LLGCDGIFVPGGFGNRGVDGKCAAA--- 89 Query: 67 TLYNALVHFIHVLKKPIWGTCAGC----ILLSKNVENIKLYSN--FGNKFSFGGLDITIC 120 + P +G C G I LS+NV ++ F + + + I C Sbjct: 90 -------QVARMNNIPYFGVCLGMQVAVIELSRNVVGWSDANSEEFNKESTHQVVRIMDC 142 Query: 121 -RNFYGSQNDSFICSLNIISDSSAFKKDLTAACI-----------RAPYIREILSDEVKV 168 RN G+ C + I+ SS K + + I Y ++ + + Sbjct: 143 DRNKMGANMHLGACDVYIVEKSSIMAKIYSKSNIVVERHRHRYEVNTAYFEDLRKAGLCI 202 Query: 169 LATFSHESYGPNIIAAVEQNN---CLGTVFHPELLPHT 203 A + AVE + L FHPE + Sbjct: 203 SAVTDPTFSSRCRVEAVENPSLRFFLAVQFHPEFISTP 240 >5U6R-A nrPDB Length = 545 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 38/246 (15%), Positives = 65/246 (26%), Gaps = 51/246 (20%) Query: 1 MSEITIGVLS----LQGDFEPHINHFI----------KLQIPSLNIIQVRNVHDLGLCDG 46 +SE+TIG++ L ++ I +++ ++ R V L D Sbjct: 287 VSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDA 346 Query: 47 LVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGC----ILLSKNVENIK- 101 +++PGG Y F P G C G I +++V N++ Sbjct: 347 ILVPGG--------FGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMEN 398 Query: 102 ----LYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSA-----FKKDLTAAC 152 + + N + S L A L Sbjct: 399 ANSTEFVPDCKYPVVALITEWRDENG-NVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQL 457 Query: 153 IRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNN--------------CLGTVFHPE 198 AP I E +V + + A + + FHPE Sbjct: 458 YNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPE 517 Query: 199 LLPHTA 204 Sbjct: 518 FTSTPR 523 >3FIJ-A nrPDB Length = 254 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 44/198 (22%), Positives = 66/198 (33%), Gaps = 30/198 (15%) Query: 38 VHDLGLCDGLVIPGGESTTVRRCCA----------YENDTLYNALVHFIHVLKKPIWGTC 87 V + L DGL++ GG+ T + D+ ALV KPI+ C Sbjct: 56 VQAISLVDGLLLTGGQDITPQLYLEEPSQEIGAYFPPRDSYEIALVRAALDAGKPIFAIC 115 Query: 88 AGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFI--CSLNIISDSSAFK 145 G L++ + LY + + + GS L + Sbjct: 116 RGMQLVNVALGG-TLYQDISQVETKALQHLQRVDEQLGSHTIDIEPTSELAKHHPNKKLV 174 Query: 146 KDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNN----CLGTVFHPELL- 200 L I+ L+ KV A + +I AVE +N LG +HPEL+ Sbjct: 175 NSLHHQFIKK------LAPSFKVTARTAD-----GMIEAVEGDNLPSWYLGVQWHPELMF 223 Query: 201 -PHTAFQQYFYEKVKNYK 217 +Q F V K Sbjct: 224 QTDPESEQLFQALVDESK 241 >4GUD-A nrPDB Length = 211 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 63/196 (32%), Gaps = 20/196 (10%) Query: 24 KLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPI 83 ++ + R+ + D L +PG V + L+ + ++KP+ Sbjct: 21 AIERLGYAVTISRDPQVVLAADKLFLPG-----VGTASEAMKNLTERDLIELVKRVEKPL 75 Query: 84 WGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSA 143 G C G LL K E ++ + G +D + + L + ++ Sbjct: 76 LGICLGMQLLGKLSEEKGQKADEIVQ-CLGLVDGEV------RLLQTGDLPLPHMGWNTV 128 Query: 144 FKKDLTAAC--IRAP---YIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPE 198 K+ I Y + V T + YG AA++ N G FHPE Sbjct: 129 QVKEGHPLFNGIEPDAYFYFVHSFAMPVGDY-TIAQCEYGQPFSAAIQAGNYYGVQFHPE 187 Query: 199 LLPH--TAFQQYFYEK 212 Q F E Sbjct: 188 RSSKAGARLIQNFLEL 203 >4WIN-A nrPDB Length = 249 Score = 34.0 bits (76), Expect = 0.050, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 67/204 (32%), Gaps = 35/204 (17%) Query: 32 IIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCI 91 ++++++ D+ G+++ GG + + L + + K PI+G C G Sbjct: 51 GVELKDIKDMN-IKGVILSGGPYS----VTEAGSPHLKKEVFEYFLEKKIPIFGICYGMQ 105 Query: 92 LLSKNVENIKLYSNFGNKFSFGGLDITICRN------FYGSQNDSFICSLNIISDSSAFK 145 ++ + S +G D+ I RN Y +F S + + S +K Sbjct: 106 EIAVQMNGEVKKSKTSE---YGCTDVNILRNDNINNITYCR---NFGDSSSAMDLYSNYK 159 Query: 146 KDLTAACIRAPYIREILSDEVKVLATFSHE--SYGPNIIAAVEQNNCLGTV--------- 194 C+ I SD V + E N NCL Sbjct: 160 LMNETCCL----FENIKSDITTVWMNHNDEVTKIPENFYLVSSSENCLICSIYNKEYNIY 215 Query: 195 ---FHPELLPHTAFQQYFYEKVKN 215 +HPE+ + FY N Sbjct: 216 GVQYHPEVYESLDGELMFYNFAYN 239 >4WIM-A nrPDB Length = 568 Score = 34.0 bits (76), Expect = 0.057, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 67/204 (32%), Gaps = 35/204 (17%) Query: 32 IIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCI 91 ++++++ D+ G+++ GG + + L + + K PI+G C G Sbjct: 52 GVELKDIKDMN-IKGVILSGGPYS----VTEAGSPHLKKEVFEYFLEKKIPIFGICYGMQ 106 Query: 92 LLSKNVENIKLYSNFGNKFSFGGLDITICRN------FYGSQNDSFICSLNIISDSSAFK 145 ++ + S +G D+ I RN Y +F S + + S +K Sbjct: 107 EIAVQMNGEVKKSKTSE---YGCTDVNILRNDNINNITYCR---NFGDSSSAMDLYSNYK 160 Query: 146 KDLTAACIRAPYIREILSDEVKVLATFSHE--SYGPNIIAAVEQNNCLGTV--------- 194 C+ I SD V + E N NCL Sbjct: 161 LMNETCCL----FENIKSDITTVWMNHNDEVTKIPENFYLVSSSENCLICSIYNKEYNIY 216 Query: 195 ---FHPELLPHTAFQQYFYEKVKN 215 +HPE+ + FY N Sbjct: 217 GVQYHPEVYESLDGELMFYNFAYN 240 >1L9X-A nrPDB Length = 315 Score = 33.6 bits (75), Expect = 0.071, Method: Composition-based stats. Identities = 36/167 (21%), Positives = 58/167 (34%), Gaps = 16/167 (9%) Query: 44 CDGLVIPGGESTTVRRCCAYENDTLYNAL--VHFIHVLKKPIWGTCAGCILLSKNVENIK 101 +G++ PGG S +RR + ++ L F P+WGTC G LS + Sbjct: 87 INGILFPGG-SVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGEC 145 Query: 102 LYSNFGNKFSFGGLDITICRNFYGSQNDS-----FICSLNIISDSSAFKKDLT--AACIR 154 L + +D+ + NF G Q S F L + + + ++ Sbjct: 146 LLTATDT------VDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVK 199 Query: 155 APYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPELLP 201 + E L VL T + + G +HPE P Sbjct: 200 NFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAP 246 >1K9V-F nrPDB Length = 201 Score = 33.2 bits (74), Expect = 0.095, Method: Composition-based stats. Identities = 45/222 (20%), Positives = 77/222 (34%), Gaps = 29/222 (13%) Query: 4 ITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDL--GLCDGLVIPG----GESTTV 57 + IG++S+ ++ +K + + + V L D L IPG GE + Sbjct: 1 MRIGIISVGPGNIMNLYRGVKRASENFEDVSIELVESPRNDLYDLLFIPGVGHFGEG--M 58 Query: 58 RRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDI 117 RR + L + + + + + G C G LL + E GL + Sbjct: 59 RRL---RENDLIDFVRKHVEDERY-VVGVCLGMQLLFEESE---------EAPGVKGLSL 105 Query: 118 TICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESY 177 I N ++ ++ + FK + + +E VL T ++ Sbjct: 106 -IEGNVVKLRSRRLP---HMGWNEVIFKDTFPNGYYYFVHTYRAVCEEEHVLGTTEYD-- 159 Query: 178 GPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS 219 G +AV + LG FHPE + EKV S Sbjct: 160 GEIFPSAVRKGRILGFQFHPEKSS--KIGRKLLEKVIECSLS 199 >5TW7-A nrPDB Length = 529 Score = 32.8 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 48/163 (29%), Gaps = 42/163 (25%) Query: 45 DGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYS 104 G+++ GG ++ I L P+ G C G ++ ++ Sbjct: 56 KGIILSGGPNSV---------YESDYQADTGIFDLGIPVLGICYGMQFMAHHLGG---EV 103 Query: 105 NFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREIL-- 162 GN+ FG + DS + + D AP ++ Sbjct: 104 QPGNQREFGYAQV--------KTIDS--------GLTRGIQDD-------APNTLDVWMS 140 Query: 163 -SDEVKVL----ATFSHESYGPNIIAAVEQNNCLGTVFHPELL 200 D+V L A P + + G FHPE+ Sbjct: 141 HGDKVSKLPDGFAVIGDTPSCPIAMMENTEKQFYGIQFHPEVT 183 >4OFW-A nrPDB Length = 387 Score = 32.8 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 5/55 (9%) Query: 40 DLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLS 94 DL DGLVIPGG + A LV KPI C G ++L+ Sbjct: 76 DLSKYDGLVIPGGRAPEYLALTASVV-----ELVKEFSRSGKPIASICHGQLILA 125 >3TQI-A nrPDB Length = 527 Score = 32.4 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 49/170 (28%), Gaps = 26/170 (15%) Query: 46 GLVIPGGESTTVRRCCAYENDTLYNALVH--FIHVLKKPIWGTCAGCILLSKNVENIKLY 103 G+++ GG T TL + L FI + P+ G C G ++ + Sbjct: 56 GIILSGGPETV----------TLSHTLRAPAFIFEIGCPVLGICYGMQTMAYQLGG---K 102 Query: 104 SNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILS 163 N K FG + + + I S + L + I L Sbjct: 103 VNRTAKAEFGHAQLRVLNPAF--------LFDGIEDQVSPQGEPLLDVWMSHGDIVSELP 154 Query: 164 DEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKV 213 + A + A + G FHPE+ + V Sbjct: 155 PGFEATACTDNSPLAA---MADFKRRFFGLQFHPEVTHTPQGHRILAHFV 201 >2VXO-A nrPDB Length = 697 Score = 32.1 bits (71), Expect = 0.19, Method: Composition-based stats. Identities = 33/178 (18%), Positives = 63/178 (35%), Gaps = 44/178 (24%) Query: 25 LQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIW 84 L+ P+ I + ++I GG ++ E+ ++ I + KP+ Sbjct: 61 LETPAFAIKE-------QGFRAIIISGGPNS-----VYAEDAPWFDPA---IFTIGKPVL 105 Query: 85 GTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITI---CRNFYGSQNDSFICSLNIISDS 141 G C G +++K + G +I++ C F G Q + + +++ Sbjct: 106 GICYGMQMMNKVFGGTVHKKSVRED---GVFNISVDNTCSLFRGLQKE----EVVLLTHG 158 Query: 142 SAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPEL 199 + K ++D KV+A + G A E G FHPE+ Sbjct: 159 DSVDK---------------VADGFKVVARSGNIVAG----IANESKKLYGAQFHPEV 197 >2A9V-A nrPDB Length = 212 Score = 32.1 bits (71), Expect = 0.21, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 36/102 (35%), Gaps = 14/102 (13%) Query: 29 SLNIIQVRN---VHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWG 85 ++ V N +L DGLV+ GG E D L ++ +I PI G Sbjct: 37 GVDTKIVPNDIDSSELDGLDGLVLSGGAPN-----IDEELDKL-GSVGKYIDDHNYPILG 90 Query: 86 TCAGCILLSKNVENIKLYSNFGNKFSFGGLDITI--CRNFYG 125 C G ++ + FG +++ N +G Sbjct: 91 ICVGAQFIA---LHFGASVVKAKHPEFGKTKVSVMHSENIFG 129 >5IVA-B nrPDB Length = 192 Score = 31.7 bits (70), Expect = 0.25, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 31/99 (31%), Gaps = 8/99 (8%) Query: 94 SKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACI 153 + N +L +F+ +D++ RN YG +L + Sbjct: 1 APNTSGFQLRGLGDAQFALKEIDVSA-RNAYGPTVRELKETLENSGVKVTSNAPYHLVLV 59 Query: 154 R-------APYIREILSDEVKVLATFSHESYGPNIIAAV 185 R Y E ++ T ++E G N + + Sbjct: 60 REDNQQRTVSYTGSARGAEFELTNTINYEIVGANDLVLM 98 >2VPI-A nrPDB Length = 218 Score = 31.7 bits (70), Expect = 0.26, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 57/161 (35%), Gaps = 37/161 (22%) Query: 42 GLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIK 101 ++I GG ++ E+ ++ I + KP+ G C G +++K Sbjct: 66 QGFRAIIISGGPNS-----VYAEDAPWFDPA---IFTIGKPVLGICYGMQMMNKVFGGTV 117 Query: 102 LYSNFGNKFSFGGLDITI---CRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYI 158 + G +I++ C F G Q + + +++ + K Sbjct: 118 HKKSVRED---GVFNISVDNTCSLFRGLQKE----EVVLLTHGDSVDK------------ 158 Query: 159 REILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPEL 199 ++D KV+A + G A E G FHPE+ Sbjct: 159 ---VADGFKVVARSGNIVAG----IANESKKLYGAQFHPEV 192 >4L6H-A nrPDB Length = 789 Score = 30.9 bits (68), Expect = 0.48, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 17/46 (36%), Gaps = 1/46 (2%) Query: 13 GDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVR 58 GD P++ L + + VR L ++ G++ + Sbjct: 278 GDVRPNLKAIENLPVAGFHFDFVRVPEQLDEV-ASILKDGQTLSAG 322 >4YDS-A nrPDB Length = 228 Score = 30.1 bits (66), Expect = 0.75, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 22/55 (40%), Gaps = 4/55 (7%) Query: 152 CIRAPYIREILSDEVKVLATFSHE----SYGPNIIAAVEQNNCLGTVFHPELLPH 202 IR+ I I+ D + +LA FS E + +I V + HP+ Sbjct: 110 FIRSKNIDFIVIDSLSILAAFSKEKQLLQFMKDIRVLVNTGKMILFTIHPDTFDE 164 >2N8X-A nrPDB Length = 166 Score = 30.1 bits (66), Expect = 0.76, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 29/97 (29%), Gaps = 8/97 (8%) Query: 96 NVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIR- 154 +L +F+ +D++ RN YG +L +R Sbjct: 1 GTSGFQLRGLGDAQFALKEIDVSA-RNAYGPTVRELKETLENSGVKVTSNAPYHLVLVRE 59 Query: 155 ------APYIREILSDEVKVLATFSHESYGPNIIAAV 185 Y E ++ T ++E G N + + Sbjct: 60 DNQQRTVSYTGSARGAEFELTNTINYEIVGANDLVLM 96 >3EBK-A nrPDB Length = 176 Score = 29.7 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 42/129 (32%), Gaps = 2/129 (1%) Query: 91 ILLSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTA 150 I+ + E + Y + ++FS+ ++ + G + + + Sbjct: 30 IIAAGTSEALTQYKCWIDRFSYDDALVSKYTDSQGKNRTTIRGRTKFEGNKFTIDYNDKG 89 Query: 151 ACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFY 210 APY +L+ + + A N Q FHP+L Q Y Sbjct: 90 KAFSAPY--SVLATDYENYAIVEGCPAAANGHVIYVQLRMTLRRFHPKLGDKEMLQHYTL 147 Query: 211 EKVKNYKYS 219 ++V K + Sbjct: 148 DQVNQNKKA 156 >2VKT-A nrPDB Length = 289 Score = 29.4 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 55/188 (29%), Gaps = 36/188 (19%) Query: 39 HDLGLCDGLVIPGGEST--TVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGC----IL 92 L DG+++PGG T+ + A + + K P G C G I Sbjct: 86 QKLCKADGILVPGGFGIRGTLGKLQA----------ISWARTKKIPFLGVCLGMQLAVIE 135 Query: 93 LSKNVENIKLYSNFGNKFSF-----------------GGLDITICRNFYGSQNDSFICSL 135 ++N N+K + + + G + + I R + ++N Sbjct: 136 FARNCLNLKDADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRK-- 193 Query: 136 NIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVF 195 + D ++ P + + + II +G F Sbjct: 194 -LYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQF 252 Query: 196 HPELLPHT 203 HPE Sbjct: 253 HPEFSSRP 260 >2VRN-A nrPDB Length = 190 Score = 29.4 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 31/85 (36%), Gaps = 19/85 (22%) Query: 8 VLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDT 67 + S++GD EP + V + + DGL++PGG + Sbjct: 49 IQSMKGDIEPQEK---------YRVDHVVSEVQVSDYDGLLLPGGT-------VNPDKLR 92 Query: 68 LYNALVHFIHVL---KKPIWGTCAG 89 L + F+ + KPI C G Sbjct: 93 LEEGAMKFVRDMYDAGKPIAAICHG 117 >1WL8-A nrPDB Length = 189 Score = 29.4 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 23/76 (30%), Gaps = 13/76 (17%) Query: 29 SLNIIQVRNVHDLGLCD-----GLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPI 83 + + N L G++ GG S EN ++ PI Sbjct: 24 GVETKIIPNTTPLEEIKAMNPKGIIFSGGPS--------LENTGNCEKVLEHYDEFNVPI 75 Query: 84 WGTCAGCILLSKNVEN 99 G C G L++K Sbjct: 76 LGICLGHQLIAKFFGG 91 >1OI4-A nrPDB Length = 193 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 5/49 (10%) Query: 45 DGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILL 93 D L++PGG S R ++ F+ KP++ C G LL Sbjct: 88 DALLLPGGHSPDYLR----GDNRFVTFTRDFV-NSGKPVFAICHGPQLL 131 >1YKW-A nrPDB Length = 435 Score = 28.6 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 24/67 (35%), Gaps = 9/67 (13%) Query: 17 PHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFI 76 P I F +++ ++ + + L D +++PG T ++ + Sbjct: 289 PFIASFSRMEKYGIHSKVMTKLQRLAGLDAVIMPG---------FGDRVMTPEEEVLENV 339 Query: 77 HVLKKPI 83 KP+ Sbjct: 340 IECTKPM 346 >2VDJ-A nrPDB Length = 301 Score = 28.2 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 37/210 (17%), Positives = 69/210 (32%), Gaps = 27/210 (12%) Query: 6 IGVLSLQGDF-----EPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRC 60 IG LQ D E H++ + + + R++ + DGL+I G T+ Sbjct: 58 IGNTPLQLDVHLLHMESHLSRNVAQEHLTSFYKTFRDIEN-EKFDGLIITGAPVETL--- 113 Query: 61 CAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITIC 120 ++E + L + K + T +I + G +G + Sbjct: 114 -SFEEVDYWEELKRIMEYSKTNVTST-----------LHICWGAQAGLYHHYGVQKYPLK 161 Query: 121 RNFYGSQNDSFICSL--NIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYG 178 +G F + + F + A R +RE EVK L ++ Sbjct: 162 EKMFG----VFEHEVREQHVKLLQGFDELFFAVHSRHTEVRESDIREVKELTLLANSEEA 217 Query: 179 PNIIAAVEQNNCLGTVFHPELLPHTAFQQY 208 + ++ + + H E T Q+Y Sbjct: 218 GVHLVIGQEGRQVFALGHSEYSCDTLKQEY 247 >5X9W-A nrPDB Length = 816 Score = 27.8 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 25/76 (32%), Gaps = 11/76 (14%) Query: 133 CSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLG 192 +++ + S+ + L A + E L V P ++ N + Sbjct: 374 AQIDLSATGSSLLETLKAVFPETLPVAETLKAAV-----------MPEPSVWLKDGNVIN 422 Query: 193 TVFHPELLPHTAFQQY 208 FHPEL Q + Sbjct: 423 HGFHPELDELRRIQNH 438 >2YWB-A nrPDB Length = 503 Score = 27.8 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 12/34 (35%) Query: 75 FIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGN 108 + P+ G C G LL++ + + Sbjct: 66 RLFSSGLPLLGICYGMQLLAQELGGRVERAGRAE 99 >1GVH-A nrPDB Length = 396 Score = 27.4 bits (59), Expect = 4.3, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 19/50 (38%) Query: 168 VLATFSHESYGPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYK 217 ++ +F E +A LG PE PH +QY + + K Sbjct: 166 LITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGK 215 >1G2I-A nrPDB Length = 166 Score = 27.4 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Query: 42 GLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAG-CILLSKNVENI 100 D LV+PGG + R ++ + KP+ C G IL+S V Sbjct: 60 EEFDALVLPGGRAPERVRLNEKAV-----SIARKMFSEGKPVASICHGPQILISAGVLRG 114 Query: 101 KLYSNFG 107 + +++ Sbjct: 115 RKGTSYP 121 >4HI0-E nrPDB Length = 199 Score = 27.0 bits (58), Expect = 6.3, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 30/87 (34%), Gaps = 6/87 (6%) Query: 117 ITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPY--IREILSDEVKVLATFSH 174 I + Y ++ F+C +++ + P+ IRE S ++ + Sbjct: 32 AVITNDIYTKEDAEFMCKNSVMPRERIIGVETGG----CPHTAIREDASMNLEAVEEMHG 87 Query: 175 ESYGPNIIAAVEQNNCLGTVFHPELLP 201 ++ + L F+PEL Sbjct: 88 RFPNLELLLIESGGDNLSATFNPELAD 114 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.126 0.316 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,458,766 Number of Sequences: 36641 Number of extensions: 258680 Number of successful extensions: 781 Number of sequences better than 10.0: 40 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 685 Number of HSP's gapped (non-prelim): 60 length of query: 219 length of database: 10,336,785 effective HSP length: 93 effective length of query: 126 effective length of database: 6,929,172 effective search space: 873075672 effective search space used: 873075672 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 57 (26.7 bits)