BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q8BHN3 (944 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5IEF-A nrPDB 1890 0.0 5HJR-A nrPDB 1748 0.0 5DKX-A nrPDB 721 0.0 5DJW-A nrPDB 355 4e-98 5KZW-A nrPDB 333 2e-91 3WEN-A nrPDB 303 2e-82 3L4Y-A nrPDB 288 1e-77 3LPO-A nrPDB 271 1e-72 2G3M-A nrPDB 268 6e-72 3POC-A nrPDB 265 5e-71 6JR6-A nrPDB 244 1e-64 3TOP-A nrPDB 236 3e-62 5I24-A nrPDB 205 6e-53 5JOV-A nrPDB 181 2e-45 1XSK-A nrPDB 154 1e-37 6DRU-A nrPDB 141 1e-33 5F7C-A nrPDB 141 2e-33 4XPS-A nrPDB 120 4e-27 5I0E-B nrPDB 118 2e-26 5X3I-A nrPDB 113 3e-25 5AEG-A nrPDB 104 2e-22 5OHS-A nrPDB 92 7e-19 1RLU-A nrPDB 32 1.1 5WYJ-U4 nrPDB 32 1.3 3MBT-A nrPDB 31 2.0 4CXU-A nrPDB 31 3.1 >5IEF-A nrPDB Length = 913 Score = 1890 bits (4896), Expect = 0.0, Method: Compositional matrix adjust. Identities = 912/912 (100%), Positives = 912/912 (100%) Query: 33 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 92 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ Sbjct: 1 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 60 Query: 93 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 152 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT Sbjct: 61 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 120 Query: 153 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE 212 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE Sbjct: 121 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE 180 Query: 213 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 272 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE Sbjct: 181 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 240 Query: 273 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK 332 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK Sbjct: 241 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK 300 Query: 333 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 392 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF Sbjct: 301 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 360 Query: 393 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 452 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM Sbjct: 361 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 420 Query: 453 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 512 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF Sbjct: 421 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 480 Query: 513 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 572 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH Sbjct: 481 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 540 Query: 573 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 632 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM Sbjct: 541 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 600 Query: 633 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ Sbjct: 601 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 660 Query: 693 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL Sbjct: 661 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 720 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 812 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR Sbjct: 721 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 780 Query: 813 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 872 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL Sbjct: 781 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 840 Query: 873 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 932 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG Sbjct: 841 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 900 Query: 933 VSVASDWSIHLR 944 VSVASDWSIHLR Sbjct: 901 VSVASDWSIHLR 912 >5HJR-A nrPDB Length = 857 Score = 1748 bits (4527), Expect = 0.0, Method: Compositional matrix adjust. Identities = 857/912 (93%), Positives = 857/912 (93%), Gaps = 55/912 (6%) Query: 33 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 92 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ Sbjct: 1 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 60 Query: 93 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 152 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT Sbjct: 61 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 120 Query: 153 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE 212 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPR Sbjct: 121 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPR--------------------------- 153 Query: 213 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 272 EPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE Sbjct: 154 ---------EPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 204 Query: 273 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK 332 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNT Sbjct: 205 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNT--- 261 Query: 333 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 392 PQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF Sbjct: 262 ----------------PQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 305 Query: 393 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 452 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM Sbjct: 306 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 365 Query: 453 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 512 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF Sbjct: 366 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 425 Query: 513 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 572 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH Sbjct: 426 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 485 Query: 573 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 632 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM Sbjct: 486 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 545 Query: 633 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ Sbjct: 546 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 605 Query: 693 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL Sbjct: 606 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 665 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 812 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR Sbjct: 666 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 725 Query: 813 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 872 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL Sbjct: 726 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 785 Query: 873 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 932 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG Sbjct: 786 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 845 Query: 933 VSVASDWSIHLR 944 VSVASDWSIHLR Sbjct: 846 VSVASDWSIHLR 857 >5DKX-A nrPDB Length = 951 Score = 721 bits (1861), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/920 (43%), Positives = 540/920 (58%), Gaps = 74/920 (8%) Query: 33 VDRSNFKTCDESSFCKRQRSIRPGL-------SPYRALLDTLQLGPDALTVHLIHEVT-- 83 V ++K CD+S FC+R R+ SPY+ +T ++ + Sbjct: 5 VKEHDWKKCDQSGFCRRNRAYADHALSAISWESPYKIAPETGSFKDGQYQAIILKTINDH 64 Query: 84 --KVLLVLELQGLQKNMTRIRIDE-------------LEPRRPRYRVPD--VLVADPPTA 126 V L L + L+ R+ IDE + R+ RY + V+V Sbjct: 65 GETVRLPLTVSFLESGTARVTIDEEKRQKGEIELRHDSKARKERYNEAEQWVIVGGMTLD 124 Query: 127 RLSVSGRDDNSVELTVAEGP---YKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRA 183 + + +D + ++TV GP ++ + PF +D D + + N +GL+ EH R Sbjct: 125 KGAKVDYEDKT-QMTVKYGPSSKFEATIKFAPFSIDFKRDGASHIKFNDQGLLNIEHWR- 182 Query: 184 PRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTS 243 P++ DP +PE G+ +P++ +E +D+ WEE+F ++DSKP GP S Sbjct: 183 PKI-----DPP----PEPEKKEGE-QQPDKKEEAPREDDSTWWEESFGGNTDSKPRGPES 232 Query: 244 VGLDFSLPGMEHVYGIPEHADSLRLKVTEGGE-----PYRLYNLDVFQYELNNPMALYGS 298 VGLD S G EHV+GIP HA L LK T GGE PYR+YN DVF+Y L++PM LYGS Sbjct: 233 VGLDISFVGYEHVFGIPSHASPLSLKQTRGGEGNYNEPYRMYNADVFEYILDSPMTLYGS 292 Query: 299 VPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSE 358 +P + AH +GIFWLNAAETWVDI+ K G T W SE Sbjct: 293 IPFMQAHRKDSSVGIFWLNAAETWVDITKGKDSKNPLA------LGVKSKITTRTHWFSE 346 Query: 359 SGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDD 418 SG++DVF+ LGP+ D+ +YA LTGT A+P FSLGYHQ RWNY + DV +VD+ D Sbjct: 347 SGLLDVFVFLGPTPKDIISKYAELTGTTAMPQEFSLGYHQCRWNYVSDEDVKDVDRKMDK 406 Query: 419 HNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYR 478 NMP DVIWLDIE+ D K+YFTWD F P+ M + L + RKLV I+DPHIK + Y Sbjct: 407 FNMPYDVIWLDIEYTDEKKYFTWDKHSFKDPIGMGKQLEAHGRKLVTIIDPHIKNTNNYP 466 Query: 479 VHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLY 538 V +EL++ L VKT+DGS +EGWCWPGS+ + D NP R WW +F +D ++G+ N + Sbjct: 467 VVDELKSKDLAVKTKDGSIFEGWCWPGSSHWIDAFNPAAREWWKGLFKYDKFKGTMENTF 526 Query: 539 VWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRS-GGIERP 597 +WNDMNEPSVFNGPEVTM KD +H+G WEHRD+HN+ G+ AT L+ R G RP Sbjct: 527 IWNDMNEPSVFNGPEVTMPKDNLHHGNWEHRDVHNLNGMTFQNATYHALLSRKPGEHRRP 586 Query: 598 FVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEP 657 FVL+RAFF+GSQR GA+WTGDNTA+W +LK SIPM LS + G F GADVGGFF NP+ Sbjct: 587 FVLTRAFFAGSQRLGAMWTGDNTADWGYLKASIPMVLSQGIAGFPFAGADVGGFFGNPDK 646 Query: 658 ELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQ 717 +LL RWYQ G + PFFRAHAH+D RREP+L Y I AL RYSLLP WYT F Sbjct: 647 DLLTRWYQTGIFYPFFRAHAHIDARRREPYLTGEPYNTIIAAALRLRYSLLPSWYTAFRH 706 Query: 718 AHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGD-ALLIHPVSDAGAHGVQVYLPGQEEVW 776 AH +G P+++P++ +P + + I+DQF +G+ LL PV+D V +++P EV+ Sbjct: 707 AHLDGTPIIKPMFYTHPSEEAGLPIDDQFFIGNTGLLAKPVTDKDRTSVDIWIP-DSEVY 765 Query: 777 YDIQSYQ--KHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVAL 834 YD +Y +T L L IP+ RGG + R RRSS MK DP TL V L Sbjct: 766 YDYFTYDIISAAKSKTATLDAPLEKIPLLMRGGHVFARRDIPRRSSALMKWDPYTLVVVL 825 Query: 835 SPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPI----W-- 888 A+G+L++DDG +F+Y+ + +++ RRF F +TL +SAD +G + I W Sbjct: 826 GNDRKAEGDLYVDDGDSFDYE-KGQYIHRRFIFDANTL--TSADYEGRDDASIKEGEWLK 882 Query: 889 ------IERVVIMGAGKPAA 902 +E+++++GA PAA Sbjct: 883 KMRTVNVEKIIVVGA--PAA 900 >5DJW-A nrPDB Length = 697 Score = 355 bits (912), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 214/621 (34%), Positives = 328/621 (52%), Gaps = 51/621 (8%) Query: 248 FSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSF 307 ++P +YG E SL G+ +L+N D Y ++ LY S P ++ Sbjct: 56 LTVPEGTSIYGGGEVTGSL----LRNGKTIKLWNTDSGAYGVDKGTRLYQSHPWMMG--V 109 Query: 308 HRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLM 367 +D F + TW S+T K I SE VF++ Sbjct: 110 RKDGTAFGILFDTTWKAELSSTDEK--------------------IELKSEGIPFRVFII 149 Query: 368 LGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIW 427 S V R + LTGT + P ++LGY Q R++Y ++ V+E+ F +PCDVIW Sbjct: 150 DRESPQAVIRGLSELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFRLKRIPCDVIW 209 Query: 428 LDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHG 487 +DI++ DG R FT++P FP P + L + ++DP KVD Y V++ + Sbjct: 210 MDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIRGFHSAWMIDPGAKVDPNYFVYKSGTEND 269 Query: 488 LYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPS 547 ++VKT DG ++ G WPG+A++PDFT+P++ WW N++ +G VWND+NEP Sbjct: 270 VWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQGVDG---VWNDVNEPQ 326 Query: 548 VFNGPEVTMLKDAVHYGGWE-----HRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSR 602 + + P TM +D +H GG + H HN+YG + A+ +G++ + +RPF+L+R Sbjct: 327 INDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGFLMVKASREGILD-ARPEKRPFILTR 385 Query: 603 AFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVR 662 + F G QR+ A WTGDN + WDHLK+S+PM L+L L G F GAD+GGF N + +L Sbjct: 386 SNFLGGQRYAATWTGDNGSCWDHLKMSVPMSLTLGLSGQPFSGADIGGFLFNADADLFGN 445 Query: 663 WYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEG 722 W GA+ PF R HA T +EPW+ + +DA R AL +RY LLP++YTL ++A G Sbjct: 446 WIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASRIALERRYILLPYFYTLLHEASTNG 505 Query: 723 FPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSY 782 P+MRP++ P+D+S + E+ F++GD LLI P A Q LP + +W ++ Sbjct: 506 MPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIP-----AFANQPALP--KGIWKELSLV 558 Query: 783 QKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQG 842 + G Q + RGG I+P ++ +++ DP+TL V L QG A G Sbjct: 559 E---GDQNDKYQAKMKI-----RGGAIIPTGKIIQNTTENSL-DPLTLLVCLDEQGKASG 609 Query: 843 ELFLDDGHTFNYQTRHEFLLR 863 ++ D G ++Y+ LL+ Sbjct: 610 NMYWDAGDGWSYKKGDYSLLQ 630 >5KZW-A nrPDB Length = 874 Score = 333 bits (854), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 241/734 (32%), Positives = 349/734 (47%), Gaps = 99/734 (13%) Query: 246 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLA- 304 L SLP +++ G+ EH L L + L+N D+ N LYGS P LA Sbjct: 170 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 223 Query: 305 ---HSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGI 361 S H G+F LN SN L P + W S GI Sbjct: 224 EDGGSAH---GVFLLN---------SNAMDVVL-------------QPSPALSWRSTGGI 258 Query: 362 IDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNM 421 +DV++ LGP V +QY + G +PP + LG+H RW Y A +V + + Sbjct: 259 LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHF 318 Query: 422 PCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDS---GYR 478 P DV W D+++ D +R FT++ F M++ L R+ + IVDP I YR Sbjct: 319 PLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYR 378 Query: 479 VHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLY 538 ++E G+++ G G WPGS ++PDFTNP AWW +M + + P Sbjct: 379 PYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDG 436 Query: 539 VWNDMNEPSVF--------------NGPEV----------TMLKDAVHYGGWEHRDIHNI 574 +W DMNEPS F N P V + + H H ++HN+ Sbjct: 437 MWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNL 496 Query: 575 YGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCL 634 YGL +A+ L++ G RPFV+SR+ F+G R+ WTGD + W+ L S+P L Sbjct: 497 YGLTEAIASHRALVKARG--TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEIL 554 Query: 635 SLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQ 694 L+G+ GADV GF N EL VRW Q+GA+ PF R H L + +EP+ + Q Sbjct: 555 QFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQ 614 Query: 695 DAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLI 754 A+R AL RY+LLP YTLF+QAH G V RPL++++P+D ST++++ Q + G+ALLI Sbjct: 615 QAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLI 674 Query: 755 HPVSDAGAHGVQVYLPGQEEVWYDIQSY------------------QKHHGPQTLYLPVT 796 PV AG V Y P WYD+Q+ H Q + LP Sbjct: 675 TPVLQAGKAEVTGYFP--LGTWYDLQTVPIEALGSLPPPPAAPREPAIHSEGQWVTLPAP 732 Query: 797 LSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQT 856 L +I V R G I+P +++ + P+ L VAL+ G A+GELF DDG + Sbjct: 733 LDTINVHLRAGYIIPLQGPGLTTTES-RQQPMALAVALTKGGEARGELFWDDGESLEVLE 791 Query: 857 RHEF----LLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPE 912 R + L R + + LV +++ G + +++V ++G VL + G P Sbjct: 792 RGAYTQVIFLARNNTIVNELVRVTSEGAG-----LQLQKVTVLGVATAPQQVL-SNGVPV 845 Query: 913 SRLSFQHDPETSVL 926 S +F + P+T VL Sbjct: 846 S--NFTYSPDTKVL 857 >3WEN-A nrPDB Length = 913 Score = 303 bits (777), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 218/701 (31%), Positives = 334/701 (47%), Gaps = 96/701 (13%) Query: 246 LDFSLPGME-HVYGIPEHAD-SLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLL 303 L SLP + H+YG+ EH + +L + L+N D+ + N + LYGS Sbjct: 196 LSSSLPAQQAHLYGLGEHTKPTFQLA---HNQILTLWNADIASF--NRDLNLYGS----- 245 Query: 304 AHSFHRDL----------GIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDI 353 H F+ D+ G+F LN+ V+ + + + G Sbjct: 246 -HPFYMDVRSSPMVGSTHGVFLLNSNGMDVEYTGDRITYKVIG----------------- 287 Query: 354 RWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVD 413 GIID+++ G + V QY L G A P ++ G+HQ RW YRD ++ V Sbjct: 288 ------GIIDLYIFAGRTPEMVLDQYTKLIGRPAPMPYWAFGFHQCRWGYRDVNEIETVV 341 Query: 414 QGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKR----RKLVAIVDP 469 + + +P +V+W DI++ D + FT DP FP L+ ++ +K ++ V I+DP Sbjct: 342 DKYAEARIPLEVMWTDIDYMDAFKDFTLDPVHFP--LDKMQQFVTKLHRNGQRYVPILDP 399 Query: 470 HIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDN 529 I + Y +++K RDG+ Y G WPG YPDF +P R++W + Sbjct: 400 GINTNKSYGTFIRGMQSNVFIK-RDGNPYLGSVWPGPVYYPDFLDPAARSFWVD--EIKR 456 Query: 530 YEGSAPNLYVWNDMNEPSVF--------------------NGPEV-----TMLKDAVHYG 564 + P +W DMNE S F +G V T+ A+HYG Sbjct: 457 FRDILPIDGIWIDMNEASNFITSAPTPGSTLDNPPYKINNSGGRVPINSKTIPATAMHYG 516 Query: 565 GWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWD 624 + HN+YG AT + L++ S ERPF+LSR+ F+GS ++ A WTGDN A WD Sbjct: 517 NVTEYNAHNLYGFLESQATREALVRTSN--ERPFLLSRSTFAGSGKYTAHWTGDNAARWD 574 Query: 625 HLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRR 684 L+ SIP L+ L G+ GAD+ GF ++ EL RW Q+GA+ PF R H+ DT + Sbjct: 575 DLQYSIPTMLNFGLFGMPMIGADICGFAESTTEELCRRWIQLGAFYPFSRDHSARDTTHQ 634 Query: 685 EPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIED 744 E +L S A R L RY LLP++YTL Y A+ G P+ RPL+ +P+D++T+ I Sbjct: 635 ELYLWESVAASA-RTVLGLRYQLLPYYYTLMYDANLRGIPIARPLFFTFPDDVATYGISS 693 Query: 745 QFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIP--- 801 QF++G +++ PV GA V Y P W+ + +Y V+LS+ P Sbjct: 694 QFLIGRGIMVSPVLQPGAVSVNAYFPRGN--WFSLFNYTSSVSVSAGTY-VSLSAPPDHI 750 Query: 802 -VFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQ--TRH 858 V G IV ++ + P L V +S + GELFLD+G + Sbjct: 751 NVHIHEGNIVAMQGEA-MTTQAARSTPFHLLVVMSDHVASTGELFLDNGIEMDIGGPGGK 809 Query: 859 EFLLRRFSFSG--STLVSSSADPKGHLETPIWI-ERVVIMG 896 L+R F+ SG + +SS +G+ + W+ +++ I+G Sbjct: 810 WTLVRFFAESGINNLTISSEVVNRGYAMSQRWVMDKITILG 850 >3L4Y-A nrPDB Length = 875 Score = 288 bits (736), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 198/614 (32%), Positives = 302/614 (49%), Gaps = 41/614 (6%) Query: 349 PQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408 P I + + GI+D ++ LG + V ++Y L G ALP ++LG+H SR+ Y + Sbjct: 247 PAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDN 306 Query: 409 VLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVD 468 + EV + +P DV DI++ D +R FT+D F + L + +KLV IVD Sbjct: 307 MREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVD 366 Query: 469 PHIKVDSG----YRVHEELRNHGLYVKTRDG-SDYEGWCWPGSASYPDFTNPRMRAWWSN 523 P I +S Y ++ + ++V + DG + G WPG +PD+TNP WW+ Sbjct: 367 PAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTK 426 Query: 524 MFSFDNYEGSAPNLYVWNDMNEPSVF-------------NGPEVT------------MLK 558 F + +W DMNE S F N P T + Sbjct: 427 EFEL--FHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCM 484 Query: 559 DAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGD 618 DAV + G ++ DIHN+YG + +ATA+ + +R F+L+R+ F+GS +F A W GD Sbjct: 485 DAVQHWGKQY-DIHNLYGYSMAVATAEA-AKTVFPNKRSFILTRSTFAGSGKFAAHWLGD 542 Query: 619 NTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAH 678 NTA WD L+ SIP L L G+ G D+ GF + EL RW Q+GA+ PF R H Sbjct: 543 NTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNG 602 Query: 679 LDTGRREPWLLA--SQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPED 736 ++P S ++ R L RY+LLP+ YTLF++AH G V RPL ++ ED Sbjct: 603 QGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYED 662 Query: 737 MSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQS-YQKHHGPQTLYLPV 795 ST+ + QF+ G LLI PV D GA V Y+P + VWYD ++ Q Q + + + Sbjct: 663 NSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVP--DAVWYDYETGSQVRWRKQKVEMEL 720 Query: 796 TLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQ 855 I + RGG I P + ++ + +P+ L +AL A+GELF DDG T + Sbjct: 721 PGDKIGLHLRGGYIFPT-QQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTV 779 Query: 856 TRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSP-ESR 914 +LL FS + + L + + + + I+G +P+ V ++ G P ++ Sbjct: 780 ANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTS 839 Query: 915 LSFQHDPETSVLIL 928 + +D V I+ Sbjct: 840 PTVTYDSNLKVAII 853 >3LPO-A nrPDB Length = 898 Score = 271 bits (693), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 211/727 (29%), Positives = 337/727 (46%), Gaps = 70/727 (9%) Query: 254 EHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGI 313 +++YGI E R + + + ++ D + NN + + + + + + + G+ Sbjct: 203 DYIYGIGEQVHK-RFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGV 261 Query: 314 FWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVF 373 F +N+ M ++Q P + + GI+D +++LG + Sbjct: 262 FLMNS-----------------NAMEIFIQ-----PTPIVTYRVTGGILDFYILLGDTPE 299 Query: 374 DVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHA 433 V +QY L G A+P ++LG+ SRWNY+ V EV + + +P D DI++ Sbjct: 300 QVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYM 359 Query: 434 DGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVD-----SGYRVHEELRNHGL 488 + K+ FT+D F ++ L +K V I+DP I + + Y +E + Sbjct: 360 EDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNTQHV 419 Query: 489 YVKTRDGSD-YEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPS 547 ++ DGS G WPG YPDFTNP WW+N S + E L W DMNE S Sbjct: 420 WINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGL--WIDMNEVS 477 Query: 548 VF-----NGPEV--------------------TMLKDAVHYGGWEHRDIHNIYGLYVHMA 582 F G V T+ DAV G ++ D+H++YG + +A Sbjct: 478 SFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQY-DVHSLYGYSMAIA 536 Query: 583 TADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLS 642 T +Q+ +R F+L+R+ F+GS R A W GDNTA W+ ++ SI L +L G+ Sbjct: 537 TEQA-VQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIP 595 Query: 643 FCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLA--SQYQDAIRDA 700 GAD+ GF EL RW Q+GA+ PF R H ++P S + R Sbjct: 596 LVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQY 655 Query: 701 LFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDA 760 L RY+LLPF YTLFY+AH G V RP+ ++ ED +++ + +F+ G ALLI PV Sbjct: 656 LTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQ 715 Query: 761 GAHGVQVYLPGQEEVWYDIQSYQKHHGPQT---LYLPVTLSSIPVFQRGGTIVPRWMRVR 817 GA V Y+P + +WYD +S K + +YLP I + RGG I+P Sbjct: 716 GADTVSAYIP--DAIWYDYESGAKRPWRKQRVDMYLPA--DKIGLHLRGGYIIPI-QEPD 770 Query: 818 RSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSA 877 ++ + +P+ L VAL TA+G+ F DDG T + ++L FS S +TL Sbjct: 771 VTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCT 830 Query: 878 DPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSP--ESRLSFQHDPETSVLILRKPGVSV 935 T + + V I+G V + + + +F +D VL++ +++ Sbjct: 831 HSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKLNL 890 Query: 936 ASDWSIH 942 ++S+ Sbjct: 891 GRNFSVQ 897 >2G3M-A nrPDB Length = 693 Score = 268 bits (686), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 178/599 (29%), Positives = 291/599 (48%), Gaps = 68/599 (11%) Query: 242 TSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYE-LNNPMALYGSVP 300 V ++ SL EH+ G+ E A L K + Y +YN+D Y+ +P LY S+P Sbjct: 50 NKVIVEKSLDLKEHIIGLGEKAFELDRK----RKRYVMYNVDAGAYKKYQDP--LYVSIP 103 Query: 301 VLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESG 360 + ++ G F+ +A++ D+ K + P+ + + Sbjct: 104 LFISVKDGVATGYFFNSASKVIFDVGLEEYDKVIVT-----------IPEDSVEF----- 147 Query: 361 IIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN 420 +++ GP + DV +Y LTG LPP+++ GY SR++Y + V+E+ Sbjct: 148 ----YVIEGPRIEDVLEKYTELTGKPFLPPMWAFGYMISRYSYYPQDKVVELVDIMQKEG 203 Query: 421 MPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVH 480 ++LDI + D + FTW P RFP+P +++ L + KL+ IVD I+VD Y Sbjct: 204 FRVAGVFLDIHYMDSYKLFTWHPYRFPEPKKLIDELHKRNVKLITIVDHGIRVDQNYSPF 263 Query: 481 EELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVW 540 L G + + G + G WPG+ YPDF R WW+ + S +G +W Sbjct: 264 --LSGMGKFCEIESGELFVGKMWPGTTVYPDFFREDTREWWAGLISEWLSQGVDG---IW 318 Query: 541 NDMNEPSVFN-GPEV------------------TMLKDAVHY---GGWEHRDIHNIYGLY 578 DMNEP+ F+ E+ T + VHY +H + N Y LY Sbjct: 319 LDMNEPTDFSRAIEIRDVLSSLPVQFRDDRLVTTFPDNVVHYLRGKRVKHEKVRNAYPLY 378 Query: 579 VHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLAL 638 MAT G R+ F+LSRA ++G QR+ +WTGDNT WD LK+ + + L L++ Sbjct: 379 EAMATFKGF--RTSHRNEIFILSRAGYAGIQRYAFIWTGDNTPSWDDLKLQLQLVLGLSI 436 Query: 639 VGLSFCGADVGGFFKNPEPE------LLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 G+ F G D+GGF E LLV++Y + + PF+R+H D EP L Sbjct: 437 SGVPFVGCDIGGFQGRNFAEIDNSMDLLVKYYALALFFPFYRSHKATDGIDTEPVFLPDY 496 Query: 693 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 Y++ +++ + RY LP+ Y+L +A ++G PV+RPL+ ++ +D + IED++M+G L Sbjct: 497 YKEKVKEIVELRYKFLPYIYSLALEASEKGHPVIRPLFYEFQDDDDMYRIEDEYMVGKYL 556 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVP 811 L P+ + V LP + WY+ + + +G + + +P++ R G+I+P Sbjct: 557 LYAPIV-SKEESRLVTLPRGK--WYNYWNGEIINGKSVV---KSTHELPIYLREGSIIP 609 >3POC-A nrPDB Length = 666 Score = 265 bits (678), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 161/581 (27%), Positives = 277/581 (47%), Gaps = 64/581 (11%) Query: 329 TAGKTLFGKMLDYLQG----SGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTG 384 +GKT FG DY G T ++ E+ +D++++ G + +D+ +Q+ + G Sbjct: 96 VSGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIG 155 Query: 385 TQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPT 444 +PP F+ G+ QSRW Y + D V +G+ ++++P D+I++DI++ + FT + Sbjct: 156 RSYIPPKFAFGFGQSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEK 215 Query: 445 RFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWP 504 FP ++ + + +L+ I+D +KV+ GY V+EE + + K DGSD+ WP Sbjct: 216 NFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWP 275 Query: 505 GSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYG 564 G +PD NP R W+ + + F +G WN MNEP++F E L +A + Sbjct: 276 GDTHFPDMLNPEARKWFGDKYRFLIDQGIEG---FWNAMNEPAIFYSSE--GLAEAKEFA 330 Query: 565 G------------W----------------------------EHRDIHNIYGLYVHMATA 584 G W H +HN++G + A Sbjct: 331 GEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAG 390 Query: 585 DGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFC 644 + +R +R + SR+ + G R+G +W GDN + W H+ +++ M SL + G + Sbjct: 391 EAF-ERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYT 449 Query: 645 GADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQR 704 GAD+GGF + +LL+R+ +G + P R HA G RE + + R + R Sbjct: 450 GADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAA--EGTREQECYQFENIEDFRSVINAR 507 Query: 705 YSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHG 764 Y L+P+ Y+ + +A +PL YP+D +EDQ MLG+ ++I PV + A G Sbjct: 508 YRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARG 567 Query: 765 VQVYLPGQEEVWY-----DIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRS 819 VYLP EE+ + D ++ Y+ V L+ +P+F R G +P V + Sbjct: 568 RYVYLP--EEMKFIKFMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIP----VAEA 621 Query: 820 SDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEF 860 ++C+KD + +G++ L+ DDG +Y + + Sbjct: 622 AECVKDIDTENMQLIGYEGSSY-TLYEDDGIHKDYDKKENY 661 >6JR6-A nrPDB Length = 838 Score = 244 bits (624), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 180/619 (29%), Positives = 284/619 (45%), Gaps = 58/619 (9%) Query: 254 EHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGI 313 E +G+ E + +L + G Y+++N D Y +N LY S+P ++ + GI Sbjct: 156 EQFFGLGEKSGNLNRR----GSAYKMWNSDQPCYGVNED-PLYKSIPFFMSSYRY---GI 207 Query: 314 FWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVF 373 F+ N +T S + DY S E P +G + + M G Sbjct: 208 FFDNTYKTEFKFGSESN---------DYY--SFEAP---------AGQMVYYFMFGNDYK 247 Query: 374 DVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHA 433 ++ + Y +LTG +PP ++LG+ Q R +Y E E+ F +PCD+I+ DI Sbjct: 248 EIIQNYIALTGKPIMPPKWALGFSQCRGDYTREDQAREIAAEFRKRKIPCDIIYQDIGWT 307 Query: 434 DGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTR 493 +G + F W + P M++ L+ K++ DP I + + E L R Sbjct: 308 EGLQDFDWRKNNYNNPKGMVKDLSDMGFKMIVSQDPVISQANQQQWKEADALGHLVKDVR 367 Query: 494 DGSDYEG-WCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYV---WNDMNEPSVF 549 G Y+ W W G+ DFT P + WW + Y+ N V W DM EP+ Sbjct: 368 TGKSYDMPWPWGGNCGVVDFTKPEVADWWGS------YQQKPLNDGVRGFWTDMGEPAWS 421 Query: 550 NGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQ 609 N V L H G H +IHN+YG + + + +R F ++RA ++G Q Sbjct: 422 NEDAVDRLNMKHHLG--MHNEIHNVYGFTWDKVVTEQFYKHNPN-KRIFQMTRAAYAGLQ 478 Query: 610 RFGAVWTGDNTAE------WDHLKISIPMCLSLALVGLSFCGADVGGFFKNPE-----PE 658 R+ W+GD+ W + IP+ LS + + F D+ G+ + + E Sbjct: 479 RYTFGWSGDSGNGSNVLDGWKQMANQIPVGLSAGMGLIPFWTCDISGYCGDIKDYDAMAE 538 Query: 659 LLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQA 718 L VRW Q G + P RAH H EPW ++ ++ R ++ +Y L P+ YT +A Sbjct: 539 LYVRWLQFGVFTPLSRAH-HEGGNAVEPWKFGTEAENISRKSIELKYKLFPYLYTYAREA 597 Query: 719 HKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYD 778 H G P+MR L ++YP D TF + QF++G LL+ PV + GA VYLP E W D Sbjct: 598 HDTGLPIMRALLLEYPNDKETFKLNGQFLVGKELLVAPVVEQGAVTKDVYLPEGE--WID 655 Query: 779 IQSYQ-KHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQ 837 + + K+ G Q + + L++IPVF + G+I+P+ M V + D K P+T + Sbjct: 656 FNNCKTKYKGEQWITVDAPLNTIPVFVKKGSIIPQ-MPVMQYIDEKKVYPVTFDIFPGNL 714 Query: 838 GTAQGELFL-DDGHTFNYQ 855 F DDG + +Y+ Sbjct: 715 NKETSFTFYEDDGESRDYE 733 >3TOP-A nrPDB Length = 908 Score = 236 bits (602), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 184/642 (28%), Positives = 297/642 (46%), Gaps = 70/642 (10%) Query: 349 PQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408 P + + + G++D ++ LGP+ V +QY L G + P +SLG+ R+ Y+++++ Sbjct: 248 PLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSE 307 Query: 409 VLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVD 468 + + +P DV + DI++ + + FT P +F ++ + + +++ I+D Sbjct: 308 IASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILD 366 Query: 469 PHIKVDSG--YRVHEELRNHGLYVKT-RDGSDYEGWCWP--------GS----------- 506 P I + Y +++K DG G WP GS Sbjct: 367 PAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYR 426 Query: 507 --ASYPDFTNPRMRAWWSNMFS--FDNYEGSAPNLY---VWNDMNEPSVF-NGPEVTMLK 558 ++PDF WW ++N + +L +W DMNEPS F NG + Sbjct: 427 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 486 Query: 559 DA-VHYGGW------------------------------EHRDIHNIYGLYVHMATADGL 587 DA +++ + +H ++HN+YG T + + Sbjct: 487 DASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAV 546 Query: 588 IQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGAD 647 + +G +R V++R+ F S R+ W GDNTA WD LK SI + +L G+S+ GAD Sbjct: 547 QEVTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 604 Query: 648 VGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSL 707 + GFF++ E E+ VRW Q+GA+ PF R H + T R++P + + R L RY+L Sbjct: 605 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 664 Query: 708 LPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQV 767 LP+ YTL ++AH EG V+RPL ++ D T+ I+ QF+LG A L+ PV + A V Sbjct: 665 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 724 Query: 768 YLPGQEEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDD 826 Y P WYD + + + LP L I + RGG I+P W ++ + Sbjct: 725 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRQK 781 Query: 827 PITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLET- 885 + +AL +GTA G LF DDG + + + + L FS S +T+ S T Sbjct: 782 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTN 841 Query: 886 PIWIERVVIMGAGK-PAAVVLQTKGSPESRLSFQHDPETSVL 926 P+ + + I G G P V + SF +DP T VL Sbjct: 842 PLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVL 883 >5I24-A nrPDB Length = 836 Score = 205 bits (522), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 158/529 (29%), Positives = 246/529 (46%), Gaps = 32/529 (6%) Query: 346 GETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRD 405 G+T ++ ++SG L+ G S + + +TG Q LPP ++LG SR+ YR Sbjct: 193 GKTESDILQLEAKSGRSAYILVAGNSYPSLIENFTQVTGRQPLPPRWALGSFASRFGYRS 252 Query: 406 EADVLEVDQGFDDHNMPCDVIWLDIE--HADGKRY---FTWDPTRFPQPLNMLEHLASKR 460 EA+ Q + + P D I LD+ D K + WD FP PL+M+ + Sbjct: 253 EAETRATVQKYKTEDFPLDTIVLDLYWFGKDIKGHMGNLDWDKENFPTPLDMMADFKQQG 312 Query: 461 RKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAW 520 K V I +P + + S R + ++ L K G + G+ D + W Sbjct: 313 VKTVLITEPFV-LTSSKRWDDAVKAKAL-AKDPQGQPKAFELYFGNGGIIDVFSKEGSRW 370 Query: 521 WSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYG-LYV 579 +S+++ + +G A W D+ EP + PE D H G + +HN YG + Sbjct: 371 FSSIYKDLSKQGVAG---WWGDLGEPEMH--PE-----DTQHAIG-DADTVHNAYGHRWA 419 Query: 580 HMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAV-WTGDNTAEWDHLKISIPMCLSLAL 638 M L Q RPF++ RA F GSQR+G + WTGD + W L + + L ++L Sbjct: 420 EMLYQQQLDQFPE--LRPFIMMRAGFVGSQRYGMIPWTGDVSRTWGGLASQVELALQMSL 477 Query: 639 VGLSFCGADVGGFF--KNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDA 696 +G + +D+GGF + + E+ +RW Q G +QP +R H D EP + + Sbjct: 478 LGFGYIHSDLGGFADGETLDKEMYIRWLQYGVFQPVYRPHGQ-DHIPSEPVFQDEETKAI 536 Query: 697 IRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHP 756 +R + RY +LP+ YT YQ G P+MRPL+ ++ + + + GD+LL+ P Sbjct: 537 LRPLVKLRYRMLPYIYTAAYQNTLTGMPLMRPLFFSDEKNPALIDNKTSYFWGDSLLVTP 596 Query: 757 VSDAGAHGVQVYLPGQEEVWYDI---QSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRW 813 ++ AG V + P + VW+D YQ P L LP L +IPV + G +P Sbjct: 597 ITQAGVESVSI--PAPKGVWFDFWKDTRYQTDGAP--LTLPTDLHTIPVLVKAGAFMPYV 652 Query: 814 MRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLL 862 V + D D + A + AQGE+F DDG N R++F L Sbjct: 653 PAVSTTEDYRSDSLEIHYYADASVPLAQGEIFEDDGKDPNSIKRNQFDL 701 >5JOV-A nrPDB Length = 955 Score = 181 bits (458), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 153/560 (27%), Positives = 250/560 (44%), Gaps = 63/560 (11%) Query: 355 WMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQ 414 W + +D + M G ++ DV Y SLTG + P +++G+ QSR Y + ++L + Sbjct: 368 WSEMTKQLDYYFMAGENMDDVISGYRSLTGKSPVMPKWAMGFWQSREKYNTQEEMLGALK 427 Query: 415 GFDDHNMPCDVIWLDIEH----ADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPH 470 GF D +P D I LD H A G F D RFP P M++ + + +++ V P Sbjct: 428 GFRDRKIPLDNIVLDWNHWPENAWGSHEF--DKARFPDPKAMVDSIHAMHARMMISVWPK 485 Query: 471 IKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPG-SASYPDFTNPRMRA-WWSNMF--- 525 V + + +E +G + + W PG + D +P R +W M+ Sbjct: 486 FYVTTEH--FKEFDENGWMYQQSVKDSLKDWVGPGYHYGFYDAYDPDARKLFWKQMYEHY 543 Query: 526 ---SFDNY--EGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVH 580 D + + S PN+ D+ GP T L + + N Y L Sbjct: 544 YPLGIDAWWMDASEPNVRDCTDLEYRKALCGP--TALGSSTEF--------FNAYALMNA 593 Query: 581 MATADGLIQRS-GGIERPFVLSRAFFSGSQRFG-AVWTGDNTAEWDHLKISIPMCLSLAL 638 A DG QR +R F+L+R+ F+G QR+ A W+GD W+ +K I L+ A+ Sbjct: 594 EAIYDG--QRGVDNNKRVFLLTRSGFAGLQRYSTATWSGDIGTRWEDMKAQISAGLNFAM 651 Query: 639 VGLSFCGADVGGFF-----------------KNPE----PELLVRWYQMGAYQPFFRAHA 677 G+ + D+GGF +N + EL RWYQ GA+ P +RAH Sbjct: 652 SGIPYWTMDIGGFCVENRYVAGQKQWNATKTENADYKEWRELNTRWYQFGAFVPLYRAHG 711 Query: 678 HLDTGRREPWLLASQYQDAIRDALFQ---RYSLLPFWYTLFYQAHKEGFPVMRPLWVQYP 734 RE W +A + A + ++ RY+++P+ Y+L + + +MRPL + + Sbjct: 712 QYPF--REIWEIAPEGHPAYQSVVYYTKLRYNMMPYIYSLAGMTWFDDYTIMRPLVMDFT 769 Query: 735 EDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLP 794 D I DQFM G + ++ PV G ++Y P Q E WYD S + G + + Sbjct: 770 ADAEVNDIGDQFMFGPSFMVSPVYRYGDRSREIYFP-QAEGWYDFYSGKFQAGGERKVIE 828 Query: 795 VTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNY 854 IP++ R G I+P ++ +D + I L++ G + L+ D+G +NY Sbjct: 829 APYERIPLYVRAGAIIPFGDDIQY-TDEKPAEHIRLYIYQGADG--EFTLYEDEGVNYNY 885 Query: 855 -QTRHEFLLRRFSFSGSTLV 873 Q + + ++ + TLV Sbjct: 886 EQGMYAMIPMKYDEATKTLV 905 >1XSK-A nrPDB Length = 778 Score = 154 bits (390), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 146/560 (26%), Positives = 239/560 (42%), Gaps = 56/560 (10%) Query: 346 GETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGY--HQSRWNY 403 G + +++ ES ++ F++ GP+ V +Y TG ALPP +S G S Sbjct: 221 GSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTSFTTN 280 Query: 404 RDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRY--FTWDPTRFPQPLNMLEHLASKRR 461 DEA V G + N+P V D ++ F WDP FP P M+ L +K Sbjct: 281 YDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRRLKAKGL 340 Query: 462 KLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCW-PGSASYPDFTNPRMRAW 520 K+ ++P+I S V +EL+ G +K DGS ++ W PG A Y DFTNP W Sbjct: 341 KICVWINPYIGQKS--PVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIY-DFTNPDACKW 397 Query: 521 WSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVH 580 ++ D +G M + D + G + + +HN Y Y++ Sbjct: 398 YA-----DKLKGLVA-------MGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYA-YIY 444 Query: 581 MATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVG 640 +++ + G E + +R+ G+Q+F W GD A ++ + S+ LS+ L G Sbjct: 445 NELVWNVLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSG 504 Query: 641 LSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDA 700 F D+GGF + RW G R H R PW + D +R Sbjct: 505 FGFWSHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHG--SKSYRVPWAYDDESCDVVRFF 562 Query: 701 LFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPV-SD 759 + ++P+ Y +A+ G P+MR + +++P+D + ++ Q+MLGD +++ PV ++ Sbjct: 563 TQLKCRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTE 622 Query: 760 AGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRS 819 AG VQ YLP E W + + G + S+PV+ R T++ +R Sbjct: 623 AG--DVQFYLP--EGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRP 678 Query: 820 SDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADP 879 + +GTA H FN Q HE + + GS + + A Sbjct: 679 D------------YVWHEGTA--------FHLFNLQDGHEAVCEVPAADGSVIFTLKAAR 718 Query: 880 KGHLETPIWIERVVIMGAGK 899 G+ + + GAG+ Sbjct: 719 TGNT--------ITVTGAGE 730 >6DRU-A nrPDB Length = 718 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 136/495 (27%), Positives = 205/495 (41%), Gaps = 58/495 (11%) Query: 364 VFLMLGPSVFDVFRQ-YASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMP 422 V + P +D +Q ++LTG PP FSLGY QS+ Y ++ +V + Q F D N+P Sbjct: 219 VIVAAQPGDYDTLQQRISALTGRAPAPPDFSLGYIQSKLRYENQTEVELLAQNFHDRNIP 278 Query: 423 CDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLAS-KRRKLVAIVDPHIKVDSGYRVHE 481 +I +D + + + DP +P M + + +++A + P + DS + Sbjct: 279 VSMIVIDYQSWAHQGDWALDPRLWPNVAQMSARVKNLTGAEMMASLWPSVADDS--VNYA 336 Query: 482 ELRNHGLYVKTRDGSDYEGWCWPGS--ASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYV 539 L+ +GL TRDG W GS +Y D TNP R + +M + Y+ N Sbjct: 337 ALQANGLLSATRDGPGTTD-SWNGSYIRNY-DSTNPSARKFLWSMLKKNYYDKGIKNF-- 392 Query: 540 WNDMNEPSVF-----NGPEVTMLKDA------VHYGGWEHRDIHNIYGLYVHMATADGLI 588 W D + N + T ++ V+Y + +Y A +G Sbjct: 393 WIDQADGGALGEAYENNGQSTYIESIPFTLPNVNYAAGTQLSVGKLYPWAHQQAIEEGFR 452 Query: 589 Q----RSGGIERPFVLSRAFFSGSQRFGA-VWTGDNTAEWDHLKISIPMCLSLALVGLSF 643 + G LSR+ + GSQRF + +W+GD T+ WD L + + LS A G + Sbjct: 453 NATDTKEGSACDHVSLSRSGYIGSQRFCSMIWSGDTTSVWDTLAVQVASGLSAAATGWGW 512 Query: 644 CGADVGGF-----------FKNPE-PELLVRWYQMGAYQPFFRAHAHLD-------TGRR 684 D GGF PE EL VRW + PF R H T Sbjct: 513 WTVDAGGFEVDSTVWWSGNIDTPEYRELYVRWLAWTTFLPFMRTHGSRTCYFQDAYTCAN 572 Query: 685 EPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFS--- 741 EPW + I + RY L + ++F Q H G +MRPL++ + + S Sbjct: 573 EPWSYGASNTPIIVSYIHLRYQLGAYLKSIFNQFHLTGRSIMRPLYMDFEKTDPKISQLV 632 Query: 742 ------IEDQFMLGDALLIHPVSDAGAHGVQVYLP--GQEEV--WYDIQSYQKHHGPQTL 791 Q+M G LL+ PV+ VYLP GQ W + + + G Q + Sbjct: 633 SSNSNYTTQQYMFGPRLLVSPVTLPNVTEWPVYLPQTGQNNTKPWTYWWTNETYAGGQVV 692 Query: 792 YLPVTLSSIPVFQRG 806 +P L IPVF G Sbjct: 693 KVPAPLQHIPVFHLG 707 >5F7C-A nrPDB Length = 761 Score = 141 bits (355), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 128/486 (26%), Positives = 224/486 (46%), Gaps = 43/486 (8%) Query: 353 IRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEV 412 ++++S+ ++D F++ G ++ ++ R Y LTG ++PPL+S G SR Y +V E+ Sbjct: 271 VQFLSDQAMLDAFVIAGDTMEEILRGYRDLTGYPSMPPLWSFGVWMSRMTYFSADEVNEI 330 Query: 413 DQGFDDHNMPCDVIWLDIE--HADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPH 470 + PCDVI LD D + ++ RFP P ++ L ++ P+ Sbjct: 331 CDRMRAEHYPCDVIHLDTGWFRTDWLCEWKFNEERFPDPKGFIQRLKKNGYRVSLWQLPY 390 Query: 471 IKVDSGYRVHEELRNHGLYVKTR----DGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFS 526 + D+ ++ E N + T+ DGS++ + G+ DFT P+ W Sbjct: 391 VAEDAE-QIEEAKANEYIAPLTKQQDTDGSNFSALDYAGTI---DFTYPKATEW------ 440 Query: 527 FDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADG 586 Y+G L DM + + DAV Y G + ++N+Y L A + Sbjct: 441 ---YKGLLKQLL---DMGVTCIKTDFGENIHMDAV-YKGMKPELLNNLYALLYQKAAYEI 493 Query: 587 LIQRSG-GIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCG 645 + +G GI V +RA ++G QR+ W GD+ + WD + S+ L L G +F Sbjct: 494 TKEVTGDGI----VWARAAWAGCQRYPLHWGGDSCSSWDGMAGSLKGGLHFGLSGFAFWS 549 Query: 646 ADVGGFFKNPE-------PELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIR 698 DV GF P ++ +RW Q G + R H T +REPW + ++ Sbjct: 550 HDVPGFHTLPNFMNSIVAEDVYMRWTQFGVFTSHIRYHG---TNKREPWHYPA-IAPLVK 605 Query: 699 DALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVS 758 RYSL+P+ A + G+P+++ L + +PED + I+D++ G+ L+ PV Sbjct: 606 KWWKLRYSLIPYIIEQSKLAVESGWPLLQALILHHPEDKLCWHIDDEYYFGNDFLVAPVM 665 Query: 759 DAGAHGVQVYLP-GQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVR 817 ++ + +YLP GQ ++ + Q + +Y+P L +PV+ R ++P + Sbjct: 666 NS-ENRRDIYLPEGQWVNFFTGERLQGGRWLKEVYVP--LEEMPVYVRENAVIPIYPEEV 722 Query: 818 RSSDCM 823 +D M Sbjct: 723 NCTDEM 728 >4XPS-A nrPDB Length = 720 Score = 120 bits (300), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 140/553 (25%), Positives = 220/553 (39%), Gaps = 72/553 (13%) Query: 362 IDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNM 421 ++V++ GP D ++Y L G LPP + LG+ Q + DV + F + Sbjct: 200 VEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDFKEKGY 259 Query: 422 PCDVIWLDIEHADGKRY---FTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYR 478 P D + L+ K Y F+WD +R+P P + ++ + + +L ++P+I D+ + Sbjct: 260 PLDFVGLE-PGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPF- 317 Query: 479 VHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLY 538 ++E +K GS W G PDFT R + N D E Sbjct: 318 -YKE-------IKPYTGSHT---VWLGLV--PDFTMAEARKPFFNQLLKDQIERGVSGYK 364 Query: 539 VWNDMNEPSVFNGPEVTMLKDAVHY-GGWEHRDIHNIYGLYVHMATADGLIQRSGGIERP 597 + + +G + + DA + G + YGL V +A+ QR+ ER Sbjct: 365 I-------AEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQRN---ERT 414 Query: 598 FVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEP 657 F L RA G F V D D + I + L + G Sbjct: 415 FGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSG-------- 466 Query: 658 ELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQ 717 E +R +Q + P +A + PW D + AL R ++P+WY+ F + Sbjct: 467 EEWLRRFQSNVFSPMAMINAWASGTK--PWSYPEVEADVKKFALL-RMQMMPYWYSAFAR 523 Query: 718 AHKEGFPVMRPLWVQ---------------------YPEDMSTFSIEDQFMLGDALLIHP 756 H EG P R + ++ Y E S I+DQ+M GD LL+ P Sbjct: 524 YHFEGMPPFRGMGLEEGFRQDAKVEKLNKVNLEENPYAEAASK-EIKDQYMAGDDLLVAP 582 Query: 757 VSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRV 816 + AG +V LP + WYD + + + L + L IPV+ R G IVP + Sbjct: 583 MF-AGEKSRKVVLPKGK--WYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMMPAL 639 Query: 817 RRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSF----SGSTL 872 S + + L + + +L+ DDG TFNY+ + +F R SG Sbjct: 640 LNSPKS--NQKVDLEIRYYGNKPGEFKLYDDDGETFNYE-KGDFSWRTIRVEKDKSGKVK 696 Query: 873 VSSSADPKGHLET 885 S SA KG + T Sbjct: 697 GSISAAVKGKVNT 709 >5I0E-B nrPDB Length = 733 Score = 118 bits (295), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 148/612 (24%), Positives = 235/612 (38%), Gaps = 78/612 (12%) Query: 240 GPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPM-ALYGS 298 G V + G EHV G E D L + RL ++ QY+ Y Sbjct: 159 GTHRVKFALRIEGDEHVVGFGERYDQLDQR------GLRLDSVVFEQYKAQGKHHRTYLP 212 Query: 299 VP-VLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMS 357 +P + + R G TW D+++ + + L + D+ + + Sbjct: 213 MPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILI--------------EVDLGFEA 258 Query: 358 ESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFD 417 E + S DV + + G A P + G S + ++ V+E Sbjct: 259 EKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHR 318 Query: 418 DHNMPCDVI----WLDIEHADGKRYFTWDPTR----------------FPQPLNMLEHLA 457 + +P V+ W D E R + P + +P P M+ L Sbjct: 319 NEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELH 378 Query: 458 SKRRKLVAIVDPHIKVD-----SGYRVHEELRNHGLYVKTRDGSDYE--GWCWPGSASYP 510 + +++ P K D L G VK DG+ Y+ GW +P +A P Sbjct: 379 ERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFP-NALMP 437 Query: 511 DFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMN-EPSVFNGPEVTMLKDAVHYGGWEHR 569 D + R WW+ Y+ D++ + +G E D + G Sbjct: 438 DLSTEAGRQWWTEQ-----------RRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGD 486 Query: 570 DIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKIS 629 + +N+Y V+ A A G + RS G + P SR+ F+GSQ G W GD + W+ + S Sbjct: 487 EGNNLYP--VNYARAYGDLLRSAG-KYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSS 543 Query: 630 IPMCLSLALVGLSFCGADVGGFFKN-PEPELLVRWYQMGAYQPFFRAHAH-----LDTGR 683 I ++ G+ + G D+ GF PE EL R + + P + H+ L Sbjct: 544 ITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRD 603 Query: 684 REPWLLASQYQ-----DAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMS 738 R PW +A Q D R R +L P+ Q + G P+MR ++ + +D Sbjct: 604 RTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPE 663 Query: 739 TFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLS 798 ++ Q+MLGD LLI+PV+ GA YLP E W D S + G + V Sbjct: 664 IWAHPRQYMLGDELLINPVTAPGATTWTTYLP--EGQWEDYWSGEVSEGGHLVTRAVGWD 721 Query: 799 SIPVFQRGGTIV 810 IPV++R G + Sbjct: 722 IIPVYRRVGAAL 733 >5X3I-A nrPDB Length = 743 Score = 113 bits (283), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 118/414 (28%), Positives = 183/414 (44%), Gaps = 58/414 (14%) Query: 425 VIWLDIEHA---DGKRY----FTWDPT-RFPQPLNMLEHLASKRRKLVAIVDPHIKVD-S 475 IW D +A DG + F++ P +P P M++ L ++ K++ P K + S Sbjct: 343 TIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFS 402 Query: 476 GYRVHEE---LRNHGLYVKTRDGSDYE--GWCWPGSASYPDFTNPRMRAWWSNM------ 524 +V + + G V DG+ Y GW +P A PD + R R WW+ Sbjct: 403 TGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFP-QALMPDLSVQRTRDWWTEKRRYLVE 461 Query: 525 -FSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMAT 583 F D ++ +A + W D V+ G + + +N+Y VH A Sbjct: 462 HFDVDGFK-TAGGEHAWG----------------HDLVYADGRKGDEGNNLYP--VHYAR 502 Query: 584 ADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSF 643 A G + RS G + P SRA F+GSQ G W GD + W + S+ L+ A G+ + Sbjct: 503 AFGDLLRSAG-KAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVY 561 Query: 644 CGADVGGFFKN-PEPELLVRWYQMGAYQPFFRAHAHLDTGR-----REPWLLASQYQDAI 697 G D+ GF P+ EL +R A+ P + H+ + + R PW +A D Sbjct: 562 WGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDR 621 Query: 698 RDALFQRY-----SLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 LF+R+ SL+P+ + P+MRPL+ + D ++ Q++LGD L Sbjct: 622 VVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDEL 681 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYL-PVTLSSIPVFQR 805 LI+PV + GA YLP E W D+ + + P L V L +PV+ R Sbjct: 682 LINPVLEPGATTWTTYLPAGE--WIDVWTGDRV--PSGLVTRDVPLEVVPVYCR 731 >5AEG-A nrPDB Length = 686 Score = 104 bits (259), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 102/391 (26%), Positives = 160/391 (40%), Gaps = 44/391 (11%) Query: 435 GKRY---FTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVK 491 GKR + W+ +PQ + ++ + + +A ++P++ D + EE HG K Sbjct: 299 GKRVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYINPYVASDK--DLCEEAAQHGYLAK 356 Query: 492 TRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNG 551 G DY D TNP AW+ + + E D E Sbjct: 357 DASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMA--DFGE------ 408 Query: 552 PEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRF 611 + D + G +HN + + L + +G + RA +GSQ++ Sbjct: 409 ---YLPTDTYLHNGVSAEIMHNAWPALWAKCNYEAL-EETGKLGEILFFMRAGSTGSQKY 464 Query: 612 GAV-WTGDNTAEW---DHLKISIPMCLSLALVGLSFCGADVGG----FFKNPEPELLVRW 663 + W GD +W D L +P LSLA+ G +D+GG F ELL+RW Sbjct: 465 STMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRW 524 Query: 664 YQMGAYQPFFRAHAHLDTGRR--EPWLLASQYQDAIRDALFQRYS-----LLPFWYTLFY 716 A+ P R H G R + W DA A F R + L P+ Sbjct: 525 CDFSAFTPMMRTHE----GNRPGDNWQFDG---DAETIAHFARMTTVFTTLKPYLKEAVA 577 Query: 717 QAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVW 776 K G PVMRPL++ Y +D T++++ Q++LG +L+ PV + G +YLP E+ W Sbjct: 578 LNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLP--EDNW 635 Query: 777 YDIQSYQKHHGPQ-TLYLPVTLSSIPVFQRG 806 + + G + T+ P+ PVF R Sbjct: 636 VHAWTGEAFRGGEVTVNAPI--GKPPVFYRA 664 >5OHS-A nrPDB Length = 672 Score = 92.4 bits (228), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 108/395 (27%), Positives = 165/395 (41%), Gaps = 51/395 (12%) Query: 435 GKRYFTWD----PTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYV 490 G R F WD TR+P + LA + + + V+P++ VD + + G + Sbjct: 281 GARLF-WDWQANDTRYPHLRQKIAELADQGIRFLGYVNPYLCVDG--PLFPVAESAGYFA 337 Query: 491 KTRDGSDYEGWCWPGSASYPDFTNPRMRAWW------SNMFSFDNYEGSAPNLYVW-NDM 543 DG DFTNP W+ NM F L W D Sbjct: 338 TDVDGKTALVDFGEFDCGVVDFTNPAAADWFAAAIIGKNMLDF--------GLSGWMADF 389 Query: 544 NEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRA 603 E + D G + + +HN + A G+ R E F + RA Sbjct: 390 GE---------YLPIDIKLSNGVDAKLMHNAWPTLWAEVNAKGVESRGKTGEALFFM-RA 439 Query: 604 FFSGSQRFG-AVWTGDNTAEW---DHLKISIPMCLSLALVGLSFCGADVGGF---FKNPE 656 F+G Q +W G+ + ++ D L I LS L+G ++ +D+GG+ F N Sbjct: 440 GFTGVQAHCPLIWGGNQSVDFSRHDGLVTVICGALSSGLMGNAYHHSDIGGYTSLFGNVR 499 Query: 657 -PELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYS-----LLPF 710 EL++RW +M A+ P R H G R P QD A F R + L P+ Sbjct: 500 TAELIMRWTEMAAFTPVMRTH----EGNR-PRDNLQIDQDETVLAHFARMTAIYVALAPY 554 Query: 711 WYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLP 770 +L +A K G PV RPL++ Y + T++++D ++ G +L+ PV AG +YLP Sbjct: 555 LKSLSAEAAKTGLPVQRPLFLHYENEPQTYAVQDCYLYGADMLVAPVWKAGETQRSLYLP 614 Query: 771 GQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQR 805 G E W + S ++H G + + + L VF R Sbjct: 615 GHGE-WVHLWSGKRHAGGRDITVETPLGEPAVFYR 648 >1RLU-A nrPDB Length = 382 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 36/63 (57%), Gaps = 3/63 (4%) Query: 281 NLDVFQYELNNPM---ALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGK 337 +L + +N+P+ ++ G+ VL++ + DLG+F +N A + V +++ +FG Sbjct: 237 SLKAAEIAINSPLLEASMEGAQGVLMSIAGGSDLGLFEINEAASLVQDAAHPDANIIFGT 296 Query: 338 MLD 340 ++D Sbjct: 297 VID 299 >5WYJ-U4 nrPDB Length = 189 Score = 32.0 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 6/97 (6%) Query: 37 NFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQK 96 N + F + ++I+P PY+ L+DT + ++ ++ + ++ L Sbjct: 43 NIPQVSSALFFQYNQAIKP---PYQVLIDTNFIN---FSIQKKVDIVRGMMDCLLAKCNP 96 Query: 97 NMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGR 133 +T + ELE P+YR+ L DP RLS S + Sbjct: 97 LITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHK 133 >3MBT-A nrPDB Length = 168 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 23/128 (17%) Query: 401 WNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTR----------FPQPL 450 ++ RD+ + +++G++ P +W + ++GK YFT PTR F Sbjct: 46 YSLRDDGGLNVINKGYN----PDRGMW---QQSEGKAYFTGAPTRAALKVSFFGPFYGGY 98 Query: 451 NMLEHLASKRRKLVAIVDPHI--KVDSGYRVHEELRNHGLYVKTRDGSDYEGWCW---PG 505 N++ R LV+ D + + +E++ L V TR+G D + W PG Sbjct: 99 NVIALDREYRHALVSGPDRDYLWILSRTPTISDEVKQEMLAVATREGFDVSKFIWVQQPG 158 Query: 506 SA-SYPDF 512 SA S+P F Sbjct: 159 SAWSHPQF 166 >4CXU-A nrPDB Length = 536 Score = 30.8 bits (68), Expect = 3.1, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 335 FGKMLDYLQGSGETPQTDIRWMSESG----IIDVFLMLGPSVFDVFRQY 379 G+++DYL+ GE T + +MS++G +++ F GP + D ++ Sbjct: 294 IGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFLDRH 342 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5IEF-A nrPDB 1360 0.0 5HJR-A nrPDB 1268 0.0 5DKX-A nrPDB 1021 0.0 3L4Y-A nrPDB 726 0.0 3LPO-A nrPDB 713 0.0 5KZW-A nrPDB 703 0.0 3TOP-A nrPDB 652 0.0 3WEN-A nrPDB 651 0.0 5DJW-A nrPDB 643 0.0 6JR6-A nrPDB 618 e-177 2G3M-A nrPDB 579 e-165 3POC-A nrPDB 556 e-158 1XSK-A nrPDB 543 e-154 5I24-A nrPDB 515 e-146 5I0E-B nrPDB 500 e-141 5JOV-A nrPDB 500 e-141 5F7C-A nrPDB 485 e-137 4XPS-A nrPDB 455 e-128 5X3I-A nrPDB 408 e-114 6DRU-A nrPDB 406 e-113 5AEG-A nrPDB 386 e-107 5OHS-A nrPDB 344 1e-94 Sequences not found previously or not previously below threshold: 3MI6-A nrPDB 54 3e-07 5M0X-A nrPDB 53 7e-07 2YFN-A nrPDB 43 5e-04 2VKT-A nrPDB 37 0.052 5OT1-A nrPDB 36 0.064 3HQ1-A nrPDB 34 0.43 3HPX-A nrPDB 33 0.51 5NIL-A nrPDB 33 0.53 2PFD-A nrPDB 33 0.62 1QD1-A nrPDB 31 1.9 1A8Q-A nrPDB 31 2.2 3UXF-A nrPDB 31 2.8 3ISR-A nrPDB 31 3.4 3AWQ-A nrPDB 31 3.5 >5IEF-A nrPDB Length = 913 Score = 1360 bits (3519), Expect = 0.0, Method: Composition-based stats. Identities = 912/912 (100%), Positives = 912/912 (100%) Query: 33 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 92 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ Sbjct: 1 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 60 Query: 93 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 152 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT Sbjct: 61 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 120 Query: 153 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE 212 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE Sbjct: 121 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE 180 Query: 213 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 272 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE Sbjct: 181 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 240 Query: 273 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK 332 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK Sbjct: 241 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK 300 Query: 333 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 392 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF Sbjct: 301 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 360 Query: 393 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 452 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM Sbjct: 361 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 420 Query: 453 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 512 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF Sbjct: 421 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 480 Query: 513 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 572 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH Sbjct: 481 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 540 Query: 573 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 632 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM Sbjct: 541 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 600 Query: 633 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ Sbjct: 601 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 660 Query: 693 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL Sbjct: 661 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 720 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 812 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR Sbjct: 721 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 780 Query: 813 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 872 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL Sbjct: 781 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 840 Query: 873 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 932 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG Sbjct: 841 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 900 Query: 933 VSVASDWSIHLR 944 VSVASDWSIHLR Sbjct: 901 VSVASDWSIHLR 912 >5HJR-A nrPDB Length = 857 Score = 1268 bits (3282), Expect = 0.0, Method: Composition-based stats. Identities = 857/912 (93%), Positives = 857/912 (93%), Gaps = 55/912 (6%) Query: 33 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 92 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ Sbjct: 1 VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQ 60 Query: 93 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 152 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT Sbjct: 61 GLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILT 120 Query: 153 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPE 212 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPR Sbjct: 121 AQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPR--------------------------- 153 Query: 213 ETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 272 EPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE Sbjct: 154 ---------EPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE 204 Query: 273 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGK 332 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSN Sbjct: 205 GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSN---- 260 Query: 333 TLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 392 TPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF Sbjct: 261 ---------------TPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLF 305 Query: 393 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 452 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM Sbjct: 306 SLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNM 365 Query: 453 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 512 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF Sbjct: 366 LEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF 425 Query: 513 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 572 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH Sbjct: 426 TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIH 485 Query: 573 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 632 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM Sbjct: 486 NIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPM 545 Query: 633 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ Sbjct: 546 CLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 605 Query: 693 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL Sbjct: 606 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 665 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 812 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR Sbjct: 666 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 725 Query: 813 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 872 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL Sbjct: 726 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 785 Query: 873 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 932 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG Sbjct: 786 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPG 845 Query: 933 VSVASDWSIHLR 944 VSVASDWSIHLR Sbjct: 846 VSVASDWSIHLR 857 >5DKX-A nrPDB Length = 951 Score = 1021 bits (2640), Expect = 0.0, Method: Composition-based stats. Identities = 393/915 (42%), Positives = 536/915 (58%), Gaps = 72/915 (7%) Query: 33 VDRSNFKTCDESSFCKRQRSIRPGL-------SPYRALLDTLQLGPDALTVHLIHEVT-- 83 V ++K CD+S FC+R R+ SPY+ +T ++ + Sbjct: 5 VKEHDWKKCDQSGFCRRNRAYADHALSAISWESPYKIAPETGSFKDGQYQAIILKTINDH 64 Query: 84 --KVLLVLELQGLQKNMTRIRIDE-------------LEPRRPRYRVPD--VLVADPPTA 126 V L L + L+ R+ IDE + R+ RY + V+V Sbjct: 65 GETVRLPLTVSFLESGTARVTIDEEKRQKGEIELRHDSKARKERYNEAEQWVIVGGMTLD 124 Query: 127 RLSVSGRDDNSVELTVAEGP---YKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRA 183 + + +D + ++TV GP ++ + PF +D D + + N +GL+ EH R Sbjct: 125 KGAKVDYEDKT-QMTVKYGPSSKFEATIKFAPFSIDFKRDGASHIKFNDQGLLNIEHWR- 182 Query: 184 PRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTS 243 P++ DP +PE G+ +P++ +E +D+ WEE+F ++DSKP GP S Sbjct: 183 PKI-----DPP----PEPEKKEGE-QQPDKKEEAPREDDSTWWEESFGGNTDSKPRGPES 232 Query: 244 VGLDFSLPGMEHVYGIPEHADSLRLKVTEGGE-----PYRLYNLDVFQYELNNPMALYGS 298 VGLD S G EHV+GIP HA L LK T GGE PYR+YN DVF+Y L++PM LYGS Sbjct: 233 VGLDISFVGYEHVFGIPSHASPLSLKQTRGGEGNYNEPYRMYNADVFEYILDSPMTLYGS 292 Query: 299 VPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSE 358 +P + AH +GIFWLNAAETWVDI+ K G T W SE Sbjct: 293 IPFMQAHRKDSSVGIFWLNAAETWVDITKGKDSKNPLAL------GVKSKITTRTHWFSE 346 Query: 359 SGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDD 418 SG++DVF+ LGP+ D+ +YA LTGT A+P FSLGYHQ RWNY + DV +VD+ D Sbjct: 347 SGLLDVFVFLGPTPKDIISKYAELTGTTAMPQEFSLGYHQCRWNYVSDEDVKDVDRKMDK 406 Query: 419 HNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYR 478 NMP DVIWLDIE+ D K+YFTWD F P+ M + L + RKLV I+DPHIK + Y Sbjct: 407 FNMPYDVIWLDIEYTDEKKYFTWDKHSFKDPIGMGKQLEAHGRKLVTIIDPHIKNTNNYP 466 Query: 479 VHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLY 538 V +EL++ L VKT+DGS +EGWCWPGS+ + D NP R WW +F +D ++G+ N + Sbjct: 467 VVDELKSKDLAVKTKDGSIFEGWCWPGSSHWIDAFNPAAREWWKGLFKYDKFKGTMENTF 526 Query: 539 VWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQR-SGGIERP 597 +WNDMNEPSVFNGPEVTM KD +H+G WEHRD+HN+ G+ AT L+ R G RP Sbjct: 527 IWNDMNEPSVFNGPEVTMPKDNLHHGNWEHRDVHNLNGMTFQNATYHALLSRKPGEHRRP 586 Query: 598 FVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEP 657 FVL+RAFF+GSQR GA+WTGDNTA+W +LK SIPM LS + G F GADVGGFF NP+ Sbjct: 587 FVLTRAFFAGSQRLGAMWTGDNTADWGYLKASIPMVLSQGIAGFPFAGADVGGFFGNPDK 646 Query: 658 ELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQ 717 +LL RWYQ G + PFFRAHAH+D RREP+L Y I AL RYSLLP WYT F Sbjct: 647 DLLTRWYQTGIFYPFFRAHAHIDARRREPYLTGEPYNTIIAAALRLRYSLLPSWYTAFRH 706 Query: 718 AHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGD-ALLIHPVSDAGAHGVQVYLPGQEEVW 776 AH +G P+++P++ +P + + I+DQF +G+ LL PV+D V +++P EV+ Sbjct: 707 AHLDGTPIIKPMFYTHPSEEAGLPIDDQFFIGNTGLLAKPVTDKDRTSVDIWIP-DSEVY 765 Query: 777 YDIQSYQK--HHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVAL 834 YD +Y +T L L IP+ RGG + R RRSS MK DP TL V L Sbjct: 766 YDYFTYDIISAAKSKTATLDAPLEKIPLLMRGGHVFARRDIPRRSSALMKWDPYTLVVVL 825 Query: 835 SPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIW------ 888 A+G+L++DDG +F+Y+ + +++ RRF F +TL +SAD +G + I Sbjct: 826 GNDRKAEGDLYVDDGDSFDYE-KGQYIHRRFIFDANTL--TSADYEGRDDASIKEGEWLK 882 Query: 889 ------IERVVIMGA 897 +E+++++GA Sbjct: 883 KMRTVNVEKIIVVGA 897 >3L4Y-A nrPDB Length = 875 Score = 726 bits (1874), Expect = 0.0, Method: Composition-based stats. Identities = 212/731 (29%), Positives = 335/731 (45%), Gaps = 65/731 (8%) Query: 246 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAH 305 L LP +VYG+ EH + + + + ++N D + + + L Sbjct: 168 LSTRLPS-TNVYGLGEHVHQ-QYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLED 225 Query: 306 SFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVF 365 + G+F +N+ V + P I + + GI+D + Sbjct: 226 ASGLSFGVFLMNSNAMEVVL----------------------QPAPAITYRTIGGILDFY 263 Query: 366 LMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDV 425 + LG + V ++Y L G ALP ++LG+H SR+ Y ++ EV + +P DV Sbjct: 264 VFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDV 323 Query: 426 IWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSG----YRVHE 481 DI++ D +R FT+D F + L + +KLV IVDP I +S Y ++ Sbjct: 324 QHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYD 383 Query: 482 ELRNHGLYVKTRDG-SDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVW 540 + ++V + DG + G WPG +PD+TNP WW+ F + +W Sbjct: 384 RGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTKEFE--LFHNQVEFDGIW 441 Query: 541 NDMNEPSVFNGPEV-------------------------TMLKDAVHYGGWEHRDIHNIY 575 DMNE S F V T+ DAV + G + DIHN+Y Sbjct: 442 IDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWG-KQYDIHNLY 500 Query: 576 GLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLS 635 G + +ATA+ + +R F+L+R+ F+GS +F A W GDNTA WD L+ SIP L Sbjct: 501 GYSMAVATAEA-AKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLE 559 Query: 636 LALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLA--SQY 693 L G+ G D+ GF + EL RW Q+GA+ PF R H ++P S Sbjct: 560 FNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLL 619 Query: 694 QDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALL 753 ++ R L RY+LLP+ YTLF++AH G V RPL ++ ED ST+ + QF+ G LL Sbjct: 620 LNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLL 679 Query: 754 IHPVSDAGAHGVQVYLPGQEEVWYDIQSY-QKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 812 I PV D GA V Y+P + VWYD ++ Q Q + + + I + RGG I P Sbjct: 680 ITPVLDEGAEKVMAYVP--DAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPT 737 Query: 813 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTL 872 ++ + +P+ L +AL A+GELF DDG T + +LL FS + + L Sbjct: 738 QQ-PNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRL 796 Query: 873 VSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSP-ESRLSFQHDPETSVLILRKP 931 + + + + I+G +P+ V ++ G P ++ + +D V I+ Sbjct: 797 EVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDI 856 Query: 932 GVSVASDWSIH 942 + + +++ Sbjct: 857 DLLLGEAYTVE 867 >3LPO-A nrPDB Length = 898 Score = 713 bits (1839), Expect = 0.0, Method: Composition-based stats. Identities = 205/740 (27%), Positives = 331/740 (44%), Gaps = 67/740 (9%) Query: 239 YGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGS 298 Y + + LP +++YGI E R + + + ++ D + NN + + + Sbjct: 189 YSDQYLQISARLPS-DYIYGIGEQVHK-RFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQT 246 Query: 299 VPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSE 358 + + + + G+F +N+ P + + Sbjct: 247 FFMCIEDTSGKSFGVFLMNSNAME----------------------IFIQPTPIVTYRVT 284 Query: 359 SGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDD 418 GI+D +++LG + V +QY L G A+P ++LG+ SRWNY+ V EV + + Sbjct: 285 GGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNRE 344 Query: 419 HNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIK-----V 473 +P D DI++ + K+ FT+D F ++ L +K V I+DP I Sbjct: 345 AGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRAN 404 Query: 474 DSGYRVHEELRNHGLYVKTRDGS-DYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEG 532 + Y +E +++ DGS G WPG YPDFTNP WW+N S + Sbjct: 405 GTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSI--FHQ 462 Query: 533 SAPNLYVWNDMNEPSVFNGP-------------------------EVTMLKDAVHYGGWE 567 +W DMNE S F T+ DAV G + Sbjct: 463 EVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWG-K 521 Query: 568 HRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLK 627 D+H++YG + +AT + Q+ +R F+L+R+ F+GS R A W GDNTA W+ ++ Sbjct: 522 QYDVHSLYGYSMAIATEQAV-QKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQME 580 Query: 628 ISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPW 687 SI L +L G+ GAD+ GF EL RW Q+GA+ PF R H ++P Sbjct: 581 WSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPA 640 Query: 688 LLAS--QYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQ 745 + R L RY+LLPF YTLFY+AH G V RP+ ++ ED +++ + + Sbjct: 641 FFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTE 700 Query: 746 FMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHG-PQTLYLPVTLSSIPVFQ 804 F+ G ALLI PV GA V Y+P + +WYD +S K Q + + + I + Sbjct: 701 FLWGPALLITPVLKQGADTVSAYIP--DAIWYDYESGAKRPWRKQRVDMYLPADKIGLHL 758 Query: 805 RGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRR 864 RGG I+P ++ + +P+ L VAL TA+G+ F DDG T + ++L Sbjct: 759 RGGYIIPI-QEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYT 817 Query: 865 FSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGS--PESRLSFQHDPE 922 FS S +TL T + + V I+G V + + + +F +D Sbjct: 818 FSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDAS 877 Query: 923 TSVLILRKPGVSVASDWSIH 942 VL++ +++ ++S+ Sbjct: 878 NQVLLIADLKLNLGRNFSVQ 897 >5KZW-A nrPDB Length = 874 Score = 703 bits (1815), Expect = 0.0, Method: Composition-based stats. Identities = 234/731 (32%), Positives = 343/731 (46%), Gaps = 93/731 (12%) Query: 246 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAH 305 L SLP +++ G+ EH L L + L+N D+ N LYGS P LA Sbjct: 170 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 223 Query: 306 SFH-RDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDV 364 G+F LN+ V + P + W S GI+DV Sbjct: 224 EDGGSAHGVFLLNSNAMDVVL----------------------QPSPALSWRSTGGILDV 261 Query: 365 FLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCD 424 ++ LGP V +QY + G +PP + LG+H RW Y A +V + + P D Sbjct: 262 YIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLD 321 Query: 425 VIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDS---GYRVHE 481 V W D+++ D +R FT++ F M++ L R+ + IVDP I YR ++ Sbjct: 322 VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYD 381 Query: 482 ELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWN 541 E G+++ G G WPGS ++PDFTNP AWW +M + + P +W Sbjct: 382 EGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAE--FHDQVPFDGMWI 439 Query: 542 DMNEPSVFNGPEVTMLKDA------------------------VHYGGWEHRDIHNIYGL 577 DMNEPS F + H H ++HN+YGL Sbjct: 440 DMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGL 499 Query: 578 YVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLA 637 +A+ L++ G RPFV+SR+ F+G R+ WTGD + W+ L S+P L Sbjct: 500 TEAIASHRALVKARGT--RPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFN 557 Query: 638 LVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAI 697 L+G+ GADV GF N EL VRW Q+GA+ PF R H L + +EP+ + Q A+ Sbjct: 558 LLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAM 617 Query: 698 RDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPV 757 R AL RY+LLP YTLF+QAH G V RPL++++P+D ST++++ Q + G+ALLI PV Sbjct: 618 RKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPV 677 Query: 758 SDAGAHGVQVYLPGQEEVWYDIQSY------------------QKHHGPQTLYLPVTLSS 799 AG V Y P WYD+Q+ H Q + LP L + Sbjct: 678 LQAGKAEVTGYFPLG--TWYDLQTVPIEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDT 735 Query: 800 IPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHE 859 I V R G I+P +++ + P+ L VAL+ G A+GELF DDG + R Sbjct: 736 INVHLRAGYIIPLQGPGLTTTE-SRQQPMALAVALTKGGEARGELFWDDGESLEVLERGA 794 Query: 860 F----LLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRL 915 + L R + + LV +++ G + +++V ++G VL + G P S Sbjct: 795 YTQVIFLARNNTIVNELVRVTSEGAG-----LQLQKVTVLGVATAPQQVL-SNGVPVS-- 846 Query: 916 SFQHDPETSVL 926 +F + P+T VL Sbjct: 847 NFTYSPDTKVL 857 >3TOP-A nrPDB Length = 908 Score = 652 bits (1681), Expect = 0.0, Method: Composition-based stats. Identities = 211/846 (24%), Positives = 344/846 (40%), Gaps = 118/846 (13%) Query: 155 PFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDP---AEGNGAQPEATPGD---G 208 P RLD ++ + ++ F+ + E P + PE D Sbjct: 86 PLRLD--------VTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTPEGQLYDVLIK 137 Query: 209 DKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRL 268 P + + + W+ + S + + + LP ++YG E Sbjct: 138 KNPFGIEIRRKSTGTIIWDSQLLGFTFSDMF----IRISTRLPSK-YLYGFGETEHR-SY 191 Query: 269 KVTEGGEPYRLYNLDVFQ-YELNNPMALYGSVPVLLA-HSFHRDLGIFWLNAAETWVDIS 326 + + +++ D Y+ N+ YG P + G+ LN+ V Sbjct: 192 RRDLEWHTWGMFSRDQPPGYKKNS----YGVHPYYMGLEEDGSAHGVLLLNSNAMDVTF- 246 Query: 327 SNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQ 386 P + + + G++D ++ LGP+ V +QY L G Sbjct: 247 ---------------------QPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRP 285 Query: 387 ALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRF 446 + P +SLG+ R+ Y++++++ + +P DV + DI++ + + FT P F Sbjct: 286 VMVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-F 344 Query: 447 PQPLNMLEHLASKRRKLVAIVDPHIKVDSG--YRVHEELRNHGLYVKTR-DGSDYEGWCW 503 ++ + + +++ I+DP I + Y +++K DG G W Sbjct: 345 AGFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVW 404 Query: 504 P---------------------GSASYPDFTNPRMRAWWSNMFSFD-----NYEGSAPNL 537 P ++PDF WW N E S Sbjct: 405 PDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFD 464 Query: 538 YVWNDMNEPSVF-NGPEVTMLKDAVHYGG------------------------------- 565 +W DMNEPS F NG +DA Sbjct: 465 GMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSL 524 Query: 566 WEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDH 625 +H ++HN+YG T + + + +G +R V++R+ F S R+ W GDNTA WD Sbjct: 525 VQHYNVHNLYGWSQTRPTYEAVQEVTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQ 582 Query: 626 LKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRRE 685 LK SI + +L G+S+ GAD+ GFF++ E E+ VRW Q+GA+ PF R H + T R++ Sbjct: 583 LKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQD 642 Query: 686 PWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQ 745 P + + R L RY+LLP+ YTL ++AH EG V+RPL ++ D T+ I+ Q Sbjct: 643 PVSWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQ 702 Query: 746 FMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSY-QKHHGPQTLYLPVTLSSIPVFQ 804 F+LG A L+ PV + A V Y P WYD + + + LP L I + Sbjct: 703 FLLGPAFLVSPVLERNARNVTAYFPR--ARWYDYYTGVDINARGEWKTLPAPLDHINLHV 760 Query: 805 RGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRR 864 RGG I+P W ++ + + +AL +GTA G LF DDG + + + + L Sbjct: 761 RGGYILP-WQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLAS 819 Query: 865 FSFSGSTLVSSSADPKGHLET-PIWIERVVIMGAGK-PAAVVLQTKGSPESRLSFQHDPE 922 FS S +T+ S T P+ + + I G G P V + SF +DP Sbjct: 820 FSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPT 879 Query: 923 TSVLIL 928 T VL + Sbjct: 880 TQVLSI 885 >3WEN-A nrPDB Length = 913 Score = 651 bits (1680), Expect = 0.0, Method: Composition-based stats. Identities = 217/754 (28%), Positives = 333/754 (44%), Gaps = 85/754 (11%) Query: 239 YGPTSVGLDFSLPGME-HVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYG 297 Y + L SLP + H+YG+ EH + L+N D+ + N + LYG Sbjct: 189 YKDQYLQLSSSLPAQQAHLYGLGEHTKPTFQ--LAHNQILTLWNADIASF--NRDLNLYG 244 Query: 298 SVPVLLAHSF----HRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDI 353 S P + G+F LN+ V+ + I Sbjct: 245 SHPFYMDVRSSPMVGSTHGVFLLNSNGMDVEYTG-----------------------DRI 281 Query: 354 RWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVD 413 + GIID+++ G + V QY L G A P ++ G+HQ RW YRD ++ V Sbjct: 282 TYKVIGGIIDLYIFAGRTPEMVLDQYTKLIGRPAPMPYWAFGFHQCRWGYRDVNEIETVV 341 Query: 414 QGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFP--QPLNMLEHLASKRRKLVAIVDPHI 471 + + +P +V+W DI++ D + FT DP FP + + L ++ V I+DP I Sbjct: 342 DKYAEARIPLEVMWTDIDYMDAFKDFTLDPVHFPLDKMQQFVTKLHRNGQRYVPILDPGI 401 Query: 472 KVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYE 531 + Y +++K RDG+ Y G WPG YPDF +P R++W + + Sbjct: 402 NTNKSYGTFIRGMQSNVFIK-RDGNPYLGSVWPGPVYYPDFLDPAARSFWVDEIK--RFR 458 Query: 532 GSAPNLYVWNDMNEPSVF-----------NGPEV--------------TMLKDAVHYGGW 566 P +W DMNE S F + P T+ A+HYG Sbjct: 459 DILPIDGIWIDMNEASNFITSAPTPGSTLDNPPYKINNSGGRVPINSKTIPATAMHYGNV 518 Query: 567 EHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHL 626 + HN+YG AT + L++ S ERPF+LSR+ F+GS ++ A WTGDN A WD L Sbjct: 519 TEYNAHNLYGFLESQATREALVRTS--NERPFLLSRSTFAGSGKYTAHWTGDNAARWDDL 576 Query: 627 KISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREP 686 + SIP L+ L G+ GAD+ GF ++ EL RW Q+GA+ PF R H+ DT +E Sbjct: 577 QYSIPTMLNFGLFGMPMIGADICGFAESTTEELCRRWIQLGAFYPFSRDHSARDTTHQEL 636 Query: 687 WLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQF 746 +L S A R L RY LLP++YTL Y A+ G P+ RPL+ +P+D++T+ I QF Sbjct: 637 YLWESVAASA-RTVLGLRYQLLPYYYTLMYDANLRGIPIARPLFFTFPDDVATYGISSQF 695 Query: 747 MLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKH---HGPQTLYLPVTLSSIPVF 803 ++G +++ PV GA V Y P W+ + +Y + L I V Sbjct: 696 LIGRGIMVSPVLQPGAVSVNAYFPRGN--WFSLFNYTSSVSVSAGTYVSLSAPPDHINVH 753 Query: 804 QRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQ--TRHEFL 861 G IV ++ + P L V +S + GELFLD+G + L Sbjct: 754 IHEGNIVAMQGE-AMTTQAARSTPFHLLVVMSDHVASTGELFLDNGIEMDIGGPGGKWTL 812 Query: 862 LRRFSFSG--STLVSSSADPKGHLETPIWI-ERVVIMGAGKPA-----AVVLQTKGSPES 913 +R F+ SG + +SS +G+ + W+ +++ I+G + V Sbjct: 813 VRFFAESGINNLTISSEVVNRGYAMSQRWVMDKITILGLKRRVRIKEYTVQKDAGAIKIK 872 Query: 914 RLSFQHDPETS----VLILRKPGVSVASDWSIHL 943 L + V ++ V + + L Sbjct: 873 GLGLRTSSHNQGGFVVSVISDLRQLVGQAFKLEL 906 >5DJW-A nrPDB Length = 697 Score = 643 bits (1658), Expect = 0.0, Method: Composition-based stats. Identities = 217/645 (33%), Positives = 333/645 (51%), Gaps = 52/645 (8%) Query: 247 DFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHS 306 ++P +YG E SL G+ +L+N D Y ++ LY S P ++ Sbjct: 55 SLTVPEGTSIYGGGEVTGSL----LRNGKTIKLWNTDSGAYGVDKGTRLYQSHPWMMGVR 110 Query: 307 FHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFL 366 +D F + TW S+T K I SE VF+ Sbjct: 111 --KDGTAFGILFDTTWKAELSSTDEK--------------------IELKSEGIPFRVFI 148 Query: 367 MLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVI 426 + S V R + LTGT + P ++LGY Q R++Y ++ V+E+ F +PCDVI Sbjct: 149 IDRESPQAVIRGLSELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFRLKRIPCDVI 208 Query: 427 WLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNH 486 W+DI++ DG R FT++P FP P + L + ++DP KVD Y V++ + Sbjct: 209 WMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIRGFHSAWMIDPGAKVDPNYFVYKSGTEN 268 Query: 487 GLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEP 546 ++VKT DG ++ G WPG+A++PDFT+P++ WW N++ +G VWND+NEP Sbjct: 269 DVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQGVDG---VWNDVNEP 325 Query: 547 SVFNGPEVTMLKDAVHYGGWE-----HRDIHNIYGLYVHMATADGLIQRSGGIERPFVLS 601 + + P TM +D +H GG + H HN+YG + A+ +G++ + +RPF+L+ Sbjct: 326 QINDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGFLMVKASREGILD-ARPEKRPFILT 384 Query: 602 RAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLV 661 R+ F G QR+ A WTGDN + WDHLK+S+PM L+L L G F GAD+GGF N + +L Sbjct: 385 RSNFLGGQRYAATWTGDNGSCWDHLKMSVPMSLTLGLSGQPFSGADIGGFLFNADADLFG 444 Query: 662 RWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKE 721 W GA+ PF R HA T +EPW+ + +DA R AL +RY LLP++YTL ++A Sbjct: 445 NWIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASRIALERRYILLPYFYTLLHEASTN 504 Query: 722 GFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQS 781 G P+MRP++ P+D+S + E+ F++GD LLI P A Q LP + +W ++ Sbjct: 505 GMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIP-----AFANQPALP--KGIWKELSL 557 Query: 782 YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQ 841 + G Q + RGG I+P ++ +++ D P+TL V L QG A Sbjct: 558 VE---GDQNDKYQAKMK-----IRGGAIIPTGKIIQNTTENSLD-PLTLLVCLDEQGKAS 608 Query: 842 GELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSS-ADPKGHLET 885 G ++ D G ++Y+ LL+ + V+ G T Sbjct: 609 GNMYWDAGDGWSYKKGDYSLLQFVAERNGDKVTVKLTKKTGKYNT 653 >6JR6-A nrPDB Length = 838 Score = 618 bits (1594), Expect = e-177, Method: Composition-based stats. Identities = 172/628 (27%), Positives = 281/628 (44%), Gaps = 52/628 (8%) Query: 243 SVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVL 302 + + L E +G+ E + +L + G Y+++N D Y +N LY S+P Sbjct: 145 KIRTNKVLRNDEQFFGLGEKSGNLNRR----GSAYKMWNSDQPCYGVNED-PLYKSIPFF 199 Query: 303 LAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGII 362 ++ + GIF+ N +T S + + + +G + Sbjct: 200 MSSYRY---GIFFDNTYKTEFKFGSESNDYY--------------------SFEAPAGQM 236 Query: 363 DVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMP 422 + M G ++ + Y +LTG +PP ++LG+ Q R +Y E E+ F +P Sbjct: 237 VYYFMFGNDYKEIIQNYIALTGKPIMPPKWALGFSQCRGDYTREDQAREIAAEFRKRKIP 296 Query: 423 CDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEE 482 CD+I+ DI +G + F W + P M++ L+ K++ DP I + + E Sbjct: 297 CDIIYQDIGWTEGLQDFDWRKNNYNNPKGMVKDLSDMGFKMIVSQDPVISQANQQQWKEA 356 Query: 483 LRNHGLYVKTRDGSDYEG-WCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWN 541 L R G Y+ W W G+ DFT P + WW + +G W Sbjct: 357 DALGHLVKDVRTGKSYDMPWPWGGNCGVVDFTKPEVADWWGSYQQKPLNDGV---RGFWT 413 Query: 542 DMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLS 601 DM EP+ N V L H G H +IHN+YG + + + +R F ++ Sbjct: 414 DMGEPAWSNEDAVDRLNMKHHLG--MHNEIHNVYGFTWDKVVTEQFYKHN-PNKRIFQMT 470 Query: 602 RAFFSGSQRFGAVWTGDNTA------EWDHLKISIPMCLSLALVGLSFCGADVGGFFKNP 655 RA ++G QR+ W+GD+ W + IP+ LS + + F D+ G+ + Sbjct: 471 RAAYAGLQRYTFGWSGDSGNGSNVLDGWKQMANQIPVGLSAGMGLIPFWTCDISGYCGDI 530 Query: 656 E-----PELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPF 710 + EL VRW Q G + P RAH H EPW ++ ++ R ++ +Y L P+ Sbjct: 531 KDYDAMAELYVRWLQFGVFTPLSRAH-HEGGNAVEPWKFGTEAENISRKSIELKYKLFPY 589 Query: 711 WYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLP 770 YT +AH G P+MR L ++YP D TF + QF++G LL+ PV + GA VYLP Sbjct: 590 LYTYAREAHDTGLPIMRALLLEYPNDKETFKLNGQFLVGKELLVAPVVEQGAVTKDVYLP 649 Query: 771 GQEEVWYDIQSYQ-KHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPIT 829 E W D + + K+ G Q + + L++IPVF + G+I+P+ V + D K P+T Sbjct: 650 EGE--WIDFNNCKTKYKGEQWITVDAPLNTIPVFVKKGSIIPQMP-VMQYIDEKKVYPVT 706 Query: 830 LFVALSP-QGTAQGELFLDDGHTFNYQT 856 + + DDG + +Y+ Sbjct: 707 FDIFPGNLNKETSFTFYEDDGESRDYER 734 >2G3M-A nrPDB Length = 693 Score = 579 bits (1491), Expect = e-165, Method: Composition-based stats. Identities = 176/604 (29%), Positives = 286/604 (47%), Gaps = 66/604 (10%) Query: 242 TSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPV 301 V ++ SL EH+ G+ E A L K + Y +YN+D Y+ LY S+P+ Sbjct: 50 NKVIVEKSLDLKEHIIGLGEKAFELDRK----RKRYVMYNVDAGAYKKYQD-PLYVSIPL 104 Query: 302 LLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGI 361 ++ G F+ +A++ D+ K + D Sbjct: 105 FISVKDGVATGYFFNSASKVIFDVGLEEYDKVIVTIPEDS-------------------- 144 Query: 362 IDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNM 421 ++ +++ GP + DV +Y LTG LPP+++ GY SR++Y + V+E+ Sbjct: 145 VEFYVIEGPRIEDVLEKYTELTGKPFLPPMWAFGYMISRYSYYPQDKVVELVDIMQKEGF 204 Query: 422 PCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHE 481 ++LDI + D + FTW P RFP+P +++ L + KL+ IVD I+VD Y Sbjct: 205 RVAGVFLDIHYMDSYKLFTWHPYRFPEPKKLIDELHKRNVKLITIVDHGIRVDQNYSPF- 263 Query: 482 ELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWN 541 L G + + G + G WPG+ YPDF R WW+ + S +G +W Sbjct: 264 -LSGMGKFCEIESGELFVGKMWPGTTVYPDFFREDTREWWAGLISEWLSQGVDG---IWL 319 Query: 542 DMNEPSVFNGPEV-------------------TMLKDAVHY---GGWEHRDIHNIYGLYV 579 DMNEP+ F+ T + VHY +H + N Y LY Sbjct: 320 DMNEPTDFSRAIEIRDVLSSLPVQFRDDRLVTTFPDNVVHYLRGKRVKHEKVRNAYPLYE 379 Query: 580 HMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALV 639 MAT G R+ F+LSRA ++G QR+ +WTGDNT WD LK+ + + L L++ Sbjct: 380 AMATFKGF--RTSHRNEIFILSRAGYAGIQRYAFIWTGDNTPSWDDLKLQLQLVLGLSIS 437 Query: 640 GLSFCGADVGGFFKNPEPE------LLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQY 693 G+ F G D+GGF E LLV++Y + + PF+R+H D EP L Y Sbjct: 438 GVPFVGCDIGGFQGRNFAEIDNSMDLLVKYYALALFFPFYRSHKATDGIDTEPVFLPDYY 497 Query: 694 QDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALL 753 ++ +++ + RY LP+ Y+L +A ++G PV+RPL+ ++ +D + IED++M+G LL Sbjct: 498 KEKVKEIVELRYKFLPYIYSLALEASEKGHPVIRPLFYEFQDDDDMYRIEDEYMVGKYLL 557 Query: 754 IHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRW 813 P+ + V LP + WY+ + + +G + + +P++ R G+I+P Sbjct: 558 YAPIV-SKEESRLVTLPRGK--WYNYWNGEIINGKSVVK---STHELPIYLREGSIIPLE 611 Query: 814 MRVR 817 Sbjct: 612 GDEL 615 >3POC-A nrPDB Length = 666 Score = 556 bits (1432), Expect = e-158, Method: Composition-based stats. Identities = 172/686 (25%), Positives = 308/686 (44%), Gaps = 86/686 (12%) Query: 222 EPGAWEETFKTHSDSKPYG--PTSVGLDFS--LPGMEHVYGIPEHADSLRLKVTEGGEPY 277 + A E +T ++ PYG G F+ + + VYG+ E + + Sbjct: 15 DTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGINKRGYCY---- 70 Query: 278 RLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGK 337 + N + +LYG+ ++ G+F+ ++ DI Sbjct: 71 -ISNCTDDPIHTEDKRSLYGAHNFIIVSGK-TTFGLFFDYPSKLTFDI------------ 116 Query: 338 MLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYH 397 G T ++ E+ +D++++ G + +D+ +Q+ + G +PP F+ G+ Sbjct: 117 --------GYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFG 168 Query: 398 QSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLA 457 QSRW Y + D V +G+ ++++P D+I++DI++ + FT + FP ++ + Sbjct: 169 QSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMK 228 Query: 458 SKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRM 517 + +L+ I+D +KV+ GY V+EE + + K DGSD+ WPG +PD NP Sbjct: 229 DQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEA 288 Query: 518 RAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPE------------------------ 553 R W+ + + F +G WN MNEP++F E Sbjct: 289 RKWFGDKYRFLIDQGIEGF---WNAMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWA 345 Query: 554 --------VTMLKD------AVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFV 599 V +D V+ H +HN++G + A + +R +R + Sbjct: 346 MQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAF-ERIDPEKRFLM 404 Query: 600 LSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPEL 659 SR+ + G R+G +W GDN + W H+ +++ M SL + G + GAD+GGF + +L Sbjct: 405 FSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDL 464 Query: 660 LVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAH 719 L+R+ +G + P R HA T +E + + R + RY L+P+ Y+ + +A Sbjct: 465 LLRFLALGVFTPLMRDHAAEGTREQE--CYQFENIEDFRSVINARYRLVPYLYSEYMKAA 522 Query: 720 KEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWY-- 777 +PL YP+D +EDQ MLG+ ++I PV + A G VYLP EE+ + Sbjct: 523 LNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLP--EEMKFIK 580 Query: 778 ---DIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVAL 834 D ++ Y+ V L+ +P+F R G +P V +++C+KD + Sbjct: 581 FMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIP----VAEAAECVKDIDTENMQLI 636 Query: 835 SPQGTAQGELFLDDGHTFNYQTRHEF 860 +G++ L+ DDG +Y + + Sbjct: 637 GYEGSSY-TLYEDDGIHKDYDKKENY 661 >1XSK-A nrPDB Length = 778 Score = 543 bits (1398), Expect = e-154, Method: Composition-based stats. Identities = 157/668 (23%), Positives = 260/668 (38%), Gaps = 85/668 (12%) Query: 248 FSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSF 307 L E VYG+ E +L G+ +N D + Y ++P + + Sbjct: 154 LDLGVGETVYGLGERFTAL----VRNGQTVETWNRD----GGTSTEQAYKNIPFYMTNRG 205 Query: 308 HRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLM 367 + G+ + ++ S K +++ ES ++ F++ Sbjct: 206 Y---GVLVNHPQCVSFEVGSEKVSK--------------------VQFSVESEYLEYFVI 242 Query: 368 LGPSVFDVFRQYASLTGTQALPPLFSLGYHQ--SRWNYRDEADVLEVDQGFDDHNMPCDV 425 GP+ V +Y TG ALPP +S G S DEA V G + N+P V Sbjct: 243 DGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAERNLPLHV 302 Query: 426 IWLDIEHADGKR--YFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEEL 483 D + F WDP FP P M+ L +K K+ ++P+I S V +EL Sbjct: 303 FHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRRLKAKGLKICVWINPYIGQKS--PVFKEL 360 Query: 484 RNHGLYVKTRDGSDYEGWCW-PGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWND 542 + G +K DGS ++ W PG A Y DFTNP W+++ Sbjct: 361 QEKGYLLKRPDGSLWQWDKWQPGLAIY-DFTNPDACKWYADKLKGL------------VA 407 Query: 543 MNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSR 602 M + D + G + + +HN Y + +++ + G E + +R Sbjct: 408 MGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELV-WNVLKDTVGEEEAVLFAR 466 Query: 603 AFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVR 662 + G+Q+F W GD A ++ + S+ LS+ L G F D+GGF + R Sbjct: 467 SASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTAPAHVYKR 526 Query: 663 WYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEG 722 W G R H R PW + D +R + ++P+ Y +A+ G Sbjct: 527 WCAFGLLSSHSRLHGSKSY--RVPWAYDDESCDVVRFFTQLKCRMMPYLYREAARANARG 584 Query: 723 FPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSY 782 P+MR + +++P+D + ++ Q+MLGD +++ PV A VQ YLP E W + Sbjct: 585 TPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTE-AGDVQFYLP--EGRWTHLWHN 641 Query: 783 QKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQG 842 + G + S+PV+ R T++ +R + +GTA Sbjct: 642 DELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRPD------------YVWHEGTA-- 687 Query: 843 ELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAA 902 H FN Q HE + + GS + + A G+ + + GAG+ Sbjct: 688 ------FHLFNLQDGHEAVCEVPAADGSVIFTLKAARTGNT--------ITVTGAGEAKN 733 Query: 903 VVLQTKGS 910 L + Sbjct: 734 WTLCLRNV 741 >5I24-A nrPDB Length = 836 Score = 515 bits (1325), Expect = e-146, Method: Composition-based stats. Identities = 168/651 (25%), Positives = 284/651 (43%), Gaps = 61/651 (9%) Query: 227 EETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQ 286 E F+ ++D + F L E + G + + + G+ + LYN + Sbjct: 109 ESGFQVNTD-------KINFRFYLSPGEKILGGGQRILGMDRR----GQRFPLYNRAHYG 157 Query: 287 YELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSG 346 Y ++ +Y +P +++ + + + N+A +DI G Sbjct: 158 YS-DHSGQMYFGLPAIMSSKQYILV---FDNSASGAMDI--------------------G 193 Query: 347 ETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDE 406 +T ++ ++SG L+ G S + + +TG Q LPP ++LG SR+ YR E Sbjct: 194 KTESDILQLEAKSGRSAYILVAGNSYPSLIENFTQVTGRQPLPPRWALGSFASRFGYRSE 253 Query: 407 ADVLEVDQGFDDHNMPCDVIWLDIEHA--DGKRY---FTWDPTRFPQPLNMLEHLASKRR 461 A+ Q + + P D I LD+ D K + WD FP PL+M+ + Sbjct: 254 AETRATVQKYKTEDFPLDTIVLDLYWFGKDIKGHMGNLDWDKENFPTPLDMMADFKQQGV 313 Query: 462 KLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWW 521 K V I +P + + S R + ++ L K G + G+ D + W+ Sbjct: 314 KTVLITEPFV-LTSSKRWDDAVKAKAL-AKDPQGQPKAFELYFGNGGIIDVFSKEGSRWF 371 Query: 522 SNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHM 581 S+++ + +G A W D+ EP + +D H G + +HN YG Sbjct: 372 SSIYKDLSKQGVAG---WWGDLGEPEMH-------PEDTQHAIG-DADTVHNAYGHRWAE 420 Query: 582 ATADGLIQRSGGIERPFVLSRAFFSGSQRFGAV-WTGDNTAEWDHLKISIPMCLSLALVG 640 + + RPF++ RA F GSQR+G + WTGD + W L + + L ++L+G Sbjct: 421 MLYQQQLDQ-FPELRPFIMMRAGFVGSQRYGMIPWTGDVSRTWGGLASQVELALQMSLLG 479 Query: 641 LSFCGADVGGFF--KNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIR 698 + +D+GGF + + E+ +RW Q G +QP +R H D EP + + +R Sbjct: 480 FGYIHSDLGGFADGETLDKEMYIRWLQYGVFQPVYRPHGQ-DHIPSEPVFQDEETKAILR 538 Query: 699 DALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVS 758 + RY +LP+ YT YQ G P+MRPL+ ++ + + + GD+LL+ P++ Sbjct: 539 PLVKLRYRMLPYIYTAAYQNTLTGMPLMRPLFFSDEKNPALIDNKTSYFWGDSLLVTPIT 598 Query: 759 DAGAHGVQVYLPGQEEVWYDIQSYQKHH-GPQTLYLPVTLSSIPVFQRGGTIVPRWMRVR 817 AG V + P + VW+D ++ L LP L +IPV + G +P V Sbjct: 599 QAGVESVSI--PAPKGVWFDFWKDTRYQTDGAPLTLPTDLHTIPVLVKAGAFMPYVPAVS 656 Query: 818 RSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFS 868 + D D + A + AQGE+F DDG N R++F L + Sbjct: 657 TTEDYRSDSLEIHYYADASVPLAQGEIFEDDGKDPNSIKRNQFDLLTLQAT 707 >5I0E-B nrPDB Length = 733 Score = 500 bits (1288), Expect = e-141, Method: Composition-based stats. Identities = 146/611 (23%), Positives = 231/611 (37%), Gaps = 76/611 (12%) Query: 240 GPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPM-ALYGS 298 G V + G EHV G E D L + RL ++ QY+ Y Sbjct: 159 GTHRVKFALRIEGDEHVVGFGERYDQLDQR------GLRLDSVVFEQYKAQGKHHRTYLP 212 Query: 299 VPV-LLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMS 357 +P + + R G TW D+++ + + L + D+ + + Sbjct: 213 MPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILI--------------EVDLGFEA 258 Query: 358 ESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFD 417 E + S DV + + G A P + G S + ++ V+E Sbjct: 259 EKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHR 318 Query: 418 DHNMPCDVI----WLDIEHADGKRYFTWDPTR----------------FPQPLNMLEHLA 457 + +P V+ W D E R + P + +P P M+ L Sbjct: 319 NEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELH 378 Query: 458 SKRRKLVAIVDPHIKVDSGYRVH-----EELRNHGLYVKTRDGSDYE--GWCWPGSASYP 510 + +++ P K D L G VK DG+ Y+ GW +P +A P Sbjct: 379 ERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFP-NALMP 437 Query: 511 DFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRD 570 D + R WW+ + + +G E D + G + Sbjct: 438 DLSTEAGRQWWTEQRRYLVEDLDIDGFK----------TDGGEHAWGSDLRYEDGRRGDE 487 Query: 571 IHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISI 630 +N+Y V+ A A G + RS G + P SR+ F+GSQ G W GD + W+ + SI Sbjct: 488 GNNLYP--VNYARAYGDLLRSAG-KYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSI 544 Query: 631 PMCLSLALVGLSFCGADVGGFFKN-PEPELLVRWYQMGAYQPFFRAHAH-----LDTGRR 684 ++ G+ + G D+ GF PE EL R + + P + H+ L R Sbjct: 545 TAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDR 604 Query: 685 EPWLLASQYQ-----DAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMST 739 PW +A Q D R R +L P+ Q + G P+MR ++ + +D Sbjct: 605 TPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEI 664 Query: 740 FSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSS 799 ++ Q+MLGD LLI+PV+ GA YLP E W D S + G + V Sbjct: 665 WAHPRQYMLGDELLINPVTAPGATTWTTYLP--EGQWEDYWSGEVSEGGHLVTRAVGWDI 722 Query: 800 IPVFQRGGTIV 810 IPV++R G + Sbjct: 723 IPVYRRVGAAL 733 >5JOV-A nrPDB Length = 955 Score = 500 bits (1286), Expect = e-141, Method: Composition-based stats. Identities = 149/588 (25%), Positives = 249/588 (42%), Gaps = 61/588 (10%) Query: 355 WMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQ 414 W + +D + M G ++ DV Y SLTG + P +++G+ QSR Y + ++L + Sbjct: 368 WSEMTKQLDYYFMAGENMDDVISGYRSLTGKSPVMPKWAMGFWQSREKYNTQEEMLGALK 427 Query: 415 GFDDHNMPCDVIWLDIEHA----DGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPH 470 GF D +P D I LD H G F D RFP P M++ + + +++ V P Sbjct: 428 GFRDRKIPLDNIVLDWNHWPENAWGSHEF--DKARFPDPKAMVDSIHAMHARMMISVWPK 485 Query: 471 IKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPG-SASYPDFTNPRMRA-WWSNMFSFD 528 V + + +E +G + + W PG + D +P R +W M+ Sbjct: 486 FYVTTEH--FKEFDENGWMYQQSVKDSLKDWVGPGYHYGFYDAYDPDARKLFWKQMYEHY 543 Query: 529 NYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGG-------WEHRDIHNIYGLYVHM 581 W D +EP+V + D + + N Y L Sbjct: 544 Y---PLGIDAWWMDASEPNVRD------CTDLEYRKALCGPTALGSSTEFFNAYALMNAE 594 Query: 582 ATADGLIQRSGGIERPFVLSRAFFSGSQRFG-AVWTGDNTAEWDHLKISIPMCLSLALVG 640 A DG + +R F+L+R+ F+G QR+ A W+GD W+ +K I L+ A+ G Sbjct: 595 AIYDG-QRGVDNNKRVFLLTRSGFAGLQRYSTATWSGDIGTRWEDMKAQISAGLNFAMSG 653 Query: 641 LSFCGADVGGFF-----------------KNPE----PELLVRWYQMGAYQPFFRAHAHL 679 + + D+GGF +N + EL RWYQ GA+ P +RAH Sbjct: 654 IPYWTMDIGGFCVENRYVAGQKQWNATKTENADYKEWRELNTRWYQFGAFVPLYRAHGQY 713 Query: 680 DTGRREPWLLASQYQDAIRD---ALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPED 736 RE W +A + A + RY+++P+ Y+L + + +MRPL + + D Sbjct: 714 PF--REIWEIAPEGHPAYQSVVYYTKLRYNMMPYIYSLAGMTWFDDYTIMRPLVMDFTAD 771 Query: 737 MSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVT 796 I DQFM G + ++ PV G ++Y P E WYD S + G + + Sbjct: 772 AEVNDIGDQFMFGPSFMVSPVYRYGDRSREIYFPQAEG-WYDFYSGKFQAGGERKVIEAP 830 Query: 797 LSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNY-Q 855 IP++ R G I+P ++ +D + I L++ G + L+ D+G +NY Q Sbjct: 831 YERIPLYVRAGAIIPFGDDIQY-TDEKPAEHIRLYIYQGADG--EFTLYEDEGVNYNYEQ 887 Query: 856 TRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAV 903 + + ++ + TLV + +G + ++ K A Sbjct: 888 GMYAMIPMKYDEATKTLV--IGERQGEFPGMLKERTFTVVTVNKEKAQ 933 >5F7C-A nrPDB Length = 761 Score = 485 bits (1247), Expect = e-137, Method: Composition-based stats. Identities = 161/732 (21%), Positives = 293/732 (40%), Gaps = 85/732 (11%) Query: 119 LVADPPTAR----LSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARG 174 +VAD R L + + L + G Y++ ++ + R + LSV +G Sbjct: 55 MVADTAVPREEYTLIIRQYNIGITRLFLGFGEYELTDQSEMLQFS-ERIRRVPLSVEKQG 113 Query: 175 --LMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKT 232 + F R ++PA ++ P + + + A++ Sbjct: 114 GKWILFTQDGTKRAVINVEEPALDRWSELLPDPQETLDITLYPDGKREIRLAAYDHFSPP 173 Query: 233 HSDSKPYG-------PTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVF 285 D P L F E G E + L G+ L N D Sbjct: 174 RYDGLPIAFCKRTGKKERATLSFESRPDECFAGTGERFFKMDL----SGQTLFLKNQD-- 227 Query: 286 QYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGS 345 + N Y ++P L+ + G F+ A + + ++ ++ Sbjct: 228 -GQGVNNRRTYKNIPFYLSSRMY---GTFYHTCAHSKLSLAGHS---------------- 267 Query: 346 GETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRD 405 ++++S+ ++D F++ G ++ ++ R Y LTG ++PPL+S G SR Y Sbjct: 268 ----TRSVQFLSDQAMLDAFVIAGDTMEEILRGYRDLTGYPSMPPLWSFGVWMSRMTYFS 323 Query: 406 EADVLEVDQGFDDHNMPCDVIWLDIEH--ADGKRYFTWDPTRFPQPLNMLEHLASKRRKL 463 +V E+ + PCDVI LD D + ++ RFP P ++ L ++ Sbjct: 324 ADEVNEICDRMRAEHYPCDVIHLDTGWFRTDWLCEWKFNEERFPDPKGFIQRLKKNGYRV 383 Query: 464 VAIVDPHIKVDSGYRVHEELRNHGLYVKTR----DGSDYEGWCWPGSASYPDFTNPRMRA 519 P++ D+ ++ E N + T+ DGS++ + G+ DFT P+ Sbjct: 384 SLWQLPYVAEDAE-QIEEAKANEYIAPLTKQQDTDGSNFSALDYAGT---IDFTYPKATE 439 Query: 520 WWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYV 579 W+ + DM + + DAV Y G + ++N+Y L Sbjct: 440 WYKGLLKQLL------------DMGVTCIKTDFGENIHMDAV-YKGMKPELLNNLYALLY 486 Query: 580 HMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALV 639 A + + +G V +RA ++G QR+ W GD+ + WD + S+ L L Sbjct: 487 QKAAYEITKEVTG---DGIVWARAAWAGCQRYPLHWGGDSCSSWDGMAGSLKGGLHFGLS 543 Query: 640 GLSFCGADVGGFFKNPE-------PELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 G +F DV GF P ++ +RW Q G + R H T +REPW + Sbjct: 544 GFAFWSHDVPGFHTLPNFMNSIVAEDVYMRWTQFGVFTSHIRYHG---TNKREPWHYPAI 600 Query: 693 YQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL 752 ++ RYSL+P+ A + G+P+++ L + +PED + I+D++ G+ Sbjct: 601 -APLVKKWWKLRYSLIPYIIEQSKLAVESGWPLLQALILHHPEDKLCWHIDDEYYFGNDF 659 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLY-LPVTLSSIPVFQRGGTIVP 811 L+ PV ++ + +YLP E W + + ++ G + L + V L +PV+ R ++P Sbjct: 660 LVAPVMNS-ENRRDIYLP--EGQWVNFFTGERLQGGRWLKEVYVPLEEMPVYVRENAVIP 716 Query: 812 RWMRVRRSSDCM 823 + +D M Sbjct: 717 IYPEEVNCTDEM 728 >4XPS-A nrPDB Length = 720 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 165/751 (21%), Positives = 276/751 (36%), Gaps = 101/751 (13%) Query: 181 QRAPRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYG 240 +A ES D + GAQP D E + + E + Sbjct: 39 WKATVGKPESYDLLKAAGAQPNK---DALSKTEKVSFPFANGGVSLEVSGG--------- 86 Query: 241 PTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVP 300 L F L E +YG + ++ + G+ L+ V Y + + P Sbjct: 87 --KTYLRFPLQKEEQLYGFGLNFQTVHQR----GKILELH---VDHYGGKDSGRTHAPTP 137 Query: 301 VLLAHSFHRDLGIFWLNAA--ETWVDISSNTAGKTLFGKMLDYLQGSGETP--QTDIRWM 356 ++ + + G+F +A + W + + + + + Sbjct: 138 FYVSSNGY---GVFINSARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEIL 194 Query: 357 SESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGF 416 + ++V++ GP D ++Y L G LPP + LG+ Q + DV + F Sbjct: 195 VPAEGVEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDF 254 Query: 417 DDHNMPCDVIWLDIEHADGKRY---FTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKV 473 + P D + L+ K Y F+WD +R+P P + ++ + + +L ++P+I Sbjct: 255 KEKGYPLDFVGLE-PGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISP 313 Query: 474 DSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGS 533 D+ + ++E +K GS W G PDFT R + N D E Sbjct: 314 DAPF--YKE-------IKPYTGSHT---VWLGL--VPDFTMAEARKPFFNQLLKDQIERG 359 Query: 534 APNLYVWNDMNEPSVFNGPEVTMLKDAVHY-GGWEHRDIHNIYGLYVHMATADGLIQRSG 592 + + +G + + DA + G + YGL V +A+ QR Sbjct: 360 VSGYKI-------AEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQR-- 410 Query: 593 GIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFF 652 ER F L RA G F V D D + I + L + G Sbjct: 411 -NERTFGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSG--- 466 Query: 653 KNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWY 712 E +R +Q + P +A + PW D + AL R ++P+WY Sbjct: 467 -----EEWLRRFQSNVFSPMAMINAWASGTK--PWSYPEVEADVKKFAL-LRMQMMPYWY 518 Query: 713 TLFYQAHKEGFPVMRPLWVQY--------------------PEDMSTFSIEDQFMLGDAL 752 + F + H EG P R + ++ + ++ I+DQ+M GD L Sbjct: 519 SAFARYHFEGMPPFRGMGLEEGFRQDAKVEKLNKVNLEENPYAEAASKEIKDQYMAGDDL 578 Query: 753 LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPR 812 L+ P+ AG +V LP + WYD + + + L + L IPV+ R G IVP Sbjct: 579 LVAPMF-AGEKSRKVVLPKGK--WYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPM 635 Query: 813 WMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSF----S 868 + S + + L + + +L+ DDG TFNY+ + +F R S Sbjct: 636 MPALLNSPKS--NQKVDLEIRYYGNKPGEFKLYDDDGETFNYE-KGDFSWRTIRVEKDKS 692 Query: 869 GSTLVSSSADPKGHLETPIWIERVVIMGAGK 899 G S SA KG + T + +V K Sbjct: 693 GKVKGSISAAVKGKVNT---VGKVTFTAMTK 720 >5X3I-A nrPDB Length = 743 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 139/607 (22%), Positives = 220/607 (36%), Gaps = 84/607 (13%) Query: 240 GPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPM-ALYGS 298 G L + + G E D+L + E L + QY+ Y Sbjct: 170 GVHRGRFRLQLQDGDRLVGFGERYDALDQRGRE------LDAVVFEQYKAQGVHGRTYLP 223 Query: 299 VPV-LLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMS 357 +P + + G + TW + N + G+ P Sbjct: 224 MPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEV---------ALGDEP-------- 266 Query: 358 ESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFD 417 ++D+ + G V + G P + S + + V Sbjct: 267 ---VVDLAIYEGD-PATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHR 322 Query: 418 DHNMPCD-------------VIWLDIEHA---DGKR----YFTWDPT-RFPQPLNMLEHL 456 D +P IW D +A DG F++ P +P P M++ L Sbjct: 323 DLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDEL 382 Query: 457 ASKRRKLVAIVDPHIKVDSGYRVHEE----LRNHGLYVKTRDGSDYE--GWCWPGSASYP 510 ++ K++ P K + + G V DG+ Y GW +P A P Sbjct: 383 HARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFP-QALMP 441 Query: 511 DFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRD 570 D + R R WW+ + G E D V+ G + + Sbjct: 442 DLSVQRTRDWWTEKRRYLVEHFDVDGFK----------TAGGEHAWGHDLVYADGRKGDE 491 Query: 571 IHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISI 630 +N+Y VH A A G + RS G + P SRA F+GSQ G W GD + W + S+ Sbjct: 492 GNNLYP--VHYARAFGDLLRSAG-KAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSV 548 Query: 631 PMCLSLALVGLSFCGADVGGFFKN-PEPELLVRWYQMGAYQPFFRAHAHLDT-----GRR 684 L+ A G+ + G D+ GF P+ EL +R A+ P + H+ + R Sbjct: 549 TAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDR 608 Query: 685 EPWLLASQYQDAIRDALFQRY-----SLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMST 739 PW +A D LF+R+ SL+P+ + P+MRPL+ + D Sbjct: 609 TPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEI 668 Query: 740 FSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSS 799 ++ Q++LGD LLI+PV + GA YLP E W D+ + + + V L Sbjct: 669 WNHPYQYLLGDELLINPVLEPGATTWTTYLPAGE--WIDVWTGDRVPSG-LVTRDVPLEV 725 Query: 800 IPVFQRG 806 +PV+ R Sbjct: 726 VPVYCRA 732 >6DRU-A nrPDB Length = 718 Score = 406 bits (1044), Expect = e-113, Method: Composition-based stats. Identities = 148/622 (23%), Positives = 233/622 (37%), Gaps = 98/622 (15%) Query: 238 PYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYG 297 P S FS E +YG D + + + G + N Y Sbjct: 131 PGAEFSAEFSFSATPDEQIYGTGTQQDHM---INKKGSVIDMVN-----------FNSYI 176 Query: 298 SVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMS 357 PV +++ + W AE ++ R+ + Sbjct: 177 PTPVFMSNKGY---AFIWNMPAEGRMEFG-----------------------TLRTRFTA 210 Query: 358 ESGIIDVFLM--LGPSVFDVFRQ-YASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQ 414 S + +++ P +D +Q ++LTG PP FSLGY QS+ Y ++ +V + Q Sbjct: 211 ASTTLVDYVIVAAQPGDYDTLQQRISALTGRAPAPPDFSLGYIQSKLRYENQTEVELLAQ 270 Query: 415 GFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLAS-KRRKLVAIVDPHIKV 473 F D N+P +I +D + + + DP +P M + + +++A + P + Sbjct: 271 NFHDRNIPVSMIVIDYQSWAHQGDWALDPRLWPNVAQMSARVKNLTGAEMMASLWPSVAD 330 Query: 474 DSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASY-PDFTNPRMRAWWSNMFSFDNYEG 532 DS + L+ +GL TRDG W GS D TNP R + +M + Y+ Sbjct: 331 DS--VNYAALQANGLLSATRDGPGTT-DSWNGSYIRNYDSTNPSARKFLWSMLKKNYYDK 387 Query: 533 SAPNLYVWNDMNEPSVF-----NGPEVTMLKD------AVHYGGWEHRDIHNIYGLYVHM 581 N W D + N + T ++ V+Y + +Y Sbjct: 388 GIKNF--WIDQADGGALGEAYENNGQSTYIESIPFTLPNVNYAAGTQLSVGKLYPWAHQQ 445 Query: 582 ATADGLIQ----RSGGIERPFVLSRAFFSGSQRFG-AVWTGDNTAEWDHLKISIPMCLSL 636 A +G + G LSR+ + GSQRF +W+GD T+ WD L + + LS Sbjct: 446 AIEEGFRNATDTKEGSACDHVSLSRSGYIGSQRFCSMIWSGDTTSVWDTLAVQVASGLSA 505 Query: 637 ALVGLSFCGADVGGFFKNPE------------PELLVRWYQMGAYQPFFRAHAHLD---- 680 A G + D GGF + EL VRW + PF R H Sbjct: 506 AATGWGWWTVDAGGFEVDSTVWWSGNIDTPEYRELYVRWLAWTTFLPFMRTHGSRTCYFQ 565 Query: 681 ---TGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDM 737 T EPW + I + RY L + ++F Q H G +MRPL++ + + Sbjct: 566 DAYTCANEPWSYGASNTPIIVSYIHLRYQLGAYLKSIFNQFHLTGRSIMRPLYMDFEKTD 625 Query: 738 STFS---------IEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEV----WYDIQSYQK 784 S Q+M G LL+ PV+ VYLP + W + + Sbjct: 626 PKISQLVSSNSNYTTQQYMFGPRLLVSPVTLPNVTEWPVYLPQTGQNNTKPWTYWWTNET 685 Query: 785 HHGPQTLYLPVTLSSIPVFQRG 806 + G Q + +P L IPVF G Sbjct: 686 YAGGQVVKVPAPLQHIPVFHLG 707 >5AEG-A nrPDB Length = 686 Score = 386 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 118/599 (19%), Positives = 207/599 (34%), Gaps = 83/599 (13%) Query: 242 TSVGLDFSLPGMEHVYGIPEHADSLRLK------------VTEGGEPYRLYNLDVFQYEL 289 + L + +H+YG E L+ V + Y + D + Sbjct: 115 NRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAG 174 Query: 290 NNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETP 349 + + P ++ + N+ D S+ +Y + + Sbjct: 175 GDYYWTFFPQPTFVSTQKYYC---HVDNSCYMNFDFSA-----------PEYHELALWED 220 Query: 350 QTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSL-GYHQSRWNYRDEAD 408 + +R+ + + + +L G Q P + G Sbjct: 221 KATLRFEC-----------ADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQG--GTEV 267 Query: 409 VLEVDQGFDDHNMPCDVIW-LDIEH--ADGKR-----YFTWDPTRFPQPLNMLEHLASKR 460 + + + + IW D + W+ +PQ + ++ + Sbjct: 268 CQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNQEG 327 Query: 461 RKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAW 520 + +A ++P++ D + EE HG K G DY D TNP AW Sbjct: 328 VQFLAYINPYVASDK--DLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAW 385 Query: 521 WSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVH 580 + + + E D E + D + G +HN + Sbjct: 386 FKEVIKKNMIELGCGGWMA--DFGE---------YLPTDTYLHNGVSAEIMHNAWPALWA 434 Query: 581 MATADGLIQRSGGIERPFVLSRAFFSGSQRFG-AVWTGDNTAEW---DHLKISIPMCLSL 636 + L + +G + RA +GSQ++ +W GD +W D L +P LSL Sbjct: 435 KCNYEALEE-TGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSL 493 Query: 637 ALVGLSFCGADVGG----FFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQ 692 A+ G +D+GG F ELL+RW A+ P R H + W Sbjct: 494 AMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTH--EGNRPGDNWQFD-- 549 Query: 693 YQDAIRDALFQRYS-----LLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFM 747 DA A F R + L P+ K G PVMRPL++ Y +D T++++ Q++ Sbjct: 550 -GDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYL 608 Query: 748 LGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRG 806 LG +L+ PV + G +YLP E+ W + + G + + + + PVF R Sbjct: 609 LGRDILVAPVHEEGRSDWTLYLP--EDNWVHAWTGEAFRGGE-VTVNAPIGKPPVFYRA 664 >5OHS-A nrPDB Length = 672 Score = 344 bits (881), Expect = 1e-94, Method: Composition-based stats. Identities = 119/588 (20%), Positives = 202/588 (34%), Gaps = 59/588 (10%) Query: 242 TSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPV 301 + L EHV+G E ++ G + L+ + + S Sbjct: 98 NRLWLRVVAETDEHVWGGGEQMSYFDMR----GRRFPLWTSEPGVGRDKTTEITFKS--- 150 Query: 302 LLAHSFHRDLGIFWLNAAE--TWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSES 359 + G ++ TW+ ++ K + Sbjct: 151 ---DVSGKAGGDYYNTNYPQPTWL-----SSRKYALHVETSAYSVFDFRNGDFHEIEIWA 202 Query: 360 GIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDH 419 + G S D+ + G Q P + Y+ + +D + + Sbjct: 203 VPEKIEFFAGDSFADIVSALSLHFGRQPELPDWV--YNGAIIGLKDGVNSFARLEKIRAA 260 Query: 420 NMPCDVIWL-DI-------EHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHI 471 +W D A + + TR+P + LA + + + V+P++ Sbjct: 261 GTKVSGLWCEDWVGLRQTSFGARLFWDWQANDTRYPHLRQKIAELADQGIRFLGYVNPYL 320 Query: 472 KVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYE 531 VD + + G + DG DFTNP + Sbjct: 321 CVDG--PLFPVAESAGYFATDVDGKTALVDFGEFDCGVVDFTNP--------AAADWFAA 370 Query: 532 GSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRS 591 + D + D G + + +HN + A G+ R Sbjct: 371 AIIGKNML--DFGLSGWMADFGEYLPIDIKLSNGVDAKLMHNAWPTLWAEVNAKGVESRG 428 Query: 592 GGIERPFVLSRAFFSGSQRFG-AVWTGDNTAEW---DHLKISIPMCLSLALVGLSFCGAD 647 E F RA F+G Q +W G+ + ++ D L I LS L+G ++ +D Sbjct: 429 KTGEALF-FMRAGFTGVQAHCPLIWGGNQSVDFSRHDGLVTVICGALSSGLMGNAYHHSD 487 Query: 648 VGG----FFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQ 703 +GG F EL++RW +M A+ P R H G R P QD A F Sbjct: 488 IGGYTSLFGNVRTAELIMRWTEMAAFTPVMRTH----EGNR-PRDNLQIDQDETVLAHFA 542 Query: 704 RYS-----LLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVS 758 R + L P+ +L +A K G PV RPL++ Y + T++++D ++ G +L+ PV Sbjct: 543 RMTAIYVALAPYLKSLSAEAAKTGLPVQRPLFLHYENEPQTYAVQDCYLYGADMLVAPVW 602 Query: 759 DAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRG 806 AG +YLPG E W + S ++H G + + + L VF R Sbjct: 603 KAGETQRSLYLPGHGE-WVHLWSGKRHAGGRDITVETPLGEPAVFYRA 649 >3MI6-A nrPDB Length = 745 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 72/435 (16%), Positives = 120/435 (27%), Gaps = 114/435 (26%) Query: 402 NYRDEADVLEVDQGFDDHNMPCDVIWLDIEH-------ADGKRYFTWDPTRFPQ-PLNML 453 Y D + + + ++ LD + D +FP + Sbjct: 340 TYFDFNEAKLMTIVNQAKRLGIEMFVLDDGWFGHRDDDTTSLGDWFVDQRKFPDGIEHFS 399 Query: 454 EHLASKRRKLVAIVDP-HIKVDSG-YRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYP- 510 + + + K +P + VDS Y+ H + + PG + Sbjct: 400 QAVHQQGMKFGLWFEPEMVSVDSDLYQQHP-----DWLIHAPKSTPT-----PGRHQFVL 449 Query: 511 DFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEH-R 569 D P + + + S E + + W DMN + D + Sbjct: 450 DMARPEVVDYLFKLMSQ-MIESANLDYIKW-DMN-RYATEMFSSRLTSDQQLELPHRYIL 506 Query: 570 DIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRF--------GAVWTGDNTA 621 ++ +Y P VL + SG RF WT D+T Sbjct: 507 GVYQLYARLTQAY--------------PNVLFESCASGGGRFDLGMMYYAPQAWTSDDTD 552 Query: 622 EWDHLKISI--PMCLSLALVG--LSFCGADVGG------------FFKNPEPEL------ 659 + L I A++G +S D G FF + EL Sbjct: 553 AAERLLIQFGTSYGYPQAMMGAHVSAVPNDQMGRITSLKTRGAVAFFGDLGYELDITKMA 612 Query: 660 ----------------LVRWYQMGAYQ----PFFRAHAHLDTGRREPWLLASQYQDAIRD 699 + +Q G + PF G W D + Sbjct: 613 PTELDQVKKQVAFYKCYRQLFQFGKFYRIDSPFVED------GNVTSW---QVVSDDQKQ 663 Query: 700 ALFQRYSLLPFWYTLFYQAHKEG-FPVMRPLWVQYPEDMSTFSIEDQFMLGDALL----- 753 A+ RY LL + + + +G P R Q +D ST+ GD L+ Sbjct: 664 AIAARYQLLNHPNAPYTRFYFKGLRPNQR---YQINDDPSTY-------YGDELMNAGYF 713 Query: 754 IHPVSDAGAHGVQVY 768 + + G Y Sbjct: 714 VPTILADGQESKDFY 728 >5M0X-A nrPDB Length = 575 Score = 52.9 bits (125), Expect = 7e-07, Method: Composition-based stats. Identities = 30/172 (17%), Positives = 53/172 (30%), Gaps = 6/172 (3%) Query: 364 VFLMLGPSVFDVFRQYASLTGTQ--ALPPLFSLGYHQSRWNYRDEADVLEVDQGFD-DHN 420 + ++ P+ + +YA L G + A P + S ++Y + E + N Sbjct: 175 LVVLEDPNTPLLLEKYAELVGMENNARVPKHTPTGWCSWYHYFLDLTWEETLKNLKLAKN 234 Query: 421 MPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVH 480 P +V +D + + FP M + +A P V V Sbjct: 235 FPFEVFQIDDAYEKDIGDWLVTRGDFPSVEEMAKVIAENGFIPGIWTAPF-SVSETSDVF 293 Query: 481 EELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEG 532 E + VK W D + + W ++FS G Sbjct: 294 NE--HPDWVVKENGEPKMAYRNWNKKIYALDLSKDEVLNWLFDLFSSLRKMG 343 >2YFN-A nrPDB Length = 720 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 35/255 (13%), Positives = 72/255 (28%), Gaps = 60/255 (23%) Query: 385 TQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKR------- 437 L + Y ++++ + + D++ +D + GKR Sbjct: 329 RPVLINSWEAAYFD-----FTGDTIVDLAKEAASLGI--DMVVMD-DGWFGKRNDDNSSL 380 Query: 438 -YFTWDPTRFPQ-PLNMLEHLASKRRKLVAIVDP-HIKVDSG-YRVHEELRNHGLYVKTR 493 + + T+ ++ + + K ++P I DS YR H ++ + Sbjct: 381 GDWQVNETKLGGSLAELITRVHEQGMKFGIWIEPEMINEDSDLYRAHP-----DWAIRIQ 435 Query: 494 DGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPE 553 + DF+ +R + +G + DMN Sbjct: 436 GKKPVRSR----NQLLLDFSRKEVRDCVFDQICVVLDQGKIDYVKW--DMNRS------- 482 Query: 554 VTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRF-- 611 V+ G + + +Y + + P +L G RF Sbjct: 483 ----MADVYAGNLSYDYVLGVYDFMERLCSRY-----------PDLLLEGCSGGGGRFDA 527 Query: 612 ------GAVWTGDNT 620 +W DNT Sbjct: 528 GMLYYSPQIWCSDNT 542 >2VKT-A nrPDB Length = 289 Score = 36.7 bits (83), Expect = 0.052, Method: Composition-based stats. Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 17/144 (11%) Query: 20 LAYLGVCLGITLAVDRS-----NFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDAL 74 + +LGVCLG+ LAV N K D + F RP P ++D + P L Sbjct: 120 IPFLGVCLGMQLAVIEFARNCLNLKDADSTEF-------RPNA-PVPLVIDMPEHNPGNL 171 Query: 75 TVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRD 134 + + + + E L+K + E E R R+ V L+ LS G+D Sbjct: 172 GGTMRLGIRRTVFKTENSILRKLYGDVPFIE-ERHRHRFEVNPNLIKQFEQNDLSFVGQD 230 Query: 135 ---DNSVELTVAEGPYKIILTAQP 155 D + +A PY + + P Sbjct: 231 VDGDRMEIIELANHPYFVGVQFHP 254 >5OT1-A nrPDB Length = 765 Score = 36.3 bits (82), Expect = 0.064, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 42/145 (28%), Gaps = 30/145 (20%) Query: 431 EHADGKRYFTWDPT--RFPQPLNMLEHLASKRRKLVAIVDP---HIKVDSGYRVHEELRN 485 D Y+ DP + L+ + +++ P I + V E+ Sbjct: 381 HGYDTYDYYRLDPKFGTEDELREFLDEAHRRGMRVIFDFVPNHCGIGNPAFLDVWEKGNE 440 Query: 486 HGLY---------VKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPN 536 + K DGS Y GW GS + N +R + Sbjct: 441 SPYWDWFFVKKWPFKLGDGSAYVGWWGFGSLPKLNTANQEVREY------------LIGA 488 Query: 537 LYVWNDMNEPSVFNGPEVTMLKDAV 561 W + F+G V + + + Sbjct: 489 ALHWIEFG----FDGIRVDVPNEVL 509 >3HQ1-A nrPDB Length = 644 Score = 33.6 bits (75), Expect = 0.43, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 53/146 (36%), Gaps = 17/146 (11%) Query: 221 DEPGAWEETFKTHSDSKPYGPTSVG-------LDFSLPGMEHVYGIPEHADSLRLKV--- 270 + P A+ E+F H+ KP GP VG S+P + E + +RL+ Sbjct: 5 ESPDAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRY-RPFAEEVEPIRLRNRTW 63 Query: 271 -TEGGEPYRLYNLDVFQYELN---NPM--ALYGSVPVLLAHSFHRDLGIFWLNAAETWVD 324 + L+ + +PM A + LL ++++ + + +A++T D Sbjct: 64 PDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFD 123 Query: 325 ISSNTAGKTLFGKMLDYLQGSGETPQ 350 + + + P+ Sbjct: 124 FVREIIEQGAIPDDVTIQVLTQCRPE 149 >3HPX-A nrPDB Length = 425 Score = 33.2 bits (74), Expect = 0.51, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 53/146 (36%), Gaps = 17/146 (11%) Query: 221 DEPGAWEETFKTHSDSKPYGPTSVG-------LDFSLPGMEHVYGIPEHADSLRLKV--- 270 + P A+ E+F H+ KP GP VG S+P + E + +RL+ Sbjct: 5 ESPDAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRY-RPFAEEVEPIRLRNRTW 63 Query: 271 -TEGGEPYRLYNLDVFQYELN---NPM--ALYGSVPVLLAHSFHRDLGIFWLNAAETWVD 324 + L+ + +PM A + LL ++++ + + +A++T D Sbjct: 64 PDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFD 123 Query: 325 ISSNTAGKTLFGKMLDYLQGSGETPQ 350 + + + P+ Sbjct: 124 FVREIIEQGAIPDDVTIQVLTQCRPE 149 >5NIL-A nrPDB Length = 479 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 58/158 (36%), Gaps = 8/158 (5%) Query: 97 NMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPF 156 N+ + I +++ R +Y D ++A+ TAR ++ + ++T P L + F Sbjct: 145 NVGLVAITDVQNARAQY---DTVLANELTARNNLDNAVEQLRQITGNYYPELAALNVENF 201 Query: 157 RLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPEETQE 216 + D + + LL + ++ R + + +G P +T Sbjct: 202 KTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSY 261 Query: 217 KAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGME 254 K A T D G VGL FSLP + Sbjct: 262 SGSKTRGAA-----GTQYDDSNMGQNKVGLSFSLPIYQ 294 >2PFD-A nrPDB Length = 541 Score = 33.2 bits (74), Expect = 0.62, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 9/67 (13%) Query: 56 GLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRV 115 GL P +ALLD D + ++ E ++ LV+ R+ +D L P P+ R+ Sbjct: 271 GLVPLKALLDAAAFYCDKEKLFVLEEEHRIRLVVN---------RLGLDSLAPFDPKERI 321 Query: 116 PDVLVAD 122 + LV D Sbjct: 322 IEYLVPD 328 >1QD1-A nrPDB Length = 325 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 9/65 (13%) Query: 56 GLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRV 115 GL P +ALLD + + L+ + ++ LV+ R+ +D L P +P+ R+ Sbjct: 270 GLVPLKALLDAAAFYCEKENLFLLQDEHRIRLVVN---------RLGLDSLAPFKPKERI 320 Query: 116 PDVLV 120 + LV Sbjct: 321 IEYLV 325 >1A8Q-A nrPDB Length = 274 Score = 31.3 bits (69), Expect = 2.2, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 710 FWYTLFYQAHKEGFPVMRPLWV-QYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVY 768 FWY Q + G + + ED+ F I + GD + P+ G Q+ Sbjct: 180 FWYMAMAQTIEGGVRCVDAFGYTDFTEDLKKFDIPTLVVHGDDDQVVPIDATGRKSAQI- 238 Query: 769 LPGQEEVWYDIQS 781 +P E Y+ S Sbjct: 239 IPNAELKVYEGSS 251 >3UXF-A nrPDB Length = 488 Score = 30.9 bits (68), Expect = 2.8, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 48/151 (31%), Gaps = 5/151 (3%) Query: 786 HGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELF 845 + + +T S V GG + R+ V R +K + +T V + G + L Sbjct: 196 GSGRDITYTITTSIPKVDYPGGARIKRYEVVDRLDKRIKKEALTPVVKI--VGQNEVTLA 253 Query: 846 LDDGHTFNYQTRHEFLLRRFSFSGS-TLVSSSADPKGHLETPIWIE-RVVIMGAGKPAAV 903 +T + + +S A G+ ET + + A Sbjct: 254 ETTDYTLITAEGKDHNWATIQLTEEGRRKASEARYNGNGETKLQVTLNAKFDAAVNLEGD 313 Query: 904 VLQTKG-SPESRLSFQHDPETSVLILRKPGV 933 + T G P +F DP PG+ Sbjct: 314 LSNTAGLIPNDSPNFTWDPNNPGTTTDIPGI 344 >3ISR-A nrPDB Length = 293 Score = 30.5 bits (67), Expect = 3.4, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 35/109 (32%), Gaps = 9/109 (8%) Query: 725 VMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGA------HGVQVYLPGQEEVWYD 778 VM P + ++ E Q +L ++L++ P + V L E + Sbjct: 24 VMSPTTFIF--NVHALRTESQHILDESLIVTPPIEIEEFSYNSGTSRFVRLKATENTTFS 81 Query: 779 I-QSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDD 826 + + + + L ++PV G I+P R Sbjct: 82 MSYTATVDTQYKVIDQRQELETVPVVDLDGDIIPFLFPSRYCQSDKLQK 130 >3AWQ-A nrPDB Length = 415 Score = 30.5 bits (67), Expect = 3.5, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 24/71 (33%), Gaps = 2/71 (2%) Query: 435 GKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRD 494 + F W+ FP+ ++ L DP +R +E + ++ Sbjct: 295 ASQDFEWEGMAFPEGRQVVLDLYGSNHDAATWADPQEFRPERFRAWDEDSFN--FIPQGG 352 Query: 495 GSDYEGWCWPG 505 G Y G PG Sbjct: 353 GDHYLGHRCPG 363 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.125 0.344 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,260,274 Number of Sequences: 36641 Number of extensions: 1499364 Number of successful extensions: 3957 Number of sequences better than 10.0: 37 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 3600 Number of HSP's gapped (non-prelim): 84 length of query: 944 length of database: 10,336,785 effective HSP length: 106 effective length of query: 838 effective length of database: 6,452,839 effective search space: 5407479082 effective search space used: 5407479082 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 64 (29.4 bits)