BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q86WA6 (291 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2OCI-A nrPDB 530 e-151 2XUA-A nrPDB 79 3e-15 2WUG-A nrPDB 66 2e-11 3OM8-A nrPDB 64 5e-11 1XRN-A nrPDB 61 7e-10 3V1K-A nrPDB 59 2e-09 1U2E-A nrPDB 59 2e-09 3FOB-A nrPDB 59 3e-09 4G5X-A nrPDB 50 1e-06 3KXP-A nrPDB 50 1e-06 3HEA-A nrPDB 50 1e-06 5EGN-A nrPDB 48 5e-06 3V48-A nrPDB 47 9e-06 4NZZ-A nrPDB 46 2e-05 3BF8-A nrPDB 45 4e-05 2JBW-A nrPDB 44 6e-05 4FBL-A nrPDB 43 1e-04 3NWO-A nrPDB 43 2e-04 1A8S-A nrPDB 42 3e-04 3LJ5-A nrPDB 37 0.008 4RNC-A nrPDB 37 0.014 4DGQ-A nrPDB 36 0.016 1HKH-A nrPDB 35 0.036 4NVR-A nrPDB 35 0.048 5Y6Y-B nrPDB 35 0.054 3JWE-A nrPDB 33 0.14 1A8Q-A nrPDB 33 0.14 1A88-A nrPDB 33 0.16 4UHD-A nrPDB 33 0.17 1IMJ-A nrPDB 33 0.21 4IQ4-A nrPDB 32 0.34 4L7L-A nrPDB 32 0.36 1BRO-A nrPDB 32 0.37 2XMZ-A nrPDB 32 0.43 1M33-A nrPDB 31 0.64 5XKS-A nrPDB 31 0.73 3CMI-A nrPDB 30 1.8 3H7L-A nrPDB 30 1.8 3RLI-A nrPDB 30 1.8 1R3D-A nrPDB 29 1.9 6NIO-A nrPDB 29 2.2 1Q0R-A nrPDB 29 2.5 6COB-A nrPDB 28 4.8 5UNO-A nrPDB 28 5.4 1Y7H-A nrPDB 28 6.6 >2OCI-A nrPDB Length = 254 Score = 530 bits (1364), Expect = e-151, Method: Compositional matrix adjust. Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 38 SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPR 97 SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPR Sbjct: 1 SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPR 60 Query: 98 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH 157 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH Sbjct: 61 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH 120 Query: 158 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 217 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK Sbjct: 121 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 180 Query: 218 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLR 277 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLR Sbjct: 181 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLR 240 Query: 278 FADEFNKLAEDFLQ 291 FADEFNKLAEDFLQ Sbjct: 241 FADEFNKLAEDFLQ 254 >2XUA-A nrPDB Length = 266 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 68/263 (25%), Positives = 117/263 (44%), Gaps = 25/263 (9%) Query: 45 AVNGVQLHYQQTGE--GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHS 102 AVNG +LHY+ GE G+ ++L LG+ + + PQ+ L+K F V+ +D RG+GHS Sbjct: 8 AVNGTELHYRIDGERHGNAPWIVLSNSLGTDLSMWAPQVAALSKH-FRVLRYDTRGHGHS 66 Query: 103 RPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIW 162 P + E+ D + LM LK + + G S GG+T + AA++ I ++ + Sbjct: 67 EAPKGPYT---IEQLTGDVLGLMDTLKIARANFCGLSMGGLTGVALAARHADRIERVALC 123 Query: 163 GANAYVTDEDSMI-------YEGIRDVS-----KW---SERTRKPLEALYGYDYFARTCE 207 A + + + EG+ ++ +W R+P+ D F T + Sbjct: 124 NTAARIGSPEVWVPRAVKARTEGMHALADAVLPRWFTADYMEREPVVLAMIRDVFVHTDK 183 Query: 208 KWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLM 267 +G D R P ++ PAL++ G D + + + G+R ++ Sbjct: 184 ---EGYASNCEAIDAADLRPEAPGIKVPALVISGTHDLAATPAQGRELAQAIAGAR-YVE 239 Query: 268 PEGKHNLHLRFADEFNKLAEDFL 290 + H ++ AD F K DFL Sbjct: 240 LDASHISNIERADAFTKTVVDFL 262 >2WUG-A nrPDB Length = 291 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 88/291 (30%), Positives = 134/291 (46%), Gaps = 45/291 (15%) Query: 34 AFGTSVTSAKVAVNG-VQLHYQQTGEG-DHAVLLLPGMLGSGE---TDFGPQLKNLNKKL 88 F ++ A+V V+G ++LHY + G G D V+LL G G G T+F + L + Sbjct: 8 TFESTSRFAEVDVDGPLKLHYHEAGVGNDQTVVLLHGG-GPGAASWTNFSRNIAVLARH- 65 Query: 89 FTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVD-LMKALKFKKVSLLGWSDGGITALI 147 F V+A D GYGHS D+ F R A A+ L L +V L+G + GG TA+ Sbjct: 66 FHVLAVDQPGYGHS---DKRAEHGQFNRYAAMALKGLFDQLGLGRVPLVGNALGGGTAVR 122 Query: 148 AAAKYPSYIHKMVIWG-----ANAYVTDEDSMIYEGIRDVSKWS-ERTRKPLEA---LYG 198 A YP+ ++V+ G N + D EG++ +SK+S TR+ LEA + Sbjct: 123 FALDYPARAGRLVLMGPGGLSINLFAPDPT----EGVKRLSKFSVAPTRENLEAFLRVMV 178 Query: 199 YDYFARTCEKWVDGIRQFKHLPD-------------------GNICRHLLPRVQCPALIV 239 YD T E VD P+ G + R + R++ P L++ Sbjct: 179 YDKNLITPE-LVDQRFALASTPESLTATRAMGKSFAGADFEAGMMWREVY-RLRQPVLLI 236 Query: 240 HGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 G +D + P A K + ++LH+ + H + + DEFNKL +FL Sbjct: 237 WGREDRVNPLDGALVALKTIPRAQLHVFGQCGHWVQVEKFDEFNKLTIEFL 287 >3OM8-A nrPDB Length = 266 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 63/269 (23%), Positives = 107/269 (39%), Gaps = 42/269 (15%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 +G L Y+ G + +L L +G+ + QL L + F V+ +D RG+G S P Sbjct: 13 DGASLAYRLDGAAEKPLLALSNSIGTTLHMWDAQLPALTRH-FRVLRYDARGHGASSVPP 71 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANA 166 + R +D ++L+ AL+ ++ LG S GGI A P I ++V+ +A Sbjct: 72 GPYT---LARLGEDVLELLDALEVRRAHFLGLSLGGIVGQWLALHAPQRIERLVLANTSA 128 Query: 167 YVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKW------------VDGIR 214 + + ++W ER L+A + A W V+ R Sbjct: 129 W-----------LGPAAQWDERIAAVLQAEDMSETAAGFLGNWFPPALLERAEPVVERFR 177 Query: 215 -------------QFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG 261 F + D ++ R L R++ P L++ G D + H + I + G Sbjct: 178 AMLMATNRHGLAGSFAAVRDTDL-RAQLARIERPTLVIAGAYDTVTAASHGELIAASIAG 236 Query: 262 SRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 +RL +P H ++ F F FL Sbjct: 237 ARLVTLP-AVHLSNVEFPQAFEGAVLSFL 264 >1XRN-A nrPDB Length = 293 Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 72/287 (25%), Positives = 121/287 (42%), Gaps = 51/287 (17%) Query: 46 VNGVQLHYQQTGEGDHAVLLLPGMLGSGET-DFGPQLKNLNKKLFTVVAWDPRGYGHSRP 104 VNG+ ++Y+ + L+ G G + D+ L+++ K+ TV+ +D G G S Sbjct: 12 VNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQFGCGRSEE 71 Query: 105 PDRD-FPADFFERDAKDAVDLMKALKFK-----KVSLLGWSDGGITALIAAAKYPSYIHK 158 PD+ F D+ V+ +AL+ K KV L+G S GG AL A KY ++ Sbjct: 72 PDQSKFTIDY-------GVEEAEALRSKLFGNEKVFLMGSSYGGALALAYAVKYQDHLKG 124 Query: 159 MVIWGANA----YVTDEDSMIYE---------------GIRDVSKWSERTRK-------- 191 +++ G + V + + +I E G + ++ E Sbjct: 125 LIVSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEYQEAVNYFYHQHLLR 184 Query: 192 ----PLEALYGYDYFA-RTCEKWVDGIRQFK---HLPDGNICRHLLPRVQCPALIVHGEK 243 P E L +Y R + ++G QF + D +I + ++ P LI GE Sbjct: 185 SEDWPPEVLKSLEYAERRNVYRIMNGPNQFTITGTIKDWDITDK-ISAIKIPTLITVGEY 243 Query: 244 DPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 D + P A IH+ + GS LH+ + H + +NKL DF+ Sbjct: 244 DEVTPNV-ARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFI 289 >3V1K-A nrPDB Length = 286 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 74/285 (25%), Positives = 114/285 (40%), Gaps = 28/285 (9%) Query: 33 AAFGTSVTSAKVAVN-----GVQLHYQQTGEGDHAVLL-LPGMLGSGETDFGPQLKNLNK 86 A S TS V +N +HY + G G+ ++L G G +++ + Sbjct: 2 TALTESSTSKFVKINEKGFSDFNIHYNEAGNGETVIMLHGGGPGAGGWSNYYRNVGPFVD 61 Query: 87 KLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITAL 146 + V+ D G+ S D +A+ LM AL + L+G S GG TAL Sbjct: 62 AGYRVILKDSPGFNKSDAVVMDEQRGLV--NARAVKGLMDALDIDRAHLVGNSMGGATAL 119 Query: 147 IAAAKYPSYIHKMVIWGANAYVTDEDS-MIYEGIRDVSKW----SERTRKPLEALYGYDY 201 A +YP I K+++ G + M EGI+ + K S T K + ++ YD Sbjct: 120 NFALEYPDRIGKLILMGPGGLGPSMFAPMPMEGIKLLFKLYAEPSYETLKQMLQVFLYDQ 179 Query: 202 FARTCE----KWVDGIRQFKHLPDGNICRHLLP-----------RVQCPALIVHGEKDPL 246 T E +W RQ +HL + I P ++ I G D Sbjct: 180 SLITEELLQGRWEAIQRQPEHLKNFLISAQKAPLSTWDVTARLGEIKAKTFITWGRDDRF 239 Query: 247 VPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 VP H + ++ +RLH+ + ADEFN+L DFL+ Sbjct: 240 VPLDHGLKLLWNIDDARLHVFSKCGQWAQWEHADEFNRLVIDFLR 284 >1U2E-A nrPDB Length = 289 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/270 (25%), Positives = 114/270 (42%), Gaps = 36/270 (13%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGET---DFGPQLKNLNKKLFTVVAWDPRGYGHSRPP 105 +++H+ G+GD V+LL G G G T +F + L + + V+ D G+G S Sbjct: 25 LRIHFNDCGQGDETVVLLHGS-GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSV 83 Query: 106 -DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIW-G 163 + +D R K VD L K+ LLG S GG +++ K+P + K+V+ G Sbjct: 84 VNSGSRSDLNARILKSVVD---QLDIAKIHLLGNSMGGHSSVAFTLKWPERVGKLVLMGG 140 Query: 164 ANAYVTDEDSMIYEGIRDVSK-WSERTRKPLEALYGYDYFARTCEKWVDGIRQFK----- 217 ++ M EGI+ +++ + + T + L+ + D F D + + + Sbjct: 141 GTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLM--MDIFVFDTSDLTDALFEARLNNML 198 Query: 218 ----HLPDGNICRHL-------------LPRVQCPALIVHGEKDPLVPRFHADFIHKHVK 260 HL N + L L ++ LIV G D VP + + Sbjct: 199 SRRDHLE--NFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIA 256 Query: 261 GSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 GS LH+ + H AD FN+L +FL Sbjct: 257 GSELHIFRDCGHWAQWEHADAFNQLVLNFL 286 >3FOB-A nrPDB Length = 281 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 68/273 (24%), Positives = 117/273 (42%), Gaps = 39/273 (14%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 ++++Y+ G G V+L+ G SG + + Q+ L + + V+ +D RG+G S P Sbjct: 17 IEIYYEDHGTG-KPVVLIHGWPLSGRS-WEYQVPALVEAGYRVITYDRRGFGKSSQPWEG 74 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG--------------ITALIAAAKYPS 154 + D F D L++ L+ + V+L+G+S GG I ++ A P Sbjct: 75 YEYDTF---TSDLHQLLEQLELQNVTLVGFSMGGGEVARYISTYGTDRIEKVVFAGAVPP 131 Query: 155 YIHK------------MVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEA--LYGYD 200 Y++K + + + D + + E + +RT E+ LY +D Sbjct: 132 YLYKSEDHPEGALDDATIETFKSGVINDRLAFLDEFTKGFFAAGDRTDLVSESFRLYNWD 191 Query: 201 YFARTCEK-WVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP-RFHADFIHKH 258 A K +D I F R L + P LI+HG+ D VP + H+ Sbjct: 192 IAAGASPKGTLDCITAFSKTD----FRKDLEKFNIPTLIIHGDSDATVPFEYSGKLTHEA 247 Query: 259 VKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + S++ L+ G H L+ A EFN+ FL+ Sbjct: 248 IPNSKVALIKGGPHGLNATHAKEFNEALLLFLK 280 >4G5X-A nrPDB Length = 279 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 66/261 (25%), Positives = 104/261 (39%), Gaps = 41/261 (15%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSR---PPDRDFPADFF 114 EG+ A LL+ S F PQL+ K + V+A D G+G S PDR + + + Sbjct: 21 EGEGAPLLMIHGNSSSGAIFAPQLEGEIGKKWRVIAPDLPGHGKSTDAIDPDRSYSMEGY 80 Query: 115 ERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSM 174 A ++M+ L + GWS GG + A+YP + ++I G +E Sbjct: 81 ---ADAMTEVMQQLGIADAVVFGWSLGGHIGIEMIARYPE-MRGLMITGTPPVAREEVGQ 136 Query: 175 IYE-------------GIRDVSKWSERT-RKPLEALYGYDYFARTCEKWVDG------IR 214 ++ RDV ++ T +P EA D ART DG Sbjct: 137 GFKSGPDMALAGQEIFSERDVESYARSTCGEPFEASL-LDIVART-----DGRARRIMFE 190 Query: 215 QFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS----RLHLMPEG 270 +F GN R ++ Q P +V+G +P V DF+ K G+ + H++ Sbjct: 191 KFGSGTGGN-QRDIVAEAQLPIAVVNGRDEPFV---ELDFVSKVKFGNLWEGKTHVIDNA 246 Query: 271 KHNLHLRFADEFNKLAEDFLQ 291 H EF+ F++ Sbjct: 247 GHAPFREAPAEFDAYLARFIR 267 >3KXP-A nrPDB Length = 314 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 71/156 (45%), Gaps = 17/156 (10%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 S +V + + L+ ++ G G ++L + S F P + L+ + FT +A D RG+G Sbjct: 50 SRRVDIGRITLNVREKGSG--PLMLFFHGITSNSAVFEPLMIRLSDR-FTTIAVDQRGHG 106 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV 160 S P+ + A+ + A D L++ L L+G S G ++ AAAKYP + +V Sbjct: 107 LSDKPETGYEANDY---ADDIAGLIRTLARGHAILVGHSLGARNSVTAAAKYPDLVRSVV 163 Query: 161 IWGANAYVTDE-----------DSMIYEGIRDVSKW 185 Y+ E S ++E I+ V + Sbjct: 164 AIDFTPYIETEALDALEARVNAGSQLFEDIKAVEAY 199 >3HEA-A nrPDB Length = 271 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 55/275 (20%), Positives = 115/275 (41%), Gaps = 29/275 (10%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 S VA +G Q++++ G G + L + ++ Q++ L+ + + +A+D RG+G Sbjct: 1 STFVAKDGTQIYFKDWGSGKPVLFSHGWPLDADMWEY--QMEYLSSRGYRTIAFDRRGFG 58 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSY-IHKM 159 S P + + ++ A D L++ L K+V+L+G+S GG A++ S + + Sbjct: 59 RSDQP---WTGNDYDTFADDIAQLIEHLDLKEVTLVGFSMGGGDVARYIARHGSARVAGL 115 Query: 160 VIWGANAYVTDEDSMIYEGI-------------RDVSKWSERTRKPLEALYGYDYFARTC 206 V+ GA + + +G+ +D +++ P + ++ Sbjct: 116 VLLGAVTPIFGQKPDYPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINKGQVVSQGV 175 Query: 207 EKWVDGIRQFKHLPDGNIC---------RHLLPRVQCPALIVHGEKDPLVP-RFHADFIH 256 + I L C R + ++ P L++HG+ D +VP Sbjct: 176 QTQTLQIALLASLKATVDCVTAFAETDFRPDMAKIDVPTLVIHGDGDQIVPFETTGKVAA 235 Query: 257 KHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + +KG+ L + + H + A + N+ FL+ Sbjct: 236 ELIKGAELKVYKDAPHGFAVTHAQQLNEDLLAFLK 270 >5EGN-A nrPDB Length = 271 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 62/265 (23%), Positives = 105/265 (39%), Gaps = 26/265 (9%) Query: 44 VAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGP-QLKNLNKKLFTVVAWDPRGYGHS 102 V +GV+++Y GEG V L P G F N V+ D RG+G S Sbjct: 4 VENDGVKIYYDSYGEGVPIVFLHPFSTNGGIWYFQTFPFAQTNH----VIVIDHRGHGRS 59 Query: 103 RPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIW 162 P + A D V ++ ALK + +G S GG+ A+ +P + +I Sbjct: 60 DKPATGYS---IMEHADDVVAVLDALKVDRAVFVGNSIGGMIAMQLNLDHPQRVIGNLIL 116 Query: 163 G------------ANAYVTDEDSMIYEGIRD--VSKWSERTRKPLEALYGYDYFARTCEK 208 A A ++ + G+ + VS S+R R + A+ +F+ Sbjct: 117 SSGTGLGEGMPPEAGAAFQNDYIGAFGGLLEGAVSARSKRERPEILAVM-KAHFSVPSNF 175 Query: 209 WVDGIRQFKHLPDGNICRHL---LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLH 265 P+G ++ L +Q P L+V GE+D + + + ++ G+ L Sbjct: 176 PKHVFDAATADPNGVFAWNIKDRLSSIQAPTLVVAGEEDLVTTVANNQLLADNIPGAELR 235 Query: 266 LMPEGKHNLHLRFADEFNKLAEDFL 290 ++ + H L EFN+L F+ Sbjct: 236 VINDVGHFYQLERPSEFNELLRGFV 260 >3V48-A nrPDB Length = 268 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 56/242 (23%), Positives = 107/242 (44%), Gaps = 30/242 (12%) Query: 63 VLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAV 122 V+L+ G+ GSG + + PQL L ++ + VV +D RG G++ PD D+ A+ A Sbjct: 18 VVLISGLGGSG-SYWLPQLAVLEQE-YQVVCYDQRGTGNN--PD-TLAEDY--SIAQMAA 70 Query: 123 DLMKAL---KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGI 179 +L +AL + +++G + G + + A YP+ + ++ + ++ + Sbjct: 71 ELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQ-V 129 Query: 180 RDVSKWSERTRKPLEA----LYGYDYFARTCEKWV--------------DGIRQFKHLPD 221 R+ +S + +EA LY D+ A + + +R+ L Sbjct: 130 RERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKR 189 Query: 222 GNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADE 281 + H R++CP I+ D LVP + +H + S+ +MP G H ++ + Sbjct: 190 ADFSHHA-DRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPET 248 Query: 282 FN 283 FN Sbjct: 249 FN 250 >4NZZ-A nrPDB Length = 320 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 70/312 (22%), Positives = 113/312 (36%), Gaps = 53/312 (16%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFG---- 78 G H+ G ++ + VNGV LHY G+G+ + L G DF Sbjct: 18 GSHMASMTGGQQMGRGMSKQYINVNGVNLHYISKGQGELMLFL------HGFPDFSHIWR 71 Query: 79 PQLKNLNKKLFTVVAWDPRGYGHSRPPD--RDFPADFFERDAKDAVDLMKALKFKKVSLL 136 Q+ + F VA D RGY S P + D D + ++ L + +L+ Sbjct: 72 HQIDEFSND-FHTVALDLRGYNLSEKPSGLESYEIDVLVEDIRQVIE---GLGYSSCTLV 127 Query: 137 GWSDGGITALIAAAKYPSYIHKMVIW-GANAYV------TDEDS------MIYEGIRDVS 183 G A +YP Y+ K++ + G + Y T+++ M + ++V Sbjct: 128 VHDWGAGIGWTFAYRYPEYVQKLIAFNGPHPYTFMRELRTNKNQQKASEYMKWFQKQEVQ 187 Query: 184 KWSERTR-KPLEALY-------GY---DYFARTCEKWVDG--------IRQFKHLPDGNI 224 + ER L L GY D W +G R K + ++ Sbjct: 188 DYMERDNFSGLRKLVIDPGVKKGYLTADDVQAYMNSWENGSVLSMLSYYRNLKIFTEEDL 247 Query: 225 CR-HLLPR----VQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFA 279 R L P + P I+ G +DP + D I ++V +H + E H Sbjct: 248 RRKSLFPLEEEVLNIPVQIIWGNQDPTFMPENLDGIEEYVPNISVHRLAEASHAPQHEKP 307 Query: 280 DEFNKLAEDFLQ 291 E N + +FL Sbjct: 308 QEVNNVMWNFLN 319 >3BF8-A nrPDB Length = 255 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 61/240 (25%), Positives = 102/240 (42%), Gaps = 29/240 (12%) Query: 55 QTGEGDHA---VLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHS-RPPDRDFP 110 QT + H ++L+ G+ GS + + G ++L ++ D R +G S R P ++P Sbjct: 8 QTAQNQHNNSPIVLVHGLFGSLD-NLGVLARDLVND-HNIIQVDVRNHGLSPREPVMNYP 65 Query: 111 ADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV---IWGANAY 167 A A+D VD + A + K + +G S GG + A P I K+V I + + Sbjct: 66 AM-----AQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALAPDRIDKLVAIDIAPVDYH 120 Query: 168 VTDEDSMIYEGIRDVSKWSERTRKPLEALY-------GYDYFARTCEKWVDGIRQFKHLP 220 V D I+ I VS+ +TR+ A+ G F + +VDG +F Sbjct: 121 VRRHDE-IFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQF--LLKSFVDGEWRFNVPV 177 Query: 221 DGNICRHL-----LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLH 275 + H+ +P PAL + G P V + D + +R H++ H +H Sbjct: 178 LWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLLAQFPQARAHVIAGAGHWVH 237 >2JBW-A nrPDB Length = 386 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 62/232 (26%), Positives = 99/232 (42%), Gaps = 39/232 (16%) Query: 57 GEGDH-AVLLLPGMLGSGETDFGPQLKNLN-KKLFTVVAWDPRGYGHSRPPDRDFPADFF 114 G G H AV++L G+ + E F Q++NL + +D G G R A + Sbjct: 148 GPGPHPAVIMLGGLESTKEESF--QMENLVLDRGMATATFDGPGQGEMFEYKR--IAGDY 203 Query: 115 ERDAKDAVDLM---KALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDE 171 E+ VDL+ +A++ + +LG S GG AL +AA P + + WG Sbjct: 204 EKYTSAVVDLLTKLEAIRNDAIGVLGRSLGGNYALKSAACEPR-LAACISWG-------- 254 Query: 172 DSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK-HLPDGNICRHLLP 230 G D+ W T E+ + Y ++ VD + + + H+ R +L Sbjct: 255 ------GFSDLDYWDLETPLTKES---WKYVSK-----VDTLEEARLHVHAALETRDVLS 300 Query: 231 RVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGK-----HNLHLR 277 ++ CP I+HG D VP D + + V L+L+ E HNL +R Sbjct: 301 QIACPTYILHGVHDE-VPLSFVDTVLELVPAEHLNLVVEKDGDHCCHNLGIR 351 >4FBL-A nrPDB Length = 281 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 25/183 (13%) Query: 96 PRGYGHSRPPDRDFPADFFERDAKD-AVDLMKALKFKK-----VSLLGWSDGGITALIAA 149 PR GH PA+ A D D++ A+++ + + + G S GG + AA Sbjct: 84 PRLTGHG-----TTPAEMAASTASDWTADIVAAMRWLEERCDVLFMTGLSMGGALTVWAA 138 Query: 150 AKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEAL-YGYDYFARTCEK 208 ++P I NA + E D++ + P E G D A ++ Sbjct: 139 GQFPERFAG--IMPINAALRMESP-------DLAALAFNPDAPAELPGIGSDIKAEGVKE 189 Query: 209 W---VDGIRQFKHLPD-GNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRL 264 V + KHL G + LLPRV+CPALI+ +D +VP + + I+ + + Sbjct: 190 LAYPVTPVPAIKHLITIGAVAEMLLPRVKCPALIIQSREDHVVPPHNGELIYNGIGSTEK 249 Query: 265 HLM 267 L+ Sbjct: 250 ELL 252 >3NWO-A nrPDB Length = 330 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/245 (23%), Positives = 92/245 (37%), Gaps = 51/245 (20%) Query: 90 TVVAWDPRGYGHSR--PPDRDFPADFFERD--AKDAVDLMKALKFKKVSLLGWSDGGITA 145 TV+ +D G G+S P D PADF+ + + AL ++ +LG S GG+ Sbjct: 84 TVIHYDQVGCGNSTHLP---DAPADFWTPQLFVDEFHAVCTALGIERYHVLGQSWGGMLG 140 Query: 146 LIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDV-SKWSERTRKPLE------ALYG 198 A + PS + + I + A + + E D+ ++ TR L+ + Sbjct: 141 AEIAVRQPSGLVSLAICNSPASM----RLWSEAAGDLRAQLPAETRAALDRHEAAGTITH 196 Query: 199 YDYFARTCE--------------KWVDGIRQFK------HLPDGNICRHL---------- 228 DY E + D + Q + H +G H+ Sbjct: 197 PDYLQAAAEFYRRHVCRVVPTPQDFADSVAQMEAEPTVYHTMNGPNEFHVVGTLGDWSVI 256 Query: 229 --LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLA 286 LP V P L++ GE D P+ F+ H+ R H+ P H HL +EF + Sbjct: 257 DRLPDVTAPVLVIAGEHDEATPKTWQPFV-DHIPDVRSHVFPGTSHCTHLEKPEEFRAVV 315 Query: 287 EDFLQ 291 FL Sbjct: 316 AQFLH 320 >1A8S-A nrPDB Length = 273 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 63/267 (23%), Positives = 108/267 (40%), Gaps = 39/267 (14%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 +G Q++Y+ G G V L + + Q+ L + + V+A D RG+G S P Sbjct: 7 DGTQIYYKDWGSGQPIVFSHGWPLNADSWE--SQMIFLAAQGYRVIAHDRRGHGRSSQP- 63 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG----------ITALIAAAKYPSYI 156 + + + A D L++ L + L G+S GG TA +A A S + Sbjct: 64 --WSGNDMDTYADDLAQLIEHLDLRDAVLFGFSTGGGEVARYIGRHGTARVAKAGLISAV 121 Query: 157 HKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTR--KPLEA--LYGYDYFARTCEK---- 208 +++ A +++GIR S ++R++ K L + +G++ Sbjct: 122 PPLML-KTEANPGGLPMEVFDGIRQAS-LADRSQLYKDLASGPFFGFNQPGAKSSAGMVD 179 Query: 209 --WVDGIRQ--------FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKH 258 W+ G+ K + + L ++ P L+VHG+ D +VP A I Sbjct: 180 WFWLQGMAAGHKNAYDCIKAFSETDFTED-LKKIDVPTLVVHGDADQVVP-IEASGIASA 237 Query: 259 --VKGSRLHLMPEGKHNLHLRFADEFN 283 VKGS L + H L D+ N Sbjct: 238 ALVKGSTLKIYSGAPHGLTDTHKDQLN 264 >3LJ5-A nrPDB Length = 725 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 16/127 (12%) Query: 110 PADFFERDAKDAVDLMKALKFKKVS-------LLGWSDGGITALIAAAKYPS--YIHKMV 160 P +F+RD KD +D + F K++ + S TA++ + + +I + Sbjct: 243 PVSYFKRDIKDVIDDLADSGFIKIAERQIKRRRVYKSIITCTAVLKDKQLIAGEHIPIVP 302 Query: 161 IWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEK----WVDGIRQF 216 ++G +V ED +YEG+ ++K +R R + + + D ART +K W + I F Sbjct: 303 VFGEWGFV--EDKEVYEGVVRLTKDGQRLRNMIMS-FNADIVARTPKKKPFFWPEQIAGF 359 Query: 217 KHLPDGN 223 +H+ DGN Sbjct: 360 EHMYDGN 366 >4RNC-A nrPDB Length = 310 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 86/236 (36%), Gaps = 46/236 (19%) Query: 44 VAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSR 103 V+V+G + Y+ TG L+L +G Q+ + ++A D RG+G+S Sbjct: 28 VSVDGTSIVYRVTGNSAGTPLVLLHGWAQSSQCWGEQVLADLAADYRLIAVDLRGHGYS- 86 Query: 104 PPDRDFPADFFERDAKDAVDLMKALKFKKVS----LLGWSDGGI----------TALIAA 149 D P ++ A A D+ L + V+ LLGWS GG+ T +A Sbjct: 87 ----DAPESGYDDSANWAGDVAAVLAAEGVTENAILLGWSYGGLVICDYLAAHGTGAVAG 142 Query: 150 AKYPSYIHKM-----------VIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLE---- 194 A I + + A ED E IR + + P E Sbjct: 143 AVLVGAITSIGRGEKGGKVGSAMRSAVPGAMSEDPR--EAIRALGAFGNALTGPPEGKGA 200 Query: 195 ---ALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLV 247 AL+GY R + R H LL + P L++HG D +V Sbjct: 201 ASQALFGYSLSTRPRVRAALFNRAVGH-------DELLRNLDIPVLVLHGTDDSVV 249 >4DGQ-A nrPDB Length = 280 Score = 36.2 bits (82), Expect = 0.016, Method: Compositional matrix adjust. Identities = 63/276 (22%), Positives = 104/276 (37%), Gaps = 39/276 (14%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 +GV++ Y+ G D V+ D+ QL K F VVA D RG+G S Sbjct: 12 DGVEIFYKDWGPRDAKVIHFHHGWPLSSDDWDAQLLFFVNKGFRVVAHDRRGHGRSSQVW 71 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG--------------------ITA- 145 D + A DA +++ L +G S GG I++ Sbjct: 72 DGHDMDHY---ADDAAAVVEKLGTHGAMHVGHSTGGGEVVRYIARHGERNVSKAVLISSV 128 Query: 146 ---LIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGI--RDVSKWSERTRKPLEALYGYD 200 ++ + P+ K V A+V + Y + ++ KP E + Y+ Sbjct: 129 PPLMVKTSSNPNGTPKSVFDDFQAHVAANRAQFYLDVPAGPFYGYNRPGAKPSEGVI-YN 187 Query: 201 YFAR----TCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIH 256 ++ + + + DGI F N L + P L++HG+ D +VP + + Sbjct: 188 WWRQGMMGSTKAQYDGIVAFSQTDFTND----LKGITIPVLVIHGDDDQVVPYADSGVLS 243 Query: 257 -KHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 K VK +L H + AD+ N +FLQ Sbjct: 244 AKLVKNGKLITYKGAPHGIPTTHADKVNADLLEFLQ 279 >1HKH-A nrPDB Length = 279 Score = 35.0 bits (79), Expect = 0.036, Method: Compositional matrix adjust. Identities = 65/281 (23%), Positives = 112/281 (39%), Gaps = 55/281 (19%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 ++L+Y+ G G V+L+ G G + + Q + L + + V+ +D RG+G S + Sbjct: 13 IELYYEDQGSG-QPVVLIHGYPLDGHS-WERQTRELLAQGYRVITYDRRGFGGSSKVNTG 70 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYP-SYIHKMVIWGA-NA 166 + D F A D +++ L + V L+G+S G A+Y + K+ + Sbjct: 71 YDYDTF---AADLHTVLETLDLRDVVLVGFSMGTGELARYVARYGHERVAKLAFLASLEP 127 Query: 167 YVTDED-------SMIYEGIRDVSK-----WSERTRKPLEALYGYDYFARTCEKWVDG-- 212 ++ D +++GI +K W K L + +R E+ V G Sbjct: 128 FLVQRDDNPEGVPQEVFDGIEAAAKGDRFAWFTDFYKNFYNL-DENLGSRISEQAVTGSW 186 Query: 213 --------IRQFKHLP----DGNICRHLLPRVQCPALIVHGEKDPLVP------RFH--- 251 + + +P D + P LI+HG KD ++P RFH Sbjct: 187 NVAIGSAPVAAYAVVPAWIEDFRSDVEAVRAAGKPTLILHGTKDNILPIDATARRFHQAV 246 Query: 252 --ADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 AD++ V+G+ H L ADE N + FL Sbjct: 247 PEADYV--EVEGA--------PHGLLWTHADEVNAALKTFL 277 >4NVR-A nrPDB Length = 307 Score = 34.7 bits (78), Expect = 0.048, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 90 TVVAWDPRGYGHSRPPDRDFPA--DFFERD-AKDAVDLMKALKFKKVSLLGWSDGGITAL 146 TV+ D RGYG S P D PA + +R A+D V LM AL F + + +G GG Sbjct: 68 TVILPDLRGYGDSDKPTSD-PAHRTYSKRTMAQDIVMLMDALGFSRFAFVGHDRGGRVGH 126 Query: 147 IAAAKYPSYI 156 A YP + Sbjct: 127 RLALDYPDRV 136 >5Y6Y-B nrPDB Length = 326 Score = 34.7 bits (78), Expect = 0.054, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 21/167 (12%) Query: 44 VAVNGVQLHYQQTGEGDHAVLL--LPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 V VNG+++H + GEG + L P + S + Q+ L+ + + VA D RGYG Sbjct: 9 VEVNGIKMHVAEKGEGPVVLFLHGFPELWYS----WRHQILALSSRGYRAVAPDLRGYGD 64 Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161 + P F D + L+ L +V L+ G I +P + Sbjct: 65 TEAPVSISSYTGFHI-VGDLIALIDLLGVDQVFLVAHDWGAIIGWYLCTFHPDRV----- 118 Query: 162 WGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEK 208 AYV +++ RD + RT + A+YG DY+ +K Sbjct: 119 ---KAYVCLSVPLLH---RDPNI---RTVDAMRAMYGDDYYICRFQK 156 >3JWE-A nrPDB Length = 320 Score = 33.1 bits (74), Expect = 0.14, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 67/175 (38%), Gaps = 24/175 (13%) Query: 91 VVAWDPRGYGHSRPPDRDFPADF--FERDAKDAVDLM-KALKFKKVSLLGWSDGGITALI 147 V A D G+G S +R +DF F RD VD M K V LLG S GG A++ Sbjct: 89 VFAHDHVGHGQSEG-ERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAIL 147 Query: 148 AAAKYPSYIHKMVIWGANAYVTDEDSMIYE----------------GIRDVSKWSERTRK 191 AA+ P + MV+ E + ++ G D S S R + Sbjct: 148 TAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLS-RNKT 206 Query: 192 PLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPL 246 ++ R K GI+ + + LP++ P L++ G D L Sbjct: 207 EVDIYNSDPLICRAGLKVCFGIQLLNAV---SRVERALPKLTVPFLLLQGSADRL 258 >1A8Q-A nrPDB Length = 274 Score = 33.1 bits (74), Expect = 0.14, Method: Compositional matrix adjust. Identities = 56/230 (24%), Positives = 94/230 (40%), Gaps = 37/230 (16%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 +GV++ Y+ G+G V+ + G +G+ + QLK + + +A D RG+GHS P Sbjct: 7 DGVEIFYKDWGQG-RPVVFIHGWPLNGDA-WQDQLKAVVDAGYRGIAHDRRGHGHSTPVW 64 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG--------------------ITA- 145 + D F A D DL+ L + V+L+ S GG ++A Sbjct: 65 DGYDFDTF---ADDLNDLLTDLDLRDVTLVAHSMGGGELARYVGRHGTGRLRSAVLLSAI 121 Query: 146 ---LIAAAKYPSYIHKMVIWGANAYVTDEDSMIY----EGIRDVSKWSERTRKPLEALYG 198 +I + K P + V V E S + EG ++ + + + + Sbjct: 122 PPVMIKSDKNPDGVPDEVFDALKNGVLTERSQFWKDTAEGFFSANRPGNKVTQGNKDAFW 181 Query: 199 YDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP 248 Y A+T E V + F + L + P L+VHG+ D +VP Sbjct: 182 YMAMAQTIEGGVRCVDAFGYTD----FTEDLKKFDIPTLVVHGDDDQVVP 227 >1A88-A nrPDB Length = 275 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 55/239 (23%), Positives = 86/239 (35%), Gaps = 35/239 (14%) Query: 36 GTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWD 95 GT TS +G + Y+ G D ++ D+ Q+ + V+A D Sbjct: 1 GTVTTS-----DGTNIFYKDWGPRDGLPVVFHHGWPLSADDWDNQMLFFLSHGYRVIAHD 55 Query: 96 PRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG--ITALIAAAKYP 153 RG+G S P D + A D L +AL + +G S GG + +A A+ P Sbjct: 56 RRGHGRSDQPSTGHDMDTY---AADVAALTEALDLRGAVHIGHSTGGGEVARYVARAE-P 111 Query: 154 SYIHKMVIWGANAYV-----TDEDSMIYEGIRDVSKWSERTRK------PLEALYGYDYF 202 + K V+ A V T+ D + E + R P YG++ Sbjct: 112 GRVAKAVLVSAVPPVMVKSDTNPDGLPLEVFDEFRAALAANRAQFYIDVPSGPFYGFNRE 171 Query: 203 ARTCEK------WVDGIRQFKHLPDGNICRHL-------LPRVQCPALIVHGEKDPLVP 248 T + W+ G+ + I L R+ P L+ HG D +VP Sbjct: 172 GATVSQGLIDHWWLQGMMGAANAHYECIAAFSETDFTDDLKRIDVPVLVAHGTDDQVVP 230 >4UHD-A nrPDB Length = 282 Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust. Identities = 60/251 (23%), Positives = 98/251 (39%), Gaps = 43/251 (17%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSG----ETDFGPQLKNLNKKLFTVVAWDPRGYGHSRP 104 ++L ++ TG G LP +L G T + Q + L + F V+ D RG+G S+ Sbjct: 16 IELAFEDTGTG------LPVLLVHGFPLDRTMWKAQREELCDE-FRVIVPDLRGFGESQ- 67 Query: 105 PDRDFP-ADFFERDAKDAVDLMKALKFK-KVSLLGWSDGGITALIAAAKYPSYIHKMVIW 162 P E A D L L K+ L G S GG A A KY + +++ Sbjct: 68 ---VIPGVATMEAMADDLAGLCNHLGLTGKIVLGGLSMGGYVAFAFARKYRDRLAGLILC 124 Query: 163 GANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTC--------EKWVDGIR 214 A DS E + + +ER R+ + R C + ++ IR Sbjct: 125 DTRAR---PDS--PEAKENRRRVAERVRREGPGFIAEEMIPRLCCESTFRNHPEVIEKIR 179 Query: 215 Q--FKHLPDGNIC-----------RHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG 261 Q P+G LLP + CP L++ G+ D + P + + + + Sbjct: 180 QMILSAPPEGVAAAALGMAERPDSTDLLPALSCPTLVLVGQFDAISPPEEMEAMARTIPQ 239 Query: 262 SRLHLMPEGKH 272 S+ ++P+ H Sbjct: 240 SQFVVIPDAGH 250 >1IMJ-A nrPDB Length = 210 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%) Query: 232 VQCPALIVHGEKDPLVPRFHADFIH-KHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 V+ PALIV+G++DP+ F H K + R+ +M H +L +E++ DFL Sbjct: 150 VKTPALIVYGDQDPM---GQTSFEHLKQLPNHRVLIMKGAGHPCYLDKPEEWHTGLLDFL 206 Query: 291 Q 291 Q Sbjct: 207 Q 207 >4IQ4-A nrPDB Length = 456 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 67/280 (23%), Positives = 104/280 (37%), Gaps = 35/280 (12%) Query: 39 VTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG 98 +T + + L+Y+ G G V+L+ G SG + + Q L + V+ +D RG Sbjct: 4 ITVGQENSTSIDLYYEDHGTGT-PVVLIHGFPLSGHS-WERQSAALLDAGYRVITYDRRG 61 Query: 99 YGHSRPPDRDFPADFFER---------DAKDAVDLMKALKFKKVSLLGWSDGGITALIAA 149 +G S P + D F D +DAV + ++ +V+ S G TA IAA Sbjct: 62 FGQSSQPTTGYDYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYG--TARIAA 119 Query: 150 AKYPSYIHKMVIW---------------GANAYVTDEDSMIYEGI-RDVSKWSER--TRK 191 + + + ++ G A V + Y G D E TR Sbjct: 120 VAFLASLEPFLLKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRI 179 Query: 192 PLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP-RF 250 EA+ A + + D R +PR+ PALI+HG D +P Sbjct: 180 SEEAVRNSWNTAASGGFFAAAAAPTTWYTD---FRADIPRIDVPALILHGTGDRTLPIEN 236 Query: 251 HADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 A HK + + + H L A+E N FL Sbjct: 237 TARVFHKALPSAEYVEVEGAPHGLLWTHAEEVNTALLAFL 276 >4L7L-A nrPDB Length = 357 Score = 32.0 bits (71), Expect = 0.36, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 3/38 (7%) Query: 73 GETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFP 110 G TD G L+ L+ +TV+ P +GHS+PP + P Sbjct: 67 GPTDGGQSLEELSSHFYTVI---PHNFGHSQPPPINSP 101 >1BRO-A nrPDB Length = 277 Score = 31.6 bits (70), Expect = 0.37, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 226 RHLLPRVQCPALIVHGEKDPLVP-RFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNK 284 R +PR+ PALI+HG D +P A HK + + + H L A+E N Sbjct: 210 RADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSAEYVEVEGAPHGLLWTHAEEVNT 269 Query: 285 LAEDFL 290 FL Sbjct: 270 ALLAFL 275 >2XMZ-A nrPDB Length = 269 Score = 31.6 bits (70), Expect = 0.43, Method: Compositional matrix adjust. Identities = 51/272 (18%), Positives = 105/272 (38%), Gaps = 49/272 (18%) Query: 53 YQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPP-----DR 107 Y+ E + ++ L G L T + ++ + V+ D G+G + + Sbjct: 9 YEANVETNQVLVFLHGFLSDSRT-YHNHIEKFTDN-YHVITIDLPGHGEDQSSMDETWNF 66 Query: 108 DFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY 167 D+ +R ++ K K ++L G+S GG AL A I +++ + Sbjct: 67 DYITTLLDR-------ILDKYKDKSITLFGYSMGGRVALYYAINGHIPISNLILESTSPG 119 Query: 168 VTDEDSMIYEGIRD---------------VSKWSE------RTRKPLEALYGY--DYFAR 204 + +E + + + D V+ W + + P+E + ++ Sbjct: 120 IKEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQLELPVEIQHQIRQQRLSQ 179 Query: 205 TCEKWVDGIRQFK--HLPDGNICRHLLPR---VQCPALIVHGEKDPLVPRFHADFIHKHV 259 + K +R + +P+ L PR ++ P LI+ GE D + A + + Sbjct: 180 SPHKMAKALRDYGTGQMPN------LWPRLKEIKVPTLILAGEYDEKFVQI-AKKMANLI 232 Query: 260 KGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 S+ L+ H +H+ +DEF+ + FL+ Sbjct: 233 PNSKCKLISATGHTIHVEDSDEFDTMILGFLK 264 >1M33-A nrPDB Length = 258 Score = 30.8 bits (68), Expect = 0.64, Method: Compositional matrix adjust. Identities = 60/262 (22%), Positives = 101/262 (38%), Gaps = 48/262 (18%) Query: 53 YQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKL---FTVVAWDPRGYGHSRPPDRDF 109 +Q G+G+ ++LL G + E + ++++L FT+ D G+G SR Sbjct: 6 WQTKGQGNVHLVLLHGWGLNAEV-----WRCIDEELSSHFTLHLVDLPGFGRSRGFGALS 60 Query: 110 PADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVT 169 AD E + A D K LGWS GG+ A A +P + +V ++ + Sbjct: 61 LADMAEAVLQQAPD--------KAIWLGWSLGGLVASQIALTHPERVRALVTVASSPCFS 112 Query: 170 DEDSMIYEGIR-DV-----SKWSERTRKPLEALYGYDYF--------ARTCEKWVDGIRQ 215 D + GI+ DV + S+ ++ +E AR +K V + Sbjct: 113 ARDE--WPGIKPDVLAGFQQQLSDDQQRTVERFLALQTMGTETARQDARALKKTVLALP- 169 Query: 216 FKHLPDGNI------------CRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSR 263 +P+ ++ R L V P L ++G D LVPR + K S Sbjct: 170 ---MPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSE 226 Query: 264 LHLMPEGKHNLHLRFADEFNKL 285 ++ + H + EF L Sbjct: 227 SYIFAKAAHAPFISHPAEFCHL 248 >5XKS-A nrPDB Length = 256 Score = 30.8 bits (68), Expect = 0.73, Method: Compositional matrix adjust. Identities = 14/46 (30%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 229 LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS--RLHLMPEGKH 272 L ++ CPA++ ++D +VP +A FI+ H+ + +L +P+ H Sbjct: 181 LHKITCPAILFCSDEDHVVPPDNAPFIYDHIASADKKLVRLPDSYH 226 >3CMI-A nrPDB Length = 171 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/127 (19%), Positives = 50/127 (39%), Gaps = 12/127 (9%) Query: 77 FGPQLKNLN-------KKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALK 129 F PQ K L + FT++ + +GH P + A F + + +MK Sbjct: 46 FTPQYKELEALYKRYKDEGFTIIGFPCNQFGHQEPGSDEEIAQFCQLNYGVTFPIMK--- 102 Query: 130 FKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERT 189 K+ + G ++ + + + K + + W ++ D+ +YE ++K S + Sbjct: 103 --KIDVNGGNEDPVYKFLKSQKSGMLGLRGIKWNFEKFLVDKKGKVYERYSSLTKPSSLS 160 Query: 190 RKPLEAL 196 E L Sbjct: 161 ETIEELL 167 >3H7L-A nrPDB Length = 586 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 39/171 (22%) Query: 137 GWSD--GGITALIAAAKYPSYIHK----MVIWGANAYVTDEDSMIYEGIRDVSKWSERTR 190 GW D G ++ ++ Y +Y++ MV+W ++ + EG D++ ++ RTR Sbjct: 138 GWYDASGDVSKYLSHLSYANYLNPQQTPMVVWNILKGLS-----LLEGSEDIAAFT-RTR 191 Query: 191 KPLEALYGYDYFAR-----------TCEKWVDGIRQFKHLPDGNICRHLLPRVQC----- 234 EAL+G D+ R +KW Q + H Q Sbjct: 192 LIEEALFGADFLVRMQNEKGFFYMTVFDKWSKDTAQREICAYETQLGHKFDDYQAGFRQG 251 Query: 235 -----------PALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNL 274 L VHGE D R A+ + H+K + +G+ N+ Sbjct: 252 GGVAIAALAAASRLGVHGEYDQQKYRNAAENGYWHLKEHNTQYLNDGEENI 302 >3RLI-A nrPDB Length = 270 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 229 LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSR 263 L R+ CPALI ++D +VP +AD I + + + Sbjct: 201 LDRIVCPALIFVSDEDHVVPPGNADIIFQGISSTE 235 >1R3D-A nrPDB Length = 264 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 15/99 (15%) Query: 50 QLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF 109 QLH+ + V+L+ G+LGSG D+ P L +L + + D G+G + P+R Sbjct: 6 QLHFAKPTARTPLVVLVHGLLGSG-ADWQPVLSHLARTQCAALTLDLPGHGTN--PERH- 61 Query: 110 PADFFERDAKDAVDLMKALKFKKVS------LLGWSDGG 142 D F +AV++++ V+ L+G+S GG Sbjct: 62 -CDNF----AEAVEMIEQTVQAHVTSEVPVILVGYSLGG 95 >6NIO-A nrPDB Length = 235 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 27/74 (36%), Gaps = 11/74 (14%) Query: 178 GIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL 237 +R ER PL +YG D A K V + H P V+ P Sbjct: 153 NVRSAMALVERAEAPLGIVYGSDAVASKKVKVVGIFPEASHKP-----------VEYPMA 201 Query: 238 IVHGEKDPLVPRFH 251 IV G +P V F+ Sbjct: 202 IVKGHDNPTVTAFY 215 >1Q0R-A nrPDB Length = 298 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 14/46 (30%), Positives = 21/46 (45%) Query: 229 LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNL 274 L V P L++ E DP+ P H + + +RL +P H L Sbjct: 233 LREVTVPTLVIQAEHDPIAPAPHGKHLAGLIPTARLAEIPGMGHAL 278 >6COB-A nrPDB Length = 260 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 34/54 (62%), Gaps = 3/54 (5%) Query: 118 AKDAVDLMKAL-KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 +K ++ +K+L + ++V L+G+S GGI +AA +P+ I +V NA++ D Sbjct: 59 SKPLIETLKSLPENEEVILVGFSFGGINIALAADIFPAKIKVLVF--LNAFLPD 110 >5UNO-A nrPDB Length = 492 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 8/60 (13%) Query: 51 LHYQQTGEGDHAVLLLPGMLGSGETDFGPQL---KNLNKKL---FTVVAWDPRGYGHSRP 104 + + TG+ ++++ PG G GE+ L + L K++ F +V +DPRG SRP Sbjct: 64 IRFPATGDKIGSLVINPG--GPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRP 121 >1Y7H-A nrPDB Length = 268 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 122 VDLMKALKF-KKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA 164 ++LM++L +KV L+G S GG+ +A KYP I+ V A Sbjct: 63 MELMESLSADEKVILVGHSLGGMNLGLAMEKYPQKIYAAVFLAA 106 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2OCI-A nrPDB 329 7e-91 3V1K-A nrPDB 236 1e-62 1U2E-A nrPDB 228 1e-60 3HEA-A nrPDB 225 2e-59 4NZZ-A nrPDB 223 7e-59 2WUG-A nrPDB 205 1e-53 2XUA-A nrPDB 204 5e-53 5EGN-A nrPDB 199 1e-51 1XRN-A nrPDB 186 1e-47 3FOB-A nrPDB 186 1e-47 1A8S-A nrPDB 181 3e-46 3OM8-A nrPDB 172 2e-43 3V48-A nrPDB 168 3e-42 3BF8-A nrPDB 160 6e-40 4G5X-A nrPDB 156 8e-39 3NWO-A nrPDB 153 6e-38 3KXP-A nrPDB 138 2e-33 2JBW-A nrPDB 130 8e-31 4FBL-A nrPDB 117 5e-27 Sequences not found previously or not previously below threshold: 4DGQ-A nrPDB 144 5e-35 4IQ4-A nrPDB 142 1e-34 1A88-A nrPDB 142 2e-34 1BRO-A nrPDB 141 3e-34 1A8Q-A nrPDB 139 2e-33 1HKH-A nrPDB 134 3e-32 4UHD-A nrPDB 126 8e-30 3WMR-A nrPDB 121 4e-28 3HSS-A nrPDB 117 4e-27 4Y2Y-A nrPDB 117 6e-27 4RNC-A nrPDB 114 6e-26 5Y6Y-B nrPDB 104 3e-23 4NVR-A nrPDB 102 1e-22 4CCY-A nrPDB 101 5e-22 2XMZ-A nrPDB 98 3e-21 4CCW-A nrPDB 97 8e-21 4HTA-A nrPDB 97 9e-21 1CR6-A nrPDB 93 1e-19 1Q0R-A nrPDB 92 2e-19 5YHP-A nrPDB 92 3e-19 1M33-A nrPDB 91 7e-19 1QTR-A nrPDB 88 5e-18 4IH4-A nrPDB 87 7e-18 3RLI-A nrPDB 85 3e-17 2E3J-A nrPDB 85 4e-17 5UXZ-A nrPDB 84 6e-17 4NMW-A nrPDB 84 7e-17 1AZW-A nrPDB 83 1e-16 6AP7-A nrPDB 81 6e-16 2YYS-A nrPDB 81 6e-16 5XKS-A nrPDB 80 1e-15 3P2M-A nrPDB 78 4e-15 2EDA-A nrPDB 76 1e-14 1R1D-A nrPDB 75 3e-14 3JWE-A nrPDB 74 8e-14 3C5W-P nrPDB 73 2e-13 3FCY-A nrPDB 71 4e-13 3A2L-A nrPDB 69 3e-12 6EIC-C nrPDB 68 5e-12 5HK8-A nrPDB 67 8e-12 4GDM-A nrPDB 66 1e-11 1R3D-A nrPDB 65 3e-11 1IMJ-A nrPDB 64 8e-11 2O2H-A nrPDB 61 6e-10 6COB-A nrPDB 60 9e-10 2WFL-A nrPDB 57 7e-09 3FLA-A nrPDB 57 1e-08 3IBT-A nrPDB 56 2e-08 4ZWN-A nrPDB 55 3e-08 3DYV-A nrPDB 55 4e-08 2RON-A nrPDB 55 4e-08 1SCK-A nrPDB 53 1e-07 2PSJ-A nrPDB 53 2e-07 2Y6V-A nrPDB 52 3e-07 2WJ4-A nrPDB 52 4e-07 6FKX-A nrPDB 51 4e-07 3KSR-A nrPDB 51 6e-07 1Y7H-A nrPDB 50 1e-06 5L8S-A nrPDB 49 2e-06 3O4I-A nrPDB 49 3e-06 6FVJ-A nrPDB 47 7e-06 1DWO-A nrPDB 47 1e-05 1OIL-A nrPDB 46 2e-05 2HCU-A nrPDB 44 7e-05 1TAH-B nrPDB 44 8e-05 4GW3-A nrPDB 43 1e-04 3I2H-A nrPDB 43 1e-04 4HXF-B nrPDB 43 2e-04 5D6O-A nrPDB 43 2e-04 3VVL-A nrPDB 43 2e-04 5T88-A nrPDB 43 2e-04 3WYD-A nrPDB 42 2e-04 5J7Z-A nrPDB 42 2e-04 2VAV-A nrPDB 42 2e-04 3I1I-A nrPDB 42 2e-04 5UNO-A nrPDB 42 2e-04 4QLO-A nrPDB 42 3e-04 4Q1V-A nrPDB 42 4e-04 5EFZ-A nrPDB 41 5e-04 6HIX-BG nrPDB 41 5e-04 3N0T-A nrPDB 41 7e-04 5XB6-A nrPDB 41 0.001 5OLJ-A nrPDB 40 0.001 5UGZ-A nrPDB 40 0.001 1UFO-A nrPDB 40 0.001 6EOT-A nrPDB 40 0.001 1DIN-A nrPDB 39 0.002 3I6Y-A nrPDB 39 0.002 2XLB-A nrPDB 39 0.002 2EEP-A nrPDB 39 0.002 5AOA-A nrPDB 38 0.004 2PL5-A nrPDB 38 0.005 2HDW-A nrPDB 38 0.005 2ECF-A nrPDB 38 0.006 6EOR-A nrPDB 38 0.006 3AZQ-A nrPDB 38 0.006 3FNB-A nrPDB 38 0.006 3FCX-A nrPDB 37 0.006 3QMW-A nrPDB 37 0.007 6IGR-A nrPDB 37 0.007 6BFZ-A nrPDB 37 0.008 4XCH-A nrPDB 37 0.009 5V41-A nrPDB 37 0.011 3E4D-A nrPDB 37 0.011 3VT2-A nrPDB 37 0.012 4NRS-A nrPDB 37 0.012 3N2Z-B nrPDB 37 0.013 3D2A-A nrPDB 36 0.014 6BA9-A nrPDB 36 0.016 2PPL-A nrPDB 36 0.018 5W8P-A nrPDB 36 0.019 3PLN-A nrPDB 36 0.020 3TEJ-A nrPDB 36 0.022 1HLG-A nrPDB 36 0.022 4IXL-A nrPDB 36 0.029 3LA8-A nrPDB 35 0.032 5CHZ-A nrPDB 35 0.033 3H2H-A nrPDB 35 0.037 4X97-A nrPDB 35 0.041 1LPA-B nrPDB 35 0.041 1THT-A nrPDB 35 0.042 5YAL-A nrPDB 35 0.049 5JKJ-A nrPDB 35 0.051 3L86-A nrPDB 34 0.056 3U31-A nrPDB 34 0.057 3L7V-A nrPDB 34 0.059 5T6O-A nrPDB 34 0.064 4F1R-A nrPDB 34 0.064 5YP1-A nrPDB 34 0.066 4FS9-A nrPDB 34 0.073 4EB0-A nrPDB 34 0.076 4M02-A nrPDB 34 0.086 4E1Q-A nrPDB 34 0.096 1AUO-A nrPDB 34 0.11 5X6S-A nrPDB 33 0.13 5Z9R-A nrPDB 33 0.14 3GZ3-A nrPDB 33 0.14 5W8O-A nrPDB 33 0.15 2QS9-A nrPDB 33 0.15 2B61-A nrPDB 33 0.15 4IRN-A nrPDB 33 0.15 4B6G-A nrPDB 33 0.16 1DT3-A nrPDB 33 0.16 6QPR-A nrPDB 33 0.17 4NPN-A nrPDB 33 0.17 2RDU-A nrPDB 33 0.17 4TGL-A nrPDB 33 0.19 1ODT-C nrPDB 33 0.19 3K3P-A nrPDB 33 0.20 1JFR-A nrPDB 32 0.21 5CTQ-A nrPDB 32 0.23 4HBK-A nrPDB 32 0.23 5ZBB-B nrPDB 32 0.24 5DWD-A nrPDB 32 0.24 4Y12-A nrPDB 32 0.24 5LOW-E nrPDB 32 0.25 5LOB-E nrPDB 32 0.25 5JYK-A nrPDB 32 0.26 5ILA-A nrPDB 32 0.26 2B20-A nrPDB 32 0.27 3RPL-B nrPDB 32 0.30 3L87-A nrPDB 32 0.30 4N8K-A nrPDB 32 0.32 4ZCK-A nrPDB 32 0.32 1GPL-A nrPDB 32 0.33 5XCN-X nrPDB 32 0.33 3RK6-A nrPDB 32 0.33 4QPJ-A nrPDB 32 0.33 6AVW-A nrPDB 32 0.35 5K52-A nrPDB 32 0.35 5A2B-A nrPDB 32 0.35 4X9L-A nrPDB 32 0.35 1RP1-A nrPDB 32 0.35 5K53-A nrPDB 32 0.36 4WZH-A nrPDB 32 0.38 3ENV-A nrPDB 32 0.38 3L8A-A nrPDB 32 0.39 2QJ0-A nrPDB 32 0.39 3L9C-A nrPDB 32 0.41 3PSP-A nrPDB 32 0.43 3LEH-A nrPDB 32 0.43 3CNC-A nrPDB 32 0.44 1BU8-A nrPDB 31 0.45 4WTS-A nrPDB 31 0.47 4HG5-A nrPDB 31 0.47 6CHV-A nrPDB 31 0.47 3W9B-A nrPDB 31 0.47 3CN7-A nrPDB 31 0.47 6ERD-A nrPDB 31 0.49 3LNB-A nrPDB 31 0.51 4GAX-A nrPDB 31 0.52 3LBE-A nrPDB 31 0.52 4JEK-A nrPDB 31 0.54 6CF1-A nrPDB 31 0.54 3WNW-A nrPDB 31 0.55 5LOW-D nrPDB 31 0.58 5HXY-A nrPDB 31 0.60 2UXN-B nrPDB 31 0.60 2BMB-A nrPDB 31 0.61 6O09-C nrPDB 31 0.63 6GII-A nrPDB 31 0.64 4MQM-A nrPDB 31 0.64 2YH2-A nrPDB 31 0.64 2NT8-A nrPDB 31 0.65 6BJE-A nrPDB 31 0.66 5C2O-A nrPDB 31 0.68 3L8R-A nrPDB 31 0.70 3ZF4-A nrPDB 31 0.71 5U50-A nrPDB 31 0.71 3OXG-A nrPDB 31 0.72 5I5F-A nrPDB 31 0.73 6MSO-A nrPDB 31 0.73 6MSN-A nrPDB 31 0.73 5GV1-A nrPDB 31 0.73 3WG8-A nrPDB 31 0.73 3NC3-A nrPDB 31 0.73 3L7R-A nrPDB 31 0.73 5L6F-A nrPDB 31 0.74 3SR7-A nrPDB 31 0.76 6QGB-A nrPDB 31 0.78 5Z6H-A nrPDB 31 0.78 5BV7-A nrPDB 31 0.80 4XBS-A nrPDB 31 0.82 1FJ2-A nrPDB 31 0.82 3QAU-A nrPDB 31 0.83 2QM9-A nrPDB 31 0.86 4J0Q-A nrPDB 31 0.86 2PVS-A nrPDB 31 0.88 6MLK-A nrPDB 31 0.89 1ETH-A nrPDB 31 0.91 5GVX-A nrPDB 31 0.92 4H27-A nrPDB 31 0.95 5D3Z-A nrPDB 31 0.97 4M03-A nrPDB 31 0.98 5J32-A nrPDB 31 0.99 6ECE-A nrPDB 30 1.00 5XTZ-A nrPDB 30 1.0 5XTP-A nrPDB 30 1.0 5JZV-A nrPDB 30 1.0 5JRE-A nrPDB 30 1.0 5C1S-A nrPDB 30 1.0 4M46-A nrPDB 30 1.0 4M00-A nrPDB 30 1.0 4IG7-A nrPDB 30 1.0 4ETM-A nrPDB 30 1.0 4ABN-A nrPDB 30 1.0 3VTW-A nrPDB 30 1.0 3OIX-A nrPDB 30 1.0 3L9D-A nrPDB 30 1.0 3CZC-A nrPDB 30 1.0 4EGS-A nrPDB 30 1.1 2DGA-A nrPDB 30 1.1 3DEZ-A nrPDB 30 1.1 6GI5-A nrPDB 30 1.2 3H76-A nrPDB 30 1.2 2LEC-A nrPDB 30 1.2 4OTK-A nrPDB 30 1.2 4U5I-A nrPDB 30 1.3 2QUB-A nrPDB 30 1.3 4ETN-A nrPDB 30 1.3 4KML-A nrPDB 30 1.3 5KRE-A nrPDB 30 1.4 3NIB-A nrPDB 30 1.4 6G21-A nrPDB 30 1.4 2BDW-A nrPDB 30 1.4 4QPJ-C nrPDB 30 1.4 3QLL-A nrPDB 30 1.4 1KNW-A nrPDB 30 1.5 4R1D-A nrPDB 30 1.6 5LZ5-A nrPDB 30 1.6 3UL6-A nrPDB 30 1.6 5EX6-C nrPDB 30 1.7 3GA7-A nrPDB 30 1.7 5JZX-A nrPDB 29 1.7 3BGK-A nrPDB 29 1.7 3MGC-A nrPDB 29 1.7 3TKA-A nrPDB 29 1.8 4L7V-A nrPDB 29 1.8 2BHS-A nrPDB 29 1.8 5AUQ-A nrPDB 29 2.0 3UDT-A nrPDB 29 2.0 3W53-A nrPDB 29 2.1 4QNN-A nrPDB 29 2.3 3F4L-A nrPDB 29 2.4 3Q9V-A nrPDB 29 2.5 1HPL-A nrPDB 29 2.7 6OAZ-A nrPDB 29 2.8 5LOB-A nrPDB 29 2.9 4XWN-A nrPDB 29 3.3 3Q6B-A nrPDB 29 3.3 5AH0-A nrPDB 29 3.5 2QT9-A nrPDB 28 3.8 4AMY-A nrPDB 28 3.9 1V02-A nrPDB 28 3.9 4MSX-A nrPDB 28 4.7 4Q3K-A nrPDB 28 5.0 6AQO-A nrPDB 28 5.5 3LS2-A nrPDB 28 5.5 4LIV-A nrPDB 28 5.7 2X4L-A nrPDB 28 6.1 5LW6-A nrPDB 28 6.2 5GW8-A nrPDB 28 6.3 3MGA-A nrPDB 27 6.5 4BZW-A nrPDB 27 6.6 1R88-A nrPDB 27 6.8 2HFJ-A nrPDB 27 7.8 6AGQ-A nrPDB 27 8.4 6CL4-A nrPDB 27 9.2 >2OCI-A nrPDB Length = 254 Score = 329 bits (844), Expect = 7e-91, Method: Composition-based stats. Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 38 SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPR 97 SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPR Sbjct: 1 SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPR 60 Query: 98 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH 157 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH Sbjct: 61 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH 120 Query: 158 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 217 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK Sbjct: 121 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 180 Query: 218 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLR 277 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLR Sbjct: 181 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLR 240 Query: 278 FADEFNKLAEDFLQ 291 FADEFNKLAEDFLQ Sbjct: 241 FADEFNKLAEDFLQ 254 >3V1K-A nrPDB Length = 286 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 75/285 (26%), Positives = 113/285 (39%), Gaps = 28/285 (9%) Query: 33 AAFGTSVTSAKVAVN-----GVQLHYQQTGEGDHAVLLLPGMLGSGET-DFGPQLKNLNK 86 A S TS V +N +HY + G G+ ++L G G+G ++ + Sbjct: 2 TALTESSTSKFVKINEKGFSDFNIHYNEAGNGETVIMLHGGGPGAGGWSNYYRNVGPFVD 61 Query: 87 KLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITAL 146 + V+ D G+ S D A+ LM AL + L+G S GG TAL Sbjct: 62 AGYRVILKDSPGFNKSDAVVMDEQRGLVN--ARAVKGLMDALDIDRAHLVGNSMGGATAL 119 Query: 147 IAAAKYPSYIHKMVIWGANAYVTDED-SMIYEGIRDVSKW----SERTRKPLEALYGYDY 201 A +YP I K+++ G M EGI+ + K S T K + ++ YD Sbjct: 120 NFALEYPDRIGKLILMGPGGLGPSMFAPMPMEGIKLLFKLYAEPSYETLKQMLQVFLYDQ 179 Query: 202 FARTCE----KWVDGIRQFKHLPDGNICRHLLP-----------RVQCPALIVHGEKDPL 246 T E +W RQ +HL + I P ++ I G D Sbjct: 180 SLITEELLQGRWEAIQRQPEHLKNFLISAQKAPLSTWDVTARLGEIKAKTFITWGRDDRF 239 Query: 247 VPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 VP H + ++ +RLH+ + ADEFN+L DFL+ Sbjct: 240 VPLDHGLKLLWNIDDARLHVFSKCGQWAQWEHADEFNRLVIDFLR 284 >1U2E-A nrPDB Length = 289 Score = 228 bits (582), Expect = 1e-60, Method: Composition-based stats. Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 32/283 (11%) Query: 36 GTSVTSAKVAVNG----VQLHYQQTGEGDHAVLLLPG--MLGSGETDFGPQLKNLNKKLF 89 + TS + V +++H+ G+GD V+LL G +G +F + L + + Sbjct: 8 TEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGY 67 Query: 90 TVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAA 149 V+ D G+G S A+ ++ L K+ LLG S GG +++ Sbjct: 68 RVILLDCPGWGKSDSVVNSGSRSDLN--ARILKSVVDQLDIAKIHLLGNSMGGHSSVAFT 125 Query: 150 AKYPSYIHKMVIWGA-NAYVTDEDSMIYEGIRDVSK-WSERTRKPLEALYGYDYFARTCE 207 K+P + K+V+ G ++ M EGI+ +++ + + T + L+ + D F Sbjct: 126 LKWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMM--DIFVFDTS 183 Query: 208 KWVDGIRQFK--------------------HLPDGNICRHLLPRVQCPALIVHGEKDPLV 247 D + + + + L ++ LIV G D V Sbjct: 184 DLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFV 243 Query: 248 PRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 P + + GS LH+ + H AD FN+L +FL Sbjct: 244 PMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFL 286 >3HEA-A nrPDB Length = 271 Score = 225 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 55/275 (20%), Positives = 115/275 (41%), Gaps = 29/275 (10%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 S VA +G Q++++ G G + L + ++ Q++ L+ + + +A+D RG+G Sbjct: 1 STFVAKDGTQIYFKDWGSGKPVLFSHGWPLDADMWEY--QMEYLSSRGYRTIAFDRRGFG 58 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPS-YIHKM 159 S P + + ++ A D L++ L K+V+L+G+S GG A++ S + + Sbjct: 59 RSDQP---WTGNDYDTFADDIAQLIEHLDLKEVTLVGFSMGGGDVARYIARHGSARVAGL 115 Query: 160 VIWGANAYVTDEDSMIYEGI-------------RDVSKWSERTRKPLEALYGYDYFARTC 206 V+ GA + + +G+ +D +++ P + ++ Sbjct: 116 VLLGAVTPIFGQKPDYPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINKGQVVSQGV 175 Query: 207 EKWVDGIRQFKHLPDGNIC---------RHLLPRVQCPALIVHGEKDPLVP-RFHADFIH 256 + I L C R + ++ P L++HG+ D +VP Sbjct: 176 QTQTLQIALLASLKATVDCVTAFAETDFRPDMAKIDVPTLVIHGDGDQIVPFETTGKVAA 235 Query: 257 KHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + +KG+ L + + H + A + N+ FL+ Sbjct: 236 ELIKGAELKVYKDAPHGFAVTHAQQLNEDLLAFLK 270 >4NZZ-A nrPDB Length = 320 Score = 223 bits (568), Expect = 7e-59, Method: Composition-based stats. Identities = 62/308 (20%), Positives = 105/308 (34%), Gaps = 45/308 (14%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G ++ + VNGV LHY G+G+ + L S + Q+ Sbjct: 18 GSHMASMTGGQQMGRGMSKQYINVNGVNLHYISKGQGELMLFLHGFPDFS--HIWRHQID 75 Query: 83 NLNKKLFTVVAWDPRGYGHSRPPD--RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSD 140 + F VA D RGY S P + D D +++ L + +L+ Sbjct: 76 EFSND-FHTVALDLRGYNLSEKPSGLESYEIDVLVE---DIRQVIEGLGYSSCTLVVHDW 131 Query: 141 GGITALIAAAKYPSYIHKMVIW-GANAYVTDEDS------------MIYEGIRDVSKWSE 187 G A +YP Y+ K++ + G + Y + M + ++V + E Sbjct: 132 GAGIGWTFAYRYPEYVQKLIAFNGPHPYTFMRELRTNKNQQKASEYMKWFQKQEVQDYME 191 Query: 188 RTR-----------KPLEALYGYDYFARTCEKWVDG--------IRQFKHLPDGNICRHL 228 R + D W +G R K + ++ R Sbjct: 192 RDNFSGLRKLVIDPGVKKGYLTADDVQAYMNSWENGSVLSMLSYYRNLKIFTEEDLRRKS 251 Query: 229 L-----PRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFN 283 L + P I+ G +DP + D I ++V +H + E H E N Sbjct: 252 LFPLEEEVLNIPVQIIWGNQDPTFMPENLDGIEEYVPNISVHRLAEASHAPQHEKPQEVN 311 Query: 284 KLAEDFLQ 291 + +FL Sbjct: 312 NVMWNFLN 319 >2WUG-A nrPDB Length = 291 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 83/292 (28%), Positives = 130/292 (44%), Gaps = 35/292 (11%) Query: 28 RAGPAAAFGTSVTSAKVAVNG-VQLHYQQTGEG-DHAVLLLPG--MLGSGETDFGPQLKN 83 A F ++ A+V V+G ++LHY + G G D V+LL G + T+F + Sbjct: 2 TATEELTFESTSRFAEVDVDGPLKLHYHEAGVGNDQTVVLLHGGGPGAASWTNFSRNIAV 61 Query: 84 LNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAV-DLMKALKFKKVSLLGWSDGG 142 L + F V+A D GYGHS F R A A+ L L +V L+G + GG Sbjct: 62 LARH-FHVLAVDQPGYGHSDK---RAEHGQFNRYAAMALKGLFDQLGLGRVPLVGNALGG 117 Query: 143 ITALIAAAKYPSYIHKMVIWGANA-YVTDEDSMIYEGIRDVSKWS-ERTRKPLEA---LY 197 TA+ A YP+ ++V+ G + EG++ +SK+S TR+ LEA + Sbjct: 118 GTAVRFALDYPARAGRLVLMGPGGLSINLFAPDPTEGVKRLSKFSVAPTRENLEAFLRVM 177 Query: 198 GYDYFARTCEKWVDGIRQFKHLPD-------------------GNICRHLLPRVQCPALI 238 YD T + VD P+ G + R + R++ P L+ Sbjct: 178 VYDKNLIT-PELVDQRFALASTPESLTATRAMGKSFAGADFEAGMMWREVY-RLRQPVLL 235 Query: 239 VHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 + G +D + P A K + ++LH+ + H + + DEFNKL +FL Sbjct: 236 IWGREDRVNPLDGALVALKTIPRAQLHVFGQCGHWVQVEKFDEFNKLTIEFL 287 >2XUA-A nrPDB Length = 266 Score = 204 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 65/270 (24%), Positives = 114/270 (42%), Gaps = 25/270 (9%) Query: 38 SVTSAKVAVNGVQLHYQQTGE--GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWD 95 AVNG +LHY+ GE G+ ++L LG+ + + PQ+ L+K F V+ +D Sbjct: 1 GSHMPYAAVNGTELHYRIDGERHGNAPWIVLSNSLGTDLSMWAPQVAALSKH-FRVLRYD 59 Query: 96 PRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSY 155 RG+GHS P + E+ D + LM LK + + G S GG+T + AA++ Sbjct: 60 TRGHGHSEAPKGPYT---IEQLTGDVLGLMDTLKIARANFCGLSMGGLTGVALAARHADR 116 Query: 156 IHKMVIWGANAYVTDEDSMIYEGIRDVSK---------------WSERTRKPLEALYGYD 200 I ++ + A + + + ++ ++ R+P+ D Sbjct: 117 IERVALCNTAARIGSPEVWVPRAVKARTEGMHALADAVLPRWFTADYMEREPVVLAMIRD 176 Query: 201 YFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVK 260 F T + +G D R P ++ PAL++ G D + + + Sbjct: 177 VFVHTDK---EGYASNCEAIDAADLRPEAPGIKVPALVISGTHDLAATPAQGRELAQAIA 233 Query: 261 GSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 G+R ++ + H ++ AD F K DFL Sbjct: 234 GAR-YVELDASHISNIERADAFTKTVVDFL 262 >5EGN-A nrPDB Length = 271 Score = 199 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 62/264 (23%), Positives = 105/264 (39%), Gaps = 24/264 (9%) Query: 44 VAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSR 103 V +GV+++Y GEG V L P G F Q + V+ D RG+G S Sbjct: 4 VENDGVKIYYDSYGEGVPIVFLHPFSTNGGIWYF--QTFPFAQTN-HVIVIDHRGHGRSD 60 Query: 104 PPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWG 163 P + A D V ++ ALK + +G S GG+ A+ +P + +I Sbjct: 61 KPATGYS---IMEHADDVVAVLDALKVDRAVFVGNSIGGMIAMQLNLDHPQRVIGNLILS 117 Query: 164 ------------ANAYVTDEDSMIYEGI--RDVSKWSERTRKPLEALYGYDYFARTCEKW 209 A A ++ + G+ VS S+R R + A+ +F+ Sbjct: 118 SGTGLGEGMPPEAGAAFQNDYIGAFGGLLEGAVSARSKRERPEILAVMKA-HFSVPSNFP 176 Query: 210 VDGIRQFKHLPDGNICRHL---LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHL 266 P+G ++ L +Q P L+V GE+D + + + ++ G+ L + Sbjct: 177 KHVFDAATADPNGVFAWNIKDRLSSIQAPTLVVAGEEDLVTTVANNQLLADNIPGAELRV 236 Query: 267 MPEGKHNLHLRFADEFNKLAEDFL 290 + + H L EFN+L F+ Sbjct: 237 INDVGHFYQLERPSEFNELLRGFV 260 >1XRN-A nrPDB Length = 293 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 69/285 (24%), Positives = 117/285 (41%), Gaps = 41/285 (14%) Query: 43 KVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGET-DFGPQLKNLNKKLFTVVAWDPRGYGH 101 VNG+ ++Y+ + L+ G G + D+ L+++ K+ TV+ +D G G Sbjct: 9 YAKVNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQFGCGR 68 Query: 102 SRPPDRD-FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV 160 S PD+ F D+ +A+ + +KV L+G S GG AL A KY ++ ++ Sbjct: 69 SEEPDQSKFTIDYGVEEAEALRSKL--FGNEKVFLMGSSYGGALALAYAVKYQDHLKGLI 126 Query: 161 IWGA----NAYVTDEDSMIYE---------------GIRDVSKWSERTRK---------- 191 + G V + + +I E G + ++ E Sbjct: 127 VSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEYQEAVNYFYHQHLLRSE 186 Query: 192 --PLEALYGYDYFAR-TCEKWVDGIRQFKHL---PDGNICRHLLPRVQCPALIVHGEKDP 245 P E L +Y R + ++G QF D +I + ++ P LI GE D Sbjct: 187 DWPPEVLKSLEYAERRNVYRIMNGPNQFTITGTIKDWDIT-DKISAIKIPTLITVGEYDE 245 Query: 246 LVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 + P A IH+ + GS LH+ + H + +NKL DF+ Sbjct: 246 VTPNV-ARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFI 289 >3FOB-A nrPDB Length = 281 Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 65/273 (23%), Positives = 113/273 (41%), Gaps = 39/273 (14%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 ++++Y+ G G VL+ L ++ Q+ L + + V+ +D RG+G S P Sbjct: 17 IEIYYEDHGTGKPVVLIHGWPLSGRSWEY--QVPALVEAGYRVITYDRRGFGKSSQPWEG 74 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITA--------------LIAAAKYPS 154 + D F D L++ L+ + V+L+G+S GG ++ A P Sbjct: 75 YEYDTF---TSDLHQLLEQLELQNVTLVGFSMGGGEVARYISTYGTDRIEKVVFAGAVPP 131 Query: 155 YIHK------------MVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEA--LYGYD 200 Y++K + + + D + + E + +RT E+ LY +D Sbjct: 132 YLYKSEDHPEGALDDATIETFKSGVINDRLAFLDEFTKGFFAAGDRTDLVSESFRLYNWD 191 Query: 201 YFARTCEK-WVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP-RFHADFIHKH 258 A K +D I F R L + P LI+HG+ D VP + H+ Sbjct: 192 IAAGASPKGTLDCITAFSKT----DFRKDLEKFNIPTLIIHGDSDATVPFEYSGKLTHEA 247 Query: 259 VKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + S++ L+ G H L+ A EFN+ FL+ Sbjct: 248 IPNSKVALIKGGPHGLNATHAKEFNEALLLFLK 280 >1A8S-A nrPDB Length = 273 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 56/279 (20%), Positives = 100/279 (35%), Gaps = 35/279 (12%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 + +G Q++Y+ G G V L + + Q+ L + + V+A D RG+G Sbjct: 1 TTFTTRDGTQIYYKDWGSGQPIVFSHGWPLNADS--WESQMIFLAAQGYRVIAHDRRGHG 58 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKY-------- 152 S P + + + A D L++ L + L G+S GG ++ Sbjct: 59 RSSQP---WSGNDMDTYADDLAQLIEHLDLRDAVLFGFSTGGGEVARYIGRHGTARVAKA 115 Query: 153 --PSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEA---LYGYDYFARTCE 207 S + +++ A +++GIR S A +G++ Sbjct: 116 GLISAVPPLML-KTEANPGGLPMEVFDGIRQASLADRSQLYKDLASGPFFGFNQPGAKSS 174 Query: 208 K------WVDGIRQ--------FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP-RFHA 252 W+ G+ K + + L ++ P L+VHG+ D +VP Sbjct: 175 AGMVDWFWLQGMAAGHKNAYDCIKAFSETDFTED-LKKIDVPTLVVHGDADQVVPIEASG 233 Query: 253 DFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 VKGS L + H L D+ N F++ Sbjct: 234 IASAALVKGSTLKIYSGAPHGLTDTHKDQLNADLLAFIK 272 >3OM8-A nrPDB Length = 266 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 63/269 (23%), Positives = 107/269 (39%), Gaps = 42/269 (15%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 +G L Y+ G + +L L +G+ + QL L + F V+ +D RG+G S P Sbjct: 13 DGASLAYRLDGAAEKPLLALSNSIGTTLHMWDAQLPALTRH-FRVLRYDARGHGASSVPP 71 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANA 166 + R +D ++L+ AL+ ++ LG S GGI A P I ++V+ +A Sbjct: 72 GPYT---LARLGEDVLELLDALEVRRAHFLGLSLGGIVGQWLALHAPQRIERLVLANTSA 128 Query: 167 YVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKW------------VDGIR 214 + + ++W ER L+A + A W V+ R Sbjct: 129 W-----------LGPAAQWDERIAAVLQAEDMSETAAGFLGNWFPPALLERAEPVVERFR 177 Query: 215 Q-------------FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG 261 F + D ++ R L R++ P L++ G D + H + I + G Sbjct: 178 AMLMATNRHGLAGSFAAVRDTDL-RAQLARIERPTLVIAGAYDTVTAASHGELIAASIAG 236 Query: 262 SRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 +RL +P H ++ F F FL Sbjct: 237 ARLVTLP-AVHLSNVEFPQAFEGAVLSFL 264 >3V48-A nrPDB Length = 268 Score = 168 bits (424), Expect = 3e-42, Method: Composition-based stats. Identities = 52/242 (21%), Positives = 102/242 (42%), Gaps = 24/242 (9%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKD 120 V+L+ G+ GSG + + PQL L ++ + VV +D RG G++ PD + A + Sbjct: 16 PVVVLISGLGGSG-SYWLPQLAVLEQE-YQVVCYDQRGTGNN--PDTLAEDYSIAQMAAE 71 Query: 121 AVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIR 180 + A + +++G + G + + A YP+ + ++ + ++ +R Sbjct: 72 LHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQ-VR 130 Query: 181 DVSKWSERTRKPLEA----LYGYDYFARTCEKWV--------------DGIRQFKHLPDG 222 + +S + +EA LY D+ A + + +R+ L Sbjct: 131 ERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRA 190 Query: 223 NICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEF 282 + H R++CP I+ D LVP + +H + S+ +MP G H ++ + F Sbjct: 191 DFSHH-ADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETF 249 Query: 283 NK 284 N Sbjct: 250 NA 251 >3BF8-A nrPDB Length = 255 Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats. Identities = 58/247 (23%), Positives = 100/247 (40%), Gaps = 22/247 (8%) Query: 59 GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHS-RPPDRDFPADFFERD 117 + ++L+ G+ GS + G ++L ++ D R +G S R P ++PA Sbjct: 15 NNSPIVLVHGLFGS-LDNLGVLARDLVND-HNIIQVDVRNHGLSPREPVMNYPAM----- 67 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV---IWGANAYVTDEDSM 174 A+D VD + A + K + +G S GG + A P I K+V I + +V D Sbjct: 68 AQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALAPDRIDKLVAIDIAPVDYHVRRHDE- 126 Query: 175 IYEGIRDVSKWSERTRKPLEALYGYD-----YFARTCEKWVDGIRQFKHLPDGNICRHL- 228 I+ I VS+ +TR+ A+ + +VDG +F + H+ Sbjct: 127 IFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQFLLKSFVDGEWRFNVPVLWDQYPHIV 186 Query: 229 ----LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNK 284 +P PAL + G P V + D + +R H++ H +H D + Sbjct: 187 GWEKIPAWDHPALFIPGGNSPYVSEQYRDDLLAQFPQARAHVIAGAGHWVHAEKPDAVLR 246 Query: 285 LAEDFLQ 291 +L Sbjct: 247 AIRRYLN 253 >4G5X-A nrPDB Length = 279 Score = 156 bits (395), Expect = 8e-39, Method: Composition-based stats. Identities = 62/255 (24%), Positives = 102/255 (40%), Gaps = 29/255 (11%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSR---PPDRDFPADFF 114 EG+ A LL+ S F PQL+ K + V+A D G+G S PDR + + + Sbjct: 21 EGEGAPLLMIHGNSSSGAIFAPQLEGEIGKKWRVIAPDLPGHGKSTDAIDPDRSYSMEGY 80 Query: 115 ERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSM 174 A ++M+ L + GWS GG + A+YP + ++I G +E Sbjct: 81 ---ADAMTEVMQQLGIADAVVFGWSLGGHIGIEMIARYPE-MRGLMITGTPPVAREEVGQ 136 Query: 175 IYE-------------GIRDVSKWSERT-RKPLEALYGYDYFARTCEKWVDGIRQFKHLP 220 ++ RDV ++ T +P EA D ART + + + Sbjct: 137 GFKSGPDMALAGQEIFSERDVESYARSTCGEPFEASL-LDIVARTDGRARRIMFEKFGSG 195 Query: 221 DGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS----RLHLMPEGKHNLHL 276 G R ++ Q P +V+G +P V DF+ K G+ + H++ H Sbjct: 196 TGGNQRDIVAEAQLPIAVVNGRDEPFV---ELDFVSKVKFGNLWEGKTHVIDNAGHAPFR 252 Query: 277 RFADEFNKLAEDFLQ 291 EF+ F++ Sbjct: 253 EAPAEFDAYLARFIR 267 >3NWO-A nrPDB Length = 330 Score = 153 bits (387), Expect = 6e-38, Method: Composition-based stats. Identities = 60/273 (21%), Positives = 102/273 (37%), Gaps = 50/273 (18%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKK-LFTVVAWDPRGYGHSRPPDRDFPADFFER--D 117 ++L G + ++ + L + TV+ +D G G+S D PADF+ Sbjct: 56 PLIVLHGGPGMA--HNYVANIAALADETGRTVIHYDQVGCGNSTHLP-DAPADFWTPQLF 112 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE 177 + + AL ++ +LG S GG+ A + PS + + I + A + + E Sbjct: 113 VDEFHAVCTALGIERYHVLGQSWGGMLGAEIAVRQPSGLVSLAICNSPASMR----LWSE 168 Query: 178 GIRDV-SKWSERTRKPLE------ALYGYDYFAR--------------TCEKWVDGIRQF 216 D+ ++ TR L+ + DY T + + D + Q Sbjct: 169 AAGDLRAQLPAETRAALDRHEAAGTITHPDYLQAAAEFYRRHVCRVVPTPQDFADSVAQM 228 Query: 217 K------HLPDGNICRHL------------LPRVQCPALIVHGEKDPLVPRFHADFIHKH 258 + H +G H+ LP V P L++ GE D P+ F+ H Sbjct: 229 EAEPTVYHTMNGPNEFHVVGTLGDWSVIDRLPDVTAPVLVIAGEHDEATPKTWQPFV-DH 287 Query: 259 VKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + R H+ P H HL +EF + FL Sbjct: 288 IPDVRSHVFPGTSHCTHLEKPEEFRAVVAQFLH 320 >4DGQ-A nrPDB Length = 280 Score = 144 bits (362), Expect = 5e-35, Method: Composition-based stats. Identities = 55/283 (19%), Positives = 90/283 (31%), Gaps = 31/283 (10%) Query: 36 GTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWD 95 G +GV++ Y+ G D V+ D+ QL K F VVA D Sbjct: 1 GPGSMGTVTTKDGVEIFYKDWGPRDAKVIHFHHGWPLSSDDWDAQLLFFVNKGFRVVAHD 60 Query: 96 PRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSY 155 RG+G S + A DA +++ L +G S GG + A++ Sbjct: 61 RRGHGRSSQVWDGH---DMDHYADDAAAVVEKLGTHGAMHVGHSTGGGEVVRYIARHGER 117 Query: 156 -IHKMVIWGANAYVTDEDSMIYEGI-------------------------RDVSKWSERT 189 + K V+ + + + S G ++ Sbjct: 118 NVSKAVLISSVPPLMVKTSSNPNGTPKSVFDDFQAHVAANRAQFYLDVPAGPFYGYNRPG 177 Query: 190 RKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP- 248 KP E + + + + L + P L++HG+ D +VP Sbjct: 178 AKPSEGVIYNWWRQGMMGSTKAQYDGIVAFSQTDFT-NDLKGITIPVLVIHGDDDQVVPY 236 Query: 249 RFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 K VK +L H + AD+ N +FLQ Sbjct: 237 ADSGVLSAKLVKNGKLITYKGAPHGIPTTHADKVNADLLEFLQ 279 >4IQ4-A nrPDB Length = 456 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 53/268 (19%), Positives = 91/268 (33%), Gaps = 31/268 (11%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 + L+Y+ G G VL+ L + Q L + V+ +D RG+G S P Sbjct: 14 IDLYYEDHGTGTPVVLIHGFPLSG--HSWERQSAALLDAGYRVITYDRRGFGQSSQPTTG 71 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYP-SYIHKMVIWGANAY 167 + ++ A D +++ L + L+G+S G + Y + I + + Sbjct: 72 Y---DYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAAVAFLASLEP 128 Query: 168 VTDEDSMIYEGIRDVSKWS---ERTRKPLEALYG--YDYFARTCEKWVDGIRQFKHLPDG 222 + +G + + A Y ++ F E I + Sbjct: 129 FLLKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSW 188 Query: 223 N-------------------ICRHLLPRVQCPALIVHGEKDPLVPRFH-ADFIHKHVKGS 262 N R +PR+ PALI+HG D +P + A HK + + Sbjct: 189 NTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSA 248 Query: 263 RLHLMPEGKHNLHLRFADEFNKLAEDFL 290 + H L A+E N FL Sbjct: 249 EYVEVEGAPHGLLWTHAEEVNTALLAFL 276 >1A88-A nrPDB Length = 275 Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 54/274 (19%), Positives = 89/274 (32%), Gaps = 35/274 (12%) Query: 47 NGVQLHYQQTGE--GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRP 104 +G + Y+ G G V L + D+ Q+ + V+A D RG+G S Sbjct: 7 DGTNIFYKDWGPRDGLPVVFHHGWPLSAD--DWDNQMLFFLSHGYRVIAHDRRGHGRSDQ 64 Query: 105 PDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKY-PSYIHKMVIWG 163 P + A D L +AL + +G S GG A+ P + K V+ Sbjct: 65 PSTGH---DMDTYAADVAALTEALDLRGAVHIGHSTGGGEVARYVARAEPGRVAKAVLVS 121 Query: 164 ANAYV-----TDEDSMIYEGIRDVSKWSERTRKPLEA------LYGYDYFARTCEK---- 208 A V T+ D + E + R YG++ T + Sbjct: 122 AVPPVMVKSDTNPDGLPLEVFDEFRAALAANRAQFYIDVPSGPFYGFNREGATVSQGLID 181 Query: 209 --WVDG--------IRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVP-RFHADFIHK 257 W+ G + + L R+ P L+ HG D +VP A + Sbjct: 182 HWWLQGMMGAANAHYECIAAFSETDFT-DDLKRIDVPVLVAHGTDDQVVPYADAAPKSAE 240 Query: 258 HVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + + L H + + N F++ Sbjct: 241 LLANATLKSYEGLPHGMLSTHPEVLNPDLLAFVK 274 >1BRO-A nrPDB Length = 277 Score = 141 bits (356), Expect = 3e-34, Method: Composition-based stats. Identities = 54/268 (20%), Positives = 92/268 (34%), Gaps = 31/268 (11%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 + L+Y+ G G VL+ L + Q L + V+ +D RG+G S P Sbjct: 13 IDLYYEDHGTGQPVVLIHGFPLSG--HSWERQSAALLDAGYRVITYDRRGFGQSSQPTTG 70 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYP-SYIHKMVIWGANAY 167 + ++ A D +++ L + L+G+S G + Y + I K+ + Sbjct: 71 Y---DYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAKVAFLASLEP 127 Query: 168 VTDEDSMIYEGIRDVSKWS---ERTRKPLEALYG--YDYFARTCEKWVDGIRQFKHLPDG 222 + +G + + A Y ++ F E I + Sbjct: 128 FLLKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSW 187 Query: 223 N-------------------ICRHLLPRVQCPALIVHGEKDPLVPRFH-ADFIHKHVKGS 262 N R +PR+ PALI+HG D +P + A HK + + Sbjct: 188 NTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSA 247 Query: 263 RLHLMPEGKHNLHLRFADEFNKLAEDFL 290 + H L A+E N FL Sbjct: 248 EYVEVEGAPHGLLWTHAEEVNTALLAFL 275 >1A8Q-A nrPDB Length = 274 Score = 139 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 51/273 (18%), Positives = 97/273 (35%), Gaps = 34/273 (12%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 +GV++ Y+ G+G V + L + QLK + + +A D RG+GHS P Sbjct: 7 DGVEIFYKDWGQGRPVVFIHGWPLNGDA--WQDQLKAVVDAGYRGIAHDRRGHGHSTPVW 64 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPS-YIHKMVIWGA- 164 + F+ A D DL+ L + V+L+ S GG ++ + + V+ A Sbjct: 65 DGY---DFDTFADDLNDLLTDLDLRDVTLVAHSMGGGELARYVGRHGTGRLRSAVLLSAI 121 Query: 165 -----------------------NAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDY 201 N +T+ + + K + + Sbjct: 122 PPVMIKSDKNPDGVPDEVFDALKNGVLTERSQFWKDTAEGFFSANRPGNKVTQGNKDAFW 181 Query: 202 FARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRF-HADFIHKHVK 260 + + G+R + L + P L+VHG+ D +VP + + Sbjct: 182 YMAMAQTIEGGVRCVDAFGYTDFTED-LKKFDIPTLVVHGDDDQVVPIDATGRKSAQIIP 240 Query: 261 GSRLHLMPEGKHNLHLR--FADEFNKLAEDFLQ 291 + L + H + + ++FN+ +FL Sbjct: 241 NAELKVYEGSSHGIAMVPGDKEKFNRDLLEFLN 273 >3KXP-A nrPDB Length = 314 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 57/269 (21%), Positives = 100/269 (37%), Gaps = 25/269 (9%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 S +V + + L+ ++ G G ++L + S F P + L+ + FT +A D RG+G Sbjct: 50 SRRVDIGRITLNVREKGSG--PLMLFFHGITSNSAVFEPLMIRLSDR-FTTIAVDQRGHG 106 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV 160 S P+ + A+ + A D L++ L L+G S G ++ AAAKYP + +V Sbjct: 107 LSDKPETGYEANDY---ADDIAGLIRTLARGHAILVGHSLGARNSVTAAAKYPDLVRSVV 163 Query: 161 IWGANAYVTDE-----------DSMIYEGIRDVSKWSER--TRKPLEALYGYD----YFA 203 Y+ E S ++E I+ V + P +A+ Sbjct: 164 AIDFTPYIETEALDALEARVNAGSQLFEDIKAVEAYLAGRYPNIPADAIRIRAESGYQPV 223 Query: 204 RTCEKWVDGIRQFKHLPDGNICR--HLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG 261 + + G V P LIV GE LV + Sbjct: 224 DGGLRPLASSAAMAQTARGLRSDLVPAYRDVTKPVLIVRGESSKLVSAAALAKTSRLRPD 283 Query: 262 SRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 + ++P H ++ + K +F+ Sbjct: 284 LPVVVVPGADHYVNEVSPEITLKAITNFI 312 >1HKH-A nrPDB Length = 279 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 56/270 (20%), Positives = 98/270 (36%), Gaps = 33/270 (12%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 ++L+Y+ G G VL+ L + Q + L + + V+ +D RG+G S + Sbjct: 13 IELYYEDQGSGQPVVLIHGYPL--DGHSWERQTRELLAQGYRVITYDRRGFGGSSKVNTG 70 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYP-SYIHKMV------- 160 + ++ A D +++ L + V L+G+S G A+Y + K+ Sbjct: 71 Y---DYDTFAADLHTVLETLDLRDVVLVGFSMGTGELARYVARYGHERVAKLAFLASLEP 127 Query: 161 -IWGANAYVTDEDSMIYEGI-----RDVSKWSERTRKPL----EALYGYDYFARTCEKW- 209 + + +++GI D W K E L W Sbjct: 128 FLVQRDDNPEGVPQEVFDGIEAAAKGDRFAWFTDFYKNFYNLDENLGSRISEQAVTGSWN 187 Query: 210 ----VDGIRQFKHLPDG-NICRHLLPRVQC---PALIVHGEKDPLVPRF-HADFIHKHVK 260 + + +P R + V+ P LI+HG KD ++P A H+ V Sbjct: 188 VAIGSAPVAAYAVVPAWIEDFRSDVEAVRAAGKPTLILHGTKDNILPIDATARRFHQAVP 247 Query: 261 GSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 + + H L ADE N + FL Sbjct: 248 EADYVEVEGAPHGLLWTHADEVNAALKTFL 277 >2JBW-A nrPDB Length = 386 Score = 130 bits (326), Expect = 8e-31, Method: Composition-based stats. Identities = 58/227 (25%), Positives = 95/227 (41%), Gaps = 36/227 (15%) Query: 57 GEGDHA-VLLLPGMLGSGETDFGPQLKNLN-KKLFTVVAWDPRGYGHSRPPDRDFPADFF 114 G G H V++L G+ + E F Q++NL + +D G G R A + Sbjct: 148 GPGPHPAVIMLGGLESTKEESF--QMENLVLDRGMATATFDGPGQGEMFEYKR--IAGDY 203 Query: 115 ERDAKDAVDLM---KALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDE 171 E+ VDL+ +A++ + +LG S GG AL +AA P + + WG Sbjct: 204 EKYTSAVVDLLTKLEAIRNDAIGVLGRSLGGNYALKSAACEP-RLAACISWG-------- 254 Query: 172 DSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK-HLPDGNICRHLLP 230 G D+ W T E+ + Y ++ VD + + + H+ R +L Sbjct: 255 ------GFSDLDYWDLETPLTKES---WKYVSK-----VDTLEEARLHVHAALETRDVLS 300 Query: 231 RVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLH--LMPEGKHNLH 275 ++ CP I+HG D VP D + + V L+ + +G H H Sbjct: 301 QIACPTYILHGVHDE-VPLSFVDTVLELVPAEHLNLVVEKDGDHCCH 346 >4UHD-A nrPDB Length = 282 Score = 126 bits (317), Expect = 8e-30, Method: Composition-based stats. Identities = 52/260 (20%), Positives = 97/260 (37%), Gaps = 23/260 (8%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 ++L ++ TG G +L+ L T + Q + L + F V+ D RG+G S+ Sbjct: 16 IELAFEDTGTGLPVLLVHGFPL--DRTMWKAQREELCDE-FRVIVPDLRGFGESQVIPGV 72 Query: 109 FPADFFERDAKDAVDLMKALKF-KKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY 167 + A D L L K+ L G S GG A A KY + +++ A Sbjct: 73 ATMEAM---ADDLAGLCNHLGLTGKIVLGGLSMGGYVAFAFARKYRDRLAGLILCDTRAR 129 Query: 168 VTDEDSMIYEGIRDVSKWSERTRKPLEALYGY---DYFARTCEKWVDGIRQ--FKHLPDG 222 ++ E E + + R + ++ IRQ P+G Sbjct: 130 PDSPEAKENRRRVAERVRREGPGFIAEEMIPRLCCESTFRNHPEVIEKIRQMILSAPPEG 189 Query: 223 -----------NICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGK 271 LLP + CP L++ G+ D + P + + + + S+ ++P+ Sbjct: 190 VAAAALGMAERPDSTDLLPALSCPTLVLVGQFDAISPPEEMEAMARTIPQSQFVVIPDAG 249 Query: 272 HNLHLRFADEFNKLAEDFLQ 291 H + + + ++L+ Sbjct: 250 HLPPMEQPERVTQAIREWLR 269 >3WMR-A nrPDB Length = 315 Score = 121 bits (303), Expect = 4e-28, Method: Composition-based stats. Identities = 67/310 (21%), Positives = 114/310 (36%), Gaps = 52/310 (16%) Query: 23 GIHV---PRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGP 79 G H+ P A FG T +V + LH G V+LL G GS D+ Sbjct: 14 GRHMSKPPSAKGTVPFGQYRTWYRVTGD---LH-----SGKPPVVLLHGGPGST-HDYLL 64 Query: 80 QLKNLNKKLFTVVAWDPRGYGHSRP-PDRDFPADFFERDAKDAVDLMKALKFK-KVSLLG 137 + +L + + VV +D G G S P++ + + +L+ L L G Sbjct: 65 AMTSLTEAGWPVVHYDQLGNGGSTHLPEKGEDFWTVQLFEDELDNLLNQLGIAGDYVLFG 124 Query: 138 WSDGGITALIAAAKYPSYIHKMVIWGANAYVT-----------------DEDSMIYEGIR 180 S GG+ + AA+ P+ + +V+ A A + E + +E R Sbjct: 125 QSWGGMLGSVHAARRPAGLRGLVVANAPASMKIWLQEMARLRALLPPDVQETLLKHEAAR 184 Query: 181 --DVSKWSERTRK--------------PLEALYGYDYFARTCEKWVDGIRQF---KHLPD 221 D ++ R A + Y T ++G +F L D Sbjct: 185 TTDTEEYFHAMRAFYDRHVCRIVPWPRDFAATFMEIYNDPTVYTTMNGPNEFHVIGTLRD 244 Query: 222 GNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADE 281 ++ LP +Q P +++ G D P F+ V R ++ H HL + Sbjct: 245 WSV-EDCLPDIQVPTMVLIGRHDEATPATVKPFL-DLVPDVRYEVLENSSHVPHLEEPER 302 Query: 282 FNKLAEDFLQ 291 F+++ D+L+ Sbjct: 303 FHEVMIDYLE 312 >3HSS-A nrPDB Length = 293 Score = 117 bits (294), Expect = 4e-27, Method: Composition-based stats. Identities = 42/260 (16%), Positives = 77/260 (29%), Gaps = 24/260 (9%) Query: 49 VQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 + L Y G GD V + G G+G T Q+ + + +D RG G + + Sbjct: 33 INLAYDDNGTGDPVVF-IAGRGGAGRTWHPHQVPAFLAAGYRCITFDNRGIGATE----N 87 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYV 168 + D L++ L ++G S G A P + V+ + Sbjct: 88 AEGFTTQTMVADTAALIETLDIAPARVVGVSMGAFIAQELMVVAPELVSSAVLMATRGRL 147 Query: 169 --------TDEDSMIYEGIRDVSKWSERTR--KPLEALYGYDYFARTCEKWVDGIRQFKH 218 E + G++ + R R + D A + + K Sbjct: 148 DRARQFFNKAEAELYDSGVQLPPTYDARARLLENFSRKTLNDDVAVGDWIAMFSMWPIKS 207 Query: 219 LPDGNICRHLLPR---------VQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPE 269 P P+ + P L++ D + P + + + R +P+ Sbjct: 208 TPGLRCQLDCAPQTNRLPAYRNIAAPVLVIGFADDVVTPPYLGREVADALPNGRYLQIPD 267 Query: 270 GKHNLHLRFADEFNKLAEDF 289 H + N F Sbjct: 268 AGHLGFFERPEAVNTAMLKF 287 >4FBL-A nrPDB Length = 281 Score = 117 bits (293), Expect = 5e-27, Method: Composition-based stats. Identities = 55/258 (21%), Positives = 98/258 (37%), Gaps = 31/258 (12%) Query: 22 PGIHVPRAGPAAAFGTSVTSAKVAV-NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQ 80 P + P G+ +++ + V G + Y G ++ F Sbjct: 14 PRSGDAQQRPRERSGSGMSTTPLQVLPGAEPLY-SVGSRIGVLVSHGFTGSPQSMRFLA- 71 Query: 81 LKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKD-AVDLMKALKFKK-----VS 134 + + +TV G+G PA+ A D D++ A+++ + + Sbjct: 72 -EGFARAGYTVATPRLTGHG-------TTPAEMAASTASDWTADIVAAMRWLEERCDVLF 123 Query: 135 LLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLE 194 + G S GG + AA ++P I NA + E D++ + P E Sbjct: 124 MTGLSMGGALTVWAAGQFPERFAG--IMPINAALRMESP-------DLAALAFNPDAPAE 174 Query: 195 AL-YGYDYFARTCEKW---VDGIRQFKHLPD-GNICRHLLPRVQCPALIVHGEKDPLVPR 249 G D A ++ V + KHL G + LLPRV+CPALI+ +D +VP Sbjct: 175 LPGIGSDIKAEGVKELAYPVTPVPAIKHLITIGAVAEMLLPRVKCPALIIQSREDHVVPP 234 Query: 250 FHADFIHKHVKGSRLHLM 267 + + I+ + + L+ Sbjct: 235 HNGELIYNGIGSTEKELL 252 >4Y2Y-A nrPDB Length = 561 Score = 117 bits (293), Expect = 6e-27, Method: Composition-based stats. Identities = 49/324 (15%), Positives = 99/324 (30%), Gaps = 60/324 (18%) Query: 24 IHVPRAGPAAAFGTSVTSAKVAVN-GVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 ++ P P + + ++ V V V+LH+ + G G L + Q+ Sbjct: 222 LNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPES--WYSWRYQIP 279 Query: 83 NLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG 142 L + + V+A D +GYG S P E K+ V + L + +G GG Sbjct: 280 ALAQAGYRVLAMDMKGYGESSAPPEIEEY-CMEVLCKEMVTFLDKLGLSQAVFIGHDWGG 338 Query: 143 ITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSER-------------- 188 + A YP + + + + E I+ + + Sbjct: 339 MLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELE 398 Query: 189 ----------TRKPLEALYGYDYFARTCEKWVDGIRQ----------------------- 215 R E++ +V+ + Sbjct: 399 QNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSG 458 Query: 216 FKHLPDGN---------ICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHL 266 F+ + C+ L ++ PAL+V EKD ++ + + + + Sbjct: 459 FRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGH 518 Query: 267 MPEGKHNLHLRFADEFNKLAEDFL 290 + + H + E N++ +L Sbjct: 519 IEDCGHWTQMDKPTEVNQILIKWL 542 >4RNC-A nrPDB Length = 310 Score = 114 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 53/269 (19%), Positives = 87/269 (32%), Gaps = 26/269 (9%) Query: 44 VAVNGVQLHYQQTG--EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 V+V+G + Y+ TG G VLL S +G Q+ + ++A D RG+G+ Sbjct: 28 VSVDGTSIVYRVTGNSAGTPLVLLHGWAQSS--QCWGEQVLADLAADYRLIAVDLRGHGY 85 Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKF-KKVSLLGWSDGGITALIAAAKYPS-YIHKM 159 S P+ + D A D ++ A + LLGWS GG+ A + + + Sbjct: 86 SDAPESGY--DDSANWAGDVAAVLAAEGVTENAILLGWSYGGLVICDYLAAHGTGAVAGA 143 Query: 160 VIWGA------------------NAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDY 201 V+ GA +A E IR + + P E Sbjct: 144 VLVGAITSIGRGEKGGKVGSAMRSAVPGAMSEDPREAIRALGAFGNALTGPPEGKGAASQ 203 Query: 202 FARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG 261 + LL + P L++HG D +V + + Sbjct: 204 ALFGYSLSTRPRVRAALFNRAVGHDELLRNLDIPVLVLHGTDDSVVDVSAGKHAEELIPK 263 Query: 262 SRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 S+ H + F F+ Sbjct: 264 SQASYWVGCNHGPFVEDPTRFVSEVRTFI 292 >5Y6Y-B nrPDB Length = 326 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 54/313 (17%), Positives = 90/313 (28%), Gaps = 66/313 (21%) Query: 42 AKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 V VNG+++H + GEG + L + Q+ L+ + + VA D RGYG Sbjct: 7 RTVEVNGIKMHVAEKGEGPVVLFLHGFPEL--WYSWRHQILALSSRGYRAVAPDLRGYGD 64 Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161 + P F D + L+ L +V L+ G I +P + V Sbjct: 65 TEAPVSISSYTGF-HIVGDLIALIDLLGVDQVFLVAHDWGAIIGWYLCTFHPDRVKAYVC 123 Query: 162 WGANAYVTDEDSMIYEGIRDV---SKWSERTRKPLE-----ALYGYDYFARTCEKWVDG- 212 D + + +R + + R +KP E A G +Y + Sbjct: 124 LSVPLLHRDPNIRTVDAMRAMYGDDYYICRFQKPGEMEAQMAEVGTEYVLKNILTTRKPG 183 Query: 213 --------------IRQFKHLPDGNICRHLL----------------------------- 229 LP L Sbjct: 184 PPIFPKGEYGTGFNPDMPNSLPSWLTQDDLAYYVSKYEKTGFTGPLNYYRNMNLNWELTA 243 Query: 230 ----PRVQCPALIVHGEKDPLVPR------FHADFIHKHVKG-SRLHLMPEGKHNLHLRF 278 ++Q P + GE D + H + V + + H + Sbjct: 244 PWSGGKIQVPVKFITGELDNVYTSLNMKEYIHGGGFKQDVPNLEEVIVQKNVAHFNNQEA 303 Query: 279 ADEFNKLAEDFLQ 291 A+E N DF++ Sbjct: 304 AEEINNHIYDFIK 316 >4NVR-A nrPDB Length = 307 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 45/281 (16%), Positives = 80/281 (28%), Gaps = 40/281 (14%) Query: 47 NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD 106 NG+ + G G VLL ++ + TV+ D RGYG S P Sbjct: 28 NGLTVRVAIGGSGSPLVLLHGHPQNHTTW---RKVAPTLAQNHTVILPDLRGYGDSDKPT 84 Query: 107 RDFPADFFER--DAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA 164 D + + A+D V LM AL F + + +G GG A YP + Sbjct: 85 SDPAHRTYSKRTMAQDIVMLMDALGFSRFAFVGHDRGGRVGHRLALDYPDRVTCCTFIDI 144 Query: 165 NAYVTDEDS---------MIYEGIRDVSKWSERTRKPLEALYGYDYFARTCE-------- 207 T + + E A + + + + Sbjct: 145 APTATMYALTDKSFATRYFWWFFLIQPFPLPETMIAHDPAFFLRKHISGQLKIEGATSQE 204 Query: 208 ----------------KWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFH 251 + R + + R++CP ++ G + ++ Sbjct: 205 AFNEYLRCYQNPEMIHAICEDYRAAATIDLDDDAADTSARIRCPLQLLWGGLGTVGQLYN 264 Query: 252 ADFIHKHVK-GSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 K + +P H+ + F + + FL Sbjct: 265 VVGTWKEKALNVQGEALP-CGHSPQEECPEYFIQKLQSFLH 304 >4CCY-A nrPDB Length = 296 Score = 101 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 47/254 (18%), Positives = 84/254 (33%), Gaps = 18/254 (7%) Query: 50 QLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF 109 + H +G D L+L + P + + + F A D G + P Sbjct: 43 KTHIIASGPKDAPSLILLHGGLFSSAMWYPNIAAWSSQ-FRTYAVDIIGDKNKSIP--SA 99 Query: 110 PADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVT 169 + A+ D+ +L + L G S GG + + P + + V+ Sbjct: 100 AMETRADFAEWMKDVFDSLGLETAHLAGLSLGGSHIVNFLLRAPERVERAVVISPAEAFI 159 Query: 170 DEDSMIYEGIRDVS---------KWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLP 220 +Y+ +++ KW L L A +W D R K Sbjct: 160 SFHPDVYKYAAELTGARGAESYIKWITGDSYDLHPLLQRQIVAGV--EWQDEQRSLKPTE 217 Query: 221 DG---NICRHLLPRVQCPALIVHGEKDPLVPRFHA-DFIHKHVKGSRLHLMPEGKHNLHL 276 +G L +Q P L++ GE + + + A + V G + ++ H L L Sbjct: 218 NGFPYVFTDQELKSIQVPVLLMFGEHEAMYHQQMAFERASVLVPGIQAEIVKNAGHLLSL 277 Query: 277 RFADEFNKLAEDFL 290 + N+ FL Sbjct: 278 EQPEYVNQRVLSFL 291 >2XMZ-A nrPDB Length = 269 Score = 98.3 bits (243), Expect = 3e-21, Method: Composition-based stats. Identities = 49/265 (18%), Positives = 91/265 (34%), Gaps = 30/265 (11%) Query: 52 HYQQTGEGDHA--VLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH-SRPPDRD 108 HY+ VL+ S + ++ + V+ D G+G D Sbjct: 5 HYKFYEANVETNQVLVFLHGFLSDSRTYHNHIEKFTD-NYHVITIDLPGHGEDQSSMDET 63 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYV 168 + D+ ++ K K ++L G+S GG AL A I +++ + + Sbjct: 64 WNFDYITTLLD---RILDKYKDKSITLFGYSMGGRVALYYAINGHIPISNLILESTSPGI 120 Query: 169 TDEDSMIYEGIRD---------------VSKWSERT--RKPLEALYGYDYFARTCEKWVD 211 +E + + + D V+ W + + LE + R Sbjct: 121 KEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQLELPVEIQHQIRQQRLSQS 180 Query: 212 GIRQFKHLPDG-----NICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHL 266 + K L D L ++ P LI+ GE D A + + S+ L Sbjct: 181 PHKMAKALRDYGTGQMPNLWPRLKEIKVPTLILAGEYDEKF-VQIAKKMANLIPNSKCKL 239 Query: 267 MPEGKHNLHLRFADEFNKLAEDFLQ 291 + H +H+ +DEF+ + FL+ Sbjct: 240 ISATGHTIHVEDSDEFDTMILGFLK 264 >4CCW-A nrPDB Length = 299 Score = 97.2 bits (240), Expect = 8e-21, Method: Composition-based stats. Identities = 44/255 (17%), Positives = 79/255 (30%), Gaps = 18/255 (7%) Query: 50 QLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF 109 Q H +G D L+L T + P + + + K + A D G + P+ Sbjct: 43 QTHVIASGPEDAPPLVLLHGALFSSTMWYPNIADWSSK-YRTYAVDIIGDKNKSIPENL- 100 Query: 110 PADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHK-MVIWGANAYV 168 + A +D+ L +K ++G S GG+ + + P + ++ A ++ Sbjct: 101 -SGTRTDYANWLLDVFDNLGIEKSHMIGLSLGGLHTMNFLLRMPERVKSAAILSPAETFL 159 Query: 169 TDEDSMI--------YEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLP 220 G+ W T + + F W DG R Sbjct: 160 PFHHDFYKYALGLTASNGVEKFLNWM-MTDQNVLHPIFVKQFQAGV-MWQDGSRNPNPKA 217 Query: 221 DG---NICRHLLPRVQCPALIVHGEKDPLVPRFHAD-FIHKHVKGSRLHLMPEGKHNLHL 276 DG L + P L++ GE + + A V ++ H L + Sbjct: 218 DGFPYVFTDEELRSARVPILLLLGEHEVIYDPHSALHRASSFVPDIEAEVIKNAGHVLSM 277 Query: 277 RFADEFNKLAEDFLQ 291 N+ F Sbjct: 278 EQPAYVNERVMRFFN 292 >4HTA-A nrPDB Length = 288 Score = 96.8 bits (239), Expect = 9e-21, Method: Composition-based stats. Identities = 51/254 (20%), Positives = 102/254 (40%), Gaps = 21/254 (8%) Query: 57 GEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF-PADFFE 115 G G+ ++L G G+ ++ + + +L + VV +D G G + P DF E Sbjct: 32 GSGEATIVLGHG-FGTDQSVWKHLVPHLVDD-YRVVLYDNMGAGTTNPDYFDFDRYSNLE 89 Query: 116 RDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANA-YVTDEDSM 174 + D + +++ LK + +G S + ++A+ P K+V+ A+ YV D D Sbjct: 90 GYSFDLIAILEDLKIESCIFVGHSVSAMIGVLASLNRPDLFSKIVMISASPRYVNDVDYQ 149 Query: 175 IYEGIRDVSKWSERTRKPLEA--------LYGYDYFARTCEKWVDGIRQFK--------H 218 D+++ E R +A G D + +++ + + Sbjct: 150 GGFEQEDLNQLFEAIRSNYKAWCLGFAPLAVGGDMDSIAVQEFSRTLFNMRPDIALSVGQ 209 Query: 219 LPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVK-GSRLHLMPEGKHNLHLR 277 + R +LP V P I+ KD VP ++++H ++ S + ++P H L Sbjct: 210 TIFQSDMRQILPFVTVPCHILQSVKDLAVPVVVSEYLHANLGCESVVEVIPSDGHLPQLS 269 Query: 278 FADEFNKLAEDFLQ 291 D + ++ Sbjct: 270 SPDSVIPVILRHIR 283 >1CR6-A nrPDB Length = 554 Score = 93.3 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 3/141 (2%) Query: 48 GVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDR 107 G++LH+ + G G L + Q+ L + F V+A D +GYG S P Sbjct: 245 GIRLHFVEMGSGPALCLCHGFPES--WFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPE 302 Query: 108 DFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY 167 E K+ V + L + +G G+ A YP + + Sbjct: 303 IEEY-AMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFM 361 Query: 168 VTDEDSMIYEGIRDVSKWSER 188 D D + IR + ++ + Sbjct: 362 PPDPDVSPMKVIRSIPVFNYQ 382 Score = 47.1 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 28/61 (45%) Query: 231 RVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 ++ PAL+V EKD ++ + + K + + + + H + E N++ +L Sbjct: 482 KILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWL 541 Query: 291 Q 291 Q Sbjct: 542 Q 542 >1Q0R-A nrPDB Length = 298 Score = 92.1 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 45/278 (16%), Positives = 81/278 (29%), Gaps = 42/278 (15%) Query: 39 VTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQL-KNLNKKLFTVVAWDPR 97 ++ V V+L G+ LLL + + + L V+ +D R Sbjct: 1 MSERIVPSGDVELWSDDFGDPADPALLLVMGGNLSALGWPDEFARRLADGGLHVIRYDHR 60 Query: 98 GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIH 157 G S D F A DAV ++ + ++G S G + A + + Sbjct: 61 DTGRSTTRDFAAHPYGFGELAADAVAVLDGWGVDRAHVVGLSMGATITQVIALDHHDRLS 120 Query: 158 KM-VIWGANAYV--TDEDSMIYEGIRDVSKWSERTRKPLEALYGYDY--------FARTC 206 + ++ G + + G + + L+AL + A+ Sbjct: 121 SLTMLLGGGLDIDFDANIERVMRGEPTLDGLPGPQQPFLDALALMNQPAEGRAAEVAKRV 180 Query: 207 EKW------------------------------VDGIRQFKHLPDGNICRHLLPRVQCPA 236 KW + + L V P Sbjct: 181 SKWRILSGTGVPFDDAEYARWEERAIDHAGGVLAEPYAHYSLTLPPPSRAAELREVTVPT 240 Query: 237 LIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNL 274 L++ E DP+ P H + + +RL +P H L Sbjct: 241 LVIQAEHDPIAPAPHGKHLAGLIPTARLAEIPGMGHAL 278 >5YHP-A nrPDB Length = 355 Score = 92.1 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 53/347 (15%), Positives = 100/347 (28%), Gaps = 91/347 (26%) Query: 26 VPRAGPAAAFGT------------SVTSAKVAVNGVQLH-----------YQQTG--EGD 60 + G ++TS A+ + H ++ G +G Sbjct: 12 MASMTGGQQMGRDLYDDDDKDHPFTMTSLFAAIQPYKTHLLRVSPLHRLSIKEYGNPQGK 71 Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKD 120 V L G G + N + +V +D RG G S P + + +D Sbjct: 72 PVVFLHGGPGGGAS---DSDARRFNPTTYRIVLFDQRGSGEST-PASCLEDNTTQALVED 127 Query: 121 AVDLMKALKFKKV-SLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGI 179 + + L+ + G S G AL A +P+ + + + G E Y+G Sbjct: 128 IEKIREFLQVGAAWHVFGGSWGSTLALAYAQAHPARVKSLTLRGIFTLRKKELDFFYQGP 187 Query: 180 R----------------DVSKWSERTRKPLEALYGYD----------------------- 200 V++ + + E L G D Sbjct: 188 GSSFVFPEYWEEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGRAWSRWEMATSRLHV 247 Query: 201 ----YFARTCEKWVDGIRQFKH---------LPDGNICRHLLPRVQ-CPALIVHGEKDPL 246 + D + + + + ++ PA+IV G D + Sbjct: 248 DPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKISHIPAVIVQGRYDMV 307 Query: 247 VPRFHADFIHKHVKGSRLHLMPEGKHN--------LHLRFADEFNKL 285 P A + K ++ ++P+ H+ + +EF KL Sbjct: 308 CPITTAYELTKLWPEAKFVVIPDAGHSAIEAGTEKALVEATEEFAKL 354 >1M33-A nrPDB Length = 258 Score = 90.6 bits (223), Expect = 7e-19, Method: Composition-based stats. Identities = 54/259 (20%), Positives = 86/259 (33%), Gaps = 32/259 (12%) Query: 50 QLHYQQTGEGD-HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD 108 + +Q G+G+ H VLL L + + FT+ D G+G SR Sbjct: 3 NIWWQTKGQGNVHLVLLHGWGLNAEVW---RCIDEELSSHFTLHLVDLPGFGRSR----- 54 Query: 109 FPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYV 168 F D + + K LGWS GG+ A A +P + +V ++ Sbjct: 55 ---GFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVRALVTVASSPCF 111 Query: 169 TDEDSMI-------YEGIRDVSKWSERTRKPLEAL--YGYDYFARTCEKW---------- 209 + D + +S +RT + AL G + + Sbjct: 112 SARDEWPGIKPDVLAGFQQQLSDDQQRTVERFLALQTMGTETARQDARALKKTVLALPMP 171 Query: 210 -VDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMP 268 VD + + R L V P L ++G D LVPR + K S ++ Sbjct: 172 EVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFA 231 Query: 269 EGKHNLHLRFADEFNKLAE 287 + H + EF L Sbjct: 232 KAAHAPFISHPAEFCHLLV 250 >1QTR-A nrPDB Length = 317 Score = 87.9 bits (216), Expect = 5e-18, Method: Composition-based stats. Identities = 53/277 (19%), Positives = 94/277 (33%), Gaps = 54/277 (19%) Query: 47 NGVQLHYQQTGEGD-HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPP 105 +G +++++ +G + + + G G G + QL + + + V+ +D RG G SR P Sbjct: 23 DGHRIYWELSGNPNGKPAVFIHGGPGGGISPHHRQL--FDPERYKVLLFDQRGCGRSR-P 79 Query: 106 DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165 + D L + ++ + G S G AL A +P + +MV+ G Sbjct: 80 HASLDNNTTWHLVADIERLREMAGVEQWLVFGGSWGSTLALAYAQTHPERVSEMVLRGIF 139 Query: 166 AYVTDEDSMIYEG----------IRDVSKWSERTRKPLEALY------------------ 197 Y+ R +S S+ RK + A Y Sbjct: 140 TLRKQRLHWYYQDGASRFFPEKWERVLSILSDDERKDVIAAYRQRLTSADPQVQLEAAKL 199 Query: 198 --------------------GYDYFARTCEKWVDGIRQ-FKHLPDGNICRHLLPRVQ-CP 235 G D FA + + L + +P ++ P Sbjct: 200 WSVWEGETVTLLPSRESASFGEDDFALAFARIENHYFTHLGFLESDDQLLRNVPLIRHIP 259 Query: 236 ALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKH 272 A+IVHG D +A + K + LH++ H Sbjct: 260 AVIVHGRYDMACQVQNAWDLAKAWPEAELHIVEGAGH 296 >4IH4-A nrPDB Length = 267 Score = 87.1 bits (214), Expect = 7e-18, Method: Composition-based stats. Identities = 46/262 (17%), Positives = 92/262 (35%), Gaps = 30/262 (11%) Query: 51 LHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF- 109 L+ + G GD + L G G+ ++ + L + + VV +D G P DF Sbjct: 10 LNVRVVGTGDRILFLAHG-FGTDQSAWHLILPYFT-QNYRVVLYDLVCAGSVNPDYFDFN 67 Query: 110 PADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY-V 168 + D ++++ +L + + +G S + +IA+ + P K+++ G + + Sbjct: 68 RYTTLDPYVDDLLNIVDSLGIQNCAYVGHSVSAMIGIIASIRRPELFSKLILIGFSPRFL 127 Query: 169 TDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNI---- 224 DED ++ K EA + + D + Sbjct: 128 NDEDYHGGFEEGEIEKVFSAMEANYEA---WVHGFAPLAVGADVPAAVREFSRTLFNMRP 184 Query: 225 --------------CRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG-SRLHLMPE 269 R +L V+ P ++ KD VP A+++ H+ G + + + Sbjct: 185 DISLFVSRTVFNSDLRGVLGLVRVPTCVIQTAKDVSVPASVAEYLRSHLGGDTTVETLKT 244 Query: 270 GKHNLHLRFADEFNKLAEDFLQ 291 H L + FL+ Sbjct: 245 EGHLPQLSAPAQ----LAQFLR 262 >3RLI-A nrPDB Length = 270 Score = 85.2 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 40/233 (17%), Positives = 85/233 (36%), Gaps = 10/233 (4%) Query: 36 GTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWD 95 G+ ++ ++G + Y + G +LL P + K +TV Sbjct: 18 GSHMSEQYPVLSGAEPFYAENG---PVGVLLVHGFTGTPHSMRPLAEAYAKAGYTVCLPR 74 Query: 96 PRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSY 155 +G+G + ++ +K + + + + G S GG L A +P Sbjct: 75 LKGHGTHYEDMERTTFHDWVASVEEGYGWLKQ-RCQTIFVTGLSMGGTLTLYLAEHHPD- 132 Query: 156 IHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQ 215 I +V A + + + G ++ ++ + L+ + + + Q Sbjct: 133 ICGIVPINAAVDIPAIAAGMTGG-GELPRYLDSIGSDLKNPDVKE--LAYEKTPTASLLQ 189 Query: 216 FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMP 268 L + L R+ CPALI ++D +VP +AD I + + + ++ Sbjct: 190 LARLMA--QTKAKLDRIVCPALIFVSDEDHVVPPGNADIIFQGISSTEKEIVR 240 >2E3J-A nrPDB Length = 356 Score = 84.8 bits (208), Expect = 4e-17, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 55/174 (31%), Gaps = 6/174 (3%) Query: 48 GVQLHYQQTGEGDH--AVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPP 105 G ++H D +++L + Q+ L + VVA D RGYG S Sbjct: 12 GTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKY 71 Query: 106 DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKM--VIWG 163 R A + D V ++ + ++ ++G G A A +P + + Sbjct: 72 -RVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVP 130 Query: 164 ANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 217 G R S + P Y DYFA + + Sbjct: 131 FAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQ-DYFAVQDGIITEIEEDLR 183 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 65/204 (31%), Gaps = 29/204 (14%) Query: 105 PDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDG-----GITALIAAAKYP-SYIHK 158 P R + D+F ++ + L+ GW G ++AA K Sbjct: 159 PGRVWYQDYFAVQDGIITEIEEDLR-------GWLLGLTYTVSGEGMMAATKAAVDAGVD 211 Query: 159 MVIWGANAYVTDEDSMIYEG--IRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQF 216 + + + EG ++D + E Y G F Sbjct: 212 LESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSF 271 Query: 217 KHLPDGNICRHLLPR-----VQCPALIVHGEKDPLVPRFHA----DFIHKHVKGSR-LHL 266 H D + H L + PAL + G+ D V + H+ + R H+ Sbjct: 272 YHNIDND--WHDLADQQGKPLTPPALFIGGQYD--VGTIWGAQAIERAHEVMPNYRGTHM 327 Query: 267 MPEGKHNLHLRFADEFNKLAEDFL 290 + + H + +E N+L DFL Sbjct: 328 IADVGHWIQQEAPEETNRLLLDFL 351 >5UXZ-A nrPDB Length = 307 Score = 84.1 bits (206), Expect = 6e-17, Method: Composition-based stats. Identities = 44/274 (16%), Positives = 80/274 (29%), Gaps = 43/274 (15%) Query: 43 KVAVNGVQLHYQQTGE--GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 V V G ++HY G G + L S + +A D G G Sbjct: 11 YVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYVW---RNIIPHVAPTHRCIAPDLIGMG 67 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMV 160 S PD + D R ++AL ++V L+ G A + P + + Sbjct: 68 KSDKPDLGYFFDDHVRFMDAF---IEALGLEEVVLVIHDWGSALGFHWAKRNPERVKGIA 124 Query: 161 IWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTC-------------- 206 + D E R+ + T + + + F Sbjct: 125 FMEFIRPIPTWDEWP-EFARETFQAFRTTDVGRKLIIDQNVFIEGTLPMGVVRPLTEVEM 183 Query: 207 ----EKWVDGIRQ------FKHLPDGNICRHLLPRVQ----------CPALIVHGEKDPL 246 E +++ + + LP +++ V+ P L+ G L Sbjct: 184 DHYREPFLNPVDREPLWRFPNELPIAGEPANIVALVEEYMDWLHQSPVPKLLFWGTPGVL 243 Query: 247 VPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFAD 280 +P A + K + + + G + L D Sbjct: 244 IPPAEAARLAKSLPNCKAVDIGPGLNLLQEDNPD 277 >4NMW-A nrPDB Length = 259 Score = 84.1 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 48/259 (18%), Positives = 77/259 (29%), Gaps = 34/259 (13%) Query: 51 LHYQQTGEGD-HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF 109 + +Q GEG+ H VLL L + ++ FT+ D GYG S F Sbjct: 7 IWWQTYGEGNCHLVLLHGWGLNAEVW---HCIREELGSHFTLHLVDLPGYGRSS----GF 59 Query: 110 PADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVT 169 A E + LGWS GG+ A A +P + +V ++ + Sbjct: 60 GAMTLEEMTAQVAKNAP----DQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFS 115 Query: 170 DEDSMI---------------------YEGIRDVSKWSERTRKPLEALYGYDYFARTCEK 208 + E + T + A+ Sbjct: 116 AREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPD 175 Query: 209 WVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMP 268 + L ++ R L V P L ++G D LVPR + S +M Sbjct: 176 VEVLNGGLEILKTVDL-REALKNVNMPFLRLYGYLDGLVPRKIVPLLDTLWPHSTSQIMA 234 Query: 269 EGKHNLHLRFADEFNKLAE 287 + H + F + Sbjct: 235 KAAHAPFISHPAAFCQALM 253 >1AZW-A nrPDB Length = 313 Score = 83.3 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 92/293 (31%), Gaps = 57/293 (19%) Query: 47 NGVQLHYQQTGEGD-HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPP 105 + L+++Q G V++L G G G D + + + +V +D RG G S P Sbjct: 20 DRHTLYFEQCGNPHGKPVVMLHGGPGGGCNDKMRRFHD--PAKYRIVLFDQRGSGRST-P 76 Query: 106 DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165 D + D L L + + G S G AL A +P + ++V+ G Sbjct: 77 HADLVDNTTWDLVADIERLRTHLGVDRWQVFGGSWGSTLALAYAQTHPQQVTELVLRGIF 136 Query: 166 AYVTDEDSMIYE-----------------------------GIRDVSKWSERTRKPLEAL 196 E Y+ R ++ E TR Sbjct: 137 LLRRFELEWFYQEGASRLFPDAWEHYLNAIPPVERADLMSAFHRRLTSDDEATRLAAAKA 196 Query: 197 Y----GYDYFARTCEKWVDGIR-----------QFKHLPDGNIC-------RHLLPRVQC 234 + G F E +V G + + +G R Sbjct: 197 WSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENHYFVNGGFFEVEDQLLRDAHRIADI 256 Query: 235 PALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAE 287 P +IVHG D + P A +HK ++L + P H+ + + L Sbjct: 257 PGVIVHGRYDVVCPLQSAWDLHKAWPKAQLQISPASGHSAF--EPENVDALVR 307 >6AP7-A nrPDB Length = 269 Score = 80.6 bits (197), Expect = 6e-16, Method: Composition-based stats. Identities = 51/261 (19%), Positives = 94/261 (36%), Gaps = 30/261 (11%) Query: 51 LHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPD---- 106 L+ + G G+ ++L G G+ ++ + L + + VV +D G S PD Sbjct: 11 LNVRVVGSGERVLVLAHG-FGTDQSAWNRILPFFLRD-YRVVLYDLVCAG-SVNPDFFDF 67 Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANA 166 R + + D + ++ AL + + +G S + ++A+ + P K+++ GA+ Sbjct: 68 RRYT--TLDPYVDDLLHILDALGIDQCAYVGHSVSAMIGILASIRRPELFSKLILIGASP 125 Query: 167 Y-VTDEDSMIYEGIRDVSKWSERTRKPLEA--------LYGYDYFARTCEKWVDGIRQ-- 215 + DED ++ K EA G D A E Sbjct: 126 RFLNDEDYHGGFEQGEIEKVFSAMEANYEAWVNGFAPLAVGADVPAAVREFSRTLFNMRP 185 Query: 216 -----FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG-SRLHLMPE 269 + R +L V+ P I +D VP A ++ H+ G + +H + Sbjct: 186 DITLFVSRTVFNSDMRGVLGLVKVPCHIFQTARDHSVPASVATYLKNHLGGKNTVHWLNI 245 Query: 270 GKHNLHLRFA----DEFNKLA 286 H HL E + Sbjct: 246 EGHLPHLSAPTLLAQELRRAL 266 >2YYS-A nrPDB Length = 286 Score = 80.6 bits (197), Expect = 6e-16, Method: Composition-based stats. Identities = 47/265 (17%), Positives = 91/265 (34%), Gaps = 25/265 (9%) Query: 43 KVAVNGVQLHYQQTGEGD-HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 V V +L+ + G + A+ +L G G L++ + F VV +D RG G Sbjct: 7 YVPVGEAELYVEDVGPVEGPALFVLHGGPGGNAYVLREGLQDYL-EGFRVVYFDQRGSGR 65 Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161 S +D + +D + L +AL ++ LL G + AL ++P +++ Sbjct: 66 SLELPQDPRLFTVDALVEDTLLLAEALGVERFGLLAHGFGAVVALEVLRRFPQAEGAILL 125 Query: 162 WG-----------ANAYVTDEDSMIYEGIRDVSKWSERTR-------KPLEALYGYDYFA 203 A A E +++ K E Y++ A Sbjct: 126 APWVNFPWLAARLAEAAGLAPLPDPEENLKEALKREEPKALFDRLMFPTPRGRMAYEWLA 185 Query: 204 RTCEKWVDGIRQFKHLPDGNICRHLLPRV---QCPALIVHGEKDPLVPRFHADFIHKHVK 260 L +G P + + P ++ GE+D + + + Sbjct: 186 EGAGILGSDAPGLAFLRNGLWRLDYTPYLTPERRPLYVLVGERDGTSYPYAEEVASRL-- 243 Query: 261 GSRLHLMPEGKHNLHLRFADEFNKL 285 + + ++PE H L + + F + Sbjct: 244 RAPIRVLPEAGHYLWIDAPEAFEEA 268 >5XKS-A nrPDB Length = 256 Score = 80.2 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 42/241 (17%), Positives = 88/241 (36%), Gaps = 14/241 (5%) Query: 39 VTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG 98 +T V G + + + G ++L P + ++ +TV +G Sbjct: 1 MTETYPVVKGAEPFFFE-GNDIGILVLHGFTGSP--QSMRPLGEAYHEAGYTVCGPRLKG 57 Query: 99 YGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHK 158 +G + + + +K + + + G S GG L A +P Sbjct: 58 HGTHYEDMEKTTCQDWIDSVEAGYEWLKN-RCGTIFVTGLSMGGTLTLYMAEHHPEICG- 115 Query: 159 MVIWGANAYVTDED-SMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 217 I NA + + G+ D+ ++ + ++ + + IRQ Sbjct: 116 --IAPINAAINMPALAGALAGVGDLPRFLDAIGSDIKKPGVKE--LAYEKTPAASIRQIV 171 Query: 218 HLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS--RLHLMPEGKHNLH 275 L + L ++ CPA++ ++D +VP +A FI+ H+ + +L +P+ H Sbjct: 172 QLMERVKT--DLHKITCPAILFCSDEDHVVPPDNAPFIYDHIASADKKLVRLPDSYHVAT 229 Query: 276 L 276 L Sbjct: 230 L 230 >3P2M-A nrPDB Length = 330 Score = 78.3 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 44/318 (13%), Positives = 87/318 (27%), Gaps = 58/318 (18%) Query: 23 GIHVPRAGPAAAFGTSVTSAKV-----------------------AVNGVQLHYQQT--- 56 G H+ G ++ ++ V VQ Sbjct: 18 GSHMASMTGGQQMGRVLSDDELTGLDEFALLAENAEQAGVNGPLPEVERVQAGAISALRW 77 Query: 57 -GEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSR-PPDRDFPADFF 114 G + L G + D + +A D G+GHS D ++ Sbjct: 78 GGSAPRVIFLHGGGQNAHTWD-----TVIVGLGEPALAVDLPGHGHSAWREDGNYSPQLN 132 Query: 115 ERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSM 174 +++ L ++G S GG+TA+ AA P + ++V+ + Sbjct: 133 SET---LAPVLRELAPGAEFVVGMSLGGLTAIRLAAMAPDLVGELVLVDVTPSALQRHAE 189 Query: 175 IYE----------GIRDVSKWSERTRKPLEALYGYDYFART-----------CEKWVDGI 213 + G R+ + + A D + WV Sbjct: 190 LTAEQRGTVALMHGEREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRY 249 Query: 214 RQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSR-LHLMPEGKH 272 + D + + P +V G V +H+ R +H++ + H Sbjct: 250 DAIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRGVHIVEKSGH 309 Query: 273 NLHLRFADEFNKLAEDFL 290 ++ ++ L Sbjct: 310 SVQSDQPRALIEIVRGVL 327 >2EDA-A nrPDB Length = 310 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 30/179 (16%), Positives = 62/179 (34%), Gaps = 16/179 (8%) Query: 48 GVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQL-KNLNKKLFTVVAWDPRGYGHSRPP- 105 G++ HY G D + L + ++ + V+A D G+G S P Sbjct: 33 GLRAHYLDEGNSDAEDVFLCLHGEPTWSYLYRKMIPVFAESGARVIAPDFFGFGKSDKPV 92 Query: 106 -DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA 164 + D+ +F + L++ L + ++L+ GG L PS +++I A Sbjct: 93 DEEDYTFEFHRNF---LLALIERLDLRNITLVVQDWGGFLGLTLPMADPSRFKRLIIMNA 149 Query: 165 -----NAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKH 218 + + + + W P + D F ++W + + + Sbjct: 150 CLMTDPVTQPAFSAFVTQPADGFTAWKYDLVTPSDL--RLDQF---MKRWAPTLTEAEA 203 >1R1D-A nrPDB Length = 247 Score = 75.2 bits (183), Expect = 3e-14, Method: Composition-based stats. Identities = 49/237 (20%), Positives = 94/237 (39%), Gaps = 10/237 (4%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERD 117 G+ AVLLL G G D + L K +T A +G+G D + +D Sbjct: 14 AGERAVLLLHGFTG-NSADVRMLGRFLESKGYTCHAPIYKGHGVPPEELVHTGPDDWWQD 72 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE 177 + +K ++K+++ G S GG+ +L P I +V A Y+ E++M Sbjct: 73 VMNGYQFLKNKGYEKIAVAGLSLGGVFSLKLGYTVP--IEGIVTMCAPMYIKSEETMYEG 130 Query: 178 GIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL 237 + ++ +R K E + R + + ++ + L R L V P Sbjct: 131 VLEYAREYKKREGKSEEQIE--QEMERFKQTPMKTLKALQELIA--DVRAHLDLVYAPTF 186 Query: 238 IVHGEKDPLVPRFHADFIHKHV--KGSRLHLMPEGKHNLHL-RFADEFNKLAEDFLQ 291 +V D ++ A+ I+ + ++ + H + L + D+ ++ FL+ Sbjct: 187 VVQARHDEMINPDSANIIYNEIESPVKQIKWYEQSGHVITLDQEKDQLHEDIYAFLE 243 >3JWE-A nrPDB Length = 320 Score = 74.0 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 50/285 (17%), Positives = 87/285 (30%), Gaps = 25/285 (8%) Query: 22 PGIHVPRAGPAAAFGTSVTSAKVAVNGVQL---HYQQTGEGDHAVLLLPGMLGSGETDFG 78 P PR P + V +G L +++ TG + + G + Sbjct: 19 PEESSPRRTP-QSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSG-RYE 76 Query: 79 PQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKK----VS 134 + L V A D G+G S F +D + + +++ V Sbjct: 77 ELARMLMGLDLLVFAHDHVGHGQSE--GERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVF 134 Query: 135 LLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRD------VSKWSER 188 LLG S GG A++ AA+ P + MV+ E + ++ + + S Sbjct: 135 LLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLG 194 Query: 189 TRKPLEALYGYDYFARTCEKWVDGIRQFKH------LPDGNICRHLLPRVQCPALIVHGE 242 + K L + LP++ P L++ G Sbjct: 195 PIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGS 254 Query: 243 KDPLVPRFHADFIHKHVK--GSRLHLMPEGKHNLHLRFADEFNKL 285 D L A + + K L + H LH + N + Sbjct: 255 ADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSV 299 >3C5W-P nrPDB Length = 310 Score = 72.5 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 49/299 (16%), Positives = 99/299 (33%), Gaps = 39/299 (13%) Query: 23 GIHVPRAGPA--AAFGTSVTSAKVAVNGVQLHYQQTGEG-DHAVLLLPGMLGSGETDFGP 79 G H+ P + + S+ +V + ++ G + VLLL G + Sbjct: 1 GSHMRDFSPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAV 60 Query: 80 QLKNLNKK-LFTVVAWDPRGYGHSR-PPDRDFPADFFERDAKDAVDLMKALKFKKVSLLG 137 + + +VA D R +G ++ D A+ +D + V+ M + L+G Sbjct: 61 FTAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIG 120 Query: 138 WSDGGITALIAAAK--YPSYIHKMVI-------WGANAYVTDEDSMIYEGIRDVSKWSE- 187 + GG A+ A+ PS + +I A + + + + + E Sbjct: 121 HAMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEW 180 Query: 188 -------RTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRV--QCPA-- 236 R + + + I K + L + CP Sbjct: 181 SVKSGQIRNLESARVSMVGQVKQCEGKPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPK 240 Query: 237 -LIVHG----EKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 L++ G +KD + + F ++ ++P+ H +H D+ + FL Sbjct: 241 LLLLAGVDRLDKDLTIGQMQGKF--------QMQVLPQCGHAVHEDAPDKVAEAVATFL 291 >3FCY-A nrPDB Length = 346 Score = 71.3 bits (173), Expect = 4e-13, Method: Composition-based stats. Identities = 58/301 (19%), Positives = 102/301 (33%), Gaps = 47/301 (15%) Query: 17 LSALKPGIHVPRAGPAAAFGTSVTSAKVAVNGVQLH---YQQTGEGDHAVLLLPGMLGSG 73 + ++ P I + + +F V G ++H + EG H L+ S Sbjct: 61 MRSVDPKIELKESSFQVSFAECYDLYFTGVRGARIHAKYIKPKTEGKHPALIRFHGYSSN 120 Query: 74 ETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADF--------FERDAK------ 119 D+ +L N FTVVA D RG G + + DA Sbjct: 121 SGDWNDKL-NYVAAGFTVVAMDVRGQGGQSQDVGGVTGNTLNGHIIRGLDDDADNMLFRH 179 Query: 120 ---DAVDL------MKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 D L M + +V ++G S GG +L AA P + K+V + Sbjct: 180 IFLDTAQLAGIVMNMPEVDEDRVGVMGPSQGGGLSLACAALEP-RVRKVV---SEYPFLS 235 Query: 171 EDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLP 230 + +++ + + E T DYF + F L ++L Sbjct: 236 DYKRVWDLDLAKNAYQEIT----------DYFRLFDPRHERENEVFTKL-GYIDVKNLAK 284 Query: 231 RVQCPALIVHGEKDPLVPRFHADFIHKHVKGSR-LHLMPEGKHNLHLRFADEFNKLAEDF 289 R++ L+ G D + P + +++ + + + P+ H F LA F Sbjct: 285 RIKGDVLMCVGLMDQVCPPSTVFAAYNNIQSKKDIKVYPDYGHEPMR----GFGDLAMQF 340 Query: 290 L 290 + Sbjct: 341 M 341 >3A2L-A nrPDB Length = 309 Score = 68.7 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 45/288 (15%), Positives = 78/288 (27%), Gaps = 45/288 (15%) Query: 42 AKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 + V G + Y++TG D V+L + + + L + +A D G+G Sbjct: 10 RRAPVLGSSMAYRETGAQDAPVVLFLHGNPTSSHIW-RNILPLVSPVAHCIAPDLIGFGQ 68 Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161 S PD + R ++ L+ G A AA+ P ++ + Sbjct: 69 SGKPDIAYRFFDHVRYLDAF---IEQRGVTSAYLVAQDWGTALAFHLAARRPDFVRGLAF 125 Query: 162 WG---ANAYVTDEDSMIYEGIRDVS----------KWSERTRKPLEALYGYDYFARTCEK 208 D E R V +E + + ++ Sbjct: 126 MEFIRPMPTWQDFHQDHAEAARAVFRKFRTPGEGEAMILEANAFVERVLPGGIVRKLGDE 185 Query: 209 WVDGIRQFKHLPDGNICRHLLP--------------------------RVQCPALIVHGE 242 + R P R +L P L+ GE Sbjct: 186 EMAPYRTP--FPTPESRRPVLAFPRELPIAGEPADVYEALQSAHAALAASSYPKLLFTGE 243 Query: 243 KDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFL 290 LV A+ + L + G H L AD + ++ Sbjct: 244 PGALVSPEFAERFAASLTRCALIRLGAGLHYLQEDHADAIGRSVAGWI 291 >6EIC-C nrPDB Length = 279 Score = 67.9 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 44/266 (16%), Positives = 79/266 (29%), Gaps = 28/266 (10%) Query: 35 FGTSVTSA-KVAVNGVQLHYQQTGE--GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTV 91 T+ T + V++ Y AV++L LG + + L Sbjct: 1 MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDHVAQRLGAAGLVT 60 Query: 92 VAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVS-----LLGWSDGGITAL 146 A D RG+G S + D D + + ++ +LG S GG Sbjct: 61 YALDHRGHGRSG--GKRVLVRDISEYTADF-DTLVGIATREYPGCKRIVLGHSMGGGIVF 117 Query: 147 IAAAKYPSYIHKMVIWGANAYVTDEDSMIYE-------------GIRDVSKWSERTRKPL 193 + P MV+ D S + ++++ + + Sbjct: 118 AYGVERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEV 177 Query: 194 EALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHAD 253 Y D R + + R P + P L++HG D L+P + Sbjct: 178 VQAYNTDPLVHHGRVPAGIGRALLQVGETMPRR--APALTAPLLVLHGTDDRLIPIEGSR 235 Query: 254 FIHKHV--KGSRLHLMPEGKHNLHLR 277 + + V +L P H + Sbjct: 236 RLVECVGSADVQLKEYPGLYHEVFNE 261 >5HK8-A nrPDB Length = 298 Score = 67.1 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 50/293 (17%), Positives = 87/293 (29%), Gaps = 37/293 (12%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G + G + G + G + Sbjct: 18 GSHMASMTGGQQMGRGSEF----MGG------EGGAEPVIHFVFVHGASHGAWCWYKLTT 67 Query: 83 NLNKKLFTVVAWDPRGYGHSR-PPDRDFPADFFERDA-KDAVDLMKALKFKKVSLLGWSD 140 L+ F + D G G S + F +D + R DL KV L+G S Sbjct: 68 LLDAAGFKSTSVDLTGAGISLIDSNIVFDSDQYNRPLFSLLSDLPPH---HKVILVGHSI 124 Query: 141 GGITALIAAAKYPSYIHKMV-----IWGANAYVTDEDSMIYEGIRDVSK--WSERTRKPL 193 GG + A K+ I + + + + S I+ G D+ + + E T KP Sbjct: 125 GGGSVTEALCKFTDKISMAIYLAASMVQPGSIPSPHLSNIHVGEEDIWEYTYGEGTDKPP 184 Query: 194 EALYGYDYFAR------------TCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHG 241 + F R T + + D + + P + + Sbjct: 185 TGVLMKPEFIRHYYYSQSPLEDVTLSSKLLRPAPMRAFQDLDKLPPNPEAEKVPRVYIKT 244 Query: 242 EKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAED---FLQ 291 KD L D + ++ S+L+++ + H+ FLQ Sbjct: 245 AKDNLFDSVRQDLLVENWPPSQLYVLEDSDHSAFFSVPTTLFAYLLRAVSFLQ 297 >4GDM-A nrPDB Length = 268 Score = 66.3 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 38/256 (14%), Positives = 79/256 (30%), Gaps = 33/256 (12%) Query: 56 TGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFE 115 G+ L+ ++ + ++ + D G+G S D F+ Sbjct: 25 HGKPGLPWLVFLHGFSGDCHEWQEVGEAFAD--YSRLYVDLPGHGGSAA----ISVDGFD 78 Query: 116 RDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMI 175 + + L+G+S GG A++AA + + + +++ G + + + + Sbjct: 79 DVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRA 138 Query: 176 YEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWV--DGIRQFKHLPDGNICRHLLPRVQ 233 D +W +R D++ + + D R+ L N L ++ Sbjct: 139 ERQRSDR-QWVQRFLTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLE 197 Query: 234 CPALIV------------------HGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLH 275 +L V GE+D A+ H++P HN H Sbjct: 198 ATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAAD------CHVIPRAGHNAH 251 Query: 276 LRFADEFNKLAEDFLQ 291 L+ Sbjct: 252 RENPAGVIASLAQILR 267 >1R3D-A nrPDB Length = 264 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 49/267 (18%), Positives = 95/267 (35%), Gaps = 37/267 (13%) Query: 50 QLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF 109 QLH+ + V+L+ G+LGSG D+ P L +L + + D G+G P+R Sbjct: 6 QLHFAKPTARTPLVVLVHGLLGSG-ADWQPVLSHLARTQCAALTLDLPGHG--TNPERH- 61 Query: 110 PADFFERDAKDAVDLMKALKFKKVS--LLGWSDGGITALI-AAAKYPSY--IHKMVIWGA 164 D F + ++A +V L+G+S GG + A S + +I G Sbjct: 62 -CDNFAEAVEMIEQTVQAHVTSEVPVILVGYSLGGRLIMHGLAQGAFSRLNLRGAIIEGG 120 Query: 165 NAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQ--------- 215 + + + + D +W++R + D++ + ++ ++ Sbjct: 121 HFGLQENEEKAARWQHD-QQWAQRFSQQPIEHVLSDWYQQAVFSSLNHEQRQTLIAQRSA 179 Query: 216 -----------FKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRL 264 L L ++ P V GE+D + + S Sbjct: 180 NLGSSVAHMLLATSLAKQPYLLPALQALKLPIHYVCGEQDSKF-----QQLAESSGLSYS 234 Query: 265 HLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + + HN+H F K+ + + Sbjct: 235 QV-AQAGHNVHHEQPQAFAKIVQAMIH 260 >1IMJ-A nrPDB Length = 210 Score = 63.6 bits (153), Expect = 8e-11, Method: Composition-based stats. Identities = 46/253 (18%), Positives = 77/253 (30%), Gaps = 62/253 (24%) Query: 44 VAVNGVQLHYQQT--GEGDH---AVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG 98 + V G L +++ G G +LL S L L + + VA D G Sbjct: 12 IQVQGQALFFREALPGSGQARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPG 71 Query: 99 YGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHK 158 GHS+ P ++ AL+ ++ S G+ +L S + Sbjct: 72 LGHSKEAAAPAPIGELAP-GSFLAAVVDALELGPPVVISPSLSGMYSLPFLTAPGSQLPG 130 Query: 159 MVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKH 218 V + + I + S +T Sbjct: 131 FVPV---------APICTDKINAANYASVKT----------------------------- 152 Query: 219 LPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRF 278 PALIV+G++DP + K + R+ +M H +L Sbjct: 153 ----------------PALIVYGDQDP--MGQTSFEHLKQLPNHRVLIMKGAGHPCYLDK 194 Query: 279 ADEFNKLAEDFLQ 291 +E++ DFLQ Sbjct: 195 PEEWHTGLLDFLQ 207 >2O2H-A nrPDB Length = 300 Score = 60.9 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 39/286 (13%), Positives = 79/286 (27%), Gaps = 42/286 (14%) Query: 42 AKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGET-DFGPQLKNLNKKLFTVVAWDPRGYG 100 + + G ++ Y G+GD V S + P L+ L +VA D G G Sbjct: 13 KYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLG----RLVACDLIGMG 68 Query: 101 HSRPPDRDFPADF-FERDAKDAVDLMKALKF-KKVSLLGWSDGGITALIAAAKYPSYIHK 158 S P + + L AL V L+ G A ++ + Sbjct: 69 ASDKLSPSGPDRYSYGEQRDFLFALWDALDLGDHVVLVLHDWGSALGFDWANQHRDRVQG 128 Query: 159 MVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPL--------EALYGYDYFARTCEKWV 210 + A + +P+ E + + ++ + Sbjct: 129 IAFMEAIVTPMTWADWPPAVRGVFQGFRSPQGEPMALEHNIFVERVLPGAILRQLSDEEM 188 Query: 211 DGIRQ-------------------------FKHLPDGNICRHLLPRVQCPALIVHGEKDP 245 + R+ + + N R L P L ++ E Sbjct: 189 NHYRRPFVNGGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGA 248 Query: 246 LVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 ++ D++ + + + G H + +E F++ Sbjct: 249 IITGRIRDYVRSWPNQTEITV--PGVHFVQEDSPEEIGAAIAQFVR 292 >6COB-A nrPDB Length = 260 Score = 60.2 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 40/242 (16%), Positives = 85/242 (35%), Gaps = 25/242 (10%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVD 123 +L G + L V A + G P + + + +K ++ Sbjct: 7 FVLVHNACHGAWIWYKLKPLLESAGHRVTAVELAASGIDPRPIQ--AVETVDEYSKPLIE 64 Query: 124 LMKAL-KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA--------NAYVTDEDSM 174 +K+L + ++V L+G+S GGI +AA +P+ I +V A ++V D+ Sbjct: 65 TLKSLPENEEVILVGFSFGGINIALAADIFPAKIKVLVFLNAFLPDTTHVPSHVLDKLME 124 Query: 175 IYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDG------IRQFKHLPDGNICRHL 228 ++ G D S TR +L + + + + H L Sbjct: 125 MFGGWGDTEFSSHETRNGTMSLLKMGPKFMKARLYQNCPIEDYELAKMLHRQGSLFTEDL 184 Query: 229 LPRVQ--------CPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFAD 280 + + + V +D ++P ++ + S+++ + G H + L Sbjct: 185 SKKEKFSEEGYGSVQRVYVMSSEDKIIPCDFIRWMIDNFNVSKVYEIDGGDHMVMLSKPQ 244 Query: 281 EF 282 + Sbjct: 245 KL 246 >2WFL-A nrPDB Length = 264 Score = 57.5 bits (137), Expect = 7e-09, Method: Composition-based stats. Identities = 46/258 (17%), Positives = 79/258 (30%), Gaps = 29/258 (11%) Query: 56 TGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFE 115 + H VL+ G LG+ + L V A D G + P R F Sbjct: 7 AKQQKHFVLVHGGCLGA--WIWYKLKPLLESAGHKVTAVDLSAAGIN--PRRLDEIHTFR 62 Query: 116 RDAKDAVDLMKALKFK-KVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSM 174 ++ +++M ++ KV LLG S GG++ +A YP I V A + Sbjct: 63 DYSEPLMEVMASIPPDEKVVLLGHSFGGMSLGLAMETYPEKISVAVFMSAMMPDPNHSLT 122 Query: 175 IYEGIR------------DVSKWSERTRKPLEALYGYDYFARTC--EKWVDGIRQFKHLP 220 S + + + G + A V+ + K L Sbjct: 123 YPFEKYNEKCPADMMLDSQFSTYGNPENPGMSMILGPQFMALKMFQNCSVEDLELAKMLT 182 Query: 221 D-GNICRHLLPRVQ---------CPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEG 270 G++ L + + + +D P + + V ++ + E Sbjct: 183 RPGSLFFQDLAKAKKFSTERYGSVKRAYIFCNEDKSFPVEFQKWFVESVGADKVKEIKEA 242 Query: 271 KHNLHLRFADEFNKLAED 288 H L E K D Sbjct: 243 DHMGMLSQPREVCKCLLD 260 >3FLA-A nrPDB Length = 267 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 42/227 (18%), Positives = 68/227 (29%), Gaps = 12/227 (5%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG-YGHSRPPDRDFPADFFER 116 D L+ G F L V+A G P P D Sbjct: 16 APDARARLVCLPHAGGSASFFFPLAKALAPAVEVLAVQYPGRQDRRHEP----PVDSIGG 71 Query: 117 DAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIY 176 +++++ + ++L G S G I A + P + + Sbjct: 72 LTNRLLEVLRPFGDRPLALFGHSMGAIIGYELALRMPEAGLPAPVHLFASGRRAPSRYRD 131 Query: 177 EGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVD-GIRQFKHLPDGNICRHLLP--RVQ 233 + +R S ER L L G D + + + + P RV Sbjct: 132 DDVRGAS--DERLVAELRKLGGSDAAMLADPELLAMVLPAIRSDYRAVETYRHEPGRRVD 189 Query: 234 CPALIVHGEKDPLVPRFHADFIHKHVKG-SRLHLMPEGKHNLHLRFA 279 CP + G+ DP V A +H G + L ++P H + A Sbjct: 190 CPVTVFTGDHDPRVSVGEARAWEEHTTGPADLRVLPG-GHFFLVDQA 235 >3IBT-A nrPDB Length = 264 Score = 56.3 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 41/274 (14%), Positives = 77/274 (28%), Gaps = 36/274 (13%) Query: 42 AKVAVNGVQLHYQQTGEGD-HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 + VNG + Y ++G+ + LL G + L L + F V+ D RG+ Sbjct: 2 QSLNVNGTLMTYSESGDPHAPTLFLLSGWCQ--DHRLFKNLAPLLARDFHVICPDWRGHD 59 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIA-----AAKYPSY 155 + DF + A+D + + A + ++ S G + AA+ P Sbjct: 60 AKQTDSGDF---DSQTLAQDLLAFIDAKGIRDFQMVSTSHGCWVNIDVCEQLGAARLPKT 116 Query: 156 IHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYF------------- 202 I + + + + V+ + E D Sbjct: 117 IIIDWLLQPHPGFWQQLAEGQHPTEYVAGRQSFFDEWAETTDNADVLNHLRNEMPWFHGE 176 Query: 203 --ARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVK 260 R C + R + D P + + + + + Sbjct: 177 MWQRACREIEANYRTWGSPLDRMDSLPQKPE-------ICHIYSQPLSQDYRQLQLEFAA 229 Query: 261 GS---RLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 G +P H L + +FLQ Sbjct: 230 GHSWFHPRHIPGRTHFPSLENPVAVAQAIREFLQ 263 >4ZWN-A nrPDB Length = 334 Score = 55.2 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 51/285 (17%), Positives = 94/285 (32%), Gaps = 40/285 (14%) Query: 42 AKVAVNGVQLHYQQT----GEGD--HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWD 95 +G + Y G + VLL+ G + F + +L+ + +D Sbjct: 37 QYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQF-RLMDHLSLNGYESFTFD 95 Query: 96 PRGY-----GHSRPPDRDFPA-DFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAA 149 RG G S+ ++ + E + + KA + + G S GG L A Sbjct: 96 QRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIP-LFMWGHSMGGGICLNYA 154 Query: 150 --AKYPSYIHKMVIWGAN--AYVTDEDSMIYEGIRD-VSKWSERTR-------KPLEALY 197 K+ + I + G + + + I ++K+S R R K + + Sbjct: 155 CQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFSPRVRIDTGLDLKGITSDK 214 Query: 198 GYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPR-----------VQCPALIVHGEKDPL 246 Y F + V F+ + D L + P +I+HG+ D + Sbjct: 215 AYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTI 274 Query: 247 VPRFHADFIHKHVKGS--RLHLMPEGKH-NLHLRFADEFNKLAED 288 ++ + + L L P +H L FN + D Sbjct: 275 NDPKGSEKFIRDCPSADKELKLYPGARHSIFSLETDKVFNTVFND 319 >3DYV-A nrPDB Length = 251 Score = 55.2 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 46/245 (18%), Positives = 75/245 (30%), Gaps = 20/245 (8%) Query: 53 YQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPA- 111 ++ G VLL + +F + L + + V G+G P D Sbjct: 16 FEYEGTDTGVVLLHAYTGSPNDMNFMA--RALQRSGYGVYVPLFSGHGTVEPLDILTKGN 73 Query: 112 -DFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 D + ++ AV M A K+ KV + G S GGI A+ A P V Sbjct: 74 PDIWWAESSAAVAHMTA-KYAKVFVFGLSLGGIFAMKALETLPGITAGGVFSSPILPGKH 132 Query: 171 EDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLP 230 + K++E + + I QF + L Sbjct: 133 HLVPGF------LKYAEYMNRLAGKSDESTQILAYLPGQLAAIDQFATTVAAD-----LN 181 Query: 231 RVQCPALIVHGEKDPLVP---RFHADFIHKHVKGSRLHLMPEGKHNLHLRFA-DEFNKLA 286 V+ P I +D LV + + H + KH + + A + Sbjct: 182 LVKQPTFIGQAGQDELVDGRLAYQLRDALINAARVDFHWYDDAKHVITVNSAHHALEEDV 241 Query: 287 EDFLQ 291 F+Q Sbjct: 242 IAFMQ 246 >2RON-A nrPDB Length = 242 Score = 54.8 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 36/234 (15%), Positives = 71/234 (30%), Gaps = 21/234 (8%) Query: 65 LLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDL 124 L+ G + L + ++A +P G+G + + + E Sbjct: 16 LICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTN----QTSAIEDLEELTDLYKQE 71 Query: 125 MKALKFKK-VSLLGWSDGGITALIAAAK------YPSYIHKMVIWGANAYVTDEDSMIYE 177 + L+ + L G S GG+ A K +P + I + + + Sbjct: 72 LN-LRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAIQPPHIQRKKVSHLPDD 130 Query: 178 GIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL 237 + + P E + + + + R + + L ++Q P Sbjct: 131 QF--LDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYD-----LAQIQSPVH 183 Query: 238 IVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + +G D R A+ K K H +G H L +E + L Sbjct: 184 VFNGLDDKKCIRD-AEGWKKWAKDITFHQF-DGGHMFLLSQTEEVAERIFAILN 235 >1SCK-A nrPDB Length = 257 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 43/248 (17%), Positives = 84/248 (33%), Gaps = 29/248 (11%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVD 123 +L + G + L V A D G P + F+ ++ + Sbjct: 6 FVLIHTICHGAWIWHKLKPLLEALGHKVTALDLAASG--VDPRQIEEIGSFDEYSEPLLT 63 Query: 124 LMKALKF-KKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA--------NAYVTDEDSM 174 ++AL +KV L+G S GG+ IAA KY I V + +YV D+ Sbjct: 64 FLEALPPGEKVILVGESCGGLNIAIAADKYCEKIAAAVFHNSVLPDTEHCPSYVVDKLME 123 Query: 175 IYEGIRDVSKWSERT---------------RKPLEALYGY-DYFARTCEKWVDGIRQFKH 218 ++ +D + ++ R+ L L G +Y + Q Sbjct: 124 VFPDWKDTTYFTYTKDGKEITGLKLGFTLLRENLYTLCGPEEYELAKMLTRKGSLFQNIL 183 Query: 219 LPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRF 278 + ++ + V ++D + + ++ K +++ + G H L L Sbjct: 184 AKRPFFTKEGYGSIKK--IYVWTDQDEIFLPEFQLWQIENYKPDKVYKVEGGDHLLQLTK 241 Query: 279 ADEFNKLA 286 E ++ Sbjct: 242 TKEIAEIL 249 >2PSJ-A nrPDB Length = 319 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 36/276 (13%), Positives = 82/276 (29%), Gaps = 43/276 (15%) Query: 52 HYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPP-DRDFP 110 +Y ++AV+ L G + + + + + + D G G S + + Sbjct: 36 YYDSEKHAENAVIFLHG--NATSSYLWRHVVPHIEPVARCIIPDLIGMGKSGKSGNGSYR 93 Query: 111 ADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 + +L+ KK+ +G G A A ++ I +V + V + Sbjct: 94 LLDHYKYLTAWFELLNL--PKKIIFVGHDWGAALAFHYAYEHQDRIKAIVHMESVVDVIE 151 Query: 171 EDSMIYEGIRDVSKWSERTRKPL--------EALYGYDYFARTCEK----WVDGIRQFKH 218 + D++ + + E + + + +++ ++ Sbjct: 152 SWDEWPDIEEDIALIKSEEGEKMVLENNFFVETVLPSKIMRKLEPEEFAAYLEPFKEKGE 211 Query: 219 LPDGNICRH-LLPRVQ----------------------CPALIVHGEKDPLVPRFHADFI 255 + + +P V+ P L + E DP Sbjct: 212 VRRPTLSWPREIPLVKGGKPDVVQIVRNYNAYLRASDDLPKLFI--ESDPGFFSNAIVEG 269 Query: 256 HKHVKGSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 K + + +G H L DE K + F++ Sbjct: 270 AKKFPNTEF-VKVKGLHFLQEDAPDEMGKYIKSFVE 304 >2Y6V-A nrPDB Length = 398 Score = 52.1 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 48/320 (15%), Positives = 100/320 (31%), Gaps = 69/320 (21%) Query: 30 GPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDH----------AVLLLPGMLGSG--ETDF 77 +A++ + S A + ++L Y + ++ L G S + Sbjct: 12 TCSASWPRAPQSTLCATDRLELTYDVYTSAERQRRSRTATRLNLVFLHGSGMSKVVWEYY 71 Query: 78 GPQLKNLNKKLF----TVVAWDPRGYGHSRPPDRDFPADFFERD--AKDAVDLMK-ALKF 130 P+L + + V+ D +G S +R F A+D + + L Sbjct: 72 LPRLVAADAEGNYAIDKVLLIDQVNHGDSAVRNRGRLGTNFNWIDGARDVLKIATCELGS 131 Query: 131 KKVS-----LLGWSDGGITALIAAAKYPSYIHKMVIWGAN-----------AYVTDEDSM 174 ++G S GG AL P+ H +++ + + Sbjct: 132 IDSHPALNVVIGHSMGGFQALACDVLQPNLFHLLILIEPVVITRKAIGAGRPGLPPDSPQ 191 Query: 175 IYEGIRDVSKWS-----ERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLP------DGN 223 I E + + + + ++ + +F + + I F+ DG Sbjct: 192 IPENLYNSLRLKTCDHFANESEYVKYMRNGSFFTNAHSQILQNIIDFERTKASGDDEDGG 251 Query: 224 ICRHLLPRVQ-----------CPALI------------VHGEKDPLVPRFHADFIHKHVK 260 R + + Q P LI + G + P + F+ K ++ Sbjct: 252 PVRTKMEQAQNLLCYMNMQTFAPFLISNVKFVRKRTIHIVGARSNWCPPQNQLFLQKTLQ 311 Query: 261 GSRLHLMPEGKHNLHLRFAD 280 L ++P G H +++ D Sbjct: 312 NYHLDVIPGGSHLVNVEAPD 331 >2WJ4-A nrPDB Length = 276 Score = 51.7 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 52/133 (39%), Gaps = 11/133 (8%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH--SRPPDRDFPADFFERDA 118 A+LLLPG + ++ L F V+ + RG+G S PD + Sbjct: 28 PAILLLPGWC-HDHRVYKYLIQEL-DADFRVIVPNWRGHGLSPSEVPDFGYQ-----EQV 80 Query: 119 KDAVDLMKALKFKKVSLLGWSDGGITALIAAAKY-PSYIHKMVIWGANAYVTDED-SMIY 176 KDA++++ L + + S GG + + P + +I + D + Sbjct: 81 KDALEILDQLGVETFLPVSHSHGGWVLVELLEQAGPERAPRGIIMDWLMWAPKPDFAKSL 140 Query: 177 EGIRDVSKWSERT 189 ++D +W E T Sbjct: 141 TLLKDPERWREGT 153 >6FKX-A nrPDB Length = 324 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 53/285 (18%), Positives = 90/285 (31%), Gaps = 45/285 (15%) Query: 17 LSALKPGIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQ----TGEGDHAVLLLPGMLGS 72 L+A+ + + A GV++H + H LL Sbjct: 39 LAAVPADVVIEPAEFTTPLARCSHLWFTGTGGVRVHAKLLRPVAPVEPHPALLQFHGYTG 98 Query: 73 GETDFGPQLKNLNKKLFTVVAWDPRGY-GHS--RPPDRDFPADFF-----ERDAKDAVDL 124 D+ +L +TV A D RG G S P ++ + + DA D + L Sbjct: 99 NSGDWSSRLHY-VALGYTVAALDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAADNLAL 157 Query: 125 ----------------MKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYV 168 M + +V+ G+S GG L AA P ++ + Sbjct: 158 RHLFLDTARLAQIVLAMDDVDPDRVAATGYSQGGGLTLACAALEP----RIRLAAPVYPF 213 Query: 169 TDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHL 228 + +E + ++E T YF + + F L +HL Sbjct: 214 LCDFRRAWEMDLEKGPYNEITT----------YFRARDPRHLREEEIFSRL-GYVDVQHL 262 Query: 229 LPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSR-LHLMPEGKH 272 PRV+ L+ D + P + + G + L P+ H Sbjct: 263 APRVRAEVLMTVSLADKICPPSTQFAAYNKLGGPKDYRLYPDFAH 307 >3KSR-A nrPDB Length = 290 Score = 50.9 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 37/240 (15%), Positives = 69/240 (28%), Gaps = 35/240 (14%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERD 117 G VL + G GS + + +D RG+ + D Sbjct: 26 TGMPGVLFVHGWGGSQHHSLVR-AREAVGLGCICMTFDLRGHEGYASMRQSVTRAQNLDD 84 Query: 118 AKDAVDLMKALKFKKVS---LLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSM 174 K A D + +L + ++G S GG + + + P + + + Y Sbjct: 85 IKAAYDQLASLPYVDAHSIAVVGLSYGGYLSALLTRERP--VEWLALRSPALYKDAH--- 139 Query: 175 IYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQC 234 W + +D R+ P N+ + + Sbjct: 140 ----------WDQP-----------KVSLNADPDLMD-YRRRALAPGDNLALAACAQYKG 177 Query: 235 PALIVHGEKDPLVPRFHADFIHKHVKGSR---LHLMPEGKHNLHL-RFADEFNKLAEDFL 290 L+V E D +VP +R ++ H L + E+ + D+L Sbjct: 178 DVLLVEAENDVIVPHPVMRNYADAFTNARSLTSRVIAGADHALSVKEHQQEYTRALIDWL 237 >1Y7H-A nrPDB Length = 268 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 41/265 (15%), Positives = 76/265 (28%), Gaps = 39/265 (14%) Query: 57 GEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFER 116 EG H VL+ G + L V A D G + Sbjct: 2 KEGKHFVLVHG--ACHGGWSWYKLKPLLEAAGHKVTALDLAASG--TDLRKIEELRTLYD 57 Query: 117 DAKDAVDLMKALKFK-KVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMI 175 ++LM++L KV L+G S GG+ +A KYP I+ V A + +S Sbjct: 58 YTLPLMELMESLSADEKVILVGHSLGGMNLGLAMEKYPQKIYAAVFLAAFMPDSVHNSSF 117 Query: 176 YEGIRDVSKWSERTRK--PLEALY--------GYDYFARTCEKWVDGIRQFKHLPDGNIC 225 + +++ERT L+ + + + Q D + Sbjct: 118 V-----LEQYNERTPAENWLDTQFLPYGSPEEPLTSMFFGPKFLAHKLYQLCSPEDLALA 172 Query: 226 RHL----------LPRVQ---------CPALIVHGEKDPLVPRFHADFIHKHVKGSRLHL 266 L L + + + + +D +P + ++ + Sbjct: 173 SSLVRPSSLFMEDLSKAKYFTDERFGSVKRVYIVCTEDKGIPEEFQRWQIDNIGVTEAIE 232 Query: 267 MPEGKHNLHLRFADEFNKLAEDFLQ 291 + H L + + Sbjct: 233 IKGADHMAMLCEPQKLCASLLEIAH 257 >5L8S-A nrPDB Length = 604 Score = 49.0 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 43/239 (17%), Positives = 85/239 (35%), Gaps = 37/239 (15%) Query: 66 LPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG-YGHSRPPDRDFPADFFERDAKDAVDL 124 G + F + + +T+ A + RG G+ + D+ E D + Sbjct: 378 HGGPQSAERKMFRSMFQCFINRGYTIFAPNFRGSTGYGSAFTKLVELDWGEGPRLDCIAG 437 Query: 125 MKAL------KFKKVSLLGWSDGGITALIAAAKYPSYIHKMV-IWGANAYVTDEDSMIYE 177 ++ L K+ L+G S GG AL+ ++ Y +V I+G + T +S+ Sbjct: 438 IEWLFESGFTDRNKLFLVGGSYGGYMALLLHGRHSDYFRAVVDIFGPSDLFTFINSVPPH 497 Query: 178 GIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL 237 + +W + E + ++DG+ + P L Sbjct: 498 WKPIMERWLGDPERDKERFIK-----DSPVTYLDGMVK-------------------PML 533 Query: 238 IVHGEKDPLVPRFHADFIHKHVK----GSRLHLMPEGKHNLHLRFAD-EFNKLAEDFLQ 291 ++ G KDP V + +D I +K ++ + H + + + L FL+ Sbjct: 534 VIQGAKDPRVVKEESDQIVAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVYSLMLAFLE 592 >3O4I-A nrPDB Length = 582 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 34/230 (14%), Positives = 71/230 (30%), Gaps = 41/230 (17%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFF-ER 116 G VL+ G + +L F VV + RG S ++ + Sbjct: 359 PGPTVVLVHGGPFAEDSDSWDTFAASLAAAGFHVVMPNYRG---STGYGEEWRLKIIGDP 415 Query: 117 DAKDAVDLMKALKFKK-------VSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVT 169 + D+ A ++ + + ++G+S GG L A P A V Sbjct: 416 CGGELEDVSAAARWARESGLASELYIMGYSYGGYMTLCALTMKPGLFK--------AGVA 467 Query: 170 DEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLL 229 + +E + ++S + R + + + H+ Sbjct: 468 GASVVDWEEMYELSDAAFR--------NFIEQLTGGSREIMRSRSPINHV---------- 509 Query: 230 PRVQCPALIVHGEKDPLVPRFHAD----FIHKHVKGSRLHLMPEGKHNLH 275 R++ P ++H + P + K H++P+ H ++ Sbjct: 510 DRIKEPLALIHPQNASRTPLKPLLRLMGELLARGKTFEAHIIPDAGHAIN 559 >6FVJ-A nrPDB Length = 261 Score = 47.5 bits (111), Expect = 7e-06, Method: Composition-based stats. Identities = 36/205 (17%), Positives = 74/205 (36%), Gaps = 16/205 (7%) Query: 55 QTGEGDHAVLLLPGMLGSGETD--FGPQLKNLNKKLFTVVAWDPRG-YGHSRPPDRDFPA 111 + + + P G+ + F + K+ +A G + S P P Sbjct: 23 DAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKR----IAVQYPGQHDRSGLP----PL 74 Query: 112 DFFERDAKDAVDLMK-ALKFKK-VSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVT 169 + A + +MK + + V+ G S GG+ A A +Y S H+++ + +A + Sbjct: 75 ESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSA-CS 133 Query: 170 DEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPD-GNICRHL 228 + Y+ ++D+S D+F E +V + + + Sbjct: 134 APGHIRYKQLQDLSDREMLDLFTRMTGMNPDFFT-DDEFFVGALPTLRAVRAIAGYSCPP 192 Query: 229 LPRVQCPALIVHGEKDPLVPRFHAD 253 ++ CP G+KD + + D Sbjct: 193 ETKLSCPIYAFIGDKDWIATQDDMD 217 >1DWO-A nrPDB Length = 262 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 35/247 (14%), Positives = 74/247 (29%), Gaps = 26/247 (10%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVD 123 +L + G + L + V A D G P + + F+ ++ + Sbjct: 10 FVLIHTICHGAWIWHKLKPALERAGHKVTALDMAASG--IDPRQIEQINSFDEYSEPLLT 67 Query: 124 LMKAL-KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIY--EGIR 180 ++ L + +KV ++G S G+ IAA +Y I V + T + + Sbjct: 68 FLEKLPQGEKVIIVGESCAGLNIAIAADRYVDKIAAGVFHNSLLPDTVHSPSYTVEKLLE 127 Query: 181 DVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLL----------- 229 W + + G + F DG + Sbjct: 128 SFPDWRDTEYFTFTNITGETITTMKLGFVLLRENLFTKCTDGEYELAKMVMRKGSLFQNV 187 Query: 230 ----PRVQ------CPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFA 279 P+ + + ++D + + + K +++ + G H L L Sbjct: 188 LAQRPKFTEKGYGSIKKVYIWTDQDKIFLPDFQRWQIANYKPDKVYQVQGGDHKLQLTKT 247 Query: 280 DEFNKLA 286 +E + Sbjct: 248 EEVAHIL 254 >1OIL-A nrPDB Length = 320 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 43/109 (39%), Gaps = 10/109 (9%) Query: 62 AVLLLPGMLGSG-----ETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFER 116 ++L+ G+ G+ + ++L ++ TV + G+ P+ + Sbjct: 10 PIILVHGLTGTDKYAGVLEYWYGIQEDLQQRGATVYVANLSGFQSDDGPNGRGE-----Q 64 Query: 117 DAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165 ++ A KV+L+G S GG+T+ AA P + + G Sbjct: 65 LLAYVKTVLAATGATKVNLVGHSQGGLTSRYVAAVAPDLVASVTTIGTP 113 >2HCU-A nrPDB Length = 213 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 34/239 (14%), Positives = 73/239 (30%), Gaps = 38/239 (15%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G G V L+ + + + Q Sbjct: 1 GSHMASMTGGQQMGRGSMEEFTIYTGT------------TVPLMNDNIDTDQ-ILPKQFL 47 Query: 83 NLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLL--GWSD 140 L D +G+G + + + + + ++++ S+L G + Sbjct: 48 KLI---------DKKGFGKYLMYEWRYLDNNYTENPDFI---FNQPEYREASILITGDNF 95 Query: 141 GGITALIAAA-KYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGY 199 G ++ AA Y K+++ G+ + + D++ +P E Sbjct: 96 GAGSSREHAAWALADYGFKVIVAGSFGDIHYNN--------DLNNGILPIIQPKEVRDKL 147 Query: 200 DYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKH 258 T E V+ Q + P G+ + + L +G D + + D I ++ Sbjct: 148 AKLKPTDEVTVNLFEQKIYSPVGDFSFDIDGEWKHKLL--NGLDDIGITLQYEDLIAQY 204 >1TAH-B nrPDB Length = 318 Score = 44.0 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 26/167 (15%), Positives = 57/167 (34%), Gaps = 12/167 (7%) Query: 62 AVLLLPGMLGSG-----ETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFER 116 V+L+ G+ G+ + +L V + G+ P+ + Sbjct: 9 PVILVHGLAGTDKFANVVDYWYGIQSDLQSHGAKVYVANLSGFQSDDGPNGRGE-----Q 63 Query: 117 DAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIY 176 ++ A KV+L+G S GG+T+ AA P + + G ++ + Sbjct: 64 LLAYVKQVLAATGATKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFADFVQ 123 Query: 177 EGIR-DVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDG 222 + ++ D + S ++G + + D + + L Sbjct: 124 DVLKTDPTGLSSTVIAAFVNVFGT-LVSSSHNTDQDALAALRTLTTA 169 >4GW3-A nrPDB Length = 307 Score = 43.2 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 38/228 (16%), Positives = 73/228 (32%), Gaps = 28/228 (12%) Query: 62 AVLLLPGMLG----SGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERD 117 ++L+ G+ G G F L + V + + + Sbjct: 26 PIVLVHGLAGFNEIVGFPYFYGIADALRQDGHQVFTASLSAFNSNEV-----RGKQLWQF 80 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE 177 + + +A KKV+ +G S G + AA YP + + + E + +Y Sbjct: 81 VQTLLQETQA---KKVNFIGHSQGPLACRYVAANYPDSVASVTSINGVNH-GSEIADLYR 136 Query: 178 GIRDVSKWSERTRKPLEALYGYDY--FARTCEKWVDGIRQFKHLPDGNICR--HLLPRV- 232 I E + + +G F+ D I + L + + P+ Sbjct: 137 RIMRKDSIPEYIVEKVLNAFGTIISTFSGHRGDPQDAIAALESLTTEQVTEFNNKYPQAL 196 Query: 233 -QCPALIVHGEKDPLVPRFH----ADFIHKHVKGSRLHLMPEGKHNLH 275 + P GE D +V H +I + G + +L+ + H Sbjct: 197 PKTP----GGEGDEIVNGVHYYCFGSYIQGLIAGEKGNLL-DPTHAAM 239 >3I2H-A nrPDB Length = 587 Score = 43.2 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 41/236 (17%), Positives = 68/236 (28%), Gaps = 38/236 (16%) Query: 47 NGVQLH---YQQTGEGDHAVLLLPGMLGS----GETDFGPQLKNLNKKLFTVVAWDPRGY 99 +GV+L Y+ +G VLL+ + + + VV D RG Sbjct: 18 DGVRLAVDLYRPDADGPVPVLLVRNPYDKFDVFAWSTQSTNWLEFVRDGYAVVIQDTRGL 77 Query: 100 GHSRPPDRDFPADFFERDAKDAVDLMKALKF--------KKVSLLGWSDGGITALIAAAK 151 S F D D L + V + G S G+T AA Sbjct: 78 FASE--------GEFVPHVDDEADAEDTLSWILEQAWCDGNVGMFGVSYLGVTQWQAAV- 128 Query: 152 YPSYIHKMVIWGANAYVTDEDSMIYEG------IRDVSKWSERTRKPLEALYGYDYFART 205 S + + + D + G + + WS + L Sbjct: 129 --SGVGGLKAIAPSMASADLYRAPWYGPGGALSVEALLGWSAKIGTGLITSRS----DAR 182 Query: 206 CEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL--IVHGEKDPLVPRFHADFIHKHV 259 E D ++ L D + P + P L ++ D +V D + + Sbjct: 183 PEDAADFVQLAAILNDVAGAASVTPLAEQPLLGRLIPWVIDQVVDHPDNDESWQSI 238 >4HXF-B nrPDB Length = 622 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 41/256 (16%), Positives = 79/256 (30%), Gaps = 47/256 (18%) Query: 40 TSAKVAVNGVQLHYQQTGEGDHA---VLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDP 96 S + ++G + + EG+ A V + G G F +++ + K + +V +P Sbjct: 357 KSIDLELDGWYIK-PEIKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNP 415 Query: 97 RGYGHSRPPDRDFPADFFERDA-KDAVDLMKAL----------KFKKVSLLGWSDGGITA 145 RG S DF ER +D D++ + +++ + G S GG Sbjct: 416 RG---SNGYSEDFALRVLERTGLEDFQDILNGIEEFLRLEPQADRERIGITGISYGGYMT 472 Query: 146 LIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFART 205 A + +Y + G+ + D Sbjct: 473 NW-ALTQSDLFKAGISENGISYWLTSYAFSDIGL------------WFDKEVIGDNPLEN 519 Query: 206 CEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLH 265 R+ L V+ P L++H +D P + + +K Sbjct: 520 EN-----YRKLSPLFYA-------KNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKE 567 Query: 266 L----MPEGKHNLHLR 277 + +G H +R Sbjct: 568 VYIAIFKKGAHGHSIR 583 >5D6O-A nrPDB Length = 349 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 40/294 (13%), Positives = 81/294 (27%), Gaps = 74/294 (25%) Query: 51 LHYQQTG---EGDHAVLLLPGMLGSGETDFGPQLKNLNKK----LFTVVAWDPRGYGHSR 103 L Y G E +L+P + Q + + +++ + G G S Sbjct: 36 LAYATAGTLNEDKSNAILIPTWYSGTHQTWFQQYIGTDHALDPSKYFIISINQIGNGLSV 95 Query: 104 PPDRDFPADF------FERDAKDAVD----LMKALKFKKVS-LLGWSDGGITALIAAAKY 152 P R D V L + ++ ++G S G ++ Sbjct: 96 SPANTADDSISMSKFPNVRIGDDVVAQDRLLRQEFGITELFAVVGGSMGAQQTYEWIVRF 155 Query: 153 PSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWS-----------------ERTRKPLEA 195 P +H+ A T D + + + + + R + L A Sbjct: 156 PDQVHRAAPIAGTAKNTPHDFIFTQTLNETVEADPGFNGGEYSSHEEVADGLRRQSHLWA 215 Query: 196 LYGYDY----------------------------FARTCEKWVDGIRQFKHLPDGNICRH 227 G+ + ++ +++H G++ RH Sbjct: 216 AMGFSTEFWKQEAWRRLGLESKESVLADFLDPLFMSMDPNTLLNNAWKWQH---GDVSRH 272 Query: 228 -------LLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPE-GKHN 273 L RV+ ++ +D P + GS L ++ + H Sbjct: 273 TGGDLAAALGRVKAKTFVMPISEDMFFPVRDCAAEQALIPGSELRVIEDIAGHL 326 >3VVL-A nrPDB Length = 394 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 54/151 (35%), Gaps = 30/151 (19%) Query: 48 GVQLHYQQTGE----GDHAVLLLPGM------------LGSGETDFGP-QLKNLNKKLFT 90 G ++ Y+ G D+AVL+L G+ G + K ++ L+ Sbjct: 48 GARIAYETFGSLNAARDNAVLVLTGLSPDAHAASRPDDPTPGWWEAMVGPGKPVDTDLWH 107 Query: 91 VVAWDPRGYGH------SRPPDRD------FPADFFERDAKDAVDLMKALKFKK-VSLLG 137 V+ + G S P FP E A A ++AL + ++G Sbjct: 108 VICVNSLGSCKGSTGPASTDPRTGEPYRLSFPELSIEDIADAAAHTVRALGISRLACVVG 167 Query: 138 WSDGGITALIAAAKYPSYIHKMVIWGANAYV 168 S GG++AL A++P + + Sbjct: 168 ASMGGMSALALLARHPELARTHISLSGAVHA 198 >5T88-A nrPDB Length = 616 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 47/261 (18%), Positives = 84/261 (32%), Gaps = 37/261 (14%) Query: 45 AVNGVQLHY-QQTGEGDHA---VLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYG 100 + +G ++HY GE D V G + F PQ+ K+ T + + RG Sbjct: 376 SKDGTKVHYFIVKGERDEKRAWVFGYGGFNIALTPMFFPQVIPFLKRGGTFIMANLRGGS 435 Query: 101 HSRPPDRDFPADFFERDA-KDAVDLMKALKFK--KVSLLGWSDGGITALIAAAKYPSYIH 157 +++ D + +++ LK + KV+ G S+GG+ + P + Sbjct: 436 EYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGGLLVSATLTQRPDVMD 495 Query: 158 KMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFK 217 + G +Y G + ++ E D K Sbjct: 496 S-ALIGYPVIDMLRFHKLYIGSVWIPEY------------------GNPEDPKDREFLLK 536 Query: 218 HLPDGNICRHLLPRVQC-PALIVHGEKDPLVPRFHAD----FIHKHVKGSRLHLMPEGKH 272 + P ++ P+ + P LI G D V HA + + L + + H Sbjct: 537 YSP----YHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGH 592 Query: 273 --NLHLRFADEFNKLAEDFLQ 291 A E L L+ Sbjct: 593 MGASPETRARELTDLLAFVLK 613 >3WYD-A nrPDB Length = 228 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 37/237 (15%), Positives = 62/237 (26%), Gaps = 78/237 (32%) Query: 61 HAVLLLPGMLGSGETDFGPQ-----LKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFE 115 V+ L GM G + F + + + V R P + E Sbjct: 38 PLVIALHGMGGDENSYFDSYQRGAFMIEAENRGYIVACP------KGRQPASMY-VGPAE 90 Query: 116 RDAKDAVDLMK---ALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDED 172 RD D + ++ + ++ + G S GG A +P + Sbjct: 91 RDVMDVIAEVRRDYKIDPDRIYMTGHSMGGYGTWSIAMNHPDVFAALAPVAGGGNP---- 146 Query: 173 SMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRV 232 G+ H Sbjct: 147 --------------------------------------LGMANIAH-------------- 154 Query: 233 QCPALIVHGEKDPLVPRFHADFIHKHVK--GSRLHL--MPEGKH--NLHLRFADEFN 283 P L+VHG+ D VP + + + K G+ + +P G H F D F+ Sbjct: 155 -IPQLVVHGDNDKTVPVERSRVMVEAAKKHGTEIKYIEIPGGDHVSVAARTFKDVFD 210 >5J7Z-A nrPDB Length = 500 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 44/178 (24%), Gaps = 33/178 (18%) Query: 23 GIHVPRAGPAAAFGTSVTS-----AKVAVNGVQLHYQQTGEGDHAVLLLPGMLG------ 71 G H+ G + +G L G G +LL G+ Sbjct: 18 GSHMASMTGGQQMGRGSAPPATPITTLQADGTHL---VDGYGRT--VLLHGVNNVDKDAP 72 Query: 72 --SGETDFGPQ-LKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKAL 128 PQ + L + F V G S E ++ AL Sbjct: 73 YLPAGETLTPQDIDILVRHGFNTVRL-----GTSFDALMPQRGQIDEAYLDRLTGVVDAL 127 Query: 129 KFKKVSLL------GWS--DGG-ITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE 177 + + +L G S GG A P + + ++ E Sbjct: 128 TARGMHVLLDNHQDGLSKAWGGNGFPEWAIESRPREWEPNPGFPLYYLMPSLNAGWDE 185 >2VAV-A nrPDB Length = 444 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 45/131 (34%), Gaps = 7/131 (5%) Query: 161 IWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLP 220 I G ++ + E + S + +K + Y A T + I + + Sbjct: 315 INGTDSGNSHRAGQPIEAVS--SYLRYQAQKFAASFDANCYIAMTLKFDTHDISRGRAGS 372 Query: 221 DGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMP-EGKHNLHLRFA 279 L + PALI+ D L + + + SRL ++ H+ + A Sbjct: 373 ----IPEALAMITQPALIICARSDGLYSFDEHVEMGRSIPNSRLCVVDTNEGHDFFVMEA 428 Query: 280 DEFNKLAEDFL 290 D+ N FL Sbjct: 429 DKVNDAVRGFL 439 Score = 40.9 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 44/217 (20%), Positives = 80/217 (36%), Gaps = 29/217 (13%) Query: 44 VAVNGVQLHYQQTG----EGDHAVLLLPGMLGSG-ETDFGP----QLKNLNKKLFTVVAW 94 V + V + Y+ G D+ V++ + S T + P Q + + + ++ Sbjct: 89 VILRDVPVAYKSWGRMNVSRDNCVIVCHTLTSSAHVTSWWPTLFGQGRAFDTSRYFIICL 148 Query: 95 DPRG--YGH----SRPPD----RDFPADFFERDAKDAV----DLMKALKFKK-VSLLGWS 139 + G +G S PD R + A F +D V ++ L ++ +++G S Sbjct: 149 NYLGSPFGSAGPCSPDPDAEGQRPYGAKFPRTTIRDDVRIHRQVLDRLGVRQIAAVVGAS 208 Query: 140 DGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGY 199 GG+ L A P Y+ K+V + + + +E R + K L+ Y Sbjct: 209 MGGMHTLEWAFFGPEYVRKIVPIATSCRQSGWCAAWFETQR---QCIYDDPKYLDGEYDV 265 Query: 200 DYFARTCEKWVDGIRQF--KHLPDGNICRHLLPRVQC 234 D + I K P + H+ P VQ Sbjct: 266 DDQPVRGLETARKIANLTYKSKPAMDERFHMAPGVQA 302 >3I1I-A nrPDB Length = 377 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVS-LLGWSDGGITALIAAAKYPSYIHKMV 160 DFP F A+ +L+K + ++ ++G S GG+ A A YP + +M+ Sbjct: 117 GDEYAMDFPVFTFLDVARMQCELIKDMGIARLHAVMGPSAGGMIAQQWAVHYPHMVERMI 176 Query: 161 IWGANA 166 N Sbjct: 177 GVITNP 182 >5UNO-A nrPDB Length = 492 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 41/234 (17%), Positives = 64/234 (27%), Gaps = 63/234 (26%) Query: 57 GEGDHAVLLLPGMLGSGETDFGPQLKNL------NKKLFTVVAWDPRGYGHSR------- 103 GD L+ G GE+ L + F +V +DPRG SR Sbjct: 68 ATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNS 127 Query: 104 ---------PPDRDFPADFFERD----------------------------AKDAVDLMK 126 P D+ + AKD + Sbjct: 128 DADNDRLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRA 187 Query: 127 ALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA----NAYVTDEDSMIYEGIRDV 182 AL K++ LG+S G A ++P + M++ GA + E Sbjct: 188 ALGDDKLTYLGYSYGTRIGSAYAEEFPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAF 247 Query: 183 SKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPA 236 + ++ K G D + H + PR+ PA Sbjct: 248 NNYAADCAKNAGCPLGADPAKAV---------EVYHSLVDPLVDPDNPRISRPA 292 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 31/207 (14%), Positives = 57/207 (27%), Gaps = 29/207 (14%) Query: 93 AWDPRGYGHSRPPDRD----FPADFFERDAKDAVDLMKA-----LKFKKVSLLGWSDGGI 143 DPRG +S + + ++ +L+ L + + S G Sbjct: 294 TKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHG-- 351 Query: 144 TALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFA 203 + + + VTD D +I E R + + D Sbjct: 352 ---RYNNSGDARVA--INCVDQPPVTDRDKVIDEDRRAREIAPFMS----YGKFTGDAPL 402 Query: 204 RTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSR 263 TC W H P ++V DP P + ++GS Sbjct: 403 GTCAFWPVPPTSQPHAVSAPGL--------VPTVVVSTTHDPATPYKAGVDLANQLRGS- 453 Query: 264 LHLMPEGKHNLHLRFADEFNKLAEDFL 290 L +H + + ++ +L Sbjct: 454 LLTFDGTQHTVVFQGDSCIDEYVTAYL 480 >4QLO-A nrPDB Length = 360 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 34/181 (18%), Positives = 66/181 (36%), Gaps = 16/181 (8%) Query: 35 FGTSVTSAKVAVNGVQLHYQQTG-EGDHAVLLLPGMLG----------SGETDFGPQLKN 83 G +T + ++ ++L Y+ G G V++ + G G Sbjct: 11 LGEFITESGEVIDNLRLRYEHVGYHGQPLVVVCHALTGNHLTYGTDDYPGWWREIIDGGY 70 Query: 84 LNKKLFTVVAWDPRG--YGHSRPPDRD-FPADFFERDAKDAVDL-MKALKFKKVS-LLGW 138 + + + +D G +G S P + FP RD A + ++AL + K++ L+G Sbjct: 71 IPIHDYQFLTFDVIGSPFGSSSPLNDPHFPKKLTLRDIVRANERGIQALGYDKINILIGG 130 Query: 139 SDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYG 198 S GG+ A+ + K +I A + + E R + + G Sbjct: 131 SLGGMQAMELLYNQQFEVDKAIILAATSRTSSYSRAFNEIARQAIHLGGKEGLSIARQLG 190 Query: 199 Y 199 + Sbjct: 191 F 191 >4Q1V-A nrPDB Length = 710 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 48/278 (17%), Positives = 79/278 (28%), Gaps = 72/278 (25%) Query: 16 LLSALKP--GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQ------------------ 55 LL+A P G +P K A LHY+ Sbjct: 444 LLTAENPYDGYQMPSIETGTI--------KAADGTTDLHYRLMKPANFDPAKKYPVIVYV 495 Query: 56 TGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGY---GHSRPPDRDFPAD 112 G + G+ D + K + + D RG G + + F Sbjct: 496 YGGPHAQCVTGGWQNGARGWD-----TYMASKGYIMFTIDNRGSSNRGLTFE-NATFRRL 549 Query: 113 FFERDAKDA--VDLMKAL---KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY 167 E V+ +K+L +++ + GWS GG +YP V G Sbjct: 550 GIEEGKDQVKGVEFLKSLPYVDSERIGVHGWSFGGHMTTALMLRYPEIFKVGVAGGP--- 606 Query: 168 VTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRH 227 V W E +YG E+++D ++ Sbjct: 607 --------------VIDWGY-----YEIMYG--------ERYMDTPESNPEGYKECNLKN 639 Query: 228 LLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLH 265 L +++ LI+H + D H K +R + Sbjct: 640 LADQLKGHLLIIHDDHDDTCVPQHTLSFMKACVDARTY 677 >5EFZ-A nrPDB Length = 361 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 37/265 (13%), Positives = 69/265 (26%), Gaps = 61/265 (23%) Query: 82 KNLNKKLFTVVAWDPRGYGHSRPPDRDF-----PADFFERDAKDAVD----LMKALKFKK 132 + L+ + ++ + G G S P R D L + + Sbjct: 84 RALDPSKYCIIVVNQIGNGLSSSASNTGGSLAGPGFANVRIGDDVSAQHTLLTEYFGIES 143 Query: 133 -VSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRK 191 ++G S G A +YP ++ + A ++ D + E + + + Sbjct: 144 LALVVGGSMGAQQTYEWAVRYPDFVKRAAAIAGTARNSEHDFLFTEILIEAITTDPAFQA 203 Query: 192 PLE-----------------ALYGYD-YFARTCEKWVDGIRQFKHLPD------------ 221 L L G+ F RT G + D Sbjct: 204 GLYRSSSAVAAGLERHAKLWTLMGWSPEFFRTGRHKALGFESMQMFVDGFMKRYFAPMDP 263 Query: 222 ------------GNICRH-------LLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS 262 G++ RH L R++ ++ D K + S Sbjct: 264 NNLLTMAWKWQRGDVSRHTGGDLAKALGRIKAKTYVMPISHDQFFTVDDCLSEQKMIPNS 323 Query: 263 RLHLMPEG-KH-NLHLRFADEFNKL 285 + H L A ++L Sbjct: 324 EFRPLRSIDGHLGLFGTDAQMLDQL 348 >6HIX-BG nrPDB Length = 378 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 34/98 (34%), Gaps = 3/98 (3%) Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAA--KYPSYIHKMVIWGA 164 D D E+ + +M AL + L +S G + A+ A+ ++P + ++ Sbjct: 119 TDSSKDLLEQSCQRICAVMDALDVRWTHFLTYSYGALVAVRMASSQEFPHRVGTLMSLDT 178 Query: 165 NAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYF 202 + E D++K P + L Sbjct: 179 PLVTREFLRN-MEQREDIAKAERDINVPEDGLAFAKQA 215 >3N0T-A nrPDB Length = 469 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 44/147 (29%), Gaps = 17/147 (11%) Query: 54 QQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNK----KLFTVVAWDPRGYGHS------R 103 + G+ + G G F + + + +V + R YG S Sbjct: 39 RFWVRGEGPIFFYTGNEG-DVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS 97 Query: 104 PPDRDFPADFFERDAKDAVDLMKALKFK------KVSLLGWSDGGITALIAAAKYPSYIH 157 E+ D +L++AL+ G S GG+ + KYP + Sbjct: 98 TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA 157 Query: 158 KMVIWGANAYVTDEDSMIYEGIRDVSK 184 + A + RDV+ Sbjct: 158 GALAASAPVLAVAGLGDSNQFFRDVTA 184 >5XB6-A nrPDB Length = 306 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 30/182 (16%), Positives = 52/182 (28%), Gaps = 7/182 (3%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFF-ERDAK 119 A++L G E G K L +K F +A+D G S R + D Sbjct: 35 QAIVLSHPGGGVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDIS 94 Query: 120 DAVDLMKAL---KFKKVSLLGWSDGGITALIAAA--KYPSYIHKMVIWGANAYVTDEDSM 174 +D + L ++ +G G AA + I + + + Sbjct: 95 AVIDYLTTLSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSIFRNGWEN 154 Query: 175 IYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQC 234 + I + + + +Y + + L H PR Q Sbjct: 155 NVKSIDALPYVEAGSNARTSDISSGEYAIMPLAPMKESDAPNEELRQAWEYYHT-PRAQY 213 Query: 235 PA 236 P Sbjct: 214 PT 215 >5OLJ-A nrPDB Length = 723 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 46/252 (18%), Positives = 74/252 (29%), Gaps = 21/252 (8%) Query: 1 MVAVLGGRGVLRLRLLLS--ALKPGIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGE 58 +V+V +G LR L AL+ + R P F T + + +N + Sbjct: 442 VVSVFRSKGAKELRTLEDNVALRERLKAYRYNP-KEFTIIKTQSALELNAWIVKPIDFDP 500 Query: 59 GDHAVLLLPGMLGSGET--------DFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFP 110 H +L+ G D+ L K + V D RG G R Sbjct: 501 SRHYPVLMVQYSGPNSQQVLDRYSFDWEH---YLASKGYVVACVDGRGTGARGEEWRKCT 557 Query: 111 ADFFERDAKD-------AVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWG 163 D A+ + + ++ + GWS GG T L++ + + Sbjct: 558 YMQLGVFESDDQIAAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVA 617 Query: 164 ANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGN 223 A DS+ E K + K AL HL + Sbjct: 618 PVADWRFYDSVYTERFMRTPKENASGYKMSSALDVASQLQGNLLIVSGSADDNVHLQNTM 677 Query: 224 ICRHLLPRVQCP 235 + L + P Sbjct: 678 LFTEALVQANIP 689 >5UGZ-A nrPDB Length = 260 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 25/197 (12%), Positives = 54/197 (27%), Gaps = 16/197 (8%) Query: 100 GHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITA---LIAAAKYPSYI 156 G + + A +K ++ G S GGI A + + + Sbjct: 59 GRGTRIRQPLCLTMVDAVADLYQQFVKHYTGGDYAIFGHSLGGIMAFELVHYILDHGHDM 118 Query: 157 HKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRK----PLEALYGYDYFARTCEKWVDG 212 + + + + E K P++ + + Sbjct: 119 PCALFFSGCRPPDRASHEVILHTLPDQAFMEEIVKLGGTPVDVFRNKELMTIFTPIIKND 178 Query: 213 IRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLH---LMPE 269 R ++ R L CP ++ HG+ D LV + + + +R + P Sbjct: 179 YRLYEQYVFQAKARTL----TCPIVLFHGDADNLVMQD--ELLAWEKFTTRKTRTIIFPA 232 Query: 270 GKHNLHLRFADEFNKLA 286 H + ++ Sbjct: 233 ADHFFVDKHFEQVVGYV 249 >1UFO-A nrPDB Length = 238 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 38/251 (15%), Positives = 74/251 (29%), Gaps = 53/251 (21%) Query: 39 VTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG 98 V + ++ + G+ + + +L L G+ GS E L ++ F ++A+D Sbjct: 3 VRTERLTLAGLSVLARIPEAPKALLLALHGLQGSKEHILA-LLPGYAERGFLLLAFDAPR 61 Query: 99 YGHSRPPDRDFP-----------ADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALI 147 +G P A F+ +A+ + + + L G S G A + Sbjct: 62 HGEREGPPPSSKSPRYVEEVYRVALGFKEEARRVAEEAERRFGLPLFLAGGSLGAFVAHL 121 Query: 148 AAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCE 207 A+ + G+ + + E ++ + EA G Sbjct: 122 LLAEGFRPRGVLAFIGSGFPMKLPQGQVVEDPGVLALYQAPPATRGEAYGG--------- 172 Query: 208 KWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHV----KGSR 263 P L +HG +D +VP + + + R Sbjct: 173 --------------------------VPLLHLHGSRDHIVPLARMEKTLEALRPHYPEGR 206 Query: 264 LHLMP--EGKH 272 L H Sbjct: 207 LARFVEEGAGH 217 >6EOT-A nrPDB Length = 898 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 39/212 (18%), Positives = 67/212 (31%), Gaps = 31/212 (14%) Query: 28 RAGPAAAFGTSVTSAKVAVNGVQLH---YQ----QTGEGDHAVLLLPGMLG--------S 72 AGP + + + G L+ Y+ Q G+ VL + G Sbjct: 623 SAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFK 682 Query: 73 GETDFGPQLKNLNKKLFTVVAWDPRG-YGHSRPPDRDFPADFFERDAKDAVDLMKAL--- 128 G F L + VV D RG + F + + D V+ ++ L Sbjct: 683 GVKYFRLN--TLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASR 740 Query: 129 ----KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSK 184 +V + GWS GG +L A S I ++ I GA + I+ + Sbjct: 741 YDFIDLDRVGIHGWSYGGYLSL-MALMQRSDIFRVAIAGAPVTL-----WIFYDTGYTER 794 Query: 185 WSERTRKPLEALYGYDYFARTCEKWVDGIRQF 216 + + + Y + + + R Sbjct: 795 YMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLL 826 >1DIN-A nrPDB Length = 236 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 29/75 (38%), Gaps = 11/75 (14%) Query: 227 HLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS---RLHLMPEGKHNLHLRFADEF- 282 + +P V+ PAL G +D VP I + + ++H E H+ + + Sbjct: 154 NKVPEVKHPALFHMGGQDHFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTSSSGYV 213 Query: 283 -------NKLAEDFL 290 N+ DFL Sbjct: 214 ASAAALANERTLDFL 228 >3I6Y-A nrPDB Length = 280 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 35/242 (14%), Positives = 70/242 (28%), Gaps = 54/242 (22%) Query: 55 QTGEGDHAVLLLPGMLGSGETDFGPQLKN---LNKKLFTVVAWDPRGYGHSRPPDRDFPA 111 TG + L G+ S E +F + + +VA D G D + Sbjct: 42 STGAKVPVLYWLSGLTCSDE-NFMQKAGAQRLAAELGIAIVAPDTSPRGEGVADDEGYDL 100 Query: 112 D-------------------FFERDAKDAVDLMKAL--KFKKVSLLGWSDGGITALIAAA 150 ++ + +L++++ K ++ G S GG AL A Sbjct: 101 GQGAGFYVNATQAPWNRHYQMYDYVVNELPELIESMFPVSDKRAIAGHSMGGHGALTIAL 160 Query: 151 KYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWV 210 + P + + + + + + + + T E Y R +++V Sbjct: 161 RNPERYQSVSAFSP---INNPVNCPWGQKAFTAYLGKDTDTWRE--YDASLLMRAAKQYV 215 Query: 211 DGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEG 270 PAL+ GE D + + + S + + Sbjct: 216 ------------------------PALVDQGEADNFLAEQLKPEVLEAAASSNNYPLELR 251 Query: 271 KH 272 H Sbjct: 252 SH 253 >2XLB-A nrPDB Length = 320 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 39/249 (15%), Positives = 59/249 (23%), Gaps = 29/249 (11%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERD 117 G H L+ + D + N + RG G S Sbjct: 79 TGPHPALVRFHGYNASYDDGIHDIVNWALHGYATFGMLVRGQGGSEDTSVTPGGHALGWM 138 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPS----YIHKMVIWGANAYVTDEDS 173 K L G + AL +P I VI G+ + Sbjct: 139 TKGI------LSKDTYYYRGVYLDAVRALEVIQSFPEVDEHRIG--VIGGSQGGALAIAA 190 Query: 174 MIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLP-------DGNICR 226 I V E D ++ + P + Sbjct: 191 AALSDIPKVVVADYPYLSNFERAV--DVALEQPYLEINSYFRRNSDPEVEEKAFETLSYF 248 Query: 227 HLLPR---VQCPALIVHGEKDPLVPRFHADFIHKHVK-GSRLHLMPEGKHNLHLRFADEF 282 L+ V+ P L+ G D + P + H++ L + H F F Sbjct: 249 DLINLAGWVKQPTLMAIGLIDQVTPPSTVFAAYNHLETDKELKVYRYFGH----EFIPAF 304 Query: 283 NKLAEDFLQ 291 FLQ Sbjct: 305 QTEKLSFLQ 313 >2EEP-A nrPDB Length = 706 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 48/278 (17%), Positives = 80/278 (28%), Gaps = 48/278 (17%) Query: 16 LLSALKP--GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSG 73 LL A P G +P + + LH+ + V + G Sbjct: 440 LLEAKNPDTGYAMPEIRTGTIMAADGQTPLYYKLTMPLHFDPAKKYPVIVYVYGGPHAQL 499 Query: 74 ET-DFGPQL----KNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFF--ERDAKDA--VDL 124 T + + + +K + V D RG + A VD Sbjct: 500 VTKTWRSSVGGWDIYMAQKGYAVFTVDSRGSANRGAAFEQVIHRRLGQTEMADQMCGVDF 559 Query: 125 MKALKF---KKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRD 181 +K+ + ++ + GWS GG + V G Sbjct: 560 LKSQSWVDADRIGVHGWSYGGFMTTNLMLTHGDVFKVGVAGGP----------------- 602 Query: 182 VSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHG 241 V W+ E +YG YF E G L + L +++HG Sbjct: 603 VIDWNR-----YEIMYGERYFDAPQENPE-GYDAANLLKRAGDLKGRL-------MLIHG 649 Query: 242 EKDPLVPRFHADFIHKHVKGSRL----HLMPEGKHNLH 275 DP+V H+ +R ++ P +HN+ Sbjct: 650 AIDPVVVWQHSLLFLDACVKARTYPDYYVYPSHEHNVM 687 >5AOA-A nrPDB Length = 286 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 40/247 (16%), Positives = 72/247 (29%), Gaps = 29/247 (11%) Query: 42 AKVAVNGVQLH-YQ--QTGEGD---HAVLLLPGMLGSGET-DFGPQLKNLNKKLFTVVAW 94 KV ++L+ Y+ D V G SG F PQ + + +A Sbjct: 21 KKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQCEYFAGRGMVAMAA 80 Query: 95 DPR-GYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYP 153 D R G H+ + A D A+++ + + + Sbjct: 81 DYRVGSRHN------------VKVADCVADAKSAIRWVRQHAAELGVDPQKIVASGGSAG 128 Query: 154 SYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGI 213 ++ + + +ED I + + L D+ R + W + + Sbjct: 129 GHLAACTVMVPDLEAPEEDHTI--SSQANAAILFNPVLILSREGLKDHVPR--QDWEERL 184 Query: 214 R-QFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGS----RLHLMP 268 R + P H + P +I HG D VP + +K + L Sbjct: 185 RERLGTEPKAVSPYHHIRAGLPPMIIFHGTADNTVPFETIRLFAEAMKKAGNRCELVPFE 244 Query: 269 EGKHNLH 275 H Sbjct: 245 GAAHGFF 251 >2PL5-A nrPDB Length = 366 Score = 37.8 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLL-GWSDGGITALIAAAKYPSYIHKMV 160 S P FP + K L+++L +K+ + G S GG+ AL + YP+ + + Sbjct: 115 STPYGSRFPFVSIQDMVKAQKLLVESLGIEKLFCVAGGSMGGMQALEWSIAYPNSLSNCI 174 Query: 161 IWGANA 166 + + A Sbjct: 175 VMASTA 180 >2HDW-A nrPDB Length = 367 Score = 37.8 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 44/265 (16%), Positives = 80/265 (30%), Gaps = 55/265 (20%) Query: 54 QQTGEGDHAVLLLPGMLGS-GETDFGPQLKNLNKKLFTVVAWDPRGYGHS-RPPDRDFPA 111 + G +++ G G+ E G + + ++ F +A+DP G S P Sbjct: 89 KNRGGDRLPAIVIGGPFGAVKEQSSGLYAQTMAERGFVTLAFDPSYTGESGGQPRNVASP 148 Query: 112 DFFERDAKDAVD---LMKALKFKKVSLLGW-SDGGITALIAAAKYPSYIHKMVIWGANAY 167 D D AVD L+ + +++ ++G GG+ A + +V + Sbjct: 149 DINTEDFSAAVDFISLLPEVNRERIGVIGICGWGGMALNAVAVD--KRVKAVV----TST 202 Query: 168 VTDEDSMIYEGIRDVSKWSERTR---------------------------KPLEALYGYD 200 + D ++ +G D +RTR K EA + D Sbjct: 203 MYDMTRVMSKGYNDSVTLEQRTRTLEQLGQQRWKDAESGTPAYQPPYNELKGGEAQFLVD 262 Query: 201 YFARTCEKWVDGIRQFKHLPDGNICRHL----------LPRVQ-CPALIVHGE--KDPLV 247 Y R + L + + P L++HGE Sbjct: 263 YHDYYMTPRGYHPRAVNSGNAWTMTTPLSFMNMPILTYIKEISPRPILLIHGERAHSRYF 322 Query: 248 PRFHADFIHKHVKGSRLHLMPEGKH 272 + L ++P H Sbjct: 323 SETAYAAAAEPK---ELLIVPGASH 344 >2ECF-A nrPDB Length = 741 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 39/238 (16%), Positives = 72/238 (30%), Gaps = 54/238 (22%) Query: 69 MLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKAL 128 G G+ F + L ++ + V + D RG P R + V++ L Sbjct: 536 WPGRGDHLFN---QYLAQQGYVVFSLDNRGT-----PRRGRDFGGALYGKQGTVEVADQL 587 Query: 129 ------------KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIY 176 ++ + GWS+GG L+ AK G + + Sbjct: 588 RGVAWLKQQPWVDPARIGVQGWSNGGYMTLMLLAKASDSYA----CGVAGAPVTDWGLYD 643 Query: 177 EGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPA 236 + E+++D + + ++ P Sbjct: 644 --------------------------SHYTERYMDLPARNDAGYREARVLTHIEGLRSPL 677 Query: 237 LIVHGEKDPLVPRFHADFIHKHVKGS----RLHLMPEGKHNLHLRFADEFNKLAEDFL 290 L++HG D V ++ + ++ L P KH L A ++AE FL Sbjct: 678 LLIHGMADDNVLFTNSTSLMSALQKRGQPFELMTYPGAKHGLSGADALHRYRVAEAFL 735 >6EOR-A nrPDB Length = 869 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 43/227 (18%), Positives = 76/227 (33%), Gaps = 46/227 (20%) Query: 81 LKNLNKKLFTVVAWDPRGY--------GHSRPPDRDFPADFFERDAKDAVDLMKALKFKK 132 L L + VV D RG G + + + + + + Sbjct: 664 LNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSR 723 Query: 133 VSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKP 192 V++ GWS GG +L+ P + K+ I G P Sbjct: 724 VAIHGWSYGGFLSLMGLIHKPQ-VFKVAIAG---------------------------AP 755 Query: 193 LEALYGYDYFARTCEKWVDGIRQFKHL-PDGNICRHLLPRVQCP--ALIVHGEKDPLVPR 249 + YD E+++D +H G++ H+ P LI+HG D V Sbjct: 756 VTVWMAYDT--GYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHF 813 Query: 250 FHADFIHKHVKGS----RLHLMPEGKHNLHL-RFADEFNKLAEDFLQ 291 FH +F+ + + +L + P +H++ + + FLQ Sbjct: 814 FHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQ 860 >3AZQ-A nrPDB Length = 662 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 36/233 (15%), Positives = 69/233 (29%), Gaps = 30/233 (12%) Query: 42 AKVAVNGVQLHYQQT--------GEGDH----AVLLLPGMLGSGETDFGPQLKNLNKKLF 89 A +G ++H G D V+ G + + Sbjct: 395 TFTAPDGREIHAHIYPPHSPDFTGPADELPPYVVMAHGGPTSRVPAVLDLDVAYFTSRGI 454 Query: 90 TVVAWDPRG-YGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIA 148 V + G G+ R + D +D + AL + G Sbjct: 455 GVADVNYGGSTGYGRAYRERLRGRWGVVDVEDCAAVATALAEE---------GTADRARL 505 Query: 149 AAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEK 208 A + + + + + D+ W++ E+ Y D+ + E+ Sbjct: 506 AVRGGAAGGWTAASSLVSTDVYACGTVLYPVLDLLGWADGGTHDFESRY-LDFLIGSFEE 564 Query: 209 WVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG 261 + + R L + RV+ P L++ G +DP+ P D + V G Sbjct: 565 FPERYRDRAPLTRAD-------RVRVPFLLLQGLEDPVCPPEQCDRFLEAVAG 610 >3FNB-A nrPDB Length = 405 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 30/208 (14%), Positives = 70/208 (33%), Gaps = 9/208 (4%) Query: 59 GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDA 118 ++++ G S E F + + + V+ D G G + P++ + R A Sbjct: 158 AQDTLIVVGGGDTSREDLFYMLGYSGWEHDYNVLMVDLPGQGKN--PNQGLHFEVDARAA 215 Query: 119 -KDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE 177 +D +A +K+++ G+S GG A + I + V + + + Sbjct: 216 ISAILDWYQA-PTEKIAIAGFS-GGGYFTAQAVEKDKRIKAWIASTPIYDVAEVFRISFS 273 Query: 178 GIRDVSKWSERTRKPLE-ALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLL---PRVQ 233 K + L ++ W G F + + + + ++ Sbjct: 274 TALKAPKTILKWGSKLVTSVNKVAEVNLNKYAWQFGQVDFITSVNEVLEQAQIVDYNKID 333 Query: 234 CPALIVHGEKDPLVPRFHADFIHKHVKG 261 P+L + G + + ++ + K Sbjct: 334 VPSLFLVGAGEDSELMRQSQVLYDNFKQ 361 >3FCX-A nrPDB Length = 282 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 33/170 (19%), Positives = 54/170 (31%), Gaps = 27/170 (15%) Query: 85 NKKLFTVVAWD--PRGY---GHSRPPDRDFPADFFERDAKD-----------AVDLMKAL 128 ++ V+A D PRG G D A F+ +D + + L Sbjct: 72 SEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQL 131 Query: 129 -------KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRD 181 +++S+ G S GG ALI A K P K A A + + + G + Sbjct: 132 INANFPVDPQRMSIFGHSMGGHGALICALKNP---GKYKSVSAFAPICNPVLCPW-GKKA 187 Query: 182 VSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPR 231 S + + +A +D + + LLP Sbjct: 188 FSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPD 237 >3QMW-A nrPDB Length = 259 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 40/223 (17%), Positives = 67/223 (30%), Gaps = 36/223 (16%) Query: 68 GMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKA 127 G S + +L + VV G G R+ P D E A+ D ++ Sbjct: 40 GGTVSAFRGWQERLGDEV----AVVPVQLPGRGLR---LRERPYDTMEPLAEAVADALEE 92 Query: 128 LKFKK-VSLLGWSDGGITALIAAA----KYPSYIHKMVIWGANAYVTDEDSMIYEGIRDV 182 + +L G S G + A A + + + G+ A +Y D Sbjct: 93 HRLTHDYALFGHSMGALLAYEVACVLRRRGAPRPRHLFVSGSRA------PHLYGDRADH 146 Query: 183 SKWSERTRKPLEALYGYDY-----FARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL 237 + R+ + L G D A + + + H P + CP Sbjct: 147 TLSDTALREVIRDLGGLDDADTLGAAYFDRRLPVLRADLRACERYD--WHPRPPLDCPTT 204 Query: 238 IVHGEKDPLV---------PRFHADFIHKHVKGSRLHLMPEGK 271 DP+ P F+ +H+ G+ H G Sbjct: 205 AFSAAADPIATPEMVEAWRPYTTGSFLRRHLPGN--HFFLNGG 245 >6IGR-A nrPDB Length = 656 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 41/235 (17%), Positives = 70/235 (29%), Gaps = 46/235 (19%) Query: 57 GEGDHAVLL--LPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG------------YGHS 102 GE LL G F + + + + + V +PRG YG Sbjct: 423 GEQKVPALLNIHGGPHTDYGHGFTHEFQLMAARGYGVCYSNPRGSVGYGQAWVDAIYGR- 481 Query: 103 RPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIW 162 AD ++ + L K +++G + GG Sbjct: 482 ---WGTVDADDLLNFFDRCLEAVPRLDAAKTAVMGGAYGGFMTNWITGH----------- 527 Query: 163 GANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDG 222 + ++ I ++ + + L +D +D R+ L Sbjct: 528 ----TTRFQAAITDRCISNLISFGGTSDIGLR---FWDDELG-----LDFSRRADALKLW 575 Query: 223 NICR-HLLPRVQCPALIVHGEKDPLVPRFHADF----IHKHVKGSRLHLMPEGKH 272 ++ + V+ P LIVH D P A+ +HKH R PE H Sbjct: 576 DLSPLQYVENVKTPTLIVHSVLDHRCPVEQAEQWYAALHKHQVPVRFVRFPEENH 630 >6BFZ-A nrPDB Length = 449 Score = 37.5 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 15/50 (30%), Gaps = 3/50 (6%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGS 72 G H+ G S V + G ++ G+ V + G Sbjct: 1 GSHMASMTGGQQMGRGSMSKIVKIIGREI---IDSRGNPTVEAEVHLEGG 47 >4XCH-A nrPDB Length = 194 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 21/78 (26%), Gaps = 6/78 (7%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLP-GMLGSGETDF---- 77 G H+ G +V V +L + ++ G G T+F Sbjct: 18 GSHMASMTGGQQMGRGSMKKEVTVESFELDHTIVKAPYIRLISEEVGPKGDIITNFDIRL 77 Query: 78 -GPQLKNLNKKLFTVVAW 94 P ++ + Sbjct: 78 IQPNENAMDTAGLHTIEH 95 >5V41-A nrPDB Length = 286 Score = 36.7 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 54/187 (28%), Gaps = 26/187 (13%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERD 117 G + + G + P L L D YG ER Sbjct: 18 AGGKVPVFVFHPAGGSTVVYEPLLGRLPA--------DTPMYG-----FERVEGSIEERA 64 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE 177 + L++ L+GWS GG+ A A + K V + I + Sbjct: 65 QQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGL-RRLGKDVRFVGLIDAVRAGEEIPQ 123 Query: 178 GIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLL-----PRV 232 ++ K +R E + A Q + L D R +L V Sbjct: 124 TKEEIRKRWDRYAAFAEKTFNVTIPAI-------PYEQLEELDDEGQVRFVLDAVSQSGV 176 Query: 233 QCPALIV 239 Q PA I+ Sbjct: 177 QIPAGII 183 >3E4D-A nrPDB Length = 278 Score = 36.7 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 48/155 (30%), Gaps = 19/155 (12%) Query: 103 RPPDRDFPADFFERDAKDAVDLMKA---LKFKKVSLLGWSDGGITALIAAAKYPSYIHKM 159 P + + ++ L+ + S+ G S GG A+ A K P Sbjct: 110 EEPWSEH-YQMYSYVTEELPALIGQHFRADMSRQSIFGHSMGGHGAMTIALKNPERFKSC 168 Query: 160 -----VIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIR 214 ++ ++A ++ Y G D + W +A + AR E +D + Sbjct: 169 SAFAPIVAPSSADWSEPALEKYLGA-DRAAWRR-----YDACSLVEDGARFPEFLIDQGK 222 Query: 215 QFKHLPDGNICRHLLPRVQCP----ALIVHGEKDP 245 L G ++ L +H D Sbjct: 223 ADSFLEKGLRPWLFEEAIKGTDIGLTLRMHDRYDH 257 >3VT2-A nrPDB Length = 526 Score = 36.7 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 21/57 (36%), Gaps = 5/57 (8%) Query: 23 GIHVPRAGPAAAFGTSVTSAK--VAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDF 77 G H+ G A V VNG Q ++ T G+ GML G+ + Sbjct: 18 GSHMASMTGGQQMGRGSEFAAEGVIVNGTQ--FKDT-SGNVIHAHGGGMLKHGDYYY 71 >4NRS-A nrPDB Length = 449 Score = 36.7 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 7/24 (29%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV 46 G H+ G A V + Sbjct: 18 GSHMASMTGGQQMGRGSEFAFVKI 41 >3N2Z-B nrPDB Length = 446 Score = 36.7 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 47/143 (32%), Gaps = 23/143 (16%) Query: 39 VTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRG 98 V NG + + EGD D +LK + +V + R Sbjct: 29 VADKYWKKNGGSILFYTGNEGDIIWFCNNTGF---MWDVAEELKAM------LVFAEHRY 79 Query: 99 YG-------HSRPPDRDFPADFFERDAKDAVDLMKALK-------FKKVSLLGWSDGGIT 144 YG +S R E+ D +L+K LK + V +G S GG+ Sbjct: 80 YGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGML 139 Query: 145 ALIAAAKYPSYIHKMVIWGANAY 167 A KYP + + A + Sbjct: 140 AAWFRMKYPHMVVGALAASAPIW 162 >3D2A-A nrPDB Length = 181 Score = 36.3 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 38/120 (31%), Gaps = 18/120 (15%) Query: 59 GDHAVLLLPGMLGSGETDFGPQLKNLNKKL------FTVVAWDPRGYGHSRPPDRDFPAD 112 +H +++ +G +F L + + V WD G ++ P Sbjct: 1 AEHNPVVMVHGIGGASFNFAGIKSYLVSQGWSRDKLYAVDFWDKTGTNYNNGPVLS---- 56 Query: 113 FFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAA--AKYPSYIHKMVIWGANAYVTD 170 + ++ KKV ++ S GG L + + +V G +T Sbjct: 57 ------RFVQKVLDETGAKKVDIVAHSMGGANTLYYIKNLDGGNKVANVVTLGGANRLTT 110 >6BA9-A nrPDB Length = 263 Score = 36.3 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 33/235 (14%), Positives = 71/235 (30%), Gaps = 15/235 (6%) Query: 63 VLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAV 122 +++ P GS Q + L ++V W R P R + A Sbjct: 17 LVMCPFAGGSSSAFRHWQAEQLADCALSLVTWPGRDRLRHLEPLRS-----ITQLAALLA 71 Query: 123 DLMKALKFKKVSLL--GWSDGGITALIAAAKYPSY---IHKMVIWGANAYVTDEDSMIY- 176 + ++A LL G + G A ++I G +A + + Sbjct: 72 NELEASVSPDTPLLLAGHAMGAQVAFETCRLLEQRGLAPQGLIISGCHAPHLHSERQLSH 131 Query: 177 -EGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCP 235 + +++ + E + + + + P ++ P Sbjct: 132 RDDADFIAELIDIGGCSPELRENQELMSLFLPLLRADFYATESYHY--DSPDVCPPLRTP 189 Query: 236 ALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADE-FNKLAEDF 289 AL++ G D D + + ++ +G H ++ A F ++ F Sbjct: 190 ALLLCGSHDREASWQQVDAWRQWLSHVTGPVVIDGDHFYPIQQARSFFTQIVRHF 244 >2PPL-A nrPDB Length = 485 Score = 36.3 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 39/109 (35%), Gaps = 19/109 (17%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTV-----VAWDPRGYGHSRPPDRDFPADFFERDA 118 ++ G + G+ + + ++ KKLF V + D + A+ Sbjct: 99 FIIHGFIDKGDESW---VTDMCKKLFEVEEVNCICVD---WKKGSQATYTQAANNVRVVG 152 Query: 119 KDAVDLMKALKFK------KVSLLGWSDGGITALIAAAKYP--SYIHKM 159 ++ L + KV L+G S G A A +K P S I + Sbjct: 153 AQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGL 201 >5W8P-A nrPDB Length = 370 Score = 35.9 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 2/70 (2%) Query: 104 PPDRD-FPADFFERDAKDAVDLMKALKFKK-VSLLGWSDGGITALIAAAKYPSYIHKMVI 161 P FP V + L + +++G S GG AL A +P + ++ Sbjct: 114 KPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGSMGGARALEWAVMHPDAVRAALV 173 Query: 162 WGANAYVTDE 171 A T + Sbjct: 174 LAVGARATGD 183 >3PLN-A nrPDB Length = 424 Score = 35.9 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 5/27 (18%), Positives = 9/27 (33%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGV 49 G H+ G K+ ++G Sbjct: 18 GSHMASMTGGQQMGRGSEFMKITISGT 44 >3TEJ-A nrPDB Length = 329 Score = 35.9 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 40/254 (15%), Positives = 75/254 (29%), Gaps = 28/254 (11%) Query: 5 LGGRGVLRLRLLLSALKPGIHVPR-AGPAAAF-GTSVTSAKVAVNGVQLHYQQTG----- 57 LGG +L ++L A + V R P ++V ++ + ++ G Sbjct: 38 LGGHXLLAMKL---AAQLSRQVARQVTPGQVMVASTVAKLATIIDAEEDSTRRMGFETIL 94 Query: 58 ---EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRD--FPAD 112 EG+ L F + L ++++ S P+ A+ Sbjct: 95 PLREGNGPTLFCFHPASGFAWQFSVLSRYL-DPQWSIIGI------QSPRPNGPMQTAAN 147 Query: 113 FFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDED 172 E L++ LLG+S GG A AA+ + ++ G E Sbjct: 148 LDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQGIAARLRARGEQVAFLGLLDTWPPET 207 Query: 173 SMIYEGIRDVSKWS----ERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHL 228 E ++ + + EA + + E + + H Sbjct: 208 QNWQE--KEANGLDPEVLAEINREREAFLAAQQGSTSTELFTTIEGNYADAVRLLTTAHS 265 Query: 229 LPRVQCPALIVHGE 242 +P L V Sbjct: 266 VPFDGKATLFVAER 279 >1HLG-A nrPDB Length = 371 Score = 35.9 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 40/264 (15%), Positives = 77/264 (29%), Gaps = 32/264 (12%) Query: 44 VAVNGVQLHYQQTGE-GDHAVLLLPGMLGSGETDFGPQLKN------LNKKLFTVVAWDP 96 + VN + + +G G V+ L L + T++ L N L + V + Sbjct: 32 LEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNS 91 Query: 97 RG--YGHSRPPDRDFPADFFERDAKDAVD---------LMKALKFKKVSLLGWSDGGITA 145 RG + +F+ + ++K K++ +G S G Sbjct: 92 RGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIG 151 Query: 146 LIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFART 205 IA + PS ++ Y + + ++K + + ++G F Sbjct: 152 FIAFSTNPSLAKRI----KTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIF--Y 205 Query: 206 CEKWVDGIRQFKHLPDGNICRHLLPRVQCPAL-IVHGEKDPLVPRFHADFIHKHVKGSRL 264 + D L R +L + AL I+ G D H Sbjct: 206 PHNFFDQF-----LATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTS 260 Query: 265 HLMPEGKHNLHLRFADEFNKLAED 288 + H + +F Sbjct: 261 --VQNMFHWTQAVKSGKFQAYDWG 282 >4IXL-A nrPDB Length = 244 Score = 35.5 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 29/110 (26%), Gaps = 9/110 (8%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV---NGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGP 79 G H+ G + +G + + G ++ L G S E Sbjct: 18 GSHMASMTGGQQMGRGSQITGNEIGTHDGYDYEFWKDEGGYGSMTLNSGGTFSAEWTDVH 77 Query: 80 QLKNLNKKLF-TVVAWDPRG-----YGHSRPPDRDFPADFFERDAKDAVD 123 + + F T G YG + P+ + V+ Sbjct: 78 NILFRKGQKFDTTQTHQQLGNINIDYGVNYQPNGSSYLAVYGWTTDPLVE 127 >3LA8-A nrPDB Length = 303 Score = 35.1 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 18/81 (22%), Gaps = 7/81 (8%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G S + + G L+ G + Sbjct: 18 GSHMASMTGGQQMGRGSMSLLKKIYETRDFLTAKGVQKPEFGLILGSGLGELAEEIENAL 77 Query: 83 NLNKKLFTVVAWDPRGYGHSR 103 LN D +G S Sbjct: 78 VLNYA-------DIPNWGRST 91 >5CHZ-A nrPDB Length = 192 Score = 35.1 bits (79), Expect = 0.033, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 49/155 (31%), Gaps = 25/155 (16%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G ++ + +++ L+ L Sbjct: 18 GSHMASMTGGQQMGRGSEFMALSPPRRK-AFKKWTPPRSPFNLVQETLFHDPWKLLIATI 76 Query: 83 NLNKKLFTVVAWDPRGYGHSRPPD-----RDFPADFFERDAK--DAVDLMKALKFKKV-- 133 LN R G P +P+ R A D +L+K L + Sbjct: 77 FLN-----------RTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRA 125 Query: 134 -SLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY 167 +++ +SD +T KYP +H + +G ++Y Sbjct: 126 KTIVKFSDEYLTKQW---KYPIELHGIGKYGNDSY 157 >3H2H-A nrPDB Length = 397 Score = 35.1 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 41/105 (39%), Gaps = 8/105 (7%) Query: 78 GPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPAD--------FFERDAKDAVDLMKALK 129 P + L + + VV D G G S + R A+ + +K Sbjct: 107 DPLVTRLASQGYVVVGSDYLGLGKSNYAYHPYLHSASEASATIDAMRAARSVLQHLKTPL 166 Query: 130 FKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSM 174 KV L G+S GG TA+ + +++ K A+A ++ ++ Sbjct: 167 SGKVMLSGYSQGGHTAMATQREIEAHLSKEFHLVASAPISGPYAL 211 >4X97-A nrPDB Length = 380 Score = 34.8 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 51/139 (36%), Gaps = 19/139 (13%) Query: 46 VNGVQLHYQQTGE----GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 ++ ++L Y +T D + +PG + +F K+ F + G+G+ Sbjct: 59 IDNIRLVYNKTSRATQFPDGVDVRVPGFGKTFSLEFLDPSKSSVGSYFHTMVESLVGWGY 118 Query: 102 SR-PPDRDFPADF---------FERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAK 151 +R R P D+ + ++ ++ M L V L+ S G + L + Sbjct: 119 TRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQLYGGPVVLVAHSMGNMYTLYFLQR 178 Query: 152 YPS-----YIHKMVIWGAN 165 P YI V GA Sbjct: 179 QPQAWKDKYIRAFVSLGAP 197 >1LPA-B nrPDB Length = 449 Score = 34.8 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 22/165 (13%), Positives = 52/165 (31%), Gaps = 13/165 (7%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQL-KNLNK-KLFTVVAWDPRG 98 +VA + + ++ G + GE ++ + KNL K + + D +G Sbjct: 50 FQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCICVDWKG 109 Query: 99 YGHSRPPDRDFPADFFERDAKDAVDLMK-ALKF--KKVSLLGWSDGGITALIAAAKYPSY 155 + + V+ ++ A + V ++G S G AA + Sbjct: 110 GSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAH----AAGEAGRR 165 Query: 156 IHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYD 200 + + D ++G ++ + + + D Sbjct: 166 TNGTI---GRITGLDPAEPCFQGTPELVRLD-PSDAKFVDVIHTD 206 >1THT-A nrPDB Length = 305 Score = 34.8 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 35/236 (14%), Positives = 66/236 (27%), Gaps = 18/236 (7%) Query: 46 VNGVQLHYQQTGEGDHAVL-----LLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGY- 99 NG +LH +T ++ L+ F + L+ F V +D + Sbjct: 15 NNGQELHVWETPPKENVPFKNNTILIASGFARRMDHFAGLAEYLSTNGFHVFRYDSLHHV 74 Query: 100 GHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKM 159 G S +F + ++ + + L+ S + A + S + Sbjct: 75 GLSSGSIDEFTMTTGKNSLCTVYHWLQTKGTQNIGLIAASL----SARVAYEVISDLELS 130 Query: 160 VIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHL 219 + A V D++ E S E D+ V F+H Sbjct: 131 FLITAVGVVNLRDTL--EKALGFDYLSLPID---ELPNDLDFEGHKLGSEVFVRDCFEHH 185 Query: 220 PDG-NICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMP--EGKH 272 D + + P + D V + + H++ L H Sbjct: 186 WDTLDSTLDKVANTSVPLIAFTANNDDWVKQEEVYDMLAHIRTGHCKLYSLLGSSH 241 >5YAL-A nrPDB Length = 342 Score = 34.8 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 36/242 (14%), Positives = 73/242 (30%), Gaps = 33/242 (13%) Query: 26 VPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEG-------DHAVLLLPGMLGSGETDFG 78 +P PAA + + S V N V + +++L G Sbjct: 50 LPSREPAAPYVSKPLSRAVLGNDVLAGVRTHAVAGARPAPVPRPLVVLSPGFGMSRITLT 109 Query: 79 PQLKNLNKKLFTVVAWDP--------RGYGHSRP-----PDRDFPADFFERDAKDAVDLM 125 ++L + + V A D G G R P AKD ++ Sbjct: 110 ALGEDLASRGYAVAAVDHTYEAPVEFPG-GRIEKCTLCDDSRMDPGAVVRNRAKDLRFVL 168 Query: 126 KAL---------KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIY 176 L +++ + G S GG +A+ + + + N + + Sbjct: 169 DRLTGPGSELRVDARRIGVAGHSIGGASAVEV-MREDRRVDAAINLDGNFFTEPPAEGLN 227 Query: 177 EGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPA 236 + + + +P E ++W+D + H+ ++ ++ R P Sbjct: 228 KPVLLLGARRSGLPEPQENWERAWKQLTGWKRWLD-VPAGGHMTFTDVPW-IVDRFGMPG 285 Query: 237 LI 238 I Sbjct: 286 QI 287 >5JKJ-A nrPDB Length = 370 Score = 34.8 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 11/89 (12%) Query: 81 LKNLNKKLFTVVAWDPRGYGHSRPPDRD--FPADFFERDAKDAV----DLMKALKFKK-V 133 L NLN V+ P S PD + DF +D V L+++L K Sbjct: 90 LANLNAYDPHVITTGP----TSINPDTGKPYGLDFPVVTIRDFVNVQKALLESLGISKLY 145 Query: 134 SLLGWSDGGITALIAAAKYPSYIHKMVIW 162 +++G S G + A+ A+ YP ++ +M+ Sbjct: 146 AVIGPSMGSMQAIDWASAYPGWVERMISV 174 >3L86-A nrPDB Length = 279 Score = 34.4 bits (77), Expect = 0.056, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 22/86 (25%), Gaps = 14/86 (16%) Query: 23 GIHVPRAGPAAAFGTSVTSAK--VAVNGV-----------QLHYQQTGEGDHAVLLLPGM 69 G H+ G + + GV Q+ Q G V++ G Sbjct: 18 GSHMASMTGGQQMGRGSMKDIIVIKIGGVASQQLSGDFLSQIKNWQD-AGKQLVIVHGGG 76 Query: 70 LGSGETDFGPQLKNLNKKLFTVVAWD 95 + Q+ V + D Sbjct: 77 FAINKLMEENQVPVKKINGLRVTSKD 102 >3U31-A nrPDB Length = 290 Score = 34.4 bits (77), Expect = 0.057, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 10/85 (11%) Query: 23 GIHVPRAGPAAAFGTSVTS----AKVAVNGVQLHYQQTGEGDHA---VLLLPGMLGSGET 75 G H+ G + + + + ++ + V+ L G S E+ Sbjct: 1 GSHMASMTGGQQMGRGSMGNLMISFLKKDTQSITLEELAKIIKKCKHVVALTGSGTSAES 60 Query: 76 DFGPQLKNLNKKLFTVVAWDPRGYG 100 + P + + +++ +DPR YG Sbjct: 61 N-IPSFRGSSNSIWS--KYDPRIYG 82 >3L7V-A nrPDB Length = 295 Score = 34.4 bits (77), Expect = 0.059, Method: Composition-based stats. Identities = 4/26 (15%), Positives = 8/26 (30%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNG 48 G H+ G + + +G Sbjct: 18 GSHMASMTGGQQMGRGSMTKHIHWDG 43 >5T6O-A nrPDB Length = 389 Score = 34.4 bits (77), Expect = 0.064, Method: Composition-based stats. Identities = 19/154 (12%), Positives = 43/154 (27%), Gaps = 16/154 (10%) Query: 140 DGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGY 199 GG A + + + +++ + +++ + D + T P + L+ Sbjct: 174 LGGGAGAPCAL-----LRGLELANTFSFLR-PNDLVWNYVVD-NYLKGNTPVPFDLLFWN 226 Query: 200 DYFARTCEKWVDGIRQFKHLPDGNICRH---------LLPRVQCPALIVHGEKDPLVPRF 250 W + +L + L + P I +D +VP Sbjct: 227 GDATNLPGPWYCWYLRHTYLQNELKVPGKLTVCGVPVDLASIDVPTYIYGSREDHIVPWT 286 Query: 251 HADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNK 284 A + ++ H + NK Sbjct: 287 AAYASTALLANKLRFVLGASGHIAGVINPPAKNK 320 >4F1R-A nrPDB Length = 293 Score = 34.4 bits (77), Expect = 0.064, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 11/28 (39%), Gaps = 1/28 (3%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQ 50 G H+ G + V VNG+Q Sbjct: 20 GSHMASMTGGQQMGR-MRIISVNVNGIQ 46 >5YP1-A nrPDB Length = 745 Score = 34.4 bits (77), Expect = 0.066, Method: Composition-based stats. Identities = 51/294 (17%), Positives = 87/294 (29%), Gaps = 72/294 (24%) Query: 15 LLLSALKPGIHVPRAGPAAAFGTSVTSAKVAVNGVQ-LHYQQ--------TGEGDHAVLL 65 LL++ + H P A AA + A +G LHY + V + Sbjct: 468 LLVNDVSDATH-PYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFV 526 Query: 66 LPGMLG-------SGETD-FGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERD 117 G G +D F Q L ++ + V D RG P R Sbjct: 527 YGGPAAQTVTRAWPGRSDSFFNQ--YLAQQGYVVFTLDNRGT-----PRRGAAFGGALYG 579 Query: 118 AKDAVDLMKAL------------KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165 + V++ L ++ + GWS+GG L+ AK+ G Sbjct: 580 KQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYA----CGVA 635 Query: 166 AYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNIC 225 V+ W+ Y E+++D + + Sbjct: 636 GAP-------------VTDWAL-------------YDTHYTERYMDLPKANEAGYREASV 669 Query: 226 RHLLPRVQC-PALIVHGEKDPLVPRFHADFIHKHVKGS----RLHLMPEGKHNL 274 + + L++HG D V ++ + ++ L P KH L Sbjct: 670 FTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGL 723 >4FS9-A nrPDB Length = 409 Score = 34.0 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 53/174 (30%), Gaps = 14/174 (8%) Query: 107 RDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANA 166 F +L AL++ L+G ++ AA++ + + ++ Sbjct: 112 SGFTGQLVRVRLASLSELEDALQYDMEELVGSAEFARQVDAIAARHGKTLRIHMALNSSG 171 Query: 167 YVTDEDSMI-YEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNIC 225 + M + G + + +++ L AL + + + G+ F D I Sbjct: 172 MSRNGVEMATWSGRGEALQITDQKHLKLVALMTH-FAVEDKDDVRKGLAAFNEQTDWLIK 230 Query: 226 RHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFA 279 L R + L +H V +RL ++ G Sbjct: 231 HAKLDRSK---LTLHAANSFATLE---------VPEARLDMVRTGGALFGDTVP 272 >4EB0-A nrPDB Length = 258 Score = 34.0 bits (76), Expect = 0.076, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 34/103 (33%), Gaps = 5/103 (4%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTVVAWD---PRGYGHSRPPDRDFPADFFERDAKD 120 + + + + + L F V+ + Y SR ++ + Sbjct: 54 IAMSPGYTADASSLAWLGRRLASHGFVVLVINTNSRFDYPDSRASQLSAALNYLRTSSPS 113 Query: 121 AVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWG 163 AV L ++++ G S GG L A + PS + + Sbjct: 114 AVR--ARLDANRLAVAGHSMGGGGTLRIAEQNPSLKAAVPLTP 154 >4M02-A nrPDB Length = 204 Score = 34.0 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 18/74 (24%), Gaps = 7/74 (9%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETD-FGPQL 81 G H+ G ++ Q+ Y G + + Q Sbjct: 18 GSHMASMTGGQQMGRGSSAV------TQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQ 71 Query: 82 KNLNKKLFTVVAWD 95 L K + + D Sbjct: 72 SALTAKGYNYTSVD 85 >4E1Q-A nrPDB Length = 207 Score = 33.6 bits (75), Expect = 0.096, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 21/83 (25%), Gaps = 12/83 (14%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G S +A V G +++ + Sbjct: 18 GSHMASMTGGQQMGRG--SEFMANPRVFFDMTVGGAPAGRIVM----------ELYKDAV 65 Query: 83 NLNKKLFTVVAWDPRGYGHSRPP 105 + F + +G G S P Sbjct: 66 PRTVENFRALCTGEKGVGKSGKP 88 >1AUO-A nrPDB Length = 218 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 32/91 (35%), Gaps = 6/91 (6%) Query: 101 HSRPPDRDFPADFFERDAKDAVDLMKA-----LKFKKVSLLGWSDGGITALIAA-AKYPS 154 + P R + E AK DL++A + ++ L G+S GG A + Sbjct: 71 KAMSPARSISLEELEVSAKMVTDLIEAQKRTGIDASRIFLAGFSQGGAVVFHTAFINWQG 130 Query: 155 YIHKMVIWGANAYVTDEDSMIYEGIRDVSKW 185 + ++ A ++ + + + Sbjct: 131 PLGGVIALSTYAPTFGDELELSASQQRIPAL 161 >5X6S-A nrPDB Length = 275 Score = 33.2 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 19/121 (15%), Positives = 34/121 (28%), Gaps = 10/121 (8%) Query: 48 GVQLHY-QQTGEGDHAVLLLPGMLGSGETDFG-PQLKNLNKK-LFTVVAWDPRGYGHSRP 104 G+ ++ V+ + G+G +G L+++ F V+ G Sbjct: 18 GMYIYVPNNLASNPGIVVAIHYCTGTGPGYYGDSPYATLSEQYGFIVIYPSSPYSGGCWD 77 Query: 105 PDRDFP-----ADFFERDAKDAVDLMKALKFK--KVSLLGWSDGGITALIAAAKYPSYIH 157 A + KV + G S G + + AA YP Sbjct: 78 VSSQATLTHNGGGNSNSIANMVTWTISKYGADSSKVFVTGSSSGAMMTNVMAATYPELFA 137 Query: 158 K 158 Sbjct: 138 A 138 >5Z9R-A nrPDB Length = 281 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 9/72 (12%), Positives = 13/72 (18%), Gaps = 14/72 (19%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G K + VLL G + Sbjct: 18 GSHMASMTGGQQMGRGSEFMKNRI--------------PVVLLACGSFNPITNMHLRLFE 63 Query: 83 NLNKKLFTVVAW 94 L + Sbjct: 64 VARDHLHQTGRY 75 >3GZ3-A nrPDB Length = 354 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 8/24 (33%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV 46 G H+ G S +V + Sbjct: 18 GSHMASMTGGQQMGRGSMSLQVNL 41 >5W8O-A nrPDB Length = 363 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 92 VAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKK-VSLLGWSDGGITALIAAA 150 + D + +G FPA + + + A+ + +++G S GG AL Sbjct: 106 LHPDGKAWG------SRFPAVTVRDQVRADLAALNAMGIHQVAAVVGGSMGGARALEWVI 159 Query: 151 KYPSYIHKMVIWGANAYVTDE 171 +P + +I A T + Sbjct: 160 GHPETVRAGLILAVGARATAD 180 >2QS9-A nrPDB Length = 194 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 231 RVQCPALIVHGE-KDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFAD 280 + CP ++ G DP +P + + ++LH + H + F + Sbjct: 124 KANCPYIVQFGSTDDPFLPWKEQQEVADRL-ETKLHKFTDCGHFQNTEFHE 173 >2B61-A nrPDB Length = 377 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 42/115 (36%), Gaps = 12/115 (10%) Query: 107 RDFPADFFERDAKDAV----DLMKALKFKKV-SLLGWSDGGITALIAAAKYPSYIHKMVI 161 + + + F +D V L++ L + +++G S GG+ A A YP ++ +V Sbjct: 125 KPYGSQFPNIVVQDIVKVQKALLEHLGISHLKAIIGGSFGGMQANQWAIDYPDFMDNIVN 184 Query: 162 WGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQF 216 ++ Y + E +R G DY+ T I + Sbjct: 185 LCSSIYFSAEAIGFNHVMRQAVINDPNFN-------GGDYYEGTPPDQGLSIARM 232 >4IRN-A nrPDB Length = 416 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 11/34 (32%), Gaps = 1/34 (2%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQT 56 G H+ G A N Q+ +++ Sbjct: 18 GSHMASMTGGQQMGRGSEFDF-AWNSQQIQFRKK 50 >4B6G-A nrPDB Length = 283 Score = 32.8 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 131 KKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTR 190 K S++G S GG AL+ A + + + S++ G + + + + R Sbjct: 145 GKRSIMGHSMGGHGALVLALRNQERYQSVSAFSPILS----PSLVPWGEKAFTAYLGKDR 200 Query: 191 K 191 + Sbjct: 201 E 201 >1DT3-A nrPDB Length = 269 Score = 32.8 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 44/118 (37%), Gaps = 16/118 (13%) Query: 45 AVNGVQLH-YQQTGEGD----------HAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVA 93 + L+ ++ +G GD + +++L ++ L N + K + Sbjct: 46 KADATFLYSFEDSGVGDVTGFLALDNTNKLIVLSFRGSRSIENWIGNL-NFDLKEINDIC 104 Query: 94 WDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAK 151 RG+ R AD + +DAV + + +V G S GG A +A A Sbjct: 105 SGCRGHDGFTSSWRS-VADTLRQKVEDAVR--EHPDY-RVVFTGHSLGGALATVAGAD 158 >6QPR-A nrPDB Length = 361 Score = 32.8 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 21/69 (30%) Query: 111 ADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 + +D K KV++ G S GG TAL+ A + Y Sbjct: 208 GEVQNELVATVLDQFKQYPSYKVAVTGHSLGGATALLCALDLYQREEGLSSSNLFLYTQG 267 Query: 171 EDSMIYEGI 179 + + Sbjct: 268 QPRVGDPAF 276 >4NPN-A nrPDB Length = 102 Score = 32.8 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 4/29 (13%), Positives = 8/29 (27%), Gaps = 1/29 (3%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQL 51 G H+ G + + + L Sbjct: 1 GSHMASMTGGQQMGRGSEFTE-NNDHINL 28 >2RDU-A nrPDB Length = 387 Score = 32.8 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 20/151 (13%), Positives = 41/151 (27%), Gaps = 15/151 (9%) Query: 23 GIHVPRAGPAAAFGTSVT-SAKVAVNGVQLH-----------YQQTGEGDHAVLLLPGML 70 G H+ G + +N + H Y ++G D L Sbjct: 1 GSHMASMTGGQQMGRGSMLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAA 60 Query: 71 GSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKF 130 S + L+N+ + + R S P A + ++A + Sbjct: 61 FSRWKLYPRMLRNVAETDLSTSVLGQR---VSMPICVGATAMQRMAHVDGELATVRACQS 117 Query: 131 KKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161 ++ S + A P + + + Sbjct: 118 LGTGMMLSSWATSSIEEVAEAGPEALRWLQL 148 >4TGL-A nrPDB Length = 269 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 20/63 (31%) Query: 111 ADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 + +D K KV++ G S GG TAL+ A + Y Sbjct: 116 GEVQNELVATVLDQFKQYPSYKVAVTGHSLGGATALLCALDLYQREEGLSSSNLFLYTQG 175 Query: 171 EDS 173 + Sbjct: 176 QPR 178 >1ODT-C nrPDB Length = 318 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 41/273 (15%), Positives = 74/273 (27%), Gaps = 39/273 (14%) Query: 47 NGVQLH---YQQTG-------------EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFT 90 +GV+++ Y+ G EG H ++ + ++ N + Sbjct: 52 DGVKVYRLTYKSFGNARITGWYAVPDKEGPHPAIVKYHGYNASYDGEIHEMVNWALHGYA 111 Query: 91 VVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAA 150 RG S K L G + AL + Sbjct: 112 TFGMLVRGQQSSEDTSISPHGHALGWMTKGI------LDKDTYYYRGVYLDAVRALEVIS 165 Query: 151 KYPS----------YIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYG-Y 199 + + A A ++D +S + LE Y Sbjct: 166 SFDEVDETRIGVTGGAQGGGLTIAAAALSDIPKAAVADYPYLSNFERAIDVALEEPYLEI 225 Query: 200 DYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHV 259 + F R ++ K L +I +L RV+ P L+ G D + P + H+ Sbjct: 226 NSFFRRNGSPETEVQAMKTLSYFDIM-NLADRVKVPVLMSIGLIDKVTPPSTVFAAYNHL 284 Query: 260 K-GSRLHLMPEGKHNLHLRFADEFNKLAEDFLQ 291 + L + H + F F + Sbjct: 285 ETKKELKVYRYFGH----EYIPAFQTEKLAFFK 313 >3K3P-A nrPDB Length = 383 Score = 32.8 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 7/24 (29%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV 46 G H+ G S + V Sbjct: 18 GSHMASMTGGQQMGRGSMSKETLV 41 >1JFR-A nrPDB Length = 262 Score = 32.4 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 215 QFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRF-HADFIHKHVKGS--RLHL-MPEG 270 + G P ++ P L+V + D + P H+ ++ + GS + +L + Sbjct: 148 KAAIPLTGWNTDKTWPELRTPTLVVGADGDTVAPVATHSKPFYESLPGSLDKAYLELRGA 207 Query: 271 KHNLHLRFADEFNKLAEDFLQ 291 H K + +L+ Sbjct: 208 SHFTPNTSDTTIAKYSISWLK 228 >5CTQ-A nrPDB Length = 561 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 8/29 (27%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQL 51 G H+ G + G QL Sbjct: 18 GSHMASMTGGQQMGRGSEFENLYFQGNQL 46 >4HBK-A nrPDB Length = 344 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 5/29 (17%), Positives = 7/29 (24%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQL 51 G H+ G NG + Sbjct: 18 GSHMASMTGGQQMGRGSMEPLKMNNGRSI 46 >5ZBB-B nrPDB Length = 188 Score = 32.4 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 12/29 (41%), Gaps = 1/29 (3%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQL 51 G H+ G S V++ GV++ Sbjct: 18 GSHMASMTGGQQMGRGSMSV-VSLLGVKI 45 >5DWD-A nrPDB Length = 240 Score = 32.4 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 28/83 (33%), Gaps = 4/83 (4%) Query: 194 EALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHAD 253 + Y + + I F L + P L++HG+ D +VP ++ Sbjct: 140 QGAMMALYTGLRLPEPLKAIIAFSGLIVAPEKLEAEIASKPPVLLIHGDLDDVVPVIGSE 199 Query: 254 FIHKHV----KGSRLHLMPEGKH 272 + +RLH+ H Sbjct: 200 TALPKLIDLGIDARLHISQGSGH 222 Score = 28.2 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 18/46 (39%) Query: 126 KALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDE 171 L L+G+S G + AL + P + ++ + ++ Sbjct: 126 TGLGPADTILVGFSQGAMMALYTGLRLPEPLKAIIAFSGLIVAPEK 171 >4Y12-A nrPDB Length = 375 Score = 32.4 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 10/37 (27%), Gaps = 7/37 (18%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEG 59 G H+ G L++Q G G Sbjct: 18 GSHMASMTGGQQMGRGSEFE-------NLYFQGLGGG 47 >5LOW-E nrPDB Length = 82 Score = 32.4 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 4/21 (19%), Positives = 6/21 (28%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G A+ Sbjct: 1 GSHMASMTGGQQMGRGSEFAR 21 >5LOB-E nrPDB Length = 96 Score = 32.4 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 4/21 (19%), Positives = 6/21 (28%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G A+ Sbjct: 15 GSHMASMTGGQQMGRGSEFAR 35 >5JYK-A nrPDB Length = 566 Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 8/52 (15%), Positives = 12/52 (23%), Gaps = 14/52 (26%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVN--------------GVQLHYQQTGEGD 60 G H+ G + +LH+ T GD Sbjct: 18 GSHMASMTGGQQMGRGSEFELLNNESEAGNQRTSSPERSRSRLHHSDTKNGD 69 >5ILA-A nrPDB Length = 301 Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 8/52 (15%), Positives = 12/52 (23%), Gaps = 14/52 (26%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVN--------------GVQLHYQQTGEGD 60 G H+ G + +LH+ T GD Sbjct: 18 GSHMASMTGGQQMGRGSEFELLNNESEAGNQRTSSPERSRSRLHHSDTKNGD 69 >2B20-A nrPDB Length = 403 Score = 32.1 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 46/127 (36%), Gaps = 12/127 (9%) Query: 111 ADFFERDAKDAVDLMKAL-----KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165 ADF+ ++ + L+K + + + + G S GG++AL A +P ++ + Sbjct: 251 ADFWLAVQQELLPLVKVIAPFSDRADRTVVAGQSFGGLSALYAGLHWPERFGCVLSQSGS 310 Query: 166 AYVTDEDSM----IYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPD 221 + + E ++ +E R LEA R + Q + + Sbjct: 311 YWWPHRGGQQEGVLLEKLKAGEVSAEGLRIVLEAGIREPMIMRANQAL---YAQLHPIKE 367 Query: 222 GNICRHL 228 R + Sbjct: 368 SIFWRQV 374 >3RPL-B nrPDB Length = 379 Score = 32.1 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 11/94 (11%), Positives = 28/94 (29%), Gaps = 11/94 (11%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G + + + +++ + A + +G GE + Q+ Sbjct: 18 GSHMASMTGGQQMGRGSVDSTLGLEIIEVV-------EQAAIASAKWMGKGEKNTADQVA 70 Query: 83 NLN-KKLFTVVAWDPR---GYGHSRPPDRDFPAD 112 ++ + R G G + + Sbjct: 71 VEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGE 104 >3L87-A nrPDB Length = 238 Score = 32.1 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 5/20 (25%), Positives = 6/20 (30%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G SA Sbjct: 18 GSHMASMTGGQQMGRGSMSA 37 >4N8K-A nrPDB Length = 476 Score = 32.1 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 17/65 (26%), Gaps = 4/65 (6%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G + L+ ++ + AV + F + Sbjct: 18 GSHMASMTGGQQMGRGSEFMDIRA----LYDEKLTTPEEAVSSIASGSHLSMGMFAAEPP 73 Query: 83 NLNKK 87 L K Sbjct: 74 ALLKA 78 >4ZCK-A nrPDB Length = 332 Score = 32.1 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 8/26 (30%), Gaps = 1/26 (3%) Query: 23 GIHVPRAGPAAAFGTSVT-SAKVAVN 47 G H+ G T S VN Sbjct: 18 GSHMASMTGGQQMGRGSTVSMFFCVN 43 >1GPL-A nrPDB Length = 432 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 40/105 (38%), Gaps = 15/105 (14%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTV-----VAWDPRGYGHSRPPDRDFPADFFERDA 118 ++ G SGE + L ++ K +F V + D +G ++ + Sbjct: 74 FIIHGFTDSGENSW---LSDMCKNMFQVEKVNCICVDWKGGSKAQYSQASQNIRVVGAEV 130 Query: 119 KDAVDLMKA-LKF--KKVSLLGWSDGGITALIAAAKYPSYIHKMV 160 V ++ L + + V ++G S G T A + ++ +V Sbjct: 131 AYLVQVLSTSLNYAPENVHIIGHSLGAHT----AGEAGKRLNGLV 171 >5XCN-X nrPDB Length = 350 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 6/51 (11%), Positives = 12/51 (23%), Gaps = 8/51 (15%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSG 73 G H+ G + G+ ++ L +G Sbjct: 18 GSHMASMTGGQQMGRGSMAIYAD--------NSYSIGNTPLVRLKHFGHNG 60 >3RK6-A nrPDB Length = 234 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 7/23 (30%), Gaps = 1/23 (4%) Query: 23 GIHVPRAGPAAAFGTSVT-SAKV 44 G H+ G T S V Sbjct: 1 GSHMASMTGGQQMGRGSTLSEYV 23 >4QPJ-A nrPDB Length = 243 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 17/53 (32%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGET 75 G H+ G S V ++ + L H ++ G + +G Sbjct: 18 GSHMASMTGGQQMGRGSMSLPVTLSALDLGALLCSRICHDIISPIGAINNGLE 70 >6AVW-A nrPDB Length = 230 Score = 31.7 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 22/70 (31%), Gaps = 2/70 (2%) Query: 123 DLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDE--DSMIYEGIR 180 ++ + + V + G S GG L + YP + + T E + Sbjct: 92 EIAEGTNPENVFICGLSQGGALTLASVLLYPKTLGGGAVLSGWVPFTSSIISQFPEEAKK 151 Query: 181 DVSKWSERTR 190 WS T Sbjct: 152 TPILWSHGTD 161 >5K52-A nrPDB Length = 265 Score = 31.7 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 34/118 (28%), Gaps = 25/118 (21%) Query: 18 SALKP-GIHVPRAGPAAAFGTSVTS-------------------AKVAVNGVQLHYQQTG 57 S L P G H+ G A +N + + + Sbjct: 8 SGLVPRGSHMASMTGGQQMGRGSEFMPQLEATAAIDYQSETYKDAYSRINAIVIEGEDEA 67 Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFE 115 ++ L S E +++ +KK FT G + PD DF FF Sbjct: 68 ANNYVRLAELMPEQSEELASLAKMEARHKKGFTAC-----GKNLNVTPDMDFAKKFFS 120 >5A2B-A nrPDB Length = 497 Score = 31.7 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 3/31 (9%), Positives = 11/31 (35%), Gaps = 1/31 (3%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHY 53 G H+ G + + + ++++ Sbjct: 18 GSHMASMTGGQQMGRGSKTERTWQDE-RIYF 47 >4X9L-A nrPDB Length = 250 Score = 31.7 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 9/73 (12%), Positives = 23/73 (31%), Gaps = 6/73 (8%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G +++ Q E + + L+ S + F +L Sbjct: 18 GSHMASMTGGQQMGRGSMASETETFAFQ------AEINQLLSLIINTFYSNKEIFLRELI 71 Query: 83 NLNKKLFTVVAWD 95 + + + ++ Sbjct: 72 SNSSDALDKIRFE 84 >1RP1-A nrPDB Length = 450 Score = 31.7 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 23/150 (15%), Positives = 46/150 (30%), Gaps = 30/150 (20%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTV-----VAWDPRGYGHSRPPDRDFPADFFERDA 118 ++ G + GE ++ L ++ K +F V + D + A+ Sbjct: 74 FIIHGFIDKGEENW---LLDMCKNMFKVEEVNCICVD---WKKGSQTSYTQAANNVRVVG 127 Query: 119 KDAVDLMKALKF------KKVSLLGWSDGGITALIAAAKYP--SYIHKMVIWGANAYVTD 170 ++ L +V L+G S G A A ++ P I + D Sbjct: 128 AQVAQMLSMLSANYSYSPSQVQLIGHSLGAHVAGEAGSRTPGLGRITGL----------D 177 Query: 171 EDSMIYEGIRDVSKWSERTRKPLEALYGYD 200 ++G + + T + D Sbjct: 178 PVEASFQGTPEEVRLD-PTDADFVDVIHTD 206 >5K53-A nrPDB Length = 262 Score = 31.7 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 7/25 (28%), Gaps = 1/25 (4%) Query: 18 SALKP-GIHVPRAGPAAAFGTSVTS 41 S L P G H+ G Sbjct: 8 SGLVPRGSHMASMTGGQQMGRGSEF 32 >4WZH-A nrPDB Length = 347 Score = 31.7 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 6/26 (23%), Positives = 9/26 (34%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNG 48 G H+ G S +V + G Sbjct: 18 GSHMASMTGGGQMGRGSMSLQVGILG 43 >3ENV-A nrPDB Length = 235 Score = 31.7 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 21/68 (30%), Gaps = 9/68 (13%) Query: 23 GIHVPRAGPAAAFGTSVTSA---KVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGP 79 G H+ G + K A L Y + G ++ GS F Sbjct: 1 GSHMASMTGGQQMGRGSMTQDEMKKAAGWAALKYVEKGS------IVGVGTGSTVNHFID 54 Query: 80 QLKNLNKK 87 L ++++ Sbjct: 55 ALGTMSEE 62 >3L8A-A nrPDB Length = 421 Score = 31.7 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 4/21 (19%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSMGRY 38 >2QJ0-A nrPDB Length = 982 Score = 31.7 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 3/20 (15%), Positives = 4/20 (20%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGSEFR 20 >3L9C-A nrPDB Length = 259 Score = 31.7 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 6/24 (25%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV 46 G H+ G V V Sbjct: 18 GSHMASMTGGQQMGRGSMKIVVPV 41 >3PSP-A nrPDB Length = 425 Score = 31.7 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 3/22 (13%), Positives = 7/22 (31%) Query: 23 GIHVPRAGPAAAFGTSVTSAKV 44 G H+ G + ++ Sbjct: 18 GSHMASMTGGQQMGRGSSPYEI 39 >3LEH-A nrPDB Length = 425 Score = 31.7 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 4/28 (14%), Positives = 6/28 (21%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQ 50 G H+ G + G Sbjct: 18 GSHMASMTGGQQMGRGSMRIGIDKIGFT 45 >3CNC-A nrPDB Length = 220 Score = 31.7 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 4/20 (20%), Positives = 6/20 (30%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G S+ Sbjct: 1 GSHMASMTGGQQMGRGSDSS 20 >1BU8-A nrPDB Length = 452 Score = 31.3 bits (69), Expect = 0.45, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 43/122 (35%), Gaps = 13/122 (10%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTV-----VAWDPRGYGHSRPPDRDFPADFFERDA 118 ++ G + GE + L ++ KK+F V + D R + + + Sbjct: 74 FIVHGFIDKGEDGW---LLDMCKKMFQVEKVNCICVDWRRGSRTEYTQASYNTRVVGAEI 130 Query: 119 KDAVDLMKA-LKF--KKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMI 175 V ++ + + + V L+G S G A + ++ + I G + + Sbjct: 131 AFLVQVLSTEMGYSPENVHLIGHSLGAHVVGEAGRRLEGHVGR--ITGLDPAEPCFQGLP 188 Query: 176 YE 177 E Sbjct: 189 EE 190 >4WTS-A nrPDB Length = 298 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 7/28 (25%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQ 50 G H+ G + GV Sbjct: 18 GSHMASMTGGQQMGRGSQTFYGINYGVN 45 >4HG5-A nrPDB Length = 341 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 4/23 (17%), Positives = 8/23 (34%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVA 45 G H+ G ++K+ Sbjct: 18 GSHMASMTGGQQMGRGSMTSKLK 40 >6CHV-A nrPDB Length = 121 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 4/21 (19%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGSMRQF 21 >3W9B-A nrPDB Length = 328 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 38/110 (34%), Gaps = 10/110 (9%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKK-LFTVVAWDPRGYGHSRPPDRDFPADFFERDAK 119 +LL+PG +G F L+ + +T P + + E Sbjct: 39 KPILLVPGTGTTGPQSFDSNWIPLSTQLGYTPCWISPPPFMLNDTQVNT------EYMVN 92 Query: 120 DAVDLMKALKFKKVSLLGWSDGGITALIAAAKYP---SYIHKMVIWGANA 166 L K+ +L WS GG+ A +P S + +++ + + Sbjct: 93 AITALYAGSGNNKLPVLTWSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDY 142 >3CN7-A nrPDB Length = 226 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 30/80 (37%), Gaps = 6/80 (7%) Query: 101 HSRPPDRDFPADFFERDAKDAVDLMK-----ALKFKKVSLLGWSDGGITALIAAA-KYPS 154 + P R D A + L+ + +++ L G+S GG L A +Y Sbjct: 81 LAFSPARAIDEDQLNASADQVIALIDEQRAKGIAAERIILAGFSQGGAVVLHTAFRRYAQ 140 Query: 155 YIHKMVIWGANAYVTDEDSM 174 + ++ A D+ ++ Sbjct: 141 PLGGVLALSTYAPTFDDLAL 160 >6ERD-A nrPDB Length = 211 Score = 31.3 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 7/24 (29%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV 46 G H+ G S+ V Sbjct: 18 GSHMASMTGGQQMGRDPNSSSVDK 41 >3LNB-A nrPDB Length = 309 Score = 31.3 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 7/23 (30%), Gaps = 1/23 (4%) Query: 18 SALKP-GIHVPRAGPAAAFGTSV 39 S L P G H+ G Sbjct: 8 SGLVPRGSHMASMTGGQQMGRGS 30 >4GAX-A nrPDB Length = 563 Score = 31.3 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 5/19 (26%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G S Sbjct: 1 GSHMASMTGGQQMGRGSMS 19 >3LBE-A nrPDB Length = 163 Score = 31.3 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 5/19 (26%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G S Sbjct: 18 GSHMASMTGGQQMGRGSMS 36 >4JEK-A nrPDB Length = 453 Score = 31.3 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 4/42 (9%), Positives = 11/42 (26%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVL 64 G H+ G ++ + + + D + Sbjct: 18 GSHMASMTGGQQMGRGSEFMTLSPEKQHVRPRDAADNDPVAV 59 >6CF1-A nrPDB Length = 138 Score = 31.3 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 4/21 (19%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSMRQF 38 >3WNW-A nrPDB Length = 212 Score = 31.3 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 13/37 (35%), Gaps = 1/37 (2%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEG 59 G H+ G + + + V+ +Y Q E Sbjct: 1 GSHMASMTGGQQMGRGSMTT-ASPSQVRQNYHQDAEA 36 >5LOW-D nrPDB Length = 95 Score = 30.9 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 5/21 (23%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G + Sbjct: 1 GSHMASMTGGQQMGRGSEFMR 21 >5HXY-A nrPDB Length = 317 Score = 30.9 bits (68), Expect = 0.60, Method: Composition-based stats. Identities = 4/23 (17%), Positives = 6/23 (26%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVA 45 G H+ G A+ Sbjct: 18 GSHMASMTGGQQMGRGSMPAETN 40 >2UXN-B nrPDB Length = 235 Score = 30.9 bits (68), Expect = 0.60, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 5/21 (23%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G + Sbjct: 18 GSHMASMTGGQQMGRGSEFGR 38 >2BMB-A nrPDB Length = 545 Score = 30.9 bits (68), Expect = 0.61, Method: Composition-based stats. Identities = 4/29 (13%), Positives = 6/29 (20%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQL 51 G H+ G G + Sbjct: 1 GSHMASMTGGQQMGRGSWKRAFLAFGSNI 29 >6O09-C nrPDB Length = 312 Score = 30.9 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 15/124 (12%), Positives = 35/124 (28%), Gaps = 14/124 (11%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLK 82 G H+ G + L++ +G + L+ G L +K Sbjct: 18 GSHMASMTGGQQMGRGSMGHHHHHHE-NLYF----QGMLELRLVQGSLLKKV---LESIK 69 Query: 83 NLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG 142 +L +D G S + + + + + +G + G Sbjct: 70 DLVNDA----NFDCSSTGFSLQAMDSSHVALVSLLLRS--EGFEHYRCDRNLSMGMNLGN 123 Query: 143 ITAL 146 ++ + Sbjct: 124 MSKM 127 >6GII-A nrPDB Length = 479 Score = 30.9 bits (68), Expect = 0.64, Method: Composition-based stats. Identities = 3/23 (13%), Positives = 6/23 (26%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVA 45 G H+ G ++ Sbjct: 18 GSHMASMTGGQQMGRGSMETELK 40 >4MQM-A nrPDB Length = 304 Score = 30.9 bits (68), Expect = 0.64, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 44/124 (35%), Gaps = 14/124 (11%) Query: 48 GVQLHYQQTGEGDHAVLLLPGMLGSGETD-FGPQLKNLNKKLFTVVAWDPRGYGHSR--- 103 G + Q G G HAV LL G+ + + + + + ++ G S Sbjct: 21 GRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYT 80 Query: 104 ---PPDRD----FPADFFERDAKDAVDLMKALKFKKVS---LLGWSDGGITALIAAAKYP 153 P + + + ++ ++A K + +G S G +ALI AA YP Sbjct: 81 DWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYP 140 Query: 154 SYIH 157 Sbjct: 141 QQFP 144 >2YH2-A nrPDB Length = 313 Score = 30.9 bits (68), Expect = 0.64, Method: Composition-based stats. Identities = 40/207 (19%), Positives = 65/207 (31%), Gaps = 22/207 (10%) Query: 48 GVQLHYQQTGEGDHAVLLLPGML--GSGETDFGPQLKNLNK-KLFTVVAWDPRGYGHSRP 104 +++ + GE AV+ G + L VV+ D R + Sbjct: 64 RARVYRPRDGERLPAVVYYHGGGFVLGSVETHDHVCRRLANLSGAVVVSVDYR---LAPE 120 Query: 105 PDRDFPADFFERDAKDAVDLMKALKFK--KVSLLGWSDGGITALIAAAKYPSYIHKMV-- 160 + AK D L K+++ G S GG A + A V Sbjct: 121 HKFPAAVEDAYDAAKWVADNYDKLGVDNGKIAVAGDSAGGNLAAVTAIMARDRGESFVKY 180 Query: 161 -IWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHL 219 + A + ++ T L A +G YF+ K D + + Sbjct: 181 QVLIYPAVNLTGSPTVSRVEYSGPEYVILT-ADLMAWFGRQYFS----KPQDALSPYASP 235 Query: 220 PDGNICRHLLPRVQCPALIVHGEKDPL 246 ++ LP PAL++ E DPL Sbjct: 236 IFADLSN--LP----PALVITAEYDPL 256 >2NT8-A nrPDB Length = 223 Score = 30.9 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 5/26 (19%), Positives = 7/26 (26%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNG 48 G H+ G + NG Sbjct: 18 GSHMASMTGGQQMGRDRSVKIYTKNG 43 >6BJE-A nrPDB Length = 222 Score = 30.9 bits (68), Expect = 0.66, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 32/86 (37%), Gaps = 6/86 (6%) Query: 104 PPDRDFPADFFERDAKDAVDLMKA-----LKFKKVSLLGWSDGGITALIAAAKYPSYIHK 158 PD ++ A++ L++ + ++ L G+S GG +L A P + Sbjct: 73 SPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAG 132 Query: 159 MVIWGANAYVTDEDSMIYEG-IRDVS 183 +V + G +D++ Sbjct: 133 IVALSCWLPLHRAFPQAANGSAKDLA 158 >5C2O-A nrPDB Length = 184 Score = 30.9 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 3/23 (13%), Positives = 8/23 (34%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVA 45 G H+ G + +++ Sbjct: 18 GSHMASMTGGQQMGRGSMTNRLS 40 >3L8R-A nrPDB Length = 120 Score = 30.9 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 6/21 (28%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G + + Sbjct: 1 GSHMASMTGGQQMGRGSMNTE 21 >3ZF4-A nrPDB Length = 204 Score = 30.9 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 4/24 (16%), Positives = 7/24 (29%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAV 46 G H+ G + + V Sbjct: 18 GSHMASMTGGQQMGRGSMTNTLQV 41 >5U50-A nrPDB Length = 265 Score = 30.9 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 3/20 (15%), Positives = 4/20 (20%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEFE 37 >3OXG-A nrPDB Length = 464 Score = 30.9 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 3/21 (14%), Positives = 5/21 (23%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G + Sbjct: 18 GSHMASMTGGQQMGRGSEFME 38 >5I5F-A nrPDB Length = 586 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 32/221 (14%), Positives = 63/221 (28%), Gaps = 27/221 (12%) Query: 50 QLHYQQTGEGDHAVLLLPGMLG--------SGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 LHY+ G G + +L+ L F Q + + + + D +G Sbjct: 250 NLHYRDMGTGQNVLLITVDGLNYSRFEKQMPELATFAEQNIDFTRHMSSGNTTDNGIFGL 309 Query: 102 SRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI 161 + L+ AL + L +S G + P Y ++ Sbjct: 310 FYGISPGYMDGVLSTRTP--AALITALNQQGYQLGLFSSDGFAS-------PLYRQALLS 360 Query: 162 WG--ANAYVTDEDSMIYEGIRDVSKWSERTRKPLE--ALYGYDYFARTCEKWVDGIRQFK 217 A + + I + ++++ + + G + + +V Sbjct: 361 DFSMPAAQTQSDAQTASQWIDWLGRYAQEDNRWFSWISFNGTNIDDSNQKNFVKRYASAA 420 Query: 218 HLPDGNICRHLLPRVQCP------ALIVHGEKDPLVPRFHA 252 D I R L + +I G PL P + Sbjct: 421 SDVDAQINRVLNALREAGKFDNTVVIITAGRGIPLTPEENR 461 >6MSO-A nrPDB Length = 585 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >6MSN-A nrPDB Length = 604 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >5GV1-A nrPDB Length = 322 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >3WG8-A nrPDB Length = 227 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >3NC3-A nrPDB Length = 441 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >3L7R-A nrPDB Length = 779 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 3/20 (15%), Positives = 5/20 (25%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G + Sbjct: 18 GSHMASMTGGQQMGRGSMTK 37 >5L6F-A nrPDB Length = 497 Score = 30.9 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 38/232 (16%), Positives = 67/232 (28%), Gaps = 21/232 (9%) Query: 14 RLLLSALKPGIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSG 73 R+ L P H+ P A G T H G G L G S Sbjct: 114 RMYNVTLDPETHIATVQPGARLGHIATVLYEEGKRAFSHGTCPGVGVGGHSLHGGFGFSS 173 Query: 74 ET-----DFGPQLKNLNKKLFTV---------VAWDPRGYGHSRPPDRDFPADFFERDAK 119 + D+ + V + W RG G + F F Sbjct: 174 HSHGLAVDWITSADVVLANGSLVTASETENPDLFWALRGAGSNFGIVASFRFKTFAAPPN 233 Query: 120 DAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGI 179 + L + S + G + + P ++ V+ A + +Y G Sbjct: 234 VTSYEIN-LPWTNSSNVVKGWGALQEWLLNGGMPEEMNMRVLGNA---FQTQLQGLYHG- 288 Query: 180 RDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPR 231 + + +PL AL + + W++G R + + + +I + Sbjct: 289 --NASALKTAIQPLLALLDANLSSVQEHDWMEGFRHYAYSGEIDITDPGYDQ 338 >3SR7-A nrPDB Length = 365 Score = 30.9 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 16/49 (32%), Gaps = 1/49 (2%) Query: 23 GIHVPRAGPAAAFGT-SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGML 70 G H+ G S+T+ K L Y+ + L+ L Sbjct: 18 GSHMASMTGGQQMGRGSMTNRKDDHIKYALDYRSPYNSFDDIELIHHSL 66 >6QGB-A nrPDB Length = 596 Score = 30.5 bits (67), Expect = 0.78, Method: Composition-based stats. Identities = 24/138 (17%), Positives = 49/138 (35%), Gaps = 27/138 (19%) Query: 52 HYQQTGEG-DHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH--SRPPD-- 106 + + G G + ++ G +G G Q+ + + F +A D G+ + + PD Sbjct: 118 FFMEGGSGTNGSLSAATGSIGGG------QIASALSRNFATIATDG-GHDNAVNDNPDAL 170 Query: 107 --------------RDF-PADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAK 151 + D + K AV K +G S+GG ++ + + Sbjct: 171 GTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQR 230 Query: 152 YPSYIHKMVIWGANAYVT 169 +PS+ +V + Sbjct: 231 FPSHYDGIVAGAPGYQLP 248 >5Z6H-A nrPDB Length = 563 Score = 30.5 bits (67), Expect = 0.78, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >5BV7-A nrPDB Length = 422 Score = 30.5 bits (67), Expect = 0.80, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 36/119 (30%), Gaps = 20/119 (16%) Query: 76 DFGPQLKNLNKKLF------TVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALK 129 ++NL + +D R + +++ + A ++ A Sbjct: 120 YLHTLVQNLVNNGYVRDETVRAAPYDWRL-------EPGQQEEYYRKLAGLVEEMHAAYG 172 Query: 130 FKKVSLLGWSDGGITALIAAAKYPSY-----IHKMVIWGANAYVTDEDSMIYEGIRDVS 183 K V L+G S G + L + P I + GA + M+ D Sbjct: 173 -KPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGA-PWGGSIKPMLVLASGDNQ 229 >4XBS-A nrPDB Length = 265 Score = 30.5 bits (67), Expect = 0.82, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >1FJ2-A nrPDB Length = 232 Score = 30.5 bits (67), Expect = 0.82, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 25/80 (31%), Gaps = 5/80 (6%) Query: 104 PPDRDFPADFFERDAKDAVDLMKA-----LKFKKVSLLGWSDGGITALIAAAKYPSYIHK 158 PD ++ A++ L+ + ++ L G+S GG +L A + Sbjct: 81 SPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAG 140 Query: 159 MVIWGANAYVTDEDSMIYEG 178 + + G Sbjct: 141 VTALSCWLPLRASFPQGPIG 160 >3QAU-A nrPDB Length = 458 Score = 30.5 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 10/28 (35%), Gaps = 2/28 (7%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQ 50 G H+ G S K++ NG Sbjct: 18 GSHMASMTGGQQMGRG--SMKISWNGFS 43 >2QM9-A nrPDB Length = 155 Score = 30.5 bits (67), Expect = 0.86, Method: Composition-based stats. Identities = 4/20 (20%), Positives = 6/20 (30%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G +S Sbjct: 1 GSHMASMTGGNNMGRGSSSK 20 >4J0Q-A nrPDB Length = 433 Score = 30.5 bits (67), Expect = 0.86, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >2PVS-A nrPDB Length = 452 Score = 30.5 bits (67), Expect = 0.88, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 11/93 (11%) Query: 64 LLLPGMLGSGETDFGPQL--KNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDA 121 ++ G L E + + K + + D R H + Sbjct: 74 FIIHGFLDKAEDSWPSDMCKKMFEVEKVNCICVDWR---HGSRAMYTQAVQNIRVVGAET 130 Query: 122 VDLMKALK------FKKVSLLGWSDGGITALIA 148 L++AL + V ++G S G TA A Sbjct: 131 AFLIQALSTQLGYSLEDVHVIGHSLGAHTAAEA 163 >6MLK-A nrPDB Length = 300 Score = 30.5 bits (67), Expect = 0.89, Method: Composition-based stats. Identities = 37/219 (16%), Positives = 65/219 (29%), Gaps = 22/219 (10%) Query: 56 TGEGDHAVLLLPGMLG-SGETDFGPQLKNLNKKLFT-VVAWDPRGYGHSRPPDRDFPADF 113 G G+ V+ G SG +F L + V A GY P+ Sbjct: 63 DGPGEVTVICCAGTAAISGPHEFTRLAGAL--RGIAPVRAVPQPGY----EEGEPLPSSM 116 Query: 114 FERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAK-----YPSYIHKMVIWGANAYV 168 A A +++ K + G S G + A A + +P ++ + Sbjct: 117 AAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPPGHQ 176 Query: 169 TDEDSMIYEGIRDVSKWS--ERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDG---- 222 ++ + E + L AL YD G+ Sbjct: 177 DAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAGEPMGP 236 Query: 223 --NICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHV 259 + + + V G+ +V + HAD I +H+ Sbjct: 237 WPDDSWKPTWPFEHDTVAVPGDHFTMV-QEHADAIARHI 274 >1ETH-A nrPDB Length = 448 Score = 30.5 bits (67), Expect = 0.91, Method: Composition-based stats. Identities = 22/142 (15%), Positives = 49/142 (34%), Gaps = 13/142 (9%) Query: 64 LLLPGMLGSGETDFGPQL-KNLNK-KLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDA 121 ++ G + GE D+ + KNL K + + D +G + + Sbjct: 73 FIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYF 132 Query: 122 VDLMKA-LKFK--KVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEG 178 V+++K+ L + V ++G S G AA + + + D ++G Sbjct: 133 VEVLKSSLGYSPSNVHVIGHSLGSH----AAGEAGRRTNGTIERITGL---DPAEPCFQG 185 Query: 179 IRDVSKWSERTRKPLEALYGYD 200 ++ + + + D Sbjct: 186 TPELVRLD-PSDAKFVDVIHTD 206 >5GVX-A nrPDB Length = 430 Score = 30.5 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 4/22 (18%), Positives = 5/22 (22%) Query: 23 GIHVPRAGPAAAFGTSVTSAKV 44 G H+ G V Sbjct: 18 GSHMASMTGGQQMGRGSEFELV 39 >4H27-A nrPDB Length = 364 Score = 30.5 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >5D3Z-A nrPDB Length = 269 Score = 30.5 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 37/219 (16%), Positives = 65/219 (29%), Gaps = 22/219 (10%) Query: 56 TGEGDHAVLLLPGMLG-SGETDFGPQLKNLNKKLFT-VVAWDPRGYGHSRPPDRDFPADF 113 G G+ V+ G SG +F L + V A GY P+ Sbjct: 49 DGPGEVTVICCAGTAAISGPHEFTRLAGAL--RGIAPVRAVPQPGY----EEGEPLPSSM 102 Query: 114 FERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAK-----YPSYIHKMVIWGANAYV 168 A A +++ K + G S G + A A + +P ++ + Sbjct: 103 AAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPPGHQ 162 Query: 169 TDEDSMIYEGIRDVSKWS--ERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDG---- 222 ++ + E + L AL YD G+ Sbjct: 163 DAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAGEPMGP 222 Query: 223 --NICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHV 259 + + + V G+ +V + HAD I +H+ Sbjct: 223 WPDDSWKPTWPFEHDTVAVPGDHFTMV-QEHADAIARHI 260 >4M03-A nrPDB Length = 210 Score = 30.5 bits (67), Expect = 0.98, Method: Composition-based stats. Identities = 7/43 (16%), Positives = 14/43 (32%), Gaps = 4/43 (9%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLL 65 G H+ G V V + + G+ + ++L Sbjct: 18 GSHMASMTGGQQMGRGSAPT-VTVGNQTI---EVGKTMNPIVL 56 >5J32-A nrPDB Length = 403 Score = 30.5 bits (67), Expect = 0.99, Method: Composition-based stats. Identities = 4/21 (19%), Positives = 5/21 (23%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G K Sbjct: 18 GSHMASMTGGQQMGRGSEFGK 38 >6ECE-A nrPDB Length = 303 Score = 30.1 bits (66), Expect = 1.00, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 34/116 (29%), Gaps = 10/116 (8%) Query: 59 GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVA-WDPRGYGHSRPPDRDFPADFFERD 117 GD ++ G + ++L K F + + G G P + + Sbjct: 36 GDGPGIVFAPPAGGTVLGYIELARHL--KGFGEIHGVEAPGLGAGETPVYPSFEEMVQFC 93 Query: 118 AKDAVDLMKALKFKKVSLLGWSDGGITALIAA---AKYPSYIHKMVIWGANAYVTD 170 + A + V + G + GG A A ++I + D Sbjct: 94 SDSAAGVAG----DGVYIGGHALGGHIAFYLATMLLDRGIRPKGLIILDTPPRLGD 145 >5XTZ-A nrPDB Length = 163 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGS 17 >5XTP-A nrPDB Length = 293 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >5JZV-A nrPDB Length = 206 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >5JRE-A nrPDB Length = 219 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >5C1S-A nrPDB Length = 391 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >4M46-A nrPDB Length = 581 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >4M00-A nrPDB Length = 541 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >4IG7-A nrPDB Length = 343 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >4ETM-A nrPDB Length = 173 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGS 17 >4ABN-A nrPDB Length = 474 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >3VTW-A nrPDB Length = 149 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGS 17 >3OIX-A nrPDB Length = 345 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >3L9D-A nrPDB Length = 255 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >3CZC-A nrPDB Length = 110 Score = 30.1 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGS 17 >4EGS-A nrPDB Length = 180 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >2DGA-A nrPDB Length = 565 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 31/97 (31%), Gaps = 2/97 (2%) Query: 137 GWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEAL 196 G G IT YP + +++ Y + GI DV E PL+ Sbjct: 413 GNDIGPITGTYWIYMYPKGLTDLLLIMKEKYGNPPVFITENGIADVEG-DESMPDPLDDW 471 Query: 197 YGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQ 233 DY R D I Q G+ L+ + Sbjct: 472 KRLDYLQRHISAVKDAIDQ-GADVRGHFTWGLIDNFE 507 >3DEZ-A nrPDB Length = 243 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >6GI5-A nrPDB Length = 282 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 30/168 (17%), Positives = 47/168 (27%), Gaps = 37/168 (22%) Query: 40 TSAKVAVNGV--QLHYQQT---------GEGDHAVLLLPGMLGSGETDFGPQ-------L 81 + V ++ V Q HY+ G V +L G G D Sbjct: 24 RFSAVDLDSVDGQRHYRLWLGRPLQAPPAAGYPVVWMLDGNAAVGALDESTLRRLADGDA 83 Query: 82 KNLNKKLFTV-VAWDPRGYGHSRPPDRDFPADFFERD-------AKDAVDLMK------- 126 L + + D G P AD + A +DL++ Sbjct: 84 PLLVAIGYRTPLRIDRAGRTFDYTPASPGQADQRDPLNGLPSGGADAFLDLLRDGMRPAV 143 Query: 127 ----ALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 170 L + +L G S GG+ L A P + + + D Sbjct: 144 AAQAPLDTARQTLWGHSYGGLLVLHALFTRPGEFARYAAASPSLWWRD 191 >3H76-A nrPDB Length = 359 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 4/25 (16%), Positives = 6/25 (24%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVN 47 G H+ G + N Sbjct: 1 GSHMASMTGGQQMGRGSENLYFQGN 25 >2LEC-A nrPDB Length = 135 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 5/19 (26%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G S Sbjct: 18 GSHMASMTGGQQMGRGSMS 36 >4OTK-A nrPDB Length = 318 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >4U5I-A nrPDB Length = 403 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 5/37 (13%), Positives = 10/37 (27%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQQTGEG 59 G H+ G + + + + G G Sbjct: 18 GSHMASMTGGQQMGRIEGREFSSPEALAAYREAIGAG 54 >2QUB-A nrPDB Length = 615 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 47/140 (33%), Gaps = 15/140 (10%) Query: 16 LLSALKPGIHVPRAGPAAAFGTSV--TSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSG 73 ++SA + G +G + T+A+ V G Y G + G G Sbjct: 93 VISATQLGYAGKTDARGTYYGETAGYTTAQAEVLG---KYDSEGNLTAIGISFRGTSGPR 149 Query: 74 ETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKF--K 131 E+ G + ++ L G+G + + F D +A + Sbjct: 150 ESLIGDTIGDVINDLLA-------GFG-PKGYADGYTLKAFGNLLGDVAKFAQAHGLSGE 201 Query: 132 KVSLLGWSDGGITALIAAAK 151 V + G S GG+ AA+ Sbjct: 202 DVVVSGHSLGGLAVNSMAAQ 221 >4ETN-A nrPDB Length = 184 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >4KML-A nrPDB Length = 241 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 3/20 (15%), Positives = 4/20 (20%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGKRPK 37 >5KRE-A nrPDB Length = 239 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 102 SRPPDRDFPADFFERDAKDAVD--LMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKM 159 + P+ D + D +D + +K ++ + G+S GG A+ A + + + Sbjct: 87 NDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAMHLAYRNHQDVAGV 146 Query: 160 VIWGA 164 + Sbjct: 147 FALSS 151 >3NIB-A nrPDB Length = 309 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >6G21-A nrPDB Length = 507 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 37/125 (29%), Gaps = 12/125 (9%) Query: 64 LLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPA---DFFERDAKD 120 L G G L + F V + G S P P DF R Sbjct: 84 FLSTGNGGLSGCIQYYDLAYTSGLGFATVGANSGHNGTSGEPFYHHPEVLEDFVHRSVHT 143 Query: 121 AVDLMKAL-------KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDS 173 V + K L FKK LG S GG + KYP+ +V + Sbjct: 144 GVVVGKQLTKLFYEEGFKKSYYLGCSTGGRQGFKSVQKYPNDFDGVVA--GAPAFNMINL 201 Query: 174 MIYEG 178 M + Sbjct: 202 MSWSA 206 >2BDW-A nrPDB Length = 362 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 20/128 (15%), Positives = 41/128 (32%), Gaps = 23/128 (17%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNGVQLHYQ---QTGEGDHAVLLLPGMLGSGETDFGP 79 G H+ G A +Y + G+G +V+ +G +F Sbjct: 1 GPHMASMTGGQQMGRGSEFMMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGL-EFAA 59 Query: 80 QLKN---LNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLL 136 ++ N L+ + F + + R + P+ V L +++ + L Sbjct: 60 KIINTKKLSARDFQKLEREARICRKLQHPN--------------IVRLHDSIQEESFHYL 105 Query: 137 GWSD--GG 142 + GG Sbjct: 106 VFDLVTGG 113 >4QPJ-C nrPDB Length = 152 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >3QLL-A nrPDB Length = 316 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >1KNW-A nrPDB Length = 425 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 36/230 (15%), Positives = 60/230 (26%), Gaps = 18/230 (7%) Query: 69 MLGSGETDFGPQLKNLNKKLFTV-VAWDP-RGYGHSRPPDRDFPADFFERDAKDAVDLMK 126 + +G D QL V + +P G+GHS+ + D + Sbjct: 118 PVNAGSVDMLDQLGQ-VSPGHRVWLRVNPGFGHGHSQKTNTGGENSKHGIWYTDLPAALD 176 Query: 127 ALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWS 186 ++ + L+G + + A + GA E + I S Sbjct: 177 VIQRHHLQLVGIHMHIGSGVDYAHLEQ-------VCGAMVRQVIEFGQDLQAISAGGGLS 229 Query: 187 ERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVH------ 240 ++ EA+ Y+ R H I Q LI Sbjct: 230 VPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQ 289 Query: 241 --GEKDPLVPRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEFNKLAED 288 LV D + + GS H+ L A + Sbjct: 290 MGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVETVVAG 339 >4R1D-A nrPDB Length = 569 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 5/62 (8%) Query: 126 KALKFKKVSLLGWSDGGITALIAAAKYP-SYIHKMV----IWGANAYVTDEDSMIYEGIR 180 + ++ KV L+ S GG+ A + + +V ++ + YEGI Sbjct: 243 EQMRRMKVILVTHSMGGLVARALTQLHGYERVLGVVHGVQPATGSSTIYHHMRCGYEGIA 302 Query: 181 DV 182 V Sbjct: 303 QV 304 >5LZ5-A nrPDB Length = 388 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 16/28 (57%) Query: 120 DAVDLMKALKFKKVSLLGWSDGGITALI 147 D L ++ +K++++G S GG T + Sbjct: 209 DMEQLKDSIDREKIAVIGHSFGGATVIQ 236 >3UL6-A nrPDB Length = 139 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 4/20 (20%), Positives = 6/20 (30%) Query: 23 GIHVPRAGPAAAFGTSVTSA 42 G H+ G + A Sbjct: 18 GSHMASMTGGQQMGRGMAEA 37 >5EX6-C nrPDB Length = 434 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 4/19 (21%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGSEF 36 >3GA7-A nrPDB Length = 326 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 42/231 (18%), Positives = 75/231 (32%), Gaps = 47/231 (20%) Query: 65 LLPGMLGSGETDFGPQLKNLNKK--LFTVVAWDPRGYGHSRPPDRDFPA---------DF 113 L G G D ++ L + TV+ D +S P +P + Sbjct: 93 LHGGGFILGNLDTHDRIMRLLARYTGCTVIGID-----YSLSPQARYPQAIEETVAVCSY 147 Query: 114 FERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSY------IHKMVIWGANAY 167 F + A + +L +K+ G S G + AL +A + +++W Sbjct: 148 FSQHADEY-----SLNVEKIGFAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYG 202 Query: 168 VTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRH 227 + D S G W TR+ L+ Y D + L + ++ R Sbjct: 203 LQDSVSRRLFG----GAWDGLTREDLDM-----YEKAYLRNDEDRESPWYCLFNNDLTRD 253 Query: 228 LLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKG----SRLHLMPEGKHNL 274 + P I E DPL+ + +H+ ++ + P H Sbjct: 254 V-----PPCFIASAEFDPLI--DDSRLLHQTLQAHQQPCEYKMYPGTLHAF 297 >5JZX-A nrPDB Length = 405 Score = 29.4 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 4/21 (19%), Positives = 5/21 (23%) Query: 23 GIHVPRAGPAAAFGTSVTSAK 43 G H+ G K Sbjct: 18 GSHMASMTGGQQMGRGSEFMK 38 >3BGK-A nrPDB Length = 311 Score = 29.4 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >3MGC-A nrPDB Length = 319 Score = 29.4 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >3TKA-A nrPDB Length = 347 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 13/36 (36%), Gaps = 7/36 (19%) Query: 23 GIHVPRAGPAAAFGTSVTSAK-------VAVNGVQL 51 G H+ G + + K AVNG+ + Sbjct: 20 GSHMASMTGGQQMGRMMENYKHTTVLLDEAVNGLNI 55 >4L7V-A nrPDB Length = 225 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 1 GSHMASMTGGQQMGRGS 17 >2BHS-A nrPDB Length = 303 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 42/144 (29%), Gaps = 24/144 (16%) Query: 42 AKVAVNGVQLHYQQTGE-------GDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAW 94 + HY TG G + T ++ +K + + Sbjct: 140 QFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTITGVSRFMREQSKPV--TIVG 197 Query: 95 DPRGYGHSRPPDRDFPADFF-----ERDAKDAVDL--------MKALKFKKVSLLGWSDG 141 G S P R +P ++ + +D+ M+ L ++ G S G Sbjct: 198 LQPEEGSSIPGIRRWPTEYLPGIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSG 257 Query: 142 GIT--ALIAAAKYPSYIHKMVIWG 163 G AL A P + +I Sbjct: 258 GAVAGALRVAKANPDAVVVAIICD 281 >5AUQ-A nrPDB Length = 248 Score = 29.4 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 31/80 (38%), Gaps = 2/80 (2%) Query: 45 AVNGVQLHYQQTGEGDHAVL-LLPGMLGSGETDFGPQLK-NLNKKLFTVVAWDPRGYGHS 102 A++ ++ EG ++ ++ G G G++ L L +K + V D +G S Sbjct: 3 AIDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGAS 62 Query: 103 RPPDRDFPADFFERDAKDAV 122 F F + + V Sbjct: 63 DHVILGFEPKEFPEEDRGVV 82 >3UDT-A nrPDB Length = 493 Score = 29.4 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 15/51 (29%), Gaps = 3/51 (5%) Query: 23 GIHVPRAGPAAAFGTSVTSAKV-AVNGVQLHYQQTGEGDHAVLLLPGMLGS 72 G H+ G + + + Y+ GEG ++L Sbjct: 18 GSHMASMTGGQQMGRILMEMILEEKDASDWIYR--GEGGANLVLAYAGSSP 66 >3W53-A nrPDB Length = 506 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 23 GIHVPRAGPAAAFGTSV 39 G H+ G Sbjct: 18 GSHMASMTGGQQMGRGS 34 >4QNN-A nrPDB Length = 300 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 46/153 (30%), Gaps = 20/153 (13%) Query: 61 HAVLLLPGMLGS-GETDFGPQLKNLNKKL-FTVVAWDPRGYGHSRP-------------P 105 V + G S +F K L+ K + V+ D R + Sbjct: 45 QVVFITHGFTSSADTENFLAMAKALSDKGNYLVILIDWRVAACTEEMSGIQLAYYSYAAS 104 Query: 106 DRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGAN 165 + ++ K V + + L+G S G T+ A K + ++ + + Sbjct: 105 NTRLVGNYIATVTKMLVQKYN-VPMANIRLIGHSLGAHTS-GFAGK---KVQELGLGKYS 159 Query: 166 AYVTDEDSMIYEGIRDVSKWSERTRKPLEALYG 198 + + + D S+ +T + Sbjct: 160 EIIGLDPAGPSFKSNDCSERICKTDAHYVQIIH 192 >3F4L-A nrPDB Length = 345 Score = 29.0 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 47/153 (30%), Gaps = 2/153 (1%) Query: 29 AGPAAAFGTSVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKL 88 A + V V +Y+ E + G G Q+ +L + Sbjct: 132 LTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLGVHTMD-QIISLFGRP 190 Query: 89 FTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIA 148 V A+D R + PD F A F D K V +K + G Sbjct: 191 DHV-AYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHGKKGSFIKYG 249 Query: 149 AAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRD 181 + + + ++ G + D+ + E + D Sbjct: 250 IDQQETSLKANIMPGEPGFAADDSVGVLEYVND 282 >3Q9V-A nrPDB Length = 133 Score = 29.0 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 4/18 (22%), Positives = 6/18 (33%) Query: 23 GIHVPRAGPAAAFGTSVT 40 G H+ G S + Sbjct: 20 GSHMASMTGGQQMGRSES 37 >1HPL-A nrPDB Length = 449 Score = 29.0 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 17/170 (10%), Positives = 46/170 (27%), Gaps = 19/170 (11%) Query: 41 SAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGSGETDFGPQLKN--LNKKLFTVVAWDPRG 98 ++ + + G ++ G + GE + + + + D Sbjct: 50 FQEIVADPSTIQSSNFNTGRKTRFIIHGFIDKGEESWLSTMCQNMFKVESVNCICVD--- 106 Query: 99 YGHSRPPDRDFPADFFERDAKDAVDLMKALKFK------KVSLLGWSDGGITALIAAAKY 152 + + + L+ L+ V ++G S G A A + Sbjct: 107 WKSGSRTAYSQASQNVRIVGAEVAYLVGVLQSSFDYSPSNVHIIGHSLGSHAAGEAGRRT 166 Query: 153 PSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYF 202 + + I G + ++G ++ + + + D Sbjct: 167 NGAVGR--ITGLDPAEP-----CFQGTPELVRLD-PSDAQFVDVIHTDIA 208 >6OAZ-A nrPDB Length = 448 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 31/97 (31%), Gaps = 17/97 (17%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLNKKLF------TVVAWDPRGYGHSRPPDRDFPADFF 114 +++ G +G + + L L+ V+ D + A + Sbjct: 47 KTFMVIHGWTVTGM--YESWVPKLVAALYKREPDSNVIVVD---WLSRAQEHYPVSAGYT 101 Query: 115 ERDAKDAVDLMKALK------FKKVSLLGWSDGGITA 145 + +D + ++ V LLG+S G A Sbjct: 102 KLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAA 138 >5LOB-A nrPDB Length = 162 Score = 28.6 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 3/24 (12%), Positives = 5/24 (20%) Query: 25 HVPRAGPAAAFGTSVTSAKVAVNG 48 H+ G + G Sbjct: 1 HMASMTGGQQMGRGSDFGDIEERG 24 >4XWN-A nrPDB Length = 681 Score = 28.6 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 6/37 (16%), Positives = 9/37 (24%), Gaps = 4/37 (10%) Query: 23 GIHVPRAGPAAAFGTSVTSAK----VAVNGVQLHYQQ 55 G H+ G V N H++ Sbjct: 18 GSHMASMTGGQQMGRIEGREFAAPVVPNNEYVQHFKD 54 >3Q6B-A nrPDB Length = 189 Score = 28.6 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 9/26 (34%), Gaps = 1/26 (3%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVNG 48 G H+ G S V V+G Sbjct: 20 GSHMASMTGGQQMGRYKLSG-VEVSG 44 >5AH0-A nrPDB Length = 387 Score = 28.6 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 24/78 (30%), Gaps = 3/78 (3%) Query: 71 GSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFERDAKDAVDLMKALKF 130 G +++ + V + G+ HS + + +L K Sbjct: 49 GPVSSNWDRACELYAYIKGGTVDY---GHAHSTQKGHSRYGRTYPGLYPEWGNLTTEGKV 105 Query: 131 KKVSLLGWSDGGITALIA 148 K+ L+ S GG T Sbjct: 106 NKIHLVAHSMGGQTVRTL 123 >2QT9-A nrPDB Length = 766 Score = 28.2 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 64/210 (30%), Gaps = 42/210 (20%) Query: 76 DFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDR--------DFPADFFERDAKDAVDLMKA 127 ++ L + + V ++D RG G+ F + A+ M Sbjct: 562 NWATYLA--STENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSK-MGF 618 Query: 128 LKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSE 187 + K++++ GWS GG Y+ MV+ + + VS+W Sbjct: 619 VDNKRIAIWGWSYGG------------YVTSMVLGSGSGVFK-----CGIAVAPVSRWEY 661 Query: 188 RTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLV 247 E G T E +D R + + Q L++HG D V Sbjct: 662 YDSVYTERYMGL----PTPEDNLDHYRNSTVMSRAENFK------QVEYLLIHGTADDNV 711 Query: 248 PRFHADFIHKHVKGS----RLHLMPEGKHN 273 + I K + + + H Sbjct: 712 HFQQSAQISKALVDVGVDFQAMWYTDEDHG 741 >4AMY-A nrPDB Length = 710 Score = 28.2 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 46/271 (16%), Positives = 88/271 (32%), Gaps = 53/271 (19%) Query: 44 VAVNGVQLHYQQTGEGDHAVLLLP--GMLGSGETDFGPQLKNLNKKLFTVVAW-DPRGYG 100 V G++L +G H L G S ++ + + V+A + RG G Sbjct: 455 VHKKGIKL------DGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGG 508 Query: 101 HSRPPDRDFPADFFERDAKDAVDLMK-ALKF---------KKVSLLGWSDGGITALIAAA 150 + + ++ D + A ++ K++++ G S+GG+ A Sbjct: 509 ---EYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCAN 565 Query: 151 KYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWV 210 + P ++ A V D + + W+ DY ++ Sbjct: 566 QRPDLFGCVI-----AQVGVMDMLKFHKYTIGHAWTT------------DYGCSDSKQ-- 606 Query: 211 DGIRQFKHLPDGNICRHLLPRVQCPA--LIVHGEKDPLVPRFHADFIHKH---VKGSRL- 264 K+ P N+ +Q P+ L+ D +VP FI V SR Sbjct: 607 HFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQ 666 Query: 265 ------HLMPEGKHNLHLRFADEFNKLAEDF 289 H+ + H A ++++ F Sbjct: 667 NNPLLIHVDTKAGHGAGKPTAKVIEEVSDMF 697 >1V02-A nrPDB Length = 565 Score = 28.2 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 29/97 (29%), Gaps = 1/97 (1%) Query: 137 GWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEAL 196 G + G T YP +H +++ N Y + G+ D+ K LE Sbjct: 416 GNAIGPPTGNAWINMYPKGLHDILMTMKNKYGNPPMYITENGMGDIDKGDLPKPVALEDH 475 Query: 197 YGYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQ 233 DY R I G LL + Sbjct: 476 TRLDYIQRHLSVLKQSID-LGADVRGYFAWSLLDNFE 511 >4MSX-A nrPDB Length = 482 Score = 28.2 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 3/15 (20%), Positives = 4/15 (26%) Query: 23 GIHVPRAGPAAAFGT 37 G H+ G Sbjct: 18 GSHMASMTGGQQMGR 32 >4Q3K-A nrPDB Length = 260 Score = 27.8 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 45/120 (37%), Gaps = 8/120 (6%) Query: 61 HAVLLLPGMLGSGETDFGPQLKNLN--KKLFT--VVAWDPRGYGHSRPPDRDFPADFFER 116 A+L+ PG +D + L+ K + V+ + + + P D D Sbjct: 55 PAMLIFPGGGYQFCSDREAEPIALSYLAKGYNAFVLRYSVKEHAVFPRPLIDAE-DALSY 113 Query: 117 DAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIY 176 +A L + K++++G+S GG A A + V+ G A + E + Sbjct: 114 LKDNAHAL--HINPDKIAVIGFSAGGHLATTLATEGKVR-PNAVVLGYPALIRHEKYWNF 170 >6AQO-A nrPDB Length = 272 Score = 27.8 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 3/17 (17%), Positives = 4/17 (23%) Query: 25 HVPRAGPAAAFGTSVTS 41 H+ G S Sbjct: 25 HMASMTGGQQMGRGSHS 41 >3LS2-A nrPDB Length = 280 Score = 27.8 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 38/121 (31%), Gaps = 24/121 (19%) Query: 58 EGDHAVLLLPGMLGSGETDFGPQLKNLNKK---LFTVVAWD--PRGYG--HSRPPDRDFP 110 VL L + +F + K +VA D PRG + D Sbjct: 42 SNKVPVLYWLSGLTCTDENFMQKAGAFKKAAELGIAIVAPDTSPRGDNVPNEDSYDFAQG 101 Query: 111 ADFFERDAKD-----------AVDLMKALKFKKVSLL------GWSDGGITALIAAAKYP 153 A F+ + V+ + AL + + G S GG AL+ A K P Sbjct: 102 AGFYVNATQAPYNTHFNMYDYVVNELPALIEQHFPVTSTKAISGHSMGGHGALMIALKNP 161 Query: 154 S 154 Sbjct: 162 Q 162 >4LIV-A nrPDB Length = 407 Score = 27.8 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 4/25 (16%), Positives = 8/25 (32%) Query: 23 GIHVPRAGPAAAFGTSVTSAKVAVN 47 G H+ G ++ +N Sbjct: 18 GSHMASMTGGEEMGRGSMEYQLTLN 42 >2X4L-A nrPDB Length = 325 Score = 27.8 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 33/97 (34%), Gaps = 12/97 (12%) Query: 128 LKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSE 187 L KV++LG G + A+ P ++I S+ E V+K Sbjct: 86 LDVDKVTVLGNEWGKLNVEKYASLAPE----VLITTTFDTAGTLWSVPEESKDKVAKL-- 139 Query: 188 RTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPDGNI 224 P A+ +D R + + + + ++ Sbjct: 140 ---APSVAISVFD---RQLTQPLQRMWELAESLGADM 170 >5LW6-A nrPDB Length = 255 Score = 27.8 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 5/19 (26%) Query: 23 GIHVPRAGPAAAFGTSVTS 41 G H+ G + Sbjct: 18 GSHMASMTGGNNMGAGSSK 36 >5GW8-A nrPDB Length = 286 Score = 27.8 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 27/77 (35%), Gaps = 10/77 (12%) Query: 83 NLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFER-DAKDAVDLMKALKF-------KKVS 134 +L+ V D R P + F++ D+ +K +V+ Sbjct: 91 DLHDAQLRPVDPDSRY--RRFLPQGTKVMNGFQKGYTDLVDDIFDHVKKFKQEKNESRVT 148 Query: 135 LLGWSDGGITALIAAAK 151 ++G S G L+A+ Sbjct: 149 VIGHSLGAAIGLLASLD 165 >3MGA-A nrPDB Length = 407 Score = 27.4 bits (59), Expect = 6.5, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 21/50 (42%), Gaps = 1/50 (2%) Query: 129 KFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEG 178 + + G S GG++AL A +P+ V+ + ++ EG Sbjct: 279 DAGRTVVAGQSFGGLSALYAGLNWPTRF-GCVLSQSGSFWWPHRITPPEG 327 >4BZW-A nrPDB Length = 282 Score = 27.4 bits (59), Expect = 6.6, Method: Composition-based stats. Identities = 25/176 (14%), Positives = 44/176 (25%), Gaps = 35/176 (19%) Query: 108 DFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAY 167 D+ A + +++ L G+S GG V Sbjct: 90 GATIDWITTQASA-----HHVDCQRIILAGFSAGGHVVATYNG---------VATQPELR 135 Query: 168 VTDEDSMIYEGIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDGIRQFKHLPD---GNI 224 + + GY T + + D Sbjct: 136 TRYH-------------LDHYQGQHAAIILGYPVIDLTAGFPTTSAARNQITTDARLWAA 182 Query: 225 CRHLLPRVQCPALIVHGEKDPLVPRFHADFIHKHVKGSRL----HLMPEGKHNLHL 276 R + P + PA + D VP ++ + + ++ HL G H L L Sbjct: 183 QRLVTPASK-PAFVWQTATDESVPPINSLKYVQAMLQHQVATAYHLFGSGIHGLAL 237 >1R88-A nrPDB Length = 280 Score = 27.4 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 44/121 (36%), Gaps = 7/121 (5%) Query: 59 GDHAVLLL-PGMLGSGETDF---GPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFF 114 G HAV LL G +++ G + L K +VVA Y ++D + Sbjct: 33 GPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKGISVVAPAGGAYSMYTNWEQDGSKQWD 92 Query: 115 ERDAKDAVDLMKA---LKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTDE 171 + + D + A L + +G + GG A+ AA +P Y ++ Sbjct: 93 TFLSAELPDWLAANRGLAPGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNT 152 Query: 172 D 172 Sbjct: 153 T 153 >2HFJ-A nrPDB Length = 319 Score = 27.4 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 38/221 (17%), Positives = 65/221 (29%), Gaps = 16/221 (7%) Query: 55 QTGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDF-PADF 113 EG ++ G +G +L ++ +A GYG PAD Sbjct: 84 DRAEGRAVLVGCTGTAANGGPHEFLRLSTSFQEERDFLAVPLPGYGTGTGTGTALLPADL 143 Query: 114 FERDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAK----YPSYIHKMVIWGANAYVT 169 A +++A V LLG S G + A A + + + +V+ Sbjct: 144 DTALDAQARAILRAAGDAPVVLLGHSGGALLAHELAFRLERAHGAPPAGIVLVDPYPPGH 203 Query: 170 DEDSMIYEGIRDVSKWSER----TRKPLEALYGYDYFART-----CEKWVDGIRQFKHLP 220 E ++ ++ + L A+ Y F V +R + L Sbjct: 204 QEPIEVWSRQLGEGLFAGELEPMSDARLLAMGRYARFLAGPRPGRSSAPVLLVRASEPLG 263 Query: 221 DGNICR-HLLPRVQCPALIVHGEKDPLVPR-FHADFIHKHV 259 D R P + D HA + + V Sbjct: 264 DWQEERGDWRAHWDLPHTVADVPGDHFTMMRDHAPAVAEAV 304 >6AGQ-A nrPDB Length = 321 Score = 27.1 bits (58), Expect = 8.4, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 24/73 (32%), Gaps = 5/73 (6%) Query: 47 NGVQLH---YQQTGEGDH--AVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGH 101 +G +H GE +L+ SG + +L +A D RG G Sbjct: 66 DGTPIHGWYVTPKGEHQPGSLPVLVKYHGYSGNRGYPNELLQWASMGMAALAIDVRGQGG 125 Query: 102 SRPPDRDFPADFF 114 P ++P Sbjct: 126 VTPDRAEYPQGGI 138 >6CL4-A nrPDB Length = 313 Score = 27.1 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 35/109 (32%), Gaps = 15/109 (13%) Query: 62 AVLLLPGMLGSG-----ETDFGPQLKNLNKKLFTV-VAWDPRGYGHSRPPDRDFPADFFE 115 ++L+ G+LG F + L K V +A S + + Sbjct: 29 PIVLVHGLLGFDKIGGIYPYFYGIKEALEKAGAKVYIAT------LSALNSNELRGEQLL 82 Query: 116 RDAKDAVDLMKALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVIWGA 164 + A KV+L+G S G + AA +P I + Sbjct: 83 EFVRKVQAETGA---AKVNLIGHSQGPLACRYVAATHPELIASVTSVNG 128 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.125 0.301 Lambda K H 0.267 0.0383 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,233,991 Number of Sequences: 36641 Number of extensions: 391252 Number of successful extensions: 1817 Number of sequences better than 10.0: 338 Number of HSP's better than 10.0 without gapping: 263 Number of HSP's successfully gapped in prelim test: 121 Number of HSP's that attempted gapping in prelim test: 1316 Number of HSP's gapped (non-prelim): 443 length of query: 291 length of database: 10,336,785 effective HSP length: 96 effective length of query: 195 effective length of database: 6,819,249 effective search space: 1329753555 effective search space used: 1329753555 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (27.0 bits)