BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q86SR1 (603 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2D7R-A nrPDB 1184 0.0 6IWR-A nrPDB 400 e-112 5NQA-A nrPDB 393 e-109 5AJO-A nrPDB 343 1e-94 2Z87-A nrPDB 41 0.001 6HNQ-B nrPDB 40 0.003 1IT0-A nrPDB 40 0.004 5MLZ-A nrPDB 38 0.010 1RZO-B nrPDB 31 1.2 5VAQ-A nrPDB 31 1.6 3WN1-A nrPDB 31 1.7 3A22-A nrPDB 31 1.8 1HWM-B nrPDB 30 2.1 3RTJ-B nrPDB 30 2.6 1AOC-A nrPDB 30 3.5 6HD5-v nrPDB 30 3.7 >2D7R-A nrPDB Length = 570 Score = 1184 bits (3062), Expect = 0.0, Method: Compositional matrix adjust. Identities = 564/564 (100%), Positives = 564/564 (100%) Query: 40 PGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT 99 PGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT Sbjct: 7 PGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT 66 Query: 100 DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWS 159 DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWS Sbjct: 67 DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWS 126 Query: 160 SLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIR 219 SLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIR Sbjct: 127 SLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIR 186 Query: 220 TRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQ 279 TRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQ Sbjct: 187 TRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQ 246 Query: 280 AGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGL 339 AGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGL Sbjct: 247 AGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGL 306 Query: 340 EIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMD 399 EIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMD Sbjct: 307 EIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMD 366 Query: 400 EYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAA 459 EYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAA Sbjct: 367 EYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAA 426 Query: 460 WGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT 519 WGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT Sbjct: 427 WGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT 486 Query: 520 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCN 579 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCN Sbjct: 487 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCN 546 Query: 580 PSSLTQQWLFEHTNSTVLEKFNRN 603 PSSLTQQWLFEHTNSTVLEKFNRN Sbjct: 547 PSSLTQQWLFEHTNSTVLEKFNRN 570 >6IWR-A nrPDB Length = 597 Score = 400 bits (1029), Expect = e-112, Method: Compositional matrix adjust. Identities = 216/524 (41%), Positives = 314/524 (59%), Gaps = 30/524 (5%) Query: 88 GNGEQGRPYPMTD--AERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLP 145 G GE+ +P + + + + +E GFN+ SD ISL+RS+ D+R C Y E L Sbjct: 88 GPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLL 147 Query: 146 NTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPS 205 +S++I FHNEGWS+L+RTVHSV+ R+P + +AEIVL+DDFS++EHLK+ L++Y+ L+ Sbjct: 148 TSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNG 207 Query: 206 -VRILRTKKREGLIRTRMLGASVAT-GDVITFLDSHCEANVNWLPPLLDRIARNRKTIVC 263 V++ R ++REGLI+ R +GA A G V+ +LD+HCE VNW PL+ I+++R Sbjct: 208 LVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTV 267 Query: 264 PMIDVIDHDDFRYETQAG----DAMRGAFDWEMYYKRIPIPPELQ--KADPSDPFESPVM 317 P+IDVI+ + + Q G RGA+DW M +KR+P+ P+ + + ++P+ SP M Sbjct: 268 PLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKTEPYRSPAM 327 Query: 318 AGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYR---- 373 AGGLFA++R++F+ELG YDPGL+IWGGE +EIS+K+W CGG++ +PCSRVGHIYR Sbjct: 328 AGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGW 387 Query: 374 KYVPYKVPAGVS-LARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNC 432 + P + G S +N RV EVW DEY +Y Y RPE + L GD++ KK R NC Sbjct: 388 QGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYGDISELKKFREDHNC 447 Query: 433 KSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGR 492 KSFKWFM +IA+D+ Y P+ P WGEIR T C D+ G + L C R Sbjct: 448 KSFKWFMEEIAYDITSHY-PLPPKNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMG 506 Query: 493 GEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKD 552 G Q+F + D C + S V + C ++ + W+Y K+ Sbjct: 507 GN------QLFRINEANQLMQYDQ------CLTKGADGSKVMITHC-NLNEFKEWQYFKN 553 Query: 553 -KTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNST 595 H SG C+D SE H++F++ C+ S TQ+W + +S Sbjct: 554 LHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 597 >5NQA-A nrPDB Length = 578 Score = 393 bits (1010), Expect = e-109, Method: Compositional matrix adjust. Identities = 212/494 (42%), Positives = 293/494 (59%), Gaps = 32/494 (6%) Query: 112 GFNIYVSDKISLNRSLPDIRHPNCNSKRY-LETLPNTSIIIPFHNEGWSSLLRTVHSVLN 170 NIY+SD+ISL+R + D R C S+++ TLP TS+II F+NE WS+LLRT+HSVL Sbjct: 101 AINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLE 160 Query: 171 RSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTRMLGASVATG 230 SP L+ EI+LVDD SDR +LK LE Y++ VR++RT KREGL+R R++GA+ ATG Sbjct: 161 TSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVRLIRTNKREGLVRARLIGATFATG 220 Query: 231 DVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDW 290 DV+TFLD HCE N WL PLL+RI R+ +VCP+ID ID + F + Q G+ M G FDW Sbjct: 221 DVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDW 280 Query: 291 EMYYKRIPIPPELQKADPS--DPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYE 348 + ++ +P + + S DP SP MAGGLFAV +K+F LG YD G+E+WGGE E Sbjct: 281 RLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLE 340 Query: 349 ISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEYIYQR 408 +SF+VW CGG++E PCS VGH++ K PY P + +N R AEVWMDEY E+ Y R Sbjct: 341 LSFRVWQCGGKLEIHPCSHVGHVFPKRAPYARP---NFLQNTARAAEVWMDEYKEHFYNR 397 Query: 409 RPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAW-GEIRNVG 467 P R + GD++ +K LR L CKSF W++ + P + P + P W G IR+ G Sbjct: 398 NPPARKEAYGDISERKLLRERLRCKSFDWYLKNV---FPNLHVPEDRP--GWHGAIRSRG 452 Query: 468 -TGLCADTK---HGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFC 523 + C D + G+ L L GC G+G Q F +T ++IR + C Sbjct: 453 ISSECLDYNSPDNNPTGANLSLFGC-HGQG-----GNQFFEYTSNKEIRFNS---VTELC 503 Query: 524 FDAISHTSPVTLYDC----HSMKGNQLWKYRKDKTLYHPVSGSCMDC---SESDHRIFMN 576 + + V + +C + N +W +++D T++HP SG C+ E + M Sbjct: 504 AEVPEQKNYVGMQNCPKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRTPEGRPDVQMR 563 Query: 577 TCNPSSLTQQWLFE 590 TC+ Q W FE Sbjct: 564 TCDALDKNQIWSFE 577 >5AJO-A nrPDB Length = 571 Score = 343 bits (880), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 193/496 (38%), Positives = 280/496 (56%), Gaps = 43/496 (8%) Query: 108 YRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHS 167 Y N FN SDK+ ++R++PD RH C K++ LP TS++I FHNE S+LLRTV S Sbjct: 99 YARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVS 158 Query: 168 VLNRSPPELVAEIVLVDDFSDREHLKKPLED--YMALFPSVRILRTKKREGLIRTRMLGA 225 VL +SPP L+ EI+LVDD+S+ ED + VR+LR +REGL+R+R+ GA Sbjct: 159 VLKKSPPHLIKEIILVDDYSNDP------EDGALLGKIEKVRVLRNDRREGLMRSRVRGA 212 Query: 226 SVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMR 285 A V+TFLDSHCE N +WL PLL+R+A +R +V P+IDVI+ D+F+Y + D ++ Sbjct: 213 DAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASAD-LK 271 Query: 286 GAFDWEMYYKRIPIPPELQKA---DPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIW 342 G FDW + +K + PE +++ +P P ++P++AGGLF +D+ +F ELG YD +++W Sbjct: 272 GGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVW 331 Query: 343 GGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVP--AGVSLARNLKRVAEVWMDE 400 GGE EISF+VW CGG +E IPCSRVGH++RK PY P +G ARN +R AEVWMDE Sbjct: 332 GGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDE 391 Query: 401 YAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPP---A 457 Y + Y P R++ G++ + +LR L+CK FKW++ + YP + P Sbjct: 392 YKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENV-------YPELRVPDHQD 444 Query: 458 AAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQ 517 A+G ++ GT C DT + + C G W T + ++ D Sbjct: 445 IAFGALQQ-GTN-CLDTLGHFADGVVGVYECHNAGGNQEW------ALTKEKSVKHMD-- 494 Query: 518 HTKKFCFDAISHT--SPVTLYDCHSMKGNQLW-KYRKDKTLYHPVSGSCMDC-SESDHRI 573 C + S + L C Q W + + L H S C+D + + Sbjct: 495 ----LCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGL 550 Query: 574 FMNTCNPSSLTQQWLF 589 + C P +L+QQW F Sbjct: 551 SVEVCGP-ALSQQWKF 565 >2Z87-A nrPDB Length = 624 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 51/244 (20%), Positives = 99/244 (40%), Gaps = 31/244 (12%) Query: 148 SIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVR 207 SI+IP +N + +L + L E+++ DD S +E++++ + ++ +L +++ Sbjct: 95 SIVIPTYNR--AKILAITLACLCNQKTIYDYEVIVADDGS-KENIEEIVREFESLL-NIK 150 Query: 208 ILRTKKR-EGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKT-IVCP- 264 +R K L R LG A + + LD N W+ ++ +A + ++ P Sbjct: 151 YVRQKDYGYQLCAVRNLGLRAAKYNYVAILDCDMAPNPLWVQSYMELLAVDDNVALIGPR 210 Query: 265 -MIDVIDHDDFRYETQ----------------AGDAMRG-AFDWEMYYKRIPIPPELQKA 306 ID H + +Q AG + + DW + + + L Sbjct: 211 KYIDTSKHTYLDFLSQKSLINEIPEIITNNQVAGKVEQNKSVDWRIEHFKNTDNLRL--- 267 Query: 307 DPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCS 366 + PF +GG A +KW + G +D WGGE E ++++ G + + Sbjct: 268 -CNTPFR--FFSGGNVAFAKKWLFRAGWFDEEFTHWGGEDNEFGYRLYREGCYFRSVEGA 324 Query: 367 RVGH 370 H Sbjct: 325 MAYH 328 >6HNQ-B nrPDB Length = 345 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Query: 143 TLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFS-DREHLKKPLEDYMA 201 ++ S+I+P N G L RT+ SVLN++ E++++DD S D ++ Y Sbjct: 18 SMKKVSVIMPTFNNG-EKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETLNVIKKYKG 76 Query: 202 LFPSVRILRTKKREGLIRT-RMLGASVATGDVITFLDS 238 L VR + KK G R G ++ + + FLDS Sbjct: 77 L---VRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDS 111 >1IT0-A nrPDB Length = 436 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 19/116 (16%) Query: 455 PPAAAWGEIRNVGTGLCADTKHGAL--GSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIR 512 PP + G+I+ VG+G C D + + G+ ++L C +A N Q +T+T ++R Sbjct: 307 PPPSGGGQIKGVGSGRCLDVPNASTTDGTQVQLYDC-----HSATN--QQWTYTDAGELR 359 Query: 513 P-GDPQHTKKFCFDA--ISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMD 565 GD C DA + + V +Y C NQ W+ D ++ SG C+D Sbjct: 360 VYGDK------CLDAAGTGNGTKVQIYSCWGGD-NQKWRLNSDGSIVGVQSGLCLD 408 >5MLZ-A nrPDB Length = 374 Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 5/115 (4%) Query: 140 YLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDY 199 Y +++ S+IIP +NE L + S ++ + L EIV+VDD S +K ++ Sbjct: 19 YFQSM-KVSVIIPTYNE--RENLEELFSRIDNALQGLNYEIVVVDDDSPDRTWEKA-QEL 74 Query: 200 MALFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRI 254 + +P V+++R K +GL + G A+GDV +D+ + +P L++ I Sbjct: 75 SSKYP-VKVIRRTKEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPKLIEAI 128 >1RZO-B nrPDB Length = 262 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query: 522 FCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLY-HPVSGSCM--DCSESDHRIFMNTC 578 C A ++ V L DC S K Q W D ++ +C+ D + + + +C Sbjct: 150 MCLQA--NSGKVWLEDCTSEKAEQQWALYADGSIRPQQNRDNCLTTDANIKGTVVKILSC 207 Query: 579 NPSSLTQQWLFEHTNSTVLEKFN 601 P+S Q+W+F++ + T+L +N Sbjct: 208 GPASSGQRWMFKN-DGTILNLYN 229 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 5/56 (8%) Query: 531 SPVTLYDCHSMKG-NQLWKYRKDKTLYHPVSGSCMDCSESDHR--IFMNTCNPSSL 583 +P+ L+ C S NQLW RKD T+ +G C+ S+S R + + C+ +++ Sbjct: 32 NPIQLWPCKSNTDWNQLWTLRKDSTIRS--NGKCLTISKSSPRQQVVIYNCSTATV 85 >5VAQ-A nrPDB Length = 954 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 9/60 (15%) Query: 73 DWHDKEAIRRDAQRVG-NGEQGRPYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIR 131 +W D IRR V N +Q P + A Q RENGF SL S PD++ Sbjct: 438 EWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGF--------SLKESTPDVQ 489 >3WN1-A nrPDB Length = 438 Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust. Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 24/140 (17%) Query: 458 AAWGEIRNVGTGLCADTKHGAL--GSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGD 515 A G +R G+ C D G+ G+ L+L C G + W + T D Sbjct: 1 AGSGALRGAGSNRCLDVLGGSQDDGALLQLYDCWGGTNQQ-WTSTDTGRLTVYGDK---- 55 Query: 516 PQHTKKFCFDAISH-TSP---VTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC----S 567 C D H T+P V ++ C S NQ W+ D T+ SG C++ + Sbjct: 56 -------CLDVPGHATAPGTRVQIWSC-SGGANQQWRVNSDGTVVGVESGLCLEAAGAGT 107 Query: 568 ESDHRIFMNTCNPSSLTQQW 587 + + + TCN Q+W Sbjct: 108 ANGTAVQLWTCNGGG-NQKW 126 >3A22-A nrPDB Length = 614 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 523 CFDA----ISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC 566 C DA ++ + V ++DC+ + NQ W D T+ + +G C+D Sbjct: 541 CLDAYNLGTTNGTKVVIWDCNG-QANQKWNINSDGTITNVNAGLCLDA 587 >1HWM-B nrPDB Length = 266 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 35/147 (23%), Positives = 53/147 (36%), Gaps = 15/147 (10%) Query: 461 GEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT- 519 G I N +GL GA + L LE + + +T D++P Sbjct: 96 GSIINPSSGLVMTAPSGASRTTLLLENNIHAASQG---------WTVSNDVQPIATLIVG 146 Query: 520 -KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTL-YHPVSGSCMDCSE--SDHRIFM 575 + C A + V + DC Q W D+T+ + G C+ + S I + Sbjct: 147 YNEMCLQANGENNNVWMEDCDVTSVQQQWALFDDRTIRVNNSRGLCVTSNGYVSKDLIVI 206 Query: 576 NTCNPSSLTQQWLFEHTNSTVLEKFNR 602 C + TQ+W F S V K R Sbjct: 207 RKCQGLA-TQRWFFNSDGSVVNLKSTR 232 >3RTJ-B nrPDB Length = 262 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 6/83 (7%) Query: 522 FCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHR---IFMNTC 578 C A ++ V + DC S K Q W D ++ + S+S+ R + + +C Sbjct: 150 LCLQA--NSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSC 207 Query: 579 NPSSLTQQWLFEHTNSTVLEKFN 601 P+S Q+W+F++ + T+L ++ Sbjct: 208 GPASSGQRWMFKN-DGTILNLYS 229 >1AOC-A nrPDB Length = 175 Score = 29.6 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 486 EGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISH---TSPVTLYDCHSMK 542 E V GRG + +++ VF + + R P+H++ + F +H PV+ DC + Sbjct: 40 ESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVF 99 Query: 543 G 543 G Sbjct: 100 G 100 >6HD5-v nrPDB Length = 176 Score = 29.6 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 11/63 (17%) Query: 539 HSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNSTVLE 598 H G++L K+ +DK C +C + H +F+ LT+QW H V E Sbjct: 104 HKSIGSKLLKFAEDK---------CSECHQ--HNVFVYLPAVDDLTKQWFIAHGFEQVGE 152 Query: 599 KFN 601 N Sbjct: 153 TVN 155 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2D7R-A nrPDB 959 0.0 6IWR-A nrPDB 731 0.0 5NQA-A nrPDB 689 0.0 5AJO-A nrPDB 641 0.0 2Z87-A nrPDB 268 5e-72 Sequences not found previously or not previously below threshold: 1IT0-A nrPDB 66 3e-11 3WN1-A nrPDB 64 1e-10 5MLZ-A nrPDB 63 3e-10 3A22-A nrPDB 60 3e-09 5EKE-A nrPDB 53 3e-07 6HNQ-B nrPDB 53 3e-07 2Z49-A nrPDB 51 1e-06 1RZO-B nrPDB 49 8e-06 3RTJ-B nrPDB 48 1e-05 2Q3N-B nrPDB 45 1e-04 5TZ8-A nrPDB 43 4e-04 3CAH-A nrPDB 42 8e-04 5Y97-C nrPDB 42 0.001 3L7K-A nrPDB 42 0.001 1HWM-B nrPDB 41 0.001 1ABR-B nrPDB 39 0.005 2MLL-B nrPDB 37 0.029 4ZFY-B nrPDB 36 0.040 4P02-A nrPDB 35 0.062 1GGP-B nrPDB 35 0.12 3D7W-B nrPDB 35 0.13 2VLC-A nrPDB 34 0.14 2FTC-A nrPDB 33 0.30 1YF8-B nrPDB 33 0.31 4V8M-AF nrPDB 32 0.52 4DND-A nrPDB 32 0.97 5Z70-A nrPDB 31 1.5 3NBC-A nrPDB 30 2.7 1XX5-A nrPDB 29 5.8 2WAU-A nrPDB 29 6.5 4D8J-B nrPDB 29 7.2 2DM9-A nrPDB 29 7.7 2HK2-A nrPDB 29 8.3 >2D7R-A nrPDB Length = 570 Score = 959 bits (2480), Expect = 0.0, Method: Composition-based stats. Identities = 564/564 (100%), Positives = 564/564 (100%) Query: 40 PGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT 99 PGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT Sbjct: 7 PGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT 66 Query: 100 DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWS 159 DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWS Sbjct: 67 DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWS 126 Query: 160 SLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIR 219 SLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIR Sbjct: 127 SLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIR 186 Query: 220 TRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQ 279 TRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQ Sbjct: 187 TRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQ 246 Query: 280 AGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGL 339 AGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGL Sbjct: 247 AGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGL 306 Query: 340 EIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMD 399 EIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMD Sbjct: 307 EIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMD 366 Query: 400 EYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAA 459 EYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAA Sbjct: 367 EYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAA 426 Query: 460 WGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT 519 WGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT Sbjct: 427 WGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT 486 Query: 520 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCN 579 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCN Sbjct: 487 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCN 546 Query: 580 PSSLTQQWLFEHTNSTVLEKFNRN 603 PSSLTQQWLFEHTNSTVLEKFNRN Sbjct: 547 PSSLTQQWLFEHTNSTVLEKFNRN 570 >6IWR-A nrPDB Length = 597 Score = 731 bits (1887), Expect = 0.0, Method: Composition-based stats. Identities = 216/524 (41%), Positives = 314/524 (59%), Gaps = 30/524 (5%) Query: 88 GNGEQGRPYPMTD--AERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLP 145 G GE+ +P + + + + +E GFN+ SD ISL+RS+ D+R C Y E L Sbjct: 88 GPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLL 147 Query: 146 NTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPS 205 +S++I FHNEGWS+L+RTVHSV+ R+P + +AEIVL+DDFS++EHLK+ L++Y+ L+ Sbjct: 148 TSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNG 207 Query: 206 -VRILRTKKREGLIRTRMLGASVAT-GDVITFLDSHCEANVNWLPPLLDRIARNRKTIVC 263 V++ R ++REGLI+ R +GA A G V+ +LD+HCE VNW PL+ I+++R Sbjct: 208 LVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTV 267 Query: 264 PMIDVIDHDDFRYETQAG----DAMRGAFDWEMYYKRIPIPPELQ--KADPSDPFESPVM 317 P+IDVI+ + + Q G RGA+DW M +KR+P+ P+ + + ++P+ SP M Sbjct: 268 PLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKTEPYRSPAM 327 Query: 318 AGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYR---- 373 AGGLFA++R++F+ELG YDPGL+IWGGE +EIS+K+W CGG++ +PCSRVGHIYR Sbjct: 328 AGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGW 387 Query: 374 KYVPYKVPAGVS-LARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNC 432 + P + G S +N RV EVW DEY +Y Y RPE + L GD++ KK R NC Sbjct: 388 QGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYGDISELKKFREDHNC 447 Query: 433 KSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGR 492 KSFKWFM +IA+D+ Y P+ P WGEIR T C D+ G + L C R Sbjct: 448 KSFKWFMEEIAYDITSHY-PLPPKNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMG 506 Query: 493 GEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKD 552 G Q+F + D C + S V + C ++ + W+Y K+ Sbjct: 507 GN------QLFRINEANQLMQYDQ------CLTKGADGSKVMITHC-NLNEFKEWQYFKN 553 Query: 553 -KTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNST 595 H SG C+D SE H++F++ C+ S TQ+W + +S Sbjct: 554 LHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 597 >5NQA-A nrPDB Length = 578 Score = 689 bits (1777), Expect = 0.0, Method: Composition-based stats. Identities = 223/561 (39%), Positives = 317/561 (56%), Gaps = 38/561 (6%) Query: 50 AAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRR---DAQRVGNGEQGRPYPMTDAERVDQ 106 +AG G +R+ + L D QK + + ++ D++ +G + + + E Q Sbjct: 35 SAGAG-RARELGSRRLSDLQKNTEDLSRPLYKKPPADSRALGEWGKASKLQLNEDELKQQ 93 Query: 107 A--YRENGFNIYVSDKISLNRSLPDIRHPNCNSKRY-LETLPNTSIIIPFHNEGWSSLLR 163 NIY+SD+ISL+R + D R C S+++ TLP TS+II F+NE WS+LLR Sbjct: 94 EELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLR 153 Query: 164 TVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTRML 223 T+HSVL SP L+ EI+LVDD SDR +LK LE Y++ VR++RT KREGL+R R++ Sbjct: 154 TIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVRLIRTNKREGLVRARLI 213 Query: 224 GASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDA 283 GA+ ATGDV+TFLD HCE N WL PLL+RI R+ +VCP+ID ID + F + Q G+ Sbjct: 214 GATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEP 273 Query: 284 MRGAFDWEMYYKRIPIPPELQKADPS--DPFESPVMAGGLFAVDRKWFWELGGYDPGLEI 341 M G FDW + ++ +P + + S DP SP MAGGLFAV +K+F LG YD G+E+ Sbjct: 274 MIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEV 333 Query: 342 WGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEY 401 WGGE E+SF+VW CGG++E PCS VGH++ K PY P + +N R AEVWMDEY Sbjct: 334 WGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPYARP---NFLQNTARAAEVWMDEY 390 Query: 402 AEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAW- 460 E+ Y R P R + GD++ +K LR L CKSF W++ + P + P + P W Sbjct: 391 KEHFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNV---FPNLHVPEDRP--GWH 445 Query: 461 GEIRNVG-TGLCADTK---HGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDP 516 G IR+ G + C D + G+ L L GC G Q F +T ++IR Sbjct: 446 GAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQGGN------QFFEYTSNKEIRFNS- 498 Query: 517 QHTKKFCFDAISHTSPVTLYDC----HSMKGNQLWKYRKDKTLYHPVSGSCMDC---SES 569 + C + + V + +C + N +W +++D T++HP SG C+ E Sbjct: 499 --VTELCAEVPEQKNYVGMQNCPKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRTPEG 556 Query: 570 DHRIFMNTCNPSSLTQQWLFE 590 + M TC+ Q W FE Sbjct: 557 RPDVQMRTCDALDKNQIWSFE 577 >5AJO-A nrPDB Length = 571 Score = 641 bits (1654), Expect = 0.0, Method: Composition-based stats. Identities = 198/550 (36%), Positives = 294/550 (53%), Gaps = 59/550 (10%) Query: 72 KDWHDKEAIRRDAQRVGNGE-QGRPYPMTDAERV-------------------DQAYREN 111 +DW++ + I++ NGE + + +V Y N Sbjct: 43 EDWNEIDPIKKKDLHHSNGEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARN 102 Query: 112 GFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNR 171 FN SDK+ ++R++PD RH C K++ LP TS++I FHNE S+LLRTV SVL + Sbjct: 103 KFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKK 162 Query: 172 SPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTRMLGASVATGD 231 SPP L+ EI+LVDD+S+ + VR+LR +REGL+R+R+ GA A Sbjct: 163 SPPHLIKEIILVDDYSNDPEDGA----LLGKIEKVRVLRNDRREGLMRSRVRGADAAQAK 218 Query: 232 VITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWE 291 V+TFLDSHCE N +WL PLL+R+A +R +V P+IDVI+ D+F+Y + D ++G FDW Sbjct: 219 VLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASAD-LKGGFDWN 277 Query: 292 MYYKRIPIPPELQKA---DPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYE 348 + +K + PE +++ +P P ++P++AGGLF +D+ +F ELG YD +++WGGE E Sbjct: 278 LVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLE 337 Query: 349 ISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVP--AGVSLARNLKRVAEVWMDEYAEYIY 406 ISF+VW CGG +E IPCSRVGH++RK PY P +G ARN +R AEVWMDEY + Y Sbjct: 338 ISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYY 397 Query: 407 QRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPP---AAAWGEI 463 P R++ G++ + +LR L+CK FKW++ + YP + P A+G + Sbjct: 398 AAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENV-------YPELRVPDHQDIAFGAL 450 Query: 464 RNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFC 523 + GT C DT + + C G W T + ++ D C Sbjct: 451 QQ-GTN-CLDTLGHFADGVVGVYECHNAGGNQEW------ALTKEKSVKHMD------LC 496 Query: 524 FDAISH--TSPVTLYDCHSMKGNQLW-KYRKDKTLYHPVSGSCMD-CSESDHRIFMNTCN 579 + S + L C Q W + + L H S C+D + + + C Sbjct: 497 LTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCG 556 Query: 580 PSSLTQQWLF 589 P +L+QQW F Sbjct: 557 P-ALSQQWKF 565 >2Z87-A nrPDB Length = 624 Score = 268 bits (685), Expect = 5e-72, Method: Composition-based stats. Identities = 51/244 (20%), Positives = 99/244 (40%), Gaps = 31/244 (12%) Query: 148 SIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVR 207 SI+IP +N + +L + L E+++ DD S +E++++ + ++ +L +++ Sbjct: 95 SIVIPTYNR--AKILAITLACLCNQKTIYDYEVIVADDGS-KENIEEIVREFESLL-NIK 150 Query: 208 ILRTKKR-EGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKT-IVCP- 264 +R K L R LG A + + LD N W+ ++ +A + ++ P Sbjct: 151 YVRQKDYGYQLCAVRNLGLRAAKYNYVAILDCDMAPNPLWVQSYMELLAVDDNVALIGPR 210 Query: 265 -MIDVIDHDDFRYETQ----------------AGDAMRG-AFDWEMYYKRIPIPPELQKA 306 ID H + +Q AG + + DW + + + L Sbjct: 211 KYIDTSKHTYLDFLSQKSLINEIPEIITNNQVAGKVEQNKSVDWRIEHFKNTDNLRL--- 267 Query: 307 DPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCS 366 + PF +GG A +KW + G +D WGGE E ++++ G + + Sbjct: 268 -CNTPFR--FFSGGNVAFAKKWLFRAGWFDEEFTHWGGEDNEFGYRLYREGCYFRSVEGA 324 Query: 367 RVGH 370 H Sbjct: 325 MAYH 328 >1IT0-A nrPDB Length = 436 Score = 66.3 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 22/141 (15%) Query: 455 PPAAAWGEIRNVGTGLCADTKHGAL--GSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIR 512 PP + G+I+ VG+G C D + + G+ ++L C Q +T+T ++R Sbjct: 307 PPPSGGGQIKGVGSGRCLDVPNASTTDGTQVQLYDCHSA-------TNQQWTYTDAGELR 359 Query: 513 PGDPQHTKKFCFDAISHTS--PVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC---- 566 + C DA + V +Y C NQ W+ D ++ SG C+D Sbjct: 360 VYGDK-----CLDAAGTGNGTKVQIYSCWGGD-NQKWRLNSDGSIVGVQSGLCLDAVGGG 413 Query: 567 SESDHRIFMNTCNPSSLTQQW 587 + + I + +C + Q+W Sbjct: 414 TANGTLIQLYSC-SNGSNQRW 433 >3WN1-A nrPDB Length = 438 Score = 64.4 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 24/140 (17%) Query: 458 AAWGEIRNVGTGLCADTKHGA--LGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGD 515 A G +R G+ C D G+ G+ L+L C G W + T GD Sbjct: 1 AGSGALRGAGSNRCLDVLGGSQDDGALLQLYDCW-GGTNQQWTSTDTGRLT-----VYGD 54 Query: 516 PQHTKKFCFDAISH----TSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC----S 567 C D H + V ++ C S NQ W+ D T+ SG C++ + Sbjct: 55 K------CLDVPGHATAPGTRVQIWSC-SGGANQQWRVNSDGTVVGVESGLCLEAAGAGT 107 Query: 568 ESDHRIFMNTCNPSSLTQQW 587 + + + TCN Q+W Sbjct: 108 ANGTAVQLWTCNGGG-NQKW 126 >5MLZ-A nrPDB Length = 374 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 38/213 (17%) Query: 148 SIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVR 207 S+IIP +NE + L + S ++ + L EIV+VDD S + ++ + +P V+ Sbjct: 26 SVIIPTYNEREN--LEELFSRIDNALQGLNYEIVVVDDDSPDRTW-EKAQELSSKYP-VK 81 Query: 208 ILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMI- 266 ++R K +GL + G A+GDV +D+ + +P L++ I + Sbjct: 82 VIRRTKEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPKLIEAIKNGSDIAIGSRYV 141 Query: 267 ---DVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFA 323 V + +R G M G RI +P + D DP G FA Sbjct: 142 KGGKVENWPFYRKLISKGAIMVG---------RIALP---KIRDIKDPV------SGFFA 183 Query: 324 VDRKWFWELGGYDPGLEIWGGEQYEISFKVWMC 356 + ++ G E I FK+ M Sbjct: 184 LRKEVVE------------GVELNPIGFKILME 204 >3A22-A nrPDB Length = 614 Score = 60.2 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 30/144 (20%), Positives = 57/144 (39%), Gaps = 24/144 (16%) Query: 454 EPPAAAWGEIRNVGTGLCADTKHGA--LGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDI 511 P + +G CAD + G+ L C G +W T+T R+++ Sbjct: 482 PLPGTNGALVTGKQSGRCADIYNNTITNGTQAELWDC-NGGPNQSW------TYTSRKEL 534 Query: 512 RPGDPQHTKKFCFDA----ISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMD-- 565 + C DA ++ + V ++DC + + NQ W D T+ + +G C+D Sbjct: 535 VLYGNK-----CLDAYNLGTTNGTKVVIWDC-NGQANQKWNINSDGTITNVNAGLCLDAY 588 Query: 566 --CSESDHRIFMNTCNPSSLTQQW 587 + + + + +C Q+W Sbjct: 589 NAATANGTSLVLWSCGTGD-NQKW 611 >5EKE-A nrPDB Length = 341 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Query: 148 SIIIPFHNE--GWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPS 205 SI+IP +NE L + VL +P ++ EI+ V+D S + LK+ ++ Y + Sbjct: 29 SIVIPMYNEEDNLEHLFARLLEVL--TPLKITYEIICVNDGSKDKTLKQLIDCYQSN-RQ 85 Query: 206 VRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDR 253 ++I+ + G G A G+ + +D+ + + L+D+ Sbjct: 86 IKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDK 133 >6HNQ-B nrPDB Length = 345 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 143 TLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDRE-HLKKPLEDYMA 201 ++ S+I+P N G L RT+ SVLN++ E++++DD S+ ++ Y Sbjct: 18 SMKKVSVIMPTFNNG-EKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETLNVIKKYKG 76 Query: 202 LFPSVRILRTKKREGLIRT-RMLGASVATGDVITFLDSH 239 L VR + KK G R G ++ + + FLDS Sbjct: 77 L---VRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSD 112 >2Z49-A nrPDB Length = 432 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 55/159 (34%), Gaps = 25/159 (15%) Query: 445 DLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFT 504 D FY P +G +RN + LC D + + + C N Q F Sbjct: 140 DDQYFYVRSRGPELFYGRLRNEKSDLCLDVEGSDGKGNVLMYSC-------EDNLDQWFR 192 Query: 505 FTWREDIRPGDPQHTKKFCFDA-ISHTS-PVTLYDCHSMKGNQLWKYRKDK-------TL 555 + +I C D S S V +Y C ++ +Q+W R + + Sbjct: 193 YYENGEI----VNAKSGMCLDVEGSDGSGNVGIYRCDDLR-DQMWS-RPNAYCNGDYCSF 246 Query: 556 YHPVSGSCMDCS--ESDHRIFMNTCNPS-SLTQQWLFEH 591 + S C+D S + + C+ +W+F+ Sbjct: 247 LNKESNKCLDVSGDQGTGDVGTWQCDGLPDQRFKWVFDD 285 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 44/140 (31%), Gaps = 22/140 (15%) Query: 458 AAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQ 517 GE+R+ + C D + C G + + T R + R Sbjct: 8 LDIGELRSFKSKQCVDIVGNQGSGNIATYDCD---GLSDQQIIICGDGTIRNEARNYCFT 64 Query: 518 HTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLY-------------HPVSGSCM 564 + +S SP TLY + +Q W+ + KT + SG C+ Sbjct: 65 PDGSGNANVMS--SPCTLY--PEIPSSQRWRQGRRKTFTDNGGIEQVATEIINLASGKCL 120 Query: 565 D--CSESDHRIFMNTCNPSS 582 D S+ I + C Sbjct: 121 DIEGSDGTGDIGVYDCQNLD 140 >1RZO-B nrPDB Length = 262 Score = 48.6 bits (114), Expect = 8e-06, Method: Composition-based stats. Identities = 29/128 (22%), Positives = 51/128 (39%), Gaps = 13/128 (10%) Query: 468 TGLCADTKHG--ALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFD 525 GLC D G+P++L C + WN Q++T IR K Sbjct: 17 NGLCVDVTGEEFFDGNPIQLWPC---KSNTDWN--QLWTLRKDSTIRSN----GKCLTIS 67 Query: 526 AISHTSPVTLYDCHSMK-GNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNT-CNPSSL 583 S V +Y+C + G W+ ++T+ +P SG + + + + N ++ Sbjct: 68 KSSPRQQVVIYNCSTATVGATRWQIWDNRTIINPRSGLVLAATSGNSGTKLTVQTNIYAV 127 Query: 584 TQQWLFEH 591 +Q WL + Sbjct: 128 SQGWLPTN 135 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 44/124 (35%), Gaps = 17/124 (13%) Query: 469 GLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAIS 528 G+C A + LE C + E W IR PQ + C + Sbjct: 149 GMCL----QANSGKVWLEDCTSEKAEQQW------ALYADGSIR---PQQNRDNCLTTDA 195 Query: 529 --HTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNP--SSLT 584 + V + C Q W ++ D T+ + +G +D SD + +P +L Sbjct: 196 NIKGTVVKILSCGPASSGQRWMFKNDGTILNLYNGLVLDVRRSDPSLKQIIVHPFHGNLN 255 Query: 585 QQWL 588 Q WL Sbjct: 256 QIWL 259 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 522 FCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGS--CMDCSESDHR--IFMNT 577 C +++ V L DC S K Q W D ++ P C+ + + + + Sbjct: 150 MCLQ--ANSGKVWLEDCTSEKAEQQWALYADGSIR-PQQNRDNCLTTDANIKGTVVKILS 206 Query: 578 CNPSSLTQQWLFEHTNSTVLEKFN 601 C P+S Q+W+F++ + T+L +N Sbjct: 207 CGPASSGQRWMFKN-DGTILNLYN 229 >3RTJ-B nrPDB Length = 262 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 42/124 (33%), Gaps = 17/124 (13%) Query: 469 GLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAIS 528 GLC A + +E C + E W IR PQ + C + S Sbjct: 149 GLCL----QANSGQVWIEDCSSEKAEQQW------ALYADGSIR---PQQNRDNCLTSDS 195 Query: 529 --HTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNPS--SLT 584 + V + C Q W ++ D T+ + SG +D SD + P Sbjct: 196 NIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPN 255 Query: 585 QQWL 588 Q WL Sbjct: 256 QIWL 259 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 56/142 (39%), Gaps = 18/142 (12%) Query: 461 GEIRNVGTGLCADTKHGALGSPLRLEGCVRG--RGEAAWNNMQVFTFTWREDIRPGDPQH 518 G I N + L G G+ L ++ + +G NN Q F T Sbjct: 96 GTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQPFVTT---------IVG 146 Query: 519 TKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGS--CM--DCSESDHRIF 574 C +++ V + DC S K Q W D ++ P C+ D + + + Sbjct: 147 LYGLCLQ--ANSGQVWIEDCSSEKAEQQWALYADGSIR-PQQNRDNCLTSDSNIRETVVK 203 Query: 575 MNTCNPSSLTQQWLFEHTNSTV 596 + +C P+S Q+W+F++ + + Sbjct: 204 ILSCGPASSGQRWMFKNDGTIL 225 >2Q3N-B nrPDB Length = 267 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 48/132 (36%), Gaps = 17/132 (12%) Query: 469 GLCADTKHGA--LGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDA 526 GLC D A G+P+ L C + Q++T + IR +K C Sbjct: 23 GLCVDVSDNAYNNGNPIILWKC-----KDQLEVNQLWTLKSDKTIR------SKGKCLTT 71 Query: 527 I--SHTSPVTLYDCHS-MKGNQLWKYRKDKTLYHPVSGSCMDC-SESDHRIFMNTCNPSS 582 + + V +YDC S + W + T+ +P SG + S S N Sbjct: 72 YGYAPGNYVMIYDCSSAVAEATYWDIWDNGTIINPKSGLVLSAESSSMGGTLTVQKNDYR 131 Query: 583 LTQQWLFEHTNS 594 + Q W + S Sbjct: 132 MRQGWRTGNDTS 143 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 37/109 (33%), Gaps = 10/109 (9%) Query: 488 CVRGRGEAAW-------NNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHS 540 C+ G + W Q + IRP + C + + + + C + Sbjct: 156 CMEAHGNSMWLDVCDITKEEQQWAVYPDGSIRPVQNTNNCLTC-EEHKQGATIVMMGCSN 214 Query: 541 MKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNP--SSLTQQW 587 +Q W ++ D T+Y+ MD SD + P + Q W Sbjct: 215 AWASQRWVFKSDGTIYNLYDDMVMDVKSSDPSLKQIILWPYTGNANQMW 263 >5TZ8-A nrPDB Length = 572 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Query: 148 SIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFP-SV 206 S+I+P +N + ++S+ + P+ E+V+VDD S + L+ +E Y V Sbjct: 4 SVIVPTYN-SEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQ-IVEKYRNKLNLKV 61 Query: 207 RILRTKKREGLIRTRMLGASVATGDVITFLDSH 239 L T G + R + A G+ + F+DS Sbjct: 62 SQLETNS-GGPGKPRNVALKQAEGEFVLFVDSD 93 >3CAH-A nrPDB Length = 258 Score = 41.7 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 59/171 (34%), Gaps = 63/171 (36%) Query: 469 GLCADTKHG--ALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDA 526 GLC D ++G G+PL+L C R Q +TF + IR C A Sbjct: 12 GLCVDVRNGYDTDGTPLQLWPCGTQR-------NQRWTFDSDDTIRSMGK------CMTA 58 Query: 527 --ISHTSPVTLYDCHSMKGN-QLWKYRKDKTLYHPVSGS--------------------- 562 +++ S + +++C + N W+ D ++ +P SG Sbjct: 59 NGLNNGSNIVIFNCSTAAENAIKWEVPIDGSIINPSSGLVMTAPRAASRTILLLEDNIYA 118 Query: 563 ------------------------CMDCSESDHRIFMNTCNPSSLTQQWLF 589 C+ + ++ ++M C +SL QQW Sbjct: 119 ASQGWTVTNNVKPIVASIVGYKEMCLQSNGENNGVWMEDCEATSLQQQWAL 169 Score = 35.1 bits (79), Expect = 0.084, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 37/103 (35%), Gaps = 4/103 (3%) Query: 497 WNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLY 556 + Q +T T K+ C + + V + DC + Q W D+T+ Sbjct: 117 YAASQGWTVTNNVKPIVASIVGYKEMCLQSNGENNGVWMEDCEATSLQQQWALYGDRTIR 176 Query: 557 -HPVSGSCMDCS--ESDHRIFMNTCNPSSLTQQWLFEHTNSTV 596 + G C+ + S I + C +Q+W F + V Sbjct: 177 VNSTRGLCVTTNGYNSKDLIIILKCQGLP-SQRWFFNSDGAIV 218 >5Y97-C nrPDB Length = 264 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 32/188 (17%), Positives = 56/188 (29%), Gaps = 50/188 (26%) Query: 449 FYPPVEPPAAAW-----GEIRNVGTGLCADTKHGALGSPLRLEGCVRG-----------R 492 YP + W G +R++G C T + G+ + + C + Sbjct: 35 LYPCGQQVNQKWTFHSDGTVRSLG--KCLATNNSKFGNLVVIYDCSKLAAEDISWDVSVG 92 Query: 493 GEAAWNNMQVFTFTWREDIRP--------------------------GDPQHTKKFCFDA 526 G N + T + R G C +A Sbjct: 93 GTIMNPNYEDLALTSNKATRSTNLTMEVNTYSASQGWRVGNYVQPIIGSIVGLDDMCLEA 152 Query: 527 ISHTSPVTLYDCHSMKGNQLWKYRKDKTLY-HPVSGSCMDCSESDHR----IFMNTCNPS 581 + + L +C + Q W D T+ C+ S S + I + C+ S Sbjct: 153 TDGNTNMWLEECVPNQREQSWALYSDGTIRVDDNRELCVTASSSTYDNWKVITILNCDGS 212 Query: 582 SLTQQWLF 589 + Q+W+F Sbjct: 213 N-NQRWVF 219 >3L7K-A nrPDB Length = 729 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 18/121 (14%), Positives = 46/121 (38%), Gaps = 10/121 (8%) Query: 148 SIIIPFHNEGWSSLLRTVHSVLN--RSPPELVAEIVLVDDFSDREHLKKPLEDYMALFP- 204 +II+ ++N + L + +++V+D S + KK +++ + + Sbjct: 5 TIIVTYYNAE-----EYITGCLESIKQQRTQDFNLIIVNDGSTDQS-KKLMDEAIKDYDK 58 Query: 205 SVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCP 264 ++R + + G R + FLD+ E + L++ ++ P Sbjct: 59 NIRFIDLDENSGHAHARNIALEEVETPYFMFLDADDELASYAITFYLEKFNNTDG-LIAP 117 Query: 265 M 265 + Sbjct: 118 I 118 >1HWM-B nrPDB Length = 266 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 37/147 (25%), Positives = 52/147 (35%), Gaps = 15/147 (10%) Query: 461 GEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHT- 519 G I N +GL GA + L LE + W T D++P Sbjct: 96 GSIINPSSGLVMTAPSGASRTTLLLENNIHA-ASQGW--------TVSNDVQPIATLIVG 146 Query: 520 -KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVS-GSCMDCSE--SDHRIFM 575 + C A + V + DC Q W D+T+ S G C+ + S I + Sbjct: 147 YNEMCLQANGENNNVWMEDCDVTSVQQQWALFDDRTIRVNNSRGLCVTSNGYVSKDLIVI 206 Query: 576 NTCNPSSLTQQWLFEHTNSTVLEKFNR 602 C + TQ+W F S V K R Sbjct: 207 RKCQGLA-TQRWFFNSDGSVVNLKSTR 232 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 58/171 (33%), Gaps = 63/171 (36%) Query: 469 GLCADTKHG--ALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDA 526 GLC D ++G G+P++L C R Q +TF + IR C A Sbjct: 20 GLCVDVRNGYDTDGTPIQLWPCGTQR-------NQQWTFYNDKTIRSMGK------CMTA 66 Query: 527 --ISHTSPVTLYDCHSMKGN-QLWKYRKDKTLYHPVSGS--------------------- 562 ++ S + + DC + + W+ D ++ +P SG Sbjct: 67 NGLNSGSYIMITDCSTAAEDATKWEVLIDGSIINPSSGLVMTAPSGASRTTLLLENNIHA 126 Query: 563 ------------------------CMDCSESDHRIFMNTCNPSSLTQQWLF 589 C+ + ++ ++M C+ +S+ QQW Sbjct: 127 ASQGWTVSNDVQPIATLIVGYNEMCLQANGENNNVWMEDCDVTSVQQQWAL 177 >1ABR-B nrPDB Length = 267 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 36/112 (32%), Gaps = 14/112 (12%) Query: 488 CVRGRGEAAW-------NNMQVFTFTWREDIRPGDPQHTKKFCFDAISH--TSPVTLYDC 538 C++ +G W Q + IR C + H S + L C Sbjct: 156 CMQAQGSNVWMADCDSNKKEQQWALYTDGSIR---SVQNTNNCLTSKDHKQGSTILLMGC 212 Query: 539 HSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNP--SSLTQQWL 588 + +Q W ++ D ++Y MD SD + P Q WL Sbjct: 213 SNGWASQRWVFKNDGSIYSLYDDMVMDVKGSDPSLKQIILWPYTGKPNQIWL 264 Score = 37.0 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 26/169 (15%), Positives = 46/169 (27%), Gaps = 59/169 (34%) Query: 469 GLCADT--KHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDA 526 G+C D G+ + + C + Q++T + IR C Sbjct: 23 GMCVDVYDNGYHNGNRIIMWKC-----KDRLEENQLWTLKSDKTIRSNGK------CLTT 71 Query: 527 I--SHTSPVTLYDCHS-MKGNQLWKYRKDKTLYHPVSGSCMDCSESDHR----------- 572 + S V +YDC S + W+ + T+ +P S + S Sbjct: 72 YGYAPGSYVMIYDCTSAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGTLTVQTNEYL 131 Query: 573 --------------------------------IFMNTCNPSSLTQQWLF 589 ++M C+ + QQW Sbjct: 132 MRQGWRTGNNTSPFVTSISGYSDLCMQAQGSNVWMADCDSNKKEQQWAL 180 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 461 GEIRNVG-TGLCADTKHGALGSPLRLEGCVRGRGEAAW 497 G IR+V T C +K GS + L GC G W Sbjct: 184 GSIRSVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRW 221 >2MLL-B nrPDB Length = 255 Score = 36.7 bits (83), Expect = 0.029, Method: Composition-based stats. Identities = 31/184 (16%), Positives = 61/184 (33%), Gaps = 48/184 (26%) Query: 456 PAAAW-----GEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGE----AAWNN------- 499 P W G IR+ G+ C T G + + C GE W N Sbjct: 42 PNQLWTIKRDGTIRSNGS--CLTTYGYTAGVYVMIFDCATAVGEATVWQIWGNGTIINPR 99 Query: 500 -----------------MQVFTFTWREDIRPGDPQHTKK--------FCFDAISHTSPVT 534 +Q +T + G+ ++ C ++ VT Sbjct: 100 SNLVLAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPREVTIYGFNDLCMESG--GGSVT 157 Query: 535 LYDCHSMKGNQLWKYRKDKTLY-HPVSGSCMDCS-ESDHRIFMNTCNPSSLTQQWLFEHT 592 + C S K ++ W D ++ C+ +S + + +C+ ++ Q+W+F + Sbjct: 158 VETCSSGKADK-WALYGDGSIRPEQNQAQCLTSGGDSVAGVNIVSCSGAASGQRWVFTNE 216 Query: 593 NSTV 596 + + Sbjct: 217 GAIL 220 >4ZFY-B nrPDB Length = 261 Score = 36.3 bits (82), Expect = 0.040, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 9/81 (11%) Query: 522 FCFDA----ISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHR--IFM 575 C D + S V LY C + NQ W + D T+ G C+ S + + Sbjct: 19 LCVDVYGALTADGSRVILYPCGQ-QQNQQWTFYPDNTIRSL--GKCLATSALSSGSNVVI 75 Query: 576 NTCNPSSLTQQWLFEHTNSTV 596 C+ W+ + + + Sbjct: 76 TNCDYLRYDDGWMVSSSGTMM 96 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 30/73 (41%), Gaps = 4/73 (5%) Query: 520 KKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLY-HPVSGSCMDCSESDHR--IFMN 576 + C +A + + V L C K Q W D T+ + C+ S I + Sbjct: 145 RHMCLEATDNDTNVWLESCVKNKTKQYWALYSDDTIRVNNNRNLCVSSSTDSSSKLIVIR 204 Query: 577 TCNPSSLTQQWLF 589 C+ S + Q+W+F Sbjct: 205 RCDGS-INQRWVF 216 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 44/126 (34%), Gaps = 14/126 (11%) Query: 469 GLCADTKHGAL--GSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDA 526 GLC D GS + L C + + Q +TF IR K A Sbjct: 18 GLCVDVYGALTADGSRVILYPCGQQQ-------NQQWTFYPDNTIR----SLGKCLATSA 66 Query: 527 ISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMN-TCNPSSLTQ 585 +S S V + +C ++ + W T+ + S + + + R + N + Q Sbjct: 67 LSSGSNVVITNCDYLRYDDGWMVSSSGTMMNKSSHLVLTANAATSRTNLTGENNVFAAKQ 126 Query: 586 QWLFEH 591 W + Sbjct: 127 AWRIGN 132 >4P02-A nrPDB Length = 803 Score = 35.5 bits (80), Expect = 0.062, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 38/103 (36%), Gaps = 11/103 (10%) Query: 142 ETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA 201 E LP I++P +NE L T+ + N P + +VL DD + P + Sbjct: 138 EELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQ 197 Query: 202 LFPSVRILRTKKREGLIR-------TRMLGASVATGDVITFLD 237 R ++ + L R TR G++ L+ Sbjct: 198 KAQE----RRRELQQLCRELGVVYSTRERNEHAKAGNMSAALE 236 >1GGP-B nrPDB Length = 254 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Query: 519 TKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLY-HPVSGSCMDCSESDH--RIFM 575 + + C A + + + + +C + K Q W DK++ S +C+ + I + Sbjct: 138 SAQLCMQAGNGPANLWMSECRAGKAEQQWALLTDKSIRSETNSDNCLTSAADAGPKTILL 197 Query: 576 NTCNPSSLTQQWLFEHTNSTV 596 C+ + +Q+W+F+ S + Sbjct: 198 ALCSGPA-SQRWVFDDDGSIL 217 >3D7W-B nrPDB Length = 265 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 31/185 (16%), Positives = 57/185 (30%), Gaps = 48/185 (25%) Query: 456 PAAAW-----GEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGE----AAWNN------- 499 P W G IR+ G+ C T G + + C E W N Sbjct: 46 PNQLWTIKKDGTIRSNGS--CLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINPR 103 Query: 500 -----------------MQVFTFTWREDIRPGDPQHTKK--------FCFDAISHTSPVT 534 +Q +T + G+ ++ C + S V Sbjct: 104 SNLVLAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPRETTIYGFRDLCME--SAGGSVY 161 Query: 535 LYDCHSMKGNQLWKYRKDKTLY-HPVSGSCMD--CSESDHRIFMNTCNPSSLTQQWLFEH 591 + C + + NQ W D ++ + C+ I + +C+ S Q+W+F + Sbjct: 162 VETCTAGQENQRWALYGDGSIRPKQLQSQCLTNGRDSISTVINIVSCSAGSSGQRWVFTN 221 Query: 592 TNSTV 596 + + Sbjct: 222 EGAIL 226 >2VLC-A nrPDB Length = 570 Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 39/110 (35%), Gaps = 9/110 (8%) Query: 488 CVRGRGEAAW-------NNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHS 540 C++ G+A W Q + IRP + D S S + + C Sbjct: 458 CMQANGDAMWVVECESSKAEQKWALYPDGSIRPHQDRDRCLTSTDNHSQGSIIIISSCSP 517 Query: 541 MKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNPS--SLTQQWL 588 Q W + D T+ + +G MD SD + P+ Q+WL Sbjct: 518 GSEGQRWVFMNDGTILNLKNGLVMDVKGSDPSLHQIIIWPATGKPNQKWL 567 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 58/176 (32%), Gaps = 44/176 (25%) Query: 461 GEIRNVGTGLCADTKHGALGSPLRLEGCVR-----------GRGE----------AAWNN 499 G IR+ G C T + G + + C G +A + Sbjct: 362 GTIRSNG--KCLTTNGYSAGDYVMIYDCRTPVTAASIWQFWANGTIINPQSALVLSAESG 419 Query: 500 MQVFTFTWREDI---RPG------------DPQHTKKFCFDAISHTSPVTLYDCHSMKGN 544 T T + DI R G C A V +C S K Sbjct: 420 NPRTTLTVQADIYASRQGWLAGNNTEPFVTSIVGFNDLCMQANGDAMWVV--ECESSKAE 477 Query: 545 QLWKYRKDKTLY-HPVSGSCMDCSESDHR---IFMNTCNPSSLTQQWLFEHTNSTV 596 Q W D ++ H C+ +++ + I +++C+P S Q+W+F + + + Sbjct: 478 QKWALYPDGSIRPHQDRDRCLTSTDNHSQGSIIIISSCSPGSEGQRWVFMNDGTIL 533 >2FTC-A nrPDB Length = 189 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 7/67 (10%) Query: 383 GVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKI 442 G + A + ++W DE Y PE + +LR LN K K I Sbjct: 52 GAAFAGGTSLIQKIWDDEIVADFYVAVPEI-------MPELNRLRKKLNKKYPKLSRNSI 104 Query: 443 AWDLPKF 449 D+PK Sbjct: 105 GRDIPKM 111 >1YF8-B nrPDB Length = 255 Score = 33.2 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 32/181 (17%), Positives = 53/181 (29%), Gaps = 42/181 (23%) Query: 456 PAAAW-----GEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGE----AAWNNMQVFTFT 506 P W G IR+ G+ C T G + + C E W N + Sbjct: 42 PNQLWTIKRDGTIRSNGS--CLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINPR 99 Query: 507 WREDIRPGDPQHTKKFCFD-----------AISHTSP--VTLYD----CHSMKG------ 543 + A + T+P VT+Y C G Sbjct: 100 SNLALAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPREVTIYGFNDLCMESNGGSVWVE 159 Query: 544 ------NQLWKYRKDKTLY-HPVSGSCMDCS-ESDHRIFMNTCNPSSLTQQWLFEHTNST 595 N W D ++ C+ +S I + +C+ S Q+W+F + + Sbjct: 160 TCVSQQNDRWALYGDGSIRPEQNQDQCLTSGRDSVAGINIVSCSGGSSGQRWVFTNEGAI 219 Query: 596 V 596 + Sbjct: 220 L 220 >4V8M-AF nrPDB Length = 144 Score = 32.4 bits (72), Expect = 0.52, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 5/79 (6%) Query: 162 LRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTR 221 L V L+R L VL DD D E+ K L +A ++ ++ +RE L + Sbjct: 50 LSEVTRALDRRTAHL---CVLADDCEDEEY--KKLVTALAKQNNIDLVSMDEREKLAQWA 104 Query: 222 MLGASVATGDVITFLDSHC 240 L A G V L C Sbjct: 105 GLTRMAADGSVRKTLKCSC 123 >4DND-A nrPDB Length = 130 Score = 31.6 bits (70), Expect = 0.97, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 43/118 (36%), Gaps = 12/118 (10%) Query: 318 AGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFK--VWMCGGRMEDIPCSRVGHIYRKY 375 +G + +F + DP + G Q ++ ++ + + VG R+ Sbjct: 9 SGVDLGTENLYFQSMSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQ-ESAAVG---REE 64 Query: 376 VPYKVPAGVSLARNLKRVAEVWMDEYAEYI--YQRRPEYRHLSAGDVAVQKKLRSSLN 431 + + + RN R E +++ E I + P L AGD+ +K + Sbjct: 65 LDWT----TNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMR 118 >5Z70-A nrPDB Length = 605 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 28/87 (32%), Gaps = 13/87 (14%) Query: 255 ARNRKTIVCPMIDVIDHDDFRYETQ-----------AGDAMRGAFD-WEMYYKRIPIPPE 302 A + P D D ++ + G R ++ + K P+ Sbjct: 287 APDLTRATTPPGDSSDWALWQNLAKKSHVFGKPEKFCGQPSRSMWESATLTCKPSPLTER 346 Query: 303 LQKADPSDPFESPVMAGGLFAV-DRKW 328 L+ +DP+ + GG+ D W Sbjct: 347 LKDLSINDPYSGKTVTGGIITFTDSNW 373 >3NBC-A nrPDB Length = 148 Score = 30.1 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 14/113 (12%), Positives = 33/113 (29%), Gaps = 15/113 (13%) Query: 491 GRGEAAWNNMQV--------FTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMK 542 G G W +Q+ + +R D +PV++ + Sbjct: 43 GYGNQQWTLVQLPHTTIYTMQAVNPQSYVRVRDDNLVDGAALVGSQQPTPVSIESAGNSG 102 Query: 543 GNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNST 595 ++ + + + + I + + +S Q W FE ++ Sbjct: 103 QFRI-------KIPNLGLALTLPSDANSTPIVLGEVDETSTNQLWAFESVSAV 148 >1XX5-A nrPDB Length = 221 Score = 29.0 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 13/30 (43%), Gaps = 2/30 (6%) Query: 384 VSLARNLKRVAEVWMDEYAEYIY--QRRPE 411 S AR + +W DEY ++Y P Sbjct: 80 SSNARTWTEIIHLWHDEYKNFVYGVGANPP 109 >2WAU-A nrPDB Length = 302 Score = 29.0 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 29/178 (16%), Positives = 58/178 (32%), Gaps = 24/178 (13%) Query: 383 GVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAV--QKKL---RSSLNCKSFKW 437 G + +N KR + W D +I++ + G+++ +K L + + +W Sbjct: 122 GDGVGQNEKR--KKWWDMNKYHIWESMLSGYKHAYGNISENDRKMLDIPNNDDEHQFLRW 179 Query: 438 FMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAW 497 F K E+ C K + + C A Sbjct: 180 FQEWTENFCTKR-----------NELYENMVTACNSAKCNTSNGSVDKKEC-----TEAC 223 Query: 498 NNMQVFTFTWREDIRPGDPQHTKKFCFDAISHT-SPVTLYDCHSMKGNQLWKYRKDKT 554 N F +++ + + Q+ + SP D + + + L +Y KD+T Sbjct: 224 KNYSNFILIKKKEYQSLNSQYDMNYKETKAEKKESPEYFKDKCNGECSCLSEYFKDET 281 >4D8J-B nrPDB Length = 150 Score = 29.0 bits (63), Expect = 7.2, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Query: 194 KPLEDYMALFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANV--NWLPPLL 251 + LE+ + + + L K REG + TR + AS A V L E + W+ + Sbjct: 4 QQLENLESGW-KWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHM 62 Query: 252 DRIARNR 258 + NR Sbjct: 63 NPELVNR 69 >2DM9-A nrPDB Length = 198 Score = 28.6 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 6/71 (8%) Query: 164 TVHSVLNRSPPELVAEIVLVDDF--SDREHLKKPLEDYMALFPSVRILRTKKREGLIRTR 221 + SVL L E + D++ S + LK+ +++ VR++ +K GLI +R Sbjct: 82 IISSVLEEVKRRL--ETMSEDEYFESVKALLKEAIKELNEK--KVRVMSNEKTLGLIASR 137 Query: 222 MLGASVATGDV 232 + GDV Sbjct: 138 IEEIKSELGDV 148 >2HK2-A nrPDB Length = 331 Score = 28.6 bits (62), Expect = 8.3, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 8/96 (8%) Query: 338 GLEIW-GGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPA--GVSLARNLKRVA 394 G W G E S+ V + ED + + + KVP+ G+SL RN R Sbjct: 153 GFAEWEKGYSDETSYAVPLESNHFED-DLAMIFVVI-NQHSKKVPSRYGMSLTRNTSRFY 210 Query: 395 EVWMDEYAEYIYQRRPEYRHLSA---GDVAVQKKLR 427 + W+D E + + + + G+V + LR Sbjct: 211 QYWLDHIDEDLAEAKAAIQDKDFKRLGEVIEENGLR 246 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.127 0.359 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,261,598 Number of Sequences: 36641 Number of extensions: 1012298 Number of successful extensions: 2521 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 2375 Number of HSP's gapped (non-prelim): 90 length of query: 603 length of database: 10,336,785 effective HSP length: 103 effective length of query: 500 effective length of database: 6,562,762 effective search space: 3281381000 effective search space used: 3281381000 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.6 bits)